Miracle-dz/UniFAR-FTUs huggingface dataset:
A compact dual band filter-antenna subsystem for 802.11 Wi-Fi applications

A compact dual band filter-antenna subsystem is proposed by using stepped impedance resonator filter and hybrid dual band antenna. The filter is incorporated in LTCC (Low Temperature Co-fired Ceramics) technology. A half cylindrical DRA is excited by a planar monopole antenna to achieve dual band response, moreover the filter-antenna subsystem is proposed, by integrating the filter and the antenna in the same package, utilizing the same technology.
Fine structure in magnetization of individual fluxoid states

Each time a vortex enters or exits a small superconductor, a different fluxoid state develops which can be characterized by its vorticity, i.e., the number of fluxoids inside. We have studied magnetization response of such individual states and found clear signatures of first and second order transitions within the states, which reveal the existence of distinct vortex phases for a fixed number of fluxoids. We attribute the transitions to the merger of individual vortices into a single giant vortex and switching between different arrays of vortices.
Risperidone Compared with Both Lithium and Haloperidol in Mania: A Double‐Blind Randomized Controlled Trial

Case reports and studies of other neuroleptics suggest the efficacy of risperidone in the treatment of mania. Forty-five inpatients with DSM-IV mania were studied in a 28-day randomized, controlled, double-blind trial of either 6 mg daily of risperidone, 10 mg daily of haloperidol, or 800 to 1200 mg daily of lithium. The patients in all three groups showed a similar improvement on the total score for all rating scales at day 28 (Brief Psychiatric rating scale: lithium 9.1, haloperidol 4.9, risperidone 6.5, F = 1.01, df = 2, p = 0.37; Mania rating scale: lithium 15.7, haloperidol 10.2, risperidone 12.4, F = 1.07, df = 2, p == 0.35 [analysis of variance]). The Global Assessment of Functioning and Clinical Global Impression data showed a similar pattern of improvement. This study suggests that risperidone is of equivalent efficacy to lithium and haloperidol in the management of acute mania. The extrapyramidal side effects of risperidone and haloperidol were not significantly different.
Melatonin Binding Sites in the Ovine Brain and Pituitary: Characterization During the Oestrous Cycle

The distribution of putative melatonin receptors in the sheep has been investigated using in vitro autoradiography and the high affinity, high specific activity ligand 2‐[125l]iodomelatonin. A wide distribution of specific labelling was found in both the ovine brain and pituitary gland as previously reported. Several novel areas of binding were also identified in the present study, including a fine layer of labelling at the medial edge of the diagonal band of Broca, the trigeminal nucleus, laminae II and III of the substantia gelatinosa, the molecular layer of the cerebellum as well as a scattered labelling in the pars distalis of the pituitary. There was no evidence of specific labelling in any of the peripheral tissues examined.
Response of bats to light with different spectra: light-shy and agile bat presence is affected by white and green, but not red light

Artificial light at night has shown a remarkable increase over the past decades. Effects are reported for many species groups, and include changes in presence, behaviour, physiology and life-history traits. Among these, bats are strongly affected, and how bat species react to light is likely to vary with light colour. Different spectra may therefore be applied to reduce negative impacts. We used a unique set-up of eight field sites to study the response of bats to three different experimental light spectra in an otherwise dark and undisturbed natural habitat. We measured activity of three bat species groups around transects with light posts emitting white, green and red light with an intensity commonly used to illuminate countryside roads. The results reveal a strong and spectrum-dependent response for the slow-flying Myotis and Plecotus and more agile Pipistrellus species, but not for Nyctalus and Eptesicus species. Plecotus and Myotis species avoided white and green light, but were equally abundant in red light and darkness. The agile, opportunistically feeding Pipistrellus species were significantly more abundant around white and green light, most likely because of accumulation of insects, but equally abundant in red illuminated transects compared to dark control. Forest-dwelling Myotis and Plecotus species and more synanthropic Pipistrellus species are thus least disturbed by red light. Hence, in order to limit the negative impact of light at night on bats, white and green light should be avoided in or close to natural habitat, but red lights may be used if illumination is needed.
Local Muscular Fatigue and Attentional Processes in a Fencing Task

Study of the effects of brief exercise on mental processes by Tomporowski and Ellis (1986) has shown that moderate muscular tension improves cognitive performance while low or high tension does not. Improvements in performance induced by exercise are commonly associated with increase in arousal, while impairments are generally attributed to the effects of muscular or central fatigue. To test two hypotheses, that (1) submaximal muscular exercise would decrease premotor time and increase motor time in a subsequent choice-RT task and (2) that submaximal muscular exercise would increase the attentional and preparatory effects observed in premotor time 9 men, aged 20 to 30 years, performed an isometric test at 50% of their maximum voluntary contraction between blocks of a 3-choice reaction-time fencing task. Analysis showed (1) physical exercise did not improve postexercise premotor time, (2) muscular fatigue induced by isometric contractions did not increase motor time, (3) there was no effect of exercise on attentional and preparatory processes involved in the postexercise choice-RT task. The invalidation of hypotheses was mainly explained by disparity in directional effects across subjects and by use of an exercise that was not really fatiguing.
Impact of Intra-LTE Handover with Forwarding on the User Connections

In order to ensure long-term competitiveness of 3G technology, a new study item has been started by 3GPP to define the long term evolution (LTE) of 3G. The scope of the LTE concept is to improve the system performance in terms of data rate, throughput, latency, coverage and cost. LTE introduces a pure packet based architecture, with distributed mobility management, where active mode handover decisions are done by E-UTRAN Node-Bs (eNB). During handover, downlink user data is forwarded between the involved eNBs. This paper provides an overview of the LTE and the intra-MME/SAE Gateway handover procedure. The impact of the forwarding on the user connections is evaluated with NS2 based simulations.
The effect of paroxetine on the quantitative EEG

Quantitative human electroencephalograph (EEG) methods have a well documented application in human psychopharmacology (1,2). They are used to identify drugs which affect the central nervous system, specify the times of drug activity, compare and classify drugs, and relate EEG findings to other measured effects. The EEG signal is most commonly quantified in fixed frequency bands, using power spectral density analysis. Drug effects are defined as those EEG changes after drug administration that differ statistically from the changes seen with placebo. Paroxetine is a phenylpiperidine compound that inhibits 5-hydroxytryptarnine (5-HT) uptake and has been reported to have antidepressant properties (3,4). In this respect, parmetine is considerably more potent and selective than tricyclic antidepressants such as imipramine and arnitriptyline. The most frequently used clinical daily dose ofparoxetineis 30mg. Thestudy reportedhere examined the effects of 30mg of paroxetine on the quantitative EEG in comparison with amitriptyline (75mg) and placebo.
A simplified power management strategy for a supercapacitor/battery Hybrid Energy Storage System using the Half-Controlled Converter

Hybrid Energy Storage Systems (HESS), which is commonly used in Electric Vehicles (EV), is a combination of two energy storage devices. Supercapacitors (SC) due to their high charge/discharge rate, high power density, long lifetime in comparison to batteries, and capability of supporting high stress represent an optimal solution for HESS when combining with batteries. In such HESS configuration dc-dc converter is needed. Half-Controlled Converters (HCC) is an excellent solution due to their low cost and similar efficiency in comparison to the most used types of converters. In this paper, a strategy for power distribution between SC and battery, based on current control and a filter decoupling technique is proposed, along with the method to evaluate the decoupling frequency. The proposed strategy overtakes other approaches, such as fuzzy control or neural network, in terms of a faster and less complex implementation.
Robust Analysis of Network based Recommendation Algorithms against Shilling Attacks

Despite their great adoption in e-commerce sites, recommender systems are still vulnerable to unscrupulous producers who try to promote their products by shilling the systems. In the past decade, network based recommendation approaches have been demonstrated to be both more efficient and of lower computational complexity than collaborative filtering methods, however as far as we know, there is rare research on the robustness of network based recommendation approaches. In this paper, we conducted a serious of experiments to examine the robustness of five typical network based recommendation algorithms. The empirical results obtained from the movielens dataset show that all the two limited knowledge shilling attacks are successful against the network based algorithms, and the bandwagon attack affects very strongly against most network based recommendation algorithms, especially the algorithms considering the preferential diffusion at the last step. One way to relieve the attack impact is to assign the algorithm a heterogeneous initial resource configuration.
Automatic classification of sleep stages using EEG records based on Fuzzy c-means (FCM) algorithm

Currently in the world there is an alarming number of people who suffer from sleep disorders. A number of biomedical signals, such as EEG, EMG, ECG and EOG are used in sleep labs among others for diagnosis and treatment of sleep related disorders. The usual method for sleep stages classification is visual inspection by a sleep specialist. This is a very time consuming and laborious exercise. Automatic sleep stages classification can facilitate this process. In this work an attempt was made to classify six sleep stages consisting of Awake, Stage1, Stage2, Stage3, Stage4, and REMS. Spectral analysis, Wavelet transform and Fuzzy clustering based on fuzzy c-means algorithm (FCM) were deployed for this purpose. Twelve recordings of a healthy six stages studied per 30s epochs. The results demonstrated that the performance for automatically discriminated for these six sleep stages from each other when using wavelet packet with sym3 where the classification was with average 92.27%.
IGF binding protein‐6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis

Hypoxia stimulates tumor angiogenesis by inducing the expression of angiogenic molecules. The negative regulators of this process, however, are not well understood. Here, we report that hypoxia induced the expression of insulin‐like growth factor binding protein‐6 (IGFBP‐6), a tumor repressor, in human and rodent vascular endothelial cells (VECs) via a hypoxia‐inducible factor (HIF)‐mediated mechanism. Addition of human IGFBP‐6 to cultured human VECs inhibited angiogenesis in vitro. An IGFBP‐6 mutant with at least 10,000‐fold lower binding affinity for IGFs was an equally potent inhibitor of angiogenesis, suggesting that this action of IGFBP‐6 is IGF‐independent. The functional relationship between IGFBP‐6 and vascular endothelial growth factor (VEGF), a major hypoxia‐inducible angiogenic molecule, was examined. While VEGF alone increased angiogenesis in vitro, co‐incubation with IGFBP‐6 abolished VEGF‐stimulated angiogenesis. The in vivo role of IGFBP‐6 in angiogenesis was tested in flk1:GFP zebrafish embryos, which exhibit green fluorescence protein in developing vascular endothelium, permitting visualization of developing blood vessels. Injection of human IGFBP‐6 mRNA reduced the number of embryonic inter‐segmental blood vessels by ∼40%. This anti‐angiogenic activity is conserved in zebrafish because expression of zebrafish IGFBP‐6b had similar effects. To determine the anti‐angiogenic effect of IGFBP‐6 in a tumor model, human Rh30 rhabdomyosarcoma cells stably transfected with IGFBP‐6 were inoculated into athymic BALB/c nude mice. Vessel density was 52% lower in IGFBP‐6‐transfected xenografts than in vector control xenografts. These results suggest that the expression of IGFBP‐6 in VECs is up‐regulated by hypoxia and IGFBP‐6 inhibits angiogenesis in vitro and in vivo.
Commonsense for Making Sense of Data Sreyasi

In my doctoral research, I address the problem of automatically acquiring commonsense knowledge from text corpora and also from data-sets containing visuals (images, videos) along with textual descriptions. I also aim to exploit the acquired commonsense knowledge for domain-specific and domain-independent applications such as fine-grained search, retrieval and prediction, data integration and analytics using qualitative reasoning.
TULAREMIA IN DEER MICE (PEROMYSCUS MANICULATUS) DURING A POPULATION IRRUPTION IN SASKATCHEWAN, CANADA

Type B tularemia caused by Francisella tularensis subsp. holarctica was diagnosed in deer mice (Peromyscus maniculatus) found dead at four sites in west-central Saskatchewan during April and May 2005. The occurrence of tularemia coincided with a decline in the number of deer mice in part of a large area (>22000 km2 ) in which deer mice had been extremely abundant during the autumn of 2004 and spring of 2005, and in which mice caused damage to crops in the autumn of 2004. This is apparently the first report of tularemia as a cause of death of wild deer mice. The bacterium isolated from deer mice was atypical in that cysteine was not required in the media used for isolation. Three isolates tested were genotypes not previously identified in Canada. There were no reports of human disease in the area.
Airway inflammation and asthma.

Asthma is currently identified by the presence of characteristic symptoms of wheezing, chest tightness, dyspnea and cough, and by the presence of reversible airway narrowing and/or airway hyperresponsiveness to a variety of inhaled bronchoconstrictor stimuli. Airway inflammation appears to be central to the pathogenesis of all of these clinical manifestations of asthma. There are increased numbers of activated eosinophils and of mast cells in the airways of patients with asthma, even those with mild disease. The presence and survival of these inflammatory cells may be promoted by the presence of increased levels of proinflammatory cytokines, such as GM‐CSF, interleukin(IL)‐3 or IL‐5 in asthmatic airways. These cells have the capacity to release potent bronchoconstrictor mediators such as the cysteinyl leukotrienes, which are responsible, in part at least, for airway narrowing in asthma and for allergen‐g exercise‐ and aspirin‐induced asthma. Other cells, such as a subset of T‐lymphocytes (TH2), may also be important in maintaining the inflammatory cascade through the formation and release of cytokines. Airway structural changes caused by the persisting inflammation, such as airway epithelial damage, or altered smooth muscle function or volume, are likely to be important in the pathogenesis of stable long‐standing airway hyperresponsiveness. Mediators released from the inflammatory cells may be responsible for these changes. Despite the great increase in knowledge about the importance of airway inflammation in the pathogenesis of asthma, the precise sequence of events that leads to the presence of persisting airway inflammatory cells, airway structural changes and airway hyperresponsiveness in asthma remains to be clarified.
Comparison of calibrated chromogenic anti-Xa assay and PT tests with LC-MS/MS for the therapeutic monitoring of patients treated with rivaroxaban

Summary Possibilities to monitor rivaroxaban therapy could be useful in certain circumstances. Prothrombin time (PT) or chromogenic anti-Xa assays such as the Biophen Direct Factor Xa Inhibitor® (DiXaI) have been proposed to estimate rivaroxaban concentrations but are mainly based on in vitro studies. The study aim was to compare PT and Biophen DiXaI® measurements with liquid chromatography-tandem mass spectrometry (LC-MS/MS) measurements in plasma samples from patients treated with Xarelto®. Fifty-two plasma samples were included. PT was performed using Innovin® and Triniclot PT Excel S®. Biophen DiXaI® was performed according to instructions from the manufacturer. The rivaroxaban plasma concentration ranged between 0 and 485 ng/ml as measured by LC-MS/MS. The limits of quantification were 30 ng/ml and 5 ng/ml for Biophen DiXaI® and LC-MS/MS, respectively. The linear correlation between Biophen DiXaI® and LC-MS/ MS analyses was high for all rivaroxaban concentrations (r2 = 0.95). For concentrations ≤100 ng/ml, r2-value was 0.83. The Bland-Altman analysis showed a mean difference of −16 ng/ml (SD: 25 ng/ml). The PT methods did not correlate well with plasma concentrations measured by LC-MS/MS (r2 ≈ 0.60). In conclusion, the important interindividual variability and the poor correlation with LC-MS/MS preclude the use of PT to estimate rivaroxaban concentrations. Thanks to its small inter-individual variability and good agreement with LC-MS/ MS measurements, we recommend the use of Biophen DiXaI® assays to estimate concentrations of rivaroxaban >30 ng/ml. Quantification of low rivaroxaban levels (<30 ng/ml) requires the LC-MS/MS method.
Intrusion Detection System using decision tree algorithm

Intrusion Detection System (IDS) is the most powerful system that can handle the intrusions of the computer environments by triggering alerts to make the analysts take actions to stop this intrusion. IDS's are based on the belief that an intruder's behavior will be noticeably different from that of a legitimate user. A variety of intrusion detection systems (IDS) have been employed for protecting computers and networks from malicious attacks by using traditional statistical methods to new data mining approaches in last decades. However, today's commercially available intrusion detection systems are signature-based that are not capable of detecting unknown attacks. In this paper we analyze a classification model for misuse and anomaly attack detection using decision tree algorithm.
Analysis of facial images using physical and anatomical models

A novel approach is presented to the analysis of dynamic facial images. The approach exploits a realistic model of the human face. The face model, which may be simulated and rendered at interactive rates on a graphics workstation, incorporates a physically-based approximation to facial tissue and a set of anatomically-motivated facial muscle actuators. The authors consider the estimation of dynamic facial muscle contractions from video sequences of expressive human faces. They develop an estimation technique that uses deformable contour models to track the nonrigid motions of facial features in images. The technique computes robust muscle actuator controls, enabling the face model to resynthesize transient expressions accurately. <<ETX>>
Noninvasive Strategies for Systemic Delivery of Therapeutic Proteins — Prospects and Challenges

It is well established that proteins have great physiological importance, thus possess‐ ing great potential for therapeutic use. There is increased interest in protein/peptide pharmaceuticals delivery due to recent improvements in analytical methods, ad‐ vancements in molecular biology and genetic engineering, and a better understanding of regulatory roles of proteins and peptides. There are however major challenges that need to be overcome for systemic delivery of these biological molecules. The major hurdles that contribute to low biological activity are low stability, immunogenicity, and toxicity. A combination of strategies can be used to overcome these challenges and improve the bioavailability of protein drugs. Alternative delivery routes (e.g., na‐ sal and pulmonary) and the development of new methods for overcoming delivery challenges (e.g., nanomedicine, and PEGylation), along with the development of inno‐ vative formulation strategies (e.g., spray-freeze drying, supercritical fluid methods, fluidized-bed spray coating, lyophilization, jet milling and spray drying), have result‐ ed in improved pharmacokinetics of protein drugs and in some cases increased pa‐ tient compliance.
Prevalence of Ehrlichia, Borrelia, and Rickettsial Agents in Amblyomma americanum (Acari: Ixodidae) Collected from Nine States

Abstract Ambyomma americanum (L.) (Acari: Ixodidae) is an aggressive tick that feeds on humans during all postembryonic life stages. In many regions of the United States, it is the tick most commonly found attached to humans. Public health interest has grown recently, due to the recognition of new human pathogens transmitted by A. americanum and the expanding distribution of the tick. A. americanum is a vector of several bacteria pathogenic to humans. Ehrlichia chaffeensis and Ehrlichia ewingii cause moderate-to-severe febrile illness. “Rickettsia amblyommii,” a member of the spotted fever group Rickettsia, also has recently been implicated as a possible human pathogen based on serologic evidence from persons recovering from illness after a tick bite. We have determined the prevalence of infection of Ehrlichia chaffeensis, E. ewingii, “Borrelia lonestari,” and R. amblyommii within A. americanum ticks from 29 sites in nine states. Overall infection prevalences were 4.7% for E. chaffeensis (range, 0–27%), 3.5% for E. ewingii (range, 0–18.6%), 2.5% for B. lonestari (range, 0–12.2%), and 41.2% for R. amblyommii (range, 0–84.0%). In addition, 87 ticks (4.3%) were infected with two or more bacteria. This report documents new distribution records for E. ewingii, B. lonestari, and R. amblyommii and underscores the nonhomogeneous distribution of pathogen foci of infection. Additional surveillance throughout the range of A. americanum is warranted to increase physician and public awareness of the risk of disease to humans from exposure to the agents transmitted by this tick.
Development of a Direct In Situ PCR Method for Detection of Specific Bacteria in Natural Environments

ABSTRACT We applied HNPP (2-hydroxy-3-naphthoic acid-2′-phenylanilide phosphate) to direct in situ PCR for the routine detection of specific bacterial cells at the single-cell level. PCR was performed on glass slides with digoxigenin-labeled dUTP. The digoxigenin-labeled PCR products were detected with alkaline phosphatase-labeled antidigoxigenin antibody and HNPP which was combined with Fast Red TR. A bright red fluorescent signal was produced from conversion to HNP (dephosphorylated form) by alkaline phosphatase. We used the ECOL DNA primer set for amplification of ribosomal DNA of Escherichia coli to identify cells specifically at the single-cell level in a bacterial mixture. High-contrast images were obtained under an epifluorescence microscope with in situ PCR. By image analysis,E. coli cells in polluted river water also were detected.