Miracle-dz/UniFAR-FTUs huggingface dataset:
Radiation Null Compensation and Isolation Enhancement Between Two Orthogonal Magnetic Dipole Antennas

New approaches to tackle the radiation null and enhance the isolation between two magnetic dipole antennas are presented in this letter. By employing metal-via wall, the magnetic dipole and half-mode substrate-integrated waveguide (HMSIW) cavity are formed. Based on the orthogonal configuration of the magnetic dipoles, null compensation contributes to the nonblind point on the radiation pattern of the dipole. Furthermore, a defected surface structure is adopted to be inserted into the HMSIW cavity. The isolation enhancement with 42.6 dB between the antennas is achieved. With high isolation, the orthogonal integration of the magnetic dipoles is realized. The antenna is fabricated and measured to verify the proposed design.
Adición de un complejo enzimático en mezcla de sorgo con diferentes granulometrías: su efecto en la digestibilidad del nitrógeno y energía metabolizable de aves

Para evaluar el efecto de la adicion de un complejo enzimatico en una mezcla de sorgo en la digestibilidad verdadera del nitrogeno (DVN) y energia metabolizable (EMV) en gallos, se realizo un experimento con 56 gallos de la linea Bovans Brown. Se establecieron tres niveles de granulometria (G) para la mezcla de sorgo: 1, 3 y 5 mm. Se desarrollaron seis tratamientos: T1) mezcla de sorgo sin complejo enzimatico, + G1 mm; T2) mezcla de sorgo con complejo enzimatico + G1 mm; T3) mezcla de sorgo sin complejo enzimatico + G3 mm; T4) mezcla de sorgo con complejo enzimatico + G3 mm; T5) mezcla de sorgo sin complejo enzimatico + G5 mm y T6) mezcla de sorgo con complejo enzimatico + G5mm. Se aplico diseno completamente aleatorizado, con arreglo factorial 3 x 2 y ocho gallos (repeticion) por tratamiento. No se encontraron diferencias estadisticas para los factores granulometria y presencia o no del complejo enzimatico en la EMV (16.04 MJ/kg MS). Para la DVN, hubo interaccion en el complejo enzimatico y la granulametria (P < 0.001). El T4 tuvo la mayor digestibilidad (95.82 ± 1.66 %) y el T2 la menor (83.43 ± 2.71 %). Se concluye que la adicion del complejo enzimatico no afecta las variables evaluadas. Sin embargo, se recomiendan usar la mezcla de sorgo con granulometria de 3 mm, ya que se mantiene la EMV y aumenta la DVN.
Spacecraft Relative State Tracking Based on Genetic Algorithm-embedded Particle Filter

Spacecraft Relative State Tracking is not only the application foundation of space-based space surveillance system, but alsothe important prerequisite for space autonomous rendezvous and on-orbit servicing.Through making genetic algorithm (GA)embeddedPF resampling process, the particle degradation can be solved by using evolutionary thinking. Simulation result shows that GA-PF can achieve a good tracking for space target relative state.
DISE ~ NO DE UN OSCILADOR PARA RADIOFRECUENCIA INTEGRADO EN TECNOLOGIA CMOS

Este trabajo es un aporte en la construccion de una experiencia local alrededor del diseno de circuitos integrados. El diseno de un oscilador para radiofrecuencia, motiva el estudio detallado de algunas particularidades que lo ubiquen dentro de un sistema de comunicaciones integrado como un oscilador controlado por voltaje (VCO: Voltage Controlled Oscillator). A partir de las relaciones entre variables de diseno, se percibe el impacto de la caracteristica integrada del oscilador, involucrando la dependencia entre las dimensiones de los elementos con la aparicion de fenomenos parasitos, cuyo impacto se busca mitigar. Particularmente, se verifica el notable impacto del inductor integrado en la definicion del factor de calidad del circuito resonante, y asi, del desempeno del circuito. Una estrategia de diseno es propuesta, y se somete a las exigencias del estandar Bluetooth (frecuencia 2.402 GHz a 2.483 GHz, ruido de fase -128 dBc/Hz a 3 MHz de offset). El diseno realizado alcanza un ruido de fase de -128 dBc/Hz a 3 MHz de offset, con 22.33 mW de consumo de potencia. Adicionalmente, la posibilidad de integracion del oscilador disenado, mantiene presente el compromiso de considerar parametros de fabricacion a lo largo de toda la tarea de diseno. Se aplican los parametros de proceso de AMS (Austria Micro Systems) para tecnologia CMOS de 0.35? m. Se propone una disposicion de los elementos atendiendo criterios para la reduccion de mismatch, y se extrae el equivalente circuital del sistema integrado modelado, incluyendo las capacitancias parasitas debidas al proceso, arrojando -128 dBc/Hz a 3 MHz de offset de ruido de fase, con 30.25 mW de consumo de potencia.
Transmission multimedia fiable sur internet

La transmission de flot multimedia sur internet est maintenant une realite qui est deja implantes dans nos micro-ordinateurs. Neanmoins, la reception des flots multimedia avec un niveau de qualite agreable a l'utilisateur final, necessite la validation de contraintes particulieres, qui forment un nouveau defi pour les reseaux. L'internet est un reseau qui assure la transmission de donnees sans aucune garantie de qualite. Le reseau transmet les paquets qui lui sont soumis au mieux sans aucune limite de delai de transmission, ni aucune garantie de reception. La transmission sur reseau reste un probleme de communication et il existe un cadre general d'etude des systemes de communication : la theorie de l'information. Notre ambition est de recentrer la problematique de la transmission d'information sur les reseaux dans le cadre plus general de la theorie des communications. La theorie de l'information permet de determiner l'espace des debits accessibles suivant les differents modeles de canal utilises. Nous etendons aux canaux reseaux (point a point et multicast) les resultats de la theorie de l'information (capacite, bornes de codages,). Nous presentons des schemas de codage applicable en pratique qui permettent de compenser les pertes subites par la transmission. Nous nous interessons ensuite au codage prioritaire. Dans cette approche certaines parties du flot transmis sont plus protegees que d'autres. Nous montrons la relation intrinseque de cette approche avec le codage adapte a l'emission sur un canal multicast. Nous remettons en cause la separation du codage source et canal, car elle ne permet d'acceder a des performances optimales. Nous analysons le codage conjoint source/canal dans le cadre de la transmission multimedia sur internet. Un mecanisme d'optimisation conjointe des parametres du codage source et du codage canal est applique qui permet de minimiser la distorsion moyenne observe a la reception tout en bornant la probabilite que cette distorsion soit superieure a un seuil. Une procedure d'adaptation de l'application au reseau qui utilise ce modele est proposee.
Optimisation de la modélisation des régimes de fonctionnement des garnitures mécaniques d'étanchéité : analyse théorique et expérimentale

Les garnitures mecaniques sont des composants d'etancheite d'arbres tournants. Elles sont constituees de deux surfaces planes annulaires dont le contact est lubrifie par le fluide a etancher.L'operation de recherche « Jointlub » du departement D3 de l'institut P' a developpe des outils de simulation du comportement des garnitures par des methodes analytiques, semi analytiques et numeriques. En s'appuyant sur ces acquis, l'objectif de cette these vise a definir une methodologie d'analyse prealable permettant l'optimisation de la modelisation du fonctionnement d'une garniture mecanique en fonction de la solution technologique choisie. Ceci consiste a proposer un procede de choix d'outils de modelisation parmi les principaux types existants.Un ensemble d'indicateurs et de criteres est developpe afin de determiner les phenomenes physiques preponderants lors du fonctionnement d'une garniture dans des conditions donnees. Le modele retenu pour la simulation devra prendre en compte les phenomenes identifies.Des validations experimentales ont ete realisees pour une garniture mecanique operant dans differents regimes de fonctionnement. Une etude de l'evolution de la topographie des faces de frottement, du couple de frottement, du debit de fuite et du comportement thermique ont ete effectues. Les experiences ont montre que le comportement des garnitures depend fortement du regime de lubrification : mixte, hydrodynamique ou thermo-elasto-hydrodynamique.Les modeles theoriques ont ete compares aux resultats experimentaux. Une bonne correlation est obtenue dans leur domaine de validite, defini a partir des indicateurs. Des ecarts plus importants sont observes lorsque les modeles sont utilises dans des zones ou ils ne prennent pas en compte l'ensemble des phenomenes physiques. Cette comparaison a montre que les indicateurs et criteres de la methode de choix proposee sont pertinents et permettent une bonne identification des phenomenes physiques a prendre en compte.
Glomerular Density-Associated Changes in Clinicopathological Features of Minimal Change Nephrotic Syndrome in Adults

Background: Differences in nephron number and/or glomerular size between individuals, in relation to intrauterine growth retardation or low birth weight, have been suggested to affect the clinical course of minimal change nephrotic syndrome (MCNS) in children. However, no previous study has investigated the potential influences of these histological variables on the clinical course of adult patients with MCNS. Methods: The glomerular density (GD; the number of non-sclerotic glomeruli per renal cortical area) and the glomerular volume (GV) were evaluated using renal biopsy specimens from adult patients with a histological diagnosis of MCNS (n = 50). Relationships between these variables and clinicopathological features, including the initial response to corticosteroid therapy, were analyzed. Results: Both the GD (1.5–6.5/mm2) and the GV (1.2–4.4 × 106 µm3) showed about 4-fold variations, and a close inverse correlation was observed between these two variables. Notably, the MCNS patients with a low GD showed a trend towards having similar clinicopathological characteristics as patients with a histological diagnosis of focal segmental glomerular sclerosis, as compared to the MCNS patients with a high GD. In addition, during the initial treatment with corticosteroids, the number of patients achieving complete remission was significantly lower in the MCNS patients with a low GD than that in the MCNS patients with a high GD. Conclusion: These results suggest that the GD in renal biopsies may be an important determinant of the glomerular size variability, and can therefore influence the clinical phenotype, such as the response to corticosteroid therapy, in adult patients with MCNS.
A porohyperelastic finite element model of the eye: the influence of stiffness and permeability on intraocular pressure and optic nerve head biomechanics

Progressively deteriorating visual field is a characteristic feature of primary open-angle glaucoma (POAG), and the biomechanics of optic nerve head (ONH) is believed to be important in its onset. We used porohyperelasticity to model the complex porous behavior of ocular tissues to better understand the effect variations in ocular material properties can have on ONH biomechanics. An axisymmetric model of the human eye was constructed to parametrically study how changes in the permeabilities of retina–Bruch's–choroid complex , sclera , uveoscleral pathway , and trabecular meshwork as well as how changes in the stiffness of the lamina cribrosa (LC) and sclera affect IOP, LC strains, and translaminar interstitial pressure gradients (TLIPG). Decreasing from 5 × 10− 12 to 5 × 10− 13 m/s increased IOP and LC strains by 17%, and TLIPG by 21%. LC strains increased by 13% and 9% when the scleral and LC moduli were decreased by 48% and 50%, respectively. In addition to the trabecular meshwork and uveoscleral pathway, the retina–Bruch's–choroid complex had an important effect on IOP, LC strains, and TLIPG. Changes in and scleral modulus resulted in nonlinear changes in the IOP, and LC strains especially at the lowest and . This study demonstrates that porohyperelastic modeling provides a novel method for computationally studying the biomechanical environment of the ONH. Porohyperelastic simulations of ocular tissues may help provide further insight into the complex biomechanical environment of posterior ocular tissues in POAG.
Using Local Grammar for Entity Extraction from Clinical Reports

Information Extraction (IE) is a natural language processing (NLP) task whose aim is to analyze texts written in natural language to extract structured and useful information such as named entities and semantic relations linking these entities. Information extraction is an important task for many applications such as bio-medical literature mining, customer care, community websites, and personal information management. The increasing information available in patient clinical reports is difficult to access. As it is often in an unstructured text form, doctors need tools to enable them access to this information and the ability to search it. Hence, a system for extracting this information in a structured form can benefits healthcare professionals. The work presented in this paper uses a local grammar approach to extract medical named entities from French patient clinical reports. Experimental results show that the proposed approach achieved an F-Measure of 90. 06%.
A 0.5-V 0.4–2.24-GHz Inductorless Phase-Locked Loop in a System-on-Chip

A phase-locked loop (PLL) is proposed for low-voltage applications. A new charge pump (CP) circuit, using gate switches affords low leakage current and high speed operation. A low-voltage voltage-controlled oscillator (LV-VCO) composed of 4-stage delay cells and a low-voltage segmented current mirror (LV-SCM) achieves low voltage-controlled oscillator gain (KVCO), a wide tuning range, and good linearity. A LV-SCM generates more current with small area by switching the body rather than the gate. The PLL is implemented in standard 90-nm CMOS with regular VT (RVT) devices. Its output jitter is 2.22 ps (rms), which is less than 0.5% of the output period. The phase noise is - 87 dBc/Hz at 1-MHz offset from a 2.24-GHz center frequency. Total power dissipation at 2.24-GHz output frequency, and with 0.5-V power supply is 2.08 mW (excluding the buffers). The core area is 0.074 mm2.
WHO Multicenter Evaluation of FACSCount CD4 and Pima CD4 T-Cell Count Systems: Instrument Performance and Misclassification of HIV-Infected Patients

Background:CD4+ T-cell counts are used to screen and follow-up HIV-infected patients during treatment. As part of the World Health Organization prequalification program of diagnostics, we conducted an independent multicenter evaluation of the FACSCount CD4 and the Pima CD4, using the FACSCalibur as reference method. Methods:A total of 440 paired capillary and venous blood samples were collected from HIV-infected patients attending the HIV outpatient clinic in Antwerp, Belgium, and the HIV care and treatment center in Dar es Salam, Tanzania. Capillary blood was run on Pima analyzer, whereas venous blood was analyzed on FACSCount, Pima, and FACSCalibur instruments. Precision and agreement between methods were assessed. Results:The FACSCount CD4 results were in agreement with the FACSCalibur results with relative bias of 0.4% and 3.1% on absolute CD4 counts and an absolute bias of −0.6% and −1.1% on CD4% in Antwerp and Dar es Salam, respectively. The Pima CD4 results were in agreement with the FACSCalibur results with relative bias of −4.1% and −9.4% using venous blood and of −9.5% and −0.9% using capillary blood in Antwerp and Dar es Salam, respectively. At the threshold of 350 cells per microliter, the FACSCount CD4 and Pima CD4 using venous and capillary blood misclassified 7%, 9%, and 13% of patients, respectively. Conclusions:The FACSCount CD4 provides reliable CD4 counts and CD4% and is suitable for monitoring adult and pediatric HIV patients in moderate-volume settings. The Pima CD4 is more suitable for screening eligible adult HIV patients for antiretroviral treatment initiation in low-volume laboratories.
[Modulation of the anti-tumor effect of BRM under various nutritional or endocrine conditions].

Immuno-chemotherapeutic effects on the growth of MM-48 mammary tumor were studied in syngeneic C3H/He mice fed diets containing a low (D), normal (N) or arginine-supplemented (NA) protein content. The serum protein levels were 5.7 g/dl in N-mice and 3.7 g/dl in D-mice, respectively. On the other hand, no difference was seen between the two groups, with regard to intra-tumoral protein concentrations. The natural killer (NK) activity of spleen cells was significantly lower in D-mice than in N-or NA-mice. Augmentation of NK activity was detected following the i.p. injection of OK-432 or LENTINAN, while no augmentation was recognized in D-mice. Interferon production of cultured spleen cells was significantly reduced in D-mice, and significantly increased in NA-mice compared with N-mice. NK activity was markedly augmented at 7 days after bilateral oophorectomy in N-mice. Both NK and IFN titers were significantly reduced following administration of estradiol every 7 days. The growth of MM-48 tumor was inhibited by daily administration of OK-432 or LENTINAN in N-mice. However, the tumor growth was paradoxically accelerated after administration of the same drugs in D-mice. These findings indicated that the nutritional or endocrine environment of cancer-bearing mice plays an important role in the effect of some kinds of BRMs. A clinical randomized study of advanced and recurrent gastric cancer patients treated with MMC and FT (MF) with or without LENTINAN, was then performed. We recognized excellent end-point results only in LENTINAN-administered patients with normal protein levels, while no effect of LENTINAN was seen in patients with low protein levels (below 6.0 g/dl).
Effects of Social Relationships on Mortality among the Elderly in a Japanese Rural Area: An 88-month Follow-up Study

BACKGROUND: The association between social relationships and lower mortality has been well documented in Western countries. This study aims to investigate that association among elderly Japanese in a rural area. METHODS: An analysis was conducted with 1,994 subjects (58.1% women), 78.3% of the total elderly aged 65 and older in a town, who were independent in activities of daily living. A baseline survey was carried out in 1992, and subjects were followed until 1999. Cox proportional hazard models examined the association between social relationships (availability of casual friend/ support provider, group membership, job, living arrangement) and an 88-month mortality. RESULTS: A significant association between social relationships and mortality was observed among the old-old (aged 75 and older). Among men, having a job and group membership were significantly associated with lower mortality with hazard ratios (95% confidence intervals) of 0.62 (0.41-0.94) and 0.60 (0.40-0.90), respectively, after adjustment for age, diagnosed illnesses, self-rated health, other social relationships, annual income, and home ownership. Among women, having a job and living alone were significantly associated with lower mortality with hazard ratios (95% confidence intervals) of 0.67 (0.45-0.99) and 0.35 (0.13-0.97), respectively. CONCLUSIONS: Social relationships such as having a job and group membership were associated with lower mortality among the old-old. In addition, old-old women living alone were better off in terms of mortality after adjustment for possible confounders. This suggests the importance of considering family relationships in terms of quality in areas where multi-generation households prevail.
Hippocampal function during behaviorally silent associative learning: Dissociation of memory storage and expression

In laboratory studies, the assessment of memory is typically associated with overt behavioral responses. Thus, it has been difficult to determine whether the enhancement of hippocampal sensory‐evoked potentials that often accompany memory formation are the neurophysiological manifestation of a memory “trace” or are a secondary product of the behavioral expression of the memory. We addressed this issue by examining changes in evoked hippocampal field potentials during sensory preconditioning, a form of behaviorally silent relational learning that requires an intact hippocampus for execution. Rats were exposed to presentations of a white noise (S1) that terminated with a tone (S2). These pairings of ostensibly “neutral” stimuli supported no change in the behavior elicited by the noise. However, if the tone was subsequently paired with mild footshock (US), suppression of ongoing licking behavior (indicative of fear) was elicited by the noise, indicating that the animal had associated the noise with tone (S1‐S2), and had represented the noise‐tone‐shock (S1‐S2‐US) relationship. Pre‐training neurotoxic lesions of the hippocampus had no effect on conditioned suppression to tone after tone‐shock (S2‐US) pairings, but disrupted the expression of continued suppression to noise (S1) after tone‐shock pairings. In a second experiment, sensory‐evoked field potentials in the dorsal hippocampus were recorded with extracellular electrodes. No changes in the hippocampal response evoked by white noise were observed after pairings of noise and tone, i.e., no evidence for a memory trace could be detected. In contrast, after tone was paired with footshock, two short‐latency negative potentials within the noise‐evoked field response increased in amplitude, a response often presumed to reflect a neurophysiological correlate of memory storage. In total, these results suggest that although the hippocampus critically contributes to the processing of a behaviorally silent associative memory, there may be no role for changes in the amplitude of hippocampal sensory‐evoked field potentials in storing representations of the relationships between sensory experiences. Hippocampus 2002;12:648–656. © 2002 Wiley‐Liss, Inc.
Schistosome hemoglobin protease; search for inhibitors.

Four-hundred and 20 chemical compounds including 387 organic compounds (representing 216 structural types), 27 classical enzyme inhibitors, 4 antischistosome drugs, and 2 highly specific en- zyme inhibitors (for trypsin and chymotrypsin) were tested for inhibitory activity against (Schistosoma mansoni) schistosome hemoglobin protease (SHP). Six organic compounds and 4 classical enzyme inhib- itors inhibited, to a varying degree, the activity of SHP at 1 X 10-5 M; the inhibitor specific for trypsin, N-a-Tosyl L-Lysyl Chloromethane hydrochloride, was also active, but the chymotrypsin-specific inhibitor, N-Tosyl-L-Phenylalanyl Chloromethane, was not.
The fine structure of the neuromuscular junction of the frog

In recent years fairly detailed information has been obtained on the physiological events which occur at the vertebrate neuromuscular junction. Experiments on frog and mammalian muscle have shown that the transmitter, acetylcholine, is released from the axon terminals in discrete multi-molecular packets, and attention has been directed to the presence of submicroscopic 'vesicles' inside the nerve endings and their possible significance in the quantal distribution of the transmitter agent (de Robertis & Bennett, 1954, 1955; del Castillo & Katz, 1956; Robertson, 1956b; Palay, 1956; de Robertis, 1958; Reger, 1958; Katz, 1958). The purpose of the present work was to examine in more detail the submicroscopic structure of the myoneural junction in the frog from which the greater part of the physiological evidence had been derived. The basic information on the structure of this synapse is already available, as a result of the remarkable microscopic and histochemical studies of Couteaux (1947, 1955, 1958).