Miracle-dz/UniFAR-FTUs huggingface dataset:
Travel decision reversals paradox of competitive metro lines: The Equate-to-differentiate Theory Interpretation

Based on the equate-to-differentiate theory, this paper studies the paradox of preference reversal and choice reversal in traffic decision-making in parallel sections of Chengdu Metro Line No.2 and No.4. Travel decision reversals: preference reversals phenomenon (PRP) and choice reversals phenomenon (CRP) are found in the travel investigation for Chengdu Metro Line No.2 and No.4, and the reversals cannot be well explained by random error. Through experimental design of cautious control, the existence of these phenomena is confirmed. This paper establishes the judgment dimension system of option attributes, and designs three groups of psychological experiment in certain, uncertain and risk scenarios. Data analysis shows that PRP and CRP can be explained by the equate-to-differentiate interpretation. The phenomena of reversal are not due to the fact that preference and choice really reverses, but the variable strategic process. The equate-to-differentiate interpretation shows good consistency in the experiments and can predict and explain the preference and choice reversal of travel decision. At last, a comparative analysis which compares the results of the two models of the decision field theory is made and finally the conclusion is obtained.
Malignant Melanoma In Cameroon

Introduction: Little information is available on the characteristics and epidemiology of malignant melanoma in Cameroon and sub-Saharan Africa in general. The absence of accurate information prompted this study. A rising trend in the incidence of malignant melanoma has been highlighted, especially in developed countries. Materials and Methods: Over a period of 9 years (December 1996 to August 2005), we evaluated patients with malignant melanoma diagnosed clinically and confirmed by histopathology in our Dermatology and Surgical Clinics. Data evaluated included information on age, sex, delay in presentation, sites of lesions, available treatment and survival. Results: Over eight years 560 cases of cancer were diagnosed, (57/560) 10.2% of which were skin cancers and (25/560) 4.46% were confirmed malignant melanoma. Most of the lesions (21/25) 81% were on the lower limbs. 3 lesions were buccal and 1 abdominal. 20/25 (80%) were on the soles of the feet. 8 patients (32%) presented with advanced disease and generalized metastases. Two year survival rate was 35%. Local excision was offered to 8patients with relapses in 4 of them within 6 months. Conclusion: Malignant melanoma represents 4.46% of all cancers registered and is the most frequent skin cancer. The prevalence of malignant melanoma might be higher than our present findings. The anatomical distribution and the advanced stage of disease at presentation reflect the pattern of malignant melanoma in black populations elsewhere. An awareness campaign will provide enlightenment to the black cancer. This will lead to early presentation and improved survival.
Characterization of the complete mitochondrial genome sequence of Nibea diacanthus and its phylogenetic implication

Abstract The blackspotted croaker (Nibea diacanthus) is an important food fish of Indo-West Pacific and China. To study the phylogenetic status, we sequenced the complete mitochondrial genome of N. diacanthus. The mitogenome is 16,532 bp in length and composed of 13 protein-coding genes, two rRNAs, 22 tRNAs, and a control region. The gene composition and the structural arrangement of N. diacanthus complete mtDNA were identical to most of other vertebrates. The phylogenetic analysis using the complete mitochondrial genome revealed that the N. diacanthus might be separated from Nibea genera of Argyrosominae, which was inconsistent with that based on morphology. The complete mitogenome data would be useful for the evolution and conservation genetic studies of Sciaenidae.
The Value Premium

Value premiums, which we define as value portfolio returns in excess of market portfolio returns, are on average much lower in the second half of the July 1963–June 2019 period. But the high volatility of monthly premiums prevents us from rejecting the hypothesis that expected premiums are the same in both halves of the sample. Regressions that forecast value premiums with book-to-market ratios in excess of market (BM–BMM) produce more reliable evidence of second-half declines in expected value premiums, but only if we assume the regression coefficients are constant during the sample period. Received: January 21, 2020; editorial decision: July 21, 2020; Editor: Jeffrey Pontiff.
Technological advances in molecular pathology : a journey into the archives

Pathology laboratories throughout the world have compiled large archives of unique collections of tissue specimens. These tissue samples are used for patient diagnostics and research. Novel molecular insights into alterations in normal cellular function have led to the identification of targets for innovative therapies. Testing for biomarkers combined with molecular pathology has created the potential for “personalized medicine” and improved diagnosis, treatment and prognosis. New technologies for molecular analysis in molecular tumor diagnostics and research must be developed and implemented to keep pace with the latest insights, resulting in a constant cycle of change. Such translational research can only progress if patient material can be accessed from the archives for further study. The resulting new insights and strategies will eventually be implemented in patient care. This thesis describes three important issues in this cycle of change with a focus on molecular pathology. Tissue preparation, method development and data analysis.
Epidemiological And Molecular Aspects On Cholera

Thank you for downloading epidemiological and molecular aspects on cholera. Maybe you have knowledge that, people have look numerous times for their favorite books like this epidemiological and molecular aspects on cholera, but end up in malicious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they are facing with some infectious virus inside their computer.
Comparison of bacterial adhesion and biofilm formation on zirconia fabricated by two different approaches: An in vitro and in vivo study

Prepared by dry and wet approaches, respectively, the surface properties and bacterial adhesion of conventional zirconia (CZ) and self-glazed zirconia (SGZ) were investigated. Each zirconia was divided into unpolished and polished groups. Our results revealed that SGZ showed significantly lower surface roughness than CZ (P < 0.05) and lower surface-free energy (P < 0.05) in both polished and unpolished groups. The number of bacteria attached to SGZ was less than CZ in vitro (P < 0.05), but no significant difference was found between two kinds of zirconia in vivo (P > 0.05). Our findings suggest that SGZ, due to its excellent surface characteristics, is superior to CZ in bacterial adhesion and zirconia polishing serves as an indispensable procedure in clinics.
Detection of Mammary Tuberculosis in Slaughtered Cattle and Consequent Risk of Zoonosis to Human in Nigeria

Tuberculous lesions are often more confined to thoracic region and associated lymph nodes than other body parts, as mostly documented in the surveillance studies of cattle tuberculosis in Nigeria. We report a detection of combined pulmonary and a rare extra-pulmonary (mammary) tuberculosis in two zebu cows slaughtered for human consumption. Tubercle bacilli may be disseminated to different anatomic locations in diseased animals, zoonotic transmission of these infective bacilli is predominantly acquired by consumption of unpasteurized milk and its products and poorly processed meat from diseased animals. The risks of intra-and-inter species exposure to tuberculosis as it relates to predominant livestock husbandry, eating habits and food preference in Nigeria were discussed.
Population pharmacokinetics (popPK) to evaluate the effect of intrinsic and extrinsic factors on regorafenib (REG) exposure in REG studies including patients with hepatocellular carcinoma (HCC).

320Background: REG is approved for refractory metastatic colorectal cancer (CRC) and gastrointestinal stromal tumors (GIST). In the phase 3 RESORCE trial (N = 573), REG (160 mg QD, 3 weeks on/1 week off) significantly (P 0.05) influence exposure, whereas covariates significantly (p.
Appropriate adaptation of precision agriculture technology in open field cultivation in tropics

Tropical agriculture production is profoundly affected by the uncontrollable environmental condition. To obtain good agricultural products, farmers manage their farm to fit with the variation of weather and season. The farming managements are generally determined according to farmers personal knowledge, gained from the long-term experience from preceding years. Nowadays, climate change intensifies unpredictable weather and its unstable distribution. Consequently, conventional farming management considering the climate change factor should be considered. The farming management should face the dynamic change of weather condition as well as improve the farmer’s knowledge towards the implementation of precision agriculture approach. The objective of this study was to introduce an appropriate adaptation of precision agriculture technology by the utilization of information and communication technology (ICT) to improve conventional farming management in tropical agriculture production. The framework is implementing cloud technology as a backbone, which can be extended with various knowledge such as data science, plant biology, plant physiology, biophysical, and biomechanical. The appropriate adaptation of precision agriculture represented by the improvement of the conventional farming method using the technological aspect by fostering their knowledge to adopt modern agriculture empowered with Information and Communication Technology (ICT). Learning process from data-information-knowledge on the application of precision agriculture will be documented at the PA Knowledge Management System.
THE VIETNAM SYNDROME IN FORREST GUMP MOVIE SCRIPT

Considered the most controversial war in the 20th century, the Vietnam War deeply divides the American society. Especially, it causes the Vietnam Syndrome which still is an obsession of American people until today. The research is carried out on a movie script of one of the most famous Hollywood films about the Vietnam War, Forrest Gump. The collected data are analyzed on the basis of Fairclough’s threedimensional framework for critical discourse analysis (CDA). The study aims to reveal the different aspects of the syndrome considered as a psychological trauma expressing in many factors such as the topic, the plot, the characters, the setting, the genre, the theme songs, and the language of the whole movie. Moreover, the movie script exposes a long period of problematic and tragic time in the history of the United States.
Physiological Motion Artifacts in Capacitive ECG: Ballistocardiographic Impedance Distortions

Capacitive electrocardiogram (cECG), a tried and tested technique for more than 50 years, can replace the gold standard electrocardiogram (ECG) only in certain applications, where unobtrusiveness is aimed at the expense of reduced signal quality. This inferiority is due, among other reasons, to the fragility of the capacitive coupling between the body and the electrode, observed as motion artifacts in the presence of time-variant coupling capacitance. Attempts were made to remove these artifacts in earlier studies using adaptive noise cancellation by assuming statistical independence between motion and ECG signals. This article considers the mechanical vibrations of the human body itself as the source of time-variant coupling capacitances, which can cause motion artifacts. Ballistocardiography (BCG) measurements on cECG electrodes were recorded and analyzed to investigate how these mechanical vibrations influence the coupling impedance of the clothing between the body and the electrode. A novel sensor has been proposed and tested in a test bench for four different nominal pressure values (15, 20, 25, and 30 mmHg) with minute-increasing steps for the measurement of the coupling capacitance. Subsequently, simultaneous measurements of BCG and the coupling capacitance were conducted on three healthy subjects for two different electrode positions. A significant correlation between the coupling capacitance and measured ballistocardiograms was found both in time-domain shapes and time–frequency distributions in all measurements.
Synthesis and in vivo evaluation of pyrazoline-thiazolidin-4-one hybrid Les-5581 as a potential non-steroidal anti-inflammatory agent

© 2019 S. М. Holota et al.; Published by the Institute of Molecular Biology and Genetics, NAS of Ukraine on behalf of Biopolymers and Cell. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited
Semisupervised Multilabel Deep Learning Based Nonintrusive Load Monitoring in Smart Grids

Nonintrusive load monitoring (NILM) is a technique that infers appliance-level energy consumption patterns and operation state changes based on feeder power signals. With the availability of fine-grained electric load profiles, there has been increasing interest in using this approach for demand-side energy management in smart grids. NILM is a multilabel classification problem due to the simultaneous operation of multiple appliances. Recently, deep learning based techniques have been shown to be a promising approach to solving this problem, but annotating the huge volume of load profile data with multiple active appliances for learning is very challenging and impractical. In this article, a new semisupervised multilabel deep learning based framework is proposed to address this problem with the goal of mitigating the reliance on large labeled datasets. Specifically, a temporal convolutional neural network is used to automatically extract high-level load signatures for individual appliances. These signatures can be efficiently used to improve the feature representation capability of the framework. Case studies conducted on two open-access NILM datasets demonstrate the effectiveness and superiority of the proposed approach.
Histone modification dynamics as revealed by a multicolor immunofluorescence-based single-cell analysis

Post-translational modifications on histones can be stable epigenetic marks and transient signals that can occur in response to internal and external stimuli. Levels of histone modifications fluctuate during the cell cycle and vary among different cell types. Here we describe a simple system to monitor the levels of multiple histone modifications in single cells by multicolor immunofluorescence using directly labeled modification-specific antibodies. We first analyzed histone H3 and H4 modifications during the cell cycle. Levels of active marks, such as acetylation and H3K4 methylation, were increased during the S phase, in association with chromatin duplication. By contrast, levels of some repressive modifications gradually increased during the G2 and the next G1 phases. We applied this method to validate the target modifications of various histone demethylases in cells using a transient overexpression system. We also screened chemical compounds in marine organism extracts that affect histone modifications and identified psammaplin A, which was previously reported to inhibit histone deacetylases. Thus, the method presented here is a powerful and convenient tool for analyzing the changes in histone modifications.
Periodontal regeneration by application of recombinant human bone morphogenetic protein-2 in human periodontal intraosseous defects: A randomized controlled trial

Background: Recombinant human bone morphogenetic protein-2 (rhBMP-2) technologies have been shown to significantly support alveolar bone. The purpose of this study was to explore the effect of rhBMP-2 following periodontal flap surgery in vertical defects on clinical and radiological parameters. Methods: A randomized double-blind controlled trial was carried out, wherein rhBMP-2 was used in the test group after open flap debridement (OFD). The control group was only OFD. The same examiner carried out both clinical and radiographic measurements at baseline, 6 and 9 months. Results: In rhBMP-2 + OFD sites, the probing pocket depth reduction was 1.45 ± 0.76, 2.50 ± 0.69 at 6 months and 9 months, respectively (both P < 0.001) and clinical attachment gain was 0.92 ± 0.76, 1.31 ± 0.48 at 6 months, and 9 months, respectively (both P < 0.001). Radiographic fill was 1.14 ± 0.73, 1.85 ± 0.83 at 6 months, and 9 months postoperatively (P < 0.001) and percentage of original defect resolved at 6 and 9 months was 40.2 ± 18.6, 60.1 ± 15.8, respectively. Conclusions: The periodontal therapy can include rhBMP-2 to enhance periodontal regeneration. The clinical and radiographic improvement are demonstrated in this study.
Redirecting interlukin-10 in the fibrotic liver

Purpose. Delivery of apoptosis-inducing compounds to hepatic stellate cells (HSC) may be an effective strategy to reverse liver fibrosis. The aim of this study was therefore to examine the selective targeting of the apoptosis-inducing drug 15-deoxy-D12, 14-prostaglandin J2 (15dPGJ2) with two different HSC carriers: human serum albumin modified with the sugar mannose-6-phosphate (M6PHSA) or albumin modified with PDGF-receptor recognizing peptides (pPBHSA). Methods and Results. After chemical conjugation of 15dPGJ2 to the carriers, the constructs displayed pharmacological activity and specific receptor-mediated binding to HSC in vitro. Unlike 15dPGJ2pPBHSA, the cellular binding of 15dPGJ2-M6PHSA was reduced by a scavenger receptor antagonist. In vivo, both conjugates rapidly accumulated in fibrotic livers. Intrahepatic analysis revealed that 15dPGJ2M6PHSA mainly accumulated in HSC, and to a lesser extent in Kupffer cells. 15dPGJ2-pPBHSA also predominantly accumulated in HSC with additional uptake in hepatocytes. Assessment of target receptors in human cirrhotic livers revealed that M6P/IGFIIreceptor expression was present in fibrotic areas. PDGF-b receptor expression was abundantly expressed on human fibroblasts. Conclusions. These studies show that 15dPGJ2 coupled to either M6PHSA or pPBHSA is specifically taken up by HSC and is highly effective within these cells. Both carriers differ with respect to receptor specificity, leading to differences in intrahepatic distribution. Nevertheless, both carriers can be used to deliver the apoptosis-inducing drug 15dPGJ2 to HSC in vivo.
Delivering Psychological Services to Military Members

Military members are immersed in an all-encompassing culture and required to make countless personal sacrifices, often experiencing trauma or other stressors that most civilians will never face. Over the past two decades, a grateful nation has provided unprecedented levels of support for the many brave servicemen and women who choose this career path. It may therefore come as a surprise to some that, despite this support, many military members remain underserved in the area of mental health. Challenges include system and access barriers; health providers’ lack of familiarity with military injuries, needs, and culture; and military members’ own stigma-related reluctance to seek treatment. This chapter provides mental health clinicians with suggestions for practice. We outline the challenges and detail the qualities necessary to work effectively with psychotherapy clients who are military members.
Research on Image Super-resolution Reconstruction Method Based on Improved SRCNN

Existing image convolutional neural network based on image super-resolution algorithm has a problem of image texture blurred to improve. In this paper, we first analyze the factors of reconstructed image quality, then use the parametric rectified linear unit (PRLU) to solve the problem of over-compression in the original network. And combining the existing network models and image processing algorithms adjusts the parameters of the neural network, The network model of 9-1-5 in Super-Resolution Convolutional Neural Network (SRCNN) is improved to a three-layer model of 5-3-5. The number of convolution cores in the first and second layers is adjusted to 32, and the magnification is increased by four times from three times. Finally, simulation experiments are carried out on DIV2K dataset in NTIRE2017. Experimental results show that the proposed algorithm achieves good super-resolution results, and the subjective visual effect and objective evaluation indices are both improved obviously. The image super-resolution technology has great application demand in the fields of video surveillance, virtual scene restoration and so on. There is still a great research prospect for the image super-resolution technology.
Responsible Government, Statutory Authorities and the Australian Constitution

This article examines the compatibility of extra-departmental executive agencies, a defining feature of the modern regulatory state, with responsible government, one of the architectonic principles of the Australian Constitution. Some scholars have argued that a constitutional implication derived from responsible government should be drawn limiting the types of entities that may be established by the Commonwealth and imposing requirements relating to the relationship that must exist between ministers and entities within their portfolio. This article argues that the view that independent statutory agencies are a derogation from the principles of responsible government rests on a misunderstanding of responsible government. Responsible government is an inherently evolutionary system: as incorporated into the Australian Constitution, responsible government was intended to be flexible and non-prescriptive, allowing for change in the governmental arrangements considered necessary from time to time. Independent statutory agencies should not be seen as a challenge to the true principles of responsible government but a legitimate evolution in governance arrangements, which the Constitution deliberately left open.
The Expression Gene that Have a Role in Tissue Regeneration of Digit Tip Mice (Mus musculus)

The tissue regeneration of digit tip mice needs some proteins that play a role in overcoming the inflammatory state. The protein plays a role in the continuous growth of specific cells, cell migration, functional differentiation, and tissue morphogenesis. All of the cells need energy related to cell respiration. Naturally expressing mRNA of ADAM 17, Wnt-5a, Hedgehog (HH), and Cytochrome-c (Cyt-c) reliably produced the accordance with their respective roles in each specific phase of tissue regeneration until the whole tissues formed again. The ADAM 17 genes expressed in the inflammatory phase, it positively related its essential role to the inflammatory process. Cyt-c gene expression occurs throughout the tissue regeneration the gene has a role in apoptosis cell. The Wnt-5a gene in the granulation phase and the HH gene expressed after the blastema phase. Both expressed genes positively correlate with the continual growth of the digit tip mice by the specific Spearman test (p < 0.05) because of their active role of cell proliferation, cell differentiation, extensive migration, and morphogenesis.