Miracle-dz/UniFAR-FTUs huggingface dataset:
Automatic Vehicle-Pedestrian Conflict Identification With Trajectories of Road Users Extracted From Roadside LiDAR Sensors Using a Rule-Based Method

Vehicle-pedestrian conflicts have been the major concern for traffic safety. Surrogate safety measures are widely applied for pedestrian safety evaluation. However, how to quickly identify the vehicle-pedestrian surrogate safety measures at the individual site is challenging due to the difficulty of obtaining the high-resolution trajectories of road users. This paper presented an effective method to generate the high-resolution traffic trajectories from the roadside deployed Light Detection and Ranging (LiDAR) sensor. The vehicle-pedestrian conflicts can then be identified from the trajectories simply using the speed-distance profile (SDP) of the vehicles. The SDP can be used to develop a rule-based method for vehicle-pedestrian identification. The events can be divided into different risk levels based on the spatial distribution of the SDP. The case study shows that the rule-based method can detect vehicle-pedestrian near-crash events effectively. The other indicators, such as widely used time-to-collision (TTC) or deceleration rate to avoid a crash (DRAC), can be also obtained from the SDP. The engineers can also adjust the thresholds in the rule-based method to meet the specific requirements at different sites. The proposed method can be extended to identify vehicle-vehicle conflicts or vehicle-bicycle conflicts in future studies.
Analysis of Impervious Surface Change and Economy in Tianjin, China Using Landsat Time Series Data

Tianjin city, China has seen rapid urban expansion and economy development especially since the Chinese reform and opening up in 1978. Understanding their internal relationship is important for urban management. Considering of the long-history records with medium spatial resolution (30 meters), Landsat time series (LTS) has become a key remote sensing dataset for monitoring urban changes. As the impervious surface is an important indicator for assessing urban environment, in this study, we extracted the impervious surface maps in Tianjin between 1990 and 2017 based on LTS using a Continue Change Detection and Classification (CCDC) algorithm. On the other hand, we quantitatively explored the relationships between the impervious surface and Gross National Product (GDP). Results show that the impervious surface expansion in Tianjin experienced two stages between 1990 and 2017 with the area increased by 521.95 km2, and the correlation coefficient between the area of impervious surface and GDP value was as high as 0.9718.
Role of actin in organelle trafficking in neurons

Actin is a major cytoskeletal element involved in multiple cellular processes. Actin‐rich regions present along the neuronal process aid in neuronal function, mediating multiple events involved in organelle trafficking. Actin is involved in organelle biogenesis, transport, and anchoring at specific locations. These functions can potentially be regulated by actin in a myosin‐dependent or myosin‐independent manner. The actin network could aid in membrane remodeling through membrane constriction, motor dependent transport, polymerization‐based transport, cargo anchoring, and halting of cargo by acting as a physical barrier. Additionally, actin dynamics is perturbed in some neurodegenerative diseases where it could impact organelle biogenesis, transport, or anchoring thereby contributing to progression of disease phenotypes. The role of actin and myosin in organelle trafficking is the primary focus of this review.
HIV care in Istanbul, Turkey: How far is it from the UNAIDS 90–90–90 targets?

The prevalence of human immunodeficiency virus (HIV) infection is low but it is steadily increasing in Turkey. In the current study, we aimed to assess the status of HIV infection management with the proposed 90–90–90 targets in a large HIV cohort in Istanbul, Turkey. The cohort included 2382 patients (2082 male, 300 female, mean age was 36.3 ± 11.3 years). Mean CD4 cell count was 399 cells/mm3 and HIV-RNA level was 576,235 copies/ml. According to the modeling by the Modeling tool of European Center for Diseases Control Software, 72 and 74% of all HIV patients had been diagnosed in 2016 and 2017, respectively (the first target). Among 2382 patients, 2191 (92%) were on antiretroviral therapy (the second target). The third target of virally suppressing those on treatment was achieved among 70.2% of the patients. The current study suggests that both the fraction of those living with undiagnosed HIV and the proportion of those on treatment who are virally suppressed should be targeted to sustain optimal HIV care. Efforts should continue to surpass the targets of 90–90–90.
Hyperspectral Image Classification by Parameters Prediction Networks

Hyperspectral image, which contains high-resolution spectral information as well as large-scale spatial information, has been widely used in various classification applications of remote sensing area. However, due to the insufficient of the labeled samples in the training set and the unbalance of sample quantity between different classes, traditional supervised classification methods are difficult to achieve satisfying performance. In order to address above issues, this paper studies on how to predict classification parameters more effectively, and finds out that the parameters of the fully-connected layer in the classifier are closely related to the output of the feature mapping layer. Based on above fact, this paper proposes a hyperspectral image classification method base on parameter prediction network, which adapts a pre-trained neural network to novel categories by directly predicting the parameters of classifier from the feature data of the hyperspectral image. Experimental results and analysis demonstrate the competitive performance of the proposed method over other state-of-the-art classification methods based on neural network when the number of labeled samples is very small.
High Resolution SAR Image Synthesis with Hierarchical Generative Adversarial Networks

Generative adversarial network (GAN) is an artificial neural network based on unsupervised learning method. Due to its powerful model representation capabilities, GAN has been introduced to synthesize synthetic aperture radar (SAR) image data, for the real sample is difficult to acquire. Large-scale, high-resolution SAR images play an important role in promoting SAR applications, such as automatic target recognition and image interpretation. However, on account of the difficult training problem of GAN network, especially for SAR images with speckle noise, it is difficult to obtain high-resolution SAR images by simply transfer the net from optical image. Recent studies in other image fields have shown that hierarchical structure is an effective and useful way to decompose a generation task into several smaller subtasks. How to obtain more high-resolution SAR images from limited original samples through GAN is the target of our research. Therefore, in this paper, we introduce a hierarchical GAN network model to generate SAR images, through the multi-stage network, gradually improve the quality of the generated image, and finally obtain high-resolution images. The type and aspect of generated images are determined by the input of condition vectors in the last two stages. In addition, we introduce the triple loss, in which the background loss is used to imitating background clutter noise of SAR image, the condition loss is to make the generated images’ type and aspect become controllable, and the global loss for getting higher image generation quality. The generated images show high similarity with the real samples.
Multi-Band Propagation and Radio Channel Characterization in Street Canyon Scenarios for 5G and Beyond

Radio access at mm-waves has been subject of intensive research in the latest years. However, within the initial deployment of 5G, mm-waves are still relegated and there is a generalized idea that the mm-wave channel for radio access, in comparison to the sub-6 GHz channel, is not only sparse but also troublesome for outdoor applications. In the present paper we introduce simultaneous multi-band measurements comparing the sub-6 GHz with the mm-waves channel at 30 GHz and 60 GHz in street canyon scenarios using the same measurement equipment in Germany and Japan. An analysis on the propagation and radio channel characteristics shows that the mm-waves channel offers similar opportunities as the sub-6 GHz. Consequently, the challenge relies on the design of an adequate radio interface matching the channel characteristics. In that regard, aspects as the location of clusters and spatial consistency gain importance within geometry-based stochastic channel models (GBSCMs). The analysis of the large-scale parameters (LSPs) has shown a large influence of the geometry of the scenario on the channel, encouraging the introduction of deterministic modelling components within GBSCMs targeting these scenarios.
The Role of Daily High Dose Vitamin D In the Prevention of Post-Operative Vitamin D Deficiency In Children with Congenital Heart Disease

Background: Vitamin D deficiency (VDD) occurs in the majority of children following Congenital Heart Disease (CHD) surgery, and lower levels have been associated with postoperative cardiovascular dysfunction. Mechanistic studies have revealed that the high prevalence of VDD is due to poor pre-operative status and a 40% intraoperative drop in vitamin D. Available literature suggests that usual care with daily low dose vitamin D is ineffective and alternative regimens will be required to prevent post-operative VDD. Objectives: (1) To systematically review the pediatric clinical trial literature of high dose vitamin D, and (2) Determine whether pre-operative daily high dose vitamin D, based on the Institute of Medicine (IOM) Tolerable Upper Intake Level, can prevent post-operative VDD. Methods: (1) Systematic review Medline, Embase and the Cochrane Central Register of Controlled trials were searched for clinical trials reporting 25OHD levels in children after high dose vitamin D (≥ 1000 IU). Descriptive and meta-analysis techniques were used to determine the study characteristics associated with 25OHD response and adverse events. (2) Trial – Design and initiate a dose evaluation trial. Recruit sixty two children with CHD into a double blind RCT and randomly assign to receive pre-operative cholecalciferol as usual (< 1 yr: 400 IU, > 1 yr 600 IU) or high doses (< 1 yr: 1600 IU, > 1 yr: 2400 IU). Primary outcome is immediate post-operative 25OHD concentration. Secondary outcomes include vitamin D related adverse events and measures of trial feasibility. Study data to be reviewed by the Data Safety Monitoring Board after the first 30 participants this time point was also chosen for preparation of the thesis results (25OHD data not available). Results: (1) Systematic review – There were 88 eligible publications identified. Only two of six studies administering high dose daily supplementation (1000-4000 IU) to VDD children achieved group 25OHD levels above 75 nmol/L within 1 month; compared with nine of ten studies
Combinatory Multifactor Treatment Effects on Primary Nanofiber Oligodendrocyte Cultures

Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative disease of the central nervous system. Neurological deficits are attributed to inflammatory demyelination, which compromises axonal function and survival. These are mitigated in experimental models by rapid and often complete remyelination of affected axons, but in MS this endogenous repair mechanism frequently fails, leaving axons increasingly vulnerable to the detrimental effects of inflammatory and metabolic stress. Understanding the molecular basis of remyelination and remyelination failure is essential to develop improved therapies for this devastating disease. However, recent studies suggest that this is not due to a single dominant mechanism, but rather represents the biological outcome of multiple changes in the lesion microenvironment that combine to disrupt oligodendrocyte differentiation. This identifies a pressing need to develop technical platforms to investigate combinatory and/or synergistic effects of factors differentially expressed in MS lesions on oligodendrocyte proliferation and differentiation. Here we describe protocols using primary oligodendrocyte cultures from Bl6 mice on 384-well nanofiber plates to model changes affecting oligodendrogenesis and differentiation in the complex signaling environment associated with multiple sclerosis lesions. Using platelet-derived growth factor (PDGF–AA), fibroblast growth factor 2 (FGF2), bone morphogenetic protein 2 (BMP2) and bone morphogenetic protein 4 (BMP4) as representative targets, we demonstrate that we can assess their combinatory effects across a wide range of concentrations in a single experiment. This in vitro model is ideal for assessing the combinatory effects of changes in availability of multiple factors, thus more closely modelling the situation in vivo and furthering high-throughput screening possibilities.
Split Window Algorithm Calibration and Validation for TASI Sensor

In this work, we present the calibration and validation method we have applied in order to retrieve the split window (SW) coefficients for land surface temperature (LST) estimations from Thermal Airborne Spectrographic imager (TASI). For calibration and validation two different datasets has been used, both extracted from SeeBor V5.0 training dataset. The coefficients have been retrieved by a multiple regression analysis and MODTRAN simulations. For the radiative transfer experiment, we considered seven different viewing angles in a range between 0° and 60° with a step of 10°. Simulations have been performed considering all TASI channel combinations and the sensor spectral response functions. Preliminary results are presented for best band combinations suitable for SW algorithm application; these are channel 19 (10.034 gm) with 28 (11.024 gm), and channel 29 (11.134 gm) with 31 (11.354 gm). Finally, validation of the LST retrievals presents a RMSE lower than 0.6 K for both band combinations.
Case report: A patient coinfected by Borrelia burgdorferi sensu lato and spotted fever group Rickettsiae in Urumqi, China

Abstract Rationale: Both Borrelia burgdorferi sensu lato and spotted fever group Rickettsiae (SFGR) are pathogens carried by ticks. There is a possibility of co-infection with these tick-borne diseases. Patient concerns: Male patient, 63 years-of-age, admitted to hospital with skin rash presenting for 1 week and fever with cough and expectoration for 3 days before admission. Diagnoses: We diagnosed that the patient was co-infected by B burgdorferi sl and SFGR using laboratory test results and the patient's clinical manifestations. Interventions: The patient started therapy with oral minocycline, then levofloxacin by intravenous injection for SFGR. Meanwhile, he was treated with penicillin G sodium, cefoperazone sulbactam sodium and ceftriaxone by intravenous injection for B burgdorferi sl. Outcomes: After the patient was in stable condition, he was discharged from hospital. Lessons: This case report highlights the possibility of co-infection by 2 tick-borne diseases in Urumqi, Xinjiang Uygur Autonomous Region, China. The antibiotic therapy should be based on the detection of pathogenic bacteria, and the different susceptibilities of co-infecting bacteria should be considered.
Charting Self-Esteem During Marital Dissolution.

OBJECTIVE The purpose of this study was to chart changes in self-esteem before and after marital dissolution to identify the factors that shape individuals' self-esteem during this life transition. METHOD We analyzed 10 annual waves of self-esteem data from 291 divorcees from a nationally representative panel study of the Netherlands (N ~ 13,000). We charted the course of self-esteem before and after marital dissolution and tested a broad set of moderator variables that may shape individuals' self-esteem trajectories. RESULTS The average divorcee experienced significant decreases in self-esteem preceding marital dissolution and remained stable afterwards. There were substantial individual differences in self-esteem trajectories, both before and after marital separation. Divorcees who experienced financial hardship, were affiliated with a church or religion, or scored low in conscientiousness showed the most pronounced decreases in self-esteem during the years approaching marital dissolution. CONCLUSION This study highlights the importance of assessing people multiple times before and after marital dissolution to dissect how people approach and respond to this life event. Results are consistent with perspectives that view divorce as an opportunity to abate the strains of an unhappy marriage.
Multiple Mycotoxins Determination in Food by LC-MS/MS: An International Collaborative Study

An intercollaborative study was organized to evaluate the performance characteristics of a liquid chromatography tandem mass spectrometry procedure for the simultaneous determination of 12 mycotoxins in food, which were ochratoxin A, aflatoxins B1, B2, G1, G2, and M1, deoxynivalenol, zearalenone, fumonisins B1 and B2, and T-2 and HT-2 toxins. The method combined the simplicity of the QuEChERS (Quick, Easy, Cheap, Efficient, Rugged and Safe) approach with the efficiency of immunoaffinity column cleanup (the step used to enhance sensitivity and sample cleanup for some matrices only). Twenty-three entities were enrolled and were European reference laboratories for mycotoxin analysis, U.S. and European service laboratories, and Nestlé laboratories. Each participant analyzed 28 incurred and/or spiked blind samples composed of spices, nuts, milk powder, dried fruits, cereals, and baby food using the protocol given. Method performances were assessed according to ISO 5725-2. Relative standard deviations of repeatability and reproducibility and trueness values for each of the 115 mycotoxin/sample combinations ranged from 5% to 23%, 7% to 26%, and 85% to 129%, respectively, in line with requirements defined in EC 401/2006. The overall set of data gathered demonstrated that the method offered a unique platform to ensure compliance with EC 1881/2006 and EC 165/2013 regulations setting maximum limits for mycotoxins in food samples, even at low regulated levels for foods intended for infants and young children. The method was applicable regardless of the food, the regulated mycotoxin, and the concentration level, and thus is an excellent candidate for future standardization.
HUBUNGAN ANTARA PEMBERIAN ASI EKSLUSIF DENGAN RIWAYAT PENYAKIT INFEKSI PADA ANAK UMUR 1- 3 TAHUN DI DESA MOPUSI KECAMATAN L OLAYAN KABUPATEN BOLAANG MONGONDOW INDUK

Abstract : Infectious diseases are still major problems in many developing countries, including Indonesia. The effectiveness of exclusive breastfeeding is manifested in the reduction of specific disease incidences in infants who receive breast milk compared to formula -fed infants. This study used correlation method with a cross sectional design. Respondents were 90 women who had toddlers (aged less than 3 years) with histories of infectious disesases from September 2014 until Desember 2014. Data were obtained by using questionnaires. The results showed that there were as many as 23 toddlers (26%) with exclusive breastfeeding. History of infectious disease was found in 26 toddlers (28.9%). Regarding the relationship of exclusive breastfeeding with a history of infectious disease (α = 0.05) was found (p) = 0.001 and x2 = 11.883. There was a relationship between breastfeeding with a history of infectious disease in children aged less than 1-3 years in the Mopusi village, Lolayan Bolaang Mongondow Induk. Keywords : exclusive breastfeeding , history of infectious diseases , toddlers . Abstrak : Penyakit infeksi masih merupakan penyakit utama di banyak Negara berkembang, terutama Indonesia. Efektivitas ASI dalam mengendalikan infeksi dapat dibuktikan dengan berkurangnya kejadian beberapa penyakit spesifik pada bayi yang mendapat ASI di banding bayi yang mendapat susu formula. Penelitian ini bertujuan untuk mengetahui hubungan antara pemberian ASI ekslusif dengan riwayat penyakit infeksi pada batita di desa Mopusi kecamatan Lolayan kabupaten Bolaang Mongondow Induk. Penelitian ini menggunakan metode korelasi dengan pendekatan potong lintang. Responden ialah ibu yang memiliki batita dengan riwayat penyakit infeksi sebanyak 90 orang di desa Mopusi pada bulan September 2014-Desember 2014. Pengambilan data dengan menggunakan kuesioner. Hasil penelitian memperlihatkan sebanyak 23 batita (26%) mendapatkan ASI ekslusif. Riwayat penyakit infeksi ditemukan pada 26 batita (28,9%). Mengenai hubungan pemberian ASI ekslusif dengan riwayat penyakit infeksi (α = 0,05) didapatkan p = 0,001 dan x2 = 11,883. Simpulan: Terdapat hubungan antara pemberian ASI dan riwayat penyakit infeksi pada anak umur 1-3 tahun di desa Mopusi kecamatan Lolayan kabupaten Bolaang Mongondow Induk. Kata kunci : ASI ekslusif, riwayat penyakit infeksi, batita
Infective Endocarditis Complicated by Septic Pulmonary Emboli in a Case of a Ventricular Septal Defect

Introduction: Infective endocarditis (IE) causes serious complications in patients. Congenital heart disease (CHD) is an important underlying condition in children. Septic pulmonary embolism is an uncommon syndrome, and pulmonary valve IE is rare. The current study presented a case of right-sided IE with pulmonary valve involvement and its complications as pulmonary septic emboli in a child with CHD. Case Presentation: A 6-year-old girl with a ventricular septal defect (VSD) was presented. Echocardiography revealed large vegetation in the right ventricular outflow tract near the pulmonary valve. The patient showed clinical symptoms of lung involvement, and radiologic investigation was compatible with a diagnosis of septic pulmonary emboli. She had good response to antibacterial therapy and underwent a successful surgical closure of the heart defect. Conclusions: Children with CHD are at risk of severe complications with the involvement of other organs. long-term febrile illness should be taken seriously in these children. They need hospitalization and careful evaluation.
A Chart Review Study of Sexually Transmitted Infections Among Persons Living with HIV Attending an STI Clinic in Trinidad

A chart review study of the sexually transmitted infection (STI) prevalence among persons living with HIV (PLHIV) was conducted among STI clinic attendees in Trinidad between January 2012 and December 2012. Data were abstracted from client records to obtain the clinical and the laboratory diagnoses of STIs. Descriptive and bivariate analyses were conducted, and factors significantly associated with the presence of a STI were assessed using multiple logistic regression. During this period, 385 PLHIV were seen; 104 (27.0%) were newly HIV diagnosed and 281 (73.0%) had a known history of HIV infection; 135 (35.1%) were diagnosed with a STI. Patients with known HIV infection were more likely to be diagnosed with a STI than those who were newly diagnosed (odds ratios: 6.99; 95% confidence interval: 3.79-12.89). The STI prevalence was high among PLHIV in Trinidad, identifying them as a critical target group for public health interventions to prevent the spread of HIV and STIs.