Miracle-dz/UniFAR-FTUs huggingface dataset:
Adherence and Acceptability of an Oral Antibiotic Used for the Prevention of Pediatric Urinary Tract Infection in Japan

Urinary tract infection (UTI) is a common health care-associated adverse event and the leading nosocomial complication following pediatric urological surgery. While continuous antimicrobial prophylaxis effectively reduces the risk of UTI following such a surgery, non-adherence is common and represents a distinct clinical entity that is associated with renal scarring. Acceptability is likely to have a significant impact on patient adherence. Herein we used a validated data-driven approach—the ClinSearch acceptability score test (CAST)—to investigate the acceptability of cefaclor, an oral antibiotic widely used for the prevention of pediatric UTI in Japan. Standardized observer reports were collected for 58 intakes of cefaclor 10% fine granules in patients aged from 0 to 17 years. The medicine was classified as positively accepted on the acceptability reference framework. According to the percentage of the prescribed dose taken reported at the end of the treatment, patients exhibited good adherence to this well-accepted medicine. Nonetheless, requirements for greater dosing frequency or poor acceptability in certain patients could affect adherence. Acceptability should be established to ensure patient adherence to medicines used for long-term prophylaxis and consequently guarantee the safety and efficacy of the treatment.
Transmission and replication dynamics of SARS CoV-2. (Covid-19 özel sayi.) [Turkish]

At the end of 2019, there was a sudden outbreak of pneumonia in China, which was reported to be caused by the new type of coronavirus, called SARS-CoV-2 This rapidly spreading virus has caused a public health crisis, and turned into a pandemic in a short time through the infected people traveling outside of China It is believed that bats, which are the reservoir of the new coronavirus and provides a gene pool for betacoronaviruses, transmitted the SARS-CoV-2 to an intermediate host called pangolin, which in turn transmitted it to humans Although not fully clarified yet, it is currently the most valid hypothesis that pangolin provided a partial S gene mutation to new coronavirus which is transformed into the final SARS-CoV-2 form that can infect humans The epitope-paratope interaction is achieved through the binding of S glycoprotein of SARS-CoV-2 to the ACE2 receptors in the epithelial tissues of the human respiratory system Following its entry into cells, SARS-CoV-2 completes its life cycle consisting of transcription, translation and replication stages, and transfers the next generation of infective virions out of the cell to infect other susceptible cells The viral proteins, which play an important role in the life cycle of SARS-CoV-2, manage the activities of receptor binding specificity, proteolytic activation, endocytosis activity and inhibition of the host's natural immune response, and shape the pathogenesis of the disease in this way The most important factor that distinguishes COVID-19 infection caused by SARSCoV- 2 from other coronavirus infections is believed to be due to the structural and non-structural protein activities of SARS-CoV-2 As a result, the zoonotic coronavirus species, such as SARS-CoV, MERSCoV, and SARS-CoV-2 that have emerged in recent years have caused a significant public health problem Depending on the mutations in coronaviruses, new species are likely to emerge over time Therefore, detailed and ongoing studies on the biology, pathogenesis and epidemiology of coronaviruses are needed
Mechanical Properties of Polypropylene Blended with Esterified and Alkylated Lignin

Lignin does not show miscibility with com- mercial polyolefins. Therefore, industrial waste lignin was modified in two different ways and subsequently blended with commercial polypropylene (PP) up to 25 wt %. A Brabender electronic plasticorder was used for melt mix- ing at 190 � C. The influence of different modifications on the mechanical properties and processing stability was studied for both polymer blends. The blends of PP and lig- nin modified (esterified) with maleic anhydride showed less deterioration in the mechanical properties compared to blends of PP and alkylated lignin with dichloroethane. Intermolecular interactions between the PP matrix and modified lignin were concluded on the basis of indicative values derived from various relevant theoretical models to
Scanning Transmission Electron Microscopy Investigation of Differences in the High Temperature Redox Deactivation Behavior of CePrOx Particles Supported on Modified Alumina

An in-depth structural and analytical investigation of two 25 wt % Ce0.8Pr0. 2O2/d-Al2O3 catalysts, d = 3.5 wt % SiO2, 4 wt % La2O3, is performed aimed at clarifying the origin of the differences in the evolution of their oxygen storage capacity with temperature. Using a combination of transmission and scanning transmission electron microscopy techniques, the fine details of the structural and compositional changes of the two catalysts with reduction temperature has allowed us to establish the role of SiO2 as a stabilizer of the oxygen handling properties of the Ce−Pr mixed oxide phase under high temperature reducing environments. The entire set of data clearly reveals that Pr does not fully mix with Ce during the synthesis of both catalysts, the spatial distribution of this uncombined fraction of Pr loading being in each case very different: as nanosized particles in the catalyst prepared on the SiO2-doped substrate and as a highly dispersed phase in the lanthana modified alumina catalyst. Therefore, SiO2.
C24‐Ceramide Drives Gallbladder Cancer Progression Through Directly Targeting Phosphatidylinositol 5‐Phosphate 4‐Kinase Type‐2 Gamma to Facilitate Mammalian Target of Rapamycin Signaling Activation

The wide prevalence of chemoresistance and compromised early diagnosis of gallbladder cancer (GBC) has led to poor patient prognosis, requiring sustained efforts for the identification of effective biomarkers and therapeutic intervention. Ceramides have emerged as intracellular signaling molecules linked to tumorigenesis and therapeutic response in cancers. However, the clinical relevance of ceramides with GBC has not been investigated.
A Method for the Measurement of the Threshold-Voltage Shift of SiC MOSFETs During Power Cycling Tests

The application of established test routines like power cycling to wide bandgap devices may be not as straightforward as it seems: When power cycling silicon carbide MOSFETs, the original purpose of triggering package related degradations under application-like and accelerated conditions might be influenced by device related changes during the test, such as carrier trapping, which may lead to a shift in the threshold-voltage <inline-formula><tex-math notation="LaTeX">$V_{\mathrm{th}}$</tex-math></inline-formula> and, thus, in the operating point. With the aim to track the <inline-formula><tex-math notation="LaTeX">$V_{\mathrm{th}}$</tex-math></inline-formula> shift during power cycling in order to separate the mechanisms—i.e., to indicate and quantify the different overlapping effects—a novel inline <inline-formula><tex-math notation="LaTeX">$\Delta V_{\mathrm{th}}$</tex-math></inline-formula> measurement approach is proposed, which can be integrated in existing power cycling test benches with only minor adaptions. First power cycling results with <inline-formula><tex-math notation="LaTeX">$\Delta V_{\mathrm{th}}$</tex-math></inline-formula> monitoring reveal a shift in the operating point leading to an early failure detection in conjunction with a <inline-formula><tex-math notation="LaTeX">$V_{\mathrm{th}}$</tex-math></inline-formula> shift.
Visible-Light-Activated Nanoparticle Photocatalyst of Iodine-Doped Titanium Dioxide

A novel class of visible-light-activated TiO2 photocatalysts were prepared by direct hydrolysis of tetrabutyl titanate through iodine-doping. When calcination temperature is at 673 K, these nanoparticles (mean diameter of ∼5 nm) show stronger absorption in the 400−550 nm range with a red shift in the band gap transition and significantly higher photocatalytic activity than pure TiO2 prepared by the same procedure and Degussa P-25 titania nanoparticles in aqueous phenol solution under visible light irradiation (λ > 400 nm). Furthermore, I-doped TiO2 (673 K) still showed pronounced photocatalytic activity under UV and visible light irradiation.
Fluorescence Emission Properties of Polycyclic Aromatic Compounds in Review

Abstract Fluorescence emission behavior of polycyclic aromatic hydrocarbons (PAHs), polycyclic aromatic nitrogen heterocycles (PANHs), polycyclic aromatic sulfur heterocycles (PASHs) and benzofluoranthenes dissolved in organic solvents of varying polarity is reviewed. Measured fluorescence properties are used to divide aromatic solutes into two categories, probe and nonprobe molecules, depending upon whether the molecule's emission intensity ratios vary systematically with solvent polarity. Seventeen polycyclic aromatic hydrocarbon solute probes are identified and possible probe character versus molecular structure correlations are examined. Also discussed are instrumental and chemical artifacts associated with accurate determination of fluorescence emission intensities.
A VALIDATED HPLC-DAD-MS METHOD FOR IDENTIFYING AND DETERMINING THE BIOACTIVE COMPONENTS OF TWO KINDS OF LUOBUMA

A rapid and effective HPLC-DAD-MS method for quantitatively identifying the flavonoids of Apoacynum venetum L and Poacynum hendersonii has been developed. With this method, all the main components were well separated. In Apoacynum venetum L, the main components are chlorogenic acid, hyperoside, isoquercitrin, and 6″-O-malonylhyperoside, while those of Poacynum hendersonii are quercetin3-O-sophoroside, isoquercitrin and 6″-O-malonylhyperoside. The experimental results showed that the developed approach is accurate, reproducible, and applicable for quantifying the bioactive components of Apoacynum venetum L and Poacynum hendersonii.
ECG Scoring for the Evaluation of Therapy-Naïve Cancer Patients to Predict Cardiotoxicity

Simple Summary Due to improved survival upon effective anti-cancer therapies, the management of treatment-related side-effects is of increasing interest and importance. Cardiovascular side-effects of chemo-, targeted- and/or immunotherapies are common and can be harmful. To date, the identification of patients who could experience those cardiovascular side-effects prior to the anti-cancer therapy start is difficult. We show that the use of a simple electrocardiographic (ECG) score can help to predict the occurrence of cardiovascular toxicity of anti-cancer therapies. Abstract Objective: To evaluate a new electrocardiographic (ECG) score reflecting domains of electrical and structural alterations in therapy-naïve cancer patients to assess their risk of cardiotoxicity. Methods: We performed a retrospective analysis of 134 therapy-naïve consecutive cancer patients in our two university hospitals concerning four ECG score parameters: Contiguous Q-waves, markers of left ventricular (LV) hypertrophy, QRS duration and JTc prolongation. Cardiotoxicity was assessed after a short-term follow-up (up to 12 months). Results: Of all the patients (n = 25), 19% reached 0 points, 50% (n = 67) reached 1 point, 25% (n = 33) reached 2 points, 5% (n = 7) reached 3 points and 0.7% reached 4 or 5 points (n = 1 respectively). The incidence of cardiotoxicity (n = 28 [21%]) increased with the ECG score, with 0 points at 0%, 1 point 7.5%, 2 points 55%, 3 points 71% and ≥3 points 50%. In the ROC (Receiver operating curves) analysis, the best cut-off for predicting cardiotoxicity was an ECG score of ≥2 points (sensitivity 82%, specificity 82%, AUC 0.84, 95% CI 0.77–0.92, p < 0.0001) which was then defined as a high-risk score. High-risk patients did not differ concerning their age, LV ejection fraction, classical cardiovascular risk factors or cardiac biomarkers compared to those with a low-risk ECG score. Conclusion: ECG scoring prior to the start of anti-cancer therapies may help to identify therapy-naïve cancer patients at a higher risk for the development of cardiotoxicity.
Peculiarities of Discontinuous Precipitation in the Pb-Sn Alloy

A model of discontinuous precipitation in binary polycrystalline alloys at low temperatures is presented. The proposed approach allows independent determination of the main parameters, including the interlamellar distance, the maximum velocity of the phase transformation front, and the concentration step at this boundary. This is achieved by using a set of equations for: 1) the mass transfer in the moving interphase boundary; 2) the balance of the entropy fluxes at the phase transformation front, and 3) the maximum rate of the free energy release under constraint of entropy balance. Concepts of mobility and linear interrelation between the driving force and velocity are not used explicitly. Comparison of the model calculation with the experimental results for the Pb-Sn system at different supersaturations is provided.
Occurrence, Treatment, and Toxicological Relevance of EDCs and Pharmaceuticals in Water

Over the past decade a great amount of interest has arisen regarding the occurrence and fate of trace organic contaminants in the aquatic environment. Of particular concern are human hormones and pharmaceuticals, many of which are ubiquitous contaminants in conventional municipal wastewater treatment plant effluents when measured with ng/L detection limits. As analytical procedures and bioassay techniques become more readily available and increasingly sensitive, new contaminants will be discovered. The presence or absence of any chemical in a wastewater effluent is essentially a function of analytical detection capability. This poses a unique challenge for drinking water treatment plants intent on the removal of organic contaminants, as complete removal is merely a reflection of reporting limits. The investigation described here sought to determine the occurrence, treatment, and human health relevance of a chemically diverse group of emerging contaminants.
High-temperature characteristics of nylon-11 and nylon-7 piezoelectrics

Abstract : The piezoelectric strain constant, d31, stress constant, e31, and the electromechanical coupling coefficients, k31, of Nylon-11 and Nylon-7 films were measured up to a temperature close to their melting points. They were found to exhibit their highest values and, in addition, excellent thermal stability at temperatures between 100 C and 200 C. Maximum stable values were d312= 14pC/n and e31 = 21 mC/m2 for Nylon-11, and d31 = 17 pC/N and e31 = 27 mC/m2 for Nylon- 7. Corresponding values of k31 were 0.49 and 0.54. Poled and then annealed Nylon samples exhibit little decay of these values even after annealing at 185 C and 200 C for Nylon-11 and Nylon-7, respectively while poly(vinylidene fluoride) samples showed a large decay in response, decreasing to 4.9 pC/N, 11 mC/m, and k = 0.019 after annealing at 175 deg. C. The extraordinary stability of the piezoelectric activity of these Nylon samples was considered to be related to ferroelectric reorientation of the amide groups dipoles followed by closer packing of the hydrogen bonded sheet structure in the crystalline regions after the annealing treatment.
The Influence of Service Quality, Satisfaction, and Trust Towards Customer Loyalty of Bank Nagari Air Haji Subsidiary Branch

The purpose of this research is to analyze the quality of the service, satisfaction, and trust toward customer loyalty. The number of the sample in this research is 202 respondents based on accidental sampling. They are the customers of Bank Nagari Air Haji Subsidiary Branch. The data processing of this research employs smartPLS 3.2. 7 Structural Equation Modeling (SEM) software. The research result shows that the quality of the service contributes positive impact toward customer satisfaction and customer trust. However, the quality of service has no significant impact toward customer trust and customer loyalty. Customer trust also has positive impact and significant toward customer loyalty.
Transition metal ion-doped In2O3 nanocubes: investigation of their photocatalytic degradation activity under sunlight

The objective of this work was to study the effect of transition metal ion doping (1 wt% of Mn, Fe, Co, Ni, and Cu) in indium oxide (In2O3) on its photocatalytic activity to degrade organic dyes, which are considered potential environment pollutants. The transition metal ion-doped In2O3 nanocube photocatalyst was prepared via the hydrothermal method. After understanding the thermal behavior of the as-prepared sample (In(OH)3), it was calcined at 400 °C for 3 h to obtain In2O3. The In2O3 was systematically investigated via FESEM, X-ray diffraction, Raman spectroscopy and UV-vis absorption analysis. Microstructure analysis by FESEM showed that the In2O3 was formed as nanocubes. These nanocubes were formed in a single phase with a cubic crystal structure, while their crystallite size increased from 11 nm to 19 nm when doped with 1 wt% of transition metals, including Mn, Fe, Co, Ni and Cu. The band gap energy for pure In2O3 was determined to be 3 eV, and that for the metal ion-doped In2O3 showed a slight decrease to the lowest value of 2.94 eV. The photoluminescence (PL) decay lifetime was found to be in the range of 28.56 ns to 33.89 ns. Photocatalytic experiments were conducted for the degradation of methylene blue (MB) dye under sunlight irradiation in the presence of the In2O3 nanocubes. Among the five metal ion-doped samples, the Ni ion-doped In2O3 photocatalyst exhibited the highest degradation efficiency of 98% in 270 min of sunlight exposure. The high performance of Ni–In2O3 is due to its highest PL lifetime of 33.89 ns. The complete route for the degradation of MB dye was revealed by identifying the intermediates.
Heavy Metal Contamination in Arable Soils and Vegetables around a Sulfuric Acid Factory, China

This study was designed to investigate heavy metal (Tl, Pb, Cu, Zn, and Ni) contamination levels of arable soils and vegetables grown in the vicinity of a sulfuric acid factory in the Western Guangdong Province, China. Health risks associated with these metals by consumption of vegetables were assessed based on the hazard quotient (HQ). The soils show a most significant contamination of Tl, followed by Pb, Cu, Zn, and Ni. The heavy metal contents (µg/g, dry weight basis) in the edible parts of vegetables range from 5.60 to 105 for Tl, below detection limit to 227 for Pb, 5.0–30.0 for Cu, 10.0–82.9 for Zn, and 0.50–26.0 for Ni, mostly exceeding the proposed maximum permissible level in Germany or China. For the studied vegetables, the subterranean part generally bears higher contents of Tl and Zn than the aerial part, while the former has lower contents of Cu and Ni than the latter. In addition, the results reveal that Tl is the major risk contributor for the local people since its HQ values are mostly much higher than 1.0. The potential health risk of Tl pollution in the food chain and the issue of food safety should be highly concerned and kept under continued surveillance and control.
Computational techniques applied to the study of the oxidation kinetics of iron and molybdenum cyanocomplexes by peroxynitrous acid

The oxidation kinetics of iron and molybdenum cyanocomplexes by peroxynitrous acid were studied by computational techniques. The rate constants of ONOOH decomposition and substrate oxidation were calculated by fitting the experimental data to the solution of the ordinary differential equations mechanism. There is a linear relationship between the rate constants which is solved by varying the initial concentration of one of the reactive species. The rate constants of the steps involved in ONOOH decomposition were also determined following the same procedure and considering a linear relationship between the rate constants. The results are consistent with the values previously found using the conventional method of integration, and they validate the prior steady state assumption. Copyright © 2008 John Wiley & Sons, Ltd.
Computational Investigation of Negative Capacitance Coaxially Gated Carbon Nanotube Field-Effect Transistors

In this article, we present a computational investigation on nanoscale coaxial-gate negative-capacitance carbon nanotube field-effect transistor (NC CNTFET). The proposed nanodevice is endowed with metal–ferroelectric–metal–insulator–semiconductor (MFMIS) structure. The simulation approach is based on solving self-consistently the nonequilibrium Green’s function formalism with the NC FET electrostatics considering ballistic transport conditions. The computational assessment includes the switching performance and short-channel effects (SCEs) in NC CNTFETs. The negative capacitance behavior of the ferroelectric has been found efficient in boosting the performance of nanoscale CNTFETs in terms of subthreshold swing (SS), drain-induced barrier lowering (DIBL), ON-current, current ratio, and intrinsic delay. In addition, we show the capability of MFMIS configuration in improving the current ratio and SS of CNTFETs with ultrascaled gate lengths. The role of the ferroelectric layer thickness in enhancing the NC CNTFET performance is also studied, where improved performance has been recorded using thicker ferroelectric layer. Achieving high ${I} _{ \mathrm{ON}}/{I} _{ \mathrm{OFF}}$ current ratio, sub-kT SS, and improved immunity against SCEs makes the NC CNTFET as a potential candidate for modern CNT-based nanoelectronics.
Hierarchically Structured Sulfur/Carbon Nanocomposite Material for High-Energy Lithium Battery

We report herein a hierarchically structured sulfur−carbon (S/C) nanocomposite material as the high surface-area cathode for rechargeable lithium batteries. A porous carbon with a uniform distribution of mesopores of 7.3 nm has been synthesized through a soft-template synthesis method. The potassium hydroxide activation of this mesoporous carbon results in a bimodal porous carbon with added microporosity of less than 2 nm to the existing mesopores without deterioration of the integrity of the original mesoporous carbon. Elemental sulfur has been loaded to the micropores through a solution infiltration method. The resulted S/C composites with various loading level of sulfur have a high surface areas and large internal porosities. These materials have been tested as novel cathodes for Li/S batteries. The results show that the cyclability and the utilization of sulfur in the Li/S batteries have been significantly improved. The large internal porosity and surface area of the micromesoporous carbon is essentia.
Quality education to succeed the SDGs among college students through the role of learner empowerment and creative self-efficacy to develop innovative work behavior

Preparing the college students to be ready to perform their innovative work behavior optimally is essential, especially in supporting organizational and national innovation for the SDGs’ success. One way is by examining how the students perceive their abilities, potential, and roles in the learning environment. The researchers believe that the relationship between the learner empowerment and innovative work behavior will have a more significant influence when they can also realize the learner empowerment into creative self-efficacy. The research respondents are 539 third semester students or higher from Universitas Indonesia. This quantitative research uses the Innovative Work Behavior Scale, the Learner Empowerment Scale, and the Creative Self-Efficacy Scale. The mediation analysis results show that creative self-efficacy has a partial mediating effect on learner empowerment’s relation to innovative work behavior. The three dimensions of the learner empowerment (meaningfulness, competence, and impact) are also significantly related to the innovative work behavior, with the impact as the strongest correlating dimension. This research can be used as input for developing the learning programs, both curricular and extracurricular, to perform innovative work behavior optimally.