Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental Study of Sand Particle Deposition on a Film-Cooled Turbine Blade at Different Gas Temperatures and Angles of Attack

Particle deposition tests were conducted in a turbine deposition facility with an internally staged single-tube combustor to investigate the individual effect of the gas temperature and angle of attack. Sand particles were seeded to the combustor and deposited on a turbine blade with film-cooling holes at temperatures representative of modern engines. Fuel-air ratios were varied from 0.022 to 0.037 to achieve a gas temperature between 1272 and 1668 K. Results show that capture efficiency increased with increasing gas temperature. A dramatic increase in capture efficiency was noted when gas temperature exceeded the threshold. The deposition formed mostly downstream of the film-cooling holes on the pressure surface, while it concentrated on the suction surface at the trailing edge. Deposition tests at angles of attack between 10° and 40° presented changes in both deposition mass and distribution. The capture efficiency increased with the increase in the angle of attack, and simultaneously the growth rate slowed down. On the blade pressure surface, sand deposition was distributed mainly downstream of the film-cooling holes near the trailing edge in the case of the small angle of attack, while it concentrated on the region around the film-cooling holes near the leading edge, resulting in the partial blockage of holes, in the case of the large angle of attack.
Effects of Gradient Optimizer on Model Pruning

Deep convolutional neural networks deploy in applications are hindered by their large parameters and high computational cost. In this paper, we test different gradient optimizer’s effect on YOLOv3 model pruning. This is achieved by enforcing channel-level sparsity in YOLOv3 network. The model trained with Adam optimizer get 5× reduction in model size only after training 60 epochs.
Preventing PostPartum HemorrHage: WHy Quality imProvement matters

PostPartum HemorrHage is tHe leaDing Cause oF maternal DeatH WorlDWiDe More than half a million women die every year of complications related to pregnancy or childbirth. Postpartum hemorrhage (PPH)— unchecked uterine bleeding occurring after childbirth—is the leading cause of maternal deaths worldwide. PPH usually occurs unexpectedly and can lead to death in under two hours if untreated. In many developing countries a woman who begins to hemorrhage has limited or no access to health care that can save her life. Thus, preventing PPH is a critical strategy to reduce maternal mortality. Uterine atony, which occurs when uterine muscles fail to contract normally following birth, is the leading cause of PPH and can be prevented in a majority of cases through an evidence-based clinical practice known as active management of the third stage of labor (AMTSL). Yet, many health services worldwide fail to routinely deliver AMTSL, a gap that represents a major quality problem in maternal health care.
Characteristics of the Lipid Profile in Patients with Diabetes Mellitus and Chronic Kidney Disease

Abstract Background and aims Diabetes mellitus (DM) is one of the leading causes of end-stage chronic kidney disease (CKD). Patients with DM and CKD have a 10 or even 20 times higher cardiovascular risk (CVR) than the general population. Lipid metabolism disorders are more frequent in these patients, dyslipidemia being aggravated by the presence of hyperglycemia and insulin resistance. The main purpose of our study was to identify possible correlations between lipid profile parameters and altered renal function in patients with DM. We have also analyzed the correlations between lipid parameters, CKD, quality of glycemic control and CVR. Material and method: The study was performed on 2732 patients with DM which received medical treatment and care at the Center for Diabetes Timisoara, for a 6-month period from March to October 2016, 1508 women (55.2%) and 1224 men (44.8%), mean age 63.7 ± 9.1 (33-78) years and mean diabetes duration 12.4 ± 6.8 (6-33) years. The study group included 312 patients (11.4%) with T1DM and 2420 patients (88.6%) with T2DM. Results: The prevalence of CKD (GFR< 60 ml/min) was 12.5%. The levels of total cholesterol (TC), triglycerides (TG) and LDLc were significantly higher in the case of patients with DM and CKD (p<0.0001). Patients with CKD had twice the prevalence of ischemic heart disease and cerebrovascular disease when compared to patients without CKD. Peripheral artery disease was present in 16.9% of those with CKD and in 11% of those without CKD. Hypertension (HTN) was present in 91.8% of patients with CKD and in 67.1% of patients without CKD (GFR > 60 ml/min). Conclusion: Analyzed data showed a strong correlation between CKD, dyslipidemia and CVR in patients with DM. Impaired renal function was strongly correlated with age, duration of DM and weight status of these patients.
Diversity in Teams: Perceptions of Team Learning Behaviour in a Military Staff Exercise

The aim of this study is to analyse diversity in team learning behaviour between and among national respondents’ perceptions during a military staff exercise (CJSE). Edmondson’s team learning behaviour model is used as the theoretical basis of the study. The results showed statistically significant differences both between and among national respondents’ perceptions. The research results indicate that team leader coaching, team psychological safety, the importance of obtaining expert knowledge as well as pre-exercise training are perceived to be crucial for team learning behaviour. The study has theoretical and practical implications for a more nuanced understanding of the diversity of team learning behaviour in the context of a multinational military teamwork exercise and for working as a part of multinational temporal teams in particular.
Pertussis vaccine schedules across Europe

In August 2004, the United Kingdom (UK) National Health Service announced the introduction of a new five-combination vaccine against diphtheria, tetanus, pertussis, polio and Hib in the infant vaccination schedule: 2, 3 and 4 months (DTaP/IPV/Hib)
Hypertensiopotilaan lääkehoitoon sitoutuminen : systemaattinen kirjallisuuskatsaus

Hypertensio on lukuisten sairauksien riskitekijä ja yksi tärkeimmistä kuolleisuutta aiheuttavista tekijöistä. Verenpainelääkityksen käyttäjiä on Suomessa noin miljoona eli joka viides suomalainen. Heistä arviolta vain noin 40 % yltää hoitotavoitteeseen. Potilaan sitoutuminen sairautensa hoitoon on hoidon tuloksellisuuden keskeinen osatekijä. Tutkimuksen tarkoituksena oli koota systemaattisen kirjallisuuskatsauksen avulla tietoa hypertensiopotilaan lääkehoitoon sitoutumiseen yhteydessä olevista demografisista ja psykososiaalisista tekijöistä. Kirjallisuushaut tehtiin Medline-, CINAHL-, Medic-, Artoja Melinda –tietokantoihin, joiden tuloksina saatiin 1636 viitettä. Niistä valikoitui 37 tutkimusta vuosilta 2000–2017. Aineisto tiivistettiin deduktiivisesti teemoittelemalla. Tulosten mukaan demografisista tekijöistä vanhemmat ikäryhmät sitoutuivat nuorempia paremmin hypertension lääkehoitoon. Psykososiaalisista tekijöistä potilaan aktiivinen asenne sairautensa hoitoon, sen myöntäminen ja hyväksyminen olivat yhteydessä parempaan sitoutumiseen. Hypertension lääkehoitoon sitoutuminen koostuu useista tekijöistä. Psykososiaaliset tekijät ovat potilaan hoidon ja ohjauksen kannalta erityisen kiinnostavia, koska niihin voidaan vaiABSTRACT
Convenções de qualidade em queijos artesanais no Brasil, Espanha e Itália

Muitas vezes os alimentos artesanais são vistos pelos consumidores como sendo mais naturais e saudáveis e são valorizados devido a sua tradição, origem e sustentabilidade dos processos envolvidos. Os queijos artesanais representam bem essa categoria de alimentos, pois sua caracterização envolve o tipo de matéria-prima, o método de processamento, as características edafoclimáticas de onde são produzidos, as receitas utilizadas, a pequena escala de produção, as relações estabelecidas entre o produtor e o consumidor. No entanto, essas características estão balizadas por normas sanitárias que nem sempre conseguem ser atendidas pelos produtores, que acabam por realizar a venda informalmente. O objetivo deste artigo é demonstrar as diferenças existentes entre as concepções, práticas e estratégias de qualidade de queijos artesanais e o impacto da legislação sanitária sobre eles a partir de estudos de caso específicos de queijarias do Brasil, Espanha e Itália.
Insufficient intake of alpha-linolenic fatty acid (18:3n-3) during pregnancy and associated factors

Objetivo: Analisar a ingestao acidos graxos alfa-linolenico e identificar fatores associados a ingestao inadequada em duas coortes de gestantes acompanhadas trimestralmente. Metodos: Estudo de coorte com gestantes de baixo risco obstetrico (N=353) representativas das usuarias da rede publica de saude de um municipio paulista. Nos tres trimestres gestacionais foram coletados dois recordatorios alimentares de 24 horas. Analises descritivas do perfil lipidico da dieta foram processadas seguidas do teste de comparacoes multiplas. As diferencas, segundo trimestre gestacional, foram avaliadas pelo teste de diferenca de medias. Para avaliacao da adequacao do consumo foi utilizada a ingestao recomendavel. A associacao entre a adequacao da ingestao de acido alfa-linolenico e caracteristicas maternas foi investigada por meio de modelo de regressao logistica binaria. Resultados: A contribuicao percentual de lipideos totais mostrou-se adequada;1/3 das gestantes nao alcancou a recomendacao de ingestao diaria de acido alfa-linolenico. Gestantes com excesso de peso apresentam o dobro de chances de consumo inadequado de acido alfa-linolenico. Comparadas as gestantes das classes D/E, as pertencentes a classe C tem menores chances de consumo inadequado. Conclusao: Nao ha um problema de excesso de consumo de lipideos e sim da qualidade destes, cerca de 1/3 das gestantes acompanhadas e seus conceptos estao expostos aos efeitos adversos do baixo consumo de acidos graxos de cadeia omega-3 na gestacao, indicando importante vulnerabilidade nutricional nessa populacao.
A Carbohydrate Counting Intervention for Hispanics with Type 2 Diabetes

The purpose of this study is to determine if a culturally tailored carbohydrate (CHO) counting intervention for low-income Hispanics with Type 2 Diabetes (T2DM) will increase their knowledge and skills related to CHO counting. This non-experimental, single group design assessed knowledge of CHO counting in adult Hispanics with T2DM with preand post-surveys. Recruitment and intervention delivery were in three community locations in the Providence RI area. The intervention consisted of 3-workshops, 1-hour each, conducted in Spanish. Each workshop covered information on portion sizes guides, nutrition facts label reading, CHO amounts in commonly consumed foods and CHO counting activities. The sample was described using means and standard deviations for continuous normally distributed variables, proportion for categorical variables. Paired t-tests assessed change in knowledge. Frequency analysis described the CHO counting skill score. It was hypothesized that knowledge would increase and the post skills assessment score would exceed 80% indicating the mastery of the carbohydrate counting skill activity. Data were analyzed using SPSS Version 23. A probability level of p<. 05 was utilized. Of the 42 participants that began the program, 33 finished the intervention. Average age was 62 years and 90% were female. Participants reported an average of 6.8 years since T2DM diagnosis. The average time living in the U.S. was 25 years and 52% were from Dominican Republic. Participants had a significant increase in knowledge from preto postof 2.58 points (p<.01) and achieved 100% of the CHO counting skill score at post-assessment. The program was positively evaluated at post with an average score of 4.7 out of 5 for seven evaluation questions. The study found that low-income Hispanics with T2DM increased knowledge of CHO counting and demonstrated skills in CHO counting. This program provided an educational opportunity for low-income Hispanics with T2DM.
Polymerization of Solid-State 2,2′-Bithiophene Thin Film or Doped in Cellulose Paper Using DBD Plasma and Its Applications in Paper-Based Electronics

In this work, we present a method to prepare a conductive paper hybrid based on the polymerization of bithiophene monomer directly from the solid state of 2,2-bithiophene inside a sheet of standard letter paper using atmospheric plasma since both the monomers and some plasma species, such as radicals, can penetrate into the paper. Polymerization of a 2,2-bithiophene in its solid form using plasma offers a simple and straightforward way to synthesize a conductive polymer. To understand the polymerization reaction in atmospheric plasma, the formation of polythiophene on substrates and the reaction mechanism were investigated with Fourier-transform infrared spectroscopy (FTIR) and ultraviolet-visible (UV-VIS) spectroscopy. The kinetics of the polymerization reaction was investigated using UV-vis and the rate of polymerization was found to be the second order reaction. The resulting polymer film exhibited a conductivity of 6.67 S/cm when I2 was doped in the film. The polymerization 3,3’-dibromo-2,2’-bithiophe.
Coal Mining Impacts on Baseflow Detected Using Paired Catchments

Large‐scale coal mining not only disturbs natural landscapes but also alters catchment hydrological processes. Although investigating how mining activities such as open cut and/or underground mining change catchment baseflow is critical for understanding mining‐related hydrological mechanisms and for helping water resource management, published data on these changes have not been well documented. This study uses data‐driven approaches to examine how baseflow changes in four sets of paired catchments in the Hunter River Basin in Australia, which is one of the most intensive mining regions across the globe. The difference of cumulative anomaly percentage and double mass curves are used to detect the changes in baseflow and to identify the potential mining impacts. Our results show that underground mining has led to a decline in baseflow, while open cut mining has tended to increase baseflow, and significantly changed the baseflow trend for catchments where underground and open cut mining coexist. The mining impact signal, however, is on the top of regional climate change impacts that dominate baseflow annual variability. The data‐driven investigation cannot separate impacts due to multiple and overlapping disturbances of mining activities but provides insight and guidance for hydrological modeling to simulate mining impacts on hydrological regimes.
Application of Geographical Information Systems (GIS) and Analytical Hierarchy Process (AHP) in the Selection of A Suitable Sanitary Landfill Site for Solid Waste Disposal And

Shortage of land for waste disposal and inappropriate dump sites is the biggest problems in the Niger Delta Area of Nigeria, Warri in particular. This problem has its negative impact on human and environment owing to the menace often caused by indiscriminate dumping of solid waste. The swamping nature of the soil and the irregular topographic nature of the land hinder the flow of accumulated water formed by rains. This makes runoff during the rainy season almost impossible leading to flood in most cases. To select an appropriate site for landfill, there is need to consider different alternative areas using numerous criteria’s before making decision. In this study, geographical information systems (GIS) and analytical hierarchy process (AHP) were employed to analyze selected criteria’s that can influence the selection of a suitable site for sanitary landfill application in Warri, Delta State, Nigeria. The selected criterions include; flood extent, stream, rivers, swampy areas, ground water, built-up areas, roads, slopes, airport, palaces and point of interests (POIs). Features of interest such as roads, built-up areas, swampy areas, rivers and streams in the SPOT 5 satellite imagery were converted to vector format by digitizing in order to create a geographic database dataset. Weighted Overlay Linear Combination for map superimposition was adopted while constraints and factors were employed as the criteria for decision-making process. Suitability rating value of 1 to 5 meaning; not suitable, least suitable, moderately suitable, highly suitable and mostly suitable was use as the final index for land suitability. Results of the weighted overlay revealed three potential sites within the study area and they include; site 1, site 2, and site 3 with 3.334, 5.418 and 47/582 hectares of land suitable for sanitary landfill applications. Keyword: Sanitary landfill, weighted overlay, Suitability rating, geographical information systems (GIS), analytical hierarchy process (AHP) DOI : 10.7176/JNSR/10-2-02 Publication date: January 31 st 2020
06.07 Disease-inducible interleukin-10 gene therapy suppresses innate cytokine response in the 3d micromass model of the synovial membrane

Background No disease-modifying drugs are available for osteoarthritis (OA). Although the aetiology is still unknown, inflammation is indicated to be involved in the disease pathogenesis in many patients. Gene therapy can enable transduced joint cells to express an anti-inflammatory biological drug with long-lasting bioavailability. In addition, off-target effects can be further reduced by regulating the expression using a disease-responsive promoter that is only active during disease flares. Clinical studies in chronic diseases with anti-inflammatory recombinant Interleukin-10 (IL-10) are impeded by its short half-life. Disease-inducible gene therapy might therefore be the ideal system to provide IL-10 in an OA joint in a regulated fashion. The objective of this study was to test the feasibility of this approach in a human in-vitro model of the synovial membrane. Methods Cell suspensions of digested joint biopsies were mixed with Matrigel to form micromasses, in which the cells migrate to the surface. The micromasses were transduced with a lentiviral vector containing the IL-10 gene under control of the inflammation-sensitive CXCL10 promoter (CXCL10p-IL10) or the constitutive active PGK promoter (PGK-IL10). Subsequently, micromasses were stimulated with inflammatory triggers Tumour Necrosis Factor-alpha (TNFα) and lipopolysaccharide (LPS). Gene expression effects were determined by qPCR and the production of cytokines by the synovial micromasses was measured by multiplex ELISA. Results In 1 week cultured micromasses, migrated cells formed a lining containing both synovial fibroblasts and macrophages similar to that seen in the synovium. This lining could be efficiently targeted by lentiviruses. After stimulation with LPS and TNFα, the production of CXCL10-controlled IL-10 expression increased by 9.7-fold and 7.2-fold respectively. The IL-10 production after transduction with PGK-IL10 was not influenced by proinflammatory stimulation. The induced levels of IL-10 were high enough to significantly reduce the production of IL-1β and IL-6 by the micromasses. The anti-inflammatory effect of CXCL10-controlled IL-10 might be mediated by SOCS3. Recombinant IL-10 increased SOCS3 expression by 3.0-fold 2 hour after stimulation. Conclusions This study on primary human synovial micromasses suggest that the CXCL10p-IL-10 gene therapeutic approach to suppress the innate cytokine response in the osteoarthritic joint might be a feasible approach for local treatment of OA.
Imbalance: Mental Health in Higher Education

mbalance” is a short film and project created in Social Change Digital Production class (FILM 362) at Humboldt State University (HSU) by myself (a sociology master’s student) and fellow students Joseph Baiza, Kira Hudson, Heather Hulbert, and Andrew Weisz (film majors). The intention of the project was to heighten awareness of mental health issues among university students, especially students of HSU, stemming from the desire to break stereotypes about those who struggle with mental health and reduce stigma. The project later morphed to include the accessibility of mental health services on the HSU campus during a conversation where multiple members of the group shared how they had unsuccessfully sought services from the mental health center CAPS (Counseling and Psychological Services), either being regretfully turned away or having to wait weeks for an appointment due to the center being overimpacted. From my personal experience and observation of recent literature of diversity in higher education, I found discussion and inclusion of mental health to be scarce. Inclusion of mental health beyond mentions of depression and anxiety in discussions of diversity in higher education were even rarer. Diversity in education is intersectional and mental health is a significant social identity impacting the experiences of students in higher education. According to a survey by the American College Health Association’s (ACHA 2008) National College Health Assessment from spring 2007, stress was the number one factor impacting academic performance. In fact, five of the top six factors found impacting academic performance were psychological. The majority of mental health disorders are onset before the age of 24, around the age of many students in higher education (Kessler et al. 2007). In fact, Eisenberg et al. found that 15.6 percent of undergraduates and 13 percent of graduate students had depressive or anxiety disorder in the United States (2007). However, these percentages may be underestimates as 28.4 percent of students in the National College Health Assessment 2010 survey, diagnosed or not, reported feeling so depressed they had difficulty functioning (Castello and Schwartz 2013). In fact, according to the spring 2016 American College Health Association-National College Health Assessment survey (ACHANCHA), within a year prior to the survey, 17 percent of college students were diagnosed with or treated for anxiety and 13.9 percent were diagnosed with or treated for depression, an increase from the Spring 2011 ACHA-NCHA survey of 11.6 percent for anxiety and 10.7 percent for depression (Davidson 2016). Studies such as Byrd and McKinney (2012) have found that identity stressors can lead to depression and anxiety among students in higher education. Such identity stressors are often experienced by minority populations and include: racially tense campus climate or being singled out for one’s sexual orientation. However, it should be noted that minority racial and ethnic populations were more likely to experience poor mental health such as loneliness and/or depression whether they were of minority “I
Final Results of ECOG1100: A phase I/II study of combined blockade of the ErbB receptor network in patients with HER2- overexpressing metastatic breast cancer (MBC)

1033 Background: Activation of EGF receptor has been associated with resistance to trastuzumab in breast cancer cell lines. EGFR tyrosine kinase inhibitors inhibit HER2 phosphorylation and synergize with trastuzumab in HER2+ cell lines that co-express EGFR. Methods: Pts with MBC and HER2 overexpression by immunohistochemistry (3+) and/or HER2 gene-amplification by FISH, 0–2 prior chemotherapy regimens for met disease, LVEF 50%, and no prior trastuzumab were treated with trastuzumab 2 mg/kg/wk and gefitinib 250- 500 mg/day until disease progression, unacceptable toxicity or withdrawal of consent. The phase I portion of the trial used a 3+3 design to determine MTD. In the phase II portion of the trial, patients were stratified based upon prior chemotherapy exposure (Group 1= no prior exposure to chemotherapy, Group 2= prior exposure to 1–2 chemotherapy regimens). Response measured using RECIST criteria. The primary endpoint was to increase proportion progression free from 50 to 65% at 6 months in Group 1 an.