Miracle-dz/UniFAR-FTUs huggingface dataset:
Awareness of dental implant treatment in an Indian metropolitan population

Introduction: As implant dentistry becomes popular with each passing, need to understand its awareness in the general population exists. The aim of this study was to assess the public awareness of dental implants as a treatment option and its demographic distribution in the Indian Metropolitan City of Mumbai. Materials and Methods: A questionnaire-based survey consisting of 12 questions on implant treatment awareness was conducted on randomly selected 1000 individuals attending eight dental clinics in the city of Mumbai, India. Distribution for each question was assessed using frequencies and percentages for various sociodemographic groups. Results: 32.30% of the participants were aware of dental implants as an option to replace missing teeth, without significant variance in gender and age groups ranging from 18 to 70 years. Awareness of dental implant treatment increased with the increase in socioeconomic status. Dentists were the main source of information on implants, followed by the internet. 46.8% of the participants wanted additional information on dental implants. Among those aware of implants, 62.85% of the participants regarded high cost of the treatment as the biggest disadvantage, 31.89% of the participants blamed their dental professional for the failure of implants, 48.92% of the participants thought implants would last a lifetime, and 85.45% of the participants were ready to restore their missing teeth with implant-based treatment options. Conclusion: This study reveals that there is a lack of awareness of dental implants and implant-based treatment in the population, especially in those with a low socioeconomic status. However, a significant portion of the population wanted to have more information on dental implants. Special efforts to improve doctor-patient communications will be needed to bridge the information gap.
Electrostatic devices related to pneumatic conveying of powders. A short literature review

Abstract Pneumatic conveying is one of the industrial processes that give the most electrical charge to divided solids. This electrical charge is generally a nuisance that can, for example, influence the flowability, create discharges or even explosions in the ducts. In order to counteract these tribocharging phenomena, which are not well apprehended, several authors designed and implemented different measurement devices for the measurement of powder tribocharging in pneumatic conveying. In this article, we present an overview of four such devices. The first one has been based on a loop operation principle using Teflon particles convoyed with azote. According to the process of powder coating, a second was elaborated. A third was developed to confront several parameters that influence tribocharging in pneumatic conveying. The latest apparatuses presented here have been improved to carry out more reliable tests.
Measuring Urban Spatial Activity Structures: A Comparative Analysis

Human activity recognition has been of interest in the field of urban planning. This paper established a general framework by which expected human activity intensity (HAI) measured by the built environment and factual HAI measured by the Baidu thermal chart were estimated and comparatively analyzed so as to identify abnormal human activities in Hanghzou, China. Three elements of the built environment (i.e., residential density, road connectivity, and land-use mixing degree) from multi-source data with high precision are selected to assess the expected HAI. Results indicate Hangzhou has evolved into a polycentric city with three urban clusters. In addition, a significant positive correlation exists between the two types of HAIs. However, there are areas with spatial mismatches, particularly in the “urban village” and new towns, suggesting human activities are not equally distributed all over the city. Research implications, limitations, and future research needs are discussed.
Mobile App Usage Patterns Aware Smart Data Pricing

The explosive growth of traffic-consumption by mobile devices is leading to severe cellular network congestion, which is posing challenges for Internet Service Providers (ISPs) to provide good quality services with limited cellular capacity and impacting the user’s experience. Data pricing has been proven to be an effective way to enhance both the service quality and ISP’s profit. However, traditional data pricing schemes do not consider the real Mobile Application (App) Usage Patterns (MAUPs) among large scale cellular networks. In this paper, MAUPs aware smart data pricing scheme is proposed. In our work, we firstly extract and model the users’ app usage behaviors of approximately 9,600 cellular towers as two-dimensional MAUPs (time, app category). Then 7 distinct derived MAUPs are considered to be incorporated into the user satisfaction model and ISP’s profit model. The performance of our proposal is evaluated and verified by numerical experiments from the aspects of ISP’s profit, consumption surplus, capacity utilization and traffic efficiency. The MAUPs based pricing scheme can be periodically updated according to the operational conditions and therefore significantly instructive for ISPs.
An Automatic Method for Water Extraction From High Spatial Resolution GF-1 Imagery Based On A Deep Learning Algorithm

Traditional remote sensing methods for water extraction generally rely on complex spectral analysis and subjective thresholds, which do not satisfy the requirements for automated high-accuracy water detection from high spatial resolution images. In this paper, a novel framework of Convolutional Neural Networks (CNNs) is proposed for automatic water extraction based on Densely Connected Convolutional Networks (DenseNet) and a U-net structure. The proposed CNN model is trained on 1300 GF-1 images and tested on another 50 GF-1 images. Six of the GF-1 images are used for experiments to demonstrate the accuracy of the results and compare them with those from NDWI and supervised classification methods. The results show that our method has better computation efficiency and classification accuracy. The new framework has remarkable advantages for automatic water extraction from high-resolution images, especially in maintaining the integrity of small water bodies and in overcoming interference from clouds, shadows in built-up-areas, and mountainous areas with snow cover.
Rural Household Livelihood and Tree Plantation Dependence in the Central Mountainous Region of Hainan Island, China: Implications for Poverty Alleviation

Plantations support local economies and rural livelihoods in many mountainous regions, where poverty and a fragile environment are often interlinked. Managing plantations sustainably and alleviating poverty is a major challenge. This study reports on the findings of a household livelihood survey in the central mountainous region of Hainan Island, a global biodiversity hotspot. The survey aimed to identify rural household livelihoods, strategies to lift rural households out of poverty and potential environmental consequences of different livelihood strategies. Households were divided into five groups based on their main source of income: plantations, crops, livestock, local off-farm income and remittances. Plantations were the main source of income for 74% of households and provided 46% of the total income. Plantation land area, planting diverse tree species and intercropping were significantly associated with higher income. Reallocating land by family size could increase the proportion of households above the poverty line in the plantation group from 51.3% to 85.3%, while making only 3.3% of households worse off. Lower income households tended to apply more chemicals to plantations, which suggests that they create more strain on the environment. Improving household income through dynamically allocating plantation land and diversifying planted species could therefore be beneficial both socially and environmentally. Our results emphasize the importance of dynamic plantation land allocation and diverse plantation planting in poverty alleviation and environmental sustainability.
Genetic risk factors for movement disorders in Finland

Parkinson’s disease and Huntington’s disease are progressive neurodegenerative movement disorders that typically manifest in adulthood. In this study, genetic risk factors contributing to these two movement disorders were investigated in Finnish patients. Patients with early-onset or late-onset Parkinson’s disease as well as population controls were examined. The p.L444P mutation in GBA was found to contribute to the risk of Parkinson’s disease. POLG1 compound heterozygous mutations were detected in two patients with Parkinson’s disease and rare length variants in POLG1 were associated with Parkinson’s disease. Variants in SMPD1, LRRK2 or CHCHD10, previously detected in other populations, were not detected, suggesting that they are rare or even absent in the Finnish population. Patients with Huntington’s disease were investigated for HTT gene haplotypes as well as whether these haplotypes alter the stability of the elongated CAG repeat. Haplogroup A was less common in Finns than in other European populations, whereas it was significantly more common in patients with Huntington’s disease than in the general population. Certain HTT haplotypes as well as the parental gender were found to affect the repeat instability. We found that compound heterozygous mutations in POLG1 were causative of Parkinson’s disease, rare length variants in POLG1 were associated with Parkinson’s disease and GBA p.L444P was significantly more frequent in patients than in the controls, which suggests that these mutations are associated with the development of Parkinson’s disease. The low prevalence of Huntington’s disease in Finland correlates with the low frequency of the disease-associated HTT haplogroup A. Paternal inheritance combined with haplotype A1 increased the risk of repeat expansion. Movement disorders in Finland were found to share some of the same genetic risk factors found in other European populations, but some other recognized genetic variants could not be detected.
Three Artificial Spintronic Leaky Integrate-and-Fire Neurons

Due to their nonvolatility and intrinsic current integration capabilities, spintronic devices that rely on domain wall (DW) motion through a free ferromagnetic track have garnered significant interest in the field of neuromorphic computing. Although a number of such devices have already been proposed, they require the use of external circuitry to implement several important neuronal behaviors. As such, they are likely to result in either a decrease in energy efficiency, an increase in fabrication complexity, or even both. To resolve this issue, we have proposed three individual neurons that are capable of performing these functionalities without the use of any external circuitry. To implement leaking, the first neuron uses a dipolar coupling field, the second uses an anisotropy gradient and the third uses shape variations of the DW track.
Therapeutic dual inhibition of HER2 pathway for metastatic colorectal cancer (mCRC): The HERACLES trial.

565 Background: HER2 amplification in mCRC associates with resistance to anti-EGFR moAbs and, based on studies in patient-derived xenografts (Bertotti et al, Cancer Discov 2011), predicts response to combined therapy with anti-HER2 moAbs and lapatinib (L). Accordingly, we conducted an independent proof-of-concept phase II study of trastuzumab (T) and L in HER2+ mCRC after failure of standard therapies (HERACLES Trial - EudraCT 2012-002128-33). Methods: mCRC patients (pts) progressing after fluoropyrimidines, oxaliplatin, irinotecan, bevacizumab, and cetuximab or panitumumab were eligible if tumors were HER2+ [IHC 3+ or 2+ and FISH positive (HER2:CEP17 >2) in >50% cells]. L was given po daily and T iv weekly at standard doses. Tumor response was assessed every 8 weeks. The primary end-point was objective response (OR, RECIST v1.1). To consider the study positive 6/27 ORs had to be observed (α=0.05; β=85%; H1=30%). Serial liquid biopsies for ctDNA (ddPCR), and HER2 ectodomain (ECD) plasma levels (ELISA) wer.
Differential contributions of synaptic and intrinsic inhibitory currents to speech segmentation via flexible phase-locking in neural oscillators

Current hypotheses suggest that speech segmentation – the initial division and grouping of the speech stream into candidate phrases, syllables, and phonemes for further linguistic processing – is executed by a hierarchy of oscillators in auditory cortex. Theta (~3-12 Hz) rhythms play a key role by phase-locking to recurring acoustic features marking syllable boundaries. Reliable synchronization to quasi-rhythmic inputs, whose variable frequency can dip below cortical theta frequencies (down to ~1 Hz), requires “flexible” theta oscillators whose underlying neuronal mechanisms remain unknown. Using biophysical computational models, we found that the flexibility of phase-locking in neural oscillators depended on the types of hyperpolarizing currents that paced them. Simulated cortical theta oscillators flexibly phase-locked to slow inputs when these inputs caused both (i) spiking and (ii) the subsequent buildup of outward current sufficient to delay further spiking until the next input. The greatest flexibility in phase-locking arose from a synergistic interaction between intrinsic currents that was not replicated by synaptic currents at similar timescales. Our results suggest that synaptic and intrinsic inhibition contribute to frequency-restricted and - flexible phase-locking in neural oscillators, respectively. Their differential deployment may enable neural oscillators to play diverse roles, from reliable internal clocking to adaptive segmentation of quasi-regular sensory inputs like speech. Author summary Oscillatory activity in auditory cortex is believed to play an important role in auditory and speech processing. One suggested function of these rhythms is to divide the speech stream into candidate phonemes, syllables, words, and phrases, to be matched with learned linguistic templates. This requires brain rhythms to flexibly phase-lock to regular acoustic features of the speech stream. How neuronal circuits implement this task remains unknown. In this study, we explored the contribution of inhibitory currents to flexible phase-locking in neuronal theta oscillators, believed to perform initial syllabic segmentation. We found that a combination of specific intrinsic inhibitory currents at multiple timescales, present in a large class of cortical neurons, enabled exceptionally flexible phase-locking, suggesting that the cells exhibiting these currents are a key component in the brain’s auditory and speech processing architecture.
Discuss The Use Of Oncolytic Viruses As Cancer Therapeutics

Cell death by oncolytic viruses occurs through direct or indirect mechanisms such as amplification of anti-cancer immune response, tumor blood vessels destruction or through transgene-encoded proteins manifested from modified viruses. Despite the different mode of action, the ultimate function of the oncolytic viruses is to disrupt the cancer cells’ transcriptional or
Non-invasive Determination of Bone Perfusion in Jaw AugmentationâAPilot Study

Introduction: Autologous bone transplantation is a standard procedure in dentoalveolar surgery for filling bone defects prior to implant placement. Information about bone perfusion is essential in the assessment of bone donor and recipient sites. A valid assessment of tissue microcirculation is possible without applying an invasive technique. Until now, it has been impossible to measure bone perfusion as part of a non-invasive procedure. Materials and Methods: Bone perfusion was determined for two augmentation procedures, both during the procedure and three months later. In one case, the graft and the recipient site were measured (mental bone graft), in the other, measurements were taken only at the time of augmentation (pelvic bone graft). It was measure in 2mm depth the relative blood flow, the venous oxygen saturation of haemoglobin and the regional haemoglobin concentration Results: Flow, SO2 and rHb could be determined about the whole course of the intervention. Above all the comparison between the augmentation and the control after 3 months could occur. The values were consistent with the clinical situation and allowed an assessment of perfusion. Conclusion: The measurements taken on the two patients have shown that the probe is well suited to measure local circulation in bones. It was possible to measure bone perfusion at all times. The method can be declared safe and practicable. It was demonstrated that this non-invasive method of measuring bone perfusion provides reproducible data that offer information on the perfusion of the graft and the recipient site at any time during the procedure and thus provide a valid assessment of vitality.
Identification of a Nonsense-Mediated Decay pathway at the Endoplasmic Reticulum

Nonsense-mediated decay (NMD) is a translation-dependent RNA quality control mechanism that occurs in the cytoplasm. However, it is unknown how NMD regulates the stability of RNAs translated at the Endoplasmic Reticulum (ER). Here, we identify a localized NMD pathway dedicated to ER-translated mRNAs. We previously identified NBAS, a component of the Syntaxin 18 complex involved in Golgi-to-ER trafficking, as a novel NMD factor. Here, we show that NBAS fulfils an independent function in NMD. This ER-NMD pathway requires the interaction of NBAS with the core NMD factor UPF1, which is partially localized at the ER in the proximity of the translocon. NBAS and UPF1 co-regulate the stability of ER-associated transcripts, in particular those associated with the cellular stress response. We propose a model where NBAS recruits UPF1 to the membrane of the ER and activates an ER-dedicated NMD pathway, thus providing an ER protective function by ensuring quality control of ER-translated mRNAs. Graphical Abstract HIGHLIGHTS NBAS is an NMD factor that localizes to the membrane of the endoplasmic reticulum (ER) NBAS has dual, independent, roles in Golgi-to-ER retrograde transport and in ER-NMD NBAS recruits the core NMD factor UPF1 to the membrane of the ER The ER-NMD pathway targets for degradation mRNAs that are translated at the ER
Effects of Allelochemical of Jatropha curcas L. Leachate on Germination and Shooting of Four (4) Pepper (Capsicum) Species in Keffi Nasarawa State, Nigeria

A laboratory study was carried out to evaluate the effect of leaf aqueous extract of Jatropha curcas L. on germination and early shoot growth of four pepper (Capsicum) species at the Department of Plant Science and Biotechnology Laboratory, Nasarawa State University, Keffi, Nigeria. Data collected were percentage inhibition and shoot length. Results from the experiment indicated that there was significant difference between the treatments (4%, 8%, 12%, 16% and 20%) and the control (0%) and within the treatments at P ≤ 0.05. All the test crops were affected by different concentrations of the aqueous extracts and the most pronounced effect was at 12%, 16% and 20% concentrations of the extracts in all cases respectively. Germination, shooting were inhibited completely at higher concentrations in the cases when compared with the control. The inhibitory effect was found to be concentration dependent and may be due to the presence of water soluble allelochemicals like phenols, tannins and azeliac acid.
PARTICULARITE DES SYNDROMES CORONARIEN AIGUE CHEZ LA FEMME, EXPERIENCE DU SERVICE DE CARDIOLOGIE DE LHOPITAL MILITAIRE AVICENNE MARRAKECH

A. Chetoui, I. Benamar, L. Bendriss and A. Khatouri Service De Cardiologie Et Maladies Vasculaires Hôpital Militaire Avicenne De Marrakech. Manuscript Info Abstract . Manuscript History Received: 30 November 2019 Final Accepted: 31 December 2019 Published: January 2020
Herbs that heal Spices: The hoard of natural remedies

Plants and humans have cherished a great association ever since their beginning of this planet. Our planet is called green planet just because of the green boon given to us by Mother Nature. Plants fulfill almost every need of humans and other life present on this planet. Through finely woven ecosystems with well formed trophic levels, humans are getting precious offering in the form of plants, including their food, feed, shelter and most significantly the medicines to cure various ailments. In this review an attempt has been made to highlight just only three common kitchen’s spices that have valuable aspects as medicinal herbs, viz., Cinnamomum verum J. Presl (Dalchini), Trigonella foenum-graecum L. (Methi) and Crocus sativus L. (Kesar). An all inclusive account of these three is given related to their potential as natural medicines.
Stacked lossless deconvolutional network for remote sensing image restoration

Abstract. Satellite image restoration from its degraded observation has a significant impact on the remote sensing industry. There are many potential applications that can directly benefit from this technique. A convolutional neural network (CNN) has been recently explored in image restoration and achieved remarkable performance. However, most deep CNN architectures in the literature do not properly handle the inherent trade-off between localization accuracy and the use of global context, which is vital for satellite images covering a ultrabroad area. We present a stacked lossless deconvolutional network (SLDN) for remote sensing image restoration. We fully exploit global context information while guaranteeing the recovery of fine details. Specifically, we design a lossless pooling by reformulating the pixel shuffle operator and incorporate it with a shallow deconvolutional network. The resulting lossless deconvolution blocks are stacked one by one to enlarge the receptive fields without any information loss. We further propose an attentive skip connection and progressive learning scheme to improve gradient flows throughout the SLDN. The SLDN can reconstruct high-quality satellite images without noticeable artifacts. An extensive ablation study is also provided to show that all the components proposed are useful for remote sensing image restoration. Experimental comparisons on various restoration tasks, including super-resolution, denoising, and compression artifact reduction, demonstrate the superiority of the proposed method over state-of-the-art methods both qualitatively and quantitatively.