Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effects of Ibuprofen on Delayed Muscle Soreness and Muscular Performance After Eccentric Exercise

The purpose of this study was to examine the effects of ibuprofen on delayed onset muscle soreness (DOMS), indirect markers of muscle damage and muscular performance. Nineteen subjects (their mean [ ± SD]age, height, and weight was 24.6 ± 3.9 years, 176.2 ± 11.1 cm, 77.3 ± 18.7 kg) performed the eccentric leg curl exercise to induce muscle soreness in the hamstrings. Nine subjects took an ibuprofen pill of 400 mg every 8 hours within a period of 48 hours, whereas 10 subjects received a placebo randomly (double blind). White blood cells (WBCs) and creatine kinase (CK) were measured at pre-exercise, 4–6, 24, and 48 hours after exercise and maximal strength (1 repetition maximum). Vertical jump performance and knee flexion range of motion (ROM) were measured at pre-exercise, 24 and 48 hours after exercise. Muscle soreness increased (p < 0.05) in both groups after 24 and 48 hours, although the ibuprofen group yielded a significantly lower value (p < 0.05) after 24 hours. The WBC levels were significantly (p < 0.05) increased 4–6 hours post-exercise in both groups with no significant difference (p > 0.05) between the 2 groups. The CK values increased (p < 0.05) in the placebo group at 24 and 48 hours postexercise, whereas no significant differences (p > 0.05) were observed in the ibuprofen group. The CK values of the ibuprofen group were lower (p < 0.05) after 48 hours compared with the placebo group. Maximal strength, vertical jump performance, and knee ROM decreased significantly (p < 0.05) after exercise and at 24 and 48 hours postexercise in both the placebo and the ibuprofen groups with no differences being observed (p > 0.05) between the 2 groups. The results of this study reveal that intake of ibuprofen can decrease muscle soreness induced after eccentric exercise but cannot assist in restoring muscle function.
Adaptive Network-Based Fuzzy Inference approach of estimating of torque for 8∶6 Switched Reluctance Motor

This paper presents a new formulation based on Adaptive Network-Based Fuzzy Inference System(ANFIS) which has been applied to 8∶6 Switched Reluctance Motor(SRM). These developed Adaptive Network-based fuzzy inference system model is a approach to predicting torque of switched reluctance motor which are then tasted in Matlab environment. Error analyzing is also accomplished to verify the average percentage error for ANFIS model. Adaptive Network-Based Fuzzy inference system approach is suitable for use in accurate predicting of torque of 8∶6 configurations SRM.
A measurement study of a massive multi-player online first person shooter game in play-station networks

Massive multi-player online games (MMOGs) have been attracting thousands of millions of participants on the Internet in the past decades. The newly emerging smart phones and game consoles together with PCs have enlarged the player base to an even larger scale. The increasing game traffic may generate significant real-time traffic across different ISP networks. In this paper, we conducted a measurement study of the traffic locality property of a popular online game, Call-of-Duty (CoD), which is a hybrid peer-to-peer (P2P) client/server massive multi-player online first person shooter (MMOFPS) game in the play station network (PSN) over the Internet. To facility our measurement, we designed and implemented a peer crawler over the PSN. Our instrumented crawler applies the principle of the ARP poisoning attack in our justified scenario so that our crawler is able to penetrate the PSN to harvest player's information successfully. We analyzed the measurement results for finer granularity at the autonomous system (AS) level compared with previous measurement studies. Our results show that the sessions in this CoD game are constructed with players' locality in mind. Nevertheless, optimized locality-aware game sessions are yet to be found. Insights obtained from this study may be valuable for the development and deployment of future P2P online gaming systems.
Privacy-Aware Caching in Information-Centric Networking

Information-Centric Networking (ICN) is an emerging networking paradigm where named and routable data (content) is the focal point. Users send explicit requests (interests) which specify content by name, and the network handles routing these interests to some entity capable of satisfying them with the appropriate data response (producer). One key feature of ICN is opportunistic in-network content caching. This property facilitates efficient content distribution by reducing bandwidth consumption, lessening network congestion, and improving the content retrieval latency by users (consumers). Unfortunately, the same feature is also detrimental to privacy of content consumers and producers. Simple to implement, and difficult to detect, timing attacks can exploit ICN routers as “oracles” and allow an adversary to learn whether a nearby consumer recently requested certain content. The attack leverages a timing side channel that relies on router caches and is implemented by requesting a few packets from each piece of content being probed. Similarly, probing attacks that target content producers can be used to discover whether certain content has been recently distributed. After analyzing the scope and feasibility of such attacks, we propose and evaluate some efficient countermeasures that offer quantifiable privacy guarantees while retaining the benefits of ICN.
Effects of methylprednisolone infusions on vital signs in children with headaches.

OBJECTIVES Intravenous methylprednisolone (IVMP) infusions have been associated with adverse cardiovascular effects. Inconsistent monitoring practices in a pediatric hospital led to questions about patient safety and allocation of nursing resources. This study describes vital sign changes in children and monitoring practices related to IVMP. METHODS This retrospective chart review received Institutional Review Board approval. Children aged 5 to 17 years receiving IVMP from January 2006 to January 2009 were included. Seventy-four patients with 94 hospital admissions were evaluated. Data collected included systolic blood pressure, diastolic blood pressure, and heart rate, as well as the time and dosage of IVMP. Frequency of vital sign monitoring as ordered and as performed was described. Interrater reliability was calculated, and descriptive statistics were used in the data analysis. RESULTS At baseline, about half of the patients had vital signs out of normal range for age. After the first dose, vital signs fluctuated, with a majority having greater than 10% changes from baseline as increases, decreases, or both. Time of initial 10% change in vital signs ranged from immediately after the dose to 135.5 hours later. Increased vital sign changes were seen in the older patients and in patients receiving higher doses. Monitoring of vital signs occurred more frequently than was ordered. Only 1 patient had a specific order for monitoring with IVMP. CONCLUSIONS The patients included in this study experienced documented fluctuations in vital signs. A prospective study to evaluate the relationship of IVMP and patient safety will assist in standardizing vital sign monitoring guidelines.
¿Reinfección o reactivación en la tuberculosis pulmonar? Un reto diagnóstico

La recurrencia de la tuberculosis (TB) se convierte en un reto diagnostico debido a que en muchos casos el sistema inmune puede estar alterado como es el caso de las inmunodeficiencias. Existe otro escenario en el cual una cepa distinta de la Mycobacterium tuberculosis puede llegar del exterior y causar nuevamente la enfermedad en el paciente, independiente de su estado inmune, siendo el caso mas frecuente en pacientes inmunocompetentes. La relacion de reinfeccion con el estado inmunosupresor del paciente tiene en cuenta el comportamiento de prevalencia e incidencia de la enfermedad; en el caso del VIH a mayor prevalencia mayor es la incidencia de la tuberculosis, por lo cual se habla de coexistencia de la infeccion. El reto actual alerta a tener una mayor sospecha frente a ciertos casos que merezcan estudiarse de manera profunda a traves de otras tecnicas, buscando si se trata de una reactivacion o de una reinfeccion, teniendo en cuenta el impacto clinico, social y economico que esto genera.
Acute asphyxia affects neutrophil number and function in the rat

Previous studies in adults suggest that various types of physiologic stress appear to decrease phagocytic cell function. Adherence and chemotaxis of, and phagocytosis and bacterial killing by, neonatal neutrophils are altered compared with adult neutrophil function. Stresses encountered by the fetus and neonate, such as asphyxia, were hypothesized to further alter neonatal neutrophil function. To investigate the impact of asphyxia on systemic immunity, we developed a rat model of acute asphyxia and evaluated the effect of asphyxia on neutrophil number and function. Design:Prospective, laboratory study. Setting:Research laboratory. Subjects:Adult female Wistar rats. Interventions:Exposure to CO2 and cold stress. Measurements and Main Results:Arterial blood gas, blood glucose, neutrophil number, neutrophil-mediated, complement-dependent bacterial phagocytosis and killing were determined.After a 20-sec exposure to CO2 and cold stress (dry ice vapors), adult rats developed acute respiratory acidosis (pH 6.89 ± 0.26, Paco2 220 ±183 torr [29.3 ± 24.3 kPa]), and mild hypoxia (60 ± 20 torr [8.0 ± 2.7 kPa]) followed by significant metabolic acidosis (base deficit = −12.0 ± 1.5). Neutrophil number slowly increased and reached statistical significance by 72 hrs (5.0 ± 1.5 × 103/ mm3) compared to controls (2.9 ± 1.6 × 103/mm3) (p = .03). Phagocytosis and killing of group B streptococci by neutrophils isolated immediately after asphyxia were significantly impaired (p = .03), and this decrease in function lasted for 24 hrs after asphyxia (p = .04), as measured by two different in vitro complement and antibody-mediated functional assays. Conclusions:After brief exposure to CO2 and cold stress, rats developed an acute respiratory acidosis and subsequent metabolic acidosis similar to acute asphyxia. Neutrophil number did not increase until 72 hrs after asphyxia. However, neutrophil-mediated phagocytosis and killing of bacteria were immediately impaired. We speculate that asphyxia may increase the risk for sepsis secondary to altered neutrophil function. (Crit Care Med 1993; 21:1929–1934)
Report of the scientific committee.

a study involving line transect surveys and blue whale detections from SOWER vessels operating south of Australia in the summers of 1993 and 1995/96. Pooled data from two ships in the different years were used to estimate a blue whale detection function based on 27 sightings. The only estimate considered by the authors to be reliable is that for 1993, based on 12 sightings within the region bounded 35-45°S and 115-125°E, which was 671 (CV 0.45; 95% CI 279-1,613).
Peer support and young people's health.

The health problems that young people experience are largely related to psychological and behavioural factors. Peer-led initiatives have a positive effect on several factors that influence young people's health. Self-esteem, self-efficacy and locus of control are particularly important to young people's health. The particular strengths of peer support and reciprocal peer support in achieving effective health promotion are described. Practical issues about establishing effective and sustainable peer support initiatives are discussed.
Tick Paralysis Caused by Dermacentor andersoni (Acari: Ixodidae) is a Heritable Trait

ABSTRACT The heritability of the ability to cause paralysis was examined in crosses of virulent and avirulent Dermacentor andersoni (Stiles) (Acari: Ixodidae). Virulence was assessed using hamster bioassay. Paralysis was caused by the virulent parental strain but not by the avirulent parental strain. Four crosses were made: Avirulent ♀ X Avirulent ♂ (AA cross), Virulent ♀ X Virulent ♂ (VV cross), Avirulent ♀ X Virulent ♂ (AV cross), and Virulent ♀ X Avirulent ♂ (VA cross). The proportion of females that produced fertile egg masses was similar among the crosses; however, VV females produced fewer fertile eggs. This was attributed to the long-term laboratory colonization of the virulent strain. All crosses had similar levels of larval and nymphal engorgement and adult eclosion. The ability to cause paralysis was detected in progeny of all crosses except the AA cross. Both heterogeneous crosses caused paralysis, but the virulence was slightly less than for the VV cross. Virulence was similar among the AV and VA crosses, indicating that virulent males were as likely as females to pass the trait to progeny. Time to paralysis was faster for the VV cross compared with the heterogeneous crosses.
The mechanism of pyrimethamine resistance in Plasmodium falciparum

SUMMARY The uptake of radioactive pyrimethamine by a sensitive and a resistant strain of Plasmodium falciparum, the metabolic fate of pyrimethamine inside these parasites and the kinetic properties of dihydrofolate reductase (DHFR) from both strains have been studied. Uptake of the drug was identical in both strains and no metabolite of pyrimethamine was found in either strain. DHFR from the resistant strain was 300 times less sensitive to inhibition by pyrimethamine than the enzyme from the sensitive strain, while the Michaelis constant for dihydrofolate remained unchanged and inhibition was competitive in both cases. Altered properties of plasmodial DHFR are apparently the only mechanism responsible for pyrimethamine resistance in the strain of Plasmodium falciparum studied.
Plasma fibrinogen, global cognitive function, and cerebral small vessel disease: results of a cross-sectional study in community-dwelling Japanese elderly.

OBJECTIVE Recent studies suggest that hemostatic and endothelial factors play a pivotal role in the development of cerebral small vessel disease (SVD). Although plasma fibrinogen is an essential factor in the coagulation cascade, the relationship among fibrinogen, cognitive function, and SVD has not been clarified in community-based Asian populations. Because fibrinogen levels of Asians have been reported to be lower than these of Caucasians, the impact of fibrinogen on the development of SVD or dementia in Asians may be different from that of Caucasians. METHODS We performed a cross-sectional study using MRI to determine the relationships among fibrinogen, cognitive function, and subclinical SVD in community-based Japanese elderly. RESULTS Subjects with raised fibrinogen levels tended to have more lacunes and higher grades of white matter lesions (WMLs). Additionally, an independent association between fibrinogen and WMLs was determined by logistic regression analyses. Subjects with high fibrinogen levels accompanied by high von Willebrand factors or thrombomodulin levels had an increased tendency for the presence of WMLs. The relationship between the mean Mini-Mental State Examination (MMSE) scores and the quartiles of fibrinogen levels was not statistically significant after controlling for age, gender, and WMLs; however, the mean MMSE scores in subjects without WML were related to the tertiles of the fibrinogen levels even after adjusting for conventional risks and high sensitivity C-reactive protein. CONCLUSION The present study suggests that there is a close relationship between fibrinogen levels and subclinical WMLs, which are independent of conventional risk factors and inflammation, in community-based Japanese elderly.
La douceur : critère d’appréciation musicale chez les Tsiganes de Transylvanie

Les Tsiganes de Transylvanie utilisent le terme « douceur » (dulceaţă) pour designer les qualites esthetiques et emotionnelles de la musique. Afin de determiner les parametres (acoustiques et musicaux) associes a la dulceaţă, l’article presente une comparaison de deux versions d’un meme air, l’un joue « sans douceur » et l’autre « avec douceur ». La seconde partie de cet article porte sur le lien entre le concept de douceur et l’idee plus generale de « vivant musical ». La question principale qui est adressee est la suivante : quelles sont les operations mentales et corporelles qui permettent de percevoir la musique comme un « etre intentionnel », ayant la capacite de produire des effets dans le monde, et notamment celui d’emouvoir l’auditeur ?
Surface Externalism Facing the Dark Side of Twin Earth

This account is motivated almost exclusively by its capacity to explain our judgment about XYZ. Since H2O and XYZ do not differ in their superficial characteristics, Twin Earth seems to show that natural kind terms are indexical and that natural kinds are individuated by their causally relevant deep structure. These two claims constitute what I will call the Minimal Putnamian Account (MPA). There appears to be a general consensus that MPA must be true if our judgment about XYZ stems from overarching principles. It thus seems that an independent refutation of MPA and the many proposals that subsume it would suggest that whatever judgments we make about such contrived cases as Twin Earth should be taken as noise and not data to be explained. Sharing in this impression, some have tried to undermine the externalist thesis by criticizing MPA on the basis of imaginative thought experiments that suggest that natural kinds are not individuated by their deep structure (for example, Bach [1987], Mellor
Verzerrte Glaubwürdigkeitsbeurteilung im Schulkontext: Effekt unbewusster Urteilsziele und des Verarbeitungsmodus auf die Glaubwürdigkeitsbeurteilung von Schülerinnen und Schülern

In der vorliegenden Arbeit wurde der Frage nachgegangen, welchen Einfluss die Urteilsziele (wahr vs. erfunden) und der Verarbeitungsmodus (heuristisch vs. systematisch) bei der Beurteilung der Glaubwurdigkeit von SchulerInnen durch LehrerInnen haben. Experiment 1 zeigte, dass das Urteilsziel unabhangig vom Verarbeitungsmodus das Glaubwurdigkeitsurteil in Richtung des Urteilsziels verzerrt. Experiment 2 und 3 zeigten, dass (a) das Urteilsziel die Urteilstendenz beeinflusst und (b) eine systematische Verarbeitung unabhangig vom Urteilsziel die Gute der Urteile erhoht. Die Ergebnisse von Experiment 3 deuten daruber hinaus darauf hin, dass die Antwortlange der Aussagen der SchulerInnen die Urteile der LehrerInnen, die systematisch verarbeiten, beeinflusst. Aufgrund eines neuartigen Designs war es moglich, die Lehrervariablen (Urteilsziel und Verarbeitungsmodus) und die Schulervariable (Antwortlange) in einem Modell abzubilden und die Daten mehrebenenanalytisch auszuwerten. Praktische Implikationen werden diskutiert.
Estimation de retards de signaux GPS en présence de multitrajet

Le gps est un systeme de positionnement par satellite mis au point par les etats-unis dans les annees 60. A l'origine prevu a des fins militaires, ce systeme est present de nos jours dans de multiples applications civiles (radio-navigation aerienne, maritime, positionnement de telephones mobiles). Meme si le systeme rencontre un grand succes de par la diversite de ses capacites, il reste une source d'erreurs (imprecisions du positionnement) non negligeables dues a la presence de trajets secondaires dans certaines configurations ou le signal direct peut se reflechir sur la surface terrestre, des batiments l'objectif de la these est de remedier aux erreurs de positionnement generees par ces multitrajets. L'originalite du travail effectue est de presenter dans un premier temps les techniques de positionnement usuelles dans le contexte sans multitrajet. Les etudes parues sur les problemes d'estimation de retard de signaux gps presentent habituellement les methodes (algorithme, architecture,) de resolution sans les justifier. L'etude s'attache a demontrer que les choix retenus sont issus d'une etude du maximum de vraisemblance et que l'estimateur retenu est donc, en fait, optimal dans le cas sans multitrajet. De plus, nous demontrons les limitations (imprecisions de mesure) de cet estimateur dans le cas avec trajets multiples. Dans un deuxieme temps, nous analysons les proprietes physiques des signaux reflechis grace aux releves experimentaux de nos collaborateurs industriels (thomson-csf detexis), ceci afin de modeliser au mieux les reflexions et de connaitre les lois regissant de tels phenomenes physiques. Finalement, a partir des etudes precedentes et notamment en se basant sur la caracterisation des trajets multiples, l'objectif est de concevoir une methode d'estimation robuste tout aussi bien a l'absence qu'a la presence de ces trajets secondaires. Le choix retenu a ete de se consacrer a une etude du maximum de vraisemblance (dediee au contexte avec multitrajet donc fondee sur un modele avec trajets multiples) pour obtenir l'estimateur optimal dans le contexte etudie. On a montre que cela permet, alors, de conserver une certaine continuite des traitements (habituellement utilises en absence de multitrajet) et donc de prevoir une architecture (brevetee) simple et facile a mettre en oeuvre dans l'ensemble des traitements realises en vue du positionnement en presence de multitrajet
Effect of ultrasound on different quality parameters of functional sirkencubin syrup

Ultrasound is a process studied intensively for different products due to the increasing interest in non-thermal technologies. honey and vinegar and is a functional beverage maintaining health. The aim of this study was to examine the effects of the ultrasound process (pH, titratable acidity, brix, phenolic compounds, flavonoids, antioxidants, total sugar, HMF, sensory evaluation andmicrobiological) on ultrasonic and functional sirkencubin syrup. Ultrasound treatments (26 kHz frequency, 60% amplitude, all samples 200 mL, 80 W power) with different times (2, 5, 8, 10 and 15 minutes) were applied using an ultrasonic processor. The increase in ultrasound time increased most bioactive compounds compared to control samples (untreated). Significant decreases in microbiological load were also recorded. The results of this study show that the ultrasound process can be used as a suitable technique for processing sirkencubin syrup by increasing the bioactive compounds and maintaining safety and quality standards with general acceptance by panelists.
Satisfacción con un destino turístico: Una investigación en Villavicencio (Colombia)

Este articulo presenta una vision de los niveles de satisfaccion derivados de la experiencia del turista y de la vivencia de los habitantes de Villavicencio, en torno al desempeno de la ciudad como un destino turistico. Es un trabajo cuantitativo de analisis correlacional entre variables ordinales, para el cual se tomo como tamano de muestra a 871 personas entre turistas y anfitriones. El objetivo permitio analizar los niveles de satisfaccion de Villavicencio como destino turistico, a partir de las valoraciones realizadas por los turistas y por los residentes. Se destaca que para los turistas internacionales la mayor satisfaccion se manifiesta por la amabilidad de los habitantes. En relacion con los turistas nacionales, la satisfaccion se manifiesta por el uso de espacios naturales. Finalmente, para el caso de los residentes, estos consideran que el desarrollo turistico de la ciudad les genera bajos niveles de satisfaccion.