Miracle-dz/UniFAR-FTUs huggingface dataset:
The Influence of Epicardial Fat and Nonalcoholic Fatty Liver Disease on Heart Rate Recovery in Metabolic Syndrome.

BACKGROUND Epicardial adipose tissues reflecting visceral fat accumulations of the heart are associated with metabolic syndrome (MetS) and can be a predictor of other cardiometabolic diseases. It can adversely influence autonomic nervous system (ANS) of heart. Heart rate recovery (HRR) is an easy method for measuring ANS dysfunction. The purpose of this study was to determine whether epicardial fat thickness (EFT) and nonalcoholic fatty liver disease (NAFLD) are related to HRR in patients with MetS. METHODS We enrolled 772 consecutive patients from a health-screening center who underwent abdominal ultrasonography, treadmill test, and cardiac echocardiography. EFT using echocardiography and HRR by symptom-limited exercise testing was assessed. According to the presence of MetS and NAFLD, patients were classified into the four groups. RESULTS In NAFLD patients, EFT was higher and HRR was lower, especially in patients with MetS and NAFLD, compared to non-MetS participants without NAFLD (MetS with NAFLD, EFT 7.5 ± 4.4 mm, HRR 31.9 ± 12.7; MetS without NAFLD, EFT 4.9 ± 3.0 mm, HRR 39.5 ± 11.1; non-MetS with NAFLD, EFT 5.9 ± 3.6 mm, HRR 36.6 ± 12.7; and non-MetS without NAFLD, EFT 4.4 ± 3.5 mm, HRR 43.4 ± 14.5, p < 0.001). Patients with severe liver steatosis (LS) showed significantly higher EFT than those with moderate LS (14.2 ± 2.0 vs. 7.5 ± 3.1 mm, P < 0.001), and EFT was positively correlated with severity of LS (r = 0.431, P < 0.001). HRR was significantly correlated with EFT (r = -0.386, P < 0.001) and severity of LS (r = -0.324, P < 0.001). CONCLUSIONS EFT and NAFLD were significantly correlated with HRR in patients with MetS and they may be highly related to increased cardiovascular risk. These results suggest a cross-link among EFT, NAFLD, and cardiac autonomic dysfunction in patients with MetS.
Willow: a system to automatically assess students’ free-text answers by using a combination of shallow NLP techniques

In this paper, a new approach to automatically assessing students’ short free-text answers is presented. It has been implemented into the multilingual web-based application called Willow. Willow is able to formulate a question (chosen randomly or according to the students’ personal features) and, to score the answer, written in Spanish or in English, by using a combination of shallow NLP techniques such as stemming, removal of closed-class words, word sense disambiguation or multiword term identification. Several experiments have been carried out to identify the best combination of techniques for each language to find the optimal configuration in each case.
Prostate Cancer Cells Produce Exosomes Modulating Metastasis to the Bones

Prostate cancer metastasis to the bone is a frightening cause of death world-wide. Patients do not live a functional and active life before they eventually die. The major reason for prostate cancer metastasis is the use of poor bio markers such as Prostatespecific antigen (PSA) and histopathological grading to diagnose prostate cancer incorrectly, indicating that a patient who has a stage four prostate has a benign tumor. New and effective markers for prostate cancer are urgently needed. The goal of this review is to examine modulation of prostate cancer (PCa) exosome interaction with prostate cancer micro-environment as a major support system to prevent incurable bone cancer. Conventional prostate cancer therapy is weakened by exchange of growth factors between cancer cells and it surroundings, leading to increase tumor growth and metastasis to other parts of the body. The surrounding of tumor includes prostate cancer exosomes, which can be release under suitable condition. Basically, the interactions between prostate cancer exosomes, growth factors and cell microenvironment support uncontrollable metastasis of prostate cancer to the bone. PCa exosome modification may be the solution to the increasing patient death caused by prostate cancer metastasis to the bone. PCa exosome is in the fore-front of research as a biomarker for early prostate cancer detection.
Benefits, need and importance of daily exercise

Regular Physical activity and exercise can help you stay healthy, energetic and independent as you get older. Exercise play avital role in preventing health diseases and stroke. The health benefits of doing regular Exercise have been shown in many studies. This paper review the evidence of the benefits of exercise for all the body systems. Physical activity and exercise can reduce stress and anxiety, boost happy chemicals, improve self-confidence, increase the brain power, sharpen the memory and increase our muscles and bones strength. It also helps in preventing and reducing heart disease, obesity, blood sugar fluctuations, cardiovascular diseases and Cancer.
State-of-the-art Versus Time-triggered Object Tracking in Advanced Driver Assistance Systems

Most state-of-the-art driver assistance systems cannot guarantee that real-time images of object states are updated within a given time interval, because the object state observations are typically sampled by uncontrolled sensors and transmitted via an indeterministic bus system such as CAN. To overcome this shortcoming, a paradigm shift toward time-triggered advanced driver assistance systems based on a deterministic bus system, such as FlexRay, is under discussion. In order to prove the feasibility of this paradigm shift, this paper develops different models of a state-of-the-art and a time-triggered advanced driver assistance system based on multi-sensor object tracking and compares them with regard to their mean performance. The results show that while the state-of-the-art model is advantageous in scenarios with low process noise, it is outmatched by the time-triggered model in the case of high process noise, i.e., in complex situations with high dynamic.
AE-Beitrag: Unikondylärer Ersatz vs. Totalendoprothese bei medialer Gonarthrose

Zusammenfassung Hintergrund Die isolierte mediale Gonarthrose ist eine Kniegelenkspathologie, die operativ sowohl den Einsatz eines unikondylären Oberflächenersatzes (Schlittenprothese) als auch die Implantation einer Totalendoprothese gestattet. Eine einheitliche Empfehlung, welches Verfahren bei dieser speziellen Indikation zu bevorzugen ist, fehlt jedoch. Material und Methoden In der vorliegenden Übersichtsarbeit sollen anhand der vorhandenen Literatur beide Verfahren bez. des klinischen Ergebnisses, des Langzeitüberlebens und der Komplikationsrate verglichen werden. Ergebnisse Bezüglich des klinischen Outcomes zeigen die meisten Studien eine Überlegenheit des unikondylären Oberflächenersatzes. Hier ist jedoch zu beachten, dass diese Patienten häufig auch präoperativ einen besseren Ausgangsbefund aufwiesen, das Maß an Verbesserung jedoch vergleichbar zur Totalendoprothese war. Betrachtet man das Survival, so zeigen Studien, Institutional Registries und landesweite Register eine klare Überlegenheit der Totalendoprothese in der Langzeithaltbarkeit. Als potenzieller Bias muss hier die höhere Revisionsfreudigkeit bei der Schlittenprothese beachtet werden. Bezüglich der Mortalitätsrate zeigt die Literatur eine Überlegenheit der Schlittenprothese. Die implantatspezifischen Komplikationen sind wiederum bei der Schlittenprothese höher. Schlussfolgerung Zusammengefasst ist eine klare Empfehlung für eines der beiden Verfahren aufgrund der Literaturlage nicht möglich. Das tendenziell bessere klinische Outcome und die niedrige Mortalitätsrate sprechen für den unikodylären Oberflächenersatz, während beim Langzeitüberleben und den implantatbedingten Komplikationen die Totalendoprothese im Vorteil ist.
Development of “Presence” Measures for Virtual Environments

A primary argument for the efficacy of Virtual Environments (VE) applications is that the user is "present" in the simulated environment. Presence is defined as the subjective experience of being in one environment (there) when one is physically in another environment (here). Presence is probably a normal awareness or attentional phenomenon based in an interaction between external or immersive factors and internal tendencies. These same factors support the transition to or experience of presence in a remote or artificial environment. Major imersive factors identified in current literature have been used as the basis for two different questionnaires. The Immersive Tendencies Questionnaire (ITQ) was developed to identify possible behavioral correlates or indicators for experiencing presence in artificial environments. The Presence Questionnaire (PQ) was developed to address both the extent of involvement in a VE experience and the effect of different factors or features of the virtual environment. Results of questionnaire administrations in conjunction with experiments into basic task performance and building interior route learning in VE indicate reasonable reliability values (Cronbach's alpha) for both the ITQ ( . 7 5 ) and PQ ( . 8 0 ) . The PQ and ITQ correlate significantly (r=.31, N=132, P<.OOl). Several subscales were revealed in Cluster analyses on each questionnaire. Preliminary investigations with a priori subscales indicate relationships with movement/manipulation task performance. Correlations between the PQ and a standard Simulator Sickness measure reveal significant negative correlations between the overall scores and several subscales. Analyses of data from three experiments are presented in connection with revisions made to the questionnaires.
Tools for visual scene recognition

Scene recognition is an important step towards a full understanding of an image. This thesis presents novel ideas related to semantic-spatial content capture and local-global feature fusion techniques and applies them for scene recognition. It shows how the proper use of these approaches, without trying to recognize objects in the scene images, can lead to improvement in recognition accuracy for scene classification. First, we propose a method to build a semantic visual vocabulary. The features are extracted from the image patches and the initial vocabulary is constructed by performing k-means clustering on the extracted features and choosing the cluster centers as the visual words. The feature vectors are quantized based on the initial vocabulary to form a wordimage matrix that describes the occurrence of words in the images. The codebooks are then embedded into the concept space by latent semantic models. We demonstrate this embedding using Latent Semantic Analysis (LSA) as well as Probabilistic Latent Semantic Analysis (pLSA). In the proposed space, the distances between words represent the semantic distances, which are used to construct a discriminative and semantically meaningful vocabulary. The main contributions of the first chapter are as follows: 1. Using semantic word space to co-cluster similar words together to form a semantic visual vocabulary. This will improve the results compared to other methods that use document space directly after pLSA embedding. 2. Investigating changes in the number of latent variables. 3. Using LSA embedding when all other vision systems to date only use pLSA. This method has shown promising results on 15-Scene categories when the proposed model extracts one type of visual feature. Second, since fusing local and global features is beneficial for achieving a promising performance for scene categorization systems [7], we propose a novel Local-Global Feature Fusion (LGFF) method with the capability to fuse latent semantic patches adaptively.
Effect of Starvation Times on Blood Glucose of Mother and her Full Term Newborn before Spinal Anesthesia for Elective Cesarean Section

1Professor, Department of cardiothoracic & Vascular Anaesthesiology NRS Medical College, India 2Assistant Professor, Department of community Medicine, India 3Senior Resident, Department of Anaesthesiology, India 4Professor & Director, Directorate General Medical Services (Army) Adjuvant General’’s Branch, India 5Assistant Professor, Department of Anaesthesiology, Midnapur Medical College, India 6Consultant, Department of Anaesthesiology, AMRI Hospital, India 7Assistant Professor, Department of GI Anaesthesiology, India
Zur Bewertung spontaner Atemänderungen bei der Respirations-Olfaktometrie

Zusammenfassung Einleitung Durch Gerüche evozierte Atemänderungen werden zum objektivierenden Nachweis der Intaktheit des Riechsystems im Sinne einer Respirations-Olfaktometrie genutzt. Spontane Atemänderungen lassen sich in der Regel nicht von evozierten unterscheiden. Es müssen deshalb wiederholt Reize mit reinen Riechstoffen randomisiert mit Leerreizen in die Ruheatmung appliziert werden, um mehrheitliche Atemänderungen bei olfaktorischer Reizung darzustellen. Methodik Bei 26 erwachsenen Normosmikern wurden mit Hilfe eines Fluss-Olfaktometers 15 überschwellige H2S- und 15 Neutralluft-Reize (Dauer: 2 s) randomisiert mit einem Interstimulusintervall von mindestens 1 Minute inspirationssynchron appliziert. Vor der Reizung durfte die Ruheatmung nicht sehr streuen (Variationskoeffizient der Dauer der Inspiration und der Exspiration ≤0,1). Eine respiratorische Reaktion im Reizatemzug lag vor, wenn die Dauer der Inspiration (DIN) bzw. der Exspiration (DEX) des Reizatemzuges jenseits der doppelten Standardabweichung dieser Atemparameter vom Mittelwert der fünf vorausgehenden Ruheatemzüge lag. Die Anzahl der Reaktionen wurde auf die Anzahl der Reize und der off-line als regelmäßig ermittelten Ruheatemkomplexe normiert und Reaktionsindizes gebildet. Ergebnisse H2S-Reize evozierten deutlich mehr Atemänderungen als Neutralluftreize. DIN und DEX verringerten sich bei olfaktorischer Reizung häufiger als bei einer Applikation von Neutralluft. Verlängerungen von DIN und DEX waren zwischen den beiden Reizqualitäten nicht different. Schlussfolgerungen Nur die randomisierte nasale Reizung mit einem Riechstoff und einem Leerreiz machen die Respirations-Olfaktometrie aussagefähig.
Stroke-to-stroke matching in on-line signature verification

On-line Signature Verification is a field of verifying the time series signature data that normally obtained from the tablet-based device. Unlike common signature image, the on-line signature image data consists of points that are arranged in sequence based on time. The aim of this research is to develop a new approach to map the strokes in both test and reference signatures as well as to verify the originality of the test signatures. Current methods make use of the DTW algorithm and its variant to segment them before comparing each of its data dimension. This project suggesting a modified DTW algorithm with the proposed Missed Nodes Recovery Algorithm aims to improve the mapping performance, hence the development of stroke to stroke signature comparison is possible. This project is also proposing a method to compare the strokes with its similar strokes in on-line signature. All algorithm and experiments will be carried out using Matlab. The output of this research project is an algorithm that can be used to map strokes as well as to compare similarity of strokes in on-line signature.
Proceedings of the 18th annual international conference on Mobile computing and networking

Welcome to Istanbul and to ACM MobiCom 2012, the 18th Annual Conference on Mobile Computing and Networking. MobiCom is known for top-quality research in mobile computing and networking, and this year is no different. The technical program represents the center of gravity of the conference, and is the result of a seven-month-long effort on behalf of the organizers---and even longer than that on behalf of the submitting authors. We are delighted with this year's program and hope you have a stimulating, enjoyable, and fruitful experience at the conference! The Call for Papers attracted 212 papers submissions from 26 countries, out of which 32 were selected for inclusion in the program. All papers (except for a small handful that were rejected without review due to format violations) received three initial reviews, and 110 manuscripts were selected for further consideration. These papers received an additional set of reviews, and an online discussion identified 70 manuscripts for further discussion at the in-person PC meeting. The TPC assembled in Austin, Texas, where we crafted the final program over the course of two days. Each paper was reviewed in a double-blind fashion, and TPC members with conflicts of interest were excused from the room during discussion. A senior TPC member managed the review process for papers authored by either of the TPC co-chairs. We would like to thank the TPC members for their hard work and dedication to the review process. This year marked a return to a smaller PC, which we believe led to increased consistency and a higher energy level in the TPC meeting, but also resulted in a larger reviewing load for the individual members: The average TPC member reviewed 25 papers. We also required attendance at the TPC meeting, which involved significant travel for many international members. Despite the jet lag, the discussions were heated and productive, and we hope you enjoy the results. Due to logistical constraints, this year's publication schedule was more compact than most. We appreciate the willingness of the authors and shepherds to meet the resulting challenges, including a last-minute change in camera-ready formatting, which led to a slightly more varied paper length in this year's proceedings than is typical.
A WSN Vibration Sensor Nodes Optimization Placement Strategy in Nuclear Power Plant Equipment Monitoring Application

Vibration monitoring of equipment is vital to ensure reliable operation of nuclear power plant. Wireless sensor network can reduce monitoring cost, expand monitoring scope, and improve monitoring quality, and vibration sensor nodes placement is a key technology to guarantee the accuracy and correctness of vibration data acquisition and further analysis. Current placement researches are unable to meet the requirements of nuclear power plant application. In this paper, we first describe the problem and present its mathematical model, and then we developed a strategy based on genetic algorithm to address this problem. Considering constraints of Modal Information, sensitive nuclear power plant devices, connectivity, security, maintenance convenience, and placement convenience, we compare artificial placement, random placement, and our placement algorithm. Results show that fitness value of artificial placement and random placement is respectively 1.18 and 1.55 times as large as our algorithm's. We also test the impact of cross probability, mutation probability, and population size on our algorithm. Simulation results show that our algorithm is efficient, with run time 16% of enumeration algorithm.
Clinical Features of Nivolumab-Induced Thyroiditis: A Case Series Study.

BACKGROUND The programmed cell death-1 (PD-1) pathway is a novel therapeutic target in immune checkpoint therapy for cancer. It consists of the PD-1 receptor and its two ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). Nivolumab is an anti-PD-1 monoclonal antibody approved for malignant melanoma, advanced non-small cell lung cancer, and advanced renal cell carcinoma in Japan. Thyrotoxicosis and hypothyroidism have both been reported in international Phase 3 studies and national post-marketing surveillance of nivolumab in Japan. METHODS This study analyzed five consecutive cases with thyroid dysfunction associated with nivolumab therapy. Second, it examined the mRNA and protein expressions of PD-L1 and PD-L2 by reverse transcription polymerase chain reaction and Western blotting. RESULTS All patients were diagnosed with painless thyroiditis. Thyrotoxicosis developed within four weeks from the first administration of nivolumab and normalized within four weeks of onset in three of the five patients. Hypothyroidism after transient thyrotoxicosis developed in two patients, and preexisting hypothyroidism persisted in one patient. The other two patients were treated with glucocorticoids and discontinued nivolumab therapy for comorbid adverse events. One did not develop hypothyroidism, and the other developed mild, transient hypothyroidism. In addition, it was verified that normal thyroid tissue expresses PD-L1 and PD-L2 mRNA and those proteins. CONCLUSIONS In the present cases, nivolumab-induced thyrotoxicosis seemed to be associated with painless thyroiditis, while no patient with Graves' disease was observed. A transient and rapid course with subsequent hypothyroidism was observed in nivolumab-induced thyroiditis. In addition, it was verified that PD-L1 and PD-L2 are expressed in normal thyroid tissue. This suggests that nivolumab therapy reduces immune tolerance, even in normal thyroid tissue, and leads to the development of thyroiditis. Treating thyrotoxicosis with only supportive care and considering levothyroxine replacement therapy once subsequent hypothyroidism occurs is proposed. Further investigations are required to confirm whether glucocorticoid therapy and discontinuation of nivolumab therapy prevent subsequent hypothyroidism.
Single‐source dual‐layer amorphous IGZO thin‐film transistors for display and circuit applications

In this study, the authors report on high‐quality amorphous indium–gallium–zinc oxide thin‐film transistors (TFTs) based on a single‐source dual‐layer concept processed at temperatures down to 150°C. The dual‐layer concept allows the precise control of local charge carrier densities by varying the O2/Ar gas ratio during sputtering for the bottom and top layers. Therefore, extensive annealing steps after the deposition can be avoided. In addition, the dual‐layer concept is more robust against variation of the oxygen flow in the deposition chamber. The charge carrier density in the TFT channel is namely adjusted by varying the thickness of the two layers whereby the oxygen concentration during deposition is switched only between no oxygen for the bottom layer and very high concentration for the top layer. The dual‐layer TFTs are more stable under bias conditions in comparison with single‐layer TFTs processed at low temperatures. Finally, the applicability of this dual‐layer concept in logic circuitry such as 19‐stage ring oscillators and a TFT backplane on polyethylene naphthalate foil containing a quarter video graphics array active‐matrix organic light‐emitting diode display demonstrator is proven.
A Survey on CORDIC Algorithm Implementations Using Different Number Format

CORDIC (Coordinate Rotation Digital Computer) algorithm is to be utilized on computerized workstations to execute complex scientific operations and trigonometric functions. This calculation has been utilized for proficient execution of vector rotation operations in hardware.In present day workstation frameworks (military frameworks, restorative provisions, and so on.) complex scientific operations and trigonometric counts are generally utilized. It is executed simply by table look-up, shift and add operations. In this study, two architectures called FP- CORDIC and IQ-CORDIC have been conceived to actualize CORDIC calculation. These architectures have been acknowledged with IEEE-754 and IQ-Math number designs. Likewise they are contrasted concurring with execution time, process precision and fittings execution criteria on FPGA.