Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinicopathological features and prognosis factors for survival in elderly patients with pancreatic neuroendocrine tumor

Abstract To investigate the features and prognosis of the elderly patients with pancreatic neuroendocrine tumor (pNET). The patients diagnosed with pNETs between 2004 and 2014 were identified from the Surveillance Epidemiology and End Results database. The ethical approval was waived because the present study was analysis of the data from Surveillance Epidemiology and End Results database. A total of 4608 patients with “one primary only” histologically pNETs were confirmed and 653 were older than 75 years. Cancer-specific survival (CSS) and overall survival (OS) were examined. The elderly patients (≥75 years) have disadvantage in CSS and OS compared with younger cohort. Multivariate logistic regression revealed that the elderly patients have increased poorly differentiated composition, and decreased proportion of Black patients, receipt of surgery, married status, and number of removed lymph node. Multivariate Cox regression analysis demonstrated worse differentiation. Patients of T3–4 and M1 stage were associated with poor CSS, while patients of being female, tumor locating at pancreatic body/tail, receipt of surgery, and being married were associated with better CSS in the elderly patients. Meanwhile, patients with higher histological grade and M1 stage have poor OS, while patients with the characteristics of female, being married, tumor location at pancreatic body/tail and tumor surgery have better OS. Distant metastatic elderly patients underwent primary site surgery had better CSS and OS than the patients without surgery. The elderly patients have increased possibility of poorly differentiated tumor, and decreased proportion of Black patients, surgery of primary site, number of removed lymph node and married status. Worse differentiation and tumor metastasis were independent risk factors for both CSS and OS, while primary tumor located in body/tail of pancreas, female patients, surgery of tumor primary site, and being married were protective factors.
Comparison between video-assisted thoracoscopic lung cancer resection and robot-assisted lung cancer resection

Background: Video-assisted thoracoscopic surgery (VATS) has developed rapidly and a variety of feasible technical methods have been formed. VATS is the main way of lung cancer resection nowadays with minor surgical incision and less bleeding. Robot-assisted thoracic surgery (RATS) is a revolution in surgical procedures and robotic pulmonary resection has been put to use by an increasing quantity of hospitals around the world. However, the widespread adoption of robot-assisted lung cancer resection is controversial. We aimed to evaluate quality metrics of these 2 different approaches of operation by this review and meta-analysis. Methods and Analysis: We will search Medline, Embase, Pubmed, Google Scholar, and the Cochrane Central Register of Controlled Trials for related literature published in any language before February 28, 2019. Propensity score matched comparative studies, prospective cohort studies; randomized controlled trials (RCTs) will be included. If sufficient data are available, we will perform subgroup analysis in different operative types of lung cancer resection. Results: The results of this study will be published in a peer-reviewed journal. Conclusion: To our knowledge, this will be the first time to use meta-analysis to assess quality metrics of video-assisted thoracoscopic lung cancer resection and robot-assisted lung cancer resection. The results of this study will provide more proofs for researchers, clinicians, and patients with lung cancer to choose a suitable surgical procedure. There is not enough high-quality evidence of RCTs to be included, due to the characteristics of interventions. We will try to include some non-randomized controlled trials, small sample trails. Although our team has experience in carrying out a systematic review and meta-analysis, there may be high heterogeneity and low reliability of evidence, which is the limitation of this study.
Generation of highly efficient terahertz radiation in ferromagnetic heterostructures and its application in spintronic terahertz emission microscopy (STEM)

The laser terahertz emission microscopy (LTEM) technique, which breaks through the resolution limitation of terahertz waves from millimeter to micrometer scales, has been widely used in many real application circumstances, such as contactless chip nondestructive testing, biosensing, imaging, and so on. Recently developed spintronic terahertz emitters featuring many unique properties such as high efficiency, easy integration, low cost, large size and so on, may also have great applications in LTEM, which can be called spintronic terahertz emission microscopy (STEM). To achieve high efficiency and good performance in STEM, we propose and corroborate a remnant magnetization method to radiate continuous and stable terahertz pulses in W/CoFeB/Pt magnetic nanofilms without carrying magnets on the transmitters driven by nJ femtosecond laser pulses. We systematically optimize the incidence angle of the pumping laser and find the emission efficiency is enhanced under oblique incidence, and we finally obtain comparable radiation efficiency and broadband spectrum in W/CoFeB/Pt heterostructures compared with that from 1 mm thick ZnTe nonlinear crystals via optical rectification under the same pumping conditions of 100 fs pulse duration from a Ti:sapphire laser oscillator, which was not previously demonstrated under such long pulse duration. We believe our observations not only benefit for a deep insight into the physics of femtosecond spin dynamics, but also help develop novel and cost-effective broadband spintronic terahertz emitters for the applications in STEM.
ONOFIC‐based leakage reduction technique for FinFET domino circuits

A new technique ON/OFf logIC (ONOFIC) is proposed in this paper for designing domino logic circuits in fin‐field effect transistor (FinFET) deep submicron technology. In this technique, a block named ONOFIC is inserted between pull‐up network (PUN) and pull‐down network (PDN) of domino circuits. The proposed technique is simulated in FinFET short gate (SG) and low power (LP) mode. The subthreshold current which plays a major role to determinate leakage power is very low in this technique. Two‐, 4‐, 8‐, and 16‐input OR gates are simulated with 32‐nm node FinFET technology. In FinFET LP mode, the subthreshold leakage power of the proposed technique is reduced by 15% to 24.3% at 25°C and reduced by 8.71% to 23.4% at 110°C compared with standard domino circuits. The subthreshold leakage power of the proposed circuit is reduced by 19.2% to 57.3% at 25°C and reduced by 17.6% to 60.7% at 110°C compared with leakage control transistor (LECTOR)‐based circuits. In FinFET SG mode, the subthreshold leakage power of the proposed technique is reduced by 7.69% to 17.7% at 25°C and reduced by 0 to 7.85% at 110°C compared with standard domino circuits. The subthreshold leakage power of the proposed circuit is reduced by 60.4% to 73.9% at 25°C and reduced by 45.1% to 65.5% at 110°C compared with LECTOR‐based circuits. The proposed technique is also efficient to reduce subthreshold leakage power in deep nanometer technology nodes from 7 to 20 nm.
Spiking neural network classification for spike train analysis of physiotherapy movements

Classifying gesture or movements nowadays become a demanding business as the technologies of sensor rose. This has enchanted many researchers to actively investigated widely within the area of computer vision. Rehabilitation exercises is one of the most popular gestures or movements that being worked by the researchers nowadays. Rehab session usually involves experts that monitored the patients but lacking the experts itself made the session become longer and unproductive. This works adopted a dataset from UI-PRMD that assembled from 10 rehabilitation movements. The data has been encoded into spike trains for spike patterns analysis. Next, we tend to train the spike trains into Spiking Neural Networks and resulting into a promising result. However, in future, this method will be tested with other data to validate the performance, also to enhance the success rate of the accuracy.
Cholesterol content and fatty acid profile of chocolates mostly consumed in Turkey Contenido de colesterol y perfil de ácidos grasos de los chocolates más consumidos en Turquía

Cholesterol content and fatty acid profile of chocolates that are consumed in Turkey were determined by capillary gas chromatography. Chocolate samples from 20 trade marks were purchased from markets in İzmir, Turkey. As results of the analyses, average cholesterol content of the samples was 1.14 ± 0.14 mg/kg ranging between 0.963 and 1.535 mg/kg. Twenty-three types of fatty acids were determined in oil extracted from chocolates. Main fatty acids found in chocolate samples were stearic acid (39.33 ± 5.25%), oleic acid (25.99 ± 6.89%), and palmitic acid (25.56 ± 2.06%). Total saturated and total unsaturated fatty acid contents of chocolate samples were found as 69.90% and 30.05%, respectively. The fat content of the samples were in the range 31.5–67%.
Layered approach for improving the quality of free-viewpoint depth-image-based rendering images

Abstract. In free-viewpoint rendering systems, one of the most challenging goals is the creation of virtual views based on available color texture (RGB) and depth data. Conventional depth-image-based rendering (DIBR) approaches have assumed that the virtual camera can only be displaced horizontally, thus leading to fairly simple disocclusion artifacts. However, in free-viewpoint DIBR, the virtual camera can be positioned in an arbitrary way and the respective disocclusion artifacts can exhibit complicated anisotropic appearances. Consequently, conventional approaches for compensating disocclusion holes usually fail in such arbitrary camera motion. We present a disocclusion compensation technique based on texture inpainting. We propose a layered representation of both the color and depth images in local foreground, background, and undefined segments (a trimap). This representation allows for employing an efficient alpha-matting approach for reconstructing the underlying opacity layer followed by a background compensation and layered rendering. The performance of the proposed method is evaluated with respect to the state-of-the-art through objective and subjective tests. The achieved results, especially for large camera displacements, outperform the state-of-the-art. Those results assess the effectiveness of the proposed method and highlight the need for new quality metrics able to address the impairments of this type of content.
Upsurging Paratyphoid Fever: A Study from Southern India

Objectives: Enteric fever is still a major public health problem in an endemic country like India. Studies project that Salmonella Typhi is the most common cause in the pediatric population but with a recent rising trend in the number of cases due to Salmonella Paratyphi A with increased morbidity and mortality. Methods: A retrospective analysis of children who had been infected with laboratory-conﬁrmed Salmonella serotypes of Typhi or Paratyphi A collected from November 2016 to October 2018, isolates underwent serotype conﬁrmation, antimicrobial susceptibility testing. Results: A total of 29 isolates of Salmonella species were studied, which revealed an emergence of Salmonella Paratyphi A as predominant serotype accounting for 55.2% (16) cases with remaining 44.8% (13) cases being Salmonella Typhi. Conclusions: Physicians should be aware of the increasing incidence of infection due to Salmonella Paratyphi A and treatment options given its widespread antimicrobial resistance. A paratyphoid fever vaccine is urgently needed. Continued surveillance for paratyphoid fever will help guide future prevention and treatment recommendations. J Microbiol Infect Dis 2020; 10(1):18-23.
Performance of Screening Ultrasonography as an Adjunct to Screening Mammography in Women Across the Spectrum of Breast Cancer Risk.

Importance Whole-breast ultrasonography has been advocated to supplement screening mammography to improve outcomes in women with dense breasts. Objective To determine the performance of screening mammography plus screening ultrasonography compared with screening mammography alone in community practice. Design, Setting, and Participants Observational cohort study. Two Breast Cancer Surveillance Consortium registries provided prospectively collected data on screening mammography with vs without same-day breast ultrasonography from January 1, 2000, to December 31, 2013. The dates of analysis were March 2014 to December 2018. A total of 6081 screening mammography plus same-day screening ultrasonography examinations in 3386 women were propensity score matched 1:5 to 30 062 screening mammograms without screening ultrasonography in 15 176 women from a sample of 113 293 mammograms. Exclusion criteria included a personal history of breast cancer and self-reported breast symptoms. Exposures Screening mammography with vs without screening ultrasonography. Main Outcomes and Measures Cancer detection rate and rates of interval cancer, false-positive biopsy recommendation, short-interval follow-up, and positive predictive value of biopsy recommendation were estimated and compared using log binomial regression. Results Screening mammography with vs without ultrasonography examinations was performed more often in women with dense breasts (74.3% [n = 4317 of 5810] vs 35.9% [n = 39 928 of 111 306] in the overall sample), in women who were younger than 50 years (49.7% [n = 3022 of 6081] vs 31.7% [n = 16 897 of 112 462]), and in women with a family history of breast cancer (42.9% [n = 2595 of 6055] vs 15.0% [n = 16 897 of 112 462]). While 21.4% (n = 1154 of 5392) of screening ultrasonography examinations were performed in women with high or very high (≥2.50%) Breast Cancer Surveillance Consortium 5-year risk scores, 53.6% (n = 2889 of 5392) had low or average (<1.67%) risk. Comparing mammography plus ultrasonography with mammography alone, the cancer detection rate was similar at 5.4 vs 5.5 per 1000 screens (adjusted relative risk [RR], 1.14; 95% CI, 0.76-1.68), as were interval cancer rates at 1.5 vs 1.9 per 1000 screens (RR, 0.67; 95% CI, 0.33-1.37). The false-positive biopsy rates were significantly higher at 52.0 vs 22.2 per 1000 screens (RR, 2.23; 95% CI, 1.93-2.58), as was short-interval follow-up at 3.9% vs 1.1% (RR, 3.10; 95% CI, 2.60-3.70). The positive predictive value of biopsy recommendation was significantly lower at 9.5% vs 21.4% (RR, 0.50; 95% CI, 0.35-0.71). Conclusions and Relevance In a relatively young population of women at low, intermediate, and high breast cancer risk, these results suggest that the benefits of supplemental ultrasonography screening may not outweigh associated harms.
Seroprevalence of Asymptomatic Leishmania spp. Carriage Among Blood Donors in Leishmaniasis Endemic Area in Turkey

Introduction: Transfusion-related infections are usually caused by a microbial pathogen transmitted to the recipient by the donated blood. Plasmodium spp. , Trypanosoma cruzi, Babesia microti, Toxoplasma gondii and Leishmania spp. are listed as the most widely reported transfusion-transmitted parasites. Leishmaniasis is well known as an endemic in Mediterranean countries including Turkey. Accordingly, detection of asymptomatic Leishmania infantum carriage in blood donors is an important issue in Turkey. In endemic teretories, research on blood donors is under-represented in Turkey. Likewise, Mersin province is also endemic for Leishmaniasis. Up to date, no studies have been conducted to detect Leishmaniasis in healthy blood donors in our region. Therefore, the main objective of the current study was to reveal the seroprevalance of asymptomatic Leishmania carriage among the blood donors in Mersin province. Materials and Methods: A total of 509 blood samples were collected from blood donors during a 12-month period between June 2016 and June 2017 at Mersin University Health Research and Application Center. Collected questionnaires were evaluated to determine the risk of exposure to Leishmania spp. Serological and molecular methods were assesed on the collected blood specimens. Results: Based on the questionnaires, a total number of 509 donors participated the study, living in the city center (n= 367), district (n= 121), town (n= 7) and village (n= 14) respectively. A veterinarian and a sailor as well as 17 farmers were listed in the risky occupational groups. The number of dog and cat owner donors were reported as 41 and 20, respectively. All samples were found to be negative for Leishmania spp. by ELISA and real-time polymerase chain reaction methods. Conclusion: This research is the first to assess Leishmaniasis risk in Mersin province. It is highly recommended not to utilize Leishmania spp. screening into the routine test packages in blood banks in our region.
Benefits and lessons learned of implementing building virtual design and construction (VDC) technologies for coordination of mechanical, electrical, and plumbing (MEP) systems on a large healthcare project

SUMMARY: Coordination of Mechanical, Electrical and Plumbing (MEP) systems is a huge challenge for many technical projects such as Healthcare projects, Bio-tech projects and projects in the area of Advanced Technology. The use of Building Information Modeling (BIM) or Virtual Design and Construction (VDC) tools and processes promises to address the challenges of the MEP coordination process. This case study presents the use of BIM / VDC tools and processes for the coordination of MEP systems on a $96.9M healthcare project in Northern California, USA. We discuss the challenges project team members faced in implementing the BIM / VDC tools and processes for MEP coordination, the specific quantitative and qualitative benefits from the use of BIM / VDC tools and processes that each project team member recognized and the lessons that the project team learned by implementing BIM / VDC tools and processes for the coordination of MEP systems. Some of the challenges we discuss include the creation and organization of the MEP coordination process using BIM / VDC tools, creation of the guidelines for the most efficient use of BIM / VDC tools for the process of conflict identification and resolution between the MEP subcontractors, and aligning the contractual interests of the coordination team to meet the overall project schedule. Some of the benefits that the project team achieved by using the BIM / VDC tools and processes for the coordination of the MEP systems include labor savings ranging from 20 to 30 % for all the MEP subcontractors, 100% pre-fabrication for the plumbing contractor, only one recorded injury throughout the installation of MEP systems over a 250,000 square feet project area, less than 0.2% rework for the whole project for the mechanical subcontractor, zero conflicts in the field installation of the systems and only a handful of requests for information for the coordination of the MEP systems between contractors and the designers, and 6 months’ savings on the schedule and about $9M savings in cost for the overall project. The lessons the team learned include the level and type of details team members need to include to achieve benefits from the use of BIM / VDC tools for the coordination of MEP systems.
How Critical is Preschool Attendance for Students to Build a Higher Science Self-efficacy? A Comparative Study of Finland, Singapore, and Turkey Using PISA 2015 Data

Preschool attendance rates have been increasing in recent decades yet there is some level of deviation throughout the participating countries in PISA. Finland and Singapore are the countries with a very high level of preschool attendance rates while the attendance rate in Turkey lags evidently behind the OECD average. In this study, we investigate the association between preschool attendance and science self-efficacy for these countries using the PISA 2015 data. PISA is an international survey study on 15-year-old students’ science, mathematics and reading literacies to evaluate the education systems in the participating countries. Regression analyses for each country have revealed that students’ preschool attendance is associated with their science self-efficacy scores to some degree in all three countries. The difference in self-efficacy seems to be getting larger as the preschool attendance increases. Singapore has the highest effect size while Turkey has the lowest one considering the magnitude of the association.
Büyük Ruminantia’da Fibula’nın Morfolojisi

Bu calisma buyuk ruminantia’da fibula’nin morfolojik yapisinin detayli olarak incelenmesi amaciyla yapildi. Calismada toplamda 24 adet ossa cruris kullanildi. Kemiklerin morfometrik olcumlerini elde etmek icin Mitutoya Dijital Kumpas’tan (Mitutoyo, Japan) yararlanildi. Elde edilen bulgular sonucunda buyuk ruminantia’lar da fibula boyu hayvanlar arasinda degisiklik gostermekteydi. Bu durum’un ozellikle hekimler tarafindan tibia travmalarinda goz onunde bulundurulmasi gerektigi ve bu alanda calisacak arastirmacilara yardimci olacagi dusunulmektedir.
The role of NUDT21 in microRNA‐binging sites of EZH2 gene increases the of risk preeclampsia

Preeclampsia (PE) is a major cause of mortality and morbidity among pregnant mothers and their fetuses worldwide. Recent studies have shown that several microRNAs (miRNAs) play crucial role in pathogenesis of PE patients; however, the mechanisms responsible for differences in miRNA function in PE largely remain to be determined.