Miracle-dz/UniFAR-FTUs huggingface dataset:
Root morphological plasticity and biomass production of two Chinese fir clones with high phosphorus efficiency under low phosphorus stress

Available P is the major growth-limiting factor in southern China where Chinese fir (Cunninghamia lanceolata (Lamb.) Hook. ) plantations are increasingly established. Planting P-efficient clones is a viable option to enhance productiv- ity of Chinese fir plantations. Two Chinese fir clones with high P efficiency (M1 and M4) were chosen as the research materials and their adaptive responses to low P stress were examined. The increment in root morphological traits and bio- mass production of these clones was measured by a sand culture experiment with a heterogeneous P supply. For both clones, P starvation resulted in significantly higher root surface area and root volume but not root length. For clone M4, the mean root diameter was also larger under P deficiency than under normal P supply. Interestingly, the root morphologi- cal traits varied substantially within the same root system where the starved roots had higher values for all morphological traits than the nonstarved ones. Phosphorus starvation did not affect shoot and root biomass or the root to shoot ratio, but the whole-plant biomass increment was large under P deficiency for clone M4. In conclusion, the adaptation to low P stress in these clones is attributed to increased P acquisition and utilization efficiencies.
Review on Evaluation Criteria of Machine Learning Based on Big Data

In machine learning in the context of big data, It is indispensable link for the evaluation results and indicators of prediction results. Although it is not as important as the core algorithm, it plays a role in related applications and research fields. The role of horizontal comparison of learning algorithms. The article briefly summarizes and reviews the research results of basic machine learning algorithm evaluation standards. Different evaluation methods are applied to different machine learning problems, and the trends and difficulties of machine learning evaluation methods in the future are analyzed.
Dexmedetomidine suppresses the progression of esophageal cancer via miR-143-3p/epidermal growth factor receptor pathway substrate 8 axis

Esophageal cancer is one of the fatal cancers around the world. Dexmedetomidine (DEX) is widely used during anesthesia of esophageal cancer surgery. Nevertheless, the role of DEX in the progression of esophageal cancer remains barely known. The proliferation, apoptosis and metastasis of esophageal cancer cells were detected by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, flow cytometry, transwell migration and invasion assays and Western blot assay. The expression of miR-143-3p was measured by quantitative real-time PCR in esophageal cancer tissues and cells. The binding sites between miR-143-3p and epidermal growth factor receptor pathway substrate 8 (EPS8) were predicted by Starbase online software, and the combination was verified by dual-luciferase reporter assay. The murine xenograft model was established using KYSE150 cells to verify the function of DEX in vivo. DEX inhibited the proliferation and metastasis while accelerated the apoptosis of esophageal cancer cells. The abundance of miR-143-3p was lower in esophageal cancer tissues and cells than that in paring normal tissues and normal esophageal mucosal cells Het-1A. MiR-143-3p could be induced by DEX treatment in esophageal cancer cells, and miR-143-3p also suppressed the development of esophageal cancer. EPS8 was a functional target of miR-143-3p, and it played an oncogenic role in esophageal cancer. DEX inhibited the growth of tumor via miR-143-3p/EPS8 in vivo. DEX suppressed the growth and metastasis while facilitated the apoptosis of esophageal cancer cells through upregulating the abundance of miR-143-3p and reducing the level of EPS8 in vivo and in vitro, providing promising target for the treatment of esophageal cancer.
Synthesis, Molecular Properties and MIC Studies of D-Ring Chalcone Derivatives of 20-Keto Pregnenolone

An efficient and simple synthesis of 17-chalconyl derivatives of pregnenolone and their antibacterial and antifungal evaluation is reported. The scheme involves the transformation of the starting pregnenolone to the corresponding Chalcone derivatives by the well-known Claisen-Schmidt reaction. Determination of Minimum inhibitory concentrations (MICs) is reported on these newly synthesized Chalcone derivatives of pregnenolone. The prediction of molecular properties is also discussed. Compounds showing lower MIC values also followedLipinski’s rule of 5. The results showed that the activity of the tested agents against each microbe varies due to structural differences between the microorganisms.
A Fuzzy ANP-QFD Methodology for Determining Stakeholders in Product-Service Systems Development from Ecosystem Perspective

Recently the competition between firms is transforming from “firm vs. firm” to “ecosystem vs. ecosystem”. To fulfil the personalized customer requirements for a high-quality product-service in the age of servitization and sustainability, it is difficult for an individual actor to realize it. The product-service system (PSS) is naturally an integration of product and service. The final product-service of PSS that depends on a tangible product and intangible service, calls for value co-creation of multi-stakeholders. However, most existing related works have investigated PSS from the perspective of a supply chain or network, PSS in the view of an ecosystem of multi-stakeholders lacks sufficient exploration, especially the topic on the relationship between product-service and stakeholders. To fill the gap, this paper proposed a framework for the PSS ecosystem with quality function deployment (QFD) and fuzzy analytic network process (fuzzy ANP) to determine the stakeholders by clarifying the relationship between the final integrated product-service and stakeholders. Firstly, the PSS ecosystem structure was presented, including the stakeholders. Secondly, a model with the three-stage fuzzy ANP-QFD approach to determine stakeholders was employed. Thirdly, the specific process of the three-stage approach was presented. An illustrative case study of the automobile aftermarket was presented to verify the proposed model and approach. Discussions and future directions concluded this paper.
The Lecture is Not Dead: Combined Peer Assisted Flipped Class, an Alternative to Classical Lecture in Basic Medical Education

Student engagement at lectures is declining especially at those of of basic sciences. The main method of Physiology teaching, in our settings, is the lecture. It has been increasingly challenging to employ new educational methodologies in teaching physiology for several economical and technical reasons. Our objective was to enhance lecture attendance and increasing student engagement in physiology lectures.
Dietary Effect of Artificial Zeolite on Performance, Immunity, Faecal Microflora Concentration and Noxious Gas Emissions in Pigs

A total of 48 crossbred (Landrace×Yorkshire×Duroc) pigs (2 months old; 28.38±2.62 kg body weight) were randomly assigned to either a control (basal diet) or 0.5% artificial zeolite (AZ) [basal diet + 0.5% AZ, dry matter (DM) basis] dietary treatment group in a completely randomized block design. Growth performance, immunity, muscle composition, carcass quality, faecal microflora concentration and noxious gas emissions were then investigated. No significant variation was observed in average daily gain (ADG), average daily feed intake (ADFI) or gain:feed [kg gain/kg dry matter intake (DMI)] ratio between treatments. The IgM and IgA levels remained unchanged, whereas the IgG level increased in the AZ dietary group relative to the control (P<0.05). Carcass quality, muscle composition and cholesterol level were also unaffected by AZ supplementation (P>0.05). Although AZ had no significant effect on fecal yeast and Lactobacillus spp. concentrations, a significant reduction was observed for Bacillus spp. in growing and E. coli both in growing and finishing pigs (P<0.05). Additionally, AZ supplementation led to a reduction in faecal ammonia (NH3), sulphur dioxide (SO2) and hydrogen sulphide (H2S) gases relative to the control (P<0.05). Based on these results, AZ had positive effects on faecal E. coli concentration and noxious gas emissions; however, further study with different levels of AZ to better understand its effects on growth performance of grower to finisher pigs is warranted.
A novel electrochemically active and Fe(III)-reducing bacterium phylogenetically related to Clostridium butyricum isolated from a microbial fuel cell

An obligatory anaerobic bacterium was isolated from a mediator-less microbial fuel cell using starch processing wastewater as the fuel and designated as EG3. The isolate was Gram-positive, motile and rod (2.8–3.0 μm long, 0.5–0.6 μm wide). The partial 16S rRNA gene sequence and analysis of the cellular fatty acids profile suggested that EG3 clusters with Clostridium sub-phylum and exhibited the highest similarity (98%) with Clostridium butyricum. The temperature and pH optimum for growth were 37°C and 7.0, respectively. The major products of glucose and glucose/Fe(O)OH metabolism were lactate, formate, butyrate, acetate, CO2and H2. Growth was faster at the initial phase and the cell yield was higher when the medium was supplemented with Fe(O)OH than without Fe(O)OH. These results suggest that Fe(III) ion is utilised as an electron sink. Cyclic voltammetry showed that Clostridium butyricum EG3 cells were electrochemically active. It is a novel characteristic of strict anaerobic Gram-positive bacteria.
On the Notion of Favorableness in Plant Ecology

For many years plant ecologists have espoused the notion that habitats differ in an intrinsic quality that has been called favorableness. Here I point out that the concept of favorableness is circular and counterproductive. I develop the thesis that species diversity is determined by the balance of several dynamic processes: speciation, competition, immigration, adaptation, and extinction. A simple kinetic model places each of these processes in a definite perspective. My arguments are based on the observation that widespread mesic environments commonly support vegetation containing greater species diversity than environments of more unusual character such as sand dunes, inundated depressions, bogs, mountain tops, saline soils, etc. Habitats such as these, that incorporate uncommon features and are often patchy and of small total area, are called peripheral habitats. Empirical and theoretical considerations both lead to the opinion that the pressure of competition in the species-rich communities of mesic habitats impels an adaptive outflow of species down gradient toward relatively impoverished peripheral habitats. Evolutionary difficulties involved in adapting up a competition gradient argue that the species flow from core to peripheral habitats is virtually unidirectional. Application of the kinetic model to some elementary features of the earth's geography provides a quantitative result that predicts a large and universal tropical-temperate diversity gradient. The mechanism is founded on an area-dependent model of speciation coupled to the estimated rate of environmental change with latitude. It requires no assumptions about stability, food webs, or niche packing. The last section addresses the problem of how the dimensions of plant niche space could vary between different vegetation formations and briefly discusses components of rainforest diversity.
Nuclear Receptor Research: Contributions from Latin America

1Laboratory of Immunology and Molecular Biology, Sao Leopoldo Mandic Institute and Research Center, Campinas/SP, Brazil 2Departamento de Quimica Biologica-IQUIBICEN, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires and IBYME-CONICET, Buenos Aires, Argentina 3Brazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), P.O. Box 6192, Campinas-SP, Brazil 4School of Medicine, University of Concepcion, Chile 5Departamento de Neurodesarrollo y Fisiologia, Division de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico
İmatinib ilişkili akut pankreatit: Nadir görülen bir olgu

Ilac iliskili akut pankreatit nadir gorulmekle birlikte yuksek morbitite ve mortaliteyle seyredebilir. Literaturde Imatinib kullanimina bagli gelisen pankreatit olgusuna cok az rastlanmaktadir. Kusak tarzinda akut pankreatit icin tipik karin agrisi, normal ust sinirlardan uc kat yuksek amilaz ve lipaz degerleriyle klinigimize basvuran yetmis yasindaki kadin hasta, gastrointestinal stromal tumor (GIST) nedeniyle iki yildir imatinib tedavisi almaktaydi. Akut pankreatit gelisimini aciklayacak baska bir neden saptanmayan olgumuz, literaturde Imatinib kullanimina bagli pankreatite cok ender rastlanmasi nedeniyle sunulmustur.
Microbiological Isolation of Salmonella spp. And Molecular tools for detection

This review presents an analysis about the methods to identify Salmonella spp. and the molecular studies to diagnosis this microorganism is deepened. Is believed Salmonella to be responsible of the most of cases of food-borne disease worldwide. This bacterium colonizes the most of the animals and the humans. It is not detectable in foods that has a low number of cells and the traditional methods for their detection have low specificity, sensitivity and consume long time. A systematic bibliographical search was developed in web sites, available data bases and original article. in the last year several protocols have seen developed using molecular methods to Salmonella spp. detection from clinical sample and food. The molecular detection of Salmonella spp. by PCR is more expensive than the traditional methods, but the high sensitivity and specificity that the PCR offers, the benefits to the health sector when obtaining a fast and accurate diagnosis, the relation cost benefit that grants to the productive sector allowing to release nutritional products to the market really fast way and the saving of costs, justify the implementation of that technique. The possibility of detecting microorganisms of difficult isolation in different matrices exists, using proper molecular methods and of applying them in epidemiological sanitary controls.
New Zealand Lepidoptera: Basic biogeography

Abstract The composition of the New Zealand Lepidoptera fauna is briefly described, and affinities within Tortricidae analysed. Sixty-five genera are used to indicate four possible sets of relationships, but shortcomings of taxonomic interpretations are outlined. Except for species with a wide dispersal range (some 6% of the fauna) most show affinities consonant with terrane biogeography. The panbiogeographic methodology is a potent tool in systematics, giving direction to the research effort.
SEASONAL OCCURRENCE OF INSECTS OTHER THAN HELIOTHIS SPP. FEEDING ON COTTON IN THE NAMOI VALLEY OF NEW SOUTH WALES

Data for two seasons are presented on the abundance and seasonal incidence of 17 species (6 orders) of insect found feeding on unsprayed cotton. Assessments of damage are given for several of the more important species which include Thrips imaginis, Austroasca viridigrisea, Aphis gossypii, Austracris guttulosa and Anomis flava. Population fluctuations are discussed in relation to crop phenology and insect mortality factors.
Apical abscission, a novel cell biological mechanism regulating neurogenesis

Withdrawal of differentiating neurons from the ventricle of the neural tube is a highly regulated process that is critical for the formation of normal tissue architecture and neural circuitry. We have recently reported a novel cell-biological event that mediates this process and involves local abscission of the apical cell-compartment as cells become neurons. Apical abscission takes place as adherens junctions are lost, depends on actinomyosin contractility, results in loss of apical cell polarity as well as dis-assembly of the primary cilium, and allows cell cycle exit. The molecular mechanisms mediating the series of steps underlying apical abscission are complex and inter-linked and open up many new questions. In this commentary we discuss how these mechanisms may operate and the functions of apical abscission during neurogenesis, in disease, and in other cell biological processes that involve withdrawal of cells from epithelia.
Physicochemical properties of Kalahari melon seed oil following extractions using solvent and aqueous enzymatic methods.

The physico-chemical properties of oil from Kalahari melon seed were determined following extraction with petroleum ether and aqueous-enzymatic methods. Two different enzymes Flavourzyme 1000 L and Neutrase 0.8 L were separately used during aqueous-enzymatic method. The free fatty acid, peroxide, iodine and the saponification values of the oils extracted using the methods were found to be significantly (P 0.05) difference between the oil obtained from solvent and aqueous-enzymatic extractions was observed. Enzyme-extracted oil tended to be light-coloured and more yellow in colour compared with solvent-extracted oil. The predominant fatty acids in the extracted oils were linoleic acid (62.2-63.1%), with some oleic (16.8-17.1%), palmitic (11.4-12.4%), stearic (7.5-8.1%), linolenic (0.7-1.2%) and eicosenoic (0.3%). Phenolic acids in enzyme-extracted oils were comparable to the solvent-extracted oil. The oils extracted with these two methods were differed in the composition of their phytosterol and tocopherol contents, but no significant (P > 0.05) difference between the two enzyme-extracted oils was observed.
A Green Traffic Steering Solution for Next Generation Communication Networks

In recent years, green communications and networks have drawn increasing attention from researchers and relevant industries owing to their economic and environmental benefits. In mobile networks, base stations (BSs) account for 56% of network power consumption. Hence, using green technologies in base stations would have a considerable impact on service providers’ energy bills. Consequently, researchers have investigated various green communication techniques. In this paper, we introduce a new traffic steering technique for energy conservation in next generation communication networks. By leveraging spectrum-based cell zooming techniques, the long-term evolution licensed assisted access (LTE-LAA) concept and software defined radio technology, we introduce a green traffic-steering framework that endeavors to minimize overall network on-grid power consumption and maximize aggregated throughput. Considering the time complexity of the optimum solution, we also propose a heuristic solution. We examine the proposed solution against existing solutions, and our obtained results show that the proposed framework saves up to 15% of on-grid power and increases aggregated throughput by 23%.
The Effects of Violating Hardy–Weinberg Equilibrium Assumptions on a Cluster-based Population Mixture Analysis of Steelhead Populations in Southeast Alaska

Abstract Clustering methods for population mixture analysis assign individuals probabilistically to populations based on their multilocus genotype data. An assumption of the methods is that loci satisfy Hardy–Weinberg equilibrium (HWE) conditions within populations. We observed that violating this assumption by including loci measured as deviating from HWE in baseline samples for the mixture analysis at times introduced extra structure into the mixture sample, leading to biased composition estimates and overestimation of the number of populations. Provided that samples from at least some contributing populations are available and that baseline samples can safely be assumed to come from single populations, then a conservative approach to mixture analysis would be to include only those characters that conform to HWE in the baseline samples, but this approach could result in a loss of resolving power. To address this problem, we outlined an ad hoc method of selecting loci for their use in mixture analysis ba.
Contribution of Lateral and Primary Leaves to the Development and Quality of 'Kyoho' Grape Berry

The contribution of lateral and primary leaves to the growth and quality of 'Kyoho' (Vitis vinifera × V. labrusca) berries was investigated. The total leaf area on each bearing shoot was adjusted to ca. 1500 cm2 by removing primary or lateral leaves at veraison so that the percentage of lateral leaf area (LL) beyond or distal to the cluster was : ca. 100 (100 - LL), 70 (70 - LL), 30 (30 - LL), and 0 (0 - LL) of the ca. 1000 cm2.The net photosynthetic rate (Pn) of the primary and lateral leaves on treated and intact shoots were determined.1. The berries on 100- and 70 - LL shoots ripened faster than they did on 30- and 0 - LL shoots. Berries on 100- and 70 - LL shoots accumulated total soluble solids (TSS) and anthocyanin faster than they did on 30- and 0 - LL shoots. Contrarily, titratable acidity of the berries on 100- and 70 - LL shoots decreased more rapidly than they did on 30- and 0 - LL shoots.2. During the ripening stage of the berry, the Pn of lateral leaves was faster than that of primary leaves. The Pn of basal primary leaves was significantly slower which may be responsible for the retarded ripening of berries on 0 - LL shoot.3. No significant difference was found in the leaf structure or the mineral nutrient content between primary and lateral leaves when measured before the veraison.
IgE modulation in asthma

Asthma is a chronic inflammatory disease of the airways in which allergic mechanisms, involving antibodies of the IgE class, play an important role. A humanised anti-IgE antibody that prevents the binding of IgE to its receptors has proved effective in asthma in early clinical trials. Alternative strategies for the neutralisation or suppression of IgE are being investigated and some novel compounds and coadministration regimens have been suggested. These include the provocation of host anti-IgE immune responses and the suppression of IgE synthesis, as well as the blockade of IgE receptors. Although these routes of investigation are still at an early stage of exploration, they may produce some highly novel therapeutic agents.
Seed Plant Relationships and the Systematic Position of Gnetales Based on Nuclear and Chloroplast DNA: Conflicting Data, Rooting Problems, and the Monophyly of Conifers

We investigated the systematic position of Gnetales and other seed plant groups using molecular data from 119 land plant species. More than 100 new sequences of rbcL, atpB, 26S, and 18S ribosomal DNA were analyzed together with available GenBank sequences. To evaluate thoroughly the phylogenetic information of each gene, the four data sets were analyzed both separately and combined using different character coding. We found no supported conflict between codon positions in the plastid sequences, but we found a more complex pattern, indicating conflict between transitions and transversions, within each position. Including all information, plastid data results in a “Gnetales basal” phylogeny, whereas nuclear data weakly supports anthophytes. When transitions are excluded, Gnetales associate with conifers. Our study does not answer all questions on seed plant phylogeny, but it does show conifers as monophyletic with high support, rejecting a close relationship between Gnetales and the conifer family Pinaceae. Nuclear and chloroplast data produced essentially identical phylogenies except for the position of the seed plant root, and a sister relationship between Gnetales and angiosperms could not be fully ruled out. These results strongly conflict with previously published analyses of mitochondrial data.