Miracle-dz/UniFAR-FTUs huggingface dataset:
Cross-Platform Web Framework for Gaze Tracking New opportunities for mobile interaction

Gaze tracking functionalities provide a new way of interacting with electronic devices. As things are now, they are often limited to one specific device and require proprietary hardware and software. We propose a solution for web applications to counteract those limitations. By using the latest web technologies, we ensure platform independence. Due to the design and modularity of our solution, gaze tracking solutions become interchangeable. Web applications can easily consume gaze data provided by a generic event-based webinterface. The main contribution of this work is a universal calibration and mapping functionality. The raw data of miscellaneous gaze trackers can be processed and transformed, so that the gaze points are stabilized and correctly mapped onto screen coordinates. In the present paper, we describe the three-layer-architecture we use. Our work shows how to combine recent web technologies and algorithms to supply gaze tracking functionalities in a generic way. Keywords-Gaze tracking; cross-platform; calibration; eye tracking; gaze events; interaction; gaze-enhanced web; elearning; real-time; adaptivity; adaptive e-learning
PREVENTABLE ADVERSE EVENTS.docx

Patient safety in healthcare improvement and quality involves a wide range of activities to meet ever-increasing demands, which involves multiple stakeholders focused on healthcare safety, efficiency, and ethical outcomes. Healthcare in the United States and countries represented by the World Health Organization (WHO) are actively engaged in health reform processes to improve health care quality initiatives. Despite increased advances in healthcare initiatives, in particular as it relates to standard organizational safety practices, failures continue to result in serious reportable medical or diagnostic errors. Health organizations focused on acute care and outpatient services are continuously confronted by material and human barriers to effective health team participation and accountability to meet the growing demands in healthcare, such as best practice education of health professionals, data collection and reporting. Professional roles are evolving in medicine and nursing with quality at the center of health system reform and trends to promote safe outcomes. This article will discuss the definitions of patient safety in detail and the classification of various types of medication and diagnostic errors, which are both preventable and not. There will be an emphasis on the different recommendations and methods on how to improve the major problems in healthcare. TARGET AUDIENCE AND LEARNING OBJECTIVES: The target audience for this course is nurses and advanced practice nurses or other licensed health providers interested in issues of quality healthcare. Course learning goals for the learner includes being able to: 1. Explain the different medical errors and interventions intended to reduce them. 2. Differentiate between a preventable vs. non-preventable adverse event. 3. Identify processes to investigate the extent of drug-related medical errors. 4. Explain the different barriers in hands off-transfers by medical professionals. 5. Describe patient chart review processes of errors recorded by healthcare providers. 6. Identify the extent of inappropriate prescription to both child and adults. 7. Explain the importance of the Agency for Healthcare Research and Quality (AHRQ) reports on patient safety and of accepted AHRQ Hospital Patient Safety Indicators (HPSI). 8. Identify the common types of adverse events of post-discharge patients and recommendations to improve them. 9. Explain processes to investigate diagnostic errors in both clinical and hospital settings to detect the warning signs for possible errors, and ways to improve it. 10. Describe the key elements of electronic health records, and its importance to information flow between patients and healthcare providers.
Chapter 1 Evaluating evidence of mechanisms in medicine Principles and procedures

This chapter presents heuristics for assessing evidence of mechanisms when evaluating effectiveness in medicine. The problem of evaluating effectiveness is broken down into two sub-problems: evaluating efficacy and evaluating external validity. In each case, we develop a three-step procedure for handling evidence of mechanisms: (i) collecting evidence of mechanisms; (ii) evaluating evidence of mechanisms; (iii) combining this evaluation with an evaluation of evidence of correlation in order to produce an overall assessment of causality. Appendices provide appraisal tools to assist with the assessment of evidence of mechanisms and discuss particular applications.
MV-Sports: A Motion and Vision Sensor Integration-Based Sports Analysis System

Recently, intelligent sports analytics is becoming a hot area in both industry and academia for coaching, practicing tactic and technical analysis. With the growing trend of bringing sports analytics to live broadcasting, sports robots and common playfield, a low cost system that is easy to deploy and performs real-time and accurate sports analytics is very desirable. However, existing systems, such as Hawk-Eye, cannot satisfy these requirements due to various factors. In this paper, we present MV-Sports, a cost-effective system for real-time sports analysis based on motion and vision sensor integration. Taking tennis as a case study, we aim to recognize player shot types and measure ball states. For fine-grained player action recognition, we leverage motion signal for fast action highlighting and propose a long short term memory (LSTM)-based framework to integrate MV data for training and classification. For ball state measurement, we compute the initial ball state via motion sensing and devise an extended kalman filter (EKF)-based approach to combine ball motion physics-based tracking and vision positioning-based tracking to get more accurate ball state. We implement MV-Sports on commercial off-the-shelf (COTS) devices and conduct real-world experiments to evaluate the performance of our system. The results show our approach can achieve accurate player action recognition and ball state measurement with sub-second latency.
Aging renewal theory and application to random walks

The versatility of renewal theory is owed to its abstract formulation. Renewals can be interpreted as steps of a random walk, switching events in two-state models, domain crossings of a random motion, etc. We here discuss a renewal process in which successive events are separated by scale-free waiting time periods. Among other ubiquitous long time properties, this process exhibits aging: events counted initially in a time interval [0,t] statistically strongly differ from those observed at later times [t_a,t_a+t]. In complex, disordered media, processes with scale-free waiting times play a particularly prominent role. We set up a unified analytical foundation for such anomalous dynamics by discussing in detail the distribution of the aging renewal process. We analyze its half-discrete, half-continuous nature and study its aging time evolution. These results are readily used to discuss a scale-free anomalous diffusion process, the continuous time random walk. By this we not only shed light on the profound origins of its characteristic features, such as weak ergodicity breaking. Along the way, we also add an extended discussion on aging effects. In particular, we find that the aging behavior of time and ensemble averages is conceptually very distinct, but their time scaling is identical at high ages. Finally, we show how more complex motion models are readily constructed on the basis of aging renewal dynamics.
ICT-Design in a Complex Moral Universe – Ethnography-based Development of a GPS Monitoring System for Persons who Wander

Increasing life expectancy and reduced birth rates as results of the recent demographic changes is linked to drastic changes in respect to age structures. The amount of persons over 80 will double until 2025 and at the same time, the availability of care workers in the care sector will be reduced. That’s why the ageing societies are facing enormous challenges which are linked to higher age, such as the increase of chronic conditions, reduced physical and mental capabilities and the risk of social isolation and reduced autonomy (EU Summit 2015).
Unique effect and clinical evidence of SparkWaveTM therapy in the treatment of erectile dysfunction

Introduction—Low-energy shockwave therapy (LESWT) has been shown to improve erectile function in patients suffering from diabetes mellitus (DM)-associated erectile dysfunction (ED). However, the underlying mechanism remains unknown. Aim—To investigate whether LESWT can ameliorate DM-associated ED in a rat model, and examine the associated changes in the erectile tissues. Methods—Newborn male rats were intraperitoneally injected with 5-ethynyl-2-deoxyuridine (EdU, 50mg/kg) for the purpose of tracking endogenous mesenchymal stem cells (MSCs). Eight weeks later, 8 of these rats were randomly chosen to serve as normal control (N group). The remaining rats were injected intraperitoneally with 60 mg/kg of streptozotocin (STZ) to induce DM. Eight of these rats were randomly chosen to serve as DM control (DM group) while another 8 rats were subject to shockwave treatment (DM+SW group). Each rat in the DM+SE group received 300 shocks at energy level of 0.1mJ/mm2 and frequency of 120/min. This procedure was repeated three times a week for two weeks. Another two weeks later, all 24 rats were evaluated for erectile function by intracavernous pressure (ICP) measurement. Afterward, their penile tissues were examined by histology. Main Outcome Measures—Erectile function was measurement by ICP. Neuronal nitric oxide synthase (nNOS)-positive nerves and the endothelium were examined by immunofluorescence (IF) staining. Smooth muscle and MSCs were examined by phalloidin and EdU staining, respectively. Results—STZ treatment caused a significant decrease in erectile function and in the number of nNOS-positive nerves and in endothelial and smooth muscle contents. These DM-associated deficits were all partially but significantly reversed by LESWT. MSCs (EdU+ cells) were significantly more numerous in DM+SW than in DM rats. Conclusions—LESWT can partially ameliorate DM-associated ED by promoting regeneration of nNOS-positive nerves, endothelium, and smooth muscle in the penis. These beneficial effects appear to be mediated by recruitment of endogenous MSCs. *Corresponding Author: Department of Urology, University of California, San Francisco, CA 94143-0738, USA Phone: 415-476-3800 Fax: 415-476-3803 clin@urology.ucsf. edu. #These authors contributed equally to this study Conflict of Interest: None NIH Public Access Author Manuscript J Sex Med. Author manuscript; available in PMC 2014 March 01. Published in final edited form as: J Sex Med. 2013 March ; 10(3): 738–746. doi:10.1111/jsm.12024. N IH PA Athor M anscript N IH PA Athor M anscript N IH PA Athor M anscript
Persistence of Altruistic Community under Indiscriminate Altruism YING-HEN

The evolution of indiscriminate altruism in animal populations is examined using coupled Von Foerster equations. Analytic expression for the gene frequency of altruists is derived. We also obtain formulas for the numbers of the altruistic and nonaltruistic groups at each generation in terms of the agedependent ratio of altruists in the population during each geneiation, fn(a). We then use our results to demonstrate the distinction between the evolution of altruism and the survival of an altruistic society, and our discussion is then illustrated with simulated examples.
Controlled Preparation and Surface Structure Characterization of Carbon-Coated Lithium Iron Phosphate and Electrochemical Studies as Cathode Materials for Lithium Ion Battery

Amo rphous carbon-coated lithiu m iron phosphate (C-LiFePO4) particles have been mass synthesized at the commercial scale by a controlled solid-state reaction method. Particles morphologies , o livine-type phase structures and the carbon coating features were investigated in details by various techniques as X-ray diffraction analysis (XRD), scanning electron microscopy (SEM) imaging, and transmission electron microscopy (TEM, HRTEM ) imag ing, selected-area electron diffraction (SAED), X-ray energy dispersive spectroscopy microanalysis (XED S), and X-ray photoelectron spectroscopy (XPS). Single-crystal nature of the olivine type LiFePO4 structures was revealed by XRD and SA ED analyses. TEM imaging showed rough nanoparticles spherical features with average size range of 50-200 n m. Ho mogenous coating features of carbon layers on the particles surface and olivine-LiFePO4 phase are clearly observed in HR-TEM imaging and confirmed by the corresponding SAED pattern. Elemental b inding energy fro m XPS analysis also confirmed that an amo rphous sp2 carbon coating layer and olivine type LiFePO4 structures. It is indicated that the characteristics of sp2 type conducting-coating layer on the particles surfaces gave rise to improved electrical conductivity by reducing the diffusion path of the electron and lithiu m ions, as directly evidenced fro m our charge-discharge cycling testing as the cathode in the Lithiu m ion battery cell.
Exercise Intensity during Treadmill Walking with Gait-Patterned FES among Patients with Incomplete Spinal Cord Injury: Case Series

Purpose. To determine the feasibility of increasing the cardiopulmonary exercise intensity during walking with gait-patterned functional electrical stimulation (GP-FES) among individuals with motor incomplete SCI. Methods. Two men with motor-incomplete SCI (Subjects A and B, age 45 and 50 years; Level of Injury: C4 and T10; AIS score: D and D, resp.) performed a three sequential four-minute continuous walking sessions [(1) regular gait (non-GP-FES-1); (2) gait with GP-FES (GP-FES); (3) regular gait (non-GP-FES-2)]. Oxygen consumption (Vo2) was measured continuously during trials. Results. Vo2 was higher during GP-FES (Subjects A and B; 14.5 and 19.1 mL/kg/min, resp.) as compared to regular gait (Non-GP-FES-1: Subjects A and B; 13.4 and 17.0: mL/kg/min, resp.; non-GP-FES-2: Subjects A and B; 13.1 and 17.5: mL/kg/min, resp.). Conclusion. The exercise intensity of GP-FES walking was higher than that of regular walking among individuals with motor incomplete SCI. Further investigations are required to determine the clinical relevance of the exercise.
PYOCYANIC BACILLUS PROPAGATION SIMULATION

Nosocomial diseases are pathologies that appear during medical care that were not present at patient admission. Being able to simulate the propagation of such diseases inside an hospital and to track them is therefore important to fight and avoid them. The Pyocyanic Bacillus is a frequent example of such a disease. It is important to understand how such bacteria propagate since more and more of their strains become antibiotic resistant. Therefore we must not only be able to treat them, but also to block their diffusion to avoid them. The work presented here consist in a simulation of the propagation of pyos inside an hospital taking spatial problems into account, and allowing to better understand the infection diffusion mechanisms and to propose some means to circumvent it. The simulation considers both the spacial representation of the hospital, and the different actors, healthcare workers, patients and visitors.
Parametric instability of the interface between two fluids

The flat interface between two fluids in a vertically vibrating vessel may be parametrically excited, leading to the generation of standing waves. The equations constituting the stability problem for the interface of two viscous fluids subjected to sinusoidal forcing are derived and a Floquet analysis is presented. The hydrodynamic system in the presence of viscosity cannot be reduced to a system of Mathieu equations with linear damping. For a given driving frequency, the instability occurs only for certain combinations of the wavelength and driving amplitude, leading to tongue-like stability zones. The viscosity has a qualitative effect on the wavelength at onset: at small viscosities, the wavelength decreases with increasing viscosity, while it increases for higher viscosities. The stability threshold is in good agreement with experimental results. Based on the analysis, a method for the measurement of the interfacial tension, and the sum of densities and dynamic viscosities of two phases of a fluid near the liquid-vapour critical point is proposed.
RECENT TRENDS IN MALE REPRODUCTIVE HEALTH PROBLEMS

This review critically evaluates the current trends of male reproductive health problems in relation to semen quality. Increasing trend in male reproductive disorders observed in recent years, are principally found to associate with lifestyle and environmental factors. Lifestyle-allied diseases could be controlled with modification in diet, living and working environment etc. This review outlines the changing trends in male reproductive health and highlights the alterations in semen quality, in scientific manner. Though scientific and public concern regarding the changes on male reproductive health has grown in past few decades but the demonstration of a geographical differences in sperm concentration, still appears to be controversial. The amplitude of the difference observed cannot only be explained by methodological or confounding factors, and must to some extent be attributed to ethnic, genetic or environmental factors. However, there are numerous reports indicating the chronologically declining sperm count and standard semen parameters in various population indicating the increasing trend of male reproductive health disorders.
A Methodology for Systematic Volumetric Analysis of Perioperative Cranial Imaging in Neurosurgical Patients

Background Although objective assessment of perioperative imaging provides a rigorous evaluation method of neurosurgical techniques in epilepsy, its use remains far from mainstream. Open surgery remains the gold standard for treatment of mesial temporal lobe epilepsy (MTLE); however, stereotactic laser ablation is a promising minimally invasive alternative. Nevertheless, the variables that may affect seizure outcome in stereotactic laser amygdalohippocampectomy (SLAH) remain unclear. While an objective endpoint such as ablated mesial temporal volumes may be significant, a standard methodology for calculating such volumes has yet to be proposed.
Racial/Ethnic Disparities in Diabetes Care and Outcomes: A Mixed Methods Study

Limited research has examined racial/ethnic differences in diabetes care and outcomes among primary care patients. This study examined racial/ethnic differences in diabetes care and outcomes among an ambulatory patient population and explored patient perceptions of the patient-provider relationship to inform strategies to improve care delivery. Using data from 62,149 adults with diabetes who received care within Atrium Health in 2013, regression models assessed associations between race/ethnicity and the following outcomes: glycated hemoglobin (HbA1c) tests, low density lipoprotein (LDL) and blood pressure (BP) screening, foot and eye exams, and HbA1c, LDL, and BP control. Eleven patients with diabetes and uncontrolled hypertension participated in three focus groups about their perceptions of the patient-provider relationship. Compared to non-Hispanic Whites, non-Hispanic Blacks had 22% to 73% higher odds of receiving screenings (HbA1c, LDL, BP, foot and eye exams; p<0.05) and 25% to 36% lower odds of HbA1c, LDL or BP control (p<0.05). Focus group participants indicated that good communication and continuity in their relationships with providers played a key role in management of their diabetes. Findings suggest that strategies to strengthen partnerships between patients and their clinical teams, increase self-management support and utilize shared-decision making may help to improve outcomes for minority
Axon guidance repulsant SEMA3F increases chemosensitivity to oxaliplatin and inhibits epithelial-mesenchymal transition of colorectal cancer cells

Background: Our previous study has shown that down-regulation of axon guidance repulsive Semaphorin-3F (SEMA3F) promotes growth and metastasis of colorectal cancer (CRC) cells. However, the role of SEMA3F in chemosensitivity and epithelial-mesenchymal transition of CRC cells remains unknown. Methods: The expression of SEMA3F, P-gp, GST-π and TOPO-II in CRC tissues from 94 patients was determined by immunohistochemical staining. Knock-down of SEMA3F was achieved by lentivirus transfection. Functional assays were done to evaluate the invasion, apoptosis and cell viability. Results: We found that the expression of SEMA3F is negatively correlated with the expression of P-gp and GST-π in CRC tissues from 94 patients. Knock-down of SEMA3F significantly decreased apoptosis of HCT116 and SW480 cells, accompanying with up-regulation of anti-apoptotic BCL-2 and down-regulation of pro-apoptotic BAD and BAX. In addition, knock-down of SEMA3F attenuated chemosensitivity to oxaliplatin of CRC cells. Moreover, we found that down-regulation of SEMA3F promotes epithelial-mesenchymal transition of HCT116 and SW480 cells by decreasing the expression of epithelial marker E-cadherin, and increasing the expression of mesenchymal marker Slug, Snail and Vimentin. Finally, knock-down of SEMA3F increased the tumor volume and decreased overall survival of nude mice using colorectal cancer orthotopic xenograft model under the treatment of oxaliplatin. Conclusions: SEMA3F increases chemosensitivity to oxaliplatin and inhibits epithelial-mesenchymal transition of CRC cells.
Constructing software for analysis of neuron, glial and endothelial cell numbers and density in histological Nissl-stained rodent brain tissue

Cell number, density and volume of white and gray matter in brain structures are not constant values. Cellular alterations in brain areas might coincide with neurological and psychiatric pathologies as well as with changes in brain functionality during selection experiments, pharmacological treatment or aging. Several softwares were created to facilitate quantitative analysis of brain tissues, however results obtained from these softwares require multiple manual settings making the computing process complex and time-consuming. This study attempts to establish half automated software for fast, ergonomic and an accurate analysis of cellular density, cell number and cellular surface in morphologically different brain areas: cerebral cortex, pond and cerebellum. Images of brain sections of bank voles stained with standard cresyl-violet technique (Nissl staining), were analyzed in designed software. Results were compared with other commercially available tools regarding number of steps to be done by user and number of parameters possible to measure.