Miracle-dz/UniFAR-FTUs huggingface dataset:
Das Ehlers-Danlos-Syndrom mit Schwerpunkt auf dem hypermobilen Typ und dessen Begleiterkrankungen - eine Literaturübersicht

The Ehlers-Danlos Syndrome with Main Focus on the Hypermobile Type and Comorbidities – A Literature Review. The Ehlers-Danlos Syndrome (EDS) encompasses a group of rare, hereditary, multisystemic connective tissue disorders which can affect joints, tendons, muscles, inner organs, skin, and blood vessels. Due to the variety of symptoms and different disease phenotypes, even within the same type of EDS, diagnosis is significantly more challenging. At the moment we differentiate 6 main types and some very rare types, which are distinguished by their genetic causes and symptoms, as described in the Villefranche nosology. The most common type is the hypermobile type, which occurs frequently in combination with other diseases like postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), osteoporosis, polyneuropathy, myopathy, mitral valve regurgitation, bleeding disorders and more. Precisely because of these comorbidities, treatment of EDS is extremely difficult and provides major challenges for a variety of specialists. Therapy is mainly limited to symptomatic treatment consisting of non-invasive physical therapy, pain medication, and surgical intervention as a last resort. The disease severity can range from mild hypermobility to major physical disability. J Miner Stoffwechs Muskuloskelet Erkrank 2015; 22 (Pre-Publishing Online).
Anesthesia for Cesarean Delivery

CHOICE OF ANESTHETIC APPROACH — The anesthetic plan for cesarean delivery should take into account the well-being of two patients: the mother and the fetus. Regional anesthesia is the most common method of anesthesia for delivery because it allows the mother to be awake and immediately interact with her baby. It is also safer for the mother than general anesthesia. In the most recent report of anesthesia-related maternal mortality in the United States (1991-2002 period), the majority of women who died were undergoing a cesarean delivery and there were no deaths associated with vaginal delivery [2]. Maternal mortality associated with general anesthesia was 6.5 per million, while that associated with regional anesthesia was 3.8 per million, a risk ratio of 1.7. Even though overall anestheticrelated maternal mortality continues to decrease, rates for regional anesthesia are rising.
Periodontal Disease and Stroke: An Updated Review of Their Association

1 Department of Oral and Maxillofacial Surgery, Dental School, University of Athens, Greece. Second Department of Neurology, “Attikon” Hospital, School of Medicine, University of Athens, Greece. Department of Neurology, School of Medicine, University of Ioannina, Greece. 4 Department of Neurology, “Eginition” Hospital, School of Medicine, University of Athens, Greece. Vascular Unit, Third Department of Surgery, “Attikon” Hospital, School of Medicine, University of Athens, Greece. 6 Second Department of Neurosurgery, “Attikon” Hospital, School of Medicine, University of Athens, Greece. 7 Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee, USA. 8 International Clinical Research Center, St. Anne’s University Hospital in Brno, Brno, Czech Republic.
On the Generalised Langevin Equation for a Rouse Bead in an Nonequilibrium Bath Link

We present the reduced dynamics of a bead in a Rouse chain which is submerged in a bath containing a driving agent that renders it out-of-equilibrium. We first review the generalized Langevin equation of the middle bead in an equilibrated bath. Thereafter, we introduce two driving forces. Firstly, we add a constant force that is applied to the first bead of the chain. We investigate how the generalized Langevin equation changes due to this perturbation for which the system evolves towards a steady state after some time. Secondly, we consider the case of stochastic active forces which will drive the system to a nonequilibrium state. Including these active forces results in an extra contribution to the second fluctuation-dissipation relation. The form of this active contribution is analysed for the specific case of Gaussian, exponentially correlated active forces. We also discuss the resulting rich dynamics of the middle bead in which various regimes of normal diffusion, subdiffusion and superdiffusion can be present.
The Quality of Dying and Death in Advanced Cancer from the Perspective of Bereaved Caregivers

There were two main research goals of this project: 1) to increase the interpretability of quality of dying and death measures by exploring how respondents generate their evaluations; and 2) to measure the quality of dying and death in advanced cancer patients and consider the influence of specialized palliative care and place of death on this outcome. To understand how respondents evaluate dying and death, 22 caregivers of deceased cancer patients were asked to take part in a cognitive interview protocol after formulating the 31 quality ratings that contribute to the total Quality of Dying and Death (QODD) questionnaire score. Qualitative content analysis was applied to transcribed interviews. Results suggested that evaluations were based on multiple different perspectives and standards of comparison. Findings highlighted that the family should be the targeted unit of end-of-life care and attention should be paid to helping families anticipate and prepare for the realities of the dying process. To measure the quality of dying and death of patients with cancer and examine its relationship to receipt of palliative care and place of death, 402 caregivers of deceased cancer patients were interviewed with the QODD. Overall quality of dying and death was rated in the “neither good nor bad” to “almost perfect” range by 99.8% of caregivers. The lowest QODD subscale scores
THE ROLE OF BRAND AWARENESS MEDIATES THE RELATIONSHIP CREDIBILITY BETWEEN ENDORSER AND ONLINE PURCHASE INTENTION THROUGH ONLINE SHOPPING SITE BUKALAPAK.COM

This study aims to find out how the role of brand awareness mediates the relationship of endorser credibility with online purchase intention by using the online shopping site Bukalapak.com. The location of research was in Denpasar City with the number of respondents 110 people. Data analysis techniques used are Path Analysis. The results showed, brand awareness has positive and significant effect on purchase intention. Celebrity endorsers has positive and significant effect on brand awareness. Celebrity endorsers has positive and significant effect on purchase intention. Brand awareness able to mediate the influence of celebrity endorser on purchase potential Bukalapak.com.
The Post-IPO Performance in the PRC

The long-run underperformance of IPOs (Initial Public Offerings) is one of the three “New Issues Puzzles” It indicates that if investors buy IPOs and hold for more than three years they will get negative abnormal returns It is necessary to examine the long-run performance of IPOs in China because it benefits how to enhance the efficiency of IPOs market and provides insight of emerging market This paper empirically examines the performance for three years after listing of 76 Shanghai Stock Exchange IPOs form 2002 to 2007, the matched company as the benchmark, the matched company comes from the same industry and similar circulated stock value with listed companies. First it computes the long-run excess returns of the IPOs with types of models. Then it examines whether the underperformance has statistical significance or not. After that, it analyzes the relationship between the variables and long-run performance of IPOs. Research documents that the IPOs significantly underperformed the matched companies. The cumulative abnormal returns over the three years listing are -0.18446. The buy and hold abnormal returns over three years after listing are-0.01284. At last, using the cross-sectional analysis to analyze the factors that affect the long-run performance of IPOs, the regression result shows that EPS is the basic reason; the intrinsic value, issue characteristics and the investors’ sentiment (overoptimistic) are the main reason for long-run performance of IPOs. This paper analyzes the reason of this phenomenon, then from the reason puts forward relevant suggestions: firstly, improving the information disclosure; secondly, evaluating the rational investors; thirdly, strengthening market supervision.
Discrete Sizing of Steel Frames Using Adaptive Dimensional Search Algorithm

Adaptive dimensional search (ADS) algorithm is a recently proposed metaheuristic optimization technique for discrete structural optimization problems. In this study, discrete sizing optimization problem of steel frames is tackled using the ADS algorithm. An important feature of the algorithm is that it does not use any metaphor as an underlying principle for its implementation. Instead, the algorithm employs an efficient performance-oriented methodology at each iteration for convergence to the optimum or a near optimum solution. The performance of the ADS is investigated through optimum design of five real-size steel frame structures and the results are compared versus several contemporary metaheuristic techniques. The comparison of the obtained numerical results with those of available designs in the literature reveals the reliability and efficiency of the ADS in optimum design of steel frames.
ROLE OF INDAPAMIDE ON HYPERTENSIVE LEFT VENTRICULAR HYPERTROPHY

Left ventricular hypertrophy (LVH) is a sequelae of sustained prolonged systemic hypertension Initially it is a compensatory mechanism but later on the left ventricular hypertrophy carries the risk of arrhythmias, congestive cardiac failure, angina, systolic as well as diastolic dysfunction, greater intensity and risk of myocardial infarction and cardiac rupture. The Framingham Heart Study and other studies have shown LVH as an independent risk factor for cardiovascular morbidity and mortality. Some classes of drug cause regression of LVH e.g. ACE inihibitor, AT1 receptor blockers, calcium channel blockers, B blockers and methyldopa. The effect of diuretics on regression are equivocal. we gave indapamide 2.5mg to 7 pts with echocardiographic evidence of LVH and found that LVID (mm) (mean + SEM) decreased from 50.7+ 1.2 to 50.20 + 1.70, IVST (mean + SEM) decreased from 14.10 + 0.4 to 11.9 + 0.30, PWT (mean + SEM) decreased from 13.0 + 0.3 to 11.2 + 0.2 and LVMI (mean + SEM) decreased from 176.42 + 6.13 to 145.25 + 6.04g/m 2
Caracterización del régimen bioclimático medio del área metropolitana de Madrid mediante la aplicación de la temperatura fisiológica (PET)

En este trabajo hemos caracterizado el bioclima del area madrilena a partir de los datos diarios del observatorio del aeropuerto de Barajas. Hemos obtenido la temperatura fisiologica (PET), maxima y minima diaria, durante el periodo 1985-2004 y los diferentes umbrales de confort, siguiendo la metodologia propuesta por la comision 6 de la ISB. Se observa que, a partir de 2000, han aumentado los dias extremadamente calidos y se han adelantado estas situaciones a los meses de mayo y junio, descendiendo significativamente en Septiembre.
Addition of Simvastatin to Carvedilol and Endoscopic Variceal Ligation improves rebleeding and survival in patients with Child-Pugh A and B class but not in Child Pugh C class

Background: Even with current standard treatment after variceal bleeding which includes combination of nonselective b-blockers and repeated endoscopic variceal ligation, the risk of rebleeding and mortality are high. Statins exhibit an antifi brotic effect and improves HVPG. We evaluated whether addition of simvastatin to carvedilol plus EVL therapy reduces variceal rebleeds or death in patients with cirrhosis.
COMMUNITY SUPPORTED AGRICULTURE (CSA) AS A FORM OF SUSTAINABLE CONSUMPTION

The article describes the activities and specificity of so-called CSA groups (Community Supported Agriculture) as one of the forms of the observable trend related to the formation of different types of informal, mutual social initiatives. Certainly such activities can be categorized as sustainable consumption. The article presents the results of research conducted on CSA groups operating in Poland. This study aims is to contribute to the discussion by combining data from basic research with a comparative analysis. The research shows that the various CSA-projects differ a lot from each other and that there is a variety of approaches within the CSA-movement.
THE INFLUENCE OF INSTITUTIONAL MEASURES AND TECHNOLOGICAL PROFICIENCY ON UNIVERSITY TEACHING THROUGH DIGITAL PLATFORMS

The objective of this study is to empirically test the theoretical model that explains the influence of primary and secondary factors on the integration of digital platforms in university teaching. A sample of 495 teachers from universities in Andalusia completed an online questionnaire that analysed the functions of usage, the digital materials used, the didactic and technological proficiency of the teaching staff, the support measures adopted by the institutions and the effect on teaching of platform use. Prior factor analysis and the application of the Amos program enabled us to develop a structural equation model to corroborate the indirect influence of the support measures and institutional recognition on teachers in their use of the platforms, and the direct influence of the teachers’ technological proficiency. Resumen Este estudio tiene como objetivo poner a prueba empíricamente el modelo teórico que explica la influencia de los factores de primer y segundo orden sobre la integración de las plataformas digitales en la docencia universitaria. Para ello, sobre una muestra de 495 profesores universitarios andaluces, se aplica un cuestionario online que analiza las funciones de uso, materiales digitales utilizados, competencia didáctica y tecnológica del profesorado, medidas de impulso institucionales, y efectos didácticos del uso. El análisis factorial previo y la aplicación del programa Amos permite la elaboración un modelo de ecuación estructural que corrobora la influencia indirecta de las medidas de apoyo y el reconocimiento institucional sobre los efectos didácticos del uso de plataformas, así como la influencia directa de la competencia tecnológica del profesorado.
Hydraulic and Diffusive Behavior of a Compacted Cemented Soil

The study evaluated, through a series of permeability and diffusion tests, the hydraulic and the attenuation behavior of a compacted clayey soil, with and without the addition of Portland cement (0 to 2%). To evaluate the diffusive response, the specimens were subjected to a vertical static load (100 to 500 kPa), simulating the action of a waste mass, and to an acidic solution enriched with toxic metals Pb or Cd, prepared with pH varying from 1 to 6. The reactive behavior analysis indicated that retention by adsorption increased with the increase of pH, but was not affected by the applied static load. The combination of higher cement contents with higher pH caused precipitation to prevail over adsorption reactions.
Plasma Treatment in-Water Processes of Sugarcane Bagasse

Sugarcane (Saccharum officinarum L.) is an indispensable plant, representing most of the cultivated plants throughout the world. Sugarcane is processed to produce crystalline sugar and bioethanol. The treatment process produces sugarcane bagasse waste. Sugarcane bagasse waste can be utilized through some treatment. In this study, Plasma Treatment (PT) in-Water treatment was applied to sugarcane bagasse to investigated the glucose concentrates and by-products. PT in-water energy input parameters were 320, 340, and 400 W with an irradiation time of 1, 2.5 and 5 minutes. Sugarcane bagasse after treatment and by-products were tested using the Nelson Somogyi method to determine glucose percentage and characterized using Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscope (SEM) and Image-J software. The results showed that the percentage of glucose in sugarcane bagasse decreased from 0.028% to 0.00023% at 400 W energy input, the irradiation time of 5 minutes. the by-product resulted in cellulose nanoparticles which had an average diameter from 276.14 to 105.78 nm at each energy input variation.
ePubWU Institutional Repository

When committing to quantitative political science, a researcher has a wealth of methods to choose from. In this paper we compare the established method of analyzing roll call data using W-NOMINATE scores to a data-driven supervised machine learning method: Regression and Decision Trees (RDTs). To do this, we defined two scenarios, one pertaining to an analytical goal, the other being aimed at predicting unknown voting behavior. The suitability of both methods is measured in the dimensions of consistency, tolerance towards misspecification, prediction quality and overall variability. We find that RDTs are at least as suitable as the established method, at lower computational expense and are more forgiving with respect to misspecification.
SERIES 0LUNG INFECTION AND LUNG IMMUNITY0 Edited by M. Spiteri and L.P. Nicod Number 6 in this Series

Mechanisms and markers of airway inflammation in cystic fibrosis. V. De Rose. #ERS Journals Ltd 2002. ABSTRACT: Airway inflammation is now recognized as a major factor in the pathogenesis of lung disease in cystic fibrosis (CF). Its most characteristic feature is a marked and persistent influx into the airways of neutrophils, which damage the lung by releasing noxious mediators, such as reactive oxygen species and proteolytic enzymes. Recent studies suggest that inflammation occurs very early and may even happen in the absence of infection. Furthermore, links between CF transmembrane conductance regulator dysfunction and both infection and inflammation are postulated; dysregulation of cytokine production and abnormal epithelial host defences have been regarded as causes of sustained inflammation. Bronchoalveolar lavage and the evaluation of neutrophils and inflammatory media- tors provide the most accurate picture of airway inflammation. Routine bronchoscopy with bronchoalveolar lavage, however, is unpleasant for the patient and usually is of no immediate benefit to the management of individual cases. Therefore, surrogate markers collected by noninvasive procedures would be of great assistance in the follow-up of cystic fibrosis patients. Several markers have been evaluated in the sputum, serum and urine of cystic fibrosis patients and related to the degree of airway inflammation. Long-term studies are needed to confirm their potential clinical utility and specificity, and to determine which can be used clinically to monitor disease outcome and efficacy of treatment. Eur Respir J 2002; 19: 333-340.
The Cr(VI) Bioremediation Potential of Chlamydomonas Debaryana

Chromium (Cr) is an essential industrial component and has many applications in industrial manufacturing. Anthropogenic activities can lead to the release of hexavalent chromium [Cr(VI)] as well as trivalent chromium [Cr(III)]. Cr(VI) is 1,000 times more toxic than Cr(III), and very detrimental to most organisms even at low concentrations. Chlamydomonas debaryana, a freshwater algae, appeared to be Cr(VI) resistant and was able to survive in Cr(VI) concentrations of up to 80 mg/L for an extended period in packed aquifer media columns. This micro-green algae strain was isolated alongside Cr(VI) reducing bacteria (CRB) at a Cr(VI) contaminated site in South Africa. In this study, the growth response of C. debaryana in the presence of Cr(VI) was compared to that of Chlamydomonas reinhardtii, to assess the Cr(VI) tolerance of C. debaryana. At 50 mg/L Cr(VI) concentration the maximum chlorophyll a increase was 25.3 % for C. debaryana and 34.2 % for C. reinhardtii. However, after 3.5 d the chlorophyll a content decreased only 38.1 % for C. debaryana compared to a 100 % decrease for C. reinhardtii. Indicating that C. debaryana is only slightly more resistant than C. reinhardtii. Zero Cr(VI) removal was observed with the algae: C. debaryana could not reduce Cr(VI) to Cr(III) or adsorb Cr(VI) anions from the solution. C. debaryana as well as C. reinhardtii, algae cells are inhibited when directly exposed to Cr(VI) in continuously mixed batch reactors. C. debaryana might be better suited to use in cooperation with CRB for Cr(VI) treatment in a biofilm reactor. This research can lead to an improved treatment set up for Cr(VI) pollution that requires fewer chemical and energy inputs and produces less secondary waste.
‘WE’ AND ‘OTHERS’: STEREOTYPE ATTITUDES OF STUDENTS IN SERBIA*

The paper analyzes the data obtained in the course of two empirical studies of Serbian students’ attitudes. The first research of autoand hetero-stereotypes was conducted in 2012 on the quota sample of 363 students of Pristina University with temporary Head Office in Kosovska Mitrovica. The results regarding the ethnic stereotypes of Russians were analyzed and compared with the data from the research conducted in the same year on the sample of 603 students of the state universities of the Republic of Serbia. The results indicated that extremely positive auto-stereotypes dominated among the students as well as extremely positive stereotypes of Russians — not only among the students that study in Kosovo and Metohija, but also in other high-school institutions in Serbia. Moreover, moderately negative stereotypes of Montenegrins were revealed, as well as those of Germans and Americans, with significant differences in the disposition of attributes’ frequencies that, however, do not form the core of the stereotypes.
Color Based Segmentation of White Blood Cells in Blood Photomicrographs Using Image Quantization

Generally for various diseases blood is used as an indicator. It is composed of three types of cells; Red blood Cells (RBC), White Blood Cells (WBC) and Platelets. Different types of white blood cells or leukocytes are counted in a sample blood smear and give necessary information about various hematological diseases. Evaluating a blood smear for WBC’s with the help of digital image processing is faster, easier and has contributed strongly in Computer Aided Diagnosis (CAD). In this work, we have focused on the segmentation of white blood cells in blood smear photomicrographs and proposed a novel technique for segmentation which can exploit color, size and shape features of different types of objects present in a blood smear photomicrographs.
Hierarchical deep neural networks for MeSH subjectprediction

Extreme Mutli-Label Text classification (XMTC) problems attempt to assign a few relevant labels to text from an extremely large label-space. XMTC label spaces generally follow a power law distribution, resulting in data sparsity issues for tail labels and aggressive prediction of head labels. Deep learning methods for tackling such large scale problems have recently gained attention and have reached state-of-the-art performance. Notably, XML-CNN is a deep learning architecture that was tailored specifically towards XMTC problems. Assigning relevant labels to medical journals in the Medline dataset is an XMTC problem with a highly skewed label-space and highly arcane terms. This project explored modifications to XML-CNN by implementing a hierarchical XML-CNN architecture to leverage the inter-label relationships for training and classification. An automated hierarchy generated by Hierarchical Agglomerative Clustering and the expert-curated MeSH hierarchy for medline were used to evaluate prediction performance. Borrowing from the concept of multi-task learning, the hierarchies were used to modify the XML-CNN architecture to function as a single model using hard parameter sharing with separate loss functions for each level of the hierarchy. The experiments were focused on testing the effect of the hierarchical approach, the effect of an automatically generated hierarchy and that of a manually curated hierarchy. The use of hierarchies were found to be less suited for medline label prediction than the original XML-CNN model. However, the performance of the hierarchical models were comparable to XML-CNN and is sufficiently high that the hierarchical models cannot be considered ineffective for subject prediction tasks.