Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of maternal ethnic–racial identity on children’s internalizing symptom trajectories

We investigate the impact of maternal ethnic–racial identity on child internalizing trajectories in immigrant and U.S.-born Latinx families. Data from N=1,076 Latinx mothers’ reports at child ages 1, 3, 5, and 9 years were used. For children of U.S.-born mothers, but not immigrant mothers, greater levels of maternal ethnic–racial identity were associated with lower levels of internalizing symptoms at age 3, yet attenuated decreases in internalizing symptoms over time. Thus, mother’s ethnic–racial identity was a protective factor for children at preschool age but became less protective through school age. Our results suggest that incorporating ethnic–racial identity elements, particularly for U.S.-born mothers of toddlers to preschoolers, may be an important consideration when designing interventions for Latinx families.
Human epidermal growth factor receptor 2 expression in gastric cancer patients treated with curative intent gastrectomy

Purpose: This study aimed to clarify the association between human epidermal growth factor receptor 2 (HER-2) status and the clinicopathologic factors of patients who underwent curative intent gastrectomy. Methods: From June 2011 to May 2015, curative intent gastrectomy was performed in 441 patients at Konyang University Hospital. Among them, we evaluated the HER-2 status in 113 patients. Data on clinicopathologic parameters such as age, sex, histological subtype, endoscopic Lauren classification, tumor location, size, presence of lymphovascular invasion, invasion depth, pathologic stage, HER-2 overexpression, recurrence and survival were obtained. In this study, pathological HER-2 intensity scores of 0, 1+, and 2+ were assumed to be negative, 3+ only was to be positive for overexpression. Results: In a total of 113 cases who underwent curative intent gastrectomy with HER-2 testing, 16 (14.2%) cases had positivity of HER-2 overexpression. HER-2 overexpression had significant associations with tumor stage (19.0% in I-IIIb vs. 2.9% in IIIc-IV, P=0.036). Survival analysis of HER2 overexpression has no significant difference. Conclusion: In this study, HER-2 overexpression rate was 14.2% and patient tumor stage had significant association with HER-2 overexpression.
Taphophobia and resurrection mania following left parietal stroke

ABSTRACT The paper describes a patient with psychotic depression following left inferior parietal stroke. He had a dominant delusion: a belief that he was buried alive and had died thereafter. This delusion was an amalgamation of taphophobia (fear of being buried alive) and Cotard’s nihilistic delusion. This taphophobia-Cotard complex was accompanied by a resurrection delusional belief that his son would resuscitate him by pressing his chest through the gravestone, during which the son’s hands would be detached from his body. This uncanny presentation is analyzed on various levels: Psychiatric level with an attempt to understand this presentation as reactivation of post-traumatic stress disorder; classical neurological level based on the function of the left parietal cortex and its role in body representations as in Gerstmann’s syndrome; Coltheart’s neuropsychological “Two-Factors Model” of delusional beliefs suggesting that the nihilistic-like delusion stems from false interpretation secondary to impaired mental activity that follows similar brain lesions and that this interpretation is not rejected due to lack of censorship activity; psychodynamic level – looking at the switch to primary thinking processes and at the accompanying uncanniness, anxiety and manic defenses. The paper suggests that what seems like diverse and haphazard presentation can be a multifaceted expression of the crucial function of the left inferior parietal cortex as a heteromodal cortex sited in an intersection between concrete perceptions and symbolic constructs and between primary and secondary thinking processes.
Experimental Acute Pancreatitis Models: History, Current Status, and Role in Translational Research

Acute pancreatitis is a potentially severe inflammatory disease that may be associated with a substantial morbidity and mortality. Currently there is no specific treatment for the disease, which indicates an ongoing demand for research into its pathogenesis and development of new therapeutic strategies. Due to the unpredictable course of acute pancreatitis and relatively concealed anatomical site in the retro-peritoneum, research on the human pancreas remains challenging. As a result, for over the last 100 years studies on the pathogenesis of this disease have heavily relied on animal models. This review aims to summarize different animal models of acute pancreatitis from the past to present and discuss their main characteristics and applications. It identifies key studies that have enhanced our current understanding of the pathogenesis of acute pancreatitis and highlights the instrumental role of animal models in translational research for developing novel therapies.
Systematic Journal Review on S & OP Publications and Avenues for Future Research to Support Smart Industries

This research paper attempts to highlight the scarcity of articles published in the field of Sales & Operations Planning (S& OP) in supply chain management. Literatures in leading journals are limited in the area of S & OP and there is a need to address this limitation to aid efforts to complement the demand planning process in smart industries. Â In 2010, it was recorded that only 15 papers were published and less than a handful of articles were written throughout the mid-2000s. Additionally, within these limited publications, topics have centered on structural components for operational processes rather than the demand planning or S & OP process. With the advent of big data, internet of things (IOT) and Industry 4.0, there is a need for more articles to be published to support full supply chain integration.
From Business Ideas To Successful Entrepreneurship

Under the current market conditions, business success is the vector that ensures sustainability and obtaining value for business stakeholders. In the field of entrepreneurship, the road to success, the experiences, knowledge and skills acquired by the entrepreneur are stimulating factors of the entrepreneurial spirit.The paper highlights the importance of benchmarking in the analysis of business success in order to identify business models in the online space that can be transformed into successful businesses. Starting from the comparative analysis of two giants in the field of online business, namely Amazon and Ebay, the authors concentrated the success factors identified for the two companies in a new business model for the online sales market.
Maternal and Infant Adiposity: Metabolic Health Related Consequences

markdownabstractObesity and excessive gestational weight gain may have several consequences for both mother and child. Infancy also seems to be critical for the development of obesity and cardiometabolic diseases. In this thesis, we examined the adiposity and cardiovascular health related consequences of maternal and infant adiposity. The research described in this thesis is part of the Generation R Study, Rotterdam, the Netherlands and the Generation XXI, Porto, Portugal. The findings of this thesis emphasize the importance of maternal adiposity during pregnancy and infant adiposity on the adiposity status and cardiovascular profile in later life. Prevention of maternal adiposity during pregnancy and infant adiposity is important to reduce the burden of obesity and cardiovascular disease throughout the life course and in future generations.
Investigating the Biological and Biochemical Consequences of Met Function and Dysfunction in Canine Osteosarcoma

ii Dedication . vii Acknowledgments. viii Vita . x List of Tables . xiv List of Figures . xv Introduction . 1 Met Structure and Function . 1 Met and Cancer . 3 Met and Canine OSA . 7 Summary . 9 Chapter 1: The Novel HSP90 Inhibitor STA-1474 Exhibits Biologic Activity Against OSA Cell Lines . 10 Abstract . 10. 10 Background . 11
Morphological and SSR marker characterization of wild and cultivated cowpeas (Vigna unguiculata L. Walp)

Three hundred and ninety accessions comprising 260 cultivated and 130 wild cowpea accessions were evaluated phenotypically using 27 cowpea descriptors. Morphological evaluation of some qualitative traits revealed 11.92% and 29.23% presence of pigmentation on the stem, 1.53% and 20.76% presence of stripes on the pod, and 0% and 20% presence of hairiness on the plant of cultivated and wild cowpeas respectively. As for the molecular analysis, sixteen SSR primers were employed for genotyping 48 accessions from both wild and cultivated cowpeas. The data generated a dendrogram with three clusters, two of which consisted of wild cowpea while the third cluster comprised all the cultivated cowpeas, including the yard-long-bean (Vigna unguiculata subsp. sesquipedalis) and Vigna unguiculata subsp. cylindrica accessions. Two wild accessions of subsp. dekindtiana, and one each of subsp. kgalagadensis and protracta clustered with cultivated cowpea indicating their relationships with cultivated cowpea, but not with other wild cowpeas. The numbers of polymorphic SSR bands in cultivated and wild cowpeas were 38 and 54, respectively, while the PIC values were 4.47 and 6.14, respectively, showing a greater genetic diversity in wild than in cultivated cowpeas. The subsp. dekindtiana had the highest number (80%) of shared SSR bands with cultivated cowpea followed by subsp. protracta with 54% of shared bands. Five species of wild cowpea have hairs and so could be used in breeding for resistance to insects.
Ultrasound and clinical findings in the metacarpophalangeal joint assessment of show jumping horses in training

Background Physical exercise is known to cause significant joint changes. Thus, monitoring joint behavior of athletic horses is essential in early disorders recognition, allowing the proper management. Objectives The aims of this study were to determine the morphological patterns, physical examination characteristics and ultrasound findings of show jumping horses in training and to establish a score-based examination model for physical and ultrasound follow-ups of metacarpophalangeal joint changes in these animals. Methods A total of 52 metacarpophalangeal joints from 26 horses who were initially in the taming stage were evaluated, and the horses' athletic progression was monitored. The horses were evaluated by a physical examination and by B-mode and Doppler-mode ultrasound examinations, starting at time zero (T0), which occurred concomitantly with the beginning of training, and every 3 months thereafter for a follow-up period of 18 months. Results The standardized examination model revealed an increase in the maximum joint flexion angles and higher scores on the physical and ultrasound examinations after scoring was performed by predefined assessment tools, especially between 3 and 6 months of evaluation, which was immediately after the horses started more intense training. The lameness score and the ultrasound examination score were slightly higher at the end of the study. Conclusions The observed results were probably caused by the implementation of a training regimen and joint adaptation to physical conditioning. The joints most likely undergo a pre-osteoarthritic period due to work overload, which can manifest in a consistent or adaptive manner, as observed during this study. Thus, continuous monitoring of young athlete horses by physical and ultrasound examinations that can be scored is essential.
Current evidence and outcomes for retinopathy of prematurity prevention: insight into novel maternal and placental contributions

Retinopathy of prematurity (ROP) is a blinding morbidity of preterm infants, which represents a significant clinical problem, accounting for up to 40% of all childhood blindness. ROP displays a range of severity, though even mild disease may result in life-long visual impairment. This is complicated by the fact that our current treatments have significant ocular and potentially systemic effects. Therefore, disease prevention is desperately needed to mitigate the life-long deleterious effects of ROP for preterm infants. Although ROP demonstrates a delayed onset of retinal disease following preterm birth, representing a potential window for prevention, we have been unable to sufficiently alter the natural disease course and meaningfully prevent ROP. Prevention therapeutics requires knowledge of early ROP molecular changes and risk, occurring prior to clinical retinal disease. While we still have an incomplete understanding of these disease mechanisms, emerging data integrating contributions of maternal/placental pathobiology with ROP are poised to inform novel approaches to prevention. Herein, we review the molecular basis for current prevention strategies and the clinical outcomes of these interventions. We also discuss how insights into early ROP pathophysiology may be gained by a better understanding of maternal and placental factors playing a role in preterm birth.
The importance both of early diagnosis and smoking cessation in the battle against lung cancer

J Thorac Dis 2020;12(7):3813-3814 | http://dx.doi. org/10.21037/jtd.2020. 02.18 The importance both of early diagnosis and smoking cessation to reduce the incidence and mortality of lung cancer (LC) is highlighted in this special issue of Journal of Thoracic Disease with a selection of articles written by a panel of eminent experts. Screening programs are fundamental to detect early LC and to reduce the mortality rate, as demonstrated by several randomized trials with low-dose computed tomography (LDCT) in high-risk subjects (1-3). However, although LDCT screening is already available in some countries, its large-scale implementation has not yet taken place. Since 1950 Wynder and Graham in their study published in the Journal of the American Medical Association (now known as JAMA) reported the correlation between tobacco smoking and LC (4). Tobacco smoking is a leading cause not only of LC but also of cardiovascular diseases. The magnitude of the problem has forced many nations to formulate public policies related to tobacco usage with the aim to encourage smokers to stop smoking, to discourage non-smokers from starting and to protect non-smokers from the effects of passive smoking. However, the number of smokers is declining only in developed countries, while in the rest of the world the number of smokers is increasing. As recently reported, in USA the continuous decrease in LC cancer mortality is mainly due to smoking reduction interventions, as well as to advances in LC treatment; moreover, LC incidence declines twice as fast in men as in women, reflecting differences in tobacco uptake and cessation between males and females (5). In conclusion, implementation of screening programmes, tobacco control policies, new smoking cessation methods, as well as advances in diagnosis and treatment, represent the best strategy to transform LC in a preventable and a curable disease.
Localization of Acoustically Tagged Marine Animals in Under-Ranked Conditions

A key technology in the movement tracking of marine animals is localization using acoustic transmitters. These are attached to marine animals and are detected by an array of receivers. Then, offline localization is performed by multilateration. However, due to the transmitter's low power and environmental conditions, emissions may be detected by only a limited number of receivers, causing localization ambiguities to arise. This work proposes a solution for such localization ambiguities. The proposed method assumes that the position of acoustically-tagged marine animals follows a hidden Markov model, such that localization ambiguities can probabilistically be resolved using a Forward-Backward algorithm. Our method is able to extrapolate the positions in a data series, as long as one sample in that series is picked up by three receivers, or if the identity of the receivers changes during tracking. Performance analysis shows that the localization accuracy of our method approaches the Cramér-Rao lower bound. Furthermore, to demonstrate the suitability of our method in a real sea environment, we have established a testbed that operated for three months, demonstrating localization of 20 acoustically-tagged sandbar sharks. Compared to the available solutions, roughly 20 times more location estimates were made; thereby, significantly increasing the impact of the test-site.
The spasticity in the motor and functional disability in adults with post-stroke hemiparetic

Introduction: Spasticity acts as a limiting factor in motor and functional recovery after Stroke, impairing the performance of daily living activities. Objective: To analyze the influence of spasticity on main muscle groups and to associate it with motor impairment and functional level of chronic hemiparetic patients after stroke. Methods: Twenty-seven chronic hemiparetic patients of both sexes were selected at the Physical Therapy and Occupational Therapy Service of the Unicamp Clinics Hospital. Assessments were carried out in two sessions, in the first one the motor impairment (Fugl-Meyer Assessment - FM) and functional impairment (Barthel Index - BI) were evaluated, and in the second, the degree of spasticity of the main muscle groups (Modified Ashworth Scale - MAS). Results: A negative correlation was detected between upper limb spasticity and motor and functional impairment. No muscle group evaluated in the lower limbs showed correlation between muscle tone and the level of impairment of the lower extremity on FM and the functional level measured by BI. Conclusion: Spasticity has been shown to be a negative influence factor in the level of motor and functional impairment of the upper limbs of chronic hemiparetic patients after stroke.
The Jacobians of matrix transformation about singular random matrices and its applications

Abstract In this paper, we give the Jacobians of matrix transformations and when the constant matrices A and are singular rectangular matrices, not limited to square matrices, and the random variables in the random matrices X, Y can be linearly dependent, W and are singular random matrices. Furthermore, some important properties about singular multivariate Normal distribution and singular Wishart distribution are proved by using these Jacobians. Finally, the density function of and the distribution of generalized Hotelling’s T 2 statistic are obtained.
Colonização por staphylococcus aureus em mucosa nasal de idosos do Lar Maria Tereza Vieira de Londrina

Staphylococcus aureus e uma especie bacteriana Gram-positiva que apresenta - se como um microrganismo comensal ou patogenico e pode ser isolada, principalmente, das narinas e de fossas nasais de seres humanos saudaveis. O uso indiscriminado de antimicrobianos nos ultimos 50 anos tem levado a selecao de cepas multirresistentes, um crescente problema de saude publica, destacando S. aureus resistente a meticilina, MRSA, devido a possibilidade de falha terapeutica com antimicrobianos beta lactâmicos nestes casos. Este estudo tem como objetivo avaliar a colonizacao nasal por S. aureus em idosos do Lar Maria Teresa Vieira de Londrina, realizar a demonstracao dos perfis de sensibilidade aos antimicrobianos destas amostras e relacionar com os fatores: sexo, infeccao e internacao recentes. Os indices de colonizacao encontrados foram de 45% para S. aureus e de 5% para MRSA. Duas das 3 amostras MRSA tambem apresentaram resistencia ao ciprofloxacino, eritromicina e clindamicina e foram isoladas de pacientes com historico de internacao e infeccoes recentes. Os resultados encontrados neste estudo demonstraram prevalencias de colonizacao nasal da populacao analisada, tanto para S. aureus, quanto para MRSA em porcentagens comparaveis com outros estudos realizados. No entanto, a proximidade entre os individuos institucionalizados e a manipulacao por cuidadores em comum pode levar a disseminacao das cepas MRSA, representando riscos para estes pacientes idosos, que apresentam riscos aumentados de desenvolver infeccoes devido a fatores proprios da senescencia.
Ellipsoidal Luneburg Lens Binary Array for Wide-Angle Scanning

An ellipsoidal Luneburg lens (LBL) binary array is proposed and implemented for wide-angle scanning. In order to solve the occlusion problem between the lens elements in the array, the spherical LBL is transformed into the ellipsoidal LBL based on the transformation optics. The permittivity distribution of the LBL is revised to increase the lens’ aperture efficiency when the lens is not particularly large compared with the feed. Further, by introducing the local-beam shifting method, the number of feeds under each lens and the mutual coupling between the feeds can be reduced with the scanning characteristics remained. To validate the proposed design, a ${1 \times 2}$ ellipsoidal LBL array has been designed, fabricated, and tested. Each ellipsoidal LBL with 110 mm long-axis radius and 88 mm short-axis radius is fabricated by means of 3-D printing technology. Patch antennas operating at 2.25 GHz are employed as feeds. The measured results show that the proposed ellipsoidal LBL binary array can realize the maximum gain of 15.5 dB at zenith direction and 13.3 dB at 62°. The maximum scanning angle of ±68° can be achieved with a 3 dB gain reduction and −8 dB sidelobe.
Bladder reinnervation by nerve transfer using a primarily motor donor nerve (femoral nerve branches) induces increased sympathetic bladder innervation

Hypothesis / aims of study Preganglionic sympathetic axons to the pelvic viscera originate from lumbar neurons and contribute to both the sympathetic chain ganglia coursing the vertebral column length and the caudal (inferior) mesenteric ganglia. Postganglionic sympathetic axons to the urinary bladder originate mostly from L7-S2 sympathetic ganglia and the caudal (inferior) mesenteric ganglion (1,2). We tested the hypothesis that after bladder decentralization and transfer of a lumbar originating somatic nerve (motor branches of the femoral nerve) that postganglionic sympathetic axons will sprout from intact ganglia to reinnervate pelvic viscera, such as the urinary bladder. We also tested whether this surgery induces a similar increased sympathetic innervation of the external urethra sphincter and clitoris.
Key supplier retention for electrical and electronic industry: determinant factors

The purpose of this article is to identify the possible determinant factors influencing key supplier retention in electric and electronics industry. The data were collected from purchasing and sales managers working for electric and electronic companies in Malaysia. A total of 112 usable responses were received from various electric and electronics firms. The findings reveal that besides the four pure predictors namely supplier engagement, supplier quality, supplier infrastructure, supplier commitment which influences supplier retention, confidential sharing is a new determinant emerged for key supplier retention, has a significant positive relationship. The present paper provides guidance for suppliers who are offering services to the electric and electronic industry to focus and implement on the determinants factors of key supplier retention to effectively sustain as the preferred supplier for their manufacturing companies. However, the findings from this study nature only the context of Malaysian electrical and electronic industry for key supplier retention.