Miracle-dz/UniFAR-FTUs huggingface dataset:
Lipoproteins and progesterone biosynthesis in the human ovary.

The highly vascularised ovarian luteal tissue is exposed to high-density lipoproteins (HDLs), and low-density lipoproteins (LDLs) in vivo. LDLs have been shown to stimulate human ovarian steroidogenesis, however the effects o f HDLs on progesterone production remain unclear. The present study investigates a role for HDLs in progesterone synthesis by human granulosa-lutein cells, and assesses the effects o f lipoprotein oxidation on the steroidogenic responses to HDLs and LDLs. Human follicular fluid contained HDLs with a lower cholesterol content, and a lower proportion o f apolipoprotein E containing particles compared to plasma HDLs. Despite these differences, HDLs (intrafollicular fluid and plasma), and LDLs significantly stimulated progesterone production by granulosa-lutein cells. The progesterone responses to HDLs and LDLs were unaffected by protein kinase C down-regulation. However, HDLs and LDLs increased cAMP accumulation, and synergised with maximally effective concentrations o f hCG and dibutyryl cAMP to increase progesterone production by granulosa-lutein cells over 24h. The HDL/LDL-hCG interactions required 24h incubation regardless o f whether cells were exposed simultaneously, or in sequence to hCG and HDL/LDL. At equal cholesterol content, HDLs increased progesterone production to a greater extent that LDLs, suggesting that the progesterone response to HDLs may involve mechanisms other than cholesterol delivery. In keeping with this proposal, HDLs interacted synergistically with maximally effective concentrations o f 22Rhydroxycholesterol. Moreover, increased concentrations o f prostaglandin E2, cAMP and progesterone by granulosa-lutein cells, in response to HDLs, were abolished in the presence o f a prostaglandin H synthase inhibitor. Human follicular fluids contained oxidatively modified HDL, despite having high antioxidant concentrations. Regarding the consequence o f lipoprotein oxidation, lipoproteins oxidised in vitro, did not interact synergistically with hCG to increase progesterone production. Moreover, the effects o f oxidised lipoproteins were unaffected by leucocyte-depletion o f granulosa-lutein cells. While native HDLs and LDLs support progesterone production in vitro, the physiological significance o f native and oxidised lipoproteins in vivo, remains to be elucidated.
Comparative Study of RSA and Probabilistic Encryption/Decryption Algorithms

Networks are virtual windows to the people which allow remote access to geographically distant resources without having to be physically present. This is achieved by sending data back and forth in the network. But networks are vulnerable because of their inherent characteristic of facilitating remote access. Hence network security plays a vital role in real time environment as it protects loss and misuse of the data in the network. There are many applications and algorithms running behind the scene for providing security while transmitting data in the network. One of the most important components of network security is cryptography and it consists of many algorithms that protect user from the adversary like trapdoor, eavesdroppers, hackers etc. There are many well known algorithms which serves this purposes and each have its own advantages and disadvantages. The aim of this paper is to outline the key concepts involved in two algorithms namely Goldwasser-Micali encryption and most widely used RSA. Some of the metrics used for comparison are encryption time, decryption time and size of cipher text with varying plain text sizes which are the key considerations for choosing an encryption algorithm. The comparison of encryption and decryption time with varying cypher text sizes for both the algorithms using math lab code and preliminary observations are depicted in this paper.
The castor oil test in rats: An in vivo method to evaluate antipropulsive and antisecretory activity of antidiarrheals?

Castor oil‐induced diarrhea in rats is described to be an appropriate model of the complex, prolonged processes of hypersecretion and accelerated transit that characterize secretory diarrhea. Suprofen, a prostaglandin biosynthesis inhibitor, was found to postpone diarrhea over a wide dose range, but suprofen failed to reduce the diarrheal excretion. In contrast to suprofen, loperamide not only increased the diarrhea‐free period but also produced a dose‐related decrease of the diarrheal excretion.
Komunikasi dakwah pensyarah pendidikan Islam terhadap pelajar di Politeknik Sultan Salahuddin Abdul Aziz Shah,Shah Alam, Selangor / Hasani Ghazali

Gejala keruntuhan akhlak khususnya di kalangan remaja semakin serius dan merumitkan seolah-olah menggambarkan mesej penyampaian ilmu pendidikan Islam di semua peringkat terutama di sekolah dan institut pengajian tinggi tidak mencapai objektif dan kurang berkesan. Kajian ini memberi tumpuan kepada aspek pelaksanaan komunikasi dakwah pensyarah dalam proses penyampaian pengajaran dan pembelajaran dan penerimaan pelajar terhadap penyampaian mereka. Secara lebih khusus, kajian mengenal pasti pelaksanaan komunikasi dakwah pensyarah pendidikan Islam dari aspek tugas pensyarah sebagai da’i, media komunikasi yang digunakan, penggunaan uslub dalam penyampaian, mesej dalam penyampaian dan halangan dalam komunikasi dakwah pensyarah. Selain itu, kajian ini memberi tumpuan kepada penerimaan pelajar terhadap komunikasi dakwah pensyarah pendidikan Islam terhadap lima aspek iaitu tugas pensyarah sebagai da’i, penggunaan media dalam penyampaian, bentuk penyampaian mesej, uslub dalam penyampaian dan maklum balas/respon pelajar terhadap komunikasi dakwah pensyarah. Kajian ini menggunakan metode kajian perpustakaan dan kajian lapangan.Responden terdiri daripada 16 orang pensyarah pendidikan Islam dan 240 orang pelajar Tamadun Islam sesi Jun 2013 yang dipilih secara rawak. Pengumpulan data berdasarkan temu bual bersama pensyarah dan pengedaran soal selidik kepada pelajar. Di samping itu, turut dilakukan observasi ketika pelaksanaan pengajaran dan pembelajaran dalam kalangan pensyarah di dalam bilik kuliah. Hasil kajian mendapati secara umumnya, para pelajar kurang memiliki penghayatan agama. Oleh itu, para pensyarah sebagai da’i melaksanakan pelbagai program dakwah, pengubah suaian sesi pembelajaran serta perhatian pelajar bagi memenuhi keperluan dakwah, psikologi dan fisiologi pelajar dengan penggunaan pelbagai media dan saluran serta pelbagai uslub yang sesuai. Walau bagaimana pun, kekurangan fasiliti dan kurang ilmu menjadi faktor halangan dalam penyampaian dakwah pensyarah. Bagi pihak pelajar pula, responden menerima secara positif pelaksanaan komunikasi dakwah yang berlaku antara pensyarah dan pelajar. Kajian mendapati pelajar meletakkan kredibiliti yang tinggi terhadap tugas pensyarah sebagai da’i dan setuju dengan pemilihan media yang digunakan oleh pensyarah sebagai saluran penyampaian dakwah. Pelajar juga bersetuju menerima mesej penyampaian pensyarah dengan baik dan mengakui uslub pengajaran yang digunakan adalah sesuai. Walau bagaimana pun masih terdapat kelemahan dan kepincangan yang perlu diperbaiki terutama aspek kekurangan fasiliti dan ilmu yang memberi kesan besar terhadap pelaksanaan komunikasi dakwah dalam penyampaian pengajaran dan pembelajaran.
DISTINCTION BRUIT-CHAOS APPLIQUEE AUX MESURES DE FLUX ROUTIERS

Ce rapport fait suite a une demarche que nous avons entreprise il ya deux ans, pour tenter d'appliquer la theorie du chaos a la problematique de la prevision a court terme du trafic routier (cf RTS N45). Nous remercions a cette occasion, Madame Monique DUBOIS et Monsieur Pierre BERGE specialistes de cette theorie et Directeurs de Recherche au CEA, pour leur precieux conseils, qui nous ont amene a travailler avec l'INSA de Rouen (URA CNRS 230). Nous remercions particulierement Nathalie LETAIEF et Claude ROZE, Chercheurs de ce laboratoire, d'avoir realise le present rapport. La suite de ce travail ,fait, actuellement, l'objet d'un stage de fin d'etudes d'ingenieur qui se deroule dans ce meme Laboratoire. Un rapport de recherche a paraitre fera la synthese de l'ensemble de ces travaux. (A)
Profil Gériatrique Selon l'Instrument Identification Systématique des Aînés à Risque ( ISAR ) au Service des Urgences d'un Centre Hospitalier Universitaire

Parmi les personnes âgées fragiles, le risque de déclin fonctionnel lié à une hospitalisation est augmenté, probablement autant par la rupture de l’équilibre global que par la pathologie même qui motive la prise en charge hospitalière [1-2]. L’inadéquation entre le profil de fragilité et les structures traditionnelles de l’hôpital d’une part, et la méconnaissance des indicateurs de ce profil d’autre part, exposent la population âgée aux risques de pertes de capacités fonctionnelles, de placement en institution et de réadmissions à l’hôpital [3-5]. Ces risques peuvent être infléchis favorablement si, dès l’admission, les indicateurs de ces risques sont pris en compte et que des interventions ciblées selon le modèle de l’évaluation gériatrique standardisée sont mises en œuvre durant le séjour avec une planification proactive de la sortie [6-10]. C’est avec cette conception de soins que les services spécialisés en gériatrie, appelés aussi unités de court séjour gériatrique (UCSG), ont été mis en place dans plusieurs pays depuis plus de 30 ans [11]. La principale compétence des unités de gériatrie se trouve dans la capacité de l’équipe hospitalière pluridisciplinaire à répondre à trois défis : – La prise en charge de la polypathologie, en quoi elle
DEGREE OF PROMINENCE OF PALATAL EXOSTOSIS AND SPECIFICITIES OF FABRICATION OF TOTAL PROSTHESIS

Torus palatinus (TP) is a benign, slow-growing bony protrusion of varying shape and size, most commonly situated along the sutura mediana in the frontal or back third of the hard palate. A large discrepancy in the resilience of its musocal envelope and adjacent mucosa (resilient zones by Shroeder), especially in cases with large protrusions, can bring about the problems in the manufacture of total prostheses and especially in wearing them („rocking“, fracture of the prosthesis along the palatal midline, injury to the mucosa in the region of TP, etc.). This paper presents in extenso the plan of the administered prosthetic treatment of a female patient aged 62 years, admitted to the clinic because of total edentulousness of the upper jaw and a very distinct TP. After clinical examination and necessary consultations with an oral surgeon, using the method of selective decompression of TP during the functional imprint acquisition, an upper total prosthesis was manufactured with a small chamber in the region. Possible complications mentioned above were thus avoided, and the patient adapted to the prosthesis completely after one common reocclusion and two control visits. Acta Medica Medianae 2011;50(1):54-59.
Music before Dental Surgery Suppresses Sympathetic Activity Derived from Preoperative Anxiety

The aim of this study was to estimate the relieving effect of music intervention on preoperative anxiety by using heart rate variability (HRV) analysis. In this randomized controlled trial, 86 adult patients were scheduled to undergo impacted tooth extraction under intravenous sedation and local anesthesia and were classified as either fearful or nonfearful based on a questionnaire. Thereafter, the patients were subdivided into 2 groups: those who listened to music from the time that they arrived at the outpatient clinic until immediately before entering the operating room and those who did not listen to music. The effect of music intervention was evaluated by assessing 1) the low-frequency/high-frequency ratio of HRV, in which positive changes indicate increased sympathetic nervous activity, and 2) the coefficient of component variance for high frequency, in which positive changes indicate increased parasympathetic nervous activity, assessed by means of HRV analysis. Subjective preoperative anxiety was evaluated on a visual analog scale. For fearful patients, the mean magnitude of low-frequency/high frequency changes from baseline among those who listened to music was significantly lower as compared with those who did not listen to music (in the private room: −1.45 ± 1.88 vs. 1.05 ± 1.88, P = 0.0096, 95% confidence interval of effect size = −4.52 to −0.48, Cohen’s d = −0.75; in the operating waiting room: −2.18 ± 2.39 vs. −0.10 ± 3.37, P = 0.011, 95% confidence interval of effect size = −3.94 to −0.22, Cohen’s d = −0.71, respectively). Visual analog scale scores were also significantly different. Coefficient of component variance for high frequency and heart rate did not differ significantly between the 2 groups. From the perspective of autonomic nervous activity, music intervention is useful for relieving anxiety in patients with dental fear before they enter a dental outpatient operating room. Music intervention may relieve anxiety by reducing sympathetic nervous activity, while parasympathetic nervous activity is not involved (UMIN000016882). Knowledge Transfer Statement: The results of this study revealed that music intervention is useful for clinicians when planning preoperative anxiety management of patients with dental fear who undergo impacted tooth extraction under intravenous sedation and local anesthesia. As a bridging intervention, music intervention enables stress management to continue uninterrupted from the patient’s arrival at the dental outpatient clinic to intravenous sedation until completion of the dental surgery. With consideration of cost-effectiveness, absence of adverse physical effects, immediate effect, safety in terms of not using drugs, and lack of concerns about recovery, this information could lead to more appropriate decisions regarding anxiety management in dentistry.
Protocoles d'interaction cerveau-machine pour améliorer la performance d'attention visuo-spatiale chez l'homme

L'attention visuospatiale est un mecanisme de selection et de traitement d'information qui se manifeste explicitement par l'orientation de la tete ou du regard. En anticipation d'une nouvelle information, le foyer de l'attention s'oriente implicitement en vision peripherique pour dissocier l'orientation du regard et du foyer implicite vers deux emplacements distincts. Dans cette situation, la reaction a une cible qui apparait a l'emplacement du foyer implicite s'ameliore par rapport aux autres cibles qui pourraient s'afficher dans un emplacement non-attendu. La problematique de la these est d'etudier comment detecter l'emplacement du foyer de l'attention implicite par decodage de l'activite cerebrale mesuree en electro-encephalographie (EEG) avant l'affichage d'une cible visuelle dans 3 experiences realisees chez des sujets sains. La premiere experience aborde la problematique dans une condition ou l'indication sur l'emplacement de la cible est globalement non-informative pour les sujets. Cependant, leur activite cerebrale suggere que ce type d'indication a tendance a induire un etat d'alerte, de preparation ou d'orientation de l'attention dans le temps plutot que dans l'espace. En lien avec ce resultat, la deuxieme experience aborde la problematique dans une condition ambigue ou l'attention du sujet s'oriente vers un emplacement sans lien systematique avec le contenu des indications.
Statistical Imitation Learning in Sequential Object Manipulation Tasks

The purpose of this volume is to encourage and inspire the continual invention of robot manipulators for science and the good of humanity. The concepts of artificial intelligence combined with the engineering and technology of feedback control, have great potential for new, useful and exciting machines. The concept of eclecticism for the design, development, simulation and implementation of a real time controller for an intelligent, vision guided robots is now being explored. The dream of an eclectic perceptual, creative controller that can select its own tasks and perform autonomous operations with reliability and dependability is starting to evolve. We have not yet reached this stage but a careful study of the contents will start one on the exciting journey that could lead to many inventions and successful solutions.
Contribution à l'approximation numérique des systèmes hyperboliques

Dans ce travail, on s'interesse a plusieurs aspects de l'approximation numerique des systemes hyperboliques de lois de conservation. La premiere partie est dediee a la construction de schemas d'ordre eleve sur des maillages 2D non structures. On developpe une nouvelle technique de reconstruction de gradients basee sur l'ecriture de deux schemas MUSCL sur deux maillages imbriques. Cette procedure augmente le nombre d'inconnues numeriques, mais permet d'approcher la solution avec une grande precision. Dans la deuxieme partie, on etudie la stabilite des schemas d'ordre eleve. On montre dans un premier temps que les inegalites d'entropie discretes usuelles verifiees par les schemas d'ordre eleve ne sont pas pertinentes pour assurer le bon comportement dans le regime de convergence. On propose alors une extension des techniques de limitation {\it a posteriori} pour forcer la verification des inegalites d'entropie discretes requises. Dans la derniere partie, on s'interesse a la construction de schemas well-balanced pour le modele de Saint-Venant, le modele de Ripa et les equations d'Euler avec gravite. On propose plusieurs strategies permettant d'obtenir des schemas numeriques capables de preserver tous les regimes stationnaires au repos. On developpe egalement des extensions d'ordre eleve.
De l’invention à l’innovation, l’énigmatique mutation

Dans cet article, il s’agit de s’interroger pourquoi les technologies, mises en œuvre au sein du dispositif formel, ne depassent pas le stade d’une utilisation, au mieux conforme au mode d’emploi, d’autant que celles qui se pratiquent en marge des prescriptions formelles sont appropriees, adaptees, voire « detournees » de leurs usages initiaux. Bien qu’elles naissent toujours en dehors ou en marge du dispositif formel, ces inventions restent, cependant, a l’etat experimental, ne depassant guere le stade du prototype. Nous souhaiterions montrer que, si les organisations formelles s’averent steriles, les pratiques informelles se revelent plus inventives, sans, pour autant, parvenir a traduire leurs inventions en innovations, c’est-a-dire, reproductibles et commercialisables au sens Schumpeterien.
Mesenteric Schwannoma: A Case Report and Review of the Literature

Schwannomas are neurogenic, benign, well-circumscribed, and encapsulated tumors that arise from Schwann cells. Primary mesenteric schwannoma is very rare. In this report, we describe a 79-year-old female who presented with epigastric discomfort caused by a schwannoma originating from the mesentery of the transverse colon, which was successfully treated with complete surgical resection. We review the reported cases of primary benign mesenteric schwannomas and discuss the clinical, radiological, pathological and immunohistochemical features.
Die Gestaltung der Arbeitsumgebung von Operatoren (k-)ein Platz für Innovationen? : Neue Interaktionsformen für den Leitstand der Zukunft

Kurzfassung In diesem Beitrag wird die Gestaltung einer neuen Arbeitsumgebung für Operatoren in Leitständen diskutiert. Hierbei werden zum einen die Vorund Nachteile bisheriger Entwicklungen der Mensch-Maschine-Schnittstelle beschrieben und zum anderen neue Technologien beleuchtet. Dabei werden Innovationen bezüglich ihrer Integrationsund Adaptionsmöglichkeiten für das Leitstandszenario mit seinen besonderen Anforderungen betrachtet, um Arbeitsabläufe zu optimieren und letztlich auch Fehlentscheidungen sowie Kosten zu reduzieren. Leitbild bei der Konzeptentwicklung sind die Prinzipien der realitätsbasierten Interaktion, welche den Operator bei der Ausübung seiner Tätigkeiten in natürlicher Weise unterstützen sollen.
Integrated work in a neighbourhood family centre

Abstract Individual family centres tend to develop tend the limes of either therapeutic work with referred families or mare general resource provision and community work approaches with the families in a particular neighbourhood. The article looks at the benefits of adopting an integrated programme which combines therapeutic work with a resource provision and a community work approach. The benefits are seen to be those of addressing the approach factors in the stress of individual families, encouraging participation, decreasing stigmatisation and aiding personal and group change. Issues of implementation are also discussed. Two of the most important of these are seen to be producing an appropriate and balanced local image of the centre and maintaining the child protection role.
A pervasive computing architecture fostering integration in patient centred communities of care

The paper shows how a pervasive computing architecture, CASMAS, and its associated modelling language can be used to support cooperation among the members of a patient-centred community of care and their digital devices. We also show how CASMAS can be augmented by the WOAD framework, which was developed independently to model and express declarative mechanisms of provision of awareness promoting information (API) in document-mediated communities. Parts of these mechanisms can be modelled on the basis of integrated care pathways taken from the medical specialist literature. We take the distributed hypertension monitoring case as an exemplifying and sufficiently complex scenario to show the feasibility and advantages of our semantically informed and modular approach. The scenario is then declined in terms of architectural components and cooperation-oriented mechanisms that are shared between the devices and entities of the designed community of care.
Maladie de Parkinson et épilepsie: hypothèse d'une incompatibilité biologique.

The case of a 74-year-old woman, affected since the age of 20 by generalized convulsive fits and who began to show at the age of 63 signs of Parkinson's disease is reported. The epileptic features showed no change while Parkinson's disease got worse. Further, every convulsive fit was followed by a transitory improvement of the extrapyramidal disorders. After a review of the literature on the rare association of Parkinson's disease with epilepsy, the hypothesis of a biological incompatibility between the two diseases is considered.
Betere temperatuurverdeling door regelbare gevelverwarming

Het oplossen van horizontale temperatuurverschillen is al jarenlang een probleem waar veel ondernemers mee worstelen. De invloed van de windrichting wordt vaak aangevoerd als belangrijke oorzaak waardoor het onmogelijk zou zijn deze problemen op een afdoende manier op te lossen. Het resultaat van het onderzoek door A&F toont aan dat toepassing van een regelbaar gevel een afdoende oplossing biedt die tevens economische voordelen biedt. Temperatuurverschillen in de kas ontstaan door variatie in de warmteafgifte van het verwarmingssysteem of door lekventilatie. Aan de gevel wordt het warmteverlies naar de omgeving mede bepaald door de windrichting en snelheid. Temperatuurverschillen in de kas zorgen voor nadelige effecten op de groei, kwaliteit, ontstaan van ziektes en daarmee op de productie.