Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimization of Subarachanoid Block by Oral Pregabalin for Hysterectomy

Background: 80% of patients undergoing surgical procedures experience postoperative pain1 and requires adequate pain relief. Nowadays drugs like COX2 inhibitors and calcium channel modulators (Pregabalin and Gabapentin) are been increasingly used for postoperative pain management effectively. We conducted this study to find whether preoperative pregabalin has any effect in postoperative analgesic requirement in patients undergoing hysterectomy under spinal anaesthesia. Patients & Methods: This randomized, double-blind, placebo-controlled trial was conducted in 150 patients undergoing hysterectomy under spinal anaesthesia, divided in three groups - Group I (PO) - Control group, Group II (P150) received 150 mg pregabalin and Group III (P300) received 300 mg pregabalin. We used VAS for anxiety, Ramsay sedation scale and VAS for patient satisfaction regarding pain relief. Results: There was significant reduction in anxiety in groups P (150) and P (300) than placebo group P (0) during intraoperative and postoperative period than preoperative period. There was significant sedation seen in groups P (150) and P (300) than placebo group P (0). First rescue analgesia in group P (300) was202.42±6.77 and in group P (150) was176.38±4.80on average, group P (0) was131.38±5.15. Dizziness was 44.44% in group P (300), 36.11% in group P (150), and 19.44% in group P (0). Patient satisfaction was better in P (300) group than other two groups. Conclusions: Pregabalin being an oral drug which would be easy for the patients to take and also its prolongation of the neuraxial block helps in immediate postoperative analgesia and further reduction of other parentral analgesics. Pregabalin 150mg would be the optimal preemptive dose for hysterectomy under spinal anaesthesia.
Critical success factors of expatriation by Malaysian international corporations

Globalization is fuelling competition for international expansion. As firms movefrom creating newproducts and services to marketing, this effort requires increased expatriation to achieve global business goals. This study identifies critical success factors (CSF) relating to expatriation by Malaysian corporations operating internationally and identifies a number ofstrategies that can be adopted by these corporations to enhance their viability overseas. In addition, this study reviews current issues related to expatriation and identifies and ranks factors that contribute to the success or failure of expatriation by Malaysian corporations. Self-administered questionnaires were developed to collect the primary data, yielding a response rate of35.2 percent. The results indicate that most Malaysian manufacturers are involved in expatriation activities. The ability to work in international teams was identified and ranked as the most important factor in determining the effectiveness ofexpatriation. Language proficiency ranked next in importance. In addition, adaptability to the international assignment and expatriate sensitivity to cultural elements were considered important to the success or failure of an international assignment . Results support previous research with regard to the importance ofan effective expatriation selection process in order for a company s international expansion strategy to succeed.
Enabling Integrity for the Compressed Files in Cloud Server

Cloud computing has been envisioned as next-generation architecture of IT enterprise. Cloud computing is the internet based model which delivers computing services on demand. Cloud storage moves the users data to large data centers, which are remotely located and on which user does not have any control. Apart having more benefits, this unique feature of the cloud also poses many new security challenges which need to be clearly understood and resolved. The important concerns that need to be addressed in cloud computing is to assure the integrity of data i.e. correctness of his data in the cloud. In this paper we provide a scheme which gives a proof of data integrity in the cloud which the customer can employ to check the correctness of his data in the cloud. This proof can be done by both the cloud and the customer and can be incorporated in the Service level agreement (SLA). Here we are encrypting the hash values and providing the more security. This scheme ensures that the storage at the client side is minimal which will be beneficial for thin clients. Here the computational time is minimized by using integrity and encryption methodology on the data in cloud . It should be noted that this scheme applies only to archive storage data.
Efficacy, safety, and tolerability of herpes zoster vaccine in persons aged 50-59 years.

BACKGROUND Herpes zoster (HZ) adversely affects individuals aged 50-59, but vaccine efficacy has not been assessed in this population. This study was designed to determine the efficacy, safety, and tolerability of zoster vaccine for preventing HZ in persons aged 50-59 years. METHODS This was a randomized, double-blind, placebo-controlled study of 22 439 subjects aged 50-59 years conducted in North America and Europe. Subjects were given 1 dose of licensed zoster vaccine (ZV) (Zostavax; Merck) and followed for occurrence of HZ for ≥1 year (mean, 1.3 years) postvaccination until accrual of ≥96 confirmed HZ cases (as determined by testing lesions swabs for varicella zoster virus DNA by polymerase chain reaction). Subjects were followed for all adverse events (AEs) from day 1 to day 42 postvaccination and for serious AEs (SAEs) through day 182 postvaccination. RESULTS The ZV reduced the incidence of HZ (30 cases in vaccine group, 1.99/1000 person-years vs 99 cases in placebo group, 6.57/1000 person-years). Vaccine efficacy for preventing HZ was 69.8% (95% confidence interval, 54.1-80.6). AEs were reported by 72.8% of subjects in the ZV group and 41.5% in the placebo group, with the difference primarily due to higher rates of injection-site AEs and headache. The proportion of subjects reporting SAEs occurring within 42 days postvaccination (ZV, 0.6%; placebo, 0.5%) and 182 days postvaccination (ZV, 2.1%; placebo, 1.9%) was similar between groups. CONCLUSIONS In subjects aged 50-59 years, the ZV significantly reduced the incidence of HZ and was well tolerated. CLINICAL TRIALS REGISTRATION NCT00534248.
Parameter identification of an axial-flux induction machine by winding functions

In this paper the parameters of an axial-flux induction machine are determined. The parameters are part of equations describing the dynamic of the machine and hence required to develop a dynamic model based on the winding function theory. This theory is widely used to simulate faults in different radial-flux machines. Former articles all dealing just with radial-flux machines. Here the theory for axial-flux induction machines is introduced and applied for parameter determination. This paper will be useful to construct a model of axial-flux induction machines in a simulation environment like MATLAB/ SIMULINK.
The role of the Audit Committee and the Board of Director in mitigating the practice of earnings management: Evidence from Jordan

Recently, the audit committees and boards of directors have been considered to be corporate governance mechanisms that can play key roles in mitigating earnings management practices. This study? s purpose is to explore the impact of the board of directors (i.e., size, CEO duality, independence and financial expertise and knowledge) and the presence of an audit committee with earnings management practices in Jordanian firms. The study used the leverage ratio as a control variable. The sample covered industrial firms listed in the Amman Stock Exchange from the years 2014-2016. This study used multiple regression in determining if the board of directors and the audit committee affect earnings management practices. The study revealed that the presence of an audit committee negatively affected the earnings management practice in industrial Jordanian firms. This study suggested that characteristics of the board of directors, namely, independence and CEO duality, significantly influenced the practices of earnings management Furthermore, the findings indicate that separating the position of CEO and chairman along with more independent board members plays an increasingly important role in preventing earnings management practices by ensuring the effective monitoring of management. The study recommends extending such research to offer a more comprehensive awareness of earnings management in emerging capital markets using new variables of corporate governance.
The Activities of the Muscles around the Ankle Joint during Foot-gripping are Affected by the Angle of the Ankle

[Purpose] The purpose of this study was to determine the activities of the muscles around the ankle joint during foot gripping. [Subjects] The subjects of this study were 17 healthy females. [Methods] We measured the maximum voluntary contraction (MVC) activities of the soleus muscle, the medial head of the gastrocnemius muscle, and the tibialis anterior muscle, and calculated %IEMG during foot gripping in 3 different ankle joint positions: 10° of plantar flexion, 0°, and 10° of dorsiflexion. [Results] The maximal force of foot gripping achived by the crural muscles in any ankle position was 30–50% IMEG of the MVC. Repeated analysis of variance showed that the %IEMG was significantly lower in 10°of dorsiflexion than in the other 2 positions for all muscles. [Conclusion] These results suggested that the crural muscles help the ankle joint by co-contracting during foot gripping.
Compact Low-Loss Wideband Differential Bandpass Filter With High Common-Mode Suppression

Compact low-loss wideband differential bandpass filters are presented in this letter. The proposed filters are constructed by a pair of multilayer differential microstrip-slotline transitions (MDMSTs) and microstrip line resonators. Wideband common-mode suppression and low insertion loss can be easily achieved by employing the MDMSTs. Wideband differential-mode passband and sharp notched band can be obtained by combining the microstrip resonators at the middle and the two sides with the pair of MDMSTs, respectively. The demonstrated filters with a compact size of 24 mm × 12 mm (0.56λg × 0.28 λg) exhibits a fractional bandwidth of 115% centered at 4.25 GHz (f0) with minimum insertion loss of 0.43 and 20 dB common-mode suppression from 1 to 10 GHz (2.35 f0).
Leveraging Process Innovation with Business Analytics

Although recognized as increasingly relevant, the relationships between analytical orientation and process innovation are still unclear, specifically the role of analytical resources and capabilities in this association. This paper presents the results of empirical research conducted to investigate these complex links. The empirical data was drawn from 81 companies of different sectors in Brazil. Data analysis was mainly based on path analysis with structural equation modeling. The findings of this study indicate that analytical orientation can leverage process innovation. Moreover, information quality is somehow a more valuable resource to analytical orientation than information technology, and that analytical capabilities, especially analytical leadership, were proven to be more important to sustain analytical orientation than companies' analytical resources. Another important result, also with considerable repercussion in future research on the theme, was the predictive relevance of analytical capabilities for analytical orientation. This was much higher than the predictive relevance shown by analytical resources.
Estimating the dopant distribution in Ca-doped alpha-SiAlON: statistical HAADF-STEM analysis and large-scale atomic modeling

We investigated the dopant distribution in Ca-doped α -SiAlON by using high-angle annular dark-field scanning transmission electron microscopy and a multi-slice image simulation. Our results showed that the electron wave propagated by hopping to adjacent Si(Al) and N(O) columns. The image intensities of the Ca columns had wider dispersions than other columns. To estimate the Ca distribution in the bulk material, we performed a Monte Carlo atomic simulation of the α -SiAlON with Ca dopants. A model including a short-range Coulomb-like repulsive force between adjacent Ca atoms reproduced the dispersion of the intensity distribution of the Ca column in the experimental image.
Exporting Barriers Perceived by Manufacturing SMEs: Evidence from Emerging and Advanced Markets

This paper explores the exporting barriers perceived by the Saudi Arabian and Australian Small and Medium-Sized (SME) businesses considering (or engaged in) exporting within manufacturing. Currently there is a paucity of research comparing and examining exporting barriers and obstacles facing exporting Saudi Arabian and Australian SMEs within manufacturing settings. Moreover, this is one of the first examination of these barriers within these contexts (Saudi Arabia and Australia). A total of 35 interviews (21 interviews from Saudi Arabia and 14 Australian) with SMEs mangers/owners within manufacturing industries were completed. The results suggest that SMEs managers’ perceived a total of 19 exporting barriers, influence their exporting decision and commitment. We recommend the use of a large scale survey to clarify the appropriateness of the barriers identified in this study so as to arrive at more generalisable results. Keywords: exporting barriers, exporting SMEs, perceived risk, Saudi Arabia, Australia manufacturing. DOI : 10.7176/EJBM/11-12-17 Publication date : April 30 th 2019
Stabilization of simple mechanical systems subject to inequality constraints

The problem of stabilizing a contact configuration of a one-degree-of-freedom mechanical system subject to a single inequality constraint is considered. By means of Lyapunov techniques it is shown that a PD-like state feedback control law achieves exponential stability and BIBS stability of the desired equilibrium, for either elastic or inelastic impacts. Apart from the theoretical result, simulations and experiments confirm the satisfactory behaviour of the proposed control law.
IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.

Interleukin 7 (IL-7) is a common gamma chain receptor cytokine implicated in thymopoiesis and in peripheral expansion and survival of T lymphocytes. The safety and activity of recombinant human IL-7 (rhIL-7) administration were therefore examined in HIV-infected persons. In this prospective randomized placebo-controlled study, a single subcutaneous dose of rhIL-7 was well tolerated with biologic activity demonstrable at 3 microg/kg and a maximum tolerated dose of 30 microg/kg. Injection site reactions and transient elevations of liver function tests were the most notable side effects. Transient increases in plasma HIV-RNA levels were observed in 6 of 11 IL-7-treated patients. Recombinant hIL-7 induced CD4 and CD8 T cells to enter cell cycle; cell-cycle entry was also confirmed in antigen-specific CD8 T cells. Administration of rhIL-7 led to transient down-regulation of the IL-7 receptor alpha chain (CD127) in both CD4(+) and CD8(+) T cells. Single-dose rhIL-7 increased the numbers of circulating CD4(+) and CD8(+) T cells, predominantly of central memory phenotype. The frequency of CD4(+) T cells with a regulatory T-cell phenotype (CD25(high) CD127(low)) did not change after rhIL-7 administration. Thus, rhIL-7 has a biologic and toxicity profile suggesting a potential for therapeutic trials in HIV infection and other settings of lymphopenia. This clinical trial has been registered at http://www.clinicaltrials. gov under NCT0099671.
Anti‐inflammatory cytokine IL‐10 and T cell cytokine profile in periodontitis granulation tissue

Th2 cells are more abundant than Th1 cells in periodontitis lesions, but the relative importance of the Th1 and Th2 subsets in periodontal disease is not understood. In addition, the role of proinflammatory and anti‐inflammatory cytokines in this disease process is unclear. Biopsies were obtained from 10 patients with early onset periodontitis (EOP) and 10 patients with adult periodontitis (AP). From all of the patients in the AP group we were able to obtain and section the gingival tissue to serve as controls. We used polyclonal monospecific antibodies to detect cells expressing IL‐2, IL‐4, IL‐6, IL‐10 and IL‐15, tumour necrosis factor (TNF‐α) and interferon‐gamma (IFN‐γ) in formalin‐fixed, paraffin‐embedded sections of granulation tissue from periodontitis lesions. We also employed a series of oligonucleotide probes to detect cells expressing the cytokine transcripts in the same tissue biopsies. Cells that expressed IL‐4 or IL‐6 were more numerous than cells expressing either IL‐2 or IFN‐γ. Th2 cells were more numerous in EOP and AP tissues. IL‐15 substitutes for IL‐2 in a number of biological activities related to the Th1 immune response, and interestingly, in periodontal lesions the IL‐15‐expressing cells outnumbered IL‐2‐expressing cells, suggesting that this is the pattern of immune regulation by T cells in the periodontium. The functional balance in the T cell subsets detected by their cytokine profiles underlies the importance of the anti‐inflammatory mechanisms taking place in the diseased tissue. The numbers of inflammatory leucocytes that express the anti‐inflammatory cytokine IL‐10 are much more widely distributed than those that express the proinflammatory cytokines IL‐6 and TNF‐α. This study suggests that large numbers of infiltrating inflammatory cells as well as accessory cells are involved in the down‐regulation of the inflammatory and immune response in periodontitis.
The Global Protection of Personal Health Data

The workshop is an activity of the IMIA Working Group ‘Security in Health Information Systems’ (SiHIS). It is focused to the growing global problem: how to protect personal health data in today’s global eHealth and digital health environment. It will review available trust building mechanisms, security measures and privacy policies. Technology alone does not solve this complex problem and current protection policies and legislation are considered woefully inadequate. Among other trust building tools, certification and accreditation mechanisms are dis-cussed in detail and the workshop will determine their acceptance and quality. The need for further research and international collective action are discussed. This workshop provides an opportunity to address a critical growing problem and make pragmatic proposals for sustainable and effective solutions for global eHealth and digital health.
Effects of Dibutyryl Cyclic AMP on Na+, K+‐ATPase Activity and Intracellular Na+ and K+ in Primary Cultures of Astrocytes from DBA and C57 Mice

Summary: Effects of chronic treatment of dibutyryl cyclic AMP (db‐cyclic AMP) on Na+, K+‐ATPase activity in cell homogenates and intracellular N a f and K+ contents [(Na+)i and (K+)i] were studied in primary cultures of astrocytes derived from cerebral cortex of neonatal audiogenic seizure‐susceptible DBA and audiogenic seizure‐resistant C57 mice. Na+, K+‐ATPase activity in cell homogenates was greater and (Na+)i was less in DBA astrocytes than in C57 astrocytes. There was no difference in (K+)i between astrocytes from DBA and C57 mice. Addition of db‐cyclic AMP to the medium from day 14 to day 21 in culture (final concentration 0.25 mM) increased Na+, K+‐ATPase activity in cell homogenates and decreased (Na+)i, but had no significant effect on (K+)i in astrocytes from either DBA or C57 mice. Chronic treatment with db‐cyclic AMP altered cell growth. Protein and DNA content of cultured astrocytes from both DBA and C57 mice was decreased. DNA was more affected than protein. Modifying K+ and Na+ concentration in medium altered Na+, K+‐ATPase activity in cell homogenates as well as (Na+)i and (K+)i in cultured astrocytes of both DBA and C57 mice. Changes in (Na+)i and (K+)i at different K+ concentrations in medium paralleled those in Na+, K+‐ATPase activity in cell homogenates. Results indicate that the ability to transport Na+ across the cell membrane and the response of Na+, K+‐ATPase to db‐cyclic AMP and to the changes in K + in medium of cultured astrocytes from audiogenic seizure‐susceptible DBA mice are sufficient.
Working Paper: Is there a consistent pattern in benefit sanctions rates by Jobcentre Plus offices in Scotland?

Within the debate on labour market activation policies and the public discussion on unemployment benefit sanctions and their effectiveness in raising transition rates back to employment, increasing attention has been paid on the role of caseworkers in employment offices. Caseworkers’ behavioural decisions may be influenced by a combination of factors, such as available resources, personal characteristics and attitudes, which may lead to different sanction outcomes for unemployed people. This working paper aims to identify whether there are consistent patterns in benefit sanctions rates across local employment offices (i.e. Jobcentre Plus offices) in Scotland. I used data from official UK government statistics covering monthly counts of unemployment benefit claimants and adverse sanctions for 93 Jobcentre Plus offices, for the period between April 2004 and September 2015. In this working paper, I provide a descriptive account of Job Seeker’s Allowance (JSA) sanction rates and contrast trends before and after October 2012, the month which marked the introduction of a new JSA sanctioning regime, characterised by more severe and lengthened sanctions.
Relation between severity of anemia and erythropoietin titer in human beings.

Patients with severe hematologic disorders may have elevated erythropoietin titers in plasma or urine at higher hemoglobin concentrations than those associated with elevated titers in experimental animals or patients anemic as a result of simple blood loss. Patients with "primary" hematologic disease may have a measurable titer of erythropoietin in the plasma and urine at hemoglobin concentrations up to 8 Gm. /100 ml. , but patients with iron-deficiency anemia show elevated titers in the urine only with hemoglobin concentrations at or below 4 Gm. /100 ml. and in the plasma below 5 Gm. /100 ml. The abruptness with which the titer rises and the severity of the anemia required before measurable titers appear are similar in man and in rabbits, sheep and dogs. The fact that no measurable erythropoietin titer can be demonstrated when the hemoglobin concentration is well below that required for intense stimulation of erythropoiesis and the abruptness of the rise at hemoglobin concentration of 4 Gm. /100 ml. or less suggest that erythropoietin may not be an important factor in the control of erythropoiesis except in extreme circumstances. On the other hand, these facts may be explained more simply by the insensitivity of the assay methods used.