Miracle-dz/UniFAR-FTUs huggingface dataset:
Chemical Composition, Nutritional Functions, and Antioxidant Activities of Honeys in Africa

Abstract Honey production in Africa is considered an integral part of folk medicine and provides an opportunity for poor rural communities to increase their economic sustainability. In this review, we provide and discuss the data available on the positive nutritional value and health properties of honey harvested from Africa. Besides sugar, honey contains protein and amino acids, with proline which is about 50% of the total amino acids, vitamins, enzymes, some minerals (Na, K, Mg, Ca, Zn, Cu, Mn, Fe, P, S), trace elements (Mn, Ni, Li, F, I, Cl, Sr, Co) and polyphenol compounds. The paper reviewed studies on the use of African honey with anti-inflammatory, antioxidant, antibacterial, antifungal, anti-breast cancer, antidiabetic and antimycotic properties and also its positive effects on infertility (asthenozoospermia), febrile neutropenia and diabetic foot ulcers.
Factors of Cancer-Related Fatigue in Patients with Malignant Diseases

Summary Symptoms of fatigue and exhaustion are considered to be the most common complaints in patients with oncological diseases during and after treatment. The manifestations can be on a physical, cognitive and emotional level. At diagnosis, 40% of patients report fatigue, and this percentage increases to 90% during treatment. However, the exact determinants of fatigue are not yet known. This article is a literary review of the problem of cancer-related fatigue – mechanisms, risk factors, and the impact on the lives of those affected. Literary data on the role of subjective well-being in terms of fatigue and emotional responses of patients with oncological diseases are described. A number of contemporary studies of the combined effect of fatigue and pain on the functioning of oncology patients have been discussed. It is concluded that the symptoms of fatigue, exhaustion and pain are considered the most common complaints in patients with oncologic pathology during and after treatment, whose manifestations may be physical, cognitive and emotional. On the other hand, human health satisfaction is one of the most important predictors of life satisfaction, which contributes significantly to the overall well-being of the patients group discussed.
Particularities of Nursing in Electroconvulsive Therapy

Abstract Electroconvulsive therapy (ECT) has been a controversial topic, both in the general population and in the medical community since its initial implementation in 1938. Despite clinical applications and proven efficacy in psychiatric and neurological pathologies, such as schizophrenia, catatonia, psychotic disorders, depressive episodes, Parkinson’s disease and psychiatric pathological conditions that occurr during pregnancy or childbed, reluctance to apply ECT persists due to the low degree of information and professional training. The purpose of this article is to emphasize the importance of informing the medical team of the specific training in the provision of adequate nursing within the electroconvulsive therapy. These premises make an essential contribution to the smooth running of the therapeutic process. Taking into account the close interpersonal contact that the medical nurses have with the patient through the profession specifics, it is the appropriate framework to inform the patient and the family regarding the need to establish electroconvulsive therapy, the risks, but especially its benefits. In conclusion, there is a need to establish training courses for nurses so as to ensure the functioning of the therapeutic team as a unit.
Norms for Physical Growth of the Full-Term Babies Born from Singleton Pregnancy in Pleven

Summary The aim of the study was to develop the norms for physical growth (birth weight-, birth height- and head circumference- for age) of the full-term babies born from singleton pregnancy in UMHAT „Dr. G. Stranski” – Pleven (total, by gender and gestational age at birth). A cross-sectional study was carried-out in 2017; 1092 live infants born from singleton pregnancy between 38 and 42 weeks were included in the study. We obtained information about three anthropometric measurements (birth weight-, birth height- and head circumference-for age). Data were processed by SPSS v.24. 0. Norm group ranges (3, 5 and 7 groups) were developed for three indicators using percentile methods. Kruskal-Wallis test was used. The mean birth weight- and height-for age were higher for baby boys (P50, 3280 g and 50 cm) compared with baby girls (P50, 3150 g and 49 cm). Baby boys and girls weighed <2570 g at birth fell into the group ,,very slow growth” (P3). A ,,very fast growth” (P97) was found in baby boys weighed >4120 g at birth (vs. >3870 g for baby girls). Norm group ranges allow to identify the newborns with a higher risk and to focus efforts and health resources to them; it should be updated periodically.
Study on the Mechanism of Shugan Xiaozhi Fang on Cells with Non-alcoholic Fatty Liver Disease

Abstract Cells with non-alcoholic fatty liver disease (NAFLD) were studied to determine the mechanism of liver deficiency via the AdipoR2-PPARa pathway. NAFLD cells were randomly divided into a normal control group, blank control group, model group, low dose group, medium dose group, and high dose group. The NAFLD models were established by incubating the cells with linoleic acid (LA) and palmitic acid (PA) (2:1) for 24 h. The test groups were incubated with different doses of Shugan Xiaozhi Fang extract. The pathological changes in cells that accumulated lipids were detected by Oil Red O staining. Malondialdehyde (MDA) and triglyceride (TG) levels were measured. The apoptosis of cells was evaluated by flow cytometry. The levels of AdipoR2, PPARa, CD36, acyl-CoA mRNA, and protein were confirmed by RT- PCR and Western blot. The results of the Oil Red O staining demonstrated that the NAFLD cell model was successfully established. Compared with the model group, the levels of TG and MDA in the groups that received low, medium, and high doses of Shugan Xiaozhi were significantly lower (P<0.01), and a dose effect was evident. In addition, the expression of AdipoR2, PPARa, CD36, acyl-CoA protein, and mRNA in the Shugan Xiaozhi-treated groups was upregulated. Furthermore, the levels of AdipoR2, PPAR, CD36, acyl-CoA protein, and mRNA in all drug treatment groups that were extracted from L-O2 normal human hepatocytes were significantly upregulated (P<0.01). Moreover, the factor pattern of HepG2 human liver carcinoma cells was similar to that of L-O2. The levels of AdipoR, CD36, acyl-CoA, and AdipoR mRNA in the HepG2 low group were increased (P<0.05). AdipoR, PPAR, CD36, and acyl-CoA protein levels and AdipoR mRNA expression were significantly increased in the intermediate dose group and high dose group (P<0.01). Shugan Xiaozhi Fang attenuates hepatic lipid deposition in NAFLD induced by incubating with LA and PA for 24 h, which is associated with the activation of the AdipoR2-PPARα pathway.
Assessing Higher Education Policy in Brazil: A Mixed Oligopoly Approach

Abstract Higher education is increasingly provided by both public and private universities, in particular in the developing world. Considering a mixed oligopoly setting and inspired by the Brazilian context, we explore the relative merits of some frequently used higher education policies in a context where a high-quality public university interacts with a lower-quality private university. We calibrate the model to match relevant values of Brazilian earnings and educational distribution. Subsidising private university tuition fees increases participation, but many high ability students remain excluded, especially if the subsidy is substantial. Affirmative action improves the surplus associated with the public university system, as more high ability individuals attend the public university, but virtually does not increase higher education participation. Although an expansion of public university places induces a reduction in private university fees, total university enrolment grows slowly, and many high-ability individuals cannot obtain a university education.
The relationship between grading and teacher judgment

Abstract This paper presents two studies examining the interrelation of grading and teacher judgment. Study 1 revealed the structure of teacher judgment two teachers and their classes, based on data from long-term ethnographic research. Through inductive analysis of teacher statements about students, four criteria by which teachers judge their students were identified: performance, aptitude, effort, and communicativeness. Using quantitative data from 639 students and 32 teachers, Study 2 explored the relationship between the criteria for teacher judgment identified in Study 1 and the grade assigned to a particular student. Evaluation questionnaires that teachers completed about their students were used. All four criteria identified in Study 1 positively correlated with the grade, but as the multiple linear regression analysis showed, the final grade was most influenced by the category of performance. However, a teacher’s perception of a student’s performance did not always fully align with their performance as measured by a standardized test.
Similarities and Differences between Verbal and Visual Metaphor Processing: an EEG Study

Abstract This EEG study explores similarities and differences between verbal and visual metaphor comprehension processes. The results of the study show that interpreting either a verbal stimulus or a visual stimulus metaphorically activates similar brain areas, but there are significant differences between the two in terms of neural connectivity and resource allocation patterns. A greater intra-hemispheric connectivity was observed during verbal metaphor comprehension as compared to greater inter-hemispheric connectivity during visual metaphor comprehension. Results of our novel method, called µ index, suggested a distinct information processing mechanism for metaphor in verbal and visual modalities. We found that metaphorical interpretations, especially highly creative interpretations, of visual stimuli required allocation of greater resources when compared to highly creative interpretations of verbal stimuli. Overall, these results provide a deeper insight into the multimodal nature of metaphor processing.
Hedonic Pricing Model for Real Property Valuation via GIS - A Review

Abstract Hedonic pricing models in real property valuation have been frequently applied in many research studies and projects since it was introduced by Rosen in 1974. The development of Geographic Information Systems (GIS) in the recent decades has gradually supports the usage of hedonic model in the spatial data pricing model studies. Beside the basic advantages of GIS to position properties in terms of their geographic coordinates, it has the capabilities of dealing with reasonable amount of data, and wide choices of analysis that make it powerful tool to facilitate the building and implementation of the hedonic models within its framework. Many studies have employed GIS in real property valuation in their present work and for the future prediction. This paper reviews the works of literature on the GIS applications in the real property valuation employing the hedonic pricing models.
Immune Negative Regulator TIPE2 Inhibits Cervical Squamous Cancer Progression Through Erk1/2 Signaling

Abstract Tumor necrosis factor (TNF)-α-induced protein-8-like 2, or TIPE2, is a newly found immune negative regulatory molecule. This study further investigated the role of TIPE2 on proliferation and invasion of cervical squamous cancer cells. Expression of TIPE2 was compared in cervical squamous cancer tissues and adjacent normal tissues by Western blot and immunohistochemistry (IHC). Cervical squamous cancer cell lines, SiHa and C33A, were transfected with recombinant plasmid encoding TIPE2 and tested for cytologic characteristics. The impact of TIPE2 on phosphorylation of extracellular signal-regulated kinase (Erk) signaling pathway was also tested by Western blot analysis of key factors. TIPE2 expression was higher in cervical cancer tissues than that in normal tissue. IHC score of tumor tissue was negatively associated with lymphatic metastasis. Over expression of TIPE2 effectively inhibited the proliferation of cervical cancer cells. Wound healing and transwell assay showed that over expression of TIPE2 suppressed cell migration and invasion in vitro. Meanwhile, phosphorylation of Erk1/2 and upstream mitogen-activated protein kinase kinase (MEK) 1/2 was reduced by TIPE2. TIPE2 is negatively related with development of cervical squamous cancer. TIPE2 is an inhibitory factor of proliferation and invasion of cervical squamous cancer cells, probably through inhibiting Erk signaling pathway.
Seleceted Wireless Communication Protocols and their Properties for Use in IoT Systems

Abstract The article is focused on testing selected communication protocols for the Internet of Things. The aim of the experiments was to find a suitable communication protocol to build a smart device of home automation. The recent developments in the field of communication protocols and data processing are providing a new form of constrained communication, while describing how the Things talk to each other in the Internet of Things. With growing number of connected devices in industry and commercial field, there is a need for the devices which can handle the new forms of communication, handle sensors and operate the battery power. The gathered data is either processed on the “edge” of the network or on the cloud platforms. Authors present a comparison of selected newest communication protocols, while reflecting on the results of their experimental testing.
Effects of cold-storage facility characteristics on the virulence and sporulation of Penicillium expansum and the efficacy of essential oils against blue mold rot of apples

Abstract Blue mold rot, caused by Penicillium expansum, is one of the most economically important post-harvest diseases of apple worldwide. The goals of this study were threefold: to evaluate the diversity of P. expansum isolates for mycelial growth, spore production and lesion diameter on apples; to estimate the effects of cold-storage facility conditions on P. expansum population structure; and to investigate the efficacy of three essential oils against P. expansum. The results showed that storage facilities applying fungicides and storing diverse fruit species selected for P. expansum isolates with a larger lesion diameter on apples. In addition, application of fungicides and diversification in stored fruit species significantly select for P. expansum isolates with higher levels of mycelial growth and spore production, respectively. Moreover, the diversity of host species of stored fruit accounted for 38% of the variability observed between storage facilities for the measured fitness parameters in P. expansum isolates and had a stronger effect on P. expansum population structure than fungicide treatment. Essential oils from Mentha pulegium and Syzygium aromaticum significantly decreased mycelial growth and spore production of P. expansum isolates in vitro. Mentha pulegium essential oil also significantly decreased the size of lesions associated with the blue mold rot of apples. Reducing the diversity of stored host species and applying M. pulegium essential oil may be useful in counter-selecting for aggressive P. expansum isolates and reducing losses due to blue mold rot during fruit storage.
Detection of Chromosomal Breaks Induced by Thiacloprid in Human Lypmhocytes and Detection of Double-Strand Breaks Based on γH2AX Histone Phosphorylation

Abstract Thiacloprid, a neonicotinoid insecticide, is widely used to control various species of pests in the current agriculture of today. The potential genotoxic effects of thiacloprid on human peripheral blood lymphocytes were investigated in vitro by chromosome aberrations (CA), and double-strand breaks (DSB), which were detected by the phosphorylation of γH2AX histone. Human peripheral blood lymphocytes were exposed to 30, 60, 120, 240, 480 µg. ml−1 doses for the last 24 and 48 hours of culture. Thiacloprid increased CA at the concentrations of 240, 480 μg. ml−1 (P < 0.05), but these results did not confirm genotoxicity. The mitotic index (MI) was important to us; it served as a basis for the confirmation of the cytotoxicity of this insecticide. During 48 hours of culture, at the concentration of 480 µg. ml−1, its value rapidly decreased (0.42) (P < 0.001), which did not allow us to analyse the results because of the high cytotoxic response.
Radiotherapy and chemotherapy in patients with primary invasive vaginal carcinoma

Methods of radiotherapy and chemotherapy for patients with primary invasive vaginal carcinoma (PIVC) are pre-sented in the paper. Techniques of teleradiotherapy and intracavitary as well as interstitial brachytherapy are discussed. Optimal treatment volume, dose and fractionation schedules are defined. Principles of combining teleradiotherapy with brachytherapy, accor-ding to FIGO stages, are suggested. Spe-cial attention is paid to controversies concerning radiation dose calculation methods and radiobiological equivalent doses delivered from external beam radiotherapy and brachytherapy. The focus is also placed on toxicity and possible differences in treatment results in patients with PIVC, treated with LDR and HDR brachytherapy. The value of radiochemotherapy and palliative chemotherapy in this group of patients is analysed.
Lipoid Pneumonia: A Review

Exogenous lipoid pneumonia is an uncommon condition resulting from aspiration or inhalation of fatlike material, such as mineral oil found in laxatives and various aerosolized industrial materials. These substances elicit a foreign body reaction and proliferative fibrosis in the lung. Because symptoms are absent or nonspecific and the roentrogenographic findings simulate other disease, exogenous lipoid pneumonia is often unrecognized. Yet appropriate historical inquiries and simple laboratory tests can lead to the correct diagnosis. Removal of the offending agent, may lead to improvement in lung function before serious complications develop.
The Nativeness of Breton Speakers and Their Erasure

Abstract I discuss the nativeness of heritage speakers of Breton in the twentieth century. I present a syntactic test designed for Breton that sets apart its native speakers from its late learners, for whom Breton is a second language. Nativeness is revealed by a better tolerance to syntactic overload when sufficient linguistic stress is applied. Both heritage speakers of inherited Breton and early bilinguals whose linguistic input comes exclusively from school answer this test alike, which I take as a sign they are cognitively natives. The syntactic nativeness of children deprived of familial Breton input suggests there is many more young Breton natives among contemporary speakers than previously assumed. Taking stock of these results, I discuss the cultural erasure of Breton native speakers. I compare their cultural treatment with the figure of the ghost. I end by a discussion of the term new speaker.
Analyzing passing networks in association football based on the difficulty, risk, and potential of passes

Abstract This paper investigates the use of network analysis to identify key players on teams, and patterns of passing within teams, in association football. Networks are constructed based on passes made between players, and several centrality measures are investigated in combination with three different methods for evaluating individual passes. Four seasons of data from the Norwegian top division are used to identify key players and analyze matches from a selected team. The networks examined in this work have weights based on three different aspects of the passes made: their probability of being completed, the probability that the team keeps possession after the completed pass, and the probability of the pass being part of a sequence leading to a shot. The results show that using different metrics and network weights leads to the identification of key passers in different phases of play and in different positions on the pitch.
Irrigation Water Use in the Danube Basin: Facts, Governance and Approach to Sustainability

Abstract In this paper we assess the irrigation water use in the Danube Basin, highlight its complexity, identify future challenges and show the relevance for a basin-wide integrative irrigation management plan as part of a more holistic and coherent resource policy. In this sense, we base our integrative regional assessments of the water-food-energy nexus on insights from an extensive review and scientific synthesis of the Danube Basin and region, experimental field studies on irrigation and agricultural water consumption, current irrigation related policies and strategies in most of the Danube countries, and regulatory frameworks on resources at European Union level. We show that a basin-wide integrative approach to water use calls for the evaluation of resource use trade-offs, resonates with the need for transdisciplinary research in addressing nexus challenges and supports integrative resource management policies within which irrigation water use represents an inherent part. In this respect, we propose a transdisciplinary research framework on sustainable irrigation water use in the Danube Basin. The findings were summarized into four interconnected problem areas in the Danube Basin, which directly or indirectly relate to irrigation strategies and resource policies: prospective water scarcity and Danube water connectedness, agricultural droughts, present and future level of potential yields, and science based proactive decision-making.
Discriminating Between Similar Languages Using Large Web Corpora

This paper presents a method for discriminating similar languages based on wordlists from large web corpora. The main beneﬁts of the approach are language independency, a measure of conﬁdence of the classiﬁcation and an easy-to-maintain implementation. The method is evaluated on VarDial 2014 workshop data set. The result accuracy is comparable to other methods successfully performing at the workshop. A tool implementing the method in Python can be obtained from web site http://corpus.tools/ .
Brand versus generic medications: A disease state approach to identify patients’ perceptions and concerns

Background Medication cost does not solely dictate patient preference of brand name or generic medications. However, few studies have been completed to assess the influence of other factors, such as demographics and chronic diseases. Methods Responses were collected from 347 English speaking adults in the United States, age 18 and older, pertaining to demographics, diagnosed conditions, preference and knowledge of brand and generic medications. Results Participants with COPD, epilepsy, and high cholesterol felt that their condition influenced their preference of brand or generic medication more as compared with participants diagnosed with other conditions. If cost was not an issue, then 46% of respondents would prefer the brand name product, while 18% of participants felt their preference depended on the condition that the medication was intended to treat. Roughly one-third of the participants did not fully understand why there are both brand name and generic medications, and education level did not impact comprehension significantly. Conclusion The incentive for generic preference over brand name is primarily due to cost differences. However, improvement of education pertaining to brand/generic equivalency is needed, as some patients still believe brand name medications are superior to generic alternatives for certain disease states.