Miracle-dz/UniFAR-FTUs huggingface dataset:
A Comparative Study On Neural Network Based Rule Extraction Algorithm And C 4 . 5

Classification is one of the data mining problems receiving great attention recently in the database community. This paper proposes a comparative study to highlight the significant difference between the C4.5 decision tree based algorithm and the neural network approach for classification and rule extraction. We compare the rules generated by the C4.5 with that generated by the RX (Neural Network based Algorithm). This is experimentally evaluated in different domains. The Experimental results demonstrate that rules extracted from neural networks are comparable with those of decision trees in terms of predictive accuracy, number of rules and average number of conditions for a rule. Key-Words: Data mining, classification, rule extraction, decision tree, neural network, machine learning.
Marine Protected Areas as Fishery Policy: A Discussion of the Potential Costs and Benefits

Marine protected areas (MPAs) are currently receiving considerable attention as a "new" tool to control overexploitation. Many advocates argue that MPAs will provide a plethora of benefits ranging from improved habitat to higher fish stocks with little costs. Fishermen argue, not surprisingly, that the costs resulting from closing areas could be significant and need to be considered in the debate. In this paper, a set of biological, industry, and management hypotheses drawn from the literature analyzing the effects of MPAs are discussed. In doing so, a framework is presented that can be used to assess the expected returns to society from investing in MPAs.
HandsFree-Next Generation Sequence Processing , Mapping and Analysis Made Easy

As the speed and throughput of next-generation sequencing improve there is a continuously increasing demand for speedy post-sequencing data analysis. HandsFree is a cloud-based service designed for nonBioinformaticians that allows users to upload, map and process sequenced RNA-seq, DNA-seq, and ChiP-seq data. The system offers the user a pre-built pipeline that addresses the early, procedural steps of the logical progression from data generation to knowledge generation. HandsFree alleviates the configuration overhead and the need of the identification and installation of analytical tools on a local or rented computing infrastructure while offering an intuitive user-interface that assumes little to no technical expertise and requires minimal input by the user. URL: http://cm.jefferson. edu/HandsFree
Regional issues on animal genetic resources: trends, policies and networking in Europe

Los paises europeos estan, tanto individualmente como en colaboracion, llevando a cabo un trabajo activo sobre los recursos zoogeneticos (AnGR por sus siglas en ingles). La region tiene un muy buen punto de partida para trabajar en los AnGR: el concepto de raza se desarrollo en Europa; las actuales razas europeas reconocidas descienden de las antiguas razas autoctonas y, en muchas especies, han formado la mayor parte del nucleo de las razas internacionales; ha existido siempre una investigacion activa en Europa sobre los recursos zoogeneticos y mejora genetica, incluida la utilizacion sostenible y la gestion de la variacion. Desde la decada de los setenta y los ochenta muchos paises europeos han prestado atencion a las razas autoctonas y han salvado a muchas de ellas de su total extincion. En bastantes paises el trabajo de conservacion se ha basado en la criopreservacion. En el proceso de coordinacion de la FAO, Europa ha contribuido activamente a la evaluacion de La situacion de los recursos zoogeneticos mundiales y seguira implementando el Plan de accion mundial. Actualmente existen Planes de accion nacionales en la mayor parte de los paises europeos. El consumo de productos de origen animal en Europa ha cambiado muy poco a lo largo de las ultimas decadas. Asimismo, la produccion se ha intensificado notablemente. El desarrollo de la agricultura esta regido principalmente por las politicas de la UE. En la ultima decada hemos sido testigos de una nueva corriente de pensamiento y de unas medidas orientadas hacia una consideracion mundial del desarrollo rural. Esto ha dado lugar a la revitalizacion de muchas razas autoctonas. El objetivo es contar con esquemas que promuevan el auto-sostenimiento economico de las razas autoctonas. La UE posee tambien un programa de investigacion muy ambicioso para apoyar estos objetivos al tiempo que mejora la produccion en general y la gestion sostenibles de los recursos biologicos. El Punto focal europeo para los recursos zoogeneticos (ERFP por sus siglas en ingles) es un foro comun para los coordinadores de los programas nacionales europeos sobre los AnGR. Tambien existen muchas organizaciones no gubernamentales que trabajan en pro del sector de los animales de produccion en general y de la conservacion de los AnGR y en la mejora animal en particular. Estas ONGs y las redes son esenciales para crear conciencia acerca de la importancia de los valores de los AnGR y ponen de relieve las actividades que contribuyen a conservar y utilizar de forma sostenible los AnGR.
Antriebsschaltung für ein Schienenfahrzeug

Es wird eine Antriebsschaltung fur ein Schienenfahrzeug mit mehreren, zwischen einem Fahrdraht/Stromabnehmer-System (1) und einem Rad/Schiene-System (2) uber mindestens eine Drossel (4) in Reihe geschalteten ersten Teilstromrichtersystemen (6.1.6.n) vorgeschlagen, wobei jedes erste Teilstromrichtersystem aus mindestens einem primarseitigen Vierquadrantensteller (7), einem primarseitigen Gleichspannungszwischenkreis (8), mindestens einem primarseitigen Wechselrichter (10), mindestens einem Transformator (12) und mindestens einem sekundarseitigen Vierquadrantensteller (14) besteht. Sekundarseitig bilden parallelgeschaltete zweite Teilstromrichtersysteme (17.1.17.m) einen gemeinsamen sekundarseitigen Gleichspannungszwischenkreis (15). Der sekundarseitige Gleichspannungszwischenkreis (15) ist mit einer Anlaufschaltung (23) verbunden, um das Aufstarten der Antriebsschaltung zu bewirken. Die Speisung der netzseitigen Leittechnik inklusive der Ansteuereinrichtungen fur die Halbleiterschalter erfolgt uber die jeweiligen primarseitigen Gleichspannungszwischenkreise (8) oder aus den Wechselspannungen der jeweiligen primarseitigen Wechselrichter (10) oder aus den primarseitigen Wechselspannungen der jeweiligen Transformatoren.
Enhancement of Ferromagnetic Ordering Curie Temperature in N-Doped MgO under Hydrostatic Pressure

We have explored the magnetic properties of Nitrogen doped cubic MgO using the full potential linearized augmented plane wave (FP-LAPW) method. The unit cell has 128 atoms, and two Nitrogen atoms are placed in the positions of oxygen sites. This corresponds to 3.125% doping concentration. Our calculations predict that the ferromagnetic state, with a magnetic moment of about 1.0 μB per Nitrogen-dopant, is more favorable in energy than the nonmagnetic state, and the ferromagnetic correlations are influenced by the impurity bound state. The magnetic moment mainly arises from p orbital of Nitrogen which substitutes the Oxygen atom, with a little contribution from the Oxygen atoms surrounding Nitrogen atom. The resulting band structure and densities of states agree well with the recent theoretical works. The ferromagnetic ordering temperatures obtained from DFT simulations have been given in detail. Our results show that the pressure enhances the temperature in MgO:N.
Renewable , CO 2 emissions , Trade Openness , and Economic growth in Iran

This study examines the potential of Renewable Energy Consumption (REC) in decreasing the impact of carbon emission in Iran and the Greenhouse Gas (GHG) emissions, which leads to global warming. Using the Environmental Kuznets Curve (EKC) hypothesis, this study analyses the impact of electricity generated using RES on the environment and trade openness for the period 1975-2011, using the Autoregressive Distributed Lag (ARDL) approach. Results of unit root tests show that all variables are non-stationary in their level form and stationary in first difference form. The Cointegration analysis shows that there is evidence of cointegration among the test variables. The validity of the Environmental Kuznets Curve (EKC) hypothesis has been tested for these countries. Granger causality tests represent the existence of a unidirectional causality running from the square of per capita output to per capita CO2 emissions and renewable energy. The renewable energy consumption and economic growth has a positive bidirectional causality and contribution on emissions in the short-term. There are certainly some clarifications that justify the causes of contribution of renewable energies on the emissions. Key-Words: Renewable Energy, CO2 emissions, Economic growth, Iran, Trade openness, ARDL.
Development of soft-core system for heart rate and oxygen saturation

This paper is about the development of non-invasive heart rate and oxygen saturation in human blood using Altera NIOS II soft-core processor system. In today's world, monitoring oxygen saturation and heart rate is very important in hospitals to keep track of low oxygen levels in blood. We have designed an Embedded System On Peripheral Chip (SOPC) reconfigurable system by interfacing two LED’s of different wavelengths (660 nm/940 nm) with a single photo-detector to measure the absorptions of hemoglobin species at different wavelengths. The implementation of the interface with Finger Probe and Liquid Crystal Display (LCD) was carried out using NIOS II soft-core system running on Altera NANO DE0 board having target as Cyclone IVE. This designed system is used to monitor oxygen saturation in blood and heart rate for different test subjects. The designed NIOS II processor based non-invasive heart rate and oxygen saturation was verified with another Operon Pulse oximeter for 50 measurements on 10 different subjects. It was found that the readings taken were very close to the Operon Pulse oximeter. Keywords—Heart rate, NIOS II, Oxygen Saturation, photoplethysmography, soft-core, SOPC.
Distance based Dynamical System Modulation for Reactive Collision Avoidance

An algorithm which allows the robot to avoid obstacles and to reach the assigned goal is proposed. For this purpose, a dynamical system (DS) modulation matrix is calculated using the distance from the obstacles, without the need of analytical representation of the obstacles. This matrix modulates a generic first order DS, used to generate the desired path. In this way we guarantee the obstacles avoidance and the reaching of the goal. The effectiveness of the proposed approach is validated with an experiment on a 7 DOF KUKA light weight arm.
Assessment of carbonate concentration and characterization of marine sediments by Fourier Transform Infrared Spectroscopy

Fourier Transform Infrared Spectroscopy (FTIR) is a well established method for the characterization of mineralogical and geochemical properties of marine sediments. Understanding the biogeochemical changes in marine ecosystems is challenging task since it requires adequate analytical techniques and efforts. Biogeochemical characteristics of twenty one marine sediment samples collected off Chennai coast, Bay of Bengal, India were analyzed using FTIR spectroscopy. The FTIR peaks at 1460 cm (stretching vibration) and 880 cm (bending vibration) were used for carbonate determination. To verify the FTIR results, the obtained carbonate data were compared with carbonate values obtained by chemical analyses. The ranges of carbonate in sediments using FTIR and chemical analyses were 4.5–9.6% and 4.8–10%, respectively. The significant positive relationship was obtained between the carbonate results of FTIR and chemical analyses. This study demonstrates that instead of expensive and time consuming chemical methods, FTIR spectroscopic technique is found as a suitable, rapid and effective method for the quantification of carbonate in marine sediments.
Gas loading of graphene-quartz surface acoustic wave devices

Graphene was transferred to the propagation path of quartz surface acoustic wave devices and the attenuation due to gas loading of air and argon measured at 70 MHz and 210 MHz and compared to devices with no graphene. Under argon loading, there was no significant difference between the graphene and non-graphene device and the values of measured attenuation agree well with those calculated theoretically. Under air loading, at 210 MHz, there was a significant difference between the non-graphene and graphene devices, with the average value of attenuation obtained with the graphene devices being approximately twice that obtained from the bare quartz devices.
Coordination, ATB and ellipsis

"Shared constituents" such as what did in (3) are then to be handled in terms of ellipsis. In short, I advocate a return to the "large-conjunct-plus-reduction" conception of coordinations associated with early generative grammar (Chomsky 1957) although with reduction understood as "ellipsis" of terminals (PF-material) and not as deletion of syntactic structure. If (1/2) is replaced by (5b.), conjunctions uniting clauses can be seen as "discourse connectives", heads that take root clauses as their arguments. This conception fits most naturally with the idea mat coordinate structures should not be treated as symmetrical, n-ary branching, and multi-headed exceptions to XMheory (in particular, to the binary branching hypothesis of Kayne (1984), and the antisymmetry hypothesis of Kayne (1993)). However, it may be necessary to allow for "embedded" coordination I n coordination seems a pretty clear case, motivated on syntactic grounds. But I see no reason for assuming conjuncts can be any smaller than complete "extended projections" in the sense of Grimshaw (1991). If correct men the rationale for assuming ATB-rule application disappears. Further argumentation builds on the following points:
Analysis of Query Optimization Technique over Web Services

The query optimizer is the component of a database management system that attempts to determine the most efficient way to execute a query. The high quality, structured data from Web structured sources is invaluable for many applications. A critical but still largely unresolved question is: how to efficiently acquire the structured information inside Web databases through iteratively issuing meaningful queries? So, a general purpose Web Service Management System (WSMS) that enables querying multiple web services in a transparent and integrated fashion is analyzed. This paper tackles a first basic WSMS problem: query optimization for Select-ProjectJoin queries spanning multiple web services. Our main result is an algorithm for arranging a query’s web service calls into a pipelined execution plan that optimally exploits parallelism among web services to minimize the query’s total running time. Surprisingly, the optimal plan can be found in polynomial time even in the presence of arbitrary precedence constraints among web services, in contrast to traditional query optimization where the analogous problem is NP-hard.
KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR

The critical T790M mutation in EGFR, which mediates resistance to first- and second-generation EGFR tyrosine kinase inhibitors (TKI; gefitinib, erlotinib, and afatinib), has facilitated the development of third-generation mutation-selective EGFR TKIs (rociletinib and osimertinib). We previously reported heterogeneous afatinib-resistant mechanisms, including emergence of T790M-EGFR, and responses to third-generation EGFR TKIs. Here, we used afatinib-resistant lung adenocarcinoma cells [AfaR (formerly AFR3) cells], carrying exon 19 deletion/T790M in EGFR. To identify the novel resistance mechanisms in post-afatinib treatment, RocR1/RocR2 and OsiR1/OsiR2 cells were established using increasing concentrations of rociletinib and osimertinib, respectively. Attenuation of exon 19 deletion and T790M was confirmed in both rociletinib-resistant cells; in addition, EGFR and KRAS amplification was observed in RocR1 and RocR2, respectively. Significant KRAS amplification was observed in the osimertinib-resistant cell lines, indicating a linear and reversible increase with increased osimertinib concentrations in OsiR1 and OsiR2 cells. OsiR1 cells maintained osimertinib resistance with KRAS amplification after osimertinib withdrawal for 2 months. OsiR2 cells exhibited KRAS attenuation, and osimertinib sensitivity was entirely recovered. Phospho-EGFR (Y1068) and growth factor receptor–bound protein 2 (GRB2)/son of sevenless homolog 1 (SOS1) complex was found to mediate osimertinib resistance in OsiR1 cells with sustained KRAS activation. After 2 months of osimertinib withdrawal, this complex was dissociated, and the EGFR signal, but not the GRB2/SOS1 signal, was activated. Concomitant inhibition of MAPK kinase and EGFR could overcome osimertinib resistance. Thus, we identified a heterogeneous acquired resistance mechanism for third-generation EGFR TKIs, providing insights into the development of novel treatment strategies.
The Safety of an Adjuvanted Autologous Cancer Vaccine Platform in Canine Cancer Patients

Canine cancer rates are similar to humans, though the therapeutic options might be limited. Inducing a patient’s own immune system to have an anti-tumor response is an attractive approach to cancer therapy. In this safety study, autologous tumor vaccines produced specifically for each canine patient were combined with Advax™, a novel non-inflammatory immunomodulator and vaccine adjuvant and were tested for safety in a diverse range of patient presentations alone or in combination with other treatments. Canine patients had their tumor biopsied, debulked or resected and the tumor antigens were processed into an autologous vaccine formulated with Advax™ adjuvant with or without rhizavidin as an additional immune stimulant. Patients treated early in the trial received two intramuscular (IM) doses, 2 weeks apart. As the study progressed and no issues of safety were observed, the protocol was changed to weekly vaccinations for 4 weeks followed by monthly booster shots. Over the 150 I.M injections delivered to date, the vaccine was found to be very safe and no significant adverse reactions were observed. These results justify ongoing development and future controlled studies of this autologous vaccine approach.
The conditioning of linear boundary value problems

Investigation is made into the sensitivity of solutions of linear boundary value problems to perturbations of the boundary condition. We derive a useful quantity to decide for well or ill conditioning. From this it is deduced which kind of requirements the boundary conditions should meet in order to have a well conditioned problem. It is shown that this quantity can fruitfully be used to explain why, e.g., the multiple shooting technique is stable (in contrast to the single shooting one) for certain well posed problems having solutions with different growth behavior. The results are sustained by a number of examples.
A NEW APPROACH TO MODELING OF NOISE PARAMETERS OF FET ' S AND MODFET ' S AND THEIR FREQUENCY AND TEMPERATURE DEPENDENCE

A simple noise model of microwave MESFET (MODFET, HEMT, etc.) is described and verified at room and cryogenic temperatures. Closed form expressions for Tmin minimum noise temperature, Zgopt optimum generator impedance, gn noise conductance, and Z gopt generator impedance minimizing noise measure, are given in terms of frequency, the elements of FET equivalent circuits, and equivalent temperatures of intrinsic gate resistance and drain conductance to be determined from noise measurement. These equivalent temperatures are demonstrated in the example of Fujitsu FHRO1FH MODFET to be independent of frequency in the frequency range in which l/f noise is negligible. Thus, the model allows prediction of noise parameters for a broad frequency range from a single frequency noise measurement. The model predicts the noise behavior in general agreement with previous studies, but it is much simpler and all its parameters possess physical meanings. It also reconciles the existing discrepancies between different approaches to the modeling of noise properties of FET's.
WARM UP STATIC STRETCH VERSUS WARM UP DYNAMIC STRETCH ON SPRINT PERFORMANCE IN FOOTBALL PLAYERS

Background: Sprinting is the act of running over a short distance at (or near) top speed. It is used in many sports that incorporate running, typically as a way of quickly reaching a target or goal, or avoiding or catching an opponent. Objectives: The aim of this study was to investigate the effects of static stretch versus dynamic stretch protocols on sprint performance in football players. Method: 45 male football players were randomly classified into 3 groups. First group was Active Static Stretch group (ASS) (n=15), second group was Passive Static Stretch group (PSS) (n=15) and third group was Active Dynamic Stretch group (ADS) (n=15). The three groups performed a standard 10-min. jogging warm-up, followed by two 20-m sprints. The 20-m sprints were repeated after subjects performed the two stretch protocols. Results: The ASS and PSS groups had a significant increase in sprint period (P<0.05), while the ADS group had a significant decrease in sprint period (p>0.05). Conclusions: It was concluded that dynamic stretching as part of a warm-up seems to increase short sprint performance, but static stretching (active & passive) as part of a warm-up may decrease sprint performance.
A single case experimental design study on improving social communication skills after traumatic brain injury using communication partner telehealth training

ABSTRACT Primary objective: To investigate use of telehealth to deliver social communication skills training (TBIconneCT) to people with severe traumatic brain injury (TBI) and their communication partners (CPs). Research design: Feasibility study involving single case experimental design with two participants. Methods and procedures: TBI Express is an established program for improving social interactions between people with TBI and their CPs. To improve access to the program, we developed a modified version called TBIconneCT that can be delivered via videoconferencing. Two participants with TBI and their CPs completed TBIconneCT training. Outcome measures included exchange structure analysis of conversation samples, blinded ratings of conversation samples and self-report measures. Main outcomes and results: The study indicated positive change on blinded ratings of conversation and self-reported measures for both participants. Exchange structure analysis conducted on session-by-session data did not demonstrate treatment effects due to variability during baseline. Conclusion: This study indicated potential for using telehealth to provide social communication skills training to people with TBI and their families. The study findings provide a foundation for a phase one clinical trial which will compare in-person with videoconferencing delivery of TBIconneCT.
Measuring grain rotation at the nanoscale

ABSTRACT In this paper, we introduced a method to measure grain rotation of nanomaterials under external stress using a high pressure diamond anvil cell and the Laue microdiffraction technique at a synchrotron facility. We used tungsten carbide marker crystals to investigate grain rotation activities of 3 and 500 nm nickel media. Our results show that the grain rotation of 3 and 500 nm nickel nanocrystals increase with pressure and finally rotation of 500 nm nickel tends to stop at a lower pressure/stress level than 3 nm nickel. 3 nm nickel nanocrystals show a higher rotation magnitude than 500 nm nickel nanocrystals. Our measurements show an effective method to study the grain rotation of nanomaterials especially in ultrafine nanocrystals.