Miracle-dz/UniFAR-FTUs huggingface dataset:
Using Glucose-bound Fe3O4 Magnetic Nanoparticles as PhotothermalAgents for Targeted Hyperthermia of Cancer Cells

Cancer remains as a top leading cause of death for decades. Thus, efforts have been devoted in exploring effective therapeutic methods of treating patients suffering from the disease. In this study, we proposed a targeted hyperthermia approach that can be used to inhibit the growth of cancer cells by combining functional iron oxide (Fe3O4) magnetic nanoparticles (MNPs) with illumination of near-infrared (NIR) light. Cancer cells express more glucose receptors on their cell membrane than normal cells. Furthermore, Fe3O4 MNPs are known to possess photothermal features. An aqueous solution containing the generated MNPs (1 μg μL-1, 100 μL) can be heated from 37°C to over 50°C under irradiation of a NIR laser (808 nm) within 3 min. We immobilized glucose-6-phosphate on the surface of Fe3O4 MNPs (Glu-Fe3O4 MNPs) through phosphate-Fe(III) chelation and used the generated glucose functionalized MNPs as probes to target cancer cells, i.e., hepatocellular, breast, and prostate cancer cells, in which different amounts of Glu receptors were expressed in their cell membrane. After irradiating the MNP-target cell conjugates using a NIR laser (808 nm), the growth of cancer cells containing more Glu receptors can be better inhibited than normal cells containing fewer receptors within 1 min. More than 90% of these cancer cells were killed under NIR light irradiation within 3 min. The results showed that the Glu-Fe3O4 MNP-targeted hyperthermia approach can effectively inhibit the growth of cancer cells. On the basis of the targeting capacity of the Glu-Fe3O4 MNPs against cancer cells, the Glu-Fe3O4 MNP probes can be potentially used as universal probes for the photothermal hyperthermia of cancer cells.
Nanog overexpression allows human mesenchymal stem cells to differentiate into neural cells——Nanog transdifferentiates mesenchymal stem cells

Although stem cell therapies have been proposed as a candidate for treating neurological diseases, the best stem cell source and their therapeutic efficacy remain uncertain. Embryonic stem cells (ESCs) can efficiently generate multiple cell types, but pose ethical and clinical challenges, while the more accessible adult stem cells have a limited develop-mental potential. Following included-expression of Nanog, an ESC gene, adult human mesenchymal stem cells (HMSCs) are able to develop into cells exhibiting neural cell-like characteristics based on morphology, cell markers, and gene expressions. After expansion, Nanog overexpressed HMSCs differentiated into cells immunopositive for betaIII-tubulin and glial fibrillary acidic protein, lineage markers for neurons and astrocytes, respectively, under the influence of con-ditional media from differentiated human neural stem cells. This result indicates that the Nanog expression increased the ability of HMSCs to become a neural cell lineage. We further demonstrated that Nanog-overexpressed HMSCs were able to survive, migrate, and undergo neural cell-like differentiation after transplantation in vivo. This data offers an exciting prospect that peripheral adult stem cells can be modified and used to treat neurological diseases.
Conductive Characteristics of Indium Tin Oxide Thin Film on Polymeric Substrate under Long-Term Static Deformation

The objective of this study is to investigate the effect of long-term static bending on the conductive characteristics of indium tin oxide (ITO) thin film in flexible optoelectronics. Two types of substrate are considered, namely ITO on polyethylene naphthalate (ITO/PEN) and ITO on polyethylene terephthalate (ITO/PET). Electrical properties of the ITO/PEN and ITO/PET sheets are measured in situ under static bending at various radii of curvature. Experimental results indicate that no significant change in electrical resistance of the ITO/PEN and ITO/PET sheets is found for compressive bending after 1000 h at a curvature radius of 10 mm or larger. However, the ITO/PEN and ITO/PET sheets are seriously damaged under a tensile bending of 10 mm radius and 5 mm radius, respectively. The given ITO/PET sheet exhibits a greater resistance to long-term mechanical bending than the ITO/PEN one, which is attributed to the effect of stiffness and thickness of substrate. As the given PET substrate has a lower stiffness and thickness than the PEN one, ITO thin film in the ITO/PET sheet has a smaller stress given a bending radius. Consequently, a smaller extent of change in the electrical conductance of ITO thin film is found in the ITO/PET sheet.
Automatic Metadata Extraction from Spoken Content using Speech and Speaker Recognition Techniques

Abstract Today information extraction plays a signiﬁcant role in manage-ment of massive data quantities for different purposes. One ofthe open challenges in this ﬁeld is the automatic extraction ofinformation from audio streams. This paper describes a usefulmetadata extraction system which performs a powerful com-bination of speech and speaker recognition tasks. The systemcarries out the speech transcription through a Catalan languagerecognizer based on Hidden Markov (HMM) tied-state cross-word triphones acoustic models, Mel Frequency Cepstral Cod-ing (MFCC) and N-gram language modeling. In addition, aspeaker diarization is performed using HMM based segmen-tation and Perceptual Linear Prediction (PLP) feature extrac-tion. Both speech-to-text transcription and speaker diarizationcan be utilized as annotation data for multimedia content. Inorder to make indexing and retrieval more ﬂexible and efﬁcient,the extracted metadata is stored using the MPEG-7 multimediacontent description interface. The system has been successfullytested on the recordings of the plenary sessions of the CatalanParliament.Index Terms: Metadata extraction, Automatic speech recogni-tion, Speaker diarization, GMM, HMM, MPEG-7
Sources of uncertainties in modelling black carbon at the global scale

Abstract. Our understanding of the global black carbon (BC) cycle is essentially qualitative due to uncertainties in our knowledge of its properties. This work investigates two source of uncertainties in modelling black carbon: those due to the use of different schemes for BC ageing and its removal rate in the global Transport-Chemistry model TM5 and those due to the uncertainties in the definition and quantification of the observations, which propagate through to both the emission inventories, and the measurements used for the model evaluation. The schemes for the atmospheric processing of black carbon that have been tested with the model are (i) a simple approach considering BC as bulk aerosol and a simple treatment of the removal with fixed 70% of in-cloud black carbon concentrations scavenged by clouds and removed when rain is present and (ii) a more complete description of microphysical ageing within an aerosol dynamics model, where removal is coupled to the microphysical properties of the aerosol, which results in a global average of 40% in-cloud black carbon that is scavenged in clouds and subsequently removed by rain, thus resulting in a longer atmospheric lifetime. This difference is reflected in comparisons between both sets of modelled results and the measurements. Close to the sources, both anthropogenic and vegetation fire source regions, the model results do not differ significantly, indicating that the emissions are the prevailing mechanism determining the concentrations and the choice of the aerosol scheme does not influence the levels. In more remote areas such as oceanic and polar regions the differences can be orders of magnitude, due to the differences between the two schemes. The more complete description reproduces the seasonal trend of the black carbon observations in those areas, although not always the magnitude of the signal, while the more simplified approach underestimates black carbon concentrations by orders of magnitude. The sensitivity to wet scavenging has been tested by varying in-cloud and below-cloud removal. BC lifetime increases by 10% when large scale and convective scale precipitation removal efficiency are reduced by 30%, while the variation is very small when below-cloud scavenging is zero. Since the emission inventories are representative of elemental carbon-like substance, the model output should be compared to elemental carbon measurements and if known, the ratio of black carbon to elemental carbon mass should be taken into account when the model is compared with black carbon observations.
Ectoparasite infection of Carassius carassius in water resources of west Azerbaijan, Iran

Various parasite species were found in Carassius carassius including Diplostomum spathaceum, Dactylogyrus sp. ,Gyrodactylus sp. Ichthyophthirius multifiliis and Trichodinia sp. They were found in four rivers in West Azerbaijan Province (North-Western Iran). A total of 207 live Carassius carassius from four rivers including Aras (72); Zariyneh (42); Nazlo (58) and Barandoz (35) were studied. Parasitological surveys were carried out on gills and external organs. The results showed that Diplostomum spathaceum (70.83%); Dactylogyrus sp. (38.88%); Gyrodactylus sp. )22.22%); Ichthyophthirius multifiliis (48.61%); Trichodinia sp. (8.33%); Chilodonella sp. (12.50%) and Argulus sp. (76.19%) were found in fish from Aras Rive so that the result showed, Spathaceum (63.79%); Dactylogyrus sp. (36.20%); Gyrodactylus sp. (25.86%); Ichthyophthirius multifiliis (44.82%); Trichodinia sp. (18.96%); Chilodonella sp. (12.06%) and Argulus sp. (6.89%). Argulus prevalence was greater in Barandoz River while Chilodonella in Zariyneh rud River. In Barandoz River, Diplostomum spathaceum (65.71%); Dactylogyrus sp. (37.14%); Gyrodactylus sp. (22.85%); Ichthyophthirius multifiliis (31.42%); Trichodinia sp. (25.71%); Chilodonella sp. (8.57%) and Argulus sp. (5.71%) were reported, respectively. Finally, in Zariyneh rud river, the followings have been reported: Diplostomum spathaceum (76.19%); Dactylogyrus sp. (21.42%); Gyrodactylus sp. (14.28%); Ichthyophthirius multifiliis (52.38%); Trichodinia sp. (23.80%); Chilodonella sp. (14.28%) and Argulus sp. (7.14%). It should be noted that prevalence , intensity and host parasite relationship will be discussed in details in this article.
Relação das Mulheres com a Atividade Física: Uma Revisão Bibliográfica

A expansão das academias no Brasil aconteceu na década de 70 devido a crescente adesão dos indivíduos às práticas de atividade física. O intuito das academias nesta época era de promover a saúde por meio da prática de uma atividade física diária. Mesmo assim, os locais públicos ao ar livre também foram crescendo entre aqueles que não se adaptavam às academias ou que viam a atividade física apenas como meio de lazer.O reconhecimento dos benefícios da atividade física entre os indivíduos despontou na década de 80, quando a prática sistematizada e orientada era capaz de modificar o corpo, auxiliar na resposta do sistema imunológico e na prevenção de doenças cardiovasculares. As mulheres neste cenário, adotaram a rotina de atividades física como uma forma de se firmarem na sociedade como seres independentes e responsáveis pela própria imagem corporal. A musculação para as mulheres nesta época foi a modalidade que mais causou polêmica entre as praticantes e a sociedade por dar forma musculosa no corpo feminino. Apesar dos benefícios reconhecidos, alguns entraves foram citados ao longo deste estudo, como o tempo escasso, os serviços domésticos, a criação dos filhos, a distância física da mulher à academia e as questões financeiras.O profissional de educação física neste contexto é responsável por intermediar a relação mulher versus academia, fazendo que ela se sinta à vontade, acolhida e motivada. Desta forma, as relações interpessoais acabam sendo estimuladas e sendo um dos pilares para a permanência da aluna na academia. Ainda há a necessidade de se pesquisar muito sobre a temática para que os resultados possam servir de referência para as tomadas de decisões das políticas públicas da saúde da mulher.
Recomendação de conteúdo baseada em informações semânticas extraídas de bases de conhecimento

SILVA JÚNIOR, S.M. Content recommendation based on semantic information extracted from knowledge bases. 2017. 102 p. Dissertação (Mestrado em Ciências – Ciências de Computação e Matemática Computacional) – Instituto de Ciências Matemáticas e de Computação, Universidade de São Paulo, São Carlos – SP, 2017. In order to support users during the consumption of products, Web systems have incorporated recommendation techniques. The most popular approaches are content-based, which recommends items based on interesting features to the user, and collaborative filtering, which recommends items that were well evaluated by users with similar preferences to the target user, or that have similar features to items which were positively evaluated. While the first approach has limitations such as overspecialization and limited content analysis, the second technique has problems such as the new user and the new item, limitation also known as cold start. In spite of the variety of techniques available, a common problem is the lack of semantic information to represent item’s features. Recent works in the field of recommender systems have been studying the possibility to use knowledge databases from the Web as a source of semantic information. However, it is still necessary to investigate how to use and integrate such semantic information in recommender systems. In this way, this work has the proposal to investigate how semantic information gathered from knowledge databases can help recommender systems by semantically describing items, and how semantic similarity can overcome the challenge confronted in the cold-start scenario. As a result, we obtained a technique that can produce recommendations suited to users’ profiles, including relevant new items available in the database. It can be observed an improvement of up to 10% in the RMSE in the cold start scenario when comparing the proposed system with the system whose rating prediction is based on the correlation of rates.
Analysis of masks for compressed acquisitions in variational-based pansharpening

—The goal of pansharpening is to generate a fused image having both the high spatial resolution of a panchromatic (PAN) and the high spectral resolution of a multispectral (MS) image. For modern low-cost satellite, we envision a strategy for a compressed acquisition with a matrix of custom sensors, which can be seen mathematically as a linear combination of masked sources. We analyze the effectiveness of different masks, both novel and adapted from the literature, on the quality of a fused product, whose reconstruction is based on a flexible inversion scheme based on a variational approach.
EFFECT OF DIFFERENT LEVELS OF DIETARY BETAINE ON GROWTH PERFORMANCE, FOOD EFFICIENCY AND SURVIVAL RATE OF PIKE PERCH (SANDER LUCIOPERCA) FINGERLINGS

A 6-week feeding experiments were carried out to determine the effects of different levels of dietary betaine on growth performance, food efficiency and survival rate of pike perch which has a critical period during transition feeding. Fingerlings of pike perch were fed with live food (treatment A), without betaine added to biomar (treatment B), 1% betaine added to biomar (treatment C) and 2% betaine added to biomar (treatment D) in 1000 l concreted tanks. 200 fingerlings (1.50 g, mean weight) were stocked in each tank and fed up to 7 meals per day. Higher increment in body weight (4.99 ± 0.73 g), specific growth rate (3.90 ± 0.06) and food efficiency (104.42 ± 4.27) were obtained with treatment D (2% betaine added to biomar). This treatment also showed significant (P<0.05) decrease in food conversion ratio (0.93 ± 0.04) in comparison with other treatments. Highest survival rate was observed in treatment B (biomar without betaine) with a 34.5 % rate and greatest cannibalism (1.03 ± 0.01) was found in treatment D, respectively. It was concluded that betaine could increase the palatability and acceptability of food and could be suitable to weaning the pike perch fingerlings to artificial diet.
Processus de régulation sociale et dynamique des conventions autour du télétravail.Une étude de cas

Constatant les résultats extrêmement mitigés et partiellement inexpliqués des effets du télétravail sur les organisations, cet article propose de s’intéresser au télétravail, en questionnant le processus de décision en amont pour étudier la dynamique sociale à l’œuvre depuis l’accord sur la pratique jusqu’à son usage réel. Dans une perspective critique en gestion, cet article réintroduit la dimension politique inhérente au processus de construction des rapports sociaux en proposant d’articuler la théorie de la régulation sociale et la théorie des conventions. Partant des résultats d’une étude de cas, cet article met en exergue l’émergence de différents phénomènes organisationnels et sociaux tels que le double phénomène de déshumanisation et de ré-humanisation ou encore la réappropriation des temps productifs dans une visée performative de conciliation des sphères privées et professionnelles. Ces premiers phénomènes observés amènent.
Is It Really the Best of Both Worlds? Exploring Notions of Privilege Associated with Multiraciality

This study explores the experiences of privilege among multiracial college students guided by two research questions: (1) How do multiracial students define and identify privilege? And (2) In what ways do multiracial students see experiences of privilege influencing their sense of racial identity? Through interviews with 16 college students at a large, public university in the U.S. Midwest, three themes were found: (a) naming privilege without much ownership or connection to race; (b) identifying and accessing various forms of multiracial privilege; and (c) reflecting on the responsibilities that come with privilege. The findings provide advancements in theory regarding multiracial students’ experiences with privilege toward creating new practices that educate students on the complexities associated with understanding privilege in relation to multiracial identity.
Architectural Techniques for Improving the Power Consumption of NoC-Based CMPs: A Case Study of Cache and Network Layer

The disparity between memory and CPU have been ameliorated by the introduction of Network-on-Chip-based Chip-Multiprocessors (NoC-based CMPS). However, power consumption continues to be an aggressive stumbling block halting the progress of technology. Miniaturized transistors invoke many-core integration at the cost of high power consumption caused by the components in NoC-based CMPs; particularly caches and routers. If NoC-based CMPs are to be standardised as the future of technology design, it is imperative that the power demands of its components are optimized. Much research effort has been put into finding techniques that can improve the power efficiency for both cache and router architectures. This work presents a survey of power-saving techniques for efficient NoC designs with a focus on the cache and router components, such as the buffer and crossbar. Nonetheless, the aim of this work is to compile a quick reference guide of power-saving techniques for engineers and researchers.
Paradoxes of Portfolio Performance Calculation for Wealth Management: Avoiding Reporting Pitfalls

Clients of wealth management banks are usually informed about their portfolio through regular reporting. To maintain client trust, it is important that this reporting be both comprehensive and comprehensible. This reporting is grounded on complex mathematics in order to calculate myriads of profit and loss, performance and risk indicators. As the amount of information provided to clients increases so does the chance that certain elements will be confusing to them, at the risk of undermining their confidence in their wealth management bank. This risk is compounded by the general increase in portfolios of complex financial products involving different time horizons. The reporting is typically a decision aid tool for the client to monitor and control and make investment decisions. One example of such risk is that the calculated risk and performance indicators are delivered to the client with no explanation and can, in some cases, lead to incorrect perception due to misunderstanding of these numbers, even if calculations are correct. A typical example could be that the client is informed that the performance of the portfolio is 7% and in reality, the portfolio is losing money. In this paper, we want to address this kind of problem. As such we have identified a set of typical pitfalls that we are faced within the profession. Then, based on a rigorous reference to the scientific literature we have popularized these pitfalls and employed a series of simple and didactic illustrations to provide an appropriate toolbox in order to reduce the risk of financial reporting misunderstanding. In order to maintain client confidence, we highlight the importance of identifying areas of potential misunderstanding prior to providing reports to clients and of offering clear explanations for unusual numbers. We address the following themes: Profit and Loss Analysis, Performance Calculation, Performance Contribution, Realized and Unrealized Profits and Losses, and Bond Yields.
Central lipid detection and the regulation of feeding behavior

The modern abundance of energy-rich foods combined with a shift to more sedentary lifestyles has led to a thermodynamic imbalance in which excessive caloric intake and reduced energy expenditure account for the prevalence of obesity. In particular, exposure to lipid-rich diet is thought to promote metabolic alteration in peripheral tissue associated with obesity-related diseases. The regulation of energy balance depends on the ability of the brain to provide an adaptive response to change in circulating factors of hunger and satiety. The hypothalamus is particularly regarded as key integrative structure but, aside from hypothalamic-mediated homeostatic control, feeding behavior isalso modulated by sensory inputs, such as tastes and odors,as well as by affective or emotional states. The reinforcing and motivational aspects of food are closely tied to the release of the neurotransmitter dopamine by the mesolimbic system, which is stimulated by calorie-dense foods as well as by most other objects of desire. Therefore feeding behavior is regulated by homeostatic as well as non-homeostatic inputs from the hypothalamus and the mesolimbic region. Interestingly, these structures expressesseveralenzymesinvolvedintheprocessingoftriglycerideandfatty acidandthe recent literature provide growing evidence that fatty acid metabolism within discrete brain regions can function as sensor of nutrient availability directly control the hedonic and the homeostatic aspect of feeding.