Miracle-dz/UniFAR-FTUs huggingface dataset:
Cardiac Gated Computed Tomography Angiography Discloses a Correlation Between the Volumes of All Four Cardiac Chambers and Heart Rate in Men But Not in Women

Background: Currently, normal values of the cardiac chambers' volumes are adjusted only for gender and body surface area (BSA). We aim to investigate the association between the heart rate and the volume of each of the four cardiac chambers using cardiac-gated computed tomography angiography (CCTA). Methods: A total of 350 consecutive patients without known cardiac diseases or significant (>50%) stenosis undergoing CCTA between January 2009 and June 2014 for suspected coronary artery disease were included. Cardiac chamber volumes adjusted to BSA were calculated using automated model-based segmentation analysis software of the CCTA data and correlated with patients' mean heart rate during the scan. Results: There were 240 men and 110 women, median interquartile range age was 55 years (47–61). Women were older 59.0 years (53.7–64) versus 52.0 years (45.0–59.0), had higher prevalence of hyperlipidemia, diabetes mellitus, anemia, and hypothyroidism, and higher median heart rates 64.0 (59.7–66.0) versus 60.0 (55.0–65.0) (p < 0.001). Men had a negative correlation between the volume of each cardiac chamber and the heart rate [rage_adj = (−0.4)–(−0.27), p < 0.001 for all], whereas such a correlation was not found in women. The multivariate analysis showed that a decrease of five beats per minute was associated with an increase of 4%–5% in volume of each chamber in men. There was no such association among females. Conclusions: Lower heart rate is associated with an increase of each cardiac chamber volume by CCTA in men. This association is not found in women. More extensive studies are required to further elaborate on these gender differences.
Does GPER1 Play a Role in Sexual Dimorphism?

Estrogens are critical in driving sex-typical social behaviours that are ethologically relevant in mammals. This is due to both production of local estrogens and signaling by these ligands, particularly in an interconnected set of nuclei called the social behavioural network (SBN). The SBN is a sexually dimorphic network studied predominantly in rodents that is thought to underlie the display of social behaviour in mammals. Signalling by the predominant endogenous estrogen, 17β-estradiol, can be either via the classical genomic or non-classical rapid pathway. In the classical genomic pathway, 17β-estradiol binds the intracellular estrogen receptors (ER) α and β which act as ligand-dependent transcription factors to regulate transcription. In the non-genomic pathway, 17β-estradiol binds a putative plasma membrane ER (mER) such as GPR30/GPER1 to rapidly signal via kinases or calcium flux. Though GPER1’s role in sexual dimorphism has been explored to a greater extent in cardiovascular physiology, less is known about its role in the brain. In the last decade, activation of GPER1 has been shown to be important for lordosis and social cognition in females. In this review we will focus on several mechanisms that may contribute to sexually dimorphic behaviors including the colocalization of these estrogen receptors in the SBN, interplay between the signaling pathways activated by these different estrogen receptors, and the role of these receptors in development and the maintenance of the SBN, all of which remain underexplored.
Change Rippling through Our Waters and Culture

This is the peer reviewed version of the following article: [Change Rippling through Our Waters and Culture. Journal of Contemporary Water Research & Education 169, 1 p61-78 (2020)], which has been published in final form at https://doi.org/10.1111/j.1936-704X.2020. 03332.x. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions: rippling Abstract: It is well established that climate change is already causing a wide variety of human health impacts in the United States and globally, and that for many reasons Native Americans are particularly vulnerable. Tribal water security is particularly threatened; the ways in which climate changes are damaging community health and well-being through impacts on water resources have been addressed more thoroughly for Tribes in coastal, arid, and sub-arctic/arctic regions of the United States. In this article, Crow Tribal members from the Northern Plains describe the impacts of climate and environmental change on local water resources and ecosystems, and thereby on Tribal community health and well-being. Formal, qualitative research methodology was employed drawing on interviews with 26 Crow Tribal Elders. Multiple determinants of health are addressed, including cultural, social, economic, and environmental factors. The sense of environmental-cultural-health loss and despair at the inability to address the root causes of climate change are widespread. Yet the co-authors and many other Tribal members are actively prioritizing, addressing, and coping with some of the local impacts of these changes, and are carrying on Apsáalooke [Crow] lifeways and values. we
Enclave Computing on RISC-V: A Brighter Future for Security?

The large attack surface of commodity operating systems motivated academia and industry to develop novel security architectures which provide strong protection for sensitive applications in so-called enclaves that only require trust in the hardware and minimal software components. However, the enclave architectures proposed by industry often lack important features, such as secure I/O, and assume threat models which leave out important classes of attacks, such as microarchitectural attacks. Thus, recent works in academia have proposed a new line of enclave architectures with distinct features and more comprehensive threat models, many of which were developed on the open RISC-V architecture. In this paper, we present a brief overview of the RISC-V based enclave architectures proposed in academia, discuss their features, limitations and open challenges which we tackle in our current research.
Imputation accuracy of whole-genome sequence in pigs

In the current study we evaluated imputation accuracy for Sus scrofa autosome 7 (SSC7) for imputation from a 70k SNP chip to whole-genome sequence (WGS), from a 660k SNP chip to WGS, and a two-step procedure from 70k to 660k to WGS, using Beagle 4.1, Minimac3 and FImpute. A reference population of 168 pigs with WGS data from several European breeds and lines was used to do a leave-one-out cross-validation. Results showed that imputation from 660k is more accurate compared to imputation from 70k directly to WGS. The two-step procedure from 70k to 660k to WGS showed the lowest imputation accuracy due to relatively poor imputation accuracy in the first step due to the limited reference population. Minimac3 seemed to perform best, but with a closer look at the details, Beagle 4.1 outperformed Minimac3. FImpute performed less well, but was not used to its full potential here as pedigree information was not included in the imputation. Imputation from commercial SNP chips to WGS in pigs is possible, in practise with even better results than shown here, however imputation accuracy is limited by the size of the current reference population at hand.
Social Media Cyberbullying: Awareness and Prevention through Anti Cyberbully Interactive Video (ACIV)

The development of ACIV is carried out to increase youth awareness about cyber bullying. Yet, the development of ACIV not just beneficial for youth, also to be good for the society which help to decrease the number of criminal cases such as vandalism, violence and several tragedies such as murder cases and committing suicide. In this project, the development of interactive video about anti cyberbully will be carried out to help youth to increase their awareness of cyberbullying and the way to prevent and tackle cyberbullying cases. Previous cyberbullying cases which lead to committing suicide will be imitated in Anti Cyberbully Interactive Video (ACIV). Therefore, this study aims to develop the interactive video about anti cyberbullying (ACIV).
Polymorphism Candidate Genes of Indigenous Lien Minh Chickens

Lien Minh chicken is an indigenous breed with several favorable properties, such as high productivity and good meat quality, and is associated with the economic development of the people in the Lien Minh village, Cat Hai, Hai Phong. The objective of the current research was to investigate the single nucleotide polymorphisms (SNPs) of candidate genes, which might be associated with broodiness and egg production traits. Ninety Lien Minh chicken individuals were genotyped for five SNPs of chicken prolactin (PRL), Vasoactive Intestinal Peptide (VIP), neuropeptide Y gene (NPY), growth hormone (GH), and growth hormone receptor (GHR) genes. Blood samples were used for DNA extraction and then for genotyping by the PCR-RFLP method. The allele frequencies obtained were as follows: 0.19 and 0.81 for alleles C and T (PRL-C2161G), respectively; in VIP (G5138982T), 0.55 for the G allele and 0.45 for T; in GH-SacI (the intron 4), 0.02 for A and 0.98 for B; and in GHR-NspI, 0.82 for C and 0.18 for T. The NPY gene (four nucleotide indel) had the frequencies of 0.86 for I and 0.14 for D. The four studied polymorphic loci (PRL, VIP, NPY, and GH) were in Hardy-Weinberg equilibrium in the Lien Minh chicken population. These are the initial results, which can be used to analyze the correlation of molecular markers and egg production traits in Lien Minh chickens.
Comparative postharvest responses of carnation and chrysanthemum to synthesized silver nanoparticles (AgNPs)

Carnation (Dianthus caryophyllus L.) and chrysanthemum [Dendranthema grandiflorum (Ramat.) Kitam. ] cut flowers are among the most important commodities that dominate flower markets throughout the world. Two major problems in the transportation and marketing of these flowers are their relatively short vase life and the rapid decline of their aesthetic value. In this respect, the current study investigates the effects of silver nanoparticles (AgNPs) on ethylene-sensitive (carnation) and ethylene-insensitive (chrysanthemum) cut flowers. Specifically, this research examines their morpho-physicochemical characteristics, antioxidant enzyme activities and vase life. Here, the AgNPs were synthesized by chemical methods and then applied on both flowers by a pulsing method. The treatments involved two concentrations of AgNPs (0.04 and 0.08gL-1) along with the control (deionized water), and the duration of exposure lasted for 24 h. Then, the flower stems were placed in an aqueous sucrose solution (4%) until the end of the experiment. All traits, except the vase life, were evaluated after 0, 3, 6 and 9 d following the treatments during the vase period. During this time, the control groups of both flowers showed considerable amounts of decrease in the relative fresh weight (RFW), vase solution uptake (VSU), flower diameter, membrane stability index (MSI) and total soluble carbohydrate (TSC). Meanwhile, there were increases in hydrogen peroxide content (H2O2) and peroxidase (POD) activity. The bacterial population of the stem end and total soluble protein (TSP) increased in carnation petals, but decreased in chrysanthemum petals. The activity of superoxide dismutase (SOD) dropped in carnation petals, whereas it rose in chrysanthemum petals. Using AgNPs at concentrations of 0.08 and 0.04gL-1 can optimally extend the vase life of carnation and chrysanthemum, respectively.
Mobile Apps in Tourism Communication: The Strengths and Weaknesses on Tourism Trips

The IR4.0 wave has fostered the variety of development of mobile apps inclusive of apps that are useful to ensure the smoothness of tourism activities. These mobile apps have replaced many of the functions of tourism workers in the tourism industry. However, the question is to what extent both the effectiveness and weaknesses of these apps can help and satisfy a tourist during his tour visit. Therefore, this concept paper will discuss the strengths and weaknesses of using mobile apps to serve the purpose of smoothening the tour visit and tourism communications. The writing of this paper is based on research focusing on the use of mobile apps in tourism from 2011 to date. the findings of the study indicate that the application of mobile apps in tourism communication isn’t replacing the function of human workers in the tourism sector entirely. Although there are some strengths in using the mobile apps, on the other, it still has much weakness which requires improvements to be made to meet tourist’s needs. Thus, this study will further illustrate the level of effectiveness of using mobile apps in the tourism industry as a source of reference to the mobile apps developer who created the sophisticated apps and fulfills the demand of tourists. This also will further become a reference to LR in improvising the quality of the service of a tourist destination.
The Benefit of Purple Aruk Rice (Siangu) in Lowering Body Mass Index (BMI) and Body Fat Percentage

Aruk rice is an iconic rice from Province of Bangka Belitung which is made from cassava while purple aruk rice (PAR)e is made from sweet potato ( Ipomea batatas ). Ipomea batatas is a high nutritional food that possesses several medicinal value including anti-cancer, antidiabetic, and anti-inflammatory activities. This research aimed to assest the organoleptic features of PAR and analyze the effect of PAR consumption in lowering the BMI and bofody fat percentage. The design of this research was randomized crossover design with quasi experimental research within subjects single-factor two-level design. This experiment consist of three phases, phase 1 (plain rice consumption), wash out phase, and phase 3 (PAR consumption). The only different between two phases was the source of the carbohydrate. The data of decreasing BMI and body fat percentage betweern plain rice diet and purple aruk rice was analyzed by using paired t test. Organoleptic assessment showed that the aroma of PAR is dislikeable but the natural purple colour is likeable. The decreasing of BMI and body fat percentage was found higher in phase 2 (2,05±0,10) than phase 1 (0,4±0,14), p=0,002. The decreasing of body fat percentage was also found higher in phase 2 or purple aruk rice diet (2,55±0,25) compared to phase 1 plain rice diet (0,5±0,20), p=0,003. Consumption of aruk purple rice lower BMI and body fat percentage more effective than consumption of plain rice.
Bayesian demand model based seismic vulnerability assessment of a concrete girder bridge

In the present study, by employing fragility analysis, the seismic vulnerability of a concrete girder bridge, one of the most common existing structural bridge systems, has been performed. To this end, drift demand model as a fundamental ingredient of any probabilistic decision-making analyses is initially developed in terms of the two most common intensity measures, i.e., PGA and Sa (T1). Developing a probabilistic demand model requires a reliable database that is established in this paper by performing incremental dynamic analysis (IDA) under a set of 20 ground motion records. Next, by employing Bayesian statistical inference drift demand models are developed based on pre-collapse data obtained from IDA. Then, the accuracy and reasonability of the developed models are investigated by plotting diagnosis graphs. This graphical analysis demonstrates probabilistic demand model developed in terms of PGA is more reliable. Afterward, fragility curves according to PGA based-demand model are developed.
Serum based polymerase chain reaction and enzyme linked immunosorbent assays for diagnosis of bovine brucellosis

Brucellosis is one of the economically important diseases in India and diagnosis of brucellosis using single test is cumbersome due to variation in sensitivity and specificity among the different test. The present study was aimed to assess the suitability of serum as clinical specimen in molecular diagnosis and evaluate the serology and molecular assays as in diagnosis of bovine brucellosis. A total of 821 bovine sera samples were subjected to indirect Enzyme Linked Immunosorbent Assay (i-ELISA) and serum based Polymerase Chain Reaction (PCR) assay. On serology 6.70 per cent positivity of brucellosis were reported and on PCR assay, 47 and 29 sera samples were positive for bcsp 31 genus specific and IS711 species specific PCR assay respectively with per cent positivity of 5.72 and 3.53. In comparison between serology and molecular test, 44 samples were positive for both assays and 11 and 3 samples were positive for serology and molecular assays individually. This study suggests that serum sample can be utilised as the choice of clinical specimen for both PCR assay and i-ELISA will be a future choice for the diagnosis of bovine brucellosis.
CHANGES IN CARBOHYDRATE CONTENTS IN TABLE POTATO TUBERS UNDER THE INFLUENCE OF SOIL CONDITIONER UGMAX

The content of total sugars and reducing sugars in potato tubers is one of the most important quality features determining the suitability for direct consumption and for processing into food products. The objective of the study was to determine the effect of the soil conditioner UGmax on total sugars, reducing (simple) sugars and sucrose in potato tubers. Experimental material consisted of tubers of second early table potato grown in a field experiment conducted in central-eastern Poland. Following chemical analyses, statistical calculations were performed and they demonstrated a significant effect − an application of the soil conditioner UGmax contributed to an increase in the tuber content of reducing sugars compared with control potato tubers. The highest simple sugar content was found after three applications of the soil conditioner at the rate of 1.0 and 2.0 dm ha. The remaining carbohydrates determined in the study did not respond to UGmax application. Cultivars grown in the study differed significantly in terms of reducing sugar content only, more sugars being accumulated by Tajfun rather than Satina.
Draft Genome Sequences of Cronobacter muytjensii Cr150, Cronobacter turicensis Cr170, and Cronobacter sakazakii Cr611

The sequencing and bioinformatics analyses of isolates Cr150, Cr170, and Cr611 from powdered infant formula indicate that the three strains represent new members in the Cronobacter muytjensii, Cronobacter turicensis, and Cronobacter sakazakii groups, respectively. ABSTRACT The sequencing and bioinformatics analyses of isolates Cr150, Cr170, and Cr611 from powdered infant formula indicate that the three strains represent new members in the Cronobacter muytjensii, Cronobacter turicensis, and Cronobacter sakazakii groups, respectively.
POTENTIAL MARINE-DERIVED FUNGI ISOLATED FROM SPONGE IN PRODUCE NEW AND BENEFICIAL COMPOUNDS

Marine organisms are a source of natural products and produce compounds with a molecular structure that is unique and useful. Thousands of new compounds have biological activitity for anticancer, antiviral, and antimicrobial. This compounds isolated from various marine organism, including from marine-derived fungi. Investigation of chemical compounds from marine-derived fungi isolated from sponge has increased steadily, indicating the important role of marine-derived fungi in the discovery of drug compounds. The sponge has produced various kinds of fungi, which have reported to provide a variety of pharmacologically active metabolites and structurally diverse. Study literature showed that many fungal genera isolated from the marine sponge dominated the genus Acremonium, Aspergillus, Penicillium, Phoma, and Fusarium. The high proportion of genera and new compounds showed that the fungi isolated from the sponge could develop.
Recent Advances in Big Data: Features, Classification, Analytics, Research Challenges, and Future Trends

Dealing with big data at present involves several procedures, including storage, processing, indexing, integration, and governance; thus, it poses a major challenge to application developers and research scientists. The challenge increases when accurate results must be obtained for queries in decision-making and cognitive applications regarding various disciplines and industries. A variety of literature on big data is available. However, big data must still be understood through various aspects, such as features, classification, analytics, research challenges, and future trends. This study provides a deep understanding of big data features, classification, and manipulation. An improved understanding of big data analytics and recent research challenges is also provided. Additionally, future trends are discussed for researchers. In conclusion, a vision to wisely and accurately improve information retrieval or search is presented to make better decisions using big data.
Forecasting Trajectories of Fabricated and Natural Capital: A Political Economic Model of Doomsday, Social-ecological Resilience and Green Innovation

An instructive graphical macroeconomic theory is recapitulated describing the interaction of private production of commercial services with natural production of ecosystem services. It features investments in maintaining the health of natural capital and analysis of marginal changes in absolute metrics of private and natural capital productivity. Analysis of trade-offs among costs, benefits and wealth production explore macroeconomic trajectories employing sustained yield doctrine, lowimpact technologies, green technologies, artificial production of ecosystem services, debt-financed natural capital investments and a more probable scenario. Sustained yield won’t work as a policy or prescriptive framework. Widespread restoration of robust ecosystems is unlikely, but resilient natural capital systems may be possible. Large investments in natural capital restoration and low-impact green technologies are required while retaining reasonable levels of profitability in both the commercial and ecosystem restoration sectors. The role of projected innovation in achieving long-term sustainability and climate stability is projected and unresolved issues identified.
Tbx1 and Foxi3 genetically interact in the third pharyngeal pouch endoderm required for thymus and parathyroid development

The mechanisms required for segmentation of the pharyngeal apparatus to individual arches are not precisely delineated in mammalian species. Here, using conditional mutagenesis, we found that two transcription factor genes, Tbx1, the gene for 22q11.2 deletion syndrome and Foxi3, genetically interact in the third pharyngeal pouch endoderm for thymus and parathyroid gland development. We found that Tbx1 is autonomously required for the endoderm to form a temporary multilayered epithelium while invaginating. E-cadherin for adherens junctions remains expressed and cells in the apical boundary express ZO-1. Foxi3 is required autonomously to modulate proliferation and promote later restoration of the endoderm to a monolayer once the epithelia meet after invagination. Completion of this process cooccurs with expression of Alcam needed to stabilize adherens junctions and extracellular, Fibronectin. These processes are required in the third pharyngeal pouch to form the thymus and parathyroid glands, disrupted in 22q11.2 deletion syndrome patients.
Incremental Network Configuration Verification

Network configurations are constantly changing, and each change poses a risk of catastrophic network outages. Consequently, the networking community has put significant effort into developing and optimizing configuration verifiers. However, we observe existing configuration verifiers still have a significant drawback: they are not optimized for configuration changes. That is, they always check a snapshot of network configuration from scratch, even though the configuration often changes slightly since the last verification. In this paper, we demonstrate the benefits, opportunities, and challenges of incremental network configuration verification (INCV). We also demonstrate the feasibility of INCV by introducing RealConfig, an incremental configuration verifier that can check configuration changes within one second.