Miracle-dz/UniFAR-FTUs huggingface dataset:
A model based linguistic of tranferring qualified personnel resource to qualified personnel capital

This paper presents a model based on linguistic value for the transform from qualified personnel resource to qualified personnel capital. It is important to transform from qualified personnel resource to qualified personnel capital for transferring the mode of economic increase in many countries. The model of fuzzy comprehensive evaluation is established to explain the method of comprehensive benefitevaluation for the transform from qualified personnel resource to qualified personnel capital. However, the model based on linguistic value is better than the fuzzy comprehensive evaluation to explain people’s habit of thought.
Circularized copies of amplifiable resistance genes from Haemophilus influenzae plasmids

Tandem repeat amplification of resistance determinants in Haemophilus influenzae plasmids is associated with the occurrence of separate circular DNA molecules. They were demonstrated to represent mono- and multimeric forms of the amplifiable segments of the plasmids which comprise the respective resistance transposons and an additional region designated as an amplification sequence. The latter region mediates the recombinational events involved in amplification. The DNA circles apparently lack the ability to replicate autonomously but most probably provide an effective means for the translocation of resistance genes from one plasmid to another.
Determinants of successful telemedicine implementations: a literature study

Telemedicine implementations often remain in the pilot phase and do not succeed in scaling-up to robust products that are used in daily practice. We conducted a qualitative literature review of 45 conference papers describing telemedicine interventions in order to identify determinants that had influenced their implementation. The identified determinants, which would influence the future implementation of telemedicine interventions, can be classified into five major categories: (1) Technology, (2) Acceptance, (3) Financing, (4) Organization and (5) Policy and Legislation. Each category contains determinants that are relevant to different stakeholders in different domains. We propose a layered implementation model in which the primary focus on individual determinants changes throughout the development life cycle of the telemedicine implementation. For success, a visionary approach is required from the multidisciplinary stakeholders, which goes beyond tackling specific issues in a particular development phase. Thus the right philosophy is: 'start small, think big'.
A preliminary analysis of mobile app user reviews

The advent of online software distribution channels like Apple Inc.'s App Store and Google Inc.'s Google Play has offered developers a single, low cost, and powerful distribution mechanism. These online stores help users discover apps as well as leave a review. Ratings and reviews add value to both the developer and potential new users by providing a crowd-sourced indicator of app quality. Hence, for developers it is important to get positive reviews and high ratings to ensure that an app has a viable future. But, what exactly do users say on these app stores? And more importantly, what is the experience that compels a user to leave either a positive or a negative rating? Our analysis of 8.7 million reviews from 17,330 apps shows that users tend to leave short, yet informative reviews, and the rating as well as the category influences the length of a review. In this preliminary study, we found that users will leave longer messages when they rate an app poorly, and the depth of feedback in certain categories is significantly higher than for other.
Inverse dispersion engineering in silicon waveguides

We present a numerical tool that searches an optimal cross section geometry of silicon-on-insulator waveguides given a target dispersion profile. The approach is a gradient-based multidimensional method whose efficiency resides on the simultaneous calculation of the propagation constant derivatives with respect to all geometrical parameters of the structure by using the waveguide mode distribution. The algorithm is compatible with regular mode solvers. As an illustrative example, using a silicon slot hybrid waveguide with 4 independent degrees of freedom, our approach finds ultra-flattened (either normal or anomalous) dispersion over 350 nm bandwidth in less than 10 iterations.
Tourism as part of national economy

There is two-way positive relation between tourism and economic development. Tourism in contemporary economies plays growing role in achieving certain macroeconomic goals, like increased employment, development of the less developed areas and positive impact on the balance of payment (export and foreign direct investments). Businesses directly and indirectly interrelated with tourism participate in the GDP much more than tourism itself, meaning that tourism has a positive effect on different areas of the national economy. Public opinion on tourism is positive one. For all of these reasons it is important to recognize the importance of tourism as the industry in Serbian economy.
2,4-Thiazolidinedione Treatment Improves the Innate Immune Response in Dairy Goats with Induced Subclinical Mastitis

Mastitis is a major disease in dairy cows resulting in significant economic losses. In vitro works suggest that ruminants peroxisome proliferator-activated receptor gamma (PPARγ) can aid in improving the response to mastitis and can control milk fat synthesis. The objectives of the present experiment were to test if treatment with the putative PPARγ agonist 2,4-thiazolidinedione (TZD) improves (1) the response to subclinical mastitis and (2) milk fat production. Lactating goats received daily injections of 8 mg/kg BW of TZD or saline for 3 weeks. After one week of TZD injection, half of the goats in each group received intramammary infusion of Strep. uberis or saline in both halves for a total of 4 groups (n = 6/group). TZD treatment did not affect milk fat but had positive effect on milk somatic cells count, blood nonesterified fatty acids, inflammatory markers, and liver function. TZD significantly increased myeloperoxidase but did not affect leukocytes phagocytosis or insulin. TZD increased adipocytes size and had minor effect on expression of PPARγ target genes in mammary epithelial cells but not in adipose tissue. Overall, TZD ameliorated the response to intramammary infection but the effect on milk fat synthesis and expression of related transcripts was less than expected.
Genetics of schizophrenia and the new millennium: progress and pitfalls.

Schizophrenia (MIM 181500) is a severe and common psychiatric disorder afflicting 1% of the world population. The disease is characterized by psychotic symptoms and by cognitive, affective, and psychosocial impairment. As a leading cause of psychiatric admissions, schizophrenia accounts for a considerable portion of health-care expenditures and is viewed as a major public health concern. Despite extensive research, our knowledge of the structural or functional pathology of schizophrenia is limited. The only etiological factor with a reasonably firm foundation is inheritance, as evidenced by family, twin, and adoption studies that point to substantial heritability (Gottesman and Shields 1982; Gottesman 1991; Kendler and Diehl 1993). In the premolecular era, attempts to discern the underlying genetic mechanism consisted of (1) segregation analysis, testing the fit of observed familial patterns to specific genetic formulations (e.g., single–major-locus, oligogenic, and multifactorial-polygenic models); (2) searching for genetic susceptibility traits, also known as “biological markers,” that segregate with the disorder in families (e.g., neurotransmitter enzymes, receptor proteins, or metabolites; attentional and electroencephalographic measures; and indices based on brain imaging); and (3) linkage studies that used classical gene markers (e.g., leukocyte antigens, blood groups, or serum proteins). However, in spite of numerous studies, the genetic underpinnings of schizophrenia remain elusive. The disorder, which is confounded by a host of factors (e.g., phenotypic diversity, etiologic heterogeneity, incomplete penetrance, unknown mode of inheritance, uncertainty about the number of loci involved and about their interactions, and the existence of nongenetic cases or phenocopies), was consigned to a complex multifactorial etiology, with no firmly established biological correlates (Baron 1986a and 1986b; Risch 1990b; Kendler and Diehl 1993). A single major locus is unlikely as a common mode of inheritance. Oligogenic or polygenic models are plausible alternatives. The advent of molecular genetics was a turning point in schizophrenia research, enabling the systematic application of both reverse genetics (studying random, anonymous DNA markers spanning the genome) and forward-genetics (testing candidate-gene polymorphisms with presumed functional relevance for the disease) (Martin 1987; Baron and Rainer 1988; Owen and Craddock 1996). In this article I review molecular genetic findings about schizophrenia, with an eye toward methodological issues and future research.
Planet Building: A Case Study of Corporate Sustainability for a Globalized World

PLANET BUILDING A CASE STUDY OF CORPORATE SUSTAINABILITY FOR A GLOBALIZED WORLD by Darci L. Arnold With the increasing complexities of a globalized 21-century world, the growing power of industry clusters makes corporations important actors in designing sustainable development strategies. This thesis presents an applied case study at CB Richard Ellis (CBRE) as the company designed and launched its award-winning Sensible Sustainability platform. The research was conducted to determine how a large multinational company could create a business case for sustainability, and the results illustrate that value exists for firms engaged in sustainability initiatives. CBRE’s initial no-cost and low-cost activities resulted in increased operational efficiencies and lower costs. Over the course of the research period, the company migrated toward its more strategic Planet Building strategy and has begun to merge its financials with an environmental and a growing social agenda that supports the Triple Bottom Line of transformative sustainability. As a result, the company is engaged with more diverse stakeholders in new markets and is realizing the benefits of increased brand reputation, improved relationships with more demanding clients, and increased market share and revenue.
EB/RP gene family encodes tubulin binding proteins

Mutations in the adenomatous polyposis coli (APC) gene are linked to the dysplastic transformation of colorectal polyps and represent an early step in the development of colorectal tumors. Ninety‐four percent of all mutations result in the expression of a truncated APC protein lacking the C‐terminal region. The C‐terminal region of the APC protein may have a tumor suppressor function as its absence appears to be linked to the development of dysplastic lesions. Recently, we discovered and characterized a protein called RP1 which binds specifically to the C‐terminal region of the APC protein. We show now that RP1 and the other known members of the EB/RP family (EB1 and RP3) also bind directly to tubulin, both in vitro and in vivo. Immunohistochemical analyses reveal a distinct staining pattern during interphase as well as an association of RP1/EB1 with mitotic microtubule structures. The previously described puncta of the APC protein at the leading edge of membrane protrusions contact microtubule fibers that contain RP1 or EB1. Int. J. Cancer 81:275–284, 1999. © 1999 Wiley‐Liss, Inc.
Existence crises of actual financial management systems Crize de existenale sistemelor actuale de management financiar

The present financial management systems reflects only partially the economic reality and they are no longer able to act as an instrument for the management. It is absurd that an economy populated by business models based on 21st century technology to use financial management systems based mainly on the same principles formalised by Luca Paciolli in 1494. Therefore, one of the causes of the current economic crisis could be the lack of coordination between the evolution of the business models and the development of new financial management models used by companies, state and investors. The present financial management systems facilitate the existence of grey or even black bookkeeping systems, tax evasion with the help of fiscal paradises, and financial shenanigans aiming to optimise, barely illegal, the financial situations.
A Review of Analysis Techniques and Data Collection Methods for Modeling Pedestrian Crossing Behaviors

A thorough literature review was performed in this study to gain an in depth understanding of current practices and existing knowledge gaps with respect to modeling pedestrian crossing behaviors and pedestrianvehicle interactions. The review of literature concentrated on a. current analysis methods and b. approaches for data collection and performance estimation. The synthesis presented in this paper aims at providing background information in support of future research efforts aiming at improving the modeling of pedestrian-vehicle interactions in multi-modal operational analyses. Keywords—Pedestrian Crossing Behavior; Data Collection; Pedestrian-Vehicle Interactions
Research situation and development prospect of D2D

LTE D2D proximity services is known to us all as D2D underlaying a LTE-advanced cellular network. In the year of 2013, D2D technology was identified by 3GPP as one of the main researching techniques, and the standardization of D2D is in hot discussion. LTE-D2D is a new technology that can support UE connected with each other directly within(or partial within) and without cellular network coverage on the licensed spectrum. It will solve the scarcity of the wireless spectrum resource to a certain extent, and increase the spectrum efficiency of the cellular system. In this article, the development, scenarios and the key technologies of D2D are introduced, and finally some application in the future is proposed.
Dopamine Transporter Is Required for In Vivo MPTP Neurotoxicity: Evidence from Mice Lacking the Transporter

Abstract: The neurotoxic effect of 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) was tested on mice lacking the dopamine (DA) transporter (DAT−/− mice). Striatal tissue DA content and glial fibrillary acidic protein (GFAP) mRNA expression were assessed as markers of MPTP neurotoxicity. MPTP (30 mg/kg, s.c., b.i.d.) produced an 87% decrease in tissue DA levels and a 29‐fold increase in the level of GFAP mRNA in the striatum of wild‐type animals 48 h after administration. Conversely, there were no significant changes in either parameter in DAT−/− mice. Heterozygotes demonstrated partial sensitivity to MPTP administration as shown by an intermediate value (48%) of tissue DA loss. Direct intrastriatal infusion of the active metabolite of MPTP, 1‐methyl‐4‐phenylpyridinium (MPP+; 10 mM), via a microdialysis probe produced a massive efflux of DA in wild‐type mice (>320‐fold). In the DAT−/− mice the same treatment produced a much smaller increase in extracellular DA (sixfold), which is likely secondary to tissue damage due to the implantation of the dialysis probe. These observations show that the DAT is a mandatory component for expression of MPTP toxicity in vivo.
Some thoughts on legitimacy theory in social and environmental accounting

Legitimacy theory has be­ come one of the most cited theories within the social and environmental accounting area. Yet there remains deep scepticism amongst many researchers that it offers any real insight into the vol­ untary disclosures of corporations. This brief paper outlines some po­ tential refinements that may ad­ dress some of these concerns. Through bringing some of the more recent developments in the man­ agement and accounting literature on legitimacy and corporations to the table, I believe that legitimacy theory does offer a powerful mechanism for understanding vol­ untary social and environmental disclosures made by corporations, and that this understanding would provide a mechanism to engage in critical public debate. The problem for legitimacy theory in contributing to our under­ standing accounting disclosure spe­ cifically, and as a theory in general, is that the term has, on occasion, been used fairly loosely. This fail­ ure to adequately specify the theory has been identified by Suchman (1995, p.572, emphasis in original), who observed that “Many researchers employ the term legitimacy, but few define it”. Hybels (1995, p.241) comments that “As the tradesmen [sic] of social science have groped to build elabo­ rate theoretical structures with which to shelter their careers and disciplines, legitimation has been a blind man’s hammer. ” I hope this paper can continue the dialogue in the social and environmental ac­ counting literature, which is helping us, better define our understanding of Legitimacy Theory.
Comparison of gene expression patterns in articular cartilage and dedifferentiated articular chondrocytes

During monolayer culture, articular chondrocytes dedifferentiate into fibroblast‐like cells. The mechanisms underlying this process are poorly understood. We sought to further characterize dedifferentiation by identifying an extended panel of genes that distinguish articular cartilage from dedifferentiated chondrocytes. Thirty‐nine candidate marker‐genes were identified from previous studies on articular‐cartilage gene‐expression. Real‐time PCR was used to evaluate the mRNA levels for these candidates in calf articular cartilage and dedifferentiated articular chondrocytes. Twenty‐two of the candidate marker genes exhibited at least a two‐fold difference in gene expression in the two cell types. Twelve of these genes had at least a ten‐fold difference in gene expression. Tenascin C (TNC), type I collagen (COL1A1), and hypoxia‐inducible factor 1 alpha (HIF1α) showed the highest relative expression levels in dedifferentiated chonodrocytes. Type II collagen (COL2A1), type XI collagen (COL11A2), and superficial zone protein (SZP) showed the highest relative expression levels in articular cartilage. In contrast to previous findings, fibromodulin mRNA, and protein levels were higher in dedifferentiated chondrocytes. Compared to smaller subsets of markers, this panel of 12 highly differentially expressed genes may more precisely distinguish articular cartilage from dedifferentiated chondrocytes. Since many of the genes up‐regulated in dedifferentiated chondrocytes are also expressed during cartilage development, dedifferentiated chondrocytes may possess features of cartilage precursor cells. © 2011 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 30:234–245, 2012
Supply Chain Management Practices Impact on the Healthcare Perceived Organizational Performance in Malaysia

The structure of the current study is based on to the prior studies on supply chain management practices and perceived organizational performance. The objective of the current study is to create a conceptual framework to investigating the link between supply chain management practices and healthcare's perceived organizational performance that indicates the mediating impact of alliance integrated network in Malaysia. Dimensions of supply chain management practices such as demand management, information and technology management capacity and resource management, customer relationship management, supplier relationship management are determined to have a positive and significant relationship with perceived organizational performance. Furthermore, alliance network have the mediation impact on the direct relationship. The proposed research framework applies to a Malaysian health care industry which has limited studies.
Institutional Investor Preferences and Executive Compensation (replaced by CentER DP 2012-004)

In this paper, we investigate the attitudes of institutional investors, such as hedge funds, insurance companies, mutual funds and pension funds, towards a key corporate governance mechanism, namely executive compensation. The purpose of this study is to document the preferences they have about both the level and structure of executive compensation. Our analysis takes a comparative approach as we ask investors to reveal their preferences both for firms in the US and in The Netherlands. Our analysis further sheds light on who should decide on executive pay, thereby contributing to the recent debate on shareholder involvement in executive pay. Finally, we examine their views on the most important and largest component of executive pay, executive stock options, and investigate what preferences they have when it comes to the design of such options.
Perioperative complications in patients undergoing open transforaminal lumbar interbody fusion as a revision surgery.

OBJECT Transforaminal lumbar interbody fusion (TLIF) has been increasingly used to treat degenerative spine disease, including that in patients in whom earlier decompressive procedures have failed. Reexploration in these cases is always challenging and is thought to pose a higher risk of complications. To the best of the authors' knowledge, there are no current studies specifically analyzing the effects of previous lumbar decompressive surgeries on the complication rates of open TLIF. METHODS The authors performed a retrospective study of surgeries performed by a single surgeon. A total of 187 consecutive patients, in whom the senior author (A.N.) had performed open TLIF between January 2007 and January 2011, met the inclusion criteria. The patients were divided into two groups (primary and revision TLIF) for the comparison of perioperative complications. RESULTS Overall, the average age of the patients was 49.7 years (range 18-80 years). Of the 187 patients, 73 patients had no history of lumbar surgery and 114 were undergoing revision surgery. Fifty-four patients (28.9%) had a documented complication intraoperatively or postoperatively. There was no difference in the rate on perioperative complications between the two groups (overall, medical, wound related, inadvertent dural tears [DTs], or neural injury). Patients who had undergone more than one previous lumbar surgery were, however, more likely to have suffered from DTs (p = 0.054) and neural injuries (p = 0.007) compared with the rest. CONCLUSIONS In the hands of an experienced surgeon, revision open TLIF does not necessarily increase the risk of perioperative complications compared with primary TLIF. Two or more previous lumbar decompressive procedures, however, increase the risk of inadvertent DTs and neural injury.