Miracle-dz/UniFAR-FTUs huggingface dataset:
Análisis de la Calidad de la Gestión de Destinos Turísticos de Sol y Playa

Los servicios turisticos son basicos en el desarrollo economico y para el logro de la competitividad, sin embargo este sector ha carecido de un enfoque integral en el analisis de la calidad de su gestion. En la presente investigacion se realiza un estudio transversal y longitudinal de 6 destinos turisticos de sol y playa y tiene como objetivo: elaborar un conjunto de procedimientos (general y especificos) para el analisis de la calidad de la gestion, con un enfoque integrador; que facilite la gestion de la satisfaccion del cliente, la eficacia, la eficiencia y el posicionamiento competitivo. Los resultados muestran la aplicacion del procedimiento en los principales destinos turisticos de sol y playa del pais y del Caribe.
Distance Relay Impedance Measuring Problems in Presence of Wind Farms

Environmental concerns along with the increasing demand on electrical power, have led to power generation of renewable sources like wind. Connecting wind turbines in large scale powers with transmission network makes new challenges like the impact of these renewable sources on power system protection. This paper studies the impact of fault resistance and its location on voltage and current fundamental frequencies of faulted lines connected to DFIG based wind farms and it will be demonstrated that because of the large differences between these frequencies, impedance measuring of distance relays is inefficient. Hence in these power systems using conventional impedance measurements is not suitable anymore and new impedance measuring approaches are required in distance relays. Full Text: PDF DOI: http://dx.doi. org/10.11591/ijeecs.v1. i3.pp464-479
Administration of dexamethasone per os in finishing bulls. II. Effects on blood parameters used as indicators of animal welfare.

A set of hormonal, haematological and biochemical parameters was used to evaluate the physiological response and welfare status of 14 finishing Marchigiana bulls treated for 49 days with a low daily dosage (0.75 mg/head per day) of dexamethasone per os. Compared to the Control group, dexamethasone decreased cortisol concentrations (42.3 v. 5.7 nmol/l; s.e.d. = 4.17; P < 0.001), and led to the reversal of the leukocyte formula in the animals treated (P < 0.05). Total serum proteins (70.2 v. 73.9 g/l; s.e.d. = 1.55; P < 0.05), in particular β1 globulins (7.5 v. 9.1 g/l; s.e.d. = 0.24; P < 0.01) and fibrinogen (199 v. 258 mg/dl; s.e.d. = 32.70; P < 0.05), increased as a consequence of treatment. Prolonged dexamethasone administration led the bulls to an apparently chronic stress condition. Moreover, the study indicated various blood parameters that might be used by health officials as effective tools in identifying beef cattle suspected of being illegally treated with dexamethasone.
INTESTINAL ABSORPTION OF OLIGOPEPTIDES

My paper, "Psychiatric Indications for the Termination of Pregnancy", was read to a capacity audience in the Todd Hall, B.M.A. Building, Sydney. The highly charged emotional discussion continued for nearly two hours, and I received a terrible battering. In preparing the paper, I had studied approximately 30 references in English and translated French and German. I bent over backwards to be objective. No go-I was fiayed. We hadn't heard of Humanists in 1951. Near the deadline of 11 p.m, Cedric Swanton (recently deceased). Protestant, doyen of psychiatry in N.S. W. , rose and said that he unreservedly supported my conclusion that there are no psychiatric indications for the termination of pregnancy. Twelve months ago the same Cedric Swanton protested against the psychiatric hospitals in N.S. W. being fitted with revolving doors.
Active and Passive Accomplices: The Communal Character of Workplace Bullying

When aggressive organizational members bully others, they rarely do so without accomplices. In the current study, bullied workers (targets) and non-bullied bystanders (witnesses) who observed bullying reported that persistent abuse involved either several harassers or support for solitary harassers. Active accomplices were other aggressors; passive accomplices included upper managers, HR staff, the bullies' peers, and, in some cases, even the targeted persons’ peers. Respondents also believed that organizations were complicit in bullying; in over 70% of the cases, upper management took no action or made the situation worse. The study extends bullying research by revealing the involvement of numerous other organizational members, and it bolsters targeted worker accounts by comparing target and witness perceptions and finding extensive convergence regarding others’ involvement in bullying.
Effects of cooling, cryopreservation and heating on sperm proteins, nuclear DNA, and fertilization capability in mouse

In the present study, we used confocal microscopy and electrophoresis to study the effects of heating to 5 or 100°C or cooling to 4°C or − 196°C on the stability of sperm proteins and DNA. We used intracytoplasmic sperm injection (ICSI) to determine the fertilizing capability of treated spermatoza. It was shown that sperm cryopreservation at − 196°C or cooling at 4°C altered neither protein and DNA profiles nor the sperm fertilization capability, while the protein and DNA profiles of sperm heated at 100°C were irreversibly degraded and inactivated. The proteins of sperm were severely damaged while the nuclear DNA still maintained its integrity when heated to 58°C. Observation by laser confocal microscopy showed that after being heated to 58°C and 100°C, the nuclear of mouse sperm lost their ability to activate oocytes and they could not transform to male pronuclei though the membrane of some sperm could degrade and induce the formation of sperm asters in ICSI oocytes. The results indicate that the use of 58°C heating only causes the degradation of sperm proteins, while the 100°C heating elicits the irreversible degradation of both sperm proteins and nuclear DNA, and the damage of sperm proteins is primarily responsible for the observed decrease in sperm fertilizing capability. Mol. Reprod. Dev. © 2005 Wiley‐Liss, Inc.
Microfilaria in pleural fluid cytology: A rare finding

Lymphatic filariasis is endemic in India and Southeast Asia. Detection of microfilaria is infrequently reported during cytological evaluation of various lesions or body cavity fluids. Presence of microfilaria in pleural fluid cytology is very rare finding even in endemic areas. Few cases of accidental finding of microfilaria have been reported in association with malignant pleural effusion. But pleural effusion of filarial origin is extremely rare manifestation. Here we report a classical case of microfilaria in pleural fluid cytology.
Clinical, biochemical and pathological profiles of 5464 Egyptian chronic hepatitis C-infected patients.

BACKGROUND/AIMS In Egypt, hepatitis C virus (HC is highly endemic with at least 91% are genotype-4. However, HCV-specific burden data for Egypt are scarce. The study aims to identify clinical, biochemical and pathological features of chronic HCV population in Egypt. METHODOLOGY We analyzed retrospective data of 5,464 HCV-antibody and PCR positive patients attending pre-treatment assessment at one of the National Treatment Centers, Cairo, Egypt. RESULTS Chronic HCV patients were males (81.4%) in their productive age, mean body mass index (BMI): 28 kg/m2. Laboratory profile demonstrated mean platelet count 214 x 10(3)/µ L with only 14% having thrombocytopenia, amino-transferases were mildly elevated: mean AST, ALT were 56 and 63 respectively,low viraemia: 50% had viral load <100 (x 10(3)) IU/mL,and median AFP level 3.3 ng/mL. Liver biopsy revealed ≤A2 in 92% of patients; 80% had ≤F2 and 7.3 % had F4 according to the METAVIR score. Meta regression demonstrated that advanced stages of fibrosis were significantly correlated with platelet count, AST/ALT ratio, AFP levels and BMI (p <0.001). However there was no correlation with viral load. CONCLUSIONS To our knowledge, this is the first study on nationwide scale that provided the demographic, biochemical,and histological characteristics for this number of chronic HCV patients presumably genotype-4.
Journal of Geophysical Research: Planets A test for Io’s magma ocean: Modeling tidal dissipation with a partially molten mantle

Magnetic induction measurements and astrometry provide constraints on the internal structure of Io, a volcanically active moon of Jupiter. We model the tidal response of a partially molten Io using an Andrade rheology which is supported by silicate deformation experiments. This model uses material properties similar to the Earth’s mantle and includes feedbacks between partial melting, tidal heat production, and melt transport. We are able to satisfy constraints provided by the measured imaginary part of the tidal Love number Im(k2), the inferred depth and melt fraction of a near-surface partially molten layer, and the observed equatorial concentration of volcanic landforms. We predict a value for the real part of the tidal Love number of Re(k2) = 0.09 ± 0.02, much smaller than the value of Re(k2) ≈ 0.5 predicted for an Io with a fluid magma ocean. Future spacecraft observations should be able to measure this value and test which model is correct.
Autophagy as a Regulatory Component of Erythropoiesis

Autophagy is a process that leads to the degradation of unnecessary or dysfunctional cellular components and long-lived protein aggregates. Erythropoiesis is a branch of hematopoietic differentiation by which mature red blood cells (RBCs) are generated from multi-potential hematopoietic stem cells (HSCs). Autophagy plays a critical role in the elimination of mitochondria, ribosomes and other organelles during erythroid terminal differentiation. Here, the modulators of autophagy that regulate erythroid differentiation were summarized, including autophagy-related (Atg) genes, the B-cell lymphoma 2 (Bcl-2) family member Bcl-2/adenovirus E1B 19 kDa interacting protein 3-like (Nix/Binp3L), transcription factors globin transcription factor 1 (GATA1) and forkhead box O3 (FoxO3), intermediary factor KRAB-associated protein1 (KAP1), and other modulators, such as focal adhesion kinase family-interacting protein of 200-kDa (FIP200), Ca2+ and 15-lipoxygenase. Understanding the modulators of autophagy in erythropoiesis will benefit the autophagy research field and facilitate the prevention and treatment of autophagy-related red blood cell disorders.
Speech is Silver, but Silence is Golden: Some Remarks on the Function(s) of Pauses

Abstract This paper explores additional functions that can be attached to pauses in speech. While traditional concepts have focused on pauses as boundary markers for delimiting purposes and hesitation pauses as signalling the process of planning on the speaker's side, it is worth assuming that pauses can also be used as stylistic devices in order to increase the sense of anticipation on the hearer's side with regard to the information to follow. Drawing on an innovative descriptive model which is based on the identification of the prosodic and syntactic status at tone unit boundaries in the London-Lund Corpus of Spoken English (LLC), this type of pause will be exemplified and functionally analysed. Thus it will be shown that those pauses in speech which are not mere hesitation pauses may, on the one hand, fulfill a segmenting function, but also, on the other hand, a distinctive non-segmenting communicative function: this second function is subsumed under the notion of anticipation pauses.
Tensión en los modelos de comercio y consumo en la Ciudad de México a partir de la expansión de supermercados y plazas comerciales

La globalizacion de empresas productoras de bienes y servicios se acelero desde la decada de los noventa a partir de los procesos de liberalizacion comercial y la desregulacion de las inversiones foraneas. En paises como Mexico ello ha permitido el arribo incesante de numerosos corporativos de supermercados, tiendas departamentales, retailers internacionales y franquicias que se dedican a la distribucion de productos de consumo para amplios segmentos, pero tambien hacia aquellos que buscan formatos de exclusividad en productos de lujo. La rapida expansion de estas formas empresariales destinadas a la circulacion y consumo de bienes y servicios ha puesto en una situacion dificil a los canales tradicionales que aun cuando todavia tienen una amplia presencia, sufren el embate de nuevas formas de negocios que han desarrollado mayores ventajas tecnologicas, logisticas y organizacionales. Debido a ello, en lugares como la Ciudad de Mexico, un lugar donde proliferaron diversas formas de comercio tradicional, hoy se ve inmerso en un complejo proceso de competencia de sus espacios comerciales. 1. BREVE PLANTEAMIENTO DEL PROBLEMA Y OBJETIVOS DE LA INVESTIGACION El comercio al por menor ha registrado en las ultimas dos decadas una profunda transformacion debido a diversos cambios en las practicas y habitos de consumo de la poblacion generadas por el acelerado crecimiento urbano, el retiro del Estado en los programas de abasto popular y la incursion de grandes empresas de supermercados y Centros Comerciales. Bajo este contexto, las grandes ciudades se han vuelo el escenario de procesos de reestructuracion que ocurren en los espacios orientados al consumo. La Ciudad de Mexico, principal zona metropolitana del Mexico con mas de 20 millones de habitantes registrados en el ano 2010, es escenario de estos cambios, pues se pueden advertir distintos fenomenos como una nueva geografia del comercio transformada por una rapida expansion de supermercados y centros comerciales en distintas modalidades y escalas; emergencia de nuevas practicas de consumo del espacio urbano y tendencias hacia una mayor competencia entre distintas modalidades de comercio con un claro desplazamiento de algunos segmentos tradicionales de comercio. Bajo este contexto, el proposito principal de este trabajo es el de explicar de que manera el transito de un modelo de comercio tradicional a otro de corte empresarial, comandado por los supermercados y centros comerciales, genera un marco de creciente competencia y tension por los espacios del comercio en la Ciudad de Mexico.
Laminin and alpha7beta1 integrin regulate agrin-induced clustering of acetylcholine receptors.

The clustering of acetylcholine receptors (AChRs) in the post-synaptic membrane of skeletal muscle is an early developmental event in the formation of the neuromuscular junction. Several studies show that laminin, as well as neural agrin, can induce AChR clustering in C2C12 myofibers. We recently showed that specific isoforms of the alpha7beta1 integrin (a receptor normally found at neuromuscular junctions) colocalize and physically interact with AChR clusters in a laminin-dependent fashion. In contrast, induction with agrin alone fails to promote localization of the integrin with AChR clusters. Together both agrin and laminin enhance the interaction of the integrin with AChRs and their aggregation into clusters. To further understand this mechanism we investigated cluster formation and the association of the alpha7beta1 integrin and AChR over time following induction with laminin and/or agrin. Our results show that the alpha7beta1 integrin associates with AChRs early during the formation of the post-synaptic membrane and that laminin modulates this recruitment. Laminin induces a rapid stable association of the integrin and AChRs and this association is independent of clustering. In addition to laminin-1, merosin (laminin-2/4) is present both before and after formation of neuromuscular junctions and also promotes AChR clustering and colocalization with the integrin as well as synergism with agrin. Using site directed mutagenesis we demonstrate that a tyrosine residue in the cytoplasmic domain of both (&agr;)7A and (&agr;)7B chains regulates the localization of the integrin with AChR clusters. We also provide evidence that laminin, through its association with the alpha7beta1 integrin, reduces by 20-fold the concentration of agrin required to promote AChR clustering and accelerates the formation of clusters. Thus laminin, agrin and the alpha7beta1 integrin act in a concerted manner early in the development of the post-synaptic membrane, with laminin priming newly formed myofibers to rapidly and vigorously respond to low concentrations of neural agrin produced by innervating motor neurons.
Pharmacological Relapse Prevention of Alcoholism: Clinical Predictors of Outcome

Objective: The efficacy of pharmacological relapse prevention in alcoholism with acamprosate and naltrexone has been supported by several controlled trials. It remains uncertain whether any differential indication for treatment exists. Methods: We evaluated outcome data of a controlled trial on acamprosate and naltrexone in patients with low vs. high baseline somatic distress, depression and anxiety (Symptom Checklist-90, SCL-90), low vs. high baseline craving, and according to typological differentiation as proposed by Cloninger and Lesch. These variables have previously been suggested to be predictors of outcome. Results: Comparing the course of abstinence rates, acamprosate was mainly efficacious in patients with low baseline somatic distress, whereas naltrexone was effective especially in patients with high baseline depression. Baseline craving showed no predictive value. Pharmacological treatment was efficacious in type II alcoholics according to Cloninger. Applying Lesch’s typological differentiation, acamprosate was shown to be mainly effective in type I, whereas naltrexone revealed best treatment effects in type III and IV. Conclusion: The study supports the hypothesis that different subgroups of alcohol dependent subjects might benefit from a differential treatment with either naltrexone or acamprosate. Baseline psychopathology and especially typological differentiation might be useful in matching patients to distinct pharmacotherapeutic interventions.
Prediction of biological functions by histone modification patterns profiling

Histone modifications provide an important layer of gene regulation in eukaryotes. In this paper, we propose an approach that identifies the histone modification patterns most relevant for specific biological functions, such as flowering in plants. We first propose a new pattern scoring method, which evaluates the importance of each combinatorial pattern of histone modifications; this is used along with logistic regression, Support Vector Machines, and naive Bayesian classifier algorithms to predict gene functions. This approach is shown to be successful in inferring significant patterns verified by independent gene function data, outperforming other pattern scores used in current histone modification analysis research. keywords: Histone modification, gene expression, predicting biological function
Efficacy of a National Cholesterol Education Program Step 2 diet in normolipidemic and hypercholesterolemic middle-aged and elderly men and women.

We tested the effects of a National Cholesterol Education Program (NCEP) Step 2 diet (30% of calories or less as total fat, less than 7% saturated fat, and less than 200 mg cholesterol per day) on plasma lipid levels in normocholesterolemic and hypercholesterolemic middle-aged and elderly men and women. Thirty-two subjects were studied. Eight normolipidemic subjects (6 men and 2 women, mean age 56 +/- 13 years) with LDL cholesterol levels of less than 4.14 mmol/L (160 mg/dL) were given a baseline diet similar in composition to the diet currently consumed in the United States (35% of calories as total fat and 14% as saturated fat, with 147 mg cholesterol per 1000 kcal) for 6 weeks. Subjects were then placed on an NCEP Step 2 diet (26% total fat, 4% saturated fat, 45 mg cholesterol per 1000 kcal) for 24 weeks. In addition, 24 subjects (12 men and 12 women, mean age 62 +/- 12 years) with moderate hypercholesterolemia (LDL cholesterol levels of 4.14 mmol/L or above) were given a baseline diet for 6 weeks and then the NCEP Step 2 diet for 6 weeks. Energy intakes were adjusted to keep body weight constant throughout the study. In both normolipidemic and hypercholesterolemic subjects, consumption of the NCEP Step 2 diet was associated with significant changes in levels of total cholesterol (-20% and -16%, respectively), LDL cholesterol (-21% and -18%, respectively), and HDL cholesterol (-16% and -15%, respectively). (ABSTRACT TRUNCATED AT 250 WORDS)
Learning for and from the city : the role of education in urban social cohesion

Learning is a central factor of social and spatial cohesion. Educational institutions play a significant role in the reproduction or transformation of social relations by conveying values and practices that either sustain or contradict the dominant societal structures. Learning is also crucial for the enhancement of urban governance, insofar as it is associated with the promotion of critical thinking, access to information and participation in collective decision-making processes. This article discusses how education contributes to inclusive urban development and local collective identities through the responses it provides to three issues – innovation and creativity, citizenship, and cultural diversity – that have become crucial challenges to urban social cohesion. The last section aims to materialise this discussion around two concrete urban processes : the development of local learning communities – learning from the city ; and the role of educational institutions in socially inclusive urban regeneration processes – learning for the city.
Data Mining on Romanian Stock Market Using Neural Networks for Price Prediction

Predicting future prices by using time series forecasting models has become a relevant trading strategy for most stock market players. Intuition and speculation are no longer reliable as many new trading strategies based on artificial intelligence emerge. Data mining represents a good source of information, as it ensures data processing in a convenient manner. Neural networks are considered useful prediction models when designing forecasting strategies. In this paper we present a series of neural networks designed for stock exchange rates forecasting applied on three Romanian stocks traded on the Bucharest Stock Exchange (BSE). A multistep ahead strategy was used in order to predict short-time price fluctuations. Later, the findings of our study can be integrated with an intelligent multi-agent system model which uses data mining and data stream processing techniques for helping users in the decision making process of buying or selling stocks.
Efficient Computation of Unconditional Error Rate Estimators for Learning Algorithms and an Application to a Biomedical Data

We derive an unbiased variance estimator for re-sampling procedures using the fact that those procedures are incomplete U-statistics. Our approach is based on careful examination of the combinatorics governing the covariances between re-sampling iterations. We establish such an unbiased variance estimator for the special case of K-Fold cross-validation. This estimator exists as soon as new observations are added to the original sample, and we specify how many additional observations are necessary. Thus we make re-sampling procedures comparable. We make no assumptions on the underlying distribution and we take the covariances between re-sampling iterations into account. Beyond that we show an approach to find a re-sampling design with minimal variance for a fixed size of learning sets. We empirically show the existence of designs with smaller variance than repeated cross-validation. We systemically compare with the complete U-statistic, the leave-p-out estimator. Our examination is completed by an application to micro-array data.