Miracle-dz/UniFAR-FTUs huggingface dataset:
A Web of Thing Middleware for Enabling Standard Web Access Over BLE based Healthcare Wearable Device

An internet of things (IoT) based smart healthcare system may consists of various wearable devices connected through a wireless body area network (WBAN) communication protocol. In one side, the heterogeneity of those connected devices open up a wide opportunity to develop various applications from personal health assistance to massive national healthcare planning. However, in another side, it poses an interoperability challenge since each publishing device may have different message format and communication mechanism. Considering that challenge, the web platform can be seen as promising candidate for providing an interoperability layer as we can abstract various devices as single representation i.e. web resource. In this paper, we propose the design of middleware for enabling efficient web of things access over healthcare wearable devices. The proposed middleware consists of three components: gateway-to-cloud device, messaging service and data access interface. The gateway device has an important role to collect the sensor data perceived by various wearable sensing device through a bluetooth low energy (BLE) protocol. The collected data are then relayed to the a cloud data center using lightweight MQTT messaging protocol. In order to provide an access to the stored data, the system offers two kind of interfaces: the Restful HTTP for non-real time access and MQTT websocket interface to accommodate access on sensing data in real time manner.
Oxidative stress and biomarker of TNF-α, MDA and FRAP in hypertension

Concurrent with the misbalance of oxidizing agents and antioxidants, high blood pressure is a major physical burden condition in the current scenario. Tumor necrosis factor-α (TNF-α) plays a vital role in the pathogenesis of hypertension. Tumor necrosis factor-α, inhibitor improves clinical symptoms however their outcome on high blood pressure has not been investigated. We investigated the inflammatory marker TNF-α, malondialdehyde (MDA) and ferric reducing antioxidant power (FRAP) in hypertensive patients. We measured randomly blood pressure using an ambulatory observe in hypertensive patients, measured systolic BP X 140 mmHg and/or diastolic BP X 90 mmHg were considered hypertensive. Total 60 cases were considered in the study that involves 30 hypertensive patients and 30 normal control. Measurements of serum concentrations of TNF-α, MDA, FRAP in hypertension patients was done in both the groups. Serum TNF-α was found to be remarkably increased in study subjects as compared to normal group (r=0.32, p<0.0001*). Serum MDA was also raised in hypertensive as compared to control (r=0.99**, p<0.0001*). While Serum FRAP was found to be decreased in hypertensive group in comparison to healthy control (r=0.23, p<0.0001*). It is concluded that high blood pressure leads to generation of oxidative stress with remarkable elevation of TNF-α and malondialdehyde levels. While reduced FRAP indicates its probable role in lipid peroxidation and in the pathogenesis of hypertension.
Simulation and Control of an Electric Vehicle by Using PSO and Specify Driving Route Topology

This paper presents modeling and simulation for a pure electric vehicle with the propulsion chain. The PEV be composed of two electric motors to propulsion the vehicle rear wheels, voltage source inverter, a control system which controls both of motors speed and the electronic differential controller (EDC). Two synchronous reluctance motors represent the propulsion system to the EV. The Particle Swarm Optimization (PSO) is used to specify the optimal parameters of the cascade controllers to control the electric motors. The specify driving route topology has designed and used to test vehicle validity under three different operation conditions. The vehicle system has simulated and tested in the Matlab/Simulink environment.
Comparison of Two Types of Cooling of Axial Flux Permanent Magnet Machines by CFD Simulation

This paper is focused on the comparison of two types of possible cooling of the stator of the axial synchronous machine with permanent magnets. The main contribution is the specification of basic issues of the cooling of axial machines. This comparable study is presented the evaluation of suitability as a comparison of two axial flux machine configurations for specific duty cycle. The CFD analysis of the flowing coolant is used to determine the wall heat transfer coefficient.
Aggressive Lane-change Analysis Closing to Intersection Based on UAV Video and Deep Learning

Lane-change is stressful operation for driver, especially when closing to the complex intersection. Accurate analysis the factor that relate to aggressive lane-change is foundation of any future driving safety research. Tracker was using for analyzing aggressive lane-changing behavior that based on amount of naturalistic on-road experiment using an UAV. Over two thousand lane-change video pieces have been recorded, then the selected features are extracted in to matrix. Also, the anonymous drivers and vehicle information is obtained according to license plates. Based on an advanced DBN deep learning algorithm, a relation model of lane-change behavior is constructed by considering the potential influence factors, including vehicle information, driver information, and the driving behavior. Finally, the accuracy of proposed model is validated by comparing to other common models, which approves our model’s superior accuracy, feasibility and concreteness.
Spatiotemporal Traffic Forecasting as a Video Prediction Problem

In this paper we propose an idea of applying video prediction methodologies for urban traffic forecasting. We state that the spatiotemporal structure of traffic data is similar to the structure of video streams, therefore developed video prediction models could be utilized for urban traffic forecasting after some modifications. Recent advances in video prediction led to development of model architectures that deal with large data in video streams and effectively extract high-level spatiotemporal dependencies. Similar problems were addressed in modern studies of urban traffic forecasting. We discuss analogies between these two application areas and discover key issues that should be solved for successful merging of methodologies. These issues are related to different spatial structures (regular grids in video streams and graph-based data in traffic flows) and different extends of spatial non-stationarity (spatial convolution rules are normally constant over the frame for video processing but have natural spatial peculiarities for traffic flows). The proposed idea is illustrated by a developed model that is based on the video prediction methodology and applied for a real-world urban traffic data. The developed model architecture includes custom graph-based rules for spatiotemporal feature learning and the support vector machine as a predictor. Obtained empirical results demonstrate that the proposed model outperforms other state-of-the-art spatiotemporal models (regularized vector autoregressive models, autoregressive integrated moving average model with exogenous spatial predictors). We consider these results as a successful proof of concept and conclude that application of complex video prediction architectures will be beneficial for spatiotemporal urban traffic forecasting.
Design of Rear Wheel Steering System of an Experimental Electric Vehicle

The article deals with a topic of the rear wheel steering of an experimental electric vehicle. Steering of the rear wheel of a vehicle is no new topic, it was being solved ever since the beginning of the vehicle manufacture. The main task of a rear wheel steering is to improve the maneuverability of a vehicle, especially at lower speeds of up to 50 km / h. This solution has recently been seen primarily in vehicles of larger car manufacturers which have higher wheelbase. This solution is also appearing in sports cars, for their better maneuverability in urban environments.
Investigación de excelencia en altura: a cincuenta años de la fundación del Instituto de Investigaciones de la altura de la Universidad Peruana Cayetano Heredia

para el VPH, ya que no protege las partes no cubiertas (5). Por último, aparte del alto costo, debemos tener en consideración algunas cuestiones todavía no resueltas con relación a estas vacunas como el tiempo de duración de la protección; si es necesario o no administrar un refuerzo; sus efectos en la conducta sexual, sobre todo de los jóvenes y sus efectos adversos poscomercialización. Hasta junio del presente año, el Sistema de Reporte de Efectos Adversos de las Vacunas de EE.UU. (VAERS por sus siglas en inglés) había informado 18 727 efectos adversos posteriores a la vacunación con Gardasil, de los cuales 8 % fueron considerados serios. Entre estos se describe al síndrome de Guillain Barre; coágulos en pulmones, corazón y piernas y muerte (68 casos), aunque ninguno de estos eventos serios se ha demostrado que sean atribuibles a la vacuna (6).
Levetiracetam: review clinica ed economica di un nuovo antiepilettico

Uncontrolled epilepsy has a significant negative impact on patient’s quality of life, on his emotional well-being and his social functioning. Seizure places an undue economic burden on the patient and community. The increased costs are direct and indirect (e.g.,inpatient care and loss of earnings associated with time lost from work). Levetiracetam is a new antiepileptic drug used as adjuntive therapy in the treatment of refractory epilepsy. Its nonconventional mechanism of action is not completely understood, but preclinical studies suggest that its antiepileptic action.may depend on a reversible, saturable and stereoselective binding site in CNS membranes. In this paper, we review the main clinical and economic data available in the scientific literature. Levetiracetam has a favourable pharmacokinetic profile characterised by rapid and nearly complete absorption, very low potential for drug interactions and a prolonged pharmacodynamic effect that permits twice-daily dosing. Several placebo-controlled clinical trials have demonstrated that its efficacy has enabled many patients who were refractory to treatment with other antiepileptic drugs to achieve long-term seizure freedom; furthermore in levetiracetam trials the frequency of adverse events is low and withdrawal rates are comparable with those of placebo. A cost/effectiveness analysis compared direct medical costs of levetiracetam add-on therapy with maintenance of standard therapy alone within the UK National Health Service. A 1-year dose escalation decision model was set up in refractory patients who failed to respond to two or more other currently available therapies, with seizure freedom selected as the measure of effectiveness. Available pharmacoeconomic data show that the incremental cost of treating patients with levetiracetam is low when compared with the benefits of seizure freedom, at least in the UK. Furthermore, current studies suggest that this antiepileptic drug has a potential as first-line treatment for many types of epilepsy and in many different patient populations.
On Polar Polytopes and the Recovery of Sparse Representations

Suppose we have a signal y which we wish to represent using a linear combination of a number of basis atoms ai,y=Sigmaixiai=Ax. The problem of finding the minimum l0 norm representation for y is a hard problem. The basis pursuit (BP) approach proposes to find the minimum l1 norm representation instead, which corresponds to a linear program (LP) that can be solved using modern LP techniques, and several recent authors have given conditions for the BP (minimum l1 norm) and sparse (minimum l0 norm) representations to be identical. In this paper, we explore this sparse representation problem using the geometry of convex polytopes, as recently introduced into the field by Donoho. By considering the dual LP we find that the so-called polar polytope P* of the centrally symmetric polytope P whose vertices are the atom pairs plusmnai is particularly helpful in providing us with geometrical insight into optimality conditions given by Fuchs and Tropp for non-unit-norm atom sets. In exploring this geometry, we are able to tighten some of these earlier results, showing for example that a condition due to Fuchs is both necessary and sufficient for l1-unique-optimality, and there are cases where orthogonal matching pursuit (OMP) can eventually find all l1-unique-optimal solutions with m nonzeros even if the exact recover condition (ERC) fails for m.
Lavado peritoneal laparoscópico como tratamiento de diverticulitis aguda perforada

Laparoscopic peritoneal lavage as treatment for acute perforated diverticulitis Introduction: Sigmoid diverticular disease is common in the occidental world and it is responsible for a great number of hospitalizations. The prevalence of diverticular disease increases with age and only in few cases it is manifest as diverticulitis. Diverticulitis produces variable clinical manifestations, ranging from simple inflammation that only requires medical management, to a life threatening condition, due to a free perforation that requires urgent surgery. Clinical case: In this article we present a clinical case of complicated diverticulitis with free perforation treated with laparoscopic peritoneal lavage.
Predictors of adverse maternal and perinatal outcomes in a refugee population from an active conflict country, Syria

Objective: To elucidate predictors of adverse maternal and perinatal outcomes in refugees emigrating from an active conflict region (Syria). Materials and Methods: This study included Syrian pregnant women who gave birth in Etlik Zübeyde Hanım Training and Research Hospital between 2013 and 2016. Adverse perinatal outcomes were defined as preterm labor, premature rupture of membranes, early membrane rupture, intrauterine growth retardation, hypertension, perinatal excites, and erythrocyte-transfused cases. Factors associated with those adverse outcomes were assessed using multiple logistic regression analysis. Results: Having an active smoking habit [odds ratio (OR): 2.647, 95% confidence interval (CI): 1.767-3.965; p<0.001], obesity (OR: 2.272, 95% CI: 1.396-3.699; p=0.001), and adolescent age (OR: 1.732, 95% CI: 1.204-2.491; p=0.003) were found to be the most important predictors of adverse maternal and perinatal outcomes. Eighty of 129 (62%) smokers, 45 of 81 (55.65%) obese individuals, and 91 of 169 adolescents (53.8%) had adverse maternal and perinatal outcomes. Conclusion: Prevention strategies for obesity, smoking, and adolescent pregnancies should be implemented primarily to reduce maternal and antenatal adverse outcomes. Pregnant women with these risk factors in a refugee community emigrating from a conflict-zone nation should be followed up closely.
Supportive supervision to improve service delivery in low-income countries: is there a conceptual problem or a strategy problem?

Supportive supervision is perceived as an intervention that strengthens the health system, enables health workers to offer quality services and improve performance. Unfortunately, numerous studies show that supervisory mechanisms in many low-income countries (LICs) are suboptimal. Further, the understanding of the concept and its implementation is still shrouded in misinterpretations and inconsistencies. This analysis contributes to a deeper understanding of the concept of supportive supervision and how reorganisation of the approach can contribute to improved performance. The effectiveness of supportive supervision is mixed, with some studies noting that evidence on its role, especially in LICs is inconclusive. Quality of care is a core component of universal health coverage which, accentuates the need for supportive supervision. In the context of LICs, it is imperative for supportive supervision to be implemented as an on-going approach. Factors that affect supportive supervision encompass cultural, social, organizational and context dimensions but the capacity of majority of LIC to address these is limited. To this end, we underscore the need to review the supportive supervision approach to improve its effectiveness, and ensure that facility-based supervision embodies as many of the envisioned qualities as possible. We thus make a case for a stronger focus on internal supportive supervision where internal refers to health facility/unit/ward level. Inherent in the approach is what we refer to as ‘supervisee initiated supportive supervision’. The success of this approach must be anchored on a strong system for monitoring, data and information management at the health facility level.
Challenges in Clinical Development of Mesenchymal Stromal/Stem Cells: Concise Review

Identified 50 years ago, mesenchymal stromal/stem cells (MSCs) immediately generated a substantial interest among the scientific community because of their differentiation plasticity and hematopoietic supportive function. Early investigations provided evidence of a relatively low engraftment rate and a transient benefit for challenging congenital and acquired diseases. The reasons for these poor therapeutic benefits forced the entire field to reconsider MSC mechanisms of action together with their ex vivo manipulation procedures. This phase resulted in advances in MSCs processing and the hypothesis that MSC‐tissue supportive functions may be prevailing their differentiation plasticity, broadening the spectrum of MSCs therapeutic potential far beyond their lineage‐restricted commitments. Consequently, an increasing number of studies have been conducted for a variety of clinical indications, revealing additional challenges and suggesting that MSCs are still lagging behind for a solid clinical translation. For this reason, our aim was to dissect the current challenges in the development of still promising cell types that, after more than half a century, still need to reach their maturity. Stem Cells Translational Medicine 2019;8:1135–1148
The predictive value of weight gain and waist circumference for gestational diabetes mellitus

Objective: The first objective of this study was to investigate the relationship between gestational diabetes mellitus (GDM) and gestational weight gain (WG), waist circumference (WC), prepregnancy, and gestational body mass index (BMI). The second aim of our study was to assess the ability of WG, WC, prepregnancy, and gestational BMI with special reference to their cut-off points on predicting the risk of GDM in pregnant women in Turkey. Materials and Methods: A total of 261 women who underwent screening for GDM with the 75-g glucose tolerance test (GTT) between 24th and 28th gestational weeks were included. According to the 75-g oral GTT results, women were classified into two groups: the GDM group and non-GDM group. The data collected included age, parity, plasma glucose level for fasting, 1- and 2-h tests, WC, prepregnancy and gestational BMI, prepregnancy weight, WG during pregnancy, gestational age at birth, and birth weight. Results: WC at 20-24 weeks of gestation, prepregnancy BMI, and gestational BMI had a predictive capacity for GDM. According to our results, optimal cut-off points for the best predictive value of GDM were WC of 100 cm with a sensitivity of 84% and specificity of 70%, prepregnancy BMI of 25 kg/m2 with a sensitivity of 81.8% and specificity of 76%, and gestational BMI of 28.3 kg/m2 with a sensitivity of 75% and specificity of 77.4%. Conclusion: The measurement of prepregnancy BMI, gestational BMI, and WC may be useful in predicting the risk of GDM. Pregnant women with increased prepregnancy BMI, gestational BMI, and WC measurements may be susceptible to the development of GDM.
Modulation of Platelet Functions Assessment during Menstruation and Ovulatory Phases

During menstruation, endometrial hemostasis is achieved by platelet aggregation, fibrin deposition, and thrombus formation that interact with local endocrine and immunological factors which cause termination of menstrual bleeding. Interactions between steroidal sex hormones and platelet functions are not well understood. The aim of this study was to evaluate the effect of platelet function during the menstrual cycle and luteal phase in women of reproductive age. The cross-sectional study on women of reproductive age included 44 healthy women. Platelet function was assessed by PFA-100TM analyzer with collagen/epinephrine and collagen/ADP cartridges during the menstrual cycle and luteal phase. There were no significant differences in platelet function between menstruation and ovulatory phase. Platelet activity in Arab collagen/epinephrine cartridge increased during menstruation compared to non-Arab ethnic subjects and no significant differences in platelet function were found when using collagen/ADP cartridge. This study suggested modulation in platelet functions during menstruation and luteal phase in women of reproductive age. Further studies, including a large number of subjects, platelet genetic and progesterone factors change in platelet clotting associated to menstrual cycle should be conducted.
Combined effect of the entomopathogenic fungus Metarhizium robertsii and avermectins on the survival and immune response of Aedes aegypti larvae

Combination of insect pathogenic fungi and microbial metabolites is a prospective method for mosquito control. The effect of the entomopathogenic fungus Metarhizium robertsii J.F. Bischoff, S.A. Rehner & Humber and avermectins on the survival and physiological parameters of Aedes aegypti (Linnaeus, 1762) larvae (dopamine concentration, glutathione S-transferase (GST), nonspecific esterases (EST), acid proteases, lysozyme-like, phenoloxidase (PO) activities) was studied. It is shown that the combination of these agents leads to a synergistic effect on mosquito mortality. Colonization of Ae. aegypti larvae by hyphal bodies following water inoculation with conidia is shown for the first time. The larvae affected by fungi are characterized by a decrease in PO and dopamine levels. In the initial stages of toxicosis and/or fungal infection (12 h posttreatment), increases in the activity of insect detoxifying enzymes (GST and EST) and acid proteases are observed after monotreatments, and these increases are suppressed after combined treatment with the fungus and avermectins. Lysozyme-like activity is also most strongly suppressed under combined treatment with the fungus and avermectins in the early stages posttreatment (12 h). Forty-eight hours posttreatment, we observe increases in GST, EST, acid proteases, and lysozyme-like activities under the influence of the fungus and/or avermectins. The larvae affected by avermectins accumulate lower levels of conidia than avermectin-free larvae. On the other hand, a burst of bacterial CFUs is observed under treatment with both the fungus and avermectins. We suggest that disturbance of the responses of the immune and detoxifying systems under the combined treatment and the development of opportunistic bacteria may be among the causes of the synergistic effect.
Q A ] 2 2 D ec 2 01 5 Loop Schrödinger-Virasoro Lie conformal algebra

Abstract: In this paper, we introduce two kinds of Lie conformal algebras associated with the loop Schrödinger-Virasoro Lie algebra and the extended loop Schrödinger-Virasoro Lie algebra, respectively. The conformal derivations, the second cohomology groups of these two conformal algebras are completely determined. And nontrivial free conformal modules of rank one and Z-graded free intermediate series modules over these two conformal algebras are also classified in the present paper.