Miracle-dz/UniFAR-FTUs huggingface dataset:
The Determinants of Merger Withdrawals’ Abnormal Returns in The Australian Market

This paper examines the abnormal returns in merger withdrawals in Australia, especially distinguishing the market response between private and public targets. We also study the determinants of those abnormal returns, including the method of payment and the impact of financial crisis periods. Using the event study method, we document that in the Australian context, the announced withdrawal of mergers involving private targets creates significantly negative valuation effects in comparison with the valuation effects in withdrawal of mergers involving public targets. We also find that a financial crisis period strongly affects abnormal returns of merger withdrawals. However, the method of payment does not have any impact on the abnormal returns.
A Stream Learning Intrusion Detection System for Concept Drifting Network Traffic

Network-based intrusion detection is a widely explored topic in the literature. Yet, despite the promising reported results, designed schemes are rarely used in production environments. Apart from evolving as time passes, the behavior of network traffic varies significantly, rendering proposed schemes unreliable for real-world application. This paper proposes a new stream learning intrusion detection aiming for feasible model updates, implemented in three phases. First, intrusion detection is performed through a stream learning classifier, enabling incremental model updates to be performed. Second, new network traffic behavior is identified through a one-class learner. Third, identified new network traffic is incrementally incorporated into our system. Experiments performed on a dataset containing evolving network traffic behavior have shown our proposal feasibility, reaching up to 96% of accuracy while demanding only 48% of labeled events to be provided.
Adaptation in Patients with Diabetes Mellitus Type 2, According to the Roy Model

Purpose. To determine the influence between focal and contextual stimuli and the physiological and psychosocial adaptation in people with DMT2. Material and Method. The design was descriptive, cross, predictive. The sampling was probabilistic, systematic. The sample with 200 participants of both genders from 30 to 65 years, was determined for 95% of confidence, with a test power of 90%. Results. The results showed that years of diagnosis explained the physiologic adaptation F (1,198) = 9.18, p = . 003. Effect was observed between complications and psychosocial adaptation F (4,195) = 4.97, p = . 001, with a coefficient of determination of 74%. The contextual stimuli influenced in the physiological and psychosocial adaptation, F (6,193) = 2.89, p = . 010, and F (6, 193) = 2.41, p = . 029. Conclusions. The results of this study allowed testing theoretical propositions derived from the Roy Adaptation model particularly between stimuli and the physiological and psychosocial adaptation in patients with type 2 diabetes mellitus.
Research on 5G Interference Auto-Optimization

In the early stage of 5G network construction, the network suffers from user access difficulties, low user Internet access rates, and poor VoNR call quality due to interference. Therefore, interference investigation is crucial in the initial network construction stage. However, the analysis and investigation of interference consume many human resources, the investigation cycle is long, and the efficiency is low. Studying a method that can improve the investigation efficiency and reduce network optimization costs is essential. This paper systematically studies the interference sources of the 5G network. An innovative 5G interference automatic optimization process is proposed based on big data and AI models, and prototype products are developed and piloted. The verification and test results show that the scheme proposed in this paper can effectively improve the efficiency of 5G external interference investigation and positioning.
Quantum Dots Targeted to VEGFR2 for Molecular Imaging of Colorectal Cancer

Advances in optical imaging have provided methods for visualizing molecular expression in tumors in vivo, allowing the opportunity to study the complexity of the tumor microenvironment. The development of fluorescent contrast agents targeted to molecules expressed in cancer cells is critical for in vivo imaging of the tumors. Contrast agents emitting in the near infrared (NIR) allow for an increased depth of penetration in tissue due to decreased absorption and scattering. There is also significantly less autofluorescence from tissue in the NIR. Quantum dots are nanoscopic particles of semiconductors whose fluorescent emission wavelength is tunable by the size of the particle with desirable fluorescent qualities such as a wide range of excitation wavelengths, a narrow emission band, high quantum efficiency, high photostablility, and they can be produced to emit throughout the NIR imaging window. It has been shown that vascular endothelial growth factor receptor 2 (VEGFR2) is upregulated in many cancers, including colorectal, as it is important in tumor angiogenesis and is considered a predictor for clinical outcome and, in some instances, is used for targeted therapy with anti-angiogenic drugs. For these reasons, quantum dots bioconjugated to VEGFR2 antibodies have the potential to provide contrast between normal tissue and cancer, as well as a mechanism for evaluating the molecular changes associated with cancer in vivo. In this dissertation, we present on the design of two contrast agents using quantum dots targeted to VEGFR2 for use in the molecular imaging of colon cancer, both ex vivo and in vivo. First, as a preliminary ex vivo investigation into their efficacy, Qdot655® (655nm emission) were bioconjugated to anti-VEGFR2 antibodies through
Adipokines and bone: enigma or paradigm?

Despite years of intense research in the field of adipokines and musculoskeletal system, there is still an open debate over the effect of certain adipokines, particularly leptin and adiponectin, on this system. Though, adipokine effects on bone turnover and density are still under deep investigation. Adipobiology 2011; 3: 51-52.
Immune modulation in sepsis

Abstract The vast majority of morbidity and mortality from sepsis can be attributed to the host immune response to infection rather than the infection itself. The innate and adaptive immune systems both contribute to this process. Numerous therapies aimed at reducing the pro-inflammatory burden of acute sepsis have been studied in clinical trials, with most producing disappointing results. The inflammatory response to sepsis has since been shown to be highly dynamic, with a period of compensatory down-regulation of the pro-inflammatory response dominating in the subacute phase of illness. This state, when prolonged and severe, is termed immunoparalysis and is associated with increased risks for nosocomial infection and death. Early evidence suggests that this state may be reversible with beneficial effects on outcomes. Other strategies for manipulating the inflammatory response in the setting of sepsis include the use of corticosteroids, immunonutrition, extracorporeal therapies, intravenous immunoglobulin, and the modulation of pre-existing immunosuppressive drugs. Clinical trials investigating immune modulation in sepsis have largely been done without the benefit of prospective immune monitoring and have rarely been done in children. Immune phenotype-directed therapies aimed at restoring immunologic homeostasis in pediatric sepsis represent the next step on the path toward improving sepsis outcomes in children.
Scientific Opinion on the Neste Oil Application for a new alternative method of disposal or use of Animal By-Products

EFSA’s Scientific Panel on Biological Hazards (BIOHAZ) was asked for a scientific opinion on a novel process developed by the Neste Oil Company as a safe means of disposal of animal by-products (ABP) according to Regulation (EC) 1774/2002. It is proposed that the method, known as the “Renewable Fuel” method, will be used for the treatment and disposal of Category 1 and Category 2 rendered animal fat obtained from animal byproducts that have been produced according to processing method 1 as referred to in Annex V, Chapter III of Commission Regulation (EC) 1774/2002 and for the treatment of Category 3 rendered animal fat that has been produced according to any of the processing methods 1 to 7 as referred to in the same Annex. The proposed process technology consists of a pre-treatment and of a continuous multiple step catalytic process. The main steps of interest for this assessment are called hydrodeoxygenation and isomerisation by the applicant. The production process can utilize a mixture of vegetable-oil and animal fat as feedstock. The Panel concluded that, in principle, the “Renewable Fuel” method may be appropriate for the safe destruction of BSE/TSE infectivity in animal waste. However, the company provided minimal data to support this conclusion (e.g. no quantitative estimate of the risk reduction level for Cat. 1 material was given). In the absence of such supporting data, the “Renewable Fuel” method cannot be considered safe for the treatment of such Category 1 wastes. The process proposed by Neste Oil can be considered to be safe for the treatment of Cat. 2 and 3 rendered animal fat since the input materials have already undergone a process ensuring adequate risk reduction
Consumers' Nutritional Ratings of Fast-Food Meals

Recent developments in the area of the nuiritional value of fast-food meals are discussed in this exploratory paper. The work by McNeal, Stem, and Nelson on consumers' ratings of meals is reviewed. Changes made by fast-food chains are summarized, then followed by a discussion on whether or not these changes represent an improvement in nutrition. Finally, the authors discuss findings from a replication of the McNeal et al. study and compare them to those from the original study.
A comparative study on plant classification using convolutional neural networks architectures

Determining the species of a plant is important to know its ecological and economic importance. Recently, deep learning (DL) models, specifically convolutional neural networks (CNN), have achieved outstanding results in several applications, including the classification of plants. This work focused on the evaluation and compassion of transfer learning models: Alexnet, VGG-16, ResNet-18, ResNet-50, DenseNet, and Inception V3. The datasets used were the Peruvian Forestry Amazon dataset and PlantVillage. For the training, therefore, we used two instances. We evaluated the models by different multiclass metrics: accuracy, sensitivity, precision, F-score. The results present significant values obtained by the VGG-16 model, with 97,79% accuracy, 98,00% sensitivity, 98,00% precision, and 98,00% F-score to the Peruvian Forestry Amazon dataset. It is possible to conclude that the VGG-16 model got an acceptable level of accuracy, which makes it a useful tool to help classify plant species from the Amazon.
Unificar los criterios de sepsis neonatal tardía: propuesta de un algoritmo de vigilancia diagnóstica

Las infecciones constituyen una de las principales causas de muerte en el periodo neonatal. El diagnostico de sepsis neonatal representa un gran desafio ya que los recien nacidos presentan signos clinicos muy inespecificos y los examenes auxiliares tienen una baja sensibilidad. Con el objetivo de mejorar el diagnostico correcto de esta patologia proponemos un algoritmo de vigilancia diagnostica para sepsis neonatal tardia en el Peru y paises de la region. El algoritmo permite clasificar a los episodios como sepsis confirmada, probable o posible, y sobre todo busca identificar aquellos episodios que no corresponden a sepsis, evitando calificar otras patologias como “sepsis”. Un mejor diagnostico permitiria tener tasas mas reales de sepsis neonatal, mejorar el uso de antibioticos y evitar sus efectos negativos en el recien nacido, asi como una vision mas exacta de su impacto en la salud publica
Drink and British Politics Since 1830. A Study in Policy-Making

Alcohol is one aspect of twentieth-century British popular culture that has received comparatively little attention. While other specific items of consumption cars, music halls, the cinema, seaside holidays, and so on have received sustained scholarly treatment in one or more monographs each, the central role of the public house in everyday life has not been reflected in the historical literature. Undoubtedly, aspects of twentieth-century drinking have received some attention. Gourvish and Wilson have provided a comprehensive study of the brewing industry. (1) Burnett has placed beers, wines and spirits alongside a range of other liquid refreshments over a much longer time-scale. (2) Barr, too, has covered the century within a much longer historical framework in his social history of drink. (3) And specific aspects of alcohol, such as the relationship between addiction and social policy, have more recently been explored in great depth. (4) But twentieth-century drink in all its historical manifestations its regulation, distribution, social role, cultural significance, medical effects has not been the subject of a specific work.
Instrumentos de avaliação clínica e funcional em cirurgia da coluna vertebral

Alguns dos individuos submetidos a cirurgia de coluna vertebral terao desfechos pos-operatorio desfavoraveis, independente do exito tecnico. Esse insucesso gera aumento da morbidade e dos custos socioeconomicos. Sabe-se que fatores psicossociais interferem na impressao do sujeito. Com o proposito de identifica-los, tem-se estimulado a busca de preditores prognosticos por meio de instrumentos de triagem. Porem, a eleicao do mais adequado pode ser dificil, ja que existe um grande numero de questionarios. Entre os aspectos abordados por eles, podemos citar: incapacidade funcional, qualidade de vida, satisfacao, dor, depressao, disturbios do humor e atividade funcional. O trabalho objetiva revisar as particularidades, indicacoes e limitacoes dos instrumentos de avaliacao do paciente com doenca na coluna vertebral.
Evidence-Based Treatments for Substance Use Disorders

A wide variety of evidence-based psychotherapies and pharmacotherapies demonstrate efficacy and effectiveness in the treatment of substance use disorders. Among recent developments in behavioral therapies are expanded uses of contingency management and developments in pharmacotherapies including a new opioid agonist therapy. Studies show superiority in combinations of therapies, such as contingency management to enhance compliance with naltrexone for alcohol dependence. Choice of treatment should be based primarily on the needs of the individual client, within the constraints of a treatment program’s service array and capacity of clients to pay for services. For persons with severe addictions and complex medical and psychosocial problems, a comprehensive service package with continuing care and monitoring is essential.
Blind Navigation: Technologies for Visually Impaired

s--Blindness is a condition in which an individual loses the visual recognition. Mobility and self-reliability for the blind has dependably been an issue. A considerable measure has been made to propel advances that enhance blind and partial sighted individua l’s spatial observation. Many surveys of various technologies of navigation system for visually impaired with their usefulness, design and working according to the requirement of blind people is conducted. Current innovation gives applications to be proficiently appropriated and keep running on versatile and hand-held gadgets, even in cases wherever unique procedures are vital. Electronic travel aids navigation modules, text-to-speech applications, with added advancement in the technology are getting integrated into normal mobile devices. These technologies combined with continuous simple interfaces and methods of collaboration has opened a scope of most recent perspectives for the restoration and being easy to use of people with visual impairment. In general, it can be summarized to those technologies supporting the visually impaired with basic analysis and application development. This can provide better understanding of the technologies and their further analysis for future research.
Evaluation of Negative Malaria Giemsa-Stained Smears Referred from Malaria Centers in Sistan and Balouchestan Using Nested Polymerase Chain Reaction

Article history: Received: 17 Dec 2012 Accepted:. 26 Dec 2012 Available online: 26 Feb 2013 ZJRMS 2014; 16(4): 15-18 Background: Malaria is one of the most important infectious diseases worldwide and also in Iran. Reports announced by Controlling Diseases Center (CDC) prove the presence of two species including Plasmodium vivax and Plasmodium falciparum in this province. P. falciparum cases diagnosis in purpose of true treatment and following up patients is necessary. This study is intending to extract DNA from negative microscopic smears using the newly invented method by research group and afterwards to evaluate negative malaria Giemsa-stained smears using nested polymerase chain reaction. Materials and Methods: Aiming to diagnose malaria, nested PCR amplification was accomplished using DNA extracted from fixed negatively diagnosed microscopic smears and Giemsa-stained. The extracted DNA was used as a pattern to amplify the specific sequence of P. falciparum and P. vivax using the small subunit of ribosomal RNA [18ssrRNA]. This retrospective study was implemented on 500 malaria negative microscopic smears storing from 6 months to 1 year. Results: By accomplishing PCR amplification on 500 microscopic smears, 54 (10.8%) malaria positive samples were diagnosed which were incorrectly diagnosed to be negative previously. Of all specimens revealed to be positive, 34 (6.8%) cases were P. vivax while 20 (4%) cases were P. falciparum. Conclusion: This study reveals the priority of nested-PCR method to microscopic examination method and the possibility of using old microscopic smears in epidemiologic and retrospective studies clearly. Copyright © 2014 Zahedan University of Medical Sciences. All rights reserved.
Metaphor

metaphor 这一英语辞格,译作“暗喻”或“隐喻”,事实上,它比汉语辞格“暗喻”包括的范围要广得多,它涉及了汉语中的“暗喻”、“借喻”、“比拟”、“转类”、“移就”等修辞方式,对于深受汉语影响的初学者来说,往往对其辨认不清,张冠李戴,有时甚至当作一般语法现象看待,这必然影响对原文的正确理解,就更谈不上去欣赏了。
De mediadores a protagonistas : crisis política, medios y comunicación en Venezuela

En el presente trabajo academico se estudiara el protagonismo de los medios de comunicacion en el conflicto politico venezolano durante dos episodios: el frustrado golpe de Estado de abril de 2002 y el “paro civico” opositor que se extendio durante dos meses desde el 2 de diciembre de 2002. Como se vera, el debate esta centrado en la polarizacion politica en torno a la figura del presidente Hugo Chavez. Para esto se analizara el contexto que ubique a protagonistas y actores, a lo cual debe anadirse una vision sobre los distintos elementos que estan en juego.
El ictus en el siglo XXI. Tratamiento de urgencia

La enfermedad vascular, una verdadera epidemia, es la primera causa de muerte en los paises desarrollados, responsable de mas de una cuarta parte de las muertes documentadas a nivel mundial y la primera causa de discapacidad grave en el adulto. Las tres cuartas partes de los ictus afectan a pacientes mayores de 65 anos, y debido a las previsiones de poblacion en las que Espana sera en el 2050 de las poblaciones mas envejecidas del mundo, se preve un incremento de la incidencia de esta patologia en los proximos anos. Numerosos estudios describen el escaso conocimiento de la poblacion, sobre los signos y sintomas de presentacion del ictus. Se recomienda elaborar campanas informativas orientadas a la poblacion general para aumentar su conocimiento sobre los factores de riesgo, facilitar la identificacion de los signos y sintomas de alarma y fomentar entre los pacientes el concepto del ictus como urgencia neurologica. El Codigo Ictus permite un rapido proceso de identificacion, notificacion y traslado de los pacientes a los servicios de urgencia hospitalarios. Los avances tecnologicos en el diagnostico y la aparicion de medidas terapeuticas eficaces, tromboliticos, hacen necesaria la organizacion coordinada y multidisciplinar. La Unidad de Ictus es la aproximacion mas eficaz y eficiente en el manejo de la fase aguda del ictus isquemico o hemorragico. Los progresos en la investigacion permitiran disponer de nuevas y mejores oportunidades para el tratamiento agudo del ictus.
The development of old age psychiatry in the Czech Republic

Geriatric medicine has a long tradition in the Czech Republic. In 1843, Hamernik gave the first lecture on geriatrics at Charles University in Prague; somewhat later in 1923 the first University Geriatric Clinic was founded in that city. The Czech Psychogeriatric Association was founded in 1968, making it one of the oldest societies of its type in Europe. Prague has contributed some famous figures to the history of old age psychiatry, of which the most outstanding is Arnold Pick (1851-1924), who was Chairman of the German department of the Prague Psychiatric Clinic from 1886-1921. His main interest was clinical neuropathology, and he is remembered for the discovery of the ‘Picks bundle’ in the medulla oblongata (1898), and for the frontal lobe dementia that also bears his name (1892). In fact, only two of his original cases suffered from ‘Pick’s disease’; the other four proved to have other forms of dementia. He also described ‘Pick’s pontine visions’, hallucinations caused by brain stem lesions (1908). Another citizen of Prague who has made important contributions to psychogeriatric research is Vojtech Adalbert Kral. He graduated from Charles University in 1927, and was a member of the psychiatric staff from 1928-1938, becoming Professor of Psychiatry in the German department of the Psychiatric Clinic in 1939. He and his wife (an ophthalmologist) survived internment in Auschwitz during the Second World War, following which he became director of a private mental hospital in Prague. After the Communist revolution he moved to Montreal in 1949, to become one of the founders of Canadian psychogeriatrics. Kral is best known for his concepts of ‘masked depression’ (1 958) and ‘benign senescent forgetfulness’ (1962) in the elderly. The latter has been
Skin biopsy as an alternative to muscle biopsy for the diagnosis of Ullrich congenital muscular dystrophy

Abstract The aim of this study was to assess the diagnostic utility of skin biopsy in the diagnosis of Ullrich congenital muscular dystrophy. Paired skin and muscle biopsies were, studied in the three cases of Ullrich disease. Immunostaining for collagen VI was performed on both test and control biopsies. Staining pattern in skin biopsies was compared with the muscle biopsies. Immunoblot was performed to validate the results. Immunostaining for collagen VI was absent in dermis in skin biopsies of all the three patients of Ullrich disease and corroborated with findings of muscle biopsies. Immunoblot revealed absence of collagen VI band in all the three cases. Our study suggests that skin biopsy can be very useful for the diagnosis of Ullrich disease. Skin biopsy being less traumatic and less invasive is easy to perform in children, obviates the need for sedation, and is cosmetically superior to muscle biopsy.
A Multiform Power Components Dataset for Robotic Maintenance in Power Grid

Power component maintenance plays an important role in power grid. Intelligent maintenance of power components using robots is a trend in smart grid. However, power components dataset is difficult to produce. especially for 6D pose estimation, which have not been found in recent years. Therefore, a novel dataset named power components pose dataset (PCPD) is proposed in this paper to assist power components maintenance by robot. PCPD consists of the raw data and label. The raw data contains RGB images, depth images and point clouds. Label involves semantic information, bounding box and 6D pose. Thus, semantic segmentation, object detection and pose estimation could be realized according to PCPD. In addition, it also can promote the effective application of intelligent robots in the field of smart grid.