Miracle-dz/UniFAR-FTUs huggingface dataset:
Tratamiento de aguas residuales de la industria del café soluble vía Electrocoagulación - Oxidación Anódica. Selección de los electrodos

The industry of soluble coffee generates wastewater containing complex and hard to degrade mixtures of different substances. Their mineralization is not completely effective through conventional treatment methods. In this work, as a treatment alternative, a sequential Electrocoagulation-Anodic Oxidation (EC-AO) process is studied. The effect of electrode material (v.g., two different anodes (graphite and Boron-Doped Diamond (BDD)) and six different cathodes (stainless steel, titanium, iron, aluminum, graphite and BDD)) and of support electrolyte (NaCl or Na2SO4) on degradation performance of AO, in the terms of color and chemical oxygen demand (COD) reduction, as well as Total Suspended Solids (TSS) formation and pH, were experimentally tested. The obtained results were compared with the most recent Colombian environmental regulation. Additionally, for each case, a comprehensive operational costs analysis was performed. All the above information allowed to select two electrode systems as the most promising for the AO step: BDD-stainless steel + Na2SO4: very efficient but expensive (reduction of COD = 75% and 12 USD/ m3) and graphite-stainless steel + NaCl: less efficient and more economic one (reduction of COD = 67% and 7 USD/m3).
Effects of Brief Mindfulness Meditation on Pre-service Teachers’ Attitudes towards Including Students with Autism: The Role of Basic Psychological Need Satisfaction

ABSTRACT Enhancing teachers’ attitudes towards including students with autism spectrum disorder (ASD) are crucial for successful inclusive education. The current study, guided by self-determination theory, examined the effectiveness of mindfulness meditation on teachers’ attitudes towards including students with ASD. Pre-service teachers (n = 65) were randomly assigned to the experimental or the control group. The results showed that the mindfulness meditation did not improve pre-service teachers’ attitudes but their basic psychological needs satisfaction. In addition, mindfulness had an indirect effect on attitudes through needs satisfaction. These findings could be used for improving teaching preparation for inclusive education.
Resistance modulation of multilayer graphene controlled by the gate electric field

A simple and effective top gate fabrication was realized to construct a dual-gate structure on graphene. In addition to the SiO2/highly doped Si bottom gate, an aluminum layer was directly deposited on the graphene, followed by natural oxidation in the atmosphere, to form the top gate and dielectric layer underneath. Electric field modulation between the top and bottom gates was investigated in multilayer graphene (MLG) with different thicknesses, which enabled us to estimate the screening effect in the MLG. A thickness-dependent charge-neutrality-resistance peak shift was observed and clarified in terms of the inter-layer screening length to the electric field in the dual-gate structure. A screening length of 1.2 nm, corresponding to the thickness of three- or four-layer graphene, was experimentally estimated.
Cancer stem cell markers in lung adenocarcinoma

In solid tumors, cancer stem cells (CSCs) are defined as cells that have the ability to perpetuate themselves through self-renewal and to generate mature cells of a particular tissue through differentiation [1]. The CSCs hypothesis suggests that there is a small subset of cancer cells that are responsible for tumor initiation and growth, possessing properties such as indefinite self-renewal, slow replication, intrinsic resistance to chemotherapy and radiotherapy, and an ability to give rise to differentiated progeny. This suggests that CSCs resistant to these treatments are involved in cancer recurrence and metastasis. Therefore, there is an urgent need to identify new therapeutic drug targets for successful treatment. Lung cancer is the most common cancer worldwide with a 5-year survival rate of < 15%, the reason seems to be a lack of useful therapeutic targets [2]. As previously reported by Miyata et al. in our group, we reviewed ALDH1 and CD133 [3]. In addition, we investigated CD44standard (CD44st) and CD44variant6 (CD44v6) as CSC markers. ALDH1 proteins (mainly ALDH1A1, ALDH1A2 and ALDH1A3), which are primarily localized in the cytosol of cells from various tissues, include enzymes able to oxidize retinol and aliphatic aldehydes [4]. ALDH enzyme activity has also emerged as a promising marker of CSCs, and indeed as normal stem cells. In addition to being a putative stem-cell marker, ALDH activity is also known to be involved in drug resistance. In order to assess CSC markers in lung cancer specimens, a paraffin-embedded section is prepared, and histological diagnosis is performed by HE staining. The IHC staining is also performed by the LSAB method using the ALDH1A1 monoclonal antibody. The results were semi-quantitatively graded based on the percentage of cells stained and the intensity of staining. Briefly, the staining intensity was rated as weak (1+), moderate (2+), or strong (3+) and multiplied by the percentage of positive cells. ALDH1A1 score = (% of cells of intensity 1×1) + (% of cells of intensity 2×2) + (% of cells of intensity 3×3). The total scores were categorized as follows: 0-100 = Grade 1, 101-200 = Grade 2, 201-300 = Grade 3. Grade 2 or 3 tumors were considered positive for ALDH1A1 [4]. CD133 antigen, also called prominin 1 (PROM1), is a 120 kDa five-transmembrane glycoprotein. The function is currently unknown but it is expressed on the cell surface in many malignancies [4]. There is also considerable evidence here suggesting that CD133 expression in a subpopulation of lung cancer cells also identifies CSCs. The IHC staining of CD133 was performed on 5 micrometer (μm) paraffin sections using monoclonal antibodies. The CD133 expression score was defined as the percentage of cells showing strong expression levels in membrane sections of tumor
Limiting Laws and Counterion Condensation in Polyelectrolyte Solutions I. Colligative Properties

Formulas are derived for the osmotic coefficient, the Donnan salt‐exclusion factor, and the mobile‐ion activity coefficients in a polyelectrolyte solution with or without added sample salt. The formulas, which contain no adjustable parameters, are based on the (theoretical) observation by several workers that counterions will “condense” on the polyion until the charge density on the polyion is reduced below a certain critical value. The uncondensed mobile ions are treated in the Debye–Huckel approximation. In a restricted sense, the formulas are “limiting laws,” and this aspect is discussed at length. Detailed comparison with experimental data in the literature is given; agreement of the theory with experiment is usually found to be quantitative.
PATENTARY MAPPING, IN THE ORBIT INTELLIGENCE BASE, ON FERTILIZERS IN A BRAZILIAN SCENARIO

O crescimento da producao agricola no Brasil durante o periodo de 1950 a 1980 promoveu uma crescente diretamente ligada a producao e consumo de fertilizantes, com alavancagens que chegaram a triplicar a producao em dados periodos, fato que acarretou para uma procura e aumento da capacidade inovativa deste segmento de mercado. Com a finalidade de avaliar o momento de inovacao, suas tecnologias e atores envolvidos, foram utilizados os dados de documentos patentarios extraidos da base ORBIT, onde foram selecionados 1635 documentos de patentes sem definicao previa temporal, observando-se um comportamento crescente com a presenca de dois picos, um pequeno entre 1970 e 1990 com 313 documentos patentarios (19%) e outro maior entre 2007 e 2018 com 916 documentos patentarios (56%). Com base no exposto, compreende-se que e viavel um processo de gestao e monitoramento por meio de documentos patentarios, uma vez que estes sao ricos em informacoes estrategicas e tecnicas, especificamente, a maioria dos documentos patentarios no Brasil sobre fertilizantes se referem a fertilizantes orgânicos e de depositantes residentes no Brasil. Logo, e uma estrategia de suma importância para o Brasil o reaproveitamento desses nutrientes e para a disposicao ordenada e ecologicamente correta dos residuos agricolas e agroindustriais e assim diminuir a dependencia brasileira de importacao de fertilizantes.
Relación de la carga de entrenamiento con las emociones y el rendimiento en baloncesto formativo (Relation of training load with emotions and performance in formative basketball)

The objective of the study was to identify the relationships between training load with emotional and performance variables in formative basketball. The participants were 82 players in the formative categories. Internal load, external load, emotional intelligence, perceived performance, and well-being-related variables such as fatigue and muscle pain were measured. The results show that heart rate is related to a higher perception of performance, as well as external load with fatigue. Similarly, fatigue and muscle pain had a strong relationship between them and, in turn, with less score in matches, less perception of performance and negative emotional regulation. The perceived performance relates positively to all the variables of emotional intelligence. With these data, the coaches have more resources and knowledge when it comes to planning and design the training sessions, which will improve performance by athletes. It is recommended to train with intensity without perceiving fatigue or muscular pain, as well as developing the variables of emotional intelligence.
Anti‐cancer combination therapy by co‐delivery of hydrophilic and hydrophobic using dual temperature and pH‐responsive liposomes

A novel combination chemotherapic strategy by co-delivery of doxorubicin (DOX) and mitomycin C (MC) anti-cancers was reported using dual pH and temperature-responsive copolymer-modi ﬁ ed liposomes to achieve superior therapeutic ef ﬁ cacy. The copolymer was prepared using temperature-responsive N -isopropylacrylamide and pH-responsive poly-acrylic acid monomers through reversible addition – fragmentation chain transfer polymerisation and revealed dual pH/temperature-dependent phase transitions proved by differential scanning colorimetric and cloud point measurements. With relatively high encapsulation ef ﬁ ciency of 81.2% for DOX and 77.3% for MC, the prepared polymer-modi ﬁ ed responsive liposomes (PMRLs) have shown enhanced and controlled temperature/pH-dependent release pro ﬁ les and signi ﬁ cantly lower thermal dose thresholds with up to a 250-fold decrease at pH 7.4 and 1000-fold decrease at pH 5.5 compared to the traditional formulations. The temperature/pH-dependent release pro ﬁ le of the drugs was investigated in vitro and cytotoxicity of the carriers was evaluated using both normal and cancerous cell lines. It was found that the two drugs co-loaded PMRLs were revealed synergistic effects on cytotoxicity of the carriers against Michigan Cancer Foundation-7 breast cancer cells. The results revealed that by this combinational regimen, the prepared liposomes have the potential to dramatically decrease the risk of damage to healthy tissues normally caused by liposomal cancer therapy.
IMPORTANCE OF SELF – MANAGEMENT OF PATIENTS WITH CARDIOVASCULAR DISEASE ON HEALTH-RELATED QUALITY OF LIFE

The aim of the paper was to find out what is known about how do people effectively manage their illness, heart and cardiovascular diseases, themselves in the advanced stages of their disease. Material and Metods. An integrative review. Results. Promotion of self-managment in patients with a viable health care strategy in order to maintain health and prevent exacerbations. Optimal treatment of care, patients‘ self-managment promotion reduces the financial costs of treating patients. Increasing the patient‘s ability to achieve a healthy lifestyle, the application of medical recommendations to recognize the symptoms and signs of consultations with health care professionals can reduce repeated hospitalization rates. For health care professionals self-managment education promotion is a great strategy to improve patients‘ quality of life. Conclusions. Self management strategies for people with heart and cardiovascular disease should be related to helping them cope with pain and debilitating symptoms, coping emotionally and adjusting psychosocially to their illness, and alleviating distress associated with symptoms that can not easily be improved. Examples of good practice should be formally evaluated.
The role of factors associated with the course of pregnancy and childbirth in attention deficit hyperactivity disorder (ADHD).

OBJECTIVES Assessment of the prevalence of risk factors associated with the course of pregnancy and childbirth and the condition of the child after birth in agroup of children and adolescents with ADHD and a control group. METHODS 205 unrelated children and adolescents diagnosed with ADHD and 106 primary and secondary school students aged 7-17. Method. Mothers of children and adolescents diagnosed with ADHD, and those from the control group, were asked to provide a medical history in order to obtain data to supplement the Pregnancy and perinatal history questionnaire. RESULTS Statistically significant differences (p < 0.05) were demonstrated for the incidence rates of factors related to the course of pregnancy and childbirth such as: the occurrence of maternal diseases during pregnancy, especially in the I/II trimester, and other problems during pregnancy; exposure to stress and taking medication during pregnancy; smoking during pregnancy; mother's age at childbirth, i.e., < 25 years or > 35 years; use of pain reducing substances during labor and problems with the child during the delivery;an APGAR score in the range of 5-7 points; the occurrence of neonatal jaundice necessitating treatment, especially replacement transfusion; physical anomalies or other congenital problems in the newborn, as well as adaptive problems necessitating neonatal oxygen administration or placement in an incubator. CONCLUSIONS Significantly more frequent occurrence of risk factors related to the course of pregnancy, childbirth and the child's condition after birth in the ADHD group may indicate their potential role in the etiology of ADHD.
The comparison of Linear and Nonlinear pedagogy on the learning of table tennis forehand stroke

Learning of sport skills is a complex process which is influenced by the individual differences. The purpose of the current research was to compare the Linear pedagogy and the Nonlinear pedagogy on the performance and learning of table tennis forehand stroke. This was a semi-experimental study that was carried out on 22 girls (9 - 11year). Random two groups after pre-test, participated in eight sessions to learn. Then, the immediate retention test was conducted, and after four weeks they took the delayed retention and transfer tests. Although, both groups had progress in accuracy scores also the Nonlinear group in all stages of post-intervention scored better marks, statistically, there was no significant difference between two groups (p>0.05). The results suggested that there are extra ways for learning, by searching and finding a proper movement solution can learn more easily, and recommends instructors to use new methods of learning.
Autoeficacia para el desempeño de actividad física en personas mayores

La autoeficacia, concebida como la creencia en poder realizar una tarea a pesar de las dificultades, es uno de los más consistentes predictores de iniciación y mantenimiento de la actividad física en las personas de todas las edades, pero más aún, en edad avanzada. Por lo tanto, esta revisión describe primero la autoeficacia y su distinción de construcciones similares e incorpora la autoeficacia dentro de la teoría sociocognitiva donde se describió por primera vez. Luego, se describen los principales abordajes de diferentes disciplinas para promover la autoeficacia, y, en consecuencia, la actividad física; poniendo foco en la evidencia disponible en el área de ciencias de la salud sobre cómo impulsar las fuentes de esta importante autoconfianza en las personas mayores.
Imaging on the Nanoscale: Super-Resolution Fluorescence Microscopy

Although the resolution of a light microscope is fundamentally limited by diffraction to about half of the wavelength of light, in recent years several techniques have been developed that can overcome this limitation in fluorescence microscopy, allowing imaging with nanometre scale resolution. Many of these techniques are based on photoswitchable molecules that can switch between a bright, fluorescent and a dark, nonfluorescent state. Some of these techniques, as well as their limitations, are discussed.
Exploring the influence of quality management systems in work engagement and psychological empowerment in private institutions of social solidarity

Aiming at exploring the influence of quality management systems (QMS) in staff’s work engagement and psychological empowerment in private institutions of social solidarity (IPSSs), this study performs a comparative analysis between institutions with and without an ISO 9001-based QMS. Data were collected through questionnaires applied to employees from two IPSSs with a certified QMS and two IPSSs without a QMS. Findings show that although employees’ perception about psychological empowerment and engagement are generally higher in IPSS with an ISO 9001-based QMS, these differences are not statistically significant. Nevertheless, in what empowerment concerns, the perception of employees with leading role in IPSS with an ISO 9001-based QMS is significantly greater than the perception of those in IPSS without a QMS. To our knowledge, no previous study has investigated the influence of ISO 9001-based QMS in employees’ work-related attitudes in the third sector; these results contribute thus to new insights concerning a clearly under-researched field.
PET measured hypoxia and MRI parameters in re-irradiated head and neck squamous cell carcinomas: findings of a prospective pilot study

Background: Tumor hypoxia measured by dedicated tracers like [ 18F]fluoromisonidazole (FMISO) is a well-established prognostic factor in head and neck squamous cell carcinomas (HNSCC) treated with definitive chemoradiation (CRT). However, prevalence and characteristics of positron emission tomography (PET) measured hypoxia in patients with relapse after previous irradiation is missing. Here we report imaging findings of a prospective pilot study in HNSCC patients treated with re-irradiation. Methods: In 8 patients with recurrent HNSCC, diagnosed at a median of 18 months after initial radiotherapy/CRT, [ 18F]fluorodeoxyglucose (FDG)-PET/CT (n=8) and FMISO-PET/MRI (n=7) or FMISO-PET/CT (n=1) were performed. Static FMISO-PET was performed after 180 min. MRI sequences in PET/MRI included diffusion-weighted imaging with apparent diffusion coefficient (ADC) values and contrast enhanced T1w imaging (StarVIBE). Lesions (primary tumor recurrence, 4; cervical lymph node, 1; both, 3) were delineated on FDG-PET and FMISO-PET data using a background-adapted threshold-based method. SUV max and SUV mean in FDG- and FMISO-PET were derived, as well as maximum tumor-to-muscle ratio (TMR max) and hypoxic volume with 1.6-fold muscle SUV mean (HV 1.6) in FMISO-PET. Intensity of lesional contrast enhancement was rated relative to contralateral normal tissue. Average ADC values were derived from a 2D region of interest in the tumor. Results: In FMISO-PET, median TMR max was 1.7 (range: 1.1-1.8). Median HV 1.6 was 0.05 ml (range: 0-7.3 ml). Only in 2/8 patients, HV 1.6 was ≥1.0 ml. In FDG-PET, median SUV max was 9.3 (range: 5.0-20.1). On contrast enhanced imaging four lesions showed decreased and four lesions increased contrast enhancement compared to non-pathologic reference tissue. Median average ADC was 1,060 ×10 6 mm 2/s (range: 840-1,400 ×10 6 mm 2/s). Conclusions: This pilot study implies that hypoxia detectable by FMISO-PET may not be as prevalent as expected among loco-regional recurrent, HPV negative HNSCC. ADC values were only mildly reduced, and contrast enhancement was variable. The results require confirmation in larger sample sizes.
A Mixed-Method Study on Innovation Capability Enhancing through Entrepreneurial Education: New Normal Perspective

The outbreak of the COVID-19 pandemic crisis in 2020 is similar to other crises, such as natural disasters, war, macroeconomic mismanagement, and its economic shock has brought great influence to enterprises all over the world. The crisis will lead to a large number of small and medium-sized enterprises (SME) bankruptcy and social unemployment tide. The tense trade war and ideological conflict between China and the United States before the outbreak have brought China's economic development into a severe bottleneck period. The main objective of this study is to analyze the influence of entrepreneurship education on innovation capability among undergraduate students in Guangxi, China. The mixed-method research design is utilized in this study, the quantitative data of 400 senior undergraduates from 3 universities in China were collected by questionnaires, the proposed data analysis has adopted by CB-SEM. A qualitative sample of the in-depth interview was identified as 15 and Nvivo software was utilized for data analysis, including 12 students and 3 instructors from three universities. The current international competitiveness is mainly focused on the technical talents and innovation capability, this study referenced the Triple Helix Model of Innovation that government, university, and industry play the important roles in the innovation ecosystem. The findings revealed the institutional environment and supporting infrastructure have a significant impact on student’s innovation capability, and entrepreneurial capital obtained from entrepreneurship education program is important for the cultivation of innovation capability. This research makes significant theoretical and practical implications to enrich the existing literature of the relationship of entrepreneurship education and innovation capability, and the policymakers of government and universities should encourage the innovation-driven entrepreneurship education practices in the new normal economic environment.
Platinum and palladium doped tin oxide thick film sensors for sensing methane and hydrogen

In this work, platinum (Pt) and palladium (Pd) doped SnO2 thick film sensors have been developed using solid state derived tin oxide powder. Thick film sensors were fabricated on a 1˝x1˝ alumina substrate. The crystal structure and particle size are confirmed by X-ray diffraction (XRD) pattern. The fabricated sensors are tested for varying concentration (1–5%) of hydrogen and methane gas at different operating temperatures (200–350 °C). The effect of Pt and Pd doping have been analysed on different operating temperature, sensitivity and response/recovery time. The doping effects are also very important from view point of the gas selectivity. Based on the experimental results, we have observed the formation of tetragonal structure and particle size of the powders is drastically decreases from 26 to 19 nm after replacing the platinum dopant with palladium. Both the doped sensors have been found to be sensitive for hydrogen as compare to methane however, Pd-doped SnO2 sensor are most selective for hydrogen with very fast response and recovery time (20 s, 101 s) due to the small size effect.
Separation of blood cells using hydrodynamic lift

Using size and deformability as intrinsic biomarkers, we separate red blood cells (RBCs) from other blood components based on a repulsive hydrodynamic cell-wall-interaction. We exploit this purely viscous lift effect at low Reynolds numbers to induce a lateral migration of soft objects perpendicular to the streamlines of the fluid, which closely follows theoretical prediction by Olla [J. Phys. II 7, 1533, (1997)]. We study the effects of flow rate and fluid viscosity on the separation efficiency and demonstrate the separation of RBCs, blood platelets, and solid microspheres from each other. The method can be used for continuous and label-free cell classification and sorting in on-chip blood analysis.