Miracle-dz/UniFAR-FTUs huggingface dataset:
Phase Recognition from Power Traces of HPC Workloads

Prior work has shown that power consumption traces of HPC workloads exhibit distinctive statistical characteristics, which allows the workload that generated a given power trace to be inferred with high accuracy. However, these power signatures apply to the entire power trace, with no ability to break it down further into phases or to recognize novel combinations of known workloads. In this work, we propose and evaluate a mechanism for partitioning a power trace into phases and matching each phase to a known kernel or workload. We evaluate this technique on a set of 388 power traces collected from 21 benchmarks, including CPU-intensive system stressors; the NAS Parallel Benchmarks; and Mahout data analytics workloads. Our technique is able to, on average, attribute 78% of the points in a concatenated trace to the correct kernel.
Hamiltonian Magnetohydrodynamics: Lagrangian, Eulerian, and Dynamically Accessible Stability -- Examples with Translation Symmetry

Because different constraints are imposed, stability conditions for dissipationless fluids and magnetofluids may take different forms when derived within the Lagrangian, Eulerian (energy-Casimir), or dynamical accessible frameworks. This is in particular the case when flows are present. These differences are explored explicitly by working out in detail two magnetohydrodynamic examples: convection against gravity in a stratified fluid and translationally invariant perturbations of a rotating magnetized plasma pinch. In this second example we show in explicit form how to perform the time-dependent relabeling introduced in Andreussi {\it et al.}\ [Phys.\ Plasmas {\bf20}, 092104 (2013)] that makes it possible to reformulate Eulerian equilibria with flows as Lagrangian equilibria in the relabeled variables. The procedures detailed in the present article provide a paradigm that can be applied to more general plasma configurations and in addition extended to more general plasma descriptions where dissipation is absent.
Characterization of a novel β-l-arabinofuranosidase in Bifidobacterium longum. FUNCTIONAL ELUCIDATION OF A DUF1680 FAMILY MEMBER.

Kiyotaka Fujita, Yukari Takashi, Eriko Obuchi, Kanefumi Kitahara, and Toshihiko Suganuma This article has been withdrawn by the authors. In the original manuscript, the results of E338A and E366A mutants were reversed. We transformed Escherichia coli BL21 ( DE3) cells with the E366A plasmid instead of the E338A plasmid when sample tubes were switched inadvertently. The correct E338A and E366A mutants were expressed, purified, and characterized again. The results showed that Glu-338, and not Glu-366, is critical for catalytic activity. We wish to withdraw the manuscript and submit a corrected manuscript. We apologize for any inconvenience caused by this error. THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 288, NO. 42, p. 30502, October 18, 2013 © 2013 by The American Society for Biochemistry and Molecular Biology, Inc. Published in the U.S.A.
Landmarking and Segmentation of 3D CT Images

Segmentation and landmarking of computed tomographic (CT) images of pediatric patients are important and useful in computer-aided diagnosis (CAD), treatment planning, and objective analysis of normal as well as pathological regions. Identification and segmentation of organs and tissues in the presence of tumors are difficult. Automatic segmentation of the primary tumor mass in neuroblastoma could facilitate reproducible and objective analysis of the tumor's tissue composition, shape, and size. However, due to the heterogeneous tissue composition of the neuroblastic tumor, ranging from low-attenuation necrosis to high-attenuation calcification, segmentation of the tumor mass is a challenging problem. In this context, methods are described in this book for identification and segmentation of several abdominal and thoracic landmarks to assist in the segmentation of neuroblastic tumors in pediatric CT images. Methods to identify and segment automatically the peripheral artifacts and tissu s, the rib structure, the vertebral column, the spinal canal, the diaphragm, and the pelvic surface are described. Techniques are also presented to evaluate quantitatively the results of segmentation of the vertebral column, the spinal canal, the diaphragm, and the pelvic girdle by comparing with the results of independent manual segmentation performed by a radiologist. The use of the landmarks and removal of several tissues and organs are shown to assist in limiting the scope of the tumor segmentation process to the abdomen, to lead to the reduction of the false-positive error, and to improve the result of segmentation of neuroblastic tumors. Table of Contents: Introduction to Medical Image Analysis / Image Segmentation / Experimental Design and Database / Ribs, Vertebral Column, and Spinal Canal / Delineation of the Diaphragm / Delineation of the Pelvic Girdle / Application of Landmarking / Concluding Remarks
A Brief Introduction to Structural Equation Models

Over the past two decades there has been a rapid increase in the use of what have come to be known as structural equation models, covariance structure models or LISREL models. These models describe the measurement and causal structure of a set of observed variables in terms of a system of simultaneous linear equations which summarise and encapsulate the assumptions of some prespecified conceptual model of the measurement and causal structure of the observed variables. Applications of these methods may be found in many areas including Economics, Psychology, Sociology and Behavioral Genetics. At the same time, the use of these methods for analysing epidemiological data has been limited and, in particular, the full potential for methods of structural equation modelling in the analysis of child psychiatric epidemiological data has yet to be realised. In part, this situation may reflect the fact that many epidemiologists, whilst being aware of structural equation modelling techniques, are unsure about the logic of these methods and how they are applied in practice. The major aim of this chapter is to present an introductory and user friendly account of the logic and application of structural equation modelling methods with this account being aimed at a perceived audience of epidemiologists and analysts who are aware of structural equation modelling techniques but who may be unsure about the application of these methods. For this reason the chapter is presented at an introductory level and presents only a limited account of the formal mathematical and statistical foundations of the method. This does not, however, imply that an understanding of the mathematical and statistical foundations of structural equation models can be ignored and, indeed, the effective application of these methods does require that the user understand these issues, and particularly issues relating to model estimation, model identification and model testing.
ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA.

An electron microscopic study of cerebral biopsy specumens from 3 cases of Alzheimer's presenile dementia has revealed several points of interest. The two major findings have to do with the neurofibrillary tangles and senile plaques which are the characteristic features of this disease. It will be shown that the former are made up of large clusters of fine neurofibrils, while plaques have as their fundamental substance a different sort of filamentous material which is structurally identical to amyloid. Also noteworthy are certain myelin distortions suggestive of primary demyelinization; and a striking, although rare, endothelial change by which lipid-like material passes through the walls of small vessels to enter the lumen. well preserved microscopically and there was only minimal gliosis. Bodian preparations revealed numerous intraneuronal, coarse neurofibrillary tangles. Many senile plaques were also found. They were composed of argentophilic fibers and granules. Core material was poorly demonstrated. The pathologic diagnosis was Alzheimer's presenile dementia.
A reduced-complexity implementation of differential detection for continuous phase modulation in FPGAs

An implement of demodulation for continuous phase modulation is proposed using reduced-complexity method in FPGAs. Viterbi algorithm is implemented to perform sequence correlation and maximum likelihood sequence estimate without reducing states, at the same time a parallel and serial matched filter structure to perform 4096-state correlation. Simulation of the received performance show that the proposed method has reduced complexity without deterioration of the performance.
Social overlapping community-aware neighbor discovery for D2D communications

Because there are multiple social attributes of D2D devices, the accurate perception of these attributes can significantly enhance the neighbor discovery capability of D2D devices in cellular systems and further improve the efficiency of D2D communications. In this article, an accurate detection method of overlapping communities for D2D communications is proposed. By dynamically estimating the roles of overlapping community users in various communities, the corresponding beacon detection rates can be identified. Furthermore, the beacon detection rates can be dynamically adjusted according to the connection status of other intra-community and inter-community users to improve the system energy efficiency and neighbor discovery rates. Simulation results show that the proposed social overlapping community-aware (SOCA) neighbor discovery method for D2D communications can effectively improve system performance including both the neighbor discovery rate and data delivery ratio.
Compact and High-Isolation Diplexer Using Dual-Mode Stub-Loaded Resonators

A novel compact microstrip diplexer for UMTS and WCDMA system is proposed in this letter. The diplexer is mainly composed of three dual-mode stub-loaded microstrip resonators. Two resonant modes of a stub-loaded resonator work together with one mode produced by the common stub-loaded resonator to form a passband or operating band of the proposed diplexer. Extensive study is then conducted on coupling scheme involved in various parts of the diplexer. In particular, the resonance of a resonator is employed to create a desired transmission zero in the stopband, thus improving the isolation between two passbands. The proposed diplexer is in final fabricated and measured. A good agreement between EM simulated and measured results evidently validates the proposed methodology.
Electrical and optical characteristics of high power vertical GaN light-emitting diodes on Si substrates

High power vertical GaN-based light-emitting diodes (LEDs) on Si substrates are fabricated by wafer bonding and laser lift-off (LLO) technique. The GaN-based LEDs are grown on sapphire (0001) substrates by metalorganic chemical vapour deposition (MOCVD). GaN-based LEDs are joined to Si receptor substrates by Sn/Au fusion bonding at the temperature of 300 °C in flowing nitrogen ambient. KrF excimer laser with 400mJ/cm2 energy density is used to irradiate GaN-based LEDs from transparent sapphire substrates to separate the samples from sapphire, forming GaN-based LEDs/Sn/Au/Si structure. Using the samples grown on the same wafer, the electrical and optical characteristics of the GaN-based LEDs on sapphire and on Si are investigated. At 20mA, the forward voltages of GaN-based LEDs on Si and sapphire are 3.1V and 3.3V respectively. At high operation current 110mA, the I-V characteristic of vertical strcture GaN-based LEDs on Si can be improved much more greatly. The light output power of GaN-based LEDs on Si keeps increasing up to 560mA without any power saturation.
An all-sky support vector machine selection of WISE YSO candidates

We explored the AllWISE catalogue of the Wide-field Infrared Survey Explorer mission and identified Young Stellar Object candidates. Reliable 2MASS and WISE photometric data combined with Planck dust opacity values were used to build our dataset and to find the best classification scheme. A sophisticated statistical method, the Support Vector Machine (SVM) is used to analyse the multi-dimensional data space and to remove source types identified as contaminants (extragalactic sources, main sequence stars, evolved stars and sources related to the interstellar medium). Objects listed in the SIMBAD database are used to identify the already known sources and to train our method. A new all-sky selection of 133,980 Class I/II YSO candidates is presented. The estimated contamination was found to be well below 1% based on comparison with our SIMBAD training set. We also compare our results to that of existing methods and catalogues. The SVM selection process successfully identified >90% of the Class I/II YSOs based on comparison with photometric and spectroscopic YSO catalogues. Our conclusion is that by using the SVM, our classification is able to identify more known YSOs of the training sample than other methods based on colour-colour and magnitude-colour selection. The distribution of the YSO candidates well correlates with that of the Planck Galactic Cold Clumps in the Taurus–Auriga–Perseus–California region.
Peptide hormone exendin‐4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of parkinson's disease

We investigated the effects of exendin‐4 on neural stem/progenitor cells in the subventricular zone of the adult rodent brain and its functional effects in an animal model of Parkinson's disease. Our results showed expression of GLP‐1 receptor mRNA or protein in the subventricular zone and cultured neural stem/progenitor cells isolated from this region. In vitro, exendin‐4 increased the number of neural stem/progenitor cells, and the number of cells expressing the neuronal markers microtubule‐associated protein 2, β‐III‐tubulin, and neuron‐specific enolase. When exendin‐4 was given intraperitoneally to naïve rodents together with bromodeoxyuridine, a marker for DNA synthesis, both the number of bromodeoxyuridine‐positive cells and the number of neuronal precursor cells expressing doublecortin were increased. Exendin‐4 was tested in the 6‐hydroxydopamine model of Parkinson's disease to investigate its possible functional effects in an animal model with neuronal loss. After unilateral lesion and a 5‐week stabilization period, the rats were treated for 3 weeks with exendin‐4. We found a reduction of amphetamine‐induced rotations in animals receiving exendin‐4 that persisted for several weeks after drug administration had been terminated. Histological analysis showed that exendin‐4 significantly increased the number of both tyrosine hydroxylase‐ and vesicular monoamine transporter 2‐positive neurons in the substantia nigra. In conclusion, our results show that exendin‐4 is able to promote adult neurogenesis in vitro and in vivo, normalize dopamine imbalance, and increase the number of cells positive for markers of dopaminergic neurons in the substantia nigra in a model of Parkinson's disease. © 2007 Wiley‐Liss, Inc.
Regulation of cellular and humoral immune responses by T-cell subclasses.

Properties of three major T-cell subclasses are discussed with regard to the following: functional properties; production of helper factors; killer function; immunosuppressive activity; role of T-cell subclasses in the response to modified-self; and regulatory effects of H-2 activated T-cell subclasses upon antibody responses. Other topics discussed are a tentative developmental model for generation of self-reactive Te cells and T-cell diversity, and possible mechanisms of T c/s suppression. (HLW)
Improving T cell therapy for cancer

Adoptive transfer of antigen-specific T cells has been most effective in treating cytomegalovirus (CMV) disease and Epstein–Barr virus (EBV)-associated lymphoproliferative disease (LPD). Both of these diseases develop only during periods of acute immune suppression, and both involve highly immunogenic infected cells, and thus respond well to T cell therapies. In contrast, tumours that develop in the presence of a competent immune system evolve complex immune evasion strategies to avoid and subvert T cell-mediated killing. Therefore, even T cells that display potent cytotoxic activity against tumour cells in vitro may not be effective in vivo without altering the tumour:T cell balance in favour of the T cell. This review discusses several new areas of research aimed at improving adoptive T cell therapy for the treatment of cancer, including the genetic modification of antigen-specific T cells to allow them to perform better in vivo, and conditioning the host to improve in vivo expansion and function of transferred cells.
Conservation theorems for the Cohesiveness Principle

We prove that the Cohesiveness Principle (COH) is Π 1 1 conservative over RCA 0 +IΣ 0 n and over RCA 0 + BΣ 0 n for all n ≥ 2 by recursion-theoretic means. We ﬁrst characterize COH over RCA 0 + BΣ 02 as a ‘jumped’ version of Weak K¨onig’s Lemma (WKL) and develop suitable machinery including a version of the Friedberg jump-inversion theorem. The main theorem is obtained when we combine these with known results about WKL. In an appendix we give a proof of the Π 11 conservativity of WKL over RCA 0 by way of the Superlow Basis Theorem and a new proof of a recent jump-inversion theorem of Towsner.
Targeted recombinant aequorins: Tools for monitoring [Ca2+] in the various compartments of a living cell

In the last decade, the study of Ca2+ homeostasis within organelles in living cells has been greatly enhanced by the utilisation of a recombinant Ca2+‐sensitive photoprotein, aequorin. Aequorin is a Ca2+ sensitive photoprotein of a coelenterate that, in the past, was widely employed to measure Ca2+ concentration in living cells. In fact, the purified protein was widely used to monitor cytoplasmic [Ca2+] changes in invertebrate muscle cells after microinjection. However, due to the time‐consuming and traumatic procedure of microinjection, the role of aequorin in the study of Ca2+ homeostasis remained confined to a limited number of cells (giant cells) susceptible to microinjection. Thus, in most instances, it was replaced by the fluorescent indicators developed by Roger Tsien and coworkers. The cloning of aequorin cDNA [Inouye et al. (1985) Proc. Natl. Acad. Sci. U.S.A. 82:3154–3158] and the explosive development of molecular biology offered new possibilities in the use of aequorin, as microinjection has been replaced by the simpler technique of cDNA transfection. As a polypeptide, aequorin allows the endogenous production of the photoprotein in cell systems as diverse as bacteria, yeast, slime molds, plants, and mammalian cells. Moreover, it is possible to specifically localise it within the cell by including defined targeting signals in the amino acid sequence. Targeted recombinant aequorins represent to date the most specific means of monitoring [Ca2+] in subcellular organelles. In this review, we will not discuss the procedure of aequorin microinjection and its use as purified protein but we will present the new advances provided by recombinant aequorin in the study of intracellular Ca2+ homeostasis, discussing in greater detail the advantages and disadvantages in the use of this probe. Microsc. Res. Tech. 46:380–389, 1999. © 1999 Wiley‐Liss, Inc.
Board Level Cyclic Bending Test for MCP Package

With the increasing requirement of thinner, higher density and multi-function product, MCP (multi-chip product) is becoming a more and more popular package used in many kinds of portable products like mobile phone, PDA, and digital camera, etc. And the miniaturization trend of these electronic products has resulted in the vulnerability of solder joint interconnections which can be reflected in board level cyclic bending test. The test was conducted according to JEDEC standard. Every 100 cycles the resistances was checked and a 10% increase in resistance was considered as a failure. The failure location depends largely on the board PCB pad structure design. It was observed that packages mounted on via in pad PCB have cracks mostly along solder/substrate pad interface area, while packages mounted on no via in pad PCB, most cracks happen at the trace neck area. And it was noticed that for via in pad and no via in pad PCB, the different effects of various DOE factors could have almost opposite influences.
How to predict the outcome of endoscopic mechanical lithotripsy in patients with difficult bile duct stones?

Objective. Endoscopic mechanical lithotripsy is frequently used to overcome the difficulties of removing large bile duct stones endoscopically. The aim of this study was to identify predictors of endoscopic mechanical lithotripsy failure. Material and methods. One hundred and thirty-four patients who underwent mechanical lithotripsy for difficult choledocholithiasis were evaluated retrospectively. Predictive factors of outcome and procedure-related complications were analyzed. The clinical outcomes of subsequent management were also evaluated in cases of unsuccessful endoscopic mechanical lithotripsy. Results. Endoscopic mechanical lithotripsy was successful in 102 patients (76.1%). Stone impaction, size (≥30 mm), and the stone size to bile duct diameter ratio (>1.0) were significant predictors of endoscopic mechanical lithotripsy failure, with estimated odds ratios of 17.83, 4.32 and 5.47, respectively. There was no difference in complication rates between the successful and failed mechanical lithotripsy groups. When mechanical lithotripsy failed, all patients were successfully treated using various modalities, including surgery, without mortality. Conclusions. An impacted stone, stone size (≥30 mm) and stone size to bile duct diameter ratio (>1.0) were predictors of failure of endoscopic mechanical lithotripsy for a difficult bile duct stone. Alternative approaches should be considered in patients with predictors of unsuccessful endoscopic mechanical lithotripsy in order to avoid wasting time and resources.
The 50:50 method for PCR‐based seamless genome editing in yeast

The ability to edit the yeast genome with relative ease has contributed to the organism being a model eukaryote for decades. Most methods for deleting, inserting or altering genomic sequences require transformation with DNA that carries the desired change and a selectable marker. One‐step genome editing methods retain the selectable marker. Seamless genome editing methods require more steps and a marker that can be used for both positive and negative selection, such as URA3. Here we describe the PCR‐based 50:50 method for seamless genome editing, which requires only two primers, one PCR with a URA3 cassette, and a single yeast transformation. Our method is based on pop‐in/pop‐out gene replacement and is amenable to the facile creation of genomic deletions and short insertions or substitutions. We used the 50:50 method to make two conservative loss‐of‐function mutations in MATα1, with results suggesting that the wild‐type gene has a new function outside of that presently known. Copyright © 2013 John Wiley & Sons, Ltd.