Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of plant growth regulators (BA, TDZ, 2-iP and NAA) on micropropagation of Aglaonema widuri

Aglaonema widuri is an evergreen and indoor ornamental plant. This study aimed to investigate the effect of some plant growth regulators on micropropagation of A. widuri. A protocol was developed for high frequency in vitro multiplication of A. widuri on the same medium for both shoots and roots induction. This condition decreases time duration and cost of micropropagation. Apical buds as explants were obtained from greenhouse-grown A. widuri and were established on Murashige and Skoog (MS) medium. Three cytokinins including N6-benzyladenine (BA; 0.00, 3.00, 3.50, and 4.00 mg l-1), 1-phenyl-3-(1,2,3-thiaiazol-5-yl), urea (TDZ; 0.00, 0.50, and 1.00 mg l-1), and N6-(2-isopentenyl) adenine (2-iP; 0.00 and 7.00 mg l-1), along with one auxin [α-naphtalene acetic acid (NAA; 0.00, 0.10, 0.20, 0.30, and 0.40 mg l-1) were studied for their effect on micropropagation of A. widuri. The plantlets were transferred to pots and grown in the greenhouse with a success rate of 95%. BA and NAA treatments as 3.00 mg l-1+ 0.2 mg l-1 recorded the highest shoot proliferation rate (number: 6.00 shoots and length: 7.75 cm per explant). Treatment of 4.00 mg l-1 BA + 0.10 mg l-1 NAA + 0.50 mg l-1 TDZ produced maximum nodes (13.25 per explant). The largest number of leaves (4.25 per explant) was produced in the medium containing 3.50 mg l-1 BA + 0.20 mg l-1 NAA. Maximum root initiation and development (14.25 per explant) was obtained on the medium containing 3.00 mg l-1 BA + 0.20 mg l-1 NAA. The combination of 3.50 mg l-1 BA + 0.20 mg l-1 NAA was found to be the most suitable growth regulator for obtaining the highest root length (8.25 cm per explant).
Cardiotoxicidad por trastuzumab en pacientes con cáncer de mama. Serie de casos

Resumen Antecedentes: la disfunción ventricular por trastuzumab (DV-TTZ) es una manifestación de cardiotoxicidad con injuria habitualmente reversible, transitoria y dosis independiente. Su detección precoz mediante ecocardiograma transtorácico (ETT) permite la modificación de esquemas terapéuticos y el inicio de fármacos cardioprotectores. Objetivo: evaluar la presencia de cardiotoxicidad por TTZ manifestada como disfunción del ventrículo izquierdo (VI) en el ETT y su evolución frente a la suspensión de TTZ e inicio de fármacos cardioprotectores. Material y métodos: estudio observacional; serie de casos. Se seleccionaron retrospectivamente pacientes que iniciaron tratamiento con TTZ por cáncer de mama con al menos cinco ETT consecutivos y que cumplieran criterios de DV-TTZ definida como la reducción relativa de la fracción de eyección del ventrículo izquierdo (FEVI) >10% respecto a la basal, con FEVI final <53%. Se registraron: edad, estadio de la enfermedad, factores de riesgo cardiovascular, número de ciclos de TTZ, tiempo de exposición, FEVI, porcentaje de reducción y tiempo a la normalización de la misma. Se calculó FEVI mediante método de Simpson. Las variables numéricas se expresan como mediana y rango. Resultados: de un total de 43 pacientes con riesgo de DV-TTZ, durante el período 2014-2017, se muestran resultados de los ocho casos que cumplieron criterios de inclusión. Las pacientes estaban asintomáticas en la esfera CV. FEVI basal: 63% (55-65), FEVI al momento de DV-TTZ: 49% (45-52) y porcentaje de descenso: 22,5% (16,1-26,2). Todas suspendieron transitoriamente TTZ e iniciaron enalapril (losartán si hubo intolerancia) y carvedilol. La normalización de la FEVI ocurrió en la totalidad de las pacientes al suspender el tratamiento con TTZ. El tiempo entre la DV-TTZ y la normalización de la FEVI fue de 49,5 días (28-166). La DV-TTZ se manifestó precozmente en dos pacientes (ciclos 5 y 6 TTZ) y en el resto entre los ciclos 10 y 15. Las pacientes con manifestación precoz demoraron más tiempo en recuperar la FEVI (119 y 166 días respectivamente). Luego de la normalización de la FEVI continuaron el tratamiento con TTZ manteniendo tratamiento cardioprotector. Conclusiones: en esta serie de casos observamos dos patrones diferentes de DV-TTZ, uno más precoz con mayor retardo en la recuperación de la FEVI. La DV-TTZ fue reversible y todas las pacientes pudieron continuar el tratamiento. Es intención del grupo de trabajo continuar investigando mediante estudios observacionales de cohorte y estudios clínicos randomizados para analizar los factores de riesgo para el desarrollo de DV-TTZ, así como posibles medidas de prevención.
Evaluating the possibilities of obtaining initial concentrates of rare earth elements (REEs) from fly ashes

J. Całus Moszko, B. Białecka, M. Cempa-Balewicz, H. Świnder, Central Mining Institute, Katowice, Poland The article presents the results of initial laboratory research into the possibilities of obtaining REE from fly ash from one of Polish powerhouses. In the work the authors have presented the results of investigations into the obtaining of initial REEs concentrations from fly ashes by physicochemical and hydrometallurgical methods. These investigations provide a basis for developing a technology of RRE recovery from fly ashes produced in the process of hard coals combustion.
Video assisted minimally invasive mitral valve replacement in rheumatic valve disease.

Objective: Assessment early outcome of video assisted minimally invasive mitral valve replacement, in rheumatic valve disease. Also, to evaluate early postoperative quality of life by SF 36 questionnaire. Methods: This is a prospective single center study which was conducted on 20 rheumatic heart patients, in Egypt; during the period from October 2015 to June 2018. The main pathological lesion was sever mitral regurgitation (MR), mitral stenosis (MS) or both. Patients underwent video assisted minimally invasive mitral valve replacement, through a right mini thoracotomy. 13 patients (65%) were via infra-mammary incision, 4 patients (20%) were via periareolar incision and 3 patients (15%) were via limited right anterolateral mini-thoracotomy. Results: Mean length of surgical incision was (6.60 ± 1.35 cm). Mean duration of operation, cardiopulmonary bypass, and cross clamp times were (4.32 ± 1.08 hr.), (2.85 ± 0.75 hr.) and (1.78 ± 0.47 hr.) respectively. ICU stay was 2.35 ± 1.14 days and Hospital stay was 6.45 ± 1.43 days. The mean amount of blood loss was 398.50 ± 245.79 ml with two patients of bleeding requiring re-opening. At discharge, all patients had normal mitral prosthetic valve function with no or trivial regurgitation, as shown by echocardiographic studies. The postoperative quality of life revealed faster recovery of usual activities. Conclusions: Video assisted minimally invasive mitral valve surgery in the surgically challenging rheumatic valve disease has less surgical trauma, blood loss and pain, which translates into short hospital stay, rapid return to normal activities, less use of resources.
Investigating the Correlation of Purchase Power Parity (PPP) with the Adopted Waste Management Method in EU28

The amount of Municipal Solid Waste (MSW) generated mostly in large urban centers is a major problem. For a modern society, the proper management and treatment of MSW is imperative and necessary. However, each community has organized and installed different waste treatment methods based on environmental, social and economic criteria. In this paper, a comparative analysis of waste treatment methods that countries in EU28 have adopted based on economic factors for a time period of 2008–2017, is presented. Power Purchase Parity (PPP), production of MSW and population growth have been considered as to identify how these factors may influence or determine the selected waste management methods. From the results obtained, what should be highlighted is the decrease of MSW in the majority of countries in EU28, regardless of population growth. PPP seems to have no correlation with more ecofriendly waste treatment methods such as recycling and composting, while countries that started to invest in waste-to-energy in the initial years of the examined period (2008–2017), increased their confidence in this technology up until the present day, regardless of PPP formulation.
Suicidal Ideation among Medical Students: An Integrative Review

Background: Suicide is more common among people who follow a medical career. This occurs because undergraduation course subjects students to psychologically strained situations, which can reduce their mental health and predispose them to suicidal ideation. Objectives: To analyze the factors related to suicidal ideation among medical graduates, highlighting depression and personality traits. To check stigmas surrounding suicidal ideation. Methodology: An integrative review study was carried out using the Scopus database (Elsevier). We selected studies published between 2014 and 2019, using two descriptors: "medical students" and "suicidal ideation". Results and Findings: 139 scientific articles were selected, of which 10 met the eligibility criteria. Specific personality traits and depression predispose to suicide. Although the stigma of suicide and substance use is greater among men, female gender, poor financial status, and psychiatric disorders increase depression scores. Students close to graduation are more likely to cope with stress than others. Limitations: The articles included in this work were produced using different methodologies and different measurement instruments. The prevalence of depression and suicidal ideation among students may be greater, given that stigma may favor the occurrence of response bias. Conclusion: Rates of suicidal ideation are very prevalent in medical students. To solve this problem, medical schools should take steps to prevent adverse situations.
ASA: Accelerating Sparse Accumulation in Column-wise SpGEMM

Sparse linear algebra is an important kernel in many different applications. Among various sparse general matrix-matrix multiplication (SpGEMM) algorithms, Gustavson’s column-wise SpGEMM has good locality when reading input matrix and can be easily parallelized by distributing the computation of different columns of an output matrix to different processors. However, the sparse accumulation (SPA) step in column-wise SpGEMM, which merges partial sums from each of the multiplications by the row indices, is still a performance bottleneck. The state-of-the-art software implementation uses a hash table for partial sum search in the SPA, which makes SPA the largest contributor to the execution time of SpGEMM. There are three reasons that cause the SPA to become the bottleneck: (1) hash probing requires data-dependent branches that are difficult for a branch predictor to predict correctly; (2) the accumulation of partial sum is dependent on the results of the hash probing, which makes it difficult to hide the hash probing latency; and (3) hash collision requires time-consuming linear search and optimizations to reduce these collisions require an accurate estimation of the number of non-zeros in each column of the output matrix. This work proposes ASA architecture to accelerate the SPA. ASA overcomes the challenges of SPA by (1) executing the partial sum search and accumulate with a single instruction through ISA extension to eliminate data-dependent branches in hash probing, (2) using a dedicated on-chip cache to perform the search and accumulation in a pipelined fashion, (3) relying on the parallel search capability of a set-associative cache to reduce search latency, and (4) delaying the merging of overflowed entries. As a result, ASA achieves an average of 2.25× and 5.05× speedup as compared to the state-of-the-art software implementation of a Markov clustering application and its SpGEMM kernel, respectively. As compared to a state-of-the-art hashing accelerator design, ASA achieves an average of 1.95× speedup in the SpGEMM kernel.
A hybrid circuit breaker based on current commutation approach for multi feeders DC railway substations

The paper presents an economic hybrid circuit breaker for limiting and interrupting the faults in DC railways substations. For fast fault current interruption, the hybrid breaker incorporates high speed mechanical contacts actuated by power semiconductor devices. Additionally, to avoid formation of electric arc, a commutation circuit is used to inject a counter current during fault interruption. In a real railway substation, each feeder is connected to the main DC bus through an expensive air magnetic DC circuit breaker and to an auxiliary DC bus through another expensive breaker. This leads to high cost especially in railway substation with multi feeders which are used to energize the vehicle transmission lines. In this paper, all DC breakers in DC railway substations are replaced by the suggested circuit breaker, which consists of a high speed mechanical contact with two semiconductor devices in each feeder and only one commutation circuit for injecting the counter current in all faulted feeders. The fault diagnosis is designed to detect the abnormal condition (current or voltage) in all feeders and direct the injected current from the commutation circuit to the faulted feeder only when the abnormal reaches a predetermine level. The suggested breaker is able to detect and interrupt any cascading of faults.
Role of the glycerophosphocholine acyltransferase, Gpc1, in phosphatidylcholine (PC) biosynthesis and remodeling in Saccharomyces cerevisiae

iv Acknowledgements.vi Common Abbreviations.xii Chapter 1: Introduction . xii 1.1. Saccharomyces cerevisiae as a model organism to explore membrane lipids . 1 1.2. Overview of the major classes of membrane lipids in S. cerevisiae . 2 1.3. Overview of phospholipid metabolism in yeast . 4 1.4. Regulation of UASINO-containing genes by the Henry regulatory circuit and other regulatory factors.8 1.5. Role of phospholipases, permeases, and glycerophosphodiesterases in phospholipid metabolism . 10 1.6. Classification of acyltransferases and transacylases involved in the metabolism of phospholipid . 12 1.7. A novel pathway for PC biosynthesis in bacterium, yeast and plants . 16 1.8. Acyl chain remodeling affects the phospholipid molecular species that impact physical properties of the membrane . 18 1.9. Significance of phospholipid remodeling for physiological functions in the higher eukaryotes . 21 1.10. Membrane lipids in bacteria and archaea. 22 1.11. Summary of background and significance . 23 Chapter 2: Cloning of glycerophosphocholine acyltransferase (GPCAT) from fungi and plants; a novel enzyme in phosphatidylcholine synthesis . 25 2.1. Abstract . 26 2.2. Introduction . 26 2.3. Results and discussion . 29 2.3. 1. Identification of the yeast GPCAT-encoding gene . 29 2.3. 2. Evolutionary analysis . 31 2.3. 3 ScGPCAT (Gpc1p) catalyzes the acyl-CoA-dependent acylation of GPC . 33 2.3. 4 Plant homologues of GPC1 catalyze acyl-CoA dependent acylation of GPC when expressed in yeast . 36 2.3. 5. Gpc1p catalyzes acylation of glycerophosphoethanolamine (GPE) with acyl-CoA . 38 2.3. 6. GPCATs from yeast and plants catalyze transacylation reactions . 38
MOLECULAR TYPING OF BULGARIAN SPECIMEN OF THE PHYTOPLASMA VECTORS CACOPSYLLA PRUNI SCOPOLI AND CACOPSYLLA MELANONEURA (FOERSTER)

EtropolskA, A. , W. JArAusch, B. JArAusch and g. trEnchEv, 2016. Molecular typing of Bulgarian specimen of the phytoplasma vectors Cacopsylla pruni scopoli and Cacopsylla melanoneura (foerster). Bulg. J. Agric. Sci., 22: 98–102 European fruit tree phytoplasmas diseases apple proliferation, pear decline and European stone fruit yellows are among the most important and rapidly spreading diseases in Bulgaria. their causal agents ‘Ca. phytoplasma mali’, ‘Ca. phytoplasma pyri’ and ‘Ca. Phytoplasma prunorum’ and their known and putative vectors have been identified in Bulgaria recently. This is the first report about the molecular characterisation of the phytoplasma vector species Cacopsylla pruni scopoli and Cacopsylla melanoneura (Foerster) in Bulgaria. The results confirmed the presence of Cacopsylla pruni type B in all Bulgarian samples and demonstrated a genetic variability among C. melanoneura specimen. For the first time, genetic variants WI and WOI were described outside Italy, but a relative high number of C. melanoneura could not be characterised by this molecular typing approach. Molecular identification of Cacopsylla affinis, a potential vector of different fruit tree phytoplasmas, proofed to be reliable.
Pengaruh Penanaman Modal Asing Jepang terhadap Perdagangan Intra-Industri Indonesia-Jepang

This study analyzes the effect of Japan’s foreign direct investment on Indonesia’s intra-industry trade (IIT) with Japan from 1990-2017. IIT is decomposed into 3 types, horizontal IIT (HIIT), upper vertical IIT (UVIIT), and lower vertical IIT (LVIIT) which indicates quality. The estimation result show that Japanese direct investment have a signiﬁcant role in enhancing bilateral IIT. Analysis on each type of IIT reveals that Japanese direct investment have positive signiﬁcant impact on HIIT and LVIIT, but there is no evidence on its impact to UVIIT. ================================== Penelitian ini menganalisis dampak penanaman modal asing (PMA) terhadap perdagangan intra-industri (IIT) Indonesia dengan salah satu mitra dagang utama yaitu Jepang, selama kurun waktu 1990–2017. IIT didekomposisikan menjadi 3 tipe, horizontal IIT (HIIT), upper vertical IIT (UVIIT), dan lower vertical IIT (LVIIT) yang mengindikasikan kualitas. Hasil estimasi menunjukkan PMA Jepang memiliki peran yang signiﬁkan untuk meningkatkan IIT bilateral kedua negara. Hasil analisis pada masing-masing tipe IIT menunjukkan bahwa PMA Jepang memiliki dampak positif signiﬁkan terhadap LVIIT dan HIIT, namun tidak terbukti memiliki dampak terhadap UVIIT.
A Simian View of the Oldowan

Findings from field primatology show that three living primate genera—ape (Pan), Old World monkey (Macaca), and New World monkey (Sapajus)—use elementary lithic technology to obtain and process food in nature. All three taxa use stone tools, producing enduring artifacts with distinctive archaeological signatures. In a comparison we show that each taxon has its own suite of tools, both organic and inorganic. All use percussion, but there are differences in the number and type of other tools in each taxon. Our assessment also allows for point-by-point comparisons with the early toolkits of extinct hominins, and here we compare to the Oldowan. This broader comparison shows that modeling the evolutionary origins of human material culture continues to advance. Wynn’s “ape adaptive grade” must now be expanded to a more inclusive “simian adaptive grade,” as monkeys too show convergent features with percussive stone technology.
More is not necessarily better: the impact of limiting and excessive nutrients on herbivore population growth rates

Abstract 1. The body tissues of insect herbivores contain higher concentrations of nitrogen and phosphorus than do their host plants, leading to an elemental mismatch that can limit herbivore growth, fecundity and ultimately influence population dynamics. While low nutrient availability can limit herbivore growth and reproduction, nutrient levels that exceed an organism’s nutritional requirements, i.e. an organisms’ threshold elemental ratio, can also decrease performance.
How to combine crop production and environmental quality? A decision support system to quantify best agri-environmental measures in the Veneto Region , Italy

Efforts have been made in Europe to support the adoption of agri-environmental measures (AEMs), with the ambition to combine both high standards of crop productivity and environmental quality. However, benefits from AEMs have been poorly quantified at the spatial scale, despite the increasing demand for a spatial-targeting approach that link site- specific payments with AEMs performance. The aim of this work was to develop an integrated model-GIS platform that was used as decision support system to evaluate best AEMs in terms of agronomic performance and agro-ecosystem quality. The study site was the Veneto Region, where the AEMs were applied from 2007 to 2013 according to the Rural Development Programme. Results showed that in general the continuous soil cover yielded both agronomic benefits and the improvement of environmental quality, while a change from mineral to organic fertilizations was effective in the long-term and in the loose soils of southern and western Veneto, improving the soil-water balance and the nutrients availability to the crops. These estimates provide a good starting point for decision-makers aiming to implement a spatial targeting approach that effectively evaluate the ecological effectiveness of agri-environmental policies.
The Effects of Brand Positioning Strategies on Consumers’ Brand and Category Perceptions: Some Insights from Schema Research

Results of four studies demonstrate that perceptions of how different a brand is from other brands in the product category affect perceptions of the brand's position within the category. Specifically, perceptions that a brand is strongly discrepant result in a subtyped (or niche) position, whereas perceptions that a brand is moderately discrepant result in a differentiated position within the general category. Perceptions of discrepancy are affected both by the extent of discrepancy on an attribute and whether the discrepant information is concentrated in a single ad for the brand or dispersed across multiple ads for the product. The effects associated with a subtyped position, in comparison with a differentiated position, are identified (study 1) and are found to increase with time (study 2). The subtyped versus differentiated distinction for a strongly versus moderately discrepant brand is validated with a sorting task (study 3). This distinction is shown to hold in the context of multiple discrepant brands that differ in their extent of discrepancy (study 4). Implications of the findings for a theoretical understanding of subtyping versus differentiation and for the application of positioning strategies in the marketplace are discussed.
Efficiency of teaching English vocabulary and grammar on the basis of assignments in IELTS format

This paper investigates the effects of teaching English vocabulary and grammar to EFL learners through the assignments in IELTS format. The authors designed a computer-based test to evaluate the efficiency of teaching English vocabulary and grammar on the basis of assignments in IELTS format. A pre-test and a post-test were the main instruments used for data collection. The participants of the study were made to do a post-test to assess their performance based on the vocabulary and grammar learning through the tasks in IELTS format. The results of t-test for correlated data proved that the training produced a positive effect on the EFL learners' results.