Miracle-dz/UniFAR-FTUs huggingface dataset:
GAMESS Patch for SGI Origin ( GDDI-O 3 K ) Package

GDDI-O3K is a patch suite against GAMESS, a general ab initio quantum chemistry package maintained by the members of the Gordon research group at Iowa State University, that provides users of SGI Origin with access to the functionality of "processor groups". This functionality is essential for performing analyses based on the fragment molecular orbital method (FMO) 5 and is therefore particularly important for analyzing systems that contain large molecules such as polymers and proteins and/or a large number of small molecules such as the water cluster. Unfortunately, however, it has so far been unavailable on parallel computers that utilize Shared Memory Access (SHMEM) as its low level inter-node communication protocol. Most of our modifications are made to the distributed data interface (DDI) portion of the code. DDI is the message passing layer on which the application part of GAMESS is constructed, and is designed to provide a universally applicable model of processing very large arrays whose patches are distributed among CPU nodes. GAMESS developers set one of their goals as to make it run on any type of Unix computer, from a cluster built from symmetric multi-processor (SMP) enclosures to high-end massively parallel computers. Actually almost all types of UNIX machines have complete access over every functionality of the previous (second) generation of DDI regardless of the type of the communication model: TCP/IP sockets, MPI, LAPI (of IBM), or SHMEM. At the release of the latest (third) generation of DDI, a concept of dynamic grouping of processors was newly incorporated. Under the scheme, processors can be grouped into subsets
PEEP titration guided by transpulmonary pressure: lessons from a negative trial.

Since the first description of the acute respiratory distress syndrome (ARDS) by the landmark paper of Ashbaugh et al . (1), the adequate use of positive end-expiratory pressure (PEEP) has been surrounded by a vivid controversy. This stems from the fact that its beneficial effects on oxygenation by re-aerating collapsed or flooded airspaces, may be counterbalanced by potential adverse effects on hemodynamics and on the risk of increasing lung tissue mechanical stress.
L-Ascorbic acid affect the DNA methytransferase expression in Mouse Embryonic Fibroblasts

Introduction: Induced pluripotent stem cells (iPSCs) can be generated from different source of cells with different efficiencies. Two DNA methyltransferases DNMT1 and DNMT3A have been shown to regulate epigenetically the gene expression involved in cell viability and reprogramming. L-ascorbic acid (L-AA) is a chemical factor that can accelerate reprogramming. Here, we sought to investigate the effect of L-AA on DNMT1 and DNMT3A expressions. Materials and Methods : First, mouse embryonic fibroblasts at passage 3 were cultured in the presence of 10 µg/ml L-AA days for 5 days. Then, DNMT1 and DNMT3A expressions were determined using real-time PCR at days 3 and 5. Results: It was showed that L-AA could enhance DNMT-1 expression which involve in cell viability and decrease the DNMT3A which involve in cell differentiation. Conclusion: The results therefore suggest a new insight into L-AA mechanism impact on reprogramming process.
Comparison of product labelings of two marks of reagent strips for the chemical examination of urine

Background: The urinalysis provides information about renal and urinary diseases, as well as about some extra renal diseases. The chemical examination of urine is done with reagent strips, which allows a quick, simple and economic analyze. Objectives: To compare drug labelings of two marks of reagent strips in urinalysis (Roche Combur10 Test® UX and Bayer Multistix® 10 SG). Material and Method: The principles of pH, protein, glucose, ketone bodies, hemoglobin, bilirubin, urobilinogen, nitrite, specific gravity and leukocytes determinations, as well as the information about possible interferences were compared. Results: There were differences in the detection’s reagents of some parameters, like urobilinogen (The Ehrlich’s reagent present in Multistix is less specific and more propense to analytical interferences than diazonium salt derived of methoxybenzene, used by Roche strip); the differences in the reagents used for nitrite, protein, glucose, bilirubin and hemoglobin determinations were relatively subtle. Discussion: There was diversity of information about the potential interferences, which could be justified (at least partially) by differences in the reagents. Differences in the information about interferences had been detected between Spanish and Portuguese versions in the same product labeling, like the omission of some interferences in the product labeling in Portuguese. Great disparity in the reaction’s intensity and its expression in crosses were observed (e.g. for glucose), and it could lead to misunderstanding in the interpretation of laboratorial findings. Conclusion: These data reinforce the importance of standardizations in the urinalysis. Urinalysis
Predicting prognosis in colorectal liver metastases.

Liver surgeons treating colorectal liver metastases (CRLM) are on the verge of fascinating times. On one hand, there is a trend towards minimally invasive, or percutaneous, approaches of liver treatment, whereas on the other hand reports on maximally invasive surgery have come out that claim survival benefit for CRLM patients if treated aggressively. In order to choose between these different treatment philosophies, the surgeon, and equally importantly the patient, need tools. Tools that will tell whether the proposed treatment option will indeed be of benefit for the patient sitting in clinic in front of you.
Electronic Health Self-Management Interventions for Patients With Chronic Kidney Disease: Systematic Review of Quantitative and Qualitative Evidence

Background Chronic kidney disease (CKD) poses a major challenge to public health. In CKD patients, adequate disease self-management has been shown to improve both proximal and distal outcomes. Currently, electronic health (eHealth) interventions are increasingly used to optimize patients’ self-management skills. Objective This study aimed to systematically review the existing evidence regarding the implementation and effectiveness of eHealth self-management interventions for patients with CKD. Methods Following a search in 8 databases (up to November 2017), quantitative and qualitative data on process and effect outcomes were extracted from relevant studies. Quality was appraised using the Crowe Critical Appraisal Tool; narrative synthesis was performed to analyze the data extracted. Results Of the 3307 articles retrieved, 24 (comprising 23 studies) were included in this review; of these, almost half were appraised to be of low to moderate quality. There was considerable heterogeneity in the types of interventions used and the outcomes measured. A total of 10 effect and 9 process outcome indicators were identified. The most frequently reported effect outcome indicators were specific laboratory tests and blood pressure (BP), whereas satisfaction was the most frequently reported process outcome indicator. Positive effects were found for proximal outcomes (eg, BP control and medication adherence), and mixed effects were found for more distal outcomes (eg, quality of life). High feasibility, usability, and acceptability of and satisfaction with eHealth self-management interventions were reported. The determinant ability of health care professionals to monitor and, if necessary, anticipate on patient measurements online was mostly cited to influence patients’ adherence to interventions. Conclusions eHealth self-management interventions have the potential to improve disease management and health outcomes. To broaden the evidence base and facilitate intervention upscaling, more detailed descriptions and thorough analysis of the intervention components used are required. In addition, our review reveals that outcomes closely related to the scope and duration of the intervention implemented are most likely to be impacted. For instance, if a 4-week Web-based training to optimize disease management skills is implemented, the outcome perceived control would more likely be affected than kidney function. Although this seems obvious, most studies evaluate only distal outcomes and thereby fail to capture intervention effects that might contribute to long-term health improvement. We advise future researchers to carefully consider their choice of outcomes based on their sensitivity for change. In this way, we ensure that relevant effects are captured and legitimate conclusions are drawn.
EXPATRIATE AND SPOUSAL ADJUSTMENT IN THE AIR FORCE 2 Overseas Assignments : Expatriate and Spousal Adjustment in the U . S . Air Force

Overseas Assignments: Expatriate and Spousal Adjustment in the U.S. Air Force. Andrew R Hayes. Master of Arts in Industrial/Organizational Psychology. Minnesota State University, Mankato. Mankato, MN. 2014. The present study examined the relationship between cultural intelligence (CQ), expatriate and spousal/partner adjustment, and satisfaction with an overseas military assignment at a NATO Air Force base. Cultural Intelligence was measured using the Cultural Intelligence Scale (CQS) by Ang, et al. (2007). Expatriate adjustment was measured using the Expatriate Adjustment scale by Black & Stephens (1989). Spouse/partner adjustment was measured using the Spouse Adjustment scale by Black & Stephens (1989). Satisfaction was measured with a 5-item scale developed by the researchers. All data was collected via an online survey. There were 178 Airmen respondents and 89 spouse/partner respondents. Significant, positive relationships were found between cultural intelligence and adjustment. A regression analysis indicated that motivational CQ was the strongest driver of adjustment for both spouses/partners and Airmen. Significant, positive relationships were found between adjustment and satisfaction with the overall assignment, and more specifically, satisfaction with life on base. Regression analysis indicated that general adjustment predicted overall satisfaction for spouses/partners and Airmen. Interaction adjustment predicted base satisfaction for spouses/partners. Both general and work adjustment predicted base satisfaction for Airmen. In the Airmen sample, support was found for adjustment as a mediator between CQ and overall satisfaction, but this support was not found in the partner sample. Overall, CQ was a significant predictor of adjustment, and adjustment was a significant predictor of satisfaction. There was partial support for adjustment as a mediator between CQ and satisfaction. EXPATRIATE AND SPOUSAL ADJUSTMENT IN THE AIR FORCE 6
Casing Vibration Fault Diagnosis Based on Variational Mode Decomposition, Local Linear Embedding, and Support Vector Machine

To diagnose mechanical faults of rotor-bearing-casing system by analyzing its casing vibration signal, this paper proposes a training procedure of a fault classifier based on variational mode decomposition (VMD), local linear embedding (LLE), and support vector machine (SVM). VMD is used first to decompose the casing signal into several modes, which are subsignals usually modulated by fault frequencies. Vibrational features are extracted from both VMD subsignals and the original one. LLE is employed here to reduce the dimensionality of these extracted features and make the samples more separable. Then low-dimensional data sets are used to train the multiclass SVM whose accuracy is tested by classifying the test samples. When the parameters of LLE and SVM are well optimized, this proposed method performs well on experimental data, showing its capacity of diagnosing casing vibration faults.
Method for estimating in situ chemo-lithotrophic ammonium oxidation using carbon monoxide oxidation

A sensitive new method for estimating chemolithotrophic ammonium oxidation (nitrification) has been developed. Carbon monoxide oxidation, using ',CO, is measured with and without the addition of 100 mg I-' of N-Serve, a specific nitrification inhibitor. The N-Serve sensitive CO oxidation can be related to the rate of ammonium oxidation by chemohthotrophic ammonium oxidizers. Methane oxidation, using ',CH,, is also measured to determine the potential for ammonium and CO oxidation by methane oxidizer populations. This method was used to examine pure cultures of ammoniun~ and methane oxidizers, as well as organisms in soil, 2 freshwater lakes, and estuarine waters. Ammonium oxidizers were found to be responsible for 28 to 97 % of the CO oxidation in the environmental samples examined. Ammonium and methane oxidizers were found to have widely different CH, oxidation to CO oxidation ratios, allowing distinction between environmental types where ammonium oxidizers achieve dominance.
“ Llama ” : Confidence 99 . 8 “ Llama ” : Confidence 71 . 1 Feature-Importance Map Feature-Importance Map Feature-Importance Map “ Monarch ” : Confidence 99 . 9 “ Monarch ” : Confidence

In order for machine learning to be trusted in many applications, it is critical to be able to reliably explain why the machine learning algorithm makes certain predictions. For this reason, a variety of methods have been developed recently to interpret neural network predictions by providing, for example, feature importance maps. For both scientific robustness and security reasons, it is important to know to what extent can the interpretations be altered by small systematic perturbations to the input data, which might be generated by adversaries or by measurement biases. In this paper, we demonstrate how to generate adversarial perturbations that produce perceptively indistinguishable inputs that are assigned the same predicted label, yet have very different interpretations. We systematically characterize the robustness of interpretations generated by several widely-used feature importance interpretation methods (feature importance maps, integrated gradients, and DeepLIFT) on ImageNet and CIFAR-10. In all cases, our experiments show that systematic perturbations can lead to dramatically different interpretations without changing the label. We extend these results to show that interpretations based on exemplars (e.g. influence functions) are similarly susceptible to adversarial attack. Our analysis of the geometry of the Hessian matrix gives insight on why robustness is a general challenge to current interpretation approaches.
The optical counterpart to IGR J06074+2205: a Be/X-ray binary showing disc loss and V/R variability

Context. Current X-ray missions are regularly discovering new X/γ-ray sources, so identifying the counterparts of these high-energy sources at other wavelengths is important for determining their nature. In particular, optical observations are crucial in the study of X-ray binary populations in our Galaxy. Aims. The main goal of this work is to determine the properties of the optical counterpart to the INTEGRAL source IGR J06074+2205 and study its long-term optical variability. Although its nature as a high-mass X-ray binary has been suggested, little is known about its physical parameters. Methods. We have been monitoring IGR J06074+2205 since 2006 in the optical band. We present optical photometric BVRI and spectroscopic observations covering the wavelength band 4000−7000 A. The blue spectra allow us to determine the spectral type and luminosity class of the optical companion and the red spectra, together with the photometric magnitudes, were used to derive the colour excess E(B − V) and estimate the distance. Results. We have carried out the first detailed optical study of the massive component in the high-mass X-ray binary IGR J06074+2205. We find that the optical counterpart to IGR J06074+2205 is a V = 12.3 B0.5Ve star located at a distance of ∼4.5 kpc. Monitoring of the Hα line reveals V/R variability and an overall decline in its equivalent width. The Hα line has been seen to revert from an emission to an absorption profile. We attribute this variability to global changes in the structure of the Be star’s circumstellar disc that eventually led to the complete loss of the disc. The density perturbation that gives rise to the V/R variability vanishes when the disc becomes too small.
Outcomes of Fast-Track Multidisciplinary Care of Hip Fractures in Veterans: A Geriatric Hip Fracture Program Report

Background Hip fractures are a significant cause of morbidity and mortality in the elderly. Fast-track multidisciplinary co-management of these patients, rapid preoperative optimization, early surgery, and expeditious rehabilitation may minimize morbidity and mortality. In this study, we evaluated outcomes of fixation of hip fractures in the elderly patients managed by Geriatric Hip Fracture Program at a military hospital in India. Methods A total of 114 patients above 60 years of age with hip fractures were enrolled. They were comanaged by a team of specialists and fast-tracked to surgery. Independent ambulation with support of a walker was achieved before discharge to home. Patients were followed up for 1 year. Results The average age of the 114 patients was 77 years; 24 patients were octogenarian. Eighty-four percent of injuries were due to a domestic fall. Hypertension (41%) and diabetes (22%) were the most common comorbidities. All patients were optimized before surgery. The average delay from injury to admission was 1.7 days (range, 0 to 14 days) and that from admission to surgery was 1.8 days (range, 0 to 19 days). Hence, the average time from injury to surgery was 3.5 days. The length of stay in hospital was, as per rehabilitative milestones achieved, 2 to 5 days in 40% of the patients and 6 to 15 days in 60% of the patients. At 1 year after surgery, 95 patients were independently ambulant (56 patients with support and 39 patients without support). Twenty-three percent of the patients had postoperative complications and eight patients died (7.7%) at 1-year follow-up; 11 patients were lost to follow-up. Conclusions Elderly hip fracture has a high risk of mortality (14%–58%). Thus, expeditious surgery within 24 hours of admission has been advocated in the Western literature to minimize mortality. Mortality rate at 1 year after surgery remains at 10% to 24%. In our study, even with aggressive co-management, the average delay to hip fracture fixation was more than 3 days; however, the 1-year mortality was relatively low (7.7%). This indicates the importance of preoperative optimization and postoperative rehabilitation for independent ambulation and mortality reduction in the elderly population.
Treatment of inflammatory pain – an interdisciplinary problem from the perspective of a rheumatologist, neurologist, physiotherapist, pain specialist and clinical pharmacologist

The article discusses inflammatory pain in an interdisciplinary way, including opinions on methods of treatment of disease entities in which a component of inflammatory pain appears by various specialists: a rheumatologist, neurologist, physiotherapist, clinical pharmacologist and pain medicine specialist. The pathomechanism of inflammatory pain, which determines the choice and effectiveness of therapy, has been widely discussed. The most common type of inflammatory pain is pain in the organ of the movement, which also dominates as the most frequent reason for experiencing pain and the cause of disability of patients, which is why this topic was discussed the most widely.
Genetic Diversity of QPM and Provit-A Maize Genotypes Based on SSRs (Simple Sequence Repeats) Markers

Information on genetic diversity of QPM and Provit-A maize germplasm is important to support breeding program, in order to form a high yielding maize hybrid. Simple sequence repeats (SSR) have been extensively utilized as genetic markers to study the genetic diversity, cultivar identification, and gene mapping. The objectives of this research were to investigate the genetic diversity and to obtain information the genetic relationship among 20 maize accessions using 29 SSRs. The research was carried out at the Moleculer Biology Laboratory of Indonesian Cereals Research Institute (ICERI) in Maros, South Sulawesi. Twenty nine polymorphic primers that covered the 10 maize chromosomes were used to fingerprint the genotype of the lines, detecting 83 allels, with an average allel number of 3 allels per locus, ranging from 2 to 6 alleles per locus. The results indicated that polymorphism information content (PIC) ranged from 0.10 (nc133 and phi072) to 0.74 (phi064) with the average of 0.45. Genetic distance based on genetic similarity estimate ranged from 0.39 to 0.92. The high level of PIC values and wide genetic distances indicated the large variability among maize germplasm. Cluster analysis divided the 20 maize accessions into three groups. Coefficient cofenetic value (r) was 0.85 indicated a good fit based on the genetic similarity value. As many as 30 inbred heterotic recombinants were derived by incorporating 20 QPM and Provit-A with genetic distance of ≤0.65. The SSRs proved to be reliable and is practical technique for revealing the relationship among specialty maize genotypes.
Spirals and Cycles of Biological Systems via Extended Rosenzweig-MacArthur Model with Ratio-dependent Functional Response

This paper investigates stable proper nodes, stable spiral sinks and stable ω−limit cycles of Extended Rosenzweig-MacAthur Model, which incorporates ratio-dependent functional response on predation mechanism. The ultimate boundedness condition has been used to predict extinction, co-existence, and exponential convergence scenarios of the model. The Poincare-Bendixson results guarantee existence of periodic cycles of the models. The system degenerate from stable spiral sinks to stable ω−limit cycles as control parameter varies. Numerical simulations are provided to support the validity of theoretical findings.
APARICIÓN TEMPRANA DEL PATRÓN DE DOLOR CRÓNICO EN PACIENTES MUSCULOESQUELÉTICOS SUBAGUDOS

El patrón de dolor crónico implica altos niveles de emociones negativas, dolor y discapacidad percibida. Pocos estudios han evaluado el patrón de aparición del dolor crónico y éste era nuestro objetivo. Método: fueron evaluados 146 participantes con 4 semanas la Baja Laboral por enfermedades musculoesqueléticas (DsMS) y 95 con artritis reumatoide (AR) mediante los siguientes instrumentos: el Cuestionario de Tristeza y Depresión (CTD), el Inventario de Situaciones y Respuestas de Ansiedad–forma breve-. (ISRA-B), Cuestionario de Evaluación de Salud (HAQ), una escala analógica visual para la intensidad del dolor y una escala tipo Likert para la frecuencia del dolor. Los análisis (descriptivos y bivariados) incluyeron una comparación de las puntuaciones de las pruebas entre los pacientes con baja laboral por EM en comparación con los pacientes con AR. Resultados: Los pacientes con Baja Laboral por enfermedades musculoesqueléticas y los pacientes con AR informaron de una percepción similarde su discapacidad, según el HAQ. Pacientes con Baja Laboral por enfermedades musculoesqueléticas informaron mayor frecuencia percibida y más intensidad de dolor que los pacientes con AR. En relación a las emociones negativas, ambos grupos presentaron niveles altos y similares, con algunos niveles más pobres de los pacientes con AR en comparación con Pacientes con Baja Laboral por enfermedades musculoesqueléticas para la ansiedad cognitiva, la ansiedad de evaluación y la de la vida cotidiana (en ISRA-B). Las puntuaciones en depresión presentan los mismos niveles en ambos grupos de pacientes. Conclusión. Nuestro estudio muestra que los pacientes con dolor subagudo/discapacidad y dolor crónico/discapacidad reportan un patrón muy similar para las emociones negativas y la percepción del dolor y la discapacidad, lo que sugiere que estos factores aparecen en una etapa temprana y favorecen, por tanto, la transición de dolor agudo a crónico/discapacidad.