Miracle-dz/UniFAR-FTUs huggingface dataset:
Classification of Breast Cancer using Differential Evolution and LeastSquares Support Vector Machine

Breast Cancer is becoming a leading cause of death among women in the whole world; meanwhile, it is confirmed that the early detection and accurate diagnosis of this disease can ensure a long survival of the patients. This paper proposes a hybrid classification algorithm using Differential Evolution (DE) and Least Squares Support Vector Machine (LS-SVM). LS-SVM technique is used for classification. Since LS-SVM classifier is so sensitive to the changes of its parameter values, DE algorithm is used as an optimization technique for LS-SVM parameters. This will guarantee the effectiveness of the hybrid algorithm by searching for the optimal values of the classifier. The proposed algorithm is implemented and evaluated on Wisconsin Breast Cancer Dataset (WBCD) from UCI Repository of Machine Learning Databases. The proposed algorithm was compared with different classifier algorithms which were applied on the same database. The experimental results showed the superiority of the proposed algorithm that could achieve a classification accuracy of 99.75%.
Gene diversity analysis of mitochondrial DNA, microsatellites and allozymes in landlocked Atlantic salmon

This study investigates the patterns of genetic diversity detected in allozymes, mtDNA, and microsatellites, in order to assess their relative efficacy to differentiate sympatric landlocked salmon populations and to estimate changes in genetic diversity between wild and first-generation hatchery fish. Overall, the three genetic markers indicated a genetic differentiation between two sympatric populations of Lake Saint-Jean, Quebec. MtDNA and microsatellites also showed significant differences between wild and first-generation hatchery fish originating from the same river. Allozyme analysis was the most limited approach due to the low genetic diversity detected and the necessity to kill specimens. Although low polymorphism was found in mtDNA, it was the most discriminant marker between wild populations. Microsatellite analysis appears to be a promising approach due to its high sensitivity in differentiating wild populations, in detecting changes in allele composition between wild and first-generation hatchery fish and its potential for increased resolution by augmenting the number of polymorphic loci. Given the benefits and disadvantages of the three methods, the combination of mtDNA and microsatellite analyses will best address our research objectives.
A Comparative study on Efficacy of 10% and 20% Mannitol for Inducing Diuresis During Renal Transplant Surgery

Objective: Mannitol is one of the most commonly used osmotic diuretics during renal transplant surgery. Two concentrations of mannitol, 10% and 20%, are available, however there is no consensus about which concentration is to be preferred. The purpose of this study was to compare between the efficacy of the two concentrations of mannitol for inducing diuresis during renal transplant surgery and the need for further diuretics (furosemide). Methods: A prospective study was carried out on 60 patients of either sex undergoing living donor renal transplantation in Zheen International Hospital between April 2011 and May 2015 for the end-stage renal failure. Patients were assigned into two groups, group 1 received 10% mannitol and group 2 received 20% mannitol. All patients evaluated preoperatively by the anesthetist, immunosuppression was initiated the day before the surgery using combination of immunosuppressant drugs. General anesthesia induced with thiopentone and maintained with atracurium and isoflurane, vital parameters monitored, the donated kidney was placed retroperitoneally in the iliac fossa and anastomosis between renal and iliac vessels were established. Normal saline 0.9% used as intravenous fluid, once venous anastomosis started diuresis initiated with mannitol 10% or 20% (2-3 ml/kg). The urine output of the patients was monitored and furosemide was given as needed with the aim of at least 2 ml/kg/hr of urine output. Results: The demographic characteristics between both study groups were comparable (p > 0.05). Patients treated with 10% mannitol (group 1) were found to require significantly less overall dose of mannitol as compared to patients received 20% mannitol (group 2) (p 0.05). Conclusion: A lower dose of mannitol using lower concentration (10%) is more effective in terms of need of overall dose in grams for inducing diuresis with less need for furosemide compared to higher concentration (20%) of mannitol.
Optimization and Stability studies of siRNA for Significant Inhibition of Dengue (DENV-2) Viral Replication in Vero cells

Optimization and Stability studies of siRNA Abstract RNA interference (RNAi) is a highly conserved, specific and selective biological response of gene regulation mechanism and has been widely exploited for designing novel drug targets to treat infections caused by pathogens including viruses. In the previous study, one of the promising sh-5b RNA (short hairpin RNA, sh5b) construct was targeted to the conserved sequence within the 51-NTRs (non-translated regions) of all Dengue serotypes. The current study report the stability (up to 24 months) of recombinant adenovirus (rAd) engineered to express sh-5b RNA for DENV-2 replication inhibition. Stability study was done by gene specific PCR, where as the effect of sh-5b RNA in attenuating DENV-2 replication was further validated by One step RT-PCR by TITAN. The rAds harboring sh-5b RNA to target dengue serotypes might serve as an efficient alternative to conventional drugs for therapeutic intervention to treat DENV infections in humans.
3 D vs . 2 D Channel Capacity of Outdoor to Indoor Scenarios Derived from Measurements in China and New Zealand

Three dimensional (3D) Multiple Input Multiple Output (MIMO) is considered as one key technology for 5th Generation mobile communication systems. However, can the capacity derived from a 3D channel impulse response (CIR) better approximate the corresponding capacity derived from the measured CIR? Is there a substantial improvement in the capacity of 3D MIMO system in comparison to the classical 2D case? To answer these questions, extensive field measurements were conducted for the outdoor to indoor scenarios in China and New Zealand. Key channel parameters are extracted from the measured channel impulse response via the space-alternating generalized expectation-maximization algorithm, followed by the reconstruction of the 32 × 56 CIR according to 2D and 3D channel model. Then CIRs are used to evaluate the channel capacity and comparative simulation results demonstrate that the 3D MIMO capacity closely approximates the capacity predicted with practical CIRs. Moreover, obvious enhancements in the capacity of 3D channel is observed in comparison to 2D case. In addition, the distribution of eigenvalues and the number of contributing eigenvalues are also investigated.
Seroepidemiological survey of bovine tick-borne infections in theBlack Sea Region of Turkey

Babesiosis, theileriosis, and anaplasmosis are the tick-borne diseases of cattle in most of the tropical areas and Turkey. A total of 270 cattle were randomly selected from 27 villages and 77 farms in the Black Sea Region of Turkey for the determination of infections by Babesia bigemina and Anaplasma marginale by using the indirect fluorescent antibody (IFA) test and the competitive enzyme-linked immunosorbent assay (cELISA). Of those, 242 and 256 sera were also analyzed for antibodies against Theileria annulata and Babesia bovis infections using the IFA test, respectively, during the period of June 2006 to June 2007. Of the 256 tested sera, 99 (38.6%) were positive for B. bovis; from the total 270 sera, 40 (14.8%) were positive for B. bigemina; of the 242 sera tested, 31 (12.8%) were positive for T. annulata by IFA; and from the total 270 sera, 102 (37.8%) were positive for A. marginale by cELISA. A total of 1125 ixodid ticks were collected and 10 species were identified. Antibodies produced by infections with Babesia spp. , Anaplasma spp. , and Theileria spp. were found highly prevalent. Infections caused by the agents and the tick species may cause severe economic damage to cattle production from the Black Sea Region of Turkey.
Neural adaptations in isometric contractions with EMG and force biofeedback

"Adaptaciones neurales en contracciones isometricas con biofeedback EMG e de fuerza. " Este estudio evaluo las adaptaciones neurales de cuadriceps durante contracciones isometricas usando los signos de fuerza y ​​electromiografia (EMG) como biofeedback. Cuarenta y dos sujetos fueron divididos en tres grupos: EMG, probado con biofeedback EMG; Fuerza, probado con biofeedback de fuerza; y control, probado sin biofeedback. Las avaluaciones se realizaron pre/post pruebas para determinar la maxima fuerza y amplitud EMG durante contracciones isometricas voluntarias maximas (CIVM). Las pruebas consistieron en series de CIVM en que los sujetos fueron encorajados a cruzar el umbral de fuerza y EMG ​​ inicialmente determinados. La amplitud EMG del vasto lateral y fuerza de los extensores de la rodilla aumento significativamente en todos los grupos al comparar las avaluaciones pre y post pruebas (p < 0,05). El porcentaje de ganancia EMG fue significativamente diferente entre los grupos Fuerza y ​​control (p < 0,01), mientras que el porcentaje de aumento de la fuerza no fue diferente entre los grupos. Biofeedback de fuerza fue mas eficaz en producir adaptaciones neurales.
Influence of Geographical and Climatic Conditions on Camptothecin Content of Nothapodytes nimmoniana

Camptothecin, topoisomerase I-DNA inhibitor, has been evaluated in methanolic extract of various parts of Nothapodytes nimmoniana (J. Graham) Mabberly (Family Icacinaceae) collected in the month of February from different regions (Mahabaleshwar and Patan regions of Maharashtra state and Sirsi region of Karnataka state) of Western Ghats, India, using high performance liquid chromatography. Quantification was performed with the regression analysis and the method was validated as per International Conference of Harmonization (ICH) guidelines. In regard to various plant parts, maximum concentration of camptothecin was found in root (2.62%) collected from Mahabaleshwar, Patan (1.21%) and Sirsi (0.88%) regions followed by stem collected from Patan (1.45%), Sirsi (0.70%) and Mahabaleshwar (0.43%) regions. The lowest concentration of camptothecin was found in leaves collected from Sirsi (0.29) region, followed by Patan (0.37) and Mahabaleshwar (0.70%) region. Fruits collected from Mahabaleshwar region contain maximum concentration of camptothecin (0.63%) whereas fruits from Patan region contain minimum concentration of camptothecin (0.36%). There was a 2-fold higher concentration of camptothecin observed in roots from Mahabaleshwar region than roots from Sirsi and Patan region. So it is evident that geographical and climatic conditions have remarkable influence in the content of camptothecin in N. nimmoniana .
Treatment Of A Patient With Thoracolumbar Scoliosis Utilizing A Regional Interdependence Approach Including Components Of The Schroth Method: A Case Report

3 Background and Purpose 4 Spinal deformity is a challenging spinal disorder in adults. A scoliotic curve of >10 5 degrees exists in up to 12% of the population and while surgery is the definitive measure, there is 6 limited evidence to guide non-surgical treatment. This case investigated traditional physical 7 therapy (PT) treatment utilizing a Regional Interdependence Approach (RIA) and components of 8 the Schroth method for a patient with chronic low back pain (CLBP). 9 Case Description 10 A 66 year old male presented with CLBP, worst upon rising in the AM with (6/10 11 NPRS). Imaging demonstrated thoracolumbar dextroscoliosis, bilateral foraminal narrowing and 12 associated spondylolisthesis of the fifth lumbar vertebrae. A RIA exam revealed mobility deficits 13 of thoracolumbar spine, instability of L5-S1, and a 1.38” leg length discrepancy. A 14 comprehensive treatment approach was used including lumbar stabilization exercises and 15 postural therapy, including components of the Schroth method. 16 Outcomes 17 Following 12 weeks, pain improved from 6/10 to 4/10, with the patient reporting no pain 18 when arising from bed. 30-second sit to stand improved from five to eight. Following 19 implementation of a shoe lift visible changes were noted in pelvic symmetry. However, the 20 degree of scoliosis appeared unchanged and no subjective improvements were noted on the 21 Roland-Morris Low Back Pain Questionnaire (RMLBPQ). 22
Skipping unnecessary structural airframe maintenance using an on-board structural health monitoring system

Structural airframe maintenance is a subset of scheduled maintenance, and is performed at regular intervals to detect and repair cracks that would otherwise affect the safety of the airplane. It has been observed that only a fraction of airplanes undergo structural airframe maintenance at earlier scheduled maintenance times. But, intrusive inspection of all panels on the airplanes needs to be performed at the time of scheduled maintenance to ascertain the presence/absence of large cracks critical to the safety of the airplane. Recently, structural health monitoring techniques have been developed. They use on-board sensors and actuators to assess the current damage status of the airplane, and can be used as a tool to skip the structural airframe maintenance whenever deemed unnecessary. Two maintenance philosophies, scheduled structural health monitoring and condition-based maintenance skip, have been developed in this article to skip unnecessary structural airframe maintenances using the on-board structural health monitoring system. A cost model is developed to quantify the savings of these maintenance philosophies over scheduled maintenance.
Linear differential algebraic equations with constant coefficients

Differential-algebraic equations (DAEs) arise in a variety of applications. Their analysis and numerical treatment, therefore, plays an important role in modern mathematics. The paper gives an introduction to the topics of DAEs. Examples of DAEs are considered showing their importance for practical problems. Some essential concepts that are really essential for understanding the DAE systems are introduced. The canonical forms of DAEs are discussed widely to make them more efficient and easy for practical use. Also some numerical examples are discussed to clarify the existence and uniqueness of the system's solutions. Keywords: differential-algebraic equations, index concept, canonical forms. DOI: 10.3329/diujst.v4i2. 4365 Daffodil International University Journal of Science and Technology Vol.4(2) 2009 pp.28-35
The Links between Fertilizer and Nutrition in South Asia and Africa

The following literature review explores the links between the use of macroand micronutrient fertilizers and human nutrition. The review focuses on the academic literature covering the effects of fertilizers on plant and human nutrition in areas with nutrient deficient soils, with a particular emphasis on South Asia and Sub-Saharan Africa. Additionally, the review identifies a few of the primary institutions involved in fertilizer research.
Les entreprises dans la crise: premiers résultats d’une enquête européenne

Dans le cadre d’une enquete menee en collaboration avec la BCE et vingt-cinq banques centrales de l’Union europeenne, la Banque de France a interroge 1 156 entreprises francaises pour comprendre l’impact de la crise sur leur environnement economique et leurs pratiques salariales entre 2010 et 2013.
Physical performance of Finnish futsal players, analysis of game intensity and fatigue in official futsal games

Ville Vähäkoitti. Physical performance of Finnish futsal players, analysis of intensity and fatigue in official futsal games. Faculty of Sport and Health Sciences, University of Jyväskylä, Science of Sport Coaching and Fitness Testing, Master Thesis, 60pp. Introduction. Futsal has grown notably in last years and have over 12 million players worldwide. Futsal is a high-intensity indoor sport where burst of multi-planar movements varies with short periods of rest. Futsal is played on a court sized 40 x 20 m for two halves of 20 min, where clock is stopped when ball is out of play. Purpose of this study was to find out physical performance of Finnish futsal players and analyse intensity and fatigue in official futsal games. Methods. Two Finnish Futsal League teams were involved (n = 19), age 26.3 (± 3.0 years), body mass 76.4 (± 6.2 kg), height 178.7 (± 5.7 cm), BMI 23.9 (± 1.4 kg/m) and body fat % 12.3 (± 4.0 %). Measurement were done in the middle of the season 2016-2017, during two months’ period. Two games from both teams were analysed. Measuring included physical performance tests (sprint test 5-m and 20-m, agility test, CMJ, isometric leg press and maximal treadmill running test) and game measurements (HR, movement distances and velocities, playing time, accelerations and deceleration). CMJ and lactate were measured before, middle and after futsal game to assess fatigue. Results. Sprint times were 1.03 (± 0.04 s) in 5-m and 3.01 (± 0.07 s) in 20-m. Agility test time was 6.87 (± 0.25 s). CMJ result was 41.8 (± 5.6 cm) and isometric leg press 5327 (± 1070 N). In the maximal treadmill running test HRmax was 191.6 (± 9.5 bpm), VO2max 59.8 (± 5.4 ml/kg/min) and VEmax 171.9 (± 20.8 l/min). Futsal players moved on average 4463.0 (± 1169.3 m) on intensity 54.0 (± 13.2 m/min) during the futsal games. Sprinting occurred on average 39.7 (± 17.2) times in the games. HRmax achieved during the futsal games was 191.6 (± 9.9 bpm), and average HR 147.0 (± 16.9 bpm). Fatigue did not occur during or after the futsal games when measured as CMJ or lactate (p > 0.05). Conclusions. From the results of the physical performance tests, it seems that Finnish futsal player’s physical fitness is comparable to play futsal in high level. During Finnish Futsal League games the distance moved is similar to those measured in literature, but the intensity lower when expressed as % HRmax, distance moved in one minute or in different speed zones. Because fatigue was not evident during the games, higher-intensity tactic or less substitutions to the key players could be used. In general, consistency in research methods would ease comparison of different studies. More futsal research is needed to understand the fundamentals of the sport that is growing and evolving constantly.
Social Cognition Impairments

Cognitive impairments in multiple sclerosis (MS) are heterogeneous and their rate varies between 43% and 70%. A less studied aspect of cognition is social cognition, which is not a uniform theoretical construct. It includes emotion perception, prosody, empathy, theory of mind (ToM) and assessment of mood. In addition to progressive physical disability, social cognitive impairments are a reason for job loss in 24–80% of patients with MS, increased divorce rate, dissolution of partnerships and social communication difficulties. Social cognitive impairments are the result of disruptions in the mentalization network at the neuroanatomical, neurochemical and/or genetic level, which can lead to malfunc‐ tions in the dopaminergic–serotoninergic system and to compromising the develop‐ ment of neuroanatomical targets within the network. The wide dissemination of demyelinating lesions and cortical thinning typical of patients with MS often lead to anatomic and functional disorders of the above‐mentioned specific brain structures. A correlation has been established among specific cortical areas involved in emotion identification from facial expression (right and left fusiform face area, frontal eye), emotion processing (right entorhinal cortex) and socially relevant information (left temporal pole). The most active brain region involved in social cognitive processing is the medal frontal cortex (MFC), which is described as the brain's social cognitive center. During perform‐ ance of various sociocognitive tasks for mental state attribution, common areas of increased activation in the medial prefrontal gyrus and the temporoparietal junctions are registered bilaterally, while the area of the medial prefrontal cortex (the paracingulate cortex) is the only region uniquely activated by the performance of ToM. Most MRI studies of patients with MS found a correlation between the cognitive and/or affective disorders, on the one hand, and lesion localization, total lesion load, or cerebral atrophy, on the other. A significant correlation was also reported between © 2016 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. abnormal activities in specific cortical zones on fMRI, on the one hand, and clinical manifestation, conventional MRI findings and behavioral changes, on the other. Altered patterns of brain activity were found in all clinical phenotypes of MS, including when cognitive abilities were intact and/or restored, social cognitive dysfunction in MS actually affects all stages of the disease and all types of clinical course. The cortical plastic changes are a dynamic phenomenon that can be modulated by external factors. This phenomenon would facilitate the mapping of individual strategies for adequate treatment and rehabilitation of each patient.
On the psychological and motivational processes linking job characteristics to employee functioning: Insights from self-determination theory

ABSTRACT The aim of this study was to provide insight into the differential relationships between job characteristics (job demands and resources) and employee functioning by examining the psychological and motivational processes involved. Drawing on self-determination theory, we tested a model in which job demands are positively related to negative manifestations of employee functioning (psychological distress and psychosomatic complaints) through psychological need frustration and low-quality work motivation (controlled motivation), whereas job resources are positively related to positive manifestations of employee functioning (work engagement and job performance) through need satisfaction and high-quality work motivation (autonomous motivation). Data were collected from 699 Canadian nurses. Structural equation modelling (SEM) results support the proposed model: psychological needs and work motivation partially mediated the relationship between job characteristics and employee functioning. Specifically, job demands negatively predicted employee functioning (high distress and psychosomatic complaints, low engagement and performance) through need frustration and controlled motivation. In contrast, while positively predicting need satisfaction and negatively predicting need frustration, job resources fostered optimal work motivation (more autonomous and less controlled motivation) and employee functioning. The implications for self-determination theory (SDT) and research on occupational health and stress are discussed.