Miracle-dz/UniFAR-FTUs huggingface dataset:
Association between Periodontitis and Interleukin-8 in Saliva 치주병과 타액내 Interleukin

Association between Periodontitis and Interleukin-8 in Saliva Hyuntae Kim Dentistry major School of Dentistry Seoul National University Objective: Periodontitis has been known as chronic inflammatory disease initiated by an unbalance between pathologic oral microbiota and the host defense. Several studies suggested that interleukin-8 (IL-8) is associated with periodontitis in gingival crevicular fluids (GCF) and serum, but the relationship between IL-8 and periodontitis in whole saliva has not been widely reported. This study aims to evaluate the association between periodontal severity and the whole salivary IL-8 level. Methods: Participants were recruited from the Yangpyeong health cohort study from 2010 to 2014 as the baseline for dental cohort. The final 623 participants were selected for the analysis. Periodontitis was assessed by a dentist using Centers for Disease Control and Prevention/American Academy of Periodontology (CDC/AAP) criteria through panoramic radiographs. IL-8 was assayed using multiplexed bead immunoassay (Luminex). Information about age, sex, smoking, drinking, and education were obtained by interview. Analysis of variance (ANOVA) analysis was applied to assess crude association between salivary IL-8 and periodontitis, and analysis of covariance (ANCOVA) controlled for various confounders. Results: Mean salivary level of IL-8 was not discriminated between periodontitis severity groups (ANOVA, p-value=0.235). After controlling for confounders, statistical difference of salivary IL-8 was not observed between groups (ANCOVA, pvalue=0.375). Neither age nor sex stratified analyses showed significant difference. Conclusion: There was no statistically significant difference of salivary IL-8 between periodontitis groups. Further study is indicated to confirm the result.
Output voltage control system for a three-level neutral-point clamped quasi-Z-source inverter

This paper presents three closed loop control systems for a three-level neutral-point-clamped quasi impedance source inverter. These control systems are designed and simulated to enable validation of their operation for improvement of the capabilities of the three-level neutral-point- clamped quasi impedance source inverter during variable input voltage situations. PID controller-based control systems could be used in photovoltaic applications in which the output voltage of the solar array depends on the irradiance and the temperature produces variable input voltage. Streszczenie. W artykule przedstawiono trzy algorytmy sterowania w petli zamknietej, bazujące na regulatorach PID, dla trojpoziomowego przeksztaltnika z diodami poziomującymi zasilanego ze źrodla quasi-Z. Przeprowadzono badania symulacyjne omawianych algorytmow, w celu potwierdzenia ich pozytywnego wplywu na prace przeksztaltnika w warunkach zmienności napiecia wejściowego. Proponowane strategie mają potencjalne zastosowanie w fotowoltaice, gdzie wystepują zmiany napiecia wyjściowego w zalezności od temperatury i naslonecznienia. (Sterowanie napieciem wyjściowym dla trojpoziomowego falownika z diodami poziomującymi zasilanego ze źrodla quasi-Z).
Revue générale Comprendre la variabilité de la pression artérielle et de la fréquence cardiaque To understand blood pressure and heart rate variability

Objectives. – To review current data on the heart rate and blood pressure variability. Data sources. – Search through MedlineTM databases of articles in french or english. Data selection. – Original articles and case reports were selected according to their quality and main advances. The articles were analysed in order to obtain current data about the methods of study and clinical application of blood pressure and heart rate variability. Data synthesis. – Various regulatory systems in the cardiovascular system play crucial roles in controlling and assuring adequate perfusion of the peripheral tissues.Among them the baroreceptor reflex is the most important regulatory mechanism in the short-term control of the heart rate and blood pressure, and operates through the autonomic nervous system. The gain of the cardiac baroreflex further referred to, as baroreflex sensitivity is an interesting way to study this system. Unfortunately, with our current knowledge, it is not possible to predict the instantaneous output of the baroreceptor in response to instantaneous changes in input within a frequency range of physiological importance. The fast Fourier transform can describe variables as the sum of elementary oscillatory components and it has been established as practical clinical methods for detecting abnormalities in cardiovascular control. A time–frequency distribution provides an indication of how the spectral energy distribution varies with time and it is an interesting tool in non-stationary data. One of the major motivations behind spectral * Auteur correspondant. Adresse e-mail : edmundo@rockefeller.univ-lyon1.fr (E.P. Souza Neto). Annales Françaises d’Anesthésie et de Réanimation 22 (2003) 425–452 www.elsevier. com/locate/annfar © 2003 Éditions scientifiques et médicales Elsevier SAS. Tous droits réservés. DOI: 10.1016/S0750-7658(03)00134-5 analysis is the hope that the combination of time–domain and frequency–domain analyses will provide dynamical informations about the relation between blood pressure and heart rate. © 2003 Éditions scientifiques et médicales Elsevier SAS. Tous droits réservés. Mots clés : Analyse spectrale ; Baroréflexe ; Pression artérielle ; Rythme cardiaque ; Système nerveux autonome
Craniofacial Anthropometry in Newborns and Infants

Objective: The face is involved in many syndromes of dysmorphogenesis. The soft tissue facial landmarks are known to be influenced by age, race and sex and it is imperative to identify a balance between them before reconstructive surgery. Further, with knowledge of standard facial traits, an individualized norm can be established to optimize facial attractiveness. Material & Methods: Measurements were made on 60 infants (30 males and 30 females) aged between 1-4 months and 60 newborns (30 males and 30 females) with a view to establish the criterion of facial anthropometry for this age group in North Indians. A special emphasis was given in this study to sexual dimorphism. Findings: The mean value and range for all the parameters was determined for the North Indian population. A statistically significant sexual dimorphism was noted to exist in ear length (P<0.01) and length of the philtrum (P<0.05). Philtral–commissural ratio was determined for North Indians, philtrum width=oral width/3.2. Conclusion: The local values derived from well defined populations should be used as reference in the evaluation of a case with dimorphic features. This study demonstrates the existence of a partial positive correlation between philtral width and oral width, i.e. when one increases the other also increases and vice versa. The Philtral–commissural relationship is expected to assist in planning philtral construction in cleft lip patients.
Reconsidering the Concept of Modern Professionals

While the number of occupations known as "professions" has increased, studies in economics have not secured a grasp of old and new professions within the same context. One reason is that they do not view certain occupations in terms of the concept of "profession" as an ideal type. This study reconsiders many aspects of professions and extracts the most notable features that char­ acterize an occupation as a profession. The most crucial characteristic of an ideal profession type is a codified body of knowledge. A profession needs to be socially accepted as being highly devel­ oped and not substitutable. In addition, the occupational function of a profession involves urgency and indispensability, and the profession must be at the vertex of its field while using a common body of knowledge. In categorizing modern professionals based on these criteria, we arrived at five types: established professions, new professions, semi-professions (A), semi-professions (B), and skilled workers and experts.
Gut Microbiota Role in Liver Regeneration:Evidences and Novel Insights

A large majority of human organism areas happens to be massively colonized by a diversified microbial community and the association of these bacterial pools makes up the so-called microbiota. This enormous population is mostly constituted by bacteria and fungi. These microorganisms are estimated to outnumber human cells Bianconi et al. [1], Hao & Lee [2] and Whitman et al. [3]. Human pathophysiological status highly depends on microbiota activity; its presence is in fact necessary for healthy development, as well as for backing up immune system in the defense from pathogens Grice et al. [4] and Keijser et al. [5]. Microbiota is held responsible for a large number of key physiological functions in human body; in fact, it was recently reported that it plays a pivotal role in tastes perceptions Frumento [6] by secreting acids that, degrading esters molecules in mouth, mouth bacteria exert an important influence on both oral and retropharyngeal sensing. Moreover, microbiota has been demonstrated to be involved in HCV (Hepatitis C virus) infection, favoring it both when bacterial composition balance is lost and phylotypes diversity is lowered Frumento [7]). Within this complex scenario, it is not surprising that the gut-liver axis could be
Quantifying Uncertainty in Grey-Box Buidling Models Arising from Smart Meter Energy Data Sampling Frequency

The increasing availability of high resolution smart meter data is an opportunity to develop datadriven models of residential buildings. However, model performance may be undermined by the very density of this data using models which take advantage of steady state approximations could reduce uncertainty in results. This requires a better understanding on the relation between model uncertainty and the time resolution of the input data used. We apply a grey-box model to smart meter data from 25 dwellings. Model uncertainty metrics demonstrate the transition from dynamic to steady state approximations as a function of time resolution. An optimal sampling frequency of 24 hours is found, providing quantitative evidence for assumptions made in previous research. It is shown that multiple uncertainty metrics are required to properly characterise the uncertainty profile, and that using the maximum resolution of data available may counter-intuitively increase model uncertainty.
Post-translational Modifications (PTMs), from a Cancer Perspective: An Overview

Studies on post-translational modifications (PTMs) have grabbed attention of the scientific community worldwide, its role in pathogenesis of cancer and prognostic biomarkers associated with cancers. However, unraveling the specific role of PTMs in carcinogenesis or in predictive biomarkers requires holistic understanding of the cancer types and associated mechanisms. Manifestation of cancer is complex and involves multiple steps including modifications at the levels of genes, associated proteins and signaling pathways. Biomarkers, as a prognostic marker, are critical in deciding efficacy of the clinical outcomes in malignancies. Growing evidence suggests that several biomarkers that are post-translationally modified play important role in human cancers. In the current review, few of such biomarkers and targets that are post-translationally modified and are associated with carcinogenesis are collated and analyzed to provide a bird’s eye view of their role in cancer types. Such analysis will help in understanding the pathogenesis and the precise role of biomarkers in designing better therapeutic interventions for different cancer types.
Elliptic equations and rearrangements

© Scuola Normale Superiore, Pisa, 1976, tous droits réservés. L’accès aux archives de la revue « Annali della Scuola Normale Superiore di Pisa, Classe di Scienze » (http://www.sns.it/it/edizioni/riviste/annaliscienze/) implique l’accord avec les conditions générales d’utilisation (http://www.numdam.org/conditions). Toute utilisation commerciale ou impression systématique est constitutive d’une infraction pénale. Toute copie ou impression de ce fichier doit contenir la présente mention de copyright.
Preferences Involved Comprehensive Evaluation in Educational Management and Decision Making

Evaluation functions are very crucial in educational comprehensive evaluation. This study summarizes some classical evaluation functions and shows their usage in Pedagogic evaluation applications. The study also presents and illustrates some hybrid evaluation function with some types of preferences of decision makers involved. Some illustrations with examples show that different types of preferences can embody both educators’ teaching experience and their optimism/pessimism decision attitudes. Therefore, the analyses in this study can help first line teachers select suitable, flexible and reasonable models for their practical educational comprehensive evaluations.
The role of the solar irradiance variability in the evolution of the middle atmosphere during 2004–2009

Recent measurements by the Spectral Irradiance Monitor (SIM) and the Solar Stellar Irradiance Comparison Experiment (SOLSTICE) onboard the Solar Radiation and Climate Experiment satellite have revealed the spectral solar irradiance (SSI) changes in the ultraviolet between 2004 and 2009 to be several times higher than it was shown by all previous SSI measurements and reconstructions. In this paper, we simulate the O3, OH, and temperature responses to solar irradiance variability using four different SSI data sets trying to define which one gives the best agreement between the simulated and observed responses. First, we apply the 1‐D radiative‐convective model with interactive photochemistry to determine the regions of the atmosphere where the O3, OH, and temperature are most sensitive to the spectrum discrepancies between the different SSI data sets. As the comparison with observations can be only made taking into account dynamics and all known forcings of the atmosphere, we then apply the 3‐D chemistry‐climate model SOCOL to simulate the atmosphere evolution from May 2004 to February 2009. We compare the modeled OH, O3, and temperature changes with atmospheric data measured by several space instruments. Overall, the comparison shows that the atmospheric changes simulated with the 3‐D SOCOL model driven by the SIM and SOLSTICE SSI are closest to the atmospheric measurements.
Fruit quality of Brazilian genotypes of feijoa at harvest and after storage

The objective of this work was to evaluate the physicochemical attributes and vitamin C contents of fruits of five Brazilian genotypes of feijoa (Acca sellowiana), at harvest and after cold storage. The Alcântara, Mattos, Helena, and Nonante cultivars, as well as accession 2316, were studied. The assessed attributes were: fresh mass loss, titratable acidity, soluble solids contents, soluble solids contents/titratable acidity ratio, pH, skin and flesh color, texture, and vitamin C contents (skin and flesh). After storage, there were reductions of 2.9% in soluble solids contents, of 32.2% in titratable acidity, and of approximately 85% in texture attributes, besides increases of 36.3% in the soluble solids contents/titratable acidity ratio and of 21.7% in the pH of fruits. The vitamin C content in the skin was higher than that in the flesh, and increased in both skin and flesh after storage. 'Alcântara' fruits have the highest contents of vitamin C in the skin and flesh. Fruits of 'Nonante' and 'Mattos' show better preservation of the texture attributes, and fruits of 'Nonante', the lowest levels of flesh browning during storage.
Interactive comment on “ Extreme temperature days and potential impacts in Southern Europe ” by A

As forestry engineer in the Canary Islands, the effect of HTDs on population and their influence in wildfires (both start and propagation) becomes an extremely interesting dataset for our seasonal planning and for our way of facing our future in emergency management. Although we do not have such a study on our region yet, we′ve been encouraged by this paper to set a low-profile imitation, checking HTD25 and HTD(95), and also advected african dust phenomena. We′ll use this study as a base to build our one for Western Canaries, and we′ll surely try to share our conlusions with you for extra opinions.
PCBs in the Arctic atmosphere: determining important driving forces using a global atmospheric transport model

Abstract. We present a spatially and temporally resolved global atmospheric polychlorinated biphenyl (PCB) model, driven by meteorological data, that is skilled at simulating mean atmospheric PCB concentrations and seasonal cycles in the Northern Hemisphere midlatitudes and mean Arctic concentrations. However, the model does not capture the observed Arctic summer maximum in atmospheric PCBs. We use the model to estimate global budgets for seven PCB congeners, and we demonstrate that congeners that deposit more readily show lower potential for long-range transport, consistent with a recently described "differential removal hypothesis" regarding the hemispheric transport of PCBs. Using sensitivity simulations to assess processes within, outside, or transport to the Arctic, we examine the influence of climate- and emissions-driven processes on Arctic concentrations and their effect on improving the simulated Arctic seasonal cycle. We find evidence that processes occurring outside the Arctic have a greater influence on Arctic atmospheric PCB levels than processes that occur within the Arctic. Our simulations suggest that re-emissions from sea ice melting or from the Arctic Ocean during summer would have to be unrealistically high in order to capture observed temporal trends of PCBs in the Arctic atmosphere. We conclude that midlatitude processes are likely to have a greater effect on the Arctic under global change scenarios than re-emissions within the Arctic.
A Broadband Left-Handed Metamaterial Microstrip Antenna with Double-Fractal Layers

This paper proposes a microstrip patch antenna based on the left-handed metamaterial concept, using planar periodic geometry, which results in improved characteristics. This periodic geometry is derived from fractal shapes, which have been widely used in antenna engineering. The metamaterial property was obtained as a result of the double-fractal structure on both the upper and the bottom sides of the antenna. The final structure has been optimized to enhance bandwidth, gain, and radiation characteristics of the microstrip antenna. This combination significantly improved antenna performance; our design could support an ultrawide bandwidth ranging from 4.1 to 19.4 GHz, demonstrating higher gain with an average value of 6 dBi over the frequency range and a peak of 10.9 dBi and a radiation capability directed in the horizontal plane of the antenna.
An Innovative Pansharpening Method Based on MRF Strategy

An innovative pansharpening method is proposed to selectively extract more useful information from the original images to produce a new image with higher resolution information. The standard PCA is employed as a decorrelation tool to separate the spectral and spatial information in MS images. In order to reduce the spectral distortion of fused image, we decompose the first principal component (PC1) of multispectral (MS) images and panchromatic (PAN) images using nonsubsample shearlet transform (NSST) to achieve effective detailed information; a novel energy function, including the inter- and intrainformation between subbands, has been established to take full account of the local dissimilarity between MS and PAN images, and the reasonable coefficients are selectively chosen based on Markov random field (MRF). It is found that the simulated image by the new method is more close to the real image and more clear and with more detailed information compared with other popular methods reported recently, which means that our new method can effectively improve the efficiency and quality during the fusion image process.
The applicability of patient-reported outcomes in primary care : Monitoring of patients with asthma or chronic obstructive pulmonary disease

Aims of the thesis: The general objective of this project was to identify and to some extent remove obstacles in the incorporation of disease-specific quality of life and/or health-status assessments in the management of asthma and COPD patients in primary care. The measurement properties, the design and the administrative complexity of the instruments at hand have been scrutinized with the intent to make it possible for primary care to integrate a patient perspective in the treatment and monitoring of asthma and COPD. Methods: Psychometric analysis of the measurement properties and performance of the questionnaires ACQ and MiniAQLQ in primary care (paper I). Psychometric analysis of the measurement properties and the performance of the CCQ in primary care (paper II). A cluster randomised study of the influence of information and monitoring on asthma control. Analysis were made of group differences on the ACQ and the MiniAQLQ and estimates of responsiveness of both questionnaires were calculated (paper III) . Semi-structured interviews with patients with COPD with an extended version of the SEIQoL-DW (paper IV). Results: The Mini-AQLQ and ACQ correlated well with the criterion measure AQLQ(S). Reliability coefficients were good. Both questionnaires detected improvement or deterioration of patients at the group level (paper I). Overall correlations between the criterion measure SGRQ and CCQ were strong for all patients with clinical COPD (0.84). These correlations between CCQ and SGRQ were moderate to good, regardless of COPD severity. Reliability was good but not sufficient for individual level assessment (paper II). ACQ score changes differed between the study groups (p < 0.05). In the intervention group, these changes in asthma control were close to clinical significance (MID 0.5). Both groups improved in disease-specific quality of life scores. For the intervention group, which changed the most (p < 0.05), the change exceeded the threshold for the MID. (paper III). The cue areas rated as most important with the generic part was the subjects' own health and relation to partner and family. The cue areas rated most important with the disease-specific part was; worries about own health, and independence. When comparing the results of the SEIQoL with standardised questionnaires content it seems as several areas of importance as nominated by the COPD patients are not addressed in standardised questionnaires, especially the areas of social life and mental health (paper IV). Conclusions: The asthma-specific instruments ACQ and MiniAQLQ exhibited measurement properties that allow use on an individual level in primary care. The CCQ did not meet the measurement requirements set for use on an individual level. Further, development is proposed in order to enhance performance of the instrument.
Testing gravity on cosmological scales with cosmic shear, cosmic microwave background anisotropies, and redshift-space distortions

We use a range of cosmological data to constrain phenomenological modifications to general relativity on cosmological scales, through modifications to the Poisson and lensing equations. We include cosmic microwave background anisotropies measurements from the Planck satellite, cosmic shear from CFHTLenS and DES-SV, and redshift-space distortions from BOSS data release 12 and the 6dF galaxy survey. We find no evidence of departures from general relativity, with the modified gravity parameters constrained to $\Sigma = -0. 01_{-0.04}^{+0.05}$ and $\mu = -0.06 \pm 0.18$. We also forecast the sensitivity of the full five-year Dark Energy Survey and of an LSST-like experiment to those parameters, showing a substantial expected improvement in the constraint on $\Sigma$.