Miracle-dz/UniFAR-FTUs huggingface dataset:
Pharmacokinetics of gallic acid from the topical ointments of standardized extracts of Chrysophyllum cainito and Mimusops elengi in rats

Introduction: The wound healing activity of leaves of Chrysophyllum cainito and flowers of Mimusops elengi has been reported through our previous studies. Therefore, the aim of this study was to evaluate pharmacokinetics of gallic acid from the ethanolic extracts of these plants and to support the findings of the preclinical study. Methods: A simple HPLC method was developed for detection of gallic acid in rat plasma post topical application of the ointments containing 20% ethanolic extracts of both the plants and validated as per USFDA guidelines. Clonidine hydrochloride was used as an internal standard (IS). Chromatographic separation of gallic acid and IS was achieved on Cosmosil C18-column using mobile phase [10 mM KH2PO4 in water: acetonitrile: orthophosphoric acid (95: 5: 0.05, v/v/v)] delivered at a flow rate of 1.0 mL/min. The ultraviolet detection wavelength was set at 215 nm. Results: The calibration curve was linear over a concentration range of 0.05-5.0 μg/mL. The method was found to be accurate, precise and stable for gallic acid from spiked plasma at QC levels. The average method recoveries for gallic acid were over 85% and extraction recoveries between 78 and 87%. Conclusion: The HPLC method was applied successfully to the pharmacokinetic study of gallic acid. The detection of gallic acid in rat plasma post topical application of ethanolic extracts of both the plants proves its absorption which probably facilitates the biochemical changes and thus exhibits wound healing activity of the plant extracts.
Nachhaltiges Management

The implementation of more sustainable management makes corporate decisions more complex. In this book, students and managers learn that it is the contradictory nature of management rationalities in particular that causes this complexity. These rationalities express themselves above all in the question of whether and how much a company should invest in the reproduction of ecological, economic and social resources, on which the company depends. In this respect, integral sustainability management 4.0 is based on an attitude that companies and the environment can adopt and narrate as a symbiotic and budgetary partnership.
Influence of Lead on In vitro Seed Germination and Early Radicle Development of Acacia auriculiformis Cunn. Ex Benth Species

Aims: To determine the impact of Pb on seed germination and early seedling development in A. auriculiformis species. Place and Duration of Study: The study was carried out in Department of Biology, University Putra Malaysia, between April 2016 and February 2017. Methodology: The concentrations of lead from 0 to 4 g/L (interval of 0.5 g/L) were used. Seeds were germinated in vitro condition. Different parameters were measured including germination percentage, seedling vigour index, tolerance index, germination index, mean germination time and relative injury rate. Results: The noticeable finding of this study reveals that A. auriculiformis seeds have the ability to Original Research Article Zerkout et al.; ARRB, 28(1): 1-12, 2018; Article no.ARRB. 43393 2 germination and resist Pb toxicity up to 1.5 g/L. Increasing Pb concentration from 1.5 to 3.5 g/L decreased the germination percentage from 57% to 4% respectively. Conclusion: Acacia auriculiformis seeds germination in a high level of Pb (up to 1.5 g/L) indicated species resistance which probably can be used as Pb hyperaccumulator agent in areas or sites contaminated with this metal.
Photolysis and Hydrolysis of Emamectin Benzoate and Its Degradation in Soils

An indoor simulation experiment was carried out to study photolysis and hydrolysis of emamectin benzoate in buffer solution,and degradation of emamectin benzoate in three different types of soils,black soil from Northeast China,red soil from Jiangxi and paddy soil from the Lake Taihu region.Results show that the photolytic half-life of emamectin benzoate in solution under the Xe lamp with optical intensity of 2 370 lx and ultraviolet radiation intensity of 13.5 μW·cm-2 was determined to be 1.73 h.In solution with temperature 25 ℃ and pH 5.0 and 7.0 emamectin benzoate was hard to hydrolyze and its half-life was reckoned to be over 1 year.However,it was easy to hydrolyze in solution of pH 9.0 with a half-life being 45.3 days,which was shortened in solution of higher temperature.The half-life of emamectin benzoate in red soil,black soil and paddy soil was 16.3,41.5 and 91.2 days,respectively,which was affected mainly by biodegradation and hence the content of soil organic matter.
Développement d'un procédé d'oxydation avancée pour le traitement d'effluents aqueux contaminés par des polluants réfractaires : étude d'un procédé de décharge plasma à pression atmosphérique couplé à un catalyseur supporté

Dans ces travaux de recherche nous avons cherche a developper et optimiser un procede d'oxydation avancee dedie au traitement de l'eau. Pour cela, nous avons developpe un procede combinant la generation de radicaux hydroxyles par decharge plasma a pression atmospherique et un catalyseur fixe. L'originalite de ce travail a ete d'utiliser un systeme d'ecoulement permettant l'obtention d'un film liquide (epaisseur<1mm) afin de permettre une interaction entre le plasma, le liquide et la surface catalytique. Les resultats ont montre que l'utilisation d'une decharge de type DBD etait preferable au Glidarc, thermique, energetique et produisant trop de NOx. Les valeurs d'efficacite respectives etaient de 0,67g.kWh-1 pour la DBD et 0,23g.kWh-1 pour le Glidarc. Les resultats ont egalement montre que le materiau de la contre-electrode/plaque d'ecoulement pouvait influencer l'efficacite du procede. Ainsi dans le cas du laiton, la presence de reactions de corrosion produisant des NO2- reduit l'efficacite de moitie comparee a une plaque d'acier. Le developpement d'un modele CFD 1D a partir des donnees experimentales du procede a ete effectue. Ce modele a permis d'estimer que l'efficacite energetique de production des HO est de 4,4.10-9 molHO.J-1 pour la decharge DBD. Il a egalement permis de montrer que le facteur majoritairement limitant etait la diffusion moleculaire des especes dans le liquide. En effet les reactions chimiques ne dure pas plus de 1µs apres l'impact du streamer et n'ont lieu que dans les premiers 5% d'epaisseur de liquide. Enfin, un depot catalytique de DLC dope a l'argent et realise par rf-PECVD a permis d'ameliorer de pres de 10% l'efficacite maximale du procede.
Utilization of mass media for agricultural information by the dryland farmers

The present study, Utilization of mass media for agricultural information by the dryland farmers was under taken in Umarkhed and Mahagaon Panchayat Samiti of Yavatmal district in Vidarbha region of Maharashtra state. The results found that, the great majority of respondents (90.83%) were utilized television, followed by the majority of respondents (55.83%) were utilized newspaper as mass media for obtaining agricultural information. In case of extent of utilization of mass media, majority of the respondents (75.83%) were fully utilized television as a mass media. Overall (58.33%) of the respondents had medium level of mass media utilization for obtaining agricultural information. In case of suggestions regarding utilization of mass media, great majority (87.50%) of the dryland farmers suggested that, more agricultural TV channels should be available in regional language.
MINING HISTORICAL SOFTWARE TESTING OUTCOMES TO PREDICT FUTURE RESULTS

Software bugs and program defects have significant negative effect on the cost and duration of software development process. Finding such bugs in early stages of the development process will cuts development time and maintenance costs. This investigation presents three different machine learning algorithms: K-Nearest Neighbors (KNN), Random Forest (RF), and Multilayer Perceptron (MLP) to build a new proposed software defect prediction model using different types of software performance metrics. This proposed model was tested on three public datasets obtained from NASA to assess its accuracy and revealed that the KNN was outperforms RF and MLP.
7 The Stratum Corneum and Aging

The father of corneobiology, Albert Kligman [1], wrote in 1979: ‘‘No one dies of old skin! No matter how decrepit the integument becomes after a lifetime of assaults, it continues to perform its primary protective role. But skin problems abound in the aged! ’’ It is now known that dry itchy senile xerotic skin is a problem of faulty epidermal and stratum corneum (SC) maturation together with desquamation. The understanding of the changes in the chemistry and function of important stratum corneum (SC) components in aging and dry skin is a result of the tenacity of a plethora of academic and industrial scientists spanning several decades. These include studies on corneocyte size [2–4]; SC lipid levels, especially ceramides [5–9]; lipid ultrastructure and biophysics [10–12]; natural moisturizing factors (NMF) [13, 14]; SC proteases [15, 16]; corneodesmosomal proteins [11, 17, 18]; and finally corneocyte quality [19, 20]. Ultimately, changes in SC cohesion and desquamatory properties were studied by Ronald Marks [21]. Some of these changes, of course, were predicted in 1964 [22]. Key in SC function and maturation, however, is its hydration [23]. It was not until 1994 that the understanding of the perturbation of water gradients in the SC of subjects with xerotic skin was developed [24] and only in 1995 [25] it was shown that water itself was essential for corneodesmosomal degradation and ultimately desquamation. This chapter gives an overview of the latest understanding of the stratum corneum and aging (> Fig. 7.1).
A Weight Multinet Architecture for Bearing Fault Classification Under Complex Speed Conditions

As a key component in rotating mechanical, fault identification of bearing is a hot topic for machine health condition monitoring. Considering that the corresponding vibration features are seriously influenced by working conditions, the existed classification methods have a high false-positive rate under complex working conditions. Especially, because there is a difference among feature distribution of the measured signals under different speed conditions, the fault identification under uncertain speed conditions is still a big challenge for the fault diagnosis schemes based on expert experience and intelligent fault identification method. Therefore, this study proposes a weight multinet (WMN) architecture, which consists of multiple net units. Different from other traditional networks, the exclusive characteristics of fault information will be mined via a multiclass identification unit, and the vital information related to speed condition will be remained by a weight unit. Then, these fault information with different directivity will be integrated into a fusion unit. Finally, the wavelet packet (WP) energy ratios of vibration signals are extracted and put into this special architecture of neural network with three function units, and the effect of fault classification under unknown speed conditions can be significantly improved. Comparisons of clustering distribution and classification accuracy with other typical methods show the feasibility and effectiveness of the proposed WMN method in the application of fault identification under uncertain speed conditions.
La culture institutionnelle et les droits sociaux : une critique féministe du nouveau management public en contexte autochtone

Depuis plusieurs annees, le gouvernement canadien a entrepris une decentralisation des programmes et des services sociaux destines aux communautes autochtones. Pour certains, c’est une veritable consolidation ascendante de leur droit a l’autodetermination qui se concretise en marge des mecanismes constitutionnels formels. Pourtant, ce processus n’est pas neutre sur le plan institutionnel, puisqu’il coincide avec l’avenement du nouveau management public (NMP). Bien que ce paradigme neoliberal semble octroyer une plus grande autonomie aux pouvoirs locaux, il perpetue plutot un regime genre de l’administration publique, c’est-a-dire organise ou differencie selon le genre, avec des formes limitees de democratie et de representation. A partir d’un cadre d’analyse tire du neo-institutionnalisme, de l’economie politique feministe et du pluralisme juridique, l’auteure soutient que seule une revitalisation des institutions politiques et juridiques autochtones, mises en place a l’exterieur des structures de l’Etat, permettrait aux communautes autochtones de realiser leur droit a l’autodetermination ; en outre, elle pourrait faciliter la participation des femmes au sein de ces structures.
Assessment of selfie addiction among professional medical students of Rama Medical College Hospital and Research Centre, Mandhana, Kanpur

Introduction: Selfie is a self-portrait photograph, typically taken with a digital camera or camera phone held in the hand or supported by a selfie stick. Selfies are often shared on social networking services such as Facebook, Instagram and Twitter. Considering the relationship between personality and selfie-posting behaviors, the study was undertaken to determine the demographics and psycho-social effect of the selfie users, the frequency and nature, reasons and impact of selfies taken. Methodology: It was a cross-sectional observational study conducted among 487 undergraduate medical students of all the batches of Rama Medical College & Research Centre, Mandhana, Kanpur. Out of total 481 enrolled medicos who were selfie users, 100 students were randomly selected by simple randomization method & were interviewed. Data collected and entered in Microsoft Excel sheet & were analyzed using SPSS version 21. Results: Out of total 100 medicos, more (55%) were female & 45% were male. Majority of medicos 43% were interested in head & face selfie shot, out of this majority 72.1% were female & 27.9% were male students. Followed by Body shot 29%, female 69% & male 31% medicos. Minimum selfie shot 13% were with surrounding. There is a significant association between selfie type and gender (Chi-square value is 14.067 and p=.003). Maximum 47 % medicos were involved in average daily 4-6 frequency of taking selfie. Mood is altered depending on number of likes and comments on my selfie. Conclusion: Based on the study it can be conclusively said that age and gender affects the number of selfies one clicks. Be it a behavioral change, peer pressure is a psychological phenomenon in which people do something primarily because other people are doing.
The evolutionary ecology of an insect-bacterial mutualism

Heritable bacterial endosymbionts are responsible for much phenotypic diversity in insects. Mutualists drive large-scale processes such as niche invasion, speciation and mass resistance to natural enemies. However, to persist, mutualists need to be able to transmit with high fidelity from one generation to the next, to be able to express their beneficial phenotypes, and for the benefits they grant the host to outweigh their costs. The effect of ecologically-relevant environmental temperature variations upon transmission and phenotype is a poorly understood area of endosymbiont biology, as is how the symbiont’s cost varies under ecological stress. In this thesis, I examined these parameters for Spiroplasma strain hy1, a defensive mutualist which protects the cosmopolitan, temperate fruit fly Drosophila hydei from attack by a parasitoid wasp. I detected Spiroplasma hy1 in D. hydei individuals from the south of the U.K. The bacterium is at low prevalence compared to hy1 in other localities such as North America and Japan, but its presence in this temperate region conflicts with past studies indicating high sensitivity to low temperatures. I first demonstrate that the vertical transmission of Spiroplasma hy1 is more robust to the cool temperatures typical of temperate breeding seasons than previously considered, with transmission in a ‘permissive passage’ experiment occurring at high fidelity for two generations at a constant 18°C and in an alternating 18/15°C condition. Secondly, I demonstrate that the expression of the defensive phenotype is considerably more sensitive to cool temperatures than transmission. Spiroplasma hy1 protection ceases at 18°C, suggesting that for much of the D. hydei breeding season in areas such as the U.K., hy1 may be selectively neutral in many fly individuals. Finally, I show that hy1 has an unusually low standing cost to its host under starvation stress, contrasting with findings for the related MSRO strain in D. melanogaster. Measures of active cost – the fate of survivors of attack – were unclear. These results indicate that sensitivity to cold temperatures could account for hy1’s low U.K. prevalence. Small amounts of segregational loss could partially counteract selection upon natural enemy resistance, and loss of phenotypic expression at 18°C almost certainly causes hy1 to be neutral at best for parts of early summer and autumn. Future work should investigate the effects of different temperature on costs of symbiont carriage, and whether cool temperatures could push hy1 from mutualism and neutral commensalism to parasitism, as well as investigate how nuclear-mediated anti-wasp protection might interact and compete with hy1-mediated protection.
Building Change Detection in VHR SAR Images via Unsupervised Deep Transcoding

Building change detection (CD), important for its application in urban monitoring, can be performed in near real time by comparing prechange and postchange very-high-spatial-resolution (VHR) synthetic-aperture-radar (SAR) images. However, multitemporal VHR SAR images are complex as they show high spatial correlation, prone to shadows, and show an inhomogeneous signature. Spatial context needs to be taken into account to effectively detect a change in such images. Recently, convolutional-neural-network (CNN)-based transfer learning techniques have shown strong performance for CD in VHR multispectral images. However, its direct use for SAR CD is impeded by the absence of labeled SAR data and, thus, pretrained networks. To overcome this, we exploit the availability of paired unlabeled SAR and optical images to train for the suboptimal task of transcoding SAR images into optical images using a cycle-consistent generative adversarial network (CycleGAN). The CycleGAN consists of two generator networks: one for transcoding SAR images into the optical image domain and the other for projecting optical images into the SAR image domain. After unsupervised training, the generator transcoding SAR images into optical ones is used as a bitemporal deep feature extractor to extract optical-like features from bitemporal SAR images. Thus, deep change vector analysis (DCVA) and fuzzy rules can be applied to identify changed buildings (new/destroyed). We validate our method on two data sets made up of pairs of bitemporal VHR SAR images on the city of L’Aquila (Italy) and Trento (Italy).
Robust Tracking Model Predictive Control With Quadratic Robustness Constraint for Mobile Robots With Incremental Input Constraints

This article proposes a robust model predictive control (MPC) algorithm for the tracking problem of wheeled mobile robots. The robots are subject to bounded disturbances and various practical constraints. Particularly, the incremental input constraint is introduced in the consideration of the safety and comfortability needs in real life. Conditions on the acceleration of the leader robot are derived to guarantee the satisfaction of the incremental input constraint of follower robot. To compensate for the effect of disturbances, a disturbance observer is designed to obtain the estimation of the disturbances, which together with the optimal control input of MPC optimization is contained in the actual control input. Also, a novel quadratic robustness constraint is developed to handle the disturbance estimation error, which allows the designer to balance the initial feasible region and control performance. The proposed algorithm can ensure recursive feasibility, robust constraint satisfaction, and closed-loop stability. Finally, both simulation and experiment results are provided to verify the theoretical properties.
Resource Potential for Sustainable Development of Agricultural Enterprises

The paper is devoted to comprehensive study of the resource potential of agricultural enterprises as one of the factors for sustainable development of the region. Systemic changes in modern society require new approaches to understanding the concept of ‘resource potential’. Informatization of society and digitalization of agriculture imply new attitudes and views on the use of resource support for agricultural enterprises. Based on the analysis of approaches to the concept of ‘resource potential’ available in domestic and foreign science, the authors understand the potential of an agricultural enterprise as a set of material, energy, information and labor resources. The study aims to investigate the structure of the resource potential of agricultural enterprises in postindustrial society and to identify factors that ensure the effectiveness of its use. The methodological basis of the study was the principle of interdisciplinarity and consistency, which allowed us to treat the phenomena studied from different angles, as a whole that consists of interrelated components. The authors consider the resource potential of the region to be a synthetic indicator: each individual resource does not evaluate the enterprise activities. The authors highlight that competent management of the available resources by the enterprise is the key to its successful functioning, and its personnel is the core of the resource potential of any enterprise.
Tradition statt Innovation Die deutsche Presseberichterstattung über die Wahlkampfstrategien der Parteien zur Bundestagswahl 2017

Als Hauptinformationsquelle der Bürger über politisches Geschehen beeinflusst die Medienberichterstattung, insbesondere im Vorfeld von Wahlen, wie Parteien, Kandidaten und auch der von ihnen geführte Wahlkampf in der Bevölkerung wahrgenommen und bewertet werden. Trotz ihres zentralen Stellenwerts für den Wahlkampf der Parteien und möglicher Einflüsse auf den Wahlausgang ist die mediale Berichterstattung über die Wahlkampfstrategien der Parteien bisher kaum empirisch analysiert worden. Hier setzt unsere Studie an. Sie beantwortet die Fragen, wie die überregionale deutsche Qualitätspresse im Vorfeld der Bundestagswahl 2017 über die Wahlkampfstrategien der Parteien berichtete und zusätzlich, wie häufig welche inhaltlichen und kommunikativen Strategien welcher Parteien thematisiert und (wie) bewertet wurden. Unsere Analyse zeigt, dass die Wahlkampfstrategien der Parteien für die Medien ein interessantes und berichtenswertes Wahlkampfthema darstellen: Jeder zweite Wahlkampfartikel thematisierte sie. Ein besonderer Fokus wurde dabei auf die Wahlkampfstrategien der beiden großen Volksparteien CDU/CSU und SPD gelegt - die der kleineren Parteien fanden in der Medienberichterstattung weniger Beachtung. Eine Ausnahme bildete der strategische Wahlkampf von FDP und AfD, die mit ungewöhnlichen bzw. provokanten Kampagnen die mediale Aufmerksamkeit auf sich lenken konnten. Allerdings wurde in der Wahlkampfberichterstattung nur ein sehr begrenztes und überwiegend negatives Bild von den Wahlkampfstrategien der Parteien gezeichnet. Die Berichterstattung konzentrierte sich auf traditionelle kommunikative Strategien, wie Wahlplakate und Wahlkampfauftritte einzelner Politiker; modernere oder gar innovativere Formen fanden hingegen kaum Erwähnung.