Miracle-dz/UniFAR-FTUs huggingface dataset:
The stop null mice model for schizophrenia displays [corrected] cognitive and social deficits partly alleviated by neuroleptics.

Recently, evidence has been accumulated that schizophrenia can arise from primary synaptic defects involving structural proteins and especially microtubule associated protein. Previous experiments have demonstrated that STOP gene deletion in mice leads to a phenotype mimicking some aspects of positive symptoms classically observed in schizophrenic patients. Here we have assessed social and cognitive functions in STOP null mice. Compared to wild-type mice, STOP null mice exhibited deficit in the non-aggressive component of social recognition, in short term working memory and in social and spatial learning, which, as in human schizophrenia, were poorly sensitive to a long term treatment with typical neuroleptics. Since, social and cognitive dysfunction have consistently been considered as central features of schizophrenia, we proposed that STOP null mice may provide a useful model to understand the neurobiological correlates of social and cognitive defects in schizophrenia and to develop treatments that better target these symptoms. measuring conspecific interactions in home-cage. null ), as a proof of concept, we tested the effect of a long-term NL treatment on the behavior of mice in the conspecific recognition 2005 test and in the spatial learning olfactory guided test. The spatial and social learning abilities were compared in drug free and long term NL-treated wild-type (WT) and STOP null mice.
Architectural Integration for Wireless Communication Security in terms of integrity for Advanced Metering Infrastructure-Survey Paper

— At present, cyber-security has become very significant problem. The universal security integration give number of cyber-security standards. These standards deliver different digital security methods which are established to escape cyber-security attacks. These standards suggest general outlines and accurate techniques for implementing cyber-security. For architectural integration the cyber-security standards play vital role. In this paper, authors are trying to improve wireless communication security for Advanced metering infrastructure by providing reliable architectural integration in terms of integrity. AMI is key part of the Smart Grid (SG). From the collected work it is clear that, AMI provides efficiency, reliability, scalability and privacy but due to security problem it lowers the performance. Wireless communication security of AMI to be determined by considering four parameters that is confidentiality (C), integrity (I), availability (A) and accountability (Ac) or non-repudiation. The number of researchers has done work on wireless communication security for AMI but stagnant there is enormous problem of security. Because of still no one researcher has considered four security parameters. By considering these four parameters we can see drastic change in wireless security for AMI. Improvement in these parameters, AMI will be more advanced. But in this paper we are going to focus on wireless security for AMI in terms of Integrity only. AMI totally depends on wireless communication network. And now days AMI suffers from various cyber-attacks on wireless communication network. A security framework and architectural integration are the things necessary for confident communication of data and control messages. Existing security algorithms are not suitable for smart grid data communication because of their large execution time, more cost and the requirement of more memory. This paper tries to provide security algorithm in terms of integrity with less time and cost. After surveying the existing security solutions in this area, we propose for wireless communication security WiMAX technology (Worldwide Interoperability or Microwave Access Smart architectural integration is very essential for AMI. Infrastructure of AMI consists of basic steps like power generation, substation and distribution. Different attacker attacks on AMI infrastructure. By improving architecture we can make AMI more secure.
Data analytics : an exploration of quality control to determine students' academic performance

Quality control and improvement is a crucial process development of any institution that craves growth. One part of the SPC approach is to aid the constant improvement of performance by further reducing unexplained variability. Another aspect of Statistical Process Control (SPC) is that planned and unplanned changes signaled as fast as considering the natural process variability. This paper aimed to determine whether students' performance is significantly distributed according to academic patterns using the quality control procedure. This study found that one of the notable Nigerian Private University student academic performances drawn from three engineering departments based on the mean chart is in control and out of control, indicating excellent, intermediate, and lower results. The study also shows upper, average, and lower results with a close margin. This insight is an interdepartmental issue. The school managers need to formulate a holistic policy that will improve the existing academic performance to move the outlier students from worst to better and from better to best.
Expanding WordNet with Gloss and Polysemy Links for Evocation Strength Recognition

Expanding WordNet with Gloss and Polysemy Links for Evocation Strength RecognitionEvocation – a phenomenon of sense associations going beyond standard (lexico)-semantic relations – is difficult to recognise for natural language processing systems. Machine learning models give predictions which are only moderately correlated with the evocation strength. It is believed that ordinary graph measures are not as good at this task as methods based on vector representations. The paper proposes a new method of enriching the WordNet structure with weighted polysemy and gloss links, and proves that Dijkstra’s algorithm performs equally as well as other more sophisticated measures when set together with such expanded structures. Rozszerzenie WordNetu o glosy i relacje polisemiczne na potrzeby rozpoznawania siły ewokacjiEwokacja – zjawisko skojarzeń zmysłowych wykraczających poza standardowe (leksykalne) relacje semantyczne – jest trudne do rozpoznania dla systemów przetwarzania języka naturalnego. Modele uczenia maszynowego dają prognozy tylko umiarkowanie skorelowane z siłą ewokacji. Uważa się, że zwykłe miary grafowe nie są tak dobre w tym zadaniu, jak metody oparte na reprezentacjach wektorowych. Proponujemy nową metodę wzbogacania struktury WordNet o polisemie ważone i linki połysku i udowadniamy, że algorytm Dijkstry zestawiony z tak rozbudowanymi strukturami działa a także inne, bardziej wyrafinowane środki.
Molecular Linking of HIPEC (Hyperthermic Intraperitoneal Chemotherapy) and Tregs (Regulatory T- cells) in Advanced Epithelial Ovarian Cancer - A Review

The mainstay in the management of advanced epithelial ovarian cancer is platinum-based chemotherapy and complete cytoreductive surgery. Despite this, about two-thirds of patients have disease recurrence mostly within the peritoneal cavity. HIPEC (Hyperthermic Intraperitoneal Chemotherapy) is a modality that delivers cell-cycle non-specific chemotherapeutic agents along with heat 41°C to 43°C into the peritoneal cavity. HIPEC is done intra-operatively after achieving complete cytoreduction (which means after removal of all the tumor deposits more than 2.5 mm). Ovarian cancer is associated with the frequent finding of tumor-infiltrating lymphocytes in their tissue microenvironment. Especially studies have shown that ovarian cancer evades immune surveillance by higher expression of FOXP3 T cells. HIPEC has been used in the treatment of primary and recurrent tumors. In this review, we discuss how the significance of HIPEC on genetics and immunology of these patients with cancer have provided unique insights into the molecular and cellular basis of Treg cells. Studies of HIPEC and its association with Tregs cells should make it possible to increase the paucity of immuno- therapeutic modalities of most human cancer at an unprecedented level of molecular and cellular precision. The predictive, preventive, and therapeutic implications of these studies of HIPEC in relation to immunity in EOC may extend to patients with other peritoneal carcinomatosis.
Does Board Composition Matter? The Relationship Between Board Characteristics and Financial Performance: Evidence From Chinese Listed Agricultural Companies

The paper aims to make new insight to some of the contradicting findings in prior studies of the board structure–firm performance relationship and to assess this connection in the specific context of Chinese listed agricultural companies practice. The study investigates the data of Chinese agricultural listed companies from 2008 to 2017, using multiple regression authors examine the relationship between board characteristic and financial performance. Conducted by authors empirical analysis shows that CEO duality and board size are significantly positively correlated with financial performance (proxies - ROA, ROE, and EPS). Although, contrary to the findings made in Western institutional settings the paper’s results testify that board independence has no significant impact on financial performance in China. The study’s findings enrich the understanding of linkage “board structure–firm performance”, especially in China – institutional settings that have proved to differ in many ways from other jurisdictions. Additionally, the paper provides an in-depth synthesis of research into this linkage to the date.
Fetomaternal outcomes in conservative management of preterm premature rupture of membrane

Background: The management of PPROM remains controversial. Aim of this study was to determine the fetomaternal outcome in conservative management of PPROM. Methods: A prospective observational study was done on a total of 110 pregnant women between 24 and 36 weeks 6 days gestation with PPROM visiting Geetanjali medical college and hospital from February 2019 to July 2020. All the patients were subjected to detailed history and examination and followed till their delivery. Results: The incidence of PPROM in our study was 4.94%. The mean latency period from membrane rupture to delivery decreased from 12.1±14 days at >28 weeks, 5.3±7.7 days at 28-31 weeks 6 days to 1.1±1.2 days at 32 to 36 weeks 6 days. The most common indication of LSCS was fetal distress (26.31%). E. coli was the most common organism (36.36%) isolated and it was significantly associated with gestational age at PPROM (p value <0.040405). The maternal morbidity was 24.53% and was closely associated with the gestational age at PPROM (p value <0.001). The perinatal morbidity was 44.20% and perinatal mortality was 13.04% which was mainly due to RDS (33.34%). Conclusions: Management of PPROM involves complete evaluation of risks and benefits of conservative management. The treatment should be directed toward conserving the pregnancy with prophylactic use of antibiotics and corticosteroids thereby reducing fetomaternal morbidity and mortality. However, termination of pregnancy should be considered at the earliest suspicion of chorioamnionitis, septicaemia.
Skin graft of contralateral aesthetic unit for reconstruction of the upper eyelid: case report and literature review

Eyelids represent a complex structure; its principal function is to provide physical and immunological barrier. The complexity of this structure lies in the blinking and in the range of movement they carry out respecting the integrity of the cornea. The objective of this study is to provide a surgical alternative with minimal morbidity for the reconstruction of the upper eyelid, as well as to present the available tools for the treatment of this complex area of the facial anatomy. We present the case of a female patient of 62 years, with 50% of necrosis on the surface of the upper eyelid and infection data, surgical management was initiated with debridement, systemic antibiotic therapy and negative pressure system device, once the infectious process was resolved and according to the principles of reconstruction by aesthetic subunits, it was decided to reconstruct 100% of the subunit affected by a skin graft of total thickness of the contralateral eyelid through a blepharoplasty with good aesthetic-functional results. The reconstruction of the eyelids should be managed by a plastic surgeon, taking into account the principles of the aesthetic subunits, optimally the donor tissue should have similarity with the tissue to be reconstructed, with respect to the size, color and flexibility, to obtain an adequate aesthetic and functional result.
Microbial modulating effect of xylanase enzyme supplemented rice husk on the gastrointestinal tract of broiler chickens

The development of antibiotics-resistance pathogens in poultry which poses threat to human health has necessitated the search for alternative to antibiotic growth promoters (AGPs) to improve gut microflora in poultry diets. One of the alternatives to AGPs is probiotics which are beneficial organisms. The prebiotic potentials of enzyme supplemented high fibre feedstuffs (HFFs) are not known. This study was conducted to assess the prebiotics potential of xylanase enzyme supplemented rice husk (RH) on broiler chickens (in-vivo). The study showed that replacement of maize with RH irrespective of levels supplemented with 100ppm xylanase enzyme caused a reduction in feed intake and an increase in weight gain and better FCR. It was observed that birds fed diet with 10% RH supplemented with xylanase enzyme out-performed birds fed diets with 20 or 30% RH supplemented with xylanase enzyme and closer to the birds fed the control diet which was with better FCR. Enzyme supplementation of RH helped in increasing and improving protein, ether extract and fibre digestibilities. The identification of microbes (Fungi and Bacteria) showed that dietary levels of RH (10, 20 or 30% inclusion) with supplementation of enzyme xylanase enhanced the growth of beneficial microbes which resulted in inhibition or elimination of the opportunistic/pathogenic microbes. The result of the cost benefit analysis also showed that 10% inclusion level of RH supplemented with xylanase enzyme gave the best result of a beneficiary reduction in the cost of production with the best improved broiler performance. The use of enzymes is therefore recommended when RH are required as prebiotic source in the gut of broilers.
Stylistics analysis of "The charge of the light brigade" by Alfred lord Tennyson

Stylistics relative to interpreting literature shows how an author created the literary piece. It identifies the ways a writer chooses the language in weaving the text. Further, it works on the premise that without language, there can be no literature. The stylistics analysis of “The Charge of the Light Brigade” provided a deeper understanding of the specific messages of the poem and broader knowledge of the language in general. It identified the usage patterns used by Alfred Lord Tennyson in writing the poem which resulted to a more competent appreciation of the literary work. The analysis revealed how cleverly he weaved each line on the poem that changing the arrangement would ruin the beauty of the poem.
Parametric or Non-parametric? Understanding the Inherent Trade-offs between Forms of Object Representation

– The need for efficient computing in construction modelling and analysis workflows often requires making tradeoffs between the inherent advantages and disadvantages of different datatypes being generated and managed. This is notably observed in geometry reconstruction (e.g., scan-to-BIM, reverse engineering, etc.), where a tradeoff often occurs between computational efficiency and the choice between increased semantic enrichment or increased representational accuracy (often both cannot be achieved simultaneously). This dichotomy can be generalized as a choice or tradeoff between parametric and non-parametric object representation forms. This paper presents a simple conceptual model for characterizing the datatypes used for representing and defining construction geometry to understand key tradeoffs that exist. First, we survey existing literature across multiple domains to identify and distill key attributes used in characterization according to the terms parametric and non-parametric. Then, we develop and illustrate a conceptual model using an analogy to mathematical expressions vs. discrete digital approximations employed in computer vision (e.g., Gaussian kernel, Hough Transform, and Scale Invariant Feature Transform (SIFT) algorithm). Finally, we outline future research opportunities for improving the state of object representation.
Tri-PLS for compositional data

Gallo M.a∗, Trendafilov N.b , Todorov V.c and Martı́n-Fernández J.A. d aDepartment of Human and Social Sciences, University of Naples-L’Orientale, P.zza S.Giovanni 30, Naples (It-80134), Italy bDepartment of Mathematics and Statistics, The Open University, Walton Hall, Milton Keynes MK7 6AA, UK cUnited Nations Industrial Development Organization, Wagramerstr 5 P.O. Box 300 A-1400, Vienna, Austria d Departament IMAE, Universitat de Girona, Campus Montilivi, Edif. P-IV, Girona (E-17071), Kingdom of Spain
Autoimunitní tyreoiditida – vybrané etiopatogenetické mechanizmy

Souhrn: Autoimunitní tyreoiditida se jako orgánově specifické autoimunitní onemocnění vyskytuje nejen v podobě samostatného poškození štítné žlázy, ale i ve vazbě na řadu autoimunitních endokrinopatií. Byla sledována genetická predispozice v oblasti HLA antigenů u takto diagnostikované autoimunitní tyroiditidy a ukázalo se, že genetická predispozice u samostatné autoimunitní tyroiditidy je odlišná ve srovnání s výskytem vázající se na endokrinní polyglandularitu. U vybraných skupin autoimunitní tyroditidy byl sledován i vliv vnějších faktorů na rozvoj autoimunitního procesu, a to jak vliv těžkých kovů, tak vliv infekčního agens – Helicobacter pylori. I tyto vlivy měly odlišný charakter aktivace autoimunitní tyroiditidy v závislosti na samostatném projevu či ve vazbě na autoimunitní polyglandulární syndrom II. typu, či na skupinu polyglandulární aktivace autoimunity. Závěrem této studie vzniká předpoklad, že autoimunitní tyroiditida je souborem klinických syndromů v závislosti na aktivaci autoimunitního procesu a nejedná se o striktně geneticky a epigeneticky charakterizovanou nozologickou jednotku.
Ni(II) and V(IV) Schiff base complexes derived from 2,2′-dimethylpropandiamine: the crystal structure, electrochemical properties and catalytic activities in oxidation of sulfides

Abstract Tetradentate Schiff base (H2L) derived from 2,2′-dimethylpropandiamine and its nickel(II) and oxo-vanadium(IV) complexes (NiL, VOL) have been prepared and characterized. The crystal structure of NiL has been determined. The reported structure contains two molecules of the complex revealing slightly different conformation and the coordination sphere around nickel is distorted square planar. The electrochemical properties of the Ni and oxo-vanadium Schiff base complexes were investigated in CH3CN by cyclic voltammetry. The catalytic activities of the complexes were studied in the oxidation of sulfides in ethanol. Under the optimized reaction conditions, in the presence of NiL, 89% and VOL, 100% conversion of methyl phenyl sulfide with 100% selectivity for sulfoxide were obtained.
Factory Automation and Learning Capability in the Knowledge Transfer Process of Multi-National Corporations: A Case Study of Japanese Healthcare Company

In a volatile global environment, it is critical to respond to unpredictable variables in the global market. Multi-national corporations (MNCs) operating across national boundaries face complex risks and a high level of uncertainties. Therefore, MNCs need to sense changing market dynamics and prepare diverse responsive options with future scenario planning. In terms of global management with subsidiaries, MNCs that target the global market need to implement a balance of global business integration and local adaptation. Recent new technologies are one critical factor that contributes to this balance. The introduction of new automation machines to the production line is also an external force of change, requiring line workers to acquire new knowledge as well. Understandably, many Japanese domestic firms have enthusiastically introduced machines and robots to automate their factories. In response to this automation fever, we investigate under what conditions automation might be a barrier to effective
Awareness of Diabetic Eye Diseases in Diabetic Patients

The study aims to assess the awareness of diabetic eye disease among diabetic patients. Diabetesmellitus is a rapidly growing global concern that may cause several complications. The ophthalmic complications that diabetic patients are prone to are diabetic retinopathy, cataract, and glaucoma. One of themost commonmicrovascular complications of diabetes is diabetic retinopathy. The study is a community-based cross-sectional descriptive study involving 100 diabetic patients who visited a tertiary care hospital, Saveetha Medical College who gave consent for the study. Ethical clearance was obtained from the Institutional Review Board (IRB). The 100 study participants illed up a structured questionnaire with 26 questions that were validated by two experts in the ield. The age, gender, educational status, occupation, duration of diabetes, undergoing treatment, associated risk factors, awareness regarding diabetes caused ophthalmic complications, their knowledge on how important regular eye check-ups are for the diabetic patients, andwhether they are aware that it could cause blindness. Thequestionnaire also assessed their practice patterns for regular eye check-ups. The results were presented in the form of text, pie charts, tables, and igures. 86% of the study participants knew that diabetes could cause eye diseases. 8% knew that diabetes could cause cataract. 65% knew that diabetes could cause glaucoma.70%knew that diabetes could cause diabetic retinopathy. These results were compared to the results of similar researchpapers. Though there is awareness amongst themajority of the study participants, the practice pattern shows that 54% of the study participant do not go for regular eye check-ups. More community awareness is required for better ef iciency to prevent treatable blindness in India.
Analyzing and Comparing Data Forwarding Components in POX Software Defined Networking Controller

Software Defined Network (SDN) decouples networks control plane and data plane, make the controller gain the global network topology view which can be utilized by the controller’s forwarding applications to forwards the packets between hosts with the helping of openflow protocol. The POX controller and Mininet tool has been used to simulate the underlying SDN infrastructure. This paper analyze a different data forwarding components currently supported by the POX controller, where three components are compared, hub, l2_learning, and l2_multi, by measures the Round Trip Time (RTT) and CPU usage.