Miracle-dz/UniFAR-FTUs huggingface dataset:
An Experimental Study on Energy Saving for Dynamic Voltage and Frequency Scaling in Online Transaction Processing

As IT systems play more important roles in our society, their complexity and the amount of processed data is growing. That accelerates expansion of data centers and growth of energy consumption of servers, and the demand on energy-saving is becoming higher. Energy saving for database systems, which play a central role of data processing, is the key challenge in energy saving for data centers. Energy saving for database systems is becoming a hot research topic, but it is still largely unexplored. Especially there are few works on energy saving in on-line transaction processing(OLTP). This paper describes our research for energy saving in OLTP. First, a measuring system for power consumption and performance of real machines was constructed. Second, power consumptions of each system components were measured to analyze power consumption of OLTP application. Lastly, as an example of existing energy saving techniques, Dynamic Voltage and Frequency Scaling(DVFS) was applied to OLTP application and its efficacy was evaluated.
Androgen Receptor Antagonist versus Agonist Activities of the Fungicide Vinclozolin Relative to Hydroxyflutamide (*)

The mechanism of antiandrogenic activity of vinclozolin (3-(3,5-dichlorophenyl)-5-methyl-5-vinyloxazolidine-2,4-dione), a dicarboximide fungicide under investigation for its potential adverse effects on human male reproduction, was investigated using recombinant human androgen receptor (AR). The two primary metabolites of vinclozolin in plants and mammals are M1 (2-[[3,5-dichlorophenyl)-carbamoyl]oxy]-2-methyl-3-butenoic acid) and M2 (3′,5′-dichloro-2-hydroxy-2-methylbut-3-enanilide). Both metabolites, in a dose-dependent manner, target AR to the nucleus and inhibit androgen-induced transactivation mediated by the mouse mammary tumor virus promoter. M2 is a 50-fold more potent inhibitor than M1 and only 2-fold less than hydroxyflutamide. In the presence of dihydrotestosterone (50 nM), M2 (0.2-10 μM) inhibits androgen-induced AR binding to androgen response element DNA. In the absence of dihydrotestosterone, concentrations of 10 μM M2 or hydroxyflutamide promote AR binding to androgen response element DNA and activation of transcription. Agonist activities of M2 and hydroxyflutamide occur at 10-fold lower concentrations with the mutant AR (Thr to Ala) endogenous to LNCaP human prostate cancer cells. The results indicate that androgen antagonists can act as agonists, depending on ligand binding affinity, concentration, and the presence of competing natural ligands.
A preliminary genetic map of Zhikong scallop (Chlamys farreri Jones et Preston 1904)

Zhikong scallop (Chlamys farreri Jones et Preston 1904) is one of the most important aquaculture species in China. The development of a genetic linkage map would provide a powerful tool for the genetic improvement of this species. Amplified fragment length polymorphism (AFLP) is a PCR-based technique that has proven to be powerful in genome fingerprinting and mapping, and population analysis. Genetic maps of C. farreri were constructed using AFLP markers and a full-sib family with 60 progeny. A total of 503 segregating AFLP markers were obtained, with 472 following the Mendelian segregation ratio of 1:1 and 31 markers showing significant (PL 0.05) segregation distortion. The male map contained 166 informative AFLP markers in 23 linkage groups covering 2468 cM. The average distance between markers was 14.9 cM. The female genetic map consisted of 198 markers in 25 linkage groups spanning 3130 cM with an average inter-marker spacing of 15.8 cM. DNA polymorphisms that segregated in a 3:1 ratio as well as the AFLP markers that were heterozygous in both parents were included to construct combined linkage genetic map. Five shared linkage groups, ranging from 61.1 to 162.5 cM, were identified between the male and female maps, covering 431 cM. Amplified fragment length polymorphism markers appeared to be evenly distributed within the linkage groups. Although preliminary, these maps provide a starting point for the mapping of the functional genes and quantitative trait loci in C. farreri.
An empirical estimation of power output of a miniaturized wind turbine cluster

A miniaturized wind turbine cluster intended for educational purposes is used to build a 4×4 model wind turbine farm. This deployment is part of an exercise to model and optimize the output energy associated with the farm. An empirical approach is used to estimate the power and the power coefficient curves from data acquired in the field. An extrapolated power and power factor model is developed for further estimation of the power output of the wind turbines and the efficiency of the turbines at different wind speeds. The proposed approach is simple and requires minimal cost as opposed to other approaches based on wind tunnel measurements. Field experiments are carried out in this regard and the downwind distance and pitch angle are changed in field testing in terms of an experimental parameter study. The work emphasizes the potential of using small-scale models to understand and investigate interaction of wind turbines in a cluster.
Development of a three-phase high-voltage driving system for thin and flexible film motors

The aim of this study is to develop a compact and inexpensive driving system for a unique electrostatic film motor which is actuated by three-phase high voltages, the designed compact driving system contains a three-phase signal generator, a primary amplifier and a secondary amplifier. At first, the signal generator using direct digital synthesizer (DDS) is capable of easily generating high-frequency driving signals and rapidly accomplishing various control tasks (e.g., sampling sensor, computing control algorithms and so on). Next, the driving signals are amplified through two-stage amplifiers. The primary amplifier made from power operational amplifier circuits can amplify the driving signals to maximum around 40 Vp-p. The secondary amplifier adopts transformers to generate high voltage of over 1.8 kVp p. Finally, driving experiments have been performed and their results verify the validity of the designed driving system.
Smuggling and cross border shopping of tobacco in Europe

Governments have recently become concerned about cross border shopping and smuggling because it can decrease tax revenue. The tobacco industry predicted that, with the removal of border controls in the European Union, price differences between neighbouring countries would lead to a diversion of tobacco trade, legally and illegally, to countries with cheaper cigarettes. According to them this diversion would be through increased cross border shopping for personal consumption or through increased smuggling of cheap cigarettes from countries with low tax to countries with high tax, where cigarettes are more expensive. These arguments have been used to urge governments not to increase tax on tobacco products. The evidence suggests, however, that cross border shopping is not yet a problem in Europe and that smuggling is not of cheap cigarettes to expensive countries. Instead, more expensive "international" brands are smuggled into northern Europe and sold illegally on the streets of the cheaper countries of southern Europe.
Detection of structural changes through principal component analysis and multivariate statistical inference

This article introduces a new methodology for the detection of structural changes using a statistical data-driven modeling approach by means of a distributed piezoelectric active sensor network at different actuation phases. The three main features that characterize the proposed methodology are (a) the nature of the data used in the test since vectors of principal component analysis projections are used instead of the entire measured response of the structure or the coefficients of an AutoRegressive model, (b) the number of data used since the test is based on two random samples instead of some characteristic indicators, and (c) the samples come from a multidimensional variable and therefore a test for the plausibility of a value for a normal population mean vector is performed. The framework of multivariate statistical inference is used with the objective of the classification of structures in healthy or damaged. The novel scheme for damage detection presented in this article —based on multivariate inference over the principal component analysis projections of the raw data—is applied, validated, and tested on a small aluminum plate. The results show that the presented methodology is able to accurately detect damages, that is, for each actuation phase, a unique and reliable damage detection indicator is obtained no matter the number of sensors and/or actuators. It is worth noting that a major contribution of this article is that there exists an entire range of significance levels where the multivariate statistical inference is able to offer a correct decision although all of the univariate tests make a wrong decision.
Cyber-physical systems in manufacturing: Future trends and research priorities

In the last decades, the manufacturing ecosystem witnessed an unprecedented evolution of disruptive technologies forging new opportunities for manufacturing companies to cope the ever-growing market pressure. Moreover, the race to create value for the customers has been hindered by several issues that both small and large companies have been facing, such as shorter product life cycles, rapid time-to-market, product complexity, cost pressure, increased international competition, etc. In this scenario, ICT represent a crucial enabler for preserving competitiveness and fostering industry innovation. In particular, among these technologies, Cyber-Physical Systems (CPS) is growing an ever-high interest of industry stakeholders, researchers, practitioners and policy makers as they are considered the key technology that will transform manufacturing industry to the next generation. Indeed, CPS is a breakthrough research area for ICT in manufacturing and represents the cornerstone for achieving the EU2020 “smart everywhere” vision. At this early development phase, there is the urgent need to set the ground for future research streams, create a common understanding and consensus, define viable migration paths and support standards definition. This paper describes the identified research challenges and the future trends that will drive to the adoption of CPS in manufacturing. The main evidences on researches challenges expected for CPS in manufacturing are outlined by the authors that have been involved in the sCorPiuS project ‘European Roadmap for CyberPhysical Systems in Manufacturing’, promoted by the European Commission to define a roadmap for future CPS in manufacturing adoption research agenda.
Economic opportunities for sexed semen on commercial dairy farms

Dairy farmers and others have been discussing the use of enriched X-bearing semen (sexed semen) for many years (Seidel and Garner, 2002). Sexing bovine semen is possible because X-sperm have 3.8% more DNA than Y-sperm. This difference can be identified with a flow cytometer by staining the sperm with a fluorescent dye that binds to the DNA. The technique is reasonably accurate (10% error rate) but still very expensive and slow, which has limited widespread commercial application of sexed semen in the dairy industry.
Functional Analysis of a DNA-Shuffled Movement Protein Reveals That Microtubules Are Dispensable for the Cell-to-Cell Movement of Tobacco mosaic virus Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.002303.

Microtubules interact strongly with the viral movement protein (MP) of Tobacco mosaic virus (TMV) and are thought to transport the viral genome between plant cells. We describe a functionally enhanced DNA-shuffled movement protein (MPR3) that remained bound to the vertices of the cortical endoplasmic reticulum, showing limited affinity for microtubules. A single amino acid change was shown to confer the MPR3 phenotype. Disruption of the microtubule cytoskeleton in situ with pharmacological agents, or by silencing of the α-tubulin gene, had no significant effect on the spread of TMV vectors expressing wild-type MP (MPWT) and did not prevent the accumulation of MPWT in plasmodesmata. Thus, cell-to-cell trafficking of TMV can occur independently of microtubules. The MPR3 phenotype was reproduced when infection sites expressing MPWT were treated with a specific proteasome inhibitor, indicating that the degradation of MPR3 is impaired. We suggest that the improved viral transport functions of MPR3 arise from evasion of a host degradation pathway.
Adaptive Pseudo Dual Keeper for Wide Fan-In Dynamic Circuits

This brief presents a novel keeper technique for high-performance and high-noise-immunity wide fan-in dynamic circuits. Two major innovations are proposed, i.e., the adaptive pseudo dual keeper technique, which can either significantly reduce evaluation contention or maximize immediate noise immunity through a simple single keeper structure, and the diode-connected self-biasing circuit to minimize the static current of the adaptive pseudo dual keeper. Both these original design concepts help to achieve higher performance and lower power consumption while maintaining the high noise immunity. Several wide fan-in dynamic gates were designed using UMC 90-nm 1-V technology. Our simulation results demonstrate that using the proposed keeper technique, the 32-bit or gate and multiplexer can achieve delay reductions of at least 22% and 17.7%, respectively, for the same unity-gain direct-current noise (UGDN)-immunity requirement, as compared with conventional keeper techniques. Meanwhile, power dissipation is reduced by up to 55.3% due to the simple keeper structure and contention reduction. The simulations also show that circuits with the proposed keeper show small variations in delay and power consumption over a wide range of noise-immunity requirements, e.g., they vary by only 2.1% and 3.2% for a 32-bit multiplexer with 0.24- to 0.32-V UGDN levels.
Aromatic amino acids and modification of parkinsonism.

THE known biochemical abnormalities in Parkinson's disease consist of a decrease of melanin pigment in the substantia nigra1 , 2 and a decrease of some biogenic amines in the substantia nigra and the corpus striatum.3 These 2 defects might be interrelated, as suggested by the fact that in both melanocytes4 and sympathetic cells5 tyrosine is hydroxylated to dihydroxyphenylalanine, a common precursor in the synthesis of both melanin and catecholamines. Furthermore, both melanocytes and sympathetic cells originate from the neural crest.6 It was suggested earlier7 , 8 that the interrelations between melanogenesis and extrapyramidal disease might be of fundamental importance. It was noted that chronic .
Fabrication of low cost wafer-level micro-lens arrays with spacers using glass molds by combining a Chemical Foaming Process (CFP) and a Hot Forming Process (HFP)

This paper reports an innovative molding process for the fabrication of low cost wafer-level micro-lens array with spacers of optical applications. The concave mold for the micro-lens includes two parts: the upper glass mold and the under silicon mold. The upper glass mold was prepared by combining the Hot Forming Process (HFP) and the Chemical Foaming Process (CFP). The under silicon mold was prepared by etching. Specially designed concave structures were prepared on both parts. An anti-adhesion layer was formed on the surface of the concave mold. UV-light curable glue, the lens material, was injected into the concave mold and cured. Results show that wafer-level micro-lens arrays with spacers were successfully fabricated after de-molding the reusable mold. Samples of 6×6 micro-lens arrays with spacers, in diameter of 800μm and pitch of 2600μm, were prepared. Fabrication imperfection and design of micro-lens array was discussed.
Status of survivors after atrial redirection for transposition of the great arteries: a complete long‐term follow‐up

All 32 survivors with transposition of the great arteries, born in 1964‐83 and operated on at our institution using atrial redirection, were evaluated by cardiac catheterization, echocardiography and Holter monitoring. There were 17 Mustard patients, age 17.1 years (±3.5, 12.0‐22.0) and 15 Senning patients, age 9.4 years (±1.6, 7.2‐12.1). All but one had simple transposition. Six had caval obstruction, one had pulmonary venous obstruction, three had large atrial shunts, four had considerable pulmonary hypertension, seven had mild ventricular outflow tract obstruction, four had significant tricuspid regurgitation, 11 had systemic ventricle dysfunction (one severe), 14 had sinus node dysfunction (three symptomatic) and two had atrioventricular block (one with pacemaker). Eight Mustard patients (47%) and one Senning patient (7%) had symptomatic cardiac sequelae, and only one patient (Senning) was free from sequelae, illustrating that these patient groups will need continuing medical attention.
Multiple sensors on pulsed eddy-current detection for 3-D subsurface crack assessment

This paper proposes the use of multiple sensors in pulsed eddy-current detection for three-dimensional (3-D) subsurface flaw imaging. A normalization technique has been proposed to eliminate the characteristic variation among the Hall devices used in the probe and lift off effects. A principal component analysis-based feature extraction that provides orthogonal information for multiple sensor fusion has been introduced and investigated. Using the features of multiple projection coefficients, 3-D surface flaws can be measured and reconstructed. The experimental tests have illustrated that the proposed method has delivered more defect information than the conventional peak value and time for pulsed eddy-current sensors.
New experimental regimens for preventive therapy of tuberculosis.

Active tuberculosis is now recognized as a frequent and serious complication of infection with the human immunodeficiency virus (HIV), the causative agent of AIDS. HIV mediated alteration in host defenses against mycobacteria contribute to the magnitude and severity of this problem. HIV can affect a variety of cellular mechanisms important in the restriction of mycobacterial growth. Qualitative and quantitative defects in T lymphocyte function result from direct HIV infection of cells expressing the CD4 epitope, and can severely limit the production of macrophage activating cytokines capable of inducing an anti-mycobacterial state in cells of monocyte lineage. In addition, macrophages themselves are susceptible to HIV infection, and have been shown to be defective with respect to a variety of host defense functions. Both T4 lymphopenia and HIV infected macrophages are present in the lower respiratory tract of HIV infected individuals, a circumstance which likely underlies the unique susceptibility of HIV infected to tuberculosis.
Survival in Alzheimer's disease and vascular dementias.

All patients were initially evaluated at the Geriatric Evaluation Service Dementia Clinic at the Burke Rehabilitation Center, Cornell University Medical Center. After an initial evaluation, history and physical examination, which included various laboratory tests, the patients were evaluated by various psychometric tests and behavior rating scales (Modifed Hachinski Ischemic Score, Haycox Behavioral Score and Blessed, Tomlinson and Roth Behavior Score). The diagnostic groups were based upon the initial evaluation and follow-up data to include autopsy information, if available. Any patient with a treatable cause of dementia or other medical conditions was excluded from this stud3a
The Relationship Between Job Stress and Quality of Life for Hospital Workers by Type of Employment.

The Relationship Between and Objective: This study was conducted to evaluate the relationship between job stress and quality of life for hospital workers by type of employment. Methods: Data were obtained for 361 workers in a large hospital 172 of whom were categorized as typical workers defined by permanent employee and 189 of whom were categorized as atypical workers defined by fixed-term contraction. Job stress was assessed using the Korean Occupational Stress Scale-Short Form and the World Health Organization Quality of Life-BREF Questionnaire Results: Atypical workers had significantly higher scores for job-related stress in the domains of insufficient control, over work, job insecurity, and lack of reward in the workplace compared with typical workers, who had higher scores for stress in the domains of job demands and occupational climate. Test scores also indicated that typical workers had a significantly better quality of life than atypical workers, especially in terms of mental health, social relationships and environment. Conclusion: These findings suggested that factors contributing to job-related stress were different between typical and atypical hospital and typical workers are likely to have a better quality of life.
Performance comparison between arrays with rotating linear polarization elements and circular polarization elements

In this paper , it is shown that, for large element spacing, a rotating LP elements' array becomes 50% less aperture efficient than a CP elements' array . On the other hand, for small element spacing, the difference in aperture efficiency between the two arrays is negligibly small. Consequently, for small element spacing, the rotating LP elements' array is likely to have more overall efficiency than the CP elements' array because the latter has the additional RF loss due to polarizer circuitry. Furthermore, it is found that in the array environment the return loss bandwidth of an LP elements' array is narrower than that of a CP elements' array. In order to have a complete characterization of the two arrays, we present numerical results based on a full wave Floquet MoM analysis of slot-fed patch elements. Advantages and disadvantages of the two arrays are discussed.
Linking Corporate Social Responsibility, Tourism and Climate Change to Build Tourism Community Adaptive Capacity to Climate Change in Bali

The emerging body of literature has reported the impact of climate change on tourism destination. Although it is recognized that tourism-dependent destination communities will be heavily affected by climate change, very little research has been undertaken in developing countries. Moreover, our understanding of how CSR of tourism businesses plays a role in building community adaptive capacity to climate change remains limited. To address these fundamental gaps, this thesis --- i. Combines theoretical advances from climate change, CSR and adaptive capacity research to develop a conceptual framework; and --- ii. Uses this framework to guide a case study to allow a better understanding of how CSR practices can enhance tourism community adaptive capacity to climate change.
Cluster Policy: A Strategy for Boosting Competitiveness and Wasting Money?

In this paper we take a critical view of cluster policy from a theoretical perspective. We argue that the concept of clusters is correctly based on agglomeration economies which imply externalities and complex non-linear dynamics of the respective economic system. This has fundamental implications for the dynamics of the system. Cluster policy can work because of agglomeration economies. However, agglomeration economies also imply major dilemmas for cluster policy which are in the areas of sectoral and temporal targeting and are discussed in this paper