Miracle-dz/UniFAR-FTUs huggingface dataset:
The Course of Adjustment Disorder Following Involuntary Job Loss and Its Predictors of Latent Change

Adjustment disorders (AjDs) usually resolve after the precipitating life event and its consequences are terminated. However, they bear the risk for the development of severe mental illness. The present study investigates the natural course of AjD as defined for International Classification of Diseases, 11th version (ICD-11). A total of 303 individuals who involuntarily lost their jobs were assessed initially after the job loss and 6 months later. Latent class latent change analysis and multinomial logistic regression were performed. Two groups showed low (n = 149, 49.2%) and medium (n = 108, 35.6%) symptom severity at initial assessment that declined over time. The third group (n = 46, 15.2%) showed a high initial response and a small effect of worsening of symptoms. Female gender, higher age, first dismissal, impaired social functioning, dysfunctional disclosure, less social support, and less social acknowledgment were associated with belonging to the latter group. It might be beneficial to target individuals at high risk with interventions that aim at the improvement of skills relevant for stress management.
On the Performance of Digital Back Propagation in Spatial Multiplexing Systems

Nonlinear performance in spatial multiplexing systems is strongly determined by the interplay between differential mode delay, linear mode coupling, and Kerr nonlinearity. In this article we review and extend the analysis of different solution methods for the linear coupling operator in the coupled nonlinear Schrödinger equation for spatial multiplexed propagation. Numerical solution methods are compared for different operational regimes as determined by differential mode delay and linear mode coupling. Finally, we review and extend the study of digital methods to mitigate the Kerr nonlinearity for arbitrary levels of random linear mode coupling. For the first time, it is shown that in spatial multiplexing systems transmission performance can be improved by reducing the number of back propagated channels for non-negligible levels of differential mode delay.
Dietary Amino Acids Impact LRRK2-Induced Neurodegeneration in Parkinson's Disease Models

The G2019S mutation in leucine-rich repeat kinase 2 (LRRK2) is a common cause of Parkinson's disease (PD) and results in age-related dopamine neuron loss and locomotor dysfunction in Drosophila melanogaster through an aberrant increase in bulk neuronal protein synthesis. Under nonpathologic conditions, protein synthesis is tightly controlled by metabolic regulation. Whether nutritional and metabolic influences on protein synthesis can modulate the pathogenic effect of LRRK2 on protein synthesis and thereby impact neuronal loss is a key unresolved question. Here, we show that LRRK2 G2019S-induced neurodegeneration is critically dependent on dietary amino acid content in Drosophila studies with both sexes. Low dietary amino acid concentration prevents aberrant protein synthesis and blocks LRRK2 G2019S-mediated neurodegeneration in Drosophila and rat primary neurons. Unexpectedly, a moderately high-amino acid diet also blocks dopamine neuron loss and motor deficits in Drosophila through a separate mechanism involving stress-responsive activation of 5′-AMP-activated protein kinase (AMPK) and neuroprotective induction of autophagy, implicating the importance of protein homeostasis to neuronal viability. At the highest amino acid diet of the range tested, PD-related neurodegeneration occurs in an age-related manner, but is also observed in control strains, suggesting that it is independent of mutant LRRK2 expression. We propose that dietary influences on protein synthesis and autophagy are critical determinants of LRRK2 neurodegeneration, opening up possibilities for future therapeutic intervention. SIGNIFICANCE STATEMENT Parkinson's disease (PD) prevalence is projected to rise as populations continue to age, yet there are no current therapeutic approaches that delay or stop disease progression. A broad role for leucine-rich repeat kinase 2 (LRRK2) mutations in familial and idiopathic PD has emerged. Here, we show that dietary amino acids are important determinants of neurodegeneration in a Drosophila model of LRRK2 PD. Restricting all amino acids effectively suppresses dopaminergic neuron loss and locomotor deficits and is associated with reduced protein synthesis, while moderately high amino acids similarly attenuate these PD-related phenotypes through a stress-responsive induction of 5′-AMP-activated protein kinase and autophagy. These studies suggest that diet plays an important role in the development of PD-related phenotypes linked to LRRK2.
Improved collusion-resistant unidirectional proxy re-encryption scheme from lattice

Proxy re-encryption (PRE) is a promising cryptographic structure for pervasive data sharing in cloud-based social networks, which enables a semi-trusted proxy to convert a ciphertext for Alice into a ciphertext for Bob without seeing the corresponding plaintext. Since the proxy is semi-trust, a PRE scheme which can resist the collusion attack will be of great practical value. Jiang et al. in 2015 and Kim and Jeong in 2016 have proposed collusion-resistant PRE (CR-PRE) schemes from the lattice by a similar technique, respectively. However, through the analysis of their schemes, the authors find that both of them have defects in the construction of the re-encryption key, which will lead to the re-encryption ciphertext cannot be decrypted or decrypted error with high probability. In this study, the authors first point out the defects in the work of Jiang et al.'s work and Kim and Jeong's work and propose an improved collusion-resistant unidirectional PRE scheme from lattice, based on learning with errors problems. In addition to solving the defects, CR-PRE still has many useful properties similar to the previous schemes, such as unidirectional, collusion resistant, chosen-plaintext attack secure and so on.
Investigating the Relationship Between Mother-Child Bonding and Maternal Mental Health

Background: Mother-child bonding is rooted in the affective relationship between mother and child that is shaped during pregnancy and leads to the mental growth of infants. Objectives: This study was conducted to determine the relationship between mother-child bonding and maternal mental health in Ilam. Methods: In this descriptive-analytical study, 300 mothers in Ilam were selected using a two-stage cluster sampling method. The demographic characteristics questionnaire, the mother-infant bonding scale, Spielberger anxiety inventory, and edinburgh postnatal depression scale constituted the data collection instruments in this study, which were completed in the eighth to tenth postnatal week. Data were analyzed in SPSS via descriptive statistics (means and standard deviations) and inferential tests (t tests and ANOVA). Results: The results of this study revealed that the mean and standard deviation of the obtained mother-child bonding scores were 38. 48Â±12.86. Weakened mother-child bonding and risk of child abuse comprised the highest and lowest frequencies, respectively. Mother-child bonding had a statistically significant association with mothers' state anxiety, trait anxiety, and depression, and these variables affected mother-child bonding (P < 0.05). Conclusions: Considering the relationship between mother-child bonding and maternal mental health, proper screening is required to pursue secondary prevention in pregnant mothers. In addition, it is essential to perform necessary interventions to improve maternal mental health to facilitate better mother-child bonding. Â© 2018, Journal of Comprehensive Pediatrics.
Estudio longitudinal del IMC y de la Obesidad como factores de riesgo de rechazo del injerto renal

Objective. To evaluate the rejection, the chronic allograft nephropathy (CAN) and the delay in the function of the same (DGF) due to obesity and high BMI.Material and method. In this work, 500 patients of both sexes kidney transplant followed for 5 years were evaluated, post-transplant measurements of biochemical parameters and anthropometric measurements were made. It was also recognized data of chronic nephropathy and delayed graft function.Results: Five years after the transplant, there was an increase in BMI and an increase in the components of the metabolic profile: triglycerides, total cholesterol and hyperglycemia, as well as blood pressure. As a consequence we have also observed an increase in the incidence of chronic kidney disease and delayed graft function.Conclusion. Obesity significantly increases the incidence of post-transplant complications, which can finally be done through injection. An adequate control of BMI in kidney transplant recipients would directly influence long-term renal graft survival, which reduced the delay in allograft function, the appearance of CAN and prolonged renal allograft survival.
Drivers of cyberbullying intention: a study on Malaysian undergraduates’ perspectives

With the availability of the Internet and social media, cyberbullying cases in Malaysia have increased rapidly in recent years and they subsequently become the serious issues that inhibit the healthy development of Malaysian youth, particularly local undergraduates. Actually, cyberbullying is an act which is committed deliberately at multiple times to harm other individuals through and ICT environment. Thus, cyberbullies’ behaviour arises as a result of one’s intention which is caused by certain determinants. Apparently, the determinants that significantly influence an individual’s behavioural intention towards cyberbullying in this study are referred to the theory of planned behaviour (TPB) constructs and empathy. Hence, this research is aimed to determine whether the TPB and personality trait (i.e. empathy) can be used to explain the behavioural intention towards cyberbullying among Malaysian undergraduates. The self-administered questionnaires are delivered to 258 undergraduates who study in top 5 Malaysian universities. The research results have shown that attitude, subjective norms and perceived behavioural control have a positive relationship with behavioural intention towards cyberbullying. However, empathy is the only one independent variable that is found to have no significant association with dependent variable. Based on the research findings, attitude can be considered as the most significant predictor of behavioural intention towards cyberbullying when comparing to other independent variables which have been investigated in this study.
An charging Interface for Lithium ion Batteries Compatible with Current in-use UPS System

This work put forward the use of Lithium ion batteries as an energy storage medium with the existing uninterrupted power supplies, design for lead acid batteries by introducing an interface which takes care of different necessary parameters of Lithium Ion batteries is proposed. Li-ion battery has different voltage level per cell and demands more sophisticated control and safety measures as compare to Lead Acid battery. The interface will take its input from the UPS and will accordingly adjust its output for the Li-ion battery. The interface consists of a converter and a battery management system (BMS) for safe charging and discharging of Li-ion battery. A Li-ion battery pack topology is also proposed in the work, which ensures maximum energy extraction from the battery pack being used in UPS without compromising the life of battery pack and other constraints. Keywords— Li-ion, BMS, Uninterrupted power supply, lead
Influence of Secondary School Inspection on Lesson Planning in Western Uganda

The research is financed by the Danish Fellowship Centre (DFC) through the Building Stronger Universities Project of Gulu University, Uganda. Abstract School inspection is one of the leading factors in attaining better pedagogy including lesson planning. To that end, any attempt to improve the quality of lesson planning should be given the attention it deserves. This paper, therefore, examines how and to what extent inspection influences teachers’ lesson planning in secondary schools in Western Uganda. A concurrent triangulation mixed methods research design involving questionnaire survey and interview, with a total of 399 participants in the categories of school inspectors, teachers, head teachers, and deputy headteachers from 36 secondary school in Western Uganda, was adopted. Quantitative data were analysed using frequencies, ratios and Linear Regression Analysis while qualitative data were analysed using Qualitative Content Analysis. The study revealed that inspection did not significantly influence lesson planning in secondary schools. The study concluded that inspection has not contributed to improving lesson planning in secondary schools in Uganda. The research advances theory on inspection by demonstrating that merely visiting schools to conduct inspections does not necessarily lead to improvement in lesson planning. Improvement rather hinges on the ways that inspectors communicate, with teachers, prior, during and after the inspection. Understanding teachers’ beliefs, practices, and perceptions is important for improving educational processes. Keywords : Inspection, lesson planning, secondary schools, Uganda DOI : 10.7176/JEP/11-3-01 Publication date: January 31 st 2020
Management of Premature Ejaculation (Shukragata vata) with Erandamoola basti and Vanari kalpa: A Clinical Study

Introduction: Premature ejaculation (PE) is one of the most common sexual dysfunctions in men. Premature ejaculation is characterized with a short ejaculatory latency time, lack of ejaculatory control, decreased satisfaction with sexual intercourse causing interpersonal distress, negative impact on man’s selfesteem, reduced sexual function, and reduced quality of life. In Ayurveda, the problem is discussed under Shukragata vata. Functional approximation Shukra and Vata are quite evident in Ayurvedic principles. Erandamoola is described as the best Vrishya and Vatahara in Charaka Samhita, and Vanari gutika is mentioned for treatment of PE in Bhavprakash Samhita. Objective: To evaluate the efficacy of Erandamoola basti and Vanari kalpa (granules) in the management of PE. Materials and methods: Forty-five patients with PE were treated with Vanari kalpa granules for 2 months with milk (group II), Erandamoola basti for 16 days followed by Vanari kalpa granules for 2 months with milk (group III), and placebo control with wheat granules for 2 months with milk (group I). Psychological counseling was given to the patients in all the three groups. Results: Patients treated with Erandamoola basti and Vanari kalpa showed significant results against placebo in all the parameters, namely intravaginal ejaculation latency time (IELT), voluntary control over ejaculation, patient’s and partner’s satisfaction, and performance anxiety. Conclusion: The overall effect of therapy was higher in group III (Erandamoola basti followed by Vanari kalpa granules) with a better percentage of complete remission and marked improvement followed by groups II and I.
Tobacco Dependence Treatment: Pharmacist’s Role

Author(s): Gogineni, HP; Huang, B; Lin, J; Yang, F; Gogineni, RV; Lutfy, K | Abstract: Smoking prevalence and tobacco-related mortality have steadily declined in the recent decades. However, the use of e-cig and other nicotine containing products used for smoking cessation and other reasons is on the rise. Chronic use of tobacco products leads to serious health issues, yet a limited number of pharmacotherapies are available to treat smoking-related disorders. These pharmacotherapies in some cases are not effective or cause similar side effects as nicotine. Recently, with the inception of SB 493, pharmacists are authorized to be actively involved in smoking cessation. For example, California’s legislature granted pharmacists authority to furnish FDA-approved nicotine replacement therapies through SB 493. Thus, pharmacists must complete a training course approved by the board of pharmacy, as well as annual continuing education on tobacco cessation to be able to make the appropriate decision which product to choose for their patients. In this review, we attempted to review the available pharmacotherapies for smoking cessation and discuss the role that pharmacists play to help patients benefit from these products.
Suicide and the Media: From Werther to Papageno Effects – A Selective Literature Review

Et betydelig antall studier har vist at sensasjonspregete skildringer av selvmord i media kan utløse imitasjonsselvmord; dette er ofte omtalt som «Werther-effekten». For å forhindre skadelige medieeffekter, har nasjonale og internasjonale organisasjoner utviklet anbefalinger for omtale av selvmord i mediene for å endre praksis i hvordan selvmord beskrives og for å styrke fokuset på selvmordsforebyggende aspekter. I løpet av det siste tiåret har man fått mer kunnskaper som viser at visse typer medieomtale av selvmord kan ha forebyggende effekt. Særlig medie- saker som beskriver personlige erfaringer med selvmords- tanker og hvordan man kan overvinne og takle vanskelige livssituasjoner, har vist seg å redusere suicidalitet i enkelte grupper. Denne beskyttende effekten har blitt kalt Papageno-effekten. I denne artikkelen gir vi en selektiv oversikt over aktuell litteratur om Werther- og Papagenoeffektene for forskjellige typer medier, og legger særlig vekt på nye kunnskaper om Papageno-effekten generert fra randomisert kontrollerte studier. Vi viser hvordan disse effektene kan utnyttes i selvmordsforebyggende arbeid ved samarbeid med media, og peker på fortsatte mangler i kunnskapene som må fokuseres i fremtidig forskning.
Propagation of Some Medicinal and Aromatic Plants in Turkey by Biotechnological Methods

Bu calismada, Turkiye’de tibbi amacli olarak kullanilan Sideritis perfoliata L . , S. stricta Boiss. & Heldr. , S. erythrantha Boiss. & Heldr. , Leucojum aestivum L. , Borago officinalis L. , Cuminum cyminum L. , Lavandula angustifolia Mill. , Rosa damascena Mill. , R. canina L. , Thymus longicaulis subsp. longicaulis C.pres l. , Tussilago farfara L. , Digitalis lanata Ehrh . , D. lamarckii Ivan. , Crocus sativus L. , Capsicum annuum L . , Origanum syriacum subsp. bevanii (Holmes) Greuter & Burdet, Ecballium elaterium (L.) A. Rich . , Sinapis arvensis L. , Papaver somniferum L. , P. bracteatum Lindl. , Capparis spinosa L. , Coriandrum sativum L . , Petroselinum crispum (Mill.) A. W. Hill. , Silybum marianum (L.) Gaertn . , Ziziphus jujuba Mill. , Peganum harmala L. , Carthamus tinctorius L. , Rumex acetosella L. , Dianthus caryophyllus L. , Ocimum basilicum L. , Mentha spicata subsp. spicata L. taksonlarinin biyoteknolojik yontemlerle uretimi, cogaltimi ve islah calismalarina yonelik 1984-2019 yillari arasinda yapilan arastirmalar derlenmistir. Tibbi ve aromatik bitkilere olan ihtiyaci karsilamaya yonelik uretimin yapilabilmesi ve istenen verimin alinabilmesi icin, bitkilerde in vitro sartlarda organogenesis, somatik embriyogenesis gibi biyoteknolojik yontemler kullanilabilmektedir. Ayni zamanda biyoteknolojik yontemlerle cesitli islah calismalari da gerceklestirilebilmektedir. Tibbi ve aromatik bitkilerde klasik cogaltim yontemlerinin disinda in vitro cogaltim teknikleri ile yogun ve klonal bir cogaltimin saglanmasi, buyuk bir potansiyel olarak ortaya cikmaktadir.
The influence of post-diuretic late phase imaging in visual and quantitative evaluation of urothelial tumors by F-18 fluorodeoxyglucose positron emission tomography/computed tomography.

OBJECTIVE Although F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is a valuable imaging method in most of the malignant tumors, it is considered to have limited diagnostic ability in urothelial tumors due to high physiologic urine activity. The aim of the present study was to evaluate the effect of post-diuretic late phase imaging to the visual and quantitative evaluation of urothelial tumors in the staging and restaging of the patients. MATERIAL AND METHODS Two patients with ureter and 40 patients with bladder tumors (6 females and 36 males, mean age: 67.12±8.79 years) who were referred for staging or restaging or treatment response evaluation to the F-18 FDG PET/CT were included in the study. Late phase (at the second hour after FDG injection) images including the renal pelvis and bladder region after the administration of approximately 40 mg furosemide were obtained after standard oncologic F-18 FDG PET/CT imaging. The images were evaluated by visual and quantitative interpretation, and index values were calculated. Paired samples T test was used to decide the significance of the difference between the early and late phase images. A p value <0.05 was considered significant. RESULTS The activity accumulation in the primary or recurrent lesions in the bladder or ureter in the early and late phase images was statistically significantly different. Additionally, in 15/41 (37%) patients, the primary tumor in the bladder was only determined in late phase images, and additional lymph node metastases adjacent to the bladder or ureter were only observed in diuretic late phase images in some of the patients. The sensitivity, specificity, and diagnostic accuracy of the PET/CT with this methodology for N staging and M staging were 67%, 78%, and 82% versus 80%, 91%, and 82%, respectively. CONCLUSION Late phase imaging after diuretic administration should be performed in case of non-visualization of primary tumor in the bladder region. The late phase post-diuretic imaging revealed significant improvement in the visual and quantitative diagnostic performance of the FDG PET/CT and has high diagnostic accuracy for the staging of urothelial tumors.
Uji Efektivitas Daun Belimbing Wuluh (Averrhoa bilimbi L.) sebagai Pengobatan Diabetes Melitus

Diabetes melitus merupakan suatu penyakit metabolik yang ditandai dengan terjadinya peningkatan kadar glukosa dalam darah akibat kurangnya sekresi insulin, kerja insulin, ataupun keduanya. Kadar glikemi yang berlebihan dapat menyebabkan terbentuknya radikal bebas untuk menjadi suatu oksigen reaktif. Daun belimbing wuluh (Averrhoa bilimbi L.) adalah tumbuhan yang telah dipercayai dapat digunakan sebagai pengobatan herbal dalam mengatasi diabetes mellitus. Kandungan di dalam daun belimbing wuluh yang paling berperan penting sebagai antioksidan dan antidiabetes adalah Flavonoid. Flavonoid merupakan senyawa fenol yang memiliki beberapa aktivitas farmakologikal. Metode yang digunakan adalah metode maserasi. Dalam metode ini telah cukup dibuktikan melalui suatu penelitian bahwa daun belimbing wuluh bersifat poten terhadap penyakit diabetes. Selain itu daun belimbing wuluh juga memiliki aktivitas antibekteri terhadap Escerichia coli dan Staphylococcus aureus. Tingkat prevalensi penderita diabetes di Indonesia semakin meningkat setiap tahunnya. Kata kunci: Averrhoa bilimbi L. ,diabetes mellitus, ekstraksi maserasi, flavonoid, herbal