Miracle-dz/UniFAR-FTUs huggingface dataset:
UAVs for smart cities: Opportunities and challenges

This paper discusses the applications of unmanned aerial vehicles (UAVs) in smart cities, their opportunities and their challenges. UAVs have a wide range of applications in many fields like environmental hazards monitoring, traffic management and pollution monitoring, all of which contributes greatly to the development of any smart city. These opportunities among several others are discussed in this paper. Several challenges and issues such as safety, privacy and ethical uses are of great concern and are also provided in this paper.
Superfícies seletivas em frequência: análise e projeto

Este livro apresenta uma analise teorica para a obtencao de resultados numericos, das caracteristicas de espalhamento, de superficies seletivas em frequencia compostas por arranjos periodicos de elementos do tipo patch perfeitamente condutor. Tecnicas de analise aproximadas e de onda completa sao consideradas. A analise de onda completa e efetuada utilizando-se o metodo da linha de transmissao equivalente em combinacao com o metodo de Galerkin. Nas analises, sao consideradas diferentes geometrias de patches. Sao analisadas estruturas com dieletricos isotropicos e anisotropicos, com anisotropia uniaxial. Sao efetuadas comparacoes com resultados teoricos e experimentais apresentados na literatura e obtidos pelo autor. Rotinas computacionais, utilizadas nas analises apresentadas, elaboradas no programa computacional Matlab©, sao fornecidas no final de alguns capitulos.
Molecular Basis for ADP-induced Platelet Activation

ADP is an important platelet agonist causing shape change from smooth discoid shape to spiculated spheres and platelet aggregation. However, the molecular mechanisms involved in ADP-induced platelet activation have not been elucidated. We demonstrated earlier the existence of two distinct ADP receptors on platelets, one coupled to phospholipase C, P2TPLC, and the other to inhibition of adenylyl cyclase, P2TAC (Daniel, J. L., Dangelmaier, C., Jin, J., Ashby, B., Smith, J. B., and Kunapuli, S. P. (1998)J. Biol. Chem. 273, 2024–2029), in addition to the previously described P2X1 receptor. Here we report the cloning of a cDNA clone encoding the P2Y1 receptor from a human platelet cDNA library by homology screening with radiolabeled P2Y1-P2Y6 receptor cDNAs. ADP or 2-methyl(thio)-ADP-induced intracellular calcium increases were inhibited by the P2Y1 receptor-specific antagonists, adenosine 3′-phosphate 5′-phosphosulfate (A3P5PS), adenosine 3′-phosphate 5′-phosphate (A3P5P), and adenosine 2′-phosphate 5′-phosphate (A2P5P), in a concentration-dependent manner, but not by ARL 66096 or α,β-MeATP. A3P5PS, A3P5P, and A2P5P also inhibited the shape change of aspirinated platelets induced by 10 μm ADP or 3 μm 2-methyl(thio)-ADP in a concentration-dependent manner, with complete inhibition occurring at 300 μm. On the other hand ARL 66096 (100 nm), a potent P2TAC antagonist and α,β-methylene-ATP (40 μm), a P2X1 receptor agonist, had no effect on ADP-induced platelet shape change. On the contrary, ADP-induced inhibition of adenylyl cyclase was blocked by ARL 66096, but not by α,β-MeATP or the P2Y1 receptor-specific antagonists, A3P5PS, A3P5P, or A2P5P. These results demonstrate the role of the P2Y1 receptor in ADP-induced platelet shape change and calcium mobilization and support the idea that several P2 receptors are involved in the regulation of different aspects of platelet stimulus-response coupling.
Derivation and analysis of fragment libraries of protein structures

Fragment assembly is attracting intense research interest as a means of predicting protein structure from sequences. Success requires a good library of local structures (i.e. fragments) to serve as building blocks for whole protein reconstruction. Here, we describe a novel two-stage clustering scheme for identifying recurrent local structures and deriving fragment libraries. Parameters that represent cluster compactness, distinctiveness, and coverage were used for evaluating library quality. According to test results, our system was capable of approximating protein structures with smaller library sets at a level of accuracy comparable to or better than methods previously reported by others.
Automatic sequences. Theory, applications, generalizations

What do you do to start reading automatic sequences theory applications generalizations? Searching the book that you love to read first or find an interesting book that will make you want to read? Everybody has difference with their reason of reading a book. Actuary, reading habit must be from earlier. Many people may be love to read, but not a book. It's not fault. Someone will be bored to open the thick book with small words to read. In more, this is the real condition. So do happen probably with this automatic sequences theory applications generalizations.
The theory of critical distances applied to problems in fracture and fatigue of bone

The theory of critical distances (TCD) has been applied to predict notch-based fracture and fatigue in a wide range of materials and components. The present paper describes a series of projects in which we applied this approach to human bone. Using experimental data from the literature, combined with finite element analysis, we showed that the TCD was able to predict the effect of notches and holes on the strength of bone failing in brittle fracture due to monotonic loading, in different loading regimes. Bone also displays short crack effects, leading to R-curve data for both fracture toughness and fatigue crack propagation thresholds; we showed that the TCD could predict this data. This analysis raised a number of questions for discussion, such as the significance of the L value itself in this and other materials. Finally, we applied the TCD to a practical problem in orthopaedic surgery: the management of bone defects, showing that predictions could be made which would enable surgeons to decide on whether a bone graft material would be needed to repair a defect, and to specify what mechanical properties this material should have.
EFFECT OF ACTIVATION ON NEUTROPHIL‐INDUCED HEPATIC MICROVASCULAR INJURY IN ISOLATED RAT LIVER

Polymorphonuclear neutrophils (PMNs) have been implicated in microvascular injury following ischemia and reperfusion (I/R) but the relative contribution of obstruction versus toxic mediators is not well defined. Therefore, the present study was performed to determine the contribution of exogenous or endogenous activation on PMN-induced microvascular and hepatocyte injury. Rat livers were isolated and perfused at constant pressure with Krebs buffer with red cells (Hct-10%) and monitored for perfused sinusoids (PS) and dead hepatocytes (propidium iodide-stained, DH) by intravital microscopy. PMNs isolated from the peritoneum after oyster glycogen injection were added to the perfusate either without or with activation by phorbol myristate acetate (PMA, 160 nM). Unactivated PMNs stuck in the liver but had no significant effect on either perfused sinusoids (11.1 ± .4/field, unactivated PMNs versus 11.9 ± .5/field, the time-matched control) or dead hepatocytes (1.2 ± .4/field, unactivated PMNs versus 1 ± .3/field, the time-matched control). Infusion of PMA-activated PMNs resulted in significant decrease in perfused sinusoids and increase in DH (9.5 ± .3/field for PS and 3.2 ± .6/field for DH, respectively). In contrast, when PMNs were “activated” by infusion into a liver previously made ischemic for 30 min, DH were significantly increased after 60 min (26.2 ± 4.5/field, I/R plus PMNs versus 12.4 ± 2/field, I/R only) but perfused sinusoids were not different from ischemia alone. These results demonstrate that oxidatively quiescent PMNs do not cause cellular or microvascular injury in spite of microvascular accumulation. Activated PMNs damage microcirculation or hepatocytes depending on the nature of the activation.
Storyboarding for meetro: A smart navigation application system for commuter line in Jabodetabek

Transportation has been long part of people life, especially for the urban. The transportation need not only applied for the local, Jakarta as a capital city must be full of foreigner either for business purpose or others, and they are need a public transportation as well. Commuter Line Jabodetabek is the most preferable public transportation to avoid Jakarta's traffic. The idea is to create a mobile application system which could easily help Commuter Line Jabodetabek user to get the information about timetable schedule, arrange the route and transit information and find how to reach the destination as well as how long to get there and how much does it cost, and visualize the route in easy-to-understand format. The application system is analyzed and designed with mobile application development approach and the application development with cloud computing provided by Application Craft, and the result of this study is prototype application design with cross-platform based.
Change of Government: One More Big Bang Health Care Reform in England's National Health Service

Once again the National Health Service (NHS) in England is undergoing major reform, following the election of a new coalition government keen to reduce the role of the state and cut back on big government. The NHS has been undergoing continuous reform since the 1980s. Yet, despite the significant transaction costs incurred, there is no evidence that the claimed benefits have been achieved. Many of the same problems endure. The reforms follow the direction of change laid down by the last Conservative government in the early 1990s, which the recent Labour government did not overturn despite a commitment to do so. Indeed, under Labour, the NHS was subjected to further market-style changes that have paved the way for the latest round of reform. The article considers the appeal of big bang reform, questions its purpose and value, and critically appraises the nature and extent of the proposed changes in this latest round of reform. It warns that the NHS in its current form may not survive the changes, as they open the way to privatization and a weakening of its public service ethos.
Acceleration of AES encryption on CUDA GPU

GPU exhibits the capability for applications with a high level of parallelism despite its low cost. The support of integer and logical instructions by the latest generation of GPUs enables us to implement cipher algorithms more easily. However, decisions such as parallel processing granularity and memory allocation impose a heavy burden on programmers. Therefore, this paper presents results of several experiments that were conducted to elucidate the relation between memory allocation styles of variables of AES and granularity as the parallelism exploited from AES encoding processes using CUDA with an NVIDIA GeForce GTX285 (Nvidia Corp.). Results of these experiments showed that the 16 bytes/thread granularity had the highest performance. It achieved approximately 35 Gbps throughput. It also exhibited differences of memory allocation and granularity effects around 2%â€“30% for performance in standard implementation. It shows that the decision of granularity and memory allocation is the most important factor for effective processing in AES encryption on GPU. Moreover, implementation with overlapping between processing and data transfer yielded 22.5 Gbps throughput including the data transfer time.
Hybrid WSN-RFID cooperative positioning based on extended kalman filter

In this paper we propose a novel hybrid and cooperative positioning approach based on extended Kalman filter (EKF) to localize mobile targets in indoors. The algorithm fuses both received signal strength (RSS) measurements performed by nodes of a wireless sensor network (WSN) and proximity information from radio frequency identification (RFID) devices. Simulation results prove that the proposed cooperative approach outperforms the non-cooperative version of the algorithm.
An empirical study on the effect of corporate image upon corporate attractiveness for talents in China

Human resources is the key factor for corporate competitive advantage, so attracting and retaining excellent talents is vital to obtain competitive advantage for any enterprise. Due to the strategic role of the corporate image, some organizations are looking for new ways to consummate corporate image so as to acquire more excellent talents to enhance competitive advantage. However, in the era of knowledge based economy demands more high-level talents, which leads to freer talent flow. Then the issue of how corporate image could influence the corporate attractiveness for talents is a tough task, which should be studied theoretically and practically. This paper examined the influence of the corporate image on the corporate attractiveness for talents in Chinese labor market. We began by providing a concept model and present some hypotheses, then dimensional compositions of the corporate image in the opinion of Chinese young educated public was proceeding, and the investigation was performed among the postgraduates of business major in China. Two kinds of corporate image (background corporate image and decisive corporate image) were taken into the model that used for estimating the influence of corporate image on the corporate attractiveness for talents. So the test model will be modified according to the actual situation in China. Our results showed that corporate image had a significant positive effect on the corporate attractiveness for talents under the intermediaries of information exposure and individual cognition in Chinese labor market. Accordingly, we provide some managerial suggestions.
Current Concepts and Practice in Postoperative Pain Management:Need for a Change?

Despite a growing trend in acute pain management, many deficiencies still account for the high incidence of moderate to severe postoperative pain to date. Patients nowadays continue to receive inadequate doses of analgesics, but additionally the identification and treatment of those patients with pain still remains a significant health care problem. Advanced techniques are available including epidural or intrathecal administration of local anaesthetics and opioids, various opioid administration techniques such as patient-controlled analgesia and infusions via sublingual, oral-transmucosal, nasal, intra-articular and rectal routes. Nonopioid analgesics such as nonsteroidal anti-inflammatory drugs and newer nonopioid drugs such as α2-adrenergic agonists, calcium channel antagonists and various combinations of the above are possible. However, the solution to the problem of inadequate pain relief lies not so much in the development of new drugs and new techniques, but in the effective strategy of delivering these to patients through the introduction of acute pain management services on surgical wards.
Sexual dimorphism in gender plasticity and its consequences for breeding system evolution

SUMMARY Flowering plants are able to develop gametes throughout their lives. As a consequence, environmental conditions can impact this development and alter a plant's functional gender or the degree to which it achieves fitness through male or female function. Two dimorphic breeding systems are widespread among angiosperm families: gynodioecy (hermaphrodites and females) and dioecy (males and females). Gynodioecy can evolve into dioecy, via loss of female function on the hermaphrodites, or it can remain stable. Here I discuss how developmental plasticity of gender can impact the sex ratio of populations and thereby influence the transition of one breeding system into another. I review studies showing that greater plasticity of fruit production by hermaphrodites as compared with females causes sex ratios among populations to vary in response to environmental conditions, with higher female frequency expected in harsh or low‐quality sites. I also review how dioecy may evolve in dry sites to avoid inbreeding and any consequent inbreeding depression. Taken together, these studies show the importance of understanding how ecological development affects functional gender and consequently the evolutionary stability or malleability of dimorphic breeding systems.
Colocation of the Multiresistance Gene cfr and the Fosfomycin Resistance Gene fosD on a Novel Plasmid in Staphylococcus arlettae from a Chicken Farm

ABSTRACT The novel 63,558-bp plasmid pSA-01, which harbors nine antibiotic resistance genes, including cfr, erm(C), tet(L), erm(T), aadD, fosD, fexB, aacA-aphD, and erm(B), was characterized in Staphylococcus arlettae strain SA-01, isolated from a chicken farm in China. The colocation of cfr and fosD genes was detected for the first time in an S. arlettae plasmid. The detection of two IS431-mediated circular forms containing resistance genes in SA-01 suggested that IS431 may facilitate dissemination of antibiotic resistance genes.
A Maximum in the Strength of Nanocrystalline Copper

We used molecular dynamics simulations with system sizes up to 100 million atoms to simulate plastic deformation of nanocrystalline copper. By varying the grain size between 5 and 50 nanometers, we show that the flow stress and thus the strength exhibit a maximum at a grain size of 10 to 15 nanometers. This maximum is because of a shift in the microscopic deformation mechanism from dislocation-mediated plasticity in the coarse-grained material to grain boundary sliding in the nanocrystalline region. The simulations allow us to observe the mechanisms behind the grain-size dependence of the strength of polycrystalline metals.
Novel clearance mechanisms of platelets

Purpose of reviewBlood platelets are involved in primary and secondary hemostasis and thus maintain the integrity of the vasculature. They circulate with an average lifespan of 5–9 days in humans. Thus, the body must generate and clear platelets daily to maintain normal physiological blood platelet counts. Known platelet clearance mechanisms include antibody-mediated clearance by spleen macrophages, as in immune thrombocytopenia, and platelet consumption due to massive blood loss. Recent findingsNew concepts in the clearance mechanisms of platelets have recently emerged. New evidence shows that platelets desialyted due to chilling or sepsis are cleared in the liver by macrophages, that is Kupffer cells, as well as hepatocytes, through lectin-mediated recognition of platelet glycans. On the contrary, platelet-associated antibodies normalize the clearance of platelets in a mouse model for Wiskott–Aldrich syndrome. SummaryThe goal of this review is to summarize the latest findings in platelet clearance mechanisms with a focus on lectin-mediated recognition of platelet glycans. Transfusion medicine and treatments of hematopoietic disorders associated with severe thrombocytopenia may benefit from a better understanding of these mechanisms.
Understanding adherent cell mechanics and the influence of substrate rigidity

L’ingenierie tissulaire est une strategie medicale qui repose sur la regeneration de tissu par les cellules avec ou sans materiaux. Pour maitriser cette synthese, il faut comprendre la cellule comme une part integrante du tissu. Hormis ses interactions biochimiques avec son support, la cellule interagit egalement mecaniquement avec son environnement. Elle s’accroche a ce dernier et evalue sa durete pour adapter sa reponse biologique. Dans cette etude, j’ai developpe des modeles numeriques pour analyser l’influence de la rigidite du substrat sur le comportement mecanique de la cellule, sur sa structure contractile interne et les efforts qu’elle genere. En d’autres termes, j’ai essaye de comprendre comment la cellule ressent la rigidite de son environnement. De plus, au lieu de me focaliser sur les proprietes mecaniques quantitatives, j’ai cherche a developper un modele conceptuel simplifie plus proche de la structure cellulaire.
Dothideomycete–Plant Interactions Illuminated by Genome Sequencing and EST Analysis of the Wheat Pathogen Stagonospora nodorum[W][OA]

Stagonospora nodorum is a major necrotrophic fungal pathogen of wheat (Triticum aestivum) and a member of the Dothideomycetes, a large fungal taxon that includes many important plant pathogens affecting all major crop plant families. Here, we report the acquisition and initial analysis of a draft genome sequence for this fungus. The assembly comprises 37,164,227 bp of nuclear DNA contained in 107 scaffolds. The circular mitochondrial genome comprises 49,761 bp encoding 46 genes, including four that are intron encoded. The nuclear genome assembly contains 26 classes of repetitive DNA, comprising 4.5% of the genome. Some of the repeats show evidence of repeat-induced point mutations consistent with a frequent sexual cycle. ESTs and gene prediction models support a minimum of 10,762 nuclear genes. Extensive orthology was found between the polyketide synthase family in S. nodorum and Cochliobolus heterostrophus, suggesting an ancient origin and conserved functions for these genes. A striking feature of the gene catalog was the large number of genes predicted to encode secreted proteins; the majority has no meaningful similarity to any other known genes. It is likely that genes for host-specific toxins, in addition to ToxA, will be found among this group. ESTs obtained from axenic mycelium grown on oleate (chosen to mimic early infection) and late-stage lesions sporulating on wheat leaves were obtained. Statistical analysis shows that transcripts encoding proteins involved in protein synthesis and in the production of extracellular proteases, cellulases, and xylanases predominate in the infection library. This suggests that the fungus is dependant on the degradation of wheat macromolecular constituents to provide the carbon skeletons and energy for the synthesis of proteins and other components destined for the developing pycnidiospores.
Criteria for Involuntary Hospitalisation

Objective: The aim of this paper is to provide an overview of the ethical bases of compulsory commitment legislation. Method: The ethical principles of beneficence and autonomy are examined and used to identify criteria for the commitment of mentally ill patients. Results: Two aspects of beneficence, medical paternalism and social paternalism, are discussed. It is argued that social paternalism is insufficient ethically to warrant involuntary admission, and that the basis for compulsory hospitalisation is medical paternalism. Conclusion: The central role of autonomy in medical ethics suggests a patient should have a diminished capacity for autonomous decision-making and a potential to benefit from hospitalisation, as well as a risk of harm to self (including self-neglect) to warrant committal. In specific circumstances, the risk of harm to others may also justify committal. These ethical principles may be at odds with public attitudes.