Miracle-dz/UniFAR-FTUs huggingface dataset:
Arterial hypertension as a population’s health problem in the prophylactic campaign “Ladies in red”

Wstep Celem pracy bylo zbadanie, czy i w jakim stopniu nadciśnienie tetnicze stanowi problem zdrowotny populacji badanej podczas akcji profilaktycznej, a takze ocena towarzyszących mu modyfikowalnych czynnikow ryzyka chorob sercowonaczyniowych. Material i metody Podczas akcji profilaktycznej „Kobiety w czerwieni” przebadano 240 osob w wieku 18–65 lat (120 kobiet oraz 120 mezczyzn). Pacjentow podzielono na trzy grupy. Grupa A (165 osob) skladająca sie z 83 kobiet (X1) i 81 mezczyzn (Y1) to osoby z ciśnieniem tetniczym prawidlowym. Grupe B stanowily osoby bez nadciśnienia tetniczego stwierdzonego w wywiadzie, ale z ciśnieniem tetniczym powyzej 140/90 mm Hg w wykonanych w trakcie akcji badaniach (30 osob: 13 kobiet - X2 i 17 mezczyzn - Y2). Do grupy C przyporządkowano pacjentow chorujących na nadciśnienie tetnicze - 45 osob, w tym 28 kobiet (X3) i 17 mezczyzn (Y3). W trakcie akcji dokonano pomiarow: ciśnienia tetniczego, masy ciala, wzrostu, BMI, wartości glikemii we krwi, procentowej zawartości tkanki tluszczowej, obwodu talii oraz bioder, zwrocono uwage na fakt palenia tytoniu, wywiad rodzinny oraz dotychczasowe leczenie. Do obliczen statystycznych zastosowano testy Kruskala-Wallisa, Manna-Whitneya oraz χ 2 . Do wyliczenia istotności badanych korelacji zastosowano wspolczynnik korelacji rang φ Spearmana. Wyniki Wykazano istotnośc statystyczną roznic miedzy średnimi wartościami: ciśnienia skurczowego (SBP) i rozkurczowego (DBP) miedzy grupami: A (116,3; 74,8) i B (144,5; 83,1) oraz A (116,3; 74,8) i C (138,7; 83,4); X1 (115,8; 75,8) i X2 (143,2; 82,5) oraz X1 (115,8; 75,8) i X3 (136,0; 81,4); Y1 (116,6; 73,8) i Y2 (145,6; 83,6) oraz Y1 (116,6; 73,8) i Y3 (137,1; 83,9); osob przyznających sie do palenia tytoniu (127,0; 79,4) i niepalących (123,0; 76,7); wieku w grupach Y1 (43,5) i Y3 (55,2); BMI w grupach X (24,3), Y (27,1); SBP z obwodem talii > 88 cm (134,0) i 25 (134,0) i 102 cm (136,0; 81,0) i 25 (131,0; 79,0) i Wnioski 1. Wykazano dodatnią korelacje pomiedzy wartością BMI, obwodu talii oraz paleniem tytoniu a wyzszą wartością SBP oraz DBP w badanej grupie osob. 2. Istnieje potrzeba zwrocenia szczegolnej uwagi na prowadzenie skutecznej prewencji pierwotnej oraz wtornej nadciśnienia tetniczego, a takze innych chorob ukladu sercowo-naczyniowego. 3. Wykazano istotnośc problemu nierozpoznanego nadciśnienia tetniczego zarowno w grupie mezczyzn, jak i kobiet w badanej grupie, gdyz u wszystkich tych pacjentow ryzyko wystąpienia incydentu sercowo-naczyniowego jest wyzsze niz przecietne, a w niektorych przypadkach, oprocz zalecanej zmiany stylu zycia, nalezy natychmiast wlączyc farmakoterapie hipotensyjną.
I. PENDAHULUAN eberapa dekade terakhir ini, teknologi komunikasi mengalami perkembangan yang sangat pesat. Perkembangan teknologi komunikasi menawarkan berbagai kemudahan untuk melakukan komunikasi dan pertukaran data pada sebuah jaringan. Saat ini, jaringan komunikasi telah berkembang luas seperti 

Abstrak— Sistem pengaturan berjaringan (SPB) berada pada persimpangan antara teori kontrol dan komunikasi. Pada umumnya teori kontrol menitikberatkan studi dari suatu sistem dinamik yang saling terkoneksi melalui “jalur ideal”, sedangkan teori komunikasi mempelajari perkembangan kemungkinan pengiriman data melalui “jalur tidak ideal”. Kombinasi dari dua jenis studi ini melahirkan konsep sistem pengaturan dengan komunikasi sensor, aktuator, dan kontroler yang terjadi pada jaringan komunikasi digital. Permasalahan yang muncul pada SPB berupa waktu tunda menjadi masalah tersendiri untuk menjaga kestabilan respon sistem. Pada tugas akhir ini dirancang suatu metode penalaan mandiri kontroler PID menggunakan adaptive fuzzy untuk mengusahakan perbaikan respon dan kestabilan pada sebuah sistem. Sehingga, keberadaan waktu tunda dan kehilangan paket data yang tidak menentu pada SPB dapat ditangani. Melalui perancangan kontroler PID dengan mekanisme tuning adaptive fuzzy didapatkan respon sistem yang mampu mengikuti set point dan mencapai keadaan steady dengan ess ± 0.12% dan memiliki %Mp = 0%. Pada pembebanan nominal didapatkan respon sistem dengan Ess = 0% dan %Mp = 0%. Pada pembebanan minimal dengan variasi delay didapatkan respon sistem dengan ess ± 0.5% dan memiliki overshoot dengan %Mp = 64% pada delay sebesar 0.38683 detik. Pada pembebanan maksimal dengan dengan variasi delay jaringan didapatkan respon sistem dengan ess ± 0.26% dan memiliki overshoot dengan %Mp = 7.12% pada delay sebesar 0.78683 detik.
for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Part 5: Adult Basic Life Support and Cardiopulmonary Resuscitation Quality Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

Introduction As with other Parts of the 2015 American Heart Association (AHA) Guidelines Update for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC), Part 5 is based on the International Liaison Committee on Resuscitation (ILCOR) 2015 international evidence review process. ILCOR Basic Life Support (BLS) Task Force members identified and prioritized topics and questions with the newest or most controversial evidence, or those that were thought to be most important for resuscitation. This 2015 Guidelines Update is based on the systematic reviews and recommendations of the 2015 International Consensus on CPR and ECC Science With Treatment Recommendations, “Part 3: Adult Basic Life Support and Automated External Defibrillation. ” In the online version of this document, live links are provided so the reader can connect directly to the systematic reviews on the ILCOR Scientific Evidence Evaluation and Review System (SEERS) website. These links are indicated by a combination of letters and numbers (eg, BLS 740). We encourage readers to use the links and review the evidence and appendix. As with all AHA Guidelines, each 2015 recommendation is labeled with a Class of Recommendation (COR) and a Level of Evidence (LOE). The 2015 Guidelines Update uses the newest AHA COR and LOE classification system, which contains modifications of the Class III recommendation and introduces LOE B-R (randomized studies) and B-NR (nonrandomized studies) as well as LOE C-LD (based on limited data) and LOE C-EO (consensus of expert opinion). The AHA process for identification and management of potential conflicts of interest was used, and potential conflicts for writing group members are listed at the end of each Part of the 2015 Guidelines Update. For additional information about the systematic review process or management of potential conflicts of interest, see “Part 2: Evidence Evaluation and Management of Conflicts of Interest” in this 2015 Guidelines Update and the related publication, “Part 2: Evidence Evaluation and Management of Conflicts of Interest” in the ILCOR 2015 International Consensus on CPR and ECC Science With Treatment Recommendations. Because this 2015 publication represents the first Guidelines Update, it includes an appendix with all the 2015 recommendations for adult BLS as well as the recommendations from the 2010 Guidelines. If the 2015 ILCOR review resulted in a new or significantly revised Guidelines recommendation, that recommendation will be labeled New or Updated. It is important to note that the 2010 recommendations used a previous version of the AHA COR and LOE classification system that was current in 2010. Any of the 2010 algorithms that have been revised as a result of recommendations in the 2015 Guidelines Update are contained in this publication. To emphasize that the algorithm has been modified, the words 2015 Update will appear in the title of the algorithm.
Dimensions of change detection within the phenomenon of change blindness

The phenomenon of change blindness (CB) has recently been investigated from a number of perspectives. Basically it entails the limited ability to perceive gross changes in one's visual environment. In a recent experiment, Simons and Levin (1998) showed that persons do not notice when a stranger asking them for directions is switched with another person when the switch is concealed briefly by two persons walking between them carrying a door. CB specifically pertains to limited ability to perceive disparity in scenes, changes between elements ('second-order information') and personal visual impressions (Rensink 2000:2). The rider is that the changes must occur during a flicker, saccade, blink, similar interruption or an eye movement (Simons & Levin 1997; Rensink 2000).
Defect-induced magnetism in graphite through neutron irradiation

We have investigated the variation in the magnetization of highly ordered pyrolytic graphite (HOPG) after neutron irradiation, which introduces defects in the bulk sample and consequently gives rise to a large magnetic signal. We observe strong paramagnetism in HOPG, increasing with the neutron fluence. We correlate the induced paramagnetism with structural defects by comparison with density-functional theory calculations. In addition to the in-plane vacancies, the trans-planar defects also contribute to the magnetization. The lack of any magnetic order between the local moments is possibly due to the absence of hydrogen/nitrogen chemisorption, or the magnetic order cannot be established at all in the bulk form.
Complexities of Protein Therapeutics and Immunogenicity

Biopharmaceuticals like monoclonal antibodies are widely used in clinical medicine for various therapies e.g. cancer, inflammatory and autoimmune diseases. Immunogenicity is one of the issues for safety. Such undesired immunogenicity can also limit the use of biopharmaceuticals, particularly for the treatment of chronic diseases that necessitate repeated treatments over long period. Assessment of immunogenicity is an important component of drug safety evaluation, which is presently performed by estimating risk factors. Risk based approach considers both probability of induction of immune response and expected clinical consequences. A combination of the two may result in high, medium or low risk levels and will depend on the product, patient and treatment related characteristics. Well engineered cells, well designed formulation coupled with good manufacturing scheme may sometimes reduce some of the extrinsic and intrinsic factors and increase the stability of drug product. One of the proposal for remedies is to purify the drug product to homogeneity or near homogeneity retaining its stability and functional activity. On the other hand, quite a few biosimilar drugs, which are supposed to be economical version of branded biotherapeutics, is expected to be in the market in next several years. Unfortunately, biosimilar manufacturing is often different from the brand name drug due to variation in manufacturing processes. As a result, such variations may trigger unwanted immunogenicity. Risk based approach, like branded drug, is more likely be required for drug development of therapeutic proteins for evaluation of immunogenicity followed by a development plan for risk mitigation.
Infrared Imaging and Neurofeedback: Initial Reliability and Validity

ABSTRACT Introduction. The neurological correlates underlying positive treatment outcomes for neurofeedback have been either unavailable or difficult to demonstrate. Assessment of brain-related changes associated with neurofeedback is needed to further establish its empirical basis. Infrared (IR) imaging is a noninvasive assessment of brain activity with high spatial and temporal resolution. Method. Study 1, a reliability study, assessed the test-retest stability of IR imaging. In Validity Study 2 and 3, IR imaging assessed brain-related changes prior to and following neurofeedback and passive infrared hemoencephalography (pir HEG) training, respectively. Results. In Study 1, high correlations occurred in pre-post comparisons for IR measures unrelated to treatment. Lower correlation between measures of IR imaging indicated changes in brain activation associated with thermoregulation following neurofeedback training. In Study 2, changes in thermal regulation occurred both within and across sessions. The ch.
USDA's Healthy Eating Index and Nutrition Information

A comprehensive model is developed to measure the extent that nutrition knowledge and diet-health awareness, among other factors, influence an individual's Healthy Eating Index (HEI), USDA's measure of overall diet quality. This is the first study that rigorously attempts to examine variation in the index across population groups by controlling for personal and household characteristics and nutrition information levels, as well as test for the endogeneity of nutrition information. Results indicate that one's level of nutrition information has an important influence on one's HEI and that nutrition information and the HEI are simultaneously determined. Other factors explaining variations in HEI's across individuals are income and education levels, race, ethnicity, and age. Evidence supports the hypothesis that higher education promotes more healthful food choices through better acquisition and use of health information.
VisiFit: AI Tools to Iteratively Improve Visual Blends

Iterative improvement is essential to the design process. However, iterative improvement requires difficult decisions about what to iterate on and requires the time and expense of making multiple prototypes. With the current advances in AI, there is the potential that AI can reduce these expenses and augment peoples’ ability to design. However, it is unclear what AI can reliably do and whether it should be fully automatic or if it needs human guidance. We explore how AI tools can assist novices in the difficult graphic design challenge of creating visual blends. First, we present four design principles for AI design tools based on co-design sessions with graphic designers. We introduce a system for iterating on visual blends by improving one visual dimension at a time. An evaluation of the tool on novices shows they can improve the blends beyond what existing novice tools can do in 97.5% of the cases and they produce publishable quality blends in 65% of the test cases. We discuss the implications for ways to combine human and computers’ abilities in the design process. Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than the author(s) must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from permissions@acm.org. CHI’20, April 25–30, 2020, Honolulu, HI, USA © 2020 Copyright held by the owner/author(s). Publication rights licensed to ACM. ISBN 978-1-4503-6708-0/20/04. $15.00 DOI: https://doi.org/10.1145/3313831.XXXXXXX Author
Detection and Estimation of Connection Splice Events in Fiber Optics Given Noisy OTDR Data — Part I : GSR / MDL Method

This paper proposes a novel method of detecting and locating connection splice faults (events) in fiber optics by the digital signal processing (DSP) of noisy optical time-domain reflectometry (OTDR) data. This is motivated by the fact that as fiber becomes more widely adopted as a communications medium, methods of automated fault detection/location will become more important. The approach taken is to use Gabor series expansion coefficients to coarsely localize the faults. Due to the presence of measurement noise, these coefficients are random variables, and it is Gabor coefficients with a nonzero mean that determine fault presence and location. Coefficients with nonzero mean are found with the aid of Rissanen’s minimum description length (MDL) criterion for model order estimation. The results herein show that the method is able to distinguish connection splice events from noise and the Rayleigh component in the OTDR data.
Novel Drug Development of the Next-Generation T790M Mutant SpecificEpidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for theTreatment of Advanced Non-Small Cell Lung Cancer

Lung cancer is a leading cause of cancer death worldwide. Lung cancer accounts for over 1 million mortalities annually and non-small cell lung cancer (NSCLC) accounts for almost 85% of all cases. Epidermal growth factor receptor (EGFR) mutations are found in approximately 10% and 30% of patients with NSCLC in North American/European and East Asian countries, respectively.
Population growth and structural transformation

This paper uncovers the mechanism and assumptions underlying how population growth induces structural transformation. We construct two-sector models that give analytically tractable closed-form solutions. If sectoral goods are consumption complements, population growth induces a more than proportionate relative price rise compared to the relative marginal product of labor drop in a sector with stronger diminishing returns to labor, and shifts production factors towards that sector. Our work points to a two-stage development process: (1) in early development, population growth shifts production factors to agriculture; and (2) when agricultural productivity growth is fast enough, production factors move out of agriculture.
Impact of Flexible Microcredit on Repayment and Food Consumption: Experimental Evidence from Rural Bangladesh

The mismatch between credit repayments and income seasonality implies a challenge for microfinance institutions (MFIs) working in developing countries. For instance in northern Bangladesh, income and consumption downfalls during the lean season after the transplanting of major paddy crops are a serious threat to the household economy. Poor landless agricultural wage laborers suffer the most due to this seasonality as they face difficulty to smooth their consumption. In designing microcredit products, MFIs do not usually provide any flexibility or seasonal adjustment during the lean season, however. This is mainly because MFIs are afraid of the possibility that such flexibility might break the repayment discipline of borrowers, resulting in higher default rates. We thus conducted a randomized controlled trial in 2011-12 in northern Bangladesh to test empirically whether flexible microcredit leads to an increase in repayment problems for MFIs and whether it can increase and stabilize consumption of borrower households. Our results suggest no statistically discernible difference among the treatment arms in case of default, overdue amount, or repayment frequency. This is in favor of flexible design of microcredit. On the other hand, we find no positive impact of the repayment flexibility on food consumption, either. This could be due to the possibility that the main problem for the ultrapoor is consumption smoothing between the lean and non-lean seasons, the insignificant difference in income changes across the credit schemes studied, or the treated households’ perception of the transient nature of the intervention.
Revue générale Effets chroniques des pesticides sur le système nerveux central : état des connaissances épidémiologiques Chronic central nervous system effects of pesticides : State-ofthe-art

Background. – Given the neurotoxic properties of pesticides, suggested by experimental results and clinical observations, many epidemiological studies have investigated neurological effects following acute or chronic exposure to pesticides. This review provides an overview of current knowledge about pesticide effects on the central nervous system: neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis), cognitive disorders, and psychiatric disorders (mood disorders, anxiety, depression and suicide). Results. – Parkinson’s disease, the most widely studied in relation with pesticide exposure, particularly with insecticides and herbicides, was observed to be a risk factor of the disease. Evidence is scarce for Alzheimer’s disease and amyotrophic lateral sclerosis, but quite consistent. Cognitive and psychiatric disorders were often observed in relation with organophosphate insecticide exposure. Cognitive disorders were found associated with acute and chronic exposures, and psychiatric disorders mostly with poisonings. These epidemiologic studies were limited by a lack of detailed and reliable exposure assessment. The role of genetic susceptibilities has been recently observed, but must be further investigated. # 2012 Elsevier Masson SAS. All rights reserved. Mots clés : Maladies du système nerveux central ; Maladies neurodégénératives ; Troubles mentaux ; Troubles cognitifs ; Suicide ; Dépression ; Pesticides
Habit persistence and asset pricing: Evidence from Denmark

We use an iterated GMM approach to estimate and test the consumption based habit persistence model of Campbell and Cochrane (1999) on quarterly Danish stock and bond returns over the period 1985-2001. For comparative purposes we also estimate and test the standard time-separable model based on power utility. In addition, we compare the pricing errors of the different models using Hansen and Jagannathan’s (1997) specification error measure. The empirical results, which are quite robust across different asset combinations and instrument sets, show that, i) neither the Campbell-Cochrane model nor the power utility model are statistically rejected by Hansen’s J-test; ii) pricing errors are of the same magnitude for both models;iii )t he risk-free rate is positive in the power utility model and mostly negative in the Campbell-Cochrane model; iv) in the Campbell-Cochrane model risk-aversion does not move countercyclically. These results suggest that - in contrast to what characterizes the US -, for Denmark the Campbell-Cochrane model does not perform better than the simple power utility model in explaining asset returns.
Orbit The International Journal on Orbital Disorders , Oculoplastic and Lacrimal Surgery

Corynebacterium amycolatum is a saprophyte gram-positive bacillus of the skin flora. It has been linked to diverse infections in immunocompromised patients and also of different types of prostheses. However, to our knowledge, there are no reports on its ability to produce ocular infections or to grow over alloplastic materials for orbital surgery. We present a case of orbital implant exposure including pure isolation of C. amycolatum. The patient was referred for discharge in his socket. After removal of the artificial eye, a large area of implant exposure and signs of chronic infection were observed. A microbiological sample was taken by rubbing the implant with a sterile swab. The sample was cultured and C. amycolatum was identified by phenotypical characterization. Other microbial species were not isolated. Besides being able to adhere to cardiac and joint devices, this case shows that C. amycolatum is a potential infectious agent of orbital prostheses. Pure isolation of C. amycolatum in an ocular sample is extremely rare and suggests an etiological role of this microorganism in an ocular or periocular infection. ARTICLE HISTORY Received 7 May 2016 Accepted 28 May 2017
econd traitement conservateur radiochirurgical dans les récidives locales du ancer du sein econd conservative radiosurgical treatment for ipsilateral breast cancer recurrence

Département de radiothérapie oncologique, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex, France Département de chirurgie mammaire, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex, France Département d’anatomopathologie, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex, France Département de radiologie, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex, France Département d’oncologie médicale, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex, France