Miracle-dz/UniFAR-FTUs huggingface dataset:
Short forms of the Schedule for Nonadaptive and Adaptive Personality (SNAP) for Selfand Collateral Ratings: Development, Reliability, and Validity

Researchers and clinicians alike increasingly seek brief, reliable, and valid measures to obtain personality trait ratings from both selves and peers. We report the development of a paragraph-descriptor short form of a full-length personality assessment instrument, the Schedule for Nonadaptive and Adaptive Personality (SNAP) with both selfand other versions. Reliability and validity data were collected on a sample of 294 college students, from 90 of whom we also obtained parental ratings of their personality. Internal consistency reliability was good in both selfand parent data. The factorial structures of the self-report short and long forms were very similar. Convergence between parental ratings was moderately high. Self-parent convergence was variable, with lower agreement on scales assessing subjective distress than those assessing more observable behaviors; it also was stronger for higher order factors than for scales.
On the Variations of the Muscle Flexor Digitorum Brevis: Anatomical Insight

El musculo flexor corto de los dedos, es un musculo intrinseco de la planta del pie que frecuentemente presenta variaciones anatomicas. La variacion mas frecuente es la ausencia de tendon destinado al dedo minimo. Desde el punto de vista clinico se utilizan colgajos musculocutaneos del musculo flexor corto de los dedos para la reconstruccion de la region subcalcanea. Ademas, el tendon del musculo es usado para corregir deformidades de garra y martillo de los dedos del pie. A pesar de su importancia, es escasa la informacion acerca de este musculo en la poblacion adulta de Sri Lanka.Fueron disecados 135 pies humanos aparentemente sanos analizandose sus caracteristicas morfologicas. Se determino que un 71,85% el tendon para el quinto dedo del musculo flexor corto de los dedos estaba ausente. En todos los casos, esta se presentaba bilateralmente. El estudio senala la importancia de tener un cabal conocimiento acerca de las variaciones anatomicas del musculo flexor corto de los dedos, para facilitar tanto las tecnicas quirurgicas, como el diagnostico a traves de imagenlogia del pie. Ademas, un buen conocimiento de la arquitectura muscular del pie puede ayudar en el diseno de protesis y en el analisis de la funcion del pie.
Health in the Neighborhood and Household Contexts Among Older Chinese Americans

Objective: This study examined the associations of neighborhood characteristics and living arrangements with physical and mental health among older Chinese Americans. Method: A sample of 3,159 community-dwelling Chinese older adults in the Greater Chicago area provided reports of health, socio-demographic characteristics, living arrangements, social cohesion, and neighborhood disorder. We used multinomial logistic, Poisson, and negative binominal regression analyses. Results: Neighborhood disorder was consistently associated with negative health indicators, including poor self-reported health, more chronic conditions, depressive symptoms, and anxiety symptoms. Findings about the relationships between social cohesion and health indicators were mixed. Social cohesion was more salient to mental health for those living with spouse, children, and/or grandchildren relative to those living with spouse only. Discussion: Policies and interventions are needed to improve the physical and social environments of neighborhoods and to promote healthy aging among Chinese older adults and in the general population as well.
A Media Tracking and News Recommendation System

Nowadays, the amount of documents on internet resources is increasing at an unprecedented speed and users are tired of searching important and related ones among enormous amount of documents. Users require a personalized support in sifting through large amounts of available information according to their interests and recommendation systems try to answer this need. In this context, it is crucial to offer user friendly tools that facilitate faster and more accurate access to articles in digital newspapers. In this paper, a time-based recommendation system for news domain is presented. News articles are recommended according to user dynamic and static profiles. User dynamic profiles reflect user past interests and recent interests play much bigger roles in the selection of recommendations. Our recommendation system is a complete content-based recommendation system together with categorization, summarization and news collection modules.
The Selective Estrogen Receptor Modulator 4‐Hydroxy Tamoxifen Induces G1 Arrest and Apoptosis of Multiple Myeloma Cell Lines

Abstract: Multiple myeloma (MM) is an incurable hematological malignancy for which new therapeutic strategies should be envisaged. The selective estrogen receptor modulator (SERM), 4‐hydroxy tamoxifen (4‐OHTam), in the range of 1 to 10 μM, was able to impair the cell proliferation of MM cell lines. This was achieved by blocking cells at the G1 phase of the cell cycle and by inducing apoptosis. This cellular response was observed in five out of six tested cell lines, all five expressing both α and β estrogen receptor forms. No modifications of Bcl‐2, Bcl‐X, and Bax levels were observed, as well as no changes in Pi3K/Akt and JAK/STAT pathways that are often constitutively active in these cells. The signalization of 4‐OHTam‐induced cell death needs further investigation.
Occupational Kneeling and Meniscal Tears: A Magnetic Resonance Imaging Study in Floor Layers

Objective. To evaluate the association between occupational kneeling and degenerative meniscal tears. Methods. Magnetic resonance imaging (MRI) of both knees was conducted in 92 male floor layers and 49 male graphic designers (referents), with a mean age of 55.6 years (range 42–70 yrs). The presence of grade 3 MRI signal intensities indicating degenerative tears of the anterior, middle, and posterior one-third of the lateral and medial menisci was assessed on 1.5-Tesla MRI scans. The odds ratio (OR) of meniscal tears was determined among floor layers compared to graphic designers. Using logistic regression, models were adjusted for age, body mass index, and knee-straining sports. Results. Degenerative tears were significantly more prevalent in the medial meniscus among floor layers than among graphic designers [OR 2.28, 95% confidence interval (CI) 1.10–4.98] and significantly more floor layers had medial tears in both knees (OR 3.46, 95% CI 1.41–8.48). Tears extending to the tibial aspect and localized in the middle and posterior one-third of the medial meniscus were most prevalent. Lateral meniscal tears were predominantly unilateral and the prevalence of lateral tears did not differ between the 2 study groups. Knee complaints occurred in about 50% of all floor layers, irrespective of the presence of meniscal tears. Conclusion. Occupational kneeling increases the risk of degenerative tears in the medial but not the lateral menisci in both knees.
Regional distribution of cardiac output in young lambs: effect of cold exposure and treatment with catecholamines

1. Lambs less than 3 days old, exposed to thermoneutral or intensely cold conditions in a respiration chamber, were infused with adrenaline or noradrenaline, 1 or 10 μg/kg.min; and the effects on oxygen consumption, cardiac output and its distribution to skin, skeletal and cardiac muscle, liver, spleen, kidney, gut, brown adipose tissue and brain were determined. Cardiac output was estimated by the Fick and dye dilution methods and the distribution of cardiac output by Sapirstein's method of fractional distribution of indicators.
Efficient control design for single phase grid tie inverter of PV system

In the past decade the utilization of renewable energy is ever increasing due to the scarcity of fossil fuels. The excessive power from renewable energy is considered mandatory in integration that improves the performance of the electric transmission system in terms of better reliability and eco green power generation. Extraction of abundant of power from the solar and interfacing to the electric grid through the power electronic components plays a significant role. However, the operation and control of the electric power system becomes very challenging during the integration. This paper uses single stage high performance maximum power point tracking (MPPT) for solar photovoltaic power generation. An efficient control design of current and voltage controllers is designed and a 3kW single phase grid connected PV inverter is proposed and validated using MATLAB/Simulink/PLECS.
Addressing the attitudes of service providers: increasing access to professional midwifery care in Nepal

Increasing access to professional care during labour and delivery is the central strategy in Nepal's commitment to reducing its maternal mortality ratio. This paper outlines a number of complementary interventions used by the Nepal Safer Motherhood Project to address the negative attitudes prevalent among service providers, which is a contributing factor to the under-utilization of the health-care services. The perspectives of the community and the service providers are presented, with a discussion of the importance of effective communication, the establishment of positive relationships and a demonstration of the critical role of local ownership and involvement in bringing about a positive change.
On Uterine Angiosarcomas: 2 Additional Cases.

To the Editor: We read with great interest the paper titled ‘‘Uterine Angiosarcoma: A Case Report and Literature Review’’ published in the May issue of 2016 (1). We wish to report 2 additional cases of uterine angiosarcoma, including one with cytogenetic studies. A 63-yr-old presented with postmenopausal bleeding. Magnetic resonance imaging showed cystic endometrial degeneration, and an endometrial biopsy contained only benign inactive endometrium. Her past medical history included myomectomies 30 and 2 yr prior. Hysterectomy and bilateral salpingooophorectomy with staging biopsies were performed. On gross examination the uterus weighed 1134 g and measured 18 15 14 cm, with distortion by >10 leiomyomata. There was a 14 7.5 5.0 cm intracavitary polypoid lesion with a fleshy, yellow-tan cut surface (Fig. 1A). A frozen section analysis on the polyp was reported as atypical stroma, cannot rule out carcinosarcoma. The polyp was examined in a total of 25 cassettes. Microscopically the stroma of the polypoid lesion showed a poorly differentiated malignant spindled cell proliferation, that in areas showed focal slit-like spaces, and anastomosing irregular vascular spaces lined by atypical cells (Fig. 1B). The tumor invaded 50% of the myometrium; tumor necrosis was <5%. The mitotic rate was 19/10 high-power fields. The background polyp was a benign endometrial polyp without evidence of adenosarcoma or adenocarcinoma. The cervix, tubes and ovaries, lymph nodes, and omentum were benign. The following immunohistochemical stains were positive: vimentin, CD31, CD34, D2-40, p16, ETS transcription regulator, cMYC, and BCL-1. The following stains were negative: CD10, CD117, desmin, pancytokeratin (AE1/AE3), epithelial membrane antigen, estrogen receptor, progesterone receptor, S-100, HMB45, chromogranin, synaptophysin, and CD56. Reticulin stain showed cords and groups of cells surrounded by reticulin fibers. Karyotyping revealed 46,X,t(X;12)(p22.1;q15)[5]/46,XX[15], that is a clone with X;12 translocation. The patient was treated with docetaxel and is disease-free at 1-yr follow-up. The second patient presented at 61 yr of age with postmenopausal bleeding and underwent hysterectomy with bilateral salpingo-oophorectomy and bilateral pelvic node sampling. On gross examination, the uterus weighed 2034g and measured 19.5 16 15 cm, and was distorted by numerous leiomyomata. There was a 15 cm dark-brown necrotic mass with a homogenous appearance involving the endometrial cavity but also extending to over 50% of the myometrial thickness (2.4 cm). Frozen section showed a high-grade malignant spindle cell neoplasm. Histologically, the lesion was composed of short spindle to oval
Stellungnahme zum ersten Fortschrittsbericht der Bundesregierung für das Berichtsjahr 2013: Expertenkommission zum Monitoring-Prozess "Energie der Zukunft"

Das vorliegende Dokument ist die Stellungnahme zum zweiten Monitoring-Bericht der Bundesregierung zur Energiewende. Zur Begleitung des Monitoring-Prozesses "Energie der Zukunft" wurde von der Bundesregierung eine Kommission aus unabhangigen Energieexperten berufen. Die Expertenkommission erstellt in jedem Jahr eine Stellungnahme zum Entwurf des Monitoring-Berichts. Bei der Stellungnahme der Expertenkommission geht es um die wissenschaftliche Einordnung und Bewertung der Monitoring-Berichte der Bundesregierung. Am 8. April 2014 wurde der zweite Monitoring-Bericht "Energie der Zukunft" von der Bundesregierung veroffentlicht. Anhand von Indikatoren wird im Bericht das Fortschreiten der Energiewende abgebildet. Er wurde vom Bundeswirtschaftsministerium unter Beteiligung der anderen Ressorts und nachgeordneter Behorden erarbeitet.
A secondary control based on fuzzy logic to frequency and voltage adjustments in islanded microgrids scenarios

This paper aims to propose a secondary control algorithm based on Fuzzy Logic to adjust frequency and voltage in islanded microgrids. It is well-known, that, when a microgrid changes its operation from grid-connected to islanded mode, the time domain variability of the loads will change the frequency and voltage profiles of the system. In this sense, the operation of the system might become unsafe and out of the acceptable ranges of quality. It is essential that the MGCC be able to restore the frequency and voltage through the secondary control. In this context, a Fuzzy approach is proposed to change the frequency and the voltage reference values in the droop equation of the Voltage Sources Inverters to correct them. The main idea of this paper is to consider these variables uncoupled and then correct each one separately, taking into account that the frequency is global and the voltage is local variables of the system. As results of this work, this paper brings the frequency and voltage profiles of a modified IEEE Feeder Test during a random day, showing the behavior of theses variables with and without the proposed algorithm.
Biopatterned CTLA4/Fc Matrices Facilitate Local Immunomodulation, Engraftment, and Glucose Homeostasis After Pancreatic Islet Transplantation

Pancreatic islet transplantation (PIT) represents a potential therapy to circumvent the need for exogenous insulin in type 1 diabetes. However, PIT remains limited by lack of donor islets and the need for long-term multidrug immunosuppression to prevent alloimmune islet rejection. Our goal was to evaluate a local immunoregulatory strategy that sustains islet allograft survival and restores glucose homeostasis in the absence of systemic immunosuppression. Nanogram quantities of murine CTLA4/Fc fusion protein were controllably delivered within human acellular dermal matrix scaffolds using an inkjet-based biopatterning technology and cotransplanted with allogeneic islets under the renal capsule to create an immunoregulatory microenvironment around the islet allograft. We achieved long-term engraftment of small loads of allogeneic islet cells with 40% of MHC-mismatched mouse recipients maintaining sustained normoglycemia following pancreatic β-cell ablation by streptozotocin. Biopatterned CTLA4/Fc local therapy was associated with expansion of Foxp3+ regulatory T cells and shifts in cytokine production and gene expression from proinflammatory to regulatory profiles, thus substantially benefiting islet allografts survival and function. This study is a new paradigm for targeted therapies in PIT that demonstrates the favorable effects of immune alterations in the transplant milieu and suggests a unique strategy for minimizing systemic immunosuppression and promoting islet allograft survival.
Safety, speed, and style: interaction design of an in-vehicle user interface

Constrained by tight schedule and driven by both safety-critical and aesthetic concerns, an interdisciplinary team designed a novel in-vehicle multimodal, multimedia interface by an unconventional, streamlined process. The distinctive interface architecture and interaction design emphasize style and simplified interaction through strong visual design to speed user recognition, interpretation, and task completion, reducing driver distraction and cognitive load.
Hbo1 Links p53-Dependent Stress Signaling to DNA Replication Licensing

ABSTRACT Hbo1 is a histone acetyltransferase (HAT) that is required for global histone H4 acetylation, steroid-dependent transcription, and chromatin loading of MCM2-7 during DNA replication licensing. It is the catalytic subunit of protein complexes that include ING and JADE proteins, growth regulatory factors and candidate tumor suppressors. These complexes are thought to act via tumor suppressor p53, but the molecular mechanisms and links between stress signaling and chromatin, are currently unknown. Here, we show that p53 physically interacts with Hbo1 and negatively regulates its HAT activity in vitro and in cells. Two physiological stresses that stabilize p53, hyperosmotic shock and DNA replication fork arrest, also inhibit Hbo1 HAT activity in a p53-dependent manner. Hyperosmotic stress during G1 phase specifically inhibits the loading of the MCM2-7 complex, providing an example of the chromatin output of this pathway. These results reveal a direct regulatory connection between p53-responsive stress signaling and Hbo1-dependent chromatin pathways.
Migrating personality theories Part 2: towards a theory of the balanced personality?

Some personality schemas are seen to compete with others, but might they are really be complimentary? Two trait approaches, MBTI and Mindscape theory, are normally considered to be competitive, and we shall show that their migrated forms into knowledge cybernetics can illustrate complementarity. This paper was the Highly Commended Award Winner at the Literati Network Awards for Excellence 2010.
The effect of fertility control on the transmission of bovine tuberculosis in wild brushtail possums

Abstract AIM: To determine the effect of fertility control on the rate of transmission of bovine tuberculosis (Tb), caused by Mycobacterium bovis, in brushtail possums (Trichosurus vulpecula). METHODS: At two study sites with a history of Tb infection in the resident possum population, a sample of adult male and female possums (n=50), determined by palpation to be Tb-free, was surgically sterilised by gonadectomy. A sample of untreated Tb-free male and female possums (n=54) served as controls. Each study site was trapped every 2 months over a 3-year period, and the Tb status of the individuals in the trial assessed. At the conclusion of the trial, all remaining experimental individuals were killed, necropsied and examined for characteristic lesions typical of Tb. The rate of transmission of Tb infection was estimated using the incidence of tuberculous cases in the experimental animals and comparing it between sites, sex and sterilisation treatment. RESULTS: Sterilisation by gonadectomy resulted in a reduction in the rate of transmission of Tb in male possums by 53%, but a corresponding increase in sterilised females for reasons that are still unclear. However, this interaction was statistically weak (p=0.10). When the sexes were combined, there was no overall effect of sterilisation on the rate of transmission of Tb (p=0.43). Sterility treatment notwithstanding, there was a highly significant difference in the rate of transmission between the sexes (p=0.01), being almost one order of magnitude higher in untreated males compared with untreated females. CONCLUSIONS: Although lacking strong statistical support, these results suggest that fertility control that targets endocrine control of fertility may provide some additional benefits for disease control over that achieved by reductions in population density, by reducing the rate of transmission of M. bovis in male possums. However, additional studies are needed to confirm the validity of these results. The large difference in the rate of transmission of M. bovis in untreated males compared with untreated females suggests that transmission of Tb among males may be an important driver of the dynamics of Tb infection in possums.
Warning labels formulated as questions positively influence smoking-related risk perception

Research on warning labels printed on cigarette packages has shown that fear inducing health warnings might provoke defensive responses. This study investigated whether reformulating statements into questions could avoid defensive reactions. Smokers were presented with either warning labels formulated as questions, textual warning labels, graphic warning labels, or no warning labels. Participants’ smoking-related risk perception was higher after exposure to warning labels formulated as questions or no warning labels than after exposure to textual or graphic warning labels. These results indicate that reformulating statements into questions can avoid defensive responses elicited by textual- and graphic warning labels.
Strategies for Optimizing Antiepileptic Drug Therapy in Elderly People

The elderly take more antiepileptic drugs (AEDs) than all other adults. This extensive use directly correlates with an increased prevalence of epilepsy in a growing population of older people, as well as other neuropsychiatric conditions such as neuropathic pain and behavioral disorders associated with dementia and for which AEDs are administered. The agents account for nearly 10% of all adverse drug reactions in the elderly and are the fourth leading cause of adverse drug reactions in nursing home residents. Numerous factors associated with advanced age contribute to the high frequency of untoward drug effects in this population; however, strategies are available to ensure optimal outcomes.
Miniaturizable Si-based light intensity Modulator for integrated sensing applications

A Si-based light modulator working in the near infrared at frequencies up to 300 kHz is proposed. The device proposed is a bipolar mode field effect transistor (BMFET) integrated in an Si rib waveguide. The operation principle is the light dispersion/absorption by a plasma of free carriers that can be moved in or out of the optical path. It works as a pure amplitude light modulator; hence, it can be shrunk. Its small dimensions, only 100 mum in length and less than 50 mum in width in the proposed version, make it suitable for monolithic integration for applications where the major constraints are the device dimensions. As an example, the device application to an integrated gas sensing or chemical absorption spectroscopy system is also described
Developing the Measurement Scale of Information Quality for Social Q&A Sites

Social Q&A sites take advantage of the wisdom of crowds and produce huge number of answers every day. This research-in-progress paper aims to develop a measurement scale of Information Quality (IQ) for social Q&A from the perspective of the user perception. Based on the previous studies with a set of attributes, a conceptual framework of IQ in social Q&A context is developed. Five scholars in the IS field are also interviewed for helping us modify this scale. Baidu Knows, which is the most influential Chinese social Q&A website, is used to conduct the empirical study. This paper employs the Exploratory Factor Analysis (EFA) to test our preliminary measurement scale and make some further revisions. The findings show the IQ of social Q&A includes four dimensions, i.e., Content Quality, Source Quality, Performance Quality, and Emotion Quality with a total of 19 key indicators. This tentative study of IQ evaluation is effective in identifying high-quality answers on social Q&A sites. Moreover, it also has the potential to contribute to the interaction design of social Q&A sites.