Miracle-dz/UniFAR-FTUs huggingface dataset:
Utilizing Social Media for Identifying Drug Addiction and Recovery Intervention

Topic-specific social media forums such as Reddit have become popular platforms for users discussing health-related information as well as for scientific analysis of that information. Such discussions among users have been found to be effective in providing useful insights and assistance in many healthcare applications. This study focuses on one such application, where we utilize Reddit posts related to drug addiction and substance abuse, in order to help the addicted people. We observe some linguistic differences in the posts as users gradually move from the addicted stage to more and more advanced recovery stages. We then classify user-posts on Reddit as to be indicative of drug addiction or of different stages of recovery of the user. By annotating Reddit posts with the help of standard social and health psychology literature, we develop a Machine Learning classifier based on linguistic features, to classify the posts among different classes related to addiction and recovery. Finally, we identify addicted users having an intention to recover and develop a methodology for personalized mentor recommendation, whereby we identify potential mentors who are already in their advanced stage of recovery from usage of the same drugs as the target addicted user. To our knowledge, this work is the first attempt to utilize social media for helping addicted users having intention to recover with personalized mentor recommendations to facilitate their process of recovery.
1.3 kV Reverse-Blocking AlGaN/GaN MISHEMT With Ultralow Turn-On Voltage 0.25 V

A reverse-blocking AlGaN/GaN metal-insulator-semiconductor high electron mobility transistor (RB-MISHEMT) is proposed and fabricated. Compared with the conventional MISHEMT with ohmic drain, the proposed device features a hybrid Schottky-ohmic drain with a low work function Tungsten (W), based on which the state-of-the-art ultralow turn-on voltage (<inline-formula> <tex-math notation="LaTeX">${V} _{\mathrm{ on}}$ </tex-math></inline-formula>) of 0.25 V could be realized without degradation in on-state characteristics. In addition, the fabricated RB-MISHEMT exhibits the excellent reverse blocking voltage of −1332 V (at <inline-formula> <tex-math notation="LaTeX">${V} _{\mathrm{ GS}}= 0$ </tex-math></inline-formula> V) and forward blocking voltage of 1315 V (at <inline-formula> <tex-math notation="LaTeX">${V} _{\mathrm{ GS}} = -15$ </tex-math></inline-formula> V) with a specific on-resistance (<inline-formula> <tex-math notation="LaTeX">${R} _{\mathrm{ on,sp}}$ </tex-math></inline-formula>) of 3.5 <inline-formula> <tex-math notation="LaTeX">$\text{m}\Omega $ </tex-math></inline-formula>cm<sup>2</sup>, leading in the highest power figure-of-merit (FOM) of > 494 MW/cm<sup>2</sup>. The good thermal stability could also be observed in fabricated RB-MISHEMT. The corresponding operation mechanism of RB-MISHEMT are also revealed by Silvaco ATLAS simulations. These results demonstrate the great potential in power electronics applications.
Physics-based turbulence models for large-eddy simulation : Theory and application to rotating turbulent flows

Fluid flows are everywhere. Consider, for example, rivers, the flow of air in the atmosphere and the blood that is flowing through our veins. Most fluid flows are very chaotic, or turbulent, and the prediction of their behavior is essential for many applications, including the design of cars, boats and airplanes. However, accurately predicting turbulent flows is very challenging because computers do not have enough memory to store all flow details. In this thesis, we, therefore, apply a method called large-eddy simulation. With this method, the large eddies, or vortices, in flows are directly computed, whereas small eddies have to be described using turbulence models. The question we consider is: how to create physics-based turbulence models, which respect the physical and mathematical properties of flows? To answer this question, we follow a systematic approach. We thereby obtain a framework of constraints for the construction of physics-based turbulence models. Using this framework, we show that existing turbulence models do not respect all properties of flows. We also illustrate how new physics-based turbulence models with desired properties can be created systematically. We then apply the framework of constraints to develop a new turbulence model for rotating flows. We show that this model respects many properties of flows and provides outstanding predictions of rotating flows. We also demonstrate that these predictions are as good as, or much better than, predictions from existing turbulence models. Our work can, thus, aid in improving predictions of both rotating and nonrotating turbulent flows.
Bioinformatics analysis of hematopoietic injury and potential therapeutic drugs associated with SARS-CoV-2 infection

Objective To analyze and predict hematopoietic injury caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and potential therapeutic drugs, and to provide theoretical basis for clinical treatment of the hematopoietic injury. Methods The gene expression omnibus (GEO) database was used to screen the whole genome expression data related to SARS-CoV-2 infection. The R language package was used for differential expression analysis and the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) enrichment analysis. The core genes were screened by protein-protein interaction (PPI) network analysis using STRING online analysis website. Then the self-developed apparent precision therapy prediction platform (EpiMed) was used to analyze diseases, drugs and related target genes. Results A total of 222 differential genes were screened, including 172 up-regulated and 50 down-regulated. GO enrichment analysis suggested that gene is mainly related to type I interferon response, cell cycle regulation, inflammatory cell migration, innate immune response, secretion of blood particles and vesicles, chemokines and their receptors. KEGG enrichment analysis suggested that gene is mainly related to viral infection, myocardial injury, complement and coagulation cascade, cell chemotaxis, platelet activation, acute inflammation, immune response, cellular signal transduction and so on. Ten core genes such as STAT1, IL-6, IRF7, TNF, MX1, ISG15, IFIH1, IRF9, DDX58 and GBP1were screened by PPI network analysis. EpiMed screened 10 drugs with potential intervention effects, including Rabdosia rubescens, sirolimus, glucocorticoid, Houttuynia cordata, Polygonum multiflorum, Red peony, tretinoin, Glycyrrhiza, cyclosporine A, fluvastatin and so on. Conclusions SARS-CoV-2 infection can damage the hematopoietic system by changing the expression of a series of genes. The potential intervention drugs screened from this have certain reference significance for the basic and clinical research of coronavirus disease 2019 (COVID-19). DOI: 10.11855/j.issn. 0577-7402.2020. 09.08
Capacity Gain of Full Duplex Self-Backhauling and Opportunistic Full Duplex Self-Backhauling

This paper investigates the capacity gain of full duplex (FD) self-backhauling over the half duplex (HD) counterpart in downlink cellular systems, and then proposes an opportunistic FD scheme. The first step is to derive the capacity gain of FD self-backhauling over the HD counterpart as a function of the system parameters in a computationally tractable form. Unlike previous studies on the capacity of FD self-backhauling, a practical constraint is imposed so that the end-to-end link achieves a target signal-to-interference-plus-noise ratio (SINR) for a successful link connection. Also, a condition under which FD is more beneficial than HD is derived. Specifically, the minimum allowable self interference cancellation factor and the maximum allowable cell radius for the benefit of FD are derived as an explicit function of system parameters. Their dependencies on the system parameters are investigated and compared with counterparts derived for single-hop point-to-point links. Lastly, to overcome the weak points of FD and HD, this paper proposes a user-wise opportunistic FD (OFD) self-backhauled scheme. To this end, an instantaneous channel gain-based FD/HD switching rule is derived from a condition under which FD cannot instantaneously satisfy the target SINR. We confirm the substantial capacity gain of the proposed user-wise instantaneous OFD over a cell-wise static duplex switching scheme, as well as the fixed duplex (HD or FD) schemes. When compared to the static duplex switching scheme, the proposed OFD is most beneficial at the boundary of HD-preferred and FD-preferred regions. Based on this, a system-level guideline is proposed for selecting the most practical scheme among OFD, FD, and HD by trading off capacity gain and switching overhead. Extensive simulation results are provided to confirm the correctness of the derivations and the related investigations.
Analysis of a New Partitioned-Primary Flux-Reversal Hybrid-Excited Linear Motor

A new partitioned-primary flux-reversal hybrid-excited linear motor is proposed and investigated in this article, which features an asymmetrical double-sided primary structure. The novelty of this motor lies in the adoption of a partitioned-primary structure by moving the field excitation winding to an additional primary, thus it benefits from improved space utilization ratio since both armature and field windings can be separately mounted. First, the topology, feasible slot/pole combinations, and operating principles of the proposed machine are introduced. The magnetic flux density distributions in two air-gap regions are comparatively studied from the perspective of magnetic gearing effect. Then, global optimization of the proposed motor with different slot/pole combinations is performed to maximize both the output thrust force and flux-adjusting range based on 2-D finite-element analysis (FEA). In addition, the electromagnetic performance of the motors including flux-adjusting capability, thrust force, detent force, and force ripple with different slot/pole combinations are comparatively investigated. Finally, a 6-slot/7-pole prototype is manufactured and tested to verify the FEA and calculations. It is shown that the proposed motor, benefiting from a partitioned-primary topology, exhibits very good flux-adjusting capability and overloading capacity. Thus, it has good prospect in applications that require flexible speed control.
3TC-DTG Dual Therapy and Its Implications in Hepatic Steatosis in People Living With HIV

Moschese D1,3*, Ciccullo A1,3, Taccari F1, Emiliozzi A1, Baldin G2, Picarelli C1,3, Dusina A1,3, Lombardi F1, Belmonti S1, Borghetti A3 and Di Giambenedetto S1,3 1Department of Safety and Bioethics Infectious Diseases Section, Catholic University of Sacred Heart Rome, Italy 2Department of Safety and Bioethics Olbia Mater Hospital Olbia, Italy 3Department of Safety and Bioethics Fondazione Policlinico Universitario “Agostino Gemelli” IRCCS Rome, Italy
The Impact of Elastic Deformation on Deposition Kinetics at Lithium/Polymer Interfaces

Department of Chemical Engineering, University of California, Berkeley, California 94720-1462, USAPast theories of electrode stability assume that the surface tension resists the ampliﬁcation of surface roughness at cathodes andshow that instability at lithium/liquid interfaces cannot be prevented by surface forces alone @Electrochim. Acta, 40, 599 ~1995! #. This work treats interfacial stability in lithium/polymer systems where the electrolyte is solid. Linear elasticity theory is employedto compute the additional effect of bulk mechanical forces on electrode stability. The lithium and polymer are treated as Hookeanelastic materials, characterized by their shear moduli and Poisson’s ratios. Two-dimensional displacement distributions that satisfyforce balances across a periodically deforming interface are derived; these allow computation of the stress and surface-tensionforces. The incorporation of elastic effects into a kinetic model demonstrates regimes of electrolyte mechanical properties whereampliﬁcation of surface roughness can be inhibited. For a polymer material with Poisson’s ratio similar to poly~ethylene oxide! ,interfacial roughening is mechanically suppressed when the separator shear modulus is about twice that of lithium. © 2005 The Electrochemical Society. @DOI: 10.1149/1.1850854# All rights reserved.Manuscript submitted January 16, 2004; revised manuscript received July 29, 2004. Available electronically January 11, 2005.
Peculiarities of dislocation photoluminescence in germanium with quasi‐equilibrium dislocation structure

The dislocation photoluminescence (DPL) at 4.2 K was studied in germanium (Ge) single crystals of n- and p-type with quasi-equilibrium structure of 60° dislocations. The DPL spectra for different samples were decomposed on Gaussian lines (Gm-lines) over the range 0.47-0.58 eV characterized by practically the same peak energies Em and the widths under 15 meV. The G-lines with Em ≤ 0.55 eV were ascribed to the radiation of regular segments of 60° dislocations with different stacking fault (SF) widths Δ between 30 and 90° partials. An increase of the dislocations density up to ND ∼ 107 cm–2 was found to result in a considerable growth of the intensity of the G-lines with Em <0.513 eV. The factors, which promote the appearance of different Δ values for quasi-equilibrium 60° dislocation structure, are discussed. (© 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
Catadioptric Stereo Optical Gas Imaging System for Scene Flow Computation of Gas Structures

The need for reducing greenhouse gas emissions from industrial facilities has motivated the development of new and more reliable techniques for gas leak localization and quantification. Optical gas imaging (OGI) systems offer a fast and intuitive approach by exploiting the absorption properties of gases, such as methane, in the infrared range. Based on this, several efforts have been made in the recent years for gaining additional quantitative information from the measurement data, e.g. gas concentration or gas velocity. In this work, a catadioptric stereo OGI system based on four planar mirrors and an OGI camera is proposed for computing spatio-temporal (also referred to as scene flow) information from stereo gas images. The proposed system represents a way to reduce the effects of temporal and radiometric differences and the cost and size of two-camera-based stereo OGI systems and leads to more reliable results under the tested conditions.
A Consecutive Motion and Situation Recognition Mechanism to Detect a Vulnerable Condition Based on Android Smartphone

: Human motion recognition is essential for user-centric services such as surveillance-based security, elderly condition monitoring, exercise tracking, daily calories expend analysis, etc. It is typically based on the movement data analysis such as the acceleration and angular velocity of a target user. The existing motion recognition studies are only intended to measure the basic information (e.g., user’s stride, number of steps, speed) or to recognize single motion (e.g., sitting, running, walking). Thus, a new mechanism is required to identify the transition of single motions for assessing a user’s consecutive motion more accurately as well as recognizing the user’s body and surrounding situations arising from the motion. Thus, in this paper, we collect the human movement data through Android smartphones in real time for five targeting single motions and propose a mechanism to recognize a consecutive motion including transitions among various motions and an occurred situation, with the state transition model to check if a vulnerable (life-threatening) condition, especially for the elderly, has occurred or not. Through implementation and experiments, we demonstrate that the proposed mechanism recognizes a consecutive motion and a user’s situation accurately and quickly. As a result of the recognition experiment about mix sequence likened to daily motion, the proposed adoptive weighting method showed 4% (Holding time=15 sec), 88% (30 sec), 6.5% (60 sec) improvements compared to static method.
Theoretical Study of Open Chain Dimers and Trimers Containing CH3OH and H2O

Ab initio minimal basis LCAOSCF molecular orbital calculations have been performed on open chain dimers and trimers containing methanol and water. The equilibrium structures and energies of the dimers are determined and compared. The rigidity of the hydrogen bond in each dimer is discussed in terms of calculated intermolecular force constants. The energies of seven open chain trimers are presented and analyzed. It is found that the energies of all trimers deviate from additivity, indicating the existence of a cooperative effect in hydrogen bonding in these systems.
Circularly Polarized Luminescence and Circular Dichroism from Si−Si-Bonded Network Polymers

We demonstrated the first circularly polarized luminescence (CPL) and circular dichroism (CD) spectra of three new Si−Si-bonded network polymers bearing the chiral alkyl side groups poly[(S)-2-methylbutylsilyne] (1S), poly[(R)-3,7-dimethyloctylsilyne] (2R), poly[(S)-3,7-dimethyloctylsilyne] (2S), and, for comparison, poly(n-pentylsilyne), which bears an achiral alkyl side group (3). These polymers were successfully prepared by Na-mediated condensation of the corresponding alkyltrichlorosilanes with the help of crown ether. It was revealed that only 1S, which bears a β-branched chiral group, clearly showed an intense CPL signal at ∼570 nm with a quantum yield of ∼1%, along with its corresponding Cotton CD signals in tetrahydrofuran at room temperature. In contrast, 2R and 2S, which possess γ-branched chiral groups, did not show any CPL signal, though they did show the CD bands. As expected, 3 did not show CPL or CD signals. The β-branched chiral side chain was needed to provide the intense CPL band in the .
Efficiently Mitigating Transient Execution Attacks using the Unmapped Speculation Contract

Today’s kernels pay a performance penalty for mitigations— such as KPTI, retpoline, return stack stuffing, speculation barriers—to protect against transient execution side-channel attacks such as Meltdown [21] and Spectre [16]. To address this performance penalty, this paper articulates the unmapped speculation contract , an observation that memory that isn’t mapped in a page table cannot be leaked through transient execution. To demonstrate the value of this contract, the paper presents W ARD , a new kernel design that maintains a separate kernel page table for every process. This page table contains mappings for kernel memory that is safe to expose to that process. Because a process doesn’t map data of other processes, this design allows for many system calls to execute without any mitigation overhead. When a process needs access to sensitive data, W ARD switches to a kernel page table that provides access to all of memory and executes with all mitigations. An evaluation of the W ARD design implemented in the sv6 research kernel [8] shows that LEBench [24] can execute many system calls without mitigations. For some hardware generations, this results in performance improvement ranging from a few percent ( huge page fault ) to several factors ( getpid ), compared to a standard design with mitigations.
Attention, Recall and Purchase: Experimental Evidence on Online News and Advertising

We conduct an experiment where 1,000 individuals read online news articles and are shown ads for branded goods next to those articles. Using eye-tracking technology, we measure the attention that each individual devotes to reading each article and viewing each ad. Then, respondents choose between cash or vouchers for branded goods. We find that attention is a predictor both of willingness-to-pay for brands, and for brand recall. We also give suggestive evidence of the main drivers of attention. These include the type of news, and the match between individual political preferences and the media outlet.
The ordered structure of at 70 - 75 K

The ordered structure of at 70 - 75 K has been studied by time-resolved neutron powder diffraction. The ordered superlattice has a structure with approximately four full D sites and one vacant D site in successive (420) planes, which is consistent with previous observations. Several superlattice lines not reported in previous single-crystal studies were observed. Quantitative information about the ordered structure was obtained by careful Rietveld analysis of the data, including anisotropic line broadening and diffuse peak background corrections. The structure refinement confirms a relaxation of D atoms towards the vacant planes and reveals a related second-order displacement of the D atoms in the octahedral sites towards a preferred vacant nearest-neighbour site. The thermal vibration along the c-axis is anisotropic as a result of the preferential relaxation.
COVID-19 in Patients with CKD in New York City.

Background COVID-19 has affected millions of people, and several chronic medical conditions appear to increase the risk of severe COVID-19. However, our understanding of COVID-19 outcomes in patients with CKD remains limited. Methods This was a retrospective cohort study of patients with and without CKD consecutively admitted with COVID-19 to three affiliated hospitals in New York City. Pre-COVID-19 CKD diagnoses were identified by billing codes and verified by manual chart review. In-hospital mortality was compared between patients with and without underlying CKD. Logistic regression was used to adjust this analysis for confounders and to identify patient characteristics associated with mortality. Results We identified 280 patients with CKD, and 4098 patients without CKD hospitalized with COVID-19. The median age of the CKD group was 75 (65-84) years, and age of the non-CKD group 62 (48-75) years. Baseline (pre-COVID-19) serum creatinine in patients with CKD was 1.5 (1.2-2.2) mg/dl. In-hospital mortality was 30% in patients with CKD versus 20% in patients without CKD (P<0.001). The risk of in-hospital death in patients with CKD remained higher than in patients without CKD after adjustment for comorbidities (hypertension, diabetes mellitus, asthma, and chronic obstructive pulmonary disease), adjusted OR 1.4 (95% CI,1.1 to 1.9), P=0.01. When stratified by age, elderly patients with CKD (age >70 years) had higher mortality than their age-matched control patients without CKD. In patients with CKD, factors associated with in-hospital mortality were age (adjusted OR, 1.09 [95% CI, 1.06 to 1.12]), P<0.001, baseline and admission serum phosphorus (adjusted OR, 1.5 [95% CI, 1.03 to 2.1], P=0.03 and 1.4 [95% CI, 1.1 to 1.7], P=0.001), serum creatinine on admission >0.3 mg/dl above the baseline (adjusted OR 2.6 [95% CI, 1.2 to 5.4]P=0.01), and diagnosis of acute on chronic kidney injury during hospitalization (adjusted OR 4.6 [95% CI, 2.3 to 8.9], P<0.001). Conclusions CKD is an independent risk factor for COVID-19-associated in-hospital mortality in elderly patients. Acute-on-chronic kidney injury increases the odds of in-hospital mortality in patients with CKD hospitalized with COVID-19.