Miracle-dz/UniFAR-FTUs huggingface dataset:
Etude numérique et expérimentale de la croissance de couches minces déposées par pulvérisation réactive.

L’objectif de ce travail est de determiner experimentalement les parametres d’entree des logiciels de simulation, puis de comparer les resultats experimentaux et numeriques pour differents metaux ainsi que pour leurs oxydes. La configuration GLAD a ete volontairement choisie pour les structures inclinees particulieres qu’elle permet.Le processus de formation de depot en phase vapeur (PVD) peut etre divise en trois etapes : l'ejection d'atomes de la cible, le transport vers le substrat et la croissance des couches minces. Chacune est simulee par un logiciel : SRIM pour l’ejection de matiere de la cible suite a l’impact avec un ion, SIMTRA pour le transport des atomes de la cible jusqu’au substrat et Simul3D pour la croissance des depots. L’evolution des proprietes des couches inclinees (angle d’inclinaison des colonnes β, epaisseur de la couche, contraintes residuelles, etc) en fonction de la position et de l’angle d’orientation du substrat est etudiee.Les resultats experimentaux et numeriques se completent mutuellement et permettent une meilleure comprehension des nombreux aspects de l’etude.
Transcriptome analysis reveals that multiple metabolic pathways operate in Zea mays roots subjected to graphene

Background: To explore the effects and molecular mechanism of graphene on the growth and development of Zea mays L. , the seeds were randomly divided into the control and experimental groups in this study, the roots of Zea mays L. seedlings were watered by different concentrations (0~100 mg/L) graphene. Results: By evaluating the root growth indices of maize, 50 mg/L graphene increased significantly the total root length, root volume, the number of root tips and root forks of maize seedlings compared with the control group. The contents of nitrogen and potassium in the soil around the roots were elevated after the treatment of 50 mg/L graphene. Then, we compared the transcriptome changes of Zea mays roots in response to 50 mg/L graphene treatment. Transcriptional factor regulation, plant hormone signal transduction, nitrogen and potassium metabolism as well as secondary metabolism in maize roots subjected to graphene showed significant up-regulated expressions, all of which might be related to mechanisms underlying graphene response. Based on qPCR validations, we proposed several candidate genes that might be responded to the graphene treatment in maize roots. Conclusion: The transcriptional profiles presented here provide a foundation for deciphering the mechanism between the graphene and maize roots interaction.
The Impact of Nipple Repair in the Treatment of  Lactating Nipple Injury

Objective To explore the effect of nipple repair in the treatment of lactating nipple injury.Methods Patients with nipple lesions admitted to the Maternal and Child Health Hospital of Haidian District from December 2015 to January 2020 were retrospective control study. The patients received nipple repair was the study group, the patients did not treated with medicine or surgery was the control group. Patients in both groups continued to be exclusively breastfeed with good sucking, The method of chi-square test was adopted by using SPSS24.0 statistical software to compare the difference of healing effect of nipple injury, pain relief rate, and recurrence rate of nipple injury.Results A total of 167 patients were enrolled, including in the 81 study group and 86 in the control group. The cure rates of the nipple injury in the study group and in the control group were 54.3% (44/81) and 26.7% (23/86) (χ2 = 13.451, P = 0.001). The complete pain relief rate was 48.1% (39/81) and 23.3% (20/86) (χ2 = 14.170, P = 0.001). The recurrence rate was 36.4% (16/44) and 34.8% (8/23) (χ2 = 0.016, P = 0.898). Conclusion For patients with no improvement in nipple damage after correction of etiology, nipple repair can improve the healing environment of nipple breakage, relieve nipple pain.
Integrated transcriptomic and proteomic analysis reveal new insights into stone cell formation in Korla pear

Background Korla fragrant pear(P•sinkiangensis Yü)is a famous local variety of Xinjiang China. One difficulty is the high stone cell content of these pears, which causes the formation of rough skins on the fruit. To elucidate the underlying mechanisms of stone cell formation, parallel analyses of the transcriptome and proteome was performed to identify important regulators and pathways involved in stone cell formation.Results Fruit samples were collected at three important time points depending on the stages of stone cell formation (20, 50 and 80 days after flowering). A total of 24268 differentially expressed genes (DEGs) and 1011 differentially accumulated proteins (DAPs) were identified from all the time points. Function analysis of the differential genes/proteins revealed that a set of candidates was associated with stone cell formation. These candidates mainly enriched in pathways involved in lignin biosynthesis, cellulose and xylan biosynthesis, S-adenosylmethionine (SAM) metabolic process, Reactive oxygen species (ROS) production, and cell death. We mined a total of 253 DEGs, and 100 DAPs, 63 of which were significantly changed at both the transcript and protein levels during fruit development.Conclusions Our findings reveal that some intriguing genes/proteins were previously unrecognized related with the sclereid formation, which provided new insights into molecular processes regulating sclereid accumulation in pear pulp.
If the Colour of Jesus Is not an Issue, why Are you so Incensed at the Suggestion that Jesus Is Black?

Questions around the colour of Jesus are always received with reservations. Yet, not much is said about the colour of the very same Jesus that has come to adorn homes and places of worship of many black Christians across the globe. This article engages in a conversation about the colour of Jesus. It does this while being aware of the challenges that appear to be particular to black communities who seem to expect their salvation from those who do not look like them. The colour of Jesus has been a central issue for Black Theology of Liberation. This is because this theological hermeneutic was never able to relate to a god that was not sympathetic to their lived experiences.
L1 Gene Molecular Variation of Human Papilloma Virus Type 16 from Cervical Cancer Patient

Background: Cervical cancer is the second most cancer in the world after breast cancer, this cancer is caused by infection of high risk Human Papillomavirus (HPV) type 16. It is often found in cervical cancer whose genome structure is composed of L1 proteins. L1 protein makes up the viral capsid that has an important role to infect the cervical epithelium. Several studies have found the differences in HPV nucleotides variants that lead to changes in amino acids that can disrupt the structure, the nature function of the virus itself, and ultimately lead to changes in biological functions including host immunological recognition. Variation of the L1 gene will also affect the effectiveness of existing vaccines. Methods: This research is a descriptive study conducted at the laboratory of microbiology at the Faculty of Medicine at Andalas Padang University from February to August 2018 which aims to look at the molecular variations of the L1 HPV type 16 gene and see phylogenic kinship. Results: This study obtained SNPs (Single Nucleotide Polymorphism) on all HPV 16 samples in the form of C / G (6240), A / G (6432), T / G (6686), C / T (6823) and insertion of nucleotide bases ACT (6901) ) and followed by GAT base deletions (6953) variations occurring along the observed sample isolate sequences.Conclusion: There are molecular variations of the L1 HPV type 16 gene which can cause different host immune responses. Phylogenic kinship of HPV type 16 isolate in Riau is close to Asian-American isolate.
Views of Cancer Patients, Families, and Providers on Initiating and Engaging in Advance Care Planning: A Qualitative Study

Background: Advance care planning (ACP) is a formal process by which patients reflect upon their goals, values and beliefs to allow them to make decisions about their future medical treatment that align with their goals and values, improving patient-centered care. Despite this, ACP is underutilized and is reported as one of the most difficult processes of oncology. Aims: To 1) explore patients’ and families’ views of ACP and what they need from their physicians during the process; 2) explore physicians’ views of ACP, including their experiences with initiating ACP and views on ACP training; and 3) identify commonalities and differences between patients’ and families’ experiences and those of the physicians who care for them. Design and setting: Qualitative descriptive study in Nova Scotia, Canada.Methods: Semi-structured interviews with advanced cancer patients and their family members (n=8) and oncologists (n=10) were conducted. Data were analyzed using constant comparative analysis, which entailed coding, categorizing, and identifying themes recurrent across the datasets. Results: Themes were identified from the patient / family and oncologist groups, four and five respectively. Themes from patients / families included: 1) positive attitudes towards ACP; 2) healthcare professionals (HCPs) lack an understanding of patients’ and families’ informational needs during the ACP process; 3) limited access to services and supports; and 4) poor communication between HCPs. Themes from oncologists included: 1) initiation of ACP discussions; 2) navigating patient-family dynamics; 3) limited formal training in ACP; 4) ACP requires a team approach; and 5) lack of coordinated systems hinders ACP. Conclusion: Stakeholders believe ACP for advanced cancer patients is important. Patients and families desire earlier and more in-depth discussion of ACP, additional services and supports, and improved communication between their HCPs. In the absence of formal training or guidance, oncologists have used clinical acumen to initiate ACP and a collaborative healthcare team approach.
Proposition of a new allosteric binding site for potential SARS-CoV-2 3CL protease inhibitors by utilizing molecular dynamics simulations and ensemble docking

Abstract The SARS-CoV-2 3CL protease (3CLpro) shows a high similarity with 3CL proteases of other beta-coronaviruses, such as SARS and MERS. It is the main enzyme involved in generating various non-structural proteins that are important for viral replication and is one of the most important proteins responsible for SARS-CoV-2 virulence. In this study, we have conducted an ensemble docking of molecules from the DrugBank database using both the crystallographic structure of the SARS-CoV-2 3CLpro, as well as five conformations obtained after performing a cluster analysis of a 300 ns molecular dynamics (MD) simulation. This procedure elucidated the inappropriateness of the active site for non-covalent inhibitors, but it has also shown that there exists an additional, more favorable, allosteric binding site, which could be a better target for non-covalent inhibitors, as it could prevent dimerization and activation of SARS-CoV-2 3CLpro. Two such examples are radotinib and nilotinib, tyrosine kinase inhibitors already in use for treatment of leukemia and which binding to the newly found allosteric binding site was also confirmed using MD simulations. Communicated by Ramaswamy H. Sarma Graphical Abstract
Where are the Students? Social and Learning Practices in Digital Settings

The aim of the study is to understand the role of social presence in digitally mediated learning processes and, consequently, to improve the design of the courses we teach at UNED. The spaces of greatest interaction between students are social networks and mobile instant messaging services, not only for social purposes but also for learning. That is why we are researching about students’ practices in those spaces while they are studying. In this paper, we present preliminary findings identifying if those social interactions happen within the online courses or in other digital spaces.
Enhanced Photocatalytic Efficiency of Microwave Synthesized Cu/ZnO Nanocomposite

The use of visible light for the Photodegradation and mineralization of the pollutant nitrobenzene was successfully achieved using microwave synthesized coupled Cu/ZnO nanocomposite as photocatalyst by applying the dispersion method. Photocatalytic efficiency of the synthesized photocatalyst was evaluated by studying different variable conditions such as amount of photocatalyst loading, pollutant (Nitrobenzene) concentration and the reusability. Optimization study revealed that 86.7% of nitrobenzene was removed by 0.25 g/L photocatalyst at nitrobenzene concentration of 20 ppm. Mineralization of the pollutant recorded using the UV-Vis spectrophotometer shows that during 2hrs of irradiation period 86.7% degradation efficiency was obtained and 76% of the total organic carbon is removed from the solution.
N‐Chlorination rate of five‐membered heterocyclic nitrogen compounds

The kinetics of N-chlorination reaction of pyrrolidine, pyrrolidone, succinimide, 5,5,-dimethyloxazolidine-2,4-dione, 5,5-dimethylhydantoin and 1-hydroximethyl-5,5-dimethylhydantoin with HOCl in aqueous solution were studied at 25 °C, constant ionic strength and under isolation conditions in a wide pH range. The set of compounds studied in this paper is characterized by having different functional groups and the same cyclic structure, consisting of a five-member ring with a nitrogen atom in the ring, which is susceptible to be chlorinated. This series of compounds covers nine pKa units, and the kinetic studies allow us to know, like, the presence of an amino, amide or imide group modify the reactivity of nitrogenous compound. Experimental data were fitted to the first-order kinetic equation. All reactions were found to be of first order in both HOCl and nitrogenous compound concentration. Kinetics studies demonstrate that some of these compounds are hydrolyzed in alkaline medium. In each case, reaction mechanism in agreement with the experimental results is proposed. The results were compared with other compounds with similar cyclic structure (2-oxazolidinone and proline). Copyright © 2016 John Wiley & Sons, Ltd.
Role of ingredients in batter systems

Science is slowly replacing intuition as batter mix manufacturers respond to the challenge of the market for coated foods. However, we know about the basic physicochemical mechanisms governing ingredient functionality in such products, compared with the many volumes that have been written about the proper selection and evaluation of ingredients forbread, cakes, cookies, and the like. Definitions of quality requirements have been developed by those in the industry in response to specific needs. This technology is expanding to become a potentially rich market for the processors both of ingredients and of end products
Systematic vs. Idiosyncratic Liquidity: Cross-section of Stock Returns

This paper decomposes firm-specific monthly-varying Amihud (2002) illiquidity measure into two components: (i) systematic illiquidity; (ii) idiosyncratic illiquidity. While there is a positive and significant relationship between systematic illiquidity and one-month-ahead stock returns, the observed relationship disappears when very small stocks are excluded. On the other hand, investors tend to underreact to idiosyncratic (il)liquidity. Hence, stocks with positive (negative) idiosyncratic liquidity generate positive (negative) subsequent returns. More specifically, high-low idiosyncratic liquidity strategy generates around 11% annualized value-weighted risk-adjusted return. Investor inattention, illiquidity, and sentiment-driven irrational investors are the main drivers of underreaction to idiosyncratic liquidity component.
Antioxidant Effects of Ocimum Gratissimum Leaf Essential Oils as a Supplement to Extender on Chilled Canine Sperm Quality

Background:Oxidative stress during chilled storage is a major problem withcanine sperm. To improve the quality of chilled canine sperm during storage, many synthetic antioxidants have been examined, but different outcomes were investigated depending on antioxidant properties. The bioactive compounds of essential oils fromOcimum gratissimumleaves are known as a natural antioxidant source. This study aimed to evaluate the antioxidant effects of essential oils from Ocimum gratissimumleavesas a supplement in extender on chilled canine sperm during 12 days of storage. Results:The results showed thatlow concentrations of Ocimum gratissimum essential oils (25, 50, and 100µg/mL) have beneficial effectson sperm quality, whereasOcimum gratissimumessential oils athigh levels (above 200µg/mL) have harmful effects. Specifically, the addition of 100µg/mL ofOcimum gratissimum essential oilsto the extender had the greatestbeneficial effect in improving the quality of chilled canine sperm, and had a significant difference in all sperm quality parameters except motility when compared to the control group (p<0.05). Conclusions:Ocimum gratissimum essential oilshave an impact on chilled canine sperm quality in a dose-dependent manner, and the best results areachieved with a maximum dose ofOcimum gratissimum essential oils of 100µg/mL.
Regional heterogeneities of health literacy in China: a population-based study

Background: Few studies have described the geographic variation in health literacy in China. This study aimed to investigate the regional heterogeneities of health literacy levels in the Chinese population to formulate targeted health literacy promotion strategies in different economic and cultural contexts.Methods: Multi-stage stratification and cluster sampling were used to select 70 study sites from 25 provinces or municipalities in China in 2017. Health literacy was measured using the National Resident Health Literacy Monitoring Questionnaire. Multiple logistic regression was used to adjust for the factors associated with the health literacy level in the overall and regional samples.Results: A total of 3,482 participants were included in the study, comprising 1,792 (51.5%) males and 1,690 (48.5%) females. Notable geographic variation was observed in health literacy levels. The proportion of respondents with adequate health literacy was 22.3% overall, 33.0% in the eastern region, 23.1% in the central region, and 17.6% in the western region. The proportion of adequate health literacy in the different provinces and municipalities ranged from 10.5%(Xinjiang) to 47.0%(Beijing). Being a female (odds ratio [OR]=1.360; 95% confidence interval [CI]: 1.153-1.605), having a high education level (OR=1.860; 95% CI: 1.671-2.070), having a high economic status (OR=1.353; 95% CI: 1.220-1.502), having a good self-rated health status (OR=1.263; 95% CI: 1.081-1.476), and having extensive community health education (OR=1.192; 95% CI: 1.034-1.374) were independently associated with adequate health literacy.Conclusions: The health literacy level of Chinese people is still low, and there are heterogeneities among different regions, between urban and rural areas, and among different social groups. Tailored health education and promotion strategies are needed for different subgroups of residents.
Performance and Genotypes of Dairy Goats in Kenya: Lessons Learnt and the Need to Move beyond Donor Introductions

: A study was conducted in three cluster regions in Kenya where the Alpine, Toggenburg and Saanen dairy goat breeds, respectively, were kept. The objective was to determine the breeds’ relative performance for use as a basis of their recommendation to farmers. Formal questionnaires were used to obtain information on farm sizes, dairy goat sources, reasons for keeping the dairy goats, goat milk production, amount of feed offered to the goats and the constraints faced. Further information on the actual milk production and live weights of the milking does was collected directly from the farms using hired recorders. Results indicated that the dairy goats were fed between 6 kg/goat/day and 17 kg/goat/day of forage. They had a low production average of 1.4 L milk/goat/day with no clear cut breed differences. Toggenburg milking does were significantly ( p < 0.05) heavier than the other breeds (48.3 vs. 38.0 and 39.0 kg for the Alpine and Saanen dairy goats, respectively). The milk production and goat live weights were below their reported potential. Feed shortage in the dry season was a major constraint. It was concluded that farmers could keep any of the three breeds. It was recommended that data on the comparative performance from the three breeds be generated to guide on farmer choices. Governments receiving donor support on agricultural endeavours should put in place the technical and policy mechanisms to support the ventures after the donor exits, and also ensure recommendations by different donors on a technical issue are consistent and complementary.
Synthesis and characterization of temperature-sensitive hydrogels

Abstract A series of fire-resistant, temperature-sensitive hydrogels were synthesized via free radical polymerization using N-isopropylacrylamide as a temperature-sensitive monomer, N,N′-methylenebisacrylamide as a cross-linker, ammonium persulfate (APS) as an initiator, and other raw materials including acrylic acid, 2-acrylamido-2-methyl propane sulfonic acid (AMPS), and attapulgite clay (APT). The structures and properties of superabsorbent hydrogels were studied using different analytical tools such as Fourier transform infrared spectroscopy, scanning electron microscopy (SEM), and thermogravimetric analysis (TGA)/differential scanning calorimetry. The effects of the monomer, cross-linker, and other reactants (AMPS and APT) on the water absorption ability of the hydrogels were analyzed; moreover, the effect of valence of metal ions was also examined. SEM images revealed the surface of the hydrogels as uneven and corrugated. The surface toughness increased with increasing APT. The addition of APT and AMPS increased the thermal resistance of the hydrogels but decreased the temperature sensitivity. Furthermore, the swelling ratio of the hydrogels decreased with the increase in salt solution concentration and valency of metal cation present in the salt solutions.