Miracle-dz/UniFAR-FTUs huggingface dataset:
Informed source extraction from a mixture of sources exploiting second order temporal structure

• A submitted manuscript is the version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers.
Protein Intake and Weight Loss inObese Men and Women withCardiometabolic Risk Factors

Protein Intake and Weight Loss in Obese Men and Women with Cardiometabolic Risk Factors Background Despite its popularity, increasing dietary protein appears to have modest effects on weight loss. Furthermore, the proportion of total energy from protein that facilitates weight loss in nutritionist-recommended moderately energy-restricted diets is not clarified. We studied the association between protein intake and weight loss in obese men and women with cardiometabolic risk factors.
EFFECT OF BETTER CONTROL OF HYPERTENSION ON LEFT VENTRICULAR MASS IN LONG TERM RENAL TRANSPLANT RECIPIENTS

Objective: Control of hypertension (HT) can lead to regression of left ventricular mass index (LVMI) especially in the first year of renal transplantation. However, effect of better control of blood pressure (BP) on regression of LVMI in long-term renal transplant recipients is not known. In this study, we aimed to determine whether improved control of HT would decrease LVMI in renal transplant recipients or not. Methods: Twenty-four nondiabetic renal transplant recipients were included in the final analysis. Patients were categorized into group A (controlled-HT) and group B (uncontrolled-HT) according to their daytime blood pressure levels at the beginning of the study. Antihypertensive drug treatment of patients in group B was modified according to ambulatory blood pressure monitorization (ABPM) and clinical measurements. Echocardiographic examination was performed at baseline and at the end of 24 month. Results: Systolic blood pressure (SBP) and diastolic blood pressure (DBP) declined significantly (p<0.01) in parallel to increased use of angiotensin converting enzyme inhibitor (p<0.01) and LVMI remained unchanged in group B (113 ± 34 g / m2 vs 112 ± 29 g / m2 at baseline and at the end of 24 month, respectively). Although SBP and DBP did not change significantly in group A, LVMI increased significantly (90 ±21 g / m2 to 107 ± 26 g / m2 at baseline and at the end of 24 month, respectively) in parallel to increase in serum creatinine (p<0.05) and decline in hemoglobin levels. Conclusions: Our results suggest that control of BP is not sufficient either for the regression or maintenance of LVMI in long term renal transplant recipients. However, factors such as low hemoglobin level and worsening of renal function may play critical roles in the progression of LVMI even in patients with well-controlled BP. Key Words: Renal transplantation, Left ventricular hypertrophy, Hypertension, Ambulatory blood pressure monitoring
A game based approach on eliminating computer energy waste

Energy reduction is one of the main challenges that countries around the world currently face. Two serious games were implemented with waste-oriented feedback, for the work environment (IdleWars) and for the home environment (EcoScreenCatcher). These games were competition oriented games designed to raise awareness of computer-based energy consumption. Both games deployed "in the wild" and were evaluated quantitatively and qualitatively. IdleWars is a pervasive and competition-oriented game. Workers' pro-environmental or wasteful behaviour is reflected in their game score, and displayed through eco-feedback visualisations. A two-week field deployment revealed that the physical and competitive elements of the game work well in engaging participants. The design was successful in catalysing and polarising existing social dynamics. Participants developed tactics and appropriated the game and extended its rules, sometimes in a way that favoured engagement and fun rather than conservation behaviour. EcoScreen- Catcher is a software-based competition-oriented game that calls attention to PC energy waste. Similarly to IdleWars, the human involvement in the feedback is an important design element. EcoScreenCatcher was deployed for over three weeks, with a total of 23 university students. Quantitative analysis showed that the game caused PC idle time reduction for players with four or more game friendships during the first week of playing. Post-study semi-structured interviews showed attitude changes and awareness of sustainability, as well as spill over effects to other appliances and to people who did not participate. To better understand the perception of waste in the home, interview analysis was undertaken of a study already conducted (and not part of this work) by the University of Southampton and by Kingston University. The analysis showed that the majority of participants' appliances being on when not in use as waste, as well as not using a resource to its full potential. Waste perception is in influenced by attributes such as comfort, cleanliness, culture, technological advancement, and age. Such a result shows that eco-feedback tools are not one-size-fits-all, and the human element combined with waste-oriented feedback has the potential to raise awareness and change behaviour.
Protocols of Dual Diagnosis Intervention in Schizophrenia

Objective:To review the existing literature on the psychopharmacological and psychotherapeutic treatment of patients with both schizophrenia and a substance use disorder (SUD). Methods:Selective review of the literature. PubMed search until November 2010. Results:Patients with psychotic disorders also frequently have SUDs. To attempt to explain their high coexistence there are different hypotheses, such as self-medication or the drug induction theories of chronic psychosis. Pathogenesis mechanisms are unknown. Patients may use substances to control or minimize symptoms such as hallucinations or anxiety, for the management of negative emotional states, to counteract negative symptoms and as a means of integration into a group. The diagnosis is complicated. It is important to correctly identify these patients because they have a more severe psychopathology, a more violent social behavior, and have more comorbidity with other medical diseases (such as human immunodeficiency virus or hepatitis C virus), which worsens the prognosis. The knowledge of the clinical characteristics and needs of these patients should enable suitable treatment programs to be developed. Conclusions:Substance abuse worsens the course and prognosis of schizophrenia and makes the psychopharmacological treatment and psychotherapeutic approach more difficult. Dual psychotics are characterized by low adherence to treatment and poor linkage to health facilities. Therefore, the integrated treatment model, in which the same therapeutic team jointly addresses schizophrenia and SUD, is offered as a therapeutic option of choice in managing these patients.
5-fluorouracile: données sur le métabolisme et place actuelle dans le traitement des cancers digestifs.

Thomas APARICIO, Michel DUCREUX, Stanislas CHAUSSADE (Gastroenterol Clin Biol 2002;26:38-47) 5-FLUOROURACIL METABOLISM • Anabolism • Catabolism • Pharmacokinetics • Pharmacokinetics modulation 5FLUOROURACIL TOXICITY MECHANISM OF RESISTANCE TO 5-FLUOROURACIL 5-FLUOROURACIL OPTIMIZATION • Chemical modulation • Schedule modulation • 5-FU combined with radiation therapy • Oral fluoropyrimidines CONCLUSION
Design and Implementation of the Spad Filesystem

Title: Design and Implementation of the Spad Filesystem Author: Mgr. Mikuláš Patočka email: mikulas@artax.karlin. mff.cuni. cz Department: Department of Software Engineering Faculty of Mathematics and Physics Charles University in Prague, Czech Republic Advisor: RNDr. Filip Zavoral, Ph.D. email: Filip.Zavoral@mff.cuni. cz Mailing address (advisor): Dept. of Software Engineering Charles University in Prague Malostranské nám. 25 118 00 Prague, Czech Republic WWW: http://artax.karlin. mff.cuni. cz/~mikulas/spadfs/
Procura de Cuidados e Acesso aos Serviços de Saúde em Comunidades Imigrantes: Um estudo com imigrantes e profissionais de saúde

This study aimed to describe the perceptions of immigrants and health professionals regarding health care seeking and the factors that influence access and utilization of health services among immigrants. data was collected through focus groups with intentional samples of 20 immigrants and 32 health professionals. Six focus groups were conducted, one with each immigrant group (from Portuguese-speaking African countries, Brazil and Eastern European countries) and health professional group (doctors, nurses, office workers). data were analyzed using content analysis. The results revealed the existence of different patterns of health care seeking, having been described situations of regular utilization of health services, use only in an acute condition and non-utilization. Simultaneously, given the need of health care, other practices were reported. In focus groups, some barriers in access and utilization of health services were pointed out, as the irregular status, the socioeconomic difficulties, the lack of knowledge on legislation about access, the cultural issues, the attitudes and competencies of professionals and those related with services. The seeking of health care at the health services results from the dynamic interaction of multiple factors that should be taken into account in the planning of strategies for improving health of immigrant populations. Access to health care involves several aspects besides the legal right. It is essential to invest in health professionals’ training concerning their knowledge and competencies to deal with cultural diversity, and in provision of information about the health services and rights among immigrant populations.
Limb salvage alternatives for primary bone sarcomas in children

Surgeries for bone sarcomas demand two attentions: resection (wide margins, lower risk of recurrence) and reconstruction (complications, failures, infection). After wide resection for bone sarcomas, limb reconstruction can be performed with biological or nonbiological methods. Sarcoma surgery is complex, requiring a large variety of patterns. The surgeon must choose the best technique individually for each patient. We reviewed recent advances in limb salvage and reconstruction for osteosarcoma in children.
Knee injuries in the youth athlete

As community-based, organized youth sports have increased in popularity over the last several years, so has the rise of pediatric orthopaedic sports medicine as a subsubspecialty. Although nonsurgical fractures and overuse injuries are seen most commonly, the incidence of surgical injuries, particularly about the knee, is on the rise. This article will review and synthesize recent advances in the treatment of knee disorders resulting from youth sports participation. Surgically treated tibial spine fractures result in low rates of residual instability, but postoperative arthrofibrosis continues to be a problem. Further meniscal injury with nonsurgical treatment of anterior cruciate ligament rupture is likely, and repair of meniscal tears during anterior cruciate ligament reconstruction may be more successful than in adults, even with “marginally reparable” tears. Evidence suggests that transepiphyseal, extraphyseal, and transphyseal reconstruction with soft-tissue graft and extraphyseal fixation all can be performed safely, even in prepubescent patients, although mild residual clinical laxity often results. Symptomatic discoid meniscal tears are increasingly treated with repair of peripheral rim instability while preserving maximal meniscal tissue. Stable juvenile (compared with adult) osteochondritis dissecans lesions have increased healing potential with nonsurgical treatment, although assessing stability with MRI is more difficult than in adults. Finally, although medial patellofemoral ligament reconstruction for patellar instability is increasingly performed in the skeletally mature, there are physeal anatomical considerations in the immature, and outcome studies of physeal sparing techniques are better documented in the literature. Newer surgical techniques for treatment of knee injuries in youth athletes may offer more successful return to play with decreased incidence of complications such as stiffness and growth arrest.
Review on a new austenitic 57Fe15Cr25Ni stainless steel at temperature of 850C for 30 minutes followed by water quenching treatments

Special steel demand is indispensable in nuclear field, especially as a construction material for structure of high temperature reactor. An austenite 57Fe15Cr25Ni stainless steel has been synthesized by using casting technique at temperature more than 1250°C in electromagnetic inductive-thermal furnace. The steel comprised of (%wt) 57%Fe, 15%Cr, 25%Ni, 0.34%C and less than 0.1% of other elements: titanium, phosphor, copper, niobium and sulphur. It is due to promoted for a high pressure-temperature operating system, the material must have strength, creep and corrosion resistances. To increase the strength of the material, heat treatment is needed in certain cooling media, i.e. water. As suspected to that of temperature selection of 850°C, that ferritic phase contributes to the strength of steel. The hardness of material increases up to 18% after being cooled rapidly into water medium. Even in the diffraction pattern, the ferritic phases do not grow clearly due to probably small amount of fraction. X-ray diffraction pattern just shows that ascast with an fcc’s lattice parameter of about 3.69 A. Meanwhile, the water quenched sample has a lattice parameter which is slightly shorter than that ascast¢s lattice parameter, i.e. 3.59A. The peak shift of the (111) plane in the profile diffraction, is shown approximately 0.079 degrees between ascast and water quenched samples, indicates the presence of residual strain that threatens the structural stability of the material. The ascast microstructure shows that austenite phase grains look very massive and illustrate irregular structures, with an average grain size of about 6-8 µm, showing coarse grains that are very different from the water quenched microstructure shown by fine grains and slightly porous. On the other hand, the viscosity ( h ) of quenching media has a very significant role in grain boundary formation (sensitization), because the rate of temperature drop is strongly influenced by heat diffusion from high to low temperature spaces at the surface of material. Moreover, there were no new phase formation and fatal scales in the corrosion appearance of the steel surface at 850°C after more than 15 hours of oxidation tests. Therefore, at temperatures 850°C, the steel is proven to withstand of its high temperature environmental corrosion.
A STUDY TO INVESTIGATE THE QUALITY OF EDUCATION AT INTERMEDIATE LEVEL IN PUNJAB

Education is a powerful instrument of socio-economic and political change concomitant to global, technological and democratic developments. So it is necessary to improve quality of education at different levels of education. Intermediate Level of education is the most crucial stage of entire system of education. It holds a key position and is the terminal stage for majority of students. The large number of educated manpower in Pakistan is available at this stage. Improvement of quality of this stage is essential for futuristic development, which is directly related to the quality of teachers, students and the support services provided to them by the educational institutions. The major purpose of the study was to investigate the Quality of Education at Intermediate Level in Punjab. Which now forms part of secondary education and is commonly known as higher secondary education. The main objectives of the studies were (1) To find out the adequacy of educational facilities available for teaching at Intermediate Level. (2) To explore the quality of Curricula at Intermediate Level. (3) To determine the suitability of medium of Instruction at Intermediate Level. (4) To examine the appropriateness of In-service training provided to the teachers at Intermediate Level. (5) To make some workable recommendations for the improvement of quality education at Intermediate Level. All the Degree Colleges, all the Intermediate Colleges and all the Higher Secondary Schools were constitutes the population, all the heads, all the teachers and students of these institutions were also included in the population. A random sampling technique was used for selection of the sample. Forty Degree Colleges (twenty male, twenty female), forty Intermediate Colleges (twenty male, twenty female) and forty Higher Secondary Schools (twenty male, twenty female) were included in the sample. The principals of one hundred and twenty institutions, six hundred teachers, and twelve hundred students were also included in the sample. Three questionnaires (one each for principals, teachers and students) were administered to the sample principals, teachers and students to get data. Collected data were tabulated, analyzed and interpreted in the light of objectives of the study by applying statistical tools of research such as mean, standard deviation, standard error of mean and estimated population mean. In the light of the conclusions it is recommended that audio-visual aids should be provided to the institutions, teachers be provided training and be motivated to use these A. V. aids to make the teaching learning process effective. Resources play a very prominent role in generating quality. For this purpose it is recommended that allocating sufficient budget for education and by improving the pay scales of the teachers quality should be enhanced. Infra structure also affects quality of education, it is recommended that proper physical facilities should be provided to the institutions for quality education.
2-(2,4-Dichlorophenyl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide

In the crystal structure of the title compound, C19H17Cl2N3O2, the molecules form dimers of the R 2 2(10) type through N—H⋯O hydrogen bonding. As a result of steric repulsion, the amide group is rotated with respect to both the dichlorophenyl and 2,3-dihydro-1H-pyrazol-4-yl rings, making dihedral angles of 80.70 (13) and 64.82 (12)°, respectively. The dihedral angle between the dichlorophenyl and 2,3-dihydro-1H-pyrazol-4-yl rings is 48.45 (5)° while that between the 2,3-dihydro-1H-pyrazol-4-yl and phenyl rings is 56.33 (6)°.
“Liking” Social Networking Sites – Use of Facebook as a Recruitment Tool in an Outbreak Investigation, The Netherlands, 2012

Social Networking Sites (SNSs) such as Facebook offer health researchers a novel means to reach and engage with the public. Following a mumps outbreak in a Dutch village after a Youth Club party organised via the Facebook Events facility, we used Facebook to recruit attendees to our outbreak investigation. After a poor response using traditional means of publicising the study, we opened a Facebook account under the study name, sent private messages about the study to all individuals invited to the party via the Facebook Event, and regularly posted the questionnaire web-link to the online notice boards (“Wall”) on the Youth Club and our own Facebook accounts. We concurrently incentivised participation using gift vouchers but only directly informed individuals who had responded “Yes” to the Event of the incentive. Participant numbers subsequently increased from ten to 60 (response ~60%). 80% of participants reported hearing about the study via Facebook. Although impossible to disentangle the effects of the active Facebook protocol and the incentive, Facebook offered a means of directly contacting attendees whilst avoiding advertising the incentive to non-attendees. SNSs can potentially make an important contribution to modern health research, and ethical codes of conduct should be updated to encompass their use.
Deep Vein Thrombosis after Coronary Angiography

Deep vein thrombosis (DVT) is a rare but potentially serious complication of coronary angiography (CAG), incidence being just 0.05%. Only a few clinical cases of DVT after diagnostic transfemoral catheterization have been reported. Here, we describe the case of a 54-year-old woman who developed significant DVT after CAG without venous thromboembolism (VTE) and, which was treated with anticoagulants.
Comparative Regulatory Effects of Morus Alba Leaf Extracts on HepaticEnzymes in Streptozotocin-Induced Diabetic and Non-Diabetic Rats

Aim and objectives: Diabetes is a metabolic disorder with hyperglycemia due to defects in insulin secretion and function. Several studies investigated the both effects of traditional herbal medicine in diabetes treatment. Therefore, the aim of the present study was to investigate the effects of Morus Alba leaf Extracts (MAE) on hepatic enzyme activity in normal and streptozotocin-induced diabetic rats. Methods: Forty healthy adult male Wistar rats weighing 250 ± 10 gr were taken for this experiment. Rats were divided into 4 groups (10 rats in each group). Animals treated by a gavage tube for a period of two months as follow: group I: non diabetic control rats which only received distilled water; group II: non-diabetic rats that received (MAE) 1.0 g/kg per day; group III: diabetic control rats treated with distilled water and group IV: Diabetic rats which received MAE 1.0 g/kg per day. At the end of the 8th week, blood samples were collected and serum levels of enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), and total bilirubin were measured in all study groups using commercial assay kits. The activity of two antioxidant enzymes including glutathione peroxidase (GPX) and glutathione reductase (GR) were also measured. Results: Findings of present study demonstrated that MAE significantly decreased serum levels of liver enzymes ALT, AST and ALP in diabetic rats in compare to the diabetic control groups while it increased GPX and GR activity(P<0.05). These results also indicated that MAE did not significantly affect LDH activity in diabetic rats treated with MAE in compared to the diabetic control groups. Conclusions: According to the present findings it could possibility be suggested that the anti-hyperglycemic effect of MAE is mediated at least partially by increasing liver GPX and GR activity as well as decrease serum levels of liver enzymes ALT, AST and ALP. These results are the other definite evidence supporting MA as traditional medicine for diabetic patients.