Miracle-dz/UniFAR-FTUs huggingface dataset:
Diagnostic microbiologique des mucormycoses

Les mucormycoses sont des infections invasives provoquees par des champignons filamenteux ubiquitaires appartenant l’ordre des Mucorales . Elles surviennent notamment chez des patients immunodeprimes, diabetiques ou ayant subi une transplantation d’organe. A l’heure actuelle, il n’existe pas de recommandations francaises pour le diagnostic de laboratoire des mucormycoses. Ce diagnostic repose principalement sur l’examen histologique et la mise en culture de l’echantillon clinique. Il n’existe pas de techniques standardisees qui soient une alternative au diagnostic microbiologique. Nous recapitulons ici les methodes microbiologiques utilisees dans la demarche diagnostique de la maladie ainsi que dans l’identification des Mucorales .
Bioassay Using a Labeled Oligonucleotide Obtained by in Vitro Selection

A new bioassay system using an oligodeoxyribonucleotide (DNA) obtained by the in vitroselection method is described. The DNA aptamer which selectively binds to a target molecule, Reactive Green 19 (RG19), was labeled with fluorescein. The circular dichroism spectra revealed that the fluorescein labeling did not significantly affect the conformation of the DNA. The binding affinity toward RG19 of the labeled DNA was the same as that of the nonlabeled DNA. Using the labeled DNA and the RG19‐immobilized gel, a semiquantitative assay of RG19 concentration was performed.
Inhibition of CYP 17, a New Strategy for the Treatment of Prostate Cancer

Androgens are growth factors for approximately 80 percent of all prostate cancers. Suppressing androgen biosynthesis is therefore an important therapeutic strategy in order to inhibit tumor growth. Unfortunately, the drugs currently applied to lower androgen levels only affect testicular androgen production. Since androgens are also synthesized in the adrenal glands, tumor stimulation cannot be blocked completely. A new therapeutic target, CYP 17 (P450 17, 17α‐hydroxylase‐C17, C20 lyase), is likely to improve this situation. CYP 17 is a P450 enzyme and catalyzes the last step of androgen biosynthesis in both testes and adrenals. Inhibition of this enzyme will therefore result in a complete block of androgen production. This paper gives an overview of the current situation in this novel field of drug research and focuses on the development of steroidal and non‐steroidal inhibitors of CYP 17.
Fast checkpoint and recovery techniques for an in-memory database

Multicore in-memory databases for modern machines can support extraordinarily high transaction rates for online transaction processing workloads. A potential weakness of such databases, however, is recovery from crash failures. We show that techniques for disk-based persistence can be efficient enough to keep up with current systems’ huge memory sizes and fast transaction rates, be smart enough to avoid additional contention, and provide fast recovery. This thesis presents SiloR, a persistence system built for a very fast multicore database system called Silo. We show that naive logging and checkpoints make normal-case execution slower, but that careful design of the persistence system allows us to keep up with many workloads without negative impact on runtime performance. We design the checkpoint and logging system to utilize multicore’s resources to its fullest extent, both during runtime and during recovery. Parallelism allows the system to recover fast. Experiments show that a large database (≈ 50 GB) can be recovered in under five minutes. Thesis Supervisor: Barbara Liskov Title: Professor
Distinct spatial and temporal distributions of aggrecan and versican in the embryonic chick heart

Although chondroitin sulfate proteoglycans (CSPGs) are major components of the embryonic extracellular matrix, little attention has been paid to specific CSPGs in early heart development, in part because appropriate antibodies were not available. Therefore we prepared specific polyclonal antibodies against chicken aggrecan, versican, neurocan, and phosphacan. Western blotting and immunohistochemical studies revealed the presence of aggrecan and versican in stages 12–21 chicken embryo hearts in distinctive spatial and temporal patterns. Because this is the first demonstration of aggrecan in heart tissue, we further used RT‐PCR to confirm that aggrecan is expressed in the heart and in situ hybridization to confirm the pattern of expression determined using antibodies. Versican is found in the myocardium and the myocardial basement membrane. In contrast, aggrecan is specifically colocalized with several groups of migrating cells including endocardial cushion tissue cells, epicardial cells, a mesenchymal cell population in the outflow tract that may be of neural crest origin, and a mesenchymal cell population in the inflow tract. The combined observations indicate that versican and aggrecan are expressed in unique patterns and suggest that they play very different roles in development. Anat Rec 256:366–380, 1999. © 1999 Wiley‐Liss, Inc.
Phylogenetic Species, Nested Hierarchies, and Character Fixation

Cladistic mechanics and ramifications of various species concepts rooted in phylogenetic theory are explored. Published discussions of the phylogenetic species concept (PSC) have been hampered by persistent misconceptions surrounding its ontology and applicability, and by confusion of various incompatible versions of species concepts claiming to follow from Hennig's (1966), Phylogenetic Systematics, Univ. of Illinois Press, Urbana work. Especially problematic are topology‐ or tree‐based versions of species diagnosis, which render diagnoses dependent on relationships depicted as hierarchically structured regardless of any lack of underlying hierarchy. Because the applicability of concepts such as monophyly, paraphyly, and polyphyly rests ultimately on the underlying hierarchical distribution of characters, representations of tokogenetic or reticulating systems as nested hierarchies are necessarily inaccurate. And since hierarchical representations—even if accurate—of nonrecombining genetic elements need not coincide with the organisms that bear them, tree‐based diagnoses are further hampered, except potentially as retrospective tools. The relationship between tree‐based species delineations and the criterion of character fixation is explored. Fixation of characters by which one identifies phylogenetic species is further distinguished from the fixation of character state differences, and the implications of that distinction are explored with reference to the interpretation of speciation events. It is demonstrated that character fixation in alternative species need not coincide with the achievement of reciprocal monophyly. While the PSC retains shortcomings, some of the more frequently criticized aspects of the PSC are functions of sampling that are no more problematic than for any basic systematic endeavor.
Effects of atmospheric CO2 enrichment and foliar methanol application on net photosynthesis of sour orange tree (Citrus aurantium; Rutaceae) leaves

Foliar spray applications of 40% aqueous methanol were made to sunlit leaves of sour orange trees that had been grown continuously in clear-plastic-wall open-top enclosures maintained out-of-doors at Phoenix, Arizona, for over 5.5 years in ambient air of approximately 400 {mu}mol mol{sup -1} CO{sub 2} and in air enriched with CO{sub 2} to a concentration of approximately 700 {mu}mol mol{sup -1}. No unambiguous effects of the methanol applications were detected in photosynthesis measurements made on foliage in either of the two CO{sub 2} treatments. THe 75% increase in CO{sub 2}, however, raised the upper-limiting leaf temperature for positive net photosynthesis by approximately 7 C, which resulted in a 75% enhancement in net photosynthesis at a leaf temperature of 31 C, a 100% enhancement at a leaf temperature of 35 C, and a 200% enhancement at 42 C. 13 refs., 2 figs., 1 tab.
V-BLAST/MAP: A NEW SYMBOL DETECTION ALGORITHM FOR MIMO

V-BLAST/MAP: A NEW SYMBOL DETECTION ALGORITHM FOR MIMO CHANNELS Yavuz Yapıcı M.S. in Electrical and Electronics Engineering Supervisor: Prof. Dr. Erdal Arıkan 2005, January In this thesis, we introduce a new symbol detection algorithm for MIMO channels. This algorithm is an extension of the well-known V-BLAST algorithm. The new algorithm, V-BLAST/MAP, combines elements of the V-BLAST algorithm and the maximum a-posteriori (MAP) rule. The original V-BLAST algorithm is a multi-layer symbol detection scheme which detects symbols transmitted at different transmit antennas successively in a certain data-independent order. The proposed V-BLAST/MAP algorithm differs from V-BLAST only in the ordering strategy of the symbols detected. The complexity of the V-BLAST/MAP is higher than that of V-BLAST; however, the performance improvement is also significant. Simulations show that V-BLAST/MAP achieves symbol error rates close to the optimal maximum likelihood (ML) scheme while retaining the low-complexity nature of the V-BLAST.
Níveis de lisina digestível para poedeiras Hy-Line W-36 em produção

In this experiment it was aimed to determine the best levels of digestible lysine for laying hens in production period. Performance, nutrients intake, metabolism, egg quality, blood parameters and development of reproductive tract for 160 Hy-Line W-36 hens at 25 weeks of age. Hens were distributed in a completely randomized design with four levels of digestible lysine (600, 700, 800 or 900 mg of Lys/kg) and four replicates by using a split spot scheme was used at evaluation of nitrogen balance, blood parameters and reproductive tract. Lysine levels in the diet affected food, protein and energy intakes whose maximum point was noted at the level of 720 mg of Lysine. For egg production, food conversion, and nitrogen balance, the best levels of lysine was 800 mg, 900 mg, and 700 mg, respectively. The digestibility of ethereal extract, egg quality, development of reproductive tract and blood parameters were not affected by levels of digestible lysine in the diet. It is suggested 700 and 800 mg of digestible lysine for metabolism and performance, respectively, and 600 mg for egg quality and better development of the reproductive trait.
NoteMate - A Note Making System Using OCR and Text Mining

in today’s world, all aspects of our lives have a digital presence. There are high performance cell-phones, laptops and tablets all around us. With the prominent and daily use and integration of technology to a student’s daily routine, utilization of their mobile gadgets for educative purposes can be advantageous both to students and teachers alike. Note Mate is an application which uses this fact to attempt to digitize the activity of Note-Making. It is based on Android platform with cloud as the storage medium. In this project, we are implementing Optical character recognition in order to convert handwritten scripts on a touch screen device into text format, which can be stored for later retrieval or editing using any text-editor software. A simplified neural approach to recognition of optical or visual characters is portrayed. Tools and services for users to download educational contents interact with teachers as well as other pupils to discuss topics and also extract the accurate information as per requirement are also provided. Keywords— OCR , NoteMate, Text Mining, Template Matching, Android.
Sine-Wave Tracking Revisited

A study of sine-wave tracking is reported which illustrates the extent to which the predictability of the input and of the control device dynamics can be utilized with extended practice. Analysis of the error power spectra establishes the presence of a stable source of noise power in the operator's output that has implications for deriving models of manual tracking performance.
Immunohistochemical analysis of integrin αvβ3 expression on tumor‐associated vessels of human carcinomas

Expression of the αvβ3 integrin is upregulated on sprouting endothelia. Systemic application of antibody or peptidic inhibitors of αvβ3 function disrupts tumor angiogenesis and reduces growth and invasiveness of human tumors in animal models. We systematically investigated αvβ3 expression on tumor‐associated vessels of 4 different human epithelial tumors and the corresponding normal tissues by means of immunohistochemistry on frozen sections using the αvβ3‐complex specific monoclonal antibody LM609. Variable levels of LM609 staining were found in all carcinoma lesions. A considerable number of tumor tissues (35/50) expressed αvβ3 on more than 50% of their vessels. Inflammatory infiltrates and the possibly hypoxic conditions near necrotic areas of tumors were accompanied by an increased αvβ3 expression. Remarkably, the vasculature in apparently normal tissue also stained for αvβ3. However, the percentages of stained vessels and their staining intensity were lower than in neoplastic tissues. Besides the vascular αvβ3 expression, several extravascular cell types stained positive, in both normal and tumor specimens. Taken together, our findings show a considerable number of colon, pancreas, lung and breast carcinoma lesions with many αvβ3‐expressing vessels that could be targets for anti‐αvβ3‐therapy. Int. J. Cancer 71:320‐324, 1997. © 1997 Wiley‐Liss Inc.
Synesthésie, expression subjective d’un palimpseste neuronal ?

Synesthetes, a small fraction of the population, experience systematic, additional associations. For example, they may arbitrarily associate a specific color to each letter or number. Synesthesia has offered for the last ten years to cognitive science a unique opportunity to study the neural bases of subjective experience, drawing on individual differences just like in neuropsychology, but with healthy people. Here we review the current knowledge and propose a new theory, the "palimpsest hypothesis", a variant of the recycling hypothesis for reading. The neural development of written language expertise (a recent cultural invention acquired without any genetic modification) requires indeed the recycling of brain regions predisposed to expertise acquisition into reading regions. The palimpsest hypothesis supposes that for synesthetes recycling involves neuronal networks that were already specialized for color perception. Synesthetic colors would be the remains of this former expertise.
A control of biped robot which applies inverted pendulum mode with virtual supporting point

We applied the inverted pendulum mode to the control of a biped robot in order to plan a trajectory in real time. Though the inverted pendulum mode is useful to plan a trajectory, the stability margin of a biped robot is very narrow because of its structural limit. Virtual supporting point (VSP), a new indicator of biped robot control, is suggested with a view to broaden the stability margin of biped robot. Walking parameters could be adjusted by setting VSP without changing other parameters. The mobility of a biped robot is improved compared to the usual method if proper VSP is set. The stable range of VSP is figured out by revealing the relationship between ZMP and VSP. Additionally, biped locomotion could be designed simply and its stability could be determined clearly beforehand by applying VSP. Results of the simulation and the experiment shows the validity of the suggested method.
Élongation de l’embryon : un mouvement cellulaire aléatoire

> Au cours de son developpement, l’embryon de vertebres subit une serie de changements morphogenetiques necessaires a la differenciation correcte de toutes les structures de l’individu adulte. Durant les premieres etapes de la vie, l’embryon est constitue d’un groupe de cellules organisees en une structure symetrique ronde. Puis, lors de la gastrulation, etape de mise en place des trois feuillets embryonnaires (endoderme, mesoderme et ectoderme), cette symetrie est brisee et l’embryon s’allonge selon l’axe anteroposterieur (ou tete/queue) (Figure 1A). La formation du corps se produit de maniere progressive en commencant d’abord par la tete, puis le cou, le thorax et enfin l’abdomen. Les ebauches de ces differentes structures sont progressivement formees a partir de la partie posterieure de l’embryon appelee bourgeon caudal (Figure 1B).
Encadrement de l’excitabilité des motoneurones par la sérotonine

> Le mouvement, qu’il soit volontaire ou non, est declenche par le systeme nerveux central. Il se traduit par l’activation des motoneurones, voie finale commune du systeme nerveux (Figure 1). L’information electrique provenant d’autres neurones est integree au niveau du segment initial de l’axone (SIA), qui genere ou non un potentiel d’action qui se propage le long de l’axone. Chaque fois qu’un potentiel est genere, cela se traduit par une contraction musculaire et, le plus souvent, un mouvement. Il est donc essentiel pour le systeme nerveux central de controler precisement l’activite des motoneurones. Dans cette nouvelle, nous montrerons comment la serotonine encadre l’excitabilite des motoneurones, jouant ainsi un role essentiel pour le controle moteur.
Nonessentiality of Concurrent Cell Divisions for Degree of Polarization of Leaf Growth. I. Studies with Radiation-Induced Mitotic Inhibition

During germination and seedling growth, the first foliage leaf of wheat shows polarized growth with striking changes in shape. During this polarized growth, most of the new cell plates are formed perpendicular to the axis of greatest elongation (longitudinal axis). The relation between leaf length and leaf width is the same in leaves normally growing with cell division as in leaves growing with negligible cell division after gamma-irradiation (800 kr) of the unsown grain. Although cell division is necessary for continued growth and normal developmcnt, concurrent cell divisions play no role in determining the degree of polarization, i.e., the ratio of the rates of linear extension in length per mm length to linear extension in width per mm width. The majority of the new cell plates formed before the growth period studied was parallel to the axis of greatest absolute and relative elongation during the growth period studied. Irradiated and unirradiated wheat having the same leaf size, and thus the same leaf shape, have quite different cell sizes, shapes, and numbers in both the leaf epidermis and the chlorenchymatous mesophyll. It is concluded that the orientations of cell divisions, whether concurrent with or prior to the growth period studied, playmore » no role in the basic mechanism which determines the manner in which leaves change shape; and genetic information specifies leaves form independently of genetic influences on sizes and shapes of cells and on the extents and orientations of cell divisions. (auth)« less
Dynamics of clustering multiple backpropagation networks

It is known that synergistic effects of clustering multiple backpropagation nets improves supervised learning, generalization, fault tolerance, and self-organization with respect to a comparably complex nonclustered system. A model that captures the underlying reasons for the synergy of clustering is outlined. The underlying ideas can apply to any net trained with a supervised learning rule. <<ETX>>
Les souris ne sont pas des hommes et pourtant… : Ce que les souris humanisées nous apprennent sur les maladies infectieuses

L’etude des pathologies humaines est souvent limitee par l’absence de modele animal approprie. La souris est le modele le plus frequemment utilise pour l’etude des maladies infectieuses humaines. Cependant, un grand nombre d’agents infectieux specifiques de l’homme n’infectent pas la souris. Ces vingt dernieres annees, la greffe de cellules progenitrices ou de tissus humains chez des souris immunodeficientes a permis de generer des souris dites humanisees. Bien que ces modeles demandent encore a etre ameliores, ils ont permis de reproduire chez la souris certains aspects des pathologies humaines et laissent ainsi esperer le developpement dans un futur proche de therapies innovantes.
Digestão dos carboidratos de alimentos volumosos em eqüinos

Neste estudo, foram realizados dois ensaios com os objetivos de avaliar o fracionamento dos carboidratos de alimentos volumosos e estimar a digestibilidade desses nutrientes em dois ensaios de digestao com equinos. No ensaio 1, foram utilizados cinco equinos em delineamento de blocos casualizados, com sete tratamentos - fenos de alfafa (Medicago sativa); amendoim forrageiro (Arachis pintoi); desmodio (Desmodium ovalifolium); guandu (Cajanus cajan); macrotiloma (Macrotyloma axillare); estilosantes (Stylosanthes guianensis); ou coastcross (Cynodon dactylon) - avaliados pela tecnica de sacos de nailon moveis. No ensaio 2, foram utilizados quatro equinos em delineamento quadrado latino 4 × 4, alimentados com feno de coastcross em quatro tipos de moagem com o objetivo de avaliar se a reducao do tamanho de particula interfere na digestibilidade dos carboidratos. Os resultados comprovaram que os equinos possuem alta eficiencia na digestao dos carboidratos nao-fibrosos e de suas fracoes hidrolisaveis e rapidamente fermentaveis. Os fenos de amendoim forrageiro, estilosantess e macrotiloma apresentaram elevada digestibilidade dos carboidratos fibrosos e nao-fibrosos, enquanto a digestibilidade de todos os nutrientes do amendoim forrageiro foi superior a 70%, o que indica potencial para uso desta leguminosa em dietas para equinos. O processamento do feno de coastcross nao influenciou a digestibilidade das fracoes dos carboidratos fibrosos e nao-fibrosos. A analise dos carboidratos fibrosos e nao-fibrosos e um bom indicativo do valor nutricional dos alimentos e pode ser incluida na avaliacao da qualidade de alimentos para equinos.
Structured light face-scan implementation for OGRE

In dieser Arbeit wird mit Hilfe eines interactive Whiteboards ein einfacher Gesichts-Scanner implementiert. Basierend auf dem structured light Prinzip wird mit dem Beamer des interactive Whiteboards ein dunner Lichtstrahl auf das Gesicht einer Person projeziert, der sich langsam uber das Gesicht bewegt. Dies wird mit einer handelsublichen HD-Webcam aufgenommen, die vorher kalibriert wurde. Danach wird das gescannte Gesicht mit Hilfe des Open-Source 3D-Programms Ogre3d dargestellt. %%%%This thesis describes the implementation of a face-scanner with the help of an interactive whiteboard. Based on the principle of structured light, the projector of the whiteboard projects a thin light beam on the face of a person which moves slowly from over the face. An off-the-shelf HD webcam, which was calibrated before, was used to capture the scan. At the end the scanned face gets displayed as a 3D-model with the help of the open-source 3D engine OGRE.