Miracle-dz/UniFAR-FTUs huggingface dataset:
Is Comparison the Thief of Joy? Sexual Narcissism and Social Comparisons in the Domain of Sexuality

Are people who are high in sexual narcissism more sensitive to information comparing their sex lives with the sex lives of others? Does this sensitivity explain narcissists’ lower sexual and relationship satisfaction? We conducted three studies to address this question. Participants completed the Sexual Narcissism Scale (Widman & McNulty, 2010), and then either recalled (Study 1), imagined (Study 2), or actually made (Study 3) a sexual comparison. We found that people high in sexual narcissism (compared with those lower in sexual narcissism) were more bothered when comparing themselves with someone with a higher sexual frequency and felt better about a comparison with someone with a lower sexual frequency. In turn, narcissists’ greater sensitivity to upward social comparisons predicted lower sexual and relationship satisfaction. These results suggest that those high in sexual narcissism may use downward sexual comparisons to maintain their grandiose self-views and be particularly sensitive to upward sexual comparisons.
Insight into understanding the anatomical and clinical aspects of supernumerary rectus capitis posterior muscles

Rectus capitis posterior muscles are located in the suboccipital triangle and function in extension and lateral rotation of the head and neck. There are two of these muscles on each side: the rectus capitis posterior major and the rectus capitis posterior minor. This study describes the presence of a third suboccipital muscle in a 55‐year‐old cadaver. In addition to highlighting the possible relationship between these muscles and cervicogenic headaches or balance in an individual, we also relate this observation to similar musculature in the cat that have been shown to effect crucial functions. Clin. Anat. 18:373–375, 2005. © 2005 Wiley‐Liss, Inc.
Resolution of infectious parameters after antimicrobial therapy in patients with ventilator-associated pneumonia.

Although recommended durations of antimicrobial therapy for ventilator-associated pneumonia (VAP) range from 7 to 21 d, these are not based on prospective studies and little is known about the resolution of symptoms after start of antibiotics. Resolution of these symptoms was investigated in 27 patients. VAP was diagnosed on clinical, radiographic, and microbiological criteria, including quantitative cultures of bronchoalveolar lavage. All patients received appropriate antibiotic therapy. Highest temperatures, leukocyte counts, Pa(O(2))/FI(O(2)) ratios, and semiquantitative cultures of endotracheal aspirates were recorded from start of therapy until Day 14. Resolution was defined as the first day that these parameters fulfilled the following definition: temperature < or = 38 degrees C, leukocytes < or = 10 x 10(9)/L, Pa(O(2))/FI(O(2)) ratio > or = 25 kPa, and no or +1 of bacterial growth of etiologic pathogens in cultures of endotracheal aspirate. VAP was caused by Enterobacteriaceae (n = 14), P. aeruginosa (n = 7), S. aureus (n = 6), H. influenzae (n = 3), and S. pneumoniae (n = 1). H. influenzae and S. pneumoniae were eradicated from tracheal aspirates, whereas Enterobacteriaceae, S. aureus, and P. aeruginosa persisted, despite in vitro susceptibility to antibiotics administered. Significant improvements were observed for all clinical parameters, most apparently within the first 6 d after start of antibiotics. Newly acquired colonization, especially with P. aeruginosa and Enterobacteriaceae, occurred in the second week of therapy. Six patients developed a recurrent episode of VAP, four of them with P. aeruginosa. Clinical responses to therapy for VAP occur within the first 6 d of therapy, endotracheal colonization with Gram-negative bacteria persists despite susceptibility to therapy, and acquired colonization usually occurs in the second week of therapy and frequently precedes a recurrent episode.
Higher levels of antibodies against the psoriasis-associated antigen pso p27 in cerebrospinal fluid from patients with low back pain and sciatica.

STUDY DESIGN A prospective study comparing the presence of antibodies against the psoriasis-associated antigen pso p27 in pain-free control subjects and patients with low back pain and/or sciatica. OBJECTIVES To analyze the amount of local inflammation present in human lumbar disc disorders, using anti-pso p27 antibodies in the cerebrospinal fluid as a marker and to analyze whether pain intensity correlates with this marker of inflammation. SUMMARY OF BACKGROUND DATA Pso p27 is a major antigen in psoriasis that is also present, mostly locally, in other inflammatory disorders, such as sarcoidosis, inflammatory bowel disease, and ankylosing spondylitis, inflammation is also thought to play a major role in the generation of lumbar and radicular pain in degenerative disc disorders. METHODS Anti-pso p27 antibodies in cerebrospinal fluid were quantified using an indirect enzyme-linked immunosorbent assay with pso p27 obtained from patients with psoriasis for use as an antigen. Fifteen patients with spinal stenosis, 11 patients without myelographic disc herniation, 17 patients with disc herniation, and 24 pain-free patient control subjects were studied. RESULTS Significantly higher levels of anti-pso p27 antibodies were found in patients with myelographic signs of disc herniation than in with patients with no signs of herniation, patients with spinal stenosis, and control subjects. Patients with no known signs of disc herniation and patients with myelographic signs of spinal stenosis (< 10 mm in diameter) caused by degenerative changes, had higher levels of anti-pso p27 antibodies than did control subjects. However, these differences reached only borderline statistical significance. CONCLUSIONS The results support those in previous reports, that inflammation probably plays an important role in degenerative disk disorders, particularly in disk herniations. That there was no correlation between pain intensity and anti-pso p27 activity indicates that the antigen is probably not essential in pain generation per se. The results may indicate that pso p27 is expressed secondary to, not as an initiator of, inflammation.
piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire

In this study, Senti et al investigate how cytoplasmic post-transcriptional silencing influences transcriptional silencing in the nucleus. They show that Piwi-bound piRNA populations depend almost exclusively on prior piRNA-guided transcript slicing, thus providing further insight into the regulation of piRNA biogenesis in the developing Drosophila ovary.
Reactivity of monoclonal antibodies EG1 and EG2 with eosinophils and their granule proteins

Use of the murine monoclonal antibodies EG1 and EG2 has been based on the assumption that EG2 recognizes activated eosinophils. We examined the reactivity of EG1 and EG2 with eosinophil cationic protein (ECP), eosinophil‐derived neurotoxin (EDN), and stimulated and nonstimulated eosinophils from normal donors. By radioimmunoassay, EG1 recognized only ECP, whereas EG2 recognized both ECP and EDN. By Western blot, EG1 reacted with ECP, EG2 reacted with both ECP and EDN, but EG2 could not distinguish between lysates of stimulated and nonstimulated eosinophils. By immunofluorescence, EG1 and EG2 at 20 μg/mL stained 95–100% of nonstimulated eosinophils, regardless of fixative; EG1 and EG2 at 0.1 μg/mL stained 61–90% of acetone‐ and paraformaldehyde‐fixed and only 5–21% of methanol‐fixed nonstimulated eosinophils. Thus, the reactivity of EG1 and EG2 with eosinophils depends on the method of fixation and antibody concentration; and EG2, in contrast to previous reports, cannot reliably discriminate between resting and activated eosinophils. J. Leukoc. Biol. 66: 447–454; 1999.
Hedging Demands under Incomplete Information

I present a model of consumption and portfolio choice under market incompleteness and imperfect information regarding the investment opportunity set. I solve analytically the consumption and portfolio choice problem for an investor learning about the true state of the economy. When prices are the only observations, the previously unspanned state variables are spanned by the market securities under the optimal inference/learning process. The market is observationally complete for the imperfectly informed investor. I show how learning affects both the covariance and the duration component of the hedging portfolio. I apply the model to the case where the Sharpe ratio is mean reverting. For the parameters presented in Wachter (2002), I show a reduction in hedging demands due to imperfect information. I solve in closed-form for the model implied R for the return forecast regression. I discuss the relationship between the reduction in hedging demands and the reduction in the model implied R for the return forecast regression. ∗Ph.D. Candidate, Sloan School of Management, Massachusetts Institute of Technology. Corresponding Address: MIT Sloan School of Management; 50 Memorial Drive, E52-458; Cambridge, MA 02142. E-mail: jfr@mit.edu. I thank my advisors Jonathan Lewellen and Steve Ross for their guidance. This paper benefitted from suggestions by John Campbell, George Chacko, Robin Greenwood, Jonathan Lewellen, Leonid Kogan, Stavros Panageas, Anna Pavlova, Steve Ross, Dimitri Vayanos, Luis Viceira, and Joshua White. I gratefully acknowledge the financial support of the General Electric Faculty for the Future Fellowship. All errors are mine. Updated versions of the paper are available in my website: www.mit.edu/~jfr/researchS02.
Identification of Brucella abortus OxyR and Its Role in Control of Catalase Expression

ABSTRACT We report the cloning and sequencing of the Brucella abortus oxyR homolog and provide evidence that the transcription product of this gene binds to the B. abortus catalase promoter region. A gene replacement/deletion Brucella oxyR mutant exhibits increased sensitivity to prolonged exposure to H2O2 and is unable to adapt to H2O2 in the environment.
Type 1 fuzzy sets in complex control applied to evaluation of resort management system

The evaluation of Resort Management System (RMS) quality is an item of many trials. We propose applying a complex system of two control algorithms to provide a final estimation of RMS. This distinct quality value will be dependent on some individual appreciations assigned by customers to basic services. We also discuss some improvements concerning the fuzzification parts of controllers.
Proteomic Analysis of Barley Cell Nuclei Purified by Flow Sorting

Many proteins are present in the nucleus; some are involved with its structural and functional organization, some with gene expression, and some with cell division. The plant nuclear proteome has not been well explored. Its characterization requires extraction methods which minimize both the artifactual alteration of the proteins and the extent of contamination with non-nuclear proteins. The conventional multi-step fractionation procedure is both laborious and prone to contamination. Here, we describe a single-step method based on flow sorting. The method allows the separation of G1, S and G2 phase nuclei and minimizes the risk of contamination by non-nuclear proteins. Preliminary results obtained using G1 phase cell nuclei from barley root tips indicate that flow sorting coupled with a protein/peptide separation and mass spectrometry will permit a comprehensive characterization of the plant nuclear proteome.
Seasonality of Mania in New Zealand

This paper examines the seasonal variation in manic admissions over a five year period in New Zealand. There is a significant monthly variation in admission rates with a spring/summer peak. Breakdown by sex, age and admission status suggested that there is no particular subgroup responsible, but that young first admissions and older female readmissions do not follow this trend. Examination of the monthly admission rates revealed that this peak is not constant from year to year. Possible mechanisms, which link fluctuating environmental variables with an irregular spring/summer peak for manic admissions, are discussed.
Evaluation of a dermatoglyphic index to detect placental type variation in MZ twins

A dermatoglyphic index, which was previously used retrospectively to assess relationships between placental type in MZ twins with other variables, was tested for verification in two new separate samples of twins of known placental type. In both a French twin sample (19 monochorionic and 24 dichorionic) and the U.S. twin sample (49 monochorionic and 22 dichorionic), dermatoglyphic index scores were higher in monochorionic than dichorionic pairs. The difference in scores attained statistical significance when the two new samples were pooled. It is concluded that although the index cannot be used retrospectively to classify an individual MZ twin pair, an association of the placental type dermatoglyphic score with another variable in a group of MZ twins without any placentation information provides support for continuing to investigate prenatal effects on the associated variable. Am. J. Hum. Biol. 9:609–615, 1997. © 1997 Wiley‐Liss, Inc.
ANTIBODY RESPONSE IN MARASMIC CHILDREN DURING RECOVERY

Abstract. The I, II and III antibody responses to tetanus and diphtheria were assessed in marasmic and moderate protein‐calorie malnourished children and compared to that of controls. The results suggest that during recovery marasmic children are capable of responding adequately to tetanus and diphtheria vaccines.
Combining Slicing and Constraint Solving for Better Debugging: The CONBAS Approach

Although slices provide a good basis for analyzing programs during debugging, they lack in their capabilities providing precise information regarding the most likely root causes of faults. Hence, a lot of work is left to the programmer during fault localization. In this paper, we present an approach that combines an advanced dynamic slicing method with constraint solving in order to reduce the number of delivered fault candidates. The approach is called Constraints Based Slicing (Conbas). The idea behind Conbas is to convert an execution trace of a failing test case into its constraint representation and to check if it is possible to find values for all variables in the execution trace so that there is no contradiction with the test case. For doing so, we make use of the correctness and incorrectness assumptions behind a diagnosis, the given failing test case. Beside the theoretical foundations and the algorithm, we present empirical results and discuss future research. The obtained empirical results indicate an improvement of about 28% for the single fault and 50% for the double-fault case compared to dynamic slicing approaches.
Spectral components of heart rate variability determined by wavelet analysis

Spectral components of heart rate variability (HRV) are determined in the time-frequency domain using a wavelet transform. Based on the finer estimation of low-frequency content enabled by the logarithmic resolution of the wavelet transform, corrections of spectral intervals, already defined by Fourier and model based methods, are proposed. The characteristic peaks between 0.0095 and 0.6 Hz are traced in time and four spectral intervals are defined, I (0.0095-0.021 Hz), II (0.021-0.052 Hz), III (0.052-0.145 Hz) and IV (0.145-0.6 Hz), within which peaks are located for all subjects included. These intervals are shown to be invariant regardless of the age and the state of the system. We also show that the frequency and power of the spectral components are related to age, AMI and particularly to type II diabetes mellitus.
Retina and optic nerve after posterior ciliary artery occlusion. An experimental study in squirrel monkeys.

After experimental occlusion of the posterior ciliary arteries in one eye of squirrel monkeys, retinal pigment epithelial atrophy occurred in geographic patches, but much of the retinal area, especially in the peripapillary region, remained normal. Only minute areas of atrophy occurred in the optic nerve head, presumably because of protection afforded by anastomotic connection to the vessels of the pia mater and retina. Assuming that circulatory dynamics of monkeys and humans are similar, ischemic papillitis must represent disease of more than just the posterior ciliary arteries. In glaucomatous cupping, intraocular pressure may affect circulation by capillary or venous compression, but there has been undue emphasis on the fact that the short posterior ciliary arteries supply the disc, as well as unwarranted assumptions that the responses of the optic disc blood flow can be predicted from studies of choroidal circulation.
Effect of Lip Closure on Facial Growth in the Surgically Induced Cleft Rabbit

This project was designed to determine whether cleft lip repair has an influence on facial growth. To study this, 62 rabbits were divided into four groups: control, control without repair, Millard-type repair, and Bardach-type repair. Surgical clefts of the lip, alveolus, and the palate were created in 6-week-old rabbits. Periodic measurements were made of the pressure exerted by the lip on the maxillary alveolus. The animals were killed 20 weeks postoperatively. The skulls were processed and measurements were taken from the skulls. The pressure measurements showed a definite increase in lip pressure on the maxillary alveolus for the lip repair group. This pressure was high soon after surgery, rapidly returned toward the control level, but never reached it. Skull measurements indicate an inhibition in anterior maxillary growth for the “control without repair” group. This inhibition was even more profound in the two lip repair groups. No significant differences were found in maxillary width or mandibular length. When correlations were made to see if increased lip pressure resulted in decreased anterior maxillary growth, a significant correlation was found for both lip repair groups. This means that as the pressure of the lip repair increased, it resulted in a decrease in anterior maxillary growth. The data reported here indicates that cleft lip surgery must be considered as having a definite influence on anterior maxillary growth inhibition observed in the cleft lip and palate population. Further studies are indicated to determine the role of cleft palate repair on facial growth.
Modelos de elementos finitos de propagação de ondas, dreams e epe_cg - aplicação à marina do lugar de baixo

Descrevem-se dois modelos que resolvem a equacao de declive suave, denominados DREAMS e EPE_CG. O modelo DREAMS utiliza a formulacao classica do metodo dos elementos finitos para resolver a equacao de declive suave, o que leva a montagem da matriz global do sistema. O modelo EPE_CG utiliza uma formulacao denominada elemento por elemento (EPE), para resolver aquela equacao. Neste tipo de formulacao EPE, nao ha a montagem da matriz global do sistema, o que traz grande economia nos requisitos de armazenamento. Ambos os modelos efetuam a refracao e difracao de ondas maritimas em zonas portuarias e sao adequados quer para estudos de agitacao, quer de ressonância em portos e zonas abrigadas. Os dois modelos numericos sao aplicados ao estudo de agitacao no interior da marina do Lugar de Baixo, situada na costa sul da ilha da Madeira, em Portugal, para varias condicoes de onda incidente. De modo a avaliar as vantagens e desvantagens de cada um dos modelos na sua aplicacao a zonas portuarias, os resultados de ambos os modelos numericos sao comparados em termos do tempo de CPU e memoria necessaria para as varias condicoes de teste. Palavras-chave: Zonas portuarias e costeiras; propagacao e deformacao de ondas; refracao-difracao e reflexao de onda; metodo dos elementos finitos; formulacao elemento por elemento.
Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation.

The crystal structure of a constitutively active multiple site mutant of plasminogen activator inhibitor 1 (PAI-1) was determined and refined at a resolution of 2.7 A. The present structure comprises a dimer of two crystallographically independent PAI-1 molecules that pack by association of the residues P6 to P3 of the reactive centre loop of one molecule (A) with the edge of the main beta-sheet A of the other molecule (B). Thus, the reactive centre loop is ordered for molecule A by crystal packing forces, while for molecule B it is unconstrained by crystal packing contacts and is disordered. The overall structure of active PAI-1 is similar to the structures of other active inhibitory serpins exhibiting as the major secondary structural feature a five-stranded beta-sheet A and an intact proteinase-binding loop protruding from the one end of the elongated molecule. No preinsertion of the reactive centre loop is observed in this structure.A comparison of the present structure with the previously determined crystal structures of PAI-1 in its alternative conformations reveals that, upon cleavage of an intact form of PAI-1 or formation of latent PAI-1, the well-characterised rearrangements of the serpin secondary structural elements are accompanied by dramatic and partly unexpected conformational changes of helical and loop structures proximal to beta-sheet A. The present structure explains the stabilising effects of the mutated residues, reveals the structural cause for the observed spectroscopic differences between active and latent PAI-1, and provides new insights into possible mechanisms of stabilisation by its natural binding partner, vitronectin.