Miracle-dz/UniFAR-FTUs huggingface dataset:
The Pharmacological Effect and Mechanism of Lanthanum Hydroxide on Vascular Calcification Caused by Chronic Renal Failure Hyperphosphatemia

Objective The present work aimed to explore the efficacy of lanthanum hydroxide in managing the vascular calcification induced by hyperphosphate in chronic renal failure (CRF) as well as the underlying mechanism. Methods Rats were randomly allocated to five groups: normal diet control, CKD hyperphosphatemia model, CKD model treated with lanthanum hydroxide, CKD model receiving lanthanum carbonate treatment, together with CKD model receiving calcium carbonate treatment. The serum biochemical and kidney histopathological parameters were analyzed. The aortic vessels were subjected to Von Kossa staining, CT scan and proteomic analysis. In vitro, the calcium content and ALP activity were measured, and RT-PCR (SM22α, Runx2, BMP-2, and TRAF6) and Western blot (SM22α, Runx2, BMP-2, TRAF6, and NF-κB) were performed. Results In the lanthanum hydroxide group, serum biochemical and kidney histopathological parameters were significantly improved compared with the model group, indicating the efficacy of lanthanum hydroxide in postponing CRF progression and in protecting renal function. In addition, applying lanthanum hydroxide postponed hyperphosphatemia-mediated vascular calcification in CKD. Furthermore, lanthanum hydroxide was found to mitigate vascular calcification via the NF-κB signal transduction pathway. For the cultured VSMCs, lanthanum chloride (LaCl3) alleviated phosphate-mediated calcification and suppressed the activation of NF-κB as well as osteo-/chondrogenic signal transduction. Lanthanum hydroxide evidently downregulated NF-κB, BMP-2, Runx2, and TRAF6 expression. Conclusion Lanthanum hydroxide protects against renal failure and reduces the phosphorus level in serum to postpone vascular calcification progression.
Talking about my generation : comment les valeurs façonnent la consommation de luxe

En matière de luxe, les jeunes consommateurs cèderaient plus facilement aux sirènes de la contrefaçon que leurs aînés du fait de revenus plus faibles et de différences de valeurs. Nous le contestons en étudiant le cas des Emirats Arabes Unis, dont les nationaux présentent un égal accès au luxe, mais diffèrent en termes de valeurs suivant qu’ils sont nés avant ou après le boom économique fulgurant des années 1990. S’appuyant sur les théories fonctionnelles des attitudes, nous montrons que la consommation de luxe ne remplit pas les mêmes fonctions psychologiques pour les cohortes générationnelles nées avant le boom (avant 1990) ou après, et soulignons l’influence des valeurs dans l’arbitrage entre luxe authentique et luxe contrefait. Les valeurs expliquent ainsi à la fois l’influence négative de l’âge sur la consommation de contrefaçon dans les pays occidentaux et son influence positive dans le Golfe. Ces résultats permettent de formuler des recommandations pour les managers du luxe et les décideurs publics opérant dans le Golfe.
Cognitive consequences of metabolic disorders

Introduction and objective. Metabolic disorders are associated with a number of negative health consequences. Therefore, the aim of this review was to define the relationships between overweight and obesity, lipid metabolism disorders, hypertension, disorders of carbohydrate metabolism, and cognitive functions. Abbreviated description of the state of knowledge. Metabolic disorders may be linked to the reduction of cognitive functions, such as memory, abstract reasoning, verbal fluency, attention and psychomotor speed. Obesity may lead to changes in the hippocampus, one of the main structures involved in learning and memory. The evidence reviewed suggests that obesity, by inducing inflammation, leads to the dysfunction of brain structures such as the frontal cortex and corpus callosum involved in plasticity processes and cognitive functions. In addition, obesity has been found to be associated with abnormalities in the white matter and glial cells in the brain, which may also cause reduction in processing speed. It is possible that there is a non-linear relationship between lipids and cognitive function moderated by age and the proinflammatory process. Disturbances in carbohydrate metabolism can also lead to cognitive impairment, such as: memory, verbal fluency or abstract reasoning. Conclusions. Metabolic disorders are associated with a higher risk of developing cognitive impairment. This association can be moderated by additional factors: lifestyle, oxidative stress, pro-inflammatory processes, genetic factors, age and education.
Feedbacks between a non-Newtonian upper mantle, mantle viscosity structure and mantle dynamics

Previous studies have shown that a low viscosity upper mantle can impact the wavelength of mantle flow and the balance of plate driving to resisting forces. Those studies assumed that mantle viscosity is independent of mantle flow. We explore the potential that mantle flow is not only influenced by viscosity but can also feedback and alter mantle viscosity structure owing to a non-Newtonian upper-mantle rheology. Our results indicate that the average viscosity of the upper mantle, and viscosity variations within it, are affected by the depth to which a non-Newtonian rheology holds. Changes in the wavelength of mantle flow, that occur when upper-mantle viscosity drops below a critical value, alter flow velocities which, in turn, alter mantle viscosity. Those changes also affect flow profiles in the mantle and the degree to which mantle flow drives the motion of a plate analogue above it. Enhanced upper-mantle flow, due to an increasing degree of non-Newtonian behaviour, decreases the ratio of upper- to lower-mantle viscosity. Whole layer mantle convection is maintained but upper- and lower-mantle flow take on different dynamic forms: fast and concentrated upper-mantle flow; slow and diffuse lower-mantle flow. Collectively, mantle viscosity, mantle flow wavelengths, upper- to lower-mantle velocities and the degree to which the mantle can drive plate motions become connected to one another through coupled feedback loops. Under this view of mantle dynamics, depth-variable mantle viscosity is an emergent flow feature that both affects and is affected by the configuration of mantle and plate flow.
Deep matrix factorization based on self-attention mechanism for student grade prediction

Deep learning is gradually emerging in the field of educational data mining. Aiming at student grade prediction in education data mining, a prediction model combining self-attention mechanism and deep matrix factorization (ADMFN) is proposed. It can quickly extract important features of sparse data and process complex nonlinear data. Firstly, the student and course vector corresponding to the score matrix are input into the model and projected to obtain the potential feature vector of the student (course). Then, the potential feature vectors of students (courses) are added into the self-attention mechanism to construct a multi-layer perceptron network. Finally, by constructing a bilinear pooling layer, the output vectors of rows and columns are fused to obtain the predicted value of the score. We compare the existing recommendation system baselines to evaluate our model. The experimental results show that the proposed model is effective in real dataset.
Phytochemical composition, antioxidant and wound healing activities of Teucrium polium subsp. capitatum (L.) Briq. essential oil

ABSTRACT Teucrium poliumis widely used in Algerian folk medicine as to treat wounds. The aim of this study was to evaluate the chemical composition, antioxidant and wound healing properties of Teucrium polium essential oil. The composition was obtained by a combination of GC-FID and GC-MS analyses. The antioxidant activity was evaluated by in vitro assays (total antioxidant capacity, DPPH and bleaching of β-carotene). The in vivo wound healing potential of an ointment containing 10% of T. polium essential oil was investigated. The main components were in this order: β-pinene, germacrene, α-pinene, myrcene, limonene, bicyclogermacrene, trans-β-guaiene, spathulenol and β-bourbonene. Teucrium polium essential oil displayed a moderate antioxidant activity. The in vivo experiments showed that 10% OEO accelerated the wound healing process in comparison with controls. This study provides a scientific rationale for the use of Teucrium polium essential oil in the treatments of wounds.
EVALUATION OF WEEPING WALL EFFICIENCY OF SOLID LIQUID SEPARATION

The objectives of this project were to evaluate the effectiveness of a settling basin with large dewatering surface area (weeping wall separation system) in removing total solids (TS) and fixed solids (FS) and to characterize particle size and nutrient content of influent and effluent streams. The study was conducted on an 1100 cow commercial dairy in California. A total of 350 influent and 77 effluent samples were obtained from a total of 20 flushes collected over four sampling periods. Influent mean percent TS concentrations within a flush were variable and ranged from 0.37 +/- 0.01% to 1.95 +/- 0.67% TS for an overall influent TS mean of 1.52 +/- 0.53% TS. Fixed solids ranged from 37.02 +/- 1.02% to 45.92 +/- 2.88% of TS. The corresponding values for TS concentration in effluent samples were less variable and ranged from 0.46 +/- 0.03% to 0.71. 0.26% TS and FS ranged from 37.68 +/- 1.91 to 43.47 +/- 1.11% of TS. Percent of TS removed was 63.41%, 59.65%, 63.07%, and 49.29% for each sampling period. Mean electrical conductivity of influent and effluent samples was not different 4.33 +/- 0.37 and 4.16. 0.23 mS cm-1, respectively. Particle size fractionation was conducted on 39 influent and 15 effluent samples. Screen sizes were 2, 1, 0.5, 0.25, 0.125 mm. Percent of influent TS retained on each screen was 10.48, 12.26, 13.80, 14.27 and 18.28, respectively (30.90% of influent TS passed through the 0.125-mm screen). Percent of effluent TS retained on each screen was 0.63, 1.79, 3.45, 5.43, and 8.18, respectively (80.51% of effluent TS passed through the 0.125-mm screen). Although mass was removed by the separation system the nutrient concentrations of soluble elements (NH4-N+, K, P, Ca, Mg, Na, and Cl) in representative influent (n = 14) and effluent (n = 4) samples were not different. Concentration of organic-N was not different between select influent (184 +/- 49) and effluent (223 +/- 46) samples analyzed.
Biosensor technology in diagnostics and mechanistic studies of epilepsy

: Epilepsy is represented by a set of neurological disorders that result in recurring seizures and convulsions. Although several types of the condition have been characterized, the underlying cause for these remains largely unknown. A number of molecular biomarkers for epilepsy have been identified including glutamate, γ -aminobutyric acid, and miRNAs. In addition, a special role appears to be played by the potassium cation. Detection of these species is anticipated to assist in both diagnosis and fundamental understanding of the condition. This review details the application of a number of biosensor devices that have been designed specifically for the detection of both molecular biomarkers and the K + cation in proximity to an animal cortex. These devices offer considerable potential not only for diagnostic goals, but also for study of the cause and spread of the epileptic seizure, especially if such biosensors can detect analytes in a multiplexed, real-time manner.
Implementing process improvement initiative: the role of visualisation and standardisation methods

Purpose: Due to the difficulties organisations face in implementing process improvement initiatives (PIIs), this research explores how visualisation and standardisation of business processes help organisations achieve PIIs to improve organisational performance. Design and methodology: A multi-staged case study strategy that analyse qualitative data and performs a process modelling analysis of quantitative data. Findings: The paper makes two main contributions to existing knowledge. Firstly, it explains how taking the visualised and standardised methods on a PIIs can reduce service delivery times and enhance organisational performance. Secondly, it demonstrates how adopting these dual methods offers a better chance of increasing organisational performance than using only a single method. Research limitations: Although the paper considers the flexibility in the standardisation of business processes as it gives scope for innovation and creativity on the part of the process, it did not consider if flexibility is possible without breaking the standardised working way. Hence, future research can consider this. Also, future research can hypothesise the BPM model and test for statistical generalisability. Originality: The research offers new insight into how and when both visualisation and standardisation of PIIs can benefit organisations.
Dissociation of OCS upon various S(2p) Auger decay transitions

Dissociation of OCS upon various Auger decay transitions due to ionization at S(2p) threshold is studied. It is observed that the dissociation channels and their branching ratios vary with the binding energy of the Auger decay state. The kinetic energy release distribution (KERD) upon fragmentation of the molecule for various Auger transitions have also been studied.
Diagnosing Soft Tissue Sub-Surface Masses Using the XCS Classification System

Introduction: One of the most common types of cancer is breast cancer, which is considered as the second leading cause of death in women in Iran. Due to the fatality of this type of cancer, it is very important to diagnose the disease in the early stages and starting the treatment process. One of the methods to diagnose breast cancer is using mechanical arms (robot manipulator) to touch and measure the force in terms of displacement at the site of the breast touch by the robot. The hardness of the cancer tissue can affect the force diagram in terms of displacement, which can be used as a diagnostic method. The present study was performed to prepare a simulation model of breast soft tissue behavior considering subsurface masses. Then, a proposed classification system was designed to fit it. Material and Methods: In this section, first, the soft tissue behavior of the breast is simulated by considering sub-surface masses. The simulations are performed for a piece of tissue that is in the shape of a rectangular cube, as well as different dimensions of a spherical mass that is located at different depths and coordinates. Using simulation, various force-displacement diagrams have been obtained, based on which a data network. Results: The displacement force diagram for different modes is obtained using simulation. By giving the resulting diagrams to the trained system, the size and depth of the mass is determined. By comparing the obtained results with the initial model and the actual size and depth of the mass, a very good conformity is observed, which indicates the correct operation of the designed system and the performed simulation process. Conclusion: The proposed design system was used to diagnose the presence of tumors in tissue with sub-surface mass. The results show a high percentage of this method in diagnosis. However, the accuracy of this method can be greatly increased by increasing the amount of data given to the XCS system for training. On the other hand, instead of simulation data, test data on healthy and unhealthy people can be used for training.
Kinetic nucleation theory: A new expression for the rate of homogeneous nucleation from an ideal supersaturated vapor

The ‘‘kinetic theory’’ of homogeneous nucleation developed by Katz and Wiedersich is extended to derive a new expression for the rate of nucleation from an ideal supersaturated vapor. Compared to the classical expression for the nucleation rate, the new expression has a slightly different dependence on supersaturation, and a substantially different dependence on temperature. A comparison of the new expression with experimental data on nucleation rates of several organic liquids indicates that in some but not all cases the new expression gives much closer agreement with the data than does the classical expression. Discrepancies between the theory and the data are ascribed mainly to the physical assumptions of the theory presented, which are the same as in the classical theory—particularly, that the physical properties of microscopic clusters are the same as those of the bulk liquid.
Deep learning based question answering system in Bengali

ABSTRACT Recent advances in the field of natural language processing has improved state-of-the-art performances on many tasks including question answering for languages like English. Bengali language is ranked seventh and is spoken by about 300 million people all over the world. But due to lack of data and active research on QA similar progress has not been achieved for Bengali. Unlike English, there is no benchmark large scale QA dataset collected for Bengali, no pretrained language model that can be modified for Bengali question answering and no human baseline score for QA has been established either. In this work we use state-of-the-art transformer models to train QA system on a synthetic reading comprehension dataset translated from one of the most popular benchmark datasets in English called SQuAD 2.0. We collect a smaller human annotated QA dataset from Bengali Wikipedia with popular topics from Bangladeshi culture for evaluating our models. Finally, we compare our models with human children to set up a benchmark score using survey experiments.
Crystal structure of bis(dimethylammonium) hemi[1,2-bis(hydrogen 1,3-dicarboxylatophenyl)diazene] hemi[1,2-bis(hydrogen 1,3-dicarboxylatophenyl) diazene oxide], [C2H8N]2[C16H8N2O8]0.5[C16H8N2O9]0.5

C20H24N4O8.50, triclinic, P1 (no. 2), a = 6.1427(8) Å, b = 8.390(1) Å, c = 11.021(1) Å, * = 75.449(1)°, ) = 88.374(1)°, ' = 88.953(2)°, V = 549.5 Å, Z = 1, Rgt(F) = 0.048, wRref(F ) = 0.112, T = 293 K
Using Systematic Synthetic Phonics to Accelerate Rural Indigenous Children’s Acquisition of Early Literacy Skills

Studies focusing on the strategy of phonics in Malaysia have highlighted the insufficiency and ineffectiveness of SBELC phonics training received by teachers, resulting in confusion among them as to what really constitutes effective use of the phonics strategy. On the other hand, systematic synthetic phonics (SSP) has been proven beneficial in accelerating the performance of children in their early literacy. However, few studies have been conducted on English language learners as the majority of those research was focused on native speakers of the English language. Against this background, this article presents a description of a systematic way of teaching phonics that could inform teachers on how the strategy can be optimally utilised to accelerate the performance of students who are possibly at risk of being left behind. It then reports an investigation that compared the efficacy of SSP against SBELC phonics in accelerating the acquisition of early literacy skills with a group of indigenous children residing in the rural parts of Sarawak, Malaysia. Five instruments; (1) productive letter-sound test, (2) free-sound isolation test, (3) reading test, (4) spelling test, and (5) oral-reading fluency test were administered to measure phonemic awareness, decoding, reading, and spelling ability. Data were collected from the pretest and the posttest. The results demonstrate that both groups recorded significant improvement in reading and spelling, but children in the experimental group (SSP) outperformed the control group (SBELC phonics) significantly. Following this, SSP should be implemented in classrooms to help accelerate children’s early reading fluency and spelling ability. https://doi.org/10.26803/ijlter.19. 10.1
Data-Driven Approach for Incident Management in a Smart City

Buildings in Lisbon are often the victim of several types of events (such as accidents, fires, collapses, etc.). This study aims to apply a data-driven approach towards knowledge extraction from past incident data, nowadays available in the context of a Smart City. We apply a Cross Industry Standard Process for Data Mining (CRISP-DM) approach to perform incident management of the city of Lisbon. From this data-driven process, a descriptive and predictive analysis of an events dataset provided by the Lisbon Municipality was possible, together with other data obtained from the public domain, such as the temperature and humidity on the day of the events. The dataset provided contains events from 2011 to 2018 for the municipality of Lisbon. This data mining approach over past data identified patterns that provide useful knowledge for city incident managers. Additionally, the forecasts can be used for better city planning, and data correlations of variables can provide information about the most important variables towards those incidents. This approach is fundamental in the context of smart cities, where sensors and data can be used to improve citizens’ quality of life. Smart Cities allow the collecting of data from different systems, and for the case of disruptive events, these data allow us to understand them and their cascading effects better.
Noncovalent fabrication and electrochemical capacitance of uniform core–shell structured polyaniline–carbon nanotube nanocomposite

Highly uniform core–shell structured polyaniline–multiwall carbon nanotube nanocomposites have been successfully prepared by noncovalent coating of a polyaniline shell on the wall of MWNTs with the assistance of 1-pyrenesulfonic acid. It is found that 1-pyrenesulfonic acid plays important roles in dispersing MWNTs and directing the polymerization of the polyaniline shell by the sulfonic groups. The obtained nanocomposites exhibit a higher specific capacitance. This research provides a new approach for designing core–shell hybrid materials with potential application in high-performance electrochemical supercapacitors.
A CRIMINALIZAÇÃO ANDROCENTRISTA DA REVISTA ÍNTIMA DAS MULHERES EM PRESÍDIOS: A PUNIÇÃO LATENTE.

O presente estudo aborda a pratica da revista intima das mulheres visitantes em presidios brasileiros a partir de nocoes provenientes da criminologia feminista, associada ao conceito de lei penal latente.Para tanto, primeiramente, analisa-se os principais paradigmas criminologicos que possibilitaram o surgimento da criminologia feminista, chegando a conclusao de que o androcentrismo, denunciado pela mesma, sofre influencias do positivismo criminologico, orientando a criminalizacao (e vitimizacao) das mulheres muito mais pelo papel que assumem (ou tentam) na sociedade do que propriamente pelo que fazem.A partir dai, com o estudo da lei penal latente, constata-se que esta causa criminalizacoes e, por decorrencia, punicoes penais, que se escondem em demais campos juridicos, exatamente para se esquivar das garantias prometidas pelo Direito Penal.Apos, foi estudado a regulamentacao legal da pratica da revista intima – em especial no Estado de Minas Gerais – e, apos, constatado a existencia de lei federal proibindo a pratica (Lei 13.271/16). Com isto, questionou-se a razao de referida lei ser cumprida tao somente em relacao aos homens visitantes.A conclusao foi que a regulamentacao legal da revista intima e uma criminalizacao latente que, embora proibida por lei federal, e praticada com as mulheres em virtude do androcentrismo.