Miracle-dz/UniFAR-FTUs huggingface dataset:
New mechanism of the Watson-Crick model of genetic information transmission by example of non-cytokine regulation of hemopoiesis

Our experiment proves conception, that interference of radiation frequency of wave energy hγ≈10 13 Hz of АТР synthesis in plasmatic part of respiratory chain and resonance absorption of this energy frequencies by cellular genetic elements is physical nature of initiating signals to cell growth and cell proliferation through IAK-STAT-Kinase. As a result, it leads to smoothing frequencies of many conformational enzyme-substrate waves, and transmission of molecular signal from plasma membrane inside the nucleus according to the law of Determination L with energy of activation barrier Еact ≈ 0. It is shown, that influence of N-substituted 3-oxipyredine salts on normal and tumor cells results in considerable activation of RNA-polymerases with corresponding amplified duplication of normal RNA-transcripts and reduplication of newly created genetic information as a result of post-transcripts splicing into RNA-dependant DNA-polymerases. Therapeutic effects of the experimental compounds could substitute in clinic rHu G-CSF, rHu EPO, rHu TPO and other known remedies for treatment of anemia and thrombocytopenia of different genesis.
Who moves from fixed-term to open-ended contracts? Youth employment transitions in a segmented labour market

This article explores the career effects of fixed-term employment among Polish youth, taking into account specific legal and institutional arrangements affecting both the incidence of temporary jobs and the chances of moving into more stable employment contracts. The aim of the analysis is twofold. First, it seeks to assess whether temporary contracts serve as a stepping-stone to stable employment or a trap leading to fragmented careers consisting of recurrent short-term jobs. Second, it identifies the factors which increase the chances of successful labour market integration. Both issues are addressed through a quantitative analysis of retrospective career data for a cohort of respondents aged 21–30 from two waves of the Polish Panel Survey (POLPAN), 2008 and 2013. Results suggest that temporary employment is not restricted to entry-level jobs and acts as a trap rather than a stepping-stone. In addition, the opportunities for moving from fixed-term to open-ended contracts appear to have deteriorated over the years. However, gaining early on-the-job experience, especially in occupations involving highly complex tasks, may improve the chances of attaining job stability.
Homeless people’s trait mindfulness and their resilience – a mediation test on the role of inner peace and hope

ABSTRACT The development of resilience is important for homeless people to maintain health and wellbeing. Personal trait mindfulness has received researchers' burgeoning interest regarding its association with one’s resilience. However, very few studies investigate this relationship among homeless people. The current research initiated this exploration and further examined the cognitive (i.e. hopeful thinking) and emotional (i.e. a feeling of inner peace) factors that were assumed to mediate this relationship. The data were collected based on a sample of 172 homeless individuals from a local homeless shelter located in the south-eastern United States. Participants completed a questionnaire that entailed measures of trait mindfulness, resilience, hope, and inner peace. The result of Pearson bivariate correlation revealed that trait mindfulness of homeless people was highly correlated with their resilience. Moreover, a serial mediation model was tested to examine the effects of hope and inner peace on mediating the relationship between trait mindfulness and resilience. The results supported that trait mindfulness of homeless people, through the mediators of hope and inner peace, is conducive to the development of their resilience. The results have unique implications for social service providers to use mindfulness training to build resilience of homeless people.
Complex interactions between the wind and ballistic seed dispersal in Impatiens glandulifera (Royle)

1. A mechanistic understanding of seed dispersal is important for understanding and predicting dispersal patterns and spatial population dynamics. We analysed a mechanistic model for the ballistic dispersal of the widespread invasive plant Impatiens glandulifera. The model deterministically simulates individual seed trajectories, including the interaction between seeds and atmospheric winds. It is fully specified using independently measured plant traits and wind velocities.
Sex differences and temporal trends in aortic dissection: a population-based study of incidence, treatment strategies, and outcome in Swedish patients during 15 years

Abstract Aims As large population-based studies of aortic dissection are lacking, the incidence numbers and knowledge about time-trends and sex differences are uncertain. The objective was to describe incidence, temporal trends and outcome of aortic dissection with particular emphasis on sex differences. Methods and results During the study period 2002–2016, 8057 patients in Sweden were diagnosed with aortic dissection, identified from the National Patient Register and the Cause of Death Register. A total of 5757 (71%) patients were hospitalized, whereas 2300 (29%) patients were deceased without concurrent hospital stay. The annual incidence was 7.2 per 100 000 (9.1 in men and 5.4 in women), decreasing over time in men (P = 0.005). Mean age in the hospitalized patients was 68 years (SD 13), 2080 (36%) were women. Within the first 14 days after onset, 1807 patients (32%) underwent surgical repair. The proportion of surgically treated increased from the 5-year period 2002–2006 to 2012–2016 [27% vs. 35%, odds ratio (OR) 1.61, 95% confidence interval (CI) 1.39–1.86; P < 0.001]. In hospitalized patients, 30-day mortality decreased between the same periods (26% vs. 21%, OR 0.68, 95% CI 0.59–0.80; P < 0.001). Long-term mortality decreased as well (hazard ratio 0.74, 95% CI 0.67–0.82; P < 0.001). Women had higher 30-day mortality than men after acute repair, a sex difference that remained after age adjustment (17% vs. 12%, OR 1.38, 95% CI 1.04–1.82; P = 0.006). Conclusion This population-based study detected a higher incidence of aortic dissection than prior reports, but a decreasing incidence in men. Surgical therapy was increasingly used and with more favourable outcome but was less frequently offered to elderly patients. The sustained sex differences regarding both incidence and outcome require further attention.
Assessing the impact of environmental changes in endemic freshwater fish populations through the temporal analysis of genetic diversity patterns

XI Chapter 1 – General Introduction . 1 1.1 Environmental Impacts and Freshwater Systems . 3 1.2 Natural History Collections. 4 1.3 Microsatellites in Conservation Genetics. 6 1.4 Characterization of the Species – Iberochondrostoma lemmingii . 7 1.5 Thesis Aim . 8 1.6 References . 9 Chapter 2 – Assessing the Impact of Environmental Changes in Endemic Freshwater Fish Populations Through the Temporal Analysis of Genetic Diversity Patterns . 15 2.1. Abstract . 17 2.2. Introduction . 18 2.3. Material and Methods . 21 2.3.1. Sampling and DNA Extraction . 21 2.3.2. Microsatellites Amplification and Allele Scoring . 22 2.3. 3. Genetic Diversity Analysis . 26 2.3. 4. Population Structure Analysis . 27 2.3. 5. Demographic Analysis . 28 2.4. Results . 29 2.4. 1. Loci Amplification, Allele Scoring, Hardy-Weinberg and Linkage Equilibrium . 29 2.4. 2. Genetic Diversity . 30 2.4. 3. Population Structure . 32 2.4. 4. Demographic History . 37 2.5. Discussion . 38 2.5. 1. Continuous Genetic Diversity Through Time . 38 2.5. 2. Increased Population Differentiation Through Time . 39 2.5. 3. Implications for Conservation . 40 2.6. References . 41 Chapter 3 – Final Remarks . 48 3.1. Final Remarks . 50 3.2. References . 50
Multi-Directional Heuristic Search

In the Multi-Agent Meeting problem (MAM), the task is to find a meeting location for multiple agents, as well as a path for each agent to that location. In this paper, we introduce MM*, a Multi-Directional Heuristic Search algorithm that finds the optimal meeting location under different cost functions. MM* generalizes the Meet in the Middle (MM) bidirectional search algorithm to the case of finding an optimal meeting location for multiple agents. Several admissible heuristics are proposed, and experiments demonstrate the benefits of MM*.
Life-history traits of the Northwest European flora: The LEDA database

Abstract An international group of scientists is building a ‘trait base’, an open internet database of life-history traits of the Northwest European flora (LEDA) that can be used as a tool in planning, in nature conservation and restoration, and in other applied research. The species-trait matrix will comprise referenced information under control of an editorial board, for species of the Northwest European flora, combining existing information and additional measurements. The focus will be on 26 plant traits that describe three key features of plant dynamics: persistence, regeneration, and dispersability. Currently 35% of the species-trait matrix has been filled; however, as the LEDA trait base consortium aims to deliver a database as complete as possible, all input from the scientific community is welcome.
Stability of a black eyed pea trypsin/chymotrypsin inhibitor (BTCI)

The stability of BTCI has been investigated as function of pH and temperature, following its inhibitory activity against trypsin. The isolated inhibitor of 9,084 Oa is stable over pH 3 to 12 at 25°C. BTCI showed high thermal stability ranging from 25 to 95°C at pH 3 and 7. However, the protein lost about 20% of its inhibitory activity over 75°C at pH 8.2. The results indicated that BTCI is extremely stable to heat and pH as typical of Bowman-Birk inhibitors.
Functional Studies of SNAP-25 using a knock-out and rescue approach

The neuronal SNARE complex, consisting of SNAP-25, synaptobrevin and syntaxin, is required for presynaptic exocytosis of neurotransmitter-filled vesicles during synaptic transmission. However the SNARE complex undertakes neuronal developmental roles as well. SNAP-25 has been involved in vesicular fusion during axonal outgrowth, synaptic formation and trafficking of glutamate receptors. Its expression is developmentally regulated by alternative splicing from SNAP-25a to SNAP-25b. In GABAergic neurons, SNAP-25 seems to be replaced by SNAP-23, a ubiquitousSNAP-25 homologue, after synaptogenesis. Deletion of SNAP-25 compromises neuronal survival in culture, impeding detailed functional studies. Here, I overcame this difficulty by reintroducing SNAP-25a, SNAP-25b or SNAP-23 using the long-term expression lentiviral system in culture neurons from Snap25 null mice and I was able to dissect the main functions of SNAP-25. I found that that SNAP-25 deficient cultured neurons presented impaired arborization and severe reduction in viability as well as complete arrest of evoked release and reduction in the amplitude and frequency of the spontaneous events. Expression of the SNAP-25 homologues restored neuronal survival, arborization and the properties of spontaneous release. In addition, it rescued evoked release, in both glutamatergic and GABAergic neurons, although SNAP-23 was found to support exclusively asynchronous release. SNAP-25b was superior to SNAP-25a in vesicle priming, which would produce larger releasable pools after synaptic maturation. My results revealed SNAP-25 as key component for neuronal survival and outgrowth, regulation of the synchronous and asynchronous release and spontaneous activity and demonstrate a hierarchical ability of the SNAP-25 homologues to support neuronal function.
A New CNN Approach for Hand Gesture Classification using sEMG Data

In this paper, a new CNN architecture is introduced for classification of six different hand gestures using surface electromyography (EMG) data collected from the forearm. At first, two different deep neural networks produced based on Slow Fusion and Inception models separately. Then, the average of accuracy values and standard deviations were calculated for each type of network. The average accuracy was 80.88% and standard deviation was 0.030 for the Slow Fusion based network. For the Inception based network, average accuracy was 82.64% and standard deviation was 0.028. In addition to these two networks, a new CNN architecture is introduced using Slow fusion and Inception models in combination. The architecture has two parallel Inception modules in parallel. Each parallel module is fed by the half of the 3D feature map. The proposed model slowly fuses the information of the parallel modules throughout the network as in Slow-Fusion architecture. The average accuracy achieved with this model was 83.97% and the standard deviation was 0.027. Despite the small data set, the accuracy had increased with the proposed hybrid model. The smaller standard deviation indicates that it is less affected by variations in the training dataset. Our experimental results show that the proposed method gives the best results among the Slow Fusion based and Inception based models.
Nitrous oxide concentrations in lakes: Variations with depth and time1

Nitrous oxide (N,O) concentrations in several lakes which varied in size, depth, and trophic state were strongly influenced by oxygen concentration. High concentrations of N20 (343 pg N,O*litcr-l) were found in the metalimnion of a eutrophic lake during early spring stratification when hypolimnetic 0, and NO3- were already being depleted. Up to 4 Fg N20* liter-l were observed in oxygenated NO,--containing bottom waters where both nitrification and denitrification were likely occurring.
Community Healing and Resistance Through Storytelling: A Framework to Address Racial Trauma in Africana Communities

Racial trauma, an ongoing consequence of historical trauma, has deleterious effects on the well-being of Africana communities. The psychological literature primarily reflects individual processes in the relationship between racial trauma and healing. Going beyond individualistic approaches, we present a community healing framework informed by multidisciplinary scholarship: Community Healing and Resistance Through Storytelling (C-HeARTS). Three major components of the framework are delineated: (a) justice as both a condition of and an outcome of community healing; (b) culturally syntonic processes (i.e., storytelling and resistance) that direct the renarrating of trauma and act as conduits for transformation; and (c) psychological dimensions (i.e., connectedness, collective memory, and critical consciousness) that promote justice-informed outcomes. In the C-HeARTS framework, community is advanced as an agent of change while centering justice and the important role of cultural practices to facilitate community healing.
«Det er mitt liv detgjelder »

Background: Online support groups carry great potential for cancer patients and have become an increasingly common way of communication. However, more research is needed to learn how participation in such forums may benefit patients. Aim: To understand cancer patients' coping potential as expressed through their descriptions in an online discussion forum. Method: This study is part of a larger study were a selective group of breast and prostate cancer patients communicated in a secure online discussion forum. 711 forum messages were analyzed using qualitative content analysis. Antonovsky's theory of health served as theoretical framework for interpretation of results. Findings: Forum messages revealed: 1) a need to be the central character in one's life's drama 2) a need to be an active participant and mobilise one's strength and 3) a need for storytelling and exchanging of experiences. Conclusion: Expressing oneself through storytelling and exchanging of experiences appears to be an important coping strategy by making the patients' world more comprehensible, manageable and meaningful. It can provide patients with a “sense of coherence” that may make it possible to experience better health. Thus an online discussion forum may have a salutogenic potential.
Robust Haebara Linking for Many Groups in the Case of Partial Invariance

The comparison of group means in item response models constitutes an important issue in empirical research. The present article discusses an extension of Haebara linking by proposing a flexible class of robust linking functions for comparisons of many groups. These robust linking functions are particularly suited to item response data that are generated under partial invariance. In a simulation study, it is shown that the newly proposed robust Haebara linking approach outperforms existing approaches of Haebara linking. In an empirical application using PISA data, it is illustrated that country means can be sensitive to the choice of linking functions.
Heat-induced Gelation of Minced Rainbow Trout (Salmo gairdneri:) Effect of pH, Sodium Chloride and Setting

The structure formation of minced rainbow trout was monitored during heating from 30°C to 85°C by a dynamic rheological method. The maxima of storage modulus (G') were found at 37°C and in the range of 45°C to 60°C. The largest differences in rigidity resulted from seasonal variations. Firmest protein matrix was obtained by using well-fed fish as raw material, by setting the gels at 35°C and using a pH value around 6.1. Sodium chloride in the range 1–2% had little effect on the final rigidity of the minced rainbow trout gels.
Airborne Mesophilic Bacteria at the Ciechocinek Health Resort

The aim of the present study was to determine microbiological air quality in the Ciechocinek health resort and to identify the most common mesophilic bacteria present in the air. Sampling sites were located in the surroundings of inhalators (graduation towers and the “Grzyb” fountain), in recreation areas (promenade, parks), and urban areas. Samples were obtained by the impaction method in a Merck MAS-100 microbial airsampler. Enumeration of mesophilic bacteria was conducted according to the Polish Standard (PN86/Z04111/02). Bacterial strains were identified with appropriate API tests (bioMerieux). Due to the specific microclimate and low levels of microbiological air pollution, Ciechocinek can be considered an excellent upper respiratory tract spa. The lowest numbers of the investigated types of bacteria were found around the open inhalators. In the Ciechocinek area bacteria commonly occurring in air prevailed. Gram-positive bacilli (mainly Bacillus genus) were the most common among the isolated bacteria (53.8% of all strains), and Gram-positive cocci (Staphylococcus, Micrococcus) also were abundant (28%). The least abundant were Gram-negative rods (Pseudomonas, Serratia). Potentially pathogenic species (Pseudomonas aeruginosa, Enterococcus faecium, Aeromonas hydrofila) were found sporadically.
The Ecology of Brood Parasitism in Birds

Birds as brood parasites lay their eggs in the nests of other kinds of birds; these "hosts" incubate and rear the young. In the Old World, cuckoos have long been known as brood parasites. The early Vedic writers of India as well as Aristotle mentioned as common knowledge the fact that cuckoos are reared by other species (42). About 1 % of all bird species are brood parasites, including the honey guides (Indicatoridae), nearly half of the 1 30 species of cuckoos (Cuculidae), two genera of finches (Vidua and Anomalospiza, Ploceidae), five cowbirds (Icteridae), and a duck (Heteronetta atricapilla, Anatidae) (37-42, 9 1-93, 1 14, 1 32, 1 36, 199). No other vertebrate groups with parental care so consistently parasitize other species. [A few freshwater fish do occasionally ( 14). ] Counterparts of the cuckoos are known among insects, of which several groups are specialized for interactions with social insects, ranging from facultative commensalism to an inquilinism close to the cuckoo nexus. Some adult insects as well as immature depend completely on their hosts (4, 202). Most parasitic birds are altricial; their nestlings depend on the host for food. The parasitic duck, however, obtains only protection and warmth from the host and feeds and cares for itself shortly after hatching ( 199).
Zoning the Rate of Pollution in Domestic River Using Spatial Multi - Criteria Evaluation Model

Abstract Surface water, especially rivers, is the most important sources of water supplies for drinking, agricultural and industry use and livelihoods. Controlling the pollution of BalikhlouChai River as one of the most important sources of water supply in Ardabil province in Iran is very significance and vital. In this research, the pollution zoning by using the Spatial Multi-Criteria Evaluation (SMCE) model in BalikhlouChai River was carried out to evaluate the trend of changes in water index and other important parameters by considering the physicochemical, biological, socio-economic and cultural constraints. First of all six stations were selected in the study zone and the sampling was performed over a 12 months period, and then the average of obtained parameters was compared with the standard values of Department of Environment in Iran. The results showed that fecal coliform in most stations and BOD5 in stations 4 and 5, and Nitrate in the stations 4, 5, and 6 were more than standard. Next, the related factors and criteria with the changes in pollution trend in river was identified, weighted and prioritized by the Analytical Network Process (ANP) model. Then the basic maps were prepared and the information layers were incorporated into the SMCE model. Finally, the zoning map of BalikhlouChai River specified in terms of pollution and river health in two contaminated and safe areas in the study basin. According to the results of this study, 3 zones for the safe and 3 zones for the contaminated areas in the study region of river basin were determined which respectively the numerical values of 1, 0.85 and 0.75 for the safe zones and 0.2 and 0.1 and about zero values for the contaminated zones were calculated. The results of quality and quantity zoning indicate that the northeast regions of the study area, including Ardabil City outlet and the Qarasu River basin have gained almost zero value.