Miracle-dz/UniFAR-FTUs huggingface dataset:
Analyzing Discourse Coherence in Bengali Elementary Choras (Children’s Nursery Rhymes)

The present paper aims to explain the process of meaning making in Bengali elementary Choras (children’s nursery rhymes) by their intended target audience, little children, who are yet to develop their semantic, cognitive or linguistic skills. Chora, the Bengali oral folkloric counterpart of nonsensical verses for children, can be characterised as a type of dynamic discourse where socio-cultural elements occur abundantly though asymmetrically. Outlined by intermittent cohesive gaps, such discourses are however found to be thoroughly enjoyed and appreciated by the little children, despite their lack of prior textual and/or contextual awareness. Following this, it is observed that such rhymes or Choras are more about experiencing amusement that the children derive from the verses rather than understanding their denotative or connotative sense. Meaning making of such rhymes by the little children, we claim, occur not through the processing of semantics of the text but by directly experiencing the communicative intent of the discourse. Coherence of such dynamic and discontinuous discourses is therefore attained when their pragmatic intent, that is enjoyment intertwined in the verses, is identified by the little children and reciprocated through affirmation. The analysis detects the predominance of coherence constructed at the discourse level and accordingly the methodology adopted to explain cognizance in elementary Choras is the theory of Discourse Coherence (Wang and Guo, 2014) which claims that coherence in discourse can be achieved jointly by the discourse producer as well as the receiver.
A projection-pursuit method for sparse robust pca

A method based on the idea of projection-pursuit is introduced for obtaining principal components that are robust and sparse [3]. The term robust refers to resistance against outlying observations, while the expression sparse means that some of the principal component loadings will be forced to zero values. In that way, the resulting method is insensitive to outliers in the data, and due to the sparse loading pattern, results are simpler to interpret.
A Novel Halogen Bond Acceptor: 1-(4-Pyridyl)-4-Thiopyridine (PTP) Zwitterion

Sulfur is a widely used halogen bond (XB) acceptor, but only a limited number of neutral XB acceptors with bifurcated sp3-S sites have been reported. In this work a new bidentate XB acceptor, 1-(4-pyridyl)-4-thiopyridine (PTP), which combines sp3-S and sp2-N acceptor sites, is introduced. Three halogen bonded cocrystals were obtained by using 1,4-diiodobenzene (DIB), 1,4-diiodotetrafluorobenzene (DIFB), and iodopentafluorobenzene (IPFB) as XB donors and PTP as acceptor. The structures of the cocrystals showed some XB selectivity between the S and N donors in PTP. However, the limited contribution of XB to the overall molecular packing in these three cocrystals and the results from DSC measurements clearly point out the synergetic influence and interplay of all noncovalent interactions in crystal packing of these compounds.
Using the life satisfaction approach to value daylight savings time transitions. Evidence from Britain and Germany

Daylight savings time (DST) represents a public good with costs and benefits. We provide the first comprehensive examination of the welfare effects of the spring and autumn transitions for the UK and Germany. Using individual-level data and a regression discontinuity design, we estimate the effect of the transitions on life satisfaction. Our results show that individuals in both the UK and Germany experience deteriorations in life satisfaction in the first week after the spring transition. We find no effect of the autumn transition. We attribute the negative effect of the spring transition to the reduction in the time endowment and the process of adjusting to the disruption in circadian rhythms. The effects are particularly strong for individuals with young children in the household. We conclude that the higher the shadow price of time, the more difficult is adjustment. Presumably, an increase in flexibility to reallocate time could reduce the welfare loss for individuals with binding time constraints. JEL classification: H41, I31
Data Visualization for Statistical Analysis and Discovery in Container Surface Characterization at the Nano-Scale and Micro-Scale

Visualization is used for stainless steel container wall and lid cross section characterization. Two specific types of containers are examined: 3013 and SAVY. The container wall examined is from a sample of the inner container of a 3013 container. The inner lid cross section examined is from a SAVY container. Laser confocal microscope data and photographic data are used to determine features of the surfaces. The surface features are then characterized by various feature statistics, such as, maximum depth, area, eccentricity, and others. The purpose of this pilot study is to demonstrate the effectiveness of using the methodology to detect potential corrosion events on the inner container surfaces. The features are used to quantify these corrosion events. An automatic image analysis system uses this methodology to classify images for possible further human analysis by flagging possible corrosion events. A manual image analysis methodology is used to determine the amount of MnS on the SAVY container lid cross section. Visualization is an integral component of the analysis methodology.
Targeting the Genetic and Molecular Role of ABCG2 Following Traumatic Brain Injury

Traumatic brain injury (TBI) is a leading cause of death and disability. Despite its overwhelming burden on sufferers, their families, and the health-care system; there are no pharmacologic treatments that improve long term clinical outcomes. Drug development for TBI has focused on mitigation of factors that contribute to the persistent secondary injury from TBI. These target reactive oxygen species generation, cerebral edema, excitotoxicity, among others. Genomics has been a productive area to support TBI drug development, and pharmacogenomics (PGx) - based drug use and development has gained utility in critical care and TBI. This helps to identify new targets for treatment and/or prognostication, and to provide targeted therapy based on an individual's genomics. Our objective was to evaluate the role of drug transporters, particularly the ATP-Binding Cassette transporter, ABCG2, following severe TBI. We measured expression of transporters in experimental TBI, evaluated the association of a missense genetic variation in ABCG2 with clinical outcomes from TBI, and studied the change in disposition of the ABCG2 substrate, uric acid (UA), in patients with TBI. We found that overall transporter expression tended to decreased acutely following TBI, exemplified by ABCG2 expression, which was significantly decreased early following injury with a rapid return to baseline. The missense variation in the ABCG2 gene, c.421C>A, was found to be associated with improved outcomes following severe TBI in younger patients, suggesting that ABCG2 dysfunction is neuro-protective. Finally, we discovered that patients with severe TBI who carry a variant allele at ABCG2 c.421C>A have measurable decrease in UA transport in the CNS. These findings suggest that UA is protective following TBI, which may be related to its role as an antioxidant.Future study in this area can include further development of animal models for TBI that can mimic human levels of UA, which are about 10-fold higher in humans than in most other mammals. They may also include prospective observational trials to validate the findings of UA's association with ABCG2 and outcomes. Clinical trials of therapeutic UA or the UA precursor, inosine, may also be warranted in patients suffering from severe TBI.
Non-Nodal CD5-Negative Mantle Cell Lymphoma with Secondary TP53 Deletion

Mantle cell lymphoma is a non-Hodgkin lymphoproliferative neoplasm with several clinical and morphologic variants linked, primarily, through genetic derangement of the cyclin D1 locus. Aberrant phenotypes have been described, though prognostic data in such cohorts are limited due to a paucity of cases. We report a case of mantle cell lymphoma with non-nodal clinical presentation, aberrant loss of CD5 expression, and concomitant cytogenetic deletion of 17p. While non-nodal disease is often associated with an improved prognosis in mantle cell lymphoma, this 67-year-old patient experienced a more challenging clinical course with a poor initial response to chemotherapy. Therefore, this case may represent a type of non-nodal mantle cell lymphoma with a prognosis similar to that of classical cases due to the additional phenotypic and genetic alterations found in this patient.
Effects of 17β-Estradiol on the Plasminogen Activator System in Vascular Smooth Muscle Cells Treated with Lysophophatidylcholine

Objectives When administered soon after menopause, hormone therapy can prevent coronary heart diseases in women. To explore the mechanism underlying the cardioprotective actions of estrogen, we investigated the effects of 17β-estradiol (17β-E2) on the plasminogen activator system using cultured vascular smooth muscle cells (VSMCs). Methods VSMCs were isolated from rat aortas. Protein expression of plasminogen activator inhibitor type 1 (PAI-1) and tissue-type plasminogen activator (t-PA) were evaluated using Western blotting and enzyme-linked immunosorbent assay, respectively. The enzyme activity of PAI-1 in a conditioned medium was assessed via reverse fibrin overlay zymography and that of t-PA was assessed via fibrin overlay zymography. Gene expression was quantified using real-time reverse transcription-polymerase chain reaction. Results Following pre-treatment for 24 hours, 17β-E2 suppressed both protein expression and enzyme activity of PAI-1 stimulated by lysophosphatidylcholine (lysoPC) in a significant and dose-dependent manner at a near physiological concentration. Moreover, 17β-E2 (10−7 M) inhibited PAI-1 gene expression, and ICI 182,780—a specific estrogen receptor antagonist—blocked the effects of 17β-E2 on the PAI-1 protein. 17β-E2 did not affect t-PA secretion but significantly enhanced free t-PA activity through reduced binding to PAI-1. Furthermore, 17β-E2 suppressed intracellular reactive oxygen species production and nuclear factor-κB-mediated transcription. Conclusions In VSMCs stimulated with lysoPC, 17β-E2 reduced PAI-1 expression through a non-receptor-mediated mechanism via antioxidant activity as well as a receptor-mediated mechanism; however, it did not alter t-PA secretion. Of note, 17β-E2 suppressed PAI-1 activity and concurrently enhanced t-PA activity, suggesting a beneficial influence on fibrinolysis.
Cold Science Meets Hot Weather: Environmental Threats, Emotional Messages and Scientific Storytelling

Science is frequently called upon to provide guidance in the work towards sustainable development. However, for science to promote action, it is not sufficient that scientific advice is seen as competent and trustworthy. Such advice must also be perceived as meaningful and important, showing the need and urgency of taking action. This article discusses how science tries to facilitate action. It claims that the use of scientific storytelling—coherent stories told by scientists about environmental trajectories—are central in this; these stories provide meaning and motivate and guide action. To do this, the storylines need to include both a normative orientation and emotional appeals. Two different cases of scientific storytelling are analyzed: one is a dystopic story about a world rushing towards ecological catastrophe, and the other is an optimistic story about a world making dramatic progress. These macrosocial stories offer science-based ways to see the world and aim to foster and guide action. The article concludes by stating that using storylines in scientific storytelling can elicit fear, inspire hope, and guide action. The storylines connect cold and distant scientific findings to passionate imperatives about the need for social transformation. However, this attachment to emotions and values needs to be done reflexively, not only in order to create engagement with an issue but also to counteract a post-truth society where passionate imperatives go against scientific knowledge.
AN ICT BASED COGNITIVE BEHAVIOUR IN THE DOMAIN OF PSYCHOLOGY

The scientific domain in which cognitive science is used for the process of simulation, inference, analysis, function and studies of several aspects of human behaviour such as logics, memory, thinking, learning, perception, solving problems, knowledge and language. The science of study called as e-psychology is in close operational relation with the cognitive science domain but has an efficient collaboration of psychology and Information and Communication Technologies (ICTs). Several features offered with an effective usage of ICTs in several areas such as assessment, counselling, tests, diagnosis, therapy etc., the following document aims at giving the readers a flexible, easy and an adaptable form which supports all psychological activities by the usage of information and all communication tools and mediums.
AN INVESTIGATION INTO THE IMPACTS OF THE TECHNICIANS’ SKILLS GAP ON THE DEVELOPMENT OF THE NIGERIAN CONSTRUCTION INDUSTRY

This study investigates the effect of the technicians’ skills gaps and its impact on the building construction industry development in Nigeria. The technicians’ skills gaps are considered critical in terms of the industry performances particularly in the workforce efficiency. This has led to poor performances of the industry in its competences and productivity, which affected the nation’s economy. The paper critically assessed the technicians’ skills gaps and most appropriate training on the output of the industry performances. Hence, identify the factors that negate growth in technicians’ skills within the industry. The research method for this study is quantitative enquiry, through empirical literature and questionnaire survey. The questionnaire survey received 73% participants’ response rate. These Participants are Project Managers, Technicians and Trainers within the Nigerian construction industry in Abuja Metropolis. Collected data was analysed using content means and frequency analysis, descriptive analysis. The findings of this study indicate that there are great demands for skilled workforce within the industry. More so, behavioural issues may exist between the employers and employees, which negate proper construction practices. This suggests that technicians’ skills training and development is necessary for the industry to achieve effective output for its future growth.
Denitrification performance and kinetics of an attapulgite lightweight ceramsite biofilter

Operating costs and nitrogen removal performance are the most critical aspects of biological nitrogen removal technologies. Here, an attapulgite clay lightweight ceramsite (ACLC) was successfully prepared and combined with a denitrifying biofilter (DNBF) to cost-effectively treat nitrogen-contaminated water. Scanning electron microscopy and Fourier transform infrared spectroscopy were used to characterize the ACLC. Bacteria adhered easily to the ACLC, and biofilm formation was rapid. ACLC density was close to that of water; ACLC floated on the water surface. The optimal parameters of the DNBF were as follows: a hydraulic load of 2.0 m3/(m2 h), a carbon to nitrogen ratio of 4:1, and an anhydrous sodium acetate carbon source. With these optimal parameters, the efficiency of removal of total nitrogen and NO3-N were 87% and 90%, respectively, and the accumulation of NO2–N concentration was 0.18 mg/L. The recovery speed of the DNBF after backwashing, as well as after 3 and 6 d outages, was rapid: only 6 h. The biological denitrification kinetics of the DNBF indicated that a first-order reaction more accurately described the DNBF denitrification process, with a correlation coefficient (R2) of 0.993.
Spinal Descompression Trhough a Tubular System with Assisted Endoscopy

Endoscopic surgery has become an important tool in spinal surgery, the ergonomic design and the required length of the instruments, as well as the use of video monitors greatly affect our perception and performance. Some experts are resistant to the use of the endoscope in spinal surgery, because of the limitations in the perceptual information and that this can lead us to commit incorrect actions during the surgical procedure. Since the introduction in 1997 by Smith and Foley of a system consisting of progressive tubular dilators (MED) to later place an endoscopic vision system, the technique has become increasingly popular to this day. Based on this, other authors have documented the use of this endoscopic tubular system called Easy-Go reporting good results, so the authors of this article focus on the intraoperative peculiarities, experience, first impressions and the technical note of this system. (EASY-GO).
EFFECT OF DIETARY ENERGY LEVELS WITH OR WITHOUT SELENIUM AND CHOLINE SUPPLEMENTATION ON PERFORMANCE OF BROILER CHICKENS.

his research was conducted to study the impact of using two levels of ME (recommended (R) and R-150 Kcal/Kg diet) and each with four type of addition (without Se or choline supplementation, 0.1 mg Se/Kg diet in the form of organic Se as Sel-Plex (Se yeast), 0.10% of choline and 0.05 mg Se/Kg diet + 0.05% choline in 2 x 4 factorial arrangement (giving eight dietary treatments) on growth performance of Cobb broiler chickens. Accordingly, a total number of 192 one-day old unsexed Cobb broiler chickens were firstly fed a control diet for five days. At six day of age, chicks were randomly allotted to the dietary treatments, birds were divided into eight treatments (24 birds each) and each treatment contained three replicates (eight birds each). Results obtained could be summarized in the following:
RUMEN FERMENTATIONS AND RUMEN CILIATE PROTOZOA OF GOAT KIDS FED DIETS WITH DIFFERENT CONCENTRATE: ROUGHAGE RATIO

A growth trail was carried out to determine the effect of feeding rations with different levels of concentrate: roughage ratio on rumen development through examining the rumen fermentation and the identification and density of rumen ciliate protozoa for sequence five months. Eighteen early weaned Balady male goats with an average live body weight about 7.58 kg at 60 days age were randomly allocated in three groups (6 lambs each) according to body weight. The three groups were fed starter pelleted consists of different concentrate: roughage ratios (T1; 90:10, T2; 80:20 and T3; 70:30). Results showedthat rumen parameters concentration and ruminal ciliate protozoa count were significantly increased (P≤0.01) from the age of 8 weeks till the age of 24 weeks. Also, the data indicated that ruminal pH values and ruminal ciliate protozoa count were higher (P≤0.01) before feeding then it decreased at 3 hours post feeding followed by gradually increased, although total volatile fatty acids, ammonia nitrogen, non-protein nitrogen, total nitrogen and true protein nitrogen concentrations reached the highest (P≤0.01) value at 3hr post-feeding then decreased gradually. Seven species of ruminal protozoa were identified in this study, Entodinum spp was the most dominant specie. Comparison among the three experimental treatments showed that T3 had the highest (P≤0.01) concentrations of rumen parameters and ruminal ciliate protozoa count during the whole period followed by T2, while T1 had the lowest (P≤0.01) values. So we recommended involving high roughage ratio in goat kids feeding.
Vulval Intestinal/Enteric Heterotopia in a Patient with Crohn's Disease

Intestinal/enteric heterotopia of the vulva is an extremely rare disease with only 3 cases described in the literature. We report here an unusual case of this disease occurring in a 26-year-old patient in a context of Crohn's disease. To the best of our knowledge, such type of association has not been previously described. The potential origins of these lesions including metaplastic transformation, dysontogenetic changes, or epithelial colonic displacement/implantation are discussed.
DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway

Epithelial-mesenchymal transition (EMT) is a cellular process in which epithelial cells are partially transformed into stromal cells, which endows the polarized epithelium cells more invasive feature and contributes cancer metastasis and drug resistance. Ferritinophagy is an event of ferritin degradation in lysosomes, which contributes Fenton-mediated ROS production. In addition, some studies have shown that ROS participates in EMT process, but the effect of ROS stemmed from ferritin degradation on EMT has not been fully established. A novel iron chelator, DpdtC (2,2′-di-pyridylketone dithiocarbamate), which could induce ferritinophagy in HepG2 cell in our previous study, was used to investigate its effect on EMT in gastric cancer cells. The proliferation assay showed that DpdtC treatment resulted in growth inhibition and morphologic alteration in MGC-803 cell (IC50 = 3.1 ± 0.3 μM), and its action involved ROS production that was due to the occurrence of ferritinophagy. More interestingly, DpdtC could also inhibit EMT, leading to the upregulation of E-cadherin and the downregulation of vimentin; however, the addition of NAC and 3-MA could attenuate (or neutralize) the action of DpdtC on ferritinophagy induction and EMT inhibition, supporting that the enhanced ferritinophagic flux contributed to the EMT inhibition. Since the degradation of ferritin may trigger the production of ROS and induce the response of p53, we next studied the role of p53 in the above two-cell events. As expected, an upregulation of p53 was observed after DpdtC insulting; however, the addition of a p53 inhibitor, PFT-α, could significantly attenuate the action of DpdtC on ferritinophagy induction and EMT inhibition. In addition, autophagy inhibitors or NAC could counteract the effect of DpdtC and restore the level of p53 to the control group, indicating that the upregulation of p53 was caused by ferritinophagy-mediated ROS production. In conclusion, our data demonstrated that the inhibition of EMT induced by DpdtC was realized through ferritinophagy-mediated ROS/p53 pathway, which supported that the activation of ferritinophagic flux was the main driving force in EMT inhibition in gastric cancer cells, and further strengthening the concept that NCOA4 participates in EMT process.
Abstrak. Selulosa dari sekam padi telah berhasil disintesis. Sekam padi merupakan limbah pertanian yang melimpah dan mempunyai kandungan selulosa yang cukup tinggi. Biokonversi sekam padi menjadi selulosa diawali dengan tahapan proses delignifikasi dan bleaching. Selulosa yang dihasilkan dikarakteri

Cellulose from rice husk has been successfully synthesized. Rice husk is an abundant agricultural waste and has a high cellulose content. Bioconversion of rice husk into cellulose begins with the stages of delignification and bleaching. The resulting cellulose was characterized using FTIR and XRD. The IR spectra show a strong absorption peak at 3444.87 cm 1 which is associated with stretching vibrations O − H (hydrogen bonds between molecules), an absorption peak at 1033.85 cm 1 is identified as stretching C − O − C which is β bond −1,4 glycosidic from cellulose. X-ray diffragtogram showed that te cellulose obtained had a particle size of 3.44 nm and crystallilnity of 58.73%. These results indicated that cellulose from rice husk had good characteristics.