Miracle-dz/UniFAR-FTUs huggingface dataset:
Stroke as a medical emergency in older people

In the last 20 years a realization has developed that acute stroke is a condition that benefits from early intensive investigation and treatment. Older people are historically less likely to receive such active management through a combination of limited evidence due to their exclusion from clinical trials and a level of ‘therapeutic nihilism’ regarding older subjects with severe, acute illness. There is increasing evidence that many acute therapies, including thrombolysis, benefit older stroke patients. Older subjects may not achieve as good results as younger groups but differential benefits are often comparable when expected outcomes are considered. Risk of haemorrhagic complications with thrombolysis is not substantially increased and older subjects are now receiving this therapy despite a dearth of relevant trial data. Intensive physiological monitoring and stroke unit care has been found to be of benefit to patients of all ages. Surgical options for intracerebral haemorrhage are limited, but there is little difference in the management of intracranial haemorrhage in older people. There is unlikely to be a benefit to surgical hemicraniectomy for cerebral infarction in those >60 years. In conclusion, active management for acute stroke in older people is frequently beneficial and age should not be a barrier to such care.
Free Radicals and Food Additives

parison ofdifferent series of patients. In contrast, the Kiel classification, used by most European histopathologists, is not mentioned. I would happily recommend several excellent atlases of haematology, but this is not one of them. Any reader interested in obtaining a useful reference and with the same amount of money to spend should browse through the shelves at a medical bookshop, and decide whether they prefer Haematological Cytology (Heyhoe and Flemens), An Atlas of Haematology (McDonald and Cruichshank) or The Sandoz Atlas of Clinical Haematology (Hoffbrand and Pettit). Nigel T.J. O'Connor Royal Shrewsbury Hospital, Shropshire SY3 8XF.
Anatomy of aging face

Why should wait for some days to get or receive the anatomy of aging face book that you order? Why should you take it if you can get the faster one? You can find the same book that you order right here. This is it the book that you can receive directly after purchasing. This anatomy of aging face is well known book in the world, of course many people will try to own it. Why don't you become the first? Still confused with the way?
Protective Ventilation vs. Hypercapnia for the Attenuation of Ventilator-Associated Lung Injury

Mechanically ventilated patients are at risk of developing Ventilator-Associated Lung Injury (VALI). Improved ventilation strategies by lung-protective settings may cause hypercapnia. This study investigated whether attenuation of VALI is attributed to protective ventilation with low tidal volume (VT) or hypercapnia. Lung injury was induced in rats by instillation of 1.25M HCl. Ten rats each were ventilated for 4 hours with: Conventional Normocapnia (highVT), Lung-Protective Ventilation (VT 8mL/Kg), Injurious Normocapnia (highVT, added dead space), Conventional Hypercapnia (highVT, inhaled CO2), Protective Hypercapnia (VT 8mL/Kg, inhaled CO2) and Permissive Hypercapnia (VT 8mL/Kg, hypoventilation). Lung-Protective Ventilation reduced pulmonary edema compared to Conventional and Injurious Normocapnia. Therapeutic hypercapnia reduced alveolar damage and inflammation by reducing IL-6 and MCP-1 in the lung, and IL-1 and TNFsystemically. Therapeutic hypercapnia may be more effective in attenuating some of the biomarkers of VALI and protecting the lung than protective ventilation alone.
Greybox design methodology: A program driven hardware co-optimization with ultra-dynamic clock management

In this paper, a novel Greybox design methodology is proposed to establish a design and co-optimization flow across the boundary of conventional software and hardware design. The dynamic timing of each software instruction is simulated and associated with processor hardware design, which provides the basis of ultra-dynamic clock management. The proposed scheme effectively implements the instruction-based clock management and achieves 21.71% frequency speedup. Besides, a novel program-driven hardware optimization flow is proposed, in which software operations are mapped with hardware gate netlist and sorted by the usage frequency. The experiments on an ARM based pipeline design in commercial 65nm CMOS process show an extra 10% frequency speedup is obtained with high optimization efficiency. Overall, the proposed Greybox design method achieves frequency speedup by 31.56%, comparing with conventional design method.
Microbiological, proximate analysis and sensory evaluation of baked product from blends of wheat-breadfruit flours.

The possibility of making bread of good nutritional, microbiological and sensory qualities from blends of wheat-breadfruit flours was examined. Blends of wheat flour (WF) with percentages of 0, 5, 10, 15, 20 and 25 of breadfruits flour (BF) were used in the production process. The proximate analysis, sensory evaluation and aerobic plate count (APC) of the bread samples were determined. The result of the proximate analysis of the whole wheat bread (WWB) and composite bread samples showed that crude protein contents (%) of 7.54 was recorded for the WWB while 7.33, 7.06, 6.97, 6.81 and 6.72 were recoded for the 5, 10, 15, 20 and 20 % breadfruit-wheat composite bread (BWCB). This shows that the crude protein decreased with increase in the BF substitution levels. A contrast trend was observed in the crude fibre contents (%) with the lowest value of 0.04 being recorded for the WWB and the highest value of 3.27 was obtained for the 25% BWCB. The ether extract (%) also decreased with corresponding increase in the BF levels, the WWB had the highest value of 1.10 while the lowest content of 0.75 was recorded for the 25% BWCB. The percentage ash contents of 0.65, 0.95, 1.14, 1.22, 1.41 and 1.70 were obtained for the percentages of 0, 5, 10, 15, 20 and 25 BF substitution levels. A similar trend was observed in the moisture content (%), ranging from 30.50 and 33.97. The percentage carbohydrate contents decreased with increase in the BF substitution, with the highest value of 60.17 being recorded for the WWB (0% BF Level). The sensory evaluation indicated that the composite breads were not significantly different (p Keywords : breadfruit, proximate analysis, composite bread AJFAND Vol. 8 (2) 2008 pp. 192-203
A New Angiostrongylid (Nematoda) Species from the Pulmonary Arteries of Akodon azarae (Rodentia: Cricetidae) in Argentina

Angiostrongylus morerai n. sp. (Nematoda: Angiostrongylidae) is described from the pulmonary arteries of Azara's grass mouse Akodon azarae (Rodentia: Cricetidae) in Argentina. It is distinguished from its congeners principally by the morphology of the dorsal ray, which is as long, or longer, than the externodorsals and has 2 long branches; the spicule lengths are also greater (400–465 μm). This is the first record of a metastrongyloid from sigmodontine rodents in Argentina.
Searchable Symmetric Encryption

Searchable Symmetric Encryption (SSE) when deployed in the cloud allows one to query encrypted data without the risk of data leakage. Despite the widespread interest, existing surveys do not examine in detail how SSE’s underlying structures are designed and how these result in the many properties of a SSE scheme. This is the gap we seek to address, as well as presenting recent state-of-the-art advances on SSE. Specifically, we present a general framework and believe the discussions may lead to insights for potential new designs. We draw a few observations. First, most schemes use index table, where optimal index size and sublinear search can be achieved using an inverted index. Straightforward updating can only be achieved using direct index, but search time would be linear. A recent trend is the combinations of index table, and tree, deployed for efficient updating and storage. Secondly, mechanisms from related fields such as Oblivious RAM (ORAM) have been integrated to reduce leakages. However, using these mechanisms to minimise leakages in schemes with richer functionalities (e.g., ranked, range) is relatively unexplored. Thirdly, a new approach (e.g., multiple servers) is required to mitigate new and emerging attacks on leakage. Lastly, we observe that a proposed index may not be practically efficient when implemented, where I/O access must be taken into consideration.
Prevalence and Symptoms of Idiopathic Hypercalciuria in Primary School Children of Tehran

Objective: Determining prevalence of idiopathic hypercalciuria (IH) in primary school children of Tehran. Material & Methods: We evaluated 778 primary school children (age 6-11, mean 9.1 years) in two steps: first (Screening test), we measured urine calcium to urine creatinine ratio (UCa/UCr) and in the second step (Definitive test), for those children who had UCa/UCr ratio more than 0.21 mg/mg we measured 24 hours urine calcium excretion. Children with secondary forms of hypercalciuria were excluded from the study. Children with idiopathic hypercalciuria were evaluated for manifestations of IH. Findings: Among 778 children, 195 (25.1%) had UCa/UCr ratio more than 0.21 mg/mg, but from these 195 children only 128 children delivered 24 hours urine samples. Among these 128 children for whom 24 hours urine calcium measurements were done 28 children excreted more than 4mg/kg/day calcium without hypercalcemia or any other known causes of hypercalciuria and we defined them as having idiopathic hypercalciuria. If all 195 suspicious cases of IH had delivered 24-hrs urine samples we would have 42 cases of IH. Conclusion: Prevalence of IH in our children was 5.4% and its manifestations were: hematuria, dysuria, recurrent abdominal pain, urinary incontinence, urgency, urinary tract infections and urolithiasis.
The role of IL-10 in preventing food-induced anaphylaxis

Background: Food allergy is a common condition resulting in a much impaired quality of life. So far, no clearly effective preventive and therapeutic strategies have been established. However, several options have been tested with promising results. Objective: This review examines the potential of various strategies involving an IL-10-mediated effect for tolerance induction to food antigens, mostly for preventing food allergy. Methods: In addition to a review of the literature, we describe and comment on experiments involving a Lactoccocus lactis strain transfected to secrete murine IL-10 directly into the gut. Results/conclusion: This strain was efficient at preventing subsequent sensitization with a common food allergen. There appears to be a potential for such strategies for the prevention of human food allergy but further investigations will be needed to explore them.
Microencapsulación de tramadol en ácido poliláctico mediante secado por aspersión

An interesting subject for pharmaceutical industry is the search of technologies to achieve pharmaceutical ways for administration and transportation of cytostatics, anti-inflammatories, peptides and hormones among other drugs implicating a reduction of its toxicity or a contolled releasing of active principle to increase its effectiveness. In present paper authors studied the influence of fluid flow in feeding, of atomization air and of driying; different physicochemical and morphological features (size, shape, porosity and distribution in the particles size, and the effectiveness of active principle encapsulation) of Tramadol's microspheres. As result, it was possible to achieve microspheres of 18.93 ± 2.31 μm with an spherical shape, a non-porous surface demostrating it by X-ray difractometry and Tramadol encapsulation in the polymer.
Initiation of reaching when standing with and without DAFOs in children with spastic diplegia

We investigated whether the use of dynamic ankle foot orthoses (DAFOs) can improve the coordination between standing posture and a reaching movement. We investigated the temporal sequence between onset of center of pressure (CoP) displacement and onset of hand displacement by means of two AMTI force plates and a two-camera optoelectronic system (ELITE). The task was to reach for a cup. Reflective markers were placed on hand, trunk and the cup. Four children with spastic diplegia and eight control children (aged 5–12) participated. They were tested wearing DAFOs (diplegia) and the results were compared with wearing shoes (diplegia and control). The children with spastic diplegia were able to make use of anticipatory changes in CoP displacement. The results indicated that more trials in children with spastic diplegia had CoP onset preceding hand onset while wearing DAFOs (18/20) than when wearing only shoes. More trials (27/40) during the 20% reaching condition in the control group had CoP onset preceding hand onset than during the 10% reaching condition (18/40). In spite of different amounts of assistance, anticipatory postural adjustments were found in the diplegia group. Use of anticipatory postural adjustments was not consistent in the control group. Practice of reaching during standing can be carried out with DAFOs and/or hand support, and can promote motor learning of anticipatory postural adjustments.
Evolution of neural networks

Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for third-party components of this work must be honored. For all other uses, contact the Owner/Author. GECCO ’18 Companion, July 15-19, 2018, Kyoto, Japan 2018 Copyright is held by the owner/author(s). ACM ISBN 978-1-4503-5764-7/18/07. https://doi.org/10.1145/3205651.3207857
Determinants of the Level of Care Provided for Various Types and Sizes of Dogs in New Providence, The Bahamas

This paper reports the level of care offered 424 dogs, classified as small dogs, large dogs, pit bulls and potcakes (the colloquial name for the local mongrel) in New Providence, The Bahamas. Levels of care that meet the legal minimum –food water and shelter– as well as care considered essential and enriched in The Bahamas were less common for large dogs than small dogs. Small dogs tended to get more care than other dogs and so were at lowest risk of being neglected. It is suggested that the size of the dog is an important factor which determines the level of care provided. Pit bulls generally received similar care to potcakes which are often considered neglected. Large dogs were more likely to be kept outside and less likely to be allowed inside the home than small dogs. It is conjectured that in many instances the level of care offered constitutes partial abandonment due to a lack of interaction between caregivers and their dogs.
Filial Responsibility in the Welfare State

In the Norwegian welfare state, the traditional role of adult children as service providers to their aging parents exists side by side with a new role as mediator with the service bureaucracy. A random sample of 500 Norwegian elderly, living at home, was interviewed about the help they receive from public and private sources. This study shows that despite the high level of public services, adult children play an active part in caring for parents. State provision of help is shown to have no effect on daughters'service provision, but a slight negative effect on sons'help. The distribution of home help services suggests an additional role for children in securingparents this important service. Adult children, except for daughters living close by, appear to increase parents'access to public home help in the early phases of disability.
A New Genus of Cystidicolid Nematode From the Stomach of Galaxias maculatus (Osmeriformes: Galaxiidae) in Patagonia (Argentina)

Abstract During a parasitological survey of Galaxias maculatus (Jenyns) from Patagonian Andean Lakes, specimens of a new species of nematode were collected from the stomach of fish and studied by light and scanning electron microscopy. This species is described as the only member of a newly proposed genus of Cystidicolidae by having oral opening dorsoventrally elongated, 2 lateral pseudolabia, 4 cephalic papillae, stoma (vestibule) elongated, esophagus divided into anterior muscular and posterior glandular sections, and caudal alae in males. Placonema n. gen. (Habronematoidea, Cystidicolidae) is characterized by the combination of the following features: oral opening dorsoventrally elongated demarcated by 4 sclerotized plates and 2 well-developed pseudolabia projected to the buccal cavity, each pseudolabium with conspicuous, conical, anterior protuberances. Four cephalic papillae and deirids simple. Male with caudal alae, area rugosa absent, 4 pairs of preanal papillae, unpaired papilla present on anterior cloacal lip, and 6 pairs of postanal papillae. Larvigerous eggs without filaments. Placonema pataguense n. gen. n. sp. infects the stomach of G. maculatus from Lake Patagua (Patagonia, Argentina) and is the first species of Cystidicolidae described from G. maculatus.
Building a better heuristic for the traveling salesman problem: combining edge assembly crossover and partition crossover

A genetic algorithm using Edge Assemble Crossover (EAX) is one of the best heuristic solvers for large instances of the Traveling Salesman Problem. We propose using Partition Crossover to recombine solutions produced by EAX. Partition Crossover is a powerful deterministic recombination that is highly exploitive. When Partition Crossover decomposes two parents into q recombining components, partition crossover returns the best of 2q reachable offspring. If two parents are locally optimal, all of the offspring are also locally optimal in a hyperplane subspace that contains the two parents. One disadvantage of Partition Crossover, however, is that it cannot generate new edges. By contrast, the EAX operator is highly explorative; it not only inherits edges from parents, it also introduces new edges into the population of a genetic algorithm. Using both EAX and Partition Crossover together produces better performance, with improved exploitation and exploration.
A Curriculum Outline for and Advanced Certificate of Professional Development in TEFL/TESOL Teacher Training

Intensive Transition Program in English for Speakers of Other Languages The University of Hawaii’s Kapi’olani College examined the viability of establishing a program offering an Advanced Certificate of Professional Development in TEFL/TESOL Teacher Training. This paper will present aspects of the development of the curriculum for the certificate and describe the framework in which the certificate was initially implemented at one of the college’s partner institutions, Youngsan University/University of Hawaii International Education Institute (YSU/UH-IEI), in Ulsan, Korea.
Analysis of Schistosoma mansoni Population Structure Using Total Fecal Egg Sampling

Abstract Many parasite populations are difficult to sample because they are not uniformly distributed between several host species and are often not easily collected from the living host, thereby limiting sample size and possibly distorting the representation of the population. For the parasite Schistosoma mansoni, we investigated the use of eggs, in aggregate, from the stools of infected individuals as a simple and representative sample. Previously, we demonstrated that microsatellite allele frequencies can be accurately estimated from pooled DNA of cloned S. mansoni adults. Here, we show that genotyping of parasite populations from reproductively isolated laboratory strains can be used to identify these specific populations based on characteristic patterns of allele frequencies, as observed by polyacrylamide gel electrophoresis and automated sequencer analysis of fluorescently labeled PCR products. Microsatellites used to genotype aggregates of eggs collected from stools of infected individuals produced results consistent with the geographic distribution of the samples. Preferential amplification of smaller alleles, and stutter PCR products, had negligible effect on measurement of genetic differentiation. Direct analysis of total stool eggs can be an important approach to questions of population genetics for this parasite by increasing the sample size to thousands per infected individual and by reducing bias.
Putting aggression into context: An investigation into contextual factors influencing the rate of aggressive incidents in a psychiatric hospital

The contribution of contextual factors to aggressive incidents in psychiatric hospitals has tended to be ignored. This study used a functional analysis framework to investigate 130 incidents. Staff interviews were used to identify antecedents and management strategies employed. Reported aggression rates varied greatly between wards including those serving similar functions. No difference was found between the number of aggressive incidents reported by the secure units and admission wards when compared with other wards. When compared with each other, the two secure units and two admission wards reported significantly different numbers of incidents (p<0.001 and p<0.01, respectively). Staff victims were more likely to be male than female (p<0.01). Incidents in general were more likely to be preceded by 'external' than 'internal' antecedents (p<0.05). More incidents were managed with physical than verbal interventions (p<0.001). The findings suggest that environmental and interpersonal variables may have infl.
Patients' satisfaction with stroke services

Patient satisfaction with stroke services is a key aspect of the evaluation of the quality of services but there are no adequate means of assessing satisfaction in this area. A questionnaire derived from in-depth interviews was piloted on two samples. The resulting questionnaire consisted of two sections, one on inpatient services (Hospsat) and the other on services in the community (Homesat). It was sent to 219 patients, who had had a stroke six months previously, along with postal versions of the Barthel ADL index, the Nottingham Extended ADL Scale, the Nottingham Health Profile, the short form of the Geriatric Depression Scale and the Faces Scale. The response rate for the questionnaires was 87%. Test-retest reliability and tests of internal consistency of the satisfaction scales were carried out on a subsample of this population. Convergent and discriminant validity were explored by examining correlations with the above measures. The satisfaction questionnaire had construct validity with significant correla tions between the Barthel ADL Index (r = 0.39), the Nottingham Extended ADL Scale (r= 0.38) and the physical mobility subsection of the Nottingham Health Profile (r= -0.36). Internal consistency was high for both sections (Cronbach's Alpha: Hospsat 0.86; Homesat 0.77). Test-retest reliability was fair; the mean difference for total scores was 0.59 (SD = 2.4) for Hospsat, and 0.32 (SD = 2.1) for Homesat. A high level of dissatisfaction was uncovered. Just under half (48%) of people were dissatisfied with some aspect of the care they received in hospital and over half (53%) were dissatisfied with some aspect of the services they received in the community. The highest rate (54%) of dissatisfaction was with the amount of therapy received. Good patient satisfaction measures are useful since they complement 'objective' outcome measures and may highlight areas in need of evaluation and improvement.