Miracle-dz/UniFAR-FTUs huggingface dataset:
Velike baze podataka - Big Data, primena u vojno-bezbednosnom sistemu

ktuelni bezbednosni izazovi razvijenih zemalja su kontrola granica; ilegalni protok ljudi, oružja i novca; sajber terorizam; islamski radikalizam. Upotreba i analiza velikih količina podataka – Big Data doprinosi preciznijem identifikovanju faktora relevantnih u procesu donošenja odluka u mnogim sferama. Efikasno praćenje kretanja pojedinaca, potpunije predviđanje postupaka subjekata, sprečavanju neželjenih aktivnosti useljenika u zemlji domaćina je takođe domen primene. Savremena vojna oprema podrazumeva manipulaciju voluminoznim podacima. Domen primene Big Data jeste osnovni istraživački cilj rada. Autori dodatno ukazuju na problem kompleksnosti akumulacije podataka; volumen evidencije kriminalno-terorističkih elemenata; efektivnost rada službi bezbednosti u oblasti sajber aktivnosti kao i efikasnost rada vojnih organa. Stručni rad elaborira signifikantnost Big Data u efikasnosti vojnih dejstava, praćenja inostranih visoko tehnoloških aktivnosti, primene u vojnim operacijama. Istraživački rad je zasnovan na kvalitativnoj metodi. Predmet analize je način korišćenja i primena velikih količina podataka u bezbednosnim strukturama industrijski razvijenih zemalja. Opis stepena i obima aplikacije voluminoznih podataka u odbrambenom sistemu zemlje je poseban doprinos rada. Nalazi upućuju na relevantnost velikih količina podataka u namenskoj industriji. Istovremeno, zaključci upućuju na značaj Big Data u podizanju nivoa nacionalne sigurnosti i međuinstitucionalnom procesuiranju podataka u sajber-prostoru i obaveštajnim aktivnostima. Rezultati sprovedene analize su od važnosti za vojno-bezbednosne strukture u zemlji kao i za državni administrativni aparat.
Benefit-risk assessment of interferon-b therapy for relapsing multiple sclerosis

IFN-β therapy has a central place in the management of relapsing multiple sclerosis, as demonstrated by the pivotal studies of three IFN-β treatment regimens. However, questions remain concerning the optimal choice of preparation and dose regimen. The benefit−risk ratio for a given preparation is an important consideration in optimising treatment for an individual patient. Of the three IFN-β preparations currently available, all have shown benefit on activity measures (relapses and active lesions apparent on magnetic resonance imaging), while benefit on progression measures (disability and total lesion burden) has been less consistent. Available data across studies suggest that dose and/or dose frequency are important determinants of efficacy, a finding supported by direct comparative data on different IFN-β preparations. The added benefit of high-dose, high-frequency IFN-β therapy is not achieved at the cost of compromised safety or tolerability, indicating that three-times-weekly treatment offers a superior benefit−risk ratio to once-weekly treatment. The potential advantages of IFN-β therapy may be enhanced by regular monitoring of efficacy and safety in order to maintain patients on therapy beyond the first few months when side effects are most apparent.
Generic error probabilities

This paper presents new forms for an error probability associated, with the phase angle between two vectors perturbed by Gaussian noise. An interesting consequence of the underlying generic form is a new expression for the symbol error rate in MDPSK that is very similar to its counterpart for MPSK. The generic error probability is further shown to contain as special cases MPSK, MDPSK, CPFSK, and digital FM; and to give a new expression for the Marcum Q-function. The generic error probability also simplifies the error probability expressions in other situations such as nonorthogonal signaling, maximum likelihood differential detection of DPSK with block-by-block detection, and Gray coding of MDPSK.
The study of eddy current in rotor and circuit coupling analysis for small size and ultra-high speed motor

Recent developments of power electronics technology, low-loss iron core materials and highly efficient permanent magnet, etc have made it possible to realize a small size, high or ultra-high speed, and high performance electrical drive system. We designed and built a trial ultra-high speed drive system of 2 poles, 5 kW, 240,000 rpm and had described our prototype system and showed some experimental results in the previous paper. This kind of motor is supported to development of various technology, such as control technology including DSP, FPGA, etc., power conversion technology and design technology which includes a finite element method. The development as a comprehensive drive system is necessary. In this paper we describe the coupled analysis model which is represented for entire drive system. This model was used to evaluate the fundamental motor characteristics at the first of design stage. And the model also has been applied to total systematic approach to enhance the total drive system. Trial for reducing the eddy current in the inconel material for magnetic-scattering-proof was also examined in consideration of transient analysis by using the FEM for this ultra-high speed motor
FLASH and NPAT positive but not Coilin positive Cajal bodies correlate with cell ploidy

Cajal Bodies are one of many specialised organelles contained in the eukaryotic cell nucleus, and are involved in a number of functions, including regulation of replication-dependent histone gene transcription. In normal diploid cells their number varies between 0 and 4 depending on the cell cycle phase, although in cancer cell lines their number is extremely variable and it has been suggested that it correlates with cell ploidy. Here we show that in mammals cells, as in Drosophila, two distinct though functionally related bodies exist: a histone gene locus body and a Cajal body. The first one can be detected using FLASH or NPAT as markers while the second is labelled using antibodies against Coilin.Only the number of FLASH/NPAT histone gene locus bodies correlates with ploidy and only these organelles appear to be regulated during the cell cycle. Finally, we show that the two organelles completely co-localize during the S phase of the cell cycle.
A Model to Determine and Improve an Organisation’s Configuration Management Capability

This master thesis has enhanced the field of configuration management by developing a model that can evaluate an organisations configuration management capability. It also verifies that the already existing theory in the field of configuration management is applicable in industries where the main goal is to preserve and develop the operational capability of its assets. Solvina AB is a consultancy firm mainly working with clients in this industry. As a part of their service range, they advise clients in how to optimise their configuration management implementations to increase long-term operational capability and reduce project costs. This has become important for their clients in today’s global market as companies are continuously forced to increase operational eectiveness and eciency as markets grow more competitive. However, Solvina experiences dif- ficulties as there exist no formal evaluation process to evaluate the configuration management capability and identify improvement areas in these industries. Based on this background, this master thesis has firstly identified ten factors that are important to operate an ecient and eective configuration management. Based on these factors, an evaluation model has been developed. The model is simply a structured collection of activities that an organisation’s configuration management implementation can be expected to include in order to be successful. It can identify an organisation’s current configuration management capability and improvement areas. The model’s design and structure is based on the ability to vary the depth of the analysis to make it a useful tool for all organisations in the industry, independent on size and available resources. As future work, it is recommended that the model is further verified both with the practitioners of it and multiple interviewees to increase the granularity and reach the full potential of the model. Additionally, the data collection method needs to be further developed due to the barrier between the configuration management terminology and the industry terminology.
Target Marketing of Small-Scale Festival Attendees: A Scoping Study

Targeting festival attendees based on key criterion can provide a greater return on investment for festival organizers. Despite considerable insight into festival attendee segmentation, studies have failed to validate targeted segments, which provides the impetus for this research note. This research segments and targets attendees to six small-scale festivals across three countries by applying Kotler's target marketing criteria (measurability, substantiality, accessibility, actionability). Results suggest that regardless of the country or event type, a targeted small-scale festival segment, labeled as satisfied, involved experience attendees, exists. Implications are outlined and opportunities for future research are considered.
Activity of the Mason-Pfizer Monkey Virus Fusion Protein Is Modulated by Single Amino Acids in the Cytoplasmic Tail

ABSTRACT Mason-Pfizer monkey virus (M-PMV) encodes a transmembrane glycoprotein with a 38-amino-acid-long cytoplasmic tail. After the release of the immature virus, a viral protease-mediated cleavage of the cytoplasmic tail (CT) results in the loss of 17 amino acids from the carboxy terminus and renders the envelope protein fusion competent. To investigate the role of individual amino acid residues in the CT in fusion, a series of mutations was introduced, and the effects of these mutations on glycoprotein biosynthesis and fusion were examined. Most of the alanine-scanning mutations in the CT had little effect on fusion activity. However, four amino acid substitutions (threonine 4, lysine 7, glutamine 9, and isoleucine 10) resulted in substantially increased fusogenicity, while six (leucine 2, phenylalanine 5, isoleucine 13, lysine 16, proline 17, and glycine 31) resulted in much-reduced fusion. Interestingly, the bulk of these mutations are located upstream of the CT cleavage site in a region that has the potential to form a coiled-coil in the Env trimer. Substitutions at glutamine 9 and isoleucine 10 with alanine had the most dramatic positive effect and resulted in the formation of large syncytia. Taken together, these data demonstrate that individual residues within the cytoplasmic domain of M-PMV Env can modulate, in both a positive and negative manner, biological functions that are associated with the extracellular domains of the glycoprotein complex.
Factors Affecting Internet Users: A Comparative Investigation between Romania and Turkey

The main research aims to highlight differences in the number of Internet users in Romania compared to Turkey in the period 1993- 2016. For a better understanding of the topics studied in the mirror was present evolution of the number of total population of the two countries. Data for the analysis were taken from the National Institute of Statistics recording in the two countries Hypothesis testing and data analysis was performed using ANOVA and descriptive statistics. The research results reveal that although in the period 1993-2016 averages on the population growth in the two countries were very different however averages for the number of Internet users remained equal. At the end of 2016, Turkey had a total population of 3.4 times higher; whereas Romania had 1.04 times more Internet users.
The effect of sintering profile and printed layer variations with inkjet-printed large-area applications

Inkjet-printed conductors with large areas and increased layer thickness may cause challenges with the materials applied. The possibly required increased sintering energy can result in exceeding the heat tolerance of the substrate and cracks in the conductor surface can be formed. The advantages of inkjet print technology can be applied to reduce these challenges by limiting the ink usage by varying the conductor thickness locally or even removing the parts of material from the layout. In this paper, large-area RF applications are studied in terms of varying conductive ink usage and sintering profile. An antenna type with high current density areas is used as a demonstrator of an application requiring larger uniform printed area. The paper shows the advantages of limited local printing on additional layers compared to printing full layers. Two different sintering profiles are applied to differently printed antenna versions fabricated for 868 MHz and 2.4 GHz frequencies. It is shown, that with less sintering energy, the antennas with only local additions perform better than antennas with fully printed antennas with more ink. With longer sintering process time, the local antenna and the fully printed antenna behave equally in terms of total efficiency.
On the Deployment of Citizens’ Privacy Preserving Collective Intelligent eBusiness Models in Smart Cities

During the last two decades the world is being transformed towards a virtual agglomerate of large interconnected cities. Moreover, an integration of digital infrastructures with the physical city infrastructure and facilities is taking place. This integration includes data generating sensors and various internet-connected devices which are dispersed in a city having as a target to offer a variety of services in order to ease citizens’ daily lives. In this, so called, smart city digital ecosystem, companies provide eBusiness models that are based on Collective Intelligence based decision making applications focusing on discovering citizens’ needs by collecting data related to their activities. However, the lack of privacy preserving mechanisms in such applications that eliminate the risk of correlation between citizens’ activities and their identities discourages citizens from providing their data to commerce systems. In this paper, we first discuss a new privacy preserving authentication technology, the Privacy-ABCs, and its successful deployment in a course evaluation pilot in higher education as well as a social networking application for pupils in a school environment. Based on the wide acceptance of this technology by the pilot users, we propose the deployment of a Privacy-ABCs based authentication system in a generic Collective Intelligent eBusiness model in a Smart City. The incorporation of this authentication technology in Collective Intelligence based eServices, has the potential of establishing new market opportunities since citizens’ anonymity will increase their incentives to provide valuable data related to their consuming activities and buying preferences as they move about in the city.
Visual Illusions Based on Processes: New Classification System Needed

Illusions have mainly been classified according to their phenomenological appearance. Here, I plead for a new classification approach based on processing areas or mechanisms. Classifying visual illusions according to processing areas or mechanisms may not only be valuable for a better understanding of the visual system but also for diagnostics of impairments, degenerative effects, and lesions (from retina to striate and extra-striate cortex).
Fukushima, quel impact sur les entreprises françaises cotées de la filière de production d'électricité d'origine nucléaire ?

Fukushima, what impact on the listed French companies of the sector of nuclear electricity production? This communication reports of ongoing research on the reaction of financial markets following a serious industrial accident, also known as environmental crisis. The studied event is the Fukushima nuclear accident which began on March 11th, 2011. The results of an event study conducted on a sample of 16 French companies operating in the nuclear power generation sector pointed out a negative and significant average market reaction. The abnormal returns can be explained by contextual variables such as the nature of the activity and the media exposure of companies. Finally, the analysis of press releases issued by these companies after the accident permitted to identify 5 types of reaction from them.
Custom Development as an Alternative for ERP Adoption by SMEs: An Interpretive Case Study

There have been few studies of the adoption of custom-developed enterprise resource planning (ERP) systems. An interpretive case study of a SME in the agri-food industry was thus conducted to analyze this phenomenon. The study shows that custom ERP seems to represent a credible alternative for ERP adoption by small and medium-sized enterprises (SMEs) and that to minimize risk at the adoption stage, a SME can proceed in a rather intuitive and unstructured manner, based however upon certain principles, policies, and practices.
WR1065 mitigates AZT‐ddI‐induced mutagenesis and inhibits viral replication

The success of nucleoside reverse transcriptase inhibitors (NRTIs) in treating HIV‐1 infection and reducing mother‐to‐child transmission of the virus during pregnancy is accompanied by evidence that NRTIs cause long‐term health risks for cancer and mitochondrial disease. Thus, agents that mitigate toxicities of the current combination drug therapies are needed. Previous work had shown that the NRTI‐drug pair zidovudine (AZT)–didanosine (ddI) was highly cytotoxic and mutagenic; thus, we conducted preliminary studies to investigate the ability of the active moiety of amifostine, WR1065, to protect against the deleterious effects of this NRTI‐drug pair. In TK6 cells exposed to 100 μM AZT‐ddI (equimolar) for 3 days with or without 150 μM WR1065, WR1065 enhanced long‐term cell survival and significantly reduced AZT‐ddI‐induced mutations. Follow‐up studies were conducted to determine if coexposure to AZT and WR1065 abrogated the antiretroviral efficacy of AZT. In human T‐cell blasts infected with HIV‐1 in culture, inhibition of p24 protein production was observed in cells treated with 10 μM AZT in the absence or presence of 5–1,000 μM WR1065. Surprisingly, WR1065 alone exhibited dose‐related inhibition of HIV‐1 p24 protein production. WR1065 also had antiviral efficacy against three species of adenovirus and influenza A and B. Intracellular levels of unbound WR1065 were measured following in vitro/in vivo drug exposure. These pilot study results indicate that WR1065, at low intracellular levels, has cytoprotective and antimutagenic activities against the most mutagenic pair of NRTIs and has broad spectrum antiviral effects. These findings suggest that the activities have a possible common mode of action that merits further investigation. Environ. Mol. Mutagen. 2009. © 2009 Wiley‐Liss, Inc.
The Influence of e-Health Literacy, Subjective Health Status, and Health Information Seeking Behavior on the Internet on Health Promoting Behavior

본 연구는 성인 남녀의 e-헬스 리터러시, 주관적 건강상태, 인터넷에서의 건강정보 추구행위가 건강증진행위에 미치는 영향을 파악하기 위해 시도되었다. 본 연구의 대상은 강원도 G시에 거주하는 만 20~50대 성인 남녀 195명이였으며, 수집된 자료는 t-test, ANOVA, Pearson Correlation Coefficient, 다중선형회귀분석 방법을 이용하여 분석하였다. 대상자의 e-헬스 리터러시와 대상자의 주관적 건강상태는 높은 편 이었으며 인터넷에서의 건강정보추구 행위는 중간 정도였다. 건강증진행위 점수는 다소 낮았으며, 대인관계 영역이 가장 높고 신체활동 영역이 가장 낮았다. 일반적 특성에 따른 주요 변수들의 차이에서는 결혼여부, 건강관심 정도에 따라 e-헬스 리터러시에 유의한 차이가 있었으며, 성별, 건강관심 정도에 따라 주관적 건강상태에 차이가 있었고, 건강정보 추구행위, 건강증진행위에서는 건강관심 정도에 따른 차이를 보였다. 건강증진행위는 주관적 건강상태, e-헬스 리터러시, 건강정보 추구행위와 모두 유의한 정적 상관관계를 가지는 것으로 나타났다. 회귀분석 결과, 건강증진행위의 영향요인의 크기는 주관적 건강상태, 건강정보추구 행위, e-헬스 리터러시 순이었다. 이 모델은 건강증진행위를 33.0%의 설명력으로 예측하였다.
Inter-strand C-H...O hydrogen bonds stabilizing four-stranded intercalated molecules: stereoelectronic effects of O4' in cytosine-rich DNA.

DNA fragments with stretches of cytosine residues can fold into four-stranded structures in which two parallel duplexes, held together by hemiprotonated cytosine.cytosine+ (C.C+) base pairs, intercalate into each other with opposite polarity. The structural details of this intercalated DNA quadruplex have been assessed by solution NMR and single crystal x-ray diffraction studies of cytosine-rich sequences, including those present in metazoan telomeres. A conserved feature of these structures is the absence of stabilizing stacking interactions between the aromatic ring systems of adjacent C.C+ base pairs from intercalated duplexes. Effective stacking involves only the exocyclic keto groups and amino groups of the cytidine bases. The apparent absence of stability provided by stacking interactions between the bases in this intercalated DNA has prompted us to examine the available structures in detail, in particular with regard to unusual features that could compensate for the lack of base stacking. In addition to base-on-deoxyribose stacking and intra-cytidine C-H.O hydrogen bonds, this analysis reveals the presence of a hitherto unobserved, systematic intermolecular C-H.O hydrogen bonding network between the deoxyribose sugar moieties of antiparallel backbones in the four-stranded molecule.
Muscle fatigue and endurance during repetitive intermittent static efforts: development of prediction models

Localized muscle fatigue has received growing attention as a potential design variable and exposure metric in research towards prevention of musculoskeletal disorders in the workplace. While fatigue during sustained static work has been investigated extensively, effects during tasks comprising work–rest cycles are less clear. Work–rest models for static intermittent work have been presented in several reports, but the applicability is often limited to specific conditions. A study was conducted that facilitated a description of the relationships between static intermittent efforts and muscle endurance and fatigue. Exercises consisted of 1 h (maximum) of repetitive static arm abductions, involving a range of muscle contraction levels (10–30% maximum voluntary exertion), duty cycles (0.2–0.8) and cycle times (20–180 s). A between-subject central composite experimental design was used and 15 different exercise conditions were examined with six participants (three females and three males) for each. Along with endurance times, temporal changes related to fatigue were monitored using muscle strength, ratings of discomfort and electromyography (EMG) obtained from the middle-deltoid muscle during the contraction phase of the work cycles. The results of this study showed the influence of contraction level and duty cycle on the majority of fatigue measures used, while cycle time tended to affect EMG spectral measures. Using a response surface methodology, several fatigue prediction models and contour plots were developed that can be employed as an aid for design and evaluation of light repetitive static tasks. Good correspondence was generally found between discomfort rating and other measures of fatigue, suggesting the usefulness of this measure for rapid assessments of local fatigue in the workplace.
Online sentiment analysis in marketing research: a review

The explosion of internet-generated content, coupled with methodologies such as sentiment analysis, present exciting opportunities for marketers to generate market intelligence on consumer attitudes and brand opinions. The purpose of this paper is to review the marketing literature on online sentiment analysis and examines the application of sentiment analysis from three main perspectives: the unit of analysis, sampling design and methods used in sentiment detection and statistical analysis. ,The paper reviews the prior literature on the application of online sentiment analysis published in marketing journals over the period 2008-2016. ,The findings highlight the uniqueness of online sentiment analysis in action-oriented marketing research and examine the technical, practical and ethical challenges faced by researchers. ,The paper discusses the application of sentiment analysis in marketing research and offers recommendations to address the challenges researchers confront in using this technique. ,This study provides academics and practitioners with a comprehensive review of the application of online sentiment analysis within the marketing discipline. The paper focuses attention on the limitations surrounding the utilization of this technique and provides suggestions for mitigating these challenges.