Miracle-dz/UniFAR-FTUs huggingface dataset:
Early diagnosis of mycosis fungoides and Sézary's syndrome by morphometric analysis of lymphoid cells in the skin

Mycosis fungoides (MF) and Sézary's syndrome (SS) are cutaneous T‐cell lymphomas characterized ultrastructurally by the presence of lymphoid cells with deep and narrow nuclear indentations (cerebri‐form mononuclear cells or CMC). Early diagnosis of MF and SS is difficult because in their early stages they often resemble various forms of chronic, benign skin lesions. By measuring the frequency distribution of a nuclear shape parameter (nuclear contour index or NCI) of lymphoid cells in skin infiltrates using computer assisted planimetry, we tried to classify suspect cases into the malignant and benign groups. From 12 patients with MF or SS (malignant group) and 11 patients with chronic, benign skin lesions (benign group) the frequency distribution of the NCI of the lymphoid cell population was measured. Nonlinear discriminant analysis selected the 70th and 25th percentile of the NCI distribution of the lymphoid cells in the skin infiltrates as parameters by which these patients could be classified correctly into the malignant or benign groups with a probability of over 95%. The predictive value of these parameters was tested on ten patients suspected of having cutaneous T‐cell lymphomas. Three cases were classified as benign and 7 as malignant. In a three‐year follow up cutaneous T‐cell lymphomas did not develop in any of the 3 cases classified as benign, MF developed in 5 of 7 cases classified as malignant, 1 patient has lymphomatoid papulosis and 1 patient is still suspect for MF. These results are compared with those of DNA cytophotometry performed on skin imprint preparations. It is concluded that morphometry of lymphoid cells in skin lesions of patients suspect for MF and SS can make an important contribution to an early diagnosis of MF or SS.
Validated Model of a Pressure Microprobe for Water Relations of Plant Cells

Turgor pressure is a physiologic variable of fundamental importance. It is a component of water potential and a measure of water status in a plant. For a long time direct measurement of turgor pressure was not possible. Three decades ago a pressure probe technique was originally introduced to measure turgor pressure and water relations of higher plant cells. Early experiments were made with a glass capillary linked to a pressure chamber, filled with silicone oil. After the vegetable cell to be punctured with the tip of the capillary, a sensor was used to measure the pressure in the chamber. From then until now the usual procedure has been to detect the meniscus position at the moment that the cell is punctured and manually, or automatically, to return the meniscus to the original position. When this occurs the pressure in the chamber is measured with a sensor. Some attempts were made to get the instrument automated but there is no systematic description about it. Based on this, it is proposed a dynamic model for the hydraulic system that can be helpful to design a closed loop system aiming an automated instrument. It is also shown that the theoretical model reasonably matches the experimental results.
Uterine and umbilical blood flows and net nutrient uptake by fetuses and uteroplacental tissues of cows gravid with either single or twin fetuses.

To evaluate the influence of cow breed and number of fetuses on uterine and umbilical blood flows and nutrient fluxes or uterine tissues from gravid cows, surgery was performed on Charolais or Hereford cows with single or twin fetuses at 177 +/- . 2 d (mean +/- SEM) after mating. Indwelling catheters were placed in a fetal femoral artery and vein, in an umbilical vein of each fetus, and in a uterine artery and vein of each gravid horn. Deuterium oxide (D2O) was infused into a fetal femoral vein at 183 +/- . 3 and 190 +/- . 5 d after mating to estimate uterine and umbilical blood flows (liters/minute). Blood oxygen and plasma glucose and lactate concentrations were determined and uterine arterio-venous (A-V) and umbilical venous-fetal arterial (v-a) differences and net uterine and fetal uptakes were calculated. Net utilization by the uteroplacenta was calculated as the difference between uterine and fetal net uptakes. Uterine blood flows were lower (P less than .01) in Hereford (4.80 +/- .28) than in Charolais (7.07 +/- .33) and lower (P less than .01) per fetus in cows with twin fetuses (5.22 +/- .34) than in cows with a single (6.65 +/- .28) fetus. Umbilical blood flows were greater for single than for twin fetuses. Fetal oxygen and glucose net uptakes averaged 57 and 12%, respectively, of net uteroplacental utilization. Lactate was released from uteroplacental tissues to fetal (42%) and maternal circulations (58%). Fetal oxygen uptakes tended to be less for twin fetuses (P = .08) than for a single fetus. (ABSTRACT TRUNCATED AT 250 WORDS)
A Causal Model of Burnout Among Self-Managed Work Team Members

Abstract The findings on burnout that are almost universally from research in service settings are applied to an industrial setting with self-managed work teams. Researchers formulated several hypotheses on the basis of this literature. These hypotheses were then used to develop a structural (causal) model that was tested and refined using LISREL 8. Data were collected from 320 employees concerning perceptions of several job and organization conditions, as well as the three components of burnout. Results indicated that role conflict contributed to emotional exhaustion, and participation in work teams diminished it. Job ambiguity, low co-worker support, and low job ability contributed to feelings of low personal accomplishment. These results were consistent with previous findings. When insufficient time to complete a job was removed from the workload measures, workload actually diminished burnout, a finding opposite from previous research. Other organization factors had no significant impact on burnout in this setting.
Cardiovascular Complications After Renal Transplantation and Their Prevention

By the time of renal transplantation, end-stage renal disease patients have a huge burden of cardiovascular disease (CVD) and are heavily saturated with atherosclerotic risk factors. Worsening of preexisting risk factors or new CVD risk factors may develop in the posttransplant period consequent in part to the diabetogenic and atherogenic potential of immunosuppressive drugs. The annual risk of a fatal or non-fatal CVD event of 3.5 to 5% in kidney transplant recipients is 50-fold higher than the general population. Renal allograft dysfunction, proteinuria, anemia, moderate hyperhomocysteinemia and elevated serum C-reactive protein concentrations, each dependently confer greater risk of CVD morbidity and mortality in the posttransplant period. Long-term care of renal transplant recipients should programmatically incorporate the recommendations of the National Kidney Foundation Working Groups and European Best Practice Guidelines Expert Group on Renal Transplantations into the management of hypertension, dyslipidemia, smoking, and posttransplant diabetes mellitus. Timely utilization of coronary revascularization procedures should be undertaken as these treatments are equally effective in the kidney transplant population.
Comparison of milk production and milk composition for an exotic and a local synthetic rabbit lines

Aim: Basic objective of this research was to compare two rabbit lines: V-line (exotic line), Alexandria (local synthetic line) for yield and composition of milk product and their effect on productive performance of rabbits. Materials and Methods: The experiment was conducted on 80 does and their kits. Milk yield (MY) of each doe and milk composition (MC) were recorded at 3rd week of lactation. Results: The results of MY showed insignificant difference between V-line and Alexandria line. While the results of MC indicated significant differences in milk protein and fat between the two lines. The protein electrophoresis was used for assaying variation in milk proteins between the two lines. The banding protein patterns showed seven protein bands for Alexandria line and six bands for V line. The results demonstrated one specific protein marker at 48 KDa (κ-casein) in Alexandria doe’s milk. Moreover, the results of individual body weight at weaning age indicated that Alexandria rabbits had significantly higher body weight compared with V-line rabbits (845.33 g, 664.05 g, respectively). Alexandria line had significantly lower mortality rate compared with V-line (1.5%, 2.7%, respectively). Conclusion: The differences which obtained in Alexandria line milk may play an important role in the productive performance of rabbits.
Presence of human papillomavirus type‐16 and type‐18 DNA sequences and their expression in cervical cancers and cell lines from japanese patients

Southern blot analyses of surgical specimens of cervical carcinoma from Japanese patients showed that 3/9 samples contained human papillomavirus (HPV) type‐16 DNA sequences, and 2 contained HPV type‐18 DNA sequences. By Northern blot analyses, RNA transcripts of HPV DNA sequences were demon‐trated in some of the tissues containing HPV type‐16 or HPV type‐18 DNA sequences. Two cell lines established from cervical cancers of Japanese patients also contained HPV type‐18 genomes and these cell lines contained HPV type‐18 transcripts. Two other cervical cancer cell lines from a Japanese patient were found to contain HPV type‐16 DNA sequences and their RNA transcripts.
Strong Stationarity for Optimal Control of the Obstacle Problem with Control Constraints

We consider the distributed optimal control of the obstacle problem with control constraints. Since Mignot proved in 1976 the necessity of a system which is equivalent to strong stationarity, it has been an open problem whether such a system is still necessary in the presence of control constraints. Using moderate regularity of the optimal control and an assumption on the control bounds (which is implied by $u_a < 0 \le u_b$ quasi-everywhere in $\Omega$ in the case of an upper obstacle $y \le \psi$), we can answer this question in the affirmative. We also present counterexamples showing that strong stationarity may not hold if $u_a < 0$ or $0 \le u_b$ are violated. (An erratum is attached.)
Integrating Public Data Sets for Analysis of Maternal Airborne Environmental Exposures and Stillbirth

Efforts to study relationships between maternal airborne pollutant exposures and poor pregnancy outcomes have been frustrated by data limitations. Our objective was to report the proportion of Ohio women in 2006-2010 experiencing stillbirth whose pregnancy exposure to six criteria airborne pollutants could be approximated by applying a geospatial approach to vital records and Environmental Protection Agency air monitoring data. In addition, we characterized clinical and socio-demographic differences among women who lived within 10 km of monitoring stations compared to women who did not live within proximity of monitoring stations. For women who experienced stillbirth, 10.8% listed a residence within 10 km of each type of monitoring station. Maternal race, education, and marital status were significantly different (p<0.0001) comparing those within proximity to monitoring stations to those outside of monitoring range. No significant differences were identified in maternal age, ethnicity, smoking status, hypertension, or diabetes between groups.
Wealth, marriage and prenuptial agreements in France (1855 - 2010)

Cet article A©tudie lâ€™A©volution des contrats de mariage, des rA©gimes matrimoniaux et de la dot en France sur la pA©riode 1855-2010. Ces sA©ries historiques montrent que les aspects A©conomiques du mariage ont sensiblement changA© au cours du temps. PremiA¨rement, le contrat de mariage a A©tA© frA©quemment utilisA© par les couples pour se dA©partir du rA©gime matrimonial par dA©faut, que ce soit pour limiter les pouvoirs A©conomiques du mari ou pour protA©ger le conjoint survivant par exemple. DeuxiA¨mement, cet article met en A©vidence les changements dans la nature du patrimoine causA©s par le dA©clin des rA©gimes de communautA© et lâ€™essor du rA©gime de la sA©paration de biens depuis les annA©es 1960. Cette individualisation du patrimoine sâ€™oppose A la prA©A©minence des rA©gimes de communautA© depuis la crA©ation du Code Civil en 1804. Cette A©volution peut Aatre vue comme une amA©lioration du statut des femmes mariA©es qui se sont progressivement A©mancipA©es de lâ€™autoritA© du pA¨re puis de celle du mari. Dâ€™un point de vue patrimonial, nous montrons que le retour du patrimoine en France sâ€™accompagne dâ€™un changement dans sa nature, qui nA©cessiterait dâ€™Aatre pris en compte dans le cadre de comparaisons historiques.
Evaluation and Improvements of the Level Set Method for RM Images Segmentation

We present a novel algorithm for the segmentation of bony tissues in MR images. Our approach is based on the level set algorithm. We introduce some pre-processing phases that improve image quality and segmentation performance. The technique requires no training and operates semi-automatically, requiring only the entry of a single seed point within the tissue to be segmented. The proposed approach is more robust than the other approaches present in the literature, with respect to the position of the initial seed point. The quantitative analysis of the results on a significant number of images demonstrate the effectiveness of our approach.
Fatal reactivation of hepatitis B with temozolomide.

To the Editor: Encouraging results have led to the use of temozolomide as a first-line therapy for glioblastoma.1 We report on a case of temozolomide-associated reactivation of hepatitis B, a complication that may warrant the use of prophylactic antiviral agents during treatment with this chemotherapy.2 A 65-year-old Chinese woman with a remote history of hepatitis B underwent total surgical resection of an enhancing mass in the left temporal lobe, which was diagnosed as glioblastoma. She received radiation therapy with concurrent daily temozolomide (at a dose of 75 mg per square meter of body-surface area), followed by three cycles of adjuvant .
A Review of Social Media Use in Enterprises

Social media use in organizations is proliferating and it has been proved to have huge transformative impact on organizations and on individuals. This paper provides a review of researches involving social media use in enterprises. Definition and content of enterprise social media are identified. The necessary complimentary organizational tasks in using social media technologies are discussed. Theoretical and practical implications are addressed. Keyword Enterprise social media; Use; Task
Women produce fewer but triglyceride-richer very low-density lipoproteins than men.

CONTEXT Very low-density lipoproteins (VLDL) are a major risk factor for cardiovascular disease. The concentrations of VLDL particles and VLDL-triglyceride (TG) in plasma are lower in women than men, but the mechanisms responsible for these differences are unclear. OBJECTIVE The objective of the study was to investigate the effects of sex on VLDL-TG and VLDL-apolipoprotein B-100 (apoB-100) metabolism. EXPERIMENTAL DESIGN AND MAIN OUTCOME MEASURES: We measured basal VLDL-TG and VLDL-apoB-100 kinetics by using stable isotope labeled tracers. SETTING/PARTICIPANTS Twenty-six healthy, lean subjects (13 men, aged 29+/-5 yr; 13 women, aged 28+/-6 yr) were studied in the General Clinical Research Center at Washington University School of Medicine. RESULTS VLDL-TG and VLDL-apoB-100 concentrations were less in women than men (P<0.05). The secretion rate of VLDL-TG was approximately 70% greater (P<0.05), whereas the secretion rate of VLDL-apoB-100 (i.e. VLDL particles) was approximately 20% less (P<0.05) in women than men. The molar ratio of VLDL-TG and VLDL-apoB-100 secretion rates was therefore more than double (P<0.05) in women than men. VLDL-TG plasma clearance rate was approximately 70% greater in women than men (P<0.05), whereas VLDL-apoB-100 plasma clearance rate was not different between sexes. However, VLDL-TG and VLDL-apoB-100 mean residence times in plasma were both shorter (by 45 and 25%, respectively; P<0.05) in women than men. CONCLUSIONS Increased VLDL-TG plasma clearance is responsible for lower VLDL-TG concentration, whereas decreased VLDL-apoB-100 secretion rate, combined with shorter VLDL-apoB-100 residence time in plasma, is responsible for lower VLDL-apoB-100 concentration in women than men. The greater molar ratio of VLDL-TG and VLDL-apoB-100 secretion rates suggests that the liver in women secretes fewer but TG-richer VLDL particles than the liver in men.
Postprocessing for Stochastic Parabolic Partial Differential Equations

We investigate the strong approximation of stochastic parabolic partial differential equations with additive noise. We introduce postprocessing in the context of a standard Galerkin approximation, although other spatial discretizations are possible. In time, we follow [G. J. Lord and J. Rougemont, IMA J. Numer. Anal. , 24 (2004), pp. 587-604] and use an exponential integrator. We prove strong error estimates and discuss the best number of postprocessing terms to take. Numerically, we evaluate the efficiency of the methods and observe rates of convergence. Some experiments with the implicit Euler-Maruyama method are described.
Dual Silicide SOI CMOS Integration with Low-Resistance PtSi PMOS Contacts

We demonstrate a dual silicide integration on a SOI CMOS platform with robust low-resistance PtSi PMOS contacts. Compared to NiSi, the specific contact resistivity is reduced in PtSi contacts to p-type Si and increased in contacts to n-type Si. PMOS linear and saturation drive current enhancements of 6% and 9%, respectively, were achieved with PtSi relative to baseline NiSi source/drain contacts.
A Development of Change Detection System for Urban Monitoring

This paper presents the application system of remote sensing which monitors urban objects. The system mainly aims to help public officials detect the changed areas using easy method and friendly user interface. The land cover images and the ortho-rectified aerial images which have been linked together by using geo-coordinates information are the main data to be imported and processed in the system. The modules in the system have consisted of land cover change detection and urban change detection. The latter one is for urban monitoring and planning, vector data update. Especially, urban change detection module is very useful to reduce workload of public officials performing aerial image interpretation. To be more specific, an image differencing technique and change vector technique in conjunction with transparency viewing function are employed to detect the candidates of changed area and object. Change vector technique is based on the concept of spectral angle difference of pixels in image space between co-registered images from two dates. A final product is an image layer indicating location where change occurred by overlaying of digital thematic map. We mainly present the procedure regarding change detection run by Link Viewer module.
Coronary endothelial dysfunction is associated with a reduction in coronary artery compliance and an increase in wall shear stress

Objective Endothelial dysfunction is associated with arterial stiffness in large arteries. The purpose of this study was to investigate the association between coronary endothelial dysfunction, coronary artery compliance and wall shear stress in patients with early atherosclerosis. Methods Coronary endothelial function was assessed according to responses to intracoronary acetylcholine in 120 patients without significant coronary stenosis. Acceleration of peak velocity (ACC), which is inversely related to coronary artery compliance, was derived from coronary flow velocity spectra, and wall shear rate (WSR) was calculated. Measurements were performed at baseline and after intracoronary nitroglycerin in order to eliminate the contribution of vascular smooth muscle tone to coronary artery compliance. Results In all patients, heart rate significantly increased (72±1 to 77±1 bpm, p<0.01) and mean arterial pressure decreased (97±2 to 93±1 mm Hg, p<0.01) after nitroglycerin. Coronary blood flow (CBF) and resistance were not significantly changed, but the diastolic to systolic velocity ratio increased significantly (2.15±0.08 to 5.36±0.61, p<0.01). Patients with abnormal endothelial function (n=70) had a higher WSR at baseline (559±41 vs 440±26 s−1, p<0.05) and after nitroglycerin (457±41 vs 339±29 s−1, p<0.05), and a higher ACC after nitroglycerin (3.9±0.4 vs 2.8±0.4 m/s2, p<0.05) than patients with normal function (n=50). Conclusions The current study demonstrates that intracoronary nitroglycerin does not contribute to an increase of CBF but alters the phasic coronary flow pattern. Furthermore, early coronary atherosclerosis characterised by endothelial dysfunction is associated with a decrease in coronary artery compliance and an increase in wall shear stress. Therefore, coronary wall properties are affected early in the atherosclerosis process.
Morbimortalidad de los pacientes con miocardiopatía chagásica y trasplante cardíaco. Experiencia inicial

Introduccion: La miocardiopatia chagasica durante el periodo cronico es una causa frecuente de insuficiencia cardiaca avanzada, pero la indicacion de trasplante cardiaco aun es controversial en algunos centros. Objetivos: Evaluar en estos pacientes la mortalidad, las complicaciones postrasplante, la frecuencia de reactivacion de T. Cruzi (TC) y la utilidad de su deteccion a traves de la reaccion en cadena de la polimerasa (PCR). Material y metodos: Se evaluaron 27 pacientes trasplantados desde el ano 1997: 4 pacientes chagasicos (grupo A) y 23 en el grupo control (grupo B). El analisis de PCR se realizo con empleo de la secuencia de oligonucleotico TCZ1 y TCZ2. El diagnostico de reactivacion de T. Cruzi se realizo en base a la visualizacion histopatologica de amastigotas en muestra de tejidos. Resultados: El seguimiento promedio fue de 28,75 ± 23,38 meses en el grupo A y de 28,04 ± 16,84 meses en el grupo B. La sobrevida a los 3 anos fue del 75 por ciento y el 65 por ciento respectivamente (p = 0,59). La reactivacion de TC ocurrio en los 4 pacientes chagasicos. La infeccion por CVM (p = 0,05) fue mas frecuente en el grupo A. La PCR positiva precedio en 30-60 dias a la aparicion de los sintomas en 3 pacientes y se negativizo en todos los pacientes luego del tratamiento. Conclusiones: Los pacientes trasplantados chagasicos tienen una mortalidad similar a los no chagasicos a pesar de la reactivacion de TC. La parasitemia detectada por PCR es de utilidad para el diagnostico precoz y el monitoreo terapeutico de la reactivacion de la tripanosomiasis.