Miracle-dz/UniFAR-FTUs huggingface dataset:
Current lifestyle and exclusive breastfeeding: an impossible balance?

Abstract 427 women were included in this observational cohort study to determine the rate of exclusive (EB), mixed (MB) and artificial breastfeeding (AB) and the personal reasons and social factors influencing this decision. An initial survey was conducted within the first 36 h postpartum and a second wave was carried out 3 months after delivery. 55.74% (238) of the patients intended to EB, 32.55% (139) AB and 11.71% (50) MB. After 3 months, a high percentage in group EB (75.23%) maintained EB. The main reason for switching to AB was the absence of milk or weight loss of the newborn. In conclusion, EB is the preferred form for feeding newborns. When these women returned to their workplace, most of them wanted to continue with EB. Women with higher academic degrees chose more often EB. IMPACT STATEMENT What is already known on this subject? The benefits of exclusive breastfeeding are well known. However, in modern western societies, it is not easy to combine breastfeeding with day-to-day activity. Work activity, age or previous parity are some of the factors that may influence the election of the type of lactation. What do the results of this study add? Exclusive breastfeeding is the preferred method for feeding newborns immediately postpartum and 3 months later. Work activity does not seem to influence or to switch the choice. However, the level of education could be a determinant of adherence to exclusive breastfeeding. What are the implications of these findings for clinical practice and/or further research? Assessing the factors that favour adherence to exclusive breastfeeding might be a useful tool to its promotion. This study warrants further multivariate analyses on the same topic and additional studies in other social contexts.
Training diabetes healthcare practitioners in motivational interviewing: a systematic review

ABSTRACT Diabetes presents significant self-care challenges that require sustained motivation. Motivational Interviewing (MI) has substantial support in enhancing motivation for behavioural change, but its effective application in routine healthcare requires practitioners to acquire and use related skills. The aim of this systematic review was to investigate the impact of MI training on MI-related skills of practitioners who provide diabetes healthcare. PubMed, EMBASE and PsycINFO were searched using the terms motivational interviewing, motivation enhancement, and diabetes. Two assessors independently screened titles, abstracts and full texts for papers reporting the impact of MI training on diabetes healthcare practitioners’ outcomes. Of 625 abstracts screened, 22 papers from 17 unique studies were included. All 17 studies reported some improvement in MI skills, with 14 finding improvements in more than 50% and three less than 35%. However, the risk of bias and outcome measures varied widely between studies. All studies showed diabetes healthcare practitioners acquired and applied MI skills post-training, to varying levels. Findings suggest training should include education, role play, and ongoing supervision to maintain skills.
Dysregulation of Rnf 213 gene contributes to T cell response via antigen uptake, processing, and presentation

Growing evidence suggest the association between Moyamoya disease (MMD) and immune systems, such as antigen presenting cells in particular. Rnf213 gene, a susceptibility gene for MMD, is highly expressed in immune tissues, however, its function remains unclear. In addition, the physiological role of RNF213 gene polymorphism c.14576G > A (rs112735431), susceptibility variant for MMD, is also poorly understood. By studying Rnf213‐knockout (Rnf213‐KO) mice with deletion of largest exon32 and Rnf213‐knockin (Rnf213‐KI) mice with insertion of single‐nucleotide polymorphism corresponding to c.14576G > A mutation in MMD patients, we aimed to investigate the role of RNF213 in dendritic cell development, and antigen processing and presentation. First, we found a high level of Rnf213 gene expression in conventional DCs and monocytes. Second, flow cytometric and confocal microscopic analysis revealed ovalbumin protein‐pulsed Rnf213‐KO and Rnf213‐KI DCs showed impaired antigen uptake, proteolysis and reduced numbers of endosomes and lysosomes, and thereby failed to activate and proliferate antigen‐specific T cells efficiently. In addition, Rnf213‐KI DCs showed a similar phenotype to that of Rnf213‐KO BMDCs. In conclusion, our findings suggest the critical role of RNF213 in antigen uptake, processing and presentation.
Small molecule anticancer drugs.

: Currently there is an intensive drug discovery effort aimed at introducing more selective cancer drugs into the clinic which exploit various targets emerging from the increasing molecular understanding of the disease. Examples include inhibitors of the RAS processing enzyme, farnesyl transferase, the first of which, R115777 (Janssen Pharmaceutica BV) and L778123 (Merck & Co) have entered phase I. In both cases, myelosuppression was dose-limiting; evidence of antitumor activity has been observed with R115777. There is a lot of interest in targeting cyclin-dependent kinases (cdk): flavopiridol (Hoechst AG), a broad-spectrum inhibitor of cdk1, cdk2 and cdk4 is now entering phase II trials. However, in the above two cases, it is now not clear that the in vivo effects of these molecules are due to specific effects against their originally proposed targets. More selective cdk inhibitors are under development. Other targets being studied at the preclinical level, which may result in new therapies in the next five years, are inhibitors of telomerase, MDM2 and c-Raf.
Effect of Pragya Yoga and Pranakarshana Pranayama ( Popounded by Acharya Sriram Sharma ) on Self-Concept level of Juvenile delinquents .

Background: Juvenile delinquency is the result of negative self concept. Self concept is essence of personality. Aim: To Study the effect of PragyaYoga and Parnakarshana Pranayama (PYPP) on self-concept level of juvenile delinquents. Methodology: This prospective study was done on juvenile delinquents of Chhattisgarh, India in 2009 and awarded PHD from DSVV Haridwar. For this study permission was obtained from superintendent of Juvenile care home, Mana Durg, and Raipur (C.G) India. A total hundred (N=100) participants were selected by Experimental control group design. 14 to 18 years juvenile delinquents were selected for this study. All participants were divided in two groups. An experimental group (N=50) and a control group (N=50). The groups were divided in such a way that there was no statically significance difference in baseline mean between both the groups. The practice of Pragya Yoga and Pranakarshana Pranayama (PYPP) was done regularly for 45 days by the experimental group. In this study to measure self-concept level the self-concept scale constructed by Dr. R.K Saraswat has been used. Received data was analysed by T-test. According to statistical analysis, obtained result is significant at 0.01 level, which makes it clear that practice of Pragyayoga and Pranakarshana Pranayama (PYPP) leads to significant improvement of self-concept of juvenile delinquents. © 2020 IJOYAS. All rights reserved. International Journal of Yoga and Allied Sciences journal homepage: www. indianyoga.org//
Chapter 6 Pathophysiology of Coronary Microvascular Dysfunction

Coronary microvascular dysfunction (CMD) has been implicated in a wide spectrum of cardiovascular disease. The underlying mechanisms of CMD appear to be heterogeneous, including several structural and functional alterations. Among them, central to coronary vasomotion abnormalities are threefold: enhanced coronary vasoconstrictive reactivity (i.e. coronary spasm) at epicardial and microvascular levels, reduced endothelium-dependent and -independent coronary vasodilator capacity, and increased coronary microvascular resistance, all of which can cause myocardial ischemia due to CMD and often coexist in various combinations even in the absence of obstructive coronary artery disease. The endothelium plays essential roles in modulating vascular tone by synthesizing and releasing endotheliumderived relaxing factors, including vasodilator prostaglandins, nitric oxide (NO), and endothelium-dependent hyperpolarization (EDH) factors in a distinct vessel size– dependent manner; NO mainly mediates vasodilatation of relatively large, conduit vessels (e.g. epicardial coronary arteries), while EDH factors in small resistance vessels (e.g. coronary microvessels). Endothelium-derived hydrogen peroxide (H2O2) is a physiological signaling molecule serving as one of the major EDH factors especially in coronary microcirculation and has gained increasing attention in view of its emerging relevance for cardiovascular disease. In this chapter, we will briefly summarize the latest knowledge on the pathophysiology of CMD with a special reference to endothelial modulation of vascular tone mediated by H2O2/EDH factor and coronary microvascular spasm, in addition to discussing clinical implications of and therapeutic approaches to CMD in cardiovascular disease.
Strategy and innovation of home based enterprises for local development in the 4.0 era: a bibliographic study

A promotion in entrepreneurship at the household level through efforts in using space at home can lead to Local economic development. By using the house as a place of business, it only needs a limited budget. This type of business contributes to increasing income for households, even in times of crisis. Many studies of Home-Based Enterprises (HBEs) proves that this can contribute to improving household welfare, even on a broader scale that is contributing to local and regional development. HBEs are very adaptive and start using technology. The ability to adapt is inseparable from the strategy and innovation carried out both in terms of ‘software’, namely human resources, or ‘hardware’ readiness, namely technology and or tools that support development including in the Industrial Revolution 4.0 era. The purpose of this paper is to identify the framework of strategy and innovation of HBEs’ development in the Industrial Revolution 4.0 era based on book or articles published in international journals. The importance of the study is in mapping patterns of strategies, and successful innovations produce a strategy model and entrepreneurial innovation. It aims to deconstruct concepts, strategies and innovations related to the development of HBE that contribute to local development in the 4.0 era based on creativity and innovation, and related technology and tools used for development. The results is HBEs can develop through innovations in technology adoption consists of the using of Webite, Social Media, E-Commerce, Mobile Application, and ICT, and the strategies need multi stakeholders namely University and Large Firms to transfer knowledge and technologies; Government to provide supporting laws and regulation, policies and programmes; and the actor of HBEs in increase capacity to adopt new technologies. HBEs will benefit from doing the right strategy and innovation. From these benefits, HBEs will simultaneously improve its local economy, as well as successfully face the challenges of the industrial revolution 4.0.
High-Energy All-Solid-State Symmetric Supercapacitor Based on Ni3S2 Mesoporous Nanosheet-Decorated Three-Dimensional Reduced Graphene Oxide

The hybrid approach offers opportunities to simultaneously exploit the features of capacitive (especially carbon) and faradaic (redox electroactive) materials to increase energy density and power density of supercapacitors. To achieve an optimized overall electrochemical performance, we have synthesized a hybrid supercapacitor electrode consisting of vertically aligned Ni3S2 mesoporous nanosheets on three-dimensional reduced graphene oxide (Ni3S2/3DrGO) supported by Ni foam with a controllable composition and morphological structure, which thus improve the electrical conductivity as well as provide more chemical reaction sites and shorten the migration path for electrons and ions. By taking advantage of the rational structural features and excellent electrical conductance ability, the Ni3S2/3DrGO hybrid nanostructure shows greatly improved electrochemical capacitive performance, including high specific capacitance of 1886 F g–1 (1621 F g–1) at current density of 1.0 A g–1 (20.0 A g–1) and excellent rate c.
Technology Acceptance Model and Motivation-Opportunity-Ability Theory Influences on Indonesian Dota2 Gamer Customer to Customer Online Know-How Exchange

This study conceptualizes the influences of technology acceptance model (TAM) and motivation-opportunity-ability (MOA) theory on customer to customer online gamer knowhow. Although both TAM and MOA are well acknowledged and popularly applied in the literature, implementing both theories using the Indonesian online gamers scenario like Dota2 has not been carried out. This study reviews on the suitability of the theories to be extended into the virtual realm of Dota2. To achieve an understanding on this possibility is significant as the world is changing due to globalization and advancement of technology. This review has established the foundations of MOA theory in Multiplayer Online Battle Arena (MOBA) game environments. This indicates the possibility for the influences of perceived usefulness and perceived ease of use, motivation, opportunity and ability to be investigated on customer to customer online know how. The theoretical framework developed that explains the causal relationship among variables is based on the situational prime of Dota2. It is expected that future video game development based on this study’s framework can aid in the improvement of its players know-how.
Biodegradable foam tray based on sago starch with beeswax as coating agent

Biodegradable foam is an original packaging as a styrofoam alternative. Sago starch is used to produce biodegradable foam because of its huge amount, low-cost, and high biodegradability. Starch as a prospectus foam material is sensitive to water due to its hydrophilic properties. Thus, improvement is necessary to boost its water resistance capability. Coating the foam with a hydrophobic material prevents water contact with the starch. In this work, Beeswax was used as a coating agent due to its hydrophobicity. The purpose of this work to determine the concentration and time of beeswax coating on the mechanical properties of biodegradable foam. Beeswax was varied at 0, 2, 4, 6, 8, and 10% wt concentration with coating duration process for 30, 60, 90, 120, and 150 seconds. Biodegradable foam was produced by baking process at 80°C for 1 hour 20 minutes. The results showed that the beeswax coating process increases the water resistance, although it does not significantly affect the tensile strength. Beeswax addition as much as 4% wt. for 150 seconds had improved the biodegradable foam properties as much as 1.92%, 73% in 28 days, and 0.09 MPa for water absorption capability, biodegradability, and tensile strength, respectively.
Heart Rate Variability (HRV) during anger emotion stimulation: features for affective

Recent studies have revealed the relationship between human Emotion and health. Researchers are trying to find the best features to distinguish human Emotion through its psychophysiology signals in the Affective Computing study. Humans have six basic emotions, such as Anger, Sadness, Happy, Surprise, Fear, and Disgust. Emotions affect human ANS (Autonomous Nervous System). The heart is one of the human inner organs affected by the ANS (working under ANS). Heart rate is one of the Psychophysiological signals that changed depends on human Emotion. This study tried to analyze the difference between human heart rate during Anger and Normal Emotion Stimulation. Video Stimuli were used to Evoke Emotion. 15 Participant’s heartbeats were recorded using an ECG sensor from E-Health Sensor Platform v2.0. We used HRV (Heart Rate Variability) MeanRR feature as a comparison. Some studies said that experiencing long-term Anger Emotions can cause serious illness to the human body. There are some differences in the MeanRR feature between ANGER State and NORMAL State. The findings of this investigation complement those of earlier studies about HRVi. This research supports the idea that HRV can be used as a feature to detect human affect state.
Fire reduces riverine DOC concentration draining a watershed and alters post-fire DOC recovery patterns

The loading of dissolved organic carbon (DOC) from soils to inland waters and ultimate transport to the ocean is a critical flux pathway in the terrestrial biosphere carbon cycle. Fires can significantly affect this flux through biogeochemical processes related to oxidation and mobilization of DOC in the soil. Therefore, in order to accurately estimate and model terrestrial carbon storage and export to the marine environment, we need to better understand the effects of fire on DOC flux. In this analysis, we compiled available observational data sets from seven watersheds across the conterminous United States generally spanning the years 1999–2019. We used these data sets to examine the effects of fire on riverine DOC concentration draining a watershed to study both the immediate impacts and the post-fire recovery patterns. Our results suggest that these fires result in an immediate decrease in riverine DOC concentration draining the watershed by 26 ± 15%, and the time required for DOC concentrations to recover to pre-fire levels was estimated to be, on average, approximately 9 months. During recovery, DOC concentration was 24 ± 11% lower than the long-term average for the watershed. In addition, the larger the proportion of the watershed that burned, the greater the concentration decrease and the longer the time period for post-fire recovery.
The Influence of Nano-Silica on the Properties and Microstructure of Lightweight Concrete: a Review

In recent years, the use of nanotechnology materials has increased in strengthening and enhancing the behavior of concrete and its mechanical properties. This is due to the special characteristic of these materials such as its tiny size that considerably improves the microstructure of concrete, which in return gives concrete new properties and dramatically enhances its behavior. The present study seeks to review several previous studies that investigated the effect of adding nano-silica on the mechanical properties, durability, transport properties, and microstructure of lightweight concrete. Based on the results, it has been noted that the addition of nano-silica material has a vital role in improving the properties of lightweight concrete. Moreover, it was observed that there is an increase in the compressive strength, tensile strength, and flexural strength due to the addition of nano-silica material. It has also been concluded that there is an improvement in the durability and transport properties of lightweight concrete.
Descriptive Analysis on Products/Services demand and Market conspectus: A quantitative approach

The research conducted in this paper consists of finding out the shortcomings of Efficient Market Hypothesis as it is purely based on if information is immediately priced in the Trading markets. Efficient market hypothesis(EMH) also suggests that it is not possible for someone to give more returns than the market in long term, Which has been disproven in this research using multiple criteria decision making and taking the companies with Good Debt to Market cap ratio and check their aggregated outcome over a long period of time and the rate of return came out to be significantly higher than the growth in the market. One of the main assumptions of EMH also happens to be that fundamental analysis does not affect stock market or stock indexes but its proven to be false as in long term if indexes are selected based on good criterias. Efficient market hypothesis says that stock prices depend on news and the news of the next day is by default unpredictable, but it doesn't take into account the fact that not everyone interprets the news in the same way and even if they do they don't process the information on the same intensity.
Semiclassical backreaction on asymptotically anti–de Sitter black holes

We consider a quantum scalar field on the classical background of an asymptotically anti--de Sitter black hole and the backreaction the field's stress-energy tensor induces on the black hole geometry. The backreaction is computed by solving the reduced-order semiclassical Einstein field equations sourced by simple analytical approximations for the renormalized expectation value of the scalar field stress-energy tensor. When the field is massless and conformally coupled, we adopt Page's approximation to the renormalized stress-energy tensor, while for massive fields we adopt a modified version of the DeWitt-Schwinger approximation. The latter approximation must be modified so that it possesses the correct renormalization freedom required to ensure the semiclassical equations are consistent. Equipped with these approximations, the reduced-order field equations are easily integrated and the first-order (in $\ensuremath{\hbar}$) corrections to the metric are obtained. We also compute the corrections to the black hole event horizon, surface gravity, and minimum temperature as well as corrections to the photon sphere and quadratic curvature invariants. We pay particular attention to the temperature profiles of the semiclassical black holes compared with their classical counterparts, pointing out some interesting qualitative features produced by the backreaction. These results ought to provide reasonable approximations to the first-order (one-loop) quantum backreaction on the geometry of asymptotically anti--de Sitter black holes when the exact numerical stress-energy tensor sources the semiclassical equations.
Flow and interferometry results from 
Au+Au
 collisions at 
sNN=4.5
 GeV

The beam energy scan (BES) program at the BNL Relativistic Heavy Ion Collider (RHIC) was extended to energies below sNN=7.7 GeV in 2015 by successful implementation of the fixed-target mode of operation in the STAR (Solenoidal Tracker At RHIC) experiment. In this mode, ions circulate in one ring of the collider and interact with a stationary target at the entrance of the STAR time projection chamber. The first results for Au+Au collisions at sNN=4.5 GeV are presented, demonstrating good performance of all the relevant detector subsystems in fixed-target mode. Results presented here include directed and elliptic flow of identified hadrons, and radii from pion femtoscopy. The latter, together with recent HADES results, reveal a long-sought peak structure that may be caused by the system evolving through a first-order phase transition from quark-gluon plasma to the hadronic phase. Directed and elliptic flow for pions are presented for the first time at this beam energy. Pion and proton elliptic flow show behavior which hints at constituent quark scaling, and demonstrate that a definitive conclusion will be achievable using the full statistics of the ongoing second phase of BES (BES-II). In particular, BES-II to date has recorded fixed-target data sets with two orders of magnitude more events at each of nine energies between sNN=3.0 and 7.7 GeV.