Miracle-dz/UniFAR-FTUs huggingface dataset:
Морфологические и биохимические показатели крови у кроликов при применении пробиотического препарата велес 6. 59

The purpose of the study is change the effect of a dietary supplement to feed Veles 6.59 has as an active principle bacterium Lactobacillus plantarum strain VKPM B-2347, & Propionibacterium freudenreichii strain VKPM B-6561 on the basic parameters of morphological, & biochemical parametrs blood rabbits. To achieve this goal have been formed 2 experimental, & control groups of Soviet Chinchilla rabbits aged 45 days, & 5 animals in each group. The animals of the 1st, & 2nd test groups Veles 6.59 administered per os once a time a day at a dose of 0.25, & 0.5 ml/kg body weight for 30 days. Rabbits of the control group did not receive the drug. The animals were kept in cages in a room at a temperature of 13-18°C. Feeding was the same for all animals. Under the influence of probiotic preparation, as in the period of administration and after discontinuation in the blood of red blood cells and hemoglobin, total protein, albumin, β-, & γ-globulin, calcium and phosphorus content and decreased globulin within the physiological range. The maximum increase in total protein, albumin and γ-globulin celebrated on the 45th day of the experiment when using the drug in a dose of 50 ml/kg. With a longer-effect of the drug on the 90th day of the study recorded more pronounced changes of albumin, β-, & γ-globulins. Serum biochemical changes may indicate increased non-specific resistance and activation of mineral metabolism in rabbits. The drug has no negative side effects on the body of rabbits.
Cytokinins: Chemistry, Activity, and Function

Cytokinins are hormones involved in all aspects of plant growth and development and are essential for in vitro manipulation of plant cells and tissues. Much information has been gathered regarding the chemistry and biology of cytokinins, while recent studies have focused on the genetics and cytokinin-related genes. This text focuses on key subject areas of cytokinin - chemistry, biosynthesis, metabolism, activity, function, genetics and analyses. These areas are comprehensively reviewed in individual chapters by experts in the field. In addition, a personal history of the discovery of cytokinin is presented by Professor Folke Skoog.
Genetic Differentiation Between Western and Eastern (Eschrichtius Robustus) Gray Whale Populations Using Microsatellite Markers

Within the North Pacific, gray whales (Eschrichtius robustus) are recognized as distinct eastern and western populations. Although both populations were severely reduced by whaling, the eastern population is generally considered to have recovered while the western population has remained highly depleted. Previous studies have documented genetic differentiation between the two populations on the basis of mtDNA haplotype frequencies. Since mtDNA represents only maternal inheritance patterns, the present study used bi-parentally inherited microsatellite markers (n=13) to measure differentiation between populations as well as to compare levels of nuclear genetic diversity retained in each. Mean levels of genetic diversity, as measured by the microsatellites, were similar between the eastern and western populations, indicating that the western population has retained relatively high levels of nuclear genetic diversity despite its small size. Comparison of microsatellite allele frequencies confirmed that eastern and western populations are genetically distinct. Although highly statistically significant, the level of differentiation between the two populations is relatively low, and sex-specific analyses suggest that some amount of male-biased dispersal may occur between populations. While these results suggest some movements between the eastern and western populations may take place, the maintenance of genetic differences between the two populations supports their recognition as separate eastern and western populations. Future efforts should focus on elucidating the nature and extent of any dispersal which is occurring in order to better understand factors potentially influencing the recovery of the small western population.
Maakt de CEO het verschil? De impact van CEO karakteristieken op acquisitieprestaties

Acquisities zijn populair bij ondernemingen die groeistrategieen nastreven. Middels acquisities zijn ondernemingen in staat om relatief snel te groeien en over nieuw (intellectueel) kapitaal te beschikken. Echter, acquisities staan erom bekend dat zij complex en risicovol zijn, waarbij groei van aandeelhouderswaarde vaak beperkt blijft. Dit fenomeen heeft academici de afgelopen decennia in haar greep gehouden, maar voorgaand onderzoek heeft nog niet tot een volledig raamwerk van factoren geleid waarmee acquisitieprestaties kunnen worden voorspeld. Gebaseerd op de theorie van adaptief lerend vermogen, geeft deze studie inzicht hoe de achtergrond van de CEO de acquisitieprestaties van ondernemingen beinvloedt. Dit is onderzocht door te beoordelen hoe de persoonlijke karakteristieken van de CEO het effect van CEO acquisitie ervaring op acquisitieprestaties beinvloedt. Vanuit de theoretische achtergrond zijn zes hypotheses van persoonlijke karakteristieken van de CEO gevormd. Deze hypotheses zijn getest op de cumulatieve abnormale rendementen (CAR) van acquisities. Voor dit onderzoek is een dataset samengesteld van 289 acquisities die in 2016 en 2017 door de grootste 500 Amerikaanse ondernemingen zijn uitgevoerd. Resultaten tonen aan dat de karakteristieken van de CEO van invloed zijn op acquisitieprestaties van ondernemingen. Eerder onderzoek had al aangetoond dat de achtergrond van de CEO van invloed is op de winstgevendheid van ondernemingen, dit onderzoek geeft nieuw inzicht door dit verband ook op acquisities aan te tonen. Ondanks dat in de academische literatuur een positief verband tussen CEO acquisitie ervaring en acquisitieprestaties is vastgesteld, laat dit onderzoek zien dat CEO acquisitie ervaring ook een negatief effect op acquisitieprestaties kan hebben. De leeftijd en de lengte van het dienstverband zijn twee variabelen die het effect van CEO acquisitie ervaring op acquisitieprestatie positief beinvloeden. Het effect van CEO acquisitie ervaring op acquisitieprestaties wordt negatief beinvloed wanneer de CEO een man is. Dit onderzoek levert met de resultaten een bijdrage aan de academische literatuur om acquisitieprestaties beter te begrijpen en acquisitiesucces te stimuleren. Acquisities zijn complexe en risicovolle investeringen waarbij de invloed van succesfactoren per context kunnen verschillen. Dit betekent dat professionele partijen acquisities vooraf zeer zorgvuldig moeten afwegen. De resultaten van dit onderzoek zijn beperkt te generaliseren naar andere acquisities en daarom moet rekening worden gehouden met beperkingen van dit onderzoek.
Comparative Analysis of the Mitochondrial Genomes in Gastropods

In this work we presented a comparative analysis of the mitochondrial genomes in gastropods. Nucleotide and amino acids composition was calculated and a comparative Acta biol. Colomb. , Vol. 17 n.o 2, 2012 397 410 Vol17-2J_Maquetación 1 21/11/12 6:14 Página 397
Clostridium difficile and its toxins

An investigation of Clostridium difficile has shown : 1. that the organism is resistant to cresols and phenolq and may be grown from material grossly contaminated with other organisms by culture in media containing these substances; strains isolated before this method was evised are also resistant to cresols and phenol; 2. that the organism divides into four daughter cells; 3. that each strain examined has a different strain specific agglutinogen, and that the strains are otherwise antigenically complex; 4. that the sugar reactions are fairly consistent 5. that gelatin is liquefied by all available strains in three weeks; and that apart from this there is no proteolytic activity 6. that the hyaluronidase produced by all strains is antigenically uniform? and so is the lethal toxin; 7. and that the 'haemolysin' is almost certainly complex.
Resolution and pro-resolving lipid mediators in Leishmania infection

*Correspondence Email: Negarse@gmail.com Tel: +98 [21] 64112810 Fax: +98 [21] 64112810 The acute inflammatory response is the body’s natural reaction to inciting stimuli, including trauma and pathogens. Well-known pro-inflammatory metabolites take control of this reaction to recruit the leukocytes into the inflamed tissue. These cells professionally ingest and kill the invading pathogens and clear the debris of dead or injured cells. This further signals the tissue regeneration and gain of function, another active process mediated by newly uncovered anti-inflammatory metabolites that downregulate the active inflammation. These molecules and their cognate receptors are novel targets for the treatment of chronic inflammatory diseases. Although not very well understood, these mediators are suspected of supporting intracellular parasite survival (as Leishmania parasite) and are worth further investigation for innovative therapeutic interventions.
ANALISIS PENGARUH TRANSAKSI BELANJA DARI SITUS ONLINE TERHADAP KEPUASAN KONSUMEN E-COMMERCE (Studi Kasus Mahasiswa Teknik Industri yang aktif periode 2018)

Perkembangan dunia pebelanjaan pada jaman sekarang sudah semakin maju, khususnya di Indonesia tingkat kemacetan pada jalanan dan pasar yang luas yang mendorong konsumen untuk melakukan transaksi pada jual beli online. Bisnis online adalah kegiatan bisnis yang dilakukan dalam jaringan internet yang merupakan bagian dari e-business. Banyak pelaku usaha yang tertarik untuk mengembangkan bisnis online dikarenakan memiliki keunggulan dibandingkan mendirikan bisnis di dunia nyata. E-commerce merupakan bagian dari e-business, di mana cakupan e-business lebih luas, tidak hanya sekadar perniagaan tetapi mencakup juga pengkolaborasian mitra bisnis, pelayanan nasabah, lowongan pekerjaan dll. Selain teknologi jaringan www, e-commerce juga memerlukan teknologi basis data atau pangkalan data atau databases, surat elektronik (e-mail), dan bentuk teknologi non komputer yang lain seperti halnya sistem pengiriman barang, dan alat pembayaran untuk e-dagang ini. Kepercayaan pelanggan yang tinggi mengindikasikan bahwa pelanggan puas terhadap produk yang ditawarkan, dan tingginya kepuasan seta kepercayaan membuat pelanggan akan melakukan pembelian ulang , bahkan akan merekomendasikan kepada pihak lain agar bertransaksi seperti yang dilakukannya. Pelanggan yang melakukan pembelian ulang, puas dan percaya terhadap produk online, bisa dikatakan persepsinya positif. Rasa kecewa karena ketidaksesuaian barang yang diharapkan, bisa dikatakan persepsi negatif. Abstract Title: Analysis Of Transactions Of The Site Online Shopping Customer Satisfaction On E-Commerce. The development of the shopping world in the present is increasingly advanced, especially in Indonesian, the level of congestion on the streets and the broad market that encourages consumers to make transactions on online buying and selling. Online business is a business activity carried out in the internet network which is part of e-business. Many business people are interested in developing an online business because they have advantages over establishing a business in the real world. E-commerce is part of e-business, where the scope of e-business is broader, not just commerce but also includes collaborating business partners, customer service, job openings etc. In addition to www network technology, e-commerce also requires database technology or databases, electronic mail (e-mail), and other forms of non-computer technology such as shipping systems, and payment instruments for this e-commerce. High customer trust indicates that the customer is satisfied with the product offered, and the high satisfaction after trust makes the customer will make a repeat purchase, it will even recommend to other parties to transact as he does. Customers who make repeat purchases, are satisfied and believe in online products, can be said to be a positive perception. Feeling disappointed because of the expected item discrepancies, it can be said to be a negative perception.
Differential expression of genes from Penicillium purpurogenum when grown on sugar beet pulp and glucose as carbon sources

Penicillium purpurogenum is a filamentous ascomycete which grows on a variety of natural carbon sources, among them sugar beet pulp, and secretes a large variety of cellulolytic and hemicellulolytic enzymes into the culture medium. The purpose of this work was to analyse the difference in the expression of genes when those transcribed in a medium with glucose as carbon source (a highly repressive substrate) are subtracted from those expressed when it is grown on sugar beet pulp. A subtractive cDNA library was constructed by means of suppression subtractive hybridization. In all, 101 clones were selected and 80 were found to have inserts of cDNA differentially expressed in sugar beet pulp. These cDNAs were sequenced and were queried for similarities with BLAST. Sixty-two unique expressed sequence tags (ESTs) of interest were obtained. Of them, 58% are unidentified and 5% are unclassified. The remaining sequences correspond to: 18% metabolism, 5% gene/protein expression, 5% cell/organism defence, 6% cell signalling/cell communication and 3% cell division. The complete sequences of the genes and cDNAs of two of the ESTs was performed; one of them (EST 19) codes for a putative transcriptional regulator and the other (EST 182) for a putative DNA repair protein.
Genome Snapshot and Molecular Marker Development in Penstemon (Plantaginaceae)

Genome Snapshot and Molecular Marker Development in Penstemon (Plantaginaceae) Rhyan B. Dockter Department of Plant and Wildlife Sciences Master of Science Penstemon Mitchell (Plantaginaceae) is one of the largest, most diverse plant genera in North America. Their unique diversity, paired with their drought-tolerance and overall hardiness, give Penstemon a vast amount of potential in the landscaping industry—especially in the more arid western United States where they naturally thrive. In order to develop Penstemon lines for more widespread commercial and private landscaping use, we must improve our understanding of the vast genetic diversity of the genus on a molecular level. In this study we utilize genome reduction and barcoding to optimize 454-pyrosequencing in four target species of Penstemon (P. cyananthus, P. davidsonii, P. dissectus and P. fruticosus). Sequencing and assembly produced contigs representing an average of 0.5% of the Penstemon species. From the sequence, SNP information and microsatellite markers were extracted. One hundred and thirtythree interspecific microsatellite markers were discovered, of which 50 met desired primer parameters, and were of high quality with readable bands on 3% Metaphor gels. Of the microsatellite markers, 82% were polymorphic with an average heterozygosity value of 0.51. An average of one SNP in 2,890 bp per species was found within the individual species assemblies and one SNP in 97 bp were found between any two supposed homologous sequences of the four species. An average of 21.5% of the assembled contigs were associated with putative genes involved in cellular components, biological processes, and molecular functions. On average 19.7% of the assembled contigs were identified as repetitive elements of which LTRs, DNA transposons and other unclassified repeats, were discovered. Our study demonstrates the effectiveness of using the GR-RSC technique to selectively reduce the genome size to putative homologous sequence in different species of Penstemon. It has also enabled us the ability to gain greater insights into microsatellite, SNP, putative gene and repetitive element content in the Penstemon genome which provide essential tools for further genetic work including plant breeding and phylogenetics.
The Anophelinae of Africa South of the Sahara

An improved adjustable stand of the type which is vertically upwardly and downwardly adjustable, including first and second telescopable rigid tubes, said first rigid tube being mounted at one end thereof on a base, resilient means interposed between said first and second rigid tubes for releasably biasing said second rigid tube in a normally fixed position relative to said first rigid tube; and clutch means for releasing said resilient means for vertically adjusting said second rigid tube relative to said first rigid tube.
RNA interference in Histoplasma capsulatum demonstrates a role for α‐(1,3)‐glucan in virulence

Histoplasma capsulatum is a fungal pathogen that causes respiratory and systemic disease by proliferating within macrophages. While much is known about histoplasmosis, only a single virulence factor has been defined, in part because of the inefficiency of Histoplasma reverse genetics. As an alternative to allelic replacement, we have developed a telomeric plasmid‐based system for silencing gene expression in Histoplasma by RNA interference (RNAi). Episomal expression of long RNAs that form stem–loop structures triggered gene silencing. To test the effectiveness of RNAi in Histoplasma, we depleted expression of a gfp transgene as well as two endogenous genes, ADE2 and URA5, and showed significant reductions in corresponding gene function. Silencing was target gene specific, stable during macrophage infection and reversible. We used RNAi targeting AGS1 (encoding α‐(1,3)‐glucan synthase) to deplete levels of α‐(1,3)‐glucan, a cell wall polysaccharide. Loss of α‐(1,3)‐glucan by RNAi yielded phenotypes indistinguishable from an AGS1 deletion: attenuation of the ability to kill macrophages and colonize murine lungs. This demonstrates for the first time that α‐(1,3)‐glucan is an important contributor to Histoplasma virulence.
Adenosine A2B receptor effects on post-MI remodeling and cardiac fibroblast function

ADENOSINE A2B RECEPTOR EFFECTS ON POST-MI REMODELING AND CARDIAC FIBROBLAST FUNCTION by ENBO ZHAN August 2014 Advisor: Robert Lasley, Ph.D. Major: Physiology Degree: Doctor of Philosophy Adenosine A2B receptor (A2BR) appear to contribute to chronic inflammation. This receptor is highly expressed in macrophages and cardiac fibroblasts, cells which play key roles in inflammation and healing following myocardial infarction (MI). A2BR have been shown to induce collagen production and promote organ fibrosis, although the reports of A2BR role on MI are limited and conflicting. The results of cardiac fibroblast (CF) studies however suggest that non-selective A2BR stimulation inhibits collagen expression. The hypothesis of the present study was that deletion of A2BR reduces adverse remodeling in post-MI, and selective activation of A2BR increases WT murine CF collagen and pro-inflammatory cytokines production. In our in vivo studies, MI was induced by permanent coronary artery occlusion in male WT and A2BR KO mice. Hearts were harvested at 5 or 28-day post-MI for semi quantitative RTPCR assay or sectioned and stained for morphological and histological studies. In CF experments, effects of selective A2BR (BAY 60–6583, BAY) and A2AR (CGS-21680, CGS) agonists on signaling (10 min) and collagen expression (24 h) were assessed by Western blots. Adenosine receptor expression and agonist effects (24 h) on pro-inflammatory cytokine expression were analyzed with semi-quantitative real time PCR.
Morphological Variations of the Marine Diatom Genus Actinoptychus in the Coastal Waters of Korea

A study out the fine structure of the marine diatom Actinoptychus species has been carried out for taxonomical purposes during the period from January 1983 to October 1992 in the coastal waters of Korea. The present study deals with nine Actinoptychus species, A. adriaticus var. pumila, A. affinis, A. annulatus, A. maculatus, A senarius, A. simbirskianus, A. splendens A. sp.1 and A. sp.2, on the basis of the cell shapes, cell diameters, number of sectors, central hyaline zone and narrow hyaline line or zone, shape and position of the labiate process, areolar shape, and number of areolae and areolations. Among them, only the valve shape of A. annulatus was triangular, but the other six species were disc-shaped. There were variations of the number of sectors at the valve surface showing alternately raised and depressed sectors, except for A. annulatus: 6 sectors in A. senarius, A. simbirskianus, A. sp.2, 12 sectors in A. adriaticus var. pumila, 14 sectors in A. affinis and A. maculatus, 12-22 sectors in A. splendens and 12-16 sectors in A. sp. 1. There were no differences in the cell diameters of each species compared with previous reports. All species showed a central hyaline zone on the external and internal valve. There was narrow hyaline zone near the valve margin in A. adriaticus var. pumila, A. affinis, A. maculatus, A. splendens except A. senarius. A. splendens showed a hyaline line from the central area to half of the valve margin. Most of exterior areolation was irregular except for A. affinis, but that of the interior was regular.
Weed like to see less of them

nvasive alien species (IAS) are recog-nised as one of the largest threats to biological diversity and can cost bil-lions of pounds in control and eradication programmes in countries across the world – as well as causing significant environ-mental impacts. Over the past 100 years increasing world trade and the relaxation of European trade barriers has led to more and more aliens arriving on UK shores. Not all non-native species cause problems and most are beneficial – such as the ar-ray of exotic plant species which grow in the confines of our gardens, glasshouses and agricultural land. However, when an unruly species does invade, be it a plant, nematode, fungus or insect, the impact can be devastating. This is not, however, a new phenom-enon. The accidental introduction of Po-tato Blight (
Dynamics, horizontal transfer and selection of novel DNA in bacterial populations in the phytosphere of transgenic plants

Horizontal gene transfer has played an important role in the evolution of bacteria] genomes. In this review, we outline the factors influencing bacterial utilization of horizontally transferred DNA with reference to the capture of plant transgenes in the phytosphere; including soil, rhizosphere, phyllosphere and the digestive tracts of soil mesofauna invertebrates. Moreover, the release of transgenic plant DNA in the phytosphere and the transfer of bacterial genes in plant environments by natural transformation is reviewed. Some characteristics of transgenes in transplastomic plants that may increase their likelihood of horizontal gene transfer are identified. Finally, new avenues for future studies with special reference to the elucidation of possible impacts of plant transgenes on the bacterial gene pool are suggested.