Miracle-dz/UniFAR-FTUs huggingface dataset:
A novel Mobius-coupled printed resonator based signal sources

A novel Mobius-coupled printed resonator oscillators is developed in response to replacing expensive DRO (Dielectric Resonator Oscillator) for the application of synthesized signal sources in RADAR and modern microwave communication systems. One of the problems related to the Dielectric Resonator (DR) is miniaturization at lower microwave frequencies and also fabrication in integrated circuit (IC) form due to 3-Dimensional structure. Shrinking the size of planar resonators employing Mobius coupling mechanism has led to tiny (0.3 × 0.3 inches) broadband (2-8 GHz) tunable oscillators for inexpensive low phase noise signal source applications. For the validation, 2-8 GHz synthesizer was built, exhibit phase noise - 120dBc/Hz at 10 kHz offset from the carrier, settling time ~ 1 millisecond operating DC bias : 5V and 200 mA.
Effects of injection rates of contrast material on arterial phase hepatic CT.

OBJECTIVE Our goal was to assess the effects of the i.v. injection rate of contrast material on arterial phase hepatic CT. SUBJECTS AND METHODS One hundred patients were randomly divided into four groups of 25 with different injection rates of 90 ml of contrast material: 2, 3, 4, or 5 ml/sec. Single-level serial CT was performed at the level of the middle section of the main portal vein before injection and every 2 sec from 12 sec to 60 sec after injection of contrast material. The enhancement value was calculated as the difference in attenuation value between the unenhanced and contrast-enhanced images for the aorta and liver parenchyma. The duration of the arterial phase was defined as the interval beginning when the enhancement value for the aorta reached 100 H and ending when the value for the liver parenchyma reached 20 H. RESULTS Faster injection rates increased the maximum enhancement of the aorta. Although faster injection rates decreased the time from injection to the beginning and the end of the arterial phase, faster injection rates did not decrease the duration of the arterial phase itself. CONCLUSION A faster injection rate increases arterial enhancement of the liver, and the duration of the arterial phase remains the same as that occurring with a slower injection rate. We hypothesize that faster injection rates can provide better results using CT to reveal hypervascular liver tumors.
Dipsticks for rapid detection of Plasmodium in vectoring Anopheles mosquitoes

Abstract. Malaria remains the most serious vector‐borne disease, affecting some 300–500 million people annually, transmitted by many species of Anopheles mosquitoes (Diptera: Culicidae). Monoclonal antibodies developed against specific circumsporozoite (CS) proteins of the main malaria parasites Plasmodium falciparum and P. vivax have been used previously for enzyme‐linked immunosorbent assays (ELISA), widely employed for detection of malaria sporozoites in vector Anopheles for local risk assessment, epidemiological studies and targeting vector control. However, ELISA procedures are relatively slow and impractical for field use. To circumvent this, we developed rapid wicking assays that identify the presence or absence of specific peptide epitopes of CS protein of the most important P. falciparum and two strains (variants 210 and 247) of the more widespread P. vivax. The resulting assay is a rapid, one‐step procedure using a ‘dipstick’ wicking test strip. In laboratory assessment, dipsticks identified 1 ng/mL of any of these three CS protein antigens, with sensitivity nearly equal to the CS standard ELISA. We have developed and are evaluating a combined panel assay that will be both qualitative and quantitative. This quick and easy dipstick test (VecTest™ Malaria) offers practical advantages for field workers needing to make rapid surveys of malaria vectors.
Ventricular Assist Devices in Patients with Systemic Right Ventricular Failure due to Congenitally Corrected Transposition of the Great Arteries

Congenitally corrected transposition of the great arteries is increasingly recognized as an adult congenital heart problem. Although early atrial switch surgical repairs resulted in improved overall survival, these patients are further predisposed to systemic ventricular failure in their fourth and fifth decades of life. Early diagnosis and management of systemic ventricular dysfunction are often challenging. Ventricular assist devices may become a mainstay endstage treatment option for these patients as a destination therapy or a bridge to heart transplantation.
Prevalence of human papillomavirus types in women screened by cytology in Germany

Incidence and mortality rates of cervical cancer are higher in Germany than in other Western European countries. Type‐specific human papillomavirus (HPV) distribution was investigated for the first time in Germany in an epidemiological study including 8,101 women. Women above the age of 30 years, self‐referring for cervical cancer screening, were enrolled in two study centers in Hannover (Northern Germany) and Tübingen (Southern Germany). Participants were screened by the Pap smear and the hybrid capture 2 (HC2) test using the high‐risk probe. All samples that were positive by the HC2 test were genotyped using the prototype PGMY09/11 PCR line blot assay. Most women in the study population had a negative Pap smear (96.7%). Prevalence of high‐risk type HPV detected by HC2 was 6.4% and prevalence of carcinogenic types detected by PGMY09/11 was 4.3%. Of the PGMY09/11 PCR‐positive women, 70.2% had a single infection, 28.1% had multiple infections and 1.7% remained uncharacterized. 32 different HPV types were detected using PGMY09/11 PCR. HPV 16, 31, 52, 51, 18, and 45 were the most common carcinogenic types in the study population. Among women with histologically confirmed high‐grade lesions HPV 16, 45, 58, 18, 31, 33, and 52 were the predominant types. These results provide valuable information for the management of HPV infections in Germany, both in terms of future strategies of screening and vaccination. J. Med. Virol. 79:616–625, 2007. © 2007 Wiley‐Liss, Inc.
p57Kip2 Regulates Actin Dynamics by Binding and Translocating LIM-kinase 1 to the Nucleus*

p57Kip2 is the only cyclin-dependent kinase (Cdk) inhibitor shown to be essential for mouse embryogenesis. The fact suggests that p57 has a specific role that cannot be compensated by other Cdk inhibitors. LIM-kinase 1 (LIMK-1) is a downstream effector of the Rho family of GTPases that phosphorylates and inactivates an actin depolymerization factor, cofilin, to induce the formation of actin fiber. Here we demonstrate that p57 regulates actin dynamics by binding and translocating LIMK-1 from the cytoplasm into the nucleus, which in turn results in a reorganization of actin fiber. The central region of p57, a unique feature among the Cdk inhibitors, and the N-terminal region of LIMK-1, which contains the LIM domains were essential for the interaction. Expression of p57, but not p27Kip1 or a p57 mutant, with a deletion in the central region was shown to induce marked reorganization of actin filament and a translocation of LIMK-1. Our findings indicate p57 may act as a key regulator in embryogenesis by bearing two distinct functions, the regulation of cell cycle through binding to Cdks and the regulation of actin dynamics through binding to LIMK-1, both of which should be important in developmental procedure.
An Application of Apriori Algorithm in SEER Breast Cancer Data

In this work, we adopt Apriori Algorithm to explore the relationship between treatment preferences and survival of breast cancer patient based on other medical attributes. The SEER Public-Use Data 2005 is used in this research. After the preprocessing of the dataset, we apply Apriori algorithm of Association Rules. As a result, we obtain a great deal of association rules related. We pick up some easy understandable and comparable rules to discuss and show that data mining technique is a efficient method to explore the relationship between breast cancer treatment preferences and survivability. Medical experts could continue our research and found more meaningful knowledge.
Nonlinearity Control of Nanoelectromechanical Resonators

To achieve high performance of nanoelectromechanical resonators in room-temperature and low-vacuum conditions, the precise control of electrothermal power is critical in not only frequency tuning but also regulating nonlinearity in the radio-frequency range. This study presents theoretical analysis and experimental results for controlling nonlinearity of nanoelectromechanical resonators using nonlinear damping and stiffness terms. Experiments show that, with increasing electrothermal power, critical amplitude increases up to where the resonators display linear harmonic oscillation. As a result, the linearity of the resonator that has been driven into the nonlinear regime can be reclaimed.
A Modeling of Multilevel DRM

The widespread use of the Internet raises issues regarding intellectual property. After content is downloaded, no further protection is provided on that content. DRM (Digital Rights Management) technologies were developed to ensure secure management of digital processes and information. In this paper, we present a multilevel content distribution model of which we present formal descriptions.
Knowledge Sharing Between Individuals

As Peter Drucker (2000) has pointed out, the foundation of the 21st century organization is no longer money or capital or even technology; it is knowledge. In order for that knowledge to create value, it must be shared. Some discussions of knowledge sharing in organizations and, indeed, some knowledge management initiatives seem to assume that given the right technology and/or the proper culture, knowledge will flow readily throughout the firm. Technologies that facilitate knowledge sharing (e.g., databases, intranets, and groupware) currently exist and are constantly improving. But technologies are only part of the knowledge management equation. In 1997, the Ernst and Young Center for Business Innovation conducted a study of 431 U.S. and European organizations (Ruggles, 1998). Of those responding, only 13% rated their organizations as good or excellent at sharing knowledge internally. Even when knowledge was accessible, only 30% reported that their organizations were good or excellent at using that knowledge in making decisions. When asked what was the biggest obstacle to knowledge sharing within their organizations, 54% cited culture. To understand knowledge sharing within an organization, we must look beyond culture and start with the individual.
Variable Importance using Decision Trees, Supplementary Material for NIPS 2017 paper

We present a complete presentation of the theoretical results presented in the main text. We provide detailed analysis of the DStump algorithm in the context of a general additive regression model with uncorrelated design. We derive the results for the linear case as special case of the general theory. Our analysis is high-dimensional and non-asymptotic, and to our knowledge the ﬁrst such analysis of feature selection properties of decision trees. We show that even in the high-dimensional setting where the number of features p is much larger that the sample size n , feature importance scores based on impurity reduction contain enough information for consistent model selection. Additionally, we provide simulation experiments to supplement the results in the main text
Overexpression of Galgt 2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice

Paul T. Martin, Rui Xu, Louise R. Rodino-Klapac, Elaine Oglesbay, Marybeth Camboni, Chrystal L. Montgomery, Kim Shontz, Louis G. Chicoine, K. Reed Clark, Zarife Sahenk, Jerry R. Mendell, and Paul M. L. Janssen Center for Gene Therapy, The Research Institute at Nationwide Children’s Hospital, Department of Pediatrics; and Department of Physiology and Cell Biology, The Ohio State University College of Medicine, Columbus, Ohio
Cold denaturation of proteins.

This article summarizes all experimental facts concerning the cold denaturation of single-domain, multi-domain, and multimeric globular proteins in aqueous solutions with and without urea and guanidine hydrochloride. The facts obtained by various experimental techniques are analyzed thermodynamically and it is shown that the cold denaturation is a general phenomenon caused by the very specific and strongly temperature-dependent interaction of protein nonpolar groups with water. Hydration of these groups, in contrast to expectations, is favorable thermodynamically, i.e., the Gibbs energy of hydration is negative and increases in magnitude at a temperature decrease. As a result, the polypeptide chain, tightly packed in a compact native structure, unfolds at a sufficiently low temperature, exposing internal nonpolar groups to water. The reevaluation of the hydration effect on the base of direct calorimetric studies of protein denaturation and of transfer of non-polar compounds into water leads to revision of the conventional conception on the mechanism of hydrophobic interaction. The last appears to be a complex effect in which the positive contributor is van der Waals interactions between the nonpolar groups and not the hydration of these groups as it was usually supposed.
Mechanism of hepatoprotection in proestrus female rats following trauma‐hemorrhage: heme oxygenase‐1‐derived normalization of hepatic inflammatory responses

Hepatic damage occurs in males and ovariectomized (OVX), not in proestrus (PE), females following trauma‐hemorrhage (T‐H). The mechanism responsible for hepatoprotection remains unknown. We hypothesized protection in PE is a result of enhanced heme oxygenase‐1 (HO‐1)‐derived down‐regulation of liver inflammatory responses. PE and OVX rats underwent T‐H (midline laparotomy, 60% blood loss). PE rats received vehicle (Veh; saline), HO‐1 inhibitor chromium mesoporphyrin IX chloride (CrMP; 2.5 mg/kg), zinc protoporphyrin IX (ZnPP; 25 mg/kg), or Akt/PI‐3K inhibitor Wortmannin (Wort; 1 mg/kg) 30 min prior to resuscitation or sham operation i.p. OVX rats received Veh or 17β‐estradiol (E2; 1 mg/kg) 30 min before hemorrhage. Rats were killed 2 h thereafter. Following T‐H, left ventricular performance was maintained in PE and E2 OVX rats but was depressed in OVX and CrMP‐, ZnPP‐, and Wort‐treated PE rats; liver damage was not evident in PE rats, and CrMP, ZnPP, and Wort abrogated protection; liver HO‐1, p38 MAPK, Akt/PI3K, and Bcl‐2 expression increased in PE and E2 OVX rats, which was abrogated by CrMP, ZnPP, and Wort, and liver ICAM‐1, caspase‐3, phospho‐IκB‐α, and NF‐κB expression increased in OVX and CrMP‐, ZnPP‐, and Wort‐PE rats; liver myeloperoxidase, NF‐κB DNA‐binding activity, TNF‐α, IL‐6, plasma proinflammatory cytokines, and cytokine‐induced neutrophil chemoattractants increased in OVX and CrMP‐, ZnPP‐, and Wort‐PE rats; and plasma estradiol levels and hepatic estrogen receptor‐α and ‐β expression decreased in OVX but were unaltered by CrMP, ZnPP, and Wort. Thus, enhanced HO‐1 in PE and E2 OVX females modulates inflammatory responses and protects liver following T‐H.
The CoreMedia Process for Content Applications

Zusammenfassung Die CoreMedia AG hat aus den Erfahrungen mehrerer Projekte mit dem Content Management System „CoreMedia Publisher“ einen Software Engineering Prozess für die Anforderungen von Internet-Projekten gewonnen. Der CoreMedia Prozess adressiert mehrere Aspekte: den Umgang mit unklaren fachlichen Anforderungen, kurze Realisierungszeiträume, hohe Last und die Integration mehrerer Standardprodukte. Die Verwendung von Architekturmustern ist ein hilfreiches Instrument für die Planung von CoreMedia-Projekten und ein zentrales Element des Vorgehensmodells, das sowohl iterative als auch nicht-iterative Aktivitäten beinhaltet.
Field-Dependent Introverts, Extraverts and Psychological Health

Fine (1972) reported several studies indicating the existence of an antagonistic or unhealthy relationship between Eysenck's introversion and Witkin's field-dependence dimensions. Those individuals who scored both as introvert and field-dependent on appropriate psychological measures also scored significantly higher on neuroticism than those who scored any other combination of introversion-extraversion and field-dependenceindependence. The present study extends Fine's work into the area of psychological health qua self-actualization. Stemming from a previously published study (Doyle, 1975), those individuals who scored extreme field-dependent, i.e., one sigma above the Rod-and-frame Test mean (M = 4.20, SD = 3.02) and had either extraversion scores on the Eysenck Personality Inventory (Eysenck & Eysenck, 1968) of 13 or above (extraverts, n = 16) or extraversion scores of 7 or less (introverts, n = 5) became the target sample. The fielddependent introverts obtained a significantly higher neuroticism score (M = 17.00. SD = 3.41) than the field-dependent extraverts (M = 10.67, SD = 6.27; tip = 2.09, p < .05), which is consistent with Fine's hypothesized unhealthy relationship between introversion and field-dependence. With respect to the field-dependent extraverts' and introverts' scores on the Personal Orientation Inventory (Shostrom, 1966), an objective measure of self-actualization, all of Shostrom's scales were higher, i.e., more self-actualizing, for the field-dependent extraverts save the Feeling reactivity (Fr) and Nature of man constructive (Nc) scales. Three Personal Orientation Inventory scales were significantly higher (p < .O5) for the field-dependent extraverts' group, those of Time competence (TC), Existentiality (Ex), and Self-acceptance (Sa). From this it appears field-dependent extraverts tend to be relatively more content and at ease in their present life situation, more flexible in their coping strategems with novel situations, and more likely to accept their perceived human frailties than are field-dependent introverts. Thus, the present study appears to confirm to a limited degree Fine's thinking that field-dependent extraverts are more likely to experience less personal conflict qua neurosis and are more likely to exhibit various personal characteristics considered to evidence psychological health qua self-actualization than field-dependent introverts.
Human neural stem cells genetically modified to overexpress brain‐derived neurotrophic factor promote functional recovery and neuroprotection in a mouse stroke model

Intracerebral hemorrhage (ICH) is a lethal stroke type; mortality approaches 50%, and current medical therapy against ICH shows only limited effectiveness, so an alternative approach is required, such as stem cell‐based cell therapy. Previously we have shown that intravenously transplanted human neural stem cells (NSCs) selectively migrate to the brain and promote functional recovery in rat ICH model, and others have shown that intracerebral infusion of brain‐derived neurotrophic factor (BDNF) results in improved structural and functional outcome from cerebral ischemia. We postulated that human NSCs overexpressing BDNF transplanted into cerebral cortex overlying ICH lesion could provide improved survival of grafted NSCs and increased angiogenesis and behavioral recovery in mouse ICH model. ICH was induced in adult mice by injection of bacterial collagenase into striatum. The HB1.F3.BDNF (F3.BDNF) human NSC line produces sixfold higher amounts of BDNFF over the parental F3 cell line in vitro, induces behavioral improvement, and produces a threefold increase in cell survival at 2 weeks and 8 weeks posttransplantation. Brain transplantation of human NSCs overexpressing BDNF provided differentiation and survival of grafted human NSCs and renewed angiogenesis of host brain and functional recovery of ICH animals. These results indicate that the F3.BDNF human NSCs should be of great value as a cellular source for experimental studies involving cellular therapy for human neurological disorders, including ICH. © 2010 Wiley‐Liss, Inc.
Improved Particle Filters for Vehicle Localisation

The ability to track a moving vehicle is of crucial importance in numerous applications. The task has often been approached by the importance sampling technique of particle filters due to its ability to model non-linear and non-Gaussian dynamics, of which a vehicle travelling on a road network is a good example. Particle filters perform poorly when observations are highly informative. In this paper, we address this problem by proposing particle filters that sample around the most recent observation. The proposal leads to an order of magnitude improvement in accuracy and efficiency over conventional particle filters, especially when observations are infrequent but low-noise.
A waveform engineered power amplifier design for envelope tracking

A novel load network design for limited harmonic manipulations to implement a transmission line waveform engineered radio frequency power amplifier for LTE applications is presented in this paper, with the target to achieve quasi-linear efficiency during power back-offs with harmonic iteration. The topology selection was based on accurate large signal modeling and simulation to obtain optimum microstrip line design controlling the 2nd and 3rd order harmonics at the transistor output terminal. The design was implemented using the Cree CGH40010F GaN HEMT at 2.14GHz. It provides a continuous wave (CW) drain efficiency of 73.7% at a saturated output power of 40.7dBm at a fixed 30V supply, but it was optimized for linearization with LTE 64QAM 20MHz modulated signal with a power-added efficiency (PAE) of 42.7% at an average output power of 34.9dBm with linearity meeting 3GPP specifications, as well as envelope tracking with almost 70% power added efficiency from the same PA.
Data Mining and Intrusion Detection Systems

The rapid evolution of technology and the increased connectivity among its components, imposes new cyber-security challenges. To tackle this growing trend in computer attacks and respond threats, industry professionals and academics are joining forces in order to build Intrusion Detection Systems (IDS) that combine high accuracy with low complexity and time efficiency. The present article gives an overview of existing Intrusion Detection Systems (IDS) along with their main principles. Also this article argues whether data mining and its core feature which is knowledge discovery can help in creating Data mining based IDSs that can achieve higher accuracy to novel types of intrusion and demonstrate more robust behaviour compared to traditional IDSs.
Extravasation of hyperalimentation into the spinal epidural space from a central venous line

A 7-week-old ex-33-week girl developed fever and seizure. Blood and urine cultures were negative. Lumbar puncture revealed milky-white fluid with normal laboratory values except an elevated glucose (8,867 mg/dL, nl 40 to 70 mg/dL). Abdominal x-ray revealed migration of …