Miracle-dz/UniFAR-FTUs huggingface dataset:
A preliminary study of acute responses to clamped alcohol concentration and family history of alcoholism.

BACKGROUND The clamping method of alcohol administration was combined with a battery of dependent measures of frontal lobe brain function, and a novel index of acute adaptation, in a preliminary study in order to explore the paradigm's sensitivity to a familial history of alcoholism (FHA). METHODS Ten family history-positive (FHP) and 10 family history-negative (FHN) adult social drinkers of both genders underwent alcohol clamping. Twenty minutes after the start of an intravenous infusion of alcohol, the breath alcohol concentration was clamped at a target of 60+/-5 mg/dl for 150 min. Initial and adaptive responses to alcohol were assessed using scalar indices of change. One index assessed initial improvements or impairments in brain function after alcohol. The other index assessed acute adaptation (tolerance or sensitization) to alcohol while the brain's exposure to alcohol was held constant. The battery of dependent measures included subjective perceptions, neuropsychological tests, saccadic eye-movement tasks, and event-related potential (ERP) tasks. Effect sizes for FHA were estimated for 10 dependent variables that showed adequate baseline test-retest reliability (r>0.6). RESULTS FHP subjects showed less intense initial responses to alcohol in subjective perceptions, but greater changes in the latency of volitional saccades and ERP P3 components than did the FHN controls. FHP subjects generally showed greater acute tolerance to alcohol than did controls, who showed more instances of acute sensitization at this moderate breath alcohol concentration. Effect sizes for FHA exceeded 0.4 in more than half of the indices. CONCLUSIONS The BrAC clamping paradigm assesses initial and adaptive responses of a battery of behavioral and electrophysiological measures of frontal lobe function to ethanol that appear both reliable and sensitive to FHA.
ESPRIT-Based Carrier Frequency Offset Estimation for OFDM Direct-Conversion Receivers

Over the last years, there has been growing interest in making user terminals more efficient in terms of cost, size, and power consumption. A step forward in this direction is represented by direct-conversion receiver (DCR) architectures, which directly convert the received waveform from the radio frequency (RF) to baseband, thereby avoiding any intermediate frequency (IF) stage. One major issue of DCR devices is the presence of RF impairments, which greatly complicate fundamental receiver functions, including the synchronization task. In this paper we propose a carrier frequency offset (CFO) recovery scheme for OFDM DCRs plagued by frequency-selective In-phase/Quadrature (I/Q) imbalances. Our approach is based on the ESPRIT algorithm and relies on the transmission of a typical OFDM training preamble having a repetitive structure in the time domain. Numerical simulations indicate that the proposed scheme outperforms existing state-of-the-art alternatives at the price of a certain increase of the processing load.
The Protective Effects of Bevacizumab in Bleomycin-Induced Experimental Scleroderma.

BACKGROUND The capillary networks are less dense and have irregular structures in scleroderma. These abnormalities result in lower capillary blood flow causing severe tissue hypoxia, which is a major stimulus for angiogenesis. However, current knowledge about compensatory angiogenesis is ambiguous in scleroderma. Bevacizumab is an inhibitor of vascular endothelial growth factor (VEGF). OBJECTIVES The aim of the present study is to evaluate the protective effects of bevacizumab in bleomycin (BLM)- -induced dermal fibrosis. MATERIAL AND METHODS This study involved 4 groups of Balb/c mice (n = 10 per group). Mice in the control group received 100 μL/day of phosphate-buffered saline (PBS) subcutaneously, while the other 3 groups were given 100 μg/day of BLM (dissolved in 100 μL PBS) subcutaneously, for 4 weeks. Mice in BLM-treated 3rd and 4th groups also received bevacizumab (1 or 5 mg/kg twice a week, intraperitoneally). At the end of the fourth week, all mice were sacrificed and blood and tissue samples were obtained. RESULTS The BLM applications increased the dermal thicknesses, tissue hydroxyproline contents, and α-smooth muscle actin-positive (α-SMA+) cell counts, and led to histopathologically prominent dermal fibrosis. The bevacizumab treatments decreased the tissue hydroxyproline contents and dermal thicknesses, and these improvements were more prominent at doses by which α-SMA+ cell counts were markedly decreased, in the BLM-injected mice. CONCLUSIONS In our study, inhibition of VEGF with bevacizumab treatments prevented the BLM-induced dermal fibrosis suggesting that VEGF expression contributes to the pathogenesis of scleroderma.
IoT fall detection system for the elderly using Intel Galileo development boards generation I

In today society there has been an increase in the number of elderly people that can fend for themselves. However, there are certain risks related to age such as falls, blood pressure or heart problems among others, that can result in serious consequences to the person. The objective of this study is the development of a system oriented IoT, which can be acquired by the low income population, allowing any member of the family to do a remote following up. One of the most serious problems is the falls. For this reason we started developing a module that can detect falls by using accelerometers and gyroscopes in this first stage, as a part of the daily elderly control integral system using the “Intel Galileo Gen I” development board. Selection criteria of the sensors used for this purpose together with corrections reading and data processing are described, because working with a sensor MPU6050 with Intel Galileo Gen I differs respect to other platforms. An analysis on different fall detection algorithms is done; false positives are discarded applying notifications alarms thus acquiring trustworthy data for their processing.
Using a Delphi method and the Analytic Hierarchy Process to evaluate the search engines: A case study on Chinese search engines

Purpose – The purpose of this study is to develop an evaluation criteria system for search engines using the Delphi method and the analytic hierarchy process, and to conduct an empirical study on Chinese search engines to verify it. This is because the evaluation criteria in current research rarely considers expert opinions and experience, and seldom calculates the weight of each criterion by quantitative methods.Design/methodology/approach – Expert investigation of the web‐based Delphi method was employed to develop the evaluation criteria, and the analytic hierarchy process based on an exponential scale was adopted to calculate the weight of each criterion. An empirical study was designed to test the evaluation criteria system. A total of 12 study participants were invited to evaluate six popular Chinese search engines by means of e‐mail questionnaires. All the calculation processes were executed automatically by Java programming.Findings – The indexing structure and search method were the core criteria.
A Stochastic Method of Tracking a Vocal Performer

Automated accompaniment systems are computer systems that "play along" with a solo musician or a group of musicians when given the score for a piece of music. These systems must be able to "listen" to the live musicians by tracking their progress through the score in real-time. Accurate tracking of vocal performers (as opposed to instrumentalists) is a particularly challenging case. In this paper, we present a tracking method based upon a statistical model of vocal performances. This technique incorporates both information obtained from real-time signal processing of a performance (such as fundamental pitch) and information describing the performer's movement through the score (namely tempo and elapsed time). We present a description of how this model is incorporated as part of a system currently used to accompany vocal performers. We provide a preliminary evaluation of its ability to estimate score position of a performer.
Target Costing Implementation in Thailand

The purpose of this study is to explore the role of target costing in managing product costs in Thailand. It is seen as a process that can significantly improve new product development considering the customer requirement, incorporates earlier supplier involvement and concurrent engineering, utilizes cross-functional teams. Unlike previous studies, which have focused on Japanese firms, or used single case studies, this paper uses the findings from case studies of 8 organizations of which actively engaged in the target costing process. Our findings illustrated the fact that target costing is used as a tool to create a good or service especially the business on B2B business model that both desirable and affordable to customer and in the meantime profitable to the producing organizations.
Familial aggregation of female sexual orientation.

OBJECTIVE The purpose of this study was to determine whether female homosexuality is familial and whether it is cofamilial with male homosexuality. METHOD Subjects included 84 homosexual and 79 heterosexual female probands recruited through newspaper advertisements. Probands were asked about their siblings' sexual orientations and were asked for permission to contact siblings to confirm their reports. RESULTS The authors were able to contact 60% of eligible siblings, and the information they provided about their sexual orientations confirmed that probands' reports were highly accurate. Homosexual probands had a significantly higher proportion of homosexual sisters according to four criteria for rating siblings' sexual orientations. Homosexual probands also had a higher proportion of homosexual brothers; however, this difference was not significant. CONCLUSIONS Female homosexuality appears to be familial. Further research is required to resolve the question of whether female and male homosexuality are cofamilial.
Validation of multiple origin ases conflicts through bgp community attribute

Recent measurements show that a single IP address prefix often appears to originate from multiple ASes (Multiple Origin AS, or MOAS). MOAS can be due to either legitimate Zhao/Mankin/Massey/Pei/Wang/Wu/Zhang Page 1 INTERNET-DRAFT 13 November 2001 operational need or faults. This document defines a new BGP Community to distinguish valid MOAS from faults.
Long-term gait deviations in anterior cruciate ligament-reconstructed females.

PURPOSE Little is known of the potential long-term gait alterations that occur after an anterior cruciate ligament (ACL) reconstruction. In particular, variables, such as impact loading, which have been previously associated with joint deterioration, have not been studied in walking and running after an ACL reconstruction. The purpose of this study was to define the alterations in impact forces, loading rates, and the accompanying sagittal plane kinematic and kinetic mechanics at the time of impact between the ACL-reconstructed group and a healthy control group. METHODS Forty females (20 with ACL reconstruction and 20 controls) participated in the study. An instrumented gait analysis was performed on all subjects. Between-group and between-limb comparisons were made for the initial vertical impact force, loading rate, and sagittal plane knee and hip angles as well as moments. RESULTS During walking and running, the ACL cohort had significantly greater initial vertical impact force (P = 0.002 and P = 0.001, respectively) and loading rates (P = 0.03 and P = 0.01, respectively), as well as a smaller knee extensor moment and hip angle during walking (P = 0.000 and P = 0.01, respectively). There was a trend toward a smaller knee moment and hip angle during running (P = 0.08 and P = 0.06, respectively) as well as a larger hip extensor moment during walking (P = 0.06) in the ACL group. No differences were found for hip extensor moment during running and for knee angles between groups during walking or running. Lastly, no between-limb differences were found for any variable. CONCLUSIONS Gait deviations such as elevated impact loading and loading rates do not resolve long term after an individual has resumed previous activity levels and these may contribute to the greater risk of early joint degeneration in this population.
On the detectability of CMOS floating gate transistor faults

This paper focuses on the detectability of defects causing the gates of transistors in CMOS integrated circuits to float (open), i.e., on floating gate transistor (FGT) faults. Such faults are known to occur in practice. It is increasingly important to consider their detection to meet high quality requirements for circuits fabricated in deep submicrometer technologies. We focus on the detectability of FGT faults by the standard voltage- and current-based production test strategies that we refer to as static voltage (SV), dynamic voltage (DV), and static current (SC) test strategies. We demonstrate how the behavior of the devices caused by FGT faults depends on two classes of technological and topological parameters: the predictable and unpredictable parameters. We show that an FGT fault can induce abnormal logic values, additional delays, or increased power supply current. We introduce the concept of a detectability interval, i.e., the range of values an unpredictable parameter may assume that one allows for the fault detection using a specific test strategy. We illustrate how the detectability intervals for the SV and DV strategies complement that of the SC strategy. In addition, a new test scheme that results in an increased SC detectability of FGT faults is developed. Finally, we demonstrate the effects of initial trapped charges and the effects of coupling to surrounding metal on the detectability intervals of each of the test strategies.
A Social Networking-Based Access Control Scheme for Personal Content

Personal media continues to drive the growth of home computing and consumer electronics. Equipped with various appliances, home users continue to create enormous quantities of photos, home videos, song collections, or blog pages. This new landscape has led to new challenges facing home users – managing their personal data, searching it to find objects of interest, and sharing it with family and friends. These challenges have motivated the emergence of new class of web sites and applications such as MySpace, Flickr, YouTube, and Google calendar to help users manage and share their personal content online. However, there is a mismatch between people’s needs for sharing personal content and what today’s online applications offer. Most sharing sites restrict their users to a specific type of content. While sharing personal content warrants the need for restricting access, most sites (e.g., Flickr, YouTube) offer only two very simple access control policies. People can either enumerate all the site-specific userids who should have access or they can make the content publicly available to anyone. In addition, users must now create and maintain several copies of their social network: one for each online site. They must ask their friends and families to register userids on each site serving their personal content. Our work presents a social networking-based access control scheme suitable for online sharing of personal media. Our goals are:
Cholinergic Sensitivity of the Denervated Canine Heart

SUMMARY We determined whether the extrinsically denervated heart becomes supersensitive to acetylcholine (ACh) and nicotine (NIC). Fifteen mongrel dogs were subjected to total extrinsic cardiac denervation. The negative inotropic responses of their hearts were compared with those of 15 control dogs with respect to ACh (0.005-1.0 pig) and NIC (10-300 fig) administered intracoronary. All dogs were placed on cardiopulmonary bypass, and atrial and ventricular contractility were evaluated using a four-chamber, isovolumic technique. The denervated hearts showed no detectable supersensitivity to ACh. Because the effects of ACh at the doses used are almost completely on the decentralized cardiac muscle cells, the results indicate that the cardiac muscle is an exception to the increased sensitivity usually produced by decentralization. When the positive inotropic effects of NIC were blocked by practolol in the control hearts, the negative inotropic effects of the intrinsic parasympathetic neurons (IPN) are seen clearly. These intrinsic neural elements are specifically activated by NIC. The denervated atria and ventricles displayed NIC dose-response curves that consistently were shifted to the left when compared to control animals after 0,-blockade. These results indicate the IPN, which are denervated by the surgical procedure, do become more sensitive to NIC. The increases in sensitivity to NIC were between 2-and 6-fold, comparable to the increased sensitivity to norepinephrine observed in denervated hearts. The postjunctional IPN supersensitivity probably occurs as a result of spreading of nicotinic receptors on the ganglion cell membrane.
Male and Female Chromosomes in Genetic Algorithms

Evolutionary algorithms work on randomly generated populations, which are converged over runs toward the desired optima. Randomly generated populations are of different qualities based on their average fitness values. In many cases switching all bits of a randomly generated binary individual to their opposite values might quickly produce a better individual. This technique increases diversity among individuals in the population and allows exploring the search space in a more rigorous way. In this research the effect of such operation during the initialization of the population and crossover operator has been investigated. Experimentation with 44 test problems in 2200 runs showed that this technique can facilitate producing better individuals on average in around 32% of cases.
Application of Stakeholder Theory to the Quantity and Quality of Australian Voluntary Corporate Environmental Disclosures

This study provides a comprehensive, integrated theory for explaining social responsibility disclosures. The relevant theory applied is Ullmann's (1985) three dimensional model of social responsibility disclosure. The research question asked is: Can Ullmann's stakeholder theory be operationalized to help explain the quantity and quality of environmental disclosures in annual reports in a voluntary reporting setting? Quantity is measured by the number of sentences devoted to environmental issues reported in the annual report while quality of disclosures is measured by a index scored by users of financial statements with financial reporting qualifications. Both quantity of disclosure and quality of disclosure are highly correlated. The sample consists of 102 of the largest companies listed on the Australian Stock Exchange. Ordinary least squares regression is used to determine if variables selected to measure stakeholder power, strategic posture and economic performance are significant in explaining the quantity and quality of environment disclosures in annuals reports. The stakeholder power dimension of Ullmann's framework measured by shareholder, regulator and lobby groups is significant in explaining environmental disclosures. The strategic posture dimension of Ullmann's model measured by content of the mission statement and existence or otherwise of environmental or social responsibility committees also find strong statistically significant support in the results. The third dimension of economic performance is not supported by the results. Consistent with prior studies, size is found to be a significant predictor of disclosure practices.
On Leaving Corporate Executives Naked, Homeless and Without Wheels: Corporate Fraud, Equitable Remedies, and the Debate Over Entity Versus Individual Liability

There is a lively debate about the relative merits of entity versus individual liability in cases involving securities fraud. After reviewing this debate in the context of both private securities litigation and SEC enforcement, this paper considers whether the legal tools available against individual executives are adequate, and if not, what changes might be made. The main focus is on equitable remedies, especially rescission and restitution, under both state and federal law. As to the former, Vice Chancellor Strine's opinion in In re Healthsouth offers an interesting template, although there are limits on the usefulness of derivative suits to police aggressively in this area. Federal law probably offers the more powerful tools, which could be used more effectively than they are at present.
Rapid facial reactions in response to happy and angry expressions in 7‐month‐old infants

Humans rapidly and spontaneously activate muscles in the face when viewing emotional facial expressions in others. These rapid facial reactions (RFRs) are thought to reflect low-level, bottom-up processes, and are theorized to assist an observer to experience and share the affect of another individual. It has been assumed that RFRs are present from birth; however to date, no study has investigated this response in children younger than 3 years of age. In the present study, we used facial electromyography (EMG) to measure corrugator supercilii (brow) and zygomaticus major (cheek) muscle activity in 7-month-old infants while they viewed happy and angry facial expressions. The results showed that 7-month olds exhibited greater zygomaticus activity in response to happy expressions than angry expressions, however, we found no evidence of differential corrugator muscle activity.
THE INFLUENCE OF CONSUMER BEHAVIOR ON PURCHASE DECISION XIAOMI CELLPHONE IN MANADO

The growing need and rapid development of technology in the era of globalization, free markets, and increasingly fierce competition made ​​the company create products to meet the diverse needs of consumers especially in mobile phone industry. The purpose of this research is to analyse the influence of culture, social, personal, and psychological factors towards consumer purchase decision on Xiaomi cellphone in Manado partially and simultaneously. Sample determined for 80 consumers. Tools of analysis using Multipler Regression, hypothesis test using F test and T test. The result of research shows that social, culture, personal, and psychological simultaneously have significant influence towards consumer purchase decision. In partially social factor have significant influence towards consumer purchase decision, while culture, personal, and psychological partially do not have significant influence toward consumer purchase decision . The management of Xiaomi should expand their strategic marketing sales via offline in order to influence the cultural, personal, and psychological factor, thus increasing their sales in Manado. Keywords : culture, personal, psychological, purchase decision, social
Restructuring and reforms in the Korean banking industry

The Korean banking industry has undergone substantial structural reforms since the 1997 financial crisis. A number of banks merged or exited, and foreign banks were permitted to enter the banking industry. Perhaps most significantly, there have been fundamental changes in the behavior of banks; they are now focusing much more on profitability and competitiveness than they did in the past. They are also assuming an increasingly important role as comprehensive asset managers.