Miracle-dz/UniFAR-FTUs huggingface dataset:
Corporate YouTube practices of Eurozone companies

Purpose – The current study extends the investigation into online relationship building by examining how Eurozone companies belonging to the EURO STOXX 600 index use the popular video platform YouTube to facilitate dialogic communication with their stakeholders. The purpose of this paper is to analyse the extent and main purposes of the channel's usage, the companies’ activities and online practices, as well as the factors on this platform influencing the channel's activity, the audience, and the stakeholders’ engagement. Design/methodology/approach – To achieve this goal a sample of 306 Eurozone companies listed in the STOXX Europe 600 index, including 19 subsectors and 12 countries, have been analysed. Stakeholder and dialogic theory were applied as a theoretical background for this study. Findings – The results indicated that 44 per cent of companies studied have an official YouTube channel, which is mostly used for promotional purposes. It was found that the size of the company, the sector, and its co.
Design and energy optimization of a multifunctional IoT solution for connected bikes

IoT systems face a severe energy autonomy challenge in keeping electronics alive without massive and heavy batteries, pressing for the development of efficient ultra low power architectures and energy harvesting solutions. In this paper we present a new IoT system designed for long-term tracking applications of personal vehicles and moving assets, such as bicycles and carts. The system integrates Cellular, GNSS and BLE communication technologies that enable the implementation of a wide set of geo-aware tracking and fitness monitoring applications. Power consumption minimization is one of the main goals and design challenges for the presented system. This paper focuses on methods and techniques for power consumption optimization at the hardware and software level. We present the design of a miniature kinetic energy harvesting solution and of system architectures for leakage currents minimization and ultra-low power consumption. Results obtained in both simulation and in-field experiments demonstrate high efficiency and performance of the proposed solution, resulting in energy neutral performance of continuous tracking task.
Genetic and biochemical modulation of 5-fluorouracil through the overexpression of thymidine kinase: an in-vitro study

The pro-drug 5-fluorouracil (5-FU) exerts its anti-proliferative action after conversion into cytotoxic metabolites. We previously demonstrated that the anti-cancer action of 5-FU could be enhanced by boosting thymidine phosphorylase (TP) activity in cancer cells, the first step of the DNA pathway, that yields the critical anti-thymidylate synthase (TS) fluorodeoxyuridine monophosphate (FdUMP) metabolite. In the present study, we further studied to what extent 5-FU activity could be optimized by overexpressing cancer cell thymidine kinase (TK), the second step of the DNA pathway, for which controversial data have been published so far. Additionally, screening of biochemical modulators likely to contribute to 5-FU activation was also carried out. TK-overexpressing colorectal cells were obtained after designing vectors harboring viral and human cDNA, and performing stable transfection in the human HT29 cell line. Anti-proliferative assays were subsequently performed so as to evaluate change in cell sensitivity to 5-FU, and metabolism monitoring was carried out to follow drug activation and FdUMP formation after cellular uptake. Finally, TS inhibition was assessed as a pharmacological endpoint. Results showed that overexpression of TK led to a marked desensitization of our model. A negative correlation (r2=0.87) was found between the level of TK activity and 5-FU anti-proliferative action – the higher the activity, the lower the sensitivity. Of the various drugs screened as putative modulators, only those involved in TP activity proved to enhance 5-FU efficacy via optimized FdUMP formation. Conversely, genetically increasing TK activity did not modify 5-FU activation pathway nor subsequent TS inhibition in our model. Therefore, our results indicate that TK is not a limiting step in the production of anti-TS FdUMP and that tumor cells overexpressing TK are likely to resist 5-FU-based chemotherapies.
Literature Review of Customer Service Value and Building Customer Value Model under the Internet Service Situation

The paper summarizes the study of customer service value at home and abroad, including the connotation of customer service value, analysis of the development history and research content, stage division. Through literature analysis, find out the new research hotspot. On the basis of previous research, the paper build customer value model under the situation of Internet service. In order to carry out further research in academic circles of our country to provide reference and reflection.
The long-term effects of using a higher amount of iodine supplement on the efficiency of laying hens

1. Two different levels of dietary iodine supplement (K + 0, 3·57 mg/kg; K + I, 6·07 mg/kg) were used in a 52-week experiment using 32 ISA Brown laying hens. 2. The greater iodine content in the diet impaired the egg production (K + 0, 319·9 ± 1·31 eggs/hen; K + I, 312·4 ± 4·19 eggs/hen), the egg weight (K + 0, 64·4 + 0·66 g; K + I, 63·1 ± 0·61 g) and the food to egg mass ratio (K + 0, 2·13 ± 0·023 kg/kg; K + I, 2·22 ± 0·030 kg/kg). 3. The greater dietary iodine content had significant (P<0·05) negative effects on Haugh units, yolk index and eggshell weight.
Therapeutic use of mistletoe for CD30+ cutaneous lymphoproliferative disorder/lymphomatoid papulosis

558 JEADV 2007, 21, 536–578 © 2006 European Academy of Dermatology and Venereology it has been assessed that the primary defect is not suitable for complete side-to-side closure. It allows the recovery of free tissue as a rotation flap that would otherwise be discarded as a dog-ear. Cosmetic and functional results have been highly satisfactory in all cases, as an excellent match in skin colour and texture has always been maintained This surgical procedure has produced minimal tension across the wound edges, with less scarring and little or no distortion of adjacent anatomic structures. Though mainly applied on the head, the flap has been successfully performed on any anatomic location. According to our experience the comet flap can be a valuable surgical option for closure of round to oval defects of any size in dermatological surgery reconstruction.
Efficiency Study of a Dual-Motor Coupling EV Powertrain

A novel dual-motor coupling powertrain (DMCP) with speed and torque coupling is proposed. In this powertrain, a planetary gear unit couples the speed of two motors, and another shaft-fixed gear unit couples the torque of two motors. By means of integrated control, the electric motors, synchronizer, and clutches, the DMCP can operate in four modes to satisfy the demands of different running conditions, thereby improving the energy utilization efficiency. In this paper, the operating principles of the DMCP in various modes are analyzed, and the instantaneous overall efficiency is optimized based on the vehicle longitudinal kinetic theory. Moreover, this paper formulates the optimal mode shift strategy and the power split strategy of the DMCP, and a detailed dual-motor electric vehicle (EV) model is developed in the MATLAB/Simulink environment. The simulation result indicates that, compared with the normal single-motor two-speed powertrain, the DMCP can effectively improve the energy utilization efficiency of the EV and extends the EV's driving range.
A Study on the Instability of Banking Sector in Iran Economy

It is well-known fact that any country's economic stability depends on financial issues. Among the various issues involved, the stability of banking sector as core of financial and monetary affairs is of prime importance. The present paper intends to study the factors affecting the stability of this sector of Iran economy in both state owned and private banks on the basis of already existing research on banking in Islamic countries. The study is done based on the assumption that the banking system of Iran has the features of Islamic banking and findings indicated that all bank s in Iran had a low level of financial stability within the years 2001 to 2008. It must be noted that the factors affecting financial stability in the case of state owned and private banks are not identical . The macro-variables of net gross domestic product and national currency value have diverse impacts on banking sectors, as the development of the former leads to financial stability and reduction in the case of latter brings financial stability. The balance between the volume of loans and the net assets of the banks is also a variable to be considered, as the increase in loans causes financial instability. It is also found that private banks are prone to be affected by these variables more often when compared to state owned banks.
Are We There Yet?

Research design is a central element of empirical research, and thus, an important consideration for entrepreneurship researchers and anyone interested in entrepreneurship-related research findings. Yet, many years have past since the last thorough review of research design and construct measurement practices. Thus, it is unknown whether there is a gap between what is currently being done versus what needs to be done. In this article, authors use a two-study approach involving a content analysis of published empirical research and a survey of experts within the field to assess the current state of practices. Their findings indicate that, in general, research design and construct measurement practices continue to improve; however, there are some issues that still need to be resolved. Authors lay out key implications and provide several suggestions to help resolve these issues.
Supply chain performance benchmarking study reveals keys to supply chain excellence

Describes a comprehensive set of fact‐based performance measures that can be used to describe accurately a world‐class supply chain of plan, source, make and deliver activities. Aims to help companies take a broad supply‐chain‐process perspective by quantifying performance improvement opportunities across the entire supply chain. Includes quantitative measures such as cash‐to‐cash cycle time and supply chain response time, as well as qualitative analysis of best‐in‐class performance. Best practice benchmarks provide more insight into how to achieve world‐class performance.
Is Blood Thicker than Water? Appraising Adequacy of Indian Corporate Governance for Family Based Companies: A Case Study of Satyam Computers

One third of the Indian companies are controlled by one or another family members in concert. In recent past corporate governance crisis is surfaced in few family controlled business houses. We studied financial & market performance of 44 top Indian companies listed in Forbes Global 2000, which includes 19 family controlled companies. We compared financial & market performance of family based companies with the non-family based companies. It is observed that family based business have higher revenue and profit generating capabilities, but we observed greater fall in market value of their securities during 2008. Our research identified companies, which faced corporate governance problem. It is found that one third of the family based companies have corporate governance problems. Our investigation shows that in spite of strong corporate governance framework & series of legislation in India, top management violates governance norms either to favor family members or due to jealousy amongst sibling. It is found that there is lack of supervision and inefficiency in prosecuting violators. We investigated in detail the recent serious governance failure at India’s 4th largest IT firm, Satyam Computers Services Limited and reasons of such large magnitude failure of checks & balances in action. We have used primary & secondary data to substantiate the conclusion using appropriate research techniques. The research is useful to the policy makers in designing & implementing corporate governance framework in general & special to family based companies.
Characteristic images of deeply infiltrating rectosigmoid endometriosis on transvaginal and transrectal ultrasonography.

BACKGROUND To evaluate the usefulness of transvaginal and transrectal ultrasonography for diagnosis and management of deeply infiltrating rectosigmoid endometriosis. METHODS A series of six patients (aged 32-39 years) with rectosigmoid endometriosis underwent transvaginal and transrectal ultrasonography. In three patients undergoing surgical resection of the intestine, the ultrasonographic findings were compared with macroscopic and microscopic findings. In one patient, sequential observations of the lesion using ultrasonography were conducted before and after medical treatment and following childbirth. RESULTS In all cases, the lesion was detected as a hypoechoic irregular-shaped area surrounded by a hyperechoic rim located posterior to the uterus, with size ranging from 18 x 17 to 29 x 28 mm in diameter. The comparison of the ultrasonographical findings with histology revealed that the hypoechoic irregular-shaped area corresponded to a layer of hypertrophic muscularis propria of the lesion, while the hyperechoic rim represented the layer including the mucosa, submucosa and serosa. In one patient, the lesion decreased in size and lost its central hypoechoic area after childbirth in association with pain relief. CONCLUSIONS Transvaginal and transrectal ultrasonography provides characteristic appearances for rectosigmoid endometriosis that correlate well with its histological findings. The procedures would be useful in the management of rectosigmoid endometriosis.
On How Social Networking Sites Affect Online Consumer Purchase Intention

In view of the prevalence of social networking sites (SNSs) among Internet users and such sites' use in commercial marketing and sales, there has been growing interest in both academia and industry in the study on the effects of SNSs and its various aspects on consumer behavior, inclusive of online consumer purchase intention. In this paper, the effects of the Technology Acceptance Model's constructs, peer influence, and electronic Word-of-Mouth in the context of SNS on online consumer purchase intention are proposed and subsequently tested statistically.
Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques

Significance The Middle East respiratory syndrome coronavirus (MERS-CoV) is the latest emerged coronavirus causing severe respiratory disease with a high case fatality rate in humans. To better understand the disease caused by MERS-CoV, we developed a rhesus macaque model. Infection of rhesus macaques with MERS-CoV resulted in the rapid development of a transient pneumonia, with MERS-CoV replication largely restricted to the lower respiratory tract. This affinity of MERS-CoV for the lungs partly explains the severity of the disease observed in humans. The MERS-CoV rhesus macaque model will be instrumental in developing and testing vaccine and treatment options for an emerging viral pathogen with pandemic potential. In 2012, a novel betacoronavirus, designated Middle East respiratory syndrome coronavirus or MERS-CoV and associated with severe respiratory disease in humans, emerged in the Arabian Peninsula. To date, 108 human cases have been reported, including cases of human-to-human transmission. The availability of an animal disease model is essential for understanding pathogenesis and developing effective countermeasures. Upon a combination of intratracheal, ocular, oral, and intranasal inoculation with 7 × 106 50% tissue culture infectious dose of the MERS-CoV isolate HCoV-EMC/2012, rhesus macaques developed a transient lower respiratory tract infection. Clinical signs, virus shedding, virus replication in respiratory tissues, gene expression, and cytokine and chemokine profiles peaked early in infection and decreased over time. MERS-CoV caused a multifocal, mild to marked interstitial pneumonia, with virus replication occurring mainly in alveolar pneumocytes. This tropism of MERS-CoV for the lower respiratory tract may explain the severity of the disease observed in humans and the, up to now, limited human-to-human transmission.
Emotional stress- and pain-related behaviors evoked by experimental tooth movement.

OBJECTIVE To investigate by behavioral methods the relationship between emotional stress and pain during experimental tooth movement in rats. MATERIALS AND METHODS Sixteen male Sprague-Dawley rats (210 to 250 g) were divided into two groups. The experimental group was treated with an active Ti-Ni appliance, and the control group received a passive appliance. A force of 20 gf was delivered by the active appliance between the maxillary first and second molars for 3 days. During this period the rat's behavior was evaluated eight times by means of open-field test and resistance-to-capture test. The specific parameters of animal activity were facial grooming, rearing, and locomotor activity, movement into the center of the open field, and response to capture. RESULTS Parameters related to stress and pain were higher in the group carrying active appliance, compared to the group with a passive appliance. Statistically significant differences in stress-related behavior between control and experimental groups were found 8 hours after placing the appliance and were most evident on the second day. Pain-related behavior was significantly greater in the experimental group than in the control group at 24 hours. CONCLUSIONS The increase in emotional stress evoked by orthodontic tooth movement may precede the appearance of periodontal pain.
The changing nature of the angel market

This Handbook charts the development of venture capital research in light of the global financial crisis, starting with an analysis of the current venture capital market and the changing nature of the business angel market. Looking at governance structures; the performance of venture capitalists in terms of investments, economic impact and human capital; geographical organization of business angels and venture capital global 'hotspots'; this book also analyses the current state of venture capital research and offers a roadmap for the future.
BANK LENDING, THE IMPACT OF ENVIRONMENTAL FACTORS

In recent years most growing importance is given to the environment and its consequences, so this question becomes an issue not just for manufacturing companies, but also for the banks. In order to prevent threats to the environment, banks bring a new lending operations should be carried out by the environmental risk assessment. In this article, the author's empirical study carried out by looking at the relationship between bank loans and a request for environmental information. In these research took part the biggest Latvian banks, taking into account the corporate lending decisions. The objective of this research paper is to specify environ- mental criteria which should be taken into account in the bank lending decisions. To achieve the goal were used a questionnaire, quantitative and qualitative methods, including the method of sociologic research, monographic and descriptive method.
The effects of obesity, gender, and ethnic group on left ventricular hypertrophy and geometry in hypertensive children: a collaborative study of the International Pediatric Hypertension Association.

OBJECTIVE To determine the prevalence of left ventricular hypertrophy (LVH) in a multiethnic group of children and adolescents with hypertension. DESIGN/METHODS Pooled data from 1998 to 2001 from 3 sites belonging to the International Pediatric Hypertension Association were reviewed. Patients undergoing echocardiography to detect LVH as part of the evaluation for hypertension were included for analysis. Left ventricular mass was calculated from 2-dimensional guided M-mode echocardiographic measurements of the left ventricle. Left ventricular mass index (LVMI) was calculated as left ventricular mass/height(2.7). LVH by adult criteria was defined as LVMI > 51 g/m(2.7) and by pediatric criteria as LVMI > 38.6 g/m(2.7). Left ventricle geometry was classified as concentric, concentric remodeling, eccentric, or normal. RESULTS Data on 129 patients with a mean age of 13.6 +/- 3.6 years were analyzed. The population was 67% male, 46.5% white, 38.0% African American, and 15.5% Hispanic. The prevalence of LVH was 15.5% using adult criteria and 41.1% using pediatric criteria. Increasing body mass index (BMI) was associated with a higher LVMI. Using either pediatric or adult criteria LVH was associated with BMI > or =95th percentile for age and gender. LVH and concentric hypertrophy were identified most frequently in Hispanic children. CONCLUSIONS LVH occurs commonly in children with hypertension and is associated with an increased BMI. LVH may be more prevalent in Hispanic children than in other ethnic groups. Prevention and treatment of obesity is important in reducing the cardiovascular risk for children with hypertension. Further evaluation of the frequency of LVH in multiethnic populations is needed.
Electrode-induced digital-to-analog resistive switching in TaOx-based RRAM devices

In RRAM devices, electrodes play a significant role during the switching process. In this paper, different top electrodes are used for TaOy/Ta2O5−x/AlOσ triple-oxide-layer devices. Top electrode-induced digital resistive switching to analog resistive switching was observed. For Pt top electrode (TE) devices, abrupt digital resistive switching behavior was observed, while Al TE devices showed gradual analog resistive switching behavior. Devices with various AlOσ thicknesses and sizes were fabricated and characterized to evaluate the reliability of the analog resistive switching. The physical mechanisms responsible for this electrode-induced resistive switching behavior were discussed.
Do we have the right kind of diversity in Innovation Policies among EU Member States

This contribution focuses on the heterogeneity in innovation capacity within Europe across its different Member State. Who are the leading and who are the lagging EU countries? Is there a trend towards convergence over time? And how has the crisis affected this trend of convergence? We then take a look at the research and innovation policies which the EU countries have in place and try to assess whether these policies match with the heterogeneous EU countries’ innovation capacity positions. We examine both the budgets allocated by EU Member States to R&I as well as the various kinds of R&I policy programmes being deployed. More particularly, we examine how heterogeneous the deployment of policy instruments is across EU member states and whether this matches with the heterogeneity in innovation capacity development among EU countries. Notwithstanding the large and increasing heterogeneity among EU countries in innovation capacity development, the evidence on innovation policies in EU countries shows a relative homogeneity of policy mixes in different countries. Current innovation policy mixes of instruments do not well reflect the countries’ levels of innovation capacity development.