Miracle-dz/UniFAR-FTUs huggingface dataset:
Ultrasound‐facilitated central venous cannulation

ObjectiveTo compare the conventional method for cannulation of the internal jugular vein with the ultrasound-aided technique. DesignProspective, randomized trial. SettingMedical and surgical patients requiring central cannulation in a university hospital. PatientsConsecutive medical and surgical patients in whom central venous cannulation was indicated. InterventionsCannulation of the internal jugular vein was performed by one anesthesiologist. During the first 6 months, the ultrasound-aided technique (n = 29) was used, and during the second 6 months, the conventional technique (n = 27) was applied. Measurements and Main ResultsThe venous lumen was reached with fewer punctures (1.2 ± 0.5 vs. 3.3 ± 3.0 punctures per patient) and the cannulation time was shorter (35 ± 19 vs. 198 ± 211 sees) while using the ultrasound-aided technique. The ultrasound-aided method showed that the large-bore (diameter >2.0 mm) needles invariably perforated the medial wall of the internal jugular vein, increasing the risk of perforating the adjacent carotid artery. ConclusionsUltrasound guidance reduces both the duration of time and the number of punctures required to cannulate the internal jugular vein. The Seldinger technique appears safer for catheterization of the internal jugular vein.
Statistical behavior in deterministic quantum systems with few degrees of freedom.

Numerical studies of the dynamics of finite quantum spin chains are presented which show that quantum systems with few degrees of freedom (N = 7) can be described by equilibrium statistical mechanics. The success of the statistical description is seen to depend on the interplay between the initial state, the observable, and the Hamiltonian. This work clarifies the impact of integrability and conservation laws on statistical behavior. The relation to quantum chaos is also discussed.
Eco-physiological studies of an intertidal crustacean, Pollicipes polymerus (Cirripedia, Lepadomorpha): aquatic and aerial respiration.

1. Physiological responses to environmental stresses of the intertidal cirriped Pollicipes polymerus have been studied by combined field and laboratory experiments. 2. The body temperature of air-exposed animals is always lower than expected from the heat load. Evaporation from the peduncle is responsible for the heat loss. 3. The rate of water loss by evaporation from the peduncle cuticle is 1.5 µl/cm 2 h mmHg both at 21 and 27 °C. The transpiration is proportional to the saturation deficit of the air. The water loss from the capitulum is negligible in comparison to that from the peduncle. 4. The haemolymph osmolality of animals in the field increases during exposure to sunshine and decreases during exposure to rain. The increase in haemolymph osmolality during desiccation is equal to that calculated from the decrease in body water. The water loss during air exposure is adequately replaced during submersion, probably by osmosis. 5. Pollicipes is an osmoconformer but is 5-20 m-osmoles hyperosmotic. It tolerates sea-water dilutions down to about 50%. The hyperosmolality seems to be balanced by a high internal hydrostatic pressure. 6. An excretory activity is observed. The excretion is isosmotic to the haemolymph and is possibly an ultrafiltrate of the latter. 7. The muscle cells show volume regulation, but free amino acids seem to be unimportant in regulation of intracellular osmolality. The concentration of ninhydrinpositive substances in the muscle tissue is about 200 mM for animals in full strength sea water.
Faddish Stuff: Epigenetics and the Inheritance of Acquired Characteristics

“Epigenetic changes are short-term heritable alterations in gene expression that are not due to mutations . Like variations in a letter’s font . we are still at sea as to how it all works . short term bar codes on our cells so that they remember where they’ve been and where they should be going . if they get lost we call it cancer, etc. . since epigenetic changes can be induced by diet, etc . ”
Different roles for Gi and Go proteins in modulation of adenylyl cyclase type‐2 activity

The effect of Gi/o protein‐coupled receptors on adenylyl cyclase type 2 (AC2) has been studied in Sf9 insect cells. Stimulation of cells expressing AC2 with the phorbol ester 12‐O‐tetradecanoyl phorbol‐13‐acetate (TPA) led to a twofold stimulation of cAMP synthesis that could be blocked with the protein kinase C inhibitor GF109203X. Activation of a coexpressed α2A‐adrenoceptor or muscarinic M4 receptor inhibited the stimulation by TPA almost completely in a pertussis toxin‐sensitive manner. Activation of Gs proteins switched the response of the α2A‐adrenoceptor to potentiation of prestimulated AC2 activity. The potentiation, but not the inhibition, could be blocked by a Gβγ scavenger. A novel methodological approach, whereby signalling through endogenous G proteins was ablated, was used to assess specific G protein species in the signal pathway. Expression of Go proteins (αo1 + β1γ2) restored both the inhibition and the potentiation, whereas expression of Gi proteins (αi1 + β1γ2) resulted in a potentiation of both the TPA‐ and the Gs‐stimulated AC2 activity. The data presented supports the view of AC2 as a molecular switch and implicates this isoform as a target for Go protein‐linked signalling.
Inflammatory Bowel Disease: Anatomical and Histopathological Study

Worldwide, the frequency of chronic inflammatory bowel disease (CIBD), including ulcerative colitis (UC) and Crohn's disease (CD) increased rapidly through the last century making their histopathological diagnosis daily task for all pathologists. The accurate histopathological diagnosis of UC and CD requires an intimate correlations between the clinical, laboratory and endoscopic findings in conjunction to the suitable obtained biopsy material, as there are several diagnostic confusions between CIBD and non CIBD forms. The aim of this study was to focus and analyze certain practically selected histopathological features for the diagnosis of UC and CD including crypt architectural abnormalities, inflammation and an associated dysplasia or adenocarcinoma. This present study was performed on 100 specimens of tissue samples taken from small and large bowel including 3 ileocecal resections which were done for suspected an IBD. All the tissue samples received fixed in 10% neutral buffered formalin fixative solution, and paraffin-embedded tissue sections were prepared and examined microscopically for the histopathological features which distinguishing CIBD from non CIBD colitis. This study revealed 95 cases CIBD, among them 55 cases CD and 40 cases were UC, whereas the remaining 5 cases were non CIBD colitis. This study concluded that the diagnosis of IBD needs interdepartmental correlations to avoid under- or over-diagnosis. As well as the accurate discrimination of CIBD from non CIBD forms, differentiate UC from CD, and to identify any dysplastic lesions which is the backbone for therapeutic and prognostic strategies.
Fit of implant-supported fixed prostheses fabricated on master casts made from a dental stone and a dental plaster.

STATEMENT OF PROBLEM The impression and cast on which an implant-supported fixed prosthesis is fabricated must accurately reproduce the intraoral relations. PURPOSE The fit of fixed prostheses fabricated on master casts poured in a conventional die stone and in an ultra-low-expansion plaster was investigated in vitro. MATERIAL AND METHODS An impression was made of patient replicas with inter-implant abutment distances of 50 and 35 mm. Ten master casts were poured in a conventional die stone (Velmix, Kerr) and 10 in an ultra-low-expansion plaster (Gnathostone, Zeus). A simulated plaster fixed prosthesis was fabricated on each master cast and then returned in a random order to the appropriate patient replica. The fixed prostheses were screwed into place on one abutment with a torque of 10 Ncm. Vertical discrepancies were measured at the other abutment by an operator blinded to the cast on which the fixed prosthesis was fabricated. A 2-way analysis of variance was performed for distance and materials, and significant differences were identified with regression analysis. RESULTS For the 50-mm inter-abutment distance, die stone master casts produced a mean vertical discrepancy of 80 microm (SD 32.50 microm). Plaster master casts produced a mean vertical discrepancy of 42.8 microm (SD 12.17 microm). The means were significantly different (P=.01). For the 35-mm inter-abutment distance, the mean vertical discrepancy produced from the die stone and plaster master casts was 84.33 microm (SD 49.9 microm) and 0 microm (SD 0), respectively. The means were significantly different (P<.001). A significant difference was found between the mean vertical seating discrepancies of fixed prostheses produced from plaster casts with inter-abutment differences of 50 mm and plaster casts with inter-abutment distances of 35 mm (P=.003). No significant differences were found between mean vertical seating discrepancies for fixed prostheses fabricated on die stone casts. CONCLUSION In this in vitro study, master casts poured in an ultra-low-expansion plaster limited to a maximum inter-abutment dimension of 35 mm were more accurate than casts with 50-mm inter-abutment spans or those poured in a conventional die stone.
Skill ontology-based semantic model and its matching algorithm

Ontology application for employment or HR management is becoming an increasingly important task with the development of semantic Web technologies. With the expanding scale of online-recruitment, such failures as low search efficiency, precision ratio, and recall ratio emerge and become worse. According to the actual state, we propose an intelligent recruitment platform with a skill ontology-based semantic model and its matching algorithm, by which recruitment Web sites can automatically find the most appropriate job-seekers for a certain job post and positions for a job-seeker. This framework of semantic matching can also be applied to some other fields such as computer aided industry design and manufacturing information engineering
The epidemiology of narcolepsy in Olmsted County, Minnesota: a population-based study.

STUDY OBJECTIVES To determine the age- and sex-specific incidence rates and prevalence of narcolepsy in a United States community. DESIGN The records-linkage system of the Rochester Epidemiology Project was utilized to ascertain all patients with narcolepsy seen in Olmsted County, Minnesota between 1960 and 1989. Age- and sex-specific incidence rates were calculated, using census data. Prevalence of narcolepsy on January 1,1985 was calculated. SETTING N/A. PATIENTS OR PARTICIPANTS Community patients diagnosed with narcolepsy by a validated set of diagnostic criteria. INTERVENTIONS N/A. MEASUREMENTS AND RESULTS The incidence rate per 100,000 persons per year was 1.37 (1.72 for men and 1.05 for women). The incidence rate was highest in the 2nd decade, followed in descending order by the 3rd, 4th and 1st decades. The prevalence on January 1, 1985 was 56.3 per 100,000 persons. Approximately 36% of prevalence cases did not have cataplexy. CONCLUSIONS Narcolepsy is not a rare disorder. It appears to be commoner in men. It originates most commonly in the 2nd decade. Narcolepsy without cataplexy is an important subgroup, warranting further study.
Chlamydia pneumoniae Infections in Patients with Community-acquired Pneumonia in Slovenia

It is well known that Chlamydia pneumoniae is an important respiratory pathogen. In this study, the prevalence of specific antibodies to C. pneumoniae in hospitalized patients with community-acquired pneumonia (943 adult females, 990 adult males and 185 children) was evaluated over a period of 7 y (1993-99). Two serum samples were obtained from all of the patients: 1 on admission and the other 3 weeks later. The specimens were tested for C. pneumoniae IgG, IgM and IgA antibodies by means of a microimmunofluorescence test. Acute infection with C. pneumoniae was determined in 9.4% of females and 13.1% of males. In children and adolescent patients, the microimmunofluorescence test showed recent infection in 8.6% of cases, with the highest prevalence occurring in the 11-15 y age group. The highest prevalence of C. pneumoniae pneumonia was found in 1995 and 1999: 15.4% and 13.6% respectively. The results obtained showed that C. pneumoniae is persistently present in the population of Slovenia.
Use of assessment to reinforce patient safety as a habit

The US spends far more than any other nation on health care. Physicians undergo lengthy and comprehensive training that is carefully scrutinized, and are held to high standards in national examinations. At best the care delivered matches or exceeds that in any other country. And yet, often simple preventable medical errors occur at alarming and unacceptable rates. The public, corporate consumers of health care, large payors and malpractice insurance carriers are all becoming impatient with the pace of improvement. The medical profession recognizes that dealing with this problem is an urgent priority and is grappling to find the best approaches. This paper focuses on the constructive use of assessment to embed a pervasive and proactive culture of patient safety into practice, starting with the trainee and extending out into the practice years. This strategy is based on the adage that “assessment drives curriculum” and proposes a series of new assessment tools to be added to all phases of the training-practice continuum.
Trends in Substance Use among US Military Personnel: The Impact of Changing Demographic Composition

This paper examines the impact of the military population's changing demographic composition on observed changes in substance use by military personnel. Cross-sectional data are drawn from the six Department of Defense Worldwide Surveys of Substance Abuse and Health Behaviors Among Military Personnel conducted in 1980, 1982. 1985. 1988. 1992. and 1995. Using the method of direct standardization to adjust for changes in demographic composition, trends in substance use are examined. Changes in heavy alcohol use were more affected by demographic changes in the military population than were changes in illicit drug use or cigarette use. Findings indicate that changes in demographic composition may need to be controlled when assessing trends from cross-sectional surveys. [Translations are provided in the International Abstracts Section of this issue. ]
Tracking maneuvering targets with multiple biased sensors

When tracking maneuvering targets with multiple sensors, the communication of measurements between the sensors or central-level tracker provides the best responsiveness to target maneuvers. However, when sensors are biased and the biases are not statistically insignificant, the maneuver detection and response in the central-level tracker is degraded. Due to the Markov modeling of the maneuver process in interacting multiple model (IMM) estimator, this degradation of the central-level tracking is acute. In this paper, the challenge of using an IMM estimator for central-level tracking of maneuvering targets with biased sensors is illustrated. In order to reduce the effects of sensor biases on the central-level tracks, the mode likelihoods are evaluated at the sensor and communicated to the central-level tracker along with the measurements. The benefits of using sensor-level mode likelihood in the central-level tracker is demonstrated via Monte Carlo simulations.
Dominant marine bacterioplankton species found among colony-forming bacteria

The density of specific aquatic bacteria was determined by use of whole-genome DNA hybridization towards community DNA. From a coastal marine environment (northern Baltic Sea), 48 specific bacteria were isolated on solid media over a 1-year period. Based on the presented hybridization protocol, the total density of the isolates ranged between 7 and 69% of the bacteria determined by acridine orange direct counts. When compared to the number of nucleoid-containing cells, the range increased to 29 to 111%. Thus, our results showed that bacteria able to form colonies on solid media accounted for a large fraction of the bacterioplankton. There were significant changes in the density of the different bacteria over the year, suggesting that bacterioplankton exhibit a seasonal succession analogous to phytoplankton. The bacteria studied were of diverse phylogenetic origin, being distributed among the alpha, beta, and gamma subdivisions of the class Proteobacteria and the cytophaga-flexibacter group. Partial 16S rRNA gene sequence analysis of 29 Baltic Sea isolates as well as of 30 Southern California Bight isolates showed that a majority of the isolates had low similarity (0.85 to 0.95) to reported sequence data. This indicated that the diversity of marine bacteria able to grow on solid media is largely unexplored.
Expression and function of erythropoietin receptors in tumors

Safety concerns surrounding the use of recombinant human erythropoietin (Epo) to treat anemia in cancer patients were raised after 2 recent clinical studies reported a worse survival outcome in patients who received epoetin α or epoetin β compared with patients who received placebo. Although those findings contrasted with previous clinical studies, which demonstrated no difference in survival for cancer patients who received erythropoiesis‐stimulating agents (ESAs), some investigators have suggested a potential role for ESAs in promoting tumor growth through 1) stimulation of Epo receptors (EpoR) expressed in tumors, 2) stimulation and formation of tumor vessels, and/or 3) enhanced tumor oxygenation. The first and second hypotheses appeared to be supported by some EpoR expression and ESA in vitro studies. However, these conclusions have been challenged because of poor specificity of EpoR‐detection methodologies, conflicting data from different groups, and the lack of correlation between in vitro data and in vivo findings in animal tumor models. For this report, the authors reviewed the biology of EpoR in erythropoiesis and compared and contrasted the reported findings on the role of ESAs and EpoR in tumors. Cancer 2007. © 2007 American Cancer Society.
Patients with Recurrent Renal Stones Have a Physico-Chemically Altered Urinary Tamm-Horsfall Glycoprotein Profile

We describe an immunoblotting method for examining the electrophoretic properties of urinary Tamm-Horsfall protein. Using this method we tested frozen urine samples from a group of 37 thoroughly investigated recurrent idiopathic renal calcium stone formers and compared this with fresh urine from 19 non-stone forming laboratory staff. We found that there was a statistically significant different pattern of Tamm-Horsfall protein bands in the two sets of urines, with stone formers tending to have two bands and non-stone formers tending to have three bands. This could have been due to storage artefact and therefore a further group of 13 fresh urines from unselected renal stone formers was tested. A smaller proportion of these cases showed the two-band pattern, possibly because not all of this group were idiopathic calcium stone formers. This suggests that but does not prove that there is no significant storage artefact and that there may be an in vivo effect causing stone formation.
A New Algorithm for Uncertain Problem of WEB Page Classification

For solving the uncertain problem in the process of WEB page classification, a general fusion classification model and algorithm are proposed, which based on model theory of information fusion. In the model, the hidden classification information is extracted from the WEB page ， pre-processed firstly, then the processed data are input into the fusion mode, which deals with the different data with fusion algorithm, then the final classification results are concluded. An improved Bayesian network is proposed, which can not only solve the uncertain problem during the WEB page classification, but also can reduce the time complexity of the inference. The WEB data of NSTL are adopted in the experiment. The experiment proves the fusion model and fusion algorithm can solve the uncertain problem effectively
The influence of magnetic properties of permanent magnet on the performance of IPMSM for automotive application

High power density is required for motors intended for automotive applications. Therefore, interior permanent magnet synchronous motors (IPMSMs) are commonly used in hybrid electric vehicles and electric vehicles. It is known that the characteristics of the magnetic materials are a significant factor with respect to the performance of the IPMSM, and the magnet is particularly important. In addition, currently, the high-performance magnets that have a high residual magnetic flux density are being developed, and technics for applying these magnets to motors are required. In this paper, three motors having different magnets with different residual magnetic flux densities are investigated for use in automotive applications. As a result, by using a strong magnet, the total torque and output power are increased, and the high-efficiency operating region is widened and shifted to the low-speed, high-torque range. Moreover, the maximum efficiencies at frequently used operating points are compared. In the city-driving, the efficiency is approximately the same. However, the efficiency in highway driving decreases when the strong magnet is used.
Pathological aspects of breast cancer in Indonesian females, applying a modified WHO classification. A joint study between Indonesia and Japan

From the pathological aspect, we analyzed again the histological variants of breast cancer and compare them with cases from Japan. We usecl the classification recommended by the Japanese Breast Cancer Society, which divided the invasive cluctaL carcinoma of NOS (no otherwise specified) of the WHO clnssification into 3 subtypes, namely papiLlàtubulaa solid-tubular and scirrhous carcinoma. We had 515 cases from Inclonesia (lst batch and 2"t batch) treated at the Dr Cipto Mangwtkusumo National Central General Hospital (RSCM) ani 445 cases from Japut, treated at the Cancer Institute Hospital (CIH), The RSCM cases had 0.97Vo noninvasive carcinoma, 89.I4Vo invasive ductal carcinoma antl 9.50Vo of the specialtypes. The CIH cases had 7.4Vo noninvasive carcinoma, B0.4Vo invasive ductal carcinoma anl I L3Vo of the speciaL types. The incidence of noninvasive ductal carcinoma was lower at RSCM, with a 6.43Vo dffirence. Among the subtypes of invasive ductal carcinoma, the scirhous carcinoma was the most common in both groups (RSCM and CIH), with an incirlence of 50.49Vo (RSCM) and 43.67o (CIH). The least common at RSCM was the paPilLotubular type, while at the CIH it was the solicl-tubular type. Among the special types, only 5 variants were encountered at RSCM and 7 at CIH. The incidences of mucinous carcinoma and int,asiye Iobular carcinomawere lower at RSCM, while the medullary carcinoma was higher. The incidence of Paget's disease was also lower at RSCM.