Miracle-dz/UniFAR-FTUs huggingface dataset:
The comparison of ProSeal and I-gel laryngeal mask airways in anesthetized adult patients under controlled ventilation.

ثيح نم يدعلما بوبنلأا لاخدإ جئاتن ةنراقم :فادهلأا ،يئاوهلا برستلا طغضو ،لاخدلإا حانج ةبسنو ةلوهسو ،تقولا ليس ورب يرجنلحا ءاوهلا ىرجم عانق ينب ةيلمعلا تافعاضمو )I-gel(. ليج يأو )ProSeal( ىفشتسم ،ةحارلجا مسق يف ةساردلا هذه تيرجأُ :ةقيرطلا نم ةرتفلا للاخ كلذو ايكرت ،لوبنطسإ ،نومون ايسابرادياه 80 ةساردلا هذه تلمش دقو .م2014 ليربإ ىلإ م2013 ربمفون نوعضخي نيذلاو اًماع 18-6 ينبام مهرامعأ غلبت نمم اًضيرم يف ينكراشلما ميسقتب انمق دقل .ةئراط ريغ ةيرايتخا ةيلمعل ليس ورب ةعومجم امهو ينتعومجم ىلإ اًيئاوشع ةساردلا ىرجم ةادأ لاخدإب دحاو يئاصخأ ماق مقو .ليج يأ ةعومجمو لاخدإ تقو نم لًاك ليجستب اهللاخ انمقو .ةيرامزلما قوف ءاوهلا لاخدإ ةبوعص كلذكو ،لاخدلإا ءانثأ ةبوعصلا ةجردو ،ةادلأا تافعاضم ىلإ ةفاضلإاب ،يئاوهلا برستلاو ،يدعلما بوبنلأا .ةيلمعلا لقأ ليج يأ ةعومجم يف لاخدلإا تقو لدعم ناك دقل :جئاتنلا يأ( ليس ورب ةعومجم نم ةيئاصحلإا ةيحانلا نم ةحضاو ةروصب حانج لدعم ناكو .)ةقيقد 13±5ليس ورب لباقم 8±3 :ليج )ىلولأا ةلوالمحا نم 100%( ليج يأ ةعومجم يف بوبنلأا لاخدإ نم 82.5%( ليس ورب ةعومجم هتزرحأ يذلا لدعلما نم ىلعأ تيبثت حانج لدعم ناك دقف كلذ ىلإ ةفاضلإاب .)ىلولأا ةلوالمحا نم 92.5%( ليج يأ ةعومجم يف ىلعأ يدعلما بوبنلأا ةلوالمحا نم 72.5%( ليس ورب ةعومجم ىدل هنم )ىلولأا ةلوالمحا . ينتعومجلما ينب ءاوهلا ىرجم برست فلتخي مل اميف . )ىلولأا يرجنلحا ءاوهلا ىرجم عانق جئاتن نأب ةساردلا ترهظأ :ةتمالخا ثيح نم كلذو ليس ورب جئاتن نم لضفأ تناك دق ليج يأ يفنلأا بوبنلأا لاخدإ حانج لدعمو ،لاخدلإا ةلوهسو ،تقولا هذه لثلم لضفأ ةقيرطك اهرابتعا نكيم هنإف كلذلو ،يدعلما . تايلمعلا Objectives: To compare the insertion time, ease of device insertion, ease of gastric tube insertion, airway leakage pressure, and complications between the laryngeal mask airway (LMA) ProSeal (P-LMA) and I-gel (I-gel) groups. Methods: Eighty patients with age range 18-65 years who underwent elective surgery were included in the study. The study took place in the operation rooms of Haydarpaşa Numune Hospital, Istanbul, Turkey from November 2013 to April 2014. Patients were equally randomized into 2 groups; the I-gel group, and the P-LMA group. In both groups, the same specialist inserted the supraglottic airway devices. The insertion time of the devices, difficulty during insertion, difficulty during gastric tube insertion, coverage of airway pressure, and complications were recorded. Results: The mean insertion time in the I-gel group was significantly lower than that of the P-LMA group (I-gel: 8±3; P-LMA: 13±5 s). The insertion success rate was higher in the I-gel group (100%, first attempt) than in the P-LMA group (82.5%, first attempt). The gastric tube placement success rate was higher in the I-gel group (92.5%, first attempt) than in the P-LMA group (72.5%, first attempt). The airway leakage pressures were similar. Conclusion: Insertion was easier, insertion time was lower, and nasogastric tube insertion success was higher with the I-gel application, and is, therefore,
Rigid spine muscular dystrophy due to SEPN1 mutation presenting as cor pulmonale

The nonspecific “rigid spine syndrome” (RSS) is characterized by restricted spine mobility, kyphoscoliosis, reduced vital capacity, and nonprogressive proximal weakness. A subgroup of patients is classified as having rigid spine muscular dystrophy (RSMD), a laminin-α2–positive congenital muscular dystrophy. RSMD linked to chromosome 1p35–361 is caused by mutation in the SEPN1 gene encoding selenoprotein N.2 We describe a patient with RSMD, homozygous for an SEPN1 mutation, who had life-threatening yet reversible right heart failure caused by severe involvement of the diaphragm with nocturnal hypoventilation and pulmonary hypertension. He improved with nocturnal ventilatory assistance. The clinical and genetic findings in his mother and seven siblings are also described. Born to nonconsanguineous healthy parents, the patient was the youngest of 10 children. Developmental motor milestones were normal. Slight difficulty running and climbing stairs, restricted neck movements, elbow contractures, and scoliosis were noted during childhood and adolescence. Family history was unremarkable. He presented at age 26 years with rapidly progressive respiratory and right heart failure with cough, orthopnea, interrupted …
c-Myc and telomerase activation

Comment on: Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes. Alexey V. Bazarov, William C. Hines, Rituparna Mukhopadhyay, Alain Beliveau, Sonya Melodyev, Yuri Zaslavsky, Paul Yaswen. Cell Cycle 2009; 8:In press.
The Search for Perinatal Definitions and Standards

ABSTRACT. Progress made during the last 60 years in reaching international agreement on perinatal terminology is reviewed. Agreed terms currently in use in respect to birthweight, gestational age and the collection of perinatal mortality and morbidity statistics are stated and defined. Arguments are advanced in support of an internationally agreed methodology for the measurement and reporting of infant growth in the perinatal period.
Composition of concurrent programs

A model and a notation are developed for specifying the composition of concurrent programs. The work is based on the observation that the composition of concurrent programs often requires not only intraprocessor coordination but also interprocessor coordination. A notation is developed for explicitly specifying both forms of coordination within a single uniform framework. Much prior work has either ignored the interprocessor coordination aspects of composition, or treated it in a manner separate from the intraprocessor coordination aspects. <<ETX>>
The picasso Package for High Dimensional Regularized Sparse Learning in R

We introduce an R package named picasso, which implements a unified framework of pathwise coordinate optimization for a variety of sparse learning problems (Sparse Linear Regression, Sparse Logistic Regression and Sparse Poisson Regression), combined with efficient active set selection strategies. Besides, the package allows users to choose different sparsityinducing regularizers, including the convex `1, nonvoncex MCP and SCAD regularizers. The package is coded in C and can scale up to large problems efficiently with the memory optimized using sparse matrix output.
Antiinflammatory and analgesic effects of somatostatin released from capsaicin-sensitive sensory nerve terminals in a Freund's adjuvant-induced chronic arthritis model in the rat.

OBJECTIVE We previously demonstrated that somatostatin (SOM) released from the activated peripheral terminals of capsaicin-sensitive primary sensory neurons inhibits acute inflammation and nociception. This study was undertaken to examine this systemic "sensocrine" function of neuronally derived somatostatin in chronic inflammation in the Freund's complete adjuvant (CFA)-induced arthritis model. METHODS Arthritis of the tibiotarsal joint of Lewis rats was evoked by subcutaneous injection of CFA into the left hind paw and the tail root. For 3 weeks, the volume of the paws was measured by plethysmometry, and the mechanonociceptive thresholds were measured by esthesiometry. Plasma concentrations of SOM were determined by radioimmunoassay, and histologic studies of the joints were performed. To impair the function of capsaicin-sensitive afferents, the capsaicin receptor (VR1/TRPV1) agonist resiniferatoxin (RTX) was injected subcutaneously (30, 70, and 100 microg/kg on 3 subsequent days) 7 days before CFA administration. The SOM receptor antagonist cyclosomatostatin (c-SOM; 20 microg/kg) or, in another group, the synthetic heptapeptide agonist TT-232 (2 x 50-400 microg/kg) was administered intraperitoneally every day. RESULTS RTX pretreatment or c-SOM injection significantly increased edema and mechanical hyperalgesia of both CFA-treated and contralateral paws. The histologic score based on synovial thickening, cell infiltration, cartilage destruction, and bone erosion was also significantly higher both in the RTX- and the c-SOM-injected groups. These parameters were dose-dependently decreased by TT-232. Plasma SOM-like immunoreactivity increased 4-fold on the twenty-first day, and was inhibited by RTX pretreatment, as well as by daily administration of TT-232. CONCLUSION Our data suggest that SOM released into the circulation from capsaicin-sensitive afferents in response to prolonged activation exerts systemic antiinflammatory and analgesic effects. TT-232 can open new perspectives in the treatment of chronic arthritis.
Comparison between the efficacy of photodynamic therapy and topical paromomycin in the treatment of Old World cutaneous leishmaniasis: a placebo‐controlled, randomized clinical trial

Background. The optimal treatment for cutaneous leishmaniasis (CL) is not known. Topical paromomycin is one of the many drugs that have been suggested for the treatment of CL caused by Leishmania major. Recently, topical photodynamic therapy (PDT) has been reported to be effective in the treatment of CL.
An outbreak of dengue virus (DENV) type 2 Cosmopolitan genotype in Israeli travellers returning from the Seychelles, April 2017

Dengue virus infection was diagnosed in six Israeli travellers returning from the Seychelles in April 2017. Phylogenetic analysis identified identical sequences belonging to the Cosmopolitan genotype of dengue virus type 2 in all samples sequenced, thus providing evidence for a probable dengue type 2 outbreak in the Seychelles. This report further demonstrates the role of travellers as sentinels for arboviral infections, especially in countries with limited diagnostic capabilities.
Bio compatible magnetic Iron Oxide (Fe3O4) nano particle coated material for reduced wear and debris release — A systematic review

In recent advancements in implant materials, to fight against corrosion and wear, Metal - on - Metal (MoM) hip joints and were used. Though it possess excellent Mechanical properties, the major concern of using MoM implants are, it has high wear, toxicity, corrosion and release of metallic debris in body fluids. The study is intended to investigate the mechanical properties of implant materials like wear, corrosion and release of metallic debris by performing scratch test are analyzed by coating the surface of Metal - of - metal (MoM) implant with magnetic Fe3O4 nano particle. The study is aimed to decrease or prevent the release of metallic debris into body fluids, since the surface of the implant is coated with magnetic Fe3O4 nano particle. Though if wear, corrosion takes place on the surface of the coated material, The nano particles does not escape out of the acetabular cup in which the ball revolves, due to the magnetic property of the coated material.
Effect of benzylpenicillin on the synthesis and structure of the cell envelope of Neisseria gonorrhoeae

The effect of benzylpenicillin on the synthesis and morphology of the cell envelope of Neisseria gonorrhoeae was examined. Penicillin immediately stopped murein synthesis; it also enhanced the rate of turnover of glucosamine, but not diaminopimelic acid, in the murein. In addition, penicillin greatly increased the shedding of lipid and lipopolysaccharide into the medium. In the electron microscope, protrusions of the cell membrane were evident, as well as apparent holes in the murein cell wall. All of these changes occurred while active synthesis was taking place, before the lysis of the cells. Lysis could be prevented by growing the cells at low pH and high concentrations of Mg2+; however, the effects of penicillin on murein synthesis and turnover and on the release of lipid were not affected.
An Out-of-Core Scheme for Simplification of Point-Sampled Models

Most of the exiting point-based simplification methods can't cope with models that are too large to fit in main memory. We present an out-of-core scheme for simplifying large point-sampled models. Firstly, we obtain an initial simplified model using uniform clustering. Then we decimate the redundant details in the flat regions in the condition of keeping the maximum error less than the upper error limit. Finally the same number of details are used to refine the uneven regions. In order to preserve the boundaries of point-sampled models, we design an efficient scheme without using connectivity information. Experiment results show that our simplification method can simplify large models with high quality and low memory usage.
Properties and glial origin of osmotic‐dependent release of taurine from the rat supraoptic nucleus

1 Taurine, prominently concentrated in glial cells in the supraoptic nucleus (SON), is probably involved in the inhibition of SON vasopressin neurones by peripheral hypotonic stimulus, via activation of neuronal glycine receptors. We report here the properties and origin of the osmolarity‐dependent release of preloaded [3H]taurine from isolated whole SO nuclei. 2 Hyposmotic medium induced a rapid, reversible and dose‐dependent increase in taurine release. Release showed a high sensitivity to osmotic change, with a significant enhancement with less than a 5 % decrease in osmolarity. Hyperosmotic stimulus decreased basal release. 3 Evoked release was independent of extracellular Ca2+ and Na+, and was blocked by the Cl− channel blockers DIDS (4,4′‐diisothiocyanatostilbene‐2,2′‐disulphonic acid) and DPC (N‐phenylanthranilic acid), suggesting a diffusion process through volume‐sensitive Cl− channels. 4 Evoked release was transient for large osmotic reductions (≥ 15 %), probably reflecting regulatory volume decrease (RVD). However, it was sustained for smaller changes, suggesting that taurine release induced by physiological variations in osmolarity is not linked to RVD. 5 Basal and evoked release were strongly inhibited by an incubation of the tissue with the glia‐specific toxin fluorocitrate, but were unaffected by a neurotoxic treatment with NMDA, demonstrating the glial origin of the release of taurine in the SON. 6 The high osmosensitivity of taurine release suggests an important role in the osmoregulation of the SON function. These results strengthen the notion of an implication of taurine and glial cells in the regulation of the whole‐body fluid balance through the modulation of vasopressin release.
Cutting Edge: Egress of Newly Generated Plasma Cells from Peripheral Lymph Nodes Depends on β2 Integrin1

During humoral immune responses, naive B cells differentiate into Ab-secreting plasma cells within secondary lymphoid organs. Differentiating plasma cells egress from their sites of generation and redistribute to other tissues, predominantly the bone marrow and mucosal tissues. In this study, we demonstrate that within peripheral lymph nodes newly generated plasma cells localize to medullary cords which express the β2 integrin ligand ICAM-1. In β2 integrin-deficient mice plasma cells accumulate inside the lymph nodes, resulting in severely reduced plasma cell numbers in the bone marrow. Since plasma cells isolated from β2 integrin-deficient animals migrate efficiently into the bone marrow when transferred i.v. , our findings provide profound evidence that β2 integrins are required for the egress of plasma cells from peripheral lymph nodes.
A Dynamic Stochastic Stock-Cutting Problem

We consider a stock cutting problem for a paper plant that produces sheets of various sizes for a finished goods inventory that services random customer demand. The controller decides when to shut down and restart the paper machine and how to cut completed paper rolls into sheets of paper. The objective is to minimize long-run expected average costs related to paper waste (from inefficient cutting), shutdowns, backordering, and holding finished goods inventory. A two-step procedure (linear programming in the first step and Brownian control in the second step) is developed that leads to an effective, but suboptimal, solution. The linear program greatly restricts the number of cutting configurations that can be employed in the Brownian analysis, and hence the proposed policy is easy to implement, and the resulting production process is considerably simplified. In an illustrative numerical example using representative data from an industrial facility, the proposed policy outperforms several policies that use a larger number of cutting configurations. Finally, we discuss some alternative production settings where this two-step procedure may be applicable.
Ambient Backscatterers Using FM Broadcasting for Low Cost and Low Power Wireless Applications

Nowadays, the explosive growth of Internet-of-Things-related applications has required the design of low-cost and low-power wireless sensors. Although backscatter radio communication is a mature technology used in radio frequency (RF) identification applications, ambient backscattering is a novel approach taking advantage of ambient signals to simplify wireless system topologies to just a sensor node and a receiver (RX) circuit eliminating the need for a dedicated carrier source. This paper introduces a novel wireless tag and RX system that utilizes broadcast frequency modulated (FM) signals for backscatter communication. The proposed proof-of-concept tag comprises of an ultralow-power microcontroller (MCU) and a RF front-end for wireless communication. The MCU can accumulate data from multiple sensors through an analog-to-digital converter, while it transmits the information back to the RX through the front-end by means of backscattering. The front-end uses ON–OFF keying modulation and FM0 encoding on ambient FM station signals. The RX consists of a commercial low-cost software-defined radio which downconverts the received signal to baseband and decodes it using a suitable signal processing algorithm. A theoretical analysis of the error rate performance of the system is provided and compared to bit-error-rate measurements on a fixed transmitter-tag-RX laboratory setup with good agreement. The prototype tag was also tested in a real-time indoor laboratory deployment. Operation over a 5-m tag-reader distance was demonstrated by backscattering information at 2.5 kb/s featuring an energy per packet of $36.9~\mu \text{J}$ .
Parenting Style and Students Academic Achievement in Junior Secondary Schools in Ogun State, Nigeria

This paper investigates the influence of parenting styles on the students' academic achievement in Junior Secondary Schools in Ogun state, Nigeria. The study adopted descriptive survey with the sample comprising three hundred and ninety (390) Junior Secondary Students III (JS3). This was selected through random sampling technique from thirteen junior secondary schools in Abeokuta South Local Government Area of Ogun State. Two null hypothesis were formulated and tested at 0.05 alpha to guide the study. A questionnaire titled "Parenting Styles and Students Academic Achievement Questionnaire (PSSAAQ)" was used as instrument for data collected. Data collected were analysed using t-test. The study showed that there was a significant difference between the academic achievement of students from democratic and autocratic parenting homes. Also, a significant difference exists between the level of involvement of parents of male and female students in their education. The paper established the importance of parenting style in the achievement of students. This implies that school alone does not determine student's achievement but a collaborative efforts of home and school. Therefore, the study recommended, among others, that parents should make homes' children-friendly and stop discriminating on sex grounds. The school management was also advised to involve parents and guardians in the academic and moral developments of their wards.
Spatial and Temporal Dynamics in a Sexual Selection Mosaic

Abstract Selective regimes and phenotypic optima could either change smoothly and in a clinal fashion or be spatially organized in a more unpredictable mosaic pattern over the geographic landscape. When natural or sexual selection is driven by intra- or interspecific biotic interactions, fine-grained spatial variation in selective regimes could result in selection mosaics rather than clinal variation in selection. We investigated temporal variation and spatial organization in sexual selection on male body size along an ecological coastal-inland gradient of a polymorphic damselfly Ischnura elegans. Body size increased in a clinal fashion along this gradient: animals were smaller in size at the coast, but became larger in the inland areas. In contrast, the sexual selection regimes on male body size showed evidence of more fine-grained spatial organization with no evidence for a clinal pattern and low spatial autocorrelations between populations. These spatially fine-grained sexual selection regimes varied in sign and magnitude and were driven by a combination of the densities of heritable female color morphs and local female body sizes. We suggest that the spatial organization of the selective regimes can be interpreted as a sexual selection mosaic that is influenced by highly localized density- and frequency-dependent social interactions.
Feasibility of hybrid power generation over wind and solar standalone system

The rapid diminishing rate of gas and oil is alarming us to think about alternative sources. Renewable energy is a better solution to this problem and technologies of extracting energy from renewable energy sources are being upgraded day by day. Our target was to find out the optimum renewable energy source giving best possible power generation. In our research we analyzed the feasibility of power generation using wind and solar energy. For wind property analysis we have used Windowgrapher and for cost analysis we have used Homer. The aim of the study was to analyze the solar and wind characteristics and selecting a suitable location where both solar and wind energy are strong enough for hybrid power generation and choosing suitable PV module and wind turbine for this purpose. We analyzed the beneficiary impact of this hybrid power extraction strategy on our environment and national economy and found that this new technique adaptation can really be useful in off shore islands and high rise buildings of our country.
The biological significance of gaze aversion with particular reference to the syndrome of infantile autism.

Gaze behavior is one of man's most important and frequently used signalling devices. Observation of autistic children at the Park Hospital for Children in Oxford revealed that gaze aversion also appears to have a signalling function, similar to that of “appeasement postures” in certain animals, which serves to inhibit aggression on the part of others. The paper presents an investigation of the social encounters of autistic children, using film records of the children's behavior to illustrate the authors' findings.
Nucleologenesis and the onset of transcription in the eight‐cell bovine embryo: Fine‐structural autoradiographic study

Eight‐cell cow embryos were isolated and cultured in vitro in a medium enriched with 200 μCi of [5‐3H]uridine for 20 min. Epon ultrathin sections of the embryos were investigated for the nucleolar morphology and for the appearance and localization of the sites of [5‐3H]uridine incorporation by means of electron microscopic autoradiography. In addition to this, a general pattern of replicated embryonal DNA distribution was revealed by [methyl‐3H]thymidine incorporation and light microscopic autoradiography.
Tonic Potentiation And Attenuation Produced By Membrane Depolarization In Guinea‐Pig Trachealis

1. We studied how membrane depolarization directly affected intracellular Ca2+ signalling when voltage‐operated Ca2+ channels (VOCC) were not available in guinea‐pig tracheal smooth muscle. To block VOCC, we used 3 μmol/L verapamil, which completely abolished high K+ (20–60 mmol/L)‐induced contraction, and elevation of fura‐2 signal.