Miracle-dz/UniFAR-FTUs huggingface dataset:
Zytogenetische Analyse der Spermienchromosomen bei Paaren mit habituellen Aborten

: Genetic factors, especially numerical chromosome anomalies, play an important role in embryonic loss. Since somatic cell analysis cannot assess the risk of errors arising de novo during germ cell maturation, we investigated, whether the male gametes from couples with habitual abortion (group HA) carry a higher rate of anomalies, than those from donors without reproductive dysfunction (group K). Chromosomes were demonstrated after fusion of sperm with zona-free golden hamster ova. Our results indicate no significant difference between the two groups for the total rates of aneuploidy (HA: 3.6%, K: 2.0%) and structural anomalies (HA: 15.3%, K: 7.0%). However, the levels of chromosome breaks and acentric fragments were significantly higher in the abortion group (5.8% and 8.1%, respectively, vs. 2.4% each in group K). The implications of this fact remain to be investigated.
Shai-Hulud: The quest for worm sign

Successful worm detection at real-time OC-48 and OC-192 speed requires hardware to extract web based binary sequences at faster than these speeds, and software to process the incoming sequences to identify worms. Computer hardware advancement in the form of field programmable gate arrays (FPGAs) makes real-time extraction of these sequences possible. Lacking are mathematical algorithms for worm detection in the real time data sequence, and the ability to convert these algorithms into lookup tables (LUTs) that can be compiled into FPGAs. Data Modeling provides the theory and algorithms for an effective mathematical framework for real-time worm detection and conversion of algorithms into LUTs. Detection methods currently available such as pattern recognition algorithms are limited both by the amount of time to compare the current data sequence with a historical database of potential candidates, and by the inability to accurately classify information that was unseen in the training process. Data Modeling eliminates these limitations by training only on examples of nominal behavior. This results in a highly tuned and fast running equation model that is compiled in a FPGA as a LUT and used at real-time OC-48 and OC-192 speeds to detect worms and other anomalies. This paper provides an overview of our approach for generating these Data Change Models for detecting worms, and their subsequent conversion into LUTs. A proof of concept is given using binary data from a WEBDAV, SLAMMER packet, and RED PROBE attack, with BASIC source code for the detector and LUT provided.
Visualizing intelligence information using correlation graphs

This paper presents a new information model to help intelligence analysts in organizing, querying, and visualizing the information present in large volumes of unstructured data sources such as text reports, multi-media, and human discourse. Our primary goal is to create a system that would combine the human pattern recognition abilities of intelligence analysis with the storage and processing capabilities of computers. Our system models the collective mental map of intelligence analysts in the form of the Correlation Graph, a modified graph data structure with objects and events as nodes and subjective probabilistic correlations between them as edges. Objects are entities such as people, places, and things. Events are actions that involve the objects. A taxonomy is also associated with the model to enable intelligence domain specific querying of the data. Graph drawing techniques are used to visualize the information represented by the correlation graph. Through real world examples, we demonstrate that the resulting information model can be used for efficient representation, presentation, and querying to discover novel patterns in the intelligence data via graph visualization techniques.
Numerical Simulation of Bone Regeneration in a Bone Chamber

While mathematical models are able to capture essential aspects of biological processes like fracture healing and distraction osteogenesis, their predictive capacity in peri-implant osteogenesis remains uninvestigated. We tested the hypothesis that a mechano-regulatory model has the potential to predict bone regeneration around implants. In an in vivo bone chamber set-up allowing for controlled implant loading (up to 90 μ m axial displacement), bone tissue formation was simulated and compared qualitatively and quantitatively with histology. Furthermore, the model was applied to simulate excessive loading conditions. Corresponding to literature data, implant displacement magnitudes larger than 90 μ m predicted the formation of fibrous tissue encapsulation of the implant. In contradiction to findings in orthopedic implant osseointegration, implant displacement frequencies higher than 1 Hz did not favor the formation of peri-implant bone in the chamber. Additional bone chamber experiments are needed to test these numerical predictions.
Fast encryption for multimedia

The security of multimedia data is important for multimedia commerce. The encryption algorithms with high security, such as DES and IDEA, may not be suitable to multimedia applications because large data sizes and real time constraint. This paper proposes a fast encryption algorithm for multimedia data, called FEA-M. FEA-M is based on Boolean matrix theory. The plaintext and the ciphertext are 64/spl times/64 Boolean matrices while the secret key is also a 64/spl times/64 matrix. The structure of FEA-M is chosen to provide confusion and diffusion and to facilitate both hardware and software implementation.
Impact of Guideline Implementation on Patient Care: a Cluster RCT

In Western European countries, dentists use standardized procedures, rather than individualized risk assessment, for routine oral examinations. The predictive hypothesis was that guideline implementation strategies based on multifaceted interventions would be more effective in patient care than the dissemination of guidelines only. A cluster-randomized trial was conducted, with groups of general dental practitioners (GDPs) as the unit of randomization. Patients were clustered within practices and prospectively enrolled in the trial. Patient data were collected from registration forms. The primary outcome measure was guideline-adherent recall assignment, and a secondary outcome measure was guideline-adherent bitewing frequency. The interventions consisted of online training, guideline dissemination, and educational sessions. For low-risk patients, guideline-adherent recall increased in the intervention group (+8%), which differed from the control group (−6.1%) (p = 0.01). Guideline-adherent bitewings showed mixed results. We conclude that multifaceted intervention had a moderate but relevant effect on the performance of GDPs, which is consistent with other findings in primary care.
Patients' perceptions and expectations of outpatient pharmacy services in a teaching hospital

A six‐week prospective study was carried out in a Singapore outpatient hospital pharmacy to assess patients' perceptions and expectations of pharmacy services. From a total of 1,273 self‐administered questionnaires distributed, 413 evaluable responses were returned. These showed that the most important services in the patient's view were a prescription filling waiting time of less than 30 minutes, medicines being dispensed accurately and reasonable pricing. The mean acceptable waiting times for prescription filling were 9.5 minutes for up to two items, 16.8 minutes for three to five items and 23.9 minutes for six or more items. Pharmacists' competency was rated significantly higher by respondents with higher education and higher incomes than by those with lower education and incomes, while the time spent with the pharmacist was rated less sufficient by respondents with a lower income than by those with higher incomes.
Motorische Verbesserungen durch Vojta-Physiotherapie bei Patienten mit multipler Sklerose und der Einfluß von Behandlungspositionen*

The project is intended to quantify immediate and long-term improvements over four weeks in multiple-sclerosis (MS) patients by means of Vojta physiotherapy as well as to determine the influence of treatment positions. 46 MS-patients with medium-degree disabilities were divided into two neurologically similar groups of 23 persons each: Group I was treated with only two, group II with numerous different positions. Improvements occurring immediately after the therapy in both groups were recorded by eight physiological tests while long-term improvements were recorded by ten physiological tests and by graduated examinations of muscular strength. An average immediate improvement in every person within the two groups could be proved in 83% of all cases; concerning the long-term improvement, positive results were recorded in about 80% of the cases. As a result of the individual physiological tests, the long-term improvements vary between 4 and 18% compared to the starting point and between 1 and 12% in the muscular strength examinations. Slightly larger improvement effects are achieved in the great majority of the tests in group II. There are several indications, particularly stronger and more consistent electromyographic activities during therapy, which make it probable that the greater improvements in this group are associated with the conception of treatment. Ziel der Untersuchung ist eine Quantifizierung von motorischen Sofort- und von 4-Wochen-Langzeit-Verbesserungen (LZV) durch die Vojta-Physiotherapie bei Multiple-Sklerose(MS)-Patienten sowie eine Klarung des Einflusses von Behandlungspositionen. 46 MS-Patienten mittleren Behinderungsgrades wurden in zwei ahnliche Gruppen von 23 Patienten unterteilt: Behandlungsgruppe I wurde aus zwei, Behandlungsgruppe II aus zahlreichen verschiedenen Positionen behandelt. Die Erfassung von sofort nach der Therapie auftretenden Verbesserungen erfolgte mit Hilfe von 8 physiologischen Tests, die LZV wurden uber 10 physiologische Tests sowie uber skalierte Muskelkraftprufungen erfast. Ermittelt man fur jede Person aus allen physiologischen Tests eine mittlere prozentuale Sofortverbesserung, so findet man bei 38 Personen positive Ergebnisse; fur die LZV bei 37. Bei den einzelnen physiologischen Tests liegen im Vergleich zur Ausgangssituation die LZV durchschnittlich zwischen 4 und 18% und bei den Muskelkraftprufungen zwischen 1 und 12%. Behandlungsgruppe II zeigt bei den weitaus meisten Tests etwas grosere Verbesserungseffekte. Es gibt mehrere Hinweise, u.a. starkere und einheitlichere elektro-myographische Aktivitaten wahrend der Therapie, die vermuten lassen, dass die groseren Verbesserungen bei der Behandlungsgruppe II mit der Behandlungskonzeption zusammenhangen.
Threshold for Detection of Incisal Forces Is Increased by Jaw Movement

Current knowledge regarding the sensitivity of the teeth to forces is based on psychophysical experiments that measured touch detection thresholds under static jaw conditions. It is not known whether jaw movements alter the perception of forces applied to the teeth, but, based on limb movement studies, it is hypothesized that the perception of mechanoreceptor outputs will be downwardly modulated by jaw movements. We predicted that, compared with static jaw conditions, rhythmic jaw movements would be associated with significantly higher psychophysical thresholds for the detection of incisally applied forces. In eight participants, mechanical pulses were delivered to an incisor during static jaw holding or during cyclic jaw opening and closing. Analogous to findings in human limbs, the psychophysical salience of periodontal mechanoreceptor feedback was downwardly modulated by physiologically relevant movements; detection thresholds for mechanical pulses applied to a central incisor were significantly higher during jaw-closing movements than during static jaw positioning.
Anti-NGF Treatment Reduces Bone Resorption in Periodontitis

Periodontitis is characterized by periodontal tissue destruction, including the alveolar bone. One of its critical components is the release of pro-inflammatory neuropeptides from sensory nerve endings innervating the periodontium. Since nerve growth factor (NGF) has been reported to up-regulate neuropeptides in sensory neurons, we hypothesized that it would be increased in ligature-induced periodontitis in rats, and that systemic NGF neutralization would reduce the periodontitis-associated alveolar bone resorption. Real-time PCR analysis disclosed a statistically significant time-dependent up-regulation of NGF mRNA in gingiva during 2 weeks of periodontitis. Interestingly, NGF up-regulation was also detected in the contralateral gingiva. In addition, immunohistochemistry of trigeminal ganglion neurons innervating the gingivomucosa demonstrated increased expression of TrkA receptor for NGF. Systemic anti-NGF treatment during periodontitis significantly reduced interleukin-1β expression in gingiva and bilateral alveolar bone resorption. This suggests that NGF promotes periodontal inflammation and implicates a possible use of anti-NGF treatment in periodontitis.
Young women smokers’ perceptions and use of counterfeit cigarettes: Would plain packaging make a difference?

Opponents of plain tobacco packaging argue that it would make production of counterfeit tobacco products cheaper; lower costs for consumers; confuse consumers in respect to product authenticity; and increase appeal and purchase of counterfeit tobacco. We explored the last of these contentions with young women smokers (N = 49), aged 16–24 years, recruited in Glasgow (Scotland). Participants were firstly asked about their perceptions and purchase of counterfeit cigarettes. Each group was then shown a mock display of legitimate and counterfeit plain cigarette packs. All the packs shown were the same colour (brown) with the only difference being the price and brand name. Participants were asked what brand they would smoke if all cigarettes came in brown (plain) packaging. Purchase of counterfeit cigarettes was lower for 16–17 year olds than 18–24 year olds. Perceptions of counterfeit cigarettes were negative, with concerns expressed about content and taste. All participants said that if pack appearance was standardised they would continue to smoke the same brand of legitimate cigarettes that they currently smoke or down-trade to cheaper legitimate brands. Non-users of counterfeit cigarettes indicated that they would remain non-users should all cigarettes come in uniform packaging. Counterfeit users, at least those willing to smoke counterfeit cigarettes again, indicated that they would still buy counterfeit cigarettes if pack appearance was standardised, primarily due to the lower price. For young women smokers in this study, plain packaging had no bearing on perceived appeal of counterfeit cigarettes.
Software CAD: A Revolutionary Approach

A research project is described in which an experimental software CAD environment called the Carleton embedded system design environment (CAEDE), oriented toward embedded systems and Ada, was developed to provide a demonstration of the concept and to serve as a research testbed. The major contribution of CAEDE is a demonstration of a visual paradigm which combines semantic depth and syntactic shallowness, relative to Ada, in a manner that makes it possible for the embedded-system designer to work in terms of abstract machines while still thinking Ada. A secondary contribution is the identification of Prolog as a promising approach for supporting tool development in an environment which supports the visual paradigm. Also described are experimental tools for temporal analysis, performance analysis, and the generation of skeleton Ada code. >
Life-course Determinants of Need for Dental Prostheses at Age 24

This study aimed to assess the prevalence of use and need for dental prostheses (UNDP) by individuals at age 24 and their life-course determinants. A representative sample (n = 720) of all 5914 births occurring in Pelotas in 1982 were prospectively investigated, and the UNDP were assessed in 2006. Exploratory variables included demographic and socio-economic, oral health, and dental service utilization patterns during the life-course. The prevalence of UNDP was 2.1% and 29.7%, respectively. Multivariable Poisson regression analysis showed that low socio-economic status through the life-course [Prevalence Ratio (PR) = 1.56 (95% CI: 1.08-2.26)], lower maternal schooling in childhood [PR 2.79 (1.34-5.79)], no oral hygiene instruction by a dentist at age 15 [PR 1.64 (1.11-2.41)], and caries presence at age 15 (high DMFT tertile) [PR 2.90 (1.98-4.24)] were associated with prosthetic treatment needs. These results support the hypothesis that life-course socio-economic, behavioral, and clinical determinants are associated with the need for dental prostheses.
PEDOT:PSS Films with Metallic Conductivity through a Treatment with Common Organic Solutions of Organic Salts and Their Application as a Transparent Electrode of Polymer Solar Cells.

UNLABELLED A transparent electrode is an indispensable component of optoelectronic devices, and there as been a search for substitutes of indium tin oxide (ITO) as the transparent electrode. Poly(3,4-ethylene dioxythiophene):poly(styrenesulfonate) ( PEDOT PSS) is a conducting polymer that is very promising as the next generation of materials for the transparent electrode if it can obtain conductivity as high as that of ITO. Here, we report the treatment of PEDOT PSS with organic solutions to significantly enhance its conductivity. Common organic solvents like dimethylformamide and γ-butyrolactone and common organic salts like methylammonium iodide and methylammonium bromide are used for the organic solutions. The conductivity of pristine PEDOT PSS films is only ∼0.2 S/cm, and it can be increased to higher than 2100 S/cm. The conductivity enhancement is much more significant than control treatments of PEDOT PSS films with neat organic solvents or aqueous solutions of the organic salts. The mechanism for the conductivity enhancement is the synergetic effects of both the organic salts and organic solvents on the microstructure and composition of PEDOT PSS. They induce the segregation of some PSSH chains from PEDOT PSS. Highly conductive PEDOT PSS films were studied as the transparent electrode of polymer solar cells. The photovoltaic efficiency is comparable to that with an ITO transparent electrode.
High Antibody Levels to P. gingivalis in Cardiovascular Disease

Recent evidence suggests that strain variation in the serum IgG response to Porphyromonas gingivalis occurs in periodontal disease and cardiovascular disease (CVD). This study aimed to test the hypothesis that different P. gingivalis strains would elicit different levels of IgG, depending on a patient’s cardiovascular (CV) and periodontal health. For CVD patients, serum antibody levels increased significantly with increasing numbers of deep pockets for all strains of P. gingivalis, except W50 (p < 0.001). We used a two-way analysis of variance to examine differences in antibody responses across several CV and periodontal groups simultaneously. There was a significant interaction effect (p < 0.05) between periodontal status and CV status for antibody levels to ATCC33277, UQD605, and Su63. This study shows variation in strain type with respect to serum IgG response in several CV and periodontal categories, providing further support for the role of the immune response to P. gingivalis in the relationship between periodontal disease and CVD.
12-year Survival of Composite vs. Amalgam Restorations

Information about the long-term clinical survival of large amalgam and composite restorations is still lacking. This retrospective study compares the longevity of three- and four-/five-surface amalgam and composite restorations relative to patients’ caries risk. Patient records from a general practice were used for data collection. We evaluated 1949 large class II restorations (1202 amalgam/747 composite). Dates of placement, replacement, and failure were recorded, and caries risk of patients was assessed. Survival was calculated from Kaplan-Meier statistics. After 12 years, 293 amalgam and 114 composite restorations had failed. Large composite restorations showed a higher survival in the combined population and in the low-risk group. For three-surface restorations in high-risk patients, amalgam showed better survival.
Non-target effects of commonly used plant protection products in roses on the predatory mite Euseius gallicus Kreiter & Tixier (Acari: Phytoseidae).

BACKGROUND Euseius gallicus Kreiter & Tixier (Acari: Phytoseidae) is a predatory mite recently available for use against various pests in roses. We tested in greenhouse trials the impact on the numbers of eggs and motiles of E. gallicus of the most commonly used plant protection products in roses in northern Europe: the acaricides acequinocyl and etoxazole, the insecticides azadirachtin-A, acetamiprid, flonicamid, imidacloprid, indoxacarb, thiacloprid and thiamethoxam and the fungicides boscalid and kresoxim-methyl, cyprodinil + fludioxonil, dodemorph and fluopyram + tebuconazole. RESULTS The neonicotinoids thiacloprid, thiamethoxam, acetamiprid and imidacloprid had a negative impact on the number of eggs (47, 62, 81 and 76% reduction, respectively, compared with a water treatment) and number of motiles of E. gallicus (42.2, 42.9, 59.9 and 60.6% reduction) and were classified as slightly to moderately toxic. Also, the number of motiles was reduced after treatment with acequinocyl (47%) and etoxazole (43.9%) and after two treatments with flonicamid (41%) with a 1 week interval between treatments. CONCLUSION Azadirachtin-A, acetamiprid, flonicamid, boscalid and kresoxim-methyl, cyprodinil + fludioxonil, dodemorph and fluopyram + tebuconazole were harmless for E. gallicus. Special attention should be paid to the impact of neonicotinoids and of acequinocyl and etoxazole, and to the application frequency with flonicamid on E. gallicus. © 2015 Society of Chemical Industry.
Proteases of an Early Colonizer Can Hinder Streptococcus mutans Colonization in vitro

Streptococcus mutans is the primary cariogen that produces several virulence factors that are modulated by a competence-stimulating peptide (CSP) signaling system. In this study, we sought to determine if proteases produced by early dental plaque colonizers such as Streptococcus gordonii interfere with the subsequent colonization of S. mutans BM71 on the existing streptococcal biofilms. We demonstrated that S. mutans BM71 colonized much less efficiently in vitro on streptococcal biofilms than on Actinomyces naeslundii biofilms. Several oral streptococci, relative to A. naeslundii, produced proteases that inactivated the S. mutans CSP. We further demonstrated that cell protein extracts from S. gordonii, but not from A. naeslundii, interfered with S. mutans BM71 colonization. In addition, S. mutans BM71 colonized more efficiently on the sgc protease knockout mutant of S. gordonii than on the parent biofilms. In conclusion, proteases of early colonizers can interfere with subsequent colonization by S. mutans in vitro.
A comprehensive bibliography of linguistic steganography

In this paper, we will attempt to give a comprehensive bibliographic account of the work in linguistic steganography published up to date. As the field is still in its infancy there is no widely accepted publication venue. Relevant work on the subject is scattered throughout the literature on information security, information hiding, imaging and watermarking, cryptology, and natural language processing. Bibliographic references within the field are very sparse. This makes literature research on linguistic steganography a tedious task and a comprehensive bibliography a valuable aid to the researcher.