Miracle-dz/UniFAR-FTUs huggingface dataset:
Porphyromonas gingivalis, Treponema denticola and toll-like receptor 2 are associated with hypertensive disorders in placental tissue: a case-control study.

AIM(S) To explore the associations between the presence of periodontal pathogens and the expression of toll-like receptors (TLR-2 and TLR-4) in the placental tissue of patients with hypertensive disorders compared to the placentas of healthy normotensive patients. MATERIAL AND METHODS A case-control study was performed. From a cohort composed of 126 pregnant women, 33 normotensive healthy pregnant women were randomly selected, and 25 cases of patients with hypertensive disorders of pregnancy, including gestational hypertension and pre-eclampsia, were selected. Placental biopsy was obtained after aseptic placental collection at the time of delivery. All of the samples were processed and analysed for the detection of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Treponema denticola and Tannerella forsythia using the polymerase chain reaction (PCR) technique. Determination of the expressions of TLR-2 and TLR-4 was performed in samples of total purified protein isolated from placental tissues and analysed by ELISA. The data were assessed using descriptive statistics. The associations among variables were estimated through multiple logistic regression models and the Mann-Whitney test to evaluate the differences between the two groups. RESULTS A significant increase was observed in the expression of TLR-2 in the placentas of patients with hypertensive disorders (p = 0.04). Additionally, the multiple logistic regression models demonstrated an association between the presence of T. denticola and P. gingivalis in placental tissues and hypertensive disorders (OR: 9.39, p = 0.001, CI 95% 2.39-36.88 and OR: 7.59, p = 0.019, CI 95% 1.39-41.51, respectively). CONCLUSIONS In the present study, pregnant women with periodontal disease presented an association in the placental tissue between the presence of T. denticola and P. gingivalis and hypertensive disorders. Additionally, increased expression of TLR-2 was observed. However, further studies are required to determine the specific roles of periodontal pathogens and TLRs in the placental tissue of patients with pregnancy-related hypertensive disorders.
Opportunities in 3D substrate bonding

Vertical stacking of thin chips combined with Through-Silicon-Vias (TSVs) as interconnects is an attractive path to higher functional density of ICs. Different functional entities of a device are manufactured separately and later integrated by wafer bonding. This enables a modular device architecture and thus a modular manufacturing supply chain. Device manufacturers can focus on their core competence, e.g., designing and building the ASIC, and then add standardized modules, such as logic controllers or memory, from other manufacturers. Stacking dies enables the electrical performance of a system-on-chip, but it reduces the design time, complexity and cost significantly. Wafer bonding is a key manufacturing technology for 3D ICs. Fusion wafer bonding, which was initally developed for SOI wafer manufacturing is the most promising wafer stacking technology for 3D ICs.
Quantitative Tactual-Kinesthetic Judgment

The results of a previous experiment showed that a bilateral kinesthetic difference did not obtain when tactual-kinesthetic judgments were made with the left and right hands. The present experiment was designed to eliminate the possible contribution of visual and kinesthetic figural aftereffects to the directional bias of errors. Results indicate that performance was equivalent with the left and right hands.
Requirement for CD 4 + Cells in Resistance to Pneumocystis caring Pneumonia in Mice

The importance of CD4+ cells in resistance to Pneumocystis carinii (PC) in PC-susceptible severe combined immunodeficient (SCID) mice that were made resistant to PC by immunocompetent spleen cell transfer, and in conventional PC-resistant mice, was investigated . SCID mice with naturally acquired PC pneumonia (PCP) were given infusions of spleen cells from immunocompetent donors. This reconstitution caused the recipients to resolve their PCP. Treatment of reconstituted SCID mice with anti-CD4 monoclonal antibodies (mAbs) to deplete them of CD4+ cells eliminated their ability to resolve PCP, whereas treating them with anti-CD8 mAb to deplete CD8+ cells had no effect . The findings indicate, therefore, that resistance to PCP in immunologically reconstituted SCID mice is dependent on CD4+ cells. To determine whether CD4+ cells enable conventional mice to resist PCP, B6D2 mice were treated with anti-CD4 mAb to deplete them of CD4+ cells in an attempt to induce PCP After 10-11 wk of treatment, these mice developed progressive PCP Taken together, these results indicate that loss of CD4+ cells predisposes mice to PC infection .
Caracterización de los pacientes críticos ventilados en la Fundación Santa Fe de Bogotá 2009 a 2013

Objetivo: Caracterizar a los pacientes que recibieron ventilacion mecanica en las unidades de cuidado intensivo (UCI) de la Fundacion Santa Fe de Bogota entre los anos 2009 y 2013. Metodologia: Se analizo una cohorte retrospectiva de los pacientes en UCI que requirieron soporte ventilatorio mecanico al ingreso a la unidad independientemente de la causa. Resultados: La media de edad de los pacientes fue 63,83 anos; el diagnostico mas frecuente de ingreso fue revascularizacion miocardica, seguido por neumonia y recambio valvular aortico; en el 43% de los casos la causa de la falla fue el estado postoperatorio. Los modos ventilatorios mas frecuentemente utilizados fueron SIMV (27,5%) y ventilacion asistida controlada (26,12%). El 50% de los pacientes fueron ventilados con PEEP < 6 cmH2O. La mortalidad bruta fue del 15%. 22% de los pacientes tuvieron estancia prolongada en UCI. Se aplico protocolo de retiro de ventilacion mecanica en el 77% de los pacientes. La duracion de la ventilacion mecanica es mayor a medida que aumenta la edad del paciente entre los 60 y los 80 anos. La mortalidad es cercana al 50% alrededor de los 50 anos y mayor a 80% despues de los 80 anos. El soporte ventilatorio por cinco o mas dias aumento la mortalidad a 80% o mas. Discusion y Conclusiones: Estos resultados son comparables a los encontrados en estudios previos. Este estudio puede ser considerado como el primer paso para generar un registro adecuado de la ventilacion de la mecanica de las unidades de cuidado intensivo del pais.
Routing protocols for wireless sensor networks with mobile sinks: a survey

Wireless sensor networks with mobile sinks, mWSNs, have attracted a lot of attention recently. This is because sink mobility can greatly alleviate the hotspot issue in WSNs and further prolong the network lifetime. However, sink mobility also causes unexpected changes in network topology and data routing paths, which can largely affect the routing performance in such networks. Design of efficient routing protocols for mWSNs has been a critical issue, and much work has been carried out in this aspect. In this article, we first classify existing protocols based on different design criteria and then present a survey of the state-of-the-art routing protocols in this area. We illustrate how each of the protocols works, and discuss their advantages and disadvantages. Finally, we point out some future directions for efficient routing in mWSNs.
Sentiment Classification of Twitter Data Belonging to Saudi Arabian Telecommunication Companies

Twitter has attracted the attention of many re-searchers owing to the fact that every tweet is, by default, public in nature which is not the case with Facebook. In this paper, we present sentiment analysis of tweets written in English, belonging to different telecommunication companies in Saudi Arabia. We apply different machine learning algorithms such as k nearest neighbor algorithm, Artificial Neural Networks (ANN), Na¨ive Bayesian etc. We classified the tweets into positive, negative and neutral classes based on Euclidean distance as well as cosine similarity. Moreover, we also learned similarity matrices for kNN classification. CfsSubsetEvaluation as well as Information Gain was used for feature selection. The results of CfsSubsetEvaluation were better than the ones obtained with Information Gain. Moreover, kNN performed better than the other algorithms and gave 75.4%, 76.6% and 75.6% for Precision, Recall and F-measure, respectively. We were able to get an accuracy of 80.1%with a symmetric variant of kNN while using cosine similarity. Furthermore, interesting trends wrt days, months etc. were also discovered.
Terrain aided navigation application for airborne platforms

Performances of Inertial Navigation Systems (INS) degrade as time elapses. In order to keep error on navigation information of airborne platforms which use these kinds of navigation systems bounded, additional aid systems are used. Global Positioning Satellite Systems (GPSS) are aid systems which are widely used. Since their errors are bounded, they are used as aid to INSs within Kalman Filter applications. Although their wide usage, it is very easy to keep Global Satellite Positioning Systems out of service locally. In such cases, inertial navigation systems become aidless and their performances degrade with time. When Global Satellite Positioning Systems are unavailable, Terrain Based Positioning Systems (TBPS) are used as aid to inertial systems. TBPSs are based on a positioning method where terrain profiles, which are obtained by using onboard sensors, are compared with a preloaded digital terrain elevation map. In this paper, two different positioning methods are discussed and evaluated by using the simulation results obtained at 10 different flight paths.
A Roadmap towards Declarative Similarity Queries

Despite many research efforts, similarity queries are still poorly supported by current systems. We analyze the main stream research in processing similarity queries and argue that a generalpurpose query processor for similarity queries is required. We identify three goals for the evaluation of similarity queries (declarative, efficient, combinable) and identify the main research challenges that must be solved to achieve these goals.
Leptin secretion and leptin receptor in the human stomach

BACKGROUND AND AIM The circulating peptide leptin produced by fat cells acts on central receptors to control food intake and body weight homeostasis. Contrary to initial reports, leptin expression has also been detected in the human placenta, muscles, and recently, in rat gastric chief cells. Here we investigate the possible presence of leptin and leptin receptor in the human stomach. METHODS Leptin and leptin receptor expression were assessed by immunohistochemistry, reverse transcriptase-polymerase chain reaction (RT-PCR), and western blot analysis on biopsy samples from 24 normal individuals. Fourteen (10 healthy volunteers and four patients with non-ulcer dyspepsia and normal gastric mucosa histology) were analysed for gastric secretions. Plasma and fundic mucosa leptin content was determined by radioimmunoassay. RESULTS In fundic biopsies from normal individuals, immunoreactive leptin cells were found in the lower half of the fundic glands. mRNA encoding ob protein was detected in the corpus of the human stomach. The amount of fundic leptin was 10.4 (3.7) ng leptin/g mucosa, as determined by radioimmunoassay. Intravenous infusions of pentagastrin or secretin caused an increase in circulating leptin levels and leptin release into the gastric juice. The leptin receptor was present in the basolateral membranes of fundic and antral gastric cells. mRNA encoding Ob-RL was detected in both the corpus and antrum, consistent with a protein of ∼120 kDa detected by immunoblotting. CONCLUSION These data provide the first evidence of the presence of leptin and leptin receptor proteins in the human stomach and suggest that gastric epithelial cells may be direct targets for leptin. Therefore, we conclude that leptin may have a physiological role in the human stomach, although much work is required to establish this.
Psychopathy and the combination of psychopathy and sexual deviance as predictors of sexual recidivism: meta-analytic findings using the Psychopathy Checklist--Revised.

Clinicians routinely administer Hare's (2003) Psychopathy Checklist-Revised (PCL-R) to sex offenders and report PCL-R scores as meaningful predictors of recidivism risk. Although a 2005 meta-analysis reported a small (d=0.29) association between PCL-R scores and sexual recidivism (Hanson & Morton-Bourgon, 2005), no meta-analysis has examined effects for PCL-R factors and facets, the widely cited combination of high PCL-R and high sexual deviance scores, or potential moderators of the PCL-R/recidivism relation. We conducted a meta-analysis of effects from all available studies examining the relation between PCL-R scores and sexual recidivism (k=20, N=5,239). The effect for PCL-R Total scores predicting sexual recidivism was d=0.40, which falls beyond the upper end of the 2005 confidence interval [. 20, . 38]. Effects were stronger for Factor 2 (d=0.44) and Facet 4 (d=0.40) scores than other factor or facet scores (ds=0.01 to 0.17). Effects tended to be stronger for scores calculated for research (d=0.44) compared to those calculated for clinical use (d=0.28). Offenders who scored high on both the PCL-R and a measure of sexual deviance were more likely to reoffend sexually than other offenders (odds ratio=2.80 to 3.21, k=6). Results indicate that PCL-R scores, particularly combined with a measure of sexual deviance, are potentially relevant to sex offender risk. But results also underscore several practical challenges to implementing these findings in routine clinical practice.
La Tasa De Retorno De La Educación: Teoría Y Evidencia Micro Y Macroeconómicas En El Área Metropolitana De Cali 1988-2000

El objetivo de este documento es proponer y someter a la evidencia empirica una aproximacion teorica a la evolucion y determinantes de la tasa de retorno de la educacion, integrando las dimensiones micro y macroeconomicas de la tasa de salarios individual y utilizando los desarrollos de la micro y macroeconometria contemporaneas. El sustento empirico son las 52 Encuestas Nacionales de Hogares para el area metropolitana de Cali que van desde 1988 hasta el 2000.
T. S. Eliot and the Concept of Tradition

Foreword Sir Frank Kermode Introduction Giovanni Cianci and Jason Harding Part I. Tradition and Impersonality: 1. Exorcising the demon of chronology: T. S. Eliot's reinvention of tradition Aleida Assmann 2. Proper frontiers: transgression and the individual talent Stan Smith 3. Writing the self: dialectic and impersonality in T. S. Eliot Jewel Spears Brooker 4. The later fortunes of impersonality: 'Tradition and the Individual Talent' and post-war poetry Clive Wilmer Part II. Contexts - Literary: 5. French influences and echoes in 'Tradition and the Individual Talent' Bernard Brugiere 6. Tradition and egoism: T. S. Eliot and The Egoist Jason Harding 7. Tradition in 1919: Pound, Eliot and the 'historical method' Massimo Bacigalupo Part III. Contexts - Art and Anthropology: 8. Reading T. S. Eliot visually: tradition in the context of modernist art Giovanni Cianci 9. Some art historical contexts for 'Tradition and the Individual Talent' Michael Hollington 10. 'A living whole': from T. S. Eliot's tradition to Hans Blumenberg's work on myth Claudia Corti 11. Whose tradition? : T. S. Eliot and the text of anthropology Caroline Patey Part IV. Case Studies: 12. Duchamp's Eliot: the detours of tradition and the persistence of individual talent Marjorie Perloff 13. Tradition and the march of literature: T. S. Eliot and Ford Madox Ford Max Saunders 14. At the frontiers of metaphysics: time and history in T. S. Eliot and Walter Benjamin Brett Neilson Select bibliography Index.
Learning Forum Posts Topic Discovery and Its Application in Recommendation System

What a network learner post on a network learning forum directly reflects the learners’ need during from the network learning process. The network learning supporting service could be greatly improved with mining topics from the forum posts. For this purpose, this paper employs the Learner-Topic (LT) model to mine learners’ posts and discover the topics. The results from the model are used to search the learners who have the same learning interest and recommend the learning resources in a recommendation system.
Hot water systems as sources of Legionella pneumophila in hospital and nonhospital plumbing fixtures

Samples obtained from plumbing systems of hospitals, nonhospital institutions and homes were cultured for Legionella spp. by plating the samples directly on a selective medium. Swab samples were taken from the inner surfaces of faucet assemblies (aerators, spouts, and valve seats), showerheads, and shower pipes. Water and sediment were collected from the bottom of hot-water tanks. Legionella pneumophila serogroups 1, 5, and 6 were recovered from plumbing fixtures of the hospitals and nonhospital institutions and one of five homes. The legionellae (7 to 13,850 colony-forming units per ml) were also present in water and sediment from hot-water tanks maintained at 30 to 54 degrees C, but not in those maintained at 71 and 77 degrees C. Legionella micdadei was isolated from one tank. Thus legionellae are present in hot-water tanks which are maintained at warm temperatures or whose design results in warm temperatures at the bottom of the tanks. We hypothesize that hot-water tanks are a breeding site and a major source of L. pneumophila for the contamination of plumbing systems. The existence of these bacteria in the plumbing systems and tanks was not necessarily associated with disease. The extent of the hazard of this contamination needs to be delineated.
Deep--deeper--deepest? Encoding strategies and the recognition of human faces.

Various encoding strategies that supposedly promote deeper processing of human faces (e.g., character judgments) have led to better recognition than more shallow processing tasks (judging the width of the nose). However, does deeper processing actually lead to an improvement in recognition, or, conversely, does shallow processing lead to a deterioration in performance when compared with naturally employed encoding strategies? Three experiments systematically compared a total of 8 different encoding strategies manipulating depth of processing, amount of elaboration, and self-generation of judgmental categories. All strategies that required a scanning of the whole face were basically equivalent but no better than natural strategy controls. The consistently worst groups were the ones that rated faces along preselected physical dimensions. This can be explained by subjects' lesser task involvement as revealed by manipulation checks.
IFN-gamma increases efficiency of DNA vaccine in protecting ducks against infection.

AIM To detect the effects of DNA vaccines in combination with duck IFN-gamma gene on the protection of ducks against duck hepatitis B virus (DHBV) infection. METHODS DuIFN-gamma cDNA was cloned and expressed in COS-7 cells, and the antiviral activity of DuIFN-gamma was detected and neutralized by specific antibodies. Ducks were vaccinated with DHBpreS/S DNA alone or co-immunized with plasmid expressing DuIFN-gamma. DuIFN-gamma mRNA in peripheral blood mononuclear cells (PBMCs) from immunized ducks was detected by semi-quantitative competitive RT-PCR. Anti-DHBpreS was titrated by enzyme-linked immunosorbent assay (ELISA). DHBV DNA in sera and liver was detected by Southern blot hybridization, after ducks were challenged with high doses of DHBV. RESULTS DuIFN-gamma expressed by COS-7 was able to protect duck fibroblasts against vesicular stomatitis virus (VSV) infection in a dose-dependent fashion, and anti-DuIFN-gamma antibodies neutralized the antiviral effects. DuIFN-gamma in the supernatant also inhibited the release of DHBV DNA from LMH-D2 cells. When ducks were co-immunized with DNA vaccine expressing DHBpreS/S and DuIFN-gamma gene as an adjuvant, the level of DuIFN-gamma mRNA in PBMCs was higher than that in ducks vaccinated with DHBpreS/S DNA alone. However, the titer of anti-DHBpreS elicited by DHBpreS/S DNA alone was higher than that co-immunized with DuIFN-gamma gene and DHBpreS/S DNA. After being challenged with DHBV at high doses, the load of DHBV in sera dropped faster, and the amount of total DNA and cccDNA in the liver decreased more significantly in the group of ducks co-immunized with DuIFN-gamma gene and DHBpreS/S DNA than in other groups. CONCLUSION DHBV preS/S DNA vaccine can protect ducks against DHBV infection, DuIFN-gamma gene as an immune adjuvant enhances its efficacy.
Haemophilus influenzae acquires vitronectin via the ubiquitous Protein F to subvert host innate immunity

Acquisition of the complement inhibitor vitronectin (Vn) is important for the respiratory tract pathogen nontypeable Haemophilus influenzae (NTHi) to escape complement‐mediated killing. NTHi actively recruits Vn, and we previously showed that this interaction involves Protein E (PE). Here we describe a second Vn‐binding protein, a 30 kDa Yersinia YfeA homologue designated as Protein F (PF). An isogenic NTHi 3655Δhpf mutant devoid of PF displayed a reduced binding of Vn, and was consequently more sensitive to killing by human serum compared with the wild type. Surface expression of PF on Escherichia coli conferred binding of Vn that resulted in a serum resistant phenotype. Molecular analyses revealed that the N‐terminal of PF (Lys23‐Glu48) bound to the C‐terminal of Vn (Phe352‐Ser374) without disrupting the inhibitory role of Vn on the membrane attack complex. The PF–Vn complex actively delayed C9 deposition on PF‐expressing bacteria. Comparative studies of binding affinity and multiple mutants demonstrated that both PE and PF contribute individually to NTHi serum survival. PF was highly conserved and ubiquitously expressed in a series of randomly selected NTHi clinical isolates (n = 18). In conclusion, the multifaceted binding of Vn is beneficial for NTHi survival in serum and may contribute to successful colonization and consequently infection.
Synthèse des travaux de recherche sur la Télé-université

Des treize (13) recherches realisees par l’INRS-Education en relation avec la premiere implantation du cours COOP-001 et des huit (8) recherches menees conjointement par l’INRS-Education et la Tele-universite, portant sur les caracteristiques de l’apprenant-adulte et le personnel de support dans un systeme multi-media de formation a distance, nous degageons ce qu’il a ete permis d’observer quant aux quatre (4) points suivants : On termine en formulant des recommandations suggerant des ameliorations a apporter aux divers secteurs d’activite de la Tele-universite et visant l’orientation des travaux ulterieurs de recherche.
Hypercalcemic and hypophosphatemic effects of dibutyryl cyclic AMP in rats after parathyroidectomy.

In parathyroidectomized (PTX) rats, administration of dibutyryl cyclic AMP (DB-CAMP), but not cyclic AMP (CAMP) itself, caused an elevation in serum calcium and a decline in serum phosphorus. In intact rats, DB-CAMP had no detectable effect on serum calcium, but depressed serum phosphorus. The hypercalcemic effect of DB-CAMP was slightly enhanced after thyroparathyroidectomy. The rapid fall in serum calcium which follows acute PTX by hot wire cautery was partially inhibitedinhibited by DB-CAMP. Pretreatment with theophylline enhanced the hypercalcemic effect of DB-CAMP. The hypercalcemic effect of DBCAMP was antagonized by thyrocalcitonin or imidazole. It is concluded that the similarities in the effects of DB-CAMP and parathyroid extract support the hypothesis that CAMP is an important mediator of at least some of the actions of parathyroid hormone. (Endocrinology 84: 861,1969)