Miracle-dz/UniFAR-FTUs huggingface dataset:
Professional drivers and working time: journey sP an, rest, and accidents

Shift work is a reality in many sectors of industrial societies. Unfortunately, it is associated with several problems. Within this context, we highlight fatigue caused by extended working hours and the resulting increase in the risk of accidents. This is also a reality on Brazilian roads, with increasingly alarming rates of accidents involving intercity drivers. A significant number of such accidents is related to sleepiness caused by disruptions in the circadian rhythm. The necessity to drive for many consecutive hours without a pause, extended working hours, and mainly driving in the early hours of the morning may affect the driver’s wakefulness state and performance. This may be due to a lack of synchrony with the temperature curve, as well as melatonin levels. To minimize the risk of accidents, work schedules should include regular pauses during the work journey. Moreover, such schedules should prevent professional drivers from working for more than 10 consecutive hours, as the risk of accidents increases significantly after the 8th hour at the wheel.
Myogenic satellite cells and its application in animals - a review.

Myogenic satellite cells have been isolated and identified by several recently elucidated molecular markers. Furthermore, knowledge about the precise function of these markers has provided insight into the early and terminal events of satellite cells during proliferation, differentiation, transdifferentiation, specification and activation. Recently, quiescent myogenic satellite cells have been associated with possession of Pax 3 and 7 that represent pluripotent stem cells capable of differentiating into other lineages. However, the mechanism by which myogenic satellite cells attain pluripotent potential remain elusive. Later, transdifferentiating ability of these cells to another lineage in the absence or presence of certain growth factor/ or agents has revolutionized the scope of these pluripotent myogenic satellite cells for manipulation of animal production (in terms of quality and quantity of muscle protein) and health (in terms of repair of skeletal muscle, cartilage or bone).
A WIRELESS SENSOR NETWORK FOR POLYHOUSE CULTIVATION USING ZIGBEE TECHNOLOGY

The required climatic conditions for the polyhouse cultivation can be provided by using this proposed technique. The Zigbee technology has used for implementing the proposed wireless network. Few of the surrounding parameters of ambient temperature, humidity percentage, light intensity range and soil moisture content inside polyhouse are controlled and optimum conditions for crop growth inside polyhouse can be provided with the proposed model using abrupt actuators used. This model has developed with the mesh topology consists various nodes which are deployed inside polyhouse and are controlled by one central monitoring unit (CMU). Based on the crop the threshold values for the sensors and control values for the actuators during day time and night time are programmed in the CMU and it continuously receives the sensors data from all the nodes, and with respect to the programmed values of crop the CMU sends the controlling data to the actuator node for maintaining constant and required environmental conditions. By using this proposed model the necessity of human effort can be reduced and also the suitable weather conditions for the crop production irrespective of the season can be provided for the maximum beneficiary to the farmer.
Deliberation in negotiations

The past decade witnessed a growing interest in theories of deliberation and their application at the international level. This article takes stock of the state of the art. It argues that the ‘deliberative turn’ has forced both rationalist and constructivist scholars to refine their arguments and reconsider their methodology. We argue that the new research frontier for constructivists is in assessing under which circumstances arguments affect negotiating actors' preferences and subsequently lead to outcomes that are not easily explained in pure bargaining terms.
Rationale for Study of the Deep Subfascial Lymphatic Vessels During Lymphoscintigraphy for the Diagnosis of Peripheral Lymphedema

Purpose The current study aimed to determine the utility of including the study of deep subfascial lymphatic vessels in a 2-compartment lymphoscintigraphy for the diagnosis of lymphedema in patients with limb swelling. Lymphoscintigraphy is a valuable imaging tool for the timely diagnosis of peripheral lymphedema. However, there is a lack of standardization in its application, especially regarding which type of lymphatic vessels to examine (superficial, deep, or both). Methods Two hundred fifty-eight patients with lymphedema underwent segmental lymphoscintigraphy. The transport index (TI) was calculated to categorize the flow of the superficial and deep vessels as normal (<10) or pathological (≥10). The scores from 248 patients (48 unilateral arm, 86 unilateral leg, 114 bilateral leg) were tested with a 3-way analysis of variance to examine the relationship between affected limb, deep or superficial pathways, and primary or secondary lymphedema. The relationship between clinical presentation and TI was also investigated. Results In general, primary and secondary lymphedema patients had similar patterns of lymphoscintigraphic lymphatic abnormalities. Patients with unilateral clinical presentation can have bilateral TI abnormalities. The vast majority of patients (88%–98%) had either the deep subfascial vessels alone, or both the superficial and deep vessels, with a pathological TI. Conclusions A 2-compartment lymphoscintigraphy is able to accurately detect lymphatic flow abnormalities in patients with limb swelling. Given that the vast majority of patients had deep lymphatic vessels abnormalities, inclusion of these vessels in the lymphoscintigraphic diagnostic protocol is recommended.
Role of Cation and Anions (K + , Cr 2 O 7 2- and P 2 O 7 4- ) Towards ion Association and Solvation in Aqueous and Aqueous d-Mannitol Mixtures at Different Temperatures

The conductance of potassium dichromate and pyrophosphate has been measured in the concentration range of 1×10 -3 to 6×10 -2 composition dependence of Walden product, the influence of the d-mannitol mixtures on the solvation of ions has been discussed. The values of the association constants, KA, are used to obtain various thermodynamic parameters for the association process in the solution. It has been observed that the electronic contribution is totally negligible towards the standard transfer thermodynamic quantities.
A novel H‐shaped patch antenna

A novel H‐shaped patch antenna suitable for wireless and satellite communications is presented. The new antenna has some advantages compared to conventional microstrip patch antennas, such as small size, a fewer number of modes, no harmonic resonance, and the provision of pure reactive impedances at its harmonics that can result in increasing the transmitter efficiency. The basic principles and design procedure are introduced. Two antennas at two different frequencies, 4 and 10 GHz, are designed, fabricated, and measured. The measured results show a good agreement with the predicted ones. © 2001 John Wiley & Sons, Inc. Microwave Opt Technol Lett 29: 62–66, 2001.
Cost Variations in a Differentiated Good Oligopoly

In the homogenous good case, the relationship between market struc- ture and efficiency was studied extensively. Assuming a standard quadratic utility with quantity competition, this paper carries on the analysis in a differentiated good context. It can be shown that there is a positive re- lationship between market heterogeneity and efficiency, too. In contrast to the homogenous good case, consumer surplus as well as producer surplus increases with the dispersion of marginal costs.
Improved Adaptive Sliding Mode Control for a Class of Uncertain Nonlinear Systems Subjected to Input Nonlinearity via Fuzzy Neural Networks

The paper presents an improved adaptive sliding mode control method based on fuzzy neural networks for a class of nonlinear systems subjected to input nonlinearity with unknown model dynamics. The control scheme consists of the modified adaptive and the compensation controllers. The modified adaptive controller online approximates the unknown model dynamics and input nonlinearity and then constructs the sliding mode control law, while the compensation controller takes into account the approximation errors and keeps the system robust. Based on Lyapunov stability theorem, the proposed method can guarantee the asymptotic convergence to zero of the tracking error and provide the robust stability for the closed-loop system. In addition, due to the modification in controller design, the singularity problem that usually appears in indirect adaptive control techniques based on fuzzy/neural approximations is completely eliminated. Finally, the simulation results performed on an inverted pendulum system demonstrate the advanced functions and feasibility of the proposed adaptive control approach.
Antidiarrheal and antioxidative capability of synbiotic yogurt to the rats

The objective of this research was to utilize the local probiotic lactic acid bacteria, isolated from beef in some traditional markets in Bogor (L. plantarum 2C12 and L. fermentum 2B4), in synbiotic yogurt making and analyzing its antidiarrheal and antioxidative capability in rat models. The rats were treated with synbiotic yogurt and enteropathogenic Escherichia coli (EPEC) intervention. The antidiarrheal parameters were the appearance and the gravimetrically water content of the rats’ feces. The normal feces was round or oval, black, and hard or soft with lower fecal water content. The diarrheal feces was not round nor oval, liquid or unformed, brownish, and soft or slimy with higher fecal water content. The antioxidative parameter was immunohistochemically superoxide dismutase (SOD) content in liver and kidney tissues, shown by brown color in nucleus. This synbiotic yogurt showed antibacterial and antidiarrheal activities in the rat’s model. This research shown that the feces of the rats, which were infected by EPEC and treated by synbiotic yogurt contained L. fermentum 2B4 was normal, specifically oval, black, and soft feces. Whereas, the rats which were infected by EPEC, but were not treated by the synbiotic yogurt shown the diarrheal feces. The synbiotic yogurt also had antioxidative effect. For 21 days treatment with synbiotic yogurt to the EPEC intervention rats, the Cu, ZnSOD content in the liver and kidney increased, 17.72 and 24.96% respectively higher than the rats that were not treated with it.
Influence of multi-microphone signal enhancement algorithms on auditory movement detection in acoustically complex situations

The influence of hearing aid (HA) signal processing on the perception of spatially dynamic sounds has not been systematically investigated so far. Previously, we observed that interfering sounds impaired the detectability of left-right source movements and reverberation that of near-far source movements for elderly hearing-impaired (EHI) listeners (Lundbeck et al., 2017). Here, we explored potential ways of improving these deficits with HAs. To that end, we carried out acoustic analyses to examine the impact of two beamforming algorithms and a binaural coherence-based noise reduction scheme on the cues underlying movement perception. While binaural cues remained mostly unchanged, there were greater monaural spectral changes and increases in signal-to-noise ratio and direct-to-reverberant sound ratio as a result of the applied processing. Based on these findings, we conducted a listening test with 20 EHI listeners. That is, we performed aided measurements of movement detectability in two acoustic scenarios. For both movement dimensions, we found that the applied processing could partly restore source movement detection in the presence of reverberation and interfering sounds.
Dose Finding Method in Joint Modeling of Efficacy and Safety Endpoints in Phase II Studies

Determination of appropriate dose(s) to advance into Phase III trials is one of the most challenging and important tasks during drug development. Selecting a dose too high may result in unacceptable safety problems, while a too low dose may lead to ineffective drugs. Proper estimation of dose-response profiles for relevant safety and efficacy endpoints allows the reliable evaluation of the risk-benefit profile of a drug at the end of Phase II, as well as the selection of appropriate doses to be brought into confirmatory Phase III trials. Thus how to select dose(s) in Phase II trials by combining information about the efficacy and safety in a joint model setting may play a key role in drug development programs and can serve as a gate-keeper for large confirmatory Phase III trials with greater chance of success. Dose finding methods through joint modeling of both efficacy and safety endpoints are studied in this paper. To be more specific, we extend the popular MCP-Mod dose finding method (Bretz et al., 2005), which considered only the efficacy endpoint, to the method that incorporates both efficacy and safety endpoints through joint modeling. Method of parameter estimation for the extended models, and methods of selection of dose(s) to be brought into confirmatory Phase III trials based on Phase II study data are discussed in the paper. The performances of the proposed methods are evaluated through simulations.
On a constrained minimization problem arising in hemodynamics

Experimental evidence collected over the years shows that blood exhibits nonNewtonian characteristics such as shear-thinning, viscoelasticity, yield stress and thixotropic behaviour. Under certain conditions these characteristics become relevant and must be taken into consideration when modelling blood flow. In this work we deal with incompressible generalized Newtonian fluids, that account for the non-constant viscosity of blood, and present a new numerical method to handle fluid-rigid body interaction problems. The work is motivated by the investigation of interaction problems occurring in the human cardiovascular system, where the rigid bodies may be blood particles, clots, valves or any structure that we may assume to move rigidly. This method is based on a variational formulation of the fully coupled problem in the whole fluid/solid domain, in which constraints are introduced to enforce the rigid motion of the body and the equilibria of forces and stresses at the interface. The main feature of the method consists in introducing a penalty parameter that relaxes the constraints and allows for the solution of an associated unconstrained problem. The convergence of the solution of the relaxed problem is established and some numerical simulations are performed using common benchmarks for this type of problems. 2000 Mathematics Subject Classification: Primary 65M60; Secondary 74F10, 76Z05.
Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome

Viral Link to Chronic Fatigue Chronic fatigue syndrome (CFS) is a complex and debilitating disorder that is often linked to immune system dysfunction but whose cause(s) remain mysterious. Lombardi et al. (p. 585, published online 8 October; see the Perspective by Coffin and Stoye) now present a tantalizing new lead. In blood samples from 101 patients with well-documented CFS, over two-thirds (68) contained DNA from a recently described human gammaretrovirus, xenotropic murine leukemia virus–related virus (XMRV), which possesses sequence similarity to a murine leukemia virus. Cell culture assays confirmed that XMRV derived from CFS patient plasma and from T and B lymphocytes was infectious. Although the correlation with CFS is striking, whether the virus plays a causal role in the disorder remains to be determined. Interestingly, nearly 4% of the 218 healthy donors tested were positive for XMRV, which suggests that this virus—whose pathogenic potential is unknown—may be present in a significant proportion of the general population. Two-thirds of a sample of 101 U.S. patients with chronic fatigue syndrome harbor an infectious retrovirus in their blood cells. Chronic fatigue syndrome (CFS) is a debilitating disease of unknown etiology that is estimated to affect 17 million people worldwide. Studying peripheral blood mononuclear cells (PBMCs) from CFS patients, we identified DNA from a human gammaretrovirus, xenotropic murine leukemia virus–related virus (XMRV), in 68 of 101 patients (67%) as compared to 8 of 218 (3.7%) healthy controls. Cell culture experiments revealed that patient-derived XMRV is infectious and that both cell-associated and cell-free transmission of the virus are possible. Secondary viral infections were established in uninfected primary lymphocytes and indicator cell lines after their exposure to activated PBMCs, B cells, T cells, or plasma derived from CFS patients. These findings raise the possibility that XMRV may be a contributing factor in the pathogenesis of CFS.
Preparation of activated carbon from date palm trunks for removal of eosin dye

Date palm trees are abundant and cheap natural resources in Saudi Arabia. In this study, an activated carbon was prepared from palm trunks by chemical processes. The chemical activation was performed by impregnation of the raw materials after grinding with H 3 PO 4 solution (63%), followed by placing of the sample solution on a muffle furnace at 400 oC for 30 min, and then at 800 oC for 10 min. The morphology of the fabricated material was checked using scanning electron microscopy that showed the rough surfaces on the carbon samples. The use of fabricated activated carbon for removal of eosin dye from aqueous solutions at different contact time, initial dye concentration, pH and adsorbent doses was investigated. The experimental results show that the adsorption process attains equilibrium within 20 min. The adsorption isotherm equilibrium was studied by means of the Langmuir and Freundlich isotherms, and it was found that the data fit the Langmuir isotherm equation with maximum monolayer adsorption capacity of 126.58 mg g -1 . The results indicated that the home made activated carbon prepared from palm trunks has the ability to remove eosin dye from aqueous solution and it will be a promising adsorbent for the removal of harmful dyes from waste water.
A Comparative Study of Teachers’ Perceptions towards School’s Professional Development according to Their Demographics at No. 26 Basic Education High School in Mandalay, Myanmar

The main purpose of this study was to compare the significant differences in the teachers’ perceptions towards school’s professional development according to their demographics: age, grade level currently teaching and years of teaching experience at No. 26 Basic Education High School in Mandalay, Myanmar. The participants of this study were 96 teachers from No. 26 Basic Education High School at Mandalay, Myanmar during the academic year 2015-2016. This study was designed as quantitative and comparative study. Data was gathered using the research instrument, 5 Likert scaled questionnaire that consisted of two parts; Part I investigated the participants’ demographics and Part II compared the teachers’ perceptions. The data collected from the survey was analyzed by descriptive statistics; Frequency & Percentage, Mean, Standard Deviation and comparative analysis; One-Way Analysis of Variance (ANOVA). The transformed data of this study showed that teachers from No. 26 Basic Education High School, Mandalay had “positive” perceptions towards their school’s development activities. However, the comparative analysis described that there were no significant differences in the teachers’ perceptions towards school’s professional development according to their demographics: age, and grade level currently teaching and years of teaching experience at No. 26 Basic Education High School in Mandalay, Myanmar. Though the findings revealed no significant differences, it gave some ideas to create a professional development encompassing teachers’ multiple viewpoints in order to professionally organized learning environment where teachers’ wants, needs meet and it will make the students learn successfully.
OPTIMAL DESIGN FOR HIGH-TEMPERATURE BROADBAND RADOME WALL WITH SYMMETRICAL GRADED POROUS STRUCTURE

This study focuses on electromagnetic and thermo- mechanical optimal design for high-temperature broadband radome wall with symmetrical graded porous structure. The position- dependent porosity increases from the two surfaces of the structure to its intermediate layer. Electromagnetic and thermo-mechanical properties of the proposed structure are investigated simultaneously via numerical simulations. Optimal results suggest that the symmetrical porous structure possesses better broadband transmission performance in the 1{100GHz frequency range, in contrast to a traditional A-sandwich structure. The thermo-mechanical investigation also indicates that the novel structure meets the requirement for high- temperature (up to 1400 - C) applications.
Biosensors in Endocrinology- Review Article

Biosensors are classes of sensors in which at least a biological process is used in sensing procedure. They are generally composed of three parts: a sensing element, a transducer, and a signal processor (or detector). They can be categorized by type of sensing materials or by detection techniques. From their invention time up to now, various biological species have been analyzed using variety of biosensors. They have been widely used for environmental, industrial, pharmaceutical and clinical applications in many research papers. Perhaps the number of biosensors which had a chance to commercialize and enter to the market is limited, but by recent developments in science and technology, day-by-day, the number of commercial biosensors are growing. Their importance in clinical medicine can be found in determination of biomarkers for early diagnosis of disease or for control and manage of them in point-of-care devices. Diagnosis and control of many endocrine diseases and metabolic disorders depend strongly on determination of chemicals, hormones and antibodies. A large number of biosensors research studies have focused on determination of these biomolecules. One of the famous commercial biosensor is widely used in management of diabetes is glucometer. They are portable commercial biosensors which measure the amount of glucose in a blood drop. The main challenges in designing biosensors are decrease the limit of detection, increasing the sensitivity and accuracy in an analysis, increasing lifetime and miniaturization. Even scientists are now trying to develop biosensors for non-invasive measurements of biomarkers in saliva or tears.