Miracle-dz/UniFAR-FTUs huggingface dataset:
COMPARISON OF LEFT VENTRICULAR EJECTION FRACTION BY SINGLE PHOTON COMPUTED TOMOGRAPHIC MYOCARDIAL PERFUSION IMAGING VERSUS CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY

Introduction: Measurement of left ventricular (LV) ejection fraction by coronary computed tomography angiography (CTA) vs. single photon computed tomographic myocardial perfusion imaging (MPI) needs to be investigated. Material and methods: Myocardial perfusion imaging and CTA were performed in 292 patients because of chest pain or dyspnea. The patients included 178 men and 114 women, mean age 66 ±11 years. Results: The mean LV ejection fraction was 61 ±12% for the MPI tests and 65 ±11% for CTA (p <0.001). The LV ejection fraction was ≥ 50% in 250 of 292 patients (86%) with MPI testing and in 266 of 292 patients (91%) with CTA (p < 0.05). The LV ejection fraction was 36-49% in 31 of 292 patients (11%) with MPI testing and in 22 of 292 patients (8%) with CTA (p not significant). The LV ejection fraction was ≤ 35% in 11 of 292 patients (4%) with MPI testing and in 4 of 292 patients (1%) with CTA (p not significant). Pearson correlation coefficient was R = 0.67, p < 0.001. Conclusions: The resting LV ejection fraction is significantly higher in patients measured by CTA than in patients measured by MPI testing when both tests are performed in the same patients.
A Survey on Haemo-protozoan parasites in buffaloes of Landhi Dairy Colony, Karachi-Pakistan.

The Landhi Dairy Colony is located in the suburbs of Karachi. It has a dairy animals population of about 400,000 (around 95% buffaloes and 5% cows, as well as an unknown number of sheep and goats), with a daily yield of about four million litres of milk and 7,200 tones of dung making it world\'s largest dairy colony. The study was conducted to record the prevalence of haemo-protozoan in buffaloes of Landhi Dairy Colony Karachi. The results of present study revealed that out of 100 samples 14 were detected positive and the overall prevalence was recorded as 14%. The incidence of bloodparasites was higher in females (15%) than male (10%). The highest percentage of infection recorded was that of Anaplasma marginale (64.28%) followed by Babesia bovis (21.42 %) and Theleria (14.285%)
Development and implementation of a dual diagnosis strategy for older people in south east London

Purpose – The provision of a seamless service to address the needs of older people with substance misuse is now more pressing than ever, particularly given the impact of a growing population of older people in society, and with co‐morbid mental health and substance use issues. There is growing recognition of the public health needs of older people with mental health problems and substance misuse. This paper seeks to consider the development and implementation of one particular dual diagnosis strategy.Design/methodology/approach – The paper examines the background, development and implementation of a dual diagnosis strategy designed to address the growing problem of substance misuse of older people in an inner city area in London, UK.Findings – A needs assessment highlighted workforce training needs which led to the commissioning of innovative training to address this. Pathways were created to allow seamless transition between services, thus enabling older adults with dual diagnosis to receive the care tha.
High Failure Rates of Melarsoprol for Sleeping Sickness, Democratic Republic of Congo

A retrospective chart review of 4,925 human African trypanosomiasis patients treated with melarsoprol in 2001–2003 in Equateur Nord Province of the Democratic Republic of Congo showed a treatment failure rate of 19.5%. This rate increased over the 3 years. Relapse rates were highest in the central part of the province.
Symptom Clusters and Functional Status of Women with Breast Cancer

บทคดยอ การวจยนมวตถประสงคเพอศกษากลมอาการ และอทธพลของกลมอาการตอความสามารถ ในการทำกจกรรมของผปวยเปนมะเรงเตานม กลมตวอยางจำนวน 320 คนเปนหญงไทยทปวยเปนมะเรงเตานมและอยในระหวางการรกษาดวยยาเคมบำบด คดเลอกโดยการสมแบบเจาะจง วเคราะหขอมลโดยใชสถตการวเคราะหปจจย และการวเคราะหความถดถอยเชงพห ผลการวเคราะหพบวากลมอาการของความรนแรงและกลมอาการของความทกขทรมานมความแตกตางกน ในการวเคราะหจดกลม สามารถจำแนกกลมอาการดานความรนแรงออกเปน 4 กลม อธบายความแปรปรวนของอาการทงหมดไดรอยละ 50.1 คอกลมอาการทางอารมณ กลมอาการดานทางเดนอาหารและอาการออนลา กลมอาการดานภาพลกษณและการเปลยนแปลงผวหนง และกลมอาการดานความเจบปวดและความไมสขสบาย ทง 4 กลมอาการมอทธพลอยางมนยสำคญทางสถต (p<0.05) คดเปนรอยละ 19.8 ของความแปรปรวนทงหมดของความสามารถในการทำกจกรรม กลมอาการดานความทกขทรมานจำแนกออกเปน 3 กลม อธบายความแปรปรวนของอาการทงหมดไดรอยละ 50.7 คอกลมอาการดานอารมณและความเจบปวด กลมอาการดานทางเดนอาหารและอาการออนลา กลมอาการดานภาพลกษณและการเปลยนแปลงผวหนง ทง 3 กลมอาการมอทธพลอยางมนยสำคญทางสถต (p<0.05) คดเปนรอยละ 17.4 ของความแปรปรวนทงหมดของความสามารถในการ ทำกจกรรม กลมอาการทางเดนอาหารและอาการออนลา เปนกลมอาการทมอทธพลตอความสามารถ ในการทำกจกรรมมากทสดทงในดานความรนแรงของอาการและความทกขทรมานจากอาการ คำ สำ คญ : มะเรงเตานม เคมบำบด การวเคราะหปจจย ความสามารถในการทำกจกรรม กลมอาการ Abstract This study aimed to explore symptom clusters across two symptom dimensions and their influences on functional status of women with breast cancer. Sample consisted of 320 Thai women diagnosed with breast cancer undergoing chemotherapy. They were purposively selected and evaluated for their symptom experiences and functional status. Factor analysis and multiple regression were used to examine symptom clusters and their significant effects on the functional status of the women. Symptom clusters existed across the two symptom dimensions. Symptom clusters of symptom severity and those of symptom distress were not identical. Four symptom clusters existed in the dimension of symptom severity, with 50.1% variance explained in all the symptoms. The clusters were emotions related symptoms, GI and fatigue related symptoms, image related cutaneous symptoms, and pain related discomfort symptoms. The clusters significantly explained 19.8% of the variance in the functional status (p<0.05). Three symptom clusters were identified in the dimension of symptom distress, with 50.7% variance in all the symptoms. They were the clusters of emotions and pain related discomfort symptoms, GI and fatigue related symptoms, and image related cutaneous symptoms. The clusters significantly explained about 17.4% of variance in the functional status (p<0.05). GI and fatigue related symptom cluster was the strongest predictor cluster affecting the functional status in both dimensions of symptom severity and symptom distress. Keywords: breast cancer, chemotherapy, factor analysis, functional status, symptom clusters
An Overview of Obesity and Weight Loss Surgery

IN BRIEF Obesity has become an epidemic in the United States, with more than 60% of the population now either overweight or obese. Lifestyle modifications and weight loss medications have failed to provide significant, lasting weight loss in the majority of people who are overweight. Weight loss surgery has proven to be a safe and effective means of losing significant and lasting weight and should be considered in those who are morbidly obese.
Pain Management Following Abdominal Hysterectomy: Novel Approaches and Review of the Literature

Abdominal hysterectomy (AH) is one of the most common surgeries performed for malignant as well as benign indications. Effective pain management depends on the cooperation between the surgeons, anesthetists and the hospital’s pain management service, and is a combination of preemptive analgesia, general and regional anesthesia, peripheral blocks and multimodal postoperative pain treatment. The objective of this work is to present the currently available therapeutic strategies for the treatment of posthysterectomy pain in the light of our experience and the literature review. doi: http://dx.doi. org/10.4021/jcgo130w
Pronóstico de recuperación funcional en personas supervivientes de un ictus

The functional prognosis of a person who has suffered brain stroke forms the basis on which the patient's and his or her family's questions can be answered, by which the rehabilitation objectives can be identified and by which the patient's problems and future needs can be assessed, in order to anticipate a solution or compensation. Defining groups of patients with homogeneous prognoses is useful both for clinical investigation and to define the casuistry of the health care services. It is necessary to establish functional prognoses on the basis of the existing evidence which are better then the informal opinion based on individual clinical experience. The recovery period of time is clearly related with the initial seriousness of the stroke: the more serious, the less and the slower the recovery. Beyond the fifth-sixth month after the stroke, even in patients with serious and very serious stroke, it is difficult to observe a higher degree of recovery with the standard scales that assess the activities of the basic daily life. A prognosis of incapacity in the middle and long term can be estimated with a 60%-80% accuracy between the first and second week after the stroke. In spite of some inconsistencies in the literature, it seems to be clear that simple variables in relationship with clinical seriousness of presentation of stroke have a higher predictive power than the etiopathogenic factors or the determination of the lesion size with neuroimaging techniques. However, there is always a certain degree of uncertainty when making an early prognosis for an individual patient, so that the patient's evolution must be followed-up in order to verify, or if such is the case, reconsider, the initial prognosis.
PROLONGED BREAST FEEDING AS PROPHYLAXIS FOR RECURRENT OTITIS MEDIA

ABSTRACT. The incidence of otitis media was studied in 237 healthy children in reference to the duration of breast‐feeding, with a follow‐up from birth to three years of age. Recurrent otitis media was strongly associated with early bottle‐feeding, in contrast to prolonged breast‐feeding which had a long‐term protecting effect up to three years of age. It is uncertain whether the prophylactic effect of prolonged breast‐feeding on recurrent otitis is due to protection by human milk from infections or allergy, or to avoidance of harmful effects caused by cow's milk.
Update on the Prevention and Treatment of Ovarian Cancer

Ovarian cancer is the fourth leading cause of cancer among women and the number one gynecologic fatality. The etiology of ovarian cancer is still an enigma. Three common hypotheses under investigation include the ovulation, the pituitary gonadotropin, and the chronic inflammatory processes. Chemoprevention strategies used for ovarian cancer include oral contraceptives, aspirin and nonsteroidal anti-inflammatory agents, and retinoids. Surgical strategies are also used in the prevention of ovarian cancer. The primary treatment for patients with ovarian cancer is surgery with optimal tumor debulking, and for patients with advanced disease, this is followed by adjuvant chemotherapy. The standard practice is to follow surgery with six cycles of paclitaxel plus carboplatin. The second-line chemotherapy agents have had minimal long-term benefit for treating ovarian cancer. Hence, treatment with investigational agents remains the best option for patients with recurrent disease due to lack of alternative curative treatment.
Medical Treatment of JJ Stent-related Symptoms

Copyright: © 2014 Dellis A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Although ureteric JJ stents have been widely used in Urology for many decades and their placement is considered a routine procedure, they are associated with significant morbidity and a negative impact on patient’s quality of life [1]. Furthermore there is no consensus regarding stent placement after ureteroscopic stone removal or whether it is needed before Extracorporeal Shock Wave Lithotripsy (ESWL) [2]. Joshi et al. recognized patient morbidity associated with ureteral JJ stents as a significant health problem and developed a validated questionnaire (USSQ: Ureteric Symptom Score Questionnaire) [3]. USSQ has been used to determine whether novel stent designs, shapes, material or drug coatings confer any improvement in JJ stent related symptoms and/or if medications decrease JJ stent related morbidity. However, despite ongoing research, the ideal ureteric stent has yet to be discovered.
Primary Care Partnerships: more than just one relationship

Victorian Primary Care Partnerships are complex. They occur within a multilayered institutional environment. They are not a simple singular relationship but rather manifest diverse forms that are consistent with a collaboration continuum across multilevel structures. Their function, process and structure differentiate these forms. This paper articulates a conceptualisation of partnership complexity that integrates these elements and interrelationships.
Anaesthesia for kidney transplantation

In 1954, Joseph Murray performed the first successful renal transplantation on identical twins. Due to improvements in immunosuppressant medication and surgical techniques in the past decades, the organ survival rate has increased significantly. A study comparing kidney recipients, patients on the waiting list and patients on dialysis showed a significant reduction in mortality in the patients that have been transplanted.1 The kidney donor pool has been expanded and even marginal organs are being transplanted, as they provide survival benefit in comparison to dialysis.2,3 The indication for renal transplantation was extended to older patients with worse medical prognosis than before.4 Particularly the recipients in the Eurotransplant Senior Program “old-for-old” require an individualised intra- and postoperative management by the attending anaesthetist.5
CHOIX DU BILAN D'EXTENSION DANS LE MASTOCYTOME CUTANE CANIN : ETUDE RETROSPECTIVE

Canine cutaneous mast cell tumor has an unpredictable biologic behaviour, ranging from a benign tumor to a malignant tumor with high risk of metastases. Its staging needs numerous analyses, but the relevance of the systematic realization of all these has been little documented. The aim of this study was to carry out first, a bibliographic review about the staging, the prognosis and the clinical management of this tumor, and then to perform a retrospective study about the choice of the staging, carried out with 48 cases of cutaneous mast cell tumors. The results of this study show that the staging can be carried out in two steps, first by analysing loco-regional lymph node. When the latter is not infiltrated, the other analyses of the staging are negative in all the cases. So there is little relevance to propose a complete staging.
Head trauma and epilepsy

Posttraumatic epilepsy (PTE) is defined as a recurrent seizure disorder due to injury to the brain following head trauma. Traumatic brain injury (TBI) accounts for 20% of symptomatic epilepsy in the general population and 5% of all epilepsy. Prevention or suppression of the development of PTE is a major unmet challenge in medicine. For an expanded treatment of this topic see Jasper’s Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado‐Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at http://www.ncbi.nlm.nih.gov/books).
Deep vein thrombosis in major trauma

Major trauma patients are at increased risk of developing deep vein thrombosis (DVT). Certain injuries may be associated with an increased DVT risk, though definitive evidence regarding specific risk factors is lacking. The role of mechanical thromboprophylaxis in major trauma remains unclear and these methods are often contraindicated in lower limb injuries. Low molecular weight heparin is effective in reducing DVT frequency in major trauma with acceptable haemorrhagic complications. Evidence regarding the efficacy of thromboprophylaxis specifically in major trauma patients is lacking. However, recently published guidelines from the National Institute for Health and Clinical Excellence appear to make recommendations based on findings in other patient populations rather than using the best available evidence in major trauma patients. Future studies must identify specific DVT risk factors in major trauma to allow accurate risk stratification, determine the time period patients remain at increased DVT risk and establish the role of combined thromboprophylaxis.
Avaliação da extensão da neoplasia em câncer da próstata: valor do PSA, da percentagem de fragmentos positivos e da escala de Gleason

OBJECTIVE: To valuate the behavior of the prostatic biopsy fragments percentage, guided by transrectal ultrasonography in extraprostatic disease prediction in patients with localized adenocarcinoma of the prostate gland and, also, to compare the efficiency of this pattern with them got by the valuation of PSA and preoperative Gleason score. METHODS: This retrospective non-controlled study consisted of 522 patients with adenocarcinoma located in the prostate. They were submitted to surgical treatment through retropubic radical prostatectomy. The ages of the patients ranged from 42 to 76 years with a mean of 62.44 years. All of them were submitted to transrectal ultrasonography with prostatic biopsy (direct of the lesion and/or suspected area and sextant) previous to the radical surgical treatment. The 522 patients were divided in groups according to the positive fragments found by the biopsy, what was correlated with the anatomicpathologic findings of intraprostatic disease (limited to the gland) and extraprostatic (invasion periprostatic adiposity and/or the bladder neck and/or the seminal vesicles and/or positive pelvic lymph nodes) of the surgical specimen. RESULTS: Regarding the analysis of the positive fragments percentage, the groups G1 (0-25%), G2 (20-50%) and G3 (51-75%) showed an incidence of the intraprostatic disease two and three times greater than the extraprostatic one. However, when more than 75% of the biopsy fragments were positive (G4, 76-100%), the relation inverted occurring a predominance of the extraprostatic disease over the intraprostatic. In this group 56.98% of the patients showed extraprostatic disease. There was a statistically significant difference of the extraprostatic disease between the groups G3 and G4 (p 0.0068). CONCLUSION: When we compared the three inconstant to evaluate the efficiency order anticipating extraprostatic disease, we verified that the preoperative PSA was the most discriminated (p = 0.000000) followed by the Gleason score of prostatic biopsy (p = 0.000003) and by the positive biopsies percentage (p = 0.000574).
Developments in Biological Standardization

developing countries is thought provoking, and so is the paper on environmental standards at the workplace-and the options for setting standards in developing countries. The authors refer to the dilemma of proposing stricter environmental standards for developing countries, because of possible differences in the health status of the population in such countries, versus adopting some practical, achievable, less stringent standard which can be gradually raised. There is also a useful catalogue of vegetable dusts which cause lung disease in developing countries, a good classification of pesticides, and a debatable approach to medical surveillance for exposure to mineral dusts-which advocate medical examinations and chest radiology as a minimum for pneumoconiosis due to mineral dusts. The problem of acute pesticide poisoning and accidents at work in developing countries is highlighted, and these are clearly much bigger problems than in developed countries. It is a fascinating book, well worth reading and definitely to be recommended as a standard text book for occupational health professionals in developing countries. It will also be an eye opener for occupational and public health physicians in developed countries with an interest in approaches to occupational health in the developing world.
Empowerment in Primary Health Care: The Challenge for Nurses

The experience of families of children with persistent middle ear problems supports the notion that when families become empowered, they manage their own health more effectively. Findings from the present study indicate that families engage in predictable processes of acquiescing, helpless floundering, and becoming experts in their efforts at learning to manage the course of their child's disease symptoms within the context of an often cavalier health care system. Questions are raised about the nature of empowerment and the changing role of the nurse.
Epidemiology of low HDL-cholesterol: results of studies and surveys

Low HDL-cholesterol is a risk factor for adverse cardiovascular outcomes independently of levels of LDL-cholesterol. Surveys in individual countries have revealed a substantial prevalence of low HDL-cholesterol, but the utility of data from these studies is limited by differences in study designs and patient populations. Accordingly, the Pan-European Survey of HDL-cholesterol set out to determine the prevalence of low HDL-cholesterol [<1.03 mmol/L (40 mg/dL) in men and <1.29 mmol/L (50 mg/dL) in women] in a large ( n =8545) population of patients receiving treatment for dyslipidaemia under the care of specialist physicians in 11 European countries. Low HDL-cholesterol was present in 33% of men and 40% of women, with very low HDL-cholesterol present in 14% (both genders combined). Hypertriglyceridaemia was present in 49% of men and 45% of women. Low HDL-cholesterol and hypertriglyceridaemia occurred in 22% of men and 25% of women. Low HDL-cholesterol is common among the European population of patients under treatment for dyslipidaemia and thus contributes importantly to overall cardiovascular risk. Interventions to increase HDL-cholesterol have been shown to inhibit atherosclerosis and to improve cardiovascular prognosis in high-risk study populations. Agents that increase HDL-cholesterol should be used in addition to statins, where necessary, to optimize the lipid profile.
The Relationship Between Serum Zinc Levels and Tumor Markers in Hemodialysis Patients

The incidence of neoplasia is increased in end-stage renal disease (ESRD) patients. Zinc (Zn) deficiency is associated with neoplasia and also commonly seen in ESRD patients. However, the data regarding the relationship between Zn levels and tumor markers is scant in this population. We aimed to investigate the relationship between Zn levels and tumor markers in hemodialysis patients. Twenty-six hemodialysis patients (11 male, 15 female, mean age 41.6±14.3 years) and 11 healthy subjects (6 male and 5 female, mean age 38.7±7.2 years) were included. Serum Alpha fetoprotein (AFP), carcinoembriyonic antigen (CEA), CA 19-9, CA 15-5, CA 125, beta subunit of human corionic gonadotrophin (β-HCG) and beta-2 microglobulin (β2M) and Zn levels were measured. Data were analysed by Student’s t test. Serum Zinc levels were significantly lower in ESRD patients (group 1) compared to healthy subjects (group 2) (p<0.0001, for all). Serum CEA and β2M levels were also significantly higher in group 1 patients compared to group 2 subjects (p<0.005, p<0.0001, respectively). Serum Ca15-3 and CA-125 levels were found to be significantly lower in group 1 patients compared to group 2 subjects (p<0.005, p<0.001, respectively). There were no statistically significant difference in terms of serum CA 19-9, β-HCG and AFP between group 1 and group 2 patients. In group 1 patients, there was a negative correlation between serum Zn levels and AFP, while a positive correlation was obsorved between serum Zn levels and CA15-3. The measurement of AFP may be beneficial in HD patients. Further studies are needed