Miracle-dz/UniFAR-FTUs huggingface dataset:
University of Groningen The relative value of operon predictions

For most organisms, computational operon predictions are the only source of genome-wide operon information. Operon prediction methods described in literature are based on (a combination of) the following five criteria: (i) intergenic distance, (ii) conserved gene clusters, (iii) functional relation, (iv) sequence elements and (v) experimental evidence. The performance estimates of operon predictions reported in literature cannot directly be compared due to differences in methods and data used in these studies. Here, we survey the current status of operon prediction methods. Based on a comparison of the performance of operon predictions on Escherichia coli and Bacillus subtilis we conclude that there is still room for improvement.We expect that existing and newly generated genomics and transcriptomics data will further improve accuracy of operon prediction methods.
Interactive Production Performance Feedback in the IDE

Because of differences between development and production environments, many software performance problems are detected only after software enters production. We present PerformanceHat, a new system that uses profiling information from production executions to develop a global performance model suitable for integration into interactive development environments. PerformanceHat's ability to incrementally update this global model as the software is changed in the development environment enables it to deliver near real-time predictions of performance consequences reflecting the impact on the production environment. We implement PerformanceHat as an Eclipse plugin and evaluate it in a controlled experiment with 20 professional software developers implementing several software maintenance tasks using our approach and a representative baseline (Kibana). Our results indicate that developers using PerformanceHat were significantly faster in (1) detecting the performance problem, and (2) finding the root-cause of the problem. These results provide encouraging evidence that our approach helps developers detect, prevent, and debug production performance problems during development before the problem manifests in production.
Diagnosis of parametric faults in multivariable nonlinear systems

This paper presents a new fault diagnosis scheme for parametric faults in nonlinear multivariable systems. It uses two consecutive observers, one for the state reconstruction and the second one as a reference model for the residual generation. Hence, the first one has to be robust against faults whereas the second one is sensitive to them. Faults are detected by calculating the moving norm of the difference between system output and reference model output. For fault isolation, this difference is compared to fault functions that are generated for given sets of faults. For this purpose, the moving angle serves as a measure of similarity. Moreover, small model uncertainties are considered. The theoretical results are confirmed by an simulation example.
A MULTI-AGENT ARCHITECTURE FOR EVACUATING PILGRIMS IN PANIC AND EMERGENCY SITUATIONS : THE HAJJ SCENARIO

This paper proposes and presents the details of an agent-based architecture that has the capacity to model, simulate the movement of, and guide crowds with panic behavior in highly-dense areas in the events of manmade and natural threats. The most populated human gathering in the world, the Muslim pilgrimage event (also known as Hajj) which attracts more than two million people in six days is chosen to guide the identification of the requirements and main concepts of the agent simulation. The inferred requirements are used to guide the selection of an appropriate simulation tool following an extensive survey of potential simulation tools. The architecture uses software agents to represent groups of people along with their real time characteristics such as density, movements and panic levels, collected from various data sources. Support vector machine is combined with the fuzzy logic theory to predict pilgrims' behaviors and movements in case of panic situations. Initial simulation tests and results of the SVM model demonstrated that it is feasible to minimise the problem of modelling large crowds by selecting the best representative crowds that best reflect pilgrims’ behaviors. Furthermore, the implications of this architecture and a future
Blended IMS messaging applications

The attractiveness of the IP Multimedia Subsystem (IMS) is the flexibility that this new infrastructure brings to the deployment of new and novel multimedia applications. To date, IMS has been used for live, session-oriented communications. This paper observes that the basic principles organizing the IMS extend naturally to other important application architectures and that the use of the common IMS enablers between conversational sessions and store-and-forward messaging will spawn a new generation of blended services.
[Plasmodium prevalence and parasitic burden in blood donors of Brazzaville, Congo].

To assess the frequency of malaria-infected blood donations in Brazzaville (Congo) thick films from all blood donors (n = 12,375, minimum per month: 857, maximum per month: 1,295; sex ratio: 9.6) at the Brazzaville University Hospital were examined quantitatively for Plasmodium (screening threshold: 20/microliters of blood) over one year (1989). The overall prevalence rate for all species of Plasmodium was 8.5%. It varied according with age but not with sex. P. falciparum predominated (92%), followed by P. malariae (7%) and P. ovale (3%). For P. falciparum: 1--the prevalence rate was 7.8% but varied over the year from 4.8% in August (6.2% for the dry season on the whole) to 11.5% in March (9.6% for the rainy season); 2--the parasitic load, also variable according to the season, was over 600/microliters in 24% of the cases (i.e. 1.9% of all donations) and over 6,000/microliters in 15 cases (i.e. 1.6% of the cases). In conclusion the proportion of blood donations infected with P. falciparum (with a parasitic load > or = 20/microliters) varied in Brazzaville from 6% in the dry season to 10% in the rainy season.
Towards a Cognizant Virtual Software Modeling Assistant using Model Clones

We present our new ideas on taking the first steps towards cultivating synergy between model-driven engineering (MDE), machine learning, and software clones. Specifically, we describe our vision in realizing a cognizant virtual software modeling assistant that uses the latter two to improve software design and MDE. Software engineering has benefited greatly from knowledge-based cognizant source code completion and assistance, but MDE has few and limited analogous capabilities. We outline our research directions by describing our vision for a prototype assistant that provides suggestions to modelers performing model creation or extension in the form of 1) complete models for insertion or guidance, and 2) granular single-step operations. These suggestions are derived by detecting clones of the in-progress model and existing domain, organizational, and exemplar models. We overview our envisioned workflow between modeler and assistant, and, using Simulink as an example, illustrate different manifestations including multiple overlays with percentages and employing variant elements.
Oral Health Status of Asthmatic Children: A Review

Asthma is a chronic inflammatory condition that causes the airways to constrict , making breathing difficult. It is characterized by the obstruction of airflow which is variable over a short period of time. This condition is reversible, either spontaneously or can be controlled with the help of drugs. Asthma medication comprises bronchodilators, corticosteroids and anticholinergic drugs. Most of these drugs are inhaled using various forms of inhalers or nebulizers. The effect of these drugs on oral health is the subject of debate among dental practitioners. Patients taking asthma medication may be at risk of dental caries, dental erosion, periodontal diseases and oral candidiasis. Hence, patients with bronchial asthma on medication should receive special prophylactic attention. This article reviews the oral health status of asthmatic children, and suggests various measures to counter possible oral health problems related to asthma.
COMPARISON OF COMPLETE BOUGUER ANOMALIES FROM SATELLITE MARINE GRAVITY MODELS WITH SHIPBORNE GRAVITY DATA IN EAST SEA, KOREA

This paper describes the results of complete bouguer anomalies (B.A) computed from the free-air anomalies (F.A) of Sandwell and DTU13 marine gravity models that derived from satellite altimetry observations in the area of East Sea, South Korea. In order to confirm the usefulness of satellite-derived gravity anomalies to analyze the geophysical, geological and geographical characteristics in East Sea, the results of marine gravity models have been compared with shipborne gravity anomalies obtained from KHOA (Korea Hydrographic and Oceanographic Agency). To calculate the complete B.A, we applied complete bouguer correction which consists of three steps: the bouguer slab correction (Bullard A), the curvature correction (Bullard B) and the terrain correction (Bullard C). All these corrections have been computed over the East Sea with the 1'  1' bathymetric data derived from ETOPO1 global relief model. In addition, a constant topographic and sea-water density, 2,670 kg/m and 1,030 kg/m, has been used for all correction terms according to the location of gravity points respectively. The distribution of complete B.A computed from Sandwell and DTU13 are very similar to each other with similar statistics i.e., mean of around 101.9  42 mGal. But, the differences with the complete B.A. calculated from shipborne gravities are slightly different over the whole study area, especially around Dok-do and Ulleung-do island, and also in the south-eastern part of Ulleung basin. As the final result, both models shows similar difference and variation, but Sandwell model shows little closer precision towards the shipborne observation data than DTU13 model in the study area. Hence, Sandwell model with the proper complete bouguer correction can be used as an alternative in effective application of gravity data to analyze the geophysical, geological and geographical characteristics in those areas which are not covered by shipborne gravity observations in large area of East Sea. But both combined or separately can also be used in case island or abyssal hill structures with higher slope can be avoided.
On Recommended System Using Collaborative Filtering Method With Apache

Apache mahout is currently developing a recommendation system that uses the Collaborative Filtering method, but in its implementation still lacks in processing time that still takes a long time to process large data. This research will utilize multithreading to speed up data processing time on apache mahout. In this research, it is known that the existence of multithreading able to increase its performance in processing data execution time on apache mahout. From the test that has been done with the amount of 20 million data, obtained the test results on the singlethread with the duration of data processing for 2218 seconds. And on the test for 4 threads obtained 764 seconds, and then for 8 threads obtained 691 seconds results and on the test for 16 threads obtained results 1097 seconds. From how many tests have been done has proven that multithreading able to improve apache mahout performance in the recommendation system as long as the number of threads does not exceed the capacity of thread size in the processor. Keywords—Apache Mahout, Collaborative Filtering, Multithreading Techno.COM, Vol. 17, No. 1, Februari 2018 : 1-11
Tele-Mum: A Feasibility Study for a Randomized Controlled Trial Exploring the Potential for Telemedicine in the Diabetes Care of Those with Gestational Diabetes.

BACKGROUND The incidence of gestational diabetes mellitus (GDM)--hyperglycemia with onset or first recognition during pregnancy--is increasing and will have a significant impact on diabetes services. This study aimed to determine the feasibility and acceptability of using telemedicine in the diabetes care of women with GDM and the possibility of replacing alternate (one in every two) diabetes review appointments with telemedicine. SUBJECTS AND METHODS A feasibility study for a randomized controlled trial was conducted across two sites. Fifty women with GDM were randomized to usual care (n = 26) or usual care plus telemedicine (n = 24). Telemedicine entailed weekly blood pressure and weight measurements and transmission of these data, along with blood glucose readings, for review by the healthcare team. Patients were contacted about these results as necessary. Patients completed questionnaires to measure their satisfaction with telemedicine or blood glucose monitoring. The intervention group and healthcare providers also took part in qualitative interviews. Analysis involved descriptive statistics for the satisfaction questionnaires and framework analysis for the qualitative interviews. RESULTS Eighty-nine percent of patients were satisfied with telemedicine and would use it again. Both HCPs and patients found the equipment easy to use and were positive about using it to replace alternate diabetes review appointments in the future. If used in this way, healthcare providers felt that protected time in which to perform the telemedicine review would be necessary. CONCLUSIONS Telemedicine may help meet the growing demand on diabetes services due to increasing numbers of women being diagnosed with GDM.
S ep 2 01 7 Oblivious transfer based on single-qubit rotations

We present a bit-string quantum oblivious transfer protocol based on single-qubit rotations. Our protocol is built upon a previously proposed quantum public-key protocol and its practical security relies on the laws of Quantum Mechanics. Practical security is reflected in the fact that, due to technological limitations, the receiver (Bob) of the transferred bit-string is restricted to performing only “few-qubit” coherent measurements. We also present a single-bit oblivious transfer based on the proposed bit-string protocol. The protocol can be implemented with current technology based on optics. ∗email: ansouto@fc.ul. pt
Fetal Death in a Patient With Intrahepatic Cholestasis of Pregnancy

BACKGROUND: Treatment with ursodeoxycholic acid in intrahepatic cholestasis of pregnancy reduces concentration of transaminases and bile acids in maternal serum, and is thought to reduce fetal death. We report a case of fetal death in a patient with intrahepatic cholestasis of pregnancy who had responded well to ursodeoxycholic acid, demonstrated by a low bile level. CASE: A young nulliparous woman presented with intrahepatic cholestasis of pregnancy at 28 weeks of gestation. Transaminases and bile acids decreased after ursodeoxycholic acid administration. The patient was discharged from the hospital until delivery and received biochemical markers and conventional fetal monitoring twice weekly. Due to low bile acid values (< 13 UI/L) and unfavorable cervix, the patient was followed up expectantly. Fetal death occurred at 39 weeks and 3 days, although cardiotocograph testing results were normal the day before. CONCLUSION: When lung maturity is achieved for patients with intrahepatic cholestasis of pregnancy, delivery should be considered.
Sugar-Inducible Expression of a Gene for [beta]-Amylase in Arabidopsis thaliana

The levels of [beta]-amylase activity and of the mRNA for [beta]-amylase in rosette leaves of Arabidopsis thaliana (L.) Heynh. increased significantly, with the concomitant accumulation of starch, when whole plants or excised mature leaves were supplied with sucrose. A supply of glucose or fructose, but not of mannitol or sorbitol, to plants also induced the expression of the gene for [beta]-amylase, and the induction occurred not only in rosette leaves but also in roots, stems, and bracts. These results suggest that the gene for [beta]-amylase of Arabidopsis is subject to regulation by a carbohydrate metabolic signal, and expression of the gene in various tissues may be regulated by the carbon partitioning and sink-source interactions in the whole plant. The sugar-inducible expression of the gene in Arabidopsis was severely repressed in the absence of light. The sugar-inducible expression in the light was not inhibited by 3(3,4-dichlorophenyl)-1,1-dimethylurea or by chloramphenicol, but it was inhibited by cycloheximide. These results suggest that a light-induced signal and de novo synthesis of proteins in the cytoplasm are involved in the regulation. A fusion gene composed of the 5[prime] up-stream region of the gene for [beta]-amylase from Arabidopsis and the coding sequence of [beta]-glucuronidase showed the sugar-inducible expression in a light-dependent manner in rosette leaves of transgenic Arabidopsis.
Vitamin and Mineral Composition of Preterm Human Milk : Implications for the Nutritional Management of the Preterm Infant

Optimal nutritional management of preterm (PT) infants, particularly those less than 1,500 g birthweight, is believed to be critical to their growth, survival, and ultimate well-being; however, specific nutritional goals in the management of such high-risk neonates are not well defined. The American Academy of Pediatrics (1) suggests that the most logical approach at present is to achieve a postnatal growth that approximates the growth in utero of a normal fetus of the same postconceptional age. Ideally, this growth should begin by the second week of life, i.e., after changes in body water distribution have occurred and adjustments to enteral feeds and/or parenteral supplements have taken place (1). Some of the frequently cited advantages of human milk in infant feeding are bioavailability of nutrients, absence of foreign proteins, and presence of anti-infective properties; these would appear particularly beneficial to PT infants, since they exhibit greater limitations than term infants in gastrointestinal and digestive functions, as well as in immunological status (2). Despite the potential benefits of human milk, its nutritional adequacy for PT infants has been questioned by findings indicating that banked mature human milk collected from mothers who delivered at termfailed to provide adequate nutrients to support the theoretical intrauterine growth rates of PT infants (3-6). The nutritional adequacy of term milk produced during the early weeks postpartum to meet the needs of PT infants remains to be tested. Unlike the findings with pooled mature human milk or formula, PT infants fed their own mother's milk showed a more rapid rate of growth with respect to length and head circumference, and were able to gain weight more rapidly (6). Several reviews (1,7-10) have updated our knowledge with regard to the nutritional management of PT infants, including the use of PT milk.
Preliminary study on the interrelation between sow milk quality and litter performance in relation to their health.

Our objective was to determine whether the increase through diet of the fatty acids (FA) composition in sows colostrum and milk was associated with litter performances and their biochemical profile. The study was conducted in 4 sows TOPIGS (48 litter) allocated into 2 groups: control and Hemp diets. Litters were divided into two dietary treatments: control diet and control plus 2.5% additive based on L acidophilus (50%) and L. Plantarum (50%) bacterial strain. The FAs composition of the colostrum and milk (7 and 21 days) was determined by gas chromatography. The sow and litter biochemical profile was determined with BS-130 automatic analyser. The addition of hemp in feed of Hemp group sows starting the last 10 days of gestation significantly influenced the colostrum and milk composition in polyunsaturated FAs, n-3 and n-6 FAs. In Hemp group αlinolenic FA content in colostrum was 1.4 times higher than in the control group, 1.64 times higher after 7 days of lactation and 1.45times higher after 21 days of lactation compared to control group. The dietary addition of hemp lead to a reduction of ratio n-6: n-3 in milk. This was positive reflected in the litter performances (>3.8% at litter from Hemp group sow compared to C group) and their health. The microbial additive reinforced the positive effects on growth parameters (>20%at litter from Hemp group sow and > 25% at litter from control group respectively). Both sows and piglets serum biochemical parameters were within physiological limit. In conclusion, feed composition can beneficially influence colostrum / milk fatty acids composition in relation to litter performances, biochemical parameters and health. Milk fat quality had positive effects on piglet performance and their health, as shown by the biochemical plasma parameters.
Building Mathematical Power: Why Change is So Difficult

The purpose of this paper is to report the lessons gleaned from a year-long staff development teacher training experience with urban teachers. The paper addresses the current research on teacher development, describes the implementation of best practices, and shares the results of the year-long study. Very little has been written on the role and the accountability of the facilitators who are hired to provide staff development. These staff developers recognized the need to address their own practices before questioning the impact on teacher development. The study found that teacher growth has much to do with who facilitates the experience, how responsible they feel, and what they do to foster deeper relationships with the faculty and the organization.
Individual psychological singularities of persons with disabling diseases

This article deals with the study of individual psychological features of men and women in the difficult circumstances of disability. The individual psychological characteristics are understood as the parameters of the meaningfulness of life, pseudocompensations, and personal properties. This study has managed to detect the gender dependence of the studied parameters’ relationships. The observed specificity of the relationships’ structural organization is the criterion of adaptation to the difficult circumstances. The differences between men and women were identified in quantitative values, which are the markers of adaptation of disabled persons to difficult circumstances. These features must be taken into account by the service of medical and social examination, by rehabilitation specialists at developing individual rehabilitation programs for disabled people.
The place of upper dorsal sympathectomy in the treatment of primary raynaud's disease

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