Miracle-dz/UniFAR-FTUs huggingface dataset:
An automated quantitative content analysis process for humanitarian logistics research

Purpose Access to high-quality data is a challenge for humanitarian logistics researchers. However, humanitarian organizations publish large quantities of documents for various stakeholders. Researchers can use these as secondary data, but interpreting big volumes of text is time consuming. The purpose of this paper is to present an automated quantitative content analysis (AQCA) approach that allows researchers to analyze such documents quickly and reliably. Design/methodology/approach Content analysis is a method to facilitate a systematic description of documents. This paper builds on an existing content analysis method, to which it adds automated steps for processing large quantities of documents. It also presents different measures for quantifying the content of documents. Findings The AQCA approach has been applied successfully in four papers. For example, it can identify the main theme in a document, categorize documents along different dimensions, or compare the use of a theme in different documents. This paper also identifies several limitations of content analysis in the field of humanitarian logistics research and suggests ways to mitigate them. Research limitations/implications The AQCA approach does not provide an exhaustive qualitative analysis of documents. Instead, it aims to analyze documents quickly and reliably to extract the contents’ quantifiable aspects. Originality/value Although content analysis has been used in humanitarian logistics research before, no paper has yet proposed an automated, step-by-step approach that researchers can use. It also is the first study to discuss specific limitations of content analysis in the context of humanitarian logistics.
Neutralization of IL‐17 by active vaccination inhibits IL‐23‐dependent autoimmune myocarditis

The most common reason for heart failure in young adults is dilated cardiomyopathy often resulting from myocarditis. Clinical studies and animal models provide evidence that an autoimmune response against heart myosin is the underlying reason for the disease. IL‐12 has been suggested to play a key role in development of experimental autoimmune myocarditis (EAM), as IL‐12p40 and IL‐12Rβ1 knockouts are protected from disease. In this study, we have compared IL‐12p40–/– mice, IL‐12p35–/– mice and mice treated with a neutralizing IL‐23 antibody in EAM and found that in fact IL‐23, not IL‐12, is responsible for inflammatory heart disease. However, these cytokines appear to have redundant activity for priming and expansion of autoreactive CD4 T cells, as specific T cell proliferation was only defective in the absence of both cytokines. IL‐23 has been suggested to promote a pathogenic IL‐17‐producing T cell population. We targeted IL‐17 by capitalizing on an active vaccination approach that effectively breaks B cell tolerance. Neutralization of IL‐17 reduced myocarditis and heart autoantibody responses, suggesting that IL‐17 is the critical effector cytokine responsible for EAM. Thus, targeting of IL‐23 and IL‐17 by passive and active vaccination strategies holds promise as a therapeutic approach to treat patients at risk for development of dilated cardiomyopathy.
Decoding under integer metrics constraints

We investigate the problem of decoding digital data when soft decisions are constrained to take on values from a finite set. We propose a physically reasonable objective function for selecting the desired assignment of metrics to the received analog signals. We develop a search algorithm for designing a table-look-up that is used by the decoder to select the appropriate intermediate metrics and show that an optimum solution exists. We provide a number of illuminating examples to elucidate our ideas and work out in detail some practical cases. >
Lack of association of apolipoprotein E allele epsilon 4 with late-onset Alzheimer's disease among Finnish centenarians.

No association between Alzheimer's disease (AD) and apolipoprotein E type epsilon 4 (ApoE epsilon 4) phenotype was found among centenarians in Finland (N = 179). The data are based on ascertainment of all centenarians in Finland in 1991. All examinations were conducted during 1991. The diagnoses of dementia and AD were based on clinical grounds, conforming to DSM-III-R and NINCDS-ADRDA criteria. The percentage of ApoE epsilon 4 alleles among the centenarians was 8.7% (31 of 358 alleles). This is significantly lower than percentages found in younger Finnish populations. Thirty (16.8%) of the 179 centenarians were epsilon 4 allele carriers. One hundred fifty-one (84.4%) of the centenarians were women. Twenty-eight (18.5%) of the women had at least one epsilon 4 allele, as did two (7.1%) of the men. The prevalence of clinically diagnosed AD was 26.8%; 44% of the subjects were cognitively normal, 23% had signs of cognitive decline or at most mild dementia (with no differential diagnosis), and 6% had a dementia clinically diagnosed as being due to some cause other than AD. For AD cases versus cognitively normal subjects, the odds ratio associated with being a carrier of the epsilon 4 allele was 1.34 (p = 0.64; 95% CI = [0.5, 3.3]). Among women, the odds ratio was 0.99 (p = 1.0; 95% CI = [0.4, 2.6]). There were fewer, but not significantly so, epsilon 4 carriers among subjects with cognitive decline or at most mild dementia (12.2%) than there were among the cognitively normal subjects (16.5%). The AD patients had no evidence of difficulty standing on a flat stationary surface unless the surface suddenly moved. (ABSTRACT TRUNCATED AT 250 WORDS)
TenantGuard: Scalable Runtime Verification of Cloud-Wide VM-Level Network Isolation

The multi-tenancy of a cloud usually leads to security concerns over network isolation around each cloud tenant's virtual resources. However, verifying network isolation in cloud virtual networks poses several unique challenges. The sheer size of virtual networks implies a prohibitive complexity, whereas the constant changes in virtual resources demand a short response time. To make things worse, such networks typically allow fine-grained (e.g., VM-level) and distributed (e.g., security groups) network access control. Those challenges can either invalidate existing approaches or cause an unacceptable delay which prevents runtime applications. In this thesis, we present TenantGuard, a scalable system for verifying cloud-wide, VM-level network isolation at runtime. We take advantage of the hierarchical nature of virtual networks, efficient data structures, incremental verification, and parallel computation to reduce the performance overhead of security verification. We implement our approach based on OpenStack and evaluate its performance both in-house and on Amazon EC2, which confirms its scalability and efficiency (13 seconds for verifying 168 millions of VM pairs). We further integrate TenantGuard with Congress, an OpenStack policy service, to verify the compliance of isolation results against tenant-specific high level security policies.
THE INVESTIGATION OF HOTELS IN THE NORTHERN PARTS OF THAILAND FOR FOREIGN TOURISTS TO THE QUALITY OF SERVICES

The research aimed 1) to study the investigation of a hotel in the northern areas of Thailand for Foreign Tourists to the quality of services; and 2) to compare the happiness of foreign tourists toward service quality of hotels in the Northern Areas of Thailand by demographic profiles. A questionnaire was used as a research tool for collecting data from a sample of 450. The data were analyzed for descriptive statistics: percentiles, means and standard deviations (S.D.) while inferential statistics used were Independent-Sample t-test, One-Way ANOVA (F-test), and using Least Significant Difference (LSD) test to compare each pair at the significance level of 0.05. The results in this study revealed that the overall happiness of foreign tourists toward service quality in the Northern Areas of Thailand was high (xˉ = 3.98). When looking at each item, the results demonstrated that responsiveness was (xˉ = 4.03), assurance (xˉ = 4.01), reliability (xˉ = 3.98), empathy (xˉ = 3.98), and tangibility (xˉ = 3.90) respectively. The levels of happiness results in comparison in this study showed that different demographic factors of foreign tourists in terms of age, education, domicile, career, and monthly income affected the levels of happiness at the significance level of 0.05; meanwhile, the demographic factors in terms of gender and marital status did not differently affect the levels of happiness at the significance level of 0.05.
A Workload-Specific Memory Capacity Configuration Approach for In-Memory Data Analytic Platforms

Nowadays, in-memory data analytic platforms, such as Spark, are widely adopted in big data processing. The proper memory capacity configuration has been proved to be an efficient way to guarantee the workload performance in such platforms. Currently, Spark adopts the static way to configure the memory capacity for workloads based on user specifications. However, due to the lack of deep knowledge of the target platform and workload characteristics, nonexpert users often conservatively configure the memory capacity in an excessive way, which reduces the memory utilization significantly. On the other hand, as the memory requirements are quite different among diverse workloads, there is not the one-size- fits-all solution for memory capacity configuration. Aiming on these issues, we propose WSMC, a workload-specific memory capacity configuration approach for the Spark workloads, which guides users on the memory capacity configuration with the accurate prediction of the workload’s memory requirement under various input data size and parameter settings. First, WSMC classifies the in-memory computing workloads into four categories according to the workloads’ Data Expansion Ratio. Second, WSMC establishes a memory requirement prediction model with the consideration of the input data size, the shuffle data size, the parallelism of the workloads and the data block size. For the ad-hoc workload, WSMC can profile its Data Expansion Ratio with small-sized input data and decide the category that the workload falls into. Users can then determine the accurate configuration in accordance with the corresponding memory requirement prediction.Through the comprehensive evaluations with SparkBench workloads, we found that, contrasting with the default configuration, configuration with the guide of WSMC can save over 40% memory capacity with the workload performance slight degradation (only 5%), and compared to the proper configuration found out manually, the configuration with the guide of WSMC leads to only 7% increase in the memory waste with the workload’s performance slight improvement (about 1%)
Theoretical Model on Impact of New Media Communication to Female Consumers Behavior —Taking Female APP Communication as Example

New media is bringing great influence to business mode and social structure. The mobile APP that is a kind of new media brings not only convenience to female lives, but also huge economic benefits to many industries. Based on the theories of communication and consumers behavior, using the methods of depth interview and literature research, this paper analyzes the mechanism that female APP communication affects the female consumer behavior; and puts forward hypothesis and constructs a theoretical model by following the analytic logic: consumers perception to female APP communication—female consumers intention—female consumers behavior. It takes the lead to do the research in the unified theoretical model. Systematic researches of interaction effects of these variables are also preceded under the situation of new media. The theoretical model provides a new tool of scientific and explanatory power to illustrate the influence on new media communication to female consumers’ behavior. Keywords—new media; female APP communication; consumers perception; consumers behavior
Ladder‐shaped lymphaticovenular anastomosis using multiple side‐to‐side lymphatic anastomoses for a leg lymphedema patient

Lymphatic supermicrosurgery, supermicrosurgical lymphaticovenular anastomosis (LVA), is becoming a useful option for the treatment of compression‐refractory lymphedema. One of the most important points in LVA is to make as many bypasses as possible for better treatment results. We report a progressive lower extremity lymphedema (LEL) case successfully treated with a ladder‐shaped LVA. A 67‐year‐old female with secondary LEL refractory to conservative treatments underwent LVA. A ladder‐shaped LVA was performed at the left ankle. In the ladder‐shaped LVA, 3 lymphatic vessels and 1 vein were anastomosed in a side‐to‐side fashion; 2 lymphatic vessels next to the vein were anastomosed to the vein, and the other lymphatic vessel was anastomosed to the nearby lymphatic vessel. Using ladder‐shaped LVA, 6 lymph flows of 3 lymphatic vessels could be bypassed into a vein. Six months after the LVA operation, her left LEL index decreased from 212 to 195, indicating edematous volume reduction. Ladder‐shaped LVA may be a useful option when there are 3 lymphatic vessels and 1 vein in a surgical field. © 2013 Wiley Periodicals, Inc. Microsurgery 34:404–408, 2014.
Adhérence de cellules uniques sur supports micro-structurés

L'adherence cellulaire est un processus vital implique dans de nombreux phenomenes biologiques fondamentaux comme la dierenciation, la reparation tissulaire ou encore le developpement cellulaire. Cette these porte sur une etude alliant experiences et modelisation de cellules uniques en adherence sur des supports micro-structures Les resultats montrent que la contrainte geome- trique imposee par les supports a contraste adhesif limite l'adherence. Au-dela de cette limitation, une organisation reproductible du cytosquelette d'actine est observee cela suggere l'existence de lois physiques simples regissant ce processus. Nous avons developpe une methode de classication des formes geometriques elementaires observees experimentalement nous permettant d'obtenir des statistiques robustes. En nous basant sur le modele de Potts Cellulaire, nous avons pu reproduire les resultats experimentaux. Ce modele energetique demontre que les formes elementaires sont des etats metastables utilises par les cellules au cours de l'adherence. Les parametres du modele sont relies aux parametres biologiques pertinents. Nous presentons des resultats qui relient la courbure des interfaces aux parametres biologiques. Nous montrons que la mesure experimentale de cette courbure est une representation de la competition entre la contractilite des bres de stress et l'elasticite du gel d'actine. Une correspondance entre les proprietes physiques issues du modele et les processus biochimiques regulant et organisant l'adherence cellulaire est ainsi possible.
RHAETIAN (LATE TRIASSIC) MONOTIS (BIVALVIA: PECTINOIDA) FROM THE EASTERN NORTHERN CALCAREOUS ALPS (AUSTRIA) AND THE END‐NORIAN CRISIS IN PELAGIC FAUNAS

Abstract: Species of marine bivalves of the pectinoid genus Monotis provide useful biochronologic indices for the Late Triassic (middle Norian–earliest Rhaetian). We report the succession of Monotis at Hernstein in Lower Austria where typical late Norian Monotis salinaria (Schlotheim) are overlain by strata with apparently the youngest Monotis known of demonstrable Rhaetian age: Monotis hoernesi Kittl and Monotis rhaetica sp. nov., a species closely related to M. rudis Gemmellaro. A Rhaetian (Sevatian 2) age is confirmed by the co‐occurrence of Monotis with the platform conodont Misikella posthernsteini and close association with the ammonoid Paracochloceras. A review of late Norian monotid species indicates that a profound extinction event occurred in the pelagic realm at or close to the Norian/Rhaetian boundary where c. 15 monotids (Monotis s.l. and Maorimonotis) became extinct. The surviving Monotis are dwarfed when compared to their Norian predecessors and may represent an ecological/phylogenetic response to the crisis.
Conformational Flexibility in Protein Function: Dynamics of S100A4, Photosynthetic Reaction Centre and the Prenylating Enzymes UbiA and MenA

Proteins are the most versatile macromolecules and they are essentially involved in the biological processes throughout all living organisms. The three dimensional structure of proteins and their dynamical properties underlie their biological function and knowledge about protein structure and dynamics contributes to a detailed understanding of biochemical processes. In this work various structural and dynamical methods were applied in the investigation of different protein systems, and in addition the stabilization of two membrane proteins for structural studies was explored. The first X-ray structure of human S100A4 in complex with a non-muscle myosin IIA (NMIIA) fragment was solved to 1. 9Å and contributed to our understanding in the structural mechanism of S100A4 mediated filament assembly which is believed to promote metastasis. The X-ray structure shows that the binding mechanism differs from that of other S100 proteins and that S100A4 adapts its conformation to the chemical properties of the ligand. Further studies on a C-terminal deletion mutant of S100A4 with combined structural high and low resolution methods unveiled a role of the conformational flexible C-terminus in the Ca 2+ -affinity to S100A4. The results suggest that the reduced metastasis properties that were previously observed in Cterminal deletions mutants of S100A4 might be due to an impaired Ca 2+ -control. The nature and the extent of conformational dynamics in photosynthetic reaction centers during the electron transport processes are still not well understood. Differences in the THz absorption spectra of photosynthetic reaction centre from Rhodobacter sphaeroides were measured upon light activation and indicate a change in molecular vibrations that occur most probably in LM subunit and are independent of the environment. Conformational flexible regions influence the formation of protein crystals for structural studies negatively and the structural stabilization of proteins is often applied in protein crystallization. A library of the polyprenyltransfeases UbiA and MenA with rational stabilized, predicted exposed surfaces was produced and eight mutants and the wild type proteins were recombinant overexpressed and purified. Homology models indicate that the mutations of potent mutants are situated in regions that are involved in the formation of crystal contacts. However additional exploration of the buffer environment of UbiA and MenA is required in order to stabilize the proteins for further studies and crystallization.
Integrative Biology, an Organismic Biologist's Point of View1

Under conditions of social stability such as existed in an earlier and simpler era when there was little change from one generation to the next, it is reasonable to assume that there was a positive correlation between age and wisdom. Today the validity of that assumption seems tenuous, to say the least. Consider my situation. I am 85 years old. Clearly, I am an old scientist, and I am not sure that I have any scientific wisdom to communicate. My uncertainty is in part related to the dynamics of the scientific enterprise. Because of the success of the natural sciences and the technology derivative from them, for the past four or five centuries the human species has lived in a state of accelerating technological and cultural change. The rate of change has been particularly high for us scientists. Indeed, we live in a state of continuous intellectual revolution—and that is not an easy situation to which to adjust. As one of the elder members of the community of integrative biologists, I am overwhelmingly aware that during this continuing intellectual revolution, seniority is more likely to be correlated with obsolescence than with wisdom. However, despite the rapidity of scientific change, science is an intensely historical activity: every investigator stands on the shoulders of those who have preceded him or her. My thoughts may be old-fashioned, perhaps obsolete, and almost certainly they are platitudinous. Nevertheless, they may have some historical interest, because they represent the understanding of a person whose university education and scientific activity spans more than 60% of the Twentieth Century, a period of scientific expansion and intellectual change without precedent in human history. Most scientists, consciously or subconsciously, operate within a series of assumptions about the nature of their areas of professional concern. I can identify the assumptions that have been the basis of my view of biology. My confidence in them has been sufficient for me to treat them as if they were axioms. In retrospect, it is clear that they have shaped my interpretation of research data and sometimes guided my selection of research problems. Some of these assumptions, which have been axiomatic to me, may be platitudes to you. They reflect the fact that during a lifetime of studying the functional adaptations of organisms I have never been able to decide whether I was a student 1 From the Symposium Integrative Biology: A Symposium Honoring George A. Bartholomewpresented at the Annual Meeting of the Society for Integrative and Comparative Biology, 5‐9 January 2004, at New Orleans, Louisiana.
Ein Metamodell zur architekturorientierten Beschreibung komplexer Systeme

Zusammenfassung: Dieser Beitrag stellt einen Ansatz zur Beschreibung von Softwaresystemen vor, der insbesondere zur Erfassung der Architektur komplexer Systeme dient. Er zielt daher nicht auf die Darstellung von Programmstrukturen ab, sondern auf die Beschreibung von Systemmodellen, die der Mensch zu unterschiedlichsten Zeitpunkten der Softwareentwicklung erstellt. Er eignet sich zur Beschreibung sowohl ubergeordneter als auch realisierungsnaher Modelle und hat sich in einer Reihe industrieller und universitarer Projekte bewahrt. Der Ansatz ist nicht an einem bestimmten Programmierparadigma ausgerichtet, sondern an den Bedurfnissen des Menschen nach Anschaulichkeit. Trotzdem konnen technische Merkmale komplexer Systeme wie Verteilung, Nebenlaufigkeit, Transaktionen oder ein dynamisch veranderlicher Aufbau aus Komponenten gut erfasst werden. Der Schwerpunkt dieses Beitrags liegt nicht auf der verwendeten Notation, sondern der Diskussion des zugrunde liegenden begrifflichen Metamodells.