Miracle-dz/UniFAR-FTUs huggingface dataset:
ANALYTICAL FORMULATION OF THE FRACTURE PATH AND SHEAR RESISTANCE FOR RC BEAMS

Abstract. Shear design for reinforced concrete beams is of significant technological interest. Numerous experimental and numerical work have been developed to predict the shear resistance of reinforced beams. In this work, we consider the fracture path as the equilibrium trajectory resulted from external loads and internal forces; assuming a linear-decreasing cohesive law for concrete bulk, fully-developed fracture process zone size as a material parameter, a perfect plastic bond-slip relation for the interface between steel rebar and concrete, analytical predictions for the crack path and shear resistance for beams with arbitrary geometry, longitudinal and/or shear reinforcement ratio, are derived and validated against available experimental data, the agreement is remarkable.
RESPONSE LETTER TO DR. VISSER

mentia (AD), whereas subjects with multiple impaired cognitive domains MCI (mcd-MCI) who developed dementia all had subcortical vascular dementia (VaD). They concluded that mcd-MCI can be considered to be an early stage of subcortical VaD, although they admitted that these data should be interpreted cautiously because of the possibility of selection bias. It would be useful to compare their findings with those of similar studies performed in other settings. In a population-based study, it was shown that 67% of the subjects with mcd-MCI who developed dementia after a follow-up of 2.6 years had AD, whereas only 12% had VaD. Two longitudinal studies performed in a memory clinic setting with a follow-up of 2 to 3.8 years found that all subjects with mcd-MCI who developed dementia at follow-up had AD. Moreover, 71% to 80% of the cases with AD at follow-up had mcd-MCI at baseline, and only 15% to 29% had a-MCI. Thus, the outcome of subjects with mcd-MCI may be more heterogeneous than appears from the study of Zanetti, and mcd-MCI may also represent early AD. It would be useful if the authors could provide some additional information regarding the classification of MCI used in the study. The definition of absence of impairments in nonmemory domains for subjects with a-MCI is not fully described, such that it is not clear whether subjects with a memory score below 1.5 standard deviations (SDs) and performance on nonmemory tests between 1 SD and 1.5 SDs were classified as having a-MCI or mcdMCI. In addition, it would be interesting to learn how many subjects in the group with mcd-MCI also had memory impairment. Maybe the authors could also comment on some of the findings presented in the tables. First, Table 1 shows that subjects with mcd-MCI have a very high score of 73 on the ‘‘Neuropsychological Inventory’’ (which presumably is the ‘‘Neuropsychiatric Inventory’’). Second, I wondered why the difference between the time needed to complete the Trail Making Test (TMT) B and that needed to complete TMT A (TMT B–A, seconds) in Table 3 is not the same as the difference between the variables TMT B and TMT A in that table.
Healing the Wounds

Sometimes, reading is very boring and it will take long time starting from getting the book and start reading. However, in modern era, you can take the developing technology by utilizing the internet. By internet, you can visit this page and start to search for the book that is needed. Wondering this healing the wounds is the one that you need, you can go for downloading. Have you understood how to get it?
A Review on Digital Watermarking Techniques

Digital watermarking plays very important role in multimedia for several applications such as copyright protection, ownership protection and identification, data authentication, broadcast monitoring etc. The aim of every application is to provide security to the digital information. Digital watermarking is a method of embedding some information with original image in the form of text, image etc. Digital watermarking is a very developing field and widely used in various applications. This paper presents a review on different digital watermarking techniques. The watermarking techniques is mainly two type e.g. spatial domain or frequency domain or on the basis of wavelets.
Exploiting autophagy in multiple myeloma

Multiple myeloma (MM) is a plasma cell cancer characterized by sustained endoplasmic reticulum (ER) stress and unfolded protein response activation in the setting of high rates of immunoglobulin synthesis. Consequently, MM cells rely heavily on protein quality control pathways for survival as evidenced by the clinical efficacy of proteasome inhibitors (PI). Autophagy is an intracellular self-digestion mechanism that plays a role in the ER protein quality control process. Unsurprisingly then, basal levels of autophagy were recently found to confer a survival and drugresistance benefit to MM cells. However, excessive induction of autophagy in MM cells leads to autophagic cell death, highlighting the double-edged nature of autophagy modulation in MM. This review provides an overview of the role that autophagy plays in MM pathogenesis, survival, and drug-resistance. We highlight the potential utility of therapeutically targeting autophagy in MM, focusing on preclinical data of autophagic modulators in combination with alkylators, anthracyclines, PI, and immunomodulatory drugs.
Clustering Web Sessions Using Search Queries

Web session clustering is to discover Web usage patterns from Web log data. Search by queries is often extensively used in a large Web site. Previous research in Web session clustering has used Web session contents, but not search queries. In this study, based on our prior work [10], by considering users’ intentions from search queries, we incorporate queries into Web session clustering by enhancing the weight vectors of sessions with the intentions. The weight vectors are then used in a session similarity calculation during clustering. Therefore, our approach clusters Web sessions not only by their contents, but also by considering users’ intentions from search queries. In our experiments, we apply two approaches on clustering half-month’s Web log from HP. Both approaches use Web session contents, and only one considers users’ intentions from search queries. The experiments showed that the approach considering search queries achieved an 11.6% reduction in entropy over the other approach, measured by distribution of intentions across all clusters.
The Effect of Submucosal Injection of Plasma-Rich Platelets on Blood Inflammatory Markers for Patients with Bimaxillary Protrusion Undergoing Orthodontic Treatment

Objectives The present study aims to reveal the systemic effects of submucosal injection of plasma-rich platelets (PRP) on blood inflammatory markers which was used in an attempt to reduce the retraction time of the upper canine following extraction of upper maxillary premolars for patients with bimaxillary protrusion. Hypothesis No change on comparing the values of blood inflammatory markers before and after submucosal injection of PRP. Methods Eighteen female patients with bimaxillary protusion were selected from patients seeking orthodontic treatment from the College of Dentistry/University of Sulaimai, whose maxillary and mandibular first premolars were decided to be extracted after proper diagnosis. Thirty-three blood markers (twenty hematological and thirteen biochemical markers) were estimated before orthodontic bracketing, 24 hours and 7 days following submucosal injection of PRP (5 cc) to reveal the systematic effect of PRP on blood inflammatory markers that were used in an attempt to reduce the retraction time of the upper canine following extraction of upper maxillary premolars for patients with bimaxillary protrusion. Results The results indicate nonsignificant differences in the values of all blood markers except for gamma GT (GGT), PDWa, serum albumin, serum total protein, and total calcium. Gamma level significantly increased for both test intervals. On the other hand, there was a significant drop in the value of PDWa while for alkaline phosphatase, there was a drop within the first 24 hr of PRP injection while after 7 days the value was significantly increased. On the other hand, there was a drop in the level of serum albumin, while there was an increase in the serum total protein and total calcium. Conclusion Submucosal injection of PRP could lead to systematic alteration of blood parameters including ALK phosphatase, gamma GT, serum albumin, and serum total protein, which may be related to liver function in addition to increase in the level of PDWa and serum calcium. We present evidence that PRP contains and may trigger systemic effect. Thus, further investigation is recommended to follow up the patient for a longer period of time and on a larger sample. This trial is registered with U1111-1221-8829 by Sri Lanka Clinical Trial Registry, SLCTR/2018/040, and No. 64 on 6th August 2018 at the local clinical studies database, College of Dentistry.
Bottom-up and Top-down Face Analysis based on 3D Face Models∗

Many tasks in human-computer-interaction, especially in humanoid robots, require the detection of faces and localization of facial landmarks in images and videos. While the task is considered to be solved for controlled scenarios, most existing approaches are limited to a pose-range of up to half-profile view. Only recently, more holistic approaches [5] have been published able to cope with uncontrolled scenarios. In our approach, we adapt a fast cascaded Wavelet Vector Machine detector [3] from face to facial landmark detection and improve its accuracy by combining it with a 3D face model [4]. As a first application, we use the obtained landmarks with a tree (ERT, [2]) for head pose estimation up to full profile view and show how inaccuracies in the detected landmarks influence performance.
A SYSTEM FOR SIMULATION OF 2D PLANT TISSUE GROWTH AND DEVELOPMENT

Nikolaev S.V. , Penenko A.V. , Belavskaya V.V. , Mjolsness E. , Kolchanov N.A. 1 Institute of Cytology and Genetics, SB RAS, Novosibirsk, 630090, Russia; 2 Institute of Mathematics, SB RAS, Novosibirsk, , 630090, Russia; 3 School of Information and Computer Science, and Institute for Genomics and Bioinformatics, University of California, Irvine, CA, USA * Corresponding author: e-mail: nikolaev@bionet.nsc. ru
The Effects of Electronic Treatment Reminder Cues on Relapse Prevention

Substance use is highly prevalent in the United States, and although treatments designed to reduce substance use have shown promise, relapse rates between 40% and 70% following treatment have been reported in recent studies. Given the high rate and chronicity of relapse following substance abuse treatment, conducting research aimed to develop techniques to lower the risk of relapse following treatment is imperative. A promising option to reduce relapse is to use treatment reminder cues, or cues that are salient features of the treatment environment that can be used to extend the effects of treatment into non-treatment settings. This study investigated the effects of treatment reminder cues on rates of relapse in 50 male and female individuals entering intensive outpatient treatment for substance abuse. It utilized a one-month randomized and controlled design using state-of-the-art electronic handheld computer technology. Participants in the experimental condition were prompted to read and respond to four treatment reminder cues per day in addition to one daily diary survey assessing for a variety of proximal variables related to relapse. All participants were asked to complete assessment questionnaires of relevant variables that may affect relapse at baseline and 1-month follow-up. Chi-square tests were used to determine if adding treatment reminder cues to standard treatment resulted in less relapse relative to standard treatment alone, and whether onset occurred significantly later for those receiving treatment reminder cues. Binary logistic regression analyses investigated the extent to which compliance with treatment reminder cues was associated with relapse. Results indicated that twice as many individuals in the control group relapsed compared to the experimental group, which approached statistical significance. In addition, those in the experimental group relapsed substantially later than did those in the control group. Results indicated no effect of increased compliance on decreased relapse. Overall, this study holds the
Segmentation and Extraction of Human Activity from Still Images

Segmentation of human bodies in images is a challenging task that can facilitate numerous applications, like scene understanding and activity recognition. In order to cope with the highly dimensional pose space, scene complexity, and various human appearances, the majority of existing works require computationally complex training and template matching processes. We propose a bottomup methodology for automatic extraction of human bodies from single images, in the case of almost upright poses in cluttered environments. The position, dimensions, and color of the face are used for the localization of the human body, construction of the models for the upper and lower body according to anthropometric constraints, and estimation of the skin color. Different levels of segmentation granularity are combined to extract the pose with highest potential. The segments that belong to the human body arise through the joint estimation of the foreground and background during the body part search phases, which alleviates the need for exact shape matching. The performance of our algorithm is measured using 40 images (43 persons) from the INRIA person dataset and 163 images from the “lab1” dataset, where the measured accuracies are 89.53% and 97.68%, respectively. Qualitative and quantitative experimental results demonstrate that our methodology outperforms state-of-the-art interactive and hybrid top-down/bottom-up
Study of Thyroid gland function and serum circulating ferritin in Beta-thalassemia Major female patients in Tikrit city Dr .

Beta-thalassemia probably is the most common single gene disorder causing a major genetic health problem in the world. People of Mediterranean, Middle Eastern, African, and Southeast Asian descent are at higher risk of carrying the genes for thalassaemia. Endocrine complications in Thalassaemia Major Patients with multi-transfused Thalassaemia Major develop severe endocrine complications. The aim of the study is to determine the relation between serum circulating ferritin and thyroid gland function in Thalassemic patients. Patients & methods:A cross sectional study was conducted on β-thalassaemia major patients whom attended the thalassaemia center in Tikrit Teaching Hospital (TTH) from beginning of January to the mid of June 2014. Fifty six βthalassemia major female patients aged 10 to 16 were participated in the study. Thirty nine female subjects apparently healthy, with no family history of hereditary blood disease attendants to out-patient pediatric clinic, who were assessed by a pediatrician, all control healthy subjects aged 10 to 16 years. Body weight & height and serum ferritin, serum TSH, T3, & T4 were measured. Results:There was a highly significant increase in serum circulating ferritin concentration in female thalassemic patients as compare with control subjects. Also, there is significant increase in serum Thyroid stimulating hormone (TSH) concentration in female thalassemic patients. However, there is significant reduction in serum T3 and T4 concentrations in female thalassemic patients as compare with female control subjects. Conclusion; Thalassemic female patients had a lower T3 & T4 as compare with normal healthy female control subjects of same age.
Optimal/Fair Taxation and Partial Control: Theory and Evidence

Since Mirrlees (1971), the modern income tax literature typically starts from a welfare maximizing social planner who wants to redistribute earnings on the basis of a distortionary income tax. The underlying reason for using distortionary taxes on earnings is the impossibility of using non-distortionary lump-sum taxes on ability, since the latter is not observed by the social planner. In practice however, tax-bene t schemes are based on much more information than earnings only. Di¤erent theoretical reasons, related to e¢ ciency and equity, have been put forward. In this paper, we want to derive and test an optimal tax-bene t scheme based on several characteristics, which di¤er in terms of the degree of control, i.e., the extent to which a characteristic can be changed by exerting e¤ort. Our theoretical model provides us with a testable relation between the tax rates on the two characteristics and their variance-covariance structure. We then set up an empirical model with a nite number of characteristics which allows us to estimate the tax (or subsidy) rates for the di¤erent characteristics in di¤erent European countries using the 2007 EU-SILC data. Partitioning the set of characteristics into characteristics with zero control -sex, age and disabilityand characteristics with partial controleducation and household composition-, output can be rewritten as a function of two "composite" characteristics, one with partial and one with no control as in the "Akerlof"-case. There is a clear tendency in all countries to compensate more for the "no control"-composite compared to the "partial control"-composite. In addition, when testing the empirical counterpart of the theoretical tax formula in the "Akerlof"-case, we cannot reject that some countries are fair.
Optimal Design of Wind Farm Layout and Control Strategy

1. Abstract Wind energy as one of the alternative energy sources is growing at a rapid rate for its property of renewability and abundancy in the current society. However, high power losses have been witnessed due to the intervention of air flow induced by the upstream wind turbines in the wind farm. Though researches show that the great power losses can be reduced through the optimal design of wind farm layout and control strategy, up to now only separate optimization of wind farm layout or control strategy, i.e., either the wind farm layout optimization with the constant wind turbine operations or the control optimization with the fixed wind turbine positions is reported in literatures. Meanwhile, even though it is convinced that the unrestricted coordinate method is superior to the grid based method for the wind farm layout optimization due to its flexibility to place wind turbines, the comparison between these two wind farm design methods is not made by considering the control optimization. Therefore, this paper aims to fill these research gaps. The combined wind farm layout plus control optimization is conducted in this paper for the first time, and the results of which are compared with the separate wind farm layout optimization and control optimization to demonstrate its effectiveness using both wind farm design methods. The comparative results show that the layout optimization is most inefficient in the optimal wind farm design. The control optimization has most stable performance almost without deviations for repeated calculations, and it is able to attain the best optimization results under 45 degree constant wind direction condition using the unrestricted coordinate method. Even though the combined layout plus control optimization is theoretically superior to the other optimizations which obtains the better results, it is apt to be stuck into the local optima while the global optima cannot be guaranteed with single calculation.
The aix-MARSEC project: an evolutive database of spoken british English

This paper presents the Aix-MARSEC project, an evolutive database of spoken British English. Specific details are given about the grapheme-phoneme conversion from the orthographic transcripts, the optimisation by elision rules of the phonetic transcription, the automatic phoneme-level alignment and automatic higher level treatment (syllables, subsyllabic structure, rhythmic units and MOMEL-INTSINT intonation coding). Integration of users’ contributions will be within the general framework of GNU GPL licensing. Preliminary (pragmatic and prosodic) studies are presented in the final part of the paper.
Large Scale Indium Tin Oxide (ITO) One Dimensional Gratings for Ultrafast Signal Modulation in the Visible

We present a photophysical study on an indium tin oxide (ITO) one dimensional grating, realized using femtosecond micromachining technology, a technology very industrially accessible. The geometries, dimensions and pitch of the various gratings analyzed are obtained by means of direct ablation in a controlled atmosphere of a homogeneous thin layer of ITO deposited on a glass substrate. The pitch has been selected in order to obtain a higher order of the photonic band gap in the visible. By means of ultrafast pump-probe spectroscopy we characterize both the plasmon and inter-band temporal dynamics. We observe a large optical non-linearity of ITO grating in the visible range, where the photonic band gap occurs, when pumped at the surface plasmon resonance in the near infrared (1500 nm). All together we show the possibility of all-optical signal modulation with heavily doped semiconductors in their transparency window with a picosecond response time through the formation of ITO grating structures.
The Agronomic Legacy of Mark A . Carleton

Published in J. Nat. Resour. Life Sci. Educ. 30:120123 (2001). http://www.JNRLSE. org Abbreviations: KSAC, Kansas State Agricultural College; KAES, Kansas Agricultural Experiment Station. M A. CARLETON is known bymembers as the first president of the American Society of Agronomy. However, he also shaped development of the hard red winter wheat (Triticum aestivum L.) and durum wheat (T. turgidumL. var. durum) industries in the USA. The objective of this article is to describe Carletons agronomic legacy: introduction of adapted wheat cultivars, dryland production of wheat, investigations of wheat diseases, and scientific knowledge of wheat. Carleton was the first scientist to recognize the superiority of Turkey hard red winter wheat, which came to dominate the central and southern Great Plains; introduced Kharkof wheat, which became an important cultivar in the central and northern Plains; introduced Crimean wheat, which was a parent of many early improved cultivars; and introduced Kubanka and promoted its production to start the durum wheat industry in the northern Great Plains. He gave the common name to leaf rust (caused by Puccinia recondita f. sp. tritici), determined the physiological relationships among known races of leaf rust and stem rust (caused by P. graminis f. sp. tritici), and was among the first to investigate fungicides for controlling rust diseases. Research directed by Carleton developed suitable methods of dryland farming for the Great Plains and established the relationship between soil moisture and gluten quality of wheat. His publications were a blueprint for development of the U.S. wheat industry, and his book, The Small Grains, became a classic. Members of the American Society of Agronomy should be aware of Carletons achievements because he was considered the most respected agronomist in the USA during his career (Isern, 2000), and he defined the profession in principle and in practice (e.g., Carleton, 19071909, 1915a). It is particularly appropriate to recognize his agronomic legacy because of the controversy that surrounded latter aspects of Carletons life (de Kruif, 1928).