Miracle-dz/UniFAR-FTUs huggingface dataset:
A study on wave equation and solutions of shallow water on inclined channel

Viscous debris flow in China is well known as lots of intermittent surge flows. These intermittent surge flows are observed not only in China of viscous debris flow but also in the European Alps and other mountains region. But the characteristic of wave motion has not been made clear. It is important to obtain wave equation for wave motion of intermittent surges. We obtain mathematically the wave equation of shallow water with sediment on inclined channel which include intermittent debris flow. Using non-dimensional basic equation as Laplace equation, bottom boundary condition, surface condition (conservation condition of flow surface ), and equation of momentum. Using a method of perturbation, Gardner-Morikawa (G-M) transfer, we obtained wave equation of shallow water on inclined channel, and we solved the wave equation on periodical boundary and initial conditions of rectangle and sin function. depth direction y axis, Laplace equation is valid as follow, ∂ ∂ + ∂ ∂ = 2 2 2 2 0 φ φ x y (1) Defining velocity component of y direction v, a boundary condition of bottom in the flow is v y y h h = ∂ ∂ = = − ( ) φ 0 0 0 , : mean depth (2) Variance of flow surface from mean depth is defined as η (x, t), conservation condition of fluid of flow surface is satisfied with following equation. v y t x x = ∂ ∂ = ∂ ∂ + ∂ ∂ ∂ ∂ φ η φ η (3) The equations of momentum and conservation equation of shallow water with on inclined channel which momentum correction factor is β = 1 follows, ∂ ∂ + ∂ ∂ + − ( ) ∂ ∂ = − ∂ ∂ − u t u u x u A A t g g h x f u R β β
The Relationship between Auditor Partner Tenure , Auditor Industry Specialisation , Firm Complexity and Audit Fee

This research aims to analyse the influence of audit partner tenure, auditor industry specialisation and company complexity to audit fees. This research uses the quantitative approach and secondary data to measure variables to be studied. This research data consists of financial reports and annual reports. The selection method of the sample is the purposive sampling method. The population in this research were nonfinancial companies listed on the Indonesia Stock Exchange (IDX) from 2015 until 2017 with 544 observations being used as samples. This research was investigated using multiple linear regression analysis with SPSS 23 software. The result of the t-test with α = 0.05 indicates that auditor industry specialisation and company complexity has an impact on audit fees, while audit partner tenure has no impact on audit fees.
Analysis of Attenuation Anisotropy in Multi-Azimuth VSP Data from the Clair Field

E040 Z-99 Analysis of attenuation anisotropy in multiazimuth VSP data from the Clair field Abstract 1 We present an analysis of P-wave attenuation anisotropy in multi-azimuth walkaway VSP data from the Clair field. We find that the data recorded in the fractured oil-saturated reservoir show a consistent azimuthal variation in attenuation. This pattern cannot be observed in data recorded above the reservoir. The measured azimuth of minimum attenuation is close to the strike of open fluid-filled fractures mapped from cores and borehole image logs. The results therefore suggest a link between the attenuation pattern and the orientation of open fractures
The phenolic compounds of olive oil: structure, biological activity and beneficial effects on human health

Abstract The Mediterranean diet is rich in vegetables, cereals, fruit, fish, milk, wine and olive oil and has salutary biological functions. Epidemiological studies have shown a lower incidence of atherosclerosis, cardiovascular diseases and certain kinds of cancer in the Mediterranean area. Olive oil is the main source of fat, and the Mediterranean diet's healthy effects can in particular be attributed not only to the high relationship between unsaturated and saturated fatty acids in olive oil but also to the antioxidant property of its phenolic compounds. The main phenolic compounds, hydroxytyrosol and oleuropein, which give extra-virgin olive oil its bitter, pungent taste, have powerful antioxidant activity both in vivo and in vitro. The present review focuses on recent works analysing the relationship between the structure of olive oil polyphenolic compounds and their antioxidant activity. These compounds' possible beneficial effects are due to their antioxidant activity, which is related to the development of atherosclerosis and cancer, and to anti-inflammatory and antimicrobial activity.
The Binding of Aflatoxin B₁ Modulates the Adhesion Properties of Lactobacillus casei KCTC 3260 to a HT29 Colon Cancer Cell Line

【The 14 lactic acid bacteria (LAB) have been evaluated to determine the binding capacity to HT29 cell and Aflatoxin $B_1$ ( $AFB_1$ ). The interaction of LAB to HT29 cells has been further investigated to identify the possibility of competing the binding sites with $AFB_1$ . Of 14 LAB strains, Lactobacillus casei KCTC 3260 demonstrated the higher adhesiveness to HT29 and $AFB_1$ with the rate of 19.6% and 46.3%, respectively. In competitive analysis for binding sites, the adhesion of L. casei KCTC 3260 to HT29 cells was reduced with 100 nmol $AFB_1$ by 31.2%. The protoplast of L. casei KCTC 3260 showed no binding capacity to HT29 cells with increment of $AFB_1$ concentration, indicating that cell wall components might serve as a critical factor for the binding. To discriminate the major component influencing on L. casei KCTC 3260 binding to HT29 cells and $AFB_1$ , four different pre-treatments (lipase, pronase E, sodium m-periodate, and urea) were employed. Of those, sodium m-periodate treatment caused the lower adhesion of L. casei KCTC 3260 to HT29 cells with the increment of $AFB_1$ concentration. These results indicated that carbohydrate moiety on the cell wall of L. casei KCTC 3260 might be the most critical component in binding to both HT29 cells and $AFB_1$ . 】
Nasal Carriage of Staphylococcus Aureus among Healthy Students in a Nigerian University

Background: Staphylococcus aureus (S. aureus) nasal carriage is potential source for their continuous spread as well as risk factor for subsequent infections. Studies on S. aureus nasal carriage are important in determining the epidemiology of staphylococcal infections and a guide to infection control and preventive measures. Aim of the study: The present study was conducted to investigate the carriage prevalence and antibiotic susceptibility of S. aureus among students studying Medical Laboratory Science at the University of Jos. Materials and methods: Two hundred and forty one (241) nasal swab specimens were obtained from Medical laboratory science students of the University of Jos. Swabs were plated on Mannitol salt agar (MSA), culture plates were incubated at 37C for 18-24hours. After incubation S. aureus isolates were identified by their characteristic yellowish colony on MSA. Standard inocula were prepared by adjusting density of saline suspension of S.aureus to 0.5 McFarland’s standard. Antibiotic sensitivity was performed on Mueller Hinton agar by disc diffusion method. Zone diameter was read according to Clinical and Laboratory Standards Institute (CLSI) interpretative break point (CLSI 2004). Results: This study has established an overall carriage prevalence of 37.3%. The carriage rate was more in female 51 (40.4%) than male students 39 (33.9%). Regarding year of study 300level students 53 (46.4%) recorded the highest carriage rate while the least was noted among 500 level 8 (21.6%). Antibiotic susceptibility testing was performed using eight (8) antibiotics disc, all the isolates tested (n=90) were susceptible to vancomycin 90 (100.0%). Conclusion: There is high prevalence of S. aureus nasal carriage among Medical Laboratory Students at University of Jos. We recommend that studies on other potential sources like health care workers, medicine students, nursing students etc. be carried out in our setting.
DENSITY SCALING AND ANISOTROPY IN SUPERSONIC MHD TURBULENCE

We study the statistics of density for supersonic turbulence in a medium with magnetic pressure larger than the gaseous pressure. This study is motivated by molecular cloud research. Our simulations exhibit clumpy density structures, which contrast increases with the Mach number. At 10 Machs densities of some clumps are three orders of magnitude higher than the mean density. These clumps give rise to flat and approximately isotropic density spectrum corresponding to the random distribution of clumps in space. We claim that the clumps originate from our random, isotropic turbulence driving. When the contribution from those clumps is suppressed by studying logarithm of density, the density statistics exhibit scale-dependent anisotropy consistent with the models where density structures arise ⊥ ).
Prevalence, correlates, and experiences of school bullying among adolescents: A national study in Jordan

School bullying is recognized as a global problem and sparks public concerns for students’ safety. While it has recently emerged as a critical concern in the Arab world, particularly in Jordan, no national studies have yet investigated the extent of bullying in Jordanian schools. The purpose of this study was to investigate the prevalence, correlates, and experiences of bullying among a national sample of Jordanian adolescent students. A stratified random sampling procedure was used to select schools that represent the three main regions of Jordan (i.e. north, middle, and south) and a weighted sample of schools was randomly selected using Statistical Analysis System 9.4 based on provinces’ density. A nationally representative sample of 1083 adolescents aged 12 to 17 was included in the study. Data were collected using self-administered questionnaires on school bullying and adolescent sociodemographics. The prevalence of bullying among Jordanian adolescents was consistent with international studies; 7% reported their involvement in bullying as a victim, 7.6% as a bully, and 1.7% as both. Verbal bullying was the most common form of bullying among victims and bully-victim, while relational bullying was the most prevalent bullying for bullies. Being a perpetrator was more prevalent among boys than girls. Adolescent students who came from low socioeconomic status or whose fathers were illiterate reported more victimization experience. The majority of students who experienced bullying reported negative attitudes of bystanders, parents, and teachers towards intervening or responding to the bullying experience. Bullying exists among Jordanian students and active steps towards addressing this phenomenon are discussed. This is the first known Jordanian study representing a national sample of adolescent students’ experience of bullying. Findings present valuable information for school professionals, parents, and students regarding bullying and its associated factors. These findings also provide an avenue for the adoption and implementation of available anti-bullying programs to ameliorate bullying behaviors among Jordanian school students.
Smart covalent organic networks (CONs) with “on-off-on” light-switchable pores for molecular separation

2D membrane with azobenzene switches has the photo-responsive pores for nanofiltration. Development of the new-generation membranes for tunable molecular separation requires materials with abilities beyond strict separation. Stimuli response could remotely adjust the membrane selectivity. Azobenzene derivatives can be photo-switched between trans and cis isomers under ultraviolet or visible light. Here, the azobenzenes were implanted as light switches to bridge the flexible cyclen building blocks. The smart covalent organic network membranes fold and unfold as origami that can be photo-switched between on-state (large) and off-state (small) pores. The cis membranes with off state under ultraviolet (UV) light have higher dye rejection than trans membranes with on-state channels. By controlling the trans-to-cis azobenzene isomerization via UV/Vis light, the pore size can be remotely controlled at the molecular level and the solvent permeance and dye rejection can be dynamically tuned.
Caring for elderly parents: Perceived filial obligations among Maghrebine immigrants in Italy

The migrant population in Southern European countries is aging. In the next future, long-term care needs of immigrant individuals will be a major issue in the evolution of social policies in these countries. In this context, it becomes important to examine what are the norms of filial obligations that govern the exchange of social support within migrant families. The study focuses on solidarity norms and support expectations among Mahgrebine immigrants living in Italy. It is shown that: i. intergenerational co-residence is seen as the best strategy to cope with the care need of elderly parents; ii. only a minority of respondents, especially those born in Italy or arrived before age 6, think that providing economic support or hiring a professional carer is a good solution. The importance of cultural and religious motivations at the basis of norms of filial obligations was explicitly, particularly as far as cohabitation is concerned. The majority of respondents held a gender-neutral view with respect to the sharing of responsibilities, although some gendered divisions emerged. Respondents who either were born in Italy or migrated before age six are considerably more likely to hold gender-neutral views on the division of informal care work.
Single Nucleotide Polymorphism in KIR2DL1 Is Associated With HLA-C Expression in Global Populations

Regulation of NK cell activity is mediated through killer-cell immunoglobulin-like receptors (KIR) ability to recognize human leukocyte antigen (HLA) class I molecules as ligands. Interaction of KIR and HLA is implicated in viral infections, autoimmunity, and reproduction and there is growing evidence of the coevolution of these two independently segregating gene families. By leveraging KIR and HLA-C data from 1000 Genomes consortium we observed that the KIR2DL1 variant rs2304224*T is associated with lower expression of HLA-C in individuals carrying the ligand HLA-C2 (p = 0.0059). Using flow cytometry, we demonstrated that this variant is also associated with higher expression of KIR2DL1 on the NK cell surface (p = 0.0002). Next, we applied next generation sequencing to analyze KIR2DL1 sequence variation in 109 Euro and 75 Japanese descendants. Analyzing the extended haplotype homozygosity, we show signals of positive selection for rs4806553*G and rs687000*G, which are in linkage disequilibrium with rs2304224*T. Our results suggest that lower expression of HLA-C2 ligands might be compensated for higher expression of the receptor KIR2DL1 and bring new insights into the coevolution of KIR and HLA.
Growth Hormone and Insulin-like Growth Factor-I Molecular Weight Isoform Responses to Resistance Exercise Are Sex-Dependent

Purpose: To determine if acute resistance exercise-induced increases in growth hormone (GH) and insulin-like growth factor-I (IGF-I) were differentially responsive for one or more molecular weight (MW) isoforms and if these responses were sex-dependent. Methods: College-aged men (n = 10) and women (n = 10) performed an acute resistance exercise test (ARET; 6 sets, 10 repetition maximum (10-RM) squat, 2-min inter-set rest). Serum aliquots from blood drawn Pre-, Mid-, and Post-ARET (0, +15, and +30-min post) were processed using High Performance Liquid Chromatography (HPLC) fractionation and pooled into 3 MW fractions (Fr.A: >60; Fr.B: 30–60; Fr.C: <30 kDa). Results: We observed a hierarchy of serum protein collected among GH fractions across all time points independent of sex (Fr.C > Fr.A > Fr.B, p ≤ 0.03). Sex × time interactions indicated that women experienced earlier and augmented increases in all serum GH MW isoform fraction pools (p < 0.05); however, men demonstrated delayed and sustained GH elevations (p < 0.01) in all fractions through +30-min of recovery. Similarly, we observed a sex-independent hierarchy among IGF-I MW fraction pools (Fr.A > Fr.B > Fr.C, p ≤ 0.01). Furthermore, we observed increases in IGF-I Fr. A (ternary complexes) in men only (p ≤ 0.05), and increases in Fr.C (free/unbound IGF-I) in women only (p ≤ 0.05) vs. baseline, respectively. Conclusions: These data indicate that the processing of GH and IGF-I isoforms from the somatotrophs and hepatocytes are differential in their response to strenuous resistance exercise and reflect both temporal and sex-related differences.
Petrogenesis of the Late Oligocene Takht batholith, Southeastern Iran: Implications for the Diachronous Nature of the Arabia–Eurasia Collision

Zircon U-Pb age, mineral compositional, elemental and Sr-Nd isotopic data are documented for intermediate to felsic rocks in the Takht batholith, a Late Oligocene igneous complex in the southeastern segment of the Urumieh-Dokhtar belt, Iran, to investigate magma genesis in the context of regional tectonics. A large part of the magmatic belt formed by northward subduction of the Neotethys before the Arabia–Eurasia continental collision. Zircon U-Pb age data indicate the batholith crystallized at ∼25 Ma, an age consistent with previous results. Geochemical data indicate that the rocks share features typical of calc-alkaline magmas and I-type granitoids. The least evolved magma inferred from the data has basaltic andesite composition, consistent with either of the following origins: (i) a partial melt of the mantle followed by differentiation, or (ii) a partial melt of the lower crust. With increasing SiO2, (87Sr/86Sr)25Ma increases from 0.7053 to 0.7073, and εNd25Ma decreases from −0.3 to −2.9, consistent with increasing effects of assimilation–fractional crystallization, although processes such as magma mixing and melting of heterogeneous source rocks cannot be entirely ruled out. Aluminum-in-hornblende thermometry indicates that the batholith might have emplaced at ∼6.5 km or shallower paleo-depths. Moho depth proxies Sr/Y and (La/Yb)N yield crustal thickness of ∼20–30 km, showing no evidence for magma processing within thick crust. Overall, our results indicate that the Takht batholith is a Cordilleran-type batholith formed beneath a continental or transitional arc of normal crustal thickness. This is consistent with the notion that Arabia and Eurasia have collided in a diachronous manner, propagating from the northwest to the southeast since the Late Eocene–Early Oligocene.
Management Issues in Myasthenia Gravis Patients Living With HIV: A Case Series and Literature Review

South Africa is home to more than seven million people living with human immunodeficiency virus (HIV) and a high prevalence of tuberculosis. Human immunodeficiency virus–infected individuals may develop myasthenia gravis (MG), which raises questions regarding their management. An MG database, with 24 years of observational data, was audited for HIV-infected persons. Case reports of MG in HIV-infected persons were reviewed. We identified 17 persons with MG and HIV infection. All had generalized MG with a mean age at onset of 37.8 years. Eleven had acetylcholine receptor antibody–positive MG; one had antibodies against muscle-specific kinase. Six developed MG prior to HIV infection (mean CD4+ 361 cells/mm3); four worsened <6 months of starting antiretrovirals. Eleven developed MG while HIV-infected (mean CD4+ 423 cells/mm3); five presented with mild MG; three in MG crisis requiring rescue therapies (intravenous immune globulin or plasma exchange and/or intravenous cyclophosphamide). Two were diagnosed with HIV infection and MG at the same time. Fifteen required maintenance steroid-sparing immune therapies, predominantly azathioprine, or methotrexate. Plasma HIV viral loads remained below detectable levels on antiretrovirals during immunosuppressant treatment. Over the average follow-up of 6 years, 10 achieved minimal manifestation status, and the remainder improved to mild symptoms. Three cases had tuberculosis before MG, but none developed tuberculosis reactivation on immunosuppressive therapy; one used isoniazid prophylaxis. Herpes zoster reactivation during treatment occurred in one. Conclusions include the following: MG in HIV-infected patients should be managed similarly to individuals without HIV infection; half develop moderate–severe MG; MG symptoms may worsen within 6 months of antiretroviral initiation; safety monitoring must include plasma HIV viral load estimation. Isoniazid prophylaxis may not be indicated in all cases.
MicroRNA Expression Profiling of Bone Marrow–Derived Proangiogenic Cells (PACs) in a Mouse Model of Hindlimb Ischemia: Modulation by Classical Cardiovascular Risk Factors

Background Classical cardiovascular risk factors (CRFs) are associated with impaired angiogenic activities of bone marrow–derived proangiogenic cells (PACs) related to peripheral artery diseases (PADs) and ischemia-induced neovascularization. MicroRNAs (miRs) are key regulators of gene expression, and they are involved in the modulation of PAC function and PAC paracrine activity. However, the effects of CRFs on the modulation of miR expression in PACs are unknown. Aims and Methods We used a model of hindlimb ischemia and next-generation sequencing to perform a complete profiling of miRs in PACs isolated from the bone marrow of mice subjected to three models of CRFs: aging, smoking (SMK) and hypercholesterolemia (HC). Results Approximately 570 miRs were detected in PACs in the different CRF models. When excluding miRs with a very low expression level (<100 RPM), 40 to 61 miRs were found to be significantly modulated by aging, SMK, or HC. In each CRF condition, we identified downregulated proangiogenic miRs and upregulated antiangiogenic miRs that could contribute to explain PAC dysfunction. Interestingly, several miRs were similarly downregulated (e.g., miR-542-3p, miR-29) or upregulated (e.g., miR-501, miR-92a) in all CRF conditions. In silico approaches including Kyoto Encyclopedia of Genes and Genomes and cluster dendogram analyses identified predictive effects of these miRs on pathways having key roles in the modulation of angiogenesis and PAC function, including vascular endothelial growth factor signaling, extracellular matrix remodeling, PI3K/AKT/MAPK signaling, transforming growth factor beta (TGFb) pathway, p53, and cell cycle progression. Conclusion This study describes for the first time the effects of CRFs on the modulation of miR profile in PACs related to PAD and ischemia-induced neovascularization. We found that several angiogenesis-modulating miRs are similarly altered in different CRF conditions. Our findings constitute a solid framework for the identification of miRs that could be targeted in PACs in order to improve their angiogenic function and for the future development of novel therapies to improve neovascularization and reduce tissue damage in patients with severe PAD.