Miracle-dz/UniFAR-FTUs huggingface dataset:
CORRECTIONS

CELL BIOLOGY Correction for “Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition,” by Donald S. Kirkpatrick, Daisy J. Bustos, Taner Dogan, Jocelyn Chan, Lilian Phu, Amy Young, Lori S. Friedman, Marcia Belvin, Qinghua Song, Corey E. Bakalarski, and Klaus P. Hoeflich, which appeared in issue 48, November 26, 2013, of Proc Natl Acad Sci USA (110:19426–19431; first published November 11, 2013; 10.1073/pnas.1309473110). The authors note that Figure 1 appeared incorrectly. The corrected figure and its legend appear below.
FODMAP-arme Diät bei Reizdarmsyndrom: Literaturübersicht und Pilotstudie über Österreich-adaptierte Diät

The low-FODMAP diet as nutritional therapy for irritable bowel syndrome: literature research and pilot-study with a diet adapted to Austrian eating habits. Background: Low-FODMAP diet is based on the concept of reducing fermentable, short-chain carbohydrates in order to alleviate unspecific gastrointestinal symptoms, primarily concerning the irritable bowel syndrome (IBS). Methods: Unsystematic literature research and a pilot study were conducted. Over the period June 2014 to October 2014 ten patients with gastrointestinal symptoms (ROME III criteria) were included in the study. The treatment consisted of a lowFODMAP diet over a period of two weeks while patients were hospitalized, and a continuation of this diet for two months on a self-reliant basis. Validated questionnaires (IBS-SSS) were used. Results: In 10 patients the severity of abdominal pain and the severity of flatulence was reduced by 85 % (p = .01) and 75 % (p = .004), respectively. Satisfaction with stool habits was improved by 43 % (p = .004). These results are significant and clinically relevant (measured on the VAS-scale). Improvement of the negative impacts of IBS on life in general did not reach statistical significance (p = .053). After two additional months of performing this diet on their own, all of the interviewed patients (n = 5) still followed the low-FODMAP diet on a daily basis. Summary: The results are comparable to the current state of relevant studies; however, there is yet a lack of randomised controlled studies. In uncontrolled studies few patients are necessary to show significant effects due to large effect sizes. The content of FODMAP is not yet known for many food items, which is why exposure limits for a lowFODMAP diet are based on experience. It seems advisable to establish the diet gradually. Conclusion: A low-FODMAP diet can reduce IBS symptoms. J Gastroenterol Hepatol Erkr 2016; 14 (1): 17–21.
BRONCHIOLITIS

Correspondence to: Dr Maud Meates-Dennis, Paediatric Department, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand; maud. meates-dennis@chmeds.ac. nz _________________________ V iral bronchiolitis is a common worldwide disease of infants and young children. It is a significant cause of hospitalisation in infancy. In the year 2002–3, 0.1% of all hospital bed days in England were for acute bronchiolitis with a mean length of stay of 2.7 days, and in a study in one UK region the incidence of bronchiolitic related admission was 30.8 per 1000 infants.
IGF-1 gene polymorphisms in Polish families with high-grade myopia

Purpose Recent work has suggested that insulin-like growth factor 1 (IGF-1) gene polymorphisms are genetically linked with high-grade myopia (HM), which is a complex-trait eye disorder in which numerous candidate loci and genes are thought to play a role. We investigated whether the IGF-1 single nucleotide polymorphisms (SNPs) rs6214, rs10860860, and rs2946834 are associated with HM (≤-6.0 diopters [D]) and any myopia (≤-0.5 D) phenotype in Polish families. Methods Forty-two multiplex HM Polish families, of whom 127 had HM, participated in the study. All of the family members (n=306) underwent a detailed ophthalmic examination, including axial length measurements. The IGF-1 SNPs rs6214, rs10860860, and rs2946834 were evaluated by PCR-RFLP and direct sequencing methods. Both Family-Based Association Test (FBAT) and family-based Pedigree Disequilibrium Test (PDT) were used to examine the potential association of the IGF-1 SNPs rs6214, rs10860860, and rs2946834 with HM or any myopia. To determine the distribution of the HM-associated SNPs rs6214 and rs10860860, 543 unrelated individuals from the general Polish population were also analyzed. Results We found no significant association between the IGF-1 SNPs rs6214, rs10860860, and rs2946834 and HM or any myopia phenotype in Polish HM families. In the general Polish population, the minor allele frequencies of the SNPs rs6214 and rs10860860 did not deviate significantly from the distribution reported for European populations (p=0.629). In the FBAT analysis under the dominant model, the haplotype consisted of T allele of rs10860860, with C allele of rs2946834 of IGF-1 was found less frequently transmitted to HM individuals (p=0.0065), pointing to a nonassociated or protective haplotype. Conclusions Our results do not support recent studies reporting an association of the SNPs rs6214, rs10860860, and rs2946834 in the IGF-1 gene with HM and any myopia phenotypes. Further replication studies involving other populations are needed to investigate the possible role of IGF-1 as a potential myopia candidate gene.
Mental Health Provider Experiences With Utilizing Evidence-Based Treatment for Post-Traumatic Stress Disorder During a Combat Deployment

ABSTRACT The present study assesses mental health care staff experiences with evidence-based treatments (EBTs) for post-traumatic stress disorder (PTSD) in a deployed environment. Mental health care providers (n = 19) and technicians (n = 20) were surveyed in Afghanistan concerning EBT delivery, attitudes, and perceived barriers to the implementation of EBTs. Relaxation techniques and supportive psychotherapy were most frequently utilized; exposure therapy techniques were least frequently utilized. Most participants had positive attitudes toward EBTs; however, providers identified unique challenges to delivering EBTs. Modular EBTs may be useful to consider to address provider concerns and improve the implementation of EBTs.
Support needs of parents of sick and/or preterm infants admitted to a neonatal unit

The sudden unexpected delivery of a preterm infant elicits many emotional responses from parents, with studies confirming the importance of providing parents with nursing support. The purpose of this study was to measure parents' perception of the type and level of support that nurses provided in an Australian neonatal unit, and to determine the extent to which parents were satisfied with the support currently provided. A convenience sample of 112 parents in an Australian tertiary neonatal unit were invited to complete the nurse parent support tool (NPST), which is a 21-item questionnaire used to measure the level of nursing support. The NPST consists of four domains -emotional, informational, appraisal and instrumental support. A second tool was used to assess parent satisfaction with nurse-to-parent support. A total of 62 parents completed the NPST and satisfaction tool. Results showed that instrumental support had the highest mean score for both nurse-to-parent support 4.51 (out of 5) and 4.36 for satisfaction. The mean score for nursing support was 4.21 followed by satisfaction with nurse-to-parent support at 4.16. In contrast, emotional support had the lowest mean score for both nurse-to-parent support at 3.94 and 3.97 for satisfaction. Parents indicated that they needed further support with lactation, breastfeeding and assistance with parenting skills. Overall, results indicated that parent perception of nursing support was positive and that parents were highly satisfied with the nursing support provided in the neonatal unit. However, some attention needs to be given to providing more support and information on breastfeeding and parenting skills.
ROLE OF GLUCOSAMINE SULPHATE ON PAIN AND TENDERNESS IN OSTEOARTHRITIS

The purpose of this study was to establish the role of Glucosamine Sulphate in reducing the common symptoms of Osteoarthritis like pain at rest, pain on movement and tenderness. 2 groups of 30 patients each were made, one of the groups received Glucosamine Sulphate therapy while the other was given placebo treatment. In the group that received Glucosamine Sulphate, there was a highly significant improvement in all the parameters at the end of therapy while there was non-significant improvement with placebo treatment. The use of Glucosamine Sulphate seems to be beneficial for the patients of Osteoarthritis.
Effects of oxygen fraction in inspired air on cardiorespiratory responses and exercise performance

Peltonen, Juha Effects of oxygen fraction in inspired air on cardiorespiratory responses and exercise performance Jyvaskyla, University of Jyvaskyla, 2002, 86 p. (Studies in Sport, Physical Education and Health, ISSN 0356-1070; 80) ISBN 951-39-1116-0 Finnish summary Diss. The present series of studies were conducted to investigate the relationship between exercise performance and oxygen uptake (V O2) by altering the fraction of oxygen in inspired air (FIO2) in an attempt to elucidate the mechanisms that regulate and limit physical work capacity. A total of 29 endurance athletes were examined in hyperoxia (FIO2 0.293 – 0.622), normoxia (FIO2 0.209) and hypoxia (FIO2 0.150-0.166). Hypoxia impaired (mean 14.7%) and hyperoxia improved (12.2%) maximal oxygen uptake (V O2max) in comparison with normoxia. Impaired V O2max was accompanied by a decrement in exercise performance (Pmax) in hypoxia (7.3%). Also, Pmax tended to be higher in hyperoxia (3.6%) than in normoxia. Thus, in both hypoxia and hyperoxia, the change in V O2max exceeded the change in Pmax. Maximal cardiac output ( Q max) was reduced (8.8%) in acute hypoxia when compared with normoxia. The reduction in V O2max in acute hypoxia is therefore explained both by the narrowing of the arterio-venous O2 difference and reduced Q max. The reduced Q max in hypoxia and the finding that hypoxia had a tendency to diminish the sum of integrated electromyography signals during maximal exercise in comparison with normoxia and hyperoxia both suggest that the central nervous system (CNS) is among those factors that limit exercise performance and V O2max in acute hypoxia. Therefore, reduced Q max and V O2max in acute hypoxia may be the result rather than the cause of reduced Pmax and skeletal muscle recruitment, which can be interpreted to support the “central governor” hypothesis. However, further studies are needed to indicate the existence and mode of action of the proposed “central governor”. This study indicates that some of those responses that previously were expected to occur only in chronic hypoxia can also be seen in acute phase, at least in highly trained endurance athletes. This study also indicates that exercise performance and V O2max may not be dependent only on the O2 delivery and utilization, but also on other factors including factors possibly linked to CNS function.
CORRECTIONS

BIOCHEMISTRY Correction for “Mechanism of ligand-gated potassium efflux in bacterial pathogens,” by Tarmo P. Roosild, Samantha Castronovo, Jess Healy, Samantha Miller, Christos Pliotas, Tim Rasmussen, Wendy Bartlett, Stuart J. Conway, and Ian R. Booth, which appeared in issue 46, November 16, 2010, of Proc Natl Acad Sci USA (107:19784–19789; first published November 1, 2010; 10.1073/ pnas.1012716107). The undersigned authors wish to note, “The KefFC system of E. coli is maintained in an inactive state by the binding of glutathione (GSH) and is activated by the formation of GSH adducts (GSX), particularly those with bulky substituents. We described two crystal structures with density present in the ligand-binding domain that we interpreted as GSH and GSX. Recently, an independent, experienced crystallographer, who had viewed the structures from our study in a different context, made representations to us that cast doubt on position of the succinimido ring of GSX. We have further reviewed the density maps with the aid of an experienced crystallographer. As a consequence, we believe it is important to draw this altered interpretation of the crystal structures to the attention of readers. In both structures, the density for the backbone of GSH is clear and allows unequivocal assignment of the position of the tripeptide. In PDB coordinate set 3L9X, the density for the succinimido ring is very weak, making interpretation very speculative and the assignment rests on the identity of the ligand added to the crystallization mixture, for which there are two diastereomers in the solution— a possibility that provides some basis for weakening the density. However, in 3L9W there are two anomalies that affect the interpretation of the bound ligand. First, there is no density for the carbon atom attached to the sulfur of GSH and second, there is extra density adjacent to the position of sulfur that could be modelled as a constrained succinimido ring. However, this density could also be water or any other molecule that is trapped in the structure. Thus, while there is good evidence for the peptide, the evidence that it is in the GSH form is uncertain. “There are no new data on either the structures or on the gating mechanism. However, we believe that we should be cautious in interpreting the structural data and that the field in general should be made aware of the alternative views of the electron density data. Note that the mutagenesis and spectroscopic data that were presented in the original manuscript are not affected by this alternative interpretation. ” Tarmo P. Roosild and Samantha Castronovo have decided not to sign this statement.
Work System Theory: An Integrated, Evolving Body of Assumptions, Concepts, Frameworks, and Principles for Analyzing and Designing Systems in Organizations

This article presents work system theory (WST) as a body of theory for analysis, explanation, prediction, and design and action (Gregor, 2006) related to systems in organizations. It provides background about how WST evolved, summarizes major components of WST, and explains that each of the five types of theory identified by Gregor (2006) appears in WST. The discussion of WST emphasizes its overall contribution to knowledge by emphasizing areas in which it differs from commonly used terminology, frameworks, and beliefs within the IS field. In a discipline in which even basic terms such as system, service, implementation, and user have many contradictory meanings, a key goal of WST is to demonstrate the possibility of using an internally consistent set of assumptions, concepts, frameworks, and principles as a basis for analysis, explanation, prediction, and design and action.
Using 3D Convolutional Neural Networks for Tactile Object Recognition with Robotic Palpation

In this paper, a novel method of active tactile perception based on 3D neural networks and a high-resolution tactile sensor installed on a robot gripper is presented. A haptic exploratory procedure based on robotic palpation is performed to get pressure images at different grasping forces that provide information not only about the external shape of the object, but also about its internal features. The gripper consists of two underactuated fingers with a tactile sensor array in the thumb. A new representation of tactile information as 3D tactile tensors is described. During a squeeze-and-release process, the pressure images read from the tactile sensor are concatenated forming a tensor that contains information about the variation of pressure matrices along with the grasping forces. These tensors are used to feed a 3D Convolutional Neural Network (3D CNN) called 3D TactNet, which is able to classify the grasped object through active interaction. Results show that 3D CNN performs better, and provide better recognition rates with a lower number of training data.
USABILITY OF INTELLIGENT AGENTSYSTEMS IN URBAN TRAFFIC CONTROL

The authors study the usefulness and application of autonomous intelligent agents to advanced traffic management systems. They examine the abilities of autonomous agents, neural networks and distributed artificial intelligent systems that are applicable to Intelligent Transportation 'Systems (ITS). The authors maintain that with the use of autonomous intelligent agents, advanced automation can be combined with more flexibility and better performance.
Semantic assessment of similarity between raster elevation datasets

This paper describes a method to assess the similarity between digital elevation models (DEM), based on the comparison of the landforms. The method attempts to mimic the one commonly used by human beings, which consists of comparisons among the shapes that a human subject identifies in the landscape. To do so, semantic similarity measurements are applied over a hierarchy of concepts. Our method is composed of two stages: the Geomorphometric Analysis and the Semantic Analysis. The first stage aims to represent the topographic properties using one of the concepts of the hierarchy, depending on an analysis of the DEM. The second stage consists of comparisons among the concepts that characterize the landscape using a measure of semantic similarity. In this stage, two levels of semantic analysis are defined: local and global. The advantage of our method is that the interpretation of the results is simplified by means of a semantic processing.
Trends of Homicidal Deaths in Indore (M.P.) Region One Year Retrospective Study

This study was done in Department of Forensic Medicine and Toxicology, Mahatma Gandhi Memorial Medical College, Indore (MP) from January to December 2012. Out of total 1931 post-mortem conducted in 2012, 82 cases were alleged homicidal in nature. Purpose of this study was to know the cause of death, pattern of weapon used for homicidal purpose, gender distribution, age distribution and seasonal distribution in homicidal death. Males were victim in 78.95%(64) of cases and females in 21.05%(18) of cases included in our study.
Effect of Aerobic Training on Percentage of Body Fat, Total Cholesterol and HDL-C among Obese Women

The aim of the present research was to determine the effect of aerobic training on Percentage of Body Fat, total Cholesterol (TC) and High Density Lipoprotein Cholesterol (HDL-C) among obese women. For this purpose, 20 female obese women (age17-25) were selected. The subjects received endurance training only one session in the morning between 6-7 am for three alternate days a week for six weeks. To analyse the collected data,'t'-ratio was used at 0.05 level of confidence. The results showed that there were significant changes in Percentage of Body Fat, TC and HDL-C. It was concluded that the aerobic training is widely believed to induce changes in the lipid profiles and Percentage of Body Fat of women.
QUALITY OF LIFE IN YOUNG PEOPLE WITH TYPE 1 DIABETES IN RELATION TO AGE AND GENDER

Background and Aim: Type 1 diabetes is one of the most common chronic metabolic disorders during childhood and adolescence period and has potentially life-threatening outcomes. Nowadays, the increasing number of children and adolescents with diabetes necessitates rigorous treatment programs. Also, for evaluating treatment effectiveness in diabetic patients, it is important to explore the quality of life and its related factors. The aim of this study was to examine quality of life in young people with type 1 diabetes in relation to age and gender. Materials and Method: It was a cross-sectional descriptive correlational study with a sample of 70 young people with type 1 diabetes referred to educational health care centers of Tehran University of Medical Sciences. The subjects were selected through non-probability sampling by consecutive method. Data collection instruments were demographics questionnaire and Diabetes Quality of Life (DQOL) questionnaire modified for young people and data were analyzed using independent t-test. Results: The results showed that 52.1% of the patients were female and 47.9% were male. The age range of the patients was 11-18 years (mean age 14.94 ± 2.75) and the duration of disease was 1-15 years (mean 2.23 ± 0.79). There was no statistically significant difference between different age and gender groups in terms of life satisfaction, impact of diabetes on life and worries about diabetes. Conclusion: The present study showed that age and gender were not determinant factors for quality of life in young people with type 1 diabetes.
Avoiding negligent release: contemporary clinical and risk management strategies.

Mental health professionals often must decide whether to release a psychiatric patient who has been committed for treatment on the basis of being mentally ill and dangerous. This decision involves liability risks if the patient becomes violent after release. The author draws together several recommendations made in the literature regarding the careful development and implementation of hospital release procedures, including 1) special consultation at the policy development stage, 2) preemptive judgments regarding the adequacy of hospital policies in relation to the professional standard of care, and 3) the use of videotaped exit interviews with patients at the time of their release. Language: en
PESQUISA DE FRAUDE NO LEITE UAT INTEGRAL COMERCIALIZADO NO ESTADO DO RIO DE JANEIRO E COMPARAÇÃO ENTRE OS MÉTODOS DE ANÁLISES FISICO-QUÍMICAS OFICIAIS E O METÓDO DE ULTRASSOM

The fraud in raw milk as product and in the milk ready for consumption represents an economic embezzlement and decreased industrial output that can be associated with health problems to consumers. The objectives of this study were to survey the quality of UHT milk sold in the metropolitan region of Rio de Janeiro, trough physical - chemical analysis and detection of the presence of fraud, evaluate the effectiveness of physical - chemical methods, comparing official methods reference to the method of ultrasound. For comparison of the analytical methods, the official methods and the ultrasound (70 Boecolac ® ) method by wore used. The presence of fraudulent substances wore not detected in 58 samples analyzed. The methods of ultrasound showed low correlation with the official methods for analysis of density, fat, freezing point and solids nonfat. The average values obtained were 3.22% fat, freezing point of - 0.5516oH, density of 1.029g/ml, pH of 6.69, and acidity of 0,1645% latic acid. The results presented in this study provide information for decisions taken by regulators, processors establishments and inspection of dairy products in directing the choice of methods of quality control to be practiced.
Study of multidrug resistance and extended spectrum beta lactamases producing Klebsiella pneumoniae isolated from hospitalized patients

Extended spectrum beta lactamases producing organism pose unique challenges to clinical microbiologist, infection control professional and antibacterial discovery scientists. Extended spectrum beta lactamases are enzymes that inactivate beta lactam antibiotic such as Penicillin, Ampicillin, fist generation cephalosporin antibiotic Cephalothin, second generation ISSN: 2319-7706 Volume 3 Number 1 (2014) pp. 30-37 http://www.ijcmas. com