Miracle-dz/UniFAR-FTUs huggingface dataset:
Bacteremia associated with cardiac catheterization.

BACTEREMIA during cardiac catheterization has been reported to occur in 4 to 18 per cent of patients undergoing the procedure.1 , 2 However, in both published studies, blood for culture was obtained from the intravascular catheter or the vessel from which the catheter had been removed. It is therefore possible that some of the organisms isolated represented contamination of the external part of the catheter or the site of insertion and that bacteremia is much less frequent during catheterization. The present study was undertaken to determine the true frequency of bacteremia during and after cardiac catheterization as well as that of fever.
Dimerization of Neuronal Calcium Sensor Proteins

Neuronal calcium sensor (NCS) proteins are EF-hand containing Ca2+ binding proteins that regulate sensory signal transduction. Many NCS proteins (recoverin, GCAPs, neurocalcin and visinin-like protein 1 (VILIP1)) form functional dimers under physiological conditions. The dimeric NCS proteins have similar amino acid sequences (50% homology) but each bind to and regulate very different physiological targets. Retinal recoverin binds to rhodopsin kinase and promotes Ca2+-dependent desensitization of light-excited rhodopsin during visual phototransduction. The guanylyl cyclase activating proteins (GCAP1–5) each bind and activate retinal guanylyl cyclases (RetGCs) in light-adapted photoreceptors. VILIP1 binds to membrane targets that modulate neuronal secretion. Here, I review atomic-level structures of dimeric forms of recoverin, GCAPs and VILIP1. The distinct dimeric structures in each case suggest that NCS dimerization may play a role in modulating specific target recognition. The dimerization of recoverin and VILIP1 is Ca2+-dependent and enhances their membrane-targeting Ca2+-myristoyl switch function. The dimerization of GCAP1 and GCAP2 facilitate their binding to dimeric RetGCs and may allosterically control the Ca2+-dependent activation of RetGCs.
Endocrine, blood metabolite, and meat quality changes in goats as influenced by short-term, preslaughter stress.

The purpose of this study was to determine the effects of short-term, preslaughter stress on physiological responses and meat quality in goats of different age groups. The goats (n = 28) were classified into young (6 to 12 mo of age) and old (24 to 30 mo of age) groups, feed deprived overnight, and slaughtered at three different times (replicates). On each slaughter day, goats were either subjected to a 2-h transportation stressor (TS) or remained unstressed in holding pens (NS) before slaughter. Blood samples were collected via jugular venipuncture from TS and NS goats at 2, 1, and 0 h before slaughter. Muscle glycogen and pH were measured on samples from longissimus muscle (LM) collected at 15 min and 24 h postmortem, and instrumental measures of meat color were obtained on the LM after a 24-h chilling period at 4 degrees C. The TS goats had higher plasma cortisol (P < 0.01) and glucose (P < 0.05) concentrations than NS goats. The rates of increase in plasma cortisol, glucose, and nonesterified fatty acid concentrations were greater in TS than in NS goats (stressor treatment x blood sampling time, P < 0.01). Muscle glycogen concentrations were greater (P < 0.05) in NS than in TS goats and higher (P < 0.01) in old vs. young goats; however, pH measured at 15 min and 24 h postmortem was not (P > 0.05) influenced by stressor treatment. Water-holding capacity of meat was not (P > 0.05) influenced by stressor treatment. Older goats had lower (P < 0.01) L* values and greater (P < 0.01) a* and chroma values than the younger goats. The a* and chroma values of loin cuts from young goat carcasses were lower in the TS than NS treatment groups, but this effect was absent in the old goat carcasses (stressor treatment x age, P < 0.05). Cooking loss percentages and shear force values for loin chops aged for 7 d were not (P < 0.05) affected by stressor treatment; however, old goats produced tougher (P < 0.01) loin chops than young goats. These results indicate that short-term preslaughter transport can cause noticeable changes in stress responses and muscle metabolism in goats.
System for Oriya handwritten numeral recognition

To take care of variability involved in the writing style of different individuals, a scheme for off-line Oriya isolated handwritten numeral recognition is presented here. Oriya is a popular script in India. The scheme is mainly based on features obtained from water reservoir concept as well as topological and structural features of the numerals. Reservoir based features like number of reservoirs, their size, heights and positions, water flow direction, topological feature like number of loops, centre of gravity positions of loops, the ratio of reservoir/loop height to the numeral height, profile based features, features based on jump discontinuity etc. are some of the features used in the recognition scheme. The proposed scheme is tested on 3550 data collected from different individuals of various background and we obtained an overall recognition accuracy of about 97.74%.
Renal ageing

The function of the kidney, as well as its morphology, changes markedly with age. The glomerular filtration rate falls progressively, independent of overt pathology. Glomerular, vascular and accompanying parenchymal changes occur and other disorders associated with ageing, such as diabetes and hypertension, have a stochastic deleterious effect on both form and function. Declining renal function with age has important implications, not only for individual homeostasis but also for the use of drug therapy and for the receipt and donation of organs for transplantation. Molecular mechanisms and cellular changes underlying some of the functional and structural changes associated with ageing are becoming clearer, as are some of the ways in which genetic background, age and disease can combine to produce functional damage. Copyright © 2007 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Study on Optimization and Orientation of Leisure Sports Professionals Training Program in China Based on qTeaching in 2030q in the United States

The development plan of "Teaching in 2030" in the United States proposed that learners need to master knowledge and skills in an unprecedented way in a flattening world. Aiming at improving the reasonable layout of class hour and credit hour in the training program for leisure sports professionals, this paper uses the literature and statistical methods to meet the rapid development of modern educational technology and world education, and analyzes the current situation of college talent training programs in China. Besides, it dissects and clarifies the development trends and optimization path of leisure sports professionals training program in China to ensure that the training of leisure sports professionals in China meet the needs of developing flat information age in modern times. Keywords—leisure sports; talent training program; orientation
EFFECT OF EARNINGS MANAGEMENT THROUGH ACCOUNTINGS DEVIATION, ACTIVITIES PROFIT RIIL AND ACRUAL TO TAX AGGRESSIVITY

Book tax difference leads an opportunity for earnings management that management calculates the company's earnings for two purposes each year, ie the purpose for financial reporting based on the principles of financial accounting standards and tax reporting based on tax regulations to determine the amount of taxable income or earnings according to fiscal. The Indonesian tax regulations require that the fiscal profit is calculated based on the accrual accounting method, so that the company does not have to double bookkeeping.This study is aimed to examine the effect of earnings management through accounting irregularity, real earnings activities and accrual earnings activites on tax aggressiveness. The samples used in this study are manufacturing companies listed on the Indonesia Stock Exchange (BEI) in the period 2013-2015. Using pusposive sampling, selected companies data amounted to 80, so the total sample in this study of 240. The data examination in this study uses multiple regression analysis with panel data. The results of this study indicate that accounting irregularity has no significant effect on tax aggressiveness. Meanwhile, real earnings management through operating cash flow has a significant negative effect on tax aggressiveness, real earnings management through decreasing discretionary expenses has a significant positive effect on tax aggressiveness, real earnings management through overproduction has a significant positive effect on tax aggressiveness. Furthermore, accrual earnings management has a significant positive effect on tax aggressiveness. Keywords : Earnings Management, Tax Aggresiveness
A robust design for accessible text entry

This paper describes the author's dissertation research on designing, implementing, and evaluating the Edge Write text entry method. The goal of this research is to develop a method that is highly "robust," remaining accessible and accurate across a variety of devices, abilities, circumstances, and constraints. Edge Write is particularly aimed at users with motor impairments and able-bodied users "on the go. " To date, this research has resulted in versions of Edge Write for PDAs, touchpads, displacement joysticks, isometric joysticks, trackballs, 4-keys, and more, all of which use the same Edge Write alphabet and concepts. The stylus version, for instance, has been shown to be significantly more accurate than Graffiti for both able-bodied and motor-impaired users. Similarly, the trackball version has been shown to be better than on-screen keyboards for some people who use trackballs due to motor impairments. This paper discusses these and other achievements, and points towards future work on a mobile phone version for situationally-impaired users. From its inception, Edge Write has been developed with the help of participants, both able-bodied and motor-impaired.
Designing Progress Tracking System for Laboratory to Promote Effectiveness in Providing Information to Customers

The main objective of this research is to improve the current flow of information in the laboratory as it is found to be ineffective to reach the customers. This research is necessary and demanded to be finished as soon as possible as it may affect the product development in Toy Manufacturing company. To solve the information flow problem, it is then initiated the idea to develop a new progress tracking system, which is supposed to be able to provide real-time information to customers and make them able to react faster to problems. Lack of information in the problem could lead to longer development lead time. T The research conducted during the project was basically involving literature review, online journals review, questionnaire, case study, and discussion. This research covers the whole development process of the system, up to the implementation and evaluation. The result shows that there is improvement of 42.47% in delivering tracking information to the customers.
Where children and adolescents drown in Queensland: a population-based study

Objective This retrospective population-based study examined drowning location by the site of immersion for both fatal and non-fatal drowning events in Queensland. Drowning location is not routinely collected, and this study used data linkage to identify drowning sites. The resulting enhanced quality data quantify drowning incidence for specific locations by geographic region, age group and by severity for the first time. Design Linked data were accessed from the continuum of care (prehospital, emergency, hospital admission and death data) on fatal and non-fatal drowning episodes in children aged 0–19 years in Queensland for the years 2002–2008 inclusive. Results Drowning locations ranked in order of overall incidence were pools, inland water, coastal water, baths and other man-made water hazards. Swimming pools produced the highest incidence rates (7.31/100 000) for overall drowning events and were more often privately owned pools and in affluent neighbourhoods. Toddlers 0–4 years were most at risk around pools (23.94/100 000), and static water bodies such as dams and buckets—the fatality ratios were highest at these 2 locations for this age group. Children 5–14 years incurred the lowest incidence rates regardless of drowning location. Adolescents 15–19 years were more frequently involved in a drowning incident on the coast shoreline, followed by inland dynamic water bodies. Conclusions Linked data have resulted in the most comprehensive data collection on drowning location and severity to date for children in the state of Queensland. Most mortality and morbidity could have been prevented by improving water safety through engaged supervision around pools and bath time, and a heightened awareness of buckets and man-made water hazards around the farm home for young children. These data provide a different approach to inform prevention strategies.
A sensitive enzyme‐linked immunosorbent assay for determination of bovine β‐lactoglobulin in infant feeding formulas and in human milk

We developed a sensitive sandwich‐type ELISA for measuring low levels of cow's milk (CM) β‐lactoglobulin. Purified anti‐β‐lactoglobulin was used as coating antibody and also as second antibody conjugated with alkaline phosphatase. Polyethylene glycol 6000 was added to the incubation buffers to improve sensitivity. The detection limit of the assay was 0.002 μg/l, which is much better than sensitivities reported for other β‐lactoglobulin assays. The sensitivity was not impaired by the presence of other CM proteins. The recovery from breast milk was 93% and from the diluting buffer 127%. The coefficient of variation within day was 5–15% and between days 10%. One hour after oral intake of milk, P‐lactoglobulin could be detected in the breast milk of three mothers at concentrations of about 1–2 μg/l. Widely different concentrations of β‐lactoglobulin were measured in two protein hydrolysates based on CM whey and casein proteins; the observed concentrations were 200 and 0.0056 μg P‐lactoglobulinμ/g dry weight, respectively.
Comparative Study between Teaching Football with Oral and Oral/Graphic Verbalization

The aim of this study was to compare two methods of teaching using two different modalities of verbalization: oral and oral/graphic. We opted for a quantitative-comparative analysis of the pupils’ language typologies taken from oral and written productions of third secondary grade pupils who play football in a professional club (juniors of Olympic Kef, IInd league, 18 years old on average). The comparisons between the group proceeding to an oral verbalization versus the group using an oral/graphic one as well as intra-groups’ comparisons did not show clear significant differences. Despite of a statistical signification absence, we note that the two teams made a progress (increase in the number of played and conquered balls and the shots on target) especially during the last three sessions. Indeed, the debate of ideas is a process. It is relevant that the interaction between learning oral and graphic verbalization is more dynamic, whenever pupils verbalize orally and graphically, they are more motivated to learn.
Local descriptors robust to out-of-plane rotations

The process of matching local descriptors which are invariant to affine transformation is an interesting problem with many practical applications. Currently, many state-of-the-art approaches are robust to scale changes and in-plane rotations, but they are not dealing well with out-of-plane rotations. In order to solve this problem, we are proposing the method of simulated local deformations of the image patches, which improves the robustness of the local descriptors in the mentioned problem. By performing rotations locally and then storing descriptors of these rotated patches, one obtains a richer representation, which results in better matching. We tested our method on a publicly available dataset of deformable objects and obtained improved matching results. In future studies, we are aiming at optimising this approach through parallel computing.
p27/kip1 expression in normal epithelium, benign and neoplastic breast lesions

The development of cancer in the breast and in other sites is a complex process requiring a number of different genetic and epigenetic alterations. The accumulation of the genetic changes is thought to underlie the progression from precancerous lesions to carcinomas. The expression of p27/kip1 protein, a cyclin‐dependent kinase inhibitor, was investigated by immunohistochemistry in normal epithelial specimens, benign alterations, and malignant lesions of the breast. The number of p27/kip1‐positive cells ranged from none to more than 98% in the overall series. Wide ranges of p27/kip1‐positive cells were consistently observed within each histological category, but the median value progressively decreased in typical hyperplasia and fibroadenoma, with an even more marked reduction in malignant lesions, compared with normal epithelium. Moreover, the percentage of cells expressing p27/kip1 in tumours was about three times lower in invasive than in in situ lesions and was inversely related to tumour size, but not to lymph node involvement. In conclusion, the degree to which p27 expression is altered in typical hyperplastic lesions and fibroadenomas indicates that the deregulation of p27 may occur very early on during breast cell transformation, but the usefulness of its determination to categorize subgroups of lesions at different risk of evolution remains somewhat doubtful. Copyright © 2001 John Wiley & Sons, Ltd.
High-performance discrete amplifier based on a second-order fiber Raman oscillator

We propose a second-order counterpumped Raman ring fiber oscillator for high gain and low noise discrete Raman amplification with enhanced robustness to wavelength-division-multiplexing channels add-drop operations. Bit-error-rate measurement at 10 Gb/s shows negligible penalties up to 20-dB net gain.
Cognitive impairment and depression among Chinese nonagenarians/centenarians.

PURPOSE In this study, we explored the association between cognitive impairment and depression in the very elderly using a sample aged 90-108 years. METHODS A cross-sectional study. RESULTS The sample included 682 unrelated Chinese nonagenarians/centenarians (67.25% women, mean age of 93.49 years). The mean depression score (measured with the brief 23-item Geriatrics Depression Scale-Chinese Edition was 8.45 (standard deviation [SD] = 3.30). The mean of cognitive function scores (measured with the 30-item Mini-Mental State Examination) was 15.54 (SD = 5.38). There was no significant difference in cognitive function scores between subjects with and without depression, and there was also no significant difference in depression scores between subjects with and without cognitive impairment. There was also no significant difference in the frequency of depression between subjects with and without cognitive impairment or in the frequency of cognitive impairment between subjects with and without depression. Both the odds ratio (OR) of depression (as a function of increased cognitive impairment) and the OR of cognitive impairment (as a function of increased depression) were found to be insignificant. Pearson Correlation also showed no significant correlation between depression scores and cognitive function scores. CONCLUSIONS In summary, we found that depression was not directly correlated with cognitive impairment in Chinese nonagenarians and centenarians.
Observations on the variability of the H reflex in human soleus

H reflexes were evoked in human soleus by stimulating the tibial nerve at a constant intensity. Each trial was then assigned to one of three groups on the basis of the amplitude of its H reflex; all trials in each group were then full‐wave rectified and reaveraged. There was a strong positive relationship between the amplitude of the H reflex and the level of electromyographic activity in the muscle at the time of onset of the H reflex, which reflects the activity of the motoneuronal pool when the afferent volley arrived. Thus, much of the variability of the H reflex is due to small changes in the level of activation of the motoneuronal pool during repeated trials. The steady torque preceding the H reflex was a poor predictor of the H‐reflex amplitude, presumably because of the delay between the changes in the electrical activity of motoneurons and the mechanical outcome thereof. © 1999 John Wiley & Sons, Inc. Muscle Nerve 22: 341–346, 1999
Tweets, Apps, and Pods: Results of the 6-Month Mobile Pounds Off Digitally (Mobile POD) Randomized Weight-Loss Intervention Among Adults

Background Previous interventions have shown promising results using theory-based podcasts to deliver a behavioral weight-loss intervention. Objective The objective of our study was to examine whether a combination of podcasting, mobile support communication, and mobile diet monitoring can assist people in weight loss. Methods In this 6-month, minimal contact intervention, overweight (n = 96, body mass index 32.6 kg/m2) adults were recruited through television advertisements and email listservs and randomly assigned to Podcast-only or Podcast+Mobile groups. Both groups received 2 podcasts per week for 3 months and 2 minipodcasts per week for months 3–6. In addition to the podcasts, the Podcast+Mobile group was also instructed to use a diet and physical activity monitoring application (app) on their mobile device and to interact with study counselors and other participants on Twitter. Results Weight loss did not differ by group at 6 months: mean –2.7% (SD 5.6%) Podcast+Mobile, n = 47; mean –2.7% (SD 5.1%) Podcast, n = 49; P = . 98. Days/week of reported diet monitoring did not differ between Podcast+Mobile (mean 2.3, SD 1.9 days/week) and Podcast groups (mean 1.9, SD 1.7 days/week; P = .28) but method of monitoring did differ. Podcast+Mobile participants were 3.5 times more likely than the Podcast group to use an app to monitor diet (P = .01), whereas the majority of Podcast participants reported using the Web (14/41, 34%) or paper (12/41, 29%). There were more downloads per episode in the Podcast+Mobile group (1.4/person) than in the Podcast group (1.1/person; P < .001). The number of podcasts participants reported downloading over the 6-month period was significantly moderately correlated with weight loss in both the Podcast+Mobile (r = –.46, P = .001) and the Podcast (r = –.53, P < .001) groups. Podcast+Mobile participants felt more user control at 3 months (P = .02), but not at 6 months, and there was a trend (P = .06) toward greater elaboration among Podcast+Mobile participants. There were significant differences in reported source of social support between groups. More Podcast participants relied on friends (11/40, 28% vs 4/40, 10%; P = .045) whereas Podcast+Mobile participants relied on online sources (10/40, 25% vs 0/40; P = .001). Conclusions Results confirm and extend previous findings showing a minimally intensive weight-loss intervention can be delivered via podcast, but prompting and mobile communication via Twitter and monitoring app without feedback did not enhance weight loss. Trial Registration Clinicaltrials.gov NCT01139255; http://clinicaltrials.gov/ct2/show/NCT01139255 (Archived by WebCite at http://www.webcitation.org/625OjhiDy)