Miracle-dz/UniFAR-FTUs huggingface dataset:
Short latency somatosensory evoked potentials in brain-dead patients using restricted low cut filter setting.

This paper describes the SSEP patterns in BD when using restricted filter bandpass setting, with special emphasis on the dissociation of some SSEP components when cephalic and non-cephalic references are used. A characteristic SSEP pattern was found: absence of N20 and later responses in the Cc'-Fpz lead and preservation of all or some of the so-called subcortical components in the rest of the derivations. We noted an interesting dissociation in which some SSEP components were not recorded in the scalp-non cephalic derivations, but they were still present in the neck-cephalic and spine channels, with inverse polarity. We selected a restricted bandpass for the scalp-non cephalic, the neck-cephalic and the spine derivations, and we found this dissociation not only for P13-N13 and P14-N14, but for Nm-Pm' and Pm-Nm' components. It is likely that components Nm-Pm' and Pm-Nm' are "far-field potentials" that appear when the slow wave N18 is filtered out by the use of a restricted low filter setting. Our data further suggest that all components after N14-P14, recorded with restricted filter bandpass also recognize two distinct generator sources. Rostral generators are located probably in the brainstem and/or thalamus, but at least a significant part of these SSEP components are generated at the very lower part of the medulla oblongata (dorsal column nuclei) and/or at the upper cervical spine. (ABSTRACT TRUNCATED AT 250 WORDS)
Transcriptional Regulation of Mammalian Genes in Vivo

The past two decades have brought a major evolution in our understanding of promoter structure, transcription factors, and mechanisms by which transcriptional initiation is regulated in eukaryotes. Multiple approaches have been used to establish current models for transcriptional regulation, including the development of in vitro transcription systems using either naked DNA or reconstituted chromatin, genetic analysis of gene regulation in yeast and Drosophila, and in vivo analysis of either endogenous cellular genes or transiently transfected, exogenous gene promoters. It is now clear that chromatin structure, once considered to be transparent to the process of transcription, plays an important role in the regulation of gene expression (reviewed in Ref. 1). Since all cellular genes are packaged into ordered chromatin structures, an understanding of the mechanisms by which nucleoprotein structure influences transcription activation is necessary for a complete paradigm of gene regulation in higher eukaryotes. Studies on regulation of endogenous mammalian genes are challenging due to the lack of genetic techniques available in yeast and Drosophila systems, which allow targeted insertion of promoters and gene disruption. Structural analysis of integrated gene promoters in mammalian cells requires the time-consuming generation of multiple stable cell lines or pools, in which the integrated genes would be subject to position effects from surrounding chromatin. Therefore, the identification and characterization of factors involved in mammalian gene expression have been addressed primarily through the use of transient transfection assays. In this approach, exogenous plasmid DNA, usually promoter/reporter constructs and transcription factor expression vectors, is introduced into cultured cells and expressed transiently, without replication or integration into the cellular genome. A variety of transfection methods has been utilized, including calcium phosphate precipitation (2), DEAE-dextran (3), electroporation (4, 5), and liposomemediated transfer (6). These studies have resulted in an abundance of information about promoter structure (i.e. identification of cisacting elements), transcription factor structure and function, and the characterization of transcription factor interactions that are part of various cellular regulatory pathways. However, in light of the accumulating evidence indicating a role for chromatin structure in transcription, it is appropriate to question whether transiently transfected gene promoters are adequate models for transcriptional regulatory mechanisms active on endogenous genes in ordered, replicated chromatin.
Understanding the relationship between duration of untreated psychosis and outcomes: A statistical perspective

Although the relationships between duration of untreated psychosis (DUP) and outcomes are often assumed to be linear, few studies have explored the functional form of these relationships. The aim of this study is to demonstrate the potential of recent advances in curve fitting approaches (splines) to explore the form of the relationship between DUP and global assessment of functioning (GAF).
PROFILING IN BASKETBALL: PHYSICAL AND PHYSIOLOGICAL CHARACTERISTICS OF ELITE PLAYERS

The purpose of this study was to describe structural and functional characteristics of elite Serbian basketball players and to evaluate whether players in different positional roles have different physical and physiological profiles. Five men's basketball teams participated in the study and competed in the professional First National League. Physiological measurements were taken of 60 players during the final week of their preparatory training for competition. According to positional roles, players were categorized as guards (n = 20), forwards (n = 20), and centers (n = 20). Guards were older (p < 0.01) and more experienced (p < 0.01) as compared with both forwards and centers. Centers were taller and heavier than guards and forwards (p < 0.01), whereas forwards had significantly higher height and weight than guards (p < 0.01). Centers had more body fat (p < 0.01) as compared with forwards and guards. Also, centers had significantly lower estimated &OV0312;O2max values (p < 0.01) compared with forwards and guards. In addition, the highest heart rate frequencies during the last minute of the shuttle run test were lower in guards (p < 0.01) as compared with forwards and centers. Vertical jump power was significantly higher in centers (p < 0.01) as compared with guards. The results of the present study demonstrate that a strong relationship exists between body composition, aerobic fitness, anaerobic power, and positional roles in elite basketball.
Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression.

The sorting-out of embryonic cells from a cell mixture and the selective spreading of one cell population over the surface of another have been attributed to various causes. These include differentials in chemotaxis, in cellular adhesiveness, in cell surface contractility, in speed of cell movement, and in the timing of postulated changes in cellular adhesive and motile properties. One of us earlier predicted on mathematical grounds that two motile cell types differing only in the level of expression of a single cell adhesion system should not only segregate from one another but also arrange themselves with the less cohesive cells enveloping a core of the more cohesive ones. To test these predictions, we combined two populations of L cells transfected with P-cadherin cDNA and expressing this homophilic adhesion molecule in substantially differing amounts. When the two cell populations were intermixed, they segregated to approach a sphere-within-a-sphere configuration, the cell population expressing more P-cadherin forming islands which fused to become an internal "medulla. " When the two cell populations were first formed into separate aggregates which were subsequently allowed to fuse, the cell population expressing more P-cadherin was enveloped by its partner, which formed an external "cortex. " These observations confirm the early prediction and support the conclusion that both morphogenetic movements and the specific anatomical configurations to which they lead can be determined by particular sets of intercellular adhesive intensities, regardless of how these are generated and in the absence of differentials in other parameters.
State Parties: Independent Partners The Money Relationship

This study examines the money flow relationship between the state parties and their national partners. What impact does money coming from the national parties have on the organization and operation of state parties? This research examines state finance reports from political parties in 15 states compared to their reports to the FEC in 1996 and 1998. This time period covers both presidential and gubernatorial election cycles in the 15 states and 30 state parties. The research answers several questions:1) State parties raise, on average between 70 percent to 82 percent of all federal (hard) money raised for their state and 2) 40 percent to 60 percent of all non-federal (soft) money raised as well. 3) They contribute, on average, nearly half of all party money raised within their borders in a presidential election year and 90 percent of all money in mid-term election years. In view of this evidence, it is clear that state parties are not dependent upon the national parties but have maintained their autonomy as they become more professionalized and "parties in service. "
PENGARUH CORPORATE GORVERNANCE PRECEPTION INDEX (CGPI), STRUKTUR KEPEMILIKAN, DAN UKURAN PERUSAHAAN TERHADAP KINERJA KEUANGAN

This study aimed to examine the influence of Corporate Gorvernance Perception Index (CGPI) , ownership structure , and firm size on financial performance. CGPI is the result of the assessment and ranking of the application of corporate governance in companies listed on the Indonesia Stock Exchange (IDX) conducted by the Indonesian Institute for Corporate Governance (IICG). The population in this study are listed Company on Corporate Gorvernance Preception Index (CGPI) 2010-2012 . By using purposive sampling obtained a sample of 60 companies . The data analysis technique used is Ordinary Least Square regression (OLS) . The results showed that the variables of Corporate Gorvernance Perception Index (CGPI) and managerial ownership effect significant positive on the company's financial performance. Meanwhile, institutional ownership and firm size is not effect significant positive on financial performance. Keywords: good corporate gorvernance, ownership structure, company size and return on equity.
Cargo navigation across 3D microtubule intersections

Significance Eukaryotic cells use microtubule (MT)-based transport to control the distribution of cargos across their complex and crowded environment. Prior models of MT-based motility considered cargo behavior on single filaments or simple networks. However, numerous recent reports revealed surprisingly complex 3D MT networks and associated complex cargo motility in cells. Such phenomena could not be modeled in previous studies. We show (via a recently developed experimental approach and in silico modeling) that network geometry plays a significant role in MT-based motility: The 3D properties of a single intersection can determine cargo routing, depending on cargo properties (e.g., size), opening the possibility that tuning 3D network geometry allows for selective targeting of cargos around the cell. The eukaryotic cell’s microtubule cytoskeleton is a complex 3D filament network. Microtubules cross at a wide variety of separation distances and angles. Prior studies in vivo and in vitro suggest that cargo transport is affected by intersection geometry. However, geometric complexity is not yet widely appreciated as a regulatory factor in its own right, and mechanisms that underlie this mode of regulation are not well understood. We have used our recently reported 3D microtubule manipulation system to build filament crossings de novo in a purified in vitro environment and used them to assay kinesin-1–driven model cargo navigation. We found that 3D microtubule network geometry indeed significantly influences cargo routing, and in particular that it is possible to bias a cargo to pass or switch just by changing either filament spacing or angle. Furthermore, we captured our experimental results in a model which accounts for full 3D geometry, stochastic motion of the cargo and associated motors, as well as motor force production and force-dependent behavior. We used a combination of experimental and theoretical analysis to establish the detailed mechanisms underlying cargo navigation at microtubule crossings.
Data Hiding Using Fibonacci EDGE Based Steganography for Cloud Data

Cloud Computing is a powerful, flexible, cost efficient platform for providing consumer IT services over the Internet. However Cloud Computing has various levels of risk factors because most important information is outsourced by third party vendors, which means harder to maintain the level of security for data. Steganography is art of hiding information in an image. In this most of the techniques are based on the Least Significant Bit(LSB) bit ,but the hackers easily detect as it embed data sequentially in all pixels . Instead of embedding data sequentially some of the techniques choose randomly. A better approach for this chooses edge pixels for embedding data. So we propose novel technique to hide the data in the Fibonacci edge pixels of an image by extending previous edge based algorithms. This algorithm hides the data in the Fibonacci edge pixels of an image and thus ensures better security against attackers.
Effect of 2,4,6‐trinitrobenzenesulphonic acid (TNBS)‐induced ileitis on the motor function of non‐inflamed rat gastric fundus

During intestinal inflammation, motility disturbances are not restricted to inflamed regions, but may also occur in remote non‐inflamed sites of the gastrointestinal tract. Our aim was to investigate the motor function of the gastric fundus after the induction of terminal ileitis in the rat. Ileal inflammation was induced by intraluminal installation of 2,4,6‐trinitrobenzenesulphonic acid (TNBS) into the ileum. Inflammation was assessed both histologically and biochemically. Contractions and relaxations of longitudinal muscle strips from the gastric fundus were studied 36 h and 1 week later. During the acute phase of ileal inflammation (36 h), the non‐inflamed stomach was distended. The contractility of longitudinal muscle strips of the gastric fundus was decreased due to a post‐receptor defect. In addition, nonadrenergic noncholinergic (NANC) relaxations were inhibited due to neuronal dysfunction. Aortic contractility remained normal and the mere presence of food in the stomach did not account for the disturbed neuromuscular function in the gastric fundus. Ablation of extrinsic primary afferent neurones by capsaicin further impaired gastric fundus contractility. Transection and re‐anastomosis of the jejunum reversed the effect of TNBS‐induced ileitis on the neuromuscular function of the gastric fundus. One week after TNBS, cholinergic neurotransmission was increased in the gastric fundus. During acute ileitis, smooth muscle cell contractility and inhibitory NANC neurotransmission are inhibited in the non‐inflamed gastric fundus. This phenomenon may be mediated by intrinsic connections within the enteric nervous system.
The Diminutive in Modern Standard Arabic: An Optimality Theoretical Analysis

The diminutive in Arabic has not received the attention it deserves in the literature. Most of the work done on Arabic morphology has viewed the derivation of Arabic diminutive as a simple process which maps root consonants, according to certain principles, onto well-defined positions of a diminutive pattern. In this paper, I will demonstrate that there is no need to refer to roots in the process of diminutive formation in Arabic. I will also show that under such a view a unified and comprehensive treatment of the diminutive is possible within the framework of Optimality Theory, as developed in Prince and Smolensky (1993). Following Benua (1997) and Ussishkin (1999), the analysis I argue for allows for a correspondence relation between the diminutive forms and the bases from which they are derived. However, my analysis goes beyond that presented in Benua (1997) and Ussishkin (1999) in that it assumes a similar correspondence relation between the diminutive forms and the input. Key words : Optimality theory; Diminutive; Root; Base; Constraint Resume Le diminutif d’Arabe n’a pas recu l’attention qu’elle merite dans la litterature. La plupart du travail effectue sur la morphologie arabe a vu la derivation de l’arabe comme diminutif d’un processus simple qui associe consonnes radicales, selon certains principes, sur des positions bien definies d’un modele diminutif. Dans cet article, je vais le demontrer qu’il n’y a pas besoin de se referer aux racines dans le processus de formation diminutif en arabe. Je vais aussi montrer que, sous ce point de vue d'un traitement unifi e et complet du diminutif est possible dans le cadre de la theorie de l’optimalite, telle que developpee dans Prince et Smolensky (1993). Apres Benua (1997) et Ussishkin (1999), l’analyse que je plaider en faveur d’une relation permet de correspondance entre les formes minuscules et des bases a partir desquelles elles sont derivees. Cependant, mon analyse va au-dela qui sont presentees dans Benua (1997) et Ussishkin (1999) en ce qu’il suppose une relation de correspondance similaire entre les formes minuscules et l’entree. Mots cles : Theorie de l’optimalite; Diminutif; Racine; Base; Contrainte
Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast

In yeast, sphingoid base synthesis is required for the internalization step of endocytosis and organization of the actin cytoskeleton. We show that overexpression of either one of the two kinases Pkh1p or Pkh2p, that are homologous to mammalian 3‐phosphoinositide‐dependent kinase‐1 (PDK1), can specifically suppress the sphingoid base synthesis requirement for endocytosis. Pkh1p and Pkh2p have an overlapping function because only a mutant with impaired function of both kinases is defective for endocytosis. Pkh1/2p kinases are activated in vitro by nanomolar concentrations of sphingoid base. These results suggest that Pkh1/2p kinases are part of a sphingoid base‐mediated signaling pathway that is required for the internalization step of endocytosis. The Pkc1p kinase that is phosphorylated by Pkh1/2p kinases and plays a role in endocytosis was identified as one of the downstream effectors of this signaling cascade.
Internet Adoption by Australian Wineries: Perceived Benefits and Direct Marketing Practices

This article reports on research that examined internet adoption by 225 Australian wineries. Findings indicate that this new technology has been widely embraced by the industry and that numerous perceived benefits, especially associated with e‐mail marketing, are being achieved. The study found that many wineries collected e‐mail addresses for marketing purposes, whilst many engage in a high degree of direct marketing using the e‐mail medium to distribute newsletters. Smaller wineries appear to be the main proponents in using the Internet, the study concluding that this group achieved the highest proportion of Web sales. A link was established between small wineries that had a high use of e‐mail permission marketing and increased web sales.
The ponderous evolution of corporate environmental reporting in Ireland. Recent evidence from publicly listed companies

Ireland's recent rapid economic growth has exacerbated pressure on the environment, leading to increased scrutiny of corporate environmental impacts. In order to assess whether external corporate environmental reporting (CER) has evolved in conjunction with this increased scrutiny, this paper reports on the results of a comprehensive analysis of CER practice among all Irish listed companies. The findings are interpreted using the lens of legitimacy theory. The results indicate that, apart from companies whose core activities have an easily observable environmental impact, there is little extensive CER undertaken, in terms of either its quantity or quality. Despite evidence of increasing trends in disclosure, in most instances disclosing companies remain at the very early stages in their consideration of CER. It is argued that this negligible disclosure potentially represents a minimalistic response to pressure from stakeholders whose power to threaten organizations' legitimacy is limited. Copyright © 2003 John Wiley & Sons, Ltd. and ERP Environment
Supplier relationship management in the construction industry: the effects of trust and dependence

Purpose – There is conflicting evidence of the extent to which business relationships in the UK construction industry are based on trust between closely collaborating parties or alternatively are more adversarial in nature, based on dependence between the parties. This study seeks to provide empirical evidence about the effects of trust and dependence in business relationships in this industry.Design/methodology/approach – A large quantitative survey was conducted with buying firms, resulting in a total of 636 usable responses from 404 firms to test a model using structural equation modelling. The authors test the extent to which trust and dependence act as antecedents to four dimensions identified from the literature as being important determinants of relationship quality: commitment, communication, satisfaction, and long‐term orientation.Findings – The results provide good evidence for the hypotheses in the authors' model: relational characteristics associated with relationship quality are mainly driven.
The Influence Of Market Situation On Diversification Strategy Of Companies Activity

Companies' diversification is analyzed in various aspects. It is generally recognized, that, as adaptation to market strategy, which can be both very successful and very unsuccessful, this phenomenon is controversial. There is a practical and scientific problem to highlight and analyze conditions for successful diversification activity. One of the condition is market situation. The economic crisis has shown that companies which did not assess eventual key changes in market, went to bankrupt, i.e. the ones, which did not provide an alternative for products which are sensitive to shrinking market. It follows, that it is reasonable to examine diversifications dependence on market situation, i.e. to examine influence of developing, shrinking and stable markets to it.