Miracle-dz/UniFAR-FTUs huggingface dataset:
Contraceptive use patterns across teens sexual relationships.

Although teen pregnancy and birth rates in the United States have been declining over the past decade teenagers still have high rates of unintended pregnancy and STIs. Among sexually experienced teens unintended pregnancies are the result of either contraceptive non-use or contraceptive failure. However minimal national-level research has assessed factors associated with contraceptive consistency within sexual relationships. Understanding patterns of contraceptive use among teens will help policymakers to develop strategies for preventing unintended pregnancies and STIs. Our project examines contraceptive use patterns across all sexual relationships teens report. Our primary goal is to enhance our understanding of the factors that influence teens choices regarding contraceptive use or non-use so that teens can become more consistent contraceptive users. Our specific research questions are: 1) What are the patterns of partner and relationship characteristics and contraceptive use and consistency across teens sexual relationships? ; and 2) What characteristics of teens current and previous sexual relationships and partners are associated with contraceptive use and consistency across teens relationships? We answer these questions using a nationally representative longitudinal sample of adolescents from the National Longitudinal Study of Adolescent Health. (excerpt)
Effects of Electromagnetic Fields over DNA of Hamsters with Implanted Graffi Tumor

Studies were conducted with model systems of bio influence (Drossinakis’ method) with electromagnetic (e.m.) fields and infrared thermal field (ITF) (Ignatov, Mosin, Niggli, Drossinakis, 2013). The purpose of research is to analyze effects over DNA. Analysis of effects over water and physiological saline is carried out in the report. Results are achieved with blood serum of hamsters and physiological processes in hamsters with tumors. The water analyses have been conducted with Nonequilibrium Energy Spectrum (NES) and Differential Nonequilibrium Energy Spectrum (DNES) methods (Antonov, 1992; Ignatov, 1998). Experiments were carried out about the influence on tumor cells of mice in water. Reduction of DNES spectrum according to the control sample of cells in healthy animals was observed. (Antonov, 1992). Reduction is also observed in DNES spectrum in blood serum of people having oncological diseases, compared to the one of healthy people (Ignatov, 2012). Such a reduction is most prevalent in (-0.1387 eV; 8.95 µm; 1117 cm -1 ). In research of the effects of e.m. fields in water and blood serum from hamsters the range is (-0.08 – -0.14 eV) (8.9 –15.5µm) (645–1129 cm -1 ). Research is conducted for the effects over Graffi tumor that was implanted in hamsters (Toshkova, Ignatov, Zvetkova, Ignatov, Gluhchev, Drossinakis, 2019). Studies are conducted with pH and oxidation redox potential (ORP) effects of e.m. fields over physiological saline (Gluhchev, Ignatov, Drossinakis, 2019). Keywords: Infrared thermal field (ITF), electromagnetic fields (e.m. fields), experimental Graffi solid tumor, energy spectrum, NES and DNES methods. DOI : 10.7176/JHMN/68-05 Publication date: November 30 th 2019
Fetal Massive Pericardial Effusion as a Sign of Bilateral Diaphragmatic Agenesis: A Case Report

Congenital diaphragmatic hernia (CDH) is an unusual fetal malformation that requires early diagnosis and treatment. Commonly, presentations are in the left side (85%), followed by right (13%) and only very few (2%) bilateral. The last one is a severe condition associated with high mortality rates, and very rarely these cases survive for surgical treatment. We describe the case of a 34-week male fetus with pericardial effusion in transabdominal ultrasound. Pericardiocentesis was performed, and the presence of liver was noticed at the thoracic cavity, confirming a diaphragmatic hernia. The newborn presented acute respiratory distress and died 1 hour after birth. Necropsy revealed complete diaphragmatic agenesis, pulmonary hypoplasia, and incomplete intestinal malrotation. Survival of these patients depends on cardiopulmonary function. Bilateral agenesis of the diaphragm associated with incomplete intestinal malrotation is a rare entity, and its significance requires further research.
Smokeless tobacco and public health : a global perspective

Smokeless Tobacco and Public Health: A Global Perspective is the product of 3 years of effort involving 32 contributing authors and dozens of expert reviewers from around the world. This report presents information compiled from a wide range of data sources, including the Global Tobacco Surveillance System, some of which is being reported for the first time. An accompanying series of factsheets describes the characteristics and use of specific ST products and gives an indication of the wide variety and complexity of the ST product landscape. Chapter Topics
VANET-Based Volunteer Computing (VBVC): A Computational Paradigm for Future Autonomous Vehicles

Despite the surge in a vehicular ad-hoc network (VANET) and volunteer computing research, future high-end vehicles are expected to under-utilize the onboard computation, storage and communication resources. Therefore, this research envisions the next paradigm shift by merging VANET and volunteer computing, which we call VANET based volunteer computing (or VBVC). To date, the potential design system for VBVC has not been characterized. To fill up this gap, we first set forth the scientific classification of VBVC, which uses the automobiles alongside roadside units (RSU) to give computational administrations to different vehicles on the road. We propose a potential framework for different VBVC scenarios. Moreover, we provide an experimental evaluation of VBVC by comparing it with the traditional model in terms of job completion, latency, and throughput. The proposed VBVC performs better when compared with traditional approaches.
Cancer Predisposition Sequencing Reporter (CPSR): a flexible variant report engine for high-throughput germline screening in cancer

The value of high-throughput germline genetic testing is increasingly recognized in clinical cancer care. Disease-associated germline variants in cancer patients are important for risk management and surveillance, surgical decisions, and can also have major implications for treatment strategies since many are in DNA repair genes. With the increasing availability of high-throughput DNA sequencing in cancer clinics and research, there is thus a need to provide clinically oriented sequencing reports for germline variants and their potential therapeutic relevance on a per-patient basis. To meet this need we have developed the Cancer Predisposition Sequencing Reporter (CPSR), an open-source computational workflow that generates a structured report of germline variants identified in known cancer predisposition genes, highlighting markers of therapeutic, prognostic, and diagnostic relevance. A fully automated variant classification procedure based on more than 30 refined ACMG criteria represents an integral part of the workflow. Importantly, the set of cancer predisposition genes profiled in the report can be flexibly chosen from more than 40 virtual gene panels established by scientific experts, enabling customization of the report for different screening purposes and clinical contexts. The report can be configured to also list actionable secondary variant findings as recommended by ACMG, as well as the status of low-risk variants from genome-wide association studies in cancer. CPSR demonstrates superior sensitivity and comparable specificity for the detection of pathogenic variants when compared to existing algorithms. Technically, the tool is implemented in Python/R, and is freely available through Docker technology. Source code, documentation, example reports, and installation instructions are accessible via the project GitHub page: https://github.com/sigven/cpsr.
Psychiatry in the USA: an overview

The USA has the world’s largest economy and the highest per capita spending on healthcare, but it lags behind other countries on a number of key health measures. It ranks 23rd in healthy life expectancy and 32nd in infant mortality (World Health Organization, 2009). In 2000, the World Health Organization ranked the US healthcare system as 1st in responsiveness, 37th in overall performance, and 72nd by overall level of health (among 191 member nations in the study).
Santri’s Community in Political Change: Historical Interpretive

This study seeks to understanding the historical context of the construction and position of of Santri’s community in Javanese society. Evidences from case study in an agrarian village in East Java proved that political change had potentially eroded the patrimonial system which embedded in this community. The analysis drawn from research findings which scattering the complexity of indigenous factors covering historical background, institutional change, cultural form and economical mode of production within society. Using morphogenetics approach coupled with ethnographical methods, this research found that patrimonial system in santri’s community as traditional Islam backbone has shifted. From being a closed patron-cliental relationship, now it becomes more open and diverse. This study contributes to explain political legitimacy in Islamic-based organization in Indonesian politics after the authoritarian New Order regime. Particularly to capture what happens in the micro-level political phenomenon. This study also reveals the neglected and critical phase in Indonesia democratic transition from below.
Proposal for a Protocol for Awake Fiberoptic Intubation in Adult with Dexmedetomidine

Many agents, including fentanyl, remifentanil, midazolam and propofol, have been reported to assist with AFOI. However, these agents can cause respiratory arrest, loss of or reduced (heart) function, especially when used in high doses, thus increasing the of low oxygen levels (hypoxemia), aspiration, low blood pressure (hypotension) or slow heart rate (bradycardia). Ideally, sedation should be administered by another anesthetist and its effects closely monitored. An awake, calm, alert patient will follow commands and can aid the intubator by taking deep breaths or protruding their tongue.
Continuous Acts of Creativity: Art Therapy Principles of Therapeutic Change

It is 1:30pm on a Friday and participants saunter up a few stairs from lunch to the room that I only just finished setting with a table cover and art supplies. For the next two hours, the multipurpose space in the drop-in center for runaway and homeless youth and young adults transforms into an open art therapy studio. I welcome back the regulars and introduce myself and art therapy to newcomers. Everyone settles in and reaches for art materials. The early chaos of people catching up with each other settles into focused creative activity interspersed with varied conversations on music, food, jobs, romance, as well as hopes, frustrations, stressors. I also begin to create art – perhaps a still life of the art supplies, portrait of a group member (with their permission), or response art. Throughout the group, I will do my best to facilitate a therapeutic process that meets the needs of each individual and the group as a whole. To manage the flow of therapy, Beutler, Forrester, Holt, and Stein (2013) note principles of therapeutic change. These empirically-tested psychotherapy interventions relate to various strategies, such as facilitating professional relationships by demonstrating empathy or developing a therapeutic contract by establishing clienttherapist role expectations. Even though there are common factors across the mental health disciplines, art therapists have particular considerations. For example, Schwarz, Snir, and Regev (2018) identify the necessity for intentionally selecting art materials, structuring sessions, and advancing creative process. The contributions to this issue offer research and practice to enhance understanding of principles of therapeutic change in art therapy.
Factors influencing prescription of CNS medications in different elderly populations

David Craig *, A. Peter Passmore , Ken J. Fullerton , Timothy R.O. Beringer , David H. Gilmore , Vivienne L.S. Crawford , Patricia M. McCaffrey , Anne Montgomery Factors influencing the use of neuroleptic and other CNS-acting medications (antidepressants and hypnotics/anxiolytics) were examined in different elderly populations (>65 years): long-stay care hospital subjects (n = 381), nursing home subjects (n = 1247), private residential home subjects (n = 321), statutory residential home subjects (n = 525), old age psychiatry facility subjects (n = 48), community dwellers (n = 97), in different geographical areas (urban n = 1223 and rural n = 1396). Neuroleptics were prescribed in 28% of the individuals, hypnotics/anxiolytics in 33% and antidepressants in 12%. Prescription of neuroleptics was significantly predicted by institutional placement (other than long-stay care hospital facility), lower cognitive function and rural geographical area. Age greater than 75 years and lower functional score (lower dependency) significantly decreased the likelihood of receipt of neuroleptics. Antidepressant use was significantly less likely in male subjects, patients with cognitive impairment and patients greater than 85 years. Institutional placement (other than long-stay care hospital facility and old age psychiatry facility) and rural locality predicted increased likelihood of antidepressant prescription. Institutional placement (other than long-stay care hospital facility) and geographical (rural) location were significant independent predictors of hypnotic/anxiolytic use. Prescription of hypnotic/anxiolytic drug class was significantly less likely in those individuals with lower cognitive status. In this representative elderly cohort, patient characteristics: age, sex, cognitive score, functional score, place of residence and geographical location markedly influenced drug utilisation.
How strategy comes to matter: Strategizing as the communicative materialization of matters of concern

This article contributes to the discursive and interactional study of strategizing by drawing attention to the communicative practices through which strategy progressively materializes itself. Drawing on the interactions between the partners and members of a community-based organization participating in a strategic planning exercise, our study reveals that communication plays a key role in the initial formulation of strategy, that is, in deciding which issues matter most for the organization. We identify four communicative practices through which concerns gradually become strategic: presentifying, substantiating, attributing, and crystallizing matters of concern. The article contributes to the strategy-as-practice tradition by proposing that communication materializes strategic concerns and that strategizing takes place through that materializing process.
Frequency of urinary incontinence with pelvic organ prolapse and associated factors.

Introduction : To determine the frequency of common types of urinary incontinence (UI) in women with pelvic organ prolapse (POP) attending Uro-gynaecology clinics at Aga Khan Hospital Karachi. METHODS: A total of 85 women attending the Uro-gynaecology clinics with symptoms of pelvic organ prolapse were included in a cross sectional survey RESULTS: Out of 85 women presented with pelvic organ prolapse, 61(71.7%) were aged above 50 years and 24(28.4%) below 50 year of age . The frequency of SUI was reported by 46(54.1%) women, 16(18.8%) women presented with UUI and 23(27.1%) with MUI. Large majority of women were postmenopausal(69%) , multiparous(71%), , and obese with a BMI >25 (69.4%). Thirty nine (46%) women had III grade of POP and 46( 54%) had SUI. Grade of POP was significantly associated with UI (SUI). Grade II POP was associated statistically significant with SUI [Adjusted Odd Ratio (AOR) 0.04; 95% CI: 0.004, 0.418; P value: 0.007]. The other factors like age ,parity and BMI were not found to be statistically significant in association with UI. CONCLUSION: Pelvic organ prolapse and urinary and incontinence are significant problems in developing countries . Both of these conditions badly impact quality of life of women . In our study only SUI was found to be significantly associated with increasing grades of POP.
Response to Aka : Supplementing extensive reading with bi- & multi-modal input

Aka (2019) conducted an important year-long large-scale study demonstrating that Japanese high school students who undertook extensive reading performed better than a control group who undertook grammatical instruction. Those showing the greatest gains were those of lower and intermediate proficiency. The students’ achievement was measured in terms of language knowledge and reading ability. Aka compared the achievement of a control group of 205 students with an experimental group of 200 students. Both groups had 6 English classes a week. The lessons common to both groups were 3 hours of intensive reading and 1 hour of listening. The difference was that the control group had an additional 2 hours of grammar instruction, whereas the experimental group had 2 hours of extensive reading. Aka stated that the purpose of the study was to investigate whether “reading skills would improve through extensive reading, rather than listening skills” (p. 6).
Estandarización de datos y priorización de algoritmos para un sistema de recomendación

Un sistema de recomendacion es un conjunto de herramientas y tecnicas de software que provee sugerencias al usuario de un sistema sobre cuales item le pueden ser de utilidad [1], [2]. Un negocio fisico ofrece al consumidor productos o servicios populares, ya que existen limitaciones de espacio que no le permiten presentar muchas opciones en un solo lugar. Por otro lado, los negocios en linea pueden poner a disposicion del consumidor cualquier cosa que exista, incluyendo articulos populares y poco populares. Este fenomeno, llamado The Long Tail, obliga a estos negocios a recomendar articulos personalizados a cada usuario [3] logrando asi una mayor cobertura del catalogo y una mejor experiencia a sus clientes. La implementacion y despliegue de un sistema de recomendacion puede implicar una inversion sustancial, es por esto que muchas empresas de comercio electronico prefieren externalizar los servicios de recomendacion [4]. Este tipo de implementaciones son llamadas recomendaciones como servicio. El desarrollo de estos servicios requiere definir aspectos como la captura y actualizacion de los datos de entrenamiento, la evaluacion, seleccion e hibridacion de algoritmos segun los datos disponibles y las interfaces para consumir el servicio [5]. Cada cliente, que requiere un sistema de recomendacion, tiene un conjunto de datos con caracteristicas especificas. Disenar una solucion para diferentes conjuntos de datos implica un proceso de preparacion y adaptacion a los algoritmos que se van a utilizar, esta etapa representa un esfuerzo significativo.En la literatura se encuentra una gran variedad de algoritmos de recomendacion, no todos presentan los mismos resultados para diferentes conjuntos de datos. Es una tarea importante seleccionar el algoritmo que mejores resultados ofrece segun las caracteristicas de los datos del cliente. Este trabajo propone un sistema de recomendacion que estandariza los conjuntos de datos y presenta un mecanismo que explora diferentes algoritmos, prioriza y selecciona el que mejor lo hace segun un conjunto de metricas definidas. Se implementa un prototipo del sistema propuesto y se prueba con tres conjuntos de datos diferentes. Se comprueba la estandarizacion de los datos de entrada para los formatos propuestos, permitiendo el uso de diferentes fuentes de datos. Tambien se usa el prototipo para entrenar, hibridar, evaluar y priorizar los algoritmos en cada conjunto de datos.
Design of a biosensor for direct visualisation of auxin

In plants, one of the most important regulative small molecules is indole-3-acetic acid (IAA) known as auxin. Its dynamic redistribution plays an essential role in virtually every aspect of plant life, ranging from cell shape and division to organogenesis and responses to light and gravity1,2. So far, the spatial and temporal distribution of auxin at cellular resolution could not be determined directly. Instead it has been inferred from visualisation of irreversible processes involving the endogenous auxin response machinery3-7. This detection system failed to record transient changes. Here we report on a genetically encoded biosensor for quantitative in vivo visualisation of auxin distributions. The sensor is based on the E. coli tryptophan repressor (TrpR)8 whose binding pocket was engineered for specific IAA binding and coupled to fluorescent proteins to employ FRET as readout. This sensor, unlike previous systems, enables direct monitoring of the fast uptake and clearance of auxin by individual cells in the plant as well as the graded spatial distribution along the root axis and its perturbation by transport inhibitors. Thus, our auxin sensor enables mapping of auxin concentrations at (sub)cellular resolution and their changes in time and space during plant life.
Evaluation of Different Root Canal Filling Methods in Primary Teeth

Meandros Med Dent J 2018;19:132-7 Öz Amaç: Süt dişleri kök kanallarının dolumu için kullanılan beş farklı metodun etkinliğinin dijital radyografi yöntemiyle karşılaştırılmasıdır. Gereç ve Yöntemler: Çalışmada kök rezorpsiyonu %25’ten fazla olmayan toplam 50 adet çekilmiş süt ön diş kullanıldı. Dişler, Mtwo® NiTi döner aletler kullanılarak standart bir apikal genişlik elde edilecek şekilde hazırlandı. Dişler rastgele 5 gruba ayrıldı: grup 1: Metapex® şırınga (kontrol); grup 2: Metapex® şırınga ve Endoaktivatör® (sonik aktivasyon); grup 3: Metapex® şırınga ve indirekt ultrasonik aktivasyon grup 4: Endodontik irrigasyon iğnesi; grup 5: Lentulo spiral. Kanalların fosfor plakla alınmış radyografik görüntüleri ile kanal dolgusunun uzunluğu (yetersiz, ideale yakın, ideal ve taşkın dolgu) ve kalitesi (boşlukların varlığı, lokalizasyonu ve toplam alanı) değerlendirildi. Veriler istatistiksel olarak KruskalWallis ve Bonferroni-düzeltmeli Mann-Whitney U testleri kullanılarak analiz edildi. Bulgular: Kök kanal dolumları hem uzunluk hem de kalite anlamında Objective: To compare the efficacy of 5 different methods for filling primary teeth root canals by digital radiography. Materials and Methods: A total of 50 extracted primary anterior teeth with no more than 25% root resorption were prepared using Mtwo® NiTi rotary instruments to a standard apical file size. Teeth were randomly divided into 5 groups, as follows according to the sealer application method. Group 1: Metapex® syringe (control); group 2: Metapex® syringe and Endoactivator® (sonic activation); group 3: Metapex® syringe and indirect ultrasonic activation; group 4: Endodontic irrigation needle; group 5: Lentulo spiral. Photostimulated phosphor radiographs of canals were evaluated for length of filling (underfilled, suboptimally filled, optimally filled, overfilled) and quality of filling (presence, localization and total sum of voids). Data was statistically analyzed using Kruskal-Wallis and Bonferroni-corrected MannWhitney U tests. Results: For the both length and the quality of the filling the worse results were seen in the endodontic irrigation needle group (group 4) (p<0.05). However, there were no significant differences between the other groups (p>0.05). Conclusion: Based on the results of this study apart from the endodontic irrigation needle group, all the tested methods could be used for obturation of primary teeth.