Miracle-dz/UniFAR-FTUs huggingface dataset:
Citizens’ perception of modern pig production in Germany: a mixed-method research approach

Purpose – The wide divergence of the people’s expectations and agricultural reality results in conflicts between the agricultural sector and the general public. Contemporary animal husbandry systems are being increasingly critically addressed by media; however, there is no information about peoples’ perceptions and attitudes concentrating precisely on specific animal husbandry systems. The purpose of this paper is to explore citizens’ perceptions, expectations and main points of criticism in regard to intensive pig production in Germany, and to identify and describe distinct population groups reflecting different attitudes. Design/methodology/approach – A mixed method approach combining qualitative focus groups with a quantitative online survey has been employed. Focus groups capture a wide variety of opinions and concerns in an exploratory manner. Based on these findings, the quantitative survey (n=1,500 citizens) allowed the identification and characterisation of population groups with identical attitud.
The ALIVE system: full-body interaction with autonomous agents

The cumbersome nature of wired interfaces and the limited nature of the interaction with graphical objects has so far limited the range of application of virtual environments. We discuss the design and implementation of a novel system, called ALIVE, which allows wireless full-body interaction between a human participant and a rich graphical world inhabited by autonomous agents. Based on results obtained with real users, the paper argues that this kind of system can provide more complex and very different experiences than traditional virtual reality systems. The ALIVE system significantly broadens the range of potential applications of virtual reality systems; in particular the paper discusses novel applications in the area of training and teaching, entertainment and last but not least, digital assistants or interface agents. <<ETX>>
Clinical Depression Analysis Using Speech Features

Depression is a most common severe mental disturbance health disorder causing high societal costs. In clinical practice rating for depression depends almost on self questionnaires and clinical patient history report opinion. In recent years, the awareness has generated for automatic detection of depression from the speech signal. Some queries are raised that which features are more responsible for depression from speech and which classifiers gives good results. By identifying proper features from speech signal system even one can save the life of a patient. In this paper, a survey of speech signal features which relates for depression analysis is presented. Specially focused on adolescence speech. After surveying it is hypothesized that many speech features are there which are responsible for depression like linear features Prosodic, cepstral, spectral and glottal features and non-linear feature Teager energy operator (TEO). Some classification methods for depression analysis from previous studies are summarized.
Immunotherapy of tuberculosis with Mycobacterium leprae Hsp65 as a DNA vaccine triggers cross-reactive antibodies against mammalian Hsp60 but not pathological autoimmunity

Despite substantial efforts in recent years toward the development of new vaccines and drugs against tuberculosis (TB), success has remained elusive. Immunotherapy of TB with mycobacterial Hsp65 as a DNA vaccine (DNA-hsp65) results in a reduction of systemic bacterial loads and lung tissue damage, but the high homology of Hsp65 with the mammalian protein raises concern that pathological autoimmune responses may also be triggered. We searched for autoimmune responses elicited by DNA-hsp65 immunotherapy in mice chronically infected with TB by evaluating the humoral immune response and comprehensive histopathology using stereology. Cross-reactive antibodies between mycobacterial and mammalian Hsp60/65 were detected; however, no signs of pathological autoimmunity were found up to 60 days after the end of the therapy.
Resveratrol-induced apoptotic death in human U251 glioma cells

Resveratrol (trans-3,4′,5-trihydroxystilbene) is a naturally occurring polyphenolic compound highly enriched in grapes, peanuts, red wine, and a variety of food sources. Resveratrol has antiinflammatory and antioxidant properties, and also has potent anticancer properties. Human glioma U251 cells were used to understand the molecular mechanisms by which resveratrol acts as an anticancer agent, since glioma is a particularly difficult cancer to treat and eradicate. Our data show that resveratrol induces dose- and time-dependent death of U251 cells, as measured by lactate dehydrogenase release and internucleosomal DNA fragmentation assays. Resveratrol induces activation of caspase-3 and increases the cleavage of the downstream caspase substrate, poly(ADP-ribose) polymerase. Resveratrol-induced DNA fragmentation can be completely blocked by either a general caspase inhibitor (Z-VAD-FMK) or a selective caspase-3 inhibitor (Z-DEVD-FMK), but not by a selective caspase-1 inhibitor. Resveratrol induces cytochrome c release from mitochondria to the cytoplasm and activation of caspase-9. Resveratrol also increases expression of proapoptotic Bax and its translocation to the mitochondria. Resveratrol inhibits U251 proliferation, as measured by MTS assay [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt], and induces G0/G1 growth arrest, as determined by flow cytometry. The cyclin-dependent kinase inhibitor, olomoucine, prevents cell cycle progression and resveratrol-induced apoptosis. These results suggest that multiple signaling pathways may underlie the apoptotic death of U251 glioma induced by resveratrol, which warrants further exploration as an anticancer agent in human glioma.
Un algoritmo multi-objetivo NSGA-II para la programación de los pasos de laminación en caliente de aceros

The problem of Scheduling Hot Rolling Pass of Steels is very complex because it has large spaces search for solutions. The aim of this work was the Multi-Objective Optimization (MOO) of hot rolling steel sheets in a finishing train of six steps, implementing the second generation of Nondominated Sorting Genetic Algorithm (NSGA-II). It was used two different crossover (AG1 y AG2) operators and two objective functions. These were the total time of rolling and bending of the work rolls. Two kinds of computational experiments were performed: a) Search for the best solution, b) benchmarking of both NSGA-II configurations. For each experiment was obtained 3000 solutions. Rolling time, separation roll force, and exit thickness for each rolling stand are calculated. A flow stress constitutive model for roll force was used, valid for any low, medium carbon and Nb, Ti, V microalloyed steels. The solutions are reported, choosing some of them between 100 based on the lower computing time. The 100 solutions were generated in times lower than 70 s. AG1 had lower computing times AG2. The NSGA-II implementation minimized both the rolling time as crown of the work rolls, at low computational costs and ensuring that the flatness of strip will always be lower than international standards.
A peak detect and hold circuit using ramp sampling approach

The paper presents a peak detect and hold circuit for nuclear radiation pulse amplitude measurement. The design is to use two ramps with different slopes to sample the input voltage to avoid overshoot during sampling stage. The holding capacitor connected to input instead of charging source to avoid pedestal voltage error. Simulation result indicates that measuring voltage error is less than 0.1% or 1 mV with the voltage droop less than 20 uV/us for 1V Gaussian pulses with peaking time from 1 to 12 us.
BUILDING OF AN EFFECTIVE MAXIMIZATION APPROACH FOR ENSURING QUALITY OF SERVICE IN CLOUD

Like a valuable means to offer computing services to clients when needed, cloud setting is becoming more appealing. In the view reason for providers of cloud, profit is easily the most major problem that is mostly determined by way of cloud platform arrangement in specified market demand. Ideas study concerning the multi-server configuration and services information contributor so that its profit is used. A dual leasing product is forecasted for providers which combine lengthy-term leasing by way of short-term leasing, which assures quality-of-service needs in modifying system workload, but furthermore decrease resource waste. The forecasted resource leasing product is considered first of all where short-term leasing in addition to lengthy-term leasing are incorporated striving at existing issues. By way of our suggested resource leasing design, temporary servers are leased for the whole demands whose duration of waiting are equal to limit, that may assurance the entire demands are offered by high service quality hence our bodies is advanced to established resource leasing plan regarding service excellence.
What Fosters Favorable Attitudes Toward Using Travel Mobile Applications?

Abstract This study examined the effect of image and personal innovativeness on perceived enjoyment and perceived usefulness in shaping attitudes toward using travel mobile applications, and assessed the effect of users’ years of experience with general mobile applications on the proposed research model. The target population is travelers in the United States who had experience in using travel mobile applications and whose e-mail addresses can be accessed from the purchased database available at a university located in the south central United States. Data were collected through an online survey using a self-administered questionnaire. A total of 202 responses were used for data analysis. The results of the findings suggest that image and personal innovativeness positively influence perceived enjoyment as well as perceived usefulness. Theoretical and practical implications are further discussed.
Personality, parental rearing behaviour and parental loss in attempted suicide: a comparative study

Thirty psychiatric patients (aged 18‐29) who had attempted suicide were compared with 2 matched control groups, one consisting of nonsuicidal psychiatric patients and the other of normal subjects, for personality patterns, parental rearing practices and personal loss before the age of 15. The instruments used were the Eysenck Personality Questionnaire (EPQ), the Lazare‐Klerman‐Armor Trait Scale (LKAS), the Narcissistic Personality Inventory (NPI) and the Own Memories of Child‐Rearing Experiences (EMBU). Patients admitted for suicide attempts differed significantly from normals on several personality dimensions, whereas suicide attempters did not have personality characteristics that made them substantially different from nonsuicidal psychiatric controls. The suicide attempters had experienced significantly more negative and less positive parental rearing factors than normals, but no difference was found between suicidal and nonsuicidal patients for own memories of parental rearing patterns. Parental loss due to divorce had occurred significantly more often among suicide attempters than among both nonsuicidal psychiatric patients and normals.
C-GRAAL : C ommon-neighbors-based global GRA ph AL ignment of biological networks w z

Networks are an invaluable framework for modeling biological systems. Analyzing protein–protein interaction (PPI) networks can provide insight into underlying cellular processes. It is expected that comparison and alignment of biological networks will have a similar impact on our understanding of evolution, biological function, and disease as did sequence comparison and alignment. Here, we introduce a novel pairwise global alignment algorithm called Commonneighbors based GRAph ALigner (C-GRAAL) that uses heuristics for maximizing the number of aligned edges between two networks and is based solely on network topology. As such, it can be applied to any type of network, such as social, transportation, or electrical networks. We apply C-GRAAL to align PPI networks of eukaryotic and prokaryotic species, as well as inter-species PPI networks, and we demonstrate that the resulting alignments expose large connected and functionally topologically aligned regions. We use the resulting alignments to transfer biological knowledge across species, successfully validating many of the predictions. Moreover, we show that C-GRAAL can be used to align human–pathogen inter-species PPI networks and that it can identify patterns of pathogen interactions with host proteins solely from network topology.
The “New” Head and Neck Cancer Patient—Young, Nonsmoker, Nondrinker, and HPV Positive

Objective The near epidemic rise of the incidence of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinomas (OPSCC) presents the practitioner with a “new” head and neck cancer patient, vastly different from those with the traditional risk factors who formed the basis of most practitioners’ training experience. Accordingly, a thorough and disease-specific evaluation process is necessitated. This article will review the evaluation of the HPV-related cancer patient, including a review of the HPV-positive oropharyngeal cancer epidemic from the surgeon’s perspective, evaluation of the primary lesion, evaluation of the neck mass, and role of imaging, to provide a framework for addressing the challenging questions patients may ask. Data Sources Available peer-reviewed literature and practice guidelines. Review Methods Assessment of selected specific topics by authors solicited from the Head and Neck Surgery and Oncology Committee of the American Academy of Otolaryngology—Head and Neck Surgery Foundation and the American Head and Neck Society. Conclusions and Implications for Practice The dramatic rise in OPSSC related to HPV is characterized by a “new” cancer patient who is younger and lacks traditional risk factors. Today’s caregiver must be prepared to appropriately evaluate, counsel, and treat these patients with HPV-positive disease with the expectation that traditional treatment algorithms will evolve to maintain or improve current excellent cure rates while lessening treatment related side effects.
Emergence of the Plasmid-Mediated mcr-1 Gene in Clinical KPC-2-Producing Klebsiella pneumoniae Sequence Type 392 in Brazil

Caio Augusto Martins Aires,a Orlando Carlos da Conceição-Neto,a Thamirys Rachel Tavares e Oliveira,a Carolina Frizzera Dias,b Lara Feital Montezzi,c Renata Cristina Picão,c Rodolpho Mattos Albano,d Marise Dutra Asensi,a Ana Paula D’Alincourt Carvalho-Assefa Laboratório de Pesquisa em Infecção Hospitalar (LAPIH), Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Brazila; Comissão de Controle de Infecção Hospitalar, Hospital Santa Casa da Misericórdia de Vitória, Vitória, Brazilb; Laboratório de Investigação em Microbiologia Médica (LIMM), Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazilc; Departamento de Bioquímica, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazild
Reward for Taking Risk at DSE - An Application of Zero Beta CAPM

Expecting extra return for taking extra risk is commonplace in Finance. However due to different market peculiarities, which include various types of market imperfections as well, often times risk return structure in any particular market may not follow theoretical predictions. We tried to investigate this issue in the context of Dhaka Stock Exchange (DSE) using weekly data of 87 publicly listed shares from 2000 to 2008. Assuming absence of risk free rate and staying within mean variance outlook of portfolio evaluation we calculated return on synthetically composed zero beta portfolio and from that we tried to measure the reward for taking risk at DSE. We have found that statistical relationship between taking risk and return is negative and statistically significant for DSE.
Nano-Contact Transfer with Gold Nanoparticles on PEG Hydrogels and Using Wrinkled PDMS-Stamps

In the present work, a soft lithographic process is used to create nanometer-sized line patterns of gold nanoparticles (Au NPs) on PEG-based hydrogels. Hereby nanometer-sized wrinkles on polydimethylsiloxane (PDMS) are first fabricated, then functionalized with amino-silane and subsequently coated with Au NPs. The Au NPs are electrostatically bound to the surface of the wrinkled PDMS. In the next step, these relatively loosely bound Au NPs are transferred to PEG based hydrogels by simple contacting, which we denote “nano-contact transfer”. Nano-patterned Au NPs lines on PEG hydrogels are thus achieved, which are of interesting potential in nano-photonics, biosensor applications (using SERS) and to control nanoscopic cell adhesion events.
Serum Lipids, Lipoproteins and Macrovascular Disease in Non‐insulin‐dependent Diabetics: A Possible New Approach to Prevention

The relationship between macrovascular disease and serum lipids, low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL), and subfraction cholesterol, and apolipoproteins has been examined in 53 female and 95 male patients with non‐insulin‐dependent diabetes mellitus (NIDDM). In males, those with macrovascular disease had higher serum and LDL cholesterol concentrations than those without. In females, those with macrovascular disease had higher levels of serum triglyceride, cholesterol, LDL cholesterol, as well as lower HDL, HDL2, and HDL3 cholesterol and apoprotein A‐1, than those without. On multivariate analysis, LDL cholesterol was the most important association with macrovascular disease in males and apoprotein A‐1 in females.
An Algorithm-Hardware-System Approach to VLIW Multimedia Processors

Very Long Instruction Word (VLIW) processor architectures for multimedia applications are discussed from an algorithm, hardware and system based point of view. VLIW processors show high flexibility and processing power, as well as a good utilization of resources by compiler-generated code, but their exclusive exploitation of instruction level parallelism (ILP) decreases in efficiency as the degree of parallelism increases. This is mainly caused by characteristics of multimedia algorithms, increasing wiring delays, compiler restrictions, and a widening gap between on-chip processing speed and available bandwidth to external memory. As new multimedia applications and standards continue to evolve (MPEG-4), the demand for higher processing power will continue. Therefore, parallel processing in all its available forms will have to be exploited to achieve significant performance improvements. We show that, due to the diminishing returns from a further increase in ILP, multimedia applications will benefit more from an additional exploitation of parallelism at thread-level. We examine how simultaneous multithreading (SMT), a novel architectural approach combining VLIW techniques with parallel processing of threads, can efficiently be used to further increase performance of typical multimedia workloads.
Paternity and parental leave policies across the European Union

RAND Europe is a not-for-profit organisation whose mission is to help improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors. The European Platform for Investing in Children (EPIC) was set up to explore demographic and economic challenges in the EU from a child and family-focused perspective. Its purpose is to share the best of policymaking for children and their families, and to foster cooperation and mutual learning in the field. This is achieved through information provided on the EPIC website, which enables policymakers from the member states to search evidence-based child-focused practices from around the EU and to share knowledge about practices that are being developed, and also by bringing together government, civil society and European Union representatives for seminars and workshops to exchange ideas and learn from each other. RAND Europe is an independent not-for-profit policy research organisation that aims to improve policy and decisionmaking in the public interest, through research and analysis. RAND Europe's clients include European governments, institutions, non-governmental organisations and firms with a need for rigorous, independent, multidisciplinary analysis. The document is designed to provide insights into issues of interest to policymakers and practitioners. It has been reviewed externally by an EPIC expert in child and family policy, and internally, following RAND's quality assurance processes. The opinions expressed do not necessarily reflect the position of the European Commission.
The Role of the Sales-Service Interface and Ambidexterity in the Evolving Organization

Despite a long history of independent sales and service functions within organizations, customers are pressuring organizations to rethink their sales and service operations. Specifically, customers expect organizations to offer a “single face” of the firm rather than being forced to interact with multiple agents across both sales and service throughout their relationships. As firms attempt to meet these customer demands, they have countless options to integrate sales and service operations, but little is known about which strategies are most effective. This article attempts to shed new light into the challenges and potential benefits of sales-service integration, in an effort to spur research in this area and better inform this managerial challenge. Specifically, we formalize the concept of the sales-service interface, discuss how it relates to sales-service ambidexterity, and identify several opportunities for future research. Given the complexity of the sales-service interface, we contend that future researchers must view these issues through a multilevel lens and, as a result, we focus on identifying opportunities ideally suited for testing in a multilevel environment. The goal of this article is to provide a platform for researchers to tackle this challenging problem and generate new insights into how best to meet customer’s evolving demands.