Miracle-dz/UniFAR-FTUs huggingface dataset:
Microbial lectins and agglutinins : properties and biological activity

Introduction to Microbial Lectins and Agglutinins Viruses as Hemagglutinins and Lectins Mannose Specific Bacterial Surface Lectins Glycolipids as Receptors for Escherichia coli Lectins or Adhesions Genetics and Biogenesis of Escherichia coli Adhesions Structure-function Analysis of Gonococcal Pili Adhesions Structure-function Analysis of Gonococcal Pili Adhesions of Vibrio cholerae Fimbrial Lectins of the Oral Actinomyces Myxobacterial Hemagglutinin: A Developmentally Induced Lectin from Myxococcus xanthus Mycoplasmal Adhesions and Lectins Fimbriae, Lectins, and Agglutinins of Nitrogen-fixing Bacteria Lectins of Pseudomonas aeruginosa: Properties, Biological Effects, and Applications Sugar Binding Bacterial Toxins Lectins and Agglutinins in Protozoa Lectins in Etnamoeba histolytica Carbohydrate Recognitions Mediate Attachment of Plasmodium falciparum Malaria to Erythrocytes Lectins from the Cellular Slime Molds Fungal Lectins and Agglutinins The Function of Lectins in Interactions Among Marine Bacteria, Invertebrates, and Algae
Cenozoic deformation in the Tauern Window (Eastern Alps) constrained by in situ Th-Pb dating of fissure monazite

Abstract. Thorium–lead (Th-Pb) crystallization ages of hydrothermal monazites from the western, central and eastern Tauern Window provide new insights into Cenozoic tectonic evolution of the Tauern metamorphic dome. Growth domain crystallization ages range from 21.7 ± 0.4 to 10.0 ± 0.2 Ma. Three major periods of monazite growth are recorded between ∼ 22–20 (peak at 21 Ma), 19–15 (major peak at 17 Ma) and 14–10 Ma (major peak around 12 Ma), respectively, interpreted to be related to prevailing N–S shortening, in association with E–W extension, beginning strike-slip movements and reactivation of strike-slip faulting. Fissure monazite ages largely overlap with zircon and apatite fission track data. Besides tracking the thermal evolution of the Tauern dome, monazite dates reflect episodic tectonic movement along major shear zones that took place during the formation of the dome. Geochronological and structural data from the Pfitschtal area in the western Tauern Window show the existence of two cleft generations separated in time by 4 Ma and related to strike-slip to oblique-slip faulting. Moreover, these two phases overprint earlier phases of fissure formation. Highlights. In situ dating of hydrothermal monazite-(Ce). New constraints on the exhumation of the Tauern metamorphic dome. Distinct tectonic pulses recorded from east to west.
Standardized maximin criterion for discrimination and parameter estimation of nested models

Abstract A new criterion for approximate designs called the standardized maximin criterion suited for both model discrimination and parameter estimation based on D- and Ds -optimality criteria is introduced and studied. It is proved that the computation of an experimental design which is optimal with respect to this criterion can be reduced to the computation of multiple experimental designs which are optimal with respect to the simpler weighted criterion. Several numerical examples that describe the efficiency of the proposed criterion are provided.
Thermal Performance of Oscillating Blade with Various Geometries in a Straight Channel

In this study, the effect of stationary and oscillating blades on the forced convection heat transfer in a channel are studied numerically. Simulations are performed in a fully-developed, laminar, unsteady, and incompressible flow with Reynolds number and Prandtl number equal to 100 and 1, respectively. The effects of blade geometry, oscillating speed and oscillation angle on heat transfer and pressure drop are studied. The results are presented in terms of time averaged Nusselt number, temperature and vorticity distribution and the pressure drop. The results indicate that the oscillation angle and oscillating speed of the blade and the number of the blades, affect the thermal performance of the channel. For most cases, it was observed that the effect of the oscillation angle is more than that for the oscillating speed on heat transfer enhancement. However, increasing the number of blades does not necessarily help to enhance the heat transfer, but it can slightly decrease the pressure drop.
NOVELTIES IN BRAZILIAN BEGONIACEAE II: a new species from Minas Gerais

Begonia vasconselosiana, a new species of Begonia from Minas Gerais state, Brazil is described. Begonia vasconselosiana is morphologically similar to Begonia lealii Brade with which it is compared. The new species grows in campos rupestres in Atlantic Forest, east of Minas Gerais state, Brazil. Description, diagnosis, etymology, taxonomic comments, illustrations, and conservation status of the new species are provided.
Redox Characterization of Proteins Involved in the Mitochondrial Intermembrane Space Pathway

Author(s): Neal, Sonya Elina | Advisor(s): Koehler, Carla M | Abstract: A redox-regulated import pathway consisting of Mia40 and Erv1 was identified to mediate the import of cysteine-rich proteins into the mitochondrial intermembrane space. Mia40 mediates the import and oxidative folding of substrates and Erv1 is a putative oxidant for Mia40. The mechanism involved in the oxidation of substrates and subsequent release from Mia40 is not clear. In this study, we have reconstituted the disulfide exchange reaction in vitro using Tim13 as the substrate. By reconstituting the Mia40-Erv1 import pathway with cysteine mutants of Tim13, we were able to determine that C57, C61 and C73 are required for oxidative folding by Mia40. Moreover, we show that Tim13 is able to induce a conformational change and reduce 6 cysteines in Mia40. Finally, in organello studies confirmed that in yeast strains deficient in Erv1, Mia40 remains in a reduced state. In all, these experiments suggest that Mia40 is able to act as an electron sink in which it accumulates electrons in the presence of Tim13. Subsequently, the Mia40-Erv1 import pathway has electron acceptors to continue the process of disulfide bond formation. The aerobic electron acceptors include oxygen and cytochrome c, but an anaerobic acceptor has not been identified. Here we show that the fumarate reductase Osm1, which transfers electrons from fumarate to generate succinate, fills this gap as a new electron acceptor. In addition to microsomes, Osm1 localizes to the IMS and assembles with Erv1 in a complex. In reconstitution studies, Erv1 transfers electrons to Osm1 in the oxidation of Tim13. Comparative assays support that Osm1 accepts electrons with similar efficiency as cytochrome c and that the cell has strategies to coordinate expression of the terminal electron acceptors. Thus, Osm1 is a new terminal electron acceptor in the IMS that may also have a similar function in the endoplasmic reticulum.
Effect of Pillar Ripple on Static and Dynamic Trade-Offs in Superjunction MOSFETs

Multi-epitaxially grown superjunctions feature a fluctuation of the doping concentration (ripple) in the pillars and the ripple is highly dependent on the supplied thermal energy during the fabrication. This study thoroughly investigates the relationship between the ripple in the pillars and the static/dynamic characteristics of the device. The ripple dependent trade-offs in terms of the specific resistance and turn-off switching loss will be able to provide a guide for developing fine pitch superjunction devices.
Modeling the Natural Convection Flow in a Square Porous Enclosure Filled with a Micropolar Nanofluid under Magnetohydrodynamic Conditions

The laminar, natural convective flow of a micropolar nanofluid in the presence of a magnetic field in a square porous enclosure was studied. The micropolar nanofluid is considered to be an electrically conductive fluid. The governing equations of the flow problem are the conservation of mass, energy, and linear momentum, as well as the angular momentum and the induction equations. In the proposed model, the Darcy–Brinkman momentum equations with buoyancy and advective inertia are used. Experimentally obtained forms of the dynamic viscosity, the thermal conductivity, and the electric conductivity are employed. A meshless point collocation method has been applied to numerically solve the flow and transport equations in their vorticity-stream function formulation. The effects of characteristic dimensionless parameters, such as the Rayleigh and Hartmann numbers, for a range of porosity and solid volume fraction of Al2O3 particles in a water-based micropolar nanofluid on the flow and heat transfer in the cavity are investigated. The results indicate that the intensity of the magnetic field significantly affects both the flow and the temperature distributions. Moreover, the addition of nanoparticles deteriorates the heat-transfer efficiency under specific conditions.
Assessment of genetic variation in the threatened New Zealand sea lion, Phocarctos hookeri, and its association with fitness

The New Zealand sea lion (NZSL) is an interesting model of disease resistance or susceptibility, in that it has experienced a prolonged small population size and exists in relative isolation. It is a species of high conservation significance, due to its small and declining population size. A reduction in population size is often followed by increased inbreeding and a loss of genetic variation which can lead to reduced future evolutionary potential of the species. Additionally, it can also render the species less able to respond to new pathogens in the population with serious consequences for reproduction and survival. Allelic richness at microsatellite loci can provide a good estimation of evolutionary potential. We used 21 microsatellite loci, previously shown to have broad utility in pinnipeds, to determine population-wide levels of variation in the threated NZSL, and we present locusand population-specific statistics for these microsatellite loci in the NZSL. Average allelic diversity is 9.3 (range 4 – 20 alleles per locus) with an observed (HO) and expected (HE) of 0.67 and 0.64 respectively. However allelic diversity reduces to 4.14 – 7.33 when the population is considered as separate breeding seasons and status groups (dead pups, live pups, live adult females and live adult males). One locus appeared to deviate from Hardy-Weinberg equilibrium which is a consequence of the nature of allelic diversity at this locus; however we do not detect the presence of null alleles at these loci. Three loci were prone to genotyping error and resulted in a high average error rate for microsatellite genotyping of 1.95%, which reduced to 0.67% upon removal of these loci. Analyses with the program Bottleneck provides statistical evidence for a recent population size reduction, which was significant under both the infinite alleles model and the two-phase model of microsatellite mutation. Finally, we provide a measure of Fis that is suggestive of inbreeding/non-random mating evident in dead pups, live adult females and live adult males the NZSL population at Sandy Bay, consistent
A Comparative Assessment of Pig Manure and Poultry Manure in the Biodegradation of Diesel Contaminated Soil

Aim: This research aims to carry out a comparative assessment on the use of pig manure and poultry manure as a carbon substrate for the degradation of diesel. Study Design: Fifteen experimental pots were used in this analysis and this was carried out for a duration of 44 days. This experiment was done in stages and each stage was for 2 weeks. Experimental pots were labelled appropriately with the right concentrations of soil, diesel oil and manure to avoid cross-contamination. This experiment involved one pollution level of 0.275% of the weight of soil. Two (2) treatment concentrations of 20% and 40% of the weight of soil for pig manure and poultry manure respectively, three temperature levels of 25oC, 30oC, 37oC. Place and Duration of Study: Microbiological laboratory and Environmental Science laboratory of Coventry University/two months. Original Research Article Njunbemere et al.; JENRR, 4(3): 1-13, 2020; Article no.JENRR. 54527 2 Methodology: Bioremediation of the diesel contaminated soil involved two concentration levels of 40 g and 80 g. These concentrations (40 g and 80 g) were used for both pig manure and poultry manure. These manures were measured in the fume cupboard using an electronic balance to avoid pollution to air. The right manure concentrations of 40 g and 80 g were transferred into the appropriately labelled pots containing 200 g of soil each. The mixture (soil+ diesel+ pig/poultry manure) was properly homogenised and allowed for biodegradation. Results: Results of TPH analysis showed high percent removal of 84.71%, 90%, 82.35%, 85.29% for soil treated with pig manure at 40 g and 80 g, and soil treated with 40 g, 80 g of poultry manure at 37oC. This study showed that the microbial consortium, nutrient concentration and temperatures played great roles in enhancing bioremediation process. Conclusion: Nutrient addition enhanced the degradation of diesel contaminated soil. It is evident from the results that at 37oC diesel degradation occurred more in all soil samples than at 30 o C and 25oC. Therefore, it can be concluded that 37oC is most suitable for diesel degradation with the highest efficiency in soil treated with 80 g of pig manure. However, at 25 o C, high percent degradation also occurred in all treated samples with spi-40 g having the highest percent degradation.
A Velocity Algorithm for Nonlinear Model Predictive Control

This brief presents a velocity-form nonlinear model predictive control (NMPC) scheme via velocity-based linearization. The main features of this approach are built-in offset-free control in the presence of disturbances, tracking of piecewise constant, possibly unreachable, reference signals, and simple implementation, as a parameterization of all equilibria is not necessary. Furthermore, the model in velocity form can be expressed as a quasi-linear parameter-varying (quasi-LPV) model, for which efficient online optimization algorithms exist. The proposed approach is experimentally validated on a 2-degree-of-freedom robotic manipulator, where its capabilities and efficiency are highlighted.
Influence of Supply Chain Collaborative Innovation on Sustainable Development of Supply Chain: A Study on Chinese Enterprises

The recent trade friction between the two largest economies, US and China, is having a profound impact on the sustainable development of supply chains at a global scale. Supply chain collaborative innovation has not only become the main means for enterprises in various countries to cope with imponderable changes, but also been the driver of increasing supply chain dynamic capability and of achieving sustainable development of supply chains. Based on the survey data of 510 Chinese enterprises, this paper adopts the hierarchical regression analysis and a structural equation model to study the impact of supply chain collaborative innovation on the sustainable development of supply chains. The results show that: (1) Three modes of supply chain collaborative innovation (namely, technology collaborative innovation, management collaborative innovation, and market collaborative innovation) have different effects on supply chain dynamic capability and sustainable supply chain performance. (2) Supply chain dynamic capability plays a significant intermediary role between supply chain collaborative innovation and sustainable supply chain performance. (3) Supply chain technology collaborative innovation has the greatest direct impact on sustainable supply chain performance, followed by supply chain management collaborative innovation. However, the direct effect of supply chain market collaborative innovation on sustainable supply chain performance is not significant; under the intermediary role of dynamic capability, supply chain market collaborative innovation has a significant indirect effect on sustainable supply chain performance.
Factors Contributing to Mobile Phone Dependence Amongst Young People—Educational Implications

The use of mobile devices facilitates access to knowledge and is at the base of the education of the future. Although the digital society has contributed a number of benefits, it has also been associated with worrying behaviors. The study design consisted of a quantitative approach that was descriptive, inferential and ex post facto in nature. Its purpose was to better understand the opinion of young people regarding smartphone use and describe dependence deriving from regular use. The sample was formed of 420 students from the Faculty of Education at the University of Granada. Results indicate that mobile phone use has displaced use of other technologies such as the television and is associated with communication and recreational activities. In addition, a profile was identified for young people at greater risk of developing a dependence on their mobile devices. This profile constituted female smartphone users with recreational motives and individuals who exceeded mobile phone use by more than six hours a day. To improve the educational use of smartphones, prevention and intervention plans must be designed which ensure correct management of this device, taking advantage of the benefits they offer, while avoiding problems derived from inappropriate use.
HI-Sky: Hash Index-Based Skyline Query Processing

The skyline query has recently attracted a considerable amount of research interest in several fields. The query conducts computations using the domination test, where “domination” means that a data point does not have a worse value than others in any dimension, and has a better value in at least one dimension. Therefore, the skyline query can be used to construct efficient queries based on data from a variety of fields. However, when the number of dimensions or the amount of data increases, naïve skyline queries lead to a degradation in overall performance owing to the higher cost of comparisons among data. Several methods using index structures have been proposed to solve this problem but have not improved the performance of skyline queries because their indices are heavily influenced by the dimensionality and data amount. Therefore, in this study, we propose HI-Sky, a method that can perform quick skyline computations by using the hash index to overcome the above shortcomings. HI-Sky effectively manages data through the hash index and significantly improves performance by effectively eliminating unnecessary data comparisons when computing the skyline. We provide the theoretical background for HI-Sky and verify its improvement in skyline query performance through comparisons with prevalent methods.
A Navigation and Pressure Monitoring System Toward Autonomous Wireless Capsule Endoscopy

Continuous navigation information for medical insertion methods including wireless capsule endoscopy is an important feature to guide a medical instrument/object to the targeted location within a hollow organ or internal cavity of the patient in the best possible way. Also, an autonomous medical insertion or swallowable device with a self-contained navigation system would reduce the role of the high-level operator and hence reduce the human-factor mistake and risk of injury. The navigation techniques suggested for Wireless Capsule Endoscopy are image-based that are required to transfer and process a significant amount of data in real-time operation. This would increase the complexity of the system and would be more difficult in dark or liquid environments. A novel navigation system for Wireless Capsule Endoscopy/ordinary endoscopy that does not depend on any external source for operation and can handle the uncertainties of the path even in a dark or liquid environment (i.e.mucosa) of the human body is presented in this paper. The key element of the system is based on a capacitive-based pressure sensor array mounted on the capsule with the shape of semi-hemisphere. The place of each node is arranged to represent the variation in the latitude and the longitude of the travelling path. The system can acquire the required information to navigate the capsule in three-dimensional space and enhance the safety of the locomotion by monitoring the pressure between the capsule and the ambient environment. The system determines the variation of the path 180° in longitude and latitude with less than (<0.004%) percentage of error. Working algorithms for flexible and rigid environments are described in this paper.
An Empirical Investigation on Foreign Capital Inflows and Economic Development in Nigeria

In an attempt to attained sustainable level of economic development in a nation, empirical studies as well as financial theories posit that foreign capital inflows play a lead role. As such, this study set out to empirically investigate the extent to which foreign capital flows promotes economic development in Nigeria. Time series data between the periods 1986 to 2018 were sourced from the central bank of Nigeria statistical bulletin and world bank data based. The study proxied foreign capital flows using foreign direct investment, foreign portfolio investment, foreign aids and external borrowings which is decomposed into multilateral and bilateral loans while Human development index is used as proxy for economic development. The study further employed unit root test, co-integration test, error correction model and granger causality test to ascertain the direction of relationship. Findings reveal that of the five indices of foreign capital inflows, three (foreign portfolio investment, foreign aids and bilateral loan) prove to be significant in promoting economic development in Nigeria, while foreign direct investment and multilateral loan are negatively related to economic development in Nigeria. As such, the study conclude that foreign capital inflows in the form of foreign portfolio investment, foreign aids and bilateral loans are significant in boosting economic development in Nigeria. Therefore, we recommend that managers of the Original Research Article Monogbe et al.; AJEBA, 14(2): 63-76, 2020; Article no.AJEBA. 54386 64 Nigerian economic should create an enabling financial environment as this will help in accelerating further inflows of portfolio investment and thus boost economic development in Nigeria.
Role of TRP Channels in Pain: An Overview

Despite the investment of signifi cant resources by the pharmaceutical industry to identify novel analgesic drugs, chronic pain, which is most commonly defi ned as pain lasting longer than 3 months (i.e., outlasting the usual healing process), still represents a diffi cult treatment challenge in a large sector of the population, consisting of an estimated 50 million Americans ( http:// www.painfoundation.org ). Patients suffering from disabling painful con ditions often need complex and aggressive treatment that combines medical and surgical approaches (Campbell et al., 2006 ; Gidal and Billington, 2006 ; Katz and Berkin, 2008 ). The mainstay of medical pain therapy remains drugs that have been around for decades, like nonsteroidal anti infl ammatory drugs (NSAIDs), or drugs that have been around even for centuries, such as opiates (Katz and Berkin, 2008 ). Many patients, however, fi nd that over the counter NSAID medications are ineffective for pain relief. Opiates are very powerful painkillers, but their clinical use is limited by adverse effects (Gallagher and Rosenthal, 2008 ). Also, many clinicians are concerned about the abuse of opiates ( http://www.opiates.com/prescription-painkillersaddiction.html ). Of the newer agents, the COX 2 inhibitor rofecoxib (sold by Merck under the brand name Vioxx) was withdrawn from the market over concerns of its cardiovascular side effects (Brophy, 2007 ), casting a large cloud over the 2