Miracle-dz/UniFAR-FTUs huggingface dataset:
Why is so little marketing research on Latin America published in high quality journals and what can we do about it

Purpose – First, this paper aims to uncover how much marketing research based on data gathered in Latin America has been published in high quality business and marketing academic journals over the past decade. Second, it seeks to present recommendations on best practice in conducting and publishing such research derived from a Delphi study of authors who succeeded in doing so.Design/methodology/approach – The paper undertakes a systematic review of the literature to identify the relevant published papers coupled with a Delphi study of the authors of those papers.Findings – Over the last decade only 22 papers were published in high quality journals in the marketing area based on data gathered in Latin America. The reasons for this scarcity explored in the Delphi study derive both from the way in which high quality journals operate as well as from how authors conducting research in that area of the world design their studies and subsequently present them in manuscripts submitted to journals. Key recommendat.
An Experimental System for Comparing Speed, Accuracy, and Completeness of Physician Data Entry using Electronic and Paper Methods

Electronic medical record (EMR) systems have important potential advantages over traditional paper-based systems, but they require that physicians assume responsibility for data entry. However, little is known about the quality of physician data entry in electronic systems. This study describes a system for comparing the speed, accuracy, and completeness of examination data entry using electronic and paper methods. Data will be shown to demonstrate that this may be a simple, reproducible, and useful technique.
Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis

Objective: We describe a novel congenital motor neuron disease with early demise due to respiratory insufficiency with clinical overlap with spinal muscular atrophy with respiratory distress (SMARD) type 1 but lacking a mutation in the IGHMBP2 gene. Methods: Exome sequencing was used to identify a de novo mutation in the LAS1L gene in the proband. Pathogenicity of the mutation was validated using a zebrafish model by morpholino-mediated knockdown of las1l. Results: We identified a de novo mutation in the X-linked LAS1L gene in the proband (p.S477N). The mutation is in a highly conserved region of the LAS1L gene predicted to be deleterious by bioinformatic analysis. Morpholino-based knockdown of las1l, the orthologous gene in zebrafish, results in early lethality and disruption of muscle and peripheral nerve architecture. Coinjection of wild-type but not mutant human RNA results in partial rescue of the phenotype. Conclusion: We report a patient with a SMARD phenotype due to a mutation in LAS1L, a gene important in coordinating processing of the 45S pre-rRNA and maturation of the large 60S ribosomal subunit. Similarly, the IGHMB2 gene associated with SMARD type 1 has been suggested to have an important role in ribosomal biogenesis from its role in processing the 45S pre-rRNA. We propose that disruption of ribosomal maturation may be a common pathogenic mechanism linking SMARD phenotypes caused by both IGHMBP2 and LAS1L.
MgCHA particles dispersion in porous PCL scaffolds: in vitro mineralization and in vivo bone formation

In this work, we focus on the in vitro and in vivo response of composite scaffolds obtained by incorporating Mg,CO3‐doped hydroxyapatite (HA) particles in poly(ε‐caprolactone) (PCL) porous matrices. After a complete analysis of chemical and physical properties of synthesized particles (i.e. SEM/EDS, DSC, XRD and FTIR), we demonstrate that the Mg,CO3 doping influences the surface wettability with implications upon cell–material interaction and new bone formation mechanisms. In particular, ion substitution in apatite crystals positively influences the early in vitro cellular response of human mesenchymal stem cells (hMSCs), i.e. adhesion and proliferation, and promotes an extensive mineralization of the scaffold in osteogenic medium, thus conforming to a more faithful reproduction of the native bone environment than undoped HA particles, used as control in PCL matrices. Furthermore, we demonstrate that Mg,CO3‐doped HA in PCL scaffolds support the in vivo cellular response by inducing neo‐bone formation as early as 2 months post‐implantation, and abundant mature bone tissue at the sixth month, with a lamellar structure and completely formed bone marrow. Together, these results indicate that Mg2+ and CO32– ion substitution in HA particles enhances the scaffold properties, providing the right chemical signals to combine with morphological requirements (i.e. pore size, shape and interconnectivity) to drive osteogenic response in scaffold‐aided bone regeneration. Copyright © 2012 John Wiley & Sons, Ltd.
Bosentan reduces blood pressure and the target-organ damage induced by a high-fructose diet in rats.

BACKGROUND Rats fed a high-fructose diet develop hyperinsulinaemia, hypertriglyceridaemia, hypertension, renal changes similar to those in diabetic rats and left ventricular hypertrophy with deposition of collagen. Bosentan is an antagonist of endothelin receptors. Other authors have demonstrated that bosentan is effective in preventing the increase in blood pressure induced by a high-fructose diet but, until now, the effect of the drug on the target organs has not been investigated. OBJECTIVE To evaluate whether bosentan is effective, not only in reducing blood pressure, but also in limiting the renal and cardiac changes induced by a high-fructose diet METHODS Forty Wistar-Kyoto (WKY) male rats were divided into four groups: groups 1 and 2 received a high-fructose diet, groups 3 and 4 received a standard diet for 1 month. Thereafter, the following treatments were administered: group 1, high-fructose diet plus bosentan 100 mg/kg per day; group 2, high-fructose diet plus placebo; group 3, standard diet plus bosentan 100 mg/kg per day; group 4, standard diet plus placebo. After a further 1 month, all animals were killed. A morphometric analysis was performed by examining 100 glomeruli for each animal. Renal deposits of collagen and fibronectin and cardiac deposits of collagen III were measured by means of immunochemistry. RESULTS By the end of the study, bosentan had completely reversed the increase in blood pressure induced by a high-fructose diet, without modifying the blood pressure in normotensive rats. Moreover, bosentan reduced glomerular hypertrophy and deposits of collagen and fibronectin in the kidney and cardiac deposits of collagen III. CONCLUSIONS The results of this study demonstrate that bosentan not only normalizes blood pressure, but also protects target organs in rats receiving a high-fructose diet.
Strong electronic correlation in the hydrogen chain: A variational Monte Carlo study

This work has been performed under the HPC-EUROPA2 project (Project No. HPC08TH6KD) with the support of the European Commission - Capacities Area - Research Infrastructures and using HPC resources from GENCI-IDRIS (Project No. 100063). We acknowledge also financial support from the Spanish MEC (Grant No. FIS2011-65702-C02-01), ACI-Promociona (Grant No. ACI2009-1036), Grupos Consolidados UPV/EHU del Gobierno Vasco (Grant No. IT-319-07), and the European Research Council Advanced GrantDYNamo (ERC-2010-AdG Proposal No. 267374).
The use of the Impact on Sibling scale with families of children with chronic illness and developmental disability.

OBJECTIVE This study evaluated the Impact on Sibling scale, a six-item measure of parents' perception of the effects of a child's illness on healthy siblings. METHODS Participants were 122 parents of a child with chronic illness, developmental disability, or autism spectrum disorder, and a well sibling aged 4-13 years. Parents completed the Impact on Sibling scale and the Child Behavior Checklist about the sibling, and completed the revised Impact on Family scale and the Brief Symptom Inventory about themselves. RESULTS The Impact on Sibling score was correlated with measures of sibling, parent and family functioning. The internal consistency of the Impact on Sibling scale was higher for families with children with chronic illness compared with the other two diagnostic groups. CONCLUSION The Impact on Sibling scale is a brief set of items that can help identify siblings who are negatively affected by a brother/sister's illness. Findings support further research on the Impact on Sibling scale, particularly with families of children with chronic illnesses.
Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats

The objective of the present study was to investigate the effect of Turmeric (Curcuma Longa) and Black cumin seed (Nigella Sativa) mixture on selected biochemical parameters of streptozotocin (STZ) induced diabetic rats. Therefore, twenty one healthy adult albino rats divided into three groups (7 rats in each). Rats of first and second groups were non diabetic and diabetic respectively. Rats of the third group were diabetic and received a mixture of Turmeric (0.5 g/kg b .wt.) and Black cumin seed (1 g/kg b.wt.). All treatments were orally administered by intragastric intubations once a day for six weeks. The changes in blood glucose level, body weight and water and food intake were measured. In addition, selected biochemical parameters were also determined. The present study revealed that, dietary supplementation of plant mixture of Turmeric and Black cumin seed to diabetic rats significantly (P
Information Technology and Value Creation

Information Technology (IT) has revolutionized the way business is done around the world. But the question remains, who benefits from IT? Does using IT create value for an organization? The answers discussed include the idea that it is the consumer who gains the most. Also, even if IT does not create value, attempting to do business without leveraging IT will result in serious setbacks, which make IT not an optional component of business. And whether one interprets the results of IT as advantages or disadvantages for society, the option of going back to a world without computers really does not exist.
Sugar-Regulated Expression of a Putative Hexose Transport Gene in Grape1

Different lengths of the promoter of grape (Vitis vinifera) VvHT1 (Hexose Transporter 1) gene, which encodes a putative hexose transporter expressed during the ripening of grape, have been transcriptionally fused to the β-glucuronidase reporter gene. In transgenic tobacco (Nicotiana tabacum) transformed with these constructs,VvHT1 promoters were clearly responsible for the sink organ preferential expression. The potential sugar effectors ofVvHT1 promoter were studied in tobacco cv Bright-Yellow 2 cells transformed with chimeric constructs. Glucose (56 mm), sucrose (Suc; 58 mm), and the non-transported Suc isomer palatinose doubled the β-glucuronidase activity conferred by the VvHT1 promoter, whereas fructose did not affect it. These effects were the strongest with the 2.4-kb promoter, which contains all putative sugar-responsive elements (activating and repressing), but they were also significant with the 0.3-kb promoter, which contains only activating sugar boxes. The induction of VvHT1 expression by both Suc and palatinose was confirmed in the homologous grape berry cell culture. The data provide the first example of a putative sugar transporter, which is induced by both glucose and Suc in higher plants. Although induction ofVvHT1 expression by Suc does not require transport, the presence of glucosyl moiety is necessary for Suc sensing. These results provide new insights into sugar sensing and signaling in plants.
Privacy and the New Energy Infrastructure

This article examines the privacy consequences of the diffusion of smart grid and smart metering technologies. It illustrates how high resolution electricity usage information can be used to reconstruct many intimate details of a consumer's daily life, and provides examples of how that information could be used in ways potentially invasive of an individual's privacy. The article then examines the nature of existing protections for such information, and evaluates their adequacy in protecting against some of these potentially invasive uses. The article concludes that state legislators and public utility commissions should examine the codes of conduct governing utility disclosure of consumer information in their various jurisdictions to address this new privacy threat.
CHANGES IN RETAIL FOOD DELIVERY: SIGNALS FOR PRODUCERS, PROCESSORS AND DISTRIBUTORS

This paper contains two chapters related to changes in retail food delivery and sales. The first discusses trends in consumer demographics and lifestyles and how these continue to drive changes in the way food is prepared and delivered to consumers. Retail stores are responding with new formats: providing more ready to eat foods; more convenient store layouts; lower prices and better service in niche markets across the country. Their demands send signals up the food chain to processors and producers that alter their production and inventory decisions. Electronic information technology speeds these changes and leads to more efficient operation with, allegedly, better service for consumers. The second chapter discusses how advances in information technology affect not only the internal business operations in food firms throughout the food supply chain but also how the product flows and how businesses link their processes together. The reengineering of the food supply chain by way of an industry-wide initiative called "efficient consumer response" (ECR) is explained and analyzed for its motivations and implementation, thus far. The many facets of ECR such as product replenishment and promotion are discussed. Lessons learned from ECR include that it is possible to accommodate the coexistence of firms of various sizes and types, and that the role of trade associations in facilitating industry-wide changes is vital and impressive.
Value Investing: New Strategies for Stock Market Success

A VALUE PERSPECTIVE: A Realistic Approach to the Stock Market Cycles of Stock Market Value A VALUE APPROACH TO MARKET TIMING: Understanding Interest Rates Interest Rates and Stock Market Value A Framework for Market Timing A VALUE APPROACH TO STOCK SELECTION: Asset Value Analysis Earnings Value Analysis Winning Stock Investments THE STRATEGIC VALUE INVESTOR: Identifying Important Market Tops and Bottoms Mutual Fund Strategy Portfolio Strategy Appendices Bibliography Index.
Effect of maternal food restriction on circulating insulin and glucagon levels and on liver insulin and glucagon binding sites of fetal and suckling rats.

Food was restricted in pregnant and nursing rats in order to evaluate the effect of malnutrition on insulin and glucagon metabolism in fetal and suckling rats. Food restriction of the mothers induced a loss of body and liver weights in their offspring, which was more pronounced in suckling than in fetal rats. A significant decrease of circulating insulin and glucagon levels in fetal and suckling rats from food restricted mothers (FRM) was also observed. In liver membranes insulin binding was higher in control, fetal and suckling rats than in adult animals, but maternal food restriction decreased insulin binding to liver membranes of suckling rats, and no changes between control and fetuses from FRM were observed. By contrast, glucagon binding was higher in adult than in younger control animals; however maternal food restriction had no effect on glucagon binding to liver membranes of fetal rats, although they produced an increase in 10 day-old suckling rats. The modifications in insulin and glucagon binding reflect changes in the number of receptors, but not in the affinity constants. The time courses of insulin and glucagon association to liver membranes were unaffected by the development or by the nutritional status of the animals. Degradation of insulin and glucagon by liver membranes was significantly lower in young rats and in rats from FRM, but this does not seem to be responsible for the differences observed in binding. No significant differences in the degradation of insulin and glucagon receptors between different groups of liver membranes were found. (ABSTRACT TRUNCATED AT 250 WORDS)
Haematological findings in chronic alcoholics after heavy drinking with special reference to haemolysis

Abstract. Haematological abnormalities are frequently found in heavy‐drinking chronic alcoholics, but anaemia is generally a rare complication. When present, haemolysis is considered to be one of the most common causes. However, little is known about mild haemolysis without anaemia. The present report on eighteen male chronic alcoholics with a recent heavy debauche but without signs of severe liver disease gave support for the occurrence of a reversible low‐degree haemolysis without concomitant gross changes of the erythrocytes. Thus the bone marrow showed an increased erythropoiesis in the absence of iron deficiency and known blood losses. Further, increased reticulocyte counts and low levels of haemopexin were noted in the early abstinence. Finally, during the withdrawal phase haptoglobin and haemopexin increased concomitantly with diminishing values of unconjugated bilirubin. The most likely cause of the proposed diminished red cell survival before the withdrawal is supposed to be a reduced membrane stability.
Factors influencing long‐term outcome after kidney transplantation

Many factors influence the long‐term outcome of kidney transplantation, which is defined very schematically by patient death or renal dysfunction leading to graft loss. The most important of these factors is most likely the quality of the transplant itself, with kidneys from living donors showing a positive impact, while kidneys from expanded criteria donors show deleterious impacts. Various clinicopathological scores exist to predict mid‐ to long‐term outcomes and avoid the transplantation of kidneys displaying inferior results. The key factors related to the recipient include their age as well as disease recurrence, HLA matching, HLA immunization, ethnic background, time on dialysis, and cardiovascular comorbidities. Renal function, defined based on estimated GFR and/or proteinuria values, is a result of all these factors. Delayed graft function has a detrimental long‐term impact, as does the level of renal function impairment either in stable condition or in case of progressing dysfunction. Finally, although current immunosuppression regimes are highly efficient in preventing acute rejection, the burden of specific (diabetes, nephrotoxicity) and nonspecific (infection and cancer) side effects has significant negative long‐term consequences that may well be worse in the future because of the increasing ages of both donors and recipients. The development of safer immunosuppression strategies is therefore crucial to improve long‐term outcomes.
Imaging of pelvic injuries in athletes.

The pelvis is a complex osseous anatomical region providing the origin and insertion for a number of powerful muscle groups. It performs a pivotal role in all athletic activities and forces exceeding six to eight times body weight traverse this region during even light exercise making the pelvis particularly prone to sporting injury. The clinical features of injury within the pelvis can be non-specific and a number of diagnoses need to be considered. The location and pattern of injury depends on the sporting activity, the maturity of the athlete and whether the injury sustained is part of an acute or chronic (overuse) process. Recovery from pelvic injury can be prolonged especially if the initial diagnosis is incorrect and appropriate treatment delayed. This article will review the spectrum of pelvic sports injuries and the imaging strategies that can be employed to diagnose and grade such injuries.
Recovery, Psychomotor Skills, and Simulated Driving after Brief Inhalational Anesthesia with Halothane or Enflurane Combined with Nitrous Oxide and Oxygen

Recovery from anesthesia was assessed in a controlled manner in 34 healthy student volunteers, using a psychomotor test battery 1 and 5 hours and a driving simulator 2, 4.5, and 7 hours after 3.5 minutes of anesthesia with halothane or enflurane combined with nitrous oxide and oxygen. Psychomotor performances remained significantly (P < 0.05 to P < 0.001) worse than in an unanesthetized control group for 5 hours after both halothane and enflurane. However, impairment of driving skills 4.5 hours after anesthesia was measurable only after halothane (P < 0.05). It is concluded that after even brief periods of halothane or enflurane anesthesia patients should not drive or operate machinery for at least 7 hours. The magnitudes and durations of the residual effects of both agents on psychomotor performance were, however, less than those previously found after thiopental, methohexital, or diazepam.
CHEMICALLY MODIFIED TETRACYCLINE (COL-3) IMPROVES SURVIVAL IF GIVEN 12 BUT NOT 24 HOURS AFTER CECAL LIGATION AND PUNCTURE

ABSTRACT Sepsis can result in excessive and maladaptive inflammation that is responsible for more than 215,00 deaths per year in the United State alone. Current strategies for reducing the morbidity and mortality associated with sepsis rely on treatment of the syndrome rather than prophylaxis. We have been investigating a modified tetracycline, COL-3, which can be given prophylactically to patients at high risk for developing sepsis. Our group has shown that COL-3 is very effect at preventing the sequelae of sepsis if given before or immediately after injury in both rat and porcine sepsis models. In this study, we wanted to determine the "treatment window" for COL-3 after injury at which it remains protective. Sepsis was induced by cecal ligation and puncture (CLP). Rats were anesthetized and placed into five groups: CLP (n = 20) = CLP without COL-3, sham (n = 5) = surgery without CLP or COL-3, COL3@6h (n = 10) = COL-3 given by gavage 6 h after CLP, COL3@12h (n = 10) = COL-3 given by gavage 12 h after CLP, and COL3@24h (n = 20) = COL-3 given by gavage 24 h after CLP. COL-3 that was given at 6 and 12 h after CLP significantly improved survival as compared with the CLP and the CLP@24h groups. Improved survival was associated with a significant improvement in lung pathology assessed morphologically. These data suggest that COL-3 can be given up to 12 h after trauma and remain effective.
An Improved Super-resolution Image Reconstruction Algorithm

The paper introduces the Keren registration method and points out its disadvantage which means it will become inaccuracy on the large scale parameters. To reduce the error on large scale parameters of Keren registration, a two step method is proposed, which the phase correlation algorithm is used to estimate the large translation and rotation angle roughly and the improved Keren algorithm is used to estimate accurately the small translation and rotation angle. The experimental results show that the two step method makes less absolute error of angle than Keren method in the situation of large translation and rotation angle. A new method of estimating the standard deviation of noise is introduced to the robust certainty function, which reduces the impact of noise in the process of interpolation using normalized convolution algorithm. By the edge detection of fusion image in the first stage of the interpolation process of normalized convolution algorithm, a calculation method of long axis and short axis of the structure self-adaptive function is improved. The experimental results show that the proposed interpolation method can improve the performance of the original algorithm and enhance the effect of image super-resolution reconstruction.