Miracle-dz/UniFAR-FTUs huggingface dataset:
On the Capacity of a Process with Batch Processing and Setup Times

While batch processes are ubiquitous across industries, there is little understanding of the determination of the capacity (i.e., the maximum long‐term output rate) of such processes. In this study, we consider processes with collaboration (activities may require multiple resources simultaneously) and multitasking (the same resource may be needed for multiple activities), and characterize the capacity of an arbitrary deterministic, single‐product process with batch processing and (activity) setup times. Such a process can be viewed as an “intermittent” process in which production occurs in discrete quantities; specifically, in multiples of the batch size. To obtain a corresponding “smooth” process, we use the most natural transformation that eliminates batching and setups, and simply prorates the processing and setup time per flow unit. The main result of our analysis is that capacity remains unaffected in this transformation. Then, using recent developments in the literature on process capacity, the capacity of the transformed process can be obtained by computing the fractional chromatic number of an associated graph—this latter problem can be formulated as a linear program.
HYGIENIC ANALYSIS OF FLUORIDE CONTENT IN DRINKING WATER IN SOME SETTLEMENTS OF THE REPUBLIC OF MOLDOVA

Objectives. The increased fluoride content in drinking water sources, in many settlements of the Republic of Moldova, indicates an endemic situation in the country. In settlements where fluoride exceeds the normative limit, the population suffers from dental fluorosis and osteofluorosis, affecting also the endocrine and nervous systems. The aim of the paper is to analyze the fluoride content in drinking water sources and highlight the endemic fluorosis districts in the Republic. Materials and methods. A descriptive epidemiological study of prevalence was performed. Data were presented by arithmetic means (M) ± standard deviation (m). The data of the fluoride content, taken from the registers of the sanitary-hygienic laboratories of the Public Health Centers, during the years 2010-2017 were processed and analyzed. The following districts were selected: Ungheni, Rișcani, Ceadir-Lunga, Edineț, Orhei, Fălești, Ștefan Vodă, water samples were taken from decentralized sources. Results. Analyzing the water samples, the following fluoride values ​​were detected in different districts of the republic: Ungheni – 1.97 ± 0.05 mg / l (min – 1.6; max – 4.4); Riscani – 0.72 ± 0.02 (0.01; 4.0); Ceadâr-Lunga – 1.13 ± 0.06 (0.05; 9.4); Edineț – 0.81 ± 0.01 (1.6; 4.4); Orhei – 0.75 ± 0.01 (0.05; 2.2); Fălești – 0.99 ± 0.05 (0.09; 16.2); Ștefan Vodă – 1.44 ± 0.06 (0.02; 8.5). The maximum fluoride limit was exceeded in all districts surveyed. Conclusions. In the Republic of Moldova there are districts where the fluoride concentration essentially exceeds the normative limit. Increased concentrations are observed in the average values ​​of the water samples, and in the unitary ones.
Comparison of prophylactic levosimendan versus intra-aortic balloon pump for off-pump coronary artery bypass grafting in patients with low ejection fraction: A randomized-controlled trial

Objectives: This study aims to compare the efficacy and short-term clinical outcomes of levosimendan versus intra-aortic balloon pump (IABP) in patients undergoing off-pump coronary artery bypass grafting (OPCABG). Patients and methods: This prospective, randomized-controlled study included a total of 60 patients (44 males, 16 females; mean age 60.58+5.23 years; range, 42 to 70 years) with low left ventricular ejection fraction (<25%) undergoing OPCABG between January 2019 and September 2019. The patients were divided into two groups as levosimendan (Group L) and IABP (Group B). Hemodynamic parameters were measured at prespecified time points. Results: Hemodynamic data recorded at baseline were comparable in both groups, while cardiac index progressively increased in both groups. Although, the increase was statistically significant on multiple measures analysis of variance in both groups, no significant difference was observed at different time points. Pulmonary capillary wedge pressure decreased in both groups; however, the decline was not statistically significant. Serum lactate concentration was consistently lower in Group B compared to Group L at all time points. The heart rate, mean arterial pressure, and Vasoactive Inotropic Score (VIS) were comparable in both groups at all time points. The mean length of intensive care unit (ICU) stay was statistically significant in Group B compared to Group L. Conclusion: The use of prophylactic levosimendan is comparable to prophylactic IABP, when hemodynamic parameters are considered. Prophylactic levosimendan is associated with a shorter length of hospital and ICU stay. Prophylactic levosimendan can be considered an alternative to prophylactic IABP in patients with low ejection fraction in whom IABP is contraindicated.
Hisse Senedi Getirileri Üzerinde Para ve Maliye Politikası Araçlarının Etkisi: Borsa İstanbul Üzerine Bir Araştırma

Arastirmada Turkiye’de uygulanan para ve maliye politikalarinin Borsa Istanbul’da islem goren hisselerin getirilerine etkisi incelenmistir. Calismada bagimsiz degiskenler olarak para politikasini olcmek icin M3 para arzi / GSYH, maliye politikasini olcmek icin ise faiz disi butce dengesi / GSYH degiskenleri kullanilmistir. Bagimli degisken olarak ise Borsa Istanbul’un performansini olcmek icin BIST100 endeksinin getirisi belirlenmistir. Ceyreklik donem araliginin kullanildigi veri setinde 2016.1C ve 2019.3C arasindaki zaman dilimi kapsanmistir. Calismada duraganligin tespiti icin ADF birim kok testi, degiskenler arasindaki iliskinin ve gecikme surelerinin tespiti icin ARDL sinir testi ve hata duzeltme modeli (ECM), yapisal kirilmalarin sonuclara etki edip etmedigini anlamak icin ise CUSUM ve CUSUM x2 testleri uygulanmistir. Arastirma bulgularina gore butce dengesindeki negatif yonlu degisimler ve M3 para arzindaki artis istatistiksel olarak anlamli bir sekilde BIST100 endeksi uzerinde pozitif etkiye sahiptir.
Anteseden dan Konsekuensi dari Perceived Trustworthiness Pada Produk Jersey Tim Sepakbola di Online Shop Kaskus

The objectives of this research was analyzed the effect of behavioral attitude, the effect of cognitive perception, the effect of perceived security, the effect of perceived privacy and the effect of perceived trustworthiness. A sampling with purposive sampling techniques of a man who use original or non original jersey as the respondents provided the data that were analyzed for this study. Using a sub-set of the sample consisting of a man who use original or non original jersey was used to test six hypothesized relationships in the model. Data analysis in this research was used structural equation modelling (SEM) to test the independent variables influence the dependent variable. The result of this research conclude that the effect of positively and significantly perceived trustworthiness towards purchase behavior customer of online shop product in social media kaskus. Abstrak Tujuan dari penelitian ini adalah menganalisis pengaruh sikap perilaku, pengaruh persepsi kognitif, pengaruh keamanan yang dirasakan, pengaruh privasi yang dirasakan dan pengaruh persepsi kepercayaan.Pengambilan sampel dengan teknik purposive sampling dari seorang pria yang menggunakan kaus asli atau tidak asli sebagai responden memberikan data yang dianalisis untuk penelitian ini. Menggunakan sub-set sampel yang terdiri dari seorang pria yang menggunakan jersey asli atau tidak asli digunakan untuk menguji enam hubungan hipotesis dalam model. Analisis data dalam penelitian ini menggunakan pemodelan persamaan struktural (SEM) untuk menguji pengaruh variabel independen terhadap variabel dependen.Hasil penelitian ini menyimpulkan bahwa pengaruh kepercayaan yang dirasakan secara positif dan signifikan terhadap perilaku pembelian pelanggan produk toko online di media sosial. kaskus. Kata Kunci : Sikap Prilaku, Persepsi Kognitif, keamanan, Privasi, Kepercayaan
Characteristics of power output during supramaximal cycle ergometer exercise in first- and third-grade male Japanese high school cyclists

Purpose: The purpose of this cross-sectional study was to clarify if there are differences in optimal load (Lopt; force factor), optimal cadence (Copt; velocity factor), and maximal anaerobic power (MAnP) between first- and third-grade high school cyclists and if Lopt is related to muscle strength.Methods: Forty-three male high school cyclists (first grade: 15.6 ± 0.5 years, n = 20; third grade: 17.3 ± 0.5, n = 23) participated in this study. The MAnP test was conducted at three different loads using an electrically braked cycle ergometer, and MAnP, Lopt, and Copt were determined. The subjects’ isokinetic knee extensor and flexor muscle strengths were measured at 180°/sec in an isokinetic dynamometer.Results: The MAnP value of the third-grade cyclists was significantly higher than that of the first-grade cyclists (1116.2 ± 131.8 vs. 946.6 ± 106.5 W, P < 0.01). There was no difference in Copt between the two grades, whereas Lopt was significantly higher in third-grade cyclists than first-grade cyclists (9.4 ± 0.8 vs. 8.2 ± 0.7 kp, P < 0.01). Both muscle strengths were significantly higher in third-grade cyclists than first-grade cyclists. In all subjects, muscle strengths were significantly correlated with Lopt (knee extension and flexion; r = 0.670 and r = 0.466, respectively, P < 0.01). Conclusion: The higher MAnP resulting from greater Lopt in third-grade high school cyclists was related to greater lower limb muscle strength, compared with that of first-grade high school cyclists.
A Educação Infantil na Pandemia: a experiência de uma escola pública antirracista

projeto didático e, fim, temporária consolidação. Ao narrar discutir esse processo marcado por reflexões críticas, aprendizados e mudanças, o artigo pretende contribuir para o debate sobre concepções e práticas na educação infantil, das quais trabalho remoto emergencial apenas reflexo. Abstract This article is part of a research on the political-pedagogical project of a municipal school for early childhood education that adopts ethnic-racial relations as one of its main pillars. It presents a case study about the work developed remotely by the school unit during the closure forced by the COVID-19 pandemic. It analyzes the possibilities and limits to implement, in this context, an antiracist curriculum, focused on ludicity and affectivity; it also discusses the challenges to include all children in the process and to guarantee the right to education. The sources of the study were the initiatives documented in the social networks, interviews and a survey carried out by the school. The analysis is made along a narrative, identifying four phases in the development of the remote work: the maintenance of the bond with the children, the reorganization of the initiatives, the elaboration of a didactic project and, finally, the temporary consolidation. By reporting and discussing this process marked by critical reflections, learning and changes, the article intends to contribute to the debate on conceptions and practices in early childhood education, of which remote emergency work is only a reflex.
Identification of key genes in breast cancer cell line under hypoxia condition: A bioinformatics analysis

Introduction:The present study attempted to investigate the key pathways and genes which are associated with hypoxia in the human breast carcinoma cell line MDA-MB-231 with searched in gene expression omnibus (GEO) database for mRNA microarray data of MDA-MB-231 in normal and hypoxia condition. Methods: Three GEO datasets GSE37340, GSE39042, and GSE42416 were downloaded from the Gene Expression Omnibus (GEO) database that these GEO profiles have of 9 cell lines in hypoxia condition and eight cell lines in normal condition. The differentially expressed genes (DEGs) between MDA-MB-231 cell line in hypoxia and normal condition were analyzed by Geo2R software. Next, all the differentially expressed genes (DEGs) with p<0.05 and fold change ≥1 or ≤-1 was identified. Among all the differentially expressed genes, only 32 genes were at least in two datasets (31 up regulated and 1 down regulated) after gene integration. Moreover, DEGs ontology terms, Kyoto Encyclopedia and Genomes pathways were analyzed using EnrichR database. Subsequently, a protein-protein interaction network was constructed using STRING and MCODE software. Finally, the survival analyses performed with Kaplan Meier-plotter (KM) online dataset. Results: Thirty-two genes were found to be at least two datasets (i.e., SLC2A3, BNIP3, ENO2, PFKFB3, PLOD2, SLC2A1, HK2, ADM, etc.) that two genes among up regulated genes (HK2, ADM) were expressed in all three datasets. Conclusion: These identified genes and pathways could help to understand the mechanism of development of (Triple-negative breast cancer) TNBC under hypoxia condition. Also HK2, ADM, CENP family, might be promising targets for the TNBC treatment.
TREM2 Levels Are Increased in Neurodegenerative Disease Patients and in an Alzheimer's Disease Mouse Model

Background: Triggering receptor expressed on myeloid cells 2 (TREM2) is expressed on microglia, and it plays an important role in neurodegenerative diseases, especially Alzheimer’s disease (AD). This study aimed to elucidate the potential value of TREM2 as biomarker for the diagnosis of AD.Methods: Serum TREM2 levels in human subjects and mice were detected by ELISA. TREM2 mRNA and protein expressions in leukocytes and mouse brain tissues were detected using real-time quantitative PCR(RT-qPCR) and western blot analysis. The cognitive ability of patients was measured by MMSE/MoCA score. The cognitive ability of mice was evaluated by the Morris water maze (MWM) test.Results: Our results showed that the serum concentration and expression levels of TREM2 in leukocytes were increased both in neurodegenerative patients and in an AD model mice.TREM2 expression was correlated with the cognitive impairment in AD patients and APP/PS1 mice.Conclusion: This study indicates that TREM2 is a novel potential biomarker for AD diagnosis.
Atomic Adsorption on Nitrogenated Holey Graphene

Two-dimensional (2D) crystals with C2N stoichiometry have recently been synthesized. This novel material, dubbed nitrogenated holey graphene (NHG), is a semiconductor unlike pristine graphene. For any novel material, it is fundamental to understand the behaviors of different adatoms on its surface, a process responsible for a rich phenomenology. In this work, we employed first-principles calculations and a hybrid quantum mechanics/molecular mechanics method to investigate the adsorption of H, B, and O on NHG sheets. The adsorption of H atoms could prove important for applications in hydrogen storage and gas sensors, whereas the adsorption of O in any new material is important to understand its oxidation process. Both N and B are common dopants in carbon-based systems, such as in BNC structures. We found that H and B prefer to adsorb on top of a nitrogen atom, whereas O prefers to adsorb on top of a carbon–carbon bond. The electronic structure of NHG also changes as a result of the presence of adatoms, wit.
Le financement du secteur de l’artisanat via le contrat financier Salam : cas de la ville de Marrakech

Dans un contexte marque par la marginalisation du secteur artisanal par le systeme bancaire classique et l’avenement recent des banques participatives au Maroc, ce travail cherche a detecter les attentes des entreprises artisanales vis-a-vis de l’instrument financier islamique Salam en matiere du financement des besoins du secteur. La fragilite d’un tel secteur et son caractere informel, dans la plupart des cas, peuvent etre surmontes financierement par ces nouvelles banques, d’ou la necessite de decouvrir l’utilite du contrat Salam pour l’artisanat. En se basant sur l’analyse factorielle de correspondances multiples, il s’est avere que le contrat Salam repond, a la fois, aux besoins de commercialisation et a ceux correspondant au financement pour l’echantillon selectionne au sein de la ville de Marrakech. La majeure partie des interviewes avance l’adaptabilite de ce contrat avec les besoins de leur activite artisanale.
Cost-Effective Active Semi-Supervised Learning on Multivariate Time Series Data With Crowds

Traditional active learning algorithms have several limitations: 1) they cannot obtain satisfactory results on high dimensional datasets, especially for multivariate time series (MTS) data; 2) traditional crowd-based labeling approaches do not consider the swarm intelligence of crowds, which cannot guarantee the confidence of labeling results; and 3) up to now, few works have addressed the issue of tradeoff between the labeling accuracy and the labeling cost with crowdsourcing labelers. There is also a lack of research on crowd-based active learning on MTS data. To efficiently address the above issues, we propose a new framework of active semi-supervised learning. First, two criteria are advanced to measure the importance of an unlabeled sample from different perspectives. A dynamic time wrapping (DTW)-based similarity matrix is used to represent the MTS data. Next, to confidently label the most valuable samples with minimum cost, we advance a cost-effective crowd selection model and an adaptive labeler selection approach (ALS) to select the most suitable labelers, which could minimize the total cost of labeling and achieve better classification performance. Experiments on ten datasets show the effectiveness of our proposed methods.
Optical response functions of selected gold-cluster thiolates

A set of broad-range NIR-vis-UV optical absorption spectra, measured for selected gold-cluster thiolate compounds (GCTs, containing ∼20 to 300 Au atoms), is consistently displayed and then analyzed within the dielectric-functions approach. The size-evolution toward 'bulk' (Au diameter > 3-nm) optical response is thereby clearly demonstrated. The emergence of apparent energy gaps, Eon, for onset of optical absorption, as well as other fine-structure, is consistent with that of a well-quantized metallic electronic structure for the compounds' cores: the onset-band's location Eon and intensity are attributed semiclas- sically to a circulation-frequency resonance of the Fermi-level electrons. With decreasing cluster-size, an increasing fraction of the integrated (sum-rule) intensity is 'missing' from the < 4 eV region. This might be explained by the outermost layer consisting of Au(I)thiolate complexes.
Automatic License Plate Recognition: An Efficient and Layout-Independent System Based on the YOLO Detector

Automatic License Plate Recognition (ALPR) has been a frequent topic of research due to many practical applications, such as border control and traffic law enforcement. This work presents an efficient, robust and layout-independent ALPR system based on the YOLO object detector that contains a unified approach for license plate detection and layout classification and that leverages post-processing rules in the recognition stage to eliminate a major shortcoming of existing ALPR systems (being layout dependent). We also introduce a publicly available dataset for ALPR, called UFPR-ALPR, that has become very popular, having been downloaded more than 650 times by researchers from 80 different countries over the past two years. The proposed system, which performs in real time even when there are 4 vehicles in the scene, outperformed both previous works and commercial systems on four public datasets widely used in the literature. The entire ALPR system (i.e., the architectures and weights), along with all annotations made by us are publicly available at https://web.inf. ufpr.br/vri/publications/layout-independent-alpr/.
Graphene Oxides Derivatives Prepared by an Electrochemical Approach

: Graphene oxide (GO) is a novel material that can be defined as a single monolayer of graphite with oxygen-containing functionalities such as epoxides, alcohols, and carboxylic acids. It is an interesting alternative to graphene for many applications due to its exceptional optical, chemical, and electrical properties. In this study, GOs with different extent of surface groups were prepared by an electrochemical two-stage approach using graphite as raw material. Various synthesis conditions were tested to increase the nanomaterial oxidation level, and the surface topography of the GO derivatives was analyzed via Scanning Electron Microscopy (SEM) and atomic force microscopy (AFM). The electrochemical approach employed in this study maintains the integrity of the graphene sheets, allowing to get large, uniform and well exfoliated GO. A correlation was found between the derivatives properties and their surface topography, interlayer spacing, defect content and specific surface area (SSA). In particular, the electrical resistance decreases with increasing SSA while rises with increasing the D/G band intensity ratio in the Raman spectra, hence the defect content. Understanding the structure-property relationships in these materials is useful for the design of modified GOs with controlable morphologies and properties for a wide range of applications in electrical/electronic devices.
Antibiotic and non-antibiotic treatment of urinary tract infections in the era of growing antimicrobial resistance

Urinary tract infection is one of the most common indications for prescribing antibiotics among otherwise healthy patients. The lifetime risk of having urinary tract infection among the female population reaches up to 50%. Empirical antibiotic therapy is the first line of treatment in uncomplicated cases. Bacterial resistant to antibiotics is constantly increasing and it is resulting in the evolvement of multidrug-resistant pathogens but also causes a limitation in empirical treatment options. Due to growing antimicrobial resistance, local antimicrobial susceptibility patterns should always be considered especially when empirical treatment is introduced. The article shows the ongoing need for updates in local resistance patterns. Recommendations for the empirical treatment should be constantly verified with reference to the local antimicrobial resistance status. Non-antibiotic preparations may be useful only in the prevention of urinary tract infections.