Miracle-dz/UniFAR-FTUs huggingface dataset:
Sexuelle Identität, sexuelle Attraktion und sexuelles Verhalten – Dimensionen sexueller Orientierungen in der Survey-Forschung

Zusammenfassung Einleitung: Nach aktueller Forschungslage empfiehlt sich die Erfassung der Vielfältigkeit sexueller Orientierungen über die Dimensionen sexuelle Identität, sexuelle Attraktion und sexuelles Verhalten, zumal empirische Studien zeigen, dass für einen Anteil von Personen die Dimensionen nicht kongruent (übereinstimmend) beantwortet werden. Bei der Interpretation von Forschungsergebnissen muss daher die Operationalisierung von sexuellen Orientierungen berücksichtigt werden. Forschungsziele: Ziel der Studie ist es, anhand einer deutschen Stichprobe verschiedene Muster der drei Dimensionen sexueller Orientierungen bei Männern und Frauen zu verdeutlichen. Methoden: Es wurden anhand der Daten von 498 Männern und 481 Frauen mit heterosexueller, bisexueller und homosexueller Identität Muster kongruenter (übereinstimmender) und inkongruenter (nicht übereinstimmender) Angaben zu den Dimensionen sexueller Orientierungen analysiert. Ergebnisse: Ein Großteil der Männer (94.9 %) und Frauen (95.8 %) machte kongruente Angaben in den drei Dimensionen sexueller Orientierungen. Personen mit bisexueller Identität zeigten am häufigsten nicht übereinstimmende Antwortmuster bzw. Inkongruenzen (Männer: 100 %, Frauen: 90.0 %). Kongruente homosexuelle Orientierungen waren häufig mit einer Variabilität innerhalb der drei Dimensionen verbunden, die auch nur vorwiegend gleichgeschlechtliche sexuelle Attraktion und sexuelles Verhalten beinhalten kann (Männer: 60.0 %, Frauen: 87.5 %), während kongruente heterosexuelle Orientierungen öfter als ausschließliche Bezogenheit auf das andere Geschlecht beschrieben wurden (Männer: 89.2 %, Frauen: 78.0 %). Schlussfolgerung: Im Vergleich zu Personen mit heterosexueller Identität zeigte sich bei Männern und Frauen mit homosexueller Identität eine größere Variabilität zwischen sexueller Identität und Attraktion und/oder zwischen sexueller Identität und Verhalten. Limitationen quantitativer Forschung hinsichtlich der Abbildung der Komplexität der menschlichen Sexualität sind kritisch zu diskutieren.
Impacto da Medida Provisória nº 579/2012 sobre o Beta das Empresas Brasileiras do Setor Eletétrico

A promulgacao da Medida Provisoria no. 579/2012 teve por objetivo viabilizar a reducao do custo da energia eletrica para o consumidor brasileiro. Entretanto, trouxe diversas consequencias para este setor, destacando-se as incertezas quanto as novas regras de renovacoes de concessoes do setor e as indenizacoes dadas as empresas pelo governo por conta de ativos nao totalmente depreciados em relacao ao 4o. Ciclo de revisoes tarifarias das distribuidoras. Assim, no presente trabalho, buscou-se verificar empiricamente o impacto da referida Medida Provisoria no risco de mercado do setor eletrico. Especificamente, foi analisado o risco sistemico por meio do beta das empresas em questao. A partir do modelo de regressao robusta para uma amostra de 16 empresas reguladas, os resultados apontaram para o aumento dos betas das empresas do setor eletrico apos a MP579/2012, o que influenciou positivamente no risco sistematico das mesmas. Alem disso, verificou-se que as empresas geradoras de energia apresentaram um maior nivel de risco do que as distribuidoras e transmissoras apos o advento da MP579/2012.
The importance of differentiating gelsolin isoforms.

4. American Thoracic Society/Centers for Disease Control and Prevention. Targeted tuberculin testing and treatment of latent tuberculosis infection. Am J Respir Crit Care Med 2000;161:S221–S247. 5. O’Brien RJ, Spigelman M. New drugs for tuberculosis: current status and future prospects. Clin Chest Med 2005;26:327–340. 6. Nuermberger EL, Yoshimatsu T, Tyagi S, Williams K, Rosenthal I, O’Brien RJ, Vernon AA, Chaisson RE, Bishai WR, Grosset JH. Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis. Am J Respir Crit Care Med 2004; 170:1131–1134.
Indium Tin Oxide Plasma Frequency Dependence on Sheet Resistance and Surface Adlayers Determined by Reflectance FTIR Spectroscopy

Variable angle reflectance FTIR spectroscopy was used to investigate the optical properties of indium tin oxide (ITO) and fluorine-doped tin oxide (SFO) thin films in the near-IR spectral region. The reflectance data were used to determine the plasma frequency and the electronic scattering time using the Drude free-electron model, the dielectric function of ITO, and the two- and three-phase Fresnel equations for reflection. The reflectance, plasma frequency, and electronic scattering time of ITO thin films were found to be dependent on the sheet resistance. Surface adlayers were also found to affect the reflectance and the position of the plasma frequency of the ITO thin films. The reflectance and observed plasma frequency for the SFO thin films were lower than those for any of the ITO films studied.
Suggestion for a Fast Binary Sine/Cosine Generator

A combinational two-dimensional array for the rapid generation of sines and cosines is described. The array is a spatial realization of a continued product algorithm which uses multiplication by (1 + jEk2-k). Using 10-ns logic, it is estimated that 16-bit sines and cosines may be generated in less than 2 μs.
Exercise Distributed across Day and Night Does Not Alter Circadian Period in Humans

In rodents, increased activity due to running-wheel access is associated with a change in observed circadian period. In humans, exposure to exercise has failed to demonstrate similar effects on period. Methodological issues with prior studies such as light exposure during exercise, length of study, and method of measuring period confounded those evaluations of the effect of exercise on period in humans. In the present experiment, the authors examined the effect of exercise on period in 8 subjects using a 44-day within-subjects inpatient study. They used a 20-h forced desynchrony protocol, in which subjects were exposed to exercise across circadian phases under dim light conditions. Exercise consisted of three 45-min sessions per wake period on an ergometer. Target exercise intensity was ~65% of maximal heart rate. Intrinsic circadian period was measured using both core body temperature and hourly plasma melatonin samples. Consistent with previous reports, the authors find no effect of exercise on endogenous circadian period as measured by either core body temperature or melatonin. Exercise distributed across biological day and night does not appear to affect circadian period.
Mieux Contrôler les Fluctuations de Rendement grâce à une Meilleure Compréhension des Mécanismes d’Initiation et de Différenciation des Primordia Inflorescentiels du Bourgeon Latent de Vigne

Le determinisme de la formation de la grappe reste parmi les phenomenes les moins bien precises de la physiologie de la Vigne. La question a ete abordee de plusieurs facons mais les elements de reponse obtenus ne permettent pas encore de se faire une idee synthetique des mecanismes fondamentaux qui produisent l’apparition des primordia inflorescentiels (PI) en annee N-1 et qui pourraient regir jusqu’a 65 a 70% du rendement final en annee N. Notre etude s’est donc focalisee sur (i) la caracterisation du processus de formation des PI dans les bourgeons latents de vigne (Vitis vinifera L. Merlot) et la redefinition de la constitution du rendement, (ii) la comprehension des mecanismes d’initiation et de differenciation des PI et (iii) l’evaluation des impacts de differents facteurs (ABA exogene, lumiere et effeuillage) sur ces mecanismes.Cette etude integrale combinant des approches multi-echelles et multi-disciplinaires a permis dans un premier temps de mettre en evidence le determinisme de la phase d’induction inflorescentielle dans la construction du rendement en identifiant trois phases cles du processus de formation des PI et en y integrant une nouvelle notion qu’est le « degre de ramification des PI » ; puis dans un second temps, de proposer certains modes de regulation des mecanismes d’initiation et de differenciation des PI en identifiant trois types de marqueurs precoces de la fertilite potentielle : des marqueurs moleculaires (VvCLE25-1, VvTFL1a et VvMFT1), biochimiques (equilibre CKs/AIA, D-glucose et amidon), et environnementaux (ensoleillement et temperature journaliers cumules). L’ensemble des resultats pourra contribuer au developpement d’un outil predictif precoce de la « fertilite potentielle » (et donc du rendement probable maximum) afin de mieux guider et gerer la taille et les pratiques culturales.
Integrated NFV/SDN Architectures

Network Functions Virtualization (NFV) and Software-Defined Networking (SDN) are new paradigms in the move towards open software and network hardware. While NFV aims to virtualize network functions and deploy them into general purpose hardware, SDN makes networks programmable by separating the control and data planes. NFV and SDN are complementary technologies capable of providing one network solution. SDN can provide connectivity between Virtual Network Functions (VNFs) in a flexible and automated way, whereas NFV can use SDN as part of a service function chain. There are many studies designing NFV/SDN architectures in different environments. Researchers have been trying to address reliability, performance, and scalability problems using different architectural designs. This Systematic Literature Review (SLR) focuses on integrated NFV/SDN architectures, with the following goals: (i) to investigate and provide an in-depth review of the state of the art of NFV/SDN architectures, (ii) to synthesize their architectural designs, and (iii) to identify areas for further improvements. Broadly, this SLR will encourage researchers to advance the current stage of development (i.e., the state of the practice) of integrated NFV/SDN architectures and shed some light on future research efforts and the challenges faced.
Structural Studies on the Synchronization of Catalytic Centers in Glutamate Synthase*

The complex iron-sulfur flavoprotein glutamate synthase (GltS) plays a prominent role in ammonia assimilation in bacteria, yeasts, and plants. GltS catalyzes the formation of two molecules of l-glutamate from 2-oxoglutarate and l-glutamine via intramolecular channeling of ammonia. GltS has the impressive ability of synchronizing its distinct catalytic centers to avoid wasteful consumption ofl-glutamine. We have determined the crystal structure of the ferredoxin-dependent GltS in several ligation and redox states. The structures reveal the crucial elements in the synchronization between the glutaminase site and the 2-iminoglutarate reduction site. The structural data combined with the catalytic properties of GltS indicate that binding of ferredoxin and 2-oxoglutarate to the FMN-binding domain of GltS induce a conformational change in the loop connecting the two catalytic centers. The rearrangement induces a shift in the catalytic elements of the amidotransferase domain, such that it becomes activated. This machinery, over a distance of more than 30 Å, controls the ability of the enzyme to bind and hydrolyze the ammonia-donating substratel-glutamine.
Cerebral vasospasm following tumor resection

Objective To perform a systematic review of the literature of cases of vasospasm following tumor resection and to discuss possible etiologies, diagnosis and management of this complication. Methods A literature search was performed using relevant search key words to identify cases of ‘cerebral vasospasm’ as a complication following tumor resection. Articles were identified by searching MEDLINE and PubMed databases. Relevant cross references were added by manually searching the references of all retrieved articles. Results There were a total of 56 patients in our initial search but only 40 cases matched our inclusion criteria. Pituitary tumors and sellar area were the most common pathologies and location associated with this complication. Average time interval to development of symptomatic vasospasm was 8 days and mortality was high (30%). The most common encountered causative factors were vascular factors (vessel encasement, displacement and narrowing) and presence of blood in the basal cisterns in postoperative scans. Conclusions ‘Cerebral vasospasm’ after tumor resection is a rare but challenging complication with very high morbidity and mortality in reported cases. Vasospasm following brain tumor surgery shares some of the same clinical variables (time interval, causative factors, morbidity and death rates) of vasospasm after aneurysmal subarachnoid hemorrhage. A high index of suspicion is required for early diagnosis and prompt management which are key elements of final outcome.
The Efficiency of Race-Neutral Alternatives to Race-Based Affirmative Action: Evidence from Chicago&Apos;S Exam Schools

Several K-12 and university systems have adopted race-neutral affirmative action in place of race-based alternatives. This paper explores whether these plans are effective substitutes for racial quotas in Chicago Public Schools (CPS), which now employs a race-neutral, place-based affirmative action system at its selective exam high schools. The CPS plan is ineffective compared to plans that explicitly consider race: about three-quarters of the reduction in average entrance scores at the top schools could have been avoided with the same level of racial diversity. Moreover, the CPS plan is less effective at adding low-income students than was the previous system of racial quotas. We develop a theoretical framework that motivates quantifying the inefficiency of race-neutral policies based on the distortion in student preparedness they create for a given level of diversity and use it to evaluate several alternatives. The CPS plan can be improved in several ways, but no race-neutral policy restores minority representation to prior levels without substantially greater distortions, implying significant efficiency costs from prohibitions on the explicit use of race. (JEL H75, I21, I28, J15)
Functional changes in Duchenne muscular dystrophy

Objective: The aim of the study was to assess different outcome measures in a cohort of ambulant boys with Duchenne muscular dystrophy (DMD) over 12 months in order to establish the spectrum of possible changes in relation to age and steroid treatment. Methods: The study is a longitudinal multicentric cohort study. A total of 106 ambulant patients with DMD were assessed using the 6-minute walk test (6MWT) and North Star Ambulatory Assessment (NSAA) at baseline and 12 months. Clinical data including age and steroid treatment were collected. Results: During the 12 months of the study, we observed a mean decline of 25.8 meters in the 6MWT with a SD of 74.3 meters. On NSAA, the mean decline was 2.2 points with a SD of 3.7. Not all the boys with DMD in our cohort showed a decline over the 12 months, with young boys showing some improvement in their 6MWT and NSAA scores up to the age of 7. NSAA and the 6MWT had the highest correlation (r = 0.52, p < 0.001). Conclusions: This study provides longitudinal data of NSAA and 6MWT over a 12-month period. These data can be useful when designing a clinical trial.
mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer.

The mammalian target of rapamycin (mTOR) is a central regulator of G1 cell cycle protein synthesis that precedes commitment to normal cellular replication. We have studied the effect of cell cycle inhibitor-779 (CCI-779), a rapamycin ester that inhibits mTOR function, on the proliferation of a panel of breast cancer cell lines. Six of eight lines studied were sensitive (IC(50)< or = 50 nM) and two lines were resistant (IC(50)>1.0 microM) to CCI-779. Sensitive lines were estrogen dependent (MCF-7, BT-474, T-47D), or lacked expression of the tumor suppressor PTEN (MDA-MB-468, BT-549), and/or overexpressed the Her-2/neu oncogene (SKBR-3, BT-474). Resistant lines (MDA-MB-435, MDA-MB-231) shared none of these properties. CCI-779 (50 nM) inhibited mTOR function in both a sensitive and a resistant line. In nu/nu mouse xenografts, CCI-779 inhibited growth of MDA-MB-468 (sensitive) but not MDA-MB-435 resistant tumors. Treatment of sensitive lines with CCI-779 resulted in a decrease in D-type cyclin and c-myc levels and an increase in p27(kip-1) levels. There was good correlation between activation of the Akt pathway and sensitivity to CCI-779. Amplification of mTOR-regulated p70S6 kinase, which is downstream of Akt, may also have conferred CCI-779 sensitivity to MCF-7 cells. Taken together, the data suggest that mTOR may be a good target for breast cancer therapy, especially in tumors with Akt activation resulting from either growth factor dependency or loss of PTEN function.
Using genetic algorithm feature selection in neural classification systems for image pattern recognition

Pattern recognition performance depends on variations during extraction, selection and classification stages. This paper presents an approach to feature selection by using genetic algorithms with regard to digital image recognition and quality control. Error rate and kappa coefficient were used for evaluating the genetic algorithm approach Neural networks were used for classification, involving the features selected by the genetic algorithms. The neural network approach was compared to a K-nearest neighbor classifier. The proposed approach performed better than the other methods.
Effects of Dispersal for a Logistic Growth Population in Random Environments

We study a stochastic logistic model with diffusion between two patches in this paper. Using the definition of stationary distribution, we discuss the effect of dispersal in detail. If the species are able to have nontrivial stationary distributions when the patches are isolated, then they continue to do so for small diffusion rates. In addition, we use some examples and numerical experiments to reflect that diffusions are capable of both stabilizing and destabilizing a given ecosystem.
Analytical solution of air-gap field in motors with parallel magnetized permanent magnets

Analysis of airgap magnetic field is the basis of design and performance analysis of permanent magnet (PM) motors. Based on 2D models in polar coordinates, the analytical formulas of the open-circuit airgap flux density in PM motors equipped with parallel magnetised magnets are derived by solving the Laplace's equation or Poisson's equation in the regions of airgap, PM and shaft core. And based on the rotor with surface-mounted magnets, analytical formulas of rotors with cylindrical or ring-type PMs generally for high-speed PM motors are also obtained by mathematical methods. Considering the slotting effects, the calculation results of magnetic field analysis are modified by 2D relative permeance function. By comparing with finite element analysis, it is proved that this analytical method is correct and reliable because of their good agreement in waveform and magnitude. It provides a powerful tool for optimal design and performance analysis of PM motors.
Do patients with pressure ulcers benefit from oral zinc supplementation?

Role of Zinc Zinc is a trace mineral that is present in the body in small quantities in the bone, skin, and muscles. It is also an integral part of many enzymes, including the enzyme carbon anhydrase found in red blood cells, the gastrointestinal mucosa, the tubules of the kidney, and the epithelial cells of many glands. Zinc is a cofactor for protein synthesis and is transported by the protein albumin. In addition, it is a component of the peptidases that are responsible for digesting proteins in the gastrointestinal tract. Zinc plays an important role in the synthesis of deoxyribonucleic acid and ribonucleic acid, which foster tissue growth and healing and collagen synthesis. An adequate zinc level maintains the body_s sense of taste and smell and its immune function, which is important in the wound healing process. Zinc also assists in transporting vitamin A from the liver.
Photon distributions for nonclassical fields with coherent components.

Nonclassical fields with coherent components generated in a large number of optical processes including losses can be characterized by a Gaussian Wigner function centered around the mean value of the field. The photon-number distributions for such fields are calculated and the numerical results are presented for a range of parameters. As a special case we give the number distributions for photons produced in down-conversion problems. We also give the analytical expression for the photoelectron distributions.
Investigating institutional structures: a role-based design game as a source of innovations

Information system development (ISD) methodologies are generally lacking in serious attention to human activity. They focus more on implementation of a software product than on the development of the activity itself. In this paper the theoretical foundations for a new developmental method, a design game, are introduced. The approach is based on a research tradition which has been focusing on the representation and evaluation of ISs in use. The game will integrate the representation and analysis of existing division of labour into the reconstruction of it. Furthermore, the division of labour which is realised at the level of society can also be realised at the surface.
Transforming growth factor‐β and psoriasis: a new link

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Acute antigen-induced elevation of serum colony stimulating factor (CFS) levels.

Injection of endotoxin or Salmonella flagellins to C57BL mice caused 50–100-fold elevations, maximal at 3–9 hours, in the capacity of the serum to stimulate granulocyte and macrophage colony formation by mouse bone marrow cells in agar cultures. This response was not elicited by a variety of foreign serum proteins. The response was radioresistant but preimmunized mice showed a specific depression of responsiveness on challenge with the same antigen.