Miracle-dz/UniFAR-FTUs huggingface dataset:
Safety Strategy for Human–Robot Collaboration: Design and Development in Cellular Manufacturing

Our research aims to design and develop a safety strategy for a human–robot collaboration system. Although robotic assistance in a cellular manufacturing system is promising, safety is the uppermost consideration before it can be materialized. Five main safety designs are developed in this work. (i) Safe working areas for humans and robots. (ii) To control the behavior of the robot based on the collaboration requirements, light curtains defined safe collaborative working zones. (iii) Additionally, the robot system was developed using safe mechanical design and Dual Check Safety control strategies in terms of robot speed and travel area to minimize collaboration risks. (iv) A vision system using IP cameras was developed to monitor operator safety conditions by measuring the body posture and position of the operator. (v) The operation control system coordinated the collaborative flow between the operator and robot system. Apart from these developments, risk assessments were conducted to evaluate the safety design of the system, and a mental safety study was performed to investigate robot motion speed and working distance on the operator's physiological effects. Our findings demonstrate the feasibility of the prototype system to safely perform assembly operations.
Cellular and molecular characterization of oxidative stress in olfactory epithelium of Harlequin mutant mouse

Oxidative stress in the olfactory system is a major factor associated with age‐related olfactory impairment, although the mechanisms by which this occurs are not completely understood. The Harlequin mutant mouse (Hq/Y), which carries an X‐linked recessive mutation in the Aifm1 gene, is a model of progressive oxidative stress–induced neurodegeneration in the cerebellum and retina. To determine whether the Hq/Y mutant mouse is a suitable model of oxidative stress–associated olfactory aging, we investigated cellular and molecular changes in the olfactory epithelium (OE) and olfactory bulb (OB) of 6‐month‐old male Hq/Y mice compared to those in sex‐matched littermate controls (+/Y) and in age‐ and sex‐matched C57BL/6 mice. Immunoreactivity for apoptosis‐inducing factor, the protein product of Aifm1, was localized in mature olfactory sensory neurons (mOSNs) in +/Y mice but was rarely detected in Hq/Y mice. Hq/Y mice also exhibited increased lipofuscin autofluorescence and increased immunoreactivity for an oxidative DNA/RNA damage marker in mOSNs and in mitral/tufted cells in the OB and an increased number of cleaved caspase‐3 immunoreactive apoptotic cells in the OE. Microarray analysis demonstrated that Aifm1 expression was down‐regulated by 80% in the OE of Hq/Y mice compared to that in +/Y mice. Most significantly, regulated genes were classified into functional categories of cell signaling/apoptosis/cell cycle, oxidative stress/aging, and cytoskeleton/extracellular matrix/transport‐associated. Analysis with EASE software indicated that the functional categories significantly overrepresented in Hq/Y mice included up‐regulated mitochondrial genes and down‐regulated cytoskeletal organization‐ and neurogenesis‐related genes. Our results strongly support the Hq/Y mutant mouse being a novel model for mechanistic studies of oxidative stress–associated olfactory aging. © 2007 Wiley‐Liss, Inc.
Blind identification and equalization of MIMO FIR channels based on second-order statistics and blind source separation

In the single-user scenario in data communications, the identification and equalization of the channel can be accomplished blindly (i.e., without training sequences) using second-order statistics (SOS) if suitable diversity in the received signal is exploited. Diversity can be temporal, spatial, or both. In this paper one well known SOS based blind identification and equalization (BIE) of communication channels is extended to the multi-input scenario. It is shown that the application of this SOS-BIE procedure reduces the system to a problem of blind source separation (BSS) of instantaneous linear mixtures. The users' signals can then be recovered in a second stage through appropriate BSS techniques, typically requiring higher-order statistics.
Nano-composite polymeric insulating material of mixed addition for control of treeing deterioration

A purpose of this study is to establish a basic concept of originally designed nano-composite for long term high endurance to electrical treeing deterioration. The nano-composite designed by us was prepared by a mixed addition of azobenzoic compound and Al2O3 nano-particle into LDPE. Through tests, 4'-hydroxyazobenzene-2-carboxylic acid (hc_Ab) was selected from six kinds of azobenzoic compounds as a candidate which will provide the long term performance. Experimental results under a room temperature with test materials before an accelerated aging procedure showed that when `hc_Ab' was adopted as a compound for the mixed addition, tree initiation voltage was increased to about 1.2 times higher than that for a single composite with `Al', which was about 1.8 higher than that for basic polymer (LDPE); An incubation time (a period of time from voltage application to tree appearance) was almost 1000 times longer than that for the base polymer under the constant applied voltage. It was experimentally suggested that absorption of electron's kinetic energy can be obtained by excitation of `hc_Ab' and cohesion of nano-particles can be controlled in the bulk of the nano-composite using `hc_Ab', which will provide the high performance for the tree control. A long term endurance test is carrying out under high temperatures, 87 °C, 92 °C and 95 °C. Properties for evaluations of the endurance are change in weight, dissipation factor and UV absorption characteristics. After 2500 h from a start of aging, a change of 0.5 wt% in weight was detected with the mixed addition under 95 °C. By contrast, the change of the basic polymer was 2 wt%. The incubation time of the mixed addition was kept almost unchanged from an initiation stage.
Late Quaternary Atmospheric CH4 Isotope Record Suggests Marine Clathrates Are Stable

One explanation for the abrupt increases in atmospheric CH4, that occurred repeatedly during the last glacial cycle involves clathrate destabalization events. Because marine clathrates have a distinct deuterium/hydrogen (D/H) isotope ratio, any such destabilization event should cause the D/H ratio of atmospheric CH4 (δDCH4) to increase. Analyses of air trapped in the ice from the second Greenland ice sheet project show stable and/or decreasing δDCH4 values during the end of the Younger and Older Dryas periods and one stadial period, suggesting that marine clathrates were stable during these abrupt warming episodes. Elevated glacial δDCH4 values may be the result of a lower ratio of net to gross wetland CH4 emissions and an increase in petroleum-based emissions.
Regras monetárias e restrição fiscal: uma análise da política de metas para a inflação no Brasil

Neste trabalho desenvolve-se um modelo de expectativas racionais baseado no paper de Batini e Haldane (1999) com o proposito de avaliar se as regras monetarias derivadas sob o regime de metas para a inflacao podem ser adaptadas para corrigir desvios explosivos da divida publica. Em paises emergentes, estes desvios sao um dos principais responsaveis pelas recentes crises. Atraves da endogeneizacao do premio de risco e a definicao de uma regra de decisao aumentada para o banco central, permite-se caracterizar a dinâmica de curto e longo prazo da relacao divida-PIB sob diversas oticas. Os resultados mostram que apesar da potencial solvencia de longo prazo, a divida ainda pode gerar preocupacoes no curto prazo, mesmo se o banco central considerar na sua reacao de politica problemas com a administracao da divida e atuar com base na previsao de inflacao.
XII Annual Meeting of the Interuniversity Institute of Myology

Muscle regeneration is a multistep process that is regulated by a restricted number of transcription factors whose activity is modulated at multiple levels. However, how different layers of regulation are coordinated to promote adult myogenesis is not yet understood. Here we show that the MEF2C transcription factor controls multiple steps of muscle regeneration, including myogenic progression of satellite cells and muscle maturation of newly generated myofibers, exhibiting multiple functions that depend on alternative splicing and post-translational modifications. Inclusion of the α1 exon in Mef2c transcripts is upregulated in proliferating mouse satellite cells and in the early phases of muscle regeneration. The encoded MEF2Cα1 isoform stimulates expansion of primary myoblasts ex vivo and in vivo. The pro-proliferative activity of MEF2C is mediated by phosphorylation of two phosphoserines located in exon α1. Subsequent terminal differentiation and growth of newly formed myofibers are promoted by dephosphorylated MEF2Cα1 and MEF2Cα2. Our results thus reveal an important role for regulatory interactions between alternative splicing and post translational modifications of a single transcription factor in the control of the multilayered regulatory programs required for adult myogenesis.
A deep learning / neuroevolution hybrid for visual control

This paper presents a deep learning / neuroevolution hybrid approach called DLNE, which allows FPS bots to learn to aim & shoot based only on high-dimensional raw pixel input. The deep learning component is responsible for visual recognition and translating raw pixels to compact feature representations, while the evolving network takes those features as inputs to infer actions. The results suggest that combining deep learning and neuroevolution in a hybrid approach is a promising research direction that could make complex visual domains directly accessible to networks trained through evolution.
AC-coupling and 1/f noise effects on baseband OFDM signals

The effect of AC-coupling and 1/f noise on baseband orthogonal frequency-division multiplexing (OFDM) signals is investigated. A system model that employs features of the packet format of existing wireless communication standards is used. The model assumes sampling and frequency-estimation errors at the receiver, and also imperfect channel-response estimation. The error vector magnitude (EVM) is selected as the performance evaluation criterion due to the simplicity in its evaluation, and because it allows for an easier comparison with the standards specifications. Simulation results are presented along with analytical expressions for the EVM, which provide system-design guidelines. Finally, simulation results are used to observe the intersymbol interference that is introduced as the AC-coupling filter impulse response exceeds the guard interval of the OFDM symbols
Cloud mobile media

Recent years have witnessed the blooming of mobile devices and applications. Mobile users not only expect a faster broadband connection to access Internet and interact with each other, but also demand ubiquitous enjoying of video contents and services. However, this trend is seriously hindered by the fact that mobile devices have limited resources in terms of computation, storage, power energy, etc., while media-rich applications are commonly resource-hungry. Fortunately, the emerging cloud computing paradigm offers a natural solution to extend the desktop visual experience to mobile devices.
Establishing a fracture liaison service: an orthopaedic approach.

➤ Bone health evaluations should be incorporated into care pathways for fragility fractures in all patients who are fifty years of age or older. ➤ A fracture liaison service (FLS) is an established and proven method to achieve recommended standards of care for fragility fractures, including intervention for osteoporosis, secondary fracture prevention, and bone health evaluation. ➤ The FLS facilitates patient care by automatically including all patients with a fragility fracture within a health-care system to provide them with the intervention that they need and to prevent avoidable fracture-related complications or readmissions. ➤ An FLS functions with three key personnel: the FLS coordinator (usually an advanced practice provider), a physician champion (usually an orthopaedic surgeon), and a nurse navigator.
The syntactic complexity of Russian relative clauses q

Although syntactic complexity has been investigated across dozens of studies, the available data still greatly underdetermine relevant theories of processing difficulty. Memory-based and expectation-based theories make opposite predictions regarding fine-grained time course of processing difficulty in syntactically constrained contexts, and each class of theory receives support from results on some constructions in some languages. Here we report four self-paced reading experiments on the online comprehension of Russian relative clauses together with related corpus studies, taking advantage of Russian’s flexible word order to disentangle predictions of competing theories. We find support for key predictions of memory-based theories in reading times at RC verbs, and for key predictions of expectation-based theories in processing difficulty at RC-initial accusative noun phrase (NP) objects, which corpus data suggest should be highly unexpected. These results suggest that a complete theory of syntactic complexity must integrate insights from both expectationbased and memory-based theories. 2013 The Authors. Published by Elsevier Inc. All rights reserved.
A gated 31P NMR method for the estimation of phosphocreatine recovery time and contractile ATP cost in human muscle

Muscle phosphocreatine (PCr) recovery time constant (an index of muscle aerobic capacity) and contractile ATP cost were estimated from a gated 31P NMR protocol which does not require intense, repetitive exercise. Subjects performed 2‐s duration, maximum voluntary isometric ankle dorsiflexion contractions at 30‐s intervals for 8 min (total 15 contractions), while single‐shot 31P spectra (51.7 MHz, TR 3 s) were acquired from the anterior compartment muscle. Spectra from the sixth through 15th contractions were retrospectively sorted, yielding 10 spectra (each 10 averages) gated to times before and after contraction. There was no significant decrease in muscle pH, allowing the calculation of contractile ATP cost directly from the percentage change in PCr during contraction cycles [8.86 ± 0.82% (SE, n = 11) of PCr at rest], corresponding to an ATP cost of 1.69 ± 0.16 mM/s (range 0.99–2.49 mM/s), assuming an 8.2 mM ATP concentration. The time constant for PCr recovery (τ 41.8 ± 4.2 s, range 22.0–60.8 s) was calculated from τ = −Δt/ln[D/(D + Q)], where Q is the percentage change in PCr due to contraction, D is the additional steady‐state percentage drop in PCr from rest and Δt is the interval between contractions. In the same subjects, the monoexponential PCr recovery time constant after more intense, repetitive isometric ankle dorsiflexion exercise (30 s at 0.5 Hz, 50% duty cycle) was similar to (36.2 ± 3.5 s, range 16.5–58.8 s) and well correlated with (r = 0.82) the gated result. In contrast to the gated protocol, muscle pH decreased from 7.01 ± 0.01 to 6.78 ± 0.04 during recovery after the repetitive protocol. Hence the gated protocol allows the estimation of muscle ATP cost and PCr recovery without intense exercise or muscle acidification. Copyright © 2006 John Wiley & Sons, Ltd.
Evaluation of the Severity of Dementia Using Expectation Control Function

The results of an animal experiment without anesthesia suggested the presence of expectation control in which sympathetic nerve tone increases at rest immediately before behaviors to prepare for the subsequent behavior. We investigated whether such function is present in humans in their daily living and whether patients with dementia could be differentiated from healthy adults based on this finding. Using a Holter electrocardiograph with an acceleration sensor, electrocardiograms (ECG) and behavioral states were recorded. The total recorded ECG was divided by 20 sec, and high (HF, 0.15–0.4 Hz) and low (LF, 0.03–0.15 Hz) frequency components were extracted by frequency analysis of the RR interval. We used the HF component, L/H ratio, and RR interval as the index grade of parasympathetic/sympathetic nerve tone. The mean value of each parameter was calculated and compared between the time zone during which resting persisted for 1 min or more (3 intervals) and that during which behaviors occurred immediately after a 1-min rest. In 32 patients with dementia, Holter ECG and behaviors were serially recorded, and the time zone during which intentional behaviors occurred was detected. RR interval and HF component decreased and L/H increased. Increasing in sympathetic nerve tone was observed at rest condition immediately before intentional behaviors, suggesting a presence of expectation control function. The expectation control mechanism will present inhumans and involved in this function by severity of dementia. This parameter may be useful for objectively evaluating the severity of dementia.
Anomalous transport and the coupling of plasma diffusion and heat flow.

Anomalous transport has been observed in heat-pulse tokamak experiments in the form of faster thermal diffusion than expected from thermal conductivity alone. The anomaly is resolved by correct treatment of time-dependent transport, coupling heat flow and plasma diffusion. The diffusion rates are exhibited as invariant eigenvalues appearing in the transport model. We show how these eigenvalues couple the basic transport processes. The thermal diffusion rate is not determined by thermal conductivity, since it is not an eigenvalue with temperature as eigenmode.
Implementation of matrix rhythm therapy and conventional massage in young females and comparison of their acute effects on circulation.

OBJECTIVES To examine and compare the effects of massage and matrix rhythm therapy in young women on the peripheral blood circulation. DESIGN Randomized, double-blind, controlled trial. SETTING Pamukkale University in Denizli, Turkey. PATIENTS Fifteen healthy women age 19-23 years. INTERVENTION Matrix rhythm therapy was applied to the left lower extremity for a single 30-minute session. At least 1 week later, massage was applied to the left lower extremity for 30 minutes in a single session. The same physiotherapist applied both sessions. OUTCOME MEASURES The blood velocity (cm/s), artery diameter (mm), and blood flow (ml/min) of the popliteal and the posterior tibial arteries were measured with color Doppler ultrasonography. All images were evaluated by the same radiologist. RESULTS After matrix rhythm therapy and massage application, blood velocity, artery diameter, and blood flow in arteries increased. However, matrix rhythm therapy caused a more prominent increase in the amount of blood flow in the popliteal and in the posterior tibial artery than did massage. After matrix rhythm therapy application, the average increases in the blood flow rates in the popliteal and the posterior tibial arteries were 25.29%±16.55% and 34.33%±15.66%, respectively; after the massage, the increases were 17.84%±17.23% and 16.07%±10.28%, respectively. CONCLUSION Matrix rhythm therapy and massage increased peripheral blood flow in young women. Matrix rhythm therapy method resulted in more prominent increases.
Register array-based VLSI architecture of H.265/HEVC loop filter

: A high-performance VLSI architecture for H.265/HEVC loop ﬁlter is proposed. The architecture is implemented by a parallel register array that consists of 8 × 8 registers with two data ﬂow directions. The register array computes the sub-blocks of four diﬀerent coding tree blocks at the same time based on the analysis of the computation order. This leads to the small number of registers used in the register array. The architecture computes 4 K UHD at 30 fps in real-time. The size of the synthesized design is 54 K gates. The operating clock frequency is 225 MHz in TSMC 65 nm process. If the degree of parallelism is increased to four, the architecture can compute up to 8 K UHD at 60 fps.
ERP system fit - an explorative task and data quality perspective

Purpose – The purpose of this paper is to facilitate understanding of enterprise resource planning (ERP) system and data quality interdependency by presenting ERP systems’ use within data quality management. Design/methodology/approach – The authors apply task technology fit (TTF) in an explorative study, conducting semi-structured expert interviews with participants in information technology strategic decision making. The authors analyzed the interviews with iterative descriptive and subsequent interpretive coding. Findings – Although considered sustainable, continuously increasing regulations challenge ERP systems. However, compliance with regulations may serve as a bridge for organizations to engage in data analysis. Organizations are embedded into evolving task environments with the need to continuously adapt their systems or the organization and the need for contextual understanding of data quality. Research limitations/implications – With ERP systems being used for administrative functions, future r.
Activation of the Diguanylate Cyclase PleD by Phosphorylation-mediated Dimerization*

Diguanylate cyclases (DGCs) are key enzymes of second messenger signaling in bacteria. Their activity is responsible for the condensation of two GTP molecules into the signaling compound cyclic di-GMP. Despite their importance and abundance in bacteria, catalytic and regulatory mechanisms of this class of enzymes are poorly understood. In particular, it is not clear if oligomerization is required for catalysis and if it represents a level for activity control. To address this question we perform in vitro and in vivo analysis of the Caulobacter crescentus diguanylate cyclase PleD. PleD is a member of the response regulator family with two N-terminal receiver domains and a C-terminal diguanylate cyclase output domain. PleD is activated by phosphorylation but the structural changes inflicted upon activation of PleD are unknown. We show that PleD can be specifically activated by beryllium fluoride in vitro, resulting in dimerization and c-di-GMP synthesis. Cross-linking and fractionation experiments demonstrated that the DGC activity of PleD is contained entirely within the dimer fraction, confirming that the dimer represents the enzymatically active state of PleD. In contrast to the catalytic activity, allosteric feedback regulation of PleD is not affected by the activation status of the protein, indicating that activation by dimerization and product inhibition represent independent layers of DGC control. Finally, we present evidence that dimerization also serves to sequester activated PleD to the differentiating Caulobacter cell pole, implicating protein oligomerization in spatial control and providing a molecular explanation for the coupling of PleD activation and subcellular localization.
Multi-scale design in layered synthetic biological systems

Synthetic biologists rely on mathematical modelling to predict and tune the behaviour of experimentally implementable biomolecular systems. In addition to electronic engineering and control/system theoretic ideas, other characteristic properties of biological systems can be used to achieve complex behaviours. This paper considers the use of timescale separation and layered architectures in synthetic biomolecular systems. We discuss how, by constructing a biomolecular reaction network on two timescales, we are able (a) to implement nonlinear, tunable constraints on a network's state independently of its slow-scale dynamics, and (b) to control the slow dynamics of a network's state in a constrained state space.