Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploring Relationships Between Traditional and New Media Literacies: British Preteen Texters at School

This article focuses on preteen British children's use of text messaging, particularly the abbreviations and characteristic language used within text messages. We look not only at the language style used by the children, but at the ways in which it relates to their traditional literacy skills, as measured through standardized tests and assessments. We have found repeated positive relationships between use of text register language and traditional literacy skills, and we give here a preview of our latest, longitudinal work, which allows those relationships to be studied directionally, enabling us to draw causal conclusions.
Personality-Guided Therapy in Behavioral Medicine

In "Personality-Guided Therapy in Behavioral Medicine", the latest volume in the "Personality-Guided Psychology" series, Robert G. Harper integrates a broad research base on how personality type interacts with and affects the course of common medical conditions, such as cancer, diabetes and cardiovascular disease. He illuminates why and how patients with specific personality attributes interact with their health care providers, make lifestyle choices that affect the course of disease, make use of psychosocial supports, and cope with the demands of illness as well as treatment. Filled with practical guidance and strategies for treatment in a hospital or outpatient setting, this book has the potential to be of great practical utility for clinicians. Researchers, too, should benefit from an understanding of the various personality disorders and their implications for prevention and treatment.
Peripheral Nerve Stimulation for the Treatment of Occipital Neuralgia and Transformed Migraine Using a C1‐2‐3 Subcutaneous Paddle Style Electrode: A Technical Report

In this article we will discuss the treatment of Occipital Neuralgia (ON) and Transformed Migraine (TM) using a paddle style surgical stimulator lead. A paddle style electrode may have advantages to the cylindrical style in reducing migrations from cervical tension or anchor dislodgement. It should be considered in refractory “neuropathic” cervicocranial syndromes such as ON and TM before moving on to more aggressive surgical interventions.
The role of oncogenes in the radiation response of human tumours : in vitro and clinical studies

Activation of certain oncogenes may alter the sensitivity of cells to ionising radiation. We studied the effect of oncogene activation on the radiation sensitivity of cells of a human melanoma cell line. The cell line IGR39D was transfected with the MYC oncogene, the proto-oncogene NRAS, NRAS activated by a point mutation (61-arginine), or a combination of mutated NRAS and MYC. Single-dose experiments showed a decreased survival after transfection with MYC, wild type NRAS or mutated NRAS. Cotransfection with MYC and mutated NRAS decreased survival up to 4 Gy, whereas at higher dose no shift in radiosensitivity was seen. Flow cytometry data indicated that differences in radiosensitivity could be explained at least in part by a difference in the distribution of cells in the phases of the cell cycle. After transfection of cells with either NRAS or MYC, the number of cells in G1 phase decreased with a concomitant increase of cells in the G2/M phase. When the cell line transfected with activated NRAS was manipulated so that the distribution of the cells in the phases of the cell cycle resembled that of the parental line at the time of radiation, the survival of the cells was improved. Similar experiments with the cell line containing MYC did not result in an alteration of the distribution of the cells in the cycle, or the survival after single dose fractions, suggesting the presence of a distinct mechanism for influencing radiation sensitivity. Both NRAS and MYC transfection decrease the radiation sensitivity of human melanoma cells, but the underlying mechanisms seem different. In conclusion, transfection with NRAS or MYC alone increases radiation sensitivity while transfection of cells containing NRAS with MYC restores resistance at higher doses.
Structures and dynamics in a two-dimensional dipolar dust particle system

The effects of electric dipole moment, the number of dipolar particles, and system temperature on the structures and dynamics of a dipolar dust particle system are studied by molecular dynamics simulations. The results show that the larger electric dipole moment is favorable for the formation of a long-chain structure, the larger number of dipolar dust particles promotes the formation of the multi-chain structure, and the higher system temperature can cause higher rotation frequency. The trajectories, mean square displacement (MSD), and the corresponding spectrum functions of the MSDs are also calculated to illustrate the dynamics of the dipolar dust particle system, which is also closely related to the growth of dust particles. Some simulations are qualitatively in agreement with our experiments and can provide a guide for the study on dust growth, especially on the large-sized particles.The effects of electric dipole moment, the number of dipolar particles, and system temperature on the structures and dynamics of a dipolar dust particle system are studied by molecular dynamics simulations. The results show that the larger electric dipole moment is favorable for the formation of a long-chain structure, the larger number of dipolar dust particles promotes the formation of the multi-chain structure, and the higher system temperature can cause higher rotation frequency. The trajectories, mean square displacement (MSD), and the corresponding spectrum functions of the MSDs are also calculated to illustrate the dynamics of the dipolar dust particle system, which is also closely related to the growth of dust particles. Some simulations are qualitatively in agreement with our experiments and can provide a guide for the study on dust growth, especially on the large-sized particles.
Hypertensi dan Faktor-faktor Risikonya di Indonesia

Background: This study describes the hypertension rate in Indonesia in 2007 and its related factors. The data was obtained from RISKESDAS (Riset Kesehatan Dasar/Basic Health Research) 2007 which included questions of individual, social and physical health of respondents aged 15 years and more during the data collection. Methods: Statistical method used was cross tabulation and un-pair t-test. Results: The result showed that totally 36.3% males and 35 8% females suffered from hypertension. High hypertension rates were found at Gorontalo, East Java, Central Java, Bangka Belitung and West Java provinces. Hypertension began at early aged, those aged 15-18 years, 6. 5% boys and 12.8% girls suffered from hypertension. Being head of the family, low education and not working was related to a higher rate for hypertension. Those with no education have the highest hypertension rate, i.e.: 61.4% among females and 49.0% among males. Pregnant women have lower hypertension rate as compared to non-pregnant women. Those who were unemployed had the high estrate for hypertension (42.4%). Hypertension rate among farmers was higher as compare to fisher-men (42.3% vs 21 8%). Those that suffer from heart disease, Diabetes Mellitus and stroke had a significantly higher hypertension rate than those who were not. Those that smoked or chew tobacco in the past one month has a higher hypertension rate than those who were not smoking or tobacco chewing. The majority of the smokers were heavy smokers.
Do the Pelli-Robson and Test Chart 2000 Xpert demonstrate comparable contrast sensitivity results?

Aim: To establish whether the contrast sensitivity threshold obtained with the computerised Test Chart 2000 Xpert is comparable with the printed Pelli-Robson chart. Methods: Healthy volunteers from a student population were recruited. The inclusion criteria included: monocular visual acuity of at least 0.2 logMAR, no history of any ocular abnormalities and amblyopia, no sign of any manifest strabismus and a Frisby stereo-acuity threshold of at least 85 seconds of arc. Visual acuity was assessed at 1 m to allow the contrast sensitivity to be directly comparable. The results were statistically analysed using a two-factor ANOVA and a paired t-test. Results: Twenty participants (7 male, 13 female) were recruited with a mean age of 20.9 ±6.0 years. The average visual acuity tested at 1 m was -0.05 ±0.12 logMAR for the right eye, -0.07 ±0.11 logMAR for the left eye and ±0.11 ± 0.12 logMAR tested binocularly. The average contrast sensitivity using the Pelli-Robson chart was 1.63 ± 0.02 log unit for the right eye, 1.62 ±0.04 log unit for the left eye and 1.70 ±0.05 log unit when tested with both eyes open. The average contrast sensitivity using the computerised Test Chart 2000 Xpert was 1.84 ±0.13 log unit for the right eye, 1.85 ±0.15 log unit for the left eye and 2.02 ±0.20 log unit when tested with both eyes open. A significant difference was found in contrast sensitivity scores between the two tests ( p < 0.001, paired t-tests). The Test Chart 2000 Xpert also consistently gave higher contrast sensitivity scores when compared with the Pelli-Robson. Weak correlations were noted between visual acuity and both contrast sensitivity tests testing right eye, left eye and with both eyes open, with Pearson’s correlation coefficient values ranging between r = 0.40 and r = 0.11. Conclusion: The study was carried out to determine whether the contrast sensitivity threshold values obtained with the computerised Test Chart 2000 Xpert are comparable with those obtained with the Pelli-Robson chart. A significant difference was found between the scores from the two tests and the Test Chart 2000 Xpert consistently generated a higher contrast sensitivity threshold. This study did not assess test–retest variability. It is acknowledged that further studies with a larger sample size and repeat testing on two visits are required to assess repeatability.
The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000

SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recent developments of the database include format and content enhancements, cross-references to additional databases, new documentation files and improvements to TrEMBL, a computer-annotated supplement to SWISS-PROT. TrEMBL consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDSs) in the EMBL Nucleotide Sequence Database, except the CDSs already included in SWISS-PROT. We also describe the Human Proteomics Initiative (HPI), a major project to annotate all known human sequences according to the quality standards of SWISS-PROT. SWISS-PROT is available at: http://www.expasy. ch/sprot/ and http://www.ebi. ac.uk/swissprot/
RefSeq and LocusLink: NCBI gene-centered resources

Thousands of genes have been painstakingly identified and characterized a few genes at a time. Many thousands more are being predicted by large scale cDNA and genomic sequencing projects, with levels of evidence ranging from supporting mRNA sequence and comparative genomics to computing ab initio models. This, coupled with the burgeoning scientific literature, makes it critical to have a comprehensive directory for genes and reference sequences for key genomes. The NCBI provides two resources, LocusLink and RefSeq, to meet these needs. LocusLink organizes information around genes to generate a central hub for accessing gene-specific information for fruit fly, human, mouse, rat and zebrafish. RefSeq provides reference sequence standards for genomes, transcripts and proteins; human, mouse and rat mRNA RefSeqs, and their corresponding proteins, are discussed here. Together, RefSeq and LocusLink provide a non-redundant view of genes and other loci to support research on genes and gene families, variation, gene expression and genome annotation. Additional information about LocusLink and RefSeq is available at http://www.ncbi. nlm.nih. gov/LocusLink/.
Does presentation of smooth pureed meals improve patients consumption in an acute care setting: A pilot study

Aim Malnutrition is a concern across all Australian hospitals and is associated with negative clinical outcomes in up to 60% inpatients, with a further 10% exacerbated by the presence of dysphagia. Providing adequate nutrition for patients requiring a texture-modified diet often results in meals that look and taste less appealing and which are nutritionally diluted. This article aims is to review change in oral intake using food moulding techniques within an acute care institution for patients on Texture C—smooth pureed meals. Methods This was a 2 week pilot study. Patients were provided smooth pureed lunch either as non-moulded or a moulded meal. Main meal wastage was weighed and reasons for waste were documented. If patients met the inclusion criteria, a short satisfaction survey was also administered. Results Analysis using a chi-squared test comparison saw significance in the proportion of patients increasing oral intake from 3/4 meal, when in the moulded form (P = 0.03). Median plate waste was reduced by over 100 g in the treatment group but there was no significant change overall. Limited data for patient satisfaction concluded no significance in meal preference. Conclusions The pilot study suggests that using a moulded smooth puree diet can increase mean oral intake and reduce main meal wastage, but a larger sample size is required to demonstrate statistical significance. However, the pilot study effect size (0.55) is large enough to warrant further research interest in this area and results do suggest relevancy in clinical practice for replication.
ALFRED: an allele frequency database for diverse populations and DNA polymorphisms - an update

ALFRED (the ALelle FREquency Database) is designed to store and disseminate frequencies of alleles at human polymorphic sites for multiple populations, primarily for the population genetics and molecular anthropology communities. Currently ALFRED has information on over 180 polymorphic sites for more than 70 populations. Since our initial release of the database we have focussed on increasing the quantity and quality of data, making reciprocal links between ALFRED and other related databases, and providing useful tools to make the data more comprehensible to the end user. ALFRED is accessible from the Kidd Lab home page (http://info.med.yale. edu/genetics/kkidd/) or from ALFRED directly (http://alfred.med.yale. edu/alfred/index.asp).
Features of 847 Childhood‐Onset Systemic Lupus Erythematosus Patients in Three Age Groups at Diagnosis: A Brazilian Multicenter Study

To evaluate demographic data and clinical and laboratory features at disease diagnosis in 3 different age groups of childhood‐onset systemic lupus erythematosus (SLE): group A, early‐onset (<6 years); group B, school age (≥6 to <12 years); and group C, adolescent (≥12 to <18 years).
TRANSCompel®: a database on composite regulatory elements in eukaryotic genes

Originating from COMPEL, the TRANSCompel database emphasizes the key role of specific interactions between transcription factors binding to their target sites providing specific features of gene regulation in a particular cellular content. Composite regulatory elements contain two closely situated binding sites for distinct transcription factors and represent minimal functional units providing combinatorial transcriptional regulation. Both specific factor--DNA and factor--factor interactions contribute to the function of composite elements (CEs). Information about the structure of known CEs and specific gene regulation achieved through such CEs appears to be extremely useful for promoter prediction, for gene function prediction and for applied gene engineering as well. Each database entry corresponds to an individual CE within a particular gene and contains information about two binding sites, two corresponding transcription factors and experiments confirming cooperative action between transcription factors. The COMPEL database, equipped with the search and browse tools, is available at http://www.gene-regulation.com/pub/databases.html#transcompel. Moreover, we have developed the program CATCH for searching potential CEs in DNA sequences. It is freely available as CompelPatternSearch at http://compel.bionet. nsc.ru/FunSite/CompelPatternSearch.html.
Research on key technology of planning and design for AC/DC hybrid distribution network

With the increasing demand of DC generation and DC load, the development of DC technology, AC and DC distribution network integrating will become an important form of future distribution network. In this paper, the key technology of planning and design for AC/DC hybrid distribution network is proposed, including the selection of AC and DC voltage series, the design of typical grid structure and the comprehensive evaluation method of planning scheme. The research results provide some ideas and directions for the future development of AC/DC hybrid distribution network.With the increasing demand of DC generation and DC load, the development of DC technology, AC and DC distribution network integrating will become an important form of future distribution network. In this paper, the key technology of planning and design for AC/DC hybrid distribution network is proposed, including the selection of AC and DC voltage series, the design of typical grid structure and the comprehensive evaluation method of planning scheme. The research results provide some ideas and directions for the future development of AC/DC hybrid distribution network.
Consumo de trastuzumab en la unidad de mezclas oncológicas del Hospital Nacional Edgardo Rebagliati Martins, enero-diciembre 2009

The consumption of trastuzumab in oncological mixtures Unit (UMO) of the Hospital Nacional Edgardo Rebagliati Martins was studied during 2009 through retrospective descriptive analysis of the worksheets from the UMO and using of Hospital Management System (SGH) and analysis of written and dispensed prescriptions. The results show that the cost accounting of chemotherapy schemes was S/. 72798,21 for each patient, still the most widely consumed trastuzumab more ixabepilone mixture with an average cost for six cycles S/. 68684, 52. The UMO attended 542 prescriptions and 521 preparations with trastuzumab, which generated an expense of S/. 3798426 and refunds amounted to S/. 704442, this generated a savings of 18,55%.
Incidence of Skin Trauma Associated with Participation in Intercollegiate Soccer

Participation in soccer at the intercollegiate level has increased dramatically in the United States over the past 20 years. Past studies have identified the frequency and mechanisms of musculoskeletal injury among various populations. However, data on the incidence and etiology of skin trauma associated with intercollegiate athletic participation is limited in the literature. The purpose of this study was to measure the frequency of skin trauma and determine the injury rate (IR) based on exposure to injury among male and female soccer student-athletes at a NCAA Division II institution. A case reporting and exposure form was used to collect the data over a competitive soccer season. Descriptive statistics were calculated for the data. A total of 18 wounds were documented, 11 (61%) among males and 7 (39%) among females. The overall IR for males was 4.6 wounds/1000 athletic exposures (AE) and females 3.9 wounds /1000 AE. The most common wounds were blisters (83.3%) and abrasions (16.7%) occurring most frequently to midfielders (61%). The most common mechanism of injury was rubbing/friction (94.4%) through contact with clothing (44.4%). The reported wounds occurred during practice (77.8%) and competition (11.1%) activities on grass (94.4%). The most frequently injured body locations were the foot (38.9%) and heel (27.8%). As risk factors are identified, steps toward prevention, management, and cost-effectiveness strategies can be developed.
Aligned Protein–Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue‐Engineering Platform

Sustained release of proteins from aligned polymeric fibers holds great potential in tissue‐engineering applications. These protein–polymer composite fibers possess high surface‐area‐to‐volume ratios for cell attachment, and can provide biochemical and topographic cues to enhance tissue regeneration. Aligned biodegradable polymeric fibers that encapsulate human glial cell‐derived neurotrophic factor (GDNF, 0.13 wt %) were fabricated via electrospinning a copolymer of caprolactone and ethyl ethylene phosphate (PCLEEP) with GDNF. The protein was randomly dispersed throughout the polymer matrix in aggregate form, and released in a sustained manner for up to two months. The efficacy of these composite fibers was tested in a rat model for peripheral nerve‐injury treatment. Rats were divided into four groups, receiving either empty PCLEEP tubes (control); tubes with plain PCLEEP electrospun fibers aligned longitudinally (EF‐L) or circumferentially (EF‐C); or tubes with aligned GDNF‐PCLEEP fibers (EF‐L‐GDNF). After three months, bridging of a 15 mm critical defect gap by the regenerated nerve was observed in all the rats that received nerve conduits with electrospun fibers, as opposed to 50 % in the control group. Electrophysiological recovery was seen in 20 %, 33 %, and 44 % of the rats in the EF‐C, EF‐L, and EF‐L‐GDNF groups respectively, whilst none was observed in the controls. This study has demonstrated that, without further modification, plain electrospun fibers can help in peripheral nerve regeneration; however, the synergistic effect of an encapsulated growth factor facilitated a more significant recovery. This study also demonstrated the novel use of electrospinning to incorporate biochemical and topographical cues into a single implant for in vivo tissue‐engineering applications.
Clinical Picture and Audiometric Configurations in Meniere's Disease

The typical characteristics of patients with Meniere's disease were analysed by gathering data of patients treated for the disease in Finnish hospitals A total of 442 patient charts were retrospectively examined, and 221 definite cases were identified. Various parameters, such as age, gender, sex, marital and occupational status, laterality of the disease and concomitant chronic diseases, including other internal ear disorders affecting hearing capacity, were analysed. The audiometric configurations of the latest audiograms were classified according to an EU Work Group classification and a new mid-frequency based classification, and these classifications were evaluated in relation to the duration of the disease. Sixty-two percent of the patients were female, and the median age of all subjects was 60 years. The disease was bilateral in 13% of the patients, and 26% of the patients were hearing aid users. No single occupation was overrepresented. Ischaemic heart disease seemed to be more common among the patients with Meniere's disease than in the general population. Almost half of the patients were retired, but Meniere's disease had been the cause of retirement for less than half of the retired subjects. Vertigo appeared to be the predominant symptom, and the half of the patients had had a vertiginous episode lasting for more than three hours. Half of the patients had significant functional impairment because of the disease. Thirty-two percent had participated in short-term rehabilitation courses for patients with Meniere's disease. The disease was controlled conservatively in 69% of the cases. A gently sloping high-frequency pattern was most prevalent according to the EU Work Group classification and a flat pattern according to the mid-frequency based classification. In both classifications, the ascending configuration was most typically seen in patients who had had the disease for 2 to 10 years.