Miracle-dz/UniFAR-FTUs huggingface dataset:
Varying exposure regimes to long term chronic intermittent hypoxia exert different outcomes and morphological effects on Wistar rats at 4600 m

The aim of this study was to compare differences in morphological effects following two regimens of simulated chronic intermittent hypoxia (4600 m) during 12 months, compared to chronic hypoxia and normoxia. Male Wistar rats were randomly assigned to four groups: Chronic intermittent hypoxia (CIH) 2 × 2 (2 days hypoxia, 2 days normoxia, n = 50), CIH4 × 4 (4 days hypoxia, 4 days normoxia, n =50), chronic hypoxia (CH) (permanent, n = 28) and control (NX) (normoxia, n = 24). Hypoxia was simulated in a hypobaric chamber (428 torr). The following parameters were assessed: ventricle wall thickness, presence of congestion, edema, hemorrhage, thrombosis, necrosis, and renal casts. In general, mortality was significantly associated with heart congestion, pulmonary edema, pulmonary hemorrhage, and liver necrosis. Intermittent as well as chronic exposure produced a common pattern of manifestations in all organs, with varying severity and time of occurrence. Right ventricle hypertrophy was observed in CIH2 × 2 and CIH4 × 4 but attained lower values than in CH. Further, the coefficient of right ventricular wall thickness rose markedly dependent upon exposure duration. Renal casts and thrombosis were also shown to be the signs of hypoxic damage. Morphological effects in intermittent hypoxia resembled an intermediate severity position compared to CH and tended to occur later, indicating that a shorter regimen seemed to be less harmful.
Ultrastructural aspects of early development of the fore-limb buds in the chick and the mouse

Light microscope investigations of the early development of the fore-limb buds in chick and mouse were made to guide electron microscope studies with these tissues. At the time of maximal development of the ectodermal apical ridge there is a higher concentration of cytoplasmic RNA in the apical ridge cells than in the other cells of the limb bud. Ultrastructural investigations showed that, in the mesoblast cells at the earliest stages, profiles of endoplasmic reticulum are often found attached to the outer nuclear membrane. Some what later, discontinuities of nuclear envelope occur by which the content of the nucleus may communicate with the endoplasmic reticulum. In the cytoplasm of the mesoblast cells at these stages there were many granules similar in form and size to secretory granules of gland cells. Ribosomes are in the polysomal condition. At stages later than 20 in chick and in 11-day-old mouse embryos, the mesoblast shows the character of a syncytial tissue. Epiblast cells possess all the characters of an epithelium with well developed junctional complexes. The desmosomes form a chain consisting of units equipped with individual dense plaques, but connected by continuous bundles of fibres running parallel to the chain. The free cell membrane of the epiblastic cells, particularly at early stages, forms numerous microvilli and single cilia. In later stages during the form action of the ectodermal apical ridge, cilia have been found between the cells. This fact indicates that when the apical ridge is formed ectodermal cells migrate towards the margin of the limb bud. At these stages microvilli are also found between the apical ridge cells where they contribute to the cell-to-cell adhesion. Beginning at stage 22 in chick embryos and from the 12th day in mouse embryos there are in cells of the apical ridge numerous and extensive Golgi systems spread throughout the cytoplasm. Some what later there appear successively lysosomes, cytolysomes and extranuclear necrotic centres. All these organelles manifest acid phosphatase activity and are thoughtto initiate the involutive process in the apical ridge. Pycnosis and karyorrhexis appear as the last stage of cellular degeneration. Degenerating cells undergo phagocytosis by neighbouring epithelial cells. A basement membrane is present at all stages of development of the chick and mouse limb buds. It is an acellular continuous structure lining the internal (basal) surface of the epiblast, but in chick embryos it shows discontinuities immediately under the apical ectodermal ridge at the time of its maximum development.
Species composition, habitat, and water quality influence coral bleaching in southern Florida.

The present study examines coral bleaching along the Florida Keys reef tract (USA) dur- ing a major thermal-stress event in the summer of 2005, and during the summers of 2006 and 2007, which were mild thermal stress years. The primary objectives were to (1) examine the spatial pattern of coral bleaching and its relationship to coral community composition and habitat and (2) determine the relationship between environmental parameters and coral-bleaching prevalence (i.e. the propor- tion of colonies that bleached within each population). Over 50% of all coral species bleached along much of the reef tract in 2005. The Lower Keys supported more colonies per unit area than elsewhere and showed the highest number of bleached coral colonies; Biscayne and the Middle Keys showed the highest coral-bleaching prevalence. The most thermally sensitive corals were Porites furcata, Millepora complanata, Siderastrea radians, Porites divaricata, Agaricia agaricites, Millepora alcicor- nis, and Porites porites. The most extensive bleaching was recorded for large colonies, ≥30 cm, except in 2005 when small branching Porites colonies (<30 cm) showed higher bleaching prevalence. Shallow-water coral colonies and corals at localities with high productivity, in the form of chlorophyll a and dissolved inorganic nitrogen concentration, showed higher bleaching prevalence than both deep coral colonies and corals at localities with low productivity. By locally regulating waste-water discharge from the land, and thereby reducing local primary productivity, the severity of coral bleaching may be reduced when subjected to high regional water temperatures.
The Relationship of Food Insecurity and Quality of Life with Helicobacter Pylori Infection

1 Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. 2 Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. 3 Research Center for Health Sciences, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran. 4 Department of Epidemiology, School of Health Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Toward Brand Equity: The Effect of Brand Awareness, Perceived Quality, Brand Association, and Brand Loyalty in Boutique Bakery Company

This study aims to determine the effect of brand awareness, perceived quality, brand association, and brand loyalty to brand equity. The object of this research is BreadLife's consumers in South Jakarta. The type of research used is explanatory research with quantitative approach. The data collection technique is done by non-probability sample technique, with sample selection using accidental sampling method. Samples are 230 respondents who are BreadLife consumers in South Jakarta. Data analysis used is descriptive analysis and Path analysis. Data analysis was done by using Partial Lest Square analysis with SmartPLS 3.0 program. The results showed that: brand awareness variables negatively affect and not significant to brand equity variable; perceived quality variable has positive and insignificant effect on brand equity; brand association variable has a positive and significant impact on brand equity; brand loyalty variable has a positive and significant effect on the brand equity. With it, BreadLife must continue to maintain the quality of its products and conduct promotions. Thus, consumers get to know their products and make customers loyal. Keywords: Product Quality, Service Quality, Customer Satisfaction, Customer Loyalty. DOI: 10.7176/JMCR/67-06 Publication date: April 30 th 2020
A Statistical Analysis of Sequence Features within Genes from Neurospora crassa

Abstract Edelmann, S. E. , and Staben, C. 1994. A statistical analysis of features within genes from Neurospora crassa. Experimental Mycology 18, 70-81. We analyzed gene sequences from Neurospora crassa deposited in GenBank or EMBL for GC content, codon usage, intron prevalence, intron length, exon length, translation initiation sites, and mRNA splice sites. Protein coding regions were 59% GC, and noncoding regions were 49% GC. Codon usage was biased, primarily due to a strong preference for C in the final position of the codons. Over 80% of N. crassa protein coding genes had introns, which are typically 60 nucleotides long. Exons varied greatly in length, but were typically much longer than introns. The distribution of nucleotides surrounding translation initiation and intron splice sites was clearly nonrandom. We derived a consensus translation initiation site of CAMMATGGCT, a 5′-intron donor site of G^GTAAGTnnYCnYY, an internal branchpoint of WRCTRACMnnnnnnYY, and a 3′-acceptor site of WACAG^.
SYNONYMY OF CECODITHA (CECODITHINAE) WITH AUSTROCHTHONIUS (CHTHONIINAE) (CHELONETHI, CHTHONIIDAE)

Abstract The holotype of Cecoditha parva Mello-Leitão 1939, from Chubut Province, Argentina, is redescribed and shown to be a typical member of the genus Austrochthonius Chamberlin 1929. The monotypic genus Cecoditha Mello-Leitão 1939 is therefore a junior subjective synonym of Austrochthonius, while the subfamily Cecodithinae Chamberlin & Chamberlin 1945 (Tridenchthoniidae) is a junior subjective synonym of Chthoniinae Daday 1888 (Chthoniidae).
Acoustic energy harvesting enhanced by locally resonant metamaterials

Acoustic energy harvesting has the potential to power small-scale electronic applications and attracts wide attention. This paper presents a two-dimensional local resonant metamaterial energy harvester. The defect in the metamaterial which can induce local resonance is utilized to enhance energy harvesting. The defect mode and key parameters of the local resonant metamaterial energy harvester which can generate the maximum voltage are determined by theoretical analysis and simulations. The experiments were conducted in a hemi-anechoic room. The output voltage and transmission spectra of the local resonant metamaterial energy harvester are basically consistent with the simulations. The experimental results show that the voltage of the local resonant metamaterial energy harvester can be enhanced 950% compared with that of the bare plate energy harvester. The maximum power density of the local resonant metamaterial energy harvester is 1.24 mW cm−3. Moreover, the maximum voltage generated by the local resonant metamaterial energy harvester is about 18 times that of the bare plate energy harvester in the outdoor experiments.
Electron Microscopic Analysis of the Effects of Tea Extract on Strength Improvement of Egg White Gels

We examined the effects of several tea extracts containing certain polyphenols on the physical properties of egg white gel. The results of compression tests showed that it was possible to increase the strength of the egg white gel by treatment with various tea extracts. The image analysis of thin sections of egg white gels by transmission electron microscopy (TEM) indicated that the network filaments were larger in the modified gel than in the egg white gel. The thickening of the filaments of the network structure suggests that tea extracts improve the strength of the egg white gel.
Floral development of Myrica gale and the controversy over floral concepts

Two bracteoles form by divisions in the second layer of cells on the transversal flanks of the floral apex. Four stamens form in the male by cell divisions in the third layer of cells; one develops opposite each bracteole and two form in the median plane on either side of the floral apex. In the female bud a girdling gynoecial primordium forms by periclinal divisions in the second layer. Growth becomes localized in two or three zones in the gynoecial primordium; upward growth results in the formation of two or three stigmas. The gynoecial wall forms by intercalary growth above and below the region of bracteole attachment. The ovule develops by the resumption of growth of the floral apex. A single vascularized integument, formed at first by periclinal divisions in the protoderm, encloses the nucellus. The development and pattern of the vascular tissue is described. Four conceptual frameworks regarding the morphological nature of the flower are outlined and the data derived from this study are analyzed in r.
Proteolytic Cleavage and Activation of Protein Kinase C μ by Caspase-3 in the Apoptotic Response of Cells to 1-β-d-Arabinofuranosylcytosine and Other Genotoxic Agents*

Protein kinase C (PKC) μ is a novel member of the PKC family that differs from the other isozymes in structural and biochemical properties. The precise function of PKCμ is not known. The present studies demonstrate that PKCμ is cleaved during apoptosis induced by 1-β-d-arabinofuranosylcytosine (ara-C) and other genotoxic agents. PKCμ cleavage is blocked in cells that overexpress the anti-apoptotic Bcl-xL protein or the baculovirus p35 protein. Our results demonstrate that PKCμ is cleaved by caspase-3 at the CQND378S site. Cleavage of PKCμ is associated with release of the catalytic domain and activation of its kinase function. We also show that, unlike the cleaved fragments of PKCδ and θ, overexpression of the PKCμ catalytic domain is not lethal. Cells stably expressing the catalytic fragment of PKCμ, however, are more sensitive to apoptosis induced by genotoxic stress. In addition, expression of the caspase-resistant PKCμ mutant partially inhibits DNA damage-induced apoptosis. These findings demonstrate that PKCμ is cleaved by caspase-3 and that expression of the catalytic domain sensitizes cells to the cytotoxic effects of ara-C and other anticancer agents.
The effect of experience in psychological practice on making ethical judgements

Abstract Objective Ethical decision‐making is a core principle in the psychology profession and ethical breaches have the potential to cause harm to clients, as well as to the profession. The present study explored the influence of experience on ethical judgements for practising psychologists when compared to psychology students. Method Thirty‐two psychologists and 63 students were presented with nine ethical dilemmas and asked to select one of two potential responses, with one of the responses endorsed by two experts as meeting ethical obligations of psychologists. Participants were asked to justify their decision‐making. Results Psychologists expressed significantly higher levels of ethical judgement on two of the nine scenarios providing limited support for the hypothesis that experience enhanced ethical decision‐making. Where differences were found justifications suggested that psychologists were more likely to consider long‐term implications and communicate stronger commitment to the professional code than did students. Conclusions The findings suggest that psychologists and students largely make ethical decisions when presented with an ethical dilemma. Where differences occur these may reflect a deeper understanding of ethics and professional obligations that is developed through experience. Making ethical decision‐making a key aspect of student training and ongoing professional development for psychologists may improve ethical decision‐making.
HYBRID APPROACH FOR HUMAN FACIAL EXPRESSION DETECTION THROUGH TLBO AND PFEF

This paper introduces facial expression detection method which is based on facial’s selected feature and optimized those selected features. The study says that human face generally faced generally consist of skin color, texture shape and size of face in this paper we study skin color and texture of human face . This process consist two steps for the same. In first known as detection of expression which uses PFEF (partial feature extension function) and in second, for optimization we used TLBO algorithm is basically a population base searching technics. Also uses soft computation technics because we cannot actual and accurate for human related activity. Varieties of technic are used for the same purpose this as per use hybrid approach to get better result.
Photoreceptors and the photoperiodic response controlling flowering ofArabidopsis

Abstract At least three photoreceptors act directly or indirectly on photoperiodic flowering responses of Arabidopsis thaliana . Photosynthetic effects of growth conditions or genotype may limit the supply of sugars to the shoot apex, so causing a delay in flowering. Blue wavelengths are also important as shown by the hy4 mutant which lacks a flavoprotein and is late to flower if the available light is rich in blue wavelengths and deficient in far-red (FR). The third class of photoreceptors, the phytochromes, primarily absorb red (R) and far-red (FR) wavebands. Two of the five phytochrome genes (A and B) are most important for controlling stem elongation. However for flowering, mutants of either gene retain an end-of-day (EOD) R/FR photoreversible response. Either these two phytochromes are not essential for flowering and one or more of the other three genes is important, and/or all five genes might contribute as only low amounts of active phytochrome are required for flowering of long-day plants.
EVALUATING THE RELATIONSHIP BETWEEN PHOTOPIGMENT SYNTHESIS AND 2‐METHYLISOBORNEOL ACCUMULATION IN CYANOBACTERIA

The relationship between photopigments and the terpene‐derived secondary metabolite, 2‐methylisoborneol (MIB), was analyzed in photoacclimated cultures of Pseudanabaena articulata Skuja throughout growth, during the diel cycle, and following chemical‐induced inhibition of the isoprenoid pathway. Accumulation of MIB coincided with the accumulation of lipophilic and phycobilin pigments during the early to mid‐exponential portion of the growth cycle with the greatest accumulation of MIB during the late‐exponential phase. Cellular release of MIB occurred as culture populations entered mid‐ to late‐logarithmic phase of growth and was greatest in irradiance‐stressed cultures. The greater correspondence of MIB accumulation with photopigments was seen in cultures transferred from a 12:12 h LD photoperiod alone and the consistent relationship between MIB and photopigment accumulation under varying irradiance suggested a photopigment‐dependent regulation for MIB synthesis. However, the consistent allocation of carbon into MIB during instances of phytofluene and tetrapyrrole biosynthetic inhibition within P. articulata and Oscillatoria perornata Skuja indicated that MIB accumulation is not limited by isopreniod‐carbon availability and does not appear to serve as an “overflow” product. Rather, MIB accumulation simply appears to reflect overall carbon accumulation resulting from increased cell metabolism.
Feature Selection for Improving Failure Detection in Hard Disk Drives Using a Genetic Algorithm and Significance Scores

Hard disk drives (HDD) are used for data storage in personal computing platforms as well as commercial datacenters. An abrupt failure of these devices may result in an irreversible loss of critical data. Most HDD use self-monitoring, analysis, and reporting technology (SMART), and record different performance parameters to assess their own health. However, not all SMART attributes are effective at detecting a failing HDD. In this paper, a two-tier approach is presented to select the most effective precursors for a failing HDD. In the first tier, a genetic algorithm (GA) is used to select a subset of SMART attributes that lead to easily distinguishable and well clustered feature vectors in the selected subset. The GA finds the optimal feature subset by evaluating only combinations of SMART attributes, while ignoring their individual fitness. A second tier is proposed to filter the features selected using the GA by evaluating each feature independently, using a significance score that measures the statistical contribution of a feature towards disk failures. The resultant subset of selected SMART attributes is used to train a generative classifier, the naïve Bayes classifier. The proposed method is tested on a SMART dataset from a commercial datacenter, and the results are compared with state-of-the-art methods, indicating that the proposed method has a better failure detection rate and a reasonable false alarm rate. It uses fewer SMART attributes, which reduces the required training time for the classifier and does not require tuning any parameters or thresholds.
Characterization of an Atypical Aeromonas salmonicida Strain Causing Epizootic Ulcer Disease in Cultured Eel

A comparison of the biochemical and serological characteristics of atypical Aeromonas salmonicida strains isolated from eel (Anguilla japonica), goldfish (Carrassius auratus), and reference strains of A. salmonicida were reinvestigated.The biochemical and serological properties of causative agents of ulcer disease in eel at Tokushima and Shizuoka prefecture, and Hiroshima University in Japan were similar with isolates previously described. Several biochemical characteristics distinguished the isolates reported here from atypical A. salmonicida strains from goldfish, eel, and typical A. salmonicida.The DNA base composition (mol% guanine plus cytosine) of the isolate was similar with those of some atypical and typical A. salmonicida previously described.The thermostable antigenic structure of atypical and typical A. salmonicida were similar to the isolate reported here. The thermolabile antigenic structures showed some differences among the strains.The structure of lipopolysaccharide (LPS) from all strains demonstrated identical pattern by electrophoretic analysis.
Identification of methyl jasmonate-responsive genes in sugarcane using cDNA arrays

O acido jasmonico (JA) e seu ester metil-jasmonato (MeJA) sao moleculas sinalizadoras derivadas do acido linolenico e estao envolvidas no desenvolvimento da planta e na resposta aos estresses. MeJA regula a expressao genica ao nivel transcricional, do processamento do RNA e da traducao. Investigamos as mudancas na expressao genica em folhas de cana-de-acucar expostas ao MeJA usando arranjos de cDNA. O RNA total isolado a 0, 0,5, 1, 3, 6 e 12 horas apos o tratamento com MeJA foi utilizado para a sintese de sondas contendo a-33P-dCTP, as quais foram, posteriormente, hibridizadas em membranas de nailon contendo 1.536 clones de cDNA. Um aumento significativo na expressao genica em resposta ao MeJA foi detectado em genes que respondem a estresses e tambem em genes com funcao desconhecida, enquanto os genes que participam da fotossintese e da assimilacao de carboidrato foram reprimidos. A busca por dominios conservados em proteinas desconhecidas e a analise digital do perfil de expressao de mRNA revelaram possiveis proteinas novas relacionadas a estresses induzidas por MeJA e os tecidos onde os genes regulados por MeJA sao preferivelmente expressos.