Miracle-dz/UniFAR-FTUs huggingface dataset:
Pulmonary manifestations of chronic liver disease: a comprehensive review

Hepatopulmonary syndrome (HPS) and porto-pulmonary hypertension (PoPH) represent relatively common pulmonary vascular complications of advanced liver disease. Despite distinct differences in their pathogenetic background, both clinical states are characterized by impaired arterial oxygenation and limited functional status, and are associated with increased pre-transplantation mortality. Accumulation of ascitic fluid in the pleural cavity, known as hepatic hydrothorax (HH), is another frequent manifestation of decompensated cirrhosis, which may cause severe respiratory dysfunction, depending on the volume of the effusion, the rapidity of its development and its resistance to therapeutic measures. Orthotopic liver transplantation constitutes the only effective treatment able to resolve the pulmonary complications of liver disease. A prioritization policy for liver transplantation has evolved over the past years regarding advanced stages of HPS, yielding favorable outcomes regarding post-transplantation survival and HPS resolution. In contrast, severe PoPH is associated with poor post-transplantation survival. Hence, liver transplantation is recommended only for patients with PoPH and an acceptable reduction in pulmonary pressure values, after receiving PoPH-targeted vasodilating therapy. This review focuses on basic pathogenetic and diagnostic principles and discusses the current therapeutic approaches regarding HPS, PoPH, and HH.
Exercise-dependent changes in ventricular–arterial coupling and aortopulmonary collateral flow in Fontan patients: a real-time CMR study

Abstract Aims Inefficient ventricular–arterial (V–A) coupling has been described in Fontan patients and may result in adverse haemodynamics. A varying amount of aortopulmonary collateral (APC) flow is also frequently present that increases volume load of the single ventricle. The aim of the study was to assess changes in V–A coupling and APC flow during exercise CMR. Methods and results Eighteen Fontan patients (age 24 ± 3 years) and 14 controls (age 23 ± 4 years) underwent exercise CMR using a cycle ergometer. Ventricular volumetry and flow measurements in the ascending aorta (AAO), inferior (IVC), and superior (SVC) vena cava were assessed using real-time sequences during stepwise increases in work load. Measures of systemic arterial elastance Ea, ventricular elastance Ees, and V–A coupling (Ea/Ees) were assessed. APC flow was quantified as AAO − (SVC + IVC). Ea remained unchanged during all levels of exercise in both groups (P = 0.39 and P = 0.11). Ees increased in both groups (P = 0.001 and P < 0.001) with exercise but was lower in the Fontan group (P = 0.04). V–A coupling was impaired in Fontan patients at baseline (P = 0.04). Despite improvement during exercise (P = 0.002) V–A coupling remained impaired compared with controls (P = 0.001). Absolute APC flow in Fontan patients did not change during exercise even at maximum work load (P = 0.98). Conclusions Inefficient V–A coupling was already present at rest in Fontan patients and aggravated during exercise due to a limited increase in ventricular contractility which demonstrates the importance of a limited functional reserve of the single ventricle. APC flow remained unchanged suggesting no further increase in volume load during exercise.
Obesity & its homoeopathic approach

Obesity is a condition where a person has accumulated so much body fat it might have a negative effect on their health. If a person body weight is at least 20% higher than it should be he/she is considered obese. Excess of weight increases the mortality due to the complications arising out of it. Obesity also acts like a precursor of many dangerous systemic illnesses like Diabetes Mellitus, hypertension and cardiovascular diseases, etc. and thus knowing its cause and treatment is of prime importance. 5% to 10% weight loss can significantly improve health, quality of life, and economic burden of an individual and a country as a whole. Homoeopathic medicines don’t have any side effect on the body unlike conventional treatments. Homoeopathic medicines are extremely effective in reducing weight by speeding up the metabolic rate. This article emphasis on incidence, etiology, pathogenesis, clinical features and management of Obesity with discussion on homeopathic medicines indicated in this clinical condition.
Vegetative propagation of Eucalyptus using tissue culture and its application to forest improvement in Western Australia

Conventional vegetative propagation from mature eucalypts is not possible for most species, but micropropagation has been successfully used for several species (1, 2). Jarrah (Eucalyptus marginata Sm.), is an important forest species limited to Western Australia. There are some 1,400,000 ha. in state forest reserves, but 280,000 ha. of these have already been affected by dieback and the increase in a year may be up to 16,000 ha. A root pathogen, Phytophthora cinnamomi Rands appears responsible for the disease (3). Another serious pest is the leaf miner (Perthida glyphopa Common), a moth whose larvae damage leaf tissue (4). Healthy trees are occasionally found in dieback sites, and trees apparently resistant to leaf miner occur in the forest. We wish to clone these trees and test them for genotypically controlled resistance.
Carbon Balance under Organic Amendments in the Wheat-Maize Cropping Systems of Sloppy Upland Soil

With an increasing interest in closing the nutrient loop in agroecosystems, organic amendments are highly recommended as a reliable resource for soil nutrient recycling. However, from a carbon sequestration perspective, not much has been reported on the contribution of different organic amendments to soil organic carbon (SOC), crop carbon (C) uptake, and soil carbon dioxide (CO2) emissions in wheat-maize cropping systems of sloppy upland soil. To fill the knowledge gap, a two-year lysimeter-field plots experiment was conducted in a sloppy upland purplish soil under wheat-maize cropping systems. The experiments were arranged in a complete random block design with five treatment plots, namely; fresh pig slurry as organic manure (OM), crop residues (CR), conventional mineral fertilizers (NPK) as the control, organic manure plus mineral fertilizers (OMNPK), and crop residues plus mineral fertilizers (CRNPK). Our results showed the leaf photosynthesis rate was not significantly increased by organic amendment application treatments compared to NPK treatment, and was within a range of 4.8 to 45.3 µmol m−2 s−1 for the wheat season and −20.1 to 40.4 µmol m−2 s−1 for the maize season across the five treatments and the measured growth stages. The soil CO2 emissions for the maize season (in the range of 203 to 362 g C m−2) were higher than for the wheat season (in the range of 118 to 252 g C m−2) on average across the different experimental treatments over the two-year experiment. The organic amendment application increased annual cumulative CO2 emissions from 30% to 51% compared to NPK treatment. Over the two years, the average crop C uptake ranged from 174 to 378 g C m−2 and from 287 to 488 g C m−2 for the wheat and maize seasons, respectively, and the organic amendment application increased the crop C uptake by 4% to 23% compared to NPK treatment. In the organic amendment treatments, the C balance ranged from −160 to 460 g C m−2 and from −301 to 334 g C m−2 for the wheat and the maize seasons, respectively, which were greater than those in the NPK treatment. Overall, the present study results suggest incorporation of organic amendments could be an effective strategy for increasing C sequestration and sustaining crop productivity in sloppy upland soil.
Role of Transrectal Ultrasound Elastography in the Diagnosis of Prostate Carcinoma

Background: The purpose of this study was to evaluate the diagnostic value of transrectal real- time strain elastography (RTE) in identifying prostatic carcinoma (PCa). Methods: 60 patients suspected of having PCa based on abnormal digital rectal examination and raised prostate specific antigen levels underwent transrectal ultrasound (TRUS), color Doppler (CD) and RTE. Elastograms were scored on a five point scale based on distribution of strain in relation to hypoechoic area on TRUS. Twelve core systematic biopsy as well as targeted biopsy was performed from suspicious areas on TRUS and RTE. Diagnostic performance of sonoelastography was evaluated using histopathology as reference standard. Results: Histopathology revealed cancer in 28 out of 60 patients (47%) studied. Gleason score ranged from 6 to 9. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of TRUS in detecting prostate cancer were 78.57%, 81.25%, 78.57%, and 81.25%, respectively. On CD evaluation 87.5% (n = 28) of benign lesions showed symmetric, radial flow compared to 14.3% (n = 4) of malignant lesions (P < 0.0001). The sensitivity and specificity of RTE was 89.29% and 56.25% with PPV and NPV being 58.13% and 82.35%, respectively. Higher elastography score was found to be significantly associated with malignant histopathology (P = 0.004). Cancer detection rate with RTE was greater for tumors with higher Gleason score. Conclusion: RTE was found to have better sensitivity than TRUS as well as combination of TRUS and CD. Although less specific, RTE can be an effective adjuvant tool to TRUS for guidance of biopsy and improve detection rate of PCa.
A New Efficient Step-Up Boost Converter with CLD Cell for Electric Vehicle and New Energy Systems

An increase in demand for renewable energy resources, energy storage technologies, and electric vehicles requires high-power level DC-DC converters. The DC-DC converter that is suitable for high-power conversion applications (i.e., resonant, full-bridge or the dual-active bridge) requires magnetic transformer coupling between input and output stage. However, transformer design in these converters remains a challenging problem, with several non-linear scaling issues that need to be simultaneously optimized to reduce losses and maintain acceptable performance. In this paper, a new transformer-less high step-up boost converter with a charge pump capacitorand capacitor-inductor-diode CLD cell is proposed using dynamic modeling. The experimental and simulation results of the proposed converter are carried out in a laboratory and through Matlab Simulink, where 10 V is given as an input voltage, and at the output, 100 V achieved in the proposed converter. A comparative analysis of the proposed converter has also been done with a conventional quadratic converter that has similar parameters. The results suggest that the proposed converter can obtain high voltage gain without operating at the maximum duty cycle and is more efficient than the conventional converter.
Effects of Sustainable Brand Equity and Marketing Innovation on Market Performance in Hospitality Industry: Mediating Effects of Sustainable Competitive Advantage

This study examines the effects of sustainable marketing assets, such as brand equity and marketing innovation, on market performance in the presence of sustainable competitive advantage as a mediator in the hospitality industry. Data were collected from hotel/restaurant customers (N = 360) on a Likert scale from 1= strongly disagree to 5 = strongly agree and analysis was conducted using the structural equation modeling (SEM) technique. The objective of this study is to understand the relationship among brand equity, marketing innovation, sustainable competitive advantage, and market performance in the hotel/restaurant industry. The results show that sustainable marketing assets have positive and significant effects on market performance. This study also demonstrates that sustainable competitive advantage fully mediates the relationship between brand equity and market performance while partially mediating the relationship between marketing innovation and market performance. The findings of this research can contribute to formulating effective marketing strategies for attracting customers, emphasizing sustainable issues in the hospitality sector, such as hotels/restaurants. This research adds practical value to the literature on brand equity, marketing innovation, sustainable competitive advantage, and market performance in the service industry.
Mechanism of the Innovation Development in the University

Emergence of the new education as a global phenomenon rather than a local or national one has been prompted by the awareness of the planetary scale of the environmental, economic and political challenges of the 21st century as well as by the ongoing trend toward the globalization of the economic, political and cultural life. For this reason, the elaboration of the mechanisms of the innovation development in the universities has become an urgent need of the modern society. In this case, the innovation development of a higher education establishment is perceived as a goal-driven process of the university transformation by means of building up the innovation infrastructure and integration of the education, science and business with the purpose of developing technologies of the future and, thus, acquiring new competencies by the mutual effort of the university staff, students and administration managing the educational process.
Fast Method Training Read the Qur’an Bilhikmah for the Tutor Candidate of the Mosque al-Furqan of UPI and the Mosque Around It

—It requires every Muslim to read the Quran. This is one aim of Islamic Religious Education (IRE) in higher education so that students can read the Quran. Only about 70% of students cannot achieve this educational goal. One reason, mistakenly applying the learning method. Bilhikmah is a fast method of reading the Quran, which is proven effective. This training activity aims to provide the Bilhikmah method to prospective tutors (instructors) of the Al-Furqan Mosque of UPI. The target is that 70% of 80 prospective tutors can implement this method. The training uses a variety of methods, namely presentations, questions and answers, demonstrations, practices, a small group guidance, and individual guidance. The results of the training almost all participants mastered this method. During the activity, the participants seriously listened to the advantages of this method. They also seriously practiced small groups on how to teach this method. Almost all trainees (90%) were then recruited to become tutors at the UPI Mosque. Thus, this training exceeded the target. Each of them then guided 10 tutorial participants. After being guided for three months, 7 out of 10 participants can read the Quran. The implication is that training on the Bilhikmah method needs to be continued in university mosques.
DEVELOPMENT OF GENOMIC RESOURCES TO STUDY APHID RESPONSE TO PLANT DEFENSES AND SYMBIOSIS WITH BUCHNERA APHIDICOLA

Background: The green peach aphid, Myzus persicae (Sulzer), is a world-wide insect pest capable of infesting more than 40 plant families, including many crop species. However, despite the significant damage inflicted by M. persicae in agricultural systems through direct feeding damage and by its ability to transmit plant viruses, limited genomic information is available for this species. This chapter has been published in BMC Genomics, 2007 Nov 16;8:423
Enhanced Kramers-Kronig Single-Sideband Receivers

Theoretically, Kramer–Kronig (KK) receivers are able to fully cancel signal-signal beat interference (SSBI), which results from a field-modulated single-sideband (with carrier) transmitter being used with a direct-detection receiver. However, even for strong carriers, which should meet the minimum-phase (MP) condition, bits are frequently erroneous. In this article, we simulate two methods of reducing error rates for weak carriers. The first is to limit the minimum value of the received signal, so that strong negative-going peaks are not produced by the logarithm function of the KK's ‘correction path’. The second is to replace the square-root function in the main signal path with a logarithmic function. This is to allow analog processing using semiconductor diodes. Our numerical simulations show that grossly approximating the square-root function is actually beneficial to the system, as it reduces the power in the signal close to the clipping events. When both the first and second techniques are combined, low error rates can be obtained at 2-dB less carrier power than for conventional processing, and 0.25-dB better receiver sensitivity. When 100-km of standard fiber is included, the carrier can be reduced by 3 dB, and the system has a 0.18 dB better sensitivity, and potentially supports analog processing. This work suggests that there may be other improvements possible, in signal quality and computational load, by moving away from a theoretically perfect implementation of the KK algorithm.
Implementación de nuevas políticas en tecnología (I+D+I) en las capacidades operativas de la fuerza de submarinos

The conversion of raw materials into sophisticated products has been a process that has become a generator of substantial wealth for industrialized nations, opposed to the primary production of developing countries. The policies generated by government agencies of the great economic powers are generally based on the manufacture of systems that are product of Research, Development and Innovation (R+D+I), unleashing a great educational impulse since it increases the level of knowledge of its population. These equipment and systems are sold to non-industrialized countries at high costs, so a technological dependence is generated that favors the manufacturer. The Armed Forces are aware of these difficulties, which is why in the case of Peru, we maintain a high degree of subordination in the different equipment that serve as components in our naval platforms. Globalization has generated the opening of trade, markets, information, among others, that is why technology is so reachable and we ha to generate Research, Development and Innovation (R+D+I) policies that allow us to reduce this dependence in which we are immersed. As the case of the Peruvian Navy and specifically with the Submarine Force, these knowledge efforts lead to improving its Operational Capabilities.
Histidine and tyrosine decarboxylase activities of lactic acid bacteria in sea bream (Sparus aurata) and sea bass (Dicentrarchus labrax)

Biogenic amines (BAs) are formed by decarboxylation of amino acids, amination and transamination of aldehyde and ketone groups. The excess of BAs is harmful to human health. BAs play a significant role in determining the shelf life and quality of foods. Released type and amount of BAs depend on factors such as the quality of the raw material, the diversity of natural microbiota, processing and storage conditions. In fish, the release of BAs is affected primarily from microbial growth as well as other reasons and may cause poisoning. It was aimed to determine the possibility of histidine decarboxylase activity gene (hdc) and tyrosine decarbocylase activity gene (tyrdc) in lactic acid bacteria (LAB) which were isolated from sea bream and sea bass. A total of 18 Gram positive-catalase negative LAB was isolated from 84 fish samples from 14 different fish markets. It was found that 12 out of 18 LAB (67%) isolates showed negative histidine and tyrosine decarboxylase activities. While 2 out of 6 (11%) LAB isolates were determined positive only tyrosine decarboxylase and 4 of them (22%) were positive for histidine and tyrosine decarboxylase. As a result of the Polymerase Chain Reaction (PCR), 9 out of 12 LAB isolates (75%) were found to have histidine decarboxylase activity gene. As a result, the prevalence of histidine decarboxylase activity gene in the LAB has detected more extensive than tyrosine decarboxylase activity gene. Increasing the studies examining the presence of aminobiogenic microorganisms in fish is important for the protection of public health.
A grad-div stabilized projection finite element method for a double-diffusive natural convection model

Abstract In this article, a grad-div stabilized projection finite element method is proposed for the double-diffusive natural convection model. Moreover, for the presented method, the stability analysis, and error estimates are deduced. Finally, numerical tests are provided that demonstrate the efficiency of the method. It is found that the presented method can improve the accuracy of the solution compared with the standard projection method, and compute approximations with better mass conservation.
Perilaku memiliki tabungan pendidikan anak

A form of parental responsibility for the continuity of their children's education is to prepare children's education funds from early ages. This study aims to examine the determinants of the intention to have children's education savings including; financial knowledge, risk tolerance, future financial orientation, social influence and their effect on the behavior of having children's education funds. The sample of this study involved 192 parents who had children under five years old and or children who are currently attending school education in Sidorejo District, Salatiga. Data was collected by the field survey method and analyzed using Structural Equation Modeling (SEM). The study results showed that financial knowledge, future orientation and social influence affected the intention to have educational savings. Further, the intention affected the behavior of having educational savings. However, the facilitating conditions such as the existence of bank institutions do not strengthen the influence of intention on behavior. This study contributes by not only broadening insights on education savings from a behavioral perspective but also by offering practical implications for policy makers and banking institutions in order to encourage public interest in having education savings so that the sustainability of children's education in terms of financing will be more secure.
Genetics as a Route toward Mucosal Vaccine Development

A goal in vaccinology is to obtain fully antigenically defined vaccines that can be delivered via mucosal routes, thus avoiding the requirement for injections with needles. Mucosal presentation of some antigens induces a tolerance effect on the immune system when the same antigen is subsequently administered systemically. This phenomenon may be controlled by mechanisms which have evolved to limit potentially damaging immune responses to dietary antigens. Thus, the immune system may be able to partially discriminate between dietary antigens and antigenic components of pathogens. The immune system is also organized into compartments associated with different tissues of the body. The majority of antigens are poor mucosal immunogens. In practical terms, potentially the quickest route toward the development of mucosal vaccines is the use of attenuated variants of mucosal pathogens. Genetic analysis of the genes required for Salmonella virulence has uncovered an array of different genes covering a wide range of functions. The construction of candidate human vaccine strains requires the use of precise gene replacement systems in order to ensure that any introduced mutation is fully characterized. A number of different bacteria have been considered for use as antigen delivery systems, including members of the genera Salmonella and Yersinia. Genetic instability has been a major problem encountered with the use of live Salmonella vaccines for the expression of heterologous antigens. Cholera enterotoxin (CT) and CT-B are potent mucosal antigens. Studies are under way to determine the characteristics of the protein that contributes to this property.