Miracle-dz/UniFAR-FTUs huggingface dataset:
THE EFFECT OF USING DIFFERENT LEVELS OF CINNAMON AND THYME POWDER ON EGG CHARACTERISTICS AND FATTY ACIDS PROFILE IN JAPANESE QUAILS *

The present study was conducted to investigate the effect of using different levels of Cinnamon (Cinnamomum verum) and Thyme (Thymus vulgaris) powder supplementation on egg characteristics and fatty acids profile in Japanese quails (Coturnix japonica). A total of one hundred 42 days old Japanese quailswere distributed randomly into five groups as a completely randomized design. The groups were subdivided into five replicates with 4 quails each. The experiment was continued 42 to 105 days. Quails were fed by basal diet as control; basal diet contained 1 and 2 percentage turmeric and thyme powder. In 56, 84 and 105 days a total of 10 eggs from each cage were collected and egg characteristics such as egg mass weight, egg yolk weight, egg shell weight, egg white weight and egg shell thickness were evaluated. Also the fatty acids profiles of eggs were determined. Data from this study showed that there were no significant effects between treatments for egg mass weight. The result showed that egg shell weight and egg shell thickness increased significantly compared to the control (p≤0.05). As result revealed myristic acid (C14:0), palmitic acid (C16:0) decreased significantly but stearic (C18:0) didn’t changed by cinnamon and thyme supplementation (p≤0.05). Data obtained from this study showed that palmitoleic (C16:1), oleic (C18:1), linoleic (C18:2), arachidonic acid (C20:4), eicosapentaenoic acid (C20:5) acids increased (p≤0.05) and linolenic acid (C18:3) and docosahexaenoic acid (C22:6) didn’t change numerically compared to the control. Result also showed that saturated fatty acids (SFA), monounsaturated fatty acid (MUFA) and polyunsaturated fatty acids (PUFA) differed by using thyme and cinnamon powder compared to the control. In conclusion we could suggested that dietary inclusion of cinnamon and thyme powder at 1 and 2 percentage could have decrease saturated fatty acids and increase unsaturated fatty acids in the eggs of experimental Japanese quails.
Combination therapy with anti‐mediator drugs in allergic disease

Inflammatory mediators are local hormones that act via specific cell-surface receptors in an autocrine or paracrine manner to modulate the behaviour of inflammatory leucocytes and structural cells in inflamed tissues. The classical inflammatory mediators are the autacoids such as histamine, cysteinyl-leukotrienes (cys-LT), LTB4, prostanoids, bradykinin, and platelet-activating factor (PAF). Potent, selective, safe and long-acting compounds that inhibit the synthesis or block the receptors of individual autacoids have been developed over the last 20 years. The leukotriene (LT) modifiers (montelukast, pranlukast, zafirlukast, zileuton) have entered clinical practice for asthma, and the non-sedating H1 histamine antagonists (cetirizine, loratadine, terfenadine) are front-line therapies for allergic rhinitis and allergic skin disease. Potent inhibitors of prostanoid synthesis (NSAIDs) have been available for 100 years, but the new cycloxygenase-2-selective inhibitors (celecoxib, rofecoxib) may combat inflammation without the gastric and other adverse effects associated with traditional NSAIDs. Experimental antagonists of LTB4, PAF and the mast cell protease, tryptase, have also been investigated in clinical trials in asthma and other diseases, with mixed results. LT modifiers and other anti-mediator therapies have been shown to provide excellent clinical benefit in significant subgroups of patients. Many have advantages with respect to patient compliance and favourable adverse effect profiles compared to anti-inflammatory corticosteroids. The perception emerging from clinical trials is that anti-mediator monotherapies may be less efficacious than corticosteroids against the broad spectrum of inflammatory processes in allergic disease, arousing growing interest in the concept of combination therapy with two or more antimediator drugs, not only in asthma but also in inflammatory diseases of the nasal airway and skin. The paper from Professor Lipworth's group at Dundee University published in this issue of Clinical & Experimental Allergy [1] provides important evidence that combination therapy with two anti-mediator drugs, specifically a LT modifier and an H1 histamine antagonist, can provide additive and complementary anti-inflammatory outcomes that match those afforded by topical corticosteroids. This review will focus on clinical trials of anti-mediator cotherapy, particularly with combinations of LT modifiers and antihistamines, in the treatment of allergic asthma, exercise-induced bronchoconstriction, allergic skin disease (eczema, urticaria), and allergic rhinitis.
Genetic architecture, biochemical underpinnings and ecological impact of floral UV patterning

Floral attraction traits can significantly affect pollinator visitation patterns, but adaptive evolution of these traits may be constrained by correlations with other traits. In some cases, molecular pathways contributing to floral attraction are well characterized, offering the opportunity to explore loci potentially underlying variation among individuals. Here, we quantify the range of variation in floral UV patterning (i.e. UV ‘bulls‐eye nectar guides) among crop and wild accessions of Brassica rapa. We then use experimental crosses to examine the genetic architecture, candidate loci and biochemical underpinnings of this patterning as well as phenotypic manipulations to test the ecological impact. We find qualitative variation in UV patterning between wild (commonly lacking UV patterns) and crop (commonly exhibiting UV patterns) accessions. Similar to the majority of crops, recombinant inbred lines (RILs) derived from an oilseed crop × WI fast‐plant® cross exhibit UV patterns, the size of which varies extensively among genotypes. In RILs, we further observe strong statistical‐genetic and QTL correlations within petal morphological traits and within measurements of petal UV patterning; however, correlations between morphology and UV patterning are weak or nonsignificant, suggesting that UV patterning is regulated and may evolve independently of overall petal size. HPLC analyses reveal a high concentration of sinapoyl glucose in UV‐absorbing petal regions, which, in concert with physical locations of UV‐trait QTLs, suggest a regulatory and structural gene as candidates underlying observed quantitative variation. Finally, insects prefer flowers with UV bulls‐eye patterns over those that lack patterns, validating the importance of UV patterning in pollen‐limited populations of B. rapa.
A model of visual attention detection based on phase spectrum

Visual attention detecting has drawn great research interest due to its useful application in the area of multimedia. Recently, a fast spectral residual approach in frequency domain was proposed to find the Region of Interest in an image. It was proved to be able to give better performance than the classic approaches. In this paper, we propose a new model for Region of Interest detection based on the phase spectrum. First, we analyze the reason that the salient region can create “pop-out” in the feature maps of the phase spectrum in spatial domain. Second, in order to obtain better feature maps, we propose to blur the image and then get the feature maps based on the phase spectrum of the blurred image. Last, we present a model to generate Region of Interest accordingly. Experimental results show that our approach achieves better and more robust results than that from the state-of-the-art.
A partial BRCA1 sequence homology mapping to 4q28

Using a BRCA1 cDNA probe in Southern analysis, we detected a sequence of 348 bp on 4q28 that is homologous to the 3′ end of BRCA1. A 28-kb sequence contig has been assembled spanning the homologous region, which we designated BRCA1-h. An open reading frame was identified encoding a sequence of 82 amino acids; 22 of the last 23 amino acids are identical to the last 23 residues of BRCA1. BLAST-searches, RT-PCR and RACE-experiments have been unable to provide evidence that BRCA1-h is part of an expressed gene.
Design and analysis of a hybrid axial field flux-switching permanent magnet machine

A Hybrid Axial Field Flux-Switching Permanent Magnet machine (HAFFSPMM) which is suitable for electrical vehicle drive is proposed in this paper. The size equations of the HAFFSPMM, including the power-size equations and the winding part, are deduced. According to the equations, a 3-phase 6/10 stator/rotor-pole HAFFSPMM is designed and the electromagnetic performances, such as the PM flux linkage, no-load back-EMF, cogging torque, torque-current characteristic and the field regulation capacity, are investigated based on 3-D finite element method (FEM). A prototype is manufactured and the experiments are done, which validates the design method and the predicted FEM analysis.
Peer Reviewing Short Answers using Comparative Judgement

We propose a comparative judgement scheme for grading short answer questions in an online class. The scheme works by asking students to answer short answer questions. Then a multiple choice question is created whose choices are the answers given by students. We show that we can formulate a probabilistic graphical model for this scheme which lets us infer each students proficiency for answering and grading questions.
Genomic Modeling of Atherosclerosis in Peripheral Arterial Disease and Its Variant Phenotype in Patients with Diabetes

Microarrays can be used to discover candidate genes associated with peripheral arterial disease (PAD) and develop models that predict patient clinical status. We hypothesize that multiple phenotypes of PAD with distinct patterns of gene expression exist. We histologically characterized and extracted ribonucleic acid from 31 arterial samples collected from the lower extremities of patients undergoing amputation or free fibular grafting. Analysis using the Affymetrix U133A microarray identified 335 genes with twofold or greater differences in expression between normal and diseased arteries (p < .01) and 104 genes with twofold or greater differences between diabetic and nondiabetic atherosclerotic arteries (p < .1). Many genes identified have known roles in inflammatory and lipid uptake pathways. Predictive models were developed that could predict PAD and the associated diabetic phenotype with an accuracy of 71 to 90%. Developing distinct genomic models of PAD will serve as the first step toward understanding the molecular and genetic basis of PAD and subsequent application of novel therapeutics to this condition.
Comparative Study of Factors Relating to HIV Risk Level of Black Homeless Women

A comparative study was conducted to assess factors that relate to level of HIV risk of black homeless women. The study examined whether 460 black women categorized as high, moderate, or low risk for HIV infection differed in environmental, demographic, and personal factors; appraisal of threat; resources; coping responses; and health outcome. Multivariate analyses of variance revealed high-risk homeless women reported statistically significant and greater concerns, appraisal of threat, emotion-focused coping, depression, and emotional distress, as well as less self-esteem and sense of coherence than moderate- and low-risk homeless women. Discriminant analyses revealed that women at high risk for HIV infection were best differentiated from moderate- and low-risk women by greater use of emotion-focused coping, greater severity of concerns, greater depression, and less self-esteem. An understanding of psychosocial factors most predictive of groups at highest risk for HIV infection provides impetus for interventional programs focused on altering the course of the disease in this population.
Robot to Business: Informationstechnisch gestützte Dienstleistungen in mobilen und verteilten Umgebungen - ein ganzheitlicher Ansatz

Die Anreicherung von Produkten um Dienstleistungen hin zu einer hybriden Wertschöpfung erfordert innovative informationstechnische Lösungen. Informationstechnisch gestützte Dienstleistungen in einem hoch dynamischen Umfeld bringen zusätzlich besondere Herausforderungen mit sich. Die Randbedingungen sind einem ständigem Wechsel unterzogen, die Teilnehmer mobil und nicht permanent in Kommunikationsnetze eingebunden. Anhand des mit Mitteln des Bundesministeriums für Wirtschaft und Technologie geförderten Projektes Robot to Business wird ein ganzheitlicher Lösungsansatz entworfen, der generisch anwendbar ist, um Dienstleistungen im mobilen und verteilten Umfeld zu definieren, einschließlich der Unterstützung für die automatisierte Ausführung.
International Family Nursing Association Position Statement on Advanced Practice Competencies for Family Nursing

The International Family Nursing Association (IFNA) is the principal organization of family nurses globally. IFNA members practice in a variety of settings, including traditional health care organizations, academia, governments, independent private practices, international health organizations, and others. IFNA brings together nurses to promote health for families worldwide through family nursing practice, education, research, and advocacy to advance the health care delivery for families. IFNA recognizes that international variation exists between countries regarding advanced practice educational preparation and roles related to advanced practice nursing with families. The intent of this document is to formulate a clear vision of Advanced Practice Competencies for Family Nursing and to provide a foundational standard for family nurse leaders to draw from to shape the future direction for enactment of the role, dependent on regulations in each country.
A Flying-Capacitor Modular Multilevel Converter for Medium-Voltage Motor Drive

This paper presents a flying-capacitor modular multilevel converter (FC-MMC) based on series-connected submodules. It is intended for completely improving the performance of a medium-voltage motor drive system in the entire speed range especially at zero/low speed under rated torque condition. The proposed FC-MMC circuit is characterized by the cross connection of upper and lower arm middle taps through a flying capacitor in per phase leg. By properly controlling the ac current flowing through the flying capacitor, the power balance between upper and lower arms is achieved, leading to very small voltage ripples on submodule dc capacitors in the entire speed range from standstill to rated speed even under the rated torque condition. Meanwhile, no common-mode voltage is injected. Simulation results obtained from a 4160-V 1-MW model show that the proposed FC-MMC along with the proposed control method performances satisfactorily in dynamic and static state even when operated at zero/low speed. Experiments on a downscaled prototype also prove the effectiveness of the proposal.
Infectivity of Hepatic Strain Klebsiella pneumoniae in Diabetic Mice

Besides urinary tract infection (UTI) and pneumonia, increased severe liver abscesses caused by Klebsiella pneumoniae (KP), especially in diabetic patients, have been observed in infections acquired in hospitals. This indicates that different KP strains with higher virulence have emerged in recent years. Our goal was to investigate the infectivity of KP isolates in mice from liver abscess or UTI patients. Mice were injected with streptozotocin to induce diabetes. Male ICR mice were infected with KpU1 (UTI strain CG3 for survival experiment only) and KpL1 (liver abscess strain CG5) by tail-vein injection of 5 × 104 colony-forming units (CFU) bacterial suspension. The mice survival rates, cytokine level by enzyme-linked immunosorbent assay (ELISA), and bacterial presence in liver tissue by Giemsa stain were examined. The survival rates for the KpL1-infected animals were 28% and 0% in normal and diabetic groups, respectively, whereas, for the KpU1-infected mice, the rates were 100% and 75% during a 30-day observation. Nonsurviving KpL1-infected mice showed >105 bacteria/ml blood and the bacteria appeared in the liver sinus area and inside liver cells. The KpL1-infected mice showed a tendency to increase the blood interleukin 1β (IL-1β) level in both nondiabetic and diabetic groups, whereas the tumor necrosis factor-Α (TNF-Α) level was significantly decreased in the KpL1-infected diabetic mice (P = 0.002). In conclusion, the KP strain from liver abscess showed a greater virulence in mice than the KP from UTI and was more virulent in diabetic than in nondiabetic mice. The infection with KP from liver abscess significantly decreased the blood TNF-Α level in diabetes mellitus (DM) mice and the blood IL-1β level tended to increase in both infected nondiabetic and diabetic groups. High blood bacterial count and appearance of bacteria in liver sinus and cells usually contribute to death of the animals.
Un modelo para corregir el error de medida en el análisis de la movilidad de la renta

Este trabajo considera un modelo de Markov mixto latente para corregir el error de medida que afecta a los datos de renta y, por tanto, al analisis de su movilidad. De esta manera, el estudio muestra, en primer lugar, los resultados observados de la transicion y, mas tarde, el modelo proporciona la transicion latente, mejorando la fiabilidad del analisis. Los datos analizados corresponden a los microdatos de la Encuesta Continua de Presupuestos Familiares para el ano 1995.
Retrohippocampal, hippocampal and related structures of the forebrain in the reeler mutant mouse

Retrohippocampal, hippocampal and some related forebrain regions of the reeler mutant mouse were examined in cresyl violet and myelin stained preparations. All cortical structures are abnormal. The entorhinal cortex, parasubiculum, presubiculum, subiculum, and anterior hippocampal cortex share an anomaly of common quality. All lack an external plexiform layer and their neurons are not arranged in the usual laminae. The positions of neurons are not random, however. Cells of smaller average size and of polymorphic shape are grouped in an outer relatively narrow zone external to a broad zone of larger cells. The histological features of these two cell zones in the mutant are similar to the deep polymorphic cell stratum and the superjacent pyramidal field respectively in the normal animal, but their relative depths in the cortex are reversed. The histological pattern of the mutant hippocampus is less disturbed. Its external plexiform layer is well developed and, although the positions of some neurons are abnormal, there is an explicit laminar pattern and the cytological features of the individual hippocampal cytoarchitectonic fields are readily recognized.
Structural Basis for Lipid-Antigen Recognition in Avian Immunity

CD1 proteins present self- and foreign lipid Ags to activate specific T cells in the mammalian immune system. These T cells play an important role in controlling autoimmune diseases, suppression of tumor growth, and host defense against invading pathogens. Humans use five CD1 isoforms, whereas only two exist in birds. Unlike mammals’ CD1, the structure of chicken CD1-2 showed a primitive lipid-binding groove, suggesting that chicken may only recognize single-chain lipids. In contrast, the crystal structure of the second chicken CD1 isoform, chCD1-1, reported in this study at 2.2 Å resolution, reveals an elaborated binding groove with a dual-pocket, dual-cleft architecture. The A’ and F’ deep pockets are separated from each other, but each is connected to a hydrophobic surface cleft, which may participate in lipid binding. The long endogenous ligand found inside the binding groove of chCD1-1, together with binding data on various glycolipids and mycolic acid, strongly suggest that the unique avian CD1 family could bind long dual- and possibly triacyl-chain lipids.
Analysis of theatrical effects in multimedia picture story show

Impressions of combinations of lighting patterns, lyrics and music are analyzed for designing the system which generates the theatrical effects using the three modal media based on adjectives representing producer's impressions of story scenes. Impression spaces of three modal media are constructed by factor analysis using data obtained by pre-experiments. The three modal media are generated according to the coordinates in the impression spaces of three modal media, where the coordinates are estimated using the concept of co-occurrence of inputted adjectives. In this paper, subject experiments are performed to analyze the interaction of combinations of the three modal media. The following four combinations are considered: (1) combinations based on same adjectives, (2) combinations based on counter adjectives, (3) combinations based on similar adjectives, (4) combinations based on dissimilar adjectives. Experimental results show that combinations (1),(3), and (4) are effective as theatrical effects of story scenes.
Mechanomyographic and electromyographic responses to eccentric muscle contractions

Little is known regarding the modulation of torque during eccentric muscle actions. Mechanomyographic (MMG) and electromyographic (EMG) signals have been used to examine motor control strategies. The purpose of this study was to examine the MMG and EMG amplitude and frequency in relation to torque during eccentric muscle contractions. Eight women performed eccentric leg extension muscle contractions at 10–100% of peak torque (PT). A piezoelectric crystal contact sensor and bipolar surface electrodes were placed on the vastus medialis to detect the MMG and EMG signals. Polynomial regression analyses indicated that EMG amplitude (r2 = 0.994) and MMG wavelet center frequency (CF) (r2 = 0.846) increased linearly to 100% eccentric PT, whereas there were no significant relationships for EMG wavelet CF or MMG amplitude and eccentric torque. These results suggested that eccentric torque is primarily modulated through changes in motor unit firing rate. Muscle Nerve, 2006
3D time-contingent physical unclonable function array on 16nm FinFET dielectric RRAM

The randomness and unpredictability of Random Telegraph Noise (RTN) of 16nm FinFET Dielectric (FIND) RRAM is firstly implemented to Time-Contingent Physical Unclonable Function (PUF) application. A novel 3D Time-Contingent Physical Unclonable Function (TC-PUF) realized by 1Kbit 16nm FinFET Dielectric (FIND) RRAM has been newly proposed and demonstrated on a pure 16nm FinFET CMOS logic technology. The new TC-PUF RRAM shows wide operation ranges of voltages and temperatures, and Randomness test confirms the feasibility and stability of the TC-PUF RRAM in the frequency, unpredictability, and long-run continuity.
Sensitivity of the anterior lateral line to natural stimuli in the oyster toadfish, Opsanus tau (Linnaeus)

SUMMARY Inductive neural telemetry was used to record from microwire electrodes chronically implanted into the anterior lateral line nerve of the oyster toadfish, Opsanus tau (L.). The lateral lines of free-ranging toadfish were stimulated by the swimming movements of a prey fish (Fundulus heteroclitus), and the corresponding neural activity was quantified. Both spontaneously active and silent afferent fibers experienced an increase in neural firing as the prey approached the lateral line. Activity was evoked when the prey fish approached to within 8-12 cm of the neuromast, with increases in nerve firing rates directly correlated with diminishing distance. Thus, adult toadfish (28 cm standard length; 33 cm total length) were only able to detect mobile prey that approached within approximately 40% of their body length. Both spontaneously active and silent afferent fibers also experienced a dramatic increase in firing during predatory strikes, indicating that the fibers were not inhibited during rapid body movement. This study investigates, for the first time, the neural response of the anterior lateral line to prey stimuli in free-ranging fish.