Miracle-dz/UniFAR-FTUs huggingface dataset:
Information role of analysts' target prices: Event and intra-day analysis

I have documented that target prices subsumed in downgrade recommendations are the most informative while target prices in coverage reiteration are the least informative. The First Call database enables me to extend the analysis to an intraday frequency. Conducting event studies using high frequency data, is even more critical given the advent of information technology systems has dramatically changed the landscape of stock trading. The modified approach to event study is relevant to the fast-changing trading environment in today’s capital market. For upgrades, there are significant positive market-adjusted returns lasting 20 minutes; for downgrades, there are significant negative market-adjusted returns lasting 25 to 35 minutes. By constructing portfolios on the basis of target price information measures (TP/P, ΔTP/TP-1 and ΔTP/P), I also document that the information subsumed in target price revision is more useful than target price alone. Furthermore, the dramatic rise in trading activity coupled with a shift in order imbalances implies that the market interprets recommendations with target price changes broadly as a liquidity event. More importantly, I find that target prices are informative both unconditionally and conditionally on the type of recommendations and rating revision at intraday frequency. The investors seek out more information from target price revisions when recommendations are unfavourable.
Differential response of grazing and bacterial heterotrophic production to experimental warming in Antarctic waters

Narrow annual ranges of temperature characterize polar waters. Consequently, small increases in temperature could significantly affect the metabolic processes of marine microorgan- isms. We investigated the response of bacterial heterotrophic production (BHP) and grazing rates to small temperature changes in 3 zones near the western Antarctic Peninsula — Bransfield and Ger- lache Straits, and Bellingshausen Sea — during December 2002. We performed 8 grazing experi- ments with water samples collected from depths where chlorophyll a (chl a) concentration was max- imum, and incubated the samples at ambient temperature and at -1, 1, 2 and 5°C. We expected that grazing would increase in parallel with BHP at increasing temperatures; however, temperature dif- ferentially affected these 2 microbial activities. Thus, grazing rates increased maximally at tempera- tures ≤2°C, except in 1 station in the Gerlache Strait, while BHP increased maximally at temperatures ≥2°C, except in 1 station in the Bellingshausen Sea. The percentage of grazed bacteria to BHP at the highest experimental temperatures was low (56 ± 19%) in the Gerlache Strait, high (395 ± 137%) in the Bransfield Strait and approximately balanced (97 ± 24%) in the Bellingshausen Sea. This sug- gests that differential microbial processes in each zone at increasing temperatures will also depend on the autochthonous community. The present study contributes to the understanding of the variabil- ity of polar biogeochemical fluxes, and may aid in predicting the response of microorganisms in future scenarios with local and seasonal changes in temperature.
The Fixateur Interne in the Reduction and Stabilization of Thoracolumbar Spine Fractures in Patients with Neurologic Deficit

A prospective analysis of 80 consecutive patients who underwent stabilization with the fixateur interne for thoracolumbar spine fractures with complete or incomplete paraplegia was undertaken to determine the results after bone healing. Follow-up examination at an average of 35 months (minimum, 24 months) included all 76 patients still alive. One patient died from a pulmonary embolism, and there were three other unrelated deaths. The mean wedge angle of the fractured vertebra was corrected from 17.4° to 7.9° and remained almost unchanged after 1 year (8.4°) and 2 years, or 1 year after implant removal (8.2°). Also, the wedge index showed nearly no bony loss of correction within the reduced fracture vertebra (0.61 before operation, 0.83 after operation; 0.81 at 1-year follow-up, 0.81 at 2-year follow-up, respectively). In the kyphosis angle measured by the Cobb method, however, there was a loss of 5° after implant removal within the next year because of the disc space collapsed above the fractured vertebra. In this series, 70% of the cases had no formal fusion. All 29 cases of translational displacement of 4–36 mm were anatomically reduced. No neurologic or vascular complication occurred. Posterolateral fusion or transpedicular interbody fusion in the disrupted disc space is recommended.
Switching adaptive control of mobile robots

A novel tracking and positioning adaptive control for mobile robots is designed using Lyapunov theory. Then, a switching control that changes the parameter updating law is used to improve the adaptive control in the sense of reducing high accelerations of the robot and avoiding the parameter drifting. Experimental results show a good performance of the adaptive control and its improvement with the switching control.
Electrophoretic karyotyping of the yeast genus Torulaspora

Karyotypes of yeast strains in the genus Torulaspora were determined by pulse‐field gel electrophoresis and compared with those of the related genus Zygosaccharomyces. The DNA bands ranged from 800 to 1600 kb in T. delbrueckii and 800 to 2000 kb in both T. globosa and T. pretoriensis and those numbers were about six in the three species. The chromosomes of Torulaspora strains comprised relatively smaller size of DNAs than Zygosaccharomyces strains.
High-speed InGaP/GaAs HBTs using a simple collector undercut technique to reduce base-collector capacitance

High-speed InGaP/GaAs HBTs were fabricated using a simple collector undercut (CU) technique to physically remove the collector material underneath the extrinsic base region by selective etching for reducing base-collector capacitance (C/sub BC/). The best HBTs achieved a f/sub T/ of 80 GHz and a f/sub max/ (MSG/MAG) of 171 GHz. To our knowledge, this is the highest f/sub max/ (MSG/MAG) ever reported for the InGaP/GaAs HBTs. Compared to the HBTs without CUs, the CU HBTs showed a factor of 1.38 times improvement in the highest achievable f/sub max/ (MSG/MAG) due to the significant reduction of the C/sub BC/.
A linear programming based iterative heuristic for the recreational vehicle scheduling problem

In the recreational vehicle rental business, the problem of preparing a schedule for each vehicle in the fleet (by assigning accepted bookings to available vehicles over the planning horizon) is known as the recreational vehicle scheduling problem (RVSP). The problem belongs to the class of minimum cost multicommodity network flow problems which is known to be NP-hard. A formulation of the RVSP from literature is modified to reduce the size of the problem instance. We propose an iterative construction heuristic combined with an improvement heuristic based on the solution of the LP relaxation of the problem. The heuristic exploits the integrality property of the formulation and reduces infeasibility successively at each iteration. The approach is compared with a subgradient optimisation and with CPLEX using a real-life dataset. The heuristic outperforms the subgradient optimisation for most of the datasets while it produces results within 5% of optimality when compared with CPLEX.
Successful Sport Sponsorship: Lessons from Association Football - The Role of Research

Basic research can make the difference between a successful sponsorship association and a significant marketing failure. In this paper, the importance of using benchmarking is discussed in order to help determine the likely success or failure of any particular sponsorship. It is suggested that between one and two per cent of the total sponsorship budget should be spent on research. The value of such research is demonstrated by a case study of Green Flag's sponsorship of the England national soccer team.
The Neuropsychiatric Inventory

We developed a new instrument, the Neuropsychiatric Inventory (NPI), to assess 10 behavioral disturbances occurring in dementia patients: delusions, hallucinations, dysphoria, anxiety, agitation/aggression, euphoria, disinhibition, irritability/lability, apathy, and aberrant motor activity. The NPI uses a screening strategy to minimize administration time, examining and scoring only those behavioral domains with positive responses to screening questions. Both the frequency and the severity of each behavior are determined. Information for the NPI is obtained from a caregiver familiar with the patient's behavior. Studies reported here demonstrate the content and concurrent validity as well as between-rater, test-retest, and internal consistency reliability; the instrument is both valid and reliable. The NPI has the advantages of evaluating a wider range of psychopathology than existing instruments, soliciting information that may distinguish among different etiologies of dementia, differentiating between severity and frequency of behavioral changes, and minimizing administration time.
Integrated Services Packet Network Using Bus Matrix Switch

For several years, Fujitsu has been researching and developing high-speed packet switching networks, the result being an integrated multimedia information networks architecture. This architecture has already been applied to LAN systems and can now be applied to wide area corporate networks thanks to the new developments described in this paper. The most important technology-the bus matrix switch-provides a quantum leap in processing capacity up to several Gbit/s (few millions of packets every second), while keeping a very low switching delay. The performance evaluation based on our prototype models is also considered in detail. For example, a voice delay of less than 20 ms is obtained for five-hop communication. The new technologies will greatly improve for computer networks and will also enable basic and broadband ISDN.
Breast Cancer: Influence of Taxanes on Response Assessment with Dynamic Contrast-enhanced MR Imaging.

PURPOSE To prospectively investigate the influence of taxane-containing neoadjuvant chemotherapy (T-NACT) versus non-taxane-containing NACT (NT-NACT) on the contrast material enhancement of breast cancers, benign enhancing lesions (BELs), and background parenchymal enhancement (BPE) at dynamic contrast-enhanced magnetic resonance (MR) imaging. MATERIALS AND METHODS This institutional review board-approved study was performed in 62 patients with invasive breast cancer who underwent multiagent NACT with (n = 49) or without (n = 13) taxanes between 2008 and 2011. Written informed consent was obtained. Patients underwent dynamic contrast-enhanced MR imaging according to a standardized protocol before and 2 weeks after completing NACT. The percentage reduction of enhancement of breast cancers, BELs, and BPEs was calculated for patients undergoing NT-NACT versus those undergoing T-NACT. Final surgical pathologic results served as standard of reference. Changes in mean enhancement of breast cancers, BELs, and BPEs between the regimens were compared by using the Student t test for unpaired samples; for intraindividual comparison, the Student t test for paired samples was used. RESULTS Similar rates of complete pathologic response were observed after T-NACT and NT-NACT (28 [57.2%] of 49 vs eight [61.5%] of 13). T-NACT was associated with an almost complete suppression of enhancement in not only breast cancers but also BELs and BPE in the same patients, with an average reduction of enhancement of -89.9% ± 9.3, -90.2% ± 11.8, and -91.2% ± 7.5, respectively. After T-NACT, cancers with partial (n = 21) or complete (n = 28) pathologic response exhibited a similar reduction of enhancement (-81.8% ± 17.5 vs -93.9% ± 2.3; P = .22). The reduction of enhancement of cancers after NT-NACT was significantly less pronounced than that after T-NACT (-41.1% ± 22.8 vs 88.1% ± 13.9; P < .0001), and effects on enhancement of BELs and BPE were significantly less pronounced compared with effects on enhancement of cancers in the same women (P < .0001). MR imaging led to an overestimation of response (yielded false-negative results for residual disease) in 66.7% (14 of 21) of patients after T-NACT, versus in 20% (one of five) of patients after NT-NACT. CONCLUSION The reduction of enhancement observed in breast cancers after T-NACT is, in part, unrelated to their oncologic response. MR imaging-detectable effects of taxanes represent a combination of specific antimitotic and nonspecific antiangiogenic effects. This impacts the accuracy with which dynamic contrast-enhanced MR imaging helps predict complete pathologic response to T-NACT. (©) RSNA, 2015 Online supplemental material is available for this article.
Role of organizational justice, organizational commitment and job satisfaction on quality of work life: case study of Pour-Sina state hospital personnel in Rasht

Background & Aim: Improving the quality of work life in hospital personnel is introduced as one of the important factors for ensuring the sustainability of the health system. The aim of this study was to investigate the relationship among organizational justice and commitment, and job satisfaction with quality of work life in Pour-Sina state hospital personnel. Materials & Methods: The study design was descriptive and cross-sectional, and statistical population included all of physicians, nurses, radiology and administrative staff and service workers of Poursina State Hospital in Rasht. 216 individuals were selected by quota sampling and filled the questionnaires on demographic information, quality of work life, organizational justice and commitment and job Descriptive Index(JDI). All data were analyzed with SPSS 16 software and by correlation coefficient and multiple regression. Results: Among the demographic characteristics, only work history had a significant negative correlation with quality of work life (r=-0.155,P<0.05). All dimensions of organizational commitment (except continues commitment) and organizational justice had a positive and significant relationship with quality of work life(P<0.0001). in regression analysis variables of distributive justice (P=0.0001, =0.318),pay satisfaction (P=0001.0, =0.288), affective commitment (P=0.007, =0.144), promotion satisfaction (P=0.003, =0.172), procedural justice (P=0.013, =0.139 ), and normative commitment (P=0.003, =0.172) significantly predicted the levels of quality of work life and totally explained 60% of shared variance(P<0.0001,F=46.913). Conclusion: individuals working in hospital are always at risk of burnout. Thus, it is proposed that much attention be paid to dimensions of job satisfaction, organizational commitment and justice in order to increase the quality of work life in hospital environments.
Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV‐1‐infected patients

Background:The use of protease inhibitors in the treatment of HIV-1 infection is associated with the new onset of diabetes mellitus, hyperlipidaemia and lipodystrophy. It is unclear whether these findings are coincidental or whether they reflect a causative effect of protease inhibitors. Objective:To evaluate the effect of treatment with protease inhibitors on insulin sensitivity, oral glucose tolerance and serum lipids in HIV-infected patients in order to determine whether treatment with protease inhibitors can cause peripheral insulin resistance. Design:Cross-sectional controlled study in HIV-infected patients treated with protease inhibitors to assess insulin sensitivity, oral glucose tolerance and changes in serum lipids. Methods:Sixty-seven patients treated with protease inhibitors, 13 therapy-naive patients and 18 HIV-negative control subjects were tested for insulin sensitivity (intravenous insulin tolerance test). In a subgroup of 24 treated patients, oral glucose tolerance was determined. Serum lipids prior to and under treatment with protease inhibitors were compared. Results:Patients on protease inhibitors had a significantly decreased insulin sensitivity when compared with therapy-naive patients (median, 75 and 156 μmol/l/min, respectively; p <0.001). All treated patients with impaired (n = 4) or diabetic (n = 9) oral glucose tolerance, and four out of 11 patients with normal glucose tolerance showed peripheral insulin resistance; all therapy-naive patients had normal insulin sensitivity. Treatment with protease inhibitors led to a significant increase in total triglycerides and cholesterol in the 67 treated patients (median increase, 113 and 37 mg/ml, respectively). Conclusion:Treatment with protease inhibitors is associated with peripheral insulin resistance, leading to impaired or diabetic oral glucose tolerance in some of the patients, and with hyperlipidaemia. Overall, there is a large variation in the severity and clinical presentation of protease inhibitor-associated metabolic side-effects.
Disabled: one more label.

Labels are arbitrary and subjective and are used by “in” groups to create and define deviance, to speak about the “others. ” The Social Security Administration and the Americans With Disabilities Act (ADA) invited me to join the largest minority in the United States and label myself. Should I use the word “disabled” to describe my mood swings and melancholy? I have thought a lot about whether I want the tag “disabled. ” I’ve decided that by using it I have a lot to gain. In 1987, members of my mood network were describing how long it took to get disability benefits, how difficult dealing with the Social Sccurity paperwork was, how humiliating the rejections were. To learn the bureaucratic rules, I wanted to go through the process myselfand write a how-to manual. I was interviewed by a psychiatrist for 30 minutes and signed releases for my records. As I left his office, I wondered how crazy I seemed to the physician and what he thought of me.
The Influence of Presumed Media Influence on Women’s Desire to Be Thin

This study investigated the effect of magazine use on the desire to be thin within the theoretical framework of presumed influence. Structural equation modeling supported the hypothesis that reading beauty and fashion magazines increased the drive for thinness both directly and indirectly. The indirect pathway included the perceived prevalence of the thin ideal in mass media, the presumed influence of the thin ideal on others, and the perceived influence of the thin ideal on self. Social pressure to be thin may be based both on reality and the presumption of influence on others. Results suggest potential strategies for intervention.
Mutational analysis of genes determining antagonism of Alcaligenes sp. strain MFA1 against the phytopathogenic fungus Fusarium oxysporum.

Alcaligenes sp. strain MFA1 inhibits microconidial germination and germination-tube elongation of Fusarium oxysporum f.sp. dianthi and reduces the severity of fusarium wilt of carnation, presumably as a result of its production of a siderophore (G.Y. Yuen and M.N. Schroth. 1986. Phytopathology, 76:171-176). Derivative strains of MFA1, deficient in antagonism against F. oxysporum and in iron-limited growth, were obtained by Tn5 mutagenesis. The presence of a single Tn5 insertion in the genomic DNA of each derivative strain was detected by Southern analysis. Marker-exchange mutagenesis of strain MFA1 with DNA fragments, containing Tn5 and flanking sequences cloned from representative mutants, confirmed the association of single Tn5 insertions with the loss of antifungal activity and iron-independent growth of MFA1. These results are consistent with the involvement of siderophore biosynthesis by MFA1 in the inhibition of F. oxysporum.
Tyrosine phosphorylation of LRP 6 by Src and Fer inhibits Wnt / β-catenin signaling

Low-density lipoprotein receptor-related proteins 5 and 6 (LRP5/6) function as transmembrane receptors to transduce Wnt signals. A key mechanism for signalling is Wnt-induced serine/threonine phosphorylation at conserved PPPSPxS motifs in the LRP6 cytoplasmic domain, which promotes pathway activation. Conserved tyrosine residues are positioned close to all PPPSPxS motifs, which suggests they have a functional significance. Using a cell culturebased cDNA expression screen, we identified the non-receptor tyrosine kinases Src and Fer as novel LRP6 modifiers. Both Src and Fer associate with LRP6 and phosphorylate LRP6 directly. In contrast to the known PPPSPxS Ser/Thr kinases, tyrosine phosphorylation by Src and Fer negatively regulates LRP6-Wnt signalling. Epistatically, they function upstream of b-catenin to inhibit signalling and in agreement with a negative role in regulating LRP6, MEF cells lacking these kinases show enhanced Wnt signalling. Wnt3a treatment of cells enhances tyrosine phosphorylation of endogenous LRP6 and, mechanistically, Src reduces cell surface LRP6 levels and disrupts LRP6 signalosome formation. Interestingly, CK1c inhibits Fer-induced LRP6 phosphorylation, suggesting a mechanism whereby CK1c acts to de-represses inhibitory LRP6 tyrosine phosphorylation. We propose that LRP6 tyrosine phosphorylation by Src and Fer serves a negative regulatory function to prevent overactivation of Wnt signalling at the level of the Wnt receptor, LRP6.
Extended Tree Transducers in Natural Language Processing

Tree transducers are finite-state devices computing relations on trees. Their study was initiated by Thatcher (1970) and Rounds (1970), who established the classical top-down tree transducers that process the input tree from the root towards the leaves. Shortly afterwards, Baker (1973) introduced the bottom-up tree transducers that process the input tree from the leaves towards the root in analogy to the top-down and bottom-up tree automata (Thatcher, 1973). Due to applications in syntax-directed semantics (Fulop and Vogler, 1998), tree transducers were extensively studied in the following years as detailed in (Gecseg and Steinby, 1984) and (Gecseg and Steinby, 1997). Notable extensions to the original top-down tree transducers include the top-down tree transducers with regular look-ahead by Engelfriet (1977), the attributed tree transducers of Fulop (1981), and the macro tree transducers by Courcelle and Franchi-Zannettacci (1982) and Engelfriet and Vogler (1985). In statistical machine translation (Koehn, 2009), syntax-based models (Chiang, 2010) [i.e., models that translate from or to syntax trees] have recently seen a lot of progress. It was identified already by Eisner (2003) that the classical linear top-down and bottom-up tree transducers cannot properly handle phenomena (such as rotation) that occur during the translation between natural languages. This result was presented for synchronous contextfree grammars [SCFG] (Chiang, 2006), which is a formalism similar in spirit to (and essentially equally expressive as) the syntax-directed translation schemata by Aho and Ullman (1969), which were later refined to the more general bimorphism approach by Arnold and Dauchet (1982). Instead Eisner (2003) proposes synchronous tree
Potential energy functions: From consistent force fields to spectroscopically determined polarizable force fields

We review our methodology for producing physically accurate potential energy functions, particularly relevant in the context of Lifson's goal of including frequency agreement as one of the criteria of a self‐consistent force field. Our spectroscopically determined force field (SDFF) procedure guarantees such agreement by imposing it as an initial constraint on parameter optimization, and accomplishes this by an analytical transformation of ab initio “data” into the energy function format. After describing the elements of the SDFF protocol, we indicate its implementation to date and then discuss recent advances in our representation of the force field, in particular those required to produce an SDFF for the peptide group. © 2003 Wiley Periodicals, Inc. Biopolymers: 383–394, 2003