Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental Research of the Impacts of Qilian Shupi Formula on Gastric Mucosal Blood flows and Pathological Morphology for CAG Rats

Objective To observe the impacts of qilian shupi formula on the gastric mucosal pathological morphology,blood flow and thickness for the rats with chronic atrophic gastritis(CAG)and precancerous lesions by the randomized and controlled animal experiment.Methods 120 rats were randomized into groups according to the body weight.20 rats were divided into a normal group.For the rest rats,the complex modeling method,"MNNG+ranitidine+ethanol+appetite maladjustment"was adopted to duplicate Wistar rat models of CAG precancerous lesion.Determined by the random sampling pathological detection,the rats of successful modeling were randomized into a model group,a weifuchun group and the large-dose,middle-dose and small-dose qilian shupi formula groups,15 cases in each one.After corresponding medicinal intervention,the gastric mucosal pathological change was observed and the gastric mucosal blood flow and thickness were detected.Results Qilian shupi formula reduced the incidence of CAG precancerous lesion for the rats,increased the gastric mucosal blood flow and thickness for the rats with CAG precancerous lesion.Conclusion Qilian shupi formula is the effective compound for the treatment of CAG precancerous lesion and it can apparently increase gastric mucosal blood flow and thickness for CAG rats,which is probably one of the mechanisms on the effect.
Examining the Evidence Base for Occupational Therapy with Clients following Stroke

In order to conduct occupational therapy services that are evidence based, studies are urgently required which demonstrate the effectiveness of interventions offered. This paper presents the findings of a study undertaken to determine occupational therapy outcomes for clients with stroke during inpatient rehabilitation. The participants were 43 clients with stroke and four occupational therapists. Therapy outcomes for personal activities of daily living were measured using the Functional Independence Measure (Adult FIMSM); instrumental activities of daily living were measured using the Assessment of Living Skills and Resources (ALSAR); and quality of life was measured using the Quality of Life Index (Q-L Index) and a semi-structured interview. The semi-structured interview was also used to understand clients' perceptions of the outcome of their participation in occupational therapy. The data were collected at client admission, discharge and 3 months' follow-up. The results indicated that the clients believed that their ability to perform activities of daily living (Adult FIMSM t (38) = −7.80, p = 0.000, and ALSAR t (35) = 4.82, p = 0.000) and their quality of life (Q-L Index t (39) = −7.23, p = 0.000) improved over the course of their inpatient rehabilitation. The therapists also rated the clients as improving during their rehabilitation in relation to activities of daily living (Adult FIMSM t (42) = −9.71, p = 0.000, and ALSAR t (40) = 7.75, p = 0.000) and quality of life (Q-L Index t (39) = −11.20, p = 0.000). Many of the clients interviewed attributed these gains to participation in the occupational therapy programme. In conclusion, this study demonstrated that a triangulated approach to data collection and analysis was useful in providing evidence that occupational therapy, as part of comprehensive rehabilitation, made a difference to the lives of many of the clients studied.
Hemorrhagic colitis associated with a rare Escherichia coli serotype

We investigated two outbreaks of an unusual gastrointestinal illness that affected at least 47 people in Oregon and Michigan in February through March and May through June 1982. The illness was characterized by severe crampy abdominal pain, initially watery diarrhea followed by grossly bloody diarrhea, and little or no fever. It was associated with eating at restaurants belonging to the same fast-food restaurant chain in Oregon (P less than 0.005) and Michigan (P = 0.0005) and with eating any of three sandwiches containing three ingredients in common (beef patty, rehydrated onions, and pickles). Stool cultures did not yield previously recognized pathogens. However, a rare Escherichia coli serotype, O157:H7, that was not invasive or toxigenic by standard tests was isolated from 9 of 12 stools collected within four days of onset of illness in both outbreaks combined, and from a beef patty from a suspected lot of meat in Michigan. The only known previous isolation of this serotype was from a sporadic case of hemorrhagic colitis in 1975. This report describes a clinically distinctive gastrointestinal illness associated with E. coli O157:H7, apparently transmitted by undercooked meat.
Ca2+ Signalling in Damaged Endothelium: Do Connexin Hemichannels Aid in Filling the Gap?

A monolayer of endothelial cells (ECs) lines the lumen of blood vessels and forms a multifunctional trans- ducing organ that regulates cardiovascular homeostasis. Disruption of endothelial integrity, as a result of either angioplasty or stent deployment, may produce a late in-stent restenosis and limit the beneficial outcome of reconstructive vascular surgery. Restoration of endothelial lining requires spreading, migration and proliferation of ECs nearby the lesion site. Intracellular Ca 2+ signalling plays a major regulatory role in stimulating wound healing, however, the mechanism whereby injury increases Ca 2+ levels at the wound edge is still unclear. The analysis of Ca 2+ signals elicited by scraping an endothelial monolayer in vitro suggested the involvement of intracellular Ca 2+ release from InsP3-sensitive stores and Ca 2+ entry through unknown ion channels in the plasma membrane. Recent studies carried out by our group on excised rat aorta highlighted a novel role for connexin hemichannels (ChHcs) in mediating Ca 2+ entry in injured endothelium. This observation sheds new light on the notion that the rate of wound repair is reduced in ECs transfected with dominant negative connexin inhibitors. Understanding the signal transduction pathway leading to EC activation is likely to provide novel targets to design therapeutic applications aiming at restoring endothelial integrity and treating cardiovascular diseases.
Ethnic Differences in Inflammatory Bowel Diseases

have investigated all first and second degree immigrants from our IBD patient cohort. In Antwerp – Belgium there is an important Moroccan immigrant population since the 1960s. Phenotype differences were assessed between Moroccan and Caucasian immigrants. We looked at age at diagnosis, sex, disease location and behavior (Montreal classification), extraintestinal manifestations, need for anti-TNFα treatment and surgery. Our single-center results suggest that first and second degree Moroccan immigrants with IBD suffer predominantly from Crohn’s disease with a more severe phenotype characterized by penetrating disease leading to higher rates of CD-related surgery and need for anti-TNFα treatment. In addition, extraintestinal manifestations tend to be more prevalent in the Moroccan immigrant population. Possible explanations are discussed.
A study on the detection of double faults

Fault-based testing aims at selecting test cases to detect hypothesized faults in a program. Ideally, such selected test cases can guarantee to detect hypothesized faults if they do appear in the programs. Most fault-based testing strategies derive their test cases based on the assumption that at most one of the hypothesized faults is committed by the programmer. However, empirical studies show that multiple faults occur more often in programs and test case selection strategies developed for single faults cannot guarantee to detect multiple faults. In this thesis, double faults that might have occurred within Boolean expressions are studied. A double fault is defined as the occurrences of any two single faults. Since the different order of occurrences of two single faults in a double fault may result in different faulty expressions, double faults were classified into two categories, namely double fault with and without ordering. After modelling faulty expressions from these two categories, we compared these faulty expressions and enumerate all possible faulty expressions of double fault in Boolean expressions. The detection conditions of the considered faulty expression were studied from a theoretical perspective and are characterized based on certain properties of test cases. These conditions helped to identify and develop test case selection strategies to detect such double faults. After examining the fault detection capability of some existing test case selection strategies developed for single faults, six test case selection strategies were proposed to supplement an existing test case selection strategy to detect double faults. We proved that these strategies are guaranteed to detect double faults and investigate the cost of these strategies for double faults detection. This thesis helps us to better understand how different faults occur in a Boolean expression and how they interact with each other. This provides further insight for modelling and detecting multiple faults such as triple faults.
Coronary Anomalies :Understanding of Normal Coronary Artery Development for Insight in Treatment of Coronary Artery Disease

Coronary artery anomalies (CAA)are rare congenital abnormalities with incidence of about 1% in the general population. 2 Unfortunately, despite the low incidence, CAA can cause sudden cardiac death. Identifying the course of the artery is critical for appropriate management. We present a rare case of the left coronary artery arising from the right coronary ostium with special emphasis on normal coronary artery development as possible insight for treatment of dis eased heart.
Forestry structure of populations of Pseudotsuga menziesii (Mirb.) Franco in the states of Tlaxcala and Puebla

Pseudotsuga menziesii populations in central Mexico are small, fragmented and affected by natural and anthropogenic factors. Little is known about the stand structure of these populations, which limits development of management programs despite the protected status of the species. The objective of this study was to characterize and to compare the stand structure of Pseudotsuga forest in seven locations in the states of Tlaxcala and Puebla. A systematic sampling with circular nestled plots of 0.1, 0.05 y 0.005 ha were used to register stand attributes including diameter at breast height (DBH) of alive, death and stumps of all tree species. Results in basal area and Value of Importance Index showed that all locations are dominated by an association of Pseudotsuga-Quercus sp. , and to a less extent by other conifer species. Diameter distribution of Pseudotsuga are non-regular and unbalanced, lacking small ( 85 cm) diameter classes. Stands in Tlaxcala showed higher densities of standing death trees and stumps than those of Puebla. A modified Morista’s Index of Similitude suggested the influence of geographic proximity of populations as well as the disturb factors, in shaping observed diameter distributions.
Biological effects of co-transfection of TGFβ_1 and VEGF mediated by AAVon promoting healing of the cutaneous ulcer in diabetes mellitus

Objective To observe the biological effects of adeno-associated virus(AAV) mediated transforming growth factor β1(AAV-TGFβ1) and vascular endothelial growth factor(AAV-VEGF) on promoting the healing of cutaneous ulcer in diabetic rabbits.Methods The dermal ulcer models of diabetic rabbits were established by injecting alloxan(130mg/kg) via ear vein,and the ulcer wound was made.In the co-transfection group,the wound was locally infiltrated,and injected with AAV-TGFβ1 virus and AAV-VEGF virus.The rabbits in the control group were treated with injection of saline.The levels of TGFβ1 and VEGF gene transcription in the healing tissue were detected with polymerase chain reaction(PCR) 1 month postoperatively.The capillary density in the wound margin was counted with microcirculation microscope 3 weeks postoperatively.The collagen I and III were isolated and detected with western blotting.The content of collagen in the ulcer healing tissue was detected 1 day and 1,2,3 weeks,1,2,3,4,5 and 6 months postoperatively.The thickness,color and quality of the wound healing were observed postoperatively.Results All the 24 rabbits were involved in the analysis of results:(1) The expressions of TGFβ1 and VEGF gene transcription in the co-transfection group were increased as compared with those in the control group. (2) The capillary density at the wound margin in the co-transfection group was higher than that in the control group[(19.18±3.56),(6.43±1.52)/mm2,t=3.21,P0.05]. (3) The content of collagen I in the ulcer healing tissue in the co-transfection group was obviously increased,and the proportion of collagen I in the constituent ratio of collagen I and III was increased.The contents of collagen in the ulcer healing tissue at 1 day after transfection were close without significant difference between the two groups(t=1.55,P0.05). After that,the contents of collagen in the co-transfection group were all significantly higher than those in the control group(P0.05). Conclusion The combination of AAV-TGFβ1 and AAV-VEGF can efficiently transfect the dermal ulcer wound in diabetic rabbits,and obviously ameliorate the condition of ulcer healing.
Besökarundersökning i Ekenäs skärgårds nationalpark 2012

The Ekenäs Archipelago National Park was founded in 1989 and is managed by Metsähallitus Natural Heritage Service. Visitor surveys are done in the national parks on a regular basis according to Metsähallitus’ directives. The previous survey in Ekenäs, which was done in 2007 functions as a basis of comparison for this survey. Visitor surveys are done in order to enable improvement and adjustment of the services according to the visitors’ wishes without destroying important natural values. The aim of this survey is to find out who visits the Ekenäs National Park and what their motives for the visit are as well as making information of the visitors and their opinions easily accessible for decision-makers and planners. This survey also takes a quick look at what economic impact the national park has on the vicinity. The method of this survey was partly guided questionnaires, which were handed out to the visitors in the national park. The answers were inserted into Metsähallitus’ database ASTA. The results show that the most important motive for the visit was to experience and enjoy nature, relax and just to stroll around. This result backs up results from similar visitor surveys done in other countries. Also sailing, swimming and visiting the kiosk were popular activities. The visitors were generally pleased with their visit and the satisfaction index is slightly better than the national equivalent. Most of those participating in the survey have visited the national park before and will most likely come again. Things that many visitors would like to see introduced in the national park are more and better toilets, a station for emptying the boat’s holding tank, better firewood at campfire sites and better transport service to the national park. An interesting difference between the results from 2007 and this year is that the visitors do not demand waste disposal service in the park. Language: Swedish
Opioid induced constipation in cancer patients: pathophysiology, diagnosis and treatment

ABSTRACT Opioid-induced constipation (OIC) has emerged as a major contributor to morbidity in cancer patients. OIC is common, difficult to treat and causes significant reductions in the quality-of-life of cancer patients. It results from opioid action on gut mu-receptors, which leads to the disruption of bowel motility, mucosal transport and defecation reflexes. Laxatives are cornerstone in the management of OIC despite their relatively limited effectiveness and lack of strong evidence supporting their use. In the past few years, novel therapeutics have emerged for the management of OIC. These include; prokinetic agents, peripherally-acting mu-opioid receptor antagonists (PAMORAs), secretagogues and opioid receptor agonist/antagonist combination tablets. This article will review the mechanism of OIC in cancer patients and describe the novel therapeutic options for its prevention and management.
Changes in the Bathymetry and Volume of Glacial Lake Agassiz between 9200 and 7700 14C yr B.P.

Abstract Computer reconstructions of the bathymetry of the lake were used to quantify variations in the size and form of Lake Agassiz during its final two phases (the Nipigon and Ojibway phases), between about 9200 and 7700 14C yr B.P. (ca. 10,300–8400 cal yr B.P.). New bathymetric models for four Nipigon Phase stages (corresponding to the McCauleyville, Hillsboro, Burnside, and The Pas strandlines) indicate that Lake Agassiz ranged between about 19,200 and 4600 km3 in volume and 254,000 and 151,000 km2 in areal extent at those times. A bathymetric model of the last (Ponton) stage of the lake, corresponding to the period in which Lake Agassiz was combined with glacial Lake Ojbway to the east, shows that Lake Agassiz–Ojibway was about 163,000 km3 in volume and 841,000 km2 in areal extent prior to the final release of lake waters into the Tyrrell Sea. During the Nipigon Phase, a number of catastrophic releases of water from Lake Agassiz occurred as more northerly (lower) outlets were made available by the retreating southern margin of the Laurentide Ice Sheet; we estimate that each of the four newly investigated Nipigon Phase releases involved water volumes of between 1600 and 2300 km3. The final release of Lake Agassiz waters into the Tyrrell Sea at about 7700 14C yr B.P. is estimated to have been about 163,000 km3 in volume.
Physical vulnerability modelling in natural hazard risk assessment

An evaluation of the risk to an exposed element from a hazardous event requires a consideration of the ele- ment's vulnerability, which expresses its propensity to suf- fer damage. This concept allows the assessed level of haz- ard to be translated to an estimated level of risk and is of- ten used to evaluate the risk from earthquakes and cyclones. However, for other natural perils, such as mass movements, coastal erosion and volcanoes, the incorporation of vulnera- bility within risk assessment is not well established and con- sequently quantitative risk estimations are not often made. This impedes the study of the relative contributions from dif- ferent hazards to the overall risk at a site. Physical vulnerability is poorly modelled for many rea- sons: the cause of human casualties (from the event itself rather than by building damage); lack of observational data on the hazard, the elements at risk and the induced dam- age; the complexity of the structural damage mechanisms; the temporal and geographical scales; and the ability to mod- ify the hazard level. Many of these causes are related to the nature of the peril therefore for some hazards, such as coastal erosion, the benefits of considering an element's physical vulnerability may be limited. However, for hazards such as volcanoes and mass movements the modelling of vulnerabil- ity should be improved by, for example, following the ef- forts made in earthquake risk assessment. For example, ad- ditional observational data on induced building damage and the hazardous event should be routinely collected and cor- related and also numerical modelling of building behaviour during a damaging event should be attempted.
Point-of-InterestDetectionforRangeData

Point-of-interest detection is a way of reducing the amount of data that needs to be processed in a certain application and is widely used in 2D image analysis. In 2D image analysis, point-of-interest detection is usually related to extraction of local descriptors for object recognition, classification, registration or pose estimation. In analysis of range data however, some local descriptors have been published in the last decade or so, but most of them do not mention any kind of point-ofinterest detection. We here show how to use an extended Harris detector on range data and discuss variants of the Harris measure. All described variants of the Harris detector for 3D should also be usable in medical image analysis, but we focus on the range data case. We do present a performance evaluation of the described variants of the Harris detector on range data.
NOTES AND CORRESPONDENCE Imbalance in a Mesoscale Vortex within a Midlatitude, Continental Mesoscale Convective System

The authors examine the degree of hydrostatic and gradient balances in a mesoscale convective vortex (MCV) in the stratiform region of a mesoscale convective system (MCS) that crossed Oklahoma on 1 August 1996. Results indicate that the MCV was partially unbalanced because the cool layer at the base of its core was too cool and too shallow to balance the tangential winds about the MCV’s axis. The apparent imbalance may have been due to strong, unsteady forcing on the vortex; insufficient or unrepresentative data; approximations used in the analysis; or reasons that are unknown.
Soils of Cape Vert and their classification according to the world reference soil base.

Studies regarding mapping and classification of soils in Cap Verde territory, as well as those which take into account land evaluation classification are identified. Such studies are typified and their potential integration in the current knowledge analyzed. Considering the available information on soil resources, it is concluded that it does not allow a simple transference to the universal taxonomic systems (including the World Reference Soil Data Base, WRB), given the inadequacy of data analysis and the absence of analytical information. Finally, the main actions to lead to the functional organization of the available information on soils of Cap Verde are outlined, considering agrarian development, management of territory, natural resources management and environmental quality.
The importance of reconciliation in education

The aim of this paper is to summarise existing evidence and new analyses that shed light on the role of reconciliation in schools and early learning services in particular, and in education more broadly. We present the first analysis in Australia of the relationship between racism/discrimination and cognitive development among the Indigenous Australian population, showing a negative and statistically significant longitudinal relationship. We discuss the policy implications of these findings, as well as the implication of the broader literature on reconciliation in schools and early learning services.
Significados que construyen niños, padres de familia y docentes vinculados a varias instituciones escolares de la ciudad de Bogotá sobre infancia, familia y escuela en el marco de la globalización

Esta investigacion estuvo dirigida a indagar sobre los significados construidos por ninos, padres de familia y profesores acerca de la infancia, la familia y la escuela en el contexto de la globalizacion. Se aplico una encuesta a un grupo de 73 ninos y ninas, 52 padres de familia y 52 docentes que se encontraban vinculados a varias instituciones escolares de la ciudad de Bogota. Los resultados mostraron convergencias y divergencias entre los tres grupos de participantes, en cuanto a la forma de significar la infancia y las interacciones escolares y familiares en la actualidad. En terminos generales, se observo que los ninos y, en menor grado, los padres de familia tienden a una valoracion positiva de los cambios asociados con la globalizacion, mientras que los profesores se inclinan hacia posturas mas criticas. El estrato socioeconomico sirvio como variable moderadora en algunos de los significados expresados por los tres grupos de participantes en el estudio. Se discute sobre las implicaciones de estos resultados, haciendo especial enfasis en las demandas y retos que afronta la escuela en el marco de la globalizacion. Palabras clave: significados, interacciones, infancia, familia, escuela, globalizacion.