Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental and theoretical approach to comparative nanoparticle and small molecule intracellular import, trafficking, and export

Central to understanding how nanoscale objects interact with living matter is the need for reproducible and verifiable data that can be interpreted with confidence. Likely this will be the basis of durable advances in nanomedicine and nanosafety. To develop these fields, there is also considerable interest in advancing the first generation of theoretical models of nanoparticle uptake into cells, and nanoparticle biodistribution in general. Here we present an uptake study comparing the outcomes for free molecular dye and nanoparticles labeled with the same dye. A simple flux-based approach is presented to model nanoparticle uptake. We find that the intracellular nanoparticle concentration grows linearly in time, and that the uptake is essentially irreversible, with the particles accumulating in lysosomes. A wide range of practical challenges, from labile dye release, to nanoparticle aggregation and the need to account for cell division, are addressed to ensure these studies yield meaningful kinetic information.
Efficacy of phytase on the humoral immunity of broilers fed nutritionally marginal diets supplemented with citric acid and multi carbohydrase enzymes

The aim of this study was to investigate the effects of using citric acid and multi carbohydrase enzymes on phytase efficacy on the humoral immunity of broiler chickens fed diets with nutritionally marginal calcium and nonphytate phosphorous (Ca-nPP). A total of 320 one-day-old male broiler chickens were randomly assigned to 8 treatment groups, with 4 replicates per treatment and 10 chicks per replicate in a completely randomized design. Eight dietary treatments containing, T1: adequate level of Ca-nPP as positive control diet (CTL+), T2: reduced levels of Ca-nPP as negative control (CTL−), T3: negative control diet + 1000 unit/kg phytase, T4: negative control diet + 1 % citric acid, T5: negative control diet + multi carbohydrase enzymes, T6: negative control diet + 1000 unit/kg phytase and 1 % citric acid, T7: negative control diet + 1000 unit/kg phytase and multi carbohydrase enzymes and T8: negative control diet + 1000 unit/kg phytase +1 % citric acid + multi carbohydrase enzymes. Blood samples were taken from each bird and the titers of maternal antibody against Newcastle disease virus (NDV) and avian influenza virus (AIV) were measured by haemagglutination-inhibition (HI) test. Addition of phytase to the diet increased significantly (P<0.05) antibody production against NDV and AVI as compared to birds fed CTL− diet in T2. In conclusion, the inclusion of citric acid and multi carbohydrase enzymes to the diet improved the effectiveness of phytase on antibody production against NDV and AVI in broiler chickens.
For the Journal “Electrical and Electronic Engineering”, SAPUB Design of PCB for Power LEDs – Thermal Investigations

Investigations deal with development of cost effective thermal management fo r power LEDs. The technique involves usage of FR4 based PCBs which cost less, but have greater thermal resistance than metal core printed circuit boards (MCPCB). The use of copper p ins underneath LED thermal pad is a method to dissipate heat through an FR4 PCB into an appropriate heat sink. Temperature reg imes of operation of power XLamps LEDs mounted on MCPCBs and on the PCBs with copper p in are experimentally tested at various ambient conditions (air temperatures fro m 20℃ to 45℃) and different current values through LEDs - up to 600 mA. Infrared thermography for evaluation of temperature distribution on LEDs and heat sink is used. Thermal management investigations show that the developed design of FR4 PCB is successful and possess a lot of advantages.
Removing the 'Fuel of Interest' from the 'Fire of Genius': Law and the Employee-Inventor, 1830-1930

The workmen in each of these trades have had their knowledge handed down to them by word of mouth . The ingenuity and experience of each generation . have without doubt handed over better methods to the next. This mass of rule-of-thumb or traditional knowledge may be said to be the principal asset or possession of every tradesman. [The] foremen and superintendents know, better than any one
An Electromagnetic Articulography study of resyllabification ofrhotic consonants in English.

Recent instrumental work has focused on finding phonetic correlates of intervocalic consonants’ syllabic affiliation. The importance of lexical stress as a determining factor word internally has either been acknowledged [1], or suggested [2]. There is much work in word internal contexts, but limited work across word boundaries. I examined word final intervocalic [] in non-rhotic English speech, with Electro-magnetic Articulography (EMA) using car out and peer out for stimuli, varying the emphatic stress environment. For two speakers, the lingual articulators moved more rapidly in the transition from word final [] to the following vowel when the word following was stressed. A Scottish rhotic speaker showed the same effect. The higher velocity suggests the consonant is more likely to be parsed as a syllable onset. I argue emphatic stress increases tension which accounts for the low velocity observed in tokens where the first word was stressed and that the stiffness parameter (k) of Articulatory Phonology is related to bio-mechanical stiffness.
A lattice dynamical study of the aragonite and post-aragonite phases of calcium carbonate rock

Abstract A recent force field model is used in this paper to analyze, with a nano-scale simulation, the structural and the vibrational properties of a rock system under the application of various high pressures. Our results show that this model reproduces accurately the equilibrium structural properties for calcite, gives comparable results for aragonite with the observed data, and predicts the structural, elastic and vibrational properties of the post-aragonite phase. In addition, we show that the transition from the aragonite to the post-aragonite phase appears at a transition pressure of 35.2 GPa. The longitudinal wave velocity increases rapidly by a factor of 1.71. In contrast the shear wave velocity increases very slowly up to the transition pressure, and thereafter increases rapidly, changing by 45% to 80 GPa. In addition, our calculations for the vibrational properties show that with the new potential model presented here, we observe a softening mode in the Γ-F direction. The phonon frequencies of the post-aragonite phase show more modes than for calcite and aragonite.
SCREENING FOR STAPHYLOKINASE PRODUCING STAPHYLOCOCCUS SPP. FROM DIFFERENT ENVIRONMENTAL SAMPLES

Staphylokinase (SAK) is a bacterial kinase produced by certain strains of Staphylococcus spp. It is a 15.5 kDa, consisting of 136 amino acids single chain protein, which activates plasminogen to form plasmin and digest fibrin clots. Staphylokinase (SAK) is a promising thrombolytic agent for the treatment of myocardial infarction. The present research work was carried out to screen the staphylokinase producing Staphylococcus spp. from different samples collected (milk, water and sewage) in and around Vellore district, Tamil Nadu, India. Out of 12 isolates, 4 organisms were producing staphylokinase effectively. The main focus of this work is to isolate and characterise potent producers of staphylokinase producing Staphylococcus spp. from various environmental samples involving non-pathogenic Staphylococcus spp. while the earlier isolation was done using pathogenic samples.
A Clustering Based Feature Selection Approach to Detect Spam in Social Networks

In recent years, online social networks (OSNs) have been expanded with a lot of facilities and many users and enthusiasts have joined to OSNs. On the other hand, the proportion of low-value content such as spam is rapidly growing and releasing in the OSNs. Sometimes the spam advertising purposes, commercial purposes or spreading lies in the different mailing lists are placed and shipped in bulk to send for social network users. Spams not only damage the interests of users, usage time and bandwidth, but also are a threat to productivity, reliability and security of the network. In this paper, we present an online spam filtering system that can be deployed as a component of the OSN platform to inspect message generated by users in real time. Our filtering method is working on the basis of different features such as like, replay, hash tag, followers, and the existing URLs in the posts of Facebook social network. We employ three clustering algorithms for this purpose and we also use naive Bayes and decision tree to detect spam from non-spam. We evaluate the system using 2000 wall posts collected from Facebook.
USE OF A LIGHT UAV AND PHOTOGRAMMETRIC TECHNIQUES TO STUDY THE EVOLUTION OF A LANDSLIDE IN JAÉN (SOUTHERN SPAIN)

This paper presents a methodology for slope instability monitoring using photogrammetric techniques with very high resolution images from an unmanned aerial vehicle (UAV). An unstable area located in La Guardia (Jaen, Southern Spain), where an active mud flow has been identified, was surveyed between 2012 and 2014 by means of four UAV flights. These surveys were also compared with those data from a previous conventional aerial photogrammetric and LiDAR survey. The UAV was an octocopter equipped with GPS, inertial units and a mirrorless interchangeable-lens camera. The flight height was 90 m, which allowed covering an area of about 250 x 100 m with a ground pixel size of 2.5 cm. The orientation of the UAV flights were carried out by means of ground control points measured with GPS, but the previous aerial photogrammetric/LiDAR flight was oriented by means of direct georeferencing with in flight positioning and inertial data, although some common ground control points were used to adjust all flights in the same reference system. The DSMs of all surveys were obtained by automatic image correlation and then the differential models were calculated, allowing estimate changes in the surface. At the same time, orthophotos were obtained so horizontal and vertical displacements between relevant points were registered. Significant displacements were observed between some campaigns (some centimeters on the vertical and meters on the horizontal). Finally, we have analyzed the relation of displacements to rainfalls in recent years in the area, finding a significant temporal correlation between the two variables.
Inbreeding and Inbreeding Depression in Iranian Moghani Sheep Breed

The objective of this study was to determine the inbreeding depression on growth traits in Moghani sheep. Pedigree information of 8836 animals collected during the years of 1987 to 2006 by Moghani Breed Center in Jafar Abad Moghan, were used for analysis. The base population year was 1988. Analysis of the records was performed by ASReml software. Inbreeding depression was estimated as the regression of performance on the individual inbreeding coefficients via fitting an animal model. The mean inbreeding for all animals, females and males, were 0.500, 0.515 and 0.484 %, respectively. Totally, 24.22 % of all the animals were inbred. The mean of inbreeding for inbreed animals was 2.062 %. The rate of increased inbreeding per year for all animals was 0.05%. The inbreeding depression for body weight traits at birth, 3, 6, 9 and 12 months of age was , respectively, - 0.007, - 0.291, - 0.026, -0.018 and -0.041 kg, per 1% increase in individual coefficient.
Farmer: Agrochemical Use and Associated Risk Factors in Fadan Daji District of Kaura LGA, Kaduna State, Nigeria

Background: Occupational poisoning via the use of agrochemicals is common in developing countries. This is because grass-root farmers, who are the majority, are poor, illiterate and are undertrained on ethics surrounding its use. This is a cross sectional descriptive study carried out in Fadan-Daji (FD) district of Kagoro Chiefdom, Kaura LGA, Kaduna state, Nigeria. Methods: Three villages - Kodwak, Uzha-Tuyit and Zankam were randomly selected in the district. A sample size of 250 farmers was obtained using a p-value of 82%, while the selected farmers completed structured questionnaires. Results: Physical, chemical, biological, mechanical and psychosocial events occurred at the same time in the FD Farming community. Thus, clients present with multiple finding or symptoms. In this study most farmers experienced chest pain/tightness, cough, dizziness, reddening of the eyes; sneezing and rheum more often following the use on their farms. This study further revealed that farmers in the studied communities (31.6%) resorted to self-medication ranging from analgesics, to over the counter antihistamines, whilst 23.6% reported that they ingest milk as antidote. 32.4% did nothing about it while only 12.4% of the respondents visited a health facility. 54.4% of FD farmers used no form of personal protective devices (PPDs). Conclusion: Our findings revealed that the root problem faced with the FD like the average farmer of the developing world is lack of relevant education in terms of ethical use and disposal of agrochemicals which has made a significant number of FD farmers more susceptible to the agrochemical side effects resulting from its use. Such a community located in the heart of Nigeria also being a food basket needs prompt attention in terms of improved western/farmer education and health facilities.
Planet, People, Prosperity in Finnish and Dutch Mass Tour Operators Customer Communications

Author Ingrit Felkers Degree programme Degree Programme in Tourism Management Report/thesis title Planet, People, Prosperity in Finnish and Dutch Mass Tour Operators Customer Communications Number of pa ges and appendix pages 61 + 3 Mass tour operators, host holiday destinations and tourists have as common interest the preservation of attractive natural surroundings, positive encounters between visitors and the host community as well as welfare for business and society. Sustainable tourism has been presented the past two decades as new concept idea for arranging tourism services and products. The Tour Operators Initiative for Sustainable Tourism Development supported tour operators in the process toward better sustainability in business operations by sharing knowledge and good practices in a pilot project from 2000 to 2014. Mass tour operators’ sustainable operations reflected in their site communications are interdependent with both the demand side and destinations host suppliers. Dutch and Finnish tourists are introduced with their attitudes and interests in tourism for a better understanding of the communication content of mass tour operators in Finland and the Netherlands. Coastal Mediterranean Europe destinations in Spain and Greece are presented with the current situation and sustainability developments as Planet, People and Prosperity communications are only possible with a certain degree of environmental, social and economic practices at the destination. The thesis studied the integration of sustainability at the Planet (environment), People (sociocultural) and Prosperity (economic) levels in communications by Finnish and Dutch mass tour operators. The site customer communications of the Dutch mass tour operators TUI (ARKE), Neckermann Reizen and Sudtours Vliegvakanties and Finnish tour operators Finnmatkat, Tjareborg and Aurinkomatkat are explored in a comparative research. The purpose was to study the emphasis balance of the 3P concept in Finland and the Netherlands. The study focused on site communications in customer relations. The communicative elements informing, coaching and sharing as well as sales text have been used in the research for a more holistic insight. Dutch and Finnish tour operators showed equal good consideration in sustainability communications with clear emphasis on the Planet level. The result can be explained by the (multi) national tour operating groups and Initiatives in the tourism industry enhancing exchange of knowledge and good sustainability practices. The communicative element sales needs improvements for being clear Planet, People and Prosperity level communications as text focuses much on the holiday experience in senses with sustainability aspects for own interpretation and understanding. Finnish and Dutch mass tour operators show commitment to the 3P sustainability concept and have taken their intermediary role seriously. Further integration progress depends much of major concerns at the 3P levels: climate change, conflicts, EU crisis.
3D DIRECTIONAL MATHEMATICAL MORPHOLOGY FOR ANALYSIS OF FIBER ORIENTATIONS

In this paper we present algorithms for measuring local characteristics of random fiber systems. The calculation of the local directions and radii is based on directional distance transforms and evaluation of the inertia moments and axes of the resulting extremities of the centralized, directed chords. The method provides continuous results while minimizing the runtime by using few sampled directions. Furthermore several steps of improvement for the computation of orientation and radius information are presented. The algorithms are evaluated using synthetic data and applied to images of realmicrostructures obtained by computer tomography.
Energy Neutral Sensor System With Micro-scale Photovoltaic and Thermoelectric Energy Harvesting

Minimizing power conversion losses is critical for energy neutral operation of micro-scale energy harvested sensor nodes. These small form-factor sensor nodes rely on miniature harvesters with low output voltages that must be boosted with large conversion ratios to recharge batteries or super-capacitors. Selective Direct Operation (SDO), a technique to selectively avoid power conversion and thereby eliminate conversion loss in energy harvested systems has been demonstrated as an effective technique for light harvesters. This paper extends SDO to thermoelectric generators (TEGs). SDO exploits the ultra-low circuit functional voltages, enabling sensor systems to effectively harvest energy from cm-scale TEGs which output few 10’s of mW but at low output voltages (100’s of mV). PV cell construction from prior-work, TEG characterization and field measurements are presented in this paper to demonstrate the effectiveness of SDO and co-designing energy harvesters, power conversion circuits and digital sub-systems.
What to Read in the Morning? A Niche Analysis of Free Daily Papers and Paid Papers in Korea

Since Metro was first launched in Seoul, Korea in May 2002, multiple local titles followed, and free daily papers (FDPs) have been building up their own niches through competition with paid papers for readership and sales as well as expanding their competitive power. In addition, despite their short history, FDPs influence readers' usage behavior and create changes in the morning paid paper market through competition. How do readers perceive FDPs in terms of need satisfaction? This study analyzed the competition among three types of papers (paid newspapers, paid sports papers, and FDPs) in Korea through using niche theory and a uses and gratifications perspective. The findings revealed that FDPs are generally better than sports papers in terms of niche breadth, overlap, and competitive superiority in gratification factors. There has also been competitive displacement between FDPs and sports papers–paid newspapers in consumer usage. In conclusion, FDPs have been successfully established to threaten sports papers and paid newspapers in the morning paper market.
Uji Efektivitas Beras Herbal Forte terhadap Penurunan Kadar Glukosa Darah Pasien Diabetes Melitus Tipe 2 (Study of the Herbal Rice Forte Effectiveness on Decreasing Blood Glucose of Diabetes Mellitus Type 2 Patient)

e-Jurnal Pustaka Kesehatan, vol. 6 (no. 1), Januari 2018 85 Osteoartritis adalah suatu kelainan sendi kronis dimana terjadi proses pelemahan dan disintegrasi dari tulang rawan sendi yang disertai dengan pertumbuhan tulang dan tulang rawan baru pada sendi. Salah satu mediator inflamasi yang ikut berperan penting dalam progresifitas osteoarthritis adalah TNF-α. Minyak ikan lemuru yang memiliki kandungan EPA dan DHA dapat berfungsi sebagai anti-inflamasi. Tujuan penelitian ini adalah membuktikan adanya pengaruh minyak ikan lemuru (Sardinella longiceps) terhadap penurunan ekspresi TNF-α pada kartilago yang diinduksi Complete Freunds Adjuvant. Jenis penelitian yang digunakan adalah true experimental dengan rancangan penelitian the randomized post test only control group design. Kelompok penilitian terbagi menjadi 2 kelompok yaitu kelompok kontrol negatif (K-) dan kelompok perlakuan (P), masing-masing kelompok terbagi menjadi 3 sub kelompok berdasarkan lama pemberian minyak ikan lemuru yaitu 7, 14 dan 21 hari. Data ekspresi TNF-α didapat dari skor histologi hasil pengamatan imunohistokimia kartilago sendi tibiofemoral pada perbesaran 400x dalam lima lapang pandang. Hasil penelitian didapatkan ekspresi TNF-α pada kelompok perlakuan lebih rendah dari pada kelompok kontrol negatif dan Uji One Way Anova menunjukkan perbedaan secara signifikan antarkelompok (p = 0,000). Sehingga, dapat disimpulkan bahwa minyak ikan lemuru (Sardinella longiceps) dapat menurunkan ekspresi TNF-α.
An approach to beacons detection for a mobile robot using a neural network model

In this paper we propose a neuro-mimetic technique relating to the detection of beacons in mobile robotics. The objective is to bring a robot moving in an unspecified environment to acquire attributes for recognition. We develop a practical approach for the segmentation of images of objects of a scene and evaluate the performances in real time of them. The neuronal classifier used is a window of a network MLP (9-6-3-1) using the algorithm of retro-propagation of the gradient, where the distributed central pixel uses information in level of gray. The originality of the work lies in the use of the association of an enhanced neural network configuration and Standard Hough Transform. The results obtained with a momentum of 0.3 and one coefficient of training equal to 0.02 shows that our system is robust with an extremely appreciable computing time.
DIETARY MANIPULATION OF THE CALCIUM CONTENT OF FEED CRICKETS

Insects used in zoo feeding programs are poor sources of calcium (Ca) and have inverse calcium : phosphorus (Ca:P) ratios. An experiment was conducted to determine if feeding diets high in dietary Ca to adult crickets would cause an increase in whole-body Ca content. Experimental diets were formulated to contain 2, 4, 6, 8, 10, and 12% Ca and were provided to the crickets for 12, 24, 48, 72, 96, and 120 hr. Crickets were analyzed for dry matter, Ca, and phosphorus. Dietary treatment and duration of treatment were found to have significant effects on Ca content and Ca:P ratio of crickets, but not on P content. The Ca content and Ca:P ratio of crickets increased during the initial period of feeding, but after 48 hr these mineral levels remained stable. Calcium content and Ca:P ratio of crickets were a function of dietary Ca, reaching maximal values of 1.4% and 1.7:1, respectively, when diets containing 12% Ca were fed. Radiographs revealed radiopaque material in the gastrointestinal tracts (GIT) of most crickets fed diets high in calcium (8, 10, or 12% Ca) but not in the GIT of crickets fed diets low in calcium. It is concluded that in order to obtain crickets with a Ca:P ratio of 1:1 or higher it is necessary to feed diets containing at least 8% Ca. Other factors