Miracle-dz/UniFAR-FTUs huggingface dataset:
Riemann-Liouville Fractional Calculus and Multiindex Dzrbashjan-Gelfond-Leontiev Differentiation and Integration with Multiindex Mittag-Leffler Function

—The multiindex Mittag-Lefﬂer (M-L) function and the multiindex Dzrbashjan-Gelfond-Leontiev (D-G-L) differentiation and integration play a very pivotal role in the theory and applications of generalized fractional calculus. The object of this paper is to investi-gate the relations that exist between the Riemann-Liouville fractional calculus and multiindex Dzrbashjan-Gelfond-Leontiev differentiation and integration with multiindex Mittag-Lefﬂer function.
Restoration of superficially damaged flexor tendons in synovial environment. An experimental ultrastructural study in rabbits.

Flexor tendon from the synovial sheath region of rabbits was resected and placed as a free body in a synovial knee joint recess. Structural changes of the surface of the graft caused by the instruments used to handle the tendon during the surgery (jewellers microforceps), was analysed by electron microscopy at various time intervals up to 6 weeks. The superficial coat of amorphous material, i.e. ground substance, on the surface of the tendon was dishevelled by the instruments. The injured areas were crowded with monocytes and macrophages during the first days. An increasing number of fibroblasts and mesothelial-like cells covered the damaged area in less than two weeks. The superficial coat of ground substance was not completely restored until after 3 weeks or more. The results obtained are discussed in relation to functional aspects.
HYPERSENSITIVITY TO LOCAL ANAESTHETICS - 6 FACTS AND 7 MYTHS

Local anaesthetics (LAs) are commonly used drugs. In spite of their widespread use, true hypersensitivity appears to be very infrequent. In fact most of the adverse reactions are due to pharmacological, toxic or vasovagal effects of LAs. Our review of the literature has shown that true allergy to LA is in fact exceptional. Skin tests for LA allergy, including skin-prick tests (SPT) and intradermal (ID) tests, have poor sensitivity and specificity. True LA allergy, when appropriate, has to be confirmed by challenge. Provocation challenge is safe and well tolerated. Amino-ester LA chemical structure
Electrode alignment of transverse tripoles using a percutaneous triple-lead approach in spinal cord stimulation

The aim of this modeling study is to determine the influence of electrode alignment of transverse tripoles on the paresthesia coverage of the pain area in spinal cord stimulation, using a percutaneous triple-lead approach. Transverse tripoles, comprising a central cathode and two lateral anodes, were modeled on the low-thoracic vertebral region (T10–T12) using percutaneous triple-lead configurations, with the center lead on the spinal cord midline. The triple leads were oriented both aligned and staggered. In the staggered configuration, the anodes were offset either caudally (caudally staggered) or rostrally (rostrally staggered) with respect to the midline cathode. The transverse tripolar field steering with the aligned and staggered configurations enabled the estimation of dorsal column fiber thresholds (IDC) and dorsal root fiber thresholds (IDR) at various anodal current ratios. IDC and IDR were considerably higher for the aligned transverse tripoles as compared to the staggered transverse tripoles. The aligned transverse tripoles facilitated deeper penetration into the medial dorsal columns (DCs). The staggered transverse tripoles always enabled broad and bilateral DC activation, at the expense of mediolateral steerability. The largest DC recruited area was obtained with the rostrally staggered transverse tripole. Transverse tripolar geometries, using percutaneous leads, allow for selective targeting of either medial or lateral DC fibers, if and only if the transverse tripole is aligned. Steering of anodal currents between the lateral leads of the staggered transverse tripoles cannot target medially confined populations of DC fibers in the spinal cord. An aligned transverse tripolar configuration is strongly recommended, because of its ability to provide more post-operative flexibility than other configurations.
The Significance of Teeth in Pollution Detection

The general population is experiencing lifelong exposure to old and new hazardous substances. By using data collected from a subject's own teeth, accuracy in determining the effects of exposure is assured since extrapolation is excluded. The establishment of a common tooth bank can provide means to integrate data from multiple sources. Comprehensive pollution information shared by the environmental, scientific and medical communities can lead to a more efficient approach to a worldwide problem.
Prototype design of a compact plug-in solar electric vehicle application for smart power management architecture

In this work, we are providing details about experimental Electric Vehicle prototype. The goal is to build an All Electric power-train prototype with multi power sources input, and an open computer based setup to test new power management architecture introduced in our previous work. The electrical and mechanical features of the prototype are detailed. However, connectivity and networking layers for PM algorithm are kept for phase 2 of the work.
Enhanced Activation of CD83‐Positive T Cells *

CD83 is a marker molecule for mature dendritic cells (DCs) but is also substantially expressed on activated T cells in humans and mice. Its function is unknown, but CD83 knockout mice show an impaired thymic maturation of CD4‐positive cells and soluble CD83 inhibits partially antigen‐specific responses in vitro pointing to a role of CD83 in the immune system. Here we show that CD83‐positive T cells produce strongly increased amounts of interferon‐γ and interleukin‐2. In contrast, constitutive expression of CD83 on DCs alters neither the activation of DCs following addition of lipopolysaccharide nor the ability to present antigenic peptides. Thus, the expression of CD83 on T cells has direct functional consequences for tuning the activation threshold.
Overrepresentation of the Fcgamma receptor type IIA R131/R131 genotype in caucasoid systemic lupus erythematosus patients with autoantibodies to C1q and glomerulonephritis.

OBJECTIVE To test the hypothesis that there is an association between the Fcgamma receptor type IIA (FcgammaRIIA)-H/R131 polymorphism and autoantibodies to the collagenous region (CLR) of C1q in patients with systemic lupus erythematosus (SLE). METHODS One hundred ninety-five Caucasoid lupus patients were studied. Anti-C1q(CLR) antibodies in serum were measured by enzyme-linked immunosorbent assay (ELISA) and FcgammaRIIA genotype analysis was performed by polymerase chain reaction. Immunoglobulin subclass of the autoantibodies was measured by ELISA. RESULTS Fifty-six patients were anti-C1q antibody positive, and Ig subclass analysis indicated a predominance of IgG2 anti-C1q antibodies. Analysis of the SLE population as a whole revealed no significant difference in the allele frequencies of R131 and H131 compared with controls. There was, however, a significantly increased frequency of the R131 allele both in the anti-C1q-positive subgroup of patients (chi2 = 7.66, P<0.01) and in the 71 patients with nephritis (chi2 = 7.76, P< 0.01), compared with controls. CONCLUSION FcgammaRIIA-R131 constitutes a heritable susceptibility factor for the development of SLE with manifestations in the kidney in Caucasoid patients. The close associations demonstrated between this FcgammaRII variant, antibodies to C1q(CLR), and glomerulonephritis may be due to a failure of clearance of the potentially pathogenic IgG2 autoantibody.
A two-stage combined control strategy for parallel operation of inverter

Conventional control strategies for parallel operation of inverters are mainly classified into two categories. One is based on interconnection line which transfers the active and reactive power of each inverter. However, once a fault occurs at the communication channel, the whole system must be shut down. The other prevalent approach is using droop control theory, which needs no communication mechanism but has a power sharing problem. In this paper, a two-stage combined control scheme is proposed to overcome the shortcomings of traditional methods. The classical interconnection-based controller is applied to share the active power accurately and reactive power is controlled by means of Q-ω droop controller in the first stage. In the second stage, all inverters switch to P-E droop control mode with introducing an adaptive virtual impedance. This method can achieve accurate active and reactive power sharing as well as high reliability. Experimental results are provided to verify the feasibility of the proposed method.
Switching personal income tax and social security contributions between Slovenia and the Federation of Bosnia and Herzegovina

Abstract This article examines policy switching between Slovenia and the Federation of Bosnia and Herzegovina (FBH). The idea behind it is that national microsimulation models can be used to apply Slovenian parameters to the FBH data, as established by the Personal Income Tax (PIT) Act and Social Security Contributions (SSC) Act. Accordingly, we introduce FBH parameters to Slovenian data. Along these lines, we investigate the effects on public finance systems with respect to revenues from PIT and SSC, average after-tax income, tax progressivity, income inequality, and the redistributive effect in each of these two countries, using the other country’s PIT and SSC solutions. This is the first fiscal comparison of Slovenia and the FBH, as well as the first policy switching analysis of the two countries.
Reading Disabilities in SLI and Dyslexia Result From Distinct Phonological Impairments

Children with specific language impairment (SLI) who show impaired phonological processing are at risk of developing reading disabilities, which raises the question of phonological impairment commonality between developmental dyslexia (DD) and SLI. In order to distinguish the failing phonological processes in SLI and DD, we investigated the different steps involved in speech processing going from perceptual discrimination through various aspects of phonological memory. Our results show that whereas the memory for sequence is likewise impaired in either disorder, children with SLI have to face additional impairment in phonological discrimination and short-term memory, which may account for even poorer phonological awareness than dyslexics'.
Stomatal conductance of lettuce grown under or exposed to different light qualities.

BACKGROUND AND AIMS The objective of this research was to examine the effects of differences in light spectrum on the stomatal conductance (Gs) and dry matter production of lettuce plants grown under a day/night cycle with different spectra, and also the effects on Gs of short-term exposure to different spectra. METHODS Lettuce (Lactuca sativa) plants were grown with 6 h dark and 18 h light under four different spectra, red-blue (RB), red-blue-green (RBG), green (GF) and white (CWF), and Gs and plant growth were measured. KEY RESULTS AND CONCLUSIONS Conductance of plants grown for 23 d under CWF rose rapidly on illumination to a maximum in the middle of the light period, then decreased again before the dark period when it was minimal. However, the maximum was smaller in plants grown under RB, RGB and GF. This demonstrates that spectral quality during growth affects the diurnal pattern of stomatal conductance. Although Gs was smaller in plants grown under RGB than CWF, dry mass accumulation was greater, suggesting that Gs did not limit carbon assimilation under these spectral conditions. Temporarily changing the spectral quality of the plants grown for 23 d under CWF, affected stomatal responses reversibly, confirming studies on epidermal strips. This study provides new information showing that Gs is responsive to spectral quality during growth and, in the short-term, is not directly coupled to dry matter accumulation.
The Leucine-rich Repeat Protein LRIG1 Is a Negative Regulator of ErbB Family Receptor Tyrosine Kinases*

The molecular mechanisms by which mammalian receptor tyrosine kinases are negatively regulated remain largely unexplored. Previous genetic and biochemical studies indicate that Kekkon-1, a transmembrane protein containing leucine-rich repeats and an immunoglobulin-like domain in its extracellular region, acts as a feedback negative regulator of epidermal growth factor (EGF) receptor signaling in Drosophila melanogaster development. Here we tested whether the related human LRIG1 (also called Lig-1) protein can act as a negative regulator of EGF receptor and its relatives, ErbB2, ErbB3, and ErbB4. We observed that in co-transfected 293T cells, LRIG1 forms a complex with each of the ErbB receptors independent of growth factor binding. We further observed that co-expression of LRIG1 with EGF receptor suppresses cellular receptor levels, shortens receptor half-life, and enhances ligand-stimulated receptor ubiquitination. Finally, we observed that co-expression of LRIG1 suppresses EGF-stimulated transformation of NIH3T3 fibroblasts and that the inducible expression of LRIG1 in PC3 prostate tumor cells suppresses EGF- and neuregulin-1-stimulated cell cycle progression. Our observations indicate that LRIG1 is a negative regulator of the ErbB family of receptor tyrosine kinases and suggest that LRIG1-mediated receptor ubiquitination and degradation may contribute to the suppression of ErbB receptor function.
The Effect of Glucose on the Release and Bioactivity of Exosomes From First Trimester Trophoblast Cells.

CONTEXT Hyperglycemia and hypoxia are risk factors of metabolic complication during pregnancy. The interactions between oxygen and glucose-sensing pathways that regulate exosome bioactivity from placental cells, however, have not been established. OBJECTIVE The aim of this study was to test the hypothesis that exosomal signaling by placental cells (defined as the number of exosomes released per unit time and their bioactivity) is responsive to extracellular glucose concentration. METHODS First-trimester primary trophoblast cells were incubated with D-glucose (5 mM or 25 mM) under 1%, 3%, or 8% O2 for 48 hours. Exosomes were isolated from cell-conditioned media by differential and buoyant density centrifugation. The total number of exosome vesicles was determined by quantifying immunoreactive exosomal CD63. The effect of exosomes on cytokine (granulocyte macrophage colony-stimulating factor, IL-2, IL-4, IL-6. IL-8, IL-10, interferon-γ, and TNF-α) release from endothelial cells was established by a protein solution array analysis. RESULTS Glucose (25 mM) significantly increased the release of exosomes from trophoblast cells at all oxygen tensions tested (by approximately 2-fold when compared with controls, P < .001). Exosomes (100 μg/mL exosomal protein) released from trophoblast cells significantly increased (P < .05) the release of all cytokines from human umbilical vein endothelial cells when compared with the control (ie, cells without exosomes), with the exception of IL-2 and IL-10 (P > .05). CONCLUSIONS The effects of high glucose on exosomes bioactivity may be recapitulated in vivo and is of clinical relevance in association with maternal insulin resistance (resulting in hyperglycemia) and preeclampsia (associated with placental insufficiency and hypoxia).
Estimated and predicted changes in the cat population of Australian households from 1979 to 2005.

OBJECTIVE To estimate and predict changes in the cat population of Australian households from 1979 to 2005. METHOD Telephone surveys were used to estimate Australia's total household cat population for each year from 1979 to 1999. A simple mathematical model based on population characteristics in 1995 was used to predict future population changes to 2005. Estimates and predictions for 1996 to 1999 were compared to validate the model. RESULTS Australia's household cat population increased steadily from 2.23 million in 1979 to peak at 3.24 million in 1988. Since then it has steadily declined to 2.60 million in 1999. The population size predicted from the mathematical model was similar to that from surveys for the years 1996 to 1999. It is predicted that the population will continue to decline to approximately 2.19 million in 2005. The proportion of Australian households owning cats fell from 31.1% in 1994 to 25.8% in 1999, while the average number of cats per cat-owning household remained relatively constant at 1.47. CONCLUSIONS Australia's household cat population is decreasing, falling by 19% between 1988, when it reached its peak, and 1999. This contrasts with the US where the population increased by 13.9% over the same period. The decline in Australia appears to be due to a decrease in the total number of cat-owning households rather than the number of cats per cat-owning household. It is likely that this trend will continue unless there is a change in household pet ownership preferences in the meantime.
A Study on Array Signal Estimation of Desired Target using New Method in Interference and Noise Spatial

In this paper, DOA estimation is an important research area in array signal processing. The performance of adaptive beamforming methods are known to degrade severly in the presence of uncertainty in the signal sight direction. We propose a novel adaptive beamforming with a Bayesian method. Bayesian method a posterior probability density DOA estimator has been shown to perform excellently. The proposed method is based on clear modeling of unknown in the desired signal array response, which provides sufficiently robustness to unknown in desired DOA, enhances the adaptive array system performance. Simulation results showed that the proposed method appear significantly better than performance as compared with general adaptive beamforming method.
Robotic melon harvesting

Intelligent sensing, planning, and control of a prototype robotic melon harvester is described. The robot consists of a Cartesian manipulator mounted on a mobile platform pulled by a tractor. Black and white image processing is used to detect and locate the melons. Incorporation of knowledge-based rules adapted to the specific melon variety reduces false detections. Task, motion and trajectory planning algorithms and their integration are described. The intelligent control system consists of a distributed blackboard system with autonomous modules for sensing, planning and control. Procedures for evaluating performance of the robot performing in an unstructured and changing environment are described. The robot was tested in the field on two different melon cultivars during two different seasons. Over 85% of the fruit were successfully detected and picked.
Analysing discourse relations in natural language: The case of space and time

Discourse relations are links between utterances and sentences or sentence parts. These can be implicit or explicit through markers such as because, before, but, etc. Thus, the causal discourse relation between the two clauses that is explicit in 'He fell because he stumbled over a stone' can be inferred in the sentence 'He stumbled over a stone and fell'. Much research in this field focuses on the range of ways in which these connections can be established and inferred by the recipient (or analyst). However, the use of such markers in discourse also shows how a speaker conceptualizes the relationships between various aspects of what they are saying. Whenever they occur in discourse, they are therefore reflections of the speakers' mind in this respect. In this tutorial, we will explore these effects by focusing on how speakers conceptualise and express relationships in time and space in discourse (Tenbrink, 2007). In the first half, we will discuss the linguistic options in this regard, and work out some principles for (and differences between) temporal and spatial relationships. In the second half, we will look at how these effects can be investigated by a systematic analysis of speakers' discourse produced under controlled circumstances. This includes a brief introduction to the methodology of Cognitive Discourse Analysis, with a focus on relationships between spatial and temporal elements in discourse.
Dielectric constants of ferroelectric PZT at THz frequencies

The complex dielectric constant of bulk ceramic ferroelectric PbZr0.4Ti0. 6O3 was measured in the range 0.2-2 THz using transmission time-domain spectroscopy. The material shows strong absorption and high refractive index with large dispersion. The results are compared to equivalent thin film data in the literature.
Bone mineral density in top level male athletes of different sports

The purpose of this study was to determine the influence of muscle strength, trainingspecific and anthropometric parameters on bone mineral density (BMD) in male top athletes of different sports in comparison to untrained controls. BMD was measured by dual energy X-ray absorptiometry in 173 males, aged 18 to 31 years. Of these, 104 were athletes (runners, n = 21; cyclists, n = 12; triathletes, n = 18), heavy athletes (HA, judo and wrestling, n = 28), and team sport athletes (TS, handball, soccer, basketball, volleyball, n = 25); 44 were unspecifically trained sport students (STU); and 25 were untrained controls (UT). Sport- and group-specific differences were found in anthropometric but not strength parameters. Marked sport- and group-specific differences were found for BMD at lumbar spine (LSP) and the femoral sites (FEM). Group-specific effects on BMD were clearest when calculating percentual differences between BMD of athletes and UT: In group I (HA, TS, and STU), BMD at LSP and FEM were significantly (p < .01) higher compared to UT; in group II (R and TRI), BMD at FEM but not at LSP was higher compared to UT (p <.01); and in group III (C), no BMD value was significantly different from UT. Multiple regression analysis revealed lean body mass to be the strongest predictor for BMD at LSP and FEM. We conclude that mechanical loads have strong effects on bone adaptation. Sport-specific and body region-specific effects have to be taken into account for evaluation of osteogenic effects of exercise. Particularly dynamic sports with short, high, and multidimensional loads have the strongest effects on bone formation, independent of training quantity.