Miracle-dz/UniFAR-FTUs huggingface dataset:
Uso de la realidad virtual en el control del nivel de dolor asociado a la venopunción en pacientes oncológicos pediátricos

Introduccion: Dentro de los procesos dolorosos que se realizan de forma rutinaria en ninos y adolescentes que padecen cancer, encontramos la venopuncion. En los ultimos anos la evidencia ha demostrado que la realidad virtual como metodo de distraccion para el manejo del dolor en este tipo de procedimientos es efectiva. Objetivo: El objetivo de este trabajo de final de grado es evaluar la efectividad de un programa de control del dolor basado en realidad virtual dirigido a ninos oncologicos, hospitalizados en el Hospital Sant Joan de Deu de Barcelona, sometidos a una venopuncion. Metodologia e intervencion: Esta intervencion va dirigida a ninos oncologicos susceptibles de ser sometidos a una venopuncion. En este trabajo se plantea un estudio experimental aleatorio con un grupo de estudio formado por pacientes sometidos a una venopuncion con realidad virtual (se les introducira en el entorno virtual de la app RUSH) y un grupo control que recibira el tratamiento estandar durante el proceso. La edad de los participantes oscila entre 13 y 17 anos y se anotara el nivel de dolor de los pacientes segun la Escala Visual Analogica (EVA) antes y despues de la venopuncion. Se realizara un analisis estadistico parametrico descriptivo y bivariante. Discusion: La realidad virtual ha demostrado en numerosas ocasiones su eficacia y que es una tecnica no farmacologica optima, debido a su coste y a sus escasos efectos secundarios, para el control del nivel del dolor a pesar de que todavia es necesaria mas investigacion futura.
Interrelationships Among Insulin's Antilipolytic and Glucoregulatory Effects and Plasma Triglycerides in Nondiabetic and Diabetic Patients With Endogenous Hypertriglyceridemia

We tested the hypothesis that the previously observed association among hypertriglyceridemia, hyperinsulinemia, and insulin resistance could be explained by a defect in insulin's antilipolytic effect. Insulin action was measured in 10 nondiabetic and 8 diabetic patients with hypertriglyceridemia (fasting plasma triglyceride 800 ± 154 and 1105 ± 445 mg/dl, respectively, P NS; fasting plasma glucose 99 ± 3 and 161 ± 12 mg/dl, respectively, P < .001) and in 8 weight-matched normolipemic nondiabetic individuals (fasting plasma triglyceride and glucose 110 ± 21 and 91 ± 3 mg/dl). The slope of the decay in plasma free fatty acid (FFA) during insulin infusion was used as an index of insulin's antilipolytic effect. Insulin stimulation of glucose uptake in vivo during intravenous hyperinsulinemic clamp and in vitro in adipocytes were measures of insulin's glucoregulatory action. Both glucoregulatory and antilipolytic effects were similarly reduced in both hypertriglyceridemic groups compared with normal subjects. The plasma triglyceride concentration correlated positively with the slope of FFA suppression by insulin (r = .81, P < .0001) and the fasting FFA concentration (r = .65, P < .0001). In multiple linear regression analysis, insulin's antilipolytic effect and the fasting FFA concentration explained 83% of the variation in the plasma triglyceride concentration. These associations were independent of insulin's glucoregulatory effect and the fasting plasma insulin concentration. The data indicate that patients with endogenous hypertriglyceridemia are resistant to both the antilipolytic and glucoregulatory actions of insulin and that increased flux of FFA as a result of the latter, rather than hyperinsulinemia, is responsible for elevation of very-low-density lipoprotein production. Finally, we suggest that previous inconsistent results regarding insulin's antilipolytic effect in obesity and non-insulin-dependent diabetes mellitus could be related to variation in the triglyceride concentrations of the study populations.
Learning to Align Semantic Segmentation and 2.5D Maps for Geolocalization

We present an efficient method for geolocalization in urban environments starting from a coarse estimate of the location provided by a GPS and using a simple untextured 2.5D model of the surrounding buildings. Our key contribution is a novel efficient and robust method to optimize the pose: We train a Deep Network to predict the best direction to improve a pose estimate, given a semantic segmentation of the input image and a rendering of the buildings from this estimate. We then iteratively apply this CNN until converging to a good pose. This approach avoids the use of reference images of the surroundings, which are difficult to acquire and match, while 2.5D models are broadly available. We can therefore apply it to places unseen during training.
A comparison of a printed patient summary document with its electronic equivalent: early results

Clinicians are always searching for efficient access to clinical data. The Regenstrief Medical Record System has a printed report that fills this niche: Pocket Rounds. Handheld computers may offer an alternative, but it is unclear how effectively a handheld computer can display such data. We surveyed residents and students on the general medicine services for their opinions regarding Pocket Rounds. Those with handheld computers were given access to an electronic version of Pocket Rounds-e-Rounds. We surveyed the subjects who used e-Rounds for their opinions on the electronic format and how it compared to paper. Users overall satisfaction with Pocket Rounds was 5.8 on a seven-point scale. User s overall satisfaction for e-Rounds was 5.6 on a seven-point scale. The most useful function was retrieval of lab data for both modalities. The results suggest that the electronic format is a viable alternative to paper. Further evaluation is needed, and we plan a prospective controlled trial to study this further.
PENINGKATAN MOTIVASI BELAJAR DAN KEMAMPUAN BERLARI MELALUI MODEL PERMAINAN PERLOMBAAN PADA SISWA KELAS 3 SD NEGERI BANDUNG WONOSEGORO BOYOLALI

Tujuan penelitian ini adalah untuk meningkatkan motivasi belajar dan kemampuan berlari pada siswa kelas 3 SD Negeri Bandung Wonosegoro Boyolali tahun pelajaran 2014/2015.Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK),yang dilakukan dua siklus dengan prosedur penelitian adalah perencanaan tindakan, pengamatan, dan refleksi. Tehnik pengumpulan data menggunakan: observasi, wawancara, dan dokumentasi.Hasil penelitian menunjukkan temuan bahwa model Permainan dan Perlombaan dapat: 1). Meningkatkan motivasi belajar Penjasorkes materi Pola gerak Lokomotor berlatih lari pada siswa kelas 3 SD Negeri Bandung Wonosegoro Boyolali. Persentase kenaikan motivasi belajar siswa sebesar 3,15 (16.44%) untuk siklus 1 dan2.73 ( 10.62%) untuk siklus 2, 2) Meningkatkan kemampuan siswa dalamberlari, siswa berusaha menggunakan kemampuan yang dimilikinya untuk memenangkan perlombaan. Persentase kenaikan kemampuan belajar siswa sebesar10.69% untuk siklus 1 dan13.15% untuk siklus 2. 3) Meningkatkan persentase jumlah siswa yang mencapai ketuntasan belajar minimal (KKM) berikut: pada kondisi awal, persentase pencapaian KKM sebesar25.00% (8 siswa), pada siklus 1 persentase meningkat menjadi 55.56% ( 20 siswa), dan siklus 2 persentase jumlah siswa yang mencapai KKM meningkat menjadi 84.37% (27siswa)
Convergence of 60 GHz Radio Over Fiber and WDM-PON Using Parallel Phase Modulation With a Single Mach–Zehnder Modulator

We propose a converged radio over fiber and wavelength division multiplexing passive optical networks (WDM-PON) system compatible with wired and 60 GHz band wireless transmission by implementing two-band modulation with a single Mach-Zehnder modulator as parallel phase modulators. In this paper, broadband millimeter wave generation, which is compliant with the ECMA 387 standard, and 2.5 Gbps baseband transmission, which feeds up the requirement of fiber-to-the-home, are simultaneously realized after 25 km long optical fiber transmission. Furthermore, the interference between RF and baseband modulations is theoretically and experimentally investigated. The RF modulation impacts to the baseband signal for different RF modulation formats are deeply investigated.
CNP is required for maintenance of axon–glia interactions at nodes of Ranvier in the CNS

Axoglial interactions underlie the clustering of ion channels and of cell adhesion molecules, regulate gene expression, and control cell survival. We report that Cnp1‐null mice, lacking expression of the myelin protein cyclic nucleotide phosphodiesterase (CNP), have disrupted axoglial interactions in the central nervous system (CNS). Nodal sodium channels (Nav) and paranodal adhesion proteins (Caspr) are initially clustered normally, but become progressively disorganized with age. These changes are characterized by mislocalized Caspr immunostaining, combined with a decrease of clustered Na+ channels, and occur before axonal degeneration and microglial invasion, both prominent in older Cnp1‐null mice. We suggest that CNP is a glial protein required for maintaining the integrity of paranodes and that disrupted axoglial signaling at this site underlies progressive axonal degeneration, observed later in the CNS of Cnp1‐null mice. © 2005 Wiley‐Liss, Inc.
Circular polarization rectangular Dielectric Resonator Antenna for UHF RFID applications

A low profile circularly polarized RFID (radio frequency identification) reader antenna is designed and analysed for operation at the European ultra-high frequency (UHF) band, ranging from 865-868 MHz. The proposed Dielectric Resonator Antenna (DRA) is composed of microstrip line/slot feed and a rectangular dielectric resonator made from a high-permittivity (εr = 30). The simulated results show satisfactory performance versus size. The antenna works from 857 to 885 MHz, thus covering the European UHF RFID Band, and its circularly polarized radiation pattern provides a 3.75 dBi realized gain.
Analysis of the Effect of Distance Metric across Languages on Verse Similarity in the Qur ' an

Text similarity measures have been widely studied and used in machine learning and information retrieval for many years. However, few applications of text similarity have dealt with multi-lingual translations of a specific document. Additionally, the growing number of texts with more translations being generated increases the challenge of distinguishing or identifying the similarity and differences between texts across different documents. In this article, we employ different text similarity measures to delve into the problem of text similarity in the context of multi-lingual representations of the Qur'an. Four semantic translations of the Qur'an are used for comparative study and analysis. We compare and contrast the effect of applying five similarity measures across these representations. We analyze the results along two classes namely: identical verse pairs and similar verse pairs. Our analysis provides helpful observations about the impact of the five distance metrics for verse similarity in the Qur'an across different languages.
The Value of “Multimodal” or “Balanced Analgesia” in Postoperative Pain Treatment

reatment of postoperative pain is provided for humanitarian reasons and to alleviate nocicepT tion-induced responses, such as the endocrine metabolic response to surgery, autonomic reflexes with adverse effects on organ function, reflexes leading to muscle spasm, and other undesirable results (1). During the last decade there has been a virtual explosion in our knowledge of basic pain physiology (2,3), but the implications for clinical practice have been less substantial. The explanation for the discrepancy between the fast progress in basic pain pathophysiology and the rather slow advances in providing optimal postoperative pain treatment may be several, but one important factor may be that more than 95% of the literature on postoperative pain treatment has considered unimodal treatment. We have emphasized previously that total or optimal pain relief allowing normal function can not be achieved by a single drug or method without major strain on equipment and surveillance systems or without significant side effects (4). Therefore, we have recommended combined analgesic regimens (balanced analgesia) or a multimodal approach to the treatment of postoperative pain (4). The rationale for this strategy is achievement of sufficient analgesia due to additive or synergistic effects between different analgesics, with concomitant reduction of side effects, due to resulting lower doses of analgesics and differences in side-effect profiles. We summarize here the existing knowledge concerning the efficacy of analgesic combination therapy from postoperative pain studies. The effects on postoperative outcome are not included, because of lack of sufficient studies. We also exclude obstetric and pediatric pain, which may represent special pain entities and solutions for treatment, although they obviously share many of the problems of general postoperative pain. Primary emphasis will be placed on moderate and severe pain and the use of and need for
Protein import into chloroplasts involves redox‐regulated proteins

Pre‐protein translocation into chloroplasts is accomplished by two distinct translocation machineries in the outer and inner envelope, respectively. We have isolated the translocon at the inner envelope membrane (Tic complex) by blue‐native PAGE and describe a new Tic subunit, Tic62. Tic62, together with Tic110 and Tic55, forms a core translocation unit. The N‐terminus of Tic62 shows strong homologies to NAD(H) dehydrogenases in eukaryotes and to Ycf39‐like proteins present in cyanobacteria and non‐green algae. The stromal‐facing C‐terminus of Tic62 contains a novel, repetitive module that interacts with a ferredoxin‐NAD(P)+ oxidoreductase. Ferredoxin‐NAD(P)+ oxidoreductase catalyses the final electron transfer of oxygenic photosynthesis from ferredoxin to NAD(P). Substrates that interfere with either NAD binding, such as deamino‐NAD, or influence the ratio of NAD(P)/NAD(P)H, such as ruthenium hexamine trichloride, modulate the import characteristics of leaf‐specific ferredoxin‐NAD(P)+ oxidoreductase isologues differently. We conclude that the Tic complex can regulate protein import into chloroplasts by sensing and reacting to the redox state of the organelle.
Stopping power for low-velocity Mg ions in Si, Ge, and GaAs.

The stopping power for {sup 26}Mg ions in Si, Ge, and GaAs has been studied in the energy region 0--0.8 MeV/nucleon by application of the inverted-Doppler-shift attenuation-analysis method. Compared to the commonly used empirical electronic stopping power by Ziegler, Bierscak, and Littmark, significant deviations and a different velocity dependence were obtained. The electronic stopping power was determined to an accuracy of {plus minus}5%. The experimental nuclear stoping power was taken into account in the deduction of the electronic stopping power.
[Attention and neglect: neurological basis, assessment and disorders].

OBJECTIVE Attention phenomenology is a wide subject, in this revision we will explain attention and its relationship with behavioral neglect. DEVELOPMENT Selective attention is the ability to throw the focus of awareness toward behaviorally relevant events in the personal and extrapersonal space. Severe alteration of these mechanisms constitutes unilateral neglect in patients with contralateral brain damage. Unilateral neglect is one of the most behaviorally devastating syndrome. There are different behavioral neglect: attentional (perceptual), intentional (motor), motivational and representational aspects of unilateral neglect. Left side neglect after right hemisphere lesions is more common (31 to 46%) than right sided neglect following lesions in the left hemisphere (2 to 12%). CONCLUSION One year after a cerebrovascular accident only 1/3 of the patients with unilateral neglect persist with this handicap.
A novel image processing pipeline for assessing volumetric changes to grey matter in ex-vivo brain tissue

Recently, Magnetic Resonance Imaging (MRI) has found great traction in monitoring the effects of Caloric Restriction (CR) on the brain, specifically gray matter. However, there are no streamlined, simple pipelines in existence to analyze data generated from these kinds of MRI studies. Therefore, my hypothesis is two-fold: the first part being the development of a dynamic and straightforward image processing pipeline, which I have tailored to fit the unique needs of the CR data involved in this study. This data brings me to the second part of my hypothesis, which is to use that pipeline to highlight the decreased attenuation in grey matter induced by long-term CR. In order to test the second portion of my hypothesis, T1/MPRAGE scans were collected from 17 male Rhesus Macaques, half of which were maintained on a 30% reduced calorie diet for an average of 22 years, starting around age 3. Using this basis, the inherent properties of the MR images were exploited by the novel pipeline, and used to analyze whether or not CR reduces the attenuation of grey matter atrophy, with regards to aging.
Dose-Dependent Effect of an Oral Adsorbent, AST-120, in Patients with Early Chronic Renal Failure

We evaluated the dose dependence of an oral adsorbent, AST-120, in 31 patients with early chronic renal failure (baseline serum creatinine: 1.2–3.0 mg/dl). Twenty-three patients were given AST-120 and eight patients were not. AST-120 was administered at three different maintenance doses, < 3.0 g, 3.0 g and 6.0 g/day, according to patients' ability to tolerate treatment. The treatment period was 12 months. The slope of the reciprocal of serum-creatinine concentration versus time was calculated to assess the progression of renal failure. This slope became significantly less steep after AST-120 treatment at 6.0 g/day, but did not change significantly at the other doses. These findings suggest that 6.0 g/day of AST-120 may delay the initiation of dialysis in patients with early chronic renal failure.
Evidence for the Involvement of Dopamine Transporters in Behavioral Stimulant Effects of Modafinil

Modafinil is prescribed for numerous medical conditions, but the drug's mechanism of action is unclear. Here, we examined the interaction of modafinil with receptors and transporters in vitro and compared pharmacological effects of the drug with those produced by indirect dopamine (DA) agonists 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR12909) and (+)-methamphetamine (METH). Modafinil was screened at various receptors and transporters using binding assays. Transporter-mediated uptake and release were examined in rat brain synaptosomes. Effects of modafinil on motor activity and neurochemistry were determined in rats undergoing in vivo microdialysis in nucleus accumbens. Of the receptors and transporters assayed, modafinil displayed measurable potency only at DA transporters (DAT), inhibiting [3H]DA uptake, with an IC50 value of 4.0 μM. Accordingly, modafinil pretreatment (10 μM) antagonized METH-induced release of the DAT substrate [3H]1-methyl-4-phenylpyridinium. Intravenous modafinil (20 and 60 mg/kg) produced dose-dependent increases in motor activity and extracellular DA, without affecting serotonin (5-HT). Analogous results were observed for GBR12909 (1 and 3 mg/kg), whereas METH (0.3 and 1 mg/kg) increased DA and 5-HT. Locomotor effects of all drugs were positively correlated with dialysate DA (P < 0.001). Interestingly, modafinil pretreatment reduced METH-induced ambulation and DA release. Our data show that modafinil interacts with DAT sites in rat brain, a property shared with agonist medications under investigation for treating cocaine dependence. Nondopaminergic mechanisms may also contribute to the pharmacology of modafinil. Finally, the results suggest that modafinil should be tested as an adjunct for treating METH addiction.
Dimensions of Psychopathy and their Relationships to Cognitive Functioning in Children

Individuals with psychopathic traits are hypothesized to be free of intellectual deficits and possibly even to exhibit good cognitive abilities. Previous studies, based on clinical and incarcerated youth, have shown inconsistent findings. We investigated the relationships between different dimensions of psychopathy (callous/unemotional traits, narcissism, impulsivity) and cognitive abilities in a large population-based sample of children (age 9, N = 4,713). Findings indicated a positive relationship between narcissism and both verbal and nonverbal abilities, even after accounting for conduct problems and hyperactivity. Callous/unemotional traits and impulsivity were negatively related to both types of cognitive abilities but did not remain significant after accounting for conduct problems and hyperactivity. Interactions between gender and the dimensions of psychopathy were not significant.
Muscle spindle feedback differs between the soleus and gastrocnemius in humans

The Hoffmann (H) reflex and motor (M) response were studied in soleus and gastrocnemius during voluntary contraction in eight male volunteers. Aims: To determine if the strength of spindle input to the muscles is the same. To assess if the M response size changes during contraction. Results: The size of the maximum M response (M max) changed during contraction in each subject. Hence, all H reflex measurements were normalized to the M max at each level of contraction for each subject. The largest H/M max was bigger in soleus than gastrocnemius at every contraction level. The overall largest H/M max for soleus (97%) and gastrocnemius (55%) were achieved at 40 and 100% maximum voluntary contraction (MVC), respectively. Conclusion: Soleus receives greater spindle feedback than the gastrocnemius both at rest and during voluntary contraction.
Fairness in Reinforcement Learning

2(1 ) , via two applications of the summation formula for geometric series. Proof of Theorem 3. We prove Theorem 3 for the special case of k = 2 first. Consider coupling the run of a fair algorithm L on both M(0.5) and M(1). To achieve this, we can fix the randomness of L up front, and use the same randomness on both MDPs. The set of observations and hence the actions taken on both MDPs are identical until L reaches state sn. Until then, with probability at least 1 , L must play L and R with equal probability in order to satisfy fairness (since, for M(0.5), the only fair policy is to play both actions with equal probability at each time step). We will upper-bound the optimality of uniform play and lower-bound the number of rounds before which sn is visited by uniformly random play. Let f = d 1
Comparison of the population genetics and densities of five Pinanga palm species at Kuala Belalong, Brunei

This study investigated the effect of population density on the population genetic structure of five co‐occurring congeneric understorey palm species: Pinanga aristata, P. sp. aff. brevipes, P. dumetosa, P. tenella var. tenella and P. veitchii, all endemic to northern Borneo. The average population densities of the study species varied across a wide spectrum, ranging from 343 (plants per ha) in P. tenella to 10 (plants per ha) in P. veitchii. All species of Pinanga palms studied had quite high levels of genetic diversity (HE: 0.379, 0.256, 0.294, 0.133, 0.352). Genetic diversity (HE) was correlated with population density (D;rs = − 0.433, P < 0.01) and the average distance to the nearest conspecific neighbour (NN;rs = 0.576, P < 0.001) such that the most‐dense species had less genetic diversity and the less‐dense species had greater genetic diversity. Gene flow (Nm) among populations approximately followed a gradient of increasing species density and abundance, such that the most common species P. dumestosa had the greatest gene flow (Nm = 2.268) between its populations and the rarest, most sparsely distributed species P. sp. aff. brevipes had the lowest (Nm = 0.698). All species of Pinanga were effectively inbred (F: 0.760, 0.856, 0.640, 0.753, 0.674). The amount of homozygosity and inbreeding (HO, F) were not correlated (P > 0.05) with population density (D) or the distance between nearest neighbouring plants of the same species (NN).