Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of 5-hydroxytryptamine Receptor in the Lower Esophageal Sphincter Regulation Mechanism

As a neurotransmitter and avascular active substance, the 5-hydroxytryptamine (5-HT, serotonin) is widely distributed in the central nervous system and surrounding tissues. The 5-HT can play its role by acting on its corresponding 5-HT receptor. Nowadays, the 5-HT receptor can be classified into seven, according to different signal transduction method of receptors, the 5-HT3 receptor belongs to the ligandgated ion channels, while other six 5-HT receptors are involved into the G protein-coupled receptors and play the biological role by binding to specific G protein-coupled receptors (GPCRs) on the surface of the cell membrane. The 5-HT plays an important role in the brain-gut information transmission and studies showed that the physiological stimulations like having meals, and pathological stimulations like ischemia and stress could promote the release of the 5-HT. In the gastrointestinal tract, the 5-HT is closely related to gastrointestinal sensitivity, gastrointestinal movement and secretion regulation, as well as many gastrointestinal dysfunction disorders, such as gastrointestinal power and visceral sensitivity abnormality and abnormalities of brain-gut axis.
Acceptance Factors of Car Insurance Innovations: The Case of Usage-Based Insurance

Usage-Based Insurance (UBI) is an application of Intelligent Transportation Systems (ITS) in the context of car insurance. UBI refers to insurance models in which insurers collect driving data using a telematics device. Based on the collected information, insurers can offer individual discounts depending on driving behaviour and provide feedback about each trip. Although there are plenty of advertising materials about the benefits of UBI, its user acceptance and usability have not received much research attention so far. To cover this gap, we conducted two user studies: semi-structured interviews with UBI users and a qualitative analysis of 186 customer inquiries concerning a UBI program from a web forum of a German insurer. We found that UBI can benefit drivers, insurers and society. Moreover, the country driving conditions, the policy conditions, the users’ perceived driving style, the perception of UBI, and the premium reduction influence UBI acceptance. Regarding traffic safety, some of our participants were concerned that UBI may provoke dangerous driving behaviour under certain circumstances. Finally, we make recommendations for insurers derived from users’ views, such as to provide to drivers more control over the user interface and over the way driving feedback is given to them. Concerning the driving scores, the ways in which they are calculated should be more
Kahoot!: EFL instructors’ implementation experiences and impacts on students’ vocabulary knowledge

Enthusiasm for mobile-assisted language learning (MALL) in EFL classrooms at Korean universities is substantial and growing among both instructors and students. The question of how effective MALL is for English learning, however, remains largely unanswered. This pilot study seeks to explore the efficacy of the mobile application Kahoot! while simultaneously evaluating the implementation of the application through the eyes of the instructors who use the program. This study uses a mixed-methods quasi-experimental design incorporating inferential statistics, which are complemented by survey and focus group methodology for qualitative analysis. While the experimental group showed a marked increase in vocabulary knowledge, the differences failed to be statistically significant for this small sample size and short duration. However, the instructors provided critical insights into the use of Kahoot! in the EFL classroom that will improve pedagogy and guide additional and more rigorous future research.
Near‐infrared spectroscopy for within‐field soil characterization: small local calibrations compared with national libraries spiked with local samples

The advantage of using near‐infrared spectroscopy to increase sample point density in soil mapping on farms relies on the number of conventional laboratory analyses for the calibrations being kept to a minimum. This study compared the performance of small farm‐scale calibrations (25 samples) with a larger national soil library (396 samples) and tested whether a site‐specific sample set selected from the national library, consisting of the 50 samples that were spectrally most similar to those of the local sites, could increase performance. In addition, the national library and selected subsets were augmented (‘spiked’) with up to 25 local calibration samples to test whether that had any additional effect on prediction errors and bias. Calibrations were made for predicting within‐field variation in clay, silt, sand, soil organic carbon (SOC), pH and phosphorus. Selecting a subset of samples from the national library did not improve the results compared with using the entire national library. However, spiking both libraries with local samples reduced the root mean squared error of prediction (RMSEP) considerably, mainly through a decrease in bias, and often resulted in comparable results to the local calibrations. There was a tendency for better clay and SOC predictions from spiking a reduced national library compared with spiking the entire national library, sometimes even resulting in better predictions than using the local calibrations. However, using local calibrations seems to be the best alternative for predicting soil properties at the farm or field scale, even with as few as 25 samples.
Unmanned Aerial Vehicle enabled Internet of Everything: Opportunities and Challenges

—The recent advances in information and communication technology (ICT) have further extended Internet of Things from the sole “things” aspect to the omnipotent role of “intelligent connection of things”. Meanwhile, the IoE realization meets critical challenges including the restricted network coverage and the limited resource of existing network technologies. Recently, Unmanned Aerial Vehicles (UAVs) have attracted signiﬁcant attentions attributed to their high mobility, low cost, and ﬂexible deployment. Thus, UAVs may potentially overcome the challenges of IoE. This article presents a comprehensive survey on opportunities and challenges of UAV-enabled internet of everything (IoE). We ﬁrst present three critical expectations of IoE: 1) scalability requiring a scalable network architecture with ubiquitous coverage, 2) intelligence requiring a global computing plane enabling intelligent things, 3) diversity requiring provisions of diverse applications. Thereafter, we review the enabling technologies to achieve these expectations and discuss four intrinsic constraints of IoE (i.e., coverage constraint, battery constraint, computing constraint, and security issues). We then present an overview of UAVs. We next discuss the opportunities brought by UAV to IoE. Additionally, we introduce a UAV-enabled IoE (Ue-IoE) solution by exploiting UAVs’s mobility, in which we show that Ue-IoE can greatly enhance the scalability, intelligence and diversity of IoE. Finally, we outline the future directions in Ue-IoE.
Blockchain Based Secure Traffic Police Assistant System

: There are large numbers of vehicles in the populated country like India. It’s a very common scenario that traffic police came across some vehicle random vehicle and had some doubt in mind but do not have in hand information about that vehicle and end up leaving that thought. Sometimes this may result in some disaster. With the advent of technology, there are mobile applications and web based systems are available to ease up the process by which traffic police can fine the vehicle owner or people can pay the fine online. But yet there is no system is available through which traffic police can get all the details about the particular vehicle. This motivated us to design and developed an application thorough which traffic police can get all the information right from owner of the vehicle to its RC book and insurance status on just one click. Looking at the chances of data tampering, we have also played an attention to the data security and used blockchain for creating distributed, robust and tempered proof system. In this paper we have discussed traffic police assistance system, which can scan the vehicle number plate, identify the number and provide the all the information and documents stored against that vehicle number. To address the issue of data security and alteration of sensitive data blockchain is used so that any alteration can be monitored. As the complete information process is dependent on how correctly the vehicle number is identified, so the number plate recognition module is tested thoroughly under various conditions. Finally user feedback is taken and analyzed to evaluate the feasibility and usability of the proposed application
The Reliability Analysis of Rotary Kiln A

Rotary Kiln as a pyroprocessing device is used to raise the temperature of the material to a high temperature (calcination) in a continuous process. By looking at the constraints on PT. Meratus Jaya Iron & Steel, whose production machines often have breakdowns, is a fundamental reason for researchers to increase the reliability level of PT. Meratus Jaya Iron & Steel. The research was conducted on the Rotary Kiln Machine made in Germany which plays a high enough role in the company. The method used is the Reliability with Mean Time to Repair Method (MTTR). From the results of calculations of Reliability with MTTR on Rotary Kiln A is Reliability at the time of 296 hours operation results obtained by 0.5371 and MTTR 537.7732. The higher the reliability value, the better the machine used in the operation process.
Factors associated with depression and the relationship to quality of life among Saudi women with breast cancer

Background and objective: Breast cancer is the most common malignancy among women worldwide, diagnosis and treatment and the months following primary therapy associated with different psychological symptoms that affect quality of life (QoL) in most women with breast cancer. The aim of this study was to identify the relationship between depression and quality of life QoL among Saudi women with breast cancer.Methods: Design: This is a descriptive, cross-sectional study. Methods: A convenience sample of 370 women with breast cancer was recruited from the out-clinic in King Faisal Specialist Hospital \& Research Center (KFSH&RC). Data were collected using self-report tools derived from the Patient-Reported Outcomes Measurement Information System (PROMIS) Emotional Distress-Depression-Short Form; the EORTC quality of life questionnaire (QLQ) (EORTC QLQ-C30, v.3.0 and EORTC QLQ-BR23); and from the Demographic and Clinical Data Sheet.Results: The correlation between depression and global health status with functioning subscales for the women was negative (Pearson’s r = -.357, p < .001; r = -.368, p < .001); whereas a positive correlation was found between depression and symptom subscales, together with its items.Conclusions: This study shows that depression is associated with QoL among Saudi women diagnosed with breast cancer. Therefore, depression affects upon QoL among the breast cancer population. However, enhancement of mental health statuses and psychological interventions helps to reduce the severity of depression and improves health related QoL among this population.
Whole genome sequence-based prediction of resistance determinants in high-level multidrug-resistant Campylobacter jejuni isolates in Lithuania Aksomaitiene,

Spread of antibiotic resistance via mobile genetic elements associates with transfer of genes providing resistance against multiple antibiotics. Use of various comparative genomics analysis techniques enables to find intrinsic and acquired genes associated with phenotypic antimicrobial resistance (AMR) in Campylobacter jejuni genome sequences with exceptionally high-level multidrug resistance. In this study, we used whole genome sequences of seven C. jejuni to identify isolate-specific genomic features associated with resistance and virulence determinants and their role in multidrug resistance (MDR). All isolates were phenotypically highly resistant to tetracycline, ciprofloxacin, and ceftriaxone (MIC range from 64 to ≥256 μg/mL). Besides, two C. jejuni isolates were resistant to gentamicin, and one was resistant to erythromycin. The extensive drug-resistance profiles were confirmed for the two C. jejuni isolates assigned to ST-4447 (CC179). The most occurring genetic antimicrobial-resistance determinants were tetO, beta-lactamase, and multidrug efflux pumps. In this study, mobile genetic elements (MGEs) were detected in genomic islands carrying genes that confer resistance to MDR, underline their importance for disseminating antibiotic resistance in C. jejuni. The genomic approach showed a diverse distribution of virulence markers, including both plasmids and phage sequences that serve as horizontal gene transfer tools. The study findings describe in silico prediction of AMR and virulence genetics determinants combined with phenotypic AMR detection in multidrug-resistant C. jejuni isolates from Lithuania.
Journal of Management and Tourism Research Volume 2 Issue 2 (2019) 71-84

Generosity and cooperation of the residents is essential for the attainment and sustainability of tourism development goals in country. Moreover, the intention of residents to involve in tourism development lead to a solid foundation for a successful tourism industry in the country. The perception of local residents towards tourism impacts determines the success and failure of any tourism developmental project. Hence, this study attempts to investigate the influential impact of the residents’ perception towards tourism impacts and their intention to involve in tourism development. The perception of 200 randomly selected residents was surveyed employing a structured questionnaire, from 10 Grama Niladari divisions using stratified sampling technique, in Negombo coastal area which is one of the most attracted tourist destination with ample number of tourism developmental projects. The results of regression analysis reveal that the effect of residents’ perception towards economic impacts and environmental impacts are significantly influential on their intention to involve in tourism development while residents’ perception towards socio-cultural impacts does not effect on intention to involve in tourism development. Thus, the study recommends the respective authorities to take action to minimize the negative economic and environmental impacts while increasing the positive impacts that eventually leads an upsurge intention of residents to involve in tourism development. Effect of Residents’ Perception towards Tourism Impacts on Intention to Involve in Tourism Development; Special Reference to Coastal Area in
Hazelnut: A Valuable Resource

Hazel (Corylus avellana L.) nutshell is one of the most consumed and most appreciated nut fruit all over the world. It is believed to have constituted a basic food in early prehistory, in temperate zones of the globe, such as for example Europe. Presently the hazelnut production is mainly concentrated on the Black Sea coast of Turkey, but other countries are also important producers, like for example Portugal, situated on the western Europe, in the Iberian Peninsula. The objective of this work is to make a review about the worldwide importance of hazelnut, their usages, including gastronomic and industrial applications, as well as some ways that allow adding value to this fruit, making it an even more valuable resource. The advantages include higher income for produces, lower environmental impacts and valorisation of residues improving sustainability and providing valuable products for consumers and/or ingredients to incorporate into those products.
Pemeriksaan Logam Berat Cadmium (Cd) dan Plumbum (Pb) pada Lipstik yang Beredar di Pasar Brayan Medan Timur Secara Spektrofotometri Serapan Atom (SSA)

Telah dilakukan penelitian Pemeriksaan Logam Berat Cadmium (Cd) dan Plumbum (Pb) Pada Lipstik Yang Beredar di Pasar Brayan Medan Timur Secara Spektrofotometri Seraparan Atom. Penelitian ini dilatar belakangi dengan adanya lipstik yang menjadi tidak aman bila tercemar logam berat yang dapat menimbulkan efek buruk terhadap kesehatan. Penelitian ini dilakukan di Unit Pelayanan Teknis Laboratorium Kesehatan Daerah Dinas Kesehatan Provinsi Sumatera Utara dengan tujuan untuk mengetahui ada tidaknya dan kadar logam berat Cadmium dan Plumbum pada lipstik yang beredar di Pasar Brayan Medan Timur. Penelitian ini bersifat eksperiment laboratorium dengan metode pengambilan sampel secara acak sebanyak 5 sampel dari seluruh populasi yang beredar di Pasar Brayan Medan Timur dengan teknik analisa data yang diperoleh dari data primer dan sekunder, disajikan dalam bentuk tabulasi yang dinarasikan dengan hasil logam berat Cadmium (Cd) dari 5 sampel diperoleh hasil analisa kualitatif dan kuantitatif dengan sebanyak dua sampel yang positif (sampel dua = 5,000 mg/L dan sampel empat = 4,950 mg/L). sedangkan pada logam berat Plumbum (Pb) diperoleh empat sampel positif (sampel satu = 0,915 mg/L, sampel tiga = 0,295 mg/L, sampel empat = 6,960 mg/L dan sampel lima = 1,515 mg/L, dari hasil keseluruhan sampel yang mengandung logam berat (Cd dan Pb) diperoleh kadar dibawah standar baku ( BPOM RI Persyaratan cemaran logam Cadmium < 5 mg/L dan Plumbum < 20 mg/L atau mg/kg. Nomor HK.03.1.23.07.11.6662 tahun 2011) dengan ini perlu dilakukan pengawasan yang lebih intensif terhadap kosmetik tidak teregrestasi yang beredar di masyarakat, khususnya masyarakat Pasar Brayan Medan Timur.
Design Considerations and Comparative Analysis of Cross Layer Approaches for Terrestrial & Underwater Wireless Sensor Networks

Abstract Due to the ever increasing demand of the deployment of terrestrial and underwater wireless sensor networks in Internet of Things applications to sense and monitor physical and environmental conditions, it becomes highly essential to design an efficient cross layer framework for Terrestrial and Underwater Wireless Sensor Networks to conserve energy & achieve low delay by considering the design issues involved and challenges encountered in these environments. This paper provides a detailed study on the design considerations and comparative analysis of Cross Layer approaches for Terrestrial & Underwater Wireless sensor networks. The cross-layer design supports in leveraging the performance of wireless sensor networks, and conservation of resources like storage, battery and bandwidth etc. Most of the cross layer architecture designs focus either on limited layers such as MAC and Routing, ignoring the functionalities of other layers or integrate all layer parameters as a single module resulting in increased complexity. This paper proposes a novel Hybrid Cross Layer Model (HCLM) which combines layer interaction through integration and Interface to achieve a good performance across the system. The main aim of the proposed hybrid cross layering model is to achieve a blended efficiency of the layers - Physical, MAC, Routing and Application. This approach, performs the cross layering in two parts - considering one at the middle layers (MAC and Routing) and other at the extreme edge layers (PHY and Application). The proposed model assures the leverage in performance along with the complexity of balancing and maintenance of good data rate resulting in energy conservation.
Sol–Gel Electrophoretic Deposition for the Growth of Oxide Nanorods

By combining sol–gel processing with electrophoretic deposition, we have developed a new method for the growth of oxide nanorods. Both single metal oxides (TiO2, SiO2) and complex oxides—BaTiO3, Sr2Nb2O7, and Pb(Zr0.52Ti0.48)O3—have been grown by this method. Uniformly sized nanorods 45–200 nm in diameter and 10 μm in length can be grown over large areas with near unidirectional alignment. The nanorods have the desired stoichiometric chemical composition and crystal structure, after firing to 500–700 °C for up to one hour.
OP-HURU200061 1..26

endometriosis: a review of preclinical and clinical studies Gabriela F. Meresman, Martin Götte *, and Matthias W. Laschke 3 Institute of Biology and Experimental Medicine (IBYME-CONICET), C1428ADN Buenos Aires, Argentina Department of Gynecology and Obstetrics, Münster University Hospital, 48149 Münster, Germany Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg, Germany
Physical and chemical stability of the bentonite buffer

Bentonite clay intended for use as a buffer around the waste canisters will form a stable gel under the expected groundwater compositions at potential repository sites. A literature survey has been made of the forces involved that attract and those that repel the clay particles under different conditions. Especially the repulsive forces and how these are influenced by the water chemistry have been studied, because in low ionic strength waters these forces can become so strong that the gel becomes unstable. Results from measurements described in the literature are also presented. The bentonite backfill surrounding the waste canister may be eroded by swiftly flowing water in the fractures that intersect the deposition hole. The clay gel acts as a Bingham fluid and there is a minimum shear stress that water must exert on the gel to mobilise the particles. The shear stress at the gel/water interface has been estimated for a wide range of hydraulic conditions that could be expected even under very high gradients that could be generated by a receding ice front during an ice age. The shear stress has been compared to the Bingham yield stress. The latter is influenced both by the pore water chemistry as well as by the density of the clay gel. The stability of the clay is strongly influenced by the calcium and other divalent cation concentrations in the pore water. If the clay is exposed to water with a calcium concentration that is lower than the critical coagulation concentration, the CCC, the clay gel can form a sol and the clay particles can be carried away by the passing water. Using boundary layer theory for diffusing species we have calculated the rate of transport of calcium from the clay to a groundwater that flows and contacts the clay in the fractures that intersect the deposition hole. Based on this a simple illustrative entity called the equivalent flowrate is introduced and used to derive a simple expression that relates the loss of clay to the hydraulic properties, the CCC, the content of soluble calcium minerals and to the composition of the approaching groundwater.
A new meso–meso directly-linked corrole–porphyrin–corrole hybrid: synthesis and photophysical properties

A first example of a directly-linked corrole–porphyrin–corrole (Cor–Por–Cor) triad has been targeted and synthesized. The new hybrid has been fully characterized by 1H NMR, 19F NMR and 2D NMR spectroscopy. The fluorescence quantum yield of the triad is three times higher than that of meso–meso directly linked porphyrin trimers. All the three chromophores assume a near orthogonal geometry with respect to the neighbour.