Miracle-dz/UniFAR-FTUs huggingface dataset:
MESURES RÉPÉTÉES DE LA PERMÉABILITÉ CAPILLARO-ALVÉOLAIRE A UNE MACROMOLÉCULE AU COURS DE MODÈLES DE LÉSION PULMONAIRE INFLAMMATOIRE CHEZ LE CHIEN

Nous avons mis au point une methode de lavage broncho-alveolaire permettant d'effectuer des mesures repetees (toutes les 15 min. pendant 3h30.) de la permeabilite capillaro-alveolaire a une macromolecule (FITC-dextran). Apres une lesion a l'acide oleique (AO) on observe, en 30 minutes un pic de permeabilite au FITC-dextran. La permeabilite decroit ensuite lentement jusqu'a la fin de l'experience. Nous avons teste les effets de la terbutaline, un β2-agoniste repute reduire in vitro l'augmentation de permeabilite dans les lesions pulmonaires inflammatoires. Une perfusion de terbutaline debutee 10 min. apres la lesion a l'AO ne modifie pas l'evolution de la permeabilite. Une perfusion tardive de terbutaline (90 min. apres la lesion) aggrave la permeabilite. Comme l'index cardiaque et la pression capillaire augmentent au cours de la perfusion de terbutaline, nous supposons que la terbutaline recrute des capillaires leses et aggrave la permeabilite a la phase tardive de la lesion a l'AO.
New horizons on stingless beekeeping (apidae, Meliponini).

A criacao de abelhas sem ferrao, ou meliponicultura, e uma atividade antiga, especialmente nos Neotropicos. Atualmente, especialmente no Brasil, ela experimenta um novo florescimento, sendo amplamente praticada em varias regioes, pela criacao de diversas especies. Isso tem sido possivel por avancos no conhecimento de sua biologia basica, assim como em seu manejo. Neste artigo e apresentado um panorama dos avancos alcancados, especialmente no estado do Para, pelo grupo de pesquisa em abelhas da Embrapa Amazonia Oriental e da Universidade Federal do Para. Focou-se nos avancos alcancados com as tecnicas de manejo de ninhos, o armazenamento e processamento de mel e a suplementacao alimentar para as colonias, alem de apontar questoes especificas que ainda devem ser tratadas para se alcancar uma meliponicultura sustentavel.
A quantum approach to the hidden subgroup problem using group representations and automorphisms

The hidden subgroup problem is a fundamental problem in quantum computation. It has many interesting instances for which we do not yet have an efficient classical algorithm and want to find or have found an efficient quantum algorithm. Examples of such instances are the discrete logarithm problem, prime factorization and the graph isomorphism problem. In this thesis we take a quantum computational approach to the hidden subgroup problem. We discuss an efficient algorithm for instances of the hidden subgroup problem in abelian groups stated in [4] and apply this algorithm to the discrete logarithm problem. There is no uniform algorithm for the non-abelian case yet. We discuss the approach taken by [4] which considers what happens when we apply the algorithm for the non-abelian case to the abelian case. By doing so, it turns out that we will be able to determine the part of the hidden subgroup that is invariant under conjugation, but we won’t be able to efficiently solve the graph isomorphism problem. Although the nonabelian case of the hidden subgroup problem remains open, we will discuss the approach taken by [5] which shows that in extraspecial groups, a class of almost abelian groups, one can solve the hidden subgroup problem efficiently by exploiting clever automorphisms. Title: A quantum approach to the hidden subgroup problem using group representations and automorphisms Authors: Casper Gyurik, casper.gyurik@student.uva.nl, 10334149 Supervisor: prof. dr. Buhrman and prof. dr. Opdam Date: July 15, 2015 Korteweg-De Vries Institute for Mathematics University of Amsterdam Science Park 904, 1098 XH Amsterdam http://www.science. uva.nl/math
Less IS More: some thoughts on the Tolerance Principle in the context of the Maximise Minimal Means model

Recent work by Charles Yang seeks to probe the question of the circumstances under which humans form linguistic generalisations about the structure of the language input to which they are exposed. Yang (2016) presents an extended argument for the so-called Tolerance Principle (TP), a simplied version of which is given in (1) (see Yang 2016, 2018a/in press, 2018b) for discussion of the harmlessness of the simplication, and Yang (2016) for detailed motivation of the non-simplied form):
Experiments on rapidly rotating turbulent flows

• A submitted manuscript is the version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers. Link to publication
Effect of Ulex europaeus L. extracts on polyphenol concentration in Capsicum annuum L. and Lactuca sativa L.

In this work, the effect of aqueous and methanolic extracts from roots and shoots of Ulex europaeus L. on the total polyphenol content of Capsicum annuum L. and Lactuca sativa L. grown in laboratory and greenhouse conditions was evaluated. Treatments consisted of U. europaeus L. extracts (20, 40, 80, 160 and 320 mg kg-1) as well as caffeine and distilled water as controls, all of which were applied with a manual sprayer on seedlings of the aforementioned species. Total polyphenols were determined using the Folin-Ciocalteu method. Under control conditions, the polyphenol concentration in C. annuum was lower in laboratory than in greenhouse conditions (P<0.05). Conversely, L. sativa had a higher polyphenol concentration in the laboratory than in the greenhouse (P<0.05). Also, under laboratory conditions the polyphenol content rose with increasing extract doses in both species, but this tendency was not observed in the greenhouse. Finally, different doses of extracts of U. europaeus L. affect total polyphenol content in both species. This effect is clear under laboratory conditions, but not in greenhouse experiments. These findings open up the possibility of cultivating species with higher antioxidant contents using natural products.
El devenir del sistema universitario público en la Argentina a través de sus olas expansivas: Diferenciación en la formación de fuerza de trabajo y acumulación de capital (1971-2015)

Over the last five decades, the university system underwent three attempts at reform aimed at improving its performance and transforming some of its characteristics. However, although these processes resulted in a quantitative expansion of the number of institutions, they did not achieve overall qualitative changes. In this paper, we aim to analyze the content of these processes in relation to the specific character of capital accumulation in Argentina. Our hypothesis is that, on the one hand, the process of capital accumulation requires that only a small fraction of workers expand their productive attributes to a range that corresponds to the completion of a university degree, while it is enough for another major fraction to make a partial advance in their careers. And, on the other hand, the consolidation of a large mass of surplus population in recent decades resulted in capital no longer requiring the same range of development of productive attributes from the generality of individuals who completed the secondary education, which was expressed in the degradation of part of that cycle. This process, however, has advanced to such an extent that the training of workers with non-degraded productive attributes does not cover the existing demand for them. Therefore, the university system also began to play the role of allowing a fraction of this population to reach or surpass this development.
Rotation periods from the inflection point in the power spectrum of stellar brightness variations: II. The Sun

Young and active stars generally have regular, almost sinusoidal, patterns of variability attributed to their rotation, while the majority of older and less active stars, including the Sun, have more complex and non-regular light-curves which do not have clear rotational-modulation signals. Consequently, the rotation periods have been successfully determined only for a small fraction of the Sun-like stars observed by transit-based planet-hunting missions, such as CoRoT, Kepler, and TESS. This suggests that only a small fraction of such systems have been properly identified as solar-like analogs. We apply a new method for determining rotation periods of low-activity stars, like the Sun. The method is based on calculating the gradient of the power spectrum (GPS) of stellar brightness variations and identifying a tell-tale inflection point in the spectrum. The rotation frequency is then proportional to the frequency of that inflection point. In this paper test this GPS method against available photometric records of the Sun. We apply GPS, autocorrelation functions, Lomb-Scargle periodograms, and wavelet analyses to the total solar irradiance (TSI) time series obtained from the Total Irradiance Monitor (TIM) on the Solar Radiation and Climate Experiment (SORCE) and the Variability of solar IRradiance and Gravity Oscillations (VIRGO) experiment on the SOlar and Heliospheric Observatory (SoHO) missions. We analyse the performance of all methods at various levels of solar activity. We show that the GPS method returns accurate values of solar rotation independently of the level of solar activity. In particular, it performs well during periods of high solar activity, when TSI variability displays an irregular pattern and other methods fail. Our results suggest that the GPS method can successfully determine the rotational periods of stars with both regular and non-regular light-curves.
Inflammatory mechanisms in bacterial infections: focus on mast cells and mastitis

Inflammation is an unspecific response of the immune system to pathogens, for example, invasion by bacteria. This thesis focuses on two aspects of inflammation in the context of bacterial infections: (1) mast cells and (2) mastitis. Mast cells are potent proinflammatory leucocytes that have been implicated in the defence against bacterial infections. Mastitis is an inflammation of the mammary tissue and is one of the most economically destructive disease in the dairy industry worldwide. Here, mast cell synthesis of the potent pro-angiogenic vascular endothelial growth factor (VEGF) in response to stimuli with Staphylococcus aureus (S. aureus) was studied using an in vitro model of primary mouse mast cells. VEGF synthesis was found to be dependent on the presence of live whole bacteria. Previous in vivo investigations of the roles of mast cells in bacterial infections have been conducted using c-Kit-dependent mast cell-deficient mice. These mice suffer from numerous abnormalities in addition to the lack of mast cells. Instead, we used newer, cKit-independent mast cell-deficient mice (Mcpt5-Cre), which have fewer non-mast cell related abnormalities. We found no impact of the mast cell deficiency on the course of intraperitoneal S. aureus infection (e.g., bacterial clearance and cytokine production). We differentiated the virulence of, and response to, a set of clinical bacterial strains of bovine mastitis origin. Escherichia coli (E. coli) and S. aureus strains were injected intraperitoneally into mice. One E. coli strain(strain 127) was found to consistently cause more severe infection (judged by a clinical score) and induce a distinct profile of cytokines (CXCL1, G-CSF, CCL2). The concentrations of these cytokines correlated with both the clinical score and bacterial burden. The kinetics of the clinical and molecular changes that occurred during acute bovine mastitis were studied using a bovine in vivo model in which mastitis was induced by an intramammary infusion of E. coli lipopolysaccharide. Changes in clinical parameters (clinical score, milk changes, rectal temperature) as well as in milk and plasma cytokine concentrations and changes in the metabolome were registered. The progression of these changes occurred in the following order: (1) signs of inflammation in the udder and an increase in milk cytokine concentrations (after/at two hours), (2) visible changes in the milk and an increase in milk somatic cell counts (SCCs) (four hours), (3) changes in the plasma metabolome(four hours) and (4) changes in the milk metabolome (24 hours).
Insects: The Disregarded Domestication Histories

Domestication has irrevocably impacted human evolution. The domestication process/ pathways have been the focus of abundant research for plants and vertebrates. Advances in genetics and archeology have allowed tremendous progresses in the understanding of domestication for these organisms. In contrast, insects’ domestication has comparatively received far less attention to date. Yet, insects are the most common animal group on Earth and provide many valuable ecosystem services to humans. Therefore, the aims of this chapter are (i) to provide an overview of main ancient and recent insect domestica- tion histories and (ii) to reread them by the light of the domestication process, pathways, triggers, and consequences observed in other animal species. Some of the considered species (i.e., silkworm and honey bee) have been chosen because they are among the few insects commonly acknowledged as domesticated, while others allow illustrating alter- native domestication patterns. The overview of current literature shows similar human-directed pathway and domestication syndrome (e.g., increased tameness, decreased aggressiveness, modified reproduction) between several insect species.
Rationalizing phonon dispersion for lattice thermal conductivity of solids

Lattice thermal conductivity (κL) is one of the most fundamental properties of solids. The acoustic–elastic-wave assumption, proposed by Debye (Debye P. Ann Phys 1912; 344: 789–839), has led to linear phonon dispersion being the most common approximation for understanding phonon transport over the past century. Such an assumption does not take into account the effect of a periodic boundary condition on the phonon dispersion, originating from the nature of periodicity on atomic arrangements. Driven by modern demands on the thermal functionality of materials, with κL ranging from ultra-low to ultra-high, any deviation from the Debye approximation in real materials becomes more and more significant. This work takes into account the periodic boundary condition, and therefore rationalizes the phonon dispersion to be more realistic. This significantly improves the precision for quickly predicting κL without any fitting parameters, as demonstrated in hundreds of materials, and offers a theoretical basis rationalizing κL to be lower than the minimum currently accepted based on the Debye dispersion. This work paves the way for designing solids with expected κL and particularly inspires the advancement of low-κL materials for thermal energy applications.
Collaborative Deep Denoising Autoencoder Framework for Recommendations

This work proposes a Collaborative Deep Denoising Autoencoder (CDDAE) framework for recommender systems to improve recommendation experiences. In this framework, a non-linear matrix factorization is computed through deep denoising autoencoder leveraging user-item interactions and auxiliary profile information. Different from existing matrix factorization and deep learning approaches, this framework combines autoencoder, collaborative filtering and embedded auxiliary information together to provide better recommendation experiences. Experiments conducted show CDDAE improves recommendation experiences by 5.6% in precision and 7.4% in recall averagely.
Prediction and control of symmetry breaking in embryoid bodies by environment and signal integration

ABSTRACT During early embryogenesis, mechanical constraints and localized biochemical signals co-occur around anteroposterior axis determination and symmetry breaking. Their relative roles, however, are hard to tease apart in vivo. Using brachyury (Bra), a primitive streak and mesendoderm marker in mouse embryoid bodies (EBs), we studied how contact, biochemical cues and neighboring cell cues affect the positioning of a primitive streak-like locus and thus determine the anteroposterior axis. We show that a Bra-competent layer must be formed in the EB before Bra expression initiates, and that Bra onset locus position is biased by contact points of the EB with its surrounding, probably through modulation of chemical cues rather than by mechanical signaling. We can push or pull Bra onset away from contact points by introducing a separate localized Wnt signal source, or maneuver Bra onset to a few loci or to an isotropic peripheral pattern. Furthermore, we show that Foxa2-positive cells are predictive of the future location of Bra onset, demonstrating an earlier symmetry-breaking event. Our analysis of factors affecting symmetry breaking and spatial fate choice during this developmental process could prove valuable for in vitro differentiation and organoid formation. Summary: Contact with surfaces and localized Wnt sources can direct the site of brachyury expression onset in mouse embryoid bodies, breaking its initial symmetry.
Polyethylene glycol damages grafted citrus plants based on biometric, physiological,and biochemical responses

1Agronomist, graduate student in Crop Science University of São Paulo, Piracicaba-SP, Brazil. Email: eduardo.girardi@embrapa.br. 2Biologist, graduate student at University of São Paulo, São Paulo-SP, Brazil.Email: brandao.a. d@bol.com. br 3Agronomist, professor at the University of São Paulo, Piracicaba-SP, Brazil. Emails: rdcoelho@usp.br, htzcouto@usp.br; francisco.mourao@ usp.br 4Biologist, professor at the University of São Paulo, São Paulo-SP, Brazil. Email: msbuck@usp.br Abstract – Drought tolerance is a major trait for the selection of citrus rootstocks in breeding programs. PEG 4000 solution at 110 g L-1 (osmotic potential of -376 kPa) was used to evaluate biometric, physiological, and biochemical responses of grafted citrus plants in pots. ‘Valencia’ sweet orange plants grafted onto ‘Rangpur’ lime (drought tolerant) rootstock showed greater plant growth compared to that on ‘Swingle’ citrumelo (drought sensitive) rootstock, regardless of PEG-induced stress; however, biological responses to PEG were similar on both rootstocks. Plant dry weight, gas exchange, and leaf and root starch concentrations were reduced by PEG. Water potential at 2:00 p.m. and Fe and Mn leaf concentrations increased with severe phytotoxic symptoms. The results corroborate the limitation of PEG for assessing drought tolerance of citrus plants at the whole plant level.
Characterising Land Cover Change in Brunei Darussalam’s Capital District

In fast-developing regions like Southeast Asia monitoring urban areas presents a challenge given the lack of publicly available data. This is an issue that precludes the nuances of a city’s growth and undermines the way land use is considered with respect to planning. The issue of data availability is very much present in the small nation of Brunei. Little is still known about the spatiotemporal evolution of its urban realm in particular, with regard to its national development planning. The country presents an interesting case-study given the pursuit of two highly opposing master-plans within the last 40 years. Its first master plan advocated polycentric growth away from the capital city, Bandar Seri Begawan. Its latest plan, however, currently promotes compact growth within a predefined urban footprint as a development control mechanism. This paper looks at remotely-sensed satellite data to examine the way in which the two implemented master-plan strategies have translated into actual land-use thus far. It employs a supervised classification procedure and characterises urban land into three typologies: urban infill, edge growth, and leapfrog growth. The paper’s findings suggest that residential developments play a stronger role in driving urban growth in Brunei. This is particularly true for public housing, which has typically persisted in isolated pockets of low density at the city fringe. This study has produced a novel dataset of urban land use and land cover in Brunei; and, its quantification may prove useful in understanding the impacts of master planning and the formulation of development policies both within Brunei, and the wider Southeast Asian region.
Yolk sac and its effects on fetal prognosis

Background: The yolk sac is the first extra embryonic structure that becomes sonographically visible within the gestational sac. It provides nutritional, metabolic, endocrine, immunologic, and hematopoietic functions during organogenesis in embryonic life, before placental circulation is established. Spontaneous abortion rates are significantly elevated where the yolk sac volume falls outside the 5th to 95th percentile. Abnormal morphological appearance of the yolk sac is also suggestive of serious growth disorders of the fetus. The aim is to find out the predictive value of yolk sac on outcome of the pregnancy and any probable relationship of the yolk sac pattern with the gender of the fetus.Methods: The present study was carried out on fifty patients in their first trimester of pregnancy. Patients were divided into their respective gestational age groups and according to the morphology of the yolk sac. Data were compared using Chi square test. p value less than 0.5 was considered significant.Results: Out of the fifty patients, twenty-nine were having regular yolk sac, eleven were with irregular yolk sac and ten were with hyperechoic yolk sac. There was a significant number of fetal demise in the cases with hyperechoic and irregular yolk sac. Also, there were hardly any live births in the few cases in which the yolk sac was either too small or too big.Conclusions: The present study concludes that along with a yolk sac of a given normal range for its size, it should also be of normal morphology for better prognosis of the pregnancy. Also, the increase in the number of female live births needs further studies as to whether there is any abnormality in the Y chromosome causing morphologically abnormal yolk sac and subsequent fetal demise.
POST-CRACKING BEHAVIOUR OF BASALT FIBRE REINFORCED CONCRETE

The post-cracking softening behaviour of concrete with basalt fibres (BFs) has been investigated. The flexural load-CMOD and load-deflection relationships, obtained in threepoint bending test, have been used to determine the fracture parameters: fracture energy, critical stress intensity factor, crack tip opening displacement, critical effective crack length. The flexural toughness of concrete was found to increase considerably when fibres were used. The changes were observed in both pre-peak and post-peak behaviour of concrete specimens. The application of the basalt fibres lead to the enhancement in fracture parameters, however the fibres slightly influence the mechanical parameters e.g. compressive strength and modulus of elasticity.