Miracle-dz/UniFAR-FTUs huggingface dataset:
Neuropeptide F receptor acts in the Drosophila prothoracic gland to regulate growth and developmental timing

As juvenile animals grow, their behaviour, physiology, and development need to be matched to environmental conditions to ensure they survive to adulthood. However, we know little about how behaviour and physiology are integrated with development to achieve this outcome. Neuropeptides are prime candidates for achieving this due to their well-known signalling functions in controlling many aspects of behaviour, physiology and development in response to environmental cues. In the growing Drosophila larva, while several neuropeptides have been shown to regulate feeding behaviour, and a handful to regulate growth, it is unclear if any of these play a global role in coordinating feeding behaviour with developmental programs. Here, we demonstrate that Neuropeptide F Receptor (NPFR), best studied as a conserved regulator of feeding behaviour from insects to mammals, also regulates development in Drosophila. Knocking down NPFR in the prothoracic gland, which produces the steroid hormone ecdysone, generates developmental delay and an extended feeding period, resulting in increased body size. We show that these effects are due to decreased ecdysone production, as these animals have reduced expression of ecdysone biosynthesis genes and lower ecdysone titres. Moreover, these phenotypes can be rescued by feeding larvae food supplemented with ecdysone. Further, we show that NPFR negatively regulates the insulin signalling pathway in the prothoracic gland to achieve these effects. Taken together, our data demonstrate that NPFR signalling plays a key role in regulating animal development and may thus play a global role in integrating feeding behaviour and development in Drosophila.
Epilepsy and its management in relation to Psychiatry

The relation between psychiatry and epilepsy remains one of the topics that have been continuously attracting attention in medical literature since the time of Hippocrates. Forced normalization was later conceptualized when biological treatment for psychiatric disorders was developed. Recently, several reports were published regarding possible adverse psychiatric effects of antiepileptic medications. The picture is further complicated by the fact that psychotropic medications, which may be used for treatment of psychiatric disorders in epilepsy, can have negative effects on seizure control. This paper aimed to review psychiatric presentations in individuals with epilepsy and the adverse psychiatric effects of antiepileptic medications. The paper also briefly discusses available treatment options with regards of better psychotropic treatment options. Recent developments in this field led to the observation that psychiatric symptoms, in relation to seizure, can be categorized into the following types pre-ictal, post-ictal, inter-ictal and ictal symptoms. Depression and anxiety are commonly associated with epilepsy and can occur as pre-ictal, ictal, post-ictal or inter-ictal symptoms. Depression can be severe and suicidal behavior has been reported as one of the common psychiatric associations with epilepsy and has also been linked to use of some antiepileptic drugs. Psychosis can occur as an acute or chronic form. Transient pleomorphic postictal psychosis particularly observed in those with hippocampal sclerosis. There is an increased risk of developing schizophrenia and schizophrenia-like psychosis in patients with epilepsy. Psychiatric symptoms can also emerge during use of some of the antiepileptic drugs. Adverse psychiatric events include depression, psychosis, suicidal risk, and cognitive impairment. Some of the psychotropic medications are known to be epileptogenic. Therefore, selection of psychotropic medications should be based on their possible effects on seizures and those known to be epileptogenic should be avoided.
The Sequelae of Silence: Catheter Entrapment as a Preventable Morbidity Resulting from Communication Failure

Medical errors follow a well-established association with communication failure. Seemingly benign interventions such as central venous catheterization can have far reaching consequences. A 72-year-old male required reoperative mitral valve replacement surgery for culture negative endocarditis. Intraoperatively, a central venous catheter was placed without communication between the surgical and anesthesia teams. Despite a seemingly uneventful operative and post-operative course, prior to discharge, the catheter was unable to be removed and necessitated surgical removal. Bidirectional communication during cardiovascular surgery is key to achieving optimum outcomes. Fortunately, it often requires many errors to lead to un- necessary morbidity, however sometimes it takes but one.
Impact of CH2018 Climate Change Scenarios for Switzerland on today’s Swiss building stock

The energy demand of buildings heavily depends on outdoor temperature. Current climate change projections suggest an increase in annual mean temperatures of up to 5.4°C for Switzerland until the end of the century. In this study, an existing bottom-up building stock model is coupled with the latest spatio-temporal climate change projections. This allows for simulating the heat demand for each Swiss building for three different climate change scenarios and three periods. It is found that while space heat demand can decrease up to 33% by the end of the century, the need for air conditioning can arise. Furthermore, the impact of climate change differs between regions in Switzerland.
Otel İşletmelerinde Mutfak Şeflerinin Yenilikçi Davranışlarını Etkileyen Faktörlerin Analizi: Antalya Örneği (Analysis of the Factors Affecitng Innovative Behaviors of Kitchen Chefs in Hotel Businesses: The Case of Antalya)

Araştırmada otel işletmelerinde çalışan mutfak şeflerinin yenilikçi davranışlarını etkileyen faktörlerin belirlenebilmesi amaçlanmaktadır. Araştırmada nicel araştırma yöntemi kullanılmıştır. Araştırma amacı doğrultusunda alanyazın taraması yapılmış ve ölçme aracı için ifade havuzu oluşturulmuştur. Uzman görüşü ve pilot çalışma sonrasında ölçme formunun son hali ile araştırma verileri 2017 yılı Temmuz-Ağustos aylarında Antalya ili Kemer, Aksu ve Serik ilçelerinde bulunan beş yıldızlı otel işletmelerinin mutfak bölümünde çalışan aşçıbaşı, aşçıbaşı yardımcısı ve bölüm şefleriyle anket tekniğiyle elde edilmiştir. Toplam 357 katılımcıdan elde edilen verilerle açımlayıcı faktör analizi gerçekleştirilmiştir. Açımlayıcı faktör analiziyle yenilikçi davranış değişkenini oluşturan “araştırma” ve “geliştirme” olmak üzere iki faktör ortaya çıkmıştır. Bu faktörler bağımlı değişken olarak belirlenen yenilikçi davranış değişkeninin faktörleridir. Yenilikçi davranış değişkenini etkilediği değerlendirilen “yönetsel uygulamalar”, “teknolojik araçlar”, “yasal düzenlemeler”, “takım çalışması”, “müşteri beklentileri” ve “yetkinlik” olmak üzere altı bağımsız faktörün oluştuğu görülmüştür. Gerçekleştirilen regresyon analizleri sonucunda; “yönetsel uygulamalar”, “teknolojik araçlar” ve “müşteri beklentileri” faktörlerinin yenilikçi davranış değişkenini anlamlı bir şekilde etkilediği görülmüştür.
Dual‐band dual‐polarized compact planar monopole antenna for wide axial ratio bandwidth application

In this article, a geometrically simple, microstrip line‐fed planar monopole structure with slanting edge ground plane is designed to realize the dual‐band dual‐polarized operation. The proposed antenna consists of a rotated U‐shaped patch and an electromagnetically coupled L‐shaped parasitic radiating element. Owing to the combination of microstrip line‐fed radiating patch and a slanting‐edge rectangular ground plane on the opposite side of the substrate, the proposed dual‐band antenna can generate broad axial ratio bandwidth (ARBW) in the upper frequency band. The overall dimension of the prototype is only 32 × 32 × 1.6 mm3. The measured results validate that the proposed antenna has two operational frequency bands, 29.84% (1.54‐2.08 GHz) for linearly polarized radiation and 71.85% (3.96‐8.4 GHz) for circularly polarized radiation. Measured result shows that 3‐dB ARBW of the proposed antenna is 73.54% (3.80‐8.22 GHz) in the higher frequency band. It shows that the higher frequency band exhibits a left‐hand circularly polarized radiation in the boresight direction.
KNOWLEDGE AND AWARENESS REGARDING ANTIBIOTIC PROPHYLAXIS FOR INFECTIVE ENDOCARDITIS AMONG UNDERGRADUATE DENTAL STUDENTS

ABSTRACT Objective: To evaluate the knowledge and awareness regarding antibiotic prophylaxis for infective endocarditis (IE) among undergraduate dental students. Methods: A validated questionnaire of 16 questions, regarding the basic knowledge and awareness about antibiotic prophylaxis for the prevention of IE, was distributed among 100 students randomly belonging to final year and internship (5 year trainee) of the undergraduate dental program in Saveetha Dental College and Hospital, Saveetha University, Chennai. The data extracted were tabulated, statistically analyzed, and results obtained. Results were calculated on the basis of frequency and percentages using SPSS Version 20.0. th Results: About 73% of the students were aware of IE prophylaxis, and 40% of dental students were exposed to treating patients susceptible to IE. 56% of participants answered that amoxicillin is the first line of antibiotic for IE prophylaxis and 59% replied 2 g PO 1 hr before the appointment is the recommended regimen. 36% said that erythromycin is no longer recommended by American Heart Association for IE prophylaxis. However, only one-third of the participants knew about the cardiac conditions and dental procedures that require antibiotic prophylaxis for the prevention of IE. Furthermore, only 16% knew about the recommended dosage of clindamycin. Conclusion: This study revealed a reasonable knowledge and awareness about IE prophylaxis among undergraduate dental students but was inadequate. Hence, this study emphasizes the need for improved education in the teaching curriculum for dental students regarding IE prophylaxis. A standard protocol regarding the training as well as preventive measures for IE should be formulated for the dental students and the knowledge acquired must be transferred into practice. Keywords: Infective endocarditis, Prophylaxis, Antibiotics, Dental students, Knowledge.
Exploring prokaryotic transcription, operon structures, rRNA maturation and modifications using Nanopore-based native RNA sequencing

The prokaryotic transcriptome is shaped by transcriptional and posttranscriptional events that define the characteristics of an RNA, including transcript boundaries, the base modification status, and processing pathways to yield mature RNAs. Currently, a combination of several specialised short-read sequencing approaches and additional biochemical experiments are required to describe all transcriptomic features. In this study, we present native RNA sequencing of bacterial (E. coli) and archaeal (H. volcanii, P. furiosus) transcriptomes employing the Oxford Nanopore sequencing technology. Based on this approach, we could address multiple transcriptomic characteristics simultaneously with single-molecule resolution. Taking advantage of long RNA reads provided by the Nanopore platform, we could (re-)annotate large transcriptional units and boundaries. Our analysis of transcription termination sites suggests that diverse termination mechanisms are in place in archaea. Moreover, we shed additional light on the poorly understood rRNA processing pathway in Archaea. One of the key features of native RNA sequencing is that RNA modifications are retained. We could confirm this ability by analysing the well-known KsgA-dependent methylation sites and mapping of N4-acetylcytosines modifications in rRNAs. Notably, we were able to follow the relative timely order of the installation of these modifications in the rRNA processing pathway.
Accounting Information Systems (AIS) in SMEs: Towards an Integrated Framework

Small-medium enterprises (SMEs) have always been considered to be the backbone of Brunei's economy. As published by the OECD in 2006, SMEs constitute a high percentage of businesses, where they account for 98% of all active business enterprises, and contribute about 92% of the employment in the private sector, and at least 66% of the GDP within the non-oil sector of the economy. Since SMEs are considered to be significant for the economy, they are encouraged to improve their business performance in order to sustain their business development by enhancing their accounting information system. This article will focus on the current accounting practices in which Brunei SMEs have been implemented by MMA Cube Stores as a case study. As cube shop businesses have been growing all over the country, it is significant to carry out this research as it may apply to the other similar business in Brunei. Reasonable recommendations are included in this article for the augmentation of the accounting system among Brunei SMEs.
Washing Away SOAP Notes: Refreshing Clinical Documentation

This article presents a new framework for documentation based on the Canadian Model of Occupational Performance and the World Health Organization's International Classification of Functioning, Disability and Health. It is the outcome of a review of occupational therapy clinical documentation in an older adult's rehabilitation setting in a New Zealand public hospital. The 'Subjective-Objective-Assessment-Plan' format was predominantly being used for note writing and focused on clients' physical skills in self-care tasks contributing to the loss of the unique nature and philosophies of occupational therapy. The new framework is now a service policy and being used by other occupational therapy services and has the potential to be used in all areas of practice.
A Multiviewpoint Outdoor Dataset for Human Action Recognition

Advancements in deep neural networks have contributed to near-perfect results for many computer vision problems, such as object recognition, face recognition, and pose estimation. However, human action recognition is still far from human-level performance. Owing to the articulated nature of the human body, it is challenging to detect an action from multiple viewpoints, particularly from an aerial viewpoint. This is further compounded by a scarcity of datasets that cover multiple viewpoints of actions. To fill this gap and enable research in wider application areas, in this article we present a multiviewpoint outdoor action recognition dataset collected from YouTube and our own drone. The dataset consists of 20 dynamic human action classes, 2324 video clips, and 503 086 frames. All videos are cropped and resized to 720 × 720 without distorting the original aspect ratio of the human subjects in videos. This dataset should be useful to many research areas, including action recognition, surveillance, and situational awareness. We evaluate the dataset with a two-stream convolutional neural network architecture coupled with a recently proposed temporal pooling scheme called kernelized rank pooling that produces nonlinear feature subspace representations. The overall baseline action recognition accuracy is 74.0%.
Internal Mammary Sentinel Lymph Node Biopsy

The conception of internal mammary sentinel lymph node biopsy (IM‐SLNB) has been added to the 2009 American Joint Committee on Cancer breast cancer staging manual. However, there has still been slight variation in the surgical treatment model owing to the low visualization rate of internal mammary sentinel lymph nodes (IM‐SLN) with the traditional radiotracer injection technique. According to the hypothesis of IM‐SLN, a modified injection technique (periareolar intraparenchymal, high volume, and ultrasound guidance) was established, which could significantly improve the IM‐SLN visualization rate, and make the IM‐SLNB procedure possible in routine practice. IM‐ SLNB could provide minimally invasive staging, prognosis, and decision‐making individually, especially for the patients with clinically positive axilla lymph nodes. Moreover, radiotherapy targeting on internal mammary lymph nodes (IMLN) should be tailored and balanced between the potential benefit and toxicity, and radiotherapy guided by IM‐SLNB could achieve this goal. In the era of emphasizing the effective adjuvant therapy, within the changing therapy approach—more systemic treatment, less loco‐regional treatment—oncologist should reconsider the application of regional IMLN therapy.
Activity niches outperform thermal physiological limits in predicting global ant distributions

Thermal physiology is commonly used in mechanistic models to predict species distribution and project distribution change. Such thermal constraints for ants are often measured under laboratory conditions as critical thermal limits (CTmax and CTmin), but have also been observed in the field as foraging thermal limits (FTmin and FTmax). Here we compared distribution projections based on ant physiological and behavioural thermal limits with their realized distributions to assess the validity of using ecophysiological models to predict species ranges over large scales.
Perspectivas estudiantiles sobre actividades de instrucción entre pares desarrolladas en un curso de mecánica introductoria

En el marco de un proyecto de investigacion en educacion en Fisica se estan estudiando los beneficios, para el aprendizaje, derivados de la implementacion de la modalidad didactica denominada Instruccion entre Pares en un curso introductorio de Mecanica de nivel universitario. En el contexto de esta metodologia de aprendizaje activo, los conceptos y relaciones se abordan a traves de preguntas conceptuales, cuyas respuestas involucran instancias de aprendizaje colaborativo. En este trabajo presentamos los resultados obtenidos a partir de una encuesta disenada para evaluar las perspectivas de estudiantes que ya habian terminado un primer curso de Mecanica en el que se implemento dicha metodologia. Las valoraciones positivas de ellos con respecto a las clases en las que se aplico la Instruccion entre Pares nos alientan a continuar implementandola.
Comparative Study of Laparoscopic Versus Open Resection of Colorectal Liver Metastasis

C l i n M e d International Library Citation: Petersen CH, Larsen PN, Storkholm J, Schultz NA, Jensen KH (2016) Comparative Study of Laparoscopic Versus Open Resection of Colorectal Liver Metastasis. Int J Surg Res Pract 3:040 Received: September 12, 2015: Accepted: March 28, 2016: Published: March 30, 2016 Copyright: © 2016 Petersen CH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Petersen et al. Int J Surg Res Pract 2016, 3:040
The mismeasure of nature: the political ecology of economic valuation of Tiger Reserves in India

The Indian state has conserved tigers by establishing reserves that are governed as a form of fortress conservation. Residence and local uses in these tiger reserves are often criminalized. It is in this context that we critique recent neoliberal attempts to estimate the economic value of ecosystem services from tiger reserves. Proponents of valuation argue that it will not only provide a justification for the reserves, but also recognize the importance of ecosystem services for human well-being. We use a political ecology approach to argue that economic valuation is never a benign tool, but is situated in wider institutional contexts that favor certain actors over others. In India, protected areas are being valued even as people living within them are being evicted and their use of the forest restricted. We draw from fieldwork in the Biligiri Rangaswamy Temple Hills of Karnataka and conversations with Soligas. We ask how nature is made legible and who benefits from such legibility? We suggest that economic valuation can hide complex human-nature relationships and undermine different ways of knowing and 'valuing' landscapes. Key Words : tiger reserves, Karnataka, economic valuation
COMPACT DIRECTIONAL COUPLED-LINE COUPLER WITH INDEPENDENT POWER DIVISION RATIOS AT DUAL BANDS

This paper presents the first coupled-line coupler that provides independent power division ratios at dual bands. In contrast with previous dual-band coupled-line couplers, the power division ratios k(f1) and k (f2) at each band (f1 and f2) can be independently controlled in order to satisfy the requirements of various communication protocols at different bands. Moreover, it has a compact size due to the usage of coupled lines rather than transmission lines. Explicit design equations and design guide of the coupler are provided. In this letter, one prototype of the proposed coupler is simulated, fabricated, and measured. It provides power division ratios k(f1) = 4dB at f1 = 1GHz and k (f2) = 8 dB at f2 = 2.4GHz. The measured result agrees well with the simulation.
Haemodynamics and vascular remodeling in vascular access : insights from numerical studies

• A submitted manuscript is the author's version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers.
The ability of dryland farmer households in achieving food security in food-insecure area of east nusa tenggara, Indonesia

Dryland farmer households in food-insecure areas are faced with an unfavorable situation infertile agricultural land, low rainfall, lack of production activity and very limited infrastructure. On the other hand, their needs for food consumption must be fulfilled for a healthy, productive and sustainable life. The purpose of this study is to determine the ability of farmer households to achieve food security in food-insecure areas. This study uses primary data obtained from dryland farmer households by snowball sampling. The ability of dryland farmer households in terms of food availability, access to food, food utilization, energy adequacy rate, protein adequacy rate, the ratio of food expenditure and total expenditure. The households commonly consume local food with the amount of energy and protein sufficiency less than the recommended amount. The food consumption adaptation strategy is applied during the off-season and/or when food stock is running low.
A Wi-Fi FTM-Based Indoor Positioning Method with LOS/NLOS Identification

In recent years, many new technologies have been used in indoor positioning. In 2016, IEEE 802.11-2016 created a Wi-Fi fine timing measurement (FTM) protocol, making Wi-Fi ranging more robust and accurate, and providing meter-level positioning accuracy. However, the accuracy of positioning methods based on the new ranging technology is influenced by non-line-of-sight (NLOS) errors. To enhance the accuracy, a positioning method with LOS (line-of-sight)/NLOS identification is proposed in this paper. A Gaussian model has been established to identify NLOS signals. After identifying and discarding NLOS signals, the least square (LS) algorithm is used to calculate the location. The results of the numerical experiments indicate that our algorithm can identify and discard NLOS signals with a precision of 83.01% and a recall of 74.97%. Moreover, compared with the traditional algorithms, by all ranging results, the proposed method features more accurate and stable results for indoor positioning.