Miracle-dz/UniFAR-FTUs huggingface dataset:
Aplicación de auriculoterapia para el tratamiento de cefalea: puntos álgicos más frecuentes

Objective: To analyze the effect of auricular therapy with mustard seeds on the complaints of headache and migraine of volunteers using a semi-structured protocol. Methods: Retrospective descriptive documentary study, of quantitative character, realized between April and June 2019. In this study, 60 volunteers were evaluated, aged between 16 and 58 years. Being selected the volunteers who presented complaints of headache and / or migraine and among those who performed three or more visits. Results: After the analysis of the sample, the prevalence was 22 (8 volunteers), 24 (4 volunteers) and 25 (4 volunteers) and from the academic community, with 32 volunteers. Almost all volunteers reported reduced headache / migraine symptom and only one presented increased pain symptoms. The ear points prevalent in this study were: Anxiety, Cervical Vertebrae and Neurasthenia. Conclusion: The auriculoterapia with mustard seeds obtained positive effects in the reduction of the cephalic pain of the volunteers, and enabled an integral understanding of the individual through the verification of the reactive points.
Experimental investigation of interactions between the perennial red alga Gelidium pusillum and barnacles on a New South Wales rocky shore

On rocky shores in New South Wales, the perennial red alga Gelidiurn pusillurn (Stackhouse) Le Jolis occurs only within a midshore barnacle zone. This alga was rarely found to recruit from propagules but instead persisted as patches within the zone. Although barnacles did not influence the growth rate of G. pusillurn they were crucial to the survival of the patches. G. pusillurn that had overgrown the barnacle Tesseropora rosea Krauss stabilized the dead tests, thus postponing the reallocation of bare space on the shore otherwise available for settlement by other organisms. Survival of juvenile herbivorous molluscs sheltering in tests was also affected by the abundance of an algal covering over the barnacle shells. Results suggest that many interactions are taking place and that some of these can have opposite effects depending upon the abundance of component species.
Role of the Connectivity of Secondary Structure Segments in the Folding of α1-Antitrypsin

Abstract The native form of serpins (serine protease inhibitors) is metastable, which is critical to their biological functions. Spontaneous conversion from the native form of serpins into a more stable conformation, called the “latent” form, is restricted. To examine whether the connectivity of strand 1 of β-sheet C to the hydrophobic core is critical to the serpin's preferential folding to the metastable native conformation, we designed a circularly-permuted mutant of α 1 -antitrypsin, the prototype serpin, in which strand 1C is disconnected from the hydrophobic core. Conformation of the circular permutant was similar to that of the latent form, as revealed by equilibrium unfolding, limited proteolysis, and spectroscopic properties. Our results support the notion that rapid folding of the hydrophobic core with concomitant incorporation of strand 1C into β-sheet C traps the serpin molecule into its native metastable conformation.
Dipole vortices in the Great Australian Bight

Shipboard measurements from late 2006 made by the Danish Galathea 3 Expedition and satellite sea surface temperature images revealed a chain of cool and warm ‘mushroom’ dipole vortices that mixed warm, salty, oxygen-poor waters on and near the continental shelf of the Great Australian Bight (GAB) with cooler, fresher, oxygen-rich waters offshore. The alternating ‘jets’ flowing into the mushrooms were directed mainly northwards and southwards and differed in temperature by only 1.5°C; however, the salinity difference was as much as 0.5, and therefore quite large. The GAB waters were slightly denser than the cooler offshore waters. The field of dipoles evolved and distorted, but appeared to drift westwards at 5km day–1 over two weeks, and one new mushroom carried GAB water southwards at 7km day–1. Other features encountered between Cape Leeuwin and Tasmania included the Leeuwin Current, the South Australian Current, the Flinders Current and the waters of Bass Strait.
Isolation of six microsatellite markers from the pea aphid, Acyrthosiphon pisum (Homoptera, Aphididae)

Using the magnetic particles method, we isolated six polymorphic microsatellite loci from the pea aphid, Acyrthosiphon pisum (Harris), which feeds on a wide range of legume species. The isolated loci were polymorphic, with three to six alleles in 40 aphids. Expected heterozygosities ranged from 0.12 to 0.65. These loci can be used to quantify clonal diversity and compare genetic population structure between sexual and asexual populations.
PENGARUH SENAM REMATIK TERHADAP NYERI SENDI PADA LANSIA DI PUSKESMAS PADANG BULAN

The body's degenerative processes that occur with age will increase the risk of joint pain due to knee osteoarthritis, especially in the elderly. Joint pain experienced will reduce the physical activity of the elderly and have an impact on decreasing the scope of joint motion. One of the non-pharmacological measures that can be used to reduce the scale of joint pain is rheumatism. Active and mild movements without using a load in rheumatic exercises trigger beta-endorphin release, the body's natural neuromudulator that can inhibit the release of pain impulses so that the elderly joint pain scale is reduced. This study aims to look at the effect of rheumatic exercises on joint pain in the elderly at the Padang Bulan Community Health Center. The study design used was a quasi one group pre and post test without control experiment with a population of all joint pain sufferers in the elderly and each sample of 32 respondents in the intervention group, taken by purposive sampling. Analysis of the data used is Paired T-Test. The pain scale in this study was measured using the Pain Numeric Scale. The results of this study indicate that there are significant differences in joint pain before and after administration of rheumatic exercises in the intervention group: P Value = 0.000 (p <0.05). Conclusions rheumatic exercises provide a beneficial effect on decreasing joint pain in the elderly so it is recommended for further researchers to conduct research on the effects of rheumatic exercises on other factors that can affect joint pain
Yellow eye, a new pigment mutation in Ephestia kuehniella Zeller (Lepidoptera: Pyralidae).

Marec, F. and Shvedov, A. N. 1990. Yellow eye, a new pigment mutation in Ephestia kuehniella Zeller (Lepidoptera: Pyralidae). —Hereditas 113: 97–100. Lund, Sweden. ISSN 0018–0661. Received April 10, 1990. Accepted June 19, 1990 A new eye-colour mutant, yellow eye (y), is described for Ephestia kuehniella. This mutation is inherited as an utosomal recessive to wild-type. Studies on the interaction between y and two other autosomal recessive mutations, wa (white eye) and a (red eye), revealed that y is non-allelic with both these mutations. It was found that wa is phenotypically epistatic over y, and y is epistatic over a. The y is not linked to wa or a genes. The yellow colour of eyes of y mutants is probably due to some pteridine pigments.
Influence of Feed Particle Density on Paniculate Passage from Rumen of Holstein Cow

Abstract The response of rumen turnover rate to increasing alfalfa fiber density or chromium concentration was evaluated. Alfalfa fiber density was elevated by mordanting with increasing chromium concentrations. As chromium concentration of the mordanting solution was raised, there was a concomitant increase of chromium content and density of the resultant alfalfa fiber. Two Holstein cows were fed for ad libitum consumption equal portions of a total mixed ration three times a day. Cows were fed a pulse dose of marker, and fecal grab samples were collected at scheduled intervals for 5 days. Chromium analysis was on the undigested cell wall. By linear regression analysis the slope was fit for the declining phase of the marker excretion curve. Rumen turnover rates (h −1 ) and cell wall densities (g/ml) were: . 0107, 1.126; . 0072, 1.165; . 0191, 1.242; . 0228, 1.396; and . 0194, 1.703 for alfalfa cell wall mordanted with 2, 4, 8, 16, or 32% chromium concentrations. Particle density and chromium concentration may be important factors affecting rate of particle turnover in the rumen.
Tools and Techniques for Energy-Efficient Mobile Application Development

Driven by their convenience and ubiquitousness, smartphones have been widely adopted over the past ten years. As a consequence, mobile apps have rapidly become indispensable to perform everyday tasks. Users rely on mobile apps to accomplish tasks such as calling a taxi, renting a car, paying at grocery stores, ordering food, and so on. Nowadays, being unable to operate with a smartphone device, may imply being unable to carry out important tasks. This is the case when our smartphone runs out of battery. Thus, it is essential to ensure that mobile apps are energy-efficient. However, as we demonstrate in this thesis, developing energy-efficient code is not as trivial as one could imagine. Previous research has tackled this issue by proposing techniques and tools to design energy-efficient mobile apps (e.g., studying anti-patterns) and reliably assess energy improvements (e.g., software-based energy estimators). In this thesis, we extend this research problem by studying how developers address energy efficiency, pinpointing potential issues entailed by building energy-efficient code, and proposing new techniques and practices to help developers address energy-related requirements. We start by compiling the current state-of-the-art methodologies used to measure the energy consumption of mobile apps. Moreover, we study the limitations of these methodologies. In particular, we measure the energy overhead entailed by using User Interface testing frameworks during measurements. We show that popular frameworks such as Calabash and AndroidViewClient should be avoided when measuring energy consumption. Following, we collect code smells from other non-functional requirements (in particular, performance) and explore their aptitude to improve energy efficiency. We find five performance-based code smells that effectively reduce energy consumption when fixed. Moreover, we study solutions typically applied to real-world energy efficiency issues. We collect and document a catalog of 22 energy patterns by inspecting energy-oriented changes in 1027 Android and 756 iOS apps. As a side contribution, we compare how Android and iOS developers address the energy efficiency of their apps.
Newer Developments in Arsenic Toxicity

There have been a number of new and exciting advances in the understanding of arsenic toxicity. Organic trivalent arsenicals have been the drug of choice in the treatment of African trypanosomes, the cause of sleeping sickness. In the past, various mechanisms have been proposed for their mode of action in the treatment of this parasitic disease. It now appears that these arsenicals form an adduct with N 1,-N8(glutathionyl)spermidine which inhibits trypanothione disulfide reductase. This enzyme in conjunction with a nonenzymatic reaction is responsible for the maintenance of the required intracellular levels of GSH and perhaps other thiols in African trypanosomes. The primary targets of As3+ in mammalian systems are pyruvate dehydrogenase, thiolase, and glutathione reductase. Even though it appears that pyruvate dehydrogenase is the most sensitive target, the net result of these inhibitions is a decreased gluconeogenesis that should be taken into account when treating arsenic poisoning. Although these advances have been made in the understanding of arsenic toxicity, virtually no progress has been made in understanding the biochemical mechanism of action of arsine, probably the deadliest of all arsenic compounds. This lack of progress is disappointing as well as worrisome since arsine is one of the important starting materials in the newer high tech industries. There have been, however, advances made in the treatment of arsenic toxicity. Meso-2,3-dimercaptosuccinic acid (DMSA) and 2,3-dimercaptopropane-l-sulfonic acid are orally effective, dithiol chelating agents useful for treating arsenic poisoning. DMSA is an orphan drug for which a New Drug Application has been filed.
Exploring Changes in Event-Related Potentials After a Feasibility Trial of Inhibitory Training for Bulimia Nervosa and Binge Eating Disorder

In a feasibility trial comparing two forms of combined inhibitory control training and goal planning (i.e., food-specific and general) among patients with bulimia nervosa (BN) and binge eating disorder (BED), we found evidence of symptomatic benefit, with stronger effects among participants receiving a food-specific intervention. The aim of the present study was to examine changes in behavioral outcomes and event-related potentials (ERPs; N2 and P3 amplitudes) from baseline to post-intervention that might suggest the mechanisms underpinning these effects. Fifty-five participants completed go/no-go tasks during two electroencephalography (EEG) sessions, at baseline and post-intervention. The go/no-go task included “go” cues to low energy-dense foods and non-foods, and “no-go” cues to high energy-dense foods and non-foods. Datasets with poor signal quality and/or outliers were excluded, leaving 48 participants (N = 24 BN; N = 24 BED) in the analyses. Participants allocated to the food-specific, compared to the general intervention group, showed significantly greater reductions in reaction time to low energy-dense foods, compared to non-foods, by post-intervention. Commission errors significantly increased from baseline to post-intervention, regardless of stimulus type (food vs. non-food) and intervention group (food-specific vs. general). There were no significant changes in omission errors. P3 amplitudes to “no-go” cues marginally, but non-significantly, decreased by post-intervention, but there was no significant interaction with stimulus type (high energy-dense food vs. non-food) or intervention group (food-specific vs. general). There were no significant changes in N2 amplitudes to “no-go” cues, N2 amplitudes to “go” cues, or P3 amplitudes to “go” cues from baseline to post-intervention. Training effects were only marginally captured by these event-related potentials. We discuss limitations to the task paradigm, including its two-choice nature, ease of completion, and validity, and give recommendations for future research exploring ERPs using inhibitory control paradigms.
PGR5/PGRL1 and NDH Mediate Far-Red Light-Induced Photoprotection in Response to Chilling Stress in Tomato

Plants experience low ambient temperature and low red to far-red ratios (L-R/FR) of light due to vegetative shading and longer twilight durations in cool seasons. Low temperature induce photoinhibition through inactivation of the photosynthetic apparatus, however, the role of light quality on photoprotection during cold stress remains poorly understood. Here, we report that L-R/FR significantly prevents the overreduction of the entire intersystem electron transfer chain and the limitation of photosystem I (PSI) acceptor side, eventually alleviating the cold-induced photoinhibition. During cold stress, L-R/FR activated cyclic electron flow (CEF), enhanced protonation of PSII subunit S (PsbS) and de-epoxidation state of the xanthophyll cycle, and promoted energy-dependent quenching (qE) component of non-photochemical quenching (NPQ), enzyme activity of Foyer-Halliwell-Asada cycle and D1 proteins accumulation. However, L-R/FR –induced photoprotection pathways were compromised in tomato PROTON GRADIENT REGULATION5 (PGR5) and PGR5-LIKE PHOTOSYNTHETIC PHENOTYPE1A (PGRL1A) co-silenced plants and NADH DEHYDROGENASE-LIKE COMPLEX M (NDHM) -silenced plants during cold stress. Our results demonstrate that both PGR5/PGRL1- and NDH-dependent CEF mediate L-R/FR –induced cold tolerance by enhancing the thermal dissipation and the repair of photodamaged PSII, thereby mitigating the overreduction of electron carriers and the accumulation of reactive oxygen species. The study indicates that there is an anterograde link between photoreception and photoprotection in tomato plants during cold stress.
Effects of Antimony on Reactive Oxygen and Nitrogen Species (ROS and RNS) and Antioxidant Mechanisms in Tomato Plants

This research studies the effects that Sb toxicity (0.0, 0.5, and 1.0 mM) has on the growth, reactive oxygen and nitrogen species, and antioxidant systems in tomato plants. Sb is accumulated preferentially in the roots, with little capacity for its translocation to the leaves where the concentration is much lower. The growth of the seedlings is reduced, with alteration in the content in other nutrients. There is a decrease in the content of Fe, Mg, and Mn, while Cu and Zn increase. The contents in chlorophyll a and b decrease, as does the photosynthetic efficiency. On the contrary the carotenoids increase, indicating a possible action as antioxidants and protectors against Sb. The phenolic compounds do not change, and seem not to be involved in the defense response of the tomato against the stress by Sb. The water content of the leaves decreases while that of proline increases in response to the Sb toxicity. Fluorescence microscopy images and spectrofluorometric detection showed increases in the production of O2. –, H2O2, NO, and ONOO–, but not of nitrosothiols. The Sb toxicity induces changes in the SOD, POX, APX, and GR antioxidant activities, which show a clear activation in the roots. In leaves, only the SOD and APX increase. The DHAR activity is inhibited in roots but undergoes no changes in the leaves, as is also the case for the POX and GR activities. Ascorbate increases while GSH decreases in the roots. The total AsA + DHA content increases in the roots, but the total GSH + GSSG content decreases, while neither is altered in the leaves. Under Sb toxicity increases the expression of the SOD, APX, and GR genes, while the expression of GST decreases dramatically in roots but increases in leaves. In addition, an alteration is observed in the pattern of the growth of the cells in the elongation zone, with smaller and disorganized cells. All these effects appear to be related to the ability of the Sb to form complexes with thiol groups, including GSH, altering both redox homeostasis and the levels of auxin in the roots and the quiescent center.
Taste Detection Thresholds in Relation to Salivary and Serum Zinc in Patients on Simvastatin Treatment

Background: Hyperlipidemia is an elevated fat (lipids), mostly cholesterol and triglycerides, in the blood. These lipids usually bind to proteins to remain circulated so-called lipoprotein. Aims of the study: To determine taste detection threshold and estimate the trace elements (zinc) in serum and saliva of those patients and compare all of these with healthy control subjects. Methods: Eighty subjects were incorporated in this study, thy were divided into two groups: forty patients on simvastatin treatment age between (35-60) years, and forty healthy control of age range between (35-60) years. Saliva was collected by non-stimulated technique within 10 minutes. Serum was obtained from each subject. Zinc was estimated in serum and saliva by flame atomic absorption assay. Taste detection threshold was estimated by using 15 different concentrations of the four basic tastes solutions, the test use sip and spit with deionized water as mouth wash interval. Diabetics, thyroid and parathyroid disease, autoimmune disease, chemotherapy, smoking, alcoholics, neoplastic diseases were excluded. Results: The study showed that the taste detection threshold of sour and bitter were highly significantly higher in those patients than that in control subjects, sweet detection threshold were significantly high in patient on simvastatin. The salt detection threshold showed no significant differences between study groups. Salivary flow rate was significantly decreased in patients on simvastatin treatment than that in control subjects. Salivary and serum zinc were highly significantly decreased in control subjects than those in patients. There was highly significantly positive linear correlation between salivary flow rate and the mean of detection threshold of sweetness and sourness of both study groups, and highly significantly negative linear correlation with the mean of detection threshold of saltiness and bitterness in both study groups.
Male Visitors May Decrease Modularity in Flower–Visitor Networks

An ecological community network generally has a clustering structure formed by evolutionary and ecological processes. Because females and males of a single visitor species often differ in their evolutionary and ecological relationship with flowering plants, visitor sex should affect the clustering structure of flower–visitor networks. Two related metrics are used to evaluate clustering structures: compartmentation and modularity. Compartmentation refers to the number of clearly separate subgroups, whereas modularity describes subgroups according to their number of aggregating links. Thus, compartmentation is a measure of network fragmentation and modularity is a measure of network heterogeneity. Because male visitors tend to give priority to search for mates, we hypothesized that male visitors increased compartmentation and decreased modularity compared with female visitors. By using museum specimens of flower–visitor insects together with the plant species that they were visiting, recorded at the time of collection, we constructed 11 networks for each research site and collection year, separated each into male and female subnetworks, and then compared the two metrics between them. Results showed that compartmentation was not different between them, while male subnetworks had lower modularity than female subnetworks, and strengthened modularity of species networks together with female subnetworks. These structural characteristics of male subnetworks likely reflect less choosy and less mutualistic visits of males compared with females. This might imply that the role of male visitors in maintaining flower diversity has been overlooked.
Redefinition of Holosticha Wrzesniowski, 1877 (Ciliophora, Hypotricha)

A revision of the urostylid hypotrichs showed that at present Holosticha is characterized by an unspecified combination of plesiomorphies. Thus more than 100 species have been originally described in this genus, and about 49 species are currently recognised. However, a detailed comparison of the descriptions showed that Holosticha comprises only 7 species unified by a highly characteristic combination of apomorphies (e.g. anterior end of left marginal row curved rightwards, adoral zone bipartite, buccal cirrus distinctly ahead of paroral) and plesiomorphies. The other species at present included in Holosticha are assigned to Anteholosticha nov. gen. (29 species), Caudiholosticha nov. gen. (10 species), and Biholosticha nov. gen. (2 species).