Miracle-dz/UniFAR-FTUs huggingface dataset:
Study the Variation in Biochemical Parameters of Post Colic Surgical Horses Which Treated With Chamomile Flowers

This study was conducted to determine the antioxidative effect of Matricaria chamomilla (Chamomile) flowers on the health status of post colic Surgical interference in adult horses. The experimental data were carried out eight clinically post colic surgical horses. All the horses were undergone colic surgery in different times. After eight weeks of the surgery, the horses were fed a ration supplemented with 15% Chamomile, in comparing with horses undergone colic surgery and spend eight weeks after surgery without adding any supplementation to their ration. Total antioxidant reactivity (TAS), Malondialdehyde (MDA), Uric Acid (UA) levels, activities of muscle enzymes – Aspartate Aminotransferase (AST), Creatine Kinase (CK), and parameters of fatty acid metabolism such as Triacylglycerols (TAG) and Nonsteroidal Fatty Acids (NEFA) were determined. Average values of TAS after supplementation with Chamomile rose decreased gradually and were detected at significantly higher levels (P ≤ 0.05) in the eighth week in comparison with the control. The focus of malondialdehyde, decreased significantly (P ≤ 0.05) contrasted with the unprocessed control. The activities of AST and CK varied. However, no unsettling influence was shown in muscle homeostasis. The present outcomes indicate that the total antioxidant action of the post colic surgery horses fed a diet supplemented with Chamomile was higher, and it helped stabilize the porosity of the muscle cell membranes in the post-surgical horses.
The impact of epithelial ovarian cancer diagnosis on women's life: a qualitative study.

PURPOSE OF INVESTIGATION To describe the experience of ovarian cancer patients from symptoms complained before diagnosis until the impact of ovarian cancer diagnosis perceived by women. MATERIALS AND METHODS The authors used the Psychological General Well being Index (PGWBI) and a semi-structured interview to measure the overall well being of 39 women diagnosed with ovarian cancer in the period 2005-2010 at a secondary care hospital in northern Italy. RESULTS The PGWBI showed that the majority of the women reported general stress. On the semi-structured interview, 95% of women reported having symptoms and 69% reported a stressful event prior to diagnosis. More than 50% of women reported changes concerning life course. Almost all reported that their primary concerns had to do with the surgical scar, weight gain, and hair loss. CONCLUSIONS Ovarian cancer diagnosis has a very stressful effect on the quality of life. Early assessment of psychological problems must be an integral part of the therapeutic pathway. Gynaecologists must provide clear and useful information regarding the disease itself as well as regarding correlated symptom relief.
Low Power Balun-LNA for Subsampling Architecture of Receiver

A single-ended-to-differential conversion balun-LNA is proposed in this paper for subsampling architecture of receiver. The LNA adopts the inductively degenerated common-source common-gate (cascade) structure with noise canceling technique, which can achieve high gain and low noise figure without extra components and power consumption. For the subsampling receiver of IoT narrowband application, the LNA is integrated in 65 nm CMOS. It can achieve a noise figure of 1.5dB at the 780MHz, a differential voltage gain of 30 dB and gain and phase mismatch within 0.5 dB and 5o in the range from 775MHz to 785MHz, which is adequate for most of IoT applications. The proposed LNA consumes about 1.6mA with 1.2 V voltage supply.
Automatic music genre classification based on wavelet package transform and best basis algorithm

In this paper, an improved music genre classification method is presented. The proposed method makes use of the wavelet package transform (WPT) and the best basis algorithm (BBA) to accurately classify and increase classification performance. It is well known that WPT can generate a wavelet decomposition that offers a richer signal analysis. In this paper, the music signal is first decomposed into approximation and detail coefficients using WPT with the best basis algorithm to minimize the Shannon entropy and maximize the representation of music signal. This paper uses the Top-Down search strategy with cost function to select the best basis. Then the proposed method could apply support vector machine (SVM) to build a music genre classifier using the mel-frequency cepstral coefficients (MFCC) and log energies extracted from the decomposition coefficients of WPT with the best basis algorithm. Finally one can perform music genre classification with the built music genre classifier. Experiments conducted on three different music datasets have shown that the proposed method can achieve higher classification accuracy than other music genre classification methods with the same experimental setup.
Étude et modélisation des transferts hydriques et thermiques au sein des matériaux inorganiques poreux : application aux matériaux du patrimoine bâti ancien, exemple de l'Hypogée des Dunes à Poitiers et de la crypte de l'abbatiale de Saint-Savin-sur-Gartempe

Dans le cadre de la conservation et de la rehabilitation des bâtis anciens, les materiaux utilises pour leur construction doivent etre caracterises vis-a-vis de leurs proprietes de transferts thermiques et hydriques. La premiere etape du travail de recherche a concerne la mise au point d'un capteur de conductivite thermique et de teneur en eau des materiaux inorganiques poreux (pierres, betons, enduits) constitutifs des monuments. Les methodes d’investigation doivent rester non intrusives. Dans cet objectif, la voie suivie a ete d'adapter la mesure de conductivite thermique par une methode simplifiee du fil chaud, precedemment developpee pour les fluides corrosifs, aux pierres de taille utilisees dans le bâti ancien. Afin de transferer cette technologie des fluides vers les solides, plusieurs etapes ont ete effectuees : (1) des mesures avec le fil integre, (2) des mesures de surface, (3) estimation de l'influence de la rugosite de la surface et (4) utilisation de la methode pour l'estimation de la teneur en eau des materiaux tests.La seconde etape de la recherche a consiste en deux suivis microclimatiques effectues sur deux sites historiques : l'Hypogee des Dunes et l'abbatiale de Saint-Savin-sur-Gartempe. Le travail de these a consiste a evaluer l'impact des travaux effectues sur les conditions climatiques dans l'hypogee, et a determiner l’influence des variations climatiques sur la formation d'un voile biologique dans la crypte de Saint-Savin. Pour ce faire, l'analyse correlatoire est appliquee au traitement des donnes climatiques.
Dyscalculia in the early stages of Alzheimer's disease

Objective – To study mathematical deficits in the early stages of Alzheimer's disease (AD). Methods – Sixty‐eight patients with mild AD and 242 normal controls (NC) received a standardized battery (EC 301‐R) assessing number processing and calculation abilities. AD patients also received testing for language, memory, visuo‐spatial and executive‐attentional domains. Results – Sixty‐four AD patients (94.1%) showed impaired performances on the EC 301‐R. Mathematical deficits were evident both on calculation and number processing skills. Performance on the single tasks was related to attentional‐executive resources and to impaired number representations. Heterogeneous patterns of preserved/impaired mathematical abilities were also observed in single cases. Conclusion – Dyscalculia is an early sign of AD. It should be included among the reliable clinical hallmarks for the diagnosis of AD. Identification of dyscalculic symptoms in these patients requires composite assessment procedure.
Classification of atorvastatin effect based on shape and texture features in ultrasound images

Carotid atherosclerosis is the major cause of ischemic stroke, a leading cause of mortality and disability. Many research studies have been carried out on how to quantitatively evaluate local arterial effects of potential carotid disease treatments. In this paper, the atorvastatin effect evaluation on atherosclerosis plaques are classified based on various shape and texture features extracted from ultrasound images. First, images of atherosclerotic lesions were extracted manually from ultrasound images by an expert physician. After analysis, 26 shape and 85 texture characteristics, and vessel wall volume (VWV) percent of change, were extracted and calculated from atherosclerotic lesions. Among these, to make the method convenient and exact enough, effective features and VWV percent of change, were selected for drug treatment effect evaluation by physician. Finally, a support vector machine (SVM) classifier was utilized to classify atherosclerosis plaques between atorvastatin group and placebo group. The leave-one-case-out protocol was utilized on a database of 768 carotid ultrasound images of 12 patients (5 subjects of placebo group and 7 subjects of atorvastatin group) for evaluation. The classification results showed overall accuracy 91.67%, sensitivity 95.56%, specificity 86.16%; positive predictive value 90.72%, negative predictive value 93.20%, Matthew’s correlation coefficient 82.81%, Youden’s index 81.72%. And the receiver operating characteristic (ROC) curve in our test also performed well. The experimental results also demonstrate that classification using the combined features has higher accuracy than that only using shape/texture feature or VWV percent of change. The proposed method can be used for the statins effect evaluation, especially when patients are treated with drugs, and further be developed as a beneficial tool for facilitating a physician’s diagnosis of the atherosclerosis.
Studies on Unprocessed and Acid-Treated Arabinogalactan from Larch as an Inhibitor of Glycan Binding of a Plant Toxin and Biomedically Relevant Human Lectins

Abstract The increasing evidence for the physiological significance of glycan-protein (lectin) interactions prompts considerations for respective bioactivity of plant polysaccharides. Arabinogalactan from larch, a polysaccharide with a β1,3-linked galactose core and branches at the 6′-hydroxyl, was thus tested, together with two processed forms treated either with oxalic or trifluoroacetic acid. Hydrolysis by acid reduced the arabinose contents without backbone degradation. The three preparations were tested as an inhibitor of lectin binding in solid-phase and cell-based assays, using the toxin from Viscum album and a panel of seven human lectins (six galectins and a C-type lectin). Increasing potency correlating with the molecular contents of galactose was seen for the plant toxin. In general, relatively weak or no inhibitory capacity was detected for the three preparations, when binding of the human galectins and avian orthologues used as controls was measured. Acid-treated polysaccharides also weakly interfered with binding of the galactose-specific C-type lectin of human macrophages. Larch arabinogalactan, tested as a model, will thus most likely not impair (ga)lectin functionality physiologically.
Secure Hashing Algorithm and Advance Encryption Algorithm in Cloud Computing

Cloud computing is one of the most sharp and important movement in various computing technologies. It provides flexibility to users, cost effectiveness, location independence, easy maintenance, enables multitenancy, drastic performance improvements, and increased productivity. On the other hand, there are also major issues like security. Being a common server, security for a cloud is a major issue; it is important to provide security to protect user’s private data, and it is especially important in ecommerce and social networks. In this paper, encryption algorithms such as Advanced Encryption Standard algorithms, their vulnerabilities, risk of attacks, optimal time and complexity management and comparison with other algorithms based on software implementation is proposed. Encryption techniques to improve the performance of AES algorithms and to reduce risk management are given. Secure Hash Algorithms, their vulnerabilities, software implementations, risk of attacks and comparison with other hashing algorithms as well as the advantages and disadvantages between hashing techniques and encryption are given. Keywords—Cloud computing, encryption algorithm, secure hashing algorithm, brute force attack, birthday attack, plaintext attack, man-in-the-middle attack.
Theoretical influence of female mating status and remating propensity on male sperm allocation patterns

Theoretical models predict that males should allocate more sperm in matings where the immediate risk of sperm competition is high. It has therefore often been argued that males should invest less sperm in matings with virgin females compared with matings with already mated females. However, with relatively polyandrous females, high sperm competition risk will covary with high sperm competition intensity leading to more unpredictable conditions, as high competition intensity should favour smaller ejaculates. With the use of a genetic algorithm, we found that males should allocate more sperm in matings with virgin females when female mating frequency is relatively high, whereas low remating rates will select for higher effort in matings with nonvirgin females. At higher remating rates, first male sperm precedence favours larger ejaculates in matings with virgin females and second male precedence favours the reverse. These results shed some light on several findings that have been difficult to explain adaptively by the hitherto developed theory on sperm allocation.
Definition of post‐thrombotic syndrome of the leg for use in clinical investigations: a recommendation for standardization

Summary. The post‐thrombotic syndrome (PTS) is increasingly recognized to be a common and important complication of deep venous thrombosis (DVT). Because there is no ‘gold standard’ objective test to establish its presence, PTS is diagnosed primarily on the basis of the presence of typical symptoms and clinical signs in a limb that was affected by DVT. As a wide variety of definitions of PTS have been used by researchers, it is difficult to compare data across studies and to formally combine data in meta‐analyses. In a step towards standardization of the measurement of PTS in clinical studies, available scales and evidence to support their utility to diagnose PTS and to classify its severity were reviewed and discussed at the Control of Anticoagulation Subcommittee of the International Society on Thrombosis and Haemostasis (Vienna, July 2008).
Paralympic Legacy - learning from the Sydney 2000 to prepare for Tokyo 2020

This paper is based on an invited seminar to the Nippon Foundation Paralympic Research Group delivered in Tokyo August 2015 that was asked to review the Sydney 2000 Paralympic games legacy outcomes as a way of providing reflective learnings for the Tokyo 2020 Paralympic games. Over the last decade a great deal of work has examined major sport event legacies and event leverage. Much of this work has involved Olympic studies whereas the Paralympic games have been largely overlooked. The Paralympic Games are the second largest multi-sport event after the Olympic Games. Since Sydney 2000 there has been an 'operational partnership' where bid cities are required to host both Games. Yet, few studies have evaluated the outcomes, legacies and event leverage that Paralympic games have generated. This paper addresses this absence by presenting legacy frameworks and examining a review of Paralympic legacy research from the Sydney 2000 Paralympics. The seminar is timely in that it has been 50 years since the Tokyo 1964 Paralympics and Tokyo will be again hosting the Paralympics in 2020. The paper presents a background understanding of legacy and legacy frameworks before discussing the research design. The findings are presented using Preuss (2007) cube conceptualisations of legacy that incorporates the dimensions: planned/unplanned; tangible/intangible; and positive/negative. There are four suggested learnings from Sydney 2000 that may prepare Tokyo 2020 Paralympic games to more strategically address legacy. They are: fostering a relationship with the disability community; developing a Research agenda; educating the population about Paralympic sport; and preparing a culturally appropriate campaign to recruit volunteers. Paralympic Legacy: from Sydney 2000 to Tokyo 202
Efficacy of chlorine and heat treatment in killing Salmonella stanley inoculated onto alfalfa seeds and growth and survival of the pathogen during sprouting and storage

The efficacy of chlorine and hot water treatments in killing Salmonella stanley inoculated onto alfalfa seeds was determined. Treatment of seeds containing 10(2) to 10(3) CFU/g in 100-micrograms/ml active chlorine solution for 5 or 10 min caused a significant (P < or = 0.05) reduction in population, and treatment in 290-micrograms/ml chlorine solution resulted in a significant reduction compared with treatment in 100 micrograms of chlorine per ml. However, concentrations of chlorine of up to 1,010 micrograms/ml failed to result in further significant reductions. Treatment of seeds containing 10(1) to 10(2) CFU of S. stanley per g for 5 min in a solution containing 2,040 micrograms of chlorine per ml reduced the population to undetectable levels (< 1 CFU/g). Treatment of seeds in water for 5 or 10 min at 54 degrees C caused a significant reduction in the S. stanley population, and treatment at > or = 57 degrees C reduced populations to < or = 1 CFU/g. However, treatment at > or = 54 degrees C for 10 min caused a substantial reduction in viability of the seeds. Treatment at 57 or 60 degrees C for 5 min appears to be effective in killing S. stanley without substantially decreasing germinability of seeds. Storage of seeds for 8 to 9 weeks at 8 and 21 degrees C resulted in reductions in populations of S. stanley of about 1 log10 and 2 log10 CFU/g, respectively. The behavior of S. stanley on seeds during soaking germination, sprouting, and refrigerated storage of sprouts was determined. An initial population of 3.29 log10 CFU/g increased slightly during 6 h of soaking, by about 10(3) CFU/g during a 24-h germination period, and by an additional 10 CFU/g during a 72-h sprouting stage. A population of 10(7) CFU/g of mature alfalfa sprouts was detected throughout a subsequent 10-day storage period at 5 degrees C. These studies indicate that while populations of S. stanley can be greatly reduced, elimination of this organism from alfalfa seeds may not be reliably achieved with traditional disinfection procedures. If S. stanley is present on seeds at the initiation of the sprout production process, populations exceeding 10(7) CFU/g can develop and survive on mature sprouts exposed to handling practices used in commercial production and marketing.
The genetic basis of diffuse large B-cell lymphoma

Purpose of reviewDiffuse large B-cell lymphoma (DLBCL) is an aggressive disease featuring heterogeneous genetic, phenotypic, and clinical characteristics. Understanding the basis for this heterogeneity represents a critical step toward further progress in the management of this disease, which remains a clinical challenge in approximately one-third of patients. This review summarizes current knowledge about the molecular pathogenesis of DLBCL, and describes how recent advances in the genomic characterization of this cancer have provided new insights into its biology, revealing several potential targets for improved diagnosis and therapy. Recent findingsIn the past few years, the development of high-resolution technologies has provided significant help in identifying genetic lesions and/or disrupted signaling pathways that are required for DLBCL initiation and progression. These studies uncovered the involvement of cellular programs that had not been previously appreciated, including histone/chromatin remodeling and immune recognition. Alterations in these pathways could favor epigenetic reprogramming and escape from cellular immunity. SummaryThe identification of genetic alterations that contribute to the malignant transformation of a B cell into a DLBCL is helping to better understand the biology of this disease and to identify critical nodes driving tumor progression or resistance to therapy. The rapid pace at which these discoveries are taking place is poised to have significant impact for patient stratification based on molecular predictors and for the development of rational targeted therapies.
Natural history of Bell's palsy.

The aim of this Copenhagen facial nerve study is to explain the spontaneous course of the idiopathic facial nerve palsy without any kind of treatment. Today Bell’s palsy is the accepted term for specifying an acute monosymptomatic peripheral facial palsy of unknown etiology. Acute unilateral, and idiopathic without involvement of other peripheral nerves are specific requirements for the diagnosis.
Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia

Abnormal replication timing has been observed in cancer but no study has comprehensively evaluated this misregulation. We generated genome-wide replication-timing profiles for pediatric leukemias from 17 patients and three cell lines, as well as normal B and T cells. Nonleukemic EBV-transformed lymphoblastoid cell lines displayed highly stable replication-timing profiles that were more similar to normal T cells than to leukemias. Leukemias were more similar to each other than to B and T cells but were considerably more heterogeneous than nonleukemic controls. Some differences were patient specific, while others were found in all leukemic samples, potentially representing early epigenetic events. Differences encompassed large segments of chromosomes and included genes implicated in other types of cancer. Remarkably, differences that distinguished leukemias aligned in register to the boundaries of developmentally regulated replication-timing domains that distinguish normal cell types. Most changes did not coincide with copy-number variation or translocations. However, many of the changes that were associated with translocations in some leukemias were also shared between all leukemic samples independent of the genetic lesion, suggesting that they precede and possibly predispose chromosomes to the translocation. Altogether, our results identify sites of abnormal developmental control of DNA replication in cancer that reveal the significance of replication-timing boundaries to chromosome structure and function and support the replication domain model of replication-timing regulation. They also open new avenues of investigation into the chromosomal basis of cancer and provide a potential novel source of epigenetic cancer biomarkers.