Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental Studies on Critical Heat Flux in a Uniformly Heated Vertical Tube at Low Pressure and Flowrates

Investigations into critical heat flux at low flow and pressure conditions are of particular interest when predicting the nuclear reactor core behavior during Loss of Coolant accident (LOCA). Therefore, critical heat flux (CHF) has been investigated in a uniformly heated vertical round tube at two low system pressures and six low water flowrates. The results have been compared with two correlations which have different approaches and CHF look-up table. Good agreements have been obtained for the three comparisons at the lower sets of mass fluxes. The Bowring correlation was found to be the best to correlate the experimental results with Root Mean Square Error RMSE of 0.54% and 0.56% for the 5 bar and 15 bar system pressure respectively. A comparisons with the Shim and Lee correlation yielded RMSE of 0.23% and 5.74% for the two system pressure respectively. When the look-up table of Groeneveld et al. was used, RMES of 0.55% and 25.2% was obtained for the two system pressure respectively.
The Role of the Fins in the Equilibrium of the Swimming Fish: I. Wind-Tunnel Tests on a Model of Mustelus canis (Mitchill)

1. An attempt was made to determine the relationship of the fins to the equilibrium of the swimming dogfish. 2. Two factors at least are involved in this equilibrium; passive mechanical forces and reflex motions of the fins themselves. The part played by the automatic (passive) components was estimated by experimenting on a model of Mustelus canis mounted in a wind tunnel tested at a suitable air speed. 3. The equilibrium in the horizontal plane (yawing equilibrium--for turning movements) is unstable without fins, completely stable only in the absence of the first dorsal fin, and is neutral when all fins are present. 4. In the vertical plane (pitching equilibrium--for rising and diving turns) the equilibrium is unstable without fins, and this instability is greatly increased by the presence of the pectorals. The pelvics have little or no effect. 5. Stability and controllability are inversely related. The fish is comparatively stable in the horizontal plane, extremely controllable in the vertical plane. This fact is closely related to the flexibility of the body for lateral movements. 6. The results obtained in the wind tunnel were confirmed by amputation of the fins of the living dogfish. 7. The normal equilibrium of the swimming dogfish in the vertical plane is determined largely by the pectoral fins and the heterocercal tail. 8. The relationship of these facts to the problem of the evolution of the swimming chordates is considered.
Staphylococcal methicillin resistance: fine focus on folds and functions

Globalisation has entailed a massive increase in trade and human mobility facilitating the rapid spread of infectious agents, including those that are drug resistant. A particularly serious threat to human health is posed by methicillin-resistant staphylococcal strains which have acquired molecular mechanisms to evade the action of b-lactam antibiotics (BLAs). Full expression of high-level methicillin resistance involves a complex network of molecules and depends primarily on sufficient expression of a penicillin-binding protein with low sensitivity towards BLAs. Other factors include the fine-tuned regulation of autolytic activity of cell-wall components, as well as an optimal rate of peptidoglycan precursor formation and a highly specific peptidoglycan precursor structure. Three-dimensional structural data are available on several of the pieces involved in the jigsaw puzzle and provide a molecular basis for the understanding of methicillin resistance and for the design of new therapeutic strategies. 2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
Kinetics of protective antibodies are determined by the viral surface antigen

Delayed and weak virus neutralizing antibody (nAb) responses represent a hallmark correlating not only with the establishment of persistent infection but also with unsuccessful vaccine development. Using a reverse genetic approach, we evaluated possible underlying mechanisms in 2 widely studied viral infection models. Swapping the glycoproteins (GPs) of lymphocytic choriomeningitis virus (LCMV, naturally persisting, noncytolytic, inefficient nAb inducer) and vesicular stomatitis virus (VSV, nonpersisting, cytolytic, potent nAb inducer) transferred the only target of nAb’s from either virus to the other. We analyzed the nAb response to each of the 2 recombinant and parent viruses in infected mice and found that nAb kinetics were solely determined by the viral surface GP and not by the virus backbone. Moreover, the slowly and poorly nAb-triggering LCMV virion was a potent immunogenic matrix for the more antigenic VSV-GP. These findings indicate that the viral GP determines nAb kinetics largely independently of the specific viral infection context. They further suggest that structural features of viral GPs or coevolutionary adaptation of the virus’s GP to the host’s naive B cell repertoire, or both, may critically limit nAb kinetics and improvement of vaccine efficacy.
Monoliidi migreerimine mikroteenuste arhitektuurile: TransferWise'i näide. Migrating the Monolith to a Microservices Architecture: the Case of TransferWise

The aim of this thesis is to analyze the migration process from a monolithic application to a microservices based architecture. It is a case study of TransferWise. The main problem that is tackled in this paper is how to sustainably scale a tech startup company without compromising productivity. The main result of this paper is a successfully implemented proof-of-concept microservice and a generalized methodology for extracting microservices from a monolithic application. The thesis is in English and contains 46 pages of text, 5 chapters, 17 figures and 7 tables. Glossary of Terms and Abbreviations ABA American Bankers Association Android Mobile operating system based on Linux AngularJS Web application framework AOP Aspect-Oriented Programming API Application Programming Interface BDD Behavior Driven Development BIC Business Identifier Code CD Continuous Delivery Classpath Parameter that defines the location of classes CPU Central Processing Unit DI Dependency Injection Docker Deployment automation tool using software containers DTO Data Transfer Object Elasticsearch Search server based on Lucene Gradle Build automation tool Grails Web framework for the Java/Groovy platform Groovy Object-oriented programming language for the Java platform GUI Graphical User Interface H2 In-memory relational database management system written in Java Hamcrest Library of matcher objects Hibernate ORM Framework HTTP Hypertext Transfer Protocol IBAN International Bank Account Number IDE Integrated Development Environment IoC Inversion of Control iOS Mobile operating system by Apple Inc. ISO International Organization for Standardization Jackson JSON processor for Java
Sulfur Single-wavelength Anomalous Diffraction Crystal Structure of a Pheromone-Binding Protein from the Honeybee Apis mellifera L

Abstract Pheromone binding proteins (PBPs) are small helical proteins (∼13-17 kDa) present in several sensory organs from moth and other insect species. They are involved in the transport of pheromones from the sensillar lymph to the olfactory receptors. We report here the crystal structure of a PBP (Amel-ASP1) originating from the honey-bee (Apis mellifera) antennae and expressed as recombinant protein in the yeast Pichia pastoris. Crystals of Amel-ASP1 were obtained at pH 5.5 using the nano-drops technique of crystallization with a novel optimization procedure, and the structure was solved initially with the single-wavelength anomalous diffraction technique using sulfur anomalous dispersion. The structure of Amel-ASP1 has been refined at 1.6-A resolution. Its fold is roughly similar to that of other PBP/odorant binding proteins, presenting six helices and three disulfide bridges. Contrary to the PBPs from Bombyx mori (Sandler, B. H., Nikonova, L., Leal, W. S., and Clardy, J. (2000) Chem. Biol. 7, 143-151) and Leucophea maderae (Lartigue, A., Gruez, A., Spinelli, S., Riviere, S., Brossut, R., Tegoni, M., and Cambillau, C. (2003) J. Biol. Chem. 278, 30213-30218), the extended C terminus folds into the protein and forms a wall of the internal hydrophobic cavity. Its backbone groups establish two hydrogen bonds with a serendipitous ligand, n-butyl-benzene-sulfonamide, an additive used in plastics. This mode of binding might, however, mimic that used by one of the pheromonal blend components and illustrates the binding versatility of PBPs.
Group-Based Line Switching for Enhancing Contingency-Constrained Static Voltage Stability

A look-ahead contingency-constrained line switching problem is presented to enhance the static voltage stability of a look-ahead (say 30 minutes) base case, respecting a set of credible contingencies. This problem seeks to identify the ‘best’ network topology by switching out transmission lines to maximize the load margin of a look-ahead base case while ensuring the load margins of a set of credible contingencies are acceptable. Moreover, the voltage and thermal limitations are respected in the post-switching look-ahead base case. To solve the problem in an online environment, a group-based method is developed to reduce the complexity of the contingency constraints and enable tractable computation. Extensive numerical results on the IEEE 118-bus and the 1648-bus power systems examine the effectiveness of the proposed methodology.
Molecular mechanisms regulating myogenic determination and differentiation.

Abstract The myogenic regulatory factors are necessary for the determination and terminal differentiation of skeletal muscle. Gene targeting experiments have demonstrated that MyoD and Myf5 are important for myogenic determination whereas myogenin and MRF4 are important for terminal differentiation and lineage maintenance. During development, all trunk skeletal muscle is derived from the somite. Two spatially distinct sources of myogenic progenitors are defined by the expression of MyoD or Myf5 and these give rise to hypaxial and epaxial musculature. Both in vivo and in vitro analyses have provided a detailed picture regarding the molecular events controlling lineage determination, cell migration, terminal differentiation and tissue repair. Signal transduction pathways regulating cell cycle, protein-protein interactions and myogenic factor gene activation are implicated in the regulation of myogenesis. Recent experiments examining the origin and stem-cell capacity of satellite cells suggest that these cells may originate from the vascular system, are multipotential and may be useful for the treatment of several degenerative diseases.
The Effect of Electronic Design Automation (EDA) Towards Experimental Learning Method

Experimental learning method offers more experience and knowledge for learners. Electronic Design Automation (EDA), which refers to electronic computer-aided design (ECAD), is a category of software tools for designing electronic systems such as integrated circuits. Using EDA on experimental learning with different learning motivation could result on different learning achievement. This work was related in order to investigate learning achievement on experimental learning through the use of EDA. This research used quantitative approach in quasi-experimental frame. In this research, the compared conditions were the experimental learning method with EDA and the real component and motivation, which were grouped into two, high and low motivation. The research instrument used were questionnaires and tests, while the data analysis used two ways of ANAVA. The statistical analysis showed that there was difference learning achievement in Digital Technique Subject among experimental learning with EDA and the real component. Furthermore, there was interaction among the experimental learning with EDA and the learning motivation in terms of their effect towards learning achievement. Keywords—EDA; learning motivation; learning achievement; experimental learning method
A High Order Numerical Scheme for Incompress ible Navier-Stokes Equations

To solve the incompressible Navier-Stokes equations in a generalized coordinate system, a high order solver is presented. An exact projection method/fractional-step scheme is used in this study. Convective terms of the Navier-Stokes (N-S) equations are solved using fifth-order WENO spatial operators, and for the diffusion terms, a sixth-order compact central difference scheme is employed. The third-order Runge-Kutta (R-K) explicit time-integrating scheme with total variation diminishing (TVD) is adopted for the unsteady flow computations. The advantage of using a WENO scheme is that it can resolve applications using less number of grid points. Benchmark cases such as, driven cavity flow, Taylor-Green (TG) vortex, double shear layer, backward-facing step, and skewed cavity are used to investigate the accuracy of the scheme for two dimensional flow.
Analisis Kinerja MIMO Masif dengan Teknik Precoding Maximum Ratio Transmission

Channel State Information (CSI) at the base stations obtained via the uplink training is an important factor in cellular and multiuser Multi-Input Multi-Output (MIMO) communication networks. In massive MIMO cellular networks with pilotbased training, the most adopted approach is to employ the same set of orthogonal training symbols in each cell. This is called the full-pilot reuse (FPR) scheme. In this paper, we consider the lesscommon but a more practical approach where each cell uses different sets of orthogonal training symbols and call this scheme as the Different Orthogonal Pilot (DOP) sequences. In particular, we focus on the downlink performance of massive MIMO networks with the Maximum Ratio Transmission (MRT) precoder at the base stations. The analysis is performed in the large system regime where the number of antennas at each base station and the number of users at each cell tend to infinity with a fixed ratio. We obtain a new expression for the Signal to Interference plus Noise Ratio (SINR) in that regime, called the limiting SINR. Numerical simulations show that it can approximate the finite-size systems accurately. Furthermore, the simulations also indicate that the DOP scheme can give a better SINR and a higher user capacity compared to those of the FPR scheme.
The Research on the Forage Supplying Module on the Grassland during the Delaying and Resting Grazing Periods

To counter the problems of Naiman Banner during the delaying and resting grazing period,such as the insufficient utilizable forage quantity,low forage quality and low utilization rate,some more efficient techniques,such as enclosure of the grassland,supplementary sowing,the establishment of the high quality artificial grassland by mixed sowing and the establishment of the high productive land for forage yield,were extended.The utilization rate of the forage was increased by some methods,such as silage and micro-silage.In addition,comprehensively considering the local altering rules of the animal flocks which is fed in houses,the traits of the forage demanding and the characteristics of supplying times of all kinds of forage resources,the module that is adapted for the balance supplying of forage under the conditions of yearly forbidding browse and seasonally forbidding browse was advanced.
Performance Evaluation of Bluetooth Low Energy Communication

Bluetooth Low Energy (BLE), also known as Bluetooth Smart is the new power efficient version of Bluetooth. With the massive increase in the use of IoT devices, their compatibility and suitability for use with BLE, it has become an important protocol for communication. The performance of the protocol in terms of throughput, however, remains untested. Several parameters like connection interval, packet size per connection interval, data length extension and others constitute the implementation of the BLE protocol on a device. These parameters directly or indirectly effect the throughput of devices communicating over BLE. In this paper, we evaluated BLE performance by performing experiments to calculate throughput with varying values of connection interval and MTU size of application payload. We provide experimental values of throughput and compare it with the theoretically expected results and discuss the pattern and aberration found.
Prototypes of User Interfaces for Mobile Applications for Patients with Diabetes

We live in a heavily technologized global society. It is therefore not surprising that efforts are being made to integrate current information technology into the treatment of diabetes mellitus. This paper is dedicated to improving the treatment of this disease through the use of well-designed mobile applications. Our analysis of relevant literature sources and existing solutions has revealed that the current state of mobile applications for diabetics is unsatisfactory. These limitations relate both to the content and the Graphical User Interface (GUI) of existing applications. Following the analysis of relevant studies, there are four key elements that a diabetes mobile application should contain. These elements are: (1) blood glucose levels monitoring; (2) effective treatment; (3) proper eating habits; and (4) physical activity. As the next step in this study, three prototypes of new mobile applications were designed. Each of the prototypes represents one group of applications according to a set of given rules. The most optimal solution based on the users’ preferences was determined by using a questionnaire survey conducted with a sample of 30 respondents participating in a questionnaire after providing their informed consent. The age of participants was from 15 until 30 years old, where gender was split to 13 males and 17 females. As a result of this study, the specifications of the proposed application were identified, which aims to respond to the findings discovered in the analytical part of the study, and to eliminate the limitations of the current solutions. All of the respondents expressed preference for an application that includes not only the key functions, but a number of additional functions, namely synchronization with one of the external devices for measuring blood glucose levels, while five-sixths of them found suggested additional functions as being sufficient.
Optimal Disintegration Strategy in Multiplex Networks under Layer Node-Based Attack

From social networks to complex infrastructures, many systems could be described by multiplex networks formed by a set of nodes connected via more than one type of links. Network disintegration, which is the problem of identifying a set of nodes or edges whose removal would maximize the network collapse, is significant for dismantling harmful networks. In this article, we consider the optimal disintegration strategy problem in multiplex networks and extend the attack mode to the layer node-based attack. An optimization model is proposed to search the optimal strategy of a multiplex network under layer node-based attack with fix attack length. Two types of strategies based on the information of multiplex nodes and layer nodes, respectively, are also given for comparison. Through experiments in both model networks and real networks, we found that the approximate optimal strategies could be identified by solving the model. The properties of the optimal strategies are also summarized.
Confessions of A MOOCER: An Autoethnographic Inquiry on Online Distance Education

Massive Open Online Courses (MOOCs) are dramatically restructuring, reshaping, and redefining the vast landscape of teaching and learning across the globe. With MOOCs’ ubiquity, openness, and accessibility, they have become a new platform for teacher professional development. Utilizing a co-constructed narrative inquiry, this paper aimed to examine aspects of our memories, perspectives, and experiences in successfully completing Teach English Now! a 150-hour online Teaching English to Speakers of Other Languages (TESOL) Certificate Course from Arizona State University, United States of America via Coursera (www.coursera.org) as the MOOC platform. Acting as reflective practitioners and as teachers-as-researchers, we unpacked how we traversed the massive information superhighway in our quest for teacher professional development, what it was like to be an online learner, how we saw our role, why we believe what we believe about MOOCs’ potential, and how we think all of these affect our decisions and practices in our classrooms and contexts. Data from our individual journals, individual reflections, and peer discussion revealed how MOOCs’ features such as ‘openness’ and ‘flexibility’ as afforded by ubiquitous technology, sound course design, and strong learning community support have influenced us personally, socially, and professionally, making it a practical platform for teacher professional advancement particularly in developing countries such as the Philippines. Andragogical and pedagogical implications are provided in the light of our MOOC experience.
Experimental Investigation on Oil Spray Cooling With Hairpin Windings

Hairpin windings are gaining increasing popularity in recent years due to their advantages in improving electrical machine performance while reducing manufacturing time and costs. Their geometrical features introduce new challenges and opportunities on thermal management. In particular, spray cooling is increasingly being used, since hairpin windings open up regular and accurately defined gaps in the end-windings compared to the traditional random windings. To date, technical literature on the effectiveness of spray cooling with hairpin windings is lacking, with no practical guidelines available to researchers. In this article, taking an existing hairpin-wound stator, a test rig is developed to investigate the cooling ability of different spray cooling setups on the end-windings. Three types of commercial spray nozzles are chosen to carry out a series of experiments, varying the oil flow rate, pressure, outlet velocity, and number of nozzles. The winding temperature and heat transfer coefficients are presented and discussed. Furthermore, the efficiency of spray cooling is reviewed based on the experimental results. Finally, suggestions on designing similar cooling setups and increasing the cooling efficiency are also provided.
Mobile Cloud Computing Architecture Model for Multi-Tasks Offloading

In modern era the cell phones has born through the significant technological advancements. But this resides a low multi tasks entity. Many people use mobile devices instead of PC’s. Cell phones has limited number of resources like limited storage, battery time and processing. The cloud computing offloading deals with these limitations. Cloud computing become more attractive as it reduce the cost and also time efficient. Business of all sizes can’t afford to purchase hardware and softwares but cloud computing provide these resources and executes multiple tasks and allows the user to access their data and provide other control in each level of cloud computing. All of these techniques save smart phones properties or capabilities but it also becomes the reasons of communication cost between cloud and smart phone devices. The main advantage of cloud computing is to provide multiple properties at different prices. These applications has goal to attain versatile performance objective. In this research work, an architecture model for multi tasks offloading designed to overcome this problem. For this purpose CloudSim simulator use with the NetBeans and implement the MCOP algorithm. This algorithm solves the execution timing issue and enhances the mobile system performance. In this tasks are partitioning into two parts and then implemented on cloud site or locally. It reduces the time response and communication cost or tasks execution cost. Keywords: Mobile Cloud Computing, Mobile Computing Offloading, Smart Mobile Devices, Optimal Partitioning Algorithm.