Miracle-dz/UniFAR-FTUs huggingface dataset:
A Novel Microwave Phased- and Perturbation-Injection-Locked Sensor With Self-Oscillating Complementary Split-Ring Resonator for Finger and Wrist Pulse Detection

In this article, a novel microwave phased- and perturbation-injection-locked (PPIL) sensor with a self-oscillating complementary split-ring resonator (SO-CSRR) is proposed for finger and wrist pulse detection. This SO-CSRR is designed to generate a concentrated electric field in the near-field region and then senses the skin-surface variations of the fingertip or the wrist artery, which are caused by the periodic capillary or vessel motion under the systolic and diastolic pressure states. When the fingertip is placed on the CSRR, the periodic variation of the skin leads to a periodic resonant frequency deviation based on the perturbation theory. This frequency deviation accompanies the corresponding phase shift. By injecting this phase-shifted signal into the SO-CSRR, it generates a frequency deviation at its output. This is the frequency-modulated signal, based on the injection-locked theory. Moreover, as the SO-CSRR is locked by the phase-locked loop, the vital-sign information contained in the frequency-modulated signal can be demodulated at the tuning-voltage terminal. The proposed sensor is called a PPIL sensor on account of its sensing mechanism and demodulation technique. In this article, the proposed sensor is employed to detect the finger and wrist pulses. Both the pulse interval and the waveform shape strongly agree with the results obtained using the photoplethysmography sensor. Since the proposed sensor has the benefits of having a simple system architecture, compact circuit size, and high sensitivity, it has great potential to be developed as a wearable sensor for healthcare applications.
Factors That Influence Force Steadiness in Individuals with Upper Limb Spasticity after Stroke

Individuals with post-stroke spasticity are disabled by paresis, soft-tissue shortening and muscle over-activity, which significantly affect functional motor output (FMO). Force steadiness (FS) describes the ability to maintain an isometric contraction, and is associated with functional task performance in healthy individuals. The coupling between FS and FMO suggests that FS may be a sensitive metric of FMO deficits that accompany spasticity that may not be captured using clinical scales. This thesis examined muscle weakness, muscle over-activity, and electromechanical coupling as potential factors influencing FS in upper limb spasticity. The affected limb was significantly less steady than the less-affected limb. Absolute force was negatively correlated with CV of force. However, co-activation indices were not different between limbs. Finally, flexor EMG was temporally correlated with force output. These measures may provide sensitive metrics of functional motor deficits that could be used as a tool to characterize effect of spasticity management interventions.
Clean Power Dispatching of Coal-Fired Power Generation in China Based on the Production Cleanliness Evaluation Method

China’s achievements in climate change and clean energy have been recognized by the international community. Although China has achieved successes in the field of clean energy, especially clean power dispatch, power dispatch is still one-sided and incomplete when considering environmental aspects. This paper presents a comprehensive production cleanliness evaluation model to assign a comprehensive environmental value as a reference for clean power dispatch. The model considers all the pollutants currently regulated in China’s coal-fired power plants, carbon emissions, and sustainability as three basic environmental constraints. Then, emergy analysis is used to unify the input/output materials with different units of measurement, and the emergy-based environmental value added (EEVA) value is constructed. As an integrated environmental value, the EEVA can provide an environmental reference for clean power dispatch. Finally, we selected a representative coal-fired power plant in China as a case study. By applying the above model, the dispatching sequence for four generating units was arranged from the perspective of cleanliness.
Recursive Filtering of Distributed Cyber-Physical Systems With Attack Detection

This article is concerned with the distributed recursive filtering of cyber-physical systems consisting of a set of spatially distributed subsystems. Due to the vulnerability of communication networks, the transmitted data among subsystems could be subject to deception attacks. In this article, attackers do not have enough knowledge of the full network topology and the system parameters and therefore cannot carry out stealth attacks. For this scenario, a defense strategy dependent on the received innovation is proposed to identify the occurring attacks as far as possible. In light of identified attacks, a novel distributed filter is constructed and its gain is designed via a set of recursive formulas on the upper bound of covariance of filtering errors. The utilization of upper bound is to avoid the calculational challenge of cross-covariance matrices and realize the requirement of distributed implementation, simultaneously. Furthermore, the developed scheme only depends on the neighboring information and the information from the subsystem itself, and thereby satisfying the requirement of the scalability. Finally, a standard IEEE 39-bus power system is utilized to verify the effectiveness of the proposed filtering scheme.
Risk-Adjusted Returns of Socially Responsible Mutual Funds II: How Do They Stack Up in Australia?

This article investigates the risk-adjusted performance of Australian socially responsible investment (SRI) mutual funds, their self-specified benchmark indexes, and an alternative SRI index from 2009 to 2019. Adopting a multifactor risk-adjustment model, the article examines whether Australian SRI funds are specifying appropriate benchmarks in terms of their environmental, social, and governance (ESG) investment strategies and risk profiles. The results indicate that Australian SRI fund managers neither outperform nor underperform their self-specified benchmark and alternative SRI indexes. In addition, Australian SRI funds are highly statistically related to their broad-based capitalization benchmark and alternative SRI indexes. While the results show that popular capitalization indexes are suitable proxies for Australian SRI fund performance benchmarking—and that managers seem to be specifying indexes that mirror the risk-adjusted return properties of their funds’ ESG investment strategies—it remains unclear as to why SRI funds are not selecting benchmarks that are ESG focused. TOPICS: ESG investing, analysis of individual factors/risk premia, performance measurement Key Findings • Australian SRI fund managers neither outperform nor underperform their self-specified benchmark and alternative SRI indexes. • Popular capitalization indexes are viable proxies for Australian SRI fund performance benchmarking, reflecting the risk–return properties of the funds’ ESG investment strategies. • It remains unclear why SRI funds are not selecting benchmarks that are ESG focused.
Dynamic pattern generation by singlemode fibers for endoscopic 3D measurement systems

This work presents experimental and simulation results of a 3D measurement concept based on fiber-optic interference pattern generation. A demonstrator system which is able to adjust different optical and mechanical parameters is described. The results of parameter variation studies are discussed along with possible applications in the field of micro-optical 3D measurement systems like endoscopes. The experiments were prepared with different structures with various scattering properties. To implement that approach into a micro-optical 3D measurement system, the combination of distance variation between the fibers and a controlled phase shift introduced by a retarder can be used to design the system versatile.
Ejection of Glycine Molecules Adsorbed on a Water Ice Surface by Swift-heavy Ion Irradiation

Organic molecules may be adsorbed on the ice surfaces of comets or moons. We study the desorption process induced by swift-heavy ion irradiation using a molecular dynamics simulation. Focusing on the amino acid glycine adsorbed on water ice as a prototypical example, we model a 2 MeV sulfur ion impact as it might be typical of magnetospheric ion impact on the surface of Europa. We find that molecules are ejected intact within a radius of up to 25 Å around the ion impact point. Within a core region of around 10 Å, glycine molecules are destroyed and mainly fragments are emitted. Prominent fragments produced are cyanide CN–, carbon monoxide CO, cyanate OCN–, and carbon dioxide CO2, in agreement with experimental studies. In addition, radiolysis of water ice generates the radicals H+, H3O+, and HO– as well as the gases H2, O2, and some H2O2. While the smaller fragments easily obtain velocities above 2 km s−1—the escape velocity from Europa—most ejected glycine molecules obtain smaller velocities and will thus not leave the moon permanently. Our results thus provide a detailed example that shows to what extent intact emission of organic molecules from Europa’s surface by ion irradiation is possible and may be used for modeling the height distribution of ejecta in Europa’s exosphere.
Abstract 1327: Variable impact of chemotherapy +/- cetuximab on immune modulation in a prospective cohort of 163 cancer patients

Introduction: Immunomodulation by anticancer agents is currently of major interest. We prospectively examined in 163 advanced cancer patients the impact of chemotherapy, combined or not with cetuximab, on relevant immune cell profile. Patients and Methods: 72 metastatic colorectal cancer patients received FOLFIRI, associated (N = 60) or not (N = 12) with cetuximab (Cetux), and 91 headn 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 1327. doi:10.1158/1538-7445.AM2015-1327
Forodesine IV (Bcx-1777) Is Clinically Active in Relapsed/Refractory T-Cell Leukemia: Results of a Phase II Study (Interim Report).

Background: Forodesine, a potent, rationally designed purine nucleoside phosphorylase inhibitor, has shown clinical activity in T-cell leukemia following IV administration. This phase II study was undertaken to evaluate further the efficacy and safety of IV forodesine in patients with relapsed/refractory T-cell acute lymphoblastic leukemia (T-ALL). Methods: In this open-label, single-arm, multicenter, ongoing study, patients received forodesine, 40 mg/m 2 IV, 5 days each week (1 cycle) for a total of 6 cycles. The dose was escalated to 90 mg/m 2 in patients who were not responding after cycle 2. The primary end point was objective response (OR), which included complete response (CR), CR with incomplete recovery of peripheral blood cell counts (CRi), and partial response (PR). Results: In total, 34 T-ALL patients (median age, 31 yr; range, 3–76 yr) with relapsed/refractory T-ALL (median, 3 prior treatments) received forodesine IV. The OR rate was 32.4% (11 patients; 7 [20.6%] CR, 0 CRi [0%] and 4 [11.8%] PR). Patient demographics and response for the 7 CR patients are shown in the Table. One CR patient has continued to receive treatment for almost 1 year. Two patients with CR proceeded to hematopoietic stem cell transplantation following remission. The restoration of normal hematopoiesis observed in patients while receiving therapy indicates a specificity of forodesine for leukemic cell populations. A total of 18 patients were dose escalated to 90 mg/m 2 of forodesine after cycle 2 due to a lack of response. None of these patients demonstrated an improved response with dose escalation. The most frequently reported possibly drug-related AEs without regard to grade were nausea (22%), headache (16%), thrombocytopenia (14%), leukopenia (14%), asthenia (14%), and anemia (11%). Possibly drug-related AEs of grade 3 and higher occurring in ≥2 patients were thrombocytopenia (3 patients; 8%) and leukopenia and lymphopenia (2 patients each; 5%). Conclusions: IV forodesine is effective as a single agent in the treatment of patients with relapsed or refractory T-ALL and is safe and well tolerated. Additionally, 40 mg/m 2 has been confirmed as the dose for subsequent phase II development in T-ALL.
Phishing Attacks: Preying on Human Psychology to Beat the System and Developing Cybersecurity Protections to Reduce the Risks

The evolution of technology over the years has allowed people to more easily store, access, and share information on the Internet. Â People can bank online, shop, and post their latest life news. Â Unfortunately, all this available information has attracted the attention of cybercriminals who want to use this personal information for fraudulent purposes. Â A common technique used by cybercriminals to obtain sensitive information is a scam called phishing. Â Criminals pose as a trusted entity in order to trick victims into revealing sensitive information that they will later use to commit illegal money transfers, identity theft, or other fraud. Â The consequences of phishing scams may lead to the loss of data, money, identity, reputation, and trust. Â As a result, organizations and individuals need to familiarize themselves with the process of a phishing attack and how to protect their systems and information. Â Organizations and individuals not only need the proper hardware and software to protect their information, but they also need to understand that cybercriminals prey on human psychology. Â Cybercriminals often use social engineering tactics to persuade people to willingly share their personal information. Â Therefore, cybersecurity policies and security prevention tips should address technical elements, as well as human behavioral factors that use the CIA (Confidentiality, Integrity, and Availability) model as a guide.
Sistem Kompresi Citra Berbasis Color Filter Array dan Transformasi 2-D Discrete Cosine pada Manga Reader

Efisiensi penggunaan bandwith dan memory menjadi satu fokus utama yang harus diperhatikan dalam setiap pemanfaatan teknologi terutama teknologi website dan mobile. Salah satu alternatif yang dapat di implementasikan adalah memperkecil ukuran data yang ditransfer lewat suatu jaringan protokol HTTP/S. Khusus untuk jenis citra, salah satu algoritma yang memiliki performa yang baik adalah jenis algoritma Discrete Cosine Transform. Sebelum proses kompresi dilakukan, terlebih dahulu citra di konversi ke mode hitam putih atau grayscale. Untuk algoritma konversi ini digunakan algoritma Bayer Color Filter Array dengan jenis mosaicing, dimana algoritma tersebut melakukan pemisahan 2 (dua) channel warna dari 3 (tiga) channel warna di masing-masing pixel pada citra dan mempertahankan mode warna dengan hasil RGGB. Penulisan dan penelitian pada tugas akhir adalah untuk mengimplementasikan algoritma Bayer Color Filter Array dan Discrete Cosine Transform pada manga reader berbasis web. Dari hasil pengujian dapat dibuktikan bahwa data citra dengan ukuran 138 kB akan menghasilkan rasio kompresi sebesar 42.75 % dengan menggunakan level kuantisasi 50 dan dengan level kuantisasi 10 akan menghasilkan rasio kompresi sebesar 23.18 % dari kompresi citra dengan penggabungan algoritma Bayer Color Filter Array Mosaicing dan 2D-Discrete Cosine Transform. Nilai PSNR yang didapatkan untuk hasil dekompresi dengan level kuantisasi 50 adalah 19,81 dB.
MALT BARLEY (HORDEUM VULGARE L.) WATER USE AND GRAIN YIELD RESPONSE TO SALINE IRRIGATION UNDER SHALLOW GROUNDWATER TABLE CONDITIONS

Global water scarcity and salinity of irrigated lands remain a concern. Shallow groundwater tables, often present in irrigation areas, may serve as energy‐efficient water sources, but they may also restrict leaching. This study quantified the salinity effects on water use and grain yield of irrigated malt barley in the presence of a shallow groundwater table. A lysimeter experiment was conducted over two seasons on sandy and sandy loam soils in Bloemfontein, South Africa. A Cocktail barley cultivar was irrigated with five irrigation water quality levels (ECi), i.e. control (1.5), 4.5, 6, 9 and 12 dS m−1. Salinity of the constant (1.2 m) groundwater table corresponded to ECi.
The safety of ramucirumab without H1-antihistamines as a premedication in patients with solid cancers: A retrospective study

Abstract Background Ramucirumab is a fully human monoclonal antibody (IgG1) developed for the treatment of solid tumors. To reduce the risk of an infusion-related reaction (IRR) with ramucirumab, H1-antihistamines are recommended as premedication. However, IRR is hardly observed in clinical practice in the ramucirumab regimen. The H1-antihistamines have several side effects, such as drowsiness and dizziness, and the use of H1-antihistamines might be restricted for the patients who need to drive a car or for elderly patients. The aim of this study was to investigate the safety of ramucirumab without H1-antihistamines as a premedication in patients with solid cancer. Methods We retrospectively reviewed the solid tumour patients who received ramucirumab, including regimen without H1-antihistamines at our institution between 2017 and 2019. The patients who received antiemetic steroid for cytotoxic chemotherapy was also included. The primary endpoint was the incidence of IRR during the infusion in the first cycle. The secondary endpoints were the incidence of IRR at any time and other ramucirumab related adverse events. Results Of the 51 patients enrolled (median age, 69.5 years; range 41 - 83), 28 (55%) were male. The origins of cancer were gastric cancer (n = 22), lung cancer (n = 26), and colon cancer (n = 3), respectively. Forty-two patients (82%) received ramucirumab in combination with antiemetic steroid for cytotoxic chemotherapy, and nine patients (18%) received ramucirumab monotherapy without steroid. No IRR was observed in this study (IRR rate, 0%; 95% CI 0 - 0.69). Among the overall 272 infusions, there were no events of IRRs or other ramucirumab related adverse events. Conclusions There was no IRRs without H1-antihistamines in our retrospective study. Ramucirumab without H1-antihistamines as premedication would be a favourable option for the patients who had trouble with the side effects of H1 antihistamine. Legal entity responsible for the study The authors. Funding Has not received any funding. Disclosure All authors have declared no conflicts of interest.
Pressure Dependence of Proton Incorporation and Water Solubility in Olivine

Hydrous forsterite single crystals were synthesized at 8 GPa and 1250 °C using a multianvil apparatus under various SiO2 activity conditions. Electron microprobe and transmission Fourier‐transform infrared spectroscopy analyses show that the Mg/Si atomic ratio increases with increasing water content. This provides new evidence that protons are mainly stored in Si sites in hydrous forsterite. The contribution of Mg sites for proton incorporation can be significant at ≤2.5 GPa with excess SiO2 but is negligible at higher pressures. Protons in olivine under asthenospheric conditions are therefore mostly maintained in Si sites. A summary of experimental studies suggests that the water solubility of forsterite/olivine equilibrated with excess (Mg,Fe)O is substantially higher than that with excess SiO2; however, this difference decreases with increasing pressure and becomes identical at 12–14 GPa. Owing to the low water solubility of olivine under topmost asthenospheric conditions, the geophysically observed low viscosity and low seismic velocity zones cannot be caused by olivine hydration, and the high conductivity anomaly should not be attributed to free H+‐controlled proton conduction in olivine.
Rehabilitation of Full Edentulous Mandible with Implants-supported Overdenture Using Attachments: Clinical Cases

56 Dalseong-ro, Jung-gu, Daegu 700-712, Korea Tel : +82-10-8854-3066 E-mail : pyi1024@dsmc.or. kr Abstract The rehabilitation of the fully edentulous patients, especially in mandible, could be compromised due to their diversity in terms of clinical, medical, anatomical and economic situations. An implant-retained complete overdenture is recommended as the gold standard in the oral rehabilitation of the edentulous mandible due to its relative simplicity, minimal invasiveness, predictability, efficacy and affordability. In this report, two fully edentulous patients under anticiagulatory therapy who were treated with a conventional complete denture on the maxilla and implant retained overdenture supported by freestanding implants placed in the anterior region of the mandible. Locator and magnetic attachments were used for retention of the mandibular overdenture respectively. Patients were satisfied with the final results in esthetic and functional aspects.
Silicon Micro and Nano Photonic Devices for Photonic Integrated Circuits

xiii List of Abbreviations Used . xiv Acknowledgements . xvii Chapter
Korrelative Bildgebung in der Kardiologie Theoretische Ansätze und klinische Anwendung

Abstract Technical progress has engendered a broad spectrum of methods to image cardiac structure, function, and metabolism. Frequently, the imaging tools available provide complementary information. Therefore, methods to integrate image information from differ-ent modalities into one common coordinate system are increasingly receiving attention also in cardiology. Currently available technology includes software-based image fusion as well as hardware-based regis-tration of datasets. The latter capitalizes on so-called hybrid cameras combining detectors of different mo-dalities in one gantry. Hardware-based image fusion is, to date, anatomically more accurate than the soft-ware-based methodology. However, the anatomic ac-curacy of both approaches is still far from perfect. This is, in particular, due to artifacts caused by respiratory movements also affecting the heart. The clinical po-tential of correlative imaging of the heart includes an improvement of accuracy in diagnosing hemody-namically significant coronary artery disease using single-photon emission computed tomography (SPECT). This is due to the possibility to correct myo-cardial scintigraphy for attenuation artifacts using registered X-ray computerized tomographic (CT) im-ages. The visualization of coronary anatomy and myo-cardial perfusion in one imaging session using hybrid systems combining CT with positron emission tomo-graphy (PET) or SPECT is also an interesting option. Nevertheless, larger clinical trials investigating its usefulness are still missing. The possibility to match structure with radioactivity concentration is essential for approaches to image the molecular composition of atherosclerotic plaques and their stability.
Deformation of Personality as a Consequence of a Hybrid Warfare

The article deals with the results of the theoretical and empirical research of the problem of deformation of a personality as a consequence of a hybrid warfare. To verify the theoretical conclusions concerning the phenomenon of deformation of a personality as a result of the hybrid warfare the main component of which is the informational and psychological influence on the population, the authors conducted a survey aimed at revealing the features of deformation of personalities of children of school age at the individual (psycho-physiological) and social and psychological levels It has been empirically verified that a part of the population of Ukraine experienced deformation of their personalities as a result of the hybrid warfare which is revealed at the individual (interchange of stable and critical psychical states, processes and features, mechanisms of social development, etc.) and psychological (negative changes at all the structural spheres of a personality – motivational, cognitive, volitional, interpersonal and creative ones) levels. A conclusion has been made about the necessity to provide social, psychological and pedagogical assistance for the population of Ukraine in order to overcome and minimize the negative personal deformations as a result of the hybrid warfare aimed at further successful socialization and development of a personality.