Miracle-dz/UniFAR-FTUs huggingface dataset:
An improved Recycling Nested Miller Compensation Amplifier with High Gain-Bandwidth

— During the past decades, multi-stage amplifiers have been studied and designed to achieve better performance. According to contemporary circuit topologies, the traditional multi-stage amplifier can only achieve low gain-bandwidth (< 5 MHz) and a low slew rate (< 10 V/μs). In this paper, an improved recycling nested Miller compensation (IRNMC) amplifier is presented. By applying recycling folded cascode topology as the first stage amplifier, the proposed IRNMC amplifier improved the performance of gain-bandwidth and slew rate over that of the current multi-stage amplifiers. The proposed IRNMC amplifier is implemented in the TSMC 0.18- μm CMOS process, and is simulated using a 1.8 V power supply with a load capacitor of 100 pF. Simulation results show that the proposed IRNMC amplifier achieved a 137dB DC gain, a 15 MHz gain- bandwidth, a 62° phase margin and a 14.6 V/μs slew rate.
ROLE OF PLANT GROWTH REGULATORS IN PETAL SENESCENCE OF CALENDULA OFFICINALIS L. AND COREOPSIS LANCEOLATA L.

Freshly cut flowers of Calendula as a detached system and flowers of Coreopsis in an intact system were taken to carry out a comparative study of petal senescence. Changes in proteins, amount of sugars and MDA (Malondialdehyde) content were estimated with the advancement of flower senescence. Activities of peroxidase and protease registered a steady increase during 0 to 8-day and 0 to 16-day in C. officinalis and C. lanceolata respectively. Higher concentration of each plant growth substance was effective to slow down the enzymatic activity and reduced the degradation of various metabolites. The distribution pattern of sugars and degree of effectiveness of growth regulators were not identical in these two flowers. The overall order of effectiveness among the applied plant growth regulators was KN> SA> MOR in both the flowers.
Die Beteiligung der Peroxisomen am Lipidstoffwechsel

1. Peroxisomen kommen ubiquitar in Saugetiergeweben vor. Sie zeichnen sich durch ihren Gehalt an Katalase und an Wasserstoffperoxid bildenden Oxidasen aus. % 2. Eine dieser Oxidasen, die Fettsaureacyl-CoA-Oxidase ist das erste Enzym eines speziellen Fettsaures-Oxidationssystems der Peroxisomen, das langkettige Fettsauren verkurzt; der vollstandige Abbau der entstandenen mittleren Fettsauren wird von den Mitochondrien besorgt. Peroxisomen haben die Fahigkeit, sehr langkettige Fettsauren und rra/w-ungesattigte Fettsauren, wie sie sich in hydrierten Olen finden, dem Abbau zuzufuhren.
Studying genetic relationships among tea (Camellia sinensis L.) cultivars in Sri Lanka using RAPD markers

Genetic variability is one o f the key factors, which decide the success o f a plant-breeding programme. Therefore, it is important for the plant breeder to identify the sources o f genetic variabil ity in the available germplasm and thereafter, exploit the variability, which promotes the effective conservation and sustainable util ization o f plant genetic resources. Molecular makers offer several new possibilities for accessing genetic variability. I n the present study, genetic relatedness o f 39 Sri Lankan tea {Camellia sinensis L. ) cultivars was assessed by Random Ampl i f ied Polymorphic D N A ( R A P D ) m a r k e r technique. Twenty R A P D primers that produced consistent amplifications were selected and used for this study to generate 223 polymorphic markers. A considerable range o f genetic diversity (genetic distances ranging between 0 .17-0 .38) was observed with an average genetic distance o f 0.37. In both ' T R I cultivars' and 'Estate selections' not much diversity was found between (0 .38 ) or within two groups (0.35 and 0.33 respectively). Two phenotypically distinct cultivars, 'Yabukita' and 'China' varied significantly from both ' T R I cultivars' and 'Estate selections'. Furthermore, ' T R I 7 7 7 ' , ' T R I 2 0 1 6 ' and ' T R I 4 0 0 6 ' cultivars demonstrated a higher degree o f genetic divergence. ' T R I 7 7 7 ' showed closer relationship to estate selections (0 .39) than to T R I developed cultivars (0 .42) . Furthermore, although ' T R I 7 7 7 ' clustered with 'China ' and 'Yabuki ta ' , it was considerably genetically different from both 'Yabukita ' ( 0 .45 ) and 'China' (0 .46) . Cultivars ' T R I 2 0 1 6 ' , ' T R I 4 0 0 6 ' , ' T R I 7 7 7 ' , 'China ' and 'Yabukita ' have been identified as progenitors that could be very effective in generating heterosis in the breeding programmes. Whi le the clear separation o f ' T R I cultivars' and 'Estate selections' into two distinct clusters in the dendrogram confirmed most o f their origins, the sub clusters within the main clusters conformed nicely wi th their parentages and historical pedigree records. K e y words: Camellia sinensis L. , Conservation, Diversity, Molecular markers, R A P D , Tea.
Site-directed mutagenesis of PsaA:M684 in Chlamydomonas reinhardtii

The electron transfer chain of PSI comprises a primary electron donor (P700; chlorophyll a dimer), and five electron acceptors: A0 (chlorophyll a monomer); A1 (phylloquinone); FX; FA and FB (all 4Fe4S2- centres). P700 and FX exist on the apparent C2 axis of symmetry of the PsaA/PsaB heterodimeric core, and there are two symmetrical branches of the redox cofactors A0 and A1 between them. It has recently been suggested that both branches of electron transfer may be functional, with a fast branch (PsaB branch) and a slow branch (PsaA branch) [1]. We have been using a combination of site-directed mutagenesis and spectroscopy to probe the protein environment surrounding the cofactor, A0. The suggested ligand to the central magnesium of the chlorophyll A0 is residue M684 on the PsaA polypeptide of PSI. The presence of a methionine residue as a ligand to a chlorophyll is highly unusual. We have been studying the effect of mutating this residue in the unicellular green alga, Chlamydomonas reinhardtii, on the dynamics of electron transfer in PSI and the properties of A0. The analysis of the mutants (M684A, M684H and M684V) has been carried out using paramagnetic spectroscopic techniques. These techniques have enabled us to investigate whether residue PsaA:M684 is a factor controlling the redox potential of A0. Inactivation of electron transfer on the PsaA branch in some of these mutants has enabled study of the significance of bidirectional electron transfer in PSI. 1. Guergova-Kuras, M. , Boudreaux, B. , Joliot, A. , Joliot, P., Redding, K. (2001) PNAS, in press.
PLASMA FAT PARAMETERS IN THE FERAL PIGEON (COLUMBA LIVIA F. URBANA) DURING ITS POSTEMBRYONIC DEVELOPMENT

Plasma fat parameters in the young Feral Pigeons were investigated. The body mass, triglycerides, total cholesterol and lipoprotein fractions HDL and LDL were examined. In the initial period of postembryonal development the body mass of Feral Pigeons increased intensively and later it was stabilised. Concentrations of triglycerides and cholesterol did not show any age-related changes, however HDL fraction increased and LDL fraction decreased with age.
Life after cold death: reef coral and coral reef responses to the 2010 cold water anomaly in the Florida Keys

Organismal and community-wide responses of reef-building corals are documented before and after a severe cold-water thermal anomaly that occurred in 2010 in the Florida Keys, USA. In January 2010 seawater temperatures dropped far below the normal minima (to 80%) on inshore reefs. In contrast, another common coral with a wide thermal tolerance, Siderastrea siderea, was not affected by this cold anomaly. We measured biomass, symbiotic algal densities (genus: Symbiodinium), chlorophyll a content, and maximum quantum efficiency of photosystem II for reef-building corals on a seasonal basis before and after the 2010 cold anomaly. Our data document a clear correspondence between physiological response, biomass levels, and survivorship among these five scleractinian coral species. These physiological findings are mirrored by in-shore benthic community monitoring data, which show the dramatic loss of the three cold-sensitive species and continued survival of the cold-tolerant species. Finally, we document recruitment and survival rates of newly settled reef-building corals on four inshore reefs, which experienced high coral mortality during the 2010 cold-kill. Interestingly, both a cold-tolerant species, S. siderea, and a cold-intolerant species, P. astreoides, were the most abundant species recruiting to these postdisturbance reefs.
Identification Of Silymarin In Echinopus tenuisectus Family Compositae

This study emphasized on the detection and identification of silymarin (Silybinin) Flavonoid in a newly studied, wild Iraqi plant, named Echinopus tenuisectus of Compositae family. The medicinal importance of silymarin on the one hand, and the absence of any phytochemical investigation on tenuisectus specie of Echinopus genus on the other hand, acquired this study its importance. Silymarin was identified in the plant extract of both, the aerial part’s and the seed’s extracts, by two chromatographic methods, first Thin Layer Chromatography (TLC) using TLC ready made Gf254 plates, UV detector at 254 nm, and three different solvent systems in which the Rf value of the standard silymarin matched with the Rf value of the plant extract silymarin. HPLC was the other chromatographic method that proved the presence of silymarin in the plant extract by identical retention times. The result indicated that the silymarin content in the seed extract was higher than that in the plant extract of the aerial parts. صلختسملا ىمسم Echinopus tenuisectus ة فنصل ةیئایمیكلا تانوكملا لوانتت ةیملع tenuisectus سنجل Echinopus ، اھتیمھأ ةساردلا ةذھ تذخأ . مت لك يف نیرامیلیسلا ةدام نع فشكلا ةیولعلا ءازجلال تابنلا صلختسمو روذبلا صلختسم نم ، نیتقیرط ةطساوب ةیفارغوتاموركلا قرط نم ، ةیفارغوتاموركلا ةینقت يھ ىلولأا ةقبطلا ةقیقرلا TLC TLC تاذ ةیعونلا Gf254 ةیجسفنبلا قوق ةعشلاا فشاكو U.V 254 ةمیق نا Rf ةمیق تقباط ةیسایقلا نیرامیلیسلا ةدامل Rf . يتابنلا صلختسملا يف نیرامیلیسلا ةدامل ةقیرط HPL
Review in Utilization of Insect Natural Enemies during the Period from 1985 to 2015 in China(Part 2)

The utilization of insect natural enemies from 1985 to 2015 in China is reviewed in this paper. The articles published in the Chinese Journal of Biological Control are referenced specially by author. The five fields in utilization of insect natural enemies are included as following: the survey of insect natural enemy resource, mass rearing and augmentation, basic searches related to rearing and release, successful cases in introduction of exotic parasitoids, strategies of biological control in pest insects control. Hopefully, it could be a brief summary in utilization of insect natural enemies for the past 30 years in China. This paper is divided into two parts for publication. The basic searches related to rearing and release, successful cases in introduction of exotic parasitoids and strategies of biological control in pest insects control are consist in this second part. The rest content is in the first part.
Nitrogen transport in plants, with an emphasis on the regulation of fluxes to match plant demand

Physiological methods, especially the use of isotopes of N, have allowed for the detailed characterizations of the several putative transport systems for nitrate and ammonium in roots of higher plants. In the last decade, the cloning of genes that appear to encode both high- and low-affinity transporters represent major advances, as well as substantiating the inferences based on earlier physiological methods. Nevertheless, the unexpected plethora of genes that have been identified now presents even greater challenges, to resolve their individual functions and to attempt to place these functions in a whole plant/environmental context.
Safety of lactic acid bacteria and their occurrence in human clinical infections

Les bacteries des genres Lactobacillus, Leuconostoc, Pediococcus et Bifidobacterium sont largement utilisees dans l'industrie agro-alimentaire, et leur usage empirique pour la conservation et la transformation des aliments est immemorial. Ces bacteries, pour la plupart commensales de l'homme, ont cependant ete isolees dans de rares cas d'infections, principalement: (1) d'endocardites essentiellement a Lactobacillus (53 cas publies depuis 1938) survenant, plus souvent qu'avec les autres bacteries, sur atteinte valvulaire prealable et avec une porte d'entree buccale frequente; (2) de bacteriemies a Lactobacillus ou a Leuconostoc (0,1% et 0,01% respectivement des hemocultures positives en France), a Pediococcus ou a Bifidobacterium, bacteriemies associees ou non a (3) des foyers locaux qui peuvent eux-memes se developper en absence de bacteriemies
Liposomes for the delivery of nucleotides and oligonucleotides

L'adenosine triphosphate (ATP) et les oligonucleotides antisens sont des molecules tres polaires, chargees negativement et penetrant en tres faible quantite a l'interieur des cellules. En outre, l'ATP et les oligonucleotides sont instables en milieu biologique. Neanmoins, ces deux molecules sont responsables d'importants effets biologiques qui peuvent etre utilises en therapeutique. L'ATP, comme substrat energetique, peut etre utilisee dans de nombreuses applications medicales et les oligonucleotides antisens, capables d'inhiber l'expression genetique, peuvent etre appliquees au traitement des infections virales et des tumeurs induites par des oncogenes. Afin de concevoir un systeme capable de proteger les nucleotides et oligonucleotides contre la degradation et de les liberer efficacement au niveau intracellulaire, l'encapsulation des liposomes a ete envisagee. L'objectif de cette revue est de resumer l'activite de notre groupe dans l'utilisation des liposomes d'ATP pour le traitement de l'ischemie cerebrale et l'amelioration de la mobilite des spermatozoides. Nous montrons aussi l'interet de l'utilisation de liposomes pH-sensibles contenant des oligonucleotides antisens diriges contre l'ARNm du retrovirus de Friend.
Parmelia barrenoae and P. pinnatifida, Two Lichen Species New to Poland

Abstract: Ossowska, E. & Kukwa, M. 2016. Parmelia barrenoae and P. pinnatifida, two lichen species new to Poland. — Herzogia 29: 198–203. Parmelia barrenoae and P. pinnatifida are reported as new to Poland. Parmelia barrenoae is known from 85 records and is widely distributed throughout Poland. Parmelia pinnatifida, by contrast, is a rare species recorded only in mountain areas. The general distribution of both species, their habitat requirements, morphology, secondary chemistry, and differences compared to similar taxa are discussed.
Relation between Water Stress and DNA Synthesis during Germination of Zea mays L.

Mitotic index, percent nuclei in DNA synthesis and the relative DNA content per nucleus were determined from cells of the Zea mays radicle at various times after the beginning of germination. Nuclear DNA synthesis was initiated after 45 h and mitosis was first observed after 74 h from sowing. Most of the dormant nuclei were in the pre-synthetic or Gx phase of the mitotic cycle. By 72 h most cells were in S and 77 h after the beginning of germination, the cells of the primary root were observed in all phases of the mitotic cycle. Dehydration of karyopses after 45-74 h of imbibition progressively reduced the percent of germination to zero upon dehydration and subsequent replanting demonstrating that drought sensitivity was related to the onset of nuclear DNA synthesis and genome duplication.
Microbiological Flora of Aquacultured Hybrid Striped Bass.

Aquacultured hybrid striped bass were examined for quantity and quality of microflora. Plate counts were performed at three temperatures (7, 22, and 35°C) under aerobic and anaerobic conditions. Bacterial loads on the skin, gills, and intestines were similar to those reported for wild fish. Plate counts performed at 22°C yielded the highest counts and the greatest variety of species. The predominant groups of bacteria isolated were Aeromonas spp. (27%), coryneforms (14%), Pseudomonas spp. (12%), Flavobacterium/Cytophaga/Sphingobacterium group (8%), Plesiomonas shigelloides (7%), Bacillus spp. (7%), and Enterobacteriaceae (6%). Human foodborne pathogens Listeria monocytogenes , Staphylococcus aureus , Shigella dysenteriae , Vibrio spp. , and Yersinia pseudotuberculosis were also isolated. There were no indications, however, that pond-raised fish present a higher risk of foodborne illness than do wild fish.
Pituitary hormones and their role in folliculogenesis.

The mechanisms that promote full development of ovarian follicle are complex and not well understood. Different substances act on specifics stages of follicular development to regulate such mechanisms, allowing the activation of primordial follicles, follicular growth, selection of a dominant follicle and ultimately ovulation. Among the substances involved pituitary hormones are highlighted: the gonadotrophins Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH), the Somatotrophin or Growth Hormone (GH) and Thyrotropin or Tireotrophic Stimulating Hormone (TSH), that act direct or indirectly on follicular development and maturation. The gonadotrophins are considered primary regulators of folliculogenesis, providing an almost specific action on the reproductive system. However, there are strong evidences that also indicate an important role of GH and TSH in this regulation. In this regard, this review will present some aspects related to each in vivo and in vitro performance of these hormones (FSH, LH, GH and TSH) on follicular development.
A preliminary comparison of Magnum 116 bodygrip traps with a live capture trap design during the control of grey squirrels (Sciurus carolinensis)

ABSTRACT The grey squirrel is an invasive pest species in the United Kingdom and populations are controlled to protect timber crops and native fauna. Although animals are culled using a variety of methods, there are few data available on the relative efficiency of different trap designs, and in particular spring traps. We compared grey squirrel captures in Magnum 116 spring-traps set within Fineren boxes against captures in a single entry live capture trap design. Trapping was conducted in mature mixed woodland in North Wales. No significant difference in the frequency of grey squirrel captures or body mass of trapped individuals between trap designs was observed. Despite the Fineren box design limiting access by non-target species, by-catch was recorded. We make recommendations for future research to minimise this and also compare our results for Magnum 116 traps with data available on captures in Fenn IV spring traps. The findings have broad relevance to the control of grey squirrels across their wider international invasive range.
Integrin αvβ3 (vitronectin receptor) is a candidate receptor for the virulent echovirus 9 strain Barty

The enterovirus echovirus 9 strain Barty (E9/Barty) is pathogenic for newborn mice as well as for humans. In contrast to the apathogenic prototype strain Hill, strain Barty encodes an RGD motif in the C-terminal part of the structural protein VP1. Data are presented that show that E9/Barty binds its target cells via contact of the RGD motif to the αvβ3 integrin (vitronectin receptor), whereas prototype Hill uses a different, still unidentified receptor site. Furthermore, virus titres of murine muscle tissue were compared after infection of newborn and 1-, 2-, 3- and 12-week-old mice. The replication capacity of the virus decreased dramatically with age of the infected mice. Since E9/Barty does not replicate or replicates only poorly in mice older than about 5 days, and expression of the vitronectin receptor is reported to be down-regulated in striated muscle tissue during development, it is suggested that susceptibility of mice to this echovirus infection is controlled by the availability of αvβ3 integrin.
ANTI MICROBIAL ACTIVITY OF EXTRACTS OF LEAF AND ROOTS OF Embelia tserjiam cottam AGAINST DENTAL PATHOGENS

Natural products today are most likely to exist and grow to become even more valuable as sources of new drug leads. This is because of broader degree of chemical diversity and novelty of molecules found in natural products than that from any other source. The oral cavity provides a diverse environment for colonization by a wide variety of micro organisms. The plant under consideration is reported in the traditional literature for treatment of dental disorders. Thus, the aim of this research work was to evaluate extracts of the investigational plant Embelia tsjeriam cottam against dental pathogens. Ethanolic extracts of leaves and roots of the plant were prepared using Soxhlet extractor. The prepared extracts were subjected to phytochemical screening for different active constituents. Dental pathogens were isolated from cavities and tooth tartar of patients. They were characterised morphologically and the prepared extracts were tested for anti microbial activity against these dental pathogens by cup plate method. The root and the leaf extract showed significant activity at a concentration of 100mg/ml against test dental pathogens. Thus the experimental work showed that the roots and leaves extracts of Embelia tsjeriam cottam have promising antimicrobial activity against dental pathogens thus proving their effectiveness in the treatment of various dental diseases thus confirming the traditional claims.
Contribution to Special Issue: ‘Towards a Broader Perspective on Ocean Acidiﬁcation Research Part 2’ Food for Thought Parasitic infection: a missing piece of the ocean acidiﬁcation puzzle

Ocean acidiﬁcation (OA) research has matured into a sophisticated experimental and theoretical scientiﬁc discipline, which now utilizes mul-tiple stressor, mesocosm experiments, and mathematical simulation models to predict the near-future effects of continued acidiﬁcation on marine ecosystems. These advanced methodological approaches to OA research also include the study of inter-speciﬁc interactions that could be disrupted if participant species exhibit differential tolerances to stressors associated with OA. The host-parasite relationship is one of the most fundamental ecological interactions, alongside competition and predation, which can regulate individuals, populations, and commun-ities. The recent integration of competition and predation into OA research has provided great insight into the potential effects of differential tolerances to acidiﬁed seawater, and there is no reason to believe that expanding OA research to include parasitology will be less fruitful. This essay outlines our current, limited understanding of how OA will affect parasitism as an ecological process, describes potential pitfalls for researchers who ignore parasites and the effects of infection, and suggests ways of developing parasitology as a sub-ﬁeld of OA research.
The β Subunit of Heterotrimeric G Protein Interacts Directly with Kinesin Heavy Chains, Kinesin-I

Kinesin-I exists as a tetramer of two heavy chains (KHCs, also called KIF5s), which contain the amino (N)-terminal motor domain and carboxyl (C)-terminal domain, as well as two light chains (KLCs), which bind to the KIF5s (KIF5A, KIF5B and KIF5C) stalk region. To identify the interaction proteins for KIF5A, yeast two-hybrid screening was performed and a specific interaction with the β subunit of heterotrimeric G proteins (Gβ) was found. G bound to the amino acid residues between 808 and 935 of KIF5A and to other KIF5 members in the yeast two-hybrid assay. The WD40 repeat motif of Gβwas essential for interaction with KIF5A. In addition, these proteins showed specific interactions in the glutathione S-transferase (GST) pull-down assay. An antibody to KIF5s specifically co-immunoprecipitated KIF5s associated with heterotrimeric G proteins from mouse brain extracts. These results suggest that kinesin-I motor protein transports heteroterimeric G protein attachment vesicles along microtubules in the cell.