Miracle-dz/UniFAR-FTUs huggingface dataset:
Low-Frequency Input Current Ripple Reduction Based on Load Current Feedforward in a Two-Stage Single-Phase Inverter

A large amount of ripple at twice the output frequency will emerge in the input current due to the pulsating output power in a two-stage single-phase inverter. To reduce the low-frequency input current ripple, a control strategy is presented in this paper based on the front-end dc-dc converter load current feedforward. It intends to control the dc bus voltage to swing properly at twice the output frequency, making the dc bus capacitor supply nearly all the pulsating power. The implementation method is illustrated, and the operation performance analysis as well as the key parameter design principle is provided. Introducing the proposed feedforward path is able to significantly suppress the input current ripple with little impacts on the original system stability, steady-state tracking accuracy, and dynamic response. Finally, experimental results performed on a buck-type stand-alone two-stage single-phase inverter prototype verify the validity of proposed method and the correctness of analysis.
Vitis Vinifera ( Grape ) Ingredients as Used in Cosmetics February 17 , 2012

All interested persons are provided 60 days from the above date to comment on this Scientific Literature Review and to identify additional published data that should be included or provide unpublished data which can be made public and included. Information may be submitted without identifying the source or the trade name of the cosmetic product containing the ingredient. All unpublished data submitted to CIR will be discussed in open meetings, will be available at the CIR office for review by any interested party and may be cited in a peerreviewed scientific journal. Please submit data, comments, or requests to the CIR Director, Dr. F. Alan Andersen.
Prophylaxis for severe haemophilia: clinical and economical issues

Summary. Patients with severe haemophilia are treated either in case of bleeds only (on demand), or with regular infusions of clotting factor to prevent bleeds (prophylaxis). The introduction of prophylaxis has been hampered by issues of cost and viral safety. In order to compare results and treatment cost of different treatment strategies in adults, three cohorts of patients with severe haemophilia (born 1970–1980) were compared.
Safety and efficacy of trivalent inactivated influenza vaccine in young children: a summary for the new era of routine vaccination

Increasing use of influenza vaccine in children is expected as this important virus becomes more widely recognized as a major cause of morbidity in young children. Clinicians and third party payers must consider the implications of national vaccine use recommendations, with their current focus on young children, on their practices and on the community at large. Two influenza vaccines are available in the United States, an inactivated, trivalent intramuscular formulation (TIV) which is approved for use among children ≥6 months of age; and a live, attenuated intranasal trivalent preparation (LAIV) indicated for healthy persons 5 to 49 years of age. This review summarizes available data regarding the safety and efficacy of TIV, in comparison with LAIV, with particular attention to children <9 years of age, the population for whom two doses of vaccine are recommended for first time vaccination. It is apparent that relatively few data are available on the safety of TIV in young children, that important age-specific differences in TIV vaccine efficacy exist and that LAIV appears similar to TIV with regard to safety and efficacy in younger children, but no head-to-head comparison of these two licensed products is available.
The framework for spatiotemporal sequential rule mining: Crime data case study

Sequence pattern and sequential rule mining techniques are used in many application areas. In our research, we look at the possibility of applying these techniques to spatiotemporal data for the use case of crime data mining. For that, we design the framework that coverts data information into spatiotemporal sequences, in order to detect sequential rules. In the paper, we look at the each step of the framework: data normalization, geocoding, building spatiotemporal enumerated entities, building sequences and applying the sequence pattern mining algorithms. We provide the description of the methods that are involved in the framework workflow with their full description jointly with the pseudo code. For the case study, we use publicly available crime data. Based on that data, we design the use case and show how the framework can be used to find patterns and rules among crimes from the spatial and temporal perspectives.
Multifaceted Activities of the HIV-1 Transactivator of Transcription, Tat*

Human immunodeficiency virus, type 1 (HIV-1) is the etiological agent for the acquired immunodeficiency syndrome (AIDS). HIV-1 is a retrovirus that encodes a small nuclear transcriptional activator protein, Tat (Fig. 1). In vivo, Tat is required for virus replication and is conserved in the genomes of all primate lentiviruses (1). Over the past decade, the transcriptional function(s) of Tat (reviewed in detail several years ago (2)) has been intensely investigated. It has become clear that a primary role for Tat is in regulating productive and processive transcription from the HIV-1 long terminal repeat (LTR). Tat also has other activities; some are consistent with that of a secreted growth factor (3–5) and a potentiator of reverse transcription (6). Here we review recent insights into the multifaceted activities of Tat.
Potential of Waste Water Use for Jatropha Cultivation in Arid Environments

Water is crucial for socio-economic development and healthy ecosystems. With the actual population growth and in view of future water scarcity, development calls for improved sectorial allocation of groundwater and surface water for domestic, agricultural and industrial use. Instead of intensifying the pressure on water resources, leading to conflicts among users and excessive pressure on the environment, sewage effluents, after pre-treatment, provide an alternative nutrient-rich water source for agriculture in the vicinity of cities. Water scarcity often occurs in arid and semiarid regions affected by droughts and large climate variability and where the choice of crop to be grown is limited by the environmental factors. Jatropha has been introduced as a potential renewable energy resource since it is claimed to be drought resistant and can be grown on marginal sites. Sewage effluents provide a source for water and nutrients for cultivating jatropha, a combined plant production/effluent treatment system. Nevertheless, use of sewage effluents for irrigation in arid climates carries the risk of salinization. Thus, potential irrigation with sewage effluents needs to consider both the water requirement of the crop and those needed for controlling salinity build-up in the top soil. Using data from a case study in Southern Morocco, irrigation requirements were calculated using CROPWAT 8.0. We present here crop evapotranspiration during the growing period, required irrigation, the resulting nutrient input and the related risk of salinization from the irrigation of jatropha with sewage effluent.
Protease‐activated receptor‐1 drives pancreatic cancer progression and chemoresistance

Protease activated receptor (PAR)‐1 expression in tumor cells is associated with disease progression and overall survival in a variety of cancers of epithelial origin; however, the importance of PAR‐1 in the tumor microenvironment remains unexplored. Utilizing an orthotopic pancreatic cancer model in which tumor cells are PAR‐1 positive whereas stromal cells are PAR‐1 negative, we show that PAR‐1 expression in the microenvironment drives progression and induces chemoresistance of pancreatic cancer. PAR‐1 enhances monocyte recruitment into the tumor microenvironment by regulating monocyte migration and fibroblast dependent chemokine production thereby inducing chemoresistance. Overall, our data identify a novel role of PAR‐1 in the pancreatic tumor microenvironment and suggest that PAR‐1 may be an attractive target to reduce drug resistance in pancreatic cancer.
The MAPK Scaffold Kinase Suppressor of Ras Is Involved in ERK Activation by Stress and Proinflammatory Cytokines and Induction of Arthritis1

The MAPK ERK is required for LPS-induced TNF production by macrophages. Although the scaffold kinase suppressor of Ras (KSR)1 is required for efficient Erk activation by mitogenic stimuli, the role of KSR1 in ERK activation by inflammatory and stress stimuli is unknown. In this study, we examined the effects of KSR deficiency on ERK activation by stress stimuli and show that ERK activation by TNF, IL-1, and sorbitol is attenuated in the absence of KSR1. To determine the significance of this defect in vivo, we tested KSR-deficient mice using a passive transfer model of arthritis. We found that the induction of arthritis is impaired in the absence of KSR. Thus, KSR plays a role in ERK activation during inflammatory and stress responses both in vitro and in vivo.
Market Potential of Cut Flowers Produced in the Marginal Upland Communities in Leyte

Cut flower production can be an alternative livelihood source to farmers who are dependent on subsistence farming. This study aimed to assess the market potential of cut flowers produced in the marginal upland communities in Leyte, specifically Inopacan, which is considered as one of the poorest municipalities in Region 8. This study employed a survey research design where data on the purchasing behavior, consumption, and preferences of the consumers toward buying cut flowers were collected. The respondents were selected using a non-probability sampling technique by means of purposive sampling. Key informant interviews with the florists were also conducted to ascertain the demand and supply situation of cut flowers in the region. Conjoint analysis was used to determine the preferences of the consumers toward buying cut flowers. Results showed that price strongly influenced the consumers in their purchasing decisions. Locally sourced cut flowers are preferred due to its extended longevity. Only around one-fourth of the total local demand can be provided by the local growers, thus production in the marginal uplands in Inopacan, Leyte is seen to have favorable market potential given the climatic condition of the area.
REM sleep behavior disorder predicts cognitive impairment in Parkinson disease without dementia

Objective: To assess the relationship between the presence of REM sleep behavior disorder (RBD) and the cognitive profile of nondemented patients with Parkinson disease (PD). Background: Cognitive impairment is an important nonmotor symptom in PD. Waking EEG slowing in nondemented PD has been related to the presence of RBD, a parasomnia affecting brainstem structures and frequently reported in PD. For this reason, RBD may be associated with cognitive impairment in PD. Methods: Thirty-four patients with PD (18 patients with polysomnographic-confirmed RBD and 16 patients without RBD) and 25 healthy control subjects matched for age and educational level underwent sleep laboratory recordings and a comprehensive neuropsychological assessment. Results: Patients with PD and concomitant RBD showed significantly poorer performance on standardized tests measuring episodic verbal memory, executive functions, as well as visuospatial and visuoperceptual processing compared to both patients with PD without RBD and control subjects. Patients with PD without RBD had no detectable cognitive impairment compared to controls. Conclusions: This study shows that cognitive impairment in nondemented patients with Parkinson disease (PD) is closely related to the presence of REM sleep behavior disorder, a sleep disturbance that was not controlled for in previous studies assessing cognitive deficits in PD. GLOSSARY: BDI-II = Beck-II Depression Inventory; DLB = dementia with Lewy bodies; DSM-IV = Diagnostic and Statistical Manual of Mental Disorders; EOG = electro-oculograms; ICSD = International Classification of Sleep Disorders; MMSE = Mini-Mental State Examination; PD = Parkinson disease; PD-NRBD = patients with PD without RBD; PD-RBD = patients with concomitant RBD; RAVLT = Rey Auditory Verbal Learning Test; RBD = REM sleep behavior disorder; UPDRS = Unified Parkinson's Disease Rating Scale.
An interdisciplinary perspective on information retrieval

Let me begin by saying how honored I am to receive the Gerard Salton Award from SIGIR. His pioneering work, including the vector space model, term weightings, relevance feedback, and the development and evaluation of automatic text retrieval systems, defined and shaped the field in important ways. I did not have many opportunities to interact directly with Gerry Salton, although our paths did cross in interesting ways. Shortly after I started working at Bell Labs, I was introduced to the field of information retrieval by Michael Lesk, who had worked with Gerry at Harvard in the mid-1960s to develop the original SMART system. The last conference at which I interacted with Gerry was not SIGIR or TREC, as one might expect, but rather CHI 1995, where he spoke at panel entitled, Browsing vs. search: Can we find a synergy? ’, a theme to which I return. Following the tradition of previous recipients of the Salton Award (Gerard Salton (1983), Karen Spärck Jones (1988), Cyril Cleverdon (1991), William Cooper (1994), Tefko Saracevic (1997), Stephen Robertson (2000), W. Bruce Croft (2003), and C. J. “Keith” van Rijsbergen (2006)), I present a personal reflection on information retrieval. I begin with some remarks on the problems that have motivated my research in the area for almost three decades, and the approaches that I have taken to address them. I conclude by identifying, what I believe to be, some important opportunities to continue to extend and improve information retrieval moving forward.
Frequency discrimination as a function of frequency and sensation level.

Frequency discrimination was measured for frequencies from 200 to 8000 Hz and for sensation levels from 5 to 80 dB using pulsed sinusoids as stimuli in an adaptive two‐interval force‐choice psychophysical procedure. An analysis of variance indicated significant effects of frequency and sensation level, and of the interaction between frequency and sensation level. The effect of sensation level is greatest at low frequencies and decreases at high frequenices, being quite small at 8000 Hz. The data are used to evaluate the predictions of current theoretical models.
What subcortical–cortical relationships tell us about processing speech in noise

To advance our understanding of the biological basis of speech‐in‐noise perception, we investigated the effects of background noise on both subcortical‐ and cortical‐evoked responses, and the relationships between them, in normal hearing young adults. The addition of background noise modulated subcortical and cortical response morphology. In noise, subcortical responses were later, smaller in amplitude and demonstrated decreased neural precision in encoding the speech sound. Cortical responses were also delayed by noise, yet the amplitudes of the major peaks (N1, P2) were affected differently, with N1 increasing and P2 decreasing. Relationships between neural measures and speech‐in‐noise ability were identified, with earlier subcortical responses, higher subcortical response fidelity and greater cortical N1 response magnitude all relating to better speech‐in‐noise perception. Furthermore, it was only with the addition of background noise that relationships between subcortical and cortical encoding of speech and the behavioral measures of speech in noise emerged. Results illustrate that human brainstem responses and N1 cortical response amplitude reflect coordinated processes with regards to the perception of speech in noise, thereby acting as a functional index of speech‐in‐noise perception.
Website Study: What Information are Prospective Graduate Students Seeking?

The purpose of this website study was to get feedback from recently admitted students to discover if the site was meeting their needs and expectations for information regarding the program and processes. Websites are often the first contact a student has with a university and, especially for those seeking a degree online, could potentially leave students with more questions than answers. After a thorough examination of the current website, an open-ended survey was created and distributed through SurveyMonkey in an attempt to gather information regarding the content and usability of the current site. Because of the responses, changes were made to the content and layout of the website including links to provide easy access to the application, tuition information, and academic calendar. Included in this paper is background information on websites and the department, as well as the purpose, results, list of improvements, and future planned phases. As a result of this study it was anticipated that issues would be brought to light and would lead the department to make effective changes that would improve the experiences of online students that rely on internet based resources for their information. James H. Lampley & Megan E. Owens Website Study: What Information are Prospective Graduate Students Seeking? 56 Journal of Academic Administration in Higher Education 57 Fall 2015 (Volume 11 Issue 2) is filled with inaccurate or disjointed information that is difficult to navigate (Shea, 2005; Shorr, 2014).
Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

In several murine models of autoimmune arthritis, Th17 cells are the dominant initiators of inflammation. In human arthritis the majority of IL-17–secreting cells within the joint express a cytokine phenotype intermediate between Th17 and Th1. Here we show that Th17/1 cells from the joints of children with inflammatory arthritis express high levels of both Th17 and Th1 lineage-specific transcription factors, RORC2 and T-bet. Modeling the generation of Th17/1 in vitro, we show that Th17 cells “convert” to Th17/1 under conditions that mimic the disease site, namely low TGFβ and high IL-12 levels, whereas Th1 cells cannot convert to Th17. Th17/1 cells from the inflamed joint share T-cell receptor (TCR) clonality with Th17 cells, suggesting a shared clonal origin between Th17 and Th17/1 cells in arthritis. Using CD161, a lectin-like receptor that is a marker of human Th17, we show synovial Th17 and Th17/1 cells, and unexpectedly, a large proportion of Th1 cells express CD161. We provide evidence to support a Th17 origin for Th1 cells expressing CD161. In vitro, Th17 cells that convert to a Th1 phenotype maintain CD161 expression. In the joint CD161+ Th1 cells share features with Th17 cells, with shared TCR clonality, expression of RORC2 and CCR6 and response to IL-23, although they are IL-17 negative. We propose that the Th17 phenotype may be unstable and that Th17 cells may convert to Th17/1 and Th1 cells in human arthritis. Therefore therapies targeting the induction of Th17 cells could also attenuate Th17/1 and Th1 effector populations within the inflamed joint.
A peptide from thrombospondin 1 modulates experimental erosive arthritis by regulating connective tissue growth factor.

OBJECTIVE Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with leukocyte adhesion to and extravasation through vascular endothelium into synovial tissue. Recent evidence indicates that the thrombospondin 1 gene is up-regulated in patients with RA. We have identified a region within the TSP-1 type 3 repeats that inhibits human neutrophil elastase (HNE) and binds to human neutrophils. The present study was undertaken to investigate the therapeutic benefit of this TSP-1-derived peptide sequence and its effect on connective tissue growth factor (CTGF), a protein involved in fibrotic disorders and in neovascularization, which is a hallmark of RA. METHODS CTGF gene and protein expression, as well as protein levels of CTGF in the synovium, after treatment with the TSP-1-derived peptide were studied in the peptidoglycan-polysaccharide animal model of erosive arthritis. RESULTS Peptide treatment prevented joint infiltration and inflammation and was associated with reduced circulating antigen levels of HNE and TSP-1. Additionally, CTGF was up-regulated in this experimental model of RA. Treatment with the TSP-1-derived peptide was associated with down-regulation of the message and protein levels of CTGF. Immunofluorescence studies showed that the mean area fraction of CTGF immunoreactivity in the peptide-treated group of animals was significantly less than that in the untreated group. CONCLUSION These results document a role for TSP-1 in regulating CTGF gene and protein expression in synovial tissue, suggesting a link with the disease course in this model of RA. This TSP-1-derived synthetic peptide may represent an important template for drug development in RA and other inflammatory conditions associated with neutrophil activation.
Analysis of Power Consumption on Communication Methods for the Emergency Deployment System

—Energy consumption phenomena of IOT based emergency deployment system which used in general hospitals and other institutions are analyzed. The system can treat real-time emergency messages between servers and mobile clients by using multiple communication methods. Especially in the hospital environment, in order to avoid patient anxiety caused by emergency situations, the system informs sends the emergency situation to the person who is to response the situation by using one-way broadcast communications. After that a two-way communications and indoor positioning methods are used to control and record the response processes.
Data Replication in Cloud Systems: A Survey

This paper presents a survey of data replication strategies in cloud systems. Based on the survey and reviews of existing classifications, we propose another classification of replication strategies based on the following five dimensions: i static vs. dynamic, ii reactive vs. proactive workload balancing, iii provider vs. customer centric, iv optimal number vs. dynamic adjustment of the replica factor and v objective function. Ideally, a good replication strategy must simultaneously consider multiple criteria: i the reduction of access time, ii the reduction of the bandwidth consumption, iii the storage resource availability, iv a balanced workload between replicas and v a strategic placement algorithm including an adjusted number of replicas. Therefore, selecting a data replication strategy is a classic example of multiple criteria decision making problems. The taxonomy we present can be a useful guideline for IT managers to select the data replication strategy for their organization.
Adorno, culture and feminism

PART ONE: CRITICAL SOCIAL THEORY: AESTHETICS AND POLITICS Adorno and Women - Maggie O'Neill Negative Dialects, Kulturkritik and Unintentional Truth Adorno, Benjamin and the Aura - Shierry Weber Nicholsen An Aesthetics for Photography? The Encoding of History - Silvia L L[ac]opez Thinking Art in Constellations Fremdw[um]orter as 'The Jews of Language' and Adorno's Politics of Exile - Sinkwan Cheng PART TWO: FEMINISM, CULTURE AND SOCIETY: THE RELEVANCE OF CRITICAL THEORY FOR CONTEMPORARY FEMINISMS Critical Theory as a Critique of Society - Regina Becker-Schmidt Theodor W Adorno's Significance for a Feminist Sociology Fragile Foundations, Strong Traditions, Situated Questioning - Gudrun Axeli Knapp Critical Theory in German-Speaking Feminism Adorno - Juliet Flower MacCannell The Riddle of Femininity Of Music and Mimesis - Barbara Engh Mimesis, Dwelling and Architecture - Hilde Heynen Adorno's Relevance for a Feminist Theory of Architecture