Miracle-dz/UniFAR-FTUs huggingface dataset:
Bankruptcy prediction with least squares support vector machine classifiers

Classification algorithms like linear discriminant analysis and logistic regression are popular linear techniques for modelling and predicting corporate distress. These techniques aim at finding an optimal linear combination of explanatory input variables, such as, e.g., solvency and liquidity ratios, in order to analyse, model and predict corporate default risk. Recently, performant kernel based nonlinear classification techniques, like support vector machines, least squares support vector machines and kernel fisher discriminant analysis, have been developed. Basically, these methods map the inputs first in a nonlinear way to a high dimensional kernel-induced feature space, in which a linear classifier is constructed in the second step. Practical expressions are obtained in the so-called dual space by application of Mercer's theorem. In this paper, we explain the relations between linear and nonlinear kernel based classification and illustrate their performance on predicting bankruptcy of mid-cap firms in Belgium and the Netherlands.
Clinical features and evolution of organ dysfunctions in sepsis.

UNLABELLED In sepsis, the systemic inflammatory response is adapted to the etiologic agent and the increase in the level of mediators is associated with organ dysfunction. Currently, a rapid assessment of patient ability to develop an adequate immune response is not possible, the response mechanisms being similar in the context of different etiological agents. AIM To find statistical arguments for the evolution of laboratory parameters in sepsis patients. MATERIAL AND METHODS This retrospective study included 90 patients diagnosed with sepsis. The clinical, etiological, and laboratory data, and Carmeli and APACHE II prognostic scores were analyzed. The data were processed using SPSS version 16.0. RESULTS The causative agents was identified in 16 cases; organ involvement and systemic response varied, and no statistical correlations were found between the inflammatory syndrome parameters and Carmeli or APACHE II prognostic scores or identification of the causative agent. CONCLUSIONS Statistical correlations were found between maximum blood glucose levels and the presence of organ dysfunction in the studied sepsis patients. No correlations were found between sepsis severity and the presence of anemia or thrombocytopenia, or between fever syndrome and inflammatory syndrome.
Novo‐G#: a multidimensional torus‐based reconfigurable cluster for molecular dynamics

Molecular dynamics (MD) is a large‐scale, communication‐intensive problem that has been the subject of high‐performance computing research and acceleration for years. Not surprisingly, the most success in accelerating MD comes from specialized systems such as the Anton machine. In this paper, we describe Novo‐G# (novo‐jee‐sharp), a multi‐node reconfigurable system designed for the acceleration of communication‐intensive scientific problems in general, and MD in particular. This system provides a high‐bandwidth, low‐latency 3D torus network to allow direct communication between kernels running on multiple field‐programmable gate arrays. We also present a performance model for Novo‐G# running the 3D Fast Fourier Transform (FFT) kernel that forms the core of MD simulations. We validate the model against published Anton performance data and through initial hardware experiments on Novo‐G#. Finally, through simulation studies, we show that this system at scale performs better than specialized systems like Anton and outperforms established CPU‐based clusters like Blue Gene/Q by an order of magnitude for the 3D FFT kernel, with greater flexibility and lower costs. Copyright © 2015 John Wiley & Sons, Ltd.
Black-pigmented Bacteroides from clinically characterized periodontal sites.

Gingival sites were clinically evaluated on the basis of gingival color and contour, pocket depth, bleeding upon probing and peercent bone loss as measured radiographically. Using anaerobic techniques, subgingival plaque collected from these sites was examined for the presence of the black-pigmented Bacteroides (BPB). The BPB were identified by biochemical testing and Gram stain morphology. With one exception, only saccharolytic strains (B. melaninogenicus) were found at normal and gingivitis sites, while these and asaccharolytic strains (B. asaccharolyticus) were found at sites exhibiting bone loss.
Changes of β‐amyloid precursor protein splice patterns in brain cell aggregate cultures

The splice pattern of β‐amyloid precursor protein (β‐APP) has been studied in a variety of neuronal and glial cells and in brain cell aggregate cultures by the polymerase chain reaction (PCR). The brain‐typical pattern, in which β‐APP695 is the dominant form, has been found only in aggregate cultures but not in any of the other cell types including neuronal cell lines. Selective elimination of glial cells from aggregates resulted in increased quantities of β‐APP695, whereas removal of neurons led to a reduction of β‐APP695 and to an elevation of β‐APP751 and β‐APP770. This shift of splice pattern was not observed in cocultures of the neuronal cell line PC 12 with primary astrocytes combined in a variety of cellular ratios. Blood serum, which is an essential component of these cultures, tested on aggregates, did not reduce the amount of β‐APP695 or have any marked effects on splice patterns generally. From these results it is concluded that investigations on brain‐typical splicing of β‐APP require primary neurons. Neuronal cell lines may be no suitable model systems. Splicing events favoring production of β‐APP695 may mark an important, very early step of amyloid formation in the brain. © 1994 Wiley‐Liss, Inc.
A Comparison of the Performance of Different Multiline Transmit Setups for Fast Volumetric Cardiac Ultrasound

It was previously demonstrated in 2-D echocardiography that a proper multiline transmit (MLT) implementation can be used to increase frame rate while preserving image quality. Initial findings for extending MLT to 3-D showed that it might address the low spatiotemporal resolution of current volumetric ultrasound systems. However, to date, it remains unclear how much transmit/receive parallelization would be possible using a 3-D MLT system. Therefore, the aim of this paper was to contrast different MLT setups for 3-D imaging by computer simulation in order to determine an optimal tradeoff between the amount of parallelization of an MLT system and the corresponding signal-to-noise ratio of the resulting images. Hereto, the image quality of several MLT setups was estimated by quantifying their crosstalk energy level. The results showed that for the tested setups, 4MLT broad beams and 9MLT narrow beams with Tukey (α = 0.5) apodization in transmit and receive give the highest frame rate gain while maintaining an acceptable interbeam interference level. Moreover, although 16MLT narrow beams with Tukey/Tukey (α = 0.5) apodization did show more pronounced interbeam interference, its gain in frame rate might outweigh its predicted loss in image quality. As such both 9MLT and 16MLT narrow beams were tested experimentally. For both systems, four receive lines were reconstructed from each transmit beam. The contrast-to-noise ratio of these imaging strategies was quantified and compared with the image quality obtained with line-by-line scanning. Despite some expected loss in image quality, the resulting images of the parallelized systems were very competitive to the benchmark, while speeding up the acquisition process by a factor of 36 and 64, respectively.
Compression experiments on term-document index

The increase in the size of the data used in natural language processing activities brings with it time and space constraints. Thus, it is important to both store and access data efficiently. This study includes experiments for storing the term-document index, which will be used in a natural language processing project, effectively in memory. For this purpose, the indexed data is compressed using Run-Length coding and then Huffman coding algorithm. Compression experiments have been conducted with new versions of Huffman Coding which are arranged in a structure suitable for indexing data used in the study. The results were compared with the results of commonly used compression tools and the results turned out to be successful.
Photochemical Products in Urban Mixtures Enhance Inflammatory Responses in Lung Cells

Complex urban air mixtures that realistically mimic urban smog can be generated for investigating adverse health effects. “Smog chambers” have been used for over 30 yr to conduct experiments for developing and testing photochemical models that predict ambient ozone (O3) concentrations and aerosol chemistry. These chambers were used to generate photochemical and nonirradiated systems, which were interfaced with an in vitro exposure system to compare the inflammatory effects of complex air pollutant mixtures with and without sunlight-driven chemistry. These are preliminary experiments in a new project to study the health effects of particulate matter and associated gaseous copollutants. Briefly, two matched outdoor chambers capable of using real sunlight were utilized to generate two test atmospheres for simultaneous exposures to cultured lung cells. One chamber was used to produce a photochemically active system, which ran from sunrise to sunset, producing O3 and the associated secondary products. A few hours after sunset, NO was added to titrate and remove completely the O3, forming NO2. In the second chamber, an equal amount of NO2 and the same amount of the 55-component hydrocarbon mixture used to setup the photochemical system in the first side were injected. A549 cells, from an alveolar type II-like cell line grown on membranous support, were exposed to the photochemical mixture or the “original” NO2/hydrocarbon mixture for 5 h and analyzed for inflammatory response (IL-8 mRNA levels) 4 h postexposure. In addition, a variation of this experiment was conducted to compare the photochemical system producing O3 and NO2, with a simple mixture of only the O3 and NO2. Our data suggest that the photochemically altered mixtures that produced secondary products induced about two- to threefold more IL-8 mRNA than the mixture of NO2 and hydrocarbons or O3. These results indicate that secondary products generated through the photochemical reactions of NOx and hydrocarbons may significantly contribute to the inflammatory responses induced by exposure to urban smog. From previous experience with relevant experiments, we know that many of these gaseous organic products would contribute to the formation of significant secondary organic particle mass in the presence of seed particles (including road dust or combustion products). In the absence of such particles, these gaseous products remained mostly as gases. These experiments show that photochemically produced gaseous products do influence the toxic responses of the cells in the absence of particles.
Low Testosterone—An Important Predictor of Low Mineral Bone Density in Young Men—Our Own Experience and a Review of Literature

Urologists and reproductive endocrinologists have become the first contact physicians for young men of reproductive age and have the unique opportunity to positively affect men’s health and quality of life. Growing evidence indicates that a significant proportion of men presenting with infertility or sexual dysfunction are hypogonadal. One hundred ninety nine men were enrolled in our center, and mean total testosterone was = 122, 57%), osteopenia (n = 69, 39%) and osteoporosis (n = 8, 4%). There were no differences in the mean age (p 0.64), height (p 0.99) and weight (p 0.02). Our results indicate that hypogonadism is one of the main risk factors for osteopenia and osteoporosis which can be found in 8% of hypogonadal men younger than 50 years of age. Testosterone replacement therapy may be indicated in most men with hypogonadism and low bone mineral density (BMD); however the benefits of testosterone treatment in eugonadal men are unproven. Selective estradiol and androgen receptor modulators expand our treatment modalities in men of reproductive age when suppression of gonadotropins may interfere with reproductive plans. Early detection of hypogonadism and osteoporosis may lower the risk of hip and vertebral fractures in some men. Further prospective RCTs are needed to prove cost-effectiveness of detection and the best treatment of osteoporosis in hypogonadal men of reproductive age. Urologists have the opportunity to be at the forefront of greater awareness of this clinical problem due to their frequent contact with this population of patients.
Racetrack Memory-Based Nonvolatile Storage Elements for Multicontext FPGAs

A multicontext field-programmable gate array (FPGA) is a solution to achieve fast run-time reconfiguration. However, SRAM-based multicontext FPGAs still suffer from high leakage power during sleep, slow power-ON speed, and excessive large memory area. Racetrack memory is one of the most promising resistive nonvolatile memories, with the advantages of low power, high density, and high speed. In this paper, we propose two racetrack memory-based nonvolatile storage elements (NVSEs) for multicontext FPGAs. One is the shifting-based NVSE (type-1) with the advantages of high density and low power. The other one is the address-based NVSE (type-2) with the advantages of high context switching speed and low context switching power. The versatile place and route simulation results show that the type-1 NVSE-based eight-context FPGA reduces the area, critical path delay, and the power of the SRAM-based eight-context FPGA by more than 68.1%, 22.8%, and 13%, respectively. The proposed type-2 NVSE-based FPGAs allow the contexts to be switched 4.46 times faster than the type-1 NVSE-based FPGAs. Both designs improve the FPGA power-ON speed by more than a million times. Compared with the conventional racetrack memory-based lookup table (LUT), the proposed racetrack memory-based LUT may reduce the total power by more than 25%.
Altogether now: Activating interdependent self-construal induces hypermotor resonance

Nonconscious mimicry (NCM) has been widely studied but the mechanisms underlying it remain unspecified. One possibility is that NCM is mediated by motor resonance (MR). If so, factors that moderate NCM may affect MR. Priming interdependent self-construal (InterSC) increases NCM. We measured MR in a cued-response task using electromyography (EMG) while participants squeezed a rubber ball hard or softly in response to colored words. Words were superimposed on videos depicting hard or soft squeezes. Words primed InterSC or independent self-construal (IndSC). When observed squeezes were incongruent with word color, reaction time (RT) slowed and EMG activity was modulated. These effects were greater for InterSC primes than IndSC primes. Participants who failed to notice any difference in the actions in the videos also showed the effect. Activating InterSC causes MR processes to become hypersensitive to observed actions, even in the absence of awareness of what the action was.
Long-term follow-up after the first episode of acute alcoholic pancreatitis: time course and risk factors for recurrence.

BACKGROUND Owing to the current lack of long-term follow-up data on the recurrence of alcohol-induced acute pancreatitis (AP), we studied the pattern of recurrence and determined the characteristics of the disease to predict the recurrence. METHODS Between 1972 and 1991, 2678 AP episodes were detected; 1555 were induced by alcohol, and 591 of them were the first episode. During the first alcohol-induced AP 29 patients died and were excluded from further analysis. Of the 562 included, 503 were men, and 59 women. Admission serum tests, severity index, development of complications, intensive care unit and hospital stay, and need for surgery were assessed. Case records were studied. The national database was used to detect admissions to other hospitals. RESULTS Overall, 260 (46%) developed recurrent disease. Of the first relapses, 80% developed during 4 years. The recurrence rate has not changed with time. Age less than 45 years increased the risk (odds ratio (OR) = 2.42; 95% confidence interval (CI), 1.30-4.50). The risk factors of the first alcohol-induced AP associated with the development of multi-recurring pancreatitis are age <45 years (OR, 2.42; 95% CI, 1.59-13.0), 0-2 positive Glasgow criteria (OR, 2.45; 95% CI, 1.16-5.19), and arterial oxygen tension >60 mmHg (OR, 9.90; 95% CI, 1.32-74.3). CONCLUSIONS Fewer than half of the patients develop recurrent alcohol-induced AP. Younger patients are at the highest risk of recurrence. Those whose first alcohol-induced pancreatitis episode was not severe are at a higher risk of developing multi-recurring pancreatitis.
Evaluation of self-reported measures for prediction of periodontitis in a sample of Brazilians.

BACKGROUND Questionnaires including self-reported measures have become effective as a means of accessing many diseases. The aim of the present study is to evaluate the performance of a set of self-reported periodontal measures on estimating the prevalence of periodontitis. METHODS The sample comprised 284 individuals, aged 18 to 60 years, from Belo Horizonte, Brazil. Full-mouth periodontal examinations were performed and periodontal parameters were recorded. Periodontitis was categorized as no or mild, moderate, and severe. Each participant answered 18 questions covering sociodemographic variables, known risk factors, and self-reported periodontal measures. Questions were globally tested through logistic regression analysis. RESULTS The complete final model for moderate periodontitis included age, dental flossing, and gum disease (sensitivity = 23.1%; specificity = 98%; area under the receiver operating characteristic curve = 75.4%). The complete final model for severe periodontitis included all previously cited variables in addition to the number of teeth (sensitivity = 36.4%; specificity = 96.9%; area under the receiver operating characteristic curve = 85.3%). CONCLUSIONS Self-reported periodontal measures showed a moderate predictive value for periodontitis prevalence. The use of these measures could be a good strategy in investigating prevalence of periodontal disease.
Automated Packet Classification and Layer Identification of Network Packets a Review

Traffic classification is an automated process which categorizes computer network traffic according to various into a number of traffic classes. In this paper we are comparing different traffic classification methods and also presents an automated packet classification and layer identification to improve classification performance when few training data is available. In this we are grouping the similar flows and classifying it by using a classifier combination framework. We are aggregating naive Bayes (NB) predictions of the correlated flows. In this we are finding the denial of service (DOS) attack and also we are identifying which all applications are running in the systems which connected in that network. We are identifying the applications based on their port number.
Evidence for intermuscle difference in postactivation potentiation in the human triceps surae: A mechanomyographic study

This study compared the postactivation potentiation of the medial gastrocnemius (MG) and soleus muscles by using mechanomyography (MMG). Twitch responses were evoked by stimulating the posterior tibial nerve with supramaximal intensity before and after a 10‐s maximal voluntary plantar flexion, and potentiation of each muscle was evaluated by peak‐to‐peak amplitude of the MMG signal. The MG showed greater potentiation than the soleus, reflecting the reported fiber type composition of these muscles. This result points to the possibility that one can delineate contrasting responses of synergist muscles to postactivation potentiation by this method. Muscle Nerve 39: 703–706, 2009
A subunit of coatomer protein complex offers a novel tumor-specific target through a surprising mechanism

COPI, a coatomer protein complex of secretory vesicles, is involved in Golgi and endoplasmic reticulum traffic and in early endosome maturation. The loss of COPI results in the fragmentation of Golgi, accumulation of immature autophagosomes, inhibition of autophagy, and cell death. Since COPI is required by all cells, it would appear an unlikely target for cancer treatment. However, our recent function-based genomic screen unexpectedly identified a specific COPI subunit, ζ1, as a cancer-specific target. The existing cancer drugs kill only proliferating but not growth-arrested tumor cells, but the depletion of ζ1 induces cell death in both dividing and nondividing tumor cells, while sparing normal cells. The mechanism of this remarkable tumor selectivity turned out to be surprising and heretofore unprecedented.
An example of a deterministic cellular automaton exhibiting linear-exponential convergence to the steady state

In a recent paper [arXiv:1506.06649 [nlin.CG]], we presented an example of a 3-state cellular automaton which exhibits behaviour analogous to degenerate hyperbolicity often observed in finite-dimensional dynamical systems. We also calculated densities of 0, 1 and 2 after n iterations of this rule, using finite state machines to conjecture patterns present in preimage sets. Here, we re-derive the same formulae in a rigorous way, without resorting to any semi-empirical methods. This is done by analysing the behaviour of continuous clusters of symbols and by considering their interactions.
Marchiafava-Bignami disease

A 57-year-old man with a history of chronic alcoholism was evaluated for seizures. MRI showed severe diffuse atrophy of the corpus callosum (CC). Clinical examination revealed bimanual coordination difficulties, left ideomotor apraxia, and tactile anomia. The genu and the splenium had central cystic degeneration, with sparing of the peripheral layers. Tractography showed the lack of central white matter tracts, an “acquired callosotomy” (figure). The imaging findings were compatible with the chronic phase of Marchiafava-Bignami disease, a rare demyelinating disorder, primarily affecting the central CC layers, thought to be due to chronic alcohol consumption.1,2
Suicidal Behavior and Attitudes in Slovak and Turkish High School Students: A Cross-Cultural Investigation

Suicidal behavior and its variation across social contexts are of importance for the science of suicidology. Due to its special character controlled experimental studies on suicide are ruled out for ethical reasons. Cross-cultural studies may throw light on the etiology of both suicidal behavior and its cross-cultural variation. The present study compared suicidal behavior and attitudes in 423 Slovak and 541 Turkish high school students by means of a self-report questionnaire. The two groups reported similar percentages (Slovak = 36.4%; Turkish = 33.8%) of lifetime, past 12-months or current suicidal ideation but significantly more Turkish (12.2%) than Slovak (4.8%) students reported lifetime or past 12-months suicide attempts. Slovak adolescents displayed more liberal and permissive attitudes toward suicide, while those of Turkish adolescents were more rejecting. Turkish students rated themselves to be more religious and hence they believed to a greater extent that suicidal persons would be punished in a life after death than their Slovak peers. However, attitudes of Turkish students toward an imagined suicidal close friend were more accepting than the attitudes of Slovak students. Comparison of suicidal and nonsuicidal students revealed that those reporting suicidal ideation or attempts were more accepting of suicide and viewed suicide as a solution to a greater extent than the nonsuicidal ones. The results from this study suggest that cultural factors play a role in suicidal behavior, attitudes and reactions in a predicted direction.