Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification and Quantification of Dopamine Receptor 2 in Human Eutopic and Ectopic Endometrium : A Novel Molecular Target for Endometriosis Therapy 1

Previous studies in an experimental mouse model of endometriosis have shown that the dopamine agonist (DA) cabergoline (Cb2) reduces angiogenesis and endometriotic lesions, hypothetically binding to the dopamine receptor type-2 (DRD2). To date, this has not been described in human endometrium and/or endometriotic lesions. Thus, we aimed to investigate the presence of DRD2 in said tissues. Endometrium fragments were implanted in nude mice treated with different doses of Cb2. Polymerase chain reaction assays and immunohistochemistry were performed to analyze the gene and protein expressions (respectively) of DRD2, VEGF, and VEGF receptor-2 (KDR). In addition, lesions and endometrium from women with mild and severe endometriosis and endometrium from healthy women were collected to analyze their gene expression profile. In experimental endometriosis, DRD2 was expressed at gene and protein levels in all three groups. VEGF gene and protein expressions were significantly lower in lesions treated with Cb2 than in controls. KDR protein expression was significantly lower in experimental lesions treated with Cb2 than in controls. In eutopic endometria, there was a significant decrease in DRD2 expression and an increase in VEGF in women with mild and severe endometriosis with respect to healthy patients. In endometriosis, KDR expression was significantly higher in red than in white and black lesions. VEGF expression was significantly lower in black than in red lesions. DRD2 is present in the human eutopic and ectopic endometrium and is regulated by DA, which provides the rationale for pilot studies to explore its use in the treatment of endometriosis. angiogenesis, cabergoline, dopamine, dopamine agonist, dopamine receptor 2, endometriosis, endometrium, KDR, VEGF
Effects of Environmental Oil Spills on Commercial Fish and Shellfish in Suez Canal and Suez Gulf Regions ( Review Article )

Oil pollution is a major environmental problem and is important, in particular to the Suez Canal and Suez Gulf as the main routes of many oil tankers. In view of the increased incidents of oil spills, it was necessary to discuss the impact of oil spills on the fishery community. In this review, the following approaches will be attributed: a) the morphological, biochemical and pathological reactions of marine fish and shellfish to oil pollution. b) The impact of oil toxicity in spawning and reproduction of shellfish and migratory fish. c)the bacterial solving crude oil. d) The expected effects of that pollution on human health. This project includes: analysis of water quality (chemical, physical, etc), detection of oil pollutants residues in water, fish and shellfish, and parasitic diseases affecting fish, studying of the pathological and clinico-pathological affections of such fishes, and the impact of oil pollution on fish resources and trials of prevention and control of such pollution. [Mona S. Zaki; Mohammad M. N. Authman; Nagwa S. Ata; Mostafa F. Abdelzaher and Abdel Mohsen M. Hammam. Effects of Environmental Oil Spills on Commercial Fish and Shellfish in Suez Canal and Suez Gulf Regions (Review Article). Life Sci J 2014;11(2):269-274]. (ISSN:1097-8135). http://www.lifesciencesite. com. 36
A FEATURE CLUSTERING BASED DIMENSIONALITY REDUCTION FOR INTRUSION DETECTION ( FCBDR )

This work discusses the approach for intrusion detection and classification by devising a membership function, inspired from Yung, Jung, & Shie-Jue (2014) and used in this work to carry the dimensionality reduction of processes present in the training set in evolutionary approach. The reduced process representation may then be used to perform classification and prediction for detecting intrusion. It is seen that the reduced representation of processes retains the system call distribution of the initial process. Experiment results show the proposed approach is better compared to existing approaches and helps in effective identification of U2R and R2L attacks.
Vasculogenic Mimicry and Its Role in Cancer

It has been found that, on inhibition of angiogenesis, many tumors develop alternative strategies for self-supply with nutrients. One of these strategies is Vasculogenic Mimicry. Vasculogenic Mimicry (VM) is de novo formation of perfusable, matrix-rich, vasculogenic-like networks by aggressive tumour cells. The initial morphologic and molecular characterization of VM was made in human melanoma in which the tumour cells were shown to co-express endothelial and tumour markers and formed channels, networks, and tubular structures that are rich in laminin, collagens IV and VI, and heparin sulphate proteoglycans, containing plasma and red blood cells, indicating a perfusion pathway for rapidly growing tumors, as well as an escape route for metastasis. Vascular mimicry was originally located in melanoma. It has since been observed in many tumors including hepatocellular carcinoma, gastric adenocarcinoma, gall bladder carcinoma, ovarian cancer and prostate cancer. This review embodies the mechanism of VM, discovered so far, along with its effect on various tumors.
Examining the Relationship between Transformational Leadership and Employee Empowerment

Transformational leadership is a leadership style that has been used to increase the followers’ performance and it has been proven by many studies as effective leadership in increasing organizational effectiveness. One of the significant outcomes of transformational leadership is the employee empowerment. The employee empowerment shows that the employees have authorities over their jobs as well as enhancing their in decision making. The empowerment of employee is one of the ways for a company to increase it’s efficiency. This is because the empowered employees are able to find opportunities and solve problems by their own. This paper presents the study on the relationship between transformational leadership and the employee empowerment. A cross-sectional survey is has been done with the total of 113 employees from the selected banks in Kuala Terengganu. The correlation analysis was used to determine the relationship between transformational leadership and the employee empowerment. The result indicates a significant relationship between transformational leadership and employee empowerment
Nasal Carriage Prevalence of MRSA in People Living with HIV / AIDS Undertaking Antiretroviral Therapy in a Tertiary Hospital in Port Harcourt

Methicillin resistant Staphylococcus aureus (MRSA) is a bacterium which is known globally to cause several difficult to treat infections in humans both in the hospital and community settings. It is also referred to as Oxacillin Resistant Staphylococcus aureus (ORSA). Staphylococci are members of the family Micrococcaceae. They are Gram-positive, non motile spherical bacteria, catalase-positive, do not form spores, facultatively anaerobic and occur singly and in irregular grapelike clusters. This study was aimed at determining the prevalence of MRSA nasal colonization of HIV positive patients in a Tertiary Hospital in Rivers State. A total of 217 study participants were recruited. From each participant, specimen for Staphylococcus aureus culture was collected from the anterior nares, using sterile swabs moistened with distilled water. Moistened sterile swab sticks were inserted into the nostrils 1-2 cm inside, swabbing it in clockwise direction for 3-4 times. The swabs were immediately transported to the Medical Microbiology and Parasitology Laboratory of the University of Port Harcourt Teaching Hospital for culture on Mannitol salt agar . Biochemical tests and antimicrobial testing was carried out on isolates. Blood samples were also collected from the participants from their median cubital vein using a sterile ethylene diamine tetra acetic acid vacutainer needle and tube. The blood samples were sent to the HIV Research Laboratory, where CD4 cell counts were done using a flow cytometer. However, nasal screening in this study identified 82(37.79%) S. aureus carriers. Out of these, 82(37.79%) Staphylococcus aureus isolates, 54(24.88%) isolates were Methicillin Resistant based on Oxacillin (1μg) disc and 35 isolates were methicillin resistant based on cefoxitin (30μg) disc giving a prevalence of 16.13% in the studied population. Conclusively, it is critical to note that, Staphylococcus aureus that are MRSA continue to evolve as an important agent of infection in HIV positive subjects attending the University of Port Harcourt Teaching Hospital. This study also established that there was an equal likelihood of isolation of MRSA from people living with HIV/AIDS irrespective of their CD4+ count or the stage of their disease progression.
TYPICAL AND ATYPICAL PROPERTIES OF PERIODIC TEICHMÜLLER GEODESICS

Consider a component Q of a stratum in the moduli space of area one abelian differentials on a surface of genus g. Call a property P for periodic orbits of the Teichmüller flow on Q typical if the growth rate of orbits with property P is maximal. Typical are: The logarithms of the eigenvalues of the symplectic matrix defined by the orbit are arbitrarily close to the Lyapunov exponents of Q, and its trace field is a totally real splitting field of degree g over Q. If g ≥ 3 then periodic orbits whose SL(2,R)-orbit closure equals Q are typical. We also show that Q contains only finitely many algebraically primitive Teichmüller curves, and only finitely many affine invariant submanifolds of rank l ≥ 2.
Fault injection technology in Testability Verification experiment

Fault injection is the key technology in equipment testability verification. With the degree of development of modern equipment, the testability needs to further improve the level, fault injection technology needs further development. Comparative analysis of the common fault injection method, different fault injection methods are classified, the fault injection technique proposed future development prospects, provide technical support and equipment for the verification test work.
Pisces , Cyprinidae ) conservation aquaculture : first 1 attempt at artificial reproduction and larval rearing 2

Brook chub, Squalius lucumonis (Pisces, Cyprinidae) conservation aquaculture: first 1 attempt at artificial reproduction and larval rearing 2 Lorenzo Tancioni, Marco Martinoli, Paola Olivo, Arnold Rakaj, Federica De Lutiis, 3 Arianna Martini, Clara Boglione* 4 a Experimental Ecology and Aquaculture Laboratory, Biology Department,‘‘Tor Vergata’’ 5 University of Rome, Rome, Italy 6 b Department of Biology, Evolutionary Developmental Biology, Gent University, Gent, 7 Belgium 8 * Corresponding author 9 ABSTRACT 10 Many recovery programs for endangered species rely on the release of hatchery-reared 11 juveniles to support threatened populations or to re-build new ones. In the framework of a 12 conservation plan for the Italian critically endangered fish (sensu IUCN Red List) Squalius 13 lucumonis, artificial reproduction and larval rearing was carried out for the first time. Wild 14 breeders were collected during reproductive period (May-June) by electrofishing from 15 Fosso Corese, a small tributary of Tiber River (Central Italy). In situ stripping of gametes 16 followed by manual fecundation was carried out. Ex situ incubation of eggs and larval 17 rearing were conducted in the hatchery of LESA (University of Tor Vergata). With the aim of 18 producing fingerlings with “wild-like” behavior, a larval rearing technique in a “green water” 19 large volume tank was applied. For the first time, about 400 fingerlings (87 days old) of 20 brook chub were obtained from about 2,300 free embryos (17% survival rate). This result is 21 promising as it demonstrates the technical feasibility of brook chub conservation 22 aquaculture, the first step for an in situ-ex situ recovery plan for this species based on 23 reared fingerlings’ restocking. 24
Planetary Rover Localization Design : Antecedents and Directions

This paper describes the localization problem in planetary rovers and its influence in the mission success. This manuscript gives an overview of the localization subsystem from a system level perspective and its impact on mission operations. It discusses current problems on the design of proper sensor fusion scheme and addresses future challenges which needs to be pursued in order to move forward planetary rovers into more intelligent vehicles for future planetary missions.
Relationship Between a CEO’s Level of Education and Corporate Social Responsibility: Evidence from Chinese Listed Firms

This study investigates the influence of a CEO’s level of education on the Corporate Social Responsibility (CSR) of listed firms in China. We find a significant and positive impact of the CEO’s level of education on the CSR of a firm, one level promotion of CEOs' education will increase 0.1630 CSR scores of a firm and increase the probability of CSR disclosure by 10.75%. This finding is robust for the univariable analysis and for sub-items and the forward performance of CSR. Further, we find that the positive relationship between the CEO’s level of education and CSR is more pronounced for CEOs who also chair the board, state-owned firms and CEOs who have overseas experience. More concretely, when the CEO is also the chairman, the CEO’s level of education has a greater positive effect on CSR than those are not chairman. In state-owned enterprises, the CEO’s level of education plays a greater role in the positive promotion of the CSR than non-stated-owned enterprises. When the CEO has studied or worked abroad, the CEO’s level of education has a greater positive effect on the CSR than those who do not have overseas experience. Our findings shed light on the role of the CEO’s level of education in CSR, and our research on Chinese listed companies enriches the relevant research on CSR in developing countries.
eural signatures of social conformity : A coordinate-based activation ikelihood estimation meta-analysis of functional brain imaging tudies

People often align their behaviors with group opinions, known as social conformity. Many neuroscience studies have explored the neuropsychological mechanisms underlying social conformity. Here we employed a coordinate-based meta-analysis on neuroimaging studies of social conformity with the purpose to reveal the convergence of the underlying neural architecture. We identified a convergence of reported activation foci in regions associated with normative decision-making, including ventral striatum (VS), dorsal posterior medial frontal cortex (dorsal pMFC), and anterior insula (AI). Specifically, consistent deactivation of VS and activation of dorsal pMFC and AI are identified when people’s responses deviate from group opinions. In addition, the deviation-related responses in dorsal pMFC predict peoctivation likelihood estimation
AVISO Sea Surface Height above Geoid

1. Intent of This Document and Point of Contact (POC) 1a) This document is intended for users who wish to compare satellite derived observations with climate model output in the context of the CMIP5/IPCC historical experiments. Users are not expected to be experts in satellite derived Earth system observational data. This document summarizes essential information needed for comparing this dataset to climate model output. References are provided at the end of this document to additional information for the expert user.
Environmental and genetic factors in age-related hearing impairment Aging Clinical and Experimental Research

Age-related hearing impairment (ARHI), or presbycusis, is a complex disease with multifactorial etiology. It is the most prevalent sensory impairment in the elderly, and may have detrimental effects on their quality of life and psychological well-being. The aim of this paper is to give an overview of the current data on ARHI, focusing mainly on environmental agents and genetic predisposition in animal models and in humans. With improvement of our understanding of ARHI, treatment other than with amplification will be hopefully possible in the long term. (Aging Clin Exp Res 2011; 23: 3-10) ©2011, Editrice Kurtis Several genes encoding proteins specific to the ear have been identified, and genotypic differences found in tissue samples from both humans and animals can be observed by means of powerful molecular techniques. The aim of this paper is to give an overview of current data relating to ARHI, focusing mainly on environmental agents and genetic predisposition in animal models and in humans. Various techniques of prevention and future therapeutic strategies are also discussed. ENVIRONMENTAL FACTORS Several environmental agents and medical conditions may accelerate age-dependent hearing loss, although with different degrees of importance and experimental evidence.
IMPORTANCE OF MAINTAINING DEFECT CORES

Pruning increases value by encouraging clearwood growth. If pruning is delayed the defect core (DC) expands and clearwood conversion reduces. The objective of this study was to examine defect cores within Pinus radiata D. Don stems to determine how well they had been maintained through multiple pruning lifts. Analysis of 4526 currently standing trees suggests that one-fifth of future crop may have defect cores extending 4 cm or more beyond that initially targeted. Furthermore, results indicate that each 1 cm increase in defect core causes an estimated conversion loss of 2.5%, equivalent to a loss in value of $10/m3 sawn (exmill). For a direct regime on fertile sites, the cost of the expanded defect core is estimated at $880/ha. Bucking may offer the possibility of recovering some lost value. The importance and magnitude of defect cores are further emphasised through identification of threshold levels of small-end diameter required to obtain clearwood conversions at a given level. This provides a foundation upon which new log grades can be developed.
Housing needs of Polish seniors

The growing share of seniors in the population of Poland and the lack of systemic solutions in the field of social security, resulting from the lack of diagnosis of real needs of this group, imposes the extension of research tasks undertaken so far. Such diagnosis is needed to build a housing system for the Polish seniors. The objective of the article is to present selected results of research on the needs of people aged 60+ conducted in 2017. The study of quantitative and qualitative nature, was based an online questionnaire (CAWI — Computer-Assisted Web Interview) as well as on a questionnaire distributed in paper form and individual interviews were also conducted (IDI — In-depth Interview). The results of the quantitative research together with the recommendations included in the expertise can constitute a field for entrepreneurship at various levels of activities in construction and services related to facilities in the existing housing infrastructure. Senior housing requires sectoral cooperation, various forms of construction and financing models for housing construction.
Analytical Review of Data Transformation for the Task of Integrating Various Representations on the Example of Ontologies and Relational Databases

This article provides an overview of the data transformation solutions needed to integrate various models and data schemas. An example of mutual mapping of ontologies on relational databases is considered. The scientific basis of the presented data models is described. Also set goals and objectives for data integration. The article describes the problems and further steps to explore the possibility of data transformation in computer-aided design systems. The main problem of transforming a relational database into an ontology is the lack of metadata. With the inverse transform, some data and metadata may be lost. In addition, there are several approaches to the transformation of ontologies into relational databases. OWL is used as the ontology description language. The article is useful to architects and software designers, as well as knowledge engineering specialists.
DAMAGE OF 3 D TUNGSTEN TARGETS IN THE COURSE OF ITER ELM-LIKE HEAT LOADS

The damage of tungsten target under repetitive plasma loads have been studied with a quasi-stationary plasma accelerator QSPA Kh-50. The target construction was close to the ITER divertor reference design. The plasma stream parameters were relevant to ITER ELMs (surface heat load of 0.9 MJ/m 2 and pulse duration of 0.25 ms). The features of surface erosion and particle emission have been investigated in the course of increasing number of plasma pulses. The number of solid/droplet particles separated from the exposed target and their dynamics depend on the applied exposition dose. The contribution of different erosion mechanisms to the tungsten target destruction was evaluated. PACS: 52.40. HF
An Integrated Discrete-Time Delay-Compensating Technique for Large-Array Beamformers

This paper implements a wide aperture high-resolution true time delay for frequency-uniform beamforming gain in large-scale phased arrays. We propose a baseband discrete-time delay-compensating technique to augment the conventional phase-shift-based analog or hybrid beamformers. A generalized design methodology is first developed to compare delay-compensating analog or hybrid beamforming architecture with their digital counterpart for a given number of antenna elements, modulation bandwidth, ADC dynamic range, and delay resolution. This paper shows that delay-compensating analog or hybrid beamformers are more energy-efficient for high dynamic-range applications compared to true-time-delay digital beamformers. To demonstrate the feasibility of our proposed technique, a four-element analog delay-compensating baseband beamformer in 65-nm CMOS is prototyped. A time-interleaved switched-capacitor array implements the discrete-time delay-compensating beamformer with a wide delay range of 15-ns and 5-ps resolution. Measured power consumption is 47 mW with frequency-uniform array gain over 100-MHz modulated bandwidth, independent of angle of arrival. The proposed delay compensation scheme is scalable to accommodate the delay differences for large antenna arrays with higher range/resolution ENOB compared with prior art.
PRACTICAL IMPLEMENTATION OF THE NEUROMORPHIC TRENABLE CIRCUIT FOR DEVICE MISMATCH

Random device mate that arises as a result of scaling of the CMOS (complementary metal-oxide semiconductor) technology into the deep sub micrometer regime degrades the accuracy of analogy circuits. Ways to combat this increase the quality of style. We’ve got developed a unique a neuromorphic system called a trainable analogy block (TAB), which exploits device mate as a method for random projections of the input to a better dimensional house. The TAB framework is inspired by the principles of neural population secret writing operational in the biological system. 3 neural layers, namely input, hidden, and output, represent the TAB framework, with the number of hidden layer neurons so much surpassing the input layer neurons. Here, we have a tendency to gift measure results of the primary epitome TAB chip designed employing a sixty-five nm method technology and show its learning capability for numerous regression tasks. Our TAB chip is tolerant to inherent randomness and variability arising thanks to the fabrication method. to boot, we have a tendency to characterize every vegetative cell and discuss the applied mathematics variability of its standardization curve that arises due to random device mate, a fascinating property for the learning capability of the TAB. we have a tendency to conjointly discuss the impact of the number of hidden neurons and therefore the resolution of output weights on the accuracy of the training capability of the TAB. we have a tendency to show that the TAB could be a low power system—the power dissipation within the TAB with 456 vegetative cell blocks is one.38 we.