Miracle-dz/UniFAR-FTUs huggingface dataset:
The Awareness of Folic Acid Supplements among Women of Childbearing Age in King Abdulaziz University Hospital, Jeedah - Saudi Arabia

Background: This study aimed to assess the awareness of the importance of folic acid in preventing neural tube defects (the timing of folic acid supplementation and the right doses) in Jeddah the western region of Saudi Arabia. Method: A sample of 501 married women in the reproductive age (19-45 years) who visited the outpatients clinics at King Abdulaziz University Hospital between August and October/2015 were asked to participate in a survey study targeting the awareness and the use of folic acid before and during pregnancy. First step was collecting participants' responds on a range of questions related to socio-demographic and medical characteristics. Then in second step they were provided with questions related to their awareness before and after reading the distributed intervention brochure. Results: Of the 501 Participants, 317 (63.3%) were Saudies, many were above 30 years of age (55.1%), 460 (91.8%) heard about folic acid and 429 (85.6%) have taken it. However, only 169 (33.7%) knew that it must be given during preconception and as early as the 1st 12 weeks of gestation. A significant difference was found before and after reading the brochure in participants' knowledge about the benefits of folic acid in preventing neural tubal defect, the critical time of administration, and the right doses (P<0.000, P<0.000, P<0.000) respectively. University education was the strongest predictor to have the right information with significant difference (P<0.000). 279 (71.2%) of the participants reported the medical staff as to be their main source of information Conclusion: The health care professionals and media need to increase women awareness about the importance of taking folic acid supplementation in the proper time to reduce the risk of neural tube defects.
Factors associated with zidovudine substitution in HIV/AIDS patients attending Badung Hospital, Bali, Indonesia between 2006-2014

Background: Zidovudine (AZT) is the most commonly used drug in first line antiretroviral therapy (ART) in Indonesia; however, substitution due to its side effect is common. The majority of HIV positive patients in Badung Hospital Bali are treated with AZT yet no longitudinal studies in Bali have investigated the number of substitutions or the factors associated with it. Methods: A retrospective cohort study of HIV positive persons aged >15 years, receiving AZT between 1 st January 2006 – 31st August 2014 was conducted. Persons were included from their date of starting AZT. Cox proportional hazard models were applied to estimate the risk and time to substitution. Substitution was defined as single drug change due to side effects and initiating another drug of the same class. Results: During our study 260 patients started AZT, of which 77 (29.6%) experienced substitution. The risk of substitution was 19 per 100 person years. Of those 77, the median time to AZT substitution was 69 days (IQR 25-178). Factors significantly associated with an increased risk of AZT substitution included women (HR 1.79; 95% CI 1.09-2.94), having low hemoglobin levels <10g% (HR 2.72; 95% CI 1.02-7.21), clinical stage III and IV (HR 3.53; 95% CI 1.26-6.19) at the time of starting AZT, and starting ART after 2012 (HR 3.83; 95% CI 2.19-6.70). Conclusions: Present study identified individuals that may be at a high risk of AZT substitution who should be monitored more closely or consideration given to initiating them on another treatment regimen.
Sound field synthesis based on superposition of multipoles comprising focused monopole sources

: We propose a method to create a directional sound source in front of a linear loudspeaker array. The method creates clusters of focused sources to form multipoles by using a linear loudspeaker array and superposes the multipoles to synthesize a directivity pattern. We also derive an eﬃcient multipole structure in which adjacent lower order multipoles are overlapped. The structure reduces the number of focused sources, thereby reducing the algorithmic complexity needed to create them. To further reduce complexity, we also derive a time domain implementation of the proposed method. To mitigate degradation in the reproduced directivity due to superposition of the inaccurate sound ﬁelds of focused sources, a fractional delay interpolation is applied. Computer simulation results indicate that the proposed method based on superposition of up to the third order multipoles creates a directional sound source at signiﬁcantly lower complexity than a conventional method.
Clast transport history influences Schmidt hammer rebound values

The Schmidt hammer (SH) is widely used in geomorphology for relative‐ and calibrated‐exposure age dating surfaces and deposits within landforms. This study employs a laboratory‐based methodology to assess the effects of surface roughness, clast roundness, and clast volume on SH rebound values (R‐values) by analyzing samples from three modern depositional environments (i.e. river, alluvial fan, talus). Each environment contains clasts of Torlesse supergroup greywacke sandstones with distinct roundness and micro‐scale roughness characteristics. Roundness, surface roughness, and clast volume were all found to influence R‐values significantly. The R‐values from different deposit types are statistically significant and could potentially create an apparent age divergence of several thousand years for samples with the same exposure‐age. © 2020 John Wiley & Sons, Ltd.
ACCESSING HIGHER EDUCATION AFTER 23 YEARS OLD: OPPORTUNITIES AND MOTIVATIONS

Abstract This article reports a case study in a Portuguese public institution of higher education that aimed at characterizing the profile of the students that access the institution, through examinations for candidates aged 23 or over (M23 Access), focusing on the motivations for their entry and on their perspective of this type of access to higher education. This mixed method study used a questionnaire, answered by 180 former students. Acquisition of new knowledge, personal valorization and a professional change are among the most important reasons to access higher education. While analyzing the results, we are also able to discern the importance of implementing educational policies for adults, which, in the Portuguese case and regarding the promotion of learning opportunities for all, are still few and poorly disseminated.
La importancia de la inteligencia emocional del profesorado en la misión educativa: impacto en el aula y recomendaciones de buenas prácticas para su entrenamiento

Las aulas son contextos donde las emociones forman parte del proceso de aprendizaje. Las habilidades emocionales del docente son claves para fomentar ambientes de aprendizaje positivo. Pero ? Como ayudan al profesorado y al alumnado? , ? Como podemos mejorar las habilidades emocionales? , ? Que programas existen? Este trabajo aporta evidencias y recomendaciones utiles para el desarrollo de programas de inteligencia emocional con docentes.
Melatonin and cardiac pathophysiology

Melatonin, an indole produced in several organs but most notably in the pineal gland, has a variety of effects that influence cardiac pathophysiology. Herein, we summarize the findings that illustrate the ability of melatonin to attenuate the severity of hypertension, limit myocardial damage, improve the function of the ischemic-reperfused heart, protect the heart from the toxicity of anthracycline drugs and from an immunosuppressant drug (cyclosporine A), and reduce cardiac hypertrophy and the associated pathophysiology caused by hyperthyroidism. The protective actions of melatonin at the level of the heart probably involve membrane melatonin receptors that exist on cardiomyocytes, in addition functions of melatonin as an antioxidant that are not receptor mediated. Whereas studies to date have been performed primarily in experimental animals, the uncommonly low toxicity of melatonin warrants tests of its utility in humans in cases of cardiac pathophysiology.
Mechanical vulnerability of the L3-L4 spinal segment after fusion surgery utilizing dynamic stress analysis

Introduction: Pedicle screw-based spine fusion has been employed as a felicitous approach for treatment of degenerative lumbar spinal diseases. Although the pedicle screw designs and fixation techniques have progressed, many clinical studies have reported the adjacent segment degeneration (ASD) and several other adverse effects after surgery. In the case of fixation techniques, the use of semi-rigid rods such as Polyarylether ether ketone (PEEK) rods can be an appropriate substitute for rigid fusion instrumentation. However, the biomechanical effects of using viscoelastic PEEK rods for use in clinical studies are still unclear. Materials and Methods: In this study, the effects of using two pedicle screw-based stabilization systems, i.e. viscoelastic PEEK rods and elastic Titanium rods, on the stress distribution in the l3-l4 intervertebral disc and the surrounding osseous tissue were investigated. An L1-L5 lumbar region was modeled. Subsequently, a mild degenerative disc disease was simulated in the L3-L4 lumbar level. Next, an axial cyclic torque was applied to the model. Results: The results showed that, at the end of the loading cycle, the maximum von-Mises stress in the l3-l4 intervertebral disc as well as the overall value of stress in the surrounding osseous tissue were slightly greater in the viscoelastic model as compared to the elastic one. Nonetheless, the stress distribution contours and the location of maximum stress were different in the two models. Conclusion: It can be postulated that the vulnerable areas of lumbar bone are different in two models.
Healthcare workers’ perceptions of organisational culture and the impact on the delivery of compassionate quality care

This paper explores the qualitative outcomes as part of a larger feasibility study which was developed to test a Cultural Health Check toolkit designed to assist healthcare workers and organisations in the provision of safe, dignified and compassionate quality care for older people. For the qualitative part of this project, 11 healthcare workers agreed to participate in a one-to-one semi-structured interview. The primary aim of the research was to identify the experiences of staff in relation to the different factors they feel contribute to the culture of the organisation. These data were analysed using Attride-Stirling thematic analysis. The data were coded and four global themes were evident: professional practice, support, workforce and service delivery. Professional practice included organisational themes of quality, communication and collaboration and how these impact on a health worker’s ability to carry out their role and the impact on the delivery of compassionate quality care. Support included organisation themes of personal and professional development, and facilitation by leaders and managers to access the available support. Workforce centred on the importance of having adequate levels of all staffing groups to be able to deliver safe, quality person-centred care and services. Service delivery identified the organisational themes of care, person-centred care and communication where staff have the desire, determination and enthusiasm to deliver safe, high quality compassionate person-centred care and services. These themes are key in the impact analysis relating to the delivery of compassionate quality care.
On the Increment of the Bandwidth of Mushroom-Type EBG Structures With Glide Symmetry

Mushroom-type electromagnetic bandgap (EBG) structures are known to operate as high-impedance surfaces at low-frequency bands. They are broadly used in the microwave regime. However, one of the main drawbacks of mushroom-type EBG structures is their narrow bandwidth. In this article, we propose a mushroom-type EBG structure with glide-symmetric edge vias to increase the operational bandwidth. This bandwidth increment is explained by the physical insight provided by an equivalent circuit model of the structure as well as the description of the field behavior. Simulation and measurement results show an improvement of approximately 67% over the case without glide symmetry in the structure. We conclude that applying glide symmetry to the mushroom-type EBG structures can improve their bandwidth without adding additional manufacturing costs.
“Swimming against the tide”: conditional discharge from medium secure care

Purpose The purpose of this paper is to explore the experiences of mentally disordered offenders (MDOs) conditionally discharged from secure hospitals on a restrictive Section of the Mental Health Act (Section 37/41). Design/methodology/approach Data were derived from seven semi-structured interviews from three forensic community teams. Findings Thematic analysis identified seven predominant themes: (1) the uncertainty of the discharge timeframe; (2) fear of jeopardising discharge; (3) progress; (4) engagement with community life; (5) barriers to social engagement; (6) evolving identity and (7) someone to turn to. Findings are discussed in relation to the recovery model and the good lives model. Practical implications The findings highlight the importance of fostering trust between MDOs and their care teams to encourage help-seeking. They also suggest that resources should be sequenced appropriately throughout the discharge process, to match the “window of engagement” and maximize impact and effectiveness. Originality/value This research gained rarely obtained first-hand perspectives from MDOs, with the findings contributing to a more effective evaluation of the discharge pathway.
Hubungan Antara Kualitas dan Intensitas Dzikir Dengan Kelapangdadaan Mahasiswa

The following article constitutes the result of research. This research aims to describe corelation the quality and intensity of dzikr and the tolerant attitudes of regular students and boarding school students. The indicators that used in this research is the scale of tolerant attitudes, that of dzikr quality and intencity. The subject of the research is 109 students. This research revealed that there is positive corelation dzikr quality and the tolerant attitudes of regular students and boarding school students. The contribution of dzikr quality to the-tolerant attitude is 41.5 %. There is a negative corelation dzikr intencity and the tolerant attitude of regular students and boarding school students.
Metodologia de avaliação laboratorial do sêmen congelado bovino

Several methods of laboratory analysis of frozen bovine semen have been developed, however the correlation between sperm parameters and fertility rates in vivo are still variable. Among the major sperm analysis we can found: sperm motion and morphology, separation tests and morphofunctional analysis by fluorescence microscopy or flow cytometry. Although no evaluation technique taken alone provide enough sensitivity for the fertility determination, the combination of many methods has added greater precision to estimate the potential fertility of frozen bovine semen samples. The objective of this review will be describe the methods of laboratory analysis of frozen bovine semen.
Commitment to the Teacher’s Loyalty as a Customer

Customer loyalty is the major importance in maintaining customer and to attract new customer at SMEs. It becomes also the important attention for Koperasi Sejahtera Bersama. In maintaining customer, it is needed Customer Relationship Management and Customer Commitment, especially for the customer who comes from school, in this case, is Teacher. Remember that the teacher can give a good recommendation to students, parents and even co-workers. Reviewing problem phenomenon, so the aim of this study is to review the correlation of Customer Relationship Management and Commitment to the teacher's loyalty as a customer. This quantitative research uses 95 respondents from a customer of Koperasi Sejahtera Bersama that mostly are Teachers, through hypothesis test. The research finding is found that there is a positive correlation between Customer Relationship Management and Commitment on Loyalty. Commitment has a stronger bond on loyalty than Customer Relationship Management. The difference seems on there is no significant correlation between Customer Relationship Management with Loyalty, in which in the previous research those correlations are found very closely. This research result explains the importance of Relationship Management on Teacher as a customer, in order to improve loyalty bonding. It is expected that those loyalties provide the impact on Teacher's recommendation to their environment Keywords—customer relationship management; commitment;
The role of Toll-like Receptor 4 in diabetic foot ulceration

Introduction Diabetes Mellitus has reached epidemic proportions. Foot ulceration is a multifactorial complication of diabetes associated with marked morbidity and mortality. Innate-immune Toll-like receptor 4 (TLR4) mediated inflammation has been implicated in the systemic pathogenesis of diabetes and may contribute to impairment of wound healing. This thesis investigates the effect of high glucose and hypoxic conditions on TLR4 activation and signalling in vitro and in vivo. Method Human skin biopsies were stained for H&E and TLR4. Fibroblasts cultured at physiological glucose concentration (5.5mM) were exposed to pathological glucose concentrations (25mM), with duplicate samples placed in a hypoxia chamber. The effect of TLR4 and its signalling pathway was assessed through specific inhibitors. Diabetes was induced in wild-type (WT) and TLR4 knock-out C57BL/6 mice by intra-peritoneal injection of low-dose streptozocin. Hindlimb ischaemia was induced by femoral artery ligation four weeks post- streptozocin, and a full thickness skin wound inflicted below the knee. Wound healing was assessed via digital planimetry at days 3, 7 and 14 post surgery. Results Diabetic-ischaemic ulcers demonstrated greater inflammatory cell infiltration (p=0.0001) and TLR4 expression (p=0.038). Hypoxic and high glucose (25mM), conditions led to an increase in TLR4 protein expression, apoptosis and IL-6 release. Inhibition with MyD88 inhibitory-peptide, TLR4 neutralising-antibody and specific TLR4 antagonist ameliorated the effects of high glucose and ischaemia (p<0.05). In vivo, wound healing was significantly impaired in the diabetic-ischaemic group at day 14 (p<0.05). Diabetic-ischaemic wounds in TLR4 KO mice exhibited significantly improved healing rates compared to those in WT mice at all time points. Conclusion Diabetic-ischaemic ulceration is associated with increased cellular inflammation and TLR4 expression. Hypoxia stimulates up-regulation of TLR4 protein expression and this effect is exaggerated by hyperglycaemia. Inhibition of TLR4 significantly reduced TLR4 protein expression, apoptosis and IL-6 release, suggesting a protective effect. In TLR4 KO mice, there is a significant improvement in the healing of diabetic-ischaemic wounds compared to WT. We propose a synergistic effect between hypoxia and hyperglycaemia impairing wound healing exists, through TLR4-mediated inflammation.
User Association for Load Balance in Heterogeneous Networks With Limited CSI Feedback

Conventional user association (UA) scheme based on max-signal-to-interference-plus-noise-ratio (max-SINR) criterion results in a severe load imbalance problem in heterogeneous networks (HetNets), leading to substantial performance loss. The state-of-the-art solutions to load imbalance mostly formulate the UA problem as a complicated global optimization that requires full channel state information (CSI) between every base station-user pair. Therefore, searching for optimal UA scheme imposes extremely high complexity as well as signaling overhead, and thus limits its practical applications. In this letter, the UA problem is reformulated as a local optimization at the macro base station, and is solved with only limited CSI feedback, where each user reports the synchronization signal powers instead of full CSI. After that, a low-complexity successive offloading (SO) scheme is derived. Numerical simulations demonstrate that the SO scheme achieves near optimal performance with much lower complexity.
Assessment of streamflow decrease due to climate vs. human influence in a semiarid area

Abstract. This paper uses the Budyko method to investigate mean annual streamflow changes, due to climate variation and human influence, in the important Karkheh River Basin in western Iran. To validate the results, hydrological modelling (HBV model) and Landsat 5 Thematic Mapper (TM) images were used for the study period between 1980 and 2012. The recently developed DBEST (Detecting Breakpoints and Estimating Segments in Trend) method identified an abrupt negative change in the streamflow trend in 1994–5. The results show that the observed streamflow decrease in the Karkheh River is associated with both climate variation and human influence. The combination of increased irrigated area (from 9 to 19 % of the total basin area), reduction of forests (from 11 to 3 %), and decreasing annual precipitation has significantly reduced streamflow in the basin. Moreover, the results show that the streamflow reduction in the Karkheh Basin is more sensitive to the change in precipitation than temperature.
Integration geschlechtsspezifischer Inhalte in die Lehre der Charité - Universitätsmedizin Berlin [Integration of gender-specific contents into the medical education at the Charité - Universitätsmedizin Berlin]

Introduction: Knowledge derived from gender specific research is more and more integrated into the medical education. In Germany this process is developing with a certain delay compared to other Anglo-Saxon or Scandinavian countries. Our survey examines for the first time to what extend gender specific aspects have been integrated into the medical education at the Charite Universitaetsmedizin Berlin. Material and Methods: Topics like gender specific learning objectives and their implementation in the own field were evaluated by means of a standardized questionnaire, differentiated for professors, medical teachers and course coordinators as well as for sex in qualitative and quantitative categories. Results: 30 different fields of medicine took part in this study and revealed a number of important topics with gender specific differences. These contents are integrated into the medical education with relatively simple methods by 70% of the participating professors and medical teachers. In general there is only little interest in spending time for further qualification or the development of a curriculum for the field of gender medicine. Female participants of this study were significantly more interested in gender medicine aspects (p=0,017 development of the medical curriculum). Conclusion: This study underlines the need for official learning objectives containing gender differences during the medical education at the Charite Berlin. A great number of the teaching staff reveals a positive attitude towards these contents and integrates a lot of them. These efforts should be supported by more gender specific teaching material and personal investment into the curricular development.