Miracle-dz/UniFAR-FTUs huggingface dataset:
Drive For Muscularity in Male Adolescents: The Role of Psychological Factors (Self-Esteem, Maladaptive Perfectionism, and Interpersonal Sensitivity)

Background: Concerns about body image among male adolescents has become increasingly prevalent, leading to a need for muscularity. It is well known that psychological factors play a role in the development of these concerns. Objectives: The aim of the current study was to predict the drive for muscularity based on psychological factors, including self-esteem, maladaptive perfectionism, and interpersonal sensitivity. Methods: This cross-sectional study was conducted in 2019. Using a convenience sampling method, 150 adolescent male students from district 14 of Tehran, Iran, were selected to participate in the study. Data was collected by utilizing the following measures: drive for Muscularity scale, Rosenberg Self-Esteem scale, Almost Perfect scale-revised, and Interpersonal Sensitivity measure. Data were analyzed using the Pearson correlation coefficient and the Enter Regression method. Results: High scores in the Drive for Muscularity scale were significantly associated with higher levels of maladaptive perfectionism, interpersonal sensitivity, and lower levels of self-esteem. Moreover, the results of the multiple regression analysis revealed that predivariables could explain 52% in the variance of the drive for muscularity. Conclusions: Findings indicated that the psychological factors investigated in this study were risk factors for masculinity among adolescents. We suggest that clinicians take these factors into account in order to make preventive and therapeutic programs more effective.
Suriyeli Öğrenciler İçin Görevlendirilen PICTES Öğretmenlerinin Tükenmişlik Düzeyleri: Bursa Örneği

Suriyeli cocuklarin egitim ihtiyacinin karsilanmasi ve okullarda karsilastiklari dil probleminin cozulmesi adina Avrupa Birligi destegi ile Milli Egitim Bakanligi tarafindan baslatilan PICTES projesi, ogretmen istihdami icin yeni bir alan olmustur. Bu calismanin amaci, PICTES ogretmenlerinin tukenmislik duzeyini; brans, okul turu ve ogrenci sayisi degiskenlerini goz onune alarak belirlemektir. Bu baglamda Bursa’da gorev yapan 148 PICTES ogretmenine Maslach Tukenmislik olcegi uygulanmis ve 17 ogretmenle yari yapilandirilmis gorusme yapilmistir. Calismada nicel ve nitel veriler es zamanli toplanmistir. Once nicel asama ile ilgili analizler, Kruskal-Wallis-H testi kullanilarak gerceklestirilmistir. Ardindan katilimcilarin tukenmislikle ilgili siraladiklari nitel veriler icerik analizine tabi tutulmustur. Arastirmanin sonucunda PICTES ogretmenlerinin duygusal tukenme alt boyutunda orta, duyarsizlasma alt boyutunda yuksek, kisisel basarisizlik alt boyutunda ise yuksek duzeyde tukenmislik yasadigi saptanmistir. Bu calismanin henuz mesleklesme surecinde olan yabanci uyruklu ogrenci egitimine ve bu yonde yapilan egitim planlamalarina katki saglayacagi dusunulmektedir.
Combined locoregional and systemic therapy for advanced hepatocellular carcinoma: finally, the future is obscure

Department of Interventional Radiology, Dotter Interventional Institute, Oregon Health and Science University, Portland, OR, USA; Department of Radiation Oncology, Oregon Health and Science University, Portland, OR, USA; Division of Hematology and Medical Oncology, Department of Internal Medicine, Oregon Health and Science University, Portland, OR, USA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Oregon Health and Science University, Portland, OR, USA Correspondence to: Khashayar Farsad. Dotter Department of Interventional Radiology, 3181 SW Sam Jackson Park Road, L-605, Portland, OR 97239, USA. Email: farsad@ohsu.edu. Comment on: Kim BK, Kim DY, Byun HK, et al. Efficacy and Safety of Liver-Directed Concurrent Chemoradiotherapy and Sequential Sorafenib for Advanced Hepatocellular Carcinoma: A Prospective Phase 2 Trial. Int J Radiat Oncol Biol Phys 2020;107:106-15.
DEVELOPING ITEMS FOR MEASURING QUALITY OF WORK LIFE AMONG MALAYSIAN ACADEMICS: AN EXPLORATORY FACTOR ANALYSIS PROCEDURE

Purpose of the study: Quality of work life (QWL) is vital for all establishments to continue to hire and retain high-performance workers. However, from the review of previous literature on QWL, little is known about the dimensions that constitute high QWL among academics. Therefore, this study aimed at contributing to the literature by conducting a detailed validation of seven dimensions of QWL through the Exploratory Factor Analysis (EFA) procedure. Methodology: This study employed a cross-sectional research design to establish reliable measures for the QWL construct. The items were adapted and modified to suit this study. Study data was obtained using a structured questionnaire from 100 randomly selected academics from the five Malaysian research universities. The study further conducted the Exploratory Factor Analysis (EFA) procedure using IBM-SPSS version 21.0. Main Findings: A total of 51 items were initially developed to measure QWL construct, however, from the EFA procedure, the study found that 8 items with factor loading below the cut-off point of . 60 were deleted and 48 items with a factor loading above the cut-off point of . 60 were retained and deemed suitable to measure the QWL construct. Applications of this study: This study validated the dimensions that lead to improved QWL. Therefore, this study is particularly useful to the Malaysian universities' management who aim to obtain benefits from super motivated and high-performance academics by making sure that the workers' overall well-being is protected in the workplace. Novelty/Originality of this study: This study established a validated and reliable instrument for measuring the QWL construct among academics in the Malaysian research universities.
Novel Therapeutic Targets and Biomarkers for the Treatment of Progressive Supranuclear Palsy

Progressive supranuclear palsy (PSP) is a sporadic parkinsonism tauopathy characterised by the deposition of aggregations of abnormal, hyperphosphorylated four-repeat tau (4R-tau). A revised clinical diagnostic criterion for PSP allows early presentations for the full spectrum of clinical phenotypes to be recognised enabling doctors to make a more accurate diagnosis. The major genetic risk factor for sporadic PSP is a common variant in the gene encoding microtubule-associated protein tau (MAPT). Research into the biochemical and pathological pathways of tau is vital to improve the chances of developing an effective diagnostic biomarker to monitor tau pathogenesis. Neuroimaging biomarkers, such as tau PET ligands, are proving the most successful tool in providing a differential diagnosis between neurodegenerative disorders. There are currently no effective treatments for PSP, however tau-directed therapies in the last five years have rapidly advanced. Latest tau therapies are proposed to have disease-modifying effects by reducing toxic aggregations of tau through manipulating tau gene expression. After encouraging results from long awaited trials, additional funding is being injected into this field and with new results expected, this proves an exciting area for scientific discovery. This paper reviews advances in pathophysiology, diagnosis, biomarkers and disease-modifying therapeutic treatments for PSP.
Multiple Functions Of The Striated Rootlet Proteins Of The Paramecium Basal Body

i Acknowledgements . ii List of Tables . vi List of Figures . vii Chapter 1: Comprehensive Literature Review . 1 I. General overview . 1 Motility and behavior of the Paramecium tetraurelia . 2 Cilia and basal bodies . 3 Basal body duplication in Paramecium . 5 Cortex of the Paramecium and the associated structure . 7 Intraflagellar transport (IFT) . 10 Ciliopathies . 12 II. Experimental approaches . 15 RNA interference . 15 Expression of exogenous protein in Paramecium . 17 iv Isolation of SRs . 18 Experimental Approach for the SR project . 19 Chapter 2: Multiple functions of the Striated Rootlet (SR) proteins of the Paramecium basal body . 30 Introduction . 30 Materials and Methods . 34 Results . 47 Discussion . 66 Chapter 3: Depletion of MKS5 causes loss of cilia but does not affect the basal body rows straight alignment . 156 Introduction . 156 Materials and Methods . 161 Results . 168 Discussion . 172 Chapter 4: Concluding remarks . 187 References . 200
A Person-Centered Approach to Examining Polytraumatization Among Traumatized and Bereaved Youth

Abstract The current study examined how polytraumatization classes predicted mental health outcomes among a sample of treatment-seeking, traumatized, and bereaved youth. A latent class analysis identified that a four-class model with the following classes fit the data best: Violence-Exposed, characterized by exposure to community violence and bereavement by homicide (11.1%), Polytrauma, characterized by exposure to multiple types of trauma (16.5%), Long-Term Illness Bereavement, characterized by bereavement by long-term illness (21.1%), and Sudden Bereavement, characterized by bereavement by short-term illness or accident (51.3%). Preliminary analyses identified older children in the Polytrauma class, more girls in the Long-Term Bereavement class, and more Black youth in the Violence-Exposed class. The Polytrauma class was characterized by higher rates of posttraumatic stress symptoms; however, classes did not differ significantly on maladaptive grief, depression, or suicidality. Results highlight the importance of considering subgroups of traumatization among highly traumatized and bereaved youth when implementing mental health screening and treatment.
The Effect of nest Size and Species Identity on Plant Selection in Acromyrmex Leaf-Cutting Ants

Leaf-cutting ants are key organisms because their role as primary consumers and potential agricultural pests. However, their foraging ecology was mostly studied as response of extrinsic factors such as climate and plant species traits. We evaluated the effects of intrinsic factors (i. e., nest size and species identity) on the foraging behavior in two species of Acromyrmex Mayr leaf-cutting ants. While large and small nests of A. lobicornis Emery showed similar feeding behavior, small nests of A. striatus Roger harvested a greater percent of the plant species available in their foraging area and showed a higher level of selectivity than larger nests. We discussed some probable reasons for this pattern. Our results highlight the relevance of intrinsic factors and species characteristics to explain changes in the foraging ecology of leaf-cutting ants as colony growth.
Efecto de un programa de entrenamiento de fuerza sobre IGF-1 en adultos mayores con obesidad e hipertensión controlada (Effect of a strength training program on IGF-1 in older adults with obesity and controlled hypertension)

Introduction: As people age, muscles decrease in size and strength. Loss of muscle mass can cause a general decrease of metabolic function associated with low anabolic hormone production and risk of injury. The decrease in serum levels of GH and IGF-1 due to aging can provoke fragility by contributing to the loss of muscle mass and strength. Purpose: To determine the effect of a strength training program on IGF-1 in older adults with obesity and controlled hypertension. Method: a sample of 8 older adults with obesity and controlled hypertension performed 6 weeks of strength training with intensities of 70% 1RM and 10RM, with a frequency of 4 times per week. Prior to the protocol of Training, triglycerides, cholesterol, blood glucose IGF-1, and anthropometric measures (size, weight, % fat and muscle mass) were determined. The test of one maximum repetition (1rm) was performed to evaluate maximum force in upper and lower limbs before and after the training program. Results: A significant increase (p <0.05) was observed in serum IGF-1 levels after the completion of training program. Conclusion: Strength training with intensities of 70% of 1RM and frequency of 4 days/week, carried out for 6 weeks, produced increases in serum IGF-1 concentration and increased muscle strength in older adults with obesity and controlled hypertension.
Effect of Yoga on Memory in Elderly Women

Introduction: Cognitive impairment rate such as memory loss increases because of aging as a natural process. Based on the evidence, physical activity can lead to improved mental and cognitive function and also plays a preventive role against reducing cognitive function. the purpose of this study was to investigate the effect of yoga exercises on memory of elderly women. Methods: This experimental study was a randomized, controlled clinical trial that was conducted in 2018. Two elderly day care centers in Yazd city ,in central Iran were selected and randomly assigned to control and intervention groups. Then, according to the inclusion criteria, eligible people were selected from the centers and enrolled in the study. Participants were 58 elderly women who were assigned to control (n: 29) and intervention (n: 29) groups. Yoga exercises were held for 2 months (three 1-h sessions a week) for intervention group. The Wechsler Memory Scale was completed for both groups before and after the intervention. Data were analyzed by SPSS using descriptive and inferential statistics. Results: The mean score of memory in the intervention group before intervention was 77.7 ± 17.8 and after the intervention reached 86.4 ± 17.3, with a statistically significant difference (p < 0.05), but in control group, no significant difference was observed. In the intervention group, mental control, logical and visual memory subscales increased significantly (p < 0.05), but there was no significant difference in other subscales. There was no significant difference in any of the subscales in control group (p > 0.05). Conclusion: To improve the memory of the elderly, physical activity such as yoga exercise can be helpful. The elderly can routinely practice these exercises in elderly care centers.
Analysis of Architecture Combining Convolutional Neural Network (CNN) and Kernel K-Means Clustering for Lung Cancer Diagnosis

In this paper, we proposed the modified deep learning method that combined Convolutional Neural Network (CNN) and Kernel K-Means clustering for lung cancer diagnosis. The Anti-PD-1 Immunotherapy Lung dataset obtained from The Cancer Imaging Archive was used to evaluate our proposed method. From this dataset, we use 400 Magnetic Resonance Imaging (MRI) images that manually labeled consists of 150 healthy lung images and 250 lung cancer images. As the first step, all the data was examined through the CNN architecture. The flatten neuron of the feature map for every image resulted from the convolutional layers in CNN is gained and passed through the kernel k-means clustering algorithm. This algorithm then used to obtain the centroid of each cluster that determines the prediction class of every data point in the validation set. The performance of our proposed method was evaluated using several k values in k-fold cross-validation. According to our experiments, our proposed method achieved the highest performance measure with 98.85 percent accuracy, 98.32 percent sensitivity, 99.40 percent precision, 99.39 percent specificity, and 98.86 percent F1-Score when using RBF kernel function with sigma=0.05 in 9-fold cross-validation. Those performance improves 1.31% sensitivity, 1.12% accuracy, 1.11% F1-Score, 0.92% specificity, and 0.91% precision compared to when using 5-fold cross-validation. It is even obtained in less than 8 seconds for passing the dataset to the CNN model and 40 ± 0.77 seconds for examined in kernel k-means clustering. Therefore, it was proved that our proposed method has an efficient and promised performance for lung cancer diagnosis from MRI images.
Intelligent Decision-Making Technology for Choice MVC Models using Neural Networks

Today, the development of any web application based on the MVC architecture can not be imagined without its main component-the model. The convenience and thoughtfulness of the created model allows you to improve the quality and speed of the task to be solved. However, today most developers use standard interface elements or self-written models, which leads to long development and possible synchronization problems. In order to ensure that you can quickly adapt and select your own set of user model elements for a specific task, you need to create an automated module that allows you to create software code models based on the MVC architecture. By using the MVC architecture, it is possible to separate the model from its visualization (representation, view). This separation increases the ability to reuse the code. The most useful application of this concept is when the user needs to see the same data simultaneously in different contexts and / or from different perspectives. As a result, the development of a software module that will automate the creation of models based on the MVC architecture is an urgent task.
The Effect of Work Discipline on The Use of Mobile Sales Force Automation System Usage

— Purpose : The purpose of this study is to examine and describe the effect of work discipline on the use of mSFA, the effect of work motivation on the use of mSFA, the effect of work tidiness on the use of mSFA, and the effect of using mSFA on discipline. Design / Method : This research is a quantitative study and the sampling technique is simple random sampling where the research sample has the same unlimited opportunity to be selected as a sample. The analytical method used in this research is descriptive analysis and GSCA analysis. Findings : job discipline has a significant effect on the use of mSFA, work motivation has a significant effect on the use of mSFA, the use of mSFA has a significant effect on the use of mSFA. To complete future studies, researchers may consider using objective data from the database system from before using the mSFA system until some time after using the mSFA system. Originality : The researcher also tries to determine the relationship between work discipline and the use of mSFA and work motivation to update previous studies. By combining variables that affect income and the impact of usage on individuals, this research method differs from previous studies.
Sequential choices using signal detection theory can reverse classical predictions

&NA; The behavioural sciences have been strongly influenced for several decades by signal detection theory (also known as “error management theory” and “ROC analysis”). The theory provides simple logic about how individuals should behave in order to maximize their expected payoff in a single decision; for instance, the theory predicts that as the probability of a particular danger increases, individuals should be more prone to avoiding that danger. However, such findings need not hold in situations where more than 1 decision will be made, and recent work has shown that when behavior is allowed to depend on the energy reserves of the individual, the classical predictions can be reversed. Here, we use a simple analytic technique to show that even when the same behavioral rules are used at every reserve level, the predictions of classical signal detection theory (as though only a single decision will be made) are often reversed in a world where autocorrelation is high. The classical predictions are reversed because individuals will often make multiple decisions to achieve a goal, and the outcome of an action can influence the number of subsequent decisions that are required. The finding suggests that fundamental predictions should be altered across many of the behavioral sciences, not only in relation to signal detection theory, but also other single‐decision models.
Glyphosate and Saflufenacil: Elucidating Their Combined Action on the Control of Glyphosate-Resistant Conyza bonariensis

Synergic effects of glyphosate and saflufenacil have been reported to control Conyza spp. However, the mechanism of this synergic combination is unknown. The objectives of this study were to investigate the effects of the combination of glyphosate and saflufenacil on the control and resistance status of glyphosate-resistant (GR) C. bonariensis, as well as on oxidative stress and lipidic peroxidation. Glyphosate-resistant and glyphosate-sensitive (GS) biotypes were treated with different rates of saflufenacil, glyphosate, and glyphosate combined with saflufenacil. The combination of glyphosate (1480 g ae ha−1) and saflufenacil (≥15 g ha−1) presented the best control of GR plants compared with their individual effects. It also reduced the resistance factor from 19.6 to 4.6 (4.3-fold) and represents a good alternative for resistance management. The combination of glyphosate and saflufenacil resulted in higher oxidative stress and lipidic peroxidation compared with the effects of either herbicide alone. The oxidative stress and lipid peroxidation promoted by the combination of the herbicides occurred earlier after treatment and remained at higher levels over a longer period (12–192 h) compared with their individual results. The combined oxidative stress and lipid peroxidation at high levels over a long time is likely to be one reason that the combination of glyphosate and saflufenacil effectively controls GR C. bonariensis.
Hydroglycerolic Solvent and Ultrasonication Pretreatment: A Green Blend for High-Efficiency Extraction of Salvia fruticosa Polyphenols

Salvia fruticosa Miller, also known as Cretan or Greek sage, is a medicinal plant with significant biological properties, which are largely ascribed to its polyphenolic composition, but there is to-date a scarcity of green and sustainable processes for efficient polyphenol extraction from this plant. The objective of this study was the implementation of an extraction process that would combine a green solvent based on glycerol, a biodiesel industry by-product, and ultrasonication pretreatment. Ultrasonication for 40 min followed by stirred-tank extraction was shown to provide significantly higher total polyphenol yield than mere stirred-tank extraction, while kinetics indicated 50 °C as the most favorable temperature, with the yield being 92 mg gallic acid equivalents (GAE) per g dry mass. Comparison of this method with a previously developed one that used methyl β-cyclodextrin revealed that the extracts obtained had similar antioxidant activity, and yield in major polyphenols including luteolin 7-O-glucuronide and rosmarinic acid was virtually equal. The current process is proposed as a sustainable and effective methodology for the generation of polyphenol-enriched extracts from S. fruticosa, which could be used as effective food antioxidants/antimicrobials and/or cosmetic constituents.