Miracle-dz/UniFAR-FTUs huggingface dataset:
Etude de la synchronisation et de la stabilité d’un réseau d’oscillateurs non linéaires. Application à la conception d’un système d’horlogerie distribuée pour un System-on-Chip (projet HODISS).

Le projet HODISS dans le cadre duquel s'effectue nos travaux adresse la problematique de la synchronisation globale des systemes complexes sur puce (System-on-Chip ou SOCs, par exemple un multiprocesseur monolithique). Les approches classiques de distribution d'horloges etant devenues de plus en plus obsoletes a cause de l'augmentation de la frequence d'horloge, l'accroissement des temps de propagation, l'accroissement de la complexite des circuits et les incertitudes de fabrication, les concepteurs s’interessent (pour contourner ces difficultes) a d'autres techniques basees entre autres sur les oscillateurs distribues. La difficulte majeure de cette derniere approche reside dans la capacite d’assurer le synchronisme global du systeme. Nous proposons un systeme d'horlogerie distribuee base sur un reseau d’oscillateurs couples en phase. Pour synchroniser ces oscillateurs, chacun d'eux est en fait une boucle a verrouillage de phase qui permet ainsi d'assurer un couplage en phase avec les oscillateurs des zones voisines. Nous analysons la stabilite de l'etat synchrone dans des reseaux cartesiens identiques de boucles a verrouillage de phase entierement numeriques (ADPLLs). Sous certaines conditions, on montre que l'ensemble du reseau peut synchroniser a la fois en phase et en frequence. Un aspect majeur de cette etude reside dans le fait que, en l'absence d'une horloge de reference absolue, le filtre de boucle dans chaque ADPLL est pilote par les fronts montants irreguliers de l'oscillateur local et, par consequent, n'est pas regi par les memes equations d'etat selon que l'horloge locale est avancee ou retardee par rapport au signal considere comme reference. Sous des hypotheses simples, ces reseaux d'ADPLLs dits "auto-echantillonnes" peuvent etre decrits comme des systemes lineaires par morceaux dont la stabilite est notoirement difficile a etablir. L'une des principales contributions que nous presentons est la definition de regles de conception simples qui doivent etre satisfaites sur les coefficients de chaque filtre de boucle afin d'obtenir une synchronisation dans un reseau cartesien de taille quelconque. Les simulations transitoires indiquent que cette condition necessaire de synchronisation peut egalement etre suffisante pour une classe particuliere d'ADPLLs "auto-echantillonnes".
Etude des systèmes dynamiques basés sur la décomposition orthogonale aux valeurs propres (POD) - application à la couche de mélange turbulente et à l'écoulement entre deux disques contra-rotatifs

On presente une etude des possibilites de la restitution qualitative de la dynamique d'un ecoulement pleinement turbulent en milieu ouvert, par un systeme dynamique d'ordre faible base sur la decomposition orthogonale (pod). Cette etude est menee principalement a partir de donnees experimentales, obtenues anterieurement, d'un ecoulement de couche de melange plane turbulente incompressible. On developpe, par projection de galerkin des equations du mouvement sur les fonctions propres determinees par la pod, un systeme dynamique temporel constitue par des equations differentielles ordinaires. Le nombre de degre de liberte est alors reduit pour ne retenir que le premier mode de la decomposition orthogonale, le nombre d'onde transversal nul et quelques nombres d'ondes longitudinaux. On compare alors l'influence, sur la dynamique de l'ecoulement, de differents modeles de fermeture des equations du mouvement. On montre que la fermeture par un champ moyen de vitesse constant permet de retrouver le mode le plus instable de la couche de melange. Aucune modelisation ne se montrant reellement satisfaisante a partir des donnees experimentales, on utilise alors des donnees numeriques issues d'une simulation aux grandes echelles de l'ecoulement. Les resultats de cette etude sont encourageants, laissant croire qu'une modelisation de l'ecoulement par un systeme dynamique d'ordre faible est possible. Finalement, on teste, en utilisant des donnees provenant d'une simulation numerique directe d'un ecoulement entre deux disques contra-rotatifs a faible nombre de reynolds, la robustesse aux variations des parametres de l'ecoulement, de la modelisation par un systeme dynamique d'ordre faible base sur la pod. On montre, en particulier, que l'application de la methode des snapshots a des realisations de l'ecoulement prises a plusieurs valeurs du nombre de reynolds ameliore la representativite du systeme dynamique
The nature of virus‐like particles in the paraxial muscles of idiopathic scoliosis

Virus-like particles (VLP) have been identified by electronmicroscopy in the skeletal muscles (paraxials) of six cases of idiopathic scoliosis. These particles closely resembled VLP reported in the skeletal muscles in other conditions, e.g. Reye's syndrome, polymyositis, malignant hyperthermia, and chronic myopathy. We have shown by specific staining that these structures are composed of glycogen in a crystalline form. Using Coxsackie B infected tissue culture cells as a control we have shown that these viruses, which are of similar shape and size to the VLP, were unstained using this specific staining method.
Insider Threat detection using Isolation Forest

In contrast to the need for companies to get real time information about insider threats, there is a privacy and integrity based limitation of what the individual accepts as acceptable surveillance. This creates a problem since performing online surveillance would pose an infringement on the employees privacy and integrity. Therefore we present a model using Isolation Forest to solve this problem. We focus on analyzing the non-intrusive features in a real time, event based approach. We process our features using periodic features, which we have sta- tistically proven to be more effective than periodic features used with Isolation Forest. Our results show that by analyzing employees login and logout times, we can detect 76% of all insider threats while only falsely classify 7% of all nor- mal instances. The recall rate, which shows how complete the results are, is 76%.
Explicit Information Interferes with Implicit Motor Learning of Both Continuous and Discrete Movement Tasks After Stroke

A large portion of the rehabilitation experience after stroke relies on implicit learning. However, our understanding of how best to facilitate motor learning after stroke is limited by a paucity of research that has explored the interaction between explicit information and implicit learning across various task domains. Previously we reported that the delivery of explicit instructions disrupted implicit motor learning after stroke that involved the sensorimotor cortical areas or basal ganglia. The purpose of this study was to determine the robustness of these findings by determining whether they could be replicated with 2 motor tasks, one discrete and one continuous, employed by the same group of participants. Then individuals with stroke in the sensorimotor cortical areas (SMC), 10 with stroke in the basal ganglia (BG), and 10 age-matched healthy controls (HC) participated in this study. Each completed 3 days of practice of both a discrete implicit motor task (the serial reaction time task) and a continuous motor task (the continuous tracking task); all returned on a fourth day for retention tests. By random designation, participants were divided into either the explicit information (EI) or no explicit information (No-EI) groups. Consistent with previous results, we found that the response to explicit information after stroke was uniformly negative regardless of task or lesion location; both stroke groups demonstrated an interference effect of explicit information while the healthy control group did not. Strengthening these findings is the fact that the interference effect of explicit information was not task dependent. This point is particularly important for rehabilitation scientists as they instruct clients during various therapeutic tasks after stroke. Our data suggest that certain forms of explicit information delivered before task practice may not be as useful for learning as discovering the solution to the motor task with practice alone, and this is regardless of the type of task being learned.
Equilibrium exchange rate

V tejto diplomovej praci skumame realny efektivny rovnovažny výmenný kurz Slovenskej koruny založený na indexe spotrebiteľských cien a cien výrobcov. Model na urcenie behavioralneho rovnovažneho kurzu (BEER) použitý v tejto praci bol inspirovaný Alberola et al. (1999, 2002). Spravanie sa rovnovažneho kurzu je popisane pomocou produktivity a cistých zahranicných aktiv.
Using twin studies to label disease as genetic or environmental is inappropriate

EDITOR—The cover of the BMJ on 2 February poses the question “Rheumatoid arthritis: is it genetic? ” and answers “Probably not. ” Neither the question nor the response is valid. The Danish twin study on which this conclusion is based identified no concordant monozygotic twin pairs and only two concordant dizygotic pairs from a sample of 37 338.1 By modelling the reported numbers of confirmed cases of rheumatoid arthritis, we calculate that the study had 80% power to detect a …
Development a diagnostic pan‐dermatophyte TaqMan probe real‐time PCR assay based on beta tubulin gene

Early differentiation of dermatophytosis from other cutaneous mycoses is essential to avoid inaccurate therapy. DNA‐based techniques including real‐time PCR have increasingly been considered for detection of fungal elements in clinical specimens. In this study, after partial sequence analysis of beta tubulin (BT2) gene in 13 common and rare pathogenic dermatophyte species, a pan‐dermatophyte primer and probe set was designed in a TaqMan probe‐based PCR format. The sensitivity and specificity of the system was tested with 22 reference strains of dermatophytes, 234 positive clinical specimens, 32 DNA samples extracted from normal nails, several fungi other than dermatophytes and human DNAs. Analytical detection limit of the designed PCR on serially diluted DNAs of prepared recombinant plasmid indicated that only five molecules per sample are the minimum number for reliable detection by the assay. A total of 226 out of 234 (96.5%) DNAs extracted from clinical samples, but none of the 32 nail samples, from healthy volunteers were positive in PCR. The real‐time PCR targeted beta tubulin gene established in this study could be a sensitive diagnostic tool which is significantly faster than the conventional culture method and should be useful in the clinical settings, in large‐scale epidemiological studies and in clinical trials of antifungal therapy.
Simulation and Experimental Investigation of an Optimum UPQC with Minimum VA Loading

The paper deals with an optimized unified power quality conditioner (UPQC), which aims at the integration of series active and shunt active power filters with minimum VA loading of the UPQC. The series active filter is a dynamic voltage restorer (DVR), which regulates the voltage at the load end with minimum VA loading of the overall UPQC by voltage injection at optimum angle. The proposed scheme is validated by simulation and an experimental prototype in laboratory. Selected experimental results are reported along with analytical findings, which show the effectiveness of the proposed UPQC
Real-time spectroscopic ellipsometry study of the growth of amorphous and microcrystalline silicon thin films prepared by alternating silicon deposition and hydrogen plasma treatment.

The growth of amorphous and microcrystalline silicon (\ensuremath{\mu}c-Si) films prepared by alternating the deposition of hydrogenated amorphous silicon (a-Si:H) and hydrogen plasma exposure is studied by in situ spectroscopic ellipsometry. The deposition and etching sequences are clearly identified in the real-time ellipsometric trajectories. Insights into the growth of amorphous and microcrystalline silicon materials are obtained from a detailed study of the effects of varying the deposition and hydrogen plasma treatment times as well as the thickness dependence of the film composition. Indeed, we have found that the composition of amorphous and microcrystalline films slowly changes with the increasing film thickness. However, while a-Si:H films becomes porous and rough with the increasing number of cycles, \ensuremath{\mu}c-Si films become denser and their crystalline volume fraction increases. During growth, the transition from a-Si:H to \ensuremath{\mu}c-Si deposition occurs through an intermediate highly porous a-Si:H phase. We suggest that this porous phase is a key element in \ensuremath{\mu}c-Si nucleation, while both selective etching and chemical annealing have to be considered in the growth of the crystallites. Our results show that it is possible to increase the volume fraction of the crystalline phase by reducing the deposition time within one cycle or by increasing the hydrogen plasma treatment time.
Passively Q-Switched Ho,Pr:LiLuF4 Laser at 2.95 μm Using MoSe2

In this letter, we report a diode-end-pumped continuous wave (CW) and passively Q-switched Ho,Pr:LLF laser at 2.95 μm. A maximum CW output power of 98 mW was achieved. The highest output power of 58 mW was radiated with a pulse duration of 818.8 ns and a repetition rate of 71.05 kHz. Even shorter pulse duration of 731.5 ns was obtained at a minor output coupler transmission.
Prevalence of Streptococcus dysgalactiae subsp. equisimilis and S. equi subsp. zooepidemicus in a sample of healthy dogs, cats and horses

AIMS: To estimate the prevalence of β-haemolytic Lancefield group C streptococci in healthy dogs, cats and horses; to determine if frequent contact with horses was associated with isolation of these species from dogs and cats; and to characterise recovered S. equi subsp. zooepidemicus isolates by multilocus sequence typing. METHODS: Oropharyngeal swabs were collected from 197 dogs and 72 cats, and nasopharyngeal swabs from 93 horses. Sampling was carried out at the Massey University Veterinary Teaching Hospital, on sheep and beef farms or on premises where horses were present. All animals were healthy and were categorised as Urban dogs and cats (minimal contact with horses or farm livestock), Farm dogs (minimal contact with horses) and Stable dogs and cats (frequent contact with horses). Swabs were cultured for β-haemolytic Streptococcus spp. and Lancefield group C streptococcal subspecies were confirmed by phenotypic and molecular techniques. RESULTS: Of the 197 dogs sampled, 21 (10.7 (95% CI= 4.0–25.4)%) tested positive for S. dysgalactiae subsp. equisimilis and 4 (2.0 (95% CI=0.7–5.5)%) tested positive for S. equi subsp. zooepidemicus. All these isolates, except for one S. dysgalactiae subsp. equisimilis isolate in an Urban dog, were from Stable dogs. S. dysgalactiae subsp. equisimilis was isolated from one Stable cat. Of the 93 horses, 22 (23.7 (95% CI=12.3–40.6)%) and 6 (6.5 (95% CI=2.8–14.1)%) had confirmed S. dysgalactiae subsp. equisimilis and S. equi subsp. zooepidemicus isolation respectively. Isolation of S. dysgalactiae subsp. equisimilis from dogs was associated with frequent contact with horses (OR=9.8 (95% CI=2.6–72.8)). Three different multilocus sequence type profiles of S. equi subsp. zooepidemicus that have not been previously reported in dogs were recovered. CONCLUSIONS AND CLINICAL RELEVANCE: Subclinical infection or colonisation by S. equi subsp. zooepidemicus and S. dysgalactiae subsp. equisimilis occurs in dogs and further research on inter-species transmission and the pathogenic potential of these Lancefield group C streptococci is needed. Complete speciation of β-haemolytic streptococci should be recommended in clinical cases and the possible exposure to horses and their environment should be considered in epidemiological investigations.
Understanding programmatic TV advertising

ABSTRACT Television is undergoing tremendous technological developments, which will enable marketers to direct commercial messages to more specific audiences at the individual and/or household level. Traditional ways of buying TV advertising are being challenged by the programmatic approach, which originated with search and display ads, and uses data and technology and real-time auctions to automate transactions between buyers and sellers. We discuss the changes to TV that enable the rise of programmatic models and propose that its future success depends on the coordination and availability of three factors, abbreviated DAD: distribution, ad inventory and data. We also elaborate on the effects of media context and how the TV program environment matters for advertising effectiveness. Finally, we discuss the future of TV advertising and related research needs.
The Impact of Enterprise R&D Investment on Social Responsibility Performance Under the Role of Ownership Structure

The enterprises’ innovation and its fulfillment of social responsibility have increasingly become the focus of public attention. Based on observations of 2234 listed companies in China from 2009 to 2015, this paper analyzes the above relationship and the impacts of ownership structure on this relationship. Additionally, we analyze the impacts of ownership structure from two aspects: ownership concentration and ownership type. The following conclusions are drawn: First, there is a significant positive correlation between corporate R&D investment and social responsibility performance. Second, regarding this positive impact is more obvious for Non-state-owned listed companies than stateowned listed companies. Third, regarding this positive impact is more obvious for companies with low ownership concentration than companies with high concentration. Keywords—ownership concentration; ownership type; social responsibility; R&D investment
Complete Genome of Geobacter pickeringii G13T, a Metal-Reducing Isolate from Sedimentary Kaolin Deposits

ABSTRACT We used PacBio sequencing to assemble the genome of the pristine freshwater isolate Geobacter pickeringii G13T into a single 3,618,700-bp circular chromosome polished to 99.999% accuracy (quality value [QV], 50). This isolate shares several features with other Geobacter spp. , including genes for degradation of aromatics and an abundance of multiheme c-type cytochromes.
On time-switched space-time transmit diversity in MISO systems

We investigate the performance of time-switched space-time transmit diversity schemes applied to a wireless communication system with multiple antennae at the transmitter and single antenna at the receiver. A new method of analysis of time-switched transmit diversity schemes is presented which builds on an information theoretic equivalent channel and a generalized definition of diversity for coded systems. We show that coded time-switched Alamouti (1998) space-time block codes actually outperform all coded orthogonal space-time block codes which use more than two antennae. Cutoff rate analysis for modulated signals, proves their performance to be close to optimum in a range of code-rates, which is interesting for wireless communication.
Wearout or Weariness? Measuring Potential Negative Consequences of Online Ad Volume and Placement on Website Visits

The global importance of online advertising calls for a detailed understanding of consumer-specific responses to online ad repetitions. A key concern for advertisers is not only whether some consumers display degrees of “wearout” but also whether they can surpass a point at which additional exposures have a negative marginal effect: “weariness. ” The authors examine a large-scale advertising campaign aimed at driving viewers to a target website, which comprises more than 12,000 users across over 400 websites. These data are analyzed using a flexible discrete mixture specification that accommodates different response shapes over ad stock and timing and parcels ad viewers into response classes based on their internet usage metrics. The resulting classes display varying degrees of wearout, with one subgroup, accounting for about 24% of the sample, evincing weariness. The model also estimates differential publisher effectiveness, with the most effective publisher being nine times more effective than the one 26 places down. The authors demonstrate that the finding of weariness is robust to all the model’s main components, with one key exception: heterogeneity in users’ ad response. Analysis further suggests that an appropriate “profiling and capping” strategy can improve ad deployment by as much as 15% overall for these data.
Preliminary Demonstration of 1.0 V CMOS Imager with Semi-Pixel-Level ADC Based on Pulse-Width-Modulation Pixel Readout

We demonstrate low-voltage operation of a CMOS imager with an in-pixel large-gain comparator without degradation of the dynamic range by using a pulse-width-modulation scheme in pixel readout. Experimental results showed a dynamic range of 57 dB with a 1.0 V power supply voltage at the pixel array block, which demonstrates the possibility of low-voltage, single-power-supply operation of imagers fabricated with deep-submicron CMOS technologies.
Backing the horse or the jockey? Due diligence, agency costs, information and the evaluation of risk by business angel investors

This paper explores the argument that business angel investors are more concerned with managing and minimising agency risk than market risk. Based on data on the due diligence process from a survey of business angels in the UK, the paper concludes that business angels do view entrepreneur characteristics and experience as having the greatest impact on the perceived riskiness of an investment opportunity. Further, they emphasise personal and informal over formal sources of information in the due diligence process, and seek information on both the entrepreneur and the venture in determining valuation. Indeed, the reliance of business angels on short-term and subjective information to value investment opportunities leads to the conclusion that their approach to valuation is not a function of the conventional protocols of financial analysis, but of personal relations and assessment.
The mTOR Inhibitor Everolimus Induces Proteinuria and Renal Deterioration in the Remnant Kidney Model in the Rat

Background. Under certain circumstances the nonnephrotoxic, antiproliferative, immunosuppressive mammalian target of rapamycin (mTOR) inhibitors can cause renal deterioration and proteinuria after conversion from calcineurin inhibitors, especially in long-term renal transplant patients with low glomerular filtration rates. The mTOR inhibitors also show an impaired glomerular healing reaction during acute renal injury in experimental mesangial proliferative glomerulonephritis. In this study, everolimus treatment was investigated in a low nephron number model, the remnant kidney model in rats. Methods. The remnant kidney model was induced by uninephrectomy and infarction of 2/3 of the remaining kidney in 31 male Sprague-Dawley rats. Three days after disease induction, rats were randomly treated either with everolimus or vehicle. Changes in progression of renal disease were investigated by immunohistochemistry on days 22 and 38 after disease induction. Results. In the remnant kidney model, everolimus treatment worsened chronic disease progression as assessed by increased proteinuria, glomerulosclerosis, interstitial fibrosis, glomerular inflammation as well as decreased creatinine-clearance. This result was due to a markedly increased fraction of glomeruli with a defective glomerular architecture in the everolimus group. Everolimus apparently inhibited the chronic glomerular repair reaction via inhibition of the proliferative but not apoptotic activity of the glomerular endothelial and mesangial cells, which was associated with reduced glomerular vascular endothelial growth factor mRNA and protein. In contrast, the fraction of glomeruli with an intact glomerular architecture within the everolimus group showed clearly less glomerular enlargement compared to vehicle-treated nephrectomy rats. Conclusion. This study demonstrates potential mechanisms of mTOR inhibitor induced renal deterioration and proteinuria in the low nephron number remnant kidney model.