Miracle-dz/UniFAR-FTUs huggingface dataset:
Modeling dynamics of agile fixed-wing UAVs for real-time applications

A special class of fixed-wing UAVs called agile UAVs have emerged recently, that are lightweight with control surfaces as big as 50% chord capable of deflecting up to 50 deg. , and are characterized by high thrust-to-weight ratios of around 2-3, and a strong propwash. Such configuration allows agile UAVs to perform extreme aerobatic maneuvers that expand the conventional flight envelope to cover the full angle of attack and sideslip range. The desire to automate these aerobatic capabilities has led to a renewed interest in fixed-wing UAVs with a focus on understanding and modeling their dynamics for the full flight envelope. This paper presents a six degree-of-freedom dynamics model for agile UAVs obtained through first principles. Simple but accurate techniques are presented to model the aerodynamics, thruster dynamics and propeller slipstream effects, which are embedded into the overall UAV simulation that is setup to run both offline as well as in real-time with the pilot-in-loop. Static bench tests are performed for validation of the presented six-dof agile UAV model and underlying modeling techniques. As well, qualitative validation shows the model to successfully capture well-known RC maneuvers flown by an experienced pilot in real-time simulation.
A New Method for Virtual Machine Cluster Scheduling

Aiming at the reasonable configuration of virtual cluster and physical host, a new virtual machine cluster scheduling method is proposed. First of all, according to the resource requirements of the task, select the resource conditions similar to the virtual machine cluster. In the clustering process, the CPU, memory, communication bandwidth and other parameters are integrated in a measure under. Secondly, with the help of minimum flow and maximum cut theory, the virtual machine cluster is divided and configured to complete the scheduling process of virtual machine to the corresponding physical host. Experimental results show that the virtual machine cluster scheduling based on this new method makes the resource utilization of the physical host higher.
Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia

Acute lymphoblastic leukemia is the major pediatric cancer in developed countries. To date most association studies of acute lymphoblastic leukemia have been based on the candidate gene approach and have evaluated a restricted number of polymorphisms. Such studies have served to highlight difficulties in conducting statistically and methodologically rigorous investigations into acute lymphoblastic leukemia risk. Recent genome-wide association studies of childhood acute lymphoblastic leukemia have provided robust evidence that common variation at four genetic loci confers a modest increase in risk. The accumulated experience to date and relative lack of success of initial efforts to identify novel acute lymphoblastic leukemia predisposition loci emphasize the need for alternative study designs and methods. The International Childhood Acute Lymphoblastic Leukaemia Genetics Consortium includes 12 research groups in Europe, Asia, the Middle East and the Americas engaged in studying the genetics of acute lymphoblastic leukemia. The initial goal of this consortium is to identify and characterize low-penetrance susceptibility variants for acute lymphoblastic leukemia through association-based analyses. Efforts to develop genome-wide association studies of acute lymphoblastic leukemia, in terms of both sample size and single nucleotide polymorphism coverage, and to increase the number of single nucleotide polymorphisms taken forward to large-scale replication should lead to the identification of additional novel risk variants for acute lymphoblastic leukemia. Ethnic differences in the risk of acute lymphoblastic leukemia are well recognized and thus in assessing the interplay between inherited and non-genetic risk factors, analyses using different population cohorts with different incidence rates are likely to be highly informative. Given that the frequency of many acute lymphoblastic leukemia subgroups is small, identifying differential effects will realistically only be possible through multi-center pooled analyses. Here, we review the rationale for identifying genetic risk variants for acute lymphoblastic leukemia and our proposed strategy for establishing the International Childhood Acute Lymphoblastic Leukaemia Genetics Consortium.
Évaluation des anomalies thyroïdiennes biologiques et échographiques après allogreffe de cellules souches hématopoïétiques chez des enfants recevant un conditionnement à intensité réduite

Introduction : Le nombre de patients survivants apres une allogreffe de cellules souches hematopoietiques (CSH) realisee a l’âge pediatrique ne cesse de croitre. Il est donc indispensable de s’interesser aux toxicites a moyen et long terme d’un tel traitement. Un des enjeux des conditionnements a intensite reduite est de diminuer ces toxicites. Les dysfonctionnements endocriniens sont un exemple de sequelles parmi les plus frequents et bien connus des conditionnements classiques. Notre objectif principal est de decrire les anomalies thyroidiennes biologiques et echographiques chez les enfants allogreffes avec un conditionnement a intensite reduite. L’objectif secondaire est de rechercher les facteurs associes a l’apparition de ces anomalies. Materiel et methodes : Il s’agit d’une etude de cohorte descriptive, retrospective et mono- centrique. Nous avons inclus les patients survivants un an apres une allogreffe de CSH avec des conditionnements d’intensite reduite entre le 1erjanvier 2005 et le 31 decembre 2014. Pour chaque patient, nous avons analyse l’ensemble des bilans biologiques et echographiques thyroidiens realises au cours du suivi. Dans un deuxieme temps, les facteurs associes a l’apparition d’anomalies thyroidiennes biologiques ont ete recherches par un test du Chi2. Nous avons retenu comme seuil de significativite une valeur p < 0,05. Resultats : 54 patients ont ete inclus. L’âge median a la greffe etait de 7,5 ans (0,7-18,8). La duree mediane du suivi etait de 3,2 ans (1-10,5). Les pathologies rencontrees etaient des insuffisances medullaires (n=52) et des deficits immunitaires primitifs (n=2). L’incidence des dysthyroidies biologiques et echographiques au cours du suivi etaient de 32,6% et 31,2% respectivement. La majorite des anomalies biologiques etaient transitoires. Nous n’avons pas retrouve de cancer thyroidien secondaire. Aucun patient n’a manifeste de signes cliniques de dysthyroidie ni recu de traitement medicamenteux hormonal. Les facteurs associes a l’apparition d’une dysthyroidie biologique etaient le sexe feminin et la presence d’une GvH aigue. Ces resultats n’etaient cependant pas statistiquement significatifs. Conclusion : Des toxicites endocriniennes de l’allogreffe sont retrouvees malgre un conditionnement a intensite reduite. La presence d’une anomalie thyroidienne meme infra-clinique peut faire discuter la mise en place d’un traitement substitutif. Un suivi multidisciplinaire prolonge voire a vie chez ces patients a risque de sequelles sur le long terme est incontournable. L’etude de cohortes prospectives sur le long terme permettrait de degager des facteurs d’association significatifs.
Uncertainty-based test planning using dempster-shafer theory of evidence

During new product development, the process of selecting and conducting testing activities is of vital importance for both product maturity enhancement as well as test economics. To date, there are only few approaches providing quantitative decision support on test selection. In the present paper, a new methodology for prioritizing testing activities during test planning based on uncertainties in technical risk assessment is proposed. By analyzing prevailing uncertainties in risk assessment using the FMEA method, quantitative decision support for test case prioritization can be provided. The methodology is based on the common methodological framework for uncertainty modeling as well as recent approaches using Dempster-Shafer theory of evidence.
Alteration in myosatellite cell commitment with muscle maturation

Myosatellite cells are myoblasts found between the basal lamina and sarcolemma of myofibers of postnatal mice. The extent to which these cells are programmed, upon differentiation, to express isoforms of contractile protein genes specific to the type of fiber with which they are associated has been evaluated in vitro using myosatellite cells derived from the soleus and the extensor digitorum longus muscles (EDL) of 4‐day‐old and adult transgenic mice, which express nuclear localizing β‐galactosidase (nlsβ‐gal) under the control of the promoter and 3′ enhancer of the gene encoding fast myosin light chain 3F (MLC3F) (Kelly et al. [1995] J. Cell Biol. 129:383–396). Cultures were allowed to differentiate either as myocytes (mononucleated cells), to prevent possible modification of the myosatellite phenotype by other myonuclei in mosaic myotubes, or as myotubes. Transgene expression was age related, with 90% and 70% of the myocytes derived from the neonatal EDL and soleus muscles (muscles that had not yet achieved their mature phenotype), respectively, having nuclei encoding β‐gal; 61% and 32% of the myocyte nuclei derived from myosatellite cells of the adult EDL (a fast muscle) and the adult soleus muscle (a mixed muscle containing many slow myofibers), respectively, expressed this transgene. Because myosatellite cells found in adult muscles are the progeny of those found in the neonate, an alteration of myosatellite cell commitment to express this transgene occurs with muscle maturation. Because expression of the transgene in neonatal and adult muscle in vivo reflects the expression of the endogenous MLC3F gene (Kelly et al. [1995] J. Cell Biol. 129:383–396), it is likely that expression of the transgene by differentiated myosatellite cells reflects the extent of commitment of these cells to produce MLC3F. A hypothesis is presented that MLC3F is widely expressed in developing muscles but eliminated in myofibers that undergo maturation toward a slower phenotype. Dev. Dyn. 1998;211:141–152. © 1998 Wiley‐Liss, Inc.
American College of Sports Medicine Roundtable on Exertional Heat Stroke - Return to Duty/Return to Play: Conference Proceedings

On October 22-23, 2008, an ACSM Roundtable was convened at the Uniformed Services University (Bethesda, MD) to discuss return-to-play or return-to-duty for people who have experienced exertional heat illness (EHI) and to develop consensus-based recommendations. The conference assembled experts from the civilian sports medicine community and the Department of Defense to discuss relevant EHI issues, such as potential long-term consequences, the concept of thermotolerance, and the role of thermal tolerance testing in return-to-play decisions. Although the group was unable to move forward with new consensus recommendations, they clearly documented critical clinical concerns and scientific questions, including the following: 1) no uniform core definitions of EHI; 2) limited validated criteria to assess recovery from exertional heat stroke (EHS); and 3) inadequate ability to predict who may be predisposed to a subsequent heat injury after EHS. Areas of potential future research are identified.
Multipactor RF Breakdown in Coaxial Transmission Lines With Digitally Modulated Signals

The aim of this paper is the study of the RF multipactor breakdown in coaxial transmission lines excited by a single carrier with a digitally modulated signal. Employing an in-house developed code, numerical simulations are performed to determine the RF multipactor voltage threshold for several digitally modulated signals under different modulations schemes: quadrature phase-shift keying, 16-quadrature amplitude modulation, 16-amplitude and phase-shift keying, and 32-amplitude and phase-shift keying. Moreover, a coarse method based on the envelope integration to determine the RF multipactor voltage threshold when involving arbitrary digital modulations is also presented. These results are also compared with the “20-gap-crossing” rule used in the space standard document ECSS-E20-1A. In order to validate the theoretical results, a test campaign was performed for realistic modulated signals, finding good agreement between theoretical predictions and experimental data.
Manufacturing Practices and Strategy Integration: Effects on Cost Efficiency, Flexibility, and Market-Based Performance

Manufacturing plant managers have sought performance improvements through implementing best practices discussed in World Class Manufacturing literature. However, our collective understanding of linkages between practices and performance remains incomplete. This study seeks a more complete theory, advancing the idea that strategy integration and enhanced manufacturing capabilities such as cost efficiency and flexibility serve as intermediaries by which practices affect performance. Hypotheses related to this thesis are tested using data from 57 North American manufacturing plants that are past winners and finalists in Industry Week's“America's Best” competition (Drickhamer, 2001). The results suggest that strategy integration plays a strong, central role in the creation of manufacturing cost efficiency and new product flexibility capabilities. Furthermore, strategy integration moderates the influences of product-process development, supplier relationship management, workforce development, just-in-time flow, and process quality management practices on certain manufacturing capabilities. In turn, manufacturing cost efficiency and new product flexibility capabilities mediate the influence of strategy integration on market-based performance. These findings have implications for practice and for future research.
Soft Decision Equalization of Multiple Antenna Systems over Dispersive Channels Via Max-Log-Map Sphere Decoder

In this paper, we propose a multistage soft decision equalization (SDE) technique using max-log-MAP sphere decoder (MLMSD) for block transmission over frequency selective multi-input multi-output (MIMO) channels. Using the Toeplitz structure of the channel matrix, we convert the general signal model into a series of small-sized sub-signal models. We propose to use MLMSDs based on these sub-models to iteratively cancel interferences and get the estimations of the transmitted symbols. Simulation shows that when the block size is large, the proposed algorithm outperforms the Schnorr-Luchner sphere decoder and the probability data association SDL with a reasonable computational complexity in full-rank MIMO channels
Selfish routing and the price of anarchy

Selfish routing is a classical mathematical model of how self-interested users might route traffic through a congested network. The outcome of selfish routing is generally inefficient, in that it fails to optimize natural objective functions. The price of anarchy is a quantitative measure of this inefficiency. We survey recent work that analyzes the price of anarchy of selfish routing. We also describe related results on bounding the worst-possible severity of a phenomenon called Braess's Paradox, and on three techniques for reducing the price of anarchy of selfish routing. This survey concentrates on the contributions of the author's PhD thesis, but also discusses several more recent results in the area.
Multiple extra macular branch retinal vein occlusions in hyperhomocysteinemia

Hyperhomocysteinemia is a well-known modifiable risk factor for thromboembolism. Retinal vascular occlusion in patients having hyperhomocysteinemia is a known entity, particularly in young patients. However, multiple extra macular branch retinal vein occlusion (BRVO) is a rare condition, which can be a presentation of this disease. We present a patient who had multiple extra macular BRVO; on complete systemic workup, he was found to have raised homocysteine levels.
Twelve-month service utilization rates for mental health reasons: data from the Israel National Health Survey.

OBJECTIVE To measure the 12-month utilization rates for mental health reasons in all types of services. METHOD A representative sample extracted from the National Population Register of non-institutionalized residents aged 21 or older were interviewed at their homes between May 2003 and April 2004. DSM-IV disorders were assessed using a revised version of the Composite International Diagnostic Interview (WMH-CIDI). RESULTS About 10% of the adult population receives some type of treatment for emotional or mental health problems within a single year. More than half of service consumers were not classified as suffering from mood or anxiety disorders. Of those diagnosed with mood or anxiety disorders in the past 12 months only about 50% used any type of service for mental health problems. CONCLUSION There is only a partial overlap between those who utilize the services and those who meet the criteria for a clinical diagnosis of mental disorder.
Performance analysis of OFDM based full duplex cognitive AF relay network in the presence of narrowband interference

In this paper, outage and the average Bit Error Rate (BER) performance of the Orthogonal Frequency Division Multiplexing (OFDM) based full duplex Cognitive Radio (CR) relay network is analyzed in the presence of Narrowband Interference (NBI). Assume the NBI signal to be quasi-static over one OFDM signal. The full duplex relay employs Amplify and Forward (AF) relaying strategy to improve the output Signal to Interference plus Noise Ratio (SINR) at the destination node. Analytical expressions are derived for the outage probability and the end-to-end average BER of the full duplex AF relay network in the presence of NBI. The network performance is compared with half duplex mode.
Essentiality of Mitochondrial Oxidative Metabolism for Photosynthesis: Optimization of Carbon Assimilation and Protection Against Photoinhibition

Referee: Christine Foyer, Dept. of Biochemistry and Physiology, IACR - Rothamsted, Harpemden, Herts AL5 2JQ, England, United Kingdom The review emphasizes the essentiality of mitochondrial oxidative metabolism for photosynthetic carbon assimilation. Photosynthetic activity in chloroplasts and oxidative metabolism in mitochondria interact with each other and stimulate their activities. During light, the partially modified TCA cycle supplies oxoglutarate to cytosol and chloroplasts. The marked stimulation of O2 uptake after few minutes of photosynthetic activity, termed as light enhanced dark respiration (LEDR), is now a well-known phenomenon. Both the cytochrome and alternative pathways of mitochondrial electron transport are important in such interactions. The function of chloroplast is optimized by the complementary nature of mitochondrial metabolism in multiple ways: facilitation of export of excess reduced equivalents from chloroplasts, shortening of photosynthetic induction, maintenance of photorespiratory activity, and supply of ATP for sucrose biosynthesis as well as other cytosolic needs. Further, the mitochondrial oxidative electron transport and phosphorylation also protects chloroplasts against photoinhibition. Besides mitochondrial respiration, reducing equivalents (and ATP) are used for other metabolic phenomena, such as sulfur or nitrogen metabolism and photorespiration. These reactions often involve peroxisomes and cytosol. The beneficial interaction between chloroplasts and mitochondria therefore extends invariably to also peroxisomes and cytosol. While the interorganelle exchange of metabolites is the known basis of such interaction, further experiments are warranted to identify other biochemical signals between them. The uses of techniques such as on-line mass spectrometric measurement, novel mutants/transgenics, and variability in metabolism by growth conditions hold a high promise to help the plant biologist to understand this interesting topic.
Likelihood analysis of spatial capture-recapture models for stratified or class structured populations

We develop a likelihood analysis framework for fitting spatial capture-recapture (SCR) models to data collected on class structured or stratified populations. Our interest is motivated by the necessity of accommodating the problem of missing observations of individual class membership. This is particularly problematic in SCR data arising from DNA analysis of scat, hair or other material, which frequently yields individual identity but fails to identify the sex. Moreover, this can represent a large fraction of the data and, given the typically small sample sizes of many capture-recapture studies based on DNA information, utilization of the data with missing sex information is necessary. We develop the class structured likelihood for the case of missing covariate values, and then we address the scaling of the likelihood so that models with and without class structured parameters can be formally compared regardless of missing values. We apply our class structured model to black bear data collected in New Yor.
Cognitive-Affective Correlates and Predictors of Superficial Dyspareunia

This study investigated the role of cognitive-affective variables related to sexuality, chronic pain, individual and relational well-being in superficial dyspareunia. Although symptomatic women (n = 80) differed from complaint-free controls (n = 62) on all variables, sexuality related measures had the most important contribution into the prediction of group membership. Dyspareunia subgroups based on the presence/absence of a concomitant diagnosis of provoked vestibulodynia were only distinguishable on pain intensity but not on variables related to sexuality and psychological well-being. The present findings underscore the relevance of psychosexual factors in women with superficial dyspareunia.
Unbiased evaluation of keypoint detectors with respect to rotation invariance

The authors present the results of a comparative performance study of algorithms for detecting keypoints in digital images. The Harris, good features to track (GFTT), SIFT, SURF, FAST, ORB, BRISK, and the MSER keypoint detectors were tested using two types of images: POV-Ray simulated images and photographs from the Caltech 256 image dataset. They tested the repeatability of detection of the image keypoints for the evaluated detectors for a series of images with one degree rotations from 0 to 180° (3982 images in total). In the evaluation scenario they adopted an original approach in which they did not hold back a single image to be the reference image. They conclude that the most computationally complex detector, i.e. the SIFT performs best under rotation transformation of images. However, the FAST and ORB detectors, while being less computationally demanding, perform almost equally well. Hence, they can be viable choices in image processing tasks for mobile applications.
Ecology of pathogenic yeasts in Amazonian soil

In an investigation of Amazonian soil as a natural reservoir for pathogenic fungi, 1,949 soil samples collected from diverse geographical and ecological settings of the Brazilian Amazon Basin were analyzed for the presence of non-keratinophilic fungi by the indirect mouse inoculation procedure and for the presence of keratinophilic fungi by the hair bait technique. All soil samples were acidic with low pH values. From 12% of the soil samples, 241 yeast and yeastlike isolates pertaining to six genera and 82 species were recovered, of which 63% were Torulopsis and 26% were Candida species. Nine fungi with known pathogenic potentials were encountered among 43% (104) of the isolates: T. glabrata, C. guilliermondii, C. albicans, C. pseudotropicalis, C. stellatoidea, C. tropicalis, Rhodotorula rubra, and Wangiella dermatitidis. The yeast flora was marked by species diversity, low frequency of each species, random geographical distribution, and an apparent lack of species clustering. The composition and distribution of the yeast flora in soil differed from those of the yeast flora harbored by bats, suggesting that the Amazonian external environment and internal bat organs act as independent natural habitats for yeasts.