Miracle-dz/UniFAR-FTUs huggingface dataset:
Kobe University Repository : Kernel タイトル Tit le Cost ly apologies communicate conciliatory intent ion : an fMRI study on forgiveness in response to cost ly apologies 著者

Reconciliation is an integral part of our social lives. Nevertheless, if a victim perceives the risk of further exploitation by his/her transgressor as non-negligible, the victim may well have difficulty forgiving the transgressor. Therefore, a key ingredient of reconciliation is the transgressor’s sincere apology. Theoretical and empirical studies have shown that transgressors can make their apologies credible by incurring a substantial cost. Therefore, we hypothesized that costly apologies, compared to non-costly apologies (i.e., simply saying “sorry”), would effectively communicate a transgressor’s conciliatory intention. In a functional magnetic resonance imaging (fMRI) study, participants were asked to imagine a friend committing a mild interpersonal transgression (e.g., standing up the participant) and then apologizing in a costly fashion, apologizing in a non-costly fashion, or not apologizing at all. Compared to non-costly apologies and non-apologies, costly apologies (signals of conciliatory intention) more strongly activated the theory-of-mind network (i.e., bilateral temporoparietal junction, precuneus, medial prefrontal cortex). Moreover, we did not observe any significant differences in brain responses to non-costly apologies and non-apology controls. These results underscore the importance of costly signals in human communication and in human peace-making in particular.
Atopic Myelitis: An Emerging Cause of Myelitis in Korea

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TNFRSF 14 deficiency protects against ovariectomy-induced adipose tissue inflammation

To elucidate the role of tumor necrosis factor receptor superfamily member 14 (TNFRSF14) in metabolic disturbance due to loss of ovarian function, ovariectomy (OVX) was performed in TNFRSF 14-knockout mice. OVX increased fat mass and infiltration of highly inflammatory CD11c cells in the adipose tissue (AT), which was analyzed by flow cytometry, and resulted in disturbance of glucose metabolism, whereas TNFRSF14 deficiency attenuated these effects. TNFRSF14 deficiency decreased recruitment of CD11c-expressing cells in AT and reduced the polarization of bone marrow-derived macrophages to M1. Upon engagement of LIGHT, a TNFRSF14 ligand, TNFRSF14 enhanced the expression of CD11c via generation of reactive oxygen species, suggesting a role of TNFRSF14 as a redox modulator. TNFRSF14 participated in OVX-induced AT inflammation via upregulation of CD11c, resulting in metabolic perturbation. TNFRSF14 could be used as a therapeutic target for the treatment of postmenopausal syndrome by reducing AT inflammation.
University of Dundee Enabling designers to foresee which colors users cannot

Users frequently experience situations in which their ability to differentiate screen colors is affected by a diversity of sit­ uations, such as when bright sunlight causes glare, or when monitors are dimly lit. However, designers currently have no way of choosing colors that will be differentiable by users of various demographic backgrounds and abilities and in the wide range of situations where their designs may be viewed. Our goal is to provide designers with insight into the effect of real-world situational lighting conditions on people’s abil­ ity to differentiate colors in applications and imagery. We therefore developed an online color differentiation test that includes a survey of situational lighting conditions, verified our test in a lab study, and deployed it in an online environ­ ment where we collected data from around 30,000 partici­ pants. We then created ColorCheck, an image-processing tool that shows designers the proportion of the population they in­ clude (or exclude) by their color choices.
FACTORS ASSOCIATED WITH UPTAKE OF VOLUNTARY MEDICAL MALE CIRCUMCISION SERVICES AMONG ADULT MALES IN LUDEWA DISTRICT COUNCIL , NJOMBE REGION

Background: Male circumcision is the removal of some or the entire foreskin of the penis. In 2007, World Health Organization (WHO) adopted and recommended Voluntary Medical Male Circumcision (VMMC) to be implemented as an intervention for HIV prevention particularly in the country with high prevalence of HIV and low prevalence of Male circumcision. Since VMMC programme started in Ludewa DC in 2011 and early 2015, 83% of the procedures performed were for <20 years old clients. Little information are available on the factors associated with the uptake of VMMC services among adult males aged >20 years. Hence this study aimed to identify factors influencing uptake of voluntary medical male circumcision services among adult males aged >20 years in Ludewa DC. Materials and methods: An analytical cross-sectional study design was utilized. A multistage probability sampling method was used to randomly select adult males aged >20 years to be included in the study. Structured interviewer administered questionnaire was used in data collection. Data was entered, cleaned and analysed using Epi info version 3.5. 1. The p-value of <0.05 and OR at 95% was set as statistical significance level. Chisquare test was performed at bivariate level and those variables with p<0.2 were entered in Multiple logistic regression model to control for confounding and identify factors that are independently associated with uptake of VMMC services. Results: A total of 326 adult males aged >20 years were recruited in the study with the median age of 33 years (range 20 to 67 years). More than two third (66.6%) of the study respondents were circumcised. Having secondary and above education level (AOR=4.49; 95%CI: 2.58-7.81), availability of VMMC services (AOR=2.19; 95%CI: 1.21-3.96), pleasing of female partners (AOR=2.83; 95%CI: 1.63-4.93) and social support (AOR=1.78; 95%CI: 1.03-3.09) were independently associated with the uptake of VMMC services Conclusion and Recommendation: In this study, availability of VMMC services, education level, female partner support and social support were independently associated with uptake of VMMC services. Therefore, in order to increase coverage of circumcised adult males, involvement of women in the programme should be strengthened and also
Hotel Guest e-questionnaires : Implications for Feedback and Relationships

This paper examines the reliability and efficacy of hotel guest e-mail questionnaire compared to the paper questionnaire in the Asian Pacific context. Conducted inPerth,SingaporeandPenang, cities with mature hospitality and tourism industries and a representation of chain and independent deluxe hotels, this exploratory qualitative study examines hotelier views of e-mail guest communication derived from content analysis of guest questionnaires format and content and in-depth interviews with senior hoteliers. The findings indicated that e-questionnaires manifested as e-mails, as a direct replacement of the paper questionnaire, appear to be premature given divergent hotelier views and shortcomings in e-mail response administration. If properly executed, e-mail can play an increasingly important adjunct role to the paper guest questionnaire as a part of a multi-channel approach. The balance/relationship between ‘high tech’ and ‘high touch’ needs to be maintained: the latter can enhance the latter but should not undermine it.
Knowledge Workers ’ Expectations Towards a Digital Workplace Completed Research

The digitization around the workplace aims to increase a knowledge worker’s productivity and satisfaction level. In our study, we aim to validate the factors that drive an employee’s satisfaction within the current work environment and subsequently deduct the expectations towards the novel workplace. Analyzing the related literature, we’re able to derive the perceived key drivers for a new work environment and verify these within a large survey at a German headquartered global manufacturing company. With over 1,000 users questioned, we analyze our dataset with structural equation models and conclude, that the highest impact on the user’s satisfaction level is driven by the knowledge exchange amongst peers, followed by the perceived productivity and creativity. We could not find a significant impact of none of our demographic variables though. Our study concludes with recommendations for scholars and practitioners.
J ul 2 01 9 Constructing sparse Davenport-Schinzel sequences

For any sequence u, the extremal function Ex(u, j, n) is the maximum possible length of a jsparse sequence with n distinct letters that avoids u. We prove that if u is an (r, s)-formation, then Ex(u, j, n) = Θ(snr) for all j ≥ r and s ≥ n. As a corollary, we answer a question about sparse Davenport-Schinzel sequences from Wellman and Pettie [Lower Bounds on Davenport-Schinzel Sequences via Rectangular Zarankiewicz Matrices, Disc. Math. 341 (2018), 1987–1993] and extend the result of Roselle and Stanton that Ex(u, 2, n) = Θ(sn) for any alternation u of length s ≥ n [Some properties of Davenport-Schinzel sequences, Acta Arithmetica 17 (1971), 355–362]. Wellman and Pettie also asked how large must s(n) be for there to exist n-block DS(n, s(n)) sequences of length Ω(n). We answer this question by showing that the maximum possible length of an n-block DS(n, s(n)) sequence is Ω(n) if and only if s(n) = Ω(n). We also show related results for extremal functions of forbidden 0-1 matrices with any constant number of rows and extremal functions of forbidden sequences with any constant number of distinct letters.
Title : European Psychiatric Association ( EPA ) guidance on forensic psychiatry : Evidence based assessment and treatment of mentally disordered offenders

Forensic psychiatry in Europe is a specialty primarily concerned with individuals who have either offended or present a risk of doing so, and who also suffer from a psychiatric condition. These mentally disordered offenders (MDOs) are often cared for in secure psychiatric environments or prisons. In this guidance paper we first present on overview of the field of forensic psychiatry from a European perspective. We then present a review of the literature summarising the evidence on the assessment and treatment of MDOs under the following headings: The role of the forensic psychiatrist as an expert witness, risk assessment, treatment settings for MDOs, and effectiveness of psychological and pharmacological interventions. We undertook a rapid review of the literature with search terms related to: forensic psychiatry, review articles, randomised controlled trials and best practice. We searched the Medline, Embase, PsycINFO, and Cochrane library databases from 2000 onwards for adult groups only. We scrutinised publications for additional relevant literature, and searched the websites of relevant professional organisations for policies, statements or guidance of interest. We present the findings of the scientific literature as well as recommendations for best practice drawing additionally from the guidance documents identified. We found that the evidence base for forensic-psychiatric practice is weak though there is some evidence to suggest that psychiatric care produces better outcomes than criminal justice detention only. Practitioners need to follow general psychiatric guidance as well as that for offenders, adapted for the complex needs of this patient group, paying particular attention to long-term detention and ethical issues.
Interactive comment on “ The Effects of Sea Spray and Atmosphere-Wave Coupling on Air-Sea Exchange during Tropical Cyclone ”

Ans: In our study, we used COARE2.6 as Andreas’s model uses COARE2.6 also. Also, this parametrization has been used in numerous publications by Andreas and his co-authors. We do understand reviewer’s concern, however, we would like to mention that this is in-line with the standard practice. Besides using HEXOS data (DeCosmo, 1991), we have also conducted further tests (not presented in the paper) using FASTEX data (Persson et al., 2005) and found little effect on the value of coefficients.
MIGRATED LEGACY DATA ISSUES - RECOVERY, CONCURRENCY & SECURITY

This paper presents the management and rectification of the data pertaining to an Enterprise Information System after being migrated from Legacy Information sources. The experience from using this research shows that the basic parameters like Recovery, Concurrency and Security could be attained in a better way after migration to new Systems from Legacy Systems. A major anxiety at the first glance is about data retaining its integrity at a large extent as was being attained in Legacy Systems also. At present, the Data Warehouse used by the Enterprise under research is the centralized database that it uses for many tasks pertaining to Finance, Management, Marketing, Human Resource Development Personnel Management, etc. Evidently, there is not much data protection control available. Hence, if something adversely happened, the Central Data Warehouse will be directly affected and may lead to a system crash especially by those users who are not aware of the mistake when using the new migrated system. Unexpected and unexplored problems might also occur and may need a tremendous amount of work to rectify such data inconsistencies after migration.
Public funds and internal innovation goals as drivers of open innovation practices: A European regional comparison

Open innovation (OI) has demonstrated to be crucial in increasing firms’ innovation and economic performance, but there is still limited understanding about the drivers of inbound OI. Our main goal is to shed light in this direction by simultaneously analysing the firms’ internal and external drivers of formal and informal OI practices. In order enrich the analysis and to obtain more robust results we test our hypotheses on samples from two European regions, Navarre (Spain), classified an innovator follower, and Noord Brabant (Netherlands), an innovator leader. Results indicate that, for the internal drivers, product-related motives to innovate and in-house R&D intensity are strong drivers for both formal and informal OI engagement, while processand environmental-related motives are context dependent. As for the external drivers we observed that public policy influences the formal and informal OI adoption but effects vary across regions depending on origin of funds
Wound healing mechanism of antimicrobial peptide cathelicidin-DM

Background and Purpose: Chronic wound infections and the development of antibiotic resistance are serious clinical problems that affect millions of people worldwide. Cathelicidin-DM, an antimicrobial peptide from Duttaphrynus melanostictus, has powerful antimicrobial activity and wound healing efficacy. So, it could be a potential candidate to address this problem. In this paper, we investigate the wound healing mechanism of cathelicidin-DM to establish a basis for preclinical studies of the drug. Experimental Approach: The effects of cathelicidin-DM on cell proliferation and migration, cytokines, and mitogen-activated protein kinase (MAPK) signaling pathways were examined. Then mice whole skin wound model was constructed to evaluate the wound healing activity of cathelicidin-DM, and further histological changes in the wounds were assessed by hematoxylin-eosin staining (H&E) and immunohistochemical assays. Key Results: Cathelicidin-DM promotes the proliferation of HaCaT, HSF, and HUVEC cells in a concentration-dependent manner and the migration of HSF, HUVEC, and RAW.264. 7 cells. Moreover,cathelicidin-DM can involve in wound healing through activation of the MAPK signaling pathway by upregulating phosphorylation of ERK, JNK, and P38. However, cathelicidin-DM didn’t affect the secretion of IL-6 and TNF-α. At the animal level, cathelicidin-DM accelerated skin wound healing and early debridement in mice as well as promoted re-epithelialization and granulation tissue formation, α-SMA expression, and collagen I deposition in mice. Conclusion and Implications: Our data suggest that cathelicidin-DM can be engaged in the healing of infected and non-infected wounds through multiple pathways, providing a new strategy for the treatment of infected chronic wounds.
How Much Does Corporate Effect matter ? Definition and Estimation of Business-Variant Corporate Effect

This paper argues that previous variance decomposition studies analyzing the extent to which industry, corporate, or business effects explain business performance fail to account for uneven impact of corporate decision on subsidiaries, then systematically underestimating corporate effects. To better account for the impact of corporate decisions, we assume that depending on specific characteristics of a business unit compared to its sister businesses, the likelihood to receive above (or below) average resources will differ, thus affecting its performance. We find that business-variant corporate effects significantly matter. Furthermore, the explanatory power of our model in explaining business performance increases by 27.8% in absolute terms and around 55% in relative terms when introducing business-variant corporate effects.
EasyChair Preprint No 1031 A Big Data / Analytics Platform for Industry 4 . 0 Implementation in SMEs

Industrial companies operate in an increasingly competitive international environment. SMEs are among the most weak companies in this context and need to continuously innovate to increase their competitiveness, productivity and the quality of their products. Digital transformation, one of the foundations of Industry 4.0, is therefore fundamental to meeting these innovation challenges. The objective of the study is to present the methodology, development and implementation of a new cloud computing platform to collect, store and process data from industrial SME shopfloors.companies' manufacturing shopfloors employ more and more connected and intelligent devices producing thousands of data that once computed achieve a high added value. The study presents the architecture for collecting this data and storing it in a Big Data solution, and then processing it with advanced artificial intelligence algorithms and/or optimization techniques. This platform has been developed with the aim of minimizing complexity and costs to facilitate the adoption of the platform by SMEs. The implementation and evaluation of the platform was carried out in three companies from three different sectors of Brazilian industry.
Physiological effects of γ-aminobutyric acid application on cold tolerance in Medicago ruthenica

Low temperatures in the seedling stage during early spring limit Medicago ruthenica germination and seedling growth. Elucidating the physiological mechanism of γ-aminobutyric acid (GABA)-regulated cold tolerance in M. ruthenica could provide a reference for alleviating the harmful effects of low temperatures on legumes in alpine meadows. The regulatory effects of GABA on M. ruthenica physiological parameters were explored by simulating the ground temperatures in the alpine meadow area of Tianzhu, China, in early May (2 h at 7°C; 6 h at 15°C; 4 h at 12°C; 2 h at 7°C; 10 h at 3°C). Our results showed that 15 mmol/l GABA was the optimal spray concentration to promote growth in the aboveground and belowground parts and increase the fresh and dry weights of seedlings. At this concentration, GABA enhanced the activities of catalase, peroxidase, superoxide dismutase, and ascorbate peroxidase; increased the osmotic balance; and inhibited the production of harmful substances in the cells under low-temperature conditions. GABA also regulated the tissue structure of leaves, increased the cell tense ratio, maintained photochemical activity, increased the amount of light energy to the photochemical reaction center, and improved the photosynthetic rate. Furthermore, exogenous GABA application increased the endogenous GABA content by promoting GABA synthesis in the early stages of low-temperature stress but mainly participated in low-temperature stress mitigation via GABA degradation in the late stages. Our results show that GABA can improve the cold tolerance of M. ruthenica by promoting endogenous GABA metabolism, protecting the membrane system, and improving the leaf structure.
Academic Performance in Double-Shift Schooling January 12 , 2015

Many developing countries with constrained resources have adopted the double-shift schooling system as a way to serve more students. However, there is some concern that some students may be hurt by these policies. With a unique dataset from Mexico’s National Institute for Educational Assessment and Evaluation (INEE), I apply Heckman′s selection model to measure the effects of individual, teacher, and school characteristics on student test scores and estimate the difference in academic performance of students in morning and afternoon school sessions. While I find a statistically significant effect of being in the morning shift, the Oaxaca decomposition shows that this effect can be explained by the observed difference in characteristics of students from two shifts. The results show that self-selection of students to schooling sessions explains the apparent academic inequality between students from different sessions. The author is grateful to Ronald Oaxaca, Price Fishback, and Tiemen Woutersen for continuos guidance and support. Thanks also to Jessamyn Schaller, Ashley Langer, Ming-Sen Wang, Taylor Jaworski, and Rodrigo Duran Parral for valuable comments and suggestions. Research results and conclusions expressed are those of the author.
Lack of panmixia of Bothnian Bay vendace - Implications for fisheries management

Overexploitation of fisheries is recognized as a major environmental and socioeconomic problem that threats biodiversity and ecosystem functioning. Inappropriate management policies of fish stocks have been applied as a consequence of inadequate characterization of subtle genetic structure in many fish species. In this study, we aim to assess the extent of genetic differentiation and structure of vendace (Coregonus albula) collected from eight locations in the Bothnian Bay, the northernmost part of the Baltic Sea. Specifically, we test if this species forms a single panmictic population or is divided into several genetically distinct units. We used restriction site-associated DNA sequencing (RAD-seq) to identify 21,792 SNPs based on 266 individuals. We identified a clear pattern of genetic differentiation between River Kalix and the other sampling locations, and a weak structuring between samples from Swedish and Finnish coast. Outlier analysis detected 41 SNPs putatively under divergent selection, mainly reflecting the divergence between River Kalix and the other samples. The outlier SNPs were located within or near 25 genes, including voltage-dependent calcium channel subunit alpha-2 (CACNA2D2), cadherin 26 (CDH26) and carbonic anhydrase 4-like (CA4) that have earlier been associated with salt-tolerance and salinity stress. Our study provides the first genome-wide perspective on genetic structuring of Baltic Sea vendace and rejects the hypothesis of panmixia in the Bothnian Bay. As such, our work demonstrates the power of RAD-sequencing to detect low but significant genetic structuring relevant for fisheries management.