Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigation of argumental oscillations of a physical pendulum

We report an experimental investigation as well as an intuitive theoretical description of argumental oscillations of a physical pendulum, i.e. a driven pendulum where the driving torque depends explicitly on the angle (argument) of the pendulum. With an idealized analysis, we derive three conditions for the occurrence of sustained argumental oscillations: the first establishes the phase matching of the driving system and the pendulum, the second defines the balance of energy gain and loss, and the third identifies the nature of stabilization of the oscillations. For the experimental investigation, we use a recently established pendulum setup, with a further developed suspension mechanism that essentially eliminates friction from the pivot. The pendulum is equipped with a permanent magnet oriented along the pendulum body and a current carrying solenoid located vertically below the pendulum to facilitate an angular dependent excitation. Through studies of free oscillations, we identify the passive electromagnetic pendulum–solenoid interaction as central for the resulting dynamics of the driven pendulum, e.g. it provides a major mechanism of energy dissipation and it modifies the actual dependency of the pendulum frequency on the maximum angle. For one realization of argumental oscillations (Doubochinski’s pendulum), we report experimental frequency response curves, i.e. the oscillation amplitude and the phase relative to the external torque as a function of the driving frequency for selected harmonics (n = 5–13) of the pendulum frequency. The results show the characteristic signatures of argumental oscillations derived from the idealized model, but also display clear deviations corresponding to the complex nature of the interaction of the pendulum and the solenoid.
INDEKS SERVICE QUALITY PERGURUAN TINGGI BANTEN SERVICE QUALITY INDEX OF BANTEN HIGHER EDUCATION

Banten adalah provinsi paling barat Indonesia yang kaya akan potensi sumber daya alam akan tetapi belum memiliki kualitas sumber daya manusia yang cukup untuk mengelola potensi tersebut. Rendahnya kualitas SDM Banten menyebabkan provinsi ini menjadi provinsi dengan tingkat pengangguran tertinggi kedua di Indonesia. Tujuan utama penelitian ini adalah: 1) Menghasilkan Model Pengukuran Service Quality yang khusus untuk Perguruan Tinggi; 2) Mengukur, menggambarkan, serta membandingkan tingkat kualitas perguruan tinggi di Provinsi Banten; 3) Mengidentifikasi kelemahan dan kekuatan service quality masing-masing perguruan tinggi. [D1] Urgensi penelitian ini adalah: 1) membantu penyelenggara pendidikan tinggi di Banten memperkuat keunggulan bersaing mereka melalui peningkatan Service Quality; 2) Membantu Perguruan Tinggi melihat posisi persaingan berdasarkan Indeks Service Quality ; 3) Membantu perguruan tinggi di Banten, baik PTN dan PTS mengevaluasi kualitas pendidikan mereka untuk perbaikan dan perencanaan strategi pemasaran guna menciptakan keunggulan bersaing. Desain penelitian survei digunakan untuk mendapatkan data yang akan dianalisis menggunakan statistik deskriptif, Correlation, Cronbach’s alpha dan Chi-Square tests . Kuesioner disebar kepada 800 mahasiswa dari delapan perguruan tinggi di lima Kota/Kabupaten di Banten yaitu Serang, Cilegon, Pandeglang, Lebak dan Tangerang. Hasil analisis berupa indeks Sevice Quality delapan Perguruan Tinggi di Banten, baik PTN maupun PTS disajikan dalam artikel ilmiah ini.
Diagnosing Open Cluster Stock 2: Member Candidates and Mass Distribution with Gaia DR2 and LAMOST

We identify 1325 member candidates of the open cluster (OC) Stock 2 using data from Gaia DR2. We use the algorithms Clusterix 2.0 and HDBSCAN to select cluster candidates and further refine the final cluster membership by defining neighbors in 5D phase space (X cp, Y cp, /ϖ, κ · μ δ /ϖ). Among these candidates, less than half have G, G BP, and G RP extinctions from Gaia. When Gaia extinctions are unavailable, we compute extiction using empirical formulas and E(B − V) = 0.350. We analyze the spatial distribution and mass profile of Stock 2. Our results reveal Stock 2 is still a bound OC and we find evidence of mass segregation. By comparing initial mass functions, the present-day mass function indicates that Stock 2 is a massive stellar cluster with a mass of 4000 M ⊙. The core radius and tidal radius, calculated via the radial density profile and total mass, are 3.97 pc and 22.65 pc, respectively. Common stars between our selected member candidates and the Large Sky Area Multi-Object Fiber Spectroscopic Telescope DR7 medium-resolution catalog give a metalliclity of [Fe/H] = −0.040 ± 0.147.
Primary care genomic research: One eye on the future

The exceptional advances in genomic medicine in the last two decades, since the sequencing of the human genome, have already had a major impact on healthcare in the UK. Until recently this was predominantly in secondary and tertiary care, but we must now integrate ‘mainstream’ genomics in primary care. So far integration has of necessity been empirical, but must progress towards implementation research. We describe recent work undertaken by the RCGP and the NIHR CRN outlining areas where research is needed to fully integrate genomics into routine primary care and secure the future of these exciting developments.
Special Review: The future of Immunotherapy

Summary During the last two decades, two main schools of modern immunotherapy have come to the forefront. The chimeric anti-CD20 antibody rituximab that was introduced for the treatment of refractory follicular lymphoma in 1998 was one of the first examples of the school of passive immunotherapy. Subsequently major and ever more costly efforts were spent on the development of blockbuster monotherapies including other monoclonal but also bispecific antibodies of highly defined specificity and subclass, antibody–drug conjugates (ADCs), as well as ex vivo expanded tumor-infiltrating lymphocytes, chimeric antigen receptor (CAR)-transduced T cells, and TCR-transduced T cells. On the other hand, there is the school that works toward active induction of patient B- or T-cell immunity against antigens of choice, or active tolerance against pathogenic allergens, auto-antigens or allo-antigens. Stradled in between these two approaches is treatment with blockers of T cell checkpoint control, which releases the brakes of T cells that have already responded to antigen. Extensive and detailed insight into the cellular and molecular interactions that regulate specific immune responses is indispensable in order to be able to optimize efficacy and rule out treatment related toxicity. This applies to all types of immunotherapy. Our knowledge of the checks and balances in the immune system is still increasing at an unprecedented pace, fostering ever more effective and specific (combination) immunotherapies and offering a rich harvest of innovative immunotherapies in the years ahead.
Revealing Temozolomide Resistance Mechanisms via Genome-Wide CRISPR Libraries

Glioblastoma is a severe type of brain tumor with a poor prognosis and few therapy options. Temozolomide (TMZ) is one of these options, however, with limited success, and failure is mainly due to tumor resistance. In this work, genome-wide CRISPR-Cas9 lentiviral screen libraries for gene knockout or activation were transduced in the human glioblastoma cell line, aiming to identify genes that modulate TMZ resistance. The sgRNAs enriched in both libraries in surviving cells after TMZ treatment were identified by next-generation sequencing (NGS). Pathway analyses of gene candidates on knockout screening revealed several enriched pathways, including the mismatch repair and the Sonic Hedgehog pathways. Silencing three genes ranked on the top 10 list (MSH2, PTCH2, and CLCA2) confirm cell protection from TMZ-induced death. In addition, a CRISPR activation library revealed that NRF2 and Wnt pathways are involved in TMZ resistance. Consistently, overexpression of FZD6, CTNNB1, or NRF2 genes significantly increased cell survival upon TMZ treatment. Moreover, NRF2 and related genes detected in this screen presented a robust negative correlation with glioblastoma patient survival rates. Finally, several gene candidates from knockout or activation screening are targetable by inhibitors or small molecules, and some of them have already been used in the clinic.
Constructing the Industrial Prosperity Index Based on Big Data of Enterprise Electricity

This paper is mainly based on the big electric power data of 5900 industrial enterprises above designated size in Shanghai. By combining a complex network and a hidden Markov model, the prosperity index of 164 medium-sized industries in Shanghai is constructed. Specifically, we use complex networks to describe the correlation between different industries, in order to mine the upstream and downstream drivers that affect industrial power consumption, and on this basis, consider the external factors that affect power consumption to establish a hidden Markov model that predicts changes in power consumption in the industry. Further, we use the state probability output by the Hidden Markov Model to define the industrial prosperity index, hoping that the index can fully reflect the economic operation of various industries in Shanghai and become a “barometer” and “wind vane” for economic development.
The effect of technology-organization-environment on adoption decision of big data technology in Thailand

Big data technology (BDT) is being actively adopted by world-leading organizations due to its expected benefits. However, most of the organizations in Thailand are still in the decision or planning stage to adopt BDT. Many challenges exist in encouraging the BDT diffusion in businesses. Thus, this study develops a research model that investigates the determinants of BDT adoption in the Thai context based on the technology-organization-environment (TOE) framework and diffusion of innovation (DOI) theory. Data were collected through an online questionnaire. Three hundred IT employees in different organizations in Thailand were used as a sample group. Structural equation modeling (SEM) was conducted to test the hypotheses. The result indicated that the research model was fitted with the empirical data with the statistics: Normed Chi-Square=1.651, GFI=0.895, AFGI=0.863, NFI=0.930, TLI=0.964, CFI=0.971, SRMR=0.0392, and RMSEA=0.046. The research model could, at 52%, explain decision to adopt BDT. Relative advantage, top management support, competitive pressure, and trading partner pressure show significant positive relation with BDT adoption, while security negatively influences BDT adoption.
The Role of Functional Group on the Exfoliation of Clay in Poly(L-lactide)

A new method was attempted to improve the interaction between poly(L-lactide) (PLLA) with a commercially available organoclay, Cloisite 25A (C25A), which was functionalized with (glycidoxypropyl)trimethoxysilane to introduce epoxy groups, and is referred to as twice-functionalized organoclay (TFC). Tethering PLLA molecules to the epoxy groups on the surface of the TFC was attempted by melt compounding. X-Ray diffraction and transmission electron microscopy images showed that fully exfoliated PLLA/ TFC nanocomposites were prepared successfully.
Investigating the validity of the Wong and Law Emotional Intelligence Scale in a Nepali student sample

This paper investigates the cross-cultural validity of the WLEIS. Two samples of university students were recruited: 504 from a Nepali University and 260 from a UK university. In relation to culture, SEM analyses provided support for the scale's configural invariance and the configural, metric, and scalar invariance of two if its subscales. Evidence for measurement invariance was also found in relation to gender in both samples. Tentative analyses suggested that the correlation between self and other emotion appraisal was stronger among UK participants and that UK participants scored higher on the Other Emotion Appraisal subscale. No gender differences on emotional intelligence were found in the Napali sample, while among UK students, males scored higher on Regulation of Emotion and lower on Other Emotion Appraisal than females. In the Nepali sample, science students scored lower on various aspects of emotional intelligence than humanities students.
PROTONATION OF METALLOCENES BY STRONG ACIDS. STRUCTURE OF THE CATION

Ferrocene recently has been shown to form a stable complex salt of composition (C_(10_H_(10)Fe•HAlCl_4) in the presence of aluminum chloride and hydrogen chloride. This finding, together with the suggestion that the transition state for electrophilic substitution of ferrocene, ruthenocene and osmocene may involve initial interaction of the electrophile with the metal atom, prompted us to examine then.m. r. spectra of these moetallcenes in media of high acidity.
Diagnosekriterien bei Multipler Sklerose: ein Update

Zusammenfassung Neben der klinisch-neurologischen Untersuchung spielt auch die MRT in der Diagnostik und der Verlaufsbeurteilung der Multiplen Sklerose eine wesentliche Rolle. In dieser Übersicht werden die mit der 2017er-Revision der McDonald-Kriterien einhergehenden Änderungen erläutert und differenzialdiagnostische Aspekte, sog. „green flags“ und „red flags“, dargestellt.
GaN Schottky diode ultraviolet detectors grown by molecular beam epitaxy

Vertical geometry Schottky barrier photodiodes have been fabricated on n-GaN films grown by molecular beam epitaxy (MBE). Vertical mesas were fabricated by RIE and Schottky barriers were achieved by depositing Ni/Pt/Au metal contacts. I-V measurements show near ideal diode behavior, with reverse saturation current density of 1 X 109 A/cm2. Doping concentration and barrier height were determined to be 9 X 1016 cm-3 and 1.0V respectively, using C-V measurements. The diodes were then evaluated as UV photodiodes. The responsivity was measured to be 0.18A/W, corresponding to a quantum efficiency of 70 percent. Spectral response showed a sharp transition at 365 nm, and more than five orders of magnitude visible light rejection. Low frequency noise measurements indicate that 1/f noise is the dominant source of noise. The detectivity was determined to be 1.3 X 10-9 W/Hz1/2.
The Relationship between Posttreatment Smile Esthetics and the ABO Objective Grading System: Class I Extraction versus Non-Extraction Cases.

Objective This study aimed to evaluate the relationship between the components of the objective grading system developed by the American Board of Orthodontics (ABO) and smile esthetics in Class I extraction vs non-extraction cases. Methods A total of 40 extraoral smile images of orthodontically treated (20 extraction and 20 non-extraction) cases in the age group of 13-30 years and Class I skeletal malocclusion with an average mandibular plane angle were selected. Smile images were rated only by the orthodontist, and this panel included 12 members. Scoring of post-treatment dental casts and panoramic radiographs of each patient was performed by 1 investigator per the guidelines of the ABO grading system. The Pearson correlation coefficient and logistic regression analysis were used to ascertain whether the scores of the ABO grading system could foretell whether a smile would be "attractive" or "unattractive. " Results The correlation between all the criteria of the ABO grading system and attractiveness of the smile was extremely weak. The r values ranged from -0.53 to 0.37 for extraction cases and -0.63 to 0.003 for non-extraction cases (p>0.05). Neither individual parameters nor total scores of the ABO grading system could predict whether the smile was attractive or unattractive in either group. Conclusion No correlation was found between post-treatment ABO grading and smile esthetics in patients with extraction or non-extraction. Hence, this study recommends that ancillary soft tissue variables have to be incorporated into the grading system to evaluate a smile.
Navigating changes in Clostridioides difficile prevention and treatment

Clostridioides difficile (C. difficile, previously known as Clostridium difficile) infections are a major health care concern. The Centers for Disease Control and Prevention (CDC) estimates that C. difficile causes almost half a million illnesses in the United States yearly, and approximately 1 in 5 patients with a C. difficile infection (CDI) will experience 1 or more recurrent infections. The incidence of infection has risen dramatically in recent years, and infection severity has increased due to the emergence of hypervirulent strains. There have been noteworthy advances in the development of CDI prevention and treatment, including a growth in the understanding of the role a patient’s gut microbiome plays. The 2017 Infectious Diseases Society of America (IDSA) guidelines made a significant change in treatment recommendations for first time CDI episodes by recommending the use of oral vancomycin or fidaxomicin in place of metronidazole as a first-line treatment. The guidelines also included detailed recommendations on the use of fecal microbiota transplant (FMT) in those patients who experience 3 or more recurrent CDI episodes. A number of novel therapies for the treatment of CDI are in various stages of development. Treatments currently in phase 3 trials include the antibiotic ridinilazole, the microbiome products SER-109 and RBX2660, and a vaccine. All of these agents have shown promise in phase 1 and 2 trials. Additionally, several other antibiotic and microbiome candidates are currently in phase 1 or phase 2 trials. A qualitative review and evaluation of the literature on the cost-effectiveness of treatments for CDI in the U.S. setting was conducted, and the summary provided herein. Due to the higher cost of newer agents, cost-effectiveness evaluations will continue to be critical in clinical decision making for CDI. This paper reviews the updated CDI guidelines for prevention and treatment, the role of the microbiome in new and recurrent infections, pipeline medications, and comparative effectiveness research (CER) data on these treatments.
Investing in Low-Trust Countries: On the Role of Social Trust in the Global Mutual Fund Industry

Abstract We hypothesize that social trust, in mitigating contracting incompleteness, may have an important effect on the activeness and effectiveness of delegated portfolio management. Using a complete sample of worldwide open-end mutual funds, we find that trust is positively associated with the activeness of funds and that trust-related active share delivers superior performance (e.g., approximately 2% per year for cross-border investments). Moreover, “trust in the market” and “trust in managers” play important yet different roles for different types of cross-border delegated portfolio management. Our results suggest that trust acts as a fundamental building block for delegated portfolio management.
Differential scanning calorimetry characterization of urea–formaldehyde resin curing behavior as affected by less desirable wood material and catalyst content

Differential scanning calorimetry was applied to investigate the curing behavior of urea–formaldehyde (UF) resin as affected by the catalyst content and several less desirable wood materials (e.g., wood barks, tops, and commercial thinnings). The results indicate that the reaction enthalpy of UF resin increased with increasing catalyst content. The activation energy and peak temperature of the curing UF resin generally decreased with increasing catalyst content at lower levels of catalyst content. However, with further increases in catalyst content, the changes in the activation energy and peak temperature were very limited to nonexistent. The hydrolysis reaction of the cured UF resin occurred during the latter stages of the curing process at both lower level ( 0.7%) catalyst contents. This indicates that there existed an optimal range of catalyst content for the UF resin. The curing enthalpy of the UF resin decreased with increasing wood raw materials present due to the effect of diffusion induced by the wood materials and the changes in the phase of the curing systems. This suggests that the curing reactions reached a lower final degree of conversion for the wood–resin mixtures than for the UF resin alone. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 98: 2027–2032, 2005
Molecular composition and volatility of multi-generation 
products formed from isoprene oxidation by nitrate radical

Abstract. Isoprene oxidation by nitrate radical (NO3) is a potentially important source of secondary organic aerosol (SOA). It is suggested that the second or later-generation products are the more substantial contributors to SOA. However, there are few studies investigating the multi-generation chemistry of isoprene-NO3 reaction, and information about the volatility of different isoprene nitrates, which is essential to evaluate their potential to form SOA and determine their atmospheric fate, is rare. In this work, we studied the reaction between isoprene and NO3 in the SAPHIR chamber (Jülich) under near atmospheric conditions. Various oxidation products were measured by a high-resolution time-of-flight chemical ionization mass spectrometer using Br− as the reagent ion. They are grouped into monomers (C4- and C5-products), and dimers (C10-products) with 1–3 nitrate groups according to their chemical composition. Most of the observed products match expected termination products observed in previous studies, but some compounds such as monomers and dimers with three nitrogen atoms were rarely reported in the literature as gas-phase products from isoprene oxidation by NO3. Possible formation mechanisms for these compounds are proposed. The multi-generation chemistry of isoprene and NO3 is characterized by taking advantages of the time behavior of different products. In addition, the vapor pressures of diverse isoprene nitrates are calculated by different parametrization methods. An estimation of the vapor pressure is also derived from their condensation behavior. According to our results, isoprene monomers belong to intermediate volatility or semi-volatile organic compounds and thus have little effect on SOA formation. In contrast, the dimers are expected to have low or extremely low volatility, indicating that they are potentially substantial contributors to SOA. However, the monomers constitute 80 % of the total explained signals on average, while the dimers contribute less than 2 %, suggesting that the contribution of isoprene NO3 oxidation to SOA by condensation should be low under atmospheric conditions. We expect a SOA mass yield of about 5 % from the wall loss and dilution corrected mass concentrations, assuming that all of the isoprene dimers in the low- or extremely low-volatility organic compound (LVOC or ELVOC) range will condense completely.
Effect of Demagnetization on a Consequent Pole IPM Synchronous Generator

The design and analysis of a permanent magnet synchronous generator (PMSG) are presented. The interior permanent magnet (IPM) rotor was designed asymmetric and with the consequent pole approach. The basis for the design was a series-produced three-phase induction motor (IM) and neodymium iron boron (Nd-Fe-B) cuboid magnets were used for the design. For the partial demagnetization analysis, some of the magnets were extracted and the results are compared with the finite element analysis (FEA).