Miracle-dz/UniFAR-FTUs huggingface dataset:
Modeling of induction motor including the saturation effect using the finite element method

In this paper the induction motor is modeled in order to analyze the steady state and transient behavior and assess the characteristics of the electromagnetic torque and efficiency depending on the load. The finite element method is applied for solving the magnetic field equations throughout the x-y plane of the machine, taking into account the physical characteristics of the induction motor and, mainly incorporating the effect of the nonlinear characteristic of the core. This methodology will allow assessing the parameters of the machine more accurately than conventional methods to determine the parameters.
Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 *

J. Bousquet, N. Khaltaev, A. A. Cruz, J. Denburg, W. J. Fokkens, A. Togias, T. Zuberbier, C. E. Baena-Cagnani, G. W. Canonica, C. van Weel, I. Agache, N. A t-Khaled, C. Bachert, M. S. Blaiss, S. Bonini, L. -P. Boulet, P.-J. Bousquet, P. Camargos, K. -H. Carlsen, Y. Chen, A. Custovic, R. Dahl, P. Demoly, H. Douagui, S. R. Durham, R. Gerth van Wijk, O. Kalayci, M. A. Kaliner, Y. -Y. Kim, M. L. Kowalski, P. Kuna, L. T. T. Le, C. Lemiere, J. Li, R. F. Lockey, S. Mavale-Manuel , E. O. Meltzer, Y. Mohammad, J. Mullol, R. Naclerio, R. E. O Hehir, K. Ohta, S. Ouedraogo, S. Palkonen, N. Papadopoulos, G. Passalacqua, R. Pawankar, T. A. Popov, K. F. Rabe, J. Rosado-Pinto, G. K. Scadding, F. E. R. Simons, E. Toskala, E. Valovirta, P. van Cauwenberge, D. -Y. Wang, M. Wickman, B. P. Yawn, A. Yorgancioglu, O. M. Yusuf, H. Zar Review Group: I. Annesi-Maesano, E. D. Bateman, A. Ben Kheder, D. A. Boakye, J. Bouchard, P. Burney, W. W. Busse, M. Chan-Yeung, N. H. Chavannes, A. Chuchalin, W. K. Dolen, R. Emuzyte, L. Grouse, M. Humbert, C. Jackson, S. L. Johnston, P. K. Keith, J. P. Kemp, J.-M. Klossek, D. Larenas-Linnemann, B. Lipworth, J.-L. Malo, G. D. Marshall, C. Naspitz, K. Nekam, B. Niggemann, E. Nizankowska-Mogilnicka, Y. Okamoto, M. P. Orru, P. Potter, D. Price, S. W. Stoloff, O. Vandenplas, G. Viegi, D. Williams
Dual-Modality Activity-Based Probes as Molecular Imaging Agents for Vascular Inflammation

Macrophages are cellular mediators of vascular inflammation and are involved in the formation of atherosclerotic plaques. These immune cells secrete proteases such as matrix metalloproteinases and cathepsins that contribute to disease formation and progression. Here, we demonstrate that activity-based probes (ABPs) targeting cysteine cathepsins can be used in murine models of atherosclerosis to noninvasively image activated macrophage populations using both optical and PET/CT methods. The probes can also be used to topically label human carotid plaques demonstrating similar specific labeling of activated macrophage populations. Methods: Macrophage-rich carotid lesions were induced in FVB mice fed on a high-fat diet by streptozotocin injection followed by ligation of the left common carotid artery. Mice with carotid atherosclerotic plaques were injected with the optical or dual-modality probes BMV109 and BMV101, respectively, via the tail vein and noninvasively imaged by optical and small-animal PET/CT at different time points. After noninvasive imaging, the murine carotid arteries were imaged in situ and ex vivo, followed by immunofluorescence staining to confirm target labeling. Additionally, human carotid plaques were topically labeled with the probe and analyzed by both sodium dodecyl sulfate polyacrylamide gel electrophoresis and immunofluorescence staining to confirm the primary targets of the probe. Results: Quantitative analysis of the signal intensity from both optical and PET/CT imaging showed significantly higher levels of accumulation of BMV109 and BMV101 (P < 0.005 and P < 0.05, respectively) in the ligated left carotid arteries than the right carotid or healthy arteries. Immunofluorescence staining for macrophages in cross-sectional slices of the murine artery demonstrated substantial infiltration of macrophages in the neointima and adventitia of the ligated left carotid arteries compared with the right. Analysis of the human plaque tissues by sodium dodecyl sulfate polyacrylamide gel electrophoresis confirmed that the primary targets of the probe were cathepsins X, B, S, and L. Immunofluorescence labeling of the human tissue with the probe demonstrated colocalization of the probe with CD68, elastin, and cathepsin S, similar to that observed in the experimental carotid inflammation murine model. Conclusion: We demonstrate that ABPs targeting the cysteine cathepsins can be used in murine models of atherosclerosis to noninvasively image activated macrophage populations using both optical and PET/CT methods. The probes could also be used to topically label human carotid plaques demonstrating similar specific labeling of activated macrophage populations. Therefore, ABPs targeting the cysteine cathepsins are potentially valuable new reagents for rapid and noninvasive imaging of atherosclerotic disease progression and plaque vulnerability.
Football data analysis:an elaborate analysis on what possession loss causes and what causes possession loss

In football (soccer) it is important to analyse how a match is played, in order to keep improving the performance. Today the analysis is predominantly done manually. However, techniques to keep track of players during the match are emerging. These techniques provide a lot of data, which in turn can be analysed and then help the coach get more insights of the performance of the players. This thesis explores how the data already collected by the club can be analysed to see what causes and happens after possession loss. First the data is pre-processed in order to extract only the useful information. Next the critical moments are identified by looking at the features of the data. Then the data is analysed using statistical methods in order to clarify what happens to the play after possession loss and how the players react. Furthermore, multiple classification techniques and local process models are used to analyse the game before possession loss. The automatic extraction of critical moments selects almost the same moments as a specialist. When the possession of the ball is lost the pressure put on the opponent does increase, the played on area decreases, and the players move forward. The amount of pressure put on the opponent changes due to the type of moments and the opponent. Classifiers can be used to predict when the possession of the ball changes. However, the classifiers in this thesis are not much better than random. In conclusion, there are a lot of improvements which can be made in the analysis of football data. It is possible to extract critical moments and analyse what events occurs more or less frequent in certain circumstances. The moment possession of the ball changes is hard to identify. Football data analysis iii
Evidence for threshold switching in the set process of NiO-based RRAM and physical modeling for set, reset, retention and disturb prediction

This work addresses the set and reset mechanisms in NiO-based resistive-switching memory (RRAM) devices, presenting a new physics-based model for RRAM reliability and programming. We show experimental evidence that the set process is initiated by threshold switching, that is a reversible electronic transition to a high conductance state. We develop set/reset models for prediction of programming voltage and time under sweep or pulsed conditions. The speed limitations of RRAMs are then assessed by a detailed study of reset operation in the pulsed regime, showing evidence for over-reset under high-voltage, fast programming conditions (< 1 mus).
A study on Human Resource Management Processes and Practices- A Review

The most important asset for any organization is their Human Resources and they serve the organisation to achieve its goal. Management of human resources plays an extremely vital role as compared to the technology or capital and for its effective management, organization requires effective HRM practices. HRM practices refer to activities of organization directed at managing the puddle of human resources and ensuring that the resources are engaged towards the accomplishment of organizational goal. This paper has been designed to review the existing literature based on HRM Practices. The purpose of this paper is to build up an understanding of HRM Practices and to examine the unique HRM practices implemented by different organisations. After reviewing the existing literature on HRM practices, the researchers have established that the external as well as internal factors affect the HRM practices which leads to direct or indirect effect on other variables such as employee’s attitude, employee employer relations, financial performance, employee productivity etc. and ultimately contribute to overall corporate performance. On the basis of the literature reviewed, a normative skeleton has been developed that shows how HRM practices leads to overall corporate performance
Source Software ( OSS ) for Management of Library and Information Services : An Overview

Rapid advances in technology have significantly turned libraries nature from palm leaves to open source systems. Now adoption of new technologies has become a most essential factor for the libraries to stay active as an information provider. Today all most all day-to-day activities of the library are completed through the open source technology. These technologies include the digital library, integrated library systems, content management systems, OPAC, citation management, etc. Library professionals are now effectively using this software to provide innovative services to their valued users without having high budget. This paper describes the basic features of the most popular and leading open source software used in the library for different purposes. Here author also discuss about the advantages and limitations of open source software.
Mutual Funds as Venture Capitalists? Evidence from Unicorns

“Founder-friendly” venture financings and nontraditional venture investors have both flourished over the past decade. Using detailed contract data, we study open-end mutual funds investing in private venture-backed firms. We posit that conflicts between early-stage venture investors and liquidity-constrained later-stage ones influence the classic agency problems affecting entrepreneurs and investors. We find that mutual funds with more stable funding are more likely to invest in private firms and that financing rounds with mutual fund participation have stronger redemption, stronger IPO-related rights, and less board representation. These findings are consistent with our conceptual framework.
Computerization of the Patient History -Patient Answers Compared with Medical Records

Summary Computerized medical history taking, in which patients answer questions by using a terminal, is compared with the written medical record for a group of 99 patients in internal medicine. Patient complaints were analysed with respect to their frequency of occurrence for all important tracts, such as the respiratory, the gastro-intestinal and the uro-genital tracts. About 36% of over 3,200 patient answers were identical in the patient record and the written record, but a considerable percentage of complaints (56%), that were present in the patient record, were missing in the written record; the reverse was true for 4.5%. A computerized patient record appears to contain more extensive information about patient complaints, still to be interpreted by the experienced physician.
Grading of Urologic Tumors: Is It Still Useful?

The purpose of cancer grading is to predict the biologic properties of a neoplasm by evaluating the progressive increase of the structural nuclear abnormalities and the architectural arrangement of the tumor cells. These changes occur because of chromosomal aberrations, which, through an accumulation of gene mutations, endow the neoplasm with increasing degrees of aggressiveness. The main problem with cancer grading lies in the choice of criteria used for the scoring. It follows that variations bearing the greatest biological significance and those that are more reproducible by different observers should be the ones to be selected. Admittedly, the biological utility and applicability of a grading system can be decreased or even lost with the introduction of more accurate detection methods resulting in the identification of smaller and better localized tumors. This new development forces us to look for even more precise ways to evaluate the cellular alterations in the tumor, searching for increasingly subtler morphological markers of biologic behavior. The strategy of this novel approach consists in starting with the baseline provided by the classical grading systems, and look for variations in the morphologic features among the various tumor locations and the different histological subtypes.
Excess Tyrosine Restores the Morphology and Maturation of Melanosomes Affected by the Murine Slaty Mutation

Abstract The slaty (Dctslt) mutation is known to reduce the activity of dopachrome tautomerase in melanocytes and to reduce the melanin content in the skin, hairs, and eyes. The slaty gene is known to be important for maximizing melanin deposition in melanosomes. However, it was not known whether the slaty mutation affects the morphology of melanosomes. Moreover, it was unknown whether melanosome development is modulated by melanogenic factors. In this study, the characteristics of melanosomes of slaty melanocytes in serum-free primary culture were investigated in detail under the electron microscope. In slaty melanocytes, melanosome maturation was blocked at stage III, and numerous spherical melanosomes with globular depositions of pigment in addition to elliptical melanosomes were observed. L-tyrosine (Tyr), the starting material of melanin synthesis, is known to stimulate melanin synthesis. To clarify whether L-Tyr restores the reduced production of melanin, L-Tyr was added to the culture medium and tested for its melanogenic effect. L-Tyr greatly increased the number and percentage of mature stage IV melanosomes. Moreover, L-Tyr increased elliptical melanosomes, but decreased spherical melanosomes. These results suggest that the slaty mutation inhibits the development of elliptical stage IV melanosomes, and that L-Tyr restores the development of elliptical stage IV melanosomes. L-Tyr seems to restore both the morphology and maturation of melanosomes affected by the slaty mutation.
The Anatomy of the World's Largest Extinct Rodent

Phoberomys is reported to be the largest rodent that ever existed, although it has been known only from isolated teeth and fragmentary postcranial bones. An exceptionally complete skeleton of Phoberomys pattersoni was discovered in a rich locality of fossil vertebrates in the Upper Miocene of Venezuela. Reliable body mass estimates yield ∼700 kilograms, more than 10 times the mass of the largest living rodent, the capybara. With Phoberomys, Rodentia becomes one of the mammalian orders with the largest size range, second only to diprotodontian marsupials. Several postcranial features support an evolutionary relationship of Phoberomys with pakaranas from the South American rodent radiation. The associated fossil fauna is diverse and suggests that Phoberomys lived in marginal lagoons and wetlands.
Differential Effects of IL-21 during Initiation and Progression of Autoimmunity against Neuroantigen1

The cytokine IL-21 is closely related to IL-2 and IL-15, a cytokine family that uses the common γ-chain for signaling. IL-21 is expressed by activated CD4+ T cells. We examined the role of IL-21 in the autoimmune disease experimental autoimmune encephalomyelitis (EAE), an animal model for human multiple sclerosis. IL-21 administration before induction of EAE with a neuroantigen, myelin oligodendrocyte glycoprotein peptide 35-55, and adjuvant enhanced the inflammatory influx into the CNS, as well as the severity of EAE. Autoreactive T cells purified from IL-21-treated mice transferred more severe EAE than did the control encephalitogenic T cells. No such effects were observed when IL-21 was administered after EAE progressed. Additional studies demonstrated that IL-21 given before the induction of EAE boosted NK cell function, including secretion of IFN-γ. Depletion of NK cells abrogated the effect of IL-21. Therefore, IL-21, by affecting NK cells, has differential effects during the initiation and progression of autoimmune responses against neuroantigens.
Blood pressure and progression of brain atrophy: the SMART-MR Study.

IMPORTANCE Studies have shown that both high and low blood pressure (BP) may play a role in the etiology of brain atrophy. High BP in midlife has been associated with more brain atrophy later in life, whereas studies in older populations have shown a relation between low BP and more brain atrophy. Yet, prospective evidence is limited, and the relation remains unclear in patients with manifest arterial disease. OBJECTIVE To examine the associations of baseline BP and change in BP over time with progression of brain atrophy. DESIGN The Secondary Manifestations of ARTerial disease-Magnetic Resonance (SMART-MR) Study is a prospective cohort study with baseline measurements in 2001-2005 and follow-up measurements in 2006-2009. The mean follow-up time was 3.9 years. SETTING University Medical Center Utrecht, the Netherlands. PARTICIPANTS A total of 663 patients (mean [SD] age, 57 [9] years; 81% male) with coronary artery disease, cerebrovascular disease, peripheral artery disease, or abdominal aortic aneurysm were included. MAIN OUTCOMES AND MEASURES Using automated segmentation at baseline and follow-up, change in brain parenchymal fraction, cortical gray matter fraction, and ventricular fraction (%ICV) were quantified as indicators of progression of global, cortical, and subcortical brain atrophy. RESULTS Multivariable adjusted regression analysis showed that patients with lower baseline diastolic BP (DBP) or mean arterial pressure had more progression of subcortical atrophy. The mean differences in the change in ventricular fraction between low and high DBP was 0.07% (95% CI, 0.01-0.14) and between low and high mean arterial pressure was 0.05% (95% CI, 0.00-0.10). Furthermore, in patients with higher baseline BP (DBP, mean arterial pressure, or systolic BP), those with declining BP levels over time had less progression of subcortical atrophy compared with those with rising BP levels. CONCLUSIONS AND RELEVANCE In patients with manifest arterial disease, low baseline DBP was associated with more progression of subcortical atrophy, irrespective of the BP course during follow-up. Furthermore, in patients with higher baseline BP, declining BP levels over time were associated with less progression of subcortical atrophy. This could imply that BP lowering is beneficial in patients with higher BP levels, but caution should be taken with further BP lowering in patients who already have a low DBP.
What Influences Satisfaction in Purchasing High-Value Goods? An Empirical Analysis From Brazilian Real State Industry

This research examines customer trust in the salesperson and company as well as customer perception of product value and quality as factors that affect purchase satisfaction in the preconstruction real estate industry. We developed a theoretical model and tested it empirically using Structural Equation Modeling. The results suggest that trust in the real estate broker influences customer satisfaction. Furthermore, perceived product value and trust in the homebuilder influence satisfaction with the purchase whereas perceptions of product quality had no influence. Based on our findings, we discuss implications for marketing researchers and practitioners.
A Multispectral 3-D Vision System for Invertebrate Detection on Crops

Real-time detection and identification of invertebrates on crops is a necessary capability for integrated pest management, however, this challenging task has not been well-solved. Multispectral or hyperspectral machine vision systems have shown advantages for efficient and accurate detection and identification of certain invertebrate pests. However, only using spectral information has limited the capability for detection, especially for some camouflaged pests on host plants. Three-dimensional (3-D) object representations are being intensively studied for multiview object recognition and scene understanding in many fields. However, because of the lack of proper data collection methods and robust algorithms, 3-D technologies have not yet attained applications for detecting invertebrates. We have developed a multispectral 3-D vision system, which can create denser point clouds of plants and pests using the multispectral images of ultraviolet, blue, green, red, and near-infrared. An algorithm named local variance of normals was designed, which can distinguish broad leaves from relatively larger pests in noisy point clouds. The vision system could aid integrated pest management systems for pest monitoring, or could be used as a sensor of an automatic pesticide sprayer.
Dose‐Escalating Study of the Safety and Pharmacokinetics of Nelfinavir in HIV‐Exposed Neonates

Summary: The pharmacokinetics of nelfinavir (NFV) in neonates younger than 4 weeks of age was assessed. Three cohorts of HIV‐exposed neonates were enrolled in cohorts to receive 15, 30, and 45 mg of NFV/kg twice daily in combination with stavudine and didanosine for 4 weeks after birth. Trough NFV concentrations (Cmin) were measured at 1 and 7 days of age. Intensive pharmacokinetic evaluations were performed at 14 and 28 days of age. The median NFV Cmin values in the 15 mg/kg (6 patients), 30 mg/kg (5), and 45 mg/kg (11) cohorts at 1, 7, 14, and 28 days of age were 0.19, 1.21, 0.51, and 0.33; 1.02, 3.18, 0.73, and 0.55; and 0.67, 3.21, 0.70, and 0.73 mg/L, respectively. The median area under the plasma concentration‐versus‐time curve values over 12 hours in the three cohorts at 14 and 28 days of age were 14.4 and 8.7, 19.4 and 15.8, and 23.4 and 18.5 (h. mg)/L, respectively. No serious adverse events were observed. In conclusion, the systemic exposure of NFV decreased after 7 days of age, possibly because of hepatic enzyme maturation, autoinduction of NFV metabolism, and/or changes in NFV absorption. The highly variable systemic exposure observed in the study indicates that therapeutic drug monitoring seems warranted to ensure adequate NFV dosing in this population.
An Economic Policy Perspective on Online Platforms

This report provides an overview of the relevant economic research literature on platforms or multi-sided online markets. It discusses platforms from a regulatory policy angle, including potential market failures in platforms, the extent of self-regulation and possible regulatory responses through existing competition policy, consumer protection and data protection instruments. It covers selected policy issues associated with these platforms including possible sources of bias in search engines and search rankings, data protection and the use of personal data in platforms, and platform liabilities within and beyond the e-commerce directive.