Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards Scalable Emotion Classification in Microblog : How to Make Use of Noisy Training Data

The availability of labeled corpus is of great importance for emotion classification tasks. Because manual labeling is too timeconsuming, hashtags have been used as naturally annotated labels to obtain large amount of labeled training data from microblog. However, the inconsistency and noise in annotation can adversely affect the data quality and thus the performance when used to train a classifier. In this paper, we propose a classification framework which allows naturally annotated data to be used as additional training data and employs a k-NN graph based data cleaning method to remove noise after noisy data has certain accumulations. Evaluation on NLP&CC2013 Chinese Weibo emotion classification dataset shows that our approach achieves 15.8% better performance than directly using the noisy data without noise filtering. After adding the filtered data with hashtags into an existing high-quality training data, the performance increases 3.7% compared to using the high-quality training data alone.
Sodium- potassium-activated adenosine triphosphatase and osmotic regulation by fishes.

JAMPQL, LEE M. , AND FRANKLIN H. EPSTEIN. Sodiumpotassiumactivated adenosine triphosphatase and osmotic regulation by fishes. Am. J. Physiol. 218(2) : 607-611. 1970. -The specific activity of sodiumpotassium-activated adenosine triphosphatase is high in the gills of sa1twater teleosts, and low in the gills of elasmobranchs and freshwater teleosts. The activity of NaK-ATPase in gill filaments and intestinal mucosa doubled when freshwater eels (AnguiZlu rostrata) were adapted to seawater for 2-3 weeks. A paradoxical finding was the high specific activity of NaK-ATPase in theaglomerular kidney of Luphius americanzls, reminiscent of the ATPase content of certain secretory organs, NaK-ATPase in rectal gland of Squalus acanthim was extremely high. The data indicate that NaK-ATPase activity varies with sodium transport in several organs of teleost and elasmobranch under differing circumstances of osmotic stress. The enzyme is likely, therefore, to play an important role in the active transport of sodium across epithe1ia1 membranes and the adjustment of marine animals to their environment.
Surgical-Site Infections (SSI) and the NNIS Basic SSI Risk Index, Part II: Room for Improvement

Surveillance of surgical-site infections (SSIs) with feedback of appropriate data to surgeons has been shown to be an important component of strategies to reduce SSI risk.2-4 For SSIs, the traditional wound classification system, which stratifies each wound into one of four categories (clean, clean-contaminated, contaminated, and dirtyinfected), has been available since 1964.3 Limitations of this system of risk stratification are well recognized. A simple index was developed during the Study on the Efficacy of Nosocomial Infection Control (SENIC) Project.5 Since 1991 a modification of this risk index has been used by National Nosocomial Infections Surveillance (NNIS) System hospitals.6 The NNIS Basic SSI Risk Index is a significantly better predictor of SSI risk than is the traditional wound classification system and performs well across a broad range of operative procedures. The NNIS Basic SSI Risk Index performed reasonably well for all but a handful of procedures7. [However,] the last decade has witnessed changes to healthcare delivery with regard to surgical procedures. Considerable numbers of procedures are now performed on outpatients, and the surgical patients admitted to hospitals tend to have higher intrinsic risk and are often discharged earlier.8-10
The Fanconi anemia pathway is downregulated upon macrophage differentiation through two distinct mechanisms

The Fanconi anemia (FA) pathway is a DNA-damage inducible pathway critical for genomic stability. FA patients typically display high cancer susceptibility and hypersensitivity to DNA-damaging agents such as cross-linkers and ionizing radiation. A key step in the activation of the FA pathway is monoubiquitination of the FancD2 protein. Here we report that the FA pathway is downregulated by two distinct mechanisms upon differentiation of THP-1 and HL-60 leukemia cells into macrophages. First, qRT-PCR analysis revealed a transcriptional downregulation of most components of the FA complex, including FancD2. Second, DNA damage-induced monoubiquitination of the remaining FancD2 became deficient at various stages of differentiation depending on the type of damage. This was attributed to the differentiation-induced downregulation of Chk1, which phosphorylates FancD2 as a prelude to its ubiquitination. Although protein gel blotting revealed that levels of FancD2 were greatly reduced in terminally differentiated macrophages and that FancD2 ubiquitination was abolished, double-strand breaks were proficiently repaired, likely through an increase in non-homologous end joining (NHEJ). It has been suggested that the FA pathway promotes repair of double-strand breaks via homologous recombination rather than NHEJ. Its downregulation in macrophages may thus be required to avoid promoting a repair mechanism that is inefficient in post-mitotic cells.
Big Data Techniques in Auditing Research and Practice: Current Trends and Future Opportunities

Abstract This paper analyses the use of big data techniques in auditing, and finds that the practice is not as widespread as it is in other related fields. We first introduce contemporary big data techniques to promote understanding of their potential application. Next, we review existing research on big data in accounting and finance. In addition to auditing, our analysis shows that existing research extends across three other genealogies: financial distress modelling, financial fraud modelling, and stock market prediction and quantitative modelling. Auditing is lagging behind the other research streams in the use of valuable big data techniques. A possible explanation is that auditors are reluctant to use techniques that are far ahead of those adopted by their clients, but we refute this argument. We call for more research and a greater alignment to practice. We also outline future opportunities for auditing in the context of real-time information and in collaborative platforms and peer-to-peer marketplaces.
Stabilization of networked control systems with packet loss and channel uncertainty

This paper considers the stabilization problem of networked control systems concerned both bounded channel uncertainty and arbitrary packet loss. Based on a previous approach which considers packet loss only, this paper proposes a new model to describe the NCS with both packet loss and channel uncertainty in an unified framework. The stability conditions of networked control systems are given by a common quadratic Lyapunov function approach. We give an approach to design the dynamic feedback controller via solving linear matrix inequalities (LMIs). Finally, a numerical example with simulations is given to show the effectiveness of the approach.
Relative validity of a food frequency questionnaire among tin miners in China: 1992/93 and 1995/96 diet validation studies

Abstract Objective Diet validation research was conducted to compare the respondents' reporting of dietary intake in a food frequency questionnaire (FFQ) with intake reported in food recalls. Because the population received annual salary increments that could modify food intake, diet validation studies (DVSs) were conducted during two time intervals. Design A 99-item FFQ was administered by an interviewer twice in a 1-year interval, and responses to each FFQ item were compared with 28 days of interviewer-administered food recalls that were collected in four 1-week intervals during each season of 1992/93. The second validation study in 1995/96 had a similar design to the earlier one. Setting A prospective cohort study of lung cancer among tin miners in China was initiated in 1992, with dietary and other risk factors updated annually. Subjects Among a cohort of high risk tin miners for lung cancer, two different samples (n = 141 in 1992/93, and n = 113 in 1995/96) for each diet validation study were randomly selected from four mine units, that were representative of all worker units. Results Miners reported a significantly higher average frequency of intake of foods in the food recalls than the FFQ, with few exceptions. Deattenuated Pearson correlation coefficients of the frequency of food intake between the FFQ and food recalls were in the range of –0.40 to 0.72 in both studies, with higher positive correlations for beverages and cereal staples than for animal protein sources, vegetables, fruits and legumes. The percentage of individuals with exact agreement in the extreme quartiles of intake in the food recalls and FFQ ranged from 0 to 100% in both studies. Conclusions Among Chinese miners, the range in correlations between the food recalls and the FFQ were due to: (i) market availability of foods during the food recall weeks compared to their annual reported intake in the FFQ; (ii) cultural perception of time; and (iii) differences in how the intake of mixed dishes and their multi-ingredient foods were reported in the recalls vs. the FFQ. The range in the percentage of agreement in the same quartiles and the changes in food intake over time may have implications for the analysis of the diet-disease relationship in this cohort.
Assessment of fine needle aspiration cytology and histopathology for diagnosing male breast masses.

OBJECTIVE To investigate the diagnostic accuracy of fine needle aspiration cytology (FNAC) from breast lesions in males and to determine the frequency of benign versus malignant histopathologic diagnoses in surgical biopsies from male breast lesions. STUDY DESIGN FNAC specimens from breast lesions taken from 241 males over 8.5 years were divided into four subgroups according to the original cytologic diagnoses. Diagnostic accuracy was verified with the Norwegian Cancer Registry. Ten years' worth of material from 809 surgical biopsies from male breast lesions was subgrouped according to the original histopathologic diagnoses. RESULTS Of the 809 surgical biopsies, 779 (96.3%) were benign lesions. Of the 241 fine needle aspirates, 27 (11.2%) were unsatisfactory for cytologic diagnosis. Of the remaining 214 cases, 200 benign cytologic diagnoses were confirmed at follow-up. Thus, there were no false negative cytologic diagnoses; eight malignant diagnoses were confirmed by later histopathologic examination of the surgical biopsy. CONCLUSION To reduce the high rate of surgical biopsies of benign male breast masses, we conclude that FNAC should be performed as a standard procedure in the clinical evaluation of male breast lesions.
Differential Effects of &agr;2-adrenoceptors in the Modulation of the Thermoregulatory Response in Mice Induced by Meperidine

Background:Meperidine proved to be more effective in treatment of shivering than equianalgesic doses of other opioids, especially pure &mgr;-agonists. Further, meperidine has well known nonopioid actions including agonistic effects at &agr;2-adrenoceptors in vitro. Accordingly, the authors investigated nonopioid receptor–mediated effects of meperidine on thermoregulation using a mice model of nonshivering thermogenesis. To differentiate conceivable &agr;2-adrenoceptor subtype specific interactions the authors analyzed wild-type mice and knock-out mice with deletion of the &agr;2A-, &agr;2B-, or &agr;2C-adrenoceptor. Methods:Ten mice per group (n = 60) were injected with saline, meperidine (20 mg/kg), saline plus naloxone (125 &mgr;g/kg), meperidine plus naloxone, fentanyl (50 &mgr;g/kg) plus naloxone, or meperidine plus atipamezole (2 mg/kg) intraperitoneally. Each mouse was subjected to the six different treatments. Then they were positioned into a plexiglas chamber where rectal temperature and mixed expired carbon dioxide were measured while whole body cooling was performed. Maximum response intensity and thermoregulatory threshold temperature of nonshivering thermogenesis were analyzed. Results:Meperidine decreased the thermoregulatory threshold temperature in wild-type mice and &agr;2B- and &agr;2C-adrenoceptor knock-out mice. This effect ended after injection of the &agr;2-adrenoceptor antagonist atipamezole. In wild-type and &agr;2B-adrenoceptor knock-out mice, the decrease of thermoregulatory threshold was not reversible by administration of the opioid receptor antagonist naloxone. In contrast, in &agr;2A-adrenoceptor knock-out mice, no decline of thermoregulatory threshold following meperidine injection was detectable. Maximum response intensity of nonshivering thermogenesis was comparable in all groups. Conclusions:The authors’ results suggest a major role of &agr;2-adrenoceptors, especially the &agr;2A subtype, in the mediation of thermoregulatory effects caused by meperidine in mice.
Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion and viral infection in lymphocytes

The human immunodeficiency virus 1 (HIV-1) envelope regulates the initial attachment of viral particles to target cells through its association with CD4 and either CXCR4 or CCR5. Although F-actin is required for CD4 and CXCR4 redistribution, little is known about the molecular mechanisms underlying this fundamental process in HIV infection. Using CD4+ CXCR4+ permissive human leukemic CEM T cells and primary lymphocytes, we have investigated whether HIV-1 Env might promote viral entry and infection by activating ERM (ezrin-radixin-moesin) proteins to regulate F-actin reorganization and CD4/CXCR4 co-clustering. The interaction of the X4-tropic protein HIV-1 gp120 with CD4 augments ezrin and moesin phosphorylation in human permissive T cells, thereby regulating ezrin-moesin activation. Moreover, the association and clustering of CD4-CXCR4 induced by HIV-1 gp120 requires moesin-mediated anchoring of actin in the plasma membrane. Suppression of moesin expression with dominant-negative N-moesin or specific moesin silencing impedes reorganization of F-actin and HIV-1 entry and infection mediated by the HIV-1 envelope protein complex. Therefore, we propose that activated moesin promotes F-actin redistribution and CD4-CXCR4 clustering and is also required for efficient X4-tropic HIV-1 infection in permissive lymphocytes.
Investigating Cross-Device Interaction between a Handheld Device and a Large Display

There is a growing interest in HCI research to explore cross-device interaction, giving rise to an interest in different approaches facilitating interaction between handheld devices and large displays. Contributing to this, we have investigated the use of four existing approaches combining touch and mid-air gestures, pinching, swiping, swinging and flicking. We look specifically at their relative efficiency, effectiveness and accuracy in bi-directional interaction between a smartphone and large display in a point-click context. We report findings from two user studies, which show that swiping is both most effective, fastest and most accurate, closely followed by swinging. What these two approaches have in common is the ability to keep the pointer steady on the large display, unaffected by concurrent gestures or body movements used to complete the interaction, suggesting that this is an important factor for designing effective cross-device interaction with large displays.
Relapsed Classic E-Cadherin (CDH1)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of HER2 (ERBB2) Gene Mutations

Purpose: We queried whether comprehensive genomic profiling using a next-generation sequencing–based assay could identify novel and unanticipated targets of therapy for patients with relapsed invasive lobular carcinoma (ILC). Experimental Design: DNA sequencing (Illumina HiSeq 2000) was conducted for 3,320 exons of 182 cancer-related genes and 37 introns of 14 genes frequently rearranged in cancer on indexed, adaptor-ligated, hybridization-captured libraries using DNA isolated from formalin-fixed paraffin-embedded sections from 22 histologically verified ILC. Results: A total of 75 genomic alterations were identified with an average of 3.4 alterations per tumor (range, 1–6), of which 35 were actionable for an average of 1.59 actionable alterations per patient (range, 0–3). Nineteen of 22 (86%) of the ILC samples harbored at least one actionable alteration. Six (27%) cases featured alterations in ERRB2 including 4 (18%) with ERBB2 mutation, 1 (5%) with an ERBB2 gene fusion, and 1 (5%) with an ERBB2 copy number gain (amplification). The enrichment of ERBB2 mutations/fusion in CDH1-mutated ILC (5 of 22, 23%) compared with the 5 ERBB2 mutations in a series of 286 non-CDH1-mutated breast cancers from which the ILC cases were obtained (5 of 286, 2%) was significant (P = 0.0006). Conclusions: Comprehensive genomic profiling of relapsed CDH1-mutated ILC revealed actionable genomic alterations in 86% of cases, featured a high incidence of ERBB2 alterations, and can reveal actionable alterations that can inform treatment decisions for patients with ILC. Clin Cancer Res; 19(10); 2668–76. ©2013 AACR.
Do relative prices of nontraded goods explain relative movements in price indices across U . S . cities ? * August 2006

Inclusion of nontraded goods prices has been shown to be partly responsible for slow convergence in price indices across major cities in the United States (Cecchetti et al 2002). Drawing upon insights provided by well known theories, this paper uses panel econometric methods to seek evidence in U.S. city level Consumer Price Index (CPI) data of a systematic long-run relationship between prices of nontraded goods relative to traded goods, and overall relative price. While the results for convergence of overall relative prices are mixed, the hypothesis of a long-run relationship between overall relative prices and relative prices of nontraded goods is overwhelmingly rejected. However, the evidence of cointegration between relative prices of nontraded goods across cities suggests that relative movements of overall prices could be driven by temporary shocks that move nontraded goods prices away from their long-run paths.
Data at the moment of infinite expansion for polarized Gowdy

In a recent paper by Thomas Jurke, it was proved that the asymptotic behaviour of a solution to the polarized Gowdy equation in the expanding direction is of the form αln t + β + t−1/2ν + O(t−3/2), where α and β are constants and ν is a solution to the standard wave equation with zero mean value. Furthermore, it was proved that α, β and ν uniquely determine the solution. Here we wish to point out that given α, β and ν with the above properties, one can construct a solution to the polarized Gowdy equation with the above asymptotics. In other words, we show that α, β and ν constitute data at the moment of infinite expansion. We then use this fact to make the observation that there are polarized Gowdy spacetimes such that in the areal time coordinate, the quotient of the maximum and the minimum of the mean curvature on a constant time hypersurface is unbounded as time tends to infinity.
LOW RISK FITS TO DISCRETE INCOMPLETE MULTI-WAY LAYOUTS

The discrete multi-way layout is a widespread data-type asso- ciated with regression, experimental designs, gene or protein chips, digital images or videos, and more. A discrete multi-way layout has a finite number of factor level combinations. The layout may be unbalanced or incomplete or both. We consider candidate fits to an incomplete layout that are least squares fits to certain submodels induced by tensor product space ANOVA models for a complete layout. The candidate estimator with smallest esti- mated risk is selected. Multiparametric asymptotics under a general (sat- urated) Gaussian model show that the selected estimator achieves smallest asymptotic risk over the candidate class through bias-variance trade-off.
Wigner formula of rotation matrices and quantum walks

Quantization of a random-walk model is performed by giving a qudit (a multicomponent wave function) to a walker at site and by introducing a quantum coin, which is a matrix representation of a unitary transformation. In quantum walks, the qudit of the walker is mixed according to the quantum coin at each time step, when the walker hops to other sites. As special cases of the quantum walks driven by high-dimensional quantum coins generally studied by Brun, Carteret, and Ambainis, we study the models obtained by choosing rotation as the unitary transformation, whose matrix representations determine quantum coins. We show that Wigner's (2j+1)-dimensional unitary representations of rotations with half-integers j's are useful to analyze the probability laws of quantum walks. For any value of half-integer j, convergence of all moments of walker's pseudovelocity in the long-time limit is proved. It is generally shown for the present models that, if (2j+1) is even, the probability measure of limit distribution is given by a superposition of (2j+1)/2 terms of scaled Konno's density functions, and if (2j+1) is odd, it is a superposition of j terms of scaled Konno's density functions and a Dirac's delta function at the origin. For the two-, three-,more » and four-component models, the probability densities of limit distributions are explicitly calculated and their dependence on the parameters of quantum coins and on the initial qudit of walker is completely determined. Comparison with computer simulation results is also shown. « less
Moderacje relacji innowacyjność organizacji - wyniki

Streszczenie: Celem opracowania jest rozpoznanie charakteru związków zachodzących między innowacyjnością przedsiębiorstwa a jego wynikami. Ustalenia badawcze odnoszące się do relacji innowacyjność organizacji – wyniki, są niejednoznaczne. Wskazują na pozytywny wpływ innowacyjności na wyniki organizacji. Studia literatury ujawniły istnienie czynników pośredniczących tej relacji. W opracowaniu odsłonięto niektóre zmienne moderujące tę relację. Identyfikacja zmiennych ma istotne znaczenie, pozwala bowiem na określenie warunków, w których omawiana zależność występuje i odróżnienie ich od warunków, w których zanika.
Overview of Personal Privacy Protection Technology in Big Data

Big Data called new oil in the future is affecting people's life. It has attracted much attention from academy, industry and national government departments. But there are many security problems in the collection, storage, mining and displaying of Big Data and privacy protection in it is directly related to the interests of user. Firstly, this paper will introduce concept of Big Data and analyzes many information security problems in it. Then, it will discuss the key privacy protection technologies and recent advances in anonymous protection, data encryption, access control, cloud storage location privacy and legal regulations. Finally, this paper will summarize and discuss further study of Big Data privacy protection.
Barriers to cooperation in business networks. The case of the wielkopolska region

Knowledge has become one of the most important factors for the competitiveness of the globalized economy and the engine of rapid economic and social growth. Europe spends 0.8% of GDP less than the US and 1.5% less than Japan on R&D. The large European market is still not innovation-friendly enough. In reply the Innovation Union has become one of the seven flagship initiatives of the Europe 2020 strategy[European Commission, 2010].