Miracle-dz/UniFAR-FTUs huggingface dataset:
On “Feeling Right” in Cultural Contexts

Whether one is in one’s native culture or abroad, one’s personality can differ markedly from the personalities of the majority, thus failing to match the “cultural norm. ” Our studies examined how the interaction of individual- and cultural-level personality affects people’s self-esteem and well-being. We propose a person-culture match hypothesis that predicts that when a person’s personality matches the prevalent personalities of other people in a culture, culture functions as an important amplifier of the positive effect of personality on self-esteem and subjective well-being at the individual level. Across two studies, using data from more than 7,000 individuals from 28 societies, multilevel random-coefficient analyses showed that when a relation between a given personality trait and well-being or self-esteem exists at the individual level, the relation is stronger in cultures characterized by high levels of that personality dimension. Results were replicated across extraversion, promotion focus, and locomotive regulatory mode. Our research has practical implications for the well-being of both cultural natives and migrants.
Linkages between the South and East Asian Monsoon Water Vapor Transport during Boreal Summer

This study provides a water vapor transport (WVT) perspective on the linkages between the South Asian and East Asian summer monsoons (SASM and EASM) and indicates two robustly coupled modes of the vertical integrated WVT (VIWVT) over the two monsoons that accounts for above 90% of the total squared covariance fraction. The first coupled mode [singular value decomposition mode 1 (SVD1 mode)] depicts a meridional linkage between the meridional dipole VIWVT anomalies over both the SASM and EASM, while the second coupled mode (SVD2 mode) illustrates a zonal connection of an anomalous cyclonic/anticyclonic VIWVT over the SASM and a zonal wavelike VIWVT over the EASM. The SVD1 mode is linked through the anomalous subtropical high over the western North Pacific (WNPSH) and is primarily associated with the transition phase of El Niño/La Niña (ENSO) and simultaneous Indian Ocean basin mode (IOBM) SST warming/cooling. The meridional connection of the VIWVT in the SVD1 mode experienced a clear intensification since the late 1970s that may be attributed to the strengthened impacts of the ENSO/IOBM on the EASM and SASM after the late 1970s. The SVD2 mode is connected by the circumglobal teleconnection (CGT) pattern and related to the developing phase of ENSO and summer North Atlantic tripole (NAT) SST anomalies. The zonal VIWVT connection in SVD2 mode is strongly modulated by the SASM–CGT connections and reveals significant weakening since the late 1970s but reintensifies after the early 1990s. This may be associated with the weakened ENSO–SASM relationship after the late 1970s and interdecadal decreasing of the all Indian summer rainfall since the early 1990s.
Kinetics of allopurinol and its metabolite oxypurinol after oral administration of allopurinol alone or associated with benzbromarone in man. Simultaneous assay of hypoxanthine and xanthine by gas chromatography‐mass spectrometry

Summary— Allopurinol, oxypurinol, hypoxanthine and xanthine were assayed simultaneously using a highly specific method combining gas chromatography and mass spectrometry. Two hypo‐uricaemic prescriptions were compared: i) 300 mg of allopurinol (AL); and ii) 100 mg of allopurinol plus 20 mg of benzbromarone (AL + BZB). When administered acutely, their effects on blood uric acid levels were similar. Analysis of the pharmacokinetic parameters of allopurinol and its metabolite after each treatment showed dose‐linearity for the metabolite but not for the drug itself. The area under the concentration time curve for allopurinol was 40.3 ± 9.3 μmol 1−1 h after AL, against 8.4 ± 3.9 μmol−1 h after AL + BZB, while for oxypurinol it was 948.0 ± 125.4 μmol 1−1 h after AL and 285.2 ± 77.9 μmol 1−1 h after AL + BZB. The difference in dosage form may partly account for this difference, but the benzbromarone also seems to be involved. Its role on the blood uric acid lowering action of the drug association is complex. Although benzbromarone appreciably favors the elimination of oxypurinol, which should result in a weakening of its hypo‐uricaemic action, this is offset by enhanced elimination of hypoxanthine and xanthine. Renal clearance of xanthine was significantly increased under AL + BZB (173.1 ± 65.6 ml/min against 112.2 ± 32.9 ml/min after AL). Similarly, blood xanthine levels were proportionately higher in the presence of benzbromarone. The action of the two agents may thus be synergistic and not antagonistic, a pharmacological justification for the therapeutic use of this drug association.
[Digital inflection rigidometry in the study of erectile dysfunction. A new technique].

OBJECTIVES A device for reliable measurement of penile axial rigidity has been sought for some time. Three years of research have led to the development of the Digital Inflexion Rigidometer. The new technique and the results obtained are described herein. METHOD The Digital Inflexion Rigidometer was utilized in 150 patients that had consulted for erectile dysfunction of different etiologies. RESULTS In 60% of the cases, the Rigiscan recorded a circumferential rigidity of 60-70%; However, the Digital Inflexion Rigidometer showed penile axial rigidity to be insufficient for coitus. Fourteen cases with psychogenic erectile dysfunction had an axial rigidity greater than 600 gms, a difference of more than 300 gms in comparison with the recorded clinical postinjection rigidity. Home Digital Inflexion Rigidometry of 14 cases suspected of having venous leakage showed a difference of 300 to 500 gms between the first and second measurement (performed after taking 3 or 4 steps). CONCLUSION In our view, the Digital Inflexion Rigidometer is a useful diagnostic tool in erectile dysfunction which permits precise and painless measurement of the penile axial rigidity, relative intracavernosal pressure and penile temperature.
Genomic evaluation using SNP- and haplotype-based genomic relationship matrices in a closed line of Duroc pigs.

A simulation analysis and real phenotype analysis were performed to evaluate the impact of three different relationship matrices on heritability estimation and prediction accuracy in a closed-line breeding of Duroc pigs. The numerator relationship matrix (NRM), single nucleotide polymorphism (SNP)-based genomic relationship matrix (GRM) (GS ), and haplotype-based GRM (GH ) were applied in this study. We used PorcineSNP60 genotype array data (38 114 SNPs) of 831 Duroc pigs with four selection traits. In both heritability estimation and prediction accuracy, the accuracy depended on the number of animals with records. For heritability estimation, a large difference in the results among three relationship matrices was not shown, but the trend of the estimated heritabilities between GRMs, that is GS < GH , was shown in this population. For the accuracy of prediction values in test animals, the accuracies of prediction values obtained by two GRMs were higher than that by the NRM in this population. The accuracies obtained by GRMs using animals with no records were lower than that by the NRM using animals with their performance records, but were close to that by the NRM using animals with full-sib testing records.
Experimental Autoimmune Inflammatory Myopathy

We report an experimental model of autoimmune inflammatory myopathy. Splenic cells from two inbred murine strains (BALB/c and SJL/J) are activated (immunized) in vitro by co-culture with their respective syngeneic skeletal muscle myotubes. Subsequent injection of the activated splenocytes with or without B. pertussis into the respective syngeneic hosts results in inflammatory myopathy in the SJL/J mice but never in the BALB/c mice. The muscle inflammation is very similar in appearance to human autoimmune inflammatory myopathies. The myositis is not effector cell-skeletal muscle specific because splenocytes activated by co-culture with smooth muscle will also elicit skeletal muscle lesions. Both strains of skeletal muscle appear to express class II (Ia) antigens and the splenocytes from both strains appear to be equally activated. Thus we postulate that the difference in the expression of myositis between the two strains is in the effector phase of the disease. Since SJL/J mice have vasoactive amine sensitive vascular systems and BALB/c do not, it is likely that activated splenocytes emigrate from muscle microvessels in the SJL/J strain whereas they cannot do so in the BALB/c strain. The most significant contribution of this model may be in its potential for addressing a sine qua non of cellular autoimmune disease, i.e. lymphocyte migration from the vascular compartment into the target tissue. Finally, the data support a cellular more than a humoral pathogenesis in this model.
Durch Rotaviren verursachte Gastroenteritiden in Deutschland

Zusammenfassung Rotaviren sind auch heute noch weltweit die häufigste Ursache von schweren Durchfallerkrankungen im Säuglings- und Kleinkindesalter. Schätzungen gehen von weltweit 111 Millionen Infektionen, 25 Millionen ambulanten Behandlungen und 440 000 Todesfällen bei Kindern unter 5 Jahren aus. Impfstoffe gegen Rotaviren sind seit 2006 in Europa zugelassen. In Deutschland haben einige Bundesländer eine Impfempfehlung schon vor der generellen Empfehlung durch die STIKO im Jahre 2013 ausgesprochen. Valide epidemiologische Daten zur Rate der Hospitalisierungen bei Kindern und den möglichen Auswirkungen der Impfempfehlungen sind rar. Eine Analyse der Abrechnungsdaten aller stationären Fälle bei Kindern von 0–10 Jahren zeigt, dass es im Mittel jährlich zu 25 440 Hospitalisierungen aufgrund einer durch Rotaviren verursachten Gastroenteritis kommt. 8,91 % aller stationären Aufenthalte waren durch eine akute Gastroenteritis bedingt. Vergleicht man die Raten der Hospitalisierungen vor und nach der Impfempfehlung, so lassen sich auch nach kurzer Zeit schon erste positive Effekte beobachten.
Where is the record we have lost in information

The management guru, Peter Drucker, believed that “Every task of a developed society requires management”. This is especially true of recordkeeping. The dictionary definition of management is “the act, manner, or practice of managing, handling, supervision, or control”. The basic premise of records management in ISO 15489 infers exactly this; it is all about the control, handling, supervision, and organisation of records. Today we can reformat, remix and ‘mashup’ information, and create composite information objects containing numerous different formats, such as video clips, text, and static images. These may result in the creation of a complex record. At the same time organisations are still producing relatively simple records. How many of these records, regardless of complexity, are managed effectively to meet the needs of the specific organisation in a specific industry sector? How many of these organisational records become lost in the information fog? Is this something records and information managers should be concerned about? Information growth is exponential. A simple Internet search provides much information about the rate and scale of this growth. For example, studies into information growth carried out by the University of California, estimate that information increases at a rate of more than 30% a year. How does this impact the average organisation, its information, its records and its recordkeepers? Are records in danger of being lost and are recordkeepers in danger of becoming marginalised, as Thibodeau suggested, because of the computing power that now exists and the sheer amount of information that flows through even the smallest organisation? Should we be questioning whether the ISO standard and indeed the concept of a ‘record’, is relevant in the Web 2.0 (soon to be Web 3.0) world? Are those characteristics which define ‘recordness’ still relevant in this environment? The medium might be somewhat changeable but what of the message? This paper highlights some of the problems recordkeepers are faced with today and argues that the concept of a ‘record’ and the need to ‘manage’ it are as valid in the Web 2.0 world as they were in the mid 1990s when Australians developed the first recordkeeping standard.
Wireless Clock Distribution System Using an External Antenna

A compact wireless clock distribution system with an external planar array antenna which can provide phase and amplitude distributions suitable for synchronizing circuits over a 35-mm diameter circular area at 3 GHz is proposed. The computer systems using this wireless clock distribution can have a comparable form factor as systems using a conventional clock network. The system is composed of a transmitter with an off-chip antenna, and multiple clock receivers with on-chip antennas distributed over an integrated circuit or over multiple ICs. The transmitter, which was fabricated in a 130-nm CMOS process, generates a 17-GHz clock signal which is periodically amplitude-modulated in order to initialize all of the receivers' clock dividers to the same clock phase. Besides increasing the synchronization area, this wireless approach effectively eliminates the dispersion problem in conventional clock networks. The experimental results presented show the feasibility and potential benefits of the wireless clock distribution system using an external antenna.
Diclazuril and equine protozoal myeloencephalitis (EPM): a clinical report.

Equine protozoal myeloencephalitis (EPM) is a nervous system disease caused by the protozoan Sarcocystis neurona. The clinical syndrome caused by the disease can have a variety of presentations. Classically, horses present with asymmetric ataxia and weakness defined by multifocal central nervous system lesions. Successful management of this disease has been frustrated by failure of treatment success and by relapse after withdrawal of therapy. Diclazuril is a triazine derivative used in the prophylaxis of coccidiosis in poultry and experimentally in lagamorphs for coccidiosis (Vanparijs et al. 1988, 1989; McDougald et al. 1991). It has been evaluated for the treatment of isosporiasis and cryptosporidiosis in AIDS patients (Kayembe et al. 1989; Menichetti et al. 1991; Limson-Pobre et al. 1995) It has also been used, to a limited extent, to treat experimentally induced Toxoplasma gondii encephalitis in mice (Lindsay et al. 1995). These observations suggest that triazine derivatives may be useful in the treatment of diseases such as EPM that are caused by similar organisms. The chemical structure of diclazuril is shown with other triazine derivatives in Figure 1. The triazine ring is present in all of the compounds; a benzeneacetonitrile group (benzene ring with an acetonitrile group attaching it to the centre ring structure) in all compounds except toltrazuril; and all compounds are correctly termed triazinones due to the presence of the ketone groups on the triazine ring structure (Fleeger 1997). Recent research utilised oral diclazuril (Clinacox) daily for 3 weeks to treat a horse with severe neurological impairment. This treatment resulted in significant clinical improvement (Granstrom et al. 1997). Research found that a closely related compound, toltrazuril, was well absorbed after oral administration to horses (Tobin et al. 1997). Recent research suggests that triazines may be selectively toxic for apicomplexans due to a chlorophyll a D1 complex that serves as the target site for such agents (Hackstein et al. 1995). This site is thought to be conserved in apicomplexans and to be absent in mammals (Hackstein et al. 1995). Therefore, triazine derivatives may exhibit selective toxicity to these parasites while causing few or no appreciable side effects in an equine patient. Based on encouraging preliminary evidence of bioavailability, selective toxicity and clinical efficacy, a clinical investigation of the efficacy of diclazuril for the treatment of EPM was initiated. The purpose was to: 1) evaluate the clinical efficacy of this compound in the treatment of EPM; 2) establish an effective daily dosage and treatment duration; 3) estimate the rate of relapse at 6 months; and 4) provide preliminary information on the occurrence of adverse effects associated with treatment.
Up-To-Crash: Evaluating Third-Party Library Updatability on Android

Buggy and flawed third-party libraries increase their host app's attack surface and put the users' privacy at risk. To avert this risk, libraries have to be kept updated to their newest versions by the app developers that integrate them into their projects. Recent researches revealed that the prevalence of outdated third-party libraries in Android apps is indeed a rampant problem, but also suggested that there is a great opportunity for drop-in replacements of outdated libraries, which would not even require cooperation by the app developers to update the libraries. However, all those conclusions are based on static app analysis, which can only provide an abstract view. In this work, we extend the updatability analysis to the runtime of apps. We implement a solution to update third-party libraries with drop-in replacements by their newer versions. To verify the feasibility of this developer-independent update mechanism, we dynamically test 3,000 real world apps for 3 popular libraries (78 library versions) for runtime failures stemming from incompatible library updates. To investigate the updatability of libraries in-depth, exploration enhanced dynamic testing is adopted to monitor the runtime behaviors of 15 apps before and after library updating. From our test, we find that the prior reported updatability rate is under real conditions overestimated by a factor of 1.57-2.06. Through root cause analysis, we find that the underlying problems prohibiting easy updates are intricate, such as deprecated functions, changed data structures, or entangled dependencies between different libraries and even the host app. We think our results not only put a more realistic light on the library updatability problem in Android, but also provide valuable insights for future solutions that provide automatic library updates or that try to support the app developers in better maintaining their external dependencies.
Real-time hand gesture feature extraction using depth data

In this paper, a novel method is proposed to extract hand gesture features in real-time from RGB-D images captured by the Microsoft's Kinect. A contour length information based de-noise method is introduced for the hand gesture smooth segmentation and edge contour extraction. In addition, a finger earth mover's distance algorithm is applied with a novel approach to locate the palm image and extract fingertip features. Especially the proposed Lasso algorithm can effectively extract the fingertip feature from a hand contour curve correctly with excellent real-time performance.
Detection of D‐penicillamine in skin lesions in a case of dermal elastosis after a previous long‐term treatment for Wilson's disease

Skin adverse events associated with D‐Penicillamine (DPA) are common and multi‐faceted, although the presence of DPA or its metabolites has never been documented in the skin, because of inherent difficulties in determining its tissue levels. Thus, the association between DPA and DPA‐related dermatoses has been only hypothesized on the basis of careful history, clinical observation and typical histopathological findings.
Prospective Study on Suicidal Ideation Among Japanese Undergraduate Students: Correlation with Stressful Life Events, Depression, and Depressogenic Cognitive Patterns

The present study examines the effects of stressful life events, depression, and depressogenic cognitive patterns on suicidal ideation in 500 Japanese undergraduate students. The above factors were assessed at baseline (T1) and two weeks later (T3). At T1, structural equation modeling confirmed that (1) cognitive patterns and depression, but not stressful life events, influence suicidal ideation, and (2) cognitive patterns also influence suicidal ideation through depression. These findings were confirmed in a longitudinal analysis. The results suggest that the effects of stressful life events on suicidal ideation are indirect and are mediated by depressogenic cognitive styles and depressed mood.
Reducing residual risk: modern pharmacochemistry meets old-fashioned lifestyle and adherence improvement

Despite remarkable advances in identifying and managing coronary heart disease, the global burden of cardiovascular (CV) risk and levels of undetected, subclinical heart disease remain enormous. Substantial numbers of patients do not reach their therapeutic goals, others are unable to tolerate the treatments, half may fail to adhere to their programs, and in those who do attain their targets, major cardiovascular events may continue. Well-known risk factors, such as obesity and diabetes, have now gained the upper hand, with no evidence-based remedy capable of reversing this trend. All told, less than 1% of American adults and adolescents qualify for ideal CV health; world-wide, the growing prevalence of CV risk factors in children is imposing. A number of novel emerging drug therapies are in development, some recently approved for use in patients with familial hypercholesterolemia. Hopefully, they will contribute significantly to the current therapeutic armamentarium. However, for meaningful improvement in total and residual CV risk, an optimal mix of all available modalities will likely be necessary, including earlier and more effective prevention, aggressive medical care, revascularization and device implantation, judicious use of novel agents, and reengineering of the environment.
Estimation of new Similarity Measures for existing frameworks over Time for tracking Community structure in Online Social Network

Many real-world social networks are intimately organized according to a community structure. Most social networks are dynamic and connections between people change naturally overtime. Researchers have begun to consider the problem of tracking the formation of groups of users in social network. The situation is complicated by the fact that subgroups may split or merge, so that cohesiveness is not necessarily a property of a single subgroup, but may sometimes relate to a family of one or more related subgroups. However, in general, cohesive families of subgroups at one time period should be similar to corresponding subgroups at a different time period. Similarity is a topic that has received attention in a wide variety of scientific fields and a number of approaches are available for the measurement of similarity. This paper describes an efficient way for finding similarity in subgroups or clusters and tracking community which persist over time in dynamic networks.
Privacy Preserving Query Processing in the Cloud

Nowadays, cloud data outsourcing provides users and companies with powerful capabilities to store and process their data in third-party data centers. However, when a user stores her sensitive data in a public cloud, they becomes vulnerable to several attacks, e.g., from the employees of the cloud provider. One solution for protecting the user data against attacks is to encrypt the data before sending them to the cloud servers. Then, the challenge is to answer user queries over encrypted data. In this paper, we present a summary of our initial results in processing top-k k queries on encrypted data.