Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative synergistic activity of cefoperazone, cefotaxime, moxalactam, and carbenicillin, combined with tobramycin, against Pseudomonas aeruginosa

A broth dilution checkerboard synergy assay was used to assess the activity of cefoperazone, cefotaxime, moxalactam, and carbenicillin, in combination with tobramycin, against 38 strains of Pseudomonas aeruginosa. Synergy occurred significantly more often (P less than 0.001) when tobramycin was combined with cefotaxime (63%) than when it was combined with carbenicillin (26%), cefoperazone (21%), or moxalactam (18%). Of the 25 synergistically inhibited strains, the combination cefotaxime-tobramycin was synergistic against 24 and was the only synergistic combination against 10. Of six strains initially resistant to cefotaxime, five were susceptible to this agent (minimum inhibitory concentration, less than or equal to 32 micrograms/ml) when it was combined with tobramycin. Clinical trials are needed to determine the therapeutic efficacy of cefotaxime-aminoglycoside combinations in the treatment of serious Pseudomonas infections.
The Effects of the Threats on the Auditor’s Independence

This study aims at identifying the effects of threats on the auditor’s independence of mind and appearance. Descriptive statistics measurements and analytical statistics (Paired samples test and one Way ANOVA test) are used to analyze the responses of 65 respondents from Jordanian auditors, and to test the hypotheses of the study. They represent 37 % of auditors who registered in 189 Auditing firms in Jordan. The researcher found that threats (Self- interest threats, Self- review threats, Advocacy threats, Familiarity or intimacy threats, and Intimidation threats) affect the auditor’s independence of mind and appearance, and the variables of speciality and experience don’t have an effect in the auditor’s awareness of the importance of the effects of threats on his independence. The study recommends that auditors should know the effects of threats on auditor’s independence, and should abide with the rules of professional behavior, and exercise the suitable defensive procedures against these threats.
Aalborg Universitet Sleep Modes for Enhanced Battery Life of 5 G Mobile Terminals

In addition to higher data rates and lower latency the 5G Radio Access Technology concepts are targeting to provide better battery life for mobile broadband and Machine Type Communication users. In this overview paper we analyze how microsleep, Discontinuous Reception and Transmission, and a wake-up receiver concept can be combined to enhance the battery life of 5G mobile terminals. Due to the short and pipelined 5G frame structure microsleep provides 20 % energy savings as compared to LTE. The Discontinuous Reception and Transmission modes also benefit from the new frame structure leading to faster connection setup and up to 80 % lower energy consumption depending on the traffic type. Finally we estimate that the wake-up receiver concept, when adapted to scheduled and cellular communication, can provide 90 % lower energy consumption and ensure a predictable and consistent latency.
Concurrent chemoradiotherapy with carboplatin and uracil–ftegafur in patients with stage two (T2 N0 M0) squamous cell carcinoma of the glottic larynx

This study aimed to evaluate the efficacy and toxicity of concurrent chemoradiotherapy as a primary treatment modality for larynx preservation in patients with stage two squamous cell carcinoma (SCC) of the glottic larynx. Between February 2000 and August 2003, a total of 20 patients received concurrent chemoradiotherapy. Carboplatin was given intravenously once a week during the period of radiotherapy. The weekly carboplatin dose was based on the area under the curve 1 to 1.25. Uracil–ftegafur (UFT) was given in a daily oral dose of 300 mg as tegafur. Radiotherapy was delivered five days a week using a once-daily fractionation of 2.0 Gray (Gy), to a total dose of 66–72 Gy. The three-year overall survival rate with larynx preservation was 100 per cent. Concurrent chemoradiotherapy with carboplatin and UFT for stage two SCC of the glottic larynx was safe and effective in improving local control with larynx preservation.
Universe decay and changing the cosmological constant.

If superspace time is taken to be $\sqrt{\mathrm{det}(\ensuremath{\gamma})}$, where ${\ensuremath{\gamma}}_{\mathrm{ij}}$ is the three-metric, then the cosmological constant plays the role of a ${(\mathrm{mass})}^{2}$ term in the Wheeler-DeWitt equation. Second quantization allows particles of different mass to decay into one another if they are interacting. Likewise, adding interactions to the third-quantized Lagrangian allows universes with different cosmological constants to decay into one another. We consider a simple model with two types of universes, one of cosmological constant zero and the other nonzero. We compute the probability of decay and production for each type of universe.
Repeated Play and Newton's Method

Motivated by repeated play of non-cooperative games, we study equation solving undertaken in parallel by several non-communicating agents, each dealing with his own block of variables. The process is akin to Newton's method in using derivative information. It does, however, proceed without matrix inversion and dispenses with the need to exchange information between various blocks.
The relationships of classic psychedelic use with criminal behavior in the United States adult population

Criminal behavior exacts a large toll on society and is resistant to intervention. Some evidence suggests classic psychedelics may inhibit criminal behavior, but the extent of these effects has not been comprehensively explored. In this study, we tested the relationships of classic psychedelic use and psilocybin use per se with criminal behavior among over 480,000 United States adult respondents pooled from the last 13 available years of the National Survey on Drug Use and Health (2002 through 2014) while controlling for numerous covariates. Lifetime classic psychedelic use was associated with a reduced odds of past year larceny/theft (aOR = 0.73 (0.65–0.83)), past year assault (aOR = 0.88 (0.80–0.97)), past year arrest for a property crime (aOR = 0.78 (0.65–0.95)), and past year arrest for a violent crime (aOR = 0.82 (0.70–0.97)). In contrast, lifetime illicit use of other drugs was, by and large, associated with an increased odds of these outcomes. Lifetime classic psychedelic use, like lifetime illicit use of almost all other substances, was associated with an increased odds of past year drug distribution. Results were consistent with a protective effect of psilocybin for antisocial criminal behavior. These findings contribute to a compelling rationale for the initiation of clinical research with classic psychedelics, including psilocybin, in forensic settings.
Comparing disability survey questions in five countries: a study using ICF to guide comparisons

This paper describes an international effort to compare disability survey questions using the ICF framework. The process included backcoding survey questions to ICF. To establish a meaningful basis for comparison, the original 14 functioning areas were scaled to seven: hearing, seeing, speaking, mobility, body movement, gripping and personal care. The names of disability topics changed reflecting ICF definitions, for example, hearing became receiving spoken messages and gripping became fine hand use. A rigorous backcoding process resulted in a comprehensive set of survey questions with unique ICF codes. It was concluded that the question format and focus must be structured to the ICF in the survey development phase in order to achieve the best possible base for international comparability.
Reliability testing of in vivo 1H-MRS-signals and elimination of signal artifacts by median filtering

In order to make SV-MRS clinically viable, assessment of spectral quality and reliability of the data should preferably be handled by the MR-scanner system rather than by medical staff. The reliability of the data is most affected by patient motion during acquisition. In this paper, we devise, apply, and test two statistical methods that can be used for automated data reliability- and quality-assessment. Next, we establish that, in order to assess the reliability of SV-MR-data, it is essential to store the data of each acquisition separately, rather than averaging the data of all acquisitions irreversibly prior to storage. We propose a) statistical tests on these separately stored acquisitions that can reveal artifacts, b) application of a special type of order-statistics filtering, namely median filtering, once artifacts have been detected. Furthermore, we develop computer algorithms that provide automated, fully user-independent information on spectral quality and reliability of the acquired spectra. Finally, we conclude that combination of statistical tests with median filtering can provide user-free quality and reliability assessment and improvement of SV-MR-spectra.
Factors Affecting Motivation for Self-improvement in Academic Work Production of Private Universities’ Faculty Members

The purposes of this study were to assess the factors affecting motivation in the academic work production of private universities’ faculty members, and to develop the strategies which might better motivate Payap University’s faculty members to produce academic work. The primary sample consisted of 641 faculty members from private universities. Data collection was by means of interviewing and a 5 level rating scale questionnaire which was prepared with expert advice. Cornbach’s alpha coefficient for the questionnaire was . 949. The data was analysed by using Principle Component Extraction and Orthogonal Rotation with Varimax Method. The strategies were developed through a focus group from Payap University’s faculty. The result showed that there were 8 significant factors affecting motivation involving 64 parameters accounting for 66.724% of variances: an academic environment, pride in the achieved work, rewards and resulting contentment, support offered, institutional commitment, perception of duties, encouragement from peers and family, and quality assurance processes. The motivational strategies proposed for Payap University’s faculty members were tied to strategies proposed for improving academic environments, increasing pride in the achieved work, providing support facilities, rewarding members and gaining increased contentment, and institutional commitment. The proposed strategies were classified into 3 levels: institutional strategies, faculty level strategies and personal strategies.
Enhancing the ramp-up of a new contract logistics business by developing a workers requirements matrix

In contract logistics the ramp-up is very sensitive. This is due to the individual contracts, customized services, complex processes and especially those processes that are beyond transport, warehousing and handling – called Value Added Services. To fulfill those tasks, specific skills and qualifications, especially from workers, are required. On the one hand, if workers are under-qualified, the contractual agreements regarding level of service might not be reached. Then, penalties might get due. On the other hand, over-qualified workers might be more expensive than others and therefore, cause higher costs. To enhance the ability of contract logistics providers to select workers with the right qualifications and the right level of qualifications, an instrument for the structured analysis of necessary functions and qualifications of the human factor was developed. Thereby, the focus was on contract logistics in the automotive sector. The work will be described within this paper.
Tracking Power Photovoltaic System using Artificial Neural Network Control Strategy

Photovoltaic generation is the technique which uses photovoltaic cell to convert solar energy to electric energy. Nowadays, PV generation is developing increasingly fast as a renewable energy source. However, the disadvantage is that PV generation is intermittent because it depends considerably on weather conditions. This paper proposes an intelligent control method for the maximum power point tracking (MPPT) of a photovoltaic system under variable temperature and solar irradiation conditions. In this paper, a simulation study of the maximum power point tracking (MPPT) for a photovoltaic system using an artificial neural network is presented. The system simulation is elaborated by combining the models established of solar PV module and a DC/DC Boost converter. Finally performance comparison between artificial neural network controller and Perturb and Observe method has been carried out which has shown the effectiveness of artificial neural networks controller to draw much energy and fast response against change in working conditions.
Deletion of the Intestinal Peptide Transporter Affects Insulin and TOR Signaling in Caenorhabditis elegans*

The mammalian intestinal peptide transporter PEPT1 mediates the uptake of di- and tripeptides from the gut lumen into intestinal epithelial cells and acts in parallel with amino acid transporters. Here we address the importance of the PEPT1 orthologue PEP-2 for the assimilation of dietary protein and for overall protein nutrition in Caenorhabditis elegans. pep-2 is expressed specifically along the apical membrane of the intestinal cells, and in pep-2 deletion mutant animals, uptake of intact peptides from the gut lumen is abolished. The consequences are a severely retarded development, reduced progeny and body size, and increased stress tolerance. We show here that pep-2 cross-talks with both the C. elegans target of rapamycin (TOR) and the DAF-2/insulin-signaling pathways. The pep-2 mutant enhances the developmental and longevity phenotypes of daf-2, resulting, among other effects, in a pronounced increase in adult life span. Moreover, all aspects of a weak let-363/TOR RNA interference phenotype are intensified by pep-2 deletion, indicating that pep-2 function upstream of TOR-mediated nutrient sensing. Our findings provide evidence for a predominant role of the intestinal peptide transporter for the delivery of bulk quantities of amino acids for growth and development, which consequently affects signaling pathways that regulate metabolism and aging.
Nectins localize Willin to cell–cell junctions

Willin is a FERM‐domain protein, which is related to the Drosophila Expanded, a protein known to be a component of the Hippo signaling pathway. We recently showed that Willin localizes at the apical junctional complex (AJC) in epithelial cells together with Par3 and regulates the contractility of the circumferential actomyosin cables by recruiting aPKC to the AJC. However, it remains unresolved how Willin becomes associated with the AJC. Here, we report that Willin binds to nectins, Ig‐family proteins, which also localize at the AJC via their homophilic or heterophilic interactions, and this binding participates in the junctional recruitment of Willin. In addition, we report that the positioning of nectins at the AJC is dependent on their binding to afadin. Thus, our results suggest that the nectin–afadin interaction plays a role in the correct localization of Willin.
Good and laudable pus.

Editorial The ancient Greeks believed that suppuration of a wound was an expected feature of its natural history, and the physician encouraged the flow of what the Romans later called pus bonum et laudabile. This affirmative view of purulence held sway until the 19th century when Lord Lister refused to play the bacteria's game and strove to achieve clean, uninfected surgical wounds. Lister's theories of antisepsis changed the course of medical history with regard to wound sepsis; however, it subsequently became clear that additional modalities were needed to avert postoperative wound infection, especially when the intestinal flora with its rich source of microbes was the fount of contamination. In this issue Tzianabos et al. (1) extend the Listerian quest to prevent wound sepsis by attempting to fortify the host's immunological status. Surprisingly, their work has shown that protection against abscess caused by mixed aerobic-anaerobic flora is related to a T cell-dependent response which can be induced by immunization with a capsular polysaccharide complex from the major microbial component, Bacteroidesfragilis. This work is important since it suggests that immunization, either actively with this polysaccharide or passively with T cell-derived soluble mediators, might protect against infection by this organism as well as a mixed flora. Yet several questions remain unanswered. It is not clear that prevention of abscess, which is a complex structure requiring a collagen capsule, is necessarily related to prevention of wound infection, which is a complication five times more common than abscess after intraabdominal contamination. Does immunization with the capsular polysaccharide prevent wound infection with B. fragilis and its microbial running mates? Or is the protection related to the specific collagen-filled structure known as ab-scess? Another issue is the three rather different clinical settings of abscess formation for which polysaccharide immunization might be applied. The first condition is an established intraab-dominal abscess following sometime after peritonitis or a bowel injury. It seems unlikely that the approach of polysaccharide immunization would be effective here. Surgical intervention and antibiotics will probably be the deciding modalities in this situation. (An old definition of surgical intervention applies: "The swift and ready motion of steadfast hands with experience .") The second setting is elective bowel surgery which is frequently associated with inapparent bowel leakage and perito-neal soiling. In the modem era, using mechanical bowel preparation and effective antibiotic prophylaxis, the expected incidence of postoperative wound infection is-5-7% with an abscess rate of-1-2%. There would …
Why Is Multinational Status Important? Evidence from Job Creation and Job Destruction in Japan

Previous studies of job creation and job destruction (JCJD) have found that the gross job reallocation rate greatly exceeded the net job creation rate even in a narrowly defined industry or the same international trade orientation. This paper asks whether multinational enterprises (MNEs) reflect different patterns of JCJD compared to domestic firms. We distinguish two types of MNEs (i.e., Japanese MNEs and foreign-owned firms) and utilize firm-level data in Japan for 1995-2002. We find that the gross job reallocation rate may be equal to the net job creation rate once we control for the entry/exit, industry, worker type, and multinational status. Multinational status is important in explaining the heterogeneity of employment patterns among firms.
Balancing Strategies for an Unbalanced LiFePO4 Battery Pack

In this study, cases of lithium iron phosphate (LiFePO4) battery pack imbalance were categorized. The characteristics of each case were examined and identified on the basis of the imbalance categorization. Subsequently, balancing strategies for an unbalanced pack were proposed according to the characteristics of each case. To implement the balancing strategies, a bidirectional flyback converter was used for transferring the energy between a cell and a pack. Experimental results validate that an unbalanced pack can achieve a balanced state through the balancing strategies and a bidirectional flyback converter.
Langages Applicatifs et Machines Abstraites pour la Couverture de Code Structurelle. (Applicative Languages and Abstract Machines for Structural Code Coverage)

This thesis presents a study on structural code coverage fora language of the ML family, in response to an industrial need insafety-critical software domain to develop tools. In this context, MLappears as a particularly rich and high-level language with a highdegree of expressiveness. Its use is a progress but also raises issueswhen trying to apply classical safety-critical software engineeringprocesses. In particular, the two notions of condition and decision,as well as coverage criteria associated with them, rapidly become verycomplex. The first contribution of this thesis answers the question ofwhat conditions and decisions mean for a language of the ML family, bygiving several formal definitions. Then, we present a formalisedtechnique for structural code coverage which rewrites the source codeto produce traces at run-time. We name it the intrusiveinstrumentation. We also formalise another technique which does notrewrite the source code, which allows to use the same binary for bothtesting activities and production. This second technique is called nonintrusive and consists in generating at compile-time the informationneeded to match the machine code back to the source code. Otherinformation are also generated for the execution environment to recordspecific traces that we need to generate a coverage report involvingBoolean measures. Finally, we compare these two techniques bothformally and practically, but also in terms of implementation.
Entrepreneurial Entry, Exit and Re-Entry: The Extent and Nature of Opportunity Identification

This study utilizes a human capital framework to explore whether business ownership experience is associated with the number of business opportunities identified, the number of identified opportunities that are pursued, and the nature of those opportunities. Information from a large representative sample of owners of 631 private independent firms is utilized. Controlling for various dimensions of entrepreneurs' general and specific human capital, we find that experienced (habitual) entrepreneurs identify more business opportunities, pursue more of these opportunities and are associated with more innovative opportunities. We can infer that business ownership experience acts as an important guide for entrepreneurs in processing information in a manner than allows them not only identify more opportunities but potentially more innovative ones too.
Multidimensional auctions for long-term procurement contracts under the threat of early exit

In this paper we study how early-exit options, embedded in long-term procurement contracts which do not provide for sufficiently strong incentives against contract breach, can affect bidding behaviors in multidimensional procurement auctions and the parties' expected payoffs. We show first that bidders' payoff is lower when competing for contracts with unenforceable contract terms. Secondly, that neglecting the risk of opportunistic behavior by sellers can lead to contract awards that do not maximize the buyer's potential payoff. Finally, we make suggestions about how to mitigate potential misallocations, by pointing out the role of eligibility rules and competition among bidders.