Miracle-dz/UniFAR-FTUs huggingface dataset:
Preparation of polyamide 6/copper nanocomposites and its properties

Polyamide 6/copper (noted as PA6/Cu) nanocomposites was prepared readily where CuO was used as the filler and adipic acid as the catalyst. CuO was reduced to Cu elemental as well as dispersed in the polymerization system of PA6 via using the reducing atmosphere of the polymerization process. As-prepared PA6/Cu nanocomposites were characterized by means of differential scanning calorimetry (DSC), X-ray diffraction (XRD), ultraviolet-visible absorption spectroscopy (UV) and transmission electron microscopy (TEM). Results showed that CuO was reduced to Cu elemental, and evenly dispersed in PA6 matrix. The melting temperature of PA6 matrix material improved with increasing the content of Cu in comparison with pure PA6, however, the crystallization temperature tended to the low temperature. The crystal structure of PA6/Cu nanocomposites tended to generate γ crystal shape. Additionally, the size of as-fabricated nanoparticle was about 30-50 nm, and the ultraviolet absorption of 360 nm represented the absorption of Cu nanoparticles. The mechanical properties and friction behaviors of PA6/Cu nanocomposites were evaluated by means of universal tensile testing machine, impact testing machine, and friction testing machine. Results showed that as-prepared composites with 0.3% nano-Cu content possessed the best tensile strength of 27.75 MPa, as increased by 29.1% in comparison that of PA6. Furthermore, the impact toughness of PA6/Cu nanocomposites with nano-Cu content of 0.7% reached to 7.20 MPa, as increased by 170.5%. Friction coefficient and grinding spot diameter presented a decreasing tendency with increasing the nano-Cu content.
Physico‐chemical and nutritional characteristics of einkorn flour cookies

Einkorn (Triticum monococcum L.) is a diploid wheat whose kernels are rich in proteins, carotenoids, tocols, phenolic acids, and trace minerals. Our research analyzed the physico‐chemical and nutritional characteristics of einkorn cookies prepared from refined flour of two einkorns (ID1395 and Monlis) and one common wheat (Blasco). The traits analyzed were color, size, and surface texture (Image Analysis); inner texture (Bending and Penetration tests); carotenoids and tocols content and composition; furosine, glucosylisomaltol, and hydroxymethylfurfural as heat damage indices (HPLC). Einkorn cookies were thinner, larger, slightly darker, with smoother surface, and higher breaking resistance than the control cookies. Furthermore, they had more carotenoids (5.0 vs. 2.2 mg/kg DM) and showed less heat damage (188.5 vs. 242.4 mg furosine/100 g protein) than common wheat cookies. Room‐temperature storage under dark in sealed plastic containers led to a decrease in lutein (8%–17%) and furosine (20%) and an increase in hardness, especially in einkorn cookies. PRACTICAL APPLICATIONS: To satisfy the ever‐increasing interest of the consumers in foods with better nutritional characteristics, the food industry is continuously exploring new formulations. Einkorn is a very promising candidate because of the outstanding composition of its flour. However, little information is available on sweet‐baked goods from einkorn. Our results clearly demonstrate that this wheat is perfect, from both the technological and the composition aspects, for preparing high nutritional value cookies with better nutraceutical properties than standard bread wheat cookies. Therefore, the food industry can directly use einkorn as an input ingredient for sweet‐baked goods using current production methods.
Validitas Skala Nyeri Non Verbal Pain Scale RevisedSebagai Penilai Nyeri di Ruang Perawatan Intensif Anak

Latar belakang. Berdasarkan berbagai penelitian, diperlukan skala nyeri yang divalidasi untuk menilai nyeri di ruang perawatan intensif anak dari aspek respon otonom dan evaluasi bentuk intervensi tata laksana nyeri yang diberikan. Tujuan. Mengetahui validitas alat pengukur skala nyeri non verbal pain scale (NVPS) yang dapat dipakai di ruang perawatan intensif anak. Metode. Subyek penelitian yang diberikan intervensi nyeri melalui berbagai prosedur pemeriksaan atau terapi, dinilai respon nyeri melalui perekaman video. Respon dinilai selama 2-10 menit sebelum, selama, dan setelah intervensi nyeri diberikan. Sebagai baku emas digunakan skala nyeri Wong Baker pain scale (WBPS) Hasil. Dari 38 sampel yang dinilai didapatkan sensitifitas NVPSR 85%, spesifisitas 66%, nilai prediksi positif 96%%, negatif prediksi negatif 50%. Nilai korelasi antara skala NVPSR dan WBPS adalah 0,95 (p<0,05). Kesimpulan. Non verbal pain scale revised(NVPSR) memiliki korelasi yang kuat dengan WBPS dalam menilai nyeri pada anak. Sensitifitas yang cukup tinggi sebagai alat skrening nyeri namun memiliki spesifitas yang sedang sebagai alat diagnostik nyeri pada anak.
Development and characterization of high temperature and -pressure alkaline electrolysis cells (HTP-AECs)

During the last three decades the Intergovernmental Panel on Climate Change (IPCC) has published several reports. Each new report has made it increasingly clear that climate change needs to be handled now sooner rather than later. There is strong evidence that climate change is caused predominantly by human activities, grounded in the unprecedented increase in greenhouse gas concentrations, including carbon dioxide, since the beginning of the industrial era. The fact that the worlds energy supply has been relying mainly on fossil fuels during the entire industrial era and until now elucidates the need to implement sustainable energy technologies that carry a significantly smaller carbon footprint compared to fossil fuel based technologies. A major challenge in the shift from a fossil based energy system to a sustainable energy system, based on renewable energy, is the storage of large amounts of electricity and the conversion of electricity to other useful forms of energy. We know that hydrogen can serve as an energy carrier between various forms of energy. Currently, electrolysis is the most mature approach to produce hydrogen from renewable sources which means the electricity has to come from renewable sources. Hydrogen can be stored as chemical energy for long periods of time and production is feasible on the kW-GW scale. In addition, the hydrogen can be used as a precursor to make synthetic fuels, e.g., for parts of the transport sector that is hard to electrify. As mentioned hydrogen can be produced using electrolysis which is the electrochemical splitting of water into its constituents, oxygen and hydrogen gas, using electricity as the driving force. Alkaline electrolysis is the most proven electrolysis technology and the most utilized technology on a commercial level. There is, however, room for improvement of the technology, in terms of improving the efficiency and increasing the hydrogen production rate per unit area of electrolysis cell. The work in this thesis is focused on improving the alkaline electrolysis technology utilizing a cell concept that allows for operation at high temperatures (150-250 C) and high pressure (20-40 bar), as this can significantly improve the cell efficiency and hydrogen production rate per unit area of cells. Ultimately this can lead to lower production prices of electrolyzed hydrogen. These electrolysis cells are termed high temperature and pressure alkaline electrolysis cells (HTP-AECs). The main objective in this project has been to develop, process and test porous oxygen electrodes. The starting point of the work carried out has been to identify electrocatalyst materials that are suitable to catalyse the evolution of oxygen; having in mind that the
Physicochemical surface characteristics in different pathogenic bacteria

Abstract Understanding physicochemical surface characteristics of microorganisms is vital in order to reduce or prevent bacterial adhesion as an important stage of pathogenicity. These characteristics are influenced by such factors as temperature, pH, or media determining the extent of bacterial adhesion. The present study adopted a simple technique, i.e. MATS (microbial adhesion to solvents) method, to better understand microbial cell surface characteristics in four different strains, namely Staphylococcus aureus, Listeria Monocytogenes, Escherichia coli, and Pseudomonas aeruginosa. For this aim, the effect of different concentrations of human blood serum in the media of these microorganisms on physicochemical characteristics of the microorganism was evaluated. The results revealed that the microorganisms possessed different characteristics at different doses of human blood serum. Some doses of human blood serum had no effect on hydrophobicity and electron donation and reception in the microorganisms whereas some doses could cause changes in these characteristics. These findings show that care should be taken when using different concentrations of antibiotics or other compounds such as rhamnolipids.
The Mechanical and In vitro Release Properties of Diazepam from Tablets Containing Fluid Bed Dried and Lyophilized Cocos nucifera Microcrystalline Cellulose

Aim: This study aimed to evaluate the mechanical and in vitro release properties of diazepam from tablets containing fluid bed dried and lyophilized microcrystalline cellulose (MCC) obtained from the matured fruit husks of Cocos nucifera (CN). Study Design: Method of experiment. Place and Duration of Study: Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka from March 2015 to September, 2016 Methods: Dried CN fruit husks were digested in sodium hydroxide to obtain alpha (α) cellulose which on hydrolysis with mineral acid (Hydrochloric acid) solution gave CN-MCC. The dry MCC obtained by either fluid bed or lyophilized drying of the wet CN-MCC were coded MCCF-Cocos and MCCL-Cocos respectively. Both MCCs were used in the formulation of diazepam tablets at 20, 30 and 40% w/w. Avicel PH 102 (AVC-102), was used as comparing standard. The tablets were evaluated for physical and dissolution properties using standard methods. Results: Results show the tablets passed the British Pharmacopoeia specifications for weight uniformity, crushing strength, disintegration time, friability and dissolution. Diazepam tablets containing MCCL-Cocos (coded DCL) were mechanically stronger than those containing MCCF-Cocos (coded DCF). Disintegration time was in the order of DCF > DCL tablets while friability was in the order of DCL < DCF tablets. Diazepam tablets containing AVC-102 (coded DAV) were mechanically stronger than DCL and DCF tablets. The dilution potential was in the order DAV > DCL > DCF. More than 80% of the diazepam content was released from DAV, DCL and DCF tablets. Conclusion: Generally, DAV, DCL and DCF tablets met the British Pharmacopoeia limits for mechanical properties and in vitro drug release with DCL tablets showing significantly (P = .05) superior mechanical properties while DCF showed faster drug release.
Molecular dynamics simulation of lactate dehydrogenase adsorption onto pristine and carboxylic-functionalized graphene

ABSTRACT Lactate dehydrogenase (LDH) is a tetrameric enzyme which is composed of two subunits known as LDHA and LDHB, which are encoded by the LDHA and LDHB genes respectively. LDH catalyses the last step in anaerobic glycolysis through the reversible conversion of pyruvate to lactate via coupled oxidation of NADH cofactor. The LDHA plays an important regulatory role in anaerobic glycolysis, by catalysing the final step of the process. Therefore, it is likely that increases in the expression level of LDHA in cancer cells could facilitate the efficiency of anaerobic glycolysis. Measuring the level of serum LDHA is a key step in the diagnosis of many cancer types. In this study, the adsorption, stability, and dynamics of LDHA on the surface of pristine graphene (PG) and carboxylated graphene (COOH-Graphene) were investigated using its molecular dynamics simulation. Variations in root mean square deviation, root mean square fluctuation, solvent accessible surface area and adsorption energy of the LDHA during the simulation were calculated to analyse the effect of PG and COOH-Graphene on the overall conformation of LDHA. Results showed that the adsorption of LDHA on COOH-Graphene is mostly mediated by electrostatic interactions, whereas on the PG, both Van der Waals and π-π interactions are prominent.
Modified relevance frequency feature weighting for email spam classification

Most of the research on the field of email spam classification focus on the feature selection and classification method. Research on the feature weighting method, however, is less explored despite the significant progress it has achieved. On this research, a Term Frequency-Relevance Frequency (TF-RF) feature weighting method is modified, referred as TF-MRF, in order to improve the performance of email spam classification. The purpose of the modification is to reduce the feature weighting errors on both high and low relevance features by increasing the capability in distinguishing high relevance features from low relevance ones, and therefore it will increase the accuracy of the classification. In order to observe its performance, TF-MRF is compared with four other feature weighting method, including TF-RF. Support Vector Machine (SVM) is chosen as classification method because of its high performance on text classification. Datasets from Ling Spam, Spam Assassin and CSDMC 2011 are used, which are divided .
Eye Shape Detection Based on Texture Modeling in Log-Polar Domain Using Principal Component Analysis and Recurrent Neural Network

This paper presents a method to detect the eye contour using recurrent neural network. Log-Polar transform is used to convert the changes of eye rotation and scales into translations. Principal component analysis is applied on the eye RGB color channels in order to obtain a stable texture representation regardless lighting conditions. A recurrent neural network is trained to discern the patterns of the texture values around the eye contour as well as to model the eye contour appearance with different eye states. The experimental results have verified that the recurrent network is able to detect the eye contour robustly. The proposed method outperforms the conventional methods in terms of accuracy and detection time.
Quantification of Sofosbuvir and Velpatasvir in Human Plasma using LCMS/MS Technique -Application to Pharmacokinetic Study

Objective: An effective high-performance liquid chromatography-tandem mass spectrophotometric (LCMS/MS) method was developed for the simultaneous quantitation of sofosbuvir (SOFOS) and velpatasvir (VELPA) in spiked human plasma. Methods: The extraction of both analytes from plasma was performed by Liquid-liquid extraction (LLE) technique. Separation was achieved on a Zorbax C18 stable bond (SB), C18 (4.6mm id x 50 mm) analytical column using acetonitrile: 1% formic acid (50:50) v/v with a flow rate of 600μl/min. The MS/MS analysis was performed in multiple reaction monitoring (MRM) to obtain the product ion m/z 530→242.3 for SOFOS, m/z 883.8 → 643.0 for VELPA and m/z 889.5 →732.6 for internal standard (ledipasvir). Results: The calibration curve was found linear over the range of 0.5→5000 ng/ml for SOFOS and 1.5→2000 ng/ml for VELPA. Intra and inerday accuracy (% nominal 98 → 102%), precision (% CV ≤3.8%) was excellent. Matrix effect (matrix factor 1.340 for SOFOS and 1.004 for VELPA), selectivity (% interference = 0) with a extraction recovery of 96.70% →98.30%. The stability (% nominal 95.85→98.90 %) of all types were within acceptable limit. Conclusion: The proposed method was applied successfully for the pharmacokinetic study of marketed dosage form in rabbit blood samples with single oral human equivalents dose. The developed method has further applied during clinical and preclinical trials in human and other experimental animals. Key words: Sofosbuvir, Velpatasvir, Bioanalytical, LC-MS/MS, Pharmacokinetic.
A Theoretic Study on Three Low-Density Parity-Check and BCH Concatenated Coding Schemes

Bose-Chaudhuri-Hocquenghem (BCH) codes have been widely used in flash memories for many years. Yet, in future “high-density” multi-level cell (MLC) flash memories, the raw bit-error-rate (BER) in NAND flash may increase up to around 10−2 at its life time, and hence the conventional hard-decision ECC, such as BCH codes, is no longer sufficient for these memories. Hence, the low-density parity-check (LDPC) codes, as a class of powerful ECCs, become an important candidate for future MLC memories. One of the most significant impediments to the use of LDPC codes in future MLC flash memories is the error floor phenomenon associated with the iterative decoding. So in this thesis, we wish to realize whether the concatenated coding scheme of LDPC codes and BCH codes can eliminate or improve the error floor phenomenon of the LDPC code or not. We thus analyze in this thesis three BCH and LDPC concatenated coding schemes: (1) a single BCH code concatenates with multiple LDPC codes; (2) multiple BCH codes concatenate with a single LDPC code; (3) multiple BCH codes concatenate with multiple LDPC codes. Our analysis shows that the concatenation of the two codes can effectively lower the error floor of the LDPC-only code system at the price of a small rate loss.
Operational floating current conveyor: characteristics, modelling and experimental results

A five-port general purpose analogue building block, termed as an operational floating current conveyor (OFCC), is described. The OFCC combines the features of a current feedback (CFB) operational amplifier, second generation current conveyor and operational floating conveyor (OFC). A simple implementation scheme of the OFCC is described and its terminal operational characteristics are used to yield a working model. The OFCC is then used as a single block to realize the current conveyors (CCII+ and CCII-). Experimental results are presented and show good behavioral agreement with simulation results.
Biomarkers of subclinical atherosclerosis in patients with psoriatic arthritis

Background: Psoriatic arthritis (PsA) is a chronic immune-mediated disease. It is associated with an increase in cardiovascular risk factors (obesity, hypertension, diabetes, and dyslipidemia), giving a higher risk of major adverse cardiovascular events. Patients with PsA have an increased incidence of subclinical atherosclerosis and endothelial dysfunction. The aim of this study is to perform a review of the biomarkers of subclinical atherosclerosis in patients with PsA. Methods: A search was performed in the electronic databases (PubMed, Web of Science, Scopus, and Embase) up until July 2017. Studies were considered if they included data on biomarkers of subclinical atherosclerosis in PsA, and each article was then reviewed for quality and clinical relevance. After completing the literature search, all screened literature was summarized and discussed in our study group (CaRRDs study group). Results: The initial search produced 532 abstracts, which were limited to 258 potentially relevant articles by preliminary review of the titles and by excluding review articles and case reports (n=274). A further 102 articles were deemed ineligible after examining the abstracts. Full texts of the remaining 156 articles were retrieved. Most articles were excluded because they were not relevant to the biomarkers of subclinical atherosclerosis in psoriasis and/or PsA. In the end, 54 articles were deemed eligible for this review. Conclusion: Patients with PsA showed more severe atherosclerotic disease compared with patients with only psoriasis. This may have been due to the higher systemic inflammatory burden from the combination of both diseases. In patients with PsA some molecules may be considered as markers of atherosclerotic disease, and their detection may be a prognostic marker, in addition to imaging procedures, for the development of atherosclerotic disease, and could be suitable for the management of patients with PsA.
Prevalence of gestational diabetes mellitus and associated risk factors amongst antenatal women attending urban health centre of Rajkot City, Gujarat

Background: Prevalence of gestational diabetes mellitus (GDM) vary widely depending on the region of the country, dietary habits, and socio-economic status. This study was undertaken to determine the prevalence of GDM and risk factors associated with it, in women attending an antenatal care (ANC) clinic at urban health training center in Rajkot city, Gujarat.Methods: This study enrolled women, with estimated gestational age between 24 and 28 week, attending UHC in Rajkot. After informing, women who consented to participate were given a standardized 75 g oral glucose tolerance test (OGTT). A proforma containing general information on demographic characteristics, socio-economic status, education level, parity, family history of diabetes and/or hypertension was filled up. Diabetes in pregnancy study group India (DIPSI) criteria for 75 g 2-h OGTT was used for diagnosing GDM.Results: Total of 366 women participated in the study and GDM was diagnosed in 36 (9.8%) women. Age, parity, BMI, family history of DM and hypertension were accessed and found to be not significant. History of hypertension in previous pregnancy was statistically significant with occurrence of GDM in present pregnancy.Conclusions: The prevalence of GDM was found to be 9.8 per cent in a UHC, Rajkot. Appropriate interventions are required for control of GDM and modifications of risk factors.
Desarrollo de una herramienta en Matlab para Sintonización de Controladores PID, utilizando algoritmos genéticos basado en técnicas de optimización multiobjetivo Development of a tool for tuning in matlab PID controllers, using genetic algorithms based on optimization techniques multiobjective

This document shows the versatility and efficiency by the development of a tool in Matlab for tuning proportional, Desarrollo de una herramienta en Matlab para sintonización de controladores PID, utilizando algoritmos genéticos basado en técnicas de optimización multiobjetivo, B. Acevedo, J. Fonseca, J. Gómez 82 integral and derivative controller (PID) using genetic algorithms (GA), based techniques for multiobjective optimization (MOP) based on Pareto fronts, calculating optimally constant proportional gain, integral gain and derivative gain (KP, KI, KD) for error minimization, mitigation of the maximum overshoot and settling time reduction in a given plant. Performance that is implementing genetic algorithms provide solutions to multiple targets in PID controllers, the tuning of existing PID controllers Sisotool Matlab compares different control systems closed loop formed by a transfer function is simulated, the controller and feedback loop. In these systems the behavior that drivers have to pass on a stair at the entrance to the ground is analyzed. With the realization of this tool is to optimize the shape of tuning PID controllers currently in use, today there is no tool to help structurally the tuning process without using a complex programming level and extensive knowledge in control, the use and integration of a number of techniques that allow a more versatile and efficient tool, usable in the task of tuning PID controllers which can simulate and calibrate by methods of evolutionary computational intelligence without have profound knowledge of programming.