Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploring software-defined radio on Multi-Processor System-on-Chip

Sofware-Defined Radio (SDR) has been proposed as a solution for a single device to overcome various and changing radio standards. It allows wide range of computational device, such as personal computer processor and Multi-Processor System-on-Chip (MPSoC) to function as radio baseband processor. Number of works of SDR implementation on MPSoC has been done, variously differing according to underlying hardware platform. Main reason is to utilize the hardware architecture, providing power efficiency and effective processing. This paper explores idea of utilizing RUMPS401 chip, an ARM based heterogeneous MPSoC designed by Universiti Tunku Abdul Rahman VLSI Center, as a baseband processor based on its architecture. A workflow of implementing SDR on ARM based MPSoC using Matlab and ARM Keil Development Tools is also proposed here. The implementation and testing of the proposed idea is still an ongoing work.
A case control study of suicides in China with and without mental disorder.

BACKGROUND Chinese suicide samples have provided opportunities to study the differences between suicides with and without psychiatric diagnoses. AIMS To examine the differences between suicides with and without mental disorders. METHODS Sixty-six suicides and 66 living controls were studied with psychological autopsy interviews in rural China. Those who died by suicide with (n = 45) and without (n = 21) mental disorders were compared on demographic characteristics, suicidal behavior, social support, life events, and depressive symptoms (as measured by the Hamilton Depression Rating Scale, HAMD). RESULTS Suicides with and without psychiatric diagnoses had significant differences in many demographic and social factors. In comparison with suicides with psychiatric diagnoses, suicides without psychiatric diagnoses were younger, were better educated, had higher income, were more likely to kill themselves using pesticides or other poisons, were less likely to have a history of prior suicide attempt, had less long-term life events and more recent life events, and scored lower on HAMD. CONCLUSIONS These two groups might be from two different populations. This finding has important implications for more effective and targeted suicide prevention strategies in China.
Enhanced Vasodilatory Responses to Milrinone in Catecholamine-Precontracted Small Pulmonary Arteries

β-Adrenergic agonists (e.g., epinephrine [E] and norepinephrine [NE]) and phosphodiesterase-III inhibitors (e.g., milrinone) are often used in combination to augment ventricular function in the perioperative period. In the myocardium, milrinone acts synergistically with β-adrenergic agonists to increase contractility. However, the potential interaction between catecholamines with combined α- and β-adrenergic activity and milrinone in the pulmonary circulation has not been determined. We evaluated the vasodilatory effects of milrinone and nitroglycerine on large elastic and small muscular porcine pulmonary vascular rings precontracted with catecholamines with β-adrenergic agonist activity (E and NE), the α-adrenergic agonist phenylephrine, and a nonadrenergic agonist, the thromboxane analog U46619. In small pulmonary arteries, the vasorelaxation with milrinone was significantly enhanced in rings precontracted with E or NE compared with those precontracted with phenylephrine or U46619. However, in large pulmonary arteries, the vasorelaxation with milrinone was similar in all vessel rings and was not influenced by the agonist used to induce precontraction. In marked contrast, the vasorelaxant responses to nitroglycerine were not altered by the specific agonist used for precontraction in either small or large pulmonary vascular rings. Thus, the pulmonary vascular effects of milrinone are enhanced when combined with drugs with β-adrenoreceptor agonist activity. The vasodilatory interactions exhibited by phosphodiesterase-III inhibitors and the catecholamines NE and E suggest that their combined use might be beneficial in circumstances in which ventricular dysfunction and increased pulmonary vascular resistance occur.
Understanding parasitic effects to improve the “3ω” measurement of GaN HEMTs thermal impedance

The thermal impedance of Gallium Nitride based High Electron Mobility Transistors (GaN HEMTs) has been characterized using the “3ω method”. The method was initially proposed by D.G. Cahill to measure the thermal conductivity of bulk materials or layers. We already demonstrated in a previous work that under certain conditions the voltage oscillation at the third harmonic is the real image of the thermal impedance of the device in the frequency domain. In this work, we propose both a theoretical approach to understand the limitation of our 3ω test bench and a comparison with measurements.
MAXIMIZING THE DETECTION PROBABILITY OF KILONOVAE ASSOCIATED WITH GRAVITATIONAL WAVE OBSERVATIONS

Estimates of the source sky location for gravitational wave signals are likely to span areas of up to hundreds of square degrees or more, making it very challenging for most telescopes to search for counterpart signals in the electromagnetic spectrum. To boost the chance of successfully observing such counterparts, we have developed an algorithm that optimizes the number of observing fields and their corresponding time allocations by maximizing the detection probability. As a proof-of-concept demonstration, we optimize follow-up observations targeting kilonovae using telescopes including the CTIO-Dark Energy Camera, Subaru-HyperSuprimeCam, Pan-STARRS, and the Palomar Transient Factory. We consider three simulated gravitational wave events with 90% credible error regions spanning areas from ∼ 30 deg 2 to ∼ 300 deg 2 . Assuming a source at 200 Mpc , we demonstrate that to obtain a maximum detection probability, there is an optimized number of fields for any particular event that a telescope should observe. To inform future telescope design studies, we present the maximum detection probability and corresponding number of observing fields for a combination of limiting magnitudes and fields of view over a range of parameters. We show that for large gravitational wave error regions, telescope sensitivity rather than field of view is the dominating factor in maximizing the detection probability.
A new biochemical marker for joint injury. Analysis of YKL-40 in serum and synovial fluid.

We report the development of the first radioimmunoassay for YKL-40, a M(r) = 40 kDa protein which is secreted at high levels by human synovial cells and articular cartilage chondrocytes, and by the human osteosarcoma cell line MG63. This assay uses YKL-40 purified from the conditioned medium of MG63 cells as standard and tracer, and as antigen for immunizing rabbits. With this assay we have discovered high levels of YKL-40 antigen in serum and SF. The molecular weight of serum and SF YKL-40 is identical to purified YKL-40. To evaluate the possible utility of YKL-40 in the assessment of joint disease, we measured YKL-40 in serum and SF of 49 patients with various forms of inflammatory and degenerative joint disease and in the serum of 50 normal adults. The YKL-40 level in serum was significantly higher (P < 0.001) in the patients compared to the normal adults, but there was no difference in serum YKL-40 between the patients with inflammatory joint diseases and OA. The SF levels of YKL-40 were 15-fold higher than serum levels and there was a significant correlation (r = 0.55, P < 0.001) between YKL-40 concentration in SF and serum. Although the tissue distribution of YKL-40 secretion is presently unknown, these observations suggest that a major portion of serum YKL-40 in fact arises from the joint. (ABSTRACT TRUNCATED AT 250 WORDS)
EMG artifacts removal during electrical stimulation, a CWT based technique

A technique of artifacts removal based on the continuous wavelet transform is presented. It uses common mother wavelets to find the temporal localization of stimulation artifacts on electromyogram (EMG) signal during an electrically evoked contraction of a muscle. This method can be used with standard stimulation pulse waveforms like monophasics or biphasics ones. It uses a histogram representation to find the best threshold to apply on the CWT domain. The algotithm is presented with Haar wavelet and then it is used with common wavelet famillies such as Daubechies or Symlets.
FOR TESTOSTERONE AND DIHYDROTESTOSTERONE ANALYSIS IN MALE RAT PLASMA

A new LC-MS/MS method for testosterone and dihydrotestosterone determination in male rat plasma is proposed. After a simple protein precipitation, the compounds were separated on a C18 column with 1 mM ammonium formate solution and methanol in gradient elution at 40°C and detected by an ion trap mass spectrometer after positive electrospray ionisation. The monitoring ions were m/z 97.2, 109.2, 253.2 for testosterone and m/z 255.2 for dihydrotestosterone. The linearity domain was established between 1.0 and 64 ng/mL for both compounds. The ranges of values for withinand inter-day accuracy and precision were 89 111% and 2 13%, respectively. The proposed method is suitable for research purpose such as studies regarding the influence of aromatase inhibitors on male rat plasma levels of testosterone and dihydrotestosterone.
Influences of family obligations and relationships on retirement: variations by gender, race, and marital status.

OBJECTIVE This study examined whether economic and care obligations for family and kin salience influence retirement decisions and whether such influences differ by race, gender, and marital status. DATA Data from the first 2 waves of the National Survey of Families and Households were used. The sample consisted of individuals who were employed at baseline and aged 55-75 at follow-up (N = 897). Cox proportional hazard regressions were used. RESULTS Economic kin obligations impeded the likelihood of retiring. Individuals who made financial contributions to children outside the household and White women with resident children in the household were less prone to retire. Among Blacks, household composition effects were more complex and seemed to depend on the mix of care obligations, financial obligations, and financial contributions by resident kin. Kin salience also impinged on retirement decisions. Some groups who lacked family ties (e.g., nonmarried childless men) were less inclined to retire, whereas other subgroups (e.g., nonmarried men with monthly pre-retirement contacts with children) were more likely to retire. CONCLUSIONS Our data suggest the importance of family obligations and relationships in retirement decisions and demonstrate considerable diversity in these processes. Models of retirement should pay greater attention to the interdependence of work and family spheres and to the diversity of retirement processes among various population groups.
Supporting multimedia recommender systems with peer-level annotations

Peer-level annotation stands for the enrichment of content by any user, who acts as author, being able to make annotations, using, for instance, handwriting or speech recognition capabilities. This type of annotation makes users comfortable when taking digital notes, as they do in every day life. This is an advantage over hierarchical authoring, which is a time-consuming task usually employed by content providers. This paper proposes a content-based recommender architecture which explores information that is available at the time users enhance content. This feature enables our architecture to reach a certain level of semantic information from the content and from user's preferences, which is essential for recommender systems applications.
The organization and projections of the paleostriatal complex in the pigeon (columba livia)

The paleostriatal complex (PC) of the pigeon lies in the basolateral wall of telencephalon, and consists of three major subdivisions: the paleostriatum augmentatum (PA), paleostriatum primitivum (PP), and nucleus intrapeduncularis (INP). The lobus parolfactorius (LPO) lies on the medial aspect of PA and has often been considered to be part of PA. The present study of afferent and efferent connections of the paleostriatal complex supports earlier previous suggestions that the PC is directly comparable to the basal ganglia of mammalia. High concentrations of acetylcholinesterase were found in the PA, LPO and INP. Intense yellowish green fluorescence, probably dopamine, was confined to the PA and LPO.
Intensity- and Gradient-Based Stereo Matching Using Hierarchical Gaussian Basis Functions

We propose a stereo correspondence method by minimizing intensity and gradient errors simultaneously. In contrast to conventional use of image gradients, the gradients are applied in the deformed image space. Although a uniform smoothness constraint is imposed, it is applied only to nonfeature regions. To avoid local minima in the function minimization, we propose to parameterize the disparity function by hierarchical Gaussians. Both the uniqueness and the ordering constraints can be easily imposed in our minimization framework. Besides, we propose a method to estimate the disparity map and the camera response difference parameters simultaneously. Experiments with various real stereo images show robust performances of our algorithm.
Substrate upregulation of the human small intestinal peptide transporter, hPepT1

1 Molecular mechanisms underlying physiological adaptation to increased levels of dietary peptides have been elucidated by studying the response to the substrate glycyl‐L‐glutamine (Gly‐Gln) of the proton‐coupled peptide transporter, hPepT1, in the Caco‐2 human intestinal cell line. Vmax for apical uptake of [14C]glycyl‐[14C]sarcosine was increased 1.64 (± 0.34)‐fold after incubation of Caco‐2 cells for 3 days in a peptide‐rich medium (4 mM Gly‐Gln replacing 4 mM Gln). 2 A full‐length Caco‐2 hPepT1 cDNA clone was identical to human small intestinal hPepT1 with the exception of a single amino acid substitution Ile‐662 to Val. Transcript sizes, on Northern blots of Caco‐2 poly(A)+ RNA probed with a 630 bp 5′ hPepT1 cDNA probe, correspond to the reported band pattern seen with human small intestinal RNA. The dipeptide‐induced increase in substrate transport was accompanied by a parallel increase of 1.92 (± 0.30)‐fold (n= 9) in hPepT1 mRNA. This was in part due to an increase in hPepT1 mRNA half‐life from 8.9 ± 1.1 to 12.5 ± 1.6 h (n= 3), but the increase in half‐life does not account fully for the observed increase in mRNA levels, suggesting that there was also a dipeptide‐mediated increase in hPepT1 transcription. 3 Anti‐hPepT1‐specific antipeptide antibodies localized hPepT1 exclusively to the apical membrane of human small intestinal enterocytes and Caco‐2 cells. Gly‐Gln supplementation of media resulted in a 1.72 (± 0.26)‐fold (n= 5) increase in staining intensity of Caco‐2 cells. 4 We conclude that Caco‐2 cells provide an appropriate model for the study of adaptation of intestinal hPepT1, at the molecular level, to increased levels of dietary peptide. The magnitude of functional increase in apical peptide transport activity in response to Gly‐Gln can be fully accounted for by the increased levels of hPepT1 protein and mRNA, the latter mediated by both enhanced hPepT1 mRNA stability and increased transcription. The signalling pathway between increased dietary peptide and hPepT1 upregulation, therefore, involves direct action on the enterocyte, independent of hormonal and/or neural control.
Fourier Optics and Computer Generated Hologram

Since its conception, holography has been put to a variety of uses including data storage, security, and interferometry. However, perhaps the most popular application of holography is using the technique to make three-dimensional images [1]. This paper describes an algorithm for computationally generating holograms along with methods to fabricate the hologram. Holography has since made a jump from optics tables to computers. The phrase, “digital holography", is common place in the optics community; it describes the methods used to reconstruct holographic images from physically recorded holograms as well as the methods used to construct holograms from virtual objects using a computer. In fact we have the ability to create digital holograms from imaginary objects and then recreate the image of those objects using the same digital holograms, the entire process performed on a single computer. Computer generated holograms printed on transparencies have also been used as optical filters.
Insights into the structure and function of 5-HT2 familyserotonin receptors reveal novel strategies for therapeutic target development

5-HT2 family serotonin receptors, principal sites of action of serotonin in the brain, represent major molecular targets for drugs used in treating a variety of diseases including schizophrenia, depression, anxiety, eating disorders, obsessive-compulsive disorder, chronic pain conditions and obesity. The 5-HT2 family of receptors has three members: 5-HT2A, 5-HT2B and 5-HT2C. Therefore, it is likely that subtype-selective compounds will be needed to avoid serious side effects and to enhance therapeutic indices. Unfortunately, recent insights into the structure and function of 5-HT2A receptors have revealed that structurally-diverse agonists and antagonists have distinct modes of interacting with 5-HT2A receptors, complicating efforts at structure-based drug-design. These distinct binding modes would not have been predicted based on conventional structure-activity relationships or static docking models. Fortunately, these complicated binding modes can be predicted and simulated using molecular dynamics, allowing for the possibility of structure-based drug design. Thus, provided appropriately sophisticated drug design strategies are employed, it is likely that uniquely valuable medications will result which could have great potential for treating a variety of mental and physical illnesses.
Chemical alterations in cell envelopes of polymyxin-resistant Pseudomonas aeruginosa isolates

Cell envelopes from Pseudomonas aeruginosa strains resistant to polymyxin were compared with cell envelopes from polymyxin-sensitive strains as to their content of total protein, carbohydrate, and 2-keto-3-deoxyoctonate and as to their protein composition as determined by slab polyacrylamide gel electrophoresis. The cell envelopes of the polymyxin-resistant strains had reduced amounts of lipopolysaccharide, as indicated a reduction in both carbohydrate and 2-keto-3-deoxyoctonate concentrations, and a greatly altered protein composition as shown by polyacrylamide gel electrophoresis. There was a quantitative increase in total cell envelop protein in these strains. However, those protein bands identified as being major outer membrane proteins upon polyacrylamide gel electrophoresis of separated outer and cytoplasmic membranes were reduced greatly in concentration in the polymyxin-resistant cell envelopes. Thus, it appears that polymyxin resistance in these strains is associated with the alteration of the outer membrane through a loss of lipopolysaccharide and outer membrane proteins.
Full length vascular cell adhesion molecule 1 (VCAM-1).

We have developed several monoclonal antibodies that bind specifically to IL-1 activated but not to quiescent human unbilical vein endothelial cells (HUVEC). Two antibodies, 1E7 and 2G7, were shown to react at distinct epitopes with a novel IL-1 inducible sialoglycoprotein which is implicated in the adhesion of T cells with activated endothelium (1). We used polymerase chain reaction (PCR, 2, 3) to clone VCAM-1 cDNA in order to test the relationship of VCAM-1 to 1E7/2G7 protein. The coding region of VCAM-1 cDNA was cloned from poly A RNA isolated from IL-1 activated HUVEC by PCR using the two following primers encompassing the start and stop codons respectively. Primer 1: 5'-GGGGGGCGGCCGCGCAACTTAAAATGCCTGGGAAGATG-3' Primer 2: 5'-GGGGGCTCGAGCATTAGCTACACTTTTGATTTCTGTG-3' The primers were designed to contain NotI and Xhol sites at the 5' and 3'ends of the cDNA, respectively. The PCR product was approximately 2.3 Kb instead of the expected 1.96 Kb band based on the published sequence (4). The 2.3 Kb band was purified and cloned into an expression vector. Four clones were sequenced completely using the primers given in Table 1. All of them contained an insert of 276 nucleotides after the nucleotide position 1034 of the published sequence (4). In addition four more clones were sequenced at the insert region. Seven out of eight clones sequenced contained identical insert sequence and one clone contained the following changes: C for T, C for A, and a deletion of C at nucleotide positions 1193, 1196, and 1198 respectively of the sequence given in Figure 1. The sequence for the 276 nucleotide insert (overlined in Figure 1) was further confirmed by direct sequencing of the PCR amplified product and found to contain the same sequence as shown in Figure 1. The four clones sequenced in entirety contained other random errors at positions corresponding to the sequence given in Figure 1. Cl # 1 — G for A at positions 102 and 270 respectively; Cl #2 Table 1.
Concurrency and recovery in full-text indexing

An important feature of a document database system is that the documents can be retrieved by searching for words from their contents. In a full-text index, each word of the stored documents can be used as a search key. Inserting a new document into the database automatically triggers a transaction that inserts the words together with their occurrence information into the index. We present solutions to problems that arise when full-text indexing is applied for constantly changing document data, such as WWW pages. We present and analyze an algorithm for full-text indexing with the following properties: concurrent searches are possible and efficient, and the algorithm can be designed such that several indexing processes can be performed concurrently. Moreover, the algorithm allows efficient recovery of the index after failures that can occur while the index is modified. This is important for large indices, because when not prepared for failures, the index may need to be reconstructed from original documents.
Das zusätzliche Bildungsangebot in Sachsen-Anhalt: Eine Bestandsaufnahme

Das vorliegende Papier gibt einen Uberblick uber das zusatzliche Bildungsangebot im Land Sachsen-Anhalt. Als zusatzlich werden dabei solche Ma_nahmen und Programme verstanden, die neben dem Regelschul-, Ausbildungs- und Studiensystem auf Initiative unterschiedlicher Akteure eingerichtet werden. Ziel des Uberblicks ist es, die Vielfalt dieses Angebots im Hinblick auf die Zielsetzungen, aber auch auf die Verteilung entlang des Bildungswegs von der Elementarbildung bis zum Hochschulstudium und der Weiterbildung im Erwerbsleben zusammenfassend und ubersichtlich darzustellen. Am Ende werden die Auswahl und Ausgestaltung der Programme auf der Grundlage ausgewahlter Ergebnisse der bildungsokonomischen Forschung diskutiert und weitergehender Forschungsbedarf identifiziert.