Miracle-dz/UniFAR-FTUs huggingface dataset:
V-Flow: Deep Unsupervised Volumetric Next Frame Prediction

—Predicting the temporal dynamics of three-dimensional images is an important means for analyzing volumetric data. We propose an unsupervised learning of a multi-scale optical ﬂow based approach for predicting the next frame of a sequence of volumetric images. The fully differentiable model consists of speciﬁc crafted modules that are trained on small patches. To test the proposed approach, we ran unsupervised experiments on synthetic incompressible two-ﬂuid Navier-Stokes simulation and real magnetic resonance imaging (MRI) of the cardiac cycle. Comparison of a spatial version of our architecture to recent methods in predicting the next frame of movie sequences shows signiﬁcant quantitative and visual improvements.
Will the hydrogen therapy be approved shortly?

Department of Neurology Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan Correspondence to: Shigeo Ohta. Juntendo University Graduate School of Medicine. Department of Neurology Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan. Email: ohta@nms.ac. jp. Provenance and Peer Review: This article was commissioned by the Editorial Office, Annals of Translational Medicine. The article did not undergo external peer review. Comment on: Malý O, Zajak J, Hyšpler R, et al. Inhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection. Ann Transl Med 2019;7:774.
INFLUENZA A (H1N1): REVISÃO BIBLIOGRÁFICA

A influenza A e uma doenca causada pelo virus H1N1, um virus RNA fita simples que sofre varias mutacoes genicas favorecendo o aparecimento de varios subtipos desse virus. A transmissao desse virus e de pessoa para pessoa, por meio da inalacao de goticulas respiratorias contendo as particulas virais infectantes. Os principais sintomas apresentados decorrentes da infeccao sao febre alta, dor muscular, dor de cabeca, tosse e cansaco. O diagnostico se baseia na cultura a partir do isolamento do virus em secrecoes faringeas e nasais, testes sorologicos, deteccao de antigenos virais e reacao de cadeia de polimerase (PCR). O principal tratamento se baseia na utilizacao de antivirais e a principal forma de prevencao sao as vacinas, distribuidas nas campanhas de vacinacao. O objetivo dessa revisao e abordar a influenza A nos seguintes aspectos: sintomas, agente etiologico, complicacoes, tratamento, expondo tambem a situacao epidemiologica no Brasil no ano de 2016. As informacoes contidas neste estudo foram obtidas em bases de dados virtuais, tais como PubMed, MEDLINE, SciELO. De acordo com os dados obtidos, foi possivel perceber um aumento no numero de casos e de obitos decorrentes de influenza A durante as 21 primeiras semanas de 2016. INFLUENZA A (H1N1): BIBLIOGRAPHIC REVIEW ABSTRACT Influenza A is a disease caused by the H1N1 virus, a single-stranded RNA virus that undergoes multiple gene mutations favoring the appearance of several subtypes of this virus. Transmission of this virus is from person to person, by inhalation of respiratory droplets containing the infectious viral particles. The main symptoms presented by the infection are high fever, muscle pain, headache, cough and tiredness. Diagnoses are based on culture from virus isolation in pharyngeal and nasal secretions, serological tests, detection of viral antigens and polymerase chain reaction (PCR). The main treatment is based on the use of antivirals and the main form of prevention is the vaccine, distributed in the vaccination campaigns. The aim of this review is to discourse about influenza A in the following aspects: symptoms, etiologic agent, complications, treatment, and also the epidemiological situation in Brazil in the year 2016. The information contained in this study was obtained from databases such as PubMed , MEDLINE, SciELO. According to the data obtained, it was possible to notice an increase in the number of cases and deaths due to influenza A during the first 21 weeks of 2016.
TENDERNESS AND SENSORY ATTRIBUTES OF ELEVEN MUSCLES FROM CARCASSES WITHIN THE CANADIAN MATURE BEEF GRADES

Meat from mature cattle carcasses is often tough, therefore meat from these animals is usually not suitable for sale in retail and may be used in further processed products. The aim of the present study was to determine which muscles from carcasses graded within the Canadian grading standards for mature carcasses have similar eating quality to youthful beef. While the majority of muscles were perceived to be less tender, other sensory characteristics such as juiciness and beef flavour were generally similar, or in some cases better than youthful beef. These data indicate some opportunities exist for improved utilization of cow meat and provide grade and muscle specific guidance to improve eating quality.
The distribution planning process in a supply chain with multiple transportation strategies

This paper compares different approaches to solve the distribution planning process problem with distribution strategy choice in supply chains, encompassing several production plants and several regional warehouses that fulfill a set of retail customers with several references. The problem has been tackled considering two different perspectives: the former is more empirical, providing a heuristic solution (Empirical model) of the problem, while the latter is based on a mixed integer linear programming model (Analytical model). The paper discusses the computational results obtained by applying the aforementioned approaches in terms of costs, optimality gap and computational time to the food supply chain of an Italian subsidiary of a German group encompassing 2 production plants located in Germany, 2 regional warehouses situated in Italy, that fulfill 200 retail customers with 19 references. In addition to the computational results that provide a comparison among the solution applied by the company (Rule of thumb), the Empirical model and the Analytical model, managerial insights are underlined, in terms of applicability of the best approach within the specific company context.
To look or not to look during vaccination: A pilot randomized trial

ABSTRACT Background Clinicians commonly advise patients to look away from the needle during vaccinations; however, this recommendation is not evidence based. Aim The aim of this study was to determine whether looking at the needle versus looking away affects pain and fear during vaccinations in adults. Methods This was a pilot randomized two-group parallel trial with university students receiving influenza vaccinations. Participants were stratified according to their initial needle-looking preference and randomly assigned to either look at versus away from the needle. Participants self-reported their pain and fear during vaccination. Results Of the 184 subjects who agreed to participate, 160 were enrolled; 66% were female. A three-way analysis of variance (ANOVA; Looking allocation assignment × Looking preference × Sex) revealed a significant main effect of looking allocation assignment on fear (P = 0.025); those who were randomized to look had higher fear scores than those who were randomized to look away. There was also a significant main effect of looking preference on fear (P < 0.001); those who preferred to look away had higher fear scores than those who preferred to look. There was no evidence of an effect of looking allocation assignment or looking preference on pain. There was a significant main effect of sex on fear and pain, with females reporting higher pain and fear scores than males (P = 0.017 and P = 0.001, respectively). There were no significant interactions. Conclusion These preliminary findings suggest that advising individuals to look away from the needle reduces fear. A larger trial including more individuals and a different population is recommended to confirm the results.
THE COMMONALITIES BETWEEN THE ASIAN FINANCIAL CRISIS OF 1997 AND THE CURRENT BANKING CRISIS OF VIETNAM AND IMPLICATIONS FOR THE FUTURE by

This paper revisits the East Asian financial crisis of 1997 through reexamining how imprudent lending and poor credit risk management devastated the financial systems of many emerging countries in East Asia. The paper also explores the state-controlled banking system of China and Vietnam, the two countries least affected by the events of 97. Incompetency and inefficiency, due to non-competitive environment, in banks’ operation of these two countries are also addressed. Vietnam, in particular, has recently experienced a banking crisis in which it has repeated the very same mistake that caused the crisis of 1997 regarding credit risk management. This paper proposes potential solutions, some of which has already been undertaken by the Vietnamese authority, to improve the overall health of the banking system and prevent future occurrence. Unsurprisingly, the government and the State Bank play a critical role.
Role of Information Systems for Strategic Agility in Supply Chain Setting: Telecommunication Industry Study

: The ability of a company to either adapt to the changes in the business environment or to influence the environment, for example by innovations, determines its success in gaining competitive advantage or even survival in the contemporary business environment. Both scholars and practitioners are constantly devising ways to survive the environmental pressures, such as, information overload, technological advances and obsolescence and globalization. This research proposes strategic agility comprised of strategic sensitivity, strategic response and collective capabilities as one such business virtue required. One such competitive and complex industry is Telecommunication industry and this study makes use of a company in that industry to investigate strategic agility and information systems (IS) role in promoting strategic agility. In addition, the supply chain setting is considered because of its significance in the industry as one of the competitive factors. The research revealed different points of view for the role of IS from business and information technology (IT) managers. The value of strategic agility is appreciated by both sets of managers. However, the managers have different views on the value of IS in promoting the strategic agility dimensions, for instance, most business managers highlighted that IS is of no strategic value and one even claimed it is the worst performing function. But IS managers noted that, IS, for instance , business intelligence and enterprise resource planning systems could be utilized hand-in-hand to support strategic agility. Moreover, this study make use of dynamic capabilities view in drawing both strategic agility dimensions and IS input. This study contributes to the ever required knowledge on how business could make use of IS and adapt organizational features to the environment requirements in order to survive the competition.
The Use of Nanotechnology in Cosmetic Formulations: The Influence of Vehicle in the Vitamin A Skin Penetration

Topical photodynamic therapy (PDT) has been applied to almost all types of nonmelanoma skin cancer and numerous superficial benign skin disorders. Strategies to improve the accumulation of photosensitizer in the skin have been studied in recent years. Although the hydrophilic phthalocyanine zinc compound, zinc phthalocyanine tetrasulfonate (ZnPcSO4) has shown high photodynamic efficiency and reduced phototoxic side effects in the treatment of brain tumors and eye conditions, its use in topical skin treatment is currently limited by its poor skin penetration. In this study, nanodispersions of monoolein (MO)-based liquid crystalline phases were studied for their ability to increase ZnPcSO4 uptake by the skin. Lamellar, hexagonal and cubic crystalline phases were prepared and identified by polarizing light microscopy, and the nanodispersions were analyzed by dynamic light scattering. In vitro skin penetration studies were performed using a Franz's cell apparatus, and the skin uptake was evaluated in vivo in hairless mice. Aqueous dispersions of cubic and hexagonal phases showed particles of nanometer size, approximately 224 ±10 nm and 188 ± 10 nm, respectively. In vitro skin retention experiments revealed higher fluorescence from the ZnPcSO4 in deeper skin layers when this photosensitizer was loaded in the hexagonal nanodispersion system when compared to both the cubic phase nanoparticles and the bulk crystalline phases (lamellar, cubic and hexagonal). The hexagonal nanodispersion showed a similar penetration behavior in animal tests. These results are important findings, suggesting the development of MO liquid crystal nanodispersions as potential delivery systems to enhance the efficacy of topical PDT.
Defense against Routing Disruption Attacks in Mobile Ad Hoc Networks

We propose a secure routing architecture for Mobile Ad hoc NETworks (MANETs) called ThroughpUt-Feedback (TUF) routing, which is resilient against a wide range of routing disruption Denial-of-Service (DoS) attacks. Unlike many existing solutions, TUF does not focus on a particular type of attack, but instead takes an approach that is fundamentally more general. TUF is a cross-layer technique that detects attacks at the transport layer but responds to attacks at the network layer. Because most routing disruption attacks cause a significant drop in end-to-end goodput, monitoring the goodput of a route at the transport layer can detect abnormalities in the network (e.g., node or link failures, DoS attacks, etc.). Once an abnormal event is detected, a route rebuilding process is initiated at the network layer to find a new route. Using analysis and simulation results, we show that the TUF architecture is effective in thwarting a wide range of attacks, including protocol-compliant (also known as “JellyFish”) attacks.
Analysis of the File System and Block IO Scheduler for SSD in Performance and Energy Consumption

SSD (Solid State Disk) is reconsidered as the next storage device, an alternative to the HDD (Hard Disk Driver). The read/write performance and energy consumption are main aspects to the users. In our experiment, we recognize that the performance and energy consumption of SSD, based on NAND Flash, are mostly related with the file system and block I/O scheduler. In order to gain higher performance and lower energy consumption, we test the different combination of file system and scheduler under workload simulator, File bench, using three kinds of commercial SSDs. According to the different combination of file system and block I/O, we analyze the performance parameter, IOPS, and energy consumption parameter, POWER, under some special workload. Lastly, we present a parameter, aggregative indicator (AI), to evaluate the overall characteristic of some combination of file system and block I/O, which synthesizes IOPS and POWER. It is to find a better combination for special workload. In the experiment, the combination of extent file system (ext2 or ext3) and CFQ expresses better more value of the aggregative indicator than others.
Performance Analysis of Spatial Modulation Aided NOMA With Full-Duplex Relay

A spatial modulation aided non-orthogonal multiple access with full-duplex relay (SM-NOMA-FDR) scheme is proposed for the coordinated direct and relay transmission in this paper. Specifically, the signal of the near user is mapped to an $M$-ary modulated symbol and the signal of the far user is mapped to an SM symbol. The base station first transmits signals to the near user and relay via SM-NOMA, and then the relay decodes and retransmits the signal of the far user. An SM-assisted FDR is used in this scheme to improve the spectral efficiency while reducing energy consumption and making full use of the antenna resources at the relay, since SM only activates one antenna in each transmission. We derive the ergodic capacity and bit error rate of the proposed scheme over independent Rayleigh fading channels. Numerical results validate the accuracy of the theoretical analysis and show the superior performance of the proposed SM-NOMA-FDR scheme.
CHAOS IN A FRACTIONAL ORDER MAGNETO-FLEXIBLE ROD

The present paper investigates the existence of chaos in a fractional order magneto-flexible rod (FOMFR). This is a system subjected to magnetic forces that can bend it while simultaneously subjected to external excitations produces complex and nonlinear dynamic behavior. The system is analyzed based on numerical simulation involving both, integer order calculus (IOC) and fractional order calculus (FOC) approaches. The time histories and pseudo phase portraits have been presented. Using the maximal Lyapunov exponent criteria based on Wolf’s algorithm, we show that the FOMFR exhibits chaos. The results obtained can be used as a source for conduct others numerical and physical experiments in order to obtain a possible controller design to suppress the chaos of the FOMFR. S. A. David, J. M. Balthazar, B. H. S. Julio, C. Oliveira
Equalization and clock recovery for a 2.5-10-Gb/s 2-PAM/4-PAM backplane transceiver cell

A folded multitap transmitter equalizer and multitap receiver equalizer counteract the losses and reflections present in the backplane environment. A flexible 2-PAM/4-PAM clock data recovery circuit uses select transitions for receive clock recovery. Bit-error rate less than 10/sup -15/ and power equal to 40 mW/Gb/s has been measured when operating over a 20-in backplane with two connectors at 10 Gb/s.
MEAT THE FUTURE

When I was given the opportunity to take the podium at last year’s WTO-public forum in Geneva, I raised the issue of crisis management and the necessity of coming together, more efficiently and much faster than the usual worldwide procedure. I repeated it in a Civil Dialogue Group in Brussels this January, although I have to admit that at the time, I was actually thinking about a solution for the African Swine Fever. Today, the Coronavirus puts the world in a completely new and serious situation that hardly anyone could have predicted.
Footloose multinational and the effects of domestic cost efficiency

We show that cost efficiency in the domestic industry may reduce domestic welfare if it changes foreign firm’s production strategy from foreign investment to export. We find that domestic cost efficiency is welfare reducing only if the domestic market size is sufficiently small and the domestic firm’s cost of production is higher compared to the foreign firm’s cost of production under foreign investment.
The Diagnostic and Prognostic Value of Mitral Annular Plane Systolic Excursion (MAPSE) as an Echocardiographic Indicator of Myocardial Dysfunction in Sepsis and Septic Shock

Objectives: Validation of mitral annular plane systolic excursion (MAPSE) as a rapid easy marker of left ventricle (LV) systolic function in general, and as an independent predictor of systolic function and mortality among patients with septic shock. Background: Sepsis-induced myocardial dysfunction is one of the major predictors of morbidity and mortality in sepsis. Cardiac ultrasonography has become an indispensible tool in ICU for management of hemodynamically unstable critically ill patients, and MAPSE has been suggested as a surrogate measurement for LV function. Methods: Prospective analysis of 50 septic shock patients by transthoracic echocardiography was carried out. MAPSE, LV ejection fraction (LVEF) measured by modified Simpson’s method, and Original Research Article Gomaa et al.; AJMAH, 7(2): 1-10, 2017; Article no.AJMAH. 36145 2 mitral annular systolic velocity by tissue Doppler imaging TDI were measured every other day for 1 week, and they were correlated with cardiac injury biomarkers and mortality predictors. Results: MAPSE values correlated significantly with sequential organ failure assessment score (SOFA score) among survived and non-survived patients (average; r – 0.95 with p-value <0.001 and average; r – 0.85 & 0.84 with p-value <0.001 respectively), with high percentage of nonsurvivor group had MAPSE ˂ 9 mm, on the other hand high percentage of survivor group had MAPSE ≥ 9 mm, and regarding receiver operating characteristic (ROC) curves for mortality prediction; MAPSE was (95.5% sensitivity, 67.9% specificity, and 92% accuracy for cut-off value of ≤ 8.8 mm). Also, it was found that there was statistically significant positive correlation with p-value <0.05 between MAPSE with LVEF and systolic mitral annular velocity TDI S' values, with high percentage of LVEF value ≤ 50% had MAPSE ˂ 9 mm and TDI S' ≤ 8 cm/sec, on the other hand high percentage of LVEF value > 50% had MAPSE ≥ 10 mm and TDI S' > 8 cm/sec, and regarding ROC curve for prediction of LVEF of value ≤ 50%; MAPSE measurement was (98.1% sensitivity, 90.9% specificity, and 96.4% accuracy for cut-off value of ≤ 9 mm). Conclusion: MAPSE value is thought to be an independent tool for LV systolic function assessment generally, as well as myocardial injury in patients with sepsis induced myocardial dysfunction, and also a predictor of mortality in patients with severe sepsis and septic shock.
BURNOUT EM ESTUDANTES DA ÁREA DA SAÚDE E RESIDENTES DE MEDICINA - REVISÃO DE LITERATURA

Objetivo: descrever dados publicados sobre a Sindromede Burnout (SB) entre estudantes da area da saudee residentes de medicina no Brasil. As variaveis analisadasneste estudo foram faixa etaria, genero, fatoresdiretamente relacionados a SB, fatores inversamente relacionadosa SB e comorbidades associadas. Metodos:revisao de literatura a partir de consulta a artigos publicadosnas bases de dados Medline, SciELO e Lilacs de janeiro 2007a julho 2015. Foram analisados onze artigos cientificos quecorrespondiam ao objetivo da revisao. Resultados: o numerototal de participantes foi de 3.141 individuos, sendo 61%mulheres. A media de idade foi 24,19 anos. SB foi mais prevalenteno sexo masculino, em jovens, solteiros e sem filhos.Conclusoes: pesquisas sobre Burnout entre estudantes daarea da saude e residentes medicos sao escassas no Brasil e nomundo. Os achados mostram a necessidade de instrumentosmais claros que abordem a relacao entre estresse ocupacionale aspectos psicossociais, considerando a relevância dessesfatores na vida destes profissionais.
Parasites as niche modifiers for the microbiome: A field test with multiple parasites

Parasites can affect and be affected by the host’s microbiome, with consequences for host susceptibility, parasite transmission, and host and parasite fitness. Yet, there are two aspects of the relationship between parasite infection and the host microbiome that remain little understood: the nature of the relationship under field conditions, and how the relationship varies among parasite species. To overcome these limitations, we assayed the within-leaf fungal community in a grass population to investigate how diversity and composition of the fungal microbiome are associated with natural infection by fungal parasites with different feeding strategies. We hypothesized that parasites that more strongly modify niches available within a host will thereby alter the microbial taxa that can colonize the community and be associated with greater changes in microbiome diversity and composition. A parasite that creates necrotic tissue to extract resources (necrotrophs) may act as a particularly strong niche modifier whereas one that does not (biotrophs) may not. Barcoded amplicon sequencing of the fungal ITS region revealed that the microbiome of leaf segments that were symptomatic of necrotrophs had lower fungal diversity and distinct composition compared to segments that were asymptomatic or symptomatic of other parasites. There were no clear differences in fungal diversity or composition between leaf segments that were asymptomatic and segments that were symptomatic of other parasite feeding strategies. This supports the hypothesis that within-host niches link infection by parasites to the host’s microbiome. Together, these results highlight the importance of parasite traits in determining parasite impacts on the host’s microbiome.