Miracle-dz/UniFAR-FTUs huggingface dataset:
Role-Based Connectivity Management with Realistic Air-to-Ground Channels for Cooperative UAVs

Ad-hoc aerial sensor networks leveraging MUAVs (Micro Unmanned Aerial Vehicles) are ideally suited to cost-efficiently explore unknown or hostile environments for example in case of incidents producing harmful gases or radiation. In this manuscript we present results on the investigations of communication-aware steering algorithms for cooperative MUAV swarms. The mission objective is to achieve a maximum spatial exploration efficiency with the simultaneous ability to self-optimize the communication links by exploiting controlled mobility. While our previous work has mainly considered the performance of the Air-to-Air mesh network, in this paper we focus on the Air-to-Ground-link connectivity control. To achieve appropriate communication links to a central sensor data sink even while exploring larger search areas, an agent-based role management strategy is used to provide suitable multi-hop connectivity. The novel algorithms are investigated for static as well as dynamically changing environments. Key results include a detailed realistic aerial channel characterization and network dimensioning analysis considering numbers of MUAVs and density of ground stations vs. exploration speed and sensor data latency.
Phosphorylation of rat-thymus histone.

Ord & Stocken (1966) have shown that [32P]_ phosphate injected into rats is incorporated into the histones of the thymus gland. It has now been found that incorporation also takes place in vitro. Rat-thymus nuclei from six to eight rats of 120140g. body wt. were prepared as described by Ord, Raaf, Smit & Stocken (1965). These were suspended in 10ml. of the isolation medium (0-25M-sucrose-5mm-MgCl2-5mm-tris-HCl,pH7.2) to which was added 0-8ml. of 0.9% NaCl containing 100mg. of glucose/100ml. followed by 150,c of inorganic [32P]phosphate (specific activity 50c/mg. of P). At the end of the incubation period the nuclei were washed three times with 15ml. of medium and the histone fl was isolated by method 1 of Johns (1964). Reproducible incorporation into histone fl was obtained. The uptake was rapid, 50% of the activity obtained after 2hr. incubation being present in the histone after 20min. This uptake of [32P]phosphate was not inhibited by the addition of either actinomycin or puromycin to the incubation medium in concentrations of 100,g. /ml. , which indicates that the phosphorylation is not related to protein synthesis but is occurring on the preformed histone. It was also found that after a 1 hr. incubation period the phosphorus content ofhistone fl increases from 20-25 to 35-45miug.atoms of P/mg. of protein. This increase was followed over a 2hr. period in conjunction with a [32P]phosphate uptake timecourse and both were found to give the same pattern. Results are shown in Table 1. Analytical electrophoresis on polyacrylamide gels showed that the histone fraction fl isolated from these experiments in vitro gave the same strong single band as material from preparations in vivo. The nature of the 32p incorporation in these studies in vitro was investigated. Ord & Stocken (1966) have shown that 32p incorporated in vivo is present in the protein as serine phosphate. A 3mg. sample of histone fraction fl from a 32p_ incorporation experiment in vitro was hydrolysed for 3hr. at 1000 in 6N-HCI, and after removal of the HCI in vacuo overKOH the hydrolysed material was dissolved in water and examined by ascending paper chromatography with 2-methylpropan-2-olbutan-2-one-water-aq. NH3 (sp.gr. 0.88) (4:3:2: 1, by vol.) (Fink, Cline & Fink, 1963). This system gives clear separation ofserine and serine phosphate. The 32p had the same B. value as the serine phosphate marker. The eluate from the spot showing 32p activity was hydrolysed in 12N-HCI in vacuo for 17 hr. The solution was evaporated to dryness, dissolved in trimethylamine, treated with 1-fluoro2,4-dinitro[14C]benzene and the DNP-amino acids
Heart rate variability: An important new risk factor in patients following myocardial infarction

After acute myocardial infarction, cardiac autonomic, and particularly parasympathetic, activity decreases, followed by a gradual return toward normal over the next few weeks and months. The easiest measureable index of autonomic activity is heart rate variability, which can be assessed in a number of different ways. Where heart rate variability is low after myocardial infarction, long‐term survival is considerably reduced, independent of other known risk factors. This may be caused by patchy autonomic denervation, rendering the heart more susceptible to potentially fatal arrhythmias. Prophylactic drug therapy might reduce mortality in patients with low heart rate variability.
In Vitro Investigations of Two Types of Lupus Erythematosus Plasma Factor

The danger of producing an amniotic-fluid embolus as F result of the greatly increased uterine contractions has been proved. Barno and Freeman (1959) discussed 15 cases of maternal death due to amniotic-fluid embolus. In seven of these pitocin had been administered, twice by intravenous drip and five times by intramuscular injection. The use of intramuscular pitocin undiluted, in single or divided doses, for the induction or stimulation of labour should cease. If pitocin has to be used it should be given as an intravenous or intramuscular drip. Owing to the time and attention required by these drips it would seem unlikely that there is any place for them in domiciliary obstetrics. Whenever they are contemplated, it is worth while bearing in mind some of the following contraindications described by Greenhill (1945). Pitocin should never be administered where there is any possibility of obstructed labour, in malpresentation, or after a previous caesarean section. If it is given in labour it should only be for a true hypotonic inertia. It should be avoided in severe toxaemias and should never be used in a patient who has had more than four deliveries. Under no circumstances should a patient be left alone after the administration of pitocin. If contractions are prolonged or too frequent, or there is a change in the foetal heart rate, the administration of pitocin should be stopped, and it may be necessary to give a general anaesthetic in order to diminish the strength of the contractions. The most recent condemnation of intramuscular pitocin took place at the British Congress of Obstetrics and Gynaecology in July, 1959. To quote Wrigley (1959): "This Congress would render no disservice to the community if it declared its complete condemnation. of the practice of administration of pitocin by the method of repeated intramuscular injections. "
Effect of acute alpha adrenergic stimulation on cardiac function

Background. Phenylephrine (PE) is a α-adrenergic agent commonly administered by perfusion and anesthesia. It is important to identify the effect of PE, especially on cardiac function. This study was intended to show the effects of PE on cardiac function in the murine model via pressure-volume loops. Methods. Six C57BL/6J twelve-week-old female mice were studied prior to and following PE administration at 50 μg/kg IV. In vivo pressure-volume loops were recorded at both time points. Results. There was an expected increase in maximum arterial pressure by 30% (p < 0.001) and end-systolic pressure by 34% (p < 0.001). However, there was a decrease in cardiac output by 30% (p = 0.0006), ejection fraction by 36% (p = 0.0003) and stroke volume by 25% (p < 0.004). Conclusions. This study demonstrates that PE has an effect on cardiac function beyond increasing vascular resistance. The data suggest the negative effects of PE on cardiac function may be related to stimulation of cardiac α-adrenergic receptors. Perfusion (2007) 22, 289—292.
Family and Research Context of Internationally Adopted Child Abuse Fatalities

insightful commentaries of Drs. Gunnar and Pollak (this issue) and Barnett (this issue). We welcome further discussion of the important points that have been raised. Space limitations in our original letter precluded full presentation of the many complex aspects of the tragic (but fortunately, infrequent) problem of child abuse fatalities of international adoptees. We agree with Gunnar and Pollak that support for the adoptive families of troubled children is sadly lacking—not only in less-populated areas but also in urban areas with many professionals trained in adoption-related issues. Such children—and their families—require significant therapy and other interventions from experienced providers; many professionals with the requisite skills, expertise, and experience are overbooked and unable to handle the volume of demands for their services. Furthermore, the complex mental health and educational needs of many of the children do not usually fit neatly into the knowledge base of a single provider and, as stated by both commentators, many barriers exist to needed care coordination. Furthermore, billing and reimbursement issues can complicate or even prevent needed treatments for children with complicated, chronic conditions, especially mental health disorders. Pediatricians, teachers, and other professionals clearly must receive education—in their academic training and on an ongoing basis—about the issues involved because too few currently are competent to provide the support required for the families of children with specific, intricate emotional and behavioral needs related to adoption and complicated early lives. The systemic strengthening of support by adoption practitioners, school personnel, and other relevant professionals would indeed reduce stress for many of these families. It is important to note that, even with the current deficiencies, the vast majority of adoptive families facing such challenging situations display phenomenal dedication to and advocacy for their children. Although defense attorneys have claimed that several of the fatally injured children had severe behavioral issues, the evidence suggests that such boys and girls are not generally the targets for such cruelty. Rather, as in other cases of child abuse fatalities, parental isolation, inexperience, and emotional problems are more closely linked to this horrid outcome (Crittenden, 1985; Egeland, Breitenbucher, & Rosenberg, 1980). Indeed, children with severe behavioral disorders often have some level of community support services (albeit inadequate) that can mitigate against fatal abuse. It is striking that the children described in our letter were so young (67% were younger than age 3 years). Although challenging behaviors can certainly Family and Research Context of Internationally Adopted Child Abuse Fatalities
Copper oxide nanoparticles recruit macrophages and modulate nitric oxide, proinflammatory cytokines and PGE2 production through arginase activation.

AIM In the present study, we examine the effects of copper oxide nanoparticles (CuNP) on macrophage immune response and the signaling pathways involved. MATERIALS & METHODS A peritonitis model was used to determine in vivo immune cells recruitment, while primary macrophages were used as an in vitro model for the cellular and molecular analysis. RESULTS In vivo, CuNP induce significant macrophages recruitment to the site of injection. In vitro, in LPS-stimulated primary macrophages, the co-treatment with CuNP inhibited the production of NO in a dose-dependent manner. The mechanism underlying NO and proinflammatory cytokines inhibition was associated with an increased arginase activity. Macrophage stimulation with CuNP did not provoke any cytokine secretion; however, arginase inhibition promoted TNFα and MIP-1β production. In addition, CuNP induced the expression of COX-2 and the production of PGE2 through arginase activation. CONCLUSION Our results demonstrate that CuNP activate arginase and suppress macrophage innate immune response.
Chronic Stable Angina: Diagnosis and Risk Stratification

OBJECTIVES After participating in the CME activity, primary care physicians should be able to: 1. Develop a differential diagnosis for chest pain and recognize clinical features that require prompt attention 2. Recognize important clinical predictors that influence the pretest probability of significant coronary artery disease (CAD) 3. Understand the settings in which myocardial imaging studies are preferable to an exercise treadmill electrocardiogram test as an initial test to the establish the diagnosis of CAD 4. Recognize that noninvasive diagnostic testing is valuable in the setting of an intermediate pretest likelihood of significant CAD 5. Distinguish between noninvasive testing for the purposes of diagnosis versus risk stratification 6. Understand the clinical features of intermediateor high-risk stable angina that require further evaluation by coronary angiography
Immunotherapy for Non-small Cell Lung Cancer: Novel Approaches to Improve Patient Outcome

Introduction: Non-small cell lung cancer (NSCLC) is often diagnosed in advanced stages and is associated with poor outcomes. Existing standards of care for NSCLC result in low overall cure rates, suggesting that novel treatment approaches are needed. In this review, we provide an updated look at the clinical data on immunotherapeutic interventions, which potentiate the immune system's response to lung tumor cells. Methods: We searched articles on PubMed and abstracts from recent oncology meetings for publications on immunotherapies with clinical applicability to the treatment of NSCLC. Results: Results from phase 2 trials show vaccine therapies, which target either tumor cells themselves or aberrantly expressed tumor markers (mucin 1, melanoma-associated antigen 3, or epidermal growth factor), may be promising immunotherapeutics for NSCLC. Antigen-independent immunotherapies, such as anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibodies, talactoferrin alfa, and toll-like receptor 9 agonists, act on a stimulated immune system regardless of the tumor antigen and may be feasible interventions for metastatic NSCLC. Several immunotherapies are undergoing phase 3 studies to assess optimal treatment settings and to determine clinical benefit compared with current standard treatments for NSCLC. Conclusions: A growing body of evidence suggests that immune responses to lung tumors are present. Immunotherapeutic interventions, including vaccine therapy and antigen-independent immunomodulatory strategies, may improve outcomes in NSCLC. Furthermore, treatments that enhance antitumor immune responses may prove to be synergistic with chemotherapy. Identification of biomarkers and further elucidation of immunotherapeutic mechanisms of action will be essential in determining which patients will experience the greatest benefit from immunotherapy.
Evaluation of the Vitek Immunodiagnostic Assay System (VIDAS) for the detection of Salmonella in foods

A Salmonella Assay using the Vitek Immunodiagnostic Assay System (VIDAS) was compared with a conventional cultural method (CCM) for the detection of salmonellas in 141 samples of artificially and naturally contaminated foods. There was an overall agreement of 92.9% between the methods. The productivity of the VIDAS Salmonella Assay (VSA) was not improved using an alternative enrichment protocol for the detection of Salmonella in 12 raw meat samples.
Ethmocephaly caused by de novo translocation 18;21—prenatal diagnosis

Ethmocephaly is a rare anomaly associated with partial failure of cleavage of the prosencephalon. Morphologically, it is closely related to cyclopia. We present an extremely rare case of ethmocephaly diagnosed in utero and caused by an unbalanced de novo translocation 18;21. Copyright © 2003 John Wiley & Sons, Ltd.
On the deep structure of information systems

Abstract. The deep structure of an information system comprises those properties that manifest the meaning of the real‐world system the information system is intended to model. In this paper we describe three models we have developed of information systems' deep‐structure properties. The first, the representational model, proposes a set of constructs that enable the ontological expressiveness of grammars used to model information systems (such as the entity‐relationship model) to be evaluated. The second, the state‐tracking model, proposes four requirements that information systems must satisfy if they are to faithfully track the real‐world system they are intended to model. The third, the good‐decomposition model, proposes three necessary conditions that information systems must meet if they are to be well decomposed. The three models provide a theoretically based, structured way of evaluating grammars that are used to analyse, design and implement information systems and scripts that have been generated using these grammars to describe specific information systems.
Energy harvesting from human motion with piezo fibers for the body monitoring by MEMS sensors

Piezoelectric fibers composite materials can be effectively used as electro-mechanical transducers to harvest power from human body motion thanks to high flexibility and improved reliability compared to traditional piezoceramic sheets. In this work, the motions of elbow and knee joints are replicated with test bench at variable amplitudes and angular velocities to characterize a piezo fiber composite with polymeric matrix. The output power is compared with the electrical specifications of a simple wearable system for sensing human body parameters composed of MEMS accelerometer and temperature sensors.
The Design of a Multiprocessor Operating System

Evolving applications and hardware are creating new requirements for operating systems. Real-time systems, parallel processing, and new programming paradigms require large adaptive maintenance efforts to modernize existing operating systems. An alternative to such adaptive maintenance is to seek new operating system designs that exploit modern software engineering techniques and methodologies to build appropriately structured modular software. This paper describes an approach to constructing operating systems based on a class hierarchy and object-oriented design, and discusses the benefits and difficulties of realizing this design using C++.
Parent‐reported symptoms may not be adequate to define asthma control in children

Asthma guidelines have suggested that treatment decisions should be guided by indices of asthma control and not only by disease severity. In adults, symptom‐based asthma control parameters have been shown to predict exacerbations and health care services use (HSU). We hypothesize that defining asthma control using parent‐reported symptoms alone is not adequate in children.
Effects of Preoperative Skin Preparation on Postoperative Wound Infection Rates A Prospective Study of 3 Skin Preparation Protocols

Objective. To compare the effects of different skin preparation solutions on surgical-site infection rates. Design. Three skin preparations were compared by means of a sequential implementation Design. Each agent was adopted as the preferred modality for a 6-month period for all general surgery cases. Period 1 used a povidone-iodine scrub-paint combination (Betadine) with an isopropyl alcohol application between these steps, period 2 used 2% Chlorhexidine and 70% isopropyl alcohol (ChloraPrep), and period 3 used iodine povacrylex in isopropyl alcohol (DuraPrep). Surgical-site infections were tracked for 30 days as part of ongoing data collection for the National Surgical Quality Improvement Project initiative. The primary outcome was the overall rate of surgical-site infection by 6-month period performed in an intent-to-treat manner. Setting. Single large academic medical center. Patients. All adult general surgery patients. Results. The study comprised 3,209 operations. The lowest infection rate was seen in period 3, with iodine povacrylex in isopropyl alcohol as the preferred preparation method (3.9%, compared with 6.4% for period 1 and 7.1% for period 2; P = .002). In subgroup analysis, no difference in outcomes was seen between patients prepared with povidone-iodine scrub-paint and those prepared with iodine povacrylex in isopropyl alcohol, but patients in both these groups had significantly lower surgical-site infection rates, compared with rates for patients prepared with 2% Chlorhexidine and 70% isopropyl alcohol (4.8% vs 8.2%; P = .001). Conclusions. Skin preparation solution is an important factor in the prevention of surgical-site infections. Iodophor-based compounds may be superior to Chlorhexidine for this purpose in general surgery patients.
Online campaigning: an opening for the outsiders? An analysis of Finnish parliamentary candidates' websites in the 2003 election campaign

This article examines the campaign websites of the 2003 Finnish parliamentary candidates. By examining candidate-level online competition in the candidate-centred Finnish context, individual-level variables are brought to attention in explaining website uptake and how campaign sites are used by candidates in terms of functions and sophistication. The findings show that the distribution of the candidates' web presence was skewed towards an over-representation of major party candidates. Moreover, in predicting candidate website functions and sophistication, belonging to a major party was a strong predictor. Candidate competitiveness and incumbency were also found to be significant predictors. Nevertheless, the findings in the article indicate that the relevance of these political factors may be less significant than other factors, for example genre effects, in explaining candidate website content and presentation.
Breakthrough in quantum efficiency of bi-alkali photocathodes PMTs

Bi-alkali type photocathodes are commonly used in classical photomultipliers. They provide low noise and high blue and near UV sensitivity well matched to scintillation light. The first breakthrough enhancement of standard bi-alkali photocathodes brought to the market PMTs characterized by quantum efficiencies of 30 % at 400 nm. Through a detailed understanding of the creation process of the photocathode and its optimization PHOTONIS has successfully obtained a production process achieving an average quantum efficiency of 38 % for a PMT bi-alkali photocathode. Further enhancement of the PMTs quantum efficiency was obtained by utilizing a special tulip shaped PMT glass envelope to reflect back to the photocathode the light which initially passed through without interaction. This work reports on the spectral measurements of the new CLARITY XP family of PMTs and their performance in spectrometry with different scintillators.
The Absolute Bioavailability of Oral Melatonin

The absolute bioavailability of oral melatonin tablets was studied in 12 normal healthy volunteers. Subjects were administered, in a randomized crossover fashion, melatonin 2 mg intravenously and 2 and 4 mg orally. Blood was sampled over approximately eight (estimated) half‐lives. Both the 2 and the 4 mg oral dosages showed an absolute bioavailability of approximately 15%. No difference in serum half‐life was seen in any of the study phases. Oral melatonin tablets in dosages of 2 and 4 mg show poor absolute bioavailability, either due to poor oral absorption, large first‐pass metabolism, or a combination of both. Further studies examining larger doses, in an attempt to saturate first‐pass metabolism if it occurs, may be warranted.
Adult basic education

Adult Basic Education (ABE) offers free instruction to those aged 16 and older with academic and English language skill building needs who are not enrolled in K-12. The Adult Success Center on the third floor of the Roy F. Christensen Building (Building #48) in Pocatello as well as ISU outreach sites in American Falls, Blackfoot, and Soda Springs provide these services. ABE serves the seven counties of Bannock, Bear Lake, Bingham, Caribou, Franklin, Oneida, and Power. Education is a pathway to a better quality of life for all.