Miracle-dz/UniFAR-FTUs huggingface dataset:
A MEMS Faraday Rotator for MEMS Polarization Controllers, MEMS Magneto- Optic Spatial Light Modulators and Other Enabled Technologies

Faraday rotators that employ the magneto-optic effect are ubiquitous across several optical device categories: including optical isolators, polarization controllers, and spatial light modulators. However, Faraday rotators are notoriously difficult to fabricate at small scales due to the high magnetic field strengths required to generate significant light polarization vector rotations. In this paper, we present a novel MEMS design for Faraday rotators including a tractable inductor fabrication procedure that can create significant Faraday rotations using a small sized device. Performance estimates in the form of analytical and numerical simulation results are presented along with concepts for polarization controller and spatial light modulator realization. KEYWORDS–MEMS, Faraday effect, inductor, coil, Faraday rotator, polarization controller, magneto-optic spatial light modulator, bismuth-substituted yttrium iron garnet.
An advanced scatter search algorithm for solving job shops with sequence dependent and non-anticipatory setups

In this paper we tackle the makespan minimization in the job shop scheduling problem with sequence-dependent non-anticipatory setup times. To this end, we design a scatter search algorithm which incorporates path relinking and tabu search in its core. The good performance of this algorithm relies on a new neighborhood structure proposed in this paper based on a graph model that incorporates the non-anticipatory characteristic of setup times. To define this structure, we consider all single moves, i.e., reversals of single arcs in the solution graph, and we give some conditions that establish the feasibility and the chance of improvement for the neighbors. We present the results of an experimental study across usual benchmarks to analyze our algorithm and to compare it with the state-of-the-art. In particular, our approach establishes new best solutions for all the instances.
O ENSINO DE ECONOMIA NO BRASIL

Na ultima decada, percebeu-se uma queda na procura pelo curso de Ciencias Economicas no Brasil. De um lado, a baixa procura e consequencia da falta de clareza das atividades realizadas pelo economista, frequentemente confundidas com as atribuicoes de administradores e contadores. De outro, a visao estoica acerca da Economia, tida como um tema abrangente, multidisciplinar e com volumosa carga de metodos quantitativos, acaba por afastar o interesse de muitos profissionais, receosos pela dificuldade estigmatizada. Diante desta conjuntura, a pesquisa buscou analisar as expectativas das empresas em relacao a atuacao do economista nas organizacoes, bem como o posicionamento das Instituicoes de Ensino Superior (IES) frente as necessidades do mercado de trabalho. Por meio da revisao bibliografica, estabeleceram-se as raizes e evolucao historica do ensino de Economia no Brasil e o detalhamento das atribuicoes do economista conforme a legislacao especifica. As expectativas das empresas foram apuradas por meio de uma pesquisa de levantamento (survey), cujos resultados revelaram uma participacao ativa do economista nas organizacoes, sendo especialmente reconhecidos por sua capacidade analitica e habilidade com metodos quantitativos, confirmando as hipoteses formuladas ao inicio do projeto. Os posicionamentos das IES foram levantados com base nos conteudos curriculares. Como resultado, a pesquisa acusou como o principal fator para o modesto numero de economistas profissionais contratados a falta de esclarecimento sobre suas atribuicoes, novamente corroborando com as expectativas preliminares. Consoante aos resultados da pesquisa de levantamento, que apontou como prioridade na formacao profissional do economista a analise quantitativa, a analise das grades curriculares demonstrou que as IES com maior quantidade de horas em metodos quantitativos apresentaram melhor desempenho no ENADE. Ao final, constam breves recomendacoes para ampliacao do numero de profissionais no mercado de trabalho, em congruencia com o parecer organizacional sobre os diferenciais e capacidades do economista.
Stevens–Johnson syndrome induced by mizoribine in a patient with systemic lupus erythematosus

A 32-year-old Japanese woman, who had a treatment history of systemic lupus erythematosus (SLE) with lupus nephritis World Health Organization class IV for 11 months, visited our hospital due to fever, facial erythema, and erosion of the oral cavity on November 10, 2003. Her mucosal erosion and facial skin erythema progressed over the following week, and Stevens–Johnson syndrome was diagnosed due to pathological findings of the skin. Among the administrated drugs, only mizoribine, started 6 months earlier, produced a positive reaction in the drug lym-phocyte stimulation test. Increased prednisolone and high dose intravenous γ-globulin were given successfully. Cyclosporine at 50 mg was administered to control the SLE, followed by an increase to 100 mg on January 7, 2004. She suffered from abdominal pain, blindness, and convulsion on January 9. The magnetic resonance image of her brain prompted a diagnosis of reversible posterior leukoencephalopathy syndrome. After withdrawal of cyclosporine and control of hypertension, symptoms disappeared rapidly. Cyclophosphamide pulse therapy was successfully administrated to control lupus nephritis. This is the first report describing the relationship between Stevens–Johnson syndrome and mizoribine. Although the use of mizoribine is thought to be safe, careful observation is necessary.
A short account of Knowledge Engineering

Summary Although expert systems and knowledge engineering are attracting great attention there is still confusion about what they are. Most expert systems deal with problems which are familiar to other disciplines and their distinctive character is not always recognised. This tutorial describes the origins of expert systems in Artificial Intelligence, and the technical concept of “knowledge”. The central feature is the ideal of explicitly representing knowledge as facts, rules and other symbolic structures, rather than the traditional representation as abstract numbers or algorithms. These developments yield new solutions to old problems, and ways of solving problems whcih have previously been thought to be the preserve of the human intellect.
DEL CICLO DE VIDA DEL PRODUCTO AL CICLO DE VIDA DEL CLIENTE. UNA APROXIMACIÓN HACIA UNA CONSTRUCCIÓN TEÓRICA DEL CICLO DE VIDA DEL CLIENTE

Con base en el ciclo vital de los seres vivos, la mercadotecnica ha desarrollado modelos para explicar el comportamiento o la vida de los productos en el mercado, el modelo propuesto por Levitt ha sido estudiado y aun tiene vigencia entre los estudiosos y tomadores de decisiones de mercadotecnia, el modelo del ciclo de vida del producto muestra que las fases o etapas naturales por las que transita un producto en el mercado son: introduccion, crecimiento, madurez y declinacion; aunque hay pueden haber productos que no necesariamente siguen todas estas fases. Posteriormente, han surgido propuestas diferentes sobre el modelo del ciclo de vida del cliente, y tratando de hacer una aproximacion a las etapas o fases del ciclo de vida del cliente estas son: adquisicion, conversion, crecimiento, retencion y reactivacion. La utilidad para los mercadologos al identificar las fases del ciclo de vida del cliente es que, permite disenar estrategias y tomar mejores decisiones de mercadotecnia con el fin de maximizar el valor y obtener mayor rentabilidad para la empresa a partir de satisfacer las necesidades y expectativas del cliente.Palabras clave: Modelo, ciclo de vida, producto, cliente. AbstractBased on the life cycle of living beings, the marketing has developed models to explain the behavior or life of products in the market, the model proposed by Levitt has been studied and is still valid among scholars and decision makers of marketing, the model of the life cycle of the product shows that the natural phases or stages through which a product transits in the market are: introduction, growth, maturity and decline; although there may be products that do not necessarily follow all these phases. Subsequently, different proposals have emerged about the life cycle model of the client, and trying to make an approximation to the stages or phases of the life cycle of the client these are: acquisition, conversion, growth, retention and reactivation. The usefulness for marketers to identify the phases of the life cycle of the client is that it allows designing strategies and making better marketing decisions in order to maximize value and obtain greater profitability for the company based on satisfying the needs and expectations of the client.Keywords: Model, life cycle, product, customer.
Fetal umbilical artery flow velocity waveforms and placental resistance: pathological correlation

Summary. Placental microvascular anatomy was correlated with antenatal assessment of the umbilical circulation in 106 patients to further validate the measurement of the A/B ratio (the ratio of peak systolic to least diastolic flow velocity) of the umbilical artery flow velocity time wave‐forms as an index of blood flow resistance. Three groups of patients were studied: a normal group of 38 uncomplicated pregnancies, a control group of 33 potentially ‘at risk’ pregnancies with a normal A/B ratio matched by risk factors and gestation with the third group of 35 pregnancies with a high A/B ratio. Placental arterial resistance was quantitated by counting the number of small muscular arteries (<90 μm diameter) in the tertiary stem villi in a standard microscopic field (mean 18·5 fields/placenta). The modal small arterial vessel count was shown to be significantly less in the group with a high fetal risk and a high A/B ratio (1–2 arteries/field) than in both the normal and control groups (7–8 arteries/field). The tertiary villus count did not vary between groups. Antenatal studies of umbilical artery flow velocity waveforms with Doppler ultrasound identify a specific microvascular lesion in the placenta characterized by obliteration of small muscular arteries in the tertiary stem villi.
Resource oriented dynamic service composition matchmaking

This paper presents a resource oriented requirement and service description method. Using the input and output resources of requirements and services as targets, it provides a dynamic service composition match-making problem model, gives the steps to construct feasible solutions of service composition match-making, and then converts the model into the dynamic programming model for optimization. An example is given for explanations.
Site-directed mutagenesis of beta-lactamase leading to accumulation of a catalytic intermediate.

Site-specific mutation of Glu-166 to Ala in beta-lactamase causes a millionfold reduction in catalytic activity toward both penicillin and cephalosporin substrates and results in the stoichiometric accumulation of a normally transient acyl-enzyme intermediate. Kinetic analysis indicated that substitution of Glu-166 by Ala leads to negligible effect on the acylation half of the reaction but effectively eliminates the deacylation reaction. Such differential effects on the rates of formation and breakdown of an enzyme-substrate intermediate have not been previously reported. Thus, unlike the situation for most transfer enzymes, e.g., the serine proteases, acylation and deacylation in beta-lactamase catalysis are not "mirror" images and must involve different mechanisms. The results suggest an explanation for the different catalytic activities between the beta-lactamases and the penicillin-binding proteins involved in bacterial cell-wall synthesis.
Using semantic tagging to examine the American Dream and the Chinese Dream

Abstract This paper uses Wmatrix to generate semantic tagging to compare corpora of media representations between the American Dream and the Chinese Dream. The USAS tagger is used to assign the semantic field tags to the America Dream Corpus (ADC) and the Chinese Dream Corpus (CDC). The motivation of this study is to replicate the studies using an automated and inclusive method based on semantic tagging (Potts, A. & P. Baker. 2012. Does semantic tagging identify cultural change in British and American English? International Journal of Corpus Linguistics 17(3). 295–324), and more importantly, to conduct a broad semantic categorization on both national dreams so as to uncover the cultural, social and historical similarities and/or differences. It is found that the cultural difference of the individualistic home and work association of the American Dream versus the collectivistic nation and world attributions of the Chinese Dream. The different historical stage and social-economic contexts are disclosed from the different temporal positions from time category, and the contrastive tags associated with negative representation of the American Dream and positive representation of the Chinese Dream.
Vegetation Responses to Edge Environments in Old-Growth Douglas-Fir Forests.

Forest edges created by dispersed-patch clear-cutting have become a conspicuous landscape feature in western North America, but the effects of edge on forest structure and function are still poorly understood. In this paper we describe responses of stocking density, growth, mortality, and regeneration for three conifer species from the clear-cut edge into the interior of old-growth forest patches adjacent to 10-15 yr old clearcuts in southern Washington and central Oregon. The significance of edge effects for each variable was tested through a single-factor (distance) analysis of variance (F test). Relationships between these variables and depth-of-edge influence (i.e., edge width) on old-growth forest were characterized by nonlinear regression models. Near the edge (forest-clearcut boundary line), the old-growth forest has (1) reduced stocking density, as measured by canopy cover, number of stems per hectare, and basal area; (2) increased growth rates of dominant Douglas-fir (Pseudotsuga menziesii) and western hemlock (Tsuga heterophylla), as calculated by an index of relative growth rate; (3) elevated rates of tree mortality, as measured by standing dead and down trees (snags and logs); and (4) greater numbers of Douglas-fir and western hemlock seedlings (@<100 cm tall) and saplings (101-200 cm) but fewer of Pacific silver fir (Abies amabilis). The depth-of-edge influence, when calculated as the point along the clearcut-forest gradient at which a given variable has returned to a condition representing 2/3 of the interior forest environment, ranged from 16 to 137 m for variables related to distance from the edge. The amount of a square forest patch affected by edge decreased as patch size increased and varied greatly with the depth-of-edge influence. With increasing concerns about organisms and processes that require interior forest habitat, determining the area of residual forest influenced by adjacent clearcut is critical to current and future resource management. Responses of additional biological variables must be explored and information on edge phenomena should be extended to the scale of landscapes.
When transgenes wander, should we worry?

Norman C. Ellstrand Professor of Genetics, University of California, Riverside, California It is hard to ignore the ongoing, often emotional, public discussion of the impacts of the products of crop biotechnology. At one extreme of the hype is self-rightoeus panic, and at the other is smug
Peut-on suivre la constitution d'une conscience professionnelle ou les hésitations d'un groupe de conducteurs face à un nouvel engin

Comment formalise-ton le comportement d'un nouveau vehicule et quels liens cette formalisation entretient-elle avec sa conduite ? C'est a cette question qu'ont ete confrontes les conducteurs de bus du reseau de transport en commun de Nancy lors de l'arrivee d'un engin revolutionnaire, le bus-tram produit par Bombardier. Cette communication s'appuie sur un travail d'enquete realisee entre 2000 et 2002 dans le cadre de deux expertises demandee par le Comite d'entreprise et CHSCT.
Performance Analysis of Split-Case Sorting Systems

Split-case sorting systems are used in many retail supply chains where items must be distributed in less-than-case quantities, such as orders shipped directly to customers by catalogers and e-tailers or shipments made in less-than-case quantities from a distribution center to a retail store. These systems are particularly effective in order-packing systems where the same item is needed for multiple orders. Items are inducted into a circular sorting conveyor system one unit at a time and then delivered to an order-packing bin designated for a particular customer or retail store. We develop analytical performance models that incorporate the stochastic operating conditions faced by these systems. Our model allows system designers to predict the sorting capacity for different system configurations. More importantly, we use the model to develop insight into the system design and operation.
Cbl, IRS-1, and IRS-2 Mediate Effects of Rosiglitazone on PI3K, PKC-λ, and Glucose Transport in 3T3/L1 Adipocytes.

The thiazolidenedione, rosiglitazone, increases basal and/or insulin-stimulated glucose transport in various cell types by diverse but uncertain mechanisms that may involve insulin receptor substrate (IRS)-1-dependent PI3K. Presently, in 3T3/L1 adipocytes, rosiglitazone induced sizable increases in basal glucose transport that were: dependent on PI3K, 3-phosphoinositide-dependent protein kinase-1 (PDK-1), and PKC-λ; accompanied by increases in tyrosine phosphorylation of Cbl and Cbl-dependent increases in PI3K and PKC-λ activity; but not accompanied by increases in IRS-1/2-dependent PI3K or protein kinase B activity. Additionally, rosiglitazone increased IRS-1 and IRS-2 levels, thereby enhancing insulin effects on IRS-1- and IRS-2-dependent PI3K and downstream signaling factors PKC-λ and protein kinase B. Our findings suggest that Cbl participates in mediating effects of rosiglitazone on PI3K, PDK-1, and PKC-λ and the glucose transport system and that this Cbl-dependent pathway complements the IRS-1 and I.
Investigation of the Half Bridge and Transformer Push-Pull Pulser Topologies for Ultrasonic Transducer Excitation

Comparison of two high power pulser topologies is presented. Pulser design was aimed for piezoelectric transducer excitation, yet it can also be used for electromagnetic acoustic transducer (EMAT) or capacitive micromachined ultrasonic transducers (CMUTs) excitation. Pulser can produce both single rectangular pulse and trains of rectangular arbitrary duration pulses. In order to achieve the economy of the electrical power consumption and speed both high-pulling and low-pulling elements are active switches. Energy per pulse was used to evaluate the amount of energy consumed. Two topologies were selected for evaluation: transformer output push–pull topology and half bridge output. Experimental investigation results are presented.
Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins

Alteration of the natural tropism of adenovirus (Ad) will permit gene transfer into specific cell types and thereby greatly broaden the scope of target diseases that can be treated by using Ad. We have constructed two Ad vectors which contain modifications to the Ad fiber coat protein that redirect virus binding to either alpha(v) integrin [AdZ.F(RGD)] or heparan sulfate [AdZ.F(pK7)] cellular receptors. These vectors were constructed by a novel method involving E4 rescue of an E4-deficient Ad with a transfer vector containing both the E4 region and the modified fiber gene. AdZ.F(RGD) increased gene delivery to endothelial and smooth muscle cells expressing alpha(v) integrins. Likewise, AdZ.F(pK7) increased transduction 5- to 500-fold in multiple cell types lacking high levels of Ad fiber receptor, including macrophage, endothelial, smooth muscle, fibroblast, and T cells. In addition, AdZ.F(pK7) significantly increased gene transfer in vivo to vascular smooth muscle cells of the porcine iliac artery following balloon angioplasty. These vectors may therefore be useful in gene therapy for vascular restenosis or for targeting endothelial cells in tumors. Although binding to the fiber receptor still occurs with these vectors, they demonstrate the feasibility of tissue-specific receptor targeting in cells which express low levels of Ad fiber receptor.
Charge exchange and energy dissipation of particles interacting with metal surfaces.

Theoretical and experimental results for the charge state and energy loss of low-energy He scattered off a Ni(110) surface are compared. A first-principles theory is used to analyze both the charge state and the energy loss. Charge-exchange processes are of primordial importance to explain the energy-loss spectra. Energy straggling plays an important role in the system under study.
Parental Presence during Induction of Anesthesia versus Sedative Premedication: Which Intervention Is More Effective?

Background Both midazolam and parental presence during induction of anesthesia are routinely used to treat preoperative anxiety in children. The purpose of this investigation was to determine which of these two interventions is more effective. Methods Anxiety of the child during the perioperative period was the primary end point. Secondary end points included anxiety of the parent and compliance of the child during induction. Children (n = 88) were randomly assigned to one of three groups: (1) 0.5 mg/kg oral midazolam; (2) parental presence during induction of anesthesia; or (3) control (no parental presence or premedication). Using multiple behavioral measures of anxiety, the effect of the intervention on the children and their parents was assessed. Results Observed anxiety in the holding area (T1), entrance to the operating room (T2), and introduction of the anesthesia mask (T3) differed significantly among the three groups (P = 0.032). Post hoc analysis indicated that children in the midazolam group exhibited significantly less anxiety compared with the children in the parental‐presence group or control group (P = 0.0171). Similarly, parental anxiety scores after separation were significantly less in the midazolam group compared with the parental‐presence or control groups (P = 0.048). The percentage of inductions in which compliance of the child was poor was significantly greater in the control group compared with the parental‐presence and midazolam groups (25% vs. 17% vs. 0%, P = 0.013). Conclusions Under the conditions of this study, oral midazolam is more effective than either parental presence or no intervention for managing a child's and parent's anxiety during the preoperative period.