Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effectiveness of Mobile Learning: A Critical Review of Empirical Literature

ワイヤレスモバイル技術は多様な教育状況の中に取り入れられてきた。 モバイル学習の長所は学習者 がいつでもどこでも学習を可能にすることであり,多くの研究者は学習の新しい変革の可能性を信じて いる。 しかし,いくつかの研究は学習者が学習にモバイルデバイスを使うことを好まないことに加え, 技術の限界について批判している。 モバイル学習への疑問があったとしてもモバイル学習をそれぞれの フィールドで実践してきた多様な研究は肯定的な結果を報告している。 本論文は,これらのモバイル学 習の効果を評価してきた実証研究を概説する。 その結果,モバイル学習は相互作用を促進し,学習成果 を高め,クラスの管理を支援し,非公式学習に積極的に使われることが示された。 この結果に基づき, モバイル学習の可能性と将来の挑戦について議論した。 Wireless mobile technology has been adopted in a various education contexts. The advantage of mobile learning is that it allows learners to study at anytime and anywhere. Researchers believe that it heralds a new revolution on learning. However, some studies criticize this facility from the point of view of technical limitation, as well as learners’ unwillingness to use mobile devices in their learning. Even though there have been doubts about mobile learning, researches on the application of activity which apply mobile learning in various fields have reported positive results. This paper reviews the empirical studies which have evaluated mobile learning’s effectiveness. Results indicate that mobile learning facilitates interaction, improves learning performance, supports class management and is actively employed for the purpose of informal learning. Based on these results, the potential of mobile learning and future challenges are discussed. モバイル学習の効果―実証研究文献の概説― The Effectiveness of Mobile Learning: A Critical Review of Empirical Literature 崔 淑敬 CHOI, Sook-Kyoung ● 国際基督教大学大学院アーツ・サイエンス研究科 Graduate School of Arts and Sciences, International Christian University
Pulmonary function tests and diffusing capacity in patients with systemic sclerosis

Piotr Siergiejko, Grzegorz Siergiejko, Justyna Fryc, Zenon Siergiejko, Maciej Kaczmarski, Stanisław Sierakowski, Ewa Gińdzieńska-Sieśkiewicz 1Klinika Reumatologii i Chorób Wewnętrznych Uniwersytetu Medycznego w Białymstoku 2Klinika Pediatrii, Gastroenterologii i Alergologii Dziecięcej Uniwersytetu Medycznego w Białymstoku 3Samodzielna Pracownia Diagnostyki Układu Oddechowego i Bronchoskopii Uniwersytetu Medycznego w Białymstoku
Systemic absortion and adverse effects of topical ocular use of ketorolac tromethamine and sodium diclofenac in New Zealand rabbits for 90 days

Faculdade de Medicina Veterinária ˗ Universidade Federal do Rio Grande do Sul ˗ Porto Alegre, RS Programa de pós-graduação ˗ Universidade Federal do Rio Grande do Sul ˗ Porto Alegre, RS Programa de pós-graduação ˗ Universidade Federal do Paraná ˗ Curitiba, PR Universidade Federal de Ciências da Saúde de Porto Alegre ˗ Porto Alegre, RS Programa de graduação ˗ Universidade Federal de Ciências da Saúde de Porto Alegre ˗ Porto Alegre, RS
Dysregulations of Functional RNA Modifications in Cancer, Cancer Stemness and Cancer Therapeutics

More than a hundred chemical modifications in coding and non-coding RNAs have been identified so far. Many of the RNA modifications are dynamic and reversible, playing critical roles in gene regulation at the posttranscriptional level. The abundance and functions of RNA modifications are controlled mainly by the modification regulatory proteins: writers, erasers and readers. Modified RNA bases and their regulators form intricate networks which are associated with a vast array of diverse biological functions. RNA modifications are not only essential for maintaining the stability and structural integrity of the RNA molecules themselves, they are also associated with the functional outcomes and phenotypic attributes of cells. In addition to their normal biological roles, many of the RNA modifications also play important roles in various diseases particularly in cancer as evidenced that the modified RNA transcripts and their regulatory proteins are aberrantly expressed in many cancer types. This review will first summarize the most commonly reported RNA modifications and their regulations, followed by discussing recent studies on the roles of RNA modifications in cancer, cancer stemness as wells as functional RNA modification machinery as potential cancer therapeutic targets. It is concluded that, while advanced technologies have uncovered the contributions of many of RNA modifications in cancer, the underlying mechanisms are still poorly understood. Moreover, whether and how environmental pollutants, important cancer etiological factors, trigger abnormal RNA modifications and their roles in environmental carcinogenesis remain largely unknown. Further studies are needed to elucidate the mechanism of how RNA modifications promote cell malignant transformation and generation of cancer stem cells, which will lead to the development of new strategies for cancer prevention and treatment.
Is perioperative goal-directed therapy able to reduce surgical complications in different surgical settings? A meta-analytic study

IntroductionGoal directed therapy (GDT) is a method aiming at optimizing doses and timing of fluids, inotropes and vasopressors, through monitoring of cardiac output and other basic hemodynamic parameters. Several meta-analyses confirm that GDT can reduce postoperative complications in high risk patients, and a recent trial suggests its significant effect also in low-moderate risk patients. The aim of the present meta-analysis is to investigate the effect of GDT on postoperative complications, in both high and low risk patients. Moreover, we stratified the effect of GDT in different kind of surgical procedures.MethodsRandomized controlled trials (RCTs) on perioperative GDT in adult surgical patients were included. The primary outcome measure was complications, defined as number of patients with a least one postoperative complication. A subgroup-analysis was also performed including RCTs with a mortality rate in control group <10%, and considering the kind of surgery: major abdominal (including also major vascular), only vascular, only orthopedic surgery and so on. Meta-analytic techniques (analysis software RevMan, version 5.3.5, Cochrane Collaboration, Oxford, England, UK) were used to combine studies using odds ratios (ORs) and 95% confidence intervals (CIs). ResultsIn 47 RCTs, 2329 patients developed at least one complication: 1030 out of 2781 (37%) were randomized to perioperative GDT, and 1299 out of 2772 (47%) were randomized to control. Pooled OR was 0.58 and 95% CI was 0.47-0.70. The sensitivity analysis confirmed main result. The subgroup analysis including only studies in which the mortality rate in the control group was higher than 10% showed significant results (OR 0.51, 95% CI 0.35-0.74, p=0.004, 10 RCTs), as well as a statistical significant effect was observed in those RCTs with a mortality rate in control group <10% (OR 0.59, 95% CI 0.47-0.74, p<0.0001, 37 RCTs). The subgroup analysis enrolling major abdominal patients showed a significant result (OR 0.69, 95% CI 0.57-0.83,p <0.0001, 29 RCTs, 3881 patients) as well as a significant effect was observed in those RCTs enrolling exclusively orthopedic (OR 0.48, 95% CI 0.30-0.79,p=0.004, 6 RCTs, 501 patients) and neurosurgical procedures (OR 0.40, 95% CI 0.21-0.78, p=0.008, 2 RCTs, 208 patients). ConclusionsThe present meta-analysis suggests that GDT can reduce postoperative complication rate in high risk as well as in low risk patients. Moreover, the beneficial effect of GDT on postoperative morbidity is significant on major abdominal, orthopedic and neurosurgical procedures. However, heterogeneity was found in some subgroups, reducing the strength of the results. Several well-designed RCTs are needed to further explore the effect of GDT in low risk patient and in different kind of surgeries.
A Novel Approach for Integrating Best Evidence and Patient Preferences into Treatment Recommendations for Rheumatoid Arthritis

To develop a treatment recommendation we must first critically appraise and summarize the evidence, then decide how to weigh the necessary trade-offs between the benefits and harms. GRADE, which is becoming the standard for developing treatment recommendations, recommends that patients’ preferences should be explicitly considered when making these tradeoffs, but methods for doing this quantitatively are lacking. The aim of this thesis was to develop a quantitative approach for combining comparative effectiveness research and patients’ preferences, and apply it to inform treatment recommendations for early rheumatoid arthritis. In the first study, we performed a Bayesian network meta-analysis of 150 randomized controlled trials to compare the benefits and harms of treatment options for early rheumatoid arthritis. In the second paper we used a discrete-choice experiment to measure the relative importance of the major outcomes from the network meta-analysis as well as other issues relevant to the decision (dosing, rare risks) in patients with early rheumatoid arthritis. For the final paper we used a Bayesian framework to combine the data from the network-meta-analysis and the discrete-choice
Solar radiative forcing of aerosol particles near the Taklimakan desert during the Dust Aerosol Observation-Kashi campaign in Spring 2019

Abstract. The Taklimakan desert is a main and continuous source of Asian dust particles causing a significant direct aerosol solar radiative forcing (ASRF). In order to improve the accuracy of the estimation of dust radiative forcing effects, the Dust Aerosol Observation-Kashi (DAO-K) campaign was carried out near the Taklimakan desert in April 2019. The objective of the campaign is to provide comprehensive parameters such as: dust optical and microphysical properties, vertical distribution and surface albedo, for the calculation of ASRF. The measurements were employed in radiative transfer (RT) simulations and the estimations are improved by considering the actual measured atmospheric profiles and diurnal variations of land surface albedo in addition to reliable aerosol parameters. The RT model estimates the ASRF results in average daily mean cooling effects of −19 W m−2 at the top of atmosphere and −36 W m−2 at the bottom of atmosphere during the DAO-K campaign. The Weather Research and Forecasting model with Chemistry (WRF-Chem) with assimilations of the aerosol optical depth and PM2.5 and PM10 concentrations measurements is prone to overestimate the radiative forcing effects of dust aerosols. The percent difference of daily mean ASRF between the two simulations are greater than 50 % in heavy dust episode. Ground-based observations of downward irradiances have validated that the RT simulations are in good agreement with simultaneous observations, whereas the WRF-Chem estimations exhibit obvious discrepancy with these independent measurements. Data assimilations can partly reduce the discrepancy, but there is still room for improving the WRF-Chem simulation of dust aerosol radiative forcing.
Bilateral Haptic Collaboration for Human-Robot Cooperative Tasks

The aim of this letter is to introduce the concept of bilateral haptic cooperation as a novel paradigm for human-robot cooperative tasks. The approach is demonstrated with a system composed of a soft gripper and a wearable interface. The soft gripper, called CoGripper, has been designed to guarantee a safe interaction giving the possibility to the operator to reconfigure the device according to the object to be grasped. The wearable interface is used to control the open/close motion of the gripper and to feedback information about important task parameters, e.g., the grasp tightness. The result is a bilateral haptic collaboration where human and robot bidirectionally communicate through the interface. The user interaction with the system is extremely intuitive and simple. We performed three user studies to prove the effectiveness of bilateral haptic collaboration involving ten subjects. Results confirmed that the use of the wearable interface reduces the time to accomplish a cooperative task and enables a better control of the grasp tightness.
Incidence of injuries and illnesses among Sabah athletes during SUKMA XIX 2018

This is a study on the prevalence of injuries and illnesses among Sabah SUKMA athletes 2018. This is a retrospective study on injuries and illnesses seen among Sabah athlete who participating in SUKMA 2018 using standardized data registry. Incidence of injury and illness is 16.27 and 16.74 per 100 athletes respectively. Combat sports showed the highest incidence of injuries (45%) mainly involving head and neck region in martial arts event (Muay Thai). Commonly occurring injuries involved were muscle strains and ligament sprains. Concussion rate was 1.85 per 100 full contact athletes. Time loss percentage was 1.4%. The only important illness reported was an isolated case of mumps. There was a high number of injuries in combat sports. There were no report of severe injuries or severe concussions. This could be due to the strict implementation of protective gear during competition. Concussion rate was lower compared to many international studies. Muscle strains was seen more in high speed sprinting and kicking athletes. Contact tracing was activated and no reported Mumps outbreaks in Sabah. There is a need for athlete to learn prevention strategies in combat sports and screening of athlete for infectious diseases prior to participation in national or international sporting event.
Protective Effect of Dietary Vitamin E (α Tocopherol) on Artemisinin Induced Oxidative Liver Tissue Damage in Rats

This experiment was designed to study the effects of oral administration of artemether which is the most rapid-acting class of antimalarial drugs and the possible protective effect of vitamin E taken with it on the liver of albino rats. A total of twenty-four adult male albino rats were used in this study and were divided into four groups. Group one served as a control and rats in group two exp sed to oral intake of artemether daily for fifteen days. The third and fourth groups treated with artemether plus low and high doses of vit amin E respectively. At the end of the experiment, the rats were sacrificed, and the livers were obtained and processed for histological, biochemica l and stat stical studies. Histological study of the hepatocytes of rats exposed to artemether showed nearly complete disintegration of mos t cellular contents except few numbers of mitochondria and rough endoplasmic reticulum. Also, the cytoplasm of these cells had few lysosomes, many vacuoles and irregular nuclei with abnormal distribution of chromatin and were shown. The hepatic sinusoids were dilated and filled with blo od and vacuoles and bile ductules were abnormal in its structure. Treatment with low and high doses of vitamin E in concomitant with artemether ameliorated the hepatic histopathological lesions and its parenchyma attained nearly normal structure. As far as biochemical changes, alanine a minotransferase (ALT) and aspartate aminotransferase (AST) in rats treated with artemether were significantly elevated as compared to the contr ol. Superoxide dismutase (SOD) and malondialdehyde (MDA) levels were significantly increased in the liver in rats treated with artemether. How ver, vitamin E ameliorated the rise in ALT and AST with decreased MDA concentration and levels of SOD as compared to the corresponding artem ether group values. Results of the present suggest that artemether has a harmful and stressful effect on hepatic tissue and the treatment w ith vita in E may alleviate this toxicity.
Influence of Intellectual/Emotional/Spiritual Intelligence, Independence, and Tri Hita Karana on Auditor Performance

Auditor performance is the result of work rendered in carrying out one’s duties within a certain period of time. The quality of auditing is improved if the auditor shows good performance. The aim of this research is to determine how intellectual/emotional/spiritual intelligence, independence, and the culture of Tri Hita Karana affect auditor performance in public accounting firms in Bali. This research was conducted in seven public accountant firms in Bali and questionnaires were used to collect the data. Purposive sampling was employed to determine the sample, and multiple linear regression was applied as a technique of analysis. This research contributes to the literature as it considers Tri Hita Karana as a factor that affects auditor performance. Hopefully, this research can give guidance to public accounting firms in terms of how intellectual/emotional/spiritual intelligence, independence, and Tri Hita Karana influence auditor performance. Keywords: Tri Hita Karana, auditor, intelligence, independence
Enzymes activities in juveniles and adults of Clarias gariepinus reared in earthen ponds and concrete tanks

Clarias gariepinus is the most commonly cultivated fish species in Nigeria, making the country the largest producer in Africa and third in the world, after Thailand and Indonesia. Level of enzyme activities in the plasma of Clarias gariepinus were used to detect tissue damage caused by stress as a result of poor management practices. Sixty-four blood samples were collected from juveniles and adults of catfish reared in six randomly selected fish farms in Lagos State and analyzed with Randox test kits. Results obtained indicated that alkaline phosphatase (ALP), alanine transaminase (ALT), and aspartate transaminase (AST) were significantly elevated (p<0.05) in experimental fish farms when compared to control farms. The study established that amino transaminase and aspartate amino transaminase were higher in fish reared in earthen ponds than concrete tanks as a result of stress, thus indicating renalhepatic malfunctions.
Acoustic Study of Tone 3 Sandhi in Beijing and Taiwan Mandarin

Studies on Mandarin tone sandhi have focused on Beijing Mandarin. Taiwan has been politically separated from mainland China since 1949, but it is not known if tone sandhi in Taiwan Mandarin displays different patterns or characteristics. However, there has been no comparative study to investigate if Beijing Mandarin and Taiwan Mandarin display the same tone sandhi pattern. This study aims to fill this gap by comparing Beijing and Taiwan Mandarin through a productive experiment to examine acoustic differences between sandhied tone 3 and lexical tone 2. The results indicate that tone 3 sandhi among Mandarin dialects is not a homogeneous category, but displays a graded phenomenon of a categorical change and tonal reduction. The experimental evidence shows that acoustic difference between sandhied tone 3 and lexical tone 2 is larger in Beijing Mandarin than that in Taiwan Mandarin. Gender effects are also detected and acoustic difference in female samples is consistently larger than that in male samples across Beijing and Taiwan Mandarin. The findings suggest that the third tone sandhi in Beijing Mandarin is more like a categorical change (i.e., changed to lexical tone 2) whereas the sandhi in Taiwan Mandarin is more like a tonal reduction.
Internet of Things-Based Steam Pump Motor Protection Due to Voltage Unbalance

PLTGU is a gas and steam power plant, producing electrical energy of 3x526 MW. The PLTGU generation process has several supporting components, one of which is a three-phase induction motor. It requires a balanced three-phase supply voltage in its operation. The problem that frequently occurs is unbalanced voltage supply, causing an imbalance of current going to the motor stator, if not directly corrected. It causes a high temperature on the motor, possible to cause a fire. Based on the problems, a system for monitoring the protection of steam pump motorcycles due to voltage unbalance based on the Internet of Things is designed. It used a 1-phase AC Adapter voltage sensor, a current sensor SCT-013, an Arduino Uno as the processor, and a web to display the system. The test results showed that the sensor could work well. It could read voltage with an error percentage not exceeding 1%. The percentage error of the current sensor SCT-013 was 5.15%, but the value difference between the sensor and the Avo meter was 0.01. The system was displayed on the web to make to monitor the motor condition more easily
Comparative study of Bandpass filters based on periodic structures in SIW technology

In this work, the study of two different topologies of S-band band-pass filters based on periodic structures in substrate integrated waveguide (SIW) technology is theoretical and experimentally addressed. The first topology consists of periodic rectangular perforations of the SIW substrate. In this filter topology, the lower cutoff frequency is determined by the cutoff frequency of the first Floquet mode of the periodic structure, while the upper cutoff frequency and the rejection band are conditioned by its first band-gap. The second topology consists of a periodic array of square complementary split-ring resonators (CSRRs) etched on the waveguide surface. In this case, the use of subwavelength resonators with evanescent-wave transmission leads to a much smaller filter, given that the pass-band is below the cutoff frequency of the waveguide. The effect of the different dimensions of the unit cell in the filters characteristics (lower cutoff frequency, pass-band, and rejection-band associated to the first band-gap of the periodic structure) is analyzed through the dispersion diagram of the periodic cell. Finally, two band-pass filters based on each topology have been designed and built, showing in both cases good matching and low insertion loss in the pass-band, and a deep rejection band.
Derin ¨O˘grenme Modellerinde ˙Izge Tabanlı Hata Konumlandırma

Artiﬁcial Neural Networks (ANNs) are increasingly deployed in safety-critical applications including autonomous vehicles and medical diagnostics. To avoid unexpected ANN behaviour and provide evidence for their trustworthy operation, ANNs should be thoroughly tested. In this study, representing ANNs with a programming language such as Java, enabled us to utilize software engineering tools for comprehensive testing of ANNs. Inspired by fault localization in software, the whitebox ANN testing approach that we presented in our paper, establishes the hit spectrum of neurons and identify suspicious neurons which are responsible for inadequate ANN performance. Moreover, we also modiﬁed original inputs to synthesize adversarial inputs that increase activation values of suspicious neurons
Art as Technique

If we start to examine the general laws of perception, we see that as perception becomes habitual, it becomes automatic. Thus, for example, all of our habits retreat into the area of the unconsciously automatic; if one remembers the sensations of holding a pen or of speaking in a foreign language for the first time and compares that with his feeling at performing the action for the ten thousandth time, he will agree with us. Such habituation explains the principles by which, in ordinary speech, we leave phrases unfinished and words half expressed. In this process, ideally realized in algebra, things are replaced by symbols. Complete words are not expressed in rapid speech; their initial sounds are barely perceived. Alexander Pogodin offers the example of a boy considering the sentence "The Swiss mountains are beautiful" in the form of a series of letters: T, S, m, a, b. [1]