Miracle-dz/UniFAR-FTUs huggingface dataset:
Transit-supportive strategies for a successful new public transportation system in Riyadh

RESEARCH PAPER: Transit-supportive Strategies for a Successful New Public Transportation System in Riyadh STUDENT: Turki Alhedr DEGREE: Master of Urban and Regional Panning COLLEGE: Architecture and Planning DATE: July 2016 PAGES: 66 Public transportation is a very important element of any city and a necessity in metropolises. In Riyadh, Saudi Arabia’s capital and largest city with a population of more than five million, the government realized the pressing need for a comprehensive public transportation system. In 2012 the $22 billion King Abdulaziz Project for Riyadh Public Transport was announced. However, most public transit systems throughout the world are losing their competition with private vehicles and are thus operating at a loss. Riyadh’s new system will likely face additional difficulties due to special challenges such as the extreme hot weather and the socially conservative culture. Using a qualitative approach through reviewing the literature, examining governmental studies and academic researches, and studying real-life examples in case studies from different cities around the world, this research identifies the most effective pro-transit strategies that can help Riyadh’s new public transportation project be successful. While the recommended strategies were categorized as either system-related or complementary external strategies, more focus was put on the second group because of its greater importance and the less attention it receives.
Head and Neck Cancer in Saudi Arabia a Systematic Review A Systematic Review and Updates

Background Head and neck cancer (HNC) is the ninth most common cancer worldwide, and has a poor 5-year survival rate averaging 50%, which has not changed for decades. A high prevalence of HNC has been reported in the southwestern region of Saudi Arabia, as compared to other areas of the country. However, data in regards to HNC are scattered and not well documented. Thus, the aim of this systematic review was to gather all available and updated important information regarding HNC in Saudi Arabia, and highlight the gaps of knowledge in our country with regard to this disease. In addition, suggestions of solutions to overcome the current status and improve our future standard of care to fight HNC are also highlighted. Materials and Methods The electronic databases PubMed and Google Scholar using English-language literature were used for this systematic review, using specific inclusion and exclusion criteria and keywords. The search was performed in April 2016 and updated in June 2016. Results Our search revealed twenty-one studies that fulfilled our inclusion and exclusion criteria and that were conducted in Saudi Arabia. These studies investigated different aspects of HNC, including prevalence, risk factors, biomarkers, and assessed knowledge and awareness of both public and practitioners with regard to HNC. Conclusions This review uncovered a big gap in our epidemiological data in cancer information in general, and head and neck cancer in particular. In addition, a lack of knowledge and awareness of both the public and health care practitioners hinders the early diagnosis of disease and negatively impact the prognosis, treatment and outcome. The Ministry of Health in Saudi Arabia should develop a more systematic way and adapt policies to gather cancer information in general, and head and neck cancer in particular, from all governmental and private sectors from all over the kingdom, and develop educational programs to raise the knowledge and awareness of HNC in the country.
Detecção de Falhas em Processos Industriais Baseada no Algoritmo Evolutivo SOStream

In this paper, we propose the use of the online learning clustering algorithm, named as SOStream, to fault detection of industrial process operation. In order to carry out this activity, it was necessary to adapt the original algorithm for avoiding fault data to be approximately normal data clusters. Aiming to evaluate the performance of the SOStream, we performed a case study using the industrial plant simulator Tennessee Eastman Process. The analysis was done taking that into account multivariable monitoring scenarios, obtaining results above 90% in accuracy and recall. This, it was observed that the analyzed approach obtained good performance to fault detection. In addition, the algorithm SOStream has characteristics very interesting for real-time fault detection, such as unsupervised and online learning, data-driven approach and recursive, which does not require storing the previous samples. Resumo: Neste artigo, propomos a utilização do algoritmo evolutivo de clusterização online SOStream para detecção de falhas em processos industriais. Para isso, a metodologia proposta inclui uma adaptação no algoritmo original para evitar que dados de falha sejam sejam aproximados para clusters de dados normais. A fim de validar a metodologia, um estudo de caso utilizando o simulador de plantas industriais Tennessee Eastman Process foi realizado. A análise foi feita em uma sequência cont́ınua de dados, denominada de fluxo ou stream de dados, e de forma multivariável, obtendo-se resultados acima de 90% em precisão e recall. Essa abordagem evolutiva por ser baseada em dados e não supervisionada, torna o processo de detecção de falhas mais simples e com menor custo computacional quando comparado com as técnicas baseadas em modelos, além de possuir um dinamismo recursivo, não necessitando armazenar o histórico das amostras anteriores.
Nové možnosti v léčbě myelodysplastického syndromu

Myelodysplastický syndrom (MDS) je heterogenni skupina klonalnich onemocněni krvetvorne kmenove buňky, ktera se vyznacuje dysplastickými změnami prekursorů v kostni dřeni, periferni (pan) cytopenii a zvýseným rizikem progrese do akutni myeloidni leukemie (AML). V terapii MDS byly dlouhodobě využivany předevsim dvě zakladni modality: podpůrna pece nebo alogenni transplantace krvetvorných kmenových buněk (ASCT). V posledni době se vsak lecebne možnosti pro MDS nemocne významně rozsiřily. Vedle konvencně použivane terapie se objevily nove leky a jejich kombinace, ktere mohou ovlivnit přirozený průběh choroby a prodloužit přežiti. V klinicke praxi nachazeji největsi uplatněni hypometylacni latky, imunomodulans lenalidomid (LEN) a moderni chelatory.
Social Anxiety Reduction in the Context of Social Modeling Utilizing a Placebo Alcohol Beverage

Alcohol misuse and elevated social anxiety are found to be highly comorbid, and being exposed to social models consuming alcohol can increase one’s consumption. Yet no research has thus far examined whether the internal experience of alcohol consumption (e.g., social anxiety reduction) can also be transmitted via social modeling. This bar-lab study examined the impact of social modeling behavioral cues of social anxiety on emerging adult drinkers. It was hypothesized that those exposed to a social model experiencing an apparent social anxiety reduction from drinking would themselves report lessened state social anxiety following a placebo drink, and that this effect would be stronger for female participants. The final sample (N = 39) consisted of 21 men and 18 women ages 21-28 (Mage = 22 years; 54% White [nonHispanic]). All participants viewed a gender-matched videotaped social modeling manipulation and were randomly assigned either to a condition in which the confederate appeared socially anxious throughout the video (control) or ceased displaying social anxiety markers after consuming alcohol (treatment). State social anxiety was assessed both preand postmanipulation utilizing the State Social Anxiety Questionnaire (SSAQ). The social modeling manipulation was not found to impact SSAQ scores following placebo alcohol consumption. Further, gender did not moderate the effects. Across genders and conditions, there was a significant reduction in SSAQ scores post-drinking. Findings from this study suggest that future research may have to attend to additional factors if attempting to socially model social anxiety effects related to drinking. Floor effects for social anxiety in this non-clinical sample may have presented a barrier to detecting changes in state social anxiety. Additionally, the impact that preexisting alcohol expectancies and beliefs may have on this sort of research are not well understood.
Thermal Analysis of Power Semiconductor Device in Steady-State Conditions

Electronic devices can be damaged in an undesirable manner if the junction temperature achieves high values in order to cause thermal runaway and melting. This paper describes the mathematical model to calculate the power losses in power semiconductor devices used in bidirectional rectifier which supplies a resistive-inductive load. The obtained thermal model can be used to analyse the thermal behaviour of power semiconductors in steady-state conditions, at different values of the firing angle, direct current, air speed in the case of forced cooling, and different types of load. Also, the junction and case temperature of a power thyristor have been computed. In order to validate the proposed mathematical model, some experimental tests have been performed. The theoretical values are in good concordance with the experimental data and simulated results.
Sistemas de entrega de fármacos autoemulsificables: una plataforma de desarrollo alternativa para la industria farmacéutica colombiana

Los grandes avances tecnológicos en la industria farmacéutica, que involucran el uso de la química combinatoria y el cribado de alto rendimiento, han conllevado al descubrimiento de muchas entidades químicas candidatas a fármacos que presentan baja solubilidad acuosa, debido a su elevada complejidad molecular, lo que hace difícil el desarrollo de productos con estas sustancias. Los sistemas de entrega de fármacos autoemulsificables (SEDDS) han generado un interés para el desarrollo farmacéutico porque son una alternativa efectiva para mejorar la biodisponibilidad de fármacos poco solubles en agua. Para describir el estado de conocimiento sobre estos sistemas se realizó una revisión sistemática en diferentes bases de datos sobre la literatura relacionada con los SEDDS a nivel nacional e internacional, logrando así describir los aspectos más relevantes sobre los SEDDS (tipos, composición, mecanismos para aumentar biodisponibilidad, caracterización, formulaciones). A pesar de las numerosas investigaciones realizadas durante los últimos años que muestran el potencial de los SEDDS para mejorar la biodisponibilidad de los fármacos poco solubles en agua, se pudo evidenciar que solo algunas sustancias activas han sido incluidas en estos sistemas y comercializadas exitosamente, esto debido a algunas limitaciones que indican la necesidad de un mayor entendimiento sobre estos sistemas.
Molecular Response <1% BCR-ABL IS at 12 Months Is Associated with Improved Overall and Progression-Free Survival. the Randomized German CML-Study IV

Abstract 669 Introduction: The prognostic relevance of major molecular remission (MMR, Patients and Methods: We have analyzed 848 patients within the CML-Study IV (randomized comparison of imatinib 800 mg vs 400 mg vs 400 mg + IFN). BCR-ABL (IS) was determined by quantitative RT-PCR. Patients with atypical BCR-ABL transcripts were excluded from the analysis. Median observation time was 40 months (minimum 12). Landmark analyses have been performed at 12 months for overall and progression-free survival using 3 groups of response ( 1% BCR-ABL IS). Results: 341 patients achieved a BCR-ABL expression 1% by 12 months. Independent of treatment approach, the groups of patients achieving MMR and 0.1%- 1% BCR-ABL by 12 months (Figure). Conclusion: Faster and deeper response to imatinib-based treatment by 12 months revealed to be associated with improved PFS and overall survival. The critical cutoff level seems to be 1% BCR-ABL IS which has been shown to closely correlate with complete cytogenetic remission. Disclosures: Muller: Novartis: Honoraria, Research Funding. Schnittger: MLL Munich Leukemia Laboratory: Employment, Equity Ownership. German CML-Study Group: Deutsche Krebshilfe: Research Funding; Novartis: Research Funding; Roche: Research Funding; BMBF: Research Funding; Essex: Research Funding.
Results from a cognitive group rehabilitation programme from an occupational performance perspective

Introduction The Canadian Occupational Performance Measure (COPM) was used for treatment planning and to evaluate the effect of a cognitive group rehabilitation programme. The aim was to identify occupational performance problems defined as important and to analyse the outcome, and to link those problems to the International Classification of Functioning, Disability and Health (ICF) core set for traumatic brain injury and stroke. Method A retrospective design was used, including an analysis of COPM data recorded before and two months after the programme. COPM data from 124 clients were linked to the ICF core sets. Results A clinically important difference of ≥2 COPM scores was reached in 32% of the clients for occupational performance and in 47% for satisfaction with occupational performance. A majority of the problems identified (62%) were classified within the activities and participation component in the ICF, and 38% in body functions. All occupational performance problems could be linked to the ICF; just one of the 36 categories (caring for household objects) was not found in any of the ICF core sets. Conclusion By linking the COPM data to the core sets, occupational therapists can be confident in addressing the typical problems of the group of clients identified.
The Effect of the Extracts of Betel (Piper betel) Leaves on the Content of IL-1? as the Inflammatory Cytokine in Experimental Mice Using an Acute Wound Healing Modeling

This study aims to determine the effect of ethyl acetate derived from the leaves extraction of betel (Piper betel) on the content of Interleukin- 1β (IL - 1β) in experimental mice using an acute wound healing modeling. The experimental design used randomized post test only group with 72 experimental mice which divided into 4 groups and each group consisted of 6 mice with three replications. The negative control group (I) was given vaseline after incision. The positive control group (II) was given bioplasenton. The third group (III) was topically given the extracts of betel leaves at 2% concentration and the fourth group (IV) The quantitative analysis (statistical test) used complete randomized design using one-way anova with Spearman’s test and expressed as means±standard deviation, whereas, the qualitative analysis of the data was presented with the figure of time period of the concentration of IL- 1β for the negative control and control groups as well as both the extracts of betel leaves at 3rd day, 7th day and 14th day respectively. Results revealed that the content of IL- 1β was not statistically corr elated with both the negative and positive control groups for both the treatment of vaseline ( ρ ˂ 0,217, r = 0,218) and bioplasenton ( ρ ˂ 0,249, r = 0,190) respectively. In addition, the content of IL- 1β was also not statistically correlated with the treatment of the extracts of betel leaves at 2% concentration ( ρ ˂ 0,060, r = 0,420). In contrast, the content of IL- 1β was statistically correlated with the treatment group of the extracts of betel leaves at 3% concentration ( ρ ˂ 0,002, r = 0,701). Results of the study concluded that the treatment of extracts of betel leaves at 3% concentration affected wound healing process in experimental mice and increased in line with the ascending time in wound healing process, whereas, both the negative and positive control groups as well as the treatment group of the extracts of betel leaves at 2% concentration did not affect the wound healing process among experimental mice.
Towards a better understanding of postpartum depression : the professionals' perspectives

The relationship between mother and baby has been and remains one of the most basic and important relationships throughout the ages. However, not all relationships between mother and baby or father and baby are a bed of roses. With mental health problems on the rise it is no surprise that many parents are finding themselves affected negatively by the birth of their new-born. This study aims to improve the understanding of Postpartum Depression (PPD) whilst also delving into the various associated factors, issues relating to awareness, referral, treatment modalities, and outcomes through the perceptions of professionals in the field. The consequences of, and degree of societal awareness about the illness as well as strategies to assist sufferers are also considered. The study is done through a qualitative methodolgy with convergent and divergent themes. Our society has become somewhat more sensitive about this condition, allowing mothers and fathers to better understand the illness whilst being aware of the symptoms and warning signs. Unfortunately, more needs to be done, at various levels, to reduce the burden of this disease particularly on those directly affected and their relatives. “I confirm that this is my own work and that all material attributed to others (whether published or unpublished) has been clearly identified and fully acknowledged and referred to the original sources. I agree that the University has the right to submit my work for originality checks. ”
Prevalence of work-related musculoskeletal disorders among non-healthcare working population in different gender at Selangor

BACKGROUND: Musculoskeletal disorders were reported to occur in some industries and occupations with rates more than three or four times higher than the average rate across all industries. Most of the study has been done among healthcare population and results shows higher rate of prevalence. Meanwhile, very less surveys has been done on WRMSD among non-healthcare working population. Objective: To determine the prevalence of work related musculoskeletal disorders among non-healthcare working population in different gender at Selangor. Method: A self administered questionnaire was distributed to 300 subjects through convenient sampling method at 6 offices, 3 companies and 4 schools around Selangor. 240 subjects were responded to the questionnaire. Out of 240 subjects, 176 subjects has been included in this study and 20 subjects eliminated due to incomplete answers in questionnaires and 44 subjects excluded because they doesn't meet the inclusion criteria. The questionnaires of 176 subjects has been analysed and tabulated according to gender differences. Result: This study found that, the prevalence of WRMDs is significantly high among non-healthcare working population (77.3%) and women were reported to have more complaints of pain than men (78.8% vs. 74.6%). Conclusion: This study concluded that there is high prevalence of WRMDs among non-healthcare working population. Musculoskeletal disorders have negative impact on job performance and leisure activities. Language: en
Robust deflated principal component analysis via multiple instance factorings for dimension reduction in remote sensing images

Abstract. Remote sensing data are often adversely affected by noises due to atmospheric water absorption, transmission errors, sensor sensitivity, and saturation. Therefore, the performance of the classical principal component analysis (PCA) is negatively affected when dealing with such noisy data. To overcome this problem, a robust deflated PCA via multiple instance factorings (RDPCA-MIF) for dimension reduction in remote sensing images is proposed. In contrast to the traditional PCA, a penalty is imposed on the instance space through instance factoring technique to suppress the effect of noise in pursuing projections. To achieve this, we use two strategies, total distance, and cosine similarity metrics. Both strategies discriminate between noise and authentic data points by iteratively learning the relationship between instances and projections. Moreover, a deflation strategy that enables multiple relationships learning between instances and projections is applied to thoroughly evaluate the importance of instances in relation to all projections. Extensive experimental evaluations of the proposed RDPCA-MIF on Salinas-A dataset and shallow and deep features from the NWPU-RESISC45 remote sensing dataset prove its superiority over six comparative methods in dimension reduction and classification tasks.
Handling Sequence-dependent Setup Time Flexible Job Shop Problem with Learning and Deterioration Considerations using Evolutionary Bi-level Optimization

ABSTRACT Bi-level optimization is a challenging research area that has received significant attention from researchers to model enormous NP-hard optimization problems and real-life applications. In this paper, we propose a new evolutionary bi-level algorithm for Flexible Job Shop Problem with Sequence-Dependent Setup Time (SDST-FJSP) and learning/deterioration effects. There are two main motivations behind this work. On the one hand, learning and deterioration effects might occur simultaneously in real-life production systems. However, there are still ill posed in the scheduling area. On the other hand, bi-level optimization was presented as an interesting resolution scheme easily applied to more complex problems without additional modifications. Motivated by these issues, we attempt in this work to solve the FJSP variant using the bi-level programming framework. We suggest firstly a new bi-level mathematical formulation for the considered FJSP; then we propose a bi-level evolutionary algorithm to solve the problem. The experimental study on well-established benchmarks assesses and validates the advantage of using a bi-level scheme over the compared approaches in this research area to solve such NP-hard problem.
Addressing erectile dysfunction in prostate cancer survivors after radical prostatectomy

ABSTRACT Introduction: Erectile dysfunction is a common and severe adverse effect after radical prostatectomy for prostate cancer. Research on post-surgical erectile dysfunction has so far mostly focused on physiology, prevalence, related factors, and treatment. This review takes a broader approach adding an integrated theory of sexuality as well as social, relational, and psychological perspectives. Areas covered: In this updated review, we have incorporated recent data concerning erectile dysfunction after radical prostatectomy regarding theories of sexuality and masculinity, relevant aspects of sexual function, management of erectile dysfunction, psychological reactions to and interventions toward erectile dysfunction in men treated for prostate cancer, and finally social attitudes towards sex in elderly people. Expert commentary: The physiological and patient-only approach to erectile dysfunction after radical prostatectomy has definite limitations. In the future this problem must be approached in a broader perspective in order to reach optimal sexual life for the patients and their partners.
Novel Approach to Modeling the Seismic Waves in the Areas with Complex Fractured Geological Structures

This paper presents a novel approach to modeling the propagation of seismic waves in a medium containing subvertical fractured inhomogeneities, typical for mineralization zones. The developed method allows us to perform calculations on a structural computational grid, which avoids the construction of unstructured grids. For the calculations, the grid-characteristic method is used. We also present a comparison of the proposed method with the one described at earlier works and discuss the areas of its practical application. As an example, the numerical results for a cluster of subvertical fractures are given. A new approach for modeling fractures makes it quite easy to incorporate fractured objects into the seismic models and perform calculations without using algorithms on unstructured and curved grids.