Miracle-dz/UniFAR-FTUs huggingface dataset:
S 1 P 2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate

Szczepaniak WS, Pitt BR, McVerry BJ. S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate. Am J Physiol Lung Cell Mol Physiol 299: L137–L145, 2010. First published April 30, 2010; doi:10.1152/ajplung.00233. 2009. —Vasoactive properties of sphingosine 1-phosphate (S1P) have been demonstrated by many investigators to vary in systemic vascular beds. These variations appear to reflect differential S1P receptor expression in the vasculature of these tissues. Although S1P has been demonstrated to enhance endothelial barrier function, induce airway hyperresponsiveness, and modulate immune responses in the lung, the pulmonary vasomotor effects of S1P remain poorly defined. In the present study, we sought to define the vasoregulatory effects of S1P in the pulmonary vasculature and to elucidate the underlying mechanisms operative in effecting the response in the intact lung. S1P (10 M) increased pulmonary vascular resistance (PVR) by 36% in the isolated perfused mouse lung. S1P-induced vasoconstriction was reduced by 64% by concomitant administration of the Rho-kinase inhibitor Y27632 (10 M). Similarly, the S1P response was attenuated by 50% after S1P2 receptor antagonism (JTE-013; 10 M) and in S1P2 receptor null mice. In contrast, S1P3 receptor antagonism (VPC23019; 10 M) had no effect on the contractile response to S1P. Furthermore, we confirmed the role of Rho-kinase as an important regulator of basal vasomotor tone in the isolated perfused mouse lung. These results suggest that S1P is capable of altering pulmonary vascular tone in vivo and may play an important role in the modulation of pulmonary vascular tone both in the normal lung and under pathological conditions.
Proposal and evaluation of reactively loaded inverted F antenna for cognitive wireless communication

In this paper, we propose a frequency-tunable compact antenna to enable cognitive wireless communication. Planar type inverted F antennas corresponding to some wireless service frequency bands are combined with a common feed rod. By loading variable diodes in the closed loops of each inverted F antenna, the reactance for each varactor diode can be controlled independently with DC voltage. We demonstrated an antenna design that achieved an impedance matching less than three for VSWR in the three frequency bands of the UHF band, the 1.92 - 2.17 GHz band, and the 5.15 - 5.35 GHz band.
Is the topical application of oestrogen cream an effective intervention in girls suffering from labial adhesions?

A 4-year-old girl presents with low-grade pyrexia and dysuria. A urine dipstick test shows positive results for leucocytes and nitrite, suggesting urinary tract infection. On examination, you notice partial adherence of the vulval labia minora. Her mother reports that the girl has intermittently had discomfort in the genital area over the last year. While waiting for the results of the urine microscopy, you remember that one of your colleagues has mentioned treating labial adhesions with oestrogen creams in the past. You wonder whether there is good evidence to support their use in this condition. In a girl with labial adhesions (patient), is oestrogen cream (intervention) an effective treatment to induce labial separation (outcome)? Cochrane Library using the terms “labial adhesion AND treatment”, “labial adhesion AND management” and “labial adhesion and oestrogen/estrogen” as well as three alternative terms for labial adhesion (“labial fusion”, “labial agglutination”, “synechia vulvae”) in combination (AND) with “treatment”, “management”, “oestrogen” and “estrogen”. No relevant results. PubMed (1975–2006) using the same search terms (no limits set). Search date: 21/05/06. Search outcome: a total of 207 matches for all searches combined—147 articles in total. Only three were relevant.1–3 In addition, we retrieved and evaluated publications that were cited as references in the three articles found in the initial literature search. This method identified two more relevant articles.4–5 Labial adhesion, also termed labial agglutination, labial fusion and synechia vulvae, is not a rare condition and has been reported to occur in up …
A wide dual-band circularly polarized antenna for GPS high-precision survey

In this work, a wide dual-band circularly polarized antenna for GPS high-precision survey is proposed and investigated. This antenna is realized by two stacked microstrip patches. Each patch is fed by four ports with orthogonal distribution on the plane, and the four ports are stimulated by separate signals which have same amplitude but 90 degree phase-shift in a clockwise direction. The present antenna shows excellent features, including compact size, wide dual-band, and satisfied radiation gain, achieving circular polarization easily, which make it a promising candidate prospect in the field of high precision survey.
Compact Folded Dipole With Embedded Matching Loop for Universal Tag Applications

A coin-shaped folded dipole is proposed for designing a UHF tag that can be placed in free space and on metal. The proposed tag antenna is compact ( $0.095\lambda )$ and low in profile (1.6 mm). It is composed of a matching loop, which is encircled by two patch-shaped radiating arms, forming an embedded structure that has high compactness. Slots are etched in the radiators for fine-tuning the resonant frequency. An equivalent circuit has also been obtained for analyzing the impedance characteristics of the tag antenna across the frequency range, and it is found that the radiating element itself is capacitive and inclusion of the matching loop is essential for making the tag antenna inductive for achieving good matching with the chip. Simulation and experiment have been conducted to study the charateristics of the proposed tag antenna. When tested in free space with an Effective Isotropic Radiated Power (EIRP) input power of 3.28 W, the tag antenna is able to reach a maximum read range of 5.2 m, but it reduces to 1.8 m when placed on metal. Also, the resonant frequency of the proposed tag antenna is found to be stable and not affected much by its backing object.
KNOWLEDGE, ATTITUDE AND PRACTICE OF HOUSE KEEPING STAFF REGARDING BIOMEDICAL WASTE MANAGEMENT

Medical care is vital for our life and health, but the waste generated from medical activities represents a real problem of living nature and human world. In order to make its disposal and treatment successful, it is vital that the various healthcare professionals working at the hospitals have correct knowledge, attitudes and practices regarding biomedical waste management(1). Objective: The present study was aimed to assess the knowledge, attitude and practice of housekeeping staff regarding biomedical waste management Methodology: The research design adopted for the present study was Descriptive research Design . The study was conducted among sixty six subjects of selected hospital. Informed consent was obtained from study participants and the data were collected by self report method using socio personal proforma , semi structured questionnaire Result: The findings shows more than half of the subject had good knowledge ,positive attitude,healthy practices towards biomedical waste management and significant correlation was found between knowledge ,attitude and practices. Summary: On the whole, the knowledge,attitudes and practices among the participants was fair.
DATA MINING AND SOCIAL NETWORKING SITES: PROTECTING BUSINESS INFRASTRUCTURE AND BEYOND

Social networks are not new to the IT landscape, having morphed from bulletin boards and chat rooms to the desktop and mobile application tools such as Facebook, Twitter and LinkedIn which millions of people use on a daily basis. These free and easy to use cloud based applications provide users and companies a continuous stream of valuable communication, offering businesses a broader reach and frequency of their branding messages. Unfortunately, in concert with businesses and private users, hackers have joined in seeking to fulfill their own malicious agenda by exploiting information posts in social networks.
Corporate social responsibility practices of transnational corporations: Examples from Turkey and Italy

As an open system and a social institution, companies’ responsibilities have gone beyond the provision of shareholder wealth. Today, companies are expected to conform the principles of good corporate citizenship and corporate governance, and disclose corporate activities in an accountable, honest and transparent manner. In this context, sustainability reporting is an important tool for communicating organizational performance related to economic, social and environmental issues with respect to corporate social responsibility (CSR) practices. The aim of this study is to analyze the annual corporate social responsibility or sustainability reports published by transnational corporations in the context of the triple bottom line (TBL) approach and to determine the similarities and differences of CSR practices applied in Turkey and Italy. The annual corporate sustainability or corporate social responsibility reports of the transnational corporations listed in Forbes CSR ranking were examined to identify the CSR practices in Turkey and Italy. Content analysis and the triple bottom line dimensions developed by Ho and Taylor (2007) and Rondinelli (2006) were implemented to evaluate the CSR reports. The results of the study indicate that the corporations compose their sustainability reports with reference to the triple bottom line approach. Data of environmental issues like water and energy consumption, disposal of waste and CO2 emissions are given in absolute numbers. Reports also include projections about goals in percentage and tables. Corporate social responsibility projects in Turkey and Italy enabled us to identify and analyze the manner renewable energy, waste disposal, use of global resources, intercultural problems, entrepreneurship and healthy eating issues are being handled in a comparative perspective. © 2013European Journal of Research on Education by IASSR.
Multinational Corporations: Conflicts and Controls

Starting with the end of the Second World War there has been a remarkable growth in multinational corporations. The current public attention to these corporations is due, at least in part, to their recent expansion and to the increasingly significant role that they are playing in both national economies and the world economy. The greatest corporate growth and national legal development have both taken place in the developed-country context. However, with growing world economic interdependence and growing sophistication of the economies of less-developed countries, the experience of developed countries is sure to be of relevance to all planners, whatever the level of their nation's economic development.This article considers some of the types of tensions and conflicts which the existence and operations of multinational corporations create. The article begins with a brief description of the rapid growth of multinational corporations. Section II analyzes types of conflict, which for analytical purposes can be divided into three basic groups: (a) conflict between multinational corporations and host countries, (b) conflict between multinational corporations and home countries, and (c) conflicts between host countries and home countries engendered by the activities of multinational corporations. Section III describes the present pattern of controls and regulations in the important areas of export (and import) control, securities regulation, antitrust regulation, and taxation. In the final section, we give our suggestions for regulating and controlling multinational corporations in the international arena.
Human Mood Detection For Human Computer Interaction

In this paper we propose an easiest approach for facial expression recognition. Here we are using concept of SVM for Expression Classification. Main problem is sub divided in three main modules. First one is Face detection in which we are using skin filter and Face segmentation. We are given more stress on feature Extraction. This method is effective enough for application where fast execution is required. Second, Facial Feature Extraction which is essential part for expression recognition. In this module we used Edge Projection Analysis. Finally extracted features vector is passed towards SVM classifier for Expression Recognition. We are considering six basic Expressions (Anger, Fear, Disgust, Joy, Sadness, and Surprise)
Arenoviruses in Vero Cells: Ultrastructural Studies

Thin-section electron microscopy was carried out on Vero green monkey kidney cell cultures infected with some viruses of the newly constituted arenovirus group. Junin, Machupo, Amapari, Pichinde, Parana, Tamiami, and Latino viruses were morphologically identical and indistinguishable from lymphocytic choriomeningitis virus, the prototype virus of the group. Virus particles were round, oval, or pleomorphic, 60 to 280 nm in diameter, and matured via budding from plasma membranes. Most characteristically, particles contained various amounts of homogeneous, 20- to 25-nm, dense granules; these granules in large masses also formed distinctive intracytoplasmic inclusions. In negative-contrast preparations from infected Vero cell culture supernatant fluids, several of the viruses appeared as pleomorphic membrane-bound forms with rather pronounced surface projections. Most particles were between 90 and 220 nm in diameter, although some reached 350 nm in their longest dimension. Internal structure was not resolved by negative-contrast electron microscopy. All observations supported the current delineation of a distinct arenovirus group.
The Impact of Alternative Assets on the Role of Direct Property in Australian Mixed-Asset Portfolios

Abstract Australian superannuation funds have increased their allocations to the alternative assets in recent years; this includes private equity, infrastructure, hedge funds and commodities. This raises the issue of whether this increased allocation to these alternative assets impacts on the strategic role and allocation of direct property in the Australian mixed-asset portfolio, due to the potential increased competition between these assets. This paper assesses the risk-adjusted performance and portfolio diversification benefits of direct property and various alternative assets over 1995–2009 and their role in optimal mixed-asset portfolios. While direct property is still seen to play a key role in the portfolio, direct property plays a less significant role in the portfolio when the alternative assets are included. In particular, Australian unlisted infrastructure and listed infrastructure are seen as key alternative assets across a significant portion of the portfolio risk spectrum. This is seen as validating the investment strategy of Australian superannuation funds who have significant exposure to the infrastructure sector.
A Semi-Parametric Model of Market Conduct: The Case of Banking Sector Competition In Jamaica 1990-2004

This paper examines the eff ect of financial market liberalization/deregulation on bank competition across types of banks in Jamaica between 1990 and 2004. Bank conduct is of utmost importance since driving up (down) loan (deposit) interest rates could stymie economic growth. The analysis employs the Asymptotically Ideal Model (AIM) of Barnett and Jonas (1983) and Bresnahan's (1982) measure of market conduct. Detailing the evolution of conduct reveals predatory pricing, and that increased concentration dominated the equalization in reserve requirements which characterized the period. This suggests anti-competitive behavior, however, the welfare eff ects remain ambiguous.
Use of the Harm Susceptibility Model to Prioritize Risks in an Acute Geriatric Hospital

ishes with age. There are several possible explanations for this. First, with changes to the sensory and neuromuscular system and poorer ability to walk and perform a cognitively demanding task, perhaps more practice is needed for sleep to produce off-line improvements with advancing age. Second, changes in sleep quality and quantity with advancing age might explain age-related decline in sleepdependent off-line learning, although the findings of the current study indicated that sleep quantity and quality did not differ between young, middle-aged, and older individuals. Third, changes in sleep architecture with advancing age might explain the decline in sleep-dependent off-line motor skill learning in middle-aged and older adults. Sleep spindles are thought to drive off-line motor skill learning, so fewer sleep spindles with advancing age may explain the decline in sleep-dependent off-line learning in middle-aged and older adults, although the design of this study did not allow this possibility to be examined. Thus, mechanisms explaining sleep-dependent off-line learning in middle-aged and older adults are still unclear and warrant further investigation. Evidence that middle-aged and older adults benefit from sleep to enhance performance of a functional motor task but to a lesser degree than young adults has significant implications for rehabilitation. Individuals frequently learn functional skills during rehabilitation. It may be that clinical outcomes could be improved if healthcare professionals considered the effect of sleep (or lack of sleep) on learning these new skills. Better walking ability could increase older adults’ ability to walk safely and improve function in their home as well as access to the community. Furthermore, because many of the comorbidities that present with older age affect sleep quality and could consequently impair the sleep-dependent learning process, healthcare professionals should assess sleep quality and educate middle-aged and older adults on methods to improve sleep quality. The effect of medications on sleep should also be considered.
Exploration of the Audit Independence

Different from the two kinds of audit requirements proposed by agency theory, the practical audit mode needs to guarantee the audit independence. But the stakeholders of the audit business make current protection measures for the independence of the audit from their own view. From the systems perspective, we suggest on the basis of considering the audit process that: (1) we should improve the information transparency before the manager and the auditor make the audit contract by the construction of enterprises. (2) we should strengthen the publicity when we hire or dismiss the audit firm. (3)the audit association provide professional service for the board of directors, in particular the board of audit committee. (4)we should introduce a third party arbitration to resolve accounting divergence between the auditor and manager (5)we should expand the channels of supervision, and strengthen the execution of the punishment. Index Terms - Audit independence, Systematic process, The third party
Towards an ultra-low power, high density and non-volatile Ternary CAM

Due to rapidly expanding networking industry demands, there is a corresponding need for high speed search capability, reduced power consumption and data masking within Content Addressable Memory (CAM) devices. These devices are used in applications requiring fast database searches. Image or voice systems, computer and communication systems are all CAM users. CAM have advantages in term of performance over other memory search algorithms. This is due to the simultaneous comparison of the desired information against the entire list of pre-stored entries. CAM have arrays designed to enable stored values to be located quickly by comparing input data to memory data to locate a match. This paper presents a design of a 18 Kb non-volatile Ternary Content Addressable Memory (TCAM) integrating Magnetic Random Access Memory (MRAM) devices. Magnetic Ternary Content Addressable Memory (MTCAM) can simplify conventional TCAM cell from sixteen transistors to 2 MRAM cells and 6 transistors. Furthermore, such device is intrinsically non volatile, e.g. power-failure-resistant. The MRAM cells are used both to store the information and to compare it (search) to the inputted data like an XOR logic function, whilst the CMOS part is used to detect and amplify the cell state.
Social media practices in SME marketing activities: A theoretical framework and research agenda

This paper describes the importance of understanding the social media practices of small and medium-sized enterprises in the context of their marketing activities development. By bringing together literature on SME marketing, social media and dynamic capabilities, the authors argue that SMEs develop, change and evolve their marketing activities by acquiring market intelligence through social media use. This article examines literature, and proposes a conceptual model to guide research in exploring these activities. The proposed model can also assist SMEs in developing and refining their offline and online marketing practices.
Effects of dietary methionine on productivity, reproductive performance, antioxidant capacity, ovalbumin and antioxidant-related gene expression in laying duck breeders

Abstract The study investigated whether dietary methionine (Met) affects egg weight and antioxidant status through regulating gene expression of ovalbumin (OVAL), nuclear factor erythroid 2 like 2 (Nrf2) and haem oxygenase 1 (HO-1) in laying duck breeders. Longyan duck breeders (n 540, 19 weeks) were randomly assigned to six treatments with six replicates of fifteen birds each. Breeders were fed diets with six Met levels (2·00, 2·75, 3·50, 4·25, 5·00 and 5·75 g/kg) for 24 weeks. The egg weight (g), egg mass (g/d), feed conversion ratio, hatchability, 1-d duckling weight, albumen weight, albumen proportion and OVAL mRNA level improved with dietary Met levels, whereas yolk proportion decreased (P<0·05). The weight of total large yellow follicles increased linearly (P<0·001) and quadratically (P<0·05) with dietary Met concentration, and their weight relative to ovarian weight showed a linear (P<0·05) effect. Dietary Met level had a linear (P<0·05) and quadratic (P<0·001) effect on the gene expression of glutathione peroxidase (GPX1), HO-1 and Nrf2, and quadratically (P<0·05) increased contents of GPX and total antioxidant capacity (T-AOC) in liver of duck breeders. In addition, maternal dietary Met enhanced gene expression of GPX1, HO-1 and Nrf2, increased contents of GPX and T-AOC and reduced carbonylated protein in the brains of hatchlings. Overall, dietary Met concentration affected egg weight and albumen weight in laying duck breeders, which was partly due to gene expression of OVAL in oviduct magnum. A diet containing 4·0 g Met/kg would achieve optimal hepatic GPX1 and Nrf2 expression, maximise the activity of GPX and minimise lipid peroxidation.
Teaching medical students using role play: Twelve tips for successful role plays

Engaging students in role play promotes active learning. Planned and structured role plays can be used to deliver components of the curriculum in clinical rotations of a medical programme. Role plays are most effective if learning objectives are defined, and the cases are challenging. All students should be involved and ground rules should be set. Allow adequate time for the role play, feedback and reflection. Let the students enjoy themselves. This paper provides 12 tips to create a meaningful learning experience for students using role play.
Automatización del almacén y surtido en la distribución de productos de

Las tecnologias de la informacion y de las comunicaciones pueden suponer una fuente de ventajas competitivas para la empresa distribuidora, si bien implica incurrir en importantes costes. En el presente trabajo tratamos de identificar los factores que caracterizan a las empresas que invierten en dichas tecnologias para automatizar la gestion de su almacen y, en concreto, la relacion entre el grado de automatizacion y el surtido de productos de la empresa.