The Effects of Chromium on Skeletal Muscle Membrane/Cytoskeletal Parameters and Insulin Sensitivity

S Hoffman NJ and Elmendorf JS: Mechanistic insight into the essentiality of chromium in glucose homeostasis. 2011 Keystone Symposium: Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction Hoffman NJ, Habegger KM, Elmendorf JS: (2010) Chromium protects against hyperinsulinemia-induced membrane/cytoskeletal derangements and insulin resistance in cultured skeletal muscle myotubes. Diabetes 59, Supplement 1 Hoffman NJ, Habegger KM, Elmendorf JS: (2009) Identification of an actin-based antidiabetic action of chromium in skeletal muscle. 49 Annual ASCB Meeting, Late-Breaking Abstracts On-Site Addendum PROFESSIONAL CONFERENCES ATTENDED  Indiana Life Sciences Collaboration Conference Series May 2011 Health Information Technology: Indiana’s Role in the Development of a National Model Indianapolis, IN  Indiana Life Sciences Collaboration Conference Series February 2011 Update on Regulatory Compliance Indianapolis, IN  1 Annual Indiana Physiological Society Meeting February 2011 Indianapolis, IN  2011 Keystone Symposia Conference Series January 2011 Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction Keystone, CO  70 Scientific Sessions of the American Diabetes Association June 2010 Orlando, FL  Indiana Life Sciences Collaboration Conference Series February 2010 Effective Collaboration: A Study in Three Acts Indianapolis, IN  49 Annual Meeting of the American Society for Cell Biology December 2009 San Diego, CA  Indiana Life Sciences Collaboration Conference Series November 2009 Comparative Effectiveness: The Dollars and Sense Bloomington, IN PROFESSIONAL AFFILIATIONS  Indiana Physiological Society, Student Member 2011-2012  American Association for the Advancement of Science, Student Member 2010-2012  American Society for Cell Biology, Student Member 2010-2012  Indiana University Kelley School of Business 2009-2011 Center for the Business of Life Sciences, Graduate Student Associate  American Physiological Society, Student Member 2008-2012 PRESENTATIONS  Oral Presentation August 2011 2011 Sigma Xi Biomedical Research Competition  Oral Presentation July 2011 Baker IDI Heart & Diabetes Institute Melbourne, Australia  Oral Presentation July 2011 Garvan Institute of Medical Research Sydney, Australia  Oral Presentation April 2011 Indiana University Center for Diabetes Research Seminar Series  Thesis Proposal Oral Presentation March 2011 Department of Cellular & Integrative Physiology Seminar Series  Research Poster Presentation February 2011 Indiana Biomedical Gateway Program Recruitment Poster Session  Research Poster Presentation February 2011 1 Annual Indiana Physiological Society Meeting Indianapolis, IN  Research Poster Presentation January 2011 Keystone Symposium: Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction Keystone, CO  Oral Presentation December 2010 IUPUI Center for Membrane Biosciences Meeting  Research Poster Presentation June 2010 70 Scientific Sessions of the American Diabetes Association Orlando, FL  Oral Presentation May 2010 2010 Sigma Xi Biomedical Research Competition  Research Poster Presentation April 2010 2010 IUPUI Research Day  Research Poster Presentation February 2010 Indiana Biomedical Gateway Program Recruitment Poster Session  Oral Presentation February 2010 Department of Cellular & Integrative Physiology Seminar Series  Research Poster Presentation January 2010 Indiana Biomedical Gateway Program Recruitment Poster Session  Research Poster Presentation 49 Annual Meeting of the American Society for Cell Biology December 2009 San Diego, CA  Oral Presentation October 2009 2009 Indiana Physiology Statewide Departmental Retreat  Oral Presentation August 2009 Department of Cellular & Integrative Physiology Seminar Series  Research Poster Presentation February 2009 Indiana Biomedical Gateway Program Recruitment Poster Session  Research Poster Presentation January 2009 Indiana Biomedical Gateway Program Recruitment Poster Session  Research Poster Presentation October 2008 2008 Indiana Physiology Statewide Departmental Retreat AWARDS  Co-3 Place Presentation: 2011 Sigma Xi Biomedical Research Competition 2011  IUPUI Graduate and Professional Student Government 2011 Educational Enhancement Grant  1 Annual Indiana Physiological Society Meeting Student Abstract Award 2011  IUPUI Center for Membrane Biosciences Student Travel Award 2011  2 Place Presentation: 2010 Sigma Xi Biomedical Research Competition 2010  1 Place Presentation: Center for the Business of Life Sciences Competition 2010 “Global Events and Trends Impacting the Life Sciences Industry”  Butler University Biology Departmental Honors 2003-2007  Hendricks Regional Health Scholarship 2003-2007  Butler University College of Liberal Arts and Sciences Scholarship 2003-2007  National Society of Collegiate Scholars 2004-2007 RESEARCH INTERESTS  Cellular and molecular mechanisms of insulin resistance  Glucose transporter biology and regulation  Nutritional aspects of health and disease RESEARCH EXPERTISE  Cell culture (L6 myotubes and 3T3-L1 adipocytes)  Preparation and analysis of protein: SDS-PAGE  Western blot analysis  Whole cell immunofluorescence  Subcellular fractionation  Fluorescent and confocal microscopy in cultured cells and intact tissue  Animal care and maintenance (mice and swine)  Dissection: rodent brain, heart, liver, kidney, skeletal muscle, and fat pads  Intraperitoneal glucose tolerance testing (mice)  Intraperitoneal insulin tolerance testing (mice)  Intravenous glucose tolerance testing (swine)  Blood collection (mice and swine)  2-deoxyglucose uptake assay  Amplex Red cholesterol assay  Electroporation and plasmid transfection  Luciferase and renilla assays  siRNA knockdown  Preparation and analysis of DNA and RNA: PCR, sequencing, agarose and acrylamide gel electrophoresis, plasmid isolation, restriction digest, ligation, vector construction, isolation of DNA and RNA TRAINING EXPERIENCES Indiana University School of Medicine May 2008-February 2012 Department of Cellular and Integrative Physiology Mentor: Jeffrey S. Elmendorf, Ph.D. (Associate Professor) University of Tasmania, Department of Zoology February 2006-July 2006 Butler University, Biology Department January 2005-December 2005 Undergraduate Research in Behavioral Ecology Mentor: Stephen Perrill, Ph.D. (Professor) Clarian Health Emergency Medical Education Program May 2004-August 2004 State of Indiana, Emergency Medical Technician Training Larue D. Carter Memorial Hospital April 2003-August 2003 Teaching Research Treatment Program TEACHING EXPERIENCE F782: Physiology and Pathophysiology of Lipid Rafts March 2011 Lecture to graduate students: “Bilayering GLUT4: Lipid Rafts and Insulin Resistance” Indy Parks: Holliday Park May 2007-August 2007 Youth Nature Education Programs Coordinator PROFESSIONAL AND UNIVERSITY SERVICE  IUPUI Responsible Conduct of Research Workshop 2011 Panel Member  Department of Cellular & Integrative Physiology Retreat 2011 Moderator for Graduate Student Session  American Society for Cell Biology Ambassador 2010-present  Indiana University School of Medicine 2010 Department of Cellular & Integrative Physiology 2010 Summer Seminar Series Student Coordinator  Indiana University School of Medicine 2010 Science Olympiad Volunteer  Indiana University School of Medicine Graduate Committee 2009-2011 Student Representative  Indiana University School of Medicine Second Look Program Student Panel 2009  Indiana University School of Medicine Student Mentor 2008-2011  Indiana University School of Medicine Student Ambassador 2008-2011 Student Coordinator for Campus Visits  Butler University Biology Department Student Advisory Board 2006-2007  Butler University Biology Department Student Mentor 2005-2007  Butler University Biology Club Field Trip and Social Chair 2006-2007 COMMUNITY SERVICE  Indy Parks: Holliday Park 2006-2007 Volunteer Naturalist  Wishard Memorial Hospital Pediatric Primary Care Center 2005 Founder and coordinator, Childhood Obesity Prevention Health Fair  Larue D. Carter Memorial Hospital 2003 Volunteer, Health Education Programs and Recreational Therapy