Miracle-dz/UniFAR-FTUs huggingface dataset:
Association between maternal anxiety in pregnancy and increased uterine artery resistance index: cohort based study

Abstract Objective: To investigate whether maternal anxiety in the third trimester is associated with an increased uterine artery resistance index. Design: Cohort based study. Subjects: 100 pregnant women, with a mean gestation of 32 weeks. Outcome measures: Self rating Spielberger questionnaire for state anxiety and trait anxiety, and uterine blood flow waveform patterns as assessed by colour Doppler ultrasound. Results: A significant association was found between uterine artery resistance index and scores for both Spielberger state anxiety and trait anxiety (rs=0.31, P<0.002 and 0.28P<0.005 respectively). Women with state anxiety scores >40 (n=15) had a higher mean uterine resistance index than those with scores —40 (mean difference with mean resistance index 24%, 95% confidence interval 12% to 38%; P<0.0001). Similarly, women with trait anxiety scores >40 (n=32) had a higher mean resistance index than those with scores —40, although to a lesser extent. The presence of notches in the waveform pattern produced by uterine artery blood flow was found in 4/15 (27%) women with high state anxiety scores compared with 4/85 (5%) with low anxiety scores (P<0.02). Conclusions: This study shows an association between maternal anxiety in pregnancy and increased uterine artery resistance index. It suggests a mechanism by which the psychological state of the mother may affect fetal development, and may explain epidemiological associations between maternal anxiety and low birth weight. The influence of maternal anxiety may be one mechanism by which the intrauterine environment contributes to later disease in offspring.
Differenzialdiagnose der rezidivierenden Polyposis nasi: Das Analgetika-Asthma-Syndrom

B ereits wenige Jahre nach der Patentierung der Acetylsalicylsaure im Jahre 1899 beschrieb man erste Intoleranzreaktionen und 1920 den ersten Todesfall durch einen Aspirin-induzierten Asthmaanfall. Schon 1922 berichteten Widal et al. erstmals vom Zusammentreffen von Aspirinsensitivitat, Asthma bronchiale und Polyposis nasi, der klassischen Aspirintrias (e1). Ziel dieser Arbeit ist es, das klinische Bild, die derzeitigen pathophysiologischen Uberlegungen und die therapeutischen Ansatze darzustellen. Dabei sollen auch die Unterschiede zu allergischen Erkrankungen deutlich werden. Die Autoren wollen hervorheben, dass Karenzmasnahmen den Verlauf der Erkrankung nicht beeinflussen, jedoch mit der adaptiven Desaktivierung und den Leukotrien-Rezeptorantagonisten gesicherte Behandlungsmoglichkeiten zur Verfugung stehen. Die Arbeit basiert auf einer selektiven Literaturrecherche mittels Handsuche sowie in Medline zuletzt am 8. Januar 2007 unter den Stichworten „aspirin sensitive asthma“, „analgetics induced asthma“, „leukotrienes“, „desensitization“, „lipoxygenase“, „cyclooxygenase“. Einbezogen wurden eigene klinische Daten.
Identification of Abnormalities in ECG Signal Using Neural Pattern Recognition Tool

: Identification of abnormal ECG now a day’s needed very efficient methods and techniques to give accurate result for heart problems. In this paper we have used more powerful tool i.e. Neural Pattern Recognition Tool to identify two types of abnormal ECG known as MIT-BIH Atrial Fibrillation ECG and MIT-BIH Malignant Ventricular ECG. Our proposed model gives 100% accuracy for Atrial Fibrillation and 83.33% accuracy for Malignant Ventricular ECG detection.
The Nature of Nutrition: A Unifying Framework from Animal Adaptation to Human Obesity. By Stephen J. Simpson and David Raubenheimer. xii + 239 pp. Princeton, NJ: Princeton University Press. 2012. $49.50 (cloth or ebook).

How can you change your mind to be more open? There many sources that can help you to improve your thoughts. It can be from the other experiences and also story from some people. Book is one of the trusted sources to get. You can find so many books that we share here in this website. And now, we show you one of the best, the the nature of nutrition a unifying framework from animal adaptation to human obesity.
Design and implementation of a novel lightweight soft upper limb exoskeleton using pneumatic actuator muscles

Stroke is the leading cause of disability and weakness in the UK and around the world. Thus, stroke patients require an extensive rehabilitation therapy to regain some of the weaknesses. Many rehabilitation robotic devices have been designed and developed to assist the stroke patients to perform their activities of daily living and to perform repetitive movements. However, these devices remain unmanageable to use by the patients alone not only because they are cumbersome to use but also due to their weights, rigid, fix and non-portable characteristics. Thus there is a need to invent a novel exoskeleton soft arm that has a lightweight and a high power to rehab the elbow joint with lower cost and without the need to therapists. Here for elbow joint rehabilitation, we investigate and propose a novel exoskeleton soft robotic arm, which is wearable, lightweight and portable so that it would allow patients to perform repetitive motion therapy more often with a greater intensity in their homes and relevant to their Activities of Daily Living (ADL). The proposed arm consists of various bending pneumatic muscle actuators (pMA), where traditional pMA are not suitable. Testing on various pMA (traditional and bending) revealed its behaviour and the relationship between pressure, length, force, and bending angle in different setups such as isotonic and isometric. Experiments are done to analyse its non-linear behaviour, moreover, geometrical and numerical models are compared to the experimental results to validate the results. A developed control approach to control the soft arm is implemented to validate the design. Model reference adaptive control (MRAC) to control the arm using (Proportional, Integral, and Derivative) PID controller as an input for MRAC. Neural Network (NN) is also used in MRAC to improve the performance of MRAC.
New perspectives for the treatment of the patient with sepsis

URL Sepsis represents 20% of admissions in non-cardiologic intensive care units (ICU) and has a high mortality rate. Even with the advances in antimicrobial and vasopressor therapy, mortality remains high. Thus, early diagnosis of sepsis is necessary to avoid septic shock, which is associated with a mortality rate of 40% or more(1). In 2016, the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM) published new definitions, simplifying the nomenclature of sepsis, defining it as life-threatening organic dysfunction caused by an unregulated response to infection. Septic shock is when sepsis occurs with the presence of hypotension, requiring vasopressor therapy to maintain mean blood pressure (MBP) ≥ 65 mmHg associate with lactate ≥ 2 mmol/L, after adequate fluid resuscitation(2). In response to the lack of improvement in the mortality of patients with sepsis, the same societies created the campaign Surviving Sepsis, which provided guidelines for the treatment of the disease worldwide. These guidelines were reviewed in May 2018 and underwent some changes. The main alteration was the proposal of the hour-1 bundle(3). The sepsis management bundle comprises a selected set of care actions that, when implemented as a group, can affect the clinical outcome and simplify the complex care process of these patients. Prior to the alterations, the campaign included two care bundles with the purpose of reducing mortality. The first was called 3-hour bundle and included measuring lactate levels, obtaining blood cultures prior to administration of antibiotics, administering broad-spectrum antibiotics and administering 30 mL/kg crystalloid in case of hypotension or lactate greater than or equal to 4 mmol/L. The purpose of this bundle was to prevent tissue hypoxia and hypoperfusion and, at the same time, to institute early antimicrobial therapy. The 6-hour bundle included the use of vasopressor therapy to maintain MBP greater than or equal to 65 mmHg, in the case of persistent hypotension, even after fluid replacement, with blood pressure less than 65 mmHg or lactate greater than or equal to 4 mmol/L.
Transmission Dynamics of Urogenital Schistosomiasis in the Rural Community of Ebonyi State, South Eastern Nigeria

This study accessed the dynamics of urogenital schistosomiasis transmission in Nkalagu Community. A total of 500 mid-day urine samples were collected and transported to Microbiology Laboratory, Ebonyi State University, for analysis. 10ml each of the urine samples was centrifuged at 2500 rpm for 5 minutes. Transmission potential of snail intermediate host of Schistosomes collected from different sampling station at the transmission sites within the study community was equally accessed. The snail species collected were placed individually into a clean beaker with little quantity of water and then subjected to shedding light for 2 hours. Data obtained were entered in excel spread sheet and analyzed using chi square test. The result obtained shows that 205 (41%) out of 500 individuals examined were excreting S. haematobium ova in their urine. The highest prevalence of infection (23%) was found among 11-20-year age groups. Males were more infected (25.4%) than their female counterparts (15.6%), although this was not statistically significant (p > 0.05). A total of 283 snails belonging to two Bulinus species (B. globosus and B. truncatus) were collected from the four sites sampled. Bulinus globosus recorded the highest species abundance (177) with the highest occurrence in site A. 52 (18.4%) out of 283 snails collected were infected with cercariae, and the highest cercariae infection (12.0%) was recorded among B. globosus. With prevalence of 41% among the human population and the prevalence of 18.4% patent infection among the snail intermediate hosts, urogenital schistosomiasis is still a public health problem in the study area and falls within the WHO classification of endemic area. Public health campaign is recommended in order to educate the people on the mode of transmission and control of the disease.
Analysis of two different luteal phase support regimes and evaluation of in vitro fertilization-intra cytoplasmic sperm injection outcomes

Objective: To evaluate clinical pregnancy rates, miscarriage rates, ongoing pregnancy rates, and in vitro fertilization-intra cytoplasmic sperm injection outcomes of gonadotropin releasing hormone agonist (GnRHa) administration compared with human chorionic gonadotropin (hCG) application for luteal phase support. Materials and Methods: A total of 456 patients were included in the study. The patients were divided into two groups according to luteal phase support type: in group 1 (n=158), single-dose triptorelin acetate 0.1 mg was given on the sixth day after the oocyte pick-up (OPU). In group 2 (n=298), hCG 1500 IU was given on day 4, 7 and 10 after the OPU. Results: Both groups were homogeneous in relation with age and antral follicle count. The number of stimulation days and endometrial thickness on hCG day (mm) were found to be significantly higher in group 2 than in group 1 (p<0.001). The clinical pregnancy rate was slightly higher in the GnRHa group, but this difference was not statistically significant. Conclusion: Although there was no statistically significant difference between the two groups, luteal phase support with single-dose GnRHa might be as efficient as three doses of hCG. Large prospective, randomized-controlled studies are required comparing GnRHa and hCG for luteal phase support.
Medium-term clinical outcomes of laminoplasty with adjunct short anterior fusion in multilevel cervical myelopathy

Objectives: Expansive open-door laminoplasty (EOLP) is effective for multilevel cervical spondylotic myelopathy (MCSM). When MCSM is combined with one- or two-level segmental kyphosis, instability, or major anterior foci, EOLP with short-segment anterior cervical fusion (ACF) results in good short-term neurological recovery and can preserve postoperative range of motion (ROM). The objective of this study was to evaluate the medium-term clinical outcomes of this procedure and to analyze the risk factors affecting the neurological function at the last follow-up. Materials and Methods: A total of 87 patients were enrolled in this retrospective study conducted from January 2007 to May 2011. These patients exhibited MCSM with combined short segmental kyphosis, instability, or major anterior pathology, and received EOLP and short-segment anterior fusion. The follow-up period lasted at least 60 months. The radiographic outcomes were collected from plain radiographs with dynamic views checked preoperatively and at the last follow-up. Neurological status and visual analog scale scores for neck pain were evaluated. Logistic regression analysis was then applied to determine the correlation between radiographic parameters and rates of neurological recovery. Results: The mean Japanese Orthopedics Association recovery rate at the last follow-up was 77.8%. The improvement in functional scores and reduction in neck pain were statistically significant. The most influential risk factor affecting neurologic recovery was preoperative functional status. Conclusions: EOLP followed by short-segment ACF is a favorable treatment for patients with MCSM with concomitant short-segment kyphosis, instability, or major anterior pathology.
Sexually Dimorphic Vasopressin Cells Modulate Social Investigation and Communication in Sex-Specific Ways

Abstract The neuropeptide arginine vasopressin (AVP) has long been implicated in the regulation of social behavior and communication, but precisely which AVP cell groups are involved is largely unknown. To address whether the sexually dimorphic AVP cell group in the bed nucleus of the stria terminalis (BNST) is important for social communication, we deleted BNST AVP cells by viral delivery of a Cre-dependent caspase-3 cell-death construct in AVP-iCre-positive mice using AVP-iCre negative littermate as controls, and assessed social, sexual, aggressive and anxiety-related behaviors. In males, lesioning BNST AVP cells reduced social investigation of other males and increased urine marking (UM) in the presence of a live female, without altering ultrasonic vocalizations (USVs), resident-intruder aggression, copulatory behavior, anxiety, or investigation of females or their odor cues. In females, which have significantly fewer AVP cells in the BNST, these injections influenced copulatory behavior but otherwise had minimal effects on social behavior and communication, indicating that these cells contribute to sex differences in social behavioral function.
Adherence to Iron-Folate Supplementation and Associated Factors among Pastoralist's Pregnant Women in Burji Districts, Segen Area People's Zone, Southern Ethiopia: Community-Based Cross-Sectional Study

Background Iron deficiency anemia among pregnant women is one of the most common public health problems in developing country particularly in Ethiopia. Iron/folic acid supplementation with optimal adherence is the main cost-effective strategy for prevention and control of iron deficiency anemia in pregnant women. However, level of adherence to iron/folic acid supplementation and its associated factors were not well identified in study area. Therefore, the aim of this study was to determine the level of adherence to iron/folic acid supplementation and associated factors among pregnant women in Burji Districts, southern Ethiopia. Methods A community-based cross-sectional study was conducted among 317 pregnant women in Burji Districts from March to April 2017 using interviewer administered questionnaires. Data were entered into Epi Info 3.5. 1 and exported to SPSS version 20.0 for analysis. Binary and multivariable logistic regression was used to identify factors associated with iron/folic acid supplementation. Adjusted odds ratio (AOR) with 95% confidence interval (CI) and p-value <0.05 were used to declare statistical significance. Results Among women participating in the study, 163(51.4%) were adherent to iron/folate acid supplementation. Factors significantly associated with adherence to iron and folic acid supplementation were maternal educational status (AOR: 2.47, 95% CI: 1.13-4.97), early registration for ANC (AOR: 2.49, 95% CI: 1.45 – 4.27), history of anemia during current pregnancy (AOR: 2.02, 95% CI: 1.09-3.72), and knowledge about iron and folic acid supplementation (AOR: 1.96, 95% CI: 1.02-3.76). Forgetfulness and fear of side effects were among the leading reasons of pregnant women for nonadherence to iron and folic acid supplementation. Conclusions This study revealed that adherence to iron /folic acid supplementation was found to be 51.4%. Maternal educational status, early registration for ANC, history of anemia during current pregnancy, and knowledge about iron and folic acid supplementation were significant factors associated with adherence to iron/folic acid supplementation among pastoralist's pregnant women. Therefore, anemia prevention strategy should include strengthening giving awareness, counseling, strengthening community health education, and participation in health programs which are necessary to improve the uptake of iron/folic acid supplements.
Hyperacute Paraplegia and Neurovascular (Immuno Vasculotoxic) Catastrophe of Nicolau Syndrome: Primum Non nocere

A case of Nicolau syndrome (NS) in a 36-year-old adult taking an unusual and devastating hyperacute irreversible paraplegia after an intramuscular injection of benzathine penicillin as a part of routine chemoprophylaxis of her rheumatic heart disease is reported. Although this syndrome is a considerably rare, iatrogenic and underappreciated dermatologic entity, we reiterate in this report, its extracutaneous systemic potential for a catastrophic neurovascular phenomenon and morbidity as well as its possible preventive measures. The apoplectiform onset of T10 flaccid areflexic paraplegia, with the cutaneous hallmark of “embolia cutis medicamentosa” was corroborated by magnetic resonance imaging evidence of centromedullary complete cord involvement from T10 to conus medullaris. Combination therapy with pulse methylprednisolone, low-molecular-weight heparin, and pentoxifylline infusion proved unsuccessful. The skin biopsy and direct immunofluorescence revealed features were consistent with NS with overlap features of leukocytoclastic vasculitis, hitherto not reported. The literature of this preventable and iatrogenic disorder is reviewed, and plausible etiology is discussed.
Frenectomy with conventional scalpel and Nd:YAG laser technique: A comparative evaluation

Background: Frenectomy is complete excision of the frenum attachment to the underlying bone. Conventional frenectomy with blade has been widely used; however, laser-assisted frenectomy is the most recent alternative. Aim: The present study aims to compare two methods of frenectomy for the pain experienced, intraoperative bleeding, healing outcome, and need for analgesics. Materials and Methods: Twenty patients with high labial frenum attachment requiring frenectomy were included in this study. Patients were randomly divided into Group A: scalpel group and Group B: neodymium-doped yttrium aluminum garnet (Nd:YAG) laser group. Visual Analog pain score, intraoperative bleeding, number of analgesics used, and healing outcome 3 months postoperatively were recorded. Results: Group B patients experienced less pain (P = 0.016), less bleeding (P = 0.016), and required fewer number of analgesics (P = 0.008). Healing outcome at 3 months showed no significant difference between the two groups (P = 0.095). Conclusion: Based on the results of this study, it can be concluded that Nd:YAG laser is an efficient and a more comfortable alternative to scalpel for frenectomy.
Struma Ovarii: A Report of Three Cases and Literature Review

Struma ovarii is a variant of mature cystic teratoma, with predominant thyroid element. Confirmatory diagnosis is by histopathology. It may mimic as ovarian malignancy in some. It may be associated with ascites in minority; even CA-125 has been found to be raised in some cases. We here report three cases – two operated for suspected ovarian malignancy in a postmenopausal female and one case operated for persistent benign ovarian cyst with raised CA-125 in a young female. In all histopathological diagnosis was a benign struma ovarii. It is difficult to diagnose these cases preoperatively as there are no specific clinical, radiological or serum markers for these rare tumors in the absence of thyroid biology abnormality. Most cases are diagnosed on histopathology. These benign tumors many times require extensive staging laparotomy for suspected ovarian malignancy in the absence of preoperative diagnosis. Prognosis is good for these tumors. Subtle radiological signs and a clinical suspicion can avoid extensive staging laprotomies in these patients.
A Telescoping View of Solute Architectures in a Complex Fluid System

Short- and long-range correlations between solutes in solvents can influence the macroscopic chemistry and physical properties of solutions in ways that are not fully understood. The class of liquids known as complex (structured) fluids—containing multiscale aggregates resulting from weak self-assembly—are especially important in energy-relevant systems employed for a variety of chemical- and biological-based purification, separation, and catalytic processes. In these, solute (mass) transfer across liquid–liquid (water, oil) phase boundaries is the core function. Oftentimes the operational success of phase transfer chemistry is dependent upon the bulk fluid structures for which a common functional motif and an archetype aggregate is the micelle. In particular, there is an emerging consensus that mass transfer and bulk organic phase behaviors—notably the critical phenomenon of phase splitting—are impacted by the effects of micellar-like aggregates in water-in-oil microemulsions. In this study, we elucidate the microscopic structures and mesoscopic architectures of metal-, water-, and acid-loaded organic phases using a combination of X-ray and neutron experimentation as well as density functional theory and molecular dynamics simulations. The key conclusion is that the transfer of metal ions between an aqueous phase and an organic one involves the formation of small mononuclear clusters typical of metal–ligand coordination chemistry, at one extreme, in the organic phase, and their aggregation to multinuclear primary clusters that self-assemble to form even larger superclusters typical of supramolecular chemistry, at the other. Our metrical results add an orthogonal perspective to the energetics-based view of phase splitting in chemical separations known as the micellar model—founded upon the interpretation of small-angle neutron scattering data—with respect to a more general phase-space (gas–liquid) model of soft matter self-assembly and particle growth. The structure hierarchy observed in the aggregation of our quinary (zirconium nitrate–nitric acid–water–tri-n-butyl phosphate–n-octane) system is relevant to understanding solution phase transitions, in general, and the function of engineered fluids with metalloamphiphiles, in particular, for mass transfer applications, such as demixing in separation and synthesis in catalysis science.