Miracle-dz/UniFAR-FTUs huggingface dataset:
A Method to Support the Alignment of Business Models and Goal Models

This paper addresses one part of business and IT-alignment by proposing a method to align goal models and business models. The method takes as input a goal model and a business model, and outputs a business model that is aligned with the explicit goals of a business actor. The method builds on previous work with the same approach but extends that work in at least two ways: the syntax of some method constituents is altered and a way to combine them is introduced. The result is an improved method that better support a modeller when designing business models based on goal models.
Keeping it Personal

I never imagined I would make wine for a living, create a business from what started as a backyard hobby. It all began quite by chance. I studied insurance at the Institute of Finance Management and became an insurance broker. I worked for the National Insurance Company in the early days of my career but because I had aspirations to become a businessman, I knew I would learn more in the private sector. The wine was a hobby, a friend introduced me to it and whilst I dismissed it as a business concept – who would want to drink banana wine, I asked myself – I thought I would try making some just for our own consumption at home. Visitors and family enjoyed it but then I found too many visitors enjoying it so I stopped giving it away and instead began to sell it. In 1993 my wife and I bought a small plot of land just outside Arusha, andwe constructed a little factory and registered the business formally –my wife and I remain the primary shareholders. To our surprise, the wine business grew and grew to the point where we were obliged to sell our other businesses – an insurance agency and a tour company – and concentrate on developing a commercial local wine business – we target lower income consumers. And, a little over 20 years later, our expected turnover this year is $5 million. I expect to double production in the next five years; we have been expanding volumes at a rate of 10% per annum. Today we produce gin and bottled water (our newest addition) as well as the original banana wine and we employ 180 full-time members of staff and 150 temporary workers. My wife remains completely involved in an operational capacity: she keeps an eye on different departments, ensuring procedures between them run smoothly, she checks performance reports and manages sales, invoicing, stock – she is very hands on and has a
Micromagnetic models for high-temperature magnetization dynamics

Recientemente, se han descubierto sorprendentes fenomenos en materiales magneticos como son la dinamica magnetica ultrarrapida y el efecto spin Seebeck con un gran interes tecnologico que va desde la grabacion magnetica a la espintronica. Para el desarrollo de aplicaciones tecnologicas basadas en estos nuevos procesos es necesario por un lado modelos micromagneticos que permitan reproducir en simulaciones computacionales el comportamiento magnetico a gran escala de dichos procesos, y por otro lado, es necesario tambien un mayor conocimiento sobre los mecanismos microscopicos responsables de los mismos. Los modelos micromagneticos basados en la ecuacion de Landau-Lifshitz-Gilbert (LLG) son muy utilizados en la modelizacion de materiales magneticos ya que en la mayoria de situaciones describen correctamente el comportamiento magnetico de dichos materiales, y por tanto, estos modelos son una herramienta muy util para el diseno de aplicaciones tecnologicas en las que se emplean materiales magneticos. En la ecuacion de LLG la magnitud de la magnetizacion promedio en un pequeno volumen del material (del orden de nanometros cubicos) es constante. Sin embargo, existen ciertos procesos como, por ejemplo, aquellos que tienen lugar a temperaturas cercanas a la temperatura de Curie en los que la ecuacion de LLG no puede reproducir correctamente el comportamiento observado experimentalmente. Esto es debido a que a altas temperaturas las ondas de espin de alta frecuencia (baja longitud de onda) juegan un papel muy importante en el comportamiento magnetico. Por otro lado, la magnitud de la magnetizacion promedio en un pequeno volumen de material no es constante a estas temperaturas. Generalmente, estos nuevos procesos tienen lugar a altas temperaturas, por tanto, es necesario el desarrollo de modelos micromagneticos, alternativos a aquellos basados en la ecuacion de LLG, que puedan describirlos correctamente. Una posible alternativa a la ecuacion de LLG es la ecuacion de Landau-Lifshitz-Bloch (LLB) desarrollada por D. Garanin, ya que es mas termodinamicamente consistente que la ecuacion de LLG. La ecuacion de LLB contiene un termino que proviene del canje interno del material y describe la dinamica longitudinal magnetica, y por tanto, puede describir correctamente los procesos magneticos a altas temperaturas y tiempos cortos. En esta tesis proponemos un modelo micromagnetico basado en la version cuantica de la ecuacion de LLB tanto para materiales ferromagneticos como aleaciones magneticas. Ademas, esta ecuacion debido a su naturaleza cuantica permite analizar teoricamente como diferentes mecanismos microscopicos afectan a la dinamica magnetica lo que podria ayudar a entender mejor el origen de estos nuevos procesos.
The role of EphA7 and its binding partner ephrinA5 in angiogenesis

Angiogenese bezeichnet die Entstehung von neuen Blutgefassen aus dem bereits bestehenden Netzwerk und stellt somit einen Schlusselmechanismus fur Entwicklung und Wachstum dar. Ephrine und ihre dazugehorigen Eph-Rezeptoren stellen eine der vier Familien von „Guidance-Molekulen“ fur Axone dar, die auch eine sehr wichtige Rolle in der vaskularen Entwicklung und der Differenzierung zwischen Arterien und Venen spielen. Sie bilden die grosste Familie von Rezeptor-Tyrosin-Kinasen und verursachen durch komplexe Interaktion mit anderen Signalmolekulen und Signaltransduktionswegen eine biologische Antwort mit zwei unterschiedlichen Folgen- Repulsion oder Attraktion von Zellen. Die Eph-Ephrin Signalgebung wurde bereits in verschiedensten Aspekten untersucht, unter anderem in neuronalen Zellen, und wurde als potentielle Anti-Tumor Therapie eingestuft. Das Ziel dieser Arbeit war es, die Reaktion von Endothelzellen auf EphrinA5-EphA7 Signalgebung bezuglich Migration und Proliferation zu untersuchen. Nachdem fruhere Untersuchungen gezeigt haben, dass EphrinA5-EphA7 Expression zu Repulsion von neuronalen Zellen fuhrt, wurden ahnliche Antworten in Endothelzellen erwartet. Die Schwerpunkte der Experimente stellten das Generieren von Ephrin-Fc und monomerischen Ephrin Konstrukten und deren Einsatz in funktionellen Tests mit HUVEC (human umbilical venous endothelial cells) dar. Diese basierten auf dem Vorwissen, dass EphrinA7 ein Zielgen des Transkriptionsfaktors SOX18 ist. Durch transiente Transfektion von HUVEC mit SOX18-IRES/GFP wurde die Expression von EphA7 ausgelost. HUVEC, die mit SOX18/GFP transient transfektiert wurden, reagierten mit Retraktion auf die Konfrontation durch mit Antikorper geclustertem EphrinA5-Fc. Ein weiterer Ansatz, in dem Zellen mit SOX18/GFP Adenovirus infiziert und EphrinA5-Fc, das mit Protein G Polystyrene Kugeln geclustert wurde, ausgesetzt wurden, fuhrte zu keiner Reaktion. In einem in vitro Wundheilungsversuch, in dem EphrinA5-Fc Fusionskonstrukte, EphrinA5 Monomere und Kontroll-Fc verwendet wurden, wurden keine signifikanten Ergebnisse erzielt. Zusammenfassend kann man sagen, dass es sich bei den erzielten Daten um die ersten Schritte handelt, um die Rolle von EphA7 in Endothelzellen besser zu beleuchten, die in zukunftigen Studien weiterverfolgt werden sollten.
THE TREATMENT OF DEFORMITIES OF THE SPINE CAUSED BY POLIOMYELITIS: A REPORT OF EIGHT CASES IN WHICH FUSION OPERATIONS WERE PERFORMED

Deformities which develop in consequence of permanent damage to the muscles of the spine from anterior poliomyelitis are among the most difficult with which the orthopedic surgeon has to deal, and I know of no means which can be depended on to prevent their progress. Plaster jackets and braces can, at best, only retard the development of deformity. It has seemed to me practical, therefore, in such cases, to do a fusion operation on the spine exactly similar to that which has been used in the treatment of Pott's disease at the Orthopaedic Hospital since 1910. It is my purpose to report eight cases in which this operation has beendone for scoliosis. None of these patients were operated on until long after the acute attack, and obviously one would not operate at all if there were any prospect of recovery of the muscles affected. I do not think, however, it
Identification and Treatment of Congenital Muscular Torticollis in Infants

Torticollis is a clinical sign or symptom that could be the result of a variety of underlying disorders. Congenital muscular torticollis (CMT) is a postural deformity detected at birth or shortly after birth, primarily resulting from unilateral shortening and fibrosis of the sternocleidomastoid muscle (SCM). Infants with CMT display head tilt to one side, which is often combined with rotation of the head to the opposite side (Figure 1). CMT is estimated to occur in one infant of every 300 live births. Plagiocephaly is reported as a coexisting impairment in 80% to 90.1% of children with CMT. The purposes of this report are to provide an overview of the CMT literature with attention to the relationship between torticollis and plagiocephaly and to describe current management of infants with congenital muscular torticollis with or without plagiocephaly. CMT with impairment of the SCM is the most frequent cause of torticollis in infants, but torticollis could also be the result of other underlying disorders. The congenital and developmental causes of torticollis in children have been classified as osseous, nonosseous, or neurogenic (Table 1). The prevalence of nonmuscular causes of torticollis in children could be as high as 18%. Children with ocular torticollis could present with the postural signs of torticollis without restrictions in cervical range of movement. The child with impairment of extraocular muscles in one eye could tilt or turn the head to achieve a clear binocular view. Paresis of the superior oblique muscle could result in head tilt away from the side of impairment and is the most common source of ocular torticollis. The pathophysiology and etiology of sternocleidomastoid impairment in CMT is still unknown. Prominent theories related to the cause of sternocleidomastoid impairment in CMT include intrauterine crowding, muscle trauma during a difficult delivery, soft tissue compression leading to compartment syndrome, and congenital abnormalities of soft tissue differentiation within the SCM muscle. Children with CMT can be assigned to one of three clinical subgroups: 1) children with a palpable swelling or pseudotumor of the sternocleidomastoid, 2) children with SCM tightness but no tumor, and 3) children with all the features of muscular torticollis without muscle tightness or tumor. In an alternative system of classification, pseudotumor of infancy and CMT are described as separate diagnoses.
Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis

Introduction: In previous decades, the analysis of heart rate variability (HRV) provided a non-invasive method of assessing autonomic influence for cardiovascular risk stratification. The aim of this study was to determine whether HRV analysis can still perform a similar function in the present day. Material and methods: The study group consisted of 113 patients with acute myocardial infarction (AMI) treated with thrombolysis. In all patients echocardiography on the 10 th day after myocardial infarction and 24-h Holter electrocardiographic recordings on the 12 th day after myocardial infarction were performed. Five time domain measures were calculated from the time series of normal N-N intervals: SDNN, SDANN index, SDNN index, rMSSD and pNN50. The end points in follow-up were: death, non-fatal myocardial infarction (AMI) and unstable angina pectoris requiring hospitalization (API). The study group was divided into two subgroups on the basis of SDNN value and both groups were analysed. Results: At follow-up (mean 65 months, range 36 to 96 months) we observed clinical events in 44 patients, including 17 deaths, 8 cases of AMI and 20 cases of API requiring hospitalization. In the multivariate analysis SDNN ≤ 70 ms as well as left ventricle ejection fraction < 30% were independent predictors of death. Conclusions: SDNN ≤ 70 ms remains a significant predictor of death in patients with MI treated with thrombolysis.
Global Clinical Symptom Spectrum in Gastroesophageal Reflux Disease

Operational definitions of gastroesophageal reflux disease (GERD) reflect that the term covers a wide spectrum of clinical conditions, ranging from symptomatic syndromes to local or systemic complications, which result from gastroesophageal reflux of gastric content. The majority of GERD patients experience heartburn and acid regurgitation, which are considered to be typical reflux symptoms. However, a considerable number of patients with GERD have no or nondominant typical symptoms but report nontypical gastrointestinal symptoms or present with extraesophageal syndromes, like noncardiac chest pain, broncho-pulmonary and ENT manifestations, or sleep-related alterations. Reasons to base the definition of GERD on symptoms are the high prevalence of GERD patients in primary and secondary care without overt mucosal damage [nonerosive reflux disease (NERD)], the suboptimal sensitivity and specificity of technical measures, and the close association between impairment in quality of life and symptom load in erosive GERD (eGERD) and NERD. Symptom characteristics (ie, intensity, frequency, and symptom pattern) in GERD patients are of limited value in clinical practice to predict the severity of lesions and are useless to differentiate between subjects suffering from eGERD or NERD. Also, typical symptoms, like heartburn and acid regurgitation, have limited sensitivity and specificity compared with technical measures, like esophageal pH-metry, and the accuracy of diagnosis based on these symptoms is unsatisfactory. Among other reasons, this is due to widespread occurrence of nontypical symptoms in GERD patients, phasic courses of the disease, and overlap of GERD with other entities, like functional dyspepsia and irritable bowel syndrome. Thus, one should consider GERD also if atypical symptoms are present, and outcome criteria in GERD treatment trials should recognize the broad spectrum of symptoms in GERD. This is feasible with the ReQuest, a questionnaire considering typical and atypical symptoms, which has been validated in patients with eGERD and NERD. Probatory proton pump inhibitor treatment can be helpful to identify typical and atypical symptoms related to gastroesophageal acid reflux in selected patients.
Enfermedades crónicas y limitación funcional en adultos mayores: estudio comparativo en siete ciudades de América Latina y el Caribe

OBJETIVO: Identificar la relacion entre determinadas enfermedades cronicas y la presencia de discapacidad en habitantes de 60 anos o mas de siete centros urbanos de America Latina y el Caribe que participaron en el estudio multicentrico Salud, Bienestar y Envejecimiento (SABE). METODOS: En 2000 y 2001 se realizo un estudio descriptivo de corte transversal con una muestra de 10 891 personas de 60 anos o mas que residian en siete ciudades de la Region: Bridgetown, Barbados; Buenos Aires, Argentina; Ciudad de La Habana, Cuba; Mexico, D.F. , Mexico; Montevideo, Uruguay; Santiago, Chile, y Sao Paulo, Brasil. Las variables dependientes fueron la dificultad para realizar actividades basicas y actividades instrumentales de la vida diaria (ABVD y AIVD, respectivamente). Las variables independientes, recopiladas mediante autoinforme, fueron la edad, el sexo, el nivel educacional, el vivir solo o acompanado, la evaluacion de la propia salud y la presencia o no de hipertension arterial, diabetes mellitus, cancer, enfermedad pulmonar obstructiva cronica, cardiopatia isquemica (CI), enfermedades cerebrovasculares (ECV) y artrosis. Se evaluo la presencia de depresion y deterioro cognoscitivo en los participantes y se calculo su indice de masa corporal. Para comparar el grado de influencia de las diferentes variables sobre la discapacidad, se calculo un coeficiente estandarizado para cada caso. RESULTADOS: Las variables que mostraron una asociacion directa con dificultades para realizar ABVD y AIVD en las ciudades estudiadas fueron: padecer de un mayor numero de enfermedades no transmisibles, de ECV o de artrosis, asi como tener mayor edad, ser mujer, evaluar la salud propia como mala, tener deterioro cognoscitivo y padecer de depresion. En general, las asociaciones mas fuertes se encontraron entre la dificultad para realizar AIVD, por un lado, y por el otro la depresion, mayor edad, la evaluacion de la salud propia como mala y la presencia de ECV, artrosis o deterioro cognoscitivo. CONCLUSIONES: Se ofrece por primera vez una descripcion sistematizada de la asociacion entre la presencia de discapacidad y de enfermedades cronicas no transmisibles en adultos mayores en America Latina y el Caribe. Como las dificultades de los adultos mayores para realizar AIVD son las primeras en aparecer, se deben establecer mecanismos de seguimiento que permitan detectar tempranamente este tipo de discapacidad.
Emoticon Use in Mobile Communications

Emoticons are defined as graphical representations of facial expressions used in textbased messages (Rezabek & Cochenouer, 1998). They were first introduced at Carnegie Mellon University in 1982 by Scott Fahlman in order to help his students identify portions of electronic text that he meant as a joke in his computer science course. Since then, emoticons have steadily increased in use and complexity as computer-mediated communication has become more pervasive. Mobile technologies, in particular, have allowed individuals to communicate electronically with their social network in a plethora of locations, whenever they have an opportunity, and on devices that fit into most pockets. What once started as basic facial expressions, such as the smiley :) and frowny :(, emoticons now encompass a wide variety of expressions that number in the hundreds (Gil, 2014). Although originally displayed using letters and punctuation marks, technological advances have allowed modern emoticons to also be selected and displayed as images. Additionally, standard word processing software systems, such as Microsoft Word, recognize emoticons in text when typed and automatically changes them to more illustrative icons (i.e., changing :) to ☺ without any user actions). The increased diversity in emoticons today has enriched mobile communication by allowing individuals to insert important contextual and emotional information which might otherwise be lost.
Analysis and implementation of interface for heterogeneous system

We designed asynchronous event logic library with 0.25 /spl mu/m CMOS technology and high-speed asynchronous FIFO operating at 1.6 GHz. Optimized asynchronous standard cell layouts and Verilog models are designed for top-down design methodology. A method for mitigating a design bottleneck when it comes to tolerate clock skew is described. This communication scheme using clock control circuits, which is used for freeing of synchronization failures, is analyzed and implemented. With clock control circuit and FIFO, we implemented high-speed 32 bit-interface chip for heterogeneous system. The size of the core is about 1.1 mm/spl times/1.1 mm.
Development of an hexapod biomicrorobot with Nafion-Pt IPMC microlegs

This paper presents an artificial locomotion servo-system for an insect like hexapod biomicrorobot (BMR). This servo-system, programmed with VHDL code, will act as a driver in a RISC architecture microcontroller to reproduce insect tripod walking. An overview of the robot control system, in accordance with the insect displacement principle, is demonstrated with timing parameters. A control algorithm of the six legs driving the robot in any direction versus pulse width modulation (PWM) is reviewed. BMR microlegs are built with cylindrical Nafion-Pt ionomeric polymer-metal composite (IPMC) that have 2.5 degrees of freedom. Specific fabrication process for one leg is exposed. Dynamic behavior and microleg characteristics have been measured in deionized water using a laser vibrometer. BMR current consumption is an important parameter evaluated for each leg. Hardware test bench to acquired measurement is presented. The purpose of this design is to control a BMR for biomedical goals like implantation in human body. Experimental results on the proposed legs are conclusive for this type of bioinspired BMR.
Topographical maps for detecting relevance fields in car interiors

Die jeweiligen Modelle unterschiedlicher Automobilhersteller unterscheiden sich immer weniger hin-sichtlich Technologie, Effizienz und Preis. Produktdesign ermoglicht es den Herstellern ihre Produkte von denen der Konkurrenz abzugrenzen und einen Wettbewerbsvorteil zu erlangen. Vor allem das Design des Fahrzeuginneren gestattet hier eine individualisierte und distinkte Gestaltung. Auserdem ist das Design des Interieurs ausschlaggebend fur die Interaktion zwischen Fahrer und Fahrzeug und damit das Fahrverhalten. Eine Eyetracking-Studie wurde durchgefuhrt um die Bereiche des Autoin-nenraums zu erkunden denen die Konsumenten am meisten Aufmerksamkeit schenken. Dabei ging es einerseits um die Wichtigkeit der Ausstattungselemente bei einer Evaluation des Innenraums im Kon-text eines potentiellen Autokaufs und andererseits um die Relevanz der Bereiche und Instrumente wahrend einer simulierten Autofahrt. Die Ergebnisse deuten darauf hin, dass Komponenten die fur das Steuern des Fahrzeugs wichtig sind, die Ruckmeldung uber das Fahrzeug und das Fahrverhalten geben und Komfort- und Unterhaltungsausstattung fur die Versuchspersonen die groste Relevanz zu haben scheinen. Wahrend der Fahrsimulation wurden vor allem die Elemente des Armaturenbretts, die Spiegel und das Display der Mittelkonsole betrachtet. Die Ergebnisse der Untersuchung bieten An-regungen fur weitere Designforschung und Hilfestellungen fur Designer bei der Gestaltung des Fahr-zeuginneren gemas den Bedurfnissen und Praferenzen der Konsumenten.
Processamento de dados em aquisição simultânea de EEG / IFRM

v LISTA DE ACRÓNIMOS E SIGLAS . vi LISTA DE SÍMBOLOS . vi CAPÍTULO 1 – INTRODUÇÃO . 1 CAPÍTULO 2 – ANATOMIA E FISIOLOGIA CEREBRAIS . 3 2.1 – O CÉREBRO . 3 2.2 – CÉLULAS DO SISTEMA NERVOSO . 4 2.3 – O POTENCIAL DE ACÇÃO . 5 2.4 – A SINAPSE . 6 CAPÍTULO 3 – EPILEPSIA . 8 3.1 – SINTOMATOLOGIA E CLASSIFICAÇÃO . 8 3.2 – TRATAMENTO DA EPILEPSIA . 10 CAPÍTULO 4 – ELECTROENCEFALOGRAFIA . 11 4.1 – CARACTERÍSTICAS DO EEG . 11 4.2 – TÉCNICAS DE REGISTO . 11 4.3 – LOCALIZAÇÃO DE FONTES. 13 CAPÍTULO 5 – IMAGEM POR RESSONÂNCIA MAGNÉTICA. 14 5.1 – PRINCÍPIOS FUNDAMENTAIS DA IMAGEM POR RESSONÂNCIA MAGNÉTICA. 14 5.2 – PROCESSAMENTO DA IMAGEM TRIDIMENSIONAL . 17 5.3 – IMAGEM FUNCIONAL POR RESSONÂNCIA MAGNÉTICA . 22 CAPÍTULO 6 – METODOLOGIA EXPERIMENTAL . 32 6.1 – CASOS CLÍNICOS . 32 6.2 – AQUISIÇÃO SIMULTÂNEA DE EEG/IFRM . 32 6.3 – PROCESSAMENTO DE DADOS . 34 6.4 – PARÂMETROS DA FUNÇÃO DE RESPOSTA HEMODINÂMICA . 36 CAPÍTULO 7 – RESULTADOS . 37 7.1 – FASE 1 – TIPO, INTENSIDADE E LOCALIZAÇÃO DAS RESPOSTAS . 37 7.2 – FASE 2 – CONCORDÂNCIA ENTRE REGIÕES COM ALTERAÇÕES BOLD . 44 7.3 – FASE 3 – ANÁLISE MÚLTIPLA DAS RESPOSTAS BOLD . 50 viii CAPÍTULO 8 – DISCUSSÃO DE RESULTADOS . 58 CAPÍTULO 9 – CONCLUSÃO E PERSPECTIVAS FUTURAS . 61 BIBLIOGRAFIA . 63 ANEXOS . 67