Miracle-dz/UniFAR-FTUs huggingface dataset:
Bioestimulación cutánea periocular con plasma rico en plaquetas

La presente revision fue realizada con el objetivo de ampliar los conocimientos sobre el envejecimiento cutaneo y los tratamientos restitutivos empleados en la cirugia plastica ocular, especialmente la bioestimulacion cutanea con plasma rico en plaquetas, como alternativa novedosa de rejuvenecimiento periocular. Se realizo una busqueda bibliografica amplia y actualizada en bases de datos que ofrece Infomed, como Ebsco, Hinari, Pubmed, Google academico y textos basicos de Oftalmologia y Cirugia Estetica. El plasma rico en plaquetas es un preparado biologico efectivo para la bioestimulacion cutanea; incrementa la produccion de colageno; elastina y acido hialuronico, proporciona una piel con mas brillo, mejor textura, hidratacion y elasticidad; presenta multiples ventajas y minimas complicaciones, lo que contribuye a elevar la calidad de vida de los pacientes.
Flow Visualization Based on Rendering of 3D Surface Texture

Inspired by Jarke J. van Wijkpsilas rdquoImage Based Flow Visualizationrdquo (IBFV) and bump mapping techniques, this paper proposes a new algorithm for flow visualization based on rendering of 3D surface texture. Instead of using spot noise as background image, we use a set of height maps that are generated by fractal models. By changing model parameters, we can produce different rough surface textures, which can be rendered to produce 3D effect. Meanwhile, more visually attractive scenes can be obtained by changing different illumination directions. The proposed method is particularly effective for visualizing flow field with height data.
Relationele subtypes bij voorzetselobjecten

In de meeste grammaticahandboeken wordt de tweedeling binnen de nominale ob¬jec¬ten, nl. die tussen DO en IO, als oncontroversieel ervaren. In deze bijdrage vragen we ons af of deze tweedeling niet een tegenhanger zou kunnen hebben in het domein van de prepositionele objecten. Daarbij gaan we uit van een niet te restrictieve op¬vatting van voorzetsel¬¬objecten, en richten we onze aandacht op verwante predikaten in het domein van zowel de nominale als de prepositionele objecten. Wij pre¬ten¬de¬ren niet met het hierna te geven overzicht een kader te schetsen voor alle in aan¬mer¬king komende predikaten met voorzetselobject (VZO), en dus voor alle mogelijke relationele subtypes. Wel exploreren we een richting om het denken over voor¬zet¬sel¬objecten evengoed in relationele termen te laten verlopen als bij de nominale ob¬jec¬ten gebruikelijk is. Met de studie van objecten en van het onderscheid tussen no¬mi¬nale en prepositionele representanten, treden we ook enigszins in het spoor van een van de vele onderzoeksthema's die de gehuldigde in zijn veelzijdige weten¬schap¬pe¬lijke carriere heeft verkend.
PERFORMANCE ANALYSIS OF TURBO CODED OFDM OVER UNCODED & CONVOLUTIONAL CODED OFDM

Orthogonal Frequency Division Multiplexing (OFDM) is a suitable candidate for high data rate transmission with Forward Error Correction (FEC) methods over wireless channels. Turbo codes are one of the best error correcting codes. In this paper performance of Turbo coded OFDM (T-COFDM) over uncoded & convolutional coded OFDM (CCOFDM) is compared in terms of Bit Error Rate (BER) versus Eb/No.
Role of TSC‐22 during early embryogenesis in Xenopus laevis

Transforming growth factor‐β1‐stimulated clone 22 (TSC‐22) encodes a leucine zipper‐containing protein that is highly conserved. During mouse embryogenesis, TSC‐22 is expressed at the site of epithelial–mesenchymal interaction. Here, we isolated Xenopus laevis TSC‐22 (XTSC‐22) and analyzed its function in early development. XTSC‐22 mRNA was first detected in the ectoderm of late blastulae. Translational knockdown using XTSC‐22 antisense morpholino oligonucleotides (XTSC‐22‐MO) caused a severe delay in blastopore closure in gastrulating embryos. This was not due to mesoderm induction or convergent‐extension, as confirmed by whole‐mount in situ hybridization and animal cap assay. Cell lineage tracing revealed that migration of ectoderm cells toward blastopore was disrupted in XTSC‐22‐depleted embryos, and these embryos had a marked increase in the number of dividing cells. In contrast, cell division was suppressed in XTSC‐22 mRNA‐injected embryos. Co‐injection of XTSC‐22‐MO and mRNA encoding p27Xic1, which inhibits cell cycle promotion by binding cyclin/Cdk complexes, reversed aberrant cell division. This was accompanied by rescue of the delay in blastopore closure and cell migration. These results indicate that XTSC‐22 is required for cell movement during gastrulation though cell cycle regulation.
HypoxamiRs and cancer: from biology to targeted therapy.

SIGNIFICANCE Hypoxia is a hallmark of the tumor microenvironment and represents a major source of failure in cancer therapy. RECENT ADVANCES Recent work has generated extensive evidence that microRNAs (miRNAs) are significant components of the adaptive response to low oxygen in tumors. Induction of specific miRNAs, collectively termed hypoxamiRs, has become an accepted feature of the hypoxic response in normal and transformed cells. CRITICAL ISSUES Overexpression of miR-210, the prototypical hypoxamiR, is detected in most solid tumors, and it has been linked to adverse prognosis in many tumor types. Several miR-210 target genes, including iron-sulfur (Fe-S) cluster scaffold protein (ISCU) and glycerol-3-phosphate dehydrogenase 1-like (GPD1L), have been correlated with prognosis in an inverse fashion to miR-210, suggesting that their down- regulation by miR-210 occurs in vivo and contributes to tumor growth. Additional miRNAs are modulated by decreased oxygen tension in a more tissue-specific fashion, adding another level of complexity over the classic hypoxia-regulated gene network. FUTURE DIRECTIONS From a biological standpoint, hypoxamiRs are emerging modifiers of cancer cell response to the adaptive challenges of the microenvironment. From a clinical perspective, assessing the status of these miRNAs may contribute to a detailed understanding of hypoxia-induced mechanisms of resistance and/or to the fine-tuning of future hypoxia-modifying therapies.
Effect of acute static stretching on force, balance, reaction time, and movement time.

PURPOSE The purpose of the study was to investigate the effect of an acute bout of lower limb static stretching on balance, proprioception, reaction, and movement time. METHODS Sixteen subjects were tested before and after both a static stretching of the quadriceps, hamstrings, and plantar flexors or a similar duration control condition. The stretching protocol involved a 5-min cycle warm-up followed by three stretches to the point of discomfort of 45 s each with 15-s rest periods for each muscle group. Measurements included maximal voluntary isometric contraction (MVC) force of the leg extensors, static balance using a computerized wobble board, reaction and movement time of the dominant lower limb, and the ability to match 30% and 50% MVC forces with and without visual feedback. RESULTS There were no significant differences in the decrease in MVC between the stretch and control conditions or in the ability to match submaximal forces. However, there was a significant (P < 0.009) decrease in balance scores with the stretch (decreasing 9.2%) compared with the control (increasing 17.3%) condition. Similarly, decreases in reaction (5.8%) and movement (5.7%) time with the control condition differed significantly (P < 0.01) from the stretch-induced increases of 4.0% and 1.9%, respectively. CONCLUSION In conclusion, it appears that an acute bout of stretching impaired the warm-up effect achieved under control conditions with balance and reaction/movement time.
Sorting of Ion Pumps in Polarized Epithelial Cells. a

The physiologic functions of a P-type ATPase are determined not only by its catalytic and regulatory properties but also by its distribution among a cell's various membranous compartments. With polarized epithelial cells that mediate vectorial ion fluxes, the restriction of P-type ion pumps to one or the other distinct domains of the plasmalemma in large measure determines the parent tissue's solute and fluid transport capacities. The biologic significance of these anisotropic distributions is well illustrated by the mechanisms through which the Na,K-ATPase drives the majority of active epithelial secretory and absorptive processes. ] In most epithelial cells, the Na,K-ATPase is restricted to the basolateral plasmalemmal domain.2 This membrane surface rests on the epithelial basement membrane, is in contact with the extracellular fluid compartment, and is involved in extensive contacts with neighboring epithelial cells. The basolateral membrane is separated by tight junctions from the apical plasmalemma, which generally confronts a compartment that is topologically continuous with the extracorporeal space. The nonequilibrium ion distributions generated by the sodium pump are exploited by secondary active transport systems to drive uphill secretory and absorptive fluxes. By expressing different classes of transport systems and restricting their distributions to one or the other surface compartment, epithelial cells can use the basolateral population of the Na,K-ATPase to catalyze a remarkably diverse array of unidirectional transport processes. To achieve polarized distribution of P-type ATPase proteins, epithelial cells must be able to target newly synthesized ion pumps to the correct membrane surfaces and to retain them there following their delivery. To participate in these sorting functions, P-type ATPase subunit polypeptides must encode information within their structures that specify their sites of ultimate functional residence. Furthermore, machinery within the epithelial cell must be able to recognize this information and act on its messages3 Efforts to understand the nature of these sorting signals and of the cellular components that interpret them have largely relied on the extensive homology that relates the members of the P-type ATPase family. This high degree of structural
Beyond Re-Engineering: The Three Phases of Business Transformation

New Information-technology-based capabllities make It possibie to achleve systematic and dramatic gains in business performance. Reengineering offersone method to access these gains, but a broader process of business transformation explored in this paper can give enterprises a greater range of benefits. This three-phase transformation process starts with structured automation and re-engineering efforts, builds on new infrastructure and capabilltles to enhance and extend the orginal business, and then redefines it to create new businesses.
Performance of a single parity check turbo product coded multicarrier DS-CDMA system

This paper presents a multicarrier asynchronous direct-sequence code-division multiple-access (DS-CDMA) system wherein the output of a turbo product encoder modulates multiple band-limited DS-CDMA waveforms, which are transmitted in parallel at different carrier frequencies. The receiver detects and combines signals for the desired user and feeds an iterative decoder. The performance of this system is compared to that of a conventional single-carrier DS-CDMA system with a RAKE receiver, assuming a slowly varying frequency-selective Rayleigh fading channel. At roughly equivalent receiver complexity, results demonstrate similar performance in presence of additive white Gaussian noise and multiple-access interference and superior performance of the multicarrier system in the presence of partial-band interference.
Modeling emergency events to evaluate the performance of time-critical WSNs

Wireless sensor networks designed for critical tasks must be able to offer near real-time feedback about emergency events, allowing to supervise these events with a reasonable degree of accuracy within strict delay bounds. Achieving such high responsiveness in a distributed environment requires several improvements to currently available WSN protocols and technologies at different layers; such enhancements typically rely on simulation, at least in a preliminary phase. To accurately evaluate the performance of WSNs in near real-time event tracking we developed an event generation framework compatible with the ns- 2 simulator that includes tools to model intruder detection events, as well as fire and gas propagation scenarios. In this paper we describe the analytical models developed, and then we present the potential capabilities of the proposed framework, along with some visual examples of different types of events which confirm its correct behavior.
Planification de saisie pour la manipulation d'objets par un robot autonome

L'evolution autonome d'un robot dans un environnement evolutif necessite qu'il soit dote de capacites de perception, d'action et de decision suffisantes pour realiser la tâche assignee. Une tâche essentielle en robotique est la manipulation d'objets et d'outils. Elle intervient non seulement pour un robot seul mais egalement dans des situations d'interaction avec un humain ou un autre robot quand il s'agit d'echanger des objets ou de les manipuler conjointement. Cette these porte sur la planification de tâches de manipulation d'objets pour un robot autonome dans un environnement humain. Une architecture logicielle susceptible de resoudre ce type de problemes au niveau geometrique est proposee. Generalement, une tâche de manipulation commence par une operation de saisie dont la qualite conditionne fortement la reussite de la tâche et pour laquelle nous proposons un planificateur base sur les proprietes inertielles de l'objet et une decomposition en elements quasi-convexes tout en prenant en compte les contraintes imposees par le systeme mobile complet dans un environnement donne. Les resultats sont valides en simulation et sur le robot sur la base d'une extension des outils de planification developpes au LAAS-CNRS. Le modele geometrique 3D de l'objet peut etre connu a priori ou bien acquis en ligne. Des experimentations menees sur un robot manipulateur mobile equipe d'une pince a trois points de contacts, de capteurs de force et d'une paire de cameras stereoscopiques ont montre la validite de l'approche.
La Realidad Virtual como estrategia para la mejora de los tratamientos del tabaquismo

El tabaquismo es uno de los mayores problemas de salud publica en la actualidad. Los tratamientos multicomponentes, que incorporan tres fases de intervencion (preparacion, abandono y mantenimiento), son considerados como el tratamiento de eleccion para el abordaje esta adiccion. No obstante, las altas tasas de recaidas tras las intervenciones hacen que sea necesario incorporar estrategias mas eficaces dentro de este tipo de programas para prevenir la vuelta al consumo. Para muchos autores, el craving es la causa de la mayoria de las recaidas. Las tecnicas de exposicion a pistas o senales consisten en la exposicion controlada y repetida a estimulos o entornos asociados al uso de la sustancia, con el objetivo de reducir las respuestas de craving en estas situaciones. La Realidad Virtual ha mostrado su eficacia en el abordaje de diferentes trastornos como metodo de exposicion. Es este articulo, se propone el uso de tecnicas de exposicion a traves de entornos virtuales para la mejora del tratamiento del tabaquismo.
Mineração de series temporais de dados de sensores

Redes de sensores tem aumentado a quantidade e variedade de dados temporais disponiveis. Com isto, surgiram novos desafios na definicao de novas tecnicas de mineracao, capazes de descrever caracteristicas distintas em series temporais. A literatura correlata endereca problemas diversos, como indexacao, classificacao, definicao de vetores de caracteristicas e funcoes de distâncias mais eficazes. No entanto, a maioria dos trabalhos atuais tem como objetivo descrever e analisar os valores de uma serie temporal, e nao sua evolucao. Alem disto, varios fenomenos requerem uma analise mais elaborada, capaz de relacionar varias grandezas. Tal tipo de analise nao pode ser realizada pela maioria das tecnicas existentes hoje. Esta dissertacao apresenta uma tecnica que descreve series temporais sob uma premissa diferente - a de caracterizar a oscilacao das series e nao seus valores propriamente ditos. O novo descritor apresentado - TID ES (TIme series oscillation D EScriptor) - utiliza os coeficientes angulares de uma segmentacao linear da curva que representa a evolucao das . series analisadas, em multiplas escalas. Com isso, permite a comparacao e a mineracao de series utilizando varias granularidades, enriquecendo a analise efetuada. As principais contribuicoes sao: ~I) A especificacao de um descritor que caracteriza a oscilacao de series temporais, ao inves de seus valores, utilizando multiplas escalas; (II) A implementacao deste descritor, validada por meio de dados sinteticos e reais; (III) A extensao do descritor de modo a suportar a analise de coevolucao em um conjunto de series Abstract
Fast simulation of multilayered power delivery network using multilayered triangular subcell method and block-type leapfrog scheme

This paper describes a multilayered triangular subcell method (MTSM) combined with a block-type leapfrog scheme for the fast simulation of a multilayered power delivery network (PDN). An existing triangular subcell method is the method to avoid increasing in the number of meshes around small apertures without degrading the accuracy. In this work, we improve it to be able to deal with the multilayered PDN and combine it with the block-type leapfrog scheme. This combination makes sense because the equivalent circuit model obtained by MTSM has suitable structure for the block-type leapfrog scheme. We demonstrate that the proposed method is more efficient than existing solvers by showing some numerical results.
Motion Capture Fundamentals A Critical and Comparative Analysis on Real-World Applications

In this paper we provide the reader with a simple, yet thorough, overview of what is motion capture, its history and evolution so far and processes used in acquiring the tri-dimensional data of the recorded scene, take or animation. A brief look at the “mocap” process’s (short for motion capture) structure is given followed by an extensive list of the technologies behind the most popular systems used today. We dive into the inner works of acoustical, mechanical, magnetic and optical mocap systems, also discussing the differences between active, passive and markerless optical systems, since these are the most popular of the above referred. Later on we also provide some insight into facial motion capture, right after we compare the data acquisition systems and quickly overview the generic data file structure. Finally we provide examples of real-world applications and some possible research fields in the area along with our conclusions.
Impact of Coreference Resolution on Slot Filling

In this paper, we demonstrate the importance of coreference resolution for natural language processing on the example of the TAC Slot Filling shared task. We illustrate the strengths and weaknesses of automatic coreference resolution systems and provide experimental results to show that they improve performance in the slot filling end-to-end setting. Finally, we publish KBPchains, a resource containing automatically extracted coreference chains from the TAC source corpus in order to support other researchers working on this topic.
Adolescent Health Care and the Trainee: Roles of Self-Efficacy, Standardized Patients, and an Adolescent Medicine Rotation

Purpose Pediatric residents often cite a lack of confidence with adolescents owing to minimal exposure during training. Self-efficacy has been evaluated in a general context but not in relation to perception of knowledge and communication skill. Study objectives were to evaluate resident self-efficacy during a month-long adolescent rotation and to assess knowledge and communication skills in their relationship to self-efficacy. Methods Data were collected as part of the adolescent medicine rotation for pediatric residents at a local children’s hospital. Residents completed 2 standardized patient cases at the beginning of the rotation and a self-efficacy instrument before/after the cases and at the end of the rotation. The study assessed trends in self-efficacy using repeated-measures analysis of variance and &khgr;2 tests to examine relationships between self-efficacy and knowledge as well as communication in preventative and sexually transmitted infection adolescent health. Results Resident (n = 44) self-efficacy levels significantly changed over all time points and were significantly related to knowledge and communication levels. Although self-efficacy levels decreased immediately after the standardized patient cases, all self-efficacy items were significantly higher at the end of the rotation. Residents confident or very confident in general health topics were deficient in asking basic history items and residents confident or very confident in high-risk topics often did not actually assess these areas with patients. Conclusions Residents’ personal assessments on paper may differ from actual clinical interactions. Standardized patient cases expose resident strengths and weaknesses with adolescents, and a month-long adolescent rotation allows for repetitive experiences with special adolescent health care topics with associated increase in self-efficacy, knowledge application, and communication skill.
Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality

Background The long-term natural history of chronic obstructive pulmonary disease (COPD) in terms of successive severe exacerbations and mortality is unknown. Methods The authors formed an inception cohort of patients from their first ever hospitalisation for COPD during 1990–2005, using the healthcare databases from the province of Quebec, Canada. Patients were followed until death or 31 March 2007, and all COPD hospitalisations occurring during follow-up were identified. The hazard functions of successive hospitalised COPD exacerbations and all-cause mortality over time were estimated, and HRs adjusted for age, sex, calendar time and comorbidity. Results The cohort included 73 106 patients hospitalised for the first time for COPD, of whom 50 580 died during the 17-year follow-up, with 50% and 75% mortality at 3.6 and 7.7 years respectively. The median time from the first to the second hospitalised exacerbation was around 5 years and decreased to <4 months from the 9th to the 10th. The risk of the subsequent severe exacerbation was increased threefold after the second severe exacerbation and 24-fold after the 10th, relative to the first. Mortality after a severe exacerbation peaked to 40 deaths per 10 000 per day in the first week after admission, dropping gradually to 5 after 3 months. Conclusions The course of COPD involves a rapid decline in health status after the second severe exacerbation and high mortality in the weeks following every severe exacerbation. Two strategic targets for COPD management should include delaying the second severe exacerbation and improving treatment of severe exacerbations to reduce their excessive early mortality.