Miracle-dz/UniFAR-FTUs huggingface dataset:
Exact strip analysis and experiments on buckling and post-buckling of plates and stiffened panels with mode jumping

Engineering components consisting of plated structures subjected to in plane loading can potentially fail due to buckling. This work focuses on presenting novel approaches to enhance the buckling and post-buckling behaviour of flat plates and stiffened panels made with metal and composite materials under in-plane loading conditions. A better understanding of post-buckling behaviour, including the phenomenon of mode jumping, will lead to improvements in both design criteria and manufacturing processes. The first part of this thesis describes an extensive study using the exact finite strip computer program VICONOPT and the finite element method to investigate the buckling of simply supported composite plates under different in plane loads. This approach utilises the lamination parameters to enhance the buckling capacity through the anisotropic properties of the laminate. Numerical relationships are presented as an optimisation procedure to maximise the buckling load under in plane uniaxial compression, shear or a combination of both. The procedure is applied to a series of anisotropic symmetric and balanced laminates with varying thickness and aspect ratios. The second part presents a numerical and experimental study to explore the post-buckling phenomenon of mode jumping phenomenon in plates and stiffened panels. The VICONOPT post-buckling analysis is extended to predict mode jumping, and the resulting numerical investigations are validated by finite element analysis. Furthermore, a series of experimental tests have been devised to investigate the buckling, post-buckling and mode jumping behaviour of curved stiffened panels with different radii of curvature. The experimental results are compared with finite element results in order to examine the similarities and differences between simulations and real behaviour of panels under compressive load.
Disease Severity and Common Etiology of Diarrhea among Children Under-five in Mirzapur, Rural Bangladesh

Aim: There is lack of information on the severity of diarrheal disease with etiology. Thus the study aimed to compare the etiology of under-five children with moderate-to-severe disease (MSD) and mild disease (MD). Study Design: Diarrheal disease surveillance. Place and Duration of Study: Mirzapur Kumudini Hospital, Tangail, rural Bangladesh, January 2010 – December 2011. Methodology: Overall, 2,324 under-5 diarrhea children were enrolled in the hospital who Research Article International Journal of TROPICAL DISEASE & Health, 3(2): 82-93, 2013 83 came from the demographic surveillance system (DSS) catchment area. Whole stool samples were collected from each enrolled child to detect rotavirus, Shigella, ETEC and V. cholerae. Information on socio-demographic and clinical characteristics was also collected. Results: Among all the study children, 1,098 (47%) were aged 0-11 months; 789 (34%) were 12-23 months, and 437 (19%) were 24-59 months. Rotavirus (33%) was mainly responsible for diarrhea amongst children under-5 and 90% of them were less than 2 years. Shigella represented 14%; of which, 45% were 24-59 months old. However, ETEC and V. cholerae represented only 3% and 2% respectively. Shigella was the most commonly detected pathogen (27%) for MSD followed by rotavirus (16%). Conversely, rotavirus (43%) was responsible for MD. MSD were most likely to be infected with Shigella flexneri [OR-9.81; 95% CI (6.38, 15.18)] and Shigella sonnei [6.29; (3.67, 10.87)] compared to their counterparts with MD. In logistic regression analysis, Shigella was responsible for a 2.25 times higher risk for MSD. Children with Shigella were 3.28 times at higher risk for bloody stool and 2.45 times more likely to have fever. However, rotavirus diarrhea was more likely to be presented with vomiting (OR-2.46) and fever (OR-1.28), and Vibrio cholerae, most often with watery diarrhea (OR-4.35). None of the clinical features were significantly associated with ETEC. Conclusion: Shigella was the leading pathogen that was detected most often in MSD, whereas rotavirus was often associated with MD.
Pharmacokinetics of irbesartan are not altered in special populations.

Summary:Studies were conducted to determine whether pharmacokinetics of irbesartan (IRBE), a potent, long-acting angiotensin (AT)-II receptor antagonist selective for AT-II type 1 receptor subtype, are altered in patients with renal impairment (RI), hepatic impairment (HI), or heart failure (HF) or
What Brainstem Recordings May or May Not Be Able to Tell Us about Hearing Aid–Amplified Signals

Abstract Performance variability among people who wear hearing aids presents a challenge for clinicians. Although some clients appear to make use of amplified signals with little effort, other clients report frustration and may reject their hearing aids altogether. Some of the explanations underlying performance variability likely result from a poorly fitted device; others might result from reasons related to how the amplified signal is being represented in the central auditory system. We believe that perception is dependent on the neural detection, representation, and integration of the amplified speech and noise. For this reason it is important to understand how amplification modifies the acoustic content of a signal as well as the neural representation of the amplified sound. It is therefore necessary to examine the interaction between hearing aid–processed acoustic input and the neural networks that are activated. Here we focus on the role of brainstem encoding to determine if auditory brainstem responses might provide information to help explain why some people are able to make better use of amplified sound than others. More specifically, we review the literature to determine if brainstem measures might someday be used to guide clinicians when fitting a hearing aid.
Deep neural network based pier scour modeling

ABSTRACT Advancement in computing power over last decades, deep neural networks (DNNs), consisting of two or more hidden layers with large number of nodes, are being suggested as an alternate to commonly used back-propagation neural networks (BPNN). DNN are found to be flexible models with a very large number of parameters, thus making them capable of modeling complex and highly nonlinear relationships. This paper investigates the potential of a DNN to predict the local scour around bridge piers using field dataset. To update the weights and bias of DNN, an adaptive learning rate optimization algorithm was used. The dataset consists of 232 pier scour measurements, out of which a total of 154 data were used to train whereas remaining 78 data to test the created model. A correlation coefficient value of 0.962 (root mean square error = 0.296 m) was achieved by DNN in comparison to 0.937 (0.390 m) by BPNN, indicating an improved performance by DNN for scour depth perdition. Encouraging performance in present work suggests the need of further studies on the use of DNN for various applications related to water resource engineering as an alternate to much used BPNN.
A Patient With Glioblastoma Who Died From Lung and Pleural Lesions With Rapid Progression: Synchronous Double Primary Malignant Tumors

A 64-year-old man with a right temporal lobe glioblastoma (GB) received surgical treatment followed by radiotherapy plus concomitant daily temozolomide (75 mg/m2 of body-surface area). He was readmitted, because lung and pleural lesions were detected on chest x-ray and computed tomography. Simultaneous recurrence of GB was also found on head magnetic resonance imaging. He underwent a second craniotomy for resection of the recurrent GB with biopsy of the pleural mass at the same time. After the reoperation, chest computed tomography revealed rapid progression of the lung and pleural lesions, with no evidence of GB recurrence on head magnetic resonance imaging. One month after the second craniotomy, the patient died from respiratory compromise related to infiltrating lung and pleural lesions. The brain and pleural lesions showed marked differences in hematoxylin and eosin staining and immunohistochemistry staining. Because the 2 lesions were distinctly different in pathology, we presumed that they occurred incidentally at the same time, as synchronous double primary malignant tumors. We report on a patient with a rare case of GB who died from lung and pleural lesions with rapid progression, despite stable intracranial lesion.
Orbital energy analysis with respect to LDA and self-interaction corrected exchange-only potentials

The self-interaction correction of Perdew and Zunger with the optimized effective potential using the Krieger–Li–Iafrate approximation is analyzed for atomic and molecular systems in the exchange-only context. Including the self-interaction correction (SIC) orbital by orbital shows that the appropriate asymptotic behavior of the exchange potential can be achieved if just the contribution of the highest occupied molecular orbital (HOMO) is considered. However, if a good description of the exchange potential in the valence region is required, and consequently a good description of the HOMO energy, then all electrons of the valence shell must be taken into account. In contrast, the lowest unoccupied molecular orbital (LUMO) is described adequately if just the HOMO SIC contribution is employed. In addition, if the lowest occupied orbital is also considered in the SIC approximation, there is an improvement in the description of the exchange potential in inner regions of an atom. When all electrons in an atom o.
Evaluation of Structural Stability by Characterization of Lateritic Soils with Rock Flour along Ibadan-Iwo-Osogbo Highway, Southwestern Nigeria

Failures of different categories of roads shortly after being opened to traffic have necessitated the need for sustainable alternative road building materials. This study determines the potential of rock flour on the geotechnical properties of lateritic soils with a view to establish the optimum content of the rock flour required for effective stabilization and proffer lasting remediation measures to the incessant road failures. Ten bulk lateritic soil samples were collected from ten trial pits at depths of 1.5 m in different locations of the study area. Index and engineering property tests were performed on the soils, both in their natural and stabilized states by adding 2, 4, 6, 8 and 10% rock flour contents. In addition, CBR – UCS model was used to establish a third order polynomial to correlate the soil-rock flour mix. The results show that the plasticity and linear shrinkage of the soils decreased with increase in rock flour contents. The MDD of rock flour stabilized soils increase with the maximum improvement observed at 10% by weight of rock flour with the corresponding decrease in OMC. The load bearing capacities (LBC) of the soils increase with the stabilization mix. It was observed that the values meet the requirements for good quality subgrade, subbase materials and some of the soils for base materials in road construction. The results also reveal the improvement of the soil properties. This is further confirmed by the increase in UCS and shear strength of the soils which optimally improved on addition of 8% rock flour. Moreover, the addition of more than 8% by weight of rock flour caused reduction in UCS and shear strength. These results show the stabilizing potentials of rock flour on lateritic soils especially when added at the optimum level. The CBR - UCS models established are in form of third order polynomial (ax3- bx2 + cx +d) with the R2 values, 0.672 and 0.528 which indicate positive correlation of the soil-rock flour mix. Therefore, rock flour can potentially stabilize lateritic soils solely with addition of 8% recommended as an optimum content for stabilizing lateritic soils for road constructions.
Determination of Winter Trekking Routes Within the Scope of Winter Tourism Potential in Sivas Province

Article Type: Conceptual Paper The investments made for the development and diversification of tourism in Turkey in terms of winter tourism in order to increase the income derived accordingly has gained momentum in recent years. In this respect, the recent activation of Sivas Yıldız Mountain Winter Sports Center has made Sivas a center of attraction in terms of winter tourism. However, the tourism attraction of Sivas will increase further with the introduction of different recreational and sporting activities for winter tourism within the scope of tourism diversification. Spreading on high plateaus, Sivas province is known for its freezing temperatures in winter and its nature which is snow-covered for a long time. The basis of this study is the evaluation of these features within the scope of winter tourism and the determination of winter trekking routes that could be a different activity for tourists in terms of recreation. As the primary data for the research, a field study was carried out by make interviews with the administrators of Sivas Alpin Nature and Youth Sports Club. Secondary data were obtained by searching literature on winter tourism, recreation and sports. Winter hiking routes with different difficulty levels that can be enjoyed throughout the winter season in Sivas have been determined in view of the findings obtained from the study. Various evaluations and suggestions have been made for the promotion and development of these routes. The aim is that all stakeholders, especially regional decision-makers (governorships, district governorships, municipalities, universities and NGOs) benefit from this study.
Saturn's Plasmapause: Signature of Magnetospheric Dynamics

We explore the paradigm that Saturn's plasmapause marks the boundary between the magnetic flux tubes that have been circulating around the planet for some time, accumulating a dense load of Enceladus‐sourced material, and those that have recently undergone tail reconnection, shedding the bulk of the cold plasma and retaining a more tenuous, heated population. A centrifugally driven interchange instability should develop at this boundary, producing fingers of outward propagating dense plasma and of inward propagating hot, tenuous plasma. The plasmapause should thus be identifiable as a transition from mostly‐dense‐with‐some‐tenuous to mostly‐tenuous‐with‐some‐dense plasma populations. Electron densities from the Cassini Plasma Spectrometer/Electron Spectrometer (CAPS/ELS) instrument are used to identify the location of this transition for all of the low‐latitude (<5° from the magnetic equator) passes through Saturn's inner/middle magnetosphere. The boundary is typically found near and somewhat beyond L=10 (i.e., at ~10 Rs from the planet), with a local time asymmetry such that it is closer to the planet on the night side than on the day side.
G‐CLASS: geosynchronous radar for water cycle science – orbit selection and system design

The mission geosynchronous – continental land atmosphere sensing system (G-CLASS) is designed to study the diurnal water cycle, using geosynchronous radar. Although the water cycle is vital to human society, processes on timescales less than a day are very poorly observed from space. G-CLASS, using C-band geosynchronous radar, could transform this. Its science objectives address intense storms and high resolution weather prediction, and significant diurnal processes such as snow melt and soil moisture change, with societal impacts including agriculture, water resource management, flooding, and landslides. Secondary objectives relate to ground motion observations for earthquake, volcano, and subsidence monitoring. The orbit chosen for G-CLASS is designed to avoid the geosynchronous protected region and enables integration times of minutes to an hour to achieve resolutions down to ∼20 m. Geosynchronous orbit (GEO) enables high temporal resolution imaging (up to several images per hour), rapid response, and very flexible imaging modes which can provide much improved coverage at low latitudes. The G-CLASS system design is based on a standard small geosynchronous satellite and meets the requirements of ESA's Earth Explorer 10 call.
Disturbance after Disturbance: Combined Effects of Two Successive Hurricanes on Forest Community Structure

Our attempts to gain knowledge from studying the effects of a single windstorm might be complicated by one or more other events that pass through the same system before it recovers from prior damage. In this article, we had the opportunity to examine permanent plots affected by two consecutive catastrophic storms of comparable intensity within a short time frame (less than a decade). We compared tree damage patterns resulting from Hurricane Rita in 2005 and Hurricane Ike in 2008, which struck the same five forest plots (40 m × 50 m each; 1 ha total) established in the Big Thicket National Preserve of southeast Texas. The results showed that the post-Rita forest structure was characterized by intense damage to short, shade-tolerant stems and increased canopy openness. Hence, trees damaged by Ike were, in general, taller, more shade intolerant, and more spatially distant from their undamaged counterparts than trees damaged by Rita. These contrasting damage patterns indicate that Ike affected the plots differently to a normal windstorm occurring in isolation (after a long absence of prior windstorms). We anticipate that the cumulative, compounded effects of these two storms will potentially have long-lasting footprints on the structure and function of the study forest. The need to account for compounding disturbance interactions in forest research and management will grow, because many atmospheric scientists predict increases in both the intensity and frequency of hurricanes in conjunction with future climate change scenarios. Key Words: Big Thicket, disturbance interaction, forest structure, hurricane, spatial point pattern analysis.
Assessment of Particulate Matter (PM2.5) in Residential Staff Quarters of Covenant University, Nigeria

Over the years, the quality of outdoor air has received more attention than indoor air quality because people generally assume that only ambient air is polluted. Studies have shown that humans spend 70-80% of their time indoors, ranging from workplaces to homes. Based on the findings of these studies, outdoor exposure measurement is insufficient to estimate the total exposure of humans to particulate matter, PM2.5 pollution. The increasing interest of researchers and international bodies in indoor air quality evidenced in the study of different indoor pollutants, placing PM at the forefront. The air quality in the residential staff quarters of Covenant University was examined by taking continuous measurements from the indoor environment for three (3) days using standard sampling and analytical methods Air Ae Steward, an air quality monitoring device. The concentrations of PM2.5 in eleven (11) residential apartments were determined. The results indicate substantial indoor levels of PM2.5 with the highest and least mean values of 91.0±5.0 and 34.0±4.0 µg/m3 respectively.PM2.5 indoor concentration was found to be higher than the World Health Organisation guideline value of 25 µg/m3.Considering that inhabitants of these facilities spend more time indoors, appropriate ventilation systems would reduce health related risksassociated with PM2.5.
Coaching Considerations for the Tire Flip

THE PURPOSE OF THIS COLUMN IS TO PROVIDE A BASIC RECOMMENDATION TO INTEGRATING AND APPLYING THE TIRE FLIP EXERCISE TO THE STRENGTH AND CONDITIONING PROGRAM. IT WILL LOOK AT FACTORS SUCH AS SELECTING A TIRE, PERFORMING THE EXERCISE CORRECTLY, COMMON TECHNICAL FLAWS, AND HOW TO SPOT THE EXERCISE.
Original paper The effect of superficial femoral artery stenting and some atherosclerosis risk factors on changes in selected global endothelial function tests in patients with chronic lower limb ischemia. A pilot study

Introduction: Endothelial dysfunction is the main pathomechanism of atherosclerotic processes and their complications. Revascularization and control of atherosclerosis risk factors may improve the global endothelial function. Aim: Assessment of the relationships between the level of selected atherosclerosis risk factors and changes in noninvasive endothelial function parameters during one year long follow-up after superficial femoral artery (SFA) stenting. Material and methods: Seventeen male patients after SFA stenting were studied. Before the endovascular procedure, one day after it, and after 1, 3, 6, and 12 months after SFA stenting the values of global endothelial function parameters were evaluated, as follows: ankle-brachial index (ABI), flow-mediated brachial artery dilatation, distensibility coefficient, and Doppler parameters of blood flow in brachial and common carotid arteries in response to brachial ischemia and nitroglycerin sublingual application as well as in tima-media complex thickness. Results: Of the studied parameters only ABI improved significantly after SFA stenting. The changes in values of investigated endothelial function parameters were related to presence of atherosclerotic risk factors, such as age above 62 years, hypercholesterolemia, diabetes, and hypertension. Generally, global endothelial function tests were worse in patients with these conditions before the endovascular procedure, then they improved to reach the level observed in individuals without cardiovascular risk factors already after 3 to 6 months after SFA stenting. Conclusions: The SFA stenting together with adequate pharmacotherapy may reduce the negative effect of comorbidities on the global endothelial function and vasodilatation reserve of brachial and carotid arteries.
Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir

Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation/medication use evaluation (DUE/MUE) is also provided each month. With a subscription, the monographs are sent in print and are also available on-line. Monographs can be customized to meet the needs of a facility. A drug class review is now published monthly with The Formulary Monograph Service. Through the cooperation of The Formulary, Hospital Pharmacy publishes selected reviews in this column. For more information about The Formulary Monograph Service, call The Formulary at 800-322-4349. The May 2015 monograph topics are palbociclib, lenvatinib, nivolumab, ferric pyrophosphate citrate solution, and secukinumab. The Safety MUE is on non-opioid injectable pain or fever medications.