Miracle-dz/UniFAR-FTUs huggingface dataset:
COMPARATIVE STUDY OF COLLAGEN BASED DRESSING AND STANDARD DRESSING IN DIABETIC FOOT ULCER

Diabetic foot has become the common indication for hospital admissions among diabetics. The diabetic foot commonly begins as an ulcer. So rapid and extensive is the underlying damage that approximately 20% of these patients end up with amputation. Numerous dressings have been introduced that could help or hasten the healing process in foot ulcers. In this study, we have compared the efficacy of collagen granules in diabetic foot ulcers. 50 patients were divided into 2 groups of 25 patients each. One group received collagen dressing and the other group received standard saline dressings. The wound was reviewed on weekly basis for the maximum period of 12 weeks or till the wound healed spontaneously (whichever was earlier). We found collagen dressing to have statistically significant impact on the ultimate outcome (healing) in diabetic foot ulcers.
Lightweight localisation approach for WSNs: performance analysis and validation

Wireless sensor networks (WSNs) have become very popular in recent years due to their wide applications’ spectrum. One of the main issues arising while conceiving with WSNs functionality is the opportunity of developing a proper localisation algorithm that has to be tailored basing on hw/sw nodes limitations. This study proposes a localisation algorithm for WSNs based on received signal strength measurements whose results, although comparable with existing localisation algorithms, proves here to be of practical implementation on devices with very low computational capabilities as well as efficient in real-time usages. Extensive simulations and indoor/outdoor experimental measurements have been performed to verify the effectiveness of the proposed algorithm, taking also into account implementation issues on commercial sensor nodes.
Leucas aspera L. - Medicinal Herb

Leucas aspera commonly known as 'Thumbai' is distributed throughout India. The plants are curing various diseases like, asthma, skin disease, antifungal, antioxidant and antimicrobial acitivity. They usually prepare fresh juices, instead of boiling water and decoction leaves and flowers of Leucas aspera. The juice from the leaves can play a good roll in this matter. Leucas aspera are important ethno medicinal plants in Tamil Nadu.
Efficiency assessment of prostate cancer radiosurgical treatment on the CyberKnife system with the use of diffusion-weighted MRI (DW-MRI) with apparent diffusion coefficient (ADC) value assessment

Poster: "ECR 2012 / C-1122 / Efficiency assessment of prostate cancer radiosurgical treatment on the CyberKnife system with the use of diffusion-weighted MRI (DW-MRI) with apparent diffusion coefficient (ADC) value assessment" by: "O. Dudka, O. Sharaievskyi; Kapitanivka/UA"
Characterization and phylogenetic analysis of the complete plastome of Alopecurus japonicus (Gramineae), an annual weed

Abstract Alopecurus japonicus is a weed in summer crop field, which is harmful to wheat crops. The complete plastome of A. japonicus was reported in this study. The genome was 136,408 bp in length, consisting of an 80,512 bp large single-copy region, a 12,836 bp small single-copy region, and two 21,530 bp inverted repeat regions. The GC content of this plastome was 38.3%. A total of 112 genes were annotated for the plastome of A. japonicus, containing 78 protein-coding genes (PCGs), 30 tRNAs, and 4 rRNAs. Phylogenetic analysis showed that A. japonicus was sister to Alopecurus aequalis.
Family functioning and depression among Albanian migrants and Greeks in a rural area in Greece

Background: Albanian immigrants consist a large ethnic minority group in Greece and a significant proportion of local population in many areas of the country, including rural areas, such as in the Cyclades Islands (1). Even though migrants and their families are to various degrees integrated in the life of local communities, the factors associated with family dynamics and their relation to common mental health issues have not been much studied. There is evidence supporting an association between aspects of family dynamics and depression in adults (2-3). The aim of the current study was to explore the relationship between depressive symptomatology and family functioning in Albanian immigrants in a rural area in Greece. A comparison between Albanians and Greek natives was also made, in order to investigate if there were differences between the two ethnic groups, regarding the specific dimensions of family functioning associated with depressive symptomatology. Methods: The sample consisted of 204 adult service users, 105 (51,5%) Greeks and 99 (48,5%) Albanians, who sought help from the Mental Health Mobile Unit (EPAPSY-NGO) in Paros and Antiparos islands, during the years 2012-2016. The Family Assessment Device (FAD) (4-5) was used to assess perceived family functioning and the Centre for Epidemiologic Studies Depression Scale (CES-D) (6) was used to measure the current level of depressive symptomatology. Additional data was also recorded for every participant, including sociodemographic characteristics and psychiatric diagnosis (assigned by the psychiatrist). Results: More Greek service users in comparison to Albanians were categorised as perceiving to have healthy family functioning in the domains of ‘Communication’ (25.5% vs 10.1%, p<0.05) and ‘Affective Responsiveness’ (21% vs 6.6%, p<0.05) (according to the cut-off scores of FAD). Irrespective of nationality, better family functioning was related to less depressive symptoms. In Albanians, the specific dimension of family functioning referring to ‘Behaviour Control’ was independently associated with the score in depression scale, while in Greeks the ‘Problem Solving’ dimension was found to be significantly associated with depressive symptomatology. Conclusions: Differences were detected in certain domains of perceived family functioning between Albanian immigrants and Greek natives, regarding the categorization of healthy/unhealthy functioning. Association of family dynamics with depressive symptomatology was detected in both ethnic groups. Patterns of interaction in Albanian families, as expressed in roles, hierarchy, rules or standards, expectation of behaviour and discipline (Behaviour Control dimension of family functioning) were found to be related, independently of other factors, to depressive symptomatology. When working with migrants, it is important to evaluate different dimensions of family functioning and take them into consideration in order to improve prevention and intervention strategies developed by mental health services.
A Device for Fetal Monitoring by Means of Control Over Cardiovascular Parameters Based on Acoustic Data

The problem of monitoring fetal health is topical at the moment taking into account a reduction in the level of fertile-age women's health and changes in the concept of perinatal medicine with reconsideration of live birth criteria. Fetal heart rate monitoring is a valuable means of assessing fetal health during pregnancy. The routine clinical measurements are usually carried out by the means of ultrasound cardiotocography. Although the cardiotocography monitoring provides valuable information on the fetal health status, the high quality ultrasound devices are expensive, they are not available for home care use. The recommended number of measurement is also limited. The passive and fully non-invasive acoustic recording provides an alternative low-cost measurement method. The article describes a device for fetal and maternal health monitoring by analyzing the frequency and periodicity of heart beats by means of acoustic signal received on the maternal abdomen. Based on the usage of this device a phonocardiographic fetal telemedicine system, which will allow to reduce the antenatal fetal mortality rate significantly due to continuous monitoring over the state of fetus regardless of mother's location, can be built.
Investigating the molecular and cellular basis of pathogenesis in Huntington's disease.

Huntington’s disease (HD) is a late onset, neurodegenerative disorder that typically progresses for 10-20 years, resulting in premature death. Symptoms include choreic movement disorder, cognitive deficits and psychiatric disturbances. The neurodegeneration associated with HD occurs most prominently in the striatum with the additional involvement of the cortex and other brain regions in later stages. Initial neuropathology within the striatum demonstrates the selective vulnerability of medium spiny neurons. HD is inherited in an autosomal dominant fashion and is caused by the expansion o f a polymorphic trinucleotide (CAG) repeat within exon 1 o f the ubiquitously expressed HD gene. The expansion mutation results in an elongated poly glutamine stretch within the protein product, called huntingtin. An inverse correlation between the repeat number and age at onset/extent of pathology has been observed with the longest repeats causing severe juvenile HD. A knock-in HD mouse model has been created by homologous recombination, inserting a perfect CAG repeat tract (72-80 repeats) into exon 1 o f the mouse Hdh gene (Shelboume et a l , 1999), the mouse orthologue of the human HD gene. This HD knock-in mouse model provides an opportunity to explore the consequences of the HD mutation in its appropriate genomic and protein context. Previous studies o f the HD knock-in mice have demonstrated several alterations reminiscent of human HD, including behavioural changes (Shelboume et a l , 1999) and synaptic dysfunction (Usdin et a l , 1999). Protein aggregates, a cellular hallmark of the HD disease process, have been detected within the nucleus and neuropil of neurons selectively vulnerable to HD (Li et a l , 2000). The presence o f neuropil aggregates has also been associated with axonal degeneration (Li et a l , 2001). The alterations observed in HD knock-in mice occur in the absence of obvious cell loss, suggesting that this system maybe modelling the events involved in early HD pathogenesis. Movement disorder is a prominent symptom associated with human HD. Behavioural studies using sensitive, quantitative methods to assess motor function have been carried out in the HD knock-in mice. Gait abnormalities, at 9 months o f age, in the form o f altered weight distribution were observed and appeared to be influenced by the sex o f the mouse since significant alterations were restricted to male HD knock-in mice. In an attempt to assess cognitive deficits that may result from hippocampal synaptic dysfunction previously observed in HD knock-in mice, spatial learning and memory was also investigated. Experimental design problems prevented the acquisition of robust data from these experiments and the cognitive abilities of the HD knock-in mice remain unknown.
The Commonwealth Fund Survey of Physician Experiences with Managed Care

Physicians today are practicing in an environment few anticipated at the time they entered the profession. As managed care expands to cover an ever broader share of the population, more and more physicians are finding that they must ally themselves with managed care organizations if they wish to retain their existing patients or attract new insured patients. Some physicians are entering into individual contracts with health plans, while others are joining larger organizations that contract with health maintenance organizations (HMOs), preferred provider organizations (PPOs), or point-of-service (POS) plans. Still others choose to work directly for a staff or group HMO. These relationships are usually governed by complex contractual agreements that put financial and other controls--including mechanisms aimed at altering physicians' behavior and clinical decisions--into the hands of health plans.
Albumin, Leukosit, And Protrombin As Predictors Of Sepsis Mortality Among Adult Patients In Soetomo General Hospital, Surabaya, Indonesia

Introduction: Sepsis is presented as a complex and multifactorial syndrome where the morbidity and mortality rates still high around the world. Strong evidencewith regard to early predictive factors for mortality and morbidity is rare to be provided. Objective: The aim of this study was to analyse the prominent predictors from the values of laboratory findings among patients with sepsis. Method and Material: The study was an analytic observational study with a case-control approach. The data were extracted from patients' medical records between 2014 and 2015. This study involved 50 septic patients admitted to Dr. Soetomo General Hospital, Surabaya, Indonesia. Blood urea nitrogen (BUN), creatinine serum, albumin, leukocytes count, haemoglobin, hematocrite, platelets, sodium, potassium, chloride, prothrombin time (PT), and activated partial thromboplastin time (APTT) were collected from blood samples. Logistic regression was used to estimate sepsis related mortalities frequencies and the relationship between laboratory findings and under 28-days mortality. Result and Discussion: From 50 patients, 22 patients were died (44%). The regression model was intially conducted using all three biomarkers as covariates, then using backward elimination, the covariate with the highest p-value was eliminated. The process was repeated until covariates with statistically significant remained. Multivariate analysis showed that albumin, leukocytes count, and prothrombin time (PT) were the findings associated with high mortality. The independent predictors of mortality identified by further multivariate regression analysis were taken into account as a lower than 3.5 g/dL of albumin, above12.000/µL of leukocytes count, and prolonged more than 14 seconds of prothrombin time; with p value <0,05 respectively (0.029; 0.049; 0.027). Conclusion: Notably, low albumin level, elevated levels of leukocytes, and prolonged prothrombin time were clinically considered as independent predictors of mortality among adult patients with sepsis.
Educational attainment polygenic scores in Hungary: evidence for validity and a historical gene-environment interaction

Educational attainment is a substantially heritable trait, and it has recently been linked to specific genetic variants by genome-wide association studies (GWASs). However, some variants may index social stratification, and polygenic score (PGS) heritability may differ across cohorts reflecting the changing relative influence of genetic and environmental influences on educational attainment over time. We used a Hungarian (N=829) sample of healthy volunteers to assess the validity of the most recent educational attainment polygenic score in a population culturally and genetically different from the one used in GWAS discovery, as well as changes in PGS heritability over time. We used an English (N=976) sample with identical measurement protocols as comparison. We found that the PGS is valid in Hungary, accounting for 2-6.5% of the variance in educational attainment. We also replicated previous Estonian findings about generally increased PGS heritability in those attaining higher education after the fall of Communism, with PGS heritability up to 6.5% in the youngest cohort. In a comparable English sample the same PGS accounted for 9-11% of educational attainment variance. Our results provide evidence that polygenic scores for educational attainment are valid in diverse European populations. Our findings also provide further evidence that the fall of Communism, possibly along with other historical changes in education policy, was the source of a gene-environment interaction through which genetic factors became more important for higher educational attainment in those who graduated high school after this event.
A Bayesian Generative Model of Vestibular Afferent Neuron Spiking

Using an information criterion to evaluate models fitted to spike train data from chinchilla semicircular canal afferent neurons, we found that the superficially complex functional organization of the canal nerve branch can be accurately quantified in an elegant mathematical model with only three free parameters. Spontaneous spike trains are samples from stationary renewal processes whose interval distributions are Exwald distributions, convolutions of Inverse Gaussian and Exponential distributions. We show that a neuronal membrane compartment is a natural computer for calculating parameter likelihoods given samples from a point process with such a distribution, which may facilitate fast, accurate, efficient Bayesian neural computation for estimating the kinematic state of the head. The model suggests that Bayesian neural computation is an aspect of a more general principle that has driven the evolution of nervous system design, the energy efficiency of biological information processing. Significance Statement Nervous systems ought to have evolved to be Bayesian, because Bayesian inference allows statistically optimal evidence-based decisions and actions. A variety of circumstantial evidence suggests that animal nervous systems are indeed capable of Bayesian inference, but it is unclear how they could do this. We have identified a simple, accurate generative model of vestibular semicircular canal afferent neuron spike trains. If the brain is a Bayesian observer and a Bayes-optimal decision maker, then the initial stage of processing vestibular information must be to compute the posterior density of head kinematic state given sense data of this form. The model suggests how neurons could do this. Head kinematic state estimation given point-process inertial data is a well-defined dynamical inference problem whose solution formed a foundation for vertebrate brain evolution. The new model provides a foundation for developing realistic, testable spiking neuron models of dynamical state estimation in the vestibulo-cerebellum, and other parts of the Bayesian brain.
In Vitro Conservation of Medicinally Important Climbing Shrub Maerua Arenaria Hook. F. and Thomson

Caper family belongs to the order Brassicales comprises various important medicinal plants distributed in tropical countries. Maerua is the second largest genera in this family. Maerua arenaria is a wild climbing shrub having high medicinal value, due to over exploitation it becomes threatened. In vitro propagation technique has been adopted for conserving the valuable medicinal plant by using plant growth regulators. Initially the nodal explants were inoculated on MS medium supplemented with 4.0 mg/l BAP and 2.0 mg/l NAA for axillary bud proliferation. Multiple shoots (5-6 shoots per explant) were recorded after 34 days on MS medium with 2.0 mg/l BAP and 2.0 mg/l IAA. Since the shoots are small, they were transferred on MS medium containing 2.0 mg/l BAP and 2.0 mg/l GA3 for shoot elongation. These well developed elongated shoots were transferred to MS medium supplemented with 2.0 mg/l IBA for rooting. These in vitro developed plantlets were acclimatized in green house and successfully transplanted to natural condition and 78% of plants were survived.
Das Jahr des Distelfalters

Nach zehn Jahren erlebte Europa 2019 wieder einen Masseneinflug des Distelfalters (Vanessa cardui). Anfang Juni überfluteten die Wanderfalter Mitteleuropa geradezu. Für Verwunderung sorgte zunächst die Zugrichtung der Schmetterlinge, da sie vorwiegend in Ost‐West‐Richtung flogen. Bei dem letzten vergleichbaren Ereignis im Jahr 2009 fand der Einflug hingegen von Südwesten her statt. Aufschluss über den Verlauf und die Herkunftsregion der diesjährigen Wanderung geben zahlreiche internationale Medienberichte.
AVALIAÇÃO DA INTERFERÊNCIA DE DIFERENTES MÉTODOS DE COLHEITA DE SANGUE VENOSO NAS ANÁLISES LABORATORIAIS DE EQUINOS

Diversos fatores podem alterar uma amostra de sangue, sejam estes relacionados a tecnica de obtencao, manuseio e acondicionamento ou a afeccoes que acometem o paciente. O objetivo desse estudo foi avaliar a interferencia de diferentes metodos de colheita de sangue venoso nos resultados de exames bioquimicos comumente solicitados na pratica clinica de equinos. A metodologia aplicada envolveu a avalicao de amostras obtidas de 14 equinos machos clinicamente saudaveis, sem distincao entre raca e idade. Cada animal foi submetido a puncao nas veias jugulares direita e esquerda com o uso de agulha e seringa e pelo sistema de tubo a vacuo. As amostras foram submetidas a dosagens de hemoglobina livre, aspartato aminotransferase, lactato desidrogenase, potassio, glicose, hematocrito, proteina plasmatica total, proteina total serica e fibrinogenio. Os resultados demonstraram que, com excecao do fibrinogenio, nao houve diferenca entre os grupos. Conclui-se que, respeitando todos os principios de uma colheita de sangue ideal, nao ha interferencia do metodo de colheita nos resultados desses parâmetros bioquimicos.
A putative heat-responsive transcription factor (TaHD97) and its targets in wheat (Triticum aestivum) providing thermotolerance

Transcription factors (TFs) are protein, which perform their role at transcriptional level by affecting the expression of various genes associated with metabolic pathways, growth and stress-associated genes (SAGs) at different developmental stages. Here, we identified 38 novel heat-responsive transcription factor genes from wheat cv. HD2985 by mining the de novo transcriptome data derived from heat shock (HS) treated wheat. Based on digital gene expression (DGE), a putative transcript ( TaHD97 ) of ~1.1 kb was amplified and cloned from wheat cv . HD2985. The presence of heat stress transcription factor (HSF) DNA binding domain was observed in the amino acid sequence. Differential expression of TaHD97 was observed in HD2985 (thermotolerant) and HD2329 (thermosensitive) under heat stress. Tissue specific expression analysis showed up-regulation of TaHD97 in leaves, stem and endospermic tissues and down-regulation in root under HS. A positive correlation was established between the expression of TaHD97 and its target gene ( HSP17 and HSP90 ) in wheat under heat stress. HSP17 transcripts were observed more in leaves of HD2985, as compared to HD2329. Thermotolerance related biochemical enzymes (SOD, CAT, GPX and TBARS) were observed higher in wheat cv . HD2985 showing maximum expression of TaHD97 under heat stress. There is a need for the functional validation of the gene TaHD97 in order to use it for the regulation of sHSP (catalytic chaperone) - a novel approach towards augmenting thermotolerance in wheat under heat stress.
Effect of General Hospital Nurses' Perception of Patient Safety Culture and Burnout on Safety Management Activities

Purpose: The aim of this study was to examine effects of patient safety culture and burnout on safety management activities with a focus on clinical experience of nurses in general hospitals. Methods: Self-administered questionnaires were given to nurses in a general hospital in C Province, and 107 questionnaires were used for final analysis. Collected data were analyzed using SPSS/WIN 21.0 Program for t-test, ANOVA, Pearson correlation coefficients, and multiple regression. Results: The highest score as perceived by general hospital nurses for patient safety culture was for ‘Immediate superior/Manager’(3.84), for burnout, the highest score was for ‘Emotional exhaustion’ (4.13), and for safety management activities, the highest score was for ‘Prevention of infection’ (3.96). Patient safety culture and safety management activities perceived by general hospital nurses showed significant positive correlations (r=.35 p<.001). The correlations between burnout and safety management activities perceived by the nurses showed significant negative correlations (r=-.37, p<.001). Results of hierarchical regression analysis conducted to identify factors that affect safety management activities showed that patient safety culture (β=.40 p<.001) was effective for controlling safety management activities. Conclusion: The findings indicate a need to build a patient safety culture that fits the characteristics and situations of various hospitals.