Miracle-dz/UniFAR-FTUs huggingface dataset:
Management of Postprandial Blood Glucose in Diabetes Mellitus

Patients with type-2 diabetes have more than half the day in the post meal state. Elevation in post meal plasma glucose is due to loss of first phase insulin secretion, decreased insulin sensitivity in peripheral tissues and consequent decreased suppression of hepatic glucose output after meals due to insulin deficiency. Elevated or exaggerated post meal response is directly responsible for endothelial dysfunction and pro-atherogenic states. Post-meal hyperglycemia is a prominent early defect in type-2 diabetes patients.
Conceptualizing the foundations of a regional e-commerce strategy: Open networks or closed regimes? The case of CARICOM

Abstract Although there has been much to boast about in advanced countries regarding e-commerce as a viable business strategy, many doubt its application to developing countries. Several papers examine individual case studies from advanced developing countries but few have presented a systemic focus on the ecosystem of an e-commerce sector, and even fewer on small island developing states (SIDS) such as the Caribbean, and those often lack a comprehensive awareness of the sector, and/or are dated. The central aim of this conceptual paper therefore is to address this lacuna by discussing the importance of understanding the broader political, social, cognitive, and economic issues and their implications and applications inherent in the development of an e-commerce sector. From this, the main objective will be to conceptualize an e-commerce strategy for their development. To realize this main aim, the article leverages a historical comparative perspective that critically examines causal analysis, experiences, and iterative processes gleaned over time from a structured analytical comparison of several national and regional case studies to conceptualize the factors and conditions under which e-commerce may contribute to, and can be adopted for development. As its main objective, the paper then presents a policy framework of recommendations guided by mutually reinforcing macro processes of change that converge at the intersection of business, policy, and information technology to inform development advocates, policy planners, and citizens within the region of what such a strategy should entail.
Can Insertion Sequences Proliferation Influence Genomic Plasticity? Comparative Analysis of Acinetobacter baumannii Sequence Type 78, a Persistent Clone in Italian Hospitals

Acinetobacter baumannii is a known opportunistic pathogen, dangerous for public health mostly due to its ability to rapidly acquire antibiotic-resistance traits. Its genome was described as characterized by remarkable plasticity, with a high frequency of homologous recombinations and proliferation of Insertion Sequences (IS). The SMAL pulsotype is an A. baumannii strain currently isolated only in Italy, characterized by a low incidence and a high persistence over the years. In this present work, we have conducted a comparative genomic analysis on this clone. The genome of 15 SMAL isolates was obtained and characterized in comparison with 24 other assemblies of evolutionary related isolates. The phylogeny highlighted the presence of a monophyletic clade (named ST78A), which includes the SMAL isolates. ST78A isolates have a low rate of homologous recombination and low gene content variability when compared to two related clades (ST78B and ST49) and to the most common A. baumannii variants worldwide (International Clones I and II). Remarkably, genomes in the ST78A clade present a high number of IS, including classes mostly absent in the other related genomes. Among these IS, one copy of IS66 was found to interrupt the gene comEC/rec2, involved in the acquisition of exogenous DNA. The genomic characterization of SMAL isolates shed light on the surprisingly low genomic plasticity and the high IS proliferation present in this strain. The interruption of the gene comEC/rec2 by an IS in the SMAL genomes brought us to formulate an evolutionary hypothesis according to which the proliferation of IS is slowing the acquisition of exogenous DNA, thus limiting genome plasticity. Such genomic architecture could explain the epidemiological behavior of high persistence and low incidence of the clone and provides an interesting framework to compare ST78 with the highly epidemic International Clones, characterized by high genomic plasticity.
Prognostic impact of CD 4-positive T cell subsets in early breast cancer

Background: The clinical importance of tumor-infiltrating cluster of differentiation 4 (CD4) T cells is incompletely understood in early breast cancer. We investigated the clinical significance of CD4, forkhead box P3 (FOXP3), and B cell attracting chemokine leukocyte chemoattractant-ligand (C-X-C motif) 13 (CXCL13) in early breast cancer. Methods: The study is based on the patient population of the randomized FinHer trial, where 1010 patients with early breast cancer were randomly allocated to adjuvant chemotherapy containing either docetaxel or vinorelbine, and human epidermal growth factor receptor 2 (HER2)-positive patients were also allocated to trastuzumab or no trastuzumab. Breast cancer CD4, FOXP3, and CXCL13 contents were evaluated using quantitative real-time polymerase chain reaction (qRT-PCR), and their influence on distant disease-free survival (DDFS) was examined using univariable and multivariable Cox regression and Kaplan-Meier estimates in the entire cohort and in selected molecular subgroups. Interactions between variables were analyzed using Cox regression. The triple-negative breast cancer (TNBC) subset of the HE10/97 randomized trial was used for confirmation. Results: High CXCL13 was associated with favorable DDFS in univariable analysis, and independently in multivariable analysis (HR 0.44, 95% CI 0.29–0.67, P ≤ 0.001), most strongly in TNBC (HR 0.39, 95% CI 0.19–0.79, P = 0.009). No significant interaction with chemotherapy or trastuzumab administration was detected. Neither tumor CD4 content nor FOXP3 content was associated with DDFS. The favorable prognostic influence of CXCL13 was confirmed in the HE10/ 97 trial patient population with TNBC (HR 0.30, 95% CI 0.09–0.93; P = 0.038). Conclusions: The results provide a high level of evidence that humoral immunity influences the survival outcomes of patients with early breast cancer, in particular of those with TNBC. Trial registration: The study reports retrospective biomarker analyses in the prospective FinHer trial and the prospective HE10/97 trial. ISRCTN76560285. Registered on 18 March 2005. ACTRN12611000506998. Registered on 16 May 2011.
FERTILITY STATUS OF VEGETABLE GROWING AREAS OF PESHAWER, PAKISTAN

The study was conducted to classify soil of vegetable growing areas of Peshawar with respect to low, medium and high soil fertility status for better management of the whole area. A total of 36 soil samples were collected from different sites surrounding Peshawar city at 0-30 and 30-60 cm depths. Soil samples were analyzed for soil chemical properties and soil fertility status. The data of chemical properties of soil showed that soil pH in both the depths was alkaline in nature and non saline. Organic matter was found deficient and medium in 27 and 55% samples in surface soil while it was deficient and medium in 44 and 55% samples in subsurface soil. Total nitrogen was found deficient and medium in 27 and 61% samples in surface soil while it was found deficient and medium in 44 and 55 % samples in sub surface soil. Ammonium Bicarbonate Di-ethylene Triamine Penta Acetic Acid extractable phosphorus was found deficient and medium in 27 and 11% samples in surface soil while it was found deficient and medium in 33 and 22% samples in sub surface soil. AB-DTPA extractable potassium was found medium and adequate in 44 and 55% samples in surface soil while it was found medium and adequate in 66 and 33% samples in sub surface soil . AB-DTPA extractable copper and manganese were found adequate in all the samples. AB-DTPA extractable iron was found medium and adequate in 11 and 88% samples in surface and sub surface soil. AB-DTPA extractable zinc was found deficient, medium and adequate in 33, 11 and 55% samples in surface soil while it was found deficient, medium and adequate in 44, 16 and 38% samples in sub surface soil. Hence it is recommended that areas which are deficient in P, Zn, and Fe should be fertilized with variable rate of respective fertilizers.
Examining the Impact of Anxiety Symptoms on Relations between Reactive and Proactive Aggression and the Quality and Stability of Children's Best Friendships

The current study examined anxiety symptoms as a moderator of the relation between reactive and proactive aggression and the quality and stability of children’s relationships with their best friend. An at-risk sample of 132 (55% male; 73% African American) 5 to 14-year-old children from low-income families was recruited from a community center that offered childcare to underserved populations. Data were collected at baseline and two months later, with the second wave of data collection yielding a sample of 79 children. Structural equation modeling was used to examine relations between baseline levels of reactive and proactive aggression and friendship quality and stability two months later. Additionally, anxiety symptoms measured at baseline were examined as a moderator of the relations between these functions of aggression and the quality and stability of children’s best friendships. Contrary to hypotheses, no first order effects were found for either reactive or proactive aggression predicting friendship quality or stability. A first order effect was found in which child anxiety predicted a greater likelihood of friendship instability. However, levels of anxiety symptoms were not found to influence perceived level of friendship quality. Additionally, anxiety was not found to moderate the relations between reactive or proactive aggression and either friendship success variable. Posthoc analyses failed to find differences for gender or age.
Non-invasive Detection of Troponin I for Heart Attack Prevention

Regardless of precautions taken to prevent heart attacks, the fact remains that these are still the leading causes of death. According to the World Health Organization report, 59% of deaths were the result of non communal conditions. Of which, 29% of deaths were related to cardiovascular complications. This corresponds to approximately 10 million people in a year die resulting from cardiovascular complications. Most heart attacks could be maintained if the patient is to receive essential medical attention in time. Missed acute myocardial infarction (AMI) is the leading subject of medical malpractice claims against hospital emergency rooms and primary care. On the other hand admission of patients with a low probability of AMI often leads to excessive and unnecessary hospital costs. Cardiac biomarkers play an important role in determining the level of AMI risk. cTnI (Cardiac Troponin I) is a cardiac specific protein released into blood after inception of cardiac damage and is considered one of the most specific cardiac biomarkers. The purpose of this study is to design a portable real-time monitoring system for detection of heart attack at its early stages using non-invasive biophotonic measurements. For this purpose, Fluorescence, and Raman spectroscopy methods have been investigated. After a complete scan through cTnI sample using a Spectrofluorometer, fluorescence excitation wavelength of known concentrations of purified recombinant cTnI was found to be 283nm as expected due to existence of Tryptophan amino acid in the protein. The emission wavelength of protein for various molarities was acquired to be 347nm with elevated spectrum amplitude for higher protein concentrations. The regression graph of the concentration vs. fluorescence amplitude shows a 0.99 correlation, confirming linear relationship of cTnI fluorescence amplitude with respect to increase in concentration. A distinct Raman signature of cTnI sample diluted separately in Tn Buffer Complex and water have been acquired using Raman Spectrometer which demonstrates increase in amplitude of the Raman signature as molarities of the sample change. SYSTEM OVERVIEW
Effects of surfactant addition on dewatering of alum sludges

In Taiwan, surfactants are frequently used in the flotation process to aid in solid/liquid separation. Their effect on the dewatering of alum sludge was investigated. Various amounts of cationic and anionic surfactants were added to sludge samples, and the dewatering characteristics of the sludge and the water content of sludge cakes were evaluated. Both surfactants improved the dewatering of the sludge by lowering the specific resistance to filtration, decreasing the bound water content, and increasing the dewatering rate of the sludge. Different combinations of anionic and cationic surfactants and polyelectrolytes were also experimented on to study the effect of surfactant addition on the dewatering characteristics of polyelectrolyte-conditioned sludge. Experimental results indicated that both cationic and anionic surfactants adversely affected the dewatering of the conditioned sludge. The addition of surfactant to the oppositely charged polyelectrolyte proved to be most detrimental to sludge dewatering.
Spin ordered phase transitions in neutron matter under the presence of a strong magnetic field

In dense neutron matter under the presence of a strong magnetic field, considered in the model with the Skyrme effective interaction, there are possible two types of spin ordered states. In one of them the majority of neutron spins are aligned opposite to magnetic field (thermodynamically preferable state), and in other one the majority of spins are aligned along the field (metastable state). The equation of state, incompressibility modulus and velocity of sound are determined in each case with the aim to find the peculiarities allowing to distinguish between two spin ordered phases.
The Effect of Different Compositions to Substructure and Dielectric Properties of Ba1-xSrXTiO3 Thin Films Modified Using Sol-Gel Process

Thin films perovskite Barium Strontium Titanate Ba (1-x) SrxTiO3 (BST) for x=0.1; 0.2 and 0.3 structure type is a hopeful microelectronic devices that can be structured with semiconductor technology. In this research different composition these thin films prepared using sol-gel process. The perovskite structure of these materials can be obtained by controlling the substrate temperature. The samples were annealed at 700°C for 1 h in air. Microstructure and dielectric properties studies show that Sr improve as the compositions increase. All the films have a grain size in nanometers. The average grain size and cross-section of the film increases due to an increase in the composition Sr. The values of the dielectric constant of the film is also increased due to an increase in average grain size. The results showed the microstructure and dielectric properties depending on the composition.
Unexploited Agricultural Growth: The Case of Crop-Livestock Production Systems in Zimbabwe

Livestock is the most important source of cash for small-scale farmers in the semi-arid tropics of southern Africa. However, with limited access to markets, farmers do not have the incentive to invest in improved livestock management. Livestock production and off-takes remain low and farmers are unable to realize the full potential of their herds. We believe that improved market access will be the driver to increase technology adoption for income growth and poverty reduction. In Zimbabwe, a recent baseline diagnosis by ICRISAT and partners found that cash income from goats is crucial to cover day-to-day expenditures for food, education and human health. Cattle are more important for draft power and milk, and support subsistence cropping activities. Major production constraints include high mortality rates attributed to dry season feed shortages, particularly affecting farmers with small herds. An increasing demand for livestock products in rural and urban areas offers small-scale farmers opportunities for market participation. However, the existing markets are underdeveloped, with high transaction costs implying low producer prices and poor access to information for farmers. The challenge is to sustain livestock production, develop more effective market facilities, and thereby increase off-take. The potential of market-led technology development in crop–livestock systems has not been sufficiently exploited by research and development. To have an impact on incomes and poverty, we develop an innovative approach that would first evaluate local constraints in production and marketing, and then test alternative livestock markets and management strategies, with a strong linkage between private and public sectors
Effect of nickel toxicity on growth parameters and hepatic enzymes in major carp

Labeo rohita were used to investigate effect of nickel induced toxicity. For this two groups, control groups (N=50) and experimental groups (N=50) were further divided into group 1-4, on the basis of dosage of nickel and blood sampling. Body weight of animals was noted before and after dose treatment. It was found that body length in the experimental group did not show marked increase throughout experimental period while the effect of nickel toxicity was observed on body weight. The weight of experimental fish decreased in experimental group significantly (p<0.05) from first dose to the last dose. Blood plasma was analyzed for biochemical parameters (Total proteins, AST, ALT, and ALP). AST, ALT and ALP levels increased remarkably in experimental fish as compared to the control one, while the levels of total proteins decreased significantly from group 1-4. Results of the present study suggest hepatotoxicity caused by metal and role of nickel as endocrine disrupter in fish body. Nickel also causes changes in growth parameters of animal by affecting their body weight with increased dosage of metal.
Fuzzy Model For Human Face Expression Recognition

Facial expression recognition plays a vital and effective role within the interaction between man and computer. In this project, brand new system supported the mathematical logic is projected for this purpose. Fuzzy is one helpful approach for fuzzy classification, which might verify the intrinsic division in an exceedingly set of untagged knowledge and notice representatives for undiversified teams. This method acknowledges seven basic facial expressions particularly concern, surprise, happy, sad, disgust, Neutral and anger. For description of detail face facial features, Face Action writing (FACS) was style. First, we tend to gift a unique methodology for facial region extraction from static image. For determination of face effective areas is employed from integral projection curves. This methodology has high ability in intelligent choice of areas in facial features recognition system. Extracted face expression fed to fuzzy rule based mostly system for facial features recognition. Results of tests indicate that the projected theme for facial features recognition is powerful, with smart accuracy and generating superior results as compared to different approaches. Facial expression analysis has been attracted goodly attention within the advancement of human machine interface since it provides natural and economical thanks to communicate between humans. Some application space associated with face and its expression includes personal identification and access management, video phone and group discussion, rhetorical application, human laptop application. Most of the countenance recognition strategies rumored thus far or specialize in expression class like happy, sad, fear, anger etc. For description of detail face countenance, Face Action writing (FACS) was style by Ekman. In FACS motion of muscles are divided into forty four action units and countenance are delineated by their combination. Synthesizing a facial image in model based mostly image secret writing and in MPEG-4 FAPs has vital clues in FACS. Victimizations MPEG-4 FAPs, totally different 3D face models will be animated. Moreover, MPEG-4 high level expression FAP permits invigorating numerous countenance intensities. However, the inverse drawback of extracting MPEG-4 low and high level FAPs from real pictures is far a lot of problematic attributable to the actual fact that the face could be an extremely deformable object. 2. LITERATURE SURVEY
Augmenting protein network embeddings with sequence information

Computational methods that infer the function of proteins are key to understanding life at the molecular level. In recent years, representation learning has emerged as a powerful paradigm to discover new patterns among entities as varied as images, words, speech, molecules. In typical representation learning, there is only one source of data or one level of abstraction at which the learned representation occurs. However, proteins can be described by their primary, secondary, tertiary, and quaternary structure or even as nodes in protein-protein interaction networks. Given that protein function is an emergent property of all these levels of interactions in this work, we learn joint representations from both amino acid sequence and multilayer networks representing tissue-specific protein-protein interactions. Using these hybrid representations, we show that simple machine learning models trained using these hybrid representations outperform existing network-based methods on the task of tissue-specific protein function prediction on 13 out of 13 tissues. Furthermore, these representations outperform existing ones by 14% on average.
Waste Plant Material as a Potential Adsorbent of a Selected Azo Dye

This paper discusses the adsorption of Direct Orange 26 azo dye on sunflower husk – an agricultural waste product. During the study, sorption kinetics and equilibrium as well as sorption capacity of the husk were investigated. The adsorption kinetics was analyzed using pseudo-first and pseudo-second order equations, which indicated a chemical sorption mechanism. The sorption equilibrium was approximated with the two-parameter Freundlich and Langmuir equations and the three-parameter Redlich-Peterson equation. The main experiments were carried out in a laboratory adsorption column under different process conditions. Experimental data were interpreted with the Thomas model, based on the volumetric flow rate, initial composition of the feed solution and mass of the adsorbent. The results of modeling the adsorption equilibrium, adsorption kinetics and adsorption dynamics were evaluated statistically.
The Analysis Of Methods Of Generating Accelerograms For Calculation Of Buildings

In the report the method of modeling artificial accelerograms earthquakes for concrete sites of buildings is presented. Accelerograms are calculated by means of the stochastic method developed for a dot seismic rupture. In calculations extent of the seismic rupture and local soil conditions was considered. The basic approach at the account of extent of the rupture is representation of a plane of rupture in the centre in the form of set of the subruptures of the smaller sizes. For each earthquake average spectra of fluctuations (accelerations and velocities). average spectra of reaction and average duration of strong movements (as duration of the fluctuations exceeding on amplitude level of 50 % of peak values) have been generated 25 synthetic accelerograms on which average values of the maximum accelerations were estimated. the maximum speeds.