Miracle-dz/UniFAR-FTUs huggingface dataset:
Detection of Anaplasma marginale rickettsemia prior to onset of clinical signs by using an antigen capture enzyme-linked immunosorbent assay

An antigen capture enzyme-linked immunosorbent assay was developed by using monoclonal antibodies to conserved epitopes on the Anaplasma marginale MSP1a surface protein. The assay sensitivity was 1.1 (+/- 0.5)% parasitized erythrocytes, and all infected cattle were detected prior to development of 2.0%-parasitized erythrocytes. Positive tests preceded the onset of anemia by a mean of 2 days. The assay was specific for anaplasmosis, as demonstrated by nonreactivity with another common hemoparasitic pathogens.
Toward individualized SAR models and in vivo validation

The specific absorption rate (SAR) is a limiting constraint in sequence design for high‐field MRI. SAR estimation is typically performed by numerical simulations using generic human body models. This entails an intrinsic uncertainty in present SAR prediction. This study first investigates the required detail of human body models in terms of spatial resolution and the number of soft tissue classes required, based on finite‐differences time‐domain simulations of a 3 T body coil. The numerical results indicate that a resolution of 5 mm is sufficient for local SAR estimation. Moreover, a differentiation between fatty tissues, water‐rich tissues, and the lungs was found to be essential to represent eddy current paths inside the human body. This study then proposes a novel approach for generating individualized body models from whole‐body water‐fat‐separated MR data and applies it to volunteers. The SAR hotspots consistently occurred in the arms due to proximity to the body coil as well as in narrow regions of the muscles. An initial in vivo validation of the simulated fields in comparison with measured B1‐field maps showed good qualitative and quantitative agreement. Magn Reson Med, 2011. © 2011 Wiley Periodicals, Inc.
Kyphoscoliosis and easy fatigability in a 14‐year‐old boy

Thepatientwasa14-year-oldThaiboywhopresentedatanorthopedic clinic with kyphoscoliosis ﬁrst detected 1 yearprior to medical attention. He was the ﬁrst child of non-consanguineous parents; the pregnancy and delivery wereuneventful.He had normal developmental milestones.Thepatient noticed easy fatigability after exercise which wors-ened during the past year. His younger brother was 10years old and healthy. There was no history ofneuromuscular disease in his family. His father passedaway due to an unrelated incident. General examinationrevealed a body weight of 30 kg and a height of 149 cm,bilateral ptosis, high-arched palate, kyphoscoliosis, andasymmetrical chest wall. Proximal muscle weakness ofgrade 4 by Medical Research Council Scale in all extrem-itiesandareﬂexiawerenoted. Themuscletonewasnormal.SerumCKwas49 IU/L.Echocardiogramshowedmildpul-monary and tricuspid regurgitation. Pulmonary functiontestsshowedrestrictivelungdisease;theforcedvitalcapac-ity was 1.56 L (51% of predicted). Sleep study revealedapnea-hypopnea index 13.6 per hour associated withsevere oxygen desaturation (minimum SpO
Selective degeneration of CA1 pyramidal cells by chronic application of bismuth

The heavy metal bismuth induces a new type of selective neuronal degeneration that shares some common aspects with that seen following hypoxia and ischemia. Continuous application of 3 μm bismuth to organotypic cultures of rat hippocampus resulted after 2–3 weeks in selective degeneration of CA1 pyramidal cells, while CA3 pyramidal cells, dentate granule cells, and subicular neurons were resistant. With 10 μm MK‐801, a noncompetitive NMDA‐antagonist, during the entire culturing period failed to prevent neuronal degeneration induced by 3 μm bismuth. GABA‐immunoreactive interneurons were also affected by bismuth, but were generally less sensitive than CA1 pyramidal cells. Acute application of up to 100 μm bismuth did not change the electrophysiological properties of CA1 pyramidal cells. © 1994 Wiley‐Liss, Inc.
Multiple Noncontiguous Spine Fractures

The data from a prospective study of 508 spine injuries were reviewed to determine the incidence of multiple noncontiguous spine fractures. All patients were examined at admission and at 1 and 2 years postinjury. This series identified 77 (155%) multilevel fractures. Motor vehicle accidents were the primary cause of these fractures. The incidence of neurologte injury was not signifl-carrth/different between multiple noncontiguous and single fractures. Failure to use seat belts and ejection from the vehicle were the main factors associated with multiple noncontiguous spine injuries. Seven major fracture patterns were Identified, which accounted for 60% of these injuries. The prognosis for multilevel spine fractures was not significantly worse than that for single-level injuries.
Molecular dynamics investigation on temperature-dependent thermal expansion and elastic properties of gallium nitride nanorods

The coefficients of thermal expansion (CTE) properties of gallium nitride nanorod with various temperatures were studied by using molecular dynamics methods. The influence of the mechanical pressure loading on the axial CTE was also extensively explored. The results indicate that the axial coefficients of thermal expansion increases with increasing temperatures, and decreases with increasing mechanical pressure loading. Besides, the axial CTE varies nonlinearly with the temperature. The curve becomes gradual as the temperature increases, indicating that the nanorod expands more slowly at higher temperature. Our theoretical results demonstrate that, the external mechanical loading decreases the thermal performance of gallium nitride nanorod.
Dental Cements: Reactor Response

This paper is in response to Dr. Dennis Smith's paper, which dealt with the current status of dental cements and recommendations with respect to future research needs. Interest in cements and research in this area have mushroomed with the development of polycarboxylate and glass-ionomer cements. Despite this increased research, there still exist significant voids, which can only be elucidated by further concerted research efforts, both laboratory and clinical. With newer systems-e.g., the polycarboxylate and glass-ionomer cements—properties such as modulus of elasticity, which were of little concern with the phosphate cements, have now assumed clinical relevance. Also, the need persists to develop an in vitro test that reflects the relative resistance of cements to disintegration in the oral cavity. Finally, greater efforts should be expended by the research community to disseminate new findings to the dental practitioner in order that the patient population may benefit from the latest advances in materials.
Improving the Robustness of TCP to Non-Congestion Events

This document specifies Non-Congestion Robustness (NCR) for TCP. In the absence of explicit congestion notification from the network, TCP uses loss as an indication of congestion. One of the ways TCP detects loss is using the arrival of three duplicate acknowledgments. However, this heuristic is not always correct, notably in the case when network paths reorder segments (for whatever reason), resulting in degraded performance. TCP-NCR is designed to mitigate this degraded performance by increasing the number of duplicate acknowledgments required to trigger loss recovery, based on the current state of the connection, in an effort to better disambiguate true segment loss from segment reordering. This document specifies the changes to TCP, as well as the costs and benefits of these modifications. This memo defines an Experimental Protocol for the Internet community.
[Experience with high-dose immunosuppressive therapy followed by transplantation of autologous stem hematopoietic cells in patients with multiple sclerosis].

AIM To assess efficiency of immunosuppressive therapy and subsequent autologous transplantation of stem blood cells (SBC) in patients with multiple sclerosis. MATERIAL AND METHODS The trial enrolled 23 patients (4 men and 19 women) with multiple sclerosis (MS) lasting for 3 to 12 years. The age of the patients ranged from 18 to 44 years. The index of the progression was above 1 in all the patients. A remitting, primary-progredient, secondary-progredient course was diagnosed in 3, 3 and 17 patients, respectively. Posttransplantation follow-up was 1 to 1.5 years. The degree of the neurological deficiency (0-6 scores) was estimated by the scale of functional systems damage. Lymphocyte subpopulations were evaluated by enzyme immunoassay according to expression of membrane antigens CD3, CD4, CD8, CD16, CD20, CD25, CD56, CD95 using monoclonal antibodies ICO (Biomedspectr), humoral immunity--by serum levels of IgA, IgM and IgG. SBC mobilization was conducted for 5 days by subcutaneous introduction of neipogen (Roche) in a dose 8.7-10 mcg/kg. Preparation of SBC was made on Haemonetics blood separator on mobilization day 4-5. Cryopreservation was carried out in programmed freezer (Cryomed) with 7% dimethylsulphoxide as a cryoprotector. Pretransplantation conditioning was conducted according to the schemes BEAM + antilymphocytic globulin (protocol N 1) and fludar + melfalan + ALG (protocol N 2). RESULTS In posttransplantation period most of the patients achieved a fall in intensity of motor and coordination disorders. No recovery of cranial nerve function was observed. The protocols of pretransplantation preparation were compared by efficiency and organic toxicity. CONCLUSION Indications to immunosuppressive therapy in MS patients were defined, pathogenetic validation of the immunosuppressive therapy was attempted.
An adaptive-learning approach to affect regulation: Strategic influences on evaluative priming

An adaptive cognition approach to evaluative priming is not compatible with the view that the entire process is automatically determined by prime stimulus valence alone. In addition to the evaluative congruity of individual prime–target pairs, an adaptive regulation function should be sensitive to the base rates of positive and negative stimuli as well as to the perceived contingency between prime and target valence. The present study was particularly concerned with pseudocontingent inferences that offer a proxy for the assessment of contingencies from degraded or incomplete stimulus input. As expected, response latencies were shorter for the more prevalent target valence and for evaluatively congruent trials. However, crucially, the congruity effect was eliminated and overridden by pseudocontingencies inferred from the stimulus environment. These strategic inferences were further enhanced when the task called for the evaluation of both prime stimuli and target stimuli.
On determining symmetries in inputs of logic circuits

We propose a method for computing maximal sets of symmetric inputs in large circuits, using a test generation procedure for single stuck-at faults. The method is enhanced by heuristics that can be used to identify non-symmetric inputs, and reduce the number of inputs for which test generation has to be carried out. We show the relevance of the problem to input matching for design diagnosis and for technology mapping, and show that the input patterns produced by one of the heuristics can be used for input matching as well. Experimental results demonstrate the effectiveness of the proposed procedures. We also introduce an extended definition of input symmetry that helps in effectively solving the design diagnosis and technology mapping problems. <<ETX>>
Assessment of potential orthodontic mini-implant insertion sites based on anatomical hard tissue parameters: a systematic review.

PURPOSE To estimate the applicability of potential sites for insertion of orthodontic mini-implants (OMIs) by a systematic review of studies that used computed tomography (CT) or cone beam CT to evaluate anatomical bone quality and quantity parameters, such as bone thickness, available space, and bone density. MATERIALS AND METHODS Medline and the Cochrane Database of Systematic Reviews were searched to identify all relevant papers. Several key words were used, such as computerized/computed tomography, mini-implants, and OMIs. The anatomical variables that were assigned in each article to a specific site suggesting it as the ideal or best alternative were assessed separately and evaluated with a scoring system. RESULTS Twenty-two articles were included in the study. The most favorable areas for OMI insertion in the maxilla are proposed between the first and second molars buccally and palatally. The best area in the mandible is also between the first and second molars, both buccally and lingually. In the palate, the paramedian area 3 to 6 mm posterior to and 2 to 9 mm lateral to the incisive foramen was identified as the best site for OMI placement. CONCLUSIONS Despite the heterogeneity of the studies, there was considerable agreement regarding the optimal site for OMI insertion among most studies that investigated anatomical hard tissue parameters based on CT or CBCT data. In this respect, the posterior area from the second premolar to the second molar is the best option for OMI placement in alveolar bone.
Short-term Outcome and Quality of Life of Endoscopically Placed Gastric Balloon and Laparoscopic Adjustable Gastric Band

Background/Aim: A prospective longitudinal study was conducted to describe short-term outcome and quality of life (QOL) of endoscopically placed gastric balloon (EPGB) and laparoscopic adjustable gastric band (LAGB). Materials and Methods: Forty seven consecutive patients with body mass index (BMI) of 42 to 72 kg/m2 were assigned to undergo EPGB (n=17) or LAGB (n=30) between May 2008 and May 2010. The main measured outcomes included weight loss, resolution or improvement of comorbidities, hospital stay, complications and QOL. Results: Patients were followed up for a mean of 14 months. Hospital stay was shorter for EPGB patients (one versus two days, P<0.001). Early postoperative complications recorded in EPGB were minor including nausea and vomiting. No late complications were recorded in the EPGB group. One case of band slippage was reported in the LAGB group and fixed laparoscopically. Percent excess weight loss was less in EPGB compared to LAGB (26.2% versus 44.0%, P=0.004). Resolution or improvement of comorbidities was comparable in both groups. The globally impaired preoperative quality of life showed considerable improvement in both groups. Conclusion: EPGB is a safe and effective approach in short-term management of morbid obesity. Weight loss, resolution of comorbidities and improvement in QOL were comparable between both groups.
Permuting Elements Within Columns of a Matrix in Order to Minimize Maximum Row Sum

We study the problem of permuting the elements within columns of a given m × n matrix A so as to minimize its maximum row sum (sum of the elements in a row). We introduce and analyze an approximation algorithm of greedy type for this NP-complete problem. We prove that our algorithm produces matrices with maximum row sums no more than 3/2 − 1/2m times greater than those found by an optimization rule. Moreover, examples are presented which achieve this relative performance. Thus, our algorithm represents a substantial improvement in that all earlier algorithms have a worst-case performance that is asymptotically twice that of an optimization rule. We verify that our algorithm requires at most O(m2n) time, which is a modest increase over the earlier algorithms requiring Θ(mn log n) time in the worst-case.
A cognitive radar network: Architecture and application to multiplatform radar management

The objective of a cognitive radar network is to optimise radar performance in the highly variable mission environments that current operational systems encounter, while minimising its interference with other systems and its vulnerability to countermeasures such as jamming and anti-radiation missiles. A cognitive radar network may achieve these challenges by fully exploiting the available radar resources, sharing data among network components and taking into account prior environmental and situational knowledge as well as experience accumulated during operations. This knowledge can vary from high level information such as intelligence about the threat to low level information such as clutter maps. This paper presents a cognitive radar network architecture that supports this functionality and the application of (self)-learning methods. In this paper reinforcement learning is used to maximise the survivability of naval surface ships in a littoral scenario by managing the modes of an air surveillance radar.
EXProt - a database for EXPerimentally verified Protein functions

EXProt (database for EXPerimentally verified Protein functions) is a new non-redundant database containing protein sequences for which the function has been experimentally verified. It is a selection of 3976 entries from the Prokaryotes section of the EMBL Nucleotide Sequence Database, Release 66, and 375 entries from the Pseudomonas Community Annotation Project (PseudoCAP). The entries in EXProt all have a unique ID number and provide information about the organism, protein sequence, functional annotation, link to entry in original database, and if known, gene name and link to references in PubMed/Medline. The EXProt web page (http://www.cmbi.nl/EXProt) provides further details of the database and a link to a BLAST search (blastp & blastx) of the database. The EXProt entries are indexed in SRS (http://www.cmbi.nl/srs/) and can be searched by means of keywords. Authors can be reached by email (exprot(cmbi.kun.nl).
Design of a microstrip out-of-phase power divider using shorted-coupled-line transformer

This paper presents a new equal-split power divider with out-of-phase signals between two output ports. The divider comprises two transmission line sections, one resistor, one capacitor, one short stub, one shorted-coupled-line (SCL) transformer, and one quarter-wavelength (λ/4) transformer. The SCL transformer plays three crucial roles. The first and second roles are to improve selectivity of |S21| and isolation of out-of-band, respectively. The third role is to produce 270° phase difference. Thus, the phase difference between SCL and λ/4 transformers can achieve 180° requirement.
Transductive 3D Shape Segmentation using Sparse Reconstruction

We propose a transductive shape segmentation algorithm, which can transfer prior segmentation results in database to new shapes without explicitly specification of prior category information. Our method first partitions an input shape into a set of segmentations as a data preparation, and then a linear integer programming algorithm is used to select segments from them to form the final optimal segmentation. The key idea is to maximize the segment similarity between the segments in the input shape and the segments in database, where the segment similarity is computed through sparse reconstruction error. The segment‐level similarity enables to handle a large amount of shapes with significant topology or shape variations with a small set of segmented example shapes. Experimental results show that our algorithm can generate high quality segmentation and semantic labeling results in the Princeton segmentation benchmark.
Implicit Investigations of Tonal Knowledge in Nonmusician Listeners

Abstract: By mere exposure to musical pieces in everyday life, Western listeners acquire sensitivity to the regularities of the tonal system and to the context dependency of musical sounds. This implicitly acquired tonal knowledge allows nonmusician listeners to perceive relationships among musical events and to develop expectations for future events that then influence the processing of these events. The musical priming paradigm is one method of the indirect investigation of listeners' tonal knowledge. It investigates the influence of a preceding context (with its musical structures and relationships) on the processing of a musical target event, without asking participants for direct evaluations. Behavioral priming data have provided evidence for facilitated processing of musically related events in comparison to unrelated and less‐related events. The sensitivity of implicit investigations is further shown by I.R. , a patient with severe amusia, showing spared implicit knowledge of music. Finally, the priming paradigm allows us to investigate the neural correlates of musical structure processing. Two fMRI studies reported the implication of inferior frontal regions in musical priming, contrasting related and unrelated events, as well as finer structural manipulations contrasting in‐key events.
Unique characterization of conditional distributions in nonlinear filtering

A 'filtered' martingale problem is defined for the problem of estimating a process X from observations of Y, where (X,Y) is Markov. We give conditions on the generator of (X,Y) that imply that the conditional distribution is the unique solution to this filtered martingale problem. We apply this result to prove uniqueness of solutions of the Kushner-Stratonovich and Zakai equations of non-linear filtering.
Multimodality and Deep Learning when Predicting Media Interestingness

This paper summarizes the computational models that Technicolor proposes to predict interestingness of images and videos within the MediaEval 2017 PredictingMedia Interestingness Task. Our systems are based on deep learning architectures and exploit the use of both semantic and multimodal features. Based on the obtained results, we discuss our findings and obtain some scientific perspectives for the task.
Cathepsin expression in oral squamous cell carcinoma: relationship with clinicopathologic factors.

OBJECTIVE Proteases are involved in the invasion and metastasis of carcinoma cells. In vivo, oral carcinoma cells easily invade the bone tissue and metastasize to the submandibular and neck lymph nodes. Cathepsin expression has been shown in some neoplastic tissues and serves as a prognostic indicator. The purpose of this study was to investigate the relationship between clinicopathohistologic grades and cathepsin expressions in oral squamous cell carcinoma and to investigate which cathepsin provides prognostic information for patients with oral carcinoma. STUDY DESIGN Immunohistochemical studies were performed on 78 carcinoma samples with monoclonal antibodies against cathepsins B, H, and L, and a polyclonal antibody against cathepsin D. Serial sections were stained by hematoxylin-eosin staining and classified by Anneroth's classification. Cathepsin B, H, L and D activities of blood serum were determined. Positive results indicative of the presence of cathepsin were investigated to determine any correlation between a particular cathepsin and histologic malignancy grades, tumor cell growth, serum cathepsin activities, and clinical factors. RESULTS Cathepsins B, H, L, and D were positive in every case. Although the labeling indices for cathepsins B (CB-LI), H (CH-LI), and D (CD-LI) for the cancer cases showed significant differences from those of controls, cathepsin L (CL-LI) of cancer cases showed no difference from that of controls (P <.05). A close correlation was found between CD-LI and T categories of TNM classification (P <.05), and between CD-LI and PCNA-LI (P <.05). Furthermore, a close correlation was found between CD-LI and N categories in TNM classification (P <.05). Pathologically, a close correlation was found between CB-LI or CD-LI and the pattern and/or stage of invasion (P <.05). CONCLUSION Cathepsin D and B expression were closely correlated with carcinoma invasion and progression. These proteases may be useful in determining the prognoses of patients with oral carcinoma.