Miracle-dz/UniFAR-FTUs huggingface dataset:
Courbes elliptiques et applications cryptographiques à la diffusion numérique sécurisée

L'objet de cette these est la diffusion numerique securisee realisee a l'aide de courbes elliptiques. Le premier chapitre est consacre au calcul de points de l-torsion sur une courbe elliptique definie sur un corps fini de caracteristique p. Plus precisement, nous combinons un algorithme rapide de calcul d'isogenies du a Bostan, Morain, Salvy et Schost avec l'approche p-adique suivie par Joux et Lercier. Nous obtenons ainsi le premier algorithme valide sans limitation sur l et p dont la complexite est similaire a celle de l'algorithme propose par Bostan et al. Dans le deuxieme chapitre, nous developpons un modele generique de groupes avec couplage qui generalise les modeles presentes auparavant dans la litterature. Nous fournissons un cadre general permettant de prouver dans ce modele les hypotheses cryptographiques reliees au probleme du logarithme discret sur des groupes avec couplage. Dans le troisieme chapitre, nous proposons et etudions un nouveau schema de diffusion pour des recepteurs sans etat. A la difference des schemas s'appuyant sur des techniques de recouvrement par des sous-ensembles definis par des arbres binaires, notre schema considere que l'ensemble des recepteurs destinataires d'un message est decrit par des attributs. La taille du chiffre est lineaire en le nombre d'attributs utilises dans cette description, mais ne depend pas du nombre de destinataires. Par rapport a d'autres schemas bases sur des attributs, le dechiffrement necessite des capacites de calculs bien plus faibles. Le dernier chapitre est consacre a un schema de chiffrement avec tracage de traitres, c'est-a-dire concu pour lutter contre le piratage dans la distribution securisee de contenus vers de nombreux destinataires. Nous proposons un nouveau schema, utilisant des techniques de marquage de contenu, presentant un taux de chiffrement constant et une securite contre des decodeurs pirates puissants. Une particularite de ce schema est la possibilite pour un destinataire de dechiffrer a la volee le contenu transmis.
Stimulation of protein and DNA synthesis in mouse C2C12 satellite cells: Evidence for phospholipase d‐dependent and ‐independent pathways

In C2C12 myoblasts, 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) stimulated a phospholipase D (PLD) to degrade phosphatidylcholine (PC) as measured by the release of choline and an increase in the formation of phosphatidic acid (PA) (or phosphatidylbutanol [PtdBuOH] in the presence of 0.5% butanol). Exogenous PLD also stimulated choline release, PA and PtdBuOH formation. The protein kinase C (PKC) inhibitor, Ro‐31‐8220, and PKC downregulation significantly inhibited the effects of TPA but Ro‐31‐8220 had no effect on PLD action. Neither basic Fibroblast Growth Factor (bFGF) or Epidermal Growth Factor (EGF) increased PLD activity. All agonists stimulated protein synthesis during both a 90 min and a 6 hr incubation and increased RNA accretion after 6 hr. The response at 90 min was not inhibited by the transcription inhibitor, actinomycin D. Ro‐31‐8220 and PKC downregulation significantly inhibited all the effects of TPA. In contrast, Ro‐31‐8220 significantly inhibited the increase in RNA accretion elicited by PLD but had no effect on the ability of agonists other than TPA to enhance protein synthesis. All agonists also stimulated thymidine incorporation into DNA. The effects of EGF, bFGF, and PLD were rapid and transient whereas that of TPA was delayed and sustained. Ro‐31‐8220 and PKC downregulation significantly inhibited the response due to TPA. Furthermore, Ro‐31‐8220 also significantly inhibited the effects elicited by EGF and PLD but not that induced by bFGF. In differentiated myotubes, TPA and PLD, but not bFGF or EGF, again stimulated choline release and PtdBuOH formation. However, all agents failed to stimulate protein synthesis and RNA accretion. The data demonstrate the presence in C2C12 myoblasts, but not differentiated myotubes, of both a PLD‐dependent and PLD‐independent pathway(s) leading to the stimulation of protein synthesis, RNA accretion, and DNA synthesis. © 1995 Wiley‐Liss, Inc.
Absorption of strawberry phytochemicals and antioxidant status changes in humans

In this study the antioxidant composition of fresh and stored strawberries and the bioavailability of the main strawberry bioactive compounds were determined in humans. In addition we have investigated plasma total antioxidant capacity. On 13 healthy volunteers, blood samples were collected before and after acute ingestion of fresh and stored strawberries, 300 g respectively. Ferric Reducing Antioxidant Power (FRAP) values after consumption of fresh and stored strawberries showed a significant increase (P < 0.05) at 5 and 8 hours time interval, while significantly decreased TRAP (Total Radical-Trapping Antioxidant Parameter) values (P < 0.05) were found at 8 hours respect to baseline after stored strawberries consumption. After consuming fresh strawberries, plasma levels of -carotene increased significantly (P < 0.05) respect to stored ones. Moreover, consumption of fresh and stored strawberries resulted in a significant increase of vitamin C at 2, 3 and 5 hours (P < 0.05). The bioavailable amount of strawberries antioxidant compounds reflects the variations observed in fresh and stored fruits. We could summarize that the global food quality is related to both native quantity of bioactive compounds and storage treatments.
A prospective study of alcohol consumption and bone mineral density.

OBJECTIVES--To study the effects of alcohol consumption on bone mineral density in a defined population. DESIGN--Prospective study of bone mineral density, measured during 1988-91, in a cohort who had given baseline data on alcohol intake in the previous week and in the previous 24 hours and other factors affecting bone mineral density during 1973-5. SETTING--Rancho Bernardo, California. SUBJECTS--182 men and 267 women aged 45 and over at baseline, half having been randomly selected and half having been chosen for hyperlipidaemia, who gave baseline information on alcohol intake in one week. Of these subjects, 142 men and 220 women gave information on alcohol intake in 24 hours. MAIN OUTCOME MEASURES--Bone mineral density of the radial shaft, ultradistal wrist, femoral neck, and lumbar spine. RESULTS--Men and women were considered separately, and the tertiles of alcohol consumption were used to delineate low, medium, and high values of alcohol intake. With increasing alcohol intake in one week, bone mineral density (adjusted for age, body mass index, smoking, taking exercise, and oestrogen replacement therapy in women) increased significantly in the femoral neck of men (p < 0.01) and the spine of women (p < 0.01). With increasing alcohol intake in 24 hours, adjusted bone mineral density increased significantly in the radial shaft (p < 0.05) and spine (p < 0.001) of women. Similar, but not significant, patterns were seen at the other bone sites. CONCLUSIONS--Social drinking is associated with higher bone mineral density in men and women.
Modélisation numérique des antennes d’acquisition du signal image en IRM pendant la relaxation

Une technique numerique basee sur le couplage d’une approximation par elements finis et d’une methode integrale a ete developpee pour le calcul du signal induit dans les antennes I.R. M. Ce signal est issu du mouvement de precession libre de l’aimantation transversale du corps a explorer pendant la relaxation. Dans notre modelisation, l’aimantation transversale represente le champ magnetique source. Celui-ci induit dans l’antenne un courant d’une duree tres breve (quelques millisecondes) ; il represente le signal contenant toutes les informations de l’echantillon. Notre modelisation des antennes d’I.R. M de type circuit imprime a ete validee par comparaison avec des mesures experimentales ainsi qu’avec une methode analytique. Nous l’avons developpee en tenant compte de leurs geometries et de leurs caracteristiques electromagnetiques afin d’avoir un meilleur rapport Signal/Bruit. Nous avons pris en consideration des principaux facteurs tels que la distance entre l’antenne et l’echantillon a explorer ainsi que les caracteristiques electromagnetiques de l’antenne.
Thrombosis and Vascular Inflammation in Diabetes: Mechanisms and Potential Therapeutic Targets

Cardiovascular disease remains the main cause of morbidity and mortality in patients with diabetes. The risk of vascular ischemia is increased in this population and outcome following an event is inferior compared to individuals with normal glucose metabolism. The reasons for the adverse vascular profile in diabetes are related to a combination of more extensive atherosclerotic disease coupled with an enhanced thrombotic environment. Long-term measures to halt the accelerated atherosclerotic process in diabetes have only partially addressed vascular pathology, while long-term antithrombotic management remains largely similar to individuals without diabetes. We address in this review the pathophysiological mechanisms responsible for atherosclerosis with special emphasis on diabetes-related pathways. We also cover the enhanced thrombotic milieu, characterized by increased platelet activation, raised activity of procoagulant proteins together with compromised function of the fibrinolytic system. Potential new therapeutic targets to reduce the risk of atherothrombosis in diabetes are explored, including alternative use of existing therapies. Special emphasis is placed on diabetes-specific therapeutic targets that have the potential to reduce vascular risk while keeping an acceptable clinical side effect profile. It is now generally acknowledged that diabetes is not a single clinical entity but a continuum of various stages of the condition with each having a different vascular risk. Therefore, we propose that future therapies aiming to reduce vascular risk in diabetes require a stratified approach with each group having a “stage-specific” vascular management strategy. This “individualized care” in diabetes may prove to be essential to improve vascular outcome in this high risk population.
Power, Empowerment, and Critical Consciousness in Community Collaboration: Lessons from an Advisory Panel for an HIV Awareness Media Campaign for Women

ABSTRACT This study examines the interplay of power, empowerment, and critical consciousness in the dynamics of a public health community collaboration around an HIV prevention media campaign for women. Methodology included a process evaluation consisting of participant observation, focus groups, and one-on-one interviews with advisory board members. Findings suggest that attention to the dynamics of power should begin at the very earliest levels of planning collaborative health projects for women. Additionally, findings indicate that the invisibility of power and privilege affect women's participation in collaborative projects. It is recommended that intentional educational efforts be implemented to help participants in collaborative health projects for women develop the necessary skills and awareness to create an atmosphere of respect and mutuality rather than one of domination and subordination. Education for critical consciousness is suggested as one means for achieving this goal.
A fast information scheduling algorithm for large scale logistics supply chain

Abstract At present, large-scale logistics supply chain information is quickly dispatched, too many constraints are existed. Therefore, a fast information scheduling algorithm for large-scale logistics supply chain based on adaptive genetic optimization is proposed in this paper. The genetic algorithm is used to get the solution and the adaptive technology is brought to solve the congestion problem of genetic algorithm. Experiments show that the proposed algorithm can effectively improve the efficiency of scheduling and solve the existing problems.
A Model of the Differential Representation of Signal Novelty in the Local Field Potentials and Spiking Activity of the Ventrolateral Prefrontal Cortex

Local field potentials (LFPs) and spiking activity reflect different types of information procssing. For example, neurophysiological studies indicate that signal novelty in the ventrolateral prefrontal cortex is differentially represented by LFPs and spiking activity: LFPs habituate to repeated stimulus presentations, whereas spiking activity does not. The neural mechanisms that allow for this differential representation between LFPs and spiking activity are not clear. Here, we model and simulate LFPs and spiking activity of neurons in the ventrolateral prefrontal cortex in order to elucidate potential mechanisms underlying this differential representation. We demonstrate that dynamic negative-feedback loops cause LFPs to habituate in response to repeated presentations of the same stimulus while spiking activity is maintained. This disassociation between LFPs and spiking activity may be a mechanism by which LFPs code stimulus novelty, whereas spiking activity carries abstract information, such as category membership and decision-related activity.
Tourism Promotion of Destination for Swedish Emissive Market

Marketing tools in tourism are constantly changing. The competition in the global tourism market is exponentially growing. Common practice in the tourism sector is the promotion of destination offer to send target audience specific image in correlation with extra destination value. Customizing destination promotional mix to fit global touristic standards ensures efficient destination positioning but includes higher investment. Management of integral parts of the promotional mix is defined with undifferentiated supply and the general image of destination as well as completely opposite terms of the differentiated offer and the general image of the destination. Most of the tourism-related organizations adjust its promotional mix according to values and image they want to present to the target audience. In the same time, there aren’t many tourism organizations, which adjust its promotional mix to different emissive markets. The main research question of this paper is “Does the strategic commitment of a receptive destination offer in terms of managing the marketing mix present strength or weakness? ” The paper will present research results from the survey conducted on tourists from Swedish emissive market in order to define recommendable outlines for the successful promotion of tourism services on the selected emissive market. Given the fact the authors of this paper conducted two parallel primary types of research of attitudes among different samples of the same emissive market (one of them were Swedish tourists who didn’t visit Croatia). Linking of these two aspects has been a research challenge to the expected contribution in the sphere of realizing advisable guidelines for proactive management of destination promotion focused on one emissive market.
Carbon Recycling Through CO2-Conversion for Stepping Toward a Cyclic-C Economy. A Perspective

The conversion of CO2 into added value chemicals, materials and fuels is a case of transition from the linear to the cyclic-C economy, a necessary change for stopping the putative negative effect of CO2 on climate and the environment. Several strategies can be implemented for CO2 conversion and their potential and timeframe is discussed in this perspective paper. The overall amount of avoided CO2 is evaluated in the short-, medium-, and long-term. The distinct contribution of Catalysis, Solar Chemistry and integrated Chemocatalysis-Biosystems is discussed.
A high efficiency non-isolated bidirectional DC-DC converter with zero-voltage-transition

A high efficiency bidirectional dc-dc converter is proposed for energy storage systems. In the proposed bidirectional converter, a simple auxiliary circuit has been applied to provide soft switching at both modes of operation. By added a resonant cell, the converter can realize zero-voltage-transition (ZVT) where both the switch and the rectifier diode achieve soft condition without increasing their voltage and current stresses. The proposed converter has the advantages of simple circuitry, reduced size, low cost and high efficiency because of a single resonant inductor. The operation principle of the converter is analyzed and described. Simulation results of the proposed bidirectional ZVT dc-dc converter are shown to verify its feasibility.
LESSONS LEARNED FROM RESEARCH ON EFFECTS OF COMMUNITY‐BASED LONG‐TERM CARE

Side-effects, drowsiness (n = 2) and ataxia (n = 1), occurred in 3 patients. In two responders, a decrease of the given dosage led to disappearance of the side-effects, and the disturbed behavior did not reappear. In our retrospective analysis, sodium valproate seems to be effective in the treatment of physically aggressive, verbally aggressive, and restless behavior in dementia. Due to the methodological problems (blinding, control group, retrospective classification of the type of disturbed behavior) no definite conclusions can be drawn. However, it is suggested that sodium valproate in a dose of 2 x 240 mg/day might be effective in the treatment of aggressive behavior in dementia.
Individual Animals of a Cattle Herd Infected with the Same Mycobacterium bovis Genotype Shows Important Variations in Bacteriological, Histopathological and Immune Response Parameters

Cattle are the host and main reservoir of the etiologic agent of bovine tuberculosis, Mycobacterium bovis; although other mammalian species, including humans, are susceptible. The tuberculin test and/or slaughterhouse surveillance is the diagnostic method used by control programs all around the world to control and eradicate the disease. In order to compare different tuberculosis diagnostic tests and to reach disease confirmation, a study was performed in a group of 14 steers of Friesian breed, reacting positively to tuberculin test. Three ante‐mortem assays were performed according to the type of sample: the gamma interferon (IFN‐γ) test (which quantifies the release of this cytokine by sensitized lymphocytes in whole blood in response to purified protein derivative (PPD) and recombinant ESAT‐6 and CFP10 proteins); PCR and bacteriologic culture from nasal swab and intradermal tuberculin test. These assays were taken at different times to assess the evolution of clinical parameters. Post‐mortem examination showed macroscopic and microscopic tuberculosis lesions with acid‐fast bacillus and positive cultures. By spoligotyping, we observed that all the isolates showed the same pattern. The positive results based on comparison to lesions observed ranged from 58% to 75% for the IFN‐γ assays, to 72% for cultures, and ranged from 50% to 90% for PCR in nasal swabs. In conclusion, in a herd infected by the same strain, ante‐mortem direct and immune‐diagnostic parameters change, suggesting that several tests are needed for a faster control of infection at herd level.
The role of self-explanation in learning to use a spreadsheet through examples

This papers describes an exploratory study into the early phase of getting to know end-user software during which users make use of a variety of information resources, including the user interface/program itself, manuals, on-line help, examples provided in the manuals and other sources. In particular, how do novices make use of the worked-out examples often provided in manuals and during training? Building on earlier research on the self-explanation effect, thinking aloud data from 10 participants were analysed to see how examples were studied and how they were used during problem solving. Important effects of self-explaining comparable to findings in other domains were found in this study. For instance, those participants who self-explain with the goal to discover meaning prove to be better problem solvers than those who do not self-explain or who focus more on syntactical aspects of examples.
Immunoassay for urinary pyridinoline: The new marker of bone resorption

Urinary pyridinoline (Pyd) and deoxypyridinoline (Dpd) are markers of bone resorption that are elevated above normal in subjects with metabolic bone disease. Total Pyd and Dpd, both free and peptide‐bound forms, can be measured by HPLC after hydrolysis and cellulose chromatography. Since free Pyd is the major component of total Pyd in urine, we developed an immunoassay using free Pyd as an immunogen. This assay is much easier to perform than HPLC, requires no sample preparation, and correlates well with total Pyd measurement by HPLC (r = 0.97) and with urinary hydroxyproline (r = 0.90). The antiserum reacts most strongly with free Pyd and Dpd and minimally with glycosylated and large peptide‐bound forms. The sensitivity of the Pyd immunoassay is less than 25 nM. The intraassay CV is 5–10%; the interassay CV is 10–15%. Analytic recovery studies indicated negligible sample interference. Furthermore, measurement of the Pyd in the same individuals over a 30 day time period exhibited minimal day‐to‐day variation. Thus, the Pyd immunoassay provides a rapid and easy method for evaluation of Pyd in urine. Pyd immunoassay may serve as a practical method of screening for metabolic bone disease and for monitoring therapeutic treatment.
PENGARUH PERIKLANAN DAN KUALITAS PELAYANAN TERHADAP KEPUTUSAN PEMBELIAN SECARA ONLINE PADA SITUS BELANJA ONLINE (Studi Kasus pada Pengguna E-commerce Elevenia Di Kota Semarang)

In Indonesia there are many online marketplace that is place where sellers can create an account and peddling wares. Research results on the website Elevenia shows that a positive and influential advertising significantly to purchasing decision. The influence of advertising and the quality of service to the most influential buying decision is positive and significant. The conclusions of the study of advertising and the quality of service a positive effect against purchasing decisions.
Mammalian Hyaluronan Synthases

Three mammalian hyaluronan (HA) synthase genes, HAS1, HAS2, and HAS3, have been cloned and expressed, allowing the mechanisms for regulation of HA biosynthesis and function to be studied. The hyaluronan synthase (HAS) isoforms differ in kinetic characteristics and product size. The expression of each HAS isoform is controlled in a different fashion when mammalian cells are stimulated by various cytokines and the expression patterns are both spatially and temporally regulated during embryonic development. The existence of three different HAS isoforms with different characteristics implies that the broad range of biological and physiological roles performed by HA are regulated by controlling the activities and expression of the HAS isoforms. This review focuses on recent findings on the regulatory mechanisms for controlling HA biosynthesis and provides new insights into the enzymic basis for the functional regulation of HA.