Miracle-dz/UniFAR-FTUs huggingface dataset:
Loss-of-synchronism detection automatics for the networks with distributed generation

Loss-of synchronism processes in the distribution networks with distributed energy resources are considered. They are influenced by new conditions that were not actual for the transmission system. To eliminate the loss-of-synchronism, special detection automatics is used. The application of such an automatics in low-voltage networks with distributed generation is specific. To meet the changed requirements, new algorithm of the automatic device is introduced. It is based on assumptions of voltage range and impedance angle. Equivalent non-synchronous emfs are modeled The method was tested by simulation of the loss-of-synchronism condition that takes place in the distribution networks.
Cooperativities Among Short Amyloid Stretches Within Long Amyloidogenic Sequence Segment

Institute of Systems Biology, Shanghai University, Shanghai 200444, P. R. China CAS-MPG Partner Institute of Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, P. R. China Department of Chemistry, College of Sciences, Shanghai University, Shanghai, P.R. China Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P. R. China Shanghai Center for Bioinformation Technology, Shanghai 200235, China 6 Basic Science Program, SAIC – Frederick, Center for Cancer Research Nanobiology Program, NCI-Fredeick, NIH, Frederick, MD 21702, USA
Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory

Canonical transient receptor potential (TRPC) channels influence various neuronal functions. Using quantitative high‐resolution mass spectrometry, we demonstrate that TRPC1, TRPC4, and TRPC5 assemble into heteromultimers with each other, but not with other TRP family members in the mouse brain and hippocampus. In hippocampal neurons from Trpc1/Trpc4/Trpc5‐triple‐knockout (Trpc1/4/5−/−) mice, lacking any TRPC1‐, TRPC4‐, or TRPC5‐containing channels, action potential‐triggered excitatory postsynaptic currents (EPSCs) were significantly reduced, whereas frequency, amplitude, and kinetics of quantal miniature EPSC signaling remained unchanged. Likewise, evoked postsynaptic responses in hippocampal slice recordings and transient potentiation after tetanic stimulation were decreased. In vivo, Trpc1/4/5−/− mice displayed impaired cross‐frequency coupling in hippocampal networks and deficits in spatial working memory, while spatial reference memory was unaltered. Trpc1/4/5−/− animals also exhibited deficiencies in adapting to a new challenge in a relearning task. Our results indicate the contribution of heteromultimeric channels from TRPC1, TRPC4, and TRPC5 subunits to the regulation of mechanisms underlying spatial working memory and flexible relearning by facilitating proper synaptic transmission in hippocampal neurons.
Minimising energy costs of data centers using high dense heterogeneous systems and intelligent resource management

Recent trends in data centers include on one hand consolidation in large data centers and on the other hand increased number of small edge systems located closer to sources of data or energy. In both cases the key features needed to minimise costs are efficiency, adaptation to changing load and external conditions, and highly autonomous management. Additionally, especially in small edge data centers, efficiency and performance can be often optimized for specific applications. However, dynamic management and achieving efficiency gains for platforms containing a significant number of heterogeneous server nodes in a limited space require appropriate management methods. For example, suspending individual components and proper allocation of nodes becomes crucial to achieve high efficiency. In this paper we present a microserver system and demonstrate how much data center operator can gain in terms of overall costs by applying such systems with a special focus on intelligent power management techniques. In particular, we propose the novel power capping method that takes into account dynamic priorities, efficiency of specific types of heterogeneous server nodes, and impact of power capping on efficiency of specific applications. In this way, it both keeps the requested power usage levels as well as to reduce the overall energy consumption. Proposed architecture and management methods jointly allow to save around 30% of energy costs in a data center.
Semiparametric transformation models for multiple continuous biomarkers in ROC analysis

Recent technological advances continue to provide noninvasive and more accurate biomarkers for evaluating disease status. One standard tool for assessing the accuracy of diagnostic tests is the receiver operating characteristic (ROC) curve. Few statistical methods exist to accommodate multiple continuous‐scale biomarkers in the framework of ROC analysis. In this paper, we propose a method to integrate continuous‐scale biomarkers to optimize classification accuracy. Specifically, we develop semiparametric transformation models for multiple biomarkers. We assume that unknown and marker‐specific transformations of biomarkers follow a multivariate normal distribution. Our models accommodate biomarkers subject to limits of detection and account for the dependence among biomarkers by including a subject‐specific random effect. We also propose a diagnostic measure using an optimal linear combination of the transformed biomarkers. Our diagnostic rule does not depend on any monotone transformation of biomarkers and is not sensitive to extreme biomarker values. Nonparametric maximum likelihood estimation (NPMLE) is used for inference. We show that the parameter estimators are asymptotically normal and efficient. We illustrate our semiparametric approach using data from the Endometriosis, Natural History, Diagnosis, and Outcomes (ENDO) study.
Respiratory Management of Spinal Muscular Atrophy Type 2

ABSTRACT Respiratory insufficiency is the primary cause of morbidity and mortality among patients with spinal muscular atrophy type 2. The primary complications include ineffective cough with decreased airway clearance, nocturnal hypoventilation, diminished lung and chest wall development, and increased risk for pulmonary infection. Respiratory devices including mechanical insufflator–exsufflator and bilevel positive airway pressure are the primary devices of respiratory maintenance and treatment and are associated with decreased morbidity and fewer hospital admissions. This article discusses the primary respiratory complications of spinal muscular atrophy type 2 and the role of respiratory interventions to promote growth and development, improve cough efficacy, reverse nocturnal hypoventilation, and prevent and treat pulmonary infection.
Role of Cyclooxygenase Isoforms and Nitric-Oxide Synthase in the Modulation of Tracheal Motor Responsiveness in Normal and Antigen-Sensitized Guinea Pigs

The effects of selective cyclooxygenase (COX) isoform (COX-1, COX-2) inhibition, alone or in combination with nitric-oxide synthase (NOS) blockade, on in vitro tracheal muscle responsiveness to histamine were investigated in healthy and ovalbumin (OVA)-sensitized guinea pigs. Immunohistochemistry showed that COX-1 and COX-2 are constitutively present in normal guinea pig trachea, particularly in the epithelial layer, and that COX-2 expression is enhanced in OVA-sensitized animals both in epithelial and subepithelial tissues. In normal guinea pigs, SC-560 [5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole] (COX-1 inhibitor) or DFU [5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl)phenyl-2(5H)-furanone] (COX-2 inhibitor) significantly increased the contractile response to histamine, these effects being not additive. NOS inhibition by l-NG-nitro-arginine methyl ester (l-NAME) did not affect histamine-induced contraction but reversed the increase caused by COX-1 blockade while not modifying the enhancement associated with COX-2 inhibition. In guinea pigs subjected to OVA sensitization and challenge, COX-2, but not COX-1, inhibition enhanced the motor responses to histamine without any influence by l-NAME. In normal, but not in sensitized animals, the removal of epithelial layer from tracheal preparations abolished the enhancing action of DFU on histamine-mediated contraction. A COX-2-dependent release of prostacyclin (PGI2), but not prostaglandin E2, was observed in tracheal tissues from normal and OVA-sensitized guinea pigs. In conclusion, both COX-1 and COX-2 are constitutive in guinea pig trachea, and COX-2 expression is enhanced by OVA sensitization; in normal animals, epithelial COX-2 exerts a PGI2-dependent inhibitory control on tracheal contractility, and this isoform is subjected to upstream regulation by epithelial COX-1 and NOS through a complex interplay; and following antigen sensitization, the inhibitory control on tracheal contractility is maintained by COX-2 induced at subepithelial cell sites.
A Family Business Success Map to Enhance the Sustainability of a Multi-Generational Family Business

“Shirtsleeves to shirtsleeves in three generations” [1]. This saying, which originated in the United States of America (USA), refers to the tendency of family-owned enterprises not to be financially sustainable during the reign of the third generation or thereafter. This notion is not unique to the USA and in many countries, this sentiment is echoed. In Brazil, they say: “Pairico, filhonobre, netopobre”. Roughly translated, it means rich father, Abstract
Networked Business Process Management

In the current economy, a shift can be seen from stand-alone business organizations to networks of tightly collaborating business organizations. To allow this tight collaboration, business process management in these collaborative networks is becoming increasingly important. This paper discusses automated support for this networked business process management: automated means to manage business processes that span multiple autonomous organizations. The author starts this paper with a treatment of intra-and inter-organizational business processes to provide a conceptual background for business process management in business networks. The author describes a number of research approaches in this area, including the context of these approaches and the architectures of the automated systems proposed by them. The approaches are described from early developments in the field relying on dedicated technology to current designs based on standardized technology in a service-oriented context. The paper thereby provides an overview of developments in the area of inter-organizational business process management in the spectrum from simple, static business networks to complex, dynamic networks. The author observes that the described BPM research efforts move from pushing new BPM technology into application domains to using BPM to realize business-IT alignment in complex application contexts.
Water Sorption, Solubility, and Color Stability of Giomer Restoratives.

OBJECTIVES This study compared the color stability, water sorption, and solubility of a giomer composite and two nanohybrid composite resins. MATERIALS AND METHODS Disc-shaped specimens (1-mm thickness × 15-mm diameter) of a giomer (Beautifil II, Shofu, Kyoto, Japan) and two nanohybrid (Filtek Z550, 3M ESPE, St. Paul, MN, USA; Tetric N-Ceram, Ivoclar Vivadent, Schaan, Liechtenstein) composites (N = 10) were prepared. Baseline color measurements were taken, and specimens were immersed in water for 28 days. Following immersion, color values were remeasured, and color-change values (ΔE) were calculated. Water sorption and solubility were assessed by mass gain or loss after storage in water for 28 days. Data were analyzed with one-way analysis of variance and Tukey's post-hoc tests (p = 0.05). Pearson's correlation test was used to assess possible correlations between water sorption and solubility, water sorption and color stability, and solubility and color stability (p = 0.05). RESULTS Water sorbtion (%) and color change (ΔE) varied significantly among groups, with Beautifil II exhibiting the highest values (p < 0.001). No statistically significant differences were observed in water solubility values among the groups (p = 0.661); however, a linear, positive correlation was detected between solubility and discoloration (r = 0.368, p = 0.046). CONCLUSION Water sorption and discoloration values of the giomer composite group were significantly higher than those of the nanohybrids tested. CLINICAL SIGNIFICANCE The high levels of water sorption and discoloration of giomer composites are likely to have an adverse effect on esthetic restorations.
Genes y comportamiento de género: azar o necesidad?

El titulo, parcialmente tomado prestado del famoso libro de Monod (1977) pone el dedo en la llaga de la Genetica del Comportamiento: el tema de ambiente versus herencia constituye el nucleo fundamental en esta materia, y, normalmente, da origen a los errores mas basicos. La intencion de este articulo no es desplegar una gran cantidad de informacion sobre los ultimos avances de la genetica. Mi pretension es, quizas, mas modesta desde el punto de vista de los datos, accesibles en la bibliografia especializada, pero algo mas ambiciosa desde el punto de vista de las ideas. La genetica del comportamiento humano plantea especiales dificultades: objeto y sujeto se funden en esta rama de la ciencia, el comportamiento es algo labil y extraordinariamente versatil, y si a ello anadimos las posibles implicaciones sociales que se derivan de su estudio, con la carga emocional, ideologica, y en definitiva, politica, que arrastra, los problemas sobre la complejidad y objetividad en la interpretacion de la informacion resultan evidentes. En la primera parte del articulo tratare sobre el significado del sexo y los atribuidos estereotipos de comportamiento al respecto en el mundo biologico. En la segunda parte, quizas la mas importante, mi intencion es tratar de aclarar dos aspectos fundamentales en la genetica del comportamiento. Una, el “como” funcionan los genes (las ideas de complejidad y de genotipo versus fenotipo). Y dos, el “por que” de esos genes (el significado de nuestra historia evolutiva). Creo que, analizados los datos iniciales bajo este doble prisma, podremos obtener una idea bastante proxima a la realidad, de lo que es y lo que significa, los genes y el comportamiento.
A new taxonomy of insider threats: an initial step in understanding authorised attack

Insider threat represents one of the greatest challenges in the cyber security world. Insider attackers have more privileged and legitimate access to the information and facilities, compared to the outsider attackers. In fact, insider attacker has more accessibilities and higher potential to bring huge damage to the organisation. However, the behaviour of the insider attacker generates many questions to ponder before a new taxonomy is created. Therefore, the main objective of this paper is two-fold: a) to classify the insider threat for better understanding; b) propose a new taxonomy for insider threat with terminologies. To obtain the objective, the process starts with collecting and classifying the evident. Then, this study presents a hybrid insider threat classification based on combining insider threat access, motivation, indicator, types and actions, profile categorisation, methods, and detection techniques. With the insights afforded by looking more closely at conceptual understanding, we describe how classification of insider threat may effectively be used in insider threat detection.
Measuring Young Consumers’ Response to Brand Scandals: A Brand Love Perspective

Abstract In the past few years, brand scandals have become increasingly common in the global marketplace, resulting in significantly declining consumer preferences and purchases for the brand implicated in a scandal. However, the nature of brand scandal and brand love has scarcely been explored. The present study experimentally investigates the effect of type of brand scandals on consumers’ attitude and purchase intentions towards a scandalous brand and examines the impact of brand love on consumer responses towards the scandalous brand. Results suggest that consumers having high brand love have positive attitude and purchase likelihood, while the nature of brand scandals and brand love does not influence consumers’ response for the scandalous brand. Furthermore, results of the study indicate that the two-way interaction effects with the types of brand scandals (intrinsic and extrinsic) and brand love (high/low) on consumer’s behavioural intentions are insignificant.
Visually Induced Motion Sickness in Virtual Environments

Visually induced motion sickness is a syndrome that occasionally occurs when physically stationary individuals view compelling visual representations of self-motion. It may also occur when detectable lags are present between head movements and recomputation and presentation of the visual display in helmet-mounted displays. The occurrence of this malady is a critical issue for the future development and implementation of virtual environments. Applications of this emerging technology are likely to be compromised to the extent that users experience illness and/or incapacitation. This article presents an overview of what is currently known regarding the relationship between visually specified self-motion in the absence of inertial displacement and resulting illness and perceptual-motor disturbances.
A User-centric Approach for Interactive Visualization and Mapping of Geo-sensor Data

Sensor network applications collect and use sensor data from distributed sensor networks and databases. These real-time and time series sensor data are very useful for many location-based systems that manage and browse various kinds of personal spatial information such as digital photograph, travel diary and so on. Such location-based system for personal use requires a user-centric framework that can support intuitive query request and direct sensor data mapping. This paper proposes a user-centric approach for interactive visualization and mapping of geographically distributed sensor data. The overview of the prototype system that we are developing is briefly described. Our approach generates a query for distributed sensor databases based on user's track log. This method produces understandable information from collected sensor data based on GIS (geographic information system) methods.
Hybrid antenna suitable for broadband mobile phone MIMO system

In this paper, a hybrid antenna for suitable MIMO (Multi Input Multi Output) system for the hexa band mobile phone included LTE700 was designed and implemented. Hybrid consists of a monopole and an IFA (Inverted F Antenna). Monopole is fed, and IFA is simultaneously operated by the capacitive coupling of the monopole. Increase of capacitance by the coupling structure can perform both the low frequency resonance and the wide antenna bandwidth. To achieve small size, antenna is used vlade technique. PCB embedded type was applied to antenna design. For verification of this study, we designed hexa band as LTE700, CDMA, GSM900, DCS1800, PCS and WCDMA, and implemented on the bare board that is same size of real board of the handset. VSWR measurement showed within 3:1 over the whole design band. Average gains and efficiencies were measured as -3.74 ~ -1.31dBi and 42.40 ~ 73.91% for proposed antenna. H-plane radiation patterns were almost omni-directional.
Resolution of extreme warpage in ultra-thin molded array packages under High Temperature Storage Life

The semiconductor industry is demanding miniaturization coupled with increased functionality from microelectronic packages. Ultra-thin molded array packages (TMAP) with package thickness ≤ 500 μm are desirable for applications where system integration space is limited. Such ultra-thin packages require careful selection of the epoxy molding compound (EMC) to control strip level and package level warpage. In this work, the ultra-thin MAP package (8 mm × 8 mm) has an EMC thickness of 0.250 ± 0.025 mm, substrate thickness of 0.105 ± 0.025 mm, and 0.076 mm thick die. This package was found to exhibit extreme “smiley-face” warpage (solder balls down) of 160 μm after 175°C, 504 hrs High Temperature Storage Life (HTSL) conditions, resulting in problems with automated package pick-up by the test handler arm during electrical testing. The warpage was permanent and no relaxation was observed even after one month of storage at room temperature. The primary mechanism for this warpage behavior was found to be thermal oxidation of the EMC in HTSL. High temperature causes thermo-oxidative crosslinking leading to densification and shrinkage of the EMC inducing stresses leading to package warpage. Oxidation also changes the coefficient of thermal expansion and elastic modulus of the EMC.
Analysis of Information Security News Content and Abnormal Returns of Enterprises

As information technologies and the Internet have rapidly evolved, businesses have begun to use them to improve communication efficiency within and outside the organization. However, applications of information technologies are accompanied by information delivery, personal data protection, and information security problems. There are potential risks inherent in any application of information technologies. Moreover, with the improvement of networking and computing capabilities, the impact of attacks from hackers and malicious software has also increased. A breach or leakage of important corporate data may not only damage the firm’s image but also sabotage the firm’s operation, resulting in financial losses. In this study, the content of information security news reports was analyzed in an attempt to clarify the association between information security news and corporate stock prices. Methods including decision trees, support vector machines (SVMs), and random forests were used to explore the associations of news related variables with abnormal returns. Results indicate that the news source and the presence of negative words in the news have an impact on abnormal returns.