Miracle-dz/UniFAR-FTUs huggingface dataset:
Computing services for disabled students in institutions of higher education

Individuals with disabilities have faced substantial barriers in pursuing higher education. Few institutions made serious efforts to be accessible until legislation demanded nondiscrimination on the basis of handicap. Federal legislation is generally interpreted to mean that schools must provide access to computers with appropriate adaptive technology to students with disabilities when such access is required to pursue academic studies. Accommodations are to be made in the most integrated setting appropriate. However, for many disable students, discrimination in access to computing resources persists. This study explores issues surrounding the provision of computing services to disabled students in institutions of higher education. The results of a survey of schools with enrollments of 1,000 or more students reveal that computing services for students with disabilities are underdeveloped at many schools, with some schools providing no services in this area. The office of disabled student services is the organizational unit most involved in the selection, funding, and management of the services that are provided. Two-year, public, and larger schools tend to provide a greater number of computing services for disabled students and a greater number of types of adaptive devices and to assign staff to specifically support disabled students than four-year, private, and smaller schools, respectively. Access to electronic services for students with disabilities is very limited at most schools. Those who provide some computing services for students with disabilities tend to integrate them into facilities used by other students and this integrated model is generally preferred by staff. Staff generally rate moderately high both the abilities of disabled students to make productive use of computers and the contribution computers make to the academic success of these students. They consider funding the greatest barrier to providing computing services to students with disabilities. The results of this study may help administrators make better decisions regarding the provision of computing services to students with disabilities and thereby better serve these students. The results suggest that institutions must make greater efforts to assure nondiscrimination on the basis of disability regarding access to computing services.
Problematic use of mobile phone and nomophobia among French college students

Introduction Identify problematic use of mobile phone (MP), nomophobia (« No mobile phone phobia ») and associated behaviors among French college students. Methods During the 2013–2014 university period, students from Upper-Normandy (France) filled in a self-administered anonymous questionnaire that has collected information on the ownership of smartphone and frequency of use of the MP (calling, texting and surfing the web). Frequency of awakenings at night …
A retrospective analysis of electrocardiographic abnormalities found in black South African patients with diabetes attending a regional hospital in KwaZulu-Natal

Objectives: Diabetes mellitus increases the risk of coronary heart disease and myocardial infarction (MI). Silent MI occurs with greater frequency in patients with diabetes with or without autonomic neuropathy and carries a similar prognosis to overt MI. Regular electrocardiographic (ECG) assessment is integral in the chronic management of patients with diabetes. Limited data exist on the spectrum of ECG abnormalities of black South African patients with diabetes. The primary aim of this study was a description of ECG abnormalities found and the secondary aim was the determination of factors associated with left ventricular hypertrophy (LVH) and MI. Setting and participants: The study was carried out at a regional hospital diabetes clinic in Pietermaritzburg, KwaZulu-Natal. The initial ECGs performed on patients from October 1, 2012 to September 30, 2014 were analysed. The first ECGs of 637 black South African patients with diabetes were studied, representing 80.1% of all eligible patients. Results: The major ECG abnormalities detected were those suggestive of LVH (36.0%), MI (21.7%), conduction defects (17.7%), T-wave inversion (14.1%) and ventricular ectopics (6.8%). Most infarctions were silent (89.8%), and affected the inferior territory significantly more than anterior, lateral and antero-lateral territories (52.9% vs. 33.3% vs. 9.4% vs. 1. 5%, respectively). A substantial percentage of patients with MI failed to achieve target HbA1c and triglyceride levels and waist-to-height-ratios. Diet, exercise and self-monitoring of glucose were all associated with positive effects on both MI and LVH. A greater percentage of patients with LVH had evidence of MI versus those without hypertrophy (28.4% vs. 19.4%). Conclusion: This study demonstrates a high prevalence of undiagnosed MI within this cohort of South African patients with diabetes. Patients with LVH were more prone to infarction. Poor glycaemic and triglyceride control and obesity were associated with infarction. Improving glycaemic and lipid control together with lifestyle modification may help prevent macrovascular cardiac complications.
The effect of Interleukin-10 and of Interleukin-12 on the anti-double-stranded DNA antibody production by the blood lymphocytes of patients with systemic lupus erythematosus.

The effect of interleukin-10 and of interleukin-12 on the anti-double stranded DNA antibody production by the blood lymphocytes of patients with systemic lupus erythematosus. Systemic lupus erythematosus (SLE) is a chronic autoimmune rheumatic disease, characterised by B-cell hyperactivity and the presence of various autoantibodies. Anti-double stranded DNA antibodies (anti-dsDNA antibodies) are thought to be important in SLE pathogenisis as their serum titre often correlates with disease activity and they have been shown to induce lupus-like organ damage in many experimental models. If anti-dsDNA antibodies in patients with SLE were pathogenic, then the immune signals responsible for their expansion could be responsible for inducing disease flare. The cytokines interleukin-10 (IL-10) and interleukin-12 (IL-12) regulate antibody production in other systems and the levels of both of these cytokines are related to disease activity in SLE. Serum levels of IL-10 correlate positively with disease activity and the in vitro production of IL-12 correlates negatively with disease activity, moreover this deficit in IL-12 production is due to IL-10 overproduction. This observation raises the possibility that the imbalance between these two cytokines might be involved in anti-dsDNA antibody production. Cultures of blood mononuclear cells from SLE patients with different disease activities were treated with IL-10 or IL-12 and the resulting supernatants tested for their antibody production by ELISA; both cross-sectional and longitudinal studies were carried out. The results showed that the effect of IL-10 on antibody production varied with disease activity. Further experiments using depleted cell populations revealed that T-cells, but not monocytes, played a role in determining the effects of IL-10. Parallel experiments utilising flow cytometry revealed that IL-10 may exert some of its T-cell dependent effects on antibody production through the induction of apoptosis. IL-12 both increased and decreased anti-dsDNA antibody production and a number of different factors, including disease activity and inter-patient variation might be responsible for this. These findings are consistent with the role of IL-10 in the regulatory suppression of immune responses. The effect of IL-12 requires further examination.
Perinatal complications in intrahepatic cholestasis of pregnancy

Background and Objective: Intrahepatic cholestasis of pregnancy (ICP) is seen usually in 3rd trimester of pregnancy. Overall incidence is 1.2-1.5% of Indian pregnant women. The biochemical abnormalities often include raised liver enzymes, conjugated bilirubin and bile acids. ICP can complicate perinatal outcomes to a significant extent. The present study was conducted to find out the types and incidence of perinatal outcomes in pregnancy complicated with ICP diagnosed by abnormal LFTS (liver function tests), to help the clinician in initiating timely treatment. Materials and methods: In the present study, 51 pregnant women diagnosed with ICP and 49 number of age and gravida matched normal pregnant women were included as cases and controls respectively. LFT and Total bile acids were estimated by standard biochemical methods. Both cases and controls were followed to evaluate perinatal outcomes after 7 days of post- partum. Results: Total bilirubin (0.6 ± 0.08 Vs 0.4 ± 0.03)milligrams/decilitre*; Aspartate transaminases (48 ± 18.6 Vs 27 ± 9.5) International Units/ Litre**; Alanine transaminase (42 ± 14.2 Vs 28 ± 6.1) International Units/ Litre**; Alkaline phosphatase (251 ± 63 Vs 159 ± 58) International Units/ Litre**;Gamma glutamyl transferase (41 ± 5.2 Vs 35 ± 3.6) International Units/ Litre**; Total bile acids (12.7 ± 10.2 Vs 33.4 ± 15.6)µ mol/ Litre ; Albumin (3.3 ± 0.5 Vs 3.2 ± 0.4)grams/decilitre; Total Proteins(6.3 ± 1.2 Vs 6.1 ± 1.5)grams/decilitre were obtained in cases Vs controls. Significantly higher incidence of total complications in cases compared to controls(54.90% Vs 12.24%)*** were found which include respiratory distress(23.52 Vs 4.08)%***, meconium aspiration (9.80 Vs 2.04)%**, pre-term delivery (9.80 Vs 4.08)%*, hyperbilirubinemia (1.96 Vs 0.0)%, fetal bradycardia (7.84 Vs 2.04)%** and fetal loss(1.96 Vs 0.0)%. (*p value
Effect of essential oils on the course of experimental atherosclerosis

: The effect of volatile oils of lavender, monarda, and basil on the course of experimental atherosclerosis was studied in rabbit experiments. Inhalation of the volatile fractions of essential++ oils of lavender and monarda in a concentration of 0.1-0.2 mg/m3 of air has no effect on the content of cholesterol in the blood, but reduces its content in the aorta and reduces affection of the aorta by the atherosclerotic plaques, i.e. these oils produce an angioprotective effect.
Clinical Implications of Genetic Testing for Hereditary Breast and Ovarian Cancer Syndrome in the Era of Genomic Medicine: Clinician’s Perspectives

Clinical Implications of Genetic Testing for Hereditary Breast and Ovarian Cancer Syndrome in the Era of Genomic Medicine: Clinician’s Perspectives Hyung Seok Park*, Ji Soo Park*, Eun Ji Nam, Seung-Tae Lee, Jung Woo Han, Tae Il Kim Department of Surgery, Yonsei University College of Medicine; Hereditary Cancer Clinic, Cancer Prevention Center, Yonsei Cancer Center, Yonsei University College of Medicine; Women’s Cancer Clinic, Division of Gynecologic Oncology, Institute of Women’s Life Medical Science, Department of Obstetrics and Gynecology, Yonsei University College of Medicine; Department of Laboratory Medicine, Yonsei University College of Medicine; Department of Pediatrics, Yonsei University College of Medicine and Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
Headache diagnosis, management and morbidity in the Singapore primary care setting: findings from a general practice survey.

Introduction: We sought to determine the epidemiological features and the headache burden of headache patients in the Singapore primary care setting. Particular attention was given to the adequacy of migraine diagnosis and management as well as the utilisation of prophylactic medication by primary care doctors. Methods: Consenting patients who consulted participating general practice clinics with the chief complaint of headache, were administered a questionnaire incorporating demographical data, headache characteristics and burden as well as treatment patterns. For each patient, the attending doctor independently completed a second questionnaire covering diagnosis and treatment of the patient. Results: A disproportionate number of non-Chinese and females presented for headache management in the primary care setting as compared to the Singapore population at large. Migraineurs had more headache-related disability (67.3 percent) than non-migraineurs (45.7 percent). In our study setting, the IHS diagnostic criteria (38.2 percent of respondents), ID migraine (61.1 percent) and physician's diagnosis (62.0 percent) correlated poorly with each other when employed for case definition of migraine. In the study population, 22.6 percent used acute pain medication excessively (more than four days a week), 39.3 percent were dissatisfied with their current treatment and 58.3 percent had frequent headaches (more than four attacks a month). Only a minority of those in whom prophylaxis was indicated were treated appropriately. Conclusion: Diagnosis of migraine is inconsistent in the primary care setting despite the condition being responsible for considerable disability. Prophylactic treatment is underutilised as a management strategy, and the risk of medication-overuse headaches is underestimated. Our results emphasise the continuing need for education of primary care physicians and the public about strategies for effective headache diagnosis and treatment.
Vergleich der Stationsatmosphäre zwischen drei Spezialstationen für alkoholkranke, schizophrene und depressive Patienten und einer diagnostisch gemischten Satellitenstation

OBJECTIVE: Does the ward atmosphere differ between three specialized wards for patients with alcoholism, schizophrenia, and depression and a diagnostic heterogeneous satellite ward? METHODS: The ward atmosphere was assessed by patients and staff with the German version of the ward atmosphere scale (WAS). RESULTS: The data of 49 co-workers and 41 patients were evaluated. The satellite ward was rated significantly better than the specialized wards by both staff and patients (p < 0.01). CONCLUSIONS: If it is not possible to prove empirically, in future, that specialized wards have treatment advantages, our study suggests for atmospheric reasons that diagnostic heterogeneous wards should be recommended as standard care.
Assessment of mental health status of trainee anesthesiologists in a southern India tertiary care hospital

Background: Mental health among anaesthesiologists has been studied in India in a limited manner. In this study, we aim to assess the same in a group of trainee anesthesiologists. Methods: A cross sectional study was undertaken among all the anesthesiology registrars doing their post graduation at the Christian Medical College and Hospital, a tertiary care hospital in southern India. The mental health was assessed using General Health Questionnaire - 28 (GHQ 28). Results: 43% of the study group was found to have higher levels of emotional distress. Significant correlation was found for female registrars and those between 20 and 30 years of age. Conclusion: While nearly half of trainee anaesthesiologists were found to have higher levels of emotional distress, the association was most marked among women and, individuals under 30 years of age.
Binge drinking in tuberous sclerosis successfully treated with valproate: A case report

Tuberous sclerosis complex (TSC) is a genetic condition (Curatolo et al., 2008) characterized by various physical and neurocognitive features. TSC can cause tumors in the skin, kidneys, brain, heart, eyes, lungs, teeth as well as other organ systems. The disease affects some people severely, while others are so mildly affected that it often goes undiagnosed. Studies report a wide range of skin lesions in patients with TSC (Jóźwiak et al., 1998) which include hypopigmented macules, facial angiofibromas, forehead or scalp plaques, shagreen patches and renal lesions like renal cysts, angiomyolipomas amongst others. Seizures are the most common presenting symptoms in tuberous sclerosis and typically develop in childhood. Studies have reported disruptive behaviours including over activity, restlessness, impulsivity, anger outbursts, temper tantrums, and self-injurious behaviours in 40–50% of the patients with TSC. Other symptoms include depressed mood, anxiety, extreme shyness and sleep problems (Kopp et al., 2008) in children and adolescents with TSC. These symptoms may be accompanied by either normal or subnormal intelligence (De Vries et al., 2007; Harrison et al., 1999). Binge drinking is defined as consumption of 5 drinks (in case of men) or 4 drinks (in case of women) within two hours, such that the blood alcohol concentration (BAC) is raised to 0.08 gram percent or above (Scaife & Duka, 2009). Studies have reported impairments in frontal lobe functioning including working memory in persons engaging in binge-drinking (Chung et al., 2011; Scaife & Duka, 2009; Mackillop et al., 2007). TSC with binge drinking presents a problematic clinical situation and treatment options are not very well studied. Below we describe a case of tuberous sclerosis associated with binge drinking successfully treated with valproate. Case report
Lesiones y neoplasias del tracto genital femenino relacionadas con la infección por el virus del papiloma humano. Impacto previsible de la vacunación profiláctica

Resumen “El descubrimiento de que el cáncer de cérvix es la rara consecuencia de una infección frecuente ha sido tan impactante para la salud pública como la demostración de la asociación existente entre el tabaco y el cáncer de pulmón. ” Si bien la infección por virus del papiloma humano (VPH) desaparece espontáneamente la mayoría de las veces, desde el año 1999 sabemos que es el factor etiológico causante del cáncer de cérvix; posteriormente se ha demostrado su asociación no sólo con las lesiones precursoras de este tumor sino también con otras neoplasias y sus precursores de vulva, vagina, ano, pene y orofaringe. Asimismo está demostrado que determinados tipos de VPH son los causantes de procesos no neoplásicos como los condilomas genitales y la papilomatosis respiratoria recurrente. En la presente revisión se analizan todos estos procesos, el papel etiopatogénico de los diferentes tipos de VPH, su incidencia, impacto sanitario y mortalidad, así como los procedimientos diagnósticos y terapéuticos que conllevan. Mientras las lesiones neoplásicas se asocian fundamentalmente a la presencia de los llamados VPH de alto riesgo basándose en su potencial carcinogenético (tipos más frecuentes: 16 y 18), las lesiones no neoplásicas lo hacen a los VPH de bajo riesgo (tipos 6 y 11). La reciente aprobación de una vacuna tetravalente eficaz frente a estos cuatro tipos de virus (6, 11, 16 y 18) hace previsible un importante impacto a medio plazo sobre la incidencia y, por tanto, sobre la mortalidad asociada a ellos. Palabras clave: Cáncer cervical, Cáncer vulvar, Neoplasia cervical intraepitelial, Neoplasia vulvar intraepitelial, Cáncer anal, Neoplasia anal intraepitelial, Verrugas genitales, Vacuna contra el virus del papiloma humano.
An Interesting Presentation Of Eagle Syndrome

Eagle syndrome is a relatively rare disorder whereby a calcified stylohyoid ligament or elongated styloid process give rise to a multitude of otolaryngological symptoms. We describe a case whereby a gentleman was referred with a bona fida reason for having a pharyngeal foreign body, but was found to have an elongated styloid process and symptoms related to this.
Stigma and Mental Illness: Pilot Study of Laypersons and Health Care Providers with the EMIC in Rural West Bengal, India

Objective: Recognizing the importance of stigma as an important factor in mental illness, intensifying the suffering and interfering with efforts to seek useful help, this study examined indicators of stigma for various mental health problems among laypersons and health care providers (HCP) of various kinds in a rural community of rural West Bengal, India. Method: An instrument for study of cultural representations of illness, the EMIC, was adopted and translated into Bengali and administered to a random sample of 21 Iaypersons and 17 health care providers in a rural area of West Bengal. These interviews examined indicators of stigma based on Goffman’s concept of spoiled identity with reference to the following mental health problems: depression, somatoform disorders, deliberate self-harm, psychosis, hysteria and possession. Case vignettes depicting typical presentations of these conditions were the focus of these interviews. Results: The responses on the ‘stigma’ section of the EMIC from both the groups were analyzed and compared. A stigma scale based on indicators we examined was constructed and used to compare stigma between groups and for different conditions. It was found that indicators of mental illness-related stigma were more prominent among health care providers compared with laypersons. Self-perceived stigma was also higher among female laypersons than males. Among the various mental health problems we examined, stigma was greatest for deliberate self-harm. Conclusion: Stigma is a great impediment for early detection and treatment of mental diseases. The high level of stigma in the illness representations of health care providers indicates the need for mental health awareness programmes targeting them as well as laypersons. Although findings from this pilot study are tentative, it indicates an approach to studying and comparing stigma that will be useful in designing and assessing the effectiveness of public mental health policy and programmes.
Efecto del consumo de una fórmula con carbohidratos de liberación prolongada sobre la respuesta glicémica e insulina post-prandial en individuos sanos

There are specific formulas of enteral nutrition to improve glycemic control in diabetic patients containing different types of carbohydrates which glycemic response should be investigated. The consumption effect of a formula with carbohydrates with extended release was determined on the glycemic response and postprandial insulin in 21 healthy individuals (11 men and 10 women) from 17 to 25 years old, who consumed in two different time the polymeric enteral formula for diabetics and the reference food (white bread) in a quantity of 50 g of available carbohydrates. The glycemia was measured at 0, 15, 30, 45, 60, 75, 90, 105 and 120 min and the insulin concentrations in fasting and within 120 min. The area in the glycemic curve was measured being the lowest the formula 11718.20. ± 1112.38 than in white bread 13269.18 ± 1351.05 (P<0.001). The glycemic index (GI) resulted to be intermediate (63.33±5.22) and lower when compared to the GT ranks published for the reference food (80-96). A lower concentration of glycemia occurred after the consumption of the formula, without increments in the insulin requirements; thus, assuming an adequate use in diabetic and a more extended feeling of fullness. This effect and the glycated hemoglobin should be studied after the extended consumption in people with diabetes.