Miracle-dz/UniFAR-FTUs huggingface dataset:
3D Plate‐Lattices: An Emerging Class of Low‐Density Metamaterial Exhibiting Optimal Isotropic Stiffness

In lightweight engineering, there is a constant quest for low‐density materials featuring high mass‐specific stiffness and strength. Additively‐manufactured metamaterials are particularly promising candidates as the controlled introduction of porosity allows for tailoring their density while activating strengthening size‐effects at the nano‐ and microstructural level. Here, plate‐lattices are conceived by placing plates along the closest‐packed planes of crystal structures. Based on theoretical analysis, a general design map is developed for elastically isotropic plate‐lattices of cubic symmetry. In addition to validating the design map, detailed computational analysis reveals that there even exist plate‐lattice compositions that provide nearly isotropic yield strength together with elastic isotropy. The most striking feature of plate‐lattices is that their stiffness and yield strength are within a few percent of the theoretical limits for isotropic porous solids. This implies that the stiffness of isotropic plate‐lattices is up to three times higher than that of the stiffest truss‐lattices of equal mass. This stiffness advantage is also confirmed by experiments on truss‐ and plate‐lattice specimens fabricated through direct laser writing. Due to their porous internal structure, the potential impact of the new metamaterials reported here goes beyond lightweight engineering, including applications for heat‐exchange, thermal insulation, acoustics, and biomedical engineering.
The effect of training of the non-dominant knee muscles on ipsi- and contralateral strength gains

BACKGROUND: Although transfer of unilateral training has been quite widely explored, few studies have focused on gains achieved due to concentric isokinetic training of the non-dominant side. OBJECTIVE: To examine the effects of unilateral non-dominant (ND) isokinetic knee extension and flexion training at 60◦/s on ipsilateral and contralateral knee extension and flexion peak moment (PM) in active female population as well investigate the speed specificity nature of this protocol. METHODS: Thirty female were divided into two groups: experimental and control. The experimental group trained concentrically the ND flexors and extensors at 60◦/s according to the following protocol: 5–6 reps X 2–4 sets X 3d X 4w at 100% effort while PM at preand post-training was tested concentrically at 60 and 180◦/s. RESULTS: Significant (p < 0.05) increases in the extensors and flexors PM peak moment in both the trained and untrained limb were noted in the experimental group, ranging 19–27% and 12–17%, respectively. The effects were speed specific in the trained but not in untrained limb. No changes were noted in the PM of the control group. CONCLUSIONS: In physically active female population, concentric isokinetic training of the ND knee extensors and flexors at 60◦/s significantly increase the strength of these muscles at the trained and untrained limb. This cross-education was not speed specific and therefore may obviate the need to use a multiple speed protocol.
Valoración de la mucositis secundaria a tratamiento oncohematológico mediante distintas escalas: Revisión

La mucositis oral es la inflamacion que tiene lugar en el epitelio oral, a consecuencia de los tratamientos antineoplasicos tales como la radioterapia, la quimioterapia o el transplante de medula osea, siendo muy frecuente en los tratamientos de los procesos oncohematologicos. Las consecuencias de esta inflamacion, no solo afectan a la calidad de vida del paciente, sino que ademas puede suponer una limitacion en la aplicacion del tratamiento, asi como un aumento de la estancia hospitalaria y de los gastos terapeuticos. Un obstaculo principal a la hora de estudiar la mucositis, ha sido la falta de un sistema adecuado para su valoracion mediante el examen oral. Los metodos desarrollados para medir y cuantificar los cambios producidos en el epitelio oral, como consecuencia del tratamiento del cancer, van desde los mas sencillos, tales como escalas generales con cuatro o cinco grados de severidad que permiten relacionar la mucositis con el estado de salud oral, hasta llegar a las escalas especificas de tratamiento, en las que se distingue el tipo de tratamiento antineoplasico que dio lugar a la mucositis, pasando por las escalas de multiples variables, en las que se valoran distintos aspectos y se estudia su correspondencia con el estado de salud oral y su funcion, obteniendo una puntuacion global de severidad de la mucositis; es importante el establecimiento de una escala comun para la valoracion de la mucositis, no solo con fines clinicos sino tambien para la investigacion del grado de toxicidad de los distintos regimenes terapeuticos que dan lugar a mucositis.
Epidemiología de la salmonelosis no tifoidea en un hospital de Pontevedra (1994-1997)

BACKGROUND: Since data on non-typhoidal salmonellosis in our health care area are scarce, we undertook an epidemiological study covering a four year period (1994-1997). METHODS: Retrospective descriptive study carried out through review of the medical and clinical microbiologic records at Hospital Provincial de Pontevedra. Culture, isolation, identification, antibiotic susceptibility and serotypification were done according to usual Clinical Microbiology protocols. RESULTS: Along the period under study 459 cases of non-typhoidal salmonellosis were diagnosed. The relative incidence was higher among pediatric than adult patients. Between 1994-1996 top incidence was detected in August, while in 1997 another maximum was found in April, closely related to climatic variations. The most frequent serogroup was D, with an increase in serogroup B since 1996. We found 16 different serotypes, being the more frequent in decreasing order Enteritidis (87.2%), Typhimurium (3.6%) and Hadar (2.3%). This distribution shows differences with regard to other national series covering a similar period of time. The more frequently detected antibiotic resistance was to ampicillin (39.0% strains), ampicillin-sulbactam (17.6%) and nalidixic acid (5.9%). Neither 3rd-generation cephalosporines nor fluoroquinolones resistance was detected. Serotype Typhimurium was the most resistant. We found association between certain resistance patterns and serotypes Hadar, Paratyphi B and Typhimurium. Most diagnosed cases corresponded to acute gastroenteritis (95.6%). Patients under 3 and over 69 suffered more frequently from extraintestinal salmonellosis. CONCLUSIONS: The high incidence of alimentary toxinfection due to Salmonella spp. in our area should warrant strict epidemiological surveillance programmes to detect sources of infection, evaluate sanitary control measures and use of antibiotics.
Novel Double-negative Feedback Loop between Adenomatous Polyposis Coli and Musashi1 in Colon Epithelia*

Loss of tumor suppressor adenomatous polyposis coli (APC) is thought to initiate the majority of all colorectal cancers. The predominant theory of colorectal carcinogenesis implicates stem cells as the initiating cells. However, relatively little is known about the function of APC in governing the homeostasis of normal intestinal stem cells. Here, we identify a novel double-negative feedback loop between APC and a translation inhibitor protein, Musashi1 (MSI1), in cultured human colonocytes. We show APC as a key factor in MSI1 regulation through Wnt signaling and identify APC mRNA as a novel target of translational inhibition by MSI1. We propose that APC/MSI1 interactions maintain homeostatic balance in the intestinal epithelium.
Particulate Matter Emitted from Gravel Crushers and Their Health Impacts on Workers, Middle Governorate - Gaza, Palestine

Case-control study was conducted during the period from April to August 2013 on all gravel crushers at Middle Gaza Governorates. 87 individuals participated, case (exposed) and control (non exposed) groups contain 40, 47 respectively. PM10 concentration level was measured in the six crushers, and all participants were subjected to questionnaire and vital signs measuring. Conducted to evaluate the level of PM10 air pollution in crushers plants, and their impacts on respiratory system health, vital signs for crushers workers. Results showed that an average of particulate matter contributions is 15153 μg/m 3 , which is about 100 times higher than PM10 existing standard of 150 μg/m 3 . As well as, it showed clear links between PM10 exposure and respiratory health and vital signs among exposed group. Cough, dyspnea and sputum buildup were more common among the exposed group 100%, 97.5%, and 82,5% respectively, the non exposed group 14.9%, 31,9%, and 28.6%, respectively. Vital signs disturbances (Increasing systolic and diastolic blood pressure, increasing pulse rate, increasing respiratory rate and temperature) reported significantly among the exposed workers. We can conclude that PM10 concentration level in crushers plants were much higher than the existing standard. Occupational exposure to PM10 leads to higher prevalence of respiratory symptoms and vital signs disturbance. Key Words: PM10. Respiratory symptoms. Vital signs. Crushers, Blood Pressure, Pulse, Temperature.
Falling in Old Age: Prevention and Management

Falling is one of the most common causes of disability in later life and is also one of the most preventable. This book provides an enormous body of fall-related research that has been organized by the author into easy, digestible information for geriatric health professionals. Extensively updated and revised for its second edition, the book has direct clinical applications and strategies for preventing and managing falls. It also contains new information on the physical, psychological, and social complications of falling. For physicians, nurses, administrators, and staff in long-term and other geriatric care settings, this book will be an essential resource.
Cancerrelateret fatigue - en udfordring for sygeplejen

I forskningsprojektet “Hverdagslivet med bivirkninger af kræftbehandling – patienters oplevelse af mestring vha. information og vejledning” (1) fremgik det, at cancerrelateret træthed “fatigue” (CRF) var oplevet som en alvorlig bivirkning, der influerede betydeligt på patienternes liv. I denne artikel løftes disse data frem, og der sættes fokus på, hvorledes patienterne beskrev og håndterede denne bivirkning.
How to Practice Evidence-based Psychiatry: Basic Principles and Case Studies

Contributors. Disclosure of interests. Foreword. Preface. Cautionary statement. Acknowledgements. Part I: Basic Principles of Evidence-Based Psychiatry. What is evidence-based psychiatric practice? The 5-step evidence-based medicine model. Asking answerable questions. Searching for answers. Clinical trials. Systematic reviews and meta-analyses. Clinical practice guidelines. Measurement. Diagnostic tests. Surveys of disease frequency. Studies of risk or harm. Studies of prognosis. Evaluating your performance of evidence-based medicine. Evidence-based psychiatric practice. Teaching evidence-based medicine and evidence-based psychiatry practice to psychiatry residents. Part II: Case Studies: Evidence-Based Medicine Applied to Major DSM-IV Disorders. Introduction to the cases. Panic disorder. Major depressive disorder and bulimia nervosa. Depression, refusal to eat, and nasopharyngeal carcinoma. Anorexia, obsessive-compulsive disorder, and depression. Major depressive disorder: a measurement-based care approach. Major depressive disorder, severe with psychotic features. Acute bipolar depression. Obsessive-compulsive disorder. Schizophrenia: a family psychoeducational approach. Substance use disorder presenting as a mood disorder. A complex personality disorder case. Bulimia nervosa. Part III: Case Studies: Evidence-Based Psychiatric Practice in Different Settings. Dual diagnosis (PTSD/SUD) treated in Veterans Affairs health care facility. Severe and recurrent depression managed in a remote setting via the Internet: an example of remote care using the HealthSteps system. Postpartum depression treated in private practice. Bipolar disorder treated in the Kaiser Permanente health care system. Consultation-liaison psychiatry. Alcohol dependence treated by a psychiatry resident. Appendix A: glossary. Appendix B: statistical formulas and tables. Index.
The use of stacked T-plating in dogs

Summary Dogs with fractures of the distal femur (one case), ilium (two cases) and a corrective osteotomy of the distal tibia (one case) underwent internal fixation using two 3.5-mm T-plates, applied in stacked fashion. Due to the specific configuration of the fractures as well as the size of the dogs, stacked T-plating was considered the most reliable technique to achieve satisfactory repair. All of the cases had “excellent” to “good” outcomes. The clinical experience with these four cases supports the utility of stacked T-plating in fractures with one very short end fragment. Stacked T-plating seems to have distinct advantages over a single 3.5-mm dynamic compression plate. However, due to the small number of cases presented in this report, there is a need for further clinical evaluation and biomechanical studies.
AN ANALYSIS OF DIRECT CAUSES OF MATERNAL MORTALITY

Objective: This study was conducted to analyze the direct causes of maternal mortality during a period of seven years in a tertiary care hospital of NWFP. Material and Methods: This retrospective, analytic study was conducted from 1998-2004, and included all the pregnant patients including miscarriage and ectopic pregnancies, presenting during this period to Gynae B Unit, Lady Reading Hospital Peshawar. The records of maternal deaths were reviewed from 1998- 2004 retrospectively and causes of direct deaths were analyzed. Deaths in non-pregnant patients and indirect deaths in pregnant patients were excluded. Results: Total number of live births during the time period was 23720 and total number of maternal deaths was 311. The maternal mortality ratio (MMR) was calculated as 1311/100,000 live births. Out of 311 maternal deaths, 268 (86.2%) had direct causes and 43 (13.8%) had indirect causes of maternal mortality. Haemorrhage was responsible for 42.16% (113/268) of maternal deaths, followed by hypertensive disorders in 24.63% (66/268), ruptured uterus in 10.45% (28/268), septicemia in 9.7% (26/268), thrombo-embolism in 7.8% (21/268) and unsafe abortion in 3.4% (9/268) cases. Conclusion: The study shows a very high MMR as compared to national figures. The leading cause of direct maternal death was hemorrhage, followed by pregnancy induced hypertension, ruptured uterus and septicemia. These conditions can be prevented by good antenatal, intranatal and postnatal care.
The Arabidopsis N-Acetylornithine Deacetylase Controls Ornithine Biosynthesis via a Linear Pathway with Downstream Effects on Polyamine Levels

Arabidopsis thaliana At4g17830 codes for a protein showing sequence similarity with the Escherichia coli N-acetylornithine deacetylase (EcArgE), an enzyme implicated in the linear ornithine (Orn) biosynthetic pathway. In plants, N-acetylornithine deacetylase (NAOD) activity has yet to be demonstrated; however, At4g17830-silenced and mutant (atnaod) plants display an impaired reproductive phenotype and altered foliar levels of Orn and polyamines (PAs). Here, we showed the direct connection between At4g17830 function and Orn biosynthesis, demonstrating biochemically that At4g17830 codes for a NAOD. These results are the first experimental proof that Orn can be produced in Arabidopsis via a linear pathway. In this study, to identify the role of AtNAOD in reproductive organs, we carried out a transcriptomic analysis on atnaod mutant and wild-type flowers. In the atnaod mutant, the most relevant effects were the reduced expression of cysteine-rich peptide-coding genes, known to regulate male–female cross-talk during reproduction, and variation in the expression of genes involved in nitrogen:carbon (N:C) status. The atnaod mutant also exhibited increased levels of sucrose and altered sensitivity to glucose. We hypothesize that AtNAOD participates in Orn and PA homeostasis, contributing to maintain an optimal N:C balance during reproductive development.
Takotsubo, discinesia apical transitoria: Presentacion de 4 casos y revisión de la literatura

: A syndrome of apical ballooning, with ECG mimicking acute myocardial infarctation, mild or no enzymatic changes, and normal coronary angiogram was described in 1990. It presents mainly in middle aged and elderly women and it is preceded by stress triggering circumstances. Several mechanisms have been proposed although the precise cause remains unclear. The most accepted theory proposes the interaction of catecholamines and an inadequate inotropic response. We report four cases that presented with chest pain and sudden onset of heart failure, all patients had physical or emotional stress as a triggering factor. On ECG, ST segment elevation and inverted T waves were observed in the acute phase. All patients had typical echocardiogram image and normal coronary angiogram. Both ECG and echocardiogram returned to normal within two weeks.
The reporting of cervical cancer in the mass media : a study of UK newspapersecc

Cervical cancer disproportionately affects those in lower socio-economic groups. Mass media, including newspapers, are an important source of information about disease and how to prevent it. An analysis of UK national newspaper content between 2000 and 2009 is reported, assessing the extent to which information is provided about early signs and symptoms, risk factors and ways of preventing cervical cancer. The messages in newspapers targeted at readers in lower socio-economic groups are compared with the messages in other newspapers, and the impact of reporting the illness and death of the reality TV star, Jade Goody, on the level of medical information contained in articles is assessed. Tabloid or ‘popular’ newspapers are found to provide more information about early signs and symptoms, and no less information about risk factors, when compared with broadsheets or ‘serious’ papers. This is due to their greater use of personal stories of people with cervical cancer. The Jade Goody story was associated with an increase in information about early signs and symptoms, and about screening, but not (with the exception of the role played by social deprivation) about risk factors. Suggestions about how to approach public education via an entertainment format in mass media are made.
Inducible Transposition of a Heat-Activated Retrotransposon in Tissue Culture

A transposition of a heat-activated retrotransposon named ONSEN required compromise of a small RNA-mediated epigenetic regulation that includes RNA-directed DNA methylation (RdDM) machinery after heat treatment. In the current study, we analyzed the transcriptional and transpositional activation of ONSEN to better understand the underlying molecular mechanism involved in the maintenance and/or induction of transposon activation in plant tissue culture. We found the transposition of heat-primed ONSEN during tissue culture independently of RdDM mutation. The heat activation of ONSEN transcripts was not significantly up-regulated in tissue culture compared with that in heat-stressed seedlings, indicating that the transposition of ONSEN was regulated independently of the transcript level. RdDM-related genes were up-regulated by heat stress in both tissue culture and seedlings. The level of DNA methylation of ONSEN did not show any change in tissue culture, and the amount of ONSEN-derived small RNAs was not affected by heat stress. The results indicated that the transposition of ONSEN was regulated by an alternative mechanism in addition to the RdDM-mediated epigenetic regulation in tissue culture. We applied the tissue culture-induced transposition of ONSEN to Japanese radish, an important breeding species of the family Brassicaceae. Several new insertions were detected in a regenerated plant derived from heat-stressed tissues and its self-fertilized progeny, revealing the possibility of molecular breeding without genetic modification.
Periodontitis in Man and Other Animals: A Comparative Review

Drug Dosage The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulatiOns, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Unconventional Nanofabrication for Supramolecular Electronics

The scientific effort toward achieving a full control over the correlation between structure and function in organic and polymer electronics has prompted the use of supramolecular interactions to drive the formation of highly ordered functional assemblies, which have been integrated into real devices. In the resulting field of supramolecular electronics, self‐assembly of organic semiconducting materials constitutes a powerful tool to generate low‐dimensional and crystalline functional architectures. These include 1D nanostructures (nanoribbons, nanotubes, and nanowires) and 2D molecular crystals with tuneable and unique optical, electronic, and mechanical properties. Optimizing the (opto)electronic properties of organic semiconducting materials is imperative to harness such supramolecular structures as active components for supramolecular electronics. However, their integration in real devices currently represents a significant challenge to the advancement of (opto)electronics. Here, an overview of the unconventional nanofabrication techniques and device configurations to enable supramolecular electronics to become a real technology is provided. A particular focus is put on how single and multiple supramolecular fibers and gels as well as supramolecularly engineered 2D materials can be integrated into novel vertical or horizontal junctions to realize flexible and high‐density multifunctional transistors, photodetectors, and memristors, exhibiting a set of new properties and excelling in their performances.