Miracle-dz/UniFAR-FTUs huggingface dataset:
Accuracy of European Stock Target Prices

Equity studies are conducted by professionals, who also provide buy/hold/sell recommendations to investors. Nowadays, target prices determined by financial analysts are publicly available to investors, who may decide to use them for investment purposes. Studying the accuracy of such analysts’ forecasts is, thus, of paramount importance. Based upon empirical data on 50 of the biggest (larger capitalisation) European stocks over a 15-year period, from 2004 to 2019, and using a panel data approach, this is the first study looking at overall accuracy in European stock markets. We find that Bloomberg’s 12-month consensus target prices have no predictive power over future market prices. Our panel results are robust to company fixed effects and subperiod analysis. These results are in line with the (mostly US-based) evidence in the literature. Extending common practice, we perform a comparative accuracy analysis, comparing the accuracy of target prices with that of simple capitalisations of current prices. It turns out target prices are not better at forecasting than simple capitalisations. When considering individual regressions, accuracy is still very low, but it varies considerably across stocks. By also analysing the relationship between both measures—target prices and capitalised prices—we find evidence that, for some stocks, capitalised prices partially explain how target prices are determined.
Evaluation of a national surveillance system for mortality alerts: a mixed-methods study

Declared competing interests of authors: Paul Aylin and Alex Bottle report that the Dr Foster Unit at Imperial College London is partially funded through a research grant by Dr Foster, a commercial health-care information company (wholly owned by Telstra Health) that provides health-care analytics solutions to NHS organisations. Paul Aylin and Alex Bottle are part-funded by a grant to the unit from Telstra Health (formerly Dr Foster Intelligence) outside the submitted work. Charles Vincent reports funding from the Health Foundation for research and from Haelo (a commercial innovation and improvement science organisation) for consultancy work.
Exercise for Life: Cancer Prevention with Exercise and Lifestyle Modifications

A lthough heart disease is the number one cause of death (COD) in the United States, cancer is more feared by most Americans. This may be with good reason too. According to the Department of Health and Human Services, the incidence of cancer is increasing. In 2006, one in every four deaths in the United States was due to cancer (1). Awareness of heart disease and its causes and prevention have been in the forefront of public health since the 1960s. As a result, the percentage of deaths caused by heart disease has decreased. During the same period, the percentage of total deaths attributed to cancer has increased. If the trend continues, within the next 10 years, cancer may surpass heart disease as the leading COD (Table 1) (1). There are many different types of cancer, but all cancers are defined as uncontrolled growth and spread of abnormal cells. If the growth of these abnormal cells remains uncontrolled, the result is death. Cancers result from a combination of external and internal forces. External, or environmental, forces include tobacco, carcinogenic (or cancer-causing) chemicals, radiation, and various types of infection. Internal, or intrinsic, causes of cancer include mutations to the cellular deoxyribonucleic acid strands or the proteins controlling their replication, hormones and hormone receptors, genetic susceptibility factors, and metabolic mutations (1). The National Cancer Institute estimates that the lifetime risk of developing cancer is approximately 50% for men and 34% for women (1). In 2002, combined cancer-related deaths surpassed cerebral vascular accidents as the number two COD (5). There are 1,500 cancerrelated deaths every day. Lung cancer is the number three COD; and colon cancer, the number five COD in the United States. The rates of various cancers, like lung and breast cancers, are increasing (3). Breast cancer is the number one cause of cancer-related death for Hispanic women and the second leading cause of cancer-related deaths for White, Black, Asian, and Native American women (3). The National Institutes of Health estimated the cost of cancer in the United States in 2005 at $209.9 billion. Most of this cost is from lost work production ($17.5 billion) and premature death of a productive community ($118.4 billion). Approximately 75% of cancers are diagnosed in people older than 55 years (1). As the age of theworking public increases, the amount of productivity lost will increase. Therefore, it becomes increasingly important to prevent cancer and improve screening to facilitate earlier treatment. According to the American Cancer Society (ACS), cancers related to cigarette smoking and alcohol consumption are totally preventable. In 2006, there were 170,000 preventable tobacco-related cancer deaths. One in every three of the 564,830 cancer deaths in 2006 were due to poor Medical Report
PV Installation System: Analysis of Performance and Degradation Mechanisms

This thesis addresses degradation of crystalline silicon photovoltaic modules in Nordic climatic conditions. Quantification of the photovoltaic module degradation rate and the identification of the underlying physical factors has a vital economic and technical importance. However, photovoltaic module degradation is influenced by many factors and among the most important ones is climate. Here, the photovoltaic module degradation rate is quantified, and the underlying physical degradation pathway are identified. This is done by using two methodologies and a three-andhalf year five-min interval data comprising four parameters. The analysis involved a thorough data filtering process and uncertainty minimization techniques. Using the double diode circuit model, the degradation of circuit parameters as a function of time is determined from the operational current-voltage data. From this, the dominant degradation pathway is identified. Examining the temporal evolution of the parameters, it was possible to identify the likely physical mechanism behind the degradation and how it is linked to the Nordic climate.
Cytoplasmic sharing through apical membrane remodeling

Multiple nuclei sharing a common cytoplasm are found in diverse tissues, organisms, and diseases. Yet, multinucleation remains a poorly understood biological property. Cytoplasm sharing invariably involves plasma membrane breaches. In contrast, we discovered cytoplasm sharing without membrane breaching in highly resorptive Drosophila rectal papillae. During a six-hour developmental window, 100 individual papillar cells assemble a multinucleate cytoplasm, allowing passage of proteins of at least 27kDa throughout papillar tissue. Papillar cytoplasm sharing does not employ canonical mechanisms such as failed cytokinesis or muscle fusion pore regulators. Instead, sharing requires gap junction proteins (normally associated with transport of molecules <1kDa), which are positioned by membrane remodeling GTPases. Our work reveals a new role for apical membrane remodeling in converting a multicellular epithelium into a giant multinucleate cytoplasm. ONE SENTENCE SUMMARY Apical membrane remodeling in a resorptive Drosophila epithelium generates a shared multinuclear cytoplasm.
Archaeology of Domestic Landscapes of the Enslaved in the Caribbean

Archaeology of Domestic Landscapes of the Enslaved in the Caribbean examines the diversity of living environments that the enslaved inhabitants of the colonial Caribbean by analyzing archaeological evidence collected from a wide variety of sites across the region. Archaeological investigations of domestic architecture and artifacts illuminate the nature of household organization; fundamental changes in settlement patterns; and the manner in which power was invariably linked with the material arrangements of space among the enslaved living and working in a variety of contexts throughout the region, including plantations, fortifications, and urban centers. While research in the region has provided a considerable amount of data at the household-level, much of this work is biased towards artifact analysis, resulting in unfamiliarity with the considerations that went into constructing and inhabiting households. The chapters in this book provide detailed reconstructions of the built environments associated with slavery and account for the cultural behaviors and social arrangements that shaped these spaces. It brings together case studies of Caribbean slave settlements through historical archaeology as a means of exposing the diversity of people and practices in these various landscapes, across the British, French, Dutch, and Danish colonies in both the Greater and Lesser Antilles as well as the Bahamian archipelago.
Magnetization switching in bistable nanomagnets by picosecond pulses of surface acoustic waves

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Magnetization switching in bistable nanomagnets by picosecond pulses of surface acoustic waves Vladimir Vlasov, Alexey Lomonosov, Anton Golov, Leonid Kotov, Valentin Besse, Alexandr Alekhin, Dmitry Kuzmin, Igor Bychkov, Vasily Temnov
Prospective study of radiation related adverse events and its management in cancer patient at tertiary care teaching hospital

Radiotherapy along with chemotherapy is an important approach to cancer treatment, however radiation therapy is associated with certain adverse event which may cause significant discomfort to patient and may impact on their day to day effect. The purpose of the study was to assess radiation related adverse event in patient who are on radiation therapy and its management to provide maximum benefit to the patient with minimal side effects and to monitor the impact of adverse event in cancer patients. In all the cancers, the cells start dividing into multiple immature cells in uncontrollable way and spread into nearby tissues. In the case of cancer, the process of ABSTRACT
Association of Nonalcoholic Fatty Liver Disease with Insulin Resistance in Type 2 Diabetes Mellitus – A Prospective Study

Background: Association of Nonalcoholic fatty liver disease (NAFLD) with type 2 diabetes mellitus (T2DM) is common. Our aim was to study the association of NAFLD with Insulin Resistance in T2DM patients. Materials and Methods: Our study population included 100 patients of T2DM attending the medical out patient department of a Tertiary care center in Kochi. Presence of fatty liver in these patients was determined by abdominal sonography. Insulin Resistance was assessed by Homeostasis Model Assistant Insulin Resistance (HOMA-IR). P-value less than 0.05 was considered statistically significant. Results: The study group (n = 100) was divided into a NAFLD group (n = 45) and a non-NAFLD group (n = 55). The prevalence of NAFLD in our study was 45%. The prevalence of obesity (measured by BMI), central obesity (measured by waist circumference and waist hip ratio) was higher in NAFLD group with increased values of HbA1c and triglyceride levels. Insulin Resistance was significantly higher in NAFLD group than Non NAFLD group (P value 0.02, 0.02). Conclusion: The prevalence of NAFLD is high in patients of Type 2 DM. Presence of NAFLD among T2DM patients is significantly associated with Insulin resistance.
Endoscopy report mining for intelligent gastric cancer screening

Endoscopy is an important tool for gastric cancer screening. Due to the lack of effective decision support system for endoscopy, the detection of gastric cancer in the clinic is usually with low sensitivity. In this paper, we propose a Genetic Algorithm optimized Neural Network (GAoNN) approach for gastric cancer detection based on endoscopy reports mining. Considering the fact that gastric cancer sensitivity can significantly improve the 5‐year survival rate of patients, both the prediction accuracy and the sensitivity are employed to construct a multiobjective optimization model for enhancing the classification performance of GAoNN. In particular, we extended an effective genetic algorithm Nondominated Sorting Genetic Algorithm II (NSGA‐II) to train a neural network and reduced the complexity in training hyperparameters and improved the efficiency by substituting the computationally intensive stochastic gradient descent (SGD) algorithm in a neural network. Specifically, we designed the novel crossover and mutation operators and modified the nondominated ranking and crowding distance sorting procedures in NSGA‐II for GAoNN. Through testing on 8,546 real‐world endoscopy reports, we show that GAoNN achieves a prediction accuracy up to 83.74%, which is better than several competitors by significantly increasing sensitivity to 83.14%. GAoNN also reduces the training time by 30.94% when compared with conventional SGD‐based training, which indicates the feasibility of GAoNN in clinical practice.
Channel Measurement and Analysis for Polarimetric Wideband Outdoor Scenarios at 26 GHz: Directional vs Omni-Directional

This paper presents the measurement results and analysis for outdoor wireless propagation channels at 26 GHz over 2 GHz bandwidth for two receiver antenna polarization modes. The angular and wideband properties of directional and virtually omni-directional channels, such as angular spread, root-mean-square delay spread and coherence bandwidth, are analyzed. The results indicate that the reflections can have a significant contribution in some realistic scenarios and increase the angular and delay spreads, and reduce the coherence bandwidth of the channel. The analysis in this paper also show that using a directional transmission can result in an almost frequency-flat fading channel over the measured 2 GHz bandwidth; which consequently has a major impact on the choice of system design choices such as beamforming and transmission numerology.
More Foot, Less Fork: Unraveling the What, Why, and How of Increasing Physical Activity in Patients

Physical inactivity and sedentary behavior are modifiable risk factors to numerous chronic diseases and conditions such as obesity, depression, heart failure, and lower back pain. Integrating physical activity (PA) and exercise strategies into patient consultations for the prevention and treatment of chronic diseases is the epitome of the global health initiative, Exercise Is Medicine. Nutrition and health professionals can play an important role in this growing movement of increasing PA by documenting PA assessment, incorporating PA in patient counseling, prescribing tailored exercise prescriptions, and including resource referrals at each clinical visit. This article presents a brief background of PA, exercise, and sedentary behavior research and application strategies targeting health outcomes and illustrates why and how nutrition and health professionals play a role in Exercise Is Medicine to support increased PA in patient populations.
Comparison of the Effectiveness, the Safety, and the Pharmacokinetic of Snakebites Antivenoms: Review

Introduction: In Colombia, around 5000 cases of snakebites are reported annually, producing a clinical poisoning whose neutralization depends on heterologous immunoglobulins. Commercially, secondgeneration complete immunoglobulins and thirdgeneration fabotherapies can be found; however, their differences are unknown to many physicians. Objective: To present the main pharmacokinetic characteristics by comparing the different generations of antivenoms, as well as the frequency of side effects. Materials and Methods: A literature search was conducted in databases using a combination of descriptors and Mesh terms, in English and Spanish. Pharmacokinetic parameters were compared in preclinical studies and side effects in clinical studies. Results: From the researchers analyzed, we found that the main pharmacokinetic differences are a consequence of the size of the immunoglobulin fraction, so the fabotherapic have a greater distribution to the tissues and a shorter half-life, compared with the complete immunoglobulins. At a clinical level, studies were found that showed higher to lower presentation of side effects to complete immunoglobulins, followed by antivenoms F(ab ́)2 and Fab respectively. Conclusion: There are big pharmacological differences between the generations of antivenoms, which are exposed in this document as a practical tool to optimize the adequate pharmacological treatment in snakebite.
Bilateral teleoperation with continuously variable scaling and PD force control

This paper investigates the bilateral teleoperation with the possibility of continuously variable scaling during real-time operation. The algorithm proposed for this purpose provides the operator with the ability to change the scaling gains of force and velocity loops during operation. The controllers are derived to enforce exponentially decaying error dynamics on systems which have inner loop disturbance compensation. The proposed architecture assumes the scale factors as continuous functions of time which have continuous derivatives that are also included in the mathematical derivation. Unlike the existing studies, the presented framework allows real-time adaptation of scaling gains, which provides the user with the ability to conduct coarse and fine motion in the same operation. The Lyapunov stability proof of the proposed method is made and the margins of the controller gains are identified for practical operation. Furthermore, the operational accuracy is enhanced by the application of a PD force control loop which is also new for scaled bilateral teleoperation. The realization of PD loop is made using an α - β - γ filter to differentiate the force signal. The algorithm is validated on a setup consisted of two single DOF motion control systems. In order to provide a complete analysis, a wide range of experiments are made, velocity and force scales having sinusoidal patterns with different amplitudes and frequencies. Moreover, comparison with a classical bilateral control architecture is made to highlight the flexibility of the proposed control method. The efficacy of the proposed approach is solidified by the successful tracking responses obtained from these experiments.
A Study on the Behavior of Clustering Techniques for Modeling Travel Time in Road-Based Mass Transit Systems

In road-based mass transit systems, the travel time is a key factor affecting quality of service. For this reason, to know the behavior of this time is a relevant challenge. Clustering methods are interesting tools for knowledge modeling because these are unsupervised techniques, allowing hidden behavior patterns in large data sets to be found. In this contribution, a study on the utility of different clustering techniques to obtain behavior pattern of travel time is presented. The study analyzed three clustering techniques: K-medoid, Diana, and Hclust, studying how two key factors of these techniques (distance metric and clusters number) affect the results obtained. The study was conducted using transport activity data provided by a public transport operator.
Ofdm-mimo Receiver Performance In Underwater Miso Networks

Due to the frequency-selective nature of the underwater acoustic channel, OFDM has been proposed for use in underwater acoustic communication networks. However, because of the relatively low speed of sound in water in comparison to the speed of electromagnetic waves in air, the underwater acoustic channel is prone to a signiﬁcant amount of Doppler distortion, which OFDM is particularly sensitive to. MISO architectures have several potential applications in wireless networks, either in increasing signal diversity and thus increasing the effective SNR, or in increasing spectral efﬁciency of transmissions. However, the degradation effect due to Doppler shifting is exacerbated when a receiver detects signals from multiple transmitters which may see different Doppler distortions. In this thesis, we look at existing proposed OFDM receiver designs for use in underwater acoustic networks, and compare their performance in a MISO network composed of two transmitters and one receiver. These performance comparisons are analyzed ﬁrst through the use of MATLAB simulations and then through physical experiments in a controlled laboratory environment. Two receiver algorithms in particular are explored in detail. The ﬁrst is a block-by-block approach in which pilot tones are transmitted in every OFDM block and used to estimate the channel. The second is an adaptive receiver which uses previous channel estimates and a data-directed approach to further estimate the channel response. These two approaches achieve near equal performance, but the block-by-block receiver has a much lower spectral efﬁciency due to the overhead needed to carry the pilot tones. We thus conclude that in environments which can handle potential reductions in performance, the adaptive receiver is clearly the optimal choice. However, in fast-changing or low SNR environments, the block-by-block approach may be preferred.
Age and Ageing

Background: low vitamin B12 concentrations are common in older people, but the clinical relevance of biochemical evidence of vitamin B12 deficiency in the absence of anaemia is uncertain. Objective: to examine associations of cognitive impairment, depression and neuropathy with blood measurements of vitamin B12 and folate status in older people. Design: cross-sectional study in general practice in Banbury, England. Participants: a total of 1,000 individuals aged 75 years or older living in the community. Results: low vitamin B12 concentrations were identified in 13% of older people and were associated with memory impairment and depression. After adjustment for age, sex and smoking, individuals with vitamin B12 or holotranscobalamin (holoTC) in the bottom compared with top quartiles had a 2-fold risk (OR = 2.17; 95% CI 1.11–4.27) and a 3-fold risk (OR = 3.02; 95% CI 1.31–6.98) of cognitive impairment, respectively. Low vitamin B12 status was also associated with missing ankle tendon jerks but not with depression. Treatment with vitamin B12 for 3 months corrected the biochemical abnormalities but had no effect on any of the clinical measurements. Conclusions: low vitamin B12 concentrations are associated with cognitive impairment and missing ankle tendon jerks in older people in the absence of anaemia. Large-scale trials of vitamin B12 supplementation are required to assess the clinical significance of these associations.