Miracle-dz/UniFAR-FTUs huggingface dataset:
The clarinet and clarinet playing

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Teenagers Lifestyles at Public and Private Schools: Screen Time and Physical Activity (Estilos de vida de los adolescentes en las escuelas públicas y privadas: tiempo de pantalla y actividad física)

This study aims to compare lifestyles (LS) of students at private and public schools. All schools are from Lisbon´s region (Lisbon). Five lifestyles profiles (LSP) were recognized and interpreted based on physical activity (PA) and screen time (ST). The methodology and the instruments used were adapted from the International Health Behaviour in School-aged Children (HBSC) study conducted under the auspices of the World Health Organization (WHO). Overall, the sample consists of N=2906 students of both genders averagely aged 13.6 years (SD=1.8). The results showed that in both public and private school the access and use of technological equipment’s is being democratized, but that is not true with PA practice; students of private schools are more disciplined in PA and in ST consume. Rsumen: Este estudio tiene como objetivo comparar el estilo de vida de los estudiantes de las escuelas publicas y privadas de la region de Lisboa. Cinco perfiles de estilo de vida fueron reconocidos e interpretados teniendo en cuenta la actividad fisica y el tiempo de pantalla. La metodologia y los instrumentos utilizados en este estudio son el resultado de una adaptacion del Internacional Health Beaviour in School-aged Children en ninos en edad escolar realizado bajo los auspicios de la Organizacion Mundial de la Salud. El estudio incluye N = 2906 estudiantes de ambos sexos, con una media de 13,6 anos (SD = 1,8). Los resultados mostraron que en las escuelas publicas y privadas, hay una democratizacion del acceso y uso de la tecnologia, pero no en la actividad fisica; estudiantes de colegios privados son mas disciplinados en la practica de la actividad fisica y el tiempo de pantalla. Resumo. O presente estudo pretende comparar o estilo de vida dos alunos de escolas privadas e publicas da Regiao de Lisboa. Cinco perfis de estilo de vida, foram reconhecidos e interpretados em funcao da pratica de atividade fisica e do tempo de ecra. A metodologia e instrumentos utilizados neste estudo resultam de uma adaptacao do estudo Internacional Health Beaviour in School-aged Children realizado sob a egide da Organizacao Mundial de Saude. O estudo inclui N=2906 alunos de ambos os generos, com uma media de idades de 13.6 anos (DP=1.8). Os resultados mostraram que em ambas as escolas publicas e privadas, existe uma democratizacao no acesso e na utilizacao tecnologica, mas nao na pratica de atividade fisica; os alunos das escolas privadas sao mais disciplinados na pratica de atividade fisica e no tempo de ecra.
Novel PLCG2 Mutation in a Patient With APLAID and Cutis Laxa

Background: The auto-inflammation and phospholipase Cγ2 (PLCγ2)-associated antibody deficiency and immune dysregulation (APLAID) syndrome is a rare primary immunodeficiency caused by a gain-of-function mutation S707Y in the PLCG2 gene previously described in two patients from one family. The APLAID patients presented with early-onset blistering skin lesions, posterior uveitis, inflammatory bowel disease (IBD) and recurrent sinopulmonary infections caused by a humoral defect, but lacked circulating autoantibodies and had no cold-induced urticaria, contrary to the patients with the related PLAID syndrome. Case: We describe a new APLAID patient who presented with vesiculopustular rash in the 1st weeks of life, followed by IBD, posterior uveitis, recurrent chest infections, interstitial pneumonitis, and also had sensorineural deafness and cutis laxa. Her disease has been refractory to most treatments, including IL1 blockers and a trial with ruxolitinib has been attempted. Results: In this patient, we found a unique de novo heterozygous missense L848P mutation in the PLCG2 gene, predicted to affect the PLCγ2 structure. Similarly to S707Y, the L848P mutation led to the increased basal and EGF-stimulated PLCγ2 activity in vitro. Whole blood assays showed reduced production of IFN-γ and IL-17 in response to polyclonal T-cell stimulation and reduced production of IL-10 and IL-1β after LPS stimulation. Reduced IL-1β levels and the lack of clinical response to treatment with IL-1 blockers argue against NLRP3 inflammasome hyperactivation being the main mechanism mediating the APLAID pathogenesis. Conclusion: Our findings indicate that L848P is novel a gain-of-function mutation that leads to PLCγ2 activation and suggest cutis laxa as a possible clinical manifestations of the APLAID syndrome.
To ranch or not to ranch: home on the urban range?

California ranchers in urban Alameda and Contra Costa Counties, and in rural Tehama County, were surveyed to examine effects of increasing development, land use change, and attrition of the ranching community on their commitment to ranching, and to assess land conservation program acceptability. Questions were about practices, reasons for ranching, and what influences ranching's future. Ranchers share much in common. Most enjoy ranching, "feeling close to the earth," living in a "good place for family life," and the camaraderie in the ranching community. They regularly carry out range improvements. Most believe that society is becoming "hostile to ranching. " A dislike for outsider intervention and land use control prevails. Urban ranchers cared significantly less about the fate of their ranch if sold, and feared local land use planning much more. Rural ranchers overwhelmingly wanted their ranch to remain a productive ranch even if sold. No new ranchers appeared in the urban sample for the last 10 years. As urbanization proceeds, we suggest that a point is reached where ranchers recognize the social, ecological, and economic landscape as urban and see it as no longer suitable for ranching. Expecting to sell for development, and/or expecting zoning to change to allow it, becomes the rational view. Land conservation efforts, including relatively acceptable though as yet not widespread conservation easement programs, should begin before that happens. DOI:10.2458/azu_jrm_v53i4_liffmann
Prognostic value of abnormally expressed long non-coding RNAs in patients with osteosarcoma: a meta-analysis

// Fashuai Wu 1, * , Deyao Shi 1, * , Shidai Mu 2 , Yu Huang 3 , Feng Gao 1 , Xiangcheng Qing 1 and Zengwu Shao 1 1 Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China 2 Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China 3 Department of Otorhinolaryngology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China * These authors contributed equally to this work Correspondence to: Zengwu Shao, email: profszw1962@163.com Keywords: lncRNA; osteosarcoma; prognosis; biomarker; meta-analysis Received: May 23, 2017 Accepted: December 26, 2017 Published: January 12, 2018 ABSTRACT Long non-coding RNAs (lncRNAs) contribute to progression of various cancers including osteosarcoma through abnormal regulation of cancer-related cellular processes. Recent researches have shown that various lncRNAs are abnormally expressed in osteosarcoma and associated with the prognosis. With the aim of gaining a better insight into the association between expression level of lncRNAs and prognosis of osteosarcoma, multiple databases including PubMed, Embase, Cochrane Library and Web of Science were carefully searched for available studies up to March 14, 2017. Finally, 19 publications with 1298 patients matched our inclusion criteria and were evaluated in our meta-analysis. The quality of each study was scored using the Newcastle-Ottawa Scale and studies not reaching a minimum threshold were excluded. Results of the meta-analysis demonstrated that abnormal expression level of lncRNAs predicted poor overall survival (pooled HR 3.064, 95% CI: 2.487–3.775) and event-free survival (pooled HR 2.642, 95% CI 1.759–3.970) in osteosarcoma and subgroup analysis showed consistent prognostic value. Furthermore, combining data of Cox multivariable analysis indicated that abnormal expression level of lncRNAs was an independent prognostic marker for overall survival (pooled HR 2.864, 95% CI: 2.246–3.651) in osteosarcoma patients. The clinicopathological parameters analysis further showed that abnormal expression level of lncRNAs was correlated with tumor size, tumor stage, metastasis and differentiation grade of osteosarcoma. Limitations of the meta-analysis included variation of cut-off value definition, Chinese provenance of most studies, publication bias and so on. In conclusion, this meta-analysis suggested that abnormal expression level of lncRNAs has a promising future for predicting the prognosis of patients with osteosarcoma.
Effect of Age and Periods of Rigor Mortis on Quality of Sarcoplasmic Proteins Separation from Meat’s Protein by Using Electrophoresis Technique

We were separated sarcoplasmic proteins from beef meats on 12 and 28 months ,mutton meats on 6 and 12 months and chicken meats on 25 and 40 days on rigor mortis stage and after rigor mortis stage by using electrophoresis technique. The results showed the following: Sarcoplasmic proteins differ on all types of meats below number of bands separation from it’s as differ of age of animal and stage of rigor mortis ,On beef meat proteins showed presence of 10 and 8 bands on 12 and 28 months on stage of rigor-post mortis the bands separation from sarcoplasmic, On the mutton meat we separation 10 bands of sarcoplasmic proteins on 6 and 12 months on stage of rigor-post mortis, We found 11 bands of sarcoplasmic proteinson on chicken meats on 25 and 40 days respectively.The band of phosphorylase b (PHb) and phosphorylase b kinase (PHbK) enzymes showed as one big pale band,while phosphor glucomutase) PGM), pyruvate kinase (PK), phosphoglucose isomerase) PGI), enolase (EN), creatine kinase) CK), phosphoglycerate kinase (PGAK), aldolase (ALD), glyceraldehyde phosphate dehydrogenase (GAPDH), lactate dehydrogenase (LDH), phosphoglycerate mutase) PGAM), triosephosphate isomerase (TPI) and myoglobin ( Mb ) showed as thin and pale bands. Keywords: Beef meat , mutton meat, chicken meat, meat’s protein, sarcoplasmic proteins, electrophoresis, rigor mortis
Trends in China's anthropogenic emissions since 2010 as the consequence of clean air actions

Abstract. To tackle the problem of severe air pollution, China has implemented active clean air policies in recent years. As a consequence, the emissions of major air pollutants have decreased and the air quality has substantially improved. Here, we quantified China's anthropogenic emission trends from 2010 to 2017 and identified the major driving forces of these trends by using a combination of bottom-up emission inventory and index decomposition analysis (IDA) approaches. The relative change rates of China's anthropogenic emissions during 2010–2017 are estimated as follows: −62 % for SO2, −17 % for NOx, +11 % for nonmethane volatile organic compounds (NMVOCs), +1 % for NH3, −27 % for CO, −38 % for PM10, −35 % for PM2.5, −27 % for BC, −35 % for OC, and +16 % for CO2. The IDA results suggest that emission control measures are the main drivers of this reduction, in which the pollution controls on power plants and industries are the most effective mitigation measures. The emission reduction rates markedly accelerated after the year 2013, confirming the effectiveness of China's Clean Air Action that was implemented since 2013. We estimated that during 2013–2017, China's anthropogenic emissions decreased by 59 % for SO2, 21 % for NOx, 23 % for CO, 36 % for PM10, 33 % for PM2.5, 28 % for BC, and 32 % for OC. NMVOC emissions increased and NH3 emissions remained stable during 2010–2017, representing the absence of effective mitigation measures for NMVOCs and NH3 in current policies. The relative contributions of different sectors to emissions have significantly changed after several years' implementation of clean air policies, indicating that it is paramount to introduce new policies to enable further emission reductions in the future.
PI forecast with or without de-clustering: an experiment for the Sichuan-Yunnan region

Abstract. Pattern Informatics (PI) algorithm uses earthquake catalogues for estimating the increase of the probability of strong earthquakes. The main measure in the algorithm is the number of earthquakes above a threshold magnitude. Since aftershocks occupy a significant proportion of the total number of earthquakes, whether de-clustering affects the performance of the forecast is one of the concerns in the application of this algorithm. This problem is of special interest after a great earthquake, when aftershocks become predominant in regional seismic activity. To investigate this problem, the PI forecasts are systematically analyzed for the Sichuan-Yunnan region of southwest China. In this region there have occurred some earthquakes larger than MS 7.0, including the 2008 Wenchuan earthquake. In the analysis, the epidemic-type aftershock sequences (ETAS) model was used for de-clustering. The PI algorithm was revised to consider de-clustering, by replacing the number of earthquakes by the sum of the ETAS-assessed probability for an event to be a "background event" or a "clustering event". Case studies indicate that when an intense aftershock sequence is included in the "sliding time window", the hotspot picture may vary, and the variation lasts for about one year. PI forecasts seem to be affected by the aftershock sequence included in the "anomaly identifying window", and the PI forecast using "background events" seems to have a better performance.
Flocculation and nanofiltration processes with insight of fouling phenomena for the treatment of olive mill wastewater

Olive oil production is one of the main agriculture activities in many Mediterranean countries and it usually produces huge quantities of wastewaters. The management, treatment and safe disposal causes serious environmental issues. The adverse characteristic properties of OMW, which are the main responsible of their hazardous disposal, generally do not permit the treatment only by biological processes. Combined innovative processes should be adopted to remove the various organic and inorganic hazardous compounds from these wastewaters. Among the typical olive mill wastewater (OMW) treatments the most widely used are: drying / evaporation, forced evaporation, thermal treatment, electrocoagulation, composting, lagooning, adsorption, powdered activated carbon, sand filtration, membrane filtration, precipitation / flocculation, distillation, electrolysis, co-composting, advanced oxidation processes (AOPs). To define an efficient pre-treatment and to overcome major obstacles of membrane treatment (fouling), economic organic coagulant has been tested. Chitosan, a natural linear bio-polyaminosaccharide, is obtained by alkaline deacetylation of chitin. The main purpose of this study was to investigate the effects of chitosan as coagulant aid to reduce phenols content, COD and TOC in OMW, in addition to control membranefouling, which is used in the sequential step of the treatment. A conventional jar test apparatus was employed for the flocculation tests followed by photo catalysis and membrane treatment includes Nano Filtration process by means of a pilot-scale plant.
Design of 3 D Space Following Positioning System Based on ZigBee

The research on positioning system and spatial alignment is a big topic. In this paper, we proposed a design (that) studies two issues. One is the study of range positioning algorithm based on ZigBee communication system. The other one is spatial alignment platform which is controlled with two servos. Hardware and software control system was realized, which also consists of two parts, ZigBee network positioning system and automatic orientation platform.
Real Coded Biogeography-Based Optimization for Environmental Constrained Dynamic Optimal Power Flow

The optimization is an important role in wide geographical distribution of electrical power market, finding the optimum solution for the operation and design of power systems has become a necessity with the increasing cost of raw materials, depleting energy resources and the ever growing demand for electrical energy. In this paper, the real coded biogeography based optimization is proposed to minimize the operating cost with optimal setting of equality and inequality constraints of thermal power system. The proposed technique aims to improve the real coded searing ability, unravel the prematurity of solution and enhance the population assortment of the biogeography based optimization algorithm by using adaptive Gaussian mutation. This algorithm is demonstrated on the standard IEEE-30 bus system and the comparative results are made with existing population based methods.
Examining the Comorbidity of Language Impairment and Attention-Deficit/Hyperactivity Disorder

Language impairment (LI) and attention-deficit/hyperactivity disorder (ADHD) are 2 relatively common developmental disorders that have been shown to have high rates of co-occurrence in a number of studies, and this phenomenon is also commonplace in the experience of many clinicians. Understanding this comorbidity, therefore, is central to building coherent taxonomic systems within the field of speech–language pathology for clinical and theoretical reasons. As we review the current literature we consider which models of comorbidity are relevant to the study of LI and ADHD (see Tomblin & Mueller, 2012, for a review of the models that are discussed). Finally, we present original data on the comorbidity of LI and ADHD from a large population-based sample that has been studied over the last 2 decades in the state of Iowa. We evaluate how this contributes to current understanding of these disorders.
The Effect of HIV and Art on the Development of Hypertension and Type 2 Diabetes Mellitus

Diabetes mellitus and hypertension [DM] are among the major causes of morbidity and mortality among people living with human immunodeficiency virus [PLHIV]. Diabetes mellitus alone is associated with morbidities that consequently reduce life expectancy and quality of life, and causes demoralising complications inclusive of ischaemic heart disease, stroke, blindness and peripheral vascular disease. Hypertension is an important and treatable cause of cardiovascular morbidity and mortality. It is an independent risk factor for myocardial infarction, chronic kidney disease ischemic and haemorrhagic stroke, heart failure and premature death. HIV infection is associated with morbidities that consequently reduce life expectancy and quality of life. There is a perceived link between HIV infection and DM and hypertension. This is a scoop review of studies on the link between HIV and DM and hypertension, that is, both epidemiologic and biological evidence to date. The literature review shows that the incidence and prevalence of type 2 diabetes [T2DM] is higher among PLHIV on ART compared to the HIV negative population. Being infected by human immunodeficiency virus (HIV) is implied to trigger an inflammatory response that, in turn, results in insulin resistance, a risk for T2DM. HIV is linked to hypertension through alterations in triglycerides, T cells and angiotensin II as well as the aggressive use of ART. The roll out of antiretroviral therapy (ART), as means to combat HIV, has benefits for PLHIV, inclusive of increased survival and living longer; yet older age is associated with hypertension and T2DM. The side effects of ART and long term use of ART are implicated in increasing the risk of T2DM among PLHIV. The co-occurrence of HIV, hypertension and T2DM in developing countries presents an overload to the burden of diseases because these countries are already experiencing high prevalence rates of HIV thereby complicating the health status of the population. Notwithstanding the contrasting research reports on the link between HIV, hypertension and DM hypertension and DM among PLHIV is a cause for concern, and there is a need for more studies, particularly in areas most hit by HIV.
Design and Implementation of Anti-phishing Authentication System

For phishing problems and its essential characteristics, the authentication protocol of anti-phishing based on two-direction, two-factor, and interaction is proposed, and its safeties are investigated. For PKI security infrastructure and B/S technology model under Internet, an interactive authentication mechanism based on special custom image and client program is designed and implemented. The method is universal to authenticate any server on Internet. It is a new solution of anti-phishing.