Miracle-dz/UniFAR-FTUs huggingface dataset:
Factors Associated With Avoidance of Severe Complications After 25 Yr of IDDM: Pittsburgh Epidemiology of Diabetes Complications Study I

To identify characteristics associated with long-term avoidance of insulin-dependent diabetes mellitus (IDDM) complications, subjects taking part in an epidemiologic natural history study of childhood-onset IDDM, with a duration of disease ≥25 yr, were studied. Nineteen percent of 175 subjects had avoided overt nephropathy, definite cardiovascular and peripheral vascular disease, clinical neuropathy, and proliferative retinopathy. Approximately half of the nonrenal complications occurred in the absence of renal disease. Subjects free of these advanced complications were characterized by a longer duration of disease (P < 0.05), better lipid profile and blood pressure (P < 0.01), and considerably lower glycosylated hemoglobin levels (P < 0.001). Health-related behaviors, including recent medical contact, regular glucose monitoring, physical activity in youth, and avoidance of cigarette smoking, did not relate to complication status, although regular (at least weekly) alcohol consumption was more prevalent (P < 0.05) in those without complications. We conclude that a lower mean glycosylated hemoglobin level is strongly related to the avoidance of all IDDM complications.
ARP Enhancement to Stateful Protocol by Registering ARP Request

Networking has become an essential factor in daily life and activities where the major problem in network security is the safety of the transfer information. The infrastructure for the networking is the TCP/IP suite, and the address resolution protocol is the core part of the standard which maps the logical address into a physical address. Address resolution protocol is defined as a stateless protocol in the network standard. Cache poisoning attacks target the address resolution protocol mapping to redirect the network traffic to the attacker machine, while the spoofing attack is an initialization phase for other attacks such as man-in-the-middle and denial of service attacks. The proposal in this paper is to defeat cache poisoning attacks by discarding the unregister reply, in other words, to enhance the address resolution protocol to become a stateful protocol and send a request based on the number of fake attacker replies received. The suggested address resolution protocol enhancement is examined and implemented in Linux kernel.
Complémentarité dans les Réseaux Sociaux Complémentarité de personnes partageant des propriétés dans les Réseaux Sociaux

Nos travaux precedents portaient sur la detection unifiee de communautes dans les reseaux de per-sonnes representes sous la forme de graphes generalement bipartis : reseaux sociaux, communautes d'acteurs, etc. Dans cet article nous tentons de repondre a des problemes de complementarite qui se posent des que l'on souhaite associer des personnes dans le but de remplir au mieux un objectif. Nous definissons donc la notion de complementarite entre les sommets d'un graphe biparti. Nous utilisons pour cela les notions d'entropie et d'information mutuelle. Nous montrons l'utilite d'une telle demarche et l'interet de l'approche par une experi-mentation sur des exemples bien connus.
Analyzing random permutations for cyclic coordinate descent

We consider coordinate descent methods on convex quadratic problems, in which exact line searches are performed at each iteration. (This algorithm is identical to Gauss-Seidel on the equivalent symmetric positive definite linear system.) We describe a class of convex quadratic problems for which the random-permutations version of cyclic coordinate descent (RPCD) outperforms the standard cyclic coordinate descent (CCD) approach, yielding convergence behavior similar to the fully-random variant (RCD). A convergence analysis is developed to explain the empirical observations.
Energy Efficiency Optimization of Task-Parallel Codes on Asymmetric Architectures

We present a family of policies that, integrated within a runtime task scheduler (Nanox), pursue the goal of improving the energy efficiency of task-parallel executions with no intervention from the programmer. The proposed policies tackle the problem by modifying the core operating frequency via DVFS mechanisms, or by enabling/disabling the mapping of tasks to specific cores at selected execution points, depending on the internal status of the scheduler. Experimental results on an asymmetric SoC (Exynos 5422) and for a specific operation (Cholesky factorization) reveal gains up to 29% in terms of energy efficiency and considerable reductions in average power.
Effect of repeated exercise and recovery on heart rate variability in elite trotting horses during high intensity interval training.

REASONS FOR PERFORMING STUDY Interval training is a commonly used training method for trotting horses. In addition, trainers are provided with efficient and inexpensive heart rate monitor devices for the management of training. HYPOTHESIS Since the high frequency (HF) frequency peak (fHF) of heart rate variability (HRV) corresponds to the breathing frequency in combination with stride frequency during trotting, it is hypothesised that modifications of breathing and stride frequencies induced by repeated exercise could be detected from fHF. METHODS RR interval time series of 7 trotting horses were recorded during an interval training session. Interval training was made up of 5 successive 800 m high-velocity trotting runs (H1, H2.H5) separated by 1 min recovery bouts at low speed (R1, R2.R5). Fast Fourier transform (FFT) and Poincaré plot analysis techniques were applied to RR series. RESULTS Repeated exercise had significant effects on HRV components during interval training. Despite constant trotting velocities during high-speed and recovery, repetition induced a decrease in mean RR interval (H1: 295 +/- 19 vs. H5: 283 +/- 15 msec, P<0.05) and in the root mean square of successive differences in RR series (RMSSD; H1: 6.31 +/- 1.28 vs. H5: 5.31 +/- 1.31 msec, P<0.05). Furthermore, high-speed and recovery repetitions induced an increase in fHF (H1: 1.37 +/- 0.35 vs. H5: 1.62 +/- 0.40 Hz and R1: 0.22 +/- 0.02 vs. R4: 0.64 +/- 0.38 Hz, P<0.05). Hence, recovery induced a decrease in the s.d. of the successive RR series (SDRR; R3: 10.5 +/- 3.96 vs. R5: 6.17 +/- 2.65 msecs, P>0.05) and in the long term index of Poincaré plot (SD2; R1: 43.29 +/- 28.90 vs. R5: 18.19 +/- 9.35 msecs, P<0.05). CONCLUSIONS The observed increase in fHF during the interval training could be induced by alterations of the coupling between breathing and stride frequency linked to the emergence of fatigue. The decrease in SD2 and SDRR during successive recovery bouts could be linked with a deterioration of the recovery pattern. POTENTIAL RELEVANCE HRV can provide breathing frequency data of Standardbreds during training without any respiratory device. Furthermore, HRV could provide useful makers of the emergence of fatigue states during training.
When a minor head injury results in enduring symptoms: a prospective investigation of risk factors for postconcussional syndrome after mild traumatic brain injury

Objective A significant proportion (15–30%) of patients with mild traumatic brain injury (MTBI) are at risk of developing postconcussional syndrome (PCS). The aim of this study was to investigate the contributions of cognitive, emotional, behavioural and social factors to the development of PCS and identify early predictors. Methods A prospective cohort design was employed. 126 MTBI patients completed baseline questionnaire assessments within 2 weeks of the injury and 107 completed follow-up questionnaire assessments at 3 and 6 months. A series of self-report measures were used to assess cognitive, behavioural and emotional responses to MTBI. The primary outcome was the ICD-10 diagnosis for PCS. Demographic and clinical characteristic variables were compared between PCS cases and non-cases using independent sample t tests and χ2 tests. Individual and multivariate logistic regression analyses were used to detect predictors of PCS. Results Of 107 MTBI patients, 24 (22%) met the criteria for PCS at 3 months and 22 (21%) at 6 months. Individual logistic regression analysis indicated that negative MTBI perceptions, stress, anxiety, depression and all-or-nothing behaviour were associated with the risk of PCS. Multivariate analysis revealed that all-or-nothing behaviour was the key predictor for the onset of PCS at 3 months while negative MTBI perceptions predicted PCS at 6 months. Conclusions The study provides good support for the proposed cognitive behavioural model. Patients' perceptions of their head injury and their behavioural responses play important roles in the development of PCS, indicating that cognitive and behavioural factors may be potential targets for early preventive interventions.
Power Management for Multiple-Pickup IPT Systems in Materials Handling Applications

Multiple-pickup inductive power transfer (IPT) systems are popular in clean rooms and other materials handling applications. Currently, these systems use power supplies rated at or above the sum of the total pickups' rated power to prevent the system from overloading. In consequence, there is spare capacity that is not always utilized. This paper proposes a novel power management control for each of two popular load regulation methods used in materials handling applications, namely: 1) fast-switching and 2) slow-switching. The approach enables power supplies with smaller capacity to be used, without compromising system integrity and thereby saves system cost. The proposed controls have minimal impacts on the pickups' normal operation during light loading periods and heavy loading periods all pickups are affected equally. In addition, it is possible to modify the controls slightly to assign pickups with different priorities such that the normal operation of critical tasks is guaranteed. The proposed methods use the IPT frequency as the communication channel, removing the need for an extra communication system. They also require minimal adjustments to usual system configurations and can therefore be easily implemented on existing systems. Experimental results show that both proposed controls are valid under various loading conditions.
Development of an allergen extract for sublingual immunotherapy – evaluation of Staloral

Background: Specific immunotherapy (IT) is an effective treatment for rhinitis and asthma caused by aeroallergens sensitization. Sublingual IT (SLIT) was introduced to solve the problem of systemic reactions to subcutaneous IT (SCIT) and developed to represent an actual treatment option. It is now generally accepted that allergen doses much higher than those administered by SCIT must be used to achieve clinical efficacy on allergic symptoms. Objective: To evaluate the characteristics of Staloral, an allergen extract produced by Stallergenes (Antony, France) in terms of practical administration, efficacy, safety and mechanism of action. Methods: Data were obtained from 20 double-blind, placebo-controlled studies using Staloral in patients sensitized to pollens and house-dust mites, and also from open studies concerning practical administration and the mechanism of action. Results/conclusion: Efficacy and safety of Staloral, as demonstrated by the revision of the studies, which used doses up to 1125 times those administered with SCIT, are very satisfactory and confer to this allergen extract optimal characteristics for treating patients with seasonal allergies due to pollens or with perennial symptoms induced by dust mites. The main mechanism of action is the interaction with dendritic cells of the oral mucosa and the subsequent tolerance induced in T cells.
Running responses of Trichinella spiralis-infected CD-1 mice

SUMMARY Male CD-1 mice inoculated by gavage with 400 larvae of Trichinella spiralis exhibited an increased latency of the wall-seeking response as well as a decline in running speed and the distance travelled to the first stop when compared with normal controls or animals inoculated with only 100 larvae. Doses of 200 larvae of this parasite affected running speed and distance travelled but not the advent of the running response. Such changes in behaviour may reduce the competitive fitness of the host and render it more susceptible to predation.
SPORTS RECREATION & FITNESS: AN INVESTIGATION ON NUTRITIONAL EVALUATION IN TERM OF PROTEIN, MINERALS AND FAT EVALUATION AMONG UNDERGRADUATE STUDENTS IN UNITEN

Recent developments in Malaysia have highlighted the fact that the lack of physical activity or sedentary lifestyle will not only contribute to rising obesity rates, but it also directly contributes to the risk of several physical and psychological health, and heart disease still remains one of the nation? s leading causes of death. The purpose of this investigation was to evaluate the effect of a 12-week of physical activities on nutritional evaluation in term of protein, minerals and fat evaluation among undergraduate students in UNITEN. Hundred and eighteen subjects were recruited from Sports and Recreation Management course in semester 2 2012/2013. Subjects were all male both local and foreign students between the ages of 19 and 30 years. Subjects are engineering students who were not enrolled in any exercise program over the period of one year (sedentary). A pre-test-post-test control research design was utilized. Subjects were assigned to a 12-week of physical activities for 50 minutes per session at three times a week (36 sessions). The In Body 720 Body Composition analysis examined nutritional evaluations which include protein, minerals, and fat were used to assess changes in both the nutritional evaluation respectively, as a result of the physical activities at one and 12-weeks. Statistical analysis included (group x time) measures t-test to determine mean differences. Results for nutritional evaluation indicate a significant p =
Wetware: A Computer in Every Living Cell

The continuous repetition of Christian de Duve’s primary thesis in Genetics of Original Sin ensures that however little the reader understands or is interested in biology, he will have no doubt as to the author’s primary concern: Natural selection has made humans poor prognosticators. As evolutionary adaptation is all about living (and reproducing) in the moment, humans have evolved some unfortunate traits and are headed toward a Very Bad End, unless drastic change is implemented. The reader is also certain to realize de Duve’s good news, namely that humans alone can (and must) change their nature. The particulars here, however, are vague and underdeveloped as de Duve loses the clarity and insight he brought to the first three-quarters of the book. Genetics of Original Sin is divided into four parts. “The History of Life on Earth” provides proof of evolution; “The Mechanisms of Life” lays out the rudimentary biology needed to understand de Duve’s main objectives, and in “The Human Adventure,” human evolution, in particular, is described. Finally, “The Challenges of the Future” includes the author’s speculations and suggestions about ways to avert the coming apocalypse. The book draws intriguing parallels to the Christian narrative of evil entering the world through original sin (here played by natural selection) and subsequent redemption (the role of redeemer now played by humankind). De Duve carries this comparison throughout the book and returns again to religion (including the major monotheistic and Eastern traditions) in the final section as a vehicle for changing human nature. The book is careful to distinguish between claims that can be proven by science (evolution) and those that cannot be refuted by science (the existence of God). This crucial distinction prevents de Duve from alienating religious readers. Such readers are important because a primary purpose of the book is to encourage religion as a means to carry the author’s message of human responsibility to the Earth — namely, to reduce the population and curb our more destructive impulses. Overall, the book is a pleasure to read. While the author is certainly no Nathaniel Hawthorne, the prose is pleasantly poetic and the vocabulary extensive, indicative of a well-read individual. The science, as de Duve describes it, remains straightforward and simple, but the ideas he presents and parallels he draws are not, making the book a worthwhile read for biologists as well as politicians and religious leaders. Through the use of careful analogies and clear transitions, de Duve makes biology accessible to virtually any reader. In addition, Genetics of Original Sin often provides a historical context for scientific discovery, describing biological innovation as the work of individuals, thereby heightening the drama of science.
Defect and temperature dependence of tunneling in InGaAs/GaAsSb heterojunctions with varying band alignments

Summary form only given. In this work, we utilize two-terminal measurements of conductance slope as a means to probe the nature of tunneling at the interface without convolution of three-terminal parasitic effects such as gate-oxide traps or parasitic leakage pathways resulting from the more complicated geometry of a three-terminal device. The conductance slope gives an approximation to a transistor response in two terminals. [6,7] By removing three-terminal parasitics, the true nature of tunneling and its dependence on materials defects can be seen. Additionally, it allows for a comparison to be made between tunneling with and without gate-oxide traps present to better determine if such defects could be playing a role in the observed temperature dependence of published devices. In this work, we epitaxially grow InAs/GaSb and InGaAs/GaAsSb of varying alloying compositions and hence, varying band alignments. We study the effect of material defects on conductance slope at different band alignments via the effect of buffer layers to grade the strain. We also examine the temperature dependence of conductance slope to make important insights into the true nature of tunneling at the interface in the absence of oxide traps.
Comment on 'Optimality of the sequential probability ratio test for nonstationary observations' by Y. Liu and S.D. Blostein

For original paper see IEEE Trans. Inform. Theory, vol.38, p.177-82 (1992). Liu and Blostein (1992) consider sequential tests with varying stopping bounds (NSPRT) for testing simple hypotheses on independent but nonstationary observations. They state a considerable generalization of the famous Wald-Wolfowitz theorem [1948] on the (simultaneous) minimization of the expected sample sizes for given error probabilities (Liu and Blostein, Theorem 27). Unfortunately, this statement fails to be true: 1) a simple counterexample may be constructed by choosing densities f/sub 01//spl ne/f/sub 1,1/ such that 0 >
ASSESSING AND QUANTIFYING NETWORK EFFECTS IN AN ONLINE DATING MARKET

Motivat ion. Two-sided markets (or multi-sided markets more generally) are roughly defined as platforms that enable transaction and interaction amongst end-users of different types (Parker and Val Alstyne 2005; Rochet and Tirole 2006). Examples of these markets are now quite prevalent – e.g., Hulu matches video content providers with end-consumers and advertisers, eBay connects buyers and sellers, and AirBNB links renters and hosts. Perhaps the oldest example, however, is the market for dating, which we consider here.
Performance analysis of target acceleration resolution for radar based on ambiguity function

Under the circumstance that the acceleration of moving target on the radar signal processing is getting higher, the acceleration ambiguity function of the linear frequency modulation (LFM) radar signal is studied. The mathematical analysis demonstrates that for a monostatic radar, the spectrum bandwidth of Doppler frequency widens gradually with the increase of target acceleration till some peaks appear, and the Doppler frequency resolution degrades synchronously. The shape of bistatic acceleration ambiguity function is affected by the position of the target. Decreasing the baseline range or changing the look angle of the receiver can improve the target acceleration resolution of bistatic radar. Matlab simulation proves the effectiveness of this method. The results can also provide significant information for analysis of monostatic and bistatic radar detection performance to accelerate target.
A bacterial global regulator forms a prion

Prions enter another domain of life Prions are self-propagating protein aggregates, discovered in connection with the fatal transmissible spongiform encephalopathies in mammals. Prions have also been identified in fungi, where they act as protein-based elements of inheritance. Although prions have been uncovered in evolutionarily diverse eukaryotic species, it is not known whether prions exist in bacteria. Yuan and Hochschild report the identification of a bacterial protein—the transcription termination factor Rho from Clostridium botulinum—that exhibits the defining hallmarks of a prion-forming protein. Science, this issue p. 198 A bacterial protein that forms a prion establishes the existence of protein-based heredity in the bacterial domain of life. Prions are self-propagating protein aggregates that act as protein-based elements of inheritance in fungi. Although prevalent in eukaryotes, prions have not been identified in bacteria. Here we found that a bacterial protein, transcription terminator Rho of Clostridium botulinum (Cb-Rho), could form a prion. We identified a candidate prion-forming domain (cPrD) in Cb-Rho and showed that it conferred amyloidogenicity on Cb-Rho and could functionally replace the PrD of a yeast prion-forming protein. Furthermore, its cPrD enabled Cb-Rho to access alternative conformations in Escherichia coli—a soluble form that terminated transcription efficiently and an aggregated, self-propagating prion form that was functionally compromised. The prion form caused genome-wide changes in the transcriptome. Thus, Cb-Rho functions as a protein-based element of inheritance in bacteria, suggesting that the emergence of prions predates the evolutionary split between eukaryotes and bacteria.
Compact Broadband Dual Coupling-Feed Circularly Polarized RFID Microstrip Tag Antenna Mountable on Metallic Surface

A square-shaped microstrip RFID tag antenna designed for 915 MHz band is proposed. The antenna is capacitively excited by a dual-offset coupling feed network with one of the feed lines a quarter-wavelength longer than the other. By selecting appropriate dimensions for the coupled lines and feed-lines, along with desirable coupling distance between the coupled line and square patch, the input impedance of the proposed tag antenna can be easily controlled, which results in excellent impedance matching. Moreover, by incorporating the dual-offset feed technique with the method of embedding a cross slot of unequal arm lengths into the square patch, the bandwidth of the circularly polarized (CP) operation can be enhanced. The measured 6-dB return-loss bandwidth of the tag antenna is 25 MHz (902-927 MHz), and its corresponding 3-dB axial-ratio (AR) bandwidth is 20 MHz (903-923 MHz). Further experimental results show that the proposed tag antenna can provide slightly better reading range and gain when mounted on a large metallic surface.