Miracle-dz/UniFAR-FTUs huggingface dataset:
Thermal characterization of power devices using graphene-based film

Due to its atomic structure with sp2 hybrid orbitals and unique electronic properties, graphene has an extraordinarily high thermal conductivity which has been reported to be up to 5000 W/mK. As a consequence, the use of graphene-based materials for thermal management has been subject to substantial attention during recent years in both academia and industry. In this paper, the development of a new type of graphene-based thin film for heat dissipation in power devices is presented. The surface of the developed graphene based film is primarily composed of functionalized graphene oxide, that can be bonded chemically to the device surface and thus minimize the interface thermal resistance caused by surface roughness. A very high in-plane thermal conductivity with a maximum value of 1600 W/mK was detected by laser flash machine regarding to the graphene-based films. To investigate the structure of the graphene-based films, scanning electron microscopy (SEM) and raman spectroscopy were carried out. Finally, LED demonstrators were built to illustrate the thermal performance of graphene-based film and the functional layers. IR camera recorded a 5°C lower temperature of a LED demonstrator with SHT G1000 as the binding layer instead of a commercial thermal conductive adhesive.
Diagramming Aristotle's Nicomachean ethics

L'oeuvre d'Aristote intitulee Ethique a Nicomaque fait traditionnellement partie des programmes d'etudes crees pour les cours d'introduction a la philosophie a l'universite. L'auteur etablit une serie de remarques visant a optimiser l'utilisation de ces ressources philosophiques dans le but d'ameliorer la comprehension et le raisonnement des etudiants.
Process performance measurement system - towards a customer-oriented solution

Purpose – Based on a systematic literature review, requirements on a PPMS are identified in order to derive concrete demands and design features for such a system by using quality function deployment (QFD). The purpose of this paper is to formulate a proposal for design recommendations toward a holistic, customer-oriented Process Performance Measurement System (PPMS). Design/methodology/approach – A literature review is used to identify customer demands and design features that characterize a PPMS. To determine the critical design features of a customer-oriented solution, the QFD method is applied. Findings – The paper confirms that there is currently no published concept for an integrated, holistic PPMS. Therefore it provides a first approach to the formulation of a design recommendation based on the customer requirements and design features. A literature-based weighting facilitates a first identification of critical design features. The identified conditions specify the context which can be regarded as .
Translocation regulation of single - stranded DNA through modified protein nanopores

Wide-type α-hemolysin (WT-αHL) is a promising protein nanopore for nucleic acid analysis in DNA sequencing. In this work, we demonstrated three modified versions of α-HL to compare the translocation behaviour of ssDNA when they pass through the nanopore. Current signal collected from the nanopore mutants during ssDNA translocation through the protein pore provides information about the sequence and structure of the ssDNA molecule. Furthermore, the translocation velocity of ssDNA was remarkably reduced with the modifications of WT-αHL, facilitating high fidelity reads for DNA sequencing.
An extended technology acceptance model for predicting smartphone adoption among young consumers in Greece

This study aims to investigate the effect of variables related to innovation diffusion theory and value consumption theory on young consumers' intentions in the mobile/wireless market. Using the expanded proposed conceptual model, the authors aim to address personal and social issues surrounding smartphone adoption. Based on a quantitative empirical study of 310 respondents, the proposed model suggests that the constructs under examination are linked through established relationships. More specifically, the 'intention to buy a smartphone' is affected by 'perceived usefulness', 'perceived ease of use' and 'materialistic values'. Perceived usefulness (PU) is strongly affected by 'perceived compatibility', which is affected by 'social influence'. 'Materialistic values' are positively influenced by 'social values', which are affected by 'social influence'. Finally, 'perceived ease of use' (PEoU) is influenced by 'perceived behavioural control'. It is argued that the combined use of the value consumption and innovation diffusion theories in the context of the Technology Acceptance Model (TAM) and the Theory of Planned Behaviour (TPB) provides a more integrated theoretical framework to further investigate consumers' behavioural intentions towards technology-related product categories with significant theoretical and managerial implications.
Binding of a pleurotolysin ortholog from Pleurotus eryngii to sphingomyelin and cholesterol-rich membrane domains[S]

A mixture of sphingomyelin (SM) and cholesterol (Chol) exhibits a characteristic lipid raft domain of the cell membranes that provides a platform to which various signal molecules as well as virus and bacterial proteins are recruited. Several proteins capable of specifically binding either SM or Chol have been reported. However, proteins that selectively bind to SM/Chol mixtures are less well characterized. In our screening for proteins specifically binding to SM/Chol liposomes, we identified a novel ortholog of Pleurotus ostreatus, pleurotolysin (Ply)A, from the extract of edible mushroom Pleurotus eryngii, named PlyA2. Enhanced green fluorescent protein (EGFP)-conjugated PlyA2 bound to SM/Chol but not to phosphatidylcholine/Chol liposomes. Cell surface labeling of PlyA2-EGFP was abolished after sphingomyelinase as well as methyl-β-cyclodextrin treatment, removing SM and Chol, respectively, indicating that PlyA2-EGFP specifically binds cell surface SM/Chol rafts. Tryptophan to alanine point mutation of PlyA2 revealed the importance of C-terminal tryptophan residues for SM/Chol binding. Our results indicate that PlyA2-EGFP is a novel protein probe to label SM/Chol lipid domains both in cell and model membranes.
Double-stranded ribonucleic acid killer systems in yeasts

INTRODUCTION . 126 KILLER dsRNAs, MYCOVIRUSES OR ENCAPSIDATED PLASMIDS? 126 VARIETIES AND PREVALENCE OF YEAST KILLERS . 128 MODE OF ACTION OF KILLER TOXIN. 129 SUMMARY OF PHENOTYPES, dsRNA DETERMINANTS, AND PLASMID GENOTYPES OF S. CEREVISIAE KILLERS . 130 Nomenclature. 130 dsRNA Determinants . 131 Functional Model of Ml-dsRNA . 131 Plasmid Genotypes of S. cerevisiae Killers . 131 Plasmid Mutations in Ml-dsRNA . 133 Neutral and suicidal mutants ([KIL-n1J, [KIL-il]) . 133 Suppressive mutants ([KIL-sl]) . 133 Diploid-dependent mutant ([KIL-dj]). 134 STRUCTURAL COMPARISONS OF KILLER dsRNAs . 134 CELL CYCLE STUDIES OF dsRNA REPLICATION IN S. CEREVISIAE. 134 TRANSCRIPTION AND REPLICATION OF KILLER dsRNAs . 135 ROLE OF L-dsRNA SPECIES IN VLP CAPSID PRODUCTION AND Ml-dsRNA MAINTENANCE . 136 Nomenclature and Function of the Various L-dsRNA Species. 137 Comparison of Sequences of L-dsRNAs. 137 Capsid Proteins Encoded by the Various L-dsRNAs . 138 NUCLEAR MUTATIONS AFFECTING M-dsRNA MAINTENANCE . 138 Maintenance of Killer (mak) Genes: the KRBI Mutation . 138 Superkiller (ski) Mutants and the [KIL-b]Plasmid Mutant. 139 Significance of mak and ski (etc.) Mutations. 140 EFFECT of mak and ski MUTATIONS ON L-dsRNA MAINTENANCE . 140 [HOK], [EXLJ, AND [NEX]: VARIATIONS IN ABILITY OF LA TO MAINTAIN M-dsRNAs . 140 [HOKI AND LA-H. 141 [EXL], LA-E, and LA-HE . 141 L2A and L2A-H(EXLR) . 141 [NEX], LA-HN, and mktl,2 . 141 Exclusion of M2by Ml-dsRNA . 141 Conclusion: Mechanisms of Exclusion and Models for Control of dsRNA Replication . 141 T-, W-, and XL-dsRNAs . 142 cloand the Discovery of T and W . 142 Independent dsRNA Families and Their Roles in S. cerevisiae . 143 STRUCTURE OF THE Ml-dsRNA PREPROTOXIN GENE AND STEPS IN TOXIN MATURATION 143 Toxin Is Derived from a Glycosylated Intracellular Protoxin . 143 Toxin Is Encoded By Ml-dsRNA Which Also Determines Immunity . 143 Protoxin Maturation Involves the Normal Protein Secretion (sec) Pathway . 143 Conversion of Protoxin to Toxin Involves a TPCK-Sensitive Protease . 145 Effects of kexi, kex2, and rex Mutations. 145 SEQUENCE OF THE M1-P1 PREPROTOXIN GENE. 146 Localization Within the dsRNA of a cDNA Covering Most of the Gene . 146 Domain Structure of the Preprotoxin Processing Sites . 146 Analogies to Insulin and et-Factor Maturation . 146 Functional Analysis of the Toxin Subunit Structure and -y . 148 IN VIVO EXPRESSION OF PREPROTOXIN cDNAs. 149 EFFECT OF PLASMID MUTANTS ON TOXIN MATURATION . 149 CODON USAGE IN THE PREPROTOXIN GENE . 150 LINEAR DNA KILLER PLASMIDS OF K. LACTIS . 150
Efficient Handling of Protocol Stacks for Dynamic Software Packet Processing

New standards for 40 and 100 Gbit/s and beyond impose increasing demands for software packet processing frameworks. Protocol stacks used in high-speed packet processing frameworks are reduced to basic functionality to cope with the performance requirements. Development of sophisticated applications require manifold functionality from the protocol stack, while being flexible and extensible to allow support of newly developed protocols. This becomes increasingly important as for instance data-center operators apply more forms of packet encapsulation, generating complex protocol stacks. Existing examples for highperformance frameworks are not able to fulfill all these aspects or have to make compromises. We present the protocol stack of the libmoon framework, a novel design for dynamic protocol stacks based on code generation and JIT compilation. Defining the format of a new protocol header is the only action that has to be performed by a programmer. The desired protocol stack is generated automatically from this information, allowing combination of arbitrary headers. Thereby, a complex and full set of utility functions is provided to the application developer. We evaluate our protocol stacks using measurements in a VXLAN setup, which also highlight how the new protocol stack API allows to easily create applications in a flexible and intuitive manner.
Lack of association of cytomegalovirus with endemic African Kaposi's sarcoma.

12. Rao CR. Linear statistical inference and its applications. New York: Wiley, 1985:291-309 13. Esteban JI, Shih JW-K, Tai C-C, Bodner AJ, Kay JWD, Alter HJ. Importance of western blot analysis in predicting infectivity of anti-HTLV-III/LAV positive blood. Lancet 1985;2:1083-6 14. Curran JW, Morgan WM, Hardy AM, Jaffe HW, Darrow WW, Dowdle WR. The epidemiology of AIDS: current status and future prospects. Science 1985;229:1352-7 15. Kreiss JK, Koech D, Plummer FA, Holmes KK, Lightfoote M, Piot P, Ronald AR, Ndinya-Achola JO, D'Costa LJ, Roberts P, Ngugi EN, Quinn TC. AIDS virus infection of Nairobi prostitutes. Spread of the epidemic to East Africa. N Engl J Med 1986;314:414-8 16. Grant RM. Co-factors in seroconversion to the AIDSassociated retrovirus among homosexual men in San Francisco. Masters thesis, Berkeley, Calif: University of California, Berkeley, 1986 17. Levy JA, Kaminsky LS, Morrow WJW, Steimer K, Luciw P, Dina D, Hoxie J, Oshiro L. Infection by the retrovirus associated with the acquired immunodeficiency syndrome. Clinical, biological, and molecular features. Ann Intern Med 1985;103:694-9
Application of Amide Proton Exchange Mass Spectrometry for the Study of Protein‐Protein Interactions

This protocol describes amide proton exchange experiments that probe for changes in solvent accessibility at protein‐protein interfaces. The simplest version of the protocol, termed the “on‐exchange” experiment, detects protein‐protein interfaces by taking advantage of the fact that solvent deuterium oxide (D2O) molecules are excluded from the surface of a protein to which another protein is bound. A more complete version of the experiment can also be performed in which the rate of surface deuteration is initially measured separately for each of the proteins involved in the interaction, after which the deuterated proteins are allowed to complex and the rate of “off‐exchange” (i.e., replacement of surface deuterons by protons from solvent H2O molecules) at the resulting protein‐protein interface is measured. This version of the experiment yields additional kinetic information that can help to define the solvent‐inaccessible “core” of the interface.
Immunology of Escherichia coli: K antigen and its relation to urinary-tract infection.

The question as to whether or not the bacteria that cause urinary-tract infection (UTI) have special characteristics making them more virulent for the urinary tract has long been discussed. Thus, some are of the opinion that Escherichia coli strains of a few serotypes are especially nephropathogenic strains and more apt to cause UTI [1], while others are more sceptical of such characterization of strains [2, 3].
Evidence of Orbitofrontal Dysfunction in Sex Offenders

Sex offenders demonstrate a lack of executive regulation of behaviour that is suggestive of prefrontal system dysfunction. Prefrontal systems connect reciprocally with limbic and other subcortical structures that regulate sexual behaviour. Prior research demonstrates prefrontal dysfunction in other criminal populations and several neuropsychological studies and case reports suggest prefrontal, particularly orbitofrontal, dysfunction in association with sex offenses. In this study, sex offenders performed worse than controls on measures sensitive to orbitofrontal dysfunction: go/no-go, antisaccades, and delayed alternation. There was a trend toward differences on smell identification which did not reach significance but were in the predicted direction. Overall, the sex offenders showed difficulty on tasks involving response modulation according to learned rules.
Enzymatic activity of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 11: upregulated in breast and cervical cancers[S]

The conversion of lysophosphatidic acid (LPA) to phosphatidic acid is carried out by the microsomal enzymes 1-acylglycerol-3-phosphate-O-acyltransferases (AGPATs). These enzymes are specific for acylating LPA at the sn-2 (carbon 2) position on the glycerol backbone and are important, because they provide substrates for the synthesis of phospholipids and triglycerides. At least, mutations in one isoform, AGPAT2, cause near complete loss of adipose tissue in humans. We cloned a cDNA predicted to be an AGPAT isoform, AGPAT11. This cDNA has been recently identified also as lysophosphatidylcholine acyltransferase 2 (LPCAT2) and lyso platelet-activating factor acetyltransferase. When AGPAT11/LPCAT2/lyso platelet-activating factor acetyltransferase cDNA was expressed in CHO and HeLa cells, the protein product localized to the endoplasmic reticulum. In vitro enzymatic activity using lysates of Human Embryonic Kidney-293 cells infected with recombinant AGPAT11/LPCAT2/lyso platelet-activating factor-acetyltransferase cDNA adenovirus show that the protein has an AGPAT activity but lacks glycerol-3-phosphate acyltransferase enzymatic activity. The AGPAT11 efficiently uses C18:1 LPA as acyl acceptor and C18:1 fatty acid as an acyl donor. Thus, it has similar substrate specificities for LPA and acyl-CoA as shown for AGPAT9 and 10. Expression of AGPAT11 mRNA was significantly upregulated in human breast, cervical, and colorectal cancer tissues, indicating its adjuvant role in the progression of these cancers. Our enzymatic assays strongly suggest that the cDNA previously identified as LPCAT2/lyso platelet-activating factor-acetyltransferase cDNA has AGPAT activity and thus we prefer to identify this clone as AGPAT11 as well.
Vagus nerve stimulation therapy for partial-onset seizures

Objective: The purpose of this multicenter, add-on, double-blind, randomized, active-control study was to compare the efficacy and safety of presumably therapeutic (high) vagus nerve stimulation with less (low) stimulation. Background: Chronic intermittent left vagus nerve stimulation has been shown in animal models and in preliminary clinical trials to suppress the occurrence of seizures. Methods: Patients had at least six partial-onset seizures over 30 days involving complex partial or secondarily generalized seizures. Concurrent antiepileptic drugs were unaltered. After a 3-month baseline, patients were surgically implanted with stimulating leads coiled around the left vagus nerve and connected to an infraclavicular subcutaneous programmable pacemaker-like generator. After randomization, device initiation, and a 2-week ramp-up period, patients were assessed for seizure counts and safety over 3 months. The primary efficacy variable was the percentage change in total seizure frequency compared with baseline. Results: Patients receiving high stimulation (94 patients, ages 13 to 54 years) had an average 28% reduction in total seizure frequency compared with a 15% reduction in the low stimulation group (102 patients, ages 15 to 60 year; p = 0.04). The high-stimulation group also had greater improvements on global evaluation scores, as rated by a blinded interviewer and the patient. High stimulation was associated with more voice alteration and dyspnea. No changes in physiologic indicators of gastric, cardiac, or pulmonary functions occurred. Conclusions: Vagus nerve stimulation is an effective and safe adjunctive treatment for patients with refractory partial-onset seizures. It represents the advent of a new, nonpharmacologic treatment for epilepsy.
Nano-yarn carbon nanotube fiber based enzymatic glucose biosensor

A novel brush-like electrode based on carbon nanotube (CNT) nano-yarn fiber has been designed for electrochemical biosensor applications and its efficacy as an enzymatic glucose biosensor demonstrated. The CNT nano-yarn fiber was spun directly from a chemical-vapor-deposition (CVD) gas flow reaction using a mixture of ethanol and acetone as the carbon source and an iron nano-catalyst. The fiber, 28 µm in diameter, was made of bundles of double walled CNTs (DWNTs) concentrically compacted into multiple layers forming a nano-porous network structure. Cyclic voltammetry study revealed a superior electrocatalytic activity for CNT fiber compared to the traditional Pt–Ir coil electrode. The electrode end tip of the CNT fiber was freeze-fractured to obtain a unique brush-like nano-structure resembling a scale-down electrical ‘flex’, where glucose oxidase (GOx) enzyme was immobilized using glutaraldehyde crosslinking in the presence of bovine serum albumin (BSA). An outer epoxy-polyurethane (EPU) layer was used as semi-permeable membrane. The sensor function was tested against a standard reference electrode. The sensitivities, linear detection range and linearity for detecting glucose for the miniature CNT fiber electrode were better than that reported for a Pt–Ir coil electrode. Thermal annealing of the CNT fiber at 250 °C for 30 min prior to fabrication of the sensor resulted in a 7.5 fold increase in glucose sensitivity. The as-spun CNT fiber based glucose biosensor was shown to be stable for up to 70 days. In addition, gold coating of the electrode connecting end of the CNT fiber resulted in extending the glucose detection limit to 25 µM. To conclude, superior efficiency of CNT fiber for glucose biosensing was demonstrated compared to a traditional Pt–Ir sensor.
Duration Dependence in Sickness Absence: How Can We Optimize Disability Management Intervention Strategies?

Objective: The optimal timing of interventions during sickness absence remains difficult to determine, because we do not have a clear picture of the presence and type of duration dependence that exists. This study investigates the impact of an intervention by the occupational physician as well as of socioeconomic and work-related factors on duration dependence during sickness absence. Methods: Analyses were performed at the population level using data from a major longitudinal survey on work incapacity and return to work in The Netherlands. Several models of duration dependence are estimated. Results: Evidence is found for the presence of variable-duration dependence. Characteristics that influence duration dependence of the return-to-work (RTW) rate are identified. Conclusions: The findings imply that RTW intervention strategies should vary according to differences in workers' susceptibility to positive or negative duration-dependence effects.
ALD of in-doped ZnO

Atomic layer deposition (ALD) windows for ZnO and ZnS films using DEZn, H2S and H2O as precursors were determined and the deposited films were characterized. Doping of ZnO with In during ALD by periodic exposure to TMIn was studied with an emphasis on the structural properties of the films. XRD results show compressive stress in the film induced by the larger In atom, which leads to smaller grain size. Based on these results stacked layers of ZnOS/ZnO:In and sputtered ZnOS/ZnO:Al were deposited on CIGS thin films to compare the performance of the ALD TCO to that of our standard TCO. The finished cell with ZnO:In as TCO shows relatively low Jsc and Rse compared with the cell using sputtered ZnO:Al as TCO.
Prehension Synergies

ZATSIORSKY, V. M. , and M. L. LATASH. Prehension synergies. Exerc. Sport Sci. Rev., Vol. 32, No. 2, pp. 75–80, 2004. The precision grip requires the control of the normal and tangential forces exerted by the fingers as well as the control of the rotational equilibrium of the grasped object. Prehension synergies involve the conjoint changes in finger forces and moments during multifinger gripping tasks. Some of these adjustments are dictated by mechanics, whereas others are the result of a choice by the performer.
Establishing an online mentor database for medical students

focus on reflection in order to compare courses of action rather than selecting the most appropriate. In this sense, the CJLT is innovative as it allies cognitive apprenticeship with the development of critical thinking skills. Furthermore, students recognise the ethical conduct that is most coherent with professionalism as identified by experts, but point out that in ‘real-life’ experiences on hospital wards, conduct can be markedly different. We believe this reflects the hidden curriculum, signalled in the literature as a major impediment to professionalism education. Learning to conciliate espoused ethical conduct and future clinical experience, buttressed by insight into expert ethical decision making, is the chief added value of the CJLT for the meaningful development of professionalism. Finally, the user-friendly aspect of the CJLT is not a trivial matter. The CJLT we have implemented is completed online at times and at a pace determined by each student. Hence, it is truly an effective professionalism-learning tool that can be inserted easily into already heavy study schedules. We are encouraged to introduce the CJLT into residency and continuous professional development. Although it is too early to consider it as an assessment tool, we think it can be used to measure the development of professionalism competence in students over time.
The effects of anger in the workplace: When, where, and why observing anger enhances or hinders performance

Most anger research has adopted a within-person view, focusing on the effects of experienced anger on a person's feelings, cognition, and behavior. Less research has examined the effects of anger expressed by one person on other people in the workplace. We review available literature on the interpersonal effects of anger and propose a theoretical framework that addresses two main questions (1) What mechanisms can explain the effects of observed anger on other people? and (2) What factors may strengthen or attenuate these effects? We propose that observed anger affects observers’ performance via emotional and cognitive routes that are interrelated, and that this effect depends on the properties of the expressed anger, the situation in which the anger occurs, and the task being performed by the observer.