Miracle-dz/UniFAR-FTUs huggingface dataset:
Molecular cloning and expression of two b-defensin and two mucin genes in common carp ( Cyprinus carpio L . ) and their up-regulation after b-glucan feeding

In this study, we described the partial structure, mRNA tissue distribution and regulation of two carp mucin and two b-defensin genes. This is the first description of these genes in fish. The genes might provide relevant tools to monitor feed-related improvements of fish health under aquaculture conditions. Carp mucin 2 and mucin 5B genes show a high similarity to their mammalian and avian counterparts. The carp b-defensin 1 and b-defensin 2 genes cluster together well with their piscine family members. The influence of a b-glucan immunomodulant on the expression of these genes in mucosal tissues could be confirmed for the first time. Muc5B expression was significantly increased in the skin. For Muc2 no significant upor down-regulation could be observed. Significantly higher expression levels of b-defensin 2 in gills and both b-defensin genes in skin were found. Thus, the mucosal system can be influenced by the addition of b-glucans to the food. 2011 Elsevier Ltd. All rights reserved.
Early cancer in achalasia.

UNLABELLED Esophagus achalasia is considered by many authors a preneoplasic disease and, for this reason, they propose a follow-up with endoscopies and brush cytology. For others, the possibility of cancer in achalasia is very low and the surveillance is not justified owing to its fallibility and high cost. Generally, cancer in achalasia has a late diagnosis as a consequence of megaesophagus and of many years of symptoms attributed to achalasia disease. The rate of resectability is low and 5-year survival is very poor. To define the patients who have a high disease. The rate of resectability is low and 5-year survival is very poor. To define the patients who have a high risk of cancer in achalasia and to perform an early diagnosis is the challenge to improve resectability and to increase survival. The search of cancer in achalasia with endoscopies and lugol vital staining was performed in 18 out of 76 patients with achalasia. The 18 patients had enlarged esophagus and more than 10 years of evolution. Lugol negative endoscopic areas were found in 10 out of 18 patients and four out of 10 were carcinomas. Two were circular superficial erosive lesions (Tis N0 M0 and T1 N0 M0), one was an elevated multifocal lesion of less than 1 cm diameter (T2 N0 M0) and the last one was a longitudinal central ulcer of less than 1 cm diameter (T1 N0 M0). In the remaining 6 out of 10 patients the diagnosis was esophagitis. In the other 58 patients, three carcinomas were diagnosed, two advanced tumors, with endoscopy and biopsy (T3 and T4 N1) and the third one (T1 N0 M0) was a pathological finding in a resected specimen for recurrent achalasia and megaesophagus. The global prevalence was of 9.21% (7/76). The prevalence in advanced stages of achalasia was of 18.92% (7/37). The resectability rate was of 85.71%. CONCLUSION Achalasia patients with more than 20 years of evolution, enlarged esophagus with 'knees' and with marked retention must be considered to be of high risk for developing cancer. In this group, the surveillance with endoscopy and lugol vital staining or brush cytology is justified. Other common risk factors of esophageal cancer that must be considered are patients aged over 60 years who are smokers and regular consumers of alcohol.
A Systemized Aggregation with Generative Growth Mechanism in Solar Environment

The paper demonstrates a work-in-progress research on an agent-based aggregation model for architectural applications with a system of assembly based on environmental data acted as a driver for a growth mechanism. Even though the generative design and algorithms have been widely employed in the field of art and architecture, such applications tend to stay in morphological explorations. This paper examines an aggregation model based on Diffusion Limited Aggregation system incorporating solar environment analysis for global perspective of aggregation, the geometry research for lattice systems, and morphological principles of unit module in agent scale. The later part of this research paper demonstrates the potential of a design process through the “Constructed Cloud” case study, including site-specific applications and the implementation of the systematized rule set.
Myotonia dystrophica and spinal surgery

Two cases of patients suffering from the congenital form of myotonia dystrophica under going spinal surgery are presented. Both patients had major complications, including cardiac arrhythmias, postoperative wound infection and more minor complications, such as sedation and opioid sensitivity. However, the most notable complication resulting in long‐term morbidity was the deterioration of bulbar muscular function in one of the patients. This resulted in recurrent aspiration pneumonia and the need for a tracheostomy. This serious complication has not previously been reported following surgery.
Champ 7 Prise en charge hémodynamique du syndrome de détresse respiratoire aiguë Hemodynamic management of acute respiratory distress syndrome

La connaissance de l’état cardiocirculatoire des malades développant un syndrome de détresse respiratoire aiguë (SDRA) constitue un élément clef de leur prise en charge. L’insuffisance circulatoire aiguë (ICA) est en effet fréquente au cours du SDRA et son impact sur le pronostic des malades est majeur. Les raisons de cette ICA sont multiples, souvent intriquées, et nécessitent une prise en charge thérapeutique hémodynamique mais souvent aussi ventilatoire, en adaptant les paramètres du respirateur à la fonction ventriculaire droite.
QUALITATIVE SPATIAL REASONING BASED ON ALGEBRAIC TOPOLOGY

Several formalisms have been proposed for qualitative reasoning about regions and their topological relations in space. These formalisms, based on pairwise relations, do not allow sufficiently powerful inferences to be used for spatial reasoning tasks such as planning a collision-free path. In this paper, I show how considering relations between region triples, much more powerful reasoning techniques become possible. I show in particular that in two dimensions, purely topological reasoning is sufficient to compute a minimal place graph which represents all minimal and maximal region combinations, as well as all minimal paths between them. I illustrate how this could be applied to motion planning, showing that in spite of its qualitative nature, the formalism is powerful enough to solve problems of practical interest.
Application of Delphi method for Criteria prioritization in hazardous waste landfill site selection in Iran

The disposal is the final step of any hazardous waste management plan. Convenient Landfill Site Selection depends on various criteria. This study sought expert consensus in a 2-round Delphi survey to rate the importance of environmental criteria for hazardous waste landfill site selection in Salafchegan-Iran. A group of 17 experts rated the importance of 14 criteria. Consensus was reached on all 14 criteria (Standard Deviation for all criteria was less than 2.00 and the Mode of answers was considered as consensus). Keywords—Delphi method; site selection criteria; hazardous waste landfill
Voltammetry as a tool for monitoring micellar structural evolution?

Self-assembled systems such as micelles and liquid crystals are currently of interest as templates for the controlled formation of nanoscale structures. Knowledge of the mesophase structure, structural evolution, and interparticle interaction is of great importance in understanding the behavior of such systems especially for applications such as nanoreactors. Here, we compare the use of cyclic voltammetry, chronoamperometry, and the rotating disk electrode (RDE) for the determination of micellar hydrodynamic radii and show that only the steady-state RDE yields values directly comparable with nonelectrochemical techniques. The RDE is applied for the determination of cetyltrimethylammonium chloride micellar structure and observing micellar structural evolution as well as evaluating the usual intermicellar interactions. The results clearly show (a) the collapse of the micellar shear plane toward the hard-sphere surface with increasing electrolyte concentration, (b) the electrolyte-dependent spherical expansion of the micellar hard-spheres due to increasing aggregation (N) number, (c) the structural transition from spherical to rodlike micelles, and (d) micellar elongation. As well as structural evolution, the evolutionary changes in interaction processes are also observed, i.e. the transition from Coulombic interactions to excluded volume interaction. This paper describes in detail the voltammetric measurement of these processes and explicates the necessary experimental conditions for successful observation of micellar structural evolution.
Opinion on risk to health from fruit and vegetables and their products grown in areas where cholera ( Vibrio cholerae ) has reached epidemic levels ( expressed on 4 June 1998 ) Terms of reference

The Commission has recently introduced safeguard measures through Commission Decision 98/116/EC Commission Decision of 4 February 1998 adopting special measures for the import of fruit and vegetables originating in or consigned from Uganda, Kenya, Tanzania, and Mozambique. Official journal No. L 31, 06/02/1998, p. 28-29) adopting special measures for the import of fruit and vegetables originating in or consigned from Uganda, Kenya, Tanzania, and Mozambique due to a cholera epidemic in these countries under the article 10 of the hygiene of foodstuffs directive 93/43/EEC (Council Directive 93/43/EEC of 14 June 1993 on the hygiene of foodstuffs. Official journal No. L 175, 19/07/1993, p.1-11).
EFFICIENT NEURAL NETWORK MODELING BASED ON DATAFLOW COMPUTING LANGUAGES

We present an efficient dataflow modeling of Multilayer Perceptron (MLP) algorithm based on the directed graph concept but with controlled global states. More specifically, we investigate the dataflow implementation of two efficient and widely used MLP training algorithms, namely, on-line Backpropagation and Conjugate Gradient in its major versions. The proposed MLP dataflow modeling approach is applied to a medical diagnosis problem, namely, psychiatric case categorization based on evoked potential data classification. The whole system is implemented in the Labview-G programming environment and it is found that the modeling capabilities along with the results obtained from the proposed MLP dataflow implementation in G demonstrate its efficiency for medical diagnosis applications.
A Living HCI Curriculum

This panel seeks to further explore among multiple diverse HCI educators and researchers on how to proceed with the establishment of an HCI living curriculum that integrates different cultural contexts and requirements from the bottom up, in an emic way. The panelists will focus particularly on their own perspectives in relation to the indigenous appropriation of the HCI curriculum not only in Africa but in the Global South. The main goal of the panel is to generate a discussion around opportunities and challenges in the co-design and innovation of a locally meaningful HCI curricula.
Modeling Automated Inspection Plans for Straight Line Detection in Image Scenes

This article explains an approach to further enhance the detection of geometric primitives namely straight lines, based on the spline filter contour decomposition method as shown in [1]. The aim is to split complex features into simple primitives for which further processing steps will lead to automated measurement results. Thus the inspection plan generated is reusable without employing additional CAD software tools. The feature recognition approach proposed in this paper incorporates an adaptive spline filter scale space method for smoothing contour point clouds at subpixel-scale precision with the aim to reduce the user influence on the setup of ROIs (regions of interest) in image scenes and therefore increasing usability of software interfaces.
Should People with Disabilities Work in Their Communities ? Or do they earn more from governmental subsidies ?

Prior to the 1970s, many people doubted that individuals with disabilities were capable of working. Throughout the 1980s and 1990s, study after study found that not only can individuals with disabilities perform meaningful vocational tasks, but that they also prefer competitive employment to sheltered workshops. However, twenty years later, many people still insist that, while individuals with disabilities can and want to work, they shouldn’t do so because they will lose their government benefits and end up with less money than they would have received had they not worked at all. Several recent studies have explored this issue.
ASYMPTOTIC BEHAVIOR OF THE SIXTH-ORDER BOUSSINESQ EQUATION WITH FOURTH-ORDER DISPERSION TERM

In this article, we investigate the initial-value problem for the sixth-order Boussinesq equation with fourth order dispersion term. Existence of a a global solution and asymptotic behavior in Morrey spaces are established under suitable conditions. The proof is mainly based on the decay properties of the solutions operator in Morrey spaces and the contraction mapping principle.
Two-tier Geiger-mode avalanche detector for charged particle imaging

In this contribution, we present the first demonstration of a new type of silicon sensor for the direct detection of charged particles. The proposed device, based on 3D-integrated Geiger-mode avalanche diodes, features early signal digitization, sub-nanosecond timing and low material budget. The Dark Count Rate is dramatically reduced thanks to the coincidence between two vertically-integrated layers. A preliminary demonstration of sensor operation in the dark and in the presence of charged particles is presented. INTRODUCTION Sensors based on Single Photon Avalanche Diodes (SPAD) are currently expanding from niche markets to consumer electronics thanks to their possibility of being CMOS integrated. Their picosecond timing resolution and intrinsic amplification characteristics are the key to low-power fast optical sensors with excellent Signal to Noise ratio [1]. Research on new architectures and 3D integration possibilities are making them more and more applicable in a variety of optical sensing applications [2]. In this work, we demonstrate a CMOS-integrated sensor based on Geiger-mode avalanche diodes for the direct detection of charged particles. The proposed device, formed by two vertically-aligned pixelated detectors, exploits the coincidence between two simultaneous avalanche events to discriminate between particle-triggered detections and dark counts (Figure 1) [3]. This approach offers several advantages in applications requiring low material budget and fine detector segmentation as, for instance, for tracking and vertex reconstruction in particle physics experiments and charged particle imaging in medicine and biology. SENSOR DESIGN A two-tier sensor assembly was designed and fabricated in a commercial 0. 15μm CMOS process. The sensor consists of a 48x16 pixel array, and includes avalanche diodes of different sizes and types [4]. Each pixel, having a 50μm x 75μm area, includes detectors and electronics on both layers, with the top-layer signal transmitted to the bottom layer using a vertical interconnection per pixel (Figure 2). Bump bonding technique using 12-μm solder bumps was adopted for the vertical integration. The detectors were covered with a metal shield to avoid inter-layer optical cross-talk. The schematic diagram of a 2-level pixel is shown in Figure 3. In the pixel, the detectors are passively quenched and their output signals are digitized by means of a low-threshold comparator. The resulting pulses are shortened by a programmable-length monostable circuit. The pixels can be independently enabled or disabled with an arbitrary pattern, defined by a configuration register. The output of the monostable in the top half-pixel feeds a coincidence detector located in the bottom layer, and the
The hazards of hazard ratios.

T he hazard ratio (HR) is the main, and often the only, effect measure reported in many epidemiologic studies. For dichotomous, non–time-varying exposures, the HR is deﬁned as the hazard in the exposed groups divided by the hazard in the unexposed groups. For all practical purposes, hazards can be thought of as incidence rates and thus the HR can be roughly interpreted as the incidence rate ratio. The HR is commonly and conveniently estimated via a Cox proportional hazards model, which can include potential confounders as covariates. I review 2 problems and some proposed solutions. As I will use the from a Initiative randomized experiment compared the risk of heart disease of women assigned to combined (estrogen plus progestin) hormone therapy with that of women assigned to placebo. 1 By using a randomized experiment as an example, the discussion can focus on the shortcomings of the HR, setting aside issues of confounding and other serious problems that arise in observational studies.
Weighing In

As the accountability movement has gained momentum, policy makers and educators have strived to strike a difficult balance between the sometimes competing demands at the local, state, and federal levels. Efforts to improve accountability and teacher evaluation have taken an especially unique route in Iowa, where local control and resistance to state mandated curricular standards have been popular topics from the statehouse to the convenience store. This research explores principals’ impressions of Iowa’s state-mandated standards for best-practice teaching (as opposed to state mandated curricular standards). Further, the research examined the extent to which the Iowa Teaching Standards (ITS) and accompanying Iowa Evaluator Approval Training Program (IEATP) have impacted the way teacher evaluations are conducted in the state’s rural schools. Evidence indicates that most principals felt that ITS and the accompanying IEATP made them feel adequately or very well prepared to conduct teacher evaluations. In addition, 65% of respondents reported that IAETP had changed the way teachers are evaluated.
Dynamic Investigation on Proton Exchange Membrane Fuel Cell Systems

Nowadays, the most common fuel cell type is the low temperature proton exchange membrane (PEM) fuel cell. This paper investigated the dynamic behaviour of proton exchange membrane fuel cells working as an autonomous power generator. The described system model includes a PEM fuel cell voltage model with regards to the dynamic limitations of the fuel cell stack and a logistical model for the battery storage. With this system model it is possible to investigate autonomous fuel cell systems, prior to construction, for different dynamic load demand characteristics. The work presented in this paper was done by the authors at the fuel cell lab of the Otto-von-Guericke-University Magdeburg.
Abdominal ve torakal aort anevrizmalarında endovasküler stent greft uygulaması Endovascular stent graft repair of abdominal and thoracic aortic aneurysms

Atrial fibrillation (AF) is one of the most common postoperative arrhythmias in patients who undergo coronary artery bypass grafting (1). This complication leads to increases in mortality and morbidity rate in coronary bypass surgery and in hospital stay caused by excess usage of medications (2). Diverse experimental and clinical trials are conducted to reduce post-operative AF development rate and associated complications; however, AF rate still remains to be up to 40% during bypass surgery. The etiology of postoperative AF is not well defined, although recent studies suggest a multi-factorial mechanism, which includes oxidative stress, inflammation, atrial fibrosis, and excessive production of catecholamines, changes in autonomic tone and in the expression of connexins (3, 4). By evaluating retrospectively our coronary bypass surgery results, we observed that we did not discontinue preoperatively used anti-aggregants since a long time and that postoperative AF rate was lower than found in coronary literature. At Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Training and Research Hospital coronary artery bypass surgeries that are performed by the same clinic between January 2009 and December 2009 were reviewed retrospectively. Statistical analysis is made by SPSS 15. Stopping anti-aggregants therapy before coronary bypass surgery is a classical literature knowledge; therefore control group parameters are taken from the literature ratios. Atrial fibrillation development rate was retrospectively evaluated in 250 coronary bypass patients who used anti-aggregants and also not discontinued before the operation. There was no significant difference between selected patients in terms of clinical and laboratory examinations. There was no atrial fibrillation history in all patients. There was no significant difference in duration of operation and number of used graft. LIMA and saphenous vein were used as graft in all patients. Atrial diameter of patients was similar and they had no atrial dilatation. Atrial fibrillation was developed in 9 patients (3%). According to literature information (3, 4), atrial fibrillation rate was assessed very low. In the controls after two months; there was no statistically significant increase in AF ratio. There was no significant increase in postoperative administration of blood or blood derivative considered as side effects despite to continuation of anti-aggregant usage. Revision and tamponade rate due to bleeding was conforming to literature. Continuing to preoperative anti-aggregant in patients without AF development risk factors significantly reduces AF development rate and we conclude that this may be considered as our coronary experience of a wide serial.
Methodology for enumeration of coliphages in foods

The effects of eluent composition, pH, and chaotropic agents on the recovery of T2, MS2, and indigenous coliphages from various foods were investigated. Additionally, methods of sample suspension and clarification were evaluated for coliphage recovery and application to various foods. Clarified sample suspensions were assayed for coliphages with a modified agar layer technique and appropriate Escherichia coli hosts. Centrifugation and polypropylene mesh filtration were more rapid and effective than glass wool filtration for clarification of sample suspensions and subsequent recovery of coliphages. Blending, stomaching, and shaking procedures were generally comparable for sample liquefaction and release of coliphages from foods. Complex basal eluents, EC medium and 1% casein, were generally more effective than a less complex eluent, phosphate buffer, for elution of coliphages from foods. For most foods, incorporation of sodium chloride or chaotropic agents, i.e., sodium trichloroacetate, urea, Tween 80, Triton X-100, and sodium nitrate, into basal eluents did not enhance recovery of coliphages. Indigenous coliphage recovery was not affected by sample suspension pH over a range of 6.0 to 9.0. With an optimal procedure, i.e., EC medium eluent, blending, and centrifugation, the recovery of T2 and MS2 ranged from 48 to 81% and from 58 to 100%, respectively, depending on the food type.