Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of absorption with aqueous blends of 2-amino-2-methyl-1-propanol and Piperazine for appliance to $^{14}CO_2$ absorption removal

The neutron irradiated graphite has an internal energy which has been known for the wigner energy. [1] It has been reported that it simultaneously generates gas such as, H, C, Cl, during heat treatment process for elimination wigner energy of neutron irradiated graphite and the radioactive carbon exists mostly as CO2, as gas phase. The gas, CO2, is generated during treating neutron irradiated graphite. The purpose of this work is the investigation of the blends of absorbent and absorption conditions in CO2 absorption removal and then to apply to the removal process of CO2 practically. Industrially, the amine compounds are typical absorbents in CO2 removal. Among them, we have chosen 2-amino-2-methyl-1-propanol(AMP) and Piperazine(PZ) as absorbent. In previous studies, it was reported that it improved absorption capacity and reaction rate, especially, those were affected by concentration of PZ. [2] Besides, There is a reaction that recovers PZ by the reaction of AMP and intermediate from reaction of PZ and CO2. [3]
[Single parathyroïd adenoma: cervicotomy with bilateral exploration of the neck or minimally invasive unilateral approach?].

Un patient âgé de 38 ans présente une hypercalcémie à 118 mg/l, découverte à l’occasion de son troisième épisode de coliques néphrétiques. Le patient est en bon état général, hormis une asthénie récente, il n’a pas d’autres symptômes. Le bilan est complété par une phosphorémie basse à 18 mg/l, une calciurie à 340 mg/24 heures et un taux de parathormone sanguin à 174 ng/l. L’examen du cou est normal. L’échographie cervicale montre un nodule arrondi de 16 mm de diamètre, siégeant au contact du pôle inférieur du lobe thyroïdien gauche avec lequel il ne semble pas faire corps. La thyroïde est normale. Il n’y a pas d’autre anomalie cervicale. La scintigraphie au Sesta-MIBI montre un foyer d’accumulation au pôle inférieur du lobe gauche compatible avec une lésion parathyroïdienne telle qu’elle est décrite à l’échographie. Il n’y a pas d’autre foyer d’accumulation anormale dans le cou ou le médiastin. Quel traitement proposez-vous ? Par quelle voie d’abord ?
Pigeon Pea Biochar as a Soil Amendment to Repress Copper Mobility in Soil and Its Uptake by Spinach

A pot crop experiment was conducted to study the effect of biochar on Cu mobility in a soil-plant system. Pigeon pea biochar was prepared by slow pyrolysis at 300 °C. The experiment had three levels of Cu (0, 250, and 500 mg Cu kg-1 soil) and three levels of biochar (0, 2.5, and 5 g kg-1 soil), using spinach as the test crop. The dry matter yield of edible spinach leaf decreased by 16.7% and 27.9% at 250 and 500 mg Cu kg-1 soil concentration, respectively. The soil organic carbon (SOC) increased by 27.08% and 45.83% at 2.5 and 5 g kg-1 soil application of biochar, respectively. Cu mobility in soil was significantly reduced as a result of biochar application, as evident from the reduction in DTPA extractable Cu in soil, the transfer coefficient value (soil to plant), and the Cu concentration in the leaf and root. The increases in SOC and pH in the biochar amended soil affect copper dynamics because they control adsorption and precipitation on solid phase. Cu has higher affinity towards SOC and makes stable complexes, thereby decreasing the Cu mobility in soil. Adsorption and precipitation of heavy metals to solid phases and also increasing the negatively charged functional group due to increase in soil pH resulted in reduction of Cu mobility in soil.
Remodelage vasculaire dans les modèles expérimentaux d'anévrysme de l'aorte abdominale

La physiopathologie de l’anevrysme de l’aorte abdominale (AAA) est complexe. Elle implique notamment des facteurs hemodynamiques, une proteolyse matricielle, un stress oxydatif et une reaction immune. Des modeles experimentaux ont ete mis au point pour explorer les mecanismes impliques dans la genese et la croissance des AAAs. Dans ce travail, nous explorons le role de ces modeles dans la comprehension du remodelage vasculaire des AAAs. Dans une premiere partie, une revue de la litterature sur les modeles experimentaux d’AAA est menee. Dans une seconde partie, nous explorons l’origine et le role des calcifications des AAAs experimentaux. Dans une troisieme partie, le modele de xenogreffe aortique decellularisee est utilise pour etudier le role de l’immunite adaptative dans la rupture. Notre revue identifie les principaux modeles d’AAA. Leur limite majeure est la survenue d’une cicatrisation empechant l’evolution vers la rupture. Notre exploration des calcifications anevrysmales retrouve une co-localisation des calcifications avec de l’ADN libre et un modele experimental demontre la capacite de l’ADN libre a induire des calcifications. La croissance anevrysmale est toutefois ralentie par les calcifications. Notre etude sur le modele de xenogreffe decellularisee retrouve la possibilite d’induire une rupture lorsqu’une pre-sensibilisation contre la matrice extracellulaire est realisee. Les glycoproteines de structure et les proteoglycanes semblent etre les composants matriciels en cause dans ces ruptures. Les modeles experimentaux constituent des outils majeurs pour l’etude des mecanismes impliques dans le remodelage vasculaire des AAAs.
Évaluation de la mise en œuvre d’une séance d’information à l’intention des survivantes dans le cadre d’un Programme de bien-être au-delà du cancer : portrait des participantes

Les survivantes du cancer du sein et de l’endometre orientees vers le Programme de bien-etre au-dela du cancer ont ete invitees a participer a une seance d’information, mais elles n’ont pas toutes donne suite a cette invitation. La presente etude cherche donc a determiner les caracteristiques sociodemographiques et medicales, ainsi que les besoins des survivantes, qui permettraient de predire leur participation a ce type d’atelier. Pour ce faire, un examen du dossier des survivantes ayant rempli une enquete d’evaluation des besoins entre 2012 et 2014 (n = 144, cancer de l’endometre; n = 170, cancer du sein) a ete realise. Les caracteristiques des participantes ont ete comparees a celles des femmes qui n’etaient pas presentes a l’aide de tests t, d’analyses du khi-carre et d’une analyse de regres- sion. Les analyses univariees ont montre une correlation entre la participation a la seance d’information et l’age, la proximite de l’hopital, les besoins emotionnels et physiques, et les traitements de chimiotherapie ou de radiotherapie qui avaient ete recus. La proxi- mite de l’hopital et les besoins physiques sont quant a eux ressortis comme des facteurs predictifs multivaries. Les resultats de l’etude nous permettront d’etoffer le contenu de la seance d’information, d’accroitre le taux de participation et de cerner les caracteristiques des participantes.
PWA state feedback controller synthesis for piecewise-linear systems

We propose a new technique for the design of piecewise affine(PWA) state feedback controller for piecewise-linear systems(PWL) under the consideration of the possibility for sliding motion on the boundaries between the polytopic regions, which is less conservative than existing approaches in the literatures. Using piecewise quadratic Lyapunov function and a new criterion for the avoidance of sliding motion, the stabilization problem is formulated as a numerical optimization problem under Bilinear Matrix Inequality (BMI) constraints; We demonstrate the efficacy and advantage of the algorithm through a numerical example.
An examination of the NAACCR method of assessing completeness of case ascertainment using the Canadian Cancer Registry.

BACKGROUND Despite use of the North American Association of Central Cancer Registries' indicator for assessing completeness of case ascertainment in population-based cancer registries, little has been published about its methodology, usefulness and accuracy in Canada. DATA AND METHODS Canadian cancer incidence, cancer mortality, and population census data were used to quantify case completeness in 2007. Two indicators (I₁ and I₂) that expressed the observed age-standardized incidence rate relative to the expected rate were calculated. The assumption of stable age-standardized sex- and cancer-site-specific incidence-to-mortality rate ratios across regions was assessed. Associations between I₁, I₂ and simpler indicators of completeness were examined. RESULTS The assumption of stable age-standardized sex- and cancer-site-specific incidence-to-mortality rate ratios across regions was not consistently supported—substantial regional differences emerged. I₁ was strongly correlated with I₂ (r=0.93, n=315, p<0.0001), and both were most strongly and consistently associated with the age-standardized incidence-to-mortality rate ratio. The frequency of undercoverage did not increase consistently with expected case-finding difficulty. INTERPRETATION The age-standardized incidence-to-mortality rate ratio may provide a less complicated method of identifying undercoverage.
Comparison of Filamin A-induced Cross-linking and Arp2/3 Complex-mediated Branching on the Mechanics of Actin Filaments* 210

We compared the effects of human filamin A (FLNa) and the activated human Arp2/3 complex on mechanical properties of actin filaments. As little as 1 FLNa to 800 polymerizing actin monomers induces a sharp concentration-dependent increase in the apparent viscosity of 24 μm actin, a parameter classically defined as a gel point. The activated Arp2/3 complex, at concentrations up to 1:25 actins had no detectable actin gelation activity, even in the presence of phalloidin, to stabilize actin filaments against debranching. Increasing the activated Arp2/3 complex to actin ratio raises the FLNa concentration required to induce actin gelation, an effect ascribable to Arp2/3-mediated actin nucleation resulting in actin filament length diminution. Time lapse video microscopy of microparticles attached to actin filaments or photoactivation of fluorescence revealed actin filament immobilization by FLNa in contrast to diffusion of Arp2/3-branched actin filaments. The experimental results support theories predicting that polymer branching absent cross-linking does not lead to polymer gelation and are consistent with the observation that cells deficient in actin filament cross-linking activity have unstable surfaces. They suggest complementary roles for actin branching and cross-linking in cellular actin mechanics in vivo.
Rating models and its Applications: Setting Credit Limits

In regulatory and competitive environments increasingly tight, banks have been forced to constantly improve their internal rating models. Despite the increased supply models and statistical approaches that has been proposed to them, the answer to the question: how much to lend ? remains always at the discretion of the credit risk manager. The aim of this paper is to propose a statistical approach that allows an estimation of the maximum facility bank overdraft (limits) that the credit risk manager may allow coorporate and to identify the determinants of this limits.
Life-supporting pig-to-primate renal xenotransplantation using genetically modified donors.

BACKGROUND In order to circumvent the complement-mediated hyperacute rejection of discordant xenografts, a colony of pigs transgenic for the human regulator of complement activity, human decay-accelerating factor (hDAF), has been produced. METHODS Seven kidneys from hDAF transgenic pigs and six kidneys from nontransgenic control pigs were transplanted into cynomolgus monkeys; both native kidneys were removed during the same operation. The recipient animals were immunosuppressed with cyclosporine, steroids, and cyclophosphamide. RESULTS In the transgenic group, the median survival time was 13 days (range, 6-35 days); the median survival time in the control group was 6.5 days (range, 0.3-30 days). There were no cases of hyperacute rejection in the transgenic group, and the two longest-surviving kidneys in this group showed no evidence of rejection on histological examination. In contrast, all control kidneys underwent antibody-mediated rejection, one demonstrating hyperacute rejection and the others acute vascular rejection. CONCLUSION This study demonstrates that (i) a kidney from an hDAF transgenic pig can support the life of a primate for up to 35 days (and also shows the basic physiological compatibility between the pig and nonhuman primate); (ii) nontransgenic kidneys are not routinely hyperacutely rejected; and (iii) the presence of hDAF on the kidney confers some protection against acute vascular rejection. Improved immunosuppression and immunological monitoring may enable extended survival.
Pyrophosphate, alkaline phosphatase, and vascular calcification.

To the Editor: In their editorial on vascular calcification, Demer and Tintut1 incorrectly state that pyrophosphate reduces calcification by inhibiting alkaline phosphatase. Actually, the opposite is true. Alkaline phosphatase promotes calcification by reducing pyrophosphate levels. Pyrophosphate is a substrate for alkaline phosphatase,2 and …
Regulation of Myelin P0 Glycoprotein Synthesis in Cultured Rat Schwann Cells and Continuous Rat PNS Cell Lines

Abstract: We studied the effects of agents that raise intracellular cyclic AMP on synthesis of myelin components by cultured neonatal rat sciatic nerve Schwann cells and by continuous PNS cell lines derived from the fusion of neonatal rat sciatic nerve Schwann cells with rat RN22 Schwannoma. Treatment with N6,2′‐O‐dibutyryl cyclic AMP (dibutyryl cyclic AMP) caused a fourfold increase in Schwann cell incorporation of 35SO4 into sulfogalactosylceramide (sulfatide), and elicited a 10‐ to 20‐fold increase in such incorporation by the continuous PNS cell lines; a similar effect on PNS cell line sulfatide radiolabelling was obtained with forskolin. Cultured Schwann cells expressed barely detectable levels of myelin P0 glycoprotein (P0) mRNA and myelin basic protein (MBP) mRNA. Treatment of the Schwann cells with axolemmal fragments or with dibutyrylcyclic AMP did not elicit a detectable increase in the levels of these mRNAs. The PNS cell lines constitutively expressed much higher levels of P0 mRNA than did the Schwann cells, and synthesized immunochemically demonstrable P0 glycoprotein, but did not express MBP. Treatment of the PNS cell lines with dibutyryl cyclic AMP markedly reduced expression of P0 mRNA and also diminished immunoreactive P0 glycoprotein. These PNS cell lines should prove useful for further studies of the control of Schwann cell differentiation.
Penetration and binding of L- and D‐carboranylalanine in human melanoma spheroids

The principle of boron neutron capture therapy (BNCT) is that a cell-specific 10B-containing substance binds to tumour cells and irradiation with thermal neutrons is performed when the 10B concentration, In relation to the levels in critical normal tissues, Is at a maximum. Some boron compounds have recently been proposed for BNCT of malignant melanomas; the synthesized L- and o- forms of carboranylalanine and the previously tested compound L-p-boronophenylalanine are candidates. Human melanoma, IGR1, spheroids were used as models of melanoma nodules in this study. The spheroids developed central necrosis when they were about 480 μm in diameter and the volume doubling time was 2.6 ± 0.3 days. The tritiated thymidine labelling index decreased rapidly as a function of distance from the periphery and was, at a depth of 175 μm, close to zero. The penetration patterns showed, for L- and D-carboranylalanine and L-p-boronophenylalanine, a homogeneous distribution of 10B throughout the spheroids by 5 min. L-Carbor-anylalanine gave a more or less even binding of 10B throughout the spheroids and large amounts were present also in the central necrotic regions, D-Carboranylalanine also gave a homogeneous 10B binding in the viable cell layers while the binding in the central necrotic area was lower and a similar, but somewhat lower, binding was found for L-p-boronophenylalanine. Thus, there were no penetration barriers for the boron compounds and binding of 10B was found also in the deeper regions of the viable cell layers. The results showed that the new carboranylalanine compounds are of interest for further analysis, Including toxicological and pharmacological studies in vivo.
Excess vitamin A and development of the cerebral cortex

In previous experiments excess vitamin A, administered to pregnant rats during the early stages of gestation, was found to interfere with the mitotic activity of the neuro‐epithelial cells bordering the neural groove. The result was exencephaly and anencephaly in a high percentage of the newborn. The present work was undertaken to examine the influence of hypervitaminosis A on the behavior of the neuro‐epithelial cells of the cerebral hemisphere and the subsequent migration and differentiation of the neuroblasts during the later stages of development.
Plasma metabolites of dietary flavonoids after combination meal consumption with onion and tofu in humans.

SCOPE The effect of food combination on metabolic profile in postprandial plasma has hardly been reported. We investigated the absorption and metabolism of quercetin and soy isoflavones in humans after combination meal consumption. METHODS AND RESULTS Five healthy volunteers ingested sautéed onion and tofu, and the plasma metabolites of quercetin and isoflavones were analyzed. Quercetin and genistein were incubated with human intestinal Caco-2 cells and human hepatoma HepG2 cells to further analyze the influence of simultaneous supply to the small intestine and the liver. Glucuronosyl conjugates of quercetin and methylated quercetin were the major plasma metabolites in the case of onion intake. Plasma metabolites with the single serving of tofu were both glucuronide and sulfate metabolites of isoflavones. Interestingly, quercetin sulfate was only detected after the combined intake of sautéed onion and tofu, accompanied with a decrease in sulfated isoflavones. Besides, quercetin was shown as the preferential substance for phase II enzymes over genistein in both Caco-2 and HepG2 cells. CONCLUSION These results indicate that, when flavonoids and isoflavonoids were ingested together, the metabolic conversions in the small intestine and/or the liver could be altered, resulting in the variation of the postprandial profiles of the plasma metabolites.
Reliabilität von retrospektiven Berufsverlaufsdaten. Ein Vergleich zwischen dem öffentlichen Dienst und der Privatwirtschaft anhand von Panel-Daten

Im vorliegenden Beitrag wird die Zuverlassigkeit retrospektiver Angaben der Befragten zu beruflichen Tatigkeiten in ihrem Berufsverlauf untersucht. Insbesondere ist ausgehend von einem Befund von De Graaf und Wegener (1989) zu klaren, ob generell Beschaftigte des offentlichen Dienstes ihren Berufsverlauf unzuverlassiger erinnern als Staatsbeschaftigte. Es wird davon ausgegangen, dass gerade Beamte aufgrund der institutionellen Besonderheiten ihrer Beschaftigung grosere Schwierigkeiten haben, ihren Berufsverlauf konsistent zu rekonstruieren als andere Befragte. Empirische Analysen von Panel-Daten erharten diese Vermutung, was die Anzahl der beruflichen Tatigkeiten anbelangt. Jedoch machen Beamte zu anderen Attributen ihres Berufsverlaufs ebenso zuverlassige Angaben wie andere Befragte auch. Diese beamtenspezifischen Erinnerungsprobleme sind bei zukunftigen Erhebungen mittels ereignisorientierter Befragungsinstrumente zu berucksichtigen.
Language Development in Early Childhood: Developmental Changes between the Ages of Three and Four

Language development in toddlerhood and early childhood progresses very quickly, while individual developmental phases are the same irrespective of the language the child is acquiring. The aim of this longitudinal study was to examine the characteristics of children’s language comprehension and expression, and their pragmatic use of language, as well as to determine the developmental language changes that occur between the ages of three and four. The sample involved 80 randomly selected children, 39 girls and 41 boys, whose average age at the fi rst evaluation was 3,1 years and at the second 4,1 years. The research also involved the mothers and teachers of the children included in the sample. The children’s language comprehension and expression were determined using a Language Development Scale, and their pragmatic use of language through testing their storytelling abilities. Their language competence was also evaluated by their teachers and mothers. The results highlight signifi cant differences between threeand four-year-olds as shown by the Language Development Scale and by their storytelling abilities, as well as in the evaluations by their teachers and mothers. Among threeyear-olds, stories at the 2 level of coherence prevailed, i.e. containing simple descriptions of people, objects or illustrations, whereas four-year-olds most often told stories at the 3rd level, i.e. containing a simple temporal stringing together of events. The child’s gender had no signifi cant effect on development between the age of three and four. In interpreting the results, we drew upon the fi ndings of both Slovenian and foreign authors relating to different aspects of language development in toddlers and young children.
Hamonic mitigation of hybrid AC/DC micro-grids with DFIG

The research efforts on micro-grid are increasing rapidly. Hybrid AC/DC micro-grids are one of the most popular topics because of its flexibility and high efficiency. Nonlinear loads on AC micro-grid can deprave the power quality thus the harmonics need to be eliminated. In this paper, the harmonics on AC-side of micro-grids are absorbed and transferred to DC-side of micro-grids through the bi-directional inverter or a novel connected DFIG. The repetitive control is applied. The effects on the DC-side of micro-grid with harmonic elimination by bi-directional inverter and DFIG are discussed. And the final results prove that using the novel connected DFIG in hybrid AC/DC micro-grid for AC-side harmonic compensation can significantly reduce the harmonics that transferred to the DC-side of the micro-grid.
Release activation of iron oxide nanoparticles: (REACTION) A novel environmentally sensitive MRI paradigm

Smart contrast agents for MRI‐based cell tracking would enable the use of MRI methodologies to not only detect the location of cells but also gene expression. Here, we report on a new enzyme/contrast agent paradigm which involves the enzymatic degradation of the polymer coating of magnetic nanoparticles to release encapsulated magnetic cores. Cells were labeled with particles coated with a polymer, which is cleavable by a specific enzyme. This coat restricts the approach of water to the particle, preventing the magnetic core from efficiently relaxing protons. The reactive enzyme was delivered to cells and changes in cellular T2 and T2* relaxation times of ∼ 35% and ∼ 50% were achieved in vitro. Large enhancements of dark contrast volume (240%) and contrast‐to‐noise ratio (48%) within the contrast regions were measured, in vivo, for cells co‐labeled with enzyme and particles. These results warrant exploration of genetic avenues toward achieving release activation of iron oxide nanoparticles. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.