Miracle-dz/UniFAR-FTUs huggingface dataset:
Developmental patterns in the understanding of social and physical transitivity.

Transitive inferences using both a linear dimension (A is longer than B) and a nonlinear dimension (A and B are friends) were examined. In Study 1, 6- to 9-year-old children received two problems of each kind. Performance showed similar developmental progressions but nonsignificant correlations between the two tasks. Study 2 extended these results by modifying the linear transitivity problem and adding variation in both context and type of social relation. Children 7, 9, and 11 years of age were given problems requiring judgments about friendship and about nonfriends (children who were quarreling with each other) in two different social contexts. No correlations were found between social judgments and judgments concerning length. Both type of relation and context influenced judgments about social relations. These results suggest that children possess two distinct strategies for making transitive judgments that correspond to the logical structure of the underlying relations.
The pricing of audit services: evidence from the Kuala Lumpur Stock Exchange (KLSE) listed companies

In practice, audit fees are determined based on agreement, negotiation and consensus between auditee and auditor. With the exception of the Malaysian Institute of Accountants' schedule for determining minimum audit fees, no specific guideline has been issued either by the Malaysian government or other accounting bodies. This study examined the explanatory power of previously identified factors that could influence the pricing of audit services in the Malaysian setting. The factors examined included the size of company (measured either by total assets or turnover), complexity of company (measured by the number of the companies in the same group, i.e., holding, as well as subsidiaries), profitability, liquidity and leverage of auditees, audit opinion, size and location of the auditors, audit season, audit delay, and classification of the industries in which the auditees operate. Consistent with previous studies, the size and complexity of the audited companies were found to be the major determinants of audit fees.
Mechanism Underlying the Inner Membrane Retention of Escherichia coli Lipoproteins Caused by Lol Avoidance Signals*

Escherichia coli lipoproteins are localized to either the inner or outer membrane depending on the residue at position 2. The inner membrane retention signal, Asp at position 2 in combination with certain residues at position 3, functions as a Lol avoidance signal, i.e. the signal inhibits the recognition of lipoproteins by LolCDE that releases lipoproteins from the inner membrane. To understand the role of the residue at position 2, outer membrane-specific lipoproteins with Cys at position 2 were subjected to chemical modification followed by the release reaction in reconstituted proteoliposomes. Sulfhydryl-specific introduction of nonprotein molecules or a negative charge to Cys did not inhibit the LolCDE-dependent release. In contrast, oxidation of Cys to cysteic acid resulted in generation of the Lol avoidance signal, indicating that the Lol avoidance signal requires a critical length of negative charge at the second residue. Furthermore, not only modification of the carboxylic acid of Asp at position 2 but also that of the amine of phosphatidylethanolamine abolished the Lol avoidance function. Based on these results, the Lol avoidance mechanism is discussed.
A study on m-health inline with the sensors applying for a real time environment

Abstract Health care is the core of human values and is crucial that relevant health care applications are in place. There are numerous challenges that can be addressed with new technologies like IOT. One such area is Opportunistic Network. Opportunistic network is the core and the current trend in technology that can be implemented in health care systems. It can be used as an aid in sorting out the issues relevant to the health care. The data is read by sensors synchronized with the user’s personal mobile devices. The mobile application analyses the data at frequent intervals. The data is analysed and compared with a predefined data. When the variation is minimal there is no alarm that is triggered, while there is a significant variation, an alarm is triggered. This triggered alarm can be sent to the nearest health facility triggering an alert. Through a GPS tracker signal the respective device that triggered the alarm can be tracked and assistance provided. The location of the person also can be retrieved through the GPS. Picking up the location through GPS, a SMS or a phone call should be made both to the nearby hospital as well as to the next of kin related to the person. Seeking the location to pick the nearby hospital can be achieved through GPS.
Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response

The DNA damage response (DDR) is a complex signaling network that is induced by DNA lesions and vigorously activated by double strand breaks (DSBs). The DSB response is mobilized by the nuclear protein kinase ATM, which phosphorylates key players in its various branches. SFPQ (PSF) and NONO (p54) are nuclear proteins that interact with each other and have diverse roles in nucleic acids metabolism. The SFPQ/NONO heterodimer was previously found to enhance DNA strand break rejoining in vitro. Our attention was drawn to these two proteins as they interact with the nuclear matrix protein Matrin 3 (MATR3), which we found to be a novel ATM target. We asked whether SFPQ and NONO too are involved in the DSB response. Proteins that function at the early phase of this response are often recruited to the damaged sites. We observed rapid recruitment of SFPQ/NONO to sites of DNA damage induced by laser microbeam. In MATR3 knockdown cells SFPQ/NONO retention at DNA damage sites was prolonged. SFPQ and MATR3 depletion led to abnormal accumulation of cells at the S-phase of the cell cycle following treatment with the radiomimetic chemical neocarzinostatin. Notably, proteins involved in DSB repair via nonhomologous end-joining co-immunoprecipitated with NONO; SFPQ depletion delayed DSB repair. Collectively the data suggest that SFPQ, NONO and MATR3 are involved in the early stage of the DSB response, setting the scene for DSB repair.
Predictors of the new onset of wheezing among middle-aged and older men. The Normative Aging Study.

Characteristics potentially associated with the development of wheeze symptoms were examined in a prospective cohort study of 624 middle-aged and older men who initially denied any history of wheezing or asthma. Initial evaluation included spirometry, methacholine challenge testing, allergy skin testing with common aeroallergens, serum total IgE concentration, blood leukocyte count, blood eosinophil count, and postural heart rate change (standing minus supine). The presence or absence of wheezing symptoms at follow-up 3 yr later was assessed by questionnaire. Multiple logistic regression was used to examine initial characteristics as predictors of subsequent wheezing. Current smoking was the strongest independent predictor of the new onset of wheezing (adjusted OR, 14.3; 95% confidence interval (CI), 3.9 to 52.3). The risk of developing new wheezing also increased with age (adjusted OR, 1.6; 95% CI, 0.9 to 2.9 comparing individual subjects 10 yr apart) and postural heart rate change at the initial examination (adjusted OR, 1.8; 95% CI, 1.1 to 3.0 comparing individual subjects differing by 10 beats/min). A significant association between greater methacholine airway responsiveness (PD20FEV1 < or = 16.8 mumol versus PD20FEV1 > 16.8 mumol) and the subsequent development of wheezing was observed among nonsmokers (adjusted OR, 5.2; 95% CI, 2.0 to 13.6) but not among current smokers. Other baseline variables were not independently related to the risk of developing wheezing symptoms. These data suggest that current smoking, age, nonspecific airway responsiveness, and altered autonomic function are independently related to the risk of developing wheezing symptoms in middle-aged and older men.
The Ongoing Decline of the Cheque System

Cheque use in Australia has declined significantly over the past few decades and currently represents only a small share of non-cash payments. This decline reflects changes in the payments market as a result of technological change and customer preferences for faster, digital payments. To ensure that the payment needs of individuals and businesses continue to be met, the payments industry has embarked on a number of initiatives to manage the decline in cheque use.
Dyggve–Melchior–Clausen syndrome and Smith–McCort dysplasia: Clinical and molecular findings in three families supporting genetic heterogeneity in Smith–McCort dysplasia

Dyggve–Melchior–Clausen syndrome (DMC) (MIM 223800) and Smith–McCort dysplasia (SMC) (MIM 607326) are rare allelic autosomal recessive spondylo‐epi‐metaphyseal dysplasias (SEMDs) characterized by similar skeletal manifestations. Both phenotypes have been mapped to chromosome 18q21.1 and mutations in the DYM (dymeclin) gene were identified in 13 families with DMC and in two families with SMC. Most mutations identified in DMC predict a loss of function, while those identified in SMC are mainly missense mutations, presumably associated with residual DYM activity and a less severe phenotype. We studied three consanguineous families from Turkey, Lebanon, and Georgia, one with SMC and two with DMC and identified different homozygous DYM mutations (IVS3 194‐1G > A, 938_942delTGTCT) in the DMC families. No mutation was identified in the SMC family, possibly suggesting genetic heterogeneity of this disorder. © 2006 Wiley‐Liss, Inc.
Tobacco cessation via public dental clinics: results of a randomized trial.

OBJECTIVES We sought to compare the effectiveness of a dental practitioner advice and brief counseling intervention to quit tobacco use versus usual care for patients in community health centers on tobacco cessation, reduction in tobacco use, number of quit attempts, and change in readiness to quit. METHODS We randomized 14 federally funded community health center dental clinics that serve diverse racial/ethnic groups in 3 states (Mississippi, New York, and Oregon) to the intervention (brief advice and assistance, including nicotine replacement therapy) or usual care group. RESULTS We enrolled 2549 smokers. Participants in the intervention group reported significantly higher abstinence rates at the 7.5-month follow-up, for both point prevalence (F(1,12) = 6.84; P < . 05) and prolonged abstinence (F(1,12) = 14.62; P < . 01) than did those in the usual care group. CONCLUSIONS The results of our study suggest the viability and effectiveness of tobacco cessation services delivered to low-income smokers via their dental health care practitioner in community health centers. Tobacco cessation services delivered in public dental clinics have the potential to improve the health and well-being of millions of Americans.
THE PERCEPTION OF ESTATE MANAGEMENT STUDENTS OF COVENANTUNIVERSITY TO THE COURSE VALUATION: COMPREHENSIBLE OR NOT?

Valuation is very important to the real estate profession. It is a veritable tool for decision making in property transaction and require that opinion of values given for an interest in landed property by practitioners are reliable and consistent. However, the study of valuation by university students appears to have generated bias over the years. The failure rate in valuation compared to other courses seems to be higher. The aim of this paper is to examine the Perception of Estate Management students to the study of valuation. Estate management students of covenant university students from 200 to 500 levels (being the levels offering valuation as a subject) were adopted as population sample for the study. Structured questionnaires were analyzed and the simple descriptive statistics were used for the study. The outcome of the study shows that some of the students are not fully aware of the course- Estate Management but were compelled to study it and as such are not enjoying some of the subjects particularly valuation while some are aware but find valuation particularly difficult and the others are of the opinion that valuation is very interesting. It recommends that more orientation should be given to students about the different discipline and the courses / subjects that make up the study before embarking on such a study at the university
High Incidence of Diabetic Nephropathy in Early-Onset Japanese NIDDM Patients: Risk analysis

OBJECTIVE Because early-onset Japanese NIDDM patients (diagnosed before age 30 years) can develop diabetic end-stage renal failure (ESRF) in their thirties, this study was performed to elucidate the incidence and determinants for the development of diabetic nephropathy. RESEARCH DESIGN AND METHODS The incidence of diabetic nephropathy and its relationship to baseline characteristics and long-term metabolic control were determined in 426 early-onset Japanese NIDDM patients who were followed for a mean of 6.8 years. RESULTS Of these 426 patients, 41 developed diabetic nephropathy manifested by persistent proteinuria (incidence rate [95%CI]/1,000 person-years; 14.1 [10.4–19.1]). Among patients whose mean HbA1c (measured by a high-performance chromatography method that is standardized and comparable to the one used in the Diabetes Control and Complications Trial study) was around 7% or less, few developed nephropathy. The incidence of nephropathy increased with increasing mean HbA1c level in a dose-dependent manner (χ2 trend = 49.9, P < 0.0001). Diastolic blood pressure and duration of diabetes at entry had significant predictive effects independent of metabolic control. CONCLUSIONS The incidence rate of diabetic nephropathy in early-onset Japanese NIDDM patients is potentially high, similar to or higher than that in Pima Indian NIDDM or Caucasian IDDM patients of comparable age. Diabetic nephropathy in NIDDM patients aged in their thirties or forties is likely to be an early feature that leads to ESRF, and this would contribute to the marked increase in the number of new patients with diabetic ESRF in Japan. NIDDM is a serious disease if near-normal glycemia is not achieved.
What you don't know.

Following your need to always fulfil the inspiration to obtain everybody is now simple. Connecting to the internet is one of the short cuts to do. There are so many sources that offer and connect us to other world condition. As one of the products to see in internet, this website becomes a very available place to look for countless when you don t know sources. Yeah, sources about the books from countries in the world are provided.
Potential Role for Pex19p in Assembly of PTS-Receptor Docking Complexes*

Human Pex19p binds a broad spectrum of peroxisomal membrane proteins (PMPs). It has been proposed that this peroxin may: (i) act as a cycling PMP receptor protein, (ii) facilitate the insertion of newly synthesized PMPs into the peroxisomal membrane, or (iii) function as a chaperone to associate and/or dissociate complexes comprising integral PMPs already in the peroxisomal membrane. We previously demonstrated that human Pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences. Here we demonstrate that a mutant of Pex13p that fails to bind to Pex19p nevertheless targets to and integrates into the peroxisomal membrane. In addition, through in vitro biochemical analysis, we show that Pex19p competes with Pex5p and Pex13p for binding to Pex14p, supporting a role for this peroxin in regulating assembly/disassembly of membrane-associated protein complexes. To further examine the molecular mechanism underlying this competition, six evolutionarily conserved amino acids in the Pex5p/Pex13p/Pex19p binding domain of Pex14p were subjected to site-directed mutagenesis and the corresponding mutants functionally analyzed. Our results indicate that the physically overlapping binding sites of Pex14p for Pex5p, Pex13p, and Pex19p are functionally distinct, suggesting that competition occurs through induction of structural changes, rather than through direct competition. Importantly, we also found that amino acid substitutions resulting in a strongly reduced binding affinity for Pex13p affect the peroxisomal localization of Pex14p.
Can Strong Corporate Governance Selectively Mitigate the Negative Influence of 'Special Interest' Shareholder Activists? Evidence from the Labor Market for Directors

The motivation behind labor union and public pension fund activism is widely debated. We posit that activism motivated by private benefits primarily arises when there is a firm-specific conflict of interest, such as when a union activist also represents workers in collective bargaining negotiations. We provide evidence that the labor market for directorships mitigates the negative effect of “special interest” activism on other shareholders. Specifically, directors who cater to self-serving requests are punished with a loss in directorships and damage to their reputation as corporate monitors. Moreover, we provide insight into when boards are most vulnerable to “special interest” pressure.
Optimization and Performance Analysis of Interferometric GNSS-R Altimeters: Application to the PARIS IoD Mission

Reflectometry using Global Navigation Satellite System's signals (GNSS-R) of opportunity was originally conceived in the early 1990 s for mesoscale altimetry, and since then, many studies have shown its applicability to other remote sensing applications such as sea state determination, soil moisture, vegetation, snow monitoring, etc. In December 2012, the Phase A studies of ESA's PAssive Reflectometry and Interferometry System In-orbit Demonstration (PARIS IoD) mission concluded. In conventional GNSS-R (cGNSS-R), the satellite navigation signals scattered over the Earth's surface are cross-correlated with a locally generated replica of the transmitted ones shifted in frequency (Δfd), and in delay (Δτ). However, in PARIS, a different technique called interferometric GNSS-R (iGNSS-R) is used, which allows the use of the whole signal's bandwidth, and improve the altimetry precision, despite the large bandwidth signals' codes being not publically available. This is achieved by using the direct signal collected by a directive antenna, instead of the locally generated replica. This study presents a methodology to optimize the configuration of a generic iGNSS-R altimeter, and evaluate its performance. The methodology presented is then particularized to a PARIS IoD-like case.
Exploring Culture Factors Affecting the Adoption of Mobile Payment

The mobile payment represents an extremely interesting paradox in the world of mobile telecommunications, still not showing success in China. It is showed that there is a certain link between the national culture and the use of mobile payment. But mobile payment studies related to national culture are limited. Our research specifically focuses on the effects of the national cultural on the acceptance of mobile payment. The study employs the Technology Acceptance Model (TAM) to explore factors affecting consumers' intentions. And for exploring the impact of culture on mobile payment acceptance, we adopt Hofstede's cultural dimensions as moderators to extend the TAM model. The scale questionnaire is designed for the improved model.
Electrooculogram Based Online Control Signal Generation for Wheelchair

Human computer interfacing technology has paved a new way in providing services to people with special needs (i.e., elderly, people with impairments, or people with disabilities). Research is going on to interface the movement based biosignals with machines. Electrooculogram is the signal produced due to eye ball movements and can be used to control mobility aids. Electrooculogram is the potential difference around the eyes due to movement of the eye balls in different directions. In this study an acquisition system for electrooculogram is designed to collect the desired signal with low noise and then signal processing is done for control application. The contribution of this paper lies in the development of two new strategies of electrooculographic signal based control of motors in real time.
Let it go - Consumer empowerment and user generated content: an exploratory study of contemporary fashion marketing practices in the digital age

The various digital interactions and contributions, which can be grouped under the umbrella term User Generated Content (UGC), can take the form of product reviews, blogs, demonstration of product usage or even “homemade advertising” (Berthon, Pitt, & Campbell, 2008; Fader & Winer, 2012). While current studies on UGC have mainly focused on the motivations that drive consumers to engage and contribute in various forms online, this research aims to explore how are organisations operating within the fashion industry are listening to, and taking advantage of, the various consumers contributions defined as UGC in order to innovate and create value for customers and other stakeholders. The findings of the semi-structured interviews conducted show that managers are still struggling in balancing the level of control and in managing a new generation of empowered consumers (Pires, Stanton, & Rita, 2006). Social media and UGC call for a more strategic approach by organisations wishing to succeed. The relationship between UGC and co-innovation was also identified.
Adoption of the agri-environmental measures: The role of motivations and perceived effectiveness

This paper investigated farmers’ self-stated adoption motives and the perceived effectiveness of agri-environmental measures in Finland. The measures were classified into ten distinct categories according to their prescriptions. The adoption motives were related to contextual factors, production factors and perceived effectiveness of the measures, while effectiveness was further related to land use, input use and the final impacts. The results indicate that the adoption motivations and the perceived effectiveness of the measures are related to their prescriptions: measures targeting the same problem with different prescriptions fit the aims and farming strategies of different farmers.
Ecological distribution of Legionella pneumophila

Bacteria were concentrated 500-fold from 20-liter water samples collected from 67 different lakes and rivers in the United States. The data suggest that Legionella pneumophila is part of the natural aquatic environment and that the bacterium is capable of surviving extreme ranges of environmental conditions. The data further demonstrate the effectiveness of the direct fluorescent-antibody technique for detecting L. pneumophila in natural aquatic systems. Smears of the concentrated samples were screened microscopically for serogroups of L. pneumophila by the direct fluorescent-antibody technique. Virtually all of the 793 samples were found to be positive by this method. The 318 samples containing the largest numbers of positive bacteria which were morphologically consistent with L. pneumophila were injected into guinea pigs for attempted isolations. Isolates were obtained from habitats with a wide range of physical, chemical, and biological parameters. Samples collected monthly from a thermally altered lake and injected into guinea pigs demonstrated a seasonality of infection, with the highest frequency of infection occurring during the summer months.