Miracle-dz/UniFAR-FTUs huggingface dataset:
Healthcare ProfessionalÃ¢ÂÂs Utilization of Physical Exercise as a Strategy to Prevent NCDs in Ethiopian Public Sector Hospitals

Background: Despite the recognized benefits of physical exercise, including a reduction of health risk factor indicators, illness and death related to Non-Communicable Diseases (NCDs) (cardiovascular disease, diabetes, hypertension, cancer), the extent of its recognition and use as a prevention strategy by healthcare professionals working in Ethiopian referral hospitals is unknown. Objective: This study explored healthcare professionals’ use of Physical exercise as a non-communicable disease Prevention Strategies in the Ethiopian public sector Healthcare System. Methods: A cross-sectional study was conducted among (N=312) health care professionals (nurses, physicians and medical managers) in 13 Ethiopian referral hospitals. Results: The results indicated thatthree quarters (78%) of healthcare professionals working in Ethiopian hospitals are not using physical exercise as a strategy to prevent NCDs. Increased specialization (AOR=20.203, p<0.001), many service years (AOR=0.041, p=0.014), young age (AOR=19.871, p<0.001), and being men (AOR=0.269, p<0.001) were predictors of using physical exercise as a strategy for NCDs prevention. Conclusion: Healthcare professionals’ utilization of physical exercise as a strategy for NCDs prevention was inadequate in Ethiopia. Given the increasing burden of NCD disease in Ethiopia, training nurses, physicians and medical managers to use physical exercise as an NCD prevention strategy is essential at undergraduate level for as well as through specialized courses once they are qualified.
PHYTOMITOGEN-INDUCED HYDROLYSIS OF INOSITOL LIPIDS IN AN INTERLEUKIN 2-PRODUCING HUMAN T CELL LEUKEMIA LINE, JURKAT-FHCRC

The human T cell leukemia line designated Jurkat-FHCRC produces relatively high quantities of interleukin 2 (IL-2) after a 6-24 h stimulation with either phytohemagglutinin (PHA) or concanavalin A (Con A) (9). In order to understand the early processes in Jurkat cells which are set in motion by the lectins, we examined the effect of the lectins on the hydrolysis of inositol lipids in Jurkat cells. In my0-[2-3H]-inositol-prelabeled Jurkat cells, PHA and Con A induced a 3.4-fold accumulation of myo-[2-3H]inosito1 phosphate during 15 min incubation at 37°C in the presence of 5 mM LiCl. Since Li““ is a potent inhibitor of and the accumulated myo-[2-3H]inositol phosphate can only arise after phospholipase C attack on cellular [3H]inositol lipids, the results indicate that the plant lectins induce the hydrolysis of inositol lipids in Jurkat cells. min
Medication adherence and its predictors among patients with heart failure

Background: Medication adherence is a complex behavioral pattern affecting treatment success. A stepping stone to improve medication adherence is to determine its contributing factors. Objectives: This study intended to evaluate medication adherence and its predictors among patients with heart failure in Mazandaran Heart Center, Sari, Iran. Methods: This cross-sectional study was conducted on 300 patients with heart failure who were hospitalized from January to March 2015. Sampling was done through the census method. Data were collected using the Morisky Medication Adherence Scale and were analyzed using the Chi-square test and logistic regression analysis. Results: The mean score of treatment adherence was 5.82 ± 2.54. Medication adherence had a significant correlation with education level (P = 0.012), number of children (P = 0.013), comorbidity (P = 0.002), ejection fraction (P = 0.046), and the number of tablets used per day (P = 0.001). However, it was not significantly correlated with age, gender, employment status, place of residence, income level, and the number of hospitalizations for heart failure (P > 0.05). Logistic regression analysis showed that none of the demographic and clinical characteristics was a significant predictor of medication adherence. Conclusion: Medication adherence is affected by different factors such as education level, number of children, comorbidity, disease severity, and the number of tablets used per day. Nurses need to take these factors into account when developing care plans and patient education programs.
An unusual case of scleroderma lung disease

ABSTRACT Systemic sclerosis is a disease characterized by autoimmunity, vasculopathy and fibrosis. Interstitial lung disease and pulmonary hypertension are the most common manifestations of lung disease in systemic sclerosis and, together, are the leading cause of mortality in systemic sclerosis. This study presents a case of a young man with limited systemic sclerosis and no smoking history who underwent chest imaging for suspicion of interstitial lung disease and was found to have extensive emphysema. This case outlines the importance of recognizing the presence of combined fibrosis and emphysema in those with systemic sclerosis.
Physio- und Ergotherapie in der Akut-Neurologie

Zusammenfassung Ein integraler Bestandteil der Behandlung neurologischer Patienten ist die Therapie von Funktionsstörungen, die durch neurologische Krankheiten wie z. B. einen Schlaganfall hervorgerufen werden. Das Therapieziel der Physiotherapie besteht darin, bettlägerige Patienten durch aktive Bewegungs- und Gleichgewichtsübungen wieder zu mobilisieren und im Zusammenwirken mit ergotherapeutischen Übungsbehandlungen in die Lage zu versetzen, Verrichtungen alltagrelevanter Tätigkeiten möglichst selbstständig wieder ausführen zu können. Darüber hinaus wird durch multimodale aktiv-assistive Übungen sekundären Versteifungen bewegungseingeschränkter Gliedmaßen entgegengewirkt. Grundlage dieser Behandlungen sind neurophysiologisch basierte Modellvorstellungen über die postläsionelle Plastizität des Gehirns. Es wurden Skalen entwickelt, mit denen neurologische Funktionsstörungen und deren Rückbildung parametrisch und untersucherunabhängig erfasst werden können. Damit kann der Funktionszustand der Patienten dokumentiert und zwischen Behandlungseinrichtungen kommuniziert werden. Außerdem kann so die Effektivität physio- und ergotherapeutischer Maßnahmen in der Akut-Neurologie überprüft werden.
Kunnskapsgrunnlaget for behandlingslinjer – en foreløpig oversikt.

handlingsplaner som spesifiserer viktige trinn i behandlingen av pasienter med definerte kliniske problemer. Behandlingslinjer har vært benyttet i ulik grad ved norske sykehus og er nå et satsingsområde for Helse Sør-Øst RHF. I dette notatet angir vi noen kilder og verktøy som kan være aktuelle i arbeidet med behandlingslinjer. Metode: Vi søkte etter systematiske oversikter om effekten av behandlingslinjer og fokuserte på oversikter om effekten av behandlingslinjer generelt. På grunn av den forenklede metoden som ble brukt, har vår gjennomgang av dokumentasjonen klare metodologiske svakheter både i forhold til utvalg og vurdering av kvaliteten på oversiktene. Resultat: • Vi fant én Cochrane-protokoll for en kommende systematisk oversikt og to ferdige systematiske oversikter om den generelle effekten av behandlingslinjer. Cochrane-protokollen vil ventelig gi en god systematisk oversikt over forskningsgrunnlaget for behandlingslinjer. Publisering er planlagt i juni/juli 2008. Konklusjonene i de to foreliggende oversiktene er delvis motstridende, og kvaliteten er usikker. • Vi fant (fortsetter på baksiden) Kunnskapsgrunnlaget for behandlingslinjer – en foreløpig oversikt
Risk of survival, establishment and spread of Batrachochytrium salamandrivorans (Bsal) in the EU

Abstract Batrachochytrium salamandrivorans (Bsal) is an emerging fungal pathogen of salamanders. Despite limited surveillance, Bsal was detected in kept salamanders populations in Belgium, Germany, Spain, the Netherlands and the United Kingdom, and in wild populations in some regions of Belgium, Germany and the Netherlands. According to niche modelling, at least part of the distribution range of every salamander species in Europe overlaps with the climate conditions predicted to be suitable for Bsal. Passive surveillance is considered the most suitable approach for detection of Bsal emergence in wild populations. Demonstration of Bsal absence is considered feasible only in closed populations of kept susceptible species. In the wild, Bsal can spread by both active (e.g. salamanders, anurans) and passive (e.g. birds, water) carriers; it is most likely maintained/spread in infected areas by contacts of salamanders or by interactions with anurans, whereas human activities most likely cause Bsal entry into new areas and populations. In kept amphibians, Bsal contamination via live silent carriers (wild birds and anurans) is considered extremely unlikely. The risk‐mitigation measures that were considered the most feasible and effective: (i) for ensuring safer international or intra‐EU trade of live salamanders, are: ban or restrictions on salamander imports, hygiene procedures and good practice manuals; (ii) for protecting kept salamanders from Bsal, are: identification and treatment of positive collections; (iii) for on‐site protection of wild salamanders, are: preventing translocation of wild amphibians and release/return to the wild of kept/temporarily housed wild salamanders, and setting up contact points/emergency teams for passive surveillance. Combining several risk‐mitigation measures improve the overall effectiveness. It is recommended to: introduce a harmonised protocol for Bsal detection throughout the EU; improve data acquisition on salamander abundance and distribution; enhance passive surveillance activities; increase public and professionals’ awareness; condition any movement of captive salamanders on Bsal known health status.
ASSESSMENT OF ANTIMICROBIAL ACTIVITY OF ETHANOLIC EXTRACTION OF USNEA GHATTENSIS AND USNEA UNDULATA

The fungal partner of lichens produces a great variety of biologically active metabolites such as antibiotic, antiviral, anti-inflammatory and many others. Antimicrobial is a substance which either inhibits the growth of micro-organism or kills the microbes. The pathogenic microorganisms causing number of diseases in plants and animals have developed resistance against many commonly available chemicals and antibiotics. Lichens are the combination of two life forms algae and fungi. A large number of lichens are known for the source of important secondary metabolites. The present study aims at the antimicrobial properties of two species of Usnea belonging to the largest family Parmeliaceae. The antibacterial activity of two species of Usnea was tested against six organisms such as Staphylococcus aureus, Streptococcus pneumoniaee, Salmonella typhi, Escherichia coli, Vibrio choleraee, Bacillus coagulans. Both species of Usnea had shown inhibitory activity against all pathogen but to different extent. These two species of Usnea are found in large quantity in Mullayangiri of Karnataka and these two species can be used sustainably in the preparation of antimicrobials.
Educator’s Readiness for 21st Century Education

: Most graduates today lack skills to equip themselves to cope with 21st century workplace demands due to lack of critical thinking skills, problem solving skills and communication skills. Reports indicate that this could be due to the education system that has not facilitated the educator’s preparatory abilities to engage in 21st century teaching systems. Most educators are equipped with pedagogical knowledge and have some professional training in teaching. However, 21st century education demands more than merely teaching through chalk and talk. In the Malaysian Education Blueprint for Higher Education 2015-2025, ten shifts to transform conventional teaching were highlighted and this included globalised online learning and transformed higher education delivery. While the blueprint provides a holistic overview of the government’s aspiration for the future workforce of this nation, questions such as whether old school educators are able to grip with the fast pace of technological advancement and whether institutions of learning are well-equipped to embrace the technology by means of the physical classroom environment and the virtual platform that are available for use today is still evasive. This study therefore, intends to address the issues underlining educator’s readiness for 21st century education bearing in mind the national education agenda and the students techno-savvy abilities compared to their educators. Suggestions and recommendations are also discussed to provide for educators who are better equipped to handle the changing scene of education in this 21st century.
Maternal Serum Vascular Endothelial Growth Factor in Patients with Preeclampsia

Background: Vascular endothelial growth factor and placental growth factor levels were significantly lower in patients of sever or early onset (34 weeks or less gestational age at onset of PET) pre-eclampsia than in controls. Aim of the Work:Will there be a rise in serum vascular endothelial growth factor in pregnant women suffering from preeclampsia than in normotensive pregnant women. Patients and Methods: 150 pregnant women from 28 weeks of gestation till term will be enrolled into this comparative clinical trial at the time of their antenatal visit to the outpatient department of obstetrics and gynecology Ain Shams University maternal hospital. Results: We recruited 150 pregnant women after 28 weeks of gestation and they were classified into 3 groups: Group1:50 pregnant women with mild preeclampsia from 28 weeks of gestation till term, Group2: 50 pregnant women with severe preeclampsia from 28 weeks of gestation till term and Group 3: 50 normal pregnant women serving as controls. Conclusion: We conclude that serum VEGF level measured after 28 weeks of gestation can be used as a predictor for preeclampsia and its degrees (mild and severe) with high sensitivity and specificity.
Is robotic pancreatectomy indicated for patients with pancreatic cancer

Minimally invasive pancreatic surgery (MIPS) is becoming more popular in the recent years. Robotic pancreatic surgery represents an important step, mostly for Whipple procedures, in order to reproduce the same surgical steps performed in open surgery and to facilitate the access to MIPS even by surgeons without a large experience in laparoscopic surgery. The short-term results of pancreatic robotic surgery are comparable with the one obtained by the traditional open surgery, even if the peri-operative costs, still represent a problem. Very few data are currently available regarding the long-term oncologic outcome of robotic pancreatectomy for pancreatic cancer. For this reason, more and larger studies, with a long follow-up are necessary to define the oncologic role and safety of robotic pancreatectomies.
Responses of Engelmann spruce to inoculation with Leptographium abietinum, a symbiotic fungus of the North American spruce beetle

Symbiotic fungi associated with tree-killing bark beetles can alter host-tree physiology with consequences for tree survival, and symbiont genetic variation and environmental variability may impact these interactions. Here, we test whether multiple genetically distinct isolates of a symbiotic fungus (Leptographium abietinum (Peck) M.J. Wingf. ) associated with North American spruce beetle (Dendroctonus rufipennis (Kirby, 1837)) vary in their ability to manifest defensive responses consistent with disease symptoms in seedlings of Engelmann spruce (Picea engelmannii Parry ex Engelm.), a primary host-tree species for the beetle–fungus complex in North America. Our experiments incorporate variation in both host-tree water availability and host defenses (phloem monoterpene concentration). Three central findings emerged: (i) isolates varied considerably in their effects on host trees — inoculation with L. abietinum isolates from Colorado caused significantly larger phloem lesions than isolates from Wyoming, though all isolates caused phloem oxidation; (ii) neither water availability nor spruce phloem monoterpene concentrations impacted lesion formation; and (iii) both inoculation with L. abietinum and water deficit inhibited the formation of callus tissue at wound sites. We conclude that L. abietinum isolates vary in their virulence and that inoculation is not lethal but may benefit beetles by altering tree defensive responses.
Adaptation and Validation of a Short French Version of the Affective Style Questionnaire

Emotion regulation (ER) plays an important role in psychological well-being. Therefore, its valid assessment is a crucial step in the investigation of the interindividual differences linked to effective ER. Adapting and validating a French version of the Affective Style Questionnaire (ASQ) and test its predictive power in detecting mood disorders. We administered to a large sample (1226 participants) a brief (12 items) French version of the ASQ. We tested convergent validity by investigating its links with mindfulness trait and life satisfaction. Moreover, using a machine learning approach, we tested whether ER features could predict the presence of self-reported mood disorders. We demonstrated a good convergent validity by reproducing the original factor structure. We also showed that the adjusting dimension, referring to the ability to flexibly modulate our emotional experience according to contextual demands, was associated with concurrent markers of psychological well-being such as dispositional mindfulness and life satisfaction. Moreover, this strategy was also related to a low probability of subjectively reporting suffering from a mood disorder. Our results highlighted adjusting as an adaptive ER strategy. Practical implications for psychotherapeutic approaches of mood disorders are discussed.
A Division of Labor in the Recruitment and Topological Organization of a Bacterial Morphogenic Complex

Bacteria come in an array of shapes and sizes, but the mechanisms underlying diverse morphologies are poorly understood. The peptidoglycan (PG) cell wall is the primary determinant of cell shape. At the molecular level, much of the studied morphological variation results from the regulation of PG synthesis enzymes involved in elongation and division. These enzymes are spatially controlled by cytoskeletal scaffolding proteins, such as FtsZ, MreB, and DivIVA, that both recruit and organize the PG synthesis complex. How then do cells define alternative morphogenic processes that are distinct from cell elongation and division? To address this question, we have turned to the specific morphotype of Alphaproteobacterial prosthecae, or “stalks”. Stalk synthesis is a specialized form of zonal growth, which requires PG synthesis in a spatially constrained zone to extend a thin cylindrical projection of the cell envelope. The morphogen SpmX defines the site of stalk PG synthesis, but SpmX is a PG hydrolase. How then does a non-cytoskeletal protein, SpmX, define and constrain PG synthesis to form stalks? Here we report that SpmX and the bactofilin BacA act in concert to regulate stalk synthesis in Asticcacaulis biprosthecum. We show that SpmX acts to recruit BacA to the site of stalk synthesis. BacA then serves as a stalk-specific topological organizer that anchors the PG synthesis complex, including its recruiter SpmX, to the base of the stalk, where stalk PG synthesis occurs. In the absence of BacA, cells produce “pseudostalks” that are the result of unconstrained PG synthesis correlated with the mislocalization of SpmX. Finally, we show that BacA is required to inhibit the default function of PG synthesis machinery in cell elongation/division and to prevent DNA entry at the site of stalk synthesis defined by SpmX. Therefore, the protein responsible for recruitment of a morphogenic PG remodeling complex is uncoupled from the protein that topologically organizes the complex.
SAZD: A Low Computational Load Coded Distributed Computing Framework for IoT Systems

Coded distributed computing (CDC) can overcome the problem that the computation of matrix multiplication with an extremely huge dimension cannot be executed in a single Internet-of-Things (IoT) node. All the encoding of existing CDC schemes are based on the linear combination (LC) to generate independent computation tasks, which introduces a heavy computational load, including a significant volume of expensive multiplications (compared with inexpensive additions) and even more expensive divisions to the encoding and decoding phases. Note that the number of elementwise multiplications of the LC operation during the encoding phase is <inline-formula> <tex-math notation="LaTeX">$N$ </tex-math></inline-formula> times that of the original computation task, where <inline-formula> <tex-math notation="LaTeX">$N$ </tex-math></inline-formula> denotes the number of worker nodes. In this article, to avoid expensive multiplications introduced by LC, a fresh new CDC framework based on shift-and-addition (SA) over the real field is proposed. In addition, to avoid the expensive matrix inverse operation (divisions) in the decoding phase, zigzag decoding (ZD) is incorporated. The proposed scheme, which combines SA and ZD and is hence named SAZD-based CDC, avoids expensive multiplications and divisions in both the encoding and decoding phases. It targets the following simultaneous objectives: an arbitrary <inline-formula> <tex-math notation="LaTeX">$K$ </tex-math></inline-formula> out of <inline-formula> <tex-math notation="LaTeX">$N$ </tex-math></inline-formula> generated computation tasks is independent and can recover the original computation tasks with the ZD algorithm, and the shift distance is small so as to cause a light additional computational load in the computation phase. Both analysis and practical study show that compared to the LC-based CDC, the SAZD-based CDC significantly reduces the computational load.
Marco de referencia para la publicación de datos abiertos comprensibles basado en estándares de calidad

Los portales donde se publican datos abiertos son una oportunidad para democratizar el acceso a la informacion generada por las instituciones del sector publico, asi como potenciar su reutilizacion. Esta reutilizacion de datos abiertos permite el desarrollo de nuevos productos y servicios digitales, creando oportunidades de desarrollo social y economico. Sin embargo, la reutilizacion de estos datos se enfrenta con diversas barreras en su expansion, debido a diversos problemas relacionados con la calidad de datos que van desde la incompletitud de los datos hasta la falta de actualizacion de los mismos. En concreto, un criterio relevante de calidad de datos abiertos es la comprensibilidad, ya que un proceso de interpretacion erronea de los datos abiertos provocara ambiguedades o malentendidos que desmotivara su reutilizacion. Por esta razon, un aspecto importante en el acceso a los datos abiertos son sus metadatos, es decir aquellos datos que describen el contenido del conjunto de datos abiertos, cuya finalidad es facilitar su comprension. Con el fin de mejorar la comprensibilidad de los datos abiertos, las propuestas actuales se centran en la evaluacion de los datos ya publicados, no existiendo propuestas que evaluen como se puede mejorar la comprensibilidad de los datos abiertos desde los sistemas de informacion de origen del dato. Esta tesis doctoral revisa y analiza los trabajos de investigacion en datos abiertos mediante el desarrollo de un mapeo sistematico, incluyendo un analisis de barreras en la reutilizacion de datos abiertos, asi como buenas practicas y estandares aplicables al proceso de publicacion de datos en formatos abiertos. Este analisis sistematico de trabajos previos de investigacion ha servido como punto de partida para la definicion de un marco de referencia que permita la publicacion de datos abiertos comprensibles. En este marco de referencia se considera la comprensibilidad de los datos abiertos mediante la gestion de los metadatos desde las mismas fuentes de datos en los sistemas de informacion de origen, incluyendo el concepto de fichero de datos maestros de apertura. Finalmente, cabe destacar que, a traves de la aplicacion del metodo de investigacion-accion, se ha validado el marco de referencia, utilizando entrevistas y grupos de discusion con varios administradores de portales de datos abiertos.