Miracle-dz/UniFAR-FTUs huggingface dataset:
HG-14CLINICAL, RADIOGRAPHIC, AND HISTOLOGIC CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY

Children with diffuse intrinsic brainstem glioma (DIPG) have a median survival of less than 1 year despite radiation ± chemotherapy. The International DIPG Registry, a collaborative effort among researchers in North America and Australia has enrolled 395 patients with data for over 900 patients committed from 35 institutions. Among the 395 patients, 32 long-term survivors (LTS) (overall survival [OS] ≥2 years) have been identified. Preliminarily, we report clinical, radiographic, and histologic data for 75 of 395 patients, including the 32 LTS and 43 in the comparison (C) group. On central radiographic review, 5 were deemed not to represent DIPG (3 LTS and 2 C). Median age at diagnosis for LTS and C groups was 5.5 and 6.1 years, respectively. Fifty-seven percent of LTS had >6 weeks between onset of symptoms and diagnosis versus 28% for the comparison group (p < 0.05). Incidence of signs and symptoms at diagnosis (cranial nerve, cerebellar, or pyramidal) was similar in both groups. All patients, except 3 LTS, underwent radiation at diagnosis; all but 6 received adjunct chemotherapy. Median OS was 28.4 and 10.8 months for the LTS and C groups, respectively. Two patients (1 LTS) had an H3.3K27M mutation and 2 (1 LTS) had an H3.1K27M mutation. Biology data from 25 other patients from autopsy (n = 12) or biopsy (n = 13) are under analysis. Presence of enhancement on diagnostic imaging was associated with poorer survival (p = 0.02). There was no significant difference in radiographic evidence of hemorrhage, necrosis, diffusion restriction, or tumor size between LTS and C groups. Preliminary data in children with DIPG suggest that LTS have a longer duration of presenting signs and symptoms and less often display radiographic evidence of enhancement at diagnosis. Complete clinical, radiographic, and biology (where available) data on all 395 patients enrolled are currently being analyzed and will be presented.
Teaching Spatial Thinking in Design Computation Contexts: Challenges and Opportunities

A new generation of design computation systems affords opportunities for new design practices. This calls for potentially new teaching requirements in design education, in particular the development of the requisite spatial thinking skills. In this chapter, the authors review the pertinent literature, followed by two case examples that illustrate how spatial thinking was taught in two undergraduate design courses. The authors’ experiences suggest that early exposure to spatial thinking concepts, coupled with practice using computational design tools in the context of a project, can significantly help students to improve the skills necessary to design in a digital environment. Through the use of team projects, the authors discovered the potential variances in design representations when students switched between digital and physical modeling. They propose further research to explore the spatial processes required in computational design systems and the implications for design education.
Op weg naar competentiegericht opleiden : een onderzoek naar innovatiediffusie bij de Fontys Lerarenopleiding Tilburg

Het omvormen van een op kennisoverdracht georiknteerde lerarenopleiding naar een competentiegerichte lerarenopleiding is een complexe vernieuwingsoperatie. Op vele niveaus moeten er vernieuwingen worden gerealiseerd en er zijn veel participanten. Het onderzoek heeft zich gericht op de verschillende deelnemers aan het veranderingsproces: de studenten, de docenten en de mentoren op de werkplek. Er is nagegaan in hoeverre deze deelnemers in staat waren om hun rol in het vernieuwingsproces adequaat in te vullen.
WORK PERFORMANCE LIMITATIONS POST ANASTROZOLE TREATMENT FOR WOMEN WITH BREAST CANCER

Due to early diagnosis and advancements in breast cancer treatments, an increasing number of women are living longer after treatment. Conversely, many women’s experiences of extended life involve enduring long-term effects of breast cancer treatments possibly including pain, fatigue, decreased energy, sensory, and motor function, lymphedema, cognitive impairments, osteoporosis, nausea, and sleeping difficulties (American Cancer Society, 2013; Brach et al., 2004; Jenkins, Shilling, Fallowfield, Howell, & Hutton, 2004; Pullens, De Vries, & Roukema, 2010). Aromatase inhibitors, including anastrozole, have proven efficacy for adjuvant therapy in postmenopausal women with breast cancer (Nabholtz, 2008; Rinaldi, 2013). Adjuvant therapy may have negative effects on cognitive functioning (Bender et. al., 2007; Nattinger et al., 2013). Cognitive, physical, and affective impairments contribute to the likelihood of increased work problems. Largely, the condition, treatments, and consequential effects may alter body functions/structures, activities, and community participation. In theory, anastrozole treatment may increase the likelihood of work problems. Work after a cancer diagnosis is highly desirable for individuals on a person, social, and economic level, ultimately contributing to quality of life, dignity, self-esteem, and purpose (Steiner, Cavender, Main, & Bradley, 2004). Women with breast cancer commonly report work-related concerns including job loss, demotion, unwanted changes in tasks, problems with the employer/co-workers, personal changes in attitudes to work and diminished physical capacity (Brisson, Dubois, Fraser, Lauzier, & Maunsell, 1999). The purpose of this study was to examine the effects of the anastrozole breast cancer treatment, as it relates to the individuals’ abilities to function at work. Through critical analysis of data from the Anastrozole Use In Menopausal Women (AIM) study, this study found that overall, the anastrozole group reported more work problems than the control group overtime. Pain emerged as a confounding variable that supports reason for further investigation of the effects and role of pain due to breast cancer and/or treatment, specifically as it pertains to work performance. Knowing that more individuals with breast cancer are surviving and are continuing to work or returning to work, additionally considering that treatment effects and residual symptoms are often present, this population likely would benefit from vocational rehabilitation support and services.
Canvis emocionals en l'envelliment

El present article enumera i descriu els diferents aspectes i canvis afectius que poden donar-se durant el proces d�envelliment de l�esser huma. L�article preten descriure les formes i peculiaritats dels diferents trastorns afectius, durant l�envelliment, amb la finalitat de poder facilitar un correcte i apropiat diagnostic com a primer pas per a un adequat tractament. Aquesta descripcio es realitza des de l�analisi dels diferents factors que es produeixen i influeixen en l�aparicio dels canvis afectius. A continuacio s�especifica com son les caracteristiques dels trastorns afectius en l�envelliment, contemplant els trastorns depressius, els trastorns ansiosos i els trastorns bipolars, les diferents formes de manifestar-se i les peculiaritats de cada entitat en les persones grans. Al llarg de tot l�article tenen una important consideracio de les consequencies que els trastorns afectius generen en la familia i en l�entorn social. De la mateixa manera es te present com els canvis afectius influeixen en l�evolucio de les malalties previes ja existents. Per altra banda, es posa de manifest la dificultat, per una part, i la important necessitat, per una altra, d�un correcte diagnostic quan aquest pot estar solapat i emmascarat pels simptomes dels trastorns afectius i de les demencies.
Seek control of hard disk drives based on final-state control taking account of the frequency components and the magnitude of control input

In this paper, the authors develop a new design method of the reference trajectory for hard disk drives. The control input is assumed to be generated through zero-order-hold and the reference trajectory is designed so that the frequency component of the control input is minimized over the desired frequency points. Input constraints can also be incorporated into the design. Simulation results are shown to evaluate the effectiveness of the proposed method.
The Truth (with Jokes)

It's time to set the record straight. Al Franken - nemesis of the neocons and the only comedian to have performed at Abu Ghraib, as far as we know - brings us the truth (with jokes) about the people who run our lives. Here are the facts about double-dealing and dirty tricks at the highest levels. Here too is the true story of the election, starring Three Horsemen of the Republican Apocalypse: Fear, Smear and Queers. Not to mention the god-fearing Republican figures caught up in sex tours and gambling scandals. You couldn't make it up .
Stochastic language models for music information retrieval

La recuperacion de informacion musical (Music Information Retrieval, MIR) es un area de investigacion interdisciplinar que pretende resolver muchos de los problemas que plantea el acceso a grandes bases de datos multimedia, en concreto aquellas con contenido musical, ya sea en formato simbolico (MIDI) o audio, Un problema especialmente importante es la organizacion e indexacion automatica de los datos, ya que realizar estas tareas de forma manual requeriria un gran esfuerzo que puede ser inabarcable para muchas personas e instituciones. Uno de los descriptores mas relevantes que se pueden obtener a partir de una cancion para su organizacion automatica es el estilo musical, ya que el estilo es uno de los campos mas usados por la gente para acceder a bases de datos y catalogos musicales. En esta tesis se estudia hasta que punto se puede determinar el estilo de una obra musical basandose unicamente en la informacion contenida en su partitura, usando para ello tecnicas de reconocimento de patrones aplicadas sobre secuencias melodicas y armonicas.
How the Body Shapes the Way We Think: A New View of Intelligence (Bradford Books)

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Regulatory Mechanisms of Chondrogenesis and Implications for Understanding Articular Cartilage Homeostasis

Studies of chondrogenesis and embryonic limb development offer a wealth of knowledge regarding signals that regulate the behavior of chondrocytes. Many such chondrogenic regulators are upregulated in osteoarthritis-affected chondrocytes, suggesting a role in pathogenesis. Yet, some of the same factors also support adult articular cartilage ho- meostasis, and enhance neo-cartilage tissue formation in experimental models. In this review, we summarize many of the important regulatory mechanisms involved in chondrogenesis and examine how their disruption may contribute to func- tional changes in articular cartilage during osteoarthritis or aging.
The Appeal of the Moving Picture

Here is the reason for the popularity of moving pictures: they help keep people from going batty. Most popular and professional writers on the mass media of communication say that people go to the movies or listen to radio dramas to "get away from their problems. " This is the idea of "escape," and it is the most common explanation for movie attendance. People want to be transported into "another world" according to this theory, and because this "other world" has no relation to their own world people feel emotional relief when they observe it. The theory is worth more discussion than it has received. If people want from the mass media a "world" which has no relation to their own, the content presented is relatively unimportant. If the audience goes to the movies to find something there that is related to their own lives, then it's a different matter altogether. A survey of the opinions of social scientists on this subject was given by Joseph T. Klapper in The Effects of Mass Media: A Report to the Director of the Public Library Inquiry. In a chapter with the imposing title, "The Functions and Effects of Escapistic
Littérature et monde rural

[eng] Writers have often been inspired by country life. But the hierarchy according to which literary works are ranked by historians is not based on the same criteria as those used by literary critics. As important as Balzac's Paysans and Zola's La Terre, are second-rank novels by Rene Bazin and Ernest Perochon. The historian can find there concrete data about weather, information about the techniques in use, remarks about social relations. Yet he must be careful about that kind of bias which is often caused by the quest for an artistical effect, and also pay attention to those ideological deviations which push the writer either to blacken or to embellish a crude reality. [fre] Si la campagne a souvent inspire les ecrivains, la hierarchie de notre sujet n'est pas celle de la critique litteraire. Aux Paysans de Balzac et a La Terre de Zola, il faut joindre les œuvres de second rang, comme celles de Rene Bazin et d'Ernest Perochon. L'historien peut y trouver des donnees concretes sur le temps, des informations sur les techniques, des observations sur les rapports sociaux. Il doit toutefois se tenir en garde contre les deformations qu'entraine la recherche d'un effet artistique, comme contre les deviations ideologiques, qui tantot noircissent, tantot embellissent la realite brute.
Archaeology between Ballia and Robertsganj in Uttar Pradesh; Notes on Some Early Historic Routes of the Area

L'auteur presente quelques voies commerciales anciennes situees en Uttar Pradesh depuis les premiers siecles de notre ere environ. Il passe en revue les villages ou les monticules archeologiques qui peuvent temoigner de l'importance du trafic le long de ces routes, les decrivant et les datant dans la mesure du possible.
Durchflusszytometrische Kontrolle von MSC-Produkten im Rahmen der Herstellung als ATMP für klinische Prüfungen

Zusammenfassung Ex vivo expandierte mesenchymale Stroma-/Stammzellen (MSC) werden mittlerweile aus zahlreichen Geweben isoliert und in klinischen Studien der regenerativen Medizin und der immunmodulatorischen Therapie eingesetzt. Die bisher existierenden Definitionen der MSC sind zwar sehr allgemein gefasst, Kriterien zur Verwendung von MSC in unterschiedlichen klinischen Einsatzgebieten bedürfen jedoch ggf. einer angepassten Spezifikation. Wir stellen hier die Vorgehensweise der durchflusszytometrischen Charakterisierung von MSC zum Einsatz in klinischen Prüfungen zur Knochenregeneration vor und diskutieren die Notwendigkeit, Spezifikationen für MSC in Abhängigkeit von ihrem jeweiligen Einsatzgebiet zu definieren.
Searching beyond reason

McDermott argues that “many inferences which seem so straightforward that they must be deductions turn out to have nondeductive components,” and claims to have found Hayes himself bending the rules of logic. A careful reading of OFL, however, does not reveal any logical error. Given the axioms developed in OFL, Hayes sketches the following proof Assume a falling history begins at time t , whose bottom is the free top of a tub (a container, all of whose other sides are solid). Therefore, the amount of water in the tub is increasing (at time r ) ; furthermore, “so long as the tap keeps running it will go on increasing. ” That is, for all t ’ > t , if the falling history extends from t to f’, then the containment history (of the water in the tub) between t and t’ is an “increasing. ” The argument is impeccable and relies on all the axioms about how containers hold liquids. The next step in the argument is a bit poorly worded. The paper states, “Let us suppose that eventually the bath is full,” and a few lines later concludes, “The bath will overflow. ” At this point we have assumed
Imagining Arab womanhood : the cultural mythology of veils, harems, and belly dancers in the U.S.

Excavating Orientalist Images of Arab Womanhood Traveling Orientalism: U.S. Echoes of a French Tradition Dancing the Hootchy Kootchy: The Rhythms and Contortions of American Orientalism Selling Little Egypt: The Commodification of Arab Womanhood Veiled Intentions: The Cultural Mythology of Veils, Harems, and Belly Dancers in the Service of Empire, Security and Globalization
Prevention and Treatment of the Complications of Diabetes Mellitus

Diabetes mellitus is a chronic disease characterized by hyperglycemia and by complications that include microvascular disease of the eye and kidney and a variety of clinical neuropathies.1 Although diabetes is also associated with premature macrovascular disease, this review is limited to a discussion of retinopathy, nephropathy, and neuropathy. The pathophysiology of these complications of diabetes was recently reviewed in the Journal. 1 The specific association of microvascular disease and neuropathy with diabetes and the relation of the two complications to the duration of diabetes suggest that they are linked to hyperglycemia or a concomitant metabolic abnormality. The Diabetes Control and Complications .
The prevalence of Hepatitis B virus infection in an HIV-exposed paediatric cohort from the Western Cape, South Africa

3 OPSOMMING . 5 ACKNOWLEDGEMENTS . 7 TABLE OF CONTENTS . 10 LIST OF ABBREVIATIONS AND SYMBOLS . 13 LIST OF TABLES . 15 LIST OF FIGURES . 17 CHAPTER ONE: INTRODUCTION. 18 CHAPTER TWO: LITERATURE REVIEW . 21 2.1 STRUCTURE OF HBV . 21 2.2 LIFE CYCLE AND REPLICATION . 25 2.3 EPIDEMIOLOGY OF HBV WITH EMPHASIS ON SOUTH AFRICA . 27 2.4 DISTRIBUTION OF GENOTYPES AND THEIR CLINICAL SIGNIFICANCE. 29 2.5 NATURAL HISTORY OF HBV INFECTION . 32 2.6 MODES OF TRANSMISSION . 38 2.7 PREVENTION OF HBV INFECTION IN INFANTS . 41 CHAPTER THREE: MATERIALS AND METHODS . 44 3.1 ETHICAL APPROVAL . 44 3.2 SAMPLE AND DATA COLLECTION . 44 3.3 SCREENING PROCESS AND FOLLOW-UP OF POSITIVE SAMPLES . 45 3.4 SEROLOGICAL TESTING . 46 3.4. 1 SCREENING FOR HBsAg AT SCREENING STAGE AND FOLLOW UP . 46 3.4. 2 CONFIRMATION TEST FOR HBsAg POSITIVES . 48 3.4. 3 HBeAg TESTING OF HBsAg POSITIVE SAMPLES . 50 3.4. 4 AntiHBe TESTING OF HBsAg-POSITIVE SAMPLES . 52 3.4. 5 AntiHBc TESTING OF ALL FOLLOWED-UP SAMPLES . 54 Stellenbosch University http://scholar.sun.ac.za
Wide swath, high range resolution imaging with MIMO-SAR

The paper describes a novel approach combining space filtering with bandwidth synthesis to achieve wide swath and high range resolution, Firstly, Low PRF is adopted to achieve unambiguous wide swath; then space filters is used to remove azimuth ambiguity; finally sub-band signals are combined into a wider band signal to achieve high range resolution. Simulation results are provided to show the validity of the proposed method. (6 pages)
Some communication complexity issues in asynchronous algorithms

Summary form only given. The author has studied an asynchronous version of the Bellman-Ford algorithm for computing the shortest distances from all nodes in a network to a fixed destination. It is known that this algorithm has (in the worst case) exponential (in the size of the underlying graph) communication complexity. The author has obtained results indicating that its expected (in a probabilistic sense) communication complexity is actually polynomial, under some reasonable probabilistic assumptions. He has shown that a recently introduced method for asynchronous simulation with rollback contains the Bellman-Ford algorithm as a special case, and he has deduced that the rollback method also has exponential communication complexity. The author has also investigated whether (under certain probabilistic assumptions and/or modifications of the simulation algorithm) the communication complexity becomes polynomial. <<ETX>>
Stereoscopic high dynamic range imaging

Two modern technologies show promise to dramatically increase immersion in virtual environments. Stereoscopic imaging captures two images representing the views of both eyes and allows for better depth perception. High dynamic range (HDR) imaging accurately represents real world lighting as opposed to traditional low dynamic range (LDR) imaging. HDR provides a better contrast and more natural looking scenes. The combination of the two technologies in order to gain advantages of both has been, until now, mostly unexplored due to the current limitations in the imaging pipeline. This thesis reviews both fields, proposes stereoscopic high dynamic range (SHDR) imaging pipeline outlining the challenges that need to be resolved to enable SHDR and focuses on capture and compression aspects of that pipeline. The problems of capturing SHDR images that would potentially require two HDR cameras and introduce ghosting, are mitigated by capturing an HDR and LDR pair and using it to generate SHDR images. A detailed user study compared four different methods of generating SHDR images. Results demonstrated that one of the methods may produce images perceptually indistinguishable from the ground truth. Insights obtained while developing static image operators guided the design of SHDR video techniques. Three methods for generating SHDR video from an HDR-LDR video pair are proposed and compared to the ground truth SHDR videos. Results showed little overall error and identified a method with the least error. Once captured, SHDR content needs to be efficiently compressed. Five SHDR compression methods that are backward compatible are presented. The proposed methods can encode SHDR content to little more than that of a traditional single LDR image (18% larger for one method) and the backward compatibility property encourages early adoption of the format. The work presented in this thesis has introduced and advanced capture and compression methods for the adoption of SHDR imaging. In general, this research paves the way for a novel field of SHDR imaging which should lead to improved and more realistic representation of captured scenes.