Miracle-dz/UniFAR-FTUs huggingface dataset:
Carotenoids in Eggs and Plasma of Red‐Legged Partridges: Effects of Diet and Reproductive Output

Carotenoids are important dietary constituents in birds. They serve as pigments and play numerous physiological roles in both the laying hen and developing embryo. However, factors determining the absorption of carotenoids and their allocation to different functions are numerous and complex, and causal relationships are generally poorly known. Our objective was to determine the degree to which carotenoid levels in egg yolks and the plasma of hens were influenced by differences in diet and reproductive output in captive red‐legged partridges. Carotenoid concentrations were measured by high performance liquid chromatography in two feeds (high and low carotenoid content) and in yolks and plasma of hens near the start and end of laying. Early in the laying season, plasma and yolk carotenoids varied with diet and were correlated with one another. Late in the season, a dietary effect was evident only for yolks, and there was no relationship between plasma and egg levels of individual hens. However, plasma carotenoids at the end of laying were strongly correlated with the number of eggs that had been laid. Dietary availability, although important, could explain some variation in carotenoid levels in plasma and egg yolks only in the context of reproductive history.
Microcirculatory analysis in the management of sepsis-Occam's razor or Achilles' heel?*.

2628 www.ccmjournal. org December 2014 • Volume 42 • Number 12 3. Jackson JC, Pandharipande PP, Girard TD, et al; Bringing to light the Risk Factors And Incidence of Neuropsychological dysfunction in ICU survivors (BRAIN-ICU) study investigators: Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the BRAIN-ICU study: A longitudinal cohort study. Lancet Respir Med 2014; 2:369–379 4. Mikkelsen ME, Christie JD, Lanken PN, et al: The adult respiratory distress syndrome cognitive outcomes study: Long-term neuropsychological function in survivors of acute lung injury. Am J Respir Crit Care Med 2012; 185:1307–1315 5. Stevenson JE, Colantuoni E, Bienvenu OJ, et al: General anxiety symptoms after acute lung injury: Predictors and correlates. J Psychosom Res 2013; 75:287–293 6. Wunsch H, Christiansen CF, Johansen MB, et al: Psychiatric diagnoses and psychoactive medication use among nonsurgical critically ill patients receiving mechanical ventilation. JAMA 2014; 311:1133–1142 7. Bienvenu OJ, Gellar J, Althouse BM, et al: Post-traumatic stress disorder symptoms after acute lung injury: A 2-year prospective longitudinal study. Psychol Med 2013; 43:2657–2671 8. Sricharoenchai T, Parker AM, Raparia S, et al: A meta-analysis of posttraumatic stress disorder (PTSD) symptoms in intensive care unit survivors. Am J Resp Crit Care Med 2014; 189:A2534 9. Myhren H, Ekeberg Ø, Stokland O: Health-related quality of life and return to work after critical illness in general intensive care unit patients: A 1-year follow-up study. Crit Care Med 2010; 38:1554–1561 10. Sukantarat K, Greer S, Brett S, et al: Physical and psychological sequelae of critical illness. Br J Health Psychol 2007; 12:65–74 11. van der Schaaf M, Beelen A, Dongelmans DA, et al: Functional status after intensive care: A challenge for rehabilitation professionals to improve outcome. J Rehabil Med 2009; 41:360–366 12. Davydow DS, Hough CL, Zatzick D, et al: Psychiatric Symptoms and Acute Care Service Utilization Over the Course of the Year Following Medical-Surgical ICU Admission: A Longitudinal Investigation. Crit Care Med 2014; 42:2473–2481 13. Garrouste-Orgeas M, Coquet I, Périer A, et al: Impact of an intensive care unit diary on psychological distress in patients and relatives. Crit Care Med 2012; 40:2033–2040 14. Jones C, Bäckman C, Capuzzo M, et al; RACHEL group: Intensive care diaries reduce new onset post traumatic stress disorder following critical illness: A randomised, controlled trial. Crit Care 2010; 14:R168 15. Davydow DS, Zatzick D, Hough CL, et al: A longitudinal investigation of posttraumatic stress and depressive symptoms over the course of the year following medical-surgical intensive care unit admission. Gen Hosp Psychiatry 2013; 35:226–232
Extraction of pectin from citrus fruit peel and use as natural binder inparacetamol tablet

The aim of present study was to extract pectin from dried citrus fruit peels. In order to increase profits for citrus fruit growers and processors, citrus fruit peels, a by-product of citrus fruit processing, were investigated as a source of pectin. Pectin extraction was optimized from this by-product. Pectin was extracted under pH 2; Ethanol ratios(ER) 1:1 and extraction periods 120 min, at this condition highest yield was obtained 18.21%. Pectin assess its binding property in tablets using paracetamol as a model drug. Thereafter, four batches were formulated using pectin in different proportions. A reference batch of starch was also prepared to carry out the comparative study and to assess the binding property of pectin. Pre-compression and post-compression studies were performed for each formulation and compared to range as per pharmacopoeias. In vitro dissolution studies revealed that batch M3 showed 81.88% drug released. In-vitro release kinetic of all four batches followed korsmeyer-peppas models. Citrus peel pectin can act as excellent binder in dosage forms. Since it is of natural origin and citrus peels available at low cost it may prove to be better binder over commercially used synthetic binders.
Practical issues concerning imaging of pulmonary infection in children.

Pulmonary infection is the most common cause of illness in children and continues to be a significant cause of morbidity and mortality (1). Evaluation of suspected pneumonia is one of the most common indications for imaging in children. Because of the frequency at which this scenario arises, knowledge of the issues concerning the imaging of children with pneumonia is important. The roles of imaging in these children are multiple: confirmation or exclusion of pneumonia, characterization and prediction of infectious agent, exclusion of other cause of symptoms, evaluation when there is failure to resolve, and evaluation of acute and chronic complications. The timing and indications for imaging are different in otherwise healthy children and those who have underlying medical conditions such as immunodeficiency. A separate section at the end of this article pertains to immunocompromised children. The rest of the article pertains to otherwise healthy children with pneumonia.
La détection et la caractérisation de coronavirus et astrovirus chez les chiroptères au Cambodge et au Laos

Les zoonoses emergentes constituent un probleme de sante publique majeur. A l'image des virus de l'immunodeficience humaine (VIH), influenza, ou encore Ebola, la plupart des pathogenes zoonotiques prennent leur origine chez la faune sauvage. Les chiropteres sont des reservoirs de virus zoonotiques qui peuvent provoquer des pathologies graves chez l'Homme, comme le virus de la rage ou le coronavirus responsable de la pandemie du syndrome respiratoire aigu severe (SRAS) en 2003-2004. En Asie du Sud-Est, reconnue comme un point chaud d'emergence, les chiropteres sont regulierement en contact avec l'Homme du fait de l'exploitation des memes environnements et des activites de chasse et de consommation de ces animaux sauvages. Le risque de transmission de potentiels virus des chiropteres a l'Homme reste encore tres peu etudie, notamment au Cambodge et au Laos. C’est dans ce contexte que s’inscrit ce travail de these, qui a pour but de detecter et de caracteriser des coronavirus et des astrovirus chez les chiropteres de ces deux pays, et d'explorer les environnements ou le risque de transmission a l'Homme serait plus eleve.Un premier axe de travail a porte sur la detection et la caracterisation de ces deux familles virales chez des chiropteres echantillonnes de 2010 a 2013. Une forte diversite de coronavirus et d'astrovirus a ete detectee chez de nombreux genres de chiropteres insectivores et frugivores. De nouveaux hotes reservoirs et de nouvelles souches virales ont ete mis en evidence, dont certaines sont relativement proches de souches pathogenes chez l'Homme ou chez d'autres especes animales. Le deuxieme axe d'etude visait une caracterisation plus approfondie des virus. L'etude des proteines impliquees dans l'entree cellulaire (proteines de capside et de spicule pour les astrovirus et coronaivrus respectivement), permet d'evaluer le potentiel de passage de la barriere d'espece de ces virus. Plusieurs techniques de sequencage ont ete tentees, en particulier au niveau des genes d'interet. Les resultats ont ete tres limites, et n'ont pas permis une caracterisation approfondie des souches. Neanmoins, ce travail a mis en evidence les points critiques et les approches a envisager dans l'optique d'un futur sequencage de ces virus.Enfin, le troisieme axe de recherche a porte sur l'etude des facteurs environnementaux qui pourraient impacter les chiropteres et les potentiels virus zoonotiques qu'ils peuvent porter. Bien que les donnees aient ete limitees, l'approche methodologique et les pistes d'etude sont a retenir pour des etudes epidemiologiques futures. De plus les caracteristiques liees a la transformation des paysages naturels par l'Homme est un aspect important a prendre en compte.
Bifurcations caused by non-affinity of singularly perturbed control systems

The problem of stabilization for non affine in control systems with guaranteed transient performances is discussed. The fast dynamic output feedback controller with the highest output derivative in feedback loop is used, where the controller is proper and can be implemented without ideal differentiation. Two-time-scale motions are induced in the closed-loop system and the method of singular perturbations is used to analyze the closed-loop system properties. Stability conditions imposed on the fast and slow modes and sufficiently large mode separation rate can ensure the output stabilization at the origin of non affine system in such a way that the transient performances are desired and insensitive to external disturbances and variations of nonlinear system parameters. The effect of fast-motion subsystem bifurcations caused by non-affinity of the control system is emphasized and numerical examples with simulation results are presented.
Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble Flt-1.

OBJECTIVE The control of angiogenesis during chondrogenic differentiation is an important issue affecting the use of stem cells in cartilage repair, especially with regard to the persistence of regenerated cartilage. This study was undertaken to investigate the effect of vascular endothelial growth factor (VEGF) stimulation and the blocking of VEGF with its antagonist, soluble Flt-1 (sFlt-1), on the chondrogenesis of skeletal muscle-derived stem cells (MDSCs) in a rat model of osteoarthritis (OA). METHODS We investigated the effect of VEGF on cartilage repair in an immunodeficiency rat model of OA after intraarticular injection of murine MDSCs expressing bone morphogenetic protein 4 (BMP-4) in combination with MDSCs expressing VEGF or sFlt-1. RESULTS In vivo, a combination of sFlt-1- and BMP-4-transduced MDSCs demonstrated better repair without osteophyte formation macroscopically and histologically following OA induction, when compared with the other groups. Higher differentiation/proliferation and lower levels of chondrocyte apoptosis were also observed in sFlt-1- and BMP-4-transduced MDSCs compared with a combination of VEGF- and BMP-4-transduced MDSCs or with BMP-4-transduced MDSCs alone. In vitro experiments with mixed pellet coculture of MDSCs and OA chondrocytes revealed that BMP-4-transduced MDSCs produced the largest pellets, which had the highest gene expression of not only type II collagen and SOX9 but also type X collagen, suggesting formation of hypertrophic chondrocytes. CONCLUSION Our results demonstrate that MDSC-based therapy involving sFlt-1 and BMP-4 repairs articular cartilage in OA mainly by having a beneficial effect on chondrogenesis by the donor and host cells as well as by preventing angiogenesis, which eventually prevents cartilage resorption, resulting in persistent cartilage regeneration and repair.
Multiple urinary tract malformations with likely recessive inheritance in a large Somalian kindred.

Traditionally most non-cystic developmental disorders of the urinary tract have been regarded as sporadically occurring and morphologically distinct entities. However, familial occurrence of ureter-related abnormalities has pointed towards a genetic determination with a likely autosomal dominant mode of inheritance in a number of cases [1–5]. We report a Somalian kindred with seven out of 15 children affected by urinary tract malformations in a variety not reported yet. Furthermore, in sight of consanguineous healthy parents, this is the first report on a likely autosomal recessive mode of inheritance of urinary tract malformations.
Correlations of Perceived Flow, Perceived System Quality, Perceived Information Quality, and Perceived User Trust on Mobile Social Networking Service (SNS) Users' Loyalty

This research aims to examine the correlations of perceived flow, perceived system quality, perceived information quality and perceived user trust on mobile social networking service (SNS) usersâ€™ loyalty. Investigation of correlation between perceived user trust with perceived flow and user loyalty were also performed. Two hundred students were the subjects of a Malaysian university to answer survey questions on their currently chosen mobile social network system. The correlations between perceptual variables on mobile SNS were then analyzed and various causal relations deduced. Research findings indicate both perceived information quality and perceived system quality correlates with perceived flow and perceived usersâ€™ trust, which further correlate mobile SNS usersâ€™ loyalty. Perceived user trust correlates with perceived flow, and both factors correlates with user loyalty. Perceived flow is regarded as the strongest factor that correlates with usersâ€™ loyalty. The paper rounds off with conclusions and an agenda for future research in this area.
Myosin heavy chain fibre type composition in foals: analyses at the mRNA and protein level.

REASONS FOR PERFORMING STUDY An optimal developed musculoskeletal system is vital for the performance of the horse. Previously, we showed that in the m. gluteus medius from adult untrained horses, identical mRNA and protein expression patterns were found in the majority of fibres. However, co-expression of IIa and IId/x myosin heavy chain (MyHC) was substantially more common at the protein than at the mRNA level, suggesting a transcriptionally controlled fine-tuning of these 2 genes. OBJECTIVE To analyse the MyHC transcripts and proteins (including the cardiac alpha isoform) in the same muscle during post natal development when the muscle is adapting to movement and load. METHODS Biopsies were taken from the m. gluteus medius of 2 Dutch Warmblood foals at 0, 2, 4, 22 and 48 weeks of age. mRNA was compared to protein expression on a fibre-to-fibre basis using in situ hybridisation and immunofluorescence. The MyHC slow (I), alpha, IIa and IId/x isoforms were analysed. RESULTS At all ages the expression of the mRNA and protein MyHC isoforms was almost identical. Surprisingly, coexpression of the IIad isoform was also detected at the mRNA level especially early in life. The transcript of the alpha isoform was only detectable at young age, indicating silencing of the gene around birth. CONCLUSION During the first year of life, MyHCs are continuously adapting at the mRNA and protein level. Additionally, the regulation of hybrid fibres is different from that in adult fibres. POTENTIAL RELEVANCE We postulate that interfering in this process by e.g. early training will be levelled out by the maturation of the muscle.
Mexican-American ethnicity, socioeconomic status, and infant mortality: a county-level analysis.

The direct study of infant mortality among Mexican-Americans is constrained by lack of ethnic identification on the standard birth and death certificates; detailed and reliable data for analysis are not widely available. In this paper an indirect approach based on aggregate data is used to test hypotheses concerning the relationship between Mexican-American ethnicity and infant mortality. Specifically the percent of persons Spanish language/Spanish surname is correlated with overall infant neonatal and postneonatal mortality rates as well as late fetal death ratios for a sample of 168 counties in the southwestern United States. The results indicate that "counties with a greater proportion of Mexican-Americans experienced significantly higher rates of infant mortality. However when the socioeconomic characteristics of the county populations are controlled only the relationship between percent Mexican-American and fetal death ratios remains significant. Policy implications of the results are discussed in relation to previous literature concerning the infant mortality/socioeconomic status association. " (EXCERPT)
ANÁLISE DA IMPLANTAÇÃO E DA PÓS-IMPLANTAÇÃO DO SISTEMA DE GESTÃO AMBIENTAL DE UMA PEQUENA EMPRESA NO VALE DO RIO DOS SINOS

O objetivo desta pesquisa foi analisar a implantacao e a pos-implantacao de um Sistema de Gestao Ambiental em uma empresa de pequeno porte, localizadas na regiao do Vale do Rio dos Sinos, no Rio Grande do Sul. O estudo emprega tecnicas que abrange a pesquisa bibliografica, pesquisa de campo e o estudo de caso unico, sendo a coleta de dados atraves da entrevista semi-estruturada, da analise de dados documentais e da observacao direta na planta industrial. A entrevista foi realizada com o diretor da organizacao, sendo a entrevista reescrita em formato de narrativa, na forma de um texto coeso. A empresa implantou o sistema de gestao ambiental no ano de 2012, motivada pela adequacao a legislacao ambiental e ao mesmo tempo a antecipacao de novas leis ambientais. A principal dificuldade, apontada pelo empresario, para a implantacao do SGA foi a comunicacao entre os orgaos publicos contatados durante o processo. Alem do resultado positivo em relacao ao treinamento dos colaboradores, onde proporcionou atitudes proativas entre si, a empresa relatou uma significativa reducao de custos de agua e energia eletrica. O estudo oferece importantes contribuicoes acerca da implantacao da gestao ambiental nas organizacoes.
Non-asymptotic performance analysis of single-cycle detectors

In this paper, a new formulation of the probabilities of detection and false alarm for a class of cyclic-feature detectors known as single-cycle detectors is derived for additive white Gaussian noise channels. As opposed to previously published papers, the formulation derived here is non-asymptotic, being valid for any signal-to-noise ratio value. Additionally, the proposed formulation is general, allowing for the analysis of the single-cycle detection performance for any modulation scheme and any cycle frequency.
Closed head injuries in children following the use of a sarong cradle.

INTRODUCTION Sarong cradles are unique to South-East Asian culture. Their use can lead to injuries from falls, over-enthusiastic rocking and defective equipment. We present 19 children who attended the Accident and Emergency (A&E) Department of a general hospital and who sustained injuries while in a sarong cradle. All had closed head injuries. METHODS AND MATERIALS The data was collected over a 9-month period from September 1992 to May 1993. All patients with a documented history of fall following the use of a sarong cradle, were recruited into the study. The adults accompanying the patients were interviewed with a structured questionnaire. The information was recorded by the doctor in attendance. RESULTS The ages of the 19 patients ranged from 13 days to 29 months. There were 17 Chinese, 1 Malay and 1 Indian. The types of closed head injuries included minor head injury with no external signs of injury, scalp lacerations, scalp haematomas and severe head injury with an extradural haematoma. The majority (14) were discharged from the A&E Department with head injury advice, 4 were admitted to the General Neurosurgical ward and one, to the Neurosurgical Intensive Care Unit. There were no fatalities in this group. The accidents happened while the children were either sleeping (14), playing (4) or feeding (1). CONCLUSIONS While most head injuries sustained in this manner are usually mild, there is a potential that such injuries may lead to more serious injuries. Care givers who use the sarong cradle should be aware of the dangers and exercise due care during use.
Joint Power Control and Scheduling for Two-Cell Energy Efficient Broadcasting with Network Coding

We consider the energy minimization problem for a two-cell broadcasting system, where the focus is devising energy efficient joint power control and scheduling algorithms. To improve the retransmission efficiency, linear network coding is applied to broadcast packets. Combined with network coding, an optimal algorithm is proposed, which is based on dynamic programming. To reduce computational complexity, two sub-optimal algorithms are also proposed for large networks. Simulation results show that the proposed schemes can reduce energy consumption up to 57% compared with the traditional Automatic Repeat-reQuest (ARQ).
Path-Following Control of A Quadrotor UAV With A Cable-Suspended Payload Under Wind Disturbances

A path-following controller based on an uncertainty and disturbance estimator (UDE) for a quadrotor with a cable-suspended payload is proposed in this paper. The quadrotor and the payload are subject to unknown wind disturbances. The controller resembles a cascade architecture. For the outer loop, a UDE-based translational control law is proposed. The controller asymptotically stabilizes the quadrotor along a given path and estimates the lumped disturbances with a low-pass filter. For the inner loop, an attitude tracking controller is used to control the direction of the lift vector so that the actual lift force can asymptotically follow the reference force generated by the translational controller. The stability of the system with the translational controller and the attitude tracking controller has been shown to be asymptotically stable using the reduction theorem. With the help of the reduction theorem, the design of the translational and the attitude control can be decoupled, providing the flexibility of implementing different attitude controllers without redoing the stability analysis. As shown in the simulation, the control law can stabilize the quadrotor on the desired path under different wind disturbances.
Improving the Capabilities of Email for Businesses - the Case of Social Tagging

Email is one of the most used tools in enterprises for various purposes. However, the enterprise transformation programs are focusing today on social media tools rather than email. This paper discusses the properties of email in enterprises and whether further research is yet necessary on this tool. We provide a set of capabilities to compare between social media tools and email. As email is still affording some distinctive capabilities, we suggest improving this tool by applying a social bookmarking service to email messages. An experiment on the prototyped service highlights the perceived utility of email social tagging service for socializing employees' activities. The paper details, finally, future implications of this research.
Increased Susceptibility of β7-Integrin-Deficient Neonatal Mice in the Early Stage of Cryptosporidium parvum Infection

ABSTRACT Numerous inflammatory cells are recruited in response to Cryptosporidium parvum infection. These cells include interferon gamma-producing T lymphocytes, which are of major importance for the resolution of infection. Here, we show that β7 integrin is not essential for the control of infection in mice but that β7-deficient neonatal mice are more susceptible during the early stages of infection.