Miracle-dz/UniFAR-FTUs huggingface dataset:
AMCIS 2017 Panel Report: Experiences in Online Education

In this AMCIS 2017 online education panel, five experienced business school professors from differently sized public and private institutions in three different countries (USA, Mexico, and Spain) discussed how online education (i.e., eLearning, technology-mediated knowledge transfer) occurred in their institutions. They presented low-budget and high-budget examples and described what they have found to be best practices in eLearning at both the institution and the instructor level. They also demonstrated that one can accomplish online education in many different ways and with varying budgets, but, as long as one bases it on solid educational principles and mastery of the technology, it can be as effective as (if not more than) traditional face-to-face education. This report builds on their presentations and additional information gathered from the literature.
A Demographic Perspective of Smartphone Security and Its Redesigned Notifications

: Billions of smartphones, globally, are running out-of-date Operating Systems (OS) which make them vulnerable to cyberattacks. Behaviours of users in updating their OS vary between di ﬀ erent geographic locations considering various demographic factors. For instance, developing countries have a very di ﬀ erent stance compared to developed ones on how their users perceive device updates. To assert our claim, we ﬁrst investigated security behaviours among di ﬀ erent demographics in Japan and Tanzania. The results indicate that demographic factors such as culture, income, and geographic location highly impact behaviours of participants on OS updating. However, education and awareness do not seem to have signiﬁcant impact on security behaviours. Consequently, insecure behaviours were equally exhibited among most participants regardless of their education levels or awareness. We also found that most participants do not update their application software on their smartphones despite being aware. Moreover, in the developing country settings, most participants tend to avoid certain security advice because they necessitate incurring data charges that take up a high percentage of their incomes. Then, we surveyed and evaluated the participants’ preferences for di ﬀ erent re-designed security notiﬁcations for improving update compliance. Finally, we propose color-coded fear-appeal designs for persuading users into updating their devices’ application software.
𝓁0 Regularized Structured Sparsity Convolutional Neural Networks

Deepening and widening convolutional neural networks (CNNs) significantly increases the number of trainable weight parameters by adding more convolutional layers and feature maps per layer, respectively. By imposing inter- and intra-group sparsity onto the weights of the layers during the training process, a compressed network can be obtained with accuracy comparable to a dense one. In this paper, we propose a new variant of sparse group lasso that blends the $\ell_0$ norm onto the individual weight parameters and the $\ell_{2,1}$ norm onto the output channels of a layer. To address the non-differentiability of the $\ell_0$ norm, we apply variable splitting resulting in an algorithm that consists of executing stochastic gradient descent followed by hard thresholding for each iteration. Numerical experiments are demonstrated on LeNet-5 and wide-residual-networks for MNIST and CIFAR 10/100, respectively. They showcase the effectiveness of our proposed method in attaining superior test accuracy with network sparsification on par with the current state of the art.
Efficacy and Toxicity of Pemetrexed or Gemcitabine plus Cisplatin in Treatment of Patients with Non-small Cell Lung Cancer

Objective To observe the efficacy and toxicity of pemetrexed or gemcitabine plus cisplatin in treatment of patients with non-small cell lung cancer(NSCLC). Methods 50 patients with late stage NSCLC were enrolled into this study.These patients were divided into PC(pemetrexed plus cisplatin) group (n=25) and GC (gemcitabine plus cisplatin)group (n=25) (PC: pemetrexed 500mg/m2 plus cisplatin 30mg/m2, GC:gemcitabine 1000mg/m2 plus cisplatin 30mg/m2). The efficacy of patients received two or more cycles will be evaluated.Results Altogether 50 patients were evaluated. The effective rate in PC groups was 48% and in GC group was 44%. The common side effects were gastrolntestinal toxins and hematologic toxicities including nausea, neutrocytopenia,and anemia, but they were rarer in PC group. Conclusions Pemetrexed plus cisplatin had the same activity as gemcitabine plus cisplatin in treatment of patients with NSCLC,and they appeared to be more-tolerated.
INCREASED RISK OF THROMBOEMBOLISM AS A RESULT OF HIGH THROMBIN PRODUCTION IS ASSOCIATED WITH SHORT ACTIVATED PARTIAL THROMBOPLASTIN TIME IN CANCER PATIENTS ON AND AFTER CHEMOTHERAPY: A PROSPECTIVE STUDY IN A TERTIARY CARE HOSPITAL

To investigate wheather cancer patients during and following chemotherapy with short activated partial thromboplastin times (aPTTs) have increased thrombin generation and are at increased risk for thromboembolism, this prospective study was designed. Routine coagulation specimens of such patients were screened for the presence of short or normal aPTT for 5-month period, and, accordingly, 250 specimens were collected. Prothrombin fragment F1+2 (F1+2) was measured to evaluate thrombin activation, and a second aPTT was performed with a different reagent. Clinical history were obtained from medical records after conclusion of sample collection. 6 to12months later, patients were questioned on thromboembolic events during the previous 18 months by questionnaire. F1+2 and the incidence of venous thromboses were elevated significantly in the short aPTT group. Patients with acute bleeding had short aPTTs, but 36% of these also had thromboembolic events during the 18 months proximal to blood collection. These findings were confirmed with the second aPTT reagent. Patients with short aPTTs have increased thrombin generation and are at increased risk for thromboembolism, mainly venous thromboses, despite the fact that a short aPTT can occur in the acute setting of bleeding. INTRODUCTION: The prothrombin time (PT) and the activated partial thromboplastin time (aPTT) are routine coagulation tests used to assess the coagulation system in a clinical setting. Numerous factor deficiencies are known to prolong the respective screening test result and can be related to bleeding; (1) however, prolongation of the aPTT may be related to a hypercoagulable state if a lupus anticoagulant is present. (2) A clinically relevant decrease in the activity of clotting factors usually related to the prolongation of one of the respective routine screening test results. By analogy, shortened clotting times could, therefore, be the expression of a hypercoagulable state. Earlier studies have found some evidence that short aPTTs are related to a higher incidence of throm- boembolic disorders. (3, 4) These findings have been disputed, and there is some suggestion in the literature that short aPTTs occur during bleeding episodes. (5, 6) Nowadays, molecular markers of activation processes in the coagulation and fibrinolytic system have become widely available for use in the specialized clinical laboratory. Prothrombin fragment F1+2 is cleaved from prothrombin on activation by factor Xa in amounts equimolar to the thrombin generated. (7) Consequently, F1+2 levels have been shown to reliably measure the amount of prothrombin activation and, thus, thrombin generation. (8) The purposes of the present study were to evaluate the hypothesis that in cancer patients
Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet

Background The effect of dietary composition on blood pressure is a subject of public health importance. We studied the effect of different levels of dietary sodium, in conjunction with the Dietary Approaches to Stop Hypertension (DASH) diet, which is rich in vegetables, fruits, and low-fat dairy products, in persons with and in those without hypertension. Methods A total of 412 participants were randomly assigned to eat either a control diet typical of intake in the United States or the DASH diet. Within the assigned diet, participants ate foods with high, intermediate, and low levels of sodium for 30 consecutive days each, in random order. Results Reducing the sodium intake from the high to the intermediate level reduced the systolic blood pressure by 2.1 mm Hg (P<0.001) during the control diet and by 1.3 mm Hg (P=0.03) during the DASH diet. Reducing the sodium intake from the intermediate to the low level caused additional reductions of 4.6 mm Hg during the control diet (P<0.001) and 1.7 mm Hg during t.
Clinical application of radiofrequency ablation technology

For recent two decades,radiofrequency ablation technology(RFA)has made great progress in the field of the treatment for diseases for its distinguishing characteristic of microtrauma,targeted,effective and almost having no side-effect.At the very beginning,radiofrequency ablation was adopted in treating solid tumors,and since then it has been gradually practiced in treating benign diseases of solid organs such as hypersplenism,prostatic hyperplasia and widely used in almost every system of the body.Here,we review its therapic principle,types and clinical application.
Percutaneous Ablation for Lung Tumors

Lung cancer remains the largest cause of cancer death worldwide. Surgical resection remains the best chance of cure, but only 20% of patients are eligible for this treatment. Traditionally, the remaining patients have been managed with combinations of radiotherapy and chemotherapy; however, outcomes have been poor. Recently, techniques such as stereotactic radiotherapy and thermal ablation have shown promise with outcomes rivalling surgery. This review discusses the principles, technique, outcomes, and complications of the 3 most utilized thermal ablative techniques (radiofrequency ablation, microwave ablation, and cryoablation) for lung tumors.
Effect of Polyherbal Formulation on Metabolic Derangements in Experimental Model of High Fructose Diet Induced Metabolic Syndrome.

High fructose diet induces metabolic syndrome. Therefore an attempt has made to evaluate the effect of Polyherbal formulation in male Wistar rats by oral administration of 350 mg/Kg body weight (HF1) and 500 mg/ Kg body weight (HF2). The clinical symptoms established in high fructose diet induced metabolic syndrome were ameliorated by Poly herbal formulation. Food, water intake was increased in high fructose diet fed rats. Body weight, abdominal waist and Body mass index were increased in only high fructose fed rats whereas reduced with poly herbal formulation. Atherogenic index and Blood pressure were increased in only high fructose fed rats but reduced in rats supplied with polyherbal formulation (HF1 and HF2) along high fructose. Biochemical components like fasting blood glucose levels, triglycerides, total cholesterol, LDL, VLDL, SGOT, SGPT, Uric acid, Malondialdehyde (MDA) were increased in only high fructose fed group rats whereas these components were reduced and normalised in groups of rats fed with high fructose diet for 7 weeks in association with Herbal formulation HF1, HF2 for last three weeks separately.HDL-C levels were found increased in rats even though supplied with polyherbal formulation. Histopathology results of pancreas and liverof only high fructose fed rats indicated the infiltration of inflammatory cells and fat accumulation which was ameliorated with HF1 and HF2.
MOUTH DISSOLVING TABLET: REVIEW

Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. Fast- or mouth dissolving tablets have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. Fast dissolving Tablets are disintegrating and/or dissolve rapidly in the saliva without the need for water. FDTs are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast-dissolving tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed fast-disintegrating tablets, as they may take up to a minute to completely disintegrate. This tablet format is designed to allow administration of an oral solid dose form in the absence of water or fluid intake. Such tablets readily dissolve or disintegrate in the saliva/ oral cavity within less than one minute (within <60 seconds) leaving an easy-toswallow residue. Such formulations provide an opportunity for product line extension in the Many elderly persons will have difficulties in taking conventional oral dosage forms (viz., solutions, suspensions, tablets, and capsules) because of hand tremors and dysphagia. Swallowing problems also are common in young individuals because of their underdeveloped muscular and nervous systems. Other groups that may experience problems using conventional oral dosage forms include the mentally ill, the developmentally disabled, and patients who are uncooperative, on reduced liquid-intake plans, or are nauseated. In some cases such as motion sickness, sudden episodes of allergic attack or coughing, and an unavailability of water, swallowing conventional tablets may be difficult.
Cerebral Palsy and Rehabilitation

Cerebral palsy (CP) is the most common cause of disability in early childhood. It may present with delay in milestones such as head holding, sitting or walking; muscle tone abnormalities or balance and gait disorders. Epilepsy, mental retardation, speech disorders, strabismus and visual disturbances may accompany these motor disorders. In CP rehabilitation, the main objective is to keep the functional status at the optimal level, to prevent the secondary disorders and to improve the quality of life of the patient. For this reason, CP patients should be monitored by a rehabilitation physician regularly and the treatment must be redirected according to the encountered problems.
Hypoxia During Thoracic Surgery: Practical Advice for the Anesthesiologist

Double-lumen tubes or bronchial blockers are used to provide one-lung ventilation (OLV) in patients undergoing lung, esophageal, thoracic vascular, minimally invasive cardiac, and occasionally mediastinal surgery. During OLV, an intrapulmonary shunt may result in hypoxemia related in part to collapse of the nondependent lung and increased atelectatic areas in the dependent lung. Hypoxemia by definition is a decrease in oxygen saturation (SpO2) to less than 90% 4 or an arterial oxygen tension (PaO2) of less than 60 mmHg when the patient is being ventilated at an inspired oxygen fraction (FiO2) of 1.0. 5 The incidence of hypoxemia during OLV has been reported to be 1 to 10%. This relative infrequency is related in part to advances with routine use of a fiberoptic bronchoscope for optimal placement of lung isolation devices. It is also attributable to the introduction of newer volatile anesthetics that cause less inhibition of hypoxic pulmonary vasoconstriction (HPV) in a dose-dependent manner and less venous admixture during OLV. This review focuses on the predictors of hypoxia during OLV, the pathophysiology of HPV, protective ventilation maneuvers to restore or improve arterial oxygenation, the effects of anesthetics on hypoxia and inflammation, and cerebral desaturation episodes and hypoxia during OLV.
RISK FACTORS OF POSTOPERATIVE PULMONARY COMPLICATIONS AFTER SURGERY FOR ESOPHAGEAL CANCER USING UNIVARIATE AND STEPWISE LOGISTIC REGRESSION ANALYSES

In order to clarify the predictive risk factors of postoperative pulmonary complications after surgery for esophageal cancer, 33 cases undergoing esophagectomy under thoracotomy were evaluated using univariate analysis and stepwise logistic regression analysis. In our department, postoperative pulmonary complications are defined as those demanding respiratory management for more than one week or those needing oxgen administration for more than 2 weeks. Postoperative pulmonary complications were observed in 9 cases (27.3%). With univariate analysis, FEV1.0/m2, MVV/m2 and bledding volume during surgery were significantly different between the cases with and without pulmonary complications, with stepwise logistic regression analysis, FEV1.0/m2, bleeding volume during surgery and duration of thoracotomy were selected as predictive factors of pulmonary complications. Risk score=0.742+0.0001517×bleeding volume during surgery+0.002655×duration of thoracotomy-0.796×FEV1.0/m2 was obtained by multivariate statistical analysis. Significantly high incidence of pulmonary complications was observed in patients with risk socre more than 0.36, These results suggested that to prevent postoperative pulmonary complications, over surgery should be avoided especially in the patients with obstructive pulmonary dysfunction.
Review of "Connecting to the net.generation: What higher education professionals need to know about today's students"

For those of us college administrators who came of age in that (not so) long-ago era before the Internet, and who (perhaps) are still struggling to master web browsing and even email, dealing with computer technologies and the issues they raise can seem an almost hopelessly daunting task. This is not to say that we (necessarily) are “old fogeys. ” Given the extraordinary speed of Internet developments, even people who have not yet reached the untrustworthy age of 30 can count themselves among this group. As one court aptly put it, “in the Internet environment,” a single year is the equivalent of “several generations, if not an eternity” (Earthweb, 1999). Seemingly every week brings with it the announcement of some new such technology that is both child’s play and irresistibly tempting to our students, but mind-numbingly confusing to the rest of us: blogs; wikis; social networking sites; virtual worlds; yet another variation on file sharing; or some other equally bewildering, and frequently even unpronounceable, gizmo or doohickey.
Assessment of TB Stigma among Patients Attending Chest Hospital in Suez Canal University Area , Egypt

Background: TB stigmatization is a complex process involving institutions, communities, and interand intra-personal attitudes. While it has been recognized as an important social determinant of health and health disparities, the difficulties in identifying, characterizing, measuring, and tracking changes in stigmatization over time have made it challenging to justify devoting resource intensive interventions to the problem. Objectives: To identify the magnitude and the burden of TB stigma on patient and effect of TB stigma on treatment adherence. Methods: The data were collected between August and December 2014, recruiting all patients who had commenced treatment for up to a month. All patients were subjected to personal detailed interview according to a predesigned questionnaire after taking informed consent of the patients. Results: A total of 53 patients consented to participate. The mean age ± SD was 43 ± 14.1 years. Out of the total number, 22.6% were illiterate and 77.4% were literate. As regards occupation, 69.8% were independent and 30.2% were dependent. The stigma prevalence among TB patients was found to be 41.5%. Stigma is more prevalent among the younger age group (43.5 %), males (43.9 %) and among married patients (46.7%). There was an immense stigma observed among urban residence (57.7 %), current smokers (60.0 %) and those who had two or less rooms in their house (66.7 %) and this was found to have a statistically significant difference (P<0.05). The majority of patients (67.9%) take treatment regularly. Conclusion: TB stigma has been raised as a potential barrier to home and work-based direct observational therapy (DOT). Perceived TB stigma had no effect on treatment regularity. Health education programs should be conducted to reduce TB stigma and improve patients’ compliance.
Biologics in Staphylococcus aureus arthritis

The emergence of new type of drugs known as biologics has led to rapid disease improvements in many autoimmune arthritic patients. Nevertheless, most of these biologics are immunomodulators that may consequently increase the susceptibility of patients towards infections, such as septic arthritis. Septic arthritis is still considered a major public health challenge due to its rapidly progressive disease character with poor prognosis regarding joint functions. It is mainly caused by Staphylococcus aureus and despite optimal antibiotic treatment, nearly half of patients have permanent joint dysfunction. The main aim of this thesis was to investigate the inflammatory response of the host to living as well as antibiotics-killed S. aureus and to study the effect of biologics on the course of staphylococcal infections. The role of host inflammatory response on post-infectious joint dysfunction using antibiotickilled S. aureus was the subject of Paper I of this thesis. The main focus of Paper II and III were to study the effects of different biologics treatments on S. aureus induced septic arthritis and sepsis. We demonstrated that antibiotic-killed S. aureus is capable of inducing and maintaining destructive arthritis. By using different knockout mice, we showed that this type of arthritis was mediated through TLR-2, TNFR1 and RAGE receptors. Furthermore, we found that insoluble cell debris was a key initiator of this type of arthritis. Finally, anti-TNF therapy attenuated the arthritis caused by antibiotic-killed S. aureus. All the biologic treatments tested (including anti-TNF therapy, CTLA4-Ig and IL-1 Ra) aggravated S. aureus infections but had different clinical manifestations. Both CTLA4-Ig and IL-1 Ra therapy significantly increased the susceptibility to S. aureus induced septic arthritis in mice. Anti-TNF therapy on the other hand resulted in more severe weight loss and impaired the bacterial clearance ability of the host. In conclusion, antibiotic-killed S. aureus induced chronic destructive arthritis and anti-TNF therapy attenuated this type of joint inflammation. In the living S. aureus induced septic arthritis, all tested biologics complicated the disease course. Therefore, the potential dangers associated with biologics should be taken into account and patients with high risk of S. aureus bacteremia might be considered to refrain from them.