Miracle-dz/UniFAR-FTUs huggingface dataset:
Computer-Aided Detection of Mediastinal Lymph Nodes using Simple Architectural Convolutional Neural Network

Lung cancer is the most common and the deadliest cancer in the world. Lung cancer staging usually was done by radiologist by detecting mediastinal lymph node (LN) enlargement. Mediastinal LN is difficult to be detected visually due to its low contrast to the surrounding tissues, various size and shape, and sparse location. Therefore, computer-aided detection (CADe) system has been developed as a tool for radiologist to detect mediastinal LN automatically. The state of the art mediastinal LN CADe system use complex architectural convolutional neural network (CNN). However, more simple architecture of the CNN is needed to reduce the computational complexity of the CADe system, especially if the system was intended to be used in a regular computer. Therefore, in this experiment we used simple architectural 2D CNN which is converted to fully convolutional network (FCN) to detect mediastinal LN candidate in a stack of CT images. Then, the mediastinal LN candidates were classified using 3D CNN to reduce the false positive (FP). The best performance of this CADe system was 65% of sensitivity at 5 FP/patient.
Numerical Approach to a Nonlocal Advection-Reaction-Diffusion Model of Cartilage Pattern Formation

We propose a numerical approach that combines a radial basis function (RBF) meshless approximation with a finite difference discretization to solve a nonlinear system of integro-differential equations. The equations are of advection-reaction-diffusion type modeling the formation of pre-cartilage condensations in embryonic chicken limbs. The computational domain is four dimensional in the sense that the cell density depends continuously on two spatial variables as well as two structure variables, namely membrane-bound counterreceptor densities. The biologically proper Dirichlet boundary conditions imposed in the semi-infinite structure variable region is in favor of a meshless method with Gaussian basis functions. Coupled with WENO5 finite difference spatial discretization and the method of integrating factors, the time integration via method of lines achieves optimal complexity. In addition, the proposed scheme can be extended to similar models with more general boundary conditions. Numerical results are provided to showcase the validity of the scheme.
Active vibration control development in ultra‐precision machining

This study presents a combined feedback–feedforward adaptive regulator applied to an active vibration control tool holder platform to contain the effect of machining vibrations. The proposed mechatronic solution can be integrated in a milling machine tool as an interface between the beam (Z-axis) and the tool holder. The aim is to counteract vibrations in the broadband frequency range (100 Hz–900 Hz), controlling the tool position in real time. The active vibration control system is based on the harmonic steady-state concept due to the sinusoidal representation of the disturbance signals. The study focuses on the regulator architecture and the main logics applied to satisfy the required performance. A full investigation is executed through simulations and experimental campaigns, proving the disturbance reduction. The active vibration control system is implemented on a 4-axis machine tool and validated using multitonal disturbances. The system is evaluated in compensating a set of undesired effects, such as vibrations generated by unbalanced tools or hard material cutting processes. The obtained results show a maximum reduction of the vibration amplitude by 43.7% at the critical frequency.
A SCADA approach for Micro-grid based on Platform as a Service (PaaS) Delivery Model of Cloud Computing

Based on the current development of smart grid, this paper makes an in-depth exploration on the interoperability of microgrid platforms, mainly on the interoperability among institutions. Conduct a hierarchical analysis of different requirements to study different levels of interoperability. In this paper, a private hybrid cloud based SCADA architecture is found based on the interoperability of the microgrid platform while ensuring security limitations. Because data collection and critical monitoring are limited by time in the grid, not as critical monitoring and data collection can be accessed by private cloud partners only after being selected. And the main SCADA function is still controlled by the local server, so the cloud architecture is mixed, and this communication is a service delivery model, a model based on cloud computing.
Algoritma Perencanaan Jalur Kendaraan Otonom berbasis Hibridisasi Algoritma BFS dan Path Smoothing

Abstrak – Pada penelitian ini dirancang algoritma alternatif untuk perencanaan jalur kendaraan otonom. Algoritma yang diusulkan adalah hibridisasi dari algoritma Breadth First Search (BFS) dan algoritma path smoothing (BFS – path smoothing). Berdasarkan pengamatan dari hasil pengujian, keuntungan dari algoritma BFS adalah dapat memberikan solusi yang menuju solusi optimal, tetapi memiliki kelemahan dari waktu komputasi yang tinggi. Agar diperoleh solusi yang optimal, maka jalur yang dihasilkan oleh algoritma BFS akan diproses lebih lanjut oleh algoritma path smoothing. Walaupun algoritma BFS - path smoothing memiliki waktu komputasi yang tinggi, tetapi untuk tujuan mendapatkan solusi yang optimal, waktu komputasi BFS – path smoothing masih lebih rendah daripada algoritma RRT* untuk mendapatkan solusi yang optimal. Algoritma RRT* adalah salah satu algoritma yang umum digunakan untuk perencanaan jalur pada kendaraan otonom. Proses hibridisasi ini dilakukan dengan cara menjalankan algoritma BFS terlebih dahulu untuk memberikan solusi awal. Solusi awal tersebut kemudian ditingkatkan kualitasnya menggunakan algoritma path smoothing untuk memperoleh solusi yang optimal. Pengujian algoritma BFS-path smoothing ini dilakukan secara simulasi menggunakan beberapa kasus benchmark yang ada, yaitu lingkungan narrow, maze, trap dan clutter. Kriteria optimalitas yang dibandingkan adalah biaya jalur dan waktu komputasi. Pada pengujian, performansi dari algoritma BFS-path smoothing dibandingkan dengan performansi dari algoritma RRT*. Kami menunjukkan bahwa algoritma yang diusulkan dapat menghasilkan output jalur dengan kualitas yang lebih tinggi daripada jalur yang diproduksi oleh RRT*. Kata Kunci : Beadth First Search, path smoothing, perencanaan jalur, pengujian simulasi, RRT*
Towards a Typology of Sustainability Practices: A Study of the Potentials and Challenges of Sustainable Practices at the Firm Level

International awareness and demands for sustainable development have pushed the sustainability narrative into the forefront of the United Nations’ Sustainable Development Goals (SDGs). As a result, the call for sustainable business practices has never been greater. While businesses are both needed and eager to contribute to sustainable development, current literature lacks insights into how businesses can practice sustainability. This paper aims to fill this gap and develop an understanding of the different categories of sustainability practices that firms adopt, and the potentials and challenges associated with them. Based on a qualitative multiple case study, we identify four categories of sustainability practices including inspiring and informing, productizing, co-creating and system building. We integrate these findings into a sustainability maturity typology, proposing that these four practices are associated with an increasing intensity of sustainability intention, so that firms realize increasing levels of sustainability in the focal business practices as they move from inspiring and informing through to system building. The article concludes by arguing that there is no generic “one size fits all” approach to support sustainability practices as approaches need to fit a firm’s sustainability maturity.
Trends and change points in surface and bottom thermal environments of the US Northeast Continental Shelf Ecosystem

Decadal scale change in temperature has had dramatic effects on the productivity and organization of marine ecosystems, in particular, continental shelf ecosystems, which are responsible for much of the world's food security (Free et al., 2019). Temperature, and the associated effects on thermohaline stratification and circulation, plays a major role in the distribution and productivity of marine biota. Marine ecosystems depend on thermally influenced vertical mixing to resupply nutrients in surface waters, which Received: 30 August 2019 | Revised: 13 April 2020 | Accepted: 15 May 2020 DOI: 10.1111/fog.12485
An updated system for the targeted mutagenesis of the psbDI:psbC operon in Synechocystis sp. PCC 6803: mutations targeting Asp460 in CP43 of Photosystem II reduce oxygen-evolving activity and perturb electron transfer in the quinone-Fe-acceptor complex

ABSTRACT The cyanobacterium Synechocystis sp. PCC 6803 is widely used as a model organism to study Photosystem II (PS II) of oxygenic photosynthesis. In response to inherent genetic instability in cyanobacteria we re-sequenced our strain of Synechocystis sp. PCC 6803, designated as Glucose Tolerant Otago 1 (GT-O1), to establish its genomic background [Morris JN, Crawford TS, Jeffs A, Stockwell PA, Eaton-Rye JJ, Summerfield TC. 2014. New Zealand Journal of Botany. 52:36–47]. Here we have constructed a mutagenesis system to enable us to study roles of the D2 and CP43 PS II reaction centre proteins in the GT-O1 strain. A ΔDIC/ΔDII deletion mutant was assembled in which the psbDI/psbC operon encoding D2 and CP43 was replaced by a chloramphenicol-resistance cassette and psbDII, encoding a second copy of D2, was replaced with a kanamycin-resistance cassette. A DIC+/DII– control strain was constructed by reintroducing the psbDI/psbC operon under selection provided by a spectinomycin-resistance cassette. In this system mutations can be introduced following in vitro mutagenesis of the psbDI/psbC operon. To test our system, we introduced mutations at the CP43 residue Asp460 which is hydrogen bonded to Arg-24 and Arg-28 of the PsbT low-molecular-weight subunit of PS II that is found at the monomer–monomer interface of the PS II dimeric complex in the thylakoid membrane. While the control strain showed a similar phenotype to wild type our CP43 mutants (D460A, D460E and D460N) exhibited a reduction of oxygen-evolving activity and alteration in electron transfer between the primary (QA) and secondary (QB) plastoquinone electron acceptors of PS II.
Cost Analysis of Indonesia Case Based Groups (INA-CBGs) Tariff for Stroke Patients

The INA-CBG’s (Indonesia Case Based Groups) package rate implementation for National Health Insurance Program member since 1 st January 2014 suffering from stroke has forced all hospitals in Indonesia to do a quality control and efficient service cost. Stroke, one of the catastrophic diseases often accompanied with some of its comorbid factors, requires high treatment cost. Thus, a cost analysis study is needed to prevent hospital loss. This study was aimed at determining the suitability of cost between the real cost of stroke therapy and the Indonesian Case-Based Groups (INA-CBG) rate according to the Ministry of Health Decree number 69 of 2013. This study was an observational study with a cross-sectional design. Data collection was done retrospectively. Study subjects were all that hospitalized strokes of patients who were members of the National Health Insurance and also met the inclusion and exclusion criteria registered between January to June 2014. The study data were in real direct medical costs analyzed for its suitability with the INA-CBG's rate. Descriptive statistical tests and t-tests were used to analyze the data. The results showed that the average real cost of the first-class hospitalization was higher than INA-CBG's rate for cerebral infarction and for unspecified stroke, with insignificant discrepancies. The average real cost of second class hospitalization was lower than INA-CBG's rate for cerebral infarction, otherwise the average cost was higher than INA-CBG's rate for unspecified stroke, with insignificant discrepancies. The average real cost of third class hospitalization was lower than INA-CBG's rate for cerebral infarction and for unspecified stroke, with significant discrepancies. Most of the average costs were higher than the INA-CBG rate. Thus, the hospital is not capable of managing a stroke of cost-based treatment on INA-CBGs. The hospital has suffered losses. INA-CBG's rate of stroke treatment needs to be evaluated.
Isolation, Characterization and Sensitivity Pattern of Staphylococcus aureus Isolated from Milk Samples in Khartoum State–Sudan

One of the most frequent diseases occurring within lactating animals is mastitis. It is a bacterial disease that causes the infection and inflammation of udder tissue which ultimately affects the quality of milk consumed and leads to reduced milk production (Preethirani et al., 2015). Among different mastigens frequently reported are Streptococcus agalactiae, Staphylococcus aureus, Escherichia Coli, Klebsiella pneumoniae, and Streptococcus uberis. Two most problematic bacteria are
Studies towards novel aldolase mimics

The present thesis is concerned with a novel approach towards the design of artificial aldolase mimics. The introductory chapter provides an overview of previous strategies and approaches that have been employed in the design and synthesis of artificial enzyme systems. Following on from a brief introduction to previous work within our own group, Chapter 2 presents and discusses the preparation and reactivity of a number of novel polymeric systems which are capable of catalysing the aldol reaction. The strategy adopted consisted of the preparation of regiochemically defined alternating co-polymers wherein each of the two monomers, an N-alkylated maleimide and a para carboxamide styrene possessed either a carboxylic acid or an amino group and were hence capable of functioning as Class I aldolase mimetics. A complementary strategy has also been undertaken wherein both functional groups involved in catalysis are attached to a single monomer, and subsequently subjected to ring opening metathesis polymerisation. This approach guaranteed attachment of these two groups in a fixed 1:1 ratio and had the added advantage of acting as organocatalysts in their own right. For this purpose, systems based on 7- azabicyclo[2.2. 1]hept-2-ene, tropane alkaloid like derivatives and a functionalised norbornene were studied. Preliminary work towards functionalised bispidinone derivatives were also considered within this framework. Chapter 3 provides a formal description of the detailed experimental results and procedures used.
Investigating sand quality effect on concrete strength: a case of Debre Markos and its vicinities

Abstract This research aimed to investigating sand quality effect on compressive strength of concrete. All sand samples were tested for silt and clay contents, organic impurities and chemical composition in accordance with ASTM and concrete cubes were casted with mix ratio of 1:2:3 and tested for compressive strength at age of 7 and 28 days. Aliyas (5.33%) and Kuye (12.18%) sand had the minimum and maximum silt content, respectively. Chemical composition of Abay Wodehimado, Aliyas and Abay Wodeyamado sand sources, SiO2 + Al2O3 + Fe2O3, is testified pozzolana class F as per ASTM C-618 and the loss of ignition, MgO, Na2O, and K2O values meet the standard requirement. Accordingly, Kuye, 19.972 MPa, and Abay Wodeyamado, 28.957 MPa, resulted the lowest and highest compressive strength, respectively. It is concluded that sand found in Debre Markos Town and its surrounding contain silt and clay content and organic impurities that exceed the allowable limits and it resulted significant reduction in concrete strength. It is recommended that the concrete mix design in the city should always consider the strength reduction due to presence of these impurities and gradation to ensure that target strength of the resultant concrete is achieved.
Rola edukacji w kształtowaniu postaw sukcesyjnych studentów kierunków ekonomicznych

The paper presents results of the study dedicated to determining attitudes towards succession among economic faculty students. Its purpose has been determined twofold. First it aims at analysing whether young people are interested in becoming a successor in the companies run by their families, second the paper aims at analysing the possibilities and tools with which formal education can affect attitudes towards succession. The study, in its theoretical part, refers to a number of works dedicated to family businesses and entrepreneurship. Following this, in the empirical part, the results of the research conducted among 142 economic faculty students from Polish family businesses, studying at three Polish universities: Warsaw School of Economics, Lomza State University of Applied Sciences, and University of Gdansk were presented. The findings demonstrate that the interest in succession, compared to other career opportunities, is relatively low. One of the potential determinants might be the programs of education that have been implemented by these particular universities.
Advances in Quaternary Studies: The Contribution of the Mammalian Fossil Record

Explaining the multifaceted, dynamic interactions of the manifold factors that have modelled throughout the ages the evolutionary history of the biosphere is undoubtedly a fascinating and challenging task that has been intriguing palaeontologists, biologists and ecologists for decades, in a never-ending pursuit of the causal factors that controlled the evolutionary dynamics of the Earth’s ecosystems throughout deep and Quaternary time. [. ]
Analytical difficulties for determination of acesulfame K in chocolate products

Sweeteners are substances used as a dietary supplement to replace sugar. Consumers are concerned about the high levels of sugar, calories and cariogenicity in confectionery products, which is why the popularity of the so-called. „Light“ products and „sugar-free“ products. Acesulfame K is a synthetic sweetener about 200 times sweeter than sugar. In the present work, an analysis of acesulfame K in cocoa and chocolate products was performed. For the determination of sweeteners acesulfame K, saccharin and aspartame in foodstuffs, a standardized reverse phase high performance liquid chromatography method with UV detection was used. A cocoa matrix-specific compound was observed in all chocolate products analyzed for acesulfame K. Interference did not correspond to acesulfame K on the UV spectrum and could not be removed by two-step purification. The comparison of the spectral characteristics allowed to avoid a misleading result for the presence of acesulfame K in chocolate and cocoa products.
The profile of erythrocyte enlargement due to imported cases of Plasmodium vivax infection: its impact to the patient and the community

Background: Imported cases of malarial vivax also induce erythrocyte enlargement. The size of enlargement depend on the size of the parasite inside the cells. The aim of the study was to examine 20 slides of positive malaria vivax and seek for erythrocyte infected malaria and measure the size of enlarged cells and its shape. As a comparison, a number of normal erythrocyte also evaluated for its size and shape. Methods: This simple cross sectional design of microscope based study was conducted in Parasitology lab, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta-Indonesia, from January to June of 2019. All data collected and further processed using SPSSTM. Results: A total number of 982 erythrocyte infected with P. vivax were examined individually. Those number consist of 243 immature trophozoite, 231 mature trophozoite, 251 micro-gametocyte, and 257 macrogametocyte. As a comparison also being examined 70 normal erythrocyte. Each erythrocyte infected with malaria vivax parasite enlarge to some extent, had irregular shape and the size varied based on the stage of the parasite inside the cells. Discussion: This enlarged erythrocyte is prone to cell sequestration and lysis, a condition that leads to anemia. Anemia affect not just the host but also the community. Proper management of malaria will reduce the burden to the community. Conclusions: Enlarged infected erythrocyte due to malaria vivax can cause anemia with effect to the host and also to the community.
Future cities’ architecture, architecture for active and healthy ageing

Preamble. The worldwide trend of population ageing and in particular at European level produces paradigm shifts from which architecture is not an exception. According to UN, the percentage of older people (65+) will increase from 9% in 2019 to 16% in 2050 At the European level, the ageing trend is even more pronounced, in 2050 it is estimated that the percentage of older adults will reach 28%. This trend of demographic ageing is accompanied by the trend of urbanization. Objective. The paper investigates interdisciplinarly the way in which the architecture of the cities can intelligently support an active and healthy ageing, bringing into discussion the perspective of the age in the architecture. Preliminary studies. The paper starts from the relation of the concept of age-friendly with cities, architecture, communities, public space and is based on a critical appraisal of the literature in this research niche. Materials and Methods. The research is interdisciplinary, architecture-medicine-psychology-social gerontology-kinetotherapy, describing the aspects of ageing that architecture must take into account. Case studies are used, moving from residential to public space. Results: The present research proves the importance of the built environment both urban level and architectural object for a healthy lifestyle and a continuous participation in the city life. Models of good practice in Western Europe that provide opportunities for health, participation and security are revealed. Conclusions. The perspective of the age in architecture represents a change of paradigm essential for adapting the cities of the future. It is imperative the built environment to take into account the new age pyramid, to support the extension of active and healthy life and to contribute to the compression of morbidity. The architecture of the future’a cities should encourage active ageing, optimizing the opportunities for health, autonomy, participation and security in order to increase the quality of life and well-being.
A Guidance to Legacy Systems Modernization

Rapid development of information technology and communication (ICT) has increased the use of information systems in organizations since a decade ago. At the same time, many organizations are still using old information systems to support their business, known as legacy systems. Even though these systems cause technical problems, but they are still used to support service delivery to the customer. These systems are also essential to organizations as they have been operated for many years and possess high business value. The operation of legacy systems cannot be stopped quickly, as it will affect daily business tasks. However, organizations with legacy systems need to think about the ability of the systems to support their future direction. Modernization of legacy systems needs to be implemented to ensure the systems are aligned with global changes as well as improving the competitiveness of the organizations. This study, therefore, reviewed the phases and factors involved in legacy systems modernization to identify gaps and their insufficiencies. There are many studies on legacy systems, but only a few have focused on the overall process of legacy systems modernization. Most studies on legacy systems are technical in nature and refer to specific aspects and phases of modernization. This study aims to provide overall guidance to the organizations in performing legacy systems modernization.