Miracle-dz/UniFAR-FTUs huggingface dataset:
Socio-Economic Impact of Business Establishments in Balagtas, Batangas City to the Community: Inputs to Business Plan Development

Business establishments in Balagtas, Batangas City bring a lot of benefits to the community therefore leading to the improvement of the socio-economic life of the people. However, despite the claim that these businesses definitely improve the quality of life of the people, there is a need not only to determine both the positive and impact, but should also identify means to mitigate adverse effects to balance between the economic gains and negative effects to the community. The local government therefore has the prime responsibility to implement stricter measures to balance the fast growth of business vis-a-vis the socio- economic impact to the community. Proposed measures maybe integrated in the local government's business plan for Balagtas that will promote long term sustainability.
Future Perspectives in Plant Biology Plant Immunity : It ’ s the Hormones Talking , But What Do They Say ?

Plants live in complex environments in which they intimately interact with a broad range of other organisms. Besides the plethora of deleterious interactions with pathogens and insect herbivores, relationships with beneficial microorganisms are frequent in nature as well, improving plant growth or helping the plant to overcome stress. The evolutionary arms race between plants and their enemies provided plants with a highly sophisticated defense system that, like the animal innate immune system, recognizes nonself molecules or signals from injured cells, and responds by activating an effective immune response against the invader encountered. Recent advances in plant immunity research underpin the pivotal role of cross-communicating hormones in the regulation of the plant’s defense signaling network (Spoel and Dong, 2008; Pieterse et al., 2009). Their powerful regulatory potential allows the plant to quickly adapt to its hostile environment and to utilize its resources in a cost-efficient manner. Plant enemies on the other hand, can hijack the plant’s defense signaling network for their own benefit by affecting hormone homeostasis to antagonize the host immune response (Grant and Jones, 2009). Similarly, beneficial microbes actively interfere with hormoneregulated immune responses to avoid being recognized as an alien organism (Van Wees et al., 2008). In nature, plants simultaneously or sequentially interact with multiple beneficial and antagonistic organisms with very different lifestyles. However, knowledge on how the hormone-regulated plant immune signaling network functions during multispecies interactions is still in its infancy. Bioinformatic and systems biology approaches will prove essential to crack this tough nut.
Self-control and implicit drinking identity as predictors of alcohol consumption, problems, and cravings.

OBJECTIVE We investigated trait and alcohol-specific self-control as unique predictors and moderators of the relation between implicit drinking identity associations and drinking. METHOD Three hundred undergraduates completed a drinking identity Implicit Association Test (IAT), trait and alcohol self-control questionnaires, and alcohol consumption, problems, and cravings inventories. RESULTS Regression analyses tested for unique effects of predictors and for Self-Control × IAT interactions. Each predictor accounted for unique variance in consumption, but there was no evidence of moderation effects. Both types of self-control, but not IAT scores, accounted for unique variance in problems. A Trait Self-Control × Implicit Drinking interaction accounted for excess zeros in problems, with a greater likelihood of not having alcohol problems among individuals with low implicit identity who had higher versus lower trait self-control. Each predictor accounted for unique variance in cravings. A Trait Self-Control × IAT interaction was also found, indicating that implicit drinking identity was a stronger predictor of cravings among those with lower versus higher trait self-control. CONCLUSIONS Results are partially consistent with previous research: Both types of self-control and drinking identity associations predicted unique variance in drinking, and moderation effects were observed for trait self-control and drinking identity associations and two of the three drinking variables. Findings suggest that trait and alcohol-specific self-control and implicit drinking identity could be useful intervention targets.
Increased frequency of hippocampal sclerosis ILAE type 2 in patients with mesial temporal lobe epilepsy with normal episodic memory.

Sir, We read with interest the study of Coras et al. (2014) reporting the absence of verbal anterograde episodic memory (AEM) impairment in patients with mesial temporal lobe epilepsy (MTLE) with a hippocampal sclerosis ILAE type 2 classification (HS ILAE 2, i.e. CA1 predominant cell loss). This finding may provide an anatomical basis for the dissociation of anterograde/long-term episodic memory seen in some disorders like accelerated long-term forgetting (Butler et al. , 2007), which has not been explained …
Increased liver stiffness in alcoholic liver disease: differentiating fibrosis from steatohepatitis.

AIM To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS). METHODS We first performed sequential LS analysis before and after normalization of serum transaminases in a learning cohort of 50 patients with ALD admitted for alcohol detoxification. LS decreased in almost all patients within a mean observation interval of 5.3 d. Six patients (12%) would have been misdiagnosed with F3 and F4 fibrosis but LS decreased below critical cut-off values of 8 and 12.5 kPa after normalization of transaminases. RESULTS Of the serum transaminases, the decrease in LS correlated best with the decrease in glutamic oxaloacetic transaminase (GOT). No significant changes in LS were observed below GOT levels of 100 U/L. After establishing the association between LS and GOT levels, we applied the rule of GOT < 100 U/L for reliable LS assessment in a second validation cohort of 101 patients with histologically confirmed ALD. By excluding those patients with GOT > 100 U/L at the time of LS assessment from this cohort, the area under the receiver operating characteristic (AUROC) for cirrhosis detection by FS improved from 0.921 to 0.945 while specificity increased from 80% to 90% at a sensitivity of 96%. A similar AUROC could be obtained for lower F3 fibrosis stage if LS measurements were restricted to patients with GOT < 50 U/L. Histological grading of inflammation did not further improve the diagnostic accuracy of LS. CONCLUSION Coexisting steatohepatitis markedly increases LS in patients with ALD independent of fibrosis stage. Postponing cirrhosis assessment by FS during alcohol withdrawal until GOT decreases to < 100 U/mL significantly improves the diagnostic accuracy.
Using Technology to Increase Feedback When Grading Assignments

Students often find that they receive little guidance as to the kinds of errors they have made and how these errors should be corrected because the pressures of modern academic life limit the time instructors have to provide feedback. Even instructors who desire to provide thorough written feedback may find it impossible due to lack of time or even the physical pain from repetitive stress. A system utilizing bar codes for providing extensive written feedback in a limited time is described in this article. Specific examples of feedback on written case studies, selling role plays, and general communication skills are provided.
Arctan power frequency droop for power electronics dominated microgrids

The microgrid is an environment constructed with the aim of controlling local distributed resources. The most common power flow control technique utilised inside a power electronics dominated or standalone microgrid is- a technique known as power frequency droop. This paper develops a novel droop controller based on an arctan power profile that can provide natural limiting of frequency deviations and accurate frequency output. The new control system has been simulated in SABER and results are presented that show the advantages of the control. A low voltage microgrid consisting of two inverters and a passive load has been constructed. Experimental results from the hardware system are presented to confirm the operation of the new droop controller.
Word-frequency effect and response bias.

Many recent investigators have studied "Response Bias" theories of the perception of common vs. uncommon words. 4 different classes of theory are distinguished, and it is demonstrated that 3 of them are inconsistent with previously published and with fresh data. The 4th sense of response bias, however, leads to the prediction that bias on correct responses may be greater than that on errors, and is very accurately consistent with the data. This is the sense of response bias as analogous to the bias of a criterion in a statistical decision.
CD 1 d-Restricted Natural Killer T Cells

Natural killer T (NKT) cells that express the semi-invariant T-cell receptor are innate-like lymphocytes whose functions are controlled by self and foreign glycolipid ligands. Such ligands are presented by the antigen-presenting, MHC class I-like molecule CD1d, which belongs to a family of lipid antigen-presenting molecules collectively called CD1. Activation of NKT cells in vivo results in rapid release of copious amounts of effector cytokines and chemokines with which they regulate innate and adaptive immune responses to pathogens, certain types of cancers and self-antigens. The nature of CD1d-restricted ligands, the manners in which they are recognised and the unique effector functions of NKT cells suggest an immunoregulatory role for this T-cell subset. Their ability to respond fast and our ability to steer NKT cell cytokine responses to altered lipid ligands make them an important target for vaccine design and immunotherapies against autoimmune diseases. This article summarises our current understanding of CD1d-restricted NKT cell biology and how these innate-like lymphocytes control inflammation.
Inflammatory markers, cholesterol and statins: pathophysiological role and clinical importance

Abstract Statins are one of the most important medications in cardio-vascular diseases since they block cholesterol synthesis by inhibiting the 3-hydroxy-3-methylglutaryl coenzyme A reductase and thus reduce low density lipoprotein concentrations. In the last years, numerous pleiotropic properties of statins have been described, beyond their well-known lipid lowering function. In particular, they are able to modulate inflammation, which plays a pivotal role in the atherosclerotic process. Several trials have shown a direct correlation between statin therapy and lower C-reactive protein concentrations. Moreover, a large body of pathophysiological studies has demonstrated that statins lower cytokine concentrations and inhibit recruitment, migration and cell adhesion to endothelium by attenuating chemokine production. They also inhibit inflammatory pathways regulated by proteins as Ras and Rho, and increase nitric oxide production which exerts a protective effect on endothelium. In addition to reducing inflammation in coronary atherosclerosis, statins also have beneficial effects in chronic inflammatory and autoimmune diseases, such as psoriasis, and they could induce clinical improvement. Statins seem to exert benefits even in settings of infection. These results suggest that initiating and monitoring statin therapy on the basis of inflammatory markers, in particular C-reactive protein, may improve cardiovascular prevention and treatment. Clin Chem Lab Med 2010;48:1685–91.
Interdialytic blood pressure obtained by ambulatory blood pressure measurement and left ventricular structure in hypertensive hemodialysis patients

Unlike in subjects with normal renal function, the relationship between hypertension and cardiovascular morbidity and mortality in dialysis patients is still being debated. In order to clarify this issue, we performed 44‐hour ambulatory blood pressure measurements (ABPM) during the interdialytic period in a group of 164 hypertensive patients, the blood pressure (BP) control based on conventional antihypertensive strategy previously, on chronic hemodialysis treatment in the Mediterranean region of Turkey. These results were then compared with their echocardiographic data. This is a cross‐sectional analysis. The mean ABPM during 44 hours was close to the manually measured predialysis value, but there was a gradual increase in the ABPM values in the interdialytic period. When divided into a group with mild or no left ventricular hypertrophy (LVH) (45 patients) and severe LVH (119 patients), the latter had significantly higher BP levels in all separate periods, while the difference in predialysis BP was not significant. Patients with severe LVH had larger left atrium and left ventricular diameters, and consumed more antihypertensive drugs. Systolic BP during the night before dialysis showed the strongest relation to LVH, but interdialytic weight gain was also independently related to LVH. Yet, 56% of the patients with systolic BP <135 had severe LVH. There is not only an association between BP and presence of LVH, but it is shown that volume expansion is also an important independent determinant of LVH. This may explain the difficulty in identifying hypertension as a cardiac risk factor in these patients.
Mathematical Modeling and Analysis A Cell Based Model of Tumor Induced Angiogenesis

Tumor-induced angiogenesis is the formation of new blood vessels from existing vasculature in response to chemical signals from a tumor. This process marks the pivotal transition from avascular to vascular tumor growth, a progressive stage of cancer beyond which cancer becomes extremely difficult to treat and survival rates decrease. The result of this research is the first cell-based model of tumor-induced angiogenesis. Existing models of tumor associated angiogenesis are at best able to reproduce realistic vascular patterns on a macroscopic scale, but because they describe cell densities, they are unable to capture the fine scales of capillary development and morphology. Our model is structured in terms of the dynamics occurring at the extracellular and intercellular levels. At the extracellular level, a partial differential equation describes diffusion, uptake, and half-life decay of tumor-secreted pro-angiogenic factor (VEGF). At the cellular level, the cellular Potts model is used to describe cell migration, growth, proliferation or cell division, cellular adhesion, and the evolving structure of the tissue. A complete description of the model and our results is available in [1]. This model provides a quantitative framework to test hypotheses on the biochemical and biomechanical mechanisms that cause tumor-induced angiogenesis.
Medicaid reimbursement of primary care providers for treatment of substance use disorders

For purposes of this paper, primary care is defined as "the provision of integrated, accessible health care services by clinicians who are accountable for addressing a large majority of personal health care needs, developing a sustained partnership with patients, and practicing in the context of family and community. " According to this definition, primary care providers include physicians, nurses, psychologists, midwives, social workers, dentists, pharmacists, and allied health professionals. The definition excludes care provided by specialists and care provided in acute settings.
Challenge Infection as a Means of Determining the Rate of Disease Resistant Trichomonas Gallinae-Free Birds in a Population

Trichomonas gallinae-free pigeons and mourning doves were infected with the Jones' Barn strain of T. gallinae to determine the rate of disease resistant T. gallinae-free birds in each population. Although all birds became infected 88% of the pigeons were resistant to trichomoniasis while 82% of the mourning doves were resistant. It was concluded that these birds had been previously infected and spontaneously lost their trichomonad fauna while retaining their resistance to fatal infection.
HP1 Is Distributed Within Distinct Chromatin Domains at Drosophila Telomeres

Telomeric regions in Drosophila are composed of three subdomains. A chromosome cap distinguishes the chromosome end from a DNA double-strand break; an array of retrotransposons, HeT-A, TART, and TAHRE (HTT), maintains telomere length by targeted transposition to chromosome ends; and telomere-associated sequence (TAS), which consists of a mosaic of complex repeated sequences, has been identified as a source of gene silencing. Heterochromatin protein 1 (HP1) and HP1-ORC-associated protein (HOAP) are major protein components of the telomere cap in Drosophila and are required for telomere stability. Besides the chromosome cap, HP1 is also localized along the HTT array and in TAS. Mutants for Su(var)205, the gene encoding HP1, have decreased the HP1 level in the HTT array and increased transcription of individual HeT-A elements. This suggests that HP1 levels directly affect HeT-A activity along the HTT array, although they have little or no effect on transcription of a white reporter gene in the HTT. Chromatin immunoprecipitation to identify other heterochromatic proteins indicates that TAS and the HTT array may be distinct from either heterochromatin or euchromatin.
Saline nasal irrigation: Its role as an adjunct treatment.

OBJECTIVE To review clinical evidence on the efficacy of saline nasal irrigation for treatment of sinonasal conditions and to explore its potential benefits. QUALITY OF EVIDENCE Clinical trials, reviews, and treatment guidelines discussing nasal irrigation were obtained through a MEDLINE search from January 1980 to December 2001. Most trials were small and some were not controlled; evidence, therefore, is level II, or fair. MAIN MESSAGE Flushing the nasal cavity with saline solution promotes mucociliary clearance by moisturizing the nasal cavity and by removing encrusted material. The procedure has been used safely for both adults and children, and has no documented serious adverse effects. Patients treated with nasal irrigation rely less on other medications and make fewer visits to physicians. Treatment guidelines in both Canada and the United States now advocate use of nasal irrigation for all causes of rhinosinusitis and for postoperative cleaning of the nasal cavity. CONCLUSION Nasal irrigation is a simple, inexpensive treatment that relieves the symptoms of a variety of sinus and nasal conditions, reduces use of medical resources, and could help minimize antibiotic resistance.
THE RELATIONSHIP BETWEEN CUSTOMER RELATIONSHIP MARKETING TACTICS, RELATIONSHIP QUALITY AND CUSTOMER'S LOYALTY IN MOBILE COMMUNICATION INDUSTRY

Relationship marketing, just as the name implies is simply the art of developing a personal relationship with your customers. Anyone can start a business but not everyone can build a strong customer relationship. The growing importance of relationship marketing has increased interest in the role of consumer trust and satisfaction in establishing, developing, and maintaining successful relational exchanges. There are many different relationship marketing tactics implemented for retaining customer. However, some of those tactics did not affect customer loyalty effectively, and switching behaviors frequently occur among most of targeted customers. Therefore, this study is aimed to investigate the effect and relationship of customer relationship marketing tactics on customer satisfaction, trust and customer loyalty, by focusing on mobile service providers in Vadodara, India . A cross-sectional relationship between relationship marketing tactics, relationship quality (trust and satisfaction) and customer loyalty was used. Findings - The results shows positive relationship between the variables included in the study. The findings contribute to understanding of the relationships between different elements of customer relationship marketing practices, relationship quality and customer loyalty, which provide critical implications for managers of service organizations; and highlight directions for future research.
Early life nutrition and metabolic programming

Research investigating the early programming of adult metabolic disease has in recent years provided much mechanistic insight into how the early environment impacts on long‐term health. It includes studies addressing the roles of intrauterine nutrient availability, which is determined by maternal nutrition, maternal exposure to oxygen, toxic events, and infection; the placental interface; and also the early postnatal environment. This review will explore the epidemiological evidence for programming of metabolic disease and provide an overview of the various studies using animals to model metabolic phenotypic outcome. It will also discuss evidence for the proposed molecular mechanisms and the potential for intervention.
The Effect of Trust, Perceived Risk, Perceived Benefit and Cost On Customer Online Purchase Intention (An Empirical Study At Accounting Students of Brawijaya University and Muhammadiyah University of Malang)

T he use of internet and e-commerce in Indonesia grows continuously. The Internet has changed the consumer behaviour in meeting their needs. Therefore, this study aims to examine the factors affecting customer’s online purchase intention to use e-commerce. This research is conducted at Economic and Business faculty of Brawijaya University and the University of Muhammadiyah Malang using a survey method. The independent variables of this study are trust, perceived risk, perceived benefit and cost. Purchase intention to use e- commerce in online shopping is the dependent variable. Partial Least Square (PLS) is used to test the hypothesis in First Order Construct (FOC) with the samples of 340 respondents. The results of this model analysis show that trust, perceived risk, perceived benefit has a positive effect on customer’s online purchase intention to use e-commerce. However it is found that cost negatively affects costumer’s online purchase intention to use e-commerce. Therefore, customer’s online purchase intention will determine the customer decision to conduct transaction or not. The implications of the research are relevant for management and system developers toconsider intention, trust, perceived risk, perceived benefit in applying and developing e-commerce transaction. Keywords : Trust, Perceived Risks, Perceived Benefit, cost, e-commerce
Liquid ultraviolet matrix‐assisted laser desorption/ionization – mass spectrometry for automated proteomic analysis

We have combined several key sample preparation steps for the use of a liquid matrix system to provide high analytical sensitivity in automated ultraviolet – matrix‐assisted laser desorption/ionisation – mass spectrometry (UV‐MALDI‐MS). This new sample preparation protocol employs a matrix‐mixture which is based on the glycerol matrix‐mixture described by Sze et al. (J. Am. Soc. Mass Spectrom. 1998, 9, 166–174). The low‐femtomole sensitivity that is achievable with this new preparation protocol enables proteomic analysis of protein digests comparable to solid‐state matrix systems. For automated data acquisition and analysis, the MALDI performance of this liquid matrix surpasses the conventional solid‐state MALDI matrices. Besides the inherent general advantages of liquid samples for automated sample preparation and data acquisition the use of the presented liquid matrix significantly reduces the extent of unspecific ion signals in peptide mass fingerprints compared to typically used solid matrices, such as 2,5‐dihydroxybenzoic acid (DHB) or α‐cyano‐hydroxycinnamic acid (CHCA). In particular, matrix and low‐mass ion signals and ion signals resulting from cation adduct formation are dramatically reduced. Consequently, the confidence level of protein identification by peptide mass mapping of in‐solution and in‐gel digests is generally higher.