Miracle-dz/UniFAR-FTUs huggingface dataset:
Association between FokI Vitamin D Receptor Gene Polymorphism and Visceral Obesity in Patients with Type 2 Diabetes: A Single-Blinded Randomised Clinical Trial

Received: 11/08/2018 Revised: 03/08/2018 Accepted: 17/08/2018 Background: Role of genetic variants on the effect of vitamin D on adiposity measures is still unclear. This study aimed to investigate the effect of vitamin D on visceral adiposity using intake of vitamin D fortified doogh. Methods: This was a single-blinded randomised clinical trial which seventy type 2 diabetic Iranian subjects were randomly allocated to two groups of receiving plain Doogh (PD; n 32, containing 170 mg Ca and no vitamin D/250 ml) or vitamin D3-fortified Doogh (FD; n 38, containing 170 mg Ca and 12•5 μg/250 ml) twice a day for 3 months. Serum 25-hydroxyvitamin D (25(OH)D, anthropometric measures, body composition, glycaemic status and visceral obesity indicators assessed twice before and after the intervention. Genotyping was conducted for FokI single nucleotide polymorphisms (SNPs) of the VDR gene by polymerase chain reaction. Results: Serum 25(OH)D (P<0.001) was increased in FD compared to PD and waist circumference (P= 0.022), fat mass (P<0.001), visceral adipose tissue (P<0.001), and trunk fat (P<0.001) were decreased after 3-month intervention. Analysis of FOK-1 genotyping was showed significant change for 25(OH)D (P=0.03), FSG (P=0.036), HbA1c (P=0.003), waist circumference (P=0.045), waist: hip ratio (P=0.04), fat mass (P=0.016), visceral adipose tissue (P=0.024), and Truncal fat (P=0.004) after Tukey’s post hoc analysis. Conclusion: In conclusion, FD compared to PD could increase serum 25(OH)D and improve glyceamic, anthropometric, and visceral obesity indicators. Moreover, significant differences was seen between FOK-1 (FF, Ff, and ff) genotypic groups for 25(OH)D, FSG, HbA1c, waist circumference, waist: hip ratio, fat mass, visceral adipose tissue, and Truncal fat.
DETERMINATION OF THE PHYTOCHEMICAL CONSTITUENTS AND THE ANTIBACTERIAL ACTIVITY OF THE ROOT BARK EXTRACT OF NEOCARYA MACROPHYLLA (SABINE) PRANCE, AGAINST KLEBSIELLA PNEUMONIAE, AN EAR INFECTION-CAUSING PATHOGEN

Neocarya macrophylla root bark extractis a potential source of novel antimicrobial compounds, especially against Klebsiella pneumoniae, a bacterial pathogens. N. macrophylla is a medicinal plant commonly used in traditional medicine in Northern Nigeria to treat asthma, skin infections, treatment of wounds, pulmonary troubles, dysentery, inflammations and it is also used for the treatment of eye and ear infections.The susceptibility test results showed inhibition range of 15, 13, 11, 13 and 14mm for the NM, NM4, NM3, NM2 and NM1 respectively against test organism at 50mg/mL, and 09, 11, 09, 12 and 13mm for NM, NM4, NM3, NM2 and NM1 respectively at 25mg/mL, and finally -, 09, -, 09 and 09mm for NM, NM4, NM3, NM2 and NM1 respectively at 12.5mg/mL. This indicates NM, NM1, NM2 and NM4 to be the most active fractions against the organism at 50mg/mL in a respective manner and the least active fraction is NM3 at 25mg/mL, while fractions NM1, NM2 and NM4 showed no activity at 12.5mg/mL against the test organism. The test results indicated that root back extract of N. macrophylla has antibacterial potency and could be used as an alternative antimicrobial therapy
Review and Prospect of Flexible Loads for Participating in Frequency Regulation

The rapidly increasing renewable energy sources (RESs) in the power system bring a large number of disturbances due to the intermittent and random characteristics of power generation. At the same time, most of the RES units are composed of power electronic devices, which can reduce the system inertia and impact the stable operation of the power system. Therefore, more operating reserve resources are required to participate in the rapid regulation in the power system with a high proportion of RES. The rapid development of information and communication technologies make it easier and lower cost to control flexible loads. Based on the new network resources, for example, 5G, flexible loads can be regulated rapidly to participate in power system frequency control. In this paper, the models, categories, and functions of typical flexible loads are analyzed. Then, the research status of various flexible loads for participating in frequency regulation (FR) is combed in detail. On this basis, the advantages and disadvantages of various load control methods and their application scenarios are discussed. Finally, the development prospects of flexible loads for FR are proposed, so as to provide references for practical application.
Viral diseases: DNA viruses

The disease is caused by members of the gammaherpesviruses group. Alcelaphine herpesvirus-1 (AHV-1), carried asymptomatically by the wildebeest (Connochaetes taurinus) in Africa, has been diagnosed in disease outbreaks in zoos in North America. Ovine herpesvirus-2 (OHV-2) is carried asymptomatically by sheep (117). A third, as yet unnamed virus, has been detected in an outbreak of MCF in white-tailed deer (Odocoileus virginianus) (80).
ENGENDERING TECHNOLOGIES OF COMMUNICATION: THE APPROPRIATION OF MOBILE PHONE TECHNOLOGY BY RURAL WOMEN IN FOOD PRODUCTION IN WESTERN KENYA SINCE 2007

Agriculture plays a vital role in the economic growth of Global South countries, although the sector has been underperforming as compared to those in developed countries for decades. For an increase in production, there is a need to adopt improved agricultural technologies. Public sector programmes are adopting technology by providing agricultural extension services to overcome information related barriers. While such programmes have been generally criticized because of their limited scale, sustainability and impact, the rapid spread of mobile phone coverage in Global South countries provide a unique opportunity to aid the adoption of technology via information and communication technology (ICT)-based extension programs. The study delineates plausible mechanism (internet and mobile money transfers) through which mobile phones could aid the provision and adoption of agricultural information and extension services in Western Kenya. The purposive target population comprised of rural women, development partners and groups from social welfare and civil society in Western Kenya. Key Informant Interviews were used through personal interviews to gather primary data and Kenya National Archives provided both primary and secondary data. Institutional libraries in Kenya were also instrumental in providing secondary information for the study. Data was analyzed qualitatively using thematic and content analysis approach. Historical research design was employed in analyzing the history of the adoption and usage of mobile phone technology by rural women with regard to food production in Western Kenya. The study noted that women in rural part of Western Kenya either remain not aware of updated agricultural practices or receive second-hand information from their male farmer peers who access modern agricultural information and services with the aid of mobile phones. Subsequently, rural women who are subscribed to mobile phones gain from using this technology as their principal means of updating their knowledge about the new agricultural interventions. Based on the results of the findings, considering the global growing trend of female mobile subscribers, and appreciating the vital position of rural women in the food production sector, it is fundamental that the prospects for exploiting this technology to disseminate mobile internet services including access to mobile money transfer services amongst rural women must be studied. GSJ: Volume 8, Issue 3, March 2020 ISSN 2320-9186 1264 GSJ© 2020 www.globalscientificjournal. com
Are Cattle Genetics Priced to Reflect Carcass Value

The impact of breed on carcass characteristics in various breeds of cattle has been well documented. This paper attaches these differences in breed characteristics to end revenue via different breed and breed combinations, percentage of Angus in pedigree, and purebred status. We find that while the genetics of many breeds is priced roughly in line with its value, some breeds are overpriced or underpriced by enough to significantly improve a cattle operation’s profitability. We find that, relative to a pure Angus base, most breeds are less profitable in terms of carcass revenue per hundredweight.
Sustainable Construction Supplier Selection by a Multiple Criteria Decision-making Method with Hesitant Linguistic Information

Within the context of resource constraints and ecological environment imbalance, the adoption of green suppliers can help construction enterprises achieve sustainable development and improve their competitiveness. The selection of sustainable construction suppliers is a multi-criteria decision-making problem since multiple factors should be considered. The increasingly complex decision-making environment makes it difficult for evaluators to give accurate evaluation values. In this regard, the hesitant fuzzy linguistic term set is a qualitative evaluation tool to represent the comprehensive linguistic evaluation values of experts by considering the hesitancy behaviors of experts. In this paper, a scientific multi-criteria decision-making model based on the improved Stepwise Weight Assessment Ratio Analysis (SWARA) method and the double normalizationbased multi-aggregation (DNMA) method in the hesitant fuzzy linguistic environment is proposed. A new distance measure is proposed to measure the differences between hesitant fuzzy linguistic term sets with different lengths without changing the original evaluation information of experts. The proposed distance measure is applied to the proposed multi-criteria decision-making model. After improving the calculation steps of the traditional SWARA method, we can determine the weights of criteria effectively through our proposed model. To verify the applicability of the proposed method, we implement it to select sustainable building suppliers. The effectiveness of the method is verified by sensitivity analysis. We also compare the results obtained by our method and those derived by the Weight Aggregated Sum Product ASsessment (WASPAS) method and the Technique for Order Preference by Similarity to an Ideal Solution (TOPSIS) method. The proposed method have a strong applicability to solve the sustainability-related decision problems given that it can effectively determine the weights of criteria and flexibly meet the needs of decision-makers by adjusting the coefficient.
A questionnaire based comparative study on dry lab versus wet lab among second year medical undergraduates in a tertiary care hospital of Bihar

Background: Objective of the study was to identify whether there is any benefit of integrating dry lab/computer assisted lab (CAL) tool with conventional teaching/wet lab in experimental part of pharmacology. Methods: A questionnaire based study was conducted among 158 second year medical undergraduates in the department of pharmacology. The questionnaire was distributed among students with proper prior instructions in practical class. Students willing to participate in the study were included. Results: Total 94.9% were in the favour of replacing conventional teaching with CAL lab learning, 74.7% felt conventional lab to be more complex, 92.4% has the opinion of CAL lab result has less error along with that majority student felt it to be less time consuming, need lesser assistance and enhance learning. 67% student also felt real experimentation can’t be learned by CAL tool and 83.5% have their thought that CAL lab can never help them in exercising real experiment. Conclusions: Although there is no substitution of conventional teaching methods, in this new era of information and technology CAL lab can be the saviour to students in making better understanding and enhancing the performance without help of experimental animals.
Detection of Programming Plagiarism in Computing Education: A Systematic Mapping Study

The programming plagiarism is increasingly a problem in computing education, and the proposed solutions for this growing concern rely on automatic detectors. The usage of the automatic tools for this purpose can provide benefits in education for professors and instructors of programming assignments, besides, to avoid the lack of essential skills from the students since they compromise their programming logic by plagiarizing. This paper performs a systematic mapping study aligned with a snowballing technique to analyzes the existing solutions for this domain. As contributions, tendencies, as well as information analysis, are provided to guide new proposals of solutions.
Animal Models Used in Testing the Biocompatibility of the Dental Implant – A Review

In order to investigate the interaction between the bone and the dental implant, in vivo testsare performed in accordance with the biocompatibility requirements. As in vitro tests do not provide sufficient data on the quality of the implants, the animal models are used because they allow a complete assessment of all the factors involved in the osseointegration process. The aim of the paper is to provide data on the bone structure of animal species involved in dental research, highlighting the complexity of bone structure and osseointegration depending on the species. At the same time, the importance of selecting animal models is emphasized, in order to obtain the most accurate data for the development of dental implants and their use in humans. Following the research, essential data were obtained that helped to synthesize the bone characteristics of animals such as rats, rabbits, pigs, sheep or goats and relate them to the human bone skeleton. These data are useful in choosing an animal model when testing a new dental implant.
An Approach to Direct Determination of Protein Dynamics from 15N NMR Relaxation at Multiple Fields, Independent of Variable 15N Chemical Shift Anisotropy and Chemical Exchange Contributions

An approach to protein dynamics analysis from 15N relaxation data is demonstrated, based on multiple-field relaxation data. This provides a direct, residue-specific determination of both the spectral density components, the 15N chemical shift anisotropy (CSA) and the conformational exchange contribution to the 15N line width. Measurements of R1, R2, and 15N{1H} NOE are used. The approach is free from any assumption about the values of the CSA or of the conformational exchange. Using this approach, the spectral densities, the values of 15N CSA, and the conformational exchange contribution to the 15N line width are directly determined from the relaxation data for human ubiquitin, collected at 360, 500, and 600 MHz. The spectral densities are analyzed in terms of the order parameter and the correlation time of local motion, using an axially symmetric overall rotational diffusion model. The residue-specific values of 15N CSA and the spectral densities obtained using this approach are in agreement with those d.
Robotic or laparoscopic surgery for rectal cancer - which is the best answer? A comprehensive review of oncological outcomes

Treatment of rectal cancer is ever evolving with the introduction of newer surgical technologies and multimodal treatment approach. The literature evaluating the various surgical treatment options with regards to operative and nonoperative outcomes is abundant. This is a comprehensive review focused on oncological outcomes of rectal cancer resection performed robotically or laparoscopically. Based on the current literature available, there is no significant difference in total mesorectal excision completeness, lymph node harvest, positive circumferential resection margin, or proximal resection margin between robotic and laparoscopic approaches for rectal resection. Selection of surgical approach should not be based on pathological outcomes as they are equivalent.
State-specific multireference complete-active-space coupled-cluster approach versus other quantum chemical methods: dissociation of the N2 molecule

A comprehensive comparison of different quantum-chemical methods applied to calculate the N2 ground state potential energy curve is presented. In the comparison we highlight the multireference state-specific (MRSS) coupled-cluster (CC) approach with the complete-active-space (CAS) reference and with single and double excitations from all reference determinants in the CC operator developed in our group. The method is called CASCCSD. The energy and amplitude equations for the method and the corresponding computer code have been generated using a computerized automative procedure that in the present work was extended to produce a parallel computer code. The complete CASCCSD wave function for N2 includes some selected eight-fold excitations in the CC operator. An analysis of the wave function estimates the importance of those excitations at large internuclear separations.
An analytic treatment of percolation in simple fluids

The percolation behavior of simple fluids, modeled by a pair potential with a hard core and Yukawa tail, is studied by solving the connectedness Ornstein–Zernike equation analytically in the mean‐spherical approximation for two different connectedness models. The simplest connectedness model is defined by a ‘‘connectedness shell’’ concentric to the sphere that defines the hard core. The analytical solution applies to the case of the shell width less than the hard‐core diameter, which is the case for most applications of physical interest. The percolation loci on the phase diagram have been determined along with the average coordination number, which is found to be essentially constant along each locus, but different for different loci. A second model is introduced in which direct connectedness‐in‐probability is defined and applied to the gelation problem. This model can be thought of as a continuum generalization of the lattice model of gelation introduced by Coniglio, Stanley, and Klein. In the mean‐sphe.
A study of turbulent partially premixed flames based on simultaneous imaging of velocity field and oh radical

Turbulent partially premixed methane flames stabilized in a concentric flow conical nozzle burner have been investigated and presented in this work. The flames are classified in the thin reaction zones regime. The flames were investigated experimentally based on simultaneous measurements of the velocity field and OH-radical. A combined planar imaging velocimetry (PlV) and laser-induced predissociation fluorescence (LIPF) technique was applied. The mean, rms, and instantaneous structure of four flames are presented and discussed in this article. High stability of the investigated flames is partially due to the partial premixing of the jet and mainly to the flow divergence created by the conical nozzle. This creates a stabilization core with lower mean velocity at the center and lower rms of the velocity fluctuations at the flame brush. No significant recirculation could be observed within the stabilization core above the conical nozzle tip. The reaction zone structure in the present partially premixed flames is likely to show double reaction zones in all flames that support earlier theory and experiments.
Insight from Economically Optimal Steady-State Operating Policies for Dynamic Plantwide Control

Shortcut methods for the rapid determination of the optimal steady-state operating policy for certain classes of chemical plants have recently been published [Ward et al., Ind. Eng. Chem. Res. 2004, 43, 3957; 2005, 44, 6729]. The purpose of this work is to investigate the implications of these optimal operating policies for the selection of control methodology and control structure design, and to demonstrate that the operating policies can be implemented dynamically. These methods can predict, using basic information about the process chemistry, whether a self-optimizing control structure will give good economic performance, or whether an explicit optimization layer will be required in the control hierarchy. When a self-optimizing control structure is sufficient, this methodology allows the engineer to anticipate which binary pairings between controlled and manipulated variables are optimal. When an optimizing control layer (e.g., MPC or real-time optimizer (RTO)) is required, the method suggests a low-or.
Identification of potential core genes in hepatoblastoma via bioinformatics analysis

Hepatoblastoma is the childhood liver cancer. Profound efforts have been made to illuminate the pathology, but the molecular mechanisms of hepatoblastoma are still not well understood. To identify the candidate genes in the carcinogenesis and progression of hepatoblastoma, microarray dataset GSE131329 was downloaded from Gene Expression Omnibus (GEO) database. The differentially expressed genes (DEGs) were identified, and pathway and Gene Ontology (GO) enrichment analysis were performed. The protein-protein interaction network (PPI), module analysis, target gene - miRNA regulatory network and target gene - TF regulatory network were constructed and analyzed. A total of 996 DEGs were identified, consisting of 499 up regulated genes and 497 down regulated genes. The pathway and Gene Ontology (GO) enrichment analysis of the DEGs include proline biosynthesis, superpathway of tryptophan utilization, chromosome organization and organic acid metabolic process. Twenty-four hub genes were identified and biological process analysis revealed that these genes were mainly enriched in cell cycle, chromosome organization, lipid metabolic process and oxidation-reduction process. Validation of hub genes showed that TP53, PLK1, AURKA, CDK1, ANLN, ESR1, FGB, ACAT1, GOT1 and ALAS1 may be involved in the carcinogenesis, invasion or recurrence of hepatoblastoma. In conclusion, DEGs and hub genes identified in the present study help us understand the molecular mechanisms underlying the carcinogenesis and progression of hepatoblastoma, and provide candidate targets for diagnosis and treatment of hepatoblastoma.
Frequency Dependence of Orientation in Dynamically Sheared Diblock Copolymers

The frequency dependence of the dynamic shear viscosity together with the results of large amplitude oscillatory shear on a lamellar styrene/isoprene diblock copolymer indicate three frequency regimes in which different mechanisma are suggested to dominate the orientational behavior of the phase-separated lamellar structure. In the high frequency regime viscoelastic contrast between the PS and PI blocks is predominant. At intermediate frequencies lamellar interface destruction and reorganization occurs. At low frequencies the interface reorients as a whole
Determination of Phenylethanoid Glycosides in Lagotis brevituba Maxim. by High-Performance Liquid Chromatography–Electrospray Ionization Tandem Mass Spectrometry

High performance liquid chromatography coupled with electrospray ionization quadrupole-time-of-flight tandem mass spectrometry was used to profile the phenylethanoid glycosides in Lagotis brevituba. A total of twenty-three phenylethanoid glycosides were characterized by comparing the retention time and fragmentation with standards, accurate mass measurements, and fragmentation at low and high collision energies. Most phenylethanoid glycosides were reported in L. brevituba for the first time. This established method may be employed for comprehensive quality control of L. brevituba.