Miracle-dz/UniFAR-FTUs huggingface dataset:
Starbucks’ marketing communications strategy on Twitter

Abstract Many scholars have found that social media are extraordinarily useful platforms for marketers to engage their stakeholders. Much research has developed frameworks for and proposed empirical guidelines on how brands should communicate and interact with audiences on social media platforms. However, a comprehensive study that is based on a successful and reputable brand is still lacking. The objective of this research was to categorise the types of content used by one of the most admired brands in the world, Starbucks, and evaluate its effectiveness on Twitter. In total, the author studied 565 tweets and retweets and 1392 replies. This research found that Starbucks’ marketing communications strategy includes three types of original and retweeted content: information-sharing, emotion-evoking, and action-inducing content. The author also found six types of replies: information, Apology and suppot, positive comment, question and enquiry, chit-chat, and gratitude. To be successful on the social media platforms, this research suggests that brands should use various types of content, focus on visual content, and prepare for and manage customer interactions appropriately. The findings present useful and practical information for brands that seek to engage audiences using an inexpensive but compelling marketing communications strategy on social media.
SIMPLE estimate of the free energy change due to aliphatic mutations: Superior predictions based on first principles

The bioinformatics revolution of the last decade has been instrumental in the development of empirical potentials to quantitatively estimate protein interactions for modeling and design. Although computationally efficient, these potentials hide most of the relevant thermodynamics in 5‐to‐40 parameters that are fitted against a large experimental database. Here, we revisit this longstanding problem and show that a careful consideration of the change in hydrophobicity, electrostatics, and configurational entropy between the folded and unfolded state of aliphatic point mutations predicts 20–30% less false positives and yields more accurate predictions than any published empirical energy function. This significant improvement is achieved with essentially no free parameters, validating past theoretical and experimental efforts to understand the thermodynamics of protein folding. Our first principle analysis strongly suggests that both the solute–solute van der Waals interactions in the folded state and the electrostatics free energy change of exposed aliphatic mutations are almost completely compensated by similar interactions operating in the unfolded ensemble. Not surprisingly, the problem of properly accounting for the solvent contribution to the free energy of polar and charged group mutations, as well as of mutations that disrupt the protein backbone remains open. Proteins 2007. © 2007 Wiley‐Liss, Inc.
A JEB CLASSIC ON FISH EXERCISE

[Figure][1] Tobias Wang and Hans Malte discuss the 1977 paper by Joe W. Kiceniuk and David R. Jones entitled: ‘The oxygen transport system in trout ( Salmo gairdneri ) during sustained exercise. ’ A copy of the paper can be obtained from <http://jeb.biologists. org/content/69/1/247.
Prevalence of asymptomatic carotid atherosclerotic lesions detected by high-resolution ultrasonography and its relation to cardiovascular risk factors in the general population of a Japanese city: the Suita study.

BACKGROUND AND PURPOSE Because extracranial carotid atherosclerotic lesions have been considered rare, no reports have been published on the prevalence and distribution of these lesions in a general Japanese population. However, recent changes in lifestyle are thought to have caused an increase in these lesions. The aim of this study was to use high-resolution ultrasonography to examine the prevalence of asymptomatic extracranial carotid artery lesions and its relation to cardiovascular risk factors in an urban Japanese population. METHODS The subjects were 814 men and 880 women aged 50 to 79 years randomly sampled from the residents of Suita, a city located in the second largest urban area of Japan. Asymptomatic carotid lesions were detected and evaluated by a single physician with high-resolution B-mode ultrasonography. RESULTS We found significant sex differences in the prevalence of atherosclerotic lesions in the extracranial carotid artery; 4.4% of all the subjects, 7.9% of the men, and 1.3% of the women had atherosclerosis accompanied by stenosis of >50%. A strong association between these lesions and the results of a 75-g oral glucose tolerance test was found in both sexes. Multiple regression analysis of carotid atherosclerosis showed significant relationships with age, systolic blood pressure, fasting blood glucose, pack-years of smoking, total serum cholesterol, and HDL cholesterol in men (P<.05) and significant relationships with age, systolic blood pressure, pack-years of smoking, and total serum cholesterol in women (P<.05). CONCLUSIONS Our data showed that cardiovascular risk factors were strongly related to carotid atherosclerosis and that the proportion of severe carotid atherosclerosis with >50% stenosis was not low and was almost equal to that reported in developed western countries.
Research on the Service Demand Identification and Integration of Regional Science & Technology Resource Sharing Platform

Regional science technology resource sharing platform serves the regional innovation and entrepreneurship activities,and constantly provides effective support for innovation driving development strategy implementation. In the face of the evolution trend from"resource-oriented"to"demand-oriented"of sharing platform service,the classified acquisition methods of sharing platform service demand are given; Then,the sharing platform service demand is carried on multi-dimensional identification from user dimension,resource dimension and service dimension; After that,according to the service demand decomposition and priority principle,the integration process and integration modes of sharing platform service demand are designed including general demand,key demand,major demand. The research provides method guidance and decision-making basis for improving the service efficiency and service level of regional science technology resource sharing platform.
Multi-level current reinjection in double-bridge self-commutated current source conversion

A new self-commutated current source converter is proposed, based on the reinjection of multi-level dc current pulses via a GTO-switched multi-tapped interphase reactor. The ideal reinjection waveform for complete elimination of the harmonic content of the ac system side current is derived and a practical approximation proposed to increase the pulse number of the double-bridge converter to any multiple of twelve. A 48-pulse configuration is analyzed in detail to show the new concept effectiveness on both the ac and dc sides of the converter.
The Influence of Relational Demography and Guanxi : the Chinese Case

Two studies were conducted to investigate the indigenous concept of guanxi and its applications in the Chinese context. Guanxi refers to the existence of direct particularistic ties between an individual and others. We relate the concept to the idea of relational demography, which refers to similarities or differences between an individual and others on such factors as age, gender, race, religion, education, and occupation. The two studies focused on the importance of guanxi and relational demography in Chinese employment settings. In study 1, their importance was examined in a sample of 560 vertical dyads (i.e., between supervisor and subordinate) in Taiwan. In study 2, the effects were analyzed in a sample of 205 horizontal dyads, specifically between business executives and their important business connections (e.g., key customers, suppliers, bankers, government officials) in mainland China. Results support the importance of both guanxi and relational demography for subordinate trust in the supervisor, but only guanxi is found to be (extremely) important for business executives' trust in their connections. Implications for future cross-cultural research on the effect of common ties are discussed.
WDM optical packet ring performance insights: Scheduling and capacity

This paper addresses WDM optical packet rings which present a single control channel and multiple data channels. These rings are intended as transport networks in metro areas, i.e. are considered as replacement for the traditional SONET/SDH or Ethernet rings. These networks are thus expected to deliver a lossless and low latency service. In the considered transfer mode, time is slotted, traffic insertion is opportunistic and transit traffic always has priority over new traffic which ensures optical transparency. The present work assesses the impact on delay performance of the two configuration characteristics of these rings: scheduling mechanism and number of data channels. We compare two Max-Weight scheduling policies (Oldest Packet First, OPF and the originally proposed Largest Virtual Waiting Time First, LVWTF) with the commonly used, non Max-Weight, Round-Robin (RR) scheduling in order to assess the respective Fairness performances of LVWTF and RR. It is shown that unless the ring is heavily loaded, RR is as fair, or fairer than LVWTF. In the second part of the paper, we have analyzed the performance of an optical packet ring with uniform and complete traffic matrix configured with LVWTF scheduling. The mean delay performance is quantified, and shown to depend both on the number of data channels and on the number of nodes in the ring. In particular, it is shown that for a given number nodes, and a given load, the delay presents a minimum for a finite number of data channels, which shows that increasing resources (number of data channels) may indeed degrade QoS (delay).
NP-COMPLETENESS OF A COMBINATOR OPTIMISATION PROBLEM

Using the combinators S, K, I, B, C, S', B' and C', together with a rewrite system for a graph representation of combinator expressions such that reduction of a duplicator causes the duplicated expression to be "shared", we consider expressions in that combinatory logic which reduce to normal form. To each such expression we assign a weighting which is the number of reduction steps necessary to reduce the expression to normal form. Two expressions are considered equivalent if they represent the same lambda expression. The problem of minimising the number of reduction steps over equivalent combinator expressions is proved to be NP-complete. Abstract: Using the combinators S, K, I, B, C, S', B' and C', together with a rewrite system for a graph representation of combinator expressions such that reduction of a duplicator causes the duplicated expression to be "shared", we consider expressions in that combinatory logic which reduce to normal form. To each such expression we assign a weighting which is the number of reduction steps necessary to reduce the expression to normal form. Two expressions are considered equivalent if they represent the same lambda expression. The problem of minimising the number of reduction steps over equivalent combinator expressions is proved to be NP-complete.
Does House Rent Impede Mobility in the Temporary or Non-regular Labor Market?

This study analyzes whether house rent impedes labor mobility when there are job opportunities for temporary workers and non-regular employees at great distances. I also examine whether owned houses and public housing decrease labor mobility. The number of temporary workers has increased in many developed countries in recent years. The house rent and the related guarantee make it difficult to rent an apartment for temporary workers and non-regular employees. Little is known about the effect of house rent on the labor market, especially for temporary and non-regular employees, although empirical studies have analyzed the effect of the housing price or tenure of dwelling on labor mobility many times. Further, previous studies about labor mobility in Japan, not limited to house rent, use only macro data. Therefore, I use quasi-individual data to estimate the above issues. House rent especially discourages migration when there are job opportunities for arbeit workers and temporary workers, but not for short-time workers. Further, this effect is greater in the case of migration from 2005 to 2010 than for migration from 1995 to 2000. However, providing housing assistance by way of public housing decreases migration mobility, especially in the case of houses owned by the Urban Renaissance Agency and housing corporations.
Antioxidants – the case for fruit and vegetables in the diet

Compelling chemical, biochemical, clinical and epidemiological evidence supports the view that the antioxidant nutrients exert vital contributions towards the prevention or delayed onset of cancer and cardiovascular disease. The presence of antioxidants in fruit, vegetables, tea and red wine may help to explain why their presence in the diet is associated with reduced incidence of heart disease and cancer.
Effect of portal venous blood flow diversion on portal pressure.

To anticipate the hepatic vascular response to portacaval anastomosis, we studied portal pressure during diversion of portal blood through a temporary extracorporeal umbilical vein to saphenous vein shunt. The relationship of portal pressure to shunted flow was approximately linear. In five schistosomiasis patients (controls) portal diversion to 1,250 ml/min gave portal pressure-shunted flow curve slopes ranging from 0.13 to 0.57 cm water/100 ml per min (0.31+/-0.18, mean+/-SD). In 17 cirrhotic patients with portal hypertension a continuum of slopes was observed from within mean+/-2 SD of control (type A) to larger slopes (type B) indicating failure of portal pressure regulation. When portal flow was augmented by shunting from saphenous vein to portal vein, cirrhotic patients who had slopes less than mean+/-2 SD of controls during diversion (type A) exhibited a compliant system with small increases in portal pressure, whereas type B patients had significantly greater pressure increases. Selective investigations suggested that changes in portal pressure provoked compensatory changes in hepatic arterial blood flow that tended to maintain portal pressure at a set point. Type B patients demonstrated failure of this mechanism to varying degrees.After end-to-side portacaval shunt, seven type A cirrhotic patients maintained residual intrahepatic venous pressure unchanged from prior portal pressure, whereas six type B patients had a significant decrease. Residual intrahepatic venous pressure was measured after portacaval shunt in 40 cirrhotic patients who were followed for as long as 9 yr (median survival 4.0 yr). The 13 patients who developed chronic encephalopathy had significantly lower pressure (21.1+/-4.4 cm, mean+/-SD) and shorter survival (median 0.6 yr) than the other 27 patients (32.6+/-5.3 cm, 5.0 yr). The preoperative estimation of portal pressure-diverted portal flow curve slope anticipates the hepatic vascular response to portacaval anastomosis and identifies a group of patients in whom loss of portal blood flow results in a low residual intrahepatic venous pressure that is associated with early death and chronic encephalopathy.
Factors Impacting Entrepreneurial Intention: A Literature Review

Entrepreneurship has captured the attention of policymakers, educators and researchers in the last few decades. It has been regarded as a main driver for economic growth, development and employment generation in many countries worldwide. However, scholars have not agreed on the key factors that impact entrepreneurial intention. This study attempts, through an extensive literature review, to provide a holistic view and a more comprehensive understanding of the key factors that lead university undergraduate students to become entrepreneurs. A systematic literature review is conducted and several scientific articles and reports have been examined. The results of this study indicate that there are four main sets of factors: the personality-traits factors, contextual factors, motivational factors, and personal background factors. This research will serve as a base for future studies and will have valuable implications for policy makers and educators. Keywords—Entrepreneurship, Entrepreneurial Intention.
CoAP Option for Capability-Based Access Control for IoT-Applications

Access control is critical for many applications of the Internet of Things (IoT) since the owner of an IoT device (and application) may only permit one user to access a subset of the resources of the device. To provide access control for an IoT network, recent work adopted the capability-based access control (CBAC) model, which allows an IoT device to decide on the authorization by itself based on a capability token. However, the existing approaches based on CBAC directly attach the capability token at the end of CoAP when sending a request message. For the receiver, it is not easy to retrieve the capability token from the request message if the CoAP payload is present, because CoAP does not have a length field to indicate the size of its payload. To counter this problem, we propose a CoAP option, Cap-Token, to encapsulate a capability token when sending request messages. Because a CoAP option is independent from other CoAP fields, a receiver can get the capability token from the Cap-Token option of the request message without ambiguity. We also provide a compression mechanism to reduce the size of the Cap-Token option. Our evaluation shows that the compression mechanism can save the size of the option by 60%. Adding a compressed Cap-Token option to a request message increases the IP datagram size by 45 bytes, which is only 41% of the increase when directly attaching the capability token
Molecular Comparison of the Mitochondrial and Cytoplasmic hsp 70 of Trypanosoma cruzi, Trypanosoma brucei and Leishmania major

ABSTRACT. We compared the expression and localization of the mitochondrial and cytoplasmic hsp70 of the protozoans Trypanosoma cruzi, Trypanosoma brucei and Leishmania major. The mitochondrial protein is encoded by multiple mRNA in all species, while the cytoplasmic protein is encoded by a single mRNA. In all three species, the mitochondrial hsp70 is concentrated in the kinetoplast, a submitochondrial structure that houses the unusual DNA (kDNA) that characterizes this group of organisms, while the cytoplasmic protein is distributed throughout the cell. These results suggest that, in all kinetoplastid species, mt‐hsp70 has a specific function in kDNA biology, possibly in the processes of kDNA replication, RNA editing or kinetoplast structure.
RNA Secondary Structure Prediction

Details for predicting secondary structure of RNA sequences using free energy minimization are given. Protocols present the use of the RNAstructure computer program (for PCs) and the mfold server (for Unix platforms). The minimum free energy structure and a set of suboptimal structures with similar free energies are predicted. Prediction of high‐affinity oligonucleotide binding sites to a structured RNA target is also presented.
The Effect of Calcitriol on Patients with Postmenopausal Osteoporosis with Special Reference to Fracture Frequency

Malabsorption of calcium is a common finding in patients with postmenopausal osteoporosis (1, 2). In a number of studies serum 1,25 dihydroxyvitamin D levels were found to be significantly lower in osteoporotic patients, which could account for the calcium absorptive defect (3–6). Based on these findings, we studied the effects of synthetic calcitriol (Rocaltrol) in women with osteoporosis. We showed that calcitriol, 0.25 μg twice daily, improved and normalized the absorption of calcium in all patients and improved calcium balance (7). Urine hydroxyproline, which is a measure of bone resorption, decreased significantly after 2 years of treatment with Rocaltrol. Because of these preliminary findings, further clinical studies were carried out at two centers using a variable dose of Rocaltrol. In these studies we focused on the effectiveness of Rocaltrol in preventing vertebral fractures in patients with spinal osteoporosis. Methods The results from two centers have been analyzed both as separate groups and as one combined group. One study was performed at the Mayo Clinic (Protocol 861) and the other at Creighton University (Protocol 860). In both centers the studies performed were double blind and randomized, and compared the effect of placebo against Rocaltrol for a period of 1 year. At the end of 1 year all patients on placebo were crossed over to treatment with Rocaltrol and followed for 2 more years. Patients initially treated with Rocaltrol were followed for an additional 2 years, thus yielding treatment data extending to 3 years in a number of patients. In the study design, patients were given Rocaltrol at a starting dose of 0.25 μg twice daily, if hypercalcemia and hypercalciuria did not occur the dose then was increased to 0.75 μg or 1.0 μg daily at the discretion of the investigator.
Formal Knowledge Engineering Methods for Knowledge Discovery

This paper presents a framework for the integrated use of formal knowledge engineering methods and data mining based knowledge discovery methods. Knowledge is a key enterprise asset, and organizations are adopting both knowledge engineering and knowledge discovery paradigms for better knowledge management and enhanced decision support capability. Although there exists a useful interdependence between these endeavors, not much effort has been focused on using the full potential of one for the other. This paper presents a framework for the integrated use of established formal knowledge engineering methods and knowledge discovery processes with the ultimate intent of better managing the enterprise knowledge life cycle. It provides a brief overview of the knowledge discovery processes, and introduces a class of formal knowledge engineering methods and the perceived role of these methods in supporting the integration between the two worlds of knowledge discovery and knowledge engineering.
CFD Modeling of Boiling in a Microchannel Based On Phase-Field Method

The hydrodynamics and heat transfer characteristics of a vaporized elongated bubble in a rectangular microchannel have been simulated based on Cahn-Hilliard phase-field method. In the simulations, the initially nucleated bubble starts growing as it comes in contact with superheated water. The growing shape of the bubble compared well with the available experimental data in the literature. Keywords—Microchannel, boiling, Cahn-Hilliard method, Twophase flow, Simulation.
Combination therapy for gastrointestinal stromal tumors: evidence from recent clinical trials

Gastrointestinal stromal tumors (GIST) are neoplasms of mesenchymal origin arising from the GI tract. These tumors are characterized by activating mutations of the receptor tyrosine kinases, either KIT or PDGFRa, which are found in 85% of cases. Despite the use of imatinib in first-line and sunitinib in second-line treatment, patients with metastatic GIST still have a high risk of progression and death. To date, the median overall survival for metastatic disease is close to 5 years. Treatment with imatinib, an inhibitor of KIT and PDGFRa, results in clinical benefit, that is, objective responses or disease stabilization in approximately 85% of patients with unresectable or metastatic GISTs. However, metastatic GIST develop resistance to imatinib at a median time of 24 months, and sometimes more than 8 years after initiation of the treatment. In addition, as many as 15% of patients do not respond initially to imatinib; therefore, novel therapeutic options, new drugs or combination are needed. Genotypic ana.