Miracle-dz/UniFAR-FTUs huggingface dataset:
Minireview Dynamic Reciprocity Between Cells and Their Microenvironment in Reproduction 1

Dynamic reciprocity (DR) refers to the ongoing, bidirectional interaction between cells and their microenvironment, specifically the extracellular matrix (ECM). The continuous remodeling of the ECM exerts mechanical force on cells and modifies biochemical mediators near the cell membrane, thereby initiating cell-signaling cascades that produce changes in gene expression and cell behavior. Cellular changes, in turn, affect the composition and organization of ECM components. These continuous interactions are the fundamental principle behind DR, and its critical role throughout development and adult tissue homeostasis has been extensively investigated. While DR in the mammary gland has been well described, we provide direct evidence that similar dynamic interactions occur in other areas of reproductive biology as well. In order to establish the importance of DR in the adaptive functioning of the female reproductive tract, we present our most current understanding of DR in reproductive tissues, exploring the mammary gland, ovary, and uterus. In addition to explaining normal physiological function, investigating DR may shed new light into pathologic processes that occur in these tissues and provide an exciting opportunity for novel therapeutic intervention. breast, dynamic reciprocity (DR), extracellular matrix (ECM), fibroids, folliculogenesis, mechanotransduction (MT), ovary, ovulation, pathogenesis, uterine leiomyoma
Myotonia Behaviour Scale Validation of question naire for patients with myotonia – Czech version of Myotonia Behaviour Scale

Background: Myotonia is a cardinal symptom of myotonic disorders. The most typical symptom of myotonia is a difficulty in releasing a forceful handgrip. It significantly deteriorates the quality of life to a degree that is disabling. Therefore, many drugs have been tested in myotonia therapy. One of the main issues of clinical trials has been the lack of a conclusive method for the quantification of myotonia. The aim of our study was translation and validation of the Myotonia Behaviour Scale (MBS). This scale was designed for subjective assessment of myotonia severity. Methods: Czech translation was approved by a professional translator and then validated through forwardbackward translation. Repeatability and reproducibility were tested on a sample of 15 patients with myotonic dystrophy type 1 (MD1) and 25 patients with myotonic dystrophy type 2 (MD2). All patients completed one MBS form during a routine visit and a second one two days later. Results: The average MBS score was 2.5 in MD1 group and 1.7 in MD2 group. Correlation coefficients between the first and second completion were 0.965 in MD1 and 0.991 in the MD2 group, respectively. Correlation coefficients between relaxation time of handgrip and MBS score were 0.672 in MD1 and 0.627 in the MD2 group, respectively. Conclusion: MBS is a simple and quick scale suitable for long-term monitoring of patients with myotonia. We reported a significant correlation between MBS score and relaxation time of a forceful handgrip in both groups. Autoři deklarují, že v souvislosti s předmětem studie nemají žádné komerční zájmy. The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study. Redakční rada potvrzuje, že rukopis práce splnil ICMJE kritéria pro publikace zasílané do biomedicínských časopisů. The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers. M. Horáková, T. Horák, O. Parmová, S. Voháňka Neurologická klinika LF MU a FN Brno * MUDr. Magda Horáková Neurologická klinika FN Brno Jihlavská 20 625 00 Brno e-mail: magda.horakova@mail.muni. cz Přijato k recenzi: 18. 5. 2018 Přijato do tisku: 29. 8. 2018
MASTERARBEIT / MASTER’S THESIS

Buddhist meditation techniques are many, whereby mindfulness is by far the most studied, secularized and popular form of meditation in the contemporary West. Interest in mindfulness meditation skyrocketed in the last decade, accompanied by the ever-growing literature in both scientific and public discourses. The primary concern of this thesis, however, is not to engage directly with these scholarly debates, nor to make judgments on whether these Western adaptations of mindfulness meditation practices are right or wrong, good or bad, faithful or unfaithful to the original Buddhist tradition. Instead, this work is composed to unveil “the other side of mindfulness” through the lens of cultural translation, by tracing the historical dynamics of the translation of certain Buddhist meditation techniques into modern clinical settings. Within this thesis, I will offer detailed accounts on how the translated, namely, mindfulness meditation has been selected, simplified, and then codified into a standardized retreat program, which then possesses the potential to move beyond its original social and cultural context. Furthermore, I will show how the translators, Kabat-Zinn and the mindfulness teachers, have translated these Buddhist messages into a modern context, into daily language, into scientific epistemological frameworks, and into new economic relations. In this way, I will argue that Kabat-Zinn, despite some of his ground-breaking work, is not as huge an innovator as is often depicted in the discourse. In fact, many of his ideas that were later popularized by the Mindfulness Movement were already present before mindfulness entered the western discourse.
Networking for Cloud Robotics : a case study based on the Sherpa Project

With the big advances of networking technologies Robots can finally be ”always on”. And, they can now use the almost unlimited computation, memory, and storage resources of large datacenters, overcoming the severe limitations imposed by on-board resources: this is the vision of Cloud Robotics. To make it true, however, network connection should be fast, reliable, and available, with more specific requirements depending on the application scenario. In this paper we investigate how the different network technologies can serve different application scenarios, focusing on a specific one in the framework of an European Project called Sherpa. Sherpa aims at developing a robotic platform to support search and rescue activities in hostile environments like the alpine scenario. We discuss its specific network requisites considering different kinds of data that have to be transported from and to the Cloud and the related requirements in terms of minimum throughput and maximum tolerated delays and losses. We present a possible choice for this specific application scenario and show results of measurements taken from a real network to support our choice.
Clinical significance of plasma level of AT-栿 determination in sepsis patients

Sepsis is the systemic inflammatory response syndrome caused by infection. As studies on its pathogenesis go deeper, it is believed that dysfunction of the coagulation/fibrinolysis system plays an important role in occurrence and development of sepsis. Due to an invasion of microorganisms and their toxins after sepsis occurs, there is imbalance between the coagulation system and the fibrinolytic sytem in the early stage of coagulation[1]. After the coagulation system is activated, a large amount of thrombin and fibrous protein is produced, and the anti-coagulation system is also activated. AT-III, a strong inhibitor of the clotting cascade system, passivates thrombin and inhibits a number of serum protease[2]. After infection and DIC, AT-III is consumed greatly. As a result, the increase of AT-III is regarded as one of the indicators reflecting prognostics of sepsis[3]. The activity of AT-III was determined in the treatment of 76 patients with sepsis hospitalized from January, 2008 to December, 2009, and the clinical significance of AT-III in prognostics of patients with sepsis was touched on. 2. Patient and methods
The impact of military spending on economic growth of Pakistan

A sound national defence is extremely essential for a country’s sovereignty. The geostrategic position of Pakistan and its deterrence policy against neighbouring India have generally been the reasons for stringent military financing. Defence spending affects all sectors of the economy directly or indirectly. This study aims to investigate the influence of government military expenditures on the economic growth of Pakistan over the period 1987-2016. Augmented Dickey-Fuller test has been used for checking the unit root in the data. Autoregressive Distributed Lag (ARDL) bounds testing approach to cointegration has been applied to analyze the relationship between military spending and economic growth. The findings indicate that military expenditure has a positive impact on Pakistan's economic growth in the long-run, however it has negative effect on economic growth in the short-run.
Do temporary contracts cause wage discrimination ?

The purpose of this paper is to asses whether the wide di usion of temporary contracts in several European countries can cause wage penalties. Using the 2007 wave of the European Union Statistics on Income and Living Conditions (EUSILC) cross sectional data referred to six European countries (Austria, Spain, Ireland, Italy, Portugal, United Kingdom), I apply the estimation procedure for the quantile treatment e ect parameters proposed by Firpo (2007) and then compare obtained results with standard quantile regression. Considering the six countries as a whole, there exists a wage discrimination for temporary workers which decreases along the wage distribution ranging from 13,4% at the 10th percentile to 7% at the 90th percentile. I also point out that the price e ect explains the most part of the wage di erential and concerns specially low-earning workers. Further, I note that to evaluate the incidence of the price e ect it is necessary to distinguish between Mediterranean countries, which experienced the largest drop in the Employment Protection Legislation (EPL), and Central and North European countries, where there has been a lower or null trend increase in the incidence of temporary employment. ∗I thank my phd supervisor Paolo Naticchioni for his constructive discussions, suggestions and comments.
Model Comparison with Sharpe Ratios Abstract

We show how to conduct asymptotically valid tests of model comparison when the extent of model mispricing is gauged by the squared Sharpe ratio improvement measure. This is equivalent to ranking models on their squared Sharpe ratios. Mimicking portfolios can be substituted for any nontraded model factors and estimation error in the portfolio weights is taken into account in the statistical inference. A variant of the Fama and French (2018) six-factor model, with a monthly-updated version of the usual value spread, emerges as the dominant model over the period 1972–2015.
The prevalence, distribution and functional importance of lower limb somatosensory impairments in chronic stroke: a cross sectional observational study

Results: Complete somatosensory data was obtained for 163 ambulatory chronic stroke survivors, mean (SD) age 67(12) years, mean (SD) time since stroke 29 (46) months. Overall, 56 % (n=92/163) were impaired in the most affected lower limb in one or more sensory modality; 18% (n=30/163) had impairment of exteroceptive sensation (light touch, pressure, pin-prick), 55% (n=90/163) had impairment of sharp-blunt discrimination, and 19% (n=31/163) proprioceptive impairment. Distal regions of toes and foot were more frequently impaired than proximal regions (shin and thigh). Distal proprioception was significantly correlated with falls incidence (r=0.25; p<0.01), and Centre of Force velocity (r=0.22, p<0.01). The Walking Impact Scale was the only variable that significantly contributed to a predictive model of falls accounting for 15-20% of the variance.
INFLUENCE OF IN OVO INJECTION OF L-ARGININE ON HATCHABILITY AND SOME PHYSIOLOGICAL TRAITS OF INSHAS LOCAL BREED CHICKEN

This study was carried out to evaluate the effect of in ovo injection of different L-arginine (LA) levels (0, 1, 2 and 3%) at day 7 of incubation period on hatchability (%) and some physiological traits of Inshas local breed chickens . Fertile eggs (n=500) from Inshas laying hens were divided into 5 groups (100 eggs in each treatment group) as follow: the first and the second groups were the negative control noninjected group (G1) and the positive control (injected with saline solution) groups (G2); while the 3 , 4 and 5 groups were injected in ovo with different L-arginine (LA) levels (1, 2 and 3%). The criteria of response were on hatchability, blood hematology and biochemical traits, as well as histological changes in duodenum, in terms of villi height, width and surface area. Results revealed a significant (P<0.05) increase of hatchability rate in treated groups (G3, G4 and G5) than the control groups (G1 and G2). However, G3 group has was significantly (P<0.05) the lowest in percentage of hatchability (82.8 %) than in G5 (86.6%), but no significant differences between G4 and G3 and G5 were recorded. The mean values of residual Yolk % and liver (g), were significantly (P<0.05) higher in treated groups G5, G4 and G3 than in control groups. In ovo injection with L-arginine, resulted in a significant (P<0.05) increase in hemoglobin, total white and red blood cells count in treatment groups than control groups. Moreover, PCV (%) and Heterophils (%) were significantly higher in groups G4 and G5 than in groups G1 and G2 but no significant difference among G3 and other groups. On the other hand, lymphocytes % was not significantly affected by in ovo injection with L-arginine among groups. Chicks produced from eggs injected with L-arginine in groups G4 and G5 showed significant increases (P>0.05) in serum glucose and protein concentrations than in other groups and significant decreases (P>0.05) in serum cholesterol, total lipids and triglycerides concentrations compared with G3 and controls. Average of villus length and surface area were significantly higher in groups 5 and 4 than in G3, G2 and G1 groups, respectively. While, duodenum villus width was significantly higher in groups 5, 4 and 3 than in groups 2 and 1. Conclusion: It can be concluded that the in ovo injection of L-arginine the 7 d of incubation would improve hatchability percentage rate, some organ weights, carcass traits and certain blood serum characteristics and hematology, as well as, villus length, width and surface area. Keyword: In ovo injectionhatchability-L-arginine, chicken Abeir, A.M. Eshera et al. 551
EFFECT OF PEG INDUCED WATER DEFICIT STRESS ON PHYSIO-BIOCHEMICAL CHARACTERISTICS OF DIFFERENT PEARL MILLET VARIETIES

The present study aimed to scrutinize six pearl millet varieties, differing in their drought sensitivity to evaluate drought tolerance through physio-biochemical parameters. The main purpose of this work was to screen the highly tolerant and susceptible genotypes under PEG-6000 induced water deficit stress (WDS). WDS was induced in seedling on 10 and 20 day of germination by exposing them to different stress levels i.e. T1 (Control); T2 (5% PEG) and T3 (10% PEG). Significant reductions in parameters viz. shoot length, root length, seedling vigour index I, seedling vigour index II and Membrane stability index was observed. The antioxidant enzyme activity (Catalase and Superoxide Dismutase) was assayed for these varieties under water stress. There was a profound decrease in the Catalase activity whereas the SOD activity was increased in the varieties selected for the study.The water stress induced by supplementing 5% PEG in soil was tolerable by the plants as compared to 10% PEG. The results obtained were useful in screening drought tolerant Pearl Millet genotype.
DELONE MODEL EMPIRICAL TEST SUCCESS AND MCLEAN REGIONAL MANAGEMENT INFORMATION SYSTEM ( SIMDA ) IN THE FRAMEWORK OF REGIONAL FINANCIAL TRANSPARENCY ( STUDY IN PALOPO CITY ) JUNAIDI RAHMAWATI STIE

This study aims to examine the factors that affect the successful implementation of information systems (IS) with indicators of user satisfaction and utilization SIMDA by municipalities Palopo using a combination model of success TAM developed by DeLone and McClean (2003), and Seddon and Kiew (1995). This study was to demonstrate empirically that satisfaction SIMDA application utilization is influenced by the perception of usefulness and perceived ease of which are part of the TAM model and influenced by the quality of service both to the treasurer or external parties related to the utilization of government SIMDA. Applications SIMDA as support to Government Regulation No. 56 of 2005 which requires local governments to hold a regional financial information system to support the management and financial reporting, as the Government Regulation No. 60 of 2008 Article 2 paragraph (1). Kata kunci: Persepsi kegunaan dan kemudahan, keberhasilan penggunaan sistem informasi, SIMDA, Delone dan McLean Model.
Improving state estimation in smart distribution grid using synchrophasor technology : a comparison study

Both the growing number of dispersed generation plants and storage systems and the new roles and functions on the demand side (e.g. demand side management) are making the operation (monitoring and control) of electrical grids more complex, especially in distribution. This paper demonstrates how to integrate phasor measurements so that state estimation in a distribution grid profits optimally from the high accuracy of PMUs. Different measurement configurations consisting of conventional and synchronous measurement units, each with different fault tolerances for the quality of the calculated system state achieved, are analyzed and compared. Weighted least squares (WLS) algorithms for conventional, linear and hybrid state estimation provide the mathematical method used in this paper. A case study of an 18-bus test grid with real measured PMU data from a 110 kV distribution grid demonstrates the improving of the system’s state variable’s quality by using synchrophasors. The increased requirements, which are the prerequisite for the use of PMUs in the distribution grid, are identified by extensively analyzing the inaccuracy of measurement and subsequently employed to weight the measured quantities.
MOTOR SKILL LEARNING WITH FORCE FEEDBACK IN MIXED REALITY

An experimental study of interactions in real and mixed reality learning and control environments will be described. The experiments aim at more insight into the difference between three interaction modes in handling automation systems: interaction with real components, mixed real-virtual handling with visual feedback only and with visual and force feedback. A simple, low cost, and internet based force feedback device will be presented, being a further implementation of the Hyper-Bonds concept, a unified concept to describe complex effort/flow driven automation systems distributed over real and virtual worlds. This work is a step towards a modular mixed reality construction kit allowing design and implementation of automation systems based on an arbitrary distribution of real and virtual components. Copyright © 2004 IFAC
Economic Valuation of the Externalities of Offshore and Onshore Wind farms in Denmark : Results from a Nationwide Choice Experiment Survey

For some years now, the trend in the wind power technology has been towards large offshore wind parks as a promising alternative energy source to solve the challenge of finding on-land sites. Nevertheless, there is a significant economic trade-off between offshore and onshore wind power development. Albeit offshore wind farm might entail lower external costs relative to onshore, it is more costly to produce than onshore. The present study revealed the choice between offshore and onshore wind farms each with location specific settings using an excellent choice experiment design. Everything being equal, the households are willing to pay 540 DKK/year/household to locate the future wind farms offshore as opposed to onshore. When households choose the offshore wind farm, they are willing to pay 173 DKK/year/household to site the future offshore wind farms at 12 Km from the coast as opposed to 8 km. On the other hand, if households choose the onshore wind farm, they are willing to pay 198 and 317 DKK/year/household for having the 2X1.5 MW turbines and 1X3MW turbine, respectively as opposed to 4X750 KW turbines, if all placed at 500 M distance from residential areas. However, given the 1000 M distance, households are willing to pay 196 DKK/household/year for having 4X750 KW turbines in preference to 2X1.5 MW and 1X3 MW turbines. The preference for the onshore distance attribute given the sizes of turbines is mixed. Finally, we found a reasonable degree of preference heterogeneity with regard to socio-demographic and economic characteristics. However, we found limited preference heterogeneity with regard to prior experience to wind farms.
Pendleton, Lavinia (2018)Socioeconomic status and executive functions: parental involvement as a mediating factor during middle-childhood

Previous research has demonstrated the positive link between socioeconomic status (SES) and executive functions (EFs). However, limited studies have investigated the potential mediators which could explain this relationship, specifically during middlechildhood. As this is a period in which important changes in cognitive development take place, it is critical to understand the influencing factors. Since parental involvement has been linked with both SES and EFs, this study explores whether parental involvement mediated this relationship. Parents (N=34) completed SES and parental involvement questionnaires, while their children performed tasks to assess their EFs. This study found a positive relationship between SES and EFs but did not find parental involvement to be a mediator. Potential practical and theoretical implications of the findings are discussed. Socio-economic status Executive Functions Parental Involvement Middle childhood
Gastroprotective activity of hot ethanolic extract oiA ^ ihm ^ attnrMi rhizome in rats

A study to evaluate the gastroprotective activity of hot ethanolic extract (HEE) of Alpinia calcarata Roscoe (Zingiberaceae) rhizomes was carried out in rats. Three doses (500,750,1000 mg/kg) of HEE were evaluated for gastroprotective activity against ethanol induced gastric ulcers. Oral administration of HEE provided dose dependent and significant (P< 0.05) protection against gastric damage caused by ethanol. The gastroprotective effect of HEE was superior than cimetidine, the reference drug. HEE had strong anti­ histamine and antioxidant activities, which could have played an active role in inducing gastroprotection. HEE was devoid of unacceptable side effects: no overt signs of toxicity, hepatotoxicity, renotoxicity or haemotoxicity were observed up to 42 days. However, the weight of the spleen was increased in treated groups possibly indicating lymphoproliferative activity. It is concluded that HEE of A.calcarata rhizome has gastroprotective activity in rats. No immediate dose related serious toxicity was observed.
Effects of nanoparticles titanium dioxide ( TiO 2 ) on biofouling in estuarine environment

A diameter of 12 mm manila rope was cut in1m of length with total of 12 numbers to study the bio-fouling activities. Those samples treated with TiO2 found to be higher resistance to bio-fouling. Bio-fouler such as barnacles, tunicates and bryozoans found to be dominant in untreated samples. Maximum quantities of bio-fouler evaluated in control samples were 215.1 g m, 257.7 g m and 312.8 g m in 10, 20 and 30 days. Minimum biomass recorded was 92.6 g min sample treated with 0.05% TiO2 on 10 days of exposed. After 10, 20 and 30 days of exposed, the higher concentrations of TiO2 showed lower bio-fouling. Aesthetical appearance and compromise physical degradation was observed in both control and treated samples after 20 days.