Miracle-dz/UniFAR-FTUs huggingface dataset:
Two-year outcome in first-episode schizophrenia: predictive value of symptoms for quality of life.

OBJECTIVE Many studies have validated the grouping of schizophrenic symptoms into three independent dimensions: negative, psychotic, and disorganized. Negative symptoms are considered to be an important prognostic indicator, but this clinical observation requires further empirical study, especially with respect to psychosocial functioning. When present at the onset of the first episode, negative symptoms suggest that the patient will develop significant psychosocial impairment. The predictive values of the psychotic and disorganized symptom dimensions, on the other hand, have been less certain. METHOD In this study of 50 first-episode schizophrenic patients, who were mostly neuroleptic-naive at intake, the authors examined the relationship between the severity of these three symptom dimensions (measured by using the Scale for the Assessment of Negative Symptoms and the Scale for the Assessment of Positive Symptoms) at index hospitalization and quality of life at 2-year follow-up. RESULTS Negative symptom severity was positively and significantly correlated with later occupational impairment, financial dependence on others, impaired relationships with friends, impaired ability to enjoy recreational activities, and global assessment of functioning. The magnitudes of correlation between the levels of psychotic symptoms or disorganized symptoms and 2-year quality of life measures were comparatively lower. Analyses using multivariate regression statistics also revealed similar findings. CONCLUSIONS Severity of negative symptoms at index hospitalization may be a portent of poor outcome. In general, severity of psychotic or disorganized symptoms at intake does not appear to predict subsequent quality of life.
CommOnCV: modelling the competencies underlying a curriculum vitae

This paper presents the project CommOnCV, which aims at dealing with the problematics of e---recruitment by considering a new approach based on competency management. The idea consists of allowing a job seeker (respectively a recruiter to identify and formally represent the competencies underlying its Curriculum Vitae (respectively its job offer). These competencies, which allow to make explicit knowledge, skills, abilities, traits and motives acquired by a person (respectively required for a job), are then used to refine the matching process between "supply and demand". In other words, the objective of CommOnCV is to provide to the end-users of websites dedicated to e---recruitment new job-matching services based on competency management. From a technical viewpoint, these competencies are represented by a set of CV's annotations, which are formally represented by using semantic web languages such as RDF/RDFs or DAML+OIL. These annotations, which respect a particular model of competency, are defined according to domain ontologies. These ontologies can be related to a specific sector like Finance/Banking or Healthcare (in this context, the ontology includes the description of jobs and their associated tasks, the description of knowledge, skills and abilities related to these jobs, the organizations of the leader firms, etc.) and/or to a particular enterprise (in this case, the ontology includes the description of more specific tasks exclusively performed by the considered enterprise, organizational, technological and cultural aspects, etc.).
Implication de l’oxygénation cérébrale dans les limitations à l’exercice musculaire des personnes non-entraînées et des sportifs d’endurance

Implication de l’oxygenation cerebrale dans les limitations a l’exercice musculaire des personnes non-entrainees et sportifs d’endurance. L’objectif general de ce travail etait de determiner si l’oxygenation cerebrale etait un facteur de la limitation a l’exercice de type aerobie. Dans un premier temps, nous nous sommes attaches a etudier le role de l’oxygenation cerebrale mesuree par la Spectroscopie dans le proche Infra-Rouge (NIRS) dans la limitation de l’exercice progressif maximal en rampe. Nous avons montre l’existence d’un seuil de declin de l’oxygenation cerebrale associe au point de compensation respiratoire (RCP). L’amelioration de la performance avec une supplementation d’O2 etait liee au decalage de ce seuil a de plus hautes intensites d’exercice chez des sujets actifs (etude 1). Dans un second temps, nous avons montre que ce seuil de declin de l’oxygenation, retrouve aussi chez des sportifs entraines en endurance apparaissait a de plus hautes intensites d’exercice que chez des sujets non-entraines (etude 2). Enfin, nous avons determine l’impact de l’hypoxemie arterielle induite par l’exercice (HIE) des sportifs d’endurance sur l’oxygenation cerebrale au cours d’un exercice maximal en rampe et d’un exercice de temps limite a charge constante. Nous avons ainsi montre que l’oxygenation cerebrale etait augmentee avec la HIE suggerant un effet compensatoire a l’hypoxemie arterielle au cours de l’exercice progressif maximal en rampe. Ceci, n’existait pas au cours de l’exercice de temps limite ne supportant pas l’implication de l’oxygenation cerebrale dans ce type d’exercice (etude 3). Ces travaux ont donc mis en evidence l’implication de l’oxygenation cerebrale dans la limitation de l’exercice maximal en rampe chez des sujets actifs et des sportifs entraines en endurance presentant ou pas une HIE. Toutefois, elle ne semble pas etre un facteur majeur de limitation de l’exercice de temps limite.
Tissue quantification with acoustic radiation force impulse imaging: Measurement repeatability and normal values in the healthy liver.

OBJECTIVE The purpose of this study was to describe the most reliable measurement procedure for acoustic radiation force impulse technology and to define the normal wave velocity values in a healthy liver. SUBJECTS AND METHODS Twenty healthy volunteers underwent acoustic radiation force impulse imaging tissue quantification and were enrolled in this prospective study. All patients were examined by two independent operators at the same time. Twenty-four measurements per subject were obtained. Intraoperator and interoperator evaluations were performed. Statistical comparison of all mean data was performed with Student's t test. A value of p < 0.05 was considered significant. A comparative analysis was performed, and interclass correlation coefficients were calculated. RESULTS The operators obtained 960 measurements. A statistically significant difference was found between the mean shear wave velocity values obtained by one operator deep in the right lobe of the liver and the values obtained on the surface of the right lobe (1.56 vs 1.90 m/s) and between the mean values obtained deep in the right lobe and those obtained deep in the left lobe (1.56 vs 1.84 m/s). The other operator had similar results. The distribution of all mean values obtained by both operators deep in the right hepatic lobe exhibited less dispersion (95% CI, 1.391-1.725) than those obtained on the surface (95% CI, 1.664-2.136). In 77.5% of cases, the shear wave speeds were between 1 and 2 m/s. No statistically significant difference was found in the comparisons performed on the right hepatic lobe by the two operators. The interclass correlation coefficient calculated for measurements deep in the right lobe was 0.87 (p < 0.0001). CONCLUSION Acoustic radiation force impulse imaging quantification of hepatic tissue is more reproducible when applied to the deeper portion of the right lobe of the liver.
Low profile small antenna using ferroelectrics cube based artificial magnetic conductor

We report on a zero-phase reflection of 2D arrays of high κ ferroelectrics cubic ceramics around the magnetic resonance frequency, which can be considered as artificial magnetic conductor (AMC). On the basis of a BaxSr1-xTiO3 (BST) technology with a relative permittivity as high as 850, the performances of a dipole antenna in close to a single layer dielectric AMC were investigated numerically. For this low profile antenna, it is found an enhancement of the directivity by more than twice was achieved owing to the high reflectivity of the AMC layer.
The Impact of Prenatal Care on Fetal and Neonatal Death Rates for Uninsured Patients: A “Natural Experiment” in West Virginia

A three-county program in southern West Virginia was developed by an obstetric practice to deliver prenatal care to a population of uninsured patients. Between January 1984 and December 1986, 1331 (29.4%) of 4534 patients were delivered at a level 2 hospital after prenatal care within the clinic program. The hospital-wide fetal death ratio declined from 11.8 to 7.2 per 1000 live births during the years of clinic operation, a statistically significant reduction (P=.02). Uninsured patients experienced a statistically significant reduction in fetal death ratio during the program, from 35.4 to 7.0 per 1000 live births (P=.02), whereas those covered by medical assistance did not experience a reduction. Privately insured patients also had a significant decrease, from 10.0 to 3.1 per 1000 live births (P < .001). The increasing operating expense, mainly due to rising malpractice insurance premiums, required suspension of the program in December 1986. The fetal death ratio returned to 10.3 deaths per 1000 live births in 1987. Factors that varied significantly during the “clinic” phase included: higher rates of cesarean, diagnosed maternal hypertension, and diabetes mellitus; and lower rates of premature rupture of membranes and non-white population. Other factors, including age over 35 years, postdatism, incidence of twins, incidence of lethal congenital anomalies, and single marital status, did not vary significantly before, during, or after the clinic program. This study identified a high-risk population of patients who did not qualify for medical assistance coverage and were de facto “uninsured. ” The results suggest that prenatal care for this high-risk population of uninsured patients can reduce the fetal death rate.
Analysis of buffer-trapping effects on current reduction and pulsed I-V curves of GaN FETs

Two-dimensional transient analyses of GaN MESFETs are performed in which a three level compensation model is adopted for a semi-insulating buffer layer, where a shallow donor, a deep donor and a deep acceptor are included. Quasi-pulsed I-V curves are derived from the transient characteristics. It is shown that so called current collapse or current reduction is more pronounced for a case with higher acceptor density in the buffer layer, because trapping effects become more significant. It is also shown that the current reduction is more pronounced when the drain voltage is lowered from a higher drain bias during turn-on
5‐HYDROXYTRYPTAMINE IN THE CARDIOVASCULAR SYSTEM: FOCUS ON THE SEROTONIN TRANSPORTER (SERT)

1 The function of the serotonin transporter (SERT) is to take up and release serotonin (5‐hydroxytyptamine (5‐HT)) from cells and this function of SERT in the central nervous system (CNS) is well‐documented; SERT is the target of selective serotonin reuptake inhibitors used in the treatment of CNS disorders, such as depression. 2 The aim of the present review is to discuss our current knowledge of 5‐HT and SERT in the cardiovascular (CV) system, as well as their function in physiological and pathophysiological states. 3 The SERT protein has been located in multiple CV tissues, including the heart, blood vessels, brain, platelets, adrenal gland and kidney. Modification of SERT function occurs at both transcriptional and translational levels. The functions of SERT in these tissues is largely unexplored, but includes modulation of cardiac and smooth muscle contractility, platelet aggregation, cellular mitogenesis, modulating neuronal activity and urinary excretion. 4 Recent studies have uncovered potential relationships between the expression of SERT gene promoter variants (long (l) or short (s)) with CV diseases. Specifically, the risk of myocardial infarction and pulmonary hypertension is increased with expression of the ll promoter, a variant associated with increased expression and function of SERT. The relationship between promoter variants and other CV diseases has not been investigated. 5 Newly available experimental tools, such as pharmacological compounds and genetically altered mice, should prove useful in the investigation of the function of SERT in the CV system. 6 In summary, the function of SERT in the CV system is just beginning to be revealed.
A segmentation method for extraction of main arteries from Coronary Cine-Angiograms

Coronary Cine-Angiogram (CCA) based subjective assessment of vascular malfunction is a preliminary diagnostic method in Cardiac clinical procedures. Even though there are many other medical image modalities available, improving the CCA method to objectively detect and assess the stenosis is a cost effective approach in Cardiac clinical procedures. Segmentation of Coronary Arteries (CA) is a basic and challenging area in such an endeavour. Hence, in this study we proposed a segmentation method to extract the major areas of CA based on Frangi's vessel enhancement filter and region growing segmentation method called flood fill. Experimental results of our proposed segmentation method have clearly proven its ability to extract the main CA almost completely. Moreover this proposed segmentation method possesses 93.73% average segmentation accuracy. Further, it detects the vessel path lines of the segmented frames using a thinning algorithm. The results obtained from this proposed segmentation method can be further enhanced to determine the functional severity of the CA and this study lays a foundation to improve the Coronary Angiogram image modality to do objective diagnosis of stenosis in future.
MUC1 Cytoplasmic Domain Coactivates Wnt Target Gene Transcription and Confers Transformation

The DF3/MUC1 mucin-like transmembrane oncoprotein is overexpressed by most human carcinomas. The MUC1 cytoplasmic domain (CD) binds directly to the Wnt effector, beta-catenin, and colocalizes with beta-catenin in the nucleus; however, the nuclear function of MUC1 is unknown. The present results demonstrate that MUC1 coactivates transcription of beta-catenin-Tcf-binding sites in the pTOPFLASH reporter. Activation of transcription was abrogated by expression of MUC1 with a Y-46->F mutation in the CD that attenuates binding of MUC1 and beta-catenin. We also show that transcription of the Wnt responsive cyclin D1 promoter is activated by MUC1, but not MUC1(Y46F), and that the cyclin D1 gene is upregulated in MUC1-positive cells. In concert with these results, MUC1-induced anchorage-independent growth and tumorigenicity were also abrogated by mutating MUC1 at the Y-46 site. These findings support a model in which the MUC1 functions as a transforming protein by coactivating transcription of Wnt target genes.
ICTNET at Session Track TREC2014

Abstract : In this paper, we describe our solutions of the Session Track at TREC 2014. Our main idea is to re-rank the documents the official supplies as RL1. In order to get good results of the re-ranked documents, we implement the learning to rank model which needs to extract some features. We use the relevance judgments of Session Track TREC 2013 as training set this year and also we use it as testing set by 5- fold cross-validation. The rest of this paper is organized as follows. We detail our models in section 2. Section 3 describes our experiments, including our evaluation results. Conclusions are made in the last session.
Discharge planning from hospital to home.

BACKGROUND Discharge planning is the development of an individualised discharge plan for the patient prior to leaving hospital for home, with the aim of containing costs and improving patient outcomes. It has been suggested that discharge planning can reduce unplanned readmission to hospital. OBJECTIVES To assess the effects of discharge planning for patients moving from hospital to home. SEARCH STRATEGY We searched the Cochrane Effective Practice and Organisation of Care Group specialised register, the Cochrane Controlled Trials Register, MEDLINE (1966 to 1996), EMBASE (1980 to 1996), Sigle (1980 to 1996), Bioethics (1985 to 1996), Health Plan (all available years), PsycLit (1974 to 1996), Cinahl (1982 to 1996), EconLit (1969 to 1996), Social Science Citation Index (1992 to 1996), and reference lists of articles. SELECTION CRITERIA Randomised trials and controlled trials comparing discharge planning with routine discharge for hospital patients. The outcomes were mortality, clinical complications, hospital length of stay, readmissions, discharge destination, general and disease specific health status, functional status, psychological well-being, patient satisfaction, carer satisfaction, carer burden, cost to the health service, patient and family, general practice, and community services. DATA COLLECTION AND ANALYSIS Two reviewers independently extracted data and assessed study quality. MAIN RESULTS Eight studies were included involving 4837 patients. Four studies recruited patients with a medical condition; four recruited patients with a mix of medical and surgical conditions, and one of these recruited medical and surgical patients as separate groups. There was a small reduction in hospital length of stay for elderly medical patients allocated to discharge planning (weighted mean difference -1.01, 95% CI -2.06 to 0.05). The effects of discharge planning on readmission rates were mixed. No statistically significant differences were detected for patient health outcomes. Patients with medical conditions allocated to discharge planning reported increased satisfaction compared with those receiving routine discharge. No statistically significant differences were reported for overall health care costs, although one study reported a significant reduction in readmission costs for medical patients allocated to discharge planning. REVIEWER'S CONCLUSIONS The studies showed mixed results, which may reflect the different study populations and the different ways the intervention was implemented. There is some evidence that discharge planning may lead to reduced hospital length of stay, and in some cases reduced readmission to hospital. There is also some evidence that discharge planning increased patient satisfaction. There was no evidence that discharge planning reduced health care costs; however few studies conducted a formal economic analysis.
NON‐SPECIFIC IRRITANT REACTIONS IN ECZEMATOUS SUBJECTS.

IT is often thought that the uninvolved skin of eczematous subjects may react more readily than normal to non-specific and perhaps quite miid irritant stimuli. This leads to a belief that irritant reactions to patch tests are more liable to occur in eczema patients, particularly during an active phase of their disease, and that particular caution is, therefore, needed in the interpretation of these tests in such patients. These views rest, it seems, more on a basis of general clinical experience than upon considered experimental data. Jordon et al. (1936) made patch tests with \ % and 1 % soaps and obtained 50 % positive results in dermatitis subjects, compared with 14 % in normal people. Beek (1946) in patch testing with 10% soap obtained twice the number of positive results in eczema patients, compared with controls. In contrast to this are the findings of Hansen (1936), who found much less difference between eczema patients and normal subjects in their reactions to soap, except for the occurrence of a few strongly positive reactions to 50 % soap in the eczema group.
Longitudinal Study of Pulmonary Function in Infants With Postviral Chronic Pulmonary Disease

Adenovirus may cause severe injury of the lung parenchyma, characterized by bronchial epithelium necrosis, interstitial inflammation and alveolar damage, producing pathological alterations like bronchiolitis obliterans and a clinical course known as Postviral Chronical Pulmonary Disease (PCPD). Pulmonary function in these patients is characterized by a fixed and severe bronchial obstruction and alteration of the lung elastic recoll. The aim of this study was to characterize the evolution of pulmonary function in infants with PCPD. Pulmonary function tests were retrospectively analyzed in infants initially and after 6 to 34 months (mean 11.7 mo). A Sensormedics 2600 system was used. Tests were done in patients sedated with chloral hydrate. Compliance(Crs) and Resistance (Rrs) of the respiratory system obtained by the occlusion technique, and Maximal Flow at Functional Residual Capacity (VmaxFRC) obtained by the rapid thoracic-abdominal compression technique were analyzed. Vmax FRC was compared with the theoretical values by the Hanrahan's equation. Relation between Peak Tidal Expiratory Flow and Tidal Volume (PTEF/VT) from the Tidal Flow/Volume Curves were also considered. 12 patients (6 males and 6 females) were included. Mean age at first and second study were 14.5 (range 5 to 22), and 26.2 (range 11 to 54) months respectively. Mean time between both studies was 11.7 (range 6 to 34) months. Results:Table
Reading the Begriffsschrift

to give a general idea of the way in which our ideography is handled . Through the present example, moreover, we see how pure thought, irrespective of any content given by the senses or even by an intuition a priori, can, solely from the content that results from its own constitution, bring forth judgements that at first sight appear to be possible only on the basis of some intuition . The propositions about sequences developed in what follows far surpass in generality all those that can be derived from any intuition of sequences. If, therefore, one were to consider it more appropriate to use an intuitive idea of sequence as a basis, he should not forget that the propositions thus obtained, which might perhaps have the same wording as those given here, would still state far less than these, since they would hold only in the domain of precisely that intuition upon which they were based.2
Guidelines for the prevention of sepsis in asplenic and hyposplenic patients

Asplenic or hyposplenic patients are at risk of fulminant sepsis. This entity has a mortality of up to 50%. The spectrum of causative organisms is evolving as are recommended preventive strategies, which include education, prophylactic and standby antibiotics, preventive immunizations, optimal antimalarial advice when visiting endemic countries and early management of animal bites. However, there is evidence that adherence to these strategies is poor. Consensus‐updated guidelines have been developed to help Australian and New Zealand clinicians and patients in the prevention of sepsis in asplenic and hyposplenic patients.
Comparison of the Thermal Stabilities of the αβ Heterodimer and the α Subunit of Avian Myeloblastosis Virus Reverse Transcriptase

Avian myeloblastosis virus reverse transcriptase (AMV RT) is a heterodimer consisting of a 63-kDa α subunit and a 95-kDa β subunit. In this study, we explored the role of the interaction between the α and β subunits on AMV RT stability. The recombinant AMV RT α subunit was expressed in insect cells and purified. It exhibited lower thermal stability than the native AMV RT αβ heterodimer. Unlike the αβ heterodimer, the α subunit was not stabilized by template-primer. These results suggest that interaction between the α and β subunits is important for AMV RT stability.
Phase Transitions in the Achievable Sum-Rate of Symmetric Gaussian Interference Channels

We consider the rate sum of a symmetric Gaussian interference channel in standard format, given by and , with an interference coefficient, and constrained to average power and and distributed as ( ) We provide a complete taxonomy of potentially optimal Gaussian signaling strategies in the entire weak and moderate interference parameter space, delimited by and The strategies seem to lead to the Han and Kobayashi achievable region for the rate sum. We find that the parameter space comprises eight (potentially) optimal transmission regions formed by four pure mode strategies and four transitional strategies. We characterize the boundaries of these pure mode regions and the associated transitional regions.