Miracle-dz/UniFAR-FTUs huggingface dataset:
Expression and clinical study of gastric carcinoma hsa-miR-204 in tissues of gastric adenocarcinoma patients

Objective: This study aimed to analyze the expression and clinical significance of gastric carcinoma hsamiR-204 in tissues of gastric adenocarcinoma patients. Methods: 106 gastric adenocarcinoma patients who received operative treatment in our hospital from January 2015 to January 2018 were selected as the objects of this study, and the gastric adenocarcinoma tissues were collected during the operation. At the same time, normal gastric tissues of 3 cm adjacent to the cancer (pathology showed no cancer cells) were collected as control. Reverse transcription-polymerase chain reaction (RT-PCR) was used to detect the expression of miR-204 in cell lines, normal gastric specimen and gastric adenocarcinoma specimen. The correlation between relative expression of miR-204 and pathological parameters in gastric adenocarcinoma tissues was analyzed. miR-204 was transfected into human gastric cancer cell lines, and the proliferation and apoptosis of human gastric cancer cell lines in the transfected and untransfected groups were compared. Results: (1) The relative expression of miR-204 in gastric adenocarcinoma specimen was 1.95±0.75, which was much lower than that of 4.02±1.28 in normal gastric specimen (P<0.05). (2) The expression levels of miR-204 in patients with moderate and good differentiation were higher than those in patients with poor differentiation (P<0.05); the expression level of miR-204 in patients with lymph node metastasis was lower than that in patients without lymph node metastasis (P<0.05); and the expression level of miR-204 in patients at stages I-II of TNM staging was higher than that in patients at stages III-IV (P<0.05). (3) The apoptosis rates of BGC823 and SGC7901 in the untransfected group were 8.29±0.22% and 4.05±0.25%, which were much lower than those of 9.15±0.25% and 6.52±0.32% in transfected group (P<0.05). (4) On the third day, the absorbances of BGC823 and SGC7901 were respectively 2.49±0.09 OD490 and 3.18±0.06 OD490 in untransfected group, which were higher than those in transfected group (P<0.05). Conclusion: During the occurrence and development of gastric adenocarcinoma, miR-204 may play an important role as a cancer suppressor gene and can be regarded as a new molecular marker to provide vital foundation for prognosis and treatment of gastric adenocarcinoma patients.
‘Rinrei’, a brassinosteroid‐deficient dwarf mutant of faba bean (Vicia faba L.)

A dwarf mutant of broad bean (Vicia faba L.), the variety Rinrei, has been created by γ-ray irradiation. Rinrei is characterized by dark green leaves and by reduced plant length, internode and petiole length, shoot weight, and number of branches. Genetic analysis of hybrids between Rinrei and two wild-type lines indicated that these characteristics are controlled by a single recessive gene. The phenotype of Rinrei was restored to that of the wild type by application of brassinolide, but not by GA 3 . Qualitative and quantitative analysis by gas chromatography-mass spectrometry indicated that 24-methylenecholesterol and isofucosterol accumulated in Rinrei to levels more than 30 times higher than in the wild type. In contrast, Rinrei had lower than wild-type levels of campesterol, sitosterol, and brassinosteroids. Therefore, Rinrei is a brassinosteroid-deficient mutant defective in sterol C-24 reduction. The gene was tentatively designated as brassinosteroid deficient dwarf 1, bddl, which seems to be a homologue of Arabidopsis dwfl (dim, cbbl) and pea Ikb.
CHARACTERIZATION OF FAT-SOLUBLE VITAMINS AND MINERAL NUTRIENT OF THE SEEDS OF Senna occidentalis FROM REGIONS AROUND ZARIA

The seeds of Senna occidentalis were collected from a farmland in Jama’a village, Zango-Shanu along Samaru road, Zaria, Kaduna State. The samples were pr pared and analyzed using UV-visible and AAS, respectively for contents of fat-soluble vitamins ( A, D, E, and K) and minerals (Na, P, K, Mg, Ca, Fe, Zn and Cu) compositions. The study showed that the vitamins A, D, E, and K contents were 2.432 mg/L, 0.487 mg/L, 17.459 mg/L, and 0.067 mg/L, respectively. So dium (Na), phosphorus (P), potassium (K), magnesium (Mg), calcium (Ca), iron (Fe), zinc (Zn) and copper (Cu) compositions of the seeds were 0.013 mg/L, 0.7 82 mg/L, 9.700 mg/L, 116.084 mg/L, 231.133 mg/L, 19.60 0 mg/L, 7.5947 mg/L and 457.965 mg/L.
The Antibacterial Efficacy of Antibiotic-Loaded Mesoporous Silica Nanoparticles

In recent years, several studies have been developed to control drug delivery and reduce the toxicity of drugs as well as to create novel biomedical applications. Mesoporous silica nanoparticles (MSNs) have attracted the attention of many researchers, who have studied these materials for use in many applications. MCM-41 particles have a unique pore size, a higher surface area, and are a good matrix for guest–host applications. The aim of this work is to study the efficacy of antibiotic-loaded MSNs. The MSNs particles were synthesized using a liquid crystal templating method, with n-cetyltrimethylammonium bromide (CTAB) as the surfactant template and tetraethyl orthosilicate (TEOS) as the silica source. These mesoporous materials were characterized using a Fourier transform infrared spectroscope, scanning electron microscopy, transmission electron microscopy (TEM), high-performance liquid chromatography, nitrogen adsorption/desorption, anddynamic light scattering. Amoxicillin and erythromycin were used as the model drugs. The antibacterial effect and mechanism of the MSNs was investigated for Grampositive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli) using time-kill assay testing. The results of the present study clearly showed a significance reduction in S. aureus after treatment with antibiotic-loaded MSNs. However, there was no significant reduction observed against E. coli after treatment with amoxicillin-loaded MSNs. This difference may be a result of the mode of action of bacteria. In addition, TEM analyzed the bacteria treated with antibiotic-loaded MSNs. This study could contribute to a new antibacterial treatment and could lead to a reduction in the toxicity of drug in the future. Drug delivery systems have valuable applications in various fields; however, further investigation is required in many areas, including neurosciences, cancer, and biomedical engineering. [Samar M. Alhabardi. The Antibacterial Efficacy of Antibiotic-Loaded Mesoporous Silica Nanoparticles. Life Sci J 2016;13(6):31-39]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite. com. 4. doi:10.7537/marslsj13061604.
A design of low leakage cache memory cell for high performance processors

Abstract The noises, when augmented with leakage, destabilize the data stored in cache (SRAM). So, a novel 7T cache memory cell with reduced leakages and improved read and write performance is proposed to address the mentioned issue. The proposed cell with its unique read assist circuit provides SNM-free read operation. It also provides improved write ability by performing a differential write operation. The performance of the proposed cell is compared with the Standard-6T and Dual-VT 7T (DVT-7T) cells at 32nm technology node in the subthreshold region by SPICE simulations. The proposed structure shows significant improvement over other cells in terms of Read Static Noise Margin (RSNM), Write Static Noise Margin (WSNM), Data Retention Voltage (DRV), critical write time (Tcrit), read current (Iread) and standby leakage current (Ileak) values. In addition it uses three MOS transistor based latch structure to reduce area overhead. The Proposed-7T structure improves RSNM, WSNM, Iread and Ileak over Standard-6T cell. Similarly, performance improvement is observed in RSNM, WSNM, Iread, Tcrit(‘0’), Tcrit(‘1’) and Ileak in comparison to the DVT-7T cell. A super cut-off CMOS scheme to reduce leakages further has been employed in the paper. A process corner analysis has been done to capture the effect of process variation on the performance of cells.
IMMOBILIZATION OF CELLULASE ENZYME IN CALCIUM ALGINATE GEL AND ITS IMMOBILIZED STABILITY

In this study, cellulase enzyme is immobilized in calcium alginate bead by entrapment method. Sodium alginate concentration used for alginate bead forming is 2%. Immobilized enzyme activity is evaluated on carboxymethyl cellulose (CMC). The maximum efficiency of enzyme immobilization is 83.645% with immobilized time 30 minute and bead diameter 3mm. The optimum pH value of immobilized enzyme and free enzyme is 4.5. The optimum temperature value of immobilized enzyme is higher than free enzyme, 60 o C and 55 o C respectively. Immobilized enzyme is more stable versus the change of pH and temperature of environment than free enzyme. Immobilized enzyme can stand in higher acidity and temperature than free enzyme. Immobilized cellulase could be reused many times. Immobilized enzyme activity remains 69.2% after 5 recycles and still 20.3% after 8 recycles.
Effect of Aflatoxin and Ochratoxin A on Biochemical Parameters in Broiler Chickens

The effect of dietary aflatoxin (AF, 0.5, 1 and 2 ppm) and ochratoxin (OA, 1,2 and 4 ppm) either singly or in combinations on liver lipid and serum organic constituents was studied in commercial broiler chicks. An increase (P<0.05) in the liver lipid content was recorded in chicks fed 1 and 2 ppm AF, 4 ppm of OA and all combinations of these toxins. Serum protein concentration was reduced (P<0.05) at all the levels of toxins except 1 ppm of OA. Combination of 2ppm AF and 4 ppm OA caused maximum depression in serum protein concentration. Elevation (P<0.05) in serum bilirubin content was observed in chicks fed 2 ppm AF and combination of 2 ppm AF with 4 ppm OA. Uric acid increased significantly at 2 and 4 ppm of OA and their combinations with 1 and 2 ppm AF. Serum creatinine increased significantly in chicks fed 4 ppm OA and in combinations of 1ppm AF with 2 ppm OA and 2 ppm AF with 4 ppm OA. It is concluded that AF and OA at levels of 2 ppm and 4ppm, respectively either alone or in combination caused significant increase in liver lipids, serum bilirubin, uric acid and creatinine concentrations where as the serum protein concentration was decreased.
An Analytical Approach WLAN Standard

— In wireless medium, requirement of high frequency is increasing day by day. For high frequency based system data rates should be high. In unguided media, as signal tr distance and due to interference of noise, there is error in phase and frequency and we get a deviated output. In view of this, We are motivated to design a low power frequency synthesizer which would provide a low locking time, low settling t value of damping factor to provide a efficient frequency response at the output end. The proposed design aspect is for high frequency which is implemented in IEEE 802.11(a) WLAN standard and OFDM technology, WCDMA, Bluetooth technology, high frequency processor. We have used Microwind 3.1 45nm technology and ADS as design tool to execute propose design.
Assessment of the content of selected mineral components in daily food rations of haemodialysed patients

Material and method. The study involved 85 haemodialysed patients who, based on BMI (kg/m2), were allocated into three research groups of women: normal-weight group n=16 (38.1%), overweight group n=17 (40.5%) and obesity group n=9 (21.4%) and 3 groups of men: normal-weight group n=18 (41.9%), overweight group n=17 (39,5%) and obesity group n=8 (18.6%). The previous day 24 h dietary recall method was applied to assess the daily food ration (with regard to energetic value and intake of selected mineral components). The daily food rations were analysed using the “Dietetyk 2” computer program of the Institute of Food and Nutrition in Warsaw. The calculations were performed using the Statistica 6.0 program and the results were compared to the nutritional standards for haemodialysed subjects.
Security constrained optimal power flow in a power system based on energy storage system with high wind penetration

This study is focused on assessing the effect of energy storage system (ESS) presence on security improvement of power systems hosting remarkable renewable energy resources. To this end, ESS presence is suitably included in security-constrained optimal power flow (SCOPF) model; the required technical amendments are hence considered. To launch a realistic model, ramping constraints of thermal units are also taken into account which limit the generators from completely responding to power shortfalls. Considering a high penetration level of renewable generations, different scenarios of outages in transmission lines and generators are simulated to measure the line outage distribution factor (LODF) and power transfer distribution factor (PTDF). also, in order to illustrate the economic impact of wind power generation curtailment and load shedding, two penalty parameters VWC and VOLL are considered in the model. Two test systems, including a PJM 5-bus system and an IEEE 24-bus RTS, are put under numerical studies to assess the possible impact of ESS on security improvement of the investigated systems. The obtained results are discussed in depth.
Development of Amino Acid Balanced Food Systems Based on Wheat Flour and Oilseed Meal

The analysis of the main methods of increasing the nutritional and biological value of wheat flour has been conducted. Considerable attention is paid to the issue of adjusting the protein content in flour due to additives. The relevance of improving the amino acid composition of flour protein is emphasized. The feasibility of comprehensive studies for the development of food system formulations with a balanced amino acid composition based on wheat flour and oilseed meal is substantiated. The amino acid content has been experimentally determined and the biological value of raw materials proteins for food systems which are sunflower and soybean meal has been calculated. The mixture composition of sunflower and soybean meal with an improved amino acid composition has been scientifically substantiated. It has been found that the protein composition of the meal mixture is maximally close to the reference in terms of the content of leucine, lysine and the amount of sulfur-containing amino acids (methionine, cystine). The score of isoleucine, tryptophan, phenylalanine and tyrosine in the protein composition of oilseed meal is 1.1–1.47 times higher than the reference. The amino acid composition has been calculated and the biological value of the protein of food systems containing 80–90 % wheat flour and 10–20 % composition of soybean and sunflower meal with improved amino acid composition has been determined. It has been found that the formulation of the food system containing 20 % of the composition of meal mixture and 80 % of wheat flour has the greatest biological value in comparison with wheat flour. In this food system, the limited amino acids – lysine and sulfur-containing (methionine and cystine) are the closest to the reference one and are 67.68 % and 70.12 %. The fatty acid composition has been experimentally determined. The biological effectiveness of the fats of the developed food systems has been calculated. The closest to the fatty acid ratio recommended by nutritionists is the food system with a ratio of meal mixture: wheat flour of 20:80. The resulting formulations of food systems will be useful in technologies of flour products with high biological value.
Effects of light and fertilization on arbuscular mycorrhizal colonization and growth of tropical rain-forest Syzygium tree seedlings

This study investigated the effects of light and soil fertility, on arbuscular mycorrhizal fungi (AMF) colonization, and the growth responses (height and dry mass) of Syzygium seedlings. Seedlings of four Syzygium spp. were grown for 2 y in six different light treatments at the research station of the Sinharaja Forest, Sri Lanka. The light treatments exposed seedlings to: (1) 3%; (2) 16%; (3) 50%; (4) 100% of full sun (control); (5) short periods (2 h d−1) of direct sunlight; and (6) long periods (6 h d−1) of direct sunlight. In the 16% of full sun treatment five sets of fertilizer applications supplied: (1) magnesium; (2) potassium; (3) phosphorus; (4) all three nutrients combined; and (5) no fertilizer (control). The Syzygium species had the greatest mycorrhizal colonization in brighter treatments that provided direct light. Comparison across species revealed S. firmum to have moderate mycorrhizal colonization but high total dry mass. Syzygium operculatum had high percentages of mycorrhizal colonization while S. rubicundum had low percentages of mycorrhizal colonization especially in deep shade. Syzygium makul showed moderate levels of mycorrhizal colonization and dry mass, but low height growth. Among fertilizer applications, phosphorus enhanced seedling growth and mycorrhizal colonization for all species. However, species showed decreased growth with high amounts of potassium and combined fertilizer applications. Results suggest that AMF colonization will be highest, and Syzygium spp. growth greatest, beneath canopy openings large enough to receive direct sun in phosphorus-rich soils.
Self-Efficacy And Job Commitment Of Business Studies Teachers In Public Secondary Schools In Ogba/Ndoni/Egbema Local Government Area, Rivers State

This study examined the relationship between self-efficacy and job commitment of Business Studies teachers in public secondary schools in Ogba/Ndoni/Egbema Local Government Area, Rivers State. A correlational research design guided the study. The population comprised 67 Business Studies teachers in 24 public secondary schools in ONELGA which formed the sample due to the small size of the population. Two research questions were answered while two hypotheses were tested at 0.05 level of significance. A validated 20 item self-structured instruments titled: “Business Studies Teacher SelfEfficacy Questionnaire” and “Teachers Job Involvement Scale Questionnaire” were used for data collection. The instruments were designed using four point modified Likert rating scale of Strongly Agree (SA) = 4 points, Agree (A) = 3 points, Disagree (D) = 2 points and Strongly Disagree (SD) = 1 point. The reliability co-efficient of the instrument was established at 0.80 using Pearson Product Moment Correlation Co-efficient. Data collected were analyzed using mean and standard deviation to answer the research questions while Pearson Product Moment Correlation Co-efficient statistics was used to test the hypotheses. It was found among others that Business Studies teachers‟ remuneration as selfefficacy has a relationship with their effectiveness on the job. It was recommended among others that the government should increase the efficacy and job involvement of Business Studies teachers by providing necessary conditions, such as payment of leave bonuses, implementation of teachers new salary structure and increment, payment of bonuses, getting administrative support, provision of quality equipment for teaching and adequate classroom furniture.
PARASITOIDS AND PREDATORS OF THE DOUGLAS-FIR TUSSOCK MOTH, ORGYIA PSEUDOTSUGATA (LEPIDOPTERA: LYMANTRIDAE), IN LOW TO MODERATE POPULATIONS IN CENTRAL CALIFORNIA

Abstract Douglas-fir tussock moth, Orgyia pseudotsugata (McDunnough), populations were studied on white fir at four areas in central Sierra Nevada mountains of California during 1971–73. Life tables were constructed for four populations in El Dorado County. The number of eggs per egg mass decreased and the percentage eggs parasitized doubled with declining moth populations. Hymenopterous parasitoids were collected from all immature stages of the moth: one egg parasitoid, Telenomus californicus Ashmead, six species of larval parasitoids, principally, Hyposoter sp. , and 13 species of larval–pupal parasitoids. Tachinids were predominant and accounted for 73% of the parasitoidism of the cocoons in 1971. The apparent mortality of female pupae due to the parasitoid complex was greater than 97% in 1971 and 75% in 1972. One population in Placer County collapsed in 1971 apparently due to a combination of heat exhaustion and low levels of virus infection. Other defoliators, spiders, and several predatory insect species were collected from the foliage samples simultaneously with the tussock moth during larval sampling. Twelve species of "free living" spiders which could be capable of preying on the defoliator complex of white fir were collected. Parasitoids and predators appear to be potentially important biotic factors at low to moderate host population levels. This is the first recorded case where an agent other than the nucleopolyhedrosis virus has been responsible for the collapse of a Douglas-fir tussock moth population.
Optimization Algorithm Parameter Correlation with Objective Function Features

— This paper details a portion of an ongoing research project involving determining near-optimal optimization algorithm parameter values based on high-level features of underlying objective functions. In the paper, we present a general method for determining the statistical correlation between an optimization algorithm parameter value and a particular attribute of the underlying objective function, and apply this method to investigate the signiﬁcance of population size within the Particle Swarm Optimization (PSO) algorithm with respect to the number of dimensions of the objective function. We demonstrate how this approach can yield improved optimization algorithm performance with minimal computational cost, and examine how the approach can be applied generally for any optimization task.
Influence of Quality Counseling on Performance of Family Planning Programs in Kuresoi North Sub-County, Nakuru County, Kenya

This study investigated quality counseling influence on performance of family planning programs in Kuresoi North Sub-County, Nakuru County, Kenya. The study was founded on the theory of constraint and adopted a pragmatism paradigm. It applied descriptive research method using mixed method approach to investigate the influence of quality counseling on performance of family planning program in Kuresoi North Sub-County, Nakuru County, Kenya. The target population in the study was women of reproductive age in 33,482 households distributed in the four Wards of Kuresoi North Sub-County and 19 health management leaders in-charge of all government health facilities offering family planning services in the Sub-County. A sample size of 400 of women of reproductive age and 19 nursing officers in-charge of government health facilities was utilized. The data collection tools used were questionnaire, interview guide, and observation checklist for women of reproductive age and the interview guide for the health facility managers. The research study adopted stratified sampling method. Qualitative data was analyzed according to themes and patterns and then summarizing the data and linking it to objectives and hypothesis. The study findings indicate that there is moderate quality counseling exhibited pertaining to family planning in the dispensaries and health centers located in Kuresoi North Sub-County. Further findings exhibited that there was a significant and strong positive individual correlation between quality counseling and performance of family planning program in Kuresoi North Sub-County. Finally, the study findings also exhibited that there is a significant positive relationship between quality counseling and performance of family planning program in Kuresoi North Sub-County and it predicted the performance of family planning programmes. in Kuresoi North Sub-County.