Miracle-dz/UniFAR-FTUs huggingface dataset:
Current and Conventional Appraisal Trends in Hotels

The Indian tourism and cheerfulness industry has created as one of the key drivers of improvement among the organizations division in India. Tourism in India has basic potential considering the rich social and recorded legacy, grouping in environment, scenes and spots of consistent greatness spread the country over. Tourism is in like manner a perhaps considerable work generator other than being basic wellspring of remote exchange for the country. The Indian economy is opening up its perspectives as it continues organizing with the world economy. Thusly, the advantages of driving business with and in India are various. This has lead to the moving of variety of occupations to the shores of India, securing its wake travel pioneers, business voyagers, business meets, and event seekers. The major focus of the study is to perceive the Performance Appraisal methodologies and procedures used as a piece of Indian Hotels. In order to appreciate the present and routine assessment designs in Hotels, to appreciate the utilization of Appraisal frameworks in Hotel Industry, to know how to improve the Potential of employees, to find the requirement or necessity of dev. & training for employees at different level, to improve the communication among the employees, feedback system of employees working in the organization, to know the levels of the awareness and satisfaction in employees, to identify the effectiveness of Potential Appraisal. The scope of study was enlistment and Selection is incredibly effective gadget to improve the Standard of specialist Team in a Hotel. It optimizes the use of human capital for growth & development of Hotel.
A prospective study of the diagnostic value of urinary thromboxane in patients presenting with acute chest pain

Abstract. In chance single‐case observations thromboxane excretion has been reported to increase several days prior to myocardial infarction. To test its frequency and potential diagnostic value we prospectively measured thromboxane excretion in 166 consecutive patients who had presented to the emergency unit with acute chest pain indicative of ischaemia. Thromboxane excretion at presentation was increased, sometimes dramatically, in 17 of 33 (52%) patients with unstable angina, in 42 of 73 (57%) patients with definite myocardial infarction, but in only two of 14 (14%) patients with stable angina. Nineteen of 29 patients undergoing early angiography had detectable intracoronary thrombi, and these patients excreted significantly more thromboxane than patients without thrombi. Ongoing platelet activation may be detected by increased thromboxane excretion in more than 50% of the patients presenting with unstable angina and myocardial infarction, particularly in those with intracoronary thrombi, but it is not a general phenomenon that can be used in diagnosis.
Burkholderia cepacia complex bacteria: opportunistic pathogens with important natural biology

Interaction with plants around their roots and foliage forms the natural habitat for a wide range of gram‐negative bacteria such as Burkholderia, Pseudomonas and Ralstonia. During these interactions many of these bacteria facilitate highly beneficial processes such as the breakdown of pollutants or enhancement of crop growth. All these bacterial species are also capable of causing opportunistic infections in vulnerable individuals, especially people with cystic fibrosis (CF). Here we will review the current understanding of the Burkholderia cepacia complex (Bcc) as a group of model opportunistic pathogens, contrasting their clinical epidemiology with their ecological importance. Currently, the B. cepacia complex is composed of nine formally named species groups which are all difficult to identify using phenotypic methods. Genetic methods such as 16S rRNA and recA gene sequence analysis have proven useful for Bcc species identification. Multilocus sequence typing (MLST) is also emerging as a very useful tool for both Bcc strain and species identification. Historically, Burkholderia cenocepacia was the most dominant Bcc pathogen in CF, however, probably as a result of strict infection control practices introduced to control the spread of this species, its prevalence has been reduced. Burkholderia multivorans is the now the most dominant Bcc infection encountered in the UK CF population, a changing epidemiology that also appears to be occurring in the US CF population. The distribution of Bcc species residing in the natural environment may vary considerably with the type of environment examined. Clonally identical Bcc strains have been found to occur in the natural environment and cause infection. The contamination of medical devices, disinfectants and pharmaceutical formulations has also been directly linked to several outbreaks of infection. In the last 10 years considerable progress has been made in understanding the natural biology and clinical infections caused by this fascinating group of bacteria.
Mineral metabolism in renal transplant recipients discontinuing cinacalcet at the time of transplantation: a prospective observational study

Evenepoel P, Sprangers B, Lerut E, Bammens B, Claes K, Kuypers D, Meijers B, Vanrenterghem Y. Mineral metabolism in renal transplant recipients discontinuing cinacalcet at the time of transplantation: a prospective observational study. Clin Transplant 2011 DOI: 10.1111/j.1399‐0012.2011. 01524.x. © 2011 John Wiley & Sons A/S.
An evolutionary process that assembles phenotypes through space rather than through time

In classical evolutionary theory, traits evolve because they facilitate organismal survival and/or reproduction. We discuss a different type of evolutionary mechanism that relies upon differential dispersal. Traits that enhance rates of dispersal inevitably accumulate at expanding range edges, and assortative mating between fast-dispersing individuals at the invasion front results in an evolutionary increase in dispersal rates in successive generations. This cumulative process (which we dub “spatial sorting”) generates novel phenotypes that are adept at rapid dispersal, irrespective of how the underlying genes affect an organism's survival or its reproductive success. Although the concept is not original with us, its revolutionary implications for evolutionary theory have been overlooked. A range of biological phenomena (e.g., acceleration of invasion fronts, insular flightlessness, preadaptation) may have evolved via spatial sorting as well as (or rather than) by natural selection, and this evolutionary mechanism warrants further study.
Infrastructure, Education, and Economic Development in India: A State Level Analysis

A large number of studies reveal that regions with larger stocks of physical infrastructure and human capital often are associated higher level of economic development. The present chapter attempts to find whether this is valid for India. Factor Analysis has been used to find the index of scores of infrastructure of the selected 20 major states of India. We have then used regression analysis to find the impact of infrastructure and education on economic development of the states. The results indicate that there is huge variation of infrastructure development across the states in India. The findings also indicate the significant impact of infrastructure development and education on economic development of the state, measured in terms of Per Capita Net State Domestic Product (PCNSDP).
Associations of ATF4 gene polymorphisms with schizophrenia in male patients

Activating transcription factor 4 (ATF4) is considered as a positional candidate gene for schizophrenia due to its location at chromosome 22q13, a region linked to schizophrenia. Furthermore, as protein interaction partner of ATF4, disrupted in schizophrenia 1 (DISC1) and its signal pathway implicated in the pathophysiology of schizophrenia have been widely supported by a number of genetic and neurobiological studies. Our aim was to investigate whether ATF4 is associated with schizophrenia in case–control samples of Han Chinese subjects consisting of 352 schizophrenia patients and 357 healthy controls. We detected 18 single nucleotide polymorphisms (SNPs) in ATF4 locus, two of which were analyzed, including one insertion at the putative core promoter region (rs17001266, –/C) and one nonsynonymous variant in exon 1 (rs4894, C/A, Pro22Gln). Allele distributions of two SNPs showed significant associations with schizophrenia in male subjects (respectively, rs17001266: P = 0.021, OR = 1.58, 95% CI = 1.07–2.33; rs4894: P = 0.004, OR = 1.78, 95% CI = 1.19–2.67), but not in female subjects as well as the entire population. Two haplotypes CC and ‐A constructed of rs17001266–rs4894 also revealed significant associations with schizophrenia in male group (global P = 0.0097). These findings support that ATF4 gene may be involved in susceptibility to schizophrenia with sex‐dependent effect in the Chinese Han population and suggest that further functional assays are needed to verify their relevance to the pathogenesis of schizophrenia. © 2007 Wiley‐Liss, Inc.
Recommendations for Analyzing and Reporting TP53 Gene Variants in the High‐Throughput Sequencing Era

The architecture of TP53, the most frequently mutated gene in human cancer, is more complex than previously thought. Using TP53 variants as clinical biomarkers to predict response to treatment or patient outcome requires an unequivocal and standardized procedure toward a definitive strategy for the clinical evaluation of variants to provide maximum diagnostic sensitivity and specificity. An intronic promoter and two novel exons have been identified resulting in the expression of multiple transcripts and protein isoforms. These regions are additional targets for mutation events impairing the tumor suppressive activity of TP53. Reassessment of variants located in these regions is needed to refine their prognostic value in many malignancies. We recommend using the stable Locus Reference Genomic reference sequence for detailed and unequivocal reports and annotations of germ line and somatic alterations on all TP53 transcripts and protein isoforms according to the recommendations of the Human Genome Variation Society. This novel and comprehensive description framework will generate standardized data that are easy to understand, analyze, and exchange across various cancer variant databases. Based on the statistical analysis of more than 45,000 variants in the latest version of the UMD TP53 database, we also provide a classification of their functional effects (“pathogenicity”).
Fuzzy Clustering using Credibilistic Critical Values

In this paper, the utility of credibilistic critical values in crisp conversion of fuzzy data sets is considered. Conversion of this type becomes essential mainly when clustering of fuzzy data sets is carried out. In this paper performance of two popular clustering algorithms namely Fuzzy c–means and Fuzzy c–medoids algorithms are evaluated under credibilistic critical value crisp conversion is carried out. Two synthetic data sets of varying nature are used in the comparative study. Some popular fuzzy clustering validity measures were employed in this study. KeywordsClustering, Critical values, Credibility space, Partition Coefficient, Partition Entropy, FS Index, XB Index
Evaluation of an Anti-Inflammatory Factor Derived from Hyperimmunized Cows 1

Abstract An anti-inflammatory factor isolated from milk of hyperimmunized cows was analyzed in vitro and in vivo. Macrophages collected from lacteal secretions of a unimmunized nonlactating cow showed increased ability to kill phagocytosed Staphylococcus aureus when incubated with the anti-inflammatory factor. Mice injected intraperitoneally with 10 mg/kg of anti-inflammatory factor demonstrated an increased LD50 to S. aureus when challenged intraperitoneally. Injected mice also demonstrated significantly (P < 0.05) less mammary inflammation and involution and increased clearance of S. aureus when challenged intramammarily. Quantitative histologic analysis of mammary tissues from mice injected with antiinflammatory factor demonstrated significantly (P < 0.05) more lumen, less interalveolar connective tissue, and less leukocytic infiltration compared with control mice. Mammary glands of mice injected with anti-inflammatory factor and challenged with S. aureus also contained fewer colony-forming units than control mice. The product appeared to exert its effect on the nonspecific defense system via modulation of leukocyte function.
An investigation on motion periodic series for fire and smoke textures characteristic identification

Dynamic texture describes the images sequence that continuously demonstrates movement of pixel's intensity change patterns in time. Two motion features, namely average radius and motion coherence index are extracted to find the different characteristics of fire and smoke. Since, the average radius of motion vectors describes the rapid of intensity change, whilst the motion coherence index has been developed to assess the coherent motion of intensity change. We propose a cutting-edge periodic series analysis to characterize fire and smoke dynamic textures. Our experimental results demonstrate the periodic motion pattern of fire and smoke. Besides, the periodicity index calculated by our proposed method is efficiently able to characterize fire and smoke dynamic textures, higher efficiency than calculated by traditional approach.
A Case Study on Suitable Area and Resource for Development of Floating Photovoltaic System

— In development of floating photovoltaic generation system, finding a suitable place of installation is as important as development of economically feasible and stable structure. Especially since floating photovoltaic system has its facility floating on water surface, it is extremely important to review the effects of weather conditions such as wind, water flow and floating matters, various factors (such as fogs) that can reduce generation efficiency, possibility of connection with power system, and legal restrictions. The method of investigating suitable area and resource for development of tracking-type floating photovoltaic generation system was proposed in this paper, which can be used for development of floating and ocean photovoltaic system in the future.
Occupations, age and gender: Men and women’s earnings in the Irish labour market

While many studies investigate gender wage disparities, few have examined the impact of gender, education, part-time working and sector on earnings for men and women across different occupational groups and for different age groups. The purpose of this article is to undertake a more nuanced approach to further our understanding of the gender pay difference between men and women in different occupations in order to tackle and close this gap. The study’s findings suggest that the labour market is segmented into primary and secondary jobs. Additionally, the earnings returns for education are generally lower for women compared to men and women appear to fare better in the public sector in terms of a lower earnings gap for full-time and part-time employees and higher returns for education compared to women working in the private sector. The article concludes with a discussion of the policy implications.
Real‐time cellular uptake of serotonin using fluorescence lifetime imaging with two‐photon excitation

The real‐time uptake of serotonin, a neurotransmitter, by rat leukemia mast cell line RBL‐2H3 and 5‐hydroxytryptophan by Chinese hamster V79 cells has been studied by fluorescence lifetime imaging microscopy (FLIM), monitoring ultraviolet (340 nm) fluorescence induced by two‐photon subpicosecond 630 nm excitation. Comparison with two‐photon excitation with 590 nm photons or by three‐photon excitation at 740 nm shows that the use of 630 nm excitation provides optimal signal intensity and lowered background from auto‐fluorescence of other cellular components. In intact cells, we observe using FLIM three distinct fluorescence lifetimes of serotonin and 5‐hydroxytryptophan according to location. The normal fluorescence lifetimes of both serotonin (3.8 ns) and 5‐hydroxytryptophan (3.5 ns) in solution are reduced to ∼2.5 ns immediately on uptake into the cell cytosol. The lifetime of internalized serotonin in RBL‐2H3 cells is further reduced to ∼2.0 ns when stored within secretory vesicles. Microsc. Res. Tech., 2008. © 2007 Wiley‐Liss, Inc.
“Engage and attract me, then I’ll share you”: an analysis of the impact of post category on viral marketing in a social networking site

Purpose – The purpose of this paper is to analyze the impact of different types of content of viral marketing in a popular social networking site. Our research is founded on recent studies which categorize posts on Facebook. Design/methodology/approach – Data for 2583 posts in eight profiles of Brazilian beer brands were coded and analyzed. We used a regression model and Analysis of Variance to establish relationships among independent variables and a dependent variable. Findings – Two hypotheses were supported. There was a positive relationship between posts of the categories Fan and Promotion and Publicity and viral marketing. Posts of the categories Information and Pool did not have any significant effects, and confirmed previous studies which analyzed likes and comments as dependent variables. Originality/value – Previous studies using the platform did not categorize posts created by brand fans/followers. Our typology is a quantitative improvement in relation to studies with similar objectives. Hence, marketers involved with brand management on Facebook should publish posts which promote the brand and reproduce content generated by people engaged with it if they seek to increase the viralization capacity of such posts.
Parametric nonlinear lumped element model for circular CMUTs in collapsed mode

We present a parametric equivalent circuit model for a circular CMUT in collapsed mode. First, we calculate the collapsed membrane deflection, utilizing the exact electrical force distribution in the analytical formulation of membrane deflection. Then we develop a lumped element model of collapsed membrane operation. The radiation impedance for collapsed mode is also included in the model. The model is merged with the uncollapsed mode model to obtain a simulation tool that handles all CMUT behavior, in transmit or receive. Large- and small-signal operation of a single CMUT can be fully simulated for any excitation regime. The results are in good agreement with FEM simulations.
Decision making for health care professionals: use of decision trees within the community mental health setting.

AIM OF THE PAPER To examine the application of the decision tree approach to collaborative clinical decision-making in mental health care in the United Kingdom (UK). BACKGROUND While this approach to decision-making has been examined in the acute care setting, there is little published evidence of its use in clinical decision-making within the mental health setting. The complexities of dual diagnosis (schizophrenia and substance misuse in this case example) and the varied viewpoints of different professionals often hamper the decision-making process. This paper highlights how the approach was used successfully as a multiprofessional collaborative approach to decision-making in the context of British community mental health care. DESIGN A selective review of the relevant literature and a case study application of the decision tree framework. CONCLUSIONS The process of applying the decision tree framework to clinical decision-making in mental health practice can be time consuming and client inclusion within the process is not always appropriate. The approach offers a method of assigning numerical values to support complex multiprofessional decision-making as well as considering underpinning literature to inform the final decision. Use of the decision tree offers a common framework that can assist professionals to examine the options available to them in depth, while considering the complex variables that influence decision-making in collaborative mental health practice. Use of the decision tree warrants further consideration in mental health care in terms of practice and education.
Policy networks across portfolio boundaries: An analysis of integrated public health policy in Dutch municipalities

Regardless efforts by the (municipal) public health sector, public health still faces major problems. The involvement of other policy sectors is generally assumed as necessary. Because, in contrast to the public health sector, they have policy instruments to address the environmental determinants of health. The idea is that intersectoral policy networks will be established and integrated public health policy (IPHP) will be developed. IPHP is assessed as promising, due to the integration of health considerations into policies of non-public health sectors, i.e., in policy networks across portfolio boundaries. However, there is a lack of empirical evidence on the conditions under which these assumptions about IPHP are true. This study provides insights in the empirical manifestations of IPHP and the conditions under which IPHP leads to an integrated policy output in terms of addressing environmental determinants of health with multiple intervention strategies, policy innovation and perceived public health gain. We concluded that network intersectorality mattered to a certain extent and under specific conditions and that other conditions were also important. Such as the execution of network management strategies, horizontal network integration, a broad policy approach, the involvement of implementing actors in the policy development phase, a project leader from a non-public health sector. There is not one road leading to Rome, but various possibilities and combinations of conditions lead to an integrated policy output. When keeping such nuances in mind, possibilities arise for the realization of policy networks across portfolio boundaries in which an integrated policy output can be realized with IPHP.
Role of the Media in Vascular Injury: Atherosclerosis and Dissection

Although a metabolic role for endothelium in toxic injury has been well established, a similar role has not been as thoroughly explored for the vascular media. In this study two forms of vascular medial involvement in toxic injury are examined. Early atherosclerotic plaques are studied by immunohistochemistry for an α class glutathione-S-transferase (GST) isozyme known as hGSTA4-4, which has preferential metabolic activity for α, β-unsaturated aldehydes derived from lipid peroxidation, especially 4-hydroxy-2-nonenal. Findings in human plaque indicate that hGST A4-4 is highly upregulated in vascular smooth muscle cells (VSMCs) within the plaque and in the medial VSMCs underlying plaque. Endothelial cells, while not expressing hGST A4-4 distant from plaques, were found to express the isozyme in cytoplasm overlying plaque. In a series of second experiments, we illustrate a developmental model of dissecting aortic aneurysm (DAA) obtained by administering semicarbazide, an inhibitor of the little-studied VSMC enzyme semicarbazide-sensitive amine oxidase (SSAO), to pregnant rats during the last trimester of development. Newborn rats consistently developed DAA which is characterized by splitting of media of ascending thoracic aorta and extensive blood collections surrounding the vessel. These experimental examples emphasize the potential role of the media in toxic insults to blood vessels. Also, the potential importance of toxic injury to developing blood vessels by in utero exposure to xenobiotic substances is illustrated.