Miracle-dz/UniFAR-FTUs huggingface dataset:
The role of encoding in reality monitoring: A running memory test with Alzheimer's type dementia

Reality monitoring refers to the discrimination between memories of internal and external events (e.g., Johnson & Raye, 1981). A total of 28 healthy older adults and 28 older adults with Alzheimer's type dementia (DAT) were asked to perform or to imagine performing simple action statements in a running memory test. This task required participants to tell whether the action statement had been carried out or imagined, or whether it was new at unpredictable intervals. The results indicated that older adults with DAT had greater difficulty in reality monitoring than did the healthy control group. The finding is discussed in terms of the role of working memory functions in reality monitoring.
Sistema FOQuE para Expansão Semântica de Consultas Baseada em Ontologias Difusas

As availability of data has been growing, it is becoming even more necessary to develop effective techniques to retrieve the desired information, in order to reduce irrelevant answers and ensure that relevant results are not igno- red. In this sense, this paper presents the FOQuE system, developed to perform semantic query expansion based on fuzzy ontologies, making possible to retri- eve approximate results that satisfy user requirements according to expansion parameters defined by him. The additional answers retrieved by the FOQuE system are classified regarding both the semantic expansion performed and the relevance to the query, therefore improving the way results are presented to the user. Resumo. Diante da crescente facilidade de acesso aos dados, cada vez mais sao necessarias tecnicas eficazes para recuperar a informacao desejada, vi- sando reduzir respostas irrelevantes e assegurar que resultados relevantes nao sejam desprezados. Neste sentido, este artigo apresenta o sistema FOQuE para expansao semântica de consultas baseada em ontologias difusas, que permite recuperar resultados aproximados que satisfacam aos requisitos do usuario, de acordo com parâmetros de expansao definidos por ele. As respostas adicionais recuperadas pelo sistema FOQuE sao classificadas conforme o tipo de expan- sao realizada e a relevância para a consulta, melhorando, assim, a forma como os resultados sao apresentados ao usuario.
A vertebrate fatty acid desaturase with Δ5 and Δ6 activities

Δ5 and Δ6 fatty acid desaturases are critical enzymes in the pathways for the biosynthesis of the polyunsaturated fatty acids arachidonic, eicosapentaenoic, and docosahexaenoic acids. They are encoded by distinct genes in mammals and Caenorhabditis elegans. This paper describes a cDNA isolated from zebrafish (Danio rerio) with high similarity to mammalian Δ6 desaturase genes. The 1,590-bp sequence specifies a protein that, in common with other fatty acid desaturases, contains an N-terminal cytochrome b5 domain and three histidine boxes, believed to be involved in catalysis. When the zebrafish cDNA was expressed in Saccharomyces cerevisiae it conferred the ability to convert linoleic acid (18:2n-6) and α-linolenic acid (18:3n-3) to their corresponding Δ6 desaturated products, 18:3n-6 and 18:4n-3. However, in addition it conferred on the yeast the ability to convert di-homo-γ-linoleic acid (20:3n-6) and eicosatetraenoic acid (20:4n-3) to arachidonic acid (20:4n-6) and eicosapentaenoic acid (20:5n-3), respectively, indicating that the zebrafish gene encodes an enzyme having both Δ5 and Δ6 desaturase activity. The zebrafish Δ5/Δ6 desaturase may represent a component of a prototypic vertebrate polyunsaturated fatty acids biosynthesis pathway.
Exploration of Triticeae seed storage proteins for improvement of wheat end-product quality

The seed storage proteins (SSPs) of cultivated wheat (Triticum aestivum and T. durum), namely, glutenin and gliadin, impart viscoelastic properties to bread dough, making wheat well suited for bread-making. Extensive studies on wheat SSPs have been carried out and revealed genetic diversity among wheat cultivars. Here, we review the studies of SSPs from more exotic species in the Triticeae tribe, primarily based on our own recent studies. SSPs of barley (Hordeum vulgare), homologous to those in wheat, exhibit quite different properties to wheat SSPs and do not produce viscoelastic dough. However, SSPs of a wild barley species (H. chilense) possess similar characteristics to the proteins of wheat. SSPs of rye (Secale cereale) substituted for wheat SSPs result in inferior quality. SSPs of Aegilops searsii and Ae. longissima have positive effects on quality, while Ae. umbellulata and Ae. geniculata (Ug genome) SSPs have a negative effect on bread-making quality. SSPs located on chromosome 1Mg of Ae. geniculata and a chromosome 1E of Thinopyrum elongatum have positive effects in addition lines but not in substitution lines for chromosome 1D of wheat. In contrast, SSPs of Th. intermedium have positive effects, even in cases of substitution for chromosome 1D of wheat, indicating promising potential for improvement of bread-making quality of wheat. Based on these results, we discuss the possibilities for utilizing the genetic variation of exotic Triticeae species for breeding improved quality traits in wheat.
The sunflower (Helianthus annuus L.) genome reflects a recent history of biased accumulation of transposable elements.

Aside from polyploidy, transposable elements are the major drivers of genome size increases in plants. Thus, understanding the diversity and evolutionary dynamics of transposable elements in sunflower (Helianthus annuus L.), especially given its large genome size (∼3.5 Gb) and the well-documented cases of amplification of certain transposons within the genus, is of considerable importance for understanding the evolutionary history of this emerging model species. By analyzing approximately 25% of the sunflower genome from random sequence reads and assembled bacterial artificial chromosome (BAC) clones, we show that it is composed of over 81% transposable elements, 77% of which are long terminal repeat (LTR) retrotransposons. Moreover, the LTR retrotransposon fraction in BAC clones harboring genes is disproportionately composed of chromodomain-containing Gypsy LTR retrotransposons ('chromoviruses'), and the majority of the intact chromoviruses contain tandem chromodomain duplications. We show that there is a bias in the efficacy of homologous recombination in removing LTR retrotransposon DNA, thereby providing insight into the mechanisms associated with transposable element (TE) composition in the sunflower genome. We also show that the vast majority of observed LTR retrotransposon insertions have likely occurred since the origin of this species, providing further evidence that biased LTR retrotransposon activity has played a major role in shaping the chromatin and DNA landscape of the sunflower genome. Although our findings on LTR retrotransposon age and structure could be influenced by the selection of the BAC clones analyzed, a global analysis of random sequence reads indicates that the evolutionary patterns described herein apply to the sunflower genome as a whole.
Dental Implant Treatment in Diabetic Patients

The purpose of the present study was twofold: (1) to investigate how many diabetic patients and types of cases that are treated with dental implants in our clinic; and (2) assess the outcome of such treatment. Medical records from 782 patients were examined in patients treated by the Brånemark method for partial or total edentulism with implant supported bridges. From these records, 25 patients (3.2%) with diabetes before implant treatment (136 implants) were identified and further studied with respect to age, gender, type of diabetes, treated jaw, degree of edentulism, bone graft, implant survival, periimplant inflammation, bleeding on probing, and radiographic bone loss. Furthermore, the patients’ opinion about the outcome of the treatment was registered. The implant success rate was 96.3% during the healing period and 94.1% 1 year after surgery. Of all 38 bridges, one was lost. Few complications occurred and all patients, except for one, were satisfied with the treatment. Today, diabetic patients are being treated successfully for all types of edentulism, including bone-grafting treatment. Diabetics that undergo dental implant treatment do not encounter a higher failure rate than the normal population, if the diabetics’ plasma glucose level is normal or close to normal as assessed by personal interviews.
Synchronization algorithm for multiuser digital IR-UWB system

This paper proposes a novel synchronization algorithm for multiuser digital impulse radio (IR) ultra-wideband (UWB) system. The proposed algorithm is based on pseudo-noise (PN) training sequence, and different users employ different PN sequences. To reduce the overhead of the preamble, monocycle pulse is used to modulate one bit information of training sequence. The proposed scheme includes acquisition and timing (fine synchronization) algorithms. Acquisition and coarse channel estimation are firstly gotten. After that, timing and channel estimation can be derived at the same time naturally through energy searching. In multipath channel, no interference among the pulses inner preamble is guaranteed and inter frame interference (IFI) inner one symbol during payload transmitting is allowed. At receiver, demodulation template is derived by combining the channel estimation according to time hopping (TH) code. Correlation detection can be carried out to demodulate the data. Simulation results validate the proposed scheme.
Incremental motion control of permanent magnetic synchronous motor

Stepping motor is the main actuator of incremental motion control system. The permanent magnetic synchronous motor (PMSM), as well as the stepping motor, can work in stepping mode if suitable driving method is applied. This paper study the open-loop stepping drive theory and method of PMSM. A new open-loop compensation method of PWM dead-time is introduced to improve the control precision of winding current and also improve the precision of step interval under stepping drive mode.
Hybrid tomography for conductivity imaging

Hybrid imaging techniques utilize couplings of physical modalities—they are called hybrid, because typically, the excitation and measurement quantities belong to different modalities. Recently there has been an enormous research interest in this area because these methods promise very high resolution. In this paper, we give a review on hybrid tomography methods for electrical conductivity imaging. The reviewed imaging methods utilize couplings between electric, magnetic and ultrasound modalities. By this it is possible to perform high-resolution electrical impedance imaging and to overcome the low-resolution problem of electric impedance tomography.
Inhibitor effects of diltiazem, nicardipine, nifedipine and verapamil on the norepinephrine-induced contractions of the canine saphenous vein in calcium-free medium.

Contractile responses to norepinephrine (noradrenaline, NE 10(-5) M) in the canine saphenous vein (SV) are significantly, although slightly, reduced (14%) when induced in a physiological medium depleted of calcium for 1 hour (+ EGTA). In contrast, they are inhibited by about 75% after 24 hr in calcium free physiological saline solution (P.S.S.). ED50 of norepinephrine in 1-hr calcium-free medium and in normal Ca++ P.S. S. are 6 x 10(-7)M and 4.2 x 10(-7)M, respectively. Two blockers of extracellular calcium entry have also been cited as inhibitors of intracellular calcium pool refilling. At concentrations of 10(-6)M, 10(-5)M and 10(-4)M, diltiazem and nicardipine inhibit the norepinephrine-induced contractions (NIC) in a concentration-dependent manner. At 10(-4)M, the two calcium blockers inhibit the NIC by 70% and by 72% respectively in Ca++ free (+ EGTA) P.S. S. Nifedipine and verapamil only begin to significantly inhibit NIC in Ca++ free (+ EGTA) P.S. S. at concentrations equal to or greater than 10(-5)M. At 10(-4)M concentration, control inhibition in Ca++ free P.S. S. was observed as 60% and 49%, respectively. Contrary to the other 3 calcium antagonists tested, diltiazem antagonises NIC significantly less in calcium-containing medium (45%) than in calcium-free medium (72%). Procaine at a concentration of 10(-3)M, described as sufficient to totally inhibit calcium release from its intracellular storage sites, only inhibits NIC by 52% in calcium free (+ EGTA) P.S. S. These results are consistent with the following conclusion: i) in the canine saphenous vein (SV), NIC is mainly mediated by calcium mobilization from its intracellular storage sites; ii) the calcium antagonists tested here and procaine are unable to totally inhibit, even at high concentrations, the contractions induced via intracellular calcium release; this characteristic is nonsignificant for nifedipine and verapamil at low concentrations (10(-6)M). iii) verapamil and nifedipine, like diltiazem and nicardipine at high concentrations, may not only possess the characteristics of extracellular calcium entry blockers, but also that of partial antagonist of NIC via non specific mechanisms; iv) diltiazem may relax the vascular smooth muscle of SV, not only by the above two properties, but also through another mechanism yet unknown; v) partial persistence of NIC on the SV under conditions of short or long extracellular calcium depletion may be due to a mechanism of intracellular Ca++ recycling, the smooth muscle cell partially retaining its intracellular Ca++.
Platform Structures, Homing Preferences, and Homophilous Propensities in Online Social Networks

Abstract This study investigates how the attributes of online social platforms (e.g., open vs. closed, symmetric vs. asymmetric social networks) and user preferences regarding platform diversity (e.g., single-homing vs. multi-homing) moderate the influence of homophily on user behaviors across varied social segments. On the basis of panel data, we delve into the interplay among homophily, structural diversities across various online social networking services (SNSs), and users’ homing preferences in such social platforms. The data feature of the SNS consumption behaviors of 10,172 individual users are obtained over a period of 134 days. An agent-based simulation model is developed to further validate and generalize the empirical findings. The simulation and empirical results consistently indicate that propensity toward homophily differs significantly across platform types and users’ channel adoption behaviors. Online homophily is more pronounced in closed, private social networks than in open, public social networks. Users of asymmetric and symmetric SNSs exhibit weak and strong homophily, respectively. Moreover, whereas users who adopt a single SNS channel tend toward homophily, those who subscribe to multiple SNSs confirm the idea that “opposites attract. ” These findings suggest that users of online SNS channels manifest complex human interactions typified by the combination of homophily, heterophily, and asymmetric social preference, although homophily is the most prominent disposition. Our findings suggest that homophily should be considered a dynamically changing human characteristic rather than a static attribute, and stakeholders should exploit the complex nature of users’ homophilous behaviors to address social problems in online SNSs and to enhance the effectiveness of social advertising.
The cutaneous manifestations of paraproteinaemia. I

Paraproteins that result from a monoclonal proliferation of immunoglobulin-secreting cells (B cells) are associated with a wide variety of skin disorders. In certain instances, the pathogenetic role of the paraprotein is well established. In other cases the associations remain unexplained. This review attempts to classify these disorders with particular regard to the mechanisms that are thought to underlie the clinical conditions (see Appendix). The terms 'M' component disease, paraproteinaemia and monoclonal gammopathy are used synonymously to indicate excess immunoglobulin production by a clone of B cells without specifying whether this activity is benign or malignant. The presence within the skin of paraprotein-producing cells (specific B-cell infiltrates) provides an association which is readily comprehensible but rather uncommon. Cutaneous extramedullary plasmacytomas seldom elaborate 'M' components (Canlas, Dillon & Loughrin, 1979), and more generalized lymphoproliferative disorders involving the B-cell series are characterized by the absence of cutaneous involvement. Skin deposits in multiple myeoloma occur only as a terminal event and cutaneous plasma cell infiltrates in Waldenstrom's macroglobulinaemia are exceptionally rare. By contrast, lymphoproliferative disorders involving T cells commonly involve the skin. Indeed, the presence of erythroderma in chronic lymphatic leukaemia indicates that the leukaemia is of T-cell rather than the usual B-cell origin (Lukes et al., 1978). Clearly, T cells are not normally associated with paraproteinaemia, but occasionally monoclonal gammopathies do occur with non B-cell lymphoproliferative disorders, having been recorded twice in Sezary's syndrome (Kovary et al, i<)T]; Joyner et al., 1979). Although this association is not readily explicable, Sezary cells do exhibit helper activity (Broder et al., 1979), so M components may arise as a result of T/B cell interactions (Waldmann,
Modeling robot flexibility for endpoint force control

Dynamic models have been developed in an attempt to match the response of a robot arm. The experimental data show rigid-body and five resonant modes. The frequency response and pole-zero arrays for various models of structural flexibility are compared with the data to evaluate the characteristics of the models, and to provide insight into the nature of the flexibility in the robot. Certain models are better able to depict transmission flexibility white others describe types of structural flexibility. <<ETX>>
Pharmacological evidence of distinct oci‐adrenoceptor subtypes mediating the contraction of human prostatic urethra and peripheral artery

1 The α1‐adrenoceptor subtypes mediating contractions of the smooth muscle in human prostatic urethra and branches of internal iliac artery were characterized in isometric contraction experiments. 2 Phenylephrine produced concentration‐dependent contractions in both the urethra and artery. These responses were competitively inhibited by prazosin, WB4101 and 5‐methyl‐urapidil, and the slopes of Schild plots for all these antagonists were close to unity. 3 The pA2 values for prazosin were not significantly different between the urethra (9.42 ± 0.11; mean ± s.d.) and artery (9.50 ± 0.27), while the pA2 values for WB4101 and 5‐methyl‐urapidil in the human prostatic urethra (8.94 ± 0.19 and 8.42 ± 0.14, respectively) were significantly greater than in the branches of human internal iliac artery (7.94 ± 0.21 and 7.43 ± 0.22, respectively; P < 0.01). 4 Pretreatment with chlorethylclonidine (CEC) at concentrations ranging from 0.1 μm to 100 μm attenuated the maximum contraction to phenylephrine in a concentration‐dependent manner in both the urethra and artery. However, the urethra was significantly less affected by CEC than the artery. The pD'2 values (negative logarithm of the molar concentration of antagonist which reduced the maximum contraction to one half) in the urethra and artery were 4.35 ± 0.27 and 5.20 ± 0.37, respectively (P < 0.01). 5 The present results indicate that there are distinct populations of α1‐adrenoceptor subtypes in the human prostatic urethra and branches of the internal iliac artery. The α1‐adrenoceptors responsible for the contraction of the human internal iliac artery branches are predominantly α1B‐subtype, whereas those in the human prostatic urethra are considered to be not α1B, but α1C or possibly α1A or α1A/D‐subtype.
Linking Job Autonomy and Turnover Intention through Psychological Ownership A Study of Indian Managers

Present paper discusses the role of job autonomy and psychological ownership in affecting turnover intention. A conceptual framework with psychological ownership as a mediator was proposed. The empirical investigation was carried out in an Indian telecom company through a questionnaire survey and it was found that both job autonomy and ownership feelings predicted short term intention to quit and the latter mediated the relationship between the other two variables. Results are discussed and ensuing practical implications are
Web Mining Overview

In the span of a decade, the World Wide Web has been transformed from a tool for information sharing among researchers into an indispensable part of everyday activities. This transformation has been characterized by an explosion of heterogeneous data and information available electronically, as well as increasingly complex applications driving a variety of systems for content management, e-commerce, e-learning, collaboration, and other Web services. This tremendous growth, in turn, has necessitated the development of more intelligent tools for end users as well as information providers in order to more effectively extract relevant information or to discover actionable knowledge. From its very beginning, the potential of extracting valuable knowledge from the Web has been quite evident. Web mining (i.e. the application of data mining techniques to extract knowledge from Web content, structure, and usage) is the collection of technologies to fulfill this potential. In this article, we will summarize briefly each of the three primary areas of Web mining—Web usage mining, Web content mining, and Web structure mining—and discuss some of the primary applications in each area.
The Frequency and the Effects of 21‐Hydroxylase Gene Defects in Congenital Adrenal Hyperplasia Patients

Congenital adrenal hyperplasia (CAH) is a group of genetic endocrine disorders, caused by enzyme deficiencies in the conversion of cholesterol to cortisol. More than 90% of the cases have 21‐hydroxylase deficiency (21‐OHD). The clinical phenotype of the disease is classified as classic, the severe form, and nonclassic, the mild form. In this study, it was planned to characterize the mutations that cause 21‐OHD in Turkish CAH patients by direct sequencing and multiplex ligation‐dependent probe amplification (MLPA) analysis and to investigate the type of CAH (classic or nonclassic type) that these mutations cause. A total of 124 CAH patients with 21‐OHD and 100 healthy volunteers were recruited to the study. Most of the mutations were detected by direct sequencing. Large gene deletions/duplications/conversions were investigated with MLPA analysis. Results were evaluated statistically. At the end of our study, 66 different variations were detected including SNPs and deletions/duplications/conversions. Of these variations, 18 are novel, of which three cause amino acid substitutions. In addition, 15 SNPs which cause amino acid changes were identified among these variations. If similar results are obtained in different populations, these mutations, in particular the novel mutation 711 G>A, may be used as markers for prenatal diagnosis.