Miracle-dz/UniFAR-FTUs huggingface dataset:
GROWTH OF TWO FACULTATIVELY HETEROTROPHIC MARINE CENTRIC DIATOMS 1, 2

The facultative, heterotrophs Cyclotella cryptica (sclone WT‐1‐8) and Coscinodiscus sp. were selectively isolated from coastal waters by dark incubation of organically enriched solid medium. C. cryptica grows in the dark with glucose and galactose, and Coscinodiscus sp. with glucose. Clone WT‐1‐8 of C. cryptica grows about twice as fast with glucose as a previously studied clone (0‐3A). In the dark with, 5 × 10−6 M glucose C. cryptica divides every 3 days, while with 5 × 10−5 M glucose Coscinodiscus sp. divides every 10 days. Heterotrophic growth of either diatom for 1 year does not cause a major reduction in carbon, nitrogen, chlorophyll a, and chlorophyll c contents, or in photosynthetic ability, compared to light‐grown cells. It is possible that facultative heterotrophy is of ecological benefit to these diatoms, probably for slow growth and survival during extended periods of dim light or darkness.
Quantitative trait loci for carcass, internal organ and meat quality traits on porcine chromosomes 16, 17 and 18

The objective of this study was to map quantitative trait loci (QTL) on porcine chromosomes 16, 17 and 18 and to determine their association with carcass, organ and meat quality traits. An F2 population was produced by crossing two boars of the naturalized Brazilian Piau breed with 18 commercial females (Landrace x Large White x Pietrain). The population was genotyped for 11 microsatellite markers distributed over the three chromosomes and the results were used to construct a marker-specific linkage map for the population. Analysis of the polymorphic information content showed that the microsatellite markers were adequate for the study of quantitative traits. QTL were identified by regression interval mapping using QTL Express software. QTL not previously described in the literature were detected on chromosome 16, whereas QTL described in other populations were detected on chromosomes 17 and 18. The information from the significant QTL identified here will be useful for future fine-mapping studies and should provide a better understanding of productive phenotypes in pigs.
Medication Adherence Patterns to Anti-diabetic Drugs among Type 2 Diabetic Patients

Introduction: The aim of the present study was to evaluate the pattern of medication adherence to anti-diabetic drugs among type 2 diabetic patients at two tertiary level hospitals in Mymensingh. Materials and Methods: An observational, cross sectional study was conducted from January 2016 to June 2016 among patients attending at Endocrine Outpatient Department of the Mymensingh Medical College Hospital and Medicine Outpatient Department of the Community Based Medical College Hospital, after obtaining requisite consent from the patients. Once the consultation by the physician was over, the patients were interviewed. Medication adherence was assessed through the specific four questions patient questionnaire, the modified morisky instrument that has high reliability and validity and the patient was considered to be highly adherent if he or she answered in the negative to all four questions (score-0). Results: In a pool of 300 type 2 diabetics, more than half were female (n=223, 74.3%). The mean age of the patients were found to be 50.59 ± 12.57 years. Less than half (37%) of the patients were considered highly adherent, 44% patients were considered moderately adherent and 19% patients were considered poorly adherent to the prescribed anti-diabetic drugs. Conclusion: The participants in the area of study were moderately adherent to their anti-diabetic medications. Measures should be taken to improve patient’s adherence to the prescribed treatment. Medicine Today 2019 Vol.31(1): 19-22
Relationship between steroid hormones and maternal characteristics and larvae in Persian sturgeon Acipenser persicus

Abstract The reproductive biology of fish has been a field of wide interest. The aim of this study was to determine the correlations between sex steroid hormones and maternal characteristics and larvae in the Persian sturgeon Acipenser persicus. The blood samples were derived from 22 female specimens in reproductive stage IV (migration of nucleus) for measuring testosterone (T), 17β-estradiol (E2), and progesterone (P4). As a result, T demonstrated a significant correlation with E2 (r= 0.44) and P4 showed a significant relationship (P < 0.05) only with the larval survival rate after the feeding stage (r= 0.52), but other variables did not demonstrate any significant correlation with one another. There was not a significant relationship in female Persian sturgeon between steroid hormones and size.
Too Busy to Be Manipulated: How Multitasking with Technology Improves Deception Detection in Collaborative Teamwork

ABSTRACT Deception is an unfortunate staple in group work. Guarding against team members’ deceptive tactics and alternative agendas is difficult and may seem even more difficult in technology-driven business environments that have made multitasking during teamwork increasingly commonplace. This research develops a foundation for a nuanced theoretical understanding of deception detection under these conditions. The intersection of information technology multitasking and deception detection theories is shown to produce various and sometimes competing ideas about how this type of multitasking might affect truthfulness assessments in real-time teamwork. A laboratory study involving a collaborative game helped evaluate the different ideas using manipulated deception and multitasking behaviors in a real-time, virtual group environment. The results provide evidence that information multitasking can actually improve deception detection, likely because multitaskers engage less in the team conversation, making themselves less manipulable. As understanding of multitasking benefits increases, managers and designers can incorporate effective multitasking into collaborative processes.
Experimento sobre calidad externa con Test-Driven Development en la industria de telecomunicaciones

Test-Driven Development (TDD) is a software development technique and studies in TDD increased in the last fifteen years. TDD promises positive effects in the development process, however there are few studies in the industrial field. To verify is the TDD programming technique increases the quality of software a controlled experiment was conducted comparing the software development technique TDD (Test-Driven Development) with ITL (Iterative Test Last) and the technique of the ETAPA EP1 Telecommunications Company. The experiment was implemented according to the software engineering experimental process. The analysis clearly shows that quality-wise ITL is statistically significant superior to TDD. ITL increases the quality of the source code of the subject. From the practical point of view, ITL produces better code quality than the ETAPA EP development technique, however in comparison with the TDD approach increases the ETAPA EP technique the quality, but not to the extent as the ITL technique. The experiment allowed to define practical recommendations regarding the development process used in ETAPA EP.
STUDIES ON THE LIFE CYCLES AND MORPHOLOGY OF THE LARVAL STAGES OF ALARIA ARISAEMOIDES AUGUSTINE AND URIBE, 1927 AND ALARIA CANIS LARUE AND FALLIS, 1936 (TREMATODA: DIPLOSTOMIDAE)

A. arisaemoides and A. canis have three-host life cycles. In both species there is a mesocercarial stage interpolated between the cercarial and the metacercarial stages. The mesocercaria develops in the second intermediate host and is infective for the definitive host. In the lungs of the definitive host the mesocercariae develops into a diplostomulum which in turn develops into an adult in the small intestine. Mesocercariae survive without developing further in a variety of paratenic hosts, for example, certain frogs, snakes, birds, and mammals. The morphology of the larval stages and the intramolluscan generations is described and observations on the following are given: rate of development, hatching of the egg, and swimming of the miracidium of A. arisaemoides; route of emergence from the snail host, variations in emergence, time of emergence and numbers emerging, activity, and penetration of the second intermediate host by the cercariae; and locomotion and the change in distribution of the mesocercari.
A Comparison of Calcified Structures for Aging Bluefish in the Chesapeake Bay Region

Abstract We compared whole and sectioned otoliths, scales, dorsal spine sections, opercular bones, and vertebrae for aging bluefish Pomatomus saltatrix from the Chesapeake Bay region. Opercular bones and vertebrae were unusable; they were spongy and pitted, and contained no visible marks. The remaining structures exhibited concentric rings that were interpreted as annual marks; however, structures differed greatly in mark clarity. Over the age range 1-14 years, sectioned otoliths were the best structure, consistently showing the clearest marks, highest confidence scores, and highest within- and between-reader agreement. Whole otoliths were the second best structure, providing the second highest overall within-reader agreement and 95% agreement with sectioned otoliths to age 4. Scales were inferior to sectioned and whole otoliths, especially after age 4, when within-reader agreement was only 33% and agreement with sectioned otoliths was only 26%. Dorsal spine sections were undesirable for aging bluefish, p.
The concentration of xylem sap constituents in root exudate, and in sap from intact, transpiring castor bean plants (Ricinus communis L.)

Root exudates were sampled from detopped root systems of castor bean (Ricinus communis). Different volume flux rates were imposed by changing the pneumatic pressure around the root system using a Passioura-type pressure chamber. The concentrations of cations, anions, amino acids, organic acids and abscisic acid decreased hyperbolically when flux rates increased from pure root exudation up to values typical for transpiring plants. Concentrations at low and high fluxes differed by up to 40 times (phosphate) and the ratio of substances changed by factors of up to 10. During the subsequent reduction of flux produced by lowering the pneumatic pressure in the root pressure chamber, the concentrations and ratios of substances deviated (at a given flux rate) from those found when flux was increased. The flux dependence of exudate composition cannot therefore be explained by a simple dilution mechanism. Xylem sap samples from intact, transpiring plants were collected using a Passioura-type root pressure chamber. The concentrations of the xylem sap changed diurnally. Substances could be separated into three groups: (1) calcium, magnesium and amino acid concentrations correlated well with the values expected from their concentration-flux relationships, whereas (2) the concentrations of sulphate and phosphate deviated from the expected relationships during the light phase, and (3) nitrate and potassium concentrations in intact plants varied in completely the opposite manner from those in isolated root systems. Abscisic acid concentrations in the root exudate were dependent on the extent of water use and showed strong diurnal variations in the xylem sap of intact plants even in drought-stressed plants. Calculations using root exudates overestimated export from the root system in intact plants, with the largest deviation found for proton flux (a factor of 10). We conclude that root exudate studies cannot be used as the sole basis for estimating fluxes of substances in the xylem of intact plants. Consequences for studying and modelling xylem transport in whole plants are discussed
Can You Hear Me? A Metric for Link Asymmetry

The Internet of Things is a networking paradigm aiming to provide computing pervasiveness to our everyday lives. A key component to the Internet of Things is low power networks that gather information from the environment. Low power networks are prone to asymmetric and unidirectional links. Measuring the level of asymmetry and understanding its sources are key steps to successfully deploying sensor networks and the Internet of Things. Our first contribution is a new metric to assess link asymmetry, one which takes into account the instantaneous delivery success probability. Next, we study the influence of four factors on link asymmetry in light of our asymmetry metric, namely, relative distance, output power, relative position, and hardware heterogeneity. With our unique method, we show that all four factors impact link asymmetry.
Reconstruction of Random Media via Multi-Objective Optimization

To simplify numerical analyzes of complicated real microstructures, a material representation in terms of Representative Volume Element (RVE) has been introduced. It is based on a binary (black and white) image, which statistically resembles the corresponding real microstructure. To characterize microstructure and assess the proximity of the compressed representation to the reference microstructure, several statistical descriptors are usually employed. In one of the approaches to construction of RVE, a unit cell is derived from the optimization procedure formulated in terms of selected statistical descriptors. The aim of our work is to resolve this issue by multi-objective optimization techniques. The goal is to approximate as closely as possible the true Pareto front as a trade-off of competing objectives.
HUBUNGAN ANTARA MEROKOK DENGAN IMT (INDEKS MASSA TUBUH) MAHASISWA S1 UNIVERSITAS TANJUNGPURA, KALIMANTAN BARAT

Latar Belakang: Survei secara nasional menemukan hampir 2/3penduduk dari kelompok umur produktif adalah perokok. Penelitian SunHa Jee et al, mendapat hasil bahwa IMT perokok di Jepang lebih rendahdibandingkan bukan perokok. Hal ini juga didukung oleh penelitian PragtiChhabra dan Sunil K. Chhabra, yang mendapatkan hasil bahwa perokok diIndia mempunyai IMT kategori dibawah normal 30% lebih banyakdibandingkan bukan perokok dan dari 99 studi didapatkan hasil pria yangsehari-harinya merokok mempunyai IMT rendah 3% lebih banyakdaripada pria bukan perokok. Tujuan: Penelitian ini bertujuan untukmengetahui hubungan antara merokok dengan IMT mahasiswa S1Universitas Tanjungpura. Metodologi: Desain penelitian analitik denganpendekatan potong lintang. Jumlah sampel sebanyak 242 orang, terdiridari 126 current smoker dan 116 never smoker. Hasil: Current smokermempunyai kecenderungan 1,93 kali lebih tinggi untuk memiliki IMT <18,5dibandingkan never smoker. Kesimpulan: Merokok memiliki hubunganyang bermakna dengan IMT.
Loss of Hap1 selectively promotes striatal degeneration in Huntington disease mice

Significance A variety of neurodegenerative diseases show selective neuronal loss in distinct brain regions. It remains unclear how the ubiquitously expressed disease proteins can cause selective neurodegeneration. In Huntington’s disease, neuronal loss preferentially occurs in the striatum. Using Huntington’s disease mice, we found that loss of Hap1 selectively causes neuronal degeneration in the striatum. We further identified that this selective neuronal degeneration also depends on mutant HTT and Rhes, a striatal enriched protein. Hap1 deficiency causes more Rhes to bind mutant HTT to yield a toxic form of mutant HTT. Our findings suggest that multiple factors are involved in the selective neuronal loss in neurodegenerative diseases and that their specific interaction can serve as a therapeutic target. Huntington disease (HD) is an ideal model for investigating selective neurodegeneration, as expanded polyQ repeats in the ubiquitously expressed huntingtin (HTT) cause the preferential neurodegeneration in the striatum of the HD patient brains. Here we report that adeno-associated virus (AAV) transduction-mediated depletion of Hap1, the first identified huntingtin-associated protein, in adult HD knock-in (KI) mouse brains leads to selective neuronal loss in the striatum. Further, Hap1 depletion-mediated neuronal loss via AAV transduction requires the presence of mutant HTT. Rhes, a GTPase that is enriched in the striatum and sumoylates mutant HTT to mediate neurotoxicity, binds more N-terminal HTT when Hap1 is deficient. Consistently, more soluble and sumoylated N-terminal HTT is presented in HD KI mouse striatum when HAP1 is absent. Our findings suggest that both Rhes and Hap1 as well as cellular stress contribute to the preferential neurodegeneration in HD, highlighting the involvement of multiple factors in selective neurodegeneration.
Comparison of performance of various leg-kicking techniques in fin swimming in terms of achieving the different goals of underwater activities

The aim of this study was to compare underwater fin swimming performance using dolphin, flutter and breaststroke kicks with and without diving gear. Performance was evaluated in terms of average swimming velocity. The parameters of spatiotemporal structure of the stroke reflecting to the swimming economy were employed. Conscious modifications in propulsion technique were considered here with the aim of controlling swimming performance. A total of ten professional scuba divers swam at maximal speed underwater for 50m using each of three techniques: dolphin, flutter, or breaststroke kicks. Swimmers’ performance was compared between holding their breath and using breathing apparatus. Two cameras recorded their movements in sagittal and transverse planes. The average swimming velocity (vav), stroke length (SL), stroke rate (SR), index of variation of intracycle velocity (VIVIndex) and stroke index (SI) were estimated. Relative to the other techniques, the dolphin kick without a diving gear demonstrated the highest vav and low SI and VIVIndex values, which reflects the most advantageous economy of propulsion at given velocity. Given the lack of statistical differences, using the breaststroke kick and flutter kick when swimming with a diving gear seems to be comparable to dolphin-kick in terms of average velocity and parameters reflecting the economy of propulsion. Thus, a search for fin swimming techniques with the aim of achieving specific goals seemed reasonable. The results suggest, that performance achieved while using various fin swimming techniques was probably controlled by different strategies of leg movements. These strategies revealed differences in a spatiotemporal (SR-SL) structure of the stroke and they were closely associated in terms of the velocity variation decrease.
Genetic aspects in schizophrenia. Receptoral theories. Metabolic theories

Ties between schizophrenia (SCZ) and genetics are undeniably significant issue prone to be discussed in the nowadays psychology. Recent research on this domain focuses more on specific genes and heredity (specifically monozygotic pairs of twins) for diagnosing SCZ, than on environmental influences. SCZ is considered a multifactorial disease, thought to convert from a merger of risk and biological genes and environmental factors that could alter and reshape the trajectory of brain development. On this regard, this review sums up recent and innovative methods of distinguishing schizophrenic features from other mental illnesses in patients, based on chromosomal and genes changes. The term “reverse genetics” is no longer up to date, being replaced with “genome scanning” and “positional cloning”. For many researchers, genome scanning is continuing the reverse of the sensible strategy for detecting various important biological disorders, which may start from the discovery of a protein or any other molecule involved in a biological process, being followed by its gene cloning. Genes being discovered in this manner could become candidate genes for the disease. However, genome scanning occurs through testing each chromosomal segment (or mitochondrial genome) for the counter transmission of the disease.
User Adaptation to Closed-Loop Decoding of Motor Imagery Termination

One of the most popular methods in non-invasive brain machine interfaces (BMI) relies on the decoding of sensorimotor rhythms associated to sustained motor imagery. Although motor imagery has been intensively studied, its termination is mostly neglected. Objective: Here, we provide insights in the decoding of motor imagery termination and investigate the use of such decoder in closed-loop BMI. Methods: Participants (N = 9) were asked to perform kinesthetic motor imagery of both hands simultaneously cued with a clock indicating the initiation and termination of the action. Using electroencephalogram (EEG) signals, we built a decoder to detect the transition between event-related desynchronization and event-related synchronization. Features for this decoder were correlates of motor termination in the upper μ and β bands. Results: The decoder reached an accuracy of 76.2% (N = 9), revealing the high robustness of our approach. More importantly, this paper shows that the decoding of motor termination has an intrinsic latency mainly due to the delayed appearance of its correlates. Because the latency was consistent and thus predictable, users were able to compensate it after training. Conclusion: Using our decoding system, BMI users were able to adapt their behavior and modulate their sensorimotor rhythm to stop the device (clock) accurately on time. Significance: These results show the importance of closed-loop evaluations of BMI decoders and open new possibilities for BMI control using decoding of movement termination.
Oral Ibrexafungerp: an investigational agent for the treatment of vulvovaginal candidiasis

ABSTRACT Introduction Vulvovaginal candidiasis (VVC) is a common fungal infection caused by predominantly Candida albicans, and is diagnosed in up to 40% of women with vaginal complaints in the primary care setting. Approximately 75% of women experience at least one episode during their reproductive years. Areas covered Ibrexafungerp is an orally active, semi-synthetic triterpenoid glucan synthase inhibitor under development for treatment and prevention of VVC. We present the chemistry, mechanism of action, pharmacology, microbiology, and results from clinical studies with ibrexafungerp in women with VVC. Expert opinion Ibrexafungerp addresses several unmet needs with existing antifungal drugs as a first in a new class of antifungal agents with a novel mechanism of action demonstrating no antifungal cross resistance with azoles, and fungicidal activity against Candida spp. , including fluconazole-resistant species. Some of the key attributes of ibrexafungerp related to VVC include oral one-day dosing, high tissue penetration, enhanced activity at low pH seen in the vagina, low risk for clinically significant drug–drug interactions, and a low risk of adverse events. If approved, ibrexafungerp will be the first new antifungal agent available for the treatment of VVC in more than 20 years and the only oral, non-azole antifungal approved for women suffering from VVC.