Miracle-dz/UniFAR-FTUs huggingface dataset:
Use of Topic Modelling for Improvement of Quality in the Task of Semantic Search of Educational Courses

— This paper proposes an approach, improving the quality of the original educational course programmes semantic search algorithm, based on vector representations, produced by distributional semantic. The proposed approach works by providing an expert with interpretable topic filtering of courses in search results. Application of probabilistic topic modeling based on additive regularization ensures the interpretability of vector components in representations of texts, allowing the expert, in the process of exploratory search, to narrow down the set of relevant documents found previously by using the vector model. In our experiments, we study the applied task of educational course search, using current requirements of the labor market (requirements described in professional standards serve as search queries). The implementation of topic filtering is based on the open-source library BigARTM. We investigate the influence of hyperparameters and the choice of regularizers in the construction of a topic model on the improvement of quality of educational course semantic search using various vector models: word2vec, fasttext, TF-IDF are investigated.
Statistical structure of self-sustaining attached eddies in turbulent channel flow

Abstract The linear growth of the spanwise correlation length scale with the distance from the wall in the logarithmic region of wall-bounded turbulent flows has been understood as a reflection of Townsend’s attached eddies. Based on this observation, in the present study, we perform a numerical experiment, which simulates energy-containing motions only at a given spanwise length scale in the logarithmic region, using their self-sustaining nature found recently. The self-sustaining energy-containing motions at each of the spanwise length scales are found to be self-similar with respect to the given spanwise length. Furthermore, their statistical structures are consistent with those of the attached eddies in the original theory, providing direct evidence on the existence of Townsend’s attached eddies. It is shown that a single self-sustaining attached eddy is composed of two distinct elements, one of which is a long streaky motion reaching the near-wall region, and the other is a relatively short vortical structure carrying all the velocity components. For the given spanwise length ${\it\lambda}_{z}$ between ${\it\lambda}_{z}^{+}=100$ and ${\it\lambda}_{z}\simeq 1.5h$ , where $h$ is half the height of the channel, the former is found to be self-similar along $y\simeq 0.1{\it\lambda}_{z}$ and ${\it\lambda}_{x}\simeq 10{\it\lambda}_{z}$ , while the latter is self-similar along $y\simeq 0.5{\it\lambda}_{z}\sim 0.7{\it\lambda}_{z}$ and ${\it\lambda}_{x}\simeq 2{\it\lambda}_{z}\sim 3{\it\lambda}_{z}$ where $y$ is the wall-normal direction. The scaling suggests that the smallest attached eddy would be a near-wall coherent motion in the form of a streak and quasi-streamwise vortices aligned to that, whereas the largest one would be an outer motion with a very-large-scale motion (VLSM) and large-scale motions (LSMs) aligned to that. The attached eddies in between, the size of which is proportional to their distance from the wall, contribute to the logarithmic region and fill the space caused by the length scale separation. The scaling is also found to yield behaviour consistent with the emergence of $k_{x}^{-1}$ spectra in a number of previous studies. Finally, a further discussion is provided, in particular on Townsend’s inactive motion and several recent theoretical findings.
Severe Modifications of Biological Markers in Late Neonatal Sepsis in a Very Low Birth Weight Due to Candida lusitaniae

Neonatal sepsis is a major cause of neonatal mortality and morbidity in preterm, very low birth weight infants. Coagulase-negative staphylococcus and Candida spp. are among the most common causes of single infections and coinfections in neonates. Candida lusitaniae is rarely reported as an opportunistic pathogen in very low birth weight neonates. Early diagnosis and appropriate antifungal therapy can prevent morbidity and mortality in preterms especially in coinfections. Necrotizing enterocolitis is one of the most catastrophic gastrointestinal emergencies in premature infants in the intensive care neonatal unit, especially in preterm infants. Currently, the pathogenesis of necrotizing enterocolitis is believed to have multifactorial causes. We present the case of a very low birth weight preterm who developed necrotizing enterocolitis and sepsis caused by a coinfection of Coagulase-negative Staphylococcus and Candida lusitaniae.
AB020. PS01.02. Identification of potential biomarkers in thymectomy specimen from myasthenia gravis patients in the MGTX-trial

Background: The thymectomy trial in non-thymomatous myasthenia gravis (MG) patients receiving prednisone therapy (MGTX) showed that transsternal thymectomy combined with prednisone was more efficient than prednisone alone in terms of improving muscle weakness and quality of life, and reducing total prednisone dose of MG patients. The resulting surgical specimen underwent a rigid work-up, which allows us to look for correlations between histomorphological features and clinical parameters obtained for the study. The aim was to identify potential prognostic and predictive tissue biomarkers. Methods: A total of 126 non-thymomatous MG patients underwent randomization to the prednisone-only or the thymectomy group. Fifty-six patients agreed to have their thymectomy specimens evaluated by reference pathologists. One patient was excluded because of detection of a B2 thymoma. For the other 55 thymectomy specimens all obtained tissue blocks (11±5 blocks per specimen) underwent a pre-defined standard diagnostic protocol: first, all sections were hematoxylin-eosin (HE)-stained and evaluated for e.g., percentage of fat tissue on the slide; percentage of intra-thymic fat tissue; grading of cortical atrophy; grading of follicular hypertrophy; number of follicles, and percentage of cortical and medullary area. Second, slides containing thymic parenchyma were immunohisto-chemically stained for CD23 (expressed by follicular dendritic cells) using a routine immunoperoxidase technique. Then, numbers and morphology of lymphoid follicles were “manually” assessed on digitalized sections. Results: So far the above work-up led to 17 histological variables of different measurement scales per slide (e.g., percentage of fat tissue as interval scaled data (0–100%); grading of thymic follicular hyperplasia (grades 0–4) as ordinal scaled data. Comparing the patient data to data from a historical, non-inflammatory collective showed a trend to hypertrophy of thymic tissue in the MGTX-collective. Nonphysiological lymphofollicular hyperplasia (grades 2–4), i.e., the hallmark of thymuses of prednisone-naïve early onset MG patients was observed in only 27% of cases, reflecting the impact of prednisone on LFH. Conclusions: Most “traditional” histological features (e.g., grade of lymphofollicular hyperplasia) showed no significant correlation to clinical parameters. However, we shall present and discuss more sophisticated morpho-metry-based features that hold promise for predictive significance in terms of MG outcome and recommendations for optimal and economical sampling of thymectomy specimens.
Testing user-tailored e-health services in practice: results and lessons learned

This paper evaluates a patient self-management system that provides user-tailored e-health services. The system provides a set of health related services (e.g. vital sign monitoring, medication support) to elderly people. These services stem from different vendors and technological origins, yet they can be integrated and tailored to individual care needs. This paper describes the results of an evaluation of the system in a nursing home. Eight clients and 4 nurses of a nursing home tested the system in a pilot study between May and November, 2012. Results show that is possible to create a platform that enables patient-specific care. The platform provides useful applications in care. These applications can save time for caregivers, and increase self-management in patients. However, it requires investment in the learning process. The work shows that this platform successfully integrates and tailors heterogeneous sensors, actuators and services from different vendors and technological origins. Adequate personalization of selected e-health services can save time, increase health situation awareness and further patient empowerment.
The Utilization of ArbuscularMycorrhizal Fungi For Planting Agarwood (Aquilariaspp) Seedling In Open Land

Agarwood is a type of semitoleran plant, so that for planting the seedlings should be grown under the shade. For planting in open land, it requires treatment in which one of them is using seedlings inoculated with arbuscularmycorrhizal fungi. The Aim of the research were: (1) to obtain information on agarwood growth that has been inoculated with fungi mycorrhizalarbuscular when planted in the open land, and (2) ability to grow between agarwood seedlings inoculated mycorrhizal that was planted in the shade and in the open area. Split Plot randomized block design was applied with treatments : the first plot consisting of plant had been inoculated with mycorrhizae and without mycorrhizal inoculation, and the sub plot was the types of shading that consists of : open land, paranet 60 % intensity and natural vegetation. To reduce variabilty of site topographical differences were separated as bloks. Variables measured were :plant height (cm), stem diameter (mm), number of leaves and survival percentage of plant. The results show that the height and diameter growth of seedlings innoculated with mycorrhizae were higher than non innoculated. The seedlings innoculated with mycorrhizal fungi were planted in the paranet shading grew better and significantly different compared to the vegetation shading. Seedlings innoculatedmycorrhizal that were planted in open land grew better and significantly different compared to vegetation shading. This study results indicate that planting agarwood in the open land can be done using seedlings inoculated arbuscularmycorrhizal fungi.
PENGARUH GREEN PERCEIVED VALUE DAN GREEN BRAND IMAGE MELALUI GREEN SATISFACTION DAN GREEN TRUST TERHADAP GREEN BRAND EQUITY PADA PARIWISATA KREATIF DI JAWA BARAT

Industri pariwisata di Jawa Barat perlu mengembangkan model Green Marketing pada pariwisata kreatif karena pariwisata kreatif berpotensi besar dalam memberikan kontribusi ekonomi yang signifikan, menciptakan iklim bisnis yang positif, serta membangun citra dan identitas bangsa. Tujuan penelitian ini adalah untuk menganalisis pengaruh Green Brand Image dan Green Perceived Value melalui Green Brand Satisfaction dan Green Trust terhadap Green Brand Equity untuk diterapkan di bidang pariwisata kreatif di Jawa Barat. Metode penelitian yang digunakan adalah metode kuantitatif dengan survey sebagai instrumen utama. Survey dilakukan terhadap wisatawan di lima lokasi pariwisata kreatif di Jawa Barat, dengan sampel sebanyak 250 responden. Data dianalisis menggunakan Partial Least Square (PLS). Hasil penelitian memperlihatkan bahwa Green Perceived Value dan Green Brand Image berpengaruh signifikan terhadap Green Brand Equity melalui Green Brand Satisfaction dan Green Trust baik secara parsial dan simultan, dengan pengaruh terbesar yaitu Green Brand Image terhadap Green Satisfaction dan pengaruh terendah yaitu Green Satisfaction terhadap Green Brand Equity.
CORRELATION BETWEEN AERATION AND ERGOSTEROL PRODUCTION BY YEASTS

The present study represents an extension of ergosterol production by Saccharomyces cerevisiae fermentation processes using oxygen-vector by establishing the influence of the analyzed main factors, such as aeration efficiency and hydrocarbon concentration. The study has been developed for batch and fed-batch fermentation systems and has been focused on the variation of ergosterol content inside the yeast cells during the fermentation cycle in correlation with hydrocarbon volumetric fraction, COV, glucose concentration, CG, and air superficial velocity, vS. Moreover, the variation of ergosterol content has been discussed in relation to the oxygen mass transfer coefficient, kLa. The experimental results obtained in both fermentation systems were quantified in two mathematical correlations describing the influences of the mentioned main parameters on ergosterol concentration, CE. These two equations have the general expression, with the experiments, the average deviations being . 5.94% for batch fermentation and . 4.18% for fed-batchfermentation.
Adaptive Tracking Control of Cooperative Robot Manipulators With Markovian Switched Couplings

Many cooperative robotic systems have not only modeling heterogeneity and uncertainty but also switched couplings, causing control difficulties. Here, we develop a neural network adaptive control framework for cooperative robot manipulators with unknown Euler–Lagrange dynamics and Markovian switched couplings. Second-order Markovian switching networks are used for modeling such cooperative robotic systems, which admit a hybrid neural network control with a desired tracking performance. The hybrid neural network control scheme contains a distributed adaptive controller and a hybrid adaptation law, enabling learning in the closed-loop system. The position and velocity tracking errors are shown to be practically uniformly exponentially stable in the mean-square sense, respectively, guaranteeing the second-order practical tracking. The results also suggest that the neural weight evolves with practical convergence to the ideal, showing the effect of network structure on the adaptation capacity.
Resistance to Narrowband Ultraviolet B Therapy Over Varicose Veins in Two Cases of Generalized Vitiligo

Vitiligo is a difficult-to-control disease with a devastating impact in the lives of many patients. An association has been shown between the Koebner phenomenon and the occurrence of skin depigmentation in vitiligo. However, the medical literature contains very little information regarding the relationship between varicose veins, a commoncomorbidity formanypatients, and vitiligo skin lesions. We present two cases of generalized vitiligo in which patients experienced delayed or absent repigmentationexclusively over varicoseveinsafter narrowband ultraviolet B therapy, despite repigmentation over the rest of the body. In one case, repigmentation occurred after varicose vein treatment. These patients highlight potential andpreviously unexplored interactions between varicose veins and response to vitiligo phototherapy. The impact of varicose veins on vitiligo treatment may inform future research ideas into the pathogenesis of this skin disease. Furthermore, these cases suggest a possible mechanism of improving local treatment response in vitiligo by addressing underlying varicose veins.
Seroprevalence of New Castle Disease Virus in Local Chickens from Sokoto, Nigeria

Newcastle disease constitutes a major constraint to the rural poultry production system in Nigeria. This study was carried out to investigate the seroprevalence of Newcastle disease virus (NDV) in local chickens from Sokoto live bird market, Sokoto, Nigeria, through antibody detection using Competitive Enzyme Linked Immunosorbent Assay (cELISA). An overall seroprevalence rate of 14.72% (34/231) was recorded in this study. Comparison was made between the seroprevalence in sexes and between ages (p>0.05). Female birds had higher prevalence (15.32%) compared to males (14.02%). Higher prevalence was recorded in young chicks (18.75%) and least in adults (13.66%) p >0.05. The study indicated that Newcastle disease is present amongst the population, and sex and age of the birds had no significant influence on the seroprevalence of NDV in the study area. Hence, there should be an improvement in vaccination campaign against Newcastle disease in local chickens.
Sténoses athéromateuses des artères rénales : intérêt de la revascularisation percutanée dans la maladie rénovasculaire sévère

La maladie atheromateuse renovasculaire est responsable d’une morbi-mortalite elevee. Plusieurs essais randomises ont conclu a l’absence de benefice de la revascularisation percutanee en comparaison au traitement medical optimise. Cependant ces etudes ne prenaient pas en compte les presentations cliniques a haut-risque regroupant hypertension arterielle (HTA) resistante, œdeme aigu pulmonaire (OAP) flash ou insuffisance renale rapidement progressive. Ainsi, nous avons evalue l’interet de l’angioplastie plus particulierement dans cette population en contexte de stenoses bilaterales des arteres renales severes. Objectifs Nous avons realise une etude observationnelle retrospective au CHU de Rouen sur 83 patients, entre le 01/01/1996 et le 31/12/2017 inclus, atteints de stenose atheromateuse des arteres renales (SAAR) ≥ 50% bilaterales ou unilaterales sur rein unique (40% des SAAR ≥ 80%). L’objectif principal de l’etude etait d’analyser a la fois pour les presentations a haut-risque (n=53, 64%) regroupant HTA resistantes (n=29), OAP flashs (n=11), HTA resistantes avec insuffisance renale aigue (IRA) associee (n=9) et IRA isolee (n=4) ; et a bas-risque (n=30, 36%), l’impact de l’angioplastie sur la mortalite, l’evolution vers l’insuffisance renale chronique (IRC) terminale et la survenue d’evenements cardiovasculaires (ECV) en comparaison au traitement medical. Secondairement, nous avons evalue l’interet de l’angioplastie sur le profil tensionnel et la fonction renale. Resultats Au total 54 patients ont ete revascularises dont 66% dans le groupe haut-risque. Au cours d’un suivi median de 52 mois, 60% des patients haut-risque sont decedes, 25% ont evolue vers l’IRC terminale et enfin plus de 40% ont subi au moins un ECV. Nous mettons en evidence, dans ce groupe, un benefice de l’angioplastie a la fois sur la mortalite et la survie renale en cas de SAAR ≥ 80% (respectivement p=0,01 et p=0,02). Nous montrons egalement un benefice de l’angioplastie sur l’amelioration de la PA systolique (groupe haut-risque) a 6 et 12 mois avec respectivement une baisse de 9 mmHg (p=0,01) et 10 mmHg (p=0,005). L’interpretation de nos resultats est limitee par l’aspect retrospectif de l’etude et ses biais, le faible effectif et le manque de puissance de notre analyse statistique. Conclusion Cette etude tend a montrer un benefice superieur de l’angioplastie comparativement au traitement medical, dans la prise en charge des patients a haut-risque en contexte de MARV severe, en coherence avec les publications recentes.
Dépistage du cancer de la prostate : perception et facteurs d'adhésion chez les hommes à risque familial

L'objectif de ce travail etait de decrire la perception et les facteurs d'adhesion des hommes apparentes au premier degre a des patients atteints d'un cancer de la prostate au depistage du cancer de la prostate.Deux cohortes de sujets ont ete etudiees. - Une cohorte de sujets americains (Universite de Californie LosAngeles) comprenait des apparentes au premier degre d'hommes atteints d'un cancer de la prostate identifies a partir d'un echantillon de patients. - Une cohorte de sujets francais comprenait des apparentes au premier degre d'hommes atteints d'un cancer de la prostate traites dans trois CHU francais a qui il a ete propose un depistagegratuit par dosage du Prostate Specifie Antigen (PSA). Parmi la premiere cohorte, 139 hommes ont participe (âge 53 ± 9 ans), 92% etaient caucasiens et 29% avaient plus d'un apparente atteint d'un cancer de la prostate. La connaissance du cancer de la prostate etait bonne. Parmi ceux qui avaient une connaissance correcte du risque familial de developper un cancer de la prostate, seulement 62% croyaient etre eux-memes plus a risque que l'Americain sans risque familial. 62% des hommes ont eu un dosage du PSA et un toucher rectal dans les deux ans qui precedaient. Les hommes âges de plus de 50 ans, qui avaient discute avec leur medecin de famille du depistage du cancer de la prostate, qui avaient une bonne connaissance concernant la frequence recommandee du depistage du cancer de la prostate et les hommes sans comorbidite ont eu un depistage plus frequemment que les autres.Concernant la deuxieme cohorte, 273 ont eu un dosage du PSA et 220 candidats avec un PSA :s; 4 ng/ml ont retourne les questionnaires complets. 20% ont moderement deteriore leur anxiete et 20% ont deteriore de facon minimale leur qualite de vie durant la procedure de depistage. Les facteurs associes avec une deterioration de la qualite de vie etaient un âge entre 50-60 ans, avoir plus de deux apparentes atteints d'un cancer de la prostate, une personnalite anxieuse, un haut niveau de scolarite et ne pas avoir d'enfants vivants a la maison. Enfin concernant la perception des problemes genetiques, 277 candidats ont rempli le questionnaire et ont eu un dosage du PSA. 64% etaient peu ou pas preoccupes par le probleme de la predisposition genetique tandis que les autres etaient tres ou enormement preoccupes. Les candidats les plus preoccupes etaient ceux avec une anxiete chronique (ou durable, constitutionnelle) elevee, ceux ayant deja eu un depistage et les hommes ayant des fils.98% des hommes exprimerent leur interet vis a vis des tests genetiques.
Primary Care Compact- transferring theoretical knowledge into practice

Introduction As in many medical disciplines all over the world, primary care medicine in Germany is facing a substantial lack of successors. Enhancing the attractiveness of that discipline might be achieved by inspiring learning formats for undergraduate students. Methods A new course combining several approaches to enhance learning outcomes was established and conducted at the University of Münster. Those approaches were tailored to an all new facility constructed to enhance competencybased learning formats called "LIMETTE". Strategies used were adjusted to established undergraduate and postgraduate training models. Results The course "primary care compact" was very well evaluated by the attending students. Especially the transfer of theoretically acquired knowledge into practice was highly appreciated. The elaborated preparation material was acknowledged as being very helpful in repeating and preparing topics of interest for that course, too. Discussion Developing established concepts and combining them into a new course seems to pay off in terms of perceived attractiveness of that course and the conducting discipline. Conclusion Sophisticated learning formats can help to understand and experience some of the core-elements of a discipline and might this way increase the reputation of a discipline and may help to ease successor issues in the future.