Miracle-dz/UniFAR-FTUs huggingface dataset:
Manifestations of Proprioception During Vertical Jumps to Specific Heights

Abstract Artur, S, Bogdan, P, Kawczyński, A, Winiarski, S, Grzegorz, J, and Andrzej, R. Manifestations of proprioception during vertical jumps to specific heights. J Strength Cond Res 31(6): 1694–1701, 2017—Jumping and proprioception are important abilities in many sports. The efficiency of the proprioceptive system is indirectly related to jumps performed at specified heights. Therefore, this study recorded the ability of young athletes who play team sports to jump to a specific height compared with their maximum ability. A total of 154 male (age: 14.8 ± 0.9 years, body height: 181.8 ± 8.9 cm, body weight: 69.8 ± 11.8 kg, training experience: 3.8 ± 1.7 years) and 151 female (age: 14.1 ± 0.8 years, body height: 170.5 ± 6.5 cm, body weight: 60.3 ± 9.4 kg, training experience: 3.7 ± 1.4 years) team games players were recruited for this study. Each participant performed 2 countermovement jumps with arm swing to 25, 50, 75, and 100% of the maximum height. Measurements were performed using a force plate. Jump height and its accuracy with respect to a specified height were calculated. The results revealed no significant differences in jump height and its accuracy to the specified heights between the groups (stratified by age, sex, and sport). Individuals with a higher jumping accuracy also exhibited greater maximum jump heights. Jumps to 25% of the maximum height were approximately 2 times higher than the target height. The decreased jump accuracy to a specific height when attempting to jump to lower heights should be reduced with training, particularly among athletes who play team sports. These findings provide useful information regarding the proprioceptive system for team sport coaches and may shape guidelines for training routines by working with submaximal loads.
The distribution of aerosol optical depth retrieved by TM imagery over Beijing urban area, China

Particulate matter (PM) air-quality information is usually derived from ground based instruments. These measurements, while valuable, are not well suited to provide air-quality information over large spatial scales. In this paper, the extended dense dark vegetation algorithm is selected to retrieval the aerosol optical thickness using 6S radioactive transfer model based on Landsat TM data over the Beijing city in non-heating season. The results shows that the distribution of trend expansion from the maps, there is two high-value areas of aerosol optical thickness which are located in Haidian and Fengtai district, Xicheng district will also appear high-value areas in some cases. The urban scale PM10 distribution matches the AOD distribution retrieved by TM imagery quite well.
INHIBITION OF NEUTROPHIL MIGRATION AT THE SITE OF INFECTION INCREASES REMOTE ORGAN NEUTROPHIL SEQUESTRATION AND INJURY

Up-regulation of the leukocyte β2 integrin, CD18, is a key event in neutrophil-endothelial adhesion and neutrophil-mediated organ injury. Inhibition of CD18 with monoclonal antibodies reduces lung and liver neutrophil sequestration in animal models of Gram-negative bacteremia or endotoxemia. However, with a persistent septic challenge, interference with host leukocyte phagocytic defense could adversely affect outcome. To assess the effects of inhibiting CD18 on organ neutrophil responses, bacteremia, and organ injury after fecal peritonitis, mice underwent cecal ligation and puncture (CLP). At the time of CLP and 12 h later, mice received intravenous anti-CD18 antibody or control IgG. At 3, 6, and 18 h after CLP, lung and liver tissue neutrophil content were measured by myeloperoxidase (MPO) assay, peritoneal cells and blood leukocytes were differentially counted, blood was cultured, and serum aspartate aminotransferase was measured. There was a significant reduction in peritoneal neutrophil migration and an increase in blood neutrophils after anti-CD18 treatment compared with results from treatment with the control antibody. In the anti-CD18-treated group, liver MPO was increased fivefold at 6 and 18 h, while lung MPO was increased two-fold at 18 h when compared with the control antibody-treated group. The anti-CD18-treated group also had an increase in bacteria cultured from the blood at 6 and 18 h and an increase in serum aminotransferase at 18 h. Our data demonstrate that peritoneal neutrophil migration in response to an endogenous fecal challenge is CD18-dependent, and that this mechanism forms a vital part of host defense. Inhibition of CD18 increased neutrophil sequestration in the liver and lung and increased liver injury. This study demonstrates a paradoxical increase in organ neutrophil sequestration using a leukocyte anti-adhesion therapy during sepsis and suggests that anti-adhesion therapies targeted towards neutrophil may worsen outcome if given during an ongoing, localized infection.
Built-in self-test and repair (BISTR) techniques for embedded RAMs

High-density and high capacity embedded memories are important components for successful implementation of a system-on-a-chip. Since embedded memory cores usually occupy a large portion of the chip area, they will dominate the manufacturing yield of the system chips. In this paper, a built-in self-test and repair (BISTR) approach is proposed for semiconductor memories with 1-D redundancy (redundant rows) structures. The memory rows are virtually divided into row blocks and reconfiguration is performed at the row block level instead of the traditional row level. That is, the virtual divided word line (VDWL) concept is used for repairing of memory cores. The hardware overhead is almost negligible. An experimental chip is implemented and shows a low area overhead - about 3.06% for a 256 /spl times/ 512 SRAM with 4 spare rows. We also compare the repair rate of our approach with previous memory repair algorithms. It also concludes that our approach improves the repair rate significantly.
Use of the Sensititre Colorimetric Microdilution Panel for Antifungal Susceptibility Testing of Dermatophytes

ABSTRACT The Sensititre YeastOne antifungal panel was used to test 49 dermatophytes belonging to the species Epidermophyton floccosum, Microsporum gypseum, Microsporum canis, Trichophyton tonsurans, Trichophyton rubrum, and Trichophyton mentagrophytes. The MICs of four antifungals obtained with the Sensititre YeastOne antifungal panel were compared with those obtained by the reference NCCLS microdilution method. The levels of agreement between the two methods (≤2 dilutions) were 81.6% with amphotericin B, 87.7% with itraconazole, 67.3% with fluconazole, and 69.4% with ketoconazole.
Colon cancer screening in 2005: status and challenges.

The field of colon cancer screening has evolved dramatically in the last 15 years regarding evidence, guidelines, and practice. In 1990, no evidence from a randomized controlled clinical trial (RCT) existed to show that colorectal cancer (CRC) screening was effective in reducing CRC mortality. In 1990, although some guidelines endorsed screening, there was disagreement among recommending organizations about which tests to recommend or whether to recommend any screening tests at all. The US Preventive Services Task Force (USPSTF), arguably the most influential of the recommending organizations and the most rigorously evidence based, said that evidence was insufficient to recommend either for or against CRC screening.1 In this environment, CRC screening was not widely practiced, much less reimbursed by payers. If screening was performed at all, fecal occult blood testing (FOBT) was the most common test. Sigmoidoscopy was performed less frequently, and colonoscopy, rarely performed for screening, was used mainly for workup of a positive FOBT or sigmoidoscopy and for postpolypectomy surveillance. The primary questions facing academics, recommending organizations, and practicing clinicians in 1990 were (1) does CRC screening—of any kind—work to reduce CRC mortality, and (2) should it be implemented and reimbursed? In 2005, the situation is dramatically different. We now know that CRC screening works, and it is now being implemented and reimbursed. Colonoscopy has become popular as a primary screening test, and new tests, such as virtual colonoscopy, are being developed. The purpose of this article is to identify current challenges in light of the evolution of evidence, guidelines, and practice and to anticipate the next phase of development and implementation.
Elevated Fibroblast Growth Factor 23 Concentration: Prediction of Mortality among Chronic Kidney Disease Patients

Background: The osteocyte-derived hormone, fibroblast growth factor 23 (FGF23), regulates the phosphorus metabolism and suppresses 1,25-dihydroxyvitamin D production, thereby mitigating hyperphosphatemia in patients with renal disorders. An elevated FGF23 level is suggested to be an early biomarker of altered phosphorus metabolism in the initial stages of chronic kidney disease (CKD) and acts as a strong predictor of mortality in dialysis patients. In the Saudi population, there is no report on the FGF23 level in CKD patients to date. This study aims to estimate the plasma FGF23 levels in the Saudi population and to correlate it with its clinical manifestations in order to ascertain its role in the pathogenesis of CKD patients. Methods: The FGF23 level in the plasma samples was determined using ELISA in a diverse cohort of 89 cases with stage 3-5 CKD and 100 healthy subjects. The plasma FGF23 level was correlated with other biochemical parameters. Results: The results revealed that the FGF23 level was markedly elevated among CKD patients compared to the control group, and a significant inverse correlation was observed between the FGF23 level and glomerular filtration rate. FGF23 elevation was approximately 40-fold among stage 5 patients compared to the control, while the elevation of phosphate, parathyroid hormone (PTH) and alkaline phosphatase was 2-, 3- and 8-fold in this stage, respectively. Conclusion: Elevated FGF23 levels may have a strong correlation with the disease pathogenesis. In addition, FGF23 might be a future therapeutic target to intervene against the progression of CKD as well as to increase patient survivability.
RNA Analysis by Nuclease Protection

Nuclease protection assays (S1 nuclease protection and RNase protection) are extremely sensitive procedures for detection and quantitation of mRNA species in complex mixtures of total cellular RNA. These assays are well suited for mapping positions of external and internal junctions in RNA, such as transcription initiation and termination sites and intron/exon boundaries, and to discriminate between closely related targets by using probes designed to span the regions where the related genes differ the most. Also, because the size of the probes used in nuclease protection assays is a variable chosen by the investigator, probes may be designed to protect fragments of different sizes. This feature permits the simultaneous analysis of several different mRNAs in the same total RNA sample. In this unit, a method is included for RNase protection of target mRNA sequences, including hybridization of the probe to the target sequence, details of the actual protection assay, and detection of reaction products. An alternative method is provided for performing the RNase protection assay on a microvolume scale, which is useful when there are many samples to be analyzed. Support protocols describe synthesis and gel purification of labeled RNA probes; preparation of RNase‐free yeast RNA, which acts as an aid in the quantitative precipitation of newly synthesized probe; and quantitation of target mRNA. A method describing S1 nuclease protection of target mRNA using either RNA or DNA probes is also included. Additional support protocols provide instructions for the preparation of radiolabeled DNA probes by primer‐extension of double‐stranded plasmid or PCR product using Klenow fragment of E. coli DNA polymerase I or Taq or Tth polymerase in a thermal cycler. Another radiolabeling method details 5' end labeling of oligodeoxynucleotides and oligoribonucleotides using T4 polynucleotide kinase. Additionally, a method is described for mapping transcription start sites using the S1 nuclease protection assay.
Race, socioeconomic status, and rurality influences on type 2 diabetes management among North Carolina adults.

PURPOSE To examine the impact of race, socioeconomic status, and rurality on Type 2 diabetes education among adults in North Carolina. METHODS Our study utilized data from the 2008 Behavioral Risk Factor Surveillance System (BRFSS) to conduct a retrospective study and secondary data analysis. To account for the multistage survey design of BRFSS, SAS/SUDAAN was used to calculate adjusted and unadjusted odds ratios and 95% confidence intervals (CIs). Univariate, bivariate, and multivariate analyses were performed to examine the association between race, socioeconomic status, and rurality and its effects on type 2 diabetes education among adults in North Carolina. MAIN FINDINGS The majority of the participants (63%) did not have good diabetes education. Non-Whites had higher odds than Whites of good diabetes education (OR=1.56, 95%CI: 1.19, 2.03). Individuals who lived in rural North Carolina had lower odds of having good diabetes education than their urban counterparts, but the results remained insignificant (OR=.88, CI: .67, 1.15). Individuals who were of low socioeconomic status (SES) had poorer diabetes education than individuals who were identified as being high SES, but the results were insignificant (OR=.81, CI: .60, 1.09). PRINCIPAL CONCLUSIONS Findings from the study indicate that non-White adults had higher odds than Whites of good type 2 diabetes education in North Carolina. The results of our study could be used for policies and recommendations for health organizations. Policy makers should make diabetes education mandatory for individuals who are diagnosed with this disease. Future studies should have a more accurate measurement of type 2 diabetes education.
Patient, wound, and treatment characteristics associated with healing in pressure ulcers.

OBJECTIVE To examine the associations among selected patient, wound, and treatment factors and healing in pressure ulcers. DESIGN Nonexperimental, retrospective study using data extracted from charts of patients having a Stage II, III, or IV pressure ulcer between July 1994 and November 1996. SETTING A long-term-care facility associated with a major metropolitan medical center. RESULTS Evidence of healing was significantly associated with patient weight (P < .05) and negatively associated with body temperature (P < .05), time on a pressure-relieving bed (P < .05), amount of exudate (P < .001), and stage of pressure ulcer (P < .001). In a regression analysis, pressure ulcer stage, patient weight, and mean body temperature explained 25% of the variability in healing; specifically, lower pressure ulcer stage, higher patient weight, and lower mean body temperature predicted improved healing. Healing was not predicted by chronologic age, pressure ulcer location, number of illnesses, use of tube feedings, use of pressure-relieving beds, mean arterial pressure, or Braden Scale score. In a regression analysis of patient factors alone, lower body temperature and higher weight together predicted 9% of the variance in healing. When wound variables were analyzed, 19% of the variability in healing was explained by the stage of the pressure ulcer. Of the treatment variables, only shorter time on a pressure-relieving bed predicted healing, explaining 6% of the variance. CONCLUSIONS Strategies for healing pressure ulcers in nursing home patients should include programs for early recognition of pressure injury and prevention of pressure ulcer progression to higher stages; attention to weight gain and/or weight maintenance in at-risk patients; and early recognition and treatment of infections and febrile episodes.
Nonlinear time-varying system identification with recursive Gaussian process

Gaussian process model provides a flexible, probabilistic, non-parametric model. Many examples for system identification using Gaussian process have been reported and verified. However, for real plants that have secular change or whose properties change upon time, it is difficult to apply standard Gaussian process and it is important to keep the uncertainties of the modeling properly. In this paper, we consider a system identification for nonlinear time-varying systems using recursive Gaussian process (RGP). We propose two methods for this problem. One is RGP for long-term prediction, and the another is robust RGP for outliers. The effectiveness of the proposed methods will be shown by numerical simulations.
THE APPLICATION OF ANTICIPATORY AVOIDANCE LEARNING TO THE TREATMENT OF HOMOSEXUALITY

The authors have been carrying out a programme of research into the aversion therapy treatment of homosexuality by anticipatory avoidance learning over the past five years. Previous papers have described the rationale and technique of the treatment method used (Feldman & MacCulloch (1964 and 1965) ; MacCulloch & Feldman (1967 a) ), methods of recording response latencies and pulse rate changes (MacCulloch, Feldman & Pinschof (1965) ), a questionnaire technique for assessing changes in sexual orientation (Feldman, MacCulloch, Mellor & Pinschof (1966) ), and the relationship between personality and the outcome of treatment (MacCulloch & Feldman ( 1967 a) ) . The technique has been applied to cases of sexual deviation other than homosexuality (Feldman, MacCulloch & MacCulloch ( 1968) ). Finally, we have published data on the treatment and follow-up of an unselected series of 43 homosexual patients (MacCulloch & Feldman (1967 b) ). Several shortcomings of technique, control and recording have emerged during the course of our research programme, and further developments designed to deal with these have taken place since the series of 43 patients was closed. These developments, in addition to being desirable in themselves, were also necessary as essential preliminaries to carrying out a controlled trial of anticipatory avoidance learning in the treatment of homosexuality. The analysis of this trial is now taking place and the results will be reported shortly.
Susceptibility of isolated myofibrils to in vitro glutathionylation: Potential relevance to muscle functions

In this study we investigated the molecular mechanism of glutathionylation on isolated human cardiac myofibrils using several pro‐glutathionylating agents. Total glutathionylated proteins appeared significantly enhanced with all the pro‐oxidants used. The increase was completely reversed by the addition of a reducing agent, demonstrating that glutathione binding occurs by a disulfide and that the process is reversible. A sensitive target of glutathionylation was α‐actin, showing a different reactivity to the several pro‐glutathionylating agents by ELISA. Noteworthy, myosin although highly sensitive to the in vitro glutathionylation does not represent the primary glutathionylation target in isolated myofibrils. Light scattering measurements of the glutathionylated α‐actin showed a slower polymerisation compared to the non‐glutathionylated protein and force development was depressed after glutathionylation, when the myofibrils were mounted in a force recording apparatus. Interestingly, confocal laser scanning microscopy of cardiac cryosections indicated, for the first time, the constitutive glutathionylation of α‐cardiac actin in human heart. Due to the critical location of α‐actin in the contractile machinery and to its susceptibility to the oxidative modifications, glutathionylation may represent a mechanism for modulating sarcomere assembly and muscle functionality under patho‐physiological conditions in vivo. © 2009 Wiley‐Liss, Inc.
Respuesta ácido-base a esfuerzos máximos en futbolistas profesionales

El mantenimiento del pH en el organismo en un margen estrecho es de caracter vital para los seres vivos. Esto se debe a la accion amortiguadora de los tampones fisiologicos, que actuan inmediatamente en el medio interno neutralizando las modificaciones en la concentracion de protones. Las acciones reguladoras de pulmon y rinon son las ultimas encargadas de preservar el pH. Con el ejercicio, en un amplio rango de intensidades, el pH se mantiene muy cercano a las cifras basales; a partir de cierta intensidad, desciende en relacion inversa a la carga de trabajo entrando en situacion de acidosis. El objetivo del presente estudio fue describir la respuesta acido-base con un ejercicio de intensidad incremental en futbolistas de elite, profesionales de primer nivel. Del mismo modo, se busco conocer la evolucion de las posibles adaptaciones de los jugadores a esta respuesta homeostatica a lo largo de una temporada. Los resultados obtenidos mostraron el comportamiento de las variables a lo largo del desarrollo del test, sus relaciones entre ellas, asi como la influencia del factor momento de temporada analizado. Los hallazgos de este estudio sugieren que el pH sanguineo de los futbolistas se reduce durante la ejecucion de un ejercicio incremental y la capacidad de amortiguacion disminuye a medida que aumenta el esfuerzo, siendo la frecuencia cardiaca un parametro fiel de medida de la intensidad del test de campo realizado. Por otro lado, los parametros bioquimicos mejoran desde el inicio de la pretemporada al comienzo de la competicion, pudiendo atribuirse a las adaptaciones del entrenamiento; sin embargo, estas variables sufren mayor deterioro al final del campeonato, reflejando el posible agotamiento que se acumula a lo largo del periodo competitivo en los jugadores. Mientras tanto, las adaptaciones de frecuencia cardiaca se mantienen hasta el final del campeonato desde la mejora sufrida al comienzo de la temporada. Este es el primer trabajo que aporta datos relacionados al equilibrio acido-base en futbolistas de elite profesionales de primera division a lo largo de una temporada de futbol, obtenidos de un test de campo especifico para este deporte.