Miracle-dz/UniFAR-FTUs huggingface dataset:
A Multiplexed Human Papillomavirus 16 and 18 Diagnostic Chip for Cervical Cancer in Limited-Resource Settings

Abstract 16PurposeDespite being treatable, cervical cancer is responsible for 300,000 deaths annually and is the second most frequent cause of cancer-related death worldwide. The burden of cervical cancer disproportionately falls on developing countries, where 87% of deaths occur from limited or no resources for screening. Of cervical cancer cases, 99% are caused by human papillomavirus (HPV), with more than 70% of cases from HPV genotypes 16 and 18. We developed a low-cost cervical cancer diagnostic chip to detect HPV 16 and 18 DNA quickly and reliably in limited-resource settings (LRSs). MethodsUnlike conventional HPV diagnostics that use polymerase chain reaction and resource-intensive equipment, our chip used isothermal—one temperature—amplification, specifically loop-mediated amplification, and required only a heat source, which made it suitable for LRSs. Amplified DNA was visually detected on a lateral flow strip, which is similar to a pregnancy test, providing a simple yes or no readout. Specific li.
Reciclando la clasificación sinóptica de Font: reconstrucción con ERA40 y agrupamiento PCA

RESUMEN Las clasificaciones sinópticas ayudan a entender la variabilidad y complejidad de los llamados patrones meteorológicos, o situaciones, a escala sinóptica. Hay una gradación de clasificaciones, desde las subjetivas, con caracterizaciones conceptuales y diagnósticas, hasta las clasificaciones objetivas, basadas en soporte numérico y con un amplio abanico de familias de algoritmos asociados, pasando por clasificaciones intermedias que tienen carácter mixto. En este estudio se revisan la clasificación objetiva de RIBALAYGUA y BORÉN (1995) y la clasificación subjetiva de FONT (2000). Esta última propone 23 patrones sinópticos, ilustrados con situaciones de 23 fechas concretas, en general de la década de 1970-1980. Se recuperan los reanálisis ERA40 ( UPPALA et al., 2005) del European Centre for Medium-range Weather Forecasts (ECMWF) correspondientes a esas 23 fechas y se dibujan los campos básicos con las herramientas actuales y estilo de visualización de predicción operativa. Se compara así el querer de la mano con el querer de la máquina . Se aplica, además, a estas 23 situaciones un algoritmo de agrupamiento «análisis de componentes principales» (PCA por sus siglas en inglés; JOLLIFFE, 1986) similar al vigente en AEMET para el sistema de predicción por conjuntos del ECMWF , con el propósito de aprender sobre la naturaleza de la variabilidad y diversidad de estos patrones. Se trata, pues, de reciclar un conocimiento muy conceptual y valioso, el de Font, conectándolo con el potencial de las herramientas numéricas actuales para, en definitiva, ver qué podemos aprender .
Metastatic breast cancer with osteolytic skull lesions suspected to be multiple myeloma

analysis showed one positive dipstick test for protein. Chest X-ray demonstrated cardiomegaly and pulmonary edema. Multiple osteolytic lesions in the ribs, spine, pelvis, both femurs, and both humeri were detected on both chest and abdominal X-rays. Additional X-rays of the skull and lumbar spine showed punched out lesions (Fig. 1). Brain computed tomography (CT) was per-CaseReport We report a case of breast cancer with osteolytic skull lesions which mimicked osteolytic lesions in multiple myeloma. A 60-year-old female was admitted to our hospital due to confused mentality. Laboratory tests showed the findings of an increased calcium level, kidney failure, and anemia. Multiple osteolytic lesions were detected in the ribs, spine, humerus, and pelvis on X-rays. The skull showed the punched out sign. Accordingly we initially suspected multiple myeloma; however, monoclonal protein was not detected in serum and urine and the number of plasma cells was not increased in bone marrow examination. In bone marrow examination, metastatic cancer was detected and biopsy revealed breast cancer. Finally, breast cancer with multiple metastases including those to bone, liver, and lung was diagnosed. Therefore, when a patient presents with multiple osteolytic lesions, we need to consider metastasis from solid cancer in the differential diagnosis as well as multiple myeloma.
Genetic aspects of congenital heart defects

Congenital heart defects (CHDs) occur mostly sporadic, but familial CHD cases have been reported. Mutations in several genes, including NKX2.5, GATA4 and NOTCH1, were identified in families and patients with CHD, but the mechanisms underlying CHD are largely unknown. We performed genome-wide linkage analysis in a large four-generation family with autosomal dominant CHD (including atrial septal defect type I and II, tetralogy of Fallot and persistent left superior vena cava) and low atrial rhythm, a unique phenotype that has not been described before. We obtained phenotypic information including electrocardiography, echocardiography and DNA of 23 family members. Genome-wide linkage analysis on 12 affected, 5 unaffected individuals and 1 obligate carrier demonstrated significant linkage only to chromosome 9q21–33 with a multipoint maximum LOD score of 4.1 at marker D9S1690, between markers D9S167 and D9S1682. This 48-cM critical interval corresponds to 39 Mb and contains 402 genes. Sequence analysis of nine candidate genes in this region (INVS, TMOD1, TGFBR1, KLF4, IPPK, BARX1, PTCH1, MEGF9 and S1PR3) revealed no mutations, nor were genomic imbalances detected using array comparative genomic hybridization. In conclusion, we describe a large family with CHD and low atrial rhythm with a significant LOD score to chromosome 9q. The phenotype is representative of a mild form of left atrial isomerism or a developmental defect of the sinus node and surrounding tissue. Because the mechanisms underlying CHD are largely unknown, this study represents an important step towards the discovery of genes implied in cardiogenesis.
Electronic prescription anomalies: a study of frequencies, clarification and effects in Finnish community pharmacies

To investigate the frequency of e‐prescriptions containing prescription anomalies (=errors, ambiguities and other shortcomings), and the types of e‐prescription anomalies occurring in Finnish community pharmacies. Further objectives were to investigate how these anomalies were clarified, together with the time required, as well as the effects such anomalies had in the pharmacies concerned.
A Cross-Sectional Study of Chronic Impairments and Activity Limitations in Women at Least Six Months Post-Operative for Breast Cancer: An Exploratory Study.

2 Introduction . 6 LITERATURE REVIEW . 7 International Classification of Functioning, Disability, and Health (ICF) . 7 Impairments and activity limitations after breast cancer medical therapy. 10 1. Activity limitations . 10 2.1 Range of Motion . 12 2.2 Pain . 13 2.3 Strength . 14 3. Fear of Physical Activity . 15 Summary of the literature . 18 Study Objectives . 20 METHODS . 20 Design . 20 Participants . 20 Materials . 24 Evaluation Procedure . 27 Statistical Analysis . 29 Ethical Considerations . 30 RESULTS . 30 Participant Demographics . 30 Descriptives and Frequencies for Study Variables . 33 Relationship between DASH scores and the study variables . 36 DISCUSSION . 37 Major Findings of the Study . 37 Importance of the Findings . 38 Limitations of the study . 42 Future research . 44 CONCLUSION . 45 ACKNOWLEDGEMENTS . 46 -
Lay attitudes towards cardiovascular risk in the context of screening, prevention, and trial participation

Background: This study expands the understanding of lay attitudes towards, and perceptions of cardiovascular risk by exploring beliefs in the context of a large trial of screening and prevention in a 'healthy' population. Aims: To investigate public attitudes towards screening for cardiovascular risk, prevention of cardiovascular disease (in particular aspirin as a preventive medication), and participation in a preventive research trial. Methods: Participants were members of a healthy population (50-79 years) invited to attend screening for asymptomatic atherosclerosis, some of whom were subsequently invited to participate in a randomised control trial assessing the efficacy of aspirin in preventing cardiovascular events. The study sample included those who had not attended screening, those who were ineligible for the trial, those who had declined to participate in the trial, as well as trial participants. Semi-structured qualitative interviews and focus groups were conducted and transcribed verbatim. Transcripts were analysed inductively and interpretatively for emergent themes. Findings: Attitudes and beliefs varied both between and within groups of participants from different stages and situations from the screening and trial process. Prominent themes included: Screening attendance: Participants discussed their own attitudes often as distinct from those of 'known' or 'general' others. Salient explanations of barriers included fatalism, optimistic bias, denial and disinterest. The common phrase "what's not broken, you don't fix" seemed to imply a low risk perception for asymptomatic conditions. Conversely participants who were positive about screening attendance, due to the benefits of early diagnosis, implied individual responsibility, but often in hindsight. Screening experience: An 'at risk' result often mismatched expectations, and provoked varying reactions: some participants maintained prior beliefs about personal health and risk, seeking alternative explanations; others reinterpreted their pre-screening beliefs. Key influences on participants' reactions included the nurse-
The (In)Visible Road Map: The Role of Mentoring for First-Generation Black Female Doctoral Students at Predominantly White Institutions

iv CHAPTER 1: INTRODUCTION AND THEORETICAL FRAMEWORK . 1 Brief History of Black Women in Higher Education . 4 First-generation Students at Predominantly White Institutions . 6 Defining First-generation Students.8 Statement of the Problem . 10 Theoretical Framework . 13 Purpose of the Study . 17 Methodology . 19 Summary . 21 CHAPTER TWO: LITERATURE REVIEW. 22 Black Women’s Search for a Voice . 22 From Feminist to Womanist . 24 Black Women in Higher Education . 27 Institutional Diversity . 28 Black Graduate Students . 29 First-generation Students . 31 First-generation Doctoral Students . 32 Attrition and Black Graduate Students . 35 Mentoring Graduate Students . 40 Black Women Mentoring Black Women. 44 Summary . 46 CHAPTER THREE: METHODOLOGY . 47 Rationale for Qualitative Research . 47 Phenomenology and Phenomenological Research Method . 48 Sample and Criteria . 49 Data Collection . 51 Pilot Study . 52 Study Setting and Interview process . 52 Data Analysis . 53 Limitations of the Study . 54 CHAPTER FOUR: ORGANIZING, ANALYZING, AND SYNTHESIZING DATA . 55 Horizonalization . 55 Meaning of Units . 56 Meaning of Unit #1: (First-generation family perceptions) – How do your family and friends perceive you obtaining a Ph.D.? Has it put any pressure on you in any way? What effect did being a first-generation doctoral student play during this period of transition? 56 Meaning of Unit #2: (Outsider-Within) – How would you describe your experience of being Black in a White space? 58
Evaluation of Result of Minimally Invasive Plating Osteosynthesis (MIPO) Technique in the Treatment of Fracture Distal Tibia:A Prospective Follow-Up Study from Chhattisgarh, India

Background High speed motor vehicle accidents are on the rise over the past few years, a major cause of complex fractures of tibia. The main treatment aim of this type of fractures is reinstatement of the normal alignment and articular congruity. Although different surgical techniques are available, but minimally invasive plating osteosynthesis (MIPO) is most popular in minimal articular comminution and damage of soft tissue envelope. MIPO advantages are no periosteal dissections, no disruption of hematoma, stable fixation, early mobilization, less complications and relatively higher rates of union. The main objective of this study was to evaluate the functional and clinical outcomes of distal tibia fracture patients, treated by internal fixation by MIPO technique with locking compression plate (LCP).
The Improvement of Coralline-Like ZnGa2O4 by Cocatalysts for the Photocatalytic Degradation of Rhodamine B

To date, various methods have been used to synthesize ZnGa2O4 material to promote photodegradation performance. However, cocatalysts, which usually play a crucial role in the photocatalyst system, have not been studied extensively in photocatalytic degradation reactions. In this paper, ZnGa2O4 semiconducting material was synthesized by a traditional high-temperature solid-state reaction. The as-prepared powder was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and ultraviolet–visible diffused reflectance spectroscopy. The results indicate that the as-prepared sample is a highly crystallized granular sample with a bandgap of 4.44 eV and a uniform particle size distribution. Density functional theory (DFT) was utilized to calculate the electronic structure of ZnGa2O4. The valence bands and conduction bands were chiefly composed of O 2p atomic orbitals and the hybridization orbitals of Ga 4s4p and Zn4s4p, respectively. The photocatalytic performance was tested via the decomposition of rhodamine B (RhB) under the irradiation of ultraviolet light. Cu, Ag, Au, Ni, Pt, and Pd cocatalysts were loaded on the ZnGa2O4 photocatalyst by a photodeposition method. The relatively optimal cocatalyst of ZnGa2O4 in the photocatalytic degradation reaction is Au. Thereafter, the effect of loading different usage amounts of the Au cocatalyst for the photodegradation of the ZnGa2O4 photocatalyst was studied in detail. The experimental results displayed that the optimum photodegradation activity was confirmed with the 3 wt% Au/ZnGa2O4 sample, which was 14.1 times more than the unloaded photocatalyst. The maximum photocatalytic degradation ratio of RhB was 96.7%, with 180 min under ultraviolet light.
Effet des extraits des différents noyaux des dattes "Phoenix dactylifera L" sur les hormones sous l’effet de xylène chez les rattes Wistar albinos

The aim of this work is to study the toxic effect of xylene and to validate the protective effect of aqueous extract of the dates nuclei at the level of the thyroid gland and the liver in female Wistar Albino rats. conducted in the laboratory on 30 rats which were divided into five groups: the 1st group considered as a control, the 2nd receiving daily 1.2 ml / kg / day of xylene for 25 days, and the three remaining groups receiving daily 1200 ml / kg / J xylene and treated with 300mg / kg / day of kernel extract dates Ghars for the 3rd group, and extract of the dates kernels Mch Deglet for the 4th group, and for the last group treated with extract Deglet Nour dates kernels for 25 days. The results obtained in the present study, show that the xylene treatment induces a xylene overload, decrease in the hormones t4 and T3 with increase TSH and hyperglycemia, increase of urea, creatinine, biliribine, also an increase in the activity transaminases (TGO, TGP), alkaline phosphatase which shows that xylene induces a disruption of liver and kidney function. Our results also reveal a decrease in GSH levels, CAT activity, GST, with an increase in the level of MDA in the liver that indicates a disruption of the hepatic oxidative stress parameters. In addition, the results obtained from the histological study, show the presence of inflammation in the liver, and the presence of hepatic necrosis induced by oxidative stress. However, oral administration of dates kernel extract to different cultivars has caused a decrease in the toxic effect of xylene by maintaining the decrease of xylene in the body.
Expert strategic management systems in precision farming

Evaluating the modern market of the Internet of things, one should consider equipment connected into a single network, solutions, applications along the entire chain of product creation, including the end user. In this paper, such a binding is based on cloud information technologies. Through these technologies, the intellectualization of agrotechnology management is implemented through the creation of expert management decision support systems (DSS). The aim of the work is to consider the methodology for constructing DSS of strategic management in precision farming systems, where this type of management has not been implemented to date. To this kind of management, the task of forming strategies for the application of mineral fertilizers and ameliorants of prolonged action for all the years of various types of crop rotations is included. To solve the problem, an algorithm for the formation of optimal strategies for the application of mineral fertilizers and ameliorants, which is implemented in an analytical automated control system of agricultural technologies, through which a knowledge base (KB) is transmitted from the cloud system to local DSS, is substantiated. To select the best option from the knowledge base, the pattern recognition method is used. The technique was tested on arbitrary initial conditions of local systems, including extreme combinations of initial conditions. Based on the analysis of the loss of optimality associated with the discrepancy of the initial conditions on the local DSS and the KB, a method for controlling the formation of the BR, aimed at reducing these losses, is substantiated.
Role of Arm Mechanics During Sprint Running: A Review of the Literature and Practical Applications

ABSTRACT THE IMPORTANCE OF ARM ACTION DURING SPRINT RUNNING HAS BEEN AN ONGOING DISCUSSION AMONG PRACTITIONERS. ALTHOUGH SOME COACHES BELIEVE THAT THE ARMS SERVE TO MERELY PROVIDE BALANCE TO THE ROTARY MOMENTUM OF THE LEGS, OTHERS BELIEVE THAT THE ARMS ARE VITAL TO SPRINT RUNNING PERFORMANCE AND CONTRIBUTE TO PROPULSIVE FORCES. ALTHOUGH A LARGE BODY OF RESEARCH HAS BEEN UNDERTAKEN INTO THE EFFECTS OF LEG KINEMATICS AND KINETICS ON SPRINT RUNNING PERFORMANCE, THE ROLE OF ARM ACTION REMAINS AMBIGUOUS AND UNDERINVESTIGATED. THEREFORE, THE PURPOSE OF THIS REVIEW IS TO IMPROVE UNDERSTANDING RELATED TO ARM MECHANICS DURING SPRINT RUNNING AND PROVIDE PRACTICAL CONTEXT GUIDELINES.
Determination of sources of fine particles in different ambient atmospheres in South Korea using a chemical mass balance model

Abstract To determine the sources of particulate matter less than 2.5 μm (PM2.5 in different ambient atmospheres (urban, roadside, industrial, and rural sites), the chemical components of PM2.5 such as ions (Cl-, NO3-, SO42-, NH4+, Na+, K+, Ca2+, and Mg2+), carbonaceous species, and elements (Al, As, Ba, Cd, Cu, Fe, Mn, Ni, Pb, Se, V, and Zn) were measured. The average mass concentrations of PM2.5 at the urban, roadside, industrial, and rural sites were 31.5 ± 14.8, 31.6 ± 22.3, 31.4 ± 16.0, and 25.8 ± 12.4 μg/m3, respectively. Except for secondary ammonium sulfate and ammonium nitrate, the model results showed that the traffic source (i.e., the sum of gasoline and diesel vehicle sources) was the most dominant source of PM2.5 (17.1%) followed by biomass burning (13.8%) at the urban site. The major primary sources of PM2.5 were consistent with the site characteristics (diesel vehicle source at the roadside site, coal-fired plants at the industrial site, and biomass burning at the rural site). Seasonal data from the urban site suggested that ammonium sulfate and ammonium nitrate were the most dominant sources of PM2.5 during all seasons. Further, the contribution of road dust source to PM2.5 increased during spring and fall seasons. We conclude that the determination of the major PM2.5 sources is useful for establishing efficient control strategies for PM2.5 in different regions and seasons.
Frequency-Dependent Schroeder Allpass Filters

Since the introduction of feedforward–feedback comb allpass filters by Schroeder and Logan, its popularity has not diminished due to its computational efficiency and versatile applicability in artificial reverberation, decorrelation, and dispersive system design. In this work, we present an extension to the Schroeder allpass filter by introducing frequency-dependent feedforward and feedback gains while maintaining the allpass characteristic. By this, we directly improve upon the design of Dahl and Jot which exhibits a frequency-dependent absorption but does not preserve the allpass property. At the same time, we also improve upon Gerzon’s allpass filter as our design is both less restrictive and computationally more efficient. We provide a complete derivation of the filter structure and its properties. Furthermore, we illustrate the usefulness of the structure by designing an allpass decorrelation filter with frequency-dependent decay characteristics.
Pancreatic cancer markers based on aberrant glycosylation of serum proteins

Cancer is one of the leading causes of death worldwide. Pancreatic ductal adenocarcinoma (PDAC) is characterized by high intrinsic aggressiveness and late diagnosis, causing poor prognosis and resulting in the lowest five-year survival rate among all cancers. Nowadays, there is no biomarker for PDAC diagnosis approved. The survival rate of cancer patients increases when they are diagnosed in the early stages of the pathology; and for this reason, the research of new biomarkers is of great interest. Tumour cells present aberrant glycosylation on their cell surface and also in the secreted glycoconjugates. Hence, a strategy for new tumour biomarker discovery is based on the identification of specific glycoforms. This work has explored the glycosylation of two serum glycoproteins, the alpha-1-acid glycoprotein (AGP) and the ceruloplasmin (CP). The glycosylation of the epithelial mucins MUC1 and MUC5AC in healthy and PDAC tissues has also been analysed. El cancer es una de les principals causes de mort. L’adenocarcinoma ductal pancreatic (PDAC) es caracteritza per una alta agressivitat i un diagnostic tarda, causant un pronostic desolador i resultant en el cancer amb la taxa relativa de supervivencia als cinc anys menor. Actualment no es disposa d’un biomarcador per al diagnostic del PDAC.La supervivencia dels pacients augmenta quan son diagnosticats en els estadis inicials; per aquest motiu, la recerca de nous marcadors es de gran importancia. Les cel·lules tumorals presenten una glicosilacio aberrant en la seva superficie cel·lular i tambe en els glicoconjugats que secreten. Per tant, una estrategia per al descobriment de nous biomarcadors es basa en la identificacio de glicoformes especifiques. Aquesta tesi ha explorat la glicosilacio de dues glicoproteines del serum, la alfa-1-glicoproteina acida i la ceruloplasmina. Tambe s’ha analitzat la glicosilacio de les mucines epitelials MUC1 i MUA5AC en teixits sans i de PDAC.
A Tunable Concurrent Dual-Band Phase Shifter MMIC for Beam Steering Applications

This brief presents a dual-band tunable concurrent passive phase shifter monolithic microwave integrated circuit utilizing a two-stage dual-branch phase tuning network topology. The designed phase shifter with two independent phase tuning bands operates at 5.9 GHz and 16 GHz. The dual-band phase shifter is fabricated in a $0.25~\mu \text{m}$ GaAs process and occupies a small chip area of 0.98 mm2 (including pads). Measurement results show that transmission phases in the two frequency bands can be tuned concurrently. Phase tuning range is greater than 105° in either band. Insertion losses of less than 2.8 dB and 3.5 dB are exhibited in 5.8~6 GHz and 15.8~16.2 GHz, respectively. And amplitude imbalances within the whole phase tuning range in 5.8~6 GHz and 15.8~16.2 GHz are less than 1.1 dB and 1.3 dB, respectively. The return losses are greater than 10 dB in both frequency bands. The phase shifter is employed in a four-element dual-band phased array network. The phased array is able to independently tilt its main beam toward −20° ~ +20° in either band.