Miracle-dz/UniFAR-FTUs huggingface dataset:
Understanding the Role of Business Analytics Applications in Healthcare Value Chain

This research explores how healthcare organizations are leveraging business analytics (BA) capabilities and techniques to create value and improve care quality. Given the increasing interest and investment in BA, it is important to have a good understanding of what analytics capabilities healthcare organizations are utilizing to enhance value. Using Burns et al. (2002) healthcare value chain framework as a basis, we will identify the various analytics techniques/capabilities and subsequently classify them into three generally accepted classification of analytics: descriptive, predictive and prescriptive. Based on extensive search of the literature, complimented by a follow-up case study of a large regional hospital, analytics applications will be mapped onto the healthcare value chain framework. The study will contribute to practice and academia by clearly illustrating how healthcare organizations currently utilizes or should be using analytic capabilities and techniques in order to enable them close the quality gaps.
Examining Applicability of RSQS with Added Dimensions for Organized Apparel Retailers in India

This study endeavours to validate and develop a scale for organized apparel retail stores, as there is a need to develop and validate a modified instrument. Primary data have been collected from selected organized apparel retailers. Statistical tools, exploratory factor analysis (EFA) and structural equation modeling (SEM), were applied. It revealed that Retail Service Quality Scale (RSQS) model in original form is deficient and less appropriate in the Indian context, modified scale (i.e., Apparel Store Service & Product Quality Scale [ASSPQS]) may exhibit strong model fit for apparel retail sector. The findings and recommendations will enable retail stores to gather insights into current levels of service and product quality and may facilitate them in the improvement of certain aspects in service and product quality of the stores.
PUPDroid - Personalized user privacy mechanism for android

The technological progress of mobile devices, the low cost of this device and the facility of use are increasing the usability of mobile devices. Since these devices provide access to network, its owner has access to almost limitless amount of data and can store more information than in his personal computer (like phone call record, list of contact and calendar). A point of attention is that these devices have some resources that, if misused, can be dangerous to the owner. The major number of existing mobile devices Operational System does not allow the owner to manage how the installed application installed is using hardware device and personal information. In this paper we will present a mechanism to transfer the control of access permission to the owner's device with personalized roles. The idea behind the mechanism is to provide to the device owner a way to control the access permission by installed applications providing flexibility to personalize the application privacy. Since the platform does not allow the user to change the application permission after it is installed, Android was chosen to develop the proof of concept of the mechanism because it is an open source mobile operational system. The results show that the mechanism will allow Android user to improve his device privacy and control how it is used since the roles of access for each application can be personalized. The mechanism will also provide a way for enterprises to build an application to manage the employee's device privacy.
Topology of a Human Equilibrative, Nitrobenzylthioinosine (NBMPR)-sensitive Nucleoside Transporter (hENT1) Implicated in the Cellular Uptake of Adenosine and Anti-cancer Drugs*

The human equilibrative nucleoside transporter hENT1, the first identified member of the ENT family of integral membrane proteins, is the primary mechanism for the cellular uptake of physiologic nucleosides, including adenosine, and many anti-cancer nucleoside drugs. We have produced recombinant hENT1 inXenopus oocytes and used native and engineeredN-glycosylation sites in combination with immunological approaches to experimentally define the membrane architecture of this prototypic nucleoside transporter. hENT1 (456 amino acid residues) is shown to contain 11 transmembrane helical segments with an amino terminus that is intracellular and a carboxyl terminus that is extracellular. Transmembrane helices are linked by short hydrophilic regions, except for a large glycosylated extracellular loop between transmembrane helices 1 and 2 and a large central cytoplasmic loop between transmembrane helices 6 and 7. Sequence analyses suggest that this membrane topology is common to all mammalian, insect, nematode, protozoan, yeast, and plant members of the ENT protein family.
Attention-Like Processes in Drosophila Require Short-Term Memory Genes

Although there is much behavioral evidence for complex brain functions in insects, it is not known whether insects have selective attention. In humans, selective attention is a dynamic process restricting perception to a succession of salient stimuli, while less relevant competing stimuli are suppressed. Local field potential recordings in the brains of flies responding to visual novelty revealed attention-like processes with stereotypical temporal properties. These processes were modulated by genes involved in short-term memory formation, namely dunce and rutabaga. Attention defects in these mutants were associated with distinct optomotor effects in behavioral assays.
Pleasure Experience and Emotion Expression in Patients with Schizophrenia

Background Impairments in emotional experience and expression have been observed in patients with schizophrenia. However, most previous studies have been limited to either emotional experience (especially anhedonia) or expression. Few studies have examined both the experience and expression of emotion in schizophrenia patients at the same time. Aims The present study aimed to examine pleasure experience and emotion expression in patients with schizophrenia. In particular, we specifically examined the relationship between emotion impairments (both pleasure experience and expression) and negative symptoms. Methods One hundred and fifty patients completed the Temporal Experience of Pleasure Scale and Emotional Expressivity Scale. Results Schizophrenia patients exhibited deficits in experiencing pleasure, but showed intact reported emotion expression. Patients with prominent negative symptoms showed reduced anticipatory pleasure, especially in abstract anticipatory pleasure. Conclusion The present findings suggest that patients with schizophrenia have deficits in pleasure experience, while their abilities to express emotion appear intact. Such deficits are more severe in patients with prominent negative symptoms.
Smoking Prevalence among Korean Female Cosmetics Sales Workers

Background: The rate of cigarette smoking among female is relatively low in East Asian countries. This study was performed to determine the rate of cigarette smoking among cosmetics sales workers and to analyze the factors related to this behavior. Methods: A self-reported questionnaire was administered to approximately 3,300 cosmetic sales workers employed by major department stores in South Korea. Of the 667 questionnaires returned, 507 were analyzed after excluding missing or inaccurate data. The rate of cigarette smoking and associated factors were analyzed via the chi-square test, t-test and multiple logistic regression analysis. Results: The prevalence of cigarette smoking among female cosmetics sales workers was 40.6%. Workers were more likely to smoke cigarettes if they had a lower level of education than a higher level of education (odds ratio (OR), 1.91, 95% confidence interval (CI), 1.31-2.78), according to the results of a multivariable adjusted logistic regression analysis that accounted for age, marital status, mental health, alcohol use, care giving status and self-rated health. The ORs of smoking for unmarried workers, workers who were not caregivers, workers with poor self-rated health and poor mental health were ＞ 1, but this finding was not significant. Compared to the general population, a greater proportion of people in the study population were “ever smoker” (22.9% vs. 55.4%). Conclusion: The rate of cigarette smoking was much greater among female cosmetics sales workers in Korea than among the general population. Targeted tobacco control policy is urgently needed for this subgroup.
Protective role of uncoupling protein‐2 against dextran sodium sulfate‐induced colitis

Background and Aims: Uncoupling protein‐2 (UCP‐2) is a negative regulator of reactive oxygen species (ROS) production. We investigated the effect of UCP‐2 on disease progression in a murine dextran sodium sulfate (DSS)‐induced colitis model, and the expression and distribution of tight junction (TJ) proteins, such as occludin, zonula‐1 (ZO‐1), claudin‐4, and junctional adhesion molecule‐1 (JAM‐1).
Physiological function and molecular basis of STIM1‐mediated calcium entry in immune cells

Summary: Calcium signals in immune cells regulate a variety of physiological responses such as cell activation, differentiation, gene transcription, and effector functions. Surface receptor stimulation induces an increase in the concentration of cytosolic calcium ions (Ca2+), which are derived mainly from two sources, intracellular endoplasmic reticulum (ER) Ca2+ stores and the extracellular space. The major cascade for Ca2+ entry in immune cells is through store‐operated Ca2+ entry (SOCE) and Ca2+ release‐activated Ca2+ (CRAC) channels. Activation of SOCE is triggered by depletion of intracellular ER Ca2+ stores, but the molecular mechanism was a long‐standing issue. With the recent molecular identification of the ER Ca2+ sensor [stromal interacting molecule‐1 (STIM1)] and a pore‐forming subunit of the CRAC channel (Orai1), our understanding of the SOCE activation pathway has increased dramatically. These advances have now made it possible to shed some light on important questions: what is the physiological significance of SOCE, and what is its molecular basis? This review focuses on the recent progress in the field and the exciting opportunities for understanding how SOCE influences diverse immune functions.
Suppression of SOS repair in E. coli: possible mechanism of antimutagenicity and protective effects of common vegetables

Abstract This study aims to understand variations in antimutagenic potential of vegetables, as observed in reduction of UV-induced mutation (RifS→RifR) in Escherichia coli cells. On further investigation, the juice of vegetables [eggplant (small-violet), pepper (hot Arbol), bean (French), and tomato] was found to suppress mutagenic SOS response as measured by cell filamentation, LexA degradation, and induction of defective prophage as per their antimutagenic potential. Cell filamentation which was observed in 25 and 60% of the UV- and gamma-induced cells, reduced to 2–8%, and 3–16%, respectively in the presence of the vegetable juice; moreover, LexA was also not significantly affected. Phage induction frequency reduced upto 76% compared to control UV-exposed cells. The antimutagenic effect was found to be partially dependent on recB, ruvB gene functions, and was independent of uvrA function. Phenolic compounds were found to be the major contributors to the observed antimutagenicity.
China's Institutional Impediments to Productivity Growth

The objective of this paper is to use a productivity approach to understand the institutional problems that may obstruct China’s future growth. There have been numerous examples to show that, despite a series of reforms over the past three decades, the government still heavily intervenes in the Chinese economy (Wu, HX 2008). Nonetheless, unlike in the planning period that relied on centralised, comprehensive and mandatory controls through state ownership, local governments have been playing an important role in the reform era under a ‘regionally decentralized authoritarian’ regime (Xu 2011). The driving force is competition among localities over growth. Since local GDP growth is used by upper authorities to assess political performance, local government officials are highly motivated to engage in a growth tournament with their peers in other localities (Li and Zhou 2005). Consequently, their restless search for new growth engines has resulted in increasing government interventions in resource allocation and business decisions (Wu and Shea 2008; Xu 2011; Huang 2012).
A genetic history of Italy

Statistical techniques for displaying the geographical distribution of many genes in few synthetic images have been used to represent the various patterns of gene frequencies in Europe and in the world (Menozzi et al. 1978; Piazza et al. 1981a). It has also been shown that such synthetic displays are particularly useful in detecting clines of genetic differentiation associated with movements of populations like those accompanying the Neolithic expansion of farmers from the Near East or, in more recent times, the putative diffusion of Indo‐European‐speaking populations (Ammerman & Cavalli‐Sforza, 1984; Gimbutas, 1973).
Design of Sampling-Based Downconversion Stage for Multistandard RF Subsampling Receiver

This paper presents an improved sampling-based downconversion topology design for multi-standard RF subsampling receiver. Wideband RF receiver architecture is proposed for multimode processing with high-level integration. By an appropriate choice of subsampling frequency complete multistandard RF bands are downconverted to IF domain. Baseband downconversion is achieved by a second subsampling stage. Original results are presented for the analogue IF bandpass anti-aliasing filter design by addressing optimization of sampling frequencies choice adapted to GSM, UMTS and IEEE-802.11g multistandard radio receiver. ADS simulation results are presented to evaluate designed subsampling downconversion stage performances.
Analisis Dampak Migrasi Internal terhadap Upah Pekerja Berdasarkan IPM Provinsi di Indonesia

Penelitian ini bertujuan untuk menganalisis dampakmigrasi internal terhadap upah pekerja berdasarkan tingkat HDI antar provinsi di Indonesia. Masalah mengenai ketimpangan upah di Indonesia muncul antara provinsi yang memiliki tingkat IPM tinggi dan provinsi yang memiliki tingkat IPM rendah. Masalah tersebut mengindikasikan bahwa adanya masalah alokasi SDM di Indonesia. Salah satu instrument regional wage equilibrating adalah migrasi internal. Dengan menggunakan variable IPM sebagai proxy mutu modal manusia, penelitian ini bertujuan mengetahui dampak migrasi internal terhadap upah berdasarkan tingkat IPM provinsi di Indonesia. Menggunkana data SAKERNAS, SP dan SUPAS tahun 1995-2010 dengan metode panel fixed effect. Hasilnya menunjukkan adanya hubungan yang signifikan dari migrasi internal terhadap upah berdasarkan tingkat IPM per provinsi di Indonesia
Genetic control of the antibody response to simple haptens in congenic strains of mice.

The antibody response to the 2,4,6-trinitrophenyl hapten (TNP) conjugated to mouse serum albumin (MSA) was found to be substantially regulated by products of alleles of the H-2 locus. Mice from each of five strains representing congenic pairs differing at the H-2 and H-3 loci and their F1 and F2 progenies were tested. These mice were immunized with a variety of haptens coupled to MSA and their antibody responses were determined after individual serial bleedings by a sensitive test for antigen-binding capacity. The A/Jax and B10.A (H-2a) strains regularly showed a low antibody response whereas their congenic partners, A.BY and C57BL/10 (H-2b) gave a markedly higher response to TNP at all times tested. F1 hybrid progeny gave a low response similar to the H-2a parent strain. The antibody responses of F2 mice were consistent with the segregation of the histocompatability alleles as determined by skin transplants. These results support the hypothesis that low antibody responsiveness to the TNP hapten is determined by the H-2a allele as a dominant trait, whereas homozygosity for the H-2b allele leads to high responsiveness even on diverse strain backgrounds.
The Effect of Internal Audit on the Performance of Decentralized Entities in Rwanda

This research entitled “the effect of internal audit on the performance of decentralized entities in Rwanda, case study of NYABIHU District, Period of 2014-2016”. The specific objectives were to identify the determinants of internal audit of Nyabihu District, to assess the performance indicators of Nyabihu District and to establish the relationship between internal audit and performance of Nyabihu District. The researcher tested the following hypotheses: Control, risk management, determining level of compliance, assurance services, detecting errors and frauds are determinant of internal auditors in Nyabihu District, Effective and efficient operations, financial efficiency and accountability are performance indicators of Nyabihu District and there is a close relationship between internal audit and performance of Nyabihu District. During the whole research process, both primary and secondary data have been used. Primary data were directly obtained from responses provided by the 20 employees of Nyabihu District selected from 60 populations. To attain the purpose of the study through the questionnaires and interview. Secondary data were obtained through literature in the existing books related to this study, academic papers, reports and internet. From the findings, it was revealed that that 100% of the respondents are on positive side agreed that the determinant of internal audit are risk management, control system and determining level of compliance while 20% of respondents not agreed with detecting errors and frauds. The results showed that the indicators of performance in NYABIHU District are financial efficiency as evidenced with 80% efficient operations with 75%, accountability with70 % and goals attained with 60% of respondents. Findings showed that there is indeed a strong positive relationship between internal audit and performance at a Pearson correlation coefficient of r = 0. 732 and p = 0.01. Since r > 0.1, this implies that internal audit affects performance by 75.2% and 26.8% by other factors. From the discussion of findings, we can conclude that the quality of audit work has a significant positive effect on performance of decentralized entities. The recommendations were provided stating that the recruitment systems should be streamlined so that recruitment is done of employees who are qualified in their respective areas regardless of their political affiliation and the government of Rwanda should creates the chartered institute of auditing for growing up the professional auditor with for better function of audit.
Estimating Error Rates in Bioactivity Databases

Bioactivity databases are routinely used in drug discovery to look-up and, using prediction tools, to predict potential targets for small molecules. These databases are typically manually curated from patents and scientific articles. Apart from errors in the source document, the human factor can cause errors during the extraction process. These errors can lead to wrong decisions in the early drug discovery process. In the current work, we have compared bioactivity data from three large databases (ChEMBL, Liceptor, and WOMBAT) who have curated data from the same source documents. As a result, we are able to report error rate estimates for individual activity parameters and individual bioactivity databases. Small molecule structures have the greatest estimated error rate followed by target, activity value, and activity type. This order is also reflected in supplier-specific error rate estimates. The results are also useful in identifying data points for recuration. We hope the results will lead to a more widespread awareness among scientists on the frequencies and types of errors in bioactivity data.
West Asian students' experience with infrastructural facilities and services in selected public Universities in Malaysia

The purpose of this research is to survey the satisfaction level of West Asian students with the facilities and services provided in the five selected public universities in Malaysia. The randomly selected sample involves 262 students from five selected public universities in Malaysia, that is, Universiti Kebangsaan Malaysia (UKM), Universiti Malaya (UM), Universiti Sains Malaysia (USM), Universiti Putra Malaysia (UPM) and International Islamic University Malaysia (IIUM). Focus in this research is on West Asian students who study in these public universities. Further, comparison is made between UKM,UM,USM,UPM and IIUM. Data is collected using questionnaire and analysed using software Statistical Packages For Social Sciences (SPSS). The outcome of research data analysis obtained shows the level of satisfaction of West Asian students with the facilities and services provided by the public universities is average with the highest mean score at 3.00 for UPM. It is hoped that research outcome may guide the management of public universities to improve or restore and upgrade the existing facilities.
Serum anti-beta2-glycoprotein-I and anticardiolipin antibodies during thrombosis in systemic lupus erythematosus patients.

PURPOSE Antibodies to beta2-glycoprotein-I are more strongly associated with clinical antiphospholipid syndrome than are anticardiolipin antibodies. We previously found a decrease in anticardiolipin antibodies at the time of thrombosis in 6 patients with systemic lupus erythematosus (SLE). We therefore sought to determine the prevalence and levels of antibodies to beta2-glycoprotein-I and to cardiolipin before, during, and after thrombosis in patients with SLE, and to compare them with patients who did not have thrombosis. METHODS We studied 24 patients with SLE who had at least one episode of thrombosis and 102 patients with SLE without thrombosis. Serum anticardiolipin antibodies were measured by conventional enzyme-linked immunosorbent assay (ELISA) using newborn calf serum as the blocking agent. Serum anti-beta2-glycoprotein-I antibodies were measured by ELISA on nonirradiated plates, using purified human beta2-glycoprotein-I without phospholipid. RESULTS All patients with thrombosis had anti-beta2-glycoprotein-I antibodies, compared with only 17% of controls (P <0.0001). We observed a significant decrease in serum anti-beta2-glycoprotein-I levels at the time of thrombosis, as compared with previous and subsequent samples. The prevalence and levels of IgG and IgM anticardiolipin antibodies were similar in patients with and without thrombosis. A decrease in IgG or IgM anticardiolipin titers occurred during thrombosis in 6 patients. Anticoagulant, corticosteroid, and immunosuppressive treatments did not appear to affect anti-beta2-glycoprotein-I levels at the time of thrombosis. CONCLUSION Anti-beta2-glycoprotein-I antibodies are strongly associated with thrombosis in patients with SLE. The decrease of anti-beta2-glycoprotein-I levels at the time of thrombosis may indicate a pathogenic role. This antibody may also be a marker of predisposition for thrombosis in these patients.