Miracle-dz/UniFAR-FTUs huggingface dataset:
Examining the associations between sleep behaviours, emotional regulation and distress

Difficulties with maintaining optimal sleep behaviours are widespread. Evidence suggests significant relationships between sleep disturbances and health outcomes, with consequences including increased risk, severity, and difficulties with management of health conditions. Disrupted sleep behaviours are associated with inefficient self-regulation and emotional regulation suggesting sleep behaviours as a modifiable risk factor for inclusion in psychological interventions for health management.Systematic literature review:Social jetlag (SJL), a misalignment between mid-point of sleep on work and free days, has been suggested as a factor in mental health. Biological and social changes characteristic of young people may increase propensity for SJL and distress. The narrative review included seven quantitative papers to assess the relationship between SJL and mental health in young people. Although evidence was equivocal, associations between depression and SJL in female participants particularly in high latitude regions were indicated. An agreed outcome set for mental health and sleep research should be developed to support further research into these relationships.Research project:Diabetes-related distress (DRD) is associated with poor emotional regulation and poor diabetes outcomes, whilst optimal sleep behaviours and self-compassion have been linked with improved emotional regulation and health outcomes. This cross-sectional study assessed relationships between sleep behaviours, self-compassion, and DRD in a sample of people with type 2 diabetes mellitus (n=136). Statistical analysis identified significant associations between sleep behaviours, DRD, and self-compassion. Daytime sleepiness, SJL, age, total self-compassion, and negative subscales of self-compassion were unique predictors of DRD, with daytime sleepiness partially mediating the relationship between self-compassion and DRD. Psychological work to reduce DRD should focus on reducing negative traits of self-compassion and include consideration of sleep behaviours. Further research is needed to establish causality and long-term impact, as well as to develop clinical resources to support the effective management of the psychological impact of DRD.
A Rare Neurological Involvement in Sjögrens Syndrome: Abducens Nerve Palsy

DOI: 10.4328/JCAM.4392 Received: 11.02. 2016 Accepted: 06.03. 2016 Printed: 01.04. 2016 J Clin Anal Med 2016;7(suppl 2): 145-7 Corresponding Author: Yunus Ugan, Ayazmana Mah. , 4419. Cad. Metro City Vadi Evleri D Blok Daire: 16, 32000, Isparta, Turkey. T. : +9
Gendered Fitness Interests: A Method Partitioning the Effects of Family Composition on Socio-Political Attitudes and Behaviors

Whereas most people are biologically either male or female, their genetic interests are almost never aligned with just their own sex. Drawing on the evolutionary theory of inclusive fitness gained through relatives, we suggest it is possible to partition the effects of kin on fitness into those that derive from female versus male relatives. We argue that the balance of these female- and male-derived effects, which we call ‘Gendered Fitness Interests’ (GFI), might influence human behavior, especially the adoption of socio-political attitudes regarding issues with a gendered dimension. Our proposal builds on previous conjectures within evolution, as well as observations from both within and beyond the evolutionary sciences that parents’ socio-political views covary with the sex of their children, and the numbers of relatives of each sex. Further, it is consistent with the relatively small average differences between women’s and men’s socio-political positions. Using simulated data, we outline a method for partitioning GFI, and derive the testable predictions that the GFI component of women’s and men’s socio-political attitudes will converge with age, and with larger family sizes. Our proposal does not replace or falsify other theories of sex differences and similarities, but it does formalize a previously underappreciated component of variance in traits and attitudes with a gendered dimension. In this respect, it may be generally useful in resolving the complex origins of gendered behavior, and the primacy of an individual’s gender identification (including but not limited to biological sex) as a fixed and distinctive part of their socio-political identity.
Caminhamento Paralelo Barnes-Hut com Vetorização AVX2

O algoritmo Barnes-Hut é um método aproximado amplamente usado na simulação gravitacional de N -Corpos. A natureza irregular desse código apresenta desafios para sua computação em sistemas paralelos. Obstáculos adicionais ocorrem nesse padrão de computação quando se deseja a utilização eficaz da capacidade computacional de arquiteturas multicore com instruçoes SIMD. O enfoque deste trabalho é implementar e analisar a eficiência do caminhamento paralelo Barnes-Hut com octrees implı́citas e uso de instruções vetoriais AVX2. Os experimentos demonstram a efetividade do método, que apresenta altas taxas de GFLOP/s e economia de energia nas simulações.
Life History and Population Dynamics of Green Crabs (Carcinus maenas)

Carcinus maenas (the “shore crab” or “European green crab”) is a very proficient invader (considered to be one of the world’s 100 worst invaders by the IUCN) due to its phenotypic plasticity, wide temperature and salinity tolerance, and an extensive omnivorous diet. Native to Atlantic Europe, it has established two well-studied nonindigenous populations in the northwestern Atlantic and northeastern Pacific and less-studied populations in Australia, Argentina and South Africa. Green crabs are eurythermal and euryhaline as adults, but they are limited to temperate coastlines due to more restrictive temperature requirements for breeding and larval development. They cannot tolerate wave-swept open shores so are found in wave-protected sheltered bays, estuaries and harbors. Carcinus maenas has been the subject of numerous papers, with over 1000 published in the past decade. This review provides an up-to-date account of the current published information on the life history and population dynamics of this very important species, including genetic differentiation, habitat preferences, physical parameter tolerances, reproduction and larval development, sizes of crabs, densities of populations, sex ratios, ecosystem dynamics and ecological impacts in the various established global populations of green crabs.
The Center for Promoting Health and Health Equality’s Racial and Ethnic Approaches to Community Health Program

African-Americans in Douglas County, Nebraska, experience above-average incidence of death and disability from chronic diseases, particularly cardiovascular disease. Current screening and education services are independent and poorly available to minority citizens. Despite communities’ progress in addressing health disparities, barriers prevent effective and culturally-competent care. Addressing these inequalities requires new and innovative models like Creighton University’s Center for Promoting Health and Health Equity, Racial and Ethnic Approaches to Community Health (CPHHE-REACH) program. This collaborative partnership with community stakeholders in Douglas County, Nebraska addresses chronic disease disparities in Omaha African-Americans by increasing community opportunities for access to physical activities. The REACH strategy involves promoting and supporting changes in policy, systems and environment (PSE). The Omaha African-American community for REACH comprises some 50,000 people. REACH program settings include Omaha faith-based organizations (churches of diverse denominations), public housing towers, a federally qualified health center, and public middle schools’ after-school program. The Douglas County Health Department and Creighton University School of Medicine personnel are key partners that provide technical assistance through the Physical Activity Leadership Train-the- Trainer mechanism for Community Health Ambassadors (CHAs) and direct support for (PSE) improvements. Thirtytwo (32) program-certified CHAs support enhancing access to physical activity in the affiliated public housing towers, diverse faith-based organizations, the health center, and the after-school programs.
Primary operation in synchroneous metastasized invasive breast cancer patients: First oncologic outcomes of the prospective randomized phase III ABCSG 28 POSYTIVE trial.

557Background: The ABCSG 28 Posytive trial compared primary surgery versus primary systemic therapy without surgery in stage IV breast cancer patients. The primary aim was to investigate whether immediate resection of the primary tumor followed by standard systemic therapy improves median survival compared with no surgical resection (NCT01015625). The trial had to be stopped early due insufficient recruitment. Methods: Untreated stage IV breast cancer patients with the primary in situ were randomly assigned to either surgery of the primary versus no surgery followed by systemic therapy between 2011 and 2015 in 15 breast health centers in Austria. Systemic therapy included endocrine therapy or chemotherapy. Patients were routinely followed every 3-6 months. Primary endpoint was median survival. Results: 90 patients (45 with surgery, 45 with primary systemic therapy without surgery) were randomized. Stratification criteria were age, endocrine responsiveness, her2 expression, planned first line therapy and b.
Carboxylated-cellulose nanofibers from oil palm empty fruit bunches enhanced extractive fermentation in microbial biobutanol production

Nanocellulose produced by 2, 2, 6, 6-tetramethylpiperidine-1-oxyl (TEMPO)-catalyzed oxidation, described as TEMPO-oxidized cellulose nanofibers (TOCNs), has a high density of negative charges on its surface. Its use in microbial fermentation systems is expected to be beneficial. In particular, microbial stability is required in acetone–butanol–ethanol (ABE) fermentation. Here, TOCNs derived from oil palm empty fruit bunches pulp were added to extractive ABE fermentation media, followed by microbial fermentation. The results showed that the presence of TOCNs induced higher total butanol production in broth by improving the growth environment of Clostridium saccharoperbutylacetonicum N1-4, which was used as the butanol-producing strain. Electrostatic repulsion between anionic surface carboxylate groups of TOCNs and negatively-charged bacteria made a positive contribution to the microenvironment for bacterial growth. The addition of TOCNs to fermentation media had significant positive effects on the total butanol yield density cell weight (DCW).
Adaptive mesh size (AMS) algorithm for energy efficiency maximisation in underlay D2D communication

The need to maximise energy efficiency (EE) for device-to-device (D2D) communication has become an urgent necessity for the fifth-generation wireless networks. In this study, the power allocation problem is considered for the cellular system underlaid with D2D users (DUs) to maximise the EE for the whole network. Firstly, the random distribution of DUs and cellular users (CUs) are described by utilising the homogeneous Poisson point process based on stochastic geometry. Secondly, successful transmission probabilities are deduced. Finally, the optimisation problem for maximising EE is formulated to determine the optimal power values for both D2D and CUs. An adaptive mesh size algorithm is suggested to solve the non-convexity of the EE optimisation problem. Simulation results prove that the suggested technique has the ability to accomplish the near-optimal EE. Furthermore, it has superior performance when compared with the related algorithms.
Differences of Visual, Auditorial, Kinesthetic Students in Understanding Mathematics Problems

Characteristics of students who are diverse, such as different learning styles will also lead to the possibility of differences in students' ability to understand the learning material and every problem given, especially at the stage of understanding the problem given, because this stage is the most important step to determine the next problem-solving step. Therefore this study aims to reveal and illustrate how different characteristics of visual, audio and kinesthetic students in understanding problems. Data retrieval was done in class VIII of Arjasa 1 Junior High School with test methods, interviews, and questionnaires. Data were analyzed through stages of data reduction, analysis, and decision making. Furthermore, based on the data analysis that has been done, it can be concluded that there are differences in the characteristics of understanding problems for visual, auditory and kinesthetic students in terms of completeness and regularity of information writing, quantity of repetition of reading questions, marking important information and activity/movement habits done during the process of understanding the problem.
Experimental evidence that the invasive snail Potamopyrgus antipodarum (Gray, 1843) survives passage through the digestive tract of common riverine fish

Potamopyrgus antipodarum is one of the most widespread invasive species worldwide and its expansion is ongoing. Although the snail has already been documented as surviving the digestive tract of various fish, there is insufficient data on potential riverine fish predators of P. antipodarum and of the ability of the snail to survive digestion by these fish. Lotic ecosystems are unfavourable for the upstream spread of this species by active movement and thus it is suspected that benthivorous riverine fish facilitate such upstream dispersion. In general, the results of this study indicated that P. antipodarum is not a preferable food object for the studied riverine fish. The study did indicate, however, that the invasive snail is capable of surviving the digestive tract of all the studied fish. As accidental consumption of abundant P. antipodarum with other food objects has already been documented, this study suggests that riverine fish can act as potential secondary dispersion vectors, facilitating the upstream dispersion of the snail.
Dürtüsellik ile Sosyal Medya Aşerme Arasındaki İlişkide FOMO’nun Aracılık Etkisi

In this study, the mediating effect was tested. The mediator effect of FOMO was tested in the relationship between impulsivity and social media craving. The participants of the study consisted of 251 individuals, 106 of whom were females and 145 of whom were males. Barratt Impulsivity Scale, Social Media Craving Scale and fear of missing out Scala were used in the study. Mediation analysis were performed using Hayes’ (2017) process application. The power of impulsivity to interpret FOMO has been studied and it has been determined that impulsivity predicts FOMO in a meaningful way (F=12.99, R2=.05, p<.0001). Impulsivity explains 5% of the total variance in FOMO. 2nd ed. when the model was passed, the power of impulsivity to process Social Media craving was examined and the result was determined as significant. (F=7.41, R2=.03, p<.0001). 3. In the model, the mediated effect of FOMO in the relationship between impulsivity and social media craving was examined and it was determined that FOMO showed a full mediated effect (F=22.19, R2=.15, p<.0001). The power of impulsivity to predict social media craving was 3% in the total variant, while the variance was up to 15% with the inclusion of FOMO in the analysis. The results of Sobel and Bootstrapping tests were determined to be statistically significant in order to determine whether the indirect effect was significant (Sobel Z = -4.62, p <.0001).
Epilepsiechirurgie bei Kindern und Jugendlichen

Zusammenfassung Die Epilepsiechirurgie hat sich in den letzten Jahren als eine besonders wirksame Behandlungsoption bei Kindern und Jugendlichen mit pharmakoresistenten strukturellen Epilepsien etabliert. Dank der fortschreitenden Entwicklungen in der Neurochirurgie, Anästhesie und Intensivmedizin sind epilepsiechirurgische Eingriffe auch bei Säuglingen möglich und können hervorragende Ergebnisse liefern, vergleichbar mit den Ergebnissen bei Kindern und Jugendlichen. Spätestens bei nachgewiesener Pharmakoresistenz sollte bei Kindern mit strukturellen Epilepsien die Möglichkeit eines epilepsiechirurgischen Eingriffes erwogen und die entsprechende prächirurgische Diagnostik in einem Epilepsiezentrum mit pädiatrischer Expertise eingeleitet werden. Fokale kortikale Dysplasien und glioneuronale Tumore sind die häufigsten Ätiologien bei pädiatrischen Patienten, die epilepsiechirurgisch versorgt werden; in beiden Fällen hängt die postoperative Anfallsfreiheit von der Vollständigkeit der Resektion ab. Im Kindesalter dominieren die multilobären und hemisphärischen Eingriffe, im Gegensatz zu den Erwachsenenkohorten mit vorwiegend resektiven Eingriffen im Bereich des Temporallappens und nur wenigen extratemporalen und hemisphärischen Eingriffen. Die Ausdehnung der Eingriffe nimmt mit dem Alter der epilepsiechirurgischen Kandidaten ab. Kleinere Kinder benötigen oft größere Resektionen, können jedoch mögliche neurologische Defizite aufgrund der funktionellen Plastizität in der Regel gut kompensieren. Die postoperative Anfallsfreiheit hängt vom Epilepsiesyndrom, der zugrunde liegenden Ätiologie und der Abgrenzbarkeit des epileptogenen Areals ab. Zwei Drittel der Kinder bleiben im Langzeitverlauf nach einem epilepsiechirurgischen Eingriff anfallsfrei. Mit der Anfallskontrolle sind oftmals wesentliche Verbesserungen der Entwicklungsverläufe zu beobachten. Neben der Weiterentwicklung nicht-invasiver Methoden in der prächirurgischen Epilepsiediagnostik ist höchste Priorität, das Intervall zwischen Feststellung der Pharmakoresistenz, prächirurgischer Abklärung und epilepsiechirurgischer Behandlung bei geeigneten Kandidaten zu verkürzen. Multizentrische Studien mit längeren Beobachtungsintervallen sind dringend erforderlich, um die Prädiktoren der Anfallsfreiheit und der positiven psychomotorischen Entwicklung der Kinder zu identifizieren und eine verbesserte Kandidatenauswahl und Beratung der Patienten und deren Familien zu ermöglichen.
The Anatomical Dry Eye —A Different Form of Ocular Surface Disease Deserves Focus

Introduction: Dry eye disease is currently considered mainly tear film related ocular surface condition. This concept does, however, not respect ocular surface topography. The micro-anatomy of the corneal changes may lead to enhanced demands on the tear film and lead to significant complaints. However, they often remain undetected and hence untreated. It is suggested that the pathophysiology for an entire subgroup of dry eye disease patients is primarily of surface morphological nature. Methods: The tear film break up was observed and used to identify anatomical alterations in eyes of patients with dry eye complaints. The localization and pattern of TFBUT using fluorescein was compared between eye with normal surfaces and surface alterations. Results: Premature tear film rupture was localized at constantly same areas and did match changes on the ocular epitheliopathy in patients with diseases such as microcystic epithliopathy, MFD, and after excimer laser treatment. Disusssion: Whereas in normal surfaces TFBUT does occur within the floating tear film, the anatomical dry eye identifies itself with constant location of tear film break up and a constant spreading pattern. In contrast to the classic, tear film caused dry eye, the anatomical dry eye is accessible to treatment. This should catch our attention and intent to identify it. It is the ease of possible treatment that should make these ocular surface alterations prime target of dry eye disease diagnostic. It is hence suggested to introduce the anatomical dry eye as a subgroup in the large group of dry eye and ocular surface disease.
Medication use and Healthcare Outcomes in Developmentally Disabled Medicaid Adults with Type 2 Dibetes: a Quantitative Race Based Analysis.

Objectives: The prevalence of diabetes mellitus is high among patients with developmental disabilities (Cerebral Palsy, Autism, Down’s syndrome and cognitive disabilities). Developmentally disabled individuals experience delays in detection of chronic comorbidities, poor disease management and low quality of care. This research examines the racial health disparities in medication adherence and medication persistence in developmentally disabled adults with type 2 diabetes enrolled in Medicaid. Methods: This was a retrospective cohort study based on the Health belief model and Aday Anderson’s model of healthcare utilization. The dataset used for this research was the MarketScan® Multi-State Medicaid Database. Adults aged 18-64 years with a prior diagnosis of a developmental disability (cerebral palsy/autism/down’s/cognitive disabilities) and a new diagnosis of type 2 diabetes enrolled in Medicaid from January 1, 2004 and December 31, 2006, were included. Adults were included if they had a continuous enrollment for at least 12 months and were excluded if they were dual eligible. Anti-diabetic medication adherence and diabetic medication persistence were measured using multivariate logistic regression and the Coxproportional hazard regression respectively.
Delicate Balances in Cancer Chemotherapy: Modeling Immune Recruitment and Emergence of Systemic Drug Resistance

Metronomic chemotherapy can drastically enhance immunogenic tumor cell death. However, the responsible mechanisms are still incompletely understood. Here, we develop a mathematical model to elucidate the underlying complex interactions between tumor growth, immune system activation, and therapy-mediated immunogenic cell death. Our model is conceptually simple, yet it provides a surprisingly excellent fit to empirical data obtained from a GL261 mouse glioma model treated with cyclophosphamide on a metronomic schedule. The model includes terms representing immune recruitment as well as the emergence of drug resistance during prolonged metronomic treatments. Strikingly, a fixed set of parameters, not adjusted for individuals nor for drug schedule, excellently recapitulates experimental data across various drug regimens, including treatments administered at intervals ranging from 6 to 12 days. Additionally, the model predicts peak immune activation times, rediscovering experimental data that had not been used in parameter fitting or in model construction. The validated model was then used to make predictions about expected tumor-immune dynamics for novel drug administration schedules. Notably, the validated model suggests that immunostimulatory and immunosuppressive intermediates are responsible for the observed phenomena of resistance and immune cell recruitment, and thus for variation of responses with respect to different schedules of drug administration.
Rescuing path guidance method in a ship using genetic algorithm

화재 등의 재난 상황 시 대피 경로를 안내하기 위해 대부분의 건물, 선박 등의 구조물에서는 중앙통제센터나 안전요원의 안내나 대피 경로 유도등을 통해 대피 경로를 안내하고 있다. 하지만 규모가 커지고 갈수록 내부 구조가 복잡해짐에 따라 재난 상황에 대한 실시간 정보가 부족하여 상황에 대한 효과적인 대응이 어려우므로, 비상 상황 시 안전을 보장할 수 있는 지능적 안내 시스템의 필요성이 증가하고 있다. 따라서 분산적으로 배치된 센서들로부터 수집된 상황 데이터 정보에 기반하여 중앙서버에서 지능적으로 경로를 탐색하고 재난상황에서의 탈출을 유도하는 알고리즘이 제안되었다. 그러나 대피자의 효과적인 대피와 함께 중요한 부분이 구조자의 효율적인 구조활동이다. 현재까지 대피자의 대피 경로 유도에 대한 연구는 다양하게 이루어져왔으나, 구조자의 효율적 진입 경로 탐색에 대한 연구는 기본적인 방안의 설계에 그치고 있다. 따라서 본 논문에서는 센서 네트워크 환경에서 유전 알고리즘을 적용한 구조자 진입 경로 탐색 방안과 구조자원 투입량의 최적화 방안에 대해 제안하였다. 제안된 방식의 실효성을 검증하기 위해 컴퓨터 시뮬레이션을 통해 제안된 방식의 성능을 검증하였다.
Computational analysis of tongue image for health diagnosis

In this thesis, a new health system is introduced based on tongue image analysis. The technologies adopted in this system ranged from tongue image processing algorithms to machine learning applications. The tongue image algorithms used in this work include image segmentation, tongue recognition and tongue image classification. Image segmentation was used to get rid of other unrelated parts, such as lip, face and neck, while keeping the tongue only. Then two recognition methods were applied to check whether the segmented result is a tongue or not. For different tongue patterns, the Support Vector Machine is applied to train a machine learning model and make predictions to classify the tongue into different labeled groups.