Miracle-dz/UniFAR-FTUs huggingface dataset:
Robust and secure PCQP Technique of Location Based Service to Improve K-NN Search Using Secret Circular Shift

Location-based services (LBS) are a general class of computer program-level services that use location data to control features. As such LBS is an information service and has a number of uses in social networking today as an entertainment service, which is accessible with mobile devices through the mobile network and which uses information on the geographical position of the mobile device. This has become more and more important with the expansion of the smartphone and tablet markets as well. LBS are used in a variety of contexts, such as health, indoor object search, entertainment, work, personal life, etc. Privacy issues (including security, privacy, and trust) in mobile social networks are concerned about the condition of being protected against different types of failure, damage, error, accidents, harm or any other non-desirable event, while mobile carriers contact each other in mobile and cloud environments. The rationale behind this work paper is to investigate the threats to privacy that come up while users not have a good judgment of privacy consciousness. A successful privacy-preserving LBS must be secure and provide accurate query results. In this paper, we propose a private circular query protocol (PCQP) to deal with the privacy and the accuracy issues of privacy-preserving LBS. The protocol consists of a space filling curve and a public-key homomorphic cryptosystem.First, we connect the points of interest (POIs) on a map to form a circular structure with the aid of a Moore curve. And then the homomorphism of Paillier cryptosystem is used to perform secret circular shifts of POI-related information (POI-info), stored on the server side. Lokireddi Chenna Reddy M.Tech Student , Computer Science Engineering Department, Sir C R Reddy College of Engineering. Chalasani Rama Devi Assistant Professor, Computer Science Engineering Department, Sir C R Reddy College of Engineering. Since the POI-info after shifting and the amount of shifts are encrypted, LBS providers (e.g., servers) have no knowledge about the user’s location during the query process. The protocol can resist correlation attack and support a multiuser scenario as long as the predescribed secret circular shift is performed before each query; in other words, the robustness of the proposed protocol is the same as that of a one-time pad encryption scheme.
Neural mechanisms of cognitive memory

It is my great honor to be here for the award of the 2003 Keio Medical Science Prize. I express my gratitude to Keio University and Dr. Mitsunada Sakaguchi. Knowledge or experiences are voluntarily recalled from memory by reactivation of their neural representations in the cerebral association cortex. Four questions are central in understanding this process: (1) Where in the brain is the mnemonic representation of objects localized? And how is it organized? (2) How is the representation created and what is the morphological and molecular basis of neural circuit reorganization? (3) Which neural circuits enable the reactivation of the representation in memory retrieval? (4) What is the neural basis of cognitive control in memory retrieval and in meta-memory judgment? Clinical studies in humans have suggested that longterm declarative memory is stored in the neocortical association area that is also engaged in sensory perception (for review, see Miyashita, 1993,1 Miyashita & Hayashi, 20002). When electrical stimulation was applied via cortical surface electrodes placed on the temporal lobe during neurosurgery under local anesthesia, epileptic patients sometimes reported recollection of past perceptual experiences (Penfield & Perot, 1963),3 suggesting that artificial electrical input to the putative memory storehouse might reactivate the ‘‘brain’s record of auditory and visual experience’’. Recent experimental studies in humans and non-human primates moved beyond those classical clinical observations and revealed clearer and more solid views on the issues, particularly regarding the memory system of visual objects. In this lecture, I will first describe how memory engrams are organized in the cerebral cortex, focusing on the neural representation of semantically linked symbols/objects. I will then discuss how memory engrams are activated, highlighting two different retrieval processes, ‘active’ and ‘automatic’. Finally, I will show you our recent attempts to clarify the neural basis of a metamemory system, which supervises the retrieval process and exerts cognitive control.
A Bluetooth-based minimum infrastructure home localisation system

Indoor location tracking is a function best suited to wireless LAN devices. This generally precludes it from home use in isolated rural areas, where WLAN is a rare commodity. We propose an affordable localisation system which can be implemented using a variety of Bluetooth enabled mobile phones. This permits the incorporation of cellular network signal measurements as well as Bluetooth link measurements into the localisation framework. This paper presents a Hidden Markov Model localisation method, utilising the Viterbi algorithm, which enables single Bluetooth access point localisation. The improvement of accuracy this presents over a Naive Bayes classifier is illustrated, along with the optimal method of obtaining training data.
Two Cellobiohydrolase-Encoding Genes from Aspergillus niger Require d-Xylose and the Xylanolytic Transcriptional Activator XlnR for Their Expression

ABSTRACT Two cellobiohydrolase-encoding genes, cbhA andcbhB, have been isolated from the filamentous fungusAspergillus niger. The deduced amino acid sequence shows that CbhB has a modular structure consisting of a fungus-type cellulose-binding domain (CBD) and a catalytic domain separated by a Pro/Ser/Thr-rich linker peptide. CbhA consists only of a catalytic domain and lacks a CBD and linker peptide. Both proteins are homologous to fungal cellobiohydrolases in family 7 of the glycosyl hydrolases. Northern blot analysis showed that the transcription of thecbhA and cbhB genes is induced byd-xylose but not by sophorose and, in addition, requires the xylanolytic transcriptional activator XlnR.
Molecular Cloning and Tissue-Specific Expression of Toll-Like Receptor 5 Gene from Turkeys

SUMMARY. Toll-like receptors (TLRs), a family of transmembrane and cytosolic proteins, detect microbial patterns, initiating innate immune responses in various organisms. Although they are abundant, genetic characterization and functional differences of TLRs in economically important avian species such as chickens and turkeys have not been investigated in detail. In this study, the putative TLR5 coding region from turkey genome was sequenced, and its homology to other vertebrate species was analyzed. Secondary structure analysis revealed protein motifs typical of the chicken TLR5 protein structure, with 97% amino acid identity between them. mRNA expression profiling in adult turkeys revealed abundant TLR5 expression in a broad range of tissues. Stimulation with the TLR5 ligand flagellin resulted in the production of the inflammatory mediators interleukin (IL)-1&bgr;, IL-6, and nitric oxide in peripheral blood mononuclear cells. To our knowledge, this is the first complete turkey TLR5 coding DNA sequence reported in sequence databases.
Temperature influence on embryonic development of Anopheles albitarsis and Anopheles aquasalis.

Temperature influence on the embryonic development of Anopheles aquasalis and An. albitarsis was investigated. At 26 degrees C, 75% and 60% of respectively An. aquasalis and An. albitarsis eggs hatched, with one peak of eclosion, between the 2nd and 3rd day after oviposition. At 20 +/- 2 degrees C, around 66-70% of An. aquasalis eggs hatched, with one eclosion peak, on the 5th day. On the other hand, An. albitarsis eclosion at 21+/- 2 degrees C decreased to 10-22%, with two eclosion peaks, on the 4th-5th day and on the 9th-12th day. These data indicate a stronger temperature influence over An.albitarsis than over An. aquasalis embryos.
Ghost Map: Proving Software Correctness using Games

A large amount of intellectual effort is expended every day in the play of on-line games. It would be extremely valuable if one could create a system to harness this intellectual effort for practical purposes. In this paper, we discuss a new crowd-sourced, on-line game, called Ghost Map that presents players with arcade-style puzzles to solve. The puzzles in Ghost Map are generated from a formal analysis of the correctness of a software program. In our approach, a puzzle is generated for each potential flaw in the software and the crowd can produce a formal proof of the software’s correctness by solving all the corresponding puzzles. Creating a crowdsourced game entails many challenges, and we introduce some of the lessons we learned in designing and deploying our game, with an emphasis on the challenges in producing real-time client gameplay that interacts with a server-based verification engine. Finally, we discuss our planned next steps, including extending Ghost Map’s ability to handle more complex software and improving the game mechanics to enable players to bring additional skills and intuitions to bear on those more complex problems. Keywords-games; static analyses; formal verification; crowd souring; games; model checking.
A method for automatic extraction of multiword units representing business aspects from user reviews

The article describes a semi‐supervised approach to extracting multiword aspects of user‐written reviews that belong to a given category. The method starts with a small set of seed words, representing the target category, and calculates distributional similarity between the candidate and seed words. We compare 3 distributional similarity measures (Lin's, Weeds's, and balAPinc), and a document retrieval function, BM25, adapted as a word similarity measure. We then introduce a method for identifying multiword aspects by using a combination of syntactic rules and a co‐occurrence association measure. Finally, we describe a method for ranking multiword aspects by the likelihood of belonging to the target aspect category. The task used for evaluation is extraction of restaurant dish names from a corpus of restaurant reviews.
The Porphyromonas gingivalis O antigen is required for inhibition of apoptosis in gingival epithelial cells following bacterial infection.

BACKGROUND AND OBJECTIVE Porphyromonas gingivalis infection induces apoptosis inhibition in gingival epithelial cells; however, it is not fully understood which bacterial effectors are involved in this process. The aim of this study is to evaluate whether the P. gingivalis lipopolysaccharide (LPS), specifically the O-antigen region, affects adherence, invasion, viability and apoptosis of gingival epithelial cells. MATERIAL AND METHODS Gingival epithelial cells (OKF6/TERT2 line) were infected by different freshly prepared P. gingivalis clinical isolates, obtained from subjects with chronic periodontitis (CP3 and CP4) and healthy individuals (H1 and H3). Periodontitis and healthy isolates show differences in O-antigen production, as healthy isolates lack the O-antigen region. In addition, cells were infected by a site-specific mutant lacking the O-antigen portion. After 24 h postinfection, cell proliferation, viability and apoptosis were evaluated by Trypan blue, MTS and annexin V assays, respectively. Bacterial invasion, adhesion and proliferation were measured by gentamicin/metronidazole protection assays. Finally, toll-like receptor (TLR)2 and TLR4 mRNA expression was evaluated by quantitative reverse transcription-polymerase chain reaction. Statistical analysis was performed using ANOVA, Tukey's or Dunnett's tests (p < 0.05). RESULTS At 24 h postinfection, strains lacking the O-antigen region (healthy isolates and O-antigen ligase-deficient strain) were unable to increase proliferation and viability, or decrease apoptosis as compared with strains producing intact LPS (periodontitis isolates and reference strain). However, the presence of the O-antigen neither contributed to changes in the ability of the bacteria to adhere to or invade cells, nor to intracellular survival. The presence of O-antigen also increased the expression of TLR4 (nearly sixfold), which correlated with inhibition of apoptosis. CONCLUSION The O-antigen region of P. gingivalis LPS is required to increase gingival epithelial cell viability upon infection by bacteria and this increase is attributable to a reduction in apoptosis. Moreover, although bacterial internalization is required, the effects observed are not due to alterations in P. gingivalis adherence, invasion or intracellular survival. Interestingly, inhibition of apoptosis correlates with increased TLR4 expression, suggesting a role for TLR4 in this process.
Analysis of the adaptor function of the LIM domain‐containing protein FHL2 using an affinity chromatography approach

Containing four LIM domains and an N‐terminal half LIM domain, FHL2 has been predicted to have an adaptor function in the formation of higher order molecular complexes in the nucleus and the cytoplasm of cells. We expressed recombinant FHL2 in insect cells using the baculovirus system and used it to isolate direct or indirect interaction partners from the cytosolic fraction of fibroblasts by affinity chromatography. These were identified by their peptide mass fingerprints using MALDI‐TOF mass spectrometry. Cytoskeleton‐associated proteins present among the bound proteins were shown to co‐localise with FHL2 in cell lamellipodia by indirect immunofluorescence staining. © 2004 Wiley‐Liss, Inc.
Revisión del Estado del Arte en Modelado del Order Fufillment Process mediante Sistemas Multi-Agente

El proceso de cumplimiento de pedidos (Order Fufillment Process u OFP) es de vital importancia en cualquier empresa o cadena de suministro, ya que la satisfaccion del cliente depende en gran medida de su correcto funcionamiento. Sin embargo su integracion en una cadena de suministro es compleja, debido principalmente al gran numero de entidades que la componen. En este articulo se hace una revision del estado del arte en modelado del OFP mediante sistemas multi-agente, clasificando los articulos en funcion de los niveles de la cadena de suministro modelada, el rol que juegan los agentes y el grado de desarrollo de las aportaciones.
RELATIONSHIP BETWEEN PREMACULAR CORTICAL VITREOUS DEFECTS AND IDIOPATHIC PREMACULAR FIBROSIS

Purpose: To investigate the relationship between the defect in the premacular cortical vitreous detached from the retina and the development of idiopathic premacular fibrosis. Methods: One hundred six consecutive patients (106 eyes) with posterior vitreous detachment but no other ocular disorders were prospectively studied. All follow‐up periods were longer than 6 months. The vitreous condition was studied using an aspherical, +58.6‐diopter preset lens with a slit‐lamp. Results: The detached premacular cortical vitreous was a continuous, unbroken sheet in 93 (88%) of the 106 eyes; in 13 (12%) eyes, the detached premacular cortical vitreous had an oval or round defect ranging from 4 to 7 disc diameters over the macula. At the study's conclusion, 36 (34%) of the 106 eyes had idiopathic premacular fibrosis; 70 (66%) eyes did not. The defect in the detached premacular cortical vitreous was observed in 9 (25%) of the 36 eyes that eventually developed idiopathic premacular fibrosis and in 4 (6%) of the 70 eyes that did not undergo such development. The incidence of the defect in the detached premacular cortical vitreous was significantly higher in eyes with idiopathic premacular fibrosis than in eyes without (P = 0.011). Nine (69%) of thirteen eyes with the defect in the detached premacular cortical vitreous developed premacular fibrosis, whereas only 25% of eyes without the defect developed it. Twenty‐seven (75%) of thirty‐six eyes with premacular fibrosis did not have a defect in the detached premacular cortical vitreous. Conclusions: The defect in the detached premacular cortical vitreous probably occurs because the premacular cortical vitreous remains attached to the internal limiting lamina when a posterior vitreous detachment develops. The vitreous that remains attached to the macula may be related to the development of idiopathic premacular fibrosis.
The function of laryngeal muscles in regulating fundamental frequency and intensity of phonation.

Electromyographic recordings of the activity of selected intrinsic laryngeal muscles of a professional singer and several untrained subjects were made during both singing and speech. The mechanism regulating fundamental frequency and intensity differed for different registers and fundamental frequencies. For low‐pitched phonation in chest register, laryngeal muscles contributed pronouncedly to changes in fundamental frequency and intensity; whereas for high‐pitched phonation in falsetto register, their contribution was less. Therefore, one can presume that for high falsetto the air‐flow rate was the dominant factor regulating fundamental frequency and intensity. There was no essential difference of the muscular activity patterns between speech and singing in chest register as far as regulation of fundamental frequency and intensity of voice is concerned. [This research was partially supported by the National Institutes of Health, U. S. Department of Health, Education, and Welfare, and the Office of Naval .
Host country experience, institutional distance and location choice of Chinese MNEs

Purpose The conventional wisdom suggests that the lack of prior host country-specific experience and a higher institutional distance deter multinational enterprises (MNEs) from entering a foreign country. However, past studies report that Chinese MNEs show an unconventional risk-taking behavior choosing foreign locations, where they have no prior experience or there is an increased institutional distance. Drawing on the institutional theory, the purpose of this paper is to argue that Chinese Government official visits to the host country may act as a risk-reduction device, thus providing an explanation for such an unconventional behavior. Design/methodology/approach The authors develop two hypotheses regarding how Chinese Government official visits moderate the impact of host country-specific experience and institutional distance on the location choice of Chinese MNEs. The authors test the hypotheses using a sample of investment location decisions by Chinese MNEs in Latin America. Findings The authors find that government official visits mitigate the lack of firm’s prior host country experience. However, only high-level government visits reduce institutional distance. Originality/value The authors contribute to the international business literature by analyzing how home country government diplomatic activities may pave the way of host country institutional environment for foreign MNEs from that home country. In addition, the authors provide an additional explanation for the unconventional risk-taking behavior of Chinese MNEs. Finally, the authors also contribute to a better understanding of the decision-making process of emerging-market MNEs entering other emerging economies.
A brief history of the cisternal progression–maturation model

This paper represents my view of the development of the concept of cisternal progression–maturation over the last few decades, to date. It is not meant to be particularly technical or exhaustive, and it is not addressed only to the specialist. For more detailed information, readers are referred to the key references. The goal is mainly to stimulate discussion, for which the cisternal maturation model appears to be a very apt subject. Indeed, perhaps more than other models in biology, cisternal maturation has been accompanied from the beginning by a number of controversies. The reason for this is not completely clear to me. It might be because the model addresses issues at the historic core of modern cell biology; or because it challenges long-established views; or perhaps it is because its relevance actually goes beyond the field of intra-Golgi trafficking, as it might also apply to other trafficking steps (for instance, from early to late endosomes) 1,2 and it gives rise to the concept of dynamic compartment identity, 3 which is of broad relevance in cell biology. And last, but not least, the debate has suffered from uncertainties that are due to technical reasons: a few key questions cannot be addressed as directly as we would like, simply because today’s microscopy imaging technologies do not yet possess the required resolution power (see below).
The Impact of User Behaviours on the Socialisation Process in Enterprise Social Networks

The success of teams in enterprise social networks (ESN) is of high importance in today’s project-based and digitised work environments. In this context, onboarding of new hires or allocated team members means the adoption of group characteristics and behaviours. Studies identified cohesion and trust as part of the socialisation process and found communication behaviours that facilitate socialisation. ESN not only enable efficient communication or relationship building, they also make the socialisation processes visible and analysable. In this paper, we propose to use metrics from social network analysis (e.g. extraversion, openness and proactiveness) to operationalise communication behaviours identified as positive for socialisation. First evaluations with two ESN data sets in OLS, beta regression and multilevel models sparsely support the influence on closeness, which we expect to reflect the level of group integration.
Stanford-Binet, Fourth Edition and the Wisc—R for Children in the Lower Range of Intelligence

The Stanford-Binet IV and the WISC—R were administered to 30 children, ages 8 to 15 yr. , whose scores were in the range of mild mental retardation. The mean interval between testings was 7 mo. The correlation was . 83, with a median difference of 4 points. The WISC—R mean IQ was significantly lower than the Stanford-Binet-IV Composite mean score for the group. The disparity in scores points to the need to evaluate measures of intelligence together with other indices of functioning in decision-making for mildly retarded children.
Breaking down barriers to identify hemorrhagic transformation in ischemic stroke

Hemorrhagic transformation (HT) is a major complication in ischemic stroke, associated with increased morbidity and mortality. Identifying ischemic stroke patients at risk of HT could have substantial clinical implications, especially in the setting of thrombolytic therapy. Acute stroke patients at very high risk for HT could foreseeably have alternative treatment, such as a modified dose of thrombolytic agent or coadministration of a second agent able to reduce HT risk. In this issue of Neurology ®, Kazmierski et al.1 sought to predict clinical deterioration due to HT in ischemic stroke by measurements of proteins in blood. A total of 458 stroke patients were enrolled in their study, 85 of whom experienced clinical deterioration, and 33 of whom had HT. Stroke patients who developed HT had increased fasting glucose and decreased platelet count compared to those …
Faktor determinan pemilihan auditor eksternal yang berkualitas

The purpose of this research is to analyze the impact of corporate governance mechanism, company's complexity, demand of the external financing and leverage towards the selection of external auditors who can provide high quality audit in Indonesia. This research also uses company's size, foreign ownership and family ownership as control variables. Hypothesis testing is carried out by using logistic regression model using 203 observation with the sample taken from listed companies on the Indonesia Stock Exchange in 2007 except bank and other financial institutions. This study concludes that corporate governance mechanism increases the probability of selecting external auditirs who can provide high quality unit. Company's complexity has a significant influence towards the selection of external auditors although it has a negative correlation leverage do not have any influence on the selection of the external auitors with high quality audit.