Miracle-dz/UniFAR-FTUs huggingface dataset:
Indoor Concentration and Composition of Fine Particulate Matter (PM2.5) Near an Intense Circulated Road in an Industrial City

The purpose of the present work is to present results from a measuring campaign during February-March 2020, in Galati city, Romania, aiming the concentration of fine particulate matter (PM2.5) in air and their heavy metal concentrations, then comparing the results with the air quality determined by the national monitoring system from the same city. Results show considerable differences concerning the air quality measured in this study compared with measurements of the national monitoring system that consist in four stations placed across the city. While values recorded in this study exceeded, in some situations, the maximum target from PM2.5, the reports from the national monitoring system presented a good air quality, using a colour- and number-coding (maximum level 4 out of 6 was reported). Heavy metal concentrations of the fine particulate matters collected in this study was compared with other studies across the world, high Fe and Zn values being registered in agglomerated and industrialized cities, including the city considered in the present study, while in a study conducted in Beijing, China most higher values between all analysed heavy metals were recorded.
A Novel Deep Learning Backstepping Controller-Based Digital Twins Technology for Pitch Angle Control of Variable Speed Wind Turbine

This paper proposes a deep deterministic policy gradient (DDPG) based nonlinear integral backstepping (NIB) in combination with model free control (MFC) for pitch angle control of variable speed wind turbine. In particular, the controller has been presented as a digital twin (DT) concept, which is an increasingly growing method in a variety of applications. In DDPG-NIB-MFC, the pitch angle is considered as the control input that depends on the optimal rotor speed, which is usually derived from effective wind speed. The system stability according to the Lyapunov theory can be achieved by the recursive nature of the backstepping theory and the integral action has been used to compensate for the steady-state error. Moreover, due to the nonlinear characteristics of wind turbines, the MFC aims to handle the un-modeled system dynamics and disturbances. The DDPG algorithm with actor-critic structure has been added in the proposed control structure to efficiently and adaptively tune the controller parameters embedded in the NIB controller. Under this effort, a digital twin of a presented controller is defined as a real-time and probabilistic model which is implemented on the digital signal processor (DSP) computing device. To ensure the performance of the proposed approach and output behavior of the system, software-in-loop (SIL) and hardware-in-loop (HIL) testing procedures have been considered. From the simulation and implementation outcomes, it can be concluded that the proposed backstepping controller based DDPG is more effective, robust, and adaptive than the backstepping and proportional-integral (PI) controllers optimized by particle swarm optimization (PSO) in the presence of uncertainties and disturbances.
A 2.6‐g sound and movement tag for studying the acoustic scene and kinematics of echolocating bats

To study sensorimotor behaviour in wild animals, it is necessary to synchronously record the sensory inputs available to the animal, and its movements. To do this, we have developed a biologging device that can record the primary sensory information and the associated movements during foraging and navigating in echolocating bats. This 2.6‐g tag records the sonar calls and echoes from an ultrasonic microphone, while simultaneously sampling fine‐scale movement in three dimensions from wideband accelerometers and magnetometers. In this study, we tested the tag on an European noctula Nyctalus noctula during target approaches and on four big brown bats Eptesicus fuscus during prey interception in a flight room. We show that the tag records both the outgoing calls and echoes returning from objects at biologically relevant distances. Inertial sensor data enables the detection of behavioural events such as flying, turning, and resting. In addition, individual wing‐beats can be tracked and synchronized to the bat's sound emissions to study the coordination of different motor events. By recording the primary acoustic flow of bats concomitant with associated behaviours on a very fine time‐scale, this type of biologging method will foster a deeper understanding of how sensory inputs guide feeding behaviours in the wild.
IDENTIFICATION OF THERAPY PROFILE AND FACTORS RELATED TO INCIDENCE OF PULMONARY TUBERCULOSIS IN DENPASAR-BALI

Background: Tuberculosis is a problem for millions of people around the world. Indonesia as the second biggest country with the highest number of Pulmonary Tuberculosis that treatment has improved gradually. Denpasar is a city with the highest sufferers in Bali. It’s caused by the high rate of population, dense human settlement, and other related factors. Objective: Profiling incident and pulmonary tuberculosis treatment in Denpasar City primary health care. Methods: Observational study with cross-sectional analytic approaches. Forty pulmonary tuberculosis patients and One hundred twenty non-tuberculosis patients were observed in this study. Those were taken by multistage random sampling. Data were collected from medical records and questionnaires. A Chi-Square test was used for analyzing data. Results: Pulmonary tuberculosis sufferers are in productive ages which 65% were men. The treatment profile was excellently seen from the final treatment results of 31 people recovered and 9 people with complete treatment. Factors that have a statistical relation with pulmonary tuberculosis were occupation (p=0,012), income (p=0.003), smoking behavior (p=0.001), and contact history (p=0.001). The other factors with no relationship were education (p=0.270) and occupancy density (p=0.540). Conclusion: Pay attention to the caused factors of tuberculosis infection; society is suggested to implement a healthy lifestyle, maintain home sanitation, and environment. Keywords: Factor Related, Pulmonary, Tuberculosis, Primary Health Care, Denpasar City
International business negotiations in a regulated and incomplete information market

Regulations and government interventions often restrict competition in the market and rise cer-tain challenges in business negotiations, when competition in the market is more or less distorted. Remov-ing unnecessary restrains to competition and developing alternatives which still achieve the same policy objectives can bring substantial benefits for negotiation power of market business entities. Competition as-sessment is most effective when business negotiation entities have a clear sufficient information for com-paring options, sufficient resources for conducting an analysis, and sufficient technical skills for perform-ing the analysis. The aim of this article is to analyze in complex the unfolding theory and practice of development and implementation of business negotiating strategies in a regulated and incomplete infor-mation market, to reveal opportunities on development and implementing improvements of these strate-gies. Object of the research is the search of balance on negotiating powers in business negotiations in a regulated and incomplete information market. The scientific problem – negotiation theory lacks measures for assessment and balancing the negotiating powers between negotiation participants in a regulated and incomplete information market.
Antarctic subglacial drilling rig: Part III. Drilling auxiliaries and environmental measures

Abstract The Antarctic subglacial drilling rig (ASDR) is designed to recover 105 mm-diameter ice cores up to 1400 m depth and 41.5 mm-diameter bedrock cores up to 2 m in length. In order to ensure safe and convenient drilling, drilling auxiliaries are designed to support fieldwork and servicing. These auxiliaries are subdivided into several systems for power supply, drill tripping in the borehole, ice core and chip processing, and drill servicing and maintenance. The required equipment also includes two generators, a drilling winch with a cable, logging winch with a cable, control desk, pipe handler with a fixed clamp, chip chamber vibrator, centrifuge, emergency devices and fitting and electrical tools. Additionally, several environmental protective measures such as a new liquid-tight casing with a thermal casing shoe and a bailing device for recovering drilling fluid from the borehole were designed. Most of the auxiliaries were tested during the summer of 2018–2019 near Zhongshan Station, East Antarctica while drilling to the bedrock to a depth of 198 m.
Cloud Based Electronic Health Record Security by Using Image Encryption

Each and every one of us are sure to have been in hospital for the health maintenance. It is inappropriate for us to go to the same doctor every time, so each time we need to give our previous health status, the allergetic medicines, the blood report etc. to the doctor we meet, and it is not obvious that we may remember the name of medicines and reports. What if all these things are recorded and stored in a database that could be accessed from anywhere for the accurate medical treatment. Here it is, the paper introduces a cloud based electronic health record security by using image encryption which is a so called data base to store the health status, reports etc. This is made with an easy access technology as stored in a cloud so as to access it whenever necessary. However, it has recently notified about the hospitals keeping the patient record and providing it for further checkups which help in the analysis of the patient more precisely where as it could be accessed by those respective hospitals only. Thus, a new idea of developing these records into a cloud could make it accessible anywhere in the world when a patient is admitted. This provides an easy way to the bystander too if they are unaware of the health status and medicines used by the patient. The security issues related to the patient details are encrypted with attributes related to it.An electronic health record is provided with attribute-based encryption to provide the secure entry of the individual. The individual could be accessed to it using a unique id or mobile num.
Molecular regulation of skeletal muscle tissue formation and development

This article provides a complex overview of the different stages of myogenesis with an emphasis on the molecular, genetic and cellular bases for skeletal muscle growth. Animals with higher number of medium-sized muscle fibres produce meat of higher quality and in higher quantity. The number of muscle fibres that are created in the body is largely decided during the process of myogenesis. This review describes the main stages of embryonic skeletal myogenesis and the myogenic factors that control myogenesis in epaxial and hypaxial somites, limbs, the head and neck as well as postnatal muscle fibre growth and regeneration. An understanding of the molecular and genetic factors influencing the prenatal and postnatal growth of skeletal muscle is essential for the development of the new strategies and practical approaches to meat production.
Yazma Motivasyonu Ölçeği’nin Geliştirilmesi: Geçerlik ve Güvenirlik Çalışması

Yazma motivasyonu, ogrencilerin yazma becerilerinin gelisimini ve hayat boyu ilgi, istek, haz duyarak yazma becerilerini kullanma aliskanligi kazanmalarini desteklemektedir. Yazma motivasyonu yazma performansini artirdigi gibi bireyin oz duzenleme becerilerini desteklemektedir. Bireyin basarili bir yazma sonucuna ulasabilmesi icin coskunlukla yazma islemlerini gerceklestirmesini saglayan itici bir guctur. Bu arastirmanin amaci 9,5-14 yas (ortaokul 5, 6, 7 ve 8. sinif) ogrencilerinin yazma kaygilarini olcmek amaciyla guvenilir ve gecerli Yazma Motivasyonu Olcegi gelistirmektir. Acimlayici faktor analizi, test-tekrar test islemi, dogrulayici faktor analizi Elazig il merkezinde basit seckisiz ve kume orneklemeyle belirlenen 3 farkli orneklem uzerinden gerceklestirilmistir. Acimlayici faktor analizi sonucunda %42.52 toplam varyans degeriyle 13 maddelik tek faktorlu olcek yapisi, dogrulayici faktor analiziyle dogrulanmistir (x²=83.05, sd=61, RMSEA=.038, NFI=.97, NNFI=.99, CFI=.99, GFI=.95, AGFI=.93, SRMR=.039). Bu kapsamda olcegin genelinin ve alt boyutlarinin Cronbach’s Alpha, Spearman Brown ve Guttman SplitHalf guvenirlik degerleriyle, olcegin alt boyutlarinin yapi guvenirliklerinin ve test-tekrar test islemiyle elde edilen ic tutarlilik katsayisinin % 85’in uzerinde oldukca guvenilir oldugu tespit edilmistir. Arastirma sonucunda gecerli ve guvenilir bir Yazma Motivasyonu Olcegi’nin alana kazandirildigi ifade edilebilir.
Does the Firm Make the Difference? The Influence of Organizational Family-Friendly Arrangements on the Duration of Employment Interruptions after Childbirth

Despite the increase in dual-earner couples in Germany over recent decades, starting a family still often leads to a (re-)traditionalization of the division of labour in partnerships, with considerable gender differences in working hours and family obligations remaining. Consequently, after a child is born especially women face the challenge of reconciling career and family. Against this backdrop, a growing proportion of firms has started to create family-friendly working conditions to relieve the burden on their (female) employees. In the course of doing so, firms have also increasingly invested in organizational family-friendly arrangements in recent years. In this article, we analyse the effects of these arrangements on employees’ behaviour by using German-linked employer–employee data. We ask how specific organizational family-friendly measures affect a crucial point in women’s careers: the employment interruption after childbirth. Based on time-specific piecewise constant models, our results reveal that organizational family-friendly measures positively influence women’s return to the labour market after childbirth and thus result in benefits for both firms and employees. Furthermore, we find that the effects of the measures are determined by the structural context and are not time constant but vary according to the age of the child.
Genome-wide Expression Profiling and Pathway Analysis in Cyclic Stretched Human Trabecular Meshwork Cells

Purpose Regulation of intraocular pressure is dependent upon homeostatic responses of trabecular meshwork (TM) cells to mechanical stretch. Despite the important roles of miRNAs in regulating TM function and aqueous outflow, it remains unclear how miRNA and their target genes interact in response to physiological cyclic mechanical stretch. We aimed to identify differentially expressed miRNAs and their potential targets in human TM cells in response to cyclic mechanical stress. Methods Monolayers of TM cells from non-glaucomatous donors (n=3-6) were cultured in the presence or absence of 15% mechanical stretch, 1 cycle/s, for 6 or 24-hours using computer-controlled Flexcell Unit. We profiled the expression of 800 miRNAs using NanoString Human miRNA assays and identified differentially expressed miRNAs using the Bioconductor Limma package. We identified differentially expressed genes using Operon Human Oligo Arrays with GeneSpring software. Pathway analysis with WebGestalt identified stretch-related pathways. We used Integrative miRNA Target Finder from Ingenuity Pathway Analysis to identify potential miRNA-mRNA regulations. Results We identified 540 unique genes and 74 miRNAs with differential expression in TM cells upon cyclic mechanical stretch. Pathway analysis indicated the significant enrichment of genes involved in Wnt-signaling, receptor protein serine/threonine kinase signaling, TGF-β pathway, and response to unfolded protein. We also identified several miRNA master regulators, including miR-19b-3p and miR-93-5p, which may act as switches to control several mechano-responsive genes. Conclusions This study suggests that cyclic mechanical stress of TM cells triggers alterations in the expression of both mRNAs and miRNAs implicated in glaucoma-associated pathways.
Evaluation of Alvarado scoring system (Mandrels scoring) as a diagnostic aid in preoperative diagnosis of acute appendicitis at Nalanda Medical College and Hospital, Patna

Appendicitis today is the most common reason for emergency abdominal surgery and has a lifetime risk of 7-8%. Simple appendicitis can progress to perforation, which is associated with a much higher morbidity and mortality, and surgeons have therefore been inclined to operate when the diagnosis is probable rather than wait until it is certain. As a result of their concern about this, surgeons create for themselves ‘a surgical security zone which allows them to accept a 15-30% negative laparotomy rate with impunity’. These rates of negative appendicectomy have been considered acceptable because the morbidity associated with complicated appendicitis is significantly higher than that of non-therapeutic appendicectomy.
Review Analysis with Domain Ontology Sentiment Score Measurement System within an Online Application

: The proposed system provides a sentiment score pattern of products(textile) by calculating the sentiment score using a domain ontology sentiment score measurement method by analyzing the reviews provided by the customers. The system helps to easily analyze the reviews and provide accurate emotional polarity which can represent the emotional intensity of customers on a product. The emotional score shows the increase or decrease of demand and quality of a product and therefore it helps in decision making. As the product reviews are available widely the study on these reviews make an insight about the product that is the attitude and emotion towards it. Therefore the sentiment analysis is becoming more important. There are various tools and techniques available for sentiment analysis.
Diagnostic accuracy of the Xpert MTB/RIF assay for tuberculous pericarditis: A protocol of systematic review and meta-analysis

Background Tuberculous pericarditis (TBP) can lead to serious consequences. Early diagnosis and treatment are very important for TBP, but early diagnosis is still very challenging. This study aims to evaluate the diagnostic accuracy of Xpert MTB/RIF for TBP using meta-analysis method. Methods We will search Embase, PubMed, the Cochrane Library, China National Knowledge Infrastructure (CNKI), and the Wanfang database for researches assessing the diagnostic accuracy of Xpert MTB/RIF for TBP until April 2021. Any types of study design with full text will be selected and included. The Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool will be used to assess the risk of bias. We will use version 15.0 of the STATA software with the midas command packages to carry out meta-analyses. Results Evidence for diagnostic accuracy of Xpert MTB/RIF for TBP will be provided through the study, and this protocol will be submitted to a peer-reviewed journal for publication. Conclusion This study will provide evidence of Xpert MTB/RIF for TBP.
Analysis of factor V in zebrafish demonstrates minimal levels needed for hemostasis and risk stratifies human variants

In humans, coagulation factor V (F5) deficiency is a rare, clinically heterogeneous bleeding disorder, suggesting that genetic modifiers may contribute to disease expressivity. Complete loss of mouse F5 results in early lethality. Zebrafish possess many distinct advantages including high fecundity, optical clarity, external development, and homology with the mammalian hemostatic system, features that make it ideal for genetic studies. Our aim was to study the role of F5 in zebrafish through targeted mutagenesis, and apply the model to the study of human F5 variants. CRISPR-mediated genome editing of the zebrafish f5 locus was performed, generating mutants homozygous for a 49 base pair deletion in exon 4. Thrombus formation secondary to vascular endothelial injury was absent in f5-/- mutant embryos and larvae. Despite this severe hemostatic defect, homozygous mutants survived before succumbing to severe hemorrhage in adulthood. Human F5 variants of uncertain significance from patients with F5 deficiency were evaluated, and the causative mutations identified and stratified by their ability to restore thrombus formation in larvae. Analysis of these novel mutations demonstrates variable residual F5 function, with minimal activity being required to restore hemostasis. This in vivo evaluation may be beneficial for patients whose factor activity levels lack correlation with bleeding symptomatology. Furthermore, homozygous mutant embryos tolerate what is a severe and lethal defect in mammals, suggesting the possibility of species-specific factors enabling survival, and allowing further study not possible in the mouse. Identification of these factors or other genetic modifiers could lead to novel therapeutic modalities. Key Points F5 mutant fish embryos tolerate symptoms lethal in mammals but succumb to bleeding in adulthood Analysis of human variants demonstrate that all have some residual function and that minimal F5 activity is required to restore hemostasis
Mechanisms of action of a web-based intervention with health professional support to increase nebulizer adherence in adults with Cystic Fibrosis : a qualitative interview study

Background: Adherence to nebulizer treatments in adults with cystic fibrosis is often low. A new complex intervention to help adults with cystic fibrosis increase adherence to nebulizer treatments was tested in a pilot randomized controlled trial in two UK cystic fibrosis centers. Patients used a nebulizer with electronic monitoring capabilities that transferred data automatically to a digital platform (CFHealthHub) to monitor adherence over time, and a tailored website to display graphs of adherence data and educational and problem solving information about adherence. A trained interventionist helped patients to identify ways to increase their adherence. Objective: To explore the mechanisms of action of this complex intervention. Methods: A qualitative interview study undertaken concurrently with a pilot randomized controlled trial. 25 semi-structured interviews were conducted with three interventionists at two time points, 14 patients in the intervention arm of the trial, and five members of the multidisciplinary teams offering wider care to patients. A framework approach was used for analysis. Results: The intervention was informed by a theoretical framework of behavior change. There was evidence of the expected behavior change mechanisms of action. There was also evidence of Vassilev’s mechanisms of action associated with effective telehealth interventions for self-management support: relationships, visibility, and fit. Patients described how building a relationship with the interventionist through face-to-face visits with someone who cared about them and their progress helped them to consider ways of increasing adherence to medication. Rather than seeing the visibility of adherence data to clinicians as problematic, patients found this motivating, particularly if they received praise about progress made. The intervention was tailored to individuals but there were challenges in how the intervention fitted into some patients’ busy lives when delivered through a desktop computer. Conclusion: Mechanisms associated with effective telehealth interventions for self-management operated within this new intervention. The intervention was modified to strengthen mechanisms of action based on these findings, for example delivery through an app accessed via mobile phones, and then tested in a randomized controlled trial in 19 UK cystic fibrosis centers. Trial registration: ISRCTN13076797