Miracle-dz/UniFAR-FTUs huggingface dataset:
Gliomatose Cerebral: Caso Clínico e Revisão da Literatura

We report a case of gliomatosis cerebri that after two episodes of severe intracranial hypertension, started palliative chemotherapy and progressed satisfactory clinically and imagiologically. A 33-year-old male patient, previously autonomous (Karnofsky Performance Status Scale of 100 points) and with no relevant personal/familiar history, is investigated with brain computed tomography and magnetic resonance imaging after an inaugural seizure. A right fronto-parietal infiltrative lesion with contralateral extension through the splenium of the corpus callosum was detected. A neuronavigation lesion biopsy was performed and the histological diagnosis revealed an astrocytoma grade II (WHO), defining a gliomatosis cerebri. After hospital discharge, he returns two times to the emergency department with severe intracranial hypertension. After hospitalization and intravenous corticosteroid therapy, he recovers neurologically to his basal state. Twenty-seven months after the diagnosis, the patient is asymptomatic, with no focal neurological deficits and with imaging stability of the lesion. Gliomatosis cerebri is a rare neoplasm, with a variable clinical presentation and a diagnosis based on imaging and histological characteristics. After the start of the complementary treatments, such as chemotherapy, it is possible to get a long term clinical and imaging stabilization. Received: 10/10/2016 - Accepted: 05/09/2017
Efﬁcient Probabilistic Supergraph Search over Uncertain Graphs

Given a query graph q , retrieving the data graphs g from a set D of data graphs such that q contains g , namely supergraph containment search, is fundamental in graph data analysis with a wide range of real applications. It is very challenging due to the NP-Completeness of subgraph isomorphism testing. Consider that in many applications, graph data are often uncertain due to various reasons. In this paper, we study the problem of probabilistic supergraph search; that is, given a set D of uncertain data graphs, a certain query graph q and a probability threshold θ , we retrieve the data graphs g u from D such that the probability of q containing g u is not smaller than θ . We show that besides the NP-Completeness of subgraph isomorphism testing, the problem of calculating probabilities is #P-Complete; thus it is even more challenging than the supergraph containment search. To tackle the computational hardness, we ﬁrst propose two novel and effective pruning rules to efﬁciently prune non-promising data graphs. Then, efﬁcient veriﬁ-cation algorithms are developed with the aim of sharing computation and terminating non-promising computation as early as possible. Extensive performance studies on both real and synthetic data demonstrate the efﬁciency and effectiveness of our techniques in practice.
Selecting Appropriate Metrics for Evaluation of Recommender Systems

The abundance of information on the web makes it difficult for users to find items that meet their information need effectively. To deal with this issue, a large number of recommender systems based on different recommender approaches were developed which have been used successfully in a wide variety of domains such as e-commerce, e-learning, e-resources, and egovernment among others. Moreover, in order for a recommender system to generate good quality of recommendations, it is essential for a researcher to find the most suitable evaluation metric which best matches a given recommender algorithm and a recommender's task. However, with the availability of several recommender tasks, recommender algorithms, and evaluation metrics, it is often difficult for a researcher to find their best combination. This paper aims to discuss various evaluation metrics in order to help researchers to select the most appropriate metric which matches a given task and an algorithm so as to provide good quality of recommendations.
Design & Analysis of MIMO Microstrip Antenna with Improved Mutual Coupling

2Principal, AISSMS COE, Maharashtra, India 3HOD Dept. of E&TC Engineering, AISSMS COE, Maharashtra, India ------------------------------------------------------------------------***------------------------------------------------------------------------Abstract—: This work presents a defected ground structure (DGS) for a dual component multiple input multiple output (MIMO) antenna with improved mutual coupling. Defected ground structure is accepted as an arising approach for enhancing the different parameters of microwave circuits, which are narrow bandwidth, low gain and isolation. The two-element MIMO antenna operates at 3.3 GHz. The designed mimo antenna has a compress size of 26 mm × 40 mm suitable for practical design of an antenna. The antenna can be applicable for WLAN, Wi-Max, Wi-Fi which covers a patch operating at a frequency range 2.7 GHz to 5.1GHz. The antenna attains peak gain of 1.17 dB. Efficiency of the antenna is 94%.
The Effect of Toulene on the Microbial Community of a River in Northeastern Ohio, USA

ABSTRACT The effect of toluene on microbial communities from two sites a reference site with minimal anthropogenic disturbance and a polluted site with high levels of xenobiotic compounds along the Mahoning River (Ohio, USA) was examined in flask and microcosm experiments. Total numbers of bacteria and protozoa were determined using fluorescent stains, and bacteria of three species (Burkholderia cepacia, Pseudomonas putida and Acinetobacter calcoaceticus) were enumerated using fluorescent in situ hybridization. In water, total bacterial numbers were not adversely affected by toluene. In sediments, the number of bacteria in the toluene-treated microcosms was lower than controls, particularly in samples from the polluted site. In general, P. putida and A. calcoaceticus population sizes were lower in toluene-treated microcosms than in controls, while B. cepacia numbers were enhanced by the presence of toluene, especially in the polluted site microcosms. Treatment with toluene had a negative effect on protozoa in polluted site microcosms compared to those in reference site microcosms.
Patterns of Tree Species Usage by Long-Horned Beetles (Coleoptera: Cerambycidae) in Fiji1

Abstract: This study investigated cerambycid long-horned beetles in a lowland tropical forest in Fiji and produced 18 new records of beetle-tree associations along with data on beetle phenology and development times. Beetles were reared from timber baits exposed for 1 month to ovipositing females in the Savura Forest Park, Viti Levu. Twelve native, locally common tree species representing 10 families were examined. For each tree, two baits consisting of 16 kg of freshly cut branches were exposed in each of four time periods between June 2008 and May 2009. Eighteen cerambycid species and 557 individual beetles were reared from the 96 baits, with three of the beetle species probably being undescribed. Ceresium was the most abundant genus, representing almost 90% of all individuals reared, with most adults emerging between 4 and 6 months after the timber baits were exposed. Seventeen of the 18 beetle species each emerged from timber belonging to a single tree species, although more rearing records are required to support the high level of host-plant specificity reported here.
Effect of Geographical Location, Year, and Cultivar on Survival of Malus sp. Dormant Buds Stored in Vapors of Liquid Nitrogen

Clonal woody crop germplasm collections often originate and are grown in distinct geographical locations. Because the degree of cold-hardiness is known to be a factor in the successful use of dormant bud cryopreservation for Malus, it was suggested that material from relatively warmer climates would not respond to cryopreservation as well as material from colder environments. To test this hypothesis, the effect of growing provenance on cryosurvival of dormant buds from three Malus (apple) cultivars grown in three locations (Geneva, NY; Davis, CA; and Corvallis, OR) was tested in 3 consecutive years. Dormant winter buds were harvested at the three locations, cryopreserved, and bud viability was tested by grafting. The collective 3-year mean viability for cryopreserved dormantapple buds for the three locations ranged from 63% to 81% of the buds surviving with the highest survival from the Corvallis site; however, the Geneva twigs were exposed to the lowest preharvest temperature. These results suggest that the temperature at the growinglocation may not hinder application of the dormant bud cryopreservationmethod with Malus to the extent previously speculated.
The Benefit of Power Posing Before a High-Stakes Social Evaluation

The current experiment tested whether changing one‘s nonverbal behavior prior to a high-stakes social evaluation could improve performance in the evaluated task. Participants adopted expansive, open (high-power) poses, or contractive, closed (low-power) poses, and then prepared and delivered a speech to two evaluators as part of a mock job interview, a prototypical social evaluation. All speeches were videotaped and coded for overall performance and hireability, and the potential mediators of speech quality (e.g., content, structure) and presentation quality (e.g., captivating, confident). As predicted, high power posers performed better and were more likely to be chosen for hire, and this relationship was mediated only by presentation quality, not speech quality. Power pose condition had no effect on body posture during the social evaluation, thus highlighting the relationship between preparatory nonverbal behavior and subsequent performance.
Complex regulation of gene expression, photosynthesis and sugar levels by pathogen infection in tomato

The infection of plants with pathogens results in the induction of defence reactions as well as changes in carbohydrate metabolism. On the one hand, the pathogen attempts to manipulate the carbohydrate metabolism of the plant for its own advantage. On the other, the plant has to reorganize carbon fluxes to ensure fight against the pathogen. In order to further investigate the connection between pathogen infection and carbohydrate metabolism, the effects of two types of pathogen, biotrophic and necrotrophic, on gene expression, endogenous sugar levels and photosynthesis of tomato plants were analysed. Photosynthetic gene expression was downregulated on infection with Pseudomonas syringae and Botrytis cinerea. In contrast, expression of a sink-specific gene encoding a cell wall invertase and of defence genes was induced by both pathogens. These results provide evidence for a co-regulation of defence, sink and photosynthetic gene expression in planta in response to both types of pathogen. The brassinosteroid-containing plant restorative ComCat enhanced resistance against B. cinerea and counter-regulated the repression of photosynthetic gene expression. Endogenous sugar levels decreased and the hexose to sucrose ratio increased on treatment with B. cinerea. The application of chlorophyll fluorescence imaging revealed the spatio-temporal heterogeneity of the pathogen response. At 24 h after infection, inhibition of photosynthetic electron transport was restricted to the direct vicinity of the infection site, which was surrounded by a circle of increased photosynthetic activity. The photosynthesis of the remaining leaf was not affected at this stage. These results show the usefulness of chlorophyll fluorescence imaging for the assessment of the complex spatio-temporal changes and for the definition of the areas relevant for other types of determination, e.g. gene expression.
Plant response to destruxins visualized by imaging of chlorophyll fluorescence

Kinetic fluorescence imaging was used to set a new detection limit for plant exposure to low levels of destruxins - phytotoxins of Alternaria brassicae. A general experimental algorithm is presented that can be used to identify the combination of fluorescence parameters providing the highest contrast between the affected and unaffected plants or plant segments. Leaves of canola (Brassica napus) and white mustard (Sinapis alba) were exposed to various concentrations of destruxins and images of key fluorescence signals (F 0 , F M , Fp, and of F S ) were captured in a single kinetic experiment. Contrast was quantified within these images between the leaf areas exposed to destruxins and the untreated areas. The highest contrast was found in the image constructed by pixel-to-pixel division of images F 0 by Fp and F 0 by F M . Using the F 0 /F M ratio image, we were able to detect exposure to destruxin concentration as low as approximately 0.05mgl -1 applied to canola leaf and approximately 10mgl -1 when applied to mustard. The detection limits were significantly lower than those obtained by optical microscopy indicating that kinetic chlorophyll fluorescence imaging can be used as a diagnostic tool in screening for varieties with an enhanced resistance to destruxins of Alternaria brassicae.
Present and Future Taxonomic Selectivity in Bird and Mammal Extinctions

We compared the distribution of historical bird and mammal species extinctions across genera and families with the distribution we would expect if these extinctions had occurred at random with respect to taxonomy. We then repeated the comparison for species listed in various categories of threat according to the 1996 Red List of the World Conservation Union. We found the distributions of extinctions and threat classifications to be almost always nonrandom—“selective”—with clustering in certain genera and families. Furthermore, extinctions tended to be clustered in taxa that contain few species; species in smaller genera tended to have higher probabilities of extinction. This tendency was strong for historical extinctions but was reduced or absent for some categories of threat. We attribute this to a change in the causes of extinction whereby predation and introduced species have been joined or superseded by widespread habitat loss. We then assessed the implications of this variable selectivity for the past and likely future losses of genera and families. In most cases, the number of lost taxa rises. Finally, we made predictions about minimum losses of taxa at specific dates in the future and showed that, despite the reduction in some forms of selectivity, we will still lose more taxa than if species extinctions were random.
Nystatin‐enhanced glutathione production by Saccharomyces cerevisiae depends on γ‐glutamylcysteine synthase activity and K+

Glutathione (GSH), an important tripeptide compound, is widely used as a therapeutic and in the food and cosmetic industries. To improve its production yield, we added the antibiotic nystatin to a batch fermentation of Saccharomyces cerevisiae, at different concentrations and at various times. Based on the results that nystatin can effectively stimulate GSH accumulation but at the same time inhibits cell growth, a three‐point addition strategy (0.05 mg/L at 8 h, 0.25 mg/L at 16 h, and 0.5 mg/L at 20 h) was developed to maximize GSH production. As a result, a maximum yield of 237.8 mg/L was obtained, which was by 50.6% higher than without the addition of nystatin. When combining this strategy with cysteine addition, the GSH yield increased to 278.9 mg/L. Subsequently, the γ‐glutamylcysteine synthetase (γ‐GCS) activity and K+ concentration were analyzed to investigate the possible mechanism involved in the increased production. It was found that the nystatin‐induced increase in the GSH yield was associated with a higher γ‐GCS activity and K+ concentration.
The Pneumococcal Polysaccharide-Tetanus Toxin Native C-Fragment Conjugate Vaccine: The Carrier Effect and Immunogenicity

The encapsulated bacteria, as Streptococcus pneumonia, Haemophilus influenzae type b, and Neisseria meningitidis, cause serious morbidity and mortality worldwide. The capsular polysaccharide (PS), which could elicit a weak T cell-independent immune response, is a vital virulence determinant. One of the strategies to improve the PS-specific immunogenicity is to conjugate PS with a nontoxic carrier protein. Tetanus toxoid (TT) and CRM197 are the typical carrier proteins for the PS conjugate vaccines. TT is the inactivated tetanus toxin manipulated with formaldehyde, which suffers from the pollution from residual formaldehyde and the incomplete detoxification. CRM197 has the disadvantage of low-yield purification with the requirement of sophisticated culture conditions. Thus, a novel carrier protein without these disadvantages is highly required. The tetanus toxin native C-fragment (Hc) is safe, low-cost, and highly immunogenic with easy purification, which can act as a promising carrier protein. Pneumococcal serogroups 14 and 23F were major epidemic causes of pneumococcal infections. In the present study, the capsular PSs (PS14 and PS23F) were conjugated with Hc, TT, and CRM197, respectively. TT- and CRM197-based conjugates acted as controls for Hc-based conjugates (PS14-Hc and PS23F-Hc). The structural properties of Hc were not fundamentally changed after conjugated with PS. PS14-Hc and PS23F-Hc could potentiate sound PS-specific antibody levels comparable to the controls. Thus, Hc exhibited a practical carrier effect to help the pneumococcal conjugate vaccines perform good immunogenicities.
A biologically relevant habitat condition index for streams in northern Portugal

1. This study describes the development of an index for assessing stream habitats in northern Portugal at a variety of spatial scales and levels of perturbation. In developing the index, 86 environmental variables, including regional and local ones, were used to reflect the geomorphological characteristics, riverine habitat, and human activities occurring in each basin. 2. Collections of benthic invertebrates were made at each sample site. To reflect the observed variation in assemblages, the streams were separated into two categories: the North-west catchments and the Douro catchments. 3. Multivariate analysis techniques applied to the physical and biological data sets allowed the determination of the relative importance of local and regional environmental descriptors in the discrimination of the invertebrate assemblages. 4. Successive statistical refinement procedures yielded 10 variables, all at the local scale. Variation along disturbance gradients allowed the development of a habitat index through scoring criteria that separated reference sites from stressed sites. 5. The results indicate the reduced impact of catchment factors by a buffering influence probably resulting from the presence of a riparian corridor. Copyright © 2005 John Wiley Sons, Ltd.
Very few sites can reshape the inferred phylogenetic tree

The history of animal evolution, and the relative placement of extant animal phyla in this history is, in principle, testable from phylogenies derived from molecular sequence data. Though datasets have increased in size and quality in the past years, the contribution of individual genes (and ultimately amino acid sites) to the final phylogeny is unequal across genes. Here we demonstrate that removing a small fraction of sites strongly favoring one topology can produce a highly-supported tree of an alternate topology. We explore this approach using a dataset for animal phylogeny, and create a highly-supported tree with a monophyletic group of sponges and ctenophores, a topology not usually recovered. Because of the high sensitivity of such an analysis to gene selection, and because most gene sets are neither standardized nor representative of the entire genome, researchers should be diligent about making intermediate analyses available with their phylogenetic studies. Effort is needed to ensure these datasets are maximally informative, by ensuring all genes are systematically sampled across relevant species. From there, it could be determined whether any gene or gene sets introduce bias, and then deal with those biases appropriately.
Preparation and Physical Properties of Zein-Coated High-Amylose Corn Starch Film

Abstract The objective of this study was to prepare the edible composite films using high-amylose corn starch (HACS) and corn zein and to determine their physical properties. HACS was gelatinized using the specially designed high-pressure container. HACS film containing 20 g sorbitol/100 g as a plasticizer had suitable physical properties. The HACS film coated with corn zein containing 20 g oleic acid/100 g had moderate physical properties and barrier properties.
Control de fuerza en actuadores hidráulicos mediante válvula proporcional de alivio

Con la formulacion del principio de Pascal, se han desarrollado trabajos importantes en el area de la potencia fluida y control. Las variables mas empleadas en este campo son: velocidad, posicion y fuerza; se encuentra sufi ciente literatura al respecto, sobre todo cuando estas variables son tratadas mediante valvulas distribuidoras proporcionales de cuatro vias y tres posiciones como elemento fi nal de control. Estas se comportan muy bien para controlar velocidad y posicion, pero cuando se requiere de un control fi no de fuerza, se hace necesario la inclusion de valvulas proporcionales de alivio. Por esta razon se quiere mostrar en el presente articulo el control de fuerza en actuadores hidraulicos mediante una valvula proporcional de alivio, realizando su caracterizacion y comportamiento de manera experimental. Ademas, se genera un esquema que integra los elementos hidraulicos, la intercomunicacion y adquisicion de datos del sistema con el proposito de regular la fuerza que depende de una carga previamente establecida, por medio de una interfaz entre el sistema de control y los actuadores.
Banks and cross-border capital flows: challenges and regulatory responses

his report was written by the Committee on International Economic Policy and Reform, a non-partisan, independent group of experts, comprised of academics and former government and central bank officials. Its objective is to analyze global monetary and financial problems, offer systematic analysis, and advance reform ideas. The committee attempts to identify areas in which the global economic architecture should be strengthened and recommend solutions intended to reconcile national interests with broader global interests. Through its reports, it seeks to foster public understanding of key issues in global economic management and economic governance. Each committee report will focus on a specific topic and will emphasize longer-term rather than conjunctural policy issues. In this September 2012 report, the committee lays out a framework for cross-border banking flows and for improved regulatory coordination.