Miracle-dz/UniFAR-FTUs huggingface dataset:
Genetic diversity of the endangered argan tree ( Argania spinosa L . ) ( sapotaceae ) revealed by ISSR analysis

Genetic variation in 150 trees of A. spinosa was estimated using inter-simple sequence repeat (ISSR). The plant material used in this study were originated from five provenances belonging to the principal provinces of argan ecosystem in southwest of Morocco. Based on the nine ISSR primers, 86 loci were scored. At the population level, percentage of polymorphic bands (PPB) was ranged from 75.58 to 82.56 %, Nei’s genetic diversity index (H) ranged from 0.30 to 0.34, Shannon’s information index (I) ranged from 0.44 to 0.49. Analyses of spatial genetic structure using UPGMA, the principal coordinate analysis and Bayesian-based approach from Structure program, showed that the entire provenances were successfully assigned to three groups. There was no significant correlation between genetic distance and geographic distance by Mantel test (r = 0.026, P = 0.942). The genetic differentiation coefficient (Gst = 0.22) was high, it was similar to the result of the analysis of molecular variance (28 % of the total variation among provenances). According to the genetic diversity results, the conservation and improvement strategies should be taking in consideration the provenance factor. So this study should be made appropriately the large sampling for the better representing of all diversity existing on the scale of the natural distribution of the argan.
Socialização materna e comprometimento dos filhos com os direitos humanos

Este artigo tem como objetivo geral apresentar a relacao entre o uso pelas maes de uma tecnica indutiva de socializacao – dialogo, conversacao das maes com seus filhos – e o grau de comprometimento dos filhos com os Direitos Humanos - DH. Participaram da presente pesquisa 100 diades (mae – filho), totalizando 200 participantes (100 maes e 100 filhos). Os filhos frequentavam escola privada e tinham entre 12 e 17 anos de idade e as maes possuiam idade media de 46 anos. Para os filhos foram aplicadas a Escala de Percepcao Materna de Direitos Humanos (EPMDH) e Escala de Comprometimento com os Direitos Humanos (ECDH), para as maes, a Escala de Verbalizacao Materna sobre os Direitos Humanos (EVMDH). Os dados foram analisados no programa SPSS que permitiu caracterizar a amostra e comparar os diferentes escores das escalas, bem como, verificar se havia correlacoes entre as variaveis. Os resultados indicaram que ha correlacao significativa e positiva entre o que as maes dizem verbalizar acerca dos Direitos Humanos com seus filhos, o que eles percebem que elas verbalizam e o comprometimento deles com a luta em defesa dos DH no futuro.
A Jigsaw query processing technique for Web GIS

As computing environments for the Internet have been expanding, research on Internet GIS has developed. The omnipresence and easiness of the Web focuses the research on Web GIS. Web GIS is classified into a server-side Web GIS and client-side Web GIS. The former can easily be implemented but raises the overload of the server, the latter lessens the overload of the server, but raises some problems. To solve these problems, this paper proposes a Jigsaw query processing technique that processes user queries dynamically. For an evaluation, the detailed experiments such as map browsing, layer control, point query and region query are conducted comparing the proposed technique with the two other methods. Based on the results of experiments, the proposed technique can give the user a fast response and increase system performance.
Inter-controller traffic in ONOS clusters for SDN networks

In distributed SDN architectures, the network is controlled by a cluster of multiple controllers. This distributed approach permits to meet the scalability and reliability requirements of large operational networks. Despite that, a logical centralized view of the network state should be guaranteed, enabling the simple development of network applications. Achieving a consistent network state requires a consensus protocol, which generates control traffic among the controllers whose timely delivery is crucial for network performance. We focus on the state-of-art ONOS controller, designed to scale to large networks, based on a cluster of self-coordinating controllers, and concentrate on the inter-controller control traffic. Based on real traffic measurements, we develop a model to quantify the traffic exchanged among the controllers, which depends on the topology of the controlled network. This model is useful to design and dimension the control network interconnecting the controllers.
Conceptual Graphs as Framework for Summarizing Short Texts

In this paper, a conceptual graph-based framework for summarizing short texts is proposed. A semantic representation is implemented through conceptual graph structures that consist of concepts and conceptual relations that stand for texts. To summarize conceptual graphs, the most important nodes are selected using a set of operations: generalization, association, ranking, and pruning, which are described. The importance of nodes on weighted conceptual graphs is measured using a modified version of HITS algorithm. In addition, some heuristic rules are used to keep coherent structures based on information from WordNet hierarchy of concepts and VerbNet semantic patterns of verbs. The experimental results show that this approach is effective in summarizing short texts.
Faithful Effective-One-Body waveforms of equal-mass coalescing black-hole binaries

We compare a recently derived, resummed high post-Newtonian accuracy effective-one-body (EOB) quadrupolar waveform to the results of a numerical simulation of the inspiral and merger of an equal-mass black-hole binary. We find a remarkable agreement, both in phase and in amplitude, with a maximal dephasing which can be reduced below {+-}0.005 gravitational-wave cycles over 12 gravitational-wave cycles corresponding to the end of the inspiral, the plunge, the merger, and the beginning of the ring-down. This level of agreement is shown for two different values of the effective fourth post-Newtonian parameter a{sub 5}, and for corresponding, appropriately flexed values of the radiation-reaction resummation parameter v{sub pole}. In addition, our resummed-EOB amplitude agrees to better than the 1% level with the numerical-relativity one up to the late inspiral. These results, together with other recent work on the EOB-numerical-relativity comparison, confirm the ability of the EOB formalism to accurately capture the general-relativistic waveforms.
8‐Year‐Old Boy with Progressive Headache

An 8-year-old boy with no significant past medical history presented to the emergency department following 2 weeks of progressive headaches, fatigue, and vomiting. On physical examination, the patient had no fever, or focal motor or sensory neurological deficits. Initially diagnosed with an H1N1 viral upper respiratory and gastrointestinal infection, he was discharged home with conservative management. After failure to improve over the next several days, a superimposed bacterial infection was suspected. He was given a course of oral antibiotics, which failed to improve his symptoms. Imaging revealed a large, heterogenously enhancing mass measuring 5.6 × 4.7 × 5.2 cm, which contained partially hemorrhagic material centered within the left thalamus extending into the body of the lateral ventricle (Figures 1a). Gross total resection of the tumor was confirmed by postoperative imaging. Staging revealed no metastases. The patient was discharged home 1 week later. NEUROPATHOLOGICAL FINDINGS
Non-participation in EIRA: a population-based case–control study of rheumatoid arthritis

In epidemiological studies, non-participation may result in selection bias (1) and information on who is likely to participate is therefore essential for interpretation. It has been observed that non-participants are more likely to be men (2–5), young or old (2–6), unmarried (2, 4, 5), urban residents (3), of low socioeconomic status (2–5), and to have increased mortality (2, 6). Sociodemographic characteristics of non-participants have been described in studies of different diseases but not so far in studies of incident rheumatoid arthritis (RA). A population-based case–control study on incident cases of RA, called EIRA (Epidemiological Investigation of Rheumatoid Arthritis), has been in progress in Sweden since 1996 (7, 8). In the current report we investigated potential sociodemographic differences of study participants and non-participants and whether these differences might have introduced selection bias. The study base comprised the population, aged 18– 70 years, living in parts of Sweden during May 1996– December 2005. Incident cases of RA, according to the American College of Rheumatology (ACR) criteria of 1987 (9), were continuously reported to EIRA. Controls were randomly selected from the study base and matched to the cases according to sex, age, and residential area. Both cases and controls answered a questionnaire covering a wide spectrum of issues, including lifestyle and occupational exposures. Of 2010 reported cases and 2715 selected controls, 1931 cases (96%) and 2214 controls (82%) responded to the questionnaire. To determine whether all RA cases that occurred in the study base were reported to EIRA, we linked EIRA data with data from the national Swedish RA register. In total, 359 incident RA cases were included in the RA register but were not reported to EIRA (Figure 1). Thus, a total of 2369 cases were identified in the study base, giving a participation proportion of 82% among all cases. For all study subjects (all selected controls and identified cases), we collected sociodemographic information, stemming from 2001, from registers at Statistics Sweden. The demographic variables included sex, age, marital status, and inhabitants in residential area, and the socioeconomic variables included individual income, birth country, and educational level. We analysed the distribution of each variable among participants and
Optimized receiver design for decode-and-forward relays using hierarchical modulation

We consider a wireless relay network with a single source, a single destination, and multiple relays. The relays are half-duplex and use the decode-and-forward protocol. The transmit source is a layered bitstream, which can be partitioned into two layers. The source broadcasts both layers to all the relays and the destination using hierarchical 16-QAM. Each relay detects and transmits successfully decoded layers to the destination using either hierarchical 16-QAM or QPSK using orthogonal channels. We derive the optimal linear-combining receiver at the destination, where the uncoded bit error rate is minimized. We also present a suboptimal combining method with a closed-form solution, which performs very close to the optimal. Numerical results show that the two-layer scheme outperforms the classical one-layer scheme using conventional modulation.
Recent developments in the understanding and management of paroxysmal nocturnal haemoglobinuria

Paroxysmal nocturnal haemoglobinuria (PNH) has been recognised as a discrete disease entity since 1882. Approximately a half of patients will eventually die as a result of having PNH. Many of the symptoms of PNH, including recurrent abdominal pain, dysphagia, severe lethargy and erectile dysfunction, result from intravascular haemolysis with absorption of nitric oxide by free haemoglobin from the plasma. These symptoms, as well as the occurrence of thrombosis and aplasia, significantly affect patients’ quality of life; thrombosis is the leading cause of premature mortality. The syndrome of haemolytic‐anaemia‐associated pulmonary hypertension has been further identified in PNH patients. There is currently an air of excitement surrounding therapies for PNH as recent therapeutic developments, particularly the use of the complement inhibitor eculizumab, promise to radically alter the symptomatology and natural history of haemolytic PNH.
Genotype and clinical care correlations in craniosynostosis: Findings from a cohort of 630 Australian and New Zealand patients

Craniosynostosis is one of the most common craniofacial disorders encountered in clinical genetics practice, with an overall incidence of 1 in 2,500. Between 30% and 70% of syndromic craniosynostoses are caused by mutations in hotspots in the fibroblast growth factor receptor (FGFR) genes or in the TWIST1 gene with the difference in detection rates likely to be related to different study populations within craniofacial centers. Here we present results from molecular testing of an Australia and New Zealand cohort of 630 individuals with a diagnosis of craniosynostosis. Data were obtained by Sanger sequencing of FGFR1, FGFR2, and FGFR3 hotspot exons and the TWIST1 gene, as well as copy number detection of TWIST1. Of the 630 probands, there were 231 who had one of 80 distinct mutations (36%). Among the 80 mutations, 17 novel sequence variants were detected in three of the four genes screened. In addition to the proband cohort there were 96 individuals who underwent predictive or prenatal testing as part of family studies. Dysmorphic features consistent with the known FGFR1‐3/TWIST1‐associated syndromes were predictive for mutation detection. We also show a statistically significant association between splice site mutations in FGFR2 and a clinical diagnosis of Pfeiffer syndrome, more severe clinical phenotypes associated with FGFR2 exon 10 versus exon 8 mutations, and more frequent surgical procedures in the presence of a pathogenic mutation. Targeting gene hot spot areas for mutation analysis is a useful strategy to maximize the success of molecular diagnosis for individuals with craniosynostosis. © 2013 Wiley Periodicals, Inc.
Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.

Importin-alpha is the nuclear import receptor that recognizes cargo proteins which contain classical monopartite and bipartite nuclear localization sequences (NLSs), and facilitates their transport into the nucleus. To determine the structural basis of the recognition of the two classes of NLSs by mammalian importin-alpha, we co-crystallized an N-terminally truncated mouse receptor protein with peptides corresponding to the monopartite NLS from the simian virus 40 (SV40) large T-antigen, and the bipartite NLS from nucleoplasmin. We show that the monopartite SV40 large T-antigen NLS binds to two binding sites on the receptor, similar to what was observed in yeast importin-alpha. The nucleoplasmin NLS-importin-alpha complex shows, for the first time, the mode of binding of bipartite NLSs to the receptor. The two basic clusters in the NLS occupy the two binding sites used by the monopartite NLS, while the sequence linking the two basic clusters is poorly ordered, consistent with its tolerance to mutations. The structures explain the structural basis for binding of diverse NLSs to the sole receptor protein.
Adjuvant Intra-arterial Iodine-131-labeled Lipiodol for Resectable Hepatocellular Carcinoma: A Prospective Randomized Trial—Update on 5-Year and 10-Year Survival

Objective:In this prospective randomized trial, we attempted to find out if 1 dose of postoperative adjuvant intra-arterial iodine-131-labeled lipiodol could reduce the rate of local recurrence, and increase disease-free and overall survival for patients with hepatocellular carcinoma (HCC). This study evaluated the long-term outcome. Background:Resection of HCC is potentially curative, but local recurrence is common. However, there is currently no effective adjuvant therapy. Early results after closing the trial (Lau et al. Lancet 1999;353:797–801) showed that 1 dose of intra-arterial 131I-lipiodol given after curative resection significantly decreased the rate of recurrence, and increased disease-free and overall survival. Methods:Patients who underwent curative resection for HCC and recovered within 6 weeks were randomly assigned one 1850 MBq dose of 131I-lipiodol or no further treatment (controls). We compared rates of recurrence, and long-term disease-free and overall survival (the primary endpoints) between the 2 groups by intention-to-treat. Results:Between April 1992 and August 1997, we recruited 43 patients: 21 were randomized to receive intra-arterial 131I-lipiodol and 22 to receive no adjuvant treatment. 131I-lipiodol had no significant toxic effects. During a median follow-up of 66 (range, 3–198) months, there were 10 (47.6%) recurrences among the 21 patients in the adjuvant treatment group, compared with 14 (63.6%) in the control group (P = 0.29). The actuarial 5-year disease-free survival in the treatment and control groups was 61.9% and 31.8%, respectively (P = 0.0397). The actuarial 5-year overall survival in the treatment and control groups was 66.7% and 36.4%, respectively (P = 0.0433). The actuarial 7-year disease-free survival in the treatment and control groups was 52.4% and 31.8%, respectively (P = 0.0224). The actuarial 7-year overall survival in the treatment and control groups was 66.7% and 31.8%, respectively (P = 0.0243). The actuarial 10-year disease-free survival in the treatment and control groups was 47.6% and 27.3%, respectively (P = 0.0892). The actuarial 10-year overall survival in the treatment and control groups was 52.4% and 27.3%, respectively (P = 0.0905). Conclusions:In patients with HCC, adjuvant intra-arterial 131I-lipiodol after curative liver resection provided survival benefit on the disease-free survival and overall survival, although the difference became statistically insignificant at 8 years after randomization.
A study of acoustic features for depression detection

Clinical depression can be considered as a soft biometric trait that can help to characterize an individual. This mood disorder can be involved in forensic psychological assessment, due to its relevance in different legal issues. The automatic detection of depressed speech has been object of research in the last years, resulting in different algorithmic approaches and acoustic features. Due to the use of different algorithms, databases and performance measures, deciding which ones are more suitable for this task is difficult. In this work, the performance of different acoustic features for depression detection was explored in a common framework. To do so, a depression estimation approach in which the audio data is segmented and projected into a total variability subspace was used, and these projected data was used to estimate the depression level by performing support vector regression. The data and evaluation metrics were the ones used in the audiovisual emotion challenge (AVEC 2013).
Phoneme recognition with a time-delay neural network

A time-delay neural network architecture is used for speaker-dependent recognition of the long vowel sounds a, e, and i. The following areas are investigated: increasing the amount of data supplied to the network, allowing longer and variable-length utterances, and using English rather than Japanese speech. With this architecture, 100% recognition has been obtained for a population of six speakers
PSO-based time-domain antenna synthesis for enhanced UWB communication systems

In this paper, an approach for the synthesis of antenna systems suitable for UWB communication applications has been presented. The final antenna geometry is obtained by means of a PSO aimed at fitting a set of time domain requirements. Such requirements allow the radiating system to have an high efficiency, distortionless properties, and omnidirectional radiation patterns over the whole frequency range. An example of synthesized antenna has been shown as a preliminary assessment of the proposed approach.
Impact of isoniazid preventive therapy on mortality among children less than 5 years old following exposure to tuberculosis at home in Guinea-Bissau: a prospective cohort study

Objective In a cohort of children less than 5 years old exposed to adult intrathoracic tuberculosis (TB) in 1996–1998, we found 66% increased mortality compared with community controls. In 2005, we implemented isoniazid preventive therapy (IPT) for children exposed to TB at home, and the present study evaluates the effect of this intervention on mortality. Setting This prospective cohort study was conducted in six suburban areas included in the demographic surveillance system of the Bandim Health Project in Bissau, the capital city of Guinea-Bissau. Participants All children less than 5 years of age and living in the same house as an adult with intrathoracic TB registered for treatment in the study area between 2005 and 2007 were evaluated for inclusion in the IPT programme. Main outcome measures (end points) The all-cause mortality rate ratio (MRR) between exposed children on IPT, exposed without IPT and unexposed community control children. Results A total of 1396 children were identified as living in the same houses as 416 adult TB cases; of those, 691 were enrolled in the IPT programme. Compared with community controls, the IPT children had an MRR of 0.30 (95%CI 0.1 to 1.2). The MRR comparing exposed children with and without IPT was 0.21 (0.0 to 1.1). The relative mortality in IPT children compared with community controls in 2005–2008 differed significantly from the relative mortality of exposed untreated children compared with the community controls in 1996–1998 (test of interaction, p=0.01). Conclusions In 2005–2008, exposed children on IPT had 70% lower mortality than the community control children, though not significantly. Relative to the community control children, the mortality among TB-exposed children on IPT in 2005–2008 was significantly lower than the mortality among TB-exposed children not on IPT in 1996–1998.
RF system requirement analysis and simulation methods towards 5G radios using massive MIMO

Methods of performing RF system requirement analysis towards 5th generation massive multiple-input multiple-output system are described. For the system analysis, digital signal processing is abstracted to minimum SNR requirement definitions and RF system SNR is described based on realistic but highly simplified transmitter and receiver performance related to output and input power levels, respectively. In addition, a simple link adaptation model is created for dynamic simulation tasks. As the contribution of antenna array is seen to become necessity in cm- and mm-wave bands for 5G systems, we show ways to include antenna modelling in system analysis. By using these analysis methods, we have generated a link level simulator that can be used for system analysis using different abstractions of antennas. Finally, it is shown that even simple RF models need to have certain implementation related details in order to provide good accuracy in link budget and operation range analysis.
Análisis de la flota sardinera - anchovetera del noroeste de México

Se hace un analisis de la flota sardinera-anchovetera del Noroeste de Mexico, con especial enfasis en su eficiencia operativa de pesca. Dicho analisis comprende aspectos relacionados con las caracteristicas de las embarcaciones; asi mismo, se determina la eficiencia operativa de la flota por dos vias; una estimando los poderes relativos de pesca con ayuda del la CPUE y por el otro lado se evalua la capacidad de bodega utilizada por los barcos en terminos de porcentaje. Se hace tambien una proyeccion del potencial de pesca por parte de la flota y se relaciona la movilidad de dicha flota con su eficiencia. El estudio concluye que la dimension de la flota actual no debe incrementarse, que barcos "chicos" y "grandes" operan diferencialmente de acuerdo al recurso sobre el cual esten actuando (sardina o anchoveta), que la categoria de barcos mas eficientes operativamente hablando son los de 101 - 150 toneladas de capacidad de bodega y que es necesario un adecuado manejo de la flota en su conjunto (movilidad de la flota) para incrementar los volumenes de captura sin necesidad de que la flota sufra un incremento en su numero, procurando con ello evitar sobre capitalizacion en la fase extractiva en particular y de la pesqueria en lo general.