Miracle-dz/UniFAR-FTUs huggingface dataset:
Étude de l'ablation de la limitante interne dans la chirurgie des trous maculaires idiopathiques de stade 3 et 4

Objectif : Evaluer l'interet de l'ablation de la limitante interne (LI) dans la chirurgie des trous maculaires (TM) idiopathique. Materiel et methodes : Analyse retrospective comparative des resultats de la chirurgie du TM de stade 3 et 4, comparant 2 protocoles chirurgicaux effectues par un meme chirurgien : technique chirurgicale classique avec administration de plasma autologue et gaz expansif dans les deux groupes, ablation systematique de la LI coloree prealablement par le vert d'indocyanine (infracyanine®) pour les derniers patients dans le 2 e groupe. Resultats: Trente-neuf yeux de 36 patients presentant un TM evoluant depuis en moyenne 9 mois ont ete operes, 21 yeux (53,8 %) ont beneficie de l'ablation de la LI. Le taux de succes anatomique apres une intervention etait significativement plus eleve dans le groupe ayant beneficie d'un pelage de la LI que dans le groupe sans pelage de la LI (90 % et 50 % respectivement, p < 0,01); le taux de succes anatomique atteignait 61 % apres 2 interventions dans le dernier groupe. On observait une disparition complete du TM en angiographie et a l'OCT dans 90 % des succes anatomiques du groupe avec pelage de la LI et dans seulement 22 % dans l'autre groupe. On notait un gain d'acuite visuelle superieur ou egal a deux lignes pour 62 % des yeux operes avec pelage de la LI et pour 44 % des yeux de l'autre groupe. Il existait une difference statistiquement significative entre les deux groupes concernant le gain de seuil maculaire (p < 0,001). Conclusion: Cette etude suggere que l'ablation de la LI semble avoir un effet favorable sur la recuperation anatomique et fonctionnelle dans la chirurgie des TM. Le mecanisme d'action en reste discute. Ces resultats doivent etre confirmes par des etudes prospectives randomisees.
Phase I trial of oral vorinostat in combination with bexarotene in patients with advanced cutaneous T-cell lymphoma

8613 Background: The histone deacetylase (HDAC) inhibitor vorinostat and the RXR-selective retinoid bexarotene are each clinically active and safe as monotherapy in the treatment of cutaneous T-cell lymphoma (CTCL). This study was performed to test whether the combination of vorinostat and bexarotene could be safely administered. Methods: A Phase I trial of vorinostat (200, 300, or 400 mg daily) in combination with bexarotene (150, 225, or 300 mg/m2 or 150 mg, daily) was conducted. Cycles were repeated every 28 d for ≤6 cycles until PD or intolerable toxicity. Adult patients (pts) with stage ≥IB progressive, persistent, or recurrent CTCL refractory to ≥1 systemic therapy were eligible. Pts must not have received prior bexarotene within 3 m or prior HDAC inhibitor treatment and must have adequate hematologic, hepatic, and renal function. The primary objective was to determine the maximum tolerated dose (MTD). Activity and safety of the combination regimen were also assessed. Results: 19 pts have been enrol.
Modulation of the impacts of Madden–Julian Oscillation on winter rainfall in China by El Niño‐Southern Oscillation

This study revealed the modulation of the impacts of Madden–Julian Oscillation (MJO) on winter rainfall in China by El Niño‐Southern Oscillation (ENSO) using reanalysis data and statistical analysis. When MJO is active over the Indian Ocean, its impacts are strengthened by El Niño, leading to enhanced positive rainfall anomalies in eastern China. However, the effects of MJO are counteracted by La Niña; thus, significant positive rainfall anomalies exist only in Zhejiang Province and adjacent areas. MJO activity over the western Pacific induces opposite rainfall anomalies in South China between El Niño and La Niña winters; rainfall in South China increases (decreases) in El Niño (La Niña) winters. Such differences in rainfall anomalies are closely related to anomalous circulation and moisture transport. Anomalous southwesterlies in eastern China are enhanced in El Niño winters when MJO is active over the Indian Ocean, which leads to increased moisture transport towards China and stronger ascending motion in eastern China. But the anomalous southwesterlies are weakened in La Niña winters, thereby resulting in less moisture transport and convergence. When MJO is active over the western Pacific, anomalous northeasterlies in mainland China are enhanced (weakened) in La Niña (El Niño) winters, which strengthens (weakens) the moisture divergence and descending motion in China. Moisture convergence anomalies that explain the rainfall anomalies in ENSO winters are mainly attributed to the effects of low‐frequency background state (LFBS) moisture and meridional winds. It was found that ENSO modulates the impacts of MJO by two main ways. First, ENSO can regulate the intensity and distribution of MJO activity. Therefore, MJO in the same phase will lead to different circulation and moisture transport anomalies in China. Second, ENSO‐induced LFBS circulation and moisture anomalies can also influence the moisture convergence in China, which will strengthen or weaken the effects of MJO.
Evaluation of sustainability concepts in public housing projects in ogun state, nigeria.

The issues associated with housing are colossal and multifaceted, displaying clear and concise differences in various parts of the world. As is the case of most urban environments, the problem of housing can no longer be limited to the quantity of houses available, it should also include the quality and the location of these housing units. As a result, this study intends to assess the different sustainability concepts adopted in the planning, design and construction of public Housing in Ogun State. The objectives of the study were to, evaluate the physical characteristics and conditions of the housing units, examine the socio-economic characteristics of the residents, and determine factors which affect the level of satisfaction of the residents. 274 housing units were assessed, from four public housing estates in the state, between the months of December, 2018 and February, 2019. Data was gathered by administration of questionnaires as well as interviews to household heads. The data was analyzed using descriptive and inferential techniques. The result of study highlighted that the housing estates were assessed to be sustainable as regards the housing density of the units and the affordability levels, however the estates were deemed unsustainable based on type of building materials used, proximity to basic amenities, and non-existence of communal facilities. The study concluded that relevant agencies as regards housing in the state, should focus on the provision and maintenance of public facilities so as to improve resident’s satisfaction and also make use of adaptable spaces when designing houses, so as to cater for unexpected growth in the family and improve quality of life of the occupants.
The Role of Assessment in Counselor Certification

The first national certification began in 1972 with the incorporation of the Commission for Certification of Rehabilitation Counselors. In 1979, the National Academy for Certified Clinical Mental Health Counselors began certifying counselors trained in the specialty of clinical mental health counseling. Soon after, in 1984, the National Vocational Guidance Association (now the National Career Development Association)began certifying career counselors. In 1983, the National Board for Certified Counselors (NBCC) began certification for general practice counselors. And, as this digest is being written, the International Association of Marriage and Family Counselors is beginning a certification process. Clinical mental health counselors and career counselors have merged with the National Board for Certified Counselors to become a specialty certification of the general practice of counseling. Across the realm of certifications in the counseling profession is the common thread of assessing individual counselors, training, supervision, experience, and knowledge; the similarities across the processes are remarkable.
Çocukluk Çağı Kronik Hastalıklarında Tıbbi Beslenme Tedavisi Bağırsak Mikrobiyotasını Etkiler mi?

A healthy gut microbiota benefits the host in many respects, including protection from pathogens and maturation of immune responses. The emerging evidence shows that intestinal microbiota is associated with the development of childhood diseases such as allergic diseases, celiac, type 1 diabetes and obesity. Nutrition is considered to be the main environmental factor affecting the diversity and functionality of the gut microbiota. Diet has been shown to cause significant changes in the intestinal microbiota in a short time. In this respect, it is thought that medical nutritional therapy in childhood chronic diseases will affect the intestinal microbiota composition. Understanding the relationship and interactions between nutritional therapies and intestinal microbiota is critical to disease management. In this review, the effects of medical nutritional therapies on intestinal microbiota in some childhood chronic diseases are examined.
Open-angle glaucoma

Open-angle glaucoma (OAG) is an important cause of irreversible blindness. In OAG, loss of retinal ganglion cells leads to damage of the optic nerve. This causes visual field loss and eventually blindness. Changes in the optic nerve head (ONH) can be examined with confocal scanning laser ophthalmoscopy (Heidelberg Retina Tomograph [HRT]), scanning laser polarimetry (GDx) or Optical Coherence Tomography (OCT). Important risk factors for OAG are elevated intraocular pressure (IOP), high age, myopia, ethnicity, thin central corneal thickness, and a positive family history for OAG. However, the pathophysiology still remains largely unknown. In order to improve the diagnosis and learn more about the pathophysiology of this blinding disease, the main objectives of the research described in this thesis were to: 1) address the diagnostic utility of the OCT scan for OAG, 2) elucidate new risk factors for OAG or IOP, 3) identify novel genetic variants associated with OAG or its endophenotypes, and 4) assess the functional consequences of genetic variants associated with OAG. Our study populations included the population-based Rotterdam Study, the Erasmus Rucphen Family (ERF) Study, population-based studies from the European Eye Epidemiology (E3) Consortium and population-based and OAG case-control studies from the International Glaucoma Genetics Consortium (IGGC).
Size-specific dose estimate can be used to calculate patient-specific blood dose from paediatric CT examinations

Poster: "ECR 2015 / B-0781 / Size-specific dose estimate can be used to calculate patient-specific blood dose from paediatric CT examinations" by: "C. Franck, C. Vandevoorde, P. Smeets, E. Achten, K. L. Verstraete, H. Thierens, K. Bacher; Ghent/BE"
Assessing the Moderating Effect of Corruption on the E-Government and Trust Relationship: An Evidence of an Emerging Economy

The foremost purpose of this article is to investigate the effect of electronic-government (e-government) on public trust and the moderating impact of corruption on this relationship. The data was obtained through a structural questionnaire involving 800 Pakistani citizens at the local level. The true response rate was 58.3%. The data was analyzed using confirmatory factor analysis, multiple regression and stepwise hierarchal regression. The results showed there is an empirically significant association among e-government practices and public trust in local self-government and a negative moderating role of corruption. The findings suggest that e-government can develop a procedure-based trust by advancing connections with people and their insights of responsiveness. The individuals’ viewpoints about the state, including trust, are fundamental concerns for the governance and administrative system. Testing these above associations via a moderation technique is a novel process which contributed to the current study on e-government.
Allergic Subjects Have More Numerous Respiratory Infections and Severe Gastrointestinal Infections Than Non-Allergic Subjects: Preliminary Results

Allergic disorders are characterized by Th2-polarization, thus physiological Th1-dependent mechanisms for fighting infectious diseases (ID) may be defective. This study aims at evaluating the number and duration of respiratory (RI) and gastrointestinal diseases (GI) in allergic and non-allergic subjects in a particular community: the crew of an operative warship consisting of 189 persons (171 males and 18 females). The study period lasted for 5 months during an operative mission. The number and duration (days) of RI and GI were evaluated. Allergic subjects experienced more numerous RI (p=0.0029) and more severe GI (p=0.0001) than non-allergic subjects. This preliminary study provides evidence that allergic subjects may have more numerous RI and prolonged GI than non-allergic subjects.
Study of prevalence pattern of neoplastic intracranial tumor in the tribal area of Rajasthan, India

Background: Prevalence estimates available for brain tumors reflect the portion of tumors that are malignant. Just as routine incidence statistics from cancer registries under represent the full spectrum of primary brain tumor cases. Prevalence rates are ideally suited to provide an overall estimate of cancer survivorship and direction for health planning. Methods: A total of 70 cases of CNS tumors were retrieved from the archives of the Department of Pathology, Geetanjali Medical College & hospital, Udaipur from April 2014 to September 2016. The diagnoses in all the cases were made on histological examination of processed tissue. Results: In our study astrocytoma was the most common brain tumor (34.28%), followed by meningioma (32.85%). The third common tumor was oligodendroglioma (11. 42%). However, metastatic brain tumors were seen in only 5.55 % of cases in the present study. Conclusions: Males were at higher risk of developing CNS lesions in comparison to females. WHO Grade I lesions were more common in our institutional set up. Astrocytoma WHO grade IV lesions were more common in comparison to Grade I lesions, indicating need for imaging and neurology consultation at primary grass root level.
Total Least-Squares Iterative Closest Point Algorithm Based on Lie Algebra

In geodetic surveying, input data from two coordinates are needed to compute rigid transformations. A common solution is a least-squares algorithm based on a Gauss–Markov model, called iterative closest point (ICP). However, the error in the ICP algorithm only exists in target coordinates, and the algorithm does not consider the source model’s error. A total least-squares (TLS) algorithm based on an errors-in-variables (EIV) model is proposed to solve this problem. Previous total least-squares ICP algorithms used a Euler angle parameterization method, which is easily affected by a gimbal lock problem. Lie algebra is more suitable than the Euler angle for interpolation during an iterative optimization process. In this paper, Lie algebra is used to parameterize the rotation matrix, and we re-derive the TLS algorithm based on a GHM (Gauss–Helmert model) using Lie algebra. We present two TLS-ICP models based on Lie algebra. Our method is more robust than previous TLS algorithms, and it suits all kinds of transformation matrices.
MOOC instructor motivation and career development

ABSTRACT As massive open online courses (MOOCs) proliferate, a better understanding of MOOC instructors is essential. This study examined the motivation as well as the career and professional development of 142 MOOC instructors using a mixed-methods approach entailing an online survey combined with six MOOC instructor interviews. The research findings indicated that instructors’ motivation to teach MOOCs primarily related to intrinsic motivation. Importantly, this study classified the motivational factors of MOOC instructors into seven categories. While the frustrations of MOOC instructors included time for creating MOOCs and a lack of interaction in MOOCs caused, in part, by heavy reliance on asynchronous communication, many perceived that MOOC teaching positively influenced their professional development. Most MOOC instructors learned how to teach MOOCs informally and individually. Nevertheless, they tried to help other MOOC instructors. This study points to the strong need for professional development of MOOC instructors in developing and effectively MOOCs.
Advanced Algorithms for Medical Image Processing

Medical image processing in healthcare and biomedical research centers has demonstrated predominant advantages to the world [1]. Lately, a lot of research articles were published, featuring the need for Medical image processing in various health issues of the human body and its major internal organs. The quintessence of diagnostic imaging algorithms is to facilitate the process of observing a patient's body and its major internal organs with higher efficiency and accuracy in recognition diseases or injuries [2]. Normally, diagnostic reports of patients incorporate radiographic representation of human body or its parts; utilization of various medical image processing techniques improves the procedure applied to the patients. Algorithms plays a major role in the artifacts filtering, segmentation, feature extraction and classification, which will expedite the disease diagnosis. In the recent two decades, deep learning algorithms played a vital role in the medical image processing with improved performance than the conventional machine learning algorithms, such advanced algorithms that show greater accuracy in the classification of cancer cells, lesions, organ segmentation and medical image enhancement with an average accuracy ranges of 96% to 98% [3]. In the mere future, advanced computational and learning approaches like Deep learning and hybrid deep learning approaches will play a vital role in the field of diagnostic imaging with most substantial clinical impact on medical imaging examinations to provide improved decision support in medical image interpretation and analysis [4 10].
A COMPARATIVE EVALUATION OF INTRAVENOUS DEXMEDETOMIDINE AND CLONIDINE AS PREMEDIC ATION FOR PROLONGATION OF BUPIVA CAINE SUBARACHNOID BLOCK FOR LOWER LIMB ORTHOPAEDIC SURGERY

BACKGROUND: Addition of α2 adrenergic agonists with local anaesthetics in bupivacaine spinal anaesthesia prolongs the duration of sensory and motor blockade and postoperative analgesia with minimal haemodynamic alterations. AIM AND OBJECTIVES: To compare and evaluate the efficacy of intravenous dexmedetomidine and clonidine as premedication on subarachnoid blockade duration, postoperative analgesia, and sedation score in patients undergoing lower limb orthopaedic surgeries in bupivacaine (0.5%) heavy intrathecal block. MATERIALS AND METHODS: We carried out a prospective, randomized, double blind study in which 60 patients of ASA status I or II, scheduled for orthopaedic lower limb surgery under spinal anaesthesia, were randomly allocated into two groups of 30 each group A and group B. Group A received dexmedetomidine 0.5μg/kg IV and group B received clonidine 1μg/kg in 10 ml of normal saline intravenously as premedication over 10 min., before subarachnoid blockade with 3.0 ml. of 0.5% hyperbaric bupivacaine. Onset time and regression times of both sensory and motor blockade, haemodynamic parameters were recorded. Duration of postoperative analgesia and sedation score with adverse effects were also recorded. RESULTS: The sensory block level was higher (T5-T7) and earlier in onset (1.81±1.75min.) in dexmedetomidine group than clonidine with level (T6-T8) and onset (2.56±1.62min.). Dexmedetomidine also increased the onset (3.54±3.07min.) and duration (265.45±41.50min.) of motor block achieved as compared to clonidine. The Ramsay sedation score was also greater in dexmedetomidine group than clonidine group (P<0.0001). CONCLUSION: Single dose of premedication with intravenous dexmedetomidine is better than intravenous clonidine during bupivacaine spinal anaesthesia in orthopaedic lower limb surgeries for prolongation of sensory and motor blockade.
Extraction of Elastooptic Coefficient of Thin-Film Arsenic Trisulfide Using a Mach–Zehnder Acoustooptic Modulator on Lithium Niobate

An acousto-Optic Modulator (AOM) formed by an Arsenic Trisulfide (As<inline-formula><tex-math notation="LaTeX">$_2$</tex-math></inline-formula>S<inline-formula><tex-math notation="LaTeX">$_3$</tex-math></inline-formula>) Mach–Zehnder interferometer (MZI), operating in a push-pull configuration and placed inside a surface acoustic wave (SAW) cavity on a Y-cut Lithium Niobate (LN) wafer is demonstrated. This is the first demonstration of such acousto-optic (AO) modulator in this As<inline-formula><tex-math notation="LaTeX">$_2$</tex-math></inline-formula>S<inline-formula><tex-math notation="LaTeX">$_3$</tex-math></inline-formula>-LN hybrid platform. In this approach, the high index contrast of As<inline-formula><tex-math notation="LaTeX">$_2$</tex-math></inline-formula>S<inline-formula><tex-math notation="LaTeX">$_3$</tex-math></inline-formula> waveguides is exploited to attain a high optical confinement. Additionally, the placement of the photonic MZI inside the SAW cavity enhances the AO interaction due to the high quality factor (Q) of the SAW resonator. An analytical expression that describes such enhancement as a function of the elasto-optic (EO) coefficient of As<inline-formula><tex-math notation="LaTeX">$_2$</tex-math></inline-formula>S<inline-formula><tex-math notation="LaTeX">$_3$</tex-math></inline-formula> is derived in conjunction with COMSOL finite element methods to describe strain in the SAW cavity. By fitting this expression to experimental data, the EO coefficient (<inline-formula><tex-math notation="LaTeX">$p_{11}$</tex-math></inline-formula> and <inline-formula><tex-math notation="LaTeX">$p_{12}$</tex-math></inline-formula>, where <inline-formula><tex-math notation="LaTeX">$p_{11} \approx p_{12}$</tex-math></inline-formula>) for As<inline-formula><tex-math notation="LaTeX">$_2$</tex-math></inline-formula>S<inline-formula><tex-math notation="LaTeX">$_3$</tex-math></inline-formula> is extracted to be 0.29 at the wavelength of 1550 nm. This is the first time that the EO coefficient of thin film As<inline-formula><tex-math notation="LaTeX">$_2$</tex-math></inline-formula>S<inline-formula><tex-math notation="LaTeX">$_3$</tex-math></inline-formula> is experimentally derived.
Sistema de comunicación, poder y socialismo: el caso de Cuba

Las ciencias sociales han acunado conceptos y teorias elaborados con frecuencia desde una perspectiva critica, que dan cuenta de las estrechas relaciones anudadas en las sociedades contemporaneas entre el poder y los medios de comunicacion. Sin embargo, son menos frecuentes los estudios de esas relaciones en el seno de los paises socialistas que, como cualquier otra sociedad, cuentan con colectivos que ostentan el poder politico y economico, y ejercen como elites simbolicas. La diferencia a menudo radica en la forma en que estos paises justifican el uso de los medios de comunicacion, con estrictos fines ideologicos, atribuyendose la orientacion de su sistema comunicacional a la “vanguardia de la clase trabajadora”, esto es, al partido comunista. Este estudio examina el caso cubano a partir de la descripcion de su estructura comunicativa y del analisis del discurso normativo que la sustenta, desde 1959 hasta 2018. Adoptando un enfoque metodologico estructural y desde el paradigma de investigacion que propone el analisis critico del discurso, se constata que las elites simbolicas que controlan el discurso publico en Cuba han instituido un mecanismo de legitimacion eficaz durante casi seis decadas, apoyado en una organizacion mediatica acorde con sus intereses, y en el desarrollo de un marco regulatorio que condiciona el acceso y el contenido de los medios al reconocimiento de su ideologia. Se observa que sus formas de produccion comunicativa conviven y dialogan con un modelo de comunicacion publica donde prima una logica de rentabilidad sociocultural que marca una diferencia notable con otros sistemas comunicativos.