Miracle-dz/UniFAR-FTUs huggingface dataset:
New Constraints on Classical de Sitter: Flirting with the Swampland

We study the existence and stability of classical de Sitter solutions of type II supergravities with parallel Dp ‐branes and orientifold Op ‐planes. Together with the dilaton and volume scalar fields, we consider a third one that distinguishes between parallel and transverse directions to the Dp/Op . We derive the complete scalar potential for these three fields. This formalism allows us to reproduce known constraints obtained in 10d, and to derive new ones. Specifying to group manifolds with constant fluxes, we exclude a large region of parameter space, forbidding de Sitter solutions on nilmanifolds, semi‐simple group manifolds, and some solvmanifolds (at least in some standard algebra basis). In the small remaining region, we identify a stability island, where the three scalars could be stabilized in any de Sitter solution. We discuss these results in the swampland context.
Modeling the Curb Parking Price in Urban Center District of China Using TSM-RAM Approach

Parking demand forecasting is an important part of urban parking planning and is also an important basis for the development of parking facilities. The primary objective of this study was to explore multiple factors that affect the curb parking price (CPP) and the changing rules of the curb parking price (CPP) with these factors and to predict the CPP in terms of urban mobility. The data were collected through a statistical survey that was administered in 81 cities in China. The cities were divided into three categories: rich cities (RCs), poor cities (PCs), and tourist cities (TCs). Both the time series method (TSM) and regression analysis method (RAM) were developed to simultaneously examine the factors associated with the CPP among parking users. The results showed that TSM and RAM can account for common urban curb parking prices. The prediction results showed that the CPP is affected by the number of urban dwellers (UD), the prevalence of car ownership (CO), and the per capita disposable income (PCDI) of urban residents; the CPP can be predicted by a model built on the basis of the above three influencing factors. The results can enhance our understanding of the factors that affect CPP. Based on the results, some suggestions regarding the use of the CPP range in parking policy planning were discussed.
A basal archosaurian origin for birds

The controversy over the origin of birds may have been resolved through the discovery of new and remarkable fossils from the Triassic of Central Asia and the Early Cretacous of China. Flight probably originated in small, quadrupedal gliding archosaurs in the Triassic. Feathers originated for gliding rather than for insulation. The “maniraptoran dinosaurs” are actually derived from birds with at least gliding capabilities and primary feathers on the hands.
New Combinations in Combretaceae subtribe Combretinae from Africa and Asia

Recent molecular evidence has confirmed that Meiostemon and Quisqualis are embedded in Combretum. While some of the species in the two former genera have already been transferred to Combretum, several combinations are still wanting. New combinations for these species in Combretum are therefore formalised here for taxa of Meiostemon and Quisqualis that had not been formally transferred yet. Additionally, we list recently described taxa that are placed in Combretum subgenus Cacoucia section Quisqualis.
Oriented electrospun nanofibers on stand-alone multi-segmented cylindrical collectors

Abstract Single-segment collectors, commonly used in electrospinning, distribute nanofibers randomly over their entire length. To improve the orientation of resultant nanofibers, a multi-segmented collector has been developed having alternate conducting and nonconducting segments. The alignment principle is based upon the attraction of nanofibers towards conductive segments, while the nonconductive segments, having least attraction for nanofibers, do not pull the fibers toward themselves. This causes the nanofibers to stretch over the nonconductive segments, thanks to attractive forces from the adjacent conductive segments. The best orientation was obtained on the cylindrical collector with 12.5 mm nonconductive segment length, 20 mm conductive segment length and 11% polymer concentration. Different polymeric materials can be electrospun on these types of multi-segmented collectors with high fiber orientation for various applications.
A gradient in inner pressure of germline cells controls overlaying epithelial cell morphogenesis

How internal tissue growth impacts on surrounding epithelium is unknown. To address this, we used the Drosophila ovarian follicle, which is composed of a cluster of 15 anterior nurse cells and one oocyte, surrounded by epithelial cells. While the nurse cells grow, the epithelial cells covering them flatten progressively in anterior. We demonstrated that a gradient of cytoplasmic pressure, from anterior to posterior, is present in the nurse cells and that this gradient controls the timing and the wave of the epithelial cell flattening, by acting on TGFß. Our data indicate that intrinsic nurse cell growth is important to control nurse cell pressure. Finally, we revealed that nurse cell pressure, and subsequent TGFß activity, lead to enhanced follicle elongation in anterior and this is crucial to maintain nurse cell integrity. Cytoplasmic pressure is thus essential to shape autonomously and non-autonomously the cells during development.
Limited consequences of infestation with a blood-feeding ectoparasite for the nestlings of two North Pacific seabirds

The seabird tick Ixodes uriae parasitizes over 60 host species in the circumpolar regions of both hemispheres. To assess the impacts of these ticks on the growth and development of nestling seabirds, we used a logistic growth model to interpolate between successive measures of mass (g) and wing chord (mm) for 558 Cassin’s auklet Ptychoramphus aleuticus and 344 rhinoceros auklet Cerorhinca monocerata chicks over 11 years (1997–2008, less 2003) on Triangle Island, British Columbia, Canada. From the model, we estimated the asymptotic measure and the age at inflection point for each chick’s growth trajectory, and assessed their relationships with tick load relative to other sources of annual and seasonal variation in growth. Most chicks (72.4% of Cassin’s auklets, 62.2% of rhinoceros auklets) hosted ≥ 1 ticks, and the median tick load on infested chicks was two in both species. Infestation rates varied by a factor of about two among years (0.42 to 0.87 overall), but were uncorrelated between species and with air temperatures over the preceding winter. The probability of hosting a tick declined strongly with chick age, mainly in the first 20 days after hatching, and to near zero by fledging. Asymptotic weights and/or wing lengths declined with tick load in both species, but at normal loads the reductions were minor relative to those imposed by other factors; only at very high loads, which were rare, were effects likely to be biologically relevant. Tick load and survival to fledging were unrelated in both species. While our study found little influence of ticks, we believe there is need for further study of the relationships between parasites and seabird demography, especially in light of ongoing environmental change.
Controlled Release of Metformin Hydrogen Chloride from Stimuli-responsive Hydrogel based on Poly(N- Isopropylacrylamide)/Chitosan/Polyvinyl Alcohol Composite

Hydrogels are ideal biomaterials owing to their unique network structure that facilitates considerable hydrophilicity and biocompatibility. At the same time, hydrogels also possess soft physical properties when combined with living tissue. In this study, metformin hydrogen chloride (metformin HCl)-loaded stimuli-responsive poly(N-isopropylacrylamide) (pNIPAAm) –chitosan– polyvinyl alcohol (PVA) hydrogels were synthesized through a freezing and thawing procedure and subsequently subjected to gamma irradiation at room temperature. The gel content and the water absorption capacity of the synthesized hydrogels were analyzed. The polymer interaction in the matrix was observed by Fourier transform infrared spectroscopy, and the release of metformin HCl was studied in different pHs and temperatures. The hydrogels had 85% of the gel content and 373% of the water absorption capacity after 24 h of water immersion. The metformin HCl-loaded (pNIPAAm–chitosan–PVA) hydrogels demonstrated a sustained drug release profile over 7 h. The drug release exhibited pH-dependent and temperature-dependent behavior. The developed hydrogels showed good metformin HCl release ability at pH 3 and pH 6.86 at the temperature of 37oC. The results showed that pNIPAAm–chitosan–PVA hydrogels could be employed for controlled drug release of metformin HCl.
The Effect of Respiratory Rehabilitation Training on the Life Quality of Pneumoconiosis Patients

Objective: To explore the effect of respiratory rehabilitation training on the quality of life of pneumoconiosis patients. Methods: 76 pneumoconiosis patients who were treated in our hospital from April 2017 to December 2019 were selected as the research object, and randomly divided into 2 groups according to the order of admission by coin tossing, 38 cases in each group. The control group carried out health knowledge education on the basis of conventional treatment, and the observation group combined with respiratory rehabilitation training on the basis of the control group to compare the quality of life and lung function of the two groups of patients. Results: After 2 months of nursing care, scores of GQOLI-74 scale and pulmonary ventilation function indexes in the observation group were higher than those in the control group, with statistically significant differences (P<0.05). Conclusion: Respiratory rehabilitation training can improve pulmonary ventilation function of pneumoconiosis patients, improve the quality of life of patients, has good clinical application value.
Analysis of impact of Fadama III Additional Financing (AF1) on beneficiaries income and poverty alleviation in Abuja, Federal Capital Territory, Nigeria

The study assessed the impact of Fadama III AF‘s interventions on income and poverty alleviation of beneficiaries in Abuja Federal Capital Territory. A sample of one hundred and fifty respondents among the beneficiaries was drawn using multistage sampling technique. Descriptive and simple percentage was used to analyze the data. The sampled respondents were majorly males that represent 72% in their middle age-group, about 78% of them had western education. Farming was the major occupation among respondents (70%). Fadama III AF1 supported farmers with improved seed varieties, fertilizers, agrochemical, water pump, sprayer, advisory services and capacity building training. Although, the output translated to increased income and poverty alleviation among the beneficiaries, there is room for improvement, because the Fadama users are yet to operate at their full capacity. Based on these findings, the following recommendations were made: there is need to invest more on some infrastructural facilities as well as human resources development; for food supplies to remain stable and secured increase in income, there must be considerable improvement in agricultural technologies in order to increase crop yields, and organized market for the farmers to have stable price index for their produce. Keywords: Impact, Fadama III AF1, Poverty alleviation, financial intermediation.
Information Extraction from Electronic Medical Records using Natural Language Processing Techniques

Patients share key information about their health with medical practitioners during clinic consultations. These key information may include their past medications and allergies, current situations/issues, and expectations. The healthcare professionals store this information in an Electronic Medical Record (EMR). EMRs have empowered research in healthcare; information hidden in them if harnessed properly through Natural Language Processing (NLP) can be used for disease registries, drug safety, epidemic surveillance, disease prediction, and treatment. This work illustrates the application of NLP techniques to design and implement a Key Information Retrieval System (KIRS framework) using the Latent Dirichlet Allocation algorithm. The cross-industry standard process for data mining methodology was applied in an experiment with an EMR dataset from PubMed todemonstrate the framework. The new system extracted the common problems (ailments) and prescriptions across the five (5) countries presented in the dataset. The system promises to assist health organizations in making informed decisions with the flood of key information data available in their domain. Keywords: Electronic Medical Record, BioNLP, Latent Dirichlet Allocation
Which Institutional Conditions Lead to a Successful Local Energy Transition? Applying Fuzzy-Set Qualitative Comparative Analysis to Solar PV Cases in South Korea

To explore the most desirable pathway for a successful local energy transition, a fuzzy-set qualitative comparative analysis was conducted on 16 regional cases in South Korea. We developed four propositions based on previous studies and theories as a causal set. Based on the South Korean context, we selected the solar photovoltaic (PV) generation and solar PV expansion rate as barometers for measuring the success of a local energy transition. Our analysis highlights the importance of the International Council for Local Environmental Initiatives (ICLEI) membership (network), local legislation, and the environmental surveillance of locally-based non-governmental organizations (NGOs). The implications of this study will provide insights for developing or newly industrialized countries where an energy transition is underway.
Sensitivity of Botswana Ex-Tropical Cyclone Dineo rainfall simulations to cloud microphysics scheme

Background: Numerical weather and climate models rely on the use of microphysics schemes to simulate clouds and produce precipitation at convective scales. It is important that we understand how different microphysics schemes perform when simulating high impact weather to inform operational forecasting. Methods: Simulations a heavy rainfall event from 17-20 February 2017 over Botswana were made with the Weather Research and Forecasting (WRF) model using four different microphysics schemes. The schemes used were the Weather Research and Forecasting Single Moment 6-class scheme (WSM6); Weather Research and Forecasting Single Moment 5-class scheme (WSM5); Stony Brook University scheme (SBU-YLIN); and Thompson scheme. WSM5 is considered as the least sophisticated of the four schemes, while Thompson is the most sophisticated. Simulations were initialized and forced by the Global Forecast System (GFS), and configured with a grid spacing of 9km over an outer domain and 3km for a nested inner domain without the convection parameterization. The simulations were produced using the University of Botswana and the Centre for High Performance Computing (CHPC) High Performance Computing (HPC) systems. Results: WSM5 and WSM6 simulations are mostly similar; the presence of graupel in WSM6 did not result in large differences in the rainfall simulations. SBU-YLIN simulated the least amount of rainfall, followed by Thompson. All the schemes captured the north-south rainfall gradient observed on 17 February, but with all simulations rainfall is simulated slightly south of where it was observed. All the schemes overestimated rainfall on 18 February over the central parts of Botswana, and underestimated rainfall on 19 February over most of Botswana. Conclusions: Simulations with different microphysics looked more similar to each other, than to observations. Future studies will test WRF configurations including a single nest over Botswana to determine the best configuration for operational forecasting by the Botswana Department of Meteorological Services.
Interaction of Mitochondrial and Epigenetic Regulation in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a pathology preceded mainly by cirrhosis of diverse etiology and is associated with uncontrolled dedifferentiation and cell proliferation pro -cesses. Many cellular functions are dependent on mitochondrial function, among which we can mention the enzymatic activity of PARP-1 and sirtuin 1, epigenetic regulation of gene expression, apoptosis, and so on. Mitochondrial dysfunction is related to liver dis- eases including cirrhosis and HCC; the energetic demand is not properly supplied and mitochondrial morphologic changes have been observed, resulting in an altered metabo- lism. There is a strong relationship between epigenetics and mitochondrion since the first one is dependent on the correct function of the last one. There is an interest to improve or to maintain mitochondrial integrity in order to prevent or reverse HCC; such is the case of IFC-305 that has a beneficial effect on mitochondrial function in a sequential model of cirrhosis-HCC. In this model, IFC-305 downregulates the expression of PCNA, thymidylate synthase, HGF and its receptor c-Met and upregulates the cell cycle inhibitor p27, thereby decreasing cell proliferation. Both effects, improvement of mitochondria function and reduction of tumor proliferation, suggest its use as HCC chemoprevention or as an adjuvant in chemotherapy.
Hepatoprotective Effect Of Silymarin Against Diethylnitrosamine Induced Oxidative-Nitrosative Stress in Rats

Karaciger kanseri dunyada kanserle iliskili olumlerde ucuncu sirada yer almaktadir. Hepatoseluler karsinom (HSK) primer karaciger kanserlerinin %70-85’ini olusturmaktadir. Bu calismada; deneysel karaciger kanseri modelinde Dietilnitrozamin (DEN)'in rolunu arastirmayi ve silimarinin hepatoprotektif etkisini oksidatif-nitrozatif stres markerleri kullanarak immunohistokimyasal yontemlerle ayrintili olarak incelemeyi amacladik. Bu amacla 50 adet Wistar Albino cinsi erkek rat 10’arli 5 gruba ayrildi. DEN grubundaki hayvanlara 50 mg/kg dozunda haftada 1 kez deneme suresince DEN uygulamasi yapildi. DEN+silimarin grubundaki ratlara DEN uygulamasindan 1 hafta once baslayacak sekilde 100 mg/kg dozunda haftada 3 kez deneme suresince intraperitoneal yolla silimarin (propilen glikolde cozdurulmus) uygulandi. Kontrol grubundaki ratlara deneme suresince pelet yem ve icme suyu verildi. Sham grubundaki hayvanlara % 0.9 NaCl icerisinde cozdurulmus propilen glikol intraperitoneal yolla haftada 3 kez deneme suresince verildi. Silimarin grubundaki ratlara 100 mg/kg dozunda deneme suresince intraperitoneal yolla haftada 3 kez silimarin uygulandi. 21 haftanin sonunda DEN ve DEN+silimarin gruplarinda makroskobik olarak farkli buyukluk ve boyutlarda noduler yapilar tespit edildi. Mikroskobik incelemede nodullerin HSK olduklari belirlendi. Sonuc olarak DEN’in karaciger kanserini indukledigi; silimarinin ise iNOS ve Nitrotirozin ekspresyonlari acisindan istatistiksel olarak anlamli bir koruyucu etki gostermedigi belirlenmistir.
The extent to which kindergarten teachers in Zliten City schools have some positive indicators (psychological satisfaction, self-efficacy, and emotional effort) and its relationship to the level of mental health they have

The purpose of the present research is to examine the level of some concepts of positive psychology (psychological satisfaction, self-efficacy, emotional effort) with kindergarten teachers, and extract the relationship between the level of those concepts of positive psychology and level of mental health with 86 kindergarten teachers in Zliten city. The Psychological Satisfaction Scale and the Self-Effectiveness Scale had been used. Results show that kindergarten teachers have an acceptable level of psychological satisfaction, furthermore, high level of self-efficacy, and emotional effort, whilst, the level of mental health was within the average range, the results also showed positive related statistically significant between the concepts of positive psychology and mental health terms of Strength of the relationship were as follows: (emotional effort, psychological satisfaction, self-efficacy), these concepts have a moderate impact on the level of mental health, and this means that there are other factors that affect mental health in addition to these factors, which necessitate subsequent studies dealing with other variables. Furthermore, there are now statistically significant differences in the level of psychological satisfaction and the level of self-efficacy attributable to years of experience, while at the level of emotional effort there were differences due to the variable years of experience, as well as the existence of differences in the level of mental health attributable to years of experience.
Homogeneous pressure influences the growth factor release profiles in solid platelet-rich fibrin matrices and enhances vascular endothelial growth factor release in the solid platelet-rich fibrin plugs

Aims: Platelet-rich fibrin (PRF) exists in both solid and fluid forms. The present study was the first to evaluate the influence of homogeneous pressure on the growth factor (GF) release in pressed PRF-matrices and plugs. Methods and Material: A solid PRF-matrix (208 g; 8 min) was pressed to obtain a plug, and a pressed PRF-matrix that are used in clinical application. The released exudates were evaluated compared to liquid PRF (60 g and 3 min). The VEGF, TGF-ß1 and EGF release was quantified using ELISA. The fibrin structure and cellular components in solid PRF groups were evaluated histologically. Results: The pressed PRF-matrix and PRF-plug exhibited denser fibrin structure compared to the non-pressed PRF-matrix. On day 7, the PRF-plug and non-pressed PRF-matrix showed significantly higher release of VEGF, TGF-ß1 and EGF compared to that of the pressed PRF-matrix. The accumulated VEGF concentration was significantly higher in the PRF-plug compared to that in the PRF-matrix and non-pressed PRF-matrix. The accumulated EGF and TGF-ß1 concentrations over 10 days showed no statistically significant differences between the evaluated solid PRF groups. The exudates released TGF-ß1 and EGF passively, that was only detectable in after 1 and 7 hours. Liquid PRF released significantly higher GFs than the exudates at all investigated time points. The early VEGF and EGF release in liquid PRF (1 hour to 1 day) was significantly higher than that in the solid PRF-matrices. On day 10, significantly higher accumulated GFs were detected in the solid PRF groups compared to those in the liquid PRF. Thus, the combination of both solid and liquid PRF is a potential tool to generate a clinically relevant system with sustained bioactivity. Conclusions: These results highlight the potential to influence the GFs release profile of solid PRF matrices by pressure and obtain a clinically applicable plug with significantly higher VEGF release, providing further understanding of the release profile of PRF matrices as a drug delivery system.