Miracle-dz/UniFAR-FTUs huggingface dataset:
Plasma osmolality in acute spontanious intra-cerebral hemorrhage: Does it influence hematoma volume and clinical outcome?

Background: Neurological deterioration in acute spontaneous intra cerebral hemorrhage (ICH) may depend on hematoma volume, electrolyte imbalances, hydration status and other physiological parameters. Plasma osmolality is a marker of hydration. This study has examined the relationship of plasma osmolality with hematoma volume and clinical outcome. Materials and Methods: This is a prospective observational study included 75 patients with non-traumatic acute spontaneous ICH. Plasma osmolality, hematoma volume and clinical outcome in National Institute Health stroke scale (NIHSS) were measured on admission and on day 7 after treatment. Mean plasma osmolality was compared between those who died before day 7 and those who died after day 7. Plasma osmolality was also compared between patients with NIHSS score >20 and patients with NIHSS score ≤20. Paired t test, Pearson correlation coefficient and independent sample t test were done using SPSS software (version 17 for Windows). Result: There is no significant correlation between hematoma volume and plasma osmolality. Higher admission plasma osmolality was associated with early death [312.0 (±16.0) mOsm/kg for those who died before day 7 versus 297.0 (±14.7) mOsm/kg for those who died after day 7, P value =0.031]. Higher admission plasma osmolality was associated with very severe stroke [311.5 (±14.1) mOsm/Kg for patients with NIHSS score >20 versus 293.6 (±11.3) mOsm/kg for patients with NIHSS score ≤20, P value =0.000). Conclusion: High plasma osmolality is a predictor of early mortality. Hematoma volume is not influenced by plasma osmolality.
Solution of the vectorial 3D inverse source problem by adjoint near-field fast multipole translations

A fast imaging algorithm based on adjoint near-field fast multipole translations and hierarchical multilevel disaggregations is presented to solve the full vectorial 3D inverse source problem. The problem formulation is related to the plane wave based near-field far-field transformation, where the inverse problem is solved iteratively. Our algorithm, however, only requires a single processing step. The described algorithm produces very good results in numerical tests with observation data of full spherical coverage.
Decomposition Algorithms for Single-Machine Sequencing with Precedence Relations and Deferral Costs

A one-machine deterministic job-shop sequencing problem is considered. Associated with each job is its processing time and linear deferral cost. In addition, the jobs are related by a general precedence relation. The objective is to order the jobs so as to minimize the sum of the deferral costs, subject to the constraint that the ordering must be consistent with the precedence relation. A decomposition algorithm is presented, and it is proved that a permutation is optimal if and only if it can be generated by this algorithm. Four special network structures are then considered, and specializations of the general algorithm are presented.
How Domain Knowledge Accumulation Influences Software Defects: An Empirical Analysis

Understanding the trend of software defect density at the time of delivery has significant implications for organizations or agencies to make long-term risk control strategies. Software development is a knowledge-intensive activity. Organizations and software developers are expected to reduce defects rates with the accumulation of knowledge and experience, however, they are constantly confronted with challenges imposed by new projects. This paper investigates the compound effects of knowledge experience and new projects on software defects. The study performs an empirical analysis on 60 software systems developed by 8 organizations in the Chinese aviation industry from year 2007 to 2014. The results show that the density of severe defects obviously reduces over time, but no consistent trend is observed for defects of low severity. Moreover, the density of high severity defects acutely increases in newly developed projects. This reveals that enhanced strategies should be employed to reduce severe defects in new software projects, in addition to the current practices of software process improvement.
No Room of Their Own: Gender and Nation in Israeli Women's Fiction

IntroductionI. "Running with She-Wolves"? II. The "New Hebrew Woman"III. The Subject of PostmodernismIV. Isreal and the European "Woman Question"One: Emerging SubjectsI. The Masked Autobiography: Genre and GenderII. What Does a Woman Want? Shulamit Lapid and the Feminist RomanceTwo: Alterity Revisited: Gender Theory and Israeli Literary FeminismI. Beauvior's Drama of SubjectivityII. Beauvoir's "Daughters": Otherness as DifferenceIII. Postmodernism's "Other": Mother's Body, Mother's TongueIV. Empowering the M/Other? Three: Empowering the Other: Amalia Kahana-CarmonI. Feminine, Feminist, or Modernist? II. A Brotherhood of Outsiders: Women/Jews/Blacks in Up in MontiferIII. The Brotherhood That Cannot HoldFour: Who's Afraid of Androgyny? Virginia Woolf's "Gender" avant la lettreI. Untangling the Homoerotic Web: Between Orlando and A Room of One's OwnII. Who's Afraid of Father and Mother(hood)? Back To The LighthouseIII. Jewish Mothers and Israeli AndrogynyFive: Israeli Androgyny Under Siege: Shulamith HarevenI. Gendered Selves in City of Many Days: Same, Different, or Repressed? II. Androgynous "Jewish Parents"? Not in a War Zone! III. Trauma and Homoeroticism: Loneliness, an Israeli StorySix: The Leaning Ivory Tower: Feminist PoliticsI. Oedipal Tyrannies: Woolf's Psychopolitics in Three GuineasII. The Leaning Israeli Tower: Feminism ReinventedIII. Monotheistic Tyrannies: Israeli PsychopoliticsSeven: 1948-Hebrew "Gender" and Zionist Ideology: Netiva Ben YehudaEight: Beyond The Feminist Romance: Ruth AlmogI. From The Madwoman in the Attic to The Women's RoomII. The Sins of Their Father(s) or, A Portrait of the Artist as a Young GirlIII. Love and Work? Embracing the M/Other in Roots of AirIV. From Hysteria to HerStory: Artistic MendingAfterword: The Nineties-Prelude to a Postmodernist Millennium?
Total plasma clearance of 51Cr-EDTA: Variation with age and sex in normal adults

Although inulin clearance measured during constant infusion is still considered the reference method, single-injection of 51Cr-EDTA with subsequent plasma sampling has become the most popular technique for the routine assessment of glomerular filtration rate. Despite the fact that the technique has been in use for 30 years, there are only a few reports of normal values calculated directly from 51Cr-EDTA data and normal ranges have generally been produced by conversions of inulin data. The aim of this study was to measure the variation in total plasma clearance, calculated directly from 51Cr-EDTA measurements, in normal males and females, of Saudi Arabian origin, over a wide range. Altogether, 201 potential kidney donors aged 16-60 years were studied. No statistically significant association of total plasma clearance with age or sex could be demonstrated; however, predictive equations suggesting a small decline in total plasma clearance with age were developed. The figures presented suggest that the reduction in total plasma clearance of 51Cr-EDTA with age is relatively shallow up to the age of at least 60 years and that normal ranges produced by conversion of inulin data may overestimate the decline with age.
Les institutions françaises de la sûreté nucléaire: un point de vue historique et ethnographique

Rendue possible par les decouvertes scientifiques majeures du vingtieme siecle, l'exploitation de la matiere fissile a edifie un marche mondial de l'energie nucleaire. Tres vite, le souci de restreindre les applications de cette energie au domaine civil et la necessite d'en maitriser les consequences quant a la sante des populations ont encourage la communaute internationale, a reglementer et controler l'acces a ce marche. C'est ainsi qu'est creee en 1957 l'agence internationale de l'energie atomique (AIEA), dont un des roles est d'etablir les standards de la surete nucleaire au niveau mondial. Cinquante plus tard, par le biais de cette agence et de bien d'autres organismes internationaux (OCDE, WANO) ou regionaux (WENRA, ENSREG,.), l'industrie nucleaire apparait comme un secteur au sein duquel la cooperation internationale est particulierement intense. Neanmoins, les decisions importantes relatives a la surete des installations nucleaires d'un pays sont prises au niveau national. Les recentes controverses europeennes relatives au perimetre, aux objectifs et aux consequences des tests de resistance ( stress-test ) l'illustrent remarquablement : malgre le slogan " an accident somewhere is an accident everywhere ", la surete nucleaire demeure un objet de souverainete nationale. Des lors, pour le citoyen desireux de comprendre le fonctionnement de la surete nucleaire en France, il importe de mieux connaitre les institutions nationales qui l'evaluent, l'expertisent, la controlent, et de qualifier la relation qu'entretiennent ces institutions avec les exploitants du secteur. C'est dans ce but que nous proposons une breve histoire de ces institutions et que nous presentons certains des resultats d'une recherche empirique menee au centre de gestion scientifique de Mines ParisTech, en collaboration avec l'IRSN. Ce travail nous permet de caracteriser le mode de regulation des risques nucleaires en France, qui repose sur le maintien d'un dialogue technique et continu entre experts, autorite et exploitants, dont on soulignera en conclusion les avantages et les inconvenients.
MRED: An Algorithm to Insure High QoS in IP Networks

Abstract—Today’s computer networks support only best-effort service, yet future packet networks will have to support realtime communication services that allow clients to transport information with performance guarantees expressed in terms of delay, delay jitter throughput, and loss rate. Random Early Detection (RED) algorithm is one of the scheduling mechanisms used in IP network. RED is an active queue management scheme that randomly drops packets whenever congestion occurs that results in dropping traffic flow packets that are sensitive to loss. This results in QoS degradation. However, Quality of Service (QoS) is a major factor for a successful business in modern and future network services. In this article, the RED algorithm is modified in order to minimize the packet loss of sensitive traffic flows. Evaluation of the proposed enhancement of the RED algorithm is tested using the Network Simulator (NS-2). Then these results are compared with the current RED algorithm. The proposed model shows ten improvements in QoS of sensitive traffic flows.
Resize My Image: A mobile app for interactive image resizing using multi operator and interactive genetic algorithm

In this research a new android app for smartphones to smartly resize images is presented. The smart image resize method was based on a dynamic programming approach that used image edge tangent flow as the energy function to be minimized, known as flow-guided seam carving method. However, a simple but useful interface is needed in a mobile app. Therefore, we developed an interactive approach to image resizing by applying an interactive genetic algorithm. After installing the developed app on the smartphone, we asked test participants to rate the results of this approach. The usability testing results showed that the average score of this approach is higher than that using a single operator.
Loss of Transgelin in Breast and Colon Tumors and in RIE-1 Cells by Ras Deregulation of Gene Expression through Raf-independent Pathways*

Activated Ras but not Raf can transform RIE-1 and other epithelial cells, indicating the critical importance of Raf-independent effector function in Ras transformation of epithelial cells. To elucidate the nature of these Raf-independent activities, we utilized representational difference analysis to identify genes aberrantly expressed by Ras through Raf-independent mechanisms in RIE-1 cells. We identified a total of 22 genes, both known and novel, whose expression was either activated (10) or abolished (12) by Ras but not Raf. The genes up-regulated encode proteins involved in protein or DNA synthesis, regulation of protease activity, or ligand binding, whereas those genes down-regulated encode actin cytoskeletal-, extracellular matrix-, and gap junction-associated proteins, and transmembrane receptor- or cytokine-like proteins. These results suggest that a key function of Raf-independent signaling involves deregulation of gene expression. We further characterized transgelin as a gene whose expression was abolished by Ras. Transgelin was identified previously as a protein whose expression was lost in virally transformed cell lines. We show that this loss is regulated at the level of gene expression and that both Raf-dependent and Raf-independent pathways are required to cause Ras down-regulation of transgelin in RIE-1 cells, whereas Raf alone is sufficient to cause its loss in NIH 3T3 fibroblasts. We also found that Ras-dependent and Ras-independent mechanisms can cause the down-regulation of transgelin in human breast and colon carcinoma cells lines and patient-derived tumor samples. We conclude that loss of transgelin gene expression may be an important early event in tumor progression and a diagnostic marker for breast and colon cancer development.
Sustained postexercise vasodilatation and histamine receptor activation following small muscle‐mass exercise in humans

• What is the central question of this study? The role of histamine‐mediated vasodilatation has been studied in the context of whole‐body cycling but not small muscle‐mass exercise. • What is the main finding and its importance? These data indicate that histamine receptors are activated following dynamic, but not resistance, exercise. Furthermore, these data suggest that local factors associated with aerobic exercise, and not systemic factors, are responsible for activation of histamine receptors in the previously exercised muscle.
Phosphorus release during decomposition of Tubifex residues from wastewater treatment system

Release of phosphorus(P) into effluent of activated sludge process was reported in the recent researches of sludge reduction induced by Tubifex. Decomposition of Tubifex residues is considered to be accompanied by the release of P. A series of experiments were undertaken to evaluate the influence of phosphorus which released from the Tubifex residues to the wastewater treatment system. In present study, it indicated that the release rate of PO<inf>3−</inf><sup>4</sup>-P and total phosphorus (TP) were 3.8×10<sup>−4</sup> mgPO<inf>3−</inf><sup>4</sup>-P / gWorm (dry weight) h and 4.2×10<sup>−4</sup> mgTP /gWorm (dry weight) h, respectively. Compared to the phosphorus release rate of worm's predation on activated sludge, the phosphorus release rate of decomposition of Tubifex residues was slow. Therefore, the influence of P from Tubifex residues decomposition to wastewater treatment system might can be ignored.
Distal myopathy with cachexia: an unrecognised phenotype caused by dominantly-inherited mitochondrial polymerase γ mutations

Background The myopathy associated with mutations in the nuclear-encoded mitochondrial DNA maintenance gene POLG, coding for the catalytic subunit of DNA polymerase, is typically proximal with early ophthalmoplegia. Results We report two unrelated patients in whom a distal, mainly upper limb, myopathy was the predominant and early clinical feature. One patient also suffered with marked cachexia. DNA genomic sequence analysis identified novel dominant heterozygous missense POLG mutations (Leu896Arg and Tyr951His) located within the conserved catalytic polymerase domain of the protein in both cases. Conclusions Distal upper limb myopathy/cachexia is not previously described with dominant POLG mutations and our observations further highlight the diverse clinical spectrum of POLG-related mitochondrial disorders. These data indicate that dominant POLG mutations should be considered in the differential diagnosis of distal upper limb predominant myopathy.
High Intrinsic Sensitivity Etched Polymer Fiber Bragg Grating Pair for Simultaneous Strain and Temperature Measurements

A sensing configuration for simultaneous measurement of strain and temperature with enhanced intrinsic sensitivity based on a fiber Bragg grating (FBG) pair with one grating inscribed in the etched and the other in unetched polymer fiber region is demonstrated. A poly (methyl methacrylate) based single-mode polymer fiber is etched to different diameters, and it is observed that etching can lead to change in the material properties of the fiber, such as Young's modulus and thermal expansion coefficient, which can play a vital role in improving its intrinsic sensing capabilities. Thus, exploiting the different strain and temperature sensitivities exhibited by etched and unetched polymer FBGs, strain and temperature can be simultaneously measured with very high sensitivity. Experimental results show that rms deviations of ±8.42 με and ±0.39 °C for strain and temperature, respectively, in a real simultaneous measurement. The effect of individual thermal and strain sensitivity coefficients on measurement accuracy is also analyzed.
Reformulación de consensos pos-NICE-SUGAR en el manejo de hiperglicemia intrahospitalaria para el médico internista.

La presente revision esta sustentada en la necesidad de poner en practica la evidencia clinica actualizada en el manejo de la hiperglicemia intrahospitalaria (HIH), particularmente luego de los estudios multicentricos y metaanalisis de mayor validez interna publicados durante el 2008-2010 sobre el tema y que obligan a reformular los objetivos glicemicos de protocolos y guias. Este problema clinico es muy frecuente en la practica diaria del medico internista, ya que estos pacientes representan hasta el 30% de las altas del servicio de medicina Interna y aproximadamente el 22% de todos los dias-cama hospital son ocupados por diabeticos. Ademas, un tercio de todos los casos de HIH no han tenido historia previa de diabetes, lo que explica que los casos de HIH superen ampliamente a los de diabetes mellitus descompensada en las salas de emergencia, medicina interna, cirugia y UCI. Se someten a consideracion algunas pautas de manejo de HIH segun las guias de hospitales universitarios y sociedades academicas del primer mundo, con base en los consensos actuales sobre control glicemico estrecho pero no demasiado exigente, ya que la hipoglicemia nosocomial tambien es un factor de riesgo independiente de mortalidad que deberia evitarse.
Consideration of a Thin Flap as an Entity and Clinical Applications of the Thin Anterolateral Thigh Flap

&NA; A defatted (thinned) anterolateral thigh flap was designed to reconstruct skin defects requiring thin flap coverage. We used this flap as a free flap for five cases of skin defects, and the outcomes of the reconstructions were all successful. The vascular pedicle of this flap, the cutaneous perforator of the lateral circumflex femoral artery, is about 8 cm long and 2 mm in diameter, and it is ideal for microvascular anastomosis. Thinning is performed in about 3 to 4 mm of thickness almost uniformly except for the vascular pedicle. It was ascertained as one of the useful donor sites of the free thin flap. The virtue of the thin anterolateral thigh flap is its uniform thinness compared with other thin flaps reported previously—the thin groin flap and the thin rectus abdominis musculocutaneous flap. We considered thin flaps as an entity, and they are classified into three types. (Plast. Reconstr. Surg. 97: 985, 1996.)
Fibromyalgia and Enthesitis in Psoriatic Arthritis. Time to “Characterize” and “Refine” Clinical Definitions

Psoriatic arthritis (PsA) is a complex disease characterized by the presence of polyarthritis, spinal disease, dactylitis, enthesitis, and cutaneous involvement1. Due to considerable research efforts in PsA in recent years, criteria for classification of PsA2 (the CASPAR criteria) have been developed, as well as definitions of clinical features and how to assess them3. In terms of evaluating disease activity, efforts are being made to determine whether composite measures of disease activity and response to therapy can be developed to cover all the domains that characterize PsA4. At present a patient can be classified as having PsA by meeting the CASPAR criteria; nevertheless, in applying the criteria, it is mandatory that the patient must have an inflammatory articular disease (joint, spine, or entheseal). The lack of definition of these entry criteria, crucial for applying the CASPAR criteria, may explain some of the difficulties in clinical research in PsA; for instance, validation of the CASPAR criteria for diagnostic purposes encounters difficulty when criteria are used in a general setting5. Two recent studies5,6 testing the sensitivity of the CASPAR criteria in early PsA found different results (99.1% vs … Address correspondence to Dr. Fernandez-Sueiro, Rheumatology Division, Complejo Hospitalario Universitario, C/. Xubias, 84, 15006, La Coruna, Galicia, Spain. E-mail: L.sueiro{at}canalejo.org
Gestational diabetes exhibits lack of carnitine deficiency despite relatively low carnitine levels and alterations in ketogenesis

Objective: Previous studies have underlined the importance of the carnitine shuttle system and its dysfunction both in normal pregnancy and in type 1 and 2 diabetes. The objective of this paper was to delineate more systematically the role of the carnitine shuttle system in normal pregnancy and in gestational diabetes. Methods: A total of 119 women matched for age comprised three groups: 40 normal adult non-pregnant women (NNP), 46 normal pregnant women with uncomplicated pregnancy (NP) and 33 women with gestational diabetes (GDM). The latter group was further subdivided into those being managed either by diet alone (25 women, GDM-D) or by insulin (8 women, GDM-I). The following biochemical parameters were assayed: fasting plasma total, free and acyl-carnitine, FFA and β-OH-butyrate, together with several essential anthropometric parameters. Results: Women with GDM, in contrast to the control groups, displayed the biochemical features characteristic of insulin resistance: higher body weight, higher BMI, higher skinfold and higher HbA1c levels. No differences on any parameters were found between the two GDM subgroups. Both NP and GDM groups had low levels of total carnitine compared to NNP control group, but surprisingly, the GDM group did not exhibit any further decrease of carnitine levels, as would have been expected by the combination of pregnancy and diabetes. Both groups, despite these low carnitine levels, had no clinical symptoms of carnitine deficiency. Furthermore, the GDM group displayed higher levels of FFA and β-hydroxybutyrate, which were statistically significant compared to the other two control groups. Conclusions: The data corroborate the negative effect of normal gestation on the carnitine shuttle system, while they document for the first time that GDM does not further affect the efficiency of the carnitine system. The mild effect of GDM on carnitine status could be explained by the concurrent increased gluconeogenesis, a process which does not affect directly carnitine metabolism.
Preliminary report on a simple new assay for DNA-protein cross-links as a biomarker of exposures experienced by welders.

A method originally developed to detect topoisomerase DNA complexes has been adapted to determine DNA-protein cross-links formed in cells following their exposure in vitro and in vivo to cross-linking agents. A preliminary study on welders and controls has been carried out to assess the feasibility of this assay to detect human exposure to chromium (Cr) and nickel (Ni) that are associated with increased DNA-protein cross-links. The percentage of cross-link was significantly higher among welders (1.85% +/- 1.14) than among controls (1.17% +/- 0.46; p = .01) Cross-links were not affected by age, weight, or smoking status. The assay developed has substantial advantages over previous methods, being considerably more simple, inexpensive, and sensitive.