Miracle-dz/UniFAR-FTUs huggingface dataset:
The development of the neural crest-derived intrinsic innervation of the lung

The autonomic airway ganglia that comprise the intrinsic lung innervation are derived from vagal neural crest cells (NCC) that migrate tangentially from the foregut into the embryonic lung buds. The aim of this PhD thesis was to investigate the mechanisms that direct NCC from the foregut into the lungs and that subsequently influence their development. A novel combination of cell labelling, using Wnt1Cre:Rosa26YFP double transgenic reporter mice, and Optical Projection Tomography (OPT) imaging was employed to visualize lung innervation. Results showed that NCC migrated into the lungs from the esophagus early in development, accumulated around the epithelial tubules and differentiated into an extensive network of neurons and glial cells. Next, chick intraspecies grafting was used to test the developmental potential of lung and gut NCC. Results showed that when NCC from the gut were back-grafted into the early migration pathway these cells colonised both the lungs and gut, indicating that vagal NCC are not prespecified to colonise either organ and are thus likely to respond to common signalling cues. When potential cues were tested in organotypic lung culture, NCC migrated towards sources of the RET (Rearranged during Transfection) ligand GDNF (Glial-cell-line-derived neurotrophic factor), suggesting that the RET signalling pathway is involved in NCC colonisation of the lung. However, examination of RET mutants indicated that this pathway is not necessary for NCC colonisation of the lung, since lung innervation in Ret-/- mouse embryos was similar to controls. Lung innervation was further examined in several mouse mutants with known NCC defects. Intrinsic ganglia formation was altered in Sox10Dom and Tbx1 mutant mouse lungs, implicating a role for vagal nerve projections in guiding NCC within the lung. Together these studies have described the development of intrinsic lung innervation in the avian and mammal and examined multiple mechanisms underlying NCC development within the lung.
As possibilidades da utilização de técnicas de autorregulação da aprendizagem por alunos de graduação

In this work, the use of self-regulation of learning stands out as a way to provide the student with active participation, autonomy and responsibility for their learning process. In order to investigate the relationship between the use of self-regulation of learning and the academic performance of university students. The theme was designed based on the guiding question “To what extent can the self-regulatory learning technique help in the academic performance of undergraduate students? ” The methodology consists of an integrative review of works published between 2009 and 2019 in the Scielo and ScienceDirect databases. The following expressions were used as descriptors: Self-regulation of learning, Self-regulation of learning, Learning strategies (Learning strategies, Strategies of learning) and Undergraduate education (Theaching of graduation, Enseñanza de graduación). The criteria for selecting the articles were to be published in Portuguese, English or Spanish, to have been published since 2009 and to be indexed in one of the databases mentioned above. 37 articles were found and 17 articles that dealt exclusively with the topic were selected. The others were excluded because they did not comply with the criteria mentioned above. All works showed the effectiveness of self-regulation to improve academic performance, some focused on the best strategies to achieve this goal, highlighting the need to work on motivational aspects, and socioenvironmental influences. It can be concluded that the self-regulation of learning has a direct relationship with the improvement in the effectiveness of learning and academic performance, but there are still some challenges to be overcome for the popularization of its applicability.
Mycotoxin Management in Agriculture: a Review

This review was done to highlight of the worldwide contamination of foods and feeds with mycotoxins as a significant problem. Mycotoxins are secondary metabolites of moulds that have adverse effects on humans, animals, and crops that result in illnesses and and direct economic losses in crop yield and stored agricultural products. Aflatoxins, ochratoxins, trichothecenes, zearelenone, fumonisins, tremorgenic toxins, and ergot alkaloids are the mycotoxins of greatest agro-economic importance. Some moulds are capable of producing more than one mycotoxin and some mycotoxins are produced by more than one fungal species. Often more than one mycotoxin is found on a contaminated substrate. Factors influencing the presence of mycotoxins in foods or feeds include environmental conditions related to storage that can be controlled. Other extrinsic factors such as climate or intrinsic factors such as fungal strain specificity, strain variation, and instability of toxigenic properties are more difficult to control. The challenges in mycotoxin management are enormous due to the frequency, the complexity and variability in occurrence with several aspects make the management and control of mycotoxins difficult. Monitoring or surveillance of mycotoxin levels in crops and products is an important management tactic and it can be implemented at both pre-harvest and post-harvest stages.
An online state of health estimation method based on battery management system monitoring data

A state of health (SOH) estimation method that can be achieved online and only requires battery management system (BMS) detection data is proposed in this article. In the State of Health mathematical model proposed in this article, the using time of power battery is treated as an independent variable and SOH is treated as a hidden variable. And the mathematical model just used online process data from BMS. So it would make the SOH estimation method more suitable for actual engineering. Then, the article proposes an interleaved time model parameter update framework to reduce the computational complexity of the algorithm in a single sampling period. In this framework, we propose a fast model parameter identification algorithm that uses nonlinear least squares to initialize a genetic algorithm searched range. Finally, the whole method is verified by using the NASA database. The results prove that the proposed online SOH estimation method has higher SOH estimation accuracy and is more suitable for engineering applications in the field of electric vehicles than the existing SOH estimation methods.
Calycosin may improve outcomes of ischemic stroke in rats by inhibiting activated microglia in brain

Calycosin, an isoflavonoid, is the major active component in Radix Astragali. It has a neuroprotective effect against cerebral ischemia/reperfusion in rats. The mechanisms remain unclear. This study aimed to assess whether calycosin improves outcomes of ischemic stroke by affecting activated microglia formation. After 1 h of reperfusion following ischemia for 60 minutes induced by middle cerebral artery occlusion (MCAO), Sprague‐Dawley rats were intragastrically administered a dose of 30 mg/kg. Then, an i.g. dose of 30 mg/kg of calycosin was administered daily for consecutive 7 days. Neurological deficit, infarct volume, histopatholical and immunofluorescence staining were evaluated after 7 days of reperfusion. Treatment with calycosin significantly ameliorated neurological deficit and infarct volume after cerebral ischemia reperfusion. Calycosin also attenuated MCAO‐induced activated microglia (evidenced by the increased numbers of both the amoeboid microglia and the cells colocalized with microglia and tumor necrosis factor‐alpha‐specific markers). Our results suggest that calycoin may improve outcomes of ischemic stroke in rats by inhibiting activated microglia in brain.
Three Experimental Phases of Cornstarch-Based Biodegradable Plastic

Three Experimental Phases of Cornstarch-Based Biodegradable Plastic is the focus of this current study whose purpose was to create a bio-plastic from eco-friendly materials as a platform for an alternative commercial plastic. This study used a pre-experimental research design where three bio-plastic experiments were monitored to identify which among them was likely to produce the most efficient bio-plastic. At the end of the study, it was concluded that in terms of elasticity, tear resistance, appearance, texture, and odor, Experimental Two with four tablespoons of cornstarch, one cup of water, two tablespoons of vinegar, and two tablespoons of glycerin, is the most reliable among the three experiments. Hence, this study recommends to the biologists and scientists that may use this study to help them find ways to lessen biological problems caused by non-biodegradable plastics; to the producers that the study may help them to create and manufacture bio-plastics and to improve the study using other materials for the product to last longer indoors; to the consumers that the study may let them know the reliability and liability of the plastic they use in their everyday life; and to the future researchers who will want to conduct a further study about bio-plastics, this study may serve as a related study and think of an intervention to improve the results from the problem.
Vertebrate Limb and Somite Morphogenesis

The rapid growth of interest in limb and somite development in recent years is reflected in the contents of this book, which provides a full account of the current state of research in the field. It is in the vertebrate systems that most is known about the relationship between activities at the cellular level and events at the morphogenetic level, which provides the complex system of limb development. These two levels are covered in this book, which includes chapters on a variety of aspects of development, from studies of ultrastructure to computer simulation models of limb and somite development. British Society for Developmental Biology Symposium 3 £20.00 net
Enraizamiento de estacas de especies forestales

Se explican detalladamente los procedimientos para obtener el enraizamiento adecuado de estacas de especies forestales en invernadero. Se dan las recomendaciones sobre el tipo de invernadero, el riego, el sustrato, los recipientes de produccion, la preparacion y siembra de las estacas, el manejo sanitario y la programacion de la produccion. Se brindan especificaciones para Eucalyptus spp, Cupressus lusitanica, Alnus acuminata, Tectona grandis, Hieronyma alchorneoides, Ulmus mexicana, Gmelina arborea, Vochysia guatemalensis y Terminalia amazonia.
The relationship between nepotism and disengagement: the case of institutions in Ethiopia

Purpose- This article examines the relationship between nepotism and employee disengagement across Ethiopian organizations. In organizations where nepotism is widely experienced, employee recruitment and promotion cannot be performed fairly. Therefore, individual and organizational competence would be under question which in turn may result in an unfair work environment. Consequently, employees may be alienated from work. The purpose of this study was hence to examine the relationship between the constructs of nepotism and disengagement in the organizations of Ethiopia as a developing country. Methodology- A total of 255 employees were (M=202 and F=53) conveniently selected and made to fill the questionnaire in a face to face and on-line fashion. Nepotism and Disengagement scales were used to measure the variables. All of the variables were measured by scales with six-point intervals. Findings - The factor analyses revealed that nepotism has two factors: nepotistic relationships and preferential policy. Disengagement turned out to be a uni-directional construct. The regression analysis revealed that nepotistic relationships significantly and positively contributed to disengagement whereas preferential policy did not significantly contribute to disengagement. Conclusion– Since the participants perceived nepotistic relationships at work, the resulting employee disengagement is a potential threat for the future of organizations in terms of interpersonal relationships and performance. For preventing possible multi-faceted organizational problems that can affect the efficiency of business activities, managerial intervention seems to be required.
Research on the Image Annotation Technology for Product Quality and Safety Inspection Data

In recent years, the vicious events about quality and safety in China have continued to bring serious impacts on people’s lives and property. The effective analysis and processing of product quality and safety inspection data will provide intellectual support for the overall improvement in product quality, and the effective control of prominent quality and safety problems in China. Aiming at the phenomenon that there is a large amount of image information in the quality detection data, this paper proposed an image annotation technology based on big data fusion, conducted weight fusion to image similarity and image user similarity, calculated the total similarity of images, and made denoising treatment. The experimental results showed that the method proposed in this study could annotate the quality test data well.
Gender differences in the perception of safety in public transport

Concerns over women's safety on public transport systems are commonly reported in the media. We develop statistical models to test for gender differences in the perception of safety and satisfaction on urban metros and buses by using large‐scale unique customer satisfaction data for 28 world cities over the period 2009–2018. Results indicate a significant gender gap in the perception of safety, with women being 10% more likely than men to feel unsafe in metros (6% for buses). This gender gap is larger for safety than for overall satisfaction (3% in metros and 2.5% in buses), which is consistent with safety being one dimension of overall satisfaction. Results are stable across specifications and robust to inclusion of city level and time controls. We find heterogeneous responses by sociodemographic characteristics. Data indicate that 45% of women feel secure in trains and metro stations (and 55% in buses). Thus the gender gap encompasses more differences in transport perception between men and women rather than an intrinsic network fear. Additional models test for the influence of metro characteristics on perceived safety levels and find that more acts of violence, larger carriages and emptier vehicles decrease women's feeling of safety.
Calculation of Value of Lost Load With a New Approach Based on Time and Its Effect on Energy Planning in Power Systems

Stable developments in the competition and liberalization of the electricity market have necessitated the need for up-to-date policies in electricity planning and made it necessary to consider some economic costs in addition to generation costs in power plants. Among these economic costs, the socio-economic parameters are taken into consideration and the lost power value is defined as the cost of lost electricity or the lost load value defined as the cost and the value obtained as a result of multiplying the expected energy. The value of lost load is a useful value for planning about the cost of the total capacity of the power supplies. Regarding payments and suppliers made by customers, the marginal price of the system cannot be clearly stated, and it is very difficult to obtain the lost value, which is very important for developed and developing countries. In general, it refers to the monetary value of losses in electricity supply as a result of interruptions in all segments of electrical energy systems. As a result, the lost load value can be considered as a useful variable to measure one of the dimensions of energy supply security in the energy sector in a country, temporarily. In this study, the seasonal lost load value for the power system is obtained by using an innovative method for the national power system. In addition, it is argued that these values change periodically as well as consumer-based, not as a single parameter for countries.
Fried Shallot Quality: Perception and Differentiation

Sensory attributes and consumers’ perception of commercial fried shallots related to their quality were investigated. Consumers’ perception data were collected by online survey, followed by the randomly selected respondents. The survey results were then confirmed using the descriptive sensory method and hedonic test on five commercial fried shallots. Consumers’ perception of the high quality fried shallot was concluded as follows: the flour uncoated fried shallots, golden brown color, and whole slices-shaped fried shallots which were chosen by 80.4; 84.0; and 64.2% respondents, respectively. The desirable sensory attributes were indicated by crispness, savory taste and fragrant sulfury aroma were confirmed by 91.3; 78.1 and 73.9% of respondents, respectively. Meanwhile, the undesirable attributes of fried shallots included rancid aroma and bitter taste were 95 and 75% of respondents. The sensory characteristics of commercial products confirmed the survey results related to product perception. Differentiation of the five products based on descriptive and hedonic tests was also reported in this study. Description of fried shallot characteristics by consumers and the confirmation of commercial fried shallots with highest desirable characteristics can be used by the food producers to increase product quality. Current Research in Nutrition and Food Science www.foodandnutritionjournal. org ISSN: 2347-467X, Vol. 08, No. (1) 2020, Pg. 97-106 CONTACT C. Hanny Wijaya channywijaya@apps.ipb. ac.id Department of Food Science and Technology, Faculty of Agricultural Engineering and Technology, Bogor Agricultural University, IPB Campus Darmaga, 16680, Bogor, Indonesia. © 2020 The Author(s). Published by Enviro Research Publishers. This is an Open Access article licensed under a Creative Commons license: Attribution 4.0 International (CC-BY). Doi: http://dx.doi. org/10.12944/CRNFSJ.8. 1.09 Article History Received: 24 October 2019 Accepted: 22 March 2020
Validez de las técnicas para evaluar la foria de cerca

espanolAntecedentes: si bien varios estudios han investigado la repetibilidad de tecnicas para medir las heteroforias, ha habido pocas pruebas de su validez. El presente estudio examino la capacidad de tres tecnicas: Von Graefe (VG), baston de Maddox Rod (MR) y Thorington modificado (MT), para cuantificar un cambio conocido en la heteroforia. Metodos: se estudiaron 30 sujetos jovenes utilizando los 3 procedimientos. Se cuantifico la heteroforia cercana (40 cm) sin un prisma de base afuera adicional y con este. Hubo cinco valores posibles disponibles: 2, 4, 6, 8 y 9Δ. Despues de 24h, la medicion se repitio utilizando la misma tecnica, con uno de estos prismas agregados a la correccion refractiva. El cambio medido en la desviacion se comparo con la diferencia esperada, es decir, la magnitud del prisma. Resultados: el valor medio de heteroforia antes de la introduccion de un prisma usando VG fue significativamente mas exoforico que los resultados obtenidos usando las otras 2 tecnicas (p = 0,035). No se observaron diferencias significativas entre el cambio medido y el predicho en la heteroforia despues de la introduccion del prisma para VG y MT, pero se encontro una diferencia significativa con MR (p EnglishBackground: While a number of previous studies have investigated the repeatability of techniques designed to measure heterophoria, there have been few studies of their validity. Accordingly, the present study examined the ability of 3 standard techniques; Von Graefe (VG), Maddox Rod (MR) and Modified Thorington (MT) tests to quantify a known change in heterophoria. Methods:The study was performed on 30 young subjects using each of the 3 procedures listed above. Near (40 cm) heterophoria was quantified both without and with an additional base-out prism. Five possible values were available, namely 2, 4, 6, 8 and 9Δ. After a period of 24 hours, the heterophoria measurement was repeated using the same technique with one of these prisms added to the refractive correction. Results:The mean heterophoria value measured before the introduction of prism using the VG procedure was significantly more exophoric than the findings obtained using the other 2 techniques (p = 0.035). No significant difference was observed between the measured and predicted change in heterophoria following the introduction of the prism for the VG and MT procedures, but a significant difference was found with the MR technique (p
Local Key Estimation In Classical Music Recordings: A Cross-Version Study on Schubert’s Winterreise

While global key and chord estimation for both popular and classical music recordings have received a lot of attention, little research has been devoted to estimating the local key for classical music. In this work, we approach local key estimation on a unique cross-version dataset comprising nine performances (versions) of Schubert’s song cycle Winterreise—a challenging scenario of high musical ambiguity and subjectivity. We compare an HMM-based system with a CNN-based approach. For both models, we employ a similar training procedure including the optimization of hyperparameters on a validation split. We systematically evaluate the model predictions and provide musical explanations for key confusions. As our main contribution, we explore how different training–test splits affect the models’ efficacy. Splitting along the song axis, we find that both methods perform similarly well. Splitting along the version axis leads to clearly higher results, especially for the CNN, which seems to effectively learn the harmonic progressions of the songs ("cover song effect") and successfully generalizes to unseen versions.
Fistule carotido-caverneuse: à propos d’un cas

Les auteurs apportent l’attitude diagnostique de notre service dans la prise en charge d’une fistule carotido-caverneuse, apparue un an apres un accident de la voie publique avec traumatisme crâni-facial chez un jeune de 21 ans. Un scanner cerebral et une IRM encephalique ont ete realise affin de rattache une exophtalmie pulsatile unilaterale a une Fistule Carotido- Caverneuse suspectee cliniquement.