Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparison of anesthesia with sevoflurane-N_2O and midazolam-remifentanil in low-birth-weight premature infants undergoing diode laser photocoagulation

Aim: The present study aimed to compare anesthesia with sevoflurane-N2O and midazolam-remifentanil in terms of hemodynamic parameters and safety in low-birth-weight (LBW) premature infants undergoing diode laser photocoagulation (DLP) for retinopathy of prematurity (ROP). Materials and methods: A total of 91 infants undergoing DLP for ROP were enrolled in this study. All of the infants were established with LBW (
Esmolol in the management of epinephrine- and cocaine-induced cardiovascular toxicity.

Many treatments have been suggested for management of life-threatening hypertension, tachycardia, and myocardial ischemia associated with hyperadrenergic states (1-6). The availability of the short-acting p,-selective blocking drug esmolol has allowed more precise control of catecholamine surges without fear of overtreatment. We report a case in which esmolol was beneficial in the perioperative management of epinephrineand cocaine-induced cardiovascular toxicity. To our knowledge, this case represents the first reported use of this agent in this situation.
Psychopathy, Sexual Deviance, and Recidivism Among Sex Offenders

The relationships between psychopathy, sex offender type, sexual deviance, and recidivism were examined in 156 federally incarcerated sex offenders in a 10-year follow-up study. The rapists and mixed offenders demonstrated higher psychopathy scores than did the child molesters and incest offenders (total scores and Factor 2 scores on the Psychopathy Checklist—Revised [PCL-R]; R. D. Hare, 2003). Factor 1 scores were approximately the same in all groups. The PCL-R was a weak predictor of sexual recidivism but consistently predicted nonsexual violent recidivism and general recidivism (mainly via Factor 2). Sexual deviance measured by a structured rating scheme predicted sexual recidivism. Sexual deviance, so rated, was a stronger predictor of sexual recidivism than psychopathy but the two interacted significantly suggesting that psychopathy could potentiate sexual recidivism. Although psychopathy was a strong positive predictor of general nonsexual recidivism, sexual deviance was inversely related, and no interaction was observed between psychopathy, sexual deviance, and nonsexual recidivism.
Alterations of grey matter asymmetries in adolescents with prelingual deafness: a combined VBM and cortical thickness analysis.

PURPOSE Prelingual deafness has been shown to lead to brain reorganization as demonstrated by functional parameters, but anatomical evidences still remain controversial. The present study investigated hemispheric asymmetry changes in deaf subjects using MRI, hypothesizing auditory-, language- or visual-related regions after early deafness. METHODS Prelingually deaf adolescents (n = 16) and age- and gender-matched normal controls (n = 16) were recruited and hemispheric asymmetry was evaluated with voxel-based morphometry (VBM) from MRI combined with analysis of cortical thickness (CTh). RESULTS Deaf adolescents showed more rightward asymmetries (L < R) of grey matter volume (GMV) in the cerebellum and more leftward CTh asymmetries (L > R) in the posterior cingulate gyrus and gyrus rectus. More rightward CTh asymmetries were observed in the precuneus, middle and superior frontal gyri, and middle occipital gyrus. The duration of hearing aid use was correlated with asymmetry of GMV in the cerebellum and CTh in the gyrus rectus. Interestingly, the asymmetry of the auditory cortex was preserved in deaf subjects. CONCLUSIONS When the brain is deprived of auditory input early in life there are signs of both irreversible morphological asymmetry changes in different brain regions but also signs of reorganization and plasticity which are dependent on hearing aid use, i.e. use-dependent.
Report from the IAB Workshop on Routing and Addressing

This document reports the outcome of the Routing and Addressing Workshop that was held by the Internet Architecture Board (IAB) on October 18-19, 2006, in Amsterdam, Netherlands. The primary goal of the workshop was to develop a shared understanding of the problems that the large backbone operators are facing regarding the scalability of today's Internet routing system. The key workshop findings include an analysis of the major factors that are driving routing table growth, constraints in router technology, and the limitations of today's Internet addressing architecture. It is hoped that these findings will serve as input to the IETF community and help identify next steps towards effective solutions. Note that this document is a report on the proceedings of the workshop. The views and positions documented in this report are those of the workshop participants and not of the IAB. Furthermore, note that work on issues related to this workshop report is continuing, and this document does not intend to reflect the increased understanding of issues nor to discuss the range of potential solutions that may be the outcome of this ongoing work. This memo provides information for the Internet community.
rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

The signal transduction pathway leading to the activation of the transcription factor NF-kappaB remains incompletely characterized. We demonstrate that in HeLa cells, transient expression of a constitutively active mutant of the small GTP-binding protein rac1 (V12rac1) leads to a significant increase in NF-kappaB transcriptional activity. In addition, expression of a dominant-negative rac1 mutant (N17rac1) inhibits basal and interleukin 1beta-stimulated NF-kappaB activity. Gel shift analysis using nuclear extract prepared from HeLa cells infected with a recombinant adenovirus encoding N17rac1 (Ad.N17racl) showed reduced levels of cytokine-stimulated DNA binding to a consensus NF-kappaB binding site. We demonstrate that rac proteins function downstream of ras proteins in the activation of NF-kappaB. In addition, V12rac1 stimulation of NF-kappaB activity is shown to be independent of the ability of rac proteins to activate the family of c-jun amino-terminal kinases. In an effort to further explore how rac proteins might regulate NF-kappaB activity, we demonstrate that expression of V12rac1 in HeLa cells or stimulation with cytokine results in a significant increase in intracellular reactive oxygen species (ROS). Treatment of cells with either of two chemically unrelated antioxidants inhibits the rise in ROS that occurs following V12rac1 expression as well as the ability of V12rac1 to stimulate NF-kappaB activity. These results suggest that in HeLa cells, rac1 regulates intracellular ROS production and that rac proteins function as part of a redox-dependent signal transduction pathway leading to NF-kappaB activation.
NADZOR BANAKA I STABILNOST BANKARSKOG SUSTAVA

Bankarstvo je djelatnost koja, izravno i neizravno, utjece na dobrobit svake druge djelatnosti i gospodarstva kao cjeline. S druge strane, bankarstvo je djelatnost preuzimanja rizika imanentnih prirodi financijskih institucija. Bankarstvo danas prolazi kroz opsežne promjene u funkcijama i oblicima. Nastanak gigantskih banaka kroz konsolidacije i akvizicije, rastuca konkurencija nebankovnih financijskouslužnih poduzeca, internacionalizacija financijskih tržista, multipliciranje usluga, promjene propisa i deregulacija, kontinuirane inovacije u informacijskoj tehnologiji i automatizaciji su promjene uvjetovane sve snažnijim trendom globalizacije. Bankarstvo zahtjeva i ljudske i tehnicke vjestine za razumijevanje rizicnih obilježja okruženja banke, identifikaciju i klasifikaciju rizika, njihovo mjerenje, kontrolu te uspostavu procedura i instrumentarija za smanjenje izloženosti rizicima kako bi mogucnost nastanka gubitaka bila svedena na minimum. Da bi se taj cilj kontinuirano ostvarivao u bankarstvu je neizbježna sve veca međudržavna suradnja kako u reguliranju tako i superviziji banaka i to od uvjeta za osnivanje i poslovanje banaka do trenutka prestanka poslovanja banke.
Análise critico reflexiva sobre a influência das características da envolvente na hierarquia dos utilizadores da informação financeira: uma abordagem ao caso português a partir da teoria da contingência

RESUMO: A contabilidade, tomando por base o objectivo a que preside, existe para satisfazer necessidades de um grupo de utilizadores com interesses diversos e por vezes contraditorios. Mas se em teoria o seu objectivo e generico e abstracto na pratica parece nao ser bem assim, na medida em que a evidencia empirica disponivel aponta para a necessidade de fazer opcoes. E, pois, dentro deste quadro que se realiza o presente trabalho, cujo objectivo e desenvolver uma analise critica e reflexiva sobre a influencia das caracteristicas da envolvente, nomeadamente as da estrutura empresarial, na definicao das politicas contabilisticas para responder a necessidades muito especificas que emergem da envolvente. A linha metodologica e qualitativa, assente numa reflexao teorica, e a tecnica de recolha de dados o inquerito por questionario. O trabalho realizado permitiu concluir que a preparacao da informacao financeira implica apreciacoes e opcoes, tornando-a muito dependente da envolvente onde as entidades actuam. PALAVRAS-CHAVE: Contabilidade financeira; Estrutura empresarial; Utilizador da informacao financeira; Sistema de informacao financeira.
Spotting handwritten words and REGEX using a two stage BLSTM-HMM architecture

In this article, we propose a hybrid model for spotting words and regular expressions (REGEX) in handwritten documents. The model is made of the state-of-the-art BLSTM (Bidirectional Long Short Time Memory) neural network for recognizing and segmenting characters, coupled with a HMM to build line models able to spot the desired sequences. Experiments on the Rimes database show very promising results.
Iron Balances in Infant Nutrition

ABSTRACT. Iron balance studies were performed in 17 full term male infants from their 3rd until their 17th week of life. The balance studies were made in the infant's home and comprised 5 periods with an interval of 3–4 weeks, each consisting of three 24‐hour collections. Ten infants were breast‐fed, 3 received an adapted infant formula (P1, iron content 1.1 mg/l) and 4 were given the same formula enriched with iron, copper and zinc (P2, iron content 10.35 mg/l). From the 3rd to the 17th week of life the breast‐fed infants got a mean iron intake of 0.2 mg/kg body weight ×3 days and they retained 0.09 mg/kg b.w. ×3 days. The P1 group received 0.48 and 0.47 mg/kg b.w. ×3 days and retained ‐0.01 and ‐0.5 mg iron/kg b.w. ×3 days, while the P2 group had an intake from 5.04 to 6.38 mg b.w. ×3 days and retained between 1.13 and 3.66 mg iron/kg b.w. ×3 days. Comparing the 3 groups it can be concluded that the P1 group retained definitely less iron than the breast‐fed group, whereas the P2 group retained 12 to 40 times more iron than the breast‐fed babies.
Behavioral description of quantum V and V+ gates to design quantum logic circuits

Quantum gates which are represented by unitary matrices have potentials to implement reversible logic circuits. V and V+ gates are two well known quantum gates which are used to synthesize the reversible logic circuits. In this paper we have used behavioral description of these gates, instead of unitary matrix description, to synthesize reversible logic circuits. By this method, V and V+ gates are shown in the truth table form. Results show that bigger circuits with more number of gates can be synthesized using proposed method. Some benchmarks of reversible logic circuits are also optimized and compared to other works.
Write performance of heads with 2.1-Tesla CoNiFe pole

We examined the write performance of heads with a CoNiFe/NiFe composite write pole. The saturation induction B/sub s/ of the CoNiFe film was 2.1 T (21 kG). The CoNiFe layer thickness was typically 0.5-0.6 /spl mu/m, and the rest of the write pole was composed of Ni/sub 80/Fe/sub 20/. The dual high B/sub s/ layer structure with the CoNiFe films on both sides of the write gap gave excellent overwrite performance. It was over 30 dB for a medium that had a high coercivity of 560 kA/m (7.0 kOe).
The effect of backrest angles on discomfort caused by fore-and-aft back vibration.

The effect on discomfort of the frequency and the backrest angle of x-axis (fore-and-aft) vibration of backrest have been studied. The method of adjustment was employed to obtain contours of equivalent comfort for three types of rigid backrests, whose surface were vertical, inclined 20 degrees and 40 degrees from vertical. Eighteen subjects were required to adjust test vibration over the frequency range 2-80 Hz to produce discomfort equivalent to that caused by 10 Hz 0.25 m/s2 r.m.s. sinusoidal reference vibration for each backrest. The direction of vibration was perpendicular to backrest surface. Results shows that the sensitivity at 20 and 40 Hz on inclined backrests is significantly about 1.4 to 1.5 times greater than that on a vertical backrest (p < 0.01) but there is no significant difference between the two contours for inclined backrests. The contour for a 'vertical' backrest obtained in this experiment agrees with the contour calculated from the frequency weighting factors for x-axis back vibration, Wc, in ISO2631-1, but the contours for inclined backrests do not agree with the contour well.
Immunologic responsiveness in phenylketonuria.

Recent studies have demonstrated that administration of the amino acid phenylalanine (L-phenylalanine) to experimental animals will result in partial suppression of antibody responses to diptheria toxoid and sheep red blood cells and will also cause partial suppression of homograft rejection. 1,2 Since patients with phenylketonuria may have markedly elevated serum phenylalanine levels, the present study was undertaken to determine if immunologic responsiveness is impaired in humans with this disorder. Antibody responses following immunization with diphtheria toxoid and Escherichia coli Vi antigen, the development of delayed hypersensitivity following administration of BCG vaccine, and serum immunoglobulin levels were studied in phenylketonuric children on normal diets and on standard low-phenylalanine diets. Similar studies were performed in nonphenylketonuric controls. Materials and Methods Subjects. — Four groups of subjects (Table 1) were used for this study: Group A. — Children with phenylketonuria (PKU currently on a standard low-phenylalanine diet with biochemical controls. Group B. — Control
Optimisation de Fonctions de Contraste en Séparation de Sources

La Separation de Sources consiste a retrouver un jeu de M signaux independants appeles sources a partir de l'observation de N de leurs melanges. Il existe de nombreuses methodes de separation qui sont pour la plupart basees sur les statistiques d'ordre superieures. Ces methodes permettent d'exploiter l'hypothese d'independance des sources. Dans ce cadre nous avons considere le cas de la separation de sources basee sur l'optimisation de fonctions de contraste dans un cas de melange lineaire purement spatial. Nous proposons d'abord deux nouvelles familles de contrastes regroupant comme cas particulier des contrastes existants. Puis nous determinons la solution optimale dans le cas deux sources pour ces deux familles de contrastes. Cela nous permet finalement de proposer deux algorithmes, qui constituent alors deux generalisations d'algorithmes classiques. Ensuite, nous etudions l'optimisation d'un contraste sous contrainte, afin de proposer des algo¬rithmes ne necessitant pas. Comme dans le cas precedent de blanchiment prealable des donnees. Deux familles de methodes directes d'optimisation sous contrainte sont considerees : les methodes duales et les methodes directes. Cela nous permet en outre de developper des algorithmes utilisant les notions de Lagrangien, de penalisation et de projection sur la contrainte. Des simulations informatiques illustrent le comportement des algorithmes proposes.
Mesure des anisotropies de polarisation du fond diffus cosmologique avec l'interféromètre bolométrique QUBIC

La quete des modes B de polarisation du fond diffus cosmologique est aujourd'hui un des enjeux scientifiques majeurs de la cosmologie observationnelle. Observer les modes B constituerait une sonde directe de la periode d'inflation. La detection de ce signal, attendu a un niveau tres faible, represente un defi technologique. Il necessite non seulement une sensibilite importante, mais aussi une soustraction des signaux d'avant-plans et un tres bon controle des effets systematiques. Dans ce but, un important travail experimental est en cours. L'instrument QUBIC est une des experiences dediees a la detection des modes B. Il est base sur une technologie novatrice : l'interferometrie bolometrique, qui permet de reunir les avantages d'un imageur en terme de sensibilite et ceux d'un interferometre en terme de controle des effets systematiques. Dans ce manuscrit, nous expliquerons le concept de l'instrument et nous decrirons ses composantes. Nous nous concentrerons sur le combineur optique de l'instrument dont nous expliciterons le role et nous presenterons une methode developpee afin d'etudier l'impact des aberrations optiques et des desalignements des composantes du combineur sur la sensibilite globale de l'instrument. Nous introduirons une procedure de calibration specifique a l'interferometrie bolometrique basee sur la redondance des lignes de base : la self-calibration. Cette methode permet de calibrer les parametres qui caracterisent completement l'instrument simultanement et pour chaque canal cornet-bolometre-pointage. Finalement, nous presenterons les dernieres avancees des simulations sur la fabrication des cartes avec l'instrument QUBIC et sur l'estimation des spectres de puissance.
Effect of thiouracil on free amino acids in the blood plasma of chicks.

Abstract LEVELS of free amino acids as determined in the blood plasma of chicks can be quite variable even though the chicks are fed similar diets and are of the same breed, sex and age (Shao and Hill, 1967; Hill and Olsen, 1963). An unusually high level of lysine and threonine observed in an experiment in which blood was sampled under conditions of extremely high summer temperature (Hill and Olsen, 1965), prompted us to consider the possibility that the metabolic rate of the bird at the time of sampling might influence plasma amino acid levels. As a test of this hypothesis we measured the plasma amino acids following administration of thiouracil at a level which might be presumed to lower metabolic rate (Singh and Shaffner, 1950; McCartney and Shaffner, 1950, 1949; Shaffner and Andrews, 1948). Although the observations in the present paper did not support the above hypothesis they are believed .
Sphingosylphosphorylcholine and Lysophosphatidylcholine Are Ligands for the G Protein-coupled Receptor GPR4*

Sphingosylphosphorylcholine (SPC) and lysophosphatidylcholine (LPC) are bioactive lipid molecules involved in numerous biological processes. We have recently identified ovarian cancer G protein-coupled receptor 1 (OGR1) as a specific and high affinity receptor for SPC, and G2A as a receptor with high affinity for LPC, but low affinity for SPC. Among G protein-coupled receptors, GPR4 shares highest sequence homology with OGR1 (51%). In this work, we have identified GPR4 as not only another high affinity receptor for SPC, but also a receptor for LPC, albeit of lower affinity. Both SPC and LPC induce increases in intracellular calcium concentration in GPR4-, but not vector-transfected MCF10A cells. These effects are insensitive to treatment with BN52021, WEB-2170, and WEB-2086 (specific platelet activating factor (PAF) receptor antagonists), suggesting that they are not mediated through an endogenous PAF receptor. SPC and LPC bind to GPR4 in GPR4-transfected CHO cells withK d/SPC = 36 nm, andK d/LPC = 159 nm, respectively. Competitive binding is elicited only by SPC and LPC. Both SPC and LPC activate GPR4-dependent activation of serum response element reporter and receptor internalization. Swiss 3T3 cells expressing GPR4 respond to both SPC and LPC, but not sphingosine 1-phosphate (S1P), PAF, psychosine (Psy), glucosyl-β1′1-sphingosine (Glu-Sph), galactosyl-β1′1-ceramide (Gal-Cer), or lactosyl-β1′1-ceramide (Lac-Cer) to activate extracellular signal-regulated kinase mitogen-activated protein kinase in a concentration- and time-dependent manner. SPC and LPC stimulate DNA synthesis in GPR4-expressing Swiss 3T3 cells. Both extracellular signal-regulated kinase activation and DNA synthesis stimulated by SPC and LPC are pertussis toxin-sensitive, suggesting the involvement of a Gi-heterotrimeric G protein. In addition, GPR4 expression confers chemotactic responses to both SPC and LPC in Swiss 3T3 cells. Taken together, our data indicate that GPR4 is a receptor with high affinity to SPC and low affinity to LPC, and that multiple cellular functions can be transduced via this receptor.
Severe Local Storms Forecasting

Abstract Knowledge of severe local storms has been increasing rapidly in recent years as a result of both observational studies and numerical modeling experiments. This paper reviews that knowledge as it relates to development of new applications for forecasting of severe local storms. Many of these new applications are based on physical understanding of processes taking place on the storm scale and thus allow forecasters to become less dependent on empirical relationships. Refinements in pattern recognition and severe weather climatology continue to be of value to the operational severe local storms forecasters, however. Current methodology for forecasting severe local storms at the National Severe Storms Forecast Center is described. Operational uses of new forecast applications, new “real-time” data sources (such as wind profilers and Doppler radars), and improved numerical model products are discussed.