Miracle-dz/UniFAR-FTUs huggingface dataset:
Generating Vector Spaces On-the-fly for Flexible XML Retrieval

While documents are flat with conventional information retrieval, i.e., they are unstructured information, this is no longer adequate with semistructured data such as XML for two reasons. First, XML allows to hierarchically structure information within a document such that each document has tree structure. Users in turn want to refer to this structure when searching for relevant information. To do so, users pose so-called content-and-structure queries. Such queries refer to the document structure, e.g., by restricting the context of interest to some XML elements. Relevance ranking consequently has to properly reflect both document structure and the constraints that the query poses on the structure. Namely, the contents at the different levels of the tree are considered of different importance for a query. The intuition behind this is that content that is more distant in the document tree is less important than the one that is close to the context node. We subsequently denote this concept as nested retrieval, and it is a crucial requirement for meaningful retrieval from XML documents. Fuhr et al. tackle this issue by a technique denoted as augmentation [2, 3]. The idea is to introduce so-called augmentation weights that downweigh statistics such as inverted document frequencies of terms when the terms are propagated upwards in the document tree. To do so, Fuhr et al. [3] group XML element types to so-called indexing nodes that implement the inverted lists for efficient retrieval. They constitute the granularity of retrieval with their approach, i.e., indexes and statistics such as document frequencies are derived separately per indexing node. Users can search at the granularity of the indexing nodes and hierarchical combinations of them if indexing nodes are along the same path in the document. Term weights are properly augmented in this case. The drawback of the approach is that the assignment of XML element types to indexing nodes is static. Hence, users cannot retrieve dynamically, i.e., at query time, from arbitrary combinations of element types. The second reason why conventional retrieval techniques do not suffice for XML retrieval is that even a single XML document may have very heterogeneous content. Take for instance
Dermatonutrigenomics: Past, Present, and Future

Past The notion of nutrigenomics arose at the dawn of the genome sequencing era. In 1999, a prolific study by Lee et al. [5] published in Science suggested that gene expression profiles can be used as mechanistic tools to better understand the effects of environmental factors and nutritional interventions (e.g., caloric restriction) on health. Completion of the Human Genome Project in 2001 provided a framework for documenting single-nucleotide polymorphisms (SNPs) in candidate genes and exploring metabolic imbalances, sparking numerous research studies across all organ systems [3]. By that time, individual genetic differences in response to dietary components had been evident for years (e.g., lactose intolerance). In 2005, the term “nutrigenomics” first appeared in the dermatologic literature in an article on psoriasis patients in Archives of Dermatology. Treloar [2] described the role of the SNP C677T in the gene for methylene tetrahydrofolate reductase (MTHFR), an enzyme critical in the activation and regeneration of folate. Psoriasis patients have significantly elevated homocysteine levels and lower folate levels compared with matched controls, which correlated with an increased risk of atherosclerotic disease [2]. This study sparked interest in the role of dietary modulation and supplementations of folate, cyanocobalamin, and/or pyridoxine for cardioprotection. In 2010, Subbiah [3] coined “dermagenetics,” which involves testing for select genetic mutations related to skin health and recommending the use of nutraceuticals or cosmeceuticals based on the individual results. The common mutations examined are related to the enzymes involved in: (a) collagen breakdown, (b) photoaging and free oxygen radical elimination, (c) degradation of environmental pollutants, and (d) generation of proinflammatory molecules [3]. The benefit of such cosmeceuticals is currently heavily under debate given our lack of understanding of their formulation methods, the integrity of the active ingredients, release from carrier vehicles, and limited FDA regulation (Fig. 1).
Does the Stress of Laboratory Life and Experimentation on Animals Adversely Affect Research Data? A Critical Review

Recurrent acute and/or chronic stress can affect all vertebrate species, and can have serious consequences. It is increasingly and widely appreciated that laboratory animals experience significant and repeated stress, which is unavoidable and is caused by many aspects of laboratory life, such as captivity, transport, noise, handling, restraint and other procedures, as well as the experimental procedures applied to them. Such stress is difficult to mitigate, and lack of significant desensitisation/habituation can result in considerable psychological and physiological welfare problems, which are mediated by the activation of various neuroendocrine networks that have numerous and pervasive effects. Psychological damage can be reflected in stereotypical behaviours, including repetitive pacing and circling, and even self-harm. Physical consequences include adverse effects on immune function, inflammatory responses, metabolism, and disease susceptibility and progression. Further, some of these effects are epigenetic, and are therefore potentially transgenerational: the biology of animals whose parents/grandparents were wild-caught and/or have experienced chronic stress in laboratories could be altered, as compared to free-living individuals. It is argued that these effects must have consequences for the reliability of experimental data and their extrapolation to humans, and this may not be recognised sufficiently among those who use animals in experiments.
Amniotic fluid and placental stem cells as a source for urological regenerative medicine

Stem cells capable of differentiating to multiple lineages may be valuable for urological regenerative medicine. Recent research has described the presence in the amniotic fluid of stem cells with various differentiative and proliferative potentials. The use of amniotic fluid-derived stem cells does not present the same ethical challenges as the use of embryonic stem cells and the cells can be isolated using amniocentesis, a widely accepted procedure for prenatal diagnosis. This chapter summarizes the different progenitor cells that have been described so far in the amniotic fluid and the placenta and focuses in particular on mesenchymal stem cells and amniotic fluid-derived stem cells. © 2009 Woodhead Publishing Limited. All rights reserved.
VLSI datapath choices : cell-based versus full-custom

Traditionally, VLSI architects and designers have acknowledged the area, performance , and eeort tradeoos between cell-based and full-custom implementations of the same datapath function. However, few attempts have been made to characterize these tradeoos in the context of contemporary fabrication processes and area place and route tools. More importantly, few attempts have been made to determine how to enable cell-based implementations to approach the density and speed of full-custom designs. This work quantiies the limits of cell-based datapath implementations based on results derived from a detailed analysis of the density and performance tradeoos in the implementation of two full-custom datapaths, the Integer Register-Read Datapath (IRRDP) and the 64-bit adder/subtracter (ADDSUB), employed in the multi-ALU Processor (MAP) chip. A cell-based implementation of the IRRDP is 1.64x larger than the full-custom original. The critical timing path for the cell-based implementation is 11% longer. The cell-based implementation of the ADDSUB is 1.74x larger, however, the critical timing path is only 17% longer. Both of these implementations are signiicant improvements over a traditional ASIC approach. The traditional ASIC implementation of the IRRDP is 14.5x larger and has 123% longer critical path. The best ASIC implementation of the ADDSUB is 1.67x larger and has a 170% longer critical path. Also, this work identiies a new physical design eeciency metric (layout) based on a linear combination of area utilization (gate) and device utilization (t).
Empirical Memory-Access Cost Models in Multicore NUMA Architectures

Data location is of prime importance when scheduling tasks in a non-uniform memory access (NUMA) architecture. The characteristics of the NUMA architecture must be understood so tasks can be scheduled onto processors that are close to the task's data. However, in modern NUMA architectures, such as AMD Magny-Cours and Intel Nehalem, there may be a relatively large number of memory controllers with sockets that are connected in a non-intuitive manner, leading to performance degradation due to uninformed task-scheduling decisions. In this paper, we provide a method for experimentally characterizing memory-access costs for modern NUMA architectures via memory latency and bandwidth microbenchmarks. Using the results of these benchmarks, we propose a memory-access cost model to improve task-scheduling decisions by scheduling tasks near the data they need. Simple task-scheduling experiments using the memory-access cost models validate the use of empirical memory-access cost models to significantly improve program performance.
Rol independiente y ambiente de la práctica de enfermería

Introduccion: las enfermeras desempenan los roles independiente, dependiente e interdependiente para cuidar, el ambiente de la practica afecta directamente el desempeno de dichos roles y asi los resultados del cuidado. Objetivo: comparar el desempeno del rol independiente de las enfermeras y el ambiente de la practica en un grupo de servicios de hospitalizacion de instituciones clinicas publicas y privadas de segundo y tercer nivel de atencion de dos ciudades de Colombia. Metodos: estudio descriptivo comparativo, muestra intencionada de 210 enfermeras. Para la recoleccion de la informacion se utilizo la Encuesta Multinacional sobre la Relacion entre el Rol Profesional de la Enfermera (o) y su lugar de trabajo y para el analisis se emplearon estrategias de analisis univariado y bivariado. Resultados: el 72 % de las enfermeras refirio que su rol principal es supervisar la atencion de otros. Sin diferir de manera significativa segun caracter de la institucion, las enfermeras dedican gran parte de su tiempo a realizar acciones no relacionadas directamente con su rol profesional limitando el tiempo para el cuidado directo. Existe diferencia entre las instituciones clinicas publicas y las privadas con respecto a la calificacion que las enfermeras otorgan al ambiente de la practica de su institucion (valor p: 0.000). Conclusion: se identifico la necesidad de evaluar la ejecucion del rol independiente y los factores del ambiente de la practica para implementar medidas que contribuyan a mejorar la calidad y seguridad del cuidado.
Epidemiology of Children’s Individual Sports Injuries

Participation in children’s and youth sports is increasingly popular and widespread in Western culture. Many of these youngsters initiate year-round training and specialization in their sports at a very early age. This is probably due to the ‘catch them young’ philosophy, and to the belief that, to achieve international standing in later sporting life, intensive training should be started before puberty [1]. It is not uncommon today, for example, for preteens to train 20 or more hours each week at regional training centers in tennis or gymnastics, to compete in triathlons, or for youngsters as young as 6–8 years of age to play organized hockey or soccer and travel with select teams to other towns and communities to compete against other teams of similar caliber.
Risk and prognostic factors for endometrial carcinoma after diagnosis of breast or Lynch‐associated cancers—A population‐based analysis

We hypothesized that endometrial carcinoma (EC) patients with a prior cancer diagnosis, after accounting for EC arising after tamoxifen‐treated prior breast carcinoma, are more likely to have an underlying genetic basis. We used information from a population‐based study to compare measured risk factors, tumor characteristics, survival, and known mismatch repair (MMR) pathogenic variant status for EC subgroups according to prior diagnosis of cancer (none, breast cancer tamoxifen‐treated or not, Lynch Syndrome (LS)‐associated cancer). Family history of any cancer was increased for EC cases with prior breast cancer, both tamoxifen treated (P = 0.005) and untreated (P = 0.01). EC cases with prior LS‐associated cancer more often reported family history of LS‐associated cancer (P = 0.04) and breast cancer (P = 0.05). EC patients with a germline pathogenic MMR gene variant were more likely to report a prior cancer than cases with a MMR proficient tumor (P = 0.0001), but more than half (54.5%) of MMR carriers reported no prior cancer. Women developing EC after tamoxifen treatment for breast cancer were significantly more likely to develop EC of malignant mixed mullerian tumor subtype (13.2% vs 2.6%, P = 1.3 × 10−6), present with stage IV disease (8.8% vs 1.2%, P = 1.6 × 10−6), and have poorer survival (HRadj 1.96; P = 0.001). While report of prior cancer is an indicator of MMR pathogenic variant status, molecular analysis of all ECs at diagnosis is warranted to detect all patients with LS. Results also indicate the importance of longer‐term monitoring of women treated with tamoxifen for symptoms of EC, and the need for studies assessing the biological mechanism underlying the poorer prognosis of this subset of EC patients.
Utilisation péri-opératoire des corticoïdes en chirurgie buccale

En chirurgie buccale, les interventions sont tres frequemment associees a un processus inflammatoire postoperatoire plus ou moins intense et invalidant, incluant douleur, oedeme et trismus. Le controle de ce processus passe principalement par la prescription de molecules anti-inflammatoires, parmi elles les anti-inflammatoires steroidiens ou corticoides. Les corticoides sont des substances qui permettent a la fois d’attenuer les consequences fonctionnelles, esthetiques et douloureuses pour le moins fâcheuses de la chirurgie, mais ils peuvent presenter de nombreux effets deleteres, surtout lors de l’utilisation a long terme, limitant leur utilisation. Plusieurs etudes recentes ont montre la securite et l’efficacite de l’utilisation a court terme des glucocorticoides en chirurgie buccale, notamment dans certaines situations cliniques telles que les dents incluses, les extractions multiples, les vestibuloplasties, les resections d’os, et d’autres cas similaires. Ces etudes ont egalement permis de mieux comprendre leur mode d’action et de proposer une attitude coherente pour leur prescription en chirurgie buccale.
Effect of 12 weeks of yoga practice on glucose, insulin and triglycerides serum level in women with diabetes type II

Background and Objective: Diabetes mellitus is one of the most common serious met abolic disorders. This study was done to determine the effect of 12-week yoga intervention on glucose, insulin and triglyceride serum levels in women with type II diabetes mellitus. Materials and Methods: In this clinical trial, 26 women with Type II diabe tes were divided into interventional (n=16) and control groups (n=10). Program of yoga exercise including: 75 minutes daily, three sessions in a week, and for 12 weeks. The level of glucose, insulin, leptin, HDL -C, LDL -C, triglyceride, total cholesterol were measured prior and post - training period. Results: The levels of glucose, insulin and triglycerides in the interventional group significant ly reduced compared to control group following the training period (P<0.05). The level of leptin, HDL-C, LDL -C, total cholesterol was not significantly altered in intervention group in compare to controls. Conclusion: 12 weeks of yoga exercises can improve blood glucose, insulin and triglyceride in women with type II diabetes. _____________________________________________________________________________________________________________________________
Ortaokul Öğretmenlerinin Örgütsel Sessizlik Algıları

Arastirmanin amaci, ortaokullarda gorev yapan ogretmenlerin orgutsel sessizlik algilarini belirlemek ve orgutsel sessizlik algilarinin bagimsiz degiskenler acisindan farklilik gosterip gostermedigini belirlemektir. Arastirma, betimsel niteliktedir ve arastirmada genel tarama modeli kullanilmistir. Arastirmanin evrenini 2017-2018 egitim-ogretim yilinda Malatya ili Yesilyurt ilcesinde gorev yapan ortaokul ogretmenleri olusturmaktadir. Arastirmada kolayda ornekleme yontemi kullanilmistir. Orneklem 232 ogretmenden olusmaktadir. Veri toplama araci olarak Kahveci ve Demirtas tarafindan gelistirilen “Orgutsel Sessizlik Olcegi” kullanilmistir. Degiskenler arasinda anlamli fark olup olmadigini belirlemek icin t testi ve tek yonlu varyans analizi yapilmistir. Arastirmada ortaokul ogretmenlerinin orgutsel sessizlik algilari orta duzeyde cikmistir. Orgutsel sessizlik algisi okul ortami ve sessizligin kaynagi alt boyutunda orta duzeyde; duygu, yonetici ve izolasyon alt boyutunda yuksek duzeyde cikmistir Orgutsel sessizlik algilari; cinsiyet, medeni durum, ogrenim durumu, brans ve mesleki kidem degiskenlerine gore anlamli farklilik gostermemektedir. Sadece ogrenim durumu degiskene gore duygu alt boyutunda anlamli farklilik gostermektedir. Bu farklilik su sekildedir; lisansustu mezunu ogretmenler lisans mezunu ogretmenlere oranla daha fazla orgutsel sessizlik yasamaktadir.
Course-of-Value Induction in Cedille

In the categorical setting, histomorphisms model a course-of-value recursion scheme that allows functions to be defined using arbitrary previously computed values. In this paper, we use the Calculus of Dependent Lambda Eliminations (CDLE) to derive a lambda-encoding of inductive datatypes that admits course-of-value induction. Similar to course-of-value recursion, course-of-value induction gives access to inductive hypotheses at arbitrary depth of the inductive arguments of a function. We show that the derived course-of-value datatypes are well-behaved by proving Lambek's lemma and characterizing the computational behavior of the induction principle. Our work is formalized in the Cedille programming language and also includes several examples of course-of-value functions.
Achieving High Performance on the i860 Microprocessor

The i860 is a high performance microprocessor used in the Intel Touchstone project. This paper proposes a paradigm for programming the i860 that is modelled on the vector instructions of the Cray computers. Fortran callable assembler subroutines were written that mimic the concurrent vector instructions of the Cray. Cache takes the place of vector registers. Using this paradigm we have achieved twice the performance of compiled code on a traditional solve.
Role of immunotherapy in stage III nonsmall cell lung cancer

Purpose of review Despite aggressive treatment based on definitive chemoradiotherapy, 5-year overall survival in unresectable stage III nonsmall cell lung cancer remains poor (15–20%). The novel immunotherapy based on immune checkpoint inhibitors (ICIs) presents as the therapeutic ‘Holly Grail’ in lung cancer treatment. Recent findings Preclinical models provide evidence of immunotherapy–radiotherapy (IM-RT) synergy. The exposure to ionizing radiation turns tumor in an in-situ vaccine, primes the innate immune system, increases immunotherapy efficacy by overcoming the immunosuppressive microenvironment of immune-resistant tumors and promotes a systemic, out-of-field antitumor T-cell-mediated response called abscopal effect. The immunomodulatory and abscopal effects of radiotherapy can be further enhanced by combining with systemic immunotherapies. The phase III START trial proved that liposomal vaccine – tecemotide (L-BLP25) administered as maintenance therapy after concurrent chemoradiotherapy (CRT) in LA-NSCLC prolongs survival. In the phase III PACIFIC trial consolidation with durvalumab, an anti-PDL-1 antibody, was associated with survival benefit in patients diagnosed with LA-NSCLC who responded to concurrent chemoradiotherapy. Summary PACIFIC trial results are expected to definitely establish durvalumab as standard consolidation strategy in LA-NSCLC. Many clinical trials are ongoing in the field of immunoradiotherapy in LA-NSCLC to define the optimal conditions for this therapeutic combination.
Handbook of Geometric Computing: Applications in Pattern Recognition, Computer Vision, Neuralcomputing, and Robotics

Neuroscience. - Spatiotemporal Dynamics of Visual Perception Across Neural Maps and Pathways. - Symmetry, Features, and Information. - Neural Networks. - Geometric Approach to Multilayer Perceptrons. - A Lattice Algebraic Approach to Neural Computation. - Eigenproblems in Pattern Recognition. - Image Processing. - Geometric Framework for Image Processing. - Geometric Filters, Diffusion Flows, and Kernels in Image Processing. - Chaos-Based Image Encryption. - Computer Vision. - One-Dimensional Retinae Vision. - Three-Dimensional Geometric Computer Vision. - Dynamic % MathType! MTEF! 2! 1! +- % feaafiart1ev1aaatCvAUfeBSjuyZL2yd9gzLbvyNv2CaerbuLwBLn % hiov2DGi1BTfMBaeXafv3ySLgzGmvETj2BSbqefm0B1jxALjhiov2D % aebbnrfifHhDYfgasaacH8srps0lbbf9q8WrFfeuY-Hhbbf9v8qqaq % Fr0xc9pk0xbba9q8WqFfea0-yr0RYxir-Jbba9q8aq0-yq-He9q8qq % Q8frFve9Fve9Ff0dmeaabaqaciGacaGaaeqabaWaaeaaeaaakeaatu % uDJXwAK1uy0HwmaeHbfv3ySLgzG0uy0Hgip5wzaGqbaiab-9q8qnaa % CaaaleqabaWexLMBb50ujbqehq0BYngALnhDLjhitnMCPbhDG0evaG % GbaKqzafGae4NBa4gaaaaa! 4FF9! $$\mathcal{P}^n $$ to % MathType! MTEF! 2! 1! +- % feaafiart1ev1aaatCvAUfeBSjuyZL2yd9gzLbvyNv2CaerbuLwBLn % hiov2DGi1BTfMBaeXafv3ySLgzGmvETj2BSbqefm0B1jxALjhiov2D % aebbnrfifHhDYfgasaacH8srps0lbbf9q8WrFfeuY-Hhbbf9v8qqaq % Fr0xc9pk0xbba9q8WqFfea0-yr0RYxir-Jbba9q8aq0-yq-He9q8qq % Q8frFve9Fve9Ff0dmeaabaqaciGacaGaaeqabaWaaeaaeaaakeaatu % uDJXwAK1uy0HwmaeHbfv3ySLgzG0uy0Hgip5wzaGqbaiab-9q8qnaa % CaaaleqabaWexLMBb50ujbqehq0BYngALnhDLjhitnMCPbhDG0evaG % GbaKqzafGae4NBa4gaaaaa! 4FF9! $$\mathcal{P}^n $$ Alignment. - Detecting Independent 3D Movement. - Perception and Action. - Robot Perception and Action Using Conformal Geometric Algebra. - Uncertainty in Geometric Computations. - Uncertainty Modeling and Geometric Inference. - Uncertainty and Projective Geometry. - The Tensor Voting Framework. - Computer Graphics and Visualization. - Methods for Nonrigid Image Registration. - The Design of Implicit Functions for Computer Graphics. - Geometry and Robotics. - Grassmann-Cayley Algebra and Robotics Applications. - Clifford Algebra and Robot Dynamics. - Geometric Methods for Multirobot Optimal Motion Planning. - Reaching and Motion Planning. - The Computation of Reachable Surfaces for a Specified Set of Spatial Displacements. - Planning Collision-Free Paths Using Probabilistic Roadmaps.
Infoglut: How Too Much Information Is Changing the Way We Think and Know

Today, more mediated information is available to more people than at any other time in human history. New and revitalized sense-making strategies multiply in response to the challenges of "cutting through the clutter" of competing narratives and taming the avalanche of information. Data miners, "sentiment analysts," and decision markets offer to help bodies of data "speak for themselves"making sense of their own patterns so we dont have to. Neuromarketers and body language experts promise to peer behind peoples words to see what their brains are really thinking and feeling. New forms of information processing promise to displace the need for expertise and even comprehensionat least for those with access to the data. Infoglut explores the connections between these wide-ranging sense-making strategies for an era of information overload and "big data," and the new forms of control they enable. Andrejevic critiques the popular embrace of deconstructive debunkery, calling into question the post-truth, post-narrative, and post-comprehension politics it underwrites, and tracing a way beyond them.