Miracle-dz/UniFAR-FTUs huggingface dataset:
The Electronic Community Park Audit Tool (eCPAT): Exploring the Use of Mobile Technology for Youth Empowerment and Advocacy for Healthy Community Policy, Systems, and Environmental Change

Empowering and engaging youth in advocacy and participatory action research (PAR) for healthy community environments is an emerging approach to reducing the childhood obesity epidemic. Technology is a promising strategy for engaging youth in such efforts. The Community Park Audit Tool (CPAT) is user-friendly tool for evaluating the ability of parks to promote youth physical activity. Recently an electronic version of the tool (eCPAT) was developed and validated. The purpose of this study was to explore the use of eCPAT mobile technology on youth empowerment and advocacy. This study examined tool usability, youths' technology access, use, and readiness for PAR efforts, effectiveness of mobile technology on youth empowerment and advocacy, interaction effects between tool format and regular technology use, and tool format preferences. Youth ages 11–18 years were recruited and randomized into one of three study conditions: Control (no audit), paper (CPAT), and mobile technology (eCPAT). Intervention youth completed two park audits using assigned format. A subsample of youth in the Control group completed both CPAT and eCPAT audits for comparison. Independent samples t-tests and MANCOVAs explored differences in post-project levels of tool usability and empowerment and advocacy scores between groups. Multivariate linear regression analysis explored the interaction between Control, Paper, or eCPAT group membership and mean technology use in predicting empowerment and advocacy. Youth (n = 124) completed pre and post surveys. The majority of youth had access to technology (smartphone 77.4%, tablet/iPad 67.7%). Youth used mobile technology at least once a day to use apps (M = 7.8, SD = 3.2), browse the web (M = 6.3, SD = 3.3), and search for information (M = 6.3, SD = 3.5). Youth were also ready and willing to use technology for PAR (M = 3.42–3.59). No main or interaction effects were found for post-project levels of youth empowerment or advocacy. However, the eCPAT tool had high usability scores, was better liked, and was preferred by youth over paper-pencil methods. Mobile technologies are ubiquitous and a preferred strategy among youth for engagement in community change. Future studies should explore mobile technology as a potential strategy for engaging youth in ongoing PAR efforts to achieve successful engagement and advocacy in community healthy environmental change.
How does carer resilience change over time and care status? A qualitative longitudinal study

Abstract Objectives: Little research examines trajectories of carer resilience or the factors that facilitate or hinder resilience over time. We use qualitative longitudinal methods to examine trajectories of resilience and which assets and resources are associated with resilience and care status transitions in spousal dementia carers. Method: Based on an original sample of 23 spousal dementia carers (Donnellan, Bennett, & Soulsby, 2015), we conducted 13 follow-up interviews, including: 5 continuing home carers, 3 former carers (institutionalised), and 5 former carers (widowed). Results: Five participants remained resilient (stable resilient), three remained non-resilient (stable non-resilient) and four participants became resilient (non-resilient to resilient). Only one participant became non-resilient (resilient to non-resilient). Stable resilience was characterised by continuing individual assets and community resources. Carers who became resilient returned to previous resources, or gained new resources. Conclusion: Institutionalisation and widowhood are not always barriers to resilience; spousal dementia carers can remain or even become resilient over time despite deteriorating health, institutionalisation, or death of the care recipient.
The Importance of Ground Plane Size on the LTE Antenna Design for Portable Devices

With the help of bandwidth potential analysis, the influence of the ground plane size on the achievable impedance bandwidth of LTE antenna is comprehensively studied. Various different ground plane sizes that can cover almost all the current portable devices such as mobile phone, PAD, tablet and notebook computer are considered. The variation trend between the ground plane size and the antenna bandwidth potential clearly demonstrates how the ground plane size affects the performance of the LTE antenna. The conclusion drawn in this work is confirmed by a real LTE antenna design and the LTE antenna designs reported in the literature.
Regulation of faecal biomarkers in inflammatory bowel disease patients treated with oral mastiha (Pistacia lentiscus) supplement: A double‐blind and placebo‐controlled randomised trial

There is a keen research upon the effects of nutraceuticals on inflammatory bowel disease. The purpose of this study was to explore the effect of mastiha supplement, rich in bioactive nutraceuticals, in active inflammatory bowel disease. This is a randomised, double‐blind, placebo‐controlled clinical trial. Α total of 60 inflammatory bowel disease patients were enrolled and randomly allocated to mastiha (2.8 g/day) or placebo groups for 3 months adjunct to stable medical treatment. Medical and dietary history, Inflammatory Bowel Disease Questionnaire (IBDQ), Harvey‐Bradshaw index, partial Mayo score, biochemical indices, faecal, and blood inflammatory markers were assessed. A clinically important difference between groups in IBDQ was defined as primary outcome. Inflammatory Bowel Disease Questionnaire score significantly improved in verum compared with baseline (p = 0.004). There was a significant decrease in faecal lysozyme in mastiha patients (p = 0.018) with the mean change being significant (p = 0.021), and significant increases of faecal lactoferrin (p = 0.001) and calprotectin (p = 0.029) in the placebo group. Fibrinogen reduced significantly (p = 0.006) with a significant mean change (p = 0.018), whereas iron increased (p = 0.032) in mastiha arm. Our results show regulation of faecal lysozyme by mastiha supplement adjunctive to pharmacological treatments in active inflammatory bowel disease. An effect secondary to a prebiotic potency is proposed.
A 50W Highly Linear 3-Way Integrated Wideband Doherty PA for Small-Cell Application

This article presents the realization and measurement results of a 50W highly linear 3-way integrated Wideband Doherty P A using LDMOS (laterally diffused metal oxide semiconductor) technology. The efficiency / linearity compromise is highly optimized for a power range from 12 dB OBO (output back-off) to 8 dB OBO for the frequency range from 1800 MHz to 2200 MHz. The proposed 3-way integrated combiner uses Cds (drain-to-source capacitance) absorption method to achieve wideband impedance transformation. Linear gain around 16 dB with efficiency >41 %, raw ACPR (Adjacent Channel Power Ratio) of −40dBc was measured at 12 dB back off. At 8 dB back off, efficiency of 45-49% with a raw ACPR< −35 dBc was measured with WCDMA signal. For the optimized Doherty, the measured AMPM(amplitude-to-phase) values at P3dB level has a minimal spread < 5 deg and consistent shape in a fractional bandwidth of 20%. At 39 dBm Pout, 8 dB OBO, the DPA was corrected to <-55 dBc with 60 MHz ISBW in the band B1, B2, B3. The highly linear performance demonstrates that the designed RFIC presents a suitable candidate for multi-band MIMO application for the selected frequency band from 1800 MHz to 2200 MHz.
QoS-Aware IIoT Microservices Architecture

Data has become a strategic driver for the success of existing IIoT applications particularly in uncovering valuable insights and enabling smarter, faster decision making. A key enabler for harnessing the power of this data and integrating it into IIoT applications is through the use of RESTful APIs and microservices. The problem, however, is that IIoT applications do not take into consideration the dynamism of service-based environments. The Quality of Service (QoS) characteristics of microservices may fluctuate during their lifecycle. We propose a solution to this problem by considering the microservices' QoS properties when integrating microservices in IIoT applications. Using our microservice QoS-aware monitoring scheme, it is then possible to establish an overall assessment of a microservice's behavior in delivering the required functionality.
GPU Accelerated Quantum Virtual Screening: Application for the Natural Inhibitors of New Dehli Metalloprotein (NDM-1)

Quantum mechanical approaches for the massive computation on large biological system such as virtual screening in drug design and development have presented a challenge to computational chemists for many years. In this study, we demonstrated that by taking advantage of rapid growth of GPU-based hardware and software (i.e., teraChem), it is feasible to perform virtual screening of a refined chemical library at quantum mechanical level in order to identify the lead compounds with improved accuracy, especially for the drug targets such as metalloproteins in which significant charge transfer and polarization occur amongst the metal ions and their coordinated amino acids. Our calculations predicted four nature compounds (i.e., Curcumin, Catechin, menthol, and Ferulic acid) as the suitable inhibitors for antibiotics resistance against New Delhi Metallo-β-lactamase-1 (NDM-1). Molecular orbitals (MOs) of the QM region of metal ions and their coordinated residues indicate that the bridged hydroxide ion delocalized the electron over the Zn-OH-Zn group at HOMO, different from MOs when the OH− is not presented in NDM-1. This indicates that the bridged hydroxide ion plays an important role in the design of antibiotics and other inhibitors targeting the metalloproteins.
A Systematic Review of Medication Adherence Thresholds Dependent of Clinical Outcomes

Background: In pharmacotherapy, the achievement of a target clinical outcome requires a certain level of medication intake or adherence. Based on Haynes's early empirical definition of sufficient adherence to antihypertensive medications as taking ≥80% of medication, many researchers used this threshold to distinguish adherent from non-adherent patients. However, we propose that different diseases, medications and patient's characteristics influence the cut-off point of the adherence rate above which the clinical outcome is satisfactory (thereafter medication adherence threshold). Moreover, the assessment of adherence and clinical outcomes may differ greatly and should be taken into consideration. To our knowledge, very few studies have defined adherence rates linked to clinical outcomes. We aimed at investigating medication adherence thresholds in relation to clinical outcomes. Method: We searched for studies that determined the relationship between adherence rates and clinical outcomes in the databases PubMed, EmbaseⓇ and Web of Science™ until December 2017, limited to English-language. Our outcome measure was any threshold value of adherence. The inclusion criteria of the retrieved studies were (1) any measurement of medication adherence, (2) any assessment of clinical outcomes, and (3) any method to define medication adherence thresholds in relation to clinical outcomes. We excluded articles considered as a tutorial. Two authors (PB and IA) independently screened titles and abstracts for relevance, reviewed full-texts, and extracted items. The results of the included studies are presented qualitatively. Result: We analyzed 6 articles that assessed clinical outcomes linked to adherence rates in 7 chronic disease states. Medication adherence was measured with Medication Possession Ratio (MPR, n = 3), Proportion of Days Covered (PDC, n = 1), both (n = 1), or Medication Event Monitoring System (MEMS). Clinical outcomes were event free episodes, hospitalization, cortisone use, reported symptoms and reduction of lipid levels. To find the relationship between the targeted clinical outcome and adherence rates, three studies applied logistic regression and three used survival analysis. Five studies defined adherence thresholds between 46 and 92%. One study confirmed the 80% threshold as valid to distinguish adherent from non-adherent patients. Conclusion: The analyzed studies were highly heterogeneous, predominantly concerning methods of calculating adherence. We could not compare studies quantitatively, mostly because adherence rates could not be standardized. Therefore, we cannot reject or confirm the validity of the historical 80% threshold. Nevertheless, the 80% threshold was clearly questioned as a general standard.
Returning to Social Life: Development of Social Identity for Adolescent and Young Adult Survivors of Leukemia in Korea

Objective: The purpose of this study is to investigate the life experiences and processes that occur as adolescent and young adult leukemia survivors return to social life using grounded theory. Method: This study comprised 14 adolescents and young adults who visited a hospital for follow-up care after treatment of leukemia. We used in-depth interviews to examine the participants’ experiences in returning to social life. The semistructured questionnaire examined “good and bad experiences in returning to social life,” “sources of happiness and stress,” and “strategies for managing stressful events. ” Results: We extracted 6 categories and 21 concepts from the interviews. We grouped the 6 categories into a core category and three phases: “catching up with others,” “discovering myself,” and “planning my future. ” A core category shown through all phases was “fear of recurrence. ” The “catching up with others” phase included themes of “feeling different from others” and “wanting to be like others. ” The “discovering myself” phase included “completing one thing at a time” and “recognizing myself as special. ” The “planning my future” phase included “looking for things I can do. ” Conclusions: Self-esteem was an important issue for adolescent leukemia survivors; negative illness perception affected self-esteem in both adolescents and young adults. It is important for health care providers to develop programs to help adolescent and young adult leukemia survivors to perceive their disease experiences more positively and to take part in social life, including school life.
Annellation of Triazole and Tetrazole Systems onto Pyrrolo[2,3-d]pyrimidines: Synthesis of Tetrazolo[1,5-c]-pyrrolo[3,2-e]-pyrimidines and Triazolo[1,5-c]pyrrolo-[3,2-e]pyrimidines as Potential Antibacterial Agents

Syntheses of several novel 4-chloropyrrolo[2,3-d]pyrimidines (1), 4- hydrazinopyrrolo[2,3-d]pyrimidines (2) and 3-amino-4-iminopyrrolo[2,3-d]pyrimidines (7) and their use in the synthesis of tetrazolo[1,5-c]pyrrolo[3,2-e]pyrimidines (3) and triazolo[1,5-c]pyrrolo[3,2-e]pyrimidines (4) required for biological screening are reported.
The MtrCDE Efflux Pump Contributes to Survival of Neisseria gonorrhoeae From Human Neutrophils and Their Antimicrobial Components

The mucosal inflammatory response to Neisseria gonorrhoeae (Gc) is characterized by recruitment of neutrophils to the site of infection. Gc survives exposure to neutrophils by limiting the ability of neutrophils to make antimicrobial products and by expressing factors that defend against these products. The multiple transferable resistance (Mtr) system is a tripartite efflux pump, comprised of the inner membrane MtrD, the periplasmic attachment protein MtrC, and the outer membrane channel MtrE. Gc MtrCDE exports a diverse array of substrates, including certain detergents, dyes, antibiotics, and host-derived antimicrobial peptides. Here we report that MtrCDE contributes to the survival of Gc after exposure to adherent, chemokine-treated primary human neutrophils, specifically in the extracellular milieu. MtrCDE enhanced survival of Gc in neutrophil extracellular traps and in the supernatant from neutrophils that had undergone degranulation (granule exocytosis), a process that releases antimicrobial proteins into the extracellular milieu. The extent of degranulation was unaltered in neutrophils exposed to parental or mtr mutant Gc. MtrCDE expression contributed to Gc defense against some neutrophil-derived antimicrobial peptides but not others. These findings demonstrate that the Mtr system contributes to Gc survival after neutrophil challenge, a key feature of the host immune response to acute gonorrhea.
Multi-scale variability in neuronal competition

We examine whether a single biophysical cortical circuit model can explain both spiking and perceptual variability. We consider perceptual rivalry, which provides a window into intrinsic neural processing since neural activity in some brain areas is correlated to the alternating perception rather than the constant ambiguous stimulus. The prevalent theory for spiking variability is a chaotic attractor called the balanced state; whereas, the source of perceptual variability is an open question. We present a dynamical model with a chaotic attractor that explains both spiking and perceptual variability and adheres to a broad set of strict experimental constraints. The model makes quantitative predictions for how both spiking and perceptual variability will change as the stimulus changes.
Advance Strong Authentication Strong Integrity (ASASI) Protocol for Low Cost Radio Frequency Identification

Internet of things is one of the emerging concepts in 5G networks. For global connectivity and basic identification of the wireless nodes, the RFID system plays an important role. The RFID systems provide automatic identification of the wireless nodes without the restriction of line of sight. However, security and privacy of the RFID systems are of utmost concern. Many ultralightweight authentication schemes have been proposed for secure communication between the reader and the tag. However, most of them were reported to be vulnerable against various attacks shortly after they were proposed. In this paper, we addressed this research gap and propose a new ultralightweight RFID authentication protocol ASASI (Advance Strong Authentication and Strong Integrity). The proposed protocol is extremely lightweight due to optimized design structure and can withstand against all existing attack models.
Cloud Computing Review: Features And Issues

Cloud computing is an on-demand network selfservice, dynamic power and virtual resources. It provide elasticity, restrictions and interactivity which introduces many new features and issues. This paper will review cloud computing common features and issues mainly in term of security. Security has been selected to be the focus of his paper due to high interest in security form both academics and inducts. This paper has categorized cloud computing feature into three categories i.e. technology, economy, and on-Technology. On the other hand this paper has categorized the cloud computing security issues into five categories i.e. infrastructure, data, access, compliance, and provider. This paper provides researchers and industry an insight about the cloud features and issues that may help them in directing their research and implementation of technologies and provide categorization for loud computing features and issues, which can be expanded while the cloud computing technology advances.
The pathological outcome of ThinPrep Pap tests diagnosed as glandular cell abnormalities alone versus combined glandular and squamous abnormalities

Although the incidence of glandular cell abnormalities (GCA) on cervical cytology is low, the clinical and histologic findings are often significant. A combined diagnosis of squamous intraepithelial lesion (SIL) and GCA indicates concern for either two distinct lesions or single entity. The goal of this study is to evaluate the outcome of the diagnosis of GCA alone or in combination with squamous abnormality (SqA).
Fiber Propagation-Induced Mode Partition Noise in Millimeter-Wave Radio-Over-Fiber Systems

In this letter, we study and demonstrate, for the first time, how chromatic dispersion causes laser mode partition noise at millimeter-wave (mm-wave) frequencies. A 60-GHz radio-over-fiber (RoF) transmission system employing an optical frequency comb is theoretically and experimentally investigated. Chromatic dispersion is a limiting factor in RoF systems, which induces power fading and phase noise on the resultant mm-wave beating carriers. Furthermore, experimental measurements in this letter show that when transmitting optical comb spectrum across kilometers of optical fiber, chromatic dispersion destroys partition noise compensation between modes. Therefore, the beat note carrier suffers from intensity noise impairments that degrade the system performance.
Sign Language Recognition Using Deep Learning on Custom Processed Static Gesture Images

Sign Language detection by technology is an overlooked concept despite there being a large social group which could benefit by it. There are not many technologies which help in connecting this social group to the rest of the world. Understanding sign language is one of the primary enablers in helping users of sign language communicate with the rest of the society. Image classification and machine learning can be used to help computers recognize sign language, which could then be interpreted by other people. Convolutional neural networks have been employed in this paper to recognize sign language gestures. The image dataset used consists of static sign language gestures captured on an RGB camera. Preprocessing was performed on the images, which then served as the cleaned input. The paper presents results obtained by retraining and testing this sign language gestures dataset on a convolutional neural network model using Inception v3. The model consists of multiple convolution filter inputs that are processed on the same input. The validation accuracy obtained was above 90% This paper also reviews the various attempts that have been made at sign language detection using machine learning and depth data of images. It takes stock of the various challenges posed in tackling such a problem, and outlines future scope as well.
Graphene-based Millimeter Wave Spatial Amplitude Modulator With Four Transmission Poles

We present an amplitude controllable spatial modulator, which consists of an artificially constructed metamaterial and a graphene layer, to realize four transmission channels in gigahertz (GHz). The four transmission poles TP<inf>1</inf>, TP<inf>2</inf>, TP<inf>3</inf> and TP<inf>4</inf> are located at 26.5GHz, 29.3GHz, 32.6GHz and 35.9GHz, respectively. By applying a bias voltage between the metamaterial and the ptype silicon layer, more than 60% modulation depth is achieved for TP<inf>1</inf>, TP<inf>2</inf> and TP<inf>3</inf>, the modulation depth for TP<inf>4</inf> is 54.5%. Therefore, the modulator indicates many potential applications for multichannel communication system.
biopsy: a possible approach for cancer screening].

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. [Liquid biopsy: a possible approach for cancer screening]. Alain Thierry, Rita Tanos
Sparse Model Selection of Digital Predistorters Using Subspace Pursuit

This communication presents a new technique for the digital predistortion of power amplifiers (PAs) based on sparse behavioral models. The subspace pursuit algorithm formulation is adapted to work in the nonlinear series framework. Experiments driven on a test bench based on a GaN PA driven by a 15-MHz filter bank multicarrier (FBM C) signal were conducted in order to validate the algorithm. Experimental results in a digital predistortion scenario and the comparison with the orthogonal matching pursuit highlight the enhancement of this pruning method.