Drug Induced T-wave Abnormalities : Beyond QTc Dissertation for the Degree of Doctor of Philosophy

1. Graff C, Toft E, Matz J, Kanters JK, Andersen MP, Nielsen J, Struijk JJ. Covariate analysis of Twave morphology and QTc prolongation: New insights into drug-induced ECG changes. WorldPharma, Copenhagen, Denmark (2010) 2. Graff C, Toft E, Matz J, Kanters JK, Andersen MP, Nielsen J, Struijk JJ. Covariate assessment of T-wave morphology and QTc prolongation: New opportunities in the evaluation of drug-induced ECG changes. Danish Cardiovascular Research Academy, Sønderborg, Denmark (2010) 3. Graff C, Matz, J, Andersen MP, Kanters JK, Nielsen J, Xue JQ, Toft E, Struijk JJ. Druginduced ECG Changes: Beyond the QT Interval. Danish Society for Biomedical Engineering, Brædstrup, Denmark (2009) 4. Schmidt S, Toft E, Holst-Hansen C, Graff C, Struijk J. Segmentation of heart sound recordings by a duration dependent hidden Markov model. Danish Cardiovascular Research Academy, Sønderborg, Denmark (2009) 5. Haarmark C, Hansen PR, Vedel-Larsen E, HaahrPederrsen S, Graff C, Andersen MP, Toft E, Struijk JJ, Kanterrs JK. Alterations in Tpeak-Tend Interval, ST Segment Deviation and QTc in Patients with ST Segment Elevation Myocardial Infarction Immediately After Primary PCI. European Cardiac Arrhythmia Society, Paris, France (2009) 6. Graff C, Matz J, Andersen MP, Kanters JK, Toft E, Pehrson S, Struijk JJ. Drug-induced Effects on T-wave Morphology and QTc. Danish Society of Pharmacology and Toxicology, Odense, Denmark (2008) 7. Nielsen J, Graff C, Hardahl TB, Andersen MP, Kristoffersen J, Struijk JJ, Toft E. ECG Changes During Sertindole Treatment. European College of Neuropsychopharmacology, Barcelona, Spain (2008) 8. Struijk JJ, Andersen MP, Graff C, Kanters JK, Xue JQ, Toft E. Inferior and Lateral Leads Show Similar Tpeak-Tend Intervals in Sotalol-induced QT Prolongation. International Society for Computerized Electrocardiology, Riverside, CA, USA (2008) 9. Fanø S, Haarmark C, Jensen GB, Andersen MP, Graff C, Struijk JJ, Toft E, Christiansen M, Kanters JK. Methadone Induced hERG-blockage Compared to Congenital hERG Mutations (LQT2) Illustrated by T-wave Morphology Changes. European Cardiac Arrhythmia Society, Marseille, France (2008) 10. Graff C, Matz J, Andersen MP, Kanters JK, Toft E, Pehrson S, Struijk JJ. Sensitivity of QTc and Twave Morphology to Small Drug-induced Electrocardiographic Changes. International Drug-induced T-wave Abnormalities: Beyond QTc 25 Society for Computerized Electrocardiology, Riverside, CA, USA (2008) 11. Matz J, Graff C, Andersen MP, Kanters JK, Toft E, Pehrson S, Struijk JJ. Sensitivity of T-wave Morphology and the QT Interval to Small Druginduced ECG Changes. DIA Cardiac Safety Conference, Barcelona, Spain (2008) 12. Haarmark C, Andersen MP, Graff C, Hardahl TB, Struijk JJ, Toft E, Hansen PR, Kanterrs JK. T-wave Amplitude in Lead V1 is Bimodally Distributed. European Cardiac Arrhythmia Society, Marseille, France (2008) 13. Graff C, Matz J, Andersen MP, Kanters JK, Toft E, Pehrson S, Struijk JJ. T-wave Morphology is More Sensitive to Drug-induced Changes than the QT Interval. Danish Cardiovascular Research Academy, Sønderborg, Denmark (2008) 14. Haarmark C, Andersen MP, Graff C, Hardahl TB, Struijk JJ, Toft E, Christiansen M, Jensen HK, Kanters JK. T-wave Morphology Differences Depending on Genotype in Long QT Syndrome. European Cardiac Arrhythmia Society, Marseille, France (2008) 15. Graff C, Andersen MP, Xue JQ, Hardahl TB, Kanters JK, Toft E, Christiansen M, Jensen HK, Struijk JJ. T-wave Morphology Reveals Greater Effect of d,l-sotalol than QTc. International Society for Computerized Electrocardiology, Riverside, CA, USA (2008) 16. Haarmark C, Graff C, Andersen MP, Hardahl TB, Struijk JJ, Toft E, Xue JQ, Rowlandson GI, Kanters JK. Independent Novel T-wave Descriptors of Repolarization. International Society for Computerized Electrocardiology, Cancun, Mexico (2007) 17. Haarmark C, Graff C, Andersen MP, Hardahl TB, Struijk JJ, Toft E, Xue JQ, RowlandsonGI, Kanterrs JK. Quantifying the T-wave as a Repolarization Marker. European Cardiac Arrhythmia Society, Marseille, France (2007) 18. Andersen MP, Xue JQ, Graff C, Hardahl TB, Christiansen M, Toft E, Kanters JK, Struijk JJ. Repeatability of T-wave Morphology Measurements: Superiority of a Principal Component Analysis-based Lead. International Society for Computerized Electrocardiology, Cancun, Mexico (2007) 19. Graff C, Xue JQ, Andersen MP, Kanters JK, Hardahl TB, Toft E, Christiansen M, Struijk JJ. Twave Convexity Measure Outperforms Notch Criterion as Diagnostic Marker for the hERG Genotype. International Society for Computerized Electrocardiology, Cancun, Mexico (2007) 20. Andersen MP, Xue JQ, Graff C, Hardahl TB, Christiansen M, Toft E, Kanters JK, Struijk JJ. Twave Morphology Analysis Identifies Congenital and Drug-induced Long QT Syndrome. Danish Cardiovascular Research Academy, Sønderborg, Denmark (2007) 21. Haarmark C, Graff C, Andersen MP, Hardahl TB, Struijk JJ, Toft E, Christiansen M, Kanterrs JK. T-wave Morphology in the Long QT Syndrome. American Heart Association, Orlando, FL, USA (2007)