Miracle-dz/UniFAR-FTUs huggingface dataset:
Financing Digital Product Companies

Digital product (DP) firms include software developers, e-books, e-newspapers, digital music and movies, and games. Depending on their size and maturity, all firms have a myriad of choices for raising capital and DP firms are no exception. Many DP firms have pursued a strategic growth strategy to take advantage of newly available opportunities like personal computers, electronic mail, the Internet, and electronic commerce. In some instances there have been barriers to introduction because larger successful companies already existed or were already producing a competing product that would dominate and create an all-or-nothing market share environment. There is also a large amount of fixed cost investment for the typical DP firm that must ultimately be recovered. But if the firm is successful, and a critical mass of users reached, potential profits and returns on investment can be very large. However, with growth comes an increasing need for capital. AbstRAct
[Occupational stress in municipal police officers: contribution to the Italian adaptation of a questionnaire for the assessment of the operational and organizational stressors].

INTRODUCTION The study of occupational stress in police has received growing interest because of the potential negative effects that it may produce both on an individual and on an organizational level. The aim of the present research is to give a first contribution to the Italian adaptation of two questionnaires used in order to assess operational and organizational stressors in police: the Operational Police Stress Questionnaire (PSQ-Op) and the Organizational Police Stress Questionnaire (PSQ-Org). METHODS; The PSQ-Op-It and the PSQ-Org-It have been administered to all the municipal police officers serving the population of a small town in Northern Italy (N = 88). An explorative factor analysis has been carried out to verify the internal structure; in order to assess the concurrent validity, correlations with psycho-physical malaise (GHQ-12) and burnout (MBI-GS) have been calculated. RESULTS The factor analysis (rotation method oblimin) confirmed the original structure of the two questionnaires: two factors, corresponding to organizational and operational stressors, have been extracted. The Cronbach's alphas of the two questionnaires, 0.95 and 0.94 respectively, have pointed out good internal consistency. The two instruments are related to the subscales of the GHQ-12 and the MBI-GS, with the exception of the professional inefficacy dimension. CONCLUSIONS The PSQ-Org-It and the PSQ-Op-It have shown good psychometric properties, so they could be used in order to assess police-specific stressors. Nevertheless we suggest to deepen the obtained results by confirmative factor analyses to carry out through the administration of the instrument to more numerous samples, in different and more structured urban contexts.
Towards Multimodal: a Telecom Perspective Keith Waters (Boston

The emerging area of Multimodality can be well demonstrated in the operation of a Telecom. Within France Telecom there are thriving fixline, Internet and mobile businesses that can benefit from the use of Multimodal interactions. In todays networks, Multimodal interactions are particularly relevant to the mobile space, where constraints of the network and handset have a driving influence on the interactions available to everyday mobile users. This paper describes some of the concurrent technical issues involved in building Multimodal systems within a Telecom and provides indicators to the future Multimodal concepts.
Word Sense Embedded in Geometric Spaces - From Induction to Applications using Machine Learning

Words are not detached individuals but part of a beautiful interconnected web of related concepts, and to capture the full complexity of this web they need to be represented in a way that encapsulates all the semantic and syntactic facets of the language. Further, to enable computational processing they need to be expressed in a consistent manner so that similar properties are encoded in a similar way. In this thesis dense real valued vector representations, i.e. word embeddings, are extended and studied for their applicability to natural language processing (NLP). Word embeddings of two distinct flavors are presented as part of this thesis, sense aware word representations where different word senses are represented as distinct objects, and grounded word representations that are learned using multi-agent deep reinforcement learning to explicitly express properties of the physical world while the agents learn to play Guess Who? The empirical usefulness of word embeddings are evaluated by employing them in a series of NLP related applications, i.e. word sense induction, word sense disambiguation, and automatic document summarisation. The results show great potential for word embeddings by outperforming previous state-of-the-art methods in two out of three applications, and achieving a statistically equivalent result in the third application but using a much simpler model than previous work.
Validity and reliability of the guidelines of the Surveillance of Cerebral Palsy in Europe for the classification of cerebral palsy

The validity and reliability of the guidelines of the Surveillance of Cerebral Palsy in Europe (SCPE) for the classification of cerebral palsy (CP) were tested by administering 10 written case vignettes via an interactive web‐based link to 30 SCPE partners. There was a moderately good level of agreement (κ=0.59) about inclusion as a CP case on the SCPE database. Classification by CP subtype differed in two main areas: assigning spastic versus dyskinetic and judgement of distribution of spastic involvement. Agreement on Gross Motor Function Classification System (GMFCS) level was less good than reported in previous studies. Twenty respondents repeated the test 5 months later and there was good repeatability for case inclusion (κ= 0.72) but considerable variation in assignment of CP subtype and GMFCS level. There is a need for further collaborative work and training to improve harmonization of the classification of CP, including examination, application of SCPE guidelines, and register coding.
Predicting Stock Liquidity by Using Ensemble Data Mining Methods

In finance literature, stock liquidity showing how stocks can be cashed out in the market has received rich attentions from both academicians and practitioners. The reasons are plenty. First, it is known that stock liquidity affects significantly asset pricing. Second, macroeconomic announcements influence liquidity in the stock market. Therefore, stock liquidity itself affects investors" decision and managers" decision as well. Though there exist a great deal of literature about stock liquidity in finance literature, it is quite clear that there are no studies attempting to investigate the stock liquidity issue as one of decision making problems. In finance literature, most of stock liquidity studies had dealt with limited views such as how much it influences stock price, which variables are associated with describing the stock liquidity significantly, etc. However, this paper posits that stock liquidity issue may become a serious decision-making problem, and then be handled by using data mining techniques to estimate its future extent with statistical validity. In this sense, we collected financial data set from a number of manufacturing companies listed in KRX (Korea Exchange) during the period of 2010 to 2013. The reason why we selected dataset from 2010 was to avoid the after-shocks of financial crisis that occurred in 2008. We used Fn-GuidPro system to gather total 5,700 financial data set. Stock liquidity measure was computed by the procedures proposed by Amihud (2002) which is known to show best metrics for showing relationship with daily return. We applied five data mining techniques (or classifiers) such as Bayesian network, support vector machine (SVM), decision tree, neural network, and ensemble method. Bayesian networks include GBN (General Bayesian Network), NBN (Naive BN), TAN (Tree Augmented NBN). Decision tree uses CART and C4.5. Regression result was used as a benchmarking performance. Ensemble method uses two typesintegration of two classifiers, and three classifiers. Ensemble method is based on voting for the sake of integrating classifiers. Among the single classifiers, CART showed best performance with 48.2%, compared with 37.18% by regression. Among the ensemble methods, the result from integrating TAN, CART, and SVM was best with 49.25%. Through the additional analysis in individual industries, those relatively stabilized industries like electronic appliances, wholesale & retailing, woods, leather-bags-shoes showed better performance over 50%.
Human immunodeficiency virus (HIV)-specific immune responses are generated with the simultaneous vaccination of a gp120-depleted, whole-killed HIV-1 immunogen with cytosine-phosphorothioate-guanine dinucleotide immunostimulatory sequences of DNA.

OBJECTIVES We compared the effect of priming with a synthetic oligodeoxynucleotide (ODN) immunostimulatory DNA sequence followed by vaccination with human immunodeficiency virus type 1 (HIV-1) in incomplete Freund's adjuvant (IFA) or HIV-1 antigen alone to the simultaneous administration of immunostimulatory sequences (ISS) with HIV-1 in IFA. METHODS We examined immune function involving interferon-gamma (IFN-gamma) production, RANTES (regulated upon activation, normal T cell expressed and secreted) production, and lymphocyte proliferation, all of which appear to be augmented in HIV-1-exposed, but uninfected, individuals. RESULTS We demonstrate that similar levels of antigen-specific IFN-gamma were produced from lymph node cells of the animals immunized with HIV-1 antigen in IFA containing the CpG ODN 1826 (ISS; mean +/- SE = 450.8 +/- 224.3 pg/mL) and the group of animals primed with the ODN before injection with the HIV-1 in IFA (mean +/- SE = 377.7 +/- 294.8 pg/mL) or HIV-1 antigen alone (IFN-gamma = 0 pg/mL). However, the group that received the HIV-1 in IFA plus ISS mounted a stronger lymphocyte proliferation (mean net +/- SE = 29,180 +/- 1,932 cpm) compared to the group primed with the ODN before injection with HIV-1 in IFA (mean net +/- SE = 8,575 +/- 2,978 cpm). Furthermore, the group that received the HIV-1 in IFA plus ISS also mounted stronger beta-chemokine production measured as RANTES (mean +/- SE = 1,217 +/- 267.4 pg/mL) compared to the group that received the ODN before injection with HIV-1 in IFA (mean +/- SE = 129.1 +/- 48.5 pg/mL). Antibody responses from the group that received the HIV-1 in IFA plus ISS also showed a higher p24-specific response that was predominantly of the immunoglobulin G IgG2b isotype. CONCLUSION These results suggest that the simultaneous administration of the ISS in the HIV-1 in IFA emulsion may be a condidate for testing in non-human primates and in human studies as a therapeutic and preventative vaccine.
Enterprise Development in SMEs and Entrepreneurial Firms: Dynamic Processes

In order to increase the economic opportunities available, enterprise development plays a crucial role in the progression of socio-economic development for small and medium enterprises.Enterprise Development in SMEs and Entrepreneurial Firms: Dynamic Processes explores the process of enterprise development and its reconstruction of entrepreneurial identities, critical competencies as well as market turnaround for SMEs. This book aims to be a critical resource in the understanding of enterprise strategies adopted and lessons learned for management development. It is a successful resource for students, researchers and professionals interested in the growth SMEs.
Relationship between Characteristics of Virtual Brand Community and Brand Attachment for Nokia BBS Users

Brand attachment is a relationship between the enterprise and consumers which is of a higher level and stronger strength than repeated purchase behavior. Virtual brand community provides a medium of exchange for brand information, experience and feeling for customers, can supply extra brand involvement and brand value, and is an important carrier of the establishment of brand attachment relationship. This paper explores and builds the model of relationship between characteristics of virtual brand community and brand attachment. The characteristics of virtual brand community include participation of community members, quality of information system and community service management etc. And through the survey of random samples of 145 Nokia BBS members, we have found that “community service management, community participation degree and frequency” has significantly positive influence on brand attachment. Therefore, to improve community management and to attract wide participation of users is an effective way of strengthening the brand attachment of consumers to Nokia.
Risk factors Related to Rhabdomyolysis in Thai Statin Users: A Case-control Study

Previous studies on statin have revealed that increasing age, renal insufficiency, and concomitant medications were associated with rhabdomyolysis. However, there is a lack of analysis on the magnitude of such association in the Asia-Pacific region. The objectives of this study were to identify risk factors of statin-associated rhabdomyolysis in Thai patients and to evaluate the magnitude of association between the risk factors and rhabdomyolysis. The casecontrol study was carried out at five tertiary-care hospitals in Thailand and patients’ data of 2005-2008 were collected. Data of cases with rhabdomyolysis were extracted from patient’s profiles. For each case, the researchers randomly selected ten controls for making a comparison. Data extracted included demographics, type of statins, dosage, duration, and concomitant medications. No matching of controls to cases was performed in this study and the data collectors were not blinded. Of the 220 patients, the three most commonly used were simvastatin (80.0%), atorvastatin (15.0%), and rosuvastatin (5.0%). A univariable analysis indicated that the most powerful risk factor for rhabdomyolysis was renal disease, odds ratio (OR, 24.00; 95% CI, 6.6885.49). The number of concomitant medications was also associated with significant increased risk of rhabdomyolysis, OR 3.85 (95% CI, 1.40-10.61) and 13.23 (95% CI, 1.54-113.62) for one and two concomitant medications, respectively. In multivariable analysis, the only significant association found was between renal disease and rhabdomyolysis with a Coefficient 3.46 (95% CI, 2.21-4.71). This study reiterates that renal disease plays a key role in precipitating statin-associated rhabdomyolysis. Impaired renal function could lower elimination of statins and concomitant drugs, resulting in drug interactions and rhabdomyolysis. Keyword: statin, rhabdomyolysis, risk factor, drug interaction, renal disease.
Centralized biorepositories for genetic and genomic research.

MEDICAL PRACTICE IS BEING TRANSFORMED BY MOlecular analyses of biological samples that provide prognostic and diagnostic information for clinical care. The analytical methods and technologies that have accompanied the sequencing of the human genome have been the subject of research on their accuracy, reliability, and precision, but far less attention has been paid to the storage methods and archiving of the specimens required for analysis. Indeed, well-annotated biospecimen collections have enabled the recent identification of genes and genetic loci thought to contribute to susceptibility for several complex diseases. Some of these genomewide association studies were based on governmentsponsored, centralized collections. However, biorepositories with standardized procedures, informatics, and embedded regulatory compliance remain rare and the state of storage of human biospecimens is often decentralized and poorly organized at many of the US medical centers. Human tissue has been collected and stored at medical and research institutions in the United States for more than 100 years. By 2000, more than 300 million human biospecimens had been stored in freezers across the United States with an estimated accrual rate of an additional 20 million specimens annually. In 2004, the National Cancer Institute estimated that it spends more than $50 million yearly on banking samples from cancer patients as part of 125 funded research programs and projects. Academic medical centers historically have discharged the responsibility of biospecimen sample and data storage to individual investigators who have developed “home remedies” to meet specific research objectives, often with limited resources and inconsistent funding. The result is a decentralized system of ad hoc solutions that, despite facilitating great advances, often lack standards, are inefficient, and create a liability for the institutions and their researchers. Most institutions today cannot readily access a list of samples stored on institutional premises, let alone ascertain the conditions under which they are stored or who donated them. With a greater reliance on sample-derived data for genetic and genomic research and clinical care, improved standards and informatics for sample procurement, storage, and analysis are required to maximize the value of tissue collection for research participants, investigators, medical centers, and funding agencies.
Optima design of contact opening for relieving current crowding effect in flip-chip solder joints

The simulation results show that larger contact opening may not benefit on relieving current crowding effect in the flip-chip solder joints. For the solder joints with a 10-µm thick Cu UBM, the diameter of the contact opening for the lowest current crowding effect is 60 µm. It means that using larger or smaller diameter will increase the current density in the solder bumps. In addition, the optima diameter of the contact opening with a thin-film UBM is larger than that with a thick UBM. In this letter, the optimal design rule of contact opening for relieving current crowding effect in solder joints will be provided.
Structuring objectives of media companies: a case study based on value-focused thinking and the balanced scorecard

ABSTRACT Objectives are fundamental to strategic management. However, while research exists on objectives of media companies, we know little about the relationships between them. In order to advance research in this field, we used value-focused thinking to investigate the objectives of a media company and the balanced scorecard as a framework to demonstrate their relationships. In interviews with 23 managers and employees of a German medium-sized local newspaper company, we found 698 distinct objectives and 1009 relationships. By concentrating on the most important objectives, we derived a balanced scorecard with 33 objectives and 65 relationships organised in seven perspectives. The results were then validated in a second case study on a Czech national media group.
Regional divergence and mosaic spatial distribution of two closely related damselfly species (Enallagma hageni and Enallagma ebrium)

North American Enallagma damselflies radiated during the Pleistocene, and species differ mainly by reproductive structures. Although morphologically very different, Enallagma hageni and Enallagma ebrium are genetically very similar. Partitioning of genetic variation (AFLP), isolation by distance and clustering analyses indicate that these morphospecies are locally differentiated genetically. Spatial analyses show that they are rarely sympatric at local sites, and their distributions form a mosaic of patches where one is clearly dominant over hundreds of square kilometers. However, these morphospecies are also not genetically more similar when they are sympatric, indicating that hybridization is probably not occurring. Given that these morphospecies are ecologically equivalent, strong assortative mating, reproductive interference and fast post‐glacial recolonization may explain the origin and maintenance of these distributional patches across eastern North America. By limiting opportunities for gene flow, reproductive interference may play an unsuspected role in accelerating genetic differentiation in the early phases of nonecological speciation.
The genetic variation of the tenomodulin gene (TNMD) is associated with serum levels of systemic immune mediators—the Finnish Diabetes Prevention Study

Purpose: We have reported that the genetic variation of the tenomodulin gene (TNMD) is associated with the risk of type 2 diabetes (T2DM), central obesity, and impaired glucose metabolism and the TNMD mRNA levels correlate with serum and mRNA levels of inflammatory markers. Our objective was to investigate the genetic associations of the single nucleotide polymorphisms of the TNMD gene with the serum levels of systemic immune mediators.Methods: Seven single nucleotide polymorphisms were genotyped from 507 participants of the Finnish Diabetes Prevention Study. All subjects had body mass index >25 and impaired glucose tolerance.Results: The sequence variation of tenomodulin was consistently associated with the serum concentrations of acute phase reactants, macrophage migration inhibitory factor, and CCR5 receptor ligands. The genotype effects were modified by status of glucose metabolism and central obesity. Markers associated with increased risk of T2DM in our previous study were associated with serum concentrations of acute phase proteins in men so that the subjects possessing the genotypes associated with increased risk of T2DM had higher serum concentrations of acute phase reactants.Conclusions: These results indicate that the genetic variation of TNMD is associated with low-grade inflammation. The putative link between TNMD and T2DM could be mediated through the effects on systemic immune mediators.
The Experience of Spouses as Informal Caregivers for Recipients of Hematopoietic Stem Cell Transplants

Spouses often are the primary caregiver for the hematopoietic stem cell transplant (HSCT) recipients and participate in the transplant recipients' care throughout the HSCT trajectory. The purpose of this qualitative study was to explore and describe the experiences of spouses of HSCT recipients during the acute phase of the transplant trajectory. The participants were spousal caregivers (8 wives and 3 husbands) of transplant recipients. Each participant was interviewed 1 to 6 times. Data were analyzed using Spradley's domain analysis. As couples entered the transplant experience, spouses described a sense of dislocation from normal life. They were now riding a rollercoaster in the dark as they lived the uncertainty of this risky therapy. Spouses structured the uncertainty with rituals, formed a positive perspective, and envisioned the future. They described a caregiving role but also needed to balance "me and my world" with "us and our world. "