Miracle-dz/UniFAR-FTUs huggingface dataset:
O índice de sustentabilidade empresarial e a percepção do investidor: um estudo das empresas entrantes no índice nos anos de 2011 a 2013

Segundo responsaveis pelo ISE (Indice de Sustentabilidade Empresarial), as aplicacoes denominadas investimentos socialmente responsaveis, consideram que empresas sustentaveis geram valor para o acionista no longo prazo, pois estao mais preparadas para enfrentar riscos economicos, sociais e ambientais. Essa demanda veio se fortalecendo ao longo do tempo e hoje e amplamente atendida por varios instrumentos financeiros no mercado nacional e internacional. Nesse contexto, este trabalho analisou a entrada das empresas, de 2011 a 2013, na carteira de empresas responsaveis socialmente (Indice de Sustentabilidade Empresarial). Avaliou o conjunto de indicativos de preco das acoes antes e depois de entrada no ISE. Comparou o desempenho do mercado de acoes diretamente com periodo anterior e um posterior ao anuncio de entrada nesse indice. O objetivo, atraves do estudo de eventos, foi avaliar se o investidor agregou valor ou nao ao seu patrimonio por decisao dos gestores das companhias quando da entrada no indice de sustentabilidade. Dentro desse contexto, avaliou tambem se o fato de comunicar ao mercado que sao empresas socialmente corretas foi capaz de fazer valer essa percepcao e se os acionistas dessas empresas tiverem retorno acima do normal por esse evento. Os resultados observados neste trabalho (na media) trazem indicios de que o mercado avalia positivamente os esforcos de sustentabilidade e esta disposto a remunerar melhor por isso, porem esse patamar nao se mantem no tempo. Ja para o ano de 2013 observa-se um fato novo, nao ocorrido ate o momento, que sao indicios de uma virada na percepcao do mercado quanto aos esforcos de sustentabilidade das empresas. Nesse ano, os retornos anormais (para empresa WEG) continuaram apos o momento do anuncio da entrada no indice. Esse fato pode indicar que o fato publico teria sido capaz de maximizar a riqueza do acionista
A new method to improve temporal resolution of remote sensing imaging

High-Resolution has become the vital trend of remote sensing imaging, but there are few researches on high temporal resolution at present. We illustrate the importance of high temporal resolution and propose a new method to improve it. Combining with different scene, we analyze the track of moving object and solve motion parameters of target, then construct high temporal resolution series images. Experiment shows that our models can effectively improve temporal resolution.
High Throughput architecture for OCTAGON Network on Chip

High Throughput Octagon architecture to achieve high performance Networks on Chip (NoC) is proposed. The architecture increases the throughput of the network by 17% while preserving the average latency. The area of High Throughput OCTAGON switch is decreased by 18% as compared to OCTAGON switch. The total metal resources required to implement High Throughput OCTAGON design is increased by 8% as compared to the total metal resources required to implement OCTAGON design. The extra power consumption required to achieve the proposed architecture is 2% of the total power consumption of the OCTAGON architecture.
Chromosomal polymorphism in mammals: an evolutionary perspective

Although chromosome rearrangements (CRs) are central to studies of genome evolution, our understanding of the evolutionary consequences of the early stages of karyotypic differentiation (i.e. polymorphism), especially the non‐meiotic impacts, is surprisingly limited. We review the available data on chromosomal polymorphisms in mammals so as to identify taxa that hold promise for developing a more comprehensive understanding of chromosomal change. In doing so, we address several key questions: (i) to what extent are mammalian karyotypes polymorphic, and what types of rearrangements are principally involved? (ii) Are some mammalian lineages more prone to chromosomal polymorphism than others? More specifically, do (karyotypically) polymorphic mammalian species belong to lineages that are also characterized by past, extensive karyotype repatterning? (iii) How long can chromosomal polymorphisms persist in mammals? We discuss the evolutionary implications of these questions and propose several research avenues that may shed light on the role of chromosome change in the diversification of mammalian populations and species.
The results of 21-year experience of treating anal squamous cell carcinomas.

OBJECTIVE Anal squamous cell carcinomas are one of the rare cancer types. Due to the developments in the past 35 years, surgery is no longer the first treatment of choice. The aim of this study was to retrospectively examine the outcomes of 24 patients treated in a single center in the last 21 years in terms of applied treatment, local relapse, distant metastasis, post-treatment complications, and survival. MATERIAL AND METHODS Data obtained from 24 anal squamous cell carcinoma patients, who were treated in Ankara Oncology Research and Education Hospital between 1990 and 2010, were retrospectively evaluated. RESULTS Of the 24 patients, 16 had anal canal squamous cell carcinoma and eight had perianal squamous cell carcinoma. All of the patients with anal canal squamous cell carcinoma (n=16) received chemoradiotherapy. Three of these patients who did not respond to treatment, underwent abdominoperineal resection. The patients with perianal squamous cell tumors were treated by local excision. During the follow -ups, seven patients experienced local relapse, and one patient had distant organ metastasis. Only one patient died. Five-year disease free survival rate was found as 66%. CONCLUSION Our findings suggest that the first alternative in the treatment of anal squamous cell tumors should be chemoradiotherapy; and surgery seems to be the appropriate approach for the non-responsive and relapsing cases.
Households' Capital Account: Investment, Gross and Net Savings in the NIPA

We recreate the NIPA adjustments pioneered by Ruggles and Ruggles (1992) for the period 1947-2012 and reconrm their results: household net lending to other sectors is counter-cyclical and is a small fraction private rms' gross capital formation (GCF). To test the causal role of household Net Savings in terms of GCF and GDP growth, a VEC model is estimated. The VECM is cointegrated stationary for the three annual time series, but exogeneity testing shows household Net Savings is exogenous. We argue this is evidence of inter-secotral investment demand as driving feature of growth.
Peripheral nociceptive effects of alpha 2-adrenergic receptor agonists in the rat.

We have previously shown that norepinephrine can produce hyperalgesia via an alpha 2-adrenergic receptor mechanism. The alpha 2-adrenergic receptor agonist clonidine has, however, also been shown to produce peripheral analgesia. In view of the multiple alpha 2-subtypes currently known (i.e. alpha 2A, alpha 2B and alpha 2C), we evaluate the alpha 2-receptor subtypes mediating norepinephrine-induced peripheral hyperalgesia and clonidine analgesia. Norepinephrine and the alpha 2-adrenergic agonists clonidine and UK 14,304 (1-1000 ng), when co-injected with the calcium ionophore A23187 (1000 ng) produced dose-dependent hyperalgesia in the Randall-Selitto paw withdrawal test. Norepinephrine (100 ng) hyperalgesia was dose-dependently antagonized by alpha 2-adrenergic receptor antagonists. From the estimated ID50, the rank order of potency was: SK&F 104856 (alpha 2B) approximately imiloxan (alpha 2B) > rauwolscine (alpha 2C) >> BRL 44408 (alpha 2A). Norepinephrine hyperalgesia was not significantly affected by pertussis-toxin treatment. Prostaglandin E2 (100 ng) hyperalgesia was inhibited dose-dependently, by clonidine and UK 14,304. Rauwolscine was more potent in reversing the inhibitory effect of clonidine on prostaglandin E2 than imiloxan while BRL 44408 was ineffective. The inhibitory effect of clonidine on prostaglandin E2 hyperalgesia was reversed by pertussis toxin. These data suggest that alpha 2B-subtype receptors mediate (norepinephrine hyperalgesia while the antinociceptive effect of alpha 2-agonist is mediated by the alpha 2C-subtype receptor. Differential coupling of these receptor subtypes to second messenger systems and location on different cell types in the rat paw may explain, at least in part, their differential responses to alpha 2-agonist stimulation, leading to hyperalgesia and analgesia.
Improved prognosis of thoracic aortic aneurysms: a population-based study.

CONTEXT Managing thoracic aortic aneurysms identified incidentally by increased use of computed tomography, echocardiography, and magnetic resonance imaging is problematic, especially in the elderly. OBJECTIVE To ascertain whether the previously reported poor prognosis for individuals with thoracic aortic aneurysms has changed with better medical therapies and improved surgical techniques that can now be applied to aneurysm management. DESIGN Population-based cohort study. SETTING AND PATIENTS All 133 patients with the diagnosis of degenerative thoracic aortic aneurysms among Olmsted County, Minnesota, residents between 1980 and 1994 compared with a previously reported cohort of similar patients between 1951 and 1980. MAIN OUTCOME MEASURES The primary clinical end points were incidence, cumulative rupture risk, rupture risk as a function of aneurysm size, and survival. RESULTS In contrast to abdominal aortic aneurysms, for which men are affected predominately, 51% of thoracic aortic aneurysms were identified in women who were considerably older at recognition than men (mean age, 75.9 vs 62.8 years, respectively; P= .01). The overall incidence rate of 10.4 per 100000 person-years (95% confidence interval [CI], 8.6-12.2) between 1980 and 1994 was more than 3-fold higher than the rate from 1951 to 1980. The cumulative risk of rupture was 20% after 5 years. Seventy-nine percent of ruptures occurred in women (P= .01). The 5-year risk of rupture as a function of aneurysm size at recognition was 0% for aneurysms less than 4 cm in diameter, 16% (95% CI, 4%-28%) for those 4 to 5.9 cm, and 31% (95% CI, 5%-56%) for aneurysms 6 cm or more. Overall 5-year survival improved to 56% (95% CI, 48%-66%) between 1980 and 1994 compared with only 19% between 1951 and 1980 (P<.01). CONCLUSIONS In this population, elderly women represent an increasing portion of all patients with clinically recognized thoracic aortic aneurysms and constitute the majority of patients whose aneurysm eventually ruptures. Overall survival for thoracic aortic aneurysms has improved significantly in the past 15 years.
mRNA from frog corneal epithelium increases water permeability in Xenopus oocytes.

PURPOSE To investigate the existence of a water channel in the frog corneal epithelium by studying the osmotic water permeability (Pf) of Xenopus oocytes expressing the mRNA message from frog corneal epithelium. METHODS Total RNA was obtained from corneal epithelium by a single-step phase separation method, and poly A+ RNA was isolated using oligo-dT columns. This mRNA was injected into the oocytes. After a 48-hour incubation, oocyte volume changes elicited by a hypoosmotic solution were measured with a computerized video system. RESULTS Oocytes injected with 50 nl mRNA (1 microgram/microliter) showed a significant increase in Pf compared to water-injected controls (8.4 +/- 1.5 to 17.5 +/- 1.9 cm.sec-1 x 10(-4), P < 0.005). mRNA-injected oocytes exposed to a higher external [Cl-] showed a heightened permeability. Furthermore, Pf of oocytes exposed to a solution containing the recognized water-channel blocker HgCl2 was significantly lower than the Pf of mRNA-injected oocytes not exposed to HgCl2. CONCLUSIONS Evidence was found for a water channel in the frog corneal epithelium because oocytes injected with the epithelial mRNA manifested increased water permeability. The increase in water permeability was larger in the presence of external Cl- and was inhibited by HgCl2. This finding correlates with measurements of Pf in the intact epithelium in which apical Cl- induced an increase in transepithelial water permeability prevented by HgCl2.
E2-p7 Region of the Bovine Viral Diarrhea Virus Polyprotein: Processing and Functional Studies

ABSTRACT The genes encoding pestivirus E2 and NS2-3 are separated by a sequence that encodes a small hydrophobic polypeptide with an apparent molecular mass of 6 to 7 kDa (p7). It has been shown that cleavage between E2 and p7 is incomplete, resulting in proteins E2-p7, E2, and p7. We found no precursor-product relationship between E2-p7 and E2, which indicates a stable nature of E2-p7. To study the function of the E2-p7 region of the polyprotein, mutations were introduced into an infectious cDNA of bovine viral diarrhea virus (BVDV). When cleavage between E2 and p7 was abolished, viral RNA replication occurred; however, no infectious virus could be recovered. A corresponding result was obtained with a construct encompassing a large in-frame deletion of p7. To prevent synthesis of E2-p7, a translational stop codon was introduced after the last codon of the E2 gene and an internal ribosome entry site element followed by a signal peptide coding sequence was inserted upstream of the p7 gene. Transfection of RNA transcribed from the bicistronic construct led to the release of infectious virus particles. Thus, synthesis of E2-p7 is not essential for the generation of infectious virions. Cell lines constitutively expressing BVDV p7 and/or E2 were generated for complementation studies. Transfection of BVDV RNAs with point mutations or a deletion in the E2-p7 region into the complementing cell lines led to the generation of infectious virions. According to our studies, p7 as well as E2 can be complemented in trans.
Patterns of life visual analytics suite for analyzing GPS movement patterns

We developed the Patterns of Life (PoL) suite for the IEEE VAST 2014 Mini-Challenge 2. The suite comprises PoL Atlas for visualising movement and transactions spatiotemporally, PoL Classifier for classifying locations and identifying trips, and PoL Location Timeline, for visualising where time is spent.
OPILAND : identification de la perception des territoires par la fouille de texte

De nombreux travaux ont ete realises en extraction d'informations et plus particulierement en fouille de donnees d'opinions dans des contextes specifiques tels que les critiques de films, les evaluations de produits commerciaux, les discours electoraux. Dans le cadre du projet SENTERRITOIRE, nous nous posons la question de l'adequation de ces methodes pour des documents associes a l'amenagement des territoires. Ces documents renferment differents types d'informations se rapportant a des acteurs, des opinions, des informations geographiques, et tout autre aspect lie plus generalement a la notion de territoire. Cependant, il est extremement difficile d'identifier puis de lier les opinions a ces informations. Apres avoir souligne les limites des propositions actuelles et les verrous souleves par les donnees textuelles associees, nous proposons la me- thode semi-automatique nommee OPILAND (OPinion mIning from LAND-use planning documents) combinant une chaine de Traitement Automatique du Lan- gage Naturel et des techniques de Fouilles de Textes pour (1) detecter les entites nommees de type lieu et organisation, (2) construire un vocabulaire d'opinions relatif au domaine d'application, et (3) identifier les opinions relatives aux entites nommees traitees. Les experimentations sont menees sur des donnees du bassin de Thau (France), puis appliquees sur trois corpus relatifs a d'autres domaines afin de mettre en avant la genericite de notre approche.
Experimental Chick Colonization by Campylobacter jejuni

Campylobacter jejuni is commonly isolated from animals, including rodents, farm animals, and especially birds. The most common route of infection for humans is through the ingestion of contaminated chicken. Although C. jejuni commonly inhabits a number of animals, it does so asymptomatically. Many animals have been explored for use in pathogenic models; however, the most commonly used and established animal model is the chick colonization model described in this unit. Curr. Protoc. Microbiol. 11:8A.3. 1‐8A.3. 7. © 2008 by John Wiley & Sons, Inc.
LDA fusing of acoustic and prosodic features: Application to speaker recognition

This paper assesses two popular speaker features prosodic and cepstral coefficient. We compare the performance of individual features and features combined via SFS and LDA. The identification process can be performed both in the temporal and cepstral domains. The result show that the reduced sets of the composite LDA feature allow more robust estimates for the model parameters and improve the Recognition Rate (RR), as well as reducing the size which is crucial for real-time speaker recognition application using low-resource devices.
Stochastic Learning of Nonstationary Kernels for Natural Language Modeling

Natural language processing often involves computations with semantic or syntactic graphs to facilitate sophisticated reasoning based on structural relationships. While convolution kernels provide a powerful tool for comparing graph structure based on node (word) level relationships, they are difficult to customize and can be computationally expensive. We propose a generalization of convolution kernels, with a nonstationary model, for better expressibility of natural languages in supervised settings. For a scalable learning of the parameters introduced with our model, we propose a novel algorithm that leverages stochastic sampling on k-nearest neighbor graphs, along with approximations based on locality-sensitive hashing. We demonstrate the advantages of our approach on a challenging real-world (structured inference) problem of automatically extracting biological models from the text of scientific papers.
The distribution of Aedes aegypti (diptera, culicidae) in eight selected parks of Lahore, using oviposition traps during rainy season.

OBJECTIVE To investigate the seasonal distribution of immature habitat of Aedes aegypti mosquito species and its association with environmental and climatic conditions. METHODS This descriptive study was conducted in eight parks in Lahore, Pakistan, over three years from 2011 to 2013.A total of 2,496 ovitraps were placed in environmentally different conditions near water channels, thick vegetation cover/shades, clean/unclean sites and places where there was lot of human activity. Each trap was monitored weekly in early rainy, late rainy, early post-rainy and late post-rainy seasons of each of the three years to determine the presence of Aedes aegypti larvae by measuring ovitrap index. SPSS19 was used for data analysis. RESULTS The value for ovitrap index was found highest in late rainy season (20.83). High association was observed with environmental conditions (p<0.05) as this index was high in micro-habitats close to water channels, shades and residences. The association of ovitrap index with water channel, vegetation cover, cleanliness and human activity was significant in all four seasons (p=-0.000). With temperature, this association was significant only in early post-rainy (p=-0.000) and late post-rainy seasons (p=0.024). With humidity, it was significant in early post-rainy and late post-rainy seasons (p=-0.000 and p=0.024) while with rainfall, the association was significant in all seasons (p=0.000). CONCLUSIONS Abundance and occurrence frequency of Aedes aegypti had a positive association with deteriorating environmental and seasonal climatic conditions.
A labeled-line for cold from the periphery to the parabrachial nucleus

Spinal projection neurons are a major pathway through which somatic stimuli are conveyed to the brain. However, the manner in which this information is coded is poorly understood. Here, we report the identification of a modality-selective spinoparabrachial (SPB) neuron subtype with unique properties. Specifically, we find that cold-selective SPB neurons are differentiated by selective afferent input, reduced neuropeptide sensitivity, distinct physiological properties, small soma size, and low basal drive. In addition, optogenetic experiments reveal that cold-selective SPB neurons are distinctive with respect to their connectivity, with little to no input from either Pdyn or Nos1 inhibitory interneurons. Together, these data define a neural substrate supporting a labeled-line for cold from the periphery to the brain.
Interaction of the actin cytoskeleton with microtubules regulates secretory organelle movement near the plasma membrane in human endothelial cells

The role of cytoskeletal elements in regulating transport and docking steps that precede exocytosis of secretory organelles is not well understood. We have used Total Internal Reflection Fluorescence (TIRF) microscopy to visualize the three-dimensional motions of secretory organelles near the plasma membrane in living endothelial cells. Weibel-Palade bodies (WPb), the large tubular storage organelles for von Willebrand factor, were labelled with Rab27a-GFP. By contrast, green fluorescent protein (GFP)-tagged tissue-type plasminogen activator (tPA-GFP) labelled submicron vesicular organelles. Both populations of GFP-labelled organelles underwent stimulated exocytosis. The movement of these morphologically distinct organelles was measured within the evanescent field that penetrated the first 200 nm above the plasma membrane. WPb and tPA-GFP vesicles displayed long-range bidirectional motions and short-range diffusive-like motions. Rotating and oscillating WPb were also observed. TIRF microscopy enabled us to quantify the contribution of actin and microtubules and their associated motors to the organelle motions close to the plasma membrane. Long-range motions, as well as WPb rotations and oscillations, were microtubule-and kinesin-dependent. Disruption of the actin cytoskeleton and inhibition of myosin motors increased the number of long-range motions and, in the case of WPb, their velocity. The actin and microtubules had opposite effects on the mobility of organelles undergoing short-range motions. Actin reduced the mobility and range of motion of both WPb and tPA vesicles, whereas microtubules and kinesin motors increased the mobility of WPb. The results show that the dynamics of endothelial secretory organelles close to the plasma membrane are controlled by the opposing roles of the microtubule and actin cytoskeletal transport systems.
Painful Pseudowinging and Snapping of Scapula due to Subscapular Osteochondroma: A Case Report

Introduction: Osteochondroma or exostosis is most common benign bone tumors. They are usually seen in the metaphyses of long bones with more than 35% of cases affecting the bone around the knee and are seldom found in flat bones like scapula. When present in scapula, they may cause abnormal scapulothoracic movements leading to pain, snapping, and pseudowinging of scapula. Case report: We describe a novel case of osteochondroma arising on the ventral aspect of right scapula in a 16-year-old otherwise healthy female patient causing snapping and pseudowinging of scapula and occasional pain in affected area. X-ray and computed tomography findings were consistent with an abnormal bony mass arising on ventral aspect of superior border of the scapula. The patient was treated with open extraperiosteal resection of the mass with relief of symptoms. The histopathological diagnosis was consistent with osteochondroma with no signs of malignancy. Conclusion: In a patient with winging and snapping of scapula one should be aware of rare diagnosis osteochondroma along with other more common etiology.