Miracle-dz/UniFAR-FTUs huggingface dataset:
Design of 433 MHz compatible matching network of wake-up receiver for wireless sensor node

Wireless Sensor Networks (WSNs) transpire in the last ten years as a revolutionary technology. The WSNs provide diverse opportunities in a wide variety of applications from environmental monitoring, healthcare to agriculture and industry. In several WSN scenarios, battery powered nodes should operate for years, that necessitate the requirement for advanced power management of the radio. Among all the node functions such as sensing, actuation and computations, the wireless communication energy is still a pre-dominant component. Therefore, the energy dedicated to communication of wireless sensor node should be preserved. Different techniques have been proposed targeting low power communication and short interrupt latency. This work aims at designing 433 MHz compatible matching network and low power Wake-Up Receiver (WUR) for wireless sensor node as a future work. WUR are the hardware technologies enabling a promising solution for WSN. This is achieved through Wake-Up Interrupt (WUp-Int) technique. As a part of this work the matching network is modeled and simulated using Advanced Design System (ADS). It operates in 433 MHz ISM band and the sensitivity achieved is -32 dBm while receiving 128Kb/s OOK modulated wake-up signal.
Evidence for a Triple Helix Recognition Site in the Hemopexin‐like Domains of Human Fibroblast and Neutrophil Interstitial Collagenases a

The metabolic turnover of the major protein constituents of the extracellular matrix is catalyzed by a family of enzymes called the matrix metalloproteinases (MMP). ' Two members of this gene family, human fibroblast collagenase (HFC) and human neutrophil collagenase (HNC), are capable of hydrolyzing the fibrillar type I, 11, and I11 collagens at an appreciable rate under physiological conditions. They do so in a highly specific and characteristic manner by making a single scission across all three alpha (a) chains of the triple helical tropocollagen (TC) monomers at a specific, sensitive locus approximately three-quarters from the N-terminus to produce TCA and TCB fragment^. ^,^ This reaction is the committed step in collagen turnover. At body temperature, the TC" and TCB fragments subsequently dissociate from the collagen fibrils, denature into unordered gelatin chains, and are hydrolyzed into smaller peptides by synergistic proteinases. The unique mode of cleavage of the interstitial collagens by human collagenases is one of the most specific and remarkable events in enzymology. The interstitial collagens are the most abundant proteins in humans, and HFC and HNC are the only two enzymes that are able to catalyze this specific cleavage. Conversely, only the interstitial collagen types I, 11, and I11 are susceptible to this extremely specific attack. The underlying structural basis for this recognition is not well understood, but must be related to the local conformation of the collagen substrates at the cleavage site. In an earlier study, we presented a hypothesis to explain the cleavage site specificity of tissue collagena~es. ~ According to this model, the cleavage site is in an apolar region of these collagens located at a boundary between an imino acid-rich, tightly triple helical segment and a loosely wound, imino acid-deficient section. The loose region on the carboxyl side of the scissile peptide bond allows the individual a chains to be unwound and bind at the active site of the collagenases in order to allow the catalytic, bond-breaking step to proceed. The tight triple helical segment, on the amino terminal side, is believed to be a recognition site that facilitates the binding of
Issues on Solar-Generator Interfacing With Current-Fed MPP-Tracking Converters

The large-scale harvesting of solar energy is an important action to decelerate the observed climate changes. Reliably operating solar-energy systems composing of solar arrays and their interfacing converters are of prime importance to maximize solar-energy harvesting. The paper investigates the solar-generator interfacing in terms of current-fed (CF) maximum-power-point (MPP) tracking converter. The investigations show that the CF converter under input-voltage control can usually operate from the short-circuit to open-circuit conditions of the solar generator without stability problems. When the output voltage or current has to be controlled constant, the converter may become unstable at the MPP due to the negative incremental resistance appearing at its input terminals. In practice, this means that the operating range of the CF converter has to be limited to the voltages less than the MPP voltage, when the output-voltage or current control is active. Practical evidence is provided based on a CF superbuck converter derived from the corresponding voltage-fed converter applying duality-transformation methods and supplied by an actual solar panel.
HIV behavioural risks and the role of work environment among Chinese male sex workers in Hong Kong

Abstract Male sex workers are a highly marginalised group in Hong Kong and it is increasingly so with an influx of them travelling from mainland China to work as “freelance” sex workers. This study aimed to measure important work environment variables that might affect the likelihood of condom use among male sex workers working in Hong Kong. A cross-sectional survey of 161 participants recruited by snowball and convenience sampling methods through outreach workers of a local non-governmental organization was conducted in 2007–2008. Only 27.4%, 54.7% and 42.6% reported consistent condom use when engaging in oral, anal and vaginal sex, respectively. Logistic regression shows unsafe sex was nearly four times (OR=3.41; 95%CI 1.51–7.69) as common in institutionalised male sex workers as among their independent counterparts. Lack of condoms provided at workplaces was a major barrier in this socio-legal context and was strongly associated with condom non-use amongst institutionalised sex workers (OR= 10.86; 95%CI 2.94–40.17). The present study finds that when compared with independent Male sex workers (MSWs), institutionalised MSWs were older, less educated, earned a higher income but more likely to engage in unsafe sex with their clients and their partners. Public health physicians must work with law-enforcing authorities to provide clear guidelines to remove these HIV prevention barriers.
Optic disc dimensions, body length, and body weight

Editor,—In the optic disc, all visual afference originating in the photoreceptors of more than 1000 mm2retina is concentrated on an area of about 2 mm2 to 3 mm2. The retinal ganglion cell axons are nowhere else so densely and tightly packed as in the optic nerve head. It explains the importance of the optic disc for anomalies and diseases of the optic nerve. Regarding the marked interindividual variability of the size of the optic disc,1 we undertook the present study to evaluate whether the dimensions of the optic disc are correlated with the length and weight of the whole body. ### CASE REPORT The study included 517 white subjects (243 women, 274 men) with a mean …
What is the association between the different components of stroke rehabilitation and health outcomes?

Objectives: To describe the rehabilitation input stroke patients received from health professionals during the early post stroke period and to explore possible associations between health outcomes and these rehabilitation inputs. Design: Community-based study with prospective identification of stroke patients from a random sample of 24 general practices stratified by geographical area and practice size. Setting: Ayrshire and Arran Health Board area, West of Scotland. Interventions: All physiotherapy, occupational therapy, dietetics, podiatry, speech and language therapy and community nursing inputs given to stroke patients in the course of normal treatment were recorded. Outcome measures: Barthel Index and Medical Outcomes Study Short Form-36 (SF-36). Both recorded at one, three and six months post stroke. Results: Of the 152 people providing data, more had received physiotherapy than any other rehabilitation input at all three follow-ups (81%, 47%, 39%), with occupational therapy being the next most common service (65%, 44%, 25%). Amount of rehabilitation input was significantly negatively correlated with health outcomes measured at each discrete time point: those patients with the poorest outcomes received greatest input. However, regression analysis of change in outcome scores showed that increasing amounts of rehabilitation input were significantly associated with a reduction in disability, particularly between one and three months post stroke. Conclusions: Not only have we shown that those stroke patients with poorest outcomes received most rehabilitation input, but, from analysis of the individual rehabilitation inputs, we have identified some rehabilitation inputs that significantly predict improved outcomes. This suggests that there would be merit in further investigation of these associations.
Workplace wellbeing programmes and their impact on employees and their employing organisations: a scoping review of the evidence base

This report constitutes a scoping literature review that identifies and critically examines the evidence base surrounding health and wellbeing programmes conducted in the workplace and their impact on employees and their employing organisations. The review drew on a broad range of sources covering multiple sectors. However, the report additionally highlights evidence that relates specifically to the retail and construction industries. The review offers an analysis of the current evidence base and discusses the implications of implementing different types of workplace health and wellbeing schemes. Some recommendations for supporting and promoting the health and wellbeing of employees in organisations are made on the basis of this review and, where gaps in knowledge are identified, recommendations for further research are made.
Impaired Glucose Homeostasis in Adult Rats From Hyperglycemic Mothers

The purpose of our study was to investigate whether nondiabetic gestationai hyperglycemia during fetal life could have additional effects on glucose homeostasis and insulin secretion in the adult rat. Hyperglycemia without the main other metabolic disorders and vascular injuries associated with diabetes was produced in unrestrained pregnant rats by continuous glucose infusion during the last week of pregnancy. Control rats were infused with distilled water. Compared with controls, the newborns from hyperglycemic rats were hyperglycemic and hyperinsulinemic. When studied longitudinally up to 3 mo, they showed slightly but significantly increased basal plasma glucose levels and normal basal insulin concentrations compared with controls. Glucose tolerance and insulin secretion in response to a glucose load (0.5 mg/kg, i.v.) were altered: Plasma glucose values were more increased at 5 min and remained higher 90 min after glucose injection; incremental plasma insulin values and the insulinogenic indexes (ΔIRI/ΔG) were always lower in rats from hyperglycemic mothers than in controls. These alterations were more and more marked with advancing age (1–3 mo). These data show that gestationai hyperglycemia may lead to persistent impairment of glucose homeostasis and insulin secretion in the adult rat.
Experience within ETSI of the combined roles of conformance testing and interoperability testing

Traditionally, conformance testing has been the domain of the telecommunications industry while interoperability testing has mainly been limited to the Internet world. Many see these as either/or solutions, ignoring the fact that recent experience shows that both approaches have their strengths when used wisely. We look at the growing trend in combining conformance testing with interoperability testing. We discuss the merits and shortcomings of each approach and show one way they can usefully be combined to maximise the effectiveness of the testing process. This is especially relevant where testing is being treated as a potential branding issue by various fora, as is the case for SIP and IPv6 among others. We also present ETSI standardisation activities such as STF 224 (which is developing a generic interoperability testing methodology), the recently created MTS IP Testing group and the work being done by the ETSI Protocol and Testing Competence Centre (PTCC) and the ETSI Plugtests/spl trade/ service.
Problems with solutions: drowning in the brine of an inadequate knowledge base.

BACKGROUND & AIMS We undertook a telephone questionnaire to determine current fluid prescribing practices and relevant knowledge among surgical preregistration house officers (PRHOs) and senior house officers (SHOs) working in 25 British hospitals. METHODS One hundred PRHOs were surveyed within 10 days of starting their first job (Group A). Fifty other PRHOs were surveyed 6-8 weeks after starting their first job(Group B) along with 50 surgical SHOs (Group C). Outcome measures included responsibility for prescribing, knowledge of the composition of common intravenous fluids and the principles governing their use. RESULTS PRHOs were responsible for prescribing in 89% of instances. Only 56% of respondents stated that fluid balance charts were checked on morning ward rounds. Less than half were aware of the sodium content of 0.9% saline or the daily sodium requirement. Although potassium supplements were usually correct, 25% of respondents prescribed two or more litres of 0.9% saline per day, which is far in excess of normal requirements. Although SHOs were more confident (P<0.0001), there was no significant difference between the three groups for most responses. CONCLUSIONS Inadequate knowledge and suboptimal prescribing of fluid and electrolytes is common. Undergraduate and postgraduate training in this basic patient management skill needs improvement, with particular emphasis on the practical aspects.
Design of tracked robot with remote control for surveillance

For specific purpose, tracked robot that can be controlled remotely and able to acquire images from environment is very important, for example in rescuing disaster victims. We propose architecture for Raspberry pi and AVR-based mobile robot that can be controlled by low cost remote controller Integrated Circuits(IC) and able to avoid obstacles using ultrasonic distance sensor. This prototype also can be used for education and research in the university. We evaluate the performance of the robot in terms of the distance and the capability to deliver video streaming from the output raspberry pi and 2.4 GHz Video transmitter.
Next generation ontology browser

The eleven million concept names integrated within the Unified Medical Language System (UMLS), developed and maintained by the U.S. National Library of Medicine, make it an unparalleled resource in biomedical sciences. A resource that due to its sheer complexity remains often underused. We developed a state of the art UMLS browser with a specific clinical focus on the three clinical terminologies: SNOMED CT, LOINC, and RxNorm. These terminologies are quickly becoming the cornerstone of U. S. health information interchange fuelled by the Meaningful Use legislation. While earlier works have shown the usefulness of each of these ontologies separately, this is the first work that demonstrates all three integrated into a single, data-driven workflow. A demo of the application (user: icbodemo, password: icbodemo) is available from: https://clinminer.hmgc. mcw.edu
Are all glaucoma drugs equally effective?

Purpose It is only in the recent years that we have got evidence that reducing intraocular pressure (IOP) is beneficial in terms of preventing glaucoma progression in all types of glaucomatous disease. Nowadays we do have numerous data from large clinical outcomes trials clearly indicating that the lower the IOP the better the visual field preservation. There is, however, less data available comparing outcomes of different pharmacological regimen.
Comprehensive health status assessment of centenarians: results from the 1999 large health survey of veteran enrollees.

BACKGROUND Information on the health status of centenarians provides a means for understanding the health care needs of this growing population. Therefore, we examined the health status of a national cohort of centenarian veteran enrollees. METHODS Ninety-three centenarian veteran enrollees returned a complete health history questionnaire, which included questions about sociodemographic information, age-associated conditions, health behaviors, health-related quality of life as measured by the Veterans SF-36, and change in health status. RESULTS Centenarian veteran enrollees are a group with major impairment across multiple dimensions of health-related quality of life despite having a relatively low prevalence of diseases. They had considerable physical limitations as reflected by their physical health summary scores (26.2 +/- 8.3). However, their mental health was comparatively good (mental health summary score 44.1 +/- 12.5). Compared to younger elderly veterans (ages 85-99), centenarians had a lower prevalence of hypertension, angina or myocardial infarction, diabetes, and chronic low back pain (p <.05). Centenarians had significantly worse physical functioning, role physical, vitality, and social functioning scores than did younger elderly veterans. The two groups did not differ in their general health, bodily pain, role emotional, and mental health scores. Centenarians did not perceive much decline in their physical or mental health during the preceding year. CONCLUSIONS Centenarian veteran enrollees are a group with a low number of age-associated diseases and good mental health despite substantial physical limitations. These results support future studies of services directed toward improvement of function as opposed to those focused solely on the treatment of diseases.
A white matter disorder in dementia of the Alzheimer type: A pathoanatomical study

In cases of Alzheimer's presenile and senile dementia, Alzheimer's disease (AD) and senile dementia of the Alzheimer type (SDAT), respectively, we have observed, in addition to the gray matter degeneration, a lesion that has the character of an incomplete infarction confined to the white matter. It is encountered in 60% of both groups, with mild changes in two thirds and moderate or severe changes in one third. It involves the deep white matter symmetrically, tapering off toward the cortex. It is characterized by partial loss of myelin, axons, and oligodendroglial cells; mild reactive astrocytic gliosis; and sparsely distributed macrophages as well as stenosis resulting from hyaline fibrosis of arterioles and smaller vessels. No complete or cavitating infarctions and no hypertensive vascular changes were observed. The white matter changes are thought to be due to hypoperfusion of the concerned white matter territories since, in addition to the white matter hyaline vascular stenosis, these cases show signs of cardiovascular disease, usually with hypotension.
Frustrated bilayer smectic phase in main-chain polymers with two different spacers

We have studied the structural characteristics of the smectic phases formed by the main-chain type of polymers in which the mesogenic biphenyl moieties are linked by two different odd-numbered aliphatic spacers in a regularly alternate fashion. The first interesting result of this study is that the two different types of layer structures are formed depending on the difference in the lengths of two aliphatic spacers. In the polymers with the two spacers having a small difference in their lengths, the single layer structure is formed as a result of the random mixing of the two different spacers. In contrast, if there is a sufficiently large difference in lengths, the two different spacers participate into different layers and so the smectic phase appears to have a bilayer character. The second interesting result is that the bilayer smectic phase pretends the frustrated structure with the unusual density modulation in the direction parallel to the layer. This frustrated structure has been explained as resulting from a twodimensional escape of the spontaneous polarization
IV/IT hUC-MSCs Infusion in RRMS and NMO: A 10-Year Follow-Up Study

Background: Stem cell transplantation is emerging as a potential therapeutic strategy in several autoimmune diseases. However, the safety and feasibility of long-term combined intravenous (IV) and intrathecal (IT) administration of hUC-MSCs in relapse remitting multiple sclerosis (RRMS) and neuromyelitis optica (NMO) is largely unknown. Objectives: In this study, we followed up the long-term safety and feasibility of combined IV and IT human umbilical cord mesenchymal stem cells (hUC-MSCs) transplantation in patients with RRMS and NMO. Methods: Five NMO patients and 5 RRMS patients were treated intravenously (4 times) and intrathecally (3 times) over a 21-day period with low-dose allogeneic umbilical cord blood–derived MSCs. All of the patients were monitored regularly by an investigator in a blinded manner to access the Expanded Disability Status Scale, MRI characteristics, and adverse events every 3 months within 12 months and once every year thereafter for 10 years after transplantation. Results: During the long-term follow-up, our data suggested that combined IV and IT administration of hUC-MSCs transplantation is safe and feasible. None of the intolerant adverse events, such as tumor formation and peripheral organ/tissue disorders, were observed throughout the 10-year follow-up. Conclusions: These data suggest that combined intravenous and intrathecal low-dose hUC-MSCs transplantation is safe and feasible in RRMS and NMO patients in the long term. The conclusion requires confirmation by future clinical trials in a larger cohort.
Dexamethasone‐induced leucocytosis in pregnancy

The effect of intramuscular dexamethasone administration in late pregnancy on the maternal peripheral white cell count was examined in 20 women. The mean total white cell count increased from a baseline of 11–3 × 109/L (SD 2–3) to 16–2 × 109/L (SD 4–6) on day 1, normalising thereafter. This 43% increase represented composite changes in the neutrophil and lymphocyte counts which, on average, increased by 62% and decreased by 22%, respectively. It is concluded that prenatal dexamethasone induces a significant neutrophilia on the first day following administration. This information may be helpful when monitoring for infection.
A computer linear regression model to determine ventilatory anaerobic threshold.

The anaerobic threshold has generally been determined by simple visual inspection of ventilation or other gas-exchange data obtained during incremental exercise. To establish objective criteria for the determination of anaerobic threshold, a computer algorithm has been developed that models the ventilatory response to exercise using multisegment linear regression. The best-fit regression model is chosen by minimizing the pooled residual sum of squares . The anaerobic threshold is reported as the first break point in that model. The computer-determined anaerobic threshold values for 37 subjects were compared with subjectively determined values as chosen by four independent observers. The observers' estimates, when pooled to yield a single a single value for each subject, gave a mean value for the gas-exchange anaerobic threshold of 2.26 +/- 0.69 l/min. The estimates by the computer method averaged 2.21 +/- 0.65 l/min. The correlation coefficient for these two methods was 0.94.