Miracle-dz/UniFAR-FTUs huggingface dataset:
Internet Banking Attitudes in Association with Demographics and Motivations

This paper examines Internet banking attitudes associated with demographics and motivations for Internet banking subscribers to access their online banking sites. To find out the relationships among demographics, motivation, and attitude, I conducted ANOVA and regression analysis using survey data. The results of the paper found that age group and experience were significant demographic variable impacting motivation of economic benefits and users with much experience. Male users had stronger motivation of entertainment and getting better information than female users. Users with longer experience and frequent visitors had positive attitude on financial products. All motivation factors had influences on attitudes on both of financial products and Internet banking. This study suggests the features of Internet banking attitudes and motivations by demographics, from which we can figure out how to motivate Internet banking users for them not only to actively access their online banks rather than visit banks in person but also to have positive attitudes on their banks and Internet banking.
Source identification of network diffusion processes with partial observations

In this paper, we study the problem of identifying the source of network diffusion processes by using the contact networks and sampled infections. The dynamic processes are described by the susceptible-infected (SI) model and a maximum likelihood (ML) estimator is formulated for identification of the source. We propose a two-stage method that first locates a set of suspected source nodes and then identifies the infection source from the candidate source nodes by using Markov random field method. Experiments on regular tree and real-world networks verify the effectiveness of our approach.
elt-1, an embryonically expressed Caenorhabditis elegans gene homologous to the GATA transcription factor family

The short, asymmetrical DNA sequence to which the vertebrate GATA family of transcription factors binds is present in some Caenorhabditis elegans gene regulatory regions: it is required for activation of the vitellogenin genes and is also found just 5' of the TATA boxes of tra-2 and the msp genes. In vertebrates GATA-1 is specific to erythroid lineages, whereas GATA-2 and GATA-3 are present in multiple tissues. In an effort to identify the trans-acting factors that may recognize this sequence element in C. elegans, we used a degenerate oligonucleotide to clone a C. elegans homolog to this gene. We call this gene elt-1 (erythrocytelike transcription factor). It is single copy and specifies a 1.75-kb mRNA that is present predominantly, if not exclusively, in embryos. The region of elt-1 encoding two zinc fingers is remarkably similar to the DNA-binding domain of the vertebrate GATA-binding proteins. However, outside of the DNA-binding domains the amino acid sequences are quite divergent. Nevertheless, introns are located at identical or nearly identical positions in elt-1 and the mouse GATA-1 gene. In addition, elt-1 mRNA is trans-spliced to the 22-base untranslated leader, SL1. The DNA upstream of the elt-1 TATA box contains eight copies of the GATA recognition sequence within the first 300 bp, suggesting that elt-1 may be autogenously regulated. Our results suggest that the specialized role of GATA-1 in erythroid gene expression was derived after separation of the nematodes and the line that led to the vertebrates, since C. elegans lacks an erythroid lineage.
20S proteasome, hsp90, p97 fusion protein, PA28 activator copurifying oligomers and ATPase activities

Whether hsp90 acts in an ATP‐depeadent or independent way is of crucial importance for understanding the molecular mechanism of this chaperone and, to day, the involvement of ATP hydrolysis in hsp90 function is still a contreversial subject. ATPase activities may be detected in partially purified hsp90′s preparations from rabbit muscle. We demonstrate that the major contaminant associated with hsp90 is the p97 fusion protein and that these oligomeric structures are copurifying together with the 20S proteasome and its PA28 activator. Improving the purification procedure permits to separate hsp90 and p97 to homogeneity. Then, our attempts failed to detect any significant ATPase activity in the hsp90 fraction. Thus, p97 would be principally responsible for the ATPase activity detected in partially purified hsp90 preparations from rabbit muscle.
Blockade of central orexin 2 receptors reduces arterial pressure in spontaneously hypertensive rats

• What is the central question of this study? Central orexinergic activity is involved in tonic and phasic control of cardiovascular homeostasis. A potential role for elevated central orexinergic activity in the maintenance of hypertension in spontaneously hypertensive rats (SHRs) has not previously been explored. • What is the main finding and what is its importance? We show that central or intra‐rostral ventrolateral medulla blockade of orexin 2 receptors produces a significant reduction of arterial pressure in SHRs, but not Wistar–Kyoto rats. This study demonstrates a previously unrecognized role of orexin 2 receptors in maintaining hypertension in SHRs.
Gliadain, a gibberellin‐inducible cysteine proteinase occurring in germinating seeds of wheat, Triticum aestivum L., specifically digests gliadin and is regulated by intrinsic cystatins

We cloned a new cysteine proteinase of wheat seed origin, which hydrolyzed the storage protein gliadin almost specifically, and was named gliadain. Gliadain mRNA was expressed 1 day after the start of seed imbibition, and showed a gradual increase thereafter. Gliadain expression was suppressed when uniconazol, a gibberellin synthesis inhibitor, was added to germinating seeds. Histochemical detection with anti‐gliadain serum indicated that gliadain was present in the aleurone layer and also that its expression intensity increased in sites nearer the embryo. The enzymological characteristics of gliadain were investigated using recombinant glutathione S‐transferase (GST)–progliadain fusion protein produced in Escherichia coli. The GST–progliadain almost specifically digested gliadin into low molecular mass peptides. These results indicate that gliadain is produced via gibberellin‐mediated gene activation in aleurone cells and secreted into the endosperm to digest its storage proteins. Enzymologically, the GST–progliadain hydrolyzed benzyloxycarbonyl‐Phe‐Arg‐7‐amino‐4‐methylcoumarin (Z‐Phe‐Arg‐NH2‐Mec) at Km = 9.5 µm, which is equivalent to the Km value for hydrolysis of this substrate by cathepsin L. Hydrolysis was inhibited by two wheat cystatins, WC1 and WC4, with IC50 values of 1.7 × 10−8 and 5.0 × 10−8 m, respectively. These values are comparable with those found for GST–progliadain inhibition by E‐64 and egg‐white cystatin, and are consistent with the possibility that, in germinating wheat seeds, gliadain is under the control of intrinsic cystatins.
Investment opportunities and stock liquidity : evidence from DJIM index additions in the Persian Gulf states

This paper investigates the impacts of index additions on the return and liquidity of Shariah-compliant shares in Kuwait, Oman, Qatar, and UAE. The author uses the sample of companies added to the Dow Jones Islamic Market index over the period of January 2008-December 2009. The findings show that stock prices respond positively to index addition events. However, evidence in support of the changes in the liquidity of added shares is mixed, depending on the country and the liquidity measures. These findings have important implications for Shariah-complaint investors, showing that companies whose activities reflect the beliefs and ethos of their investors in the Middle East may also be attractive from an investment point of view.
Manipulating the graphical representation of query results in geographic information systems

An investigation into how the properties of spatial data, in particular their graphical representation, influence the interaction between user and system is presented. Of particular interest are the concepts humans have about spatial data and the operations that allow them to manipulate and examine the graphical representation of spatial data. An overview of the architecture of spatial information systems is given, concentrating on user interfaces for spatial data handling. An investigation into how users manipulate the representation of spatial data is given, followed by the introduction of the corresponding operations necessary to examine the representation. A series of interface snapshots is given to demonstrate these ideas in a simulated user interface. <<ETX>>
Liquisolid Compacts: An Approach to Enhance the Dissolution Rate of Nimesulide

The present study enlightens to enhance the dissolution rate, absorption efficiency and bioavailability of Nimesulide, a poorly soluble-highly permeable drug by preparing liquisolid compacts. Nimesulide liquisolid tablets were prepared by using polyethylene glycol-400 as a non-volatile liquid vehicle, microcrystalline cellulose, hydroxypropyl methylcellulose-E15, starch were used as carrier materials and silica gel as coating material in different ratios. They were characterized for different physical parameters to comply with pharmacopoeial limits. In vitro dissolution profiles of the liquisolid formulations were studied and compared with conventional formulation in pH 7.4 phosphate buffer and it was found that liquisolid tablets formulated with microcrystalline cellulose showed significant higher drug release rates than conventional tablets due to increase in wetting properties. DSC study showed that there is no interaction between the drug and excipients. In conclusion, development of nimesulide liquisolid tablets is a good approach to enhance the dissolution rate.
A Study on Corporate Social Responsibility in Singareni Colleries Company Limited

Corporate Social Responsibility (CSR) is becoming an increasingly important activity to businesses nationally and internationally. It has been on the agenda in India for a considerable period. Most big Indian corporations are engaged in some CSR activities. As is the case in many countries, the private sector is generally more active in this area than the governmental/public sector. The concept of corporate social responsibility in organizations has moral, ethical, and philanthropic responsibilities in addition to their responsibilities. This paper attempts at address the aspects of social responsibility of the business in light of labor welfare at Singareni Collieries Company Limited, Kothagudem, Khamam District in Andhra Pradesh. The objective of this study mainly aims to find out, how the corporate social responsibility practices are held effectively in providing a quality of life to local community people and its role in the development of society. The research is conducted by implementing a structured Questionnaire which was distributed to employees and local community people. It was found that SCCL is undertaking many corporate social responsibilities like conducting awareness programmes, medical camps and community development programmes.
Assessment of Thrombin Inhibitor Efficacy in a Novel Rabbit Model of Simultaneous Arterial and Venous Thrombosis

Summary The importance of thrombin in arterial and venous thrombosis renders thrombin inhibition an important therapeutic target. Identification of novel inhibitors requires an appropriate animal model. We modified a previously reported rat arterial thrombosis model to allow simultaneous assessment of the arterial and venous antithrombotic efficacies of heparin, hirudin, hirulog, a novel thrombin inhibitor H-(N-Me-D-Phe)-Pro-L-trans-4-aminocyclohexyl-Gly-[CO-CO]-NHCH3 (L-370,518) and the factor Xa inhibitor tick anticoagulant peptide in rabbits. Thrombosis was induced through application of 70% ferric chloride to the femoral artery and jugular vein. Incidence of occlusion, thrombus weight, aPTT and plasma inhibitor concentrations were determined. Heparin was efficacious in preventing arterial and venous occlusive thrombosis but at a dose that profoundly elevated aPTT. On a molar dosing basis, the approximate order of potency of the thrombin and factor Xa inhibitors was similar in artery and vein: hirudin>tick anticoagulant peptide>hirulog≥L-370,518. Data suggested that compounds tended to be more potent in preventing venous thrombosis than arterial. This thrombin-dependent model is an economical and efficient approach to arterial and venous antithrombotic efficacy screening that eliminates variabilities encountered when multiple model/multiple animal strategies are employed.
Evaluation of the Interactions Between Multiwalled Carbon Nanotubes and Caco-2 Cells

The aim of this study was to determine whether multiwalled carbon nanotubes (MWNCT) are taken up by and are toxic to human intestinal enterocytes using the Caco-2 cell model. Caco-2 cells were exposed to 50 μg/ml MWCNT (oxidized or pristine) for 24 h, and experiments were repeated in the presence of 2.5 mg/L natural organic matter. Cells displayed many of the properties that characterize enterocytes, such as apical microvilli, basolateral basement membrane, and glycogen. The cell monolayers also displayed tight junctions and electrical resistance. Exposure to pristine and oxidized MWCNT, with or without natural organic matter, did not markedly affect viability, which was assessed by measuring activity of released lactate dehydrogenase (LDH) and staining with propidium iodide. Ultrastructural analysis revealed some damage to microvilli colocalized with the MWCNT; however, neither type of MWCNT was taken up by Caco-2 cells. In contrast, pristine and oxidized MWCNT were taken up by the macrophage RAW 264.7 line. Our study suggests that intestinal enterocytes cells do not take up MWCNT.
Hemoglobin , haptoglobin and hemopexin play a role in HDL inflammatory properties 1 Hemoglobin and its scavenger protein haptoglobin associate with apoA-1 containing particles and influence the inflammatory properties and function of high density lipoprotein

Hemoglobin (Hb) uniquely associates with proinflammatory HDL in atherogenic mice and coronary heart disease (CHD) patients. In this paper, we report that Hb and its scavenger proteins, haptoglobin (Hp) and hemopexin (Hx) are significantly increased in apoA-1 containing particles of HDL both in mouse models of hyperlipidemia as well as CHD patients, when compared to wild type mice and healthy donors, respectively. We further demonstrate that the association of Hb, Hp, and Hx proteins with HDL positively correlates with inflammatory properties of HDL and systemic inflammation in CHD patients. Interestingly, HDL from Hp -/-
ICT Opportunities Unlimited: The International Dimension in Opportunity Development

In the last two decades, research on international entrepreneurship focused on recently founded firms and their international activities (e.g., Zahra and George, 2002). A wealth of evidence presented in the literature suggests that the majority of startups or international new ventures have no choice but to operate across borders from day one (e.g., Oviatt and McDougall, 1994) to pursue their opportunities. A major theme in international entrepreneurship according to Dimitratos and Jones (2005) is international opportunity perception. Yet, to date, few scholars looked beyond the process of inception (Madsen and Servais, 1997; Wakkee, 2004; Kirwan, Van der Sijde, and Groen, 2007) and examined the process opportunity development underlying these (global) ventures. Our contribution will look into the process by which an opportunity scenario unfolds in the context of global startups. We will link theoretical insights on opportunity recognition (see, e.g., Bhave, 1994; Ardichvili, Cardozo, and Ray, 2003; Schwartz and Teach, 2000; Sigrist, 1999) to theoretical insights on international entrepreneurship (Oviatt and McDougall, 2005) and of ICTsupported communication. We will utilize insights ABSTRACT
Demonstration of Entanglement of Electrostatically Coupled Singlet-Triplet Qubits

Entangling Qubits The basic building block of a quantum computer, a qubit, has been realized in many physical settings, each of which has its advantages and drawbacks. Solid-state spin qubits interact weakly with their environment and each other, leading not only to long coherence times but also to difficulties in performing multiqubit operations. Shulman et al. (p. 202) used a double quantum dot to produce a singlet-triplet qubit, where the two quantum states available are a singlet and a triplet formed by two spin-1/2 electrons. Two such qubits are then entangled by electrical gating, which affects the charge configuration of one qubit and that, in turn, influences the electric field experienced by the other. This type of two-qubit entanglement is essential for further development of quantum computing in these systems. The states of two qubits residing in a pair of double quantum dots are rendered interdependent through electrical gating. Quantum computers have the potential to solve certain problems faster than classical computers. To exploit their power, it is necessary to perform interqubit operations and generate entangled states. Spin qubits are a promising candidate for implementing a quantum processor because of their potential for scalability and miniaturization. However, their weak interactions with the environment, which lead to their long coherence times, make interqubit operations challenging. We performed a controlled two-qubit operation between singlet-triplet qubits using a dynamically decoupled sequence that maintains the two-qubit coupling while decoupling each qubit from its fluctuating environment. Using state tomography, we measured the full density matrix of the system and determined the concurrence and the fidelity of the generated state, providing proof of entanglement.
The impact of modern noninvasive cardiac imaging on coronary intervention rates.

OBJECTIVES It remains still unclear whether the use of modern noninvasive diagnostic modalities for evaluation of coronary artery disease (computed tomography coronary angiography (CTCA), nuclear myocardial perfusion imaging (MPI)) were able to change the "diagnostic yield" of invasive coronary angiography (ICA). METHODS The total number of ICA in the years 2000-2009 was related to the number of percutaneous interventions (PCIs) and we assessed whether there was a significant trend over time using time series analyses. We compared these data with the number of patients undergoing CTCA and nuclear MPI in the same time period. RESULTS During the 10-year observational period, 23,397 ICA were performed. The proportion of purely diagnostic ICA (without PCI) remained stable over the whole study period (tau = -0.111, P = 0.721). A CTCA program was initiated in 2005 and 1,407 examinations were performed until 2009. Similarly, the number of nuclear MPI increased from 2,284 in the years 2000-2004 to 5,260 in the years 2005-2009 (P = 0.009). CONCLUSION Despite increasing availability, noninvasive testing modalities did not significantly alter the rate of purely diagnostic ICA, and still are underused as gatekeeper to ICA. Further effort is needed to optimize the use of noninvasive imaging modalities in the work-up process for coronary artery disease.
A 2-population classifier system

This study proposes a 2-population classifier system to increase the computing efficiency of classifier system. The system is applied to solve the Wisconsin Breast Cancer (WBC) problem. The system is compared to the traditional learning classifier system (LCS) and Wilson's extend classifier system (XCS) in terms of computing efficiency and prediction accuracy. On the WBC problem, the average execution time for 2-population classifier system is roughly 19.45% of XCS. Meanwhile, the 2-population classifier system is higher than LCS even to XCS according to the accuracy rate comparisons. Thus, this study presents the 2-population classifier system to achieve both higher prediction accuracy ability and lower execution time.
Analysis of the Presence of Romanian Listed Companies in Tax Havens

In recent years, offshore companies and tax havens have been in the center of many financial scandals, both nationally and internationally. Also, the press reports daily such cases involving numerous companies and businessmen, but also politicians, athletes, actors and other celebrities. If we appeal to a famous statement of Leona Helmesey, which argued that “only the little people pay taxes” (The Economist, 2001), we can say that tax havens are only for the powerful people. Undoubtedly, the subject of offshore economy is perhaps now, more than ever, the focus of attention of both the public and the authorities. A possible explanation can be given by "the sheer size of the phenomenon" and by the fact that one third of foreign direct investments of multinational companies are turning to tax havens jurisdictions (Palan, 2009).
Expression of p16 in post‐radiotherapy cervical biopsies

2009; 9; 433. 3. Brunstein HJ, Lieberman G, Slamon DJ, Winer EP, Klein P. Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy. Ann. Oncol. 2005; 16; 1772–1777. 4. Köbel M, Kalloger SE, Santos JL et al. Tumor type and substage predict survival in stage I and II ovarian carcinoma: insights and implications. Gynecol. Oncol. 2010; 116; 50–56.
Chemical Compositions and Biological Activities of Amomum subulatum Essential Oils from Nepal

The essential oils from the seed and rind of Amomum subulatum Roxb. (collected from Nepal) were obtained by hydrodistillation and analyzed by GC-MS. A total of 87 components were identified among the two essential oils accounting for 99.1%, and 99.0% of the oils, respectively. The two essential oils were dominated by the monoterpenoids 1,8-cineole (60.8% and 39.0%), α-pinene (6.4% and 4.8%), β-pinene (8.3% and 17.7%), and α-terpineol (9.8% and 12.3%). Allelopathic testing of the seed essential oil showed an inhibition of seed germination of Lactuca sativa and Lolium perenne, with IC50 values of 1583 and 1674 μg/mL, respectively. The seed essential oil demonstrated a stronger seedling growth inhibition of L. perenne than of L. sativa. A. subulatum seed and rind oils also showed moderate brine shrimp lethality (LC50 = 28.1 ± 3.0 and 15.0 ± 9.0 μg/mL, respectively). The seed and rind oils were only marginally cytotoxic (20% and 30%% kill on MCF-7 cells at 100 μg/mL, respectively), and antibacterial (MIC ≥ 313 μg/mL), but A subulatum rind oil was appreciably active against the fungus Aspergillus niger (MIC = 19.5 μg/mL). The essential oils of A. subulatum were also screened for nematocidal activity against Caenorhabditis elegans and insecticidal activity against the fruit fly (Drosophila melanogaster) and the red imported fire ant (Solenopsis invicta × richteri). The seed oil was only marginally toxic to the fire ant (LC50 = 1500 μg/mL), but moderately toxic to the nematode and the fruit fly (LC50 = 341 and 441 μg/mL, respectively).
Stiction-driven sealing of surface micromachined channels

In this paper we report on a new technique for the fabrication of hermetically sealed microchannels. The technique exploits the stiction phenomenon to achieve the sealing of surface micromachined channels. Using this technique we fabricated a microchannel device that can self-close after the drying step that follows the sacrificial etch. Our fabrication method avoids the use of auxiliary access holes or apertures and requires no additional sealing steps. The fabricated self-sealing microchannel devices were showed a leak-rate equal or lower than 3.4·10-4 mbar·L/s.