Miracle-dz/UniFAR-FTUs huggingface dataset:
Functional Gene Expression Differentiation of the Notch Signaling Pathway in Female Reproductive Tract Tissues—A Comprehensive Review With Analysis

The Notch pathway involves evolutionarily conserved signaling regulating the development of the female tract organs such as breast, ovary, cervix, and uterine endometrium. A great number of studies revealed Notch aberrancies in association with their carcinogenesis and disease progression, the management of which is still challenging. The present study is a comprehensive review of the available literature on Notch signaling during the normal development and carcinogenesis of the female tract organs. The review has been enriched with our analyses of the TCGA data including breast, cervical, ovarian, and endometrial carcinomas concerning the effects of Notch signaling at two levels: the core components and downstream effectors, hence filling the lack of global overview of Notch-driven carcinogenesis and disease progression. Phenotype heterogeneity regarding Notch signaling was projected in two uniform manifold approximation and projection algorithm dimensions, preceded by the principal component analysis step reducing the data burden. Additionally, overall and disease-free survival analyses were performed with the optimal cutpoint determination by Evaluate Cutpoints software to establish the character of particular Notch components in tumorigenesis. In addition to the review, we demonstrated separate models of the examined cancers of the Notch pathway and its targets, although expression profiles of all normal tissues were much more similar to each other than to its cancerous compartments. Such Notch-driven cancerous differentiation resulted in a case of opposite association with DFS and OS. As a consequence, target genes also show very distinct profiles including genes associated with cell proliferation and differentiation, energy metabolism, or the EMT. In conclusion, the observed Notch associations with the female tract malignancies resulted from differential expression of target genes. This may influence a future analysis to search for new therapeutic targets based on specific Notch pathway profiles.
Real-Time Energy Management Strategy Based on Driver-Action-Impact MPC for Series Hybrid Electric Vehicles

Precise prediction of future vehicle information can improve the control efficiency of hybrid electric vehicles. Nowadays, most prediction models use previous information of vehicles to predict future driving velocity, which cannot reflect the impact of the driver and the environment. In this paper, a real-time energy management strategy (EMS) based on driver-action-impact MPC is proposed for series hybrid electric vehicles. The proposed EMS consists of two modules: the velocity prediction module and the real-time MPC module. In the velocity prediction module, a long short-term memory (LSTM) neural network model, which is trained by the traffic data derived from a VR-based driving simulator, is adopted to predict the future driving information by using driver action information and current vehicle’s velocity. The obtained future driving velocity is treated as the inputs of the real-time MPC module, which outputs the control variables to act on the underlying controllers of power components by solving a standard quadratic programming (QP) problem. Compared with the rule-based strategy, a 5.6% average reduction of fuel consumption is obtained. The effectiveness of real-time computation of the EMS is validated and verified through a hardware-in-the-loop test platform.
Saturation Number of Berge Stars in Random Hypergraphs

Let $G$ be a graph. We say an $r$-uniform hypergraph $H$ is a Berge-$G$ if there exists a bijection $\phi: E(G)\to E(H)$ such that $e\subseteq\phi(e)$ for each $e\in E(G)$. Given a family of $r$-uniform hypergraphs $\mathcal{F}$ and an $r$-uniform hypergraph $H$, a spanning sub-hypergraph $H'$ of $H$ is $\mathcal{F}$-saturated in $H$ if $H'$ is $\mathcal{F}$-free, but adding any edge in $E(H)\backslash E(H')$ to $H'$ creates a copy of some $F\in\mathcal{F}$. The saturation number of $\mathcal{F}$ is the minimum number of edges in an $\mathcal{F}$-saturated spanning sub-hypergraph of $H$. In this paper, we asymptotically determine the saturation number of Berge stars in random $r$-uniform hypergraphs.
Feature Guided CNN for Baby's Facial Expression Recognition

State-of-the-art facial expression methods outperform human beings, especially, thanks to the success of convolutional neural networks (CNNs). However, most of the existing works focus mainly on analyzing an adult’s face and ignore the important problems: how can we recognize facial expression from a baby’s face image and how difficult is it? In this paper, we first introduce a new face image database, named BabyExp, which contains 12,000 images from babies younger than two years old, and each image is with one of three facial expressions (i.e., happy, sad, and normal). To the best of our knowledge, the proposed dataset is the first baby face dataset for analyzing a baby’s face image, which is complementary to the existing adult face datasets and can shed some light on exploring baby face analysis. We also propose a feature guided CNN method with a new loss function, called distance loss, to optimize interclass distance. In order to facilitate further research, we provide the benchmark of expression recognition on the BabyExp dataset. Experimental results show that the proposed network achieves the recognition accuracy of 87.90% on BabyExp.
Studies of natural and synthetic agardites

Agardite of formula [(Al, Nd, REE)Cu(AsO) (OH)·3HO] has been discovered at Cobar, New South Wales, Australia. A series of synthetic agardites were analysed by X-ray diffraction and a correlation exists between the effective ionic radius of the REE in the M site and the unit cell size for each respective agardite mineral. No value for the effective ionic radius of 9-coordinate Bi has been reported but a value of approximately 115.5 pm is estimated from this correlation. The results of the TGA analyses show that the synthetic agardites are all fully hydrated, i.e., n = 3. Near infrared spectroscopy and mid- infrared spectroscopy has been used to characterise a group of synthetic agardites of formula ACu (AsO)(OH)· 3HO where A is a rare earth element. The hydroxyl stretching region is characterised by four bands observed at around 3568, 3489, 3382 and 3290 cm. The first two bands are attributed to the stretching mode of hydroxyl units and the last two bands to water stretching vibrations. The position of these bands indicates strongly hydrogen bonded water. The water in agardites is zeolitic type water. Near-IR spectroscopy shows a series of bands at 7242, 7007, 6809, 6770 and 6579 cm attributed to the first overtones of the hydroxyl fundamentals. The NIR spectrum of agardite (Sm) is different and may be affected by electronic bands. Combination bands are observed at around 4404, 4343, 4340, 4294 and 4263 cm. Bands attributed to water combination modes are found at around 5200, 5173, 5082 and 4837 cm. Agardites are a group of minerals known for their REE content and have been rarely studied. NIR spectroscopy is an excellent technique for the characterisation and ready identification of these minerals.
Integrated Deep Neural Networks-Based Complex System for Urban Water Management

Although the management and planning of water resources are extremely significant to human development, the complexity of implementation is unimaginable. To achieve this, the high-precision water consumption prediction is actually the key component of urban water optimization management system. Water consumption is usually affected by many factors, such as weather, economy, and water prices. If these impact factors are directly combined to predict water consumption, the weight of each perspective on the water consumption will be ignored, which will be greatly detrimental to the prediction accuracy. Therefore, this paper proposes a deep neural network-based complex system for urban water management. The essence of it is to formulate a water consumption prediction model with the aid of principal component analysis (PCA) and the integrated deep neural network, which is abbreviated as UWM-Id. The PCA classifies the factors affecting water consumption in the original data into three categories according to their correlation and inputs them into the neural network model. The results in the previous step are assigned weights and integrated into the form of fully connected layer. Finally, analyzing the sensitivity of the proposed UWM-Id and comparing its performance with a series of commonly used baseline methods for data mining, a large number of experiments have proved that UWM-Id has good performance and can be used for urban water management system.
Adaptive Attention with Consumer Sentinel for Movie Box Office Prediction

To improve the movie box office prediction accuracy, this paper proposes an adaptive attention with consumer sentinel (LSTM-AACS) for movie box office prediction. First, the influencing factors of the movie box office are analyzed. Tackling the problem of ignoring consumer groups in existing prediction models, we add consumer features and then quantitatively analyze and normalize the box office influence factors. Second, we establish an LSTM (Long Short-Term Memory) box office prediction model and inject the attention mechanism to construct an adaptive attention with consumer sentinel for movie box office prediction. Finally, 10,398 pieces of movie box office dataset are used in the Kaggle competition to compare the prediction results with the LSTM-AACS model, LSTM-Attention model, and LSTM model. The results show that the relative error of LSTM-AACS prediction is 6.58%, which is lower than other models used in the experiment.
Axial mixing in pipes

The problem of axial mixing in straight pipes is analyzed by a modification of G. I. Taylor's analysis. The treatment presented here includes the effect of both Schmidt and Reynolds numbers throughout the turbulent-flow range. All applicable data on flow of gases and liquids are found to confirm the validity of the method. The analysis indicates that axial mixing increases rapidly as the flow approaches the laminar region, especially for liquids, and that pipe roughness causes a relatively small increase in axial mixing. Turbulent eddy diffusion in the axial direction has a negligible effect. The results of the analysis are applicable to those systems wherein the kinematic viscosity of the flowing mixture does not vary greatly from one region to another and in which the concentration region of interest is spread out along a sufficient length of pipe. These limitations are broad enough to permit most practical problems to be treated by the method.
PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON MOLECULAR SIMULATION Diffusion of cations in salt solutions between ice walls

It is important for food, medical and energy engineering to control ice growth during cooling processes. Adding salts and antifreeze protein to water is a promising method for doing this. However, the effects of ions in solution on ice–water interface in narrow spaces have not yet been clarified. Therefore, we carried out molecular dynamics simulations of sodium chloride, potassium chloride and calcium chloride in water between ice walls. It was found that the peaks of the radial distribution function for calcium ions are highest among the cations. In addition, the diffusion coefficient of calcium ions was lower than those of the other ions. A further finding was that one water molecule on the interface and two water molecules adjacent to the interface in liquid phase were positioned in the first or second hydration shell for the calcium ion, which was located at the closest point to the interface. Such hydration shells caused the reductions in motion and diffusion coefficient of the specific calcium ion.
Hierarchical Composite Electrodes of Nickel Oxide Nanoflake 3D Graphene for High‐Performance Pseudocapacitors

NiO nanoflakes are created with a simple hydrothermal method on 3D (three‐dimensional) graphene scaffolds grown on Ni foams by microwave plasma enhanced chemical vapor deposition (MPCVD). Such as‐grown NiO‐3D graphene hierarchical composites are then applied as monolithic electrodes for a pseudo‐supercapacitor application without needing binders or metal‐based current collectors. Electrochemical measurements impart that the hierarchical NiO‐3D graphene composite delivers a high specific capacitance of ≈1829 F g−1 at a current density of 3 A g−1 (the theoretical capacitance of NiO is 2584 F g−1). Furthermore, a full‐cell is realized with an energy density of 138 Wh kg−1 at a power density of 5.25 kW kg−1, which is much superior to commercial ones as well as reported devices in asymmetric capacitors of NiO. More attractively, this asymmetric supercapacitor exhibits capacitance retention of 85% after 5000 cycles relative to the initial value of the 1st cycle.
Diffraction by crystals with planar faults. III. Structure analyses using microtwins

The general theory for kinematical diffraction from crystals having planar faults is applied to the case of microtwinning and the related cases occurring in some minerals where there is a disordered sequence of two types of structure having small differences in composition, unit-cell dimensions and axial orientations. It is shown that, if intensities are measured for unresolved or partially resolved pairs of diffraction spots using conventional techniques, errors may well arise if the measurements are interpreted on the usual assumption that the intensities from the different crystal regions are summed incoherently. Calculations for representative cases suggest that errors, due to the neglect of the spreading of intensity maxima into continuous streaks, may amount to 20 or 30% when overlapping diffraction spots have structure amplitudes of opposite sign, but are usually much smaller, especially if the structure amplitudes are of the same sign.
Low temperature poly-Si thin-film transistor fabrication by metal-induced lateral crystallization

A new low temperature crystallization method for poly-Si TFTs was developed: Metal-Induced Lateral Crystallization (MILC). The a-Si film in the channel area of a TFT was laterally crystallized from the source/drain area, on which an ultrathin nickel layer was deposited before annealing. The a-channel poly-Si TFTs fabricated at 500/spl deg/C by MILC showed a mobility of 121 cm/sup 2//V/spl middot/s, a threshold voltage of 1.2 V, and an on/off current ratio of higher than 10/sup 6/. These electrical properties are much better than TFTs fabricated by conventional crystallization at 600/spl deg/C.
Thermodynamics of Mixing for Statistical Copolymers of Ethylene and α-Olefins

The melt-state interactions that govern phase behavior in polyolefin blends were evaluated by small-angle neutron scattering (SANS) and compared with earlier results for structurally similar model polymers. The materials are statistical copolymers of ethylene with a range of propylene, 1-butene, 1-hexene, and 1-octene contents, made by metallocene catalysis. They are modestly polydisperse (Mw/Mn ∼ 2) and not available in deuterated form, thus requiring modification of the procedures used for the nearly monodisperse and easily deuterated model polymers. The SANS intensity expression for polydisperse components was confirmed independently, and two experimental procedures, employing binary and ternary blends with deuterated model components, were used. The interactions obey a solubility-parameter formalism, in agreement with the earlier studies. Moreover, the values of δ − δref obtained for the α-olefin copolymers were found to depend only on w, the weight fraction of α-olefin comonomer. Finally, this δ − δr.
EXPLORING THE NEXUS BETWEEN INNOVATION AND EMPLOYEE PERFORMANCE – EMPIRICAL EVIDENCE FROM NIGERIAN MANUFACTURING INDUSTRY

Innovation reflects the tendency of a firm to enhance, appreciate and acquire new ideas, novelty, experimentation and the creative processes that may result in new products, services or technological process. The choice of appropriate innovation mix required to enhance organizational performance therefore becomes germane. This study examined the impact of innovation mix in developing countries. Survey research design was used in the study. Data for this research was obtained from Primary sources through the aid of a structured questionnaire. Krejche and Morgan formular were used to estimate the sample size. 368 copies of questionnaires were administered, out of which 309 were found to be useful for the analysis representing valid response rate. The data were analyzed using descriptive statistics and inferential statistics of partial least square structural equation model (PLS-SEM). The hypothesis was tested at 0.05 alpha levels. Findings revealed that there is a significant relationship between innovation mix and market performance (R = .643, & P< .000). Three components of innovation mix, product (β = .310, t= 4.269, p< .000) process (β = .178, t= 3.047, p< .002) market (β =.317, t= 4.720, p<.000) were found to be significantly related to market performance while the fourth component, organization (β = .080, t= 1.390, p< .165) was not significant. The findings of the study revealed that indeed the adoption and implementation of innovative practices makes an organization not only to be proactive to changes but also initiate positive changes that consequently leads to competitive advantage, improved market performance and sustainable performance. It was recommended that organizations should continuously maintain, sustain and improve innovative practices since it is an indispensable tool for improved market performance. Based on the findings of this study, the study concluded that innovative performance is the main vehicle to convey the positive effects of innovation types to market performance. It was recommended that organizations should continuously engage in market innovation practices in order to generate extra value for their customers whilst thriving to cut costs, increase productivity and sustain competitive edge in today’s market.
Return Horizon and Mutual Fund Performance

Investment performance depends on return measurement horizon. The percentage of U.S. equity mutual funds that outperform the SPY is 46.9% in monthly returns, 39.9% in annual returns, and 29.5% in full-sample (1991-2008) returns. Further, true alphas vary with return measurement horizon, and the effect of horizon on alpha is asymmetric in beta. We introduce and implement methods to estimate long-horizon alphas and betas. Compared to a benchmark of 40.9% in monthly returns, the percentage of funds with positive alpha estimates decreases to 16.7% (increases to 49.1%) at long return measurement horizons for funds with high (low) estimated monthly market betas.
Fertigungssystemszenarien

Kurzfassung Der technologische Fortschritt führt dazu, dass eingesetzte Technologien in der Fertigung schneller veralten und mit diesen nicht mehr wirtschaftlich gefertigt werden kann. Dieser Umstand verursacht unter anderem die Notwendigkeit von Technologiesubstitutionen. Damit Unternehmen nicht in die Situation geraten, von besonders innovativen technologischen Neuerungen überrascht zu werden, ist eine systematische Technologievorausschau notwendig. Die Entwicklung von Fertigungssystemszenarien ermöglicht es, mögliche zukünftige Technologiekombinationen und damit auch die Technologiesubstitution in der Fertigung vorauszudenken.
Bifunctionalized Allenes. Part XXIII. An Efficient Method for Regioselective Synthesis of 5-Phosphorylated Allenecarboxylates

Abstract An efficient method for regioselective synthesis of 5-(dimethoxyphosphoryl)-allenecarboxylates by an atom economical [2,3]-sigmatropic rearrangement of the mediated 3-(dimethoxyphosphanyloxy)-alk-4-ynoates is described. Alkyl 5-(dimethoxyphosphoryl)-alka-3,4-dienoates can be readily prepared via reaction of alkyl 3-hydroxy-alk-4-ynoates with dimethylchlorophosphite in the presence of a base. Alkyl 3-hydroxy-alk-4-ynoates were prepared by reaction of the metallated acetylenes with commercialy available alkyl 3-oxoalkanoates.
An Empirical Investigation of the Mediating Role of Customer Attachment in South African Private Hospitals

Abstract Background and purpose: Relationship marketing literature acknowledges the important role of attachment in customer-organization relationships, but shows limited theoretical and empirical understanding of the factors that contribute to the development and maintenance of attached customers. To address this gap, this paper draws on the relationship marketing view and synthesizes important relationship constructs with the aim of developing a mediated attachment model for private hospitals in South Africa. Design/Methodology/Approach: A quantitative descriptive research design was implemented, collecting 303 useable questionnaires via non-probability convenience sampling. Cronbach’s alpha coefficients and a confirmatory factor analysis were conducted to determine the reliability and validity of the measures respectively, and a SEM was conducted for the mediation analysis. Results: The results indicate that respondents’ relationship value was significantly related to attachment, loyalty and fear of relationship loss, and attachment was significantly related to loyalty and fear of relationship loss. Moreover, the indirect effect of attachment in the relationship between relationship value and loyalty, as well as in the relationship between relationship value and fear of relationship loss was found to be significant. Conclusion: Attachment plays a significant role in both the direct and indirect relationships with key relationship marketing constructs. The importance of attachment in building patient-hospital relationships should therefore not be ignored, and private hospitals are encouraged to invest in their relationships with patients, with the aim of establishing attachment.
Surface energies of solid metals

AbstractMeasurements of surface energies of solid metals reported in the literature are collected and compared, and best values are suggested. A brief review is presented of theories of surface free energy γ and surface entropy S, and it is proposed that S ∼ 1.0 R per mole of surface atoms is a reasonable estimate. Using this value of S, surface energies γo at 0°K are deduced by extrapolation of experimental data from higher temperatures and correlated with cohesive energies H(O) at 0°K. On the basis of this correlation, it is suggested that reasonable estimates of surface energy reliable to ∼ 10 per cent may be obtained fromγA=γoA−TSwhere A = molar surface area, γoA = 0.25 H(O), and S ;amp;#x003D; 1.0 R. Resume. On a rassemble dans la litterature les mesures d'energie superficielle de metaux solides. De leur comparaison l'auteur suggere les meilleures valeurs disponibles. On presente aussi une breve revue des theories concernant l' energie libre de surface Set l'entropie superficielle γ. La valeur de 1.0.
Valuation and Performance Consequences of Cross-border Acquisitions: Indian Acquirers and Foreign Targets

This paper studies the role of the merger motives driving a cross-border merger/ acquisition in an emerging economy context and its impact upon the short term value creation for the acquiring firm. We classify the deals using broad explorationexploitation constructs using content analysis and through an event study determine that Indian cross-border acquirers create value through cross-border M&A in the short run. The exploration motive is found to be associated with significantly higher acquirer gains compared to deals motivated by exploitation.