Miracle-dz/UniFAR-FTUs huggingface dataset:
Group model for decentralized federation of Object Creation service

Distributed Object Technology is extending the traditional OO programming model into a distributed environment. It enables remote manipulation of distributed objects in a full lifecycle view. However, current technologies (CORBA or COM) either fail to address the object creation activity of the lifecycle in a balanced way, or are unable to give a proper model for implementing a federated Object Creation service network. In this paper we analyze and clarify some problems associated with object creation activity and service network organization, and propose a group model for implementing decentralized federation of the Object Creation service. After giving a thorough analysis and an implementation design for the model, we conclude that it is a clean-designed, very efficient, and extremely flexible model for our aim. Moreover this model not only ensures the location transparency and efficiency of Object Creation service for programmers, but also gives administrators a flexible, scalable method for managing the service network, which may dynamically restructure itself.
A brief overview on miniature fixed-wing unmanned aerial vehicles

In recent years, research and development of unmanned vehicles have gained much attention in the academic and military communities worldwide. Objects like unmanned aircraft, underwater exploiters, satellites and intelligent robotics are widely investigated as they have potential applications in both military and civilian domains. We present in this paper a brief overview on miniature fixed-wing unmanned aerial vehicles, which includes a review on the historical development of fixed-wing unmanned aircraft, the hardware configuration of the unmanned systems, and some of their representative applications in the military and civilian sectors.
A Reversible Jump Markov Chain Monte Carlo Algorithm for Bacterial Promoter Motifs Discovery

Effective probabilistic modeling approaches have been developed to find motifs of biological function in DNA sequences. However, the problem of automated model choice remains largely open and becomes more essential as the number of sequences to be analyzed is constantly increasing. Here we propose a reversible jump Markov chain Monte Carlo algorithm for estimating both parameters and model dimension of a Bayesian hidden semi-Markov model dedicated to bacterial promoter motif discovery. Bacterial promoters are complex motifs composed of two boxes separated by a spacer of variable but constrained length and occurring close to the protein translation start site. The algorithm allows simultaneous estimations of the width of the boxes, of the support size of the spacer length distribution, and of the order of the Markovian model used for the "background" nucleotide composition. The application of this method on three sequence sets points out the good behavior of the algorithm and the biological relevance of the estimated promoter motifs.
Breakthrough Technologies Synthetic Antisense Oligodeoxynucleotides to Transiently Suppress Different Nucleus-and Chloroplast-Encoded Proteins of Higher Plant Chloroplasts 1 [ OA ]

Selective inhibition of gene expression by antisense oligodeoxynucleotides (ODNs) is widely applied in gene function analyses; however, experiments with ODNs in plants are scarce. In this work, we extend the use of ODNs in different plant species, optimizing the uptake, stability, and efficiency of ODNs with a combination of molecular biological and biophysical techniques to transiently inhibit the gene expression of different chloroplast proteins. We targeted the nucleus-encoded phytoene desaturase (pds) gene, encoding a key enzyme in carotenoid biosynthesis, the chlorophyll a/b-binding (cab) protein genes, and the chloroplast-encoded psbA gene, encoding the D1 protein. For pds and psbA, the in vivo stability of ODNs was increased by phosphorothioate modifications. After infiltration of ODNs into juvenile tobacco (Nicotiana benthamiana) leaves, we detected a 25% to 35% reduction in mRNA level and an approximately 5% decrease in both carotenoid content and the variable fluorescence of photosystem II. In detached etiolated wheat (Triticum aestivum) leaves, after 8 h of greening, the mRNA level, carotenoid content, and variable fluorescence were inhibited up to 75%, 25%, and 20%, respectively. Regarding cab, ODN treatments of etiolated wheat leaves resulted in an up to 59% decrease in the amount of chlorophyll b, a 41% decrease of the maximum chlorophyll fluorescence intensity, the cab mRNA level was reduced to 66%, and the protein level was suppressed up to 85% compared with the control. The psbA mRNA and protein levels in Arabidopsis (Arabidopsis thaliana) leaves were inhibited by up to 85% and 72%, respectively. To exploit the potential of ODNs for photosynthetic genes, we propose molecular design combined with fast, noninvasive techniques to test their functional effects.
Recommendation by Examples

Recommender systems usually rely on user profiles to generate personalized recommendations. We argue here that such profiles are often too coarse to capture the current user’s state of mind/desire. For example, a serious user that usually prefers documentary features may, at the end of a long and tiring conference, be in the mood for a lighter entertaining movie, not captured by her usual profile. As communicating one’s state of mind to a system in (key)words may be difficult, we propose in this work an alternative method which allows users to describe their current desire/mood through examples. Our algorithms utilizes the user’s examples to refine the recommendations generated by a given system, considering several, possibly competing, desired properties of the recommended items set (rating, similarity, diversity, coverage). The algorithms are based on a simple geometric representation of the example items, which allows for efficient processing and the generation of suitable recommendations even in the absence of semantic information.
Biased random sequence generation for making common player believe it unbiased

The players' dissatisfaction in randomness due to their biases is the major problem of game's development. Many games were complained even though the developper selected a good algorithm to generate the randomness. The aim of this study was to reduce negative feedback from player in randomness due to cognitive biases of players. By analyzed the randomness in players' perspective, it was demonstrated that the idealistic randomness is different from the randomness in players perspective. According to the result, the characteristic feature of randomness were defined. Incoperated into pseudorandom algorithm, the natural randomness for players were generated by spacial method. To assure the capability of method and sequences, the evaluation of naturalness were done in the game of "sugoroku". As a result, the natural sequences is natural for player and is able to reduce the dissatisfaction of players in pratical uses.
Electrical properties of PEDOT

This article deals with electric properties of metal-organic semiconductor junction. Different types of substrates were used for measurement of electrical parameters of poly(3,4-ethylenedioxythiophene) (PEDOT). On these substrates, the thick layer of PEDOT was created. Current-voltage characteristics were measured to find-out if Schottky barrier on the metal-emiconductor junction is created. Then frequency characteristics were measured to obtain an equivalent circuit of this system.
An integrative framework for supplier relationship management

Purpose – There have been many studies on topics related to supplier relationship management (SRM), namely purchasing strategy, supplier selection and development, and collaboration with suppliers. However, these studies have not suggested a solution based on an integrative concept, as they focus only on domain‐specific problems. To overcome this limitation, the purpose of this present paper is to suggest a framework for an integrative SRM system by analyzing comprehensive approaches to overall SRM functions. Design/methodology/approach – The paper reviewed and analyzed studies related to SRM from an integrative viewpoint, proposed a framework for an integrative SRM system, and performed a case study based on the analytical hierarchy process with a field survey. Findings – The paper expects that the proposed framework can play a major role in enhancing the efficiency and effectiveness of SRM by adopting an integrative concept because the functions of SRM are highly interrelated. Furthermore, it verifies the applicability of the framework via a case study. Research limitations/implications – Not many approaches are available for organizing evaluators or evaluation sheets, which are used for selecting criteria, providing weight, and evaluating supplier performance, that can secure objectivity of the evaluation; thus, when applying this framework to the industry, special consideration is needed. Practical implications – The proposed framework allows the purchasing members to scrutinize key features of SRM before and during the SRM system operation. Originality/value – The paper provides useful knowledge about the role of SRM systems by holistically approaching SRM‐related processes while suggesting criteria and recommendations to a purchasing manager.
Ethnoecology of Kaleka: Dayak's Agroforestry in Kapuas, Central Kalimantan Indonesia

The aims of the research were to describe the socio-cultural aspect of Kaleka and its floristic diversity. The research was done in two villages in Central Kalimantan, namely, Dahian Tambuk and Tumbang Danau. This study confirms that Kaleka plays an important role in social, cultural and economical aspects of Dayak Kapuas. Plant resources in Kaleka are used and distributed by following two basic principles, namely, equality and sustainability. Local people’s respect to their ancestors is implemented in maintaining and preserving Kaleka in good quality over generations. The philosophical aspect of local people in such villages contributes to Kaleka preservation in the modern era. Kaleka is habitat for many plant species, ranging from understory to upperstory. The species D. Zibethinus, A. heterophyllus, L. domesticum, C. nucifera, C. domestica, N. lappaceum, D. kutejensis, and A. catechu are the most important to local people’s needs. Many species which are found in Kaleka are local and endemic to Kalimantan Island encompassing S. koetjape, M. casturi, D. kutejensis, B. motleyana and P. canescens. These fact shows that Kaleka is potential to be promoted as a key for biodiversity conservation in Central Kalimantan.
A NONLINEAR SPACECRAFT ATTITUDE CONTROLLER AND OBSERVER WITH AN UNKNOWN CONSTANT GYRO BIAS AND GYRO NOISE

A nonlinear control scheme for attitude control of a spacecraft is combined with a nonlinear gyro bias observer for the case of constant gyro bias, in the presence of gyro noise. The observer bias estimates converge exponentially to a mean square bound determined by the standard deviation of the gyro noise. The resulting coupled, closed loop dynamics are proven to be globally stable, with asymptotic tracking which is also mean square bounded. A simulation of the proposed observer-controller design is given for a rigid spacecraft tracking a specified, timevarying attitude sequence to illustrate the theoretical claims.
Regression of pustulosis palmaris et plantaris by periodontal treatment in a subject with severe periodontitis

A 38‐year‐old woman with pustulosis palmaris et plantaris (PPP) was referred to the dentist with a suspicion of metal allergy ( Fig. 1A ). She had noticed the symptoms 3 years previously on her palms and legs. As her symptoms did not improve spontaneously, she visited her dermatologist. There, she was recorded as follows: (1) pustules localized only on the palms and soles; (2) no lesions with eczema or psoriasis on any other parts of the body; and (3) no family history of pustulosis. On the basis of these observations, she was diagnosed with PPP. She was treated with topical application of corticosteroids; however, her symptoms did not improve. Her dermatologist then suspected metal allergy and performed a patch test. Her skin reacted positively with chromium sulfate, zinc chloride, and mercury bichloride. Therefore, she was referred to our dental hospital for the investigation of the possible association of PPP with oral restorative materials.
Ugo1p Links the Fzo1p and Mgm1p GTPases for Mitochondrial Fusion*

In yeast, mitochondrial fusion requires Ugo1p and two GTPases, Fzo1p and Mgm1p. Ugo1p is anchored in the mitochondrial outer membrane with its N terminus facing the cytosol and C terminus in the intermembrane space. Fzo1p is also an outer membrane protein, whereas Mgm1p is located in the intermembrane space. Recent studies suggest that these three proteins form protein complexes that mediate mitochondrial fusion. Here, we show that the cytoplasmic domain of Ugo1p directly interacts with Fzo1p, whereas its intermembrane space domain binds to Mgm1p. We identified the Ugo1p-binding site in Fzo1p and demonstrated that Ugo1p-Fzo1p interaction is essential for the formation of mitochondrial shape, maintenance of mitochondrial DNA, and fusion of mitochondria. Although the GTPase domains of Fzo1p and Mgm1p regulate mitochondrial fusion, they were not required for association with Ugo1p. Furthermore, we found that Ugo1p bridges the interaction between Fzo1p and Mgm1p in mitochondria. Our data indicate that distinct regions of Ugo1p bind directly to Fzo1p and Mgm1p and thereby link these two GTPases during mitochondrial fusion.
Oxidative DNA damage is important to the evolution of antibiotic resistance: evidence of mutation bias and its medicinal implications

Several 1 studies have revealed that the reactive oxygen species (ROS) induced by antibacterial stimulation accelerates the evolution of antibiotic resistance, which uncovered new links between oxygen rise and evolution and inspired new strategies to prevent antibiotic resistance. Considering many other mechanisms cause DNA mutations aside from ROS damage, evaluating the significance of oxidative DNA damage in the development of antibiotic resistance is of great interest. In this study, we examined the ratio of G:C > T:A transversion to G:C > A:T transition in drug-resistant Escherichia coli and Mycobacterium tuberculosis and found that it is significantly higher than the background values. This finding strongly suggests that ROS damage plays a critical role in the development of antibacterial resistance. Considering the long-term co-evolution between host organisms and pathogenic bacteria, we speculate that the hosts may have evolved strategies for combating antibiotic resistance by controlling DNA damage in bacteria. Analysis of the global transcriptional profiles of Staphylococcus aureus treated with berberine (derived from Berberis, a traditional antibacterial medicine) revealed that the transcription of DNA repair enzymes was markedly upregulated, whereas the antioxidant enzymes were significantly downregulated. Thus, we propose that consolidating the DNA repair systems of bacteria may be a viable strategy for preventing antibiotic resistance. 1These authors contributed equally to this work.
Open process innovation: The impact of personnel resource scarcity on the involvement of customers and consultants in public sector BPM

Purpose – Open process innovation – drawing from the literature on open innovation and business process management (BPM) – promotes the study of how to systematically make use of knowledge that lies outside of an organization's boundaries for process‐innovation initiatives. Open innovation has been heavily studied for product innovation; however, process innovation has not yet been researched from such perspective. This paper aims to address these issues.Design/methodology/approach – Against this background, the paper seeks to investigate into variables that impact on the qualities of open process innovation taking the example of the public sector domain. This paper examines how personnel‐resource scarcity exerts influence on the involvement of: customers (here citizens and local companies); and consultants (here management and software consultants) in public sector BPM. Based on the findings, implications for theory and practice are discussed, including implications for studies on BPM maturity or on busi.
Time Stamp Attack on Wide Area Monitoring System in Smart Grid

Security becomes an extremely important issue in smart grid. To maintain the steady operation for smart power grid, massive measurement devices must be allocated widely among the power grid. Previous studies are focused on false data injection attack to the smart grid system. In practice, false data injection attack is not easy to implement, since it is not easy to hack the power grid data communication system. In this paper, we demonstrate that a novel time stamp attack is a practical and dangerous attack scheme for smart grid. Since most of measurement devices are equipped with global positioning system (GPS) to provide the time information of measurements, it is highly probable to attack the measurement system by spoofing the GPS. By employing the real measurement data in North American Power Grid, simulation results demonstrate the effectiveness of the time stamp attack on smart grid.
An Immunohistochemical Study on the Endocrine Cells in the Alimentary Tract of the Red‐Eared Slider (Trachemys scripta elegans)

The regional distribution and relative frequency of endocrine cells in the alimentary tract of the red‐eared slider, Trachemys scripta elegans, were investigated by immunohistochemical methods using 10 antisera. Most of the immunoreactive cells in the intestine were spherical or spindle‐like in shape (open‐type cells), while round cells (closed‐type cells) were occasionally found in the stomach. These immunoreactive cells were located in the basal portion of the intestine, including the oesophagus, and in the gastric glands of the stomach. Cg A‐immunoreactive cells were restricted to the pylorus and duodenum and were few in number. Serotonin‐immunoreactive cells, which were most commonly found in the pylorus, were found in the epithelia throughout the alimentary tract at various frequencies. Gastrin‐immunoreactive cells were found in the pylorus, duodenum and jejunum at moderate, low and very low frequencies, respectively. Somatostatin‐immunoreactive cells were found throughout the alimentary tract except for the rectum, at various frequencies. Glucagon‐immunoreactive cells were detected in the fundus, pylorus, jejunum and ileum at low or very low frequencies. CCK‐8‐immunoreactive cells were found in the pylorus, fundus and duodenum at very low, low and moderate frequencies, respectively. Bombesin‐immunoreactive cells were restricted to the fundus and pylorus at low frequencies. No secretin‐, BPP‐ or VIP‐immunoreactive cells were found in this study.
A Flexible Software Architecture for Hybrid Tracking

Fusion of vision-based and inertial pose estimation has many high-potential applications in navigation, robotics, and augmented reality. Our research aims at the development of a fully mobile, completely self-contained tracking system, that is able to estimate sensor motion from known 3D scene structure. This requires a highly modular and scalable software architecture for algorithm design and testing. As the main contribution of this paper, we discuss the design of our hybrid tracker and emphasize important features: scalability, code reusability, and testing facilities. In addition, we present a mobile augmented reality application, and several first experiments with a fully mobile vision-inertial sensor head. Our hybrid tracking system is not only capable of real-time performance, but can also be used for offline analysis of tracker performance, comparison with ground truth, and evaluation of several pose estimation and information fusion algorithms. © 2004 Wiley Periodicals, Inc.
Hematopoiesis-related microRNA expression in myelodysplastic syndromes

MicroRNAs (miRNAs) are negative regulators of expression of genes involved in hematopoiesis. The present study sought to link hematopoiesis-relevant miRNAs with myelodysplastic syndromes (MDS) and MDS progression to acute myeloid leukemia (AML). We assessed 25 mature miRNAs in total RNA from bone marrow (BM) and peripheral blood (PB) of 25 newly diagnosed patients with MDS and 12 controls. Twelve miRNAs in BM and six in PB were differentially expressed between patients with MDS and controls. Three of these miRNAs, belonging to the cluster 17–92, were overexpressed in both BM and PB. miR-15a in BM ( p = 0.034) and miR-16 in PB ( p = 0.005) were differentially expressed between low-risk and high-risk groups. miR-222 ( p = 0.0023) and miR-181a ( p = 0.014) expression was higher in AML than in MDS in both BM and PB. This study adds further evidence to the role of miRNAs in the pathogenesis of MDS and their transformation into AML.
Gender differences in the relation between number of teeth and systolic blood pressure

Background Tooth loss predicts total and circulatory mortality. The reasons for the increased mortality in subjects with a low number of teeth may be related to enhanced atherosclerosis, elevated arterial pressure and more frequent hypertension. The present study was designed to investigate whether there is an association between the number of teeth and arterial pressure or hypertension. Methods We used data of 4185 adult subjects (2150 women) collected for the population-based Study of Health in Pomerania. The number of teeth was counted by trained and certified dentists. Hypertension was defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg or use of antihypertensive medication. Multivariable analyses were adjusted for relevant confounders. Results The adjusted mean (standard error) systolic blood pressure in men having 0–6 teeth was 149.6 mmHg (1.3 mmHg) compared to 142.6 mmHg (1.2 mmHg) in men having 27–28 teeth (P < 0.05). The adjusted odds for hypertension in men with 0–6 teeth compared to men with 27–28 teeth were 1.91 (95% confidence interval 1.21; 3.02, P < 0.05). In women no such relations were found. Conclusion There is an inverse association between the number of teeth and systolic blood pressure and hypertension in men but not in women. The present findings partly explain the relation between tooth loss and mortality.
Application of 1-methylcyclopropene reduces wound responses and maintains quality in fresh-cut apple.

The objective of this study was to investigate the effects of 1-methylcyclopropene (1-MCP) treatment before cutting on respiration rate, ethylene production, electrolyte leakage, firmness, and color in fresh-cut apple fruit. Fresh-cut apple without 1-MCP treatment had a shelf life of 10 days at 2 degrees C and became browning and decay after pro-long storage. However, fresh-cut apple remained fresh-looking even after 14 days at 2 degrees C when fruit were exposed to 1-MCP before cutting. 1-MCP treatment significantly reduced wound-activated respiration rate and ethylene production, maintained firmness during storage. Visible changes in apple skin color do not occur, however, . L and whiteness index (WI) of flesh in intact and fresh-cut apple applied with 1-MCP were higher than those without 1-MCP treatment. Fresh-cut and intact fruit had little changes in electrolyte leakage after 2 days of storage when 1-MCP was pre-applied. The present study indicated that treatment with 1 microL/L 1-MCP for 10 h at 20 degrees C prior to cutting can significantly reduce wound-active responses in fresh-cut apple.