Miracle-dz/UniFAR-FTUs huggingface dataset:
Conditional Mouse Models of Metastatic Breast Cancer

Breast cancer is the most common malignancy among women worldwide, aff ecting 12% of the Western female population and resulting in ~11.000 new cases and more than 3300 deaths annually in the Netherlands. Th e occurrence of distant metastases accounts for over 90% of breast cancer deaths and is currently the most common cause of death for women aged between 35 and 50 years. Patients with breast cancer are at risk of developing manifest metastases for their entire lifetime. Prevention of metastasis formation entails surgical removal of the primary breast tumor, sometimes combined with local radiotherapy, and systemic (neo)adjuvant hormonal therapy or chemotherapy. Despite these local and systemic therapies, approximately 30% of breast cancer patients will relapse and ultimately die of metastatic breast cancer. Once overt metastatic disease is diagnosed, patients are treated with chemotherapy in a palliative setting. Unresponsiveness of distant metastases to conventional forms of chemotherapy is the central unsolved problem in cancer therapy. Th ere is an urgent need for adjuvant therapies that prevent systemic spread of cancer cells and eradicate disseminated cancer cells and established metastases.
Effects of a National Public Service Information Campaign on Crime Prevention: Perspectives from Social Learning and Social Control Theory.

This study examined the effects of public service advertising from two theoretical backgrounds: social learning theory and social control theory. Traditional social learning theory assumes that learning occurs by subjects performing responses and experiencing their effects, with reinforcement as the main determinant. Social control theory, as defined by Donald Black (1984), emphasizes all practices by which people define and respond to deviant behavior. This study is a secondary analysis of data on the attituCinal and behavioral effects of the crime prevention campaign, "Take a Bite Out of Crime," initiated in 1979 and delivered by television, radio, newspapers, and magazines. Data were collected through 1,454 personal interviews conducted by the Roper Organization. Two-way analysis of variance produced 6 permutations comprised of 54 dependent variables. The study examined variance in: crime prevention behavior, self-estimation of likelihood of future crime prevention behavior, cognitive effects, recall of campaign, social control involving neighborhood integration, and additional social control agents. Results indicated that the effectiveness of public service advertising campaigns is closely tied to interpersonal communication activity within a community and that, on their own, these campaigns rarely, if ever, achieve the intended attitudinal or behavioral results. (Contains 6 tables of data and 31 references.) (CR) Reproductions supplied by EDRS are the best that can be made from the original doLument. EFFECTS OF A NATIONAL PUBLIC SERVICE INFORMATION CAMPAIGN ON CRIME PREVENTION: PERSPECTIVES FROM SOCIAL LEARNING AND SOCIAL CONTROL THEORY by Edward J. Lordan, Ph.D. and Joongrok Kwon, Ph.D. authors can be reached at Villanova University, Department of Communication Arts Villanova, Pennsylvania, 19085
Electronic HRM: four decades of research on adoption and consequences

Abstract Despite the existence of a number of recent reviews of e-HRM research, we still lack a comprehensive understanding of the factors affecting the adoption and consequences of e-HRM. This paper therefore provides a review of four decades of research in this area with the aim to provide a summary and integrative framework as a basis for future research. We found that the factors affecting the adoption of e-HRM can be divided into three areas: technology; organization; and people – we refer to this as the ‘TOP’ framework. In line with we divide consequences into those that are operational, relational and transformational. We also found that there has been a shift both in the goals for e-HRM, from efficiency to improved HR service provision and the strategic reorientation of HR departments; but also that the type of consequences that the literature focuses on has also changed from operational effects, to relational and then transformational outcomes. The paper discussed these shifts in some detail, along with the implications for future research and practice.
How good are citizen weather stations? Addressing a biased opinion

The UK is home to a dense network of Citizen Weather Stations (CWS) primarily set up by members of the public. The majority of these stations record air temperature, relative humidity and precipitation, amongst other variables, at sub-hourly intervals. This high resolution network could have benefits in many applications, but only if the data quality is well characterised. Here we present results from an intercomparison field study, in which popular CWS models were tested against Met Office standard equipment. The study identifies some common instrumental biases and their dependencies, which will help us to quantify and correct such biases from the CWS network.
Study and Analysis of Flyback with Adding RC and CatchWinding Forward DC-DC Power Converter in CCM and DCM

The isolated DC-DC converters are completely separated between the input and the output terminals. However, the non-isolated DC-DC converters would share a common ground between the input and the output terminals. The isolated DC-DC converters can be used as a positive grounding or negative grounding. Furthermore, isolated converters have found wide application recently due to their advantage over non-isolated converters. In addition, electrical isolation of input and output ground connections is for safety. The voltage and current stress on switches can be minimized using transformers. Moreover, the first winding can be used to put in energy into the inductor; as a result, the inductor that could gradually increase the energy from the inductor to the load cannot be available for the other coil. The two significant topologies of the isolated DC-DC converters are flyback converter and catch-winding forward converter. Therefore, the main goal is to analyze and investigate the impact of change in switching frequency, duty ratio, load and the input voltage for every topology and to find the critical points for every topology by comparing the results with every figure done through this work [1].
The effect of extrusion on the degradability parameters of various vegetable protein sources

THE EFFECT OF EXTRUSION ON THE DEGRADABILITY PARAMETERS OF VARIOUS VEGETABLE PROTEIN SOURCES The objective of this study was to determine the effect of extrusion, as a method of heat treatment, on the dry matter (DM) and crude protein (CP) degradability parameters of various vegetable protein sources commonly used in the Western Cape Province, South Africa. The feedstuffs used were lupins (LUP), full fat soybeans (SB), full fat canola seeds (FCS), soybean meal (SBM), canola meal (CM) and sunflower meal (SFM). In the first trial, the degradability parameters were determined according to an in sacco degradability procedure. Four non-lactating Holstein cows, fitted with rumen cannulae, were used in the trial and all cows received the same basal lactation diet. The samples were incubated in dacron bags and bags were removed at intervals of 0, 2, 4, 8, 16, 24 and 48 hours. Dry matter and CP disappearance values were determined and fitted to a onecompartment model by means of an iterative least-square procedure in order to determine the DM and CP degradability parameters. Results indicated that extrusion significantly lowered the effective degradability of the DM-fraction (20.1% on average) of all the feedstuffs, except LUP, and the effective degradability of CP in all the raw materials (27% on average). The second trial was an in vitro degradability trial that ran parallel with the in sacco degradability trial and was done with the aid of a Daisy Incubator (ANKOM Technology Corp., Fairport, NY). The same feedstuffs were tested in both trials. A composited sample of rumen liquor from two of the cows used in the in sacco trial was used for in vitro incubation of the samples. The data obtained in this trial were analyzed in a similar way to that of the in sacco trial. Due to a limited amount of residue left after incubation, CP disappearance could not be calculated at each time interval for SB and SBM in the in vitro trial. In this case, actual disappearance values after 8h were used to compare treatments. Extrusion significantly lowered the effective degradability (as determined in vitro) of DM in all the feedstuffs tested
The effect of dynamic loading on the shear strength of pyroclastic cineritic soils and implications for landslide hazard: The case of Pudahuel Ignimbrite, Chile

The co-seismic and post-seismic behaviour of pyroclastic ash deposits and its influence on slope stability remains as a challenging subject in engineering geology. Case studies in volcanic areas of the world suggest that soil structural changes caused by seismic shaking results in landslide activity. It is critical to constrain how this kind of soils behaves during coseismic ground shaking, as well as the effects of dynamic loading on shear strength parameters after shaking. Direct shear tests carried out on cineritic volcanic materials from the Pudahuel Ignimbrite Formation in central Chile show a direct effect of cyclic loading on the shear strength, and in a minor extent on the rheology. A high apparent cohesion found in monotonic shear tests, likely attributed to suction and cementation, is destroyed by dynamic loading. At the same time, the internal friction angle rises. This defines a differential post-dynamic behaviour depending on normal effective stress conditions, which favour the occurrence of shallow landslides. These results show how the use of shear strength parameters obtained from standard monotonic direct shear tests may produce misleading results when analyzing seismic slope stability in this type of soils.
Review of tools for friction stir welding and processing

Abstract Friction stir welding (FSW) is a novel green manufacturing technique due to its energy efficiency and environmental friendliness. This solid state joining process involves a rotating tool consisting of a shoulder and/or a probe. The shoulder applies a downward pressure to the workpiece surface, constrains the plasticised material around the probe, generates heat through the friction and causes plastic deformation in a relatively thin layer under the bottom surface of the shoulder. The rotating probe mainly drags along, plasticises, and mixes the adjacent material in the stir zone, creating a joint without fusion. Friction stir processing (FSP), a variant of FSW, has been developed to manufacture composites, locally eliminate casting defects, refine microstructure and/or improve the associated mechanical and physical properties including strength, ductility, fatigue, creep, formability and corrosion resistance. However, major challenges such as tool design and wear currently limit the use of FSW/P for manufacturing applications, particularly for high melting temperature or high strength alloys. In this review, the FSW/P tools are briefly summarised in terms of the tool types, shapes, dimensions, materials and wear behaviours. Le soudage par friction-malaxage (SFM) est une technique nouvelle de fabrication verte grâce à son efficacité énergétique et à son amicalité environnementale. Ce procédé d’assemblage à l’état solide implique un outil de rotation constitué d’une épaulement et/ou d'un pion. L’épaulement applique une pression vers le bas sur la surface de la pièce de travail, contraint le matériel plastifié autour du pion, engendre de la chaleur au moyen de la friction, et conduit à la déformation plastique dans une couche relativement mince sous la surface du bas de l’épaulement. Principalement, le pion en rotation entraîne, plastifie et mélange le matériel adjacent dans la zone de mélange, créant une jonction sans fusion. Le traitement par friction-malaxage (TFM), une variante du SFM, a été développé pour fabriquer des composites, pour éliminer localement les défauts de moulage, pour raffiner la microstructure et/ou pour améliorer les propriétés mécaniques et physiques associées, incluant la résistance, la ductilité, la fatigue, le fluage, la formabilité et la résistance à la corrosion. Cependant, des défis majeurs comme le concept de l’outil et l’usure limitent présentement l’utilisation de S/TFM dans les applications de fabrication, particulièrement pour les alliages à haute température de fusion ou à haute résistance mécanique. Dans cet examen, on résume brièvement les outils de S/TFM par rapport aux types d’outils, à leurs formes, à leurs dimensions, aux matériaux et aux comportements d’usure.
Low abundance and skewed population structure of the whelk Stramonita haemastoma along the Israeli Mediterranean coast

Stramonita (=Thais) haemastoma (Kool, 1987), a relatively large predatory snail found in rocky littoral ecosystems, can attain densities of hundreds of individuals per m 2 in warm temperate coasts of the western Atlantic. It has also been reported as common along the Israeli Mediterranean coast; however our preliminary observations there suggested low abundances of this species. We measured densities of the whelk and those of its major potential prey by quadrat and belt transect (plots) methods, supported by underwater photography when applicable. Our study demonstrates that indeed densities of S. haemastoma along the Israeli Mediterranean coast are very low (<0.5 m -2 ) in most habitats and locations, with the exception of some midlittoral habitats (density of ca 7 snails m -2 ) where food and shelter are abundant. Food is probably not a limiting factor in most midlittoral habitats, and the low abundance of S. haemastoma is likely to be associated with scarcity of shelters and high risk of dislodgment or of desiccation. The population structure of the whelks is skewed to large snails. Small individuals were absent throughout the entire 5 yr of the study, while mean whelk size increased during this period. These results suggest impaired recruitment of whelks in recent years. Assuming that S. haemastoma was once abundant along the Israeli coast, it is possible that the following contemporary changes which occurred in the Levant basin may have affected whelk repro- duction and/or juvenile survival rates and therefore may also explain the low recruitment rates: (1) diminished seasonal reduction in salinity due to the damming of the Nile; (2) unregulated use of tributyltin-based antifouling paints in Israel, which may impair reproduction through imposex; and (3) massive periodic appearance of a new plankton feeder along the Israeli coast, the Indo-pacific jel- lyfish Rhopilema nomadica, which may prey on the snail larvae.
The prevalence of typhoid fever in Bingham University

Typhoid fever remains a major cause of enteric disease and a significant public health problem. The disease is said to be very prevalent in the developing countries, of which Nigeria is one. The aim of this study is to determine the prevalence of typhoid fever among Bingham University students. A total of 125 blood and stool samples were collected randomly from both male and female students of Bingham University. The blood samples were tested for salmonella antigen using Widal test while stool samples were cultured on Salmonella/Shigella agar for the isolation of the causative agent. From the Widal test 80 (69.6%) samples were positive for Salmonella typhi infection, while the stool culture yielded 94 (75.2%) samples that showed the presence of Salmonella typhi. The gender distribution showed that the prevalence was higher in female students (87.30%) than the male students (62.90%). The infection was highest in the age group of 21-25 years which had 86.36% prevalence. The lowest prevalence was observed in the age group 26-30 years with 46.15%. The prevalence of typhoid fever is generally high in the University. Therefore, proper sanitary measures should be observed by the students in the university. The results also proved the superiority and reliability of stool culture technique over the Widal test in the diagnosis of Salmonella typhi infection. This study will provide the school administration adequate knowledge on the infection and serve as a guide in proffering solution to halt further spread of the disease in the institution.
Indifference Pricing in a Basis Risk Model with Stochastic Volatility

The aim of this dissertation is to study exponential indifference pricing in a basis risk model of one tradable asset and one correlated non-tradable asset in which a claim on the non-tradable asset is hedged using the tradable asset. We extend this to incorporate stochastic volatilities for both assets, driven by a common stochastic factor, and look for the corresponding indifference price characterisation under such a model. We would also look at the optimal portfolio in hedging the claim on the non-tradable asset, the residual risk process and the payoff decomposition of the claim involving the indifference price process and a local martingale. Towards the end of the discussion, we would outline a procedure which one could use to obtain numerical results for the indifference price under this model.
Prevention of SQL Injection Attack on Web Applications

SQL injection is a technique where the attacker injects an input in the query in order to change the structure of the query intended by the programmer and gaining the access of the database which results modification of the user‘s data. In the SQL injection it exploits a security vulnerability of data occurring in database layer of an application. SQL injection attack is the most common attack in websites in these days. Some malicious codes get injected to the database by unauthorized users and get the access of the database due to lack of input validation. Input validation is the most critical part of software security that is not properly covered in the design phase of software development life-cycle resulting in many security vulnerabilities. This paper presents the techniques for detection and prevention of SQL injection attack. There are no full proof defences available against such type of attacks. In this paper some predefined method of detection and modern techniques are discussed. This paper also describes countermeasures of SQL injection.
An Automatic Procedure for the Estimation of the Tail Index

Extreme Value Theory is increasingly used in the modelling of financial time series. The non-normality of stock returns leads to the search for alternative distributions that allows skewness and leptokurtic behavior. One of the most used distributions is the Pareto Distribution because it allows non-normal behaviour, which requires the estimation of a tail index. This paper provides a new method for estimating the tail index. We propose an automatic procedure based on the computation of successive normality tests over the whole of the distribution in order to estimate a Gaussian Distribution for the central returns and two Pareto distributions for the tails. We find that the method proposed is an automatic procedure that can be computed without need of an external agent to take the decision, so it is clearly objective.
Modelling and Numerical Studies of Discrete Dislocation Dynamics

We investigate a possible inaccuracy in discrete dislocation dynamics (DDD) simulations. As a model problem we consider two distinct dislocations of the opposite signs, gliding and bowing out in parallel slip planes in a channel of persistent slip band (PSB). Dislocations are pushed by the applied stress and when overlap, they either pass or form a dipole. The objective of our study is to determine the lower and upper estimate of the passing stress needed to escape each other. In our simulations, we consider two loading regimes - the stress controlled and the total strain controlled regime. The motion law is described by the mean curvature flow of planar curves and treated by the parametric method. Results of our numerical experiments indicate that the upper and lower estimate of the passing stress differ less than 10%.
Investigation of the deformation of homogeneous poly(ethylene-co-1-octene) by wide- and small-angle X-ray scattering using synchrotron radiation

The deformation behavior of homogeneous ethylene-1-octene copolymers was investigated as a function of the crystallinity and the crystal size and perfection, respectively, by wide- and small-angle X-ray scattering using synchrotron radiation. The crystallinity and the crystal size and perfection, respectively, are controlled by the copolymer composition and the condition of melt crystallization. The deformation includes rotation of crystals, followed by plastic deformation and complete melting of the initial crystal population, and final formation of microfibrils. The process of rotation, plastic deformation, and melting of crystals of the initial structure is completed at lower strain if the size and perfection of the crystals, respectively, decrease, that is, if crystals thermally melt at lower temperature. The kinetics of the fibrillation of the initial structure seems independent of the crystal symmetry, that is, rotation and melting of pseudohexagonal and orthorhombic polyethylene crystals (as evident in low-crystalline specimens) are similar. The structure of the microfibrils, before and after stress release, is almost independent of the condition of prior melt crystallization, which supports the notion of complete melting of the initial crystal population. © 2002 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 40: 1919–1930, 2002
Channel Selection for Wearable Wireless Devices in the THz Range (Bachelorarbeit)

Wearable wireless devices (WWDs) carried on the human body are expected to play an important rule in future body area networks. Recent works have indicated that the THz (Terahertz) band (0.1− 10 THz) possesses attractive properties for the development of such systems, especially for reducing the interference when multiple WWD bearers exist in closed proximity. In this thesis, we consider a system of WWDs where each device selects a channel from a set of K orthogonal channels, with a bandwidth of approximately 2 GHz per channel, located in the THz Band. The goal is to investigate how the frequencies choices of these channels influence the performance of a WWD system for different user densities.To this end, the cumulative distribution function (CDF) of the signal-to-noise-interference-plus-noise ratio (SINR)of the users in such scenarios for different frequency choices will be analyzed. Los dispositivos inalámbricos portátiles (WWDs) que se usan sobre el cuerpo humano jugarán un papel muy importante en las redes de area corporal. Recientes trabajos han indicado que la banda de (0.1−10) THz (Terahercios) posee propiedades muy atractivas para el desarrollo de estos sistemas, especialmente para reducir la interferencia cuando múltiples WWDs están muy próximos. En este trabajo fin de grado, consideramos un sistema de dispositivos inalámbricos portátiles donde cada sistema selecciona un canal de un conjunto de K canales ortogonales, con una banda de 2 GHz por canal, localizados en la banda de THz. El objetivo es investigar cómo la elección de frecuencia de estos canales influye la representación de los sistemas de WWD para diferentes densidades de usuarios. Para finalizar, la función de distribución acumulada (CDF) de la signalto-interference-plus-noise ratio(SINR) de los usuarios cuando estos eligen diferentes frecuencias en escenarios será analizado. Els dispositius sense fils portátils (WWDs) que s’usen en el cos humá jugaran un paper molt important en les xarxes d’area corporal. Recents treballs han indicat que la banda de (0, 1− 10) THz posseeix propietats molt atractives per al desenvolupament d’aquests sistemes, especialment per reduir la interferéncia quan multiples WWD estan molt próximos. En aquest treball fi de grau, considerem un sistema de dispositius sense fil portátils