Miracle-dz/UniFAR-FTUs huggingface dataset:
Global transcriptome profile of rice root in response to essential macronutrient deficiency

Deficiency of the three essential macronutrients, nitrogen, phosphorus and potassium, leads to large reduction in crop growth and yield. To characterize the molecular genetic basis of adaptation to macronutrient deprivation, we performed microarray analysis of rice root at 6 and 24 h after nitrogen, phosphorus and potassium deficiency treatments. The transcriptome response to nitrogen depletion occurred more rapidly than corresponding responses to phosphorus and potassium deprivation. We identified several genes important for response and adaptation to each nutrient deficiency. Furthermore, we found that signaling via reactive oxygen species is a common feature in response to macronutrient deficiency and signaling via jasmonic acid is associated with potassium depletion response. These results will facilitate deeper understanding of nutrient utilization of plants.
Monitoring Risks in Association With Exposure Levels Among Wastewater Treatment Plant Workers

Objective: To investigate the relationship between exposure to hydrogen sulfide and endotoxin during specific job tasks and health symptoms among wastewater treatment plant (WWTP) workers. Methods: The exposure levels for specific tasks were measured by personal monitoring. The health symptoms of WWTP workers were compared with those of water treatment plant workers through a questionnaire survey. Results: Exposure levels for all monitored tasks were less than 1 ppm for hydrogen sulfide and 91 EU/m3 (endotoxin units/m3) for endotoxin. Statistically higher odds ratios of respiratory, ocular and skin irritation, neurology, and gastrointestine symptoms were shown among WWTP workers compared with water treatment plant workers. Tasks related to sludge handling and plant inspection showed statistically significant associations with memory/concentration difficulties, throat irritation, and stomach pain. Conclusions: These results suggest that exposure control programs for specific job tasks and work locations are needed.
Chirurgie augmentée : un cas de réalité augmentée ; Conception et réalisation centrées sur l'utilisateur. (Augmented Surgery : an Augmented Reality Case Study ; User-Centred Design and Realization)

Les travaux pluridisciplinaires de cette these, contribuent a deux domaines : les Interfaces Homme-Machine (IHM), en particulier la Realite Augmentee (RA), et les Gestes Medico-Chirurgicaux Assistes par Ordinateur (GMCAO), domaine concret de mise en oeuvre de la RA. La contribution est double : d'une part elle enrichit et organise les concepts d'IHM pour la RA en adoptant un point de vue centre sur la tâche, et d'autre part elle ameliore l'utilisabilite par les cliniciens des systemes de GMCAO. La fusion du monde reel et du monde virtuel ouvre des voies nouvelles pour la conception de systemes de RA, comme les systemes de GMCAO. Mais les limites sont mal cernees. Dans ce contexte, nous avons identifie des caracteristiques intrinseques des systemes de RA et etabli un espace taxinomique. Afin de caracteriser plus finement la dualite de l'interaction (Utilisateur-Monde Reel et Utilisateur-Monde Virtuel), nous avons defini la notation ASUR. Pour decrire l'interaction, ASUR identifie les entites intervenant dans le systeme, en particulier les adaptateurs, composants ASUR realisant le lien entre les deux mondes. L'utilisation d'ASUR, par ces aspects descriptifs, taxinomiques et conceptuels constitue la base de notre demarche de conception ergonomique et logicielle de systemes de RA. Cette demarche se fonde en outre sur l'etude de proprietes ergonomiques au sein de la description ASUR d'un systeme et sur l'adaptation du modele d'architecture PAC-Amodeus aux systemes de RA. En collaboration avec le chirurgien, nous avons applique et teste nos resultats methodologiques sur une application concrete de chirurgie cardiaque. Cette application, CASPER, assiste le chirurgien lors de la realisation d'une ponction pericardique, en lui procurant des informations de guidage du geste clinique sur un ecran. Une re-conception de CASPER nous a amene a implementer un casque semi-transparent permettant de visualiser ces informations directement sur le patient.
Design of high order modulation backscatter wireless sensor for passive IoT solutions

Fully passive wireless networks are an enable for the internet of things. One of the hypothesis for this passive network implementation is to use backscatter radio nodes. Nevertheless, the traditional approach is to use ASK or PSK backscatter solutions that limits the data rate of the sensors, since it transfers only one bit per symbol period. In order to overcome these limitation, in this paper we propose a novel passive wireless sensor network based in 4-QAM backscatter modulation. The design strategy for high level order backscatter modulations will be explained and a design approach will be presented in this manuscript.
Chronic lymphocytic leukaemia skin infiltrates affecting prominent parts of the face and the scalp

Chronic lymphocytic leukaemia (CLL) infiltrating the skin is uncommon and can present in different forms. We report a case of CLL infiltrating the prominent parts of the face and the scalp. A 63‐year‐old male with a 10‐year history of CLL presented with plum‐coloured swelling of the skin of the ears, eyebrows, tip of the nose and the scalp. Histopathology showed dense sheets of lymphoid infiltrate of the dermis which stained positive with B‐cell markers CD20 and CD5 in keeping with the infiltrate of CLL.
Localizing Bugs in Programs - Or How to Use a Program's Constraint Representation for Software Debugging?

A method of communicating data between first and second communication apparatus having the steps of transmitting line current from the first communication apparatus to a transmission line interconnecting the first and second communication apparatus, the line current being controlled at an analog value representing analog data and having superimposed thereon a digital signal representing digital data, receiving at the second communication apparatus the analog and digital data transmitted by the first communication apparatus, controlling the transmission line voltage at an analog value for transmitting analog data from the second communication apparatus to the first communication apparatus and superimposing on the voltage containing the analog data a digital signal representing digital data, and receiving at the first communication apparatus the analog and digital data transmitted by the second communication apparatus.
Unravelling the moderating effects of size and experience on product innovations and exports: a study in a medium knowledge-intensive industry

This paper contributes to improve our knowledge on the important role of product innovation in export strategy by introducing the moderating effects of organizational variables. We argue that in a medium knowledge-intensive industry, these variables might strengthen the relationship between innovations and exports. Research on innovation and export strategy has addressed these issues increasingly during last decades; however, the divergence on the empirical approaches difficult the understanding of the linkages among variables, which are highly dependent on the industry technological characteristics. We carry out a time-lagged study using the literature-based innovation output (LBIO) method to account for product innovations and its degree of complexity during the period from 2000 to 2007. Our results evidence that, when considering the moderating role of size and experience, the influence of innovations on exports becomes stronger. Important implications for researchers, managers and policy makers arise from these findings.
Several Archaeal Homologs of Putative Oligopeptide-Binding Proteins Encoded by Thermotoga maritima Bind Sugars

ABSTRACT The hyperthermophilic bacterium Thermotoga maritima has shared many genes with archaea through horizontal gene transfer. Several of these encode putative oligopeptide ATP binding cassette (ABC) transporters. We sought to test the hypothesis that these transporters actually transport sugars by measuring the substrate affinities of their encoded substrate-binding proteins (SBPs). This information will increase our understanding of the selective pressures that allowed this organism to retain these archaeal homologs. By measuring changes in intrinsic fluorescence of these SBPs in response to exposure to various sugars, we found that five of the eight proteins examined bind to sugars. We could not identify the ligands of the SBPs TM0460, TM1150, and TM1199. The ligands for the archaeal SBPs are TM0031 (BglE), the β-glucosides cellobiose and laminaribiose; TM0071 (XloE), xylobiose and xylotriose; TM0300 (GloE), large glucose oligosaccharides represented by xyloglucans; TM1223 (ManE), β-1,4-mannobiose; and TM1226 (ManD), β-1,4-mannobiose, β-1,4-mannotriose, β-1,4-mannotetraose, β-1,4-galactosyl mannobiose, and cellobiose. For comparison, seven bacterial putative sugar-binding proteins were examined and ligands for three (TM0595, TM0810, and TM1855) were not identified. The ligands for these bacterial SBPs are TM0114 (XylE), xylose; TM0418 (InoE), myo-inositol; TM0432 (AguE), α-1,4-digalactouronic acid; and TM0958 (RbsB), ribose. We found that T. maritima does not grow on several complex polypeptide mixtures as sole sources of carbon and nitrogen, so it is unlikely that these archaeal ABC transporters are used primarily for oligopeptide transport. Since these SBPs bind oligosaccharides with micromolar to nanomolar affinities, we propose that they are used primarily for oligosaccharide transport.
THE EFFECT OF HUMAN ENDOTHELIAL CELL‐DERIVED PROTEOGLYCANS ON HUMAN SMOOTH MUSCLE CELL GROWTH

Extracellular proteoglycans (PGs) purified from cultured human arterial endothelial cells were tested for their effects on the proliferation of human vascular smooth muscle cells (VSMC). Fractions containing perlecan, the basement membrane heparan sulphate (HS) PG, the large chondrotin sulphate (CS) proteoglycan from connective tissue and other immunoreactive CS did not inhibit the proliferation of human VSMC. Native endothelial extracellular matrix, which was shown to contain the same PGs, demonstrated a pronounced stimulatory effect on the proliferation of human VSMCs. This stimulatory effect was not removed by pre‐incubation of the matrix with 1M NaCl, heparin, platelet extract or plasmin. These experiments demonstrate that PGs produced by human arterial endothelial cells do not inhibit the proliferation of VSMC. These data do not support the hypothesis that human endothelial cells, in vivo control the activation or proliferation of VSMCs directly by the secretion of a non‐proliferative molecule. Instead they support the hypothesis that the endothelial cells counteract intimal hyperplasia of VSMC indirectly by providing a barrier from activating factors in the plasma.
Hemolytic disease of the newborn

Hemolytic disease of the newborn (HDN) used to be a major cause of fetal loss and death among newborn babies. The first description of HDN is thought to be in 1609 by a French midwife who delivered twins—one baby was swollen and died soon after birth, the other baby developed jaundice and died several days later. For the next 300 years, many similar cases were described in which newborns failed to survive.
The global rise and impact of supermarkets: an international perspective

A ‘supermarket revolution’ has occurred in developing countries in the past two decades. We focus on three specific issues that reflect the impact of this revolution, particularly in Asia: continuity in transformation, innovation in transformation, and unique development strategies. First, the record shows that the rapid growth observed in the early 2000s in China, Indonesia, Malaysia, and Thailand has continued, and the ‘newcomers’ — India and Vietnam — have grown even faster. Although foreign direct investment has been important, the roles of domestic conglomerates and even state investment have been significant and unique. Second, Asia’s supermarket revolution has exhibited unique pathways of retail diffusion and procurement system change. There has been ‘precocious’ penetration of rural towns by rural supermarkets and rural business hubs, emergence of penetration of fresh produce retail that took much longer to initiate in other regions, and emergence of Asian retail developing-country multinational chains. In procurement, a symbiosis between modern retail and the emerging and consolidating modern food processing and logistics sectors has arisen. Third, several approaches are being tried to link small farmers to supermarkets. Some are unique to Asia, for example assembling into a ‘hub’ or ‘platform’ or ‘park’ the various companies and services that link farmers to modern markets. Other approaches relatively new to Asia are found elsewhere, especially in Latin America, including ‘bringing modern markets to farmers’ by establishing collection centres and multi-pronged collection cum service provision arrangements, and forming market cooperatives and farmer companies to help small farmers access supermarkets.
Bank‐company interactions and relationships

Focuses on the relationships and interactions between banks and corporate clients. Explores the possibility of approaching the bank‐company relationship from a different angle. Today banks are facing more aggressive competition and unlimited opportunities. It has become of paramount importance for banks to restructure the relationships with their corporate clients. Our theoretical framework can be traced back to two major theoretical models from outside the bank marketing literature, i.e. the Interaction Approach and the New Concept of Marketing. Empirical data were collected by means of questionnaires. A total of 300 questionnaires were mailed to a random choice of different companies in Sweden. Responses were received from 179 companies (60 per cent). Identifies a large number of factors which influence the interactive relationship between banks and companies.
MAPPING INTERNATIONAL FINANCIAL REPORTING STANDARDS CONVERGENCE ON FINANCIAL STATEMENTS (A COMPARATIVE STUDY BETWEEN UNILEVER AT UNITED KINGDOM AND INDONESIA)

IFRS convergence came in response to the need for relevant and comparable accounting information. IFRS convergence in the EU has started since 2005. While in Indonesia have been fully adopted IFRS from 2012. By doing convergence, then the previous financial statements presented on a GAAP basis will be amended. This study aimed to answer questions such as: what does the complexity of the load of works to be done by a company that has not been fully adopted IFRS; identify the impact of the convergence of IFRS on accounting policies and information and disclosures in the notes to the financial statements of the companies; and what is the proposed mapping strategy that could assist the companies to do their convergence action. The research was conducted by the comparative method of qualitative analysis through case studies on two companies, Unilever Group in the UK and PT.Unilever Indonesia Tbk in Indonesia. The data used are secondary data from the companies’ annual financial statements in 2011. Analysis of the financial statements of the company made toward the 12 IFRS, 26 IAS and 26 PSAK. Refer to 12 IFRS, 26 IAS ,and 26 PSAK analyzed the results showed that the load of works of company (PT. Unilever Indonesia Tbk) that will be full convergence with IFRS is quite complex because of the number of standards to be adopted and the nature of the regulatory principle-based so it requires more judgment and disclosures in the notes to the financial statements. Disclosures made in the notes to the financial statements are more detail because of the use of judgment in financial reporting. The impact of IFRS convergence is significantly seen in the concept of measuring the elements of financial statements in which the fair value is more widely used. Disclosure of items in financial statements is more detail due to the using of judgment in financial reporting. Understanding and evaluating toward new adopted standards and developing a robust accounting policies and procedures followed by gradual adoption of standards is one of mapping strategy that could assist the companies in doing their convergence action.
Infiltration of tumor‐reactive transforming growth factor‐beta insensitive CD8+ T cells into the tumor parenchyma is associated with apoptosis and rejection of tumor cells

TGF‐β is a potent immunosuppressant. High levels of TGF‐β produced by cancer cells have a negative inhibition effect on surrounding host immune cells and leads to evasion of the host immune surveillance and tumor progression. In the present study, we report a distinct ability of tumor reactive, TGF‐β‐insensitive CD8+ T cells to infiltrate into established tumors, secrete relevant cytokines, and induce apoptosis of tumor cells.
Severe digital abnormalities in a patient heterozygous for both a novel missense mutation in HOXD13 and a polyalanine tract expansion in HOXA13

Hox genes encode a highly conserved family of transcription factors with fundamental roles in body patterning during embryogenesis.1 Studies in mouse and chick have shown that the 5‘ HoxD and HoxA genes are critical for vertebrate limb and urogenital tract development.2 In humans, mutations in HOXD13 and HOXA13 cause the rare dominantly inherited limb malformation syndromes synpolydactyly (SPD, MIM 186000) and hand-foot-genital syndrome (HFGS, MIM 140000), respectively. SPD is characterised by syndactyly between the third and fourth fingers and between the fourth and fifth toes, with variable digit duplication in the syndactylous web. Most cases result from expansions of a polyalanine tract in the N-terminal region of HOXD13 3–6 but frameshifting deletions have been identified in three families with an atypical foot phenotype.7,8 HFGS is characterised by short thumbs and halluces, hypospadias in males, Mullerian duct fusion defects in females, and urinary tract malformations in both sexes. Most cases result from nonsense mutations in HOXA13 , but two polyalanine tract expansions and one missense mutation have also been described.9–11 Here we report two Belgian families, one with the first missense mutation to be identified in HOXD13 and the other with only the third polyalanine tract expansion to be identified in HOXA13. Remarkably, intermarriage between the two families has resulted in a girl heterozygous for both mutations, the first human HOXD13 / HOXA13 double heterozygote to be reported. Her digital abnormalities are strikingly more severe than those in carriers of each individual mutation, suggesting that the two mutations act synergistically. ### The proband The proband (fig 1) was born with severe bilateral hand abnormalities (fig 2A-F). She had complete cutaneous syndactyly between the third and fourth fingers, duplication of the distal and proximal phalanges of the fourth fingers, and a rudimentary extra central metacarpal. In addition, both …
Automatic Segmentation of Composition in Carnatic Music Using Time-Frequency CFCC Templates

The Pallavi in a composition in Carnatic music is akin to the chorus or refrain in Western music albeit with a key difference; the Pallavi (or part of it) can be rendered with a number of variations in melody, without any change in the lyrics, and is repeated after each segment of a composition. The objective of this paper is to automatically segment a composition using a partial pallavi query as the template. Cent filterbank [7] based energies and slope features were extracted for both the query and the entire composition. A sliding window of the query duration was used, and the correlation between the mean normalised t-f template and the composition segment within the sliding window was computed. The locations of maximum correlations correspond to Pallavi repetitions. We were able to segment 66% of the compositions accurately. Failures were primarily due to large melodic variations in the repetitions.
Planung und Simulation von Patchimplantaten zur intrakardialen Korrektur angeborener Herzfehler

Kurzfassung. Chirurgische Korrekturen durch Rastelli-artige Operationen bei angeborenen Herzfehlern wie dem Double Outlet Right Ventricle (DORV) oder einer Transposition der großen Arterien (TGA) erfordern eine möglichst genaue Kenntnis der Anatomie des Herzen. Bei diesem Eingriff werden Fehlursprünge der großen Gefäße korrigiert, in dem mit Hilfe eines Patches eine tunnelartige Verbindung geschaffen wird, um so das Blut des linken Ventrikels in die Aorta zu leiten und gleichzeitig den Ventrikelseptumdefekt (VSD) zu verschließen. Die Planung des Patches muss unter Berücksichtigung der Anatomie erfolgen, um die Funktion nicht zu gefährden. So darf durch den Tunnel weder die Trikuspidalklappe noch der rechtsventrikuläre Ausflusstrakt behindert werden. Zur genaueren Visualisierung der Anatomie und zur Planung des Tunnels wurde daher eine Software entwickelt. Mit dieser ist es möglich, den Tunnel innerhalb des Herzens vom linken Ventrikel zum Gefäßursprung durch den VSD dreidimensional zu planen, interaktiv zu verschieben und sich abschließend einen zweidimensionalen Schnittplan zur Konstruktion des Tunnelpatches zu erstellen. Auf diese Weise können Prozeduren bezüglich ihrer technischen Machbarkeit präoperativ evaluiert werden.
A checklist for cerebral aneurysm embolization complications

Complications during cerebral aneurysm embolization continue to occur even at high volume experienced centers. Such situations are unexpected, complex and can have devastating consequences. Individual anecdotal experience offers limited guidance. This literature review of the two most serious neuroendovascular procedural complications—namely, aneurysm perforation and thromboemboli—aims to propose a role based checklist. Having a premeditated plan helps team members remain calm and function more effectively when a procedural complication occurs, with the ultimate goal of minimizing patient harm.
Causal Relevancy Approaches to Improve the Students' Prediction Performance in an e-Learning Environment

In this work, four different causal relevancy (CR) approaches are implemented within the inference engine of the fuzzy inductive reasoning (FIR) methodology. The idea behind CR is to quantify how much influence each system feature has, on the forecasting of the output. This paper presents and discusses the FIR inference engine, and describes how it can be enhanced using the causal relevancy methods proposed in this study. The first two CR methods compute the relevancy of each feature by means of the quality of the optimal mask, obtained in the qualitative model identification step of the FIR methodology. The last two CR methods are based on the prediction error of a validation data set, not used in the model identification process. The CR approaches presented in the paper are applied to a real e-learning course with the goal of improve studentspsila behavior predictions. The experiments carried out with the available data indicate that lower prediction errors are obtained using the CR approaches when compared with the results obtained by the classical FIR inference engine. The new approaches help to improve the understanding of the educative process by describing how much influence each system feature has on the output.