Miracle-dz/UniFAR-FTUs huggingface dataset:
Evalution Of the Patiens Oral Health Related Quality of Life After Harvesting Free Gingival Graft

Objectives: Oral Health Related Quality of Life is the individual's perception of how oral health affects the quality of life and general health. Periodontal plastic surgery procedures have been reported to negatively affect the quality of life of patients after the operations. The aim of this study was to evaluate the effects of different treatment procedures applied for wound healing of the donor palate site after free gingival graft (FGG) operations on the quality of life. Materials and Methods: After FGG harvesting, 60 patients’ palatal donor sites were randomly assigned one of the six groups, giving 10 participants per group. Palatal wounds were treated with platelet-rich fibrin (PRF), essix retainer, ozone therapy, low-level laser therapy (LLLT) or collagen fleece. As a control group, palatal donor sites were left to secondary healing without any of the treatment procedures. After the postoperative procedures, The Oral Health Impact Profile (OHIP-14) questions were asked to patients to evaluate their quality of life, whereas parameters in relation to postoperative morbidity were analyzed by using Visual Analogue Scale (VAS). Results: Regarding to the questions belonging Turkish version of OHIP-14 (OHIP-14 TR), there were statistically significant relationships between the group categorical variables and the categorical results of question 7 and 10 (p=0.002 and p=0.015). For these questions, the lowest scores were mostly given in the LLLT group. No statistically significant difference was observed between the study groups and total OHIP scores (TOHIP) and the means of 7 subscales of OHIP-14 (p>0.05). Significant differences were found between PRF-ozone groups on the 5th day (p=0.011) for mean VAS scores exhibiting postoperative pain. Conclusions: It has been observed that applying LLLT procedures to the donor wound area following FGG operations may have positive effects on the quality of life and PRF treatments may be more effective in terms of patient comfort after operation.
The Per2 polymorphism rs10462023 is associated with the risk of stroke in a Chinese population

The key clock protein Period2 (Per2) has been suggested to play an essential role in regulating endothelial function. It also regulates the expression of plasminogen activator inhibitor-1, but its role in stroke development has not been studied. To explore the possible association between Per2 and ischemic stroke (IS), 479 Chinese IS patients and 306 healthy controls were recruited, and five tag single nucleotide polymorphisms representing the Per2 locus were genotyped using the Sequenom MassARRAY system. A significant difference was observed in the genotypic distribution (p = 0.014) and allele frequency (p = 0.005) of rs10462023, with carriers of the G allele being more prone to developing IS. After adjusting for possible risk factors including smoking, alcohol use, and history of hypertension and diabetes, a significant association was still apparent. Haplotype analysis also supported the association between Per2 and IS. This study suggests that Per2 variations are associated with IS and may represent genetic risk factors for IS in a Chinese population.
Processed Xanthii fructus increases cell viability of mast cell line, RBL-2H3

The effect of aqueous extract of processed Xanthii fructus (PXF) on cell viability and histamine release from mast cell has been investigated. PXF showed higher cell viability than unprocessed Xanthii fructus (XF) at the concentrations of 5 and 10 mg/ml. Aqueous extract of PXF and unprocessed XF inhibited compound 48/80-induced systemic anaphylaxis in mouse. Both PXF and unprocessed XF dose-dependently inhibited histamine release from rat peritoneal mast cells by compound 48/80 to the similar extent at 0.01, 0.1 and 1 mg/ml. Our studies provide evidence that processing of XF may be beneficial to reduce cytotoxicity in high concentration (at 5 and 10 mg/ml) but does not affect on anti-allergic activity.
DNA Barcoding of Highly Threatened Sacred Plant - Aegle marmelos L.

DNA barcoding is a useful tool to define operational taxonomic units based on standardized DNA regions. In this study, the matK chloroplast gene was tested for species identification of highly threatened sacred plant Aegle marmelos L. , to document their reliable identification, discrimination, similarities and evolutionary trend with their related taxa for future use. DNA isolation from leaf sample of Aegle marmelos was carried out by using a modified Cetyl Trimethyl Ammonium Bromide method (CTAB). Gradient PCR amplification was performed for the isolated DNA using matK gene and the primers, matK472F and matK1248R. Pairwise sequence alignments were made with BLAST and multiple sequence alignments were also made with ClustalW. Based on the sequence alignments, dendrograms were constructed using the software, Mega 5 and Neighbor Joining tree method was used to study the phylogenetic aspects of the species studied and with their related taxa. The success rate of PCR amplification was 90-95% and the success rate of DNA sequence was 95%. The maximum identity of the present study sample was 100% with Aegle marmelos and the similarity of other related species, Severinia buxifolia, Citrus trifoliata and Citrus reticulata was 97% respectively. Accepted: 23 April 2016 Available Online: 06 May 2016
Three essays on quantitative asset pricing

This thesis consists of three separate papers. The ﬁrst paper, “International Diversiﬁcation and the Forward Premium” reproduces the slope of the uncovered interest rate parity (UIP) regression for ten country pairs within one standard deviation under rational expectations. We propose an inﬁnite horizon dy- namic stochastic general equilibrium model with incomplete markets. The underlying mechanism of the model relies on varying international diversiﬁcation in the investors’ portfolio choice decision. This leads to adjustments in interest rates, which are negatively correlated with movements in the exchange rate, as implied by a negative UIP slope. The second paper, “Asset Pricing with Idiosyncratic Risk: The Impact of Job Loss” studies the impact of unemployment risk on risk premia in an incomplete markets economy with many inﬁnitely-lived heterogeneous agents. Job loss is modeled as large, but rare, persistent idiosyncratic shocks with heteroskedastic countercyclical volatility. Within an otherwise standard model and despite conservative assumptions on preferences, we simul- taneously generate a sizeable equity premium and a low risk-free rate. The third paper, “Multivariate Markov Chain Approximations” discusses the problem of discretizing vector autoregressive processes (VAR) into a ﬁnite number of states which is a necessary step to solve equilibrium models numerically. Univariate Markov chain approx- imations are well studied, however, few papers address the multivariate case. This paper presents and compares three approaches to the problem: quadrature, moment matching and bin estimation
A concerted genomic and proteomic approach to understand the early stages of prostate carcinogenesis

Cancer of the prostate (CaP) is the most common cancer in men and the second leading cause of death from cancer. To improve survival rates, an understanding of the molecular events that govern this disease is critical. We approach this goal through a concerted effort to identify the critical, early genomic and proteomic changes that cause the transformation of normal cells into their preand cancerous stages. In the past however, these molecular studies were greatly hindered by the heterogeneity of the tissue and the small size of the early stage lesions. To overcome these problems, a protocol for microdissection of progressionspecific cells from sections of both paraffin-embedded and fresh frozen radical prostatectomy samples that would allow the extraction of high quantity and quality DNA was developed. Further, a standardized protocol for DNA quantitation tailored for these minute microdissected samples was established. Using these protocols, 75 radical prostatectomy specimens were studied. 28 of these specimens (totaling 28 normal, 15 PIN and 30 early invasive carcinoma Gleason grades 2 to 4) yielded sufficient DNA of favorable quantity and quality for SMAL (Scanning of Microdissected Archival Lesions)-PCR fingerprinting. Polymorphic DNA fingerprint fragments correlated with early prostate cancer progression were identified and mapped to lp32, 2p23, 3p26, 4q35, 5q23, 8q22, 8q24, 9q22, llpl3, 12pl2-13, 16ql2, 18q21. Regions of allelic imbalance were reviewed by literature analysis and candidate genes were proposed. As a complementary approach, a working protocol for the use of Laser Capture Microdissection (LCM) coupled with the SELDI ProteinChipTM was also developed and standardized. Using this protocol, a pilot experiment was then conducted by comparing
The research advances of mechanism of pathogenicity of Alternaria phytopathogenic fungi

Until now,about 500 species of Alternaria fungi are discovered,in which more than 95% are facultative parasitism in plants.Alternaria fungi can cause many kinds of plant diseases and make huge loss of agricultural economy.Alternaria fungi carries out facultative parasitism life mainly depending on the following three aspects: damaging the cell walls of their hosts by mechanical penetration and the degrading enzymes,producing mycotoxins that targets at cytoplasmic membrane,mitochondria,chloroplast and influencing the activity of enzymes related metabolisms,and mediating pathogenicity through signal transduction.In this paper,mechanisms of plant pathogenesis caused by Alternaria fungi were reviewed.
Enzyme supplementation improves protein quality of grain legumes for poultry production.

Enzyme supplementation to legume meals has been shown to increase their ME value (Wiiawan et al. 1995) and improve chick performance (Brenes et al. 1993). It is likely that the protein quality of legumes may also be improved by enzyme supplementation. The objective of this study was to determine the protein quality of a range of grain legumes with and without enzyme supplements. An isoenergetic N-free diet and ten isoenergetic legume diets containing nominally 100 g kg -‘protein with and without 1 g kg-l supplementation of a multienzyme product containing xylanase, a -amylase and protease were given to seven-day-old male broilers for 14 days. The treatments were arranged in a 2x10 factorial design with 9 replicates each. The chickens were caged in a temperature-controlled room at 3W 0.5OC and had ad libitum access to feed and water. The chickens were weighed after overnight fasting at the beginning and end of the observation period. Chicken responses were assessed in terms of Net Protein Ratio (NPR), calculated according to Bender and Doell, (1957). The NPR values and the Neutral Detergent Fibre (NDF) content of each grain legume are presented inTable 1. The mean NPR of grain legumes increased significantly (PcO.0 1) after supplementation with a multi enzyme product containing xylanase, cc-amylase and protease. There was a significant (PcO.05) positive correlation (r = 0.64) between percent improvement in NPR values and the cell wall (NDF) content of grain legumes. Generally legumes with a greater cell wall content showed a better response to mixed enzyme supplementation than those with a lower amount of cell wall content.
Antidiarrhoeal activity of Pseudarthria viscida roots.

Aim of study: To evaluate the root extract of Pseudarthria viscida Linn, for antidiarrhoeal activity using standard model. Material and methods: The roots of Pseudarthria viscida Linn were collected from Kolli Hills, dried and extracted with ethanol (95%). Wistar albino rats were used for studies. Castor oil was used to induce diarrhoea and 200, 400 mg/kg of ethanol extract of Pseudarthria viscida (EEPV) was used to test antidiarrhoeal activity. Results were calculated by student " t " test, to assess statistical significance. Results and Discussion: The extract showed dose dependant inhibition of frequency of defecation as well as reduction in number of wet feces. The percentage inhibitions of faecal with 200 and 400 mg/kg doses of ethanol extract were 48.14 and 62.96 respectively. The plant roots extract contains tannins and flavonoids, which could have contribution to the antidiarrhoeal activity. Conclusion: Ethanol extract of Pseudarthria viscida (EEPV) Linn possesses significant antidiarrhoeal activity.
Brand Trust as Mediation Variable of Customer Relationship Management Influence on Student Loyalty

: The purpose of this research is to find out the influence of customer relationship management on student loyalty, customer relationship management on brand trust, brand trust on student loyalty, the role of brand trust in mediating the influence of customer relationship management on student loyalty. This research is an explanatory research. The total sample used in this research is 110. The sampling technique used is purposive sampling. The questionnaire is used as a tool to collect data. The research tool used is Smart PLS. From the test result using Smart PLS, it can be concluded that customer relationship management significantly influences student loyalty, customer relationship management significantly influences brand trust, brand trust significantly influences student loyalty, and brand trust partially mediates the influence of customer relationship management on student loyalty.
Synthesis of GR 125487, a selective 5-HT4 receptor antagonist

ABSTRACT The 5-HT4 receptor (5-HT4R) agonists are important in treating gastrointestinal motility disorders. Their role is currently being evaluated for the treatment of cognitive and mood disorders. A selective 5-HT4R antagonist GR 125487 is used in many biological assays to cross confirm the 5-HT4R agonist’s activity. A practical synthesis of GR 125487 is developed so as to have it in desired quantities. The synthesis consists of seven steps starting from commercially available methyl 5-fluoroindole 3-carboxylate. The GR 125487 thus synthesized was used in blocking the activity of 5-HT4R agonist compound in animal models of cognition. GRAPHICAL ABSTRACT
Availability and inequality in accessibility of health centre-based primary healthcare in Ethiopia

Background Achieving fair access to healthcare and improving population health are crucial in all settings. Properly staffed and fairly distributed primary health care (PHC) facilities are prerequisites to ensure accessible healthcare services. Nevertheless, availability and accessibility issues are common public health concerns, especially in under-resourced countries including Ethiopia. Measuring inequalities in accessibility of healthcare resources guide policy decisions to improve PHC services and ultimately achieving universal health coverage (UHC). Purpose To assess availability and measure magnitude and trend of inequalities in accessibility of health centre-based PHC resources in Ethiopia during 2015 to 2017. Methods We conducted a cross-sectional population-based analysis of district-level data collected from 16th December 2017 until 24th May 2018. Afar, Dire-Dawa, and Tigray regions were purposefully included in the study to represent the four pastoralist/semi-pastoralist, three urban and four agrarian regions in Ethiopia, respectively. We used ratios, different inequality indices and Gini decomposition techniques to characterise the inequalities. Results In 2017, median of health centres (HCs) per 15,000 inhabitants and their Gini indices (GIs) for Afar, Dire-Dawa, and Tigray were 0.781, 0.566, 0.591 vs. 0.237, 0.280, 0.216 respectively. Median overall skilled health workers (SHWs) per 10,000 inhabitants were 5.250, 7.539, and 6.246, respectively. These accounted for 11.80%, 16.94% and 14.04% of the WHO target of 44.5 to achieve SDGs. The corresponding GIs for the regions were 0.347, 0.186 and 0.175. Despite a higher overall SHWs inequality in the urban districts of Tigray (GI = 0.301), only Tigray showed significant inequality reductions in GHE (p < 0.001) and in all categories of SHWs (p < 0.05). Conclusions Our analysis provided a clear picture of availability and inequalities in PHC resources across three regions in Ethiopia. Identifying contributing factors to low densities and high inequalities of SHWs may help improve PHC services nationwide, along with pathway towards UHC.
Survey on the Overwintering of Syrphids in Changbai Mountains and Experiments on Artificial Protection of the Overwintering Syrphid Flies

In Changbai Mountains, there are about 130 days each year with an average temperature below zero. The ground is covered with snow for about 100 days each year and the lowest temperature could be as low as –35 C during winter. Under natural conditions, Paragus quadrifasciatus in the form of pupae overwinters in soil 4 centimeters beneath the surface. In the following year, these overwintering pupae hatch from mid-April to early May. Observations at fixed points in 4 different types of soil (sandy soil, black soil, southern hillside and northern hillside) were carried out continuously from 1988 to 1990 for three years. About 500 pupae of P. quadrifasciatus were released and protected at each point in late October. These points were covered with nets on April 15 of the following year and observed for the number of adult eclosion at an interval of 3 days. If the non-eclosion pupae were still alive on May 10, they were counted as eclosion pupae. The observed results are listed in Table 1.
Population analysis of Saurida tumbil in the Northern South China Sea

Since fish population is a basic unit of study and management of fishery resources,analysis of fish population is a foundation for biological and ecological study on fish reproduction,distribution and migration. Using molecular biology method,the paper analyzed population of Saurida tumbil,an important commercial species from northern continental shelf waters of South China Sea. A total of 78 samples of Saurida tumbil were collected from Beihai,Zhanjiang,Maoming,Dongguan,and Shanwei of northern South China Sea. We found there are 48 haplotypes and 39 variation sites in 568 bp gene fragments of 78 sequences obtained by sequencing the mitochondrial D-loop of the samples. Analysis of molecular variance( AMOVA) indicates that the genetic variability within groups is 98. 82% and that among groups is only 1. 18% . The genetic differential index( Fst) and the genetic distance between every two groups are 0. 000 24 - 0. 030 08 and 0 -0. 025,respectively. Molecular tree constructed by NJ method and the network constructed by TCS1. 21 show that the individuals of different groups are not clustered as one independent group and intermixed together,which indicates that there clearly exists a great gene flow among groups,and the genetic diversities among groups are at quite lower levels. According to the criteria distinguishing different populations,species and genera given by scholars Theorpe and Shaklle,the five groups should be merged to the same population. However,Saurida tumbil population built its geological groups by means of continuously rapid growth in small ones after undergoing fast expansion,differentiation and bottleneck phase,which not only accords with the traditional viewpoint of basic characteristics of fishery resources of South China Sea to a certain extent— "The populations of most species belong to local population without a long-distance migration",but also is regarded as an evidence of molecular biology.
Design of experiments to estimate offspring-parent regression using selected parents

Heritability or the genetic regression of one trait on another, for example live-weight gain in field v. performance test station conditions, can be estimated efficiently by rearing offspring only from high- and low-ranking individuals, and estimating the regression of offspring on parent performance. Formulae are given for the optimum proportion of available animals to select as parents when the relative numbers of individuals in the parent and progeny generation are fixed. Although the optimum depends on the value of the parameter to be estimated, the designs are very robust to poor estimates.
Incidence du génotype du gène du récepteur à la ryanodine (Ryr1) associé à la sensibilité au stress dans 5 filières porcines belges

Le syndrome de stress chez le porc est dû à une mutation ponctuelle au niveau du gène Ryr1 codant pour le récepteur à la ryanodine. Ce syndrome se manifeste par une mortalité suite à des conditions de stress ou par une viande de mauvaise qualité. Nous avons détecté le génotype de cette mutation chez 505 individus pris dans 5 filières porcines belges. Ce génotypage a été réalisé par Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) ou par PCR en temps réel. Les résultats indiquent que 22,4 % des porcs sont sensibles au stress (génotype TT) et que 77,6 % des porcs sont résistants (63,4 % de génotype hétérozygote CT et 14,2 % de génotype CC). Une étude statistique permet de séparer les filières en deux groupes : les filières 1 et 2 présentent un taux élevé en individus TT (44 % et 52 % respectivement) alors que les filières 3, 4 et 5 présentent un taux élevé d’individus hétérozygotes (74 %, 92 % et 72 % respectivement).
Sex Does Not Affect Early Growth or Survival in Chicks of the Roseate Tern

-We sexed 327 Roseate Tern chicks (Sterna dougallii) at hatching and measured their growth during the first three days of life. These data on early growth predict their survival to fledging with high confidence (97% for A-chicks and 83% for B-chicks), using a discriminant function derived in an earlier study. After controlling for other factors, there was no evidence that early growth or survival differed between males and females. This finding in a sexually monomorphic species is consistent with the hypothesis that the sex-biased chick mortality observed in sexually dimorphic species results from differential costs in chick-raising. Received 15 September 2000, accepted 10 October 2000.
Identification of a Lactic Acid Bacteria Strain Rich in Surface(S)-Layer Protein and Its Tolerance to Digestive Enzymes

A strain of lactic acid bacteria was isolated from fresh milk by plate streaking method.The isolated strain was named as M8,which was rich in S-layer protein according to sodium dodecyl sulfonate polyacrylamide gel electrophoresis(SDS-PAGE) analysis.The strain was identified as the species of Lactobacillus brevis via morphological observation,physiological and biochemical characteristics,and phylogenetic analysis of 16S rRNA sequences.Its excellent tolerance was found during sequential suspension at 37 ℃ in a mimic gastric juice(pH 2.5) containing pepsin(3 g/L) and citric acid-phosphate buffer(100 mmol/L) and then in a mimic small intestinal juice(pH 8.0) containing trypsin(10 g/L) and Tris-HCl buffer(25 mmol/L). Therefore,S-layer protein may function as a protective barrier and resist the invasion of digestive enzymes.