Miracle-dz/UniFAR-FTUs huggingface dataset:
Phenotypic Characterization of a Major Quantitative Disease Resistance Locus for Partial Resistance toPhytophthora sojae

Major quantitative disease resistance loci (QDRLs) are rare in the Phytophthora sojae (Kaufmann and Gerdemann)–soybean [Glycine max (L). Merr. ] pathosystem. A major QDRL on chromosome 18 (QDRL-18) was identified in PI 427105B and PI 427106. QDRL-18 represents a valuable resistance source for breeding programs. Thus, our objectives were to determine its isolate specificity and measure its effect on yield and resistance to both P. sojae and other soybean pathogens. We characterized near isogenic lines (NILs) developed from F7 recombinant inbred lines heterozygous at QDRL-18; NILs represent introgressions from PI 427105B, PI 427106, and susceptible ‘OX208’. The introgressions from PI 427105B and PI 427106 increased resistance to P. sojae by 11 to 20% and 35 to 40%, respectively, based on laboratory and greenhouse assays, and increased yield by 13 to 29% under disease conditions. The resistant introgression from PI 427105B was also effective against seven P. sojae isolates with no isolate specificity detected. Based on quantitative polymerase chain reaction assays, NILs with the susceptible introgression had significantly higher relative levels of P. sojae colonization 48 h after inoculation. No pleiotropic effects for resistance to either soybean cyst nematode or Fusarium graminearum were detected. This information improves soybean breeders’ ability to make informed decisions regarding the deployment of QDRL-18 in their respective breeding programs. S. Karhoff, Center for Applied Plant Sciences, and The Ohio State Univ. Center for Soybean Research, 2021 Coffey Rd., Columbus, OH 43210; S. Lee, Dep. of Crop Science, Chungnam National Univ., Daejeon, South Korea 34134; M.A.R. Mian, USDA-ARS Soybean Research Unit, 3127 Ligon St., Raleigh, NC 27607; T.I. Ralston and T.L. Niblack, Dep. of Plant Pathology, 2021 Coffey Rd., Columbus, OH 43210; A.E. Dorrance, Dep. of Plant Pathology, Center for Applied Plant Sciences, and The Ohio State Univ. Center for Soybean Research, 1680 Madison Ave., Wooster, OH 44691; L.K. McHale, Dep. of Horticulture and Crop Science, Center for Applied Plant Sciences, and The Ohio State Univ. Center for Soybean Research, 2021 Coffey Rd. Columbus, OH 43210. Received 23 Aug. 2018. Accepted 6 Feb. 2019. *Corresponding author (mchale.21@osu.edu). Assigned to Associate Editor Eric Olson. Abbreviations: hai, hours after inoculation; HG, Heterodera glycines; NIL, near isogenic line; qPCR, quantitative polymerase chain reaction; QDRL, quantitative disease resistance locus; RIL, recombinant inbred line; SSR, simple sequence repeat; SNP, single nucleotide polymorphism; SCN, soybean cyst nematode. Published in Crop Sci. 59:968–980 (2019). doi: 10.2135/cropsci2018.08. 0514 © 2019 The Author(s). This is an open access article distributed under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Published May 16, 2019
RECOMPILAÇÃO DO NÚCLEO COMO ATIVIDADE PRÁTICA NO GERENCIAMENTO DE “CHAMADAS DE SISTEMAS” NO ENSINO DE SISTEMAS OPERACIONAIS

This article proposes a practical experience in the teaching of Operating Systems, specifically in the demonstrations of the theme: “System Calls”, whose goal is to present to the student the experience of executing a code that performs a system call, as well as the code that responds to the system call, evidencing the change of control flow between the user level and the core level. The article describes the practical experience of simple achievement that results in great benefits for learning the theme.
Activity Pattern Aware Spectrum Sensing: A CNN-Based Deep Learning Approach

In cognitive radio, most spectrum sensing algorithms are model-based and their detection performance relies heavily on the accuracy of the assumed statistical model. In this letter, we propose a convolutional neural network-based deep learning algorithm for spectrum sensing. Compared with model-based spectrum sensing algorithms, our proposed deep learning approach is data-driven and requires neither signal-noise probability model nor primary user (PU) activity pattern model. The proposed algorithm simultaneously takes in the present sensing data and historical sensing data, with which the inherent PU activity pattern can be learned to benefit the detection of PU activity. With extensive numerical simulations, results show that the proposed algorithm outperforms the estimator-correlator detector and the hidden Markov model-based detector in terms of correct detection probability.
Stability of EEG laterality effects.

Task related interhemispheric asymmetries of ongoing EEG activity (alpha band) were tested for stability across three separate occasions. Seven cognitive tasks, presumed to differentially engage either the left or right cerebral hemisphere, were presented to 6 subjects. Involvement with the tasks was determined by evaluation of performance and with a subjective report on degree of involvement. Bilateral EEG was recorded over the parietal areas referenced to an ipsilateral ear, vertex and a central placement, on separate channels. Spectral intensity estimates of 8–13 Hz activity were used to form left/right ratios for determination of asymmetry. Intra-subject stability of alpha band activity was found to improve with the establishment of task validity and to be related to the electrode placement used.
Determining a Patient’s Comfort in Inquiring About Healthcare Providers’ Hand-Washing Behavior

Objectives To determine whether a patient’s level of assertiveness and other factors influences her comfort level in asking her provider to wash his or her hands. Methods In this pilot study, we developed a survey to gather cross-sectional information on a variety of factors that might explain patient willingness to ask her health-care provider to wash his or her hands. Three primary predictor variables are analyzed: (1) patient assertiveness; (2) patient familiarity with her healthcare provider; and (3) whether the patient has observed hand-washing behavior. Fifty patients participated from the Obstetrics and Gynecology Department of Metropolitan Hospital Center. Results Less assertive patients are much less likely than assertive patients to ask physicians to wash hands (25% versus 68%; Fisher’s exact test P = 0.0427). Among the 3 assertiveness questions included in the survey, the ability to ask physicians questions during visits is most strongly indicative of willingness to ask about hand washing. Familiarity with the names of regular health-care providers has a statistically significant impact on willingness to ask about hand washing. Evidence suggests that observing hand washing behavior affects willingness to ask, but differences are not statistically significant. Results by socioeconomic status such as age, education, income, and race/ethnicity are inconclusive. Conclusions A patient’s level of assertiveness alone is not sufficient to determine her willingness to inquire about the hand-washing behavior of her provider. A high percentage of patients did not see their provider engaging in adequate hand washing behavior. If patients feel comfortable with their provider to inquire about their care and request hand-washing behavior, health outcomes are affected by reducing the rates of health care–associated infections.
Frequency reconfigurable antenna using PIN diodes

A compact frequency reconfigurable double slot antenna for wireless communication is presented. The proposed antenna consists of double slot with six RF PIN diodes placed at different position on the ground plane to achieve frequency reconfigurability. Based on the switching state of the PIN diode the antenna is capable of operating at eleven different frequency ranges. The radiation pattern of the antenna is nearly omnidirectional for all the frequency bands. The simulated return loss for all the frequency bands meets the optimum value. The overall dimension of the antenna is 30 × 25mm2 including ground plane. For different switching state, the antenna can operate in both single and dual band mode. Without changing the size of the antenna the antenna can operate in single band and dual band mode by changing the state of the RF PIN diode. The antenna parameters such as VSWR return loss and radiation pattern are simulated. The analyses are performed using Ansoft HFSS v13.0 software.
Telomeres and telomerase in normal and malignant B‐cells

The telomeric checkpoint is emerging as a critical sensor of cellular damage, playing a major role in human aging and cancer development. In the meantime, telomere biology is rapidly evolving from a basic discipline to a translational branch, capable of providing major hints for biomarker development, risk assessment and targeted treatment of cancer. These advances have a number of implications in the biology of lymphoid tumours. Moreover, there is considerable interest in the potential role of telomeric dysfunction in the wide array of immunological abnormalities, grouped under the definition of ‘immunosenescence’. This review will summarize the impact of recent advances in telomere biology on the physiology and pathology of the B lymphocyte, with special interest in immunosenescence and lymphomagenesis. Copyright © 2010 John Wiley & Sons, Ltd.
Towards non-invasive EEG-based arm/hand-control in users with spinal cord injury

Restoring the ability to reach and grasp can dramatically improve quality of life for people with cervical spinal cord injury (SCI). The main challenge in restoring independent reaching and grasping in patients is to develop assistive technologies with intuitive and non-invasive user interfaces. We believe that this challenge can be met by directly translating movement-related brain activity into control signals. During the last decade, we have conducted research on EEG-based brain-computer interfaces (BCIs) for the decoding of movement parameters, such as trajectories and targets. Although our findings are promising, the control is still unnatural. Therefore, we surmise that natural and intuitive control of neuroprostheses could be achieved by developing a novel control framework that incorporates detection of goal directed movement intention, movement decoding, identifying the type of grasp, error potentials detection and delivery of feedback.
Near-field characterization of guided polariton propagation and cutoff in surface plasmon waveguides

We present a series of near-field experiments characterizing cutoff for the three lowest order leaky surface plasmon modes supported by Au stripes on glass substrates. These studies demonstrate that the propagation of light along surface plasmon waveguides is mediated by a discrete number of guided polariton modes as well as a continuum of radiation modes. To distinguish the contribution of the guided modes from that of the radiation continuum, a parametric study of propagation length as a function of varying stripe width is performed. Discontinuities consistent with the loss of a guided mode are observed near cutoff widths predicted by numerical simulations, and a severe decrease in propagation length is observed below cutoff for the fundamental surface plasmon mode. Contrary to previous interpretations, experimental and numerical investigations confirm that the finite propagation lengths observed along the narrowest stripes are in good agreement with an intuitive model for the radiation continuum. Furthermore, multimode interference studies provide direct evidence for multiple guided modes and support previous findings with regard to modal cutoff.
Effects of a Single High Dose of Cisplatin on the Melanocytes of the Stria Vascularis in the Guinea Pig

The antineoplastic drug cisplatin is known to cause a reduction in endocochlear potential. The hypothesis to be tested was whether a single high dose of cisplatin affects the melanocytes by altering the expression of melanin. Pigmented guinea pigs received a bolus injection of cisplatin (8 mg/kg as a 15-second intravenous infusion). Auditory brainstem response (ABR) thresholds and morphological analysis of the hair cells and the stria vascularis were made 96 h after injection. ABR thresholds were elevated (15–40 dB) at 12–30 kHz and a significant loss of outer hair cells in the more basal regions was found. Cisplatin caused a significantly lower density of melanin in the intermediate cells in the basal region without any signs of apoptosis. Changes in melanin content were not noted in the middle or apical cochlear regions. Significant correlations were found between melanin density, ABR threshold shifts and outer hair cell loss in the region corresponding to 30 kHz. The findings reported here further support the multiple cytotoxic effect of cisplatin on the inner ear.
Optimal sampling in retrospective logistic regression via two‐stage method

Case–control sampling is popular in epidemiological research because of its cost and time saving. In a logistic regression model, with limited knowledge on the covariance matrix of the point estimator of the regression coefficients a priori, there exists no fixed sample size analysis. In this study, we propose a two‐stage sequential analysis, in which the optimal sample fraction and the required sample size to achieve a predetermined volume of a joint confidence set are estimated in an interim analysis. Additionally required observations are collected in the second stage according to the estimated optimal sample fraction. At the end of the experiment, data from these two stages are combined and analyzed for statistical inference. Simulation studies are conducted to justify the proposed two‐stage procedure and an example is presented for illustration. It is found that the proposed two‐stage procedure performs adequately in the sense that the resultant joint confidence set has a well‐controlled volume and achieves the required coverage probability. Furthermore, the optimal sample fractions among all the selected scenarios are close to one. Hence, the proposed procedure can be simplified by always considering a balance design.
More Extensive Implementation of the Chronic Care Model is Associated with Better Lipid Control in Diabetes

Objective: Chronic disease collaboratives help practices redesign care delivery. The North Carolina Improving Performance in Practice program provides coaches to guide implementation of 4 key practice changes: registries, planned care templates, protocols, and self-management support. Coaches rate progress using the Key Drivers Implementation Scales (KDIS). This study examines whether higher KDIS scores are associated with improved diabetes outcomes. Methods: We analyzed clinical and KDIS data from 42 practices. We modeled whether higher implementation scores at year 1 of participation were associated with improved diabetes measures during year 2. Improvement was defined as an increase in the proportion of patients with hemoglobin A1C values <9%, blood pressure values <130/80 mmHg, and low-density lipoprotein (LDL) levels <100 mg/dL. Results: Statistically significant improvements in the proportion of patients who met the LDL threshold were noted with higher “registry” and “protocol” KDIS scores. For hemoglobin A1C and blood pressure values, none of the odds ratios were statistically significant. Conclusions: Practices that implement key changes may achieve improved patient outcomes in LDL control among their patients with diabetes. Our data confirm the importance of registry implementation and protocol use as key elements of improving patient care. The KDIS tool is a pragmatic option for measuring practice changes that are rooted in the Chronic Care Model.
Electromagnetic Wave Propagation in Random Waveguides

We study long range propagation of electromagnetic waves in random waveguides with rectangular cross-section and perfectly conducting boundaries. The waveguide is filled with an isotropic linear dielectric material, with randomly fluctuating electric permittivity. The fluctuations are weak, but they cause significant cumulative scattering over long distances of propagation of the waves. We decompose the wave field in propagating and evanescent transverse electric and magnetic modes with random amplitudes that encode the cumulative scattering effects. They satisfy a coupled system of stochastic differential equations driven by the random fluctuations of the electric permittivity. We analyze the solution of this system with the diffusion approximation theorem, under the assumption that the fluctuations decorrelate rapidly in the range direction. The result is a detailed characterization of the transport of energy in the waveguide, the loss of coherence of the modes, and the depolarization of the waves due to cumulative scattering.
A10-cM YAC Contig Spanning GLC1A, the Primary Open-Angle Glaucoma Locus at 1q23–q25

Primary open-angle glaucoma is a complex of ocular disorders characterized by irreversible lesions of the optic nerve, open angle of the anterior chamber of the eye and elevated intraocular pressures. GLC1A, a locus involved in one form of this disease, has been mapped to an approximately 9-cM interval within 1q23–q25, between markers D1S445 and D1S416/D1S480. A 10-cM yeast artificial chromosome (YAC) contig spanning the whole region is described. This contig is based on 67 YACs, and 41 sequence tagged sites comprising 23 genetic markers, 16 YAC ends and 2 expressed sequence tags. The reagents reported in this study should be useful tools for the identification of the GLC1A gene by positional cloning.
Algoritmos Quânticos para uma Classe de Produtos Semi-diretos de Grupos

Nós apresentamos um algoritmo quântico eficiente para o problema do subgrupo oculto (PSO) sobre produto semi-direto de grupos ZN oφ Zp, onde p é um número primo ı́mpar, m,N inteiros positivos. Nós mostramos que impondo algumas restrições sobre a fatoração prima de N , o grupo ZN oφ Zp é isomorfo ao produto direto de grupos G′ = ZN ′ × (Zpr oψ Zp). A partir deste ponto nós resolvemos o PSO em G′ determinando uma solução eficiente para o PSO em cada parte do produto direto de grupos. Este algoritmo quântico é exponencialmente mais rápido do que qualquer algoritmo clássico para a mesma finalidade.
Doping Graphitic and Carbon Nanotube Structures with Boron and Nitrogen

Composite sheets and nanotubes of different morphologies containing carbon, boron, and nitrogen were grown in the electric arc discharge between graphite cathodes and amorphous boron-filled graphite anodes in a nitrogen atmosphere. Concentration profiles derived from electron energy-loss line spectra show that boron and nitrogen are correlated in a one-to-one ratio; core energy-loss fine structures reveal small differences compared to pure hexagonal boron nitride. Boron and carbon are anticorrelated, suggesting the substitution of boron and nitrogen into the carbon network. Results indicate that singlephaase CyBxNx as well as separated domains (nanosize) of boron nitride in carbon networks may exist.
Couplage de micro résonateurs. Applications aux fonctions optiques de traitement du signal. (Micro resonators coupling: applications in optical signal processing)

Nous presentons dans ce memoire de these des travaux qui portent sur l'etude de micro resonateurs a modes de galerie et en anneau couples dans le but d'applications aux fonctions optiques de traitement du signal. Dans une premiere partie nous presentons un modele matriciel pour decrire la propagation de la lumiere dans des structures a anneaux couples. L'utilisation de ce modele se resume pour des structures dont on connait les coefficients de couplage entre les guides. Dans le cas de resonateurs constitues d'un milieu qui ne presente pas d'effets non-lineaires nous avons montre que les structures a anneaux couples permettent de realiser la synthese de filtres optiques. Si les resonateurs sont le siege d'une non linearite dispersive d'ordre 3 nous avons deux cas possibles en fonction du type d'excitation. Hors resonance nous avons montre que nous pouvons obtenir potentiellement des dispositifs /N+1/ stables en utilisant un systeme forme de /N/ anneaux couples, ainsi que la tristabilite dans un seul anneau en utilisant un signal de commande. A resonance nous avons montre que l'on peut obtenir la fonction de remise en forme du signal pour des debits de 40 Gb/s. La deuxieme partie porte sur les travaux realises sur l'oscillateur optoelectronique. Dans le schema classique d'un tel oscillateur la fonction de retard optique est obtenue en utilisant une ligne a fibre optique de longueur proportionnelle au retard necessaire. Nous voulons remplacer cette ligne avec une ligne a retard a base de microresonateurs. Nous presentons des procedes de fabrication de resonateurs spheriques et diverses methodes de mesure de leurs facteurs de qualite, proportionnel au retard induit.
Paraneoplastic Neurological Syndromes and the Role of PET Imaging

Paraneoplastic neurological syndromes are immune-mediated effects of cancer that involve the nervous system and are associated with various anti-neuronal antibodies. They can be associated with several cancers such as lung, gynecologic, thymic, testicular and others, but the diagnosis of cancer often becomes a challenge, since paraneoplastic neurological syndromes usually precede the cancer presentation by months or even years. Furthermore, even when the cancer develops, the tumor size remains small and usually undetectable by conventional diagnostic tests and imaging. Positron emission tomography imaging may be an adjunct to timely diagnosis of the occult malignancy in order to employ the specific cancer treatment. Furthermore, positron emission tomography can assess the extent of the functional abnormality in the brain and monitor its response to treatment.
Could NF-kappaB and caspase-3 be markers for estimation of post-interval of human traumatic brain injury?

BACKGROUND Previous studies in a rat model showed expressions of caspase-3 (p20) and NF-kappaB (p65) in different time after TBI. We test the activation changes of caspase-3 and NF-kappaB of human specimen after traumatic brain injury (TBI) in this study to see whether they could be markers to estimate post-intervals of TBI for forensic practice. MATERIAL AND METHODS Caspase-3 (p20) and NF-kappaB (p65) immunohistochemical staining were performed on 39 TBI specimens (dead from TBI) and eight controls (dead from none TBI reasons) grouped 0, 12, 24, 48, 72, 168, 264 and 480 h. Positive cells were counted and image analysis techniques were used to determine the morphological changes in each group. RESULTS Immunohistochemical analysis showed a marked induction of caspase-3 (p20) in every injured group compared with normal controls; each positive group has it's morphological character with variant positive cell count. NF-kappaB (p65) did not showed markedly change compared with normal controls until 168 h after TBI and almost all nerve cells were stained by NF-kappaB (p65) in 264 and 480 h groups. CONCLUSION NF-kappaB (p65) could contribute to estimate delayed death cases after TBI for forensic applications. Caspase-3 (p20) estimating post-TBI intervals are dubious but could suggest TBI exists.
Enhanced magnetoresistance in layered magnetic structures with antiferromagnetic interlayer exchange.

The electrical resistivity of Fe-Cr-Fe layers with antiferromagnetic interlayer exchange increases when the magnetizations of the Fe layers are aligned antiparallel. The effect is much stronger than the usual anisotropic magnetoresistance and further increases in structures with more than two Fe layers. It can be explained in terms of spin-flip scattering of conduction electrons caused by the antiparallel alignment of the magnetization.