Miracle-dz/UniFAR-FTUs huggingface dataset:
Utilización de granos de destilería deshidratados con solubles (GDDS) en dietas para conejos de ceba

Para evaluar la inclusion de 0, 10, 20 y 30 % de granos de destileria deshidratados con solubles (GDDS) en dietas para conejos de ceba, se utilizaron 56 conejos (Negro Azteca x Chinchilla) de 40 d de edad. Se determino el comportamiento productivo a partir de las ganancias de peso, conversion alimentaria, viabilidad, consumo de alimento, ganancia media diaria, rendimiento en canal, carne, huesos y grasa de los conejos, asi como el rendimiento en visceras comestibles. La viabilidad fue de 100 % en todos los tratamientos. Los conejos que consumieron la dieta con 10 % de GDDS consumieron menos alimento (91.8 g/conejo), lo que determino mejor indice de conversion alimentaria (4.21). Los conejos que recibieron la dieta con 20 % de GDDS fueron los que obtuvieron mayor peso (2051 g/conejo). El rendimiento en canal no difirio significativamente entre tratamientos. Los conejos que ingirieron la dieta con 30 % de GDDS lograron mayor rendimiento en visceras comestibles (8.8 %). El rendimiento del cuello fue mayor en los conejos que consumieron la dieta con 20 % de GDDS (4.9 %). No hubo diferencias significativas para rendimiento en carne y grasa en la canal. Es posible incluir hasta 20 % de GDDS en los piensos para conejos de ceba, sin alterar su comportamiento productivo.
An Infrastructure for Secure Interoperability of Agents

Abstract : Introduction Building distributed applications is difficult. Therefore, it is hardly surprising that in spite of all the hoopla surrounding the Internet and distributed computing, truly distributed applications are few and far between. The problem seems to be with the tools available to developers of distributed applications. For example, the most widely used mechanism for distributed computation is the remote procedure call (RPC), the first implementation of which dates back to the early 1980s. Typically, a remote procedure call is executed on a server on behalf of a client (the so-called client-server model). It is hardly surprising therefore that most distributed applications today are exclusively based on the client server architecture. A lot can be (and has been) accomplished with this architecture, as exemplified by the World Wide Web and HTTP, a protocol that implements RPC. However, the client-server model has a number of limitations. There are problems of fault tolerance, load balancing, survivability, dynamic reconfiguration, rollover recovery, and distribution of control. Attempts in the past to break through this bottleneck have had only limited success.
Auditieve verwerking van spraak: Hoe weinig we ervan weten

De centrale vraag bij de auditieve verwerking van spraak is hoe de luisteraar erin slaagt het continu varierende en ook in andere opzichten zeer variabele akoestische signaal te herleiden tot een reeks discrete eenheden – hetzij fonemen, hetzij woorden. Enkele tientallen jaren onderzoek hebben geen bruikbaar model van dit proces opgeleverd. In het foneemperceptie-onderzoek is er nauwelijks sprake van toetsbare modellen. Zo menen we bijvoorbeeld te weten dat spraak categorisch wordt waargenomen, maar we weten niet hoe dat gebeurt – en om die vraag gaat het nu juist. Ook het woordherkenningsonderzoek heeft niet geleid tot een model van auditieve verwerking van spraak, voornamelijk omdat het zich niet met de centrale vraag bezighield. Er bestaan goede fysiologische modellen van de verwerking van geluid, en dus ook van spraak, vanaf het perifere gehoororgaan tot in de auditieve cortex, bij proefdieren. Uit die modellen wordt duidelijk dat de herleiding van signalen tot discrete eenheden niet ergens op dit pad gebeurt: het zit dus “hogerop”. De verwachting is dat onderzoek naar die hogere niveaus, dankzij de opkomst van niet-invasieve fysiologische meetmethoden die op mensen gebruikt kunnen worden, ons in de komende jaren een beter beeld zullen geven van de auditieve verwerking van spraak.
Signal detection for polarization multiplexing QAM optical coherent receivers using ESN

Coherent optical systems face two main categories of linear impairments, chromatic dispersion (CD) and polarization mode dispersion (PMD). Both CD and PMD will create large inter-symbol interference (ISI). This paper focuses on M-quadrature amplitude modulation (QAM) signal detection directly using Echo State Networks (ESN) technique for compensating (residual CD and PMD) dispersion of coherent optical systems. The proposed approach can estimate directly the input sequence at the coherent receivers, without getting the electronic equalizer coefficients and estimating optical channel impulse response. In addition, the proposed approach can guarantee a convergence within a short data packet.
Large-scale oceanic features detected by airborne SAR in the Mediterranean sea

During the MAC-Europe Campaign in June/July, 1991, the NASA JPL synthetic aperture radar (SAR) carrying a polarimetric 3-frequency SAR operating at 440 MHz (P-Band), 1.25 GHz (L-Band) and 5.30 GHz (C-Band) flew several missions over the Gulf of Genoa and the Strait of Messina. On June 22, 1991, SAR images were taken over the Gulf of Genoa showing an anti-cyclonic eddy south of Genoa having a diameter of approx. 15 km. Model calculations carried out by V. Casulli, (University of Trento) and G. Mansella (ENEA, La Spezia) show that this eddy is generated by the modification of the steady cyclonic circulation caused by wind forcing and the interaction with the coastline and the bathymetry. This model result is also substantiated by AVHRR images. On June 28, 1991, SAR images were taken over the Strait of Messina showing a strong non-linear interval wave train south of the Strait of Messina. This wave train was imaged several times. By correlating successive SAR images the propagation speed of the internal waves is determined. During the passes over the Strait of Messina the JPL SAR was operated in an interferometric SAR-mode by using two antennas. Surface current velocities as well as correlation times are derived from these interferometric data (R. Carande, JPL). The airborne SAR images are compared with radar images acquired by the C-band SAR aboard the First European Remote Sensing Satellite ERS-1 over the Strait of Messina. Several of these ERS-1 SAR images display surface manifestations of internal waves. They are interpreted in terms of theoretical models on the generation of internal waves in the Strait. <<ETX>>
of HIV Susceptibility Markers T Cell Subset Coexpressing Multiple + Characterization of a Human Cervical CD4

Arthos, Joshua Kimani and Rupert KaulKatharine E. Block, Claudia Cicala, A. Omu Anzala, JamesIzulla, Makobu Kimani, Sanja Huibner, Lawrence Gelmon, Lyle R. McKinnon, Billy Nyanga, Duncan Chege, Prestonhttp://www.jimmunol.org/content/187/11/6032doi: 10.4049/jimmunol.1101836November 2011;J Immunol€2011; 187:6032-6042; Prepublished online 2Referenceshttp://www.jimmunol.org/content/187/11/6032.full#ref-list-1This article cites 53 articles, 20 of which you can access for free at: Subscriptionshttp://jimmunol.org/subscriptionsInformation about subscribing to The Journal of Immunology is online at: Permissionshttp://www.aai. org/ji/copyright.htmlSubmit copyright permission requests at: Email Alertshttp://jimmunol.org/cgi/alerts/etocReceive free email-alerts when new articles cite this article. Sign up at:
Nationale und internationale Schulleistungsstudien: was können sie leisten, wo sind ihre Grenzen?

In der Bundesrepublik Deutschland gibt es keine Tradition der dauerhaften Beobachtung von Erträgen institutionalisierter Bildungsprozesse. Dies gilt für den Fachleistungsbereich ebenso wie für die breiten Bereiche der sozial-kognitiven und motivationalen Entwicklung. Ein Hauptinteresse der Erziehungswissenschaft lag in den letzten 10 bis 15 Jahren mit gutem Grund auf der Entwicklung und Erprobung von Modellen zur Optimierung der Arbeit in Einzelschulen und dem Entwurf didaktischer Modelle und deren Einführung in die Unterrichtspraxis. Die Selbstvergewisserung über das insbesondere im Unterricht Erreichte und Erreichbare trat demgegenüber in den Hintergrund.
Utility of photodynamic therapy for the management of oral potentially malignant disorders and oral cancer

Photodynamic therapy (PDT), defined as “the light-induced inactivation of cells, microorganisms, or molecules,” combines the use of a photosensitive agent or photosensitizer (PS) activated by irradiation with a light source to produce reactive oxygen species and highly reactive singlet oxygen. PDT has been used for the treatment of different oral diseases with promising results. This review describes the basic principles of PDT, including the nature of PS and the light sources, and focuses on evaluating the efficacy of this method, according to the existing data, for the treatment of different oral diseases. PubMed was used as the source of the relevant literature, about the clinical application of PDT in actinic cheilitis (AC), leukoplakia, oral lichen planus, oral lichenoid lesions, and oral cancer. Complete response to PDT as high as 100% has been reported not only in cases of AC but also in dysplasias/carcinomas in situ, T1N0, and T2N0. According to the available data, PDT appears to be a safe, well-tolerated therapy with limited adverse effects and excellent cosmetic outcome. Although PDT is a very promising therapy, further research is needed in order to investigate the cases that fail to respond, to examine the long-term prognosis for cases of reported complete response and thus avoid the future recurrence of diseases.
Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia.

BACKGROUND Cardiac arrest outside the hospital is common and has a poor outcome. Studies in laboratory animals suggest that hypothermia induced shortly after the restoration of spontaneous circulation may improve neurologic outcome, but there have been no conclusive studies in humans. In a randomized, controlled trial, we compared the effects of moderate hypothermia and normothermia in patients who remained unconscious after resuscitation from out-of-hospital cardiac arrest. METHODS The study subjects were 77 patients who were randomly assigned to treatment with hypothermia (with the core body temperature reduced to 33 degrees C within 2 hours after the return of spontaneous circulation and maintained at that temperature for 12 hours) or normothermia. The primary outcome measure was survival to hospital discharge with sufficiently good neurologic function to be discharged to home or to a rehabilitation facility. RESULTS The demographic characteristics of the patients were similar in the hypothermia and normothermia groups. Twenty-one of the 43 patients treated with hypothermia (49 percent) survived and had a good outcome--that is, they were discharged home or to a rehabilitation facility--as compared with 9 of the 34 treated with normothermia (26 percent, P=0.046). After adjustment for base-line differences in age and time from collapse to the return of spontaneous circulation, the odds ratio for a good outcome with hypothermia as compared with normothermia was 5.25 (95 percent confidence interval, 1.47 to 18.76; P=0.011). Hypothermia was associated with a lower cardiac index, higher systemic vascular resistance, and hyperglycemia. There was no difference in the frequency of adverse events. CONCLUSIONS Our preliminary observations suggest that treatment with moderate hypothermia appears to improve outcomes in patients with coma after resuscitation from out-of-hospital cardiac arrest.
Is Newer Better: A Comparison of Web and Paper-Pencil Survey Administration Modes.

The use of Web-administered surveys by colleges and universities is becoming more prevalent as the Web mode can be more cost efficient and less intrusive on class time than the traditional paper-pencil mode. The purpose of this study was to compare several potential survey issues by mode to see if the Web mode was as viable an approach as the more traditional paper-pencil. Of particular concern were coverage error, nonresponse error, response set, and the psychometric qualities of the data collected. Data from three postsecondary institutions that had administered the American College Testing program's "Student Opinion Survey" first on campus using the paper-pencil mode and then via Web were used. The total number of respondents from all 3 institutions was 1,874 in 1997 (paperpencil) and 1,251 in 2001 (Web). Findings from the study indicated that the two modes were comparable, with the Web mode perhaps allowing for more representative sampling. (Contains 9 tables and 12 references.) (Author/SLD) Reproductions supplied by EDRS are the best that can be made from the original document. Is Newer Better: A Comparison of Web and Paper-Pencil Survey Administration Modes Anji Sun Randy McClanahan ACT, Inc. Email: Anji.Sun@act.org or Randy.McClanahan@act.org PERMISSION TO REPRODUCE AND DISSEMINATE THIS MATERIAL HAS BEEN GRANTED BY TO THE EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) Is Newer Better I U.S. DEPARTMENT OF EDUCATION Office of Educational Research and Improvement EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) 1pThis document has been reproduced as received from the person or organization originating it. Minor changes have been made to improve reproduction quality. Points of view or opinions stated in this document do not necessarily represent official OERI position or policy. O 00 Presented at the O 2003 Annual Meeting of the American Educational Research Association Chicago, IL
Textbook of Uncommon Cancer

It might seem at first sight that the last book a general physician or surgeon would need is a Textbook of uncommon cancer. This subject should surely be the province of the expert and he or she will know about it anyway. Nobody, be they generalists or specialists, who looks after patients with cancer, however devoted to their subject, will not at some time have experienced a sudden feeling of inadequacy on seeing a rarity on the histopathologist's report. Rapid recourse to a standard textbook may be disappointing and a computer search leaves one with a great deal of paper with information that is difficult to assess. This book is going to be helpful for it brings together much information on clinical presentation, pathology, diagnosis and management of innumerable rare cancers classified on the basis of either site or system. The organisation of the book has a logic of its own but, no matter, the individual contributions from British, American, European, Australian and Japanese experts are of a uniformly high quality. I very much hope that the editors will include the haemopoietic lymphoid system and paediatric tumours in their next edition as this leaves
Automated video chain optimization

Video processing algorithms found in complex video appliances such as television sets and set top boxes exhibit an interdependency that makes it is difficult to predict the picture quality of an end product before it is actually built. This quality is likely to improve when algorithm interaction is explicitly considered. Moreover, video algorithms tend to have many programmable parameters, which are traditionally tuned in manual fashion. Tuning these parameters automatically rather than manually is likely to speed up product development. We present a methodology that addresses these issues by means of a genetic algorithm that, driven by a novel objective image quality metric, finds high-quality configurations of the video processing chain of complex video products.
Hybrid time- and frequency-domain speech synthesis with extended glottal source generation

A novel synthesis approach that combines speech synthesis in the time domain with speech synthesis in the frequency domain is introduced. The intention is to improve speech quality by designing a hybrid system which profits from the advantages of both methods and overcomes some of their drawbacks. Compared to a stand-alone formant synthesizer, a better quality of fricatives and plosives has been achieved, whereas the flexibility in fundamental frequency variation is preserved. Moreover, simultaneous use of both system components enables the system to produce naturally sounding transitions at the segment boundaries. The parametric part of the hybrid system-a formant-based synthesizer-is excited with a time-domain source generation scheme. It is based on concatenation and modification of stored natural source waveforms. Important system features are phoneme-specific variants of stored source waveforms and additional generation of shimmer and jitter. Preliminary informal listening tests showed that the naturalness of the voiced sounds has been improved compared to the results of the previous synthesizer. <<ETX>>
Early prediction of cisplatin nephrotoxicity in head and neck cancer patients – An evaluation with urinary biomarkers

Background: Nephrotoxic Acute Kidney Injury (AKI) is a common condition associated with considerable morbidity and mortality. Acute exposure to potentially nephrotoxic drugs requires early appraisal of the extent of renal injury to determine the need for specific interventions. Hence this study was designed to evaluate two urinary biomarkers for the early diagnosis of AKI due to cisplatin chemotherapy, including Neutrophil gelatinase-associated lipocalin (uNGAL) and Cystatin C (uCysC). Methods: Urinary biomarker levels in cisplatin treated cancer patients were estimated before and at 2hrs, 6hrs, 12hrs, 24hrs and 48hrs after cisplatin administration. Diagnostic performances of biomarkers were studied by ROC analysis with AUC and predictive values. Results: uNGAL was identified as the earlier biomarker of AKI induced by cisplatin as it detected kidney injury as early as 2hrs after the exposure of nephrotoxic drug with an AUC of 0.8, which is 46hrs before the elevation of serum creatinine. uCysC detected AKI 6hrs after cisplatin administration with AUC 0.73. Conclusion: Indication of AKI by biomarker elevations can provide an early warning signal which may have implications in therapy by either stopping the nephrotoxic drug or reducing its dose or even by substituting it with a less nephrotoxic one. The research in this direction should focus on evolving rapid procedures with an eventual point-of-care test for urinary biomarker determinations that will transform the scope of biomarkers significantly in the field of early renal injury.
Innovazione tecnologica e cambiamento dell’università : verso l’università virtuale

Il lavoro, frutto della collaborazione tra alcuni docenti e ricercatori delle Facolta di Scienze della Formazione e di Ingegneria dell'Ateneo fiorentino, mette a punto alcuni concetti ed apparati teorici di riferimento sul tema delle innovazioni tecnologiche per l'offerta didattica, coniugando la letteratura internazionale con la specificita del contesto italiano
A DATA MINING METHODOLOGY WITH PREPROCESSING STEPS

This paper analyzes various problems that appear while performing data mining. The issues of data quality are discussed. The main focus is set on feature selection and its influence on classification results. Feature selection, or discovery of an optimal data set is a process of removing features from the data set that are not useful in decision making, and leaving the most useful ones. The influence of feature selection is analyzed for different classification algorithms. They are applied on two different (in constitution) data sets to solve three problems of medical domain. Presented results show that there is no universal algorithm, whitch could help solving any problem, as well as each data set has its own optimal (sub)set suitable for the classification algorithm. Methodological recommendations to reach possibly optimal solution are given to perform clinical decision support.
The Effect of Study Design on Gain in Evaluations of New Treatments in Medicine and Surgery*

We analyzed the results of 128 comparisons of an innovation with a standard treatment in medicine, and 221 comparisons in surgery, to relate features of study design to the magnitude of gain. The mean gain (measured by the Mann- Whitney statistic) for the innovation over standard therapy was relatively constant across study designs, except for nonrandom trials with sequential assignment to therapy. These trials showed a significantly higher likelihood that a patient would do better on the innovation than on standard therapy. In medical trials that used sequential assignment of refractory patients, the mean gain (measured as the Mann — Whitney statistic) was 0.94, compared to the mean gain for randomized controlled trials of 0.62 (p <. 01). In surgery, the mean Mann- Whitney statistic for nonrandom sequential studies evaluating primary treatments was 0.78, compared to 0.56 for randomized controlled trials (p<. 01). In the evaluation of both medical and surgical therapies, randomized control trials that used a placebo control were significantly more likely to produce a gain for the innovation. In medicine, the Mann- Whitney statistic was 0.72 for placebo controlled trials and 0.61 for nonplacebo controlled trials (p=0.04). In surgery, the average Mann-Whitney statistic was 0.60 for 12 double-blind trials that used placebos, and 0.52 for 10 double-blind trials that did not. When interpreting an evaluation of a new therapy, we may consider adjusting the results of studies that have used sequential assignment so that the average bias, as reported in this article, may be taken into account. Likewise, in studies that have used a placebo control, the Mann- Whitney statistic could also be adjusted downward by . 10 if a standard treatment is available. These adjustments provide a more realistic appraisal of the new treatment until stronger studies supersede them.
Inhibition of dipeptidyl peptidase 4 by BI-1356, a new drug for the treatment of beta-cell failure in type 2 diabetes

BI 1356, a xanthine-based DPP-4 inhibitor, has reached Phase III trials. The compound efficiently inhibits dipeptidyl peptidase 4 (DPP-4) in vitro and in vivo. In vivo GLP-1 levels increase to levels at or above the levels of other DPP-4 inhibitors. Preclinical trials suggest a once-daily administration of 5 mg to be efficient, long-lasting and without known side effects.
Influence de la température sur l'élasticité d'un solide

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Pattern-based target selection applied to fund raising

This paper proposes a new algorithm for target selection. This algorithm collects all frequent patterns (equivalent to frequent item sets) in a training set. These patterns are stored e? ciently using a compact data structure called a trie. For each pattern the relative frequency of the target class is determined. Target selection is achieved by matching the candidate records with the patterns in the trie. A score for each record results from this matching process, based upon the frequency values in the trie. The records with the best score values are selected. We have applied the new algorithm to a large data set containing the results of a number of mailing campaigns by a Dutch charity organization. Our algorithm turns out to be competitive with logistic regression and superior to CHAID.