Miracle-dz/UniFAR-FTUs huggingface dataset:
Utilização de técnicas de mineração de dados educacionais para predição de desempenho de alunos de EaD em ambientes virtuais de aprendizagem

This work reports application of data mining techniques in an virtual learning environment (AVA) that uses Moodle like distance learning courses platform. Educational data mining produces methods and techniques that seek patterns discovery for providing usable insights on prediction of teaching and learning processes. Experiment uses real data from a historical basis, which contains thirteen classes of undergraduate courses, being part of a study that seeks to improve distance learning process of Federal University of Rio Grande do Norte. Resumo. Este trabalho relata a aplicação de técnicas de mineração de dados em ambiente virtual de aprendizagem (AVA) que utiliza o Moodle como plataforma para realização de cursos de graduação à distância. A mineração de dados educacionais produz métodos e técnicas que objetivam a descoberta de padrões que forneçam conhecimentos utilizáveis na predição dos processos de ensino e aprendizagem. O experimento utiliza dados reais de uma base histórica contendo treze turmas de cursos de graduação, sendo parte de um estudo que visa melhorar o processo de ensino à distância da Universidade Federal do Rio Grande do Norte (UFRN). 1. Introdução Existem diversas modalidades de Ensino na área da Educação, sendo uma delas a Educação à Distância (EaD), que se caracteriza por sua prática pedagógica diferenciada no processo de ensino e aprendizagem. Tal modalidade de ensino acontece por meio da utilização de tecnologias da informação e comunicação em seus mais distintos graus DOI: 10.5753/cbie.sbie. 2017.1527 1527 Anais do XXVIII Simpósio Brasileiro de Informática na Educação (SBIE 2017) VI Congresso Brasileiro de Informática na Educação (CBIE 2017)
Overview and Future Opportunities of Sentiment Analysis Approaches for Big Data

The ability to exploit public sentiment in social media is increasingly considered as an important tool for market understanding, customer segmentation and stock price prediction for strategic marketing planning and manoeuvring. This evolution of technology adoption is energised by the healthy growth in big data framework, which caused applications based on Sentiment Analysis (SA) in big data to become common for businesses. However, scarce works have studied the gaps of SA application in big data. The contribution of this paper is two-fold: (i) this study reviews the state of the art of SA approaches. including sentiment polarity detection, SA features (explicit and implicit), sentiment classification techniques and applications of SA and (ii) this study reviews the suitability of SA approaches for application in the big data frameworks, as well as highlights the gaps and suggests future works that should be explored. SA studies are predicted to be expanded into approaches that utilise scalability, possess high adaptability for source variation, velocity and veracity to maximise value mining for the benefit of the users.
The influence of geological, geochemical, and biogenic habitat heterogeneity on seep biodiversity

Cold seeps are among the most heterogeneous of all continental margin habitats. Abiotic sources of heterogeneity in these systems include local variability in fluid flow, geochemistry, and substrate type, which give rise to different sets of microbial communities, microbial symbiont-bearing foundation species, and associated heterotrophic species. Biogenic habitats created by microbial mats and the symbiotic species including vesicomyid clams, bathymodiolin mussels, and siboglinid tubeworms add an additional layer of complexity to seep habitats. These forms of habitat heterogeneity result in a variety of macrofaunal and meiofaunal communities that respond to changes in structural complexity, habitat geochemistry, nutrient sources, and interspecific interactions in different ways and at different scales. These responses are predicted by a set of theoretical metacommunity models, the most appropriate of which for seep systems appears to be the ‘species sorting’ concept, an extension of niche theory. This concept is demonstrated through predictable patterns of community assembly, succession, and beta-level diversity. These processes are described using a newly developed analytical technique examining the change in the slope of the species accumulation curve with the number of habitats examined. The diversity response to heterogeneity has a consistent form, but quantitatively changes at different seep sites around the world as the types of habitats present and the size-classes of fauna analyzed change. The increase in beta diversity across seep habitat types demonstrates that cold seeps and associated biogenic habitats are significant sources of heterogeneity on continental margins globally.
Inhibit ion o f Inter leukin 8 Attenuates

From the *Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109-0360; the *Section of Oral Pathology, University of Michigan Dental School, Ann Arbor, Michigan 48109-I078; the SDepartment of Pathology, University of Michigan; and the UDepartment of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, Michigan 48109
Insulin Resistance and Body Fat Distribution: Contribution of visceral fat accumulation to the development of insulin resistance and atherosclerosis

Abstract Body fat distribution can be assessed by computed tomography (CT). The ratio of umbilicus was used to classify obese subjects as having visceral fat obesity (VFO) or subcutaneous fat obesity (SFO). Serum triglyceride and total cholesterol levels and plasma glucose area in an oral glucose tolerance test were higher in patients with VFO than in those with SFO. Significant positive correlations were demonstrated between V/S ratio and plasma glucose area, serum triglyceride level, and total cholesterol level as well as systolic or diastolic blood pressure. VFO was more frequently associated with coronary artery disease. Moreover, VFO was more often accompanied by multiple risk factors than was SFO. Steady-state plasma glucose (SSPG) level was significantly higher in patients with VFO than with SFO, suggesting that insulin resistance may be more remarkable in VFO than in SFO. Furthermore, visceral fat accumulation was also associated with these complications even in nonobese subjects. Visceral fat area (VFA) was significantly correlated with fasting plasma glucose, serum triglyceride, and total cholesterol levels. Animal models such as Goto-Kakizaki (GK) rats with ventromedial hypothalamus (VMH) lesions and Otsuka-Long-Evans-Tokushima-Fatty (OLETF) rats were accompanied by visceral fat accumulation and an early stage of aortic atherosclerosis. Aging, sex hormone, genetic, and dietary factors and physical inactivity may induce visceral fat accumulation. Visceral fat is characterized by its high lipogenic activity as well as its accelerated lipolytic activity. High levels of portal free fatty acids (FFAs) may eventually result in an enhancement of hepatic triglyceride synthesis, causing hyperlipidemia. High portal FFA levels would also induce insulin resistance, thereby causing glucose intolerance, hypertension, and finally atherosclerosis. We propose a term, "visceral fat syndrome," as a highly atherogenic state, which includes visceral fat accumulation, glucose intolerance (insulin resistance), hyperlipidemia, and hypertension.
Do Analysts Sacrifice Forecast Accuracy for Informativeness?

Analysts deviate from management guidance to correct for perceived earnings management. Although the deviations reduce forecast accuracy, they improve forecast informativeness, bringing the forecasts closer to the unmanaged earnings and reducing accruals mispricing. An implicit assumption in the literature is that more accurate analyst forecasts (i.e., estimates that are closer to the reported earnings) are better for investors, and that analysts' objective is to forecast the reported (managed) earnings accurately. Our analysis suggests that this is not necessarily the case and that an inaccurate forecast can actually be more informative than an accurate one. Prior studies on analysts' deviations from management guidance focus on analysts' incentives to issue estimates that managers can beat. These studies implicitly assume that analysts side with management against the interests of their clients. Our analysis indicates that analysts could also deviate from management guidance to provide useful valuation information to their clients. This paper was accepted by Mary Barth, accounting.
The design and use of an FM-AM radiotelemetry system for multichannel recording of biological data.

A multichannel telemetry system for EEG recording has been constructed for study of animal or human behavior correlates under natural, unrestrained conditions. To be useful in research of this kind, the transmitted radio signal must be independent of the environment, so that changes in antenna loading and in signal level cause no artifact. Standard IRIG proportional-bandwidth FM subcarrier channels are used. These subcarriers are generated by twin-T oscillators, modulated in turn by the amplified data signals. The FM subcarriers are then linearly summed and impressed upon a crystal-controlled AM transmitter. The system is also relatively insensitive to major shifts in supply voltage. Wherever possible, fabrication was by means of integrated circuits, thus reducing the bulk of the modules.
Oncogenes and angiogenesis: signaling three-dimensional tumor growth.

Three-dimensional tumor growth is dependent on the perpetual recruitment of host blood vessels to the tumor site. This recruitment process (mainly via angiogenesis) is thought to be triggered, at least in part, by the very same set of genetic alterations (activated oncogenes, inactivated/lost tumor suppressor genes) as those responsible for other aspects of malignant transformation (e.g., aberrant mitogenesis, resistance to apoptosis). Potent oncogenes are able to deregulate expression of both angiogenesis stimulators and inhibitors in cancer cells. For example, mutant ras expression is associated with increased production of vascular endothelial growth factor (VEGF) and downregulation of thrombospondin-1 (TSP-1). Upregulation of VEGF and angiogenesis can also be induced by constitutive activation of other oncogenic proteins (e.g., EGFR, Raf, MEK, PI3K) acting at various levels on the Ras signaling pathway. The mode and the magnitude of such proangiogenic influences can be significantly modified by cell type (fibroblastic or epithelial origin), epigenetic factors (hypoxia, changes in cell density), and/or presence of additional genetic lesions (e.g., preceding loss of p16 or p53 tumor suppressor genes). Activated oncogenes (e.g., ras, src, HER-2) induce co-expression of angiogenic properties concomitantly with several highly selectable traits (increased mitogenesis, resistance to apoptosis), a circumstance that may accelerate selection of the angiogenic phenotype at the cell population level. On the other hand oncogene-induced reduction in growth requirements may also endow tumor cells with a diminished (albeit not abrogated) dependence on (close) proximity to blood vessels, i.e., with reduced vascular dependence. Thus, oncogenes can impact several interconnected aspects of cellular growth, survival, and angiogenesis. Experimental evidence suggests that, in principle, many of these properties (including angiogenesis) can be simultaneously suppressed (and tumor stasis or regression induced) by effective use of the specific oncogene antagonists and signal transduction inhibitors.
Do Subject Characteristics Modify the Effects of Particulate Air Pollution on Daily Mortality Among the Elderly?

Objective: Studies have reported associations between mortality and air pollution, but questions subsist on the identification of susceptible subgroups in the population. We studied individual characteristics that modify the relationship between particulate air pollution and mortality among elderly. Method: We examined 527 nonaccidental deaths (197 cardiorespiratory deaths) among the 1469 subjects from the Personnes Agées QUID cohort in Bordeaux between 1988 and 1997. Air pollution was measured as black smoke by urban monitoring background stations. We used a case crossover approach and calculated odds ratio by conditional logistic regression models. Results: We observed associations between the third lag day and cardiorespiratory mortality for an increase of 10 &mgr;g/m3 of black smoke (odds ratio = 1.30, 95% confidence interval: 1.01–1.68). Conclusions: Our results provide insight into factors possibly conferring susceptibility to the acute effect of urban air pollution.
Survey on Bug Triage with Software Data Reduction Techniques

: Bug triage is an essential step in the process of bug fixing. Bug triage is the process of fixing bug whose main objective is to correctly allocate a developer to a new bug further handling. Many software companies spend their most of cost in dealing with these bugs. To decrease the time cost in manual work and to enhance the working of automatic bug triage, two techniques are applied namely text classification and binary classification. In literature various papers address the problem of data reduction for bug triage, i.e., how to reduce the scale and improve the quality of bug data. By combining the instance selection and the feature selection algorithms to simultaneously reduce the data scale and enhance the accuracy of the bug reports in the bug triage. This survey focused on various data reduction technique for bug triage. As per literature, need to develop a effective model for doing data reduction on bug data set which will reduce the scale of the data as well as increase the quality of the data. , by reducing the time and cost.
Polarization-Independent All-Fiber Acousto-Optic Tunable Filter Using Torsional Acoustic Wave

The intrinsic polarization dependence of an all-fiber tunable wavelength filter based on polarization coupling by torsional acoustic wave is eliminated by employing a fiber loop configuration. In the fiber loop, two orthogonal polarizations split from input light propagate the single acousto-optic interaction region in opposite directions before being recombined to produce a polarization-independent filter spectrum. The polarization-dependent loss was estimated to be less than 0.1 and 0.3 dB within passband in bandpass and notch type filters, respectively.
Ventricular fibrillation during anesthetic induction in a child with undiagnosed mitral valve prolapse.

S udden cardiac arrest during anesthesia in apparently healthy children may occur in the absence of anesthetic overdose due to various preexisting conditions that may not be readily clinically apparent. Arrhythmias during anesthesia induction may be caused by factors such as hypoxia, hypercarbia, and stimulation during inadequate anesthesia. When undiagnosed congenital cardiac anomalies, such as mitral valve prolapse, are exacerbated by anesthetic induction, arrhythmias and cardiovascular collapse may result. Ventricular bigeminy, multifocal premature ventricular contractions, and ventricular tachycardia have been reported during anesthesia in a pediatric patient who was subsequently diagnosed with mitral valve prolapse (1). The following is a case of ventricular fibrillation during anesthetic induction in a child with undiagnosed mitral valve prolapse.
Study of molecule variations in human xanthelasma skin based on confocal micro-raman spectroscopy.

Confocal micro-Raman spectroscopy was used to distinguish human xanthelasma skin (HXS) from the human normal skin (HNS). Results showed that intensive Raman peaks at 1,269, 1,336, 1,448, and 1,656 cm(-1) increased obviously. Both 1,269 and 1,656 cm(-1) peaks showed that the proteins in HXS were mostly in the anti-parallel ß sheet conformation. While the intensities of bands at 1,032, 1,087, 1,300, and 1,448 cm(-1) belonged to lipids were enhanced in HXS spectrum compared to those in HNS spectrum. There were main intercellular lipids alkyl chains with minor proteins contribution at 1,087 cm(-1) and phenylalanine at 1,032 cm(-1) . To quantitative analysis of the difference, the ratio of I852/I829 was calculated, which was 1:1.04 ± 0.04 and 1:1.11 ± 0.02 for HNS and HXS (p < 0.01), respectively. The data indicated that some tyrosine residues, which form a hydrogen bond with H2 O prior to aggregation, were captured by strong hydrogen-bond acceptors in the aggregate. The decreased ratio of I852/I829 indicated more hydrophobic in HXS than HNS. Principal component analysis showed a one-to-one relationship between human xanthelasma skin and the corresponding Raman spectra. It could be given useful help for the diagnostication of xanthelasma.
The gene road to royalty – differential expression of hydroxylating genes in the mandibular glands of the honeybee

The advances in honeybee sociogenomics have paved the way for the study of social communication processes at the gene level, in particular the expression of caste‐specific pheromones. The queen honeybee mandibular pheromone provides an excellent model system, in that biosynthesis of the hydroxylating fatty acid caste‐specific pheromone appears to be reduced to a single chemical hydroxylation step of stearic acid. Queens are typified by ω‐1‐hydroxylation, as opposed to the worker‐typical ω‐hydroxylation. We hypothesized that this bifurcation is the consequence of differential expression of caste‐specific genes that code for fatty acid‐hydroxylating enzymes from the cytochrome P450 (CYP) family. Bioinformatics studies disclosed two candidate proteins CYP4AA1 and CYP18A1. We thus investigated the expression of these genes in the mandibular glands of queens, and of queenright (QR) and queenless (QL) workers. The real‐time PCR results revealed that CYP4AA1 (ω‐hydroxylation) was expressed at high levels in both QR and QL workers, whereas in queens its expression was negligible. The expression of CYP18A1 (ω‐1‐hydroxylation), on the other hand, was high in the queen’s glands and negligible in those of QR workers. In QL workers, however, the expression of CYP18A1 was considerably elevated and significantly greater than in QR workers. Three‐dimensional structural models constructed for these enzymes demonstrate differences in the active site between CYP18A1 and CYP4AA1, in line with their differential catalytic specificity. The fact that queen pheromone plasticity can be tracked all the way to gene expression provides a new insight into the process of caste differentiation and the accompanying social communication.
Framework for IP switching over fast ATM cell transport (IPSOFACTO)

This paper describes a method for mapping IP flows to ATM switches. No signaling is necessary to setup a path through ATM switches. Switch controllers run an IP routing protocol and execute IP forwarding. The IPSOFACTO component is responsible for mapping a IP flow to a switched path. Mechanisms for switching both multicast and unicast flows are described.
Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor.

A combination of histological stains has been used to obtain maximum contrast between capillary endothelial cells, fibroblasts, and parenchymal cells in sections of a transplanted C3H mouse mammary tumor. Values of kinetic parameters were estimated by thymidine labeling techniques and autoradiography for each of these three cell populations. The mean thymidine labeling index of carcinoma cells was 35%. Mitotic index, labeling index, and mean grain count per labeled cell decreased with distance of carcinoma cells from a capillary; there was migration of cells from regions of rapid proliferation near blood vessels to regions of slow or non-proliferation near necrosis. The duration of the cell cycle phases was estimated by a labeled mitoses experiment, and computer methods were used to analyze these results. The median cell cycle time was 13 hr, and the growth fraction was estimated from a repeated thymidine labeling experiment to be about 50%. Therefore, the turnover time of the carcinoma cells was about 22 hr. The mean thymidine labeling indices of capillary endothelial cells and fibroblasts were 11.4 and 9.1%, respectively. These cells rarely were recognized in mitosis, and their turnover times were estimated from a repeated labeling experiment. The results were consistent with a turnover time of 50 to 60 hr for endothelial cells and 70 to 80 hr for fibroblasts, with a wide spread in the distribution of intermitotic times. The mean labeling index of capillary endothelial cells remained quite constant between 10 and 40 hr after a single injection of tritiated thymidine; this result implies that capillary endothelial cells are not derived from a faster-proliferating precursor population. Extension of the capillary network in the growing tumor appears to depend mainly on the division of endothelial cells within the capillary walls.
Immunomodulatory function of orally administered thymosin alpha1.

OBJECTIVE To investigate the immunological function of a yeast expression system for thymosin alpha1 (Talpha1). METHODS A constructed Talpha1 yeast expression system was used to investigate the immunological function of orally administered Talpha1. Dried yeast containing three different concentration of Talpha1 was fed to normal Balb/c mice and other Balb/c mice whose immunities were inhibited in advance by cyclophosphamide. Synthesized Talpha1 peptide was used as positive control and dried yeast with empty plasmid was used as negative control. CD4(+) and CD8(+) levels were detected by flow cytometry assay. TNF-alpha, IFN-gamma, IL-2, IL-6 and IL-10 levels were detected by liquid chip. RESULTS In normal Balb/c mice or immune inhibition Balb/c mice, CD8(+) levels were significantly increased. Especially in immune inhibition Balb/c mice, CD8(+) levels in synthesized Talpha1 group (18.77%+/-4.72%), small dose group (13.48%+/-6.17%) and large dose group (22.74%+/-1.09%) were significantly higher than that in empty yeast control group (7.49%+/-2.14%). CONCLUSION Orally administered Talpha1 has its certain immunomodulatory function.
Practical approaches to seeking assent from children.

AIM To describe and evaluate two approaches--a storyboard and a wordsearch--that the authors used with children aged four to 12 years to obtain assent. BACKGROUND The assent process is vital in helping children to understand the elements of a research project and to make a choice of whether or not to participate. However, the methods for obtaining assent are not well documented. DATA SOURCES Two researchers' thematic reviews of the primary researcher's field notes, taken during a study of eating problems during chemotherapy. DISCUSSION The assent process appeared to be an enjoyable, positive experience for many children. They appeared to understand what participation entailed--that it was voluntary and that they had a choice. CONCLUSION When using child-centred techniques, children are aware of what being in a research study will mean to them. IMPLICATIONS FOR PRACTICE Researchers can be confident in gaining assent from children as young as five years.
Strong diffusion approximations for recursive stochastic algorithms

Lai and Robbins (1978) prove strong diffusion approximations for the Robbins-Monro stochastic approximation algorithm. We show that similar strong approximations hold for stochastic algorithms at the level of generality proposed in the monograph of Benveniste, Metivier and Priouret (1990), wherein algorithms with generally discontinous right-hand sides driven by conditionally Markovian data are considered. The relevance of our result is demonstrated on an estimation algorithm with a discontinuous right-hand side which is used in data communication. The technique of adaptive delta modulation used in digital communication is considered.