Miracle-dz/UniFAR-FTUs huggingface dataset:
PEARL: Peer-to-peer Effective Audio, Radio, and Light Communications

In recent years there has been an explosion of research in wireless communications, and our everyday lives and devices are moving more and more towards being untethered. This trend suggests that our devices will increasingly rely on wireless communication technologies to communicate; however, each technology offers its own unique set of trade-offs (e.g., low-power, short/long range, variable data rates) which make it an appealing method for communication for specific contexts, but not beyond those contexts. To further exacerbate the issue, some classes of devices may have certain constraints (e.g., limited power, security/privacy requirements, operating distance requirements) which limit the communicative capabilities of the device itself. What we believe is needed is a more capable communication framework and system that can (1) enable our devices to communicate with (nearby) devices by determining which communication channels are most effective given contextual information (e.g., about the environment, channel quality), and then (2) continuously adapt to use the communication channel(s) which yield the “best” and most reliable connection. In this paper, we propose a proof-of-concept implementation and evaluation of PEARL: a first of its kind communication system that enables Peer-to-peer Effective Audio, Radio, and visible Light communication capabilities that all co-exist on a single platform. PEARL, at its core, is meant to present an abstraction of the communication technologies implemented in the underlying system, enabling application and system developers to focus more on what data is communicated, while delegating the responsibility of figuring out how to best communicate with other devices to the system itself. Keywords—Audio, Amazing, Visible Light Communications, Awesome, Radio, Spectacular.
Efficient Approximate Visibility of Point Sets on the GPU

In recent years, considerable research has been devoted to the efficient representation, modeling, processing and rendering of point-based models (point clouds). Due to their conceptual simplicity and superior flexibility, point-based representations evolved into a valuable alternative to polygonal meshes. This paper explores the problem of extracting direct visibility from point clouds without explicitly reconstructing the surface or estimating normal. The main contribution of this work is a hardware-accelerated hidden point removal operator. This operator is based on the GPU splatting technique combined with a morphological operation over the depth buffer to reduce the silhouette effect in the final image. The motivation to develop a new operator is the low efficiency demonstrated by existing hidden point removal methods in real time applications with large point clouds. We demonstrate that our proposal is useful for visualizing point clouds with interactive frame rates.
Assay of yeast enzymes in situ. A potential tool in regulation studies.

A permeabilization method which allows the assay of several intracellular enzymes within the boundaries of the yeast cell wall is described. The kinetic properties of hexokinase and pyruvate kinase examined in the permeabilized cells, including the allosteric activation of the latter by fructose bisphosphate, are essentially the same as in cell-free extracts.
Registration of clinical trials still moving ahead--September 2008 update to Uniform Requirements for Manuscripts Submitted to Biomedical Journals.

The International Committee of Medical Journals' (ICMJE) policy on mandatory registration of clinical trials had made an important contribution to the transparency of clinical research even before it became a prerequisite for manuscript submission (1-3). Until recently, the scientific publication was the most detailed public record of the clinical trial, but reports in journals had been often burdened by selective reporting of trials and trial results, which very often distorted the evidence available for clinical decision-making (1).
The Stone Age of Palestine

The archaeology of Palestine, though far less spectacular than that of its neighbours, Egypt and Iraq, can always rely on a certain public outside the circle of specialists. Even the most uninspiring potsherds, if they are dug up in Jericho or Samaria, are invested with a certain glamour by their association with Joshua or Ahab, and the hope of unearthing the Ark of the Covenant or the tomb of David has inspired more than one forlorn venture. Until recent years, however, the Stone Age of Palestine, which receives no adventitious help from association with the Bible, has suffered from neglect. It is true that a considerable amount of surface material was collected, and the names of Pére Germer-Durand, Pére Vincent, Pére Mallon and Dr Paul Karge stand out as pioneers of prehistoric studies in this region, but until 1925 no systematic excavation had taken place. Ten years ago an article on the prehistory of Palestine would have been a very brief affair; today it is difficult to compress into a limited space all there is to say, so rich has this small country proved in the short time that excavation has been carried out.
Preferential Binding of Mouse Mammary Tumor Virus to B Lymphocytes

ABSTRACT Mouse mammary tumor virus (MMTV) has been shown to preferentially infect B lymphocytes in vivo. We have used recombinant envelope-coated fluospheres and highly purified MMTV particles to study the distribution of the viral receptors on fresh mouse lymphocytes. A preferential dose-dependent binding to B lymphocytes was observed which could be competed with neutralizing antibodies. In contrast, T-lymphocyte binding remained at background levels. These results strongly suggest a higher density of viral receptor molecules on B lymphocytes than on T lymphocytes and correlate with the preferential initial infection of B lymphocytes observed in vivo.
Periodical correlation analysis of digital data pulses for real-time medical applications

The main aim of the biomedical signal processing is to extract information from a biological signal. Biomedical signal processing involves recording of the biological events such as heart-beats etc. The feasibility of extracting accurate Heart-Rate is demonstrated by measuring the variability in the photoelectric plethysmography signals. The Pulse Rate is obtained from the systolic peaks of the pulse wave measured from a Heart-Beat sensor. From the Pulse Rate the Heart-Rate can be calculated. Digital Data Processing system involves real-time processing of Heart-Beat pulses. The captured data is processed in real time using Pulse Shape Discrimination Algorithm and verified on a field programmable gate array device. This study opens a way to derive heart rate from pulse rate with a simple assessment which can be applied to many persons suffering with various heart diseases. It is also analyzed the various distorted signals caused by motion artifacts are removed using morphological operators such as erosion and dilation without the help of any filters, and designed a PSD algorithm to calibrate the signals for better accuracy. The main focus is on the operation of Correlation with which the PSD has been designed. The proposed Algorithm is designed using Xilinx ISE 13.4.
Argument Relation Classiﬁcation Using a Joint Inference Model

In this paper, we address the problem of ar-gument relation classiﬁcation where argu-ment units are from different texts. We de-sign a joint inference method for the task by modeling argument relation classiﬁcation and stance classiﬁcation jointly. We show that our joint model improves the re-sults over several strong baselines
Reasoning Biases, Non-Monotonic Logics and Belief Revision

A range of formal models of human reasoning have been proposed in a number of fields such as philosophy, logic, artificial intelligence, computer science, psychology, cognitive science, etc.: various logics (epistemic logics; non-monotonic logics), probabilistic systems (most notably, but not exclusively, Bayesian probability theory), belief revision systems, neural networks, among others. Now, it seems reasonable to require that formal models of human reasoning be (minimally) empirically adequate if they are to be viewed as models of the phenomena in question. How are formal models of human reasoning typically put to empirical test? One way to do so is to isolate a number of key principles of the system, and design experiments to gauge the extent to which participants do or do not follow them in reasoning tasks. Another way is to take relevant existing results and check whether a particular formal model predicts these results. The present investigation provides an illustration of the second kind of empirical testing by comparing two formal models for reasoning – namely the non-monotonic logic known as preferential logic; and a particular version of belief revision theories, screened belief revision – against the reasoning phenomenon known as belief bias in the psychology of reasoning literature: human reasoners typically seek to maintain the beliefs they already hold, and conversely to reject contradicting incoming information. The conclusion of our analysis will be that screened belief revision is more empirically adequate with respect to belief bias than preferential logic and non-monotonic logics in general, as what participants seem to be doing is above all a form of belief management on the basis of background knowledge. The upshot is thus that, while it may offer valuable insights into the nature of human reasoning, preferential logic (and non-monotonic logics in general) is ultimately inadequate as a formal model of the phenomena in question.
Current Concepts in Antifungal Pharmacology SYMPOSIUM ON ANTIMICROBI

© 2011 Mayo Foundation for Medical Education and Research The era of systemic antifungal chemotherapy effectively began with the introduction of amphotericin B-deoxycholate in 1958 by Squibb Laboratories, after exhaustive attempts to develop orally bioavailable formulations of more than 200 polyene macrolide antibiotics produced by the soil actinomycete . Although amphotericin B was to become the criterion standard treatment for serious fungal infections for more than 40 years, infusion-related adverse effects and dose-limiting nephrotoxicity prompted the continued search for equally effective but less toxic alternatives that could be administered both intravenously and orally. This goal was not realized until more than 3 decades later with the introduction of fluconazole in 1990 (Figure 1). Unlike amphotericin B and the earlier imidazole antifungal agents (miconazole, ketoconazole), fluconazole possessed excellent oral bioavailability; predictable linear pharmacokinetics with wide distribution into many tissues, including the cerebral spinal fluid and vitreous chamber of the eye; and a much lower risk of drug interactions and toxicity in critically ill patients compared with earlier azoles. Fluconazole was also effective for the treatment of oropharyngeal candidiasis in patients with AIDS; however, resistance could be problematic in patients receiving prolonged treatment who had declining CD4 cell counts. Fluconazole Russell E. Lewis, PharmD
Gradient de prototypicalité lexicale : définition et cas d'application sur la terminologie des ontologies

Cet article presente une methode originale de calcul de prototypicalite lexicale, c'est-a-dire une mesure de difference de representativite des termes denotant un concept au sein d'une ontologie a partir d'un corpus de reference. Nous proposons deux champs d'applications de ce gradient : (1) l'analyse d'un corpus de textes, et (2) la determination a priori ou le controle a posteriori du choix des termes vedettes et des synonymes dans la terminologie des ontologies. Nous presentons egalement les resultats obtenus lors d'une experimentation menee a partir d'une ontologie des maladies rares (ONTOORPHA) et d'un corpus de textes composes des resumes des differentes entrees du portail des maladies rares ORPHANET, et confirmant l'interet de notre approche sur les deux champs d'application presentes.
Social and ethnic differences in folic acid use preconception and during early pregnancy in the UK: effect on maternal folate status.

BACKGROUND The role of folate supplementation in preventing neural tube defects is well known; however, preconception supplement use continues to be low, especially amongst the socially disadvantaged. The present study explored periconception folic acid supplement use in a socially deprived, ethnically diverse population. METHODS Pregnant women (n = 402) in the first trimester of pregnancy were recruited in East London. Using a researcher led questionnaire, details were obtained regarding social class, ethnicity and folic acid use. Red cell folate levels were determined for 367 participants during the first trimester. RESULTS Although 76% of participants reported using folic acid supplements during the first trimester, only 12% started preconception and a further 17% started before neural tube closure. Mothers from higher social groups or with higher levels of education were more likely to use folic acid and started taking it earlier. Ethnic differences were also seen in preconception usage (Africans, 5%; West Indians, 8%; Asians, 12%; Caucasians, 19%; P = 0.038). Participants who took folic acid supplements had significantly higher mean (SD) red cell folate concentrations than those who took none [936 (*\1.6) and 579 (*\1.6) nmol L(-1), respectively; P < 0.001]. CONCLUSIONS Folic acid supplement use preconception and prior to neural tube closure continues to be low, exhibiting both social and ethnic disparities.
Juvenile Offender Recidivism: An Examination of Risk Factors

One hundred and seventy three male juvenile offenders were followed two years postrelease from a residential treatment facility to assess recidivism and factors related to recidivism. The overall recidivism rate was 23.9%. Logistic regression with stepwise and backward variable selection methods was used to examine the relationship between recidivism and nine specific variables: offense type, age at initial involvement in juvenile justice, child welfare system involvement, termination of parental rights, parental criminal history, family support, program completion status, length of treatment stay, and discharge placement. Offender type was the only factor found to have a significant impact on recidivism with general and substance-involved offenders more likely to recidivate than sex offenders. Implications for future research are discussed.
Computer Aided Design of Drug Delivery Systems

The drug and pharmaceutical industry is a multi-billion dollar business that spends billions of dollars every year trying to optimize drugs and the way they are delivered to the body. Researchers and drug companies alike are mostly concerned with both the quantity and duration of drug presence in the body. Formulating new technologies and delivery mechanisms is a very cumbersome process that can take more time and money than is desirable. In order to arrive to improved and more efficient drug delivery mechanisms, faster and cheaper, the use of computer aided design for drug delivery systems can be utilized for the optimization of drug delivery. This involves simplifying the geometry and physics of certain drug delivery proposals, and solving equations that explain the simplified physics using computer software. The focus of this research was to use computer aided design to model certain drug delivery scenarios, with the goal in mind to optimize these drug delivery systems and their mechanisms. Our computer models can provide insight into the different mechanisms involved, and help find the different variables that can be altered for more desirable drug delivery systems. For this research, fundamental mathematical equations of transfer processes, relying heavily on mass transfer principles, between the drug delivery system and mediums were formulated. Initial conditions for the drug delivery system and their appropriate mass transfer principles were put into COMSOL Multiphysics; the software was primarily used to set up and solve our computer models. Once our computer models were designed and ready, different simulations were run changing specific variables in order to best observe how certain variables can affect a drug delivery system. These models can be used later to optimize current drug delivery systems. 1
Extended self-similarity in the numerical simulation of three-dimensional homogeneous flows.

We report the statistical analysis of several velocity configurations obtained by performing numerical simulations of three-dimensional homogeneous incompressible turbulence. This analysis provides full support to the idea, recently proposed by Benzi et al. [Phys. Rev. E 48, 29 (1993)], that fluid flows exhibit extended self-similarity, a sort of generalized scale invariance, which holds at high as well as at low-to-moderate Reynolds numbers.
OLANZAPINE POISONING: A CASE REPORT

Olanzapine is an atypical antipsychotic drug commonly used in many psychiatric illnesses. Many patients take the excess dose of their prescribed medications for intentional self harm. Although there is no specific antidote to Olanzapine over-dosage, early identification and attempt to manage such cases at earliest will restore the consciousness and decrease risk of associated morbidity and mortality. Here we present a case of suicide act of a young girl of age 20 years who was under mechanical ventilator following ingestion of 300 mg Olanzapine. Patient became stable after 48 hours of treatment in Intensive care Unit by psychiatric team.
Association of Cardiac Valve Calcification and Inflammation in Patients on Hemodialysis

Background/Aims: This study investigates the possible relationship between inflammation and cardiac valve calcification (VC) in patients on hemodialysis (HD), and identifies risk factors for VC in this patient group. Methods: Seventy-nine patients on HD (mean age, 52.2 ± 13.6 years; mean HD duration, 46.8 ± 34.3 months) were assessed echocardiographically for the presence of VC. Systolic and diastolic blood pressure (BP) values were determined. The blood parameters studied in each case were hemoglobin, blood urea nitrogen, creatinine, calcium, phosphate, calcium-phosphorous (Ca × P) product, albumin, alkaline phosphatase, intact parathyroid hormone, total cholesterol, high-density lipoprotein, low-density lipoprotein, triglyceride, lipoprotein(a), fibrinogen, and C-reactive protein (CRP). The number of patients receiving vitamin D and calcium-containing phosphate binder was determined from records, and presence of diabetes mellitus was noted. Results: Cardiac VC was detected in 36 patients (46%). Five of these patients (6%) had mitral VC, 11 (14%) had aortic VC, and 20 (25%) had calcification of both valves. The patients with VC were significantly older than those without VC (60 ± 11 vs. 43 ± 15 years, respectively; P = .001). Compared with the group without VC, the group with calcification had significantly higher systolic (145.1 ± 14.7 vs. 124.3 ± 20.7 mmHg, P = .001) and diastolic BP (91.3 ± 10.3 vs. 75.09 ± 14.9 mmHg, P = .001); significantly higher phosphate (5.1 ± 1.4 vs. 4.5 ± 1.4 mg/dL, P = 0.04), Ca × P product (48.6 ± 16.2 vs. 39.8 ± 11.8, P = .01), lipoprotein(a) [28 (15, 45) vs. 16 (5,42) mg/dL, P = . 04], fibrinogen (4.2 ± 1.2 vs. 3.5 ± 0.9, P = .005), and CRP levels [9 (4, 19) vs. 5 (3, 11) mg/L, P = . 05]; and significantly longer HD duration [49 (27, 99) vs. 26 (17, 52) month, P = . 01). Apart from age, duration of HD, systolic and diastolic BP, and Ca × P product, VC was associated with CRP (odds ratio, 1.151; P = .007) and fibrinogen (odds ratio, 1.119; P = .005). Conclusions: The results confirm well-known risk factors for cardiac VC in HD patients, such as older age, longer HD duration, elevated BP, and high Ca × P product. In addition, they suggest that elevated levels of CRP and fibrinogen were associated with VC in the HD population.
Rice bran as an efficient substrate for laccase production from thermotolerant basidiomycete Coriolus versicolor strain RC 3

Suitable substrates for laccase production by the thermotolerant basidiomycete Coriolus versicolor strain RC3 were screened using solid and liquid media. In liquid basal medium, 1%(w/v) rice bran as a carbon source was found to be the most efficient substrate for laccase production compared to 1%(w/v) glucose, wheat bran and rice straw meal. After 15 days cultivation at 37°C in shake flask culture, the extracellular laccase activity was found to be 0.22U/ml with rice bran, while 0.09, 0.01 and 0.01U/ml were obtained from wheat bran, glucose and rice straw meal, respectively. The optimum concentration of rice bran was 1%(w/v). Comparison of laccase production on three different selected solid substrates including rubber wood meal (Heavea sp.), Hang nok yoong wood meal (Delonix regia) and rice bran, were carried out using 5g of solid substrate supplemented with 15ml of distilled water and cultivated at 37°C in the dark for 30 days. Laccase production from C. versicolor strain RC3 was 1.98, 0.06 and 0.07U/g substrate from rice bran, rubber wood meal and Hang nok yoong wood meal, respectively. The highest laccase productivity with rice bran in liquid medium was 22U/g substrate at 15 days cultivation. This was 11 times higher than the maximum activity obtained at 30 days on solid substrate cultivation.
Proteome Alterations in Rat Mitochondria Caused by Aging

Abstract: Analysis of the protein profile of mitochondria and its age‐dependent variation is a promising approach to unravel mechanisms involved in aging and age‐related diseases. Our studies focus on the mammalian mitochondrial membrane proteome, especially of the inner mitochondrial membrane with the respiratory chain complexes and other proteins possibly involved in life‐span control and aging. Variations of the mitochondrial proteome during aging, with the emphasis on the abundance, composition, structure, and activity of membrane proteins, are examined in various rat tissues by native polyacrylamide gel electrophoresis techniques in combination with MALDI‐TOF mass spectrometry. In rat brain, age‐modulated differences in the abundance of various mitochondrial and nonmitochondrial proteins, such as Na,K‐ATPase, HSP60, mitochondrial aconitase‐2, V‐type ATPase, MFoF1 ATP synthase, and the OXPHOS complexes I–IV are detected. During aging, a decrease in the amount of intact MFoF1 ATP synthase occurs in the cortex. As analytical technique, native PAGE separates not only individual proteins but also multi‐subunit (membrane) proteins, (membrane) protein supercomplexes as well as interacting proteins in their native state. It reveals the occurrence and architecture of supramolecular assemblies of proteins. The age‐related alterations in the oligomerization of the MFoF1 ATP synthase observed by us in rat cortex might be one clue for understanding the link between respiration and longevity. Also, the abundance of OXPHOS supercomplexes, that is, the natural assemblies of the respiratory complexes I, III, and IV into supramolecular stoichiometric entities, such as I1III2IV0‐4, can differ between young and aged cortex tissue. Age‐related changes in the supramolecular architecture of OXPHOS complexes might explain alterations in ROS production during aging.