Miracle-dz/UniFAR-FTUs huggingface dataset:
Mitochondrial superoxide simutase. Site of synthesis and intramitochondrial localization.

Abstract Mitochondria were isolated from chicken liver and were then separated into fractions containing the outer membrane, the soluble components of the intermembrane space, the inner membrane, and the soluble enzymes of the matrix space. The manganosuperoxide dismutase was found primarily in the matrix space whereas the cuprozinc superoxide dismutase, previously isolated from the cytosol, was found in the intermembrane space. No activity was associated with the membranous fractions. A strain of petite mutants of Saccharomyces cerevisiae which lacks mitochondrial DNA, was examined and found to contain both the mangano- and the cuprozinc types of superoxide dismutase. This result indicates that the manganoenzyme, although localized in the mitochondrial matrix, is actually made under the directions of the nuclear genome and that its biosynthesis therefore probably takes place in the cytosol.
Visualization of geostress tensor along oil well trajectory

A simple and efficient method is proposed to visualize a symmetric second order tensor along 3D curves. It is also applied to an oil well model in which, along the well trajectory, the spatial distribution of geostress is visualized to predict the stability of the oil well bore. To give visual representations several forms are used: (1) we visually compare the magnitude of stresses to determine the mud weight; (2) based on a set of ellipse cross-sections along the well trajectory and the ellipticity of the ellipse we predict the shear failure direction and the stability of the oil well bore; (3) from a hinged curved surface, we emphasize the direction of principal stresses; (4) to give useful information we apply other skills such as magnified details, animation and an interactive interface. Our method avoids two defects in the references, that is, the visual cluster caused by discrete point tensor glyphs, and the integration problem of the hyperstreamline.
TOXINFECÇÃO ALIMENTAR POR Staphylococcus Aureus ATRAVÉS DO LEITE E SEUS DERIVADOS, BEM COMO O ELEVADO POTENCIAL PATOGÊNICO DE RESISTÊNCIA ÀS DROGAS

Neste trabalho, sao apresentados os principais problemas decorrentes das Toxinfeccoes causadas por Staphylococcus aureus e as consequencias para a saude humana da veiculacao das suas toxinas atraves dos alimentos. O S. aureus destaca-se como um dos microrganismos mais importantes que podem ser transmitidos atraves dos alimentos. Assim discute-se a possibilidade de veiculacao de gastrenterite estafilococica, nao somente atraves do consumo de leite cru contaminado, mas tambem do leite tratado termicamente ou de derivados lacteos contendo enterotoxinas termoestaveis. Sao apresentados alguns aspectos relacionados ao potencial toxigenico das cepas de S. aureus, bem como as principais caracteristicas das enterotoxinas estafilococicas. Palavras-chave: Staphylococcus aureus, enterotoxinas, mastites, saude humana.
Routing anomaly detection in mobile ad hoc networks

Intrusion detection systems (IDSs) for mobile ad hoc networks (MANETs) are necessary when we deploy MANETs in reality. In this paper, focusing on the protection of MANET routing protocols, we present a new intrusion detection agent model and utilize a Markov chain based anomaly detection algorithm to construct the local detection engine. The details of feature selection, data collection, data preprocess, Markov chain construction, classifier construction and parameter tuning are provided. Based on the routing disruption attack aimed at the dynamic source routing protocol (DSR), we study the performance of the algorithm at different mobility levels. Simulation results show that our algorithm can achieve low false positive ratio, high detection ratio, and small MTFA (mean time to the first alarm), especially when the mobility is low. Detailed analysis of simulation results is also presented.
A Monetary Model of the Korean Economy

El objeto principal del presente trabajo es triple: 1) remediar varias caracteristicas de los defectos inherentes a todo sistema de ecuacion unica para explicar un fenomeno monetario; 2) preparar el sistema de ecuaciones simultaneas de un modelo monetario trimestral de la economia coreana y comprobar la validez del modelo con respecto a los datos correspondientes al periodo 1962-74, y 3) analizar, mediante ejercicios de simulacion, las influencias ejercidas por los instrumentos alternativos de politica en las principales variables macroeconomicas, inclusive el producto, los precios y la balanza de pagos. El modelo consiste en un sistema no lineal de cinco ecuaciones de conducta (para inflacion, importacion de bienes intermedios y de bienes de consumo, producto real y sector no primario y razon moneda/deposito) y cinco ecuaciones de identidad. El modelo es monetario en cuanto a que el dinero desempena la funcion central de determinar las variables macroeconomicas esenciales de la economia. Tiene su origen en los modelos monetarios a largo plazo de balanza de pagos establecidos por Polak (1957), Johnson (1972), Dornbusch (1973) y otros. Pero difiere fundamentalmente, en varios respectos, de estos modelos tipicos. En primer lugar, se trata de un modelo a corto plazo en que los precios y el producto real de determinan endogenamente. En segundo, el modelo permite explicar los efectos del impulso monetario en los precios y el producto real. En tercer lugar, el modelo contiene una funcion explicita de la demanda del producto real basada en el comportamiento de la maximizacion de beneficios en la teoria neoclasica y considera, explicitamente, la importancia que los bienes intermedios de importacion causan en la demanda de producto real. Semejante modelo se ha calculado por el metodo bifasico de cuadrados minimos, utilizando datos trimestrales correspondientes al periodo 1962-73. Seguidamente, el modelo calculado se ha sometido a una diversidad de ejercicios de simulacion plenamente dinamicos, para analizar sus propiedades con respecto a estabilidad, capacidad de prevision, etc. Estos ejercicios han indicado lo siguiente: 1) el modelo es estable, tiene buena capacidad de prevision, particularmente dentro del periodo de la muestra, y en general, es valido; 2) reacciona en forma notablemente simetrica ante las conmociones exogenas causadas en las variables fiscal y monetaria, y 3) producira, al menos desde un punto de vista cualitativo, el resultado previsto de variables endogenas como reaccion ante las alteraciones de las variables de politica.
Surgical management of intramedullary spinal cord tumors: functional outcome and sources of morbidity.

We are reporting the functional outcome of 69 of 86 patients affected by intramedullary spinal cord tumors who underwent surgery at our department during the period of 1984 to 1992. The results on 17 patients affected by hemangioblastomas and cavernomas were excluded from this study and will be published separately. Twenty-eight patients had astrocytic processes; 34 had ependymoma; 4 had lipoma; 2 had neurofibroma; and 1 had oligodendroglioma. The overall rate of "radically" resected tumors was 55.1%, as opposed to 17.4% "quasiradically," and 27.5% of "partially" resected processes. There was one postoperative death. Five other patients, affected by anaplastic astrocytomas, died because of tumor progress within 16 months from the operation. A postoperative functional assessment showed that the function of the upper and lower extremities had deteriorated in 65.4 and 55.1% of the patients; a respective functional deterioration by 1 degree of the scale of Cooper and Epstein was registered in 88.8 and 86.8% of the patients. The patients who recovered improved within a period of 6 to 18 months, whereas the function of the dorsal columns was impaired the longest. At follow-up (mean, 54 mo; range, 8-107 mo), the functional recovery (as compared with the preoperative status) was as follows: upper extremity, 17.1% of the patients were improved, 55.5% were unchanged, and 31.5% were worse (89.4% by 1 degree); lower extremity, 22.4% of the patients were improved, 51.5% were unchanged, and 29.4% were worse (most by 1 degree). Surgery on tumors of the cervicothoracic and upper thoracic region carried a relatively higher morbidity in this series. (ABSTRACT TRUNCATED AT 250 WORDS)
The effect on laryngoscopy of different cervical spine immobilization techniques

Fifty patients underwent laryngoscopy with two different cervical spine immobilisation techniques. First the cervical spine was immobilised in a rigid collar with tape across the forehead and sandbags on either side of the neck, then with an assistant providing manual in‐line immobilisation. Finally, patients underwent laryngoscopy in the routine intubating position. In 56% of patients the view of the larynx improved by one grade and in 10% the view improved by two grades when manual immobilisation was substituted for the collar, tape and sandbags (p < 0.0001). There was a poor view on laryngoscopy (grade 3 or 4) in 64% of patients when immobilised in a collar, tape and sandbags compared to 22% of patients undergoing in‐line manual immobilisation (p < 0.001). Mouth opening was significantly reduced when patients were wearing cervical collars and this was the main factor contributing to the increased difficulty of laryngoscopy in this particular form of cervical spine immobilisation. It is recommended that manual in‐line immobilisation should be the method of choice for cervical spine stabilisation during tracheal intubation.
Shot noise behaviour of subthreshold MOS transistors

2014 It is shown that assuming weak inversion, low drain current asymptotic value of the gate equivalent noise resistor is given by n2/2 UT/ID, corresponding to shot noise. Measurements confirming this theory as well as flicker noise measurements on n and p channel transistors integrated with either bulk or SOS CMOS silicon gate technology are presented. REVUE DE PHYSIQUE APPLIQUEE TOME 13, DECEMBRE 1978,
Isolation and Characterization of Mutants of Colicin Plasmids E1 and E2 After Mu Bacteriophage Infection

Cells colicinogenic for the colicin plasmids E1 or E2 (Col E1 and Col E2, respectively) were selected for a loss of colicin production after infection with bacteriophage Mu. Extrachromosomal deoxyribonucleic acid that was larger than the original colicin plasmids was found in such cells. A small insertion mutant in Col E1 deoxyribonucleic acid affecting active colicin production without affecting either expression of colicin immunity or Col E1 deoxyribonucleic acid replication was found. Cells carrying this Col E1 plasmid mutant do not exhibit the lethal event associated with colicin E1 induction, suggesting that synthesis of active colicin is required for killing during induction. The altered Col E2 plasmid, containing an insertion at least as large as phage Mu, was maintained unstably in the mutants examined.
The mental health status of older black Americans: a national study.

ABSTRACTThe present study examined mental health status in a large national sample of the black elderly. Previous studies of mental health and illness in this population have been either geographically limited or based upon small national samples that have not permitted reasonable investigation of important demographic differences. In addition to using traditional measures of self-reported mental health functioning, the present study also included measures of well-being in an attempt to explore the multi-dimensional nature of the mental health concept in the black elderly. The findings of the present analyses indicate a great deal of heterogeneity among the black elderly as well as significant relationships between global measures of well-being and measures of psychological distress. The implications of these findings for a multi-dimensional conception of mental health in black Americans are discussed.
Requêtes Skyline avec prise en compte des préférences utilisateurs pour des données volumineuses

Apprehender, parcourir des donnees ou des connaissances reste une tâche difficile en particulier lorsque les utilisateurs sont confrontes a de gros volumes de donnees. De nombreux travaux se sont interesses a extraire des points "skylines" comme outil de restitution. La prise en compte des preferences a retenu l'attention des travaux les plus recents mais les solutions existantes restent tres consommatrices en terme de stockage d'informations additionnelles afin d'obtenir des delais raisonnables de reponse aux requetes. Notre proposition, EC2 Sky (Efficient computation of compromises), se focalise sur deux points : (1) comment repondre efficacement a des requetes de type skyline en presence de preferences utilisateurs malgre de gros volumes de donnees (aussi bien en terme de dimensions que de preferences) ; (2) comment restituer les connaissances les plus pertinentes en soulignant les compromis associes aux preferences specifiees. / Understanding and browsing of data or knowledge is still a difficult task especially when users are confronted with large volumes of data. A considerable amount of research has focused on extracting "skyline" points as a restitution tool. Most of the recent work has taken the preferences into account, but existing solutions are not very efficient in terms of information storage, as they store additional information to improve response time to queries. Our proposal, EC2Sky, focuses on two points (1) how to respond effectively to requests like skyline, in the presence of user preferences despite large volumes of data (both in terms of dimensions and preferences) (2) how to restore the most relevant knowledge by underlining the associated trade-offs with the specified preferences.
Estatuto terminológico de nombres abstractos meronímicos de referencia general: descripción y propuesta de representación en diccionarios para la producción académica

Los nombres abstractos de denotacion general como problema , fenomeno , factor , de alta frecuencia en textos del ambito academico, han sido estudiados como nombres de segundo y tercer orden (en semantica lexica), shell nouns , nombres anaforicos (en explicaciones de su funcionamiento textual), palabra cientifica general, vocabulario de soporte, paratermino, semitermino (para describir el empleo transversal en diferentes ambitos del saber). Este trabajo estudia nombres abstractos de referencia general que designan relaciones meronimicas, tales como componente, aspecto y factor , con los propositos de contribuir a la descripcion semantica del estatuto terminologico de los nombres abstractos y su comportamiento en textos de especialidad, por un lado, y de colaborar con el diseno de aplicaciones lexicograficas de impacto en la ensenanza de la escritura academica, por otro. Se conjugan dos perspectivas analiticas: la semantica lexica y la linguistica del texto. En una primera parte se ofrece un recorrido bibliografico del tratamiento de los nombres abstractos en estudios de distintas tradiciones. Luego, se expone el analisis ejemplar del nombre factor respecto de la descripcion de la informacion semantica codificada como de su funcionamiento textual. Finalmente se propone una representacion lexicografica para un diccionario de produccion academica.
Photochemistry and Photobiology of Cryptochrome Blue-light Photopigments: The Search for a Photocycle

Abstract Cryptochromes are flavoproteins that exhibit high sequence and structural similarity to the light-dependent DNA-repair enzyme, photolyase. Cryptochromes have lost the ability to repair DNA; instead, they use the energy from near-UV/blue light to regulate a variety of growth and adaptive processes in organisms ranging from bacteria to humans. The photocycle of cryptochrome is not yet known, although it is hypothesized that it may share some similarity to that of photolyase, which utilizes light-driven electron transfer from the catalytic flavin chromophore. In this review, we present genetic evidence for the photoreceptive role of cryptochromes and discuss recent biochemical studies that have furthered our understanding of the cryptochrome photocycle. In particular, the role of the unique C-terminal domain in cryptochrome phototransduction is discussed.
The processing of illegal consonant clusters: A case of perceptual assimilation?

This paper presents evidence from a variety of experimental tasks for a perceptual shift, or assimilation. Consonant clusters that are phonotactically illegal, albeit pronounceable in French, are perceived as legal clusters, close in place and manner of articulation. Specifically, word-initial /dl/ and /tl/ are identified as /gl/ and /kl/, respectively in phonetic decision experiments. Two phonemic gating experiments show that subjects generally judge short gates Ñwhich do not yet contain information concerning the second consonant /l/ Ñ as being dental plosives. However, as information concerning the /l/ becomes available in larger gates, a perceptual shift develops, in which the initial consonants are increasingly judged as being velar plosives. We propose to call this special kind of perceptual shift "contextual perceptual assimilation". A final phoneme monitoring experiment suggests that this assimilation takes place on-line during speech processing, but not without some extra temporal processing cost. These results provide evidence for the automatic integration of low-level phonetic information into a more abstract code determined by the native phonological system.
Comments on “High Performance Inversion-Type Enhancement-Mode InGaAs MOSFET With Maximum Drain Current Exceeding 1 A/mm”

We have a number of issues with the above paper ldquoHigh Performance Inversion-Type Enhancement-Mode InGaAs MOSFET With Maximum Current Exceeding 1 A/mm,rdquo by Y. Xuan, Y. Q. Wu, and P. D. Ye, published IEEE Electron Device Letters in April 2008 which we wish to highlight.
Sustainability, TQM and Value Co-Creation Processes: The Role of Critical Success Factors

Sustainability views firm success and the welfare-wellbeing of societies in which they develop as closely inter-related. Value co-creation assumes that firms create value not only for themselves, but also for all actors willing to participate in co-creation processes, as well as for the whole ecosystem in which they operate. Thus, co-creation can sustain social development and sustainability. However, to ensure sustainability through value co-creation processes, TQM principles must be followed and Critical Success Factors (CSFs) reinterpreted following this perspective. In this important, but understudied context, the aim of the paper is to focus on value co-creation processes fostering sustainability, identifying which CSFs are most suitable to best support each phase of these processes. The paper is based on a review of the literature and bridges sustainability, value co-creation, TQM, EM and IMS literature for the first time, proposing a new model of value co-creation processes, which considers it a never ending cycle. The proposed model presents and discusses, for the first time, the most important CSFs to foster sustainability and opens the discussion on how to re-interpret quality principles, which must also be followed in value co-creation processes.
Adaptaciones de workflows para administración de seguridad mediante MDD y aspectos

Este documento presenta una propuesta para abordar el problema de adaptacion de workflows, mediante la incorporacion de propiedades de seguridad a nivel de modelado de proceso de negocio, controlando el impacto de dicha incorporacion sobre el proceso que se interviene y la gestion de intereses transversales (concerns) que se entrelazan unos con otros. La pro-puesta define como administrar en forma mantenible, reutilizable y extensible los intereses o concerns derivados de las propiedades de seguridad, a nivel de modelos, de acuerdo con el contexto, las variaciones de las normas y requisitos de proceso de negocio, y estandares de seguridad propuestos para entornos de servicios distribuidos.
Female and male entrepreneurs in Sweden and the Netherlands : a test of liberal and social feminism

The purpose of this paper is to propose a nonparametric interest rate term structure model and investigate its implications on term structure dynamics and prices of interest rate derivative securities. The nonparametric spot interest rate process is estimated from the observed short-term interest rates following a robust estimation procedure and the market price of interest rate risk is estimated as implied from the historical term structure data. That is, instead of imposing a priori restrictions on the model, data are allowed to speak for themselves, and at the same time the model retains a parsimonious structure and the computational tractability. The model is implemented using historical Canadian interest rate term structure data. The parametric models with closed form solutions for bond and bond option prices, namely the Vasicek (1977) and CIR (1985) models, are also estimated for comparison purpose. The empirical results not only provide strong evidence that the traditional spot interest rate models and market prices of interest rate risk are severely misspecified but also suggest that different model specifications have significant impact on term structure dynamics and prices of interest rate derivative securities.
Empathie, burn out et caractéristiques sociodémographiques des médecins généralistes

Le burn out est une pathologie de la relation d'aide qui concerne une part importante des medecins francais. Elle entraine une alteration du professionnalisme et de la relation medecin-patient. L’empathie, elle, apparait comme une qualite professionnelle favorable au developpement de la relation therapeutique. Le lien entre ces deux entites est encore mal connu, jamais demontre chez les medecins generalistes francais. L’objectif principal de cette these est de verifier l’existence d’un lien entre empathie et burn out chez les medecins generalistes. Nous avons egalement etudie les caracteristiques sociodemographiques qui influencent l’empathie et le burn out et la correlation des autoevaluations « empathie et burn out » avec l’empathie « reelle », ou precision empathique. La premiere partie de cette etude transversale a porte sur l’analyse de l’empathie, du burn out et de facteurs sociodemographiques chez 308 medecins generalistes francais, par auto-questionnaire. On a ainsi demontre un lien fortement significatif entre les trois dimensions du burn out et l’empathie. Dans la seconde partie, la precision empathique, l’empathie, le burn out et la difficulte de la relation medecin-patient ont ete analyses dans vingt dyades medecins-patients diabetiques, montrant un lien significatif entre precision empathique et empathie emotionnelle. La difficulte de la relation medecin-patient est liee a un burn out plus important, a une plus grande empathie cognitive et a une empathie emotionnelle plus faible. Le burn out est associe a une moindre empathie chez les medecins generalistes francais, avec une question en suspens : l’empathie mene-t-elle au burn out ou en protege-t-elle ?