Miracle-dz/UniFAR-FTUs huggingface dataset:
Pruning SMAC search space based on key hyperparameters

Machine learning (ML) has been widely applied in many areas in recent decades. However, because of its inherent complexity and characteristics, the efficiency and effectiveness of ML algorithm often to be heavily relies on the technical experts' experience and expertise which play a crucial role to optimize hyperparameters of algorithms. Generally, the procedure tuning the exposed hyperparameters of ML algorithm to achieve better performance is called Hyperparameters Optimization. Traditional hyperparameters optimization methods are manually exhaustive search, which is unavailable for high dimensional search spaces and large datasets. Recent automated sequential model‐based optimization led to substantial improvements for this problem, whose core idea is fitting a regression model to describe the importance and dependence of algorithm's performance on certain given hyperparameter setting. Sequential model‐based algorithm configuration (SMAC) is a the‐state‐of‐art approach, which is specified by four components, Initialize, FitModel, SelectConfigurations, and Intensify. In this article, we propose to add a pruning procedure into SMAC approach, it quantifies the importance of hyperparameters by analyzing the performance of a list of promising configurations and reduces search space by discarding noncritical and bad key hyperparameters. To investigate the impact of pruning for model's performance, we conducted experiments on the configuration space constructed by Auto‐Sklearn and compared the effect of run time and pruning ratio with our algorithm. The experiments results verified that, our method made the configuration selected by SMAC more stable and achieved better performance.
NITROGEN FIXING BACTERIA AZOTOBACTER AS BIOFERTILIZER AND BIOCONTROL IN LONG BEAN

Azotobacter is Plant Growth Promoting Rhizobacteria through the mechanism of nitrogen fixation and phytohormon production but this rhizobacteria has a role to control plant diseases. The objective of experiment was to evaluate the activity of Azotobacter as biofertilizers as well as biocontrol on long bean cultivation in damping off endemic land in Ambon city, Maluku Province. The field experiment was arranged in completely randomized block design. Inoculation of long bean by Azotobacter has been done by seed inoculation, soil inoculation before planting, and plant inoculation. Plants treated with Azotobacter received fertilizer NPK of ¾ or ½ dosage recommendation while control plants were received 100% NPK. Research showed that no differences between yield of long bean inoculated with Azotobacter sp +reduced doses of NPK with that of control plants. Any application method of Azotobacter inoculation lowered damping off diseases incidence significantly until 10 days after planting, but no effect of inoculation on late blight at 21 days after planting. This study confirmed that Azotobacter has dual activity to reduce the dose of NPK fertilizer and control damping off.
Convolutional and Recurrent Neural Network for Human Action Recognition: application on American Sign Language

Human Action Recognition (HAR) is an important and difficult topic because of the important variability between tasks repeated several times by a subject and between subjects. This work is motivated by providing time-series signal classification and a robust validation and test approaches. This study proposes to classify 60 American Sign Language signs from data provided by the LeapMotion sensor by using a combined approach with Convolutional Neural Network (ConvNet) and Recurrent Neural Network with Long-Short Term Memory cells (LSTM) called ConvNet-LSTM. Moreover, a complete kinematic model of the right and left forearm/hand/fingers/thumb is proposed as well as the use of a simple data augmentation technique to improve the generalization of neural networks. Results showed an accuracy of 89.3% on a user-independent test set with data augmentation when using the ConvNet-LSTM, while LSTM alone provided an accuracy of 85.0% on the same test set. The result dropped respectively to 85.9% and 81.4% without data augmentation.
Einfluss des Lipopeptides MALP-2 auf den Verlauf der sekundärenPneumokokkenpneumonie nach Influenzavirusinfektion im murinen Modell

6 1 Einleitung . 8 1.1 Die ambulant erworbene Pneumonie . 8 1.1.1 Streptococcus pneumoniae . 9 1.2 Influenza . 12 1.3 Das angeborene Immunsystem der Lunge . 15 1.3. 1 Zytokine . 17 1.3. 2 Interaktion von Immunsystem, Influenzavirus und Streptococcus pneumoniae . 18 1.4 Die lokale TLR-vermittelte Immunstimulation als Therapie der experimentellen bakteriellen Pneumonie . 20 1.5 MALP-2 . 21 1.6 Ziel der Arbeit . 25 2 Material und Methoden . 27 2.1 Studiendesign . 27 2.2 Versuchstiere . 28 2.3 Infektion mit Influenzavirus . 28 2.4 Klinische Überwachung . 29 2.5 MALP-2-Applikation . 31 2.5. 1 Vorbereitung . 31 2.5. 2 Applikation des MALP-2 . 31 2.6 Infektion mit Streptococcus pneumoniae . 32 2.6. 1 Bakterienanzucht . 32 2.6. 2 Infektion . 33 2.7 Präparation der Tiere und Probenentnahme . 33
Asymmetric secretion in budding yeast reinforces daughter cell identity

Asymmetric segregation of cellular factors during cell division produces two cells with different identities. This asymmetry underlies cell fate decisions as well as the ability to self-renew. Asymmetric segregation of protein and RNA to the growing bud of Saccharomyces cerevisiae generates a daughter cell with features distinct from its mother. For example, asymmetric segregation of the transcription factor Ace2 to the newly formed daughter cell activates a gene expression program unique to daughters. Ace2 activates a cohort of genes, including degradative enzymes, which facilitate cell separation exclusively from the daughter. This asymmetric secretion leaves a characteristic ‘bud scar’ chitin ring on the mother. We sought to determine the sufficiency of Ace2 to define a daughter cell state by generating an ACE2 allele which localizes to both mother and daughter nuclei. When Ace2 asymmetry is lost, Ace2 target gene transcription and translation occur in both mother and daughter cells. However, we find that mother cells retain bud scars and maintain asymmetric daughter-specific secretion of the wall degrading enzyme Cts1. These findings demonstrate that while mothers are competent to transcribe and translate Ace2 targets, additional intrinsic factors reinforce the daughter cell state. TOC Summary Asymmetric segregation of the transcription factor Ace2 drives daughter-specific cell separation after cytokinesis. Cells engineered to express Ace2 targets symmetrically produce the cell separation enzyme Cts1. However, secretion remains asymmetric suggesting other daughter-specific factors are required to reinforce the daughter cell identity.
Vibration of a composite elastic beam on an inhomogeneous elastic foundation

The lowest vibration modes of a composite beam resting on an inhomogeneous elastic foundation in the case of a clamped-free boundary condition are investigated. It is observed that the relation between the frequency and foundation constant has an effect on the valid solution of the problem. An asymptotic procedure is employed to derive the eigenfrequencies as well as the eigenforms revealing that only under certain conditions on the ratios of material parameters. Numerical illustrations are presented to confirm that the obtained asymptotic frequencies agree well with the exact frequencies in the lowest frequency range. Comparisons of asymptotic and exact displacements are also presented and a remarkable agreement is observed for high-contrast beam components. MSC 2010: 74A40, 74H45, 74G10
Unravelling evolutionary relationships between epifoliar Meliolaceae and angiosperms

Epifoliar fungi are a group of poorly studied fungal symbionts that coinhabit the surface of living plants. Meliolaceae is the largest group of epifoliar fungi and has been considered as obligate parasites. We investigated the taxonomy of Meliolaceae and the coevolutionary events with their host plants using time‐ calibrated cophylogeny based on large subunit, small subunit, and internal transcribed spacer (ITS) sequence data obtained from 17 different fungal taxa and rbcL, ITS, and trnH‐psbA sequence data from their corresponding hosts. Nine new fungal species are introduced in this paper and Appendiculella is synonymized under Asteridiella. The dominant coevolutionary events during the Cretaceous and Cenozoic are cospeciation and host shift, respectively. We hypothesize that the evolutionary history of epifoliar fungi can be divided into three major periods: origins of families, formations of genera, and diversification of species. The rise of angiosperms prompted the evolution of modern epifoliar fungi and the diversification of orders of Angiospermae fostered the formation of epifoliar fungal genera. Phylogenetically, epifoliar fungal genera can be delimited according to their coevolutionary patterns and divergent periods.
The development of student worksheet based on islamic values in the basic laws of chemical calculations

The relationship between the basic values of the Quran in students life will be a reference to how students learn deeply and develop the knowledge gained. This was related to the core spiritual competencies that are expected to be possessed by students after completing one level of education in Aceh. The aim of this study was to produce student worksheets based on Islamic values in the Basic Laws of Chemical Calculation. Method of this research was R&D with the development model of ADDIE. The subjects of this study were students of class X IPA 3 of Inshafuddin Senior High School in Banda Aceh. Based on the results of the needs analysis, the students' worksheets based on Islamic values in the basic law of chemical calculations were needed. The results of the validation with an expert team that was equal to 89.4%, indicating that the student worksheets are possible to be tested. The positive responses of the questionnaire of students were obtained by 80.90%. Based on these results, it can be concluded that the development of students' worksheets was feasible.
Identification of Giardia duodenalis in environmental and animal samples in Scotland with development of novel approaches of filtration elution

Continuous and reliable monitoring of water sources for human consumption is imperative for public health. For protozoa, which cannot be multiplied efficiently in the lab, concentration and recovery steps are key to a successful detection procedure. Recently, megasonic waves have been employed to efficiently recover Cryptosporidium from commonly used water industry filtration procedures, forming a basis for a simplified and more effective method of elution of pathogens. Sonication methods are already employed in many scientific fields of science as a method of cleaning equipment, disrupting cells or killing pathogens, to name only a few uses. In this paper, we report the benefits of incorporating megasonic sonication into the current methodologies of Giardia duodenalis elution from an internationally approved protocol used within the water industry, the FiltaMax system. The megasonic protocol has many benefits over the current method, including but not limited to; a reduced final volume of eluent allows removal of time-consuming centrifugation steps and a reduction in manual involvement resulting in a more consistent and potentially cheaper method. We also show that megasonic sonication of G. duodenalis cysts provides the option of a less damaging elution method compared to the standard FiltaMax system, although currently the elution from filter matrices is not fully optimised. A notable decrease in recovery of damaged cysts was observed in megasonic processed samples, potentially increasing the abilities of further genetic identification options upon isolation of the parasite from a filter sample. Additionally, we explore the potential of megasonic elution with other filter types with Cryptosporidium demonstrating increases in recovery rate for easily automatable setups. This work paves the way for development of a fully automated method for protozoa elution from water samples.
Hydnora
 : The strangest plant in the world?

Hydnora is a remarkable, yet poorly known genus of parasitic plants which occur in the semi‐arid regions of Africa, Madagascar and southern Arabia. An extreme reduction in morphological features, including the complete lack of leaves, has led to Hydnora’s reputa‐ tion as “the strangest plant in the world. ” Although it is one of the earliest branching parasitic plants in the flowering plant phylog‐ eny, little work has been carried out on the genus and it remains virtually unknown in cultivation (see Movie S1 and Infographic S1). This holoparasitic (non‐photosynthetic) plant, only emerges above ground to flower, can damage infrastructure by bursting through pavements (Maass & Musselman, 2001), and scarcely resembles any other flowering plant. Eight species of Hydnora are now rec‐ ognized (Figure 1), of which one (H. visseri) was identified in 2011 in a market, advertised as a traditional medicine, in Johannesburg (Bolin, Maass, & Musselman, 2011; Williams, Falcão, & Wojtasik, 2011), and another (H. arabica) was only described in 2018 (Bolin, Lupton, & Musselman, 2018). Their unpredictable and elusive flowering, together with their remote distributions, suggest more species await discovery. Local communities may be instrumental in identifying new Hydnora species, making it a good “target” spe‐ cies for ethnobotanical research. Indeed, Hydnora abyssinica was discovered recently in Mozambique, following an ethnobotanical study conducted after rhizomes of Hydnora were found at the stalls of traditional medicine sellers (Williams et al., 2011).
Antivirale Therapie – Mechanismen, Substanzen, Anwendung

Bakterien ließen sich rasch kultivieren und quantifizieren und so konnten Substanzen auf ihre antibakterielle Wirkung getestet werden. Die ersten Antibiotika wurden noch fast zufällig aus Stoffwechselprodukten von Mikroorganismen in der 1. Hälfte des 20. Jahrhunderts entwickelt (so Penizillin und Streptomycin). Der Erfolg der Therapie ließ sich klinisch bei vielen akuten Infektionen in Tiermodellen und im Menschen gut beurteilen, was die erfolgreiche Testung neuer Substanzen erleichterte. Der bakterielle Stoffwechsel und dessen essenzielle Unterschiede zu dem eukaryoter Zellen (v. a. der Proteinbiosynthese) wurden parallel zur Entwicklung weiterer Antibiotikaklassen entschlüsselt.
Quantifying the GHG Reduction versus Battery Size in Diesel Buses with Electrified HVAC

Major North American transit operators are targeting zero-emission bus fleets over the next 10-20 years, but a short-term emissions-reduction solution is required for existing operational fleets. In this work, a detailed system simulation is used to determine the emissions-reduction potential of electrifying only the heating, ventilation, and air-conditioning loads in diesel-based transit buses. The electrical power is provided by a rechargeable Lithium-ion battery. The annual average emissions reduction potential of electrified HVAC in transit buses is quantified versus the battery size and varying environmental conditions. Candidate deployment scenarios are explored for three different cities in North America, and it is found that the emissions reduction per bus is between 7.8-17.1t/year for battery packs between 50-100 kWh.
Formação e impacto das linhas de crédito em tempo de pandemia: práticas e reflexões para os pequenos negócios

This paper aims, through the presentation of specific lines of credit, to bring reflections on possible financial practices for financing small businesses in view of the panorama of uncertainty regarding the duration and impact of the crisis generated by covid-19. The particularities of the current crisis are revealed in a comparative way to the previous crises, highlighting the difficulty in forecasting the need for credit and the low adherence of the lines offered to an emergency situation. To this end, it is proposed to diversify the aid tools with the expansion of credit subsidies, amnesties and extinction of interest, and the necessity of caution in hire credit by small businesses, it is reinforced with careful evaluation and dimensioning of real need for capital in view of business continuity.
Terapia ocupacional y sexo: ¿contradicción o contraindicación?

La sexualidad puede ser considerada como actividad u ocupacion significativa para el ser humano? Es, por tanto, competencia de la terapia ocupacional el abordaje de las alteraciones en el desempeno que surgen en las actividades y ocupaciones relacionadas con la expresion de la sexualidad de las personas? El articulo analiza la implicacion de la Terapia Ocupacional en la intervencion de alteraciones del desempeno en el area de las ABVD, en concreto, en la actividad sexual. Critica la posicion de la terapia ocupacional en la practica al ejercer una actitud contraria a la vision holistica del ser humano que esta postula; ya que, sin duda, la sexualidad forma parte de su realidad cotidiana y para algunas personas es una actividad de gran significacion. La mirada que se proyecta sobre la sexualidad y la discapacidad: tabus, prejuicios, miedos; el analisis de conceptos como actividad u ocupacion; el paradigma de la Terapia Ocupacional y el compromiso de los profesionales son puntos sobre los que se reflexionan. Can sexuality be considered as a significant activity or occupation for human beings? Is it therefore the competence of occupational therapy to address performance alterations that arise in activities and occupations related to the expression of people's sexuality? The article analyzes the implication of Occupational Therapy in the intervention of performance alterations in the area of ABVD, specifically in sexual activity. It criticizes the position of occupational therapy in practice by exercising an attitude contrary to the holistic vision of the human being that it postulates, since, without a doubt, sexuality is part of their daily reality and for some people it is an activity of great significance. The gaze projected on sexuality and disability: taboos, prejudices, fears; the analysis of concepts such as activity or occupation; the paradigm of Occupational Therapy and the commitment of professionals are points on which they reflect. DeCS Terapia ocupacional; sexualidad MeSH Occupational therapy; sexuality ARTICULO OBJETO DE LA RECENSION Pollard N, Sakellariou D. Sex and occupational therapy: ? Contradictions or contraindications? Br J Occup Ther. 2007;70(8):362-5. DOI: S1885-527X2020000100011
Comparison of Maximum Power Tracking using Artificial Intelligence based optimization controller in Photovoltaic Systems

This paper analyzes performance of Artificial Intelligence based optimization controller for the comparative study of maximum power point tracking (MPPT) in PV Systems. Artificial Neural Network (ANN) and Particle Swarm Optimization (PSO) control methods are the two such techniques used, and are simulated in MATLAB-Simulink using Trina Solar TSM-250PD05.08. The simulation results suitably depict the performance of these methods on the basis of some parameters like their rise time, settling time, time taken to reach maximum power point and their efficiency. It is found that maximum power point is tracked in PV systems with greater efficiency using PSO as compared to ANN.
Making the Most of Tier 2 Intervention: What Decisions Are Made in Successful Studies?

Abstract Implementation of Tier 2 or supplemental reading intervention for students who struggle with reading in elementary schools is a nearly universal practice in the United States. Resources exist for assisting schools with selecting evidence-based interventions. However, there are many more explicit and implicit decisions that schools make when implementing evidence-based intervention that may or may not impact the effectiveness of the intervention. In this literature synthesis, we aggregate the decisions made in effective Tier 2 reading interventions to help students improve their reading skills. These decisions include identifying which students would most benefit from specific interventions, how long to schedule intervention time, how to schedule staffing, the types of professional learning supports needed, and decisions based on progress monitoring.
Adaptive Efficient Coding of Correlated Acoustic Properties

Natural sounds such as vocalizations often have covarying acoustic attributes, resulting in redundancy in neural coding. The efficient coding hypothesis proposes that sensory systems are able to detect such covariation and adapt to reduce redundancy, leading to more efficient neural coding. Recent psychoacoustic studies have shown the auditory system can rapidly adapt to efficiently encode two covarying dimensions as a single dimension, following passive exposure to sounds in which temporal and spectral attributes covaried in a correlated fashion. However, these studies observed a cost to this adaptation, which was a loss of sensitivity to the orthogonal dimension. Here we explore the neural basis of this psychophysical phenomenon by recording single-unit responses from the primary auditory cortex in awake ferrets exposed passively to stimuli with two correlated attributes, similar in stimulus design to the psychoacoustic experiments in humans. We found: (1) the signal-to-noise ratio of spike-rate coding of cortical responses driven by sounds with correlated attributes remained unchanged along the exposure dimension, but was reduced along the orthogonal dimension; (2) performance of a decoder trained with spike data to discriminate stimuli along the orthogonal dimension was equally reduced; (3) correlations between neurons tuned to the two covarying attributes decreased after exposure; and (4) these exposure effects still occurred if sounds were correlated along two acoustic dimensions, but varied randomly along a third dimension. These neurophysiological results are consistent with the efficient coding hypothesis and may help deepen our understanding of how the auditory system encodes and represents acoustic regularities and covariance. SIGNIFICANCE STATEMENT The efficient coding (EC) hypothesis (Attneave, 1954; Barlow, 1961) proposes that the neural code in sensory systems efficiently encodes natural stimuli by minimizing the number of spikes to transmit a sensory signal. Results of recent psychoacoustic studies in humans are consistent with the EC hypothesis in that, following passive exposure to stimuli with correlated attributes, the auditory system rapidly adapts so as to more efficiently encode the two covarying dimensions as a single dimension. In the current neurophysiological experiments, using a similar stimulus design and the experimental paradigm to the psychoacoustic studies of Stilp et al. (2010) and Stilp and Kluender (2011, 2012, 2016), we recorded responses from single neurons in the auditory cortex of the awake ferret, showing adaptive efficient neural coding of two correlated acoustic attributes.
Valoración del empleo de Kahoot en la docencia universitaria en base a las consideraciones de los estudiantes

The present study, based on the opinion of the students of the different degrees in the field of Education, evaluates the use of a teaching methodology gamified with Kahoot in higher education, where the smartphone becomes an educational resource. To this end, a non-experimental research of a descriptive nature is carried out, applying an electronic questionnaire to a sample of 241 students in Primary Education degree (69), Pre-school Education degree (78), Pedagogy degree (73) and Social Education degree (29). The results obtained show how the student’s value positively the use of Kahoot, above all as a self-evaluation tool. They also show that they are satisfied with its educational use and that, as future teachers, they would use it. However, although they recognize that the gamma