Miracle-dz/UniFAR-FTUs huggingface dataset:
État de surface implantaire et péri-implantite chez les patients avec un antécédent de maladie parodontale : analyse de la littérature

Contexte : Depuis le debut du 21e siecle, les fabricants ont developpe de nombreuses techniques de traitement rendant les surfaces plus rugueuses, visant a ameliorer l’osteointegration primaire. Mais si le taux d’echec implantaire precoce semble avoir diminue, le taux de pathologie peri-implantaire reste alarmant. Il nous a donc semble interessant d’apporter des elements de reponse quant au choix de l’etat de surface implantaire, chez une partie non negligeable des patients rencontres de nos jours, a savoir les patients ayant eu un antecedent de parodontite. Materiels et methodes : Une analyse de la litterature a ete realisee sur les bases de donnees PubMed, concernant les 3 problematiques suivantes : - Antecedent de maladie parodontale et peri-implantite - Etat de surface et peri-implantite - Etat de surface et peri-implantite chez les patients ayant eu un antecedent de maladie parodontale. Resultats : Les patients ayant eu un antecedent de parodontite chronique ou agressive semblent avoir un risque plus eleve de delopper une peri-implantite surtout si celle ci est non traitee et stabilisee. Les surfaces poreuses favorisent fortement l’apparition de peri-implantite, les surfaces moderement rugueuses semblent induire une apparition plus precoce que les surfaces usinees, surtout chez les patients ayant eu un antecedent de maladie parodontale. Conclusion : Chez les patients ayant un antecedent de maladie parodontale, il semble judicieux d’appliquer le principe de precaution en utilisant des implants a surfaces usinees, si la qualite de l’os le permet, afin d’eviter la survenue de maladie peri-implantaire. Des etudes prospectives et comparatives plus poussees sont neanmoins necessaires pour conclure definitivement.
Protein sulfhydryls and their role in the antioxidant function of protein S-thiolation.

Protein S-thiolation/dethiolation, i.e., the oxidation of protein sulfhydryls to mixed disulfides and their reduction back to sulfhydryls, is an early cellular response to oxidative stress (1-5). This response may be elicited by oxidative phenomena of diverse origins, and the few cases that have been studied extensively give a limited insight into the metabolic roles and the molecular mechanism of the process. Much of our current understanding arose from experiences with isolated proteins containing "reactive" sulfhydryls (6, 7), but recent experiments at the cellular level have begun to reveal interesting insights that suggest a complexity and importance not appreciated previously (8). This article will discuss the current status of experiments that relate to both the role of the cellular process and to the reactivity of selected proteins that participate in the cellular processes. The discussion will center on the role of glutathione, a molecule of central interest in every aspect of protein S-thiolation and dethiolation.
An Empirical Investigation of Cloud Computing for Personal Use

Cloud computing is rapidly diffusing among individuals for personal use. By reviewing extant literature on individual adoption and use of information technology, this research develops a theoretical model to explicate the use of cloud computing for personal use. The proposed research model is empirically evaluated using a nationally drawn sample of 960 individuals. Partial Least Squares, a variance-based structural equation modeling technique, is used to analyze the research model. We discuss the results and identify areas for future research.
Inversion of the X‐ray transform from limited angle parallel beam region of interest data with applications to electron tomography

We present a new local tomographic algorithm applicable to electron microscopy tomography. Our algorithm applies to the standard data acquisition method, single‐axis tilting, as well as for more arbitrary acquisition methods. Using microlocal analysis we put the reconstructions in a mathematical context, explaining which singularities are stably visible from the limited data given by the data collection protocol in the electron microscope. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Effects of three different training modalities on the cross sectional area of the lumbar multifidus muscle in patients with chronic low back pain

Objectives—To determine the effect of different training schedules on the cross sectional area (CSA) of the lumbar multifidus muscle in patients with chronic low back pain. Methods—Each of 59 nine patients was randomly assigned to one of three programmes: 10 weeks of stabilisation training (group 1; n = 19); 10 weeks of stabilisation training combined with dynamic resistance training (group 2; n = 20); 10 weeks of stabilisation training combined with dynamic-static resistance training (group 3; n = 20). Before and after 10 weeks of training, multifidus CSAs were measured from standard computed tomography images at three different levels (upper end plate of L3 and L4, and lower end plate of L4). Results—The CSA of the multifidus muscle was significantly increased at all levels after training in group 3. In contrast, no significant differences were found in groups 1 and 2. Conclusions—General stabilisation exercises and dynamic intensive lumbar resistance training have no significant effect on the CSA of the lumbar multifidus muscle in patients with chronic low back pain. The static holding component between the concentric and eccentric phase was found to be critical in inducing muscle hypertrophy during the first 10 weeks. Treatment consisting of stabilisation training combined with an intensive lumbar dynamic-static strengthening programme seems to be the most appropriate method of restoring the size of the multifidus muscle.
Methodologic issues in collecting data from debilitated patients with cancer near the end of life.

PURPOSE/OBJECTIVES To report the experience of a group of researchers who have had a year of experience in a clinical trial with homecare hospice patients. SAMPLE 150 hospice patients with cancer and their primary caregivers who were accrued to a National Cancer Institute-funded clinical trial focusing on quality of life. METHODS The investigative team kept careful records of the numbers of patient/caregiver dyads accrued to the study and the reasons for nonaccrual as well as reasons for attrition. Data were analyzed using descriptive statistics. FINDINGS During a nine-month period, the hospice admitted 2,517 patients; 75% had cancer and 95% had caregivers, making them eligible for the study. However, after further screening, only 19% were eligible for contact and only 5% finally were accrued to the study. For the 125 patient/caregiver dyads actually accrued to the study, baseline data were obtained on only 50% and evaluable follow-up data on only 50%. CONCLUSIONS Accruing patients to clinical trials and retaining them when they are critically ill and near death are extraordinarily difficult tasks. The inability to recruit and retain subjects for clinical trials has implications for integrity of data, data analysis, success of the project, and the cost of conducting such projects in the future.
Effects of housing conditions and season on the activity rhythm of spider monkeys (Ateles geoffroyi) kept under natural conditions within their distributional range in Central Mexico

The timing and pattern of mammalian behavioral activities are regulated by an evolutionary optimized interplay of the genetically based biological (circadian) clock located in the brain’s suprachiasmatic nuclei and direct responses to environmental factors that superimpose and thus mask the clock-mediated effects, the most important of which is the photically induced phase-setting (synchronization) of the circadian rhythmicity to the 24-hour solar day. In wild and captive animals living under the natural conditions prevailing in their habitat, to date, only a few attempts have been made to analyze the role of these two regulatory mechanisms in the species’ adaptation to the time structure prevailing in their habitat. We studied the impact of housing conditions and season on the daily timing and pattern of activity in Mexican spider monkeys (Ateles geoffroyi). To this end, we carried out long-term activity recordings with Actiwatch® AW4 accelerometer/data-logger devices in 11 adult Ateles living under identical natural lighting and climatic conditions in either a large wire netting cage or a 0.25 ha forest enclosure in the primatological field station of Veracruz State University near Catemaco, Mexico. In a gravid female in the forest enclosure, we obtained first-hand information on the effect of late pregnancy and parturition on the monkey’s activity rhythm. The Ateles behaved strictly diurnal and undertook about 90% of daily total activity during this activity time. Due to a higher second activity peak in late afternoon, the bimodal activity pattern was more pronounced in monkeys living in the forest enclosure. Although the spider monkeys kept there had an earlier activity onset and morning activity peak than their conspecifics in the cage, no consistent differences were found in the parameters characterizing the phase-setting of the circadian system to the environmental 24-h periodicity, either by comparison or correlation with the external time markers of sunrise (SR) and sunset (SS). The most obvious effect of late pregnancy, parturition and lactation was a distinct reduction of the activity level during the week of parturition and the next. Seasonal variations in the form of significant differences between the long-day summer half year and the short-day winter half year were established in the phase-angle differences of the morning activity peak to SR, in the evening activity peak and activity offset to SS, as well as in the activity time and the peak-to-peak interval, but not in the phase position of activity onset to SR or in the height of the morning and evening activity peak. These findings in combination with a high variability of the phase angle differences indicate that in A. geoffroyi, a relatively weak circadian component and strong masking direct effects of environmental factors are involved in the regulation of the daily activity rhythm.
Extraction and identification of trophoblast cells circulating in peripheral blood during pregnancy

Summary. Trophoblast cells circulating in peripheral venous blood during pregnancy were extracted by differential centrifugation and identified by indirect immunofluorescence with antitrophoblast microvillus antibody. In a study where trophoblast identification was checked by blind comparison with non‐pregnant control subjects’ trophoblast cells were detected in six out of 10 pregnant women studied.
Lactational response of dairy cows to diets varying in ruminal solubilities of carbohydrate and crude protein.

Sixty high producing Holstein cows were randomly assigned in a 3 x 2 factorial to evaluate three sources of carbohydrates that differed in solubility and degradability (corn, barley, and dried whey) with two sources of CP solubility (soybean meal and urea) during wk 4 through 14 postpartum. Total mixed diets, formulated to be isonitrogenous at 16% CP, contained (DM basis) 40% corn silage, 10% chopped alfalfa hay, and 50% of the respective concentrate mix. Milk production (32.8, 31.5, and 31.3 kg/d) was highest for cows fed corn, whereas 4% FCM (30.0, 27.9, and 29.5 kg/d) was similar for cows fed corn and dried whey and lower for cows fed barley. Percentages of fat (3.37, 3.36, and 3.51) and protein (3.05, 3.00, and 2.98) were similar for cows fed all carbohydrate sources. Solubility of protein (soybean meal versus urea) did not affect production of milk (32.2 and 31.5 kg/d) and 4% FCM (29.4, and 28.9 kg/d). Intake of DM was lowest for cows fed barley (20.4, 18.8, and 20.5 kg/d), and intakes were similar (19.9 and 19.9 kg/d) for cows fed soybean meal and urea. Providing sources of carbohydrates in the diet that are more soluble and degradable (i.e., barley or dried whey) did not give the expected increase in utilization of a highly soluble CP source (urea) for milk production.
Características y resultados de las eventrorrafias del grupo de pared abdominal de un hospital universitario. Bogotá, Colombia

Antecedentes. Las eventraciones son el segundo tipo de hernias mas comunes. Cada ano se realizan mas de 150.000 eventrorrafias en los Estados Unidos generando costos directos a los sistemas de salud y complicaciones en los pacientes. Objetivo. Describir las caracteristicas y desenlaces de los pacientes sometidos a reparacion de eventraciones entre el 1 de enero del 2013 y el 31 de diciembre del 2017 en el Hospital Universitario Mayor - Mederi. Diseno y metodos. Se realizo un estudio observacional, descriptivo, con informacion recolectada de forma retrospectiva. Se incluiran pacientes sometidos a cirugia de reparacion de la hernia incisional (eventracional) en el Hospital Universitario Mayor - Mederi. Se aplicaron metodos de analisis descriptivo y analitico con el fin de describir y explorar relaciones entre variables. Resultados. Se incluyeron 562 pacientes. Las eventraciones mayores a 10 cm ocurrieron en el 28,5% de los casos. En personas con eventraciones mayores a 10 cm se encuentro relacion con el antecedente de eventraciones, eventrorrafia y manipulacion del tracto gastrointestinal. Las hernias de ubicacion epigastrica (21,2%), umbilical (26,2%) e infraumbilical (17,6%) fueron las mas frecuentes. El antecedente de eventracion, eventrorrafia, hernia mayor a 10 cm y manipulacion del tracto gastrointestinal mostraron relacion con el desarrollo de las hernias en estas ubicaciones. La posicion de la malla que se empleo con mayor frecuencia fue la ONLAY (76,8%). La recidiva ocurrio en el 2,7% de los pacientes. Los seromas aparecieron como complicacion en el 9% de los pacientes. Conclusion. La recidiva ocurre con cierta frecuencia en los pacientes operados por reparacion de hernia incisional. Los seromas, el tamano de la hernia, antecedente de eventrorrafia y eventracion estan relacionados con el desarrollo de la hernia incisional y sus desenlaces.
A Machine Learning Approach to Quantitative Prosopography

Prosopography is an investigation of the common characteristics of a group of people in history, by a collective study of their lives. It involves a study of biographies to solve historical problems. If such biographies are unavailable, surviving documents and secondary biographical data are used. Quantitative prosopography involves analysis of information from a wide variety of sources about "ordinary people". In this paper, we present a machine learning framework for automatically designing a people gazetteer which forms the basis of quantitative prosopographical research. The gazetteer is learnt from the noisy text of newspapers using a Named Entity Recognizer (NER). It is capable of identifying influential people from it by making use of a custom designed Influential Person Index (IPI). Our corpus comprises of 14020 articles from a local newspaper, "The Sun", published from New York in 1896. Some influential people identified by our algorithm include Captain Donald Hankey (an English soldier), Dame Nellie Melba (an Australian operatic soprano), Hugh Allan (a Canadian shipping magnate) and Sir Hugh John McDonald (the first Prime Minister of Canada).
Potential Influence of Advance Care Planning and Palliative Care Consultation on ICU Costs for Patients With Chronic and Serious Illness*

Objectives:To estimate the potential ICU-related cost savings if in-hospital advance care planning and ICU-based palliative care consultation became standard of care for patients with chronic and serious illness. Design and Setting:Decision analysis using literature estimates and inpatient administrative data from Premier. Patients:Patients with chronic, life-limiting illness admitted to a hospital within the Premier network. Interventions:None. Measurements and Main Results:Using Premier data (2008–2012), ICU resource utilization and costs were tracked over a 1-year time horizon for 2,097,563 patients with chronic life-limiting illness. Using a Markov microsimulation model, we explored the potential cost savings from the hospital system perspective under a variety of scenarios by varying the interventions’ efficacies and availabilities. Of 2,097,563 patients, 657,825 (31%) used the ICU during the 1-year time horizon; mean ICU spending per patient was 11.3k (SD, 17.6k). In the base-case analysis, if in-hospital advance care planning and ICU-based palliative care consultation were systematically provided, we estimated a mean reduction in ICU costs of 2.8k (SD, 14.5k) per patient and an ICU cost saving of 25%. Among the simulated patients who used the ICU, the receipt of both interventions could have resulted in ICU cost savings of 1.9 billion, representing a 6% reduction in total hospital costs for these patients. Conclusions:In-hospital advance care planning and palliative care consultation have the potential to result in significant cost savings. Studies are needed to confirm these findings, but our results provide guidance for hospitals and policymakers.
Hybrid photonic/plasmonic ZnO/Au composites for sensing applications

We have studied the enhancement factors (EF) in Surface Enhanced Raman Scattering (SERS) substrates prepared with self assembled ZnO nanorod arrays and Au nanocrystals. The ZnO/Au composite nanoarrays present experimental EF values as high as ∼07 for detection of Rhodamine 6G (R6G) using an excitation wavelength of 633 nm. We have study the EF via numerical simulations of a single ZnO/Au composite nanorod using a FDTD algorithm. Our results indicate that the coupling between the photonic wave guiding in the ZnO nanorod and the plasmonic resonance in the Au nanocrystals plays a significant role in the observed EF and need to be considered to fully understand and optimize the development of high efficiency, reproducible, and stable SERS substrates.
Genetic variants in the serotonin transporter influence the efficacy of bupropion and nortriptyline in smoking cessation.

AIMS We investigated whether variants in the serotonin transporter gene (SLC6A4) influence smoking cessation rates using antidepressant therapy (i.e. bupropion and nortriptyline). DESIGN Pharmacogenetic (secondary) analysis of a randomized, placebo-controlled efficacy trial of bupropion and nortriptyline for smoking cessation. SETTING Single-centre study, Maastricht University, the Netherlands. PARTICIPANTS A total of 214 of 255 (84%) current daily smokers participating in a randomized controlled efficacy trial. MEASUREMENTS Subjects were genotyped for three functional variants in SLC6A4 (5-HTTLPR, STin2, rs25531). Primary outcome measures were prolonged abstinence from weeks 4-12, 4-26 and 4-52. Secondary outcome measures included 7-day point prevalence abstinence at weeks 4, 12, 26 and 52. FINDINGS Carriers of the 5-HTTLPR high-activity L-variant had higher prolonged cessation rates with bupropion than placebo [odds ratio (OR) = 1.44, 95% confidence interval (CI) = 1.01-2.05, P = 0.04]. Combining the three variants resulted in increased prolonged cessation rates for both bupropion and nortriptyline among carriers of four to five high-activity variants (bupropion: OR = 2.00, 95% CI =1.21-3.29, P = 0.01; nortriptyline: OR = 1.91, 95% CI = 1.02-3.56, P = 0.04). Similar results were found for point prevalence abstinence. CONCLUSIONS Bupropion and nortriptyline seem to be more effective in smoking cessation among SLC6A4 high-activity variant carriers, probably by blocking the increased serotonin transporter activity, thereby increasing serotonin levels. Prospective studies have to assess if this can improve cessation rates when treatment is targeted at individuals based on their genotypes.
Biological Control of Yellow Starthistle (Centaurea solstitialis) in the Salmon River Canyon of Idaho

Abstract Yellow starthistle is an invasive, annual, spiny forb that, for the past 30 yr has been steadily advancing up the Salmon River Canyon in west central Idaho. In 1994, a decision was made to attempt to manage yellow starthistle by establishing a complex of biological control agents in a containment zone where the weed was most dense. Between 1995 and 1997, six species of seedhead-attacking insects were introduced and successfully established. By 1999, the insects had spread through the entire containment zone. Following this dispersal, a rapid buildup of insect populations occurred, and, since 2003, seed destruction has fluctuated around 90%. Vegetation monitoring plots, however, have shown no consistent decline in the overall population of yellow starthistle, indicating that the amount of seed produced is still sufficient to allow full replacement. However, county weed control personnel, who are responsible for surveying and destroying outlying populations of yellow starthistle beyond the containment zone, report that, during this period, the number of new, isolated pockets of yellow starthistle they are finding has dropped dramatically. This case study discusses how the biological control program partially met the objective of managing yellow starthistle by reducing the rate of advance of this weed in the Salmon River Canyon. Nomenclature: Yellow starthistle, Centaurea solstitialis L. CESO3
Tracking applications with fuzzy-based fusion rules

The objective of this paper is to present and evaluate the performance of a particular fusion rule based on fuzzy T-Conorm/T-Norm operators for two tracking applications: (1) Tracking Object's Type Changes, supporting the process of identification, (e.g. friendly aircraft against hostile ones, fighter against cargo) and consequently for improving the quality of generalized data association; (2) Alarms identification and prioritization in terms of degree of danger relating to a set of a priori defined, out of the ordinary dangerous directions. The aim is to present and demonstrate the ability of TCN rule to assure coherent and stable way for identification and to improve decision-making process in temporal way. A comparison with performance of DSmT based PCR5 fusion rule and Dempster's rule is also provided.