Miracle-dz/UniFAR-FTUs huggingface dataset:
Performance analysis of downlink user selection in multiuser MIMO system

This paper is based on a multiuser MIMO system with K single-antenna receivers and M antennas at the base station. The number of users which can be serviced at the same time is limited, the users need to be selected when there are more users than transmit antennas. The sum capacity of two kinds of user selection algorithm: Zero-Forcing beamforming with user selection (ZFS) and greedy Zero-Forcing Dirty-Paper algorithm (gZF-DP) is analyzed in Rayleigh fading channel. And we explore how their parameters affect their performance. Comprehensive simulation is also done to compare the performance of the same strategy with the ideal or estimated channel information. The simulation results indicate that when channel information is accurate, gZF-DP can gain more sum rate. While ZFS can save computational resource and gain matched sum rate when channel information is not so accurate. Channel information plays a very important role in the user selection and the precoding matrix design.
Quercetin protects against radiocontrast medium toxicity in human renal proximal tubular cells

Radiocontrast media (RCM)‐induced acute kidney injury (CI‐AKI) is a major clinical problem whose pathophysiology is not well understood. Direct toxic effects on renal cells, possibly mediated by reactive oxygen species, have been postulated as contributing to CI‐AKI. We investigated the effect of quercetin on human renal proximal tubular (HK‐2) cells treated with the radiocontrast medium (RCM) sodium diatrizoate. Quercetin is the most widely studied flavonoid, and the most abundant flavonol present in foods. It has been suggested to have many health benefits, including angioprotective properties and anti‐cancer effects. These beneficial effects have been attributed to its antioxidant properties and its ability to modulate cell signaling pathways. Incubation of HK‐2 cells with 100 μM quercetin caused a decrease in cell viability and pre‐treatment of HK‐2 cells with 100 μM quercetin followed by incubation with 75 mgI/ml sodium diatrizoate for 2 hr caused a decrease in cell viability which was worse than in cells treated with diatrizoate alone. However, further incubation of the cells (for 22 hr) after removal of the diatrizoate and quercetin caused a recovery in cell viability in those cells previously treated with quercetin + diatrizoate and quercetin alone. Analysis of signaling molecules by Western blotting showed that in RCM‐treated cells receiving initial pre‐treatment with quercetin, followed by its removal, an increase in phosphorylation of Akt (Ser473), pSTAT3 (Tyr705), and FoxO3a (Thr32) as well as an induction of Pim‐1 and decrease in PARP1 cleavage were observed. Quercetin may alleviate the longer‐term toxic effects of RCM toxicity and its possible beneficial effects should be further investigated.
Impaired Orientation in Acute Stroke: Frequency, Determinants, and Time-Course of Recovery

Orientation is an indicator of general intellectual function and is defined as the ability to report time, place, and personal data. Our knowledge of orientation in acute stroke is sparse. We examined the frequency of impaired orientation in acute stroke, its determinants, and recovery in 653 consecutive patients with acute stroke who were not unconscious and who were without severe aphasia. Prospective assessments of orientation and stroke severity were done by the Scandinavian Neurologic Stroke Scale at the time of acute admission and hereafter weekly until the end of rehabilitation. Impaired orientation was found in 23% of the patients on acute admission and in 12% of the survivors after completed rehabilitation. A stationary level of orientation was achieved by 80% of the patients within 2 weeks and by 95% within 6 weeks. A multiple linear regression analysis found neurological score (B = 0.027, SE(B) = 0.003), age (B = –0.013, SE(B) = 0.003), and comorbidity (B = –0.023, SE(B) = 0.078), but not sex, prior stroke, handedness, or side of stroke lesion to be significant independent determinants of orientation score on acute admission. Lesions involving the anterior and medial thalamus and/or any of the cerebral lobes were associated with impaired orientation. In conclusion, impaired orientation is frequent in acute stroke and the time-course of recovery is similar to what has been found in other neuropsychological impairments with the major part of recovery early after stroke onset.
Individual Variation in the Perception of Vowels: Implications for a Perception-Production Link

Abstract A scaling experiment using dyadic comparisons of vowel pairs was performed to determine if significant perceptual variation existed on an individual level and whether such variation could be correlated with differences among subjects in their production of vowels. Subjects were required to scale six separate sets of vowel stimuli. Each stimulus set consisted of the 36 possible dyads from the vowel set /i, I, ε, æ, a, Λ, o, Æ, u/. Analysis of the resulting data indicated that significant individual perceptual variation was present which could be seen as a function of perceptual structure differences between the subjects and not merely error variance. In addition, such variations were related to aspects of each subject’s acoustic vowel space – indicators of tongue height and advancement during vowel articulation. These results were interpreted as suggesting a link between perception and production.
Acquired central hypoventilation following Listeria monocytogenes rhombencephalitis

Acquired central hypoventilation syndrome (CHS) is a rare cause of respiratory failure. We report a case of acquired CHS, diagnosed several years after Listeria monocytogenes (LM) rhombencephalitis. In 1993, a 46-year-old woman presented to our Sleep Clinic with poor sleep, nocturnal choking episodes and daytime fatigue. She denied habitual snoring and hypersomnolence. Her medical history was unremarkable except for severe LM rhombencephalitis in 1977. At that time, the patient had been hospitalised in the intensive care unit following the acute onset of fever, influenza-like symptoms, meningism, facial palsy and nystagmus. Blood and cerebral spinal fluid samples were positive for LM on direct microscopic exam as well cultures. Treatment was initiated but the patient acutely deteriorated, exhibiting tetra paresis, bilateral pontomedullary syndrome, impairment of vigilance, and experienced a cardiac arrest. She was successfully resuscitated and remained in the intensive care unit with gradual and slow recovery. After a lengthy hospital stay, she was eventually discharged from the hospital and resumed a normal life, with few neurological sequelae such as dysphagia and mild facial palsy. To investigate the patient's sleep complaints, an in-laboratory full polysomnography was obtained and revealed central sleep apnoeas and hypopnoeas (Apnoea–Hypopnoea index (AHI)=50 events/hour) with severe nocturnal hypoxaemia. Morning arterial blood gases revealed alveolar hypoventilation with partial pressure of arterial CO2 or PaCO2 of 6.7 kPa and PaO2 of 9.5 kPa. The patient refused further investigations and therapy but agreed to return to clinic for a follow-up in 1 year. In 1994, polysomnography and arterial blood gases showed persistent sleep apnoea and daytime hypoventilation but the patient continued to decline treatment. The patient was then lost to follow-up until 2011, when she presented for the third time to the Sleep Clinic complaining of daytime fatigue, unrefreshing sleep, choking episode during sleep and …
Patterns of kidney injury in pediatric nonkidney solid organ transplant recipients

The incidence of acute kidney injury (AKI) and its impact on chronic kidney disease (CKD) following pediatric nonkidney solid organ transplantation is unknown. We aimed to determine the incidence of AKI and CKD and examine their relationship among children who received a heart, lung, liver, or multiorgan transplant at the Hospital for Sick Children between 2002 and 2011. AKI was assessed in the first year posttransplant. Among 303 children, perioperative AKI (within the first week) occurred in 67% of children, and AKI after the first week occurred in 36%, with the highest incidence among lung and multiorgan recipients. Twenty‐three children (8%) developed CKD after a median follow‐up of 3.4 years. Less than 5 children developed end‐stage renal disease, all within 65 days posttransplant. Those with 1 AKI episode by 3 months posttransplant had significantly greater risk for developing CKD after adjusting for age, sex, and estimated glomerular filtration rate at transplant (hazard ratio: 2.77, 95% confidence interval, 1.13‐6.80, P trend = .008). AKI is common in the first year posttransplant and associated with significantly greater risk of developing CKD. Close monitoring for kidney disease may allow for earlier implementation of kidney‐sparing strategies to decrease risk for progression to CKD.
Decision-Making Training Reduces the Attentional Blink

Practice or training on a particular task often yields gains for the trained task; however, the extent to which these benefits generalize to other stimuli/tasks is contentious. It has been suggested that behavioral decision-making/response selection training may enhance temporal visual attention, as measured using the attentional blink (AB) paradigm. Here, we show that AB can indeed be reduced through response selection training, which requires repeatedly performing a speeded decision-making task. Training gains garnered by this approach transferred to distinct AB measures, but not to unrelated measures of visual search and multitasking ability. Moreover, these changes were still evident 2 weeks after training completion. Crucially, training on 2 active control tasks—visual search and motion discrimination—did not elicit similar gains. Such malleability of temporal visual attention via response selection training offers tantalizing prospects for future cognitive enhancement endeavors.
Antiviral activity of cationic amphiphilic drugs

ABSTRACT Introduction: Emerging and reemerging viral infections represent a major concern for human and veterinary public health and there is an urgent need for the development of broad-spectrum antivirals. Areas covered: A recent strategy in antiviral research is based on the identification of molecules targeting host functions required for infection of multiple viruses. A number of FDA-approved drugs used to treat several human diseases are cationic amphiphilic drugs (CADs) that have the ability to accumulate inside cells affecting several structures/functions hijacked by viruses during infection. In this review we summarized the CADs’ chemical properties and effects on the cells and reported the main FDA-approved CADs that have been identified so far as potential antivirals in drug repurposing studies. Expert commentary: Although there have been concerns regarding the efficacy and the possible side effects of the off-label use of CADs as antivirals, they seem to represent a promising starting point for the development of broad-spectrum antiviral strategies. Further knowledge about their mechanism of action is required to improve their antiviral activity and to reduce the risk of side effects.
Abnormal Substrate Levels That Depend upon Mitochondrial Function in Cerebrospinal Fluid from Alzheimer Patients

Background: Impaired oxidative and energy metabolism are important features in Alzheimer’s disease. These metabolic abnormalities may induce functional disturbances and are associated with significant cognitive impairment. Objective: To determine whether mitochondrial function is altered by Alzheimer’s disease, a quantitative analysis of substrates that enter the tricarboxylic acid cycle was carried out in cerebrospinal fluid (CSF) from Alzheimer patients. Methods: Organic acid levels related to carbohydrate oxidation were measured in CSF from patients affected by dementia of Alzheimer type (n = 17) and from nondemented elderly controls (n = 17) using a gas chromatography/mass spectrometry system. CSF glucose and glutamine concentrations were determined by a quantitative enzymatic method and by ion exchange chromatography, respectively. Results: Compared to age-matched controls, patients had a higher CSF level of lactate (p = 0.002) and a lower mean level of succinate (p = 0.002), fumarate (p = 0.003) and glutamine (p = 0.0005). The CSF glucose level was not modified. Conclusion: Our results suggest an impairment of mitochondrial oxidative metabolism in brain cells of patients with Alzheimer’s disease.
Social Learning versus Traditional Teaching in an Elementary School Cardiovascular Health Promotion Program

Coronary heart disease in adults can be traced to lifestyle behaviors such as obesity and a diet high in fat, cholesterol, and calories. Children with poor health habits are likely to be at greatest risk for adult heart disease, because behavioral and physiologic risk factors are carried into adulthood? One strategy for preventing cardiac problems is school-based nutrition education, which can be guided by a variety of theoretical models of education. A traditional teaching strategy emphasizes knowledge acquisition. The assumption is that changing knowledge about food can change eating behavior and attitudes. However, knowledge alone is often inadequate to modify children’s eating habits, z Alternatively, social learning theory~’4 explains how individuals acquire and maintain behaviors in their environment. The teaching approach emphasizes skill building, role modeling, and goal setting to change behavior, rather than relying on knowledge acquisition. The purpose of this study was to compare a program of nutrition education guided by social learning theory with a more traditional teaching approach. It was hypothesized that students receiving the social learning approach would realize greater improvements in cognitive and behavioral responses, leading to favorable physiologic changes.
Driving force of the orbital-relevant electronic nematicity in Fe-based superconductors

The electronic nematic responses in Fe-based superconductors have been observed ubiquitously in various experimental probes. One novel nematic character is the d-wave bond orbital-relevant nematic charge order which was firstly proposed by symmetry analysis and then conformed by angle-resolved photoemission spectroscopy. In this paper, we present a mechanism that the driving force of the orbital-relevant nematic charge order is the reduction of the large Hubbard energy in the particle-hole charge channel by virtual hopping processes. This is one scenario from strong-coupling consideration. The same virtual hopping processes can lead to a super-exchange interaction for the spin magnetic order in the particle-hole spin channel and a pairing interaction for the superconducting order in the particle-particle channel. Thus the electronic nematic order, the spin magnetic order and the pairing superconducting order are intrinsically entangled and they can all stem from the same microscopic virtual hopping processes in reduction of the Hubbard energy. The electronic nematicity, the spin magnetism and the pairing superconductivity in unconventional superconductors are proposed to be unified within this mechanism.
A simple way of image encryption using pixel shuffling and pixel manipulation

Encryption is an important matter for which secured transmitting is taking place in every aspect of life. Validity and security can't be imagined in any aspect of communication without it. There are several methods for encrypting images like as chaos based encryption, stenography, watermarking etc. Chaotic encryption is comparatively popular schemes and many studies have covered this sector. But upgrade is still possible because of transmission properties, control parameter, computational complexity, industrial aspects, and so on. This study has shown an easy way to perform a complex encryption using simple logistic map. Variable parameter, robustness and easy to implement are core outcome of this study. All of this has done in two core steps where first step is for manipulating the pixel value and second step is for pixel position shuffling. For adding more strength 128 bit encryption scheme has been included.
A new compound, methylbergenin along with eight known compounds with cytotoxicity and anti-inflammatory activity from Ardisia japonica

Abstract A new compound, methylbergenin (1), was isolated from the whole plants of Ardisia japonica (Thunb.) Bl. (Myrsinaceae), along with eight known compounds: demethoxybergenin (2), bergenin (3), afzelin (4), quercitrin (5), bauerenol (6), bauerenone (7), α-spinasterol (8) and chondrillasterone (9). Compounds 1, 7 and 9 were isolated from A. japonica for the first time. The structure of compound 1 was determined on the basis of NMR (1D and 2D) and mass spectroscopic analysis. The absolute configuration of 1 was assessed by single-crystal X-ray diffraction. Compounds 1, 4, 5, 7 and 9 showed potential inhibitory effects against nitric oxide production in LPS stimulated RAW 264.7 murine macrophages. In addition, Compounds 7 and 9 exhibited cytotoxicity against A549 and HepG-2 cells.
Efficient Flow Instantiation via Source Routing in Software Defined Vehicular Networks

Software Defined Vehicular Networks (SDVN) brings a set of attractive features to vehicular networks along with an upgrade in the performance. Yet, SDVN suffers from frequently compelling to contact the centralized control plane, which in turn generates a high latency and packet overhead in the communication. The current solution to reduce the delay, proactive approach, does not bring the packet overhead down and impose a lot of stress on the controller with a decline of Packet Delivery Ratio (PDR). As an alternative, we introduce a source routing based flow instantiation operation with intelligent route caching that reduces the extent of communication with the control plane, but still manages to utilize the knowledge of controller while maintaining a lower latency and packet overhead.
Automatic 2-D/3-D Vessel Enhancement in Multiple Modality Images Using a Weighted Symmetry Filter

Automated detection of vascular structures is of great importance in understanding the mechanism, diagnosis, and treatment of many vascular pathologies. However, automatic vascular detection continues to be an open issue because of difficulties posed by multiple factors, such as poor contrast, inhomogeneous backgrounds, anatomical variations, and the presence of noise during image acquisition. In this paper, we propose a novel 2-D/3-D symmetry filter to tackle these challenging issues for enhancing vessels from different imaging modalities. The proposed filter not only considers local phase features by using a quadrature filter to distinguish between lines and edges, but also uses the weighted geometric mean of the blurred and shifted responses of the quadrature filter, which allows more tolerance of vessels with irregular appearance. As a result, this filter shows a strong response to the vascular features under typical imaging conditions. Results based on eight publicly available datasets (six 2-D data sets, one 3-D data set, and one 3-D synthetic data set) demonstrate its superior performance to other state-of-the-art methods.
An investigation of scheduling algorithm and their metrics in cloud computing

Cloud computing delivers efficient and elastics mean of various services to the end users by large-scale data centers. The fundamental issue in Cloud computing is achieving user satisfaction and efficient resource utilization. Day by day, huge amount of resources are processing i.e., Cloud users continuously request for services or resources from the cloud, so proper resource allocation is important to satisfy user demands. In Resource allocation, the most important aspect is Scheduling. Scheduling improves resource utilization. In this paper, an extensive investigation is carried on with the existing scheduling algorithm. The result of the investigation is tabulated with their performance parameter metrics like response time, energy efficiency, throughput, and latency.
The generation and subtraction of sensory expectations within cerebellum-like structures.

The generation of expectations about sensory input and the subtraction of such expectations from actual input appear to be important features of sensory processing. This paper describes the generation of sensory expectations within cerebellum-like structures of four distinct groups of fishes: Mormyridae; Rajidae; Scorpaenidae; and Apteronotidae. These structures consist of a sheet-like array of principal cells. Apical dendrites of the principal cells extend out into a molecular layer where they are contacted by parallel fibers. The basilar regions of the arrays receive primary afferent input from octavolateral endorgans, i.e., electroreceptors, mechanical lateral line neuromasts, or eighth nerve endorgans. The parallel fibers in the molecular layer convey various types of information, including corollary discharge signals associated with motor commands, sensory information from other modalities such as proprioception, and descending input from higher stages of the sensory modality that is processed by the structure. Associations between the signals conveyed by the parallel fibers and particular patterns of sensory input to the basal layers lead to the generation of a negative image of expected sensory input within the principal cell array. Addition of this negative image to actual sensory input results in the subtraction of expected from actual input, allowing the unexpected or novel input to stand out more clearly. Intracellular recording indicates that the negative image is probably generated by means of anti-Hebbian synaptic plasticity at the parallel fiber to principal cell synapse. The results are remarkably similar in the different fishes and may generalize to cerebellum-like structures in other sensory systems and taxa.
Neural Representations of the Full Spatial Field in Auditory Cortex of Awake Marmoset (Callithrix jacchus)

&NA; Unlike visual signals, sound can reach the ears from any direction, and the ability to localize sounds from all directions is essential for survival in a natural environment. Previous studies have largely focused on the space in front of a subject that is also covered by vision and were often limited to measuring spatial tuning along the horizontal (azimuth) plane. As a result, we know relatively little about how the auditory cortex responds to sounds coming from spatial locations outside the frontal space where visual information is unavailable. By mapping single‐neuron responses to the full spatial field in awake marmoset (Callithrix jacchus), an arboreal animal for which spatial processing is vital in its natural habitat, we show that spatial receptive fields in several auditory areas cover all spatial locations. Several complementary measures of spatial tuning showed that neurons were tuned to both frontal space and rear space (outside the coverage of vision), as well as the space above and below the horizontal plane. Together, these findings provide valuable new insights into the representation of all spatial locations by primate auditory cortex.