Miracle-dz/UniFAR-FTUs huggingface dataset:
Biological Investigation of the Ethanolic Extract of Polygonum Hydropiper (L), Coccinia Grandis (L) and Litsea Glutinosa (Lour.)

Polygonum hydropiper, Coccinia grandis and Litsea glutinosa are common plants in Bangladesh. It has been reported to Coccinia grandis have medicinal activities like hypoglycemic, antibacterial, antifungal and Litsea glutinosa used for used as demulcent for ulcer; also for dysentery. The leaf of Polygonum hydropiper plant has shown cytotoxic and thrombolytic activity. In this study, extracted mixture from Polygonum hydropiper, Litsea glutinosa and Coccinia grandis, were studied for antibacterial, thrombolytic, cytotoxic and scavenging activity by using in vitro techniques. Analgesic activity was tested using in vivo techniques. Ethanol extract of the plants were tested for Antibacterial activity using disc diffusion method. Ethanolic extract of the plants were tested for brine shrimp lethality bioassay using brine shrimp nauplii. The LC50 of ethanol extract of Polygonum hydropiper extract was found to be 6. 02μg/ml indicates that extracts have good pharmacological action. The ethanol extract of the extracts were also tested for in vitro thrombolytic activity. The extract showed reasonable thrombolytic activity. Litsea glutinosa showed very good analgesic activity having percent inhibition of writhing about 76.65. Coccinea grandis has extremely good scavenging activity having the IC50 of 1. 67μg/ml. Further investigation on the plant is required to confirm their pharmacological activity and thereby utilizing them as useful medicinal plant.
Mercado Social de Emprego na Região Autónoma dos Açores: análise da implementação de uma política pública

O presente trabalho tem por objetivo apresentar, de forma concisa e sistematizada, atraves de pesquisa e analise bibliografica, uma analise a implementacao da politica publica, o Mercado Social de Emprego na Regiao Autonoma dos Acores. Contextualizando esta politica no quadro mais vasto das politicas sociais implementadas em Portugal, considerando que as politicas publicas sao respostas do poder publico as problematicas sociais, apresentando-se como estrategias que institucionalizam um conjunto de acoes sistematicas para alcancar determinados fins considerados de interesse publico. A formulacao e implementacao das politicas publicas dependem e sao resultado da interacao de inumeras logicas de atores, sejam eles individuais ou coletivos, sejam eles publicos ou privados. Neste sentido, o presente trabalho desenvolve uma concecao teorica sobre a analise de politicas, enquanto uma metodologia de estudo, compreendendo as categorias: atores, conteudo, contexto e processo, onde nesta ultima, sao especificados os processos de construcao de uma agenda, a formulacao e a implementacao de uma politica. Por fim, serao dados contributos para uma possivel revisao desta politica publica.
Predicting interest rates in real-time

We analyse the predictive ability of real-time macroeconomic information for the yield curve of interest rates. We specify a mixed-frequency macro-yields model in real-time that incorporates interest rate surveys and that treats macroeconomic factors as unobservable components. Results indicate that real-time macroeconomic information is helpful to predict interest rates, and that data revisions drive a superior predictive ability of revised macro data over real-time macro data. Moreover, we find that incorporating interest rate surveys in the model can significantly improve its predictive ability.
Identification and epistasis analysis of quantitative trait loci for zeaxanthin concentration in maize kernel across different generations and environments

Zeaxanthin, a natural fat-soluble pigment, not only increases plant resistance, but also has vital significance for human health. However, quantitative trait loci (QTL) and the epistatic effects of zeaxanthin concentration in maize kernel have not been well studied. To identify QTLs and analyse the epistatic effects of zeaxanthin concentration in maize kernel, two sets of segregating generations derived from the cross between HuangC (a high zeaxanthin concentration inbred line) and Rezi1 (a low zeaxanthin concentration inbred line) were evaluated in three different environments. One major-effect QTL, qZea6a, explains 41.4–71.4% of the phenotypic variation and two QTLs, qZea4a and qZea3a, show LOD > 3 for zeaxanthin concentration detected over two generations and three different environments. Four of the ten QTL pairs show epistatic effects, explaining 7.34–14.3% of the phenotypic variance. Furthermore, additivity was the major allelic action at zeaxanthin concentration QTLs located in F2 and F2:3 populations and plants with homozygous HuangC alleles have a strong genetic ability in enhancing zeaxanthin concentration in maize kernel. These results will contribute to understanding these complex loci better and provide awareness about zeaxanthin concentration to maize breeders and scientists involved in maize research.
Secondary antibody deficiency and immunoglobulin replacement

Abstract Antibody deficiencies can be either primary or secondary, leading to significant morbidity and mortality without appropriate management. Secondary antibody deficiency can be due to various diseases or iatrogenic causes, especially with the use of immunosuppressive agents such as B-cell depleting therapies. Unlike its primary counterpart, little is known regarding the management of secondary antibody deficiency and it remains an underappreciated entity. This is a growing concern with the growing numbers of patients on various immunosuppressant therapies and increasing survivors of autoimmune diseases and haematological malignancies. In this report, we review the diagnosis and management of secondary antibody deficiency, especially after rituximab-induced hypogammaglobulinemia.
Longitudinal Assessment of Maxillary and Mandibular Molar and Incisor Dentoalveolar Heights and Growth Rates in Class I Subjects with Varied Craniofacial Growth Patterns as Classified by Directional and Proportionate Methods

Objective: To determine if significant differences exist in dentoalveolar heights and dentoalveolar height growth rates, among skeletal Class I subjects that exhibit differing craniofacial growth patterns. Methods: One hundred and five subjects with cephalograms available at 9, 12, 14, and 16 years were categorized into directional (change in Y-axis angle) and proportionate (UFH:LFH) growth pattern groups. Maxillary and mandibular molar and incisor dentoalveolar heights and dentoalveolar height growth rates were determined. Comparisons were made by mixed model and ANOVA. Results: Neither dentoalveolar heights, nor growth rates differed significantly among directional classification groups in either gender. All dentoalveolar heights differed significantly among all proportionate classification groups at all ages in both male and female subjects. Conclusions: No statistically significant differences were found in dentoalveolar heights or dentoalveolar height growth rates of different directional growth pattern groups. Statistically significant differences were found in all dentoalveolar heights of different proportionate growth pattern groups.
Teaching social skills to people with autism

phia, PA: Lippincott Williams and Wilkins. Sen, A. (1999). Development as freedom. New York, NY: Oxford University Press. Sen, A. (2009). The idea of justice. Cambridge, MA: Belknap Press of Harvard University Press. Stein, F. , & Cutler, S. K. (2001). Psychosocial occupational therapy: A holistic approach. New York, NY: Delmar Thomson Learning. Vizard, P., Fukuda-Parr, S. , & Elson, D. (2011). Introduction: The capability approach and human rights. Journal of Human Development and Capabilities, 12, 1–22. doi:10.1080/19452829.2010. 541728 Watson, R. M. (2006). Being before doing: The cultural identity (essence) of occupational therapy. Australian Occupational Therapy Journal, 53, 151–158. doi:10.1111/j.1440-1630.2006. 00598.x World Federation of Occupational Therapists. (2006). Position statement: Human rights. Retrieved from http://www.wfot. org/ResourceCentre.aspx World Federation of Occupational Therapists. (2011). Statement on occupational therapy. Retrieved from http://www.wfot. org/Portals/0/PDF/STATEMENT%20ON%20OCCUPATIONAL%20TH ERAPY%20300811.pdf World Health Organization. (2008). Closing the gap in a generation: Health equity through action on the social determinants of health. Final report of the Commission on Social Determinants of Health. Retrieved from http://whqlibdoc.who. int/publications/2008/97892 41563703_eng. pdf World Health Organization. (2010). Mental health and development: Targeting people with mental health conditions as a vulnerable group. Retrieved from http://whqlibdoc.who. int/publications/ 2010/9789241563949_eng. pdf Wright-St. Clair, V. (2012). The case for multiple research methodologies. In G. E. Whiteford & C. Hocking (Eds.), Occupational science: Society, inclusion, participation (pp. 137–151). Hoboken, NJ: Wiley-Blackwell. Yerxa, E. J. (1967). 1966 Eleanor Clarke Slagle lecture: Authentic occupational therapy. American Journal of Occupational Therapy, 21, 1–9.
Eliminatie van mazelen en rubella in 2010: halen we de doestelling?

Mazelen is een van de meest besmettelijke infectieziekten waarbij tot in 30% van de gevallen complicaties optreden. Het congenitaal rubellasyndroom is een verzamelnaam voor de afwijkingen die kunnen optreden bij een kind waarvan de moeder tijdens de zwangerschap besmet werd met rubella. Het Regionaal Bureau voor Europa van de Wereldgezondheidsorganisatie gaf in 2010 prioriteit aan de eliminatie van mazelen en het congenitaal rubellasyndroom. Dit artikel beschrijft de belangrijkste klinische en diagnostische aspecten van mazelen en van het congenitaal rubellasyndroom. Vervolgens wordt een overzicht gegeven van de surveillance van mazelen en rubella in Belgie. Hieruit blijkt dat ook in 2009 er nog verschillende gevallen van mazelen voorkwamen. De eliminatiedoelstelling kan bereikt worden maar vraagt een blijvende inspanning van alle gezondheidswerkers.
Examining the Most Important Determinants of Health-Related Quality of Life (HRQoL). The Machine Learning Approach

There are various circumstances affecting the individual health-related quality of life (HRQoL). The aim of the paper is to understand which health determinants are the most crucial while designing the efficient health policy. Using the machine learning approach, authors examine 42 health status related factors. The paper incorporates 27 individual level and 15 regional level health state determinants in empirical investigation. Results show that in terms of factor weights, the subjective health is the most influential on individual level and medical labor force - on regional level. However, in terms of frequency, the hospital visiting plays the most important role on individual level and estate condition - on regional level. In addition, empirical results indicate that individual level factors have higher impact on health status than regional level factors. Based on empirical results of the paper, authors provide policy recommendations.
Preliminary results of postoperative pain and complications after hemorrhoidectomy with harmonic scalpel Resultados preliminares de dor pós-operatória e complicações após hemorroidectomia com bisturi harmônico

Objective: To assess pain and to describe the complications after hemorrhoidectomy (Milligan-Morgan technique) using the harmonic scalpel. Methods: The sample was composed of 108 patients. The hemorrhoidal tissue was dissected and the vascular pedicle was sectioned using the harmonic scalpel (no ligation technique). Pain and postoperative complications rates were calculated. Results: Significant postoperative pain occurred in 3.7% of cases (use of opioid drugs). The postoperative complication rate was 9.2%: bleeding was observed in three cases (2.8%), infection in one case (0.9%), anal stenosis in one case (0.9 %) and transitory urgency evacuation in five cases (4.6%). Conclusions: The Milligan-Morgan hemorrhoidectomy with harmonic scalpel is an attractive surgical technique owing to the low frequency of pain and postoperative complications.
Potensi Desa Leran Kulon sebagai Desa Wisata di Kecamatan Palang, Kabupaten Tuban

This paper is about the architecture and tourism that is the tourism potential of Leran Kulon, Tuban District, East Java. This village potencies consists of the natural resources, the human resources, an infrastructure resources and a supporting institution. The method used qualitative research method that data collected through interview, observation, and literature review. The result showed that Leran Kulon Village potencies are the fabulous natural landscape and the local wisdom that will develop as a tourist attraction.
Analysis of treatment satisfaction among patients with type 2 diabetes

Introduction: Treatment of diabetes is complex and includes lifestyle intervention and pharmacologicalmanagement. Treatment satisfaction is a significant factor in improving health care. Special importance is given to diabetes because of its need for lifelong therapy. Aim: To determine the influence of certain socio-demographic and clinical factors on treatment satisfaction of patients with type 2 diabetes. Material and methods: A cross sectional study was conducted among 40 consecutive outpatients. Data was collected through two questionnaires. The first questionnaire consisted of socio-demographic and clinical data. The second one was a standardized Diabetes Treatment Satisfaction Questionnaire (DTSQs). Results: Of the studied patients, the majority were women (52,5%), patients in their sixties (55%), patients who only finished high school (55%), patients who were using insulinand OAD (50%), as well as patients who have developed chronic diabetic complications (80%). It was observed that treatment satisfaction among patients who have had diabetes for longer than twenty years was significantly lower than among those who have been treated for diabetes for less than ten years (4,30 ± 0,77 vs. 4,99 ± 0,63, p = 0,046). Patients who were taking tablets were significantly more satisfied with treatment (5,35 ± 0,38, p ˂ 0,001). Patients withoutany diabetic complication were significantly more satisfied with the treatment than those who have developed at least one diabetic complication (5,19 ± 0,87 vs. 4,59 ± 0,57, p = 0,023). Multiple regression analysis revealed that elementary education(p = 0,037), insulin (p ˂ 0,001) and any diabetic complication (p = 0,007) were independently associated with lower treatment satisfaction. Conclusion: Using DTSQ we noticed important socio-demographic and clinical factors that influence the satisfaction with the current therapy. Low educational level, insulin, having any diabetic complication and diabetes duration were associated with lower treatment satisfaction. Having identified this vulnerable group, we must place emphasis on the need of providing additional attention and assistance to these patients, in order to improve their health and clinical outcome.
Chemical characterization and in vitro antioxidant capacity of nine Algerian date palm cultivars (Phoenix dactylifera L.) seed oil

Date pits are another major date palm crops and low grade rejected, used locally in the management of diabetes and as animal feed ingredient or turned into non-caffeinated coffee by the Arabs although their richness with valuable bioactive and antioxidant compounds. In this study and for the first time, lipids, fatty acids profiles, total tocopherols and sterols of nine (9) Algerian date palm cultivars (Phoenix dactylifera L.) seed oil were investigated and their antioxidant activities were evaluated. Oil yield ranged from 4.86% to 6.7% . Gas liquid chromatography revealed that the oil fraction contained unsaturated fatty acids in majority with the preponderance of oleic acid (37.83–55.00%) followed by lauric and myristic acids (6.63–25.36% and 9.30–19.33%) respectively. The study of the unsaponifiable fraction revealed the presence of sterols and tocopherols. The sterols contents ranged from 4.7 to 8.45 mg/g DW. Whereas, the levels of total tocopherols ranged from 0.32 to 0.74 mg/DW, which α-tocopherol was the predominant tocopherol (15.57% – 74.1%) followed by (β+γ)-tocopherol (25.12% – 56.01%). The antioxidant activity of date seeds oil was determined with DPPH radical scavenging assays. The oils had a moderate bleaching effect on DPPH free radicals, where Ghars (GH), Sbo3 Lossif (SL) and Timjhourt (TIM) seed oils were the active ones. The richest of date seed oil by active components such sterols, tocopherols also high amounts of oleic, lauric and other fatty acids suggest it to be as a useful source of edible oils for human consumption as well as using as additives in food, for medicinal use, in cosmetics, pharmaceuticals and food industries.
Use of Non-Informative Prior in Estimating Population Proportion

Randomized response techniques are designed for protecting the privacy of respondents and reducing the response bias while eliciting information on sensitive issues. Linear function of sample proportion is commonly used for estimating population proportion. By illustrating with the Warner (1965) model, we investigate the estimation problem of choosing estimators from various perspectives including minimizing the average mean square error and squared average bias of linear estimators. Three practical estimators are proposed, and these are compared with the regular estimator with respect to mean square error criterion. The results also cover to the case of direct response surveys. In particular, one of the proposed estimators may be viewed as a generalization of Böhning and Viwatwongkasem (2005) estimator.
Long Term Macular Changes in an Impending Macular Hole after Vitrectomy in a Patient with Macular Telangiectasia Type 2

Purpose: To report and review a bilateral long term follow up case of pars plana vitrectomy of macular telangiectasia (MacTel) type 2 associated impending macular hole. Case summary: A 61-year-old male presented with decreased central vision and metamorphopsia in both eyes. His best corrected visual acuity was 20/30 in the right eye and 20/50 in the left eye. Based on fundoscopy, fluorescein angiography, and optical coherence tomography (OCT), the patient was diagnosed with MacTel type 2 combined with stage 1B impending macular hole in both eyes. A phacovitrectomy with internal limiting membrane peeling and fluid-gas exchange with SF6 was performed in both eyes. One week after surgery, an improvement in foveal cysts and foveal defects filled with tissue were observed. However, at 1 month postoperatively, OCT findings showed near complete absence of foveal tissue resembling full thickness macular hole. One year after surgery, this loss of foveal tissue was remained. Conclusions: In our case, the foveal structure over times has changed after vitrectomy for MacTel type 2 with impending macular hole. A case such as ours with long term follow up using OCT imaging postoperatively has not been previously reported. Our surgery failed to be reopened 1 month later. After vitrectomy, we did not find an anatomical success. However, the patient did not experience serious visual decline.
Antibiotic susceptibility of bacteria isolated from patients with diabetes mellitus and recurrent urinary tract infections in Babylon Province, Iraq

Background: The emergence of the antibiotic resistance in the treatment of UTIs is a serious health problem, especially in the developing countries where there is high level of ignorance, poverty, and bad hygienic practices, Objective: The aim of this study was to detect the types of bacteria and their antibiotic sensitivity in patients with diabetes mellitus with recurrent urinary tract infections and compare between types of bacteria in patients with the previous admission to hospital from those who are not. Materials and Methods: This cross-sectional study was conducted on eighty patients with diabetes mellitus and recurrent urinary tract infection, those patients who visited the Outpatient Unit in Diabetic and Endocrine Center in Merjan Medical City in Babylon Province. This study was carried out from March 1, 2016 to September 30, 2016. General urine examination was done to the patient with urinary tract infection. Urine samples were sent for culture and sensitivity against different types of antibiotics. Results: Results found that the mean age of the patients was (58.23 ± 14.38) and majority of them (63.7%) were female and (52.5%) of them came from rural area. The main bacteria causing urinary tract infection was Escherichia coli in more than 55% of cases, while the amikacin antibiotic regard as the best antibiotic in the treatment of urinary tract infection in this study with lowest resistance percentage (3.8%). Based on the history of previous admission to the hospital, there was 57.5% with a history of previous admission, and there was statistically significant difference in the types of bacteria between the two groups. Conclusion: There was significant difference in bacterial type between patients who previously had hospital admission and those who had not. E. coli was the main bacteria causing UTI in this study. Amikacin showed the best sensitive drug for bacteria that cause urinary tract infection.
International Studies of Infarct Survival (ISIS)

The International Studies of Infarct Survival (ISIS) began in 1981 as a collaborative worldwide effort to evaluate the effects of several widely available and practical treatments for acute myocardial infarction. Coordinated in Oxford, England, over 20 countries have participated in the ISIS trials. To date, the ISIS Collaborative Group has randomized over 134,000 patients into four large simple trials assessing the independent and synergistic effects of beta-blockers, thrombolysis, aspirin, heparin, converting enzyme inhibitors, oral nitrates, and magnesium in the treatment of evolving myocardial infarction (Table 1).