Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of fermentation of soybean meal with varying protein solubility on ileal digestibility of nutrients in growing pigs

Apparent ileal digestibility and standardised ileal digestibility of energy, dry matter, nitrogen and amino acids were evaluated in five cannulated [(Landrace × Yorkshire) × Duroc)] barrows with an initial bodyweight of 27.1 ± 0.58 kg in a 5 × 5 Latin square design. Pigs were fed unfermented soybean meal (USM) as control and fermented soybean meal A, B and C (FSMA, FSMB and FSMC, respectively), with 52.4%, 62.0% and 71.8% protein solubility, respectively, and a nitrogen-free diet. The nitrogen-free diet was used to determine basal endogenous losses of crude protein and amino acids. The apparent ileal digestibility of dry matter and nitrogen was greater (P < 0.05) in FMSC and tended to improve in FSMA and FSMB compared with the control. The apparent ileal digestibility of isoleucine, phenylalanine and valine was greater in all fermented soybean meal whereas that of lysine was greater (P < 0.05) in FSMC compared with USM. Likewise, the apparent ileal digestibility of aspartic acid and proline was greater (P < 0.05) in FSMA and FSMC. The standardised ileal digestibility of crude protein and lysine was higher (P < 0.05) in FSMC and tended to improve in FSMA and FSMB whereas the standardised ileal digestibility of isoleucine was higher (P < 0.05) in FSMA, FSMB and FSMC compared with USM. In conclusion, fermentation of soybean meal showed better digestibility compared with USM regardless of its protein solubility values.
P14.124 EORTC 1709/CCTG CE.8: A phase III trial of marizomib in combination with standard temozolomide-based radiochemotherapy versus standard temozolomide-based radiochemotherapy alone in patients with newly diagnosed glioblastoma

The standard of care for patients with newly diagnosed glioblastoma includes maximal debulking surgery followed by radiotherapy (RT), and concomitant as well as maintenance therapy with the alkylating agent, temozolomide (TMZ). However, the prognosis remains poor and novel treatment strategies are urgently needed. Targeting the proteasome has been considered a promising anti-cancer approach for several years. Marizomib is a novel, irreversible and pan-proteasome inhibitor, which crosses the blood-brain barrier and has been assessed in phase I trials in patients with newly diagnosed or recurrent glioblastoma. EORTC 1709/CCTG CE.8 is a randomized, controlled, open label phase III superiority trial. Patients with histologically confirmed newly diagnosed glioblastoma and a performance status >70 are eligible. Patients are randomized in a 1:1 ratio to receive standard of care (TMZ/RT→TMZ) alone or TMZ/RT→TMZ plus marizomib. The study aims at enrolling 750 patients. Stratification factors include study site, age, performance status and extent of resection. The primary objective of this trial is to compare overall survival in patients receiving marizomib in addition to standard of care with those receiving standard treatment only. The testing strategy specifies the determination of this objective in the intent-to-treat population as well as the subgroup of patients with MGMT-unmethylated tumors. Secondary endpoints include progression-free survival, safety, neurocognitive function and quality of life. A translational research program has been set up. The study will be activated at approximately 50 EORTC sites across Europe, 25 sites in Canada and additional sites in the US. Patient recruitment started in June 2018 and as of April 29, 2019, a total of 164 patients have been randomized. An update on the enrolment status will be provided at the EANO meeting. ClinicalTrials.gov Identifier: NCT03345095
SOFT WINGED FLOWER BEETLES (COLEOPTERA: MALACHIIDAE) IN EGYPT

The distribution of the known species of the Egyptian malachiid fauna is analysed and their recent taxonomic status is as- sessed. Various sources indicated the existence in Egypt of 43 malachiid species belonging to 17 genera in one subfamily. Repre- sentatives of 23 species were collected in the course of the current project. The remaining 20 species have been included in our list on the basis of their presence in Egyptian insect collections.
PENGARUH PENYUNTIKAN OKSITOSIN SEBELUM INSEMINASI PADA BABI TERHADAP PERSENTASE KEBUNTINGAN DAN JUMLAH ANAK PER KELAHIRAN

Penelitian ini bertujuan untuk mengetahui pengaruh penyuntikan oksitosin sebelum inseminasi pada babi terhadap angka kebuntingan dan jumlah anak per kelahiran Penelitian ini menggunakan rancangan acak lengkap dengan dua kelompok perlakuan. Masing-masing kelompok terdiri dari 5 ekor induk babi landrace induk muda (melahirkan antara 3-4 kali dengan umur kira-kira 3 tahun) yang sedang menyusui dan siap untuk disapih dikandangkan secara individu. Kelompok I (T0) Sebelum diinseminasi terlebih dahulu disuntik dengan menggunakan NaCl 0,9% sebanyak 1 ml secara intra muskular sebagai flasebo. Pada kelompok II (T1) Sebelum diinseminasi terlebih dahulu disuntik dengan menggunakan hormon oksitosin 10 IU (1 ml) secara intra muskular. Pengamatan dilakukan terhadap angka kebuntingan dengan cara mengamati munculnya estrus 21 hari berikutnya, sedangkan jumlah anak perkelahiran diamati dengan menghitung jumlah anak yang lahir pada saat induk melahirkan. Data yang diperoleh dianalisis dengan uji t tidak berpasangan. Hasil penelitian menunjukkan penyuntikan oksitosin sebelum inseminasi pada babi tidak berpengaruh terhadap angka kebuntingan (P>0,05) dan berpengaruh nyata (P<0,05) meningkatkan jumlah anak per kelahiran. Kata kunci : oksitosin, babi, angka kebuntingan, jumlah anak per kelahiran. A study was carried out to determine the effect of oxytocin prior to artificial insemination on pregnancy rate and letter size in pigs. A total of 10 pigs were allocated to a treated group (T1) and control group (T0). Each group consisted of 5 animals. Animal in the treated groups received on injection 10 IU Oxytocin prior to artificial insemination. Animal in the control group received saline at 1 ml. The pigs were injected by intramuscularly in the neck. Pregnancy rate were monitored and litter size were determined for all animals. The data were analised by using t test. The result of study showed that the litter size of oxytocin treated animals was significantly (p<0,05) higher than that control group, but not significant on pregnancy rate.
Small Ruminant Lenti-virus infection in imported sheep in Greece

During the last years, a large number of Assaf-E sheep have been brought into Greece from Spain. In total, 57 randomly selected Assaf-E sheep purchased from Spain to five 5 different farms in Greece were examined serologically on arrival for Small Ruminant Lentiviruses . Of these, 25 animals were found to be seropositive against Small Ruminant Lentiviruses . Taking into account the above findings, we suggest a more strict legislation at the sheep sales.
Remotely-delivered immunocontraception in feral horses.

Reducing fertility among free-roaming feral horses (Equus caballus) has been the goal of numerous studies over the past 16 years (Kirkpatrick et al. 1982, Goodloe et al. 1988, Plotka et al. 1989). Initial experiments by Kirkpatrick et al. (1982) and Turner and Kirkpatrick (1982) resulted in an 83% decrease in foaling among feral mares bred by stallions which were first immobilized and then treated with injectable microencapsulated testosterone propionate (mTP). Although the treatment decreased sperm count and motility, the high costs and the stress caused by immobilization or capture made it clear that the contraceptive agent needed to be delivered remotely. In a second study Kirkpatrick and Turner (unpublished data) demonstrated the pharmacological effectiveness of mTP in stallions, but difficulty was encountered in remotely delivering a sufficient mass of the steroid. Recently, attention has turned to contraception in the feral mare. Experiments with ethinylestradiol-progesterone Silastic? implants (Vevea et al. 1987, Plotka et al. 1988, Plotka et al. 1989) showed pharmacological promise, but the technique required capture, restraint, and field surgery to place the implants intraperitoneally. An alternative to steroid-induced fertility control is immunocontraception. A conjugated form of luteinizing hormone releasing hormone (LHRH) has been used successfully to raise antibodies in captive feral mares (Goodloe et al. 1988), and solubilized porcine zonae pellucidae (PZP) injections inhibited fertility in 13 of 14 domestic and captive feral mares (Liu et al. 1989). The success of the PZP vaccine in suppressing fertility is based on its ability to inhibit fertilization or possibly implantation (Sacco et al. 1984). The porcine zona pellucida consists of 3 glycoproteins. One of those, ZP3, is the receptor molecule for sperm surface molecules (Florman and Wassarman 1985). Equine antibodies raised against PZP are thought to block the sperm receptor sites on the equine ovum, thereby preventing fertilization (Liu et al. 1989). To date, PZP has been used to successfully inhibit fertility in a number of mammals, including 5 species of nonhuman primates and in vitro fertilization in humans (Sacco 1987). The objectives of this study were to (a) determine the effectiveness of remote delivery, (b) test the contraceptive effectiveness of a PZP vaccine in free-roaming feral mares, (c) determine the contraceptive effectiveness of the vaccine in pregnant and nonpregnant mares, and (d) evaluate the safety of the vaccine for use in pregnant mares.
Draft genome sequence of lytic bacteriophage KP1 infecting bacterial pathogen Klebsiella pneumoniae

Klebsiella pneumoniae is a Gram-negative, rod-shape bacterium causing disease in human and animal lungs. K. pneumoniae has been often found to gain antimicrobial resistance, thus it has been difficult to treat K. pneumoniae infection with antibiotics. For such infection, bacteriophage can provide an alternative approach for pathogenic bacterial infection with antimicrobial resistance, because of its sensitivity and specificity to the host bacteria. Bacteriophage KP1 was isolated in sewage and showed specific infectivity to K. pneumoniae . Here, we report the draft genome sequence of Klebsiella pneumoniae phage KP1. The draft genome of KP1 is 167,989 bp long, and the G + C content is 39.6%. The genome has 295 predicted ORFs and 14 tRNA genes. In addition, it encodes various enzymes which involve in lysis of the host cell such as lysozyme and holin.
Fat metabolism and turnover

This chapter will emphasize the metabolism of non-esterified fatty acids (NEFA) although some discussion will relate to triglyceride (TAG) and ketone bodies. Plasma NEFA are a highly labile form of Lipid that are transported between tissues in the circulation bound to albumin. Although plasma NEFA are only a small proportion (5%) of total plasma lipid they represent an important source of oxidizable energy, particularly during periods of negative energy balance or when there is an acute need for energy such as during exercise. This chapter will deal with the composition and sources of plasma NEFA, the fate of NEFA during different physiological states as well as the acute and chronic regulation of NEFA metabolism. In addition, this chapter will cover methodology and principles of NEFA metabolism and also describe adaptations to different physiological states. Although these areas have been covered in several reviews (Lindsay, 1975; Emery, 1979; Annison. 1984; Wiseman. 1984; Chilliard et al., 2000), this chapter will emphasize the quantitative aspects of NEFA metabolism.
CURTAILING CYBERCRIME IN NIGERIA: APPLICABLE LAWS AND DERIVABLE SOURCES

The innovation in computer, information communication infrastructure and internet, cuts across every human endeavour in Nigeria. It has also created avenue for miscreants to engage in cybercriminality against cyber citizens. Since the economic gains emanating from the use of the computer, internet and other digital paraphernalia to perpetrate cybercrime by cybercriminals outweigh the consequences of their act, in the event they are caught, they are likely to continue in their illegality. This is further exacerbated by the anonymity of the internet; lucrative nature and awareness of the subject area; greed and potential targets increment; the fact that it requires smaller investment to start and that it can be carried out in various locations without any iota of geographical constraints. The proliferation of cybercrimes in Nigeria has generated debates in the literature as to whether or not there exists legal framework for effective and efficient investigation and prosecution of cybercrimes in Nigeria. In this regard, this paper examines the literature and consequently, enlist applicable laws and derivable sources that will generally be handy to stakeholders; law enforcement agents; prosecutors; counsel to eradicate cybercrime in Nigeria.
Stock Price Prediction Using RNN and LSTM

Prediction of stock market has been an attractive topic to the stockbrokers. In stock market the decision on when buying or selling stock is important in order to achieve profit. There are number of techniques that can be used to help investors in order to make a decision for financial gain. In this research work we have proposed a prediction algorithm that will give the relation between the dependent factor like price and independent factors like opening price, closing price, high value of stock, low value of stock and volume of stocks bought. In this research, we have explained development of stock price prediction with the use of deep learning algorithm. In this work, we are going to use different deep learning architecture for the price prediction of BSE listed company and compares their performance. Here we had used LSTM (Long short-term memory) and RNN (Recurrent neural network) algorithms. We had shown comparative study of this two deep learning algorithm. Study shows that RNN gives better performance than LSTM. Accuracy of LSTM is 87% and accuracy of RNN is 89%. Cite this Article Janki Patel, Miral Patel, Mittal Darji. Stock Price Prediction Using RNN and LSTM. Journal of Open Source Developments . 2018; 5(3): 26–34p.
Exigências nutricionais de treonina digestível para poedeiras semipesadas no segundo ciclo de produção

The objective of this work is to determine the nutritional requirement of digestible threonine for brownegg laying hens between 79 to 95 weeks of age. For this experiment, 180 commercial Lohmann Brown laying hens were used, distributed in five digestible threonine levels (0.380; 0.413; 0.446; 0.479 and 0.512%), each one with six replicates and six hens/replicate. It was observed a quadratic effect of threonine levels on the feed intake, egg mass conversions, egg dozen conversions, egg production, egg weight, and egg mass. The digestible threonine intake increased linearly in function of diet threonine levels. It was not observed effect of diet threonine levels for weight gain, yolk index, albumen index, shell percentage, yolk percentage and albumen percentage, except for the Haugh units, which increased in a quadratic way according to digestible threonine levels in the feed. Regarded to the food conversion per egg dozen, the requirement of digestible threonine for commercial hens in the period between 79 to 95 weeks of age is 0.467%, which corresponds to an intake of 462 mg threonine/hen/day.
Nutritional evaluation of poultry by-product meal in broiler chickens.

This experiment was conducted to determine the apparent protein digestibility, metabolizable energy (AME) and metabolizable energy correction of zero nitrotion (AMEn) of poultry by-product meal (PBPM) from two industrial poultry slaughter houses on Ross 308 male broiler chickens. The experiment consisted of seven dietary treatments and three replicates per treatment with three broiler chickens male per replicate in a compeletely randomized design. Dietary treatments consisted of a control cornsoybean diet, and levels 3, 6 and 9% PBPM produced by slaughter house 1 and levels 3, 6 and 9% PBPM produced by slaughter house 2. Chromic oxide was added to the experimental diets as indigestible marker. Apparent protein digestibility, AME and AMEn of each diets were determined with two methods of sample collection of ileum and excreta in 21-28d of age. Use of PBPM had no significant effect on performance of broiler chicks during period of digestibility experiments (P>0.05). Results indicated that there were significant differences in apparent protein digestibility, AME and AMEn in PBPM groups vs control group by excreta sampling procedure (P<0.05). The apparent protein digestibility, AME and AMEn based on ileum sampling procedure significantly decreased in level 9%PBPM slaughter house 2 (P<0.05). The site of measurement had no significant effect on protein digestibility AME and AMEn among experimental treatments (P>0.05), but ileal protein digestibility was significantly greater than excreta as concern the two sampling methods (P<0.05).
Immunological and Molecular Aspects of Bacterial Virulence

Pathogenic Bacteria in Context: An Overview. HOST DEFENCE: THE IMMUNE SYSTEM. Non-Clonal Recognition and Immunomodulation. Clonal Recognition: Antibodies and T-Cell Receptors. Clearance Mechanisms: Complement, Phagocytosis and Cell Mediated Cytotoxicity. THE BACTERIAL INVASION. Bacterial Nutrition: The Host as a Substrate. Bacterial Exotoxins Which Act Inside Host Cells. Bacterial Surface Molecules and Virulence. Intracellular Invasion, Survival and Growth. Genetic Variation and Regulation of Virulence Determinants. Appendix. Index.
Hablemos de nuestro trabajo. Riesgos psicosociales en entornos de trabajo de extensionistas agropecuarios de la Argentina

Evaluamos la exposicion a factores de riesgo psicosocial en agentes de los Servicios de Extension Agropecuaria en Argentina. Encuestamos 152 extensionistas de dos organizaciones y diversas provincias argentinas con el instrumento CoPsoQ-ISTAS 21 y debatimos los resultados con 67 de estos profesionales durante un curso de posgrado de la Maestria PLIDER. Este curso funciono para los extensionistas como una Clinica de la actividad, permitiendoles gestionar sus propios recursos ante el stress sostenido provocado por la exposicion a los factores de riesgo. La investigacion se reforzo con 15 entrevistas en profundidad.Los resultados muestran una fuerte exposicion a los factores de riesgo psicosocial donde aquellas causas que prevalecen derivan de la forma de organizacion del trabajo en cada institucion de pertenencia, el elevado componente emocional del rol laboral, y la diferencia entre hombres y mujeres en cuanto a la autonomia en su realizacion, las exigencias inherentes a la posicion de enlace organizacional, el conflicto por la ambiguedad del rol y su carga mental.
Studies on the biology of environmentally persistent Listeria monocytogenes strains

Listeria monocytogenes is a saprophytic bacterium capable of causing serious foodborne human disease. Persistent contamination by L. monocytogenes represents a threat to public health and has serious economic implications for the contaminated facility. Actions taken to minimise contamination of the factory environment/food products are expected to cause physiological stress to L. monocytogenes, and it has been shown that the ability to resist stress, and therefore persist within an environment, can augment L. monocytogenes virulence. In this dissertation, the hypothesis that physiological adjustment by L. monocytogenes facilitates persistent food factory contamination, and that some strains are better able to implement this shift than others, is assessed. Isolates recovered from a food factory were characterised using multilocus sequence typing, and attributes of this group thought to enable persistent environmental contamination were compared. These included biofilm production and the mechanisms affording alkaline stress adaptation. Biofilm production by L. monocytogenes strains isolated from multiple environments, including a food processing factory and environmentally persistent/sporadic factory isolates, due to temperature and pH stress was assessed using a colourimetric assay and scanning electron microscopy. A temperature-specific biofilm production response was observed as was environmentally induced homogeneous biofilm production by non-clonal L. monocytogenes strains recovered from the same environment. Observations provided evidence for distinct, inducible biofilm production. Importantly, it was concluded that biofilm production alone does not determine the persistent L. monocytogenes phenotype. To investigate if stress adaptation contributes to persistent factory contamination, protein expression by alkaline adapted persistent and sporadic factory contaminants was compared using high resolution proteomics. Additionally, a well characterised L. monocytogenes strain was studied at pH 9.0, with emphasis on the role of cell membrane proteins. Qualitative and relative protein abundances were compared through functional ontology and determination of spectral abundances. Findings suggested alkaline adaptation involves cytoplasmic acidification by surrogate proton sources, an energy metabolism shift, stabilisation of cellular processes and cell wall modification. This was most pronounced in exponential phase. Although more pronounced in persistent strains, no difference in the mechanisms supporting alkaline tolerance was evident between strains. The results of this dissertation support the notion that exposure to environmental stresses within food facilities can induce or select the persistent L. monocytogenes phenotype. This may be caused by the complexity of operations within these facilities, leading to concentration fluxes of cleansing/sanitising agents and other growth limiting challenges, subjecting the strains to varying forms of sublethal stress.
POSTAWY WOBEC ZARZĄDZANIA WIEDZĄ W OTWARTYCH INNOWACJACH

Celem artykułu jest przedstawienie autorskiej klasyfikacji modelowych postaw wobec zarządzania wiedzą w otwartych innowacjach oraz jej empirycznej weryfikacji na rynku polskim. W badaniach empirycznych wykorzystano metodę standaryzowanych telefonicznych wywiadów kwestionariuszowych ze wspomaganiem komputerowym (CATI). Autorzy, biorąc pod uwagę poziom dzielenia się i poziom ochrony wiedzy, zidentyfikowali cztery modelowe postawy wobec zarządzania wiedzą w otwartych innowacjach: profesjonalisty (eksperta) wiedzy, władcy wiedzy, dyfuzora wiedzy i dyletant wiedzy. W Polsce najszerzej rozpowszechnioną postawą jest postawa eksperta wiedzy, zdecydowanie rzadziej przedsiębiorstwa przyjmują postawę władcy wiedzy i dyfuzora wiedzy. Przedsiębiorstwa w Polsce nie przyjmują postawy dyletanta wiedzy.
Digestibilidade pré-cecal diurna e noturna em equinos fistulados alimentados com diferentes concentrados

O objetivo deste trabalho foi determinar as possiveis diferencas entre periodos diurno e noturno dos coeficientes de digestibilidade parcial pre-cecal da materia seca, materia orgânica, amido, proteina bruta, fibra em detergente acido e fibra em detergente neutro de diferentes dietas formuladas com concentrados energeticos a base de milho, aveia, sorgo e milho/aveia 50/50%. Foram utilizados quatro cavalos ileo-fistulados com 36±4 meses de idade, mesticos, machos, castrados, com peso medio de 308±32kg. O delineamento experimental foi um quadrado latino 4X4 (quatro tratamentos, quatro periodos). Houve diferencas entre os periodos diurno e noturno nas fracoes da materia seca, materia orgânica, amido, fibra em detergente acido e fibra em detergente neutro no tratamento a base de milho, nas fracoes fibra em detergente acido e fibra em detergente neutro no tratamento com aveia, e na fibra em detergente acido dos tratamentos com sorgo e milho/aveia 50/50%.