Miracle-dz/UniFAR-FTUs huggingface dataset:
LisMath seminar 2014/2015, 2nd semester

We will present a family of time reversible stochastic processes known (among other names) as Bernstein processes [1,2]. These processes are much closer, in their properties, to the solutions of deterministic (Lagrangian or Hamiltonian) dynamical equations, they are in fact absolutely continuous with respect to the Wiener process, i.e. they are processes with a drift term. The relevant Feynman-Kac formula for this class of processes will be proved. Some particular cases of the formula will be given as examples: the well-known Feynman-Kac formula and Doob’s relation between Wiener and Ornstein-Uhlenbeck processes [3,4]. The consequences of this probabilistic perturbation theory and the underlying time reversible processes should go beyond stochastic analysis. We will give a hint of two applications, one motivated by mathematical quantum physics and the other by a stochastic version of geometric mechanics. The first concerns a rigorous probabilistic interpretation of Feynman informal perturbation theory in his Path Integral approach [7], which needs the development of a rigorous integration by parts formula, also inspired by Feynman, done in terms of special reversible probability measures on path space [6]. Furthermore, to investigate the consequences of this probabilistic perturbation theory in the more general context of stochastic analysis.
Analytical Solutions of Computer Virus Propagation Model with Anti-virus Software and Time Dependent Connecting Network in Caputo Fractional Derivative Sense

Computer viruses and related malware are major problems for personal and corporate computers and for computer networks. A common approach to prevent the destructive effects of viruses on computers is to install anti-virus programs on individual computers. An alternative approach to prevent the propagation of viruses in computer networks is to use mathematical models similar to those developed for understanding and preventing the spread of epidemics in human, animal or plant populations. In this paper, we focus on the fully susceptible, partially susceptible, infectious, protected (FSSIP) model including Caputo fractional derivative to study the effect of anti-virus software on infection in computer networks. We apply the shifted Chebyshev collocation method to obtain analytical solutions (series solutions) of the FSSIP model with the virus input into each group which is time-dependent function due to the appearance of new viruses and updating of the installed anti-virus software. This method is simple, efficiency, and accurate when comparing the numerical results to Runge-Kutta-Fehlberg method (RKF45) and Cash-Karp method (CK45).
A FULL-NEWTON ALGORITHM FOR PARAMETER ESTIMATION IN UNSATURATED SOILS

aCONICET, Departamento de Geofı́sica Aplicada, Facultad de Cs. Astronómicas y Geofı́sicas, UNLP, Paseo del Bosque s/n (B1900FWA), La Plata, Argentina, luisg@fcaglp.unlp.edu.ar, http://www.fcaglp.unlp.edu.ar bCONICET, Instituto de Cálculo, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, Argentina, efernan@ic.fcen. uba.ar cDepartment of Mathematics, Purdue University, West Lafayette, IN 47907-1395, USA, santos@fcaglp.unlp.edu.ar
Etude de la pyrolyse de composés lignocellulosiques et modélisation de ce processus

L’etude de la pyrolyse de composes lignocellulosiques s’avere importante pour une meilleure comprehension des procedes de conversion thermochimiques de la biomasse. L’etude experimentale de la pyrolyse de cellulose revele que le rendement en residu solide carbone depend aussi bien des parametres operatoires utilises que des caracteristiques geometriques de l’echantillon. Ces resultats experimentaux sont elargis a des materiaux naturels, et notamment la lignine et l’hemicellulose. Cette etude est completee en identifiant les phenomenes thermiques intervenant lors de ce processus par analyse thermique differentielle des constituants de la biomasse. L’ensemble de ces resultats permet d’effectuer une modelisation de ce processus predisant le profil de temperature ainsi que la conversion de la reaction de pyrolyse d’un echantillon cylindrique de bois naturel (hetre, chene). Enfin, un exemple de valorisation du materiau pyrolyse, a savoir la production de charbons actifs est presentee.
Accounting and reporting of enterprises in the conditions of informatization of the economy

Summary. The article deals with the main aspects of Informatization of society and the impact of the latest information technologies on the domestic economy. Different interpretations of the concept of «information» and its influence on effective management decisions are analyzed. Various types of activity in accounting and reporting of enterprises in the conditions of global Informatization are investigated and it is proposed to use a new type of activity «in-formation activity». It is proved that in order to form a financial result from information activities, it is necessary to introduce new accounting accounts «information income» and «information expenses».
Evolution of CSR in the changing scenario: A review

The present paper is an attempt to collect and review important and selected literatures, both conceptual and analytical in nature that outline the significance of strategy and its best practices on Corporate Social Responsibility (CSR) to achieve inclusive growth, which aids to the overall efficiency of different corporate houses that are operating in the most competitive global business environment. Many researchers have conducted studies on how CSR contributed to the India’s sustainable growth. The review part pertaining to inclusive growth discuss about the institutional mechanism and practices in managing the CSR related activities in different sectors of society. In the current paper a significant number of research works conducted mostly in India, and a few more from global were discussed of numerous past literatures and investigations of their coherent linkage with the theme of how evolution of CSR playing a pivotal role in achieving economic and sustainable growth.
Effects of α-linolenic acid calcium on lipid metabolism of mice with hyperlipidemia.

The effect of calcium α-linolenic acid (Ca-ALA) on lipid metabolism of mice with hyperlipidemia was studied. The KunMing-strain male mice were divided into normal, model, low-dose, middle-dose and high-dose groups. The hyperlipidemia model was established by feeding mice with high fat feed. 7 Days later, the mice of the low-dose, middle-dose and high-dose groups were feed with high fat feeds containing 0.095%,0.190% and 0.380% of Ca-ALA, respectively. 6 Weeks later, the effects of Ca-ALA on weight, liver index and serum lipid were observed. The results showed that Ca-ALA could significantly reduce weight and liver index of the mice, significantly reduce serum TC, TG and LDL-C lever also. All these results indicated that Ca-ALA had significantly effect on regulation of lipid metabolism.
Relation of homeostasis model of insulin resistance and body mass index with cardiac repolarization inhomogeneity in overweight and obese patients

In obese individuals, asymptomatic minimal myocardial dysfunction can be encountered even in the absence of structural of functional cardiac alterations. Novel electrocardiographic (ECG) parameters are used to predict arrhythmias related to this situation. We aimed to evaluate body mass index (BMI) and homeostasis model of insulin resistance (HOMA-IR) levels and investigate their relationship with the novel ECG parameters. The study was conducted with 250 individuals in five groups (normoweight, overweight, class I obese, class II obese, and class III obese) each including 50 subjects. The ECGs of the individuals were retrospectively reviewed. Corrected QT (QTc), QTc dispersion (QTcd), Tpeak-Tend (Tp-e) interval, Tp-e dispersion (Tp-ed), and Tp-e/QT and Tp-e/QTc ratios were calculated and their relationship with BMI and HOMA-IR was investigated. ECG parameters indicating ventricular repolarization inhomogeneity were significantly different in overweight individuals compared with the normoweight individuals. Comparing overweight and obese subjects, it was determined that QTc, QTcd and Tp-ed parameters were significantly associated with obesity and showed positive correlations with BMI and HOMA-IR. There was a positive relationship of BMI and HOMA-IR with the novel parameters indicating ventricular repolarization abnormality. Novel and simple ECG parameters including QTc, QTcd, and Tp-ed might be beneficial in monitoring of such patients for critical cardiac events, such as ventricular tachycardia or sudden cardiac death.
Molecular mimicry in deoxy-nucleotide catalysis: the structure of Escherichia coli dGTPase reveals the molecular basis of dGTP selectivity: New structural methods offer insight on dGTPases

Deoxynucleotide triphosphate triphosphyohydrolyases (dNTPases) play a critical role in cellular survival and DNA replication through the proper maintenance of cellular dNTP pools by hydrolyzing dNTPs into deoxynucleosides and inorganic triphosphate (PPPi). While the vast majority of these enzymes display broad activity towards canonical dNTPs, exemplified by Sterile Alpha Motif (SAM) and Histidine-aspartate (HD) domain-containing protein 1 (SAMHD1), which blocks reverse transcription of retroviruses in macrophages by maintaining dNTP pools at low levels, Escherichia coli (Ec)-dGTPase is the only known enzyme that specifically hydrolyzes dGTP. However, the mechanism behind dGTP selectivity is unclear. Here we present the free-, ligand (dGTP)- and inhibitor (GTP)-bound structures of hexameric E. coli dGTPase. To obtain these structures, we applied UV-fluorescence microscopy, video analysis and highly automated goniometer-based instrumentation to map and rapidly position individual crystals randomly-located on fixed target holders, resulting in the highest indexing-rates observed for a serial femtosecond crystallography (SFX) experiment. The structure features a highly dynamic active site where conformational changes are coupled to substrate (dGTP), but not inhibitor binding, since GTP locks dGTPase in its apo form. Moreover, despite no sequence homology, dGTPase and SAMHD1 share similar active site and HD motif architectures; however, dGTPase residues at the end of the substrate-binding pocket mimic Watson Crick interactions providing Guanine base specificity, while a 7 Å cleft separates SAMHD1 residues from dNTP bases, abolishing nucleotide-type discrimination. Furthermore, the structures sheds light into the mechanism by which long distance binding (25 Å) of single stranded DNA in an allosteric site primes the active site by conformationally “opening” a tyrosine gate allowing enhanced substrate binding. Significance Statement dNTPases play a critical role in cellular survival through maintenance of cellular dNTP. While dNTPases display activity towards dNTPs, such as SAMHD1 –which blocks reverse transcription of HIV-1 in macrophages– Escherichia coli (Ec)-dGTPase is the only known enzyme that specifically hydrolyzes dGTP. Here we use novel free electron laser data collection to shed light into the mechanisms of (Ec)-dGTPase selectivity. The structure features a dynamic active site where conformational changes are coupled to dGTP binding. Moreover, despite no sequence homology between (Ec)-dGTPase and SAMHD1, both enzymes share similar active site architectures; however, dGTPase residues at the end of the substrate-binding pocket provide dGTP specificity, while a 7 Å cleft separates SAMHD1 residues from dNTP.
Contribution of FEF to Attentional Periodicity during Visual Search: A TMS Study

Abstract Visual search, looking for a target embedded among distractors, has long been used to study attention. Current theories postulate a two-stage process in which early visual areas perform feature extraction, whereas higher-order regions perform attentional selection. Such a model implies iterative communication between low- and high-level regions to sequentially select candidate targets in the array, focus attention on these elements, and eventually permit target recognition. This leads to two independent predictions: (1) high-level, attentional regions and (2) early visual regions should both be involved periodically during the search. Here, we used transcranial magnetic stimulation (TMS) applied over the frontal eye field (FEF) in humans, known to be involved in attentional selection, at various delays while observers performed a difficult, attentional search task. We observed a periodic pattern of interference at ∼6 Hz (theta) suggesting that the FEF is periodically involved during this difficult search task. We further compared this result with two previous studies (Dugué et al., 2011, 2015a) in which a similar TMS procedure was applied over the early visual cortex (V1) while observers performed the same task. This analysis revealed the same pattern of interference, i.e., V1 is periodically involved during this difficult search task, at the theta frequency. Past V1 evidence reappraised for this paper, together with our current FEF results, confirm both of our independent predictions, and suggest that difficult search is supported by low- and high-level regions, each involved periodically at the theta frequency.
Theoretical Analysis of Open Spherical Microphone Arrays for Acoustic Intensity Measurements

Acoustic intensity is a vectorial measure of acoustic energy flow through a given region of interest. Three dimensional measurement of acoustic intensity requires special microphone array configurations. This article provides a theoretical analysis of open spherical microphone arrays for the 3-D measurement of acoustic intensity. The calculation of the pressure and the particle velocity components of the sound field inside a closed volume is expressed using the Kirchhoff-Helmholtz integral equation. The conditions which simplify the calculation are identified. This calculation is then constrained to a finite set of microphones positioned at prescribed points on a sphere. Several open spherical array topologies are proposed. Their magnitude and directional errors and measurement bandwidths are investigated via numerical simulations. A comparison with conventional open-sphere 3-D intensity probes is presented.
Preliminary Study of the Location of the Her2 Proteins by Molecular Imaging (MALDI-IMS) in a Histological Section of the Breast

Subsequent staining of the slice with eosin/hematoxylin indicates that the peptide signal is in a cell proliferation zone in the tissue. Figure 1: (A) Peptide identification of Her2 by LC/MS (715.4 Daltons) (B) Molecular imaging of the 715.4 peptide distribution of Her2 protein in breast biopsy tissue (C) Subsequent staining of the EH slice. Image 1 mm (D) Eosyn Hematoxylin image with microscope (90 μm)
Spatial Autocorrelation Function of Wave Functions in a Chaotic Microwave Billiard

In the present diploma thesis an experimental test of the theoretical prediction about the asymptotical behavior of a spatial autocorrelation function for quantum systems, the classical counterpart of which is ergodic, has been carried out. The basis of the experimental verification is the analogy between the Schrödinger equation for a point like-particle confined in a hard-wall potential and the Helmholtz equation for a quasi two-dimensional microwave resonator. The test was made for the eigenfunctions of a microwave Sinai billiard. For the experimental determination of the electromagnetic field intensity, which corresponds to the eigenfunctions of the microwave resonator, the perturbation body technique was used. For the extraction of the electrical field strength from the electromagnetic field intensity a field reconstruction procedure was specially developed within the framework of the diploma thesis. Good agreement with theory was obtained for an averaged over all directions of separating vector autocorrelation function. The autocorrelation function for different direction of separating vectors shows a more complicated behavior than predicted.
Screening of phytochemical compounds and mosquito larvicidal activity of Allmania nodiflora (L.) R.Br.ex Wight (Amaranthaceae)

In the present investigation phytochcmical analysis and larvicidal activity of Allmania nodiflora. were screened against Aedes aegypti in the phytochemical analysis of the petroleum ether and ethanol extract of A. nodiflora revealed the presence of alkaloids, flavanoids, saponins, glycosides, steroids. The phenol and tannin were absent in petroleum ether extract in ethanolic extract. The tannins were present and absent in petroleum ether extract. In GCMS analysis 9 bioactive phytochemical compounds were identified in the ethanolic extract of A. nodiflora. The extract were subjected for screening of larvicidal activity against Aedes aegypti at the concentration of (2%, 4%, 8%, 10%, 15%, 20%) were analyzed the highest mortality was observed after 96 hours in ethanolic extract. Lowest mortality was observed in petroleum ether extract 24hours.
VORTEX SUPPRESSION FOR DIFFERENT BOUNDED SHEAR FLOWS PAST A ROTARY OSCILLATING CIRCULAR CYLINDER

This work investigates the vortex suppression by a rotary oscillating circular cylinder in twodimensional laminar shear flows. Two kinds of shear flows were employed in the present study; they are the Poiseuille and Couette flows. We carried out a series of computations with different combinations of the rotary frequency and the peak rotation speed of the cylinder at medium and large blockage ratios.
Efficacy of laparoscopy for acute Cholecystitis: A comparative study

Background: Laparoscopic cholecystectomy (LC) represents a significant change in the management of gallbladder disease and it is the most commonly performed operation of the digestive tract. It is considered as the gold standard treatment for Cholelithiasis. For acute Cholecystitis, however, the use of laparoscopic cholecystectomy has been controversial up until recently, because of the high open conversion rate and the high incidence of postoperative complications.Aim of the study: To study efficacy of laparoscopy for acute Cholecystitis.Materials and methods: For the study, we retrospectively reviewed the medical records of patients aged 30-65 years with acute Cholecystitis who underwent Laparoscopic cholecystectomy (LC) and were compared patients who underwent open cholecystectomy (OC). A total of 120 patients (70 for LC and 50 for OC) were reviewed.Results: Our study group comprised of 120 total patients. 70 had undergone LC and 50 had undergone OC. On comparing the demographics of the patients, the results were found to be statistically non-significant for all the parameters. We observed that mean operative time for LC was 49.69 min and for OC was 62.36 min.Conclusion: Within the limitations of the present study, it can be concluded that laparoscopic cholecystectomy has equal efficacy for acute Cholecystitis patients as compared to open cholecystectomy.
The Influence of the Size, Shape and Character of Nanofillers on Functional Properties of Polyurethane Elastomers

The chapter is aimed at polyurethane-inorganic nanofiller nanocomposite preparation and characterization. Polyurethane (PU) matrix is formed from aliphatic polycarbonatebased diol (MW ca. 2000; macrodiol, MD), hexamethylene diisocyanate (HDI) and butane 1,4-diol (BD; used as the chain extender). One-step procedure for PU and PU nanoomposite preparation was used. Equal ratio of MD-to-BD hydroxyl groups was used in the synthesis. PU and PU nanocomposites contain 81-82 wt. % of soft (polycarbonatebased) segments and 18 wt. % of hard segments (HDI-BD product). Pure PU matrix is distinguished by (i) thermoplastic character, (ii) high degree of the phase separation of soft and hard segments; (iii) low crystallinity (< 10%) and (iv) very good mechanical and thermomechanical properties, resulting from tensile tests and dynamic mechanical thermal analysis. Silica nanoparticles differing in size (7 to 40 nm) were used as the nanofiller in the concentration 1 wt. % in the PU nanocomposite. The influence of the size and character of the silica nanoparticles on the internal particle arrangement in PU matrix and on functional, e.g., mechanical, surface and barrier properties of PU nanocomposites was discussed, and compared with related nanocomposites containing layered nanoparticles (bentonite), studied previously.
Chemistry, traditional uses and pharmacological effects of Centella asiatica (L.): A review

Centella asiatica (L.) is a valuable medicinal herb mainly distributed to Southeast Asian regions. Current study attempts to provide detailed information on morphology, chemistry, therapeutic uses, side effects and current herb research perspectives. This perennial creeper has been traditionally used for rheumatism, indigestion, diabetes, dysentery, fever, fractures, hepatitis, jaundice, constipation, wounds, and eye problems. Its medicinal values are attributed to the presence of tri-terpenes, carotenoids, glycosides, flavonoids, alkaloids, volatile and fatty oils. In vivo and in vitro investigations have demonstrated a number of biological effects such as wound healing, antiulcer, anti-leprotic, anti-tubercular, anti-cancer, memory enhancing, and immune-modulatory effects. However, absence of detailed scientific approach regarding to Centella asiatica health benefits hinders the perception of its benefits to develop new drugs. Moreover, composition of bioactive constituents is greatly affected by various biotic and abiotic factors that must be studied in detail to maximize the utilization of plant.
MAS212 Assignment #2: The damped driven pendulum

In this assignment we study the motion of a rigid pendulum of length ` and mass m, shown in Fig. 1, using both analytical and numerical methods. The state of the system is described by the angle θ of the rod to the vertical, with θ = 0 corresponding to the equilibrium position where the bob is directly below the pivot. The bob can ‘swing over the top’. Early time-keeping devices, such as grandfather clocks, used pendulums to mark time, relying on their regular oscillations. At small amplitudes (θ 1), the motion is regular with a fixed period. However, the driven damped oscillator, studied in Sec. 3, is one of the simplest systems to show chaotic dynamics [1], that is, irregular and unpredictable motion with an exponential sensitivity to initial conditions [2].
Smartphone apps: A state-of-the-art approach for oral health education.

While there is an ever increasing use of smartphones in recent times, cellular phone based mobile applications (apps) are hardly used by the public to improve oral health. Hence, this cross-sectional study was conducted to evaluate the features of the current oral health education smart phone apps pertaining to dental patients. Materials and Methods: Oral health terms were queried in the online app stores. Among the apps found, all patient-related apps were listed and categorized. The apps were assessed for type, cost, rating, average number of downloads, involvement of dental professional in their development, target group, local or global applicability, the benefits and drawbacks of the apps and user reviews. Results: A total of 146 oral health apps for patient use were found, with the most common being about techniques for oral hygiene (33.5%) and tooth brushing timers (25.3%). The majority of apps (69.2%) were available for downloading for no cost. ‘Happy teeth, healthy kids app’, ‘Disney Magic timer’ and ‘Happy Kids timer’ were the most downloaded apps. Conclusion: A considerable number of mobile apps are currently available for patients to help them in maintaining oral health, though most of them are brushing timers or demonstrate oral hygiene techniques.
Medication assisted treatment with buprenorphine/naloxone or methadone: Comparitive outcomes in patients with an opioid addiction

A clinical decision report appraising Hser YI, Evans E, Huang D, et al. Long‐term outcomes after randomization to buprenorphine/naloxone versus methadone in a multi‐site trial. Addiction. 2016;111(4):695-705. https://doi.org/10.1111/add.13238 for a patient with addiction to prescription opioids.