Miracle-dz/UniFAR-FTUs huggingface dataset:
Secure Personal Health Records Using Encryption

In the dispersed world, health information is exchanged based on the patients Personal Health Records (PHRs). Due to this reason, the construction and maintenance are focused by data centers, which are used for persons to gain high cost. The cloud providers are used in most of the PHR services to outsource the PHRs, which are stored by third party. The privacy is main anxiety because the PHRs information is shared to third party servers and illegal parties. To avoid this problem and to provide the guarantee security for PHRs, the encryption is applied for all PHRs before it is outsourcing. After encryption is applied still few major issues are present such as, flexible access, scalability in key organizations and well organized user revocation. These are the residual important challenges. In this proposed system, a patient-centric model has been generated with appropriate mechanisms for accessing PHR which are stored in semi confidential servers. Here the Attribute Based Encryption technique is used to encrypt every patients PHR’s. To support on demand, user revocations are also enabled dynamically based on the variations of access policies or file attributes to improve the process. Keywords-cloud computing, personal health records.
Site‐specific anti‐tumor immunity: Differences in DC function, TGF‐β production and numbers of intratumoral Foxp3+ Treg

Gliomas localized within the CNS are generally not rejected by the immune system despite being immunogenic. This failure of the immune system has been associated both with glioma‐derived immunosuppressive molecules and the immune‐privileged state of the CNS. However, the relative contribution of tumor location to the glioma‐mediated immunosuppression, as well as the immune mechanisms involved in the failure of glioma rejection are not fully defined. We report here that syngeneic GL261 gliomas growing either intracranially or subcutaneously in mice are infiltrated by DC and T cells. However, only subcutaneous gliomas elicit an effective anti‐tumor immune response. In contrast to DC infiltrating subcutaneously grown GL261 gliomas, tumor‐infiltrating DC from intracranial gliomas do not activate antigen‐dependent T‐cell proliferation in vitro. In addition, brain‐localized GL261 gliomas are characterized by significantly higher numbers of Foxp3+ Treg and higher levels of TGF‐β1 mRNA and protein expression when compared with GL261 gliomas in the skin. Our data show that gliomas in the CNS, but not in the skin, give rise to TGF‐β production and accumulation of both Treg and functionally impaired DC. Thus, not the tumor itself, but its location dictates the efficiency of the anti‐tumor immune response.
Butyrate from bacterial fermentation of germinated barley foodstuff preserves intestinal barrier function in experimental colitis in the rat model

Background and Aims : The consumption of germinated barley foodstuff (GBF) prevents inflammation and diarrhoea in a colitis model. In this study we investigated the mechanism of the preventative effect of GBF on experimental colitis in rats, in view of production of bacterial butyrate and preservation of intestinal barrier function.
Are rates of ageing determined in utero?

BACKGROUND epidemiological studies have shown that poor early growth is associated with cardiovascular and other degenerative diseases. This has been explained by programming, whereby undernutrition and other influences which restrict early growth permanently change the structure and physiology of the body. The long-term effects of poor early nutrition on ageing have been demonstrated in animals but not studied in man. OBJECTIVES to determine if poor early growth was associated with increased markers of ageing in later life. METHODS we traced 1428 men and women, born in Hertfordshire between 1920 and 1930, for whom records of early weight were available. 824 (58%) were interviewed at home and 717 (50%) attended clinic for eye examination, audiometry, grip strength measurement, skin thickness ultrasound and anthropometry. RESULTS lower weight at 1 year was associated with increased lens opacity score, higher hearing threshold, reduced grip strength and thinner skin. Visual acuity, macular degeneration and intraocular pressure were not related to early growth. CONCLUSIONS the associations between early growth and markers of ageing suggest that in some systems, ageing may be programmed by events in early life. A potential mechanism is the impaired development of repair systems.
Co-Evolution of Human and Machine: Neuroprosthetics in the 21st Century

Throughout the history of mankind, tools have served the role as passive extensions of the body. Recently, the development of neuroprosthesis has changed the scope of how humans interact with tools. Neuroprosthetics enable direct interfacing with the brain and have the great potential for restoring communication and control in disabled individuals. The transformative aspect of direct neural interfaces is that they can be designed as ‘intelligent tools’ that not only carry out intent but also have the capability to assist, evolve, and grow with the user. Unlike other tools, neuroprosthetics exist in a shared space that seamlessly spans the user’s internal representation of the world and the physical environment enabling a much deeper humantool symbiosis. Recent advancements in the engineering of neuroprosthetics are providing a blueprint for how new coadaptive designs change the nature of a user’s ability to accomplish tasks that were not possible using conventional methodologies. This paper analyzes how key advances in science and technology supporting the development of intelligent neuroprosthesis and contrasts them with “lessons learned” from the past 50 years in the IEEE. Keywords-neuroprosthesis; brain-computer symbiosis; cybernetics; brain-machine interface; co-adaptation
Ecologically Sustainable Organizations: An Institutional Approach

Our main objective in this article is to join the growing group of "green" organization theorists by demonstrating the usefulness of institutional theory as an approach to ecologically sustainable organizations. Institutional theory helps to understand how consensus is built around the meaning of sustainability and how concepts or practices associated with sustainability are developed and diffused among organizations. We extend institutional theory by offering hypotheses in four different areas: (a) the incorporation of values into organizational sustainability, (b) the study of institutions as distinct elements within systems, (c) the study of institutions as distinct spheres, and (d) the construction of paradigms that support organizational sustainability. We then offer possible modifications to institutional theory that are suggested by the extension to a new area of study. Among them are the consideration of natural constraints on sense making and paradigm construction, the study of regional networks, and the recognition of the role of individual actors. Finally, we discuss possible avenues for future research by drawing on research that we are currently conducting.
Design of a User Interface for a Transactional Web Site for a Local Government

Online shopping systems should provide price comparison, guarantee of the product quality, comments of other buyers, and so on. Among the salient features of online shopping, this paper emphasizes on visualizing product because most of online shopping systems only provide images of product. This paper introduces a design of an online shopping system that provides high quality videos of products and other salient features as well.
The geometry of a probabilistic consensus of opinion algorithm

We consider the problem of a group of agents whose objective is to asymptotically reach agreement of opinion. The agents exchange information subject to a communication topology modeled by a time varying graph. The agents use a probabilistic algorithm under which at each time instant an agent updates its state by probabilistically choosing from its current state/opinion and the ones of its neighbors. We show that under some minimal assumptions on the communication topology (infinitely often connectivity and bounded intercommunication time between agents), the agents reach agreement with probability one. We show that this algorithm has the same geometric properties as the linear consensus algorithm in R". More specifically, we show that the probabilistic update scheme of an agent is equivalent to choosing a point from the (generalized) convex hull of its current state and the states of its neighbors; convex hull defined on a particular convex metric space where the states of the agents live and for which a detailed description is given.
The Case for FairShares: A new model for social enterprise development and the strengthening of the social and solidarity economy

Imagine a society in which every adult is entitled to co-own the organisations on which they, their family and their community depends… The FairShares Model is an approach to creating networks of solidarity enterprises. Every adult can become a member-owner, whether a founding entrepreneur, supplier, employee, customer, user or social investor. This book clearly sets out why we need FairShares, how to provide FairShares education and the legal templates for a new generation of social enterprises that apply FairShares values and principles.
Estradiol and Testosterone Have Opposite Effects on Microtubule Polymerization

We have reported earlier the purification of tubulin from a plasmalemmal-microsomal fraction derived from rat hippocampus using an estradiol (E2) affinity column and the specific binding of tubulin to both E2 and testosterone (T). To further investigate the effect of E2 and T on the function of this protein, changes in microtubule polymerization as a result of exposure to the steroids were examined in this study, using both pure tubulin and rat hippocampal primary cell cultures. First, pure tubulin was incubated with or without steroids for 30 min on ice followed by polymerization at 37°C. The numbers of microtubules formed were counted from electron microscopic pictures. The results showed that at 30 min of polymerization, 10 nM, 30 nM and 30 µM of E2 inhibited microtubule assembly by –70%, –94%, and –92%, respectively (p < 0.01), while T at the same three concentrations stimulated it by +83%, +66%, and +121%, respectively (p < 0.05). The inhibitory effect of E2 and the stimulatory effect of T were observed at 15, 30 and 60 min of the polymerization process. Next, primary cell cultures from 17-day rat fetus hippocampal tissues were treated with the steroids and polymerized microtubules (Triton X-100 resistant) were examined by immunocytochemistry. The results demonstrated that 60 min of E2 treatment (10 nM) decreased the intensity of the immunolabeling of polymerized microtubules. The effect of T at nM concentration was not significant though it increased the immunolabeling at µM concentration. Of great significance was a remarkable inhibition by T of the well-established depolymerization effect of colchicine in both the pure tubulin assay and the cell culture model, while E2 was not effective. In an effort to pursue the possible mechanism(s) of the effect of E2 and T on microtubule formation, we found that T only inhibited the microtubule depolymerization process without affecting the rate of polymerization. In contrast, E2 modifies only the polymerization process without altering the depolymerization. Overall, these data indicate that E2 and T may be considered as novel regulators of microtubule dynamics and thereby controlling cytoskeleton function in cells.
Sensors in robotic arc welding to support small series production

Purpose – Aims to present general concepts and framework for increasing the flexibility in robotic arc welding with respect to use of sensors and small series production.Design/methodology/approach – Presents a conceptual model with a framework that integrates existing tools and needed developments and research to increase the usefulness of sensors in robotic arc welding. The conceptual model is based on research within the field which covers supporting tools like robot simulation, sensor modelling and handling and optimization issues with respect to the robot task execution. A descriptive structure and concept is outlined to include welding procedure specifications (WPS) as a key module to provide an integrated and holistic control model of the robotic.Findings – Finds that the outlined conceptual model and architecture supports an increased flexibility of sensor controlled robots for arc welding applications. The arguments are specifically made for small series and one‐off production.Research limitation.
Conceptual Framework on Corporate Branding

Corporate branding can be described as the process of creating, nurturing and sustaining a mutually rewarding relationship between a company and its internal and external stakeholders including managers and other employees of the company, customers, investors, suppliers, corporate partners, members of the local community, and special interests like activists. Corporate brand is a product of millions of experiences a company creates-with employees, vendors, investors, reporters, communities, and customers-and the emotional feelings these groups develop as a result. A strong corporate brand creates, manages, and fulfills high expectations among its many audiences. In corporate branding, all the products across the businesses will carry the corporate name. For instance, Sony might be considered the ultimate corporate endorser with its name firmly attached to everything from its DVD to the Play Station. Companies have recognized the power of corporate branding as a business strategy in India. This study explores the insights in to Concepts of Corporate branding with showing light on successful stories of corporate brands in Indian and global context. This study also evaluates the ACID frame work for developing corporate image for marketers.
How to Avoid Compensating CEO for Luck: The Case of Macroeconomic Fluctuations

Incentive effects of performance-based compensation schemes for management may be weakened or biased by macroeconomic influences on remuneration. These influences can be seen as reflecting luck from the CEO’s perspective. In this chapter we present a model for how to avoid compensating CEO for luck by filtering out the macroeconomic influences. In the empirical section we analyze the impact of macroeconomic, industry and firm-specific factors on the compensations (salary, bonus, options, and pensions) of CEOs in 127 Swedish corporations during the period 2001-2007. We find macroeconomic influences on Swedish CEOs’ compensation to be substantial. Distinguishing between favorable and unfavorable macroeconomic developments, we find compensation to be more responsive to favorable than to unfavorable developments in macroeconomic variables.
Impacts of concurrency, iteration, design review, and problem complexity on design project lead time and error generation

A case study of an aircraft engine manufacturer is used to analyze the effects of management levers on the lead time and design errors generated in an iteration-intensive concurrent engineering process. The levers considered are amount of design-space exploration iteration, degree of process concurrency, and timing of design reviews. Simulation is used to show how the ideal combination of these levers can vary with changes in design problem complexity, which can increase, for instance, when novel technology is incorporated in a design. Results confirm that it is important to consider multiple iteration-influencing factors and their interdependencies to understand concurrent processes, because the factors can interact with confounding effects. The article also demonstrates a new approach to derive a system dynamics model from a process task network. The new approach could be applied to analyze other concurrent engineering scenarios.
Contrast-enhanced MR Angiography of the renal arteries: blinded multicenter crossover comparison of gadobenate dimeglumine and gadopentetate dimeglumine.

PURPOSE To prospectively and intraindividually compare 0.1 mmol/kg gadobenate dimeglumine with 0.2 mmol/kg gadopentetate dimeglumine for contrast material-enhanced magnetic resonance (MR) angiography of the renal arteries. MATERIALS AND METHODS Institutional review board approval was granted by each of three participating centers. The study accorded with international standards for good clinical practice and Declaration of Helsinki and subsequent amendments. Patients gave written informed consent before enrollment. Patients (n = 34) underwent two MR angiographic examinations more than 48 hours but less than 12 days apart. Gadobenate dimeglumine followed by gadopentetate dimeglumine was administered in 18 patients; the order of administration was reversed in 16 patients. A 1.5-T MR imager was used with a phase-encoded three-dimensional spoiled breath-hold pulse sequence. Two blinded independent readers qualitatively assessed randomized subtracted maximum intensity projection images. A three-point scale for diagnostic quality (0, poor; 1a or 1p, moderate; and 2a or 2p, adequate [a and p refer, respectively, to absence and presence of vascular lesions]) was used to score each of nine segments of the abdominal aorta and both renal arteries (possible overall score, 18). Quantitative assessment (vessel signal-to-noise ratio [SNR], vessel-muscle contrast-to-noise ratio [CNR]) of source images was performed for regions of interest in supra-, juxta-, and infrarenal aorta segments and psoas muscle. Data were tested with analysis of variance for two-period crossover design. Interreader agreement was evaluated with Cohen kappa statistics. RESULTS No difference in mean image quality between the two contrast agents was observed; scores for gadobenate dimeglumine and gadopentetate dimeglumine were 15.15 and 15.23 for reader 1 and 16.77 and 17.01 for reader 2. The order of contrast material administration likewise produced no quality differences: readers 1 and 2 reported scores of 14.4 +/- 4.2 (standard deviation) and 16.7 +/- 2.3, respectively, when gadobenate dimeglumine was given first, and 15.2 +/- 1.8 and 16.6 +/- 1.6, respectively, when gadopentetate dimeglumine was given first. Results of quantitative evaluation showed increasing SNR and CNR with gadobenate dimeglumine in segments at progressively lower levels of the aorta, but increases in SNR and CNR at the infrarenal aorta (48.3 vs 40.6 and 44.2 vs 36.4, respectively) were not significant (P = .05 for both). CONCLUSION Gadobenate dimeglumine at a dose of 0.1 mmol/kg is comparable to gadopentetate dimeglumine at 0.2 mmol/kg for contrast-enhanced renal MR angiography.
Dementia from the inside: how people with early-stage dementia evaluate their quality of life.

People with Alzheimer's disease are sometimes hurt by others' responses to their disease. Having early stage dementia can lead to social isolation with people feeling devalued and even being made to feel they do not exist. One of the participants in this study said: 'When they know you have Alzheimer's they will just kind of ignore you. You are just there and that's it. They leave you alone because they figure you don't know what you're talking about, you don't know what is going on. ' The personal experiences of the negative view of dementia provided useful insights into the extent to which people with early stage dementia are affected by the stigma of the disease.
Cahiers du GRES

In this paper, we ask if the convergence in policies leads to a convergence in growth dynamics for MENA countries. We first show that FDI promotion policies have been very similar in the South East Mediterranean countries during the last decade. Then, we try to find clubs of convergence in this area through KPSS and ADF models, and show the difficulty of observing such clubs among Mediterranean countries.
Cultural Experience and Marketing

The cultural experience has the unique effect in the marketing practice.In order to raise the sales achievement,the enterprise may create the cultural experience for consumers by dredging up culture subject,giving prominence to cultural design of the commodity,setting up cultural image of the brand,making cultural atmosphere of the marketing environment and giving prominence to regional cultural characteristics and so on.
A heuristic approach for Periodic Vehicle Routing Problem: a case study

A heuristic approach is proposed to solve a real Periodic Vehicle Routing Problem (PVRP) that aims at extending the market share with the minimum transportation cost. In PVRP, vehicles are assigned to routes in different workdays to satisfy the frequency of visiting customers. The objective is to determine the scheduling and routing policies of the vehicles to minimise the fleet size and to maximise the selling benefits. The vehicle capacity and the trip time are the main constraints. The proposed approach is verified by real data and obtained results imply a significant improvement as compared to the current status.
Role of leukocytes in metabolic and functional derangements of experimental glomerulonephritis.

Nephrotoxic nephritis (NTN) is characterized by an influx of leukocytes into the glomerulus, with accompanying glomerular dysfunction and a marked increase in glomerular eicosanoid production. We examined the relationship between the glomerular inflammatory cell infiltrate and the concomitant metabolic/functional changes in this model of renal disease using a combination of in vivo immunologic strategies to both decrease [X-irradiation and cobra venom factor (CVF)] and increase (preimmunization with rabbit immunoglobulin G or accelerated NTN) the inflammatory cell infiltrate. With the use of these manipulations, a close correlation between glomerular leukocytes and the proteinuria of NTN was observed. The ablative strategies (X-irradiation and CVF) also attenuated the increase in leukotriene B4 (LTB4) generation seen with NTN and virtually completely prevented the increase in thromboxane B2 (TxB2) production (basal and angiotensin II elicited). Accelerated NTN, in contrast, increased and prolonged the rise in glomerular LTB4 production and exacerbated the increase in TxB2 production. Glomerular prostaglandin E2 production was not altered by the induction of nephritis nor any of the aforementioned immunologic manipulations. Regression analysis established that glomerular TxB2 production correlated significantly with the leukocyte influx at both 3 and 24 h. Glomerular LTB4 production correlated only with the presence of leukocytes at 3 h. Both glomerular TxB2 and LTB4 production were closely correlated with the renal dysfunction as assessed by proteinuria. These data suggest that leukocytes play a direct critical role in both the functional and metabolic alterations that occur in the setting of NTN. They further imply that leukocytes are crucial to the observed increase in glomerular eicosanoid production. (ABSTRACT TRUNCATED AT 250 WORDS)
The Impact of Government Financial Assistance on SMEs in Australia During the GFC

This paper uses firm-level data from the Business Longitudinal Database compiled by the Australian Bureau of Statistics to examine the effectiveness of government financial assistance provided to Australian small and medium-sized enterprises (SMEs) during the period surrounding the recent global financial crisis (GFC). We measure effectiveness in terms of subsequent firm performance (income and profitability) and improvement in the availability of alternative nongovernment finance. We find government financial assistance helps SMEs improve performance when compared to the effects of conventional financing. We also find than the implied guarantee effect whereby a firm receives government assistance suggests that firms are more likely to obtain nongovernment finance in the following year. Investors and creditors therefore benefit from the outcomes of government financial assistance. Finally, control factors that significantly affect SME performance and finance availability include size, the level of innovation, business objectives, and industry.