Miracle-dz/UniFAR-FTUs huggingface dataset:
Importance of mother tinctures and tissue remedies in the management of tumours

Tumour is ‘a mass of tissue formed as a result of abnormal, excessive, uncoordinated, autonomous and purposeless proliferation of cells even after cessation of stimulus for growth which caused it. ’[1] The fundamental abnormality resulting in the development of cancer is the continual unregulated proliferation of cancer cells. Rather than responding appropriately to the signals that control normal cell behaviour, cancer cells grow and divide in an uncontrolled manner, invading normal tissues and organs and eventually spreading throughout the body. Homoeopathy is among the most famous alternative system of medicine. Homeopathy recognizes the individuality of each patient. Homoeopathic mother tinctures and tissue remedies can help the patient very effectively and it can help these patients to improve their quality of life.
An Example of using Precision Medicine in CancerCare: Dynamic Change of TET2 Mutation in a Patientwith Therapy-related Myelodysplastic Syndrome/Acute Myeloid Leukemia

Background: Therapy-related Myelodysplastic Syndrome/Acute Myeloid Leukemia (t-MDS/AML) is a serious complication for cancer patients undergoing chemotherapy or radiation treatment. Determining the mechanisms behind disease progression will help to design targeted treatment strategies. The objective of this study was to investigate the genetic basis for t-MDS/AML development. Case: Exome sequencing analysis was performed for a t-MDS/AML patient to investigate the somatic mutation in coding genes at diagnosis, remission, allo-transplantation, and relapse. Results: The study observed dynamic changes of somatic mutation during disease development. A TGTG insertion mutation was indentified at exon 3 in Tet methylcytosine dioxygenase 2 (TET2) at diagnosis. This mutation caused a frameshift, generating a pre-matured stop codon downstream, and leading to loss-of-function of TET2. At post-allotransplantation and relapse, this mutation decreased to basal levels. Conclusions: The results suggest that the TET2-mutated clone might play more important roles in initiation than in relapse of t-MDS/AML, in which a new clone(s) with wild-type TET2 may became dominant.
The impact of long-term application of chemical fertilizers and straw returning on soil bacterial community

[Objective] The application of chemical fertilizers and straw returning are important agricultural strategies to improve the fertility of lime concretion black soil. However, there is little 2050 微生物学通报 Microbiol. China 2015, Vol.42, No.10 http://journals.im. ac.cn/wswxtbcn information about the impact of fertilization on microbial community in lime concretion black soil. The objective of this study was to investigate the effect of long-term application of chemical fertilizers and wheat straw returning on bacterial community in lime concretion black soil. [Methods] Quantitative PCR (qPCR) and 454 pyrosequencing-based analysis of the V4-V5 16S rRNA gene region were used to determine bacterial abundance, community structure and diversity in soils under different fertilization strategies. [Results] The most dominant bacterial phyla in lime concretion black soil were Actinobacteria, Proteobacteria, Acidobacteria, Chloroflexi and Bacteroidetes. Long-term application of chemical fertilizer greatly increased soil fertility, but resulted in significant bacterial community shift and diversity loss. Although wheat straw returning improved soil fertility, it could not mitigate the negative impact of chemical fertilizers on soil bacterial community. Statistical analysis revealed that changes in microbial community composition and diversity were strongly correlated with changes in pH induced by the fertilization regime. [Conclusion] Long-term application of chemical fertilizers and straw returning improved the fertility of lime concretion black soil, but soil acidification caused by fertilization had negative impact on soil bacterial community. Our results emphasized the importance of soil pH in addition to soil fertility for agricultural sustainability in lime concretion black soil region, and suggest that straw returning has little help for the stability of microbial community in lime concretion black soil, and comprehensive means must be taken to develop environmental friendly agriculture.
Principles of Quantum Communications and its Recent Advances

Quantum communication is becoming more and more practical based on recent research. This paper introduces simple quantum systems and the active/potential applications of quantum communication systems. Mathematics preliminaries and quantum information theory will be presented first. Then several simple applications of quantum systems in communication including quantum key distribution (QKD) will be mentioned. We can see that quantum information has completely different features compared to classical information. Th latest improvement based on satellite quantum channels allows us to expect a global quantum network. The inherent characteristic of quantum communication makes it theoretically immune to traditional eavesdropping.
Evolution of tissue-specific gene expression in mammals: How a new phosphoglycerate kinase gene was formed and refined

Darwin, biologists have learned to view the process of evolution in higher animals as the appearance of new characteristics that result in phenotypic modifications, which are then tested by natural selection and propagated if advantageous. As geneticists have defined the relationship between genes and phenotypic characteristics, the view of evolution has been refined to focus on the inheritance of specific genes or combinations of genes that are conserved because they confer an advantageous phenotype. However, by this view, the process of evolution is often assumed to be based solely on changes in the presence or structure of the individual proteins encoded by each gene-an overly simplistic perspective. Just as there is more to a symphony than the collection of individual notes that are played, the phenotype of a multicellular organism is the product not only of the individual genes that are expressed but also of the orchestration of that gene expression such that an appropriate temporal and spatial coordination is achieved. It is only through a comprehensive system of gene regulation that the development and differentiation of each individual cell lineage, and, subsequently, of a multicellular organism as a whole, can
SENCORPUS: A French-Wolof Parallel Corpus

In this paper, we report efforts towards the acquisition and construction of a bilingual parallel corpus between French and Wolof, a Niger-Congo language belonging to the Northern branch of the Atlantic group. The corpus is constructed as part of the SYSNET3LOc project. It currently contains about 70,000 French-Wolof parallel sentences drawn on various sources from different domains. The paper discusses the data collection procedure, conversion, and alignment of the corpus as well as it’s application as training data for neural machine translation. In fact, using this corpus, we were able to create word embedding models for Wolof with relatively good results. Currently, the corpus is being used to develop a neural machine translation model to translate French sentences into Wolof.
Glawinette: a Linguistically Motivated Derivational Description of French Acquired from GLAWI

Glawinette is a derivational lexicon of French that will be used to feed the Démonette database. It has been created from the GLAWI machine readable dictionary. We collected couples of words from the definitions and the morphological sections of the dictionary and then selected the ones that form regular formal analogies and that instantiate frequent enough formal patterns. The graph structure of the morphological families has then been used to identify for each couple of lexemes derivational patterns that are close to the intuition of the morphologists.
The COMPRISE Cloud Platform

This paper presents the COMPRISE cloud platform that is developed in the H2020 project. We present an overview of the COMPRISE project, its main goals, components, and how the cloud platform fits in the context of the overall project. The COMPRISE cloud platform is presented in more detail – main users, use scenarios, functions, implementation details, and how it will be used by both COMPRISE’s targeted audience and the broader language-technology community.
Developing Language Resources with Citizen Linguistics in Austria – A Case Study

Language resources are a major ingredient for the advancement of language technologies. Citizen linguistics can help to create language resources and annotate language resources, not only for the improvement of language technologies, such as machine translation but also for the advancement of linguistic research. The (language) resources covered in this article are a corpus related to the Question of the Month project strand, which was initially aimed at co-creation in citizen linguistics and a partially annotated database of pictures of written text in different languages found in the public sphere. The number of participants in these project strands differed significantly. Especially those activities that were related to data collection (and analysis) had a significantly higher number of contributions per participant. This especially held true for the activities with (prize) incentives. Nevertheless, the activities of the Question of the Month could reach a higher number of participants, even after the co-creation approach was no longer followed. In addition, the Question of the Month brought research gaps and new knowledge to light and challenged existing paradigms and practices. These are especially important for the advancement of scholarly research. Citizen linguistics can help gather and analyze linguistic data, including language resources, in a short period of time. Thus, it may help increase the access to and availability of language resources.
IndicSpeech: Text-to-Speech Corpus for Indian Languages

India is a country where several tens of languages are spoken by over a billion strong population. Text-to-speech systems for such languages will thus be extremely beneficial for wide-spread content creation and accessibility. Despite this, the current TTS systems for even the most popular Indian languages fall short of the contemporary state-of-the-art systems for English, Chinese, etc. We believe that one of the major reasons for this is the lack of large, publicly available text-to-speech corpora in these languages that are suitable for training neural text-to-speech systems. To mitigate this, we release a 24 hour text-to-speech corpus for 3 major Indian languages namely Hindi, Malayalam and Bengali. In this work, we also train a state-of-the-art TTS system for each of these languages and report their performances. The collected corpus, code, and trained models are made publicly available.
Role for neuronal insulin resistance in neurodegenerative diseases

Impairment of insulin signaling in the brain has been linked to neurodegenerative diseases. To test the hypothesis that neuronal insulin resistance contributes to defects in neuronal function, we have performed a detailed analysis of brain/neuron-specific insulin receptor knockout (NIRKO) mice. We find that NIRKO mice exhibit a complete loss of insulin-mediated activation of phosphatidylinositol 3-kinase and inhibition of neuronal apoptosis. In intact animals, this loss results in markedly reduced phosphorylation of Akt and GSK3β, leading to substantially increased phosphorylation of the microtubule-associated protein Tau, a hallmark of neurodegenerative diseases. Nevertheless, these animals exhibit no alteration in neuronal proliferation/survival, memory, or basal brain glucose metabolism. Thus, lack of insulin signaling in the brain may lead to changes in Akt and GSK3β activity and Tau hyperphosphorylation but must interact with other mechanisms for development of Alzheimer's disease.
Inducing Universal Semantic Tag Vectors

Given the well-established usefulness of part-of-speech tag annotations in many syntactically oriented downstream NLP tasks, the recently proposed notion of semantic tagging (Bjerva et al. 2016) aims at tagging words with tags informed by semantic distinctions, which are likely to be useful across a range of semantic tasks. To this end, their annotation scheme distinguishes, for instance, privative attributes from subsective ones. While annotated corpora exist, their size is limited and thus many words are out-of-vocabulary words. In this paper, we study to what extent we can automatically predict the tags associated with unseen words. We draw on large-scale word representation data to derive a large new Semantic Tag lexicon. Our experiments show that we can infer semantic tags for words with high accuracy both monolingually and cross-lingually.
A phylogenetic analysis of Schiedea and Alsinidendron (Caryophyllaceae: Alsinoideae): implications for the evolution of breeding systems

Phylogenetic analysis of Schiedea and Alsinidendron (Caryophyllaceae), a monophyletic lineage endemic to the Hawaiian Islands, produced six equally most parsimonious trees with 132 steps using morphological characters. Four major clades were found in all trees. Breeding system characters were excluded from the analysis because of the likelihood that dimorphism (gynodioecy, subdioecy, dioecy) has evolved in parallel in Schiedea, although subsequent inclusion of these characters had little effect on topology. Dimorphism is found in the two clades occurring primarily in dry habitats. Mapping of breeding systems on the phylogeny suggests that dimorphism has probably evolved on two or more occasions, depending on the number of character states and whether the character is treated as ordered or unordered. One to several reversals from dimorphism to hermaphroditism have also occurred. Dimorphic species occur only in dry habitats, but mapping of habitat on the phylogeny suggests that hermaphroditic species originally may have invaded dry habitats without evolving a dimorphic breeding system. Ecological shifts to very wet habitats appear to have favored the evolution of autogamy, which has occurred independently in the two clades largely restricted to mesic or wet habitats. The striking variation in breeding systems found in Schiedea and Alsinidendron appears to result in large part from the invasion of diverse habitats in the Hawaiian Islands following colonization by the ancestor of this lineage. Dioecy, the presence of separate pistillate (female) and staminate (male) plants in a population, occurs in about 4% of all flowering plants (Yampolsky and Yampolsky 1922). Numerous theoretical and empirical studies have addressed the question of why dioecy should evolve, given that female or male individuals suffer a 50% loss in reproductive potential relative to hermaphrodites. One set of arguments emphasizes the importance of inbreeding depression. In models developed by Lloyd (1975a) and Charlesworth and Charlesworth (1978), females may spread in populations if both inbreeding depression and selfing rates are high. Under these conditions, females spread because the.progeny of females, which are always outcrossed, will have higher fitness than the progeny of hermaphrodites, which self to varying degrees. If females produce more seeds than hermaphrodites, which seems likely on the basis of resource reallocation, they may spread even when inbreeding depression and selfing rates of hermaphrodites are lower. Other models (Charnov 1982) emphasize the importance of shifts in resource allocation. Empirical studies indicate the widespread occurrence of inbreeding depression (Schemske 1983; Schoen 1983; Sakai et al. 1989; Dudash 1990; Johnston 1992), and studies of selfing rates in several species with high inbreeding depression indicate that unisexual individuals should be favored by selection (Kohn 1988; Sakai and Weller, unpubl. data). Overall, little evidence has accumulated suggesting that either
Overview of the Fourth BUCC Shared Task: Bilingual Dictionary Induction from Comparable Corpora

The shared task of the 13th Workshop on Building and Using Comparable Corpora was devoted to the induction of bilingual dictionaries from comparable rather than parallel corpora. In this task, for a number of language pairs involving Chinese, English, French, German, Russian and Spanish, the participants were supposed to determine automatically the target language translations of several thousand source language test words of three frequency ranges. We describe here some background, the task definition, the training and test data sets and the evaluation used for ranking the participating systems. We also summarize the approaches used and present the results of the evaluation. In conclusion, the outcome of the competition are the results of a number of systems which provide surprisingly good solutions to the ambitious problem.
Patterns of Rhizosphere Microbial Community Structure Associated with Co-Occurring Plant Species

1 Rhizosphere populations of free-living bacteria and fungi associated with particular co-occurring plants were characterized to examine patterns of microbial community structure in natural plant communities. Soil was collected from three co-occurring perennial plant pairs in an undisturbed field at Smoot Hill Biological Reserve, Pullman, Washington, USA, and from three different perennial plant pairs in an old-field community in Durham, North Carolina, USA. 2 Bacteria and fungi isolated from these rhizosphere soils were tested for their ability to utilize various carbon substrates, their tolerance of antibiotics, and their sensitivity to osmotic and metal stresses. Multivariate analysis of physiological characteristics showed that rhizosphere microbial populations associated with particular plant pairs were significantly different from one another. Plots of the first and second linear discriminative functions from a canonical analysis showed clustering of bacterial and fungal physiological characteristics according to plant pair. 3 Replicates of particular plant pairs were planted into both greenhouse and field experiments to test whether bacterial community structure was influenced by different plant pairs. Repeated profile analyses showed that initially similar rhizosphere bacterial communities differentiated in both the greenhouse and field experiments and that these differences were associated with plant pairs. 4 The data suggest structure in rhizosphere populations of free-living bacteria and fungi can be influenced by plants. They provide a first step in understanding the link between the structure and function of natural plant and microbial communities.
Nutritional and management related interactions with iron-deficiency stress response mechanisms

Abstract Iron (Fe) deficiency symptoms develop in many agricultural and horticultural settings and generally occur when susceptible genotypes are grown in calcareous soils where Fe availability is limited. However, in some situations, Fe deficiency develops as a result of biological interactions with factors other than limited available Fe. We review physiological explanations for some factors known to interact with iron-deficiency stress. The discussion includes interactions with macronutrients and micronutrients, management factors such as grazing and companion cropping, and symbiotic nitrogen fixation. We also refer to several field observed interactions with Fe deficiency in soybean [Glycine max (L.) Merr. ], where physiological explanations are yet to be identified. These include interactions with seeding rate and application of the herbicide glyphosate on glyphosate tolerant varieties. We believe that elucidation of additional physiological answers for field observations are critical to efficient and economic viability of world food production.
Distribuição espaço-temporal da raiva bovina em Minas Gerais, 1998 a 2006

Epidemiological data of bovine rabies were evaluated after analyzing 6,873 files collected in Minas Gerais state, from 1998 to 2006. Direct Immunofluorescence was performed to diagnosis the disease. The temporal distribution of the disease was analyzed after tables and graphics were made using the software Excel 2003. A mapping diagnosis was built using the applicatory Tabwin 1.4. It was observed an annual decreasing tendency in the number positive diagnosis (Y= -41.133x+544.89). A higher percentage of positive diagnosis for rabies was observed from May to July. There was a variation in the number of counties in which bovine rabies was diagnosed during the studied period and it maintained a decreasing trend (Y= -7.0833x+166.64), with expansion of the disease in direction of "Triângulo Mineiro" counties.
Fermentative Production of L-Proline with Auxotrophs of Corynebacterium glutamicum

Two auxotrophic mutants of Corynebacterium glutamicum were found to produce a large amount of l-proline in the culture medium. High concentration of MgSO4 or MnSO4 in the medium stimulated the l-proline production by an isoleucine auxotroph. Optimum concentration of l-isoleucine was 200 μg/ml, and the higher concentration of l-isoleucine reduced the l-proline production. The auxotroph produced 14.8 mg/ml of l-proline when cultured in a medium containing 12% glucose, 1.7% NH4C1,0.6% MgSO4·7H2O, 0.06% MnSO4·4H2O and 200 μg/ml of l-isoleucine. The other mutant, whose growth responds to the bases of nucleic acids, produced 7 to 13 mg/ml of l-proline in a cane molasses (15%, as glucose concentration)-medium containing 2% of the acid-hydrolyzate of soybean meal. The l-proline production by this mutant increased to a level of 27 to 31 mg/ml when the growth was suppressed by the addition of 4% NH4C1 to the medium, or by the addition of 2 mg/ml of polyoxyethylenestearylamine, a surfactant, to a culture at an appro.
Registration of an Early-Maturing Peanut Germplasm ICGV 86015

ICGV 86015, a spanish-type peanut (Arachis hypogaea L. subsp. fastigiata Waldron var. vulgaris Harz) germplasm (Reg. no. GP-73, P1 585005) was bred at the Asia Center of the International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Patancheru, India. It was identified and released as an early-maturing widely adapted high-yielding breeding line (3) by the Plant Materials Identification Committee of ICRISAT in 1993. This improved germplasm has been designated as Hung Loc 25 (HL 25) in Vietnam, where, in 33 field experiments and 6 trials involving 344 farming families, it was found most suitable for intercropping with cassava (Manihot esculenta Crantz) and maize (Zea mays L.) in the southeast coastal and southeastern regions of the country (4). It is proposed for release as BARD 92 in Pakistan for double cropping with wheat (Triiicum aestivum L.) and is particularly adapted to the barani (rainfed) conditions of the Pothwar area in the country.
Life Histories and Community Stability

In stable communities a major fraction of species are longevous; perennial plants in terrestrial, and largely benthic invertebrates in marine situations. The question is raised whether the relationship is fortuitous or depends on positive feedback. Available evidence often seems insufficient to rule out a third alternative, that it is tautological. See full-text article at JSTOR