Miracle-dz/UniFAR-FTUs huggingface dataset:
Studies on the group F antigen of lactobacilli: antigenicity and serological specificity of teichoic acid preparations.

SUMMARY: The membrane glycerol teichoic acid of group F lactobacilli (e.g. Lactobacillus fermenti) has been identified as the group antigen. The most active preparations, obtained by phenol extraction, reacted readily with antisera and were antigenic when injected into rabbits with Freund's adjuvant. The products obtained by the action of trichloracetic acid were separable into a high molecular weight fraction, which reacted well with antiserum but was not a very effective antigen, and a low molecular weight fraction which was not antigenic and reacted weakly with group antisera. Specificity of the group antigen depends primarily on galactose with glucose being a minor contributor. However, the ability of galactose and glucose to inhibit the precipitin reaction differs considerably with different antisera. Teichoic acids from other strains of L. fermenti cross-reacted with the group antisera to varying extents but preparations from L. casei strains reacted only weakly.
Staphylococcus aureus bacteremia: the cost-effectiveness of long-term therapy associated with infectious diseases consultation.

OBJECTIVE To investigate the cost-effectiveness of long-term therapy for Staphylococcus aureus bacteremia and to determine if an infectious diseases consultation affected the duration of therapy. METHODS A decision analysis was performed based on data from the literature. To determine if consultation was related to therapy duration, a retrospective cohort study was performed using tightly matched pairs. RESULTS The excess cost per life saved by long-term antibiotics was $500,000. The excess cost per life-year saved was $18,000. Nine pairs were matched. Patients who received consultation were more likely to receive long-term therapy than controls (median 41 days vs 15 days for controls, P = .04). CONCLUSIONS The estimated cost per life-year saved by long-term therapy was similar to other accepted medical interventions. Infectious diseases consultation can encourage prolonged duration of antibiotic therapy for S aureus bacteremia.
Exploiting Cryptocurrency Miners with OISNT Techniques

Collection of intelligence is one of the key elements to organize more sophisticated methods of attacks. Open Source Intelligence (OSINT) is a technique used by attackers for reconnaissance purposes to gather information about specific targets. The accessibility to critical information about emerging systems through OSINT leads exposure of vulnerabilities and exploitation of these vulnerabilities to form widespread attack. Blockchain is one of the emerging technologies that exposed the use of crypto currencies such as Bitcoin and Ethereum. This research paper explains the use of OSINT to gather critical information about cryptocurrency miners such as Bitcoin Antminer and Ethereum Claymore and expose the vulnerabilities to exploit the configuration file of the miner manager. The research outcomes expose the vulnerability of the existing crypto currencies and use of OSINT for detection and analysis of cyber-threat in crypto currency market.
Relationship between Urinary Podocytes and Kidney Diseases

Podocyte loss is an important component of disease progression in glomerular diseases. To some extent, the loss of podocytes can predict the degree of damage and the advancement of renal disease. Detecting the loss of podocytes in the urine could be a valuable, noninvasive method for obtaining information about the activity of the disease or the disease type, allowing the early diagnosis of glomerular diseases. One of the most robust markers that has been successfully used for urinary podocyte diagnostics is podocalyxin (PDX). PDX is a sialoprotein that is expressed on podocytes and on a variety of nonrenal cells as well as on glomerular endothelial and parietal epithelial cells. Therefore, podocyte loss can be detected by the amount of PDX in the urine. The relationship between urinary podocytes and renal diseases is supported by the detection of podocytes in patients with immunoglobulin A (IgA) nephropathy, Henoch–Schönlein purpura nephritis, lupus nephritis, diabetic nephropathy, and focal segmental glomerulosclerosis. The use of technology for detecting podocytes in the urine would have broad implications for the evaluation of disease activity, the degree of dedifferentiation, and the possibility of regeneration.
A Study on Consumer Decision towards Purchase of Organic Food Products: A Case Study of Delhi

Traditional marketing concept imparts that the products were made to be sold to the customers, whereas the modern marketing practices emphasize on identifying the needs of the customers and then starts the manufacturing process. However, the current marketing concepts extend towards satisfying the needs of the customers without causing any environmental degradation. Now-a-days customers are expected to minimise environmental degradation through their consumption habits. Our study has selected Organic food products for studying the decision of consumers towards their consuming habits. At the first stage, we conducted an in-depth interview of the manufacturer of Organic food products in Delhi, and later on we conducted a survey for 45 respondents across different Organic food products stores in Delhi. The results revealed various facilitators and barriers affecting the purchase of Organic food products. In addition, the level of awareness of consumers was analysed through this survey.
Efficacy of S-1 in Patients with Castration-Resistant Prostate Cancer: A Phase II Study

Objectives: This study was conducted to evaluate the efficacy and safety of S-1, an oral fluoropyrimidine derivative, in Japanese patients with castration-resistant prostate cancer (CRPC). The primary endpoint was prostate-specific antigen (PSA) response. Methods: In this open-label phase II study, S-1 was started at a dose of 80, 100 or 120 mg daily based on body surface area (BSA) for 28 days, followed by 14 days of rest. Patients with histological proof of prostate cancer refractory to hormonal therapies were eligible. Patients who received prior chemotherapy were excluded. All patients provided written informed consent. To observe 20% confirmed PSA response, 33 assessable patients were needed. Treatment was continued until disease progression or the development of intolerable toxicity. Results: A total of 35 eligible patients were enrolled. The median number of treatment cycles was 3. PSA response was observed in 8 patients (22.9%, 90% CI 11.9–37.5), including 3 in which (8.6%) the PSA level normalized. The median overall survival was 25.4 months. The most common treatment-related grade 3 toxicity was anorexia (14.3%). There was no death during the study. Conclusion: S-1 monotherapy is active against castration-resistant prostate cancer and has acceptable toxicity.
Improved architecture of the feedforward neural network for image recognition

Recently, the researchers have been focusing on the convolutional neural network due to its high reliability in image recognition. It is proposed that the feedforward neural network could compete equivalently with the convolutional neural network? In this paper, we have explored the possibility and proposed a feedforward neural network, namely the scaled conjugate gradient backpropagation feedforward neural network with random connections (SCGBP-FNN-RC) to learn big data through recognizing images from the widely known MNIST dataset which is applied with affine and elastic distortions. Based on our findings, SCGBP-FNN-RC has managed to achieve a state-of-the-art accuracy of 99.54 %. The proposed networks are then evaluated based on various parameters, e.g. the neuron size, connections and the Κ parameter.
Effects of antipsychotic medications on psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study.

OBJECTIVE This study examined the relative effects of the second-generation antipsychotic drugs and an older representative agent on psychosocial functioning in patients with chronic schizophrenia. METHOD Consenting patients were enrolled in the NIMH Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project. In phase 1, patients were randomly assigned to receive olanzapine, perphenazine, quetiapine, risperidone, or ziprasidone for up to 18 months. Clozapine was included for patients who chose this pathway after discontinuing phase 1 due to inefficacy; all other patients received another second-generation antipsychotic. Psychosocial functioning was assessed using the Quality of Life Scale. RESULTS Psychosocial functioning modestly improved for the one-third of phase 1 patients who reached the primary Quality of Life Scale analysis endpoint of 12 months (average effect size 0.19 SD units). Although for several of the drugs individually there were significant changes from baseline, overall there were no significant differences between the different agents. Results were similar at 6 and 18 months. There were no significant differences among the treatment groups in the amount of change in the Quality of Life Scale total score or subscale scores at 6, 12, or 18 months. Patients treated with clozapine in the efficacy pathway made comparable gains. Early treatment discontinuations, especially among patients most impaired at baseline, limited the ability to achieve more substantial functional gains. CONCLUSIONS All antipsychotic treatment groups in all phases made modest improvements in psychosocial functioning. There were no differences among them after 6, 12, or 18 months. More substantial improvements would likely require more intensive adjunctive psychosocial rehabilitation interventions.
Imprinting the Gnas locus

Gnas is an enigmatic and rather complex imprinted gene locus. A single transcription unit encodes three, and possibly more, distinct proteins. These are determined by overlapping transcripts from alternative promoters with different patterns of imprinting. The canonical Gnas transcript codes for Gsα, a highly conserved signalling protein and an essential intermediate in growth, differentiation and homeostatic pathways. Monoallelic expression of Gnas is highly tissue-restricted. The alternative transcripts encode XLαs, an unusual variant of Gsα, and the chromogranin-like protein Nesp55. These transcripts are expressed specifically from the paternal and maternal chromosomes, respectively. Their existence in the Gnas locus might imply functional connections amongst them or with Gsα. In this review, we consider how imprinting of Gnas was discovered, the phenotypic consequences of mutations in each of the gene products, both in the mouse and human, and provide some conjectures to explain why this elaborate imprinted locus has evolved in this manner in mammals.
Review: Brain—immune communication psychoneuroimmunology of multiple sclerosis

The central nervous system (CNS) and the immune system are two extremely complex and highly adaptive systems. In the face of a real or anticipated threat, be it physical (eg, infection) or psychological (eg, psychosocial stress) in nature, the two systems act in concert to provide optimal adaptation to the demanding internal or environmental conditions. During instances of well being, the communication between these two systems is well tuned and balanced. However, a disturbed crosstalk between the CNS and the immune system is thought to play a major role in a wide series of disorders characterized by a hyporesponsive or hyperresponsive immune system. In multiple sclerosis (MS), a chronic inflammatory and neurodegenerative disease, an excess of inflammatory processes seems to be a hallmark and there is growing evidence for a disturbed communication between the CNS and the immune system as a crucial pathogenic factor. While the exact mechanisms for these phenomena are still poorly understood, the young discipline of psychoneuroimmunology (PNI), which focuses on the mechanism underlying the brain to immune crosstalk, might offer some insights into the existing pathogenic mechanisms. Findings from the field of PNI might also help to gain a better understanding regarding the origin and course of MS clinical symptoms such as fatigue and depression.
An MCA/MR syndrome with hypocholesterolemia due to familial hypobetalipoproteinemia: Report of a second patient with Nguyen syndrome

[Nguyen et al. (2003); Am J Med Genet 121A: 109–112] reported a boy with severe hypocholesterolemia due to autosomal dominant hypobetalipoproteinemia (ADBHL) associated with severe growth retardation, mental deficiency, epicanthal folds, a short nose with low nasal bridge and anteverted nares and bilateral partial cutaneous syndactyly of toes 2 and 3. Many of these manifestations resembled those in a mild form of Smith–Lemli–Opitz syndrome (SLOS). We report on a 13‐year‐old boy with ADHBL, who manifested a SLOS‐like phenotype, including mental retardation and a characteristic face, similar to that of a patient reported by [Nguyen et al. (2003); Am J Med Genet 121A: 109–112]. Our patient supports the hypothesis by [Nguyen et al. (2003); Am J Med Genet 121A: 109–112] that ADHBL induced cholesterol deficiency has a significant effect on morphogenesis during embryogenesis, although additional genetic or environmental factors may be required to develop an SLOS‐like phenotype in individuals with ADHLB. This is a second case of Nguyen syndrome. © 2005 Wiley‐Liss, Inc.
Implementing Enhanced Early Childhood Development Package, Leveraging m-Health and Using a Task-Shifting Approach in Kenya

The WHO/UNICEF have recently disseminated the Care for Child Development curriculum for training community health workers (CHWs) to provide counseling on early childhood development to parents during routine home visits in low resource countries. We propose to integrate it with a ‘human-computer hybrid’ platform that functions as a 2-way SMS communication tool to engage parents on ECD issues and empower CHWs to provide psychosocial support on a more frequent basis. We will identify high risk, vulnerable families to augment in-person and mobile interface to further address mental health, community health promotion model and early childhood development. We will also identify three areas of growing concern which include engagement with male caregiver/s, high risk parents/mothers and deepening psychosocial support over mobile interface. Finally, we will address how our hybrid model integrates several ECD and MCMH approaches in oﬀering a unique community health promotion framework, health workforce and parental empowerment. Relevance to innovation. The proposed model of ECD delivery leverages on existing mobile technology to enhance eﬃciency and supervision of the delivery of ECD packages developed by WHO. It is a process innovation for public use that is aimed at improving neurodevelopmental outcomes for children and can be used in any low income setting with access to mobile technology and trained health personnel.
Desarrollo y evaluación de un sistema de teleoperación de robots basado en reconocimiento de gestos usando el sensor Kinect

En este Proyecto Fin de Carrera, se presenta un sistema de reconocimiento de gestos para teleoperar robots basado en el sensor Kinect. El proyecto se divide en dos partes, la primera relativa al diseno y evaluacion de un sistema de reconocimiento de gestos basado en el sensor Kinect; y la segunda, relativa a la teleoperacion de robots usando el sistema de reconocimiento de gestos desarrollado. En la primera parte, se enumeran las caracteristicas y limitaciones del sensor Kinect. Posteriormente, se analiza la deteccion de movimiento y se presenta la maquina de estados propuesta para detectar el movimiento de un gesto. A continuacion, se explican los posibles preprocesados de un esqueleto en 3 dimensiones para mejorar la deteccion de gestos y el algoritmo utilizado para la deteccion de gestos, el algoritmo de Alineamiento Temporal Dinamico (DTW). Por ultimo, se expone con detalle el software desarrollado de reconocimiento y evaluacion de gestos, el Evaluador de Gestos, y se realiza un analisis de varias evaluaciones realizadas con distintos perfiles de configuracion donde se extraen las conclusiones de acierto, fiabilidad y precision de cada configuracion. En la segunda parte, se expone el sistema de teleoperacion del robots y su integracion con el evaluador de gestos: este sistema controla el robot Lego Mindstorm mediante la deteccion de gestos o el reconocimiento de voz. Por ultimo, se exponen las conclusiones finales del proyecto.
Recovery of behavioral abnormalities after right hemisphere stroke

We studied recovery of function in 41 patients with right hemisphere stroke. Recovery was rapid for left neglect, prosopagnosia, anosognosia. and unilateral spatial neglect on drawing (USN). Recovery was slower for hcmianopia. hemiparesis, motor impersistence, and extinction. Rates of recovery were intermediate for constructional apraxia and dressing apraxia. Sex had no influence on the rate of recovery. Younger patients recovered from prosopagnosia more rapidly than older patients. Patients with smaller lesions recovered more quickly from anosognosia, USN, and hemiparcsis than patients with larger lesions. Patients with hemorrhages recovered more rapidly from constructional apraxia, neglect, and motor impersistence than patients with infarcts. Recovery of function and the factors influencing recovery can by studied systematically by life table methods.
Chromosomal aberrations and fetotoxic effects of atmospheric arsenic exposure in mice

Fetal chromosomal damage and toxicity were investigated in mice exposed to the atmospheric concentrations of 28.5 mg m−3, 2.9 mg m−3 and 0.26 mg m−3 of arsenic for 4 h per day on the 9th, 10th, 11th and 12th days of gestation. On the 18th day, the fetuses were removed, and the following parameters were examined: the number of dead fetuses, retardation in growth, osteogenesis and chromosomal aberrations in liver cells. It was found that exposure to As2O3 at 28.5 mg m−3 caused fetotoxic effects and chromosomal damage, while the two lower exposures produced no significant changes with the exception of a slight decrease (9.9 and 3.1%, respectively) in fetal weight.
Computing & Allied Engineering Domain in India with Reference to Private Universities: A Case Study of Bachelors Programs

Computing has been considered as important tools and technologies for information activities ranging from collection, selection, organization, processing, management, and dissemination of information. Computer Science including other allied fields becomes important for the creation of computation systems around the world. As the progress in the computing technology continues in the society, many universities around the world have started Computing and Information Technology related degrees. India is rising rapidly in terms of many things including economy and education. As a developing country, India is shining and growing rapidly in the education sector through its liberal higher education policies. India is considered as one of the important nations for the growth in Engineering education and skill development. India holds world largest higher educational institutions and about eight hundreds of them are degree awarding bodies. There are good numbers of Engineering programs mainly offered in the Engineering and Technological Colleges and Universities of different kinds. In recent past among the Higher educational Institutes in India Engineering programs have been started rapidly in private universities. This study provides a detailed overview of higher educational institutions in India emphasizing Engineering sectors. This study provides a strong focus on computing and information technology related programs available in private universities in India in Engineering segment.
An integrated framework for customer-oriented web design using QFD, Kano model and ANP

The aim of this article is to determine the most important elements in designing and founding a website which is one of the instances of new product development (NPD) in information technology (IT) surroundings. It has been used a three phased approach, which is related to Quality Function Deployment (QFD), Kano model and Analytical Network Process (ANP). This integrated process helps to define the necessary factors of the intended problem, improve them and deal with the priorities in problem structure by considering both intra and interrelationships due to their importance. Finally, the most critical subjects in a case of web-designing can be recognized.
Contrôle d'exécution pour robots mobiles autonomes: architecture, spécification et validation

Le travail presente dans le memoire traite des problemes lies au controle d'execution des actions des robots mobiles autonomes. Une premiere partie presente l'architecture de controle globale et la compare a d'autres approches. On decrit les niveaux hierarchiques qui la constituent et leurs roles dans le fonctionnement du systeme. Le niveau inferieur, compose d'un ensemble de modules, rassemble les fonctions de perception, de modelisation et d'action du systeme. La seconde partie presente le niveau executif. L'executif doit suivre l'execution des fonctions, resoudre les conflits entre modules, accomplir certaines actions reflexes et maintenir une information sur l'utilisation des ressources non partageables du robot. Il peut etre vu comme un ensemble d'automates, qui interagissent et changent d'etat selon les requetes qui arrivent du niveau superieur et les repliques qui proviennent des modules. La mise en oeuvre de l'executif utilise le systeme a base de regles KHEOPS. La compilation faite par KHEOPS permet, a partir d'un ensemble de variables d'entree et de sortie et des regles qui les relient, d'obtenir un arbre de decision equivalent et de profondeur connue, ce qui garantit un temps d'execution borne pour l'executif. La compilation permet aussi de garantir certaines proprietes logiques des automates mis en place. La troisieme partie presente les relations entre le niveau fonctionnel (modules et executif) et la couche immediatement superieure, le niveau tache. Ce niveau est base sur le systeme PRS, qui transforme des taches de haut niveau d'abstraction en procedures d'actions reconnues par le niveau fonctionnel et surveille leur execution. Le memoire presente une equivalence entre un sous-ensemble de PRS et les reseaux de Petri colores, ce qui permet de faire une verification du niveau tache quand l'equivalence existe. Enfin, on presente quelques res ultats de la mise en oeuvre experimentale de ces travaux avec le robot Hilare 2.
Time‐between‐events control charts for an exponentiated class of distributions of the renewal process

Time‐between‐events control charts are commonly used to monitor high‐quality processes and have several advantages over the ordinary control charts. In this article, we present some new control charts based on the renewal process, where a class of absolutely continuous exponentiated distributions is assumed for the time between events. This class includes the generalized exponential, generalized Rayleigh, and exponentiated Pareto distributions. Although we discuss the design structure for all the mentioned distributions, our main focus will be on the generalized exponential distribution due to its practical relevance and popularity. Since the generalized exponential distribution is a generalization of the traditional exponential distribution, the new control chart is more flexible than the existing exponential time‐between‐events charts. The control chart performance is evaluated in terms of some useful measures, including the average run length (ARL), the expected quadratic loss, continuous ranked probability, and the relative ARL. The effect of parameter estimation using the maximum likelihood and Bayesian methods on the ARL is also discussed in this article. The study also presents an illustrative example and 4 case studies to highlight the practical relevance of the proposal.