Miracle-dz/UniFAR-FTUs huggingface dataset:
Macro Talent Management in Emerging and Emergent Markets

Macro Talent Management in Emerging and Emergent Markets is the first book to focus specificially on country-level activities that aimed at attracting, developing, mobilizing, and retaining top talent for economic success. The book serves as a guide that orients the reader toward activities that increase their country’s global competitiveness, attractiveness, and economic development through strategic talent management. This book brings together leading experts from around the world to address such issues as cross-border flows of talent, diaspora mobility, knowledge flows, global labour markets, and policies. The book is structured in three parts: part 1 covers emerging markets, part 2 emergent markets, and part 3 pan-national themes such as migration and clusters. Bringing together research from the fields of human resource management, international business, economic geography, comparative international development, and political economy, this is a definitive, comprehensive treatment of the topic aimed at advanced students and practitioners.
Kant et Smith critiques de la philosophie morale de Hume

Malgre tout ce qui les distingue, la philosophie morale de Kant et celle de Smith ont pour point commun de se poser toutes les deux explicitement en critiques des positions de Hume. Ces critiques portent sur le meme point, la facon dont Hume definit le concept de generalite. De la resultent des theses paralleles : Kant et Smith proposent une conception formelle de la morale, debouchant sur l'idee d'un tribunal interieur et sur celle d'un ideal moral. Plais jusqu'ou ce parallele est-il pertinent ?
Evidence based medicine: what it is and what it isn't. 1996.

After training in internal medicine, nephrology and epidemiology, Dave Sackett's first career (age 32) was as the founding Chair of Clinical Epidemiology & Biostatistics at McMaster. In his second career he began to design, execute, interpret, monitor, write and teach about randomized clinical trials, an activity that continues to the present, some 200 trials later. His third career was dedicated to developing and disseminating "critical appraisal" strategies for busy clinicians, and ended when he decided he was out of date clinically and returned (at age 49) to a two-year "retreading" residency in General Internal Medicine. His fourth career (and the only one he didn't enjoy) was as Physician-in-Chief at Chedoke-McMaster Hospitals. His fifth career was as Head of the Division of General Internal Medicine for Hamilton and Attending Physician at the Henderson General Hospital. When a chair was created for him at Oxford, he took up his sixth career as foundation Director of the NHS R&D Centre for Evidence-Based Medicine, Consultant on the Medical Service at the John Radcliffe Hospital, and Foundation Co-Editor of Evidence-Based Medicine. At present he is Director of the Trout Research & Education Centre at Irish Lake in Canada, where he reads, researches, writes and teaches about clinical-practice research.
Towards a theory of quality management: an integration of strategic management, quality management and project management

Despite the potential benefits of TQM, its application in healthcare organisations encountered difficulties. The main purpose of this study is to develop a model of quality management for healthcare organisations. Thirty quality management experts were approached by using a Delphi method to specify the components of an appropriate quality management model. The core research led to the development of a context-specific model of quality management for healthcare organisations. It includes creating the organisation’s long-term quality goals and objectives related to employees, customers, suppliers, society and organisation, developing strategies and action plans to achieve these objectives, providing the necessary education and training, adopting cultural change, and then allocating resources to implement the action plans.
Exploiting Higher Kinematic Performance - Using a 4-Legged Redundant PM Rather than Gough-Stewart Platforms

It is believed that Gough and Whitehall (1962) first introduced parallel robots with an application in tire-testing equipments, followed by Stewart (1965) , who designed a parallel mechanism to be used in a flight simulator. With ever-increasing demand on the robot’s rigidity, redundant mechanisms, which are stiffer than their non-redundant counterparts, are attracting more attention. Actuation redundancy eliminates singularity, and greatly improves dexterity and manipulability. Redundant actuation increases the dynamical capability of a PM by increasing the load-carrying capacity and acceleration of motion, optimizing the load distribution among the actuators and reducing the energy consumption of the drivers. Moreover, it enhances the transmission characteristics by increasing the homogeneity of the force transmission and the manipulator stiffness (Yi et al., 1989). From a kinematic viewpoint, redundant actuation eliminates singularities (Ropponen & Nakamura, 1990) which enlarge the usable workspace, as well. The kinematic analysis on general redundantly actuated parallel mechanisms was investigated by Muller (2005). A number of redundantly full-actuated mechanisms have been proposed over the years and some of them which are more significant are listed in this section. The spatial octopod, which is a hexapod with 2 additional struts, is one of them (Tsai, 1999). A 5-DOF 3-legged mechanism was proposed by Lu et al. (2008), who studied its kinematics, statics, and workspace. Staicu (2009) introduced a new 3-DOF symmetric spherical 3-UPS/S parallel mechanism having three prismatic actuators. As another work of Lu et al. (2009), they introduced and used 2(SP+SPR+SPU) serial–parallel manipulators. Wang and Gosselin (2004) addressed an issue of singularity and designed three new types of kinematically redundant parallel mechanisms, including a new redundant 7-DOF Stewart platform. They concluded that such manipulators can be used to avoid singularities inside the workspace of non-redundant manipulators. Choi et al. (2010) developed a new 4-DOF parallel mechanism with three translational and one rotational movements and found this mechanism to be ideal for high-speed machining.
Influence of Prestorage Incubation on the Hatchability of Guinea Fowl Eggs Stored for Fourteen Days.

Abstract This study was conducted to determine the effects of different prestorage incubation (PRESI) times of 0, 3, 6 and 9 h on the hatchability of guinea fowl eggs stored for 14 d. A total of 80 eggs were assigned to each of the four PRESI treatments. PRESI-3h, PRESI-6h and PRESI-9h eggs were placed in an incubator at 37.5°C and 65% relative humidity for 3, 6 and 9 h, respectively, before storage with the PRESI-0h (control) eggs for 14 d at 18°C. After 14 d storage period the eggs were incubated at 37.5°C and 65% relative humidity. After 30d incubation period, the total number of eggs hatched (keets) were counted and all unhatched eggs opened to determine fertility. Hatchability data were analyzed using General linear Models of SAS and the model included fixed effects of PRESI treatments. The results indicated that PRESI treatment had an influence on the hatchability of both fertile and set eggs. PRESI-6h resulted in higher hatchability of both fertile and set eggs compared to the control group. There were however, no significant differences in hatchability of fertile eggs and hatchability of set eggs between the PRESI-9h and the control groups. These results indicate that PRESI-6h greatly reduces embryonic mortality resulting in higher hatchability compared to the other groups. It therefore appears that PRESI-6h could be used as a strategy of improving the hatchability of guinea fowl eggs stored for 14d.
Investigation of tunneling current and local contact potential difference on the TiO2(110) surface by AFM/KPFM at 78 K

We propose a new multi-image method for obtaining the frequency shift, tunneling current and local contact potential difference (LCPD) on a TiO2(110) surface with atomic resolution. The tunneling current image reveals rarely observed surface oxygen atoms contrary to the conventional results. We analyze how the surface and subsurface defects affect the distribution of the LCPD. In addition, the subsurface defects are observed clearly in the tunneling current image, in contrast to a topographic image. To clarify the origin of the atomic contrast, we perform site-dependent spectroscopy as a function of the tip–sample distance. The multi-image method is expected to be widely used to investigate the charge transfer phenomena between the nanoparticles and surface sites, and it is useful for elucidating the mechanisms of catalytic reactions.
Tuberculin skin testing and the HIV epidemic.

Tuberculosis (TB) cases in the United States have steadily increased in number since 1985. Much of this increase appears attributable to the human immunodeficiency virus (HIV)/ acquired immunodeficiency syndrome (AIDS) epidemic, with TB occurring both in those HIV-infected persons with latent as well as recently acquired TB infection. 1 Infection with HIV now is recognized as the most important risk factor for progression from tuberculous infection to active disease. The annual risk of disease in persons dually infected with TB and HIV is 7% to 10%, considerably greater than the 10% lifetime risk in HIV-uninfected tuberculin reactors. 1,2 See also p 369. As a result of the increasing TB morbidity associated with HIV, screening for tuberculous infection now is recommended practice for all patients with HIV infection as well as patients in drug treatment centers, sexually transmitted disease clinics, and HIV/AIDS clinics. 1 Treatment of TB-infected persons with isoniazid can
Coating bone‐like apatite onto organic substrates using solutions mimicking body fluid

Bone‐like apatite is a carbonated hydroxyapatite with a small crystallite and low crystallinity. The formation of a layer consisting of bone‐like apatite is an essential condition for bioactive materials to achieve direct bonding with living bone. A bone‐like apatite layer can be formed on the surface of organic substrates in a solution mimicking a body fluid when some functional groups are introduced to organic substrates. This process is a biomimetic process because a simulated body fluid and related solutions are used to deposit bone‐like apatite crystals and promote crystal growth. Coating of bone‐like apatite layers through biomimetic processes has received much attention in the fabrication of novel composites with bone‐bonding properties, i.e. bioactivity, and mechanical properties analogous to those of living bone tissues. This paper reviews recent developments in coating with bone‐like apatite layers using biomimetic processes. Copyright © 2007 John Wiley & Sons, Ltd.
Blood contact activation: pathophysiological effects and therapeutic approaches

a nonphysiologic manner. Perfusion is conducted using heparinization, haemodilution, pulsatile or nonpulsatile flow, and some degree of hypothermia. Oxygenation is achieved using membrane or bubble oxygenators. Significant clinical morbidity is relatively unusual, although this owes more to the body’s ability to compensate for the damaging effects of CPB than to extracorporeal circulatory perfection. CPB poses significant pathophysiological effects, principally from four areas; haemodynamics and perfusion,4-16 gaseous exchange,17-21 hypothermia and acid-base regulation22-28 and, finally, blood contact activation. Contact activation is caused when the formed
Downregulation of microRNA-206 is a potent prognostic marker for patients with gastric cancer

Background MicroRNA-206 (miR-206), as a homolog of miR-1, plays important roles in tumorigenesis and tumor progression of various human malignancies, including breast cancer, endometrial endometrioid carcinoma, rhabdomyosarcoma, glioma, lung cancer, and laryngeal cancer. However, its involvement in gastric cancer has remained unclear. Aim To examine the expression patterns and clinical implications of miR-206 in gastric cancer. Materials and methods Quantitative RT-PCR was performed to evaluate the expression levels of miR-206 in 98 pairs of gastric cancer and normal adjacent mucosa. In addition, the clinicopathologic significance and the prognostic value of miR-206 expression were further determined. Results At first, miR-206 expression was significantly downregulated in gastric cancer tissues when compared with normal adjacent mucosa (P<0.001). Next, tumors with low miR-206 expression had a greater extent of lymph node metastasis (P=0.01), presence of venous invasion (P=0.008), and hematogenous recurrence (P=0.01), and were at a worse stage (P=0.03) than the tumors with a high miR-206 expression. Then, the gastric cancer patients with a low miR-206 expression had shorter overall survival than those with a high miR-206 expression (P=0.02). Furthermore, multivariate analysis showed that miR-206 expression was an independent prognostic factor for patients with gastric cancer. Conclusion Our results strongly suggest that the downregulation of miR-206 was significantly correlated with tumor progression and may be a potent prognostic marker of gastric cancer. miR-206 might serve as a promising therapeutic target for the treatment of this cancer.
Tolerability and Clinical Outcome of Coseasonal Treatment with Escherichia coli Strain Nissle 1917 in Grass Pollen-Allergic Subjects

Background: Nonpathogenic Escherichia coli strain Nissle 1917 (EcN) has immunomodulatory properties and can act on different cells which are important for the allergic immune response. Herein, we investigated the efficacy and tolerability of EcN in subjects with grass pollen-dependent allergic rhinoconjunctivitis. Methods: Grass pollen-allergic subjects were randomly allocated to receive EcN in a double-blind, placebo-controlled manner. The treatment was performed from 2 months before onset until the end of one grass pollen season (in total: 6 months). The clinical symptom score and the intake of symptomatic medications were assessed. A skin prick test and grass pollen-specific immunoglobulin (Ig) E and IgA were evaluated before and after treatment. Results: Our results show that coseasonal treatment with EcN in grass pollen-allergic subjects was not superior to placebo as assessed using the symptom-medication score (p = 0.257). Interestingly, an increase [median (range)] in grass pollen-specific IgA was detectable in the EcN group [20,556 LU/ml (1,812-60,800)] versus placebo [5,246 LU/ml (944-50,467)] (p = 0.048). Conclusions: The results indicate that 6 months of coseasonal nonspecific immunomodulation by EcN is not sufficient to achieve clinical efficacy in grass pollen-allergic subjects. Future approaches in which such immunomodulators are combined with an allergen-specific protocol might enhance the clinical efficacy of the allergen-specific treatment.
Platelet-derived Growth Factor Inhibits Insulin Stimulation of Insulin Receptor Substrate-1-associated Phosphatidylinositol 3-Kinase in 3T3-L1 Adipocytes without Affecting Glucose Transport*

Phosphatidylinositol 3-kinase (PI3K) activation is necessary for insulin-responsive glucose transporter (GLUT4) translocation and glucose transport. Insulin and platelet-derived growth factor (PDGF) stimulate PI3K activity in 3T3-L1 adipocytes, but only insulin is capable of stimulating GLUT4 translocation and glucose transport. We found that PDGF causes serine/threonine phosphorylation of insulin receptor substrate 1 (IRS-1) in 3T3-L1 cells, measured by altered mobility on SDS-polyacrylamide gel, and this leads to a decrease in insulin-stimulated tyrosine phosphorylation of IRS-1. The PI3K inhibitors wortmannin and LY294002 inhibit the PDGF-induced phosphorylation of IRS-1, whereas the MEK inhibitor PD98059 was without a major effect. PDGF pretreatment for 60–90 min led to a marked 80–90% reduction in insulin stimulatable phosphotyrosine and IRS-1-associated PI3K activity. We examined the functional consequences of this decrease in IRS-1-associated PI3K activity. Interestingly, insulin stimulation of GLUT4 translocation and glucose transport was unaffected by 60–90 min of PDGF preincubation. Furthermore, insulin activation of Akt and p70s6kinase, kinases downstream of PI3K, was unaffected by PDGF pretreatment. Wortmannin was capable of blocking these insulin actions following PDGF pretreatment, suggesting that PI3K was still necessary for these effects. In conclusion, 1) PDGF causes serine/threonine phosphorylation of IRS-1, and PI3K, or a kinase downstream of PI3K, mediates this phosphorylation. 2) This PDGF-induced phosphorylation of IRS-1 leads to a significant decrease in insulin-stimulated PI3K activity. 3) PDGF has no effect on insulin stimulation of Akt, p70s6kinase, GLUT4 translocation, or glucose transport. 4) This suggests the existence of an IRS-1-independent pathway leading to the activation of PI3K, Akt, and p70s6kinase; GLUT4 translocation; and glucose transport.
STOCK PRICE BEHAVIOR AROUND CUM-DIVIDEND DATE OF INDONESIA BLUE CHIPS STOCKS

This study tests whether there are significant stock prices changes around the cum-dividend date. In particular, it examines the stock price movement of two days before and two days after the cum-dividend date. It uses an event study methodology. The population of this study are all companies in the LQ45 listed at Indonesia stock exchange for the year 2017 and the sample consists of 38 companies. Abnormal return is measured using the single index model. Results show that there are no significant abnormal returns around the cum-dividend date. In addition, there is no significant abnormal return difference between two days before and two days after the cum-dividend date. The implication of the reported findings is that investors may not obtain significant positive abnormal returns using a cum-dividend date as the trading strategy.
[Peritoneal fluid iron levels in women with endometriosis].

AIM Endometriosis is characterized by a cyclic hemorrhage within the peritoneal cavity. Accumulating data suggests that iron homeostasis in the peritoneal cavity may be disrupted by endometriosis. The aim of our study was to evaluate iron levels in peritoneal fluid (PF) of women with and without endometriosis. MATERIAL AND METHODS Seventy-five women were studied: 50 women with endometriosis and, as a reference group, 25 patients with functional follicle ovarian cysts. Iron concentrations in the PF were measured using a commercially available colorimetric assay kit. RESULTS Iron concentrations were significantly higher in PF from women with endometriosis as compared to the reference group. Patients with stages III/IV endometriosis had significantly higher PF iron concentrations than women with stages I/II of the disease. CONCLUSIONS Disrupted iron homeostasis in the peritoneal cavity of women with endometriosis plays a role in the pathogenesis of the disease.
Vestibular syndromes in the roll plane: Topographic diagnosis from brainstem to cortex

Central vestibular syndromes may be classified according to the three major planes of action of the vestibuloocular reflex, secondary to a lesional tone imbalance in either the horizontal yaw plane or the vertical pitch or roll plane. The clinical signs, both perceptual and motor, of a vestibular tone imbalance in the roll plane are ocular tilt reaction (OTR), ocular torsion, skew deviation and tilts of the perceived visual vertical (SVV). Either complete OTR or skew torsion without head tilt indicates a unilateral peripheral deficit of otolith input or a unilateral lesion of graviceptive brainstem pathways from the vestibular nuclei (crossing midline at the pontine level) to the interstitial nucleus of Cajal (INC) in the rostral midbrain. SVV tilts are the most sensitive sign of a vestibular tone imbalance in roll and occur with peripheral or central vestibular lesions from the labyrinth to the vestibular cortex. All tilt effects, perceptual, ocular motor and postural, are ipsiversive (ipsilateral eye undermost) with unilateral peripheral or pontomedullary lesions below the crossing of the graviceptive pathways. All tilt effects are contraversive (contralateral eye undermost) with unilateral pontomesencephalic brainstem lesions and indicate involvement of the medial longitudinal fasciculus or the rostral midbrain (INC). Unilateral lesions of vestibular structures rostral to the INC typically manifest with deviations of perceived vertical without concurrent eye–head tilt. OTR in unilateral paramedian thalamic infarctions indicates simultaneous ischemia of the paramedian rostral midbrain including the INC. Unilateral lesions of the posterolateral thalamus can cause thalamic astasia and moderate ipsiversive or contraversive SVV tilts, thereby indicating involvement of the vestibular thalamic subnuclei. Unilateral lesions of the parietoinsular vestibular cortex cause moderate, mostly contraversive SVV tilts. An SVV tilt found with monocular but not with binocular viewing is typical for a trochlear or oculomotor palsy rather than a supranuclear graviceptive brainstem lesion.
Convergence on interneurones mediating the reciprocal Ia inhibition of motoneurones. I. Disynaptic Ia inhibition of Ia inhibitory interneurones.

Interneurones identified as mediating the disynaptic reciprocal Ia inhibition of motoneurones (referred to as "Ia inhibitory interneurones") were recorded in the lumbar spinal cord of the cat. It was revealed that the Ia inhibitory interneurones themselves receive disynaptic Ia inhibition. The muscles from which this inhibition is evoked are strictly antagonistic to those supplying their Ia excitation. Similar to the Ia inhibition in motoneurones the Ia inhibition in the Ia inhibitory interneurones is decreased when preceded by an antidromic stimulation of ventral roots. Furthermore, transmission of Ia inhibition to the Ia inhibitory interneurones is facilitated from ipsilateral and contralateral primary afferents as well as several supraspinal pathways analogous to earlier findings for the Ia inhibition of motoneurones. The pattern and control of the Ia inhibition of motoneurones and of Ia inhibitory interneurones display so striking similarities that it is suggested that identical interneurones are responsible. The conclusion thus emerges that "opposite" Ia inhibitory interneurones (i.e. interneurones monosynaptically connected to antagonistic muscles) are mutually inhibiting each other. The functional significance of this organization is discussed.
Study on the utility model and utility equilibrium of resource service transaction in cloud manufacturing

As a new service-oriented network manufacturing model, cloud manufacturing (CMfg) can accelerate the transformation from production-oriented to service-oriented manufacturing. Study of resource service transaction (RST) is one of the key issues that deciding the practical application of CMfg. In this study, the comprehensive utility models considered the revenue, time, and reliability for the three sides, i.e., resource service provider (RSP), resource service demander (RSD), and resource service agent (Agent) in the RST process in CMfg under the decentralized decision-making condition are first established, respectively. Then the comprehensive utility model for the RST chain (RSTC) of “multiple RSP-one Agent-multiple RSD” under the centralized decision-making condition is proposed and discussed. The existence of utility equilibriums between RSP and Agent, Agent and RSD are proved in the optimal decision of the RSTC under the decentralized decision-making condition.