Miracle-dz/UniFAR-FTUs huggingface dataset:
Pentacyclo[8.2.1.14,7.02,9.03,8]tetradeca-5,11-diene

The title compound, C14H16, was prepared through [2 + 2] cycloaddition of norbornadiene. There are two independent molecules in the asymmetric unit: each is centrosymmetric with the centroid of the four-membered ring located about an inversion center. Each molecule possesses an exo–trans–exo conformation.
Di-μ-bromido-bis{[N,N-dimethyl-N′-(thiophen-2-ylmethylidene)ethane-1,2-diamine]copper(I)]}

In the crystal structure of the title compound, [Cu2Br2(C9H14N2S)2], the molecule resides about a crystallographic inversion center. The coordination sphere around each copper ion has a distorted tetrahedral geometry, with ligation by two bridging bromide ions, an amine N atom and an imine N atom. The thiophene ring is disordered over two sites, with occupancies of 0.719 (3) and 0.281 (3). Weak C—H⋯π interactions feature in the crystal packing.
5-Isopropylidene-1,3-dithiolo[4,5-d][1,3]dithiole-2-thione

The title compound, C7H6S5, contains a 5-ylidene-1,3-dithiolo[4,5-d][1,3]dithiole-2-thione framework, which is an important synthetic precursor of multi-dimensional organic superconductors and conductors. The molecular framework is planar with an r.m.s. deviation of 0.012 Å for the non-H atoms. In the crystal structure, molecules are linked by short intermolecular S⋯S interactions [3.501 (5) and 3.581 (4) Å], constructing a zigzag molecular tape network along the c axis.
(5-Methoxy-1H-indol-3-yl)acetonitrile

In the title compound, C11H10N2O, the O atom and the C atom of the methylene group deviate only slightly [0.029 (3) and 0.055 (3) Å, respectively] from the approximately planar ring system (r.m.s. deviation = 0.013 Å). In the crystal, N—H⋯O hydrogen bonds link the molecules into zigzag chains running along the b axis.
3-Phenyl-1-(pyrrol-2-yl)prop-2-en-1-one

The title molecule, C13H11NO, is almost flat, the angle between the pyrrole and the phenyl rings being 10.9 (1)°. The atoms of the central C3O unit are coplanar, with a mean deviation from the plane of 0.001 (1) Å. The angles between this plane and the pyrrole and phenyl rings are 3.3 (1) and 8.0 (1)°, respectively. The molecules form centrosymmetric dimers through a pair of N—H⋯O hydrogen bonds with an R 2 2(10) motif.
2-(3,4-Dimethyl-5,5-dioxo-2H,4H-pyrazolo[4,3-c][1,2]benzothiazin-2-yl)-N′-(2-thienylmethylidene)acetohydrazide

In the title molecule, C18H17N5O3S2, the heterocyclic thiazine ring adopts a twist boat conformation, with the S and N atoms displaced by 0.480 (7) and 0.205 (8) Å, respectively, on opposite sides of the mean plane formed by the remaining ring atoms. The pyrazole and benzene rings are tilted at an angle of 10.9 (2)° with respect to one another. The crystal structure is stabilized by intermolecular N—H⋯O and C—H⋯N hydrogen bonds, resulting in dimers forming nine-membered rings of graph-set motif R 2 2(9). In addition, intermolecular C—H⋯O interactions result in chains of molecules along the c axis, further consolidating the crystal packing.
2′-Methyl-3,5-diphenylspiro[4,6-dioxa-2-azabicyclo[3.2.0]hept-2-ene-7,4′-isoquinoline]-1′,3′(2′H,4′H)-dione

In the title compound, C25H18N2O4, the tetrahydropyridine ring adopts a distorted envelope conformation with the spiro C atom at the flap position [deviation = 0.470 (2) Å]. The dihydro–oxazole ring is planar (r.m.s. deviation = 0.013 Å) and it makes dihedral angles of 73.43 (8) and 4.24 (8)° with the two attached phenyl rings. The dihedral angle between oxetane and oxazole planes is 67.44 (9)°. In the crystal structure, C—H⋯O hydrogen bonds link neighbouring molecules into zigzag chains along the b axis and these chains are linked via C—H⋯π interactions.
(2E)-3-(3-Bromo-4-methoxyphenyl)-1-(4,4′′-difluoro-5′-methoxy-1,1′:3′,1′′-terphenyl-4′-yl)prop-2-en-1-one

In the title compound, C29H21BrF2O3, the dihedral angles between the central anisole ring and the pendant fluorobenzene rings are 48.86 (19) and 31.89 (18)°. The dihedral angle between the anisole ring and the 1-bromo-2-methoxybenzene ring linked via the enone bridge is 82.95 (17)°. In the crystal, C—H⋯O hydrogen bonds link the molecules into C(11) chains propagating along [010].
2,2′-Dimethyl-4,4′-bipyridine

In the crystal structure of the title compound, C12H12N2, the molecule is twisted around the central C—C bond, with a dihedral angle of 8.32 (5)° between the mean planes of the pyridyl rings. The crystal structure is stabilized by arene stacking interactions, with a distance of 3.81 (1) Å between the ring centroids.
Factores predictivos de discapacidad funcional y muerte a 30 días en sujetos con infarto cerebral agudo: Resultados del Registro Nacional Mexicano de Enfermedad Vascular Cerebral (Estudio RENAMEVASC)

Background: Cerebrovascular diseases are the second cause of death worldwide and 85% of deaths occurred in developing countries as Mexico. Objective: To determine the predictive factors associated to short-term poor outcome or death in patients with acute ischemic stroke in Mexico. Patients and methods: From the RENAMEVASC registry (by the Spanish eponym: REgistro NAcional Mexicano de Enfermedad VAScular Cerebral), we analyzed 891 patients with acute ischemic stroke requiring hospital care. Patients were classified as cases (n367) when clinical outcome at 30 days showed a Rankin score of 4-6 (severe disability or death) and as Controls (n = 524) when they had a Rankin score of 0-3 (good outcome). Demographics, clinical, radiographic, and hospital complications variables were compared between both groups. Results: Case fatal ity rate was 19.6% and severe disabi l i ty was observed in 21.5% of cases. Var iables that were associated to poor outcome or death included: hemispheric infarction (OR 14.4; p < 0.001), medical hospital complications [cardiac arrhythmia (OR 12.7; CONTRIBUCIÓN ORIGINAL
5-Benzoyl-2-(1H-indol-3-yl)-4-(4-methylphenyl)-4,5-dihydrofuran-3-carbonitrile

The furan ring in the title compound, C27H20N2O2, adopts a twisted conformation about the sp 3—sp 3 bond. The molecular structure is stabilized by an intramolecular C—H⋯O interaction which generates an S(6) ring motif. The crystal packing is stabilized by N—H⋯O and C—H⋯O interactions generating centrosymmetric R 2 2(18) and C(6) chain motifs, respectively. A weak C—H⋯π interaction is also observed.
1-(2-Hydroxy-3,5-dimethoxyphenyl)ethanone

In title compound, C10H12O4, all of the non-H atoms lie approximately in a plane with the largest deviation being 0.061 (2) Å. An intramolecular O—H⋯O hydrogen bond generates an S(6) ring motif. No classical intermolecular hydrogen bonding occurs, with only van der Waals forces stabilizing the crystal structure.
6-Bromo-1-methyl-4-[2-(4-methylbenzylidene)hydrazinylidene]-3H-2λ6,1-benzothiazine-2,2-dione

In the title compound, C17H16BrN3O2S, the two fused rings are twisted by a dihedral angle of 6.61 (15)°. The thiazine ring adopts a sofa conformation. The toluene ring is oriented at dihedral angles of 15.5 (2) and 20.6 (2)° with respect to the bromobenzene and thiazine rings, respectively. The benzylidene system is approximately planar [r.m.s. deviation = 0.0388 Å]. In the cyrstal, weak intermolecular C—H⋯O hydrogen bonds connects the molecules into a chain along the b axis.
Reconstrução mamária imediata com expansor de tecido: estudo retrospectivo

Introducao: As reconstrucoes mamarias tornaram-se parte integrante do tratamento docâncer de mama, fornecendo melhor qualidade de vida as pacientes mastectomizadas. Objetivo:O proposito do estudo e mostrar a experiencia do autor com reconstrucao mamariaimediata em dois tempos operatorios com a utilizacao do expansor de tecido / implantede silicone. Metodo: O trabalho compreendeu 39 pacientes com diagnostico de câncer demama submetidas a mastectomia poupadora de pele e reconstrucao imediata com expansorprovisorio de pele posicionado em bolsa submuscular total e posterior substituicao porprotese de silicone no periodo de junho de 2002 a julho de 2007. Resultados: O indice decomplicacoes pos-operatorias foi de 25,58%. Conclusao: A reconstrucao mamaria imediataem dois estagios cirurgicos e um metodo de simples execucao, seguro e flexivel. Introduction: Reconstruction has become a fundamental part of breast cancer treatment,improving the quality of live of women submitted to mastectomy. Objective: The purposeof this study is to demonstrate the author's experience in immediate breast reconstructionin two stages with tissue expander / silicone implant. Method: This paper included 39patients with a cancer diagnostic were performed a skin sparing mastectomy method andimmediate reconstruction with tissue expander placed in submuscular pocket and exchangefor a permanent implant between June of 2002 and July 2007. Results: General rate ofcomplications was 25.58%. Conclusion: The immediate breast reconstruction in two-stageis a simple method, safe and flexible.
A Review on Photo Voltaic MPPT Algorithms

A photovoltaic generator exhibits nonlinear voltage-current characteristics and its maximum power point varies with solar radiation and cell temperature. A Dc/Dc power converter is used to match the photovoltaic system to the load and to operate the PV (photo voltaic) cell array at maximum power point. Maximum Power Point Tracking (MPPT) is a process which tracks one maximum power point from PV array input, varying the ratio between the voltage and current delivered to get the most power it can. There are different techniques proposed with lot of algorithms are being used in the MPPT controller to extract the maximum power. It is very difficult for the photo voltaic designers, researchers and academic experts to select a particular MPPT technique for a particular application which requires the background knowledge and comparative features of various MPPT algorithms. This paper will be avaluable source for those who work in the photo voltaic generation, so its objective is to review the main MPPT algorithms in practice and analyzes the merits and demerits with various factors.
1,2-Bis(2,4-dinitrophenyl)disulfane

In the title molecule, C12H6N4O8S2, the dihedral angle between the benzene rings is 77.00 (8)°. The mean planes of the nitro groups are twisted slightly from the benzene rings, forming dihedral angles in the range 2.3 (2)–8.6 (3)°. The S—S bond length is 2.0458 (7) Å. Each S atom is essentially coplanar with the benzene ring to which it is attached, with deviations from the ring planes of 0.0163 (5) and 0.0538 (5) Å. In the crystal, molecules are linked through weak C—H⋯O hydrogen bonds, forming a two-dimensional network parallel to (001).
Methanol{2-methoxy-6-[(2-oxidopropyl)iminomethyl]phenolato}dioxidomolybdenum(VI)

In the structure of the title compound, [Mo(C11H13NO3)O2(CH3OH)], the MoVI ion is octahedrally coordinated by two oxide O atoms, the N atom and two deprotonated OH groups of the tridentate Schiff base ligand 2-methoxy-6-[(2-oxidopropyl)iminomethyl]phenolate and by a methanol O atom. In the crystal structure, two complexes are linked via O—H⋯O hydrogen bonds, yielding a centrosymmetric arrangement involving the methanol hydroxy group and one of the ligand O atoms coordinated to the MoVI ion.
Bis(acetato-κO)bis(4,5-dimethylbenzene-1,2-diamine-κN)zinc

The structure of the title compound, [Zn(CH3COO)2(C8H12N2)2], has one half molecule in the asymmetric unit. The ZnII atom is situated on a twofold rotation axis and is tetrahedrally coordinated by two N and two O atoms. The crystal packing displays intermolecular N—H⋯O hydrogen bonds and intramolecular N—H⋯O and N—H⋯N hydrogen bonding.
1-(3-Chloro-4-fluorophenyl)-5-(2-diazoacetyl)-4-phenylpyrrolidin-2-one

In the title compound, C18H13ClFN3O2, the pyrrolidine ring adopts an envelope conformation and the planar part is rotated by 4.3 (6)° from the plane of the benzene ring and is almost perperdicular both to the diazoacetyl unit [dihedral angle = 78.93 (7)°] and the phenyl ring [dihedral angle = 86.07 (7)°]. In the crystal, molecules are linked into a three-dimensional framework by C—H⋯O interactions. The molecular conformation is stabilized by an intramolecular C—H⋯O hydrogen bond.
Técnica pessoal para obtenção de enxertos ósseos cranianos

Resumo O objetivo deste artigo foi relatar o desenvolvimento de técnica pessoal para obtenção de enxerto ósseo da calota craniana e divulgá-la entre os neurocirurgiões brasileiros. Essa técnica foi empregada em 101 pacientes que apresentavam necessidade de reconstrução óssea da maxila e/ou da mandíbula. A técnica apresenta o diferencial de determinação da profundidade do crânio por meio de trepanações parciais realizadas na região anterior e posterior do osso parietal para, posteriormente, realizar a remoção do enxerto. Como conclusão, a técnica mostra-se segura e eficiente e pode ser aplicada a qualquer paciente que necessita de cirurgia reconstrutiva.
Molecular diagnosis of metabolic fast growth related diseases in broiler

Pulmonary Hypertension Syndrome (PHS) and lameness are important metabolic diseases that affect rapidly growing broilers. The research reported in the first section of this dissertation focused on developing qPCR assays to identify differences in the expression levels of four candidate genes possibly associated with PHS: angiotensin II type 1 receptor (AGTR1): urotensin receptor 2D (UTS2D); serotonin receptor/transporter type 2Bn (HTR2B); and angiotensinogen cleaving enzyme (ACE). Expression levels of these candidate genes were examined in four different tissues. We established ribosomal protein S14 (RPS14) and RNA polymerase subunit 2B (RP2B) as suitable reference genes because they showed the most consistent deltaCt values as compared to TAT-Box binding protein (TBP) and β2-microglobulin (β2M). We found a wide range of expression variation of HTR2B and AGTR1 in blood compared to lung, liver, and kidney, indicating that blood expression levels of these candidate genes potentially will provide a minimally invasive assessment of susceptibility to PHS. Lameness attributable to Bacterial Chondronecrosis and Osteomyelitis (BCO) has been associated with a wide range of bacterial species. In the second section of this thesis 16S ribosomal RNA was used to identify bacteria causing BCO in broilers. Staphylococcus species were the main bacterial species isolated from BCO lesions and the blood. Staphylococcus agnetis was the principal species isolated from the majority of the bone and blood samples collected from lame broilers that had been hatched in two different hatcheries in two independent experiments. Staphylococcus species also were isolated from the blood of several apparently
Thyroid disorders in pregnancy-experience from north east India.

Aims: Thyroid dysfunction is commonly encountered in pregnancy and can affect maternal and Fetal outcomes. Limited data are available from north east India on the prevalence of various thyroid disorders in pregnancy. The present study was hence conducted to evaluate the prevalence of thyroid disorders in a large government hospital in Assam. Study Design: Prospective cohort study. Place and Duration of Study: Sample: Department of endocrinology and department of obstetrics, Gauhati medical college, Guwahati between may 2011 to April 2013. Methodology: Pregnant women irrespective of gestational age attending the antenatal clinic of Gauhati medical college were screened for thyroid dysfunction by estimation of serum free t34 (FT4), TSH and thyroid peroxidase antibodies (TPOAB). Subjects with known thyroid disorders, chronic illness or on medications known to affect thyroid status were excluded from the study. Results were interpreted as per the American thyroid association (ATA) 2011 guidelines. Results: A total of 542 pregnant women were enrolled for this prospective cohort study. The mean age was 23.85±4.04 yrs. Of the 542 women screened, 69.18% were Euthyroid, 21.58% had subclinical hypothyroidism (SCH), 5.35% had overt hypothyroidism (OH), hyperthyroidism was Original Research Article Saikia et al.; BJMMR, 10(12): 1-7, 2015; Article no.BJMMR. 20534 2 observed in 2.39% and 1.47% had gestational Thyrotoxicosis. TPOAB were positive in 18.08% of women. Conclusion: A high prevalence of thyroid disorders specially hypothyroidism were seen in this study using the newer ATA diagnostic criteria emphasizing the need for screening of all women during pregnancy.
Tech(xt)s

Two of the most productive links between text and technology resulted in hypertexts and interactive fiction. Has this union of text and technology taken two totally different paths? Hypertexts, originally thought to be entirely new modes of expression for mass literature, have been largely relegated to highly academic textual experimentation, while narratives and stories in PC and console games are told through graphics, sound, streaming video and 3D acceleration. Text is completely absent or relegated to on-screen, subtitled dialogue. Can we do anything that reunites text and technology to end the "all-text or no-text" divergence? Hypertextual authors and computer games designers must consider many issues as they move forward. Multimedia artists and developers of next-generation handheld devices are inheriting a wonderful legacy of interconnection between text and technology. After almost 6,000 years of unity, now is not the time for separation.
Science of Pranayam and Homeopathy

Modern medical science has shown unequivocally that Pranayam helps in toning the mind and body. However the exact mechanism of how Pranayam helps in toning the body and mind has still remained a mystery. Recent researches have shown that nanoparticles (particle size of 10-30 nanometers which are almost 10-20 times smaller than those emitted in cigarette smoke), can directly reach the brain through nose breathing and bypass the blood-brain-barrier (BBB). This process may throw some light on how Pranayam affects the mind and body.
A phase I trial of AVN944 in patients with advanced hematologic malignancies

14026 Background: AVN-944 is an inhibitor of inosine monophosphate dehydrogenase (IMPDH), an enzyme that catalyzes the rate- limiting step in guanine nucleotide synthesis, and induces apoptosis in malignant hematopoietic cell lines in vitro. Methods: This phase I study employed open-label dose escalations in patients (pts) with relapsed, refractory hematologic cancers with safety, pharmacokinetic (PK), pharmacodynamic, & efficacy endpoints. Between 12/05 and 1/07 a total of 70 cycles of AVN944 at 25 (7pts), 50 (6pts), 75 (7pts), 100 (7pts) or 125 mg (3pts) b.i. d. orally X 21d every 28d were administered to 30 pts with AML (12), ALL (2), CLL (3), and multiple myeloma (13). Peripheral blood mononuclear cell (PBMC) or leukemic blast samples were obtained from all pts pre and post-receiving AVN944 to determine effects on GTP pools, IMPDH activity, and to correlate these changes to response in a 32-gene set that relates directly to cellular pathways dependent upon guanine nucleotide biosynthesis. Results: Phar.
Medical Expenditure Attributable to Overweight and Obesity in Adults with Ischemic Heart Disease and Stroke in Korea

<Abstract> objectives: This study was conducted to estimate medical expenditure attributable to overweight and obesity in adults with ischemic heart disease and stroke using Korea National Health and Nutrition Examination survey data and Korea National Health Corporation data. methods : The medical expenditure of ischemic heart disease and stroke related to overweight and obesity were composed of inpatient care costs, outpatient care costs and medication costs. The population attributable risk (PAR) of overweight and obesity was calculated from national representative data of Korea such as the National Health Insurance Corporation cohort data and 2005 Korea National Health and Nutrition Examination survey data. results: The medical expenditure attributable to overweight and obesity of ischemic heart disease were 97.4 billion won(74.1-122 billion won). and stroke were 64.6 billion won(33.1-98.1 billion won). Consequently, these costs corresponded to 11.4% of total medical expenditure due to ischemic heart disease and stroke. conclusion: We conclude that overweight and obesity have increased medical expenditure from ischemic heart disease and stroke in Korea. These findings provide important support for implementing overweight and obesity management strategies in Korea.
Wake-on-WLAN

In bridging the digital divide, two important criteria are cost-effectiveness, and power optimization. While 802.11 is cost-effective and is being used in several installations in the developing world, typical system configurations are not really power efficient. In this paper, we propose a novel "Wake-on-WLAN" mechanism for coarse-grained, on-demand power on/off of the networking equipment at a remote site. The novelty also lies in our implementation of a prototype system using low-power 802.15. 4-based sensor motes. We describe the prototype, as well as its evaluation on field in a WiFi testbed. Preliminary estimates indicate that the proposed mechanism can save significant power in typical rural networking settings.
Laparoskopik bariatrik cerrahide anestezi yönetimi: 3 yıllık uygulamada perioperatif komplikasyonlar ve sonuçlar

Amac: Bu calismada, bariatrik cerrahi operasyonu geciren hastalarin perioperatif ve postoperatif sonuclarinin degerlendirilmesi amaclanmistir. Yontemler: Onam alindiktan sonra, retrospektif tasarlanan gozlemsel calisma yapildi. Ocak 2011 ve Mayis 2013 yillari arasinda laparoskopik gastrik plikasyon, sleeve gastrektomi ve roux-en-Y anastomoz operasyonlari geciren tum yetiskin hastalar calismaya dâhil edildi. Bulgular: Calisma suresince toplam 104 hasta dâhil edildi ve bunlarin; 49 (%47.1)'u laparoskopik roux-en-Y anastomoz, 44 (%42.3)'u laparoskopik gastrik plikasyon, ve 11 (%10.6)'i laparoskopik gastrik plikasyon idi. Yapilan calismada %1.9 mortalite orani (n = 2, roux-en-Y anastomoz operayonundan sonra bir vaka, ve gastrik plikasyon operasyonundan sonra bir vaka) saptanmistir. Sonuc: Calismada belirtilen bariatrik cerrahi prosedurlerinde, morbidite ve mortalite ile anestezi metodu ve yaklasimi arasinda bir iliski yoktur.
2-[(4-Chlorobenzyl)sulfanyl]-4-(2-methylpropyl)-6-[3-(trifluoromethyl)anilino]pyrimidine-5-carbonitrile

Three independent molecules comprise the asymmetric unit of the title compound, C23H20ClF3N4S. The conformations of the molecules are similar with the chlorobenzene and CF3-benzene rings almost perpendicular to, and almost co-planar with, the pyrimidinyl ring [range of dihedral angles = 80.36 (13)–88.07 (14) and 11.89 (14)–23.30 (14)°, respectively]; the benzene rings are roughly orthogonal to each other [64.81 (16)–72.16 (15)°]. In the crystal, two of the independent molecules associate via weak N—H⋯N(cyano) hydrogen bonds and 12-membered {⋯HNC3N}2 synthons; the third independent molecule self-associates similarly but about a centre of inversion. The sample studied was found to be a non-merohedral twin and the minor twin component refined to 47.16 (7)%.