Miracle-dz/UniFAR-FTUs huggingface dataset:
Adverse events among medical patients after discharge from hospital.

BACKGROUND Adverse events (AEs) are adverse outcomes caused by medical care. Several studies have indicated that a substantial number of patients experience AEs before or during hospitalization. However, few data describe AEs after hospital discharge. We determined the incidence, severity, preventability and ameliorability of AEs in patients discharged from the general internal medicine service of a Canadian hospital. METHODS At a multisite Canadian teaching hospital, we prospectively studied patients who were consecutively discharged home or to a seniors' residence from the general internal medicine service during a 14-week interval in 2002. We used telephone interview and chart review to identify outcomes after discharge. Two physicians independently reviewed each outcome to determine if the patient experienced an AE. The severity, preventability and ameliorability of all AEs were classified. RESULTS During the study period, outcomes were determined for 328 of the 361 eligible patients, who averaged 71 years of age (interquartile range 54-81 years). After discharge, 76 of the 328 patients experienced at least 1 AE (overall incidence 23%, 95% confidence interval [CI] 19%-28%). The AE severity ranged from symptoms only (68% of the AEs) or symptoms associated with a nonpermanent disability (25%) to permanent disability (3%) or death (3%). The most common AEs were adverse drug events (72%), therapeutic errors (16%) and nosocomial infections (11%). Of the 76 patients, 38 had an AE that was either preventable or ameliorable (overall incidence 12%, 95% CI 9%-16%). INTERPRETATION Approximately one-quarter of patients in our study had an AE after hospital discharge, and half of the AEs were preventable or ameliorable.
Framework and estimation of ear biometrics detection for digital forensic applications

Currently, forensic electronics and computers become an attractive scientific and engineering application area. They are applied to determine and identify accused or evidences used in court. However, the determination, verification and identification processes have been manually executed by experts, where they take time to come out conclusions and results. With rapidly increment of illegal cases, reducing the processing time or verifying step to identify possible suspects is significantly importance to increase efficiency. This paper first introduces a framework to identify possible suspects purpose to primary screening in forensic application. The identification of human ears in several degrees based on edge detection techniques is second considered. With the edge detection techniques corresponding to their suitable input parameters, our experimental results, with a 0.3 threshold and a 0.75 factor k, have reported that the human's ear identities can be detected and extracted.
E-PLE: an Algorithm for Image Inpainting

Gaussian mixture is a powerful tool for modeling the patch prior. In this work, a probabilistic view of an existing algorithm piecewise linear estimation (PLE) for image inpainting is presented which leads to several theoretical and numerical improvements based on an eective use of Gaussian mixture. Source Code An ANSI C++ implementation of the algorithm has been peer reviewed and is accessible at the IPOL web page of this article 1 .
Comparative performance study of space priority mechanisms for ATM networks

Priorities for buffer access, also called space priorities, are discussed in connection with the asynchronous transfer mode (ATM), which is widely accepted as the basis for the future broadband ISDN. The introduction of priorities enables the ATM layer to adapt the quality of the cell transfer to the quality of service requirements of the specific broadband ISDN services in order to improve the utilization of the network resources. A description is given of different space priority mechanisms and their performance evaluation. A comparative performance study of these concepts is given, indicating the good performance characteristics of a simple buffering scheme called partial buffer sharing. <<ETX>>
Frequency and etiology of hand and forearm dermatoses among veterinarians.

BACKGROUND Veterinarians are exposed to a range of skin irritants and allergens, yet few studies have addressed the occurrence of dermatoses among veterinarians. OBJECTIVES The goals of this study were to determine the frequency of noninfectious hand and forearm dermatoses among Kansas veterinarians, to estimate the role of occupational exposures in the aggravation of such dermatoses, to determine the frequency and nature of infectious dermatoses among veterinarians, and to investigate patterns of glove use. The secondary goals of this study were to collect information about the impact of skin disease on the lives and careers of veterinarians and to provide physicians with a practical approach to the treatment of veterinarians with dermatoses. METHODS A questionnaire was mailed to all members of the Kansas Veterinary Medical Association. RESULTS The response rate was 60%. Twenty-four of respondents reported noninfectious, recurrent/persistent hand or forearm dermatoses; 66% were work related. Large animal veterinarians (P =.026) and atopics (P =.009) were more likely than their counterparts to attribute their dermatoses to work-related factors. Thirty-eight percent of respondents had contracted at least one infectious skin disease from an animal. Veterinarians who never or rarely use gloves during obstetric procedures were more likely to report work-related dermatoses (odds ratio, 4.25; 1.78 < OR < 10.07; P <.001) than those who use gloves. CONCLUSION Veterinarians are affected frequently by infectious and noninfectious dermatoses. Improvement of barrier protection habits during obstetric procedures would likely reduce the frequency of occupational dermatoses among veterinarians.
Treatment of carcinoma of the parotid gland: the results of a multicenter study.

PURPOSE This study analyzed the prognostic factors for carcinoma of the parotid gland and the role of surgery alone or with radiotherapy in treating these lesions. METHODS Forty-five patients with malignant parotid tumors were studied retrospectively. Patients were treated by combined surgery and radiation therapy between 1984 and 1995 at the Maxillo-Facial Departments of the General Hospitals of Bologna and Parma. Resection was conservative when possible, depending on the extent of the tumor. The median follow-up time was 54 months. Data regarding incidence, tumor stage and grade, local control, distant metastases (calculated with the Kaplan-Meier method), and survival were analyzed. Cox's multiple linear regression was used to identify patient and tumor characteristics with the greatest prognostic significance. RESULTS The actuarial 5- and 8-year disease-free survival rates were 81% and 62%, respectively. Multivariate analysis showed that tumor stage was a more prognostic variable than tumor grade. Residual microscopic disease at the excision margins was also an important prognostic variable. Laterocervical metastases affected 4 patients (9%), and distant metastases appeared in 8 patients (18%). CONCLUSIONS Postoperative irradiation is indicated for patients with stage III and IV disease, patients with positive excision margins, and for patients with lymph node metastases.
An online interprofessional learning resource for physicians, pharmacists, nurse practitioners, and nurses in long-term care: Benefits, barriers, and lessons learned

The importance of collaborative practice in health care has been emphasized. There is a critical need for convenient and flexible education opportunities that support the development of collaborative practice skills among the health care workforce. Consequently, the purpose of this project was to create and evaluate an online learning resource for physicians, nurses, nurse practitioners, and pharmacists working in long-term care that provided practitioners with the skills, knowledge, and motivation necessary to enhance their ability to act as an interprofessional team while providing clinical care. The Demand-Driven Learning Model was used to guide the project. Findings revealed learners enjoyed the programme and acquired new skills and knowledge relating to collaborative practice that they transferred to their workplace resulting in higher levels of collaborative practice. The data did not reveal significant changes in the learners' attitudes towards collaborative practice; perhaps because the participants were early adopters and already had positive attitudes. Requests to change organizational structure to enhance collaborative practice were minimal, as was the impact of the resource on resident care. Given the short time frame from completion of the learning resource to the evaluation, this is perhaps not surprising as it is reasonable to expect that these types of changes will take time to take effect within the organization. Follow-ups at a later date are suggested.
Redes sociales y motores de búsqueda

Internet puede verse desde hace algunos anos como un flujo constante de informacion. Esto se debe en gran parte al contenido producido en las redes sociales. Dicha cuestion puede apreciarse, por ejemplo, en las plataformas de microblogging y dentro de ellas sobre todo en Twitter. Entre las caracteŕisticas mas importantes de esta plataforma se encuentran los Trending Topics, que son un listado de frases, terminos y etiquetas relacionados a los temas emergentes mas populares en la red social en determinado momento. Aśi, teniendo en cuenta las cuestiones previamente mencionadas, cabe preguntarse si el hecho de que cierto tema sea Trending Topic, influye de algun modo en el volumen de consultas que recibe un motor de busqueda sobre dicho tema. Este proyecto propone explorar y analizar dicha cuestion y su aplicacion en la mejora de los algoritmos de busqueda. Palabras clave: redes sociales, motores de busqueda, trending topics.
Mitochondrial Function and Maize Kernel Development Requires Dek2, a Pentatricopeptide Repeat Protein Involved in nad1 mRNA Splicing

In flowering plants, many respiration-related proteins are encoded by the mitochondrial genome and the splicing of mitochondrion-encoded messenger RNA (mRNA) involves a complex collaboration with nuclear-encoded proteins. Pentatricopeptide repeat (PPR) proteins have been implicated in these RNA–protein interactions. Maize defective kernel 2 (dek2) is a classic mutant with small kernels and delayed development. Through positional cloning and allelic confirmation, we found Dek2 encodes a novel P-type PPR protein that targets mitochondria. Mitochondrial transcript analysis indicated that dek2 mutation causes reduced splicing efficiency of mitochondrial nad1 intron 1. Mitochondrial complex analysis in dek2 immature kernels showed severe deficiency of complex I assembly. Dramatically up-regulated expression of alternative oxidases (AOXs), transcriptome data, and TEM analysis results revealed that proper splicing of nad1 is critical for mitochondrial functions and inner cristaes morphology. This study indicated that Dek2 is a new PPR protein that affects the splicing of mitochondrial nad1 intron 1 and is required for mitochondrial function and kernel development.
Bone Morphogenetic Proteins, Extracellular Matrix, and Mitogen‐Activated Protein Kinase Signaling Pathways Are Required for Osteoblast‐Specific Gene Expression and Differentiation in MC3T3‐E1 Cells

Osteoblasts secrete a complex extracellular matrix (ECM) containing collagenous and noncollagenous proteins, bone morphogenetic proteins (BMPs), and growth factors. Osteoblast‐specific gene expression requires ascorbic acid (AA)‐dependent assembly of a collagenous ECM. Matrix responsiveness requires an α2β1 integrin‐collagen interaction and mitogen‐activated protein kinase (MAPK) activity, which phosphorylates and activates the osteoblast‐specific transcription factor Cbfa1. This study examines interactions between this integrin/MAPK‐mediated pathway and signals initiated by BMPs contained in the osteoblast matrix. MC3T3‐E1 cells were shown to constitutively express BMP‐2, BMP‐4, and BMP‐7. Noggin, a specific BMP inhibitor, reversibly blocked AA‐induced gene expression, indicating that BMP production by MC3T3‐E1 cells was necessary for differentiation. The ability of exogenously added BMP‐2, BMP‐4, or BMP‐7 to stimulate osteocalcin (OCN) and bone sialoprotein (BSP) mRNAs or OCN promoter activity was synergistically increased in cells that were actively synthesizing an ECM (i.e., were grown in the presence of AA). A minimum of 4 days of ECM accumulation was required for this synergistic response to be observed. Neither BMP‐7, AA, nor a combination of these two treatments had major effects on Cbfa1 messenger RNA (mRNA) or protein levels, as would be expected if regulation was mainly at the posttranscriptional level. U0126, a specific inhibitor of MAPK/extracellular signal‐regulated kinase (MEK), blocked AA‐ or BMP‐7/AA‐dependent gene expression in a time‐ and dose‐dependent manner that was closely correlated with inhibition of extracellular signal‐regulated kinase (ERK) phosphorylation. This work establishes that autocrine BMP production as well as integrin‐mediated cell‐collagen interactions are both required for osteoblast differentiation, and both these pathways require MAP kinase activity.
Perceptions of Illness in Self and in Others Among Patients With Bipolar Disorder

Aim: The study aimed to examine the perceptions of illness in self and among others in patients with bipolar disorder in remission. The effect of a structured educational programme on the perceptions of illness was also tested. Method: We examined the perceptions of illness in self and in others (using a vignette) among patients with bipolar disorder in remission attending the Department of Psychiatry, Christian Medical College, Vellore, India. We also examined the effect of a structured educational programme on explanatory models in a randomized controlled trial. Explanatory models were assessed using the Tamil version of the Short Explanatory Model Interview. Results: Eighty two subjects were recruited for the trial; half of them received structured education while the other half received treatment as usual. There was agreement between perceptions related to the individual’s own illness and their opinion of illness in others as assessed using a vignette at baseline and at follow-up. There were no significant differences in explanatory models between patients who received education and those who did not. Conclusions: The results of this study show that during periods of remission, patients can clearly see the relationship between their own illness and that described in others, suggesting that insight is state dependent and may be related to psychopathology with good recovery of insight during periods of remission. These findings also argue for the fact that the current multi-dimensional models of insight which focus on biomedical explanations and treatments are not culturally sensitive. The assessment of insight demands universal conventions with comparison to the local cultural standards rather than universal defi nitions and yardsticks which employ Western and biomedical perspectives.
De ambtelijke beleidsvormingsrol verkend en getoetst in meervoudig vergelijkend perspectief : een two-level analyse van de rol van Vlaamse ambtenaren in de Vlaamse beleidsvorming.

Dit proefschrift handelde over de beleidsvormingsrol van ambtenaren. Een onderzoeksobject dat nog maar zelden grondig & theoretisch was bestudeerd. Het ‘klassieke’ rolonderzoek richtte zich vooral op verwachtingen en/of opvattingen over (gewenst) gedrag, waardoor feitelijk ambtelijk gedrag tot nog toe maar zelden het hoofdobject van een rolstudie vormde. Daar wilde ik met mijn doctoraatsonderzoek verandering in brengen. Mijn zoektocht naar de ambtelijke beleidsvormingsrol behelste dus een genuanceerde exploratie van het karakteristieke gedragsrepertoire van ambtenaren in het kader van de beleidsvorming. Met genuanceerd doel ik niet alleen op een analyse van concrete beleidstaken, maar ook op het bestuderen van de ambtelijke rol te midden van het volledige actorenveld waarbinnen beleid wordt uitgewerkt. Veel van het rolonderzoek over ambtenaren bleef immers beperkt tot het bestuderen van het werk/de opvattingen van ambtenaren in de politiek-ambtelijke ruimte. ^
Duodenal mucosal damage in 31 infants with gastroenteritis

Duodenal biopsies taken in the acute stage of gastroenteritis in 31 infants have shown histological abnormality and disaccharidase depression in the majority. In 5, mucosal damage was severe with changes similar to those seen in coeliac disease. Repeat biopsies in 3 of these showed marked improvement after 3 days, 8 days, and 7 weeks, respectively. Persisting sugar intolerance occurred in approximately 50% of patients under 6 months of age, but this complication bore no relation to disaccharidase depression in the acute stage of the illness.
Interactive Pixel‐Accurate Free Viewpoint Rendering from Images with Silhouette Aware Sampling

We present an integrated, fully GPU‐based processing pipeline to interactively render new views of arbitrary scenes from calibrated but otherwise unstructured input views. In a two‐step procedure, our method first generates for each input view a dense proxy of the scene using a new multi‐view stereo formulation. Each scene proxy consists of a structured cloud of feature aware particles which automatically have their image space footprints aligned to depth discontinuities of the scene geometry and hence effectively handle sharp object boundaries and occlusions. We propose a particle optimization routine combined with a special parameterization of the view space that enables an efficient proxy generation as well as robust and intuitive filter operators for noise and outlier removal. Moreover, our generic proxy generation allows us to flexibly handle scene complexities ranging from small objects up to complete outdoor scenes. The second phase of the algorithm combines these particle clouds in real‐time into a view‐dependent proxy for the desired output view and performs a pixel‐accurate accumulation of the colour contributions from each available input view. This makes it possible to reconstruct even fine‐scale view‐dependent illumination effects. We demonstrate how all these processing stages of the pipeline can be implemented entirely on the GPU with memory efficient, scalable data structures for maximum performance. This allows us to generate new output renderings of high visual quality from input images in real‐time.
Las preferencias de los bogotanos por las características socioeconómicas de sus vecinos ¿Modelan la estructura urbana?

En Bogota se observan patrones de concentracion en el espacio de viviendas con atributos fisicos similares y de hogares con caracteristicas socioeconomicas similares, pero hay poca informacion para entender como se llega a este resultado. No se conoce si este ordenamiento ocurre como consecuencia de efectos de correlacion (hogares similares tienen capacidad de pago y preferencias similares y, por lo tanto eligen viviendas similares) o efectos de contexto (los hogares valoran la composicion socioeconomica de los hogares que los rodean). Este documento responde si los efectos de contexto explican el equilibrio urbano. Para esto utiliza una tecnica de regresion discontinua que controla por las caracteristicas no observables de la vivienda y su entorno, en espacios donde existe discontinuidad en los precios y hay continuidad en los atributos fisicos de las viviendas. Esto permite controlar por los efectos de correlacion e identificar los de contexto. Utilizando datos geo-referenciados de la Encuesta Multipropositos de Bogota 2011 y el Censo de Catastro 2013 se encuentra que los efectos de contexto modelan la estructura urbana de Bogota: los hogares no valoran el nivel de gasto promedio de sus vecinos sino su nivel de educacion. Ademas, valoran estar en espacios con gastos promedio que se distancian del propio.
Genome Sequence of Oceanibaculum indicum Type Strain P24

ABSTRACT Oceanibaculum indicum type strain P24 was isolated from a polycyclic-aromatic-hydrocarbon-degrading consortium enriched from a deep-seawater sample collected from the Indian Ocean. Here we present the draft genome of strain P24T, which contains 3,952,792 bp with a G+C content of 65.5% and contains 3,755 protein-coding genes and 45 tRNAs.
Optimal Joint Routing and Scheduling in Millimeter-Wave Cellular Networks

Millimeter-wave (mmWave) communication is a promising technology to cope with the expected exponential increase in data traffic in 5G networks. mmWave networks typically require a very dense deployment of mmWave base stations (mmBS). To reduce cost and increase flexibility, wireless backhauling is needed to connect the mmBSs. The characteristics of mmWave communication, and specifically its high directionality, imply new requirements for efficient routing and scheduling paradigms. We propose an efficient scheduling method, so-called schedule-oriented optimization, based on matching theory that optimizes QoS metrics jointly with routing. It is capable of solving any scheduling problem that can be formulated as a linear program whose variables are link times and QoS metrics. As an example of the schedule-oriented optimization, we show the optimal solution of the maximum throughput fair scheduling (MTFS). Practically, the optimal scheduling can be obtained even for networks with over 200 mmBSs. To further increase the runtime performance, we propose an efficient edge-coloring based approximation algorithm with provable performance bound. It achieves over 80% of the optimal max-min throughput and runs 5 to 100 times faster than the optimal algorithm in practice. Finally, we extend the optimal and approximation algorithms for the cases of multi-RF-chain mmBSs and integrated backhaul and access networks.
The Distribution of Zinc Selenite and Expression of Metallothionein-III mRNA in the Spinal Cord and Dorsal Root Ganglia of the Rat Suggest a Role for Zinc in Sensory Transmission

Zinc appears to play a role in synaptic transmission in the hippocampus. We tested the hypothesis that zinc is similarly involved in sensory transmission by determining whether vesicular zinc and metallothionein-III (MT-III), a zinc-binding protein, are localized in rat primary afferent neurons. MT-III mRNA, measured using RT-PCR, and MT-III immunoreactivity, were both present in the spinal cord as well as the thoracic and lumbar dorsal root ganglia (DRG). At a time (24 hr) that allows retrograde transport of zinc selenite to cell bodies, only small-diameter neurons and neurons scattered throughout lamina V of the spinal cord were stained by sodium selenite injected intrathecally. This stain disappeared if a ligature was placed on the dorsal root to block axonal transport, demonstrating that these cells are, in fact, zinc-containing primary afferent neurons. When assessed 1 hr after sodium selenite, stain was distributed throughout the neuropil of the spinal cord, especially in lamina III and the area surrounding the central canal. Even in rhizotomized animals, large- and small-diameter DRG neuronal cell bodies were also stained with either selenite (1 hr) or 6-methoxy 8-para-toluene sulfonamide quinoline (TSQ). Paradoxically, this unique pool of zinc was eliminated in large-diameter DRG neurons after neonatal capsaicin treatment, which had no effect on selenite stain or MT-III mRNA content in small-diameter DRG neurons. In summary, we demonstrate that there is a population of capsaicin-insensitive small-diameter primary afferent neurons that are zinc-containing. In addition, there is a unique pool of capsaicin-sensitive zinc that is associated with large-diameter cell bodies.