Miracle-dz/UniFAR-FTUs huggingface dataset:
Corporate Income Taxation and the Corporate Tax Base in the Czech Republic

The article focuses on trends in tax revenue from corporate income tax in the Czech Republic, the development of number of taxpayers; corporate profits tax bases and the interactions between them. It also shows impacts of profit adjustments on corporate tax revenues. The results of the analysis show that it is difficult to explain the variation in the tax base or tax revenue only by one variable, such as the development of the economy, the number of taxpayers and the tax and accounting rules. Dependency between the tax obligation and the number of taxpayers or the tax rate was not confirmed. Only weak dependency exists between changes in GDP and changes in tax, mainly due to fluctuations in taxes in the first half of the nineties of the last century; in the last decade the dependency is stronger. Relatively strong is the relationship between accounting profit of firms and GDP, especially in the last 15 years. For the calculation of the tax base more important than firms profits are changes of profits to tax base and this effect during the economic slowdown increased.
Drug-absorption analysis from pharmacological data. II. Transcorneal biophasic availability of tropicamide.

Following an ophthalmic dose, the mydriatic drug, tropicamide, may traverse the cornea to reach its vicinal sites of action (biophase) directly or indirectly gain access subsequent to its systemic absorption. The latter route of entry into the biophase may be attributed to fluid volume loss and scleral absorption. A means by which the relative quantities of the drug absorbed transcorneally directly into the biophase and indirectly following systemic absorption at any time can be discerned from concomitant measurements of pupillary diameters in drug-treated and untreated eyes is described. However, except at very high dosage, the observed magnitude of effects in the control eye were insufficient for this method to be practical for tropicamide. The determination of the total relative quantities of drug ultimately dissipated from the absorption site by routes other than transcorneal absorption into the biophase was, however, approximated from measurements performed on the treated eye alone. Semilogarithmic plots of the time course of transcorneal drug passage were linear, indicating the biophasic availability of tropicamide to occur through the operation of apparent first-order processes. A comparison of pharmacological and biokinetic parameters characterizing the mydriatic behavior of tropicamide administered in vehicles having a pH of 5.0 and 7.4 is presented.
Lipolysis and oxidation of lipids during egg storage at different temperatures

Wang Q. , Jin G. , Wang N. , Guo X. , Jin Y. , Ma M. (2017): Lipolysis and oxidation of lipids during egg storage at different temperatures. Czech J. Food Sci., 35: 229–235. The aim of this study was to investigate lipolysis and lipid oxidation of stored eggs at different temperatures (4 and 22°C) by evaluating the changes in physicochemical index, lipid profiles, enzymatic activity, and oxidative index. The results showed that the changes in physicochemical index were more significant at 22°C than at 4°C. Weight loss, moisture content, and pH of egg yolk increased significantly (P < 0.05), whereas the yolk index decreased during storage. However, there was no significant difference in lipid profiles between 4 and 22°C storage temperature. The lipid composition analysis demonstrated that lipid hydrolysis took place during egg storage and resulted in a marked decrease of PL and increase of FFA. It was also found that the content of phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI) decreased significantly during storage. The correlation analysis showed that the lipid degradation is significantly positively related to lipase activity (P < 0.05), and the marked changes of lipid fractions are results of both hydrolysis and oxidation. It can be concluded that the egg physicochemical index and lipase activity were greatly influenced by temperature during storage, but the yolk lipid stability was not significantly influenced by storage temperature.
EFFECTS OF TRIPLE CONSTRAINTS ON THE MANAGEMENT OF PROJECTS IN NAIROBI: THE PROJECT MANAGERS’ PERSPECTIVE

Projects are generally undertaken because they are part of plans to meet business goals and charter organizations to new levels of performance. They are however constrained by competing demands and competing priorities within the project environment. The performance of the project, and the project manager, is measured by the degree to which they overcome these constraints to meet project objectives. The project management triple constraints of scope, time and cost are regarded by project managers’ as key the successful management of projects. Despite the much acquired knowledge in project management, history shows a pattern of project underperformance with projects not effectively meeting one or more of these expectations. The study sought to determine the effects of the triple constraints on the management of projects in Nairobi from the perspective of the project manager. The study adopted purposive sampling targeting 30 (30% of population) project managers registered by The Kenya Association of Project Managers and Project Management Institute, Kenya Chapter. The study found no statistically significant effect of the triple constraint elements on the management of projects in Nairobi. The study recommends that project managers should identify other external factors and/or intra-management of the triple constraints including trade-offs that could be influencing the management of projects in Nairobi.
Integrating FPGA/ASIC into cryptographic storage systems to avoid re-encryption

Almost all cryptographic storage systems need re-encryption when revoking users. These systems differ from each other only in the timing of re-encryption. As re-encryption is an expensive operation, it is significant to avoid re-encryption. To avoid re-encryption in cryptographic storage systems, field programmable gate array (FPGA) and application-specific integrated circuit (ASIC) hardware module have been integrated into encrypt-on-disk object store system in this paper, letting private key never leave the hardware module and object key existing only in hardware module in plaintext. Anyone who does not know private or object key, so when revoking users, just needs to modify access control list (ACL) to delete the privileges of the users. To facilitate file sharing and key management, a group is adopted. In the system, almost all computationally expensive cryptographic operations are through FPGA/ASIC hardware module. Once a creator revokes some users, objects do not need re-encryption. How to use ACL and FPGA/ASIC hardware module to authenticate and authorise is also described. And the procedure of object store and the distribution of metadata are detailed. Finally, an encrypt-on-disk object store prototype system is implemented using FPGA in software solution with tested and effective performance.
Interference Alignment Aided by Locally Connected Relays

In this paper, we consider a class of relay networks made up of two partially connected subnetworks. Every subnetwork consists of several relays along with the nearby sourcedestination node pairs being connected to the relays and, is assumed to be fully connected. The two subnetworks are coupled through the so called inter-subnetwork direct links. A linear interference alignment approach exploiting the one-way relaying protocol is applied. The feasibility conditions for interference alignment, i.e., the required numbers of relays in the whole network and in every subnetwork, are investigated. To this end, we develop a graph-based method to model the network topology and introduce the external constraints, from which an upper bound and a lower bound of the minimum required number of relays in a single subnetwork are obtained. Furthermore, we characterize the feasible region for achieving interference alignment in the considered networks using these bounds.
Perspectives of Big Data Analysis for Knowledge Generation in Project Management Contexts

Knowledge generation for Project Management (PM) is a critical modern issue. Projects are a complex, inter-related set of tasks that aim to provide a service or product in a controlled, managed way. In these scenarios, there is a continuous producing of data and information, which is a potential situation for Knowledge Management (KM) interaction. This chapter evaluates aspects and factors on how it is possible to process data and information, in order to generate applicable knowledge to improve project management. A specific consideration is to understand the observation of contexts of huge amounts of data—known nowadays as Big Data—and its potential knowledge generation for project management, as presented in the final study case. A better comprehension on how knowledge management practices, applied to Big Data contexts, can improve project management processes is the main objective in this chapter.
Antihyperglycemic effect of ipragliflozin, a sodium‐glucose co‐transporter 2 inhibitor, in combination with oral antidiabetic drugs in mice

Inhibition of sodium‐glucose cotransporter 2 is a novel strategy for glycemic control in type 2 diabetes mellitus patients. As the mechanism of action of sodium‐glucose cotransporter 2 inhibitors on plasma glucose levels is distinct from that of existing oral antidiabetic drugs, a combination of the two might provide a therapeutic benefit. Here, we investigated the antihyperglycemic effect of ipragliflozin, a selective sodium‐glucose cotransporter 2 inhibitor, alone or in combination with oral antidiabetic drugs in a range of relevant mouse models to analyse the blood glucose‐lowering properties of different drug types based on their mechanism of action. Oral glucose tolerance tests in ICR mice were used to evaluate the effect of ipragliflozin in combination with the insulin secretagogues, glibenclamide or nateglinide. Liquid meal tests in ICR mice and diabetic KK‐Ay mice were used to investigate the combined effect of ipragliflozin with the dipeptidyl peptidase‐4 inhibitor, sitagliptin, and α‐glucosidase inhibitor, voglibose, respectively. Four‐week repeated administration tests in KK‐Ay mice were used to examine the combined effect of ipragliflozin with the insulin sensitizers, pioglitazone and metformin. In all mouse models tested, the combination of ipragliflozin and existing oral antidiabetic drugs lowered blood glucose or glycated hemoglobin levels more than either monotherapy. In conclusion, inhibition of sodium‐glucose cotransporter 2 by ipragliflozin, alone or in combination with existing oral antidiabetic drugs, has a robust effect on blood glucose levels in a range of mouse models of hyperglycemia.
Composite control method for permanent magnet linear motor

An important factor which could hinder its smooth speed response for a permanent magnet linear motor (PMLM) is the inherent force ripple, and how to suppress the force ripple must be taken into account in the design of the system controller. In this paper, a three tier composite control structure is adopted based on the established PMLM model. An adaptive feedforward compensator is designed to eliminate or suppress the effects of the force ripple. Experiments to verify the feasibility of this method, and experimental results show that the application of such adaptive feedforward compensator can significantly improve the response performance of the system.
A Signal- and Transient-Current Boosting Amplifier for Large Capacitive Load Applications

A signal- and transient-current boosting (STCB) circuit is proposed and applied to a single-stage amplifier driving large capacitive loads. The proposed STCB circuit provides gain-bandwidth product (GBW) extension, slew-rate (SR) improvement and gain enhancement to the amplifier, with only slight alterations to the frequency response and transient response of the single-stage amplifier driving large capacitive loads. No on-chip capacitor or resistor is required. The STCB amplifier is fabricated in a commercial 0.18-μm CMOS technology. The active chip area is 0.00705 mm2. The supply is 1.8 V, and the current consumption is 20.3 μA. The capacitive load (CO) ranges from about 4.4 nF to 19 nF. The measured results with a ~ 19-nF load show the small-signal figure-of-merit (FOMS=GBW·CO/power) and the large-signal figure-of-merit (FOML=SR·CO/power) are 150345 MHz · pF/mW and 31213 V/μs·pF/mW, respectively, which correspond to improvements of 1.52 times and 1.36 times, respectively, to the prior art. The achieved phase margin and gain margin are 80.8 ° and 36.3 dB, respectively.
Integrated modeling of an electro-hydraulic servo manipulator using linear graphs

Analysis and design of mechatronic systems require integrated and concurrent tools. This paper presents an integrated mechatronic modeling tool using linear graphs (LG) theory. To demonstrate the capabilities of the presented framework, an integrated model of a complex electro-hydraulic servo manipulator and its governing motion equations in the state space form are presented. It includes a hydraulic power supply unit, a two-stage flapper-nozzle servovalve, a double-acting single-ended hydraulic cylinder, a position transducer (embedded in the cylinder), a controller circuit, and a servo amplifier. The LG model of each subsystem is generated, and the full integrated dynamic model of the system is obtained by assembling the LG model of the subsystems. The control elements, information pathways and modulated source elements (amplifier and position transducer) are also incorporated.
Different power sharing techniques for converter-interfaced DERs in an autonomous microgrid

This paper discusses three different techniques which can be used for power sharing control and adjustment among parallel converter-interfaced distributed energy resources in an autonomous microgrid. This ratio is decided by the distribution network tertiary controller and passed by the microgrid central controller to the primary controllers of each energy resource. In this paper limitations of the first two methods are discussed in detail and the proposed (third) method is designed such that it overcomes the limitations of the other two methods. The studies and discussions are validated for an autonomous microgrid under consideration through PSCAD/EMTDC-based simulations studies.
A Hybrid 4-bit Radix-4 low power Booth Multiplier with high performance

In this paper a circuit for a new high performance and low power Radix-4 Booth Multiplier is presented. The Radix-4 four bit sales space Multiplier is implemented with the aid of the use of distinct power reduction strategies. To layout a 4*four bit multiplier it's miles necessary to design of sub models like sales space Encoder, Partial Product Multiplexer (PP-MUX), half and full Adder circuit distinctive types of electricity reduction strategies is presented. We reduce power and delay in order that sales space Encoder design MGDI (Modified gate diffusion input), Half and Full Adder design using GDI (gate diffusion input), PP-MUX design using Pass Transistor then all these constraint to combine the design hybrid model of 4*4 bit Radix-4 Booth Multiplier. This paper presents an accurate Hybrid topologies of simulating the power dissipation, delay and power delay product (PDP) using different techniques in 45 nm technology with supply voltage is 1 volt.
Scalp dermatomyositis revisited.

1. Argenziano G, Zalaudek I, Corona R, et al. Vascular structures in skin tumors: a dermoscopy study. Arch Dermatol. 2004;140(12):1485-1489. 2. Scope A, Benvenuto-Andrade C, Agero AL, Halpern AC, Gonzalez S, Marghoob AA. Correlation of dermoscopic structures of melanocytic lesions to reflectance confocal microscopy. Arch Dermatol. 2007;143(2):176-185. 3. Barnhill RL, Fandrey K, Levy MA, Mihm MC Jr, Hyman B. Angiogenesis and tumor progression of melanoma: quantification of vascularity in melanocytic nevi and cutaneous malignant melanoma. Lab Invest. 1992;67(3):331-337. 4. Ilias MA, Wardell K, Stucker M, Anderson C, Salerud EG. Assessment of pigmented skin lesions in terms of blood perfusion estimates. Skin Res Technol. 2004;10(1):43-49. 5. Stücker M, Horstmann I, Nuchel C, Rochling A, Hoffmann K, Altmeyer P. Blood flow compared in benign melanocytic naevi, malignant melanomas and basal cell carcinomas. Clin Exp Dermatol. 1999;24(2):107-111. 6. Dhawan AP. Apparatus and method for skin lesion examination. US Patent 5 146 923. 1992. 7. Zouridakis G, Doshi M, Mullani N. Early diagnosis of skin cancer based on segmentation and measurement of vascularization and pigmentation in Nevoscope images. Conf Proc IEEE Eng Med Biol Soc. 2004;3:1593-1596. 8. Shea CR, Vollmer RT, Prieto VG. Correlating architectural disorder and cytologic atypia in Clark (dysplastic) melanocytic nevi. Hum Pathol. 1999; 30(5):500-505. 9. Tannous ZS, Mihm MC Jr, Sober AJ, Duncan LM. Congenital melanocytic nevi: clinical and histopathologic features, risk of melanoma, and clinical management. J Am Acad Dermatol. 2005;52(2):197-203. 10. Velasco P, Lange-Asschenfeldt B. Dermatological aspects of angiogenesis. Br J Dermatol. 2002;147(5):841-852.
Benefits of investing in cycling

Investing in cycling will generate benefits for the whole country, not just those using a bike to get around. Eleven benefits are summarised here which can help solve a series of health, social and economic problems. This report shows how investing in cycling is good for our transport systems as a whole, for local economies, for social inclusion, and for public health.
PERANAN KOPERASI DALAM MENDORONGPEMBANGUNAN KAPASITAS PETERNAK SAPI PERAH UNTUK MENCAPAI SKALA USAHA LAYAK THE ROLE COOPERATIVE IN PUSHING DAIRY CATTLE CAPACITY BUILDING TO RANCHED FEASIBLE SCALE

Research about the role of cooperatives in encouraging the capacity building of dairy farmers to achieve a feasible scale in Tandangsari KSU Pamulihan, Sumedang has been conducted from 2 nd Febuary 2015 until 7 th April 2015 at Cilembu village, Haurngombong village, and Mekarbakti village. The purpose of this research was to examine the role of cooperatives in promoting the capacity building of KSU Tandangsari’s dairy farmers to achieve a worth scale of business and to know about the capacity building that has been done by dairy farmers in KSU Tandangsari to achieve a worth scale of business. This study uses a case study method with descriptive qualitative approach. The data collected through interviews. The Stages of the data analysis included data reduction, data presentation and a conclusion. Based on the results of the study indicated that the role of cooperatives in encouraging farmers to achieve a worth scale of business through the developi ng of the farmers’ knowledge, facilitating financial capital for business development, supplying production materials, milk marketing and pricing policy. However, the main point of the farmers itself was the creativity in search for knowledge and take advantage of oppotunities,
Function of glycoprotein E of herpes simplex virus requires coordinated assembly of three tegument proteins on its cytoplasmic tail

Glycoprotein E (gE) of HSV plays a key role in cell-to-cell spread and virus-induced cell fusion. Here, we report that this function of gE requires the cooperation of tegument proteins UL11, UL16, and UL21. We found that the four proteins come together with very high efficiency to form a complex in transfected cells and in a manner that is regulated and coordinated. In particular, the inefficient interaction of UL16 with each membrane protein (UL11 and gE) observed in pairwise transfections became efficient when other binding partners were present. The significance of these interactions was revealed in studies of viral mutants, which showed that each of these tegument proteins is critical for processing, transport, and biological activity of gE. These findings provide insights into the mechanisms of how gE executes its function and also have implications in understanding HSV assembly and budding.
Centennial‐to‐millennial‐scale periodicities of Holocene climate and sediment injections off the western Barents shelf, 75°N

At the western continental margin of the Barents Sea, 75°N, hemipelagic sediments provide a record of Holocene climate change with a time resolution of 10–70 years. Planktic foraminifera counts reveal a very early Holocene thermal optimum 10.7–7.7 kyr BP, with summer sea surface temperatures (SST) of 8°C and a much enhanced West Spitsbergen Current. There was a short cooling between 8.8 and 8.2 kyr BP. In the middle and late Holocene summer, SST dropped to 2.5°‐5.0°C, indicative of reduced Atlantic heat advection, except for two short warmings near 2.2 and 1.6 kyr BP. Distinct quasi‐periodic spikes of coarse sediment fraction (with large portions of lithic grains, benthic and planktic foraminifera) record cascades of cold, dense winter water down the continental slope as a result of enhanced seasonal sea ice formation and storminess on the Barents shelf over the entire Holocene. The spikes primarily cluster near recurrence intervals of 400–650 and 1000–1350 years, when traced over the entire Holocene, but follow significant 885–/840– and 505–/605‐year periodicities in the early Holocene. These non‐stationary periodicities mimic the Greenland‐10Be variability, which is a tracer of solar forcing. Further significant Holocene periodicities of 230, (145) and 93 years come close to the deVries and Gleissberg solar cycles.
Event-triggered network-based synchronization of complex networks with neutral neural network nodes

This paper focuses on the event-triggered network-based synchronization problem for a class of complex networks with delayed couplings. The dynamic of each node in the considered networks is described by a neutral neural network. The remote master and the complex networks transmit signals mutually through the common communication channels, which include network-induced delays and stochastic fluctuations. An event-triggering scheme is proposed and utilized when the controller transfer signals to the complex networks. A state error system is formulated in which the event-triggering scheme is concerned with. By using Lyapunov method and some properties of Kronecker product, some synchronization criteria are derived to ensure the global mean-square exponential synchronization of state trajectories of the remote master and the coupled dynamic networks. The event-triggered controller design method is further proposed.
Iridium oxide/platinum gray composite coatings on microelectrodes for neural stimulation

The shrinking size of microelectrodes leads to high electrode/tissue interfacial impedance and low charge injection ability. In order to achieve safe, efficient and durable electrode performances, we proposed a layer-by-layer electrodeposition method to modify the bare platinum microelectrodes with nanostructures. Combining the advantages of platinum gray (Pt gray) with iridium oxide (IrOx), herein a low impedance, high cathodic charge storage capacity (CSCc) and high charge injection IrOx/Pt gray microelectrode was fabricated with nanoscale roughness, which was much higher than each simple coating. Furthermore, it demonstrated superior mechanical and electrochemical stability. Morphological tests showed that nanocone-shaped Pt gray provided large area and hence good adhesion for dense IrOx deposition, which was beneficial for long-term mechanical stability of the composite coating.
Observer-based networked predictive control of uncertain systems with multiple distributed delays

This paper studies the design and stability analysis of uncertain networked control systems with multiple distributed delays. An observer-based networked predictive control method is proposed to compensate for the distributed delays in the feedback channels. Sufficient conditions are presented for the stability of the closed-loop networked predictive control systems with random distributed delays. Both the simulation and experiment results of a ball and beam system illustrate the feasibility and effectiveness of the proposed method.