Suggestions on Prevention and Treatment of 2019 Novel Coronavirus with Traditional Chinese Medicine

In fact, most of the patients are in the early stage of infection, if given reasonable treatment, they can recover quickly. On the other hand, there is a recurrence of infection after rehabilitation that is also a risk factor for healthy people. In Henan Province of China, 14 patients were treated with integrated traditional Chinese and Western medicine after 2019-nCoV infection was diagnosed. We found that the final cure rate was 100% and there is none recurrence of infection, so far. Suofeng Sun* and Weiwu RD Henan Provincial People’s Hospital and The People’s Hospital of Zhengzhou University, Henan, China Introduction At present, the new coronavirus has been popular all over the world, which has brought heavy pressure to the medical system of various countries [1]. A document was issued in January 23rd, 2020 to establish a synergistic mechanism for the 2019-nCoV. The provincial expert group is on duty in combination with traditional Chinese and Western medicine to carry out long-distance consultation with traditional Chinese and Western medicine for severe cases, so as to achieve full coverage. Treatment of 2019 Novel Coronavirus with Traditional Chinese Medicine In March 2020, we collected 14 patients' treatment information from the First Affiliated Hospital of Henan University of traditional Chinese medicine, Xinmi Hospital of traditional Chinese medicine and Lushi Hospital of traditional Chinese medicine. 14 patients were treated with integrated traditional Chinese and Western medicine after 2019-nCoV infection was diagnosed. According to the clinical manifestations and syndrome characteristics, 14 patients were treated with different traditional Chinese medicine, which was Decoction and orally taken. Traditional Chinese Medicine treatment combined with syndrome changes are divided into period of medical observation and Clinical treatment period. Clinical treatment period is divided into early stage, Metaphase, Severe stage, Recovery period. Finally, we recommend different traditional Chinese medicine treatment according to the pathological characteristics and clinical manifestations of each stage combined with Western Medicine, the treatment plan of medical observation period is shown in Table 1 and the treatment plan of clinical treatment period is in Table 2. 14 patients' treatment information is shown in Table 3. That is from the First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Xinmi Hospital of traditional Chinese medicine and Lushi Hospital of traditional Chinese medicine were treated with integrated traditional Chinese and Western medicine. We found that the final cure rate Clinical feature Recommended Chinese patent drug Dose/ day Medication method Medical observation period Feeble with gastrointestinal discomfort Huoxiang Zhengqi Capsule 3.6 g Oral Feeble with fever Lianhua Qingwen capsule 4.2 g Oral Table 1: Treatment scheme of medical observation period. Clinical feature Recommended prescription Dose/day Clinical treatment period Initial stage Aversion to cold with fever, dry cough, dry throat, fatigue, chest tightness, wanruff, or nausea, loose stools. The tongue is light or reddish, the moss is white and greasy, and the pulse is moistening. Cangshu 15 g, tangerine peel 10 g, magnolia officinalis 10 g, huoxiang 10 g, caoguo 6 g, raw ephedra 6 g, notopterygium 10 g, ginger 10 g, betel 10 g 600 ml Table 2: Treatment scheme of clinical treatment period. Suofeng Sun, et al., Clinics in Surgery General Surgery Remedy Publications LLC. , | http://clinicsinsurgery.com/ 2020 | Volume 5 | Article 2805 2 was 100%. Further research shows that the specific pharmacological effects of these effective Chinese herbs can well control the storm of inflammatory factors brought by new coronavirus. Results were showed in Table 4. Discussion The incubation period of 2019-nCoV infection is 19 days; the longest can reach 24 days [2]. It turns out that asymptomatic virus carriers can also infect people. The epidemic has seriously endangered the lives and health of all human beings, so it is necessary to develop specific antiviral drugs. According to the results of the treatment of the 2019-nCoV in Henan Province of China, the Chinese medicine has played an important role. Therefore, we strongly recommend Chinese medicine's strategy for the prevention and treatment of new coronavirus to all countries in the world. Author Contributions Dr. Li had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Hospital Name Number of infected persons Therapeutic method Cure rate First Affiliated Hospital of Henan University of traditional Chinese medicine 8 Integrated traditional Chinese and Western medicine 100% Xinmi Hospital of traditional Chinese medicine 3 Integrated traditional Chinese and Western medicine 100% Lushi Hospital of traditional Chinese medicine 3 Integrated traditional Chinese and Western medicine 100% Table 3: 14 patient's treatment information. Chinese medicine name Ephedra Licorice Chinese Atractylodes Polygonum cuspidatum Agastache rugosus Almond Effective components of traditional Chinese Medicine Ephedrine Liquiritigenin Atractylodin Emodin Apigenin Lauric acid Target TP53 Caspase ICAM1, ICAM2 Toll-like receptors (TLR4, TLR9) TNF receptor Interferon PTGS1/2, HSP90 Table 4: Target of traditional Chinese medicine. Concept and design: Sun. Acquisition, analysis, or interpretation of data: Li, Sun. Drafting of the manuscript: Li, Sun. Critical revision of the manuscript for important intellectual content: Li, Sun. Statistical analysis: Li, Sun. Administrative, technical, or material support: Li, Sun. Supervision: Li, Sun. References 1. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet. 2020;S0140-6736(20)30566-3. 2. Zheng F, Liao C, Fan Q-H, Chen H-B, Zhao X-G, Xie Z-GG, et al. Clinical characteristics of children with coronavirus disease 2019 in Hubei, China. Curr Med Sci. 2020;24:1-6.