Miracle-dz/UniFAR-FTUs huggingface dataset:
Mechanisms of Myofibril Assembly

The development and proliferation of undifferentiated cells into muscle is called myogenesis while the more specific process of myofibril assembly is called myofibrillogenesis. The assembly of myofibrils from their constituent proteins is acomplicated process and the mechanisms involved are just beginning to be understood at the cellular level. During differentiation of myoblasts, there is a dramatic shift in protein expression, resulting in the synthesis of muscle-specific proteins. These myofibrillar proteins subsequently associate into the highly organized supramolecular structure called the myofibril. The mechanisms by which the thin and thick filament components are aligned and interdigitated are poorly understood. Some of the mechanisms involved in the formation of thin and thick filaments reside in the domains on the constituent proteins. Both myosin and actin will polymerize in vitro to form filamentous structures, yet the resulting filaments have highly variable lengths in contrast to those found in the myofibril. Thus, there must be some cellular mechanism which dictates the organization and final filament lengths that are observed in the sarcomere. This mechanism likely involves a higher-level protein template or foundation upon which the nascent filaments form and subsequently interdigitate, giving rise to the myofibril. The ultrastructure of the mature myofibril and cartoons of the arrangements of its constituent contractile and structural proteins are shown in Figure 1. A few features of this diagram represent observation from more recent studies. These include the spanning of titin from the Z-line to the middle of the Aband (Furst et al., 1988); the binding of nebulin along the thin filament (Wang and Wright, 1988); capping of the actin filaments at the Z-line by the protein Cap Z (Casella et at., 1987); and the localization of zeugmatin at or near the Z-line (Maher et al., 1985). At right, we describe the processes involved in the assembly of this structure with emphasis on the mechanisms thought to be involved in this process. Other reviews on this subject can be found in Fischman (1986) and Epstein
Hs-CRP and TNF- alpha in response to a stepwise incremental bicycle test in adult obese men

To compare of circulating levels of as tumor necrosis factor-α (TNF-α) and C reactive protein (CRP) as proinflammation cytokines between obese and none obese men and also to evaluate its response to a stepwise incremental bicycle test in obese men, eighty sedentary adult obese men (30 ≤ BMI ≤ 36, 40 ± 5 aged) and twelve none-obese men matched for age participated in this study. Fasting blood samples were obtained of two groups in order to measuring serum CRP, TNF-α, insulin and glucose. Depending of the values of insulin and glucose insulin resistance index (HOMA2) was calculated. Blood samples were also repeated in obese group after exercise test in order to determine all variables responses to exercise. Statistical analysis was performed with the SPSS software version 15.0 using an independent paired t-test. At baseline, Serum TNF-α, CRP, insulin and glucose concentrations and insulin resistance were significantly higher in obese group than in normal weight subjects (p ˂ 0.05). Compared to pre-training, the CRP and TNF-α levels increased significantly (P<0.01) after acute exercise while glucose concentration decreased significantly in studied obese participants (p<0.05). No significant differences were found in insulin resistance by cycling exercise with compared to baseline (p = 0.154). This study suggests obesity is associated with systemic inflammation and a incremental cycle test have inflammatory properties regardless that is not related with glucose concentration. *Corresponding Author: Eizadi Mojtaba  izadimojtaba2006@yahoo.com Journal of Biodiversity and Environmental Sciences (JBES) ISSN: 2220-6663 (Print) 2222-3045 (Online) Vol. 1, No. 3, p. 35-43, 2011 http://www.innspub. net
A Robust, Distortion Minimization Fingerprinting Technique for Relational Database

— W ith the widespread popularity of internet, the use of digital data has increased tremendously. In this context, it is essential to protect the ownership of the data and to find the guilty user. In this paper, a fingerprinting scheme is proposed to provide protection for relational database (RDB), which basically focuses on challenges like 1.Minimum distortion in database. 2. Usability constraints non-violation.3. Robustness against collusion attack. 4. Should not violate the requirement of blind decoding. The proposed fingerprinting scheme focuses on all these requirements
Key Determinants and the Effects of Perceived Value on E-Commerce Repurchase Intention in Vietnam

The purpose of this paper is to explore how customers repurchase intention of e-commerce in Viet Nam which is considered as a potential country in developing this field. This paper focuses to the effects of perceived value on online repurchase intention of e-commerce in Viet Nam and what key determinants affect to the perceived value. To test the proposed hypotheses, the quantitative method is applied to collect the data. The partial least square (PLS) was used as a technique to analyze the data included the measurement as well as structural model. Data from this research collected from 261 Vietnamese online shoppers who have already purchased in E-commerce in Viet Nam. ___________________________________________________________________________
A Wireless Wearable Back Angle Measurement System for Sports and Therapeutic Applications

Back angle measurement in coronal plane provides a significant insight into the condition of spinal cord for certain physical conditions. This data would especially be useful for sports and therapeutic conditions, namely for modification of playing styles, ergonomic design, treatment of back pain and many more. Such data can also be used for injury predictions in case of repeated similar lower back movements. In this communication the authors implemented a wearable wireless system which can gather the necessary data from the candidate’s body which can be further used with data analytic techniques. The implemented system is based on a modular platform which uses plug and play hardware modules viz. micro-controller, accelerometer sensor, gyroscope and an RF module. A wireless node designed, which can use the sensor data to analyze lower back movement of subject’s body. A hub-module is connected to the laptop at remote site for wireless data acquisition of the meaningful signals. The implemented system shows improvement in experiment error which is an advantage over similar existing
Biodiesel Potentials and Lubricating Properties of Citrus sinensis Seed Oil

Potentials of Citrus sinensis seed oil were evaluated for its biodiesel and lubricating properties. The oil of C. sinensis seed was extracted using n-hexane and then transesterified using various methanol: oil ratios. The physicochemical properties of the oil and the resultant biodiesel, such as viscosity, acid value, iodine value, free fatty acid value, pour point, cloud point, smoke point, specific gravity and surface tension, were determined. The raw oil exhibited a low oxidative stability, while the biodiesel ratio with the highest methanol content had a biodiesel potential that could compete favourably with that of fossil diesel. The test for the burning efficiency of the respective biodiesel ratios indicated that the ratio with the lowest alcohol content had the best burning efficiency. This was evident from its relatively low flash point. The study concluded that the non-edible oil obtained from the seeds of C. sinensis could serve as a highly reliable substitute for the production of very good quality biodiesel fuels.
Analysis on Electromagnetic Radiation in Mobile Base Station in Mandalay Region

The paper presents the analysis on electromagnetic radiation in Mobile Base Station in Mandalay. The electromagnetic radiation effects are critical challenging issue in modern daily life of mobile users. The objective of this work is to investigate whether there is an excess of electromagnetic radiation which can potentially violate the public health safety. The target field is mainly focused on the location of country side and downtown area in Mandalay. The experimental studies for electromagnetic radiation in the specific areas could be confirmed and measured for the actual condition. The experimental studies have been carried out at 40 m, 60 m, 70 m and 90 m for measurement location for downtown site III in Mandalay Region. The outstanding observation for such kind of experimental works was very useful for measuring the radiation in mobile base station in Myanmar. The experimental measurement results have been analysed in this paper. Finally, the safe site from electromagnetic radiation effects could be recommended for people in Mandalay. The analyses confirm that the experimental works could be observed to recommend the usage of mobile devices safely. The confirmation of valuable analyses on electromagnetic radiation in mobile base station would be observed from that experimental works.
THERAPEUTIC POTENTIAL OF CUCURBITS AGAINST RADIATION INDUCED INFLAMMATION AND DAMAGE IN MICE GUT

Whole body or local irradiation to gut is known to induce significant damage to gut epithelium and crypt stem cells. A large population of microbes in the gut remains unaffected. We hypothesize that the modifications in diet and enteric microbial population may provide a non-toxic mechanism to counter radiation induced health deficit, especially in the gut and therefore investigated the effect of dietary cucurbits in this context. Radio-protective effects of Lagenaria (Ls), Cucurbita (Cp) and Luffa (Lc) were evaluated in mice for cytokines (in jejunum tissues) through ELISA and intestinal villi microscopically. Irradiation of mice increased pro-inflammatory biomarkers NAP-3, IFN-γ and IL-17 and decreased anti-inflammatory biomarkers IL-10, IL-4 and TGF-β. Post-irradiation treatment with cucurbit extract (Ls, Cp or Lc) decreased pro-inflammatory cytokines NAP-3, IFN-γ and IL-17 and increased anti-inflammatory cytokines IL-10, IL-4 and TGF-β in mice. Treatment with cucurbits restored structural integrity of villi in irradiated mice. Various antioxidants and anti-inflammatory molecules present in cucurbits, their positive effects on probiotics and host tissues and microbial fermentation of dietary fibers may mitigate radiation induced damage. The cucurbits, as non-toxic anti-inflammatory agents and nutrition enhancer can be helpful in irradiated and inflamed systems. INTRODUCTION: Whole body exposure to ionizing radiations results in production of reactive oxygen species, which initiate a series of signalling cascades and lead to the genesis of several proinflammatory responses in various tissues and systems leading HP and GI syndrome, depending on the dose received 1, 2 . Radiation induced inflammation in the gut is one of the major events during radiotherapy and radiation accidents. QUICK RESPONSE CODE DOI: 10.13040/IJPSR.0975-8232.9(2). 550-62 Article can be accessed online on: www.ijpsr. com DOI link: http://dx.doi. org/10.13040/IJPSR.0975-8232.9(2). 550-62 The gut mucosa, under normal conditions maintains a quiescent state against a diverse array of dietary antigens and luminal microbes. However exposure to ionizing radiation leads to gut inflammation and stem cell necrosis 3, 4 . The inflammatory manifestations of the gut are therapeutically managed in palliative and symptomatic manner through analgesic, anti-emetic and anti-diarrheal agents, though most of them induce adverse effects 5 . In view of this, the search for newer, less toxic and more effective anti-inflammatory agents becomes inevitable. In fact, a large number of agents of natural and synthetic origin have been attempted against gastro-intestinal (GI) inflammation 6 . The
Direction of Departure (DOD) and Direction of Arrival Estimation in Bistatic MIMO Radar Using Covariance Recovery of Sparse Targets

This letter propose a new method based on covariance sparse target recovery for Direction of Departure (DOD) and Direction of Arrival (DOA) in bistatic multi -input multi-output radar. The letter use this property that the number of target in the space is low. In this paper we recover the power of incident signal as a diagonal matrix which its diagonal element are corresponding to the impinging signals. We show that our method doesn’t need the number of sources and also it is independent from the coherency between the signals. Simulation results demonstrate the effectiveness of our algorithm compared with other methods. KeywordsMIMO, Radar, DOA and DOD ,Sparse.
The Impact of Nutrition on the Autonomic Nervous System

Autonomic imbalance measured by 24 hour HRV (heart rate variability) analysis is described for overweight children as well as for patients with anorexia nervosa. Autonomic imbalance is a predictor of possible metabolic syndrome, cardiovascular disease and impaired neurodevelopment. In our cross-sectional study we compared HRV parameters for a healthy control group and constitutional thinness with patients with anorexia nervosa and overweight children. We had found that, children with anorexia nervosa had had significantly lower heart rates at night whilst in overweight children significantly higher heart rates. Concomitant anorexia nervosa patients children with constitutional thinness and the same body mass index (BMI) had a significantly higher SDNN (standard deviation of all RR-intervals) while overweight children had a significantly lower SDNN. Within all groups we had found a strong and significant correlation between SDNN and heart rate at night. The obesity education program KIDS and the in hospital refeeding in anorexia nervosa patients significantly improved heart rate variability. Chi square test show a highly significant interrelationship between changes in BMI and changes in 24 hour heart rate. Micro nutrition and the role of omega-3-fatty supplementation was measured and discussed. Our data were compared with data of undernourished and stunted children from the literature. We concluded that not current BMI but rather metabolic rate predominantly determines intrinsic heart rate. We propose a comprehensive model to explain the impact of nutrition on the autonomic nervous system and discuss the therapeutic consequences. *Corresponding author: Prof. Reiner Buchhorn, Klinik für Kinderund Jugendmedizin, Caritas Krankenhaus Bad Mergentheim, Uhlandstr. 7, 97980 Bad Mergentheim, Germany, Tel: 07931-582301; Fax: 07931-582390; E-mail: reiner.buchhorn@ckbm.de Received Date: May 23, 2016 Accepted Date: June 09, 2016 Published Date: June 13, 2016
A New PV/Fuel Cell Based Bidirectional Converter for Microgrid Applications

The penetration of renewable energy in modern power system, microgrid has become a popular application worldwide. In this paper bidirectional converters for AC and DC hybrid microgrid application are proposed as an efficient interface. To reach the goal of bidirectional power conversion, both rectifier and inverter modes are analyzed. In order to achieve high performance operation and single-phase bi-directional inverter with dc-bus voltage regulation and power compensation in dc-microgrid applications. This concept proposes a control design methodology for a multi functional single-phase bidirectional PWM converter in renewable energy systems. There is a generic current loop for different modes of operation to ease the transition between different modes, including stand-alone inverter mode, grid-tied inverter mode, ac voltage regulation is of importance because of the sensitive loads In dc-microgrid applications, a power distribution system requires a bi-directional inverter to control the power flow between dc bus and ac grid, and to regulate the dc bus to a certain range of voltages, in which dc load may change abruptly. This will result in high dc-bus voltage variations; the bi-directional inverter can shift its current commands according to the specified power factor at ac grid side. Parallel-connected bidirectional converters for AC and DC hybrid microgrid application are proposed as an efficient interface. To reach the goal of bidirectional power conversion, both rectifier and inverter modes are analyzed. The Simulation results are carried out by Matlab/Simulink to verify the performance of the proposed method.
The rising role of natural killer cells in patients with malignant hematological disorders and in recipients of hematopoietic stem cell transplantation

Natural killer (NK) cells, the third population of lymphoid cells, comprise 5%-25% of peripheral blood (PB) lymphocytes and represent the irst line of defense against infections and tumors [1-7]. They can be derived from: bone marrow, PB, cryopreserved umbilical cord blood (UCB), human embryonic stem cells (hESCs), induced pluripotent stem cells (iPSCs), and various cell lines such as NK-92 and KHYG-1 [1]. NK cells; which have been divided into cytotoxic, tolerant, and regulatory subsets; are classi ied into: (1) naïve CD56 bright CD 16 dim CD 3 dim cells, (2) mature CD56 dim CD16 bright CD3 dim cells, and (3) lymphoid tissue-resident CD69+/CXCR6+ NK cells [1,2,8-11]. Although NK cells have been traditionally considered as part of the innate immune system, they have recently been shown to exhibit many of the features associated with adaptive immunity [8,12]. The functions of NK cells which are in luenced by several cytokines include: elimination of infected cells, destruction of cancer cells, reducing the incidence of graft versus host disease (GVHD) following hematopoietic stem cell transplantation (HSCT), and regulation of pregnancy outcome [10,11,13]. NK cell function is inely tuned by activating and inhibitory receptors that recognize both foreign and self-antigens expressed by NK cell-susceptible targets [7,14]. Activated NK cells interact with dendritic cells (DCs) and mesenchymal stem cells (MSCs) and the complicated crosstalks between NK cells, MSCs, and DCs may alter the functions of any of the 3 cell types [15-27].
COMPARATIVE ASSESSMENT OF ZINC SULPHATE AND ESSENTIALE FORTE® IN MANAGING BIOCHEMICAL ALTERATIONS OF CARBON TETRACHLORIDE –INDUCED HEPATOTOXICITY ON ADULT WISTAR RATS

INTRODUCTION Most routine tests reflect liver damage the tests of function are those which reflect synthetic capacity for instance albumin and prothrombin time, liver function tests may be grossly deranged when function is normal and may be normal when function is grossly deranged for it has enormous functional reserves, such that early liver impairment is clinically masked and the progression of the deranged liver function makes the condition life threatening( Cotran et al.,1999). Morphologically, liver responds to injurious events in 5 different ways, irrespective of the cause viz; Degeneration and intracellular accumulation, Necrosis and Apoptosis, Inflammation, Regeneration, Fibrosis (Cotran et al.,1999).
A Superior Advance for Explore Results Using Web Mining

— An increasing number of databases have become web accessible through HTML form-based search interfaces. The data units returned from the underlying database are usually encoded into the result pages dynamically for human browsing. In this project proposed automatic annotation results for both image and page labels from aligned groups of images and pages. This aim is to improve user satisfaction by returning images that have a higher probability to be accepted by the user. The assumption is that the users search for images by issuing queries, each query being an ordered set of keywords and then improve automatic data alignment problem. Accurate alignment is critical to achieving holistic and accurate annotation. To use the wrapper to annotate a new result page, for each data unit in an SRR, the annotation rules are applied on it one by one based on the order they appear in the wrapper. If this data unit has the same prefix and suffix as specified in the rule, the rule is matched and the unit is labeled with the given label in the rule. Because of the supervised training and learning process, these systems can usually achieve high extraction accuracy. The proposed system is dynamically trained by the queries of the same users that will be served by the system.
Immobilized Biocatalyst for Production of Red Table Wines

A method of obtaining high-yielding immobilized biocatalyst based on cells of mycelial fungus Aspergillus awamori (a new strain of F-RKM 0719) has been technologically developed and tested, which is able to secrete extracellular pectinases for long time during cultivation. The carrier of immobilized cells was cryogel of polyvinyl alcohol, which is a high strength macroporous viscoelastic gel material with good biocompatibility and stability in biological environments. Thanks to these properties, this carrier allows easy diffusion of components of the nutrient medium and metabolic products. An immobilized biocatalyst is obtained by gelation of polyvinyl alcohol with simultaneous immobilization of cells of A. awamori F-RKM 0719. To obtain the maximum enzymatic activity of immobilized biocatalyst, concentration of the carrier and concentration of the cells were found experimentally. The level of total accumulated pectolitic activity of the developed immobilized biocatalyst exceeds 3.5 times the level of strain A. awamori F-RKM 0719 obtained in multi-stage breeding and used without immobilization. Thus, there is no need to isolate pectolitic enzymes from the cultural fluid, which significantly reduces the economic expenditures, and thus it is possible to reuse many times the immobilized biocatalyst that produces, outside the cell, the required balanced complex of pectolitic enzyme preparations in the process of technological operations in wine production.
Design of Neural Architecture Using WTA for Image Segmentation in 0.35μmTechnology Using Analog VLSI

Artificial neural network are attempts to mimic, at least partially, the structure and function of brains and nervous systems. The human brain contains billion of biological neurons whose manner of interconnection allow us the reason, memorize and compute. Advances in VLSI technology and demand for intelligent machines have created strong resurgence of interest in emulating neural system for real time applications. Such an artificial neural network can be built with help of simple analog components like MOSFET circuits and basic circuits with help of operational amplifier.WTA circuits are used to identify active output from numbers of inputs so using this we can use neural architecture for image segmentation especially for X-Ray image. This paper gives information about neuron behaviour and how it takes intelligent decision how it can segment the especially medical images
The efficacy of the Internet and Social Media as Medical Marketing Tools

The role and efficacy of online marketing in healthcare remains underexplored. The present study, focusing on one medical specialty, investigates the perceived role of the Internet and social media as marketing tools from the perspectives of both healthcare providers and patients. It assesses their role as communication and customer acquisition channels and identifies differences in perceptions between providers and patients. The findings suggest that the role of the Internet and social media as patient acquisition channels is limited but presence of healthcare providers in these channels is considered as important for reassuring customers. The results indicate that the online presence of healthcare providers in a web site is considered as a given fact by patients (a hygienic factor in Herzberg's terminology) while the presence in social media has a reinforcing impact (a motivating factor in Herzberg’s terminology) with important effect on trust and long-term relationships.