Miracle-dz/UniFAR-FTUs huggingface dataset:
Uma Ontologia de Aplicação para Descrição de Indicadores de Poluição do Meio Ambiente(An Ontology to Describe Indicators of Environmental Pollution for the use of Applications)

Several projects have been developed with the aim to represent indicators for the environmental pollution following definitions of ISO 37120. The objective of these standards is to allow the comparison of indicators in different domains regarding the Smart Cities concepts. This paper proposes new constructs that extend ontologies derived from ISO 37120 to allow the description of indicators and indexes in a more refined way and under particular perspectives dictated by the needs of the end user. Indicators and indexes therefore, define visions about measurements of pollutants collected by sensing stations. Resumo. Diversos projetos têm sido desenvolvidos com o intuito de representar indicadores de poluição ambiental seguindo definições da norma ISO 37120. O objetivo desta norma é permitir a comparação de indicadores em diferentes domı́nios relacionados ao conceito de Cidades Inteligentes. Este artigo propõe novos construtos que estendem ontologias derivadas da ISO 37120 para permitir a descrição de indicadores e ı́ndices de modo mais refinado e de perspectivas particulares ditadas pelas necessidades do usuário final. Indicadores e ı́ndices definem, portanto, visões sobre medições de agentes poluentes coletadas por estações de sensoriamento.
Early Detection and Prevention of Breast Cancer: The Increasing Importance of Midwives in the Future

Breast cancer (BC) is the most common type of cancer and cause of death from cancer in women in the Republic of Slovenia. As in the majority of other economically and industrially developed countries, the incidence rate of BC is increasing in Slovenia and has reached 111.8 cases per 100,000 women in 2008. The incidence rate of BC has thus shown more than a fivefold increase in the period from 1950 to 2008 and BC was diagnosed in 1,147 women in 2008 (Cancer Registry of Republic of Slovenia, 2010). Similar increases in the incidence rates of BC have in the last decades also been observed in a number of other economically and industrially developed countries with aging female population (Curado et al (Eds.), 2009). However, the incidence rates of the BC are also rapidly increasing in a number of lowand middle-income countries (LMIC) (Forouzanfar et al, 2011), with more than half of all deaths caused by BC globally occurring in these countries (Curado et al (Eds.), 2009; Forouzanfar et al, 2011; International Agency for Research in Cancer, 2008). In LMIC countries, a sizeable proportion of women killed by BC were aged 15-49 years (Forouzanfar et al, 2011).
Non‐failure blood flow restricted exercise induces similar muscle adaptations and less discomfort than failure protocols

Low‐load blood flow restricted resistance exercise (BFRE) performed to volitional failure is suggested to constitute an effective method for producing increases in muscle size and function. However, BFRE to failure may entail high levels of perceived exertion, discomfort, and/or delayed onset of muscle soreness (DOMS). The aim of the study was to compare BFRE performed to volitional failure (F‐BFRE) vs non‐failure BFRE (NF‐BFRE) on changes in muscle size, function and perceptual responses. Fourteen young untrained males had one leg randomized to knee extension F‐BFRE while the contralateral leg performed NF‐BFRE. The training consisted of 22 exercise bouts over an 8‐week period. Whole‐muscle cross‐sectional area (CSA) of quadriceps components, muscle function, and DOMS were assessed before and after the training period. Perceived exertion and discomfort were registered during each exercise bout. Both F‐BFRE and NF‐BFRE produced regional increases in muscle CSA in the range of: quadriceps (2.5%‐3.8%), vastus lateralis (8.1%‐8.5%), and rectus femoris (7.9%‐25.0%). All without differences between leg. Muscle strength (6.8%‐11.5%) and strength‐endurance capacity (13.9%‐18.6%) also increased to a similar degree in both legs. Less perceived exertion, discomfort, and DOMS were reported with NF‐BFRE compared to F‐BFRE. In conclusion, non‐failure BFRE enables increases in muscle size and muscle function, while involving reduced perceptions of exertion, discomfort, and DOMS. Non‐failure BFRE may be a more feasible approach in clinical settings.
Frequency Correction Design Technique for Additive Manufactured Cavity Filters

In this work, a refinement of the classical coupled-cavity filter design technique is presented. This refinement consists of a central frequency correction when calculating inter-resonator cavity couplings. The correction introduced is specially critical when 3D shapings are applied to empty cavities, since both resonators and couplings become more dispersive, and frequency tuning is harder due to an increased sensitivity with the resonator geometry. To validate the design approach, a filter design with shaped cavities is realised, where it can be seen that the traditional design technique leads to a starting point which is significantly far from the target specifications. However, the use of the new technique increases the accuracy of its initial response, allowing a simpler final optimization process. The technique presented can have big impact in the efficient design of future filter structures, where 3D shapings are applied to improve performances.
Associations between testosterone and metabolic syndrome in depressed and non‐depressed older men and women

Older age and major depressive disorder (MDD) are both risk factors for the development of cardiovascular diseases. Testosterone has been associated with MDD and metabolic syndrome (MetS) in men, although associations in women are less clear. Therefore, we investigated whether testosterone is associated with MetS and whether this association is different for depressed and non‐depressed older men and women.
From a planned action to a revised action: revealing the structure of motor plans

We examined the effect of changing from an internally prepared motor plan to a revised action which potentially differed from the original plan along two dimensions: wrist orientation (horizontal or vertical) and left/right hand. Participants were instructed to prepare a particular hand grasp action and then were cued either to execute that motor plan or cancel it and plan a new action. In Experiments I and II, if the change from the original motor plan to an alternate response implied an action different from the prepared one, there was a slowing in response time. Moreover, if there was a change, maintaining the originally planned wrist orientation produced faster responses than changing orientation, but only if the response hand remained constant between planned and alternate actions and the cue was an image of a hand depicting a goal posture. In Experiment III, when the alternate action was cued by an image of an object inviting a particular grasp action, there was transfer only of the hand feature. In a final experiment, participants switched from a prepared action to naming a manipulable object. The motor features of the object differed from the original motor plan in the same way as in previous experiments. No effect of the previously cancelled motor plan was seen on naming latencies. These results elucidate the nature of motor plans and the role of motor actions in the representation of objects.
Artificial neural network based optical hand posture recognition using a color-coded glove

7 Acknowledgments 8 List of Figures 9 List of Tables 11 List of Abbreviations 12 Chapter 1 14 Introduction 14 1.1 Motivation 14 1.2 Problem Statement 16 1.3 Proposed Solution 16 1.4 Contributions 17 1.5 Thesis Outline 18 Chapter 2 20 Background 20 2.1 Immersive Virtual Reality 20 2.1.1 CAVE 21 2.1.2 DIVINE 22 2.1.3 VR Controllers 23 2.1.3.1 Instrumented Glove 24 2.1.3.2 3D Tracking 24
CtIP promotes G2/M arrest in etoposide‐treated HCT116 cells in a p53‐independent manner

Acquired resistance to cytotoxic antineoplastic agents is a major clinical challenge in tumor therapy; however, the mechanisms involved are still poorly understood. In this study, we show that knockdown of CtIP, a corepressor of CtBP, promotes cell proliferation and alleviates G2/M phase arrest in etoposide (Eto)‐treated HCT116 cells. Although the expression of p21 and growth arrest and DNA damage inducible α (GADD45a), which are important targets of p53, was downregulated in CtIP‐deficient HCT116 cells, p53 deletion did not affect G2/M arrest after Eto treatment. In addition, the phosphorylation levels of Ser317 and Ser345 in Chk1 and of Ser216 in CDC25C were lower in CtIP‐deficient HCT116 cells than in control cells after Eto treatment. Our results indicate that CtIP may enhance cell sensitivity to Eto by promoting G2/M phase arrest, mainly through the ATR‐Chk1‐CDC25C pathway rather than the p53‐p21/GADD45a pathway. The expression of CtIP may be a useful biomarker for predicting the drug sensitivity of colorectal cancer cells.
Éclosion de tuberculose chez les consommateurs de drogues et les sans-abri du Grand Montréal, Canada, de 2003 à 2016

Méthodologie : Tous les cas de tuberculose active ayant le génotype d’intérêt et résidant au Québec ainsi que les cas ayant un lien épidémiologique avec ces derniers ont été inclus dans l’investigation. Les données ont été extraites de façon rétrospective des enquêtes épidémiologiques de routine effectuées par les autorités de santé publique. Les caractéristiques des cas ont été décrites à l’aide du logiciel Excel. Une analyse spatiale des lieux fréquentés pendant les périodes de contagiosité des cas a été effectuée.
A Real-Time Non-Destructive Water Status Monitoring System at Terahertz Band

A novel water content monitoring system of a grapevine based on the reflectivity measurement on the plant trunk at the terahertz band is presented. In order to simulate different outdoor conditions, mainly temperature and lighting, the whole setup, which includes the grapevine and the measurement system, has been settled inside a growth chamber. Fluctuations of lighting conditions, temperature and irrigation have been correlated with variations of the signal power reflected on the trunk using both time domain broadband measurements and, magnitude and phase frequency domain narrowband measurements. The innovative setup enables the achievement of more reliable and accurate results when external conditions vary. Finally, the results have been contrasted, with high level of correlation, with long-established techniques using a dendrometer and a humidity probe.
VALOR, ESTRUTURA, PROCESSOS E OUTRAS DIMENSÕES MORFOLÓGICAS DA ORGANIZAÇÃO E DA ECONOMIA: UMA CONTRIBUIÇÃO À TEORIA SIMBIÓTICA DA ECONOMIA E À TEORIA DOS SISTEMAS

As redes, enquanto representacao estatica de um sistema dinâmico, expressam caracteristicas passiveis de servirem como subsidio para a compreensao da dinâmica interativa dos diferentes atores componentes de um sistema socioeconomico. Atraves de ferramental matematico especifico, e possivel construir um referencial teorico analitico para o entendimento das interacoes em ambientes socioeconomicos, sob o ponto de vista do agente ou sob a otica da analise do todo sistemico. Sao abordados conceitos como utilidade, beneficio, custo e as relacoes matematicas derivadas da compreensao de que essas variaveis delimitam todo tipo de acao social, do individual ao coletivo, fornecendo um referencial objetivo e contundente de analise das interacoes economicas, fundamentando as bases de um novo nicho exploratorio para a Teoria Simbiotica da Economia e a Teoria dos Sistemas.
The Art and Science of Operative Dentistry

-- The leading dental title in the world fully revised and updated to meet the challenges and needs of dental students and practitioners into the 21st century. -- An all new contemporary two-color format, four 8-page sections of new full-color photographs plus over 1200 new illustrations. Designed to be used by students throughout their dental education program and into professional clinical practice. Starting with dental anatomy and occlusion, it presents the most current information on cardiology, infection control, dental materials, and patient assessment -- including medical concerns. New techniques are presented so today's students and practitioners may incorporate them into their approach to providing the care that patients require and often demand. -- More detailed discussion of treatment planning and materials selection and a new and consistent format. -- Updated information about diagnosis and treatment planning, cardiology, infection control, dental materials, and patient assessment. -- Addition of procedural alternatives. -- Deeper and broader review of concerns regarding mercury. -- Information on complex restorations -- Specific information on advantages disadvantages indications, and contraindications for amalgam and composite restorations. -- Chapter outlines presented at the beginning of each chapter with page numbers indicating where each topic is discussed. -- Fully incorporates computer-assisted design and computer-assisted machining (CAD/CAM). -- Comprehensive list of references concludes each chapter.
Million Visual Analogue Scale Questionnaire: Validation of the Persian Version

Study Design Descriptive cross-sectional study. Purpose To validate the Persian version of the Million Visual Analogue Scale Questionnaire (MVAS), a self-administered low back pain (LBP) questionnaire. Overview of Literature The majority of LBP questionnaires translated into Persian evaluate the impact of LBP on daily living. The MVAS is one of the most commonly used self-administered LBP questionnaires, and was developed to assess a different direction and effect of activities of daily living on LBP intensity. Methods The questionnaire was translated into Persian with the forward-backward method and was administered to 150 patients randomly sampled from an occupational medicine clinic in Tehran in 2017. Results Cronbach’s alpha for all subscales ranged between 0.670 and 0.799. Confirmatory factor analysis showed adequate construct validity of the Persian version of the MVAS, with root mean square error of approximation 0.046, goodness of fit index 0.902, and comparative fit index 0.969. Other indexes were satisfactory. Conclusions The Persian MVAS is a valid and reliable instrument that can assess the effect of various daily activities on the intensity of LBP.
Generating Realistic Training Images Based on Tonality-Alignment Generative Adversarial Networks for Hand Pose Estimation

Hand pose estimation from a monocular RGB image is an important but challenging task. The main factor affecting its performance is the lack of a sufficiently large training dataset with accurate hand-keypoint annotations. In this work, we circumvent this problem by proposing an effective method for generating realistic hand poses and show that state-of-the-art algorithms for hand pose estimation can be greatly improved by utilizing the generated hand poses as training data. Specifically, we first adopt an augmented reality (AR) simulator to synthesize hand poses with accurate hand-keypoint labels. Although the synthetic hand poses come with precise joint labels, eliminating the need of manual annotations, they look unnatural and are not the ideal training data. To produce more realistic hand poses, we propose to blend a synthetic hand pose with a real background, such as arms and sleeves. To this end, we develop tonality-alignment generative adversarial networks (TAGANs), which align the tonality and color distributions between synthetic hand poses and real backgrounds, and can generate high quality hand poses. We evaluate TAGAN on three benchmarks, including the RHP, STB, and CMU-PS hand pose datasets. With the aid of the synthesized poses, our method performs favorably against the state-of-the-arts in both $2$D and $3$D hand pose estimations.
Design and Analysis of Novel Interconnects with Network-on-Chip LVDS Transmitter for Low Delay

In this paper, a novel global interconnect low voltage differential signaling (LVDS) transmitter for network-on-chip (NOC) has been proposed to achieve less global interconnect delay and low power dissipation. The proposed interconnect with transmitter has been examined in two different conditions, without buffer and with buffer in between interconnect and also impact of feature size scaling has been analyzed. The performance has been analyzed for the NOC interconnect with $0.350 \mu \mathrm {m}$ and $0.180 \mu \mathrm {m}$ CMOS technology. On scaling the technology with $0.350 \mu \mathrm {m}$ to $0.180 \mu \mathrm {m}$, the results show 15.68% global interconnect delay reduce for transmitter without buffer (Model-I) in between interconnect and with buffer (Model-II) global interconnect delay reduction of 15.83%. A significant reduction in power dissipation is achieved by selecting a proper sizing of transistor and using differential signaling technique of the data transmission. The power dissipation in $0.350 \mu \mathrm {m}$ technology is $1.78 \mathrm {m}\mathrm {W}$ and $0.180 \mu \mathrm {m}$ technology is $2.1929 \mathrm {m}\mathrm {W}$, respectively, at data rate of 2.9 Gbps and 3.5 Gbps at different technology for two different models.
Cycle shading for the assessment and visualization of shape in one and two codimensions

In this paper we propose cycle shading and hatched cycle shading as new local shading techniques for shape assessment and visualization. Natural surface highlights are extended to not only appear in isolated parts of a surface, but to reappear throughout the surface in a regular and easy-to-control pattern. Thereby even small surface variations become visible, wherever they are located on the surface. We further extend (hatched) cycle shading to curves in 3D, i.e., to shapes of higher codimension. We demonstrate how (hatched) cycle shading improves 3D vector field visualization by showing higher-order discontinuities of streamlines, pathlines, or streaklines. Our visualization approach is generic, simple, efficient, and can readily be used where Phong illumination is applicable because information on curvature or mesh connectivity is not required. The effectiveness of cycle shading for the assessment of surface quality is demonstrated by a user study. Finally, this paper addresses issues of anti-aliasing, parameter control, applications, and efficient GPU implementations.
Locus Coeruleus Phasic, But Not Tonic, Activation Initiates Global Remapping in a Familiar Environment

Locus coeruleus (LC) neurons, the source of hippocampal norepinephrine (NE), are activated by novelty and changes in environmental contingencies. Based on the role of monoamines in reconfiguring invertebrate networks, and data from mammalian systems, a network reset hypothesis for the effects of LC activation has been proposed. We used the cellular compartmental analysis of temporal FISH technique based on the cellular distribution of immediate early genes to examine the effect of LC activation and inactivation, on regional hippocampal maps in male rats, when LC activity was manipulated just before placement in a second familiar (A/A) and/or novel environment (A/B). We found that bilateral phasic, but not tonic, activation of LC reset hippocampal maps in the A/A condition, whereas silencing the LC with clonidine before placement in the A/B condition blocked map reset and a familiar map emerged in the dentate gyrus, proximal and distal CA1, and CA3c. However, CA3a and CA3b encoded the novel environment. These results support a role for phasic LC responses in generating novel hippocampal sequences during memory encoding and, potentially, memory updating. The silencing experiments suggest that novel environments may not be recognized as different by dentate gyrus and CA1 without LC input. The functional distinction between phasic and tonic LC activity argues that these parameters are critical for determining network changes. These data are consistent with the hippocampus activating internal network representations to encode novel experiential episodes and suggest LC input is critical for this role. SIGNIFICANCE STATEMENT Burst activation of the broadly projecting novelty signaling system of the locus coeruleus initiates new network representations throughout the hippocampus despite unchanged external environments. Tonic activation does not alter network representations in the same condition. This suggests differences in the temporal parameters of neuromodulator network activation are critical for neuromodulator function. Silencing this novelty signaling system prevented the appearance of new network representations in a novel environment. Instead, familiar representations were expressed in a subset of hippocampal areas, with another subset encoding the novel environment. This “being in two places at once” argues for independent functional regions within the hippocampus. These experiments strengthen the view that internal states are major determinants of the brain's construction of environmental representations.
Lymphocyte hydrogen sulfide production predicts intravenous immunoglobulin resistance in children with Kawasaki disease

Abstract The aim of the study was to identify whether lymphocyte hydrogen sulfide production is a potential biomarker to predict intravenous immunoglobulin (IVIG) resistance in children with Kawasaki disease (KD). This preliminary, single-center, case–control study conducted between June 2016 and March 2018 in Shaanxi Provincial People's Hospital, 85 children (50 with KD and 35 healthy controls) were included. Laboratory biomarkers were collected from the medical records. All patients with KD received 1 g/kg/d IVIG for 2 days and 30–50 mg/kg/d oral aspirin. The aspirin dose was reduced from 3 to 5 mg/kg/d after body temperature normalized. Plasma hydrogen sulfide levels were detected using sulfide electrode. Lymphocyte hydrogen sulfide levels were detected using the human hydrogen sulfide ELISA kits at the acute stage. Of 50 patients with KD, 31 and 19 were diagnosed with complete KD (cKD) and incomplete KD (iKD), respectively. Eleven patients with KD were resistant to IVIG treatment. The laboratory biomarker findings and levels of plasma and lymphocyte hydrogen sulfide were significantly different between the patients with KD and control group (P < .001). Moreover, lymphocyte hydrogen sulfide production was significantly greater in IVIG-resistant patients than in the IVIG-responsive patients, both in cKD and iKD (P = .018 and P < .001 respectively). Receiver operating characteristic curve indicated that when the lymphocyte hydrogen sulfide production was >15.285 nmol/min/108 lymphocytes, the sensitivity and specificity for predicting IVIG resistance were 90.9% and 76.9%, respectively. Lymphocyte hydrogen sulfide production could serve as a predictor of the therapeutic efficacy of IVIG in children with KD.