Miracle-dz/UniFAR-FTUs huggingface dataset:
Isolation of a novel protein involved in the transport of fructose by an inducible phosphoenolpyruvate fructose phosphotransferase system in Streptococcus mutans

Fructose transport in Streptococcus mutans LG-1 is mediated by at least two distinct phosphoenolpyruvate fructose phosphotransferase systems. One system is constitutive and consists of membrane components enzyme II as well as enzyme I and heat-stable protein. The other system is inducible and requires, in addition to enzyme I and heat-stable protein, a soluble substrate-specific protein for catalytic activity. This protein factor, designated IIIfru, was purified by DEAE-cellulose chromatography, hydroxylapatite chromatography, molecular sieving on Sephadex G-75, and preparative electrophoresis. The purified preparation showed only one protein band, with a molecular weight of 12,600, on sodium dodecyl sulfate-urea-polyacrylamide gel electrophoresis, on gel electrophoresis with the discontinuous buffer Tris-glycine, and after electrofocusing in gel (pI congruent to 3.7). The molecular weight of the native protein determined by gel filtration at 4 degrees C was 51,000. Immunodiffusion experiments performed with immunoglobulins prepared against the purified IIIfru from S. mutans LG-1 suggested that other S. mutans strains possessed a IIIfru. No precipitin bands, however, were detected with extracts from S. salivarius, S. sanguis, S. lactis, S. faecalis, Staphylococcus aureus, Bacillus subtilis, Lactobacillus casei, and Escherichia coli.
A 0.5mW passive telemetry IC for biomedical applications

The radiated power received by a small coil in implantable telemetry systems is less than a milliwatt. This requires a very efficient RF to DC converter, as well as the lowest possible power consumption for the biomedical sensor and data acquisition/transmisson system. This paper describes the design of a BiCMOS integrated circuit that includes a low noise amplifier, a lowpass notch filter, an A/D converter, voltage doubler/rectifier as well as a low power voltage regulator. The entire system, including the 1. 7kΩ MR bridge sensor, consumes only 520µW average power @3V.
Finding 2-Factors Closer to TSP Tours in Cubic Graphs

In this paper we are interested in algorithms for finding $2$-factors that cover certain prescribed edge-cuts in bridgeless cubic graphs. Since a Hamilton cycle is a 2-factor covering all edge-cuts, imposing the constraint of covering those edge-cuts makes the obtained $2$-factor closer to a Hamilton cycle. We present an algorithm for finding a minimum-weight $2$-factor covering all the $3$-edge cuts in weighted bridgeless cubic graphs, together with a polyhedral description of such 2-factors and that of perfect matchings intersecting all the 3-edge cuts in exactly one edge. We further give an algorithm for finding a 2-factor covering all the $3$- and $4$-edge cuts in bridgeless cubic graphs. Both of these algorithms run in ${\rm O}(n\sp{3})$ time, where $n$ is the number of vertices. As an application of the latter algorithm, we design a 6/5-approximation algorithm for finding a minimum 2-edge-connected spanning subgraph in 3-edge-connected cubic graphs, which improves upon the previous best ratio of 5/4.
Immune cells and autoantibodies in pulmonary arterial hypertension

Analyses of immunity in pulmonary arterial hypertension (PAH) support the notion that maladaptation of the immune response exists. Altered immunity is an increasingly recognized feature of PAH. Indeed, a delicate balance between immunity and tolerance exists and any disturbance may result in chronic inflammation or autoimmunity. This is suggested by infiltration of various immune cells (e.g. macrophages, T and B lymphocytes) in remodeled pulmonary vessels. In addition, several types of autoantibodies directed against antinuclear antigens, endothelial cells (ECs) and fibroblasts have been found in idiopathic and systemic sclerosis-associated PAH. These autoantibodies may play an important role in EC apoptosis and in the expression of cell adhesion molecules. This review article provides an overview of immunity pathways highlighting their potential roles in pulmonary vascular remodeling in PAH and the possibility of future targeted therapy.
Electronic Word of Mouth Communication

Word of Mouth (WoM) and electronic World of Mouth (eWoM) are similar in their motives but diverse in their reach and impact. Whereas WoM is a traditional way of storytelling between person to person, on the other hand eWoM does the same but on digital platform such as web sites, social networks, instant messages, news feeds etc. The cost involved in story telling via traditional way could be huge and audience very limited, on the other hand the electronic form of this could be very cost effective and could have wide reach across the globe. In business world, it is a well-known and established fact that customer satisfaction, trust and brand commitment could play an important role in driving WoM and thus can have far reaching consequences on a prospective customer’s attitude and behaviour towards a company's product or services.This paper summarizes some theoretical-conceptual and methodological critical aspects identified by various scholars who analysed and applied in different studies. The analysis allows to identify interesting points for future research on the topic of factors affecting eWoM communication.
Strategic Intelligence: The Cognitive Capability to Anticipate Competitor Behavior

Research summary: Pursuing sources of entrepreneurial and competitive advantage, researchers have been exploring cognition. We examine how cognitive capabilities affect competitive performance, drawing on two constructs rooted in psychology and economics. A familiar one is analytic skill, the ability to solve abstract problems. To that, we add strategic intelligence — the ability to anticipate competitors' behavior and preempt it. Using incentivized experiments, we measure the constructs in participants, then let them compete for cash in a highly competitive market. Although the market is designed to eliminate any advantages, whether from market structure or strategic resources, some profit much more than others. We trace performance differences to heterogeneity in analytic skill and strategic intelligence, and show how the two fuel superior performance, even against tough competition. Managerial summary: Why do some entrepreneurs outperform others? How can companies succeed against tough competition? Certainly, some benefit from unique resources, such as patents, and others can winnow competition, as through mergers. But some have entered highly competitive markets, lacking obvious resources, yet managed to achieve impressive success: think Under Armour, Wal‐Mart or Home Depot. Here we test how advantage can stem from managerial cognition. We measure two kinds of cognitive skill in market participants, and then let them vie for cash in intensely competitive markets. Some end up with far more profit than others. Tracing the root of high performance, we find it is predicted by a combination of analytic skills, the ability to solve abstract problems, and strategic intelligence—ability to anticipate competitors' behavior and preempt it. Copyright © 2017 John Wiley & Sons, Ltd. Resources This article has earned an Open Data badge for making publicly available the digitally‐shareable data necessary to reproduce the reported results. The data is available at http://doi.org/10.17605/OSF.IO/P49YA. Learn more about the Open Practices badges from the Center for Open Science: https://osf.io/tvyxz/wiki.
Nutritional composition of commonly consumed composite dishes from the Central Province of Cameroon

Primary objective To provide nutritional composition of 34 composite dishes commonly consumed in Cameroon, in order to enable dietary intake to be calculated from a Quantitative Food Frequency Questionnaire developed specifically for this population to determine associations between diet and diabetes. Methods and procedures A total of 197 recipes were collected for 34 composite dishes. Multiple samples of each dish were collected from a range of 2–16 households in the villages of Evadoula and in the city of Yaounde. Main outcomes and results The average nutritional composition for these composite dishes was calculated using the US Department of Agriculture National Nutrient Database. We provide the energy, macronutrient and micronutrient content of these foods. Conclusions We provide, for the first time, the macronutrient and micronutrient content of 34 commonly consumed composite dishes in the Central Province of Cameroon. Such data are essential for calculating nutrient intake and determining associations between diet and diabetes and other chronic diseases. These data may also be used for nutrition interventions aimed at modifying commonly consumed composite dishes to improve dietary intake.
Consumers' intention to use e-money mobile using the decomposed theory of planned behavior

The purpose of this study is to understand consumers’ behavior on their intention to use e-money mobile.The study of the intention to use e-money mobile is still at the early stage in payment transaction. The e-money mobile is a new product for payment transaction that look for massive, micro, and quick means for transaction. The model that integrates in this study is the Decomposed Theory of Planned Behaviour (DTPB). In particular, it is simultaneously assesses the determinants of consumers’ intention to use e-money mobile in Indonesia which examines twelve (12) variables. The variables are attitude, awareness, subjective norm, perceived behavioral control, perceived risk, perceived security, relative advantage, complexity, social-cultural influence, family, self-confidence, and resources facilitating conditions. Based on a sample of one thousand and three hundred (1300) respondents was selected using mall-intercept method with technique sampling multistage cluster sampling and systematic random sampling in Padang, Indonesia. The Partial Least Squares Method (PLS) series PLS 2.0 M3 for algorithm and bootstrap techniques and SPSS 18 was used to test the hypothesis that has been developed. Results show that all variables had significant positive influence on the intention to use e-money mobile excluded the awareness. The awareness has positive influence but not significant on the intention to use e-money mobile. This study contributes to improve the specific theory of DTPB that generally limited to e-Commerce, e-Banking, and others social networking. The findings give more information to the issuers about the characteristic consumers and add new knowledge for academics, practioners, bank, assurance companies, airline companies and the health sector.
The Effect of Exercise Training on Endothelial Function in Cardiovascular Disease in Humans

WALTHER, C. , S. GIELEN, and R. HAMBRECHT. The effect of exercise training on endothelial function in cardiovascular disease in humans. Exerc. Sport Sci. Rev., Vol. 32, No. 4, pp. 129–134, 2004. Endothelial dysfunction occurs early in atherosclerosis in response to cardiovascular risk factors. The occurrence of endothelial dysfunction is primarily the result of reduced nitric oxide (NO) bioavailabilty. It represents an independent predictor of cardiovascular events and predicts the prognosis of the patient. Therefore, endothelial function has been identified as a target for therapeutic intervention. Regular exercise training is a nonpharmacological option to improve endothelial dysfunction in patients with cardiovascular disease by increasing NO bioavailability.
Cancer-related symptoms.

Patients with cancer experience multiple symptoms including pain, dyspnea, fatigue, depression, and cognitive impairment. These symptoms impair patients' daily functioning and their quality of life. Symptoms that can be well managed are often undertreated. A major barrier to adequate symptom treatment is poor assessment. The use of simple measurement scales greatly improves the symptom assessment process, helps direct treatment choices, and provides information about the effectiveness of treatment. Recently, better methods for symptom assessment have been developed, including brief self-report tools for the assessment of multiple symptoms and interactive voice response systems for assessing symptoms at home. Symptom assessment can be linked to evidence-based or best practice guidelines to expedite optimal symptom treatment. Because patients with cancer receiving radiotherapy are seen in the clinic frequently, the radiation oncologist can play an integral role in a comprehensive approach that involves both the medical and radiotherapeutic treatment of cancer-related symptoms.
Supporting Market Transactions through XML Contracting Container

Based on a Business Media Framework (BMF), this paper proposes an architecture for secure electronic contracts, which adhere to legal requirements and can be applied for an integrated management of market transactions. We propose the use of XML, digital signatures, and Java technology for secure electronic contracting. The resulting contract container can be applied for the support of an integrated information flow through the different services of an electronic market. In addition the container holds a control logic, that supports the management of the contract negotiation and the contract settlement. The concept provided in this paper was developed in the Secure Electronic Contracts (SeCo) project of the =mcminstitute of the University of St. Gallen and the University of Zurich, Switzerland, in cooperation with several business partners.
Corporate Sustainability and Sustainable Development: Is the Difference Simply Semantics?

There are differing perceptions of the term corporate sustainability most of which stem from the general understanding of the notion of sustainable development and its dimensions. However, a review of contemporary and extant literatures show that while there are similarities between the two concepts there are, also, marked differences. The lack of clarity in understanding the concept of corporate sustainability stemming from the differing perspectives, and dimensions of sustainable development, through which practitioners learn of it may lead to an organisation’s inability to take proper steps towards its actualisation, hence the need for clarification. This report, therefore, provides some convergence of perspectives by examining various perspectives on sustainable development and corporate sustainability, offering an analysis of various conceptual definitions and in the process develops a basic model for mapping corporate sustainability. Also, it provides a consensual definition of the concept of corporate sustainability.
Innovative Entrepreneurship in the Tourism Sector : New Insights on the Role of the Development Context

Abstract This paper is an empirical study on the drivers of innovative entrepreneurship for the tourism sector, in particular the role of the development context. Using cross-country data from the Global Entrepreneurship Monitor (GEM) project and the Human Development Index (HDI) of the United Nations Development Programme, this study finds evidence that innovative entrepreneurship is negatively related to human development. Although more developed societies have more resources available and higher levels of education development, the tourism entrepreneurs have lower probability of being innovative. More developed societies are established tourism destinations, and facing such high demand, it is possible that tourism entrepreneurs have lower incentives to innovate.
Diagnostic tests of hyperventilation syndrome.

In 90 patients referred to the pulmonary function laboratory for evaluation of hyperventilation syndrome (HVS) and in whom somatic causes of the complaints had been excluded, we investigated the degree of concordance between three widely applied diagnostic methods: 1) the standardized Nijmegen questionnaire on major daily complaints; 2) the reproduction of the same symptoms during the hyperventilation provocation test (HVPT); and 3) the responses of end-tidal CO2 fraction (FETCO2) during the HVPT. In 86% of the patients a concordance was found between Nijmegen questionnaire (i.e. score of 24/64 or more) and symptom reproduction during HVPT (i.e. recognition of at least 2 major daily complaints). Based on these combined data we made a definite diagnosis of HVS in 37 patients, of non-HVS in 40 patients, and we retained only a possible HVS in 13 patients. Each of the 16 complaints in the questionnaire contributed significantly to the distinction between HVS and non-HVS patients, and a striking similarity in rank order of daily complaints and reproduced symptoms was found. The responses in FETCO, during HVPT had little additional diagnostic value. A spontaneous fall of at least 0.25% FETCO2 during the 5 min adaptation period before the HVPT, was most reliably correlated with the aforementioned diagnostic criteria of HVS: specificity 83%, sensitivity 57%, and accuracy 70%. Neither the 3 min FETCO2 ratio nor the 5 min FETCO2 ratio during recovery after the HVPT showed a good correlation with the other diagnostic criteria. The response of FETCO2 during HVPT did especially not provide additional useful diagnostic information in the 13 patients with only possible HVS.
Multiarticular manipulator and its multi degree of freedom motion by distributed thin piston-cylinder actuators

This paper presents multiarticular manipulator for endoscope. Most of endoscope and forceps employ wire-driven mechanism. We previously proposed connected piston-cylinder actuators to drive deformable body of endoscope. Connected actuators could accumulate forces of elemental actuators. Contrary, this paper presents multiarticular manipulator integrated with distributed actuators to drive individual multiarticular elements. The multiarticular manipulator employs thin piston-cylinder actuator to drive individual multiarticular element. Pneumatic actuator, especially piston-cylinder actuator is featured by its high force density and safety for medical application. We design and demonstrate thin and large force piston-cylinder actuator. Developed actuator is thin enough to be integrated into the surface of manipulator (13 mm × 8 mm × 1.8 mm). Particularly, the thin piston-cylinder actuator generates almost four times as large force (200 mN at 400 kPa) as previous our work due to good sealing by parylene deposition. Developed actuators integrated into multiarticular elements could drive multiarticular manipulation as designed.
Coderants: método de recomendación basado en la búsqueda colaborativa y las colonias de hormigas. Aplicado a la reutilización del código fuente abierto

This paper presents CodeRAnts, a new recommendation method based on a collaborative searching technique and inspired on the ant colony metaphor. This method aims to fill the gap in the current state of the matter regarding recommender systems for software reuse, for which prior works present two problems. The first is that, recommender systems based on these works cannot learn from the collaboration of programmers and second, outcomes of assessments carried out on these systems present low precision measures and recall and in some of these systems, these metrics have not been evaluated. The work presented in this paper contributes a recommendation method, which solves these problems.
Data Visualization and Network Languages Applied to Heterogeneous Data in Bioinformatics

The analysis and interpretation of relationships between biological molecules, networks and concepts is becoming a major bottleneck in systems biology. Very often the pure amount of data and their heterogeneity provides a challenge for the visualization of the data. There are a wide variety of graph representations available, which most often map the data on 2D graphs to visualize biological interactions. These methods are applicable to a wide range of problems, nevertheless many of them reach a limit in terms of user friendliness when thousands of nodes and connections have to be analyzed and visualized. In this study we are reviewing visualization tools that are currently available for visualization of biological networks mainly invented in the latest past years. We comment on the functionality, the limitations and the specific strengths of these tools, and how these tools could be further developed in the direction of data integration and information sharing.
The right to know and genetic testing

This issue of the journal contains three sets of papers clustered around three issues: organs, genetic testing and moral enhancement. Michael Hauskeller has written a guest editorial on the issue of moral enhancement ( see page 289 ) and linked to the Author Meets Critics section of the issue ( see pages 338–352 ). In what follows I will make a few remarks on the issue of genetic testing. Two sets of questions occupy the authors writing on genetic testing in this issue. The first of these surrounds the ways in which, in the context of direct to consumer testing (DTC), the autonomy of the patient/consumer is respected, enhanced or undermined. The second issue involves how we think of the value of the genetic test itself: should we care mostly about clinical utility in this context or can a notion of personal utility play a role in the justification and permissibility of genetic testing. Effy Vayena argues that if we use understand autonomy in the way that Joseph Raz has articulated it, we are in a better position to be clear about the acceptability or otherwise of direct to consumer genetic testing ( see page 310 ). She argues that it is important to consider the nature of the options that are provided in the choice and that when we do we can see that it is a mistake only to consider the extent to which these genetic results can be understood to clinically relevant. In her commentary on Vayena's paper, Eline Bunnick suggests that it is unlikely that the broader conception of the options included in the Razian account of autonomy will help in defending the claim that DTC genetic tests promote autonomy ( see page 315 ). Instead, referring to her second paper in this issue, Bunnick claims that the broader personal value of …
Capital Account Liberalisation and China's Effect on Global Capital Flows

In 1993, China announced a plan to fully liberalise its capital account by 2000. That plan was, however, disrupted by the Asian financial crisis. China’s capital account liberalisation process has resumed over the past few years, raising the question about the sequencing of capital account liberalisation. The debate gained prominence following the renminbi depreciation in August 2015 and subsequent capital outflow pressures (Figures 1 and 2). This paper provides a brief overview of China’s capital account liberalisation, evaluates the effect of a full liberalisation of the Chinese capital account and describes how China’s liberalisation process compares with the International Monetary Fund’s (IMF) institutional view.
The Complaining Customer: A Service Provider's Best Friend?

This research investigates how firms handle customers' complaints. We examine the fundamental question of how, or whether, firms respond to consumer complaints. Specifically, we examine services, as services present a unique challenge for marketers. The human element of service delivery creates many opportunities for failure. In this research we wanted to not only study complaint responses in the services industry, but also compare responses to published response rates to customer product complaints. Our examination, across a multitude of service industries, reveals response rates that are both low and slow. Our results are not encouraging. Service firms are clearly missing out on opportunities to repair problems and build relationships with their customers.