Miracle-dz/UniFAR-FTUs huggingface dataset:
Gaining insight in factors associated with successful ageing: body composition, nutrition, and cognition

Frailty is defined as a geriatric condition characterized by an increased vulnerability to external stressors, leading to a loss of reserve capacity. This condition is characterized by a loss of muscle mass. Muscle ultrasound might play an important role in quantifying this loss, and therefore the validity and reliability of muscle ultrasound was investigated. Furthermore, this thesis aimed to identify methods for determining malnutrition and lastly we investigated the influence of nutrition and exercise on psychosocial frailty. This thesis shows that muscle ultrasound is a valid and reliable method for determining muscle size. Currently, muscle ultrasound cannot be used to diagnose sarcopenia and malnutrition because in both definitions it is not muscle size, but (whole body) muscle mass that is determined. Determining muscle size is important as it provides possibilities for starting targeted interventions. For example, in the event of loss of muscle mass in the lower limbs, exercise intervention may be indicated as part of the treatment. Another recommendation from this thesis is that normative data for muscle size should be determined, in order to be included in the criteria of sarcopenia and malnutrition. This dissertation also suggests that a healthy diet plays an important role in cognitive functioning and that protein intake contributes to the maintenance of muscle mass.
Prevention of kidney injury after myocardial ischemia reperfusion is achievable with short-term protein restriction

Introduction: Kidney injury is a serious complication after cardiovascular surgery. Left ventricular dysfunction, pre-operative kidney dysfunction and inflammation can predict kidney injury after myocardial reperfusion. Objectives: We aimed to study whether short-term protein restriction (PR) would influence blood urea nitrogen (BUN) levels after myocardial reperfusion injury. Materials and Methods: Male Wistar rats fed with either AIN-93M or AIN-93M protein restricted diet one week before myocardial reperfusion injury. After surgery, feeding continued with AIN-93M for 1 week. Results: BUN levels increased significantly compared to the pre-operative level in the control group (P=0.03) and decreased significantly in the protein-restricted group (P=0.01). Multivariate analysis showed that PR through its effect on blood glucose (β=1.2, 95% CI=0.1- 2.34), IL-6 (β=-2.22, 95% CI=-3.9–-0.54) and left ventricular ejection fraction (LVEF) (β=-1.21, 95% CI=-2.34- 0.09) was able to protect the kidney from myocardial reperfusion. Conclusion: Short-term PR through modulating pre-operative IL-6, post-operative blood glucose levels and LVEF could prevent kidney injury after myocardial reperfusion injury.
Observation of Human Behaviour in Reference to Human-like Motions of Animated Avatars

There exist many different opinions and miscellaneous researches regarding to Moris theory about the “Uncanny Valley” meaning the effect, when human likeness and eeriness stand in a non-linear relationship for the appearance of robots and virtual faces. Some of them depict that motion do not affect the valley in any way, but they implied it wrongly for interactions. In this thesis we wanted to investigate in the change of behaviour, when humans interact with virtual 3D avatars. Therefore we recorded various animation of a real human and mapped them onto virtual faces. Then we designed an experiment with 18 participants, who were shown four different inanimated computer generated faces and afterwards the same faces animated for an interaction, in a random order. The interaction was made with a game called “WHO AM I? ”, where they slip into the role of a well known character and than had to figure out through “yes” or “no” questions who they are. After each inanimated face as well as after each interaction they had to fulfil a questionnaire, to rate human likeness, eeriness and attractiveness of the virtual avatars. We evaluated significant positive effects of human likeness and attractiveness due to interactions with computer generated avatars.
Evaluation of a Pharmacy Continuing Education Program: Long-Term Learning Out-comes and Changes in Practice Behaviors

Objectives. To assess the long-term outcomes from a 3-month, curriculum-based pharmacy continuing education (CPE) program on lipid management and hypertension services, particularly changes in practice behaviors. Methods. An interactive lipid management and hypertension services pharmacy continuing education program focusing on the development of cognitive and psychomotor skills was developed and offered. A pre- and post-program survey was developed to assess participant knowledge related to 12 cognitive and psychomotor concepts derived from program objectives. Participants were asked about their practice settings and percentage of time engaged in practice-related activities, and whether the program influenced subsequent practice behaviors, specifically the provision of clinical services. Results. Forty-six of 49 participants completed the preprogram survey with 65% and 37% post-program response rates at 6 and 12 months, respectively. Significant improvements in participant knowledge base and skills were .
Effect of puerarin on the expression of NF-κB65 and TNF-α in kidney of diabetic rats

Objective To observe the effect of puerarin on the expression of NF-κB65 and TNF-α in kidney of diabetic rats. Methods SD rats were randomly assigned to 5 groups (10 each):normal control group (group A),diabetic group (group B),low-dose,middle-dose and high-dose treatment groups (group C,D and E). After diabetes model was reproduced,animals in group C,D and E were i.p. injected with puerarin in a dose of 40,80 and 160mg/(kg·d),respectively; animals in group A and B were treated with corresponding normal saline. Fasting blood glucose (FBG),urinary albumin excretory rate (UAER),serum creatinine (Scr) and blood urea nitrogen (BUN) were determined at the 8th weekend after treatment. The histological changes in renal cortex were observed with light microscope and electron microscope. The qualitative and semi-quantitative expressions of NF-κB65 and TNF-α in nephridial tissue were determined by immunohistochemical method. Results FBG,UAER,Scr and BUN were higher in group C,D and E than that in group A (P0.01 or P0.05),but much lower than those in group B (P0.01 or P0.05). Renal pathologic changes in diabetic rats in puerarin treatment groups were improved. Expressions of NF-κB65 and TNF-α were lower in group C,D and E than that in group B. Conclusions Puerarin can reduce urinary albumin excretion,improve glucose metabolism,renal function and pathology of diabetic rat. The protective effects of puerarin on diabetic rat kidney may be related to the down-regulation of NF-κB65 and TNF-α expression in renal tissue.
OH level populations and accuracies of Einstein-A coefficients from hundreds of measured lines

Abstract. OH airglow is an important nocturnal emission of the Earth's mesopause region. As it is chemiluminescent radiation in a thin medium, the population distribution over the various roto-vibrational OH energy levels of the electronic ground state is not in local thermodynamic equilibrium (LTE). In order to better understand these non-LTE effects, we studied hundreds of OH lines in a high-quality mean spectrum based on observations with the high-resolution Ultraviolet and Visual Echelle Spectrograph at Cerro Paranal in Chile. Our derived populations cover vibrational levels between v=3 and 9, rotational levels up to N=24, and individual Λ-doublet components when resolved. As the reliability of these results critically depends on the Einstein-A coefficients used, we tested six different sets and found clear systematic errors in all of them, especially for Q-branch lines and individual Λ-doublet components. In order to minimise the deviations in the populations for the same upper level, we used the most promising coefficients from Brooke et al. (2016) and further improved them with an empirical correction approach. The resulting rotational level populations show a clear bimodality for each v, which is characterised by a probably fully thermalised cold component and a hot population where the rotational temperature increases between v=9 and 4 from about 700 to about 7000 K, and the corresponding contribution to the total population at the lowest N decreases by an order of magnitude. The presence of the hot populations causes non-LTE contributions to rotational temperatures at low N, which can be estimated quite robustly based on the two-temperature model. The bimodality is also clearly indicated by the dependence of the populations on changes in the effective emission height of the OH emission layer. The degree of thermalisation decreases with increasing layer height due to a higher fraction of the hot component. Our high-quality population data are promising with respect to a better understanding of the OH thermalisation process.
Ameliorative potential of Anacyclus pyrethrum extract in generalized seizures in rat: Possible cholinergic mediated mechanism

The present study evaluates the anticonvulsant activity of the roots of Anacyclus pyrethrum using pilocarpine-induced experimental model of epilepsy in rat, and to determine its possible anticonvulsant mechanism. Ethanol extract (200 and 400 mg/kg) or alkylamides (25 and 50 mg/kg) was administered orally 45 min before the injection of pilocarpine-induced (400 mg/kg) seizures. The possible anticonvulsant mechanism was investigated by testing the effect of atropine (2 mL/kg) and scopolamine (1 mg/kg). The scoring of seizure severity, seizures time latency, duration of total seizures and percentage of mortality protection were recorded. Ethanol extract and alkylamides prolonged the time of onset seizure and decreased the duration of seizures compared to control group (p<0.001). The seizure protection was 100%. The co-administered of ethanol extract of A. pyrethrum and alkylamides with atropine completely abolished the pilocarpine-induced seizures. Video Clip of Methodology: Anticonvulsant effect: 6 min 7 sec: Full Screen Alternate
1 Preparation of cationized starch from food industry waste biomass and its utilization in sulfate 1 removal from aqueous solution 2 3

Preparation of cationized starch from food industry waste biomass and its utilization in sulfate 1 removal from aqueous solution 2 3 Katja Lappalainen*, Johanna Kärkkäinen, Matti Niemelä, Harri Vartiainen, Olli Rissanen and 4 Hanne Korva 5 Sustainable Chemistry Research Unit, University of Oulu, P.O. Box 4300, FIN-90014 University of 6 Oulu, Finland; 7 Katja.Lappalainen@oulu.fi; Johanna.Karkkainen@oulu.fi; Matti.Niemela@oulu.fi; 8 Harri.Vartiainen53@gmail.com; Juho.Rissanen@student.oulu.fi; Hanne.Korva@gmail.com 9 *Corresponding author: Tel. +358-50-5398060, E-mail address: Katja.Lappalainen@oulu.fi 10 11
Investigation of the relationship between the spatial gradient of total electron content (TEC) between two nearby stations and the occurrence of ionospheric irregularities

Abstract. The relation between the occurrence of ionospheric irregularities and the spatial gradient of total electron content (TEC) derived from two closely located stations (ASAB: 4.34 ∘ N, 114.39 ∘ E and DEBK: 3.71 ∘ N, 109.34 ∘ E, geomagnetic), located within the equatorial region, over Ethiopia, during the postsunset hours was investigated. In this study, the Global Positioning System (GPS)-derived TEC during the year 2014 obtained from the two stations were employed to investigate the relationship between the gradient of TEC and occurrence of ionospheric irregularities. The spatial gradient of TEC ( ΔTEC∕Δlong ) and its standard deviation over 15 min, σ(ΔTEC∕Δlong ), were used in this study. The rate of change of TEC-derived indices (ROTI, ROTI ave ) were also utilized. Our results revealed that most of the maximum enhancement and reduction values in ΔTEC∕Δlong are noticeable during the time period between 19:00 and 24:00 LT. In some cases, the peak values in the spatial gradient of TEC are also observed during daytime and postmidnight hours. The intensity level of σ(ΔTEC∕Δlong) observed after postsunset show similar trends with ROTI ave , and was stronger (weaker) during equinoctial (solstice) months. The observed enhancement of σ(ΔTEC∕Δlong) in the equinoctial season shows an equinoctial asymmetry where the March equinox was greater than the September equinox. During the postsunset period, the relation between the spatial gradient of TEC obtained from two closely located Global Navigation Satellite System (GNSS) receivers and the equatorial electric field (EEF) was observed. The variation in the gradient of TEC and ROTI ave observed during the evening time period show similar trends with EEF with a delay of about 1–2 h between them. The relationship between σ(ΔTEC∕Δlong) and ROTI ave correlate linearly with correlation coefficient of C=0.7975 and C=0.7915 over ASAB and DEBK, respectively. The majority of the maximum enhancement and reduction in the spatial gradient of TEC observed during the evening time period may be associated with ionospheric irregularities or equatorial plasma bubbles. In addition to latitudinal gradients, the longitudinal gradient of TEC has contributed significantly to the TEC fluctuations.
Dealing with temporariness

Purpose A major trend in the changing nature of work is the increasing use of temporary workers. Although common among students, older employees have joined the ranks of temporary workers as they extend their work lives. Temporary workers tend to report lower affective commitment and consequently poorer work outcomes. However, different generations of workers may conceive temporary work differently from each other. The purpose of this paper is to explore how different generations of temporary workers, respond to human resource practices (HRP), which in turn influences their affective commitment and work performance. Design/methodology/approach The sample is comprised of 3,876 temporary agency workers (TAWs) from seven temporary employment agencies in Portugal. The authors undertook multiple group SEM analyses to test a moderated mediation model that accounts for TAWs’ affective commitment (toward the agency and the client company) across three generations (Baby Boomers, Generation X and Millennials) in the relationship between human resources practices and overall perceived performance. Findings After controlling for gender, age and tenure, the authors find generational differences in the perceptions of HRP and perceived performance. The results support the moderator effect of generations in the direct and indirect relationships – through both affective commitments – between TAWs’ perceived HRP and perceived performance. Research limitations/implications The cross-sectional design limits the possibility to make causal inferences. Originality/value This study contributes to a better understanding of how different generations respond to temporary employment relationships. The findings suggest important differences in the way in which the same HRP system relates (directly and indirectly thorough affective commitment toward the client) with their perceived performance across different generations.
Top management teams’ demographics effect on earnings management - A Swedish perspective

We study whether the demographic characteristics of top management teams influence earnings management, by using a sample of Swedish listed firms from 2010-2014. Our findings suggest that the demographic characteristics (i.e. age, gender, education, financial work experience, international experience and tenure) of top management teams influence their earnings management activities. We find significance for both accruals-based and real activitybased earnings management, however, the results for accruals-based are notably weaker than for real activity-based earnings management. The upper echelons theory predictions are moderately consistent with our results. The results can nonetheless be used by people responsible for compiling and developing chief level executive teams, and additionally, by auditing firms when assessing the risk of top management conducting earnings management.
Factors Influencing Generation Y Satisfaction in Sundanese Restaurant

The purpose of this study is to determine and analyze the factors that affect customer satisfaction among generation Y at Traditional Sundanese restaurant in Bandung. Three restaurants were selected as the objects of this study. All the three are the most widely recommended through the internet. The generation Y was chosen as the subject of the research because the generation Y is a generation that is dominating the market nowadays. The dimensions of restaurant attributes in this study consist of food quality, service quality, and atmosphere. The type of research was descriptive verification and the technique of sampling used was a survey by using cluster random sampling technique. The number of respondents is 400 consumers who made purchases at those three Sundanese restaurants in Bandung. The Data analysis technique used was multiple regression analysis. The result found that restaurant attributes gave significant influence on customer satisfaction of generation Y. The most influential factor is service quality. Keywords—restaurant attributes; customer satisfaction;
COPD_A_220861 2993..3002

1Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan; 2Department of Internal Medicine, Fukuwa Clinic, Tokyo, Japan; 3Clinical Research Center, National Hospital Organization, Kinki-Chuo Chest Medical Center, Osaka, Japan; 4Respiratory Center, Matsusaka Municipal Hospital, Matsusaka, Japan; 5Pulmonary Research Institute of Southeast Michigan, Farmington Hills, MI, USA; 6LungenClinic Grosshansdorf and Christian-Albrechts University Kiel, Airway Research Center North, Member of the German Center for Lung Research (DZL), Großhansdorf, Germany; 7AstraZeneca K.K. , Osaka, Japan; 8AstraZeneca, Durham, NC, USA; 9AstraZeneca, Morristown, NJ, USA; 10Formerly of AstraZeneca, Durham, NC, USA; 11AstraZeneca, Gothenburg, Sweden Background: Budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler (BGF MDI) is a triple fixed-dose combination for COPD. The long-term safety of triple therapy for COPD has not been investigated in Japanese patients. In this 28-week extension study (NCT03262012), we investigated the long-term safety and tolerability of BGF MDI in Japanese patients with moderate-to-very severe COPD who completed the 24-week Phase III randomized, double-blind, multicenter KRONOS study (NCT02497001). Materials and methods: Patients randomized to BGF MDI 320/18/9.6 μg, glycopyrrolate/ formoterol fumarate (GFF) MDI 18/9.6 μg, budesonide/formoterol fumarate (BFF) MDI 320/ 9.6 μg, or budesonide/formoterol fumarate dry powder inhaler (BUD/FORM DPI) 400/12 μg twice-daily in KRONOS continued treatment for up to 28 additional weeks. Safety was evaluated over 52 weeks via adverse event (AE) monitoring, electrocardiograms, clinical laboratory testing, and vital sign measurements. Results: The safety population included 416 patients who received BGF MDI (n=139), GFF MDI (n=138), BFF MDI (n=70), or BUD/FORM DPI (n=69). Treatment-emergent AE (TEAE) rates were similar across treatment groups (range: 82.6–82.9%). The most frequent TEAEs overall were nasopharyngitis (32.2%) and bronchitis (9.9%). The incidence of major adverse cardiovascular events was low across groups (range: 0.0–2.9%). Over 52 weeks, the incidence of confirmed pneumonia was 9.4% (BGF MDI), 3.6% (GFF MDI), 5.7% (BFF MDI), and 2.9% (BUD/FORM DPI); in the 28-week extension period, rates were comparable across groups (range: 2.9–5.7%). Six deaths were reported (0.7–2.2% per group); none were considered treatment-related. No clinically meaningful trends were observed in electrocardiograms, laboratory parameters, or vital signs over time in any of the treatment groups. Conclusion: All treatments were well tolerated over 52 weeks, and the safety profile of BGF MDI was generally comparable to dual long-acting muscarinic antagonist (LAMA)/ long-acting β2-agonist (LABA) and inhaled corticosteroid (ICS)/LABA therapies. These findings support the long-term tolerability of BGF MDI in Japanese patients with COPD.
Environmental Characteristics: Moderator of Strategic Planning Process Formality and Performance

Strategic planning processes do not seem to have significant influence on the performance of institutions due to some perceived level of negligence in acknowledging the contribution of environmental factors. The process appears to have become routine exercise without due consideration to elements within its environments (O‟Regan & Ghobadian, 2007, in Boateng et al., 2015). Many plans are shelved and do not influence output as a result of this (Bracker& Pearson, 1986). Business environments seem to have been changing – and so should institutional approaches. The study has therefore examined environmental characteristics of institutions, and the volume of their moderated influence on the relationship between their strategic planning processes and performance. It provides institutions with broader understanding of their environments, and how to smoothly adapt internal resources for enhanced performance. It informs decision makers, the strategies to pursue for enhanced performance, based on characteristics within their environments. The hypotheses tested at 0.05 level of significance was that environmental characteristics have no significant moderating influence on the strategic planning process formality-performance relationship. This hypothesis is influenced by the dynamic capabilities theory, and contingency theory. The ability to identify and analyze environmental factors could lead to better strategic choices for improved performance. The environments are considered key contingency variables for relationships between strategy and performance.
On Structural Data Extraction in Surgical Cases

Nowadays surgical cases are recorded in the form of text. These texts contain a lot of useful information for future analysis and data mining. Through the analysis of the structured information such as time, region and typical symptoms of diseases extracted from a large number of surgical texts, a hospital can grasp the overall trend of a certain kind of disease and gather much useful information for illness diagnosis. Furthermore, for a certain patient it is also necessary to analyze and understand the historical surgical records of the patient when determining the current surgical plan for him. Especial for lung and thoracic surgery, it is of great 网络出版时间:2019-10-16 13:42:08 网络出版地址:http://kns.cnki. net/kcms/detail/11.1826. TP.20191016. 1043.006. html