Miracle-dz/UniFAR-FTUs huggingface dataset:
An efficient list scheduling algorithm with task duplication for scientific big data workflow in heterogeneous computing environments

A high‐performance heterogeneous computing environment provides computing resources for efficient computation of scientific Big Data workflow applications. A Big Data workflow application comprises thousands of interdependent tasks with precedence constraints. Basically, the performance of heterogeneous computing systems mainly depends on the workflow scheduling algorithms. These workflow scheduling algorithms are considered an NP‐complete problem. In this article, a List Scheduling with Task Duplication (LSTD) algorithm is proposed that efficiently minimizes the makespan of workflow applications. The LSTD introduces task duplication strategy in the list scheduling algorithm without increasing the overall time complexity. The overall functionality of LSTD mainly consists of three phases. In the first phase, it calculates the rank of the tasks for deciding the scheduling order. The next step is responsible for duplicating the entry task on the processor only if it increases the overall efficiency and avoids processor overloading. Finally, in the last step, the processor is assigned to the tasks based on the popular insertion‐based policy that attempts to insert the task among two earlier assigned tasks on a given processor in earliest idle time. In order to verify the usefulness of the proposed algorithm, several existing well‐known algorithms, such as Heterogeneous Earliest Finish Time (HEFT), Critical Path on a Processor (CPOP), and Predict Earliest Finish Time (PEFT) are considered for comparison. A non‐duplication version of LSTD named List Scheduling without Task Duplication algorithm is also considered for performance evaluation. The experimental analysis based on scientific Big Data workflows (CyberShake, Montage, and LIGO) proves that LSTD significantly surpasses all considered scheduling heuristics concerning schedule length ratio, the percentage of best results, and average running time metrics.
Aristotle as an ichthyologist: Exploring Aegean fish diversity 2,400 years ago

In an attempt to trace the origins of the science of ichthyology, we studied Aristotle's zoological works (21 books in total), aiming to give an exhaustive catalogue of his fishes, suitable for use by modern marine biologists, and to evaluate the great philosopher's knowledge of fish biology. Our investigation yielded 135 ichthyonyms used to describe 109 individual fish taxa (13 fishes had multiple names) and 12 terms that corresponded either to fish developmental stages or behavioural patterns. Because of the variable amount of information given in the texts, 54 fishes were identified to species or genus level, 24 fishes to higher categories (family, order), 27 fishes could only be classified as Actinopterygii or Elasmobranchii, while four could not be classified at all. Among the most easily recognizable fishes were Lophius spp. , Conger conger, Muraena helena, Anguilla anguilla and Mugil cephalus. The latter two and the tunas (Τhunnus spp.) were the most frequently recorded fishes. Aristotle's inquiry was not limited or focused on fish that were of human interest, but he also reported or described species that fascinated him by their peculiar life history. He was interested in a wide array of aspects of fish biology ranging from body structure and function, reproduction and development to fish feeding habits, migrations and diseases. As evidenced by his work, Aristotle should be considered the first ichthyologist, preoccupied with the zoological, scientific study of fish, and a review of his writings can prove useful for current ichthyological research.
Service Learning as Inquiry in an Undergraduate Science Course

Abstract To engage students in applying scientific process skills to real-world issues, we implemented a service-learning project model in our undergraduate introductory biology course for science majors. This model illustrates how we integrate inquiry inside and outside of the classroom through four steps: service, learning, classroom, and community. Out-of-class activities engaged students in serving the community (Service step) while deepening their learning experience beyond what they would learn in a classroom (Learning step). To connect the service-learning project with scientific process skills, students were asked to identify problems that our community partners were trying to solve, identify proposed solutions, and design ways to evaluate those solutions (Classroom step). Additionally, students connected their service-learning topic with core concepts in Biology. After their service, students used metrics to analyze their impact. Students then synthesized the connection between their service, learning, and classroom projects by presenting their findings to the scientific and lay communities through a poster session (Community step). Here we provide details of the model, recommendations, and examples for others to execute an inquiry-based service-learning project.
Enhanced Adsorptive Removal of β-Estradiol from Aqueous and Wastewater Samples by Magnetic Nano-Akaganeite: Adsorption Isotherms, Kinetics, and Mechanism

A surfactant-free method was used to synthesize iron oxyhydroxide (akaganeite, β-FeOOH) nanorods and characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy combined with energy-dispersive X-ray spectroscopy (SEM-EDS), and transmission electron microscopy (TEM). The synthesized nanoadsorbent was applied for the adsorptive removal of β-estradiol from aqueous solutions. The parameters affecting the adsorption were optimized using a multivariate approach based on the Box–Behnken design with the desirability function. Under the optimum conditions, the equilibrium data were investigated using two and three parameter isotherms, such as the Langmuir, Freundlich, Dubinin–Radushkevich, Redlich–Peterson, and Sips models. The adsorption data were described as Langmuir and Sips isotherm models and the maximum adsorption capacities in Langmuir and Sips of the β-FeOOH nanorods were 97.0 and 103 mg g−1, respectively. The adjusted non-linear adsorption capacities were 102 and 104 mg g−1 for Langmuir and Sips, respectively. The kinetics data were analyzed by five different kinetic models, such as the pseudo-first order, pseudo-second order, intraparticle, as well as Boyd and Elovich models. The method was applied for the removal β-estradiol in spiked recoveries of wastewater, river, and tap water samples, and the removal efficiency ranged from 93–100%. The adsorbent could be reused up to six times after regeneration with acetonitrile without an obvious loss in the removal efficiency (%RE = 95.4 ± 1.9%). Based on the results obtained, it was concluded that the β-FeOOH nanorods proved to be suitable for the efficient removal of β-estradiol from environmental matrices.
Perivascular stem cells at the crossroads of tissue regeneration and pathology

ii Acknowledgements . iv Table of Figures and Tables . xiv List of abbreviations . xx General Introduction . 1 Adult stem cells: position among other stem cells in terms of biologic and therapeutic potentials . 2 Mesenchymal stem cells (MSC) . 3 Definitions and in vitro behaviours of MSC . 5 Nomenclature . 7 Are MSC true stem cells? 8 The immunophenotype of MSC . 8 MSC isolated from different organs exhibit unique features. 12 Anatomical location of MSC . 12 Perivascular stem cells (PSC) . 14 Nonpericyte perivascular cells as MSC ancestors . 16 A Perivascular Niche for MSC precursors. 17 PSC as regenerative units . 19 Pericytes can contribute to skeletal myoblasts and satellite cells, and odontoblasts. 20 PSC as regenerative units in cell therapy . 21 Table of
SET-VALUED PERFORMANCE APPROXIMATIONS FOR THE $GI/GI/K$ QUEUE GIVEN PARTIAL INFORMATION

In order to understand queueing performance given only partial information about the model, we propose determining intervals of likely values of performance measures given that limited information. We illustrate this approach for the mean steady-state waiting time in the $GI/GI/K$ queue. We start by specifying the first two moments of the interarrival-time and service-time distributions, and then consider additional information about these underlying distributions, in particular, a third moment and a Laplace transform value. As a theoretical basis, we apply extremal models yielding tight upper and lower bounds on the asymptotic decay rate of the steady-state waiting-time tail probability. We illustrate by constructing the theoretically justified intervals of values for the decay rate and the associated heuristically determined interval of values for the mean waiting times. Without extra information, the extremal models involve two-point distributions, which yield a wide range for the mean. Adding constraints on the third moment and a transform value produces three-point extremal distributions, which significantly reduce the range, producing practical levels of accuracy.
Thomas Woodrow Wilson’s Contributions to Administrative Though and Its Critique

The intellectual root of public administration as a distinct field of study can be traced to the pioneering contributions made by Thomas Woodrow Wilson in the 1880s. It started with the publication of Wilson's “The Study of Administration in 1887 in the Political Science Quarterly. Wilson’s famous essay and the discussion it generated were of unparallel importance to the development of public administration as a distinct field of study. In spite of its popularity and wide acceptance, Wilson's idea has a number of serious limitations for which it has been criticized by a number of Scholars. Prominent among these scholars were Max Weber, Susan Barrett and Colin Fudge. After careful analysis, we confidently concluded that the development of public administration as a distinct discipline of study was Wilson’s ideas. The objective of this paper therefore was to carefully analyzed Wilson’s contribution to administrative thought and its criticisms.
Pairwise mutual knowledge and correlated rationalizability

We provide epistemic conditions for correlated rationalizability, which are considerably weakerthan the ones by Zambrano (2008). More specifically, we simultaneously replace mutual knowledge ofrationality and mutual knowledge of the event that every player deems possible only strategyprofiles that belong to the support of her actual conjecture, with strictly weaker epistemicconditions of pairwise mutual knowledge of these events.Moreover, we show that our epistemic foundation for correlated rationalizability does not implymutual knowledge of rationality.
Broad‐scale variation in sexual dichromatism in songbirds is not explained by sex differences in exposure to predators during incubation

: The evolution of sexual dichromatism provoked one of the greatest disagreements between Charles Darwin and Alfred Russel Wallace. According to Darwin the main driving force is sexual selection, whereby choosy females prefer showy males, leading to the evolution of conspicuous male plumage. On the other hand, Wallace suggested that dichromatism may arise because nest predation favors more cryptic females. To test the role of natural selection in the evolution of dichromatism we combined quantitative data on differences in parental share in nest attentiveness (representing the strength of natural selection on males vs. females) with spectrophotometric measurements of dichromatism in 412 species of songbirds from 69 families. We expected to find stronger dichromatism in open-nesting species with more divergent parental roles and in body parts exposed during incubation. Dichromatism was not related to the differences in parental share during incubation, but it was most pronounced in lekking species, migrants, and small species. Our results thus suggest that Wallace's hypothesis is not able to explain broad-scale variation in the dichromatism of songbirds, but point to a role for sexual selection, mutual mate choice, and migration strategy in shaping the extraordinary variation in dichromatism exhibited by songbirds. This article is protected by copyright. All rights reserved.
Improving the Operational Efficiency of Parcel Delivery Network with a Bi-Level Decision Making Model

This article proposes a mathematical model for integrating terminal operation strategies with shipment scheduling. We are motivated by findings from the literature on the integrated design of logistic systems. The objective of this research is to efficiently utilize the existing hub terminals and transport network by considering the minimization of costs related to terminal congestion, transport, and carbon dioxide (CO2) emissions. Cooperative behaviors of terminal managers and fleet assignment managers are modeled in a bi-level problem framework. The total cost includes a processing cost and transport cost, and CO2 related to the assigned fleets. We introduce a terminal cost function to capture the relationship between unit processing cost with respect to hub delay, which allows us to find the minimum cost path and efficiently distribute shipments to hub terminals. The case study shows that the collaborative logistics outperforms a single routing strategy and capacity expansions in minimization of both total cost and CO2 emissions.
Anti-Cancer Strategies of Methylglyoxal A Review

Methylglyoxal a simple carbonyl compound containing a reactive aldehyde and a ketonic group which stops the growth of cancer cells without poisoning normal cells. It is also called as Retine. These are very small molecules that are highly potent in controlling cell division. This compound inhibits the enzymes required for cancer cell and infected cell to grow by respiration and does not harm normal cells. As cancer cells require large amount of energy to multiply which was provided by ATP. Methylglyoxal inactivates the enzyme Glyceraldehyde-3-phosphate Dehydrogenase (GA3PD) needed for the ATP production in cancer cells and there by starves the cell to death and normal cells remain unaffected. As it is a carbonyl group, it inhibits the mitochondrial respiration followed by Glycolysis and Kreb’s cycle which play a major role in the production of ATP and supplies the energy to infected cell up to demand. It also play a role in binding of oxygen at cellular level and preventing the proteins to desaturate and inhibits the production of free radicals. Hence suitable energy and oxygen are unavailable to cancerous cell to grow, leading to death of the cell. It was believed that “If cancer cell cannot grow, it dies by itself”. It desaturate the proteins of malignant cell at cellular level by means of its ketoaldehyde group with an aminoacid of a protein causing the death of cell.
How innovation intermediaries support start-up internationalization: a relational proximity perspective

Purpose: This paper examines how innovation intermediary activities increase relational proximity between start-ups and foreign partners to support internationalization Methodology: The paper applies a case study methodology to examine an international network of innovation intermediaries in the resources sector. Interviews were conducted with fifty-nine start-up, corporate and intermediary managers in four countries, supplemented by secondary data. A two-stage analysis process was performed to first identify activities relating to start-up internationalization and then apply a theoretically derived coding framework based on five proximity dimensions. Findings: The case identifies several innovation intermediary activities, which facilitate relationship development between start-ups and partners in new markets. Findings outline how activities increase relational proximity across different dimensions, while also indicating a number of interrelations between dimensions. Originality/value: This paper establishes interdisciplinary bridges between business network, international business and economic geography perspectives. It provides a valuable empirical foundation for relational proximity, demonstrating its application to understanding start-up internationalization and its influence by intermediary-led activities.
Home Activity-based Interventions for the Neurologically Impaired Upper Extremity: A Scoping Review

Background: Activity-based therapy (ABT) for the upper extremity (UE) enables neurologic recovery with tasks that are functional, intense, and highly repetitive. A large proportion of rehabilitation occurs in the home and there is a gap in literature on the application of ABT within the home. The objective of this scoping review was to describe ABT in the home-setting for the neurologically-impaired UE. Methods: A systematic scoping review included searches of: MEDLINE, CINAHL, Cochrane, and OTSeeker. Results: A systematic search yielded 51 final studies. About 61% of ABT studies were exclusively within the home, others included outpatient visits (37%). Telerehabilitation was used in 37% of the studies with live-video and store forward techniques equally represented. ABT supported by technology was used in 61% of studies. Dosing of intervention ranged from 7 to 120 hours, with a mean of 34.5 hours of practice. Adherence with intended dosing was reported in 27% of studies and subjects completed a mean of 86% of the intended practice time. Sixty-seven percent of studies reported some degree of practice without therapist supervision. Conclusions: The results showed wide variability in the intervention methods, dosing and technology used in homebased settings. The high rate of adherence with dosing is encouraging for the application of homebased neurologic UE interventions. This scoping review highlights feasibility of UE ABT within the home and need for further research.
A simulation-based analysis of photovoltaic thermal hybrid solar collectors with a new TRNSYS type model

Nowadays buildings are responsible of 36% of CO2 emissions and space heating and cooling alone accounts for 40% of the final energy consumption at European level. In this context, solar-assisted systems represent an important solution to support the decarbonisation pathways in residential sector. In this work, a novel lumped parameter simulation model for photovoltaic thermal hybrid solar collectors developed by Authors as a type of Transient System Simulation (TRNSYS) software is used to carry out computer simulations in different climatic conditions. The model is based on the electrical analogy method to solve the transient heat transfer problem and considers the effect of the thermal capacitances of the elements composing the photovoltaic thermal collector. The simulation tool was also validated with the experimental data in terms of both electrical and thermal power. In this work, a simulation-based analysis is carried out considering three climatic zones in order to evaluate the thermal performance of photovoltaic thermal hybrid solar collectors under different operating conditions.
Primary Myxoid Liposarcoma of the Lower Back in an Adult Female Patient: An Extremely Rare Presentation

Myxoid liposarcoma is the second most common type of liposarcoma that typically presents in the lower extremities and has a predilection for men. Manifestation of this tumor in the lower back is rare. We report the first known case of an adult woman presenting with a soft tissue mass in her lower back. Following excision and further workup, the mass was positive for rearrangements of the DDIT3 (CHOP) gene at the 12q13 locus, consistent with the diagnosis of a myxoid liposarcoma. The tumor was noted to be intramuscular and extended into the margins, requiring re-excision at the previous resection site. Biopsy of the re-excised area was negative for evidence of residual myxoid liposarcoma. We report this case to highlight the importance of considering myxoid liposarcoma as a differential diagnosis in soft tissue masses presenting in the lower back.
Silver nanoparticles biosynthesis by Fusarium moniliforme and their antimicrobial activity against some food-borne bacteria

The biosynthesis of metal nanoparticles is an expanding research area due to the potential applications for emerging ecofriendly science. The present study proved a rapid and extracellular biosynthesis of silver nanoparticles ( AgNPs) by a fungus, Fusarium moniliforme , isolated from infected onion. Upon addition of the silver ion into the flask containing the mycelial mat, the color of the medium changed to brown, typical of the AgNPs . The AgNPs showed maximum absorbance at 420 nm on ultraviolet-visible spectra. The transmission electron micrograph revealed the formation of AgNPs with an average size of about 50-100 nm. The presence of proteins was identified by Fourier transform-infrared spectroscopy. Combination between AgNPs and ciprofloxacin was evaluated for their antimicrobial activities, and the antibacterial activity of ciprofloxacin was increased in the presence of AgNPs against some food borne bacteria i.e. Bacillus subtilis , Staphylococcus aureus , Escherichia coli and Salmonella typhi .
Regulation of the Rat Hepatic NADPH-cytochrome P450 Oxidoreductase by Glucocorticoids

ii ACKNOWLEDGEMENTS.iii TABLE OF CONTENTS.v LIST OF TABLES.vii LIST OF FIGURES.viii LIST OF ABBREVIATIONS.xi LIST OF ABSTRACTS.xiv SECTION 1: INTRODUCTION.1 1.1 STATEMENT OF RESEARCH PROBLEM.1 1.2 HYPOTHALAMIC-PITUITARY-ADRENAL AXIS.2 1.3 GLUCOCORTICOIDS.7 1.3.1 Synthetic Glucocorticoids.9 1.3.2 Cushing’s Syndrome.12 1.3.3 Addison’s Disease.13 1.4 NUCLEAR RECEPTORS.14 1.4.1 Glucocorticoid Receptor.17 1.4.2 Pregnane X Receptor.23 1.4.3 GR-PXR Crosstalk.27 1.5 CYTOCHROME P450 ENZYMES.30 1.5. 1 NADPH-cytochrome P450 oxidoreductase.33 1.6 RESEARCH HYPOTHESIS.38 1.7 SPECIFIC OBJECTIVES.39 1.8 RATIONALE FOR THE EXPERIMENTAL APPROACH.40 SECTION 2: MATERIALS AND METHODS.43 2.1 ANIMALS AND TREATMENT PROTOCOLS.43 2.2 RNA ISOLATION.45 2.3 RNA INTEGRITY.46 2.4 REVERSE TRANSCRIPTION.46 2.5 CONVENTIONAL RT-PCR.48 2.6 QUANTITATIVE REAL-TIME PCR.50 2.7 MICROSOMAL FRACTIONATION.50 2.8 LOWRY PROTEIN ASSAY.53 2.9 IMMUNOBLOTTING.54 vi 2.10 CYTOCHROME C REDUCTION AS A MEASURE OF POR ACTIVITY.58 2.11 STATISTICAL ANALYSIS.58 SECTION 3: RESULTS.61 3.1 DEX DOSE-RESPONSE.61 3.1.1 DEX dose-response: POR, TAT, CYP3A23 and PXR mRNA.61 3.1.2 DEX dose-response: POR protein.64 3.1.3 DEX dose-response: POR activity.64 3.2 GRAND PXR-SELECTIVE AGONISTS.67 3.2.1 GRand PXR-selective agonists: POR, TAT, CYP3A23 and PXR mRNA.67 3.2.2 GRand PXR-selective agonists: POR protein.71 3.2.3 GRand PXR-selective agonists: POR activity.71 3.3 GR ANTAGONISM.71 3.3.1 GR antagonism: POR, TAT, CYP3A23 and PXR mRNA.75 3.3.2 GR antagonism: POR protein.75 3.3.3 GR antagonism: POR activity.80 3.4 PXR-KO.80 3.4.1 PXR-KO: POR, TAT, CYP3A23 and PXR mRNA.80 3.4.2 PXR-KO: POR protein.84 3.4.3 PXR-KO: POR activity.84 SECTION 4: DISCUSSION.88 4.1 SUMMARY OF MAIN FINDINGS.88 4.1.1 DEX dose-response.88 4.1.2 GRand PXR-selective agonists.89 4.1.3 GR antagonism.90 4.1.4 PXR-KO.91 4.2 MOLECULAR MECHANISMS OF POR REGULATION.92 4.2.1 Transcriptional regulation of POR expression: a potential role for GR.93 4.2.2 Transcriptional regulation of POR expression: a potential role for PXR.95 4.2.3 Post-transcriptional regulation of POR expression.96 4.2.4 Translational and post-translational regulation of POR expression.98 4.2.5 GR-PXR crosstalk.99 4.3 PHYSIOLOGICAL AND PHARMACOLOGICAL RELEVANCE.101 4.4 LIMITATIONS OF THE CURRENT STUDY.103 4.4.1 Doses of DEX and limited time points.103 4.4.2 GR antagonism with RU486.104 4.4.3 Rat strains.105 4.5 FUTURE RESEARCH DIRECTIONS.106 4.6 SUMMARY AND SIGNIFICANCE.109 SECTION 5: REFERENCES.111
Evaluation of the performance of bacillus cereus and bacillus subtilis as Test organisms for assay of tetracyclines and beta-lactams in Chicken meat

vi TABLE OF CONTENTS . vii LIST OF ABBREVIATIONS . ix LIST OF TABLES . x LIST OF FIGURES . xi LIST OF PLATES . xii APPENDICES . xiii CHAPTER ONE .