Miracle-dz/UniFAR-FTUs huggingface dataset:
The role of the Polochic Fault as part of the North American and Caribbean Plate boundary: Insights from the infill of the Lake Izabal Basin

The Lake Izabal Basin in Guatemala is a major pull‐apart basin along the sinistral Polochic Fault, which is part of the North American and Caribbean plate boundary. The basin infill contains information about the tectonic and sedimentological processes that have imparted a significant control on its sedimentary section. The inception of the basin has been linked to the relative importance of the Polochic Fault in the tectonic history of the plate boundary; yet, its sedimentological record and its inception age have been poorly documented. This study integrates diverse datasets, including industry reports, well logs and reports, well cuttings, vintage seismic data, outcrop observations and geochronological data to constrain the initial infill and age of inception of the basin. The integrated data show that during the Oligocene–Miocene, a marine carbonate platform was established in the region which was later uplifted and eroded in the early Miocene. The fluvial–lacustrine deposits above this carbonate platform are part of the initial infill of the basin and are constrained with zircon weighted‐mean 206Pb/238U ages of 12.060 ± 0.008 from a volcanic tuff ~30 m above the unconformity. Sandstone, mudstone and coal dominate the interval from 12 to 4 Ma, with an increase in conglomerate correlating to the uplift of the Mico Mountains and San Gil Hill at 4 Ma. Fault switch activity between the Polochic and Motagua faults has been hypothesized to explain total offset along the Polochic Fault and the geologic and geodetic slip rates along the two faults. The 12 Ma age determined for the initial infill of the basin confirms this hypothesis. Consequently, our study confirms that at ~12 Ma the Polochic Fault served as the main fault of the plate boundary with inferred slip rates ranging from 13 to 21 mm/yr with a strong possibility that the Polochic Fault was, at some point between 15 Ma and 7 Ma, the only active fault of the plate boundary. The results of this study show that tectonic records preserved in sediments of strike‐slip basins improve the understanding of the relative significance of individual faults and the implications with respect to strain partitioning throughout its tectonic history.
Relationship between Bioactive Components and Antioxidant Capacity of Some Commonly Consumed Vegetables in Punjab

Fruits and vegetables have been gaining great attention among consumers because they play an important role in the human health and diet. Being considered as wholesome foods, the nutritional value of vegetables and fruits is attributed to the optimal mix of phytochemicals which are mainly constituted by fibres, natural antioxidants and bioactive components. Anti-oxidants are the substances which are capable of inhibiting the oxidative stress in the body caused by production of free radicals during metabolic reactions in the body. These free radicals are the agents which are involved in the pathogenesis of various non-metabolic disorders and degenerative diseases such as diabetes, Parkinson’s and Alzheimer’s diseases, cancers, asthma and atherosclerosis (Podsedek, 2007; Dasgupta and De, 2007; Turkmen et al., 2005 and Cai et al., 2004). International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 8 Number 11 (2019) Journal homepage: http://www.ijcmas. com
Similar Glacial‐Interglacial δ15N Variations in Two MIS 13–10 Sediment Sequences in the Western North Atlantic Ocean: Changes in Nitrogen Sources, Denitrification, or Diagenesis?

We have determined total organic carbon‐mass accumulation rates (TOC‐MARs) and δ15N values in Marine Isotope Stages (MIS) 13–10 sediments from two oligotrophic parts of the western North Atlantic Ocean—Ocean Drilling Program (ODP) Site 1063 on the Bermuda Rise and Site 1058 on the Blake Outer Ridge. Both TOC‐MARs and δ15N values vary significantly in these depositional records. TOC‐MARs are highest in sediments deposited at Site 1063 during MIS 12 and MIS 10, implying marine productivity or TOC preservation increased at this location during glacial stages, and low TOC‐MARs during most of MIS 11 in Site 1063 sediment imply low rates during this warm interval. In contrast to the Site 1063 record, productivity or preservation appears to have been greater at Site 1058 during parts of the MIS 11 interglacial than during the glacial intervals. Unlike the TOC‐MAR records, δ15N values at both locations exhibit similar glacial‐interglacial alternations. Values peak during substage 11.3 and gradually decrease toward the terminations of MIS 12 and MIS 10. The similarity of the δ15N patterns at these two sites implies that nitrogen cycling at these locations is largely independent of changes in local surface production of organic matter, and the higher δ15N values are unlikely to result from denitrification. Instead, the δ15N alternations likely result from glacial‐interglacial alternations between higher rates of sediment delivery to these western North Atlantic locations during glacial periods that favored TOC preservation and lower rates during interglacials that allowed more TOC degradation and associated diagenetic alteration of its nitrogen isotopic composition, leading to higher sediment δ15N values.
Assessment of the role of gabapentin in patients with supratentorial tumours undergoing craniotomy under general anaesthesia: A double-blind randomised study

Abstract Background: Gabapentin attenuates the haemodynamics, decreases the catecholamine release and has a neuroprotective effect. The aim of the present study was to assess the effect of gabapentin in patients with supratentorial brain tumours undergoing craniotomy under general anaesthesia. Methods: A radial arterial line, central venous line and ventriculostomy catheters were inserted before surgery. Anaesthesia was induced with thiopental, fentanyl and atracurium and maintained with sevoflurane, fentanyl and atracurium infusion. The study included 160 patients classified randomly into two groups: Group G: The patients received gabapentin capsules 1200 mg orally 2 h before surgery. Group C: The patients received placebo capsules. Results: The heart rate, mean arterial blood pressure and intracranial pressure decreased significantly with gabapentin as compared to the control group (P < 0.05). The dose of fentanyl and end-tidal sevoflurane was lower with gabapentin than the control group (P < 0.05). The urine output was higher in the gabapentin group than the control group (P < 0.05). The Glasgow coma scale score was better in the gabapentin group as compared to the control group (P < 0.05). The incidence of nausea and vomiting was lower in the gabapentin group as compared to the control group (P < 0.05). Conclusions: Pre-operative administration of gabapentin in patients undergoing craniotomy under general anaesthesia minimised the fluctuations in haemodynamics, reduced the requirements for sevoflurane and fentanyl, decreased intracranial pressure and improved the outcomes. There were some side effects associated with gabapentin such as hypotension and bradycardia.
Location and Sizing of Battery Energy Storage Units in Low Voltage Distribution Networks

Proper planning of the installation of Battery Energy Storage Systems (BESSs) in distribution networks is needed to maximize the overall technical and economic benefits. The limited lifetime and relatively high cost of BESSs require appropriate decisions on their installation and deployment, in order to make the best investment. This paper proposes a comprehensive method to fully support the BESS location and sizing in a low-voltage (LV) network, taking into account the characteristics of the local generation and demand connected at the network nodes, and the time-variable generation and demand patterns. The proposed procedure aims to improve the overall network conditions, by considering both technical and economic aspects. An original approach is presented to consider both the planning and scheduling of BESSs in an LV system. This approach combines the properties of metaheuristics for BESS sizing and placement with a greedy algorithm to find viable BESS scheduling in a relatively short time considering a specified time horizon, and the application of decision theory concepts to obtain the final solution. The decision theory considers various scenarios with variable energy prices, the diffusion of local renewable generation, evolution of the local demand with the integration of electric vehicles, and a number of planning alternatives selected as the solutions with top-ranked objective functions of the operational schedules in the given scenarios. The proposed approach can be applied to energy communities where the local system operator only manages the portion of the electrical grid of the community and is responsible for providing secure and affordable electricity to its consumers.
Vers une vérification automatique des affirmations statistiques

Digital content is increasingly produced nowadays in a variety of media such as news and social network sites, personal Web sites, blogs etc. In particular, a large and dynamic part of such content is related to media-worthy events, whether of general interest (e.g., the war in Syria) or of specialized interest to a sub-community of users (e.g., sport events or genetically modified organisms). While such content is primarily meant for the human users (readers), interest is growing in its automatic analysis, understanding and exploitation. Within the ANR project ContentCheck, we are interested in developing textual and semantic tools for analyzing content shared through digital media. The proposed PhD project takes place within this contract, and will be developed based on the interactions with our partner from Le Monde. The PhD project aims at developing algorithms and tools for :Classifying and annotating mixed content (from articles, structured databases, social media etc.) based on an existing set of topics (or ontology) ;Information and relation extraction from a text which may comprise a statement to be fact-checked, with a particular focus on capturing the time dimension ; a sample statement is for instance « VAT on iron in France was the highest in Europe in 2015 ». Building structured queries from extracted information and relations, to be evaluated against reference databases used as trusted information against which facts can be checked.
Comparison of a static, independent balance protocol and the National Institute on Aging balance protocol on stability and risk of falling in the elderly

ABSTRACT Falls by the elderly are preceded by muscle weakness and deteriorated sensory input. The aim of this study was to compare the effectiveness of an independent static balance (ISB) protocol with the National Institute on Aging (NIA) supervised protocol for improving balance. Sixteen participants (age 88.6 ± 4.3 year) were randomly placed in the ISB or NIA group. Pre- and posttests included fall risk (FR), overall stability (OS), anterior/posterior index (API), and medial and lateral index (MLI). Training consisted of 20 min, 2 × weeks for 12 weeks. The NIA group demonstrated greater improvement in all variables compared to the ISB group except for FR; however, there were no significant differences (p > 0.05) between the groups among any dependent variable. Static balance exercises conducted independently led to similar improvements in balance and FR reduction as the highly supervised NIA protocol. Balance can be improved independently without close supervision thus allowing personnel to tend to other patients.
Associations Between Circulating Interleukin-17 Levels and Systemic Lupus Erythematosus and Between Interleukin-17 Gene Polymorphisms and Disease Susceptibility: A Meta-analysis

Objective. To systematically investigate the relationship between circulating interleukin-17 (IL-17) levels and systemic lupus erythematosus (SLE) and associations between polymorphisms in IL17 genes and SLE susceptibility. Methods. We performed a meta-analysis of serum/plasma IL-17 levels in patients with SLE and controls and evaluated the associations between the IL17A rs2275913, IL17F rs763780, and IL17F rs2397084 polymorphisms and IL17F copy number variations (CNVs) and risk of SLE. Results. Thirteen studies focusing on 2,096 patients with SLE and 2,587 controls were included. Our meta-analysis revealed that IL-17 levels were significantly higher in the SLE group than the control group (standardized mean difference=1.045, 95% confidence interval [95% CI]=0.521∼1.568, p＜0.001). Subgroup analysis using sample size showed increased IL-17 levels in samples from large (n＞100) but not small (n＜90) SLE groups. We found no evidence of associations between SLE and the IL17A rs2275913, IL17F rs763780, and IL17F rs2397084 polymorphisms. However, a significant association was found between SLE and IL17F CNVs in a pooled cohort of affected individuals compared to that in pooled controls (odd ratio=3.663, 95% CI=2.466∼5.221, p＜0.001). Conclusion. This meta-analysis revealed significantly higher circulating IL-17 levels in patients with SLE and showed evidence of associations between IL17F CNVs and SLE. (J Rheum Dis 2020;27:37-44)
First record of Carebara oertzeni Forel, 1886 (Hymenoptera: Formicidae) from Albania

Purkart, A. , Jablonski, D. & Christophoryová, J.: First record of Carebara oertzeni Forel, 1886 (Hymenoptera: Formicidae) from Albania. Nat. Croat. Vol. 28, No. 1. , 173-176, Zagreb, 2019. The first record of the rare ant Carebara oertzeni Forel, 1886 from Albania is reported. Two workers of C. oertzeni were discovered in the south-eastern part of the country, near the village of Benjë-Novoselë. So far, it is the northernmost known distribution of this very rarely collected species, the sole representative of its genus in Europe, whose previous records all come from Greece and Turkey. In addition, we also found a specimen determined as the Proceratium melinum Roger, 1860 worker ant in the same soil sample.
Pourquoi et en quoi la créativité a-t-elle sa place en classe de langue(s)?

Les politiques educatives 1 et la recherche 2 semblent se rencontrer sur une competence a developper en enseignement-apprentissage : la creativite, associee a l'innovation dont elle est le moteur. Cependant, les interets divergent et les resultats des etudes egalement, mettant cette notion en question. Le developpement utilitariste de la creativite des individus a des fins de meilleure performance s'oppose a des approches humanistes qui mettent le bien-etre au coeur des enseignements-apprentissages. Quels processus sont a l'oeuvre dans une demarche creative ? De quelle creativite parlons-nous en didactique des langues ? Pourquoi et en quoi ces processus creatifs auraient, d'apres les etudes qui les plebiscitent, toute leur place dans le contexte scolaire, et a fortiori pour la pratique des langues Le concept de creativite, loin de la logique binaire traditionnellement ancree dans le systeme educatif, s'ancre dans un paradigme de la complexite a l'image de nos societes actuelles. La creativite permet des associations d'idees nouvelles ; elle relie ce qui a priori ne l'etait pas (Larsen-Freeman, 2013). Sa nature s'apparente a celle des langues vivantes, comme nous le verrons ci-apres. Dans cette publication, nous nous appuyons notamment sur les apports des neurosciences a la didactique des langues (Sambanis, 2013 ; Sofia, 2016 ; Spitzer, 2002) et en particulier, des neurosciences affectives et sociales (Damasio, 2003 ; Immodino-Yang et Damasio, 2007) et de la neurophenomenologie (Varela, 1996 ; Thirioux et Berthoz, 2010 ; Gallhager, 2007), pour comprendre les leviers potentiels de la creativite dans les processus d'apprentissage des langues. Nous faisons ainsi le lien entre les langues enseignees a l'ecole et parlees dans les familles, et les processus creatifs que la psychologie (Lubart, 2003) relie aux competences cognitives. Nous nous concentrons donc sur les ressources propres a chacun : les processus dynamiques et corporels au coeur l'apprentissage des langues, qu'il nous semble necessaire, au vu des recentes etudes, de solliciter davantage. A. La creativite : une notion a definir La creativite, qui fait l'objet de reflexions depuis des siecles, s'est particulierement revelee en pedagogie dans les annees 1970 (Beaudot, 1976 ; Jaoui, 1979). Au 21 e siecle, c'est une notion toujours a la mode, voire meme omnipresente dans des champs extremement varies (Bonnardel, 2006, p.13). Certaines caracteristiques qui la determinent semblent etre admises dans toutes les disciplines, telles la nouveaute ou l'originalite, la propension a la prise de risques, la pensee non lineaire ou la reflexion divergente (c'est-a-dire la capacite a associer differentes idees, a trouver des 1 Cf. Nouveau socle commun, 2016, p.2, p.6, p.7. 2 Cf. Les nombreux colloques autour de la creativite en pedagogie et des ouvrages recents tels celui de Capron Puozzo (2016).
Refinement of prespecified cutoff for genomic loss of heterozygosity (LOH) in ARIEL2 part 1: A phase II study of rucaparib in patients (pts) with high grade ovarian carcinoma (HGOC).

5540Background: ARIEL2 (NCT01891344) prospectively evaluated a tumor-based next-generation sequencing (NGS) LOH assay and novel algorithm to predict sensitivity to rucaparib based on BRCAmutstatus and degree of genomic LOH. Methods: Pts with measurable, platinum-sensitive HGOC were classified as BRCAmut, BRCAwt/LOHhigh (BRCA-like), or BRCAwt/LOHlow by NGS analysis of tumor tissue DNA. The primary objective of this analysis was to compare progression-free survival (PFS) of BRCAmut vs LOHhigh and LOHlow tumors. A planned post hoc analysis identified a refined genomic LOH cutoff to differentiate PFS of pts with LOHhigh vs LOHlowtumors. Results: ARIEL2 part 1 completed enrollment in December 2014; the data cutoff date was January 18, 2016. In 204 treated pts, median age was 65 years; median number of prior regimens was 1. Efficacy data are shown in the Table. The confirmed radiologic objective response rate (rORR) for germline (n=20) and somatic (n=20) BRCAmut pts was 85% and 75%, respectively. Refinement of .
PEDAGOGICAL PRACTICES OF LANGUAGES OTHER THAN ENGLISH TEACHERS: A CASE STUDY OF A MALAYSIAN PRIVATE UNIVERSITY

Purpose - Internationalization of education has made it important to have not only a command of English as a global language, but also of Languages Other Than English (LOTEs), which can be a second, national or heritage language. This narrative inquiry explored LOTE teachers’ perspectives on their use of English and other pedagogical practices for teaching LOTE to international students. Methodology - Narratives of three language teachers from different linguistic and cultural backgrounds, teaching French, Korean and Mandarin at a private university in Malaysia were recorded. Their discussion addressed key issues in teaching LOTE such as teaching strategies, use of technology and the importance of using English for teaching LOTEs. Data was analysed using Nvivo, applying Saldana’s (2016) coding technique, consisting of structural, descriptive and values coding. 48 codes emerged during the first cycle coding, which were placed under nine categories in the second and final coding process. Findings - Data revealed that for achieving practical outcomes, technologically integrated teaching is an alternative to traditional teaching practices. Further, teachers’ narratives also showed the importance of English in LOTE teaching, owing to the internationalization of education. Significance – The study explored LOTE pedagogy through the narratives of teachers, who are key stakeholders. The findings will help LOTE teachers reflect on their own teaching practices, and familiarize them with current pedagogy, including technology integration. They would also be useful in other contexts where LOTE is offered as a foreign language.
The dynamic interaction of coronary circulation, left ventricle and aortic valve during exercise

2 DEDICATION . 4 ACKNOWLEDGEMENTS . 5 CHAPTER 1: BACKGROUND . 10 1.1 OVERVIEW OF AORTIC STENOSIS. 11 1.1.1 The Epidemic of Valvular Heart Disease . 11 1.1.2 Pathophysiology . 11 1.1.3 Therapeutic Targets in Aortic Stenosis . 14 1.2 CORONARY PHYSIOLOGY . 15 1.2. 1 Setting the Scene. 15 1.2. 2 Assessment of pressure and flow: Mean Indices. 16 1.2. 3 Moving beyond means: Wave Intensity Analysis . 19 1.2. 4 Coronary Blood Flow during Exercise . 24 1.2. 5 Coronary Flow in Aortic Stenosis. 25 1.3 CORONARY MICROVASCULAR DISEASE . 27 1.4 REFINING THE ASSESSMENT OF AORTIC STENOSIS . 30 1.4. 1 Traditional grading of Aortic Stenosis . 30 1.4. 2 Concept of combined after load . 31 1.4. 3 Assessment of Left Ventricular Function in Aortic Stenosis . 33 1.4. 4 Rationale for studying AS during exercise . 34 1.5 IMPROVING OUR UNDERSTANDING OF AORTIC STENOSIS. 36 1.5. 1 Why Is This Important? 36 1.5. 2 Aortic Stenosis: Drawing Parallels with Coronary artery Disease . 37 1.6 AIMS AND OBJECTIVES . 38 CHAPTER 2. METHODS . 41 2.
Bone loss after liver transplantation : A randomized, double-blind, placebo- controlled trial

Background: Clinically important rapid bone loss occurs within 3 to 6 months after liver transplantation and may be associated with osteoporotic fractures. Objective: To determine whether bisphosphonate treatment with zoledronic acid reduces transplant-related bone loss more than placebo in adults having liver transplantation for chronic liver disease. Design: 12-month randomized, double-blind, placebo-controlled trial. Setting: 2 large liver transplantation centers in Australia. Patients: 62 adults having liver transplantation for chronic liver disease. Interventions: Infusions of zoledronic acid, 4 mg (n = 32), or saline (n = 30) were given within 7 days of transplantation and again at months 1, 3, 6, and 9 after transplantation. All patients received supplementation with calcium carbonate, 600 mg/d, and ergocalciferol, 1000 U/d. Measurements: The primary outcome was bone mineral density (BMD) measured by dual x-ray absorptiometry before transplantation and 3, 6, and 12 months later. Secondary outcomes included bone turnover markers that were measured before transplantation and 1, 3, 6, 9, and 12 months later. Results: There were statistically significant interactions between treatment effects and time for BMD measurements at the lumbar spine (P = 0.002), femoral neck (P = 0.001), and total hip (P < 0.001). Differences in acute bone loss 3 months after transplantation favored zoledronic acid over placebo. Differences between groups in percentage change from baseline adjusted for baseline weight and serum parathyroid hormone (PTH) level were 4.0% (95% CI, 1.1% to 7.0%) for the lumbar spine, 4.7% (CI, 1.9% to 7.6%) for the femoral neck, and 3.8% (CI, 1.7% to 6.0%) for the total hip. At 12 months after transplantation, the difference in percentage change from baseline between the 2 groups adjusted for baseline weight and serum PTH level was 1.1% (CI, -2.1% to 4.4%) for the lumbar spine, 2.7% (CI, 0.0% to 5.4%) for the femoral neck, and 2.4% (CI, 0.1% to 4.7%) for the total hip. Treatment with zoledronic acid induced temporary secondary hyperparathyroidism and postinfusion hypocalcemia statistically significantly more often than did placebo. Limitations: The trial was not powered to assess fractures, and 10 of 62 (16%) patients were not included in adjusted analyses because of missing weight or serum PTH measurements. Conclusion: Treatment with zoledronic acid can prevent bone loss within the first year after liver transplantation.