Miracle-dz/UniFAR-FTUs huggingface dataset:
Second branchial cleft anomalies: a review of 12 cases

Background: It is a combined retrospective and prospective study of 12 cases of branchial cleft anomalies presented to our hospital. We analysed them for their age and sex incidence, side prevalence, according to clinical features and treatment outcomes.Methods: Thorough history was taken and examination was done and these cases are investigated with CT scan, MRI scan and treated with surgical excision. Results: Cyst is seen in 7 (58.33%) patients while one case of sinus and one (8.33%) of fistula,1 case of co-existing sinus and fistula (8.33%), and one Bilateral sinus and 1 bilateral fistula (8.33%) were seen. Overall incidences of branchial anomalies are more (40%) in 11-15 year age group. Overall incidence of branchial anomalies is more in male (66.66%) than female (33.33%). 4 cysts were right sided and 3 were left sided. Sinus and fistula were seen one case having right sided and 1 case having bilateral anomaly. Patients having branchial cysts presents most commonly with neck swelling and pain while patients having fistula and sinus presents commonly with discharging opening over anterior neck. 1 case of recurrence found in cyst on follow up and no recurrences were seen in sinus and fistula.Conclusions: Cyst is the most common anomaly, most commonly affected age group is 11-15 years, male are more commonly affected, these anomalies are more prevalent on right side, and there are very less chances of recurrence after surgical excision.
A non-canonical unfolded protein response pathway and mitochondrial dynamics control the number of ER-mitochondria contact sites

Mitochondria maintain their morphology and functions through the optimized balance between the mitochondrial fusion and division. Here we report a novel role of mitochondrial dynamics in controlling the number of ER-mitochondria encounter structure (ERMES) clusters in a yeast cell. Loss of mitochondrial fusion or division caused the increased or decreased number, respectively, of ERMES foci observed in cells. ERMES complexes, therefore, appear to cluster with each other and mitochondrial division may inhibit undesired ERMES hyper-clustering. Furthermore, our microscopic analyses suggest that ER stress induces dissociation of ERMES clusters, increasing the number of ERMES foci even in the absence of Ire1 and Hac1, which are essential factors for the UPR response. Interestingly, we found that ER stress leads to expansion of both the ER and mitochondrial membranes in an ERMES function-dependent manner. These findings imply that a cell is equipped with two independent regulatory mechanisms controlling the number of ER-mitochondria contact sites to meet the cellular as well as environmental demands.
Can sport-specific training affect vertical jumping ability during puberty?

Vertical jumping ability (VJ) is an important component for successful performance in various team sports such as volleyball, basketball, and soccer. There is evidence that the sport-specific training in these sports may affect the development of VJ throughout the developmental years. Thus, the main objective of this study was to investigate the sport-related effect (volleyball, basketball, soccer) on vertical jumping ability (VJ) and on the stretch-shortening cycle (SSC) during puberty. 320 boys (12–15 years old) – 80 basketball players (BP), 80 soccer players (SP), 80 volleyball players (VP) and 80 non-athletes (NA) – participated in the present study. VJ was evaluated by the squat jump (SJ) and countermovement jump (CMJ) tests, and the contribution of SSC was calculated. The SJ and CMJ were significantly higher in VP vs. NA at the age of 12 years old and significantly greater in all sports vs. NA at the age of 13, 14 and 15 years. Furthermore, 15-year-old VP demonstrated significantly higher SJ and CMJ compared with BP and SP (p<0.01), whereas no differences were observed between BP and SP (p>0.05). Finally, pairwise comparisons revealed non-significant sport- and age-related differences (p > .05) in SSC. The pattern of age-related increase in VJ is different between athletes and non-athletes during puberty. Furthermore, sport-specific training adaptations are evident at the age of 15 years old where VP demonstrate greater VJ than BP and SP, while in younger age groups, there are no significant differences in VJ between athletes of different sports.
Manual De Neonatologia

El formato esquemático proporciona a los lectores un acceso rápido a grandes cantidades de valiosa información sobre problemas maternos, fetales y neonatales, así como sobre procedimientos neonatales habituales. El manual también incluye los populares apéndices sobre temas como guías de medicación para la unidad de cuidados intensivos neonatales, los efectos de la medicación materna en el feto y los problemas neonatales, así como la administración de medicaciones durante la lactancia. También se presentan guías de intubación/sedación y una guía de reanimación neonatal que proporcionan información fundamental en un formato rápido y accesible.
E-Clinical High Risk for Psychosis: Viewpoint on Potential of Digital Innovations for Preventive Psychiatry

E-mental health is an emerging area of research that has the potential to overcome some of the current barriers to progress in working with people at clinical high risk for psychosis (CHR-P). This article provides an overview of how e-mental health could be used in the detection, prediction, and treatment in the CHR-P population. Specifically, we evaluate e-detection, e-prediction, and e-therapeutics for this clinical population. E-mental health holds great promise to improve current management of CHR-P individuals.
Pinch-induced behavioural inhibition (clipthesia) as a restraint method for cats during veterinary examinations: preliminary results on cat susceptibility and welfare.

Cats are often subjected to minimally painful or forced procedures during routine clinical practice, which can be poorly tolerated, leading veterinary surgeons to need to offer physical restraint, usually aided by an assistant. The aim of this study was to assess the effectiveness and ultimate welfare implications of using clipthesia as a method of restraint during veterinary examination. This was carried out in a real clinical setting and compared to manual scruffing. Twenty-seven cats were restrained, during a veterinary examination, using two stationery clips placed on the skin along the cervical dorsal midline, whilst a group of 13 cats were restrained through gentle manual scruffing. Susceptibility to clipthesia (ie a positive clip score) was observed in 81.5% of cats, while a complete response was found in 40.7% of subjects. The presence or absence of a disease/condition did not affect the susceptibility. Heart rate and the number of cats showing mydriasis (pupillary dilation) was statistically higher during manual scruffing, whilst plasma cortisol did not differ between the two groups. The more responsive the cats were to clipthesia, the more they displayed kneading and purring. These preliminary findings suggest that clipthesia is not more stressful than manual scruffing in restraining cats during a veterinary examination. However, not all cats were found to be susceptible to this method of restraint. Further research is needed to clarify whether clipthesia should be implementated as a matter of course in veterinary practice from the point of view of welfare and safety.
Time-Critical Visual Exploration of Scalably Large Data

This paper discusses visualization and analysis issues as datasets grow towards very large sizes, and it develops an approach to attack these issues. Datasets of this size become exploration-dominant since the scientists who create or collect them do not know, in detail, what's inside. Thus the methods developed here support exploratory visualization. To be fully successful these methods must be fast, so issues of time-criticality are addressed. Fast global overviews are prepared automatically based on an analysis of patterns in the data. From these, particular overviews can be generated followed by detailed subviews, where these last steps are controlled by user interaction. A particular approach is developed to recognize spatial clustering in 3D data, and this is applied to a variety of datasets. The performance of the approach as a function of dataset size is analyzed, and it is found that it holds promise for the exploration of large datasets. In addition an octree decomposition method is also developed as an adjunct to the clustering method. Both methods can be used to develop hierarchical structures for the datasets, which can be extended by user interaction. Information derived from the methods can be analyzed so that patterns in the datasets can be segmented according to shape, size, dynamic behavior, or content
MONTE CARLO-FD COMPREHENSIVE METHOD FOR RELIABILITY EVALUATION OF AC/DC HYBRID NETWORK SYSTEMS

A new method named Monte Carlo FD Comprehensive Method in which the two classical methods (simulation analysis) can be combined for reliability evaluation is presented in this paper. Based on the actual operation condition of AC/DC hybrid network systems, the reliability equivalent model is investigated in detail. The stochastic simulation method for the whole AC/DC hybrid network systems is discussed. The scheduled maintenance and criterion for N 1 and N 2 faults are analyzed. Two actual situations are distinguished according to whether power flow is regulated or not. Then the state analysis approach of the system is described. Besides, precision control for simulation is introduced. Reliability evaluation of a 500kV hybrid network system shows that the method proposed in this paper is of great success in improving simulation speed and precision.
Methylation Status of Promoter Region of Tumor Necrosis Factor Alpha Gene in Subjects with Healthy Gingiva and Chronic Periodontitis - A Pilot Study.

Periodontitis is a multi-factorial disease with bacterial origin. The progression is influenced by systemic disease, smoking, genetic factors. In the recent past epigenetic influences have been indentified on the candidate genes which code for proteins that play a role in the pathogenesis of the periodontal disease. Epigenetic mechanisms involve DNA methylation and histone modification. Till date, there is no existing data associating methylation status of the promoter region (-239, -245) of the TNF alpha gene and chronic periodontitis. The objective of this study was to compare the methylation status of CpG islands in the promoter region of TNF alpha (-239, -245) gene in the peripheral blood among subjects with healthy gingiva and chronic periodontitis. A case control study design involving 50 subjects (25 healthy and 25 subjects with chronic periodontitis) was performed. DNA was isolated from peripheral blood of all the subjects and bisulfate modification with methylation specific polymerase chain reaction (MS-PCR) was performed. The methylation status of the selected region of the Tumor necrosis factor alpha gene for both the test and control groups was evaluated and assessed. The mean Ct value for the methylation of control group was 24.36 and in the periodontitis group the mean Ct value was found to be 28.09. The higher the Ct value, the lower is the amount of methylation observed. The periodontitis group had a higher mean Ct value as compared to the control group; indicating a lower amount of methylation in the promoter region of the periodontitis group as compared to the control group. A lower level of TNF alpha gene promoter (-239,-245) methylation was observed in the periodontitis group as compared to the controls and this observation appears to support a de-methylation of the TNF alpha promoter in the periodontitis subjects. Further studies evaluating the transcript levels of TNF alpha needs to be performed to confirm the observations of this study.
Effect of Bacillus mesonae H20-5 on Fruit Yields and Quality in Protected Cultivation

Sung-Je Yoo, Jeong Woong Kim, Sang Tae Kim, Hang-Yeon Weon, Jaekyeong Song, and Mee Kyung Sang * Division of Agricultural Microbiology, National Institute of Agricultural Science, Rural Development Administration, Wanju 55365, Korea Department of Agriculture, Biotechnology and Natural Resources, Gyeongsang National University, Jinju 52828, Korea Central Research Institute, Kyung Nong Corporation, Gyeongju 38175, Korea Department of Applied Bioscience, Dong-A University, Busan 49315, Korea
Application of Rough Set and Decision Tree Theory to Inspection of Power Transmission Line

As the inspection demands of the transmission,it is necessary to enhance the efficiency of power inspection. Taking all factors which have significant effects on the running status of the transmission lines into consideration,this system establishes a state prediction model of transmission line based on rough set theory and decision tree.The rules which extract from the model apply in the abnormity prediction of the transmission lines.The manager car.work out a scientific and reasonable inspection plan in accordance with these rules.This model is proven and have a higher accuracy.
General uncertainty relations and sparse signal recovery

The Nyquist-Shannon sampling theorem is undoubtedly one of the most fundamental results in signal processing. It says that a signal has to be sampled at a rate at least twice the maximum frequency present in the signal in order to perfectly recover it from its samples. In recent years, it was shown that additional information or assumptions about the signal can be exploited to significantly reduce this required rate of sampling. The key assumption turns out to be sparsity, i.e., if the spectrum is only sparsely occupied, it can be shown that the signal can be sampled at (significantly) lower rates than the Nyquist-rate. This surprising discovery is a consequence of the advances in the field of sparse signal recovery, where one is concerned with finding sparse solutions of underdetermined linear systems of equations. In this thesis, building on the landmark results by Donoho and Stark (1989) and Elad and Bruckstein (2002) that demonstrated the fundamental connection between uncertainty relations and sparse signal recovery, we present novel and improved sparse signal recovery guarantees. In the first part of this thesis, we present a novel uncertainty relation for the representation of signals in two different general (possibly redundant or incomplete) signal sets. Based on this novel uncertainty relation, we derive improved sparsity thresholds guaranteeing perfect recovery of signals that are sparse in general dictionaries. Specifically, our results can improve on the well-known (1 + 1/μ)/2-threshold for dictionaries with coherence μ by up to a factor of two. Moreover, we provide probabilistic recovery guarantees that allow us to understand which part of a general dictionary one needs to randomize over to
Dopamine's role in risk taking: a specific look at dopamine deficiency and gambling

IntroductionThe mesolimbic dopamine (DA) system is thought to be important for reward-based decision-making. Dysfunction of this system is implicated in impulsivity. Many neuropsychiatric disorders, such as drug addiction, obesity and pathological gambling, are characterized by a relative oversensitivity to reward and insensitivity to negative outcomes, as well as impulsivity. The administration of DA agonists in some patients with Parkinson's disease (PD) can trigger unusually risky behavior, such as pathological gambling and compulsive sexual behavior, which are impulse control disorders (ICD). Interestingly the risk factors predisposing PD patients to ICDs closely resemble those associated with drug addiction in the general population. PD patients who develop ICDs have risk factors similar to non-PD patients who develop addictions, possibly due to a similar underlying neurobiological mechanism. We asked two questions. 1) Are there underlying abnormalities in the neural processing of risky decision-making in PD, specifically those who develop ICDs? 2) What role does DA plays in risky decision-making in young healthy subjects: without the limiting factor of age, disease or pathology.MethodsExperiment 1 used functional magnetic resonance imaging (fMRI) to look at differences in neural activation during gambling in PD patients who had a history of ICDs due to DA agonist treatment (n=11, PD-ICD) compared to their disease (n=12, PD-CON) and age-matched controls (n=11, AM-CON). Experiment 2 tested the relationship between DA level and performance on a gambling and probabilistic selection task, using the acute phenylalanine/tyrosine depletion (APTD) method, fMRI and [11C]raclopride positron emission tomography (PET), in healthy subjects 18- 30 years of age (n=17). ResultsExperiment 1: (1) Individual predisposition to ICDs is evidenced by differences in personality, betting strategies and evaluation of financial risk. (2) The PD-ICD group showed dysfunction in the weighting of losses relative to gains both behaviourally and neurally. (3) The ventral striatal (VStr) reward prediction error signal is not necessary to develop and maintain behavioural addictions. And (4) Abnormality in the insular cortex's evaluation of risk and reward, and perhaps that of the mesocorticolimbic network in general, may be the main neural correlate mediating susceptibility for the development of an ICD in PD.Experiment 2: (1) APTD-induced lowering of brain DA led to an increase in loss aversion and an increased ability to learn from negative outcomes; the greater the depletion, the greater the improvement in punishment accuracy. (2) High impulsivity scores were correlated with high baseline D2 receptor levels, which may index low tonic DA and susceptibility to high phasic DA neuron firing. (3) The BOLD signal was correlated with the expected value and reward prediction error in the VStr bilaterally, however, this correlation was significantly increased after DA depletion, suggesting that the striatal BOLD signal in that area is not a direct…
Face detection based on cascaded boosting algorithm

An algorithm based on Cascaded Boosting for human face detection was proposed.Firstly,the PCA was used to extract the feature from human face images,and integrate historical information into successive boosting learning.Based on linear recursive feature elimination(RFE) strategy,the redundancy of AdaBoost was removed.The ORL face database was used to test the proposed method.Experiment results shows that the method is effective and good detective performance is achieved.
Pengaruh Pendampingan MP-ASI Berdasarkan Aspek Pengetahuan Ibu dan Praktik Pemberian MP-ASI Balita Gizi Kurang Usia 6-24 Bulan di Wilayah Kerja Puskesmas Ngawen Kabupaten Blora

Background : Under Weight is a health problem that occurs in developing countries like Indonesia. The prevalence of malnutrition nationally as much as 19.6%. The prevalence of under weight in Central Java 18% and in CHC Ngawen 14.8%. Objective: To describe the effect of nutritional assistance based on affect of mothers knowledge and feeding practices for children under weight 6-24 months age in CHC of Ngawen Blora. Methods: There was a quasi-experimental design pre and post test control group gesign with 38 samples. The intervention group received nutrition assistance for 1 month with 3 sessions (intensive, reinforcement, self). Data analysis used Annova Repeated Measure. Results: The average knowledge of the mother before and after assistance, was 78.0 and 89.26. The average of feeding practice before and after assistance was 70.62 and 85.6. Conclusion: There were differences in the knowledge scores of mothers and provision of complementary feeding practices between the control and intervention groups after being given assistance (p=0.094 and p = 0.073). Research for the effect of nutrition assistance program should be implemented to the nutritional status of children 6-24 months ages malnutrition
Molecular analysis of Hydra embryonic development by means of subtractive hybridization

Pattern formation, morphogenetic movements and extensive processes of cell proliferation and differentiation are hallmarks of embryogenesis. Yet freshwater Hydra undergoes all these processes in adult asexual state, and was traditionaly considered to be a constant embryonic model. However, we have previously demonstrated that the timing of expression of regulatory genes differs significantly between in embryos and during patterning events in the asexual polyps. In this thesis the result of an unbiased search for genes upregulated during embryonic development in contrast to adult morphogenetic events is presented. Sequencing of the subtracted cDNA library yielded 76 clusters and 12 singletons, and many of these clusters and singletons represented putative novel genes. A homologue of the conserved Polycomb group regulatory gene Embryonic Ectoderm Development was cloned in this experiment and characterized in detail. It turned to be the earliest known marker of the multipotent interstitial stem cells, and allowed to trace their origin to the endoderm of the embryo.
Simulation Optimization: A Concise Overview and Implementation Guide

Simulation optimization (SO) is the problem of optimization in the presence of objective and constraint functions that can only be observed via a stochastic simulation. SO, owing to its flexibility, has recently grown in popularity among practitioners as a convenient formulation for optimization under uncertainty. The last two decades have also seen a parallel growth in algorithmic methodology for solving SO problems. This tutorial provides a concise guide to the state of the art for solving a few key flavors of SO. Our intended target audience is a sophisticated practitioner who is looking for algorithmic implementations (http://www.simopt.org) for solving an SO problem, or a researcher who is looking to be gently initiated into the vast SO literature. Accordingly, our discussion throughout this tutorial is kept at a very accessible level—no theorems are presented, but an attempt has been made to retain key technical details. Whenever possible, we provide pointers to stable algorithmic implementations, and good entry points into the literature.
The strategies behind "inside-out" and "outside-in" endoscopy of the lumbar spine: treating the pain generator.

Two conceptually different transforaminal endoscopic methods of accessing and decompressing the lumbar intervertebral discs have emerged over the years: the “inside-out,” and the “outside-in” technique. While the distinction between these two methods driven by the initial placement of the endoscopic working cannula either inside the intervertebral disc (inside-out) or into the neuroforamen (outside-in) seems somewhat trivial on the surface, it is far from it when one looks beyond the access issue. The differences go much deeper than the initial starting point, considering which of the common pain generators can be directly visualized and treated.