Miracle-dz/UniFAR-FTUs huggingface dataset:
Growth Regulators in the Technology of Reproduction of Improved Potatoes

The article is devoted to studying a new generation of plant growth regulators with multi-functional action that are able to simultaneously stimulate growth and development, and to increase adaptability to adverse environmental factors, as well as to influence in the future the resistance of potatoes to diseases, showing strong anti-fungi and antibacterial activity, and ensuring protection from viruses and viroids. In course of the experiment, we studied the effect of growth stimulants (HB-101, Agat-25K and Gumi20) on productivity and quality of potatoes micro plants of the early maturity varieties of domestic (the Udacha variety) and foreign (the Red Scarlet variety) selection obtained by the method of apical meristem in vitro and cultivated in greenhouses. The first spraying with these growth promoters was performed in the budding phase, the next two with an interval of 7 days. The obtained results allow assuming perspective the use of the NV-101 and Agat-25K growth stimulants. A more substantial increase in growth and productivity, as compared to the reference group, was observed after processing domestic Udacha variety with the NV-101 stimulator, and increased resistance to late blight was ensured by a growth regulator with bio-fungicide activity Agat-25K. According to the results of enzyme immunoanalysis (EIA), the viral and bacterial infection is absent in plants in all studied variants. Thus, using growth regulators in the initial stages of the original seed is a promising method, the use of which is necessary due to the varietal characteristics.
E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition

E7080 is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors. In this study, we show the inhibitory activity of E7080 against SCF‐induced angiogenesis in vitro and tumor growth of SCF‐producing human small cell lung carcinoma H146 cells in vivo. E7080 inhibits SCF‐driven tube formation of HUVEC, which express SCF receptor, KIT at the IC50 value of 5.2 nM and it was almost identical for VEGF‐driven one (IC50 = 5.1 nM). To assess the role of SCF/KIT signaling in tumor angiogenesis, we evaluated the effect of imatinib, a selective KIT kinase inhibitor, on tumor growth of H146 cells in nude mice. Imatinib did not show the potent antitumor activity in vitro (IC50 = 2,200 nM), because H146 cells did not express KIT. However, oral administration of imatinib at 160 mg/kg clearly slowed tumor growth of H146 cells in nude mice, accompanied by decreased microvessel density. Oral administration of E7080 inhibited tumor growth of H146 cells at doses of 30 and 100 mg/kg in a dose‐dependent manner and caused tumor regression at 100 mg/kg. While anti‐VEGF antibody also slowed tumor growth, it did not cause tumor regression. These results indicate that KIT signaling has a role in tumor angiogenesis of SCF‐producing H146 cells, and E7080 causes regression of H146 tumors as a result of antiangiogenic activity mediated by inhibition of both KIT and VEGF receptor signaling. E7080 may provide therapeutic benefits in the treatment of SCF‐producing tumors. © 2007 Wiley‐Liss, Inc.
Lymphatics of blood vessels.

In recent years a number of investigations of the anatomy of the vasa vasorum of major blood vessels have been made (1, 2, 3, 4), but few observations of the lymphatic component of vasa vasorum have been recorded. Investigations of lymphatics of blood vessel walls were reported nearly one hundred years ago (5), and the anatomical findings apparently were unclear which resulted in considerable debate among contemporary investigators regarding what had been observed. Most of the controversy seemed to center about whether intercellular spaces were being interpreted as lymphatic capillaries. Some investigators at that time even denied that lymphatics existed within or about the walls of the blood vessels. In recent years there have been only a few reports specifically on the subject (6, 7, 8, 9, 10). The present study describes results of a preliminary investigation to determine the anatomical relationships of lymphatics to the walls of blood vessels. No effort was made to delineate specific lymph drainage pathways.
Beurteilung von Tierschutzleistungen in der Nutztierhaltung

Schon seit vielen Jahren wird eine Debatte um den Tierschutz in der Nutztierhaltung gefuhrt, ohne dass dies nachweislich zu relevanten Verbesserungen fur die Nutztiere gefuhrt hatte. Neben einem konsistenten Beurteilungskonzept mangelt es vielen Betrieben an den diversen dafur erforderlichen Ressourcen und einer effizienten Allokation derselben, um Nutztiere vor klinischen und subklinischen Gesundheitsstorungen zu schutzen sowie an einem adaquaten Umgang mit Zielkonflikten zwischen Nutzungs- und -schutzinteressen. Die Leistung des Betriebsmanagements, einen moglichst hohen Anteil der Nutztiere einer Herde vor klinischen und subklinischen Storungen zu schutzen und Schmerzen, Leiden und Schaden zu vermeiden, wird in diesem Beitrag als „Tierschutzleistung“ eingefuhrt, begrundet und hinsichtlich ihrer Operationalisierbarkeit erlautert. Der Ansatz ermoglicht einen Abgleich zwischen Tierschutz- und Produktionsleistungen innerhalb des Betriebssystems. Gleichzeitig konnen Tierschutzleistungen zwischen Betrieben verglichen und als eine qualitative Leistung des Betriebes auf dem Lebensmittelmarkt angeboten werden.Tierschutzleistungen erfordern von Seiten des Managements, dass die Lebensbedingungen den tierindividuellen Bedurfnissen so angepasst werden, dass deren Anpassungsfahigkeit nicht uberfordert werden, was sich in Gesundheits- und Verhaltensstorungen ausert. Tierschutzleistungen sind das Resultat der Gesamtprozesse in einem Betriebssystem. Um belastbare Aussagen zu Tierschutzleistungen zu generieren, bedarf es eines systemischen sowie funktionalen und ergebnisorientierten Ansatzes. Bislang entscheiden allein die Nutztierhalter daruber, welchen Aufwand sie fur den Schutz von Tieren betreiben und welches Niveau an Tierschutzleistungen dabei erzielt wird. Es wird geschlussfolgert, dass nur uber eine externe Einstufung von Leistungen, die von einem Betriebssystem hinsichtlich des Tierschutzes erbracht werden, der vorherrschende Anthropozentrismus uberwunden und den involvierten Interessensgruppen die bislang fehlende Orientierung zur Erzielung nachhaltiger Verbesserungen des Tierschutzes vermittelt werden kann.
Ami: A Quantitative Approach To Software Management

The ami (Application of Metrics in Industry) initiative was launched with funding from the European Commission in order to raise the profile of measurement in Europe. It comprises a method for implementing measurement programmes based on goal-oriented measurement and process maturity assessment. In this paper we examine ami as a case study in software technology transfer. The dissemination of the method is found to correspond well with models of technology transfer appearing in the literature: analysis of ami using these models is seen to be helpful in shaping future policy for the initiative.
Can the Industry Index Become Another Market Variable? Empirical Evidence from the Listed Banks in Shanghai Stock Exchange

To identify the variables that explain the rate of return of stock, Sharpe developed a simplified single-index model in 1963, and thereafter more models, such as multi-factor model, were constructed to explain the relationship. According to common sense, we can find the common movement of stocks prices in the same industry. Several researchers have found and examined it. In this paper, we construct a new model, which we call the double-index model and introduce a new market variable, which is called the industry index. Through comparison of Adjusted R Squares and correlations of residuals across the bank stocks between the single-index model and the double-index model, we find the industry index improve the explanation power of the model.
REPETITIVE TATTOOING IN BORDERLINE PERSONALITY AND OBSESSIVE-COMPULSIVE DISORDER

This case highlights four important issues: 1.Scrambled egg, along with salt and pepper, effectively masks the taste of clozapine. This, therefore, is a practical method for the surreptitious administration of medication to a noncompliant patient. 2. The above notwithstanding, it is unethical and illegal to treat a patient without his knowledge; this holds true even when the family members of the patient themselves undertake the responsibility for the act. Legally, an unwilling patient can be treated against his will only if committed to psychiatric care through appropriate judicial processes. 3. It is particularly wrong to surreptitiously treat patients with clozapine because blood monitoring for granulocytopenia and agranulocytosis becomes difficult to effect. Current recommendations are that patients be monitored weekly for the initial 6 months, and once in two weeks thereafter (Physicians Desk Reference, 1999). In the case of the present patient, the family took a calculated risk against medical advice, weighing the approximately 0.5% risk of agranulocytosis against the benefits afforded by clozapine. 4. That the family readily obtained clozapine without a medical prescription is an damning indictment of the system of drug availability in the country. There is a pressing need for greater ethical practice amongst pharmaceutical dispensers. Interestingly, the surreptitious administration of clozapine has been reported from other countries as well (Pereira et al., 1999). The* practice of administering medication in food and drink may be widespread in settings such as long stay facilities for the elderly (Treolar et al., 2000). In this contest, Treolar et al. (2001) discussed ethical and related issues, and suggested recommendations on the subject.
A novel reference compensation current strategy for shunt active power filter control

The shunt active power filter has proved to be a useful device to eliminate harmonic currents and to compensate reactive power for linear/nonlinear loads. This paper presents a novel approach to determine reference compensation currents of the three-phase shunt active power filter (APF) under distorted and/or imbalanced source voltages in steady state. The proposed approach is compared with three reviewed shunt APF reference compensation strategies. Results obtained by simulations with Matlab and Simulink show that the proposed approach is more effective than the reviewed approaches on compensating reactive power and harmonic/neutral currents of the load, even if the source voltages are severely distorted and imbalanced. In addition, the proposed approach yields a simpler design of the shunt APF controller.
The social Robotplatform Probo

The past four years a unique robot platform 'Probo' is developed to study cognitive Human-Robot Interaction (HRI). The robot Probo (Saldien, 2009) is designed to act as a social interface, providing a natural interaction while employing human-like social cues and communication modalities. The robot has a fully actuated head, with 20 degrees of freedom, capable of showing facial expressions. Probo embodies a stuffed imaginary animal, providing a soft touch and a huggable appearance. A Robot Control Centre (RCC) enables the operator to control the robot in shared autonomy with the cognitive control of the robot. These cognitive control systems include the simulation of attention, homeostasis, emotional state and the generation of lifelike motions. This project aims to study HRI and Robotic Assisted Therapy (RAT) with a special focus on hospitalized children, a field with growing attention in the robotics community.
Histoire de la lutte contre le phylloxera de la vigne en France

Dans le dernier quart du siecle dernier, la destruction des vignes francaises par un minuscule puceron des racines originaire d'Amerique, le Phylloxera, a ete a l'origine d'une dramatique crise qui a affecte d'abord les regions viticoles meridionales avant de toucher la totalite du vignoble et d'ebranler l'economie nationale toute entiere.Ce n'est qu'apres une tres longue periode de tâtonnements, d'essais et de recherches, marquee par une succession d'echecs et de succes, que les savants et les vignerons francais ont reussi a replanter les vignobles detruits en greffant les cepages europeens traditionnels sur des porte-greffe d'origine americaine. L'exemple francais sera suivi par les autres pays europeens envahis a leur tour par le Phylloxera.Cet ouvrage, a la fois historique et technique, en retracant l'histoire de la lutte longtemps indecise, menee avec acharnement pendant pres de 30 ans contre ce redoutable parasite, presente une des pages les plus fecondes de la collaboration entre les savants et les vignerons de cette epoque, un des premiers et des plus remarquables exemples de contribution de la Sciences a la solution d'un probleme pratique.
Sculpting Via Physical Proxy Using Magnets

I explore the idea of using magnets and ball bearings as a means of sculpting a virtual model via a physical proxy. By using a motion capture system, we can track the position of each bearing, and use them to build a skeleton, which can then be used to construct a 3D model. I attempt to implement a system using open source software that allows users to manipulate a virtual model by physically manipulating magnets and ball bearings. While conceptually rather simple, there were a large number of difficulties that were encountered, and potential solutions for these issues are explored. Finally, Liu explored the use of cameras and physical clay in sculpting virtual objects [Liu 2004].
Intestinal renin–angiotensin system is stimulated after deletion of Lkb1

Background and aims LKB1 is a serine-threonine kinase, mutation of which can lead to the development of multiple benign intestinal hamartomas (Peutz–Jeghers syndrome). In this study, the authors investigate the mechanisms underlying this phenotype by exploring the transcriptional changes associated with Lkb1 deletion in intestinal epithelium. Methods The authors used mice with Lkb1 deleted in the intestinal epithelium using a Cyp1a1-specific inducible Cre recombinase and used Affymetrix (Santa Clara, California, USA) microarray analysis to examine the transcriptional changes occurring immediately after Lkb1 loss. The authors also generated crypt–villus organoid culture to analyse Lkb1 role in intestinal responses to exogenous stimuli. Results Affymetrix analysis identified the most significant change to be in Ren1 expression, a gene encoding a protease involved in angiotensinogen processing. Lkb1 deletion also enhanced ACE expression and subsequently angiotensin II (AngII) production in the mouse intestine. Intestinal apoptosis induced by Lkb1 deficiency was suppressed by ACE inhibitor captopril. Lkb1-deficient intestinal epithelium showed dynamic changes in AngII receptor type 1, suggesting a possible compensatory response to elevated AngII levels. A similar reduction in epithelial AngII receptor type 1 was also observed in human Peutz–Jeghers syndrome tumours contrasting with high expression of the receptor in the tumour stroma. Mechanistically, the authors showed two pieces of data that position Lkb1 in renin expression regulation, and they implied the importance of Lkb1 in linking cell responses with nutrient levels. First, the authors showed that Lkb1 deletion in isolated epithelial organoid culture resulted in renin upregulation only when the organoids were challenged with external cues such as AngII; second, that renin upregulation was dependent upon the MEK/ERK pathway in a circadian fashion and corresponded to active feeding time when nutrient levels were high. Conclusions Taken together, these data reveal a novel role for Lkb1 in regulation of the gastrointestinal renin–angiotensin system.
Occurrence and Phenotypic Characteristics of Extended-Spectrum β-Lactamases among Members of the Family Enterobacteriaceae at the Tel-Aviv Medical Center (Israel) and Evaluation of Diagnostic Tests

ABSTRACT We assessed the prevalence and phenotypic characteristics of extended-spectrum β-lactamase (ESBL) producers among cefuroxime-resistant (CXM-R) (MIC ≥ 32 μg/ml) members of the family Enterobacteriaceae in our institution. The 438 CXM-R clinical isolates obtained from nonurine sources among inpatients were screened. ESBL production was confirmed by disk diffusion assay using cefpodoxime (CPD), cefotaxime (CTX), and ceftazidime (CTZ) with and without clavulanate (CLAV). A difference of ≥5 mm in the size of the zone of inhibition in the presence of CLAV for at least one of the agents was considered representative of the ESBL phenotype: 186 isolates (42.5%) were confirmed as ESBL producers. The isolates tested and the rates of ESBL producers were as follows: Klebsiella spp. (n = 81), 79%; Proteus spp. (n = 58), 62%; Escherichia coli (n = 64), 53%; Enterobacter spp. (n = 69), 42%; Serratia spp. (n = 70), 14%; Citrobacter spp. (n = 25), 24%; Providencia spp. (n = 21), 24%; Morganella spp. (n = 41), 5%; and Kluyvera (n = 3), 0%. The overall sensitivity of isolated ESBL confirmatory tests was 79% for CPD-CLAV, 66% for CTZ-CLAV, and 91% for CTX-CLAV. Sensitivities of CTZ-CLAV confirmatory tests for Klebsiella spp. , Proteus spp. , E. coli, and Enterobacter spp. were 84, 22, 76, and 62%, respectively, and those for CTX-CLAV were 95, 97, 94, and 83%, respectively. They were 90% for CPD-CLAV and CTZ-CLAV, 95% for CPD-CLAV and CTX-CLAV, and 100% for CTZ-CLAV and CTX-CLAV. ESBL production was highly prevalent among Enterobacteriaceae. Using resistance to CXM as an ESBL screening criterion is a suitable option in high-incidence areas where Klebsiella spp. are not the dominant ESBL producers. This screening criterion may simplify the screening test and improve its sensitivity, although at the price of testing more isolates. The CTX-CLAV combination confirmed ESBL producers better than the CTZ-CLAV combination, with sensitivity varying between species. Combined CTZ-CLAV and CTX-CLAV testing detected all these strains; CPD-CLAV provided no additional benefit.
Robust model predictive control of a laboratory two-tank system

Robust model predictive control was applied for the laboratory two-tank system. The controlled process is modeled as the uncertain polytopic system for the controller design. Two robust model predictive control design strategies were used. The first strategy uses the single Lyapunov function and the second one assumes the parameter-dependent Lyapunov functions. The design problem is converted to the solution of the system of linear matrix inequalities and a simple algorithm is also presented. The controllers designed using both strategies were tested on the laboratory process. The results confirmed that using the parameter-dependent Lyapunov function in the robust model predictive controller design improved the control performance in comparison with the single Lyapunov function based strategy.
Characteristics of women who have repeat abortions in the Netherlands

Abstract Objectives To explore the demographic characteristics of women having multiple abortions, in order to identify abortion clients who might be at increased risk of repeat abortion. Methods On the basis of the registration data of most Dutch abortion clinics, responsible for 64% of all such procedures, women who procured a first abortion were compared to those who had one or more previously. Results of bivariate analyses and a multivariate binary logistic regression analysis are presented. Results Of all abortions, 36% were repeat abortions. Women aged over 20 were more likely to have repeat abortions, as were migrants, particularly those with a Caribbean background (from Surinam or the Netherlands Antilles) and women who had children. Effect sizes of other factors were very small. Surprisingly, women who had repeat abortions more often used contraception in the preceding six months than women who had a first abortion, but also this effect size was small as well. A multivariate logistic regression analysis led to similar results. Conclusions Abortion clients with a Caribbean background should be targeted for the prevention of more unwanted pregnancies. Not only should the use of reliable contraception be promoted, but also compliance and continuation.
Teaching undergraduate algorithms with case studies and quizzes in interactive tutorials

The subject of algorithms is a core component of Computer Science for undergraduate students. Many of innovative teaching methods have been proposed in the literature and practiced in classrooms aiming to help students learn the subject effectively. This paper reports on our experience in teaching advanced data structures and classic computer science algorithms for year 2 students. For three consecutive years, we practiced a different teaching approach each year. The details of each approach are provided and discussed. By comparing students' learning performance, we found that teaching undergraduate algorithms with case studies and quizzes in interactive tutorials is relatively more beneficial for effective teaching and learning. We conclude the paper with a short summary and future work.
Gastrointestinal motility and gastric tube feeding in mechanically ventilated patients.

OBJECTIVE To determine the fasted and fed gastrointestinal motility characteristics that are possibly responsible for gastric retention in mechanically ventilated patients. DESIGN Prospective, case series. SETTING Surgical intensive care unit of a university hospital. PATIENTS Seven patients who required mechanical ventilation for thoracic or combined thoracic-neurologic injuries and nine healthy volunteers. INTERVENTIONS None. MEASUREMENTS AND MAIN RESULTS Antroduodenal manometry was performed during fasting and gastric feeding with a polymeric diet in patients during mechanical ventilation, weaning, and after detubation. Gastric retention volumes were determined during gastric tube feeding. Motility data were compared with recordings from nine healthy volunteers. During the fasting state, under sedation and morphine, the migrating motor complex in patients was significantly (p < .001) shortened: median 32.0 vs. 101.0 mins in healthy volunteers. During gastric tube feeding, the motility pattern did not convert to a normal postprandial pattern until morphine was discontinued. An interdigestive or mixed interdigestive-postprandial pattern was seen during gastric tube feeding in most patients during morphine administration. Most (94%) of the activity fronts during gastric feeding started in the duodenum. Gastric retention percentages during gastric tube feeding were negatively correlated (r2=.44; p < .01) with antral motor activity. CONCLUSIONS These data suggest that morphine administration affects antroduodenal motility in mechanically ventilated patients. The gastrointestinal motor pattern involved in impaired gastric emptying in morphine-treated patients is characterized by antral hypomotility and persisting duodenal activity fronts during continuous intragastric feeding. The observed motility patterns suggest that early administration of enteral feeding might be more effective into the duodenum or jejunum than into the stomach of mechanically ventilated patients.
Circularly Polarized Slotted Waveguide Array With Improved Axial Ratio Performance

This communication demonstrates experimentally the improvement in axial ratio performance when a slot is combined with a set of three parasitic dipoles instead of one. The analysis is performed in the context of slotted-waveguide arrays and SATCOM applications in Ka band, where a bandwidth specification as wide as 7.5% can be demanded.
Digital audio watermarking and its application in multimedia database

In this paper, the general frame of audio watermarking and the current watermarking techniques and their applications are presented. In order to improve the inaudibility and robustness in watermark embedding and extraction, we proposed an adaptive content-based audio watermarking scheme. Finally, the evaluations for various audio watermarking techniques are given.