Miracle-dz/UniFAR-FTUs huggingface dataset:
The role of the locus coeruleus in the generation of pathological anxiety

This review aims to synthesise a large pre-clinical and clinical literature related to a hypothesised role of the locus coeruleus norepinephrine system in responses to acute and chronic threat, as well as the emergence of pathological anxiety. The locus coeruleus has widespread norepinephrine projections throughout the central nervous system, which act to globally modulate arousal states and adaptive behavior, crucially positioned to play a significant role in modulating both ascending visceral and descending cortical neurocognitive information. In response to threat or a stressor, the locus coeruleus–norepinephrine system globally modulates arousal, alerting and orienting functions and can have a powerful effect on the regulation of multiple memory systems. Chronic stress leads to amplification of locus coeruleus reactivity to subsequent stressors, which is coupled with the emergence of pathological anxiety-like behaviors in rodents. While direct in vivo evidence for locus coeruleus dysfunction in humans with pathological anxiety remains limited, recent advances in high-resolution 7-T magnetic resonance imaging and computational modeling approaches are starting to provide new insights into locus coeruleus characteristics.
Natural control of a lower-limb exoskeleton: using upper-body kinematics to detect gait initiation intention

Over the last few decades, medical lower-limb exoskeletons have emerged from various research teams and private industrials to serve as assistive or rehabilitation devices [1]. While still facing many challenges regarding their development and design, these robotic structures show promising results for being used in real-world settings, and allow either safe ambulation of people suffering from lower-limb impairments [2]. One key aspect in the development of lower-limb exoskeletons is their ability to be perceived as integrated parts of the users’ bodies [3]. However, in order to achieve such an integration, it is important to provide correct interfacing with the users’ sensory-motor control system and to properly convey movement intentions through natural and intuitive control strategies. Most marketed devices rely on constraining interfaces based on external inputs or the execution of predefined movements to trigger different walking states [4], [5]. But knowledge on human motor control and the analysis of specific body motions can be exploited to build more intuitive and robust interfaces. In particular, the natural kinematic coordination between different parts of the body during gait events can exhibit predictive patterns, such as the anticipatory postural adjustments (APAs) that appear during gait initiation [6]. With the use of machine learning and pattern recognition techniques, it is possible to properly identify such patterns in unimpaired individuals in a free walking setting based on inertial measurements [7]. In recently published work, we showed that similar patterns still exist when unimpaired individuals have their legs constrained by a lower-limb exoskeleton, and can be successfully used within a supervised classification architecture to trigger the robot’s walking state with minimal false positive rates [8].
Schwilch, Gudrun and Bernet, Lea and Fleskens, Luuk and Giannakis, Elias and Leventon,

Despite numerous research efforts over the last decades, integrating the concept of ecosystem services into land management decision-making continues to pose considerable challenges. Researchers have developed many different frameworks to operationalize the concept, but these are often specific to a certain issue and each have their own definitions and understandings of particular terms. Based on a comprehensive review of the current scientific debate, the EU FP7 project RECARE proposes an adapted framework for soil-related ecosystem services that is suited for practical application in the prevention and remediation of soil degradation across Europe. We have adapted existing frameworks by integrating components from soil science while attempting to introduce a consistent terminology that is understandable to a variety of stakeholders. RECARE aims to assess how soil threats and prevention and remediation measures affect ecosystem services. Changes in the natural capital’s properties influence soil
Mass, Nitrogen, and Phosphorus Dynamics in Foliage and Root Detritus of Tallgrass Prairie

Mass nitrogen, and phosphorus of litterfall were measured for 4 yr on annually burned and unburned tallgrass prairie near Manhattan, Kansas. Decomposition and minearilization rates of foliage, flowering stem, and roots were concurrently studied with a series of litterbag and tethered litter experiments. Amounts of nitrogen and phosphorus in living and dead foilage and roots were measured for 2—yr on an annually burned site. Litterfall exhibited seasonal peaks on all sites, with most of the annual litter decompsition occurring in autumn. An average of 52 g°m—2°yr—1 of litter was deposited on the soil of the annually burned watersheds, while 142 g°m—2°—1 was collected on unburned sites. Nitrogen and phosphorus amounts were 0.53 and 0.07 g°m—2°yr—1, respectively, from burned sites and 1.94 and 0.19 g°m—2°yr—1, on unburned sites. Litterfall on unburned sites averaged °35% of aboveground maximum biomass estimates. Litter decay rates varied from a minimum of °10% yr for flowering stems in the canopy to a maximum of °50%/ yr for roots. Foilage and stems act as nitrogen and phosphorus sinks during the first 2 yr of decomposition. Dead roots and rhizomes also act as temporary nitrogen sinks, but unlike foilage, roots appear to minearlize significant amounts of phosphorus during the 1st yr of decay. Root nitrogen to phosphorus ratios may provide a proximate explanation for nitrogen limitation in tallgrass prairies.
Ventral midline thalamus is not necessary for systemic consolidation of a social memory in the rat

According to the standard theory of memory consolidation, recent memories are stored in the hippocampus before their transfer to cortical modules, a process called systemic consolidation. The ventral midline thalamus (reuniens and rhomboid nuclei, ReRh) takes part in this transfer as its lesion disrupts systemic consolidation of spatial and contextual fear memories. Here, we wondered whether ReRh lesions would also affect the systemic consolidation of another type of memory, namely an olfaction-based social memory. To address this question we focused on social transmission of food preference. Adult Long-Evans rats were subjected to N-methyl-d-aspartate-induced, fibre-sparing lesions of the ReRh nuclei or to a sham-operation, and subsequently trained in a social transmission of food preference paradigm. Retrieval was tested on the next day (recent memory, nSham = 10, nReRh = 12) or after a 25-day delay (remote memory, nSham = 10, nReRh = 10). All rats, whether sham-operated or subjected to ReRh lesions, learned and remembered the task normally, whatever the delay. Compared to our former results on spatial and contextual fear memories (Ali et al., 2017; Klein et al., 2019; Loureiro et al., 2012; Quet et al., 2020), the present findings indicate that the ReRh nuclei might not be part of a generic, systemic consolidation mechanism processing all kinds of memories in order to make them persistent. The difference between social transmission of food preference and spatial or contextual fear memories could be explained by the fact that social transmission of food preference is not hippocampus-dependent and that the persistence of social transmission of food preference memory relies on different circuits.
Assessing the Impact of Parents’ Adolescent Reproductive and Sexual Health Knowledge on Sexual Health Education by Parents in the Asutifi (North and South) Districts of Ghana

Parent‟s involvement in adolescent sexual health education has been identified as one of the effective ways of reducing sexual risk behaviour among adolescents. However, a number of factors may prevent parents from carrying out adolescent sexual health education. Four hundred and twenty-four (424) parents/guardians, including 180 males and 244 females were randomly selected from the Asutifi north and south districts of the BrongAhafo region of Ghana for the crosssectional study. Self-administered and interviewer-administered questionnaires consisting of demographic characteristics, parent‟s knowledge on adolescent sexual health, socioeconomic factors, cultural factors and practice of sexual health education were the measures for the study. Literate respondents had self-administered questionnaire while illiterate respondents had interviewer administered questionnaires. Interviewers translated the questionnaire from the English language to the local language (Twi) for illiterate respondents to ensure better understanding of the questions. 86.1% of the surveyed parents practice adolescent sexual health education. Females as well as married parents were found to practice sexual health education (SHE) more than male and unmarried parents respectively. Two variables remained significant after controlling for relevant demographic and other factors. These included parent‟s knowledges on adolescent sexual health (OR=2.35; 95% CI 1.34-4.09) and parents‟ level of education (OR= 3.47; 95% CI 1.27-9.45). Government agencies in collaboration with stake holders should develop policies that will ensure that parents are given the necessary training that will boost both their level of education and knowledge on adolescent sexual health.
KNOWLEDGE MODELING FOR HERITAGE CONSERVATION PROCESS: FROM SURVEY TO HBIM IMPLEMENTATION

Abstract. This paper aims to develop a strategy for architectural knowledge modeling in order to actively support the built heritage conservation process by fostering collaboration among stakeholders and interoperability between datasets. The integration of two modeling systems, one ontology-based and one in BIM environment, seems to be the right way to meet this objective: the former is rather exhaustive to represent the semantic contents of conservation activities, especially non-geometrical data, the latter is absolutely suitable to represent the logic of the construction, above all geometrical-constructive aspects typical of any architectural organism. Thus, this study proposes a side-by-side approach to synchronize these different ways of representing reality by managing the complexity of cultural heritage on the one hand and of technology tools, such as information systems, on the other. The proposed methodology was tested on the city walls of San Ginesio (Macerata, Italy) and included different steps considering the in-use technologies (notably geomatics and information technologies) as key enablers to acquire, hierarchically order, model and enrich the knowledge of that heritage site. The result is a knowledge-led strategy moving from survey to HBIM implementation, as a way to enhance representation and management in architectural heritage processes.
CONTEMPORARY CONCEPTS OF THE PHILLIPS CURVE AND MACROECONOMIC STABILIZATION POLICY

The stabilization of economic activity represents the basic purpose of macroeconomic policy. In the last few years, the achievement of price stability, or the relatively low and stable inflation rate, has been imposed as the policy’s main goal, in accordance with the recommendations of the so-called New consensus macroeconomics. In line with that, the identification of variables, which determine the inflation rate and cause its changes, is crucial. From its occurrence, the relationship of the Phillips curve provided an explanation of the inflation dynamics based on the movement of different factors, depending on the variant of the curve observed. Hence, the subject of the paper is the presentation and evaluation of the contemporary concepts of the Phillips curve in the context of the application of the efficient stabilization policy. The main objective of the paper is to reconsider the concept’s validity, especially in the conditions of serious economic disorders, such as the Great Recession. The applied analysis indicates that the dominant New Keynesian concept of the Phillips curve can serve for the successful conducting of economic policy, if it is supplemented with the variables of fiscal policy and financial stability policy.
A study on fruit preparation on quality of fig fruits (cv. Bellary) osmotic-dehydrated under solar tunnel dryer

Dehydration of fruit and vegetables is one of the oldest techniques known to man and consists primarily of sun drying or artificial dehydration of fruits and vegetables. Fig fruits are climacteric, highly perishable, and higher in respiration rate and ethylene production. Fresh figs cannot be stored for longer period at ambient condition but the dried figs can be stored for 6–8 months. The fig varieties grown locally on a large scale (Bellary fig in Karnataka) are not yielding acceptable colour and taste in dried fig. This is partly due to natural low TSS (9 ̊Brix) in these figs as compared to exotic fig varieties. Therefore, this study was conducted to improve quality of dehydrated fig by imposing pre-drying treatments to whole fig fruit, pricked whole fig fruit, or fruits cut as halves and quarters. The common pre-treatment was blanching (4 minutes) + 0.2% KMS (Potassium metabisulfite) + steeping in 40B sugar solution containing 0.25% citric acid for 24 hours. The pre-treated fruits were dried by employing solar tunnel dryer and analysed for physico-chemical and sensory attributes. The fruits cut to quarter shape showed maximum dried fruit recovery (23.52%) with minimum time taken for dehydration (83.70hours). The same treatment recorded higher L*(40.15), lower a*(9.06) and b*(19.05) value with acceptable organoleptic properties.
The predictive value of serum myeloma protein in solitary plasmacytoma

Purpose To identify the clinical usefulness of serum M protein and to establish a rationale for regular follow-up with serum protein electrophoresis in solitary plasmacytoma. Materials and Methods Sixty-nine patients with solitary plasmacytoma and solitary plasmacytoma with minimal marrow involvement according to the International Myeloma Working Group criteria were retrospectively reviewed. Results At a median follow-up of 6.2 years, 5-year local control (LC), 5-year multiple myeloma-free survival (MMFS), 5-year failure-free survival (FFS), and 5-year overall survival (OS) were 82.6%, 44.1%, 41.8%, and 85.1%, respectively. Among the patients whose initial serum M protein was present or not evaluated, 37.3% of patients showed disappearance of serum M protein after various treatment. MMFS of these patients were comparable to non-secretory plasmacytoma with undetectable levels of M protein, and significantly better than patients with persistent M protein. Increase of serum M protein ≥0.1 g/dL was most predictive of treatment failure with area under the curve of 0.731. Conclusion Patients who eventually showed persistence of serum M protein after treatment showed worse MMFS and FFS compared to those whose serum M protein disappeared or who had initially non-secretory disease. The increase of serum M protein level ≥0.1 g/dL from current nadir was predictive of treatment failure. Therefore, regular follow-up with serum M protein is highly recommended especially unless the patient had initially non-secretory disease.
LinnOS: Predictability on Unpredictable Flash Storage with a Light Neural Network

This paper presents LinnOS, an operating system that leverages a light neural network for inferring SSD performance at a very ﬁne—per-IO—granularity and helps parallel storage applications achieve performance predictability. Lin-nOS supports black-box devices and real production traces without requiring any extra input from users, while outper-forming industrial mechanisms and other approaches. Our evaluation shows that, compared to hedging and heuristic-based methods, LinnOS improves the average I/O latencies by 11.9-66.4% with 87-97% inference accuracy and 4-6 µ s inference overhead for each I/O, demonstrating how to incorporate machine learning inside operating systems for real-time decision-making.
ECharacterize: A Novel Feature Selection-Based Framework for Characterizing Entrepreneurial Influencers in Arabic Twitter

Abstract— Social media are widely used as communication platforms in the world of business. Twitter, in particular, offers valuable opportunities for collaboration due to its open nature. For that, many entrepreneurs employ Twitter for different reasons, such as mobilizing financial resources, get funding, and increase their innovation capabilities. Therefore, they keep looking for local entrepreneurial accounts to help them. Messages from entrepreneurial influencers -opinion leader- increase the information diffusion to entrepreneurs, helping them to find more opportunities. Discovering the characteristics of entrepreneurial influencers in Twitter networks becomes extremely important since it reflects the way to reach entrepreneurs. In the present paper, we propose a novel framework called ECharacterize based on feature selections techniques to discover the characteristics of the entrepreneurial influencer in the Saudi context in a robust manner. The framework extracts abundant influencers’ features and then employs seven state-of-the-art ranking methods to determine the characteristics of the most relevant influencer. It robustly aggregates the lists to come out with the accurate final list using Robust Rank Aggregation. The framework examined on 233,018 real-life Arabic tweets. The results show the ability of the proposed method to distinguish between the influencers by their popularity, reliability and activity level.
Draft 1 Molecular diversity and species delimitation in the family Gasteruptiidae 2 ( Hymenoptera : Evanioidea ) 3 4

Journal: Genome Manuscript ID gen-2019-0186.R1 Manuscript Type: Article Date Submitted by the Author: 20-Apr-2020 Complete List of Authors: Parslow, Ben; Flinders University of South Australia, College of Science and Engineering; South Australian Museum, Schwarz, Michael; Flinders University Stevens, Mark; South Australia Museum Keyword: ABGD, GMYC, Hymenoptera, COI, DNA barcode Is the invited manuscript for consideration in a Special Issue? : Trends in DNA Barcoding and Metabarcoding 2019
Selection of a legume to use in a low phosphorus loss pasture

ABSTRACT Phosphorus loss from pastures can impair surface water quality. Losses can be partly minimised by maintaining a low soil Olsen P concentration, but there is still potential to reduce these further by minimising P lost from plant shoot material. Furthermore, although ryegrass can produce well at low Olsen P, many legumes cannot. We tested and categorised the potential for P losses (as water extractable P) from shoot material for 10 species (ryegrass, legumes and herbs) and the supporting Pallic soil over a range of Olsen P concentrations. White clover was categorised as having low potential for P loss from shoot material while exhibiting high yield relative to other species. This was especially the case at an Olsen P concentration of 15 mg kg−1—targeted as the minimum Olsen P required for good ryegrass yield, but requiring little P inputs, and likely to lose little P to surface water. However, other legumes may be more suitable under different soil or climatic conditions.
Evaluation of Drug Related Problems in Patients with Chronic Disease at Tertiary Care Teaching Hospital

Drug related problem is a broad term because it includes problems related to the drug at any level of use that is the prescribing level, dispensing level, administration level or at the patient or care taker level. In this study the case reports were analyzed using patient profile, patient medication chart, medication history interview and other information’s were also analyzed. Out of the identified patients 54.1 % were male and 45.8% were female, the presence of DRPs is calculated according to the age, and it was found that patient present with an age of ≥60 years are more prone to have DRPs. 21% of this population was suffering from ADRs, and 37.91% ware with no optimal treatment. 16% of patient present with unnecessary treatment. Prescriber level intervention was more that only proposed. According to the study around 32% of the intervention proposed were implemented, almost 36% of total population were present with partially solved DRPs. Since the medicine can cure illness and at the same time can harm the patient if not appropriately used. Clinical pharmacist can play a key role in promoting better medication use, ensuring that patients receive appropriate pharmacotherapy thus helps in minimizing the risk of unfavorable outcomes of pharmacotherapy.
MOLECULAR CHARACTERIZATION OF ANTIBIOTIC RESISTANCE IN GRAM – NEGATIVE BACTERIA ISOLATED FROM DAIRY PRODUCTS

The present work was carried out on 127 dairy products samples (62 buffalo milk, 46 cow milk, 16 kariesh cheeses and 3 yoghurt) were obtained from retail markets in Dakahlia governorate. (214) isolates were assayed for antimicrobial susceptibility, the presence of integrons and antimicrobial resistance genes. 152 out of 214 (71.02%) Gram – negative bacterial isolates showed multidrug resistance phenotypes for two or more of the following antimicrobial agents: ampicillin, streptomycin, gentamicin, tetracycline, trimethoprim/ sulfamethoxazole, nalidixic acid, ciprofloxacin, amoxicillin clavulanic acid , chloramphenicol and cefotaxime . PCR screening for integrons showed that eight (3.73%) isolates of (Enterobacter aerogens, Klebsiella pneumoniae, Klebsiella oxytoca, Citrobacter diversus, Citrobacter freundii, Proteus vulgaris, Escherichia coli and Serratia marsescens) were positive for class 1 integron and all isolates were negative for class 2 integron . βlactamase resistance gene blaTEM was identified in 6 (2.80%) isolates of (K. oxytoca , E. coli , S. liquefaciens ,E. cloacae, K. pneumoniae and C. diversus). blaCTX-M was identified in 3 (1.40%) isolates of (E. coli , K. oxytoca, and S. marsescens). All isolates were negative for blaCMY. Molecular Characterization Of Antibiotic Resistance In . Amany , M. I. et. , al. Kafr El-Sheikh Vet.Med.J. Vol. 1 No.1 (2003) 04 These results highlighted the role of antimicrobial use in dairy animals and development of transferable gene in bacteria in dairy animals from which such genes can be disseminated by horizontal gene transfer to other bacteria and reach human pathogens.
Group of Isometries of Niederreiter-Rosenbloom-Tsfasman Block Space

Let P = ({1, 2, ., n}, ≤) be a poset that is an union of disjoint chains of the same length and V = F^N_q be the space of N-tuples over the ﬁnite ﬁeld Fq. Let Vi = F^{k_i}_q , with 1 ≤ i ≤ n, be a family of ﬁnite-dimensional linear spaces such that k_1 + k_2 + . + k_n = N and let V = V_1×V_2×. ×V_n endow with the poset block metric d_(P,π) induced by the poset P and the partition π = (k_1, k_2, ., k_n), encompassing both Niederreiter-Rosenbloom-Tsfasman metric and error-block metric. In this paper, we give a complete description of group of isometries of the metric space (V, d_(P,π)), also called the Niederreiter-Rosenbloom-Tsfasman block space. In particular, we reobtain the group of isometries of the Niederreiter-Rosenbloom-Tsfasman space and obtain the group of isometries of the error-block metric space.