Miracle-dz/UniFAR-FTUs huggingface dataset:
The Correlation Between Anti-Müllerian Hormone Concentrations and Reproductive Parameters in Different Age Groups in Purebred Arabian Mares

The objectives of this study were to examine correlations of serum anti-Müllerian hormone (AMH) levels with age, ovarian function and fertility performance in purebred Arabian mares and to assess the potential use of AMH concentrations as a fertility indicator for the selection of breeder animals. For this purpose, thirty-six non-lactating purebred Arabian mares with no previous fertility problems constituted the material of the study. The animals were assigned to groups according to their age: Group I (aged 4-8 years), group II (9-18 years) and group III (19-25 years). Mean serum AMH concentrations were significantly higher (P<0.001) in group II (0.873±0.096 ng/mL) than in groups I (0.466±0.051 ng/mL) and III (0.347±0.068 ng/mL). Furthermore, serum AMH concentration was positively correlated with the daily increase in ovarian follicle diameter as well with mares with higher conception rates. It was also negatively correlated with anovulation and number of mating per conception. In summary, a strong relationship was found between peripheral AMH concentrations and fertility performance in purebred Arabian mares.
[ SSC 19-WKVIII-04 ] Folded Lightweight Actuator Positioning System ( FLAPS )

Precision actuation of mechanical structures on small spacecraft is challenging. Current solutions include single-use actuators, which rely on pyrotechnics and springs, and multiple-use actuators, which typically consume more size, weight, and power than available on CubeSats. The Folded Lightweight Actuated Positioning System (FLAPS) demonstrates the use of a simple rotary shape memory alloy (SMA) actuator in a bending architecture, along with a feedback control loop for repeatable and precise deployment. The FLAPS mechanism consists of a pair of SMA strips mounted to a hinge assembly, with one side attached to the CubeSat bus and the other to the deployable element. A custom actuator shape was manufactured using oven annealing. SMA actuation is achieved using joule heating. Feedback control is provided by a closed-loop PID control scheme, feedback sensor, and controller board. The FLAPS actuator is currently being developed for CubeSat solar panel positioning and drag control. Other potential FLAPS applications include aperture repositioning, deployable radiators, and steerable antennas. The FLAPS team will validate the actuator system in a microgravity environment on a parabolic flight in late 2019.
The Autonomous Precision Landing and Hazard Detection and Avoidance Technology (ALHAT)

As NASA plans to send humans back to the Moon and develop a lunar outpost, technologies must be developed to place humans and cargo safely, precisely, repeatedly, on the lunar surface with the capability to avoid surface hazards. Exploration Space Architecture Study requirements include the need for global lunar surface access with safe, precise landing without lighting constraints on terrain that may have landing hazards for human scale landing vehicles. Landing accuracies of perhaps 1,000 meters for sortie crew missions to 10’s of meters for Outpost class missions are required. The Autonomous precision Landing Hazard Avoidance Technology (ALHAT) project will develop the new and unique descent and landing Guidance, Navigation and Control (GNC) hardware and software technologies necessary for these capabilities. The ALHAT project will qualify a lunar descent and landing GNC system to a Technology Readiness Level (TRL) of 6 capable of supporting lunar crewed, cargo, and robotic missions. The (ALHAT) development project was chartered by NASA Headquarters in October 2006. The initial effort to write a project plan and define an ALHAT Team was followed by a fairly aggressive research and analysis effort to determine what technologies existed that could be developed and applied to the lunar landing problems indicated above. This paper describes the project development, research, analysis and concept evolution that has occurred since the assignment of the project. This includes the areas of systems engineering, GNC, sensors, sensor algorithms, simulations, fielding testing, laboratory testing, Hardware-In-The-Loop testing, system avionics and system certification concepts.
Clinical outcomes of transarticular and lateral vertebral canal lumbar interbody fusion for lumbar spinal stenosis : a retrospective study of 124 cases

To explore the effectiveness and safety of transarticular and lateral vertebral canal lumbar interbody fusion (TLc-LIF) for the treatment of lumbar spinal stenosis. Clinical data from 124 patients with lumbar spinal stenosis who underwent transarticular and lateral vertebral canal lumbar interbody fusion operations from January 2011 to March 2014 were analyzed retrospectively. The operation duration, blood loss, and postoperative complications were recorded. The visual analog scale, Japanese Orthopedic Association score and Macnab criteria were used to evaluate the clinical efficacy. All patients were followed-up through outpatient review or telephone calls, and the mean follow-up interval was 36.2 months. The mean operative duration was 146.21±34.20 min. The mean blood loss was 496.85±114.74 ml. According to the Macnab scoring criteria, the clinical outcome was excellent in 69 patients (55.65%), good in 47 patients (37.90%), acceptable in 8 patients (6.45%), and worse in none of the patients. The rate of excellent or good patient outcomes was 93.55%. The score on the visual analog scale decreased significantly between pre-operative and post-operative measurements, and the Japanese orthopedic association score increased between the pre-operative stage and follow-up. The differences between preand postoperative scores for both scales were statistically significant (P<0.05). TLc-LIF has increased potential with broadly developing prospects; thus, it would be beneficial for these procedures to be applied on a more widespread basis due to their advantages in the treatment of lumbar spinal stenosis, including minimal trauma, decreased bleeding, and high satisfaction.
Simple conditions for mixing of infinitely divisible processes

Let (X,)t~ x be a real-valued, stationary, infinitely divisible stochastic process. We show that (X~),c r is mixing if and only if Ee i(x' Xo~ ~ iEeiXo]2, provided the L6vy measure of X o has no atoms in 2~E. We also show that if (X,),~ T is given by a stochastic integral with respect to an infinitely divisible measure then the mixing of(X,)t~ x is equivalent to the essential disjointness of the supports of the representing functions.
Dosing of Education for Patients Newly Diagnosed with Multiple Sclerosis

The value of patient education has been widely documented in various patient populations. The main focus of this study is to evaluate the timing of patient education in correlation with the time since diagnosis. The goal of this study is to make recommendations for the optimal time in which patient education should be delivered following a diagnosis of Multiple Sclerosis (MS). This study evaluates self-advocacy using the Patient Self-Advocacy Scale (PSAS) which was completed pre and post educational programs. This data, combined with demographic data was analyzed for any relationships. Although no statistically significant findings were established, many important trends in data were noted which support the need for patient education.
Reinventing Love?

Affective and sexual intimacy are sensitive issues in the Arab World. However moments of closeness between men and women have always been possible, perhaps even more so today, thanks to the spread of mixed-gender social spaces and new communication technologies. Further, while undeniably embedded in gendered relations of power, love is a highly ambivalent field of experience that involves a good deal of negotiation between partners and with family and can stand in tense relationship to ideals of patriarchal domination. Often, however, romantic love is contrasted with love after marriage. This book precisely explores the relationship between love and marriage in the contemporary Arab world. By sketching the paths of amorous encounters in the Arab world, it introduces the reader to the conflicting configurations that shape love practices, providing new insights into a still-emerging field of inquiry. It examines notions of gender, intimacy and love through ethnographic case studies that offer an insight into current dynamics in Egypt, Mauritania, Morocco, Oman, Palestine, Tunisia and the United Arab Emirates.
- 101 RC 1 Evidence-based practice : performing and using systematic reviews

This lecture covers the basic principles of systematic reviews and meta-analyses and their role in the process of evidence-based decision making. The problems associated with traditional narrative reviews are discussed, as is the role of systematic reviews in limiting bias associated with the assembly, critical appraisal, and synthesis of studies addressing specifi c clinical questions. The relevant steps in writing a systematic review from the formulation of an initial research question to sensitivity analyses in conjunction with the combined analysis of the pooled data are described. Important issues that need to be considered when appraising a systematic review or meta-analysis are outlined, and some of the terms used in the reporting of systematic reviews and meta-analyses, such as relative risk, confi dence intervals, the Forest plot or the L`Abbé plot, are introduced.
Long-Term Monitoring of Giardia as an Etiological Agent for Food-Borne Outbreaks in USA : A Brief Report Case Report

Giardiasis is one of the common outbreaks that are caused by genus Giardia which belongs to subfamily Giardiinae. National Outbreak Reporting System (NORS) is a web-based platform database provides detailed outbreaks information by Centers for Disease Control and Prevention (CDC) that helps in the analysis of epidemiological diseases. Nevertheless, statistical process control software provides an indispensable tool for the processing of these records to derive useful information, future preventive actions and learning lessons. The study showed that Giardia duodenalis is the most common cause of Giardiasis with almost 80% of outbreaks occurred between June and November during 20 years of monitoring from 1998 to 2017. More than 80% of outbreaks have occurred in the years 2006, 2009 to 2015 and 2017. The non-normally distributed illness cases of the outbreaks followed Weibull (3) spreading with few cases of the spiking for the number of ill individuals in some recorded outbreaks. More than 65% of overall Giardiasis outbreaks are centered in New York, California and Pennsylvania. However, foodborne Giardiasis showed different order with 60% of outbreak cases involving New York, Pennsylvania, Wisconsin, California, Illinois, and Utah. This protozoan disease is disseminated primarily by water (>65% recreational, environmental and drinking) then food with these modes of transfer accounts by more than 70% of the total potential sources. Most of the recorded settings of occurrence were restaurants, camps, religious places, parks, child day care and private residences or homes. From trending charts, the outbreaks magnitudes tend to decrease but increase in frequency.
ON A CLASS OF LINEAR STOCHASTIC HEAT EQUATIONS DRIVEN BY SPACE-TIME WHITE NOISE

We give the explicit chaos representation of the solution of a class of one dimensional stochastic bilinear heat equations with drift in the first haos and driven by a space-time white noise. The solution is a stochastic process with finite moments of all orders. The L2-Lyapunov exponents of the solution are also estimated.
BarrierFinder: recognizing ad hoc barriers

Ad hoc synchronizations are pervasive in multi-threaded programs. Due to their diversity and complexity, understanding the enforced synchronization relationships of ad hoc synchronizations is challenging but crucial to multi-threaded program development and maintenance. Existing techniques can partially detect primitive ad hoc synchronizations, but they cannot recognize complete implementations or infer the enforced synchronization relationships. In this paper, we propose a framework to automatically identify complex ad hoc synchronizations in full and infer their synchronization relationships. We instantiate the framework with a tool called BarrierFinder, which features various techniques, including program slicing and bounded symbolic execution, to efficiently explore the interleaving space of ad hoc synchronizations within multi-threaded programs and collect execution traces. BarrierFinder then uses these traces to characterize ad hoc synchronizations into different types with a focus on recognizing barriers. Our evaluation shows that BarrierFinder is both effective and efficient in doing this, and BarrierFinder is also helpful for programmers to understand the correctness of their implemented ad hoc synchronizations.
Title Effects of hyperoxia and hypoxia on the physiological traits responsible for obstructive sleep apnoea

Oxygen therapy is known to reduce loop gain (LG) in patients with obstructive sleep apnoea (OSA), yet its effects on the other traits responsible for OSA remain unknown. Therefore, we assessed how hyperoxia and hypoxia alter four physiological traits in OSA patients. Eleven OSA subjects underwent a night of polysomnography during which the physiological traits were measured using multiple 3-min ‘drops’ from therapeutic continuous positive airway pressure (CPAP) levels. LG was defined as the ratio of the ventilatory overshoot to the preceding reduction in ventilation. Pharyngeal collapsibility was quantified as the ventilation at CPAP of 0 cmH2O. Upper airway responsiveness was defined as the ratio of the increase in ventilation to the increase in ventilatory drive across the drop. Arousal threshold was estimated as the level of ventilatory drive associated with arousal. On separate nights, subjects were submitted to hyperoxia (n = 9; FiO2 0.5) or hypoxia (n = 10; FiO2 0.15) and the four traits were reassessed. Hyperoxia lowered LG from a median of 3.4 [interquartile range (IQR): 2.6–4.1] to 2.1 (IQR: 1.3–2.5) (P < 0.01), but did not alter the remaining traits. By contrast, hypoxia increased LG [median: 3.3 (IQR: 2.3–4.0) vs. 6.4 (IQR: 4.5–9.7); P < 0.005]. Hypoxia additionally increased the arousal threshold (mean ± S.D. 10.9 ± 2.1 l min−1 vs. 13.3 ± 4.3 l min−1; P < 0.05) and improved pharyngeal collapsibility (mean ± S.D. 3.4 ± 1.4 l min−1 vs. 4.9 ± 1.3 l min−1; P < 0.05), but did not alter upper airway responsiveness (P = 0.7). This study demonstrates that the beneficial effect of hyperoxia on the severity of OSA is primarily based on its ability to reduce LG. The effects of hypoxia described above may explain the disappearance of OSA and the emergence of central sleep apnoea in conditions such as high altitude. C © 2014 The Authors. The Journal of Physiology C © 2014 The Physiological Society DOI: 10.1113/jphysiol.2014. 277210 4524 B. A. Edwards and others J Physiol 592.20 (Received 9 May 2014; accepted after revision 21 July 2014; first published online 1 August 2014) Corresponding author B. A. Edwards: Sleep Disorders Research Program, Division of Sleep Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA. Email: baedwards@partners.org Abbreviations AHI, apnoea–hypopnoea index; CPAP, continuous positive airway pressure; CSA, central sleep apnoea; EEG, electroencephalography; LG, loop gain; nREM, non-rapid eye movement; OSA, obstructive sleep apnoea; UAG, upper airway gain; VRA, ventilatory response to spontaneous arousal.
CIRCADI-OMICS Systems Biology of Circadian Rhythms : An Outlook

The circadian system in higher organisms temporally orchestrates rhythmic changes in a vast number of genes and gene products in different organs. Complex interactions between these components, both within and among cells, ultimately lead to rhythmic behavior and physiology. Identifying the plethora of circadian targets and mapping their interactions with one another is therefore essential to comprehend the molecular mechanisms of circadian regulation. The emergence of new technology for unbiased identification of biomolecules and for mapping interactions at the genome-wide scale is offering powerful tools to decipher the regulatory networks underpinning circadian rhythms. In this review, the authors discuss the potential application of these genome-wide approaches in the study of circadian rhythms.
High Intensity Physical Rehabilitation Later Than 24 h Post Stroke Is Beneficial in Patients: A Pilot Randomized Controlled Trial (RCT) Study in Mild to Moderate Ischemic Stroke

Objective: Very early mobilization was thought to contribute to beneficial outcomes in stroke-unit care, but the optimal intervention strategy including initiation time and intensity of mobilization are unclear. In this study, we sought to confirm the rehabilitative effects of different initiation times (24 vs. 48 h) with different mobilization intensities (routine or intensive) in ischemic stroke patients within three groups. Materials and Methods: We conducted a randomized and controlled trial with a blinded follow-up assessment. Patients with ischemic stroke, first or recurrent, admitted to stroke unit within 24 h after stroke onset were recruited. Eligible subjects were randomly assigned (1:1:1) to 3 groups: Early Routine Mobilization in which patients received < 1.5 h/d out-of-bed mobilization within 24–48 h after stroke onset, Early Intensive Mobilization in which patients initiated ≥3 h/d mobilization at 24–48 h after the stroke onset, and Very Early Intensive Mobilization in which patients received≥3 h/d mobilization within 24 h. The modified Rankin Scale score of 0–2 was used as the primary favorable outcome. Results: We analyzed 248 of the 300 patients (80 in Early Routine Mobilization, 82 in Very Early Intensive Mobilization and 86 in Early Intensive Mobilization), with 52 dropping out (20 in Early Routine Mobilization, 18 in Very Early Intensive Mobilization and 14 in Early Intensive Mobilization). Among the three groups, the Early Intensive Mobilization group had the most favorable outcomes at 3-month follow-up, followed by patients in the Early Routine Mobilization group. Patients in Very Early Intensive Mobilization received the least odds of favorable outcomes. At 3 month follow up, 53.5%, (n = 46) of patients with Early Intensive Mobilization showed a favorable outcome (modified Rankin Scale 0–2) (p = 0.041) as compared to 37.8% (n = 31) of patients in the Very Early Intensive Mobilization. Conclusions: Post-stroke rehabilitation with high intensity physical exercise at 48 h may be beneficial. Very Early Intensive Mobilization did not lead to a favorable outcome at 3 months. Clinical Trial Registration: www.chictr. org.cn, identifier ChiCTR-ICR-15005992.
Inhalation of Primary Motor Vehicle Emissions: Effects of Urban Population and Land Area

Urban population density can influence transportation demand, as expressed through average daily vehicle-kilometers traveled per capita (VKT). In turn, changes in transportation demand influence total passenger vehicle emissions. Population density can also influence the fraction of total emissions that are inhaled by the exposed urban population. Equations are presented that describe these relationships for an idealized representation of an urban area. Using analytic solutions to these equations, we investigate the effect of three changes in urban population and urban land area (infill, sprawl, and constant-density growth) on per capita inhalation intake of primary pollutants from passenger vehicles. The magnitude of these effects depends on density-emissions elasticity ( ε e ), a normalized derivative relating change in population density to change in vehicle emissions. For example, if urban population increases, per capita intake is less with infill development than with constant-density growth if ε e is less than –0.5, while for ε e greater than –0.5 the reverse is true.
On the breakdown of boundary layer streaks

A scenario of transition to turbulence likely to occur during the development of natural disturbances in a flat-plate boundary layer is studied. The perturbations at the leading edge of the flat plate that show the highest potential for transient energy amplification consist of streamwise aligned vortices. Due to the lift-up mechanism these optimal disturbances lead to elongated streamwise streaks downstream, with significant spanwise modulation. Direct numerical simulations are used to follow the nonlinear evolution of these streaks and to verify secondary instability calculations. The theory is based on a linear Floquet expansion and focuses on the temporal, inviscid instability of these flow structures. The procedure requires integration in the complex plane, in the coordinate direction normal to the wall, to properly identify neutral modes belonging to the discrete spectrum. The streak critical amplitude, beyond which streamwise travelling waves are excited, is about 26% of the free-stream velocity. The sinuous instability mode (either the fundamental or the subharmonic, depending on the streak amplitude) represents the most dangerous disturbance. Varicose waves are more stable, and are characterized by a critical amplitude of about 37%. Stability calculations of streamwise streaks employing the shape assumption, carried out in a parallel investigation, are compared to the results obtained here using the nonlinearly modified mean fields; the need to consider a base flow which includes mean flow modification and harmonics of the fundamental streak is clearly demonstrated.