Miracle-dz/UniFAR-FTUs huggingface dataset:
Connectomic analysis reveals an interneuron with an integral role in the retinal circuit for night vision

The mammalian rod bipolar (RB) cell pathway is perhaps the best-studied circuit in the vertebrate retina. Its synaptic interactions with other retinal circuits, however, remain unresolved. Here, we combined anatomical and physiological analyses of the mouse retina to discover that the majority of synaptic inhibition to the AII amacrine cell (AC), the central neuron in the RB pathway, is provided by a single interneuron type: a multistratified, axon-bearing GABAergic AC, with dendrites in both ON and OFF synaptic layers, but with a pure ON (depolarizing) response to light. We used the nNOS-CreER mouse retina to confirm the identity of this interneuron as the wide-field NOS-1 AC. Our study demonstrates generally that novel neural circuits can be identified from targeted connectomic analyses and specifically that the NOS-1 AC mediates long-range inhibition during night vision and is a major element of the RB pathway.
The value of transperineal prostate biopsies with mMRI cognitive guidance to increase tumor detection and mean tumor volume with less number of cores.

Poster: "ECR 2014 / C-2069 / The value of transperineal prostate biopsies with mMRI cognitive guidance to increase tumor detection and mean tumor volume with less number of cores. " by: "J. Garcia-Bennett, D. Parada Dominguez, C. Hurtado Salom, E. Rebenaque, A. Conejero Olesti, J. A. Abreu de Con; Reus, SP/ES"
Multilayered Chemically Modified Electrode Based on Carbon Nanotubes Conglutinated by Polydopamine: A New Strategy for the Electrochemical Signal Enhancement for the Determination of Catechol

Abstract A new strategy was developed for the construction of a multilayered chemical modified electrode. The electrode was modified with two layers of carbon nanotubes conglutinated by polydopamine embedded with β-cyclodextrin. The practicability of the designed electrode was validated by the determination of catechol as a model molecule. Using the multilayered electrode, the redox peak currents in cyclic voltammetry for catechol were enhanced significantly compared with an electrode modified with single-layer carbon nanotubes. With the amount of added β-cyclodextrin and pH optimized, the peak currents showed good linear relationship with concentrations of catechol in the range from 2.50 × 10−7 to 4.00 × 10−3 mol·L−1 with a detection limit of 4.00 × 10−8 mol·L−1 based on a signal-to-noise ratio equal to three. The recovery values for spiked tap water and lake water were also satisfactory.
Dynamics in the Agricultural Sectors of the Baltic States: the Effects of the Common Agricultural Policy and Challenges for the Future

Sustainable agriculture is the basis for long-term economic growth ensuring employment for the rural population. The aim of this research is to assess the dynamics in agricultural output, investments, direct payments and energy use in Estonia, Latvia and Lithuania under the Common Agricultural Policy (CAP) during 2008-2017. The method of research is the evaluation of production factors generated by agriculture and related activities carried out by the model of the EAA system. The performance of the agricultural holdings is measured using economic indicators: output of the agricultural 'industry', gross fixed capital formation (GFCF), direct payments, return on capital, total labour force input, average farm income. We discuss the trends in absolute and relative indicators relates to different aspects of the sustainable agricultural development to identify the key priorities of the CAP in the Baltic States which are new European Union Member States.
Status and Physics of the SHiP experiment at CERN

SHiP is a new general purpose fixed target facility, whose Technical Proposal has been recently reviewed by the CERN SPS Committee and by the CERN Research Board. The two boards recommended that the experiment proceeds further to a Comprehensive Design phase in the context of the new CERN Working group ”Physics Beyond Colliders”, aiming at presenting a CERN strategy for the European Strategy meeting of 2019. In its initial phase, the 400 GeV proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2 × 1020 pot in 5 years. A dedicated detector, based on a long vacuum tank followed by a spectrometer and particle identification detectors, will allow probing a variety of models with light long-lived exotic particles and masses below O(10) GeV/c2. The main focus will be the physics of the so-called Hidden Portals, i.e. search for Dark Photons, Light scalars and pseudo-scalars, and Heavy Neutrinos. The sensitivity to Heavy Neutrinos will allow for the first time to probe, in the mass range between the kaon and the charm meson mass, a coupling range for which Baryogenesis and active neutrino masses could also be explained. Another dedicated detector will allow the study of neutrino cross-sections and angular distributions. ντ deep inelastic scattering cross sections will be measured with a statistics 1000 times larger than currently available, with the extraction of the F4 and F5 structure functions, never measured so far and allow for new tests of lepton non-universality with sensitivity to BSM physics.
Prevalence and Recent Trend in the Antibiogram of Staphylococcus Species Isolated from Clinical Specimens in a Rural Tertiary Care Hospital in South India

Staphylococcus is a common bacterium found in clinical samples (Diekema et al., 2001) and also found to cause human infections (Lowy, 1998). Staphylococcus aureus (S. aureus) being the most important member of this group (Javid et al., 2006) usually produces skin infections and if left untreated it may progress to a wide range of complications like wounds, tissue infections, pneumonia, joint and /or bone infections (Delorme et al., 2009). It is also the most frequently encountered species in the hospitals (Emmerson et al., 2004). The hospital acquired infections includes wound infections, ventilator associated pneumonia, blood stream infections caused by intravenous devices and prosthetic materials. The major reservoir of Staphylococcus International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 12 (2016) pp. 644-649 Journal homepage: http://www.ijcmas. com
A longitudinal investigation into the association of smoking and depression among adolescents : exposures, outcomes, and auxiliary hypotheses.

Introduction: The association between smoking and depression has been well established, but the nature of the relationship has not been determined. A synthesis of longitudinal studies examining the onset of smoking and depression among adolescents demonstrated consistent evidence of both smoking predicting depression and depression predicting smoking in multiple populations; however, more work is needed to develop and test the mechanisms associated with the onset of the co-occurrence of smoking and depression. This thesis examines the role of a broad range of potential confounders on the relationship between smoking and depression, and investigates a potential mechanism of effect. Method: Analyses were conducted using the Nicotine Dependence in Teens (NDIT) cohort which included 1293 students initially aged 12-13 years recruited from all grade seven classes in a convenience sample of ten secondary schools in Montreal, Canada surveyed twenty times over five years. Multiple regressions were performed to examine the temporal relationship of potential confounders on the relationship between smoking and depression and to empirically observe variables that could be intermediate on pathways between smoking and depression. A growth
A multiperiod model for estimating the cost of deposit insurance under the Basel III minimum capital requirement

Under the Basel III regime, a commercial bank is considered adequately capitalized if it maintains a ratio of capital to total risk‐weighted assets or capital adequacy ratio (CAR) of at least 8%. We model a commercial bank that complies with Basel III's minimum capital requirement on an interval [0,T] for T>0 . The bank model is achieved via a specific rate of capital influx that fixes the bank's CAR at the minimum prescribed level of 8%. On the basis of this capital influx rate, we derive models for the bank's asset portfolio and capital dynamics required for maintaining the CAR at the minimum prescribed level. For the aforementioned bank, we further study a deposit insurance (DI) pricing problem with a coverage horizon equal to T years. More specifically, we employ a multiperiod DI pricing model to approximate the cost of DI for the bank on the interval [0,T] , where the constant (minimum) CAR is maintained. We study the behaviours of the models leading to the constant (minimum) CAR, and the behaviour of the DI premium estimate by means of numerical simulations. In the simulation study pertaining to the DI premium estimate specifically, we determine the effects of changes in the bank's initial leverage level (deposit‐to‐asset ratio), the DI coverage horizon, and the volatility of the asset portfolio on the DI premium estimate.
Metamorphic tensegrity structure for pipe inspection

This paper proposes a new concept of metamorphic tensegrity structure for pipe inspection. A new structural deformation technique is developed that can be employed to design a non-complex and lightweight robot or vehicle. This concept is to deform the cross-shaped tensegrity structure by using the cooperation of prismatic actuators (PAs) and passive joints with locking mechanisms called restrictor mechanisms (RMs). Two control levels are designed to control the structural deformation: A high-level controller for motion patterns and low-level controllers to locally control the PA lengths and restrict the cable lengths of four RMs. Experiments show that the proposed deformation technique can deform the shape and size of the tensegrity structures with the aim of creating a new generation of pipe inspection robots.
Implications of SAFTA for Indian Economy: Trade, Compatibility and Welfare Effects

Among the members of South Asian Free Trade Area (SAFTA), India dominates in terms of its geographical location, land area, population size and economic share. However, SAFTA is treated as a weak agreement as India is highly outward oriented for trade. This raises a question about India’s trade compatibility with South Asian countries. Also since SAFTA is now fully implemented, there is a need to determine its welfare effects for India as well as for the region. The study focuses on (a) trends and patterns of India’s intra-regional trade with South Asian countries, (b) trade compatibility and (c) welfare effects of SAFTA for the Indian economy. India’s trade intensity, trade share and trade compatibility with the other regional members is calculated. GTAP simulations are used to determine welfare effects. The study is based upon the secondary data. The study finds that with the implementation of SAFTA, India’s trade intensity and trade share with its regional members has slightly improved. Trade compatibility though low, is gradually improving. The study considers SAFTA as a positive sum game for India. India is likely to have favourable allocative efficiency effect, terms of trade effect and investment-savings effect if trade facilitation measures are adopted. JEL Codes: F150, F10, F140, C150
When Twitter Becomes a Data Source for Geospatial Analysis

Social media has become a useful data source for processes and researches interested in improving people’s life. Publications done by social media users provide details about the people perceptions of their environment, and updated observations about what happens in real world. In this approach the relevance of Twitter as a data source for scientific purposes is analyzed, as well as its use in geospatial researches. Tweets have two main characteristics, a text where user describes its ideas, and metadata, where features such as the coordinates of the place where the tweet was posted are stored. Different computing procedures are applied over tweets in order to make them useful for different tasks; commonly, text mining, classification, and regression algorithms are used to process tweets. The coordinates of tweets make possible to link events described in tweets with the geographical area where they occur. The analysis of tweets and coordinates provides updated data, useful in natural disasters control, decision taking processes and urban studies. The present approach studies what motivates users to tweet, and analyzing the messages produced by Twitter users, classifies the tweets into three groups according to the information expressed in their text: self-centered, social information and collective information . Additionally, some methods to extract information from tweets are studied, common problems presented when working with tweets, and some researches that use them in a geospatial domain are presented.
UNDERSTANDING OF POLITICAL CULTURE IN CITIZEN OF MUSLIMAT NU IN EAST JAVA

In the context of its activities, since the NU Muslimat was established, it was almost all the archipelago had the same activities called religious activities, which included (1) manaqiban (2) dibaan, (3) reboan, (3) Muslimat Hajj Association and, (4) recitations with themes around the pillars of Islam. But there is a phenomenon of shifting understanding of the elite and NU Muslimat members to the themes of recitation and the movement of political da’wah, especially at the place where the research was conducted. The activities at NU Muslimat carried out not only as a routine activity of the Muslim community but also for the wider role of the NU Muslimat in general and its members to occupy strategic positions in the government or legislative members. From the above phenomena, the objectives of this study are to understand the culture and political understanding of NU Muslimat citizens in East Java. This research was conducted using a qualitative approach. Data collection uses observation, interviews, and documents. Data analysis was carried out using the Interactive Analysis Model of Miles, et al. Dalam konteks kegiatannya, sejak Muslimat NU didirikan memiliki kegiatan yang sama yang disebut kegiatan keagamaan, yang meliputi (1) manaqiban (2) dibaan, (3) reboan, (3) Ikatan Haji Muslimat , (4) kegiatan pengajian dengan tema seputar rukun Islam. Tetapi ada fenomena pergeseran pemahaman elit dan anggota Muslim NU dari kegiatan-kegiatan di atas ke tema-tema gerakan dakwah politik, terutama di tempat di mana penelitian dilakukan. Kegiatan-kegiatan Muslimat NU yang telah dilakukan tidak hanya sebagai kegiatan rutin, tetapi untuk peran yang lebih luas dari Muslimat NU pada umumnya dan anggotanya untuk menduduki posisi strategis di pemerintahan atau anggota legislatif. Dari fenomena di atas, tujuan dari penelitian ini adalah sebagai berikut: untuk memahami budaya dan pemahaman politik pada warga Muslimat NU di Jawa Timur. Penelitian ini dilakukan dengan menggunakan pendekatan kualitatif. Pengumpulan data menggunakan observasi, wawancara, dan dokumen. Analisis data dilakukan dengan menggunakan Model Analisis Interaktif Miles, Hubermen, Saldhana.
Pros and cons of radiotherapy omission in elderly breast cancer patients following breast conservative surgery

Breast cancer is a highly prevalent disease worldwide, with adjuvant radiation therapy (RT) being considered standard of care after breast-conserving surgery (BCS). Older patient population can present multiple running comorbidities and less aggressive tumor behavior, and the absolute impact of adjuvant RT on local control can be low. This article aims to review the available literature about the impact of adjuvant RT, discussing characteristics to identify lower risk cases, and advantages and disadvantages of the omission of adjuvant radiotherapy in this group.
Healthy Universities: Mapping Health-Promotion Interventions.

Purpose The purpose of this paper is to map out and characterize existing health-promotion initiatives at Florida International University (FIU) in the USA in order to inform decision makers involved in the development of a comprehensive and a long-term healthy university strategy. Design/methodology/approach This study encompasses a narrative literature review on health promotion in higher education institutions and the identification and characterization of the various health-promotion initiatives associated with the subject of healthy universities at FIU. The characterization of health-promoting initiatives relied on the stakeholder analysis approach. Using the information obtained from this study, a map for promoting health initiatives with their location, capacities, leadership, and resources was established. Findings Most publications on health-promoting universities are limited to partial experiences’ reproduction. Self-financing health-promoting initiatives foster competition and work in silos. Gains of health-promotion interventions require governance, participation, and academic considerations. This study highlights the need for standards and minimum requirements for the mapping and characterization of health-promoting initiatives within institutions of higher education. The health-promotion strategy should fall within the university’s social responsibility policy. Originality/value This study helps identify organizational strengths and weaknesses and can inform decision makers seeking to establish policies and strategies as well as defining priorities and courses of action for healthy universities.
Histological Studies of Cassava (Manihot esculenta Crantz) Root Infection Using Aspergillus niger Rhizopus stolonifer, Aspergillus niger, Aspergillus flavus, Botryodiplodia theobromae and Trichoderma viride

Histological studies were carried out to investigate the impact of some pathogenic organisms on infected cassava root after different periods of incubation. Cassava roots inoculated with Aspergillus niger, Rhizopus stolonifer, Aspergillus flavus, and Trichoderma viride showed progressive depletion of the starch grains in the cells and tissue maceration of the cassava root as the period of incubation increased. Cassava root inoculated with A. flavus showed tissue necrosis and slight fragmentation of the starch grains whereas, cassava tissues infected with A. niger showed tissue necrosis and general maceration of the starch grains within the tissue thereby creating empty spaces within the cells with no clear arrangement of the starch grains. Inoculation of the cassava tissues with R. stolonifer resulted in rapid loss of the starch grains and erosion of surrounding cell boundaries. Cassava tissue colonized by T. viride showed tissue necrosis and maceration of the starch grains. Healthy (uninoculated) cassava root tissue showed intact cells packed with large starch grains suggesting that in the host-parasite relationship, the pathogens established themselves inter and intracellularly in the parenchymatous cells of the cortex of the cassava root clearing them of starch grains, and resulting to poor yield and nutritional value of cassava and also economic loss.
Fatty-Sucrosed Diet/Minimal Dose of Streptozotocin-Treated Rat: A Novel Model of Gestational Diabetes Mellitus, Metabolic and Inflammatory Insight

To date, a variety of experiments were done to get animal models of diabetes types. The current study is a trial to get a Gestational Diabetes Mellitus (GDM) model which is comparable to that in human, using a minimal dose of Streptozotocin (STZ). Female albino rats were divided into two groups; one fed Normal Diet (ND) and the other fed Fatty-Sucrosed Diet (FSD) from 60 days of age onward. After five weeks on the diets (pregestational period), rats were mated and STZ (25 mg/kg b.wt.) was injected intraperitoneally to FSD-fed dams at the 7th day of gestation. During pregestational period, FSD-fed rats exhibited significant increase in body weight that reduced significantly after STZ injection in comparable to ND-fed rats. Frank hyperglycemia with mild decrease in serum insulin level of Gestational Diabetic (GD) dams showed a state of insulin resistance that clarified by the increase in Homeostasis Model Assessment Of Insulin Resistance (HOMA-IR) and subsequent decrease in Quantitative Insulin Sensitivity Check Index (QUICKI) values. Also, blood glycated hemoglobin (HbA1c) and fructosamine were significantly increased while hepatic glycogen content was decreased. In addition, lipid profile of GD-dams showed a significant increase in levels of Triglycerides (TG), total-cholesterol (Total-Ch.), LDL-cholesterol (LDL-Ch.) and vLDL-cholesterol (vLDLCh.) while HDL-cholesterol (HDL-Ch.) was decreased. Furthermore, serum adipokines levels showed a significant increase in leptin and tumor necrosis factor-alpha (TNF-α) while adiponectin level was significantly decreased. On the other hand, the diabetic dams exhibited high rate of implantation loss and impaired fetal glycaemia. In conclusion the combination of FSD and a minimal dose of STZ can effectively induce gestational diabetes analogue to that of human and suitable for further investigations of physiological and molecular abnormalities in GDM.
Serelaksyna — czy mamy przełom w leczeniu ostrej niewydolności serca? Wyniki badania RELAX-AHF

Ostra niewydolnośc serca (AHF) jest chorobą o bardzo zlym rokowaniu, na ktorą kazdego roku na świecie zapada ponad 15 milionow pacjentow. Mimo wielu prob klinicznych prowadzonych w ostatnich dekadach rokowanie chorych leczonych z jej powodu nie poprawilo sie, a w stosowanej farmakoterapii nie wprowadzono powazniejszych zmian. W terapii AHF wciąz brakuje leku, ktory poprawialby wyniki odlegle, nie zwiekszając przy tym w znacznym stopniu ryzyka niedokrwienia mieśnia sercowego czy groźnych arytmii. Serelaksyna, czyli rekombinowana ludzka relaksyna 2, to hormon ktorego podwyzszone wartości obserwuje sie we krwi u kobiet w ciązy. Relaksyna, aktywując sprzezony z bialkiem G receptor LGR7 (RXFP-1), prowadzi do zwiekszonej produkcji tlenku azotu przez komorki środblonka. W ten sposob dziala naczyniorozszerzająco, zmniejsza opor obwodowy, poprawia pojemnośc minutową oraz przeplyw nerkowy.W badaniu klinicznym II fazy preRELAX-AHF potwierdzono wstepną hipoteze, zgodnie z ktorą zastosowanie serelaksyny moze przynosic korzyści chorym hospitalizowanym z powodu AHF. Kontynuacje badan nad potencjalną rolą tego związku w terapii AHF stanowilo badanie RELAX-AHF. Jego wyniki wskazują, ze serelaksyna to pierwszy lek w terapii AHF, ktorego zastosowanie w początkowym okresie hospitalizacji wplywa korzystnie na wyniki odlegle. Ta przelomowa cząsteczka zmniejszala 180-dniową śmiertelnośc zarowno z przyczyn sercowo-naczyniowych, jak i ogolnych wśrod pacjentow z AHF. Serelaksyna skutecznie ograniczala takze odczuwaną dusznośc, charakteryzując sie korzystnym profilem bezpieczenstwa. W niniejszym artykule przedstawiono zalozenia, metodologie oraz wyniki prospektywnego, randomizowanego, przeprowadzonego metodą podwojnie ślepej proby badania klinicznego RELAX-AHF sluzącego porownaniu skuteczności i bezpieczenstwa stosowania serelaksyny wzgledem placebo w leczeniu pacjentow hospitalizowanych z powodu AHF.
Global Trolling: The Case of "America First"

This study examines a global trolling event, “America First,” with the intention to identify whether global trolling exists, and if so, what trolling behaviors and tactics characterize global trolling. Through an analysis of sixty videos from different countries that featured “America First” as their common theme, we were able to focus on the specific cultural manifestations of global trolling. Back in 2017, the videos were posted over a three-week period and they all exhibit repetitive, provocative, pseudo-sincere, and satirical trolling behaviors. While trolling behaviors crossed national boundaries, at times they were correlated with Hofstede’s dimensions of cultural diversity. Future research may examine the extent to which these relationships exist in other global trolling