Miracle-dz/UniFAR-FTUs huggingface dataset:
Risque de récidive après un premier épisode de maladie veineuse thromboembolique chez la femme jeune : étude de cohorte

La contraception oestroprogestative (COP) est l'un des facteurs de risque les plus frequents de maladie veineuse thromboembolique (MVTE) chez les femmes jeunes. Cependant, le risque de recidive apres une MVTE survenue sous COP est mal connu. Notre objectif etait de determiner le risque de recidive d'un premier episode thromboembolique veineux chez la femme jeune, en fonction du contexte hormonal initial, des facteurs de risque initiaux, et de l'exposition a des circonstances a risque au cours du suivi. De 1992 a 2011 toutes les patientes de notre centre, âgees de 18 a 50 ans, presentant une MVTE confirmee survenue sous COP ont ete incluses consecutivement. Nous avons inclus 235 femmes, avec un suivi median de 67 mois apres l'arret de l'anticoagulation initiale. L'incidence annuelle des recidives est de 11,76 pour 1000 femmes-annee chez les femmes utilisatrices de contraception oestroprogestative lors de l'evenement initial et de 12,84 pour 1000 femmes -annee dans le groupe de femmes sans COP. Il n'y avait pas de difference entre les deux groupes meme lorsque l'analyse etait restreinte aux evenements majeurs idiopathiques. Ce taux de recidive est faible par rapport au risque global apres MVTE, comparable au risque observe apres un evenement provoque dans une population de femmes jeunes. Pendant le suivi, la grossesse et le post-partum etaient des circonstances a risque de recidive soit 50% des recidives, la MVTE survenant soit en debut de grossesse avant le debut de la prophylaxie, soit en post-partum apres l'arret des anticoagulants mais aussi sous prophylaxie bien conduite.
Partnership and co-operation between the teacher education institute and the schools: a precondition for structured learning from practice in school-based programmes

This paper describes a school-oriented teacher education program at the Institute of Education, University of Utrecht (Netherlands). The program prepares teachers for the upper level of secondary education in a one-year post-graduate course that follows a four-year subject matter masters program. Because half of the one-year course is school-based, an intensive partnership is required between the university and the school. There is also need for careful consideration of the relationship between theory and practice and close collaboration between teacher-educators and cooperating teachers. This collaboration is based on research into the gap between theory and practice, resulting in a structured approach to the student teachers learning processes that encourages reflection on practice. The preservice year is designed to integrate these experiences. The preservice teacher spends 250 hours in the classroom, including a minimum of 120 hours of instruction by the preservice teacher. The year is divided into the following periods: introduction (2 weeks), triad teaching practice (14 weeks), reorientation (10 weeks), individual and independent final teaching (14 weeks), and concluding phase (3 weeks). (Contains 42 references.)
Which components of heart failure programmes are effective? A systematic review and meta‐analysis of the outcomes of structured telephone support or telemonitoring as the primary component of chronic heart failure management in 8323 patients: Abridged Cochrane Review

Telemonitoring (TM) and structured telephone support (STS) have the potential to deliver specialized management to more patients with chronic heart failure (CHF), but their efficacy is still to be proven. The aim of this meta‐analysis was to review randomized controlled trials (RCTs) of TM or STS for all‐cause mortality and all‐cause and CHF‐related hospitalizations in patients with CHF, as a non‐invasive remote model of a specialized disease‐management intervention.
The conspicuity of pedestrians at night: a review

Drivers' visual limitations are a leading contributor to night‐time traffic crashes involving pedestrians. This paper reviews the basic changes in vision that occur at night for young and old visually healthy drivers, as well as those with common ocular pathology. To maximise their safety at night, pedestrians should be conspicuous. That is, beyond being simply visible (detectable as an ambiguous object), they should attract the attention of drivers and be readily perceivable as pedestrians. Research has established that the conspicuity of pedestrians can be optimised by attaching retroreflective markings to the pedestrian's extremities. Doing so highlights the pedestrian's ‘biological motion,’ which facilitates the accurate perception of a person; however, retroreflective markings on the torso (for example, vests) are less effective. Importantly, behavioural evidence indicates that most road users – drivers and pedestrians alike – are not aware of the limitations of night vision. For example, drivers typically ‘overdrive’ the useful range of their headlight beams and under‐use their high beam headlight setting. Further, pedestrians overestimate their own conspicuity at night and fail to appreciate the extent to which their own conspicuity depends on their clothing. The widespread misunderstanding of the challenges associated with night driving reflects a lack of awareness of the fundamental limitations of night vision. Educational interventions are needed to ameliorate these dangerous misunderstandings and to improve the safety of all road users at night.
Ungas psykiska hälsa i Sverige - komplexa trender och stora kunskapsluckor

De resultat som redovisas ligger i linje med tidigare studier som visar att den sjalvskattade psykiska ohalsan i ett langre tidsperspektiv har okat bland ungdomar i 15-arsaldern och uppat, framfor .
Lower extremity movements in frontal plane balance control during one-leg stance

textabstractA major turning point in human phylogenetic development occurred with the transition of Hominidae (anthropoid humans) from four-leg stance to two-leg stance. There are two different theories about the cause as well as the time of this transition. A widely adopted view is that the transition from four-leg stance to two-leg stance occurred about 3.5 million years ago when, as the result of the increased brain mass, the capacity for the construction and utilization of tools for hunting and food preparation was obtained. In the absence of fossils to support tlus theory, an alternative view was developed according to which the transition occurred much earlier, about 10 million years ago, due to the altered social and behavioral patterns(l), Whatever the cause of its initiation, the adoption of biped stance and locomotion must have had distinct advantages over quadruped stance for the survival of these early humanoids.
Summary of recommendations from the Canadian Asthma Consensus Report, 1999

Under the leadership of the Asthma Committee of the Canadian Thoracic Society, a group of respirologists, pediatricians, immunoallergists and emergency and family physicians met at Niagara-on-the-Lake, Ont. , from 28 to 31 May 1998, to review Canadian recommendations for the best management of asthma
Usefulness of immunocytochemistry using a Breast Marker antibody cocktail targeting P63/cytokeratin7/18/cytokeratin5/14 for fine needle aspiration of the breast: a retrospective cohort study of 139 cases

The Breast Marker Cocktail from Biocare Medical comprises five antibodies recognising p63, and cytokeratins (CKs) 7, 18, 5 and 14. Immunohistochemistry using this cocktail is useful for diagnosing proliferative intraductal breast lesions. However, cytology using the cocktail has not been reported.
Estudo comparativo de indicadores nutricionais em pacientes com neoplasias do trato digestório

RACIONAL: O câncer tem sido considerado atualmente como um dos principais problemas de saude publica em todo o mundo e os tumores mais frequentes sao os dos tratos gastrintestinal e o respiratorio. OBJETIVO: Comparar indicadores do estado nutricional em pacientes portadores de neoplasias do trato digestorio. METODO: Estudo comparativo de indicadores nutricionais (antropometricos, laboratoriais e dieteticos), entre 28 pacientes portadores de neoplasias do trato digestorio (esofagicas, gastricas e intestinais), em um hospital universitario. RESULTADOS: Nao foi encontrada diferenca significativa entre os tres grupos de neoplasia para os indicadores laboratoriais, de consumo alimentar e antropometricos, exceto para a circunferencia do braco (P=0,0471). A perda de peso ocorrida durante a internacao foi observada em 46,4% dos pacientes estudados e a dieta enteral foi a prescricao dietetica mais prevalente entre os pacientes, especialmente nos portadores de neoplasia de esofago. CONCLUSAO: Pacientes com diagnostico de neoplasia de trato digestorio apresentam comprometimento no estado nutricional e necessitam de acompanhamento nutricional no decorrer do tratamento destas enfermidades.
Principles of dental public health.

PART I: BACKGROUND 1. Public Health in Theory 2. Public Health in Practice 3. Milestones in Dental Public Health PART II: THE TOOLS OF DENTAL PUBLIC HEALTH 4. Biostatistics: Selection of Data 5. Biostatistics: Appraisal of Variability 6. Biostatistics: Correlation and Other Tests 7. Epidemiology: General Principles 8. Epidemiology: Dental Caries 9. Epidemiology: Periodontal and Other Diseases 10. The Social Sciences 11. Principles of Administration 12. Preventive Dentistry PART III: DENTAL HEALTH PROGRAMS 13. Dental Needs and Resources 14. Surveying 15. Dental Health Education 16. Water Fluoridation 17. Delivery of Dental Care 18. Payment for Dental Care 19. Evaluating the Quality of Dental Care 20. Community Dental Health Programs 21. Special Dental Health Programs 22. State Dental Health Programs 23. United States Federal Programs 24. Foreign and International Programs PART IV: THE FUTURE 25. Conquest or Equilibrium? References Index
Malignant Granular Cell Tumor of the Thyroid: A Case Report

1024x768 Normal 0 false false false 120 1024x768 Normal 0 false false false /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:. 0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Granular cell tumor is usually a benign tumor derived from nerve cells, occurring most often in the head and neck. Granular cell tumor originating from the thyroid gland is extremely rare and to date, none has been reported to exhibit malignant characteristics. We report a case of thyroid granular cell tumor with tracheal invasion. The patient was a 53-year-old man presenting a nodule in the left lobe of thyroid gland identified incidentally during a health check. The nodule was hard and elastic, and had a size of 3.5 cm in diameter. Fine needle aspiration was performed and cytology revealed clusters of cells with acidophilic cytoplasm. Considering the differential diagnosis from Hurthle cell neoplasm, diagnostic lobectomy was performed. During operation, tracheal invasion was identified, suggesting invasive follicular carcinoma. We therefore performed a total thyroidectomy with removal of the involved tracheal wall. The tumor was diagnosed postoperatively as thyroid granular cell tumor with tracheal invasion. Neither local recurrence nor distant metastasis was identified one year after the surgery. In this paper, we report and discuss this case with particular focus on the diagnostic difficulty for malignant granular cell tumor of thyroid. Â
Apraclonidine Hydrochloride as an Adjunct to Timolol Maleate Therapy

Twenty-four patients with primary open-angle glaucoma, uncontrolled on timolol 0.5% twice daily, were randomly assigned adjunctive therapy with either 0.0625%, 0.125%, or 0.25% apraclonidine or the vehicle of apraclonidine in a prospective, parallel, double-masked, 3-month study. All three concentrations of apraclonidine were associated with additional mean pressure reductions from baseline of 2–4 mm Hg at the majority of testing periods for the duration of the study. No clinically significant ocular or systemic adverse reactions were observed with the addition of apraclonidine to timolol therapy.
Spatial and temporal organization of the dominant frequencies in the fibrillating heart: body surface potential mapping in a rare case of sustained human ventricular fibrillation.

AIMS The aim of this study was to assess the spatial and temporal variability of dominant fibrillation frequencies in a rare case of sustained human ventricular fibrillation (VF). METHODS AND RESULTS Body surface potential mapping was performed in a patient with sustained VF and who was supported by a biventricular assist device. Dominant frequencies at 54 body sites were calculated from two recordings obtained 38 days apart. Variability of dominant frequencies between recordings and across body sites was quantified. Median dominant frequencies within recordings varied between 6.1 and 7.2 Hz in recording 1 and 5.6 and 6.6 Hz in recording 2, indicating a significant reduction in dominant frequencies between the recordings (P < 0.0001). Dominant frequencies differed across body sites by a mean (range) of 1.7 (0.4-2.8) Hz. CONCLUSION In this rare case of sustained VF, there was significant spatial and temporal variability of VF dominant frequencies. These findings should be considered in future ECG studies on VF where the spatial variability of dominant frequency might not otherwise have been considered.
Optimizing the treatment of atrial fibrillation: contributions by remote monitoring.

Despite more than a decade of intensified clinical research, our knowledge about atrial fibrillation (AF) is still far from satisfactory, and particularly the optimal treatment remains unclear. In fact, even the very basic question if attempts should be made to convert AF into sinus rhythm and to maintain it, or to simply limit the ventricular rate by drugs that slow atrioventricular conduction (and which strategy in whom? ) is not yet answered satisfactory. Results of the AFFIRM1 and AF-CHF2 trials were disappointing to a high degree showing no advantage of trying to maintain sinus rhythm or even a trend towards a higher mortality for ‘rhythm control’. This leads to the misinterpretation that AF seems to be harmless even in the context of heart failure. To avoid this, it should be pointed out that a post hoc analysis of the AFFIRM trial demonstrated that patients who were in sinus rhythm (no matter to which treatment group they were allocated) had a better … *Corresponding author. Tel: +49 69 6301 7387; fax: +49 69 6301 3813, E-mail address : C.W. Israel{at}em.uni-frankfurt.de
Neuropatia auditiva: estudo clínico em seis crianças

Objective: The goal of this research was to study 6 children with suspected Auditory Neuropathy(AN) of distinct etiologies. Methods: In each case, we determined the time of the first manifestations of the auditory loss and communication disorders, and submitted the patients to audiological subjective and objective tests. Results: The diagnostic of AN was made in all patients by the alteration of the neural function in contrast with the preservation of the cochlear function. A striking delay between the first manifestation of the disease and the final clinical diagnosis was observed in all cases. Conclusion: It was possible that the cause of the delay of the identification of the AN be the absence of audiological, eletrophysiological and clinical tests, responsible for the differential diagnosis. The clinical signs and symptoms of the children were heterogeneous as well as the possible etiologies of the AN in the studied cases.
Alcohol and substance use among transgender women in San Francisco: prevalence and association with human immunodeficiency virus infection.

INTRODUCTION AND AIMS Alcohol and substance use can have negative health consequences among both human immunodeficiency virus (HIV)-positive and -negative individuals, and are associated with behaviors that facilitate HIV transmission and acquisition. The relationship of substance use and HIV is well documented among key populations at risk for HIV. However, although transwomen (male-to-female transgender) are disproportionately impacted by HIV, this overlap remains understudied in this population. We sought to evaluate the association between HIV, alcohol and substance use among transwomen. DESIGN AND METHODS We conducted a secondary data analysis of Respondent Driven Sampling study which collected information on self-reported alcohol and substance use among 314 transwomen. We used multivariable logistic regression to assess relationship between HIV infection and classes and patterns of alcohol and substance use. RESULTS We found that 58% of transwomen used alcohol, and 43.3% used substances. The most common substances used were: marijuana (29%), methamphetamine (20.1%), crack cocaine (13.4%), and 'club drugs' (13.1%). Transwomen who reported any methamphetamine use [adjusted odds ratio (AOR) 3.02 (95% confidence interval (CI) = 1.51-6.02)], methamphetamine use before or during anal intercourse [AOR 3.27 (95% CI = 1.58-6.77)], and at least weekly methamphetamine use [AOR 3.89 (95% CI = 1.64-9.23)] had significantly greater odds of testing positive for HIV. DISCUSSION AND CONCLUSIONS Transfemales have high prevalence of alcohol and substance use; those tested positive for HIV used significantly more methamphetamine in general, and in conjunction with sex. Given the disproportionate prevalence of HIV and substance use in this population, interventions aimed at addressing both substance use and HIV risk among transwomen are urgently needed.
Complex T-wave morphology in body surface potential mapping in prediction of arrhythmic events in patients with acute myocardial infarction and cardiac dysfunction.

AIMS Heterogeneous ventricular repolarization is associated with sudden cardiac death after myocardial infarction (MI). This prospective study investigated repolarization disparity with parameters based on T-wave morphology in body surface potential mapping (BSPM) in the assessment of arrhythmia risk in patients with a recent MI and cardiac dysfunction. METHODS AND RESULTS Patients (n = 158) had 120-lead BSPM and 12-lead electrocardiogram (ECG) registered soon after acute MI. Principal component analysis (PCA) of the T-wave and T-wave vector loop descriptors were applied to compute parameters describing T-wave morphology and its variation. The study endpoints were arrhythmic events and all-cause mortality. During a mean follow-up of 50 months, 30 patients (19%) died and 16 (10%) had an arrhythmic event. Most of the parameters differed significantly between patients with and without arrhythmic events. In univariate analysis, T-wave vector loop length (TLL) and PCA parameter PCA(3) in BSPM and TLL in ECG were significant predictors of arrhythmic events. In multivariate analysis including several clinical variables, these parameters also showed an independent prediction, with parameters in BSPM performing somewhat better. None of the parameters predicted all-cause mortality. CONCLUSION Complex T-wave morphology in BSPM is a marker of arrhythmia propensity in patients with a recent MI and cardiac dysfunction.
Crack pipe sharing among street-involved youth in a Canadian setting.

INTRODUCTION AND AIMS Crack pipe sharing is a risky practice that has been associated with the transmission of hepatitis C and other harms. While previous research has exclusively focused on this phenomenon among adults, this study examines crack pipe sharing among street-involved youth. DESIGN AND METHODS From May 2006 to May 2012, data were collected from the At-Risk Youth Study, a cohort of street-involved youth aged 14-26 in Vancouver, Canada. Survey data from active crack smokers were analysed using generalised estimating equations logistic regression. RESULTS Over the study period, 567 youth reported smoking crack cocaine and contributed 1288 observations, among which 961 (75%) included a report of crack pipe sharing. In multivariate analysis, factors that were associated with crack pipe sharing included difficulty accessing crack pipes [adjusted odds ratio (AOR) = 1.58, 95% confidence interval (CI) 1.13-2.20]; homelessness (AOR = 1.87, 95% CI 1.43-2.44); regular employment (AOR = 1.53, 95% CI 1.15-2.04); daily non-injection crystal methamphetamine use (AOR = 2.04, 95% CI 1.11-3.75); daily crack smoking (AOR = 1.37, 95% CI 1.01-1.85); encounters with the police (AOR = 1.42, 95% CI 1.01-1.99); and reporting unprotected sex (AOR = 1.95, 95% CI 1.47-2.58). DISCUSSION AND CONCLUSIONS The prevalence of crack pipe sharing was high among our sample and independently associated with structural factors including difficulty accessing crack pipes and homelessness. Crack pipe sharing was also associated with high-intensity drug use and a number of other markers of risk and vulnerability. Collectively, these findings highlight opportunities for health services to better engage with this vulnerable group and reduce this risky behaviour.
A Comparison Study of Complication Rates – To PICC or to CVC?

Background: Cost-effective, safe and dependable central venous access is fundamental in the care of anpatients. This study sets out to compare the complication rates between electively insertedperipheral (PICCs) and central venous cathethers (CVCs) in operating theatres. Methods: A retrospective clinical audit was undertaken. Complications included in this study are: malposition events, thrombotic/thrombophlebitis, infectio n and dysfunctio n. Results: A total of 189 patients met the inclusion cr iteria. Malpositioning of the catheter tips and thrombotic/thrombophlebitic events more often occurred after PICCs insertion than CVCs. There was no statistical difference in the catheter associated infection and dysfunctio n rate for PICCs and CVCs. The highest number of complications occured in the first 7 indwelling days. Conclusion: This study highlights that the potential advantages of reduced expected cost- and labour- effectiveness of PICCs as traditionally perceived, may be inaccurate, and further awareness of complications associated with PICCs need to be considered.
Kongreßbericht: 34th European Symposium on Calcified Tissues, 5. bis 9. Mai 2007 in Kopenhagen

P . b . b . G Z 0 2 Z 0 3 1 1 0 8 M , V e r l a g s p o s t a m t : 3 0 0 2 P u r k e r s d o r f , E r s c h e i n u n g s o r t : 3 0 0 3 G a b l i t z Indexed in SCOPUS/EMBASE/Excerpta Medica www.kup. at/mineralstoffwechsel Österreichische Gesellschaft für Orthopädie und Orthopädische Chirurgie Österreichische Gesellschaft für Rheumatologie Offizielles Organ der Österreichischen Gesellschaft zur Erforschung des Knochens und Mineralstoffwechsels Member of the Kongreßbericht: 34th European