Miracle-dz/UniFAR-FTUs huggingface dataset:
Recolha de dados sobre consumo de medicamentos e/ou suplementos à base de plantas medicinais numa amostra da população de Lisboa e Vale do Tejo

Este trabalho teve como objectivo investigar os habitos e conhecimentos gerais de uma amostra da populacao de Lisboa e Vale do Tejo relacionados com o consumo dos suplementos e medicamentos a base de plantas medicinais. Realizou-se um estudo nao experimental descritivo, transversal, atraves de um questionario anonimo, confidencial e voluntario a 367 individuos, preenchido pelas entrevistadoras, mediante as respostas obtidas dos entrevistados, sendo a amostra obtida por conveniencia. Os individuos pertenciam maioritariamente ao sexo feminino 74,7% (274/367) e a classe etaria dos 20 aos 29 anos, 52,0% (191/367). Dos inquiridos, 48,8% (179/367) consomem medicamentos e/ou suplementos a base de plantas e destes, 25,7% (46/179) afirmam consumir medicamentos a base de plantas medicinais enquanto 20,1% (36/179) afirmam consumir suplementos alimentares a base de plantas. Do total dos inquiridos que consomem medicamentos e/ou suplementos a base de plantas, 2,8% (5/179) responderam que ja sentiram reaccao adversa, 93,9% (168/179) disseram nao ter sentido qualquer reaccao adversa e 3,4% (6/179) nao sabe ou nao se lembra. Inquiridos sobre a diferenca entre medicamentos a base de plantas e suplementos alimentares a base de plantas, 67,6% (121/179) afirmam conhecer a diferenca e 32,4% (58/179) nao conhecem a diferenca entre medicamentos e suplementos alimentares
The Acromegaly Syndrome

SUMMARY One hundred and fifty-five acromegalics, 76 males (mean age 44 ± 1.3 years) and 79 females (45 ± 1.4 years) were studied. The frequency of clinical features were: acral enlargement 100 per cent, hyperhidrosis 65 per cent, headache 55 per cent, paraesthesiae 49 per cent, cardiac problems 34 per cent, hypertension 32 per cent, diabetes mellitus (clinical and chemical) 27 per cent, and visual field defects 6 per cent Signs and symptoms, and particularly headache, did not show any relation with the size or shape of pituitary tumours, nor with growth hormone (GH) values, age, sex or weight Mean of GH values at 60, 90 and 120 minutes during a GTT averaged 135 mIU/I, range 8–1833. Diabetes mellitus was more frequent and severe in patients with higher GH values, occurring in 32 per cent of patients with mean GH values ≧50 mIU/1 and only in 16 per cent of the rest (p < 0.05). GH values correlated positively with size of tumours. Forty-nine per cent of patients presented with entirely intrasellar tumours, 27 per cent with suprasellar extensions and 23 per cent with partially empty sellae. The mean GH (238 mIU/I) of patients with suprasellar extensions was significantly higher (p < 0.004) than those of the others. Younger acromegalics showed a tendency to larger tumours. Early treatment of acromegaly, particularly in young patients and those presenting with high GH values, is recommended.
Influencia del grado de lesión neurológica sobre la eficacia de la terapia celular en un modelo de traumatismo craneoencefálico grave

espanolObjetivo: Determinar si el nivel de deficit neurologico influye en la eficacia de la terapia celular con celulas madre mesenquimales (CMM) de la medula osea en un modelo experimental cronico de lesion cerebral traumatica. Material y metodos: Se sometio a ratas Wistar adultas a un modelo de lesion cerebral traumatica. Dos meses despues, se clasificaron en funcion de su nivel de deficit neurologico mediante dos tests funcionales: Escala de valoracion sensitivo-motora y Tiempo de permanencia en la zona interior (Video-Tracking-Box test, VTB test). Se inyecto suero salino solo o CMM en suero salino en el tejido cerebral danado de los animales que obtuvieron la clasificacion neurologica de lesion moderada o grave segun el nivel permanente de su deficit funcional. Todos los animales se evaluaron durante los dos meses siguientes para determinar la posible eficacia de la administracion de las CMM. Al finalizar el estudio, los animales se eutanasiaron y se estudiaron sus cerebros. Resultados: Se constata una recuperacion funcional significativa en los animales con lesion moderada que recibieron las CMM, pero no en los animales con lesion grave cuando se compara con los controles. Conclusiones: Las conclusiones obtenidas sugieren que la gravedad de la lesion neurologica puede influir en la potencial eficacia de la terapia celular cuando es aplicada en una lesion cerebral traumatica cronica. EnglishObjective: To study if the level of neurological deficit influences the efficacy of cell therapy with bone marrow stromal cells (BMSC), in an experimental model of chronic traumatic brain injury (TBI). Material and methods: Adult Wistar rats were subjected to a model of traumatic brain injury. Two months later they were classified according to their level of neurological deficit. For that, two functional tests: Scale of sensory- motor assessment and time spent in the inner zone in the Video-Tracking-Box test, were used. Saline alone or BMSC in saline was injected into the damaged brain tissue of animals suffering a permanent level of functional deficit classified as moderate or severe. All experimental groups were evaluated during the next two months to determine the potential effectiveness of the intracerebral administration of BMSC. At the end of the study animals were euthanized and their brains were studied. Results: The results show a significant functional recovery in animals with moderate injury who received BMSC, but there was no significant recovery in animals with severe traumatic brain injury when compared with controls. Conclusion: The severity of neurologic injury may influence the potential efficacy of cell therapy applied to chronic TBI.
Hepatic Hydatid Cyst and IntraperitonealFree Hydatid Cyst

Hydatid disease is relatively frequent in our country and non-invasive ultrasonic imaging techniques have made possible an earlier diagnosis prior to serious complications. Human hydatid disease usually occurs by infestation with Echinococcus granulosus and less frequently with Echinococcus multiocullaris. A twelve-year old girl fell from the swing 12 days ago. Acute abdomen was suspected, and she was operated under emergency conditions. Exploration of the abdomen soon revealed a giant cystic lesion formation, and this development did not fit the development of hydatid cyst pathophysiology.
Disorders of the Autonomic Nervous System

lesion in the efferent pathway. The alternative is to test sweating. A heat cradle is placed over the patient's trunk and he is warmed until the central temperature has risen at least 10C. He should then sweat, and if he does not it is usually correct to conclude that there is a sympathetic lesion in the efferent pathways. If there is such a lesion, it may be preganglionic (either immediately or within the central nervous system) or postganglionic. Postganglionic fibres can be tested by applying faradism to the skin or injecting acetylcholine intradermally. Either of these procedures produces an axon reflex in postganglionic fibres which results in sweating and pilo-erection in the neighbourhood (Barany & Cooper 1956). If these axon reflexes are present in a patient known to have an efferent sympathetic lesion, the lesion must be proximal to the ganglia. A recent example of the application of such tests is patient N W, mentioned above and fully reported elsewhere (Johnson et al. 1966). He was a man of 54 who for four and a half years complained of fainting when he stood up, consciousness returning when he lay down. Records of the blood pressure demonstrated that he had orthostatic hypotension and that he had lost his circulatory reflexes (Fig 1B). He also mentioned that he ceased to sweat at the time his symptoms began and we confirmed this. The acetylcholine test suggested that postganglionic fibres were intact, so it seemed probable that he had an efferent sympathetic lesion proximal to the ganglia. The patient died and Dr D R Oppenheimer showed that the cells in the intermediolateral columns of the dorsal spinal cord, that is the cells of the preganglionic fibres, were greatly diminished in number.
Effects of Previous Calf Management on Feedlot and Carcass Traits

Effects of Previous Calf Management on Feedlot and Carcass Traits. (December 2011) Bobby Cleave Bingham, B.S., Texas A&M University Chair of Committee: Dr. Chris Skaggs In 1999-2000, the Texas A&M University Ranch to Rail Program evaluated 1311 steers in two feedlots. The first was the Swisher County Cattle Company in Tulia, Texas and the other was Hondo Creek Cattle Company in Edroy, Texas. Data were collected on several traits, but from this project emphasis was placed on preweaning (PreVac) and postweaning (PosVac) vaccinations and the potential influence on growth and carcass traits. Independent variables used in the analyses were location of the feedyard (LOC), PreVac, PosVac, PreVac*PosVac, LOC* PreVac, LOC*PosVac, LOC* PreVac*PosVac, Ranch of origin (RANCH) nested within LOC* PreVac*PosVac, number of days from weaning to shipping to the feedyard (WNTSHP), and days on feed (DOF). Dependent variables evaluated for live cattle traits were average daily gain (ADG), medicine costs (MED), and initial value upon arriving at the feedyard. Dependent variables evaluated for carcass traits were hot carcass weight (HCW), ribeye area (REA), yield grade (YG), and gross value (GROSS). RANCH (P < 0.0001) and DOF (P < 0.0001) had large impacts on ADG.
Recruitment Criteria and Training in Human Resources Development: A Case Study of Women Office Workers at an Institution of Higher Education in Saudi Arabia

This study examines employee recruitment criteria and training opportunities, uses a sample of 185 Saudi women office workers. It was found that the majority of the employees had a bachelor’s degree, but had no formal qualification in administration, had no experience in similar jobs, did not do jobs which corresponded to their educational major, and felt that their jobs did not make use of their skills and abilities. Many of them also seemed to be underemployed since not all lower level administrative jobs necessarily required a bachelor’s degree. It was also found that training programs were offered to employees, and the majority who attended indicated that the training was valuable. On the other hand, the majority of the respondents who received training attended only one training program and were unable to apply what they have learned. Almost half of the employees had never attended any form of training program. More than three fourth have not been offered training on any regular basis. On the basis of the previous findings recommendations are proposed.
Uso dos artefatos de contabilidade gerencial: Comparativo entre os hospitais acreditados no brasil com os não acreditados da cidade de manaus (am)

The accounting artifacts are the instruments used to produce information and achieve business efficiency. The hospital accreditation is an hospital certification aimed at improving quality services in healthcare. But, has not yet been researched whether there are differences in the use of management accounting artifacts in the hospital accredited entities and non-accredited in Brazil. The research has as a general objective: To analyze the management accounting artifacts in accredited hospitals in Brazil and not accredited in Manaus city (AM). This study is a exploratory, quantitative research, conducted through survey. The research population is 17 hospitals, being 12 accredited and 5 non-accredited. Finally, the research concludes that there is a difference in the use of accounting artifacts between accredited hospital entities and non-accredited, emphasizing the artifact "Balanced Scorecard (BSC)". Keywords: Artifacts. Management accounting. Accreditation. Hospitals. Controller.
Oxidative stress and antioxidants in cancer prevention

Introduction: oxidative stress is involved in carcinogenesis. Consequently, the reinforcement of cellular defensive antioxidant mechanisms has been considered as strategy for cancer prevention. Objective: to evaluate the role of oxidative stress in the carcinogenesis process as well as the utility and modalities of the use of antioxidants in cancer prevention. Methods: a review was performed through the consultation of Google, LILACS, PubMed and Hinari. Review articles published in the last five years, systematic reviews and meta-analysis about the evaluation of antioxidants for cancer prevention were selected. Results: the carcinogenic mechanisms of oxygen reactive species, and the benefits and threats of antioxidant supplementation are discussed. Finally, the possible impact on oxidative stress control, of implementation of the WHO Global Strategy on Diet Physical Activity and Health is analyzed, empathizing in the anticarcinogenic mechanisms of different phytochemicals. Conclusions: the promotion of healthy habits which avoid the generation of oxygen reactive species, together with the intake of antioxidants as dietary components could lead to the appropriate balance oxidants/antioxidants and consequently to cancer prevention.
Recidive di neoplasia uterine dopo trattamento chirurgico: caratteristiche alla risonanza magnetica e loro modificazioni dopo radio-chemioterapia concomitante

Purpose. Our primary objective was to describe the magnetic resonance (MR) imaging patterns of recurrent uterine cancer after surgery and their changes following concurrent chemoradiation. The secondary objective was to identify MR imaging predictors of outcome. Materials and methods. Twenty-two consecutive women with biopsy-proven recurrent uterine cancer after surgery (cervix 13 patients, endometrium nine patients) were enrolled in this prospective study. Inclusion criteria were MR imaging at diagnosis and during follow-up and eligibility for concurrent chemoradiation. MR images were assessed for signal intensity of the pelvic relapse on T2
The Effect of Aqua Extract of Saffron with Resistance Training on Glycemic Indexes of Streptozotocin Induced Diabetic Rats

Background & aim: According to the proven effectiveness of saffron resistance and physical activity on diabetes, the aim of this study was to evaluate the effect of glycemic indexes of saffron combined with resistance training on streptozotocin induced diabetic rats. Methods: The present experimental study was conducted on 36 adult male rats. After induction of diabetes, the rats were randomly divided into four equal groups, resistance exercise (five days a week, for six days) and saffron extract (25 mg/L daily), resistance exercise combined with saffron extract and control groups. After a period of six weeks, glycemic indexes were measured. The gathered data were analyzed by klomogrov – Smirnov, one-way ANOVA and Tukey tests. Results: The results showed that fasting glucose in saffron aqua extract combined with resistance training group was significantly lower than both control and the RT groups ( p=0,014). Glycosylated hemoglobin group of saffron combined with resistance training was lower than the control group (p=0.011). Insulin resistance combined with resistance training in saffron aqua extract was lower than the control group (p=0.011). Conclusion: Six weeks of resistance training and consumption of saffron alone had a significant effect on glycemic indexes. However, saffron supplements with resistance training had a greater effect on control of fasting blood glucose.
MULTIDIMENSIONAL ANALYSIS IN THE CREATION OF MEDICAL CLUSTERS IN ŁÓDŹ – A CONCEPTUAL WORK

This article aims at presenting a concept of the way entities that provide medical services should be selected for clusters. A medical cluster is a designated group of entities that represent complimentary competencies and are connected organisational, legal, financial and scientific interdependencies. A medical cluster is oriented to benefit from a synergy effect to support patients, the state budget and science. The research employed a multidimensional data analysis. Firstly, a hierarchical grouping procedure was used to distinguish groups of hospitals that have similar medical competencies. Then, division criteria that characterise competence differences within the groups in question were found. This way, groups of dissimilar (the most dissimilar) hospitals were obtained. Subsequently, on the basis of a minimal distance criterion, one entity was selected from each group to obtain new groups of entities that were decisively different in the context of medical services offered and simultaneously situated in the close vicinity to one another. These two aspects may offer some premises to initiate co-operation between the entities subject to the research within a given medical cluster.
GEOGRAPHIC TONGUE: CASE REPORT AND LITERATURE REVIEW

Geographic tongue (Benign migratory glossitis, erythema migrans) is an asymptomatic inflam- matory disorder of tongue of unknown etiology. This disease is characterized by erythematous areas showing raised greyish or white circinate lines or bands with irregular pattern on the dorsal surface of the tongue and depapillation. The objective in presenting the case report and literature review is to discuss the clinical presentation, associated causative factors and management strategies of geographic tongue. Key Word: Geographic tongue.
The European Prevention of Alzheimer’s Dementia (EPAD) Longitudinal Cohort Study: Baseline Data Release V500.0

Background The European Prevention of Alzheimer’s Dementia (EPAD) Programme is a pan-European project whose objective is to deliver a platform, adaptive, Phase 2 proof of concept (PoC) trial for the secondary prevention of Alzheimer’s dementia. A component of this platform is the Longitudinal Cohort Study (LCS) which acts as a readiness cohort for the PoC Trial as well as generating data for disease modelling work in the preclinical and prodromal phases of Alzheimer’s dementia. Objectives The first data wave has been collected, quality checked, released and now available for analysis to answer numerous research questions. Here we describe the results from key variables in the EPAD LCS with the objective of using these results to compliment analyses of these data in the future. Design EPAD LCS is a cohort study whose primary objective is as a readiness cohort for the EPAD PoC Trial. As such recruitment is not capped at any particular number but will continue to facilitate delivery of the EPAD PoC Trial. Research Participants are seen annually (with an additional 6 month visit in the first year). Setting The EPAD Trial Delivery Network comprises currently 21 centres across Europe. Participants Research participants are included if they are over 50 years old and do not have a diagnosis of dementia. Measurements All research participants undergo multiple assessments to fully characterise the biology of Alzheimer’s disease and relate this to risk factors (both fixed and modifiable) and biomarker expression of disease through brain imaging, fluid samples (CSF, blood, urine and saliva), cognitive performance, functional abilities and neuropsychiatric symptomatology. Results V500.0 represents the first 500 research participants baselined into EPAD LCS. The mean age was 66.4 (SD=6.7) and 47.8% were male. The data was split for presentation into 4 groups: [1] CDR=0 and Amyloid + (preclinical AD), [2] CDR=0 and Amyloid −, [3] CDR=0.5 and Amyloid + (prodromal AD) and [4] CDR=0.5 and Amyloid −. Conclusions The EPAD LCS is achieving its primary objective of trial readiness and the structured approach to data release as manifest by this first data release of V500.0 will assist researchers to describe and compare their findings as well as in systematic reviews and meta-analyses. It is anticipated given current recruitment rates that V1500.0 data release will take place in Autumn 2019. V500.1 (when the 1 year follow up is completed on the V500.0 (sub)cohort will be in Autumn 2019 also.
What are the specific biomarkers of liver disease that MRE is uniquely suited to provide for clinical trials in NASH ?

NASH is typically described in histologic terms: increased fat in hepatocytes, inflammatory activity, cellular injury, and development of fibrosis. Among these processes, fibrosis is most strongly associated with mortality. Currently, the most important biomarker provided by MRE is liver stiffness, which in engineering terms is known as the magnitude of the complex shear modulus. One of the reasons why this biomarker is so useful is that it is profoundly affected by fibrosis. In advanced fibrosis, liver stiffness is increased many-fold compared with that of normal liver tissue. Multiple studies have shown that stiffness measurement by MRE has high diagnostic performance in non-invasively detecting and staging liver fibrosis(1). The performance of MRE is probably equal to or better than biopsy in this regard due to the much larger volume of liver evaluated.
Environmental variability , succession and invasion

Spatial vs. Temporal environmental variability Environmental conditions can vary in both time and space. For example rainfall and temperatures change between years (Figure 1). Also, the environment is never even in space, some locations within an area (a whole water catchment, a forest patch, the bottom of a valley.) may have richer or wetter soils, more shade, different fire history etc. Such variable conditions will affect organism growth rates, food supply for animals, survival probabilities etc.
VIREO-EURECOM @ TRECVID 2019: Ad-hoc Video Search (AVS)

In this paper, we describe the systems developed for Ad-hoc Video Search (AVS) task at TRECVID 2019[1] and the achieved results. Ad-Hoc Video Search (AVS): We merge three video search systems for AVS, including: two concept-based video search systems which analyse the query using linguistic approaches then select and fuse the concepts, and a video retrieval model which learns the joint embedding space of the textual queries and the videos for matching. With this setting, we plan to analyze the advantages and shortcomings of these video search approaches. We submit totally seven runs consisting four automatic runs, two manual runs, and one novelty run. We brief our runs as follows:
Daily action dead reckoning using smartphone sensors

Pedestrian dead reckoning (PDR) is easy to introduce because it requires no equipment for the environment. PDR results can provide an atomic physical behavior such as step detection and turning in walking, however providing a lexible response to a user’s daily actions other than walking like sitting, moving in a line or standing is tough. Our research objective is to make PDR more usable in spite of these daily actions by estimating the movement situation using the same sensor information as conventional PDR. We applied a state transition in the movement situation recognition using the transition restrictions existing between the moving situations. A new method for moving context recognition using machine learning with accelerometer and gyroscope feature vectors simultaneous with PDR is proposed herein. The experiments show that, the movement situation recognition and the state transition technique are eicient for the whole dead reckoning performance. The proposed method can also be applied to improve the PDR positioning accuracy.