Miracle-dz/UniFAR-FTUs huggingface dataset:
Determinanten der Lernerzufriedenheit IT-gestützter Lerndienstleistungen in Betrieb und Hochschule

Ein Qualitatsaspekt betrieblicher IT-gestutzter Lerndienstleistungen liegt in der Teilnehmerzufriedenheit. Deren Determinanten wurden vorwiegend im organisationskulturellen Kontext von Hochschulen evaluiert. Aufgrund der Besonderheiten betrieblichen Lernens, zum Beispiel der Integration in den Arbeitsalltag, ist die Ubertragbarkeit nicht zwangslaufig gegeben. Daher wird in dieser Arbeit eine Studie zu den Einflussfaktoren auf die Nutzerzufriedenheit einer IT-gestutzten Lerndienstleistung bei einem deutschen Technologiekonzern vorgestellt. Das genutzte Modell von Sun et al. zeigt eine hohe Erklarungskraft der Gesamtvarianz der Nutzerzufriedenheit (R²=74%). Im Vergleich zum universitaren Feld ist jedoch unter anderem die Kursflexibilitat deutlich wichtiger als die eigentliche Kursqualitat. Aus den Unterschieden ergeben sich Designimplikationen fur die hochschulische und betriebliche Weiterbildung.
MECHANISM OF ACTION OF ALDOSTERONE WITH PARTICULAR REFERENCE TO (Na+ K)‐ATPase *

Evidence suggests that aldosterone regulates sodium transport through DNAdependent synthesis of RNA and consequently increases the de n o w synthesis of one or more proteins. 1-4 Although no specific aldosterone-induced protein has been isolated or identified, several theories have been advanced to account for the cellular mode of action of this p r ~ t e i n . ~ ? ~ The energy theory states that aldosterone increases the activity of one or several metabolic steps, leading to an increased rate of synthesis of ATP; while the permease theory proposes that aldosterone increases mucosal surface sodium permeability by increasing the synthesis of a carrier protein, thereby increasing the quantity of sodium available to a sodium-limited pumping mechanism. Both the permease and energy theories incorporate the concept of an active sodium pump that is regulated by an increased availability of either sodium ions and/or ATP. The biochemical manifestation of this active sodium pump is (Na + K)-ATPase (ouabain-sensitive, ATP phosphohydrolase, EC 3.6.1.3.). ' The induction of synthesis of (Na + K)-ATPase by aldosterone would constitute a third possible mechanism. Chronic aldosterone treatment results in a significant increase in (Na + K)ATPase activity in the microsomal fraction isolated from adrenalectomized rat However, since changes in electrolyte excretion preceded changes in (Na + K)-ATPase activity following adrenalectomy and aldosterone treatments,8>11*12 it was concluded that the enzyme was not primarily responsible for the antinatriuresis. Since (Na + K)-ATPase is difficult to isolate in the pure form, enzyme preparations employed by previous investigators may not have detected subtle changes in activity due to steroid treatment. In the present investigation, the aldosterone effect was correlated with changes in (Na + K)-ATPase in kidneys of adrenalectomized rats by following the enzyme activity after isolation by differential and sucrose density gradient centrifugation. The involvement of (Na + K)-ATPase in the aldosterone-inductive process was further ascertained by a dual isotopic technique followed by polyacrylamide gel electrophoresis. An aldosterone-induced increase in amino acid incorporation was localized to a particular area of the polyacrylamide gel and subsequently identified as the (Na + K)-ATPase by specifically labeling with (y32P)-ATP and I4C-NEM.
The immune-nutrition interplay in aging – facts and controversies

Nutrition influences immunity in multiple ways, with different nutrients affecting many immune parameters. Aging also affects immunity, making the outcome of the interplay between nutrition, age and immunity complex. Moreover, a particular nutrient may alter the whole immune constellation as deficiency of one nutrient may affect the proper metabolism of another nutrient and elicit a chain reaction of secondary malnutrition. In this article, we review these interactions and the possible mechanisms mediating such relationships.
Polyamine distribution and the potential to form novel polyamines in phytopathogenic agrobacteria

Abstract Polyamines were analyzed in 4 species of genus Agrobacterium . Not only putrescine, spermidine and spermine, but also homospermidine and thermospermine were found in A. tumefaciens, A. radiobacter, A. rubi and A. rhizogenes . Trace amounts of aminopropylhomospermidine were also observed. Norspermidine and norspermine were formed from diamonorpropane added to the medium. Aminopropylcadaverine and its aminopropyl derivative(s) (aminopentylnorspermidine and N , N ′-bis(3-aminopropyl) cadaverine) were produced from the supplemented cadaverine. A strain of A. rhizogenes normally contains only putrescine and homospermidine; no other diamines, triamines and tetraamines were synthesized.
Diets and coexistence in Neomys and Sorex shrews in Białowieża forest, eastern Poland

Prey selection, food niche overlap and resource partitioning were investigated in semi-aquatic Neomys fodiens and Neomys anomalus and terrestrial Sorex araneus and Sorex minutus coexisting in marshland in Biaoowiez ’a Forest, eastern Poland. Evidence of prey selectivity was found but high levels of overlap, particularly in prey size, reflected the abundance of invertebrates in field samples. Despite similarities in diets between all four species, evidence of niche differentiation was found in terms of foraging mode and prey composition. Neomys ate predominantly terrestrial prey but 20% of prey of N. fodiens was aquatic (compared with 11% in N. anomalus), with Asellus being the dominant aquatic prey. Sorex shrews were exclusively terrestrial in foraging mode. All species ate predominantly small prey ( � 5 mm) and these were most abundant in field samples, but small prey were most important for S. minutus. Pairwise comparisons suggested that the most important promoter of resource partitioning was body size, indicating different foraging modes. Food niche overlap was least between species most dissimilar in size. The tiny S. minutus was predominantly an epigeal forager on small Araneae, Opiliones and Coleoptera; the medium-sized S. araneus fed extensively on Lumbricidae and Coleoptera; and the large, semi-aquatic Neomys fed on different amounts of freshwater prey in addition to terrestrial prey. Our results support the prediction that microhabitat selection among these species indicates differentiation in foraging mode.
The post-natal growth of the visceral organs of the lamb Part II. The effect of diet on growth rate, with particular reference to the parts of the alimentary tract

1. A study was made of the effects of diet on the growth of the internal organs, and in particular the four stomachs of lambs. 2. A total of twenty-three lambs was reared from birth on various diets ranging from all milk to small amounts of milk and roughage ad lib. The lambs were slaughtered at various ages and the fresh wet weights of the parts of the alimentary tract and the other internal organs were recorded. 3. The growth rates of the four stomachs were influenced by the plane of nutrition, however, the type rather than the plane of nutrition was more important in determining the weights of the stomachs relative to each other and to live weight. 4. Lambs fed solely milk from birth had the development of their fore-stomachs retarded at about the level found in the 3-week-old grazing lamb. The abomasums of these lambs were abnormally heavy. 5. The rumens and reticulums, which were retarded in their growth by milk feeding, reached normal proportions very quickly once roughage was fed.
Design And Implementation of Group Tourist Monitoring Application With Realtime Database Firebase

The purpose of this study was to determine the stages of creating a group tourist monitoring application using Firebase Realtime Database. Foreign tourists tend to visit Bali in groups and choose tour packages offered by the travel. During a tour at a tourist site, tourists are often too far away from the group and are confused to go back to search for a group or tour leader. One way to overcome this problem is to utilize information technology by building a mobile-based application This application is intended for tourists who visit the place of tour in groups (group tour). Before starting the tour, every tourist will be lent a smart phone. In the smart phone there are android-based applications that send GPS coordinates, timing and identity code of tourists to the cloud server simultaneously. In this application is also given the facility "panic" is a facility that can be used by member group tourist to send a sign of confusion to their tour leader. Tour leader can see all the positions of his group members through the mobile device screen equipped with google map. This application is designed by using UML diagrams and using real-time firebase database. The test results of this application, show tour leader easier to monitor the movement of members of the tour group. Tour group members are also easier to see his own position and see the position of all his group tour. Keywords— group tour monitoring application; real time database firebase application; mobile application;
An Area and Power Efficient Interpolation Scheme Using Variable Current Control for 10-Bit Data Drivers in Mobile Active-Matrix LCDs

This paper presents an area and power efficient interpolation scheme using variable current control (VCC) for 10-bit data drivers in mobile active-matrix LCDs. The VCC interpolation can be embedded in buffer amplifiers as sub-digital-to-analog converters (DACs), reducing the DAC area without requiring additional power and conversion time. Moreover, interpolation errors due to transistor nonlinearity can be compensated through delicate current ratio control, optimizing both accuracy and area efficiency of the high-resolution data driver. The prototype 10-bit data driver with a 6-bit resistor DAC and a 4-bit interpolation sub-DAC occupies the chip area of 460 <inline-formula> <tex-math notation="LaTeX">${\mu }{\text{m}}\,\,{\times }$ </tex-math></inline-formula> 14 <inline-formula> <tex-math notation="LaTeX">${\mu }{\text{m}}$ </tex-math></inline-formula> per channel, which is 10.7% smaller than the conventional 8-bit data driver. The data driver consumes static current of 1 <inline-formula> <tex-math notation="LaTeX">${\mu }\text{A}$ </tex-math></inline-formula>/channel without dissipating additional power for interpolation. The measured integral nonlinearity and differential nonlinearity are 0.4 LSB and 0.7 LSB, respectively. The proposed scheme has competitive performance in terms of driving accuracy, chip size shrinkage, and static power consumption for high-resolution data drivers.
Parameterizing Enterprise WiFi Networks: The Use of Wide Channels

We investigate the joint channel, power, and carrier sensing threshold allocation problem in IEEE 802.11ac enterprise networks in a single 160 MHz band and show that the current practice, which is to use narrower channels at maximum power when the network is dense, yields much worse performance than a solution using the widest possible channel (i.e., 160 MHz) with a much lower power. This finding is consistent with cellular networks which use a reuse factor of one. Based on these insights, we propose and evaluate an algorithm that allocates the widest channel to all Access Points, and finds the appropriate transmission power and carrier sensing threshold for each of them to provide an efficient and fair solution to a managed IEEE 802.11ac enterprise network. The performance gains with respect to the best of the two benchmarks that we consider range from 60% in not too dense deployments to more than 200% in dense deployments.
EFFECTS OF DIET SUPPLEMENTED WITH SOME TRACE ELEMENTS ON THE CONCENTRATION OF THE ELEMENTS AND IMMUNE INDICES IN PIGS

This work aimed to study the effect of organic bound (metallic proteinate) trace elements – Zn, Mn, Cu, Fe, and Se on live weight, concentrations of the elements in the blood serum, as well as phagocytosis, mitogen stimulation of lymphocytes, and the immunogenicity of inactivated oil vaccine against Aujeszky‘s disease. During the experiment, 15weekold pigs were fed a diet with organic mineral admixture at a dose of 1 g per kg of the diet. The experimental and control animals were given inactivated oil vaccine against pseudorabies in the 5th and 7th week of the experiment. Feeding the organic bound trace elements resulted in a favourable effect on weight gain, content of trace elements in the blood, indices of phagocytic activity, and the response of lymphocytes to Aujeszky‘s disease virus.
S6 Kinase: A Compelling Prospect for Therapeutic Interventions

S6 kinase, a member of AGC family of protein kinases and a downstream effector of mTORC1 pathway has over the years found much relevance in maintaining a normal cel lular state by virtue of its established role in regulation of cell growth and proliferation. S6 kinase activity has been linked to different cellular processes like glucose homeostasis, translational and transcriptional regulation. Hence any dysregulation in S6K1 leads to the emergence of various pathological conditions like diabetes, cancer and obesity. It is as such S6 kinase has emerged as a potential target for therapeutic interventions employed in curing such diseases. The Present Chapter reviews the regulation of S6K1, its struc tural organization and functions, besides highlighting its potential to act as an alternative therapeutic target for various cancerous situations exhibiting deranged mTOR signaling so as to overcome the possibility of relapses observed otherwise while using conven - tional drugs
Exposure to Ochratoxin a in Europe: Comparison with a Region of Northern Spain

AbstractHuman exposure to Ochratoxin A (OTA) has been detected in Europe and various other countries by analysing human blood. With the aim of determining if such exposure also occurs in Spain, blood samples were collected from healthy donors and from patients undergoing haemodialysis from a region of northern Spain. OTA is routinely analysed by HPLC with fluorescence detection, after validation of the analytical method. The percentage of positive samples was 53.3% in healthy people (n=75), and 77.8% in patients (n=72) (Detection limit = 0.52 ng/ml of plasma). The mean concentration was 0.71 ng/ml for healthy people, and 1.97 ng/ml for the patients. The difference between the two values was statistically significant (p<0.001). After a multivariate adjustment by the multiple linear regression method, and taking into account potentially interfering effects of age, sex and month of extraction, significantly lower levels where found during the months of June and October. No variation depending on age or sex w.
Federal Information Processing Standard (FIPS) 199, Standards for Security Categorization of Federal Information and Information Systems

A new Federal Information Processing Standard (FIPS), recently approved by the Secretary of Commerce, will help federal agencies protect the informa­ tion and information systems that support their operations and assets. FIPS 199, Standards for Security Cate­ gorization of Federal Information and Information Systems, is an important component of a suite of standards and guidelines that NIST is developing to improve the security in federal infor­ mation systems, including those sys­ tems that are part of the nation's critical infrastructure. (See listing of these planned publications at the end of this bulletin.) FIPS 199 will enable agencies to meet the requirements of the Federal Infor­ mation Security Management Act (FISMA) and improve the security of federal information systems. The secu­ rity standard will also make it possible for federal agencies to establish priori­ ties for protecting their information systems, ranging from very sensitive, mission-critical operations to lower-priority systems performing less criti­ cal operations. Background informa­ tion on NIST's efforts to provide the security standards, guidelines, and technical tools for implementing FISMA is available at: FIPS 199 was approved after an open public review and comment process that included notices published in the Federal Register and posted on the NIST website. Comments and recom­ mendations were received from more than thirty individuals and groups. The new FIPS 199 is available elec­ tronically at: FIPS 199 is effective immediately and applies to: All information within the federal government other than that infor­ mation that has been determined pursuant to Executive Order 12958, as amended by Executive Order 13292, or any predecessor order, or by the Atomic Energy Act of 1954, as amended, to require protection against unauthorized disclosure and is marked to indicate its classified status; and All federal information systems other than those information sys­ tems designated as national security systems as defined in 44 United States Code Section 3542(b)(2). 347), was passed by the one hundred and seventh Congress and signed into law by the President in December 2002. This legislation recognizes the importance of information security to the economic and national security interests of the United States, and tasked NIST with responsibilities for standards and guidelines, including the development of: ❑ Standards to be used by all federal agencies to categorize all informa­ tion and information systems col­ lected or maintained by or on behalf of each agency based on the objec­ tives of providing appropriate levels of information …
Sparse synthesis regularization with deep neural networks

We propose a sparse reconstruction framework for solving inverse problems. Opposed to existing sparse regularization techniques that are based on frame representations, we train an encoder-decoder network by including an ℓ1-penalty. We demonstrate that the trained decoder network allows sparse signal reconstruction using thresholded encoded coefficients without losing much quality of the original image. Using the sparse synthesis prior, we propose minimizing the ℓ1-Tikhonov functional, which is the sum of a data fitting term and the ℓ1-norm of the synthesis coefficients, and show that it provides a regularization method.
The Pharmacokinetics, Optimal Dose and Therapeutic Monitoring of Vancomycin in Severe Burn Patients

Objectives: This paper investigated the pharmacokinetic (PK) change, optimal dose and therapeutic monitoring method of vancomycin in severe burns. Method: This is a retrospective, matched cohort study. Nine burn patients were included, and each individual was matched with a control critically ill patient. Vancomycin concentrations were analyzed using the first order pharmacokinetic principles to calculate elimination rate constant (K), half-life (t1/2), volume distribution (Vd), total body clearance (CLvancomycin) and the 24-hour area under the curve (AUC24 h). Population PK analysis and Monte Carlo simulation was used to investigate optimal dose. Results: The mean burn area of the burn group and age was 60% and 20 years-old respectively. The loading dose and daily maintenance dose was significantly higher in burn group than that in control group. Vancomycin clearance was significantly higher (p<0.05) in burns patients when compared to control patients. CLCr (creatinine clearance) was not significantly correlated to CLvancomycin (vancomycin clearance) in both groups. Ctrough (serum trough concentration) was significantly correlated with AUC24h in the control group (r=0.98, R 2=0.96, p<0.01), but not in the burn group (r=0.63, R2=0.40, P=0.07). Daily dose of 5000 mg of vancomycin could achieve 90% probability of target attainment if target was AUC24h/MIC (minimum inhibitory concentration)>400. Conclusion: Two steady state concentrations but not Ctrough is an appropriate reference for vancomycin therapeutic monitoring. A daily dose of at least 5000 mg is suggested in severe burn patients with normal renal function (CLCr>90 mL/min).
Clinical characteristics and outcomes in patients with lesion-positive transient ischemic attack

*Corresponding author: Dong-Ick Shin Department of Neurology, Chungbuk National University College of Medicine and Medical Research Institute, Chungbuk National University Hospital, Cheongju 28644, Korea Tel: +82-43-269-6372, Fax: +82-43-273-7591, E-mail: sdi007@hanmail.net Transient ischemic attack (TIA) indicates high risk for major stroke and is considered a medical emergency. Diffusion-weighted imaging (DWI) enables detection of acute ischemic lesions. The clinical significance of DWI positive lesions in TIA is obscure and its prevalence, clinical features are not established. Therefore, we performed a clinical, etiological and prognostic analysis through a cross-sectional analysis of 235 TIA patients, grouped according to presence of DWI lesion. Clinical features, underlying risk factors for stroke, outcome and rate of recurrence were analyzed. 3 months follow-up of modified Rankin Scales (mRS) were done with telephone survey. DWI positive lesions were present in 14.0% of patients. Etiological factors significantly associated with DWI lesions in TIA patients were male sex (p = 0.038), stroke history (p = 0.012) and atrial fibrillation (p < 0.001). Presence of at least one medium or high risk of cardioembolism from TOAST classification were not associated with lesions when excluding association to atrial fibrillation (p = 0.108). Clinical features showed no significant difference. Whether the patients had lesion-positive DWI was not related to an increase in mRS score during the hospital stay or at the 3-month follow-up after discharge. Future studies should include multi-center samples with large numbers, considering each unique medical environment. Routine acquisition of follow-up DWI for proper evaluation of the tissue-based definition of TIA should also be considered.
Analog circuit design methodology utilizing a structure of thin BOX FDSOI

: This paper proposes to utilize a structure of thin BOX FDSOI in analog circuit design. The thin BOX layer is utilized to create area e ﬃ cient capacitors. The design experiment shows that the combination of the thin BOX layer capacitor and a metal fringe capacitor improves the capacitance by 92% in comparison with the metal fringe capacitor only. Another advantage of the thin BOX FDSOI technology is the high controllability of the threshold voltages of transistors. As a demonstration of utilizing the advantage in analog circuit design, we designed a PMOS-type Dickson charge pump with dynamic threshold voltage control. The designed charge pump achieves 5.7 times larger output current and 3.5 times higher energy e ﬃ ciency than a conventional charge pump.
Project Studies Beyond the Straitjacket: An Escape Artist’s Manual

This article provides insights into ways in which project studies can be extended to make further impact on and contributions to other research domains, including more general management and organization studies. Inspired by literature on the phenomenology of science, publication practices, logics of research communities, and theory building, we analyze some examples of project studies that reach beyond the project domain. Based on this analysis, we present an “escape artist’s manual” consisting of strategies and practices for how researchers could think about and design project studies to enable contributions beyond the home domain.
Analysis of Phase-Extraction Neural Network (PhENN) performance for lensless quantitative phase imaging

PhENN is a convolutional deep neural network that reconstructs quantitative phase images from diffracted intensity measurements some distance away from the phase objects. PhENN is trained on known phase-intensity pairs created from a particular database (e.g. ImageNet) but then found to perform well on objects created from other databases (e.g. Faces-LFW, MNIST, etc.). In this paper, we analyze the dependence of quantitative phase measurement quality on PhENN's architecture and the layout of the lensless imaging system, in particular, the number of layers (depth), the size of the innermost layer (waist size), the presence or absence of skip connections, the choice of training loss function and the free space propagation distance.