Miracle-dz/UniFAR-FTUs huggingface dataset:
An Enhancement Role and Attribute Based Access Control Mechanism in Big Data

To be able to leverage big data to achieve enhanced strategic insight and make informed decision, an efficient access control mechanism is needed for ensuring end to end security of such information asset. Attribute Based Access Control (ABAC), Role Based Access Control (RBAC) and Event Based Access Control (EBAC) are widely used access control mechanisms. The ABAC system is much more complex in terms of policy reviews, hence analyzing the policy and reviewing or changing user permission are quite complex task. RBAC system is labor intensive and time consuming to build a model instance and it lacks flexibility to efficiently adapt to changing user’s, objects and security policies. EBAC model considered only the events to allocate access controls. Yet these mechanisms have limitations and offer feature complimentary to each other. So in this paper, Event-Role-Attribute based fine grained Access Control mechanism is proposed, it provide a flexible boundary which effectively adapt to changing user’s, objects and security policies based on the event. The flexible boundary is achieved by using temporal and environment state of an event. It improves the big data security and overcomes the disadvantages of the ABAC and RBAC mechanisms. The experiments are conducted to prove the effectiveness of the proposed Event-Role-Attribute based Access Control mechanism over ABAC and RBAC in terms of computational overhead.
ANovel BLDC-Like DTC Control Technique for InductionMotors

DC brushless motors are widely adopted for their simplicity of control, even in sensorless configuration, and their high torque density. On the other hand, induction motors are very economical due to the absence of permanent magnets; for the same reason they can easily be driven in the flux-weakening region to attain a wide speed range. Nevertheless, high dynamic induction motors drives, based on field-oriented (FOC) or predictive control, require large amounts of computing power and are rather sensitive to motor parameter variations. This paper presents a simple DTC induction motor control algorithm based on a well-known BLDC control technique, which allows to realize a high dynamic induction motor speed control with wide speed range. The firmware implementation is very compact and occupies a low amount of program memory, comparable to volt-per-Hertz(V/f-) based control algorithms. The novel control algorithm presents also good performance and low current ripple and can be implemented on a low-cost motion control DSP without resorting to high-frequency PWM.
Response to interactive comment on “ Atmospheric oxidation of isoprene and 1 , 3-butadiene : influence of aerosol acidity and relative humidity on secondary organic aerosol ” by

11 The effects of acidic seed aerosols on the formation of secondary organic aerosol (SOA) 12 have been examined in a number of previous studies, several of which have observed strong 13 linear correlations between the aerosol acidity (measured as nmol H per m air sample volume) 14 and the percent change of secondary organic carbon (SOC). The measurements have used several 15 precursor compounds representative of different classes of biogenic hydrocarbons including 16 isoprene, monoterpenes, and sesquiterpenes. To date, isoprene has displayed the most 17 pronounced increase in SOC, although few measurements have been conducted with 18 anthropogenic hydrocarbons. In the present study, we examine several aspects of the effect of 19 aerosol acidity on the secondary organic carbon formation from the photooxidation of 1,320 butadiene, as well as extending the previous analysis of isoprene. 21 The photooxidation products measured in the absence and presence of acidic sulfate 22 aerosols were generated either through photochemical oxidation of SO2 or by nebulizing 23 mixtures of ammonium sulfate and sulfuric acid into a 14.5 m smog chamber system. The 24 results showed that, like isoprene and β-caryophyllene, 1,3-butadiene SOC yields linearly 25 correlate with increasing acidic sulfate aerosol. The observed acid sensitivity of 0.11 %SOC 26 increase per nmol m increase in H was approximately a factor of three less than that measured 27 for isoprene. The results also showed that the aerosol yield decreased with increasing humidity 28
Artyku∏ na zaproszenie redakcji Swoista indukcja apoptozy w komórkach nowotworowych

Przedmiotem pracy jest swoista indukcja apoptozy w komórkach nowotworowych. W pracy omówiono najbardziej podstawowe i charakterystyczne w∏aÊciwoÊci apoptozy (programowej Êmierci komórek). Apoptoza mo ̋e byç indukowana w komórkach za poÊrednictwem zewn ́trznych sygna∏ów natury bia∏kowej, pochodzàcych od innych komórek. Mo ̋e byç tak ̋e wywo∏ana w komórkach ró ̋nymi czynnikami stresu (np. uszkodzenia DNA, niedotlenowanie komórek, aktywacja onkogenów). Jednà z podstawowych funkcji apoptozy jest eliminacja komórek, w których np. uszkodzenia DNA, wadliwa proliferacja, niew∏aÊciwa adhezja do macierzy pozakomórkowej nie mogà byç usuni ́te lub naprawione. W regulacji procesu apoptozy biorà udzia∏ zarówno bia∏ka proapoptotyczne, jak i bia∏ka antyapoptotyczne. Od ich wzajemnych relacji zale ̋y, czy w komórkach zostanie wyindukowana apoptoza. W komórkach nowotworowych obserwuje si ́ wzrost opornoÊci komórek nowotworowych na wi ́kszoÊç sygna∏ów indukujàcych apoptoz ́. W powstawaniu fenotypu opornego na apoptoz ́ wa ̋nà rol ́ odgrywajà mutacje genów kodujàcych bialka proapoptotyczne, jak i genów kodujàcych inhibitory apoptozy. Mutacje genów proapoptotycznych prowadzà do zmniejszenia aktywnoÊci bia∏ek proapoptotycznych, natomiast mutacje genów antyapoptotycznych do wzrostu aktywnoÊci inhibitorów apoptozy. Wprowadzenie do komórek nowotworowych genów kodujàcych proapoptotyczne bia∏ka indukuje w nich apoptoz ́. Niektóre geny kodujàce bia∏ka proapoptotyczne pochodzenia wirusowego (np. gen E4orf4 adenowirusów czy gen kodujàcy apoptyn ́ wirusa CAV, ang. chicken anemia virus) indukujà w wysoce swoisty sposób apoptoz ́ w komórkach nowotworowych, a nie w komórkach prawid∏owych. Bia∏ka takie mogà staç si ́ podstawà nowej generacji przeciwnowotworowych leków.
Studies on the performance of promising varieties of oat ( Avena sativa L . ) under different cutting regimes in mid hill conditions of Himachal Pradesh

A field experiment was conducted to study the performance of promising varieties of oat under different cutting regimes. Amongst the oat varieties tested, Palampur-1 recorded significantly higher tiller number per metre row length and better leaf stem ratio compared to other varieties. Tiller number also increased with each delay in harvesting stage and highest tiller number was recorded at 50 per cent flowering stage, however, significantly highest leaf stem ratio was in fodder harvested at 30 cm plant height. Significantly higher total green (329 q ha) and dry (185 q ha) fodder yields were obtained with Palampur-1 harvested at 50 per cent flowering stage compared to other varieties with different cutting regimes. Comparatively better net returns and net returns per rupee invested were obtained with variety Palampur1 and cutting at 50 per cent flowering stage. However, cutting at 45 cm height fetched better green fodder yield than cutting at 60 cm height which gave regular fodder supply with good green fodder yield thus suggesting it good for small and marginal farmers.
ModerateWeight Loss Decreases Oxidative Stress and Increases Antioxidant Status in Patients with Metabolic Syndrome

Background. Oxidative stress is enhanced in metabolic syndrome (MetS) and believed to contribute to accelerated atherosclerosis. Weight loss is associated with lowered oxidative stress. Methods. We performed a cross-sectional study in 92 consecutive patients with metabolic syndrome and 80 without. A dietary intervention with moderately low-calorie diet (600 calories/day negative energy balance) was carried out in 53 of metabolic syndrome patients. Oxidative stress, assessed by sNOX2-dp and urinary 8iso-PGF2α, and antioxidant status, assessed by serum levels of vitamin E and adiponectin, were measured before and after 6 months. Results. Serum vitamin E/cholesterol ratio was significantly lower in metabolic syndrome compared to controls (P < 0.001) and decreased by increasing the number of metabolic syndrome components (P < 0.001). After six months, 23 and 30 patients showed >5% (group A) or <5% (group B) weight loss, respectively. Urinary 8-iso-PGF2α (−39.0%), serum sNOX2-dp (−22.2%), adiponectin (+125%), and vitamin E/cholesterol ratio (+129.8%) significantly changed only in A group. Changes in body weight and in serum adiponectin were independent predictors of vitamin E/cholesterol ratio variation. Conclusion. Our findings show that in metabolic syndrome moderate weight loss is associated with multiple health benefits including not only oxidative stress reduction but also enhancement of antioxidant status.
Barycypraea teulerei ( Cazenavette , 1845 ) ( Gastropoda Cypraeidae ) : a successful species or an evolutionary dead-end ?

Received 23.02. 2016; accepted 22.03. 2016; printed 30.03. 2016 Proceedings of the Ninth Malacological Pontine Meeting, October 3rd-4th, 2015 San Felice Circeo, Italy Barycypraea teulerei (Cazenavette, 1845) (Gastropoda Cypraeidae) is an unusual cowrie species, showing remarkable adaptations to an uncommon environment. It lives intertidally on flat sand/mud salt marshes, in a limited range, in Oman. On Masirah Island, humans probably drove it to extinction because of shell collecting. A new population, with a limited range, has recently been discovered, and this article describes observations I made on site in 2014. Evolution shaped this species into a rather specialized and successful life, but has also put it at risk. Barycypraea teulerei is well adapted to survive in its habitat, but at the same time is easily visible and accessible to humans, and this puts it at high risk of extinction. Evolution is indeed a blind watchmaker that ‘has no vision, no foresight, no sight at all’. And B. teulerei was just plain unlucky to encounter our species on its journey on our planet.
45 Protective and Regenerative Autoimmunity in CNS Injury

Neurodegenerative diseases are generally considered to be non-inflammatory, unlike autoimmune diseases such as multiple sclerosis, which are neurodegenerative diseases that are inflammatory in nature (Trapp et al., 1999a, b; Hohlfeld and Wiendl, 2001; Groom et al., 2003). Nevertheless, most neurodegenerative diseases are accompanied by a local inflammatory response, widely assumed to be unfavorable for CNS recovery (Kurosinski and Gotz, 2002; Jellinger, 2003; Popovich and Jones, 2003). Moreover, the progressive degeneration seen in such diseases is often mediated by compounds and processes that are secondary to the primary risk, e.g., misfolding and aggregation of self-proteins (Shastry, 2003). These primary and secondary risk factors represent a continuous threat to any viable neurons embedded in a chronically diseased tissue; they induce abnormalities in cells in their vicinity, thereby contributing to the chaos rather than helping to resolve it. Another feature common to most of the chronic neurodegenerative conditions is age dependence. The incidence of Alzheimer’s and Parkinson’s disease, glaucoma, and many others increases significantly with age (Ossowska, 1993; Mattson, 2003). As will be discussed below the age factor might not be related only to the aging of the brain but also to age-related changes in the immune system. Often the removal of the primary risk factor does not stop disease progression, and the neurodegeneration continues (Weinreb and Levin, 1999; Schwartz and Cohen, 2000). In Parkinson’s disease, for example, despite dopamine (L-dopa) treatment as a replacement therapy the dopaminergic neurons continue to die (Hirsch, 1999; Montastruc et al., 1999). In glaucoma, reduction of intraocular pressure often does not stop disease progression (Schwartz et al., 1996). This progressive degeneration, which continues despite removal of the presumed primary risk factor(s), has been linked to what has been recognized as secondary degeneration. Emerging risk factors have been attributed to this phenomenon, including inflammationassociated factors. This has been studied intensively in recent years with a major focus on the balance between the benefit and the risk of uncontrolled immune activity, which exceeds the ability of the CNS to tolerate it.
THE AUSTRALIAN NATIONAL UNIVERSITY WORKING PAPERS IN ECONOMICS AND ECONOMETRICS A Model of Seller Holdout *

We model a buyer who wishes to combine objects owned by two separate sellers in order to realize higher value. Sellers are able to avoid entering into negotiations with the buyer, so that the order in which they negotiate is endogenous. Holdout occurs if at least one of the sellers is not present in the first round of negotiations. We demonstrate that complementarity of the buyer’s technology is a necessary condition for equilibrium holdout. Moreover, a rise in complementarity leads to an increased likelihood of holdout, and an increased efficiency loss. Applications include patents, the land assembly problem, and mergers. * We thank Paulo Monteiro and John Quiggin for many helpful comments. Menezes gratefully acknowledges the financial support of ARC (Grant no. A000000055).
Bringing HIV Self-Testing to Scale in the United States: a Review of Challenges, Potential Solutions, and Future Opportunities

HIV self-testing (HIVST) provides an at-home option to counter the barriers that patients face with testing performed in health care settings. HIVST has gradually increased in popularity in a time when social media and technology-based solutions are preferred. In this paper, we consider the aspects of self-testing that merit its integration into HIV testing and prevention systems in the United States. ABSTRACT HIV self-testing (HIVST) provides an at-home option to counter the barriers that patients face with testing performed in health care settings. HIVST has gradually increased in popularity in a time when social media and technology-based solutions are preferred. In this paper, we consider the aspects of self-testing that merit its integration into HIV testing and prevention systems in the United States. Several elements favor self-testing for large-scale implementation, including ease of use, convenience, potential for integration with mobile health (mHealth), and availability for various modes of distribution. HIVST has a demonstrated ability to reach at-risk individuals who otherwise rarely test. The paradigm of self-testing, however, introduces new challenges, including lesser test performance relative to that in health care settings, nonstandard counseling following receipt of test results, and difficulty in providing linkage to care. After discussing the performance of oral fluid versus blood-based HIVST, we review data regarding acceptability of HIVST, offer insights into counseling and linkage to care for HIVST, and provide examples of novel applications of and future research directions for HIVST.
ELDERLY ADULTS WITH ISOLATED HIP FRACTURES - ORTHOGERIATRIC CARE VERSUS STANDARD CARE: A PRACTICE MANAGEMENT GUIDELINE FROM THE EASTERN ASSOCIATION FOR THE SURGERY OF TRAUMA.

BACKGROUND Elderly patients commonly suffer isolated hip fractures, causing significant morbidity and mortality. The use of orthogeriatrics (OG) management services, in which geriatric specialists primarily manage or co-manage patients after admission, may improve outcomes. We sought to provide recommendations regarding the role of OG services. METHODS Using GRADE methodology with meta-analyses, the Practice Management Guidelines Committee of the Eastern Association for the Surgery of Trauma conducted a systematic review of the literature from January 1, 1900 to August 31, 2017. A single PICO question was generated with multiple outcomes: Should geriatric trauma patients aged 65+ with isolated hip fracture receive routine OG management, compared to no routine OG management, to decrease mortality, improve discharge disposition, improve functional outcomes, decrease in-hospital medical complications, and decrease hospital length of stay. RESULTS Forty-five manuscripts were evaluated. Six randomized controlled trials and seven retrospective case-control studies (RCCS) met criteria for quantitative analysis. For critical outcomes, RCCS demonstrated a 30-day mortality benefit with OG (OR 0.78[0.67, 0.90]), but this was not demonstrated prospectively or at one year. Functional outcomes were superior with OG, specifically improved score on the Short Physical Performance Battery at four months (MD 0.78 [0.28, 1.29]), and improved score on the Mini Mental Status Exam with OG at 12 months (MD 1.57 [0.40, 2.73]). Execution of activities of daily living was improved with OG as measured by two separate tests at four and twelve months. There was no difference in discharge disposition. Among important outcomes, the OG group had fewer hospital-acquired pressure ulcers (OR 0.30 [0.15, 0.60]). There was no difference in other complications or length of stay. Overall quality of evidence was low. CONCLUSIONS In geriatric patients with isolated hip fracture, we conditionally recommend an OG care model to improve patient outcomes. LEVEL OF EVIDENCE Level III evidenceSystematic Review/Meta-Analysis.
Effect of ethanolic extract of Excoecaria agallocha leaves on the cytotoxic activity and cell cycle arrest of human breast cancer cell lines – MCF-7

Background: At present, Mangrove plants have gained importance in drug discovery due to the presence of many phytomolecules of medicinal importance. Excoecaria agallocha is widely distributed medicinal mangrove which has been traditionally used to treat sores, ulcers, and leprosy. Objective: The aim of the present study is to analyze the cytotoxic potential of Exoecaria agallocha leaves in terms of its antiproliferative activity, apoptosis induction, and cell cycle arrest in the breast cancer MCF-7 cell lines. Materials and Methods: The ant proliferative nature of the EEEA extract was determined by direct microscopic observation as well as 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-tetrazolium bromide (MTT) assay by employing the different concentrations of the plant extract, and the IC50 values were calculated. Apoptosis-inducing potential was determined by double staining with acridine orange/ethidium bromide staining method and further confirmed by annexin V staining. Flow cytometry was performed with IC50 concentration of EEEA drug treated MCF-7 cells to determine arresting stage in the cell cycle progression. Results: There was a significant cytotoxic activity exhibited by the ethanolic extract of E. agallocha leaves (EEEA) in the direct microscopic as well as MTT assay with IC50 value of 56.5 μg/ml. Well prominent fluorescent microscopic images of morphological changes in the double staining method indicate the apoptotic potential of the extract which was further confirmed by annexin V staining. Suppression of cell cycle progression at subG1 and G1/G2 phases were also evidenced in the flow cytometry analysis. Conclusion: From the above results, it may be concluded that the ethanolic leaf extract of E. agallocha (EEEA)-induced apoptosis mediated cytotoxic and antiproliferative activity in the breast cancer MCF-7 cell lines which can be developed into a new drug for treating breast cancer.
Isogeny-based hashing despite known endomorphisms

The Charles–Goren–Lauter hash function on isogeny graphs of supersingular elliptic curves was shown to be insecure under collision attacks when the endomorphism ring of the starting curve is known. Since there is no known way to generate a supersingular elliptic curve with verifiably unknown endomorphisms, the hash function can currently only be used after a trusted-setup phase. This note presents a simple modification to the construction of the hash function which, under a few heuristics, prevents said collision attack and permits the use of arbitrary starting curves, albeit with a performance impact of a factor of two.
Interferon-signature in idiopathic inflammatory myopathies.

PURPOSE OF REVIEW The present review describes the interferon (IFN)-signature currently emerging as a tool for the diagnosis of idiopathic inflammatory myopathies (IIMs), and aims at presenting the interests and limitations of this recent tool for the clinics and the research. RECENT FINDINGS Recent in-vivo and in-vitro transcriptomic studies have evidenced the involvement of IFNs in the pathogenesis of IIMs. A correlation between the IFN-signature and the clinical severity of IIMs has been established. Moreover, studies pointed out differences in the IFN-signature regarding the IIM subgroup (dermatomyositis, polymyositis, inclusion body myositis, anti-synthetase syndrome, immuno-mediated necrotizing myopathies), raising the hypothesis of several pathogenic processes in IIMs. SUMMARY IIM pathogenesis remains partially understood. IFN-signature represents one of the main recent advances in the field. IFN-signature was identified thanks to transcriptomic analyses of tissues or cells from IIM patients (muscle, skin, blood cells, muscle cells) and should allow to establish new diagnosis and better monitoring of IIM patients. It also provides a tool for investigation of IIM pathogenesis. Nevertheless, IFN-signature still requires accurate definition in order to standardize its use, notably in the clinical practice.
Evaluation of the quality of local butters: A new approach based on Raman spectroscopy and supported by the classical pycnometer method

In this study, the quality of the local Romanian butters was investigated using the classical pycnometer and optic microscopy methods, combined with Raman spectroscopy. We used a pool of 10 samples with different characteristics, and analyzed them by the three aforementioned methods. Pycnometric measurements showed a direct correlation between the fat content and the density values of the samples. Raman spectroscopy validated the results from the pycnometric measurements and the optical microscopy and indicated several other properties, such as protein content, hydration, saturation level of the polycarbonate chains, as well as the total cis isomer content and the type of arrangement preferred by the aliphatic chains (polymorphic transition). The methods employed in the present study have a strong potential to become analytical tools for the food industry and food safety agencies in order to assess the quality of butters and margarines, in a fast and cost-effective manner.