Miracle-dz/UniFAR-FTUs huggingface dataset:
Hippocampal slow waves. Distribution and phase relationships in the course of approach learning.

The functions of the temporal lobe, and its preponderant role in the integrative aspects of social behavior, are well known (Bucy and Kluver, 13 1939) and have been the subject of recent reviews (Adey, 2 1959; Baldwin and Bailey, 8 1958). To some extent, physiological dissection of the picture of "psychic blindness" characterizing the complete bilateral temporal lobectomy has been possible with more limited resections, with aspects of hypersexuality, loss of memory, taming, and exaggerated rage responses, each reported as the dominant aspect of a variety of limited resections in man and animals (Adey, 1 1958; Bard and Mountcastle, 10 1948; Green, Clemente, and de Groot, 24 1958; Schreiner and Kling, 45 1953; Scoville and Milner, 46 1957). Historically, the limbic lobe, set as a ring of cortex at the medial margin of the hemisphere, has been described as a somatic integrating center concerned with the integration of somatic influxes
Parents' and therapists' perceptions of the content of the Manual Ability Classification System, MACS

Abstract The Manual Ability Classification System (MACS) is a newly developed five-level classification that describes how children with cerebral palsy (CP) use their hands when handling objects in daily life. Since the MACS level is to be determined by asking the parents or someone else who knows the child well, it is important that the classification is meaningful and easy to understand. The aim of this study was to investigate the content validity based on parents' and therapists' descriptions of the children's ability to use their hands in daily manual tasks. Twenty-five children were represented by a parent and a therapist. After a short presentation of MACS, the respondents rated the child's MACS level. Subsequently, in a short interview, they described their thoughts about the child's ability, the classification, and the scoring process. Parents and therapists found that MACS gives a good description of how children with CP use their hands in daily activities. They found the differences between the five levels meaningful and generally easy to determine. A unique description of the children's ability at each level confirmed the validity. This provided evidence which strengthened the content validity of MACS in a descriptive way. Additional information complementing the existing leaflet could facilitate the scoring process.
Staphylococcal accessory regulator (sar) in conjunction with agr contributes to Staphylococcus aureus virulence in endophthalmitis

Previous studies showed that an agr mutant strain of Staphylococcus aureus was partially attenuated in virulence compared to a parental strain in experimental endophthalmitis. The purpose of this study was to determine whether the sar locus, either alone or through interactions with agr, contributes to the regulation of virulence in S. aureus endophthalmitis. Experimental endophthalmitis was established by the midvitreous injection of approximately 30 CFU of S. aureus RN6390 or the isogenic attenuated strains RN6911 (agr mutant), ALC136 (sar mutant), and ALC135 (agr sar double mutant). Unexpectedly, the rate of reduction in electroretinographic B-wave amplitude in eyes infected with strain ALC136 (sar mutant) was not significantly different from the parental strain on postinfection day (PID) 5 (10% retention). In contrast, ALC135 (agr sar double mutant)-infected eyes retained 73% of preoperative B-wave amplitude on PID 5. Therefore, unlike agr, a mutation in the sar locus alone does not alter the overall virulence of wild-type S. aureus in experimental endophthalmitis. However, the combined effect of insertional mutations in both the sar and agr global regulators leads to near-complete attenuation of virulence.
An Orthogonal Global Task Coordinate Frame for Contouring Control of Biaxial Systems

Recent research on the coordinated control of biaxial machines for precise contour following has been using various locally defined task coordinate frames (LTCF) “attached” to the desired contour to approximately calculate the contour error for feedback controller designs. Contour error, by definition, is a geometrical quantity depending on the shape of the desired contour only and has nothing to do with the desired motion on the contour. As such, all those moving LTCF-based algorithms have to make the assumptions that the position tracking errors are much smaller than the radius of curvature of the desired contour and the calculated contour error is only an approximation of actual contour error. In contrast, this paper presents an orthogonal global task coordinate frame (GTCF) in which the calculation of contour error is exact to the first-order approximation of the actual contour error, no matter how large the position tracking errors would be. A systematic way to construct curvilinear coordinates of the proposed GTCF using any description of the geometry of the desired contour in a two-dimensional space is also given. Contouring control of a linear motor driven biaxial high-speed industrial gantry is then used as a case study. A simplistic direct adaptive robust controller (ARC) is constructed to deal with the effect of strong coupling of the system dynamics in the task space in addition to modeling uncertainties. The proposed GTCF-based ARC algorithm, along with the traditional LTCF-based ARC ones, are implemented and comparative experimental results are presented. The results validate the effectiveness of the proposed GTCF approach for free-form contouring control with large curvatures and arbitrary position tracking errors and confirm the excellent contouring performance of the proposed approach in general.
Synthesis of nanoscopic optical fibers using lipid membranes as templates.

High-aspect-ratio, monocryst. Cd chloride nanowires doped with fluorescent CdS nanoparticles were synthesized using planar lipid membranes as templates. Cd2+ ions bound to the lipid bilayers (a) are released at low pH to the nanometer-sized, interlamellar H2O films (b) where the sudden increase in concn. gives nanowires (c) that show excellent light-waveguiding properties. [on SciFinder (R)]
Implementation and validation of probabilistic models of the anterior longitudinal ligament and posterior longitudinal ligament of the cervical spine

The objective of this investigation was to develop probabilistic finite element (FE) models of the anterior longitudinal ligament (ALL) and posterior longitudinal ligament (PLL) of the cervical spine that incorporate the natural variability of biological specimens. In addition to the model development, a rigorous validation methodology was developed to quantify model performance. Experimental data for the geometry and dynamic properties of the ALL and PLL were used to create probabilistic FE models capable of predicting not only the mean dynamic relaxation response but also the observed experimental variation of that response. The probabilistic FE model uses a quasilinear viscoelastic material constitutive model to capture the time-dependent behaviour of the ligaments. The probabilistic analysis approach yields a statistical distribution for the model-predicted response at each time point rather than a single deterministic quantity (e.g. ligament force) and that response can be statistically compared to experimental data for validation. A quantitative metric that compares the cumulative distribution functions of the experimental data and model response is computed for both the ALL and PLL throughout the time histories and is used to quantify model performance.
Impact of PWM methods and load configuration in the design of intercell transformers used in parallel three-phase inverters

Interleaving techniques applied to the parallel association of converters provide the reduction of the output current ripple and the increase of its frequency, leading to a reduction of the associated filters. The best way of paralleling commutation cells is by means of InterCell Transformers (ICT). The design of such special magnetic components strongly depends on the magnetic flux flowing through their core. This flux is modified by different PWM methods if ICTs are used in three-phase systems. The main objective of the paper is to show how different PWM methods (related to the carrier disposition and also to zero sequence signal injection) influence the flux inside ICTs used in different topologies of three-phase systems. In addition, the most popular PWM methods are compared in order to find the best ones regarding the flux in the ICT. Experimental results validate the analysis presented in this work as well as the reduction on the ICT flux provided by the optimal zero sequence signals.
Spatiotemporal changes of slow wave activities before and after 14 Hz/12 Hz sleep spindles during stage 2 sleep

The present study examined the spatiotemporal changes of slow wave (delta and theta bands) activities before and after 14 Hz/12 Hz sleep spindles during stage 2 sleep, using topographic mapping of electroencephalogram (EEG) power. Both types of sleep spindles appeared after slow wave activities of background EEG decreased. Moreover, the appearance of sleep spindles provided increasing EEG slow wave activities in the subsequent period. Further, the present results showed that an appearance of 14 Hz sleep spindle facilitated slow wave activities at the centro‐parietal areas, while an appearance of 12 Hz sleep spindle facilitated slow wave activities at the fronto‐central areas. These results suggest that sleep spindles provide cortical de‐arousal, and serve to maintain sleep.
Design Techniques and Modeling for 60GHz Applications With a 65nm-CMOS-RF Technology

To exploit the unlicensed band at frequencies around 60 GHz, a certain number of design rules is considered. This paper highlights the difficulties to design a millimeter CMOS power amplifier (PA). A model of a compact inductor and interconnect lines is detailed. This model takes into account substrate and resistive parasitic. A 65 nm CMOS technology from STMicroelectronics has been used. Innovative techniques are implemented in the design of a power amplifier (PA) which is optimized to deliver the maximum linear output power. To obtain good performances in a small surface of silicon, it has been designed, with both lumped and distributed elements. The PA delivers a linear output power of 8.9 dBm with just an area of 0.48 mm*0.6 mm including pads.
High seroprevalence of Helicobacter pylori infection in patients with systemic sclerosis: association with esophageal involvement.

OBJECTIVE To determine the prevalence and clinical relevance of Helicobacter pylori infection in patients with systemic sclerosis (SSc). METHODS Serum samples were obtained from 124 patients with SSc (67 with limited cutaneous SSc, 57 with diffuse cutaneous SSc). Fifty samples from age and sex matched individuals were used as controls. IgG antibodies to H. pylori infection were measured by ELISA. RESULTS IgG antibodies to H. pylori were found in 55.6% (69 of 124) of the patients with SSc, significantly more than in the controls. There was a significant correlation of the presence of antibodies to H. pylori with the prevalence of esophageal hypomotility in the patients with SSc (p < 0.02). CONCLUSION Patients with SSc have H. pylori infection at a higher prevalence than the general population. H. pylori might play a role in the development of esophageal dysfunction in SSc.
Osmosensing and signaling in the regulation of mammalian cell function

Volume changes of mammalian cells as induced by either anisoosmolarity or under isoosmotic conditions by hormones, substrates and oxidative stress critically contribute to the regulation of metabolism, gene expression and the susceptibility to stress. Osmosensing (i.e. the registration of cell volume) triggers signal transduction pathways towards effector sites (osmosignaling), which link alterations of cell volume to a functional outcome. This minireview summarizes recent progress in the understanding of how osmosensing and osmosignaling integrate into the overall context of growth factor signaling and the execution of apoptotic programs.
System Design Issues in a HQPM-Based Transmitter

This paper presents the analysis of signal quality and the efficiency performance in an RF transmitter using hybrid quadrature polar modulation (HQPM) scheme. The measurement results of the Class-ii power amplifier and Class-5 modulator are applied in this analysis. The path-delay difference between the envelope and the phase signal is also considered. Output spectra with and without predistortion are both shown to demonstrate improvement from the predistortion function. The simulated and experimental results have validated the key feature of the HQPM architecture, that its adjacent channel power ratio and DC-to-RF efficiency are not sensitive to the output power level.
Should protein intake be restricted in predialysis patients?

There are also no data supporting the second assumpIn the last decade, two findings have cast doubt on tion, with the obvious exception of starting dialysis in the wisdom of administering low-protein diets to CRF severely uremic patients. The third assumption is also patients: First, a large body of evidence has documented unsupported by the literature: Protein nutrition of CRF that hypoalbuminemia in dialysis patients is a major risk patients is usually maintained or improved by low-profactor for mortality, whether present at the onset of tein or supplemented very low protein diets. Hence, a dialysis or developed during dialysis [4‐19]. Other indi- well-planned, low-protein diet not only maintains or imces of nutritional status, such as urea nitrogen appear- proves nutritional state (including serum albumin levels) ance and predialysis levels of creatinine and cholesterol, in predialysis patients, but by reducing symptoms, it also are also correlated with mortality [4‐19]. Second, the delays the need for dialysis. Moreover, substantial evihypothesis that protein restriction slows the progression dence suggests that it may also slow the rate of progresof CRF (another rationale for its use) has not been un- sion of renal insufficiency. equivocally confirmed (discussed later here). As a result The benefits of a nutritional regimen include the folof these findings, some workers have questioned the lowing: (a) reduction in (or delayed onset of) symptoms wisdom of restricting protein intake [20‐22]. Further- and signs of uremia; (b) forestalling complications by more, they have suggested that if spontaneous protein lowering the accumulation of waste products at any given intake falls below 0.8 g/kg/day, patients are at increased level of glomerular filtration rate (GFR); and (c) perhaps risk of malnutrition, and the appropriate response is to slowing the rate of decline of GFR. Objections that have start dialysis unless protein intake can be increased. The been raised include cost, poor compliance, and perhaps assumptions underlying these recommendations are that: the increased risk of malnutrition. In this article, we (a) protein nutrition will improve in predialysis patients review the evidence supporting each of these benefits, if protein intake increases; (b) dialysis improves dietary as well as the evidence for each of these objections. intake and nutritional status; and (c) low protein intake causes malnutrition in predialysis patients.
CLINICIAN ’ S CORNER CARE OF THE AGING PATIENT : FROM EVIDENCE TO ACTION Nonpharmacologic Management of Behavioral Symptoms in Dementia

Mr P is a 93-year-old bachelor who has lived in the United States since emigrating from Mexico at age 8. He began to have memory problems 13 years ago such as forgetting why he walked into a room or whether he had taken his medications. Mr P sought treatment in 2004 and scored 29 of 30 points on the Mini-Mental State Examination (MMSE; normal cognition score 24). His memory impairment, coupled with results from brain computed tomography showing white matter changes and bilateral and frontotemporal atrophy, led to diagnosis of mild cognitive impairment due to brain vascular disease. By 2010, Mr P’s score had declined by 8 points (MMSE, 21/30) and his course of illness was considered consistent with mild progressive dementia. Mr P lives with Mr C, a cousin who is also his primary caregiver. Mr P has no children and all other family lives in Mexico. His caregiver is employed full time, which requires that Mr P stay at home alone. Mr P relies on his caregiver to organize and administer his 13 medications and to perform instrumental activities such as shopping and cooking. He dresses and bathes independently. Mr P maintained a positive mood as his disease progressed. He lacked insight into his memory problems. Neuropsychological testing revealed major impairments in executive function, verbal and spatial memory, wordfinding ability, and recall. His other diagnoses included hypertension, type 2 diabetes mellitus, lower extremity peripheral neuropathy, and coronary artery disease. Mr P’s dementia progressed, he napped excessively during the day, experienced nighttime restlessness, and frequently awakened Mr C. Additionally, he withdrew from gardening and other previously enjoyed activities and reported feelings of insecurity and loneliness.
A Compact Superconducting Solenoid for China-ADS Injector II

A compact solenoid for the China Accelerator Driven Subcritical System (China-ADS) injector II has been developed. It includes a focusing solenoid and two steering dipoles. The magnet is compact with an entire length of 160 mm, including the helium vessel and the side flanges. Nonlinear optimization method was used to meet the requirement of focusing strength and stray field with minimized solenoid volume. The steering dipoles are placed inside the solenoid to reduce the magnet size. The structural analysis, quench protection design, and fabrication and test results are presented in this paper.
An analysis on the applicability of supervised learning algorithms on card games

Data mining is the process of extracting patterns from large data sets by combining methods from statistics and artificial intelligence with database management. One of the classes of data mining is classification, where the goal is to generalize a known structure to apply to new data. Supervised learning, a branch of the classification algorithms uses a set of training data to produce an inferred function, called a classifier, which is then used to predict the correct output value for any valid input object. This approach allows supervised learning algorithms to be applied with notable success on games, by predicting the outcome of future matches based on the stored results of previously played matches. We will present the outcome of applying two supervised learning algorithms on a very popular card game, called “Dominion”.
Sedo-analgesia in neurologically ill patients: guidelines revisited.

To the Editor: We read with great interest the recent guidelines for the management of spontaneous intracerebral hemorrhage in adults developed by Broderick et al.1 First of all we want to congratulate the authors for their excellent review about the appropriate management of these neurologically ill patients, but we would like to make some comments. When we read the section concerning the sedatives and analgesics drugs, we remained worried due to the recommendation of etomidate as a useful sedative for these patients. We absolutely agree with the importance of an adequate sedo-analgesic regimen. However, we must remember that a …
Single and bilayer films of silver and gold for active plasmonics: Structural properties, dielectric permittivities and radiation resistance

In this work, we present experimental study on structural peculiarities and optical properties of single silver, gold and bilayer films of these metals. We illustrate that the treatment of substrate defines structural quality and roughness of the fabricated films. Considering the problem of radiation (temperature) resistances of plasmonic/active material systems, films covered by a layer of PMMA and a monolayer of quantum dots were under study in the presence of cw laser radiation. We demonstrate an irreversible effect of cw laser pumping radiation of a moderate power density on the properties of the studied plasmonic/active material system.
Numerical Analysis and Sensitivity Study of Non-Premixed Combustion Using LES

Non-premixed turbulent combustion Computational Fluid Dynamics (CFD) has been carried out in a simplified methanefuelled coaxial jet combustor employing Large Eddy Simulation (LES). The objective of this study is to evaluate the performance of LES in modelling non-premixed combustion using a commercial software, FLUENT, and investigate the effects of the grid density and chemistry models employed on the accuracy of the simulation results. A comparison has also been made between LES and Reynolds Averaged Navier-Stokes (RANS) predictions. For LES grid sensitivity test, 2.3 and 6.2 million cell grids are employed with the equilibrium model. The chemistry model sensitivity analysis is achieved by comparing the simulation results from the equilibrium chemistry and steady flamelet models. The predictions of the mixture fraction, axial velocity, species mass fraction and temperature by LES are in good agreement with the experimental data. The LES results are similar for the two chemistry models but influenced considerably by the grid resolution in the inner flame and near-wall regions. Keywords—Coaxial jet, reacting LES, non-premixed combustion, turbulent flow.
Automatic SAR Simulation Technique for Object Identification in Complex Urban Scenarios

Most of the existing SAR simulators provide simulated images only for visual interpretation. This paper presents a new approach for supporting the automatic interpretation of meter resolution SAR images in complex urban scenarios. To this end, an automatic system for generating and geocoding of simulated images has been developed, based on the SAR simulator RaySAR and digital surface models as geometric information for urban scenes. Various simulated images and different layers (layover, shadow, double bounce, and ground) are generated for the whole scene as well as for individual buildings, with consideration of neighborhood influences. The proposed approach is tested on an area in central Munich with a LiDAR digital surface model as the input. The simulated images are compared with a TerraSAR-X spotlight image and show good geocoding accuracy, reasonable mask layers, and precise individual building layover contours.
RegRessIon oF CoRonARy ATheRosCleRosIs In DIAbeTes : FACT oR FICTIon ?

Diabetes has threatened our country with its epidemic nature and problems, and India has the dubious distinction of being the “Diabetes Capital of the World”. Today, the medical community unhappily accepts, and the public should advisably be aware, that diabetes is a coronary heart disease risk equivalent. Diabetes leads to microvascular disease ( retinopathy, nephropathy and neuropathy), and macrovascular disease (atherosclerotic coronary, cerebral and peripheral vascular disease). And this diabetic macrovasculopathy is responsible for 80% of mortality and 75% of hospitalization in the diabetic population. (1) Consequently, the clinicians and research workers have great interest in assessing whether preventive measures and treatment strategies have any effect on the regression of coronary atherosclerosis.