Miracle-dz/UniFAR-FTUs huggingface dataset:
Flockhart, Gordon M. H. and Cranch, Geoffrey A. and Kirkendall, Clay K. (2007) Rapid characterization of the ultraviolet induced fiber Bragg grating complex coupling coefficient as a function of irradiance and exposure

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Effect of dietary amino acid content on canine learning and behaviour

Val developed the first puppy socialisation classes in South Yorkshire, went on to found the charity, Support Dogs, and is well known for her work with assistance dogs – especially their training for people with epilepsy and other complex medical conditions. She has many years of experience in rehabilitating problem dogs and horses, has written a number of booklets, and heads a behaviour practice in the north of England.
SIMULATING LIQUID SOUNDS

Liquid simulations have gained great popularity in recent years due to their visual appeal and the prohibitive cost and di culty of simulating many scenarios involving water. In a recent paper by Greenwood and House [3], they suggest that the addition of bubbles creates more compelling and realistic imagery. Although the quality of graphical simulations is important in providing realism, recent work in audio simulation has shown that the addition of audio can provide further realism to physical simulations. The work on O'Brien [10] and then Raghuvanshi [11] has show promise for rigid body sound synthesis; however, there is no viable simulation method for liquid sounds in physical simulation. Although the parametric model proposed by van den Doel, et al. [12] provides the user with the ability to create audibly realistic liquid sounds, the average user in incapable of estimating the size, frequency and energy of bubbles created in a standard physical situation (pouring, splashing, solid-liquid interactions, etc.). To that end, if a physically motivated process (most likely a uid solver) can be used to generate the distribution of bubbles created by a physical scenario, the user can be absolved of the responsibility of knowing the about the bubbles created in the process and can simply set up a physical scenario and enjoy the resulting sounds.
First detection of a diamagnetic cavity at comet 67P/Churyumov-Gerasimenko

Context: The Rosetta magnetometer RPC-MAG has been exploring the plasma environment of comet 67P/Churyumov-Gerasimenko since August 2014. The first months were dominated by low-frequency waves which evolved into more complex features. However, at the end of July 2015, close to perihelion, the magnetometer detected a region that did not contain any magnetic field at all. Aims: These signatures match the appearance of a diamagnetic cavity as was observed at comet 1P/Halley in 1986. The cavity here is more extended than previously predicted by models and features unusual magnetic field configurations, which need to be explained Methods: The onboard magnetometer data were analyzed in detail and used to estimate the outgassing rate. A minimum variance analysis was used to determine boundary normals. Results. Our analysis of the data acquired by the Rosetta Plasma Consortium instrumentation confirms the existence of a diamagnetic cavity. The size is larger than predicted by simulations, however. One possible explanation are instabilities that are propagating along the cavity boundary and possibly a low magnetic pressure in the solar wind. This conclusion is supported by a change in sign of the Sun-pointing component of the magnetic field. Evidence also indicates that the cavity boundary is moving with variable velocities ranging from 230−500 m/s.
MANIFESTATIONS OF ACUTE ATYPICAL ANTIPSYCHOTICS POISONINGS IN ADULTS ISPITIVANJE KLINIČKIH MANIFESTACIJA AKUTNIH TROVANJA NETIPIČNIM ANTIPSIHOTICIMA KOD ODRASLIH

In the recent years atypical antipsychotics (AAP) become first-line therapy in the treatment of schizophrenia and other psychiatric disorders and the frequency of poisonings with these agents increases. As the theme becomes actual in the last years, a research of the clinical manifestations of acute atypical antipsychotics poisonings in adults admitted in the Clinic of Toxicology UMHATEM „N. I. Pirogov”, Sofia, Bulgaria was conducted. According to literature date the most serious toxicity in overdose with AAP involves effects of the central nervous system and cardiovascular effects, as well as antimuscarinic effects (1, 2, 3, 4, 5).
Globalisation and the State

This essay suggests that those who want to install a "transnational democracy" in the wake of the nation state allegedly having been bypassed by globalisation simply misunderstand what the internationalisation of the state really is all about. Not only is the world still very much composed of states, but insofar as there is any effective democracy at all in relation to the power of capitalists and bureaucrats, it is still embedded in political structures which are national or subnational in scope. Those who advance the nebulous case for an "international civil society" to match the 'nebuleuse' that is global capitalist governance usually fail to appreciate that capitalism has not escaped the state but rather that the state has, as always, been a fundamental constitutive element in the very process of extension of capitalism in our time.
Invited Review Annonaceous Acetogenins: Recent Progress

The Annonaceous acetogenins are promising new antitumor and pesticidal agents that are found only in the plant family Annonaceae. Chemically, they are derivatives of long-chain fatty acids. Biologically, they exhibit their potent bioactivities through depletion of ATP levels via inhibiting complex I of mitochondria and inhibiting the NADH oxidase of plasma membranes of tumor cells. Thus, they thwart ATP-driven resistance mechanisms. This review presents the progress made in the chemistry, biology, and development of these compounds since December 1995.
Science and international nature conservation

International nature conservation programs were originally driven by field biologists. As environment has assumed increasing prominence on the international political agenda, the role of biologists has been marginalised. International programs now have ambitious targets set by politicians and aspire to save the world.There is a need to balance these global environmental initiatives with a set of shorter-term practical actions to maximise biodiversity conservation. Biological scientists can cooperate with other natural resource specialists and social scientists in defining more targeted cost-effective nature conservation programs. A case is made for the Prince Bernhard Chair at the University of UTRECHT to focus on this interface between science and conservation practices.
Structure and Function of Stefin B Oligomers – Important Role in Amyloidogenesis

Many functional proteins act as oligomers. Oligomerization is a well-controlled and regulated process. Those proteins cannot adopt their physiological functions without oligomerization, while the protein misfolding and subsequent unphysiological oligomerization influence the primary protein functions and produce a “gain in toxic function” as the prefibrillar oligomers are toxic for the cells. Misfolding, oligomerization and aggregation are the reasons for the so called conformational diseases. Several of them are neurodegenerative, but some also affect other vital organs. The accumulation of intracellular protein aggregates (various inclusions) and of extracellular protein deposits cause severe cellular degeneration, such as neurodegen‐ eration of affected neurons. Different proteins form rather similar but not identical fibrillar structures, all showing cross-β-structure, where continuous β-sheets run perpendicular to the long axis of the fibrils.
Cultivo do Tomate Cereja sob Sistema Hidropônico: Influência do Turno de Rega

O cultivo hidropônico em tomate cereja é uma técnica que vem cada vez mais se expandindo no país. São necessárias várias metodologias para que se obtenham bons resultados de produtividade. O objetivo do presente trabalho foi conhecer e debater através de revisão bibliográfica como o turno de rega pode ser utilizado como ferramenta para melhorias de sistemas hidropônicos, especificamente, para cultura do tomate cereja, relatando as vantagens e desvantagens que o sistema hidropônico pode agregar comparado ao sistema de cultivo convencional, além de abordar aspectos referentes à cultura do tomate cereja, como: exigências climáticas e comercialização. A solução nutritiva adotada em sistemas de hidroponia considera os elementos que são necessários para o desenvolvimento da planta, vale ressaltar que o tomateiro é uma planta altamente exigente em nutrientes. O turno de rega pode ser empregado para redução de gastos com energia elétrica, menor utilização de nutrientes, bem como diminuir a quantidade de água utilizada para circulação no sistema. A hidroponia se apresenta como técnica de cultivo muito utilizada para diversas culturas, amenizando os problemas fitossanitários, melhorando o controle dos aspectos nutricionais, redução do ciclo da cultura e obtenção de olerícolas de alta qualidade com alto padrão comercial. A adequação do turno de rega, em tomate cereja, é economicamente viável e sustentável ao produtor, diminuindo gastos e otimizando a produção. Palavras-chave: Solanum lycopersicum var. cerasiforme. Tomate. Hidroponia.AbstractThe hydroponic cultivation in cherry tomatoes is a technique that has been increasingly expanding in the country. Several methodologies are required to achieve good productivity results. The purpose of the present work was to know and debate through a bibliographical review how the irrigation shift can be used as a tool for improvements of hydroponic systems, specifically for cherry tomato crop, reporting the advantages and disadvantages that the hydroponic system can add compared to the conventional cultivation system, besides addressing aspects related to the cherry tomato crop as climatic requirements and commercialization. The nutrient solution, adopted in hydroponic systems considers the elements that are necessary for the plant development, it is worth mentioning that tomato is a plant highly demanding in nutrients. The irrigation shift can be used to reduce expenses with electricity, less use of nutrients as well as decrease the amount of water used for circulation in the system. Hydroponics is presented as a widely used cropping technique for many crops, mitigating phytosanitary problems, improving the control of nutritional aspects, reducing the crop cycle and obtaining high quality olericultural plants with high commercial standards. The suitability of the irrigation shift in cherry tomatoes is economically viable and sustainable to the producer, reducing expenses and optimizing production.Keywords: Solanum lycopersicum var. cerasiforme. Tomato. Hydroponics
VEGETATIVE COVERS FOR SEDIMENT CONTROL AND PHOSPHORUS SEQUESTRATION FROM DAIRY WASTE APPLICATION FIELDS

Excessive phosphorus (P) in runoff contributes to eutrophication of fresh water bodies. Studies have shown that manure and effluent from animal feeding operations (AFOs) applied to waste application fields (WAFs) have contributed to excess P in segments of the North Bosque River in north central Texas. There is a growing need for environmentally sound, economically viable, and easily implemented best management practices (BMPs) to control such pollution. Vegetative buffer strips offer a potential solution for reducing runoff P from WAFs by extracting it from soil and reducing sediment P delivery to streams by decreasing runoff and soil erosion. In a field study, ten plots (5 m × 5 m) were assigned to five replicated treatments, namely control (bare ground), cool-season grass, warm-season forb, warm-season grass, and warm-season legume, to assess their efficacy for runoff sediment control and P sequestration. Plots were established on a coastal Bermuda grass WAF that received dairy lagoon effluent. Runoff collection systems were installed on the upstream and downstream margins of each plot. Natural rainfall runoff samples were collected and analyzed for total P, dissolve reactive P, and total suspended solids (TSS). Additionally, the total mass of runoff collected from each subplot was estimated. Results show that the warm-season forb and warm-season grass covers were the most effective treatments for reduction of runoff P, primarily due to reduced sediment content in the runoff compared to other treatments.
AFIT/GIR/LAS/99D-1 IMPLEMENTATION OF SPEECH RECOGNITION SOFTWARE FOR TEXT PROCESSING: AN EXPLORATORY ANALYSIS THESIS

In recent years, information technology has advanced at an incredible pace. One new technology that has recently become available to the average computer user is speech recognition software for text processing. The rationale behind implementing such new technologies is often to gain productivity improvements associated with the substitution of machinery for labor. However, the literature shows little direct evidence of a positive relationship between information technology investment and subsequent productivity benefits. This thesis reports on the examination into the productivity implications of implementing speech recognition software in a text-processing environment. More specifically, research was conducted to compare text processing speeds and error rates using speech recognition software versus the keyboard and mouse. Of interest was the time required to input and proofread text processing tasks as well as the number of errors generated using both methods of text input. The empirical data offer somewhat mixed results. While users initially entered text faster using speech recognition software (p < .05), they generated more errors and consequently performed proofreading and error corrections slower using speech. These results suggest that, in terms of accurate text processing, speech recognition software is still not a practical alternative to the keyboard. Therefore, implementation of speech recognition software is unlikely to result in any gains in productivity that would serve to justify its cost.
Identification of mechano-sensitive C fibre sensitisation and contribution to nerve injury induced mechanical hyperalgesia Author

250 words Background: C fibre hyperexcitability is fundamental to chronic pain development in humans and rodents therefore peripheral sensory neuronal sensitisation plays a role in the development of mechanical hyperalgesia. However, the axonal properties and underlying mechanisms that are associated to these chronic pain states still requires investigation. Methods: Teased fibre electrophysiology of the saphenous nerve was used to identify C fibres in naïve and nerve injured rats. C fibres were identified using electrical stimulation which further provided conduction velocity slowing profiles. Further, in these nerve filaments evoked responses to mechanical stimuli were recorded. Vehicle or galanin were applied directly to the saphenous nerve trunk prior to stimulation. Results: Increased levels of mechanically evoked activity in mechano-sensitive C fibres was associated to reduced conduction failure, enhanced conduction velocity latency recovery and reduced conduction velocity slowing. Mechanical hyperalgesia developed in nerve injured animals in which mechano-sensitive C fibres demonstrated increased mechanically evoked responses and reduced rate of adaptation. Mechano-sensitive C fibres in nerve injured animals had reduced levels of conduction velocity slowing, enhanced rate of conduction velocity recovery and reduced firing frequency failure versus naïve animals; all hallmarks of enhanced sensory neuronal excitability. Directly applying the anti-nociceptive agent galanin to the saphenous nerve trunk in naive animals led to increased conduction failure, reduced latency recovery rate and increased levels of conduction velocity slowing. Discussion: Nerve injury induced enhanced neural responses to mechanical stimulation are associated to defined parameters setout by conduction velocity slowing, mediated via axonal processing. Application of galanin inhibits axonal excitability.
Gersten's conjecture and the homology of schemes

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Moraine-dammed lake distribution and outburst flood risk in the Chinese Himalaya

Abstract To better understand the risk of disasters due to glacial lake outburst floods (GLOFs), we synthetically analyze the spatial distribution and evolution of moraine-dammed lakes and potentially dangerous glacial lakes (PDGLs) in the Chinese Himalaya. Our county-based assessment of GLOF disaster risk combines PDGL outburst hazard, regional exposure, vulnerability of exposed elements and adaptation capability (risk management) using the analytic hierarchy process. We synthetically analyze the disaster risk using the weighted comprehensive method. Remote-sensing data show there are 329 moraine-dammed lakes (>0.02 km2; total area 125.43 km2) in the Chinese Himalaya, of which 116 (total area 49.49 km2) are identified as PDGLs. The zones at highest risk of GLOF disaster are mainly located in Nyalam, Tingri, Dinggyê, Lhozhag, Kangmar and Zhongba, in the mid-eastern Himalaya. Lowest-risk zones are located in the eastern Himalaya. On the county scale, Lhozhag and Lhunze have the highest hazard degrees and exposure, while Zhongba and Zando have the highest degree of vulnerability and lowest adaptation capacity. Our regionalization results for GLOF disaster risk are consistent with the distribution of historical disaster sites across the Chinese Himalaya.
Award Number: W81XWH-16-1-0005 TITLE: Lymph Node Metastases Optical Molecular Diagnostic and Radiation Therapy

Radiation therapy produces Cherenkov optical emission in tissue, and this light can be utilized to activate molecular probes. The feasibility of sensing luminescence from a tissue molecular oxygen sensor from within a human body phantom was examined using the geometry of the axillary lymph node region. Detection of regions down to 30-mm deep was feasible with submillimeter spatial resolution with the total quantity of the phosphorescent sensor PtG4 near 1 nanomole. Radiation sheet scanning in an epi-illumination geometry provided optimal coverage, and maximum intensity projection images provided illustration of the concept. This work provides the preliminary information needed to attempt this type of imaging in vivo. © 2018 Society of Photo-Optical Instrumentation Engineers (SPIE) [DOI: 10.1117/1.JBO. 23.XX. XXXXXX]
Energy Management and Economic Operation Optimization of Microgrid under Uncertainty

Microgrid provides an effective means to promote renewable energy utilization via deploying multiple distributed generations (DGs) with energy storage systems (ESSs), loads, control devices and protect devices, which can operate in either islanded mode or grid-connected mode. In order to coordinate the output of different DGs and realize the potential of renewable energy, energy management and economic dispatch of micro‐ grid is needed. Both distributed energy resources (DERs) and user loads in microgrid have uncertainty characteristics; so the randomness of the wind speed and solar radiation intensity are modeled by interval mathematics and the interval output of the wind turbine and photovoltaic (PV) generation system are obtained. Then, a microgrid economic optimization model based on interval optimization method is proposed. Next, com‐ bined with the time-of-use characteristic, issue of the power exchange with the external grid has been considered. Finally, Considering the effect of ESS, this chapter discusses the impacts of uncertainty of renewable energy power and load power on optimization results, as well as the effects of the degree of load uncertainty or load fluctuation on scheduling results. The results verify the robustness and effectiveness of the proposed method in dealing with uncertainty optimization problem of microgrid.
Improving Differentiable Neural Computers Through Memory Masking, De-allocation, and Link Distribution Sharpness Control

The Differentiable Neural Computer (DNC) can learn algorithmic and question answering tasks. An analysis of its internal activation patterns reveals three problems: Most importantly, the lack of key-value separation makes the address distribution resulting from content-based look-up noisy and flat, since the value influences the score calculation, although only the key should. Second, DNC's de-allocation of memory results in aliasing, which is a problem for content-based look-up. Thirdly, chaining memory reads with the temporal linkage matrix exponentially degrades the quality of the address distribution. Our proposed fixes of these problems yield improved performance on arithmetic tasks, and also improve the mean error rate on the bAbI question answering dataset by 43%.
Genomic and Expression Profiling of Benign and Malignant Nerve Sheath Tumors in Neurofibromatosis Patients

Abstract : The goal of the study is to identify genes and pathways that are associated with the progression of neurofibroma to MPNST, and to identify potential therapeutic targets for MPNSTs. In the past year, to the existing 80 gene array data, we added an additional 23 tumor samples making to a total of 103 gene arrays. The analyses included 38 cases diagnosed as MPNSTs and 24 cases of neurofibromas. Our initial hierarchical clustering showed high degree of variability of MPNST cases. A centralized review of histology was performed; of the 38 cases with the original diagnosis as MPNST, 14 cases were reclassified. In addition all MPNST and SS cases underwent RT-PCR for t(X;18). The misdiagnosed tumor cases were removed from the study, and a subsequent analysis and hierarchical clustering showed a much more interpretable result. The clustering of the nerve sheath tumors revealed a distinct expression signature for majority of benign and malignant tumor types. A subset of MPNSTs clustered along with SS. Using a large tissue microarray (TMA) with about 200 nerve sheath tumors we have identified a novel diagnostic marker TLE1 to distinguish SS from other sarcomas. The signaling pathways TGFB, JAK- STAT, MET were identified as being potentially involved in the malignant transformation. Array comparative genomic hybridization was performed on 28 tumor cases and copy number changes were assessed for each case.