Miracle-dz/UniFAR-FTUs huggingface dataset:
Credit Scoring Using Ensemble of Various Classifiers on Reduced Feature Set

Credit scoring methods are widely used for evaluating loan applications in financial and banking institutions. Credit score identifies if applicant customers belong to good risk applicant group or a bad risk applicant group. These decisions are based on the demographic data of the customers, overall business by the customer with bank, and loan payment history of the loan applicants. The advantages of using credit scoring models include reducing the cost of credit analysis, enabling faster credit decisions and diminishing possible risk. Many statistical and machine learning techniques such as Logistic Regression, Support Vector Machines, Neural Networks and Decision tree algorithms have been used independently and as hybrid credit scoring models. This paper proposes an ensemble based technique combining seven individual models to increase the classification accuracy. Feature selection has also been used for selecting important attributes for classification. Cross classification was conducted using three data partitions. German credit dataset having 1000 instances and 21 attributes is used in the present study. The results of the experiments revealed that the ensemble model yielded a very good accuracy when compared to individual models. In all three different partitions, the ensemble model was able to classify more than 80% of the loan customers as good creditors correctly. Also, for 70:30 partition there was a good impact of feature selection on the accuracy of classifiers. The results were improved for almost all individual models including the ensemble model.
Capturing the Drunk Robber on a Graph

We show that the expected time for a smart "cop" to catch a drunk "robber" on an $n$-vertex graph is at most $n + {\rm o}(n)$. More precisely, let $G$ be a simple, connected, undirected graph with distinguished points $u$ and $v$ among its $n$ vertices. A cop begins at $u$ and a robber at $v$; they move alternately from vertex to adjacent vertex. The robber moves randomly, according to a simple random walk on $G$; the cop sees all and moves as she wishes, with the object of "capturing" the robber---that is, occupying the same vertex---in least expected time. We show that the cop succeeds in expected time no more than $n + {\rm o}(n)$. Since there are graphs in which capture time is at least $n - o(n)$, this is roughly best possible. We note also that no function of the diameter can be a bound on capture time.
Construction of a Conditionally Asporogenous Bacillus thuringiensis Recombinant Strain Overproducing Cry Protein by Deletion of the leuB Gene

One of the common shortcomings with Bacillus thuringiensis (Bt) biopesticides in field application is their instability under UV irradiation. In Bt, the leuB gene encodes the 3-isopropylmalate dehydrogenase. In addition to its role in leucine biosynthesis, LeuB would be likely recruited to catalyze the dehydrogenation of malate in the final step of tricarboxylic acid cycle during sporulation. In this study, we constructed a Bt recombinant strain in which the gene leuB was deleted by using the markerless gene deletion system. The ΔleuB mutant strain showed a conditionally asporogenous phenotype while overproducing insecticidal crystal proteins and retaining its insecticidal activity well in both fermentation and LB media. Furthermore, the metabolic regulation mechanisms of LeuB was elucidated by iTRAQ-based quantitative proteomics approach. Evidences from proteomics data suggested that the inhibited supply of pyruvate (carbon source) was an important factor related to the conditionally asporogenous feature of the mutant. Consistently, the mutant regained its ability to sporulate in LB medium by adding 1% glucose or 1% sodium pyruvate. Taken together, our study demonstrated that deletion of the leuB gene resulted in delayed or completely blocked mother cell lysis, allowing the crystals encapsulated within cells, which makes this recombinant strain a good candidate for developing Bt preparations with better UV-stability.
Bases de Hilbert

This paper describes the contents of Marcelo Hashimoto’s Ma ter dissertation, written under the supervision of Professor J osé Coelho de Pina Jr. This dissertation has the purpose of being an introductory a nd self-contained reference on the concept of Hilbert bases. Such concept was o riginally introduced for a better understanding of the polyhedral structur e of min-max relations in combinatorial optimization. We present an unified a n detailed survey of Hilbert bases that does not depend on their applications i n combinatorics and instead presents some of those applications as simple corol laries of structural and geometric properties. We also estabilish analogies bet we n such properties and classical results on linear algebra, lattice theory and li ear programming. Resumo. Este artigo descreve o conteúdo da dissertação de mestrado 1 de Marcelo Hashimoto 2, escrita sob orientação do Professor José Coelho de Pina Jr. Essa dissertação tem o propósito de ser uma referência in trodutória e autocontida sobre o conceito de bases de Hilbert. Tal conceito fo i riginalmente introduzido para uma melhor compreensão da estrutura polié drica de relações min-max em otimização combinatória. Apresentamos um estud o unificado e detalhado de bases de Hilbert que não depende das suas aplica ções em combinatória e as apresenta como simples corolários de proprie dades estruturais e geométricas. Também estabelecemos analogias entre tais pr opriedades e resultados clássicos em álgebra linear, teoria de reticulados e p rogramação linear.
Resolución de problemas de control estocástico de Mayer mediante ecuaciones en derivadas parciales

En este trabajo proporcionamos condiciones necesarias y suficientes de optimalidad en problemas de control ´optimo estoc´astico de tipo Mayer en tiempo continuo. Nuestro enfoque est´a basado en el principio del m´aximo estoc´astico. Caracterizamos un control ´optimo directamente mediante una ecuaci´on en derivadas parciales, alternativa a la ecuaci´on de Hamilton� Jacobi�Belman, pero que tambi´en permite obtener la funci´on valor de una forma indirecta. Los resultados se ilustran con el an´alisis de un modelo din´amico de un plan de pensiones agregado.
New compact S-band antenna for Nanosatellite TeleMetry and TeleCommand applications - EyeSat program

This paper presents a new compact single-feed circularly polarized S-band antenna for Nanosatellite TT&C applications. The antenna is composed of two crossed dipoles printed on both sides of a substrate, center-fed by a 50Ω coaxial cable. It provides a unidirectional pattern thanks to a reflector placed below the antenna. In order to reduce the size of the structure, this reflector is composed of an Artificial Magnetic Conductor (AMC). The bandwidth of the antenna is 17% (1.98 - 2.35 GHz) and covers the 2.025-2.110GHz TeleCommand band and the 2.2-2.29 GHz TeleMetry band. The size of the entire structure including the radome and the satellite interface is 0. 58λmin of diameter and 0. 081λmin of height where λmin is the wavelength at the lowest frequency. This new antenna concept will be used in the EYESAT CNES Program in 2017.
Improved Sensitivity of Human Immunodeficiency Virus Type 2 Subtype B Plasma Viral Load Assay

ABSTRACT We developed a new assay for human immunodeficiency virus type 2 plasma RNA quantification based on a previous format. The new version performed significantly better than the original regarding the detection of subtype B, allowing the detection of 14 out of 36 plasma RNAs in the subtype B-infected patients not detected with the original version.
Scalable Distributed k-Resilient Name to Address Binding System for Overlays

Many distributed applications build overlays on top of the Internet. Several unsolved issues at the network layer can explain this trend to implement network services such as multicast, mobility and security at the application layer. On one hand, overlays creating basic topologies are usually limited in flexibility and scalability. On the other hand, overlays creating complex topologies require some form of application level addressing, routing and naming mechanisms. Our aim is to design an efficient and robust addressing, routing and naming architecture for these complex overlays. Our only assumption is that they are constrained by the Internet topology. Applications that use our middleware will be relieved from managing their own overlay topologies. Our architecture is based on the separation of the naming and the addressing plans. To implement this property, we have designed a scalable distributed kresilient name to address binding system. This paper describes its design and presents some performance results concerning its scalability, its efficiency and its resilience.
The future of screening, brief intervention and referral to treatment in adolescent primary care: research directions and dissemination challenges

Purpose of review Screening, brief intervention and referral to treatment (SBIRT) offers a practical, integrated model for addressing substance use in primary care settings. This review provides an update of the research on SBIRT for adolescents in primary care, examines current dissemination challenges and suggests future research directions. Recent findings A number of brief screening tools for adolescents have been developed and tested relative to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) substance use disorders. Computerized previsit screening promotes standardization and is a more time-efficient alternative to provider interview. The adolescent brief intervention literature is growing, particularly with respect to technology-based tools, but is still limited, with evidence greatest for alcohol, and for motivational enhancement therapy interventions. Increasing SBIRT implementation in pediatric primary care remains a challenge. Using nonphysician behavioral health providers to deliver SBIRT, and embedding a screener and decision support tool in electronic medical record systems are strategies being investigated to promote SBIRT implementation. Summary Substance use begins in adolescence, and pediatric SBIRT could help to achieve a population-level reduction of substance use-related harms. With a growing number of available tools, adolescent SBIRT effectiveness and feasibility are increasing, but more studies are needed to grow its evidence base, and elucidate strategies to increase implementation.
Making Fat Work

The burgeoning obesity and metabolic disease epidemics in the developed world are exerting a terrible toll on society, yet the precise mechanisms responsible for the emergence of these dramatic trends over a relatively short period of time remain poorly understood. Philip A.Wood's book How Fat Works provides important insights into cellular lipid metabolism, as well as discussing some of the important external contributors to the development of human obesity. The foundation provided by this book allows for the exploration of how body fat has gone from hero during the millennia when starvation was the paramount nutritional risk to its current role as villain in our period of caloric excess. With the incredible personal and societal costs brought about by excess body weight, a comprehensive understanding of the mechanisms responsible for obesity is fundamentally necessary if we are to reverse these dire trends. Here, we delve deeper into some of the forces contributing to the obesity epidemic and discuss some individual measures as well as public policy decisions that may help reverse weight trends, while specifically focusing on the growing problem of pediatric obesity.
Efficient submesh permutations in wormhole-routed meshes

This paper studies how to concurrently permute related logical or physical submeshes in a d-dimensional n/spl times/. /spl times/n physical mesh via wormhole and dimension-ordered routing. Our objective is to minimize the congestion for realizing the permutations, while maximizing the number and dimensionality of permuted submeshes. We show that for d/spl les/2/spl alpha/+/spl beta/, concurrent independent permutations of n/sup /spl beta// related physical submeshes, each of /spl alpha/ dimensions, can be performed in two routing steps without congestion. If the permuted submeshes are logical ones, they can be permuted in one, instead of two, routing step. In addition, any shift operation along any axis of the logical mesh can be performed in the physical mesh without congestion. We also show that if all nodes know the permutation function, any permutation within a submesh of dimensions [2(d-1)/3] can be realized in three routing steps without congestion. <<ETX>>
p38-2, a Novel Mitogen-activated Protein Kinase with Distinct Properties*

Mitogen-activated protein (MAP) kinases are involved in many cellular processes. Here we describe the cloning and characterization of a new MAP kinase, p38-2. p38-2 belongs to the p38 subfamily of MAP kinases and shares with it the TGY phosphorylation motif. The complete p38-2 cDNA was isolated by polymerase chain reaction. It encodes a 364-amino acid protein with 73% identity to p38. Two shorter isoforms missing the phosphorylation motif were identified. Analysis of various tissues demonstrated that p38-2 is differently expressed from p38. Highest expression levels were found in heart and skeletal muscle. Like p38, p38-2 is activated by stress-inducing signals and proinflammatory cytokines. The preferred upstream kinase is MEK6. Although p38-2 and p38 phosphorylate the same substrates, the site specificity of phosphorylation can differ as shown by two-dimensional phosphopeptide analysis of Sap-1a. Additionally, kinetic studies showed that p38-2 appears to be about 180 times more active than p38 on certain substrates such as ATF2. Both kinases are inhibited by a class of pyridinyl imidazoles. p38-2 phosphorylation of ATF2 and Sap-1a but not Elk1 results in increased transcriptional activity of these factors. A sequential kinetic mechanism of p38-2 is suggested by steady state kinetic analysis. In conclusion, p38-2 may be an important component of the stress response required for the homeostasis of a cell.
The effects of electromagnetic fields on B16‐BL6 cells are dependent on their spatial and temporal character

Exposure to low intensity, low frequency electromagnetic fields (EMF) has effects on several biological systems. Spatiotemporal characteristics of these EMFs are critical. The effect of several complex EMF patterns on the proliferation of B16‐BL6 mouse melanoma cells was tested. Exposure to one of these patterns, the Thomas‐EMF, inhibited cell proliferation and promoted calcium uptake. The Thomas‐EMF is coded from a digital‐to‐analog file comprised of 849 points, which provides power to solenoids and can be set to alter timing, intensity, and duration of variable EMF. Setting the point duration to 3 ms generated a time‐varying EMF pattern which began at 25 Hz and slowed to 6 Hz over a 2.5 s repeat. Exposing B16‐BL6 cells to Thomas‐EMF set to 3 ms for 1 h/day inhibited cell proliferation by 40% after 5 days, while setting the point duration to 1, 2, 4, or 5 ms had no effect on cell proliferation. Similarly, exposing cells to Thomas‐EMF set to 3 ms promoted a three‐fold increase in calcium uptake after 1 h, while the other timings had no effect. Exposure to Thomas‐EMF for as short as 15 min/day slowed cell proliferation, but exposure for 1 h/day was optimal. This corresponded to the effect on calcium uptake where uptake was detected after 15 min exposure and was maximal by 1 h of treatment. Studies show that the specific spatiotemporal character of EMF is critical in mediating their biological activities. Bioelectromagnetics. 38:165–174, 2017. © 2016 Wiley Periodicals, Inc.
Bacteraemia and antibiotic use in respiratory syncytial virus infections

Aims: To examine the frequency of and risk factors for bacteraemia in children hospitalised with respiratory syncytial virus (RSV) infection; and to determine current use of antibiotics in hospitalised children with RSV infection. Methods: Retrospective study of all children, aged 0–14 years, admitted to a tertiary children’s hospital with proven RSV infection over a four year period. Children with concurrent bacteraemia and RSV infection were identified, and risk factors examined for bacteraemia. The case notes of a randomly selected comparison sample of 100 of these RSV infected children were examined to assess antibiotic use and population incidence of risk factors for severe RSV infection. Results: A total of 1795 children had proven RSV infection, and blood cultures were sent on 861 (48%). Eleven (0.6%) of the 1795 RSV positive children had bacteraemia. RSV positive children had a significantly higher incidence of bacteraemia if they had nosocomial RSV infection (6.5%), cyanotic congenital heart disease (6.6%), or were admitted to the paediatric intensive care unit (2.9%). Forty five (45%) of the random comparison sample of RSV infected children received antibiotics. Conclusions: Bacteraemia is rare in RSV infection. Children with RSV infection are more likely to be bacteraemic, however, if they have nosocomial RSV infection, cyanotic congenital heart disease, or require intensive care unit admission.
Development of the Brief Bedside Dysphagia Screening Test - Revised: a Cross-Sectional Czech Study.

AIM The purpose of this study was to develop a revised version of the Brief Bedside Dysphagia Screening Test for determining penetration/aspiration risk in patients prone to dysphagia. The priority was to achieve high sensitivity and negative predictive value. METHODS The study screeners conducted bedside assessment of the swallowing function in 157 patients with a neurological (mainly stroke) or an ear, nose, and throat diagnosis (mainly head and neck cancer). The results were compared with a gold standard, flexible endoscopic examination of swallowing. RESULTS For the neurological subgroup (N = 106), eight statistically significant bedside assessment items were combined into the Brief Bedside Dysphagia Screening Test-Revised (BBDST-R). Cut-off score 1 produced the highest sensitivity (95.5%; 95% confidence interval CI [CI]: 84.9-98.7%) and negative predictive value (88.9%; 95% CI 67.2-96.9%). CONCLUSION The BBDST-R is suitable for dysphagia screening in departments caring for patients with neurological conditions.
Infarct size reduction in acute myocardial infarction

### Learning objectives Coronary artery disease is the leading cause of death worldwide, with ST segment elevation myocardial infarction (STEMI) an important contributor. Infarct size following STEMI is a determinant of heart failure and death. This article provides an update on key modalities used to determine infarct size, and recent advances in interventions used to reduce infarct size. The area at risk (AAR) is the region of the myocardial bed supplied by the infarct related artery (IRA). In the era of reperfusion, not all the AAR will become infarcted. Depending on time to reperfusion and the exact location of occlusion, there will be a proportion of the AAR (jeopardised but not infarctedw1) that can be salvaged by reperfusion therapy. This can be calculated as AAR−infarct size (figure 1). Figure 1 Cardiovascular MRI short axis mid cavity slice of a left anterior descending ST segment elevation myocardial infarction (STEMI). The hyperintense area in panel A is the area at risk. The hyperintense area in panel B is the infarct size. The difference between these two areas is the myocardial salvage. The cause of irreversible myocardial damage in STEMI can be divided into two categories: myocardial damage as a result of the myocardial ischaemic process itself; and myocardial damage as a result of reperfusion, termed reperfusion injury. It is difficult to separate out these two components (figure 2). Figure 2 An illustration exhibiting the interaction of the effects on infarct size from time to reperfusion and reperfusion injury (RI) on infarct size. AAR, area at risk; MI, myocardial infarction. Reproduced with permission from Frőhlich et al . w6 ### Ischaemic cascade Following a coronary occlusion, the myocardial bed supplied …
Acoustique modale et stabilité linéaire par une méthode numérique avancée : Cas d'un conduit traité acoustiquement en présence d'un écoulement

Ce travail de these s’inscrit dans l’effort de reduction des nuisances sonores dues a la soufflante d’unreacteur double-flux a l’aide de materiaux absorbants acoustiques, appeles communement «liners». Afind’optimiser ces traitements acoustiques, il convient d’etudier en detail la physique de la propagationacoustique en presence de liner. De plus, il s’agit d’ameliorer la comprehension des instabilites hydrodynamiquespouvant se developper sur un liner sous des conditions particulieres et possiblement generatricesde bruit. Ce travail de these a consiste a developper un code de calcul en formulation Galerkin discontinuepour l’analyse modale et la stabilite dans un conduit traite acoustiquement, code qui a ete applique a desconfigurations realistes, en considerant une section transverse ou longitudinale d’un conduit. Les etudesmodales realisees dans la section transverse ont apporte des informations sur la propagation acoustiquedans une nacelle de turbofan avec des discontinuites du traitement acoustique («splices»), ainsi que dansle banc B2A de l’ONERA. Les calculs dans la section longitudinale ont necessite l’implantation de conditionsaux limites PML pour tronquer le domaine de calcul, ainsi que d’une condition aux limites sur leliner, modelisee en domaine temporel a partir d’une extension de travaux existants dans la litterature.Avec ces outils, le code a permis de mettre en evidence une dynamique de type amplificateur de bruit dueau developpement d’une instabilite hydrodynamique sur le liner en presence d’ecoulement cisaille ainsiqu’un rayonnement acoustique en amont et en aval du conduit du a cette instabilite.
Eu Sei o que Vocês Fizeram (Agora e) na Aula Passada: o TSTView no Acompanhamento de Exercícios de Programação

Em aulas praticas de programacao introdutoria, o professor precisa ter uma visao global do desempenho e do andamento da turma nas atividades planejadas sem perder a visao individual do progresso e das dificuldades de cada estudante. Neste artigo apresentamos nossa experiencia com um ferramental que desenvolvemos para viabilizar o continuo monitoramento das atividades dos estudantes em laboratorio. Nossas primeiras experiencias demonstram que o ferramental torna possivel detectar com mais facilidade as dificuldades individuais dos alunos, e os problemas nas atividades planejadas para a aula. Assim, tem nos permitido atuar de forma mais precisa e agil na solucao de problemas de ensino e aprendizagem.
Prosodie-discours : une interface à multiples facettes

Resume Je propose de conduire une reflexion globale sur les recherches pluridisciplinaires menees actuellement a l’interface de la prosodie et du discours. Pour ce faire, je montrerai quel type de dialogue a pu s’amorcer entre les communautes scientifiques au cours de ces dernieres annees autour de thematiques plurielles concernant a la fois la dimension structurelle, semantico-pragmatique et intersubjective du message parle. Une science etant cumulative par essence, je presenterai ensuite certains soubassements epistemologiques fondamentaux pour les recherches actuelles ; j’insisterai sur l’apport marquant de quelques figures pionnieres qui ont su, dans un contexte linguistique de frilosite generale au regard du discours et de la prosodie, ouvrir des pistes de reflexion qui impregnent les travaux d’aujourd’hui. Pour finir, j’entamerai une discussion critique sur les differents angles d’attaque envisages pour apprehender les relations entre discours et prosodie, les methodes et les points de vue que l’on peut observer, et par dela les specificites des uns et des autres ou les axes de convergence, les points qui restent problematiques parce que contradictoires ou demandant des mises a plat terminologiques, methodologiques et conceptuelles.