Miracle-dz/UniFAR-FTUs huggingface dataset:
PENGARUH PENERAPAN SISTEM AKUNTANSI PEMERINTAH DAERAH, PEMAHAMAN AKUNTANSI, DAN KETAATAN PADA PERATURAN PERUNDANGAN TERHADAP AKUNTABILITAS KINERJA INSTANSI PEMERINTAH (Studi Pada Satuan Kerja Perangkat Daerah Kota Pekanbaru)

This study aims to determine the effect of implementation local government accounting system, the understanding of accounting, and the adherence of the law regulation on the performance accountability of goverment institution. Population and sample in this study was SKPD the city of Pekanbaru. Collecting data using primary data collection, the questionnaires by using sensus technique. This study used multiple linier regression analysis techniques. The results of this study were : 1). Implementation of local government accounting system positive effect on the performance accountability goverment institution. 2). Understanding of accounting has a positive effect on the performance accountability goverment institution. 3). The adherence of the law regulation positive effect on the performance accountability goverment institution. Keywords: performance accountability, accounting system, the adherence, and the law regulation.
Standardized Observational Assessment of Attention Deficit Hyperactivity Disorder Combined and Predominantly Inattentive Subtypes. II. Classroom Observations

Abstract. Trained classroom observers used the Direct Observation Form (DOF; McConaughy & Achenbach, 2009) to rate observations of 163 6- to 11-year-old children in their school classrooms. Participants were assigned to four groups based on a parent diagnostic interview and parent and teacher rating scales: Attention Deficit Hyperactivity Disorder (ADHD)—Combined type (n = 64); ADHD—Inattentive type (n = 22); clinically referred without ADHD (n = 51); and nonreferred control children (n = 26). The ADHD—Combined group scored significantly higher than the referred without ADHD group and controls on the DOF Intrusive and Oppositional syndromes, Attention Deficit Hyperactivity Problems scale, Hyperactivity-Impulsivity subscale, and Total Problems; and significantly lower on the DOF On-Task score. The ADHD—Inattentive group scored significantly higher than controls on the DOF Sluggish Cognitive Tempo and Attention Problems syndromes, Inattention subscale, and Total Problems; and significantly lower on the DOF On-Task score. Implications are discussed regarding the discriminative validity of standardized classroom observations for identifying children with ADHD and differentiating between the two ADHD subtypes.
Problems for Credulism

I’ve defended views about the epistemology of perception that I call “dogmatist. ” They are close to views defended by Michael Huemer and John Pollock, and somewhat more broadly to a range of views defended by others. These views have been criticized for being incompatible with Bayesianism. I will take Roger White’s “Problems for Dogmatism” (White 2006) as representing these criticisms. This essay will review and assess some central pieces of the criticisms. Doing so will reveal some limits of Bayesianism when it comes to representing undermining evidence.
Neutral super-oxidised solutions are effective in killing P. aeruginosa biofilms

Bacteria growing in biofilms can become up to 1000-fold more resistant to antibiotics and biocides as compared to their planktonic counterparts. As a result of this increased resistance, biofilms and biofilm-related infections cannot be effectively treated with conventional antibiotic therapy. The goal of this study was to determine the efficacy of three neutral pH, super-oxidised solutions (nSOSs, OIS-80, OIS-125, OIS-200, Microcyn Technology) varying in oxychlorine concentration (80, 125 and 200 ppm) against P. aeruginosa grown planktonically and as biofilms. Exposure for 20 s of exponential phase cells to any of the three solutions was sufficient to reduce viability by more than five logs. However, only exposure for 10 min to OIS-125 and OIS-200 for 10 min was sufficient to eradicate stationary phase P. aeruginosa cells. The efficacy of nSOSs on P. aeruginosa biofilms, grown to maturity in continuous flow tube reactors, was determined upon treatment up to 60 min. Viability pre- and post-treatment was determined by CFU counts. The effect of these solutions on P. aeruginosa biofilms and biofilm architecture was further visualised by confocal scanning laser microscopy and quantitatively analysed by COMSTAT. Under these experimental conditions, only OIS-125 and OIS-200 achieved a >3-log reduction and biofilm disaggregation within 30 min of exposure. Because OIS-125 and OIS-200 enhance the disaggregation of biofilms, their use in the treatment of surface-related biofilm infections deserves further investigation.
Acquiring basic word order: evidence for data-driven learning of syntactic structure

Recent studies indicate that young English-speaking children do not have a general understanding of the significance of SVO order in reversible sentences; that is, they seem to rely on verb-specific formulas (e.g. NPpusher – form of the verb PUSH – NPpushee) to interpret such sentences (Akhtar & Tomasello, 1997). This finding raises the possibility that young children may be open to learning non-SVO structures with novel transitive verbs. To test this hypothesis, 12 children in each of three age groups (two-year-olds, three-year-olds, and four-year-olds) were taught novel verbs, one in each of three sentence positions: medial (SVO), final (SOV), and initial (VSO). The younger age groups were equally likely to use the novel (non-English) orders spontaneously as to correct them to SVO order, whereas the oldest children consistently corrected these structures to SVO order. These results suggest that English-speaking children's acquisition of a truly general understanding of SVO order may be a gradual process involving generalization (learning) from examples. The findings are discussed in terms of recent data-driven learning accounts of grammar acquisition.
The role of blink adaptation in the pathophysiology of benign essential blepharospasm.

OBJECTIVE To investigate eyelid movements in patients with benign essential blepharospasm (BEB), with an emphasis on the characterization of the kinematics of normal and spastic blinks, assessment of interocular differences, and further delineation of the role of adaptive blink mechanisms in eyelid movement disorders. PATIENTS AND METHODS The electromagnetic search coil technique was used to record the metrics of blinks bilaterally in 5 patients with untreated BEB. Eyelid kinematics and the main-sequence (peak velocity vs amplitude) relationships were analyzed. RESULTS Patients with BEB exhibited a decrease in blink amplitude and peak velocity. Moreover, the main-sequence slope was decreased bilaterally. Spasms were bilateral and relatively conjugate. There was no change in the coordination of normal blinking across the 2 eyelids. CONCLUSIONS These data demonstrate the operation of the adaptive regulation of blinking in an eyelid movement disorder. The findings suggest that the adaptive regulation of blink is a bilateral event. Blink-adaptive control systems can act on the blink reflex excitability and main-sequence relationships, changing these either together or independently. The hyperexcitable blink reflex of BEB is met by what is believed to be an adaptive decrease in the main-sequence slope that would decrease the strength of debilitating spasms. Collectively, these data extend the knowledge of the pathophysiology of BEB and, perhaps more important, establish the role of blink system plasticity in eyelid movement disorders.
(+)-Pinoresinol/(+)-Lariciresinol Reductase from Forsythia intermedia

Lignans are a widely distributed class of natural products, whose functions and distribution suggest that they are one of the earliest forms of defense to have evolved in vascular plants; some, such as podophyllotoxin and enterodiol, have important roles in cancer chemotherapy and prevention, respectively. Entry into lignan enzymology has been gained by the ∼3000-fold purification of two isoforms of (+)-pinoresinol/(+)-lariciresinol reductase, a pivotal branchpoint enzyme in lignan biosynthesis. Both have comparable (∼34.9 kDa) molecular mass and kinetic (Vmax/Km) properties and catalyze sequential, NADPH-dependent, stereospecific, hydride transfers where the incoming hydride takes up the pro-R position. The gene encoding (+)-pinoresinol/(+)-lariciresinol reductase has been cloned and the recombinant protein heterologously expressed as a functional β-galactosidase fusion protein. Its amino acid sequence reveals a strong homology to isoflavone reductase, a key branchpoint enzyme in isoflavonoid metabolism and primarily found in the Fabaceae (angiosperms). This is of great evolutionary significance since both lignans and isoflavonoids have comparable plant defense properties, as well as similar roles as phytoestrogens. Given that lignans are widespread from primitive plants onwards, whereas the isoflavone reductase-derived isoflavonoids are mainly restricted to the Fabaceae, it is tempting to speculate that this branch of the isoflavonoid pathway arose via evolutionary divergence from that giving the lignans.
Lyapunov and converse Lyapunov theorems for semistability

This paper develops Lyapunov and converse Lyapunov theorems for semistable nonlinear dynamical systems. Semistability is the property whereby the solutions of a dynamical system converge to (not necessarily isolated) Lyapunov stable equilibrium points determined by the system initial conditions. Specifically, we provide necessary and sufficient conditions for semistability and show that semistability implies the existence of a smooth Lyapunov function that decreases along the dynamical system trajectories such that the Lyapunov function satisfies inequalities involving the distance to the set of equilibria.
Contractures in orthopaedic and neurological conditions: a review of causes and treatment

Purpose : To examine the techniques used for the treatment of contracture in the context of current scientific knowledge of muscle. Method : Synthesis of data available from MEDLINE, RECAL, EMBASE, the Cochrane Library and relevant texts. Results : The development of contractures through immobilisation, muscle weakness and spasticity is described. The effects of passive stretching, continuous passive movement, serial plastering, splinting, electrical stimulation, botulinum injections and surgical tenotomies in the treatment of contractures in persons with neurological and orthopaedic conditions are identified. The strengths and weaknesses of these modalities are discussed. Conclusion : Predisposing factors persist after treatment of contractures thus for treatment to be effective long-term management programmes need to be developed. New treatment techniques, used in series or combined, offer the prospect of improved management of contracture. Scientific and clinical research is needed to investigate the effect of contracture treatment.
Generalized connectivity of (n, k)-Star graphs

This paper considers Rh-connectivity of the (n, k)-star graph Sn,k, denoted by κh(Sn,k). In this note, We determine κh(Sn,k) = n+h(k−2)−1 for 2 ≤ k ≤ n−1 and 0 ≤ h ≤ n−k. The results generalize the main result in proved by W. H. Yang et al. [Information Processing Letters, 110(2010), 1007–1011] for the R1-connectivity (κ1(Sn,k)) and R2-connectivity (κ2(Sn,k)).
Compact model and projection of silicon nanowire tunneling transistors (NW-tFETs)

We present in this paper a basic compact model incorporating several key physical mechanisms in nanowire tunneling field-effect transistors (NW-tFETs), such as non-constant subthreshold swing (SS), definition of an on voltage, ballistic transport for carriers in the channel, and quantum capacitance limit (QCL). Using experimental data from [1], the validity of this model is verified. Further, to project the performance of ultra-scaled silicon NW-tFETs, we compare the state-of-the-art gate-all-around (GAA) NW MOSFETs [2] with modeling results for the same NW diameter and EOT (effective oxide thickness). It is concluded that ultra-scaled NW-tFETs can achieve high performance with low subthreshold swing (SS) and nearly the same on current as in MOSFETs.
A 0.8 V low-power CMOS PTAT voltage reference

The fundamental principles of the substrate bipolar transistor in CMOS technology and the bulk-driven MOSFET are discussed and analyzed. Based on the bulk-driven PMOSFET, substrate PNP transistor and current feedback technique an 0.8 V low power PTAT voltage reference is proposed for the temperature sensors applications. At a 0.8 V power supply with -25/spl sim/130 /spl deg/C temperature range, the temperature coefficient of voltage reference is 0.926 mV/K, and the supply current is about 4.5 /spl mu/V. When the power supply ranged 0.7 V/spl sim/1.0 V, the voltage reference is about 302 mV in the room temperature. The active area of reference is about 0.01 mm/sup 2/.
Meta-Analysis of fMRI Studies of Disruptive Behavior Disorders.

OBJECTIVE Functional magnetic resonance imaging (fMRI) studies in conduct disorder and in oppositional defiant disorder have shown inconsistencies. The aim of this meta-analysis of fMRI studies in disruptive behavior disorders was to establish the most consistent brain dysfunctions and to address task- and subtype-related heterogeneity. METHOD Web-based publication databases were searched to conduct a meta-analysis of all whole-brain fMRI studies of youths with disruptive behavior disorder or conduct problems up to August 2015. Sub-meta-analyses were conducted in functional subdomains of emotion processing; in cool and hot executive functions, which refer to goal-directed higher cognitive functions with and without motivational and affective significance; and in a subgroup of youths with additional psychopathic traits. The authors performed a meta-analysis of voxel-based group differences in functional activation using the anisotropic effect-size version of seed-based d mapping. RESULTS Across 24 studies, 338 youths with disruptive behavior disorder or conduct problems relative to 298 typically developing youths had consistent underactivation in the rostral and dorsal anterior cingulate and in the medial prefrontal cortex and ventral caudate. Sub-meta-analyses of fMRI studies showed that medial fronto-cingulate dysfunction was driven by hot executive function. The sub-meta-analysis of emotion processing fMRI studies showed the most consistent underactivation in the dorsolateral prefrontal cortex and temporal pole, while cool executive functions were associated with temporal abnormalities. Youths with disruptive behavior disorder with psychopathic traits showed reduced ventromedial prefrontal-hypothalamic-limbic activation, but they also showed hyperactivation in cognitive control mediating dorsolateral prefrontal-dorsal and striatal regions. CONCLUSIONS The findings show that the most consistent dysfunction in youths with disruptive behavior disorder is in the rostro-dorsomedial, fronto-cingulate, and ventral-striatal regions that mediate reward-based decision making, which is typically compromised in the disorder. Youths with psychopathic traits, on the other hand, have dysfunctions associated with the ventromedial prefrontal cortex and limbic system, together with dorsal and fronto-striatal hyperfunctioning, which may reflect poor affect reactivity and empathy in the presence of hyperactive executive control. These findings provide potential targets for neurotherapeutic and pharmacological interventions.
Recursive algorithms for the matrix Padé problem

Abstract. A matrix triangularization interpretation is given for the recursive algorithms computing the Padd approximants along a certain path in the Padd table, which makes it possible to unify all known algorithms in this field [51, [61. For the normal Padd table, all these results carry over to the matrix Padd problem in a straightforward way. Additional features, resulting from the noncommutativity are investigated. A generalization of the Trench-Zohar algorithm and related recursions are studied in greater detail.
Nanoscale laminin coating modulates cortical scarring response around implanted silicon microelectrode arrays

Neural electrodes could significantly enhance the quality of life for patients with sensory and/or motor deficits as well as improve our understanding of brain functions. However, long-term electrical connectivity between neural tissue and recording sites is compromised by the development of astroglial scar around the recording probes. In this study we investigate the effect of a nanoscale laminin (LN) coating on Si-based neural probes on chronic cortical tissue reaction in a rat model. Tissue reaction was evaluated after 1 day, 1 week, and 4 weeks post-implant for coated and uncoated probes using immunohistochemical techniques to evaluate activated microglia/macrophages (ED-1), astrocytes (GFAP) and neurons (NeuN). The coating did not have an observable effect on neuronal density or proximity to the electrode surface. However, the response of microglia/macrophages and astrocytes was altered by the coating. One day post-implant, we observed an ∼60% increase in ED-1 expression near LN-coated probe sites compared with control uncoated probe sites. Four weeks post-implant, we observed an ∼20% reduction in ED-1 expression along with an ∼50% reduction in GFAP expression at coated relative to uncoated probe sites. These results suggest that LN has a stimulatory effect on early microglia activation, accelerating the phagocytic function of these cells. This hypothesis is further supported by the increased mRNA expression of several pro-inflammatory cytokines (TNF-α, IL-1 and IL-6) in cultured microglia on LN-bound Si substrates. LN immunostaining of coated probes immediately after insertion and retrieval demonstrates that the coating integrity is not compromised by the shear force during insertion. We speculate, based on these encouraging results, that LN coating of Si neural probes could potentially improve chronic neural recordings through dispersion of the astroglial scar.
Image Denoising Based on Support Vector Machine

Image in the collection, transmission and other processes, often affected to some extent, resulting in noise. The purpose of image denoising is obtained from the degraded image noise removal, restore the original image. Traditional denoising methods can filter noise, but at the same time they make the image details fuzzy. The support vector machine based method for image denoising is a good method, thus it can not only wipe of noise, but also retain the image detail. Support vector machine is a machine learning, which based on statistical learning theory, and this method is widely applied to solve classification problems. This paper proposes an image denoising method based on support vector regression; also this paper describes several other methods of image denoising. Simulation results show that the method can save the image detail better, restore the original image and remove noise.
Gastric hyperplasia in mice with targeted disruption of the carbonic anhydrase gene Car9.

BACKGROUND & AIMS Carbonic anhydrase (CA) IX is a highly active enzyme with adhesion capacity that is functionally implicated in acid-base balance and intercellular communication. It is normally present in basolateral membranes of gastrointestinal epithelial cells and ectopically expressed in various carcinomas. To show its physiologic relevance, we have cloned the Car9 gene and generated CA IX-deficient mice. METHODS The mice with null mutation of the Car9 gene were obtained by targeted gene disruption. Tissue architecture and expression of markers were determined by histochemical and immunohistochemical techniques. RESULTS Mice homozygous for the mutation developed gastric hyperplasia of the glandular epithelium with numerous cysts. The first changes were observed in the newborn animals, and the hyperplasia became prominent at the end of gastric morphogenesis in 4-week-old mice. Loss of CA IX led to overproduction of mucus-secreting pit cells and depletion of pepsinogen-positive chief cells. The proportion of H(+)/K(+)-adenosine triphosphatase-positive parietal cells significantly decreased, but their absolute number was not reduced. Correspondingly, CA IX-deficient mice had normal gastric pH, acid secretion, and serum gastrin levels. CONCLUSIONS Phenotypic consequences of the Car9 null mutation show the important role of CA IX in morphogenesis and homeostasis of the glandular gastric epithelium via the control of cell proliferation and differentiation.
11β-hydroxysteroid dehydrogenase types 1 and 2 activity in subcutaneous adipose tissue in humans: implications in obesity and diabetes.

CONTEXT The role of 11β-hydroxysteroid dehydrogenase types 1 (11β-HSD-1) and 2 (11β-HSD-2) enzymes in sc adipose tissue is controversial. OBJECTIVE The objective of the study was to determine the activity of 11β-HSD-1 and -2 enzymes in the abdominal and leg sc adipose tissue in obesity and diabetes. DESIGN 11β-HSD-1 and -2 enzyme activities in abdominal and leg sc adipose tissue were measured by infusing [2,2,4,6,6,12,12-(2)H7] cortisone (D7 cortisone) and [9,12,12-(2)H3] cortisol (D3 cortisol) via microdialysis catheters placed in sc fat depots. SETTING The study was conducted at the Mayo Clinic Clinical Research Unit. PARTICIPANTS Lean nondiabetic (n = 13), overweight/obese nondiabetic (n = 15), and overweight/obese participants with type 2 diabetes mellitus (n = 15) participated in the study. MAIN OUTCOME MEASURES The conversion of infused D7 cortisone to D7 cortisol (via 11β-HSD reductase activity) and D3 cortisol to D3 cortisone (via 11β-HSD dehydrogenase activity) in sc adipose tissue. RESULTS Enrichment of D7 cortisone and D3 cortisol were similar in the effluents from both sites in all groups. D3 cortisone enrichment did not differ in the three cohorts, indicating that 11β-HSD-2 enzyme activity (conversion of cortisol to cortisone) occurs equally in all groups. However, D7 cortisol enrichment was detectable in abdominal sc fat of overweight/obese participants with type 2 diabetes mellitus only, implying 11β-HSD-1 reductase activity (conversion of cortisone to cortisol) occurs in obese subjects with type 2 diabetes. CONCLUSIONS There is conversion of cortisone to cortisol via the 11β-HSD-1 enzyme pathway in abdominal sc fat depots in overweight/obese participants with type 2 diabetes mellitus. This observation has significant implications for developing tissue-specific 11β-HSD-1 inhibitors in type 2 diabetes mellitus.
Mixed viewpoints in factual and fictive discourse in Catalan Sign Language narratives

This chapter is based on in-depth qualitative analysis of original elicited and naturalistic narratives from 20 native signers of Catalan Sign Language. Signed languages are especially interesting for the study of mixed viewpoints, since their grammar is characterized by viewpoint shift (Herrmann and Steinback 2012). They also lend themselves particularly well for the study of conversational constructions, such as direct discourse, as they are typically used in situated intersubjective interaction. We focus on the use of role shift to set up non-genuine quotes in Catalan Sign Language narratives. In particular, we examine multifunctional or polysemic direct discourse, which is characterized by (mixed) viewpoints. In signed languages direct discourse may serve to represent a referent’s utterances, actions, thoughts, emotions, attitudes and source of information. We show that despite its complexity, constructed action, which involves multiple perspectives, is a central component of Catalan Sign Language narratives. In fact, although alternative descriptive constructions do exist, native signers consider constructed action as the most unmarked (cf. Quinto-Pozos 2007). We further propose that the structure of mixed viewpoints in narratives – and in grammar – mimics the mode in which language is mostly used, namely intersubjective conversation, characterized by constant perspective shifting.