Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploring the Relationship Between Momentary Emotions & Smartphone Content: A Pilot Study

Using a novel dataset of 28,905 screenshots of actual smartphone activity, we explored the relationship between momentary emotions and on-screen, smartphone content as seen and produced by participants in the wild. 13 participants installed the Stanford Screenomics application (a custom-built smartphone app that continually collects screenshots of smartphone activity) and completed experience sampling reports of their momentary emotions up to five times per day during a two-week study. We examined smartphone content by analyzing the on-screen text that participants both passively consumed and actively produced. Using the Linguistic Inquiry and Word Count (LIWC) program to perform text analyses, we found that smartphone content (e.g., on-screen text with higher amounts of cognitive or emotional words) was associated with momentary emotional experience (e.g., annoyance, boredom, and sadness). While these findings must be replicated in a larger study, they indicate that studying actual smartphone content can reveal new insights into the relationships between people’s emotional experiences and their digital activity. We suggest that future research may eventually use passively collected smartphone content in order to create personalized models that predict
Analysis on Possibility of Terrapin Invasion and Its Countermeasures

The conditions of the terrapin market and breeding areas are explored in the paper.Based on an analysis on the trend of the development in the terrapin market,it discusses the possible reasons of the terrapin invasion,as well as the potential risk that the alien terrapin might give the ecosystem in China.In order to drive the attention of the relative departments,the article gives its suggestion to help prevent the invasion.
Significance of Thyroid Peroxidase Antibodies in Cases of Recurrent Pregnancy Loss in Patients who are Euthyroid-A Short Communication

Recurrent pregnancy loss (RPL) is really a depressing problem. Random chromosomal alterations numerically like trisomy, monosomy, as w ell as polyploidy are the commonest reasons of miscarriage during the 1st 10 weeks of gestation age (GA), that literally are responsible for 50% of cases [1]. Following exclusion of these explained miscarriages, RPL correlates with endocrinopathies, immunological, anatomical as well as inherited genetic causes [2].
Miura-Reciprocal transformations for two integrable hierarchies in 1 + 1 dimensions

We here present two different hierarchies of PDEs in 1+1 dimensions whose first and second member are the shallow water wave Camassa-Holm and Qiao equations, correspondingly. These two hierarchies can be transformed by reciprocal methods into the Calogero-Bogoyanlevski-Schiff equation (CBS) and its modified version (mCBS), respectively. Considering that there exists a Miura transformation between the CBS and mCBS, we shall obtain a relation between the initial hierarchies by means of a composition of a Miura and reciprocal transforms.
Evidence for superconductivity in Li-decorated monolayer graphene

Monolayer graphene exhibits many spectacular electronic properties, with superconductivity being arguably the most notable exception. It was theoretically proposed that superconductivity might be induced by enhancing the electron–phonon coupling through the decoration of graphene with an alkali adatom superlattice [Profeta G, Calandra M, Mauri F (2012) Nat Phys 8(2):131–134]. Although experiments have shown an adatom-induced enhancement of the electron–phonon coupling, superconductivity has never been observed. Using angle-resolved photoemission spectroscopy (ARPES), we show that lithium deposited on graphene at low temperature strongly modifies the phonon density of states, leading to an enhancement of the electron–phonon coupling of up to λ≃ 0.58. On part of the graphene-derived π*-band Fermi surface, we then observe the opening of a Δ≃ 0.9-meV temperature-dependent pairing gap. This result suggests for the first time, to our knowledge, that Li-decorated monolayer graphene is indeed superconducting, with Tc ≃5.9 K.
Generation of dark pulses in a bismuth tellurite based mode-locked erbium-doped fiber laser

We report on the formation of dark pulses in a highly nonlinear fiber laser passively mode-locked by a Bistmuth Tellurite (Bi2Te3) based SA. The SA was fabricated by embedding Bi2Te3 powder into polyvinyl alcohol (PVA) film by a solution casting technique. By inserting the SA into an EDFL cavity, stable mode-locked operation was achieved at 1592.68 nm with the maximum pulse energy up to 2.38 nJ by adjusting polarization controller. The laser operated at pulse repetition frequency of 1.0 MHz with a pulse width of 215 ns. These results suggested that Bi2Te3 could be developed as an effective SA for mode-locked dark pulses generation in a highly nonlinear cavity.
Effective Measurement of Website Engagement to Improve Website Content

User engagement, which has been addressed as the emotional, cognitive and behavioral connection that exists between a user and a resource, is the result of trustworthy, quality, relevant and interesting content. In this paper, we evaluate one type of engagement, “stickiness” also referred to as site engagement, which is concerned about users “spending time” on a site. Certainly, the success of a site largely depends on itself, but also on how it is connected on the web and how web traffic arrives to it. This is particularly important for large online providers, such as AOL, MSN and Yahoo! , which offer a variety of content sites (e.g. news, sport, e-commerce) Social network sites (SNSs) are increasingly attracting the attention of academic and industry researchers intrigued by their affordances and reach. In the vein of other terms related to online sytem in which persons are deliberately capable of constructing an online image of self for example Matrimonial sites, online dating sites are compose of an key research framework for people investigating processes of friendship performance, self-presentation and impression management. While interacting online with people is now a day’s very common and effective way of enhancing the worth of websites used for business purposes. And due to these consequences, it becomes important for web site designers to understand the concept and its impact on the quality of website design.
Toxicity evaluation of encapsulated and non- encapsulated Astaxanthin in Swiss albinos mice

Astaxanthin is a keto carotenoid found in many crustaceans and microorganism especially in Haematococcus pluvialis. Astaxanthin was encapsulated with liposomal substances. The objective of the study was to investigate the acute and sub-acute toxicity of encapsulated and non-encapsulated astaxanthin. The test samples in the range of 250, 500 and 1000 mg/g bw was taken. Each group consists of 5 animals. No deaths occurred and no treatment-related changes were observed in the detailed clinical observations, manipulative tests, hematology, blood chemistry, organ weight, but some changes like grip strength, motor activity, body weights, food consumption and histopathology was founded. Body color changes were also found in higher dose of both encapsulated and non-encapsulated astaxanthin. Based on this results, it was concluded that the 250 mg/kg bw has no side effect when compared to 500 and 1000 mg/kg bw in acute toxicity study. Further, in sub-acute toxicity all the dose like 20, 40 and 80 mg/kg bw shows no adverse effect. Hence, the dosage for anticancer study can be fixed at 20 mg/kg bw respectively.
Altered energy partitioning across terrestrial ecosystems in the European drought year 2018

Drought and heat events, such as the 2018 European drought, interact with the exchange of energy between the land surface and the atmosphere, potentially affecting albedo, sensible and latent heat fluxes, as well as CO2 exchange. Each of these quantities may aggravate or mitigate the drought, heat, their side effects on productivity, water scarcity and global warming. We used measurements of 56 eddy covariance sites across Europe to examine the response of fluxes to extreme drought prevailing most of the year 2018 and how the response differed across various ecosystem types (forests, grasslands, croplands and peatlands). Each component of the surface radiation and energy balance observed in 2018 was compared to available data per site during a reference period 2004–2017. Based on anomalies in precipitation and reference evapotranspiration, we classified 46 sites as drought affected. These received on average 9% more solar radiation and released 32% more sensible heat to the atmosphere compared to the mean of the reference period. In general, drought decreased net CO2 uptake by 17.8%, but did not significantly change net evapotranspiration. The response of these fluxes differed characteristically between ecosystems; in particular, the general increase in the evaporative index was strongest in peatlands and weakest in croplands. This article is part of the theme issue ‘Impacts of the 2018 severe drought and heatwave in Europe: from site to continental scale’.
Breaking dormancy in Arbutus andrachne L. seeds by stratification and gibberellic acid

To break dormancy and allow germination of Arbutus andrachne L. (Eastern Strawberry tree) seeds, various methods were tested including scarification with hot water, sulphuric acid (H 2 SO 4 ), or potassium hydroxide (KOH), cold moist stratification and treatment of seeds with potassium nitrate (KNO 3 ), thiourea, or gibberellic acid (GA 3 ). None of the seeds in the control or those scarified with H 2 SO 2 or KOH, or treated with KNO 3 or thiourea germinated. Hot water scarification allowed some germination, the greatest being 36% when seeds were soaked in water at 60°C for three minutes. Stratification of seeds at 4°C for three to four months or treatment of seeds with 250 mg/liter GA, was successful as 86% of the seeds germinated for both treatments.
Diverse outcomes of controlled human malaria infection originate from host-intrinsic immune variation and not var gene switching

Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, asking whether this relationship underpins the variation observed in controlled human malaria infection (CHMI). We uncovered marked heterogeneity in the response of naive hosts to blood challenge; some volunteers remained quiescent, others triggered interferon-stimulated inflammation and some showed transcriptional evidence of myeloid cell suppression. Significantly, only inflammatory volunteers experienced hallmark symptoms of malaria. When we tracked temporal changes in parasite VSA expression to ask whether variants associated with severe disease preferentially expand in naive hosts (as predicted by current theory) we found that var gene profiles were unchanged after 10-days of infection. The diverse outcomes of CHMI therefore depend upon human immune variation and there is no evidence for switching or selection of var genes in naive hosts.
A Background Noise Self-adaptive VAD Using SNR Prediction Based Precision Dynamic Reconfigurable Approximate Computing

This paper proposed a background-noise self-adaptive voice activity detection (VAD) accelerator using SNR prediction based precision dynamic reconfigurable approximate computing. To improve the energy efficiency while maintaining high recognition accuracy for different background noises, two optimization techniques are proposed. Firstly, we proposed a SNR prediction module to analyze and pre-classify the back-ground noise into different levels, and a binarized weight network (BWN) accelerator with reconfigurable data bit width to implement the feature classification of VAD. Then, we proposed an approximate computing architecture with precision self-adaptive approximate addition unit to further reduce the energy consumption of BWN accelerator. Evaluated under 28nm process technology, this work can achieve high recognition accuracy (speech/none-speech hit rate: 95%/92% @10dB, 90%/87% @5dB, and 85%/80% @-5dB) under different background noise (SNR-5dB) with a low power consumption of 2 ~ 8uW.
The emotional trade-off between meaningful and precarious work in new economies

The contradictory work environments of new economies in late modernity are associated with a range of emotional experiences, requiring diverse emotion management strategies. Late modernity offers the capacity to pursue happy, safe, rewarding, and meaningful work for the privileged few; a potential trade-off between stressful meaningful and boring precarious work for a greater number; and the prospect of non-meaningful, precarious work for many in the new economy characterised by short-term contracts, gig work, precarity, and anxiety. This study draws on data from the 2015–16 Australian Social Attitudes Survey to examine workers’ emotions in various combinations of meaningful and precarious employment, and the degree to which these emotions are managed. It finds that it is best to have secure meaningful work, worst to have highly precarious work, and slightly better to have safe but alienating than risky meaningful work, in terms of avoiding often hidden negative emotions.
Comparison of xMAP Salmonella Serotyping Assay With Traditional Serotyping and Discordance Resolution by Whole Genome Sequencing

Salmonella spp. are a major cause of foodborne illness throughout the world. Traditional serotyping by antisera agglutination has been used as a standard identification method for many years but newer nucleic acid-based tests have become available that may provide advantages in workflow and test turnaround time. In this study, we evaluated the Luminex® xMAP® Salmonella Serotyping Assay (SSA), a multiplex nucleic acid test capable of identifying 85% of the most common Salmonella serotypes, in comparison to the traditional serum agglutination test (SAT) on 4 standard strains and 255 isolates from human (224), environmental, and food (31) samples. Of the total of 259 isolates, 256 could be typed by the SSA. Of these, 197 (77.0%) were fully typed and 59 (23.0%) were partially typed. By SAT, 246 of the 259 isolates (95%) were successfully typed. Sixty isolates had discrepant results between SAT and SSA and were resolved using whole genome sequencing (WGS). By SAT, 80.0% (48/60) of the isolates were consistent with WGS while by SSA 91.7% (55/60) were partially consistent with WGS. By serovar, all 30 serovars except one tested were fully or partially typable. The workflow comparison showed that SSA provided advantages over SAT with a hands-on time (HOT) of 3.5 min and total turnaround time (TAT) of 6 h, as compared to 1 h HOT and 2–6 days TAT for SAT. Overall, this study showed that molecular serotyping is promising as a rapid method for Salmonella serotyping with good accuracy for typing most common Salmonella serovars circulating in China.
STUDIES ON NATURAL POPULATIONS OF DROSOPHILA. III. MORPHOLOGICAL AND GENETIC DIFFERENCES OF WING LENGTH IN DROSOPHILA MELANOGASTER AND D. SIMULANS IN RELATION TO SEASON

Two main experiments were carried out each month of the experimental period to study the morphological and genetical differences in the various populations of Drosophila melanogaster and D. simulans. 1. Morphological dijjerences. -Progeny resulting from the F2 generation of the captured females in both species and those of the laboratory populations were used for collecting eggs to study the monthly morphological differences among various poputhe basis of the present study; each species consists of: 1. Natural populations. -Natural populations from each of the two species captured at the Alexandria University Farm were used. Collections of flies were made once every 15 days from October, 1961 to December, 1962. For locality, methods of collection, identification of both species, and technique used for the maintenance of such populations, see Tantawy and Mallah (1961). 2. Laboratory populations. -Populations of the same two species captured in the same region 5 years prior to the experimental work were used. Populations of both species were kept by mass mating in breeding bottles at 25° C under two different environmental conditions: a. Optimal conditions, i.e., not more than 200 eggs from the mass mating population cultured in a well-yeasted bottle. b. Severe conditions of crowding, i.e., 50 pairs of flies per bottle were left to lay eggs freely in food bottles which were poorly yeasted. These laboratory populations are called "optimal" and "severe" populations, respectively.
Microbial DNA extraction from samples of varied origin

The impact of four different soil DNA extraction methods on the quantity and quality of isolated community DNA was evaluated using agarose gel electrophoresis, DNA spectrum study and PCR-based 16S ribosomal DNA analysis. The modified direct lysis method was optimized for environmental water samples (wastewater fed-fisheries and raw liquid sewage canal) as well as diagnostic samples like urine from humans, thus opening up a new arena for fast culture-independent detection of causative pathogens in pathological manifestations like urinary tract infections. The same method was independently found to be effective for isolation of genomic DNA from both Gram-positive and Gram-negative bacteria. Thus a uniform method of DNA extraction from environmental samples (different types of soil and water), pathological samples as well as varied kinds of bacteria was obtained.
Pushing The Boundaries of Bioluminescence Using Synthetic Luciferins: A Dissertation

Fireflies are beetles that generate yellow-green light when their luciferase enzyme activates and oxidizes its substrate, D-luciferin. This bioluminescent reaction is widely used as a sensitive reporter both in vitro and in vivo. However, the light-emitting chemistry is limited by the properties of the small molecule Dluciferin. Our lab has developed a panel of synthetic luciferin analogs that improve on the inherent characteristics of D-luciferin. My thesis work focuses on harnessing these novel substrates to further expand the utility and molecular understanding of firefly bioluminescence. The first part of my thesis focuses on using synthetic luciferins to improve bioluminescence imaging beyond what is possible with D-luciferin. Our substrates emit red-shifted light compared to D-luciferin, bringing the wavelength to a range that is more able to penetrate through tissue, but at a cost of lower signal intensity. I developed mutant luciferases that increase the maximal photon flux with the synthetic luciferins over what is achievable with the wild-type luciferase, and furthermore discriminate between substrates based on their chemical structures. Additionally, I have expanded the bioluminescence toolkit by harnessing the intrinsic properties of the luciferins to non-invasively and specifically assay the activity of a single enzyme (fatty acid amide hydrolase) in live mice. Therefore, my work presents an effective way to generally improve
Aquaporin‐2 and NKCC2 expression pattern in patients with hepatosplenic schistosomiasis

Schistosoma mansoni infection is considered a public health problem. Glomerular involvement in schistosomiasis is a well‐documented complication, especially in hepatosplenic schistosomiasis (HSS). However, renal tubular function is poorly understood. The aim of this study was to investigate, through urinary exosomes, tubular transporters functionally in HSS patients.
Conflicts Between Farmers and Conservationists: The Role of Communication in the Management of Natural Resources

Abstract The importance of communication in conflict situations between conservationists and farmers about problems related to agricultural practices such as erosion, biodiversity loss, and water quality has been highlighted frequently. However, in the Czech Republic, there is a very limited amount of scientific data about this issue. This article presents a literature review summarising evidence on how conflicts between farmers and environmentalists proceed; steps that can be taken to achieve progress in face-to-face communication and there is also a case study of a specific collaborative partnership from a small parish in South Moravia that focuses on improving natural values. Recommendations on how to build more constructive dialogue and develop cooperation between various groups are analysed, and principles that enhance dialogue and may contribute to overcoming disagreements through partnership are indicated. The collaborative partnership in the case study involves a farmer working together with a municipality and other stakeholders on a local level to improve nature conservation and ecosystem services. The majority of the general principles of collaboration and communication for conflict resolution that were identified in the literature review were fulfilled; nevertheless, the partnership currently has limited outreach as the two agribusiness companies which manage the majority of the land in the parish have not been included.
Predictive factors of progression to severe COVID-19

Abstract Aim Early diagnosis and treatment are crucial for the survival of severe Coronavirus Disease 2019 (COVID-19) patients, but data with regard to risk factors for disease progression from milder COVID-19 to severe COVID-19 remain scarce. Methods We conducted a retrospective analysis on 116 patients. Results Three factors were observed to be independently associated with progression to severe COVID-19 during 14 days after admission: (a) age 65 years or older (hazard ratio [HR] = 8.456; 95% CI: 2.706–26.426); (b) creatine kinase (CK) ≥ 180 U/L (HR = 3.667; 95% CI: 1.253–10.733); and (c) CD4+ T-cell counts <300 cells/µL (HR = 4.695; 95% CI: 1.483–14.856). The difference in rates of severe COVID-19 development was found to be statistically significant between patients aged 65 years or older (46.2%) and those younger than 65 years (90.2%), between patients with CK ≥ 180 U/L (55.6%) and those with CK < 180 U/L (91.5%), and between patients with CD4+ T-cell counts <300 cells/µL (53.8%) and those with CD4+ cell counts ≥300 cells/µL (83.2%). Conclusions Age ≥ 65 years, CK ≥ 180 U/L, and CD4+ T-cell counts <300 cells/µL at admission were risk factors independently associated with disease progression to severe COVID-19 during 14 days after admission and are therefore potential markers for disease progression in patients with milder COVID-19.
Discovery of TH-302: An achiral hypoxia-activated cytotoxic prodrug

3515 Background: Selective targeting of the hypoxic compartment of the tumor microenvironment is both a challenge and an opportunity for discovering and developing new cancer therapeutics. Chronic and transient hypoxia underlie resistance to chemotherapeutics and radiation. We have taken a modular design approach to synthesize hypoxia-activated prodrugs. Different nitro-containing heterocyclic triggers were linked to bis alkylating phosphorous mustard toxins and profiled in in vitro and in vivo assays predictive of compound efficacy and pharmacokinetics (PK). Methods: Drug candidates were synthesized and characterized using standard synthetic methods. In vitro efficacy was assessed with cancer cell line cytotoxicity and clonogenic assays. In vivo efficacy was assessed with xenograft models in monotherapy and combination therapy modes. Results: Screening trigger-toxin combinations in H460 lung cancer cell proliferation assays under anoxic, hypoxic, and aerobic conditions yielded structure-activity relation.