Miracle-dz/UniFAR-FTUs huggingface dataset:
Energy Storage System Control Algorithm by Operating Target Power to Improve Energy Sustainability of Smart Home

As energy issues are emerging around the world, a variety of smart home technologies aimed at realizing zero energy houses are being introduced. Energy storage system (ESS) for smart home energy independence is increasingly gaining interest. However, limitations exist in that most of them are controlled according to time schedules or used in conjunction with photovoltaic (PV) generation systems. In consideration of load usage patterns and PV generation of smart home, this study proposes an ESS control algorithm that uses constant energy of energy network while making maximum use of ESS. Constant energy means that the load consumes a certain amount of power under all conditions, which translates to low variability. The proposed algorithm makes a smart home a load of energy network with low uncertainty and complexity. The simulation results show that the optimal ESS operating target power not only makes the smart home use power constantly from the energy network, but also maximizes utilization of the ESS. In addition, since the smart home is a load that uses constant energy, it has the advantage of being able to operate an efficient energy network from the viewpoint of energy providers.
Compositional Neural Network Language Models for Agglutinative Languages

Continuous space language models (CSLMs) have been proven to be successful in speech recognition. With proper training of the word embeddings, words that are semantically or syntactically related are expected to be mapped to nearby locations in the continuous space. In agglutinative languages, words are made up of concatenation of stems and suffixes and, as a result, compositional modeling is important. However, when trained on word tokens, CSLMs do not explicitly consider this structure. In this paper, we explore compositional modeling of stems and suffixes in a long short-term memory neural network language model. Our proposed models jointly learn distributed representations for stems and endings (concatenation of suffixes) and predict the probability for stem and ending sequences. Experiments on the Turkish Broadcast news transcription task show that further gains on top of a state-of-theart stem-ending-based n-gram language model can be obtained with the proposed models.
Modélisation et contrôle d'une main anthropomorphe actionnée par des tendons antagonistes

Un des freins majeurs au developpement de la manipulation d'objet avec une main robotisee est sans aucun doute leur fragilite. C'est l'une des raisons pour laquelle un systeme bras-main anthropomorphe, extremement robuste, est developpe au centre de robotique et de mecatronique de DLR. Le systeme est unique a la fois par sa complexite, utilisant 52 moteurs et plus de200 capteurs, ainsi que par ses capacites dynamiques. En effet, ce nouveau systeme a la particularite d'etre mecaniquement flexible ce qui offre la possibilite de stocker de l'energie a court terme et remplit ainsi deux fonctions essentielles pour un robot humanoide: les impacts sont filtres et les performances dynamiques sont augmentees.Dans cette these, on se concentre plus particulierement sur la main. Elle dispose de 19 degres de liberte dont chacun est actionne par deux tendons flexibles antagonistes. La rigidite des tendons etant non lineaire il est possible, tout comme peut le faire l'etre humain, de co-contracter les > et donc d'ajuster la rigidite des doigts afin de s'adapter au mieux aux tâches a effectuer. Cependant, cette flexibilite entraine de nouveau defis de modelisation et de controle. L'etat de l'art se concentre majoritairement sur le probleme de la repartition des forces internes ou du controle d'articulation flexible mais peu de travaux considerent les deux problemes simultanement.Le travail presente dans la premiere partie de la these se concentre sur la modelisation de la main et du poignet. Les problematiques specifiques aux systemes actionnes par des tendons, tels que les matrices de couplage et l'estimation du deplacement des articulations a partir du deplacement des tendons, sont etudiees.La seconde partie se concentre sur le controle d'articulations actionnees par des tendons flexibles antagonistes. Les problemes de distribution des forces internes et de correction de la rigidite percue par l'utilisateur sont presentes.Des approches de controle lineaire et non lineaire sont utilisees et des experiences sont realisees pour comparer ces approches. En particulier, il est montre que le >, une methode de controle non lineaire peut etre utilisee et permet d'obtenir le comportement d'impedance souhaite tout en garantissant la stabilite en boucle fermee.
Feasibility of Voluntary Menu Labeling Among Locally Owned Restaurants

In 2007, Tacoma-Pierce County Health Department launched a restaurant menu labeling project called SmartMenu. The objective was to recruit locally owned restaurants to voluntarily post basic nutrition information on their menus or menu boards. Participating restaurants submitted recipes to an independent contractor for nutritional analysis and agreed to post calorie, fat, carbohydrate, and sodium values on new menus within 90 days of receiving results. Vigorous recruitment efforts by the Health Department between June 2007 and September 2008 included free advertising, consultation with a Registered Dietitian, and free nutritional analysis. By the end of 2008, a total of 24 restaurants participated in the program. Significant barriers to participation included infrequent use of standardized recipes, perceived business risk of labeling, and low perceived customer demand for nutrition information. Key program elements, recruitment strategies, and costs are discussed. Results have important implications for future efforts to increase the adoption of menu labeling by locally owned and operated restaurants.
Cytosolic and Endoplasmic Reticulum Ca2+ Concentrations Determine the Extent and the Morphological Type of Apoptosis, Respectively

Abstract: During apoptosis, an increase in cytosolic Ca2+ concentration ([Ca2+]c) accompanies the depletion of endoplasmic reticulum (ER). The actual roles of each of the two events in apoptosis are difficult to understand. In this work, we have modulated the basal [Ca2+]c and the thapsigargin (THG)‐dependent reticular flux (i.e., by chelating extracellular Ca2+ or by modulating intracellular Ca2+ by 3‐aminobenzamide [3‐ABA]). We have found that these treatments alter these Ca2+ parameters in a differential way and, accordingly, affect apoptosis differentially. We have found that the increase in [Ca2+]c is related to the extent of apoptosis, whereas the ER depletion affects the apoptotic nuclear morphology by shifting it towards the cleavage mode.
Modeling the Effect of Periodic Wall Roughness on the Indoor Radio Propagation Channel

A deterministic model based on ray tracing and dealing with periodic roughness is developed, for an indoor radio propagation channel and experimentally validated at a frequency of 10 GHz. Two different scenarios are studied, namely a smooth corridor and a corridor having artificial periodic roughness. The periodic roughness consists of a set of conductive semi-cylinders attached to the corridor sidewalls. Two different antenna setups are considered during the measurements, hornhorn antennas and patch-patch antennas, in transmitter-receiver configurations. Excellent agreement is achieved in terms of the received powers versus distance and the power delay profiles. The signal fading is analyzed. The statistical parameters are also generated, and a good agreement is observed between the simulation and measurement results.
Leitthema : Klinische Studien – Spezifika

The increasing number of approved efficacious therapies for various indications raises the question of whether the inclusion of a placebo group is still justified. In addition, pharmaceutical companies and regulatory agencies acknowledge that it may be sufficient to prove that a new therapy is comparable to an approved reference therapy regarding efficacy and safety in some situations. This becomes especially striking for the approval to market a generic drug. Another, perhaps even more important example is the increasing resistance of bacteria which calls for new antibiotics based on new therapeutic principles without having the claim for better efficacy. In these situations, a comparable efficacy would constitute progress. In the present paper, we discuss the numerous methodological challenges and approaches to overcome these problems that occur when it is not possible or even not wanted to use the classic approach of a randomized placebo-controlled superiority trial. Here, the field of medical biometry, which has proved in the last 25 years to be an integral part of the development of new drugs, demonstrates its suitability as a flexible and scientifically based means to fulfil the requirements resulting from clinical practice. Starting from the fact that statistical methods are not able to prove “equality” of two treatments, “shifted” hyBiometrical methods for the proof of efficacy in regulatory submissions. Non-inferiority in clinical studies potheses are considered and their importance for the different study designs is discussed. We show how the classic hypotheses known from placebo-controlled clinical trials can be embedded in this concept. The implications of this approach for the analysis and interpretation of study results is further discussed. The relevant guidelines of the European and US regulatory agencies are taken into account.
Reducing the Stimulation of CD8+ T Cells during Infection with Intracellular Bacteria Promotes Differentiation Primarily into a Central (CD62LhighCD44high) Subset1

During infection with lymphocytic choriomeningitis virus, CD8+ T cells differentiate rapidly into effectors (CD62LlowCD44high) that differentiate further into the central memory phenotype (CD62LhighCD44high) gradually. To evaluate whether this CD8+ T cell differentiation program operates in all infection models, we evaluated CD8+ T cell differentiation during infection of mice with recombinant intracellular bacteria, Listeria monocytogenes (LM) and Mycobacterium bovis (BCG), expressing OVA. We report that CD8+ T cells primed during infection with the attenuated pathogen BCG-OVA differentiated primarily into the central subset that correlated to reduced attrition of the primed cells subsequently. CD8+ T cells induced by LM-OVA also differentiated into central phenotype cells first, but the cells rapidly converted into effectors in contrast to BCG-OVA. Memory CD8+ T cells induced by both LM-OVA as well as BCG-OVA were functional in that they produced cytokines and proliferated extensively in response to antigenic stimulation after adoptive transfer. During LM-OVA infection, if CD8+ T cells were guided to compete for access to APCs, then they received reduced stimulation that was associated with increased differentiation into the central subset and reduced attrition subsequently. Similar effect was observed when CD8+ T cells encountered APCs selectively during the waning phase of LM-OVA infection. Taken together, our results indicate that the potency of the pathogen can influence the differentiation and fate of CD8+ T cells enormously, and the extent of attrition of primed CD8+ T cells correlates inversely to the early differentiation of CD8+ T cells primarily into the central CD8+ T cell subset.
Active preference learning for generative adversarial networks

Generative Adversarial Networks (GAN) has recently become a popular tool for image generation. The GAN is able to generate a realistic image from the input of a d-dimensional vector. In the past years, it has been applied to many fields such as image search and designing. However, since the relationship between the input vector and the generated image is not clear, one has to manually update the input values many times in order to generate the desired image. In order to alleviate this problem, in this paper, we propose a new human-in-the-loop method to easily generate one's desired images. In the proposed method, Bayesian optimization is used to identify patterns in previously chosen images and reduce the number of trials necessary to get the desired output. We evaluate the utility of our method through crowd-sourced experiments.
The impact of Total Quality Management on organisational performance.

The concept of Total Quality Management (TQM) has been developed as a result of intense global competition; empirical studies show that TQM has considerable impact on business performance. Indeed, business practice strongly admit and adhere TQM as a management tool for improving organizational performance. Predominantly, TQM is accepted as a cornerstone for organizational excellence and prosperity, as its prime means are continuous development, systematic control, customer satisfaction and monitoring of the processes and many others that are targeted to maintain competitiveness and efficiency. Importantly, it is highly desired that TQM could become a management philosophy in the organization that is keenly adopted by managers and employees as a facilitating tool and engine for growth. The purpose of this paper is to examine this issue and propose the relationship between TQM practices and organizational performance as a whole. Initially, organizational performance will be characterized by competitive advantage, efficiency and financial performance of the company. Hopefully, the results of this paper will inspire the interested companies in TQM model and present in-depth knowledge of TQM theory and its impacts on business outcomes. Moreover, some managerial implications and scope for future study will be offered at the end. Nevertheless, if applied wisely, TQM constitute the management system that covers all the aspects of the business process that is consequently aimed to achieve organizational excellence and prosperity.
Physique Statistique et Géométrie

Cette these se compose de deux parties. Une premiere partie est dediee a l'etude de phenomenes de diffusions dans des geometries non triviales. Je presente tout d'abord un travail sur les effets des irregularites de la geometrie d'une surface sur un mouvement brownien galileen evoluant sur cette surface. Ce probleme est susceptible d'applications en biologie, notamment dans la modelisation des phenomenes de diffusions laterales sur des interfaces. J'expose ensuite des travaux realises sur des processus stochastiques relativistes. J'introduis d'une part des modeles simples de diffusion dans un univers en expansionet presente des relations de fluctuation-dissipation verifiees par ces modeles. J'expose d'autre part une approche unifiee des differents processus stochastiques relativistes existant dans la litterature, a savoir, le ROUP, le processus de Franchi-Le~Jan et le processus de Dunkel-Hanggi. Dans une seconde partie, je presente deux applications de la recente theorie champ moyen de la relativite generale. La theorie a ete appliquee a un trou noir de Schwarzschild et a un trou noir de Reisner-Nordstrom extreme. Les caracteristiques de l'espace-temps moyen obtenu dans chacun de ces deux cas sont presentees. Les resultats sont mis en relation avec des observations de trous noirs astrophysiques et avec des observations cosmologiques. Les effets de la moyennisation sur les proprietes thermodynamiques de ces trous noirs sont egalement etudies.
Discrimination of the Odor of Stressed Rats

Albino rats can reliably distinguish between the odors of stressed and unstressed rats. Five animals learned to interrupt an ongoing response when air from the cages of stressed rats was introduced into the test compartment, and to continue responding when air from unstressed rats was introduced. The discrimination does not seem to depend on recognition of odors of individual rats.
Mapping of Domains on HIV Envelope Protein Mediating Association with Calnexin and Protein-disulfide Isomerase*

The cell catalysts calnexin (CNX) and protein-disulfide isomerase (PDI) cooperate in establishing the disulfide bonding of the HIV envelope (Env) glycoprotein. Following HIV binding to lymphocytes, cell-surface PDI also reduces Env to induce the fusogenic conformation. We sought to define the contact points between Env and these catalysts to illustrate their potential as therapeutic targets. In lysates of Env-expressing cells, 15% of the gp160 precursor, but not gp120, coprecipitated with CNX, whereas only 0.25% of gp160 and gp120 coprecipitated with PDI. Under in vitro conditions, which mimic the Env/PDI interaction during virus/cell contact, PDI readily associated with Env. The domains of Env interacting in cellulo with CNX or in vitro with PDI were then determined using anti-Env antibodies whose binding site was occluded by CNX or PDI. Antibodies against domains V1/V2, C2, and the C terminus of V3 did not bind CNX-associated Env, whereas those against C1, V1/V2, and the CD4-binding domain did not react with PDI-associated Env. In addition, a mixture of the latter antibodies interfered with PDI-mediated Env reduction. Thus, Env interacts with intracellular CNX and extracellular PDI via discrete, largely nonoverlapping, regions. The sites of interaction explain the mode of action of compounds that target these two catalysts and may enable the design of further new competitive agents.
The converse effects of speed and gravity on the energetics of walking and running

The energetic cost of transport for walking is highly sensitive to speed but relatively insensitive to changes in gravity level. Conversely, the cost of transport for running is highly sensitive to gravity level but not much to speed. Gait optimization with a minimally constrained bipedal model predicts a similar differential energetic response for walking and running even though the same model parameters and cost function are used for both gaits. This challenges previous assertions that the converse energetic responses are due to fundamentally different energy saving mechanisms in each gait. Our results suggest that energetics of both gaits are highly influenced by dissipative losses occurring as leg forces abruptly alter the center of mass path. The observed difference in energetic consequence of the performance condition in each gait is due to the effect the movement strategy of each gait has on the dissipative loss. The optimization model predictions are tested directly by measuring metabolic cost of human subjects walking and running at different speeds in normal and reduced gravity using a novel reduced gravity simulation apparatus. The optimization model also predicts other, sometimes subtle, aspects of gait such as step length changes. This is also directly tested in order to assess the fidelity of the model’s more nuanced predictions.
Cushing's Syndrome

IN A STUDY of cases of Cushing's syndrome at the Los Angeles County General Hospital for the period 1949-1958, it soon became apparent that diagnosis and management, as yet not standardized, had changed considerably during this period. Newer diagnostic procedures, and availability of specific hormonal replacement therapy both aid in early decisions regarding care of individual patients and eliminate the hopelessness which the diagnosis of Cushing's syndrome formerly conveyed; but these changes have developed so rapidly that the previous ultraconservative approach persists. Since the brilliant observations of this symptom complex by Cushing in 1912,6 and his case reports of "pituitary basophilism" in 1932,7,8 new concepts have arisen. It is interesting to note that in a recent paper in the Chinese Medical Journal, Wu and Wang give prior credit to Itsenko, stating that in 1925 he had pointed out changes in the mesencephalon, pituitary and adrenals associated with the syndrome.34 They called the condition Itsenko-Cushing disease. Despite reports of cases in which the syndrome was associated with adrenal disease, it was long felt to be primary in the pituitary. Present-day observers have come to accept the adrenals as the primary source of the steroid hormones that produce the syndrome, whereas Cushing's disease is the term used to indicate those cases in which adrenal hyperfunction appears to be secondary to basophilic changes of the pituitary. Many cases of the syndrome have now been reported in which no evidence of pituitary disease can be found; which do not respond to the destruction or suppression of the pituitary, but respond to adequate ablation of the adrenal cortex. It is well known that both corticotropin and adrenal steroids can produce the syndrome29 (acquired Cushing's syndrome). Whether the process is initiated in the hypothalamus, the pituitary or the adrenal cortex may be controversial, but there is now no doubt that the symptoms and signs in a given patient are due to adrenal cortical hyperfunction, and in this communication the latter term is used to indicate Cushing's syndrome. The case records of 125 patients at the Los Angeles County General Hospital in whom Cushing's
Sustainability research in the hotel industry: Past, present, and future

ABSTRACT Sustainability continues as one of the most commonly discussed trends within the hotel industry. An extensive comprehensive review of previous literature identified 128 articles focusing on sustainability within the industry: management, energy conservation, and education. The studies were broken down into seven categories, allowing for identification of trends. Researchers’ review of the articles identified the most dominant contributors to academic research and the publications which most prominently feature research on the subjects relevant to hotel sustainability. The balanced scorecard categorized research based on five perspectives, identifying the most dominant research on sustainability within the hotel industry. The current study illustrates literature gaps showing what areas research is lacking, allowing future researchers to fill in the holes with future studies.
Occurrence and Detection of Iron-deficiency Anemia in Infants and Toddlers

Infants and toddlers are particularly vulnerable to developing iron deficiency, which can cause irreversible deficits in neurodevelopment. Children at highest risk include premature and low birth weight infants, those who are fed cow's milk rather than breast milk or formula prior to age one, and those who drink large amounts of cow's milk as toddlers. It is important to detect iron deficiency before it becomes frank anemia through the use of appropriate laboratory tests. Hemoglobin or hematocrit testing, at around age one, has been the usual screening test. These tests, however, do not become abnormally low until frank anemia has developed. Over the past decade, research has shown the assay for reticulocyte hemoglobin content to be a much earlier indicator of iron deficiency. This article provides an overview of the epidemiology, occurrence, and detection of iron deficiency and iron deficiency anemia in young children as well as a comparison of the utility of various laboratory tests. Infants and toddlers are particularly vulnerable to the effects of anemia due to the rapid growth and development of the brain and the rest of the body from birth to age three. Pre-term and/or low birth weight infants are even more vulnerable. Although it is more common in developing countries due to nutritional deficiencies and chronic blood loss from parasitic infections,1 iron-deficiency anemia (IDA) is the most prevalent anemia found in infants, toddlers and child-bearing age females in the United States.2 Therefore, it is important to detect a state of iron deficiency in these… ABBREVIATIONS: CHr = hemoglobin content in reticulocytes; dL = deciliter; FEP/ZPP = free/zinc erythropoietic protoporphyrin; fL = femtoliters; g = gram; ID = iron deficiency; IDA = iron-deficiency anemia; L = liter; MCH = mean cell hemoglobin; MCV = mean corpuscular volume; mg = milligrams; ng = nanograms; NRBC = nucleated red blood cells; oz = ounces; pg = picograms; RDW = red blood cell distribution width; Ret He = reticulocyte hemoglobin; SF = serum ferritin; sTfR = serum transferrin receptor; TIBC = total iron binding capacity; TS = transferrin saturation; ug = micrograms.