Miracle-dz/UniFAR-FTUs huggingface dataset:
UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM FARMÁCIA DESENVOLVIMENTO DE SISTEMAS MICROESTRUTURADOS A BASE DE POLIHIDROXIALCANOATOS PARA A LIBERAÇÃO PERIODONTAL DO NAPROXENO

Title: Development of microstructured systems based on polyhydroxyalkanoates for periodontal release of naproxen The polyhydroxyalkanoates (PHAs) are polymers widely used in the pharmaceutical industry for its characteristics of biodegradability and biocompatibility. Poly(3-hydroxybutyrate) (P(3HB)) and its copolymer Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (P(3HB-co3HV)) are the most common of this group and have been extensively studied as drug carriers. In this way, PHAs are interesting materials for applications in both health and pharmaceutical industries as a constituent of controlled release dosage forms. As strategy to control the release, different materials can be used in a formulation which can modify and improve its physicochemical properties. In this context, Naproxen (NPX) was encapsulated in microstructured systems obtained from polyhydroxyalkanoates, cellulose acetate and their blends, in order to evaluate the physical and chemical properties of the microspheres and to obtain a prolonged-release system for the treatment of periodontitis. These microspheres were then dispersed in poloxamer gel in order to keep the particles of the periodontal pocket. In order to observe the effect on size and encapsulation efficiency, the molecular weight of P(3HB) was reduced by synthesis with sodium borohydride. The method of emulsion/solvent evaporation was used to prepare the microspheres of PHA and ethylcellulose in proportions of 100:0, 50:50 and 0:100 (w/w), using chloroform and acetone as solvent. The values of encapsulation efficiency and drug content ranged from 33.21 to 99.11% and 3.14 to 9.91 mg NPX/100 mg formulation, respectively. Spherical particles were obtained with average diameter between 6.145 and 16.266 micrometers. The reduction of the molecular weight of P(3HB) and addition of ethyl cellulose caused a reduction in average particle diameter. Analyses by differential scanning calorimetry and Xray diffraction indicated an interaction between the components of the formulation. Studies of release in simulated saliva showed that the concentration of cellulose acetate on microspheres resulted in a pronounced release of naproxen. Moreover, mathematical models demonstrated that the mechanism of drug release is predominantly controlled by diffusion.
Influencia de las Tecnologías de Información en los procesos contables de las organizaciones

En la presente investigación se pretende determinar la in uencia de las TIC en los procesos contables de las organizaciones, los mismos que son considerados como herramientas, informáticas que procesan, sintetizan, almacenan y difunden información digitalizada, debido a que su uso facilita la gestión ya que permite comunicarse de la manera más efectiva con sus clientes y ofrecer servicios de forma más rápida, lo cual conlleva una mejora en la calidad del servicio prestado y en la satisfacción del cliente. El manejo masivo de información y el avance de la tecnología, han provocado una necesidad en el uso de todas las áreas funcionales de la empresa, debido a la complejidad y el volumen de operaciones que puede tener una empresa pública o privada, es necesario tener un control de sus activos, pasivos y patrimonio y poder evaluar cómo ha sido la gestión administrativa y nanciera de un determinado ejercicio scal. El objetivo de esta investigación es analizar su enfoque dentro de las organizaciones. Se aplicará el método histórico lógico y sistémico que permitirá́ concluir que es necesario optimizar los procesos administrativos, nancieros y de cumplimiento para una adecuada toma de decisiones del nivel directivo.
Studies in semiconducting metal oxides in conjunction with silicon for solid state gas sensors. Progress report for April 1, 1977--March 31, 1978

ZnO films have been reproducibly grown using chemical deposition and radio-frequency sputtering techniques. These films are polycrystalline or amorphous, but are stable, uniform and lend themselves to material characterization by Auger and x-ray analysis techniques, and electrical measurements. SnO/sub 2/ films have been reproducibly grown by chemical vapor deposition, vacuum deposition and radio-frequency sputtering techniques. These films are also polycrystalline or amorphous, and lend themselves to material characterization and measurements. By vacuum deposition techniques, Si-SnO/sub 2/ heterojunctions have been grown, which exhibit good rectification properties. An original thermodynamic analysis of the growth of SnO/sub 2/ by a chemical vapor deposition technique based on the reaction between SnCl/sub 4/ and H/sub 2/O has been developed and submitted for publication. Pd-SiO/sub 2/-Si Schottky barrier diodes exhibiting excellent rectification properties have been successfully fabricated. A formalism has been established for the analysis of the behavior of these devices in the presence of H/sub 2/, H/sub 2/S and CO. The ZnO films grown by chemical deposition have proven to be sensitive to CO and CH/sub 4/. Sputtered ZnO films are sensitive to O/sub 2/ and H/sub 2/. SnO/sub 2/ films grown by chemical vapor deposition are not very sensitive to gases. Sputtered films, however,more » are very sensitive to H/sub 2/ and H/sub 2/S. The Pd-SiO/sub 2/-Si diodes are extremely sensitive to H/sub 2/, H/sub 2/S and NH/sub 3/, and, under certain conditions, to CO. A microprocessor data processing system has been developed incorporating gas sensors in the presence of a variety of gases and gas mixtures. « less
AFRICAN ECONOMIC PARADOX: INDUSTRIALIZATION CREATING JOBS AND ADDED VALUE OR ACTIVE PARTICIPATION IN GLOBAL VALUE CHAINS: WHAT SOLUTIONS TO DEVELOP FOR THE LESS ADVANCED AND LANDLOCKED COUNTRIES LIKE BURKINA FASO?

The United Nations Economic Commission for Africa (2016) calls for resources for the implementation of the Action Plan for Accelerated Industrial Development in Africa, and states that: “Industrialization is essential for African countries as a means of increasing income, creating jobs, developing value-added activities and diversifying economies”. The United Nations Development Program (UNDP), the African Development Bank (AFDB), and the Organization for Cooperation and Economics Development (OCED, 2014, p. 16) explain the benefits to African countries’ participation in Global Value Chains (GVC) to industrialize without having to implement all stages of the chain. They add that the acquisition of new production capacities can allow countries and companies to move upmarket, which is to say to increase their share of value added in a GVC. But the opposite is the case, at least in some countries like Burkina Faso. We are witnessing a “specialization of primary products (cotton and non-monetary gold), to the detriment of manufacturing industry with high potential for multiplier effects on local economies” National Plan for Economic and Social Development of Burkina Faso (PNDES, 2017, p.12). Cusolito and al. (2016) mention that overcoming a series of obstacles (such as bad policies and governance, insufficient technology and skills) is the way to actively participate in GVCs. Yet OPEN it is these same obstacles that have always prevented the industrialization of Sub-Saharan Africa (excluding South Africa). The results show that the Global Value Chains (GVC) contribute to the creation of added value in developing countries what has an effect on industrialization
Impact of Vermicompost Fertilizer on Spinach Yield and Nutritional Components

Alternative fertilization practices, such the use of vermicompost (VC), have shown great potential to improve both the physical and biological attributes of soils and supplement the nutrient status of soils to improve fertility for vegetable crop production. Modification of soils with coffee vermicompost (CVC) has the potential to improve soil organic content, structure, and microbial activity. Generally, organic fertilizers with slow release nutrient capabilities efficiently use nitrogen and reduce nitrate levels in leafy green vegetables and have been shown to increase ascorbic acid (AA) content. A greenhouse study was conducted over two growing seasons (2011 and 2012) to assess the influence of four CVC rates (0, 25%, 50%, and 75% v/v of soil mix) on Spinacia oleracea growth parameters including fresh leaf weight, leaf area, plant height, leaf number, fresh leaf ascorbic acid (AA) and dry leaf nitrate (DLN). Spinach leaf number and fresh leaf weight increased with CVC rate for both growing seasons and were best described by increasing linear relationships. Surprisingly, spinach AA content remained the same whether DLN content was high or low; and AA and nitrate content were both at highest levels with the 75% v/v CVC treatment in both years. These results indicated that applications of an alternative fertilizer such as CVC can improve spinach yield and that AA content does not always decrease with higher VC application rates, even as nitrate content increases.
Relationships of Family food environment with food and nutrition literacy in Chinese school-age children

Background: Eating behavior is inﬂuenced by multiple factors and understanding the interplay of these factors is necessary to promote children’s healthy food choice. This study investigated the relations of family food environment (FFE) with food and nutrition literacy (FNL) in Chinese school-age children.Methods: A total of 605 children aged 7-13 years from Grade 1 to 5, and their caregivers participated in the cross-sectional study in Beijing of China during April 2019. The FFE was assessed by the validated Family Food Environment Questionnaire for Chinese School-age Children (FFEQ-SC). For the children of Grade 3 to 5 (n=260), the FNL, including cognitive and skill domains, was assessed by Food and Nutrition Literacy Questionnaire for Chinese School-age Children (FNLQ-SC). Both FFEQ-SC and FNLQ-SC were developed firstly for Chinese school-age children who had good reliability. The anthropometric data (height and weight) was derived from local health information management system for primary schools.Results: Overall, 68.9% of the children’s families had high level of FFE. The total FNL score of 260 children at Grade 3-5 was 63.2±10.3. Comparison of children’s FNL scores among different levels of FFE showed the children with higher level of FFE, especially higher level of caregiver’s educational degree and FNL, were more likely to have higher FNL scores (P<0.05). The multivariate analysis showed the children’s total FNL score was significantly related with family caregiver (β= -0.123, P=0.04) and caregiver’s nutritional literacy (β= 0.210, P=0.002). Furthermore, the children with higher level of caregiver’s nutritional knowledge were less likely to be overweighted or obesese (OR=0.043, P=0.04). Conclusions: Family food environment, especially caregivers’ FNL, was related with children’s FNL, even the risk of overweight. These findings highlight the importance of targeting nutritional knowledge of family caregivers to facilitate the children’s FNL to maintain good health.
Hot spot identification by means of classification methods employing wavelet transform-based features

Background: Proteins can interact with one another by an interface composed of two proteins. Some of the interface residues - called hot spots - have the greatest impact on binding energy in a protein complex. This paper introduces the application of continuous wavelet transform based on the fast Fourier transform (CWTFT) to the analysis of hot spots in proteins.Results: The algorithm was evaluated by using data sets containing 30 proteins. From the number of tested classifiers the best 10 models were preferred. The classifiers achieved sensitivity of 52% - 71%, specificity of 70% - 83% and accuracy of 70% - 74%. Conclusion: The analyses show that the method combining CWTFT and classification algorithms is able to identify hot spot residues with valuable results.Methods: The basis of the algorithm is extraction of features from spectra obtained by using CWTFT with different wavelet functions including Morlet, m^th order derivative of Gaussian, Paul and Bump wavelets. Then, the classifiers that are able to separate hot spot from non-hot spot residues according to these features are applied.
The Allostery Landscape: Quantifying Thermodynamic Couplings in Biomolecular Systems

Allostery plays a fundamental role in most biological processes. However, little theory is available to describe it outside of two-state models. Here we use a statistical mechanical approach to show that the allosteric coupling between two collective variables is not a single number, but instead a two-dimensional thermodynamic coupling function that is directly related to the mutual information from information theory and the copula density function from probability theory. On this basis, we demonstrate how to quantify the contribution of specific energy terms to this thermodynamic coupling function, enabling an approximate decomposition that reveals the mechanism of allostery. We illustrate the thermodynamic coupling function and its use by showing how allosteric coupling in the alanine dipeptide molecule contributes to the overall shape of the Φ/Ψ free energy surface, and by identifying the interactions that are necessary for this coupling.
Effects of Particle Size, Stem Component and Genotype on Absorbency of Kenaf (Hibiscus Cannabinus L.) Grown in Nigeria for Oil-Spill Clean-Up

The efficacies of different products made from different parts of the stem of different varieties of kenaf grown in Nigeria as oil absorbents were tested. Particle sizes, genotypes and whether mixed or sole stem core or bast differed among the treatments. The fibre component sank in water, and so was not buoyant; the core was partially buoyant while the mixed fibre and core was completely buoyant. Sorption capacity was the highest in the ground whole stem (8.16 g oil/g sorbent), which also retained (6.31 g oil/g sorbent) the highest quantity of oil. Sorption and retention of oil were the lowest in the fibre (1.66 and 0.69 g oil/g sorbent, respectively). After the first use, only the ground stem can be used to re-absorb up to 1.97 g oil/g sorbent of used sorbent. A mixture of genotypes was more absorbent than a single genotype. The implications of these findings in absorbency research are discussed.
Changes in polymeric substances during acidification of bamboo (Bambusa procera) black liquors

The structural changes in the dissolved material (lignin and carbohydrates) of bamboo (Bambusa procera) soda and kraft black liquors, occurring during acidification (pH from 12-13 to 7 and 2), were studied. The characteristic differences between soda and kraft liquors in terms of average molecular masses (M w and M n ), polydispersity (M w /M n ), and molecular mass distribution (MMD) were detected. The results obtained revealed that high-molecular-mass lignin fragments were mainly precipitated in the 7-11 pH range, and at pH 11, a significant proportion (about 85% of organics) of carbohydrates being also present in these precipitates. The relative composition of monosaccharide moieties in the carbohydrates of the precipitates changed only slightly during acidification, the most prominent units being glucose (50-65% of monosaccharides) and xylose (35-45% of monosaccharides).
Education Necessary for Air Force Software Managers to Use the Ada Programming Language and Software Engineering Effectively

Abstract : This research investigated the perceived Ada and software engineering education needs of software managers throughout the Air Force and provided recommendations to Air Staff for developing the education. Since the Department of Defense mandated all DOD agencies use the Ada programming language for software development, the education of the personnel who have to support the policy has lagged behind the implementation Ada is not a simple language to use and is only fully effective if used with sound software engineering principles. A survey was given to Air Force mid-level personnel who manage software in some capacity. Of the software personnel surveyed, 48 percent indicated that Ada education would help. Less than 45 percent of the personnel who work with Ada have had a formal course in using the language while over 70 percent of the people have had some form of formal software engineering education. This research also investigated the required frequency of education. The respondents indicated that the frequency (periodic or as-needed) should depend on the nature of the individuals job and rank or position.
Estimate Private Rate of Return on Technical Vocation School and Formal School: Evidence from Kuwait

In this paper we asked what can account for the continuing provide technical vocational education in Kuwait? Where the level of development is high and there are high wages government jobs. On the other hand the researcher try to find which of education system track, formal or technical vocation education system is more profitable for individuals in Kuwait. We argue that the answers to these questions are connected through the nature of the earning function and the importance of age effects. This paper will be complemented by an important gap in the development of tools and techniques for analysis part of the education system in the State of Kuwait. This paper is important from three standpoints. First, in order to estimate the effect of education track/path on earnings, the most recent and nationally representative data is used which provides detailed information on the variables. Second, it is an effort to provide an evidence for the comparison between Vocational track/path and Formal track/path in Kuwait education system based on individual earnings. Third, this study provides the policy makers with a helpful technique to monitoring the expenditure on education. To provide policy makers and top management with information needed for comparing technical vocation education with formal education system in Kuwait, this paper offer a new evidence on continue providing technical vocation education in Kuwait by using 2010 Kuwait Civil Service Commission employees database; moreover it is an effort of estimating the private rate of return on formal and technical vocation education system by applying the earning equation. The results suggested keep on offering the technical vocation schools also; find a significant effect on wages depend on the type of education track system. Moreover, the technical vocation education slightly higher returns than the formal education. Original Article PII: S232247701800003-8 Rec. 14 April, 2020 Acc. 14 May, 2020 Pub. 25 June, 2020
Murciélagos (Chiroptera) del departamento del Tolima, Colombia: diversidad en un bosque húmedo tropical y actualizacion de la lista de especies del departamento

Los murciélagos (Chiroptera) representan el orden de mamíferos con mayor número de especies en Colombia, sin embargo, aún son escasos los estudios sobre la diversidad de este grupo taxonómico en algunas regiones del país. Objetivo. Describir la diversidad taxonómica de murciélagos en un bosque húmedo tropical (Reserva Agroecológica Santa Librada: RASL) en el departamento del Tolima, Colombia, y actualizar la lista de especies de los murciélagos en el departamento. Metodología. Se realizaron muestreos sistemáticos utilizando cinco redes de niebla y capturas manuales entre el 2016 y 2018 en la RASL, así como una revisión exhaustiva de registros sobre murciélagos del Tolima, a partir de fuentes literarias y especímenes en museos. Resultados. Para la RASL se registraron 19 especies pertenecientes a 13 géneros y 4 familias. Phyllostomidae fue la familia más representativa con 191 registros. Para el departamento se confirma la presencia de 99 especies de murciélagos. Conclusiones. La diversidad de murciélagos en el departamento del Tolima es mayor de lo que se ha considerado. Se adicionan 18 registros a la lista departamental y se identifican algunos vacíos de información y errores que pueden ser fuente de malas interpretaciones sobre la diversidad de murciélagos del Tolima reportada en la literatura. Finalmente, se reconoce la importancia de los parches de bosque húmedo tropical al norte del Tolima como sitios que albergan una alta diversidad de murciélagos, en su mayoría inexplorada.
Zero Trust Validation: From Practical Approaches to Theory

How can high-level directives concerning risk, cybersecurity and compliance be operationalized in the central nervous system of any organization above a certain complexity? How can the effectiveness of technological solutions for security be proven and measured, and how can this technology be aligned with the governance and financial goals at the board level? These are the essential questions for any CEO, CIO or CISO that is concerned with the wellbeing of the firm. The concept of Zero Trust (ZT) approaches information and cybersecurity from the perspective of the asset to be protected, and from the value that asset represents. Zero Trust has been around for quite some time. Most professionals associate Zero Trust with a particular architectural approach to cybersecurity, involving concepts such as segments, resources that are accessed in a secure manner and the maxim “always verify never trust”. This paper describes the current state of the art in Zero Trust usage. We investigate the limitations of current approaches and how these are addressed in the form of Critical Success Factors in the Zero Trust Framework developed by ON2IT ‘Zero Trust Innovators’ (1). Furthermore, this paper describes the design and engineering of a Zero Trust artifact that addresses the problems at hand (2), according to Design Science Research (DSR). The last part of this paper outlines the setup of an empirical validation trough practitioner oriented research, in order to gain a broader acceptance and implementation of Zero Trust strategies (3). The final result is a proposed framework and associated technology which, via Zero Trust principles, addresses multiple layers of the organization to grasp and align cybersecurity risks and understand the readiness and fitness of the organization and its measures to counter cybersecurity risks.
Mechanisms for Stable Solid Electrolyte Interphase Formation and Improved Cycling Stability of Tin‐Based Battery Anode in Fluoroethylene Carbonate‐Containing Electrolyte

Tin‐based anode materials are promising candidates for high‐energy density Li‐ion batteries. Unstable anode–electrolyte interface is a critical problem that needs to be resolved for these materials. The improvement of solid electrolyte interphase (SEI) stability and cycling stability of fluorine‐doped Sn–Ni film electrode is observed by the use of fluoroethylene carbonate (FEC)‐based electrolyte with respect to ethylene carbonate (EC)‐based conventional electrolyte. Mechanisms of FEC‐derived SEI formation and stabilization are investigated using state of charge‐dependent ex situ attenuated total reflection FTIR combined with X‐ray photoelectron spectroscopy. The data reveal that enriched fluorinated compounds of SnF4, SnF2, and LiF form in FEC‐based electrolyte as the earliest SEI compounds, and those inorganic species together with Li2CO3 and organic/polymeric compounds effectively passivate the electrode surface at a limited SEI thickness and inhibit further electrolyte decomposition, in contrast to continuous electrolyte decomposition with cycling in EC‐based electrolyte. The stable FEC‐derived SEI layer limits cracks but improves particles connectivity, leading to improved cycling stability of the battery. The SEI formation mechanism by FEC reduction at the surface of the electrode is proposed. The approach of SEI control for the performance improvement gives an insight into the importance of SEI composition and stability in achieving improved battery performance.