Miracle-dz/UniFAR-FTUs huggingface dataset:
Re-centring the curricular market : Pedagogic identities in IB Diploma programs in Australia

Bernstein’s last book (2000) laid the foundations for a theory of how curricular orientations projected pedagogic identities for both teachers and students. This paper will use his typology of curricular orientation and concept of pedagogic identity to understand the growing phenomenon of schools offering the International Baccalaureate Diploma as an alternative senior schooling curriculum in Australia. Such an internal curricular market takes the responsibility off the broader social order to politically negotiate and shape a singular curriculum for all citizens (as is notionally the case of the proposed national curriculum), and gives it to the individual to choose between the different curricular products on offer, matching both capacities and aspirations to the pedagogic identities projected by the curricular product. This ecology of neo-liberal choice, it is suggested , will highlight the discursive production of reputations and branding, expressed through ideal types of graduates and their dispositions, that is, the pedagogic identities invoked.
On MDS codes via Cauchy matrices

A special form of Cauchy matrix is used to obtain a tighter bound for the validity region of the maximum distance separable (MDS) conjecture and a new compact characterization of generalized Reed-Solomon codes. The latter is further used to obtain constructions and some existence results for long (2k, k) double-circulant MDS codes. >
Health, attitude to care and pattern of attendance among gypsy women-a general practice perspective.

BACKGROUND There is a lack of knowledge about health and attitude to care among gypsies. OBJECTIVES The aim of this study was to explore the reasons for and patterns of attendance among gypsy women in primary health care and to shed light on health problems of gypsies. METHODS Four gypsy women, frequently attending a primary health care centre, were interviewed in depth. Data were analysed according to grounded theory. Additional facts were received from record files. RESULTS AND CONCLUSIONS The gypsy women seldom approached the health centre alone but paid a visit together with relatives or friends. The women usually presented the same type of symptoms, often pain, headache and depression, and obtained the same type of diagnosis and treatment. The symptoms had an acute character and the women wanted immediate access. A collective pattern, a hierarchical order and a strict rule system characterized the gypsy life and coloured the relation to health and illness. Young women were especially vulnerable and could easily end up outside the collective and display symptoms.
Mechanical Testing of Hermetic Motor Systems

Following is a discussion of two testing procedures that can be performed on hermetic motors to ensure mechanical compatability with the compressor system. The first details a plug reversal procedure which utilizes forced refrigerant flow to maintain a predetermined motor temperature and to simulate the mechanical impingement of oil and gas flow onto the stator windings. The second test is useful for determining the magnitude of unbalanced magnetic forces in the motor at start greater than the compressor stiffness can absorb. Both tests are applicable to single and polyphase motors of all voltages utilized in across-the-line or increment (step) starting procedures.
High performance of fuzzy direct power control for PWM converters

This paper presents a new approach of direct power control (FLC-DPC) strategy for to three phase PWM converters. In this novel strategy the fuzzy logic control (FLC) has been used. The converter lookup table is based on fuzzy logic rules, using the instantaneous active and reactive power errors and the position of grid voltage vector. The basic idea of fuzzy rules synthesis is based on the knowledge of the instantaneous variation of active and reactive power flows to the grid. The main advantages of the improved approach of DPC strategy are that it is not necessary to use hysteresis comparators, smooth control of active and reactive power flows and maintaining the dc-bus voltage of the converter close to the reference value. The robustness of the FLC-DPC to sampling frequency variations, line inductance variations and tracking capability are also presented. Results have proven excellent performance, and verify the validity of the proposed DPC strategy which is much better than the classical direct power control strategies.
Cue Saliency in Faces as Assessed by the ‘Photofit’ Technique

The present study attempted to assess the relative salience of different parts of the human face through the manipulation of the features contained in the Photofit Kit. Subjects observed a face constructed from the kit before attempting to identify the same face in an array of alternatives. The alternatives differed from the target in only one feature and this was systematically varied within the array. Nose changes were least likely to be noticed, followed by mouth and eyes, with foreheads producing the lowest rate of error. This order of features held irrespective of the similarity of the distractors or whether judgements were made in the presence or in the absence of the target. The chin region produced different results depending upon the similarity of the distractors. The results are discussed in relation to earlier experiments in which Photofit and previous studies of cue saliency were used.
Thoracic radiotherapy does not prolong survival in patients with locally advanced, unresectable non-small cell lung cancer.

STUDY OBJECTIVE To compare the survival of patients with locally advanced non-small cell lung cancer treated with single-agent vindesine, thoracic radiotherapy, or both treatment modalities. DESIGN Randomized, prospective, phase III trial. SETTING Multi-institutional, university-based national cooperative oncology group. PATIENTS The study included 319 patients with locally advanced, unresectable non-small cell lung cancer who had no evidence of extrathoracic metastases. All patients were ambulatory and had measurable disease. Some patients could not have surgery because of coexisting medical conditions. INTERVENTION Patients were randomly assigned to receive vindesine, 3 mg/m2 body surface area weekly; standard thoracic radiotherapy, 60 Gy over 6 weeks; or both vindesine and thoracic radiotherapy. Vindesine was administered for 6 weeks and then every other week to patients who had no disease progression. Patients who developed progressive disease while receiving vindesine or radiotherapy alone were crossed over to radiotherapy or vindesine, respectively. Response assessment took place at week 6. RESULTS The overall response rate was superior in the radiotherapy arms (radiotherapy alone, 30%; radiotherapy plus vindesine, 34%; vindesine alone, 10%; P = 0.001). However, with a minimum follow-up of 42 months, no improvement in survival has been seen with radiotherapy. The median survival was 8.6 months for patients receiving radiotherapy alone, 9.4 months for those receiving radiotherapy plus vindesine, and 10.1 months for those receiving vindesine (P = 0.58). Radiotherapy also failed to improve long-term survival. The 5-year survivals were 3%, 3%, and 1%, respectively (P = 0.56). CONCLUSION Patients with non-small cell lung cancer who have inoperable, nonmetastatic disease gain no clinically meaningful survival advantage with immediate thoracic irradiation, even when modern megavoltage radiation therapy techniques and equipment are used.
Free carrier absorption in silicon

Free carrier absorption in heavily doped layers reduces the useful photon flux in the photoconductive region of extrinsic Si infrared detectors. A simple theory is developed which predicts the transmissivity of such layers as a function of their sheet resistance and the wavelength of the radiation. Experimental data over the 2.5-20 µm wavelength and 5-500 Ω/square sheet resistance range are given for both diffused and ion-implanted layers and also for polysilicon gases. The temperature dependence of both transmissivity and sheet resistance is investigated from 20 to 300 K.
The organization and function of chromosomes Workshop on Chromosome Structural Elements : from DNA Sequence to Function

Introduction At the end of the summer of 2005, around 60 scientists came together in Rome to discuss various aspects of eukaryotic chromosome biology, including telomeres, centromeres, origins of replication, genome evolution and nuclear organization. Each of these topics is a well-established field with its own specialist meetings and, for the workshop’s participants, this was an unusual and welcome opportunity to hear talks outside their own speciality: the centromere and telomere fields rarely meet! In this report, we consider just a few of the broad range of topics discussed. The telomere In its opening session, the meeting focused on the telomere. In most eukaryotes studied (the notable exception being Drosophila and other dipterans), telomeres are composed of tandem, simple, G-rich repeats. Telomeres have two key functions. First, the complex of proteins that nucleates on the telomeric DNA maintains its structural stability and ensures that the natural end is distinguished from a double-strand break. Second, they provide a mechanism, which operates in immortal cells, to compensate for the progressive loss of DNA from the chromosome end that occurs as a result of ‘conventional’ DNA replication processes. The most common ‘top-up’ mechanism involves the ribonucleoprotein complex, telomerase, which synthesizes telomere repeats de novo at the terminus. Data were presented on telomeric DNA structure, the regulation of telomerase activity, and on non-telomeric roles for some proteins that were thought, until recently, to be telomere-specific.
Striated muscle activator of Rho signalling (STARS) is a PGC‐1α/oestrogen‐related receptor‐α target gene and is upregulated in human skeletal muscle after endurance exercise

Non‐technical summary Exercise improves the ability of skeletal muscle to metabolise fats and sugars. For these improvements to occur the muscle detects a signal caused by exercise, resulting in changes in genes and proteins that control metabolism. We show that endurance exercise increases the amount of a protein called striated muscle activator of Rho signalling (STARS) as well as several other proteins influenced by STARS. We also show that the amount of STARS can be increased by signals directed from proteins called peroxisome proliferator‐activated receptor gamma co‐activator 1‐α (PGC‐1α) and oestrogen‐related receptor‐α (ERRα). We also observed that when we reduce the amount of STARS in muscle cells, we block the ability of PGC‐1α/ERRα to increase a gene called carnitine palmitoyltransferase‐1β (CPT‐1β), which is important for fat metabolism. Our study has shown that the STARS pathway is regulated by endurance exercise. STARS may also play a role in fat metabolism in muscle.
Germ line transformation of the olive fly Bactrocera oleae using a versatile transgenesis marker

The olive fruit fly (olive fly) Bactrocera oleae (Dacus), recently introduced in North America, is the most destructive pest of olives worldwide. The lack of an efficient gene transfer technology for olive fly has hampered molecular analysis, as well as development of genetic techniques for its control. We have developed a Minos‐based transposon vector carrying a self‐activating cassette which overexpresses the enhanced green fluorescent protein (EGFP). Efficient transposase‐mediated integration of one to multiple copies of this vector was achieved in the germ line of B. oleae by coinjecting the vector along with in vitro synthesized Minos transposase mRNA into preblastoderm embryos. The self‐activating gene construct combined with transposase mRNA present a system with potential for transgenesis of very diverse species.
Use of gastric decompression tubes with small-bowel feeding tubes.

My question is in relation to the clinical practice of having an orogastric or nasogastric tube hooked up to intermittent suction while the patient is being fed with a Keofeed tube (Kendall Medical) that is in the duodenum. Is this a proper practice? Is it not safe or is it incorrect to have an orogastric or nasogastric
Laryngo-tracheo-bronchopathia chondro-osteoplastica

Abstract Two cases of laryngo-tracheo-bronchopathia chondro-osteoplastica (LTBCOP) are discussed regarding the pathogenesis of the disease. Our observations support the belief that chronic irritation of the perichondrium in the region of subglottis, trachea and bronchi plays an important role in the aetiology of this disease.
Non‐covalent molecular imprinting with emphasis on its application in separation and drug development

The molecular imprinting technique can be defined as the formation of specific nano‐sized cavities by means of template‐directed synthesis. The resulting molecularly imprinted polymers (MIPs), which often have an affinity and a selectivity approaching those of antibody‐antigen systems, have thus been coined “artificial antibodies. ” MIPs are characterized by their high specificity, ease of preparation, and their thermal and chemical stability. They have been widely studied in connection with many potential applications, including their use for separation and isolation purposes, as antibody mimics (biomimetic assays and sensors), as enzyme mimics, in organic synthesis, and in drug delivery. The non‐covalent imprinting approach, developed mainly in Lund, has proven to be more versatile than the alternative covalent approach because of its preparation being less complicated and of the broad selection of functional monomers and possible target molecules that are available. The paper presents a review of studies of this versatile technique in the areas of separation and drug development, with emphasis being placed on work carried out in our laboratory. Copyright © 2006 John Wiley & Sons, Ltd.
Pancreatic Hormones Disappearance After Total Pancreatectomy in the Duck: Correlation Between Plasma Glucagon and Glucose

The decline of 3 plasma pancreatic hormones, glucagon (G), insulin (I) and somatostatin (S) was studied in fasting ducks after total pancreatectomy. The results show that the decrease of plasma glucose is highly correlated with the disappearance of G, while no important variation of the G/I ratio occurs during the period of observations (80 minutes) the animal being kept fasted. No participation of pancreatic S in glucose metabolism could be detected, the origin of peripheral S in the fasting state seeming due to the intestine for about 50%.
Intravenous thrombolysis.

IJS readers may be interested to know that intravenous (IV) thrombolysis has been used as a standard therapy in acute ischaemic stroke (IS) (1, 2). In the United States, tissue plasminogen activator (tPA) was approved for the treatment of acute IS in 1996, but its use has only recently been accepted by the Department of Medicine of Ho Chi Minh city (HCMC) in 2005. Since 2006, there are three hospitals in HCMC offering thrombolysis for acute IS. The major obstacles for treatment are the cost of drug and the limited therapeutic window, which requires public awareness and organised emergency management. The cost of thrombolysis in Vietnam is not subsidised by government or private insurance; therefore, it is only available for patients who can afford to pay for the drug. The three major stroke units in HCMC managed a total of 6171 patients with acute IS between May 2006 and May 2009. Of these, 121 patients (2%) received IV-tPA based on the inclusion and exclusion criteria of the NINDS study (1). Our study sample had a mean age of 57-years, and 46% were men. Hypertension was the most common vascular risk factor (61%), followed by atrial fibrillation (21%) and diabetes mellitus (17%). The leading TOAST (3) stroke subtype was cardioembolism (35%). The median admission NIHSS score was 12 (range, 5–23), and the median time from symptom onset to administration of an IV-tPA bolus was 143 min. The usual dosage of rt-PA was 0 9 mg/kg. However, in patients who could not afford complete costs of the drug, the dosage was lowered to 0 6–0 9 mg/kg (maximum 50 mg) based on previous data showing that low-dose IVrt-PA administered to Asian patients resulted in relatively good efficacy and safety compared with regular-dose therapy in Western patients (4, 5). Seventy-three (60 3%) patients received standard dose and 48 (39 7%) patients received lower dose (mean calculated IV-tPA dose for these patients was 0.62 mg/kg, range 0 6–0 86 mg/kg). We found that 52 (43%) of patients receiving rt-PA showed an mRS 0–1 at 3-months after receiving IV alteplase therapy, comparable with figures from NINDS (39%) (1). Symptomatic intracranial haemorrhage within 36 h occurred in only (4 1%) of treated patients and 10 (8%) of treated patients died within 3-months of stroke. The majority of patients with IS presenting to our stroke units were ineligible for treatment as only 8 7% of our patients arrived within 3 h. The principal reasons for this may be a lack of awareness of stroke symptoms and a poorly developed ambulance system. Moreover, 5% of eligible patients did not give consent because of a fear of excessive bleeding risk. Our study provides further confirmatory evidence of the safety and feasibility of IV-tPA for treatment in Asian patients with acute IS. More needs to be done to improve public awareness and organisation of services to enable more people to be eligible for treatment.
The Effects of Intrahippocampal Grafts, Training, and Postoperative Housing on Behavioral Recovery After Septohippocampal Damage in the Rat

This study examined whether the expression of behavioral effects of grafts rich in cholinergic neurons placed into the hippocampus of rats with septohippocampal damage may be modulated by postoperative housing or training conditions. Among 91 Long-Evans female rats, 61 sustained a bilateral aspirative lesion of the fimbria-fornix fibers and all overlying tissue, while 30 were given sham operations. Ten days after surgery, fetal septal suspension grafts were performed in the hippocampus of half the lesioned rats. Two days later, all rats were randomly assigned to one of three housing or training conditions: standard, standard with daily training, and enriched. Two and 5 months later, the rats were tested for learning using a Hebb-Williams maze. At both these delays, performance was clearly impaired in lesioned rats and was found to be ameliorated by grafts only in rats which had received daily training. Cresyl violet staining and acetylcholinesterase histochemistry showed that, irrespective of the housing or training conditions, all grafts had survived and provided the denervated hippocampus with a substantial cholinergic reinnervation. Our results suggest that the beneficial behavioral effects of intrahippocampal suspension grafts of septal cells may depend on the postsurgical training or handling conditions of the graft recipients. This result might be of importance for interpreting some behavioral effects of grafts, since in most studies in which grafts were found to induce beneficial behavioral effects (especially on learning capacity), these effects were generally observed at the end of a rather long testing period. Moreover, the present findings show that this delay, before graft function is expressed, might be linked not only to the time needed by grafts to establish a functional reinnervation in the host brain, but also to the training and/or handling conditions of the graft recipient.
Mucositis: pathobiology and management

Purpose of review Oral mucositis remains a frequent debilitating toxicity associated with drug and radiation regimens used to treat cancer. This review highlights the recent understanding of the biological basis, risk factors for, and management for oral mucositis. Recent findings Prevalence and incidence data for mucositis are inconsistent and often underreported. The pathogenesis of mucositis encompasses a sequence of biological events possibly influenced by the oral microbiome and environment. Despite its frequency and severity, there is currently no effective treatment available for the majority of patients at risk. However, with the better understanding of the pathogenesis of mucositis a number of new drugs and biological agents are under investigation. Genome-wide risk prediction tools will allow the identification of patients at risk of developing mucositis. Summary Oral mucositis is a common complication of cancer treatment that may negatively impact the patient's cancer treatment outcome. Despite its frequency and consequences, the lack of effective interventions has frustrated patients and caregivers. Fortunately, a broad range of mechanistically targeted compounds are being developed.
Cross-reactive antibodies induced by a monovalent influenza B virus vaccine

Influenza viruses related to the markedly antigenically divergent strains B/Yamagata/16/88 and B/Victoria/2/87 are circulating in human populations. Adults develop cross-reacting antibodies against recent and earlier influenza B virus strains after vaccination with B/Yamagata/16/88, probably because of previous influenza B virus infections or immunizations. Vaccines containing B/Yamagata/16/88 should adequately protect adults against B/Victoria/2/87 infections.
Neuronal and extraneuronal release of ATP and NAD+ in smooth muscle

Adenosine 5′‐triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD+) are key intracellular constituents involved in energy transfer and redox homeostasis in the cell. ATP is also released in the extracellular space and in the past half century it has been assumed to be the purinergic neurotransmitter in many systems including smooth muscle. In some smooth muscles (i.e., the human urinary bladder detrusor muscle), ATP does appear to be primarily released from nerves upon action potential firings, but in other smooth muscles (i.e., the human large intestine), ATP does not mimic the endogenous purine neurotransmitter. It was recently found that NAD+, another ubiquitous intracellular adenine nucleotide, also follows a regulated release in neurosecretory cells, vascular and visceral smooth muscles, and the brain. In some cases, NAD+ fulfills presynaptic and postsynaptic criteria for a neurotransmitter better than ATP. Therefore, the purine hypothesis of neural regulation in smooth muscle is in need of reevaluation. This article will briefly review the current understanding of neuronal and extraneuronal release of purines in smooth muscle with emphasis on the roles of extracellular ATP and NAD+ and, further, will discuss more recent information about the likely involvement of multiple purines in smooth muscle neurotransmission. © 2012 IUBMB IUBMB Life, 2012, IUBMB Life, 64(10):817–824, 2012
Analyzing Preauthentication Timestamps To Crack Kerberos V Passwords

Platforms, including Microsoft Windows 2000/2003 Servers, utilize Kerberos V for authentication services. Kerberos V introduced several improvements over its predecessor including a preauthentication scheme that authenticates KDC bound requests prior to issuing tickets. Timestamps are incorporated within the preauthentication scheme causing a weakness. The time needed to obtain a password is decreased by capturing and subsequently utilizing this timestamp. This paper examines the computational efficiency obtained by utilizing the timestamp in attacking Kerberos V preauthentication data. We developed a program that would parse the preauthentication data in an attempt to recover the client’s password. It uses a well-known cryptographic library and one embodiment thereof omits the last HMAC computation used in the verification process. Instead a timestamp is used to determine the success of the decryption process. Our findings indicate that utilizing the timestamp saves considerable processing time.