Miracle-dz/UniFAR-FTUs huggingface dataset:
Species distribution and antifungal susceptibility pattern of Candida causing oral candidiasis among hospitalized patients

Background: Oral candidiasis is increasingly seen among hospitalized patients and is usually treated empirically. It can be the marker of systemic infection. Antifingal resistance is one of the emerging problems in candidiasis. Aim and Objectives: To study the distribution pattern of various Candida species among hospitalised patients with oral candidiasis, to detect the antifungal resistance among Candida and to assess the possible risk factors associated with those patients. Methods: Out of 300 patients screened, oral thrush material was collected from 36 patients having oral candidiasis. Candida spp. were isolated and identified. Antifungal susceptibility test was performed by disk diffusion method. Results: Candida albicans was the most frequently isolated species (64%). Highest resistance was seen with ketoconazole (18%). Except one C. tropicalis, all the isolates were sensitive to amphotericin B. All the patients were on broad spectrum antibiotic treatment. Diabetes mellitus was seen in 50 % of the patients. Other predisposing factors include tuberculosis, COPD, cancer and steroid treatment. Conclusion: Eventhough there is progressive shift from a predominance of C. albicans to non-albicans Candida species in candidiasis, C. albicans remains as the most important pathogen in oral candidiasis. Since azole resistance is increasing, accurate identification of Candida spp. and antifungal susceptibility testing is crucial for patient management and for facilitating hospital control measures.
THE BINARY NEUTRON STAR EVENT LIGO/VIRGO GW170817 A HUNDRED AND SIXTY DAYS AFTER MERGER: SYNCHROTRON EMISSION ACROSS THE ELECTROMAGNETIC SPECTRUM

We report deep Chandra, HST and VLA observations of the binary neutron star event GW170817 at t < 160 d after merger. These observations show that GW170817 has been steadily brightening with time and might have now reached its peak, and constrain the emission process as non-thermal synchrotron emission where the cooling frequency νc is above the X-ray band and the synchrotron frequency νm is below the radio band. The very simple power-law spectrum extending for eight orders of magnitude in frequency enables the most precise measurement of the index p of the distribution of non-thermal relativistic electrons N(γ) ∝ γ−p accelerated by a shock launched by a NS-NS merger to date. We find p = 2.17± 0.01, which indicates that radiation from ejecta with Γ ∼ 3 − 10 dominates the observed emission. While constraining the nature of the emission process, these observations do not constrain the nature of the relativistic ejecta. We employ simulations of explosive outflows launched in NS ejecta clouds to show that the spectral and temporal evolution of the nonthermal emission from GW170817 is consistent with both emission from radially stratified quasi-spherical ejecta traveling at mildly relativistic speeds, and emission from off-axis collimated ejecta characterized by a narrow cone of ultra-relativistic material with slower wings extending to larger angles. In the latter scenario, GW170817 harbored a normal SGRB directed away from our line of sight. Observations at t ≤ 200 days are unlikely to settle the debate as in both scenarios the observed emission is effectively dominated by radiation from mildly relativistic material. Subject headings: GW
AN EARTHQUAKE SOURCE SENSITIVITY ANALYSIS FOR TSUNAMI PROPAGATION

USAGE Permission is granted to copy this article for use in teaching and research. Republication, systematic reproduction, or collective redistribution of any portion of this article by photocopy machine, reposting, or other means is permitted only with the approval of The Oceanography Society. Send all correspondence to: info@tos.org or The Oceanography Society, PO Box 1931, Rockville, MD 20849-1931, USA. Oceanography THE OFFICIAL MAGAZINE OF THE OCEANOGRAPHY SOCIETY
Interactive comment on “ Ammonia emissions from cattle urine and dung excreted on pasture ” by J .

This paper presents results from a 12 day experiment to determine NH3 emissions from a circular pasture of about 800 m2 grazed for 3 days by 12 cattle. It is related to the publication of Laubach et al., Agricultural and Forest Meteorology 156, 1-17, 2012, and the main methodology is similar here. The vertical horizontal NH3 flux profile was measured by so-called Leuning samplers in the centre of a circular plot in order to apply the integrated horizontal flux (IHF) approach for emission determination. Feed (cut pasture) uptake was controlled and feed nitrogen content and other parameters were measured to describe the N intake and to relate measured NH3 emissions to the estimated excreted N amount. A bimodal emission course was observed, and with the help of control urine and dung patches and associated pH the authors attempt to distinguish between NH3 emissions from urine and dung. Finally, a simple flux resistance model is inferred and the resistance of the dung crust towards NH3 C5409
ACTIVITY RHYTHMS AND THE INFLUENCE OF SOME ENVIRONMENTAL VARIABLES ON SUMMER UNGULATE BEHAVIOUR

We have studied daily activity rhythms and time-budgets of four large herbivores (cattle, sheep, goats and chamois) which form a multi-species grazing system in a summer pastoral unit of the Central Pyrenees. Also, the influence of some environmental variables (altitude, slope and plant cover) on the main activities has been appraised. Grazing is the activity to which most time is dedicated in all the species: cattle 48%, sheep 53%, goats 55% and chamois 68%. Cattle is the species with the highest resting rate (41%) and sheep is the species spends most time walking (35%). Results suggest the existence of an inverse relationship between body size and grazing time. Cattle show two clear grazing peaks during the day at early morning and late evening. Contrary to this, sheep and chamois show a multimodal pattern, with some peaks for this activity throughout the day. Environmental factors clearly influence cattle and chamois activities. Sheep and goats show a less definite pattern in respect to environmental factors, probably because of their herded condition.
Can (Inter-party) Politics “Disappear”?1

Based on observational as well as experimental accounts, this meta-analytical article deals with the structure of opportunities and limitations that is encountered in party competition by political actors (especially parties, but, in more personalized contexts, also candidates) when they try to decide whether to prioritize between strategies based on the differentiation of positions on political issues and strategies based on factors that are not directly related to competing on issues. Further, the article outlines the mechanisms that serve to interconnect these two strategies and thus lead to a full-fledged political competition with sufficiently developed positional differentiation. In contrast, emphasizing the disappearance of “the politics of goals” in favour of “the politics of outcomes” is not, according to the current state of knowledge in the field, a rewarding strategy of political competition among parties.
A Study of the Therapeutic Effects of Vitamin E on Testicular Tissue Damage Caused by Fluoxetine

Objective: Fluoxetine is widely used in the treatment of neurological disorders. Hence, considering the adverse effects of this drug on the endocrine axes of the body is very important. Fluoxetine has been shown to cause significant changes in testicular tissue structure and sex hormones in rats. It seems that antioxidant compounds such as vitamin E can reduce free radicals and inhibit these changes. Therefore, the aim of this study is to investigate the therapeutic effects of vitamin E on testicular tissue damage caused by fluoxetine use. Materials and Methods: In the present study, 40 Wistar rats (weight = 250 ± 10 gr) were randomly divided into 4 groups; control group that received normal saline (with intraperitoneal (IP) method), fluoxetine group (n = 10) that received 10 mg/kg of fluoxetine (IP), vitamin E group (n = 10 that received 100 mg/kg of vitamin E (IP), and the treatment group that received both vitamin E (100 mg/kg) and fluoxetine (10 mg/kg) for 28 days. On the 28 th day of the study testis tissue was removed and sent to the pathology lab and blood samples were taken for analyzing of testosterone and total antioxidant capacity. Results: The highest testosterone levels are related to the control group and the lowest levels are related to the fluoxetine receiving group. Significant differences were observed between sperm density in the seminiferous tubes, spermatogonia cells, and primary spermatocyte, and leydig and sertoli cells in the experimental groups compared to the control group after a 28-day period. Conclusion: Fluoxetine can damage the leydig cells and decrease activity of testis and production of testosterone, but vitamin E can repair the leydig cells and reduce damages caused by fluoxetine.
SSII BMFsA ( 2 ool-o 7-olo 2 ) CON 7 RBUTEDARnCLE

Uhiversio, qfEastAsia, 2-1 Ibhinomiyagakuen-machi, Shimonoseki, Japan 7518503 Seinan Gakuin Uhiversipt 6-2-92 Nishijin, Sawara-im, Fukttoka, Japan 8140002 E-mail: yao@po.cc. toua-u.acjp (,eceived April 2Z2001 ) Abstract 7"is paper pmposed a metltod to extract and nieasure the peritoneuni automatically In this aigorithm, ,firstbl the iuput image is normalized and the ecige between the enipty area and the monolayer qf'the flat cells are detected. Tken, theperitoneum area is extracted tp, the using a thnee layer neural netu,ork. And then nJeasurement qlr theperitoneztm is performed, P}Zr tested this aigorithm tpi using the real-world image. The erperiment results show that this method is vei7, qi7icient and
Socio-Emotional Robot with Distributed Multi-Platform Neuromorphic Processing : (Invited Presentation)

Social robotics is a highly useful field that is rapidly growing. Advances in embedded systems and fields like neuromorphic computing provide hardware solutions for the computationally complex models needed to produce realistic, pro-social socio-emotional robots. This work details a robot which executes a simplified amygdala model to determine an emotional state from visual input and a subsequent behavioral response. Each nuclei of this model is processed on a different neuromorphic platform, including the SpiNNaker, Loihi, and Braindrop chips. Although simplified, this robot and its underlying model illustrate a proof of concept for more complicated and biologically-plausible socio-emotional robots.
An overlapping-generations model with search∗

Search is embedded in an overlapping-generations model. The young participate in a centralized market, and then are matched in pairs in a decentralized market. The old only participate in the centralized market. If the buyer’s bargaining power in pairwise trade is close to unity and if the old are risk averse, then the golden-rule rate of money transfer is positive. Such risk aversion, the pairwise meetings, and dependence of the young’s saving on the rate of return are necessary for this result. JEL classification: E30, E31, E40, E41
An Energy ‐ Efficient Strategy for Virtual Machine Allocation over Cloud Data Centers

With the increase in the scale of cloud data centers, more attention is being focused on the issue of energy conservation. In order to achieve greener, more efficient computing in cloud data centers, in this paper, we propose an energy-efficient Virtual Machine (VM) allocation strategy with an asynchronous multi-sleep mode and an adaptive task-migration scheme. The VMs hosted in a virtual cluster are divided into two modules, namely, Module I and Module II. The VMs in Module I are always awake, whereas the VMs in Module II will go to sleep independently, if possible. Accordingly, a queuing model with a partial asynchronous multiple vacations is established to capture the working principle of the proposed strategy. Using the method of a matrix-geometric solution, performance measures in terms of the average response time of tasks and the energy saving rate of the system are mathematically derived. Numerical experiments with analysis and simulation are provided to validate the proposed VM allocation strategy and to estimate the influence of system parameters on performance measures. Finally, a system cost function is constructed to trade off different performance measures, and an intelligent searching algorithm is employed to optimize the number of VMs in Module II and the sleeping parameter in the same time.
The abilities and some possible extensions of the Continuous Query Language

The CQL, Continuous Query Language is an expressive SQL-based declarative language for registering continuous queries against streams and updatable relations. CQL is suitable for data stream queries. There are situations when the queries operate on relational databases and on the data streams simultaneously. The execution of CQL query takes a long time (it may be several hours, days or even more). It is not unambiguous which semantic is suitable for the user when the database is updated during the execution of CQL query. For example, when we wish keep an eye on changing the value of an account while the official rates are updated, then CQL system must calculate with the retroactive effect of this update. Another semantic is reasoned when the prices are changed while we use CQL query for observing the trade of a supermarket. In this case the effect of the update is valid from the moment of update. In this paper we give a short description of CQL, characterisation of update-problems, and we give possible suggestions for the semantically extension of CQL. Additional interesting question is the explanation of the consistent state. In classical database theory it is an usually requirement that the “normal” state of a database is the consistent state. The consistency is not a permanent state, during the updates it may be damaged for a short time. Investigations were performed to find out what the effect of the inconsistent state on the currently operating CQL queries is.
Expression and function of the P2X7 receptor in monocytes from patients with Behçet’s disease

Background. P2X7 receptor is a nucleotide-gated ion channel involved in the inflammatory response triggered by passive release of ATP from damaged cells. It is expressed in monocytes and plays a key role in promoting the release of IL-1β. Behçet’s disease is a systemic immune-inflammatory disorder of unknown origin whose clinical manifestations include oral and genital ulcers, skin lesions, uveitis and arthritis. Since innate immunity activation and IL-1β release seem to play a relevant role in BD, we hypothesized a P2X7R involvement in the pathogenesis of the disease. Methods. PBMC, or isolated monocytes, were prepared from 18 BD patients and 17 healthy controls matched for age and sex. In these cells we evaluated: (i)P2X7R expression, and (ii) function, induced by P2X7 receptor stimulation, as determined by cytosolic free Ca influxes measurements and IL-1β release. Results. P2X7R expression and the amount of Ca 2+ influxes, induced by the selective P2X7R agonist BzATP, were higher in BD patients than in healthy controls monocytes. Moreover, in BD patients BzATP stimulation significantly enhanced the release of IL-1β from LPS-primed monocytes. Interestingly, we noted that BD patients treated with anti-TNFα drugs approached the P2X7R expression and function of healthy controls. In addition, TNFα incubation stimulated P2X7R expression and P2X7R-dependent Ca uptake in monocytes from healthy controls. Conclusions. Our results provide evidence that in monocytes from BD
Recent Statistical Developments in Bioequivalence Trials — A Review of the FDA Guidance*

This paper provides an overview of recent statistical developments in bioavailability and bioequivalence studies, including background, the fundamental bioequivalence concept, decision rules, and statistical methods for assessment of bioequivalence. Statistical issues addressed in the 1986 bioequivalence hearing and in the “Guidance on Statistical Procedures for Bioequivalence Studies” issued by the Division of Bioequivalence of the Office of Generic Drugs of the United States Food and Drug Administration (FDA) are discussed. These issues consist of the comparison of pharmacokinetic versus statistical models in determination of a proper scale for analyses and the impact of a significant sequence effect and outlying data on the evaluation of bioequivalence. Other issues such as the concept of population and individual bioequivalence and their relationship, the application of a repeated crossover design to bioequivalence assessment, alternative bioequivalence measures, and statistical procedures of assessing bioequivalence with more than two formulations are also addressed.
Low molecular weight heparin gels, based on nanoparticles, for topical delivery

A commercial suspension of nanoparticles (Eudragit® RS 30D) was used to manufacture a gel for topical application. Gels were prepared by mixing a polycationic polymer (Eudragit® RS 30D) and a low molecular weight heparin (LMWH), an antithrombotic agent. Gels formed spontaneously at a ratio of 1:1 as a result of electrostatic interactions between the polyanionic drug and the polycationic polymer. Different types of heparin were used: Bemiparin, Enoxaparin (Lovenox®), Nadroparin (Fraxiparin®) and Tinzaparin (Innohep®). Several LMWH concentrations were tested. Rheological measurements were performed to investigate the gel behavior. Gel formation was confirmed by dynamic rheological measurements as the ′ ′′ el
J un 2 01 0 Pulsars as gravitational wave detectors

Pulsar timing array projects are carrying out high precisio n observations of millisecond pulsars with the aim of detecting ultra-low f requency ( ∼ 10−9 to 10−8 Hz) gravitational waves. We show how unambiguous detection s of such waves can be obtained by identifying a signal that is correlated be twe n the timing of different pulsars. Here we describe the ongoing observing p rojects, the expected sources of gravitational waves, the processing of the data a nd the implications of current results.
Bounds on Special Subsets in Graphs, Eigenvalues and Association Schemes

We give a bound on the sizes of two sets of vertices at a given minimum distance in a graph in terms of polynomials and the Laplace spectrum of the graph. We obtain explicit bounds on the number of vertices at maximal distance and distance two from a given vertex, and on the size of two equally large sets at maximal distance. For graphs with four eigenvalues we find bounds on the number of vertices that are not adjacent to a given vertex and that have μ common neighbours with that vertex. Furthermore we find that the regular graphs for which the bounds are tight come from association schemes.
Novel Bandwidth-Agile Bandpass Filter using Defected Ground Structure

A novel microstrip bandpass filter (BPF) with tunable passband width using defected ground structure (DGS) is proposed. In this DGS, a pair of slotted radial stubs that can be equivalent to a capacitor and an inductor in parallel are incorporated to realize an attenuation pole (AP) in the higher stopband of the proposed BPF without increasing the circuit size, and the equivalent circuit of the BPF is also given. By properly adding varactor diodes into the slotted stubs to tune the equivalent capacitance of the stubs, the corresponding AP can be shifted, and then the passband width of the BPF can be accordingly tuned, leading to a bandwidth-agile BPF. Index Terms – Bandpass filter (BPF), defected ground structure (DGS), and tunable filter.
Open Archive TOULOUSE Archive Ouverte (OATAO)

Linked Open Data (LOD) become one of the most important sources of information allowing enhancing business analyses based on warehoused data with external data. However, Data Warehouses (DWs) do not directly cooperate with LOD datasets due to the differences between data models. In this paper, we describe a conceptual multidimensional model, named Unified Cube, which is generic enough to include both warehoused data and LOD. Unified Cubes provide a comprehensive representation of useful data and, more importantly, support well-informed decisions by including multiple data sources in one analysis. To demonstrate the feasibility of our proposal, we present an implementation framework for building Unified Cubes based on DWs and LOD datasets.
persyaratan habis pakai produk untuk komponen otomotif dengan mengurangi konsumsi polimer. Indonesia merupakan salah satu negara yang membudidayakan kelapa sawit terbesar di dunia. Kelapa sawit mengandung selulosa yang cukup tinggi sehingga dapat dimanfaatkan sebagai penguat pada komposit polimer. T

Abstrak—Komposit berpenguat nanofiller merupakan salah satu material yang sedang dikembangkan. Salah satu aplikasinya dapat digunakan sebagai bahan akustik. Penggunaan serat alam sebagai penguat pada komposit mendukung regulasi tentang persyaratan habis pakai produk untuk komponen otomotif dengan mengurangi konsumsi polimer. Indonesia merupakan salah satu negara yang membudidayakan kelapa sawit terbesar di dunia. Kelapa sawit mengandung selulosa yang cukup tinggi sehingga dapat dimanfaatkan sebagai penguat pada komposit polimer. Tujuan dari penelitian ini adalah menganalisis ikatan kimia serat setelah diberi perlakuan kimia. Pengujian yang dilakukan dalam penelitian yaitu FTIR. Pembuatan nanoselulosa dengan menggunakan tiga tahap perlakuan kimia yaitu alkalisasi, bleaching dan hidrolisis asam. Setelah dilakukan tiga tahap perlakuan kimia pada serat tandan kosong kelapa sawit, hasil FTIR menunjukkan tiga daerah serapan utama yaitu 3288.08 cm , 1636.43 cm dan 1089.92 cm yang menunjukkan ikatan O-H stretching, O-H deformasi dan C-C stretching. Daerah serapan yang muncul menunjukkan bahwa telah dihasilkan selulosa dan kandungan lignin menghilang.
Differential diagnosis in the memory clinic : Exploring the value of improved neuropsychological examination Rienstra

Background: Studies investigating relations between cognitive performance and brain atrophy in patients with mild cognitive impairment (MCI) have been conducted in highly selected samples. This methodological strictness does however not reflect clinical practice, and limits the generalizability of these studies to the MCI population at large. Objective: To identify the cerebral morphometric correlates of cognitive deficits in a large, unselective sample of elderly patients referred to memory clinics. Methods: Participants (N=126) underwent structural, high-resolution Magnetic Resonance Imaging (MRI) and a comprehensive neuropsychological examination evaluating several cognitive domains. Whole-brain voxel-based morphometry was performed to examine relationships of cognitive functioning with regional grey matter (GM) volume. Results: Significant correlations were found between cognitive functioning, irrespective of cognitive domain, and regional GM volume in the temporal lobes, in particular the bilateral middle temporal gyri. Cognitive function in non-memory domains was correlated with regional brain morphology outside the temporal lobes only when studied in isolation. The primary memory impairment, characteristic for MCI patients, remained specifically related to lower volume of the left hippocampus, even when variance in other cognitive domains was accounted for. Conclusion: Our results suggest that correlations of volumetric data and cognitive data in memory clinic patients reflect the primary neurodegenerative pathology, i.e. temporal lobe atrophy. The relation between impaired memory and temporal lobe atrophy is much stronger in these patients than other brain-cognition relationships. Anne_brains_proefschrift_2_corr_NOBASE_2. indd 80 24-11-14 14:38 81 Exploring the value of improved neuropsychological examination