Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparison of Personal Video Technology for Teaching and Assessment of Surgical Skills.

Background Improvements in personal technology have made video recording for teaching and assessment of surgical skills possible. Objective This study compared 5 personal video-recording devices based on their utility (image quality, hardware, mounting options, and accessibility) in recording open surgical procedures. Methods Open procedures in a simulated setting were recorded using smartphones and tablets (MOB), laptops (LAP), sports cameras such as GoPro (SC), single-lens reflex cameras (DSLR), and spy camera glasses (SPY). Utility was rated by consensus between 2 investigators trained in observation of technology using a 5-point Likert scale (1, poor, to 5, excellent). Results A total of 150 hours of muted video were reviewed with a minimum 1 hour for each device. Image quality was good (3.8) across all devices, although this was influenced by the device-mounting requirements (4.2) and its proximity to the area of interest. Device hardware (battery life and storage capacity) was problematic for long procedures (3.8). Availability of devices was high (4.2). Conclusions Personal video-recording technology can be used for assessment and teaching of open surgical skills. DSLR and SC provide the best images. DSLR provides the best zoom capability from an offset position, while SC can be placed closer to the operative field without impairing sterility. Laptops provide best overall utility for long procedures due to video file size. All devices require stable recording platforms (eg, bench space, dedicated mounting accessories). Head harnesses (SC, SPY) provide opportunities for "point-of-view" recordings. MOB and LAP can be used for multiple concurrent recordings.
Perceived effectiveness of fear appeals in AIDS education: relationship to ethnicity, gender, age, and group membership.

A study was conducted with 261 community residents, college students, and intravenous drug users to investigate perceived effectiveness of fear appeals in AIDS education posters. Experimental posters with high-fear pictures portraying severe consequences of AIDS and low-fear posters that were neutral regarding disease severity were evaluated in terms of their perceived effectiveness in motivating people to use condoms. Posters also contained written messages communicating high and low levels of personal vulnerability and response efficacy. High-severity/fear posters were rated as significantly more effective than low-severity/fear posters (p less than .0001), but response efficacy and personal vulnerability were significant only in interaction with other variables (p less than .01). Age, gender, ethnicity, and group membership did not, in general, influence rated effectiveness. However, group membership and age were significant as interactions with severity/fear level and response efficacy, respectively (p less than .01). Subjects showed no differential preference for posters portraying individuals whose ethnicity was the same as their own. Findings confirmed previous research supporting the effectiveness of fear appeals and suggest that fear-oriented appeals may be effective in promoting changes in community norms and motivating individuals to adopt AIDS risk-reduction strategies.
Facial expression of pain: An evolutionary account

This paper proposes that human expression of pain in the presence or absence of caregivers, and the detection of pain by observers, arises from evolved propensities. The function of pain is to demand attention and prioritise escape, recovery, and healing; where others can help achieve these goals, effective communication of pain is required. Evidence is reviewed of a distinct and specific facial expression of pain from infancy to old age, consistent across stimuli, and recognizable as pain by observers. Voluntary control over amplitude is incomplete, and observers can better detect pain that the individual attempts to suppress rather than amplify or simulate. In many clinical and experimental settings, the facial expression of pain is incorporated with verbal and nonverbal vocal activity, posture, and movement in an overall category of pain behaviour. This is assumed by clinicians to be under operant control of social contingencies such as sympathy, caregiving, and practical help; thus, strong facial expression is presumed to constitute an attempt to manipulate these contingencies by amplification of the normal expression. Operant formulations support skepticism about the presence or extent of pain, judgments of malingering, and sometimes the withholding of caregiving and help. To the extent that pain expression is influenced by environmental contingencies, however, “amplification” could equally plausibly constitute the release of suppression according to evolved contingent propensities that guide behaviour. Pain has been largely neglected in the evolutionary literature and the literature on expression of emotion, but an evolutionary account can generate improved assessment of pain and reactions to it.
Maternal Environment Alters Renal Response To Angiotensin II In The Spontaneously Hypertensive Rat

1. The level of hypertension displayed by the adult spontaneously hypertensive rat (SHR) may be reduced by 20–30 mmHg if SHR pups are cross‐fostered to a normotensive dam at birth (SHRX). The mechanisms involved are largely unknown, but may involve the kidney and the renin–angiotensin system (RAS) because renal responses to angiotensin (Ang) II are enhanced in the SHR and brief blockade of the RAS in the young rat permanently lowers blood pressure in the SHR. Accordingly, the aim of the present study was to investigate the effect of cross‐fostering on the renal response to AngII in the SHR.
The sensations produced by electrical stimulation of the visual cortex

1. An array of radio receivers, connected to electrodes in contact with the occipital pole of the right cerebral hemisphere, has been implanted into a 52‐year‐old blind patient. By giving appropriate radio signals, the patient can be caused to experience sensations of light (‘phosphenes’) in the left half of the visual field.
Speckle Interferometry of Southern Double Stars. II. Measures from the CASLEO 2.15 Meter Telescope, 1995-1996

Relative astrometry is presented for 198 observations of 160 double stars. The data were obtained at the 2.15 m telescope at the Complejo Astronómico El Leoncito (Argentina) with a multianode microchannel array (MAMA) detector system. Five high-quality nondetections are also reported. When judged against ephemeris positions for binaries with very well determined orbits, the separation residuals exhibit a root mean square deviation of 13.2 mas and the position angle residuals exhibit rms deviation of 2. °9. Factors affecting the measurement precision are discussed.
The relationship between bone metabolism, melatonin and other hormones in sham-operated and pinealectomized rats.

OBJECTIVE The influence of pinealectomy and long-term melatonin (MEL) administration on circadian oscillations of selected biochemical markers of bone metabolism [serum alkaline phosphatase (ALP) activity, carboxyterminal propeptide type I procollagen (PICP) and carboxyterminal telopeptide type I collagen (ICTP) concentrations as well as urinary excretion of hydroxyproline (HYP) and Ca] and possible involvement of circadian secretion of IGF-I, parathyroid, thyroid, adrenal cortex and gonads function in this mechanism was evaluated. METHODS Studies were performed in 192 adult male Wistar rats weighing 145 +/- 9 g which were subjected to pinealectomy or sham operation. In half of the animals from each group MEL (Sigma, USA) in a dose of 50 mg/100 g b.w. was administered intraperitonealy (daily between 17.00 and 18.00 h for a 4-week period). Material for studies (blood and urine) was collected every 3 hours during a day. Hormones, PICP and ICTP concentrations were determined with the use of RIA methods. whereas ALP, HYP and Ca values - spectrophotormetrically. RESULTS The study has shown that pinealectomy had an inducing, while exogenous MEL a suppressing effect upon the level of investigated biochemical markers of bone metabolism. Furthermore, substantial changes in the values of amplitude and phase of their circadian oscillations were shown. Distinct, dependent on the time of day disturbances in circadian fluctuations of PICP, ICTP, HYP and Ca showing generally negative correlation with changes in endogenous MEL concentrations and positive with IGF-I and corticosterone (B) levels were found. In addition, changes in circadian oscillations of ALP and PICP correlated negatively with daily oscillations of calciotropic hormones and B. However, ICTP, HYP and Ca concentrations correlated positively with circadian fluctuations of B and FT3 (the latter only in sham operated rats receiving MEL). CONCLUSIONS This study showed that both pinealectomy and long-term MEL administration influence the circadian rhythm of bone metabolism and that an important role in the mechanism of this dependence is played by the changes of endogenous MEL levels. Secondary changes in circadian oscillations of calciotropic hormones, IGF-I and corticosterone concentrations, caused by pinealectomy and long-term MEL administration result in altered bone metabolism rhythm.
Growth hormone increases predation exposure of rainbow trout

The energetic state of an animal strongly influences decisions that balances feeding against predation risk. Growth hormone increases the metabolic demands, which should elevate the feeding motivation of an animal. This, in turn, may increase the willingness to risk exposure to predators during feeding. To test this hypothesis, we studied the effect of growth hormone on the behavioural response of rainbow trout (Oncorhynchus mykiss) to simulated attacks from a model heron. After attacks, growth hormone treated trout foraged closer to the water surface, resumed feeding earlier, and ate more food than did control trout. Such behaviour should increase the susceptibility to aerial predation. Thus, predation may select against high endogenous growth hormone secretion in wild fish. Furthermore, genetic manipulations to increase growth hormone levels, intended to improve growth performance in aquaculture, may result in individuals with substantially altered behavioural patterns. In light of the increasing potential for interactions between farmed and wild fish, growth hormone transgenic fish may pose a threat to wild fish populations.
Demonstrations of Efficient Online Spectrum Defragmentation in Software-Defined Elastic Optical Networks

Elastic optical networks (EONs) facilitate agile spectrum management in the optical layer. When coupling with software-defined networking, they function as software-defined EONs (SD-EONs) and provide service providers more freedom to customize their infrastructure dynamically. In this paper, we investigate how to overcome spectrum fragmentation in SD-EONs with OpenFlow-controlled online spectrum defragmentation (DF), and conduct system implementations to facilitate highly-efficient online DF. We first consider sequential DF, i.e., the scenario that involves a sequence of lightpath reconfigurations to progressively consolidate the spectrum utilization. We modify our previous DF algorithm to make sure that the reconfigurations can be performed in batches and the “make-before-break” scheme can be applied to all of them. The modified algorithm is implemented in an OpenFlow (OF) controller, and we design OF extensions to facilitate synchronous batch reconfiguration. Then, we further simplify the DF operations by designing and implementing parallel DF that can accomplish all the DF-related lightpath reconfigurations simultaneously. All these DF implementations are experimentally demonstrated in an SD-EON control plane testbed that consists of 14 stand-alone OF agents and one OF controller, which are all implemented based on high-performance Linux servers. The experimental results indicate that our OF-controlled online DF implementations perform well and can improve network performance in an efficient way.
Reverse remodelling in heart failure with cardiac resynchronisation therapy

This review examines the use of cardiac resynchronisation therapy (CRT) for chronic, severe, systolic heart failure. Left ventricular (LV) remodelling is the final common pathway of systolic heart failure and portends a poor prognosis. It is characterised by progressive LV dilatation, deterioration of ventricular contractile function and distortion of LV cavity shape. The LV remodelling process is triggered by prolonged pressure or volume overload, loss of contracting myocytes from myocardial infarction, genetic abnormalities of contractile proteins or exposure to cardiotoxic agents. Current therapeutic strategies for systolic heart failure aim to slow or halt the remodelling process. “Reverse remodelling” is a relatively new concept, where progressive LV dilatation and deterioration in contractile function are not simply arrested, but partially reversed. Cardiac resynchronisation therapy is a novel and effective treatment for systolic heart failure, and is associated with reverse remodelling of the LV.
Evaluating Impact of Rain Attenuation on Space-borne GNSS Reflectometry Wind Speeds

The novel space-borne Global Navigation Satellite System Reflectometry (GNSS-R) technique has recently shown promise in monitoring the ocean state and surface wind speed with high spatial coverage and unprecedented sampling rate. The L-band signals of GNSS are structurally able to provide a higher quality of observations from areas covered by dense clouds and under intense precipitation, compared to those signals at higher frequencies from conventional ocean scatterometers. As a result, studying the inner core of cyclones and improvement of severe weather forecasting and cyclone tracking have turned into the main objectives of GNSS-R satellite missions such as Cyclone Global Navigation Satellite System (CYGNSS). Nevertheless, the rain attenuation impact on GNSS-R wind speed products is not yet well documented. Evaluating the rain attenuation effects on this technique is significant since a small change in the GNSS-R can potentially cause a considerable bias in the resultant wind products at intense wind speeds. Based on both empirical evidence and theory, wind speed is inversely proportional to derived bistatic radar cross section with a natural logarithmic relation, which introduces high condition numbers (similar to ill-posed conditions) at the inversions to high wind speeds. This paper presents an evaluation of the rain signal attenuation impact on the bistatic radar cross section and the derived wind speed. This study is conducted simulating GNSS-R delay-Doppler maps at different rain rates and reflection geometries, considering that an empirical data analysis at extreme wind intensities and rain rates is impossible due to the insufficient number of observations from these severe conditions. Finally, the study demonstrates that at a wind speed of 30 m/s and incidence angle of 30°, rain at rates of 10, 15, and 20 mm/h might cause overestimation as large as ≈0.65 m/s (2%), 1.00 m/s (3%), and 1.3 m/s (4%), respectively, which are still smaller than the CYGNSS required uncertainty threshold. The simulations are conducted in a pessimistic condition (severe continuous rainfall below the freezing height and over the entire glistening zone) and the bias is expected to be smaller in size in real environments.
Heart rate variability during waking and sleep in healthy males and females.

STUDY OBJECTIVES The study goal was to investigate autonomic activity with heart rate variability analysis during different sleep stages in males and females. DESIGN The study utilized a 2 Groups (males, females) x 4 States (waking, stage 2 sleep, stage 4 sleep, rapid-eye movement sleep) mixed design with one repeated, within-subjects factor (i.e., state). SETTING The study was carried out in the sleep laboratory of the Thomas N. Lynn Institute for Healthcare Research. PARTICIPANTS Twenty-four healthy adults (fourteen females and ten males). INTERVENTIONS NA. MEASUREMENTS AND RESULTS All participants underwent polysomnographic monitoring and electrocardiogram recordings during pre-sleep waking and one night of sleep. Fifteen-minute segments of beat-to-beat heart rate intervals during waking, stage 2 sleep, stage 4 sleep, and REM sleep were subjected to spectral analysis. Compared to NREM sleep, REM sleep was associated with decreased high frequency (HF) band power, and significantly increased low frequency (LF) to (HF) ratio. Compared to females, males showed significantly elevated LF/HF ratio during REM sleep. Males also demonstrated significantly decreased HF band power during waking when compared to females. No significant sleep- or gender-related changes in LF band power were found. CONCLUSIONS The results confirmed changes in autonomic activity from waking to sleep, with marked differences between NREM and REM sleep. These changes were primarily due to stage-related alterations in vagal tone. REM sleep was characterized by increased sympathetic dominance, secondary to vagal withdrawal. The data also suggested gender differences in autonomic functioning during waking and sleep, with decreased vagal tone during waking and increased sympathetic dominance during REM sleep in the males.
Automatic learning algorithm for the MD-logic artificial pancreas system.

BACKGROUND Applying real-time learning into an artificial pancreas system could effectively track the unpredictable behavior of glucose-insulin dynamics and adjust insulin treatment accordingly. We describe a novel learning algorithm and its performance when integrated into the MD-Logic Artificial Pancreas (MDLAP) system developed by the Diabetes Technology Center, Schneider Children's Medical Center of Israel, Petah Tikva, Israel. METHODS The algorithm was designed to establish an initial patient profile using open-loop data (Initial Learning Algorithm component) and then make periodic adjustments during closed-loop operation (Runtime Learning Algorithm component). The MDLAP system, integrated with the learning algorithm, was tested in seven different experiments using the University of Virginia/Padova simulator, comprising adults, adolescents, and children. The experiments included simulations using the open-loop and closed-loop control strategy under nominal and varying insulin sensitivity conditions. The learning algorithm was automatically activated at the end of the open-loop segment and after every day of the closed-loop operation. Metabolic control parameters achieved at selected time points were compared. RESULTS The percentage of time glucose levels were maintained within 70-180 mg/dL for children and adolescents significantly improved when open-loop was compared with day 6 of closed-loop control (P<0.0001) and remained unaltered for the adult group (P=0.11) during nominal conditions. In varying insulin sensitivity conditions, the percentage of time glucose levels were below 70 mg/dL was significantly reduced by approximately sevenfold (P<0.001). These observations were correlated with significant reduction in the Low Blood Glucose Index (P<0.001). CONCLUSIONS The new algorithm was effective in characterizing the patient profiles from open-loop data and in adjusting treatment to provide better glycemic control during closed-loop control in both conditions. These findings warrant corroboratory clinical trials.
Cambios cognitivos en el envejecimiento normal : influencia de la edad y su relación con el nivel cultural y el sexo

En esta tesis se aborda el estudio del funcionamiento cognitivo en el envejecimiento normal desde una perspectiva neuropsicologica e integradora, y un cuidadoso control metodologico. Se trata de un estudio amplio y profundo, no solo por el numero de funciones estudiadas (velocidad de procesamiento, memoria, funciones visoperceptivas, visoespaciales, visoconstructivas, linguisticas, atencion y funciones ejecutivas), sino tambien por intentar apresar el estado de los principales componentes de cada funcion y el analisis de las relaciones que existen entre estos. Para ello se estudia una muestra limpia de participantes entre 65 y 75 anos, medica, funcional y neuropsicologicamente normales. Ademas, este trabajo pone de manifiesto la relevancia de los factores sexo, nivel educativo y nivel cultural a la hora de explicar la variabilidad cognitiva observada en el envejecimiento normal, asi como el importante papel modulador que muestran estas variables sobre los efectos de la edad en el funcionamiento cognitivo de los mayores sanos. Por ultimo, los resultados de este trabajo subrayan la importancia del nivel cultural como variable predictora del funcionamiento cognitivo normal en la vejez.
Prevalence and Correlates of Violence against Women in Nepal: Findings from Nepal Demographic Health Survey, 2011

Using data from a nationally representative sample of 3224 ever-married women interviewed as part of Nepal Demographic Health Survey—2011, this paper examined the prevalence and correlates of violence against women in Nepal. Results showed that one out of every two ever-married women aged 15 - 49 of the country experienced violence of any kind in their life. Odds of experiencing violence are higher among women of rural areas, women having low economic and educational status, and separated/divorced women. Having more children and alcohol consuming husbands also increase women’s chance of being victimised of violence in Nepal.
Re-Thinking Mining Waste through an Integrative Approach Led by Circular Economy Aspirations

Mining wastes, particularly in the form of waste rocks and tailings, can have major social and environmental impacts. There is a need for comprehensive long-term strategies for transforming the mining industry to move toward zero environmental footprint. “How can the mining industry create new economic value, minimise its social and environmental impacts and diminish liability from mining waste? ” This would require cross-disciplinary skills, across the social, environmental, technical, legal, regulatory, and economic domains, to produce innovative solutions. The aim of this paper is to review the current knowledge across these domains and integrate them in a new approach for exploiting or “re-thinking” mining wastes. This approach includes five key areas of social dimensions, geoenvironmental aspects, geometallurgy specifications, economic drivers and legal implications for improved environmental outcomes, and circular economy aspirations, which are aligned with the 10 principles of the International Council on Mining and Metals (ICMM). Applying circular economy thinking to mining waste presents a major opportunity to reduce the liability and increase the value of waste materials arising from mining and processing operations.
Nasal involvement in allergic asthma

Even since the late 19th century, a relationship has been suspected between upper airway disease and the subsequent development or aggravation of asthma symptoms. To date, it has been generally accepted that pathologic conditions of the upper airways, e.g. allergic rhinitis, chronic sinusitis and nasal polyposis, may influence the lower airways. However, the mechanisms underlying this relationship were, for a long time, poorly understood. Recently, evidence has been accumulating which indicates a systemic connection as one of the responsible mechanisms in nasobronchial crosstalk. In this review, the pathophysiologic and immunologic aspects of the interaction between upper and lower airways will be discussed.