Miracle-dz/UniFAR-FTUs huggingface dataset:
Suprapubic Liposuction With a Modified Devine’s Technique for Buried Penis Release in Adults

Background: With the increasing prevalence of overweight and obesity, adult-acquired buried penis is more common in recent years. Many surgical techniques have been reported. However, none is the gold standard. Objective: To evaluate the safety and efficacy of combining suprapubic liposuction and modified Devine’s technique for penile lengthening in adult patients with buried penis due to obesity Methods: From September 2015 to June 2018, 26 consecutive suitable patients (mean age: 33 ± 5.7 years, mean body mass index: 29 ± 5.4 kg/m2) with a buried penis received suprapubic liposuction and modified Devine’s technique for penis release in our medical centre. A retrospective study was conducted. Their penile length from tip to the skin (flaccid) was measured pre- and post-operatively. The amount of liposuction was also recorded accordingly. Results: The mean length of the follow-up on the 26 patients is 18 ± 7.1 months (range 3-33 months). The average amount of liposuction is 450 ± 90.2 mL. The average penile length measured preoperatively, post-operatively (on table), and 3 months after the operation is 2.9 ± 1.3, 7.4 ± 2.1, and 5.3 ± 1.8 cm, respectively. The post-operative penile length had significantly increased by 4.5 ± 1.6 cm (on table) and 2.4 ± 0.7 cm (3 months post-operation) with a P value <. 05. No patient had difficulties in sexual intercourse or urination post-operatively. None of the patients were dissatisfied with their surgical outcomes. Conclusions: The combination of suprapubic liposuction and modified Devine’s technique is a safe and effective method for releasing the buried penis of adults with satisfying outcomes.
Fisheries eco-biology of beel Koshba in Naogaon District

The physical conditions of Beel Koshba consisting of water temperature (25.36±5.12°C/day), water depth (204.96±110.36cm/month) and water transparency (30.91±6.78 cm/day) were recorded. The chemical parameters of total hardness, alkalinity, pH, DO, CO 2 and ammonia were 146.60±13.36 mg/l, 143.30±9.33 mg/l, 7.05±0.75, 6.03±1.08 mg/l, 8.64±0.88 mg/l and 0.73±0.31 mg/l respectively. A total of 54 species of different vegetations 123 species of phytoplankton and 73 species of zooplankton were recorded from the beel. A total of 104 species of fish and Annelids (8), arthropods (12), molluscs (15), amphibian (8), reptiles (21), avis (40) and mammals (12) were identified. Pesticidal toxic effluents contexts were also observed in the beel ecosystem. Key words: Fisheries; Eco-Biology; Beel Koshba DOI: 10.3329/ujzru.v28i0. 5283 Univ. j. zool. Rajshahi Univ. Vol. 28, 2010 pp. 33-39
Use of Information and Communication Technologies in the Inclusive Process of Educational Institutions

The article substantiates the relevance of the problem of using information and communication technologies (ICT) to partially solve the problem of accessibility to education for certain categories of people with disabilities and improving the quality of educational services. Theneed for introducing open access repositories with educational and scientific content is emphasized, which will allow alternative ways of gaining knowledge despite time or space constraints. The advantages and disadvantages of using ICT in the inclusive process are outlined, and their main types are proposed which can be used to support inclusive education. The features of creating an effective computer-integrated learning environment in the inclusive process are identified, forms and methods of working with children with special needs using ICT are presented. The authors display the results of a survey of teachers regarding their attitude to this problem and their professional skills in using ICT in the educational process of a general secondary educational institution. The article focuses on the necessity to study and promote assistive technologies in inclusive learning, which are developed today in the world to enable people with disabilities to get education and their social integration. These technologies give people the opportunity to learn effectively, receive new information, communicate through devices to control computer equipment, including remotely; reading electrical signals, etc. The difficulties of implementing ICT in inclusive education of Ukraine are substantiated, among them: high cost of ICT, especially assistive technologies; lack of computer software at educational institutions, lack of powerful internet, especially in rural areas; low level of digital literacy of teachers, especially regarding the use of special training tools; often their conservative attitude to innovations, online communication with students with special educational needs; the lack of support for such students as for the use of specialized ICTs and others.
Why Don't More Hummingbird-Pollinated Flowers Have Dark-Colored Pollen?

This note derives from work done during an NSF predoctoral fellowship at the University of California, Santa Barbara (UCSB). Computer support was provided by the UCSB Department of Biological Sciences, an NIH/NIMH grant to the UCSB Computer Center, a Ford Foundation grant to the UCSB population biology program, and a computer grant from the University of Maryland. Comments from B. Bradley, M. O'Neill, and anonymous reviewers improved the manuscript.
Calcium-accumulating cells in the meristematic region of grapevine root apices.

Apical roots of grapevines were examined by cryo-SEM (scanning electron microscopy) and the intracellular distribution of Ca was demonstrated by X-ray microanalysis in different regions of the primary root. We show that large amounts of Ca are accumulated as raphide crystals in the vacuoles of specialised cortical cells (idioblast cells) of the root apex. These crystal idioblast cells appeared to form a discontinuous cone of cells in the outer region of the root meristem. The raphide crystals within these cells were less apparent in older regions of the root, 10-12 mm basipetal to the root tip. We suggest that the raphide crystals could initially act as another Ca sink involved in the regulation of Ca levels in root apices. In older regions of the root these cells are spaced at intervals around the periphery of the cortex and the subsequent disappearance of the raphides may be indicative of remobilisation, perhaps in the zone of elongation where cell wall synthesis occurs and Ca demand is high. Calcium-accumulating cells were also observed in the older regions of the root, forming endodermal protrusions extending into the cortex. These cells may play a part in regulating Ca delivery to the xylem stream by sequestration of Ca from the radial flow of water at the endodermis. The observed distribution of Ca in root apices was different from the other major cations (e.g. K) and anions (e.g. Cl) because high concentrations were localised to specific cells. We interpret the results in the context of a model of the dynamics of grapevine root growth and cell differentiation, and the temporal balance of solute supply from the protophloem and the external medium.
The social organization of sperm whales in the Gulf of California and comparisons with other populations

Intra-specific variation in social organization provides valuable insights into the selective forces driving social evolution. Sperm whales are distributed globally and live far from shore, thus obtaining large sample sizes on social organization in multiple areas is logistically challenging and few comparative studies exist. In order to address how ecological factors influence sociality, we investigated the social organization of sperm whales in the Gulf of California (GoC) using a long-term study (1998–2004) and compare our results to other published studies. Standard photo-identification and behavioural observation techniques were used. Group size was calculated from photographic mark–recaptures using a Petersen estimator. Social organization was investigated using SocProg 2.3. Mean typical group sizes in the GoC were similar to those in the Galápagos Islands, Chile and Seychelles (24.7, 24.8, 30.4 and 18 individuals respectively), but substantially larger than in the Sargasso Sea, Caribbean and northern Gulf of Mexico (12.0, 6.4 and 6.9 individuals respectively). Sperm whale social organization in the GoC best fitted a constant companion/casual acquaintance model, where permanent units sizes were 12.5 individuals and two units usually associated together to form a group. This structure is similar to the situation in the Galápagos Islands and Chile areas. However, groups were more stable in the GoC than in the South Pacific, as groups stayed together for periods of about 80 days versus about ten days in the Galápagos Islands and Chile. It is likely that differences in the social organization between the study areas in the Pacific and Atlantic Oceans were due to differences in predation pressure and/or food resources. We suggest that, site-specific ecological factors are likely to influence fundamental aspects of sperm whale social organization.
On the Advent of Fractional Calculus in Econophysics via Continuous-Time Random Walk

In this survey article, at first, the author describes how he was involved in the late 1990s on Econophysics, considered in those times an emerging science. Inside a group of colleagues the methods of the Fractional Calculus were developed to deal with the continuous-time random walks adopted to model the tick-by-tick dynamics of financial markets Then, the analytical results of this approach are presented pointing out the relevance of the Mittag-Leffler function. The consistence of the theoretical analysis is validated with fitting the survival probability for certain futures (BUND and BTP) traded in 1997 at LIFFE, London. Most of the theoretical and numerical results (including figures) reported in this paper were presented by the author at the first Nikkei symposium on Econophysics, held in Tokyo on November 2000 under the title “Empirical Science of Financial Fluctuations” on behalf of his colleagues and published by Springer. The author acknowledges Springer for the license permission of re-using this material.
From Roscovitine to CYC202 to Seliciclib – from bench to bedside: discovery and development

This monograph reviews the discovery and development of the cyclindependent kinase inhibitor roscovitine (R-roscovitine, CYC202, Seliciclib). The authors summarise the in vitro and in vivo data that have formed the basis for clinical investigation of Seliciclib as an anti-cancer drug. Kinase selectivity, cellular effects and the pharmacological properties of the drug are discussed in addition to the clinical results of Seliciclib being reviewed. Novel results on the effect of the drug in cardiac hypertrophy are summarized and potential applications of Seliciclib in other therapeutic areas, including, inflammation, virology, glomerulonephritis and polycystic kidney disease, are discussed. Finally the authors argue that optimisation of the therapeutic effect of kinase inhibitors such as Seliciclib can be enhanced using a systems biology approach involving mathematical modelling of the molecular pathways regulating cell growth and division.
New Aspects of the α-Helix to β-Sheet Transition in Stretched Hard α-Keratin Fibers

The putative transformation of α-helices into β-sheets has been studied for more than 50 years in the case of hard α-keratin. In a previous study of stretched keratin fibers, we specified the conditions for β-sheet appearance within horsehair: the formation of β-sheets requires at least 30% relative humidity. However, this phenomenon was observed in the whole tissue. Then there was no clear chemical identification of the β-sheets (keratin or matrix proteins) and the exact location of the β-sheets across the fiber could not be specified. In this study, using wide-angle x-ray scattering and high spatial resolution infrared microspectroscopy, we could determine and characterize the structural elements across hair sections stretched in water, which provides new information about the aforementioned transition. Our results show that the process can be split into three steps: 1), unraveling of the α-helical coiled-coil domains, which starts at roughly 5% macroscopic strain; 2), further transformation of the unraveled coiled-coils into β-sheet structures, which occurs above roughly 20% macroscopic strain; and 3), spatial expanding of the β-structured zones from the sample center to its periphery.
Tsukamurella gen. nov. Harboring Corynebacterium paurometabolum and Rhodococcus aurantiacus

Reverse transcriptase sequencing of long regions of 16S ribosomal ribonucleic acids of Corynebacterium paurometabolum and Rhodococcus aurantiacus was performed to determine the relationship of these organisms to other mycolic acid-containing actinomycetes. These two species were highly related to each other (more than 99% sequence homology in a large stretch of 1,184 nucleotides) but were distinct from the genera Corynebacterium, Mycobacterium, Nocardia, and Rhodococcus. On the basis of our findings and previous findings we propose that C. paurometabolum and R. aurantiacus be reduced to a single species and reclassified in a new genus, Tsukamurella. The type species is Tsukamurella paurometabolum comb. nov.
Effects of enzymes in diets with varying energy levels on growth and egg production performance of Japanese quail

The present study was conducted to evaluate the effect of feed-grade enzyme supplementation in diets with varying levels of energy on the performance of growing and laying Japanese quails. Day-old Japanese quails, 504 in number, were subjected to six dietary treatments with six replicates at each treatment. Each replicate had 14 chicks. The dietary treatments consisted of three energy levels ie 12.15 MJ (2900 kcal), 11.30 MJ (2700 kcal) and 10.48 MJ (2500 kcal) ME kg−1 diet and two enzyme levels (0 and 0.5 g kg−1 diet). A metabolism trial was conducted at the fourth week of age. At the end of week 5, 10 quails (five of each sex) per treatment were sacrificed for carcass characteristics and 20 female quails from each of the six dietary groups were housed in individual laying cages and fed respective layer diet to study the laying performance and egg quality up to 20 weeks of age. Body weight gains of quails fed 12.15 MJ or 11.30 MJ ME kg−1 diets were significantly higher (p < 0.01) than those fed diets with 10.46 MJ ME kg−1 diet. Feed intake was significantly lower (p < 0.01) in birds that received diet with 12.15 MJ ME kg−1 than in birds that diets containing either 11.30 or 10.46 MJ ME kg−1 diet. Feed conversion ratio (p < 0.01) was best at 12.15, followed by 11.30 and 10.46 MJ ME kg−1 diet. Enzyme supplementation did not improve the growth performance, feed intake or feed conversion efficiency of quails. Enzyme addition also did not influence nitrogen retention or energy or dry matter metabolizability. The carcass characteristics did not differ because of energy or enzyme supplementation. Feed intake increased significantly (p < 0.01) as the dietary energy level decreased. The egg production and quality characteristics remained almost similar in all the dietary treatments. It was concluded that the optimum dietary energy level for quail was 12.15 MJ (2900 kcal) ME kg−1 during the growing phase and 11.30 MJ (2700 kcal) ME kg−1 during the laying phase. Addition of feed enzymes to conventional diets containing varying levels of maize, soyabean meal, fish meal and deoiled rice bran was not beneficial to improve growth, carcass traits, egg production performance or nutrient utilization. Copyright © 2004 Society of Chemical Industry
A molecular electron density theory study of the participation of tetrazines in aza-Diels–Alder reactions

The reactions of eight tetrazines of increased electrophilic character with nucleophilic tetramethyl ethylene (TME) and with electrophilic tetracyanoethylene (TCE) have been studied using Molecular Electron Density Theory. These reactions are domino processes comprising an aza-Diels–Alder (ADA) reaction followed by an extrusion of molecular nitrogen, yielding a dihydropyridazine. Analysis of the conceptual DFT (CDFT) indices showed an increase of the electrophilicity and a decrease of the nucleophilicity of tetrazines with an increase of the electron-withdrawing character of the substituent. A very good correlation between the global electron density transfer at the transition structures and the activation enthalpies for the ADA reactions involving TME was found. However, tetrazines have no tendency to react with electrophilic ethylenes such as TCE. Bonding Evolution Theory (BET) analysis of the ADA reaction of dinitro tetrazine with TME showed that the activation energy is mainly associated with the continuous depopulation of the C–C and C–N double bonds.
Photosynthetic performance of cold‐sensitive mutants of maize at low temperature

The virescent character is a genetic variant in pigmentation characterized by a delay in greening. Seedlings of the virescent mutants v1, v2, v3, v4, v13, v16, v18, v19 and v26 of maize exhibit chlorosis when grown at low temperature. Chlorotic leaves contain plastids that appear to have been arrested at an early stage of development. The results indicated that V16, V2, V3 and V4 loci control early stages of chloroplast development while V1, V13 and V19 may play a role at the end of development. The mutations in the V18 and V26 loci may control an intermediate step. At the pigment level, the virescent mutants of maize differ widely from analogous mutations existing in other plants. The mutations were characterized by a reduced amount of chlorophyll a and b (up to 100 times in v16) and chlorophyll a/b ratio above normal (up to 13.7 in v16). Lutein content was reduced in all mutants (less than 3% in v16 compared to wild type) but v13, while pigments of the xanthophyll cycle were found at higher levels in v1 and v13 (more than 10 and 90%, respectively). The v2, v3, v4, v16 and v18 mutants that are most depleted in β-carotene (36 times less in average than wild type) are also deprived in D1 and D2 polypeptides. Moreover, the v2, v3, v4, v16 and v18 mutants characterized by a lower accumulation in lutein are most depleted of light-harvesting complex II. All mutants possess a functioning, fully reversible, non-photochemical quenching mechanism. This is most developed in the v13 and v19 mutants (Φ n = 0.48 and 0.44, respectively). These two mutants also have a relatively high primary photochemical yield for photosystem II and a functioning photosystem I (Φ p = 0.23 and 0.39, respectively). The most interesting mutant is v13 that shows severe chlorosis and possesses the most effective non-photochemical quenching mechanism(s), which is thought to provide protection against excess photon absorption by photosystem II.
Nitrogen relationships and residual effects of intercropping sorghum with legumes

SUMMARY Intercropped with legumes, sorghum removed more N from the growing medium than when grown alone. 16N data showed that out of the total N removed by sorghum in a sorghum + mung mixture 18·1% was derived from the fertilizer urea and 81·9% came from the soil pool; the latter included 21·9 % N derived from current fixation by the legumes. When grown alone sorghum plants derived 18·6 % N from urea and 81·4 % from the soil. The yield of wheat grown in sequence was 5·13 t/ha after a previous sole crop of mung and 3·47 t/ha after sorghum. The yield of wheat after sole crops of legume was greater than after their mixture with sorghum. The latter was, however, greater than its yield after sole sorghum. The economic optimum rate of N required after wheat, computed from an experiment with several rates of applied N on an adjacent plot, was 124 and 105 kg N/ha at expected yields of 5·2 and 4·5 t/ha of wheat respectively. By interpolation the relative yield advantage from sole legumes ranged between 28 and 68 kg N/ha in 1982–3 and was more than 90 kg N/ha in the next year. These advantages from legume + non-legume mixtures equalled 12–17 kg N/ha applied to wheat, in addition to 50 kg N/ha applied uniformly to the sequential crop of wheat.
Antibiotic Susceptibility of Lactobacilli Isolated from the Cervix of Healthy Women

During antibiotic treatments normal vaginal microflora can be replaced by resistant bacteria or fungi. The resulting infections are considered an unavoidable side effect. This study is aimed at identifying antibiotics with low activity against lactobacilli. Fifty isolates from 30 cervix specimens collected from 30 healthy women during colposcopy, typed by API 50CHL as lactobacilli, were tested for susceptibility to 41 antibiotics using the Bauer-Kirby test. The test was easy to perform and to interpret. Aztreonam, fusidic acid, cefixime, kanamycin and pefloxacin showed less activity against lactobacilli (72-86% of resistant isolates). All isolates were found to be susceptible to imipenem and piperacillin-tazobactam. Vancomycin showed higher antibacterial activity (22% of resistant isolates) than teicoplanin (54% resistance). Antibiotic treatments have to take into account the susceptibility of normal vaginal microflora to prevent colonization by resistant pathogenic microorganisms.
Contrast-enhanced magnetic resonance (MR) T1 mapping with low-dose gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) is promising in identifying clear cell renal cell carcinoma histopathological grade and differentiating fat-poor angiomyolipoma.

Background This study aimed to identify clear cell renal cell carcinoma (ccRCC) histopathological grade and differentiate it from fat-poor angiomyolipoma (AML). This was achieved through contrast-enhanced magnetic resonance (MR) T1 mapping with intravenous low-dose gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). Methods In total, 56 consecutive patients received MR scanning between January 2016 and December 2018 using the pre- and post- contrast-enhanced T1 mapping sequences with low-dose Gd-DTPA (0.036 mmol/kg). RCCs were pathologically proven in 40 patients after surgery and graded according to the International Society of Urological Pathology (ISUP) classification system. Ten AMLs were pathologically proven by surgery histopathology and six AMLs were diagnosed by magnetic resonance imaging (MRI). Patients were followed up for more than half a year. The mean T1 values of the renal lesion and ipsilateral normal renal parenchyma were measured before and after Gd-DTPA administration (T1p and T1e). The reduction of T1 value (T1d) and the ratio of its reduction (T1d %) were calculated and compared. Results In 40 ccRCCs, higher-grade [International Society of Urologic Pathology (ISUP) grade 3 and 4] and lower-grade (ISUP grade 1 and 2) ccRCCs were noted in 13 and 27 patients, respectively. The mean T1p was 1,514.8±139.4 ms and the mean T1d was 907.7±193.7 ms in the higher-grade ccRCCs, which were significantly higher than in the lower-grade ccRCCs (T1p =1,251.7±151.5 ms and T1d =648.5±218.2 ms, respectively; P<0.001). Fat-poor AMLs had higher T1p (1,677.3±104.8 ms) and T1e (865.6±251.5 ms) as compared to ccRCCs (P<0.001). Combined T1p + T1d showed the highest area under the curve (AUC) (0.912) in the differentiation of higher-grade ccRCCs from lower-grade ccRCCs (P=0.010). Combined T1p + T1e had the highest AUC (0.956) in the differentiation between ccRCCs and fat-poor AMLs (P=0.010). All T1 mapping metrics could discriminate between normal renal parenchyma and renal lesions (P<0.001). No significant difference was found in the T1p and T1e at different parts of the ipsilateral normal renal parenchyma. Interobserver agreement for quantitative longitudinal relaxation time in the T1 maps was excellent. Conclusions Contrast-enhanced T1 mapping with low-dose Gd-DTPA may provide a more reliable and accurate approach in identifying ccRCCs histopathological grade and differentiating ccRCCs from fat-poor AMLs.