Miracle-dz/UniFAR-FTUs huggingface dataset:
An on-chip active decoupling circuit to suppress crosstalk in deep-submicron CMOS mixed-signal SoCs

A decoupling circuit using an operational amplifier is proposed to suppress substrate crosstalk in mixed-signal system-on-chip (SoC) devices. It overcomes the parasitic inductance problem of on-chip capacitor decoupling. The effect of the proposed decoupling circuit is not limited by parasitic fine impedance. A 0.13-/spl mu/m CMOS test chip showed that substrate noise at frequencies from 40 MHz to 1 GHz was incrementally suppressed by sequentially activating three of the proposed circuits in parallel. The power dissipation of each circuit was 3.3 mW at a 1.0-V power supply. The test chip measurement showed that the proposed decoupling reduced crosstalk by 31% at 200 MHz, whereas it was reduced by 4.4% with capacitor decoupling. This 7:1 ratio, or 17 dB, corresponds to the gain of the opamp. Design of the opamp and its feedback loop for active decoupling is simple, making the opamp useful for SoC applications.
Successive Interference Cancellation for Throughput Maximization in Wireless Powered Communication Networks

In wireless powered communication networks (WPCNs), each user node, e.g., wireless powered sensor, is capable of either harvesting energy from a power station or transmitting data to a sink node. In the previous works, time division multiple access (TDMA) is typically used for transmission scheduling in WPCNs, that is, only one node can transmit data in one time slot. The spectrum efficiency is therefore limited by this orthogonality in time-domain scheduling. In this paper, to maximize the throughput in WPCNs, we present a new scheduling approach for energy harvesting and data transmission. Unlike TDMA, we consider that multiple nodes can simultaneously transmit their data in the same time slot, and the signals are separated at the sink node by performing successive interference cancellation (SIC). We formulate the throughput maximization problem as a linear programming problem. For solving the large scale instances, we design an algorithmic framework based on column generation. Numerical results demonstrate that compared to the TDMA based scheduling approach, substantial throughput improvement is achieved by the proposed algorithm.
Effect of High-Flow Nasal Oxygen on Pulmonary Complications and Outcomes After Adult Cardiothoracic Surgery: A Qualitative Review.

IGH-FLOW NASAL OXYGEN (HFNO) therapy delivers low-level, flow-dependent positive airway pressure and may be tolerated better than continuous positive airway pressure (CPAP) or noninvasive bi-level positive airway pressure (BiPAP) and enhance washout of nasopharyngeal deadspace, thus improving oxygenation. 1,2 The apparatus is composed of an air/oxygen blender, an active heated humidifier, a single heated circuit, and a nasal cannula. At the air/ oxygen blender, the inspiratory fraction of oxygen (FIO2) is set from 0.21 to 1.0 at a flow of up to 60 L/min. The gas is heated and humidified with the active humidifier and delivered through the heated circuit. Theoretically, HFNO has a number of advantages over other respiratory support systems, including conventional nasal cannulae, face masks, or CPAP/BiPAP. First, because gas generally is warmed to 371C and completely humidified in HFNO circuits, mucociliary function remains intact and patients report minimal discomfort. Mechanical splinting of the nasopharynx prevents supraglottic collapse and decreases nasopharyngeal resistance, and at 60 L/min HFNO can generate positive end-expiratory pressure (PEEP) of 4 to 7.4 cmH2O, which may counterbalance auto-PEEP and reduce the work of breathing. 3,4 HFNO therapy has been gaining attention as an innovative form of respiratory support in various clinical settings. It is being used increasingly in critically ill patients and gaining favor in the perioperative period. HFNO has been used for multiple indications, including hypoxemic respiratory failure and cardiogenic pulmonary edema, to counterbalance autoPEEP in patients with chronic obstructive airway disease and as prophylactic therapy or treatment of respiratory failure after surgery and extubation. 5 It has been shown to be both safe and noninferior to conventional CPAP in providing prophylactic support to very preterm neonates after extubation. 6 In this same study, the incidence of nasal trauma also was significantly lower in the nasal cannulae group than in the CPAP group. Little clinical experience has been reported on the use of HFNO in the cardiothoracic surgical patient population. Patients undergoing cardiothoracic surgery are at significant risk of postoperative pulmonary complications, and these complications may increase morbidity and mortality and lead to prolonged intensive care unit and hospital length of stay. 7 The incidence of pulmonary complications ranges from 8% to 79% after cardiac surgery and has been reported to be as high as 50% after lung resection surgery. 8 Postoperative pulmonary complications manifest early as arterial hypoxemia, during the later course as pneumonia, and in rare cases also as acute respiratory distress syndrome. 9 The pathogenesis of
Prognostic value of EGFR mutations in surgically resected pathological stage I lung adenocarcinoma

With the advent of the molecular‐targeted therapy, rapid progress has been made in the treatment of advanced or recurrent non‐small‐cell lung cancer (NSCLC). Although surgical complete resection remains the standard and most promising treatment, the clinical significance of epidermal growth factor receptor (EGFR) gene mutations in early‐stage NSCLC remains uncertain.
Osteoprotegerin deficiency and juvenile Paget's disease.

BACKGROUND Juvenile Paget's disease, an autosomal recessive osteopathy, is characterized by rapidly remodeling woven bone, osteopenia, fractures, and progressive skeletal deformity. The molecular basis is not known. Osteoprotegerin deficiency could explain juvenile Paget's disease because osteoprotegerin suppresses bone turnover by functioning as a decoy receptor for osteoclast differentiation factor (also called RANK ligand). METHODS We evaluated two apparently unrelated Navajo patients with juvenile Paget's disease for defects in the gene encoding osteoprotegerin (TNFRSF11B) using polymerase-chain-reaction (PCR) amplification followed by direct sequencing and Southern blotting of genomic DNA. Genetic markers near TNFRSF11B were evaluated by both a PCR method that involved sequence-tagged site-content mapping of a deletion of TNFRSF11B and PCR spanning the DNA break points. RESULTS Both patients had a homozygous deletion of TNFRSF11B, with identical break points, on chromosome 8q24.2. The defect spans approximately 100 kb, but neighboring genes are intact. We found that serum levels of osteoprotegerin and soluble osteoclast differentiation factor were undetectable and markedly increased, respectively. CONCLUSIONS Juvenile Paget's disease can result from osteoprotegerin deficiency caused by homozygous deletion of TNFRSF11B.
Peter’s Transition to Headship: What Can We Learn From His Experience About How to Prepare to Make the Transition From Assistant Principal, or Deputy, to Principal or Head Teacher?

The transition for new head teachers (school principals) can be a difficult and unpredictable one. This article outlines a case of a deputy (assistant principal) in the United Kingdom as he takes up his first headship. We describe some of the challenges involved and prompt readers to consider strategies that could be used and support that may be accessed to negotiate this challenging period. In particular, this illustrative case shows how the lead-in period between appointment and formal assumption of the role can be productively used. This article would be of use to readers aspiring to take on a senior leadership roles. But it would also be relevant for people working at district level and others involved in recruiting, appointing, and supporting senior leaders.
18F-FDG PET/CT in the post-operative monitoring of patients with adrenocortical carcinoma.

CONTEXT The role of (18)F-labeled 2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) in the post-operative monitoring of patients with adrenocortical carcinoma (ACC) is still unclear. OBJECTIVE To assess the accuracy of FDG PET/CT to diagnose ACC recurrence in a real world setting. DESIGN AND METHODS Retrospective evaluation of data of 57 patients with presumed ACC recurrence at CT scan who underwent FDG PET/CT within a median time of 20 days. We compared the results of either FDG PET/CT or CT with a gold standard confirmation of recurrence (positive histopathology report of removed/biopsied lesions or radiological progression of target lesions at follow-up) to assess their diagnostic performance at different body sites to correctly categorize target lesions. We also assessed whether FDG PET/CT findings may be useful to inform the management strategy. RESULTS In 48 patients with confirmed ACC recurrence, we found that FDG PET/CT had lower sensitivity than CT in diagnosing liver and lung recurrences of ACC. FDG PET/CT had higher specificity than CT in categorizing liver lesions. FDG PET/CT had a greater positive likelihood ratio than CT to identify liver and abdominal ACC recurrences. The management strategy was changed based on FDG PET/CT findings in 12 patients (21.1%). CONCLUSIONS The greater sensitivity of CT may be partly expected due the specific inclusion criteria of the study; however, the greater specificity of FDG PET/CT was particularly useful in ruling out suspected ACC recurrences found by CT. Thus, use of FDG PET/CT as a second-line test in the post-operative surveillance of ACC patients following CT finding of a potential recurrence may have a significant impact on patient management.
Grief and the sexual relationship of couples who have experienced a child's death.

In an interview study of the sexual relationship of bereaved parents, 16 of 24 heterosexual couples interviewed after the death of a child reported a break or decline in sexual intercourse. Consistent with social constructivist perspectives, the meanings couples gave to sexual intercourse, the death, and their grief were central in their understanding of the break or decline--e.g., the belief that intercourse was too painful because it was how the child had been made. Meanings were also linked to the continuation or resumption of the intercourse--e.g., that intercourse was life-affirming. Touching, which was defined as sexual by many people interviewed, had consistent meanings across couples--connection, support, and comfort--although couples differed in whether touching increased, decreased, or did not increase enough to satisfy one partner following the death. The meanings that couples used in discussing touching and the decline or break in sexual intercourse were also used in talking about extramarital affairs and grieving during intercourse.
Overview of Methods to Reduce Odorant Emissions from Confinement Swine Buildings

Odors are emitted from a variety of sources in swine production facilities. A large quantity of odorants can be emitted from manure handling and storage facilities. However, swine production buildings can also emit significant levels of odorants. This is especially true if manure is held within the buildings for periods exceeding 4-5 days. Manure also sticks to floors, walls, equipment, and pigs. Feed is often spilled in areas where pigs don’t clean it up. This manure and feed can be around for several days or weeks and release highly objectionable odorants if these organic materials break down under anaerobic conditions. The amount of surface area of these odorant sources can be large and lead to high emissions of odorous gases. To further complicate matters, swine buildings usually have high concentrations of dust in the air and odorants adhere to the dust so the dust can also carry odors out of the buildings (Hoff et al., 1997a).
A Survey of the Key Technology of Software Vulnerability Mining

In the current cyberspace, vulnerability has attracted the widespread attention. This paper briefly introduces the typical software vulnerability mining techniques. Based on the existing research work, this paper puts forward the whole idea of the research on the vulnerability mining technology of software in the future, and then makes some research on some key points and key technologies respectively. In this paper, a brief study of the software vulnerability mining technology is given, which is helpful to carry out the follow-up research work.
Extensive lymphangioma presenting with upper airway obstruction.

OBJECTIVE To describe the results of an outcome survey of 18 cases of pediatric lymphangioma with dyspnea from encroachment on the tongue base, parapharyngeal space, and/or larynx. DESIGN Retrospective review of files from January 1983 to September 1998. SETTING Pediatric otolaryngology departments from 2 referral centers. PATIENTS Eighteen patients were treated. The average age at initial surgery was 22 weeks (median, 5 weeks). All presented with at least unilateral suprahyoid and infrahyoid cavernous (microcystic) lymphangioma. The tongue base was involved in 11 patients, the parapharyngeal space in 12, and the larynx in 8. INTERVENTIONS Neck dissection was performed initially in all patients. Tracheotomy was performed in 9 patients (50%). Macroglossia was treated by V glossoplasty. Parapharyngeal extensions were treated by cervicotomy or endoscopy, and larynx and tongue base extensions by carbon dioxide laser photocoagulation. Supraglottic laryngectomy was performed in 2 patients. MAIN OUTCOME MEASURES Residual disease, decannulation, duration of tracheotomy, and persistent respiratory symptoms. RESULTS The average follow-up was 4 years postoperatively. One postoperative death occurred. Sixteen (94%) of the remaining 17 patients had residual lymphangioma. Eight (89%) of the 9 patients with tracheotomy underwent decannulation (average duration, 22 months). Ten patients had persistent symptoms, and 6 were asymptomatic. CONCLUSIONS Involvement of the upper airway seems to be the determining prognostic factor in extensive lymphangioma. Patients with dyspnea by external compression of cervical lymphangioma on the airway responded well to surgery. Aggressive surgical treatment did not seem to significantly improve the prognosis in patients with intrinsic involvement of the upper airway. The natural evolution of untreated massive lymphangioma has not been documented. Less aggressive, symptomatic therapy may be an alternative to avoid mutilating surgery in patients with intrinsic involvement of the airway.
Miniaturized microstrip antenna array with ultra mutual coupling reduction for wearable MIMO systems

In this paper, a miniaturized microstrip antenna array with two patches is proposed for wearable MIMO systems. The array is designed to resonate at 4.2 GHz and 8.1 GHz for biomedical micro-sensing technology and biomedical diagnostics applications, respectively. In this paper, the use of a diagonal slot on the microstrip patch to reflect the surface current in a direction opposite to that of the neighboring patch. Moreover, the common area of the ground plane, between the two antennas, is augmented with Uniform Compact-Photonic Band Gap (UC-PBG) structures to prevent surface waves. This approach reduces the mutual coupling to −17 dB within a separation distance of 1.4 mm ≈ λ<inf>o</inf>/51, where λ<inf>o</inf> is the wavelength at 4.2 GHz. The microstrip antenna patch is consistent of rectangular part slotted with a diagonal trace and a meander trace which reduces the electrical size of the microstrip patch, when it is printed on substrate of ε<inf>r</inf> = 3.5, to λ<inf>o</inf>/18 × λ<inf>o</inf>/5. The maximum linear dimension of the antenna array is λ<inf>o</inf>/7.2 × λ<inf>o</inf>/4.3 × λ<inf>o</inf>/137. The performance of the array is characterized in terms of S-parameters, broadband gain and correlation spectra as well as the radiation patterns. The proposed antenna array provides bore-sight gain of −15.1 dBi at 4.2 GHz and −7.5 dBi at 8.1 GHz of 54.2 MHz and 81.8 MHz, respectively. The numerical model of the proposed array is simulated based on the Finite Integration Technique (FIT) using the Transient Domain (TD) solver of CST Microwave Studio.
Research on tourism experiencescapes: the journey from art to science

ABSTRACT Researchers have made increasing use of the suffix ‘-scape’ to express the multiple contexts and perspectives that characterize the tourism field. Examples include the terms soundscapes, destinationscapes, landscapes and technoscapes. The present paper explores the application of one such expression – experiencescape – as a potential medium for analyzing various tourism-related experience contexts. The researchers address the persistent adoption of singular investigative perspectives, despite the availability of experimental tracking data that enables more scientific approaches to understanding how experiences are produced, packaged, consumed and staged within environments. To date, there has been no comprehensive review of studies on the evolution and applications of experiencescapes, despite their critical role in forming tourism experiences. This study addresses the gap by discussing the emergence, nature, development and potential of experiencescapes and presents implications for future research. It is found that the experiencescape concept can function both analytically and operationally. It helps to understand, investigate and interpret diverse tourism experiences and provides a basis for developing new or improved experiences.
Nationwide outbreak of Salmonella enterica serotype gives infections in infants in France, linked to infant milk formula, September 2008.

On Thursday 18 September 2008, the hospital of Nantes in west France informed the District Health Office of a case of salmonellosis in an exclusively bottle-fed infant. On Monday morning 22 September, two additional cases of salmonellosis in infants were reported by the hospital of Niort in southwest France. The serotype of the three cases was unknown at that time.
PrP assemblies

The “protein only” hypothesis states that the key phenomenon in prion pathogenesis is the conversion of the host protein (PrPC) into a b-sheet enriched polymeric and pathogenic conformer (PrPSc). However the region of PrP bearing the information for structural transfer is still controversial. In a recent report, we highlighted the role of the C terminal part i.e. the helixes H2 and H3, using mutation approaches on recombinant PrP. The H2H3 was shown to be the minimal region necessary to reproduce the oligomerisation pattern of the full-length protein. The oligomers produced from isolated H2H3 domain presented the same structural characteristics as the oligomers formed from the full-length PrP. Combining other groups’ results, this paper further discusses the relative, direct or indirect role of different PrP regions in assembly. The H2H3 region represents the core of PrP oligomers and fibrils, whereas the N terminus could explain divergences among different aggregates. Finally this review evocates the possibility to separate the domain involved in prion information transference (i.e. prion replication) from the domain bearing the cytotoxicity properties.
The influence of transformational leadership and support for innovation on organizational innovation: from the vocational high school teachers' perspective

The purpose of this study was to investigate the influence of the transformational leadership and support for innovation on organizational innovation. This study used the stratified random sampling method to select 450 teachers from 18 vocational high schools in Taiwan. There were 293 valid questionnaires, and the data were analyzed by using the factor analysis, descriptive statistics, Pearson's correlation coefficients, and multiple regression analysis. Findings of this study suggested that school leaders had to offer the innovative supports such as innovative equipment and financial support available received from the organization could be a better important influence in boosting up organizational innovation.
Updates of Lifetime Costs of Care and Quality-of-Life Estimates for HIV-Infected Persons in the United States: Late Versus Early Diagnosis and Entry Into Care

Background:Lifetime costs of care and quality-of-life estimates for HIV-infected persons depend on the disease stage at which these persons are diagnosed, enter care, and start antiretroviral therapy. Updated estimates were used to analyze the effects of late versus early diagnosis/entry on US lifetime care costs, quality-of-life estimates, and HIV transmissions. Methods:The Progression and Transmission of HIV/AIDS model was used to estimate discounted (3%) lifetime treatment costs ($US 2011) and quality-of-life variables from time of infection for cohorts of 10,000 HIV-infected index patients in 4 categories of CD4 count at diagnosis: (I) ⩽200 cells/&mgr;L, (II) 201–350 cells/&mgr;L, (III) 351–500 cells/&mgr;L, and (IV) 501–900 cells/&mgr;L. It is assumed that index patient diagnoses were uniformly distributed across the CD4 count range in each category and that patients entered care at the time of diagnosis, remained in care, and were eligible to initiate antiretroviral therapy at a CD4 count of 500 cells/&mgr;L. Lifetime transmissions of the index patients were also estimated. Results:Discounted average lifetime costs varied from $253,000 for category I index patients to $402,000 for category IV patients. Discounted quality-adjusted life years lost decreased from 7.95 to 4.45 across these categories, additional years of life expectancy increased from 30.8 to 38.1, and lifetime transmissions decreased from 1.40 to 0.72. Conclusions:Early diagnosis and treatment of HIV infection increases lifetime costs but improves length and quality of life and reduces the number of new infections transmitted by nearly 50%.
Research on coordination of electronic products supply chain based on information sharing

Based on the supply chain information sharing, the study focused on the inventory problem of members in the electronics supply chain. Nowadays, most studies are based on the upstream and downstream supply chain coordination of information sharing between enterprises. This paper studied the influence of information sharing among members of same level in supply chain on the inventory policy. Considering the cost factors caused by information sharing, this paper established a model consisting of two of the same level retailers in the electronic products supply chain. And the relationship between cost and transfer payments of share information was obtained.
Interval algorithm for homophonic coding

It is shown that the idea of the successive refinement of interval partitions, which plays the key role in the interval algorithm for random number generation proposed by Han and Hoshi (see ibid., vol.43, p.599-611, 1997) is also applicable to the homophonic coding. An interval algorithm for homophonic coding is introduced which produces an independent and identically distributed (i.i.d.) sequence with probability p. Lower and upper bounds for the expected codeword length are given. Based on this, an interval algorithm for fixed-to-variable homophonic coding is established. The expected codeword length per source letter converges to H(X)/H(p) in probability as the block length tends to infinity, where H(X) is the entropy rate of the source X. The algorithm is asymptotically optimal. An algorithm for fixed-to-fixed homophonic coding is also established. The decoding error probability tends to zero as the block length tends to infinity. Homophonic coding with cost is generally considered. The expected cost of the codeword per source letter converges to c~H(X)/H(p) in probability as the block length tends to infinity, where, c~ denotes the average cost of a source letter. The main contribution of this paper can be regarded as a novel application of Elias' coding technique to homophonic coding. Intrinsic relations among these algorithms, the interval algorithm for random number generation and the arithmetic code are also discussed.