Miracle-dz/UniFAR-FTUs huggingface dataset:
Model-Based Specification of Control Architectures for Compliant Interaction with the Environment

In recent years the need for manipulation tasks in the industrial as well as in the service robotics domain that require compliant interaction with the environment rose. Since then, an increased number of publications use a model-driven approach to describe these tasks. High-level tasks and sequences of skills are coordinated to achieve a desired motion for e.g., screwing, polishing, or snap mounting [1], [2]. Even though the awareness of the environment, especially in terms of contact situations, is essential for successful task execution, it is too often neglected or considered insufficiently.In this paper, we present a model-based approach, using domain-specific languages (DSL), that enables the explicit modeling of the environment in terms of contact situations. Decoupling the environment model from the skills, fosters exchangeability and allows the adaptation to different environmental situations. This way, an explicit but non-invasive link is established to the skills, enabling the environment model to provide a context to constrain the execution of the skills. Further, we present a synthesis from the modeled contact situations to a real-time component-based control architecture, which executes the skills subject to the active environmental context. A dual arm yoga mat rolling task is used to show the impact of the environment model on the skill execution.
Catalysis of hydrosilylation: Part XXXI. Functionalization of poly(methylhydro)siloxanes via hydrosilylation of allyl derivatives†

The synthesis of functional poly(methylhydro)siloxanes has been successfully performed by effective quantitative hydrosilylation of allyl derivatives (allyl phenyl ether, allyl glycidyl ether, allyl methacrylate, allyl chloride, allylamine) and 1-octene with poly(methylhydro)siloxanes catalyzed by platinum [Pt(PPh3)2(CH2=CH2), PtCl2(PPh3)2, H2PtCl6–cyclohexanone] and ruthenium (Ru3(CO)12) complexes. The products were isolated and characterized by 1H NMR, FT IR and GPC methods and can be regarded as examples of well-defined functionalized polysiloxanes with various practical applications. © 1997 John Wiley & Sons, Ltd.
Recognition of Diabetes in a Multi-ethnic Population: Results from a Nationally Representative Population-Based Study

Background The prevalence of diabetes is on the rise in developed countries. Yet discrepancies exist in reports regarding the level of knowledge of diabetes. This study evaluates the recognition of diabetes among residents in the Singapore population. Sociodemographic characteristics associated with the ability to correctly recognise diabetes were also examined. Methods This was a nationwide cross-sectional vignette-based study. Data were collected from 2895 residents aged 18 years and above through face-to-face interviews, of which 436 are persons with diabetes. Descriptive statistics, chi-square tests, and binary logistic regression were used in the analyses. Results In total, 82.7% (2418/2895) of respondents recognised diabetes correctly. In adjusted models, correct recognition was significantly higher among respondents aged 35-49 years (OR, 1.85; 95% CI, 1.15 to 2.98; P= 0.01), 50-64 years (odds ratio [OR], 2.06; 95% confidence interval [CI], 1.19 to 3.56; P= 0.01), ethnic Malays (OR, 1.39; 95% CI, 1.02 to 1.89; P= 0.04) (vs. Chinese) and persons with diagnosed diabetes (OR, 2.64; 95% CI, 1.38 to 5.08; P < 0.01). Being male (OR, 0.64; 95% CI, 0.46 to 0.90; P < 0.01), ethnic Others (OR, 0.59; 95% CI, 0.37 to 0.93; P < 0.01), and being unemployed (OR, 0.48; 95% CI, 0.25 to 0.92; P= 0.03), were significantly associated with poor recognition of diabetes. Conclusion Overall public recognition of diabetes is high, but the significant gaps in knowledge in certain demographic groups are of concern. Public health interventions aimed at preventing and controlling diabetes should continue to target all members of the population with accurate and appropriate information. Ongoing efforts of diabetes awareness and educational programs need to be improved, particularly for young adults, males, and the unemployed.
Extremely high SARS-CoV-2 seroprevalence in a strictly-Orthodox Jewish community in the UK

Abstract Background Ethnic and religious minorities have been disproportionately affected by SARS-CoV-2 worldwide. The UK strictly-Orthodox Jewish community has been severely affected by the pandemic. This group shares characteristics with other ethnic minorities including larger family sizes, higher rates of household crowding and relative socioeconomic deprivation. We studied a UK strictly-Orthodox Jewish population to understand how COVID-19 had spread within this community. Methods We performed a household-focused cross-sectional SARS-CoV-2 serosurvey specific to three antigen targets. Randomly-selected households completed a standardised questionnaire and underwent serological testing with a multiplex assay for SARS-CoV-2 IgG antibodies. We report clinical illness and testing before the serosurvey, seroprevalence stratified by age and gender. We used random-effects models to identify factors associated with infection and antibody titres. Findings A total of 343 households, consisting of 1,759 individuals, were recruited. Serum was available for 1,242 participants. The overall seroprevalence for SARS-CoV-2 was 64.3% (95% CI 61.6-67.0%). The lowest seroprevalence was 27.6% in children under 5 years and rose to 73.8% in secondary school children and 74% in adults. Antibody titres were higher in symptomatic individuals and declined over time since reported COVID-19 symptoms, with the decline more marked for nucleocapsid titres. Interpretation In this tight-knit religious minority population in the UK, we report one of the highest SARS-CoV-2 seroprevalence levels in the world to date. In the context of this high force of infection, all age groups experienced a high burden of infection. Actions to reduce the burden of disease in this and other minority populations are urgently required.
Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes

As the threat of Covid-19 continues and in the face of vaccine dose shortages and logistical challenges, various deployment strategies are being proposed to increase population immunity levels. How timing of delivery of the second dose affects infection burden but also prospects for the evolution of viral immune escape are critical questions. Both hinge on the strength and duration (i.e. robustness) of the immune response elicited by a single dose, compared to natural and two-dose immunity. Building on an existing immuno-epidemiological model, we find that in the short-term, focusing on one dose generally decreases infections, but longer-term outcomes depend on this relative immune robustness. We then explore three scenarios of selection, evaluating how different second dose delays might drive immune escape via a build-up of partially immune individuals. Under certain scenarios, we find that a one-dose policy may increase the potential for antigenic evolution. We highlight the critical need to test viral loads and quantify immune responses after one vaccine dose, and to ramp up vaccination efforts throughout the world.
Sex Disparities and Neutralizing-Antibody Durability to SARS-CoV-2 Infection in Convalescent Individuals

In this study, we found that neutralizing antibody responses in COVID-19-convalescent individuals vary in magnitude but are durable and correlate well with receptor binding domain (RBD) Ig binding antibody levels compared to other SARS-CoV-2 antigen responses. In our cohort, higher neutralizing antibody titers are independently and significantly associated with male sex compared to female sex. ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has now caused over 2 million deaths worldwide and continues to expand. Currently, much is unknown about functionally neutralizing human antibody responses and durability to SARS-CoV-2 months after infection or the reason for the discrepancy in COVID-19 disease and sex. Using convalescent-phase sera collected from 101 COVID-19-recovered individuals 21 to 212 days after symptom onset with 48 additional longitudinal samples, we measured functionality and durability of serum antibodies. We also evaluated associations of individual demographic and clinical parameters with functional neutralizing antibody responses to COVID-19. We found robust antibody durability out to 6 months, as well as significant positive associations with the magnitude of the neutralizing antibody response and male sex and in individuals with cardiometabolic comorbidities. IMPORTANCE In this study, we found that neutralizing antibody responses in COVID-19-convalescent individuals vary in magnitude but are durable and correlate well with receptor binding domain (RBD) Ig binding antibody levels compared to other SARS-CoV-2 antigen responses. In our cohort, higher neutralizing antibody titers are independently and significantly associated with male sex compared to female sex. We also show for the first time that higher convalescent antibody titers in male donors are associated with increased age and symptom grade. Furthermore, cardiometabolic comorbidities are associated with higher antibody titers independently of sex. Here, we present an in-depth evaluation of serologic, demographic, and clinical correlates of functional antibody responses and durability to SARS-CoV-2 which supports the growing literature on sex discrepancies regarding COVID-19 disease morbidity and mortality, as well as functional neutralizing antibody responses to SARS-CoV-2.
S100A4 cooperates with HIF-1 to regulate migration and invasion of gastric can- cer cells via WNT/β-catenin pathway

[摘 要] 目的:探讨S100A4在低氧条件下对胃癌细胞SGC-7901迁移及侵袭的作用及其可能的机制。 方法:将化学合成的 siS100A4质粒和阴性对照(si-Ctrl)质粒分别转染胃癌细胞株 SGC-7901,根据培养条件的不同分为常氧条件(normal,Nor)+ siS100A4组、Nor + si-Ctrl组、低氧条件(hypoxia,Hyp)+ si-Ctrl)组、Hyp + si-S100A4组。 应用Western blotting检测低氧条件下胃癌 SGC-7901细胞中HIF-1及S100A4蛋白的表达变化,检测低氧条件下胃癌细胞中抑制S100A4的表达对细胞中S100A4、β-catenin 及TCF-4表达的影响;Transwell小室法分别检测低氧及S100A4对胃癌SGC-7901细胞迁移及侵袭能力的影响。 结果:低氧条件 下:(1)胃癌SGC-7901细胞中HIF-1和S100A4表达水平均明显升高(3.12±0.23 vs 1.02±0.05,P<0.01;2.75±0.32 vs 1.05±0.07,P< 0.01),且两者变化明显相关(r =0.67,P<0.01); (2) 胃癌SGC-7901细胞的侵袭及迁移能力增加[(223.31±35.12) vs (131.29±26.40)、 (142.27±26.37)个, P<0.05]。 干扰低氧条件中S100A4的表达:(1) 明显减少低氧对细胞中β-catenin及TCF-4的促进作用(均P< 0.01);(2) 明显减少低氧对SGC-7901细胞的侵袭及迁移能力的促进作用[(161.37±31.02) vs (88.21±22.42)、(95.36±21.29)个, P< 0.05]。 结论:S100A4能够促进胃癌细胞SGC-7901的迁移和侵袭,该作用可能是通过S100A4协同HIF-1通过Wnt/β-catenin通路 的调控实现的。 [关键词] 缺氧诱导因子-1; S100A4蛋白; Wnt/β-catenin通路; 胃癌;侵袭 [中图分类号] R737.1 [文献标识码] A [文章编号] 1007-385X(2017)09-0851-05
A Weight-Analysis Technique of Existing Research on E-Government Implementation Challenges in Developing Countries

The e-government application may enhance government facilities for its shareholders. Nevertheless, implementing such system faces many difficulties and obstacles. The considerable debacle of e-government inspires studies on those obstacles, especially in developing countries around the world. To examine the e-government implementation challenges more accurately, we have collected more than 50researchesreleasedafter 2010from various and multiple database sources such as IEEE Explore, Science Direct, Emerald, and Springer Link. For accomplishing our study, we have adhered to scientifically accepted top practices for researchers. According to the instructions, we have developed study objectives, in the mean time; we have used a method depending on certain criteria to achieve our study objectives. In the process of researching, we have demonstrated that there is lack of familiarity of the term e-government and there are obstacles associated with the application of an electronic system. There is a clear difference regarding the challenges hindering the implementation of an electronic government in underdeveloped nations, and these challenges differ from one country to another according to the location, culture, infrastructure, and organization conditions, in addition to social and political obstacles.the study found that the most important challenges facing the governments in implementing e-government are summarized in the organizational, political, social, and infrastructure challenges.this research aims to accomplish a thorough analysis of findings reported in the published studies regarding the challenges facing the implementation of e-government in developing countries.
Morphological identification of adult male Haemonchus species in goats from Thailand and Lao PDR.

Haemonchus spp. or barber's pole worms are one of the most highly pathogenic nematodes of ruminants causing economic losses in livestock worldwide. The current study was a first attempt to identify Haemonchus spp. from goats in Thailand and Lao PDR. Utilizing the inexpensive tools of the discriminant function (DF) combined with synlophe patterns is fundamental for understanding their epidemiological aspects. In total, 255 randomly chosen adult male Haemonchus worms from goats in various areas in each country were identified individually. For both these countries, about 94% based on the DF values, and 99%, 98%, and 97% based on synlophe patterns in the region of the esophageal intestinal junction (EI), 4 mm from the anterior end, and at both these positions, respectively, were identified as H. contortus. Other identified specimens defined as H. placei and hybrids as well as unclassified species based on synlophe patterns were proved using polymerase chain reaction (PCR); this also included some randomly chosen H. contortus by DF and synlophe patterns. All those specimens were confirmed as H. contortus being strongly supported by some genetic evidences and UPGMA analysis. Thus, it was assumed that all specimens in the current study were H. contortus. The morphological differences of this predominant species (H. contortus) in goats between the two countries were: body length, gubernaculum length, and left spicule barb length, while almost all characters of male worms individually measured appeared to overlap, mostly in H. contortus and H. placei, which may lead to misclassification. Therefore, using the DF along with synlophe patterns can assist in increasing the accuracy of Haemonchus spp. identification from goats in some areas where funding is limited, particularly in Lao PDR. The present results revealed that synlophe patterns in the EI region seemed to be promising for the identification of Haemonchus spp. , while molecular techniques are also required to address ambiguous identification with some specimens.
Sentimental Analysis of Product Reviews for e-Commerce Websites

----------------------------------------------------------------------***---------------------------------------------------------------------- Abstract — In today’s world people tend to buy product online rather than purchasing manually. There are many e-shopping websites to purchase the product. People look through many e-Commerce websites about the product review before buying the product. It is a tedious task for the consumer to look through all the reviews in all the websites. The review may be present as positive, negative or neutral. It is possible to analyze huge reviews by using sentiment analysis. Sentimental Analysis is a machine learning technique to analyze the review as positive, negative or neutral. By using Sentimental Analysis, the sentiment of the single product can be compared between many e-Commerce websites. The aim of this paper is to suggest the user in which website the product can be bought based on positive reviews.
OI moves in SMEs . Pathways to success

The paper is building on the 'OI move' concept developed to disentangle the OI journey. OI moves represent identifiable OI activities in a SME and two of the most important aspects of an ‘OI move’ are knowledge inflows (who is the SME innovating with? ) and knowledge outflows (who is exploiting the result? ). Knowledge inflows can be carried out with a variety of partners while knowledge outflows can be delivered through various exploitation models. Combining all these options forms a typology of 24 types of OI moves discussed in another paper (Livieratos et al., 2020). However, not much is known about the sequence of OI moves that form ‘pathways’ leading to successful innovation and business outcomes. To this end, the aim of the study is to define patterns of successful OI pathways for SMEs. The study is based on a dataset of 500 OI moves extracted from 106 case studies of European innovative SMEs. The sequence of the OI moves in each SME, and the success score of each OI move were analyzed using machine learning techniques (association analysis), resulting to 32 rules of successful OI pathways of SME presented in the form of a directed graph. Main findings up to this point indicate that four OI moves play a major role in forming successful OI journeys: collaboration with R&D service providers, with complementary partners and with customers and users, all of them associate with internal exploitation. These four OI moves have a mutually reinforcing effect, with a virtuous cycle leading to more success over time. The identified This paper was presented at The ISPIM Innovation Conference – Innovating Our Common Future, Berlin, Germany on 7-10 June 2020. Event Proceedings: LUT Scientific and Expertise Publications: ISBN 978-952-335-467-8 2 successful OI pathways provide practitioners with a 'recommended rule of thumb' when selecting the next OI moves based on OI journeys that have worked well for other SMEs.
Chemical composition and sensory evaluation of potato-sprouted Africa yam beans based complementary food fortified with palm weevil

This work evaluated nutritional components of complementary food obtained from mixes of sweet potato (SP), African yam bean (AYB) and palm weevil (PW). SP and AYB were pressure-cooked using autoclave at 121o C for 10 and 60 minutes, respectively. Four blends coded Control (100% Sweet potato) CF1 (80% sweet potato: 15% Africa yam bean: 5% palm weevil). CF2 (70% Sweet potato: 20% Africa yam bean: 10% palm weevil) and CF3 (60% sweet potato: 25% Africa yam bean: 15% palm weevil). The blends were analyzed for proximate compositions and functional and sensory attributes. Significant (p
Genotoxicity and effects of nanosilver contamination in drinking water disinfection

This study was conducted to examine the genotoxicity and the influence of silver nanoparticles (AgNPs) contamination when drinking water is exposed to five different disinfection treatments: chlorine, chlorine dioxide, ozone, ozone/chlorine and ozone/chlorine dioxide. Experiments were conducted with water samples of different chemical composition, from three water supply systems in Croatia. AgNPs are of interest because of their use as an antimicrobial in numerous commercial products, and as a drinking water disinfection agent. To examine possible effects of AgNP contamination, the disinfection treatments were repeated with AgNPs in the water samples. AgNP contamination generally caused a decrease in the level of trihalomethanes by up to 59%. Influence of AgNPs on bromide ion incorporation into disinfection by-products (DBPs) was also examined. The most obvious example was the Osi water where ozonation step prior to chlorination increased the bromine incorporation factor from 0.156 to 0.339, while addition of AgNPs limited the increase to 0.249. Also, AgNP presence in almost all disinfection treatments increased dicarbonyl disinfection by-products. All treated waters were tested for genotoxicity using the comet assay and showed similar genotoxic potential. The results are preliminary, but could provide a basis for further studies evaluating the environmental impact of AgNPs in natural aquatic systems.
Ethylene/1‐hexene copolymerization with Ph2C(Cp)(Flu)ZrCl2 derivatives: correlation between ligand structure and copolymerization behavior at high temperature

Ethylene homo- and copolymerization with 1-hexene were performed in the presence of diphenylmethylidene(cyclopentadienyl)(fluorenyl)zirconium dichloride (Ph 2 C(Cp)(Flu)ZrCl 2 ) derivatives activated with dimethylanilinium tetrakis(pentafluorophenyl)borate (Me 2 PhNH.(C 6 F 5 )4)/triisobutylaluminium (i-Bu 3 Al) or methylaluminoxane (MAO) to study the role of the substituent on activity, comonomer incorporation and molecular weight. C 1 symmetric metallocenes which have several substituents in β-position of the cyclopentadienyl ligand produce lower molecular weight copolymers than the Ph 2 C(Cp)(Flu)ZrCl 2 catalyst at 200 °C, whereas the copolymerization reactivity is significantly influenced by the volume of the substituent: the trimethylsilyl substituted derivative produces ethylene/1-hexene copolymers with a broad chemical composition distribution. Polyethylene obtained with the diphenylmethylidene(cyclopentadienyl)(indenyl)zirconium dichloride (Ph 2 C(Cp)(Ind)ZrCl 2 ) based catalyst is branched, and the molecular weight distribution and the chemical composition distribution are significantly affected by the cocatalyst. C s symmetric metallocenes which have alkyl substituents in 2,7 position of the fluorenyl ligand produce higher molecular weight copolymers than the Ph 2 C(Cp)(Flu)ZrCl 2 catalyst with equal copolymerization reactivity.
The effects of Watsu therapy on autonomic cardiovascular modulation and flexibility of children with cerebral palsy

Background: We aimed to compare and examine the effect of aquatic interventions, Watsu® vs Immersion, on the autonomic nervous system and the range of motion in children with cerebral palsy, due to common belief that use of Watsu is beneficial for the special needs. Material and methods: Twenty-three children (age 7.5±2.8) were randomized to receive Watsu® therapy and Immersion interventions in the cross-over, age-stratified study. Each therapy session lasted 30 minutes twice a week for a total of 10 weeks in two non-consecutive periods. Short-term heart rate variability parameters by using a Polar H7 heart rate sensor with a signal processing software and the passive range of motion by using a universal goniometer was measured at baseline and post-treatment. Results: Watsu® therapy significantly improved the heart rate variability parameter (pNN50, t = 2.312, p = 0.031) and lower flexibility (t = 6.012, p = 0.000) in comparison to immersion. Conclusions: In comparison to immersion, Watsu® therapy was shown to be safe and effective for the autonomic modulation and flexibility of children with cerebral palsy. Therefore, it is recommended as a complementary tool for physical therapy on land.
Simulation of Transient Flow in Gas Pipelines Using the Finite Volume Method

gas pipelines, transient flow, compressible flow, isothermal flow, finite volume method The transient flow analysis is fundamental to the simulation of natural gas process, in order to adjust the system to real operative conditions and to obtain the highest level of efficiency, compliance and reliability. The simulation of natural gas pipelines and networks requires mathematical models that describe flow properties. Some models that have been developed year after year based on the laws of fluid mechanics that govern this process, interpreted as a system of equations difficult to solve. This investigation describes the fully implicit finite volume method for natural gas pipeline flow calculation under isothermal conditions and transient regime. The simplification, discretization scheme and implementation equations are approached throughout this paper. The model was subjected to two evaluations: sinusoidal variation of the mass flow and opening-closing valve at the outlet of the pipeline, it is compared with two models: fully implicit finite difference method and method of characteristics. This method proved to be efficient in the simulations of slow and fast transients, coinciding the flow oscillations with the natural frequency of natural gas pipeline.