Miracle-dz/UniFAR-FTUs huggingface dataset:
Reproductive strategies of the crinoid-associated shrimps Cristimenes commensalis (Borradaile, 1915) and Pontoniopsis comanthi Borradaile, 1915 (Crustacea: Palaemonidae)

Tropical shallow-water crinoids offer shelter to a diversity of marine life, including various symbiotic palaemonid shrimp species. In this study, the reproductive features of the shrimps Cristimenes commensalis and Pontoniopsis comanthi inhabiting comatulid crinoids are studied and compared. Ovigerous females were collected from the crinoids Anneissia bennetti and Comaster nobilis from Iriomote-jima, Japan. All specimens were examined for the following traits: carapace length, fecundity, embryo volume, brood mass volume and dry weight of the females and the eggs. Cristimenes commensalis produced 15–117 eggs with a volume of 0.04 mm3 ±0.00, whereas the smaller-sized species P. comanthi produced 12–57 eggs with a volume of 0.02 mm3 ±0.01. The reproductive output (RO) of C. commensalis was 0.16±0.03, considerably lower than that of P. comanthi at 0.31±0.05. Data is beginning to emerge on the fecundity and reproductive output of symbiotic palaemonid shrimps, although comparisons remain hampered by the general lack of knowledge on their biology in general. Pontoniopsis comanthi has the highest recorded reproductive output so far, despite being the smallest species studied. Our results confirm that inhabiting a sheltered habitat allows symbiotic shrimps to allocate more energy to embryo production than free-living species. Different reproductive strategies are, however, apparent for these species inhabiting the same host species, implying the existence of differential selective forces.
Securing Communications in the Quantum Computing Age: Managing the Risks to Encryption

The authors of this report explore the risks posed by the development of quantum computers able to crack digital encryption by assessing how quickly quantum computers are likely to be developed, how quickly postquantum cryptography (PQC) that can withstand attacks is likely to be standardized, and how quickly and widely PQC will be adopted. The analysis concludes that the threat to the communications infrastructure is urgent but manageable.
Skipping Cross Links in Posterior Spine Surgery: A Review

* Corresponding Author: Misagh Shafizad, MD. Address: Orthopedic Research Center, Imam Khomeini Hospital, Sari, Iran Tel: +98 (11) 33377169 E-mail: paper87@yahoo.com Background and Aim: Given the conflicting and unreliable evidence for using cross-links in posterior spine surgery, this review was conducted to highlight the different features and usefulness of these augmentation devices in spine surgeries.
A conceptual framework of virtual team effectiveness from the socio-technical perspective

IMOI model, socio-technical perspective, team effectiveness, virtual team In the era of globalization and technologization, virtual teamwork has become a routine part of professional activity in the software industry and other industries. Understanding virtual team effectiveness helps the management to improve the overall effectiveness of organizations. In this paper, we conduct a literature review of team research to set up a conceptual framework of virtual team effectiveness based on the sociotechnical perspective and Inputs-Mediators-Outputs-Inputs model. Our framework includes some salient inputs, mediators and outputs of virtual team life-cycle; specifically, technology readiness and intention to explore are two technical antecedents; team learning and transactive memory system are two social antecedents; and team performance is a socio-technical output representing virtual team effectiveness. After that, a 27-item measuring instrument of aforesaid concepts is proposed after a qualitative survey of 19 virtual team leaders and a quantitative survey of 151 virtual team members from 19 companies locating in Vietnam. The results are references for those interested in improving virtual team effectiveness.
Fine-scale family structure shapes influenza transmission risk in households: insights from a study of primary school students in Matsumoto city, 2014/15

Background Households are important settings for the transmission of seasonal influenza. Previous studies found that the per-person risk of within-household transmission decreases with household size. However, more detailed heterogeneities driven by household composition and contact patterns have not been studied. Methods We employed a mathematical model which accounts for infections both from outside and within the household. The model was applied to citywide primary school surveillance data of seasonal influenza in 2014/15 season in Matsumoto city, Japan. We compared a range of models to estimate the structure of household transmission. Results Familial relationship and household composition strongly influenced the transmission patterns of seasonal influenza in households. Children had substantially high risk of infection from outside the household (up to 20%) compared with adults (1-3%). Intense transmission was observed within-generation (between children/parents/grandparents) and also between mother and child, with transmission risks typically ranging around 5-20% depending on the pair and household composition. Conclusions We characterised heterogeneity in household transmission patterns of influenza. Children were identified as the largest source of secondary transmission, with family structure influencing infection risk. This suggests that vaccinating children would have stronger secondary effects on transmission than would be assumed without taking into account transmission patterns within the household.
Hur påverkar lednings- och samarbetsförhållanden över organisationsnivåer personalomsättning över tid?

Mot bakgrund av att en hog personalomsattning idag uppfattas som ett problem for sjukvardens verksamhet undersoktes trender av enhetsvis personalomsattning over fem ar och samvariationer med lednings- och samarbetsforhallanden som kan karakteriseras som kravfyllda eller stodjande forhallanden. Resultaten visade att personalomsattningen var hogre for sjukskoterskor och okade for bade underskoterskor och sjukskoterskor. Med klusteranalyser identifierades separata utvecklingsbanor av okande resp. minskande personalomsattning. I de vardenheter som hade minskande trender fanns grundkrav pa eller mojligheter till specialistutbildning for sjukskoterskor samt nagot mindre kravfyllda och mer stodjande organisatoriska forhallanden. Variationen i 5-arsincidens bland sjukskoterskor hade samband med chefers upplevelser av stodjande forhallanden: hogre grad av stodjande organisatoriska strukturer och god samverkan mellan chef och medarbetare minskade personalomsattningen.
Hot brains: A predictive study of game addiction, aggression and self-control

The study has been done to find out whether Game Addiction is a predictor of Aggression and SelfControl. The study is done on adolescents. Gaming Addiction implies the unstoppable urge to play games all day long and it surely affects the daily life of the person. Aggression is a verbal or a physical act which is intended to harm a person. Self-control means the ability of a person to control his temptations, aggression, anger, temper and to stay calm and relaxed in harsh circumstances of life. A sample of 147 (92 males and 55 females) adolescents has been used as population for the study. All of them are students of 11 class and have been taken from Bhiwani city of Haryana state from India. The study uses three questionnaires to collect the data. These are namely Game Addiction Scale, Aggression Questionnaire and Self-Control scale (self report). Three groups were made namely Group 1, Group 2, Group 3 on the basis of scores of game addiction scale and the descriptive statistics show that Group 1 who scored highest on game addiction scale has highest level of aggression and lowest level of self-control. Then Group 1 has been used to test whether Game Addiction predicts Aggression and Self-Control or not. To do so, the study uses regression analysis as a statistical tool. The confidence interval is 95%. The results show that game addiction predicts aggression among adolescents and it is not a good predictor of self-control.
Pengaruh Kemampuan Pembelajaran Organisasional Terhadap Kompetensi Inti Organisasi, dan Kinerja Organisasi Perguruan Tinggi Swasta di Propinsi NTT Suatu Tinjauan Literatur Untuk Membangun Hipotesis Penelitian

Empirically, this paper is expected to see the extent of the development of organizational learning models in the Development of Private Higher Education in the Province of East Nusa Tenggara Province by including the dimensions of the organization's core competencies, and organizational performance in previous strategy research. With the stages of model development which can be seen the contribution and contribution of each previous research to the research carried out mainly in building research hypotheses. In this paper we also want to look gradually at how to understand the partial effect of organizational learning on the organization's core competencies, on diversification strategies and organizational performance. And how all the aspects examined above contribute to further studies in the field of strategy management concerning the effect of organizational learning on core competencies, diversification strategies and organizational performance. The design of this research is mostly done on companies in the field of services in general and some research on higher education organizations. Looking at / reviewing all the studies that have been done by previous researchers whose variables are used as the basis for building and developing hypotheses in this paper, namely, the influence between organizational learning, organizational core competencies and performance. With the following stages begin with searching, separating articles, extracting data, synthesizing data, reporting data. The main contribution in this research is to illustrate that how the construct of organizational learning needs to be developed in improving the organization's core competencies, which in the end is expected to improve the performance of private higher education organizations in NTT Province.
The biological and pharmacological allosteric modulation of inositol monophosphatase

The purpose of this project was to develop novel pharmacological tools against Inositol Monophosphatase (IMPase) and gain new insights into the Calbindin-IMPase interaction. IMPase is an enzyme that has been of significant therapeutic interest since the development of the inositol depletion hypothesis of lithium’s efficacy in the treatment of bipolar disorder. More recent studies have implicated IMPase inhibition in the induction of autophagy and the clearance of peptides involved in the pathogenesis of neurodegenerative diseases. Despite this there is a lack of specific inhibitors and those that have been developed lack favorable physiochemical properties to explore specific IMPase inhibition in vivo. My aim was to find novel inhibiters and binding chemical fragments that could later be developed into potent specific inhibitors of IMPase that would allow for the specific evaluation of IMPase inhibition in vivo. To achieve this, two approaches were tried: first a crystallographic fragment soaking screen was used to identify novel binding sites and chemical matter. This resulted in the discovery of a novel fragment binding site at the homodimer interface and mutagenesis at this site inhibited IMPase activity, indicating that the site could be therapeutically relevant. The second approach was to screen a specially curated isothiazolone library based on the previously identified covalent inhibitor Ebselen. Here I identified a new class of isothiazolone inhibitors of IMPase. The calcium binding protein Calbindin-D28k can allosterically modulate IMPase, this results in the increase in the catalytic activity of IMPase. I aimed to explore this interaction by fusing the proteins using a flexible amino acid linker. The resulting complexes had activity in excess of that of the wild type IMPase, confirming that Calbindin-D28k activated IMPase. Low resolution structural analysis using small angle X-ray scattering (SAXS) revealed a V-shaped IMPase-calbindin complex which was in contrast to the more linear shape predicted by computational docking models. Here we also obtained the first crystal structure of Calbindin-D28k. This crystal structure gave the first direct visualization of the calcium binding sites of the protein and is a better model of Calbindin-D28k in solution than the previous NMR structure.
Relative Risk Premium in China’s Urban Construction Investment Bond: View from Financial Market

This study examines relative risk premium with reference to Urban Construction Investment Bond (UCIB) from the perspective of financial market instrument. We decompose sources of relative risk premium into a spatial layer, and financial instrument level relative risk factor. Based on our research finding, we caution over-prediction on the demise of China’s infrastructure investment and argue that an aggregated view based on stock and flow understates the full potential of the financial market to infrastructure as an emerging asset class. UCIB which remains largely domestic, plays a strategically important role in China’s systems of infrastructure finance and serves as a bridge between China’s emerging capital market and the development of the real economy.
Evaluation of Marginal Bone Level Changes Around Microthreaded Platform Switched Implant in The Aesthetic Zone

Aim: This study was designed to evaluate marginal bone level change around microthreaded platform switched implant in the aesthetic zone. Subjects and methods: Eighteen implant fixture were inserted in 16 patients with missing single tooth in upper anterior area and divided equally into two groups. The patients were selected from those attending outpatient clinic, Oral and Maxillofacial Surgery Department, at the Faculty of Dental Medicine, Boys, Cairo, Al-Azhar University. Clinical examination was made to all patients as: Inspection and palpation of muscles of mastication, tempromandibular joint , lymph nodes, occlusion, condition of the existing teeth and oral mucosa and available inter arch space. Preoperative periapical radiograph as well as, cone beam CT radiograghy for evaluation of the implant site. The patients were assessed clinically at the operative day and post-operatively for 6 months to evaluate implant stability with osstell, Probing depth (PD) and PES/WES score. Marginal bone loss was measured 6 months post-operatively using CBCT radiography. Results: The mean value of vertical bone loss after 6 months was 0.52± 0.15 in group I and 0.92± 0.26 in group II . This bone loss was increased in group II more than group I with statistical significant difference. The mean value of PES/WES total was 13.44± 1.81 in group II and 15.67±1.66 in Group I. This value was decreased in group II more than group I with statistical significant difference. Conclusion: The use of micro threads on the implant neck with platform switch was most effective design to maintain and preserve marginal bone level.
The STROBE: a system for closed-looped optogenetic control of freely feeding flies

Manipulating feeding circuits in freely moving animals is challenging, in part because the timing of sensory inputs is affected by the animal’s behavior. To address this challenge in Drosophila, we developed the Sip-Triggered Optogenetic Behavior Enclosure (“STROBE”). The STROBE is a closed-looped system for real-time optogenetic activation of feeding flies, designed to evoke neural excitation coincident with food contact. We demonstrate that optogenetic stimulation of sweet sensory neurons in the STROBE drives attraction to tasteless food, while activation of bitter sensory neurons promotes avoidance. Moreover, feeding behavior in the STROBE is modified by the fly’s internal state, as well as the presence of chemical taste ligands. We also find that mushroom body dopaminergic neurons and their respective post-synaptic partners drive opposing feeding behaviors following activation. Together, these results establish the STROBE as a new tool for dissecting fly feeding circuits and suggest a role for mushroom body circuits in processing naïve taste responses.
Efficacy of Pluronic F-127 gel containing green tea catechin extract on chronic periodontitis – A clinical study

Purpose: To evaluate the efficacy of pluronic F-127 gel containing green tea catechin extract as a local drug delivery system in the treatment of chronic periodontitis. Methods: A total of 20 chronic periodontitis patients participated as per the set inclusion and exclusion criteria. Complete scaling and root planing (SRP) was done for all subjects and pluronic F-127 gel containing green tea catechin was applied on one site. The contralateral site received SRP alone. The plaque index (PI), gingival index (GI), and probing pocket depth (PPD) were recorded at baseline and on the 28th day. Results: At the 28th-day follow-up, green tea catechin tooth sites showed significantly lower mean scores (GI = 0.55, p = 0.30 and PPD = 3.35 mm) than the corresponding SRP tooth sites (GI = 1.25, PI = 1.15, and PPD = 4.40 mm) (p < 0.05). Conclusion: When compared to scaling and root planing alone, the local drug delivery gel containing green tea catechin as an adjuvant was more effective in reducing the clinical parameters of periodontitis. Keywords: Adjuvant therapy, Camellia sinensis, Local drug delivery, Periodontal pocket
Microbial Infection of Orthodontic Synthetic Intermaxillary Elastics in Differents Types of Manipulation: An In Vitro Study

Background: Intermaxillary elastic is considered important sources of energy in orthodontic movement. However, the majority of this type of material, mainly those of Brazilian brands, is sold in packets containing 1000 units, which obliges the orthodontist or assistant to manipulate these, in order to separate them into a smaller quantity for each patient. The care taken by the working team is essential for preserving the integrity of the health of both the team and patients. Aim/objectives: the purpose of this study was to perform an in vitro evaluation of synthetic intermaxillary elastics from different manufacturers, to verify the presence of microorganisms at the time of opening the package and its application, by different forms of manipulation. Methods: 120 synthetic intermaxillary elastics were divided into four groups according to different trademarks and type of manipulation. These were incubated at 37 o C and evaluated after time intervals of 24 hours, 48 hours, 72 hours, 4 days, 7 days and 10 days. The cultures were analyzed by visual inspection and when the culture medium presented turbidity, the presence of contamination was considered. Findings/results: Bacterial contamination was only found in the groups that occurred hand manipulation of the materials. Discussion: The elastics tested in this study presented no evidence of microbial contamination before manipulation; manipulation of the elastics with the use of gloves and sterile forceps prevented contamination by microorganisms; the elastic manipulation with hands is not recommended.
A review on the genus Metarhizium as an entomopathogenic microbial biocontrol agent with emphasis on its use and utility in Mexico

ABSTRACT Metarhizium is a genus of entomopathogenic fungi that was initially classified into three species and varieties. More recently, DNA sequencing has improved the phylogenetic resolution of Metarhizium which now includes 30 species. The insect host ranges vary within the genus and some species such as M. robertsii have broad host ranges, while others such as M. acridum show a narrow host range and are restricted to the order Orthoptera. Metarhizium spp. are ubiquitous naturally occurring soil inhabiting fungi, and some are rhizosphere colonisers and their diversity has been attributed to various selective factors (habitat type, climatic conditions, specific associations with plants and insect hosts). Metarhizium have been used for the biological control of insect pests that affect economically important agricultural crops and have been tested under laboratory and field conditions for the control of insect vectors of human disease, showing the effectiveness of the fungus against the target pest. In Mexico, Metarhizium species have been used for the control of insect pests such as the spittlebug (Hemiptera: Cercopidae), and locusts (Orthoptera) that affect crops such as corn, bean and sugarcane. Biosafety studies, such as dermal and intragastric tests in mammalian models have also been carried out to ensure safety to humans and other animals. Metarhizium shows great promise as an alternative to chemical insecticides that has relatively low impact on human health and the environment. Key features of Metarhizium for biocontrol of insects are outlined with special reference to their utility in Mexico.
An Exploration of Diverse Historical Influences on Leading and Managing Continuing Professional Development in Colleges in the Post-Incorporated English Further Education Sector

This thesis explores the development of diverse historical influences on the leadership and management of continuing professional development (CPD), within post-incorporated general further education (FE) colleges in England. It has a central focus on the period of the first two decades after 1993 when colleges had left local authority control on incorporation. Underlying the research questions is a consideration of the educational, professional and business orientations of individual leaders, and the extent to which nuanced influences on CPD leadership co-exist, are balanced or in conflict, within the process of leaders mediating, translating and applying sector CPD policy in colleges. The combination of professional life history reflective data used with that of historical public documentary data aims to offer deeper insights into the range and relationship between the influences involved. The effect and differentiation of influences on CPD leadership and management approaches is considered within diverse college internal and external policy contexts of middle and senior managers, and at departmental and cross-college levels. Leaders’ and managers’ approaches to staff support and development are considered in the light of their own professional experiences, the ongoing changing requirements of external policy and resource boundaries as well as subject, skill and knowledge development and scope for individual staff professional enhancement. The scope of CPD leadership was taken to be as wide as that understood by the leaders and managers. The associated concepts of scope for leadership and management agency, internal organisational and internal and external accountabilities, and effects of staff identities in FE are evaluated. Whilst contributing to knowledge and understanding of this area, there is potential for collaborative sharing of leadership experience of the findings which could lead to more effective sharing of expertise, whilst enhancing organisational staff capacity and staffing strategies. There is potential for further research into leadership of CPD access particularly for the significant body of part-time staff in colleges.