Miracle-dz/UniFAR-FTUs huggingface dataset:
Caractérisation de facteurs bactériens essentiels à la virulence des souches de Escherichia coli associées à la maladie de Crohn

La maladie de Crohn (MC) est une affection inflammatoire chronique du tube digestif dont l'etiologie est multifactorielle. Les lesions ileales des patients atteints de MC sont anormalement colonisees par des souches pathogenes de Escherichia coli appartenant au pathovar AIEC («Adherent-Invasive E. coli»). Ces souches sont capables d'adherer et d'envahir les cellules epitheliales intestinales, et ont la capacite de survivre et de se multiplier fortement en macrophages en induisant une synthese intense de TNF-α. L'objectif de ce travail s'inscrit dans la comprehension des mecanismes permettant aux bacteries AIEC de coloniser la muqueuse intestinale et d'induire les stades precoces de la pathologie. Une precedente etude menee au laboratoire avait permis de mettre en evidence l'importance de l'activation de la voie de regulation dependante du facteur bacterien sigma alternatif RpoE (ou σE) dans le processus d'adhesion et d'invasion des cellules epitheliales intestinales par la souche AIEC de reference LF82 via l'expression des pili de type 1 et des flagelles. En continuite de ces travaux, nous montrons que l'activation de la voie de signalisation dependante du facteur σE est egalement primordiale pour la capacite des souches AIEC a former des biofilms, et une analyse bioinformatique ayant pour but d'identifier les genes regules par σE a montre que l’operon waaWVL, implique dans la biosynthese du lipopolysaccharide, est primordial pour la formation de biofilm par les souches AIEC. De plus, nous avons mis en evidence que les long polar fimbriae (LPF) sont impliques dans le ciblage de l'epithelium associe aux plaques de Peyer par les bacteries AIEC, et ceci en leur permettant de cibler specifiquement les cellules M. L'inactivation du gene Nod2, gene de susceptibilite a la MC, conduit a une augmentation du nombre de plaques de Peyer ainsi que des cellules M a leur surface, indiquant que les bacteries AIEC pourraient tirer avantage d'une susceptibilite genetique pour cibler les plaques de Peyer.
Role of industry 4.0 in process strategy

As know Germany is one of the country who introducing the industry 4.0. from this paper, it discussing the relation of process strategy in Industry 4.0. In design process, nine technology introduce by 4.0 helping in increase product of manufacture, economy of shift, industrial growth of foster, and increase the company production. This article created in hope the worker in industrial also student can know more about new technologies existing in industrial world and make improvement in future.
COMPARATIVE EFFECTS OF MINT, SAGE, THYME AND FLAVOMYCIN IN WHEAT-BASED BROILER DIETS

This study was conducted to compare the effects of mint, sage, thyme and flavomycin in wheat-based (400g wheat/kg diet) enzyme supplemented broiler diets on growth performance, organ weights and some blood parameters. One hundred and five, 1-d-old male broiler chicks (Ross) was divided into five groups of 21 chicks each. The chicks were housed on a per wire-floored cage until 42 d of age. A replicate was an individual cage with one bird. The feeding regime consisted of a starter diet until 21 d of age and a finisher diet until 42 d of age. There were five treatment groups: control, flavomycin, mint powder; sage powder and thyme powder. The supplements were not added to diets after 35 d of age. Birds received flavomycin diet gained more body weight and consumed more feed than birds received control diet or herbal powders supplemented diets. Birds fed flavomycin had better feed conversion ratio than birds fed mint, sage or thyme powder contained diets. The sage powder had a negative effect on feed conversion ratio of birds compared to control or flavomycin. The dietary treatments did not significant effect on the relative weights of pancreas, spleen, liver and heart. Feeding either flavomycin or herbal powders did not change the blood IgB, IgM, HGB, HCT, WBC and BA levels. However, IgC, RBC, NE, LY, MO, EO, PLT and MPV were significantly influenced by the dietary treatments. In conclusion, the three herbal powders in wheat-based had no additional effect on the growth performance of broiler chickens.
Volatile profiling and bio-efficacy of Citrus hystrix fruit peel as a seed protectant against Callosobruchus maculatus

Volatile chemical composition of the fruit peel of Citrus hystrix, its repellent activity and seed protectant ability against damage caused Callosobruchus maculatus were investigated. Repellent effect of the fruit peel was dose and time dependent, where maximum of 98% repellency was observed after only one hour of weevil exposure. C. hystrix fruit peel has the ability of significantly reducing both seed damage and weevil perforation index (31.01) and increasing percentage protectant ability (68.98) without affecting seed germination. Volatile fraction of C. hystrix fruit peel obtained from the HS-SPME medium polar fiber identified a total of 45 compounds. The major constituents were 3-Carene (18.310%), Citronellal (12.267%), D-limonene (11.538%), α-Pinene (9.244%), α-Cadinene (4.290%) and Copaene (4.290%), Linalool (4.020%), Caryophyllene (3.988%) and γ-Cadiene (3.544%), which accounted for about 71% of the total detected compounds. The results highly signify the strong seed protectant ability of C. hystrix fruit peel in controlling C. maculatus infestations.
Quality management in industry 4.0 era

In this era of technology advancement and industrial modernization, the concepts introduced by the German promised a great benefits and widely unexplored opportunities for application in industries. Industry 4.0 concept is one of the heavily discussed topics for academic researcher and practitioners. In this era of consumerism, manufacturing industries are required to manufactured products and services of the highest quality in order to retain competitiveness in the consumers market. The concepts of Smart Factory, Cyber-Physical System as well as Internet of Things and Services offers very capable opportunities and also downside challenges for quality management in manufacturing sectors. Thus, this paper present and discussed the opportunities and challenges in implementation of Industry 4.0 for quality management which triggered by a practical insight of an electronic production and service company in Austria. The findings of the recent study challenges are formed by the three key characteristics of Industry 4.0 which are horizontal, vertical and end-to-end manufacturing integration.
Implication de la chaîne α1 de laminine dans l’angiogenèse physiologique et tumorale

Les laminines, composants majeurs des lames basales, sont des heterodimeres glycosyles formes de trois chaines α, β et γ. La chaine α1 de laminine (LMα1), caracteristique du trimere LM111 est indispensable au developpement de la membrane limitante interne de la retine, sa perte de fonction et mutation impactant negativement l’angiogenese physiologique, tandis que sa surexpression stimule l’incidence de la tumorigenese colique, la maturation des vaisseaux sanguins et l’expansion des fibroblastes. La LMα1 favorise la proliferation des cellules cancereuses coliques et stimule l’expression du VEGFA, des composants de la voie Notch, de Dll4 et de ses cibles Hey1 et Hey2 dans le stroma tumoral. Inversement, la perte de fonction et la mutation de la LMα1 diminuent l’expression de Dll4, Hey1 et Hey2 dans la retine. L’action de la LMα1 sur l’expression de ces facteurs proangiogeniques est selective, car en etant une molecule chemoattractante pour les fibroblastes associes au cancer elle y stimule l’expression de VEGFA et de Dll4. Tandis que dans les cellules endotheliales, son action stimulatrice sur Dll4 s’accompagne de l’activation de la voie Notch. Chez l’homme, dans le contexte de tumorigenese colique, la LMα1 est fortement exprimee. Cette surexpression s’accompagne d’une augmentation de l’expression du VEGFA et de Dll4. A la lumiere de ces resultats, LMα1 pourrait constituer une cible potentielle dans les therapies anti-anticancereuses.
Growth responses of neotropical trees to logging gaps

Summary 1. Modelling growth strategies among tropical trees is an important objective in predicting the response of tree dynamics to selective logging and in gaining insights into the ecological processes that structure tree communities in managed tropical forests. 2. We developed a disturbance index to model the effects of distance to and area of logging gaps on stem radial growth rates. This index was tested using census data of 43 neotropical tree species, representing a variety of life-history strategies and developmental stages, from a selectively logged forest at Paracou, French Guiana. Growth strategies were analyzed in light of two indicators: the inherent species growth rate (when disturbance index is null) and the species reaction (change in growth rate) to logging gaps. 3. Across species, the predicted inherent growth rates in unlogged forest ranged from 0AE25 to 6AE47 mm year )1 , with an average growth of 2AE29 mm year )1 . Ontogenetic shifts in inherent growth rate were found in 26 of the 43 species. 4. Species growth response to logging gaps varied widely among species but was significantly positive for 27 species. The effect of ontogeny on growth response to logging was retained for 14 species, and species with inherent fast growth rate (5 mm year )1 ) responded less to logging gap disturbances than did species with slow inherent growth (1 mm year )1 ). 5. Functional traits explained 19–42% of the variation in the inherent growth rate and in species’ response across all developmental stages. Whereas maximum diameters and seed mass were strong predictors of inherent growth rate, maximum height, wood density, mode of germination and stem architecture were additionally involved in tree growth response. 6. Synthesis and applications: This study provides a necessary framework for developing predictive post-logging growth models for the thousands of species comprising tropical forests and is sufficiently general to apply to a broad range of managed tropical forests.
Cultivation of bacteria and fungi.

With knowledge of the basic concepts of medium composition and the physical conditions which may limit microbial growth, one can enhance the ability to grow bacteria and fungi in pure culture and to enrich for, isolate, and culture many microorganisms of interest from the environment. The major nutritional requirements for microbial growth that must be considered are sources of carbon; sources of energy; electron acceptors; nitrogen sources; sources of nutrients, such as sulfur, phosphate, magnesium, and calcium; vitamin requirements; and trace metal requirements. Some physiochemical factors affecting growth include temperature, pH, requirement for oxygen, and salinity. This chapter presents a recipe for a basic basal medium for cultivating microorganisms. The selection of the various components and their roles are discussed. The chapter also discusses physicochemical factors for cultivation of bacteria and fungi, the fundamentals of the culture of fungi, larger-scale culture of bacteria, and the progress in culturing the uncultured.
Bacterial Leaf Scorch of Amenity Trees a Wide-Spread Problem of Economic Significance to the Urban Forest

Bacterial leaf scorch (BLS) of amenity trees is caused by the bacterium Xylella fastidiosa, a xylem-limited pathogen that causes water stress resulting in leaf scorch, decline, and eventual death of affected trees. Recent surveys indicate that BLS is widespread throughout the eastern half of the United States. In New Jersey, BLS primarily affects red and pin oaks planted as landscape and street trees. Until recently, the disease was limited to southern and central regions of New Jersey, but is now found in communities throughout the State. We estimate that as many as 30% of oaks are affected by this disease in some municipalities. Not only is BLS considered a threat to northern red oak, the state tree of New Jersey, but it also has potential to devastate other species of oak such as pin and scarlet, as well. NA-TP-01-03
Le clonage somatique: un etat des lieux chez les bovins et les petits ruminants

Parmi les recentes biotechnologies de la reproduction chez les mammiferes d'elevage, le clonage par transfert de noyaux somatiques constitue un pas en avant depuis la naissance de la brebis Dolly. Cet article fait le point sur les resultats actuels obtenus dans le monde chez les bovins et les petits ruminants, les limites de la technique et les applications potentielles. L'efficacite globale du clonage (nombre de jeunes nes /nombre d'embryons reconstitues) reste encore faible (S a 7 %), mais elle progresse regulierement. Elle est cependant limitee par l'existence de mortalites embryonnaires et de physiopathologies foetales importantes apres transplantation des embryons clones dans des femelles porteuses. Apres leur naissance, les bovins clones font l'objet d'un programme de recherches a l'INRA pour evaluer leur sante, leurs performances a l'âge adulte ainsi que les eventuels risques associes au clonage. Malgre l'existence de differentes barrieres biologiques encore mal maitrisees, plusieurs applications du clonage peuvent etre envisagees dont la production d' animaux modeles de maladies, la contribution a la selection bovine, la reproduction de genotypes rares, ou bien, l'association avec la transgenese pour des utilisations a des fins biomedicales. Les recherches en cours prennent en compte la reflexion ethique et la perception sociale du clonage animal.
English prepositions in functional discourse grammar

Adpositions have always been problematic in terms of analysis and representation: should they be regarded as lexical elements, with an argument structure, or as semantically empty grammatical elements, i.e. as operators or functions? Or could it be that some adpositions are lexical and others grammatical, or even that one and the same adposition can be either, dependent on its use in a particular context? In Functional Grammar (Dik 1997a,b) adpositions are analysed as grammatical elements, represented as functions expressing relations between terms (referring expressions). Various alternative treatments have been proposed within FG, all of which, however, fail to solve all the problems, or address all the relevant questions involved. This article offers an analysis of English prepositions within the model of Functional Discourse Grammar (Hengeveld and Mackenzie 2006, 2008), based on the semantic, syntactic and morphological evidence available and fully exploiting the novel features of this model.
Effect of environmental temperature on lethality of endotoxin and its effect on body temperature in mice.

Abstract : Acute exposure of mice to an environmental temperature of either 5C or 37C reduced the LD50 of a crude Serratia marcescens endotoxin from a high of 2300 micrograms in mice housed at 30C to an amount less than 40 micrograms. At 15C or 32C, the LD50 was, respectively, 800 micrograms and 550 micrograms, while at 25C it was 1200 micrograms. Control animals placed at each of these temperatures were able to maintain normothermia except for those at the high and low extremes where they became slightly hyperthermic and hypothermic. Following an injection of either twice the LD50 or a dose of 1000 micrograms, the thermoregulatory ability was upset at all temperatures except 30C. Mice at temperatures below 30C became progressively more hypothermic as the environment was increasingly cold and vice versa at higher temperatures. It is believed that endotoxin sensitizes mice to heat and cold rather than these temperatures sensitizing to endotoxin. After one week of acclimatization at 5C or 237C, the LD50 of endotoxin increased, respectively, to 790 micrograms and 260 micrograms. Inducibility of the liver enzyme tryptophan pyrrolase, believed to play a role in an animal's response to endotoxin, was evaluated at each environmental temperature. Only at the extremes was it suppressed.
Crescimento e produtividade do cafeeiro sombreado e a pleno sol

Growth and productivity of coffee plants under shade and full sun Coffee is an important exporting agricultural commodity in the world and the Brazil is in a leading position as the world’s largest exporting producer. However, the product is quite vulnerable to market price floating. In that scenario, diversifying products can be an important strategy to keep the economic equilibrium of the property. The aim of this study was to evaluate the effect of different levels of solar radiation on the growth and production of coffee (Coffea arabica L.), as well as coffee quality. The research was conducted from January 2002 to August 2005 at ESALQ/USP, in Piracicaba-SP (22°42’30” S, 47°38’00” W – altitude 550 m). The experiment comprised an adult rubber tree, clone PB 235, and coffee cv Obatã IAC 1669-20, grown in January 2002 in a rubber tree understory, interfacing with rubber trees and monocrop trees (sun exposed). The treatments included a 25, 30, 35, 40, 45, 80, 90, 95, 98, 99 and 100% luminosity gradient, formed by coffee plant rows grown at different distances from the rubber trees, both within and interfacing with the rubber tree plantation and monocrop (full sun). The experimental design was that of random blocks with 11 treatments and 4 replications. The analyzed variables were those related to growth (trunk and crown diameter, initial height of canopy, plant height, total leaf area, above-ground dry mass, number of branches and nodes and internodes length, single leaf area, NAR, LAR, SLA, LAI, G and RGR,) and coffee production (productivity, yield and rate of biannual production), as well as those related to coffee quality (fruit maturity, bean size and sensorial analysis of the beverage). The coffee growth and productivity, as well as the quality, were modified by irradiance availability. The growth and the productivity increased with the solar radiation increment. The irradiance increment starting from 70% practically did not change the accumulation of the plant above-ground dry mass and under high shading the dry mass was very low. The productivity of the coffee plant chanded a little starting from 60% of radiation and the approximately 70% were stabilized. Instead, a coffee quality improvement was observed as shading was intensified, with more maturation uniformity fruit, larger grains and better quality drink.
Application of bacteriophages to control pathogenic and spoilage bacteria in food processing and distribution.

Bacteriophages biocontrol in foods has been investigated primarily in fresh produce, dairy products, and meat products, while most work with pathogenic bacteria and spoilage bacteria has focused on meat. The effect of added phages is relatively rapid, and while phages may survive on foods for some time after application and possibly during distribution, there is little biocontrol being exerted during distribution and control does not rely on phage replication to be effective. Beyond their use to control bacteria in foods directly, phages might also be used as sanitizers in food production facilities, and their activities against biofilms have received some attention. Research into phage control of spoilage bacteria has tended to focus on Pseudomonas. The pathogen E. coli O157:H7 has received comparatively little attention in terms of control by phages on produce. A conference paper described phage biocontrol on lettuce and melon. This work used a commercially available mixture of phages with incubation at 4°C. The formation of biofilms can pose significant problems to the food industry. Vibrio spp. are common in aquatic habitats and can be detected in many seafoods. Many reports describing successful biocontrol on foods use very large numbers of phages. Data have been presented illustrating a dose dependent response for the inactivation of L. monocytogenes on salmon and other foods. The data indicate that phages show promise as biocontrol agents for the control of food-borne pathogenic bacteria and spoilage bacteria, especially since their mode of action is becoming better understood.
Comparative analysis of histopathological alterations and immunohistochemistry in cattle for diagnosis of rabies

Comparative analysis of histopathological alteratio ns and immunohistochemistry was performed on 15 brain samples of cow. In the present study, brain tissues were positive in 9 cases (60.0%), using polyclonal antiserum by immunohistochemistry and 7 cases (46.60%) were found positive for rabies by demonstration of Negri bod ies. Hundred neurons per case were observed for Negri bodies; nu mber of Negri bodies in positive neurons was counte d and a comparison of IHC and histopathology was done. Number of neurons positive for rabies virus antigen per 100 neurons (900 neurons) by IHC were more (665) than H& E staining (344) and average number of Negri bodies per neuron detected by IHC were more (2.97 ) than histopathology (1.52 ), therefore, IHC was found to be more sensitive tha n histopathology.
Lessons from the west: a review of Gambusia in Western Australia

The Eastern mosquitofish (Gambusia holbrooki) was introduced into Western Australia in 1934. We discuss the various studies that have assessed the ecology and impacts of this species in the State. This includes the contemporary distribution, behavioural studies relating to its aggressive nature, studies on the biology, ecology, parasites and disease of the species.
Love Conceptualized as Mutual Communal Responsiveness

Th e term love is used in many ways. It has been used to refer to sexual feelings for another person, motivation to be with a person, and selfl ess devotion to another (just to name a few). Many times it refers to a combination of these things. Very often the term is used without defi nition. No one usage is the right one. Each has value. Yet in conducting research and in writing about love for academic purposes, it is important to make one’s own conceptual defi nition clear.
AGS volume 84 issue 1 Cover and Back matter

In this timely volume the authors provide an authoritative digest of all the available information on the mites (Acarina) known to produce injury to plants of economic importance. They review our present knowledge of the general systematics, biology, and distribution of the world's phytophagous mites, and of their biological enemies, their role in the transmission of plant diseases, and methods for their control. Modern theories concerning the factors influencing the population development of mites and their resistance to pesticides are also reviewed. The authors all world authorities have also presented hitherto unpublished information in each of their specialized fields of activity. Taxonomic keys to the economic species and a complete key to all genera of the Eriophyoidae are included. Lee R. Jeppson is a member of the Department of Entomology at the University of California, Riverside. Hartford H. Keifer recently retired as Program Supervisor of the Insect Identification Laboratory, California Department of Agriculture, Sacramento. Edward W. Baker is a research entomologist at the U.S. Department of Agriculture, Beltsville, Maryland. 528 pages £13.75