Miracle-dz/UniFAR-FTUs huggingface dataset:
VERSION OF THE MANUSCRIPT : Efficacy of phytogenic feed additive on performance , production and health status of monogastric animals – a review DOI : 10 . 1515 / aoas-2016-0079

The growing concerns of consumers on the use of antibiotic as a growth promoter in livestock feed have fueled the interest in alternative products. In the recent years a group of natural product known as phytogenic has been a focus of several studies. Phytogenics are a heterogeneous group of feed additives originating from plants and consist of herbs, spices, fruit, and other plant parts. These feed additives are reported to have a wide range of activities including antimicrobial, anthelminthic, antioxidant, growth enhancer, and immune modulator. Besides these properties they are also reported to stimulate feed intake and endogenous secretion and enhance production. They include many different bio-active ingredients such as alkaloids, bitters, flavonoids, glycosides, mucilage, saponins, tannins phenolics, polyphenols, terpenoids, polypeptide, thymol, cineole, linalool, anethole, allicin, capsaicin, allylisothiocynate, and piperine. These feed additives have been tested in the form of extracts, cold pressed oils, essential oils in a number of animals but the results are variable. Therefore, their application as Unauthenticated Download Date | 9/7/17 8:07 PM feed additive has been limited, largely owing to their inconsistent efficacy and lack of full understanding of the modes of action. The future of these feed additives depend on the characteristics of herbs, the knowledge on their major and minor constituents, the in-depth knowledge on their mode of action and their value based on the safety to animal and their products. The aim of this review is to summarize on the current knowledge on the use of phytogenic as a feed additive in monogastric animal.
On IP = PSPACE and Theorems with Narrow Proofs

Very recently, it was shown that the class of languages with interactive proofs, IP, is exactly the class PSPACE. This surprising result elegantly places IP in the standard classification of feasible computations. Furthermore, the IP = PSPACE result reveals some very interesting and unsuspected properties of mathematical proofs. In this column, we define the width of a proof in a formal system $\cal F$ and show that it is an intuitively satisfying and robust definition. Then, using the IP = PSPACE result, it is seen that the width of a proof (as opposed to the length) determines how quickly one can give overwhelming evidence that a theorem is provable without showing the full proof.
On necessary conditions for almost global stability

Some potential applications of the density functions to analysis and synthesis of nonlinear control systems have been studied by Rantzer and Parrilo (2000) and Rantzer and Ceragioli (2001). In this work we prove the necessity of the existence of a density function for a globally asymptotically stable dynamical system.
C-Reactive Protein Values and Erythrocyte Sedimentation Rates after Total Hip and Total Knee Arthroplasty

We studied the changes in serum C-reactive protein levels (CRP) and erythrocyte sedimentation rates (ESR) in patients with primary osteoarthritis, who underwent uncomplicated arthroplasty. Of the 28 patients studied, 12 had cementless total hip replacement (THR), and 16 underwent cemented total knee replacement (TKR) with a tourniquet. In both groups serum CRP levels increased rapidly after surgery, peaking on day 2 (THR 23.17 mg/dl, TKR 26.02 mg/dl), and dropping gradually to pre-operative values on day 21 in THR patients and at the end of the second month in TKR patients. ESR peaked on day 5 after operation (THR 100.5 mm/h, TKR 101.3 mm/h), dropping close to pre-operative values at the end of the third month in THR patients and at the end of the ninth month in TKR patients, although, even after a year, ESRs were slightly above their pre-operative values. Serum CRP levels changed more rapidly than ESRs and returned to normal more rapidly. CRP and ESR values tended to be higher in TKR than in THR patients.
Psychiatric symptoms vary with the severity of dementia in probable Alzheimer's disease.

This cross-sectional study examines relationships among the constellation of psychiatric syndromes in Alzheimer's disease (AD) as a function of dementia severity in 1155 patients with probable AD. The frequency of major depression decreased in severe stages, while agitation, aggression, and psychosis were more frequent in late stages. Major depression was associated with anhedonia, sleep disorders, depressed mood, low self-esteem, anxiety, and hopelessness in mild/moderate and severe stages. Agitation was associated with aggression and psychosis in mild/moderate stages, and psychosis was associated with aggression in moderate/severe stages. In addition, there was a constellation of psychiatric symptoms (e.g., anxiety, wandering, irritability, inappropriate behavior, uncooperativeness, emotional lability) associated with agitation, aggression, and psychosis, which varied according to the severity of the dementia, suggesting a progressive deterioration of frontal-temporal limbic structures. Education and race were independently associated with psychosis. However, while education was associated with psychosis in mild/moderate stages, race was associated with psychosis in moderate/severe stages.
Pyrazolo[3,4‐d]pyrimidine Derivatives as COX‐2 Selective Inhibitors: Synthesis and Molecular Modelling Studies

The pyrazolo[3,4‐d]pyrimidine system shows a multitude of interesting pharmacological properties. Owing to the potential anti‐inflammatory activity of 5‐benzamido‐pyrazolo[3,4‐d]pyrimidin‐4‐one derivatives and considering the easy synthesis of this class of compounds, a set of new 5‐benzamido‐1H‐pyrazolo[3,4‐d]pyrimidin‐4‐ones has been prepared in 42‐80% yields by reacting 5‐aminopyrazole‐4(N‐benzoyl)carbohydrazide derivatives and the opportune triethylorthoesters. Compounds 8a, b, 10a–d, and 11a, b revealed a superior inhibitory profile against COX‐2, when compared to that of reference standards NS398 and indomethacin. Molecular modelling studies confirmed the obtained biological results.
Quality of life following organ transplantation

Organ transplantation is a procedure that can save and prolong the life of individuals with end‐stage heart, lung, liver, kidney, pancreas and small bowel diseases. The goal of transplantation is not only to ensure their survival, but also to offer patients the sort of health they enjoyed before the disease, achieving a good balance between the functional efficacy of the graft and the patient's psychological and physical integrity. Quality of life (QoL) assessments are used to evaluate the physical, psychological and social domains of health, seen as distinct areas that are influenced by a person's experiences, beliefs, expectations and perceptions, and QoL is emerging as a new medical indicator in transplantation medicine too. This review considers changes in overall QoL after organ transplantation, paying special attention to living donor transplantation, pediatric transplantation and particular aspects of QoL after surgery, e.g. sexual function, pregnancy, schooling, sport and work.
The Constructionist Approach to Framing: Bringing Culture Back In

This article aims, within the constructionist paradigm, at integrating culture into the framing process. Four characteristics are important for this approach: the distinction between the event, the media content, and the frame; the explicit attention to the reconstruction of frame packages; the relationship between frame packages and cultural phenomena; and the interaction between frame sponsors, key events, media content, schemata, and the stock of frames. An elaborated framing model is presented, and, subsequently, the constructionist approach is compared with priming and agenda setting. Finally, the methodological implications are discussed, in order to develop a strategy to reconstruct frame packages.
CREBH Maintains Circadian Glucose Homeostasis by Regulating Hepatic Glycogenolysis and Gluconeogenesis

ABSTRACT Cyclic AMP-responsive element binding protein, hepatocyte specific (CREBH), is a liver-enriched, endoplasmic reticulum-tethered transcription factor known to regulate the hepatic acute-phase response and lipid homeostasis. In this study, we demonstrate that CREBH functions as a circadian transcriptional regulator that plays major roles in maintaining glucose homeostasis. The proteolytic cleavage and posttranslational acetylation modification of CREBH are regulated by the circadian clock. Functionally, CREBH is required in order to maintain circadian homeostasis of hepatic glycogen storage and blood glucose levels. CREBH regulates the rhythmic expression of the genes encoding the rate-limiting enzymes for glycogenolysis and gluconeogenesis, including liver glycogen phosphorylase (PYGL), phosphoenolpyruvate carboxykinase 1 (PCK1), and the glucose-6-phosphatase catalytic subunit (G6PC). CREBH interacts with peroxisome proliferator-activated receptor α (PPARα) to synergize its transcriptional activities in hepatic gluconeogenesis. The acetylation of CREBH at lysine residue 294 controls CREBH-PPARα interaction and synergy in regulating hepatic glucose metabolism in mice. CREBH deficiency leads to reduced blood glucose levels but increases hepatic glycogen levels during the daytime or upon fasting. In summary, our studies revealed that CREBH functions as a key metabolic regulator that controls glucose homeostasis across the circadian cycle or under metabolic stress.
Charge transfer and OH vibrational frequency red shifts in nitrate-water clusters.

A theoretical study of charge transfer (CT) characteristics in nitrate (NO3(-)) anion-water complexes is presented, together with those for the halides, F-, Cl-, and Br-, for comparison. The relation between the vibrational frequency red shifts of the hydrogen (H)-bonded OH stretches and CT from the anion to the water molecule, established in previous work for the one-water complexes of the halides, is studied for both the one- and six-water nitrate complexes and is extended to the six-water case for the halides. In NO3(-) x H2O, the water molecule receives about as much charge as that in Br- x H2O. In a result consistent with aqueous phase infrared experiments [Bergström, P. A. ; Lindgren, J.; Kristiansson, O. J. Phys. Chem. 1991, 95, 8575-8580], the CT and OH red shift in NO3(-) x 6 H2O are found to be smaller than those for all of the six-water halide complexes, despite the presence of three H-bonding sites. The inability of the nitrate anion to effect substantial CT lies in the preservation of the pi-system being energetically favored over charge localization and enhancement of the strengths of the multiple H-bonds.
Genetics of Heading Time in Wheat (TRITICUM AESTIVUM L.). I. the Inheritance of Photoperiodic Response.

The inheritance of photoperiodic response was studied in crosses involving four spring wheats (Sonora 64, Pitic 62, Justin and Thatcher) and three winter wheats (Blackhull, Early Blackhull and Extra Early Blackhull). The parental cultivars were classified into a photoperiod-sensitive group (Justin, Thatcher, Blackhull and Early Blackhull) and a relatively photoperiod-insensitive group (Sonora 64, Pitic 62 and Extra Early Blackhull) based on their heading response when vernalized and grown under different daylength regimes. -F(1) data indicated that daylength insensitivity is not always dominant over day-length sensitivity and that the dominance relationship with respect to photoperiodic response depends on the alleles present in the parents. The heading patterns after vernalization and growth under short days of F(1), F(2), F(3) and backcross generations of a 4-parent diallel cross involving Justin, Sonora 64, Extra Early Blackhull and Blackhull could be satisfactorily explained on the basis of two major loci with three alleles at each locus. The genotype for each parent was suggested in terms of these loci. Genes with minor effects also influenced the photoperiodic response in a quantitative manner. -Diallel cross analysis of the number of days to heading (log scale) indicated significant additive and dominance genetic variances, a high average degree of dominance for earliness (photoperiod insensitivity) and a preponderance of recessive alleles in the parents acting in the direction of lateness (photoperiod sensitivity). Estimation of the genetic components of variation contained in the generation means of individual crosses (untransformed data) showed that, besides additivity and dominance, epistasis was also an important factor in the genetic control of photoperiodic response in wheat.
Appearance based key-shot selection for a hand held camera

Automatic selection of key-shots is an important step for video data processing. Depending on the purpose, key-shot selection provides user feed back on recorded data, storage reduction and viewpoint selection and it can be used for panoramic image stitching and 3D-reconstruction. In particular, investigating scenes of crime or accidental investigations involves large amount of data, containing information on physical arrangement of objects, details on surface geometry and appearances. This paper proposes an efficient method for automatic selection of key-shot, providing onsite feedback on recorded segments and automatic selection of view-points for 3D-reconstruction. It uses appearance based object and scene modeling for a freely moving, hand held camera. The camera motion is determined on two levels, comparing appearances of local image regions and full 3D reconstruction. On the lower level, the 2D-warp between subsequent video frames is used to determine local change of image appearance and derive a set of motion key frames. These keyframes than are used to determine full 3D motion and to reconstruct objects. Furthermore, key-frames are used for fast indexation and detection of loop closures. Examples for automatic key-frame selection are given for an re-enacted crime scene, and compared to manual selection.
Channel coding and carrier recovery for adaptive modulation microwave radio links

This paper deals with channel coding and carrier recovery design for high-speed adaptive modulation microwave radio transmission sytems. The challenges posed by the microwave channel are discussed and the design trade-offs are analyzed. The proposed flexible adaptive modulation solution employs M-QAM modulations from 4 QAM up to 512 QAM and a high rate LDPC code. The code-rate flexible LDPC code performs within 1 dB away from the pragmatic capacity in AWGN channel. Particular attention is paid to the design of the carrier synchronization algorithm working at the low SNR conditions imposed by the code and the relatively poor local oscillator behavior.
An adaptive approach for n-version systems

In this paper, a modification of classical n-version systems as discussed. We consider an adaptive approach which allows to model and manage different quality levels of the versions. This is achieved by introducing an individual weight factor to each version of the n-version system. This weight factor is then included in the voting procedure, i.e. the voting as based on a weighted counting. Additionally, the extension of this approach to component-based strategies for building the individual versions of the n-version system as considered.
Implications for marine mammals of large-scale changes in the marine acoustic environment

Abstract The amount of underwater sound from ship traffic, commercial, research, and military sound sources has increased significantly over the past century. Marine mammals and many other marine animals rely on sound for short- and long-range communication, for orientation, and for locating prey. This reliance has raised concern that elevated sound levels from human sources may interfere with the behavior and physiology of marine animals. The dominant source of human sound in the sea stems from propulsion of ships. Shipping noise centers in the 20- to 200-Hz band. Frequencies this low propagate efficiently in the sea, and shipping has elevated the global deepwater ambient noise 10- to 100-fold in this frequency band. Baleen whales use the same frequency band for some of their communication signals, and concern has been raised that elevated ambient noise may reduce the range over which they can communicate. Marine mammals have a variety of mechanisms to compensate for increased noise, but little is known about the maximum range at which they may need to communicate. Some of the most intense human sources of sound include air guns used for seismic exploration and sonar for military and commercial use. Human sources of sound in the ocean can disturb marine mammals, evoking behavioral responses that can productively be viewed as similar to predation risk, and they can trigger allostatic physiological responses to adapt to the stressor. Marine mammals have been shown to avoid some human sound sources at ranges of kilometers, raising concern about displacement from important habitats. There are few studies to guide predictions of when such changes start to lower the fitness of individuals or have negative consequences for the population. Although acute responses to intense sounds have generated considerable interest, the more significant risk to populations of marine mammals is likely to stem from less visible effects of chronic exposure.
Recuperación de información: un enfoque práctico y multidisciplinar

Este libro surge de la necesidad de disponer de un material que, con un enfoque eminentemente didactico, permita dar una vision general de la disciplina de la Recuperacion de Informacion, abarcando desde los fundamentos hasta las propuestas de investigacion actuales. La idea es ofrecer al lector los entresijos de un area de conocimiento cuyos avances se trasladan directamente a programas que empleamos todos los dias para diversas tareas cotidianas.
Expression of Lactobacillus brevis IOEB 9809 tyrosine decarboxylase and agmatine deiminase genes in wine correlates with substrate availability

Aims: Lactobacillus brevis IOEB 9809 is able to produce both tyramine and putrescine via tyrosine decarboxylase and agmatine deiminase enzymes, respectively, when cultured on synthetic media. The aims of this study were to assess the expression of L. brevis IOEB 9809 tdc and aguA1 genes, during wine fermentation and to evaluate the effect of substrate availability and pH on tdc and aguA1 expression, as well as on biogenic amine production and L. brevis viability.
Epidemiological Risk Factors in Microscopic Colitis: A Prospective Case–Control Study

Background:The cause of collagenous colitis (CC) and lymphocytic colitis (LC) is unknown and epidemiological risk factors for CC and LC are not well studied. The aim was to evaluate in a case–control study epidemiological risk factors for CC and LC. Methods:In all, 120 patients with CC, 70 with CL, and 128 controls were included. For all cases and controls information was prospectively recorded. A binary logistic regression analysis was performed separately for CC and LC. Results:Independent associations observed with the diagnosis of CC were: current smoking (odds ratio [OR], 2.4), history of polyarthritis (OR, 20.8), and consumption of lansoprazole (OR, 6.4), low-dose aspirin (OR, 3.8), beta-blockers (OR, 3.6), and angiotensin II receptor antagonists (OR 0.20). In the case of LC they were: current smoking (OR, 3.8), associated autoimmune diseases (OR, 8), and consumption of sertraline (OR, 17.5), omeprazole (OR 2.7), low-dose aspirin (OR, 4.7), and oral antidiabetic drugs (OR, 0.14). Conclusions:The consumption of drugs, current smoking, and associated autoimmune diseases were independently associated with the risk of microscopic colitis.
A novel planar dual-band branch line coupler using defect ground structure

A novel planar coupler with Defect Ground Structure (DGS) is proposed for application to the dual-band operation. In the new design, two cross coupling branches are added to the conventional branch line coupler at the middle. They give more flexibility to design for dual-band application. Using the DGS, high impedance microstrip line is implemented easily and the electrical length of microstrip line increases. The two operation frequencies could be designed more closely using high impedance implemented by DGS. For verification purpose, a compact microstrip dual-band coupler applied for TD-SCDMA and WiMax operation was designed, fabricated and measured. Experimental results are in agreement with predicted values.
FACING UP TO THE PROBLEM OF CONSCIOUSNESS

Consciousness poses the most baffl ing problems in the science of the mind. Th ere is nothing that we know more intimately than conscious experience, but there is nothing that is harder to explain. All sorts of mental phenomena have yielded to scientifi c investigation in recent years, but consciousness has stubbornly resisted. Many have tried to explain it, but the explanations always seem to fall short of the target. Some have been led to suppose that the problem is intractable and that no good explanation can be given. To make progress on the problem of consciousness, we have to confront it directly. In this chapter I fi rst isolate the truly hard part of the problem, separating it from more tractable parts and giving an account of why it is so diffi cult to explain. I critique some recent work that uses reductive methods to address consciousness and argue that these methods inevitably fail to come to grips with the hardest part of the problem. Once this failure is recognized, the door to further progress is opened. In the second half of the chapter I argue that, if we move to a new kind of nonreductive explanation, a naturalistic account of consciousness can be given.
Influence of body composition on 5 year mortality in patients on regular haemodialysis.

BACKGROUND Reduction of body mass index (BMI) significantly affects mortality in haemodialysis (HD) patients, but it remains to be determined which of the body components influences mortality. METHODS We examined the whole body composition of 262 HD patients by dual-energy X-ray absorptiometry (DEXA) (age: 60+/-12 years; HD duration 9+/-7 years; male/female: 177/85; diabetics, n=50) and subsequently followed mortality for 5 years. RESULTS Patient age was significantly correlated with limb/trunk lean mass (LTLM) ratio (r=-0.350, P<0.01) and % fat content in whole tissue (r=0.145, P=0.02). There was a significant positive relationship between LTLM ratio and serum creatinine both in males (r=0.404, P<0.01) and females (r=0.267, P=0.01). Diabetic males and females both had a significantly lower LTLM ratio than non-diabetic males (P<0.01) and females (P<0.04). During the 5 years, 65 patients (24.8%) died mainly of cardiovascular diseases and infections. BMI was lower in the expired group than in survivors (P<0.04). LTLM ratio was significantly reduced in the expired group compared with the surviving males (0.629+/-0.097 vs 0.707+/-0.094; P<0.01) and females (0.611+/-0.101 vs 0.651+/-0.078; P<0.01). Cox's proportional hazards analysis revealed that the reduction of LTLM ratio was a significant determinant of death in men (P<0.01), while a lower percentage of fat content of trunk was a significant determinant of death in women (P<0.01). In contrast, BMI did not influence mortality in either sex. CONCLUSIONS Measurements of regional lean and fat mass volumes by DEXA may be useful for predicting death in patients receiving long-term HD.