Miracle-dz/UniFAR-FTUs huggingface dataset:
ATENÇÃO ODONTOLÓGICA PARA IDOSOS: perfil e percepção do cuidador / ELDERLY DENTAL CARE: profile and perceptions of caregivers

Introducao. O numero de idosos aumenta de forma progressiva, bem como a necessidade de profissionais qualificados para cuidar desse contingente da populacao. Objetivo. Conhecer o perfil e a percepcao dos cuidadores sobre a atencao a saude bucal dos idosos. Metodos. Estudo descritivo com abordagem quantitativa, realizado na Instituicao de Longa Permanencia Solar do Outono, em Sao Luis-MA, no periodo de outubro a novembro de 2009, por meio de questionario aplicado com os cuidadores dos idosos da Instituicao. Resultados. Os resultados mostraram que 80% dos cuidadores sao do sexo feminino, 66,7% possuem nivel medio de ensino, com idade inferior a 40 anos (73,4%) e que 80% trabalham, como cuidador, entre 1 e 5 anos . Quanto a frequencia da higiene bucal nos idosos, 80% afirmaram ser importante a realizacao da mesma, todos os dias, embora a maioria dos idosos (60%) realize a higiene apenas uma vez ao dia. Para 40% dos cuidadores a tarefa de higiene bucal dos idosos e muito dificil. 66,67% informaram ser natural perder os dentes na velhice e importante a higiene bucal para a saude geral do idoso. Conclusoes. Diante dos resultados, observou-se que os cuidadores entrevistados reconhecem que a saude bucal interfere na saude geral dos idosos e que os cuidados com a higienizacao da cavidade oral deve ser diaria, embora os dados demonstrem que nao ha uma sistematizacao desta pratica. Palavras-chave: Cuidadores. Saude bucal. Idoso. Abstract Introduction. The number of elderly people increases progressively, as well as the necessity of qualified professionals to take care of this population. Objective. To know the profile and perception of caregivers about elders' oral health care. Methods. Descriptive study with quantitative approach which was performed at the Longa Permanencia Solar do Outono Institution in Sao Luis - MA, during October to November 2009. It was used a questionnaire that was applied to the elderly caregivers of the Institution. Results. The results showed that 80% of caregivers were female, 66.7% had high school, 73.4% were under 40 years of age and 80% have worked as caregivers for 1 to 5 years. Regarding the oral hygiene, 80% of the caregivers said it was important to perform it every day. However, most elderly (60%) perform the hygiene only once a day. 40% of caregivers said that the task of oral hygiene in the elderly is very difficult. 66.67% said that is natural to lose teeth in old age and that oral hygiene is important for overall health of the elderly. Conclusion. According to the results of this research, we could notice that the interviewees recognize that oral health influences the overall elderly health and that elders' dental care should be performed daily. However, the data obtained in this study show that there is not a systematic practice of dental care. Keywords: Caregivers. Oral hygien. Elderly.
PATTERNS OF FOREST LOSS PER TERRITORIAL CATEGORY IN THE AMAZON RAINFOREST: PERU (2001–2016)

The objective of the present study was to analyze the patterns of forest loss in the Peruvian Amazon between 2001 and 2016 according to 16 territorial categories and two types of land tenure (public and private) and administration (public and private). Through descriptive analysis and multivariate analysis using official forest loss data provided by the Peruvian government, a progressive increase in forest loss was detected over time, with the highest peaks in 2009, 2014, and 2016. The departments of San Martin, Loreto, and Ucayali presented the greatest loss. The three territorial categories with the greatest forest loss were the noncategorized areas (NCs), indigenous communities with land titles (ICTs), and rural lands (RLs). The NC category did not affect the general tendency of deforestation in Peru given that the forest loss dynamics in this category were similar to those of other territorial categories with assigned land rights.
Alignment of Cluster Complexity at Network Systems

This paper considers data management structures and cluster technologies in large-scale networks. Suboptimal network partitioning problems are formulated on the base of complexity index alignment. We propose methods for these problems solving, in particular the data clusters number and its boundaries determining. We describe a multi-stage iterative scheme for the semantic data mining from a large document with interdependent sections as well. At the first stage, a priori data mining complexity from these sections is estimated. Then we refine this complexity taking into account the revealed data mining from the adjacent sections. Based on this, the final partitioning of the data set of a big document into clusters is formed under circumstances of deadline and restrictions on financial resources. The proposed methods have been applied in some large-scale transport projects.
DISCOVERING THE MOLECULAR AND CELLULAR MECHANISMS UNDERLYING FENFLURAMINE-INDUCED CARDIOPULMONARY SIDE EFFECTS

G protein-coupled receptors (GPCRs) are plasma membrane proteins that act as sensors for extracellular stimuli (e.g., photons, neurohumoral moduluators, odorants and tastants, lipids). The cognate stimulus for a GPCR induces a conformational change that catalyzes, via heterotrimeric G proteins, a series of biochemical reactions inside the cell (i.e., a response); the responses can lead to phenomena such as differentiation, morphological changes, chemotaxis, and mitosis. G protein-coupled receptors are the targets of, in addition to endogenous neurohumoral molecules, more than 30% of currently marketed pharmaceutical drugs. For instance, the effective appetite suppressant fenfluramine reduces appetite via activation of serotonin (5-hydroxytryptamine, 5-HT) 2C (5-HT2C) receptors. Fenfluramine was, despite its efficacy as an anorexigen, withdrawn from market due to its association with life-threatening cardiovascular side effects [i.e., valvular heart disease (VHD) and pulmonary hypertension (PH)]. The work presented in this thesis describes efforts to identify the cellular and molecular mechanisms responsible for fenfluramine-induced VHD. Evidence is presented that both fenfluramine and, to a greater extent, its major in vivo metabolite norfenfluramine, activate mitogenic 5-HT2B receptors, which are expressed in human heart valve interstitial cells (VICs). Both fenfluramine and norfenfluramine induce mitogenic responses from VICs in vitro that are abrogated by a 5-HT2B receptor antagonist. Further, data implicating van der Waals (vdW) interactions between the -methyl group of S-(+)-norfenfluramine and a valine in the second transmembrane helix of the receptor (V2.53) in the compound s valvulopathic but not anorexigenic effects are described. The implication of the findings described herein on preventing drug-associated cardiopulmonary side effects and developing safe, effective anorexigens are also discussed.
TCRM_A_204860 803..810

1Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, People’s Republic of China; 2Department of Clinical Pharmacy, School of Pharmacy, Nanjing Medical University, Nanjing 211166, Jiangsu, People’s Republic of China; 3Department of Internal Medicine, The First Clinical Medical College, Nanjing Medical University, Nanjing, Jiangsu 210029, People’s Republic of China; 4Department of Pharmacy, Peking University Third Hospital, Beijing 100191, People’s Republic of China Purpose: This study aimed to evaluate Atorvastatin (ATO)-associated hepatotoxicity using
Perceives Ease of Use, Perceive Usefulness, and Behavioural Intention: the Acceptance of Crowdsourcing Platform by Using Technology Acceptance Model (TAM)

This study aims to identify the relationship between the acceptance of Crowdsourcing platform by using TAM model (Perceives Ease of Use, Perceive Usefulness, and Behavioral Intention). A survey questionnaire was designed as a research instrument to evaluate respondents and find out the relationship between perceive ease of use, perceive usefulness and behavioral intention. A total of 48 questionnaires were distributed via online among students of a business faculty from a public university in Kelantan. The data collected was analyzed using SPSS 21.0 and this study found that all the independent variable has significant positive relationship on behavioral intention. In addition, for all three variables which were perceive ease of use, perceive usefulness and behavioral intention, the result indicates that all variables reliability was high.
MECHANISMS AND ECONOMIC CONSEQUENCES OF PUBLIC INTERVENTION IN AGRICULTURAL HOLDINGS IN POLAND DURING THE PERIOD OF EU MEMBERSHIP

The concept of public intervention in agriculture can be understood very broadly,as any act or omission of the operation of public state institutions. The articlediscusses the economic reasons for the public intervention, then presents the typesand effects of intervention implemented by the CAP as well as the impact ofintervention policy on economic decisions of agricultural producers. In the furtherpart of the article, based on the statistic data from 2004-2016, were presented thechanges in agriculture sector. A characteristic feature of this process is thedeagrarisation the national economy and the development of rural areas.Throughout this process, it is extremely important for the ongoing structuralchanges to result in the improvement of the competitive position of farms and longtermand sustainable rural development. Poland’s accession to the EU hasgenerated new economic and organisational conditions to support structuralchanges in the broadly defined food economy and rural areas. Policy instrumentsimplemented within the CAP create chances for the stabilisation of structuralpolicy conditions over the period of several production cycles, thus stimulating thedesired changes in the area structure of farms, the improvements in thecompetitiveness of production, environmental protection and multi-functionaldevelopment of rural areas. Thus they are a fundamental instrument supporting theprocess of modernisation of Polish rural areas and agriculture. The articleconclusions refer to structural changes and to competitiveness of agri-food sector.
Virtual Screening of Indonesian Herbal Database as Adenosine A2A Antagonist using AutoDock and AutoDock Vina

Parkinson’s disease is a chronic progressive neurodegenerative disorder. The main feature of Parkinson’s disease is the loss of dopaminergic neuron from subtantia nigra pars compacta (SNc) with Lewy body formation. Based on worldwide data analysis, the prevalence of Parkinson’s disease is 5.2 million people and high at the age above 40 years with the prevalence of men 1.8 times greater than woman. In Indonesia, as many as 1 in a million people suffer from Parkinson’s disease.1
Investigating Immersion and Learning in a Low-Embodied versus High-Embodied Digital Educational Game: Lessons Learned from an Implementation in an Authentic School Classroom

Immersion is often argued to be one of the main driving forces behind children’s learning in digital educational games. Researchers have supported that movement-based interaction afforded by emerging embodied digital educational games may heighten even more immersion and learning. However, there is lack of empirical research warranting these claims. This case study has investigated the impact of high-embodied digital educational game, integrated in a primary school classroom, on children’s immersion and content knowledge about nutrition (condition1 = 24 children), in comparison to the impact of a low-embodied version of the game (condition2 = 20 children). Post-interventional surveys investigating immersion indicated that there was difference only on the level of engagement, in terms of perceived usability, while children’s learning gains in terms of content knowledge did not differ among the two conditions. Interviews with a subset of the children (n = 8 per condition) resulted in the identification of (a) media form, (b) media content and (c) context-related factors, which provided plausible explanations about children’s experienced immersion. Implications are discussed for supporting immersion in high-embodied educational digital games.
Histopathological Evaluation of the Efficacy for Plant-produced E2 Protein Vaccine against Classical Swine Fever Virus (CSFV) in Piglets

Sun-Young Kim, Bo-Kyoung Jung, Gyu-Nam Park, Hye-Ran Kim, Dong-Jun An, Eun-Ju Shon and Kyung-Soo Chang 1Department of Pathology, Dongnam Institute of Radiological and Medical Sciences, Busan 46033, Republic of Korea; 2Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan, Busan 46252, Republic of Korea; 3Animal and Plant Quarantine and Inspection Agency (QIA), 177, Hyeoksin 8-ro, Gimcheon-si, Gyengsangbuk-do 39660 Republic of Korea; 4Department of Clinical Laboratory Science, College of Medical Sciences, Daegu Haany University, Gyeongsan 38610, Republic of Korea; 5BioApplications Inc., Pohang Techno Park Complex, 394 Jigok-ro Nam-gu, Pohang 37668, Korea; 6Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang 37673, Korea
On the Approximate Solving of Dual Fuzzy Matrix Equations

In 2014, Gong et al. proposed a simple method for solving dual fuzzy matrix equations in $LR$ form. Later, Kaur and Kumar showed that there is a technical flaw in their method and it is valid only for certain types of $LR$ dual fuzzy matrix equations. The main aim of this paper is to eliminate this technical flaw and also correct some numerical results obtained by Gong et al.
“Folding of an FTZ-derived peptide by molecular dynamics”

1 Περίληψη. 2 Chapter 1: Introduction 1.1 Proteins.3 1.2 The chronicles of the protein folding problem.4 1.3 Models of protein folding.5 1.3. a Hydrophobic collapse hypothesis.5 1.3. b Diffusion – collision hypothesis.6 1.3. c Nucleation – Condensation mechanism.6 1.3. d Folding funnels – Energy landscapes.7 1.4 Protein Folding Experiments Experimental Approaches.9 1.5 FTZpep and FTZ – F1 receptor.10 1.6 Purpose of the present thesis.12 Chapter 2: Molecular Dynamics Simulation 2.
Graduate Management Admission Test Outcomes and the academic achievement: A study on Masters of Business Administration students

This study investigates whether the outcomes of the Graduate Management Admission Test (GMAT) can predict the academic achievement of enrollees in masters programs. The study is based on administrative data of 516 Masters of Business Administration (MBA) enrollees at the College of Business and Management Science, Makerere University in the 2011 and 2012 enrollment cohorts. The Cumulative Grade Point Average (CGPA) in the bachelor’s degree and that of the first year of master’s studies were adopted as measures of the academic achievement of enrollees. In the analysis, academic achievement of MBA enrollees was modeled using a robust regression by GMAT scores obtained during admission to the program and student characteristics—gender, other qualification, year of completion and outcome of the bachelor’s degree, and whether the candidate obtained his/her bachelor’s degree from Makerere University. In the results, a high GMAT score was significantly associated with high academic achievement among graduate students. This evidence suggests that the theory of an aptitude or admission test being a predictor of academic achievement of learners holds across disciplines. However, a significant association established in the results between the academic achievement of learners at the undergraduate and graduate stages indicates that the undergraduate achievement can be recommended as a cost free alternative for assessing the competence of candidates suitable for admission to the graduate program.
Design optimization of piezoelectric energy harvesting cantilever for medical devices

Energy harvesting from the human body is considered as an effective solution for powering biomedical systems. In particular, the piezoelectric energy recovery from mechanical vibrations of the human body represents the most promising solution. The harvested power depends on several factors such as the geometry, the size and materials used for the piezoelectric cantilever. In addition, the reduction and the change of the design of the piezoelectric system constitute a process for increasing the output power. In the present paper, the conventional rectangular shape of the piezoelectric energy harvester is studied and different shapes of cantilever are investigated. We introduced thus a triangular and a new shaped cantilever which permits the enhancement of the scavenged power for low frequencies. In addition, simulations result of various structures are compared and performed by employing finite element method (FEM). Simulations results show that the proposed form generates an electric power of 145 µW at resonant frequency of 8.5 Hz. This novel shape provides more efficient performance compared to other designs.
Android-App-Dissection on the Wandboard – Automatic Analysis of Malicious Mobile Code

Android-based devices are the main target for cyber criminals. Especially, there is a broad range of malware for the Android platform. The analysis of the malicious code is an important challenge for the law enforcing agencies and developers of antivirus suites. To make the matters worse anti-forensic technologies are widespread in Android malware. To overcome this issue a new platform for the automatic analysis of mobile malicious code is presented. In contrast to existing frameworks the platform is based on the Wandboard hardware platform and supports various Android versions, the functionality is configurable. It is impossible for anti-forensic functions to detect the analysis environment because of the underlying hardware. The platform does both static and behavioural analysis of the malware. The results are presented in a report. The complete platform is easy to use and distributed as a web service. The result of an exemplary malware dissection is presented.
Biomechanical Analysis of Restored Teeth with Cast Intra-Radicular Retainer with and Without Ferrule

The intra-radicular post is used to provide retention to a core, but would also have the function of distributing the functional load in a larger area of the remaining coronary structure and dental root. However, many authors (Assif & Gofil, 1994; Martinez-Insua et al., 1999; Rundquist & Versluis, 2006; Whitworth et al., 2002) have been demonstrating that this reconstruction method doesn't restore the original strength of a vital tooth, what is attributed to the wedge effect that this restoration type causes and to the stiffness difference between the post and the tooth.
SPONTANEOUS PNEUMOTHORAX SECONDARY BRONCHIAL CARCINOMA. Bronşiyal karsinomaya bağlı spontan pnömotoraks.

ABSTRACT Secondary spontaneous pneumothorax occurs in people with a wide variety of pulmonary pathology especially in chronic obstructive pulmonary disease, bullous emphysema, bronchial asthma, congenital cysts, malignancies, interstitial fibrosis, pneumonia and cystic fibrosis. Secondary spontaneous pneumothorax is a life-threatening condition due to underlying chronic pulmonary pathology and commonly seen in elderly patients. In this case we want to remind possibility of underlying pulmonary malignancy with pneumothorax in an elderly patient. OZET Sekonder spontan pnomotoraks bulloz anfizem, konjenital kist, tumorler, interstisiyel fibrozis, pnomoni ve sistik fibrozis gibi kronik obstruktif hastaliklari takiben daha fazla gorulmektedir. Sekonder spontan pnomotoraks hayati tehdit eden bir patoloji olup yaslilarda daha sik gorulmektedir. Bu vaka nedeniyle malignitelere bagli olarak gelisen bir olguyu irdeledik.
Use of systems change and health information technology to integrate comprehensive tobacco cessation services in a statewide system for delivery of healthcare

Despite the availability of effective treatments and recommendations for systems change, full application of the USPublic Health Service clinical practice guideline for the treatment of tobacco use is seldom achieved. The present report describes a comprehensive, structured approach used to implement the guideline and to integrate evidence-based cessation services into a system for delivery of health care. The PRECEDE-PROCEDE model and systems strategies were employed to design and implement the Tobacco Control Initiative (TCI), which provides evidence-based cessation services for the patients of a statewide public hospital system. For the TCI, multi-level assessments, pilot programs, electronic data collection, and performance feedback were needed to produce system-wide changes in workflow and in the quality of care for tobacco users. Although there are advances in health information technology (HIT), systems approaches are required for responding effectively to the Health Information Technology for Economic and Clinical Health (HI-TECH) Act and to standards governing use of electronic data related to treatment of tobacco use and dependence.
Characterization and Development of Average Silhouette Width Clustering

The purpose of this paper is to introduced a new clustering methodology. This paper is divided into three parts. In the first part we have developed the axiomatic theory for the average silhouette width (ASW) index. There are different ways to investigate the quality and characteristics of clustering methods such as validation indices using simulations and real data experiments, model-based theory, and non-model-based theory known as the axiomatic theory. In this work we have not only taken the empirical approach of validation of clustering results through simulations, but also focus on the development of the axiomatic theory. In the second part we have presented a novel clustering methodology based on the optimization of the ASW index. We have considered the problem of estimation of number of clusters and finding clustering against this number simultaneously. Two algorithms are proposed. The proposed algorithms are evaluated against several partitioning and hierarchical clustering methods. An intensive empirical comparison of the different distance metrics on the various clustering methods is conducted. In the third part we have considered two application domains\textemdash novel single cell RNA sequencing datasets and rainfall data to cluster weather stations.