Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigation of Brain Vascular Territories in Stroke Patients Detected Non-Valvular Atrial Fibrillation as an Etiological Factor

Bu calismada; non-valvuler atriyal fibrilasyon (NVAF) etyolojisine sahip inme hastalarinda serebral vaskuler bolgeleri arastirmak amaclandi. Ocak 2015-Eylul 2016 tarihleri arasinda hastanemize basvuran ve 55 yasin uzerinde olan, tibbi oykulerinde standart EKG veya Holter EKG kaydi bulunan veya NVAF tanisi konan ve iskemik serebrovaskuler hastalik teshisi alan 208 hasta calismaya dahil edildi. Calismamiz retrospektif verilerin bir analizi olarak tasarlanmistir. Hastalarin ayrintili oyku, fizik muayene ve elektrokardiyografi (EKG) degerlendirmeleri yapildi. Bulgularin tespitinde tanimlayici istatistikler kullanilmis ve t-testi, Pearson ki-kare ve Fisher'in kesin testi, farkliliklar analizi icin kullanilmistir. Hastalarin %53.8'i (n=112) erkek, %46.2'si (n=96) kadindi. Yas ortalamasi 73.5 idi. Orta serebral arter (MCA), NVAF'ye bagli inmelerde en sik vaskuler tutulum alaniydi. Superior serebellar arter (SCA) ve posterior serebral arter (PCA), MCA'yi takip etti. NVAF ile iliskili inmelerin yaklasik %64'u on sirkulasyon enfarktusu (ACI) ve %22'si arka sirkulasyon enfarktusu (PCI) idi. Yas ve gecmis inme oykusu faktorlerinde ACI lehine anlamli bir fark vardi (p 0.05). Sonuc olarak, akut olarak ortaya cikan enfarktlarda iskemiye ugrayan damar alaninin ve bu damar alani icin etiyolojik faktorun tahmin edilebilecegi vurgulanmistir.
Geburt des ersten Babys in der Schweiz nach Autotransplantation von kryokonserviertem Ovargewebe

Grosse Fortschritte bei der Therapie von malignen Tumoren haben in den letzten Jahren die Überlebensrate von jungen Patientinnen massiv verbessert. Leider haben viele Chemound Radiotherapien ein hohes Risiko für eine nachfolgende Infertilität. Eine vorzeitige Ovarialinsuffizienz ist eine bekannte Folge der Therapie mit Zytostatika. Die histologische Untersuchung von Ovarien nach Chemotherapie zeigt Veränderungen von einer erniedrigten Anzahl von Follikeln bis zu deren vollständigem Fehlen oder einer Ovarfibrose [1]. Der Zytostatika-Typ, die Dosis sowie die Therapiedauer bestimmen die Wahrscheinlichkeit für eine vorzeitige Ovarialinsuffizienz. Alkylierende Substanzen wie Cyclophosphamid und Ifosfamid schädigen das Gonadengewebe permanent durch eine chemische Interaktion mit der DNA. Eine grosse retrospektive Studie über Schwangerschaftsraten nach hämatopoetischer Stammzelltransplantation mit 37 362 Patientinnen zeigte, dass nur 0,6% der Frauen nach autologer oder allogener Stammzelltransplantation schwanger wurden [2]. Mit den steigenden Überlebensraten bei jungen Krebspatientinnen wächst das Bedürfnis nach fertilitätserhaltenden Massnahmen vor Therapiebeginn. Optionen sind die Kryokonservierung von Embryonen, Oozyten oder Ovargewebe. Donnez et al. berichteten 2004 über die erste Geburt nach Autotransplantation von kryokonserviertem Ovargewebe beim Menschen [3]. Inzwischen werden in der Literatur knapp 20 Fälle von gesunden Babys beschrieben, die nach Autotransplantation von kryokonserviertem Ovargewebe zu Welt kamen. Wir berichten über das erste Kind in der Schweiz.
Effect of restricted blood flow on muscle hypotrophy & O2 saturation level on weight training

The main purpose of the study was to find out the effect of the restricted blood flow on muscle hypotrophy and O2 saturation level. Ten people from bharati vidyapeeth gym were selected randomly, age 23 to 26 years. For the purpose of establishing reliability of the data subject was asked to perform bicep curl of 4 sets 1st set 30 rep 2nd 3rd & 4th 15 rep each with 30sec rest in between sets. Second test (without occlusion) training was conducted after one week, proper rest was given to the working muscle (bicep). The test of left and right bicep was measured pre and post exercise (with and without) thera-band. O2 saturation level was measured using pulse Oximeter pre and post exercise (with and without) theraband. The average measurement of the various test conducted were as following left biceps pre workout ± 14.52, with occlusion training ± 14.91 and without occlusion training ± 14.67. The average measurement of right bicep pre workout ±14.68, with occlusion training ±15.02 and without occlusion training ±14.81. SpO2 pre workout ±97%, occlusion training ±97%, and without occlusion training ±96%. The result was formulate using one way ANOVAs. The result revealed that there was a significant difference between the three variables of the SpO2 F > Fcrit (F= 8.42 F crit = 3.35). While there was no significant difference found among the variables of left and right biceps. It was seen that restriction of blood flow caused increase in blood flow on the concentrated muscle group.
Utilization of Glycoprotein IIB/IIIA Receptor Antagonists in the Management of Acute Coronary Syndrome: Focus on Patient Characteristics and Formulary Decisions

This study described the utilization of glycoprotein IIB/IIIA inhibitors (GP IIB/IIIAs) in a tertiary-care center. Medical records of 316 patients receiving GP IIB/IIIA were reviewed. Patient demographics, medical history, coronary intervention, and outcomes were recorded and compared among groups based on specific GP IIB/IIIA used. The majority of GP IIB/IIIA was used for coronary interventions. Two patients died during hospitalization (1 tirofiban, 1 combination abciximab and tirofiban). Ten patients developed thrombocytopenia (5 tirofiban, 2 epti-fibatide). For coronary interventions, eptifibatide was the more economical therapy. For unstable angina and non-Q-wave myocardial infarction, tirofiban became the most economical therapy. Based on this data, a marginal cost saving of $676 per 316 patients would be achieved if abciximab and eptifibatide were used only. The selection of agents of choice in individual institutions should be based on data from clinical trials and pharmacoeconomic studies, as well as the institution-specific patient population and practice.
Significant wave height forecasting based on the hybrid EMD-SVM method

Prediction of significant wave height (SWH) is considered an effective method in marine engineering and prevention of marine disasters. Support vector machine (SVM) model has limitations in processing nonlinear and non-stationary SWH time series. Fortunately, empirical mode decomposition (EMD) can effectively deal with the complicated series. So, the SWH prediction method based on EMD and SVM is proposed by combining the advantages of both methods. A statistical analysis was carried out to compare the results of two models i.e., between the hybrid EMD-SVM and SVM. In addition, two models are used for forecasting SWH with 3, 6, 12 and 24 hours lead times, respectively. A high R value of different prediction times for the hybrid model. Results indicate that SWH prediction of the hybrid EMD-SVM model is superior to the SVM model.
The characterisation of WHIRLY1 functions in chloroplast development

Chloroplast biogenesis requires coordinated expression of plastome and nuclear genes. The single-stranded DNA binding protein, WHIRLY1 (WHY1), which is localised in chloroplasts and nuclei has important but poorly characterised roles in this process. WHY1 functions in barley chloroplast development were assessed in the base, middle and tip sections of two RNAi-knockdown lines (W1-1 and W1-7) with less than 5% of the wild type protein. RNA-seq analysis revealed that transcripts encoding photosynthetic proteins were highly expressed in the embryos of the dry seeds of the W1-7 compared to the wild type. The greening of the developing leaves was delayed in the WHY1-deficient seedlings relative to the wild type, with slower pigment accumulation and attainment of photosynthetic capacity in the WHY1-deficient leaves. However, the leaves of all lines reached a similar stage of chloroplast development at 14 days after germination. Transcript and metabolite profiling analysis showed changes in RNA and amino acid metabolism, TCA cycle, photosynthesis and photorespiration, particularly in the basal sections of the WHY1-deficient leaves. The expression of the plastid-encoded ribosomal genes was greatly increased in the WHY1-deficient lines, including transcripts involved in RNA processing such as pentatricopeptide repeat proteins, redox-associated proteins and transcription factors of the MYB, bHLH and WRKY families. The levels of transcripts encoding FAR1, Val-tRNA synthetase and chloroplast 50S and 30S ribosomal subunits were significantly higher in the basal sections of the W1-7 leaves than the wild type. The WHY1-deficient leaves had twice the amount of plastid DNA as the wild type. Nevertheless, plastome-encoded transcripts and proteins were significantly lower than the wild type. Conversely, the levels of nuclear-encoded photosynthetic transcripts and proteins were significantly higher that the wild type. Developing WHY1-deficient leaves showed aberrant splicing of plastid ribosomal RNAs of 23S and 4.5 ribosomal RNAs. The Arabidopsis WHY1 protein interacted with the RH22, which is required for the splicing of chloroplast rRNAs. The LEA5 protein was also shown to interact with RH22 in the chloroplasts. WHY1 therefore has multiple roles in chloroplasts. In particular, plastid-encoded ribosomal transcripts are not effectively translated into ribosomal subunits in the absence of WHY1 during early leaf development. WHY1 is required for the transcription and translation of plastome genes that are required for the transition from plastids to chloroplasts in the developing barley leaf.
Repurposing of mine waste: an alternative management approach to gold tailings in South Africa

i Statement of originality . ii Acknowledgments . iii Table of contents . iv List of figures . vii List of Tables . viii Acronyms and abbreviations . ix CHAPTER 1 .
Is Self-Reported Propensity for Everyday Illusions of Control Higher in Gamblers and Is It Associated With Gambling-Specific Erroneous Beliefs?

People who engage in gambling are known to hold erroneous views about the nature of gambling. One of the most commonly observed cognitive biases is the illusion of control, where people’s subjective appraisal of contingency between behavior and events is greater than the objective contingency. Such beliefs have been found to be strongest in problem gamblers and can lead to over-confidence in the ability to win money from gambling. A question, however, is whether such perceptions are (a) specific to gambling and whether gamblers display a tendency to over-estimate contingencies in everyday life and (b) if a tendency to endorse everyday illusion of control beliefs is related to specific gambling-related beliefs among those who gamble. Answers to these questions might provide insights into whether some people are potentially more vulnerable to beliefs that might have implications for gambling. An online sample of 788 adults completed a survey about simple everyday situations where people might attempt to exert control (e.g., pressing elevator buttons more often, throwing dice in games). The survey included a scale that captured everyday situations as well as established measures of illusion of control and superstition in gambling. The results showed that those who report greater control in everyday tasks scored higher on standardized measures of beliefs about chance and gambling-related cognitions relating to illusory control. Scores on both types of measures were higher in gamblers than non-gamblers. The findings suggest that gamblers may differ in how they generally perceive and respond to situations involving tasks largely dominated by chance or limited opportunities for genuine control.
Restoration of the Lost Map Area of the Underlying Image Surface Using the Reconstruction Method

The article presents a method for recovering lost sections of the map of the underlying surface. We consider spatial autocorrelation as image pre-processing for its subsequent analysis when restoring a part of the map in the direction of the radar carrier course. An algorithm for recovering images of lost areas has been proposed and a software implementing the algorithm has been developed. The efficiency of the developed algorithm has been evaluated on a test set of images using a statistical criterion.
Role of Farm Women in Sustainable Livelihood Pattern in Context of Information Needs

This study is to analyze information sources and information needs of women farmers of Banka and Bhagalpur district of Bihar. The research was undertaken for assessment of information needed for young farm women of age group of 18-35 years with respect to kharif paddy cultivation. Useful Information is the pivotal for successful kharif paddy cultivation. In the study area young farm women contribute immensely in kharif paddy cultivation. Information helps in creating awareness about technologies and mobilize people to use them. It also helps in training people, organizing community and ultimately resulting in the development of the whole nation. Result of the study illustrated that farm women need more information about selling of product, pest control, nursery raising and disease management. The study also revealed that the most preferred source of information was personal localite i.e. Husband, Friend, Relatives and Neighbors and agri-input dealers.
Exploring the relationship between ICT, SCM practices and organizational performance in agri-food supply chain

This paper presents the concerns in agri-food supply chain. Further the research investigates the role of information and communication technology (ICT) in agri-food supply chain and determines the impact of supply chain management (SCM) practices on firm performance. ,The theoretical framework was proposed for the study on the basis of existing literature. Data for the study was collected with the help of structured questionnaire from 121 executives and officers of the public food distribution agency. Partial least square (PLS)–structured equation modeling was employed to test the framework and hypotheses. ,The results indicate that ICT and SCM practices (logistics integration and supplier relationships) have a significant relationship. Furthermore, SCM practices (information sharing, supplier relationship and logistics integration) have a significant and positive impact on performance of the organization. ,Further research could be carried out to test the moderation effect of SCM practices between ICT and organizational performance (OP). Extending the research study to the companies operating in other sectors can enhance the external validity of the study and improve the accuracy of parameters examined. ,This study can be of interest to the agri-food industry as well as other industry practitioners interested in improving the performance of the organization from the view of supply chain. ,The outcomes of this study have important implications that translate into a series of recommendations for the management of public food distribution as well as other agri-food-based supply chains.
Non-Concentric Ladder Soil Model for Dynamic Rating of Buried Power Cables

This paper presents a new, non-concentric ladder soil model for dynamic rating of buried power cables. For both, deep and shallow burial, static isotherms within the soil form non-concentric cylinders around a single cable. These isotherms are used to design a non-concentric ladder soil model. For multiple cables, isotherms may have a complex shape, and heat capacities of the soil layers are calculated numerically. The new model gives precise dynamic rating results in excellent agreement with physical simulations based on the finite element method (FEM). It also allows to calculate temperature profiles within the soil surrounding the cable.
Phase I expansion trial of an oral TORC1/TORC2 inhibitor (CC-223) in nonpancreatic neuroendocrine tumors (NET).

e15004 Background: Clinical activity of everolimus, an allosteric TORC1-selective inhibitor, has been established in pancreatic NET. CC-223 is an ATP-competitive inhibitor of the mTOR kinase, inhibiting both TORC1 and TORC2 complexes. Methods: Following establishment of the MTD (reported at ASCO 2012), subjects with non-pancreatic NET and selected other tumors were enrolled in expansion cohorts of up to 20 evaluable subjects. CC-223 was dosed at 45 mg once daily in 28 day cycles until disease progression. Results: As of 09 January, 2013, 101 solid tumor subjects have been treated. Preliminary results from the NET cohort (n=23) are reported here. Subjects with non-pancreatic tumors of gut origin with progression within 12 months and receiving ongoing treatment with somatostatin analogs (SSA) were eligible. The majority of tumors were of midgut origin with liver metastases; 9 subjects had refractory carcinoid syndrome despite SSA use. The most common (> 20%) related adverse events (all grades) were stomatit.
Sustainable food, ethical consumption and responsible innovation: insights from the slow food and “low carbon food” movements in Taiwan

ABSTRACT This paper examines two food initiatives in Taiwan that address broad social concerns that have informed changes in activists’ perceptions of food citizenship in relation to globalization. Drawing on participant observation and in-depth interviews with stakeholders in two food movements, this ethnographic study contextualizes the motivations and meaning of “local” from the perspectives of social activists and food businesses in Taiwan. It investigates the strategies by which stakeholders engage consumers with the concept of local food as well as the limitations of that engagement, situating the concept of “local food” within sustainable consumption and local traditions. The findings illuminate how activists leverage global discourses on food movements and adapt them to local settings, blending with the vernaculars of local beliefs and traditional values. The study also discusses the potential and limits of this strategy and the use of new media technology in local food activism.
Evaluation of trends in diabetes care in a patient-centered medical home

Background: The patient-centered medical home (PCMH) is a model used in primary care to achieve effective management of chronic diseases. The Augusta University Health Family Medicine Center (AUFMC), a PCMH recognized by the National Committee for Quality Assurance, has implemented strategies to manage its patient population with diabetes. The present study evaluated the effects of these interventions through trend analysis of selected diabetic core measures by use of a qualified clinical data registry, the Practice Partner Research Network. Methods: For this retrospective study, de-identified data were abstracted for adult patients with diabetes for the period of 20132015. Process and outcome measures were determined for selected diabetic core measures, based on the 2015 American Diabetes Association and Physician Quality Reporting System of the Centers for Medicaid and Medicare (CMS). These measures included glycated hemoglobin (HbA1c), blood pressure (BP), low-density lipoprotein cholesterol (LDL), urine microalbumin (Um), diabetic foot and eye exams, and influenza and pneumococcal vaccinations. These values were analyzed by the CochranArmitage test for trends over time to determine the proportions of patients at the recommended goals. Results: Over time, there were increasing trends for patients who were at the goals for frequencies of HbA1c, Um, LDL, pneumococcal vaccinations, and diabetic retinal exams (p<0.01). Increasing trends were also evident for patients at goal values for HbA1c, BP, and LDL levels (p<0.01). Decreasing trends were noted, however, in the rate of diabetic foot exams (p<0.01). Conclusions: Since AUFMC achieved PCMH recognition status, efforts to improve the management of patients with diabetes have yielded positive outcomes and valuable lessons. Areas of strength include utilization of the diabetes registry, education by regular providers, tailored use of electronic health records for patient education and physician documentation, and appropriate utilization of all team members. Trend analysis indicated that targeted diabetic interventions contributed to improved outcomes in selected diabetic core measures.
Devastating Losses: How Parents Cope With the Death of a Child to Suicide or Drugs

This book fills a critical gap in our scientific understanding of the grief response of parents who have lost a child to traumatic death and the psychotherapeutic strategies that best facilitate healing. It is based on the results of the largest study ever conducted of parents surviving a child's traumatic death or suicide. The book was conceived by William and Beverly Feigelman following their own devastating loss of a son, and written from the perspective of their experiences as both suicide-survivor support group participants and facilitators. It intertwines data, insight, and critical learning gathered from research with the voices of the 575 survivors who participated in the study.
Effect of the Ethanolic Extract of Salvia officinalis on Ovarian Angiogenesis in Mice at Preimplantation: A Morphological and Molecular Analysis

Background: Salvia officinalis is a phytoestrogen, which is used to reduce clinical signs of pregnancy and improve the female infertility in herbal medicine treatment. The effect of S. officinalis on ovarian angiogenesis at the preimplantation time is unknown. Objectives: This research was a histomorphometric and quantitative real-time study on angiogenic activity in the ovarian tissue in mice after exposure to S. officinalis at preimplantaion. Methods: The extract of S. officinalis leaves, which was analyzed by phytochemical methods, administered at a dose of 100 mg/kg daily for 14 days to female mice. Then, pseudopregnancy was induced and ovarian tissue samples were removed for histological and molecular assessment. Results: Data analysis on the space-solid phase micro extraction/gas chromatography-mass spectrometry demonstrated�-thujone (33.90%), camphor (19.34%), cineole (11.01%) and s-thujone (9.48%) were the dominating compounds in the leaves of S. officinalis. Data analysis on histomorphometric parameters showed a significant difference in the vascular parameters between the test and control groups. Furthermore, gene expression analysis implied an increased level of the vascular endothelial growth factor (VEGF) (3.175) and was also associated with an increase in the level of Kinase insert domain protein receptor (KDR/Flk) gene expression (3.556) and FMS-like tyrosine kinase (Flt) gene expression (3.437) in the test group compared to the control group. Conclusions: Increased ovarian angiogenesis after exposure to S. officinalismayinduce vascular permeability and finally contribute to a variety of disorders including clinical signs similar to the ovarian hyperstimulation syndrome.