Miracle-dz/UniFAR-FTUs huggingface dataset:
Automatic distribution analysis of business processes forcloud-based BPM

Business Process Management (BPM) has been used to organize, visualize, analyze, optimize and continuously improve the business processes of organizations. BPM supports the composition of Service-Oriented Architecture (SOA) services and human tasks into complete organizational business processes at the level of business process modeling. Many of these business process models involve several on-premise computation-intensive activities and data, requiring expensive massive computing power and data storage. In recent years, cloud computing emerged to offer opportunities, such as reducing the upfront investments in infrastructure and taking advantage of a vast amount of cheaper computational capacity and data storage resources. As a result, organizations considered migrating total or parts of on-premise business processes to cloud-based BPM as a favorable alternative for business process improvement. However, organizations face challenges regarding the identification and selection of distribution options of business processes into collaborating in-cloud and on-premise engines considering multiple cloud migration decision factors, such as cost benefits and privacy risks. Our main research objective in this thesis is to identify the most relevant cloud migration drivers and barriers, investigate how they should relate to business processes, and define algorithms that can be used to automatically identify and rank distribution options for Cloud-based BPM. The results of our research facilitate the automatic identification and selection of distribution options of business processes into collaborating in-cloud and on-premise engines, and their consequences. As a proof-of-concept implementation, we have developed an annotation language and automated system for identifying and ranking distribution options of business processes and their consequences by representing cost benefits and privacy risks for Cloud-based BPM in the BiZZdesign Architect modeling tool.
Ilkka Pietilä THE ROLE OF DKK 1 AND WNT 5 A IN MAMMALIAN KIDNEY DEVELOPMENT AND DISEASE

This thesis focuses on mammalian kidney development and in particular on the question of how two Wnt signalling pathway genes, an antagonistic Dkk1 and an agonistic ligand Wnt5a, regulate the process. Wnts are secreted ligands that are involved in many developmental processes, including gonadal differentiation and kidney development, but also in various diseases and malformations. Wnts form a large signalling family containing 19 different glycoprotein ligands in mammals. Wnt signalling occurs via two different intracellular pathways. A canonical pathway proceeds via betacatenin, and a non-canonical pathway utilizes other signalling molecules. Dkk1 is an antagonist of the canonical pathway and Wnt5a is considered a ligand that activates the non-canonical signalling pathway. As part of the thesis, I have studied the role of Dkk1 in kidney morphogenesis using a conditional mouse model, in which the gene is deleted in a cell specific manner from the collecting ducts. Dkk1 deficiency increased renal papilla growth and the risk of hydronephrosis. Research pointed out that the lack of Dkk1 in the collecting ducts increased cell proliferation and disturbed the balance of canonical Wnt signalling, which led to an overgrowth of renal papilla. This led to functional phenotypes including increased water reabsorption and changes in ion secretion/ absorption. These changes are most likely due to altered Wnt7b signalling. The second part of the thesis examines the role of the non-canonical Wnt5a gene in kidney development with a conventional knock out mouse model. At the time work began on the thesis, no corresponding kidney phenotype had been published. The primary finding in kidneys lacking Wnt5a was an altered basement membrane organization of the collecting ducts and glomeruli. The phenotype is most likely the reason behind morphological phenotypes which vary from bilateral kidney agenesis to duplex collecting system. Notably, during the course of this study we found a mutation in the human WNT5A gene of a CAKUT patient. This is the first time Wnts have been shown to organize kidney development via basement membrane formation.
Modifying Cardiovascular and Metabolic Risk Factors: The Role of the Endocannabinoid System and Cannabinoid Receptors GUEST EDITOR

Louis J. Aronne, MD Clinical Professor of Medicine Weill Medical College of Cornell University Columbia College of Physicians and Surgeons Director, Comprehensive Weight Control Program New York–Presbyterian Hospital New York, New York Daniel J. Rader, MD Professor of Medicine, Pharmacology, and Pathology Director, Preventive Cardiovascular Medicine and Lipid Clinic Director, Cardiovascular Metabolism Unit Institute for Diabetes, Obesity, and Metabolism University of Pennsylvania School of Medicine Philadelphia, Pennsylvania
A comparison of the effectiveness of behavioral management training to parents and the children narrative therapy on reducing the symptoms of Attention Deficit / Hyperactivity Disorder

According to the clinical importance of the Attention Deficit, Hyperactivity Disorder is one of the most common neural-behavioral disorders in children as well as its impact on the family system. This study is aimed at comparing effectiveness of the behavioral management training to parents and narrative therapy on symptoms of the children who are afflicted by the Attention Deficit/ Hyperactivity Disorder. This quasi experimental study is of the pretest-posttest with the control group . Statistical community included all of the children, out of 30, suffered from ADHD, between 7 to 12 years old, in the city of Sari, in companion with their mothers, who were selected and assigned to three groups. The first group, received 8 sessions of narrative therapy, the second one received 9 sessions of behavioral management training to mothers based on Barkley’s model, and the third group, received nothing. Parental Stress Index Test was utilized in order to collect data, and analyzing data fulfilled in the form of analysis of variance. The results showed that there is a significant difference between the treatment groups of behavioral management training to parents and the narrative therapy. Conclusion: Findings of the study shows that the method of narrative therapy is more effective in reducing the symptoms of Attention Deficit /Hyperactivity Disorder and this therapeutic approach can be utilized as well as the pharmacotherapy.
DOES DEFENCE SPENDING STIMULATE ECONOMIC GROWTH IN INDIA? A REVISIT

This study reinvestigates the effect of defence spending on economic growth using Zivot and Andrews and Lee and Strazicich, structural unit root tests and the autoregressive distributed lag bounds testing approach to cointegration in augmented version of Keynesian model for India. Study confirmed long run relationship among variables studied show that economic growth is positively affected by defence spending (also negative impact after a threshold point), investment and trade openness while negatively by interest rate. Granger causality analysis revealed bidirectional causal relationship between defence spending and economic growth as probed by variance decomposition approach.
Testing a climate erosive forcing model in the Po River Basin

Changes in the spatial and temporal features of precipitation patterns may have important effects on the magnitude and timing of erosive rainfalls, which will in turn result in changes in soil degradation response. This study presents a secular timescale environmental hazard assessment to account for the impacts of climate erosive forcing on an agricultural landscape identified as potentially vulnerable, mainly to erosional soil degradation processes. An empirical probabilistic model for temporal characterisation of this impact, termed CHIEF (Climate Hazard Index Erosive Forcing), was developed to evaluate the annual balance between climate driving and climate resisting forces in the Po River Basin (northern Italy) during the period 1775 to 2003. In the CHIEF approach, an ecological system adapted to the natural hydro-climatic regime was assumed; fluctuations in this regime, especially those exceeding thresholds of rainfall energy intensity, may trigger erosional soil degradation processes. In this way, the time sensitivity of the CHIEF model reflects the magnitude of annual input nested within patterns of long-term environmental change occurring within a specific temporal window, in order to capture different modes of climatic variability and their hydro-geomorphological implications.
Writing ability in children suffering from cerebral palsy after phased fiberotomy: Case report

Writing is a complex ability which includes a series of different abilities and activities which have to interact during writing. Successful writing is achieved only if all of these abilities and processes function and if, during the learning phase, their full interactivity is achieved. Cerebral palsy doesn't have a single typical clinical manifestation. It is specific to each individual in relation to: the etiology of brain damage, localization and size of defects, and the period in which the damage occurred. Given these facts, the assessment of a child with cerebral palsy should be based on the potential estimate model and through profiles of achievements in certain areas, and the qualitative and quantitative interpretation. The aim of this study is to assess the writing skills of a boy who had undergone surgery of phased fiberotomy. For the assessment of writing, through qualitative analysis, we used the "Scale for assessment of handwriting dysgraphia" (Ažiriagera, Ozias), according to Cordic and Bojanin (1997).
Current Contribution of Four Biotechnologies to New Zealand's Primary Sector

Over the last several decades, changes to production technologies have significantly increased output from the primary sector. The contribution of improved genetics has been variously estimated, and the impacts of genetic engineering have received much attention. The present research estimated the economic impact of four modern biotechnologies (other than genetic engineering) on the primary sector. Information from interviews with key informants was incorporated into a cost-benefit analysis to estimate these impacts. The net contribution was estimated at $266 million per year, with impacts spread unevenly through the sector and across biotechnologies.
eu COLUMN MEAN VANISHING MATRICES

In this paper, we study some properties of a special class of matrices having orthonormal columns. These matrices appear in some applications, especially in wireless communications. We study the column property and spectral decomposition. Using these properties, we suggest a new method of generating such matrices. For N even, the new method gives rise to a matrix which is more efficient. Numerical examples to compare two methods are included. AMS Subject Classification: 65N15, 65N30, 35J60
Genomic DNA extracted from long preserved silkmoth samples suitable for genetic diversity studies

In the present study, preserved silkmoths served as samples for DNA extraction. The wings, legs and antennae of moths were cut with sterile scissors before preservation of the samples. The samples were placed in airtight cryovials snap frozen in liquid nitrogen and immediately stored at -80 0C for further use. Genomic DNA was isolated after six months from the frozen silkmoth samples, crushed under liquid nitrogen which yielded high molecular weight DNA. RAPD profile of the isolated DNA revealed high degree of polymorphism. The silkworm strains were analyzed using 6 random primers out of which 5 polymorphic primers gave 61 amplicons. The average amplicons per primer found to be 10.16 and 73.02% amplicons were polymorphic. Cluster analysis based on Jaccard’s similarity coefficients resulted in the formation of two main clusters with SKAU-R-1,CSR18, SH6 and NB4D2 in one cluster and the remaining two genotypes viz., CSR2 and DUN22 in other cluster. Jaccard’s similarity coefficients ranged from 0.97 to 0.99 indicating considerable genetic diversity within bivoltine silkworm groups. Isolated genomic DNA from silkmoths was found suitable to undertake genetic diversity studies using molecular marker approach for identifying diverse genotypes for taking up breeding programs to push up bivoltine silk production
Establishment Processes and Building Relationships in Latin American Countries : The Case of Swedish Firms in Mexico

This paper addresses the establishment processes of two Swedish companies in the auto- motive industry in Mexico by applying an establishment process model. An exploratory case study is applied as a research method. One of the main findings of the article is that in both bus and truck segments (sectors), there are well developed and tightly structured networks which function more or less in the same way as the networks and relationships in developed countries although Mexico is a developing country. Another finding is that the level of trust with the Scania's customers differs in the two segments. In the bus segment the relationship with customers is dominated by cooperation and trust, whereas in the truck segment it does not as the market has more trust in other brands than in Scania's products and services. A third finding is that Scania's competitive advantages rely on its complete solution which includes trucks, parts and services and on its cooperation with some com- petitors and strong relations with authorities. While Volvo's competitive advantages are based on its strong dealers network strengthened through complete solution including training, new financing and selling programs, i.e. offering integrated services and cooperation with some competitors and strong relations with authorities. A fourth finding is that in the Mexican market, government relationships are as important as customer relations and should be dealt with adequately if firms are going to succeed in their establishment attempts.
Employee Representation and Consultative Voice in Multinational Companies Operating in Britain

Multinational companies (MNCs) from different countries of origin are widely held to have distinct preferences regarding the presence of employee representative structures and the form that employee ‘voice’ over management decisions takes. Such preferences are said to derive from the national models that prevail in the different countries of origin in which MNCs are based. Findings from a large-scale survey of the UK operations of MNCs indicate that country-of-origin influences on patterns of employee representation and emphasis on direct or indirect channels of employee ‘voice’ are attenuated by other factors, notably sector and method of growth. They also reveal significant recent innovation in representation and voice arrangements by this key group of employers.
Banking crises, R&D investments and slow recoveries

This paper studies how banking crises affect the composition of corporate investments and economic growth. Theoretically, it builds a partial equilibrium endogenous growth model with a banking sector and aggregate shocks. In the model, entrepreneurs can invest in two types of technologies: a safe, short-term one and an innovative, long-term one. Long-term projects are growth-enhancing but subject to a liquidity cost which credit constrained entrepreneurs cover by borrowing from the banking sector. When bank creditors are sufficiently pessimistic about the aggregate liquidity needs of the real sector, they will run on the bank and cause a credit freeze. This liquidity crisis disrupts real sector investments which reduces returns and tightens credits constraints in the next period. Furthermore, tighter credit constraints after the crisis decrease the share of entrepreneurs’ investments in innovative projects, which slows down growth. Industry-level data on R&D investments following 13 recent banking crises episodes support this hypothesis. I show that industries that depend more on the banking sector reduce their R&D spending disproportionately more following episodes of banking distress, confirming the hypothesis that at least part of this effect is caused by a credit supply channel. JEL Classification: G01, G21, E22
Modulation of the W748S mutation in DNA polymerase γ by the E1143G polymorphism in mitochondrial disorders

DNA polymerase gamma (pol γ) is required for replication and repair of mitochondrial DNA. Over 80 mutations in POLG, the gene encoding the catalytic subunit of pol γ, have been linked with disease. The W748S mutation in POLG is the most common mutation in ataxia-neuropathy spectrum disorders and is generally found in cis with the common E1143G polymorphism. It has been unclear whether E1143G participates in the disease process. We investigated the biochemical consequences of pol γ proteins containing W748S or E1143G, or both. W748S pol γ exhibited low DNA polymerase activity, low processivity and a severe DNA-binding defect. However, interactions between the catalytic and accessory subunits were normal. Despite the benefits derived from binding with the accessory subunit, catalytic activities did not reach wild-type (WT) levels. Also, nucleotide selectivity decreased 2.1-fold compared with WT. Surprisingly, pol γ containing only E1143G was 1.4-fold more active than WT, and this increased polymerase activity could be due to higher thermal stability for E1143G pol γ. The E1143G substitution partially rescued the deleterious effects of the W748S mutation, as DNA binding, catalytic activity and fidelity values were intermediate for W748S-E1143G. However, W748S-E1143G had a notably lower change in enthalpy for protein folding than W748S alone. We suggest that when E1143G is in cis with other pathogenic mutations, it can modulate the effects of these mutations. For W748S-E1143G pol γ, the benefits bestowed by E1143G include increased DNA binding and polymerase activity; however, E1143G was somewhat detrimental to protein stability.
Simulation Model to the Zika Virus Considering Asymptomatic Population

A simulation model based on nonlinear ordinary differential equations to interpret the transmission dynamics of Zika Virus (ZIKV), is formulated and analyzed, integrating the asymptomatic human population and coupled to the Aedes aegypti dynamics, the epidemic threshold Basic Reproduction Number R0 is determined, as the spectral radius of Next-Generation Matrix and the system is simulated with MAPLE computing program taking the parameter values from literature.
Comparative Pharmacognostical and Pharmacological Evaluation of two Achyranthes species

Introduction: Achyranthes is a well-known herb used in folk lore and traditional systems of medicine for its therapeutic value. The two species Achyranthes aspera and Achyranthes bidentata are used interchangeably by people and by herbal industries due to their resemblance in appearance. Therefore, the present study was undertaken to evaluate the comparative pharmacognostic and pharmacological properties of both species. Methods: Pharmacognostic characters were evaluated as per the guidelines of Ayurvedic Pharmacopoeia of India. A quantitative HPTLC method was developed for quantification of linoleic acid and oleanolic acid using toluene: ethyl acetate: formic acid (6: 4: 0.5 v/v/v) as a mobile phase. Quantification was performed using linear regression analysis by plotting the peak area vs concentration curve with 2000-5000 ng/band (R2 = 0.998) for oleanolic acid and 2000-5000 ng/band (R2 = 0.994) for linoleic acid. The developed method was validated in terms of accuracy, recovery and inter and intraday study as per ICH guidelines. Antioxidant activity of methanolic extracts was estimated by five different models viz. DPPH free radical scavenging assay, total anti-oxidant capacity, reducing power assay, total flavonoid and phenol content. Anti-diabetic activity was analyzed by α-amylase inhibition assay using 3, 5 di nitro salicylic acid and iodine starch model. Results: The limit of detection (LOD) and limit of quantification (LOQ) of oleanolic acid and linoleic acid were determined, respectively, as 0.426, 1.29 and 0.427, 1.29 μg mL−1. Inhibition of free radicals increases with concentration and IC50 of A. aspera and A. bidendata was obtained at 1.35 ± 0.173 mg/ml and 1.28 ± 0.169 mg/ml respectively. In in vitro antidiabetic activity, IC50 value shows that A. bidentata exhibit better activity than A. aspera. Conclusion: The present study generates data for the proper establishment of quality control standards of the crude drug.
EFFECT OF REDUCTION TIME ON OPTICAL PROPERTIES OF REDUCED GRAPHENE OXIDE

Graphene and its’ derivatives received tremendous attention. The characteristics and properties of graphene made the material suitable to be used in many applications such as polymer composites, transistors and sensors. Graphene oxide (GO) and reduced graphene oxide (rGO) are few examples of graphene derivatives. GO can be synthesized in many ways. In this study, GO was produced via modified Hummer’s method. Meanwhile, sodium borohydride (NaBH 4 ) is chosen as a reductant to further reduce the GO via chemical reduction. The material was characterized using FT-IR, UV-Vis and FESEM to observe the characteristics which occurred during the reduction process. From the FT-IR spectrum it is clearly shown that the carbonyl (C=O) and epoxy groups were eliminated on rGO. On the other hand, the band gap value of rGO reduced gradually as the reduction time increase. Besides that, the morphology of GO and rGO was also compared under the magnification of 2500x.
Use of Domestic effluent through duckweeds and red tilapia farming in integrated system

The present study aimed to evaluate duckweeds for wastewater treatment and as an alternative dietary feed source for tilapia in a reuse pilot system. Duckweeds presented a satisfactory pollutants removal, mainly for chlorophyll “a” (99.9±2.7%), suspended solids (67.2±13.6) and turbidity (90.3±20.0%), reaching adequate criteria for aquaculture (nitrite, nitrate and COD concentrations under acceptable levels). Duckweed average production registered could reach up to 38.17 t/ha/year (dry matter), with a crude protein and fiber content of 38.03% and 16.17%, respectively. Fish fed on commercial feed presented higher growth performance compared to fish fed on dried duckweed. Final weight, feed conversion rate and specific growth rate of tilapia fed on dried duckweed were 52.5g, 4.3 and 1.17%, respectively. For commercial feed, the values found were 85.7g, 2.6 and 2.24%. Microbiological analysis confirmed that fish reared in treated wastewater were free of pathogenic organisms. Therefore, production of duckweed in wastewater can be an alternative which contributes to the sustainability of sewage treatment plants, mitigating environmental impacts. Also, it can be an alternative dietary source for tilapia, reducing feeding expenses as a mixture of dried duckweed and commercial feed (1:1) could reduce its production costs.
ADVANTAGES OF CLONAL FORESTRY FOR PINUS RADIATA — REAL OR IMAGINED?

The advantages of using tested clones in Pinus radiata D. Don forests were compared with current open-pollinated and control-pollinated seed orchard strategies. Clonal forestry shares with control-pollinated orchard strategies advantages of shorter plant production times, control of pedigree, flexibility of deployment, multiplication of valuable crosses, and efficient capture of additive genetic gains. It may have additional advantages in increasing uniformity, allowing clone/site matching, controlling growth habit, and capturing nonadditive genetic gains. However, a control-pollinated orchard strategy coupled with vegetative multiplication is currently proving to be more cost-efficient in establishing managed stands. Use of a clonal strategy requires evidence for greater economic gains.