Miracle-dz/UniFAR-FTUs huggingface dataset:
Neuro-Engineering : from neural interfaces to biological computers

In this chapter, we report on the state of the art in the technology of neural interfaces, and describe in some detail a number of on-going projects, in which they are used to explore the neurobiology of learning and memory. In particular, it is proposed to use artificial multi-sensory information coming from a roving robot that interacts with the environment, under the perspective of feeding an in vitro network of real neurons with a set of time and spacedependent signal resembling those processed by the nervous system.
CONVEX-BODIES, ECONOMIC CAP COVERINGS, RANDOM POLYTOPES

Let K be a convex compact body with nonempty interior in the d-dimensional Euclidean space Rd and let x1, …, xn be random points in K, independently and uniformly distributed. Define Kn = conv {x1, …, xn}. Our main concern in this paper will be the behaviour of the deviation of vol Kn from vol K as a function of n, more precisely, the expectation of the random variable vol (K\Kn). We denote this expectation by E (K, n).
ERGONOMIA NO TRANSPORTE DO MATERIAL ESCOLAR NO ENSINO FUNDAMENTAL

Objetivo: avaliar o peso e o modo de transporte de mochilas e os desconfortos relatados pelos alunos. Metodo: Estudo transversal realizado em Novembro e Dezembro de 2015 utilizando questionarios, pesagem de 411 estudantes e do material escolar. Resultados: Houve um aumento com a idade e sexo masculino em transportar mochila com alca dupla e com peso mais adequado. Utilizar mochilas com uma alca, transporte publico ou ir a escola a pe, com maior tempo de deslocamento e a percepcao de peso da mochila associou-se a referencia de dor nas costas. Conclusao: Estudantes mais velhos e masculinos carregam mochilas transportando material mais adequadamente. Foram associados a referencia de dor nas costas a percepcao de peso da mochila, o modelo e o modo de utiliza-las, o meio e o tempo de locomocao. ERGONOMICS IN THE TRANSPORT OF SCHOOL MATERIAL IN PRIMARY EDUCATION Objective: to evaluate the weight and mode of transportation of school supplies and discomforts reported by students. Method: Cross-sectional study carried out in November and December 2015 using questionnaires, weighing 411 students and school material. Results: There was an increase with age and male gender in carrying backpack with double handle and with more suitable Older students and male students use the backpack with more suitable weight. Using backpacks with a handle, public transportation or going to school on foot, with longer travel time and the weight perception of the backpack associated with greater reference to back pain. Conclusion: Older and male students carry backpacks carrying material more properly. The perception of backpack weight, the model and the way of using it, the means and the time of locomotion were associated with the reference of back pain.
Osteoporozda Güncel Tedavi

Osteoporosis is a progressive bone disease that is characterized by decrease in bone mass and density, distortion of bone microstructure and increased fracture risk. It affects millions of people mainly post-menopausal women and has high socio-economic burden. Osteoporosis decreases quality of life, increase mortality and morbidty. Here we will focus on the recent guidelines of osteoporosis and summarize the therapeutic options.
Perceive-Sleeve : Towards Personalized Tactile Feedback on Interactive Surfaces

Tactile feedback on interactive surfaces such as touchscreens provides significant benefits in terms of reducing error-rates, enhancing interaction-speed and minimizing visual distraction [2]. Research about tactile feedback on direct-touchsurfaces can be categorized as follows: First, mobile actuator systems like the one used by Kaaresoja et al. [6] move the mobile device or the device’s screen as a whole using motors or piezoelectric actuators. With this approach only a single touch-input can be augmented haptically. Second, shape displays, such as FEELEX [5] or Lumen [8] are based on the segmentation of the interactive surface into individually movable ‘haptic pixels’. Currently, these systems only provide a small number of actuated points due to mechanical constraints. All these approaches share the assumption that haptic feedback has to be given at the location of the interaction. We propose spatially disuniting the bodypart of interaction (hand, finger) and the resulting tactile feedback. In other words: while the user explores a virtual element on the interactive surface Copyright is held by the author/owner(s). Hendrik Richter University of Munich
Une Aalyse Comparative des Systèmes de Gouvernance des Firmes et des Coopératives

The System of Cooperative Governance: a Comparative Analysis When financial scandals have erupted some large firms in recent years, people start questioning the system of governance. However, the debate that followed has ignored -to some extentthe model of cooperative companies. In this study, we present a comparative analysis of these two models. We bring into surface and discuss the prevailing assumption of the reliability of the governance system of cooperative structures in mitigating conflicts of interest related to capitalist firms. It is then pertinent to review the organizational structure of cooperatives in order to highlight its specificities and focusing on how to manage differences of interests. To this end, we first consider the conceptual framework of governance and its specificity in the case of cooperatives. But before this we will present the functioning of the cooperative structure and the game of interest behind this structure, as opposed to the private firm. Finally, we deduce the consequences of Une analyse comparative des systèmes de gouvernance . 65 this specificity in terms of management and more specifically on entrepreneurship in the two organizational models
Knock-out of Glial Channel Acd-1 Exacerbates Sensory Deficits in a C. Elegans Mutant By

26 DEG/ENaC channels are voltage-independent Na or Na/Ca channels expressed in many 27 tissues and needed for a wide range of physiological functions, including sensory perception 28 and transepithelial Na transport. In the nervous system DEG/ENaCs are expressed both in 29 neurons and glia. However, the role of glial versus neuronal DEG/ENaCs remains unclear. We 30 recently reported the characterization of a novel DEG/ENaC in Caenorhabditis elegans that we 31 named ACD-1. ACD-1 is expressed in glial amphid sheath cells. The glial ACD-1 together with 32 the neuronal DEG/ENaC DEG-1 are necessary for acid avoidance and attraction to lysine. We 33 report here that knock-out of acd-1 in glia exacerbates sensory deficits caused by another 34 mutant: the hypomorphic allele of the cGMP-gated channel subunit tax-2. Furthermore, sensory 35 deficits caused by mutations in Gi protein odr-3 and guanylate cyclase daf-11, that regulate the 36 activity of TAX-2/TAX-4 channels, are worsened by knock-out of acd-1. We also show that 37 sensory neurons of acd-1 tax-2(p694) double mutants fail to undergo changes in intracellular 38 Ca when animals are exposed to low concentrations of attractant. Finally, we show that 39 exogenous expression of TRPV1 in sensory neurons and exposure to capsaicin rescue sensory 40 deficits of acd-1 tax-2(p694) mutants, suggesting that sensory deficits of these mutants are 41 bypassed by increasing neuronal excitability. Our data suggest a role of glial DEG/ENaC 42 channel ACD-1 in supporting neuronal activity. 43 44
Design de interação: além do alcance individual

Interaction design is a design of the subarea that has sought to reduce the negative aspects of the experience of people using a product and at the same time improving its positive aspects (Rogers, 2013). This study aims to present the concepts, applications and support of universal design to show how interaction design can contribute to an equal extent, where people with different profiles and limitations can use the same device, with a good user experience. We will address the concept of social innovation and inclusion in the digital world and present some practical applications in the field of Human-Computer Interaction as software and games.
On Refining Partitions

3. A lower bound To obtain a lower bound we count only those sequences of refinements which include the partition 1 . 2.3 . d . r of n into d or d + 1 parts, d of which are of different size, where 0 < r = n-$d(d + 1) < d, so that J(2n) > d > J(2n)-3. Moreover we only count sequences in which we split off 1 from each of the d 1 parts of different size greater than 1. These d 1 steps can be made in (d l ) ! ways and result in the partition ldf 2 . 3 . (d 1) . r of n into 2d 1 or 2d parts, d 1 (or possibly d ) of which are of different size. We deal with this in the same way, making splits of size 1 from each of the d-2 parts of different size greater than 1, in (d-2)! possible ways. If we continue, we see that the number of sequences of refinements is at least
Antiagregantes plaquetários: ampliando conhecimento

O objetivo nesta revisao da literatura foi obter um maior conhecimento sobre os medicamentos antiagregantesplaquetarios, perpassando sobre mecanismo de acao, as formas de tratamento e os problemas relacionados a eles. O farmaceutico inserido no contexto da multidisciplinaridade coloca em pratica a atencao farmaceutica. Nas doencas tromboembolicas suas acoes perpassam desde a profilaxia, tratamento e nos problemas relacionados aos medicamentos, assim contribuindo para melhora da qualidade de vida dos pacientes.
Preface What is Software Change Impact Analysis ?

Software change impact analysis, or impact analysis for short, estimates what will be affected in software and related documentation if a proposed software change is made. Impact-analysis information can be used for planning changes, making changes, accommodating certain types of software changes, and tracing through the effects of changes. Impact analysis provides visibility into the potential effects of changes before the changes are implemented. This can make it easier to perform changes more accurately.
Qualitative analysis of one- or two-species neutral delay population models

In this paper neutral delay models of single population growth, predator-prey, and competition interactions are introduced and investigated. These systems are more general than previous ones by allowing per capita growth rates to be nonlinear and delays to be of the general distributed type. Conditions are given for solutions of these systems to be bounded for proper initial functions. For neutral delay single population models, sufficient conditions for solutions tending to the positive-steady states are also presented.
Punctuated equilibria ( evolutionary theory )

The term “punctuated equilibria” refers to Stephen Jay Gould and Niles Eldredge's 1972 proposal regarding the nature of biological data as preserved in the fossil record and the implications that those data have for evolutionary theory. Eldredge and Gould proposed that the history of life was not characterized by morphologically “connecting together all the extinct and existing forms of life by the finest of graduated steps,” as hypothesized by Darwin in 1859 and subsequently portrayed by mid-twentieth-century textbooks (Fig. 1). Rather, Gould and Eldredge envisioned evolutionary history as a network characterized by long periods of morphologic stability (stasis mode) punctuated here and there by rapid events of speciation (punctuation mode) [Fig. 2]. When first proposed, the concept of punctuated equilibria caused considerable controversy because aspects of the punctuated-mode pattern were promoted as falsifying some long-held beliefs about Neo-Darwinian evolutionary theory—termed “phyletic gradualism” by Gould and Eldredge. Later, punctuated equilibria also came to be used by creationists (incorrectly) to throw doubt on the entire theory of evolution. Today, the punctuated equilibria model is regarded as a valid characterization of a number of fossil lineages, but is no longer regarded as challenging contemporary evolutionary theory.
OPTIMAL PULSE SHAPES FOR PERIODIC REVERSE ELECTROPLATING

Abstract – In this report, time-dependent carrier concentration in electrolytic cells, due to some basic periodic shapes of excitation signal, has been studied. Exact analytical solutions for step, sinusoidal and periodic pulse reverse inputs are derived. The effect of frequency, forward and reverse amplitudes, and duty cycle are investigated. An analytical solution of the model is obtained as Fourier series using Laplace transformations applied to a onedimensional model with linearized Butler-Volmer electrode kinetics. The results are applied to an acid-copper bath. It is shown that optimal operation points exist. Optimal current waveforms for obtaining efficient and enhanced deposition process, and faster deposition rate compared to simple DC electroplating is discussed.
A property of power series with positive coefficients

The following theorem is suggested by a problem in the theory of probability . ' Let pk be a sequence of non-negative numbers for which Eó pk =1, and let m = Ei kpk <_ "0. Suppose further that P(x) _ E p kx k 0 is not a power series in xl for any integer t > 1. Then 1-P(x) has no zeros in the circle I x I < 1, and the series U(x) _ u • k x k 1-P(x) 0 has the property lim u n = 1/m. n-(If m= oo, we define 1/m to be zero .) We shall first give a proof in case m <-. The method used is not elementary, but yields somewhat more information than stated in the theorem. Later in this paper an elementary proof is given, valid for both m<-and m =-. We suppose that m < o o. Let rn = pk, R(x) _ r n xn. k=n+1 0 Then m = E0 rk and (2) 1-P(x) _ (1-x)R(x). Since m < oo the power series for R(x) converges absolutely and uniformly in I x I <=1. We claim that R(x) has no zeros for I x I <=1. For I xI < 1 this is clear from (2), since P(x) has positive coefficients Received by the editors March 1, 1948. 1 To be published elsewhere. The theorem and method of the present paper were extended to the continuous case by D. Blackwell, A renewal theorem, Duke Math .
qu an tph ] 2 M ar 2 01 8 Quantum Circuit Learning

We propose a classical-quantum hybrid algorithm for machine learning on near-term quantum processors, which we call quantum circuit learning. A quantum circuit driven by our framework learns a given task by tuning parameters implemented on it. The iterative optimization of the parameters allows us to circumvent the high-depth circuit. Theoretical investigation shows that a quantum circuit can approximate nonlinear functions, which is further confirmed by numerical simulations. Hybridizing a low-depth quantum circuit and a classical computer for machine learning, the proposed framework paves the way toward applications of near-term quantum devices for quantum machine learning.
Title: Blockinground Blockintruthing Blockintip-dating Blockinmethods Blockinusing Blockinfossil Blockincanidae Blockinreveals Blockinmajor

21 . CC-BY-NC-ND 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not . http://dx.doi. org/10.1101/049643 doi: bioRxiv preprint first posted online Apr. 21, 2016;
Editorial: Customizing sarcoma management and treatment.

DOI:10.1097/CCO.0000000000000551 Sarcomas and aggressive connective tissue tumours represent a large family of heterogeneous mesenchymal malignancies, with over 80 histological subtypes in the 2013 WHO classification [1]. This histological classification, progressively evolving and complexifying, is completed with a histological three-grading system applied to only a subset of these tumours, a molecular classification that not only includes genomic rearrangements (translocations, mutations, amplification, tumour suppressor gene loss and so on) but also expression profiling (such as the CINSARC molecular grading) [2,3]. Altogether, sarcomas are very rare diseases with an overall incidence of 5.9/100 000/year in adults, representing 1–2% of all cancers in adults, 15% of children cancers and therefore a highly fragmented group of disease, with a wide variety of clinical presentations and natural histories. In contrast to this fragmented landscape, the management of sarcoma patients in localized phase is remarkably homogenous, requiring an initial biopsy with histological review in a reference centre, en-bloc surgical removal by an expert team, preceded or followed by radiotherapy for large and or grade 2 and 3 tumours. Neoadjuvant and adjuvant chemotherapy for large and/or high-grade tumours is debated in clinical practice guidelines, and recommended by some expert centres for selected patients [2,3]. In advanced phase, the guidelines are conversely becoming increasingly more complex, with dedicated systemic treatments, approved cytotoxics (doxorubicin, ifosfamide, DTIC, trabectedine, eribuline), cytotoxics not approved for sarcoma (gemcitabine, docetaxel, paclitaxel and so on) or targeted treatments (imatinib, sunitinib, regorafenib, pazopanib, crizotinib, everolimus, denosumab) in different therapeutic lines reserved for certain histological and or molecular subtypes [4]. In this context, it is of course necessary to drop the one-size-fits-all approach for sarcoma management, which was used years ago to adopt therapeutic strategies not only based on histotypes and molecular subtypes but also on anatomical subtypes. In this issue of Current Opinion in Oncology, a series of articles describe the state-of-the-art of sarcoma management in localized and advanced
Information Retrieval for E-Discovery

E-discovery refers generally to the process by which one party (for example, the plaintiff) is entitled to discover evidence in the form of electronically stored information that is held by another party (for example, the defendant), and that is relevant to some matter that is the subject of civil litigation (that is, what is commonly called a "lawsuit"). Information Retrieval for E-Discovery describes the emergence of the field, identifies the information retrieval issues that arise, reviews the work to date on this topic, and summarizes major open issues. Information Retrieval for E-Discovery is an ideal primer for anyone with an interest in e-discovery; be it researchers who first practiced law but now study information retrieval, or those who studied information retrieval but now practice law.
Advancing Early Identification of Axial Spondyloarthritis: An Interobserver Comparison of Extended Role Practitioners and Rheumatologists

Objective. To compare clinical impression and confidence of extended role practitioners (ERP) with those of rheumatologists experienced in axial spondyloarthritis (axSpA) according to (1) evaluation of patients with chronic back pain assessed for axSpA; and (2) magnetic resonance imaging (MRI) recommendation for further investigation of these patients. Methods. Patients with ≥ 3 months of back pain and age of onset < 45 years were referred for axSpA evaluation. An ERP assessed consecutive patients and recorded standardized clinical information in written form. Three rheumatologists subsequently evaluated each patient based on the recorded information. Patients were classified as having axSpA or mechanical back pain based on clinical and investigative findings. Level of confidence was noted for classification and MRI indication. Agreement between assessors was evaluated using percentage agreement and κ coefficient. Results. Fifty-seven patients were assessed. Interobserver agreement of clinical impression for all raters was moderate (κ = 0.52). Agreement of clinical impression between ERP and rheumatologists ranged between 71.2% (κ = 0.41) and 79.7% (κ = 0.57). Agreement of clinical impression among rheumatologists ranged from 74.1% (κ = 0.49) to 79.7% (κ = 0.58). All rater agreement for MRI indication was fair (κ = 0.37). ERP agreement with rheumatologist for MRI recommendation ranged from 64.2% (κ = 0.32) to 75% (κ = 0.48). Agreement for MRI indication among rheumatologists ranged from 62.9% (κ = 0.27) to 74% (κ = 0.47). Confidence in clinical impression was similar among all practitioners. Conclusion. ERP with specialty training in inflammatory arthritis demonstrate clinical impressions comparable with those of rheumatologists in the assessment of axSpA. Incorporation of such roles into existing models of care may assist in early detection of axSpA.
Biological Control of Phytopathogen Microorganisms with Antagonist Bacteria

Amalia Gheorghe, Luiza Jecu, Anca Voicu, Florina Popea, Andreea Rosu, Anca Roseanu 1 National Research and Development Institute for Chemistry and PetrochemistryICECHIM, Spl. Independentei 202, Bucharest, Romania, tel/fax 004-021.316. 30.63, amalia_ghe@yahoo.com. 2 Institute of Biology Romanian Academy, Spl. Independentei 296, Bucharest, Romania, tel/fax: 004-021.221. 92.02/004-021.221. 90.71, anca.voicu@ibiol.ro. 3 Institute of Biochemistry Romanian Academy, Spl. Independentei 296, Bucharest, Romania, tel/fax: 004-021.223. 90.69/004-021.223. 90.68roseanu@biochim.ro.
Öòòòòó Äðóôô×¸âó× Äº Îó¸òò Òøóòòó Ööö Òòòþ Öùôó Òú×øøøøøøø Óò Ò Èöó××ñññòøó Ð Ääòòùù Ý Ë×øøññ× Áòòóöñññññ Óò Ôôöøøññòøó Ääòòùù× Ý Ëë×øøññ× Áòòóöññ Øøøó× Íòòúö××øý Ó Ð Ò Øø¸ëôôôò

Passage Retrieval is an alternative to traditional documentoriented Information Retrieval. These systems use contiguous text fragments (or passages), instead of full documents, as basic unit of information. IR-n system is a passage retrieval system that uses groups of contiguous sentences as unit of information. This paper reports on experiments with IR-n system at Clef-2002 where it has obtained considerably better results than last participation.
Design of a New Dodecyl Sulfate-Selective Electrode Based on Conductive Polyaniline

A new, simple, sensitive, low cost and rapid potentiometric method for direct determination of ultra trace amounts of sodium dodecyl sulfate (SDS) with a new DS^–-selective electrode is reported. The electrode was prepared by electropolymerization of aniline in acidified DS^– ion on the surface of a Pt electrode. The cyclic voltammetry (CV) was used for electropolymerization of polyaniline (PA) in the potential range of–200 to +1000 mV vs . Ag/AgCl. This sensor showed a Nernstian behavior (59.0 ± 2.3 mV/decade) over a very wide linear range (1.0 × 10^–9–3.0 × 10^–6 M) with a detection limit of 1.0 × 10^–9 M. The response time of the electrode was 15 s for 1.0 × 10^–7 M of analyte; the electrode can be used for 4 weeks without any major deviation. This electrode can be used in the pH range of 3.5–9.8. The selectivity of electrode to DS^– over some organic, inorganic and anionic surfactants was investigated with the fixed primary ion method. The results show that the electrode is highly selective to DS^– ion over other ions. The proposed electrode was applied to the determination of DS^– in real samples.