Miracle-dz/UniFAR-FTUs huggingface dataset:
Lessons learned in Central Ghana regarding the pandemic influenza a vaccine and how they could be used conserving new ebola virus vaccine

Background: The emergence of influenza A (H1N1) virus prompted the development of influenza A (H1N1) monovalent vaccines (2009-H1N1). The use of the vaccine was recommended by the Center for Disease Control and Prevention Advisory Committee on Immunization Practices. Adverse events after vaccinations occur but are generally rare. The study was carried out to identify reported adverse and serious adverse events after administration of an influenza A (H1N1) vaccine. Method: This cross-sectional study was carried out between mid of July 2010 to end of August 2010 in Kintampo North Municipality and Offinso South Municipality in Ghana. The study was carried out as part of a pharmacovigilance study in Kintampo Health Research Centre (KHRC). Data were collected from consented participants using questionnaire. Results: Of the 420 forms that were given out to consented participants in the two regions, 379 (90.2%) were returned with completed information related to the Influenza A (H1N1) vaccine. Participants who took the vaccine reported of adverse events such as fever, headache, chills, stomach ache, diarrhoea, pain in the heart and fast heartbeat. Of those who received the vaccine, 4.4% (16/366) were hospitalized for the adverse event they reported to have experienced after vaccination. Of the 4.4% of the vaccinated participants that were hospitalized, 43.8% (7/16) were males and 56.3% (9/16) were females. There was no difference between the proportions (p=0.97) of males and females that were hospitalized after vaccination. Conclusion: Ghana used PandemrixInfluenza A (H1N1) vaccine in June 2010. Symptoms reported ranged from what were expected to unexpected symptoms. This survey recorded sixteen (16) hospitalizations due to symptoms reported after vaccination. The study was not controlled and therefore could not make claims of whether the serious adverse events were associated with the vaccine. We recommend continuous and effective post-vaccination and post-marketing monitoring of adverse events after vaccinations. *Correspondence to: Dennis Adu-Gyasi, Kintampo Health Research Centre, P. O. Box 200, Kintampo North, Ghana, E-mail address: adugyasidennis@yahoo.co.uk
A Data-Driven Approach to Exploring Future Land Use and Transport Scenarios: The Online What If? Tool

ABSTRACT In an era of rapid urbanization, there is a need for data-driven tools to guide long-term strategic planning. Online What If? (OWI) is a planning support system (PSS) that helps inform strategic planners about the impact of population growth and other socioeconomic factors will have on the future growth of cities. This research presents its application in metropolitan Perth with a two-part case study, demonstrating a first comprehensive application of the tool. First, OWI tests five scenarios for urban growth through the year 2050, allocating residential land use. Next, OWI alters land use allocations to align residential development with high frequency public transit, while also allocating commercial land use to support higher residential densities. Together, these data-driven scenarios inform city planners and policy makers in guiding the long-term, sustainable growth of Perth. The paper concludes with a review of OWI’s strengths, weaknesses and possibilities for continual development.
Larvicidal activity of lectins on Lucilia cuprina: mechanism of action

Larvae of the blowfly Lucilia cuprina (Wied.) (Diptera: Calliphoridae) were grown in vitro on a serum‐free medium in the presence of a number of lectins. Lectins with specificities for β‐(1,4)‐N‐acetylglucosamine (wheat germ lectin) and α‐D‐mannopyranosyl and (α‐D‐glucopyranosyl residues (lentil lectin and Con A) caused strong concentration‐dependent inhibition of the growth of the larvae and substantial mortality. Wheat germ lectin had the strongest effects, showing 50% inhibition of larval growth at a concentration of 2 μM and 100% mortality at 25 μM. Other lectins with different sugar specificities had much less effect. The mechanism of the larvicidal action(s) of wheat germ lectin, lentil lectin and Con A was investigated. There were at least three effects of these lectins on L. cuprina larvae. First, these lectins bound to and reduced the permeability of the peritrophic membrane of the larvae. Second, they reduced ingestion of diet medium by larvae. Third, the lectins also bound to the apical membranes of larval gut epithelial cells although there were no obvious signs of damage to these cells. It is concluded that the combination of these effects probably results in the starvation of the larvae. The implications of these results in terms of possible control strategies for L. cuprina are discussed.
Interactions between a Buffered Amine Oxide Impregnation Carrier and an Acrylic Resin, and Their Relationship with Moisture

Wood used outdoor is subjected to different sources of degradation and should be protected properly. In this study, acrylic resins were added to a wood impregnation system using amine oxides and propiconazole, an organic fungicide, to create a two-part wood protection preservation treatment. Since amine oxides can diffuse readily into wood, this treatment protected both the surface and inner structure of the treated wood following a simple dipping. Many aspects of the treatment were studied: the adhesion of the acrylic coatings, their permeability to water, and the impregnation depth of the propiconazole. In each case, a particular attention was accorded to the interactions between the resins and the impregnation system. Adhesion and permeability tests were coupled with an artificial aging process simulating severely wet conditions. Amine oxides reduced the adhesion of the coatings but did not impair their aging properties. Because of their hydrophilic nature, they also increased the permeability to liquid water, although they did not affect the air moisture permeability. The penetration of the propiconazole, estimated with a dye, decreased with the resin. Overall, the two parts of the treatment lightly impaired each other, but the practical aspect of this treatment may overcome these disadvantages.
Sphingolipids in Toxoplasma gondii; synthesis and scavenging

Toxoplasma gondii is a globally endemic parasite which can cause severe illness in animal livestock and humans. Currently there are no effective drug treatments which do not have severe side effects and therefore the search for new drugs is of significant importance. Sphingolipids have been shown to be essential in many different eukaryotic cell types through their roles in cell signaling and regulatory roles in cell transport. Serine palmitoyltransferase is the first rate limiting step in biosynthesis and the inhibition of this enzyme has proved lethal in many organisms. This enzyme is currently uncharacterized in T.gondii and other Apicomplexa. In this work the evolutionary origins, function and the cellular localization of this protein were investigated. Further to this, endocytosis assays were also performed on extracellular tachyzoites to investigate the potential of the parasite to scavenge complex sphingolipids.
Justicia Organizacional y su Incidencia en la Satisfacción Laboral del personal de las Instituciones Públicas del Cantón Bolívar

The objective of this study is to determine how Organizational Justice affects Labor Satisfaction of personnel that works in canton Bolivar’s Public Institutions in Ecuador. Through survey monkey, a questionnaire was applied that was individually answered by a sample of 286 people working in different areas of four public entities of canton Bolívar, using Colquitt’s Organizational Justice scales and the Minnesota Satisfaction Questionary. Results indicated that there is a clear relationship between what people perceive as fair and unfair and the satisfaction they perceive about their work within canton Bolívar’s public institutions.
Research on Current-Limiting Control Strategy Suitable for Ground Faults in AC Microgrid

On August 9, 2019, a blackout event with significant impacts occurred in the British power grid (BPG). The technical report submitted by the BPG points out that the accident originated from multiple independent and concurrent events, resulting in a sudden power shortage, which exceeded the fortification requirements of the relevant standards. This incident has led us to reflect on some of the technical bottlenecks that exist in the high-proportion renewable energy system, such as frequency oscillations, security defense of large power grid, current-limiting, and so on. Based on this background, this article studies a strong current-limiting control system suitable for ground faults in ac microgrid, which can limit the fault current to less than twice the rated current so that the distributed generators can go through multiple faults ride-through without offline operation. Meanwhile, this control system does not need to switch the reference inductance current between normal and faults and can realize the smaller current harmonics and lower asymmetry amplitudes in the two states. Simulation and experiment show that the method proposed in this article can adapt to a variety of ground faults.
Home Cultures and Idiom Processing: A Short Cut to Encyclopaedic Assumptions of Idioms

This paper forms a part of my PhD research on idiom comprehension and processing through home cultures. The article argues that using home cultural assumptions in teaching idioms could result in easy and quick processing of such figurative aspects of speech. Shedding light on the nature of teaching, however, reveals that teaching English in Algeria is a fairly target culture-based process. This can slow the comprehension process and on some occasions, confuse the learner. This paper reveals the results of a set of semistructured interviews and comprehension tests that were conducted with teachers and learners. Learners were divided into two groups and taught throughout a four-week period using teaching materials that assumed home and target culture lessons of idioms, respectively. Students sat for a pre- and a post-test and were also interviewed after finishing the lessons. The results revealed that students recorded positive reactions toward home culture based teaching of idioms. Comprehension tests also reported a significant difference between the two groups’ performance on idiom comprehension.
Residual Core Maximization: An Efficient Algorithm for Maximizing the Size of the k-Core

In many online social networking platforms, the participation of an individual is motivated by the participation of others. If an individual chooses to leave a platform, this may produce a cascade in which that person’s friends then choose to leave, causing their friends to leave, and so on. In some cases, it may be possible to incentivize key individuals to stay active within the network, thus preventing such a cascade. This problem is modeled using the anchored k -core of a network, which, for a network G and set of anchor nodes A , is the maximal subgraph of G in which every node has a total of at least k neighbors between the subgraph and anchors. In this work, we propose Residual Core Maximization (RCM) , a novel algorithm for ﬁnding b anchor nodes so that the size of the anchored k -core is maximized. We perform a comprehensive experimental evaluation on numerous real-world networks and compare RCM to various baselines. We observe that RCM is more eﬀective and eﬃcient than the state-of-the-art methods: on average, RCM produces anchored k -cores that are 1 . 65 times larger than those produced by the baseline algorithm, and is approximately 500 times faster on average.
THE CLINICAL ROLES OF PSYCHOLOGISTS IN END-OF-LIFE CARE: A NEW HORIZON IN INDIAN PALLIATIVE CARE

Among all the various existing skills needed in palliative end-of-life care, none is more important the ability to communicate effectively. Terminal ill experience is the time when patients were overwhelmed with several emotional and psychological symptoms, which need the maximum amount of care, through effective communication in the most appropriate way. Effective communication is the fundamental component to physician and patient quality relationship, which make clinician to be trusted by the patient, resulting in quality decision making for patient treatment and future diagnosis plan in the clinical practices. However, looking at the present scenario of Indian health care system, the absence of good communication is visible in most of the clinical practices, which becomes the underlying reason for terminal patient receiving unwanted life sustaining medical treatment, along with inappropriate care that goes against the patient’s choices. Moreover, effective communication also plays an important role in breaking the bad news to patient and family. Thus, seeing at the urgent needs of effective communication in the clinical practices, the present study is forms through fieldwork that is follow up by an analytical study. The aim of this particular research is to inquire, how important the effective communication is in terminal care, and what are the strategies for breaking bad news effectively without hurting the feelings of the dying individual’s. REVIEW THE CLINICAL ROLES OF PSYCHOLOGISTS IN END-OF-LIFE CARE: A NEW HORIZON IN INDIAN PALLIATIVE CARE Vaiphei Suantak Demkhosei, Sisodia Devendra Singh Bhupal Nobles’ University, Department of Psychology, Udaipur, India
Comprehensive Analysis Method Based on Multi-attribute Fuzzy Granulation in Decision Evaluation

In order to solve the problem in the process of supplier selection and evaluation, in this paper, granular computing theory was applied to the supplier evaluation and selection with fuzzy algorithm and analytic hierarchy process (AHP) in this paper. By using attribute value discretization algorithm, the application domain is extended to the case where attribute value is quantitative, and the decision analysis method is constructed. This method combined the qualitative and quantitative information to build a comprehensive analysis method. It has constructed a decision analysis method to realize supplier evaluation and selection of multi-attribute group decisions based on concerns, so as to provide enterprises with appropriate suppliers. This paper was applied to the evaluation and selection model of suppliers to verify the accuracy and feasibility of the decision analysis method. The enterprise with appropriate suppliers was provided in this method, which strengthened the enterprise’s position in the supply chain, and then improved the core competitiveness.
Lactic acid fermentation of fresh and stored carrot : chemical, microbial and sensory evaluation of products

Carrots (Daucus carota) from the same harvest were divided into two batches. The first batch was lactic acid-fermented immediately after harvest, while the second batch was stored for 6 months before fermentation. Both batches were subjected to spontaneous fermentation, relying on the lactic acid bacteria occurring naturally on the carrot, and to controlled fermentation, using a Lactobacillus plantarum starter culture. When unfermented carrot was stored for a period of 6 months the amounts of free glucose and fructose decreased, while the amount of sucrose increased. The condition of the raw material is more important for the sensory and microbial qualities of the products than whether a starter culture is used to control the fermentation or not
How to stop the epidemic of chronic noninfectious disease

The greatest problem of modern health protection is chronic uninfectious diseases (CUD}. In the developed countries they come forward as reason more than in 80% of all cases of death. The stake of deaths is especially high from the diseases of the cardiovascular system, here is a permanent height of this index. The government and international programs (for example, CINDI) did not change a situation. Appeared, that a hope to improve the health of population due to conception of risk factors is illusive, because a fight against them does not diminish the amount of diseased. This conception answers a question “how” does not answer a question “why”. All anymore appears works in that a reasonable doubt speaks out concerning ability of traditional prophylactic approaches to influence on a general death rate [8, 9 and other]. Classic endogenous risk factors in a number of situations can come forward risk indicators, predicting the origin of illness, but their correction improves a prognosis not necessarily. In addition, there is the phenomenon ′′of pumping over of death rate′′[8], when the decline of death rate from one diseases is accompanied by the increase of death rate from other, not giving a result from the point of view of increase of life-span [13].
Enhancing Creativity: Using Visual Mnemonic Devices in the Teaching Process in Order to Develop Creativity in Students

(1) Background: In the field of creativity studies there is always space for expansion and new conceptualizations of the methods involved. Therefore, we will present in this paper a brief arrangement of the methods used to enhance creativity and consider whether visual mnemonic devices can increase creativity. The devices are used in the teaching process in order to ease the remembering process by creating a visual representation. Visual mnemonic devices are techniques that increase creativity as part of their own performance. (2) Methods: We will use a quasi-experimental, nonequivalent group design, the procedure involving the use of visual mnemonic devices. (3) Results: The results show that the degree of abstracting increased after using visual mnemonic devices, along with fluency and other creativity dimensions. (4) Conclusions: The paper shows that the creativity increased, based on a national percentile system (along with standard creativity index), after using the visual mnemonics devices, thus demonstrating a case for integrating the visual mnemonic devices among methods to foster creativity.
Personalizing the approach to asthma treatment

ABSTRACT Introduction: Personalized/precision medicine has changed the vision of respiratory diseases. Asthma is now recognized as a heterogeneous disease with different pathogenic mechanisms, clinical course, and different responses to different treatments. Areas covered: According to this vision, the prescription of treatments has become more tailored. Taking into account the clinical and molecular phenotypes and endotypes, the focus has moved to the predominant characteristics of the inflammatory process, the clinical aspects, and the study of the biological mechanisms. Eventually, researchers highlighted the presence and the etiological dignity of treatable traits defined as therapeutic targets identified by specific phenotypes or endotypes through validated biomarkers. Expert commentary: All these aspects involve a novel approach, with a ‘point-of-care’ assessment, that seems to be more and more central to warrant a forward-step to the personalization of asthma treatment. The availability of portable, hand-held devices to assess specific biomarkers, represents an additional advantage.
Mécanismes moléculaires de la régulation et de la dérégulation de l'épissage alternatif de Tau et cTNT dans la Dystrophie Myotonique de Type 1

La Dystrophie Myotonique de type I (DM1) est une maladie genetique a transmission autosomique dominante. Elle est due a une expansion pathologique de triplets CTG au sein de la region 3'UTR du gene DMPK. Les individus atteints de DM1 souffrent d'une atteinte multi-systemique, qui se caracterise, sur le plan moleculaire, par une alteration de l'epissage alternatif de plusieurs transcrits privilegiant l'expression d'isoformes foetales. L'hypothese physiopathologique majeure de la DM1 repose sur un gain de fonction toxique des ARNm mutes conduisant a des alterations de facteurs regulateurs d'epissage des familles Mbnl et CELF. Dans le cerveau de patients atteints de DM1, un defaut d'epissage alternatif du transcrit de Tau conduit a la surexpression de l'isoforme foetale avec, notamment, une exclusion preferentielle des exons 2 et 3. Ce defaut s'accompagne d'une agregation de la proteine, signe d'une degenerescence neuronale. Ainsi, le premier objectif de ce travail a ete de mieux connaitre les mecanismes moleculaires responsables du phenotype d'epissage pathologique de Tau dans la DM1. Nous nous sommes egalement interesses au transcrit de la Troponine T cardiaque (cTNT), transcrit exprime dans le coeur et dont l'alteration d'epissage avec la DM1 conduit a un profil d'epissage de type foetal. Concernant Tau, nos resultats montrent que le profil d'epissage foetal. , et en particulier, l'exclusion des exons 2 et 3, est un phenotype qui peut etre obtenu par differentes voies moleculaires impliquant differents elements cis regulateurs. Dans la DM1, ce phenotype resulte d'un mecanisme bien specifique. Pour l'exon 2, celui-ci semble impliquer un « silencer » intronique situe dans une region relativement loin en aval de l'exon. Cette meme region semble egalement medier l'effet du facteur d'epissage ETR-3, facteur appartenant a la famille CELF et qui favorise l'exclusion des exons 2 et 3. Pour ce qui est de la regulation de l'exon 5 de cTNT, celle-ci met en cause plusieurs elements cis regulateurs, tous localises dans les 150 nucleotides introniques encadrant l'exon. Parmi ces elements, on identifie un « silencer » et un « enhancer » en amont de l'exon et deux « enhancers » en aval. Nos resultats montrent qu'une region intronique en amont est indispensable a l'effet des expansions de CTG. De plus, dans cette region, nous avons identifie de nouveaux sites fonctionnels de fixation du facteur d'epissage Mbnl1 par rapport a ceux decrits dans la litterature. En conclusion, nos travaux mettent en evidence plusieurs elements cis regulateurs d'epissage alternatif de Tau et cTNT. Pour ces transcrits, les regions introniques en jeu dans l'effet des expansions de triplets CTG le sont egalement dans l'effet des facteurs Mbnl ou CELF. Ces resultats confortent l'hypothese physiopathologique des mecanismes de deregulation de l'epissage alternatif dans la DM1. Ils montrent egalement la specificite des mecanismes mis en jeu dans la pathologie, fournissant ainsi des cibles therapeutiques