Miracle-dz/UniFAR-FTUs huggingface dataset:
Neural crest cells in outflow tract septation of the embryonic chicken heart: Differentiation and apoptosis

The heart consists of cells deriving from the cardiogenic plate and also from extracardiac sources. One of the major extracardiac contributions is given by the neural crest. The differentiation pathway and fate of the neural crest cells in the outflow tract have been followed over a prolonged period during outflow tract septation. We studied the role of the neural crest in remodeling the outflow tract by long‐term cell tracing, differentiation markers and apoptosis.
Association of ferritin with prostate cancer.

PURPOSE Prostate specific antigen (PSA) has been widely used as the unique serum biomarker for the diagnosis and/ or pre-diagnosis of prostate cancer (PCa). However, the diagnostic value of PSA is a subject of ongoing debate owing to its lack of specificity, especially when the PSA level is moderately increased (e.g., 4-10 ng/ml). Thus, we suggest the need for identification of a new biomarker to discriminate PCa cases from benign prostatic hyperplasia (BPH) and normal controls (N). METHODS Urine or tissue samples of PCa patients, BPH patients, and normal controls were systematically collected. The expression of ferritin light chain (FTL) and ferritin heavy chain (FTH) was verified by immunohistochemistry in the tissue. The concentration of urinary ferritin was measured by Access Immunoassay. The level of creatinine in the urine was detected on a HITACHI 7080 system to calculate the ferritin-creatinine ratio (FCR). The data were statistically analyzed using the rank sum test. RESULTS Immunohistochemical characterization of tissues in patients with PCa and BPH was conducted. We found representative immunohistochemical expression of FTL and FTH, with strong staining intensity in PCa and weak staining intensity in BPH. Furthermore, there were differences in urinary FCR among the three groups, with significant differences in the PCa group (134.46±47.01) compared to both the BPH (24.18±3.17, p = 0.009) and control (6.42±0.82, p = 0.003) groups. In contrast, there was no significant difference between the BPH and N groups (p = 0.649). CONCLUSIONS Ferritin is a potential urinary biomarker to discriminate between PCa and BPH patients.
Toying with technology in elementary education

Sponsored by a Miller Faculty Fellowship at Iowa State University, a new course was developed and offered for the first time in the fall semester of 1997. The course is called "Toying with Technology" and is designed to explain the principles behind many of the technological innovations in wide use today. It does this via a collection of hands-on laboratory experiences based upon simple systems constructed out of LEGO and controlled by small computers. These laboratory experiences are designed to lead experimentation, through the use of technology in support of many everyday activities. The initial offering of this course was to elementary education majors. As the course proceeded, it became clear that material appropriate for such majors was also appropriate for the students they would ultimately be teaching. Consequently, emphasis was placed on material appropriate for elementary-level students and a particular approach to teaching such material. This paper describes the development and first offering of the course, highlights some of the lab exercises used, and describes future expansion plans for our technology literacy project.
ASSESSING PSYCHOLOGICAL INJURY IN MOTOR VEHICLE INSURANCE COMPENSATION CLAIMS: VALIDATING A CUSTOMIZED PROTOCOL

of death in our society. Recent figures for road deaths were 3643 in 2004, 4084 in 2003, 4031 in 2002 and 4170 in 2001. But behind this figure for deaths is another, no less important, for those who sustained injuries. In 2004 this was 138,383 and the previous year 150,635, while in 2002 it was 146,917 and in 2001 it was 149,599 (Source: Direction General de Trafico). In sum, the annual total of deaths is around 4000, and that of injured over 145,000. In the wake of each death or injury is irreparable harm, compensation for which is covered by the legislation on Civil Responsibility and Motor Vehicle Insurance (Ley 30/1995, of 8 November; revised text approved by Royal Decree 8/2004, of 29 October). The damages or harm liable for compensation are material, physical and psychological, the last of these being referred to as psychological injury. All injury, in order to be legally considered as such, must be demonstrated. In the psychological context, the National Comorbidity Survey (e.g., Bryant & Harvey, 1995) has identified Post-traumatic Stress Disorder (PTSD) as the primary indication of psychological injury, and as indirect consequences in traffic accident cases, depression and dysthymia (Blanchard & Hickling, 2004). Thus, PTSD must be diagnosed as the direct outcome in the forensic psychological examination, so that where no PTSD is found it cannot be concluded that there is psychological injury, insofar as its co-occurrence with depression or dysthymia must be understood as a confirmation of injury, while if no depression or dysthymia is diagnosed it cannot be inferred that no injury has occurred. In turn, given that this is a medico-legal context, malingering must be considered as a hypothesis (American Psychiatric Association, 2002). The assessment of psychological injury in conjunction with a decision on potential malingering requires a multimethod approach (Rogers, 1997). For measurement within the Spanish legal system, R e g u l a r a r t i c l e s
The Present Status of Endoscopy

Introduced to the field of plastic surgery in the early 1990s, surgical endoscopy has expanded rapidly with applications across the broad range of plastic surgery. Although basic principles and concepts have remained the same, there have been advances in both instrumentation and surgical ingenuity, allowing these broader applications. The numerous applications of the endoscope were reviewed and evaluated. Although some applications such as the endoscopic forehead lift and transaxillary endoscopic augmentation seem to have received general acceptance and are used across a broad spectrum of plastic surgery practices, others such as endoscopic muscle harvest have not gained such widespread acceptance. Also, there are areas such as endoscopic microvascular surgery that await advances in technology and instrumentation.
SERVICE RECOVERY MANAGEMENT: CLOSING THE GAP BETWEEN BEST PRACTICES AND ACTUAL PRACTICES

“Best practice” in service recovery has been well documented in the past 20 years and is familiar to many throughout industry and academia. Nevertheless, overall customer satisfaction after a failure has not improved, and many managers claim their companies cannot respond to and fix recurring problems quickly enough. We therefore explore the apparent gap between best and actual practices in service recovery management. We summarize best practice principles— which we categorize as process recovery, employee recovery, and customer recovery—then illustrate how the tensions among those three discipline-based approaches inhibit a firm’s ability to implement a cohesive service recovery strategy. Successful service recovery management instead requires top management commitment to integration around a “service logic,” fitted to shared values and strategy, as reinforced by the seamless collection and sharing of information and recovery metrics and rewards. This integration can yield “best practice” in service recovery management which research indicates will lead to higher customer satisfaction, higher customer loyalty, and higher profitability.
Molecular determinants for the differential coupling of Gα16 to the melatonin MT1, MT2 and Xenopus Mel1c receptors

The pineal neurohormone melatonin modulates a variety of physiological processes through different receptors. It has recently been reported that the cloned melatonin receptors (MT1, MT2 and Mel1c) exhibit differential abilities to stimulate phospholipase C (PLC) via G16. Here we examined the molecular basis of such differences in melatonin receptor signaling. Coexpression of MT1 or MT2 with the α subunit of G16 (Gα16) allowed COS‐7 cells to accumulate inositol phosphates in response to 2‐iodomelatonin. In contrast, Mel1c did not activate Gα16 even though its expression was demonstrated by radioligand binding and agonist‐induced inhibition of adenylyl cyclase. As Mel1c possesses an exceptionally large C‐terminal tail, we further asked if this structural feature prevented productive coupling to Gα16. Eleven chimeric melatonin or mutant receptors were constructed by swapping all or part of the C‐terminal tail between MT1, MT2 and Mel1c. All chimeras were fully capable of binding 2‐[125I]iodomelatonin and inhibiting adenylyl cyclase. Chimeras containing the full‐length Mel1c tail were incapable of activating Gα16, while those that contained the complete C‐terminal region of either MT1 or MT2 stimulated PLC. Incorporation of the extra portion of the C‐terminal tail of Mel1c to either MT1 or MT2 completely abolished the chimeras' ability to stimulate PLC via Gα16. In contrast, trunc‐ ation of the C‐terminal tail of Mel1c allowed interaction with Gα16. Our results suggest that Gα16 can discern structural differences amid the three melatonin receptors and provide evidence for functional distinction of Mel1c from MT1 and MT2 receptors.
An Empirical Study of Platform and Derivative Product Development Projects

Abstract Many firms now realize the importance of planning product families and product platforms. However, little research addresses planning and execution of different types of projects within a product family platform series. This study investigates project characteristics, development challenges, typical outcomes, and success factors for product development projects at different locations in the product family spectrum. “Platform” projects result in products that initiate a new product family platform for a company. “Derivative” projects result in products consisting of extensions to an existing product family platform. Data on 108 new product development projects from a variety of assembled products industries were collected via a detailed survey and analyzed. Findings indicate that: (1) platform and derivative projects differ in project task characteristics (including the amount of new technology development undertaken and project complexity) and market newness; (2) platform and derivative projects generally do not differ in terms of project success (achievement of project objectives, level of company satisfaction, and perceived customer satisfaction) or smoothness of project execution; (3) both platform and derivative projects generally are executed in similar ways; (4) certain managerial approaches (including contingency planning, project-based evaluation of personnel, and overlap of design and manufacturing engineering) are associated with higher project execution success for both platform and derivative projects; and (5) use of interdependent technologies and novel project objectives are associated with project execution failure for platform projects. The results suggest that firms can continue to employ a single product development management process for both platform and derivative projects, as long as modest customization of the process is made for the given project type. Completely different management processes are not required. In all, the results presented in this article suggest specific managerial actions companies can take to significantly improve product development success.
Physicochemical characterization of drug nanocarriers

Pharmaceutical design has enabled important advances in the prevention, treatment, and diagnosis of diseases. The use of nanotechnology to optimize the delivery of drugs and diagnostic molecules is increasingly receiving attention due to the enhanced efficiency provided by these systems. Understanding the structures of nanocarriers is crucial in elucidating their physical and chemical properties, which greatly influence their behavior in the body at both the molecular and systemic levels. This review was conducted to describe the principles and characteristics of techniques commonly used to elucidate the structures of nanocarriers, with consideration of their size, morphology, surface charge, porosity, crystalline arrangement, and phase. These techniques include X-ray diffraction, small-angle X-ray scattering, dynamic light scattering, zeta potential, polarized light microscopy, transmission electron microscopy, scanning electron microcopy, and porosimetry. Moreover, we describe some of the commonly used nanocarriers (liquid crystals, metal–organic frameworks, silica nanospheres, liposomes, solid lipid nanoparticles, and micelles) and the main aspects of their structures.
On Identity-Based Cryptosystems from Quadratic Residuosity

Three approaches are currently used for devising identity-based encryption schemes. They build on pairings, quadratic residues (QR), and lattices, respectively. Among them, the QR-based scheme proposed by Cocks in 2001 is notable in that it works in standard RSA groups: its security relies on the standard quadratic residuosity assumption. But is has also a number of deficiencies, some of them have been subsequently addressed in follow-up works. Currently, one of the main limitations of Cocks’ scheme resides in its apparent lack of structure. This considerably restricts the range of possible applications. For example, given two Cocks ciphertexts, it is unknown how to evaluate of function thereof. Cocks’ scheme is believed to be non-homomorphic. This paper disproves this conjecture and proposes a constructive method for computing over Cocks ciphertexts. The discovery of the hidden algebraic structure behind Cocks encryption is at the core of the method. It offers a better understanding of Cocks’ scheme. As a further illustration of the importance of the knowledge of the underlying structure, this paper shows how to anonymize Cocks ciphertexts without increasing their size or sacrificing the security. This results for example in the most efficient public-key encryption scheme with keyword search based on the quadratic residuosity.
Role of Cash Management System in Banking Sector

In the wake of the financial crisis, banks around the world have to adapt to a different and rapidly changing business Cash is the life blood of any business. It is very important factor to any orgnisation. It helps to achieve the objectives of the business and helps to carry the smooth working of an orgnisation. The very prominent process in an economy is the cash flow and currency flow within the economy. It has unique assets and most important to quality system to be able to maintain the flow of cash and currency between outlets, Banks and customers. With the changing enviournment of today’s era bank has faced a huge challenge that is change, banks needs to be very careful and updated with the changing standards. To overcome the shrinking deposits, to increase the number of accounts etc. bank has to be updated and come up with the new technique Cash Management Services. Hence the objective of this paper is to study the Role of cash management system in Banking Sector.
Community Health Workers “101” for Primary Care Providers and Other Stakeholders in Health Care Systems

Today's ambulatory care providers face numerous challenges as they try to practice efficient, patient-centered medicine. This article explains how community health workers (CHWs) can be engaged to address many patient- and system-related barriers currently experienced in ambulatory care practices. Community health workers are frontline public health workers who serve as a trusted bridge between community members and health care providers. Among their varied roles, CHWs can educate and support patients in managing their risk factors and diseases and link these patients to needed resources. As shown in this overview (CHW 101), including CHWs as members of multidisciplinary care teams has the potential to strengthen both current and emerging models of health care delivery.
THE COST OF THE MUSE: POETS DIE YOUNG

Although several investigations have found that poets tend to die younger than other types of writers, these studies often do not take into account variables of gender and culture. This study examines 1,987 deceased writers from four different cultures: American, Chinese, Turkish, and Eastern European. Both male and female poets had the shortest life spans of all four types of writers (fiction writers, poets, playwrights, and non-fiction writers), and poets had the shortest life spans in three of the four cultures (and the second shortest life span among Eastern European writers). Possible reasons for the poet's shorter life span are then discussed.
Decentralized caching and coded delivery over Gaussian broadcast channels

A cache-aided K-user Gaussian broadcast channel (BC) is considered. The transmitter has a library of N equal-rate files, from which each user demands one. The impact of the equal-capacity receiver cache memories on the minimum required transmit power to satisfy all user demands is studied. Decentralized caching with uniformly random demands is considered, and both the minimum average power (averaged over all demand combinations) and the minimum peak power (minimum power required to satisfy the worst-case demand combination) are studied. Upper and lower bounds are presented on the minimum required average and peak transmit power as a function of the cache capacity, assuming uncoded cache placement. The gaps between the upper and lower bounds on both the minimum peak and average power values are shown to be relatively small through numerical results, particularly for large cache capacities.
ADAPTIVE SIGNIFICANCE OF IPOMOPSIS AGGREGATA NECTAR PRODUCTION: OBSERVATION AND EXPERIMENT IN THE FIELD

Production of floral nectar is generally thought to be an adaptation that increases plant fitness by altering pollinator behavior, and therefore pollination success. To test this hypothesis, I investigated the effects of floral nectar production rate on pollination success of the hermaphroditic plant Ipomopsis aggregata (Polemoniaceae). Success through male function (estimated by the export of fluorescent dyes) was significantly greater for plants with naturally high nectar production rates than for nearby plants with low nectar production rates, whereas success through female function (receipt of fluorescent dye) was unrelated to nectar production rate. Experimental addition of artificial nectar also produced a significant increase in male function success and no increase in several estimates of female function success. Observations confirmed that hummingbirds probed a larger proportion of flowers on plants that received supplemental nectar, as they do in response to natural variation in nectar production. The concordance of results across these observational and experimental studies indicates that nectar production acts primarily to increase pollination success through male function for this species.
Innovation Effects on Customer Trust: The Case of Pasargad Bank

Customer satisfaction and trust as the main issues are considered as the most important parameter which effect life cycle of an organization, for the reason that all organizations, manufacturing concerns and service companies attempt to achieve customer satisfaction, so it is clear that the evaluation of effectiveness of innovation relies on customer trust. So in this article we try to study the effective factors which effect on customer trust and innovation effects on it and propose a model to identify innovation effectiveness on customer trust. In this research we compile information in this case via related experts with questionnaires and by analyzing the questionnaires data, study the employee’s innovation and creative environment in organization shall affect the satisfaction of special customers.
Green Supplier Selection and Assessment in GSCM Using Analytic Hierarchy Process (AHP) for Information and Electronic Industry

Taiwan plays a very important role in the production and outsourcing for the OEMs and ODMs in the global supply chain system of the information and electronic industry. In the recent few years, two of the most important environmental protection directives of WEEE, and RoHS in the European Union have greatly influenced the information and electronic industry. Therefore, many OEMs/ODMs want to help their suppliers to achieve a better environmental performance in supply chains. This study focuses on green supplier selection and assessment in green supply chain management (GSCM) through various criteria and sub-criteria from literature reviews and Delphi experts' opinions, and then uses the AHP method to set up a green supplier rating system that can be applied to the information and electronic industry of Taiwan. Furthermore, this study can provide the evaluation model with the industry in implementing the best GSCM practices. The research results indicate that the supply chain base such as cost, quality, delivery schedule, and service performance is the most critical assessment criteria in the green supplier selection. Green material selection, ISO-14001 certification, and suppliers' credit problems are also main evaluation sub-criteria. The internal management system also plays an important factor because the authorization by top management affects the willingness to get involved in the GSCM.
Metal nanogrids, nanowires, and nanofibers for transparent electrodes

Metals possess the highest conductivity among all room-temperature materials; however, ultrathin metal films demonstrate decent optical transparency but poor sheet conductance due to electron scattering from the surface and grain boundaries. This article discusses engineered metal nanostructures in the form of nanogrids, nanowires, or continuous nanofibers as efficient transparent and conductive electrodes. Metal nanogrids are discussed, as they represent an excellent platform for understanding the fundamental science. Progress toward low-cost, nano-ink-based printed silver nanowire electrodes, including silver nanowire synthesis, film fabrication, wire-wire junction resistance, optoelectronic properties, and stability, are also discussed. Another important factor for low-cost application is to use earth-abundant materials. Copper-based nanowires and nanofibers are discussed in this context. Examples of device integrations of these materials are also given. Such metal nanostructure-based transparent electrodes are particularly attractive for solar cell applications.
Guided Wave Optical MEMS Pressure Sensor

Guided wave optics in combination with micro-machining technology offer immense potential for sensor applications. In this paper we analyse an guided wave optics based MEMS pressure sensor consisting of a Mach-Zehnder interferometer whose sensing arm is over the edge of a bulk micromachined silicon diaphragm. We compare this sensor utilising the elasto-optic effect with the conventional piezo-resistive and capacitive micromachined pressure sensors in terms of their sensitivities. This MOEM pressure sensor is found to be superior to the conventional ones. This sensor can be used for blood pressure monitoring, precision instrumentation, aerospace propulsion application with suitable design parameters
Frequent impairment of the spindle assembly checkpoint in hepatocellular carcinoma

Chromosomal instability (CI) leading to aneuploidy is one form of genetic instability, a characteristic feature of various types of cancers. Recent work has suggested that CI can be induced by a spindle assembly checkpoint defect. The aim of the current study was to determine the frequency of a defect of the checkpoint in hepatocellular carcinoma (HCC) and to establish whether alterations of genes encoding the checkpoint were associated with CI in HCC.