Miracle-dz/UniFAR-FTUs huggingface dataset:
Étude REAGE : construction d’un modèle pronostique dynamique du devenir hospitalier des patients âgés de plus de 80 ans en admission non programmée en réanimation

La reanimation d’attente vise a eviter la perte de chance et l’obstination deraisonnable en tentant d’etablir precocement le pronostic pour decider du niveau d’engagement. Elle constitue une reponse a l’augmentation des admissions des sujets âgees (SA) en reanimation. Notre etude retrospective au CHU de Grenoble a inclus les SA de 80 ans et plus en admission non programmee en reanimation afin de construire un modele pronostique evolutif aidant a la decision. Le devenir de 197 SA a ete analyse, 106 etaient encore en reanimation apres trois jours (J3). Ils avaient en moyenne 84 ans, un IGS II a 56,7, un SOFA initial a 6,7 et 67% venaient pour defaillance hemodynamique. Le premier jour (J1), 76% recevaient un support ventilatoire, 75% des amines et 13% une epuration extra-renale. Une limitation ou un arret therapeutique de J1 a J3, l’IGS II, le nombre d’organes defaillants a J3, le nombre de suppleances d’organe a J1 et J3, les evolutions du SOFA total et du nombre de suppleance de J1 a J3 etaient associes (p<0,05) au deces intra-hospitalier. Trois modeles pronostiques dynamiques du devenir hospitalier incluant differents aspects de la defaillance d’organe initiale et son evolution a J3 (SOFA, nombre d’organe defaillant et nombre de suppleance d’organe) ont ete realises. Les bien-classes atteignent 70%, l’aire sous la courbe ROC 0,77. Le niveau initial de defaillance d’organe et son evolution sous traitement apres trois jours sont fortement associes au pronostic hospitalier. L’integration de la fragilite, d’une comorbidite au stade terminal et du caractere reversible de la pathologie aigue pourrait ameliorer nos modeles. L’estimation de la qualite de vie reste a etablir.
Effects of Implant Microtopography on Osteoblast Cell Attachment

PurposeThe overall aim of this project was to study osteoblast cell attachment on titanium surfaces with varying surface roughness. Materials and MethodsCommercially pure titanium surfaces were prepared by polishing through 600-grit sandpaper, sandblasting, or sandblasting followed by acid etching to produce surfaces of varying roughness, as determined by scanning electron microscopy and atomic force microscopy. In vitro cell attachment of MC3T3-E1 osteoblasts was performed on the prepared surfaces in both serum-containing and serum-free media conditions. ResultsCell attachment was directly related to the average surface roughness, with the highest levels of cell attachment observed on sandblasted and sandblasted-acid-etched surfaces. Similar patterns of cell attachment were observed when serum-free conditions were employed. ConclusionsCombined surface analytical and cell/molecular biological techniques are powerful tools to broaden our understanding of biological events occurring at the implant-tissue interface. Data acquired from these in vitro techniques provide a translational application to in vivo clinical models leading to the next generation of dental implants.
Rethinking Breast Self-Examinations: Are We Asking the Right Questions?

There are a myriad of studies on the efficacy of BSE, with mixed results. Research also highlights growing health disparities and continuing limited access to technology in underserved communities. Results from a pilot study with rural teens suggest that successful skill mastery and sustained practice can be learned. Perhaps most importantly, BSE offers a technology-free method for self-assessment that can be taught at the community level and provides an opportunity for women to gain a measure of self-control over their bodies and themselves.
Angiogenic Activity as a Marker of Neoplastic and Preneoplastic Lesions of the Human Bladder

Angiogenic activity has been assessed in biopsy specimens from 49 patients with transitional cell carcinoma, benign prostatic hypertrophy and vesicoureteral reflux. Over 95% of the specimens containing malignant and premalignant transitional epithelium stimulated capillary proliferation on rabbit iris. In contrast, less than 10% of normal tissues had this effect. Sixty-one per cent of specimens with inflammatory round cells were angiogenic but this was reduced to 10% by preincubation with rabbit antihuman lymphocyte serum. Cystitis cystica also induced capillary proliferation even if incubated with the antilymphocyte serum. Angiogenic capacity may be an early marker of preneoplastic and neoplastic lesions of the human bladder.
Effect of Dietary Plant Lipids on Conjugated Linoleic Acid (CLA) Concentrations in Beef and Lamb Meats

Beef and lamb, are a food category with positive and negative nutritional attributes. Rumi‐ nant meats are major sources for many bioactive compounds including iron, zinc and B vita‐ mins. However they are associated with nutrients and nutritional profiles that are considered negative including high levels of saturated fatty acids (SFA) and cholesterol. It is well know that the low PUFA/SFA and high n-6/n-3 ratio of meats contribute to the imbal‐ ance in the in the fatty acid intake of today consumers [1]. Consumers are becoming more aware of the relationships between diet and health and this has increased consumer interest in the nutritional value of foods. Nutritionist advisers recommended a higher intake of poly‐ unsaturated fatty acids (PUFA), especially n-3 PUFA at the expense of n-6 PUFA.
Four cases of exogenous acral pigmentation related to a darkling beetle (coleoptera: tenebrionidae: blaps)

Editor Beetle (coleoptera) is the largest insect order colonizing all continents. Most of the beetles synthesize hemolymph containing several chemicals used as signals or defensive secretions against predators. Coleoptera body fluids can accidentally come into contact with humans’ skin and induce dermatitis. Skin contact with the beetles commonly causes blistering skin eruption. However, not all beetles secrete chemicals with vesicant proprieties. Accidental friction of a darkling beetle over the skin provoked an unusual pigmentation in four patients in our department. Four patients aged, respectively, 4, 15, 35 and 42 years visited us for an outbreak of a similar acral pigmentation. Physical examination revealed in all cases asymptomatic single or multiple pigmented macules of various shapes surrounded by a dark red or brown halo that fades gradually, located on the foot toe or the plantar region (Fig. 1a,b,c,d,e). There was no other skin or systemic anomaly. An accurate medical history revealed in all patients that it had a very sudden onset after crushing a ‘black beetle’, while putting their shoes in three cases and when walking barefoot in one case. The crushed arthropod was identified (Fig. 1f). Neither washing the lesion in water nor in antiseptics removed it. Dermoscopy showed a parallel-ridge pattern with brown pigmented parallel bands localized along skin ridges with lighter margins (Fig. 2a,b). In the histological study, the epidermis, dermis, and hypodermis were intact. A deposit of an exogenous pigment was visualized in the epidermis (Fig. 2c,d). These findings thereby made contact dermatitis due to epidermal migration of a pigmented fluid likely. The patients were reassured. The monitoring of the lesions was decided. The pigmentation faded spontaneously within 2–4 weeks in all cases with a complete resolution. No relapse was noticed several months after. In this report, a series of four cases of a distinct acute pigmented dermatitis after stepping on a beetle is presented. We conducted an entomologic study of the coleoptera associated with these lesions, which concluded to a blaps. Blaps genus belongs to the insect order coleoptera (beetles), superfamily tenebrionoidae, family tenebrionidae (darkling beetle),
An Enhanced Temporal Feature Integration Method for Environmental Sound Recognition

Temporal feature integration refers to a set of strategies attempting to capture the information conveyed in the temporal evolution of the signal. It has been extensively applied in the context of semantic audio showing performance improvements against the standard frame-based audio classification methods. This paper investigates the potential of an enhanced temporal feature integration method to classify environmental sounds. The proposed method utilizes newly introduced integration functions that capture the texture window shape in combination with standard functions like mean and standard deviation in a classification scheme of 10 environmental sound classes. The results obtained from three classification algorithms exhibit an increase in recognition accuracy against a standard temporal integration with simple statistics, which reveals the discriminative ability of the new metrics.
An improved design approach for LC tank VCOs

Fully integrated LC tank oscillators are widely used because they are able to fulfil the increasing requirements in the field of RF applications. In this paper formulas for investigations of the stability as well as the amplitude of CMOS LC tank oscillators are derived, where an overall model of nonlinear gain elements is used. By means of these results we are able to present an improved design approach which gives a deeper insight into the functionality of LC tank VCOs
Algorithms for harvested energy prediction in batteryless wireless sensor networks

Several wireless sensor network (WSN) applications leverage energy harvesting technologies such as small size photo-voltaic modules. The advantage of solar energy over other forms of environmental energy is that the available solar power can be predicted with reasonable accuracy allowing the implementation of efficient power management techniques. However accurate predictions of future energy profiles can be expensive in term of memory occupancy and complexity and a trade-off between accuracy and computational effort must be evaluated. In this paper we compare different solar energy prediction algorithms that give estimates future available energy over the time. They are computationally simple and have a small memory footprint to facilitate the implementation in resource limited solar harvesting sensor nodes. Simulation results show that the most effective predictors is possible achieve high accuracy, diverging from real energy profile by less than 10%.
LONGITUDINAL TRACKING OF MUSCULAR POWER CHANGES OF NCAA DIVISION I COLLEGIATE WOMEN GYMNASTS

Gymnastics relies upon power as a critical component of sports-specific fitness. The purpose of this study was to monitor long-term training adaptations in the power of National Collegiate Athletics Association Division I women gymnasts. Twenty members of a women's gymnastic team (aged 18–22) were tracked over 3 years with the first year a baseline year of testing. Whole body power for the counter-movement (CMJ) and squat (SJ) vertical jump was obtained via force plate analyses at 2 assessment time points during each year (February and November). Results showed significant (p > 0.05) and continued increases in peak power output in the CMJ and SJ at each biannual assessment. Improvements of 46% ( + 1010 W) for the CMJ and 43% ( + 900 W) for the SJ were observed at the end of the tracking period. Peak power for the CMJ and SJ were recorded at 3210 W (±350 W) and 3000 W (±152 W), respectively. Associated improvements in the time to peak power of 36% (-0.239 second) and 38% (-0.151 second) were also found for the CMJ and SJ. There were no significant changes in body mass or total skinfold thickness, however, a shift toward improved fat free mass (i.e., lean muscle mass) was apparent. These data underscore the importance that specificity, and more importantly power development, should play in the conditioning of collegiate women gymnasts' training programs.
Expression of the CD117 antigen (C‐Kit) on normal and myelomatous plasma cells

Summary. The surface expression of CD117 on plasma cells (PCs) from normal individuals and patients with multiple myeloma (MM) has been analysed using triple‐stained cells for flow cytometry. In addition, the clinical significance of CD117 expression in MM patients and its possible value for the evaluation of minimal residual disease was explored. A total of 11 healthy volunteers and 56 untreated MM patients were included in the study. The expression of CD117 was analysed by flow cytometry, using simultaneous staining with the MAbs BB4, CD117 and CD38. Cell acquisition was performed in two consecutive steps using a live gate drawn on SSC/CD38+++ cells and a total of 300000 events were acquired. For data analysis, the Paint‐a‐Gate Plus software (Becton Dickinson) was used. PCs were identified according to their strong reactivity for CD38 and their positivity for BB4, as well as by their light scatter distribution. Dilution experiments of CD117+ myelomatous PCs with normal bone marrow (BM) cells were performed in order to assess the sensitivity level of the technique for detection of CD117+ residual PCs. None of the PCs from normal BM samples showed reactivity for the CD117 antigen. In contrast, CD117 antigen was present in 18/56 MM patients (32%), the proportion of positive cells in these cases being as high as 92·1 ± 9%. Therefore, within PC lineage the c‐Kit antigen would be restricted to the myelomatous population and thus could be considered as a “tumour‐associated marker” for monitoring minimal residual disease in about one third of MM patients. Dilution experiments indicate that the detection limit with this marker would be 10−4 (one myelomatous PC/104 normal BM cells). Upon comparing the clinical and haematological disease characteristics of CD117‐positive and CD117‐negative cases, no significant differences were found.
Native Language Detection Using the I-Vector Framework

Native-language identification is the task of determining a speaker’s native language based only on their speeches in a second language. In this paper we propose the use of the wellknown i-vector representation of the speech signal to detect the native language of an English speaker. The i-vector representation has shown an excellent performance on the quite similar task of distinguishing between different languages. We have evaluated different ways to extract i-vectors in order to adapt them to the specificities of the native language detection task. The experimental results on the 2016 ComParE Native language sub-challenge test set have shown that the proposed system based on a conventional i-vector extractor outperforms the baseline system with a 42% relative improvement.
Pulmonary and Systemic Hemodynamic Responses to Fentanyl in Infants

Pulmonary and systemic hemodynamic responses to fentanyl were studied in 12 infants after repair of congenital heart defects. During controlled ventilation, hemodynamic responses to 25 μg/kg of fentanyl were measured. No significant changes were found in heart rate, cardiac index, mean pulmonary artery pressure, or pulmonary vascular resistance index 5 min after the fentanyl had been given. There were small but statistically significant decreases in mean arterial pressure and systemic vascular resistance index after fentanyl. We conclude that under the conditions of this study, pulmonary and systemic hemodynamics in infants are minimally altered by 25 μg/kg of fentanyl.
Phyllis Braudy Harris (Ed.). The Person with Alzheimer Disease: Pathways to Understanding the Experience. Baltimore, MD: The Johns Hopkins University Press, 2002.

RÉSUMÉ Il est grand temps, essentiel en fait, que nous accordions toute l'importance qu'il mérite au témoignage des personnes atteintes de démence. Cet ouvrage, s'appuyant sur le point de vue des personnes qui vivent avec la maladie, vient enrichir la masse croissante de connaissances sur la démence. Pour répondre à la question « Comment vit-on chaque jour avec une maladie mentale comme la maladie d'Alzheimer (MA)? », l'auteure choisit de donner la parole à des personnes atteintes de démence. L'ouvrage reconnaît la contribution de ces personnes au corpus de connaissances sur la démence, il relate leur expérience et dénonce les stigmates associés à la maladie: à savoir que ces personnes sont des coquilles vides qui représentent un fardeau pour la société. Au contraire, nous dit l'auteure, ce sont elles les « vrais experts », et nous devons les écouter. Cet ouvrage est un outil indispensable pour tous les fournisseurs de services de santé et ceux qui s'occupent de personnes atteintes de démence, mais aussi pour les enseignants, les chercheurs, les décideurs et le personnel des sociétés d'Alzheimer. Ceux qui vivent avec la démence auront le sentiment d'être compris en lisant le récit d'autres personnes dans leur situation. L'ouvrage apporte une contribution précieuse à la recherche sur la démence, il nous fait mieux comprendre la maladie du point de vue des « experts » – ceux qui vivent avec la démence.
Motivating parents to prevent caries in their young children: one-year findings.

BACKGROUND The authors conducted a study to compare the effect of a motivational interviewing counseling treatment with that of traditional health education on parents of young children at high risk of developing dental caries. OVERVIEW The authors enrolled in the study parents of 240 infants aged 6 to 18 months and randomly assigned them to either a motivational interviewing, or MI, group or a traditional health education (control) group. Parents in the control group received a pamphlet and watched a video. Parents in the MI group also received the pamphlet and watched the video; in addition, they received a personalized MI counseling session and six follow-up telephone calls. RESULTS After one year, children in the MI group had . 71 new carious lesions (standard deviation, or SD, = 2.8), while those in the control group had 1.91 (SD = 4.8) new carious lesions (t[238] = 2.37, one-tailed, P < .01). CONCLUSIONS MI is a promising approach that should receive further attention. CLINICAL IMPLICATIONS MI may lead parents and others to better accept dental recommendations about preventing caries in their children.
Weight and welfare of Australians, 1890-1940.

Views differ on whether living standards in Australia improved between 1890 and 1940. The pessimists, relying principally on product and incomes measures, argue that living standards stagnated; the optimists, using augmented measures of well-being, argue that living standards may have improved. This paper contributes to this debate between the pessimists and optimists by using alternative measures of living standards, namely the height and body mass index (BMI) of male Australian army recruits of World Wars I and II. The nature and usefulness of these measures is examined. The major findings are that the height data indicate an unequivocal improvement in living standards in the period under consideration. The BMI data tend to support a similar conclusion, but the results are ambiguous and there are difficulties in using them alone to determine exactly what happened to living standards.
Encryption with weakly random keys using a quantum ciphertext

The lack of perfect randomness can cause significant problems in securing communication between two parties. McInnes and Pinkas [13] proved that unconditionally secure encryption is impossible when the key is sampled from a weak random source. The adversary can always gain some information about the plaintext, regardless of the cryptosystem design. Most notably, the adversary can obtain full information about the plaintext if he has access to just two bits of information about the source (irrespective on length of the key). In this paper we show that for every weak random source there is a cryptosystem with a classical plaintext, a classical key, and a quantum ciphertext that bounds the adversary's probability p to guess correctly the plaintext strictly under the McInnes-Pinkas bound, except for a single case, where it coincides with the bound. In addition, regardless of the source of randomness, the adversary's probability p is strictly smaller than 1 as long as there is some uncertainty in the key (Shannon/min-entropy is non-zero). These results are another demonstration that quantum information processing can solve cryptographic tasks with strictly higher security than classical information processing.
Intrauterine growth restriction in neonatal piglets affects small intestinal mucosal permeability and mRNA expression of redox‐sensitive genes

Neonates with intrauterine growth restriction (IUGR) show lower efficiency of nutrient utilization compared to normal birth weight (NBW) newborns. This study was conducted using neonatal piglets as a model to test the hypothesis that IUGR affects the intestinal barrier function, intestinal structure, and antioxidant system development during the suckling period. The small intestinal mucosae were obtained from IUGR and NBW littermates in the suckling period (d 0, 3, 8, and 19 postnatal). The epithelial barrier function was assessed by FITC‐dextran 4 (FD4) and horseradish peroxidase (HRP) fluxes across the epithelium, histomorphologic measurements, and expression of tight‐junction proteins. Redox status represented by the glutathione disulfide/glutathione ratio and malondialdehyde concentrations was determined, whereas mRNA expressions of some redox‐sensitive proteins were quantified. Results showed that IUGR piglets exhibited a 2‐fold higher intestinal permeability in the proximal small intestine on d 0 (P < 0.05), and this difference between IUGR and NBW piglets was widened to 3 and 4 times for FD4 and HRP, respectively (P< 0.05), on d 3. In accordance, expression of occludin was downregulated at the transcriptional level in IUGR piglets at d 0 and 19 (P < 0.01). Furthermore, the transcription of heme oxygenase 1, catalase, and thioredoxin reductase genes was downregulated in IUGR piglets, mainly on postnatal d 0 and 19 (P < 0.01). It appears that IUGR subjects have a lower capacity to mount an antioxidant response in the early postnatal period. Collectively, these results add to our understanding of the mechanisms responsible for intestinal dysfunction in IUGR neonates. —Wang, W. , Degroote, J., Van Ginneken, C. , Van Poucke, M. , Vergauwen, H. , Dam, T. M. T. , Vanrompay, D. , Peelman, L. J., De Smet, S. , Michiels, J. Intrauterine growth restriction in neonatal piglets affects small intestinal mucosal permeability and mRNA expression of redox‐sensitive genes. FASEB J. 30, 863–873 (2016). www.fasebj. org
L’arganeraie marocaine, un système traditionnel face aux mutations récentes : le cas du territoire des Haha, Haut Atlas occidental

L’arganeraie est un ecosysteme d’une grande importance ecologique, culturelle et economique. Son modele socio-economique est reste traditionnel, organise d’une part autour d’une structure socio-juridique particuliere et qui fonctionne d’autre part sur la base de productions variees. L’huile d’argane est la production la plus notoire de l’arganeraie des Haha, mais la croissance demographique, combinee aux conditions naturelles difficiles et a une exploitation superieure aux capacites de production, rend de plus en plus difficile l’application des regles traditionnelles de gestion durable. Cela implique des mutations socio-spatiales qui destabilisent un systeme fragile. L’arganeraie des Haha ; celebre confederation de tribus du Haut-Atlas occidental, en est l’exemple type.