Miracle-dz/UniFAR-FTUs huggingface dataset:
Self-treatment using a 0.5% podophyllotoxin cream of external genital condylomata acuminata in women. A placebo-controlled, double-blind study.

: In a double-blind, placebo-controlled study, self-treatment with a 0.5% podophyllotoxin cream was evaluated among 60 women afflicted solely with outer vulvoanal warts; 12 women received treatment with placebo cream and 48 women with active substance, administered twice daily in 3-day cycles once weekly for up to 3 weeks. Patients who were not completely cured after three cycles were classified as treatment failures. Four patients treated with podophyllotoxin cream were excluded: two were considered drop-outs, another patient was concurrently afflicted with intraanal warts, and a fourth patient refused further therapy with the cream due to the severity of local side effects occurring from the first course of therapy. Of the remaining 44 patients treated with active substance, the primary cure rates were 43%, 66%, and 91% after 1, 2, and 3 treatment cycles, respectively. Within a 3-month follow-up period, 6 (14%) patients who were originally considered cured exhibited some degree of either "recurrence" or "reoccurrence". Thus, a complete and permanent cure from podophyllotoxin cream occurred in 38 out of 44 patients (77%). Placebo lacked therapeutic influence. A slight-to-moderate tenderness, pain, burning, or all of the above in the treated areas was noted by more than 60% of the women who were treated with the podophyllotoxin cream.
A TEST OF CRITERIA FOR INTRODUCED SPECIES: THE GLOBAL INVASION BY THE ISOPOD SYNIDOTEA LAEVIDORSALIS (MIERS, 1881)

ABSTRACT Criteria for distinguishing introduced from endemic peracaridan crustaceans were used to deduce that a human-borne global invasion by the Oriental isopod Synidotea laevidorsalis (Miers, 1881) has occurred in the past 100 years. These criteria concern the ecological, evolutionary, and geographical attributes of introduced species. The criteria were used first to hypothesize that Synidotea laticauda is an introduced species in the eastern Pacific that arrived on the hulls of nineteenth-century sailing ships. This hypothesis was tested by searching for previously described conspecifics throughout the world. The search culminated in discoveries that Synidotea laticauda Benedict, 1897 of the eastern Pacific and Synidotea marplatensis (Giambiagi, 1922) of the Atlantic coast of South America are misidentified populations and thus synonymies of S. laevidorsalis. Synidotea brunnea Pires and Moreira, 1975, of central Brazil is also a probable junior synonym of S. laevidorsalis. The discovery of these synonymies was thus based upon predictive criteria rather than inductive classical, taxonomic revisions. These errors in species identifications indicate that the prevalence of marine and estuarine introductions has been underestimated and that the extent of many introductions remains poorly resolved.
The Technological Revolution, Segregation, and Populism – A Long-Term Strategic Response

Covid-19 is a threat, but it also creates opportunities for serious thought about the future. Given deep structural problems which have enabled populism to become embedded in England, there is a need to think of a longer-term transformation: not whether but how and where the state comes back in, and how relations between state, markets and planning, city-regions, innovation and universities are reconfigured. Historically, the two major populist movements in the advanced world (American in the late C19th and Germany et al in the 1930s) occurred as a consequence of massive technological changes; the movements were not primarily located in the big cities, and they involved those in previously established but now declining occupations. Populism only disappeared as those populations reduced in size and as those areas changed function or declined much further. Responding to the ICT revolution, populism in England (the subject of this paper) locates today in Rodriguez-Pose’s ‘places that don’t matter’ (PDMs), and is reinforced by the deep educational/residential segregation of contemporary society with 50% higher education participation and graduate-intensive big cities. But England seems stuck here and major ‘pathologies’ in the neo-liberal framework are responsible. These include higher education as a competitive market, the separation of cycles and growth in macroeconomic policy, and the reliance on markets with arms-length regulation and de facto absence of government from a shareholder-value maximising private sector. Policy is still short-term and largely made in Westminster despite city-regions. A long-term policy transformation is necessary to restart the ‘transmission belt’ of the ICT revolution. We need developing long-term plans based on city-regional agglomerations, into which core city networks linking knowledge-based companies, research universities and city-regional administrations are integrated; with expanding travel-to-work areas incorporating the ‘places that don’t matter’; and supported by a research-oriented economic policy.
Are pulse wave velocity and arterial stiffness markers for early pre-clinical atherosclerosis detection in resistant hypertensive patients?

Pulse wave velocity and arterial stiffness are considered gold standard for assessing sub clinical target organ damage. Endothelial dysfunction is directly proportional to development of pre-clinical atherosclerosis. These above-mentionedsurrogate markers are relatively higher in patients with uncontrolled or resistant hypertension patients. The objective was to assess if arterial stiffness and pulse wave velocity are also surrogate markers for pre-clinical atherosclerosis development in patients with resistant hypertension. A total of 160 patients with resistant hypertension from Croatia and India were included in the study. Their central blood pressure and other clinical values were assessed using non-invasive device. With the results obtained can conclude that arterial stiffness is an independent marker which is directly proportional to endothelial dysfunction and development of pre-clinical atherosclerosis.
Cell suspension cultures

1. Introduction 2. Cell suspension culture of M. truncatula cv. R 108 1 initiated from leaf and root explants 3. Long-term embryogenic cell suspension cultures of Medicago truncatula cv. Jemalong line M9-10a 4. References 5. Figures and Tables 1. Introduction Somatic embryogenesis is the process by which the somatic cells give rise to bipolar structure, which develop to whole plants without gamete fusion. It is strongly depends on the plant genotype, type and physiological state of the explants, the composition of the culture medium and the conditions of cultivation. Somatic embryogenesis in Medicago truncatula is strongly genotype-dependent. The process could be direct when the embryogenic structures develop directly from the initial explant, or indirect through a callus stage. Regeneration via direct somatic embryogenesis in liquid media for M. truncatula line R 108 1 from leaf and root explant has been established (Iantcheva et al. 2001; Iantcheva et al. 2005). These procedures based on suspension culture for regeneration of this model species offer new advantages: omit callus stage that allow shortening of the process of somatic embryogenesis and provide basis for morphological, biochemical and molecular studies of the nature of somatic embryogenesis from single cell to whole plant.
Role of a viral membrane polypeptide in strand-specific initiation of poliovirus RNA synthesis

A molecular genetic analysis has been combined with an in vitro biochemical approach to define the functional interactions required for nucleotidyl protein formation during poliovirus RNA synthesis. A site-directed lesion into the hydrophobic domain of a viral membrane protein produced a mutant virus that is defective in RNA synthesis at 39 degrees C. The phenotypic expression of this lesion affects initiation of RNA synthesis, in vitro uridylylation of the genome-linked protein (VPg), and the in vivo synthesis of plus-strand viral RNAs. Our results support a model that employs a viral membrane protein as carrier for VPg in the initiation of plus-strand RNA synthesis. Our data also suggest that a separate mechanism could be used in the initiation of minus-strand RNA synthesis, thereby providing a means for strand-specific regulation of picornavirus RNA replication.
Abundance and productivity of forest songbirds in a managed, unfragmented landscape in Vermont

Effective conservation of forest songbirds requires knowledge of responses to landscape pattern. We studied a breeding songbird community in a landscape characterized by scattered openings in a forest matrix in Vermont, 1993-94. We measured species composition abundance, and fledgling brood density in the forested areas of 10 500-ha sites: we compared a group of 5 disturbed-canopy sites (≤10% canopy disturbance) with a control group of 5 undisturbed-canopy sites. We conducted 456 point counts to determine species composition and abundance, and we conducted 60 line transect surveys to estimate fledgling brood density as a measure of productivity. Adult densities were not different between groups (P > 0.05) for 18 species listed as priority for conservation, although power was low. Combined brood densities of all species, Neotropical migrants, and ground nesters were not different among groups (P > 0.05). Brood densities of 3 Neotropical migrants alsa were not different (P > 0.05) However, combined brood density of area-sensitive, forest interior species was greater on control sites (P < 0.05). At the scale of this study, a minimal amount of canopy removal in the extensively forested landscap did not affect abundance and overall productivity of songbirds inhabiting the remaining forest, but canopy removal had begun to suppress productivity of some forest interior species.
Computational Topology Project Topological Encoding of Paths in the Task Space

We are interested in designing brain-machine interfaces. These interfaces are controlled by a human user through a noisy and low-bandwidth neural sensor which measures brain activity. Our particular interest is to enable users of these interfaces to control a robotics system (e.g. a wheelchair). Our recent work demonstrated that we can learn an approximate of the user’s intended path (2-dimensional path in the obstaclefree plane) by using binary inputs obtained from an electroencephalography (EEG) sensor. In EEG-based brain-machine interfaces, the input is usually one or two bits (with noise) at a rate of about one second. Because of this limitation, it takes quite a long time to specify a path. Instead of specifying the path itself with this limited input source, we can consider specifying the type of it and let the system figure out a good representative path for that type. In the context of this paper, the type of a path may correspond to different things. For example, we can consider the homotopy class of a path as its type.
AUTONOMY, BELONGINGNESS AND COMPETENCE: THE ABCs OF EMERGENCY VOLUNTEER RETENTION

CONTEXT Australian emergency services agencies have expressed a need to improve volunteer retention, which remains a significant challenge. While previous research has investigated various predictors of turnover, it did not consider the individual psychological needs of volunteers. This research investigated the needs satisfaction of volunteers and how it affects their role satisfaction, wellbeing and intentions to remain with the service. ABOUT THIS PROJECT This research began in 2017 and was conducted as part of the Enabling sustainable emergency volunteering project. This component of the project investigated issues of recruitment, retention, diversity and wellbeing among State Emergency Service volunteers, and is part of a larger study on volunteering conducted by the Bushfire and Natural Hazards CRC.
Stalkborer Damage on Yield and Quality of Sugarcane in Lower Rio Grande Valley of Texas

In the Lower Rio Grande Valley of Texas, the pyralid stalkborers Eoreuma loftini (Dyar) and Diatraea saccharalis (F.) damage ≈20% of sugarcane internodes annually. We quantified the relationships between stalkborer damage and sugar yield and quality to estimate the monetary loss incurred at these levels of damage. We also compared damage estimates and sugar quality between 2 important varieties in the region, ‘NCo 310’ and ‘CP 70–321’. NCo 310 showed greater mean percentages of bored internodes (19.4%) than CP 70–321 (10.9%). Sugar per ton also was greater in CP 70–321 (215.97 lb/t or 108 g/kg) than in NCo 310 (190.92 lb/t or 95.5 g/kg); as were juice purity and mean sucrose content. Other variables (sugar per acre, cane per acre, fiber, ash, and stalk weight) did not differ significantly between the 2 varieties. Sugar per acre, juice purity, stalk weight, cane per acre, sucrose per ton of sugarcane, and sucrose content all were inversely related to percentage of bored internodes. Ash content increased with damage, consistent with a plant displaying symptoms of stress. Regression slopes for CP 70–321 were steeper than for NCo 310, perhaps suggesting that although CP 70–321 usually displays less damage, yield and quality may be affected more severely in the event of borer damage because of its higher sugar content. In Texas, the share agreements between farmers and the sugar mill mandate that the mill retains 40% of proceeds as compensation for milling, with economic losses also shared in the same ratio. Assuming the value of raw sugar is $420/t (907.18 kg), 20% bored internodes results in a loss of $1,181.04/ha ($477.96/acre). For average Texas sugarcane acreage of 18,200 ha (45,000 acres), total losses would be $21.5 M ($12.9 M to the producers and $8.6 M to the mill). The ineffectiveness of insecticides and their abandonment by Texas sugarcane growers make it imperative that pest management alternatives, such as resistant varieties and biological control agents, be investigated to alleviate the losses.
Febrile Urinary Tract Infection after Radical Cystectomy with Urinary Diversion: Different Characteristics in Patients with Ileal Conduit and Orthotopic Neobladder

Background and Objective To compare the incidence of febrile urinary tract infection (UTI) and bacterial identification between patients with orthotopic neobladder (ONB) and ileal conduit (IC). Materials and Methods Data of 164 patients who underwent radical cystectomy with ONB and IC for bladder cancer between January 2009 and January 2018 at our institution were analyzed. Febrile UTI observed was listed and subsequently compared. Incidence of febrile UTI, clinicopathological characteristics, and microorganisms identified were reported at 3 months interval; and preoperative predictors of febrile UTI were evaluated with Cox regression analysis. Patients were divided into ONB and IC. Results The study cohort included 52 patients with ONB and 112 patients with IC. Febrile UTI was diagnosed in 49 (29.9%) patients. Compared to IC group, ONB group had significantly higher incidence of young age (p=0.00), lower cancer stage (p=0.013), longer hospital stay (p=0.049), longer operation time (p=0.00), and higher incidence of febrile UTI within the first 3 months after surgery (p=0.006). On univariable and multivariable analysis, factors associated with significantly increased febrile UTI risk were diabetes (odds ratio [OR]: 4.52; p=0.002) and ONB diversion (OR: 1.27; p=0.031). Forty-four (89.8%) patients were culture positive. However, significant difference in microorganisms was not detected between patients who underwent ONB or IC diversion. Febrile urinary tract infection after radical cystectomy e39 J Mens Health Vol 16(3):e38–e46; August 27, 2020 This article is distributed under the terms of the Creative Commons Attribution-Non Commercial 4.0 International License. ©2020 Seungsoo Lee et al. Conclusion Diabetes and ONB diversion were associated with higher risk symptomatic UTI following radical cystectomy.
Al-Sulaifanie : Finite element analysis of shear transfer of fibrous concrete under .... 1 FINITE ELEMENT ANALYSIS OF SHEAR TRANSFER OF FIBROUS CONCRETE UNDER COMPRESSIVE STRESS

This study presents a numerical analysis of push-off and modified push-off fibrous concrete specimens. The investigated variables were, volume fraction of fibres, area of reinforcement, and the ratio of the compressive to the shear stress. Eight nodes isoparametric elements were used to represent concrete, and embedded bar elements to represent the reinforcement. The nonlinear behaviour of fibrous concrete in compression, tension and the reduction of the shear modulus due to cracking were taken into account. The numerical results showed good agreement with the experimental results, the average ratio of the calculated to the experimental first crack shear stress is (0.955), and the average ratio of the calculated to the experimental shear strength was (0.981). The cracks patterns showed that the fibrous specimens have less numbers of cracks than that of plain specimens at a certain shear force, and the presence of fibres delay the initiation the cracks. The calculated slip is slightly more than the experimental slip at early stage of loading and the difference increased prior to the failure load.
Study on adptation measures taken by the farmers in response to disaster in Bajua union of Dacope upazila of Khulna district in Bangladesh

The study was conducted to determine the extent of the farmer’s perception and adaptation measures to disaster in the selected area of Bajua union of Dacope Upazila of Khulna District during March to May, 2016. The study consisted of 120 randomly selected farmers through an interview using questionnaire in order to identify the respondent's perception and their adaptation measures against disaster. The findings of the study indicated that cyclone, salinity, flood and drought were the major problems of natural disaster faced by the farmers in the study area. The result also indicated that majority (50%) of the farmers had medium impact of disaster while 47.5 % had high impact of disaster and 2.5 % respondents had low impact of disaster. However majority (59.16%) of the farmers had medium adaptation capability compare to 26.66% farmers had low and 14.16% farmers had high disaster adaptation capability. Correlation analysis of the variables indicates that there was no significant relationship of age and credit received with their adaptation measures, but the other characteristics of the farmers like, farm size, annual income, knowledge about disaster and climate, environmental hazards and impact of disaster as observed by farmers had positive significant (0.01 level) relationship with their adaptation measures. Therefore, disaster had created a great impact on farmers and in response they are taking adaptation measures which need to be accelerated in the study area.
Abstract. In order to investigate novel biomarkers for the detection of coronary artery disease for effective thera- peutic targets, a comprehensive understanding of the protein networks and protein expression abundance in coronary artery

In order to investigate novel biomarkers for the detection of coronary artery disease for effective therapeutic targets, a comprehensive understanding of the protein networks and protein expression abundance in coronary artery samples is required. This was established by means of liquid chromatography (Lc)-mass spectrometry (MS)/MS analysis in the present study. A total of 20 human coronary artery specimens from 2 autopsied adults were employed in the present study. The natural history and histological classification of the atherosclerotic lesions of the coronary artery samples were analyzed by hematoxylin and eosin (H&E) staining, and the human coronary arterial proteome and proteomics features were characterized by MS analysis. The present study identified 2,135 proteins in the 20 coronary artery segments samples from the 2 cases. combined with the results of H&E staining of the coronary artery samples, a total of 174 proteins, including 4 upregulated proteins and 164 downregulated proteins (excluding 6 proteins with inconsistent expression tendencies), were shown to be associated with coronary artery disease. In addition, Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment of the differentially expressed proteins revealed that the mitochondrial energy metabolism may be responsible for the occurrence and development of coronary artery atherosclerosis. The human coronary arterial proteome can be considered as a complex network whose architectural characteristics vary considerably as a function of the presence or absence, and histological classification of coronary artery atherosclerosis. These data thus suggest that the prevention of mitochondrial dysfunction via the retrieval of the mitochondrial associated proteins expression may be a promising target in coronary artery disease.
Optimal Policy for Investment in Human Capital in the Light of Optimal Tax Theory

The increasing amount of student loan is becoming a pressing issue for the US economy, as it exceeds 1.4 trillion dollars (or 7.2% of GDP), thus requiring a policy change. This paper presents economic literature on optimal taxation with human capital, which provides foundations for evaluating the long-run effects of taxation and endogenous investment in skills. I review insights from the dynamic models. The literature in the field considers two instruments: turning repayments income-contingent and providing subsidies to education costs. I summarize the results from theoretical and simulation studies. Income-contingent repayment schemes can improve welfare, whereas the effects of education subsidies may be positive only under some assumptions.
Critical mutation rates in small populations

Mutation introduces change at the sequence level. There is a critical mutation rate above which changes occur too frequently for natural selection to maintain the population's genetic makeup. This thesis examines the relationship between this critical mutation rate and the number of individuals in the adapting population. It presents an algorithmic method capable of providing widely applicable results in haploid and diploid populations, and veri es this method against analytical models for the error threshold. Use of the method led to the discovery of an exponential relationship between the critical mutation rate and population size, particularly strong in small populations with 100 individuals or less, contradicting the existing idea that critical mutation rate and population size are independent [1]. The critical mutation rate (and error threshold) were found to be lower in diploids due to di erences in recombination. Analysis of the survival-of-thettest to survival-of-theattest transition enabled improvement of existing de nitions of the critical mutation rate. Development of a faster algorithm capable of running experiments with parameter values within the range found in nature began the process of bridging the gap between arti cial and biological evolution. A link was established between the exponential model and natural mutation rates. Increasing the gene length by a factor of 10 was found to decrease both the critical mutation rate and error threshold by an order of
Analysis of morphometric and meristic characteristics of Pomadasys stridens (Forsskål, 1775), Family: Haemulidae from the Gulf of Suez, Red Sea, Egypt.

Morphological characteristics are of fundamental importance in fishery biology, where it is the major source of information for taxonomic and evolutionary studies. Taxonomic identification is the initial step in the study of a species. For estimating the similarities and dissimilarities among the taxonomic categories, many workers had used protein studies and DNA sequences, but this is practically not easy especially due to the expenses. The description of morphological characters are considered the easiest and authentic method of fish identification which is termed as morphological systematic. These characters are most generally divided into two major categories; the morphometric ARTICLE INFO ABSTRACT Article History: Received: Aug. 28, 2020 Accepted: Sept. 9, 2020 Online: Sept. 12, 2020 _______________