Miracle-dz/UniFAR-FTUs huggingface dataset:
Privacy-Preserving Query Log Sharing Based on Prior N-Word Aggregation

Privacy-preserving query log sharing has attracted considerable attention especially after the incident of AOL privacy leakage. Queries and URLs of the query logs reflect user preferences, which can help to increase the quality of personalized services. However, these logs may disclose users' sensitive information, and thus need to be sanitized before publication. The existing solutions focused on how to sample records to satisfy differential privacy guarantee and to hide individual preferences in the sampled query logs by perturbation. However, all of them suffer from leakage in queries and URL access, as well as extra redundancy. In this work, we propose to greedily select samples with high utility and provide privacy guarantee by prior estimation of n-word phrase utility. In the estimation, we utilize novel metrics to conduct differential semantic aggregation and to select the representative in each cluster, which can help to achieve the objective of leaking less privacy and releasing more useful information. Extensive experiments on real-world datasets demonstrate the utility of our solutions without compromising individual privacy, and released query logs have been applied to personalized search.
Widespread programmed cell death in early developing chick optictectum

WE demonstrate that widespread programmed cell death exists in proliferative regions of chicken optic tectum during early development using a sensitive fluorescent ISEL method (FISEL+) and antibody staining for an antigen in dying cells. Several developmental stages from embryonic day (E) 3 to E18 were examined. FISEL+- positive cells were rare before E7 and between E9 to E12. However massive labeling was observed in the ventricular zone (VZ) between stages E7.5 and E8. At this time extensive cellmigration is underway and many labeled cells were found not only in the VZ (premigratory cells) but also in the intermediate zone and tectal plate (migra-tory cells). Many labeled cells were also found in upper tectal laminae at late developmental stages (E15 and E18).
Effect of Glucocorticoid on the Differentiation and Development of Terminal Tubules in the Fetal Rat Submandibular Gland

Glucocorticoids (CORT) are known to promote branching of the epithelial cords during the development of the rat submandibular gland. The aim of this study was to examine the effect of CORT (triamcinolone) on the differentiation of cells forming the terminal tubules in the developing fetal rat submandibular gland and the properties of the secretory granules. Light and electron microscopy showed that the terminal tubules of the glands in the experimental group contained more type III cells, which have been identified as proacinar cells, than those in the control group, whereas the relative number of type I cells, which have been identified as terminal tubule cells, was reduced. Immunoelectron microscopy using an antibody against neonatal submandibular gland secretory protein B (SMGB) revealed the presence of more gold particles over type III cell granules in the experimental group than in the control group. Lectin histochemistry demonstrated more wheat germ agglutinin (WGA)-labeled gold particles over type III cell granules in the experimental group than in the control group. These findings suggest that CORT promote the differentiation of type III cells, and moreover stimulate the production of secretory granules reactive for SMGB and WGA by acting on the terminal tubules of the developing rat submandibular gland.
Blood salvage autotransfusion during transplantation for hepatocarcinoma: does it increase the risk of neoplastic recurrence?

Impact of intraoperative blood salvage autotransfusion (IBSA) on neoplastic recurrence. during liver transplantations for hepatocellular carcinoma (LT‐HCC). Between January 1989 and February 2003, 16 patients received a LT‐HCC without IBSA. This group was compared with 31 patients who received the same surgical procedure during the same period, but with IBSA. Data were prospectively collected. All patients had at least a 1‐year postoperative follow up. Pairing was made according to the size of the largest nodule. The percentage of recurrence observed in the two groups was similar: 6.4% in the IBSA group vs. 6.3% in the group without IBSA. The median amount of transfused salvage blood was 1558 ml. The differences observed between the two groups concerned the Child score which was A in 58% patients of the IBSA group vs. 80% in the other group; the percentage of severe portal hypertension was 55% in the IBSA group vs. 31%; the median number of packed red blood cell units transfused intraoperatively was 7 in the IBSA group vs. 0, and the median number of frozen fresh plasma units transfused intraoperatively was 11 in the IBSA group vs. 4.5. It appears that IBSA, essentially used during the most haemorrhagic transplantations, could be used in the case of HCC because it does not modify the risk of neoplastic recurrence.
Cervical Spondylotic Myelopathy: Diagnosis and Treatment

&NA; The delineation of cervical spondylotic myelopathy as a clinical entity has improved with the development of high‐quality cross‐sectional neuroradiologic imaging. The natural history of this disorder is usually slow deterioration in a stepwise fashion, with worsening symptoms of gait abnormalities, weakness, sensory changes, and often pain. The diagnosis can usually be made on the basis of findings from the history, physical examination, and plain radiographs, but confirmation by magnetic resonance imaging or computed tomography and myelography is necessary. Minimal symptoms without hard evidence of gait disturbance or pathologic reflexes warrant nonoperative treatment, but patients with demonstrable myelopathy and spinal cord compression are candidates for operative intervention. Both anterior and posterior approaches have been utilized for surgical treatment of cervical myelopathy. Anterior decompression frequently requires corpectomy at one or more levels and strut grafting with bone from the ilium or fibula. Multilevel laminectomies were initially used for posterior decompression but now are either combined with fusion or replaced by laminoplasty. Any operative technique requires proper patient selection and demands adequate decompression of the canal to effect neurologic improvement. Perioperative complications can be devastating in this group of high‐risk patients with cervical spondylotic myelopathy, but careful attention to detail, meticulous technique, and experience can result in excellent outcomes.
cONSTRICTION/SPREADING RESISTANCE MODEL FOR ELECTRONICS PACKAGING

k thermal conductivity, W/mK An analytical model is developed for predicting constriction and spreading resistances associated with heat transfer from various electronic components under different modes of cooling. The model assumes a heat source in contact with a larger cold plate which is in turn cooled with a convective heat transfer coefficient specified over the sink surface. Unlike existing models that mostly assume limiting boundary conditions, such as isothermal conditions, at the sink surface, the present solution allows one to accurately determine the constriction and spreading resistances in a plate with a full range of cooling conditions varying from an isothermal condition in one limit to a uniform heat-flux condition in the other limit. Dimensionless expressions in the form of infinite series are provided for computing the average and maximum constriction resistances as a function of relative contact size, plate thickness and the Biot number. The results are compared with published numerical data, and the agreement is excellent over a wide range of parameters typically found in microelectronics applications. r, z T T, t rate of heat transfer, W heat flux at the source surface, W / m2 constriction resist ante, C/ W external resist ante, ‘ c / w material resistance, ‘ c / w cylindrical coordinates, m temperature excess over ambient temperature, ‘C temperature at the source, 0 C plate thickness, m Greek Symbols 7)( dimensionless coordinates, r/b, z/b e dimensionless contact radius, a/b A, empirical parameter given by Eq. (27) An eigenvalue T dimensionless plate thickness, t/b a. dimensionless parameter defined by Eq. (26) a. dimensionless parameter defined by Eq. (21) @ dimensionless constriction resistance
Robotic Strategic Behavior in Adversarial Environments

The presence of robots in areas containing threats is becoming more prevalent, due to their ability to perform missions accurately, efficiently, and with little risk to humans. Having the robots handle adversarial forces in missions such as search and rescue, intelligence gathering, border protection and humanitarian assistance, raises many new, exciting research challenges. This paper describes recent research achievements in areas related to robotic mission planning in adversarial environments, including multi-robot patrolling, robotic coverage, multirobot formation, and navigation, and suggests possible future research directions.
Crystal structure of the ankyrin repeat domain of Bcl‐3: a unique member of the IκB protein family

IκB proteins associate with the transcription factor NF‐κB via their ankyrin repeat domain. Bcl‐3 is an unusual IκB protein because it is primarily nucleoplasmic and can lead to enhanced NF‐κB‐dependent transcription, unlike the prototypical IκB protein IκBα, which inhibits NF‐κB activity by retaining it in the cytoplasm. Here we report the 1.9 Å crystal structure of the ankyrin repeat domain of human Bcl‐3 and compare it with that of IκBα bound to NF‐κB. The two structures are highly similar over the central ankyrin repeats but differ in the N‐terminal repeat and at the C‐terminus, where Bcl‐3 contains a seventh repeat in place of the acidic PEST region of IκBα. Differences between the two structures suggest why Bcl‐3 differs from IκBα in selectivity towards various NF‐κB species, why Bcl‐3 but not IκBα can associate with its NF‐κB partner bound to DNA, and why two molecules of Bcl‐3 but only one of IκBα can bind to its NF‐κB partner. Comparison of the two structures thus provides an insight into the functional diversity of IκB proteins.
Air pollution induced changes in the photosynthetic pigments of selected plant species.

Changes in the concentration of different photosynthetic pigments (Chlorophyll and carotenoids) were determined in the leaves of six tree species exposed to air pollution due to vehicular emissions. The six tree species, which are all economically important because of their being fruit bearers, used for timber fodder and as road side trees on the basis of their air pollution tolerance index. These included Mangifera indica L. , Tectona grandis Linn.f , Shorea robusta Gaertn.f. , Holoptelea integrifolia (Roxb.) Planch, Eucalyptus citridora Hook. Syn. and Mallotus philippinensis Muell-Arg. Reduction in chlorophyll 'a', 'b' and carotenoid was recorded in the leaf samples collected from polluted areas when compared with samples from control areas. The highest reduction in total chlorophyll was observed in Holoptelea integrifolia (Roxb.) (48.73%) Planch whereas, the lowest reduction (17.84 %) was recorded in Mallotus philippinensis Muell-Arg. Similarly in case of carotenoid contents, highest reduction (43.02%) was observed in Eucalyptus citridora, and lowest in Mallotus philippinensis Muell-Arg (19.31%). The data obtained were further analyzed using one-way ANOVA and a significant change was recorded in the studied parameters. These studies clearly indicate that the vehicular induced air pollution reduces the concentration of photosynthetic pigments in the trees exposed to road side pollution.
The Evolution of Strategies for Multiagent Environments

SAMUEL is an experimental learning system that uses genetic algorithms and other learning methods to evolve reactive decision rules from simulations of multiagent environments. The basic approach is to explore a range of behavior within a simulation model, using feedback to adapt its decision strategies over time. One of the main themes in this research is that the learning system should be able to take advantage of existing knowledge where available. This has led to the adoption of rule representations that ease the expression of existing knowledge. A second theme is that adaptation can be driven by competition among knowledge structures. Competition is applied at two levels in SAMUEL. Within a strategy composed of decision rules, rules compete with one another to influence the behavior of the system. At a higher level of granularity, entire strategies compete with one another, driven by a genetic algorithm. This article focuses on recent elaborations of the agent model of SAMUEL that are specifically designed to respond to multiple external agents. Experimental results are presented that illustrate the behavior of SAMUEL on two multiagent predator-prey tasks.
New asymmetrical cascade multicell converter based on optimized symmetrical modules

Due to voltage limitation of available semiconductor switches, multicell converters are required for high-power medium-voltage applications. One of the most significant types of multicell converters is cascade multicell converter categorized into symmetrical and asymmetrical ones. This paper first presents a new symmetrical cascade multicell converter in which the number of switches is optimized. An advantage of the proposed symmetrical cascade multicell converter is that the number of required switches in comparison with the conventional symmetrical cascade multicell converter is decreased 50%. Afterwards, a novel asymmetrical cascade multicell converter constructed by the proposed modules of optimized symmetrical converter is presented. The proposed topologies, both symmetrical and asymmetrical cascade multicell converters, are simulated using PSCAD/EMTDC software and simulation results are presented to validate the effectiveness and advantages of the proposed configurations as well as their control strategy.
Reforming Science: Methodological and Cultural Reforms

Contemporary science has brought about technological advances and an unprecedented understanding of the natural world. However, there are signs of dysfunction in the scientific community as well as threats from diverse antiscience and political forces. Incentives in the current system place scientists under tremendous stress, discourage cooperation, encourage poor scientific practices, and deter new talent from entering the field. It is time for a discussion of how the scientific enterprise can be reformed to become more effective and robust. Serious reform will require more consistent methodological rigor and a transformation of the current hypercompetitive scientific culture.
Requirement for microtubules in new membrane formation during cytokinesis of Xenopus embryos.

In cleaving Xenopus eggs, exposure to nocodazole or cold shock prevents the addition of new plasma membrane to the cleavage plane and causes furrows to recede, suggesting a specific role for microtubules in cytokinesis. Whole-mount confocal immunocytochemistry reveals a ring of radially arranged, acetylated microtubule bundles at the base of all advancing cleavage furrows, from the first cleavage through the midblastula stage. We hypothesize that this novel microtubular structure is involved in transporting maternal stores of membrane in the subcortex to a site of membrane addition near the leading edge of the furrow.
Réseaux Évidentiels pour la fusion de données multimodales hétérogènes : application à la détection de chutes. (Evidential Networks-based heterogeneous multimodal data fusion : application for fall detection)

Ces travaux de recherche se sont deroules dans le cadre du developpement d’une application de televigilance medicale ayant pour but de detecter des situations de detresse a travers l’utilisation de plusieurs types de capteurs. La fusion multi-capteurs peut fournir des informations plus precises et fiables par rapport aux informations provenant de chaque capteur prises separement. Par ailleurs les donnees issues de ces capteurs heterogenes possedent differents degres d’imperfection et de confiance. Parmi les techniques de fusion multi-capteurs, les methodes credibilistes fondees sur la theorie de Dempster-Shafer sont actuellement considerees comme les plus adaptees a la representation et au traitement des informations imparfaites, de ce fait permettant une modelisation plus realiste du probleme. En nous appuyant sur une representation graphique de la theorie de Dempster-Shafer appelee Reseaux Evidentiels, nous proposons une structure de fusion de donnees heterogenes issues de plusieurs capteurs pour la detection de chutes afin de maximiser les performances de detection chutes et ainsi de rendre le systeme plus fiable. La non-stationnarite des signaux recueillis sur les capteurs du systeme considere peut conduire a une degradation des conditions experimentales, pouvant rendre les Reseaux Evidentiels incoherents dans leurs decisions. Afin de compenser les effets resultant de la non-stationnarite des signaux provenant des capteurs, les Reseaux Evidentiels sont rendus evolutifs dans le temps, ce qui nous a conduit a introduire les Reseaux Evidentiels Dynamiques dans nos traitements et a les evaluer sur des scenarios de chute simules correspondant a des cas d’usage varies
Innovationspotenzialanalyse für die neuen Technologien fürdas Verwalten und Analysieren von großen Datenmengen (Big Data Management)

Durch die Digitalisierung von Wirtschaft und Gesellschaft ist ein rasantes Anwachsen von Datenbestanden zu beobachten. In fast allen Unternehmens sowie Wissenschaftsbereichen werden bereits heute schon Unmengen an Daten erzeugt, deren Grose, Erfassungsgeschwindigkeit oder Heterogenitat die Fahigkeiten gangiger Datenbanksoftwareprodukte zur Verwaltung und zur Analyse ubersteigt. Dieses Phanomen, welches unter dem Schlagwort „Big Data“ popularisiert wurde, stellt eine grose Chance fur Unternehmen, Wissenschaft und Gesellschaft dar. Allerdings ergibt sich aufgrund der neuen Komplexitat der Daten und Analysen eine Vielzahl an Herausforderungen technischer, wirtschaftlicher und rechtlicher Natur. Diese Studie analysiert die Chancen und Herausforderungen von Big Data insbesondere im Hinblick auf eine nachhaltige Wettbewerbsfahigkeit Deutschlands.
A short, highly active photoreceptor-specific enhancer/promoter region upstream of the human rhodopsin kinase gene.

PURPOSE Rhodopsin kinase (Rk or GRK1) is a photoreceptor-specific enzyme that mediates adaptation of photoreceptors to light and protects these cells against light-induced injury. This study examined the transcriptional mechanisms that maintain physiologic levels of this essential enzyme in photoreceptors. METHODS The 2.0-kb region flanking the 5' end of the human Rk gene was isolated, mapped, and sequenced. The sequence was fused upstream of the luciferase gene and was tested for promoter activity in retinoblastoma cells by transient transfection. Transcriptionally active segments were identified by deletion and site-directed mutagenesis. Transgenic mice were generated that carried the immediate 5' flanking segment linked upstream of the enhancerless green fluorescent protein (GFP) gene. GFP expression was analyzed by RT-PCR, fluorescence microscopy, and immunohistochemistry. RESULTS Mapping and sequence analysis uncovered a TATA-less promoter with several recognizable elements concentrated proximally. A conserved putative homeodomain response element H1 and a GC- and a GA-rich motif were noted within a 0.11-kb region. Another putative homeodomain binding site, H2, and a stretch of C-rich repeats were present distally. Mutagenesis in conjunction with transient transfection in retinoblastoma cells identified the 0.11-kb region and H1 sequence as the key active enhancer-promoter sequences. The distal sequences were inhibitory. Transgenic mice that carried the 0.11-kb DNA segment with the GFP gene linked downstream showed GFP transcript, fluorescence, and immunoreactivity that were restricted to photoreceptors. CONCLUSIONS The experiments defined a short, highly active photoreceptor-specific enhancer-promoter region upstream of the Rk gene. The H1 element contributed substantially but not exclusively to the transcriptional activity of the region. The findings support a transcriptional basis for photoreceptor-specific expression of Rk.
Mutant IDH1: An immunotherapeutic target in tumors

The discovery of driver mutations in cancers has raised interest in their suitability as immunotherapeutic targets. A recent study demonstrates that a point mutation in isocitrate dehydrogenase 1 (IDH1R132H), expressed in gliomas and other tumors, is presented on human MHC class II and induces a mutation-specific CD4+ antitumor T cell response in patients and a syngeneic tumor model in MHC-humanized mice.
La gramática ubicua, o cómo se miran los textos a través de la gramática

Spencer decia que la gramatica de un idioma es lo ultimo que debia ensenarse, porque es la filosofia del idioma, y un nino no aprende su lengua materna por la definicion del adjetivo, el sustantivo o el pronombre, como no aprendemos a respirar estudiando grabados de los pulmones. Creo que el mejor modo de estudiar un idioma es a traves de textos (literarios). (Tomado de M. E. Vazquez, Borges: imagenes, memorias, dialogos, Caracas: Monte Avila, 1977; apud Bravo y Paoletti (1999:95)).
Modelos de Capital Intelectual y sus indicadores en la universidad pública

En el marco de la gestion del conocimiento se encuentra inmerso un aspecto de alta relevancia, no solo contable, sino tambien productivo y competitivo, el cual es denominado hoy dia Capital Intelectual (C.I, se identificara con esta abreviatura). Dicho elemento ha traspasado la barrera de lo financiero para convertirse en una herramienta altamente utilizada en el medio empresarial y academico de las organizaciones modernas. El presente documento hace un recuento, mediante un constructo teorico y bibliografico de las definiciones y modelos mas conocidos sobre el tema, por medio de la sintesis, la compilacion y la recopilacion documental, para establecer algunos indicadores relevantes en la funcion de la universidad publica colombiana y, de esta forma, plantear un avance en el diseno de indicadores de gestion en la funcion social de la educacion de tercer ciclo o superior, como es llamada en la sociedad.
Dialects in pygmy marmosets? Population variation in call structure

Population variation in primate vocal structure has been rarely observed. Here, we report significant population differences in the structure of two vocalizations in wild pygmy marmosets (Trills and J calls). We studied 14 groups of pygmy marmosets Callithrix (Cebuella) pygmaea pygmaea from five populations in northeastern Ecuador. We analyzed the acoustic structure of Trills and J calls recorded from two adult animals in each group through focal samples. Although individuals and groups within a population differed in call structure, we found consistent structural differences at a population level for Trills and J calls. Pair‐wise comparisons for the two call types point to San Pablo and Amazoonico as the populations that differed the most, whereas Hormiga and Zancudococha showed the least differences. Discriminant function analysis indicates that calls from each population could be classified accurately at rates significantly above chance. Habitat acoustics, social factors and genetic drift may explain interpopulation vocal differences. This is the first evidence of within‐subspecies vocal differences, or dialects, in wild populations of a neotropical primate species. Am. J. Primatol. 71:333–342, 2009. © 2009 Wiley‐Liss, Inc.