Miracle-dz/UniFAR-FTUs huggingface dataset:
Designing a Career Plateauing Model in Departments of Sports and Youth Based on the PLS-SEM Approach

Background. The behavior and attitudes of employees with Plateauing not only include themselves, but also makes all members of the group in which they work to ask whether they are really suitable for the organ in which they work. Objectives. This study is to design a model of Plateauing of employees of departments of Youth and Sport of northwestern provinces of Iran. Methods. In the present study, a mixed strategy (quantitative and qualitative data), indepth interviewing in the qualitative sector and exploratory factor analysis was used. The construct validity of the questionnaire was confirmed by Cronbach's alpha of 0.839 and according to Krejcie Morgan table, a sample size of 181 individuals was determined through cluster sampling. A total of 63 indicators were identified as influencing factors on the Plateauing of the employees of departments of Youth and Sports of northwestern provinces in the form of an 11 sub-factors and five main factors. Results. Investigating exploratory factor analysis, confirmatory factor analysis, and structural equation analysis showed that each of the main factors of skill factor (lack of technical skills and lack of work maturity) (p<0.05; T=11.07), psychological factor (lack of personal motivation, lack of external reward) (p<0.05; T=11.93), inside work factor (lack of job flexibility, lack of job transparency, and lack of promotion) (p<0.05; T=13.56), intra organizational factor (lack of proper training and lack of work communication) (p<0.05, T=14.82), and managerial factor (lack of manager support and dissatisfaction with management style) (p<0.05; T=14.49), are respectively influencing the Plateauing of the employees of departments of Youth and Sports of northwestern provinces. Conclusion. It should be mentioned that by increasing organizations with flat structure and decreasing management positions at the medium level, the possibility of vertical promotion of employees in organizations has been decreased. The prevalence of organizational Plateauing is one of the consequences of failure to compete for tenure of jobs at organizational levels, so it is clear that performing repetitive tasks and working in uniform jobs increases the phenomenon of occupational Plateauing.
Correlation of in vitro chemotherapy drug resistance assay to clinical response to carboplatin and paclitaxel combination chemotherapy in ovarian carcinoma.

e16546 Background: Carboplatin sensitivity in drug resistance assays has been shown to be an independent predictor of longer progression free interval with conflicting results in overall survival. We evaluated in vitro drug resistance for carboplatin and paclitaxel combination and its correlation with progression free survival (PFS) and overall survival (OS). Methods: From April 1, 2006 to December 12, 2011, in vitro drug resistance assays were sent after cytoreductive surgery for primary epithelial ovarian cancer. Patients were analyzed according to drug resistance scoring system of low drug resistance (S), intermediate drug resistance (I), and extreme drug resistance (R). Retrospective chart review was performed to evaluate PFS and OS. The Kaplan Meier product limit method was used to estimate OS and PFS. Survival curves were compared between groups using the log rank test. Results: From a total of 142 patients: 57 were S, 52 I, and 33 R; 77% were responsive (S+I) to carboplatin and paclitaxel combinati.
Synthesis of Bis-GMA and UDMA Nanofibers for Reinforcing Experimental resin-composites: Influence on Degree of Conversion, Depth of Cure, Flexural Strength, Flexural Modulus and Fracture Toughness

Objectives: To study the degree of conversion, depth of cure, flexural strength, flexural modulus and fracture toughness of experimental resin-composites reinforced with Bis-GMA and UDMA nanofibers synthesized by electrospinning technique.Materials and methods: Bis-GMA (Bis-GMA+TEGDMA+PEGDMA) and UDMA (UDMA+PEGDMA) nanofibers were synthesized by wet electrospinning technique and characterized by Scanning Electron Microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). After ball-milling to a nanoscale size (< 100 nm) in a ball-milling machine (Retsch – PM 400, Haan, Germany), these nanofibers were added to a prepared experimental resin-composite. According to the percent and type of added nanofibers, this study was divided into eight groups (n=10/group): one control group, three groups reinforced with 7, 11 and 15 wt% Bis-GMA nanofibers and four groups reinforced with 7, 11, 15 and 20 wt% UDMA nanofibers. For each of these groups, the degree of conversion (DC), depth of cure (DoC), flexural strength (FS), flexural modulus (Ef) and fracture toughness (FT) were studied. DC was studied using the FTIR method (FTIR, Model: EQUINO X55, Bruker, Germany). DoC was measured according to ISO 4049: 2009a. FS testing (and Ef calculation) was carried out according to ISO 4049:2009 by a three-point bending test. FT testing was conducted according to ISO/FDIS 6872:2007. Data were collected and submitted to One-way ANOVA and post-hoc Tukey test with the significance level set at (p ≤ 0.05). Results: Pure forms of Bis-GMA (70-100 nm) and UDMA (50-100 nm) nanofibers were confirmed by SEM and FTIR. One-way ANOVA revealed significant differences for flexural strength (p = 0.001), flexural modulus (p = 0.001) and fracture toughness (p = 0.001) but not for neither degree of conversion (p = 0.078) nor depth of cure (p = 0.879). For both types of nanofibers, compared to the control group, reinforced groups showed greater FS and FT and comparable DC and DoC results. For Ef, except the group reinforced with 7 wt% Bis-GMA,all groups exhibited lower values than that of the control group. Within the range of studied properties, Bis-GMA nanofibers exhibited more favourable results than UDMA nanofibers.Conclusions: Synthesis if Bis-GMA and UDMA nanofibers could be successfully accomplished by electrospinning to be used for resin-composite reinforcement. At a certain ratio (7 wt%), these fibers recorded improvement in FS and FT while keeping Ef, DC and DoC unchanged.
Sex Toys: Acceptance among Chinese Youth of Kampar, Perak. Alat Permainan Seksual: Penerimaan Di Kalangan Belia Cina Di Kampar, Perak

This paper investigates the acceptance of sex toys among youth in Kampar, Perak which is dominated by the Chinese community. Sex toys are designed to facilitate the satisfaction of human sexual pleasure and to assist masturbation during foreplay leading to physical sexual intercourse. This study is done in light of alarming incidences of unprecedented pregnancy that lead to infant-dumping cases, rape cases, the sexually transmitted Human Immunodeficiency Virus (HIV) and increasing rate of Acquired Immune Deficiency Syndrome (AIDS) patients. Using a quantitative approach, stratified-sampling data are gathered via survey questionnaires targeting the Chinese youths living in Kampar, Perak. By capturing the youth’s attitude on sex toys, we aim to identify their level of knowledge and acceptance of sex toys. The findings show that sex toys are not commonly known among the youths. They are also found unaware on how to use the sex toys as most of the youth is actually unfamiliar with the function of the sex toys. Due to their perceptions that sex toys might harm and not beneficial to them, the youths reject the using of sex toys to fulfill their sexual satisfaction.
Pathology And Genetics Of Tumours Of The Lung Pleura Thymus And Heart

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FRACTURE STRENGTH AND MARGINAL GAP OF RE-PRESSED IPS E.MAX PRESS CROWNS WITH DIFFERENT CONCENTRATIONS

Objective: The aim of this study was to investigate the effect of repressing IPS e.max Press with different concentrations on the marginal gap and fracture strength of ceramic crowns.Materials and methods: Twenty-five IPS e.max Press crowns were fabricated. They were divided into 5 groups (5 samples in each group) according to the Wt. % of the new ceramic ingots to the repressed ceramic. Group I is 100 % new ceramics. Group II is 75 % new and 25% repressed ceramics. Group III is 50 % new and 50 % repressed ceramics. Group IV is 25% new and 75% repressed ceramics. Group V is 100 % repressed ceramics. Each crown was seated on the copper mold and the marginal gap was measured at 16 predetermined points using a computer connected stereomicroscope. For fracture strength test the crowns were luted using resin cement on epoxy dies and subjected to fracture strength test. Results: Group 1 (100 % new) recorded the least marginal gap (32.7 µm), while group 5 (100% repressed) recorded the highest marginal gap (120.91 µm). No statistical significant difference between marginal gap of the first three groups (100 % new, 75% new + 25% repressed, 50% new + 50% repressed). A statistically significant difference was recorded between these 3 tested groups and group 4 (25% new + 75% repressed). There was also a significant difference between group 4 and group 5 (100% repressed). Fracture strength results showed that Group I (100 % new) recorded the highest fracture strength (929.724 N), while group III (50% new) recorded the least fracture strength (819.366N). A statistical significant difference was found between the first four groups and a siginficant difference between GroupV (100% repressed) and Group I,II,III. While, there was no significant difference between Group IV and Group V.Conclusions: It was found that various weight percentages of repressed ceramics affected the marginal gap and had a significant effect when it exceeded 50 %, although all tested groups were clinically accepted. Also, homogeneity of the ceramic structure had a positive effect on fracture strength, as the least fracture strength was recorded for the 50% new + 50% repressed ceramic group and it increased significantly as this relation increased towards either the new ingot ceramics or the repressed ceramic:
TeamTags: Domination – An A-GPS game for mobile phones

Mobile devices and wireless data connectivity are getting more and more common nowadays. In this networked world there are going to be dozens of new applications. Location Based Services will play a major role in this area. Especially, with the current and upcoming UMTS enabled mobile phones these applications are going to be available to a larger number of customers. The most promising approach to get accurate position data on a phone is to use GPS or the enhanced Assisted GPS which is part of the UMTS standard. We developed a mobile game especially designed to demonstrate the possibilities of an Assisted GPS empowered mobile phone.
How to Adapt Deep Learning Models to a New Domain: The Case of Biomedical Relation Extraction

In this article, we study the relation extraction problem from Natural Language Processing (NLP) implementing a domain adaptation setting without external resources. We trained a Deep Learning (DL) model for Relation Extraction (RE), which extracts semantic relations in the biomedical domain. However, can the model be applied to different domains? The model should be adaptable to automatically extract relationships across different domains using the DL network. Completely training DL models in a short time is impractical because the models should quickly adapt to different datasets in several domains without delay. Therefore, adaptation is crucial for intelligent systems, where changing factors and unanticipated perturbations are common. In this study, we present a detailed analysis of the problem, as well as preliminary experimentation, results, and their evaluation.
Immediate rehabilitation of atrophied mandible with “All on four” implant supported fixed prosthesis with and without cantilever extensions. One year clinical

Aim: The purpose of this study was to evaluate clinical and radiographic results of implant supported fixed prosthesis with and without cantilever extensions for “All on four” implant rehabilitation of atrophied mandible. Materials and methods: Ten completely edentulous individuals with atrophied mandibular ridges were classified into 2 groups: 1) Group I: included 5 patients with posteriorly placed mental foramen, 2) Group II: included 5 patients with anteriorly placed mental foramen. All participants were managed by 4 implants according to the “All on four” protocol using a Nobel Biocare metal guide and open flap surgery. Implants were immediately loaded by existing mandibular dentures. Group I restored with fixed prosthesis without cantilevers, and group II restored with fixed prosthesis with distal short cantilevers. Plaque and gingival index, probing depth, implant mobility and bone loss (using cone beam CT) were evaluated after prosthesis delivery (T0), six months (T6) and 12 months (T12) after delivery Results: For posterior implants, group II showed significant higher plaque index, and gingival index than group I after 6 and 12 months. No differences in probing depth, implant mobility and bone resorption between groups was noted for anterior and posterior implants. Posterior implant showed significant higher plaque scores (for both groups) and gingival scores (for group II) than anterior implants after 6 and 12 months. Posterior implant showed significant higher pocket depth for both groups. Conclusion: Within the limitation of this study, fixed prosthesis with short cantilever can be used successfully to rehabilitate patients with atrophied mandibular ridges and anteriorly placed mental foramen with “All on four” concept as it was associated with favourable clinical and radiographic outcomes similar to prosthesis without cantilevers
Epimedium Aqueous Extract Improves Osteoporosis and Regulates PPARγ, GSK-3β and β-Catenin Expression in Ovariectomized rats

Context: Epimedium brevicornu Maxim. , a Chinese herb, has long been used to treat osteoporosis. Its antiosteoporosis effect may be related with the Wnt/β-catenin signaling pathway. Objectives: To investigate the effects of aqueous extract of Epimedium in ovariectomized rats via regulating the Wnt/β-catenin signaling pathway in the treatment of osteoporosis. Materials and methods: After ovariectomy, three-month-old female Sprague Dawley (SD) rats (n = 84) were randomly divided into six groups: Sham, ovariectomized (OVX), positive group (10 mg/kg/day alendronate sodium tablets), AE-Low, AE-Middle and AE-High group (0.11, 0.33 and 0.99 g/kg/day aqueous Epimedium extract respectively, based on the Epimedium clinical dose and the equivalent dose ratio of human-animal surface area). After 12 weeks treatment, bone mineral density (BMD), biomechanical testing, bone micro-architecture was observed, and serum osteocalcin (OCN), osteoprotegerin (OPG), mRNA and protein expression levels were measured. Results: In comparison to OVX, treatment with AE had positive effects on BMD, trabecular number (Tb.N), trabecular thickness (Tb.Th) and changes in serum markers of bone turnover as well as improved the maximum load. Moreover, the AE treatment group could significantly reverse the increase of peroxisome proliferatorsactivated receptor γ (PPARγ) and glycogen synthase kinase 3β (GSK-3β) and the decrease of runt-related transcription factor 2 (Runx2) and β-catenin mRNA expression due to ovariectomy. Discussion and conclusions: AE was shown to exert anti-osteoporotic effect on ovariectomized rat through regulating the key proteins in the Wnt/β-catenin signaling pathway, which may provide a potential mechanism to study its role in further population research.
Microencapsulation of Zn-chlorophyll pigment from Pandan leaf by spray drying and its characteristic

Microencapsulated compound of Zn-chlorophyll derivatives extracted from pandan leaf by using spray dried method can be utilized as a natural green colorant. Three different wall material types, gum arabic (GA), maltodextrin (MD) and osa-modified starch (MS), were studied based on their physicochemical properties and stabilities of the encapsulated powder. Results showed that MS powder was spherical and smooth, whereas GA and MD powders exhibited shrinkage on the surface. At 30% MS as wall material, Zn-chlorophyll powder obtained had the highest greenness value, total chlorophyll and antioxidant activity as -14.64, 187.34 mg/100gfw and 772.50 μMTEAC/g fresh mass, respectively. The MS powder provided a longer predicted half life (462 days) compared to the GA and the MD powders. This powder had green color, 2-acetyl 1pyrroline as volatile compound with pandan leaf characteristic flavor and Zn content of 13.12 mg/kg which was safe to use as food additive.
Cytokines and Inflammatory Mediators for Monitoring the Status of Periodontitis

Objective: C-reactive protein is a sensitive and dynamic systemic marker of inflammation. Pro- and anti-inflammatory cytokines have been well documented with initiation, control and susceptibility to periodontal diseases. This study applied high-sensitivity CRP (Hs-CRP), pro- and anti-inflammatory cytokines to predict risk of periodontal diseases. Methods: 2200 subjects (1200 healthy subjects and 1000 chronic periodontal patients) were recruited from community of Hong Kong, Department of Periodontology and Oral Medicine, Xiangya Hospital, Central South University, Hunan, China, respectively. Blood was drawn from subjects and DNA was extracted. The polymorphic sites of C-Reactive Protein (CRP), proinflammatory (interleukin-1α (IL-1α), IL-1β, Tumor Necrosis Factor-α (TNF-α), IL-6 and IFN-γ) and anti-inflammatory cytokines (IL-4, IL-10) were amplified and measured via polymerase chain reaction for further analysis. Chi-square test and logistic regression analysis were applied to analyze genotype distribution differences, allele frequencies and carriages rates between healthy and disease groups. Soluble protein levels of cytokines were evaluated by the t-test. Results: Genotype frequencies of CRP, pro- and anti-inflammatory cytokines was statistically higher in periodontal-diseased patients than healthy controls (p<0.05). Prevalence of periodontal diseases was statistically correlated with carriage of single nucleotide polymorphisms of the cytokine parameters. Conclusions: Hs-CRP and cytokine gene polymorphisms may be applied as biomarkers to predict periodontitis susceptibility, clinical behavior and severity.
Aberystwyth University A metabolomic study in oats (Avena sativa) highlights a drought tolerance mechanism based on salicylate signalling pathways and the modulation of carbon, antioxidant and photo-oxidative metabolism

Although a wealth of information is available on the induction of one or several drought-related responses in different species, little is known of how their timing, modulation and crucially integration influence drought tolerance. Based upon metabolomic changes in oat (Avena sativa L.), we have defined key processes involved in drought tolerance. During a time course of increasing water deficit, metabolites from leaf samples were profiled using direct infusion–electrospray mass spectroscopy (DI-ESI-MS) and high-performance liquid chromatography (HPLC) ESI-MS/MS and analysed using principal component analysis (PCA) and discriminant function analysis (DFA). The involvement of metabolite pathways was confirmed through targeted assays of key metabolites and physiological experiments. We demonstrate an early accumulation of salicylic acid (SA) influencing stomatal opening, photorespiration and antioxidant defences before any change in the relative water content. These changes are likely to maintain plant water status, with any photoinhibitory effect being counteracted by an efficient antioxidant capacity, thereby representing an integrated mechanism of drought tolerance in oats. We also discuss these changes in relation to those engaged at later points, consequence of the different water status in susceptible and resistant genotypes. Key-words: metabolomics; photorespiration; salicylic acid. Abbreviations: DFA, discriminant function analysis; DI-ESIMS, direct infusion–electrospray mass spectroscopy; Fv/Fm, the ratio of variable fluorescence (Fv) over the maximum fluorescence (Fm); m/z, mass-to-charge ratio. Indicate the dimensionless quantity formed by dividing the ratio of the mass of an ion to the unified atomic mass unit, by its charge number (regardless of sign). To make easier manuscript reading, ‘m/z’ has been replaced in some places by the word ‘metabolite’; PCA, principal component analysis; ROS, reactive oxygen species; SA, salicylic acid.
An Ontology for Role Playing Games

—In this paper, we introduce a new, comprehensive ontology specially designed for modeling Role-Playing Games semantics. We build on top of a foundational ontology approach, namely Uniﬁed Foundational Ontology, to cover elements from Interactive Storytelling and aspects from a game’s narrative. Experimental results using two well-known, representative titles from the electronic and the analog supports, respectively, shows promising ﬂexibility and effectiveness in terms of competency questions.
Transforming Growth Factor – β and Glioma

Transforming growth factor-beta (TGF-β) is a regulatory cytokine secreted by various types of cell such as stromal cell, immune cells and tumor cells. Signaling of TGF-β plays an important role in proliferation, differentiation and apoptosis regulation of various cell, including glial cell. Disruption in the signaling pathway of TGF-β is commonly seen in tumor cells and is believed to contribute to the initiation and progression of cancer cells. Changes in the chromosome accompanied by genetic mutation has been observed which causes TGF-β to act as an oncogene, a substance which promote normal cells to differentiate to cancer cells.Increased level expression of TGF-β molecules has been seen in more malignant gliomas which yields a lower prognosis for the patient compared to those with lower expression of TGF-β. Malignant gliomas are characterized by rapid proliferation, invasion of parenchyma and angiogenic capabilities, are most common type of primary brain tumors. Studies have now implemented specific targeted therapy which act as a treatment for glioma cases. This review will focus on the role of TGF-β in glioma and its application in the treatment of glioma. International Journal of Human and Health Sciences Vol. 04 No. 03 July’20 Page : 156-160
A Systematic Review of the Efficacy of Repetitive Transcranial Magnetic Stimulation as Treatment for Posttraumatic Stress Disorder

Repetitive transcranial magnetic stimulation (rTMS) is an alternative treatment option for drugresistant mental illnesses, such as Major Depressive Disorder (MDD). More recent clinical trials have investigated whether rTMS can also be used in the treatment of Posttraumatic Stress Disorder (PTSD). To synthesize current evidence on the use of rTMS to treat PTSD, a qualitative systematic review was carried out. This review focused on clinical trials that featured both a comparison group and distinct scales to separate PTSD symptoms from any comorbid illnesses. Presently, rTMS seems to be a relatively safe treatment for PTSD, however, it is likely no more effective than current treatments. Additionally, missing clinical trial data casts doubt on whether the present literature is representative of the true effect of rTMS on PTSD. Based on these conclusions, rTMS does not seem a suitable replacement for more popular treatments. However, rTMS is a relatively affordable and noninvasive treatment option, and may be worth continued investigation as an option for those with drug-resistant PTSD, in particular.