Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploring universal phonological preferences: beyond articulation.

grammatical source. Summarizing, then, this dissertation examined whether the restrictions on syllable structure reflect abstract linguistic knowledge, or whether they are embodied in sensory and motor constraints. Contrary to the sensory embodiment account, we found that the effect of syllable structure obtains irrespective of stimulus modality (auditory or printed materials), and it is inexplicable by either phonetic cues or the orthographic similarity of the materials to English words. 9 In Experiment 3, onset type did not interact with other experimental factors. In Experiment 4, although there was a 3-way (suppression x onset type x list) interaction, the effect of onset type among the obstruent onsets was virtually identical in either suppression conditions. This higher order interaction in Experiment 4, then, was mostly likely due to the lbif-type syllables that were not presented in the regression analyses. Therefore, we conducted the regression analyses across suppression conditions in both experiments. 65 Table 7. The unique effect of (A) statistical properties (number of orthographic neighbors, neighbors’ frequency, bigram count and frequency of the whole word); and (B) onset type in step-wise regression analyses in Experiments 3-4. Data is comprised of d' responses to the obstruent-initial syllables (e.g., blif, bnif, bdif). Our results do not support the articulatory embodiment account either. We found that articulatory suppression clearly impaired participants’ overall performance, a finding that could reflect the contribution of articulatory simulation to perception. Critically, Experiment Condition Step Predictor ∆ R ∆ F df P value (†-p<0.1; *-p<0.05; **-p<0.01; ***-p<0.001) Suppression 1 onset type 0.074 6.588 1, 82 0.012 2 statistical properties 0.048 1.067 4, 78 0.379 1 statistical properties 0.062 1.315 4, 79 0.06 5.33 1, 78 5.46 1, 78 0.022 0.024 onset type 0.074 7.204 1, 78 0.009 4 Across Suppression Conditions 1 onset type 0.165 16.169 1, 82 0 2 statistical properties 0.037 0.902 4, 78 0.467 1 statistical properties 0.128 2.896 4, 79 0.027
The CARMENES Search for Exoplanets around M Dwarfs: A Low-mass Planet in the Temperate Zone of the Nearby K2-18

K2-18 is a nearby M2.5 dwarf, located at 34 pc and hosting a transiting planet that was first discovered by the K2 mission and later confirmed with Spitzer Space Telescope observations. With a radius of ∼2 R⊕ and an orbital period of ∼33 days, the planet lies in the temperate zone of its host star and receives stellar irradiation similar to that of Earth. Here we perform radial velocity follow-up observations with the visual channel of CARMENES with the goal of determining the mass and density of the planet. We measure a planetary semi-amplitude of Kb ∼ 3.5 and a mass of Mb ∼ 9 M⊕, yielding a bulk density around . This indicates a low-mass planet with a composition consistent with a solid core and a volatile-rich envelope. A signal at 9 days was recently reported using radial velocity measurements taken with the HARPS spectrograph. This was interpreted as being due to a second planet. We see a weaker, time- and wavelength-dependent signal in the CARMENES data set and thus favor stellar activity for its origin. K2-18 b joins the growing group of low-mass planets detected in the temperate zone of M dwarfs. The brightness of the host star in the near-infrared makes the system a good target for detailed atmospheric studies with the James Webb Space Telescope.
Different Chromosome-based Evolutionary Approaches for the Permutation Flow Shop Problem

This paper proposes approaches for adapting chromosome-based evolutionary methods to the Permutation Flow Shop Problem. Two types of individual representation (i.e. encoding methods) are proposed, which are applied on three different chromosome based evolutionary techniques, namely the Genetic Algorithm, the Bacterial Evolutionary Algorithm and the Particle Swarm Optimization method. Both representations are applied on the two former methods, whereas one of them is used for the latter optimization technique. Each mentioned algorithm is involved without and with local search steps as one of its evolutionary operators. Since the evolutionary operators of each technique are established according to the applied representation, this paper deals with a total number of ten different chromosome-based evolutionary methods. The obtained techniques are evaluated via simulation runs carried out on the well-known Taillard's benchmark problem set. Based on the experimental results the approaches for adapting chromosome based evolutionary methods are compared to each other.
The Promise of Biological and Molecular-orientated Treatments for Colon Cancer

After the acceptance of irinotecanand oxaliplatin-based combination therapies as a standard of care, treatment options now extend beyond conventional chemotherapy and routinely include biological agents targeting angiogenesis and the epidermal growth factor receptor (EGFR) system (bevacizumab [BEV] and cetuximab [CET]). The addition of BEV and CET to chemotherapy in the treatment of metastatic colorectal cancer (MCRC) has resulted in an increase in progressionfree survival (PFS) and overall survival (OS). 1
The co-existence of hot and cold gas in debris discs (Corrigendum)

Context. Debris discs have often been described as gas-poor discs as the gas-to-dust ratio is expected to be considerably lower than in primordial, protoplanetary discs. However, recent observations have confirmed the presence of a non-negligible amount of cold gas in the circumstellar (CS) debris discs around young main-sequence stars. This cold gas has been suggested to be related to the outgassing of planetesimals and cometary-like objects. Aims. The goal of this paper is to investigate the presence of hot gas in the immediate surroundings of the cold-gas-bearing debris-disc central stars. Methods. High-resolution optical spectra of all currently known cold-gas-bearing debris-disc systems, with the exception of β Pic and Fomalhaut, have been obtained from La Palma (Spain), La Silla (Chile), and La Luz (Mexico) observatories. To verify the presence of hot gas around the sample of stars, we have analysed the Ca II H&K and the Na I D lines searching for non-photospheric absorptions of CS origin, usually attributed to cometary-like activity. Results. Narrow, stable Ca II and/or Na I absorption features have been detected superimposed to the photospheric lines in 10 out of the 15 observed cold-gas-bearing debris-disc stars. Features are found at the radial velocity of the stars, or slightly blue- or red-shifted, and/or at the velocity of the local interstellar medium (ISM). Some stars also present transient variable events or absorptions extended towards red wavelengths (red wings). These are the first detections of such Ca II features in 7 out of the 15 observed stars. Although an ISM origin cannot categorically be excluded, the results suggest that the stable and variable absorptions arise from relatively hot gas located in the CS close-in environment of the stars. This hot gas is detected in at least ~80%, of edge-on cold-gas-bearing debris discs, while in only ~10% of the discs seen close to face-on. We interpret this result as a geometrical effect, and suggest that the non-detection of hot gas absorptions in some face-on systems is due to the disc inclination and likely not to the absence of the hot-gas component. This gas is likely released in physical processes related in some way to the evaporation of exocomets, evaporation of dust grains, or grain-grain collisions close to the central star.
Description and phylogenetic analysis of the mitochondrial genome of Pseudobagrus ondon Shaw (Siluriformes; Bagridae)

Abstract Pseudobagrus ondon is a small benthopelagic freshwater species of family Bagridae. In the present study, the complete mitochondrial genome of P. Ondon has been determined, and phylogenetic analysis with another individual and closely related species are preformed. The complete mitochondrial genome of P. ondon was 16,534 bp in length, containing 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes and 2 non-coding regions: a control region (D-loop) and an L-strand replication origin (OL). It indicated that D-loop, ND1, ND2, ND4, ND5 and CYTB may be appropriate markers for studying population as well as conservation genetics.
The hot subdwarf B + white dwarf binary KPD 1930+2752 A supernova type Ia progenitor candidate ,,, †

Context. The nature of the progenitors of type Ia supernovae is still under debate. KPD 1930+2752 is one of the best SN Ia progenitor candidates known today. The object is a double degenerate system consisting of a subluminous B star (sdB) and a massive white dwarf (WD). Maxted et al. (2000) conclude that the system mass exceeds the Chandrasekhar mass. This conclusion, however, rests on the assumption that the sdB mass is 0.5 M� . However, recent binary population synthesis calculations suggest that the mass of an sdB star may range from 0.3 Mto more than 0.7 M� . Aims. It is therefore important to measure the mass of the sdB star simultaneously with that of the white dwarf. Since the rotation of the sdB star is tidally locked to the orbit, the inclination of the system can be constrained if the sdB radius and the projected rotational velocity can be measured with high precision. An analysis of the ellipsoidal variations in the light curve allows the constraints derived from spectroscopy to be tightened. Methods. We derived the mass-radius relation for the sdB star from a quantitative spectral analysis of 150 low-resolution spectra obtained with the Calar Alto 2.2 m telescope using metal-rich, line-blanketed LTE model atmospheres with and without NLTE line formation. The projected rotational velocity was determined for the first time from 200 high-resolution spectra obtained with the Keck I 10 m and with the ESO-VLT 8.2 m telescopes. In addition a reanalysis of the published light curve was performed. Results. The atmospheric and orbital parameters were measured with unprecedented accuracy. In particular the projected rotational velocity vrot sini = 92.3 ± 1. 5k m s −1 was determined. Assuming the companion to be a white dwarf, the mass of the sdB is limited between 0.45 Mand 0.64 Mand the corresponding total mass of the system ranges from 1.33 Mto 2.04 M� . This constrains the inclination to i > 68 ◦ . The photometric analysis allows the parameters to be constrained even more. A neutron star companion can be ruled out and the mass of the sdB is limited to the range between 0.45 Mand 0.52 M� . The total mass of the system ranges from 1.36 Mto 1.48 Mand hence is likely to exceed the Chandrasekhar mass. The inclination angle is 80 ◦ and the light curve shows weak and shallow signs of eclipses. A high-precision light curve is needed in order to accurately measure these eclipses. So KPD 1930+2752 qualifies as an excellent double degenerate supernova Ia progenitor candidate. Conclusions.
Physica A Quantitative assessment of increasing complexity

We study the build up of complexity on the example of 1 kg matter in different forms. We start with the simplest example of ideal gases, and then continue with more complex chemical, biological, life, social and technical structures. We assess the complexity of these systems quantitatively, based on their entropy. We present a method to attribute the same entropy to known physical systems and to complex organic molecules, up to a DNA molecule. The important steps in this program and the basic obstacles are discussed.
Developments in Business Simulation and Experiential Learning , Volume 34 , 2007 393 COMPUTER BUSINESS SIMULATION DESIGN : NOVELTY & COMPLEXITY ISSUES

Developing a business simulation is a time consuming, costly and potentially risky task. And, the risk of time and cost overrun is associated with the novelty and complexity of the simulation. This paper suggests the aspects of simulation novelty and complexity that are the sources of design risk and explores these in the context of a range of actual simulation designs so that designers can take action when forecasting costs, the development schedule and starting the design and development work. The areas of design novelty and difficulty are described and discussed in the context of five representative simulations. Following this the impacts on actual design difficulty and complexity are discussed and analyzed for the simulations. Finally, a design time model is proposed that empirically links model size with duration and novelty and design time with model size. In conclusion, the paper suggests that design time can be forecast from simulation duration provided the forecast is adjusted to take into account simulation novelty.
Hepatic stellate cells transmigration and remodeling are related to CCN3 in oxaliplatin-resistant hepatocellular carcinoma

Background: Hepatic stellate cells (HSCs) have a key role in fibrogenesis and in the filtrates of the hepatocellular carcinoma (HCC) stroma, in which they are remodeled and play a critical role in HCC progression. While, the precise mechanism associated with HSCs trending, infiltration and remodeling is still vague in HCC, especially in Oxaliplatin-resistant HCC. Materials and Methods: The chemoresistant cell and mouse model, and the HCC clinical samples were collected and were established. We explored the relationship between secretory CCN3 from Oxaliplatin-resistant HCC and the infiltration of HSCs in Oxaliplatin-resistant HCC microenvironment. We also evaluated the associated mechanism of HSCs infiltration and HSCs remodeling in HCC with high expression of CCN3. Results: We constructed oxaliplatin-resistant HCC models and found the increased infiltration of HSCs into the microenvironment. We reanalyzed the cDNA profiles of the oxaliplatin-resistant HCC and found CCN3 was one of the significantly increased genes. In HCC clinical samples, the levels of CCN3 and α-SMA are positively correlated, and high expression of CCN3 and α-SMA are positively associated with malignant phenotype and poor prognosis. Then we proved that CCN3 could enhance the migration and proliferation of HSC, and induce the remodeling of HSC with elevation of cytokines relating to HCC malignancy, which was related to ERK signaling pathway activation. Finally, we confirmed that the role of CCN3 enhanced the transmigration of HSCs using the xenograft tumor model. Conclusions: HSCs transmigration and remodeling are positively related to CCN3 paracrine in hepatocellular carcinoma, which orchestrated the stroma-derived resistance to chemotherapy in HCC.
Interface Phenomena and Interaction Energy at the Surface of Electroconductive Solids

For the local gradient approach in thermomechanics, the regularities of nearsurface nonhomogeneity in nonferromagnetic electroconductive solids, including the size effect of the ultimate stress limit are studied. It is noted that surface values of interaction energy and thermodynamic electric potential are determined by physical and geometrical properties of a body.
Facile preparation of N- and O-doped hollow carbon spheres derived from poly(o-phenylenediamine) for supercapacitors

Nitrogen and oxygen doped hollow carbon spheres (HCSs) have been prepared by pyrolysis of poly(o-phenylenediamine) (PoPD) submicrospheres, which were synthesized by a facile polymerization procedure with an environmental-friendly dopant glycine. Utilizing o-phenylenediamine (oPD) and glycine as the precursors, we are also motivated by the recognition that effective heteroatom doping increases the supercapacitor performance of carbon materials. The as-prepared N- and O- doped HCSs exhibit an enlarged specific surface area (∼355 m2 g−1) and pore volume (∼0.14 cm3 g−1), and they have superior performance in supercapacitors owing to the synergies gained from effective heteroatom doping, their hollow structures, and their good mesoporosity. The reasonable capacitance performance coupled with the facile synthesis procedure suggests supercapacitor applications.
Does the Corruption Perceptions Index Predict the Outcome of Competitions? Evidence from a Natural Experiment around the World

In this paper we study the effect of the corruption, as measured by the Corruption Perceptions Index (CPI), on the probability of determining the outcome in real competitive settings, where all agents in all countries are faced with exactly the same task under fixed and known rules. To that end we utilize data from soccer matches between a team in immediate danger of being relegated to a lower division and a team not affected by the results in the respective match. Based on analysis of a similar situation that occurred on the last day of a season in 75 different countries during the period between 2001 and 2013, we find that the CPI significantly correlated with the probability of achieving the desired result in order to avoid relegation to a lower division. The odds are significantly higher when the country is more corrupt according to the CPI. We also find strong evidence of a significant effect of the CPI on quid pro quo behavior that takes place in the later stages of the following year. Despite the fact that the CPI is a survey-based index and its effect is not linear throughout the scale of scores, we still find a significant association between CPI level and the results of sensitive soccer matches that were previously found to be infected by corruption. Our results provide evidence that the virus of corruption, as measured by the CPI, affects the level of competition in social activities that are not necessarily directly linked to governmental activities.
A dilemma of logic for the VA?

In this issue, Rosen and colleagues report on an exquisitely well-designed and well-implemented research effort to examine a strategy to improve outcomes for veterans with posttraumatic stress disorder (PTSD) after discharge from residential treatment. However, the aim of the study, although well intentioned, seems naïve given current realities, and it misses the mark in regard to lessons learned over the past 30 years about treatment outcomes for veterans with PTSD and the challenges that treatment presents.
Precision Livestock Farming: Precision feeding technologies and sustainable livestock production

In order to be able to produce safe, uniform, cheap, environmentally- and welfare-friendly food products and market these products in an increasingly complex international agricultural market, livestock producers must have access to timely production related information. Especially the information related to feeding/nutritional issues is important, as feeding related costs are always significant part of variables costs for all types of livestock production. Therefore, automating the collection, analysis and use of production related information on livestock farms will be essential for improving livestock productivity in the future. Electronically-controlled livestock production systems with an information and communication technology (ICT) focus are required to ensure that information is collected in a cost effective and timely manner and readily acted upon on farms. New electronic and ICT related technologies introduced on farms as part of Precision Livestock Farming (PLF) systems will facilitate livestock management methods that are more responsive to market signals. The PLF technologies encompass methods for electronically measuring the critical components of the production system that indicate the efficiency of resource use, interpreting the information captured and controlling processes to ensure optimum efficiency of both resource use and livestock productivity. These envisaged real-time monitoring and control systems could dramatically improve production efficiency of livestock enterprises. However, further research and development is required, as some of the components of PLF systems are in different stages of development. In addition, an overall strategy for the adoption and commercial exploitation of PLF systems needs to be developed in collaboration with private companies. This article outlines the potential role PLF can play in ensuring that the best possible management processes are implemented on farms to improve farm profitability, quality of products, welfare of livestock and sustainability of the farm environment, especially as it related to intensive livestock species.
Perspectives of Using of E-Nose System for Monitoring of Organic Compounds in WasteWater

Introduction In recent years, there has been an increasing interest in the issue of air and water quality, which leads to the urgency of development and improvement of environmental monitoring techniques [1]. This is of particular concern with regards to sewage, whose quality needs to be quickly assess after cleaning. In addition, the periodic or accidental discharges of chemical pollutants and toxic substances into the sewage system can have a negative impact on the bioprocesses associated with the treatment of wastewater [2]. Therefore, there is a great need to develop a suitable on-line monitoring system of the sewage and natural waters quality. For fast monitoring of water systems, real-time analysis methods should be used. Previous studies have shown that the electronic nose (e-nose) system is capable of detecting and recognizing various atmospheric odors [3-5], but a very small number of studies are conducted directly in the field [2, 6], in particular, to identify organic pollutants in various water systems. The aim of this article is a theoretical assessment of the promising use of e-nose for the determination of organic pollutants in sewage and natural waters.
GENETIC VARIABILITY OF THE VP 1 GENE OF BK AND JC POLYOMAVIRUSES IN HIV-INFECTED PATIENTS

Human polyomaviruses, BK virus (BKV) and JC virus (JCV), are world widely distributed in human population. After primary infection, BKV and JCV establish latency in kidneys and upper part of urinary tract. In seropositive healthy individuals asymptomatic reactivation of both viruses occurs in in 0.5-20%. On the other hand, reactivation of these viruses in imunosuppressed patients, primarily in patients with T cell immunodeficiency, can lead to development of polyomavirus-associated diseases. Some of these diseases such as progressive multifocal leukoencephalopathy (PML), polyomavirusinduced nephropathy (PVN), hemorrhagic cystitis (HC) are life-threatening diseases with high mortality and morbidity rate. However, they do not affect all immunosuppressed patients, suggesting that other factors, such as genetic variability of BKV and JCV, can contribute to their occurrence. Immunosuppression leads to increased levels of replication of both viruses. Increased levels of replication are associated with higher incidence of mutations in the VP1 gene. Mutations, especially those located in outer loops, may lead to changed tropism and generation of more aggressive variants of BKV and JCV. This review is focused on clinical significance of BK and JC virus infection in immunosuppressed patients, especially in HIV-infected, and sequence changes in the VP1 gene that can contribute to selection of more virulent variants of BKV and JCV via adaptive evolution.
Design of a Low Phase Noise VCO Used for LTE Band40

According to the frequency of LTE Band40 from 2300MHz to 2400MHz using for 4G mobile communication distributed by Ministry of Industry and Information Technology of China, a low phase noise, small size and low power consumption voltage-controlled oscillator (VCO) which can be used in mobile phones supporting 4G LTE mode is designed. The VCO based on a modified Clapp circuit topology is analyzed with the negative resistance analysis method and simulated in the time domain and frequency domain, respectively. Finally, the actual circuit is fabricated and tested. The test results show that the size of the VCO is 11mm by 9mm, the phase noises of the VCO are -53.79dBc/Hz@300Hz and -67.42dBc/Hz@1KHz, the voltage-controlled tuning sensitivity is about 24.4MHz/V which results in an operating frequency range from 2294MHz to 2416MHz up to 5V reverse bias voltage of the varactor and the output power is about 1dBm, meeting the application requirements of the 4G mobile communication well.