Miracle-dz/UniFAR-FTUs huggingface dataset:
Spatio-temporal urban social landscape transformation in pre-new-urbanization era of Tianjin, China

China’s economic reforms of 1978, which led to the country’s transition from a centrally planned to a market-oriented economy, ushered in a phase of accelerated urbanization. Influenced by the economic transition and taking advantage of its privileged geographic and historic position, Tianjin has seen dramatic changes in its social landscape during the last three decades. Given this context, this study aims at understanding the different urban socio-spatial patterns of Tianjin and their mechanisms in three distinctive economic contexts by adapting both statistical and spatial approaches. Due to increasing population mobility caused by the economic reforms, the urban social landscape of Tianjin has become increasingly multifaceted, characterized by a “one axis, two nuclei” urban morphology. The rise of the Binhai New Area (TBNA) in the southeast is creating a dual-core urban social structure in Tianjin, with its traditional Urban Core located in the center of the city. In terms of the Urban Core’s expansion and population movements southeast toward the TBNA, an asymmetric suburbanization process is evident in Tianjin. Meanwhile, an additional population shift toward Beijing in the northwest is significant during 2000–2010, illustrating the changing relationship between these two neighboring municipalities. By integrating itself with Beijing, Tianjin has not only recovered from under Beijing’s shadow during the centrally planned economy period, but is also benefitting from Beijing in order to flourish.
Between- and within-subject variation in nutrient intake from

ABSTRACI’ In prospective studies ofdiet it is often necessary to know for how many days subjects should record food consumption in order to be able to rank subjects correctly according to their nutrient intakes. Data from six studies-of toddlers, families, schoolchildren, dietitians, pregnant women, and elderly subjects-were analyzed to estimate the number of recording days necessary for energy, 28 nutrients, and the ratio of polyunsaturated to samrated fatty acids (P:S). The most striking finding is that 7 d ofdiet record do not rank subjects with the degree ofaccuracy commonly assumed. For some nutrients, such as iron, zinc, nicotinic acid, and pyridoxine, it may be desirable to record diet over a number of short, separate periods to achieve the number ofdays required. For others, such as copper, retinol, carotene, vitamin B-12, polyunsaturated fatty acids, P:S, and alcohol, alternative methods of assessment based on dietary histories or questionnaires may be more appropriate. Am J C/in Nutr 1989;50: I 55-67.
Hyperspectral Analysis of Columbia Spotted Frog Habitat

Abstract Wildlife managers increasingly are using remotely sensed imagery to improve habitat delineations and sampling strategies. Advances in remote sensing technology, such as hyperspectral imagery, provide more information than previously was available with multispectral sensors. We evaluated accuracy of high-resolution hyperspectral image classifications to identify wetlands and wetland habitat features important for Columbia spotted frogs (Rana luteiventris) and compared the results to multispectral image classification and United States Geological Survey topographic maps. The study area spanned 3 lake basins in the Salmon River Mountains, Idaho, USA. Hyperspectral data were collected with an airborne sensor on 30 June 2002 and on 8 July 2006. A 12-year comprehensive ground survey of the study area for Columbia spotted frog reproduction served as validation for image classifications. Hyperspectral image classification accuracy of wetlands was high, with a producer's accuracy of 96% (44 wetlands) correctly classified with the 2002 data and 89% (41 wetlands) correctly classified with the 2006 data. We applied habitat-based rules to delineate breeding habitat from other wetlands, and successfully predicted 74% (14 wetlands) of known breeding wetlands for the Columbia spotted frog. Emergent sedge microhabitat classification showed promise for directly predicting Columbia spotted frog egg mass locations within a wetland by correctly identifying 72% (23 of 32) of known locations. Our study indicates hyperspectral imagery can be an effective tool for mapping spotted frog breeding habitat in the selected mountain basins. We conclude that this technique has potential for improving site selection for inventory and monitoring programs conducted across similar wetland habitat and can be a useful tool for delineating wildlife habitats.
Lentivirus-mediated expression of VEGF165 in rat hair follicle stem cells

Tissue-engineered skin is the latest most effective treatment for major skin defects, whereas the difficulty of vascularization prevents further development problematic. The purpose of our study was to transfect rat hair follicle stem cells (rHFSCs) with vascular endothelial growth factor-165 (VEGF 165 ) using lentivirus vectors. rHFSCs were harvested from 1-week-old Sprague-Dawly (SD) rats and digested with dispase and collagenase IV. rHFSCs were cultured and their growth curve was plotted. They were then characterized by detecting marker genes with immunofluorescent staining and real-time polymerase chain reaction (RT-PCR). Transfection was performed using either pLV-VEGF 165 -IRES (internal ribosome entry site)-EGFP (enhanced green fluorescent protein) (experimental group) or pLV-IRES-EGFP (blank control). Expression of VEGF 165 mRNA and protein were detected with RT-PCR and western blotting, respectively. The cultured rHFSCs showed typical cobblestone morphology with good proliferative capacity. VEGF 165 was successfully transfected into the cells at 2 weeks at a rate of 85.8±1.9%. Both VEGF165 mRNA and protein were examined in the experimental cells. Therefore rHFSCs can be successfully and effectively isolated with high purity and good proliferative capacity. rHFSCs transfected using lentivirus expressed high levels of VEGF 165 , so are potentially an ideal cell source for tissue-engineered hair follicles, vessels and skin.
Human behavior logging support system utilizing fused pose/position sensor and behavior target sensor information

This paper proposes a behavior log creation support system realized by sensor fusion. The system is equipped with a human pose sensor and a staying room sensor as the pose/position sensors as well as a voice sensor and a PC (personal computer) utilization history sensor to detect the target of the behavior. The human pose sensor classifies human behavior into "standing", "sitting" and "walking". The staying room sensor records a name of a room where the user stays. The voice sensor detects the conversation, which appears when the user is with someone else. The PC utilization history sensor records not only whether a PC is used or not but also the names of the application software to serve as a detector of the behavior target during computer work. The measured data from these sensors is displayed to the user to support the creation of a behavior log, i.e. to support the user to recall and to input contents and targets of his or her behavior. The experiment of making use of the sensors and creating a behavior log proved that the recorded events of the behavior log per all events improved from 60% with no support to more than 90% with support of the system. The result quantitatively shows the capability of human behavior logging support of the system.
An experimental evaluation of the performance of two-branch space and polarization diversity schemes at 1800 MHz

Determines the mean signal level and envelope cross-correlation of 1800 MHz base station signals received in two-branch spatial and polarization diversity schemes. Measurements have been conducted with the experimental base site located in (i) two urban sites, (ii) a residential area, (iii) a rural area, and (iv) near a motorway. In each location, the effect of the random orientation of a typical mobile radio telephone handset has been studied by examining the characteristics of signals received from a mobile collinear antenna inclined at angles of 0/spl deg/, 30/spl deg/, 45/spl deg/, 60/spl deg/, and 90/spl deg/ to the vertical. Furthermore, the diversity gain at 90% signal reliability has been evaluated for each diversity scheme by simulating selection, equal-gain and maximal-ratio combining techniques using the recorded signals as inputs. Results have shown that 20/spl lambda/ separation in the horizontal plane or 15/spl lambda/ in the vertical plane is sufficient to obtain a cross-correlation of less than 0.7 for most of the time at 1800 MHz. Similar cross-correlation results were obtained for polarization diversity. When the antenna is inclined at 45/spl deg/, a 6 dB degradation in signal level was recorded for space diversity schemes. However, the diversify gain is unaffected by tilt and remains unchanged at 5-6 dB for horizontal and 3.5-4.5 dB for vertical separation. For polarization diversity, only a little degradation is experienced because most of the energy lost on the vertical branch is recovered on the horizontal branch. The diversity gain is between 1-2 dB at 0/spl deg/ tilt and increases to 3-5.2 dB at 45/spl deg/. >
Breast Self-Examination: Knowledge and Practice Among Female Textile Workers in Vietnam

Breast self-examination (BSE) is a simple, feasible, and suitable method for breast cancer screening in low–middle setting countries. The aim of this study was to assess the knowledge and practice of BSE among female textile workers in Vietnam. A cross-sectional study was conducted among 1036 female workers, aged 43.9 ± 3.1 years old, who were working in 4 textile enterprises in Hanoi and Ho Chi Minh City, in 2016. Overall, 22.7% of participants showed sufficient knowledge on BSE; 15.2% performed monthly BSE; and 7.7% completely performed all 5 steps of BSE. The prevalence of insufficient BSE knowledge was higher among participants with low level of education (odds ratio [OR]: 1.71; 95% confidence interval [CI]: 1.22-2.39, below vs above secondary school), and those whose husbands were farmers or workers (OR: 1.76; 95% CI: 1.27-2.45, compared to other sectors). This prevalence was, however, negatively associated with receiving information on BSE (OR: 0.16; 95% CI: 0.11-0.23, yes vs no). The prevalence of insufficient BSE practice was also higher among females with husbands who were farmers or workers (OR: 1.67; 95% CI: 1.15-2.43, compared to other sectors). In contrast, it was much lower among participants who had history of breast-related diseases (OR: 0.46; 95% CI: 0.24-0.88, yes vs no), received BSE information (OR: 0.13; 95% CI: 0.08-0.19, yes vs no), and had sufficient overall BSE knowledge (OR: 0.09; 95% CI: 0.06-0.13, yes vs no), compared to those who did not. There was a low prevalence of sufficient BSE knowledge (22.7%) and practice (15.8%) among female textile workers in Hanoi and Ho Chi Minh City. Low level of education and not being provided BSE information were associated with insufficient BSE knowledge and practice among Vietnamese female textile workers. Health education programs are essential to encourage and improve women’s knowledge and practice of BSE.
ALTERATIONS OF MACULAR BLOOD FLOW IN SUPERFICIAL AND DEEP CAPILLARY PLEXUSES IN THE FELLOW AND AFFECTED EYES OF PATIENTS WITH UNILATERAL IDIOPATHIC EPIRETINAL MEMBRANE.

PURPOSE Previous research suggests that proliferation of the idiopathic epiretinal membrane (IERM) is related to microbreaks in the inner limiting membrane, which are caused by posterior vitreous detachment. In this study, we used optical coherence tomography angiography to determine whether a vascular defect in the inner retina is present before the mechanical damage caused by posterior vitreous detachment. METHODS For patients with unilateral IERM (N = 23), optical coherence tomography angiography with blood flow measurement was performed in both eyes at the superficial capillary plexuses (SCP) and deep capillary plexuses (DCP) with 6 mm × 6-mm scans and ETDRS grids centered on the fixation point. These values were then compared with 45 healthy control eyes (CEs). RESULTS The optical coherence tomography angiography data showed that blood flow was lower in the fellow eyes of IERM patients than in CEs when the whole enface macula (SCP: P = 0.031, DCP: P = 0.004) and extramacular area (SCP: P = 0.048, DCP: P = 0.026) were compared between groups. The blood flow was also lower in the affected eyes compared with CEs in both whole en face macula (SCP: P < 0.001, DCP: P < 0.001) and extramacular areas (SCP: P = 0.011, DCP: P < 0.001). CONCLUSION Data from this study revealed that blood flow is significantly reduced in the fellow eyes of patients with unilateral IERM when compared with CEs. Overall, the data suggest that a vascular retinal defect could produce changes in the inner retina, preceding and influencing the formation of microbreaks occurring at the time of posterior vitreous detachment in the inner limiting membrane. Understanding the upstream mechanism of inner limiting membrane microbreaks may provide a therapeutic target aimed to ultimately prevent Mu[Combining Diaeresis]ller cells, astrocyte, and fibroblast migration, which cause IERM proliferation.
MC4R and HNF4α promoter methylation at birth contribute to triglyceride levels in childhood

Although the changes in DNA methylation are assumed to be due to the association between adverse intrauterine conditions and adult metabolic health, evidence from human studies is rare. Little is known about the changes in DNA methylation present at birth that affect metabolic profiles in childhood. Previous studies have shown that the melanocortin 4 receptor (MC4R) and hepatocyte nuclear factor 4 alpha (HNF4α) genes are associated with obesity and metabolic disorders. Thus, we investigated the associations of the DNA methylation statuses of MC4R and HNF4α in cord blood with metabolic profiles in childhood.We collected data from 90 children 7 to 9 years of age included in the Ewha Birth & Growth Cohort Study in Korea. DNA methylation was analyzed by pyrosequencing. The children were split into 2 groups according to the cutoff triglyceride (TG) levels (<110 and ≥110 mg/dL). The methylation statuses of MC4R and HNF4α at birth were significantly associated with the TG level in childhood (P < .05). It was interesting to note that the methylation statuses of MC4R and HNF4α in cord blood were significantly decreased, whereas childhood body mass index was significantly increased, in children with high TG levels compared with children with low TG levels (P < .05). Our findings show that the methylation statuses of MC4R and HNF4α at birth are associated with metabolic profiles in childhood. These epigenetic modifications occurring in early life may contribute to subsequent metabolic-related disorders. Thus, we suggest that DNA methylation status in cord blood may be predictive of the risk of developing metabolic syndrome.
The power of mantis shrimp strikes: interdisciplinary impacts of an extreme cascade of energy release.

In the course of a single raptorial strike by a mantis shrimp (Stomatopoda), the stages of energy release span six to seven orders of magnitude of duration. To achieve their mechanical feats of striking at the outer limits of speeds, accelerations, and impacts among organisms, they use a mechanism that exemplifies a cascade of energy release - beginning with a slow and forceful, spring-loading muscle contraction that lasts for hundreds of milliseconds and ending with implosions of cavitation bubbles that occur in nanoseconds. Mantis shrimp use an elastic mechanism built of exoskeleton and controlled with a latching mechanism. Inspired by both their mechanical capabilities and evolutionary diversity, research on mantis shrimp strikes has provided interdisciplinary and fundamental insights to the fields of elastic mechanisms, fluid dynamics, evolutionary dynamics, contest dynamics, the physics of fast, small systems, and the rapidly-expanding field of bioinspired materials science. Even with these myriad connections, numerous discoveries await, especially in the arena of energy flow through materials actuating and controlling fast, impact fracture resistant systems.
“Choose Today, Live Tomorrow”: A Content Analysis of Anti-Substance Use Messages Produced by Adolescents

Adolescent-produced anti-substance use messaging is an increasingly popular and effective prevention strategy. However, little is known about the content of these messages and the production elements adolescents use to bring that content to life. In this article, we present a content analysis of 95 anti-substance use messages developed by 4-H club members across nine U.S. states as part of their participation in the media literacy program REAL media. Posters and videos were content-analyzed for target substance, prevention goal, message form, message content, persuasion strategies, and production elements. Results of the content analysis revealed that combustible tobacco (smoking) was the most popular target substance in the sample among the choices of alcohol, marijuana, e-cigarettes, and chewing tobacco. More youth developed messages with the goal of preventing substance use, rather than stopping current use. Slogans were used in the majority of messages, and nearly all messages took an informational form, rather than narrative or statistical form. Persuasion strategies covered in the curriculum, including fun with the group, unexpected, style, and endorsement were scantily used. Finally, results showed that production value was high in this sample, reflected by the extensive use of color and variety of fonts and font sizes. Implications for future media literacy interventions and research are discussed.
Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes

Background Excess transmission of pressure pulsatility caused by increased arterial stiffness may incur microcirculatory damage in end organs (target organ damage [TOD]) and, in turn, elevate risk for cardiovascular disease (CVD) events. Methods and Results We related arterial stiffness measures (carotid‐femoral pulse wave velocity, mean arterial pressure, central pulse pressure) to the prevalence and incidence of TOD (defined as albuminuria and/or echocardiographic left ventricular hypertrophy) in up to 6203 Framingham Study participants (mean age 50±15 years, 54% women). We then related presence of TOD to incident CVD in multivariable Cox regression models without and with adjustment for arterial stiffness measures. Cross‐sectionally, greater arterial stiffness was associated with a higher prevalence of TOD (adjusted odds ratios ranging from 1.23 to 1.54 per SD increment in arterial stiffness measure, P<0.01). Prospectively, increased carotid‐femoral pulse wave velocity was associated with incident albuminuria (odds ratio per SD 1.28, 95% CI, 1.02–1.61; P<0.05), whereas higher mean arterial pressure and central pulse pressure were associated with incident left ventricular hypertrophy (odds ratio per SD 1.37 and 1.45, respectively; P<0.01). On follow‐up, 297 of 5803 participants experienced a first CVD event. Presence of TOD was associated with a 33% greater hazard of incident CVD (95% CI, 0–77%; P<0.05), which was attenuated upon adjustment for baseline arterial stiffness measures by 5–21%. Conclusions Elevated arterial stiffness is associated with presence of TOD and may partially mediate the relations of TOD with incident CVD. Our observations in a large community‐based sample suggest that mitigating arterial stiffness may lower the burden of TOD and, in turn, clinical CVD.
The Notch pathway: a novel therapeutic target for cardiovascular diseases?

ABSTRACT Introduction: The Notch pathway is involved in determining cell fate during development and postnatally in continuously renewing tissues, such as the endothelium, the epithelium, and in the stem cells pool. The dysregulation of the Notch pathway is one of the causes of limited response, or resistance, to available cancer treatments and novel therapeutic strategies based on Notch inhibition are being investigated in preclinical and clinical studies in oncology. A large body of evidence now shows that the dysregulation of the Notch pathway is also involved in the pathophysiology of cardiovascular diseases (CVDs). Areas covered: This review discusses the molecular mechanisms involving Notch which underlie heart failure, aortic valve calcification, and aortic aneurysm. Expert opinion: Despite the existence of preventive, pharmacological and surgical interventions approaches, CVDs are the first causes of mortality worldwide. The Notch pathway is becoming increasingly recognized as being involved in heart failure, aortic aneurysm and aortic valve calcification, which are among the most common global causes of mortality due to CVDs. As already shown in cancer, the dissection of the biological processes and molecular mechanisms involving Notch should pave the way for new strategies to prevent and cure these diseases.
Wireless Experimental PID Temperature Control with Different Tuning Methods

In this study wireless experimental input/output data obtained from The Cussons P3005 type process control simulator. The Proportional-Integral-Derivative(PID) algorithm which is written in MATLAB is utilized to wireless temperature control and experiments achieved by using MATLAB/Simulink program. Ziegler-Nichols and Cohen-Coon tuning parameters which are determined with dynamic analyses are applied to the PID algoritm and the experimental control results compared by observing the temperature profiles. The wireless temperature control was applied to the system successfully and the efficiency of the this two tuning methods was observed by calculating the Integral Square of the Error (ISE) and the Integral Absolute value of the Error (IAE) from experimental results. The lower values of ISE and IAE, Cohen-Coon tuning method was discovered to be better than Ziegler-Nichols tuning method for this process. Wireless control tecnique can be proposed for industrial heating-cooling systems.
A network meta-analysis protocol of adjuvant chemotherapy for unresectable patients with advanced gastric cancer

Abstract Background: The treatment methods about surgery, chemotherapy, and radiation therapy were recommended for gastric cancer (GC) patients by National Comprehensive Cancer Network (NCCN) guidelines. However, for the advanced gastric cancer patients or with metastatic lesions who have lost their chance of surgery, the current adjuvant chemotherapy treatments are still controversial. Therefore, this network meta-analysis is mainly to assess the relative efficacy of different adjuvant chemotherapy regimens for advanced gastric cancer (AGC). Methods: In order to compare the relative efficacy among different adjuvant chemotherapy regimens for AGC patients, randomized controlled trials (RCTs) and non-RCTs were systematic searched in PubMed, Web of Science, Clinical Trials, Cochrane Library and Embase database. R-3.4. 1 software will be used for data analysis. The risk of bias in RCTs and non-RCTs will be evaluated through the risk of bias tool from the Cochrane Handbook version 5.1. 0 and non-randomized studies of interventions (ROBINS-I), respectively. Results and conclusion: The results of this network meta-analysis will evaluate the relative effectiveness and rank the interventions among all chemotherapy methods for unresectable AGC patients, and provide more evidence-based guidance in clinical practice. Protocol registration number: CRD42018111835.