Miracle-dz/UniFAR-FTUs huggingface dataset:
Factorización de N: recuperación de factores primos a partir de las claves pública y privada

Se puede factorizar N y hallar sus factores primos a partir del conocimiento de la clave pública e y la clave privada d en un criptosistema RSA. Se analiza y resuelve el problema en forma matemática y luego se muestra un algoritmo para su implementación computacional. La aritmética de punto flotante no aporta la exactitud necesaria para las actuales longitudes de las claves. Luego el algoritmo presentado prescinde de ella, utilizando el método de Newton-Raphson para hallar uno de los factores. Se podrá así analizar la solidez de su esquema RSA y cambiarlo en caso de considerarse que no es lo suficientemente seguro.
Differential control of the inspiratory intercostal muscles during airway occlusion in the dog.

1. The effect of airway occlusion on the electrical activity of the three groups of inspiratory intercostal muscles (external intercostal, levator costae, parasternal intercostal) situated in the cranial portion of the rib‐cage has been studied in thirty anaesthetized, spontaneously breathing dogs. 2. The three muscles were active during normal inspiration, and their activity was prolonged similarly during airway occlusion. However, a comparison of activity during occluded and unoccluded inspirations indicated that airway occlusion caused a facilitation of external intercostal and levator costae activities but an inhibition of parasternal intercostal activity. 3. The facilitation of external intercostal and levator costae activities was markedly reduced after section of the phrenic nerves and completely suppressed after section of the appropriate thoracic dorsal roots. 4. The inhibition of parasternal intercostal activity was not affected by section of the phrenic nerves or by section of the thoracic dorsal roots. This phenomenon, however, was abolished after bilateral cervical vagotomy. 5. Activation of the external intercostals and levator costae during inspiratory efforts are thus highly dependent on segmental reflexes arising in these muscles. In contrast, activation of the parasternal intercostals resembles that of the diaphragm in the sense that it depends primarily on the central respiratory drive.
Computergraphik in der craniofacialen Chirurgieplanung

Dipl. -Ing. Envin Keeve studierte von 1986-1991 an der Universität Siegen Elektrotechnik mit den Schwerpunkten Regelungstechnik und Nachrichtentechnik. Von 1991 bis 1993 war er wissenschaftlicher Mitarbeiter in der Arbeitsgruppe Computergraphik / Computeranimation der Kunsthochschule für Medien Köln und arbeitet seit dieser Zeit im Bereich Computer-Aided Surgery. 1993 wechselte er als wissenschaftlicher Mitarbeiter an den Lehrstuhl für Nachrichtentechnik der Friedrich-Alexander-Universität Erlangen-Nümberg. Dort arbeitet er als Doktorand in der Arbeitsgruppe Bildkommunikation weiterhin in dem oben genannten Bereich. Seine Forschungsinteressen gelten hauptsächlich den Bereichen Computer Graphics and Animation, Human Facial Modeling, Computer-Aided Surgery und Interactive Media.
Design of the monitoring and analysis system of the Internet Education Public Sentiment

The Internet already became the main carrier of reflecting the educational information. The Internet Education Public Sentiment forms rapidly, greatly affects the society, it has already caused the close attention of the government and the related educational departments. It is necessary to design and develop a monitoring and analysis system of the Internet Education Public Sentiment for education. This paper analyzed and designed the basic function of the system, and designed the overall framework and the workflow chart of the system, then introduced the key modules' work mechanism of the system in detail.
Glucan-binding factor in saliva

High-molecular-weight polymers of alpha-1,6-linked D-glucans are insoluble in alcohol solutions. Whole, but not parotid, saliva prevented the precipitation of D-glucans by 80% (vol/vol) ethanol, showing that the whole saliva contained a factor which complexed with the glucan to render it alcohol soluble. The glucan-binding factor was retained on a column of Sephacryl S-200 which had been preequilibrated with 80% ethanol. The factor was then eluted with water. Passive hemagglutination assays revealed that the glucan-binding factor could sensitize erythrocytes to agglutination with anti-poly(glycerolphosphate), suggesting that the active glucan-binding component with lipoteichoic acid. The glucan-solubilizing factor was resistant to heat (100 degrees C), proteases, sialidase, lysozyme, lactoperoxidase, trichloroacetic acid, and Triton X-100. When sucrose was added to saliva, a suspension of Streptococcus cricetus AHT, or a suspension of Streptococcus sanguis 10556, relatively large amounts of glucan-binding factor were released in a soluble form. In addition, penicillin G caused the release of the glucan-solubilizing component from a suspension of S. cricetus AHT. It is suggested that whole saliva contains a component, tentatively identified as lipoteichoic acid, which can complex with glucans in a relatively hydrophobic solvent. This type of complex formation may be important in the adhesion of oral streptococci to saliva-coated surfaces.
Competencia de intermediarios financieros en Perú

Estimamos el indicador de competencia H de Panzar y Rosse (1987) en la industria bancaria en el Peru para el periodo enero de 2001 hasta diciembre de 2013. Encontramos que este indice se encuentra alrededor de 0.5, consistente con una estructura de mercado de competencia monopolistica. No obstante, en los ultimos anos el comportamiento de H sugiere que la competencia en la industria bancaria en el Peru habria crecido. Estos resultados estan en linea con la trayectoria creciente del numero de bancos y la reduccion del margen de intermediacion promedio durante el periodo en consideracion. Extendemos el analisis a la industria de las cajas municipales y encontramos que el grado de competencia es mayor que en la industria bancaria. Asimismo, el indicador de competencia tiene una tendencia creciente desde inicios de la muestra, aunque se habria estabilizado en los ultimos anos. Este resultado esta en linea con la trayectoria del margen de intermediacion y no guarda relacion con el numero de competidores.
APORTACIONES AL USO DE LA BELLOTA COMO RECURSO ALIMENTICIO POR LAS COMUNIDADES CAMPESINAS

La comunicacion que presentamos es un avance de un proyecto de investigacion, que se viene desarrollando desde hace unos anos en el marco de un convenio entre la Facultad de Humanidades y la Diputacion Provincial de Toledo, que pretende documentar los sistemas de aprovechamiento del encinar en el pasado por parte de grupos humanos, especialmente desde el punto de vista alimenticio.
GPUMF: A GPU-Enpowered Collaborative Filtering Algorithm through Matrix Factorization

Recommender system is a core component in many intelligent service systems. A good personalized recommender is an important service to users. Collaborative Filtering (CF), an effective approach to recommendation, has been widely used in many real-life systems. Matrix Factorization (MF) is an important approach to CF, because MF has flexibility in dealing with various data aspects and other application-specific requirements. However, the large computational burden required by MF poses a challenge of speeding up the MF process. In the past few years, Graphics Processing Unit (GPU) has evolved into a very flexible and powerful many-core processor. By transforming the traditional MF model, we can exploit the large-scale parallelization features of a massively multithreaded GPU. The results on various types of data show that the proposed algorithm can be well suited for the massively parallel GPU architecture.
Effects of the spatial repellent metofluthrin on landing rates of outdoor biting anophelines in Cambodia, Southeast Asia

The emergence of artemisinin‐resistant malaria in Southeast Asia is a major problem. The fact that many people become infected with malaria when they are outside has prompted the development of ‘spatial’ rather than topical repellents. The respective effects of one or four slow‐release emanators of metofluthrin, a pyrethroid, were tested in Pailin, Pursat and Koh Kong, Cambodia. Numbers of mosquitoes counted in outdoor landing catches when one or four emanators were suspended close to the collector were compared with control collections. In Pailin, the effects of emanators on catches in Furvela tent traps and Centers for Disease Control (CDC) light traps suspended underneath houses were also investigated. Rate ratios were used to determine differences. A total of 29 255 mosquitoes were collected over 2934 h of landing collections, 87 nights of tent trapping and 81 nights of light trap capture. In Pailin, landing rates were reduced by 48% by a single emanator and by 67% by four emanators (P < 0.001). Similar reductions were observed in the number of mosquitoes collected in tent traps and the number of anophelines only collected in light traps. Results were similar in Pursat, but, for unknown reasons, those in Koh Kong showed no difference between control and metofluthrin collections (P > 0.05). These findings suggest that although the product can produce a significant effect, it requires further improvement.
Kinematic analysis of an Underwater Parallel Robot

In this paper we present the kinematic analysis of an Underwater Parallel Robot, named Remo II. Due to its structure, this robot requires a smaller number of thrusters to navigate than other underwater vehicles. However, the kinematics of this robot is more complex than that of conventional underwater robots. The inverse position, velocity and acceleration kinematic analyzes of Remo II, are performed. This formulation is easily parallelizable and can be implemented in multiple-core processors.
Osteosarcoma

A trial of intravenous injections with BCG in dogs with osteosarcoma is now in progress (Owen & Bostock 1974). Following diagnosis the affected limb is amputated and I ampoule ofBCG (Glaxo, percutaneous) containing 50-250 x 106 living organisms injected intravenously. In some instances the vaccine has been mixed with heavily X-irradiated autologous osteosarcoma cells. Repeated intravenous injections with BCG alone are made at 1, 2, 4, 8, 8, and 8 weeks. Survival times have varied from 14 to 76 weeks, with 8 of 16 dogs which can so far be assessed surviving for more than a year. The majority of dogs have eventually developed metastases in the lungs. Toxic effects have usually not been serious and have included pyrexia, anorexia and in individual dogs glossitis and pharyngitis. Anaphylactic shock can be prevented by the prior administration of antihistamine drugs. The widespread granulomas which develop particularly in the lungs and liver appear to heal if sufficient time (probably at least three months) has elapsed from the last injection. The mechanism of death of tumour or inhibition of growth of micrometastases is not fully understood but it appears likely that the nonspecific destruction of tumour cells by macrophages activated by BCG plays a major role. It is planned to alternate this type of treatment with intermittent chemotherapy.
Synchronization of Electroencephalography and Eye Tracking using Global Illumination Changes

This paper describes a flexible method for synchronizing electroencephalography (EEG) and eye tracking (ET) recordings to the presentation of visual stimuli. The method consists of embedding a synchronization signal in the visual stimuli, and recording this signal with both the EEG and ET equipment. The signal is recorded by the EEG device as an additional data channel, and with the camera used in the ET equipment by modulating the global illumination of the scene in time with the synchronizing signal. The prototype system where this method was implemented resulted in a single sample of jitter in both the EEG and ET system, while the ET system achieved a spatial resolution of 1.26 degrees. The system will be used in future work with augmented memory applications.
Coming into the Country: Early Paleoindian Hunting and Mobility

Hunter-gatherer adaptations to long-term fluctuations in regional resource structure require mechanisms to cope with periodic subsistence stresses. Among documented groups, a common response to such stress is temporary movement into adjacent occupied areas-moving in with "relatives" when things go wrong. However, in the case of early (ca. 12,000-10,000 B.P.) Paleoindian groups in the Americas, the availability of neighboring groups with a detailed knowledge of local resource geography could not be relied upon. Post-Pleistocene environmental changes and the low initial population of the New World are important factors conditioning a lifeway characterized by a dependence on hunting (though not exclusively of megafauna), and by high residential, logistical, and range (territorial) mobility. Early Paleoindian groups had to adopt a subsistence technology that could be employed regardless of the specific resource microstructure. In some regards, Paleoindians seem to have behaved like tropical foragers while in others like arctic collectors. Use of high quality lithic raw materials from large quarry sources, reliance on a bifacial technology, limited use of caves and rockshelters, and a low level of processing of food products for storage all may be indicative of such a subsistence technology, which would have been unlike that of any modern hunter-gatherers.
ELECTROCHEMICAL EPITAXIAL GROWTH OF A PT(111) PHASE ON AN AU(111) ELECTRODE

The electrochemical deposition of platinum on an Au(111) single-crystal electrode in acidic solutions containing H2PtCl6 was studied using an electrochemical scanning tunneling microscope (STM) and electrochemical quartz crystal microbalance (EQCM). The STM investigation showed an ordered adlayer of PtCl62- on the electrode surface during the electrochemical deposition of platinum and a Pt(111)-(1×1) structure on the electrode surface after the electrode was rinsed with a Pt complex-free solution. Formations of the Pt(111) bulk phase and surface structure of Pt(111)-(1×1) were confirmed by X-ray diffraction (XRD) and the underpotential deposition of copper and hydrogen, respectively.
Smart optimal control of DVR to compensate voltage sag of the critical loads in the distribution power system

Voltage sag is one of the most severe power quality disturbances to be dealt with by the industrial sector, as it can cause severe process disruptions and results in substantial economic loss. This paper presents an optimal method of control for the low voltage dynamic voltage restorer (DVR). The DVR was a power electronics device that was able to compensate voltage sags on critical loads dynamically. The compensating signals are determined dynamically based on the difference between desired and measured values. The control strategy adopted for generating reference signal plays a key role in deciding the dynamic behavior of a system. This work proposes a novel control algorithm for simultaneous sag compensation. The salient advantages of the proposed method are compensating long duration deeper voltage sags, both for 1 phase and three phase voltage sag. The proposed method has been simulated with MATLAB Simulink to show the applicability of it rather than the other previous control methods of DVR.
Biofilm’s Role in Chronic Cholesteatomatous Otitis Media

Cholesteatoma is a destructive lesion involving the temporal bone, which may induce severe complications due to its expansion and erosion of adjacent structures. Bacterial biofilm plays a crucial role in the pathogenesis of many otolaryngologic inflammatory/infectious chronic diseases. In this pilot study, we investigated, by means of cultural examination and with scanning electron microscope, the presence of bacterial biofilm in a series of samples from the epitympanic and mastoid region in patients affected by cholesteatoma and from the promontory region in patients with healthy mucosa who were undergoing to stapes surgery. The preliminary data support the association between biofilm and cholesteatoma (81.3% of the cases) and allow us to hypothesize that keratinized matrix of cholesteatoma may represent the ideal substrate for biofilm colonization and survival; this finding is consistent with the clinical course of aural cholesteatoma, characterized by recurrent exacerbations and recalcitrant course.
CD40 Ligand Protects from TRAIL-Induced Apoptosis in Follicular Lymphomas through NF-κB Activation and Up-Regulation of c-FLIP and Bcl-xL1

The TNF family member TRAIL is emerging as a promising cytotoxic molecule for antitumor therapy. However, its mechanism of action and the possible modulation of its effect by the microenvironment in follicular lymphomas (FL) remain unknown. We show here that TRAIL is cytotoxic only against FL B cells and not against normal B cells, and that DR4 is the main receptor involved in the initiation of the apoptotic cascade. However, the engagement of CD40 by its ligand, mainly expressed on a specific germinal center CD4+ T cell subpopulation, counteracts TRAIL-induced apoptosis in FL B cells. CD40 induces a rapid RNA and protein up-regulation of c-FLIP and Bcl-xL. The induction of these antiapoptotic molecules as well as the inhibition of TRAIL-induced apoptosis by CD40 is partially abolished when NF-κB activity is inhibited by a selective inhibitor, BAY 117085. Thus, the antiapoptotic signaling of CD40, which interferes with TRAIL-induced apoptosis in FL B cells, involves NF-κB-mediated induction of c-FLIP and Bcl-xL which can respectively interfere with caspase 8 activation or mitochondrial-mediated apoptosis. These findings suggest that a cotreatment with TRAIL and an inhibitor of NF-κB signaling or a blocking anti-CD40 Ab could be of great interest in FL therapy.
The Role of Superposition Techniques in Thermal Management

It is well-known that the performance and reliability of integrated circuits and other electronics are functions of operating temperature. The accurate prediction of temperature distributions for such applications poses engineering challenges due to many factors, including complex convection flows, non-uniform thermal boundary conditions, extrapolation to operation in extreme environments, and demanding steady-state and transient design requirements. In addition, the ever-increasing heat dissipation in a smaller package volume requires solutions with ever-increasing heat transfer and heat capacity. Thermal analysis and prediction based on superposition techniques are currently not as well-known as the use of numerical simulation tools readily available today. However, they are a powerful alternative to numerical simulation tools, especially for the complex scenarios that arise in this application. Superposition techniques can be applied to the design and interpretation of experiments and numerical simulations, and have the potential to form the building blocks of engineering tools that are more generally applicable to a wide range of challenging heat transfer problems
Constraining the electron densities in DFT method as an effective way for ab initio studies of metal-catalyzed reactions

The use of hybrid ab initio QM/MM methods in studies of metalloenzymes and related systems presents a major challenge to computational chemists. Methods that include the metal ion in the quantum mechanical region should also include the ligands of the metal in this region. Such a treatment, however, should be very demanding if one is interested in performing the configurational averaging needed for proper calculations of activation free energies. In the present work we examine the ability of the frozen DFT (FDFT) and the constrained DFT (CDFT) approaches to be used in ab initio studies of metal-catalyzed reactions, while allowing for an effective QM (rather than a QM/MM) treatment of the reacting complex. These approaches allow one to treat the entire enzyme by ab initio DFT methods, while confining the SCF calculations to a relatively small subsystem and keeping the electron density of the rest of the system frozen (or constrained). It is found that the FDFT and CDFT models can reproduce the trend obtained by a full DFT calculation of a proton transfer between two water molecules in a (Im)3Zn2+(H2O)2 system. This and related test cases indicate that our approximated models should be capable of providing a reliable representation of the energetics of metalloenzymes. The reasons for the special efficiency of the FDFT approach are clarified, and the strategies that can Correspondence to: A. Warshel; e-mail: warshel@invitro.usc. edu Contract/grant sponsor: NIH; contract/grant number: GM24491 Contract/grant sponsor: NSF; contract/grant number: MCB9808038 Contract/grant sponsor: Swiss National Science Foundation; contract/grant number: 10-49037.96 Journal of Computational Chemistry, Vol. 21, No. 16, 1554–1561 (2000) c © 2000 John Wiley & Sons, Inc. AB INITIO STUDIES OF METAL-CATALYZED REACTIONS be used in FDFT studies of metalloenzymes are outlined. c © 2000 John Wiley & Sons, Inc. J Comput Chem 21: 1554–1561, 2000
Production of enantiopure styrene oxide by recombinant Escherichia coli synthesizing a two-component styrene monooxygenase.

A whole cell biocatalytic process was developed to enable the efficient oxidation of styrene to chiral (S)-styrene oxide with an enantiomeric excess better than 99%. Recombinant Escherichia coli cells were employed to express the genes styAB encoding the styrene monooxygenase of Pseudomonas sp. strain VLB120 from an expression plasmid utilizing the alk regulatory system of P. oleovorans GPo1. The strains reached specific activities of up to 70 U* (g cell dry weight)(-1) in shake-flask experiments with glucose as the carbon source. An efficient two-liquid phase fed-batch process was established for the production of (S)-styrene oxide with hexadecane as an apolar carrier solvent and a nutrient feed consisting of glucose, magnesium sulfate, and yeast extract. Engineering of the phase fraction and the composition of organic phase and feed led to a 2-L scale process with maximal volumetric productivities of 2.2 g (S)-styrene oxide per liter liquid volume per hour. This optimized process was based completely on defined medium and used bis(2-ethylhexyl)phthalate as the apolar carrier solvent, which together with substrate and inducer consisted of 50% of the total liquid volume. Using this system, we were able to produce per liter liquid volume 11 g of enantiopure (S)-styrene oxide in 10 h.