Miracle-dz/UniFAR-FTUs huggingface dataset:
KORELASI ANTARA EKSPRESI PROTEIN CYCLOOXYGENASE-2 (COX-2) DENGAN DERAJAT DIFERENSIASI KARSINOMA SEL SKUAMOSA SERVIKS UTERI

ABSTRAK Karsinoma serviks uteri yang paling banyak dijumpai adalah karsinoma sel skuamosa (75%). Beberapa penelitian telah menunjukkan pengaruh aktivitas cyclooxygenase-2 (COX-2) selama karsinogenesis dan ekspresi berlebih pada banyak jenis keganasan. Penelitian ini adalah untuk memeriksa ekspresi protein COX-2 dan korelasinya dengan derajat diferensiasi karsinoma sel skuamosa serviks uteri. Sampel yang dianalisa meliputi : 45 blok parafin dari pasien karsinoma sel skuamosa serviks uteri, terdiri 15 sampel karsinoma sel skuamosa serviks uteri berkeratin , 15 sampel karsinoma sel skuamosa serviks uteri tidak berkeratin tipe sel besar dan 15 sampel karsinoma sel skuamosa serviks uteri tidak berkeratin tipe sel kecil. Analisis imunohistokimia dilakukan menggunakan anti bodi monoklonal COX-2. Hasil penelitian diperoleh ekspresi protein COX-2 positif pada 37,8% karsinoma sel skuamosa serviks uteri, tetapi tidak terdapat korelasi yang signifikan antara COX-2 dengan derajat diferensiasi (p = 0,422). Ekspresi berlebih protein COX-2 dijumpai pada karsinoma sel skuamosa serviks uteri berkeratin dan karsinoma sel skuamosa serviks uteri tidak berkeratin, namun karsinoma sel skuamosa serviks uteri tidak berkeratin tipe sel kecil menunjukkan ekspresi yang sedikit dan rendah. Hasil ini menunjukkan bahwa peningkatan ekspresi COX-2 berperan penting sebagai fenomena awal proses karsinogenesis pada karsinoma sel skuamosa serviks uteri. Kata kunci: Cyclooxygenase (COX-2); Derajat diferensiasi; karsinoma sel skuamosa serviks uteri ABSTRACT The most common carcinoma of the uterine cervix is squamous cell carcinoma (75%). Numerous studies have emphasized the importance of cyclooxygenase-2 (COX-2) activity during carcinogenesis and overexpressed in any kind of malignancies. The purpose of this study was to investigate the expression of protein COX-2 and its correlation with the differentiation grading in squamous cell carcinoma of the uterine cervix. The following samples were analyzed: 45 paraffin tissue blocks from patients with squamous cell carcinomas of the uterine cervix, including 15 samples of keratinizing squamous cell carcinomas, 15 samples of large cell non keratinizing squamous cell carcinomas and 15 samples of small cell non keratinizing squamous cell carcinomas. Immunohistochemical analysis was performed with a rabbit monoclonal antibody against human COX-2. Expression of protein COX-2 was positive in 37,8% of squamous cell carcinoma of the uterine cervix, but there was no a significant correlation between COX-2 with the differentiation grading (p = 0,422). Overexpression of protein COX-2 was found in both keratinizing squamous cell carcinoma and non keratinizing squamous cell carcinoma, but small cell non keratinizing squamous cell carcinomas showed infrequent and low expression. These results suggested that increased COX-2 expression might play an important role as early phenomena in carcinogenesis of squamous cell carcinoma. Keywords: Cyclooxygenase (COX-2); Differentiation grading; Squamous cell carcinoma
Pausing strategies with regard to speech style

Speech is occasionally interrupted by silent and filled pauses of various length. Pauses have many different functions in spontaneous speech (e.g. breathing, marking syntactic boundaries as well as speech planning difficulties, time for self-repair). The aim of the study was the analysis of the interrela-tion between the temporal pattern and the syntactical position of silent pauses (SP) on one hand. On the other hand, filled pauses (FP) were also analyzed according to their phonetic realization, as well as the combination of SPs and FPs. The effect of speech style on pausing strategies was also analyzed. A narrative recording and a conversational recording from 10 speakers (ages between 20 and 35 years, 5 male, 5 female) were selected from Hungarian Spontaneous Speech Database for the study. The material was manually annotated, silent pauses were categorized, then the duration of pauses were extracted. Results showed that the position of silent and filled pauses affects their duration. The speech style did not influenced the frequency of pauses. However, silent and filled pauses were longer in narratives than in conversations. Results suggest that pausing strategies are similar in general; however, the timing patterns of pauses may depend on various factors, e.g. speech style.
Nephrotic Syndrome in Leishmaniasis

A 34-year-old white homosexual man presented with advanced human immunodeficiency virus disease and nephrotic syndrome. A renal biopsy demonstrated leishmania organisms in the interstitium and glomeruli, and membranoproliferative glomerulonephritis. Treatment with highly active antiretroviral therapy and liposomal amphotericin led to parasitological clearance and improvement in proteinuria, although treatment discontinuation later led to clinical and parasitological relapse.
Disciplinary Literacy: From Infusion to Hybridity

This article argues that for disciplinary literacy to be addressed successfully by subject-area teachers and students, it needs to choose a different path than the one it has been on. It explains how the road disciplinary literacy has traveled to date has been marked by justifiable subject-area teacher resistance to requirements to infuse literacy teaching and learning strategies into their teaching without regard for disciplinary epistemologies or local perspectives. It argues for an alternative approach that immerses literacy experts in the hybridity of classroom disciplinary learning spaces with respect for literacy and disciplinary discourses as well as school and community subcultural beliefs, practices, and resources. It examines the ways such hybridity has been addressed by disciplinary literacy researchers in the Journal of Literacy Research to date, and it offers recommendations for advancing research, practice, and policy.
Me or We? The Effect of Team and Individual Sports Activity on Executive Functioning

There is limited research examining the processes by which open and closed motor skill sports optimize Executive Functions (EFs). The aim of the present study was to examine the effects of motor sequencing and repetitive movement in individual and team sports and their influence on EFs. The study also investigated gender differences in EF abilities within a sporting context. We tested 40 University students (17 = Male, 23 = Female) aged 17-29 (M = 20.47, SD = 2.75) who were randomly assigned to a team and individual sports-oriented intervention focused on either repetitive or variable motor sequential movement. We predicted that individuals in the variable motor sequencing and team condition would yield the best EF performance. Our results suggested a significant interaction effect of Gender x “Team/Individual” on EF measures, as females and males performed significantly different on a team compared to those in the individual conditions. For performance of intervention, we found an overall main effect of Team/Individual, such that participants in the Team conditions finished faster on the sports task than those in the Individual conditions. A significant main effect of Gender was also found, as males generally outperformed female participants. These findings have implications for optimizing sport and EF performance between genders. TEAM & INDIVIDUAL SPORTS ACTIVITY ON EF 4
Exploration of Factors that Contribute to a Successful Work Experience for Adults who are Visually Impaired

ance Service. Thorndike, R. , Hagen, E. , & Sattler, J. (1986). The Stanford-Binet Intelligence Scale, 4th edition. Chicago: Riverside. Tulsky, D. , Zhu, J., & Ledbetter, M. (1997). WAIS-III/WMS-III technical manual. San Antonio, TX: Psychological Corporation. Vander Kolk, C. (1977) Intelligence testing for visually impaired persons. Journal of Visual Impairment & Blindness, 71, 158-163. Ward, M. , & Genshaft, J. (1983). The PerkinsBinet Test: A critique and recommendations for administration. Exceptional Children, 49, 450-452. Wechsler, D. (1989). Wechsler Preschool and Primary Scales of Intelligence, Revised. San Antonio, TX: Psychological Corporation. Wechsler, D. (1992). Wechsler Intelligence Scale for Children, 3rd edition. San Antonio, TX: Psychological Corporation. Wechsler, D. (1997). Wechsler Adult Intelligence Scale, 3rd edition. San Antonio, TX: Psychological Corporation. Woodcock, R. , McGrew, K. , Mather, N. , & Schrank, F. (2001). Woodcock-Johnson Psychoeducational Battery, 3rd edition. Itasca, IL: Riverside.
Developments in language education : a memorial volume in honour of Sauli Takala

In his article “From a young student to an expert in his field”, Erkki Kangasniemi, former director of the Finnish Institute for Educational Research (FIER), gives an account of Sauli Takala as a student and a colleague. Sauli, Erkki and a close friend and colleague of Sauli’s, Liisa Havola, all started their studies in 1961 at the University where Sauli studied English and Swedish. Sauli was a very diligent student who wanted to achieve the highest grade on every examination he took – and he was usually successful in this. On one occasion, Sauli failed to get the grade he thought he deserved on a phonetics examination; he took the study books with him to the lecturer and by showing how he had used them to answer the questions he succeeded in persuading the lecturer to raise his grade to a level that satisfied Sauli. Sauli Takala graduated from the university in 1970. To fund his living expenses during his studies, he worked as a part-time language teacher in different schools on several occasions. He also completed pedagogical studies to have the formal language teacher’s qualifications. Sauli started his career as a researcher already while studying (which probably explains why it took him almost ten years to graduate). From 1966 onwards Sauli worked at the FIER in various projects that paved the way for the introduction of comprehensive education in Finland (that happened in stages in the 1970s). Sauli specialised in investigating language education and curriculum design. In those days, as Erkki Kangasniemi reminisces, the national educational authorities did not consider researchers and research findings as something very useful for educational planning. Research results were often ignored, if they were at odds with what the existing laws and regulations about education stated. Starting in 1971, both Sauli and Erkki began to work as research assistants in the new unit within the FIER that focused on conducting evaluations of educational achievement in the schools that trialled comprehensive education, often comparing the findings with those obtained in the traditional ‘middle schools’ that represented the old, selective educational system. The introduction of the comprehensive school in Finland was a highly political issue: there were widespread arguments that not everybody can study according to the same curriculum till grade 9 (which marks the end of compulsory education in the new system) and that not everybody can learn a foreign language
THE THEORY OF AFFORDANCES – AN INSPIRATION FOR ERGONOMICS

In the paper I am at presenting philosophically reach theory of affordances as a way of extending the range of research methods used in ergonomics. In the paper I am concern with the fundamentals of the theory of affordances as presented originally by Gibson (1977, 1979) and developed by Heft (1989). I highlight philosophically significant aspects of the classical theory of affordances and propose further topics for investigation. I also propose introduction of the notion of rigid affordance for the special class of affordances important for ergonomics. TEORIA AFORDANCJI – INSPIRACJĄ DLA ERGONOMII
Women's Education, Autonomy and Reproductive Behaviour: Experience from Developing Countries.

Women's access to education has been recognized as a fundamental right. At the national level, educating women results in improved productivity, income, and economic development, as well as a better quality of life, notably a healthier and better nourished population. It is important for all kinds of demographic behaviour, affecting mortality, health, fertility, and contraception, The personal benefits that women attach to education vary widely according to region, culture, and level of devlopment, but it is clear that educaiton empowers women, providing them with increased autonomy and resulting in almost every context in fewer children. Beyond these few general assertions, however, there is little consensus on such issues as how much education is required before changes in autonomy or reproductive behaviour occur; whether the education-autonomy relationship exists in all cultural contexts, at all times, and at all levels of development; and which aspects of autonomy are important in the relationship between education and fertility. It is in the need to address these fundamental issues that this book took shape. The author reviews the considerable evidence about education and fertility in the developing world that has emerged over the last twenty years, and then passes beyond the limits of previous studies to address three major questions: BL Does increased education always lead to a decrease in the number of children, or is there a threshold level of education that a woman must achieve before this inverse relationship becomes apparent? BL What are the critical pathways influencing the relationship of women's education to fertility? Is fertility affected because education leads to changes in the duration of breast-feeding? Because it raises the age at marriage? Because it increases the practice of contraception? Or because education reduces women's preferences for large numbers of children? BL Do improvements in education empower women in other areas of life, such as their improving exposure to information, decision-making, control of resources, or confidence in dealing with family and the outside world? Supported by full documentation of the available survey data, this study concludes that such contextual factors as the overall level of socio-economic development and the situation of women in traditional kinship structures complicate the general assumptions about the interrelationships between education, fertility, and female autonomy. It lays out the policy implications of these findings and fruitful directions for future research.
Secular changes in child marriage and secondary school completion among rural adolescent girls in India

Background Child marriage (<18 years) and school drop-out disproportionately affect girls living in impoverished households in rural areas, with long-term economic and health consequences. Improving retention in education, and delaying age at marriage and first pregnancy have received substantial attention at the national and global level, in line with the Millennium Development Goals and the Sustainable Development Goals (SDGs) (2015-2030). Methods We examined changes over time in economic, education and child marriage indicators among adolescents from rural households in (i) Northern Karnataka (the most deprived region of Karnataka), (ii) Karnataka state, and (iii) all India, using individualized data from four pre-existing, nationally-representative datasets (District Level Household and Facility Surveys (DLHS 2-4) (2002/4–2012/3) and the National Family Health Survey (NFHS-4) (2015-16)). Results At the national and state level, we found large improvements in secondary educational attainment among girls and boys living in rural settings (proportion of adolescents completing age-appropriate secondary school education (all India): girls 12.4% 2002/3 vs. 31.6% 2015/6; boys 18.9% 2002/4 vs. 36.8% 2015/6). We also observed large reductions in child marriage and early child-bearing rates (proportion of married women aged 18-24 years married <18 years: 62.4% 2002/4 vs. 23.8% 2015/6; proportion of married girls aged <19 years who are pregnant or have children: 62.4% 2002/4 vs. 21.9% 2015/6). In addition, we found evidence of “clustered deprivations”, whereby girls in rural areas from the poorest families and lowest castes continue to experience multiple forms of disadvantage, with child marriage significantly associated with scheduled caste / scheduled tribe (SC/ST) caste (odds ratio (OR)=1.25, 95% confidence interval (CI)=1.18-1.32), poorest quintile (OR=2.38, 95% CI=2.21-2.55) and illiteracy (OR=2.09, 95% CI=1.95-2.23); and not completing secondary education significantly associated with SC/ST caste (OR=1.52, 95% CI=1.45-1.59), poorest quintile (OR=4.17, 95% CI=3.90-4.46), and child marriage (OR=2.05, 95% CI=1.85-2.26). Conclusions The results show substantial improvements in economic, educational and child marriage indicators at the state and national level over the past 14 years. The government has implemented multiple programmes and policies to address child marriage and school drop-out, and these trends suggest such efforts may be having a positive impact. If India is to achieve the SDGs, designing targeted interventions to reach those who continue to be left furthest behind is going to be key.
ESDN Quarterly Report September 2009 Sustainable development strategies beyond Europe

This Quarterly Report (QR) focuses on sustainable development strategies beyond Europe in order to provide an overview of strategic policy documents for sustainable development in countries of various world regions. After outlining some basic international developments with regard to national sustainable development strategies (NSDSs) and different types of NSDSs, the QR provides an overview of selected sustainable development strategies of countries in the Asian & Pacific region, South and Latin America & the Caribbean, North America and the non-European Mediterranean region. In total, 16 countries and two regional cooperations (Pacific Islands Forum, Mediterranean Strategy for Sustainable Development) are covered in the QR. For each country, the QR provides background information, lists the objectives and topics of the sustainable development strategy, includes information on responsible institutions and on implementation processes, and shows how efforts of strategy delivery are monitored and evaluated. Finally, the QR presents some concluding remarks on similarities and differences among these countries and regions.
Uncommon Gynecological Pathologies We Had Encountered - A Histopathological Potpourri. -

Background: Gynecological surgeries are done for both benign and malignant conditions involving the uterus, cervix, tubes, ovaries, vagina and vulva. Very few rare entities are seen in the gynaecopathological practice. Aim: To analyze the uncommon benign and malignant entities diagnosed in the gynecological specimens. Materials and Methods: During our one year study period, all the gynecological specimens were retrieved from the records. Rarely encountered specimens were included in our study after reanalysis. The histomorphology and the differential diagnosis are discussed. Results: Out of 3100 gynecological specimens we received, few rare benign and malignant conditions were diagnosed. Most of them were incidental findings. The commonest presenting symptom was abdominal pain and the provisional diagnosis was leiomyoma in most of the cases. Ten interesting cases were diagnosed during our study period. Brief review of literature and differential diagnosis of these rare entities are discussed. Conclusion: Rare entities like pure lipomatous lesion of the uterus and adenocarcinoma of mammary gland like arising from hidradenoma papilliferum were encountered during our study period. Diagnostic criteria’s of these rare tumors and the review of literature gave us a true learning experience.
Usage of teaching aids in increasing cognition among slow learners through art lessons

This study was conducted to determine the effectiveness of using electronic and non-electronic teaching aids in improving the cognitive levels among slow learners through art lessons. The research method used was the Hermeneutic method in which the daily lesson plans and the observations of students’ artworks were analyzed. This research was carried out in a school in Kuala Kangsar district and about nine slow-learners were involved in the study as the sample. The students’ cognitive level could be improved through the subject of Art and the development of their psychomotor skills could be improved through making handicrafts. From this research, the results obtained showed that the use of electronic and non-electronic teaching aids positively affected the improvisation of a student’s cognitive level and psychomotor skills among slow learners.
A Retrospective Study of the Incidence of GIST in Scotland from 1995 to 1999

Background and aims: Gastrointestinal Stromal Tumours (GIST) are mesenchymal soft tissue neoplasms which express the c-kit receptor and are exquisitely sensitivity to tyrosine kinase receptor inhibitors such as imatinib. This has significantly improved prognosis so it is important to identify retrospective cases. Methods: Patients between 1995-1999 with suspected GIST were identified via Scottish pathology departments. C-kit + and C-kit -/CD34 + tumours were included. Data were analysed according to NIH consensus and the newer AFIP criteria. Results: The incidence of GIST was 0.69/100000/year. 44.8% were originally diagnosed as GISTs. Using NIH Consensus criteria there was a statistically significant relationship between overall survival and necrosis (p=0.004), prognostic group (p<0.0001) and mitotic rate (p=<0.0001). Overall survival was correlated with AIFP criteria (p value <0.0001). Conclusion: This pan Scotland study validates the AFIP criteria for assessment of overall survival in GISTs. In addition using the established NIH consensus criteria confirms a similar incidence to other European countries. We have identified patients who are eligible for targeted therapies who would otherwise have been missed.
Phlegmasia cerulea dolens in the upper extremity

P hlegmasia cerulea dolens is a rare condition with devastating complications that can lead to amputation of the affected limb and even death. It results from acute massive venous thrombosis and obstruction of the venous drainage of an extremity. It is most commonly found in the lower extremities, but can occur in the upper extremities. Few reports on this condition in the upper extremity exist, and timely recognition is crucial because immediate treatment may lead to an improved outcome. This case report describes a patient with a known thrombophilic disorder, who was being treated for phlegmasia cerulea dolens and developed postphlebitic sequelae leading to a forearm compartment syndrome. Informed consent was obtained from the patient.
The problem of unwanted online publication and use of images of children and young people : A legal challenge

5 CHAPTER ONE – INTRODUCTION, OBJECTIVES AND SCOPE . 7 I Chapter Introduction . 7 II Background . 7 A Images and Cyberbullying . 11 B Images, Privacy and Control . 12 III Scope . 17 A Images . 17 B Images and the Internet . 24 C Children and Young People . 30 IV Research Questions and Objectives . 33 V Framework and Research Method . 34 VI Thesis Outline . 36 A Chapter Division . 36 1 What is the Problem You are Trying to Solve? 36 2 Why is Government Action Needed? 37 3 What Policy Options are you Considering, What is the Likely Benefit of Each and Which is the Best Among Those Considered? 37 VII Significance of Research and Original Contribution to Knowledge . 38 VIII Chapter Summary . 40 CHAPTER TWO –THE IMPACT OF IMAGES ON CHILD DEVELOPMENT . 43 I Introduction and Chapter Outline . 43 II Images and Harm: Gaps in the Literature . 44 III Framework and Research Scope . 50 IV Self‐Concept and Self‐Esteem . 54 A The Meaning and Importance of Self‐Esteem . 55 B Influences on Self‐Esteem . 59 1 Perceptions of How Others See Us . 59 2 Self‐Esteem and Appearance . 62 3 Images, Impression Management and Self‐Esteem . 67 (a) Context Collapse . 71