Miracle-dz/UniFAR-FTUs huggingface dataset:
Deception and Confession : Experimental Evidence from a Deception Game in Japan

This study investigated lying behavior and the behavior of people who are deceived by using a deception game (Gneezy, 2005) in both anonymity and face-to-face treatments. Subjects consist of students and non-students (citizens) to investigate whether lying behavior is depended on socioeconomic backgrounds. To explore how liars feel about lying, we give senders a chance to confess their behaviors to their counter partner for the guilty aversion of lying. The following results are obtained: i) a frequency of lying behavior for students is significantly higher than that for non-students at a payoff in the anonymity treatment, but that is not significantly difference between the anonymity and face-to-face treatments; ii) lying behavior is not influenced by gender; iii) a frequency of confession is higher in the face-to-face treatment than in the anonymity treatment; and iv) the receivers who are deceived are more likely to believe a sender’s message to be true in the anonymity treatment. This study implies that the existence of the partner prompts liars to confess their behavior because they may feel remorse or guilt.
Sub-electron CIS noise analysis in 65 nm process

For a 4T pixel-based CMOS image sensors (CIS) readout chain, with column-level amplification and CDS, we show that the input-referred total noise in a standard 65 nm process can be reduced to 0.37 e−rms. Based on transient noise simulation using Eldo, the deep sub-electron noise performance have been reached using only circuit techniques and optimal device choices. The simulation results have been favorably compared with analytical noise calculations. The shot noise associated to the gate tunneling current has been simulated and the possibility of photoelectron counting in this 65 nm process has been demonstrated.
Practical uses of ultrasound in early pregnancy in cattle

Using a 'real-time' ultrasound scanner with a 3.5 MHz rectal transducer, a herd of 80 Friesian cows were scanned at weekly intervals during early pregnancy to assess the accuracy of pregnancy diagnosis, and the accuracy of twin detection. The growing fetuses were also measured to determine the relationship between crown-rump length and age. The accuracy of detection of pregnancy was inversely proportional to the age of the cow (r -0.967), the accuracy of detection of twinning was 100 per cent and there was strong correlation between fetal crown-rump length and age (r 0.98).
Inhibition of the Mitotic Exit Network in Response to Damaged Telomeres

When chromosomal DNA is damaged, progression through the cell cycle is halted to provide the cells with time to repair the genetic material before it is distributed between the mother and daughter cells. In Saccharomyces cerevisiae, this cell cycle arrest occurs at the G2/M transition. However, it is also necessary to restrain exit from mitosis by maintaining Bfa1-Bub2, the inhibitor of the Mitotic Exit Network (MEN), in an active state. While the role of Bfa1 and Bub2 in the inhibition of mitotic exit when the spindle is not properly aligned and the spindle position checkpoint is activated has been extensively studied, the mechanism by which these proteins prevent MEN function after DNA damage is still unclear. Here, we propose that the inhibition of the MEN is specifically required when telomeres are damaged but it is not necessary to face all types of chromosomal DNA damage, which is in agreement with previous data in mammals suggesting the existence of a putative telomere-specific DNA damage response that inhibits mitotic exit. Furthermore, we demonstrate that the mechanism of MEN inhibition when telomeres are damaged relies on the Rad53-dependent inhibition of Bfa1 phosphorylation by the Polo-like kinase Cdc5, establishing a new key role of this kinase in regulating cell cycle progression.
Cognitive functioning in late-life bipolar disorder.

OBJECTIVE This study characterized cognitive functioning in elderly patients with bipolar disorder. METHOD The cognitive functioning of 18 euthymic patients with a history of bipolar disorder I or II, ages 60 years and older, was tested with the Mini-Mental State Examination (MMSE), the Mattis Dementia Rating Scale, and the Executive Interview. Cognitive functioning in these subjects was compared with that of an age- and education-matched group of 45 comparison subjects without mood disorders. RESULTS Approximately half of the bipolar subjects scored one or more standard deviations below the mean of the comparison subjects on the MMSE (N=8, 44%) and the Mattis Dementia Rating Scale total (N=10, 56%). On the Executive Interview, three subjects (17%) scored between one and two standard deviations below the mean of the comparison subjects. CONCLUSIONS A significant proportion of older bipolar subjects exhibited neuropsychological deficits when they were clinically euthymic.
Breastfeeding, Other Early Life Exposures and Childhood Leukemia and Lymphoma

ABSTRACT Childhood cancer incidence increases and although rare, it is a leading cause of mortality. Leukemia and lymphoma comprise 40% of all cancers in children but little is known of their etiology. In this study, we examined the associations of breastfeeding and other early life exposures with childhood leukemia and lymphoma. A population-based case–control study carried out in 2011–2013 comprised mothers of 190 incidents (2005–2013) of leukemia/lymphoma cases aged 1–19 yr at diagnosis and 384 population-based controls. Interviews based on a computerized structured questionnaire were conducted with the mothers. Multivariate logistic regression models adjusted for potential confounders assessed the association between breastfeeding patterns and childhood leukemia/lymphoma. Ever breastfeeding category was associated with a 64% decreased risk for childhood leukemia/lymphoma lsqb;odds ratio (OR) = 0.36, 95% confidence interval (CI): 0.22, 0.60lrqb; and similar trends, with a dose–response effect, were observed for any breastfeeding (exclusive and/or partial) category for 6, 12, and 18+ mo. Other infant exposures associated with cancer risk were child iron supplementation (OR = 0.39, 95% CI: 0.26, 0.59), pet ownership (OR = 0.50, 95% CI: 0.33, 0.78), paternal smoking (OR = 1.93, 95% CI: 1.18, 3.15), and having older siblings (OR = 1.18, 95% CI: 1.05, 1.33). Breastfeeding—a controllable and modifiable exposure—is inversely associated with risk for childhood leukemia and lymphoma with a dose–response effect.
Towards a GPU-only rod-based hair animation system

Hair is one of the key aspects which make virtual characters believable, with physically based simulation the preferred animation approach. In [Kmoch et al. 2009], we presented a method based on Discrete Elastic Rods [Bergou et al. 2008]. Each guide strand is an elastic rod, given by its centreline, discretized into a chain of n + 2 nodes connected by n + 1 segments, and its material frame, two orthonormal vectors perpendicular to each segment (Fig. 1, left).
Relationship-Based Support for Women Living with Serious Mental Illness

Relationships are critical to a woman's growth and development, yet when living with serious mental illness, developing and nurturing connections can be challenging. This qualitative study explored the nature and quality of support provided within relationships for 14 women with schizophrenia. Families were key supporters. Female friends with mental illness often provided a meaningful source of connection for participants. Problematic relationships, losses over time, and living in poverty were among the barriers to receiving needed support. Participants conveyed a sense of wanting relational reciprocity as they talked about their relationships and place within the community.
Talking to Ourselves “among the Innocent Dead”: On Reconciliation, Forgiveness, and Mourning

~O ~ Ash, Timothy Garton. "True Confessions. " New York Re'O5~ view of Books 17 July 1997: 33-34, 36-37. 'O Friedman, Roger. "Widows to Testify at Hearings. " Cape Times 15 Apr. 1996. Independent Online. 16 Apr. 1996 . E "Killing of Amy Biehl. " Pt. 1. Amnesty Hearings and Deci'0nV ~ sions. Truth and Reconciliation Commission. 13 Nov. 2001 . ,^, ~ Krog, Antjie. Country of My Skull: Guilt, Sorrow, and the Limits of Forgiveness in the New South Africa. New ^Of: ~ York: Random, 1998. Ita ~ Long Night's Journey into Day. Dir. Frances Reid and DebIt*v ~ orah Hoffman. California Newsreel, 2000. Minow, Martha. Between Vengeance and Forgiveness: Facing History after Genocide and Mass Violence. Boston: Beacon, 1998.
Serum bilirubin: a simple routine surrogate marker of the progression of chronic kidney disease

Abstract Background: Studies suggest that Chronic Kidney Disease (CKD) is a global burden health associated with significant comorbid conditions. Few biochemical parameters have gained significance in predicting the disease progression. The present work aimed to study the association of the simple biochemical parameter of serum bilirubin level with the estimated glomerular filtration rate (eGFR), and to assess their association with the co-morbid conditions in CKD. Methods: We recruited 188 patients with CKD who attended a Nephrology out-patient department. eGFR values were calculated based on the serum creatinine levels using CKD-EPI formula. Various biochemical parameters including glucose, creatinine, uric acid, total and direct bilirubin were assayed in all study subjects. Study subjects were categorized into subgroups based on their eGFR values and their diabetic status and the parameters were compared among the different subgroups. Results: We observed a significantly decreased serum bilirubin levels (p < 0.001) in patients with lower eGFR values, compared to those with higher eGFR levels. There was a significant positive correlation between the eGFR levels and the total bilirubin levels (r = 0.92). We also observed a significant positive correlation between the eGFR levels and the direct bilirubin levels (r = 0.76). On multivariate linear regression analysis, we found that total and direct bilirubin independently predict eGFR, after adjusting for potential confounders (p < 0.001). Conclusions: Our results suggest that there is significant hypobilirubinemia in CKD, especially with increasing severity and co-existing diabetes mellitus. This finding has importance in the clinical setting, as assay of simple routine biochemical parameters such as serum bilirubin may help in predicting the early progression of CKD and more so in diabetic CKD.
Synaptic connections of distinct interneuronal subpopulations in the rat basolateral amygdalar nucleus

Although it is well established that the activity of pyramidal projection neurons in the basolateral amygdala (ABL) is controlled by γ‐aminobutyric acid (GABA)ergic inhibitory interneurons, very little is known about the connections of specific interneuronal subpopulations in this region. In the present study, immunohistochemical techniques were used at the light and electron microscopic levels to identify specific populations of interneurons and to analyze their connections with each other and with unlabeled presumptive pyramidal neurons. Double‐labeling immunofluorescence experiments revealed that antibodies to vasoactive intestinal peptide (VIP) and calbindin‐D28K (CB) labeled two separate interneuronal subpopulations in the ABL. Light microscopic double‐labeling immunoperoxidase experiments demonstrated that many VIP‐positive (VIP+) axon terminals formed intimate synaptic‐like contacts with the CB‐positive (CB+) neurons and that both CB+ and VIP+ terminals often contributed to the formation of pericellular baskets that surrounded unlabeled perikarya of pyramidal neurons. By using a dual immunoperoxidase/immunogold‐silver procedure at the ultrastructural level, it was found that 30% of VIP+ terminals in the anterior subdivision of the basolateral nucleus innervated interneurons that were either CB+ (25%) or VIP+ (5%). A smaller percentage (15%) of CB+ terminals formed synapses with labeled interneurons. Both VIP+ and CB+ terminals also innervated unlabeled perikarya, dendrites, and spines, most of which probably belonged to pyramidal neurons. The interconnections between interneurons may be important for disinhibitory mechanisms and the mediation of rhythmic oscillations in the ABL. J. Comp. Neurol. 456:217–236, 2003. © 2003 Wiley‐Liss, Inc.
Modélisation de l'aléa tsunamis et des résonances côtières en France

L'objectif de cette these est d'approfondir la connaissance de l'alea tsunami et des resonances cotieres en France. Dans une premiere partie, nous avons expose les differents elements de modelisation des resonances et des tsunamis dans l'approximation en ondes longues et de Boussinesq avec la technique des differences finies. Tous ces elements ont ete compares et valides lors de benchmarks. Un code resolvant les equations de la dynamique des fluides dans l'approximation de Boussinesq a ete developpe et valide. La seconde partie a consiste en un ensemble d'applications. Dans un premier temps, nous avons etudie differents evenements qui se sont produits dans l'ocean Pacifique. Une etude detaillee du tsunami genere par le seisme de Maule (Mw8. 8 28 fevrier 2010) est faite en champ proche (au niveau de la cote chilienne) comme en champ lointain (sur des bouees au large comme en Polynesie francaise). Une comparaison des differentes sources disponibles a ete effectuee. Nous en avons conclu qu'une source unitaire peut etre suffisante pour reproduire les donnees en champ lointain. En champ proche, nous nous sommes interesses au phenomene de resonances a grandes echelles. En utilisant les donnees provenant de differents instruments (maregraphiques, inclinometriques), nous avons mis en evidence le piegeage d'ondes de tsunami entre la fosse de subduction et la cote chilienne. Du fait des nombreuses sources de tsunami possible montrant des effets varies dans les differentes baies de la Polynesie francaise, une etude detaillee des modes de resonance de l'archipel des Marquises a ete effectuee contenant une discussion sur la dependance azimutale entre la position de la source et l'excitation des differentes resonances. Pour terminer, une discussion sur l'alea tsunami en France metropolitaine a ete effectuee. Suite a l'evenement recent de Boumerdes-Zemmouri (2003), le risque tsunami sur la cote mediterraneenne est connu. L'etude d'evenements supplementaires permet de mieux contraindre le risque. Moins connu, le risque tsunami sur la cote Atlantique francaise a ete etudie par la recherche d'enregistrements passes, afin de valider les simulations numeriques effectuees concernant des sources du XXe siecle. Ces modelisations permettent ainsi d'avoir une premiere analyse de l'impact de tsunamis generes dans la zone Gibraltar--Acores sur les cotes francaises.
Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics II. Identification of endosomal and lysosomal compartments in HepG2 cells combining single-step subcellular fractionation with fluorescent imaging

As they are often designed for lysosomotropic, endosomotropic and/or transcellular delivery, an understanding of intracellular trafficking pathways is essential to enable optimised design of novel polymer therapeutics. Here, we describe a single-step density gradient subcellular fractionation method combined with fluorescent detection analysis that provides a new tool for characterisation of endocytic traffic of polymer therapeutics. Hepatoma (HepG2) cells were used as a model and cell breakage was optimised using a cell cracker to ensure assay of the whole cell population. After removal of unbroken cells and nuclei, the cell lysate as a post-nuclear supernatant (PNS) was layered onto an iodixanol (OptiPrep™) density gradient optimised to 5–20%. Early endosomes, late endosomes and lysosomes were identified from gradient fractions by immunoblotting for marker proteins early endosome antigen 1 (EEA 1) and lysosomal associated membrane protein 1 (LAMP 1) using horseradish peroxidase or fluorescently-labelled secondary antibodies. Lysosomes were also detected using N-acetyl-β-glucosamindase (Hex A) activity. In addition, cells were incubated with Texas-red labelled transferrin (TxR-Tf) for 5 min to specifically label early endosomes and this was directly detected from SDS-PAGE gels. Internalised macromolecules and colloidal particles can potentially alter vesicle buoyant density. To see if typical macromolecules of interest would alter vesicle density or perturb vesicle traffic, HepG2 cells were incubated with dextran or a polyethyleneglycol (PEG)-polyester dendron G4 (1 mg/ml for 24 h). The PEG-polyester dendron G4 caused a slight redistribution of endocytic structures to lower density fractions but immunofluorescence microscopy showed no obvious dendron effects. In conclusion, the combined subcellular fractionation with fluorescent imaging approach described here can be used as a tool for both fundamental cell biology research and/or the quantitative localisation of polymer therapeutics in the endocytic pathway.
Direct Detection of Shiga Toxigenic Escherichia coliStrains Belonging to Serogroups O111, O157, and O113 by Multiplex PCR

ABSTRACT Shiga toxigenic Escherichia coli (STEC) strains are a diverse group of organisms associated with severe gastrointestinal and systemic diseases in humans. Within the STEC family,eae-positive STEC strains, particularly those belonging to serogroups O157 and O111, appear to have greater virulence for humans. However, in spite of being eae negative, STEC strains belonging to serogroup O113 have frequently been associated with cases of severe STEC disease, including hemolytic-uremic syndrome (HUS). We have developed a modified multiplex PCR assay for detection of STEC strains belonging to these three serogroups in cultures of feces by using primers specific for portions of the genetic loci (rfb) encoding biosynthesis of the respective O antigen. These primers direct amplification of PCR products of 259, 406, and 593 bp for serogroups O157, O111, and O113, respectively. The assay was validated by testing 40 previously characterized STEC strains, with 100% agreement. It also detected STEC strains of the appropriate genotype in primary fecal cultures from 13 patients with HUS or bloody diarrhea. Thirty other primary fecal cultures from patients without evidence of STEC infection were negative.
Priorities and practice in tropical paediatrics

More than 14 million children under 5 years of age die annually in the Third World, mainly due to diarrhoea, pneumonia, malaria and immunizable diseases. The problems of poverty, malnutrition, poor sanitation, illiteracy and high fertility that traditionally are associated with underdevelopment are now being compounded by social disruption due to rapid changes in lifestyle, new diseases such as AIDS and Third World debt.
Excitation, inhibition and rhythmical activity in hippocampal pyramidal cells in rabbits.

Euler, C. V. and J. D. Green. Excitation, inhibition and rhythmical activity in hippocampal pyramidal cells in rabbit. The activity pattern of single hippocampal pyramidal cells has been studied in rabbit under light urethane anaesthesia and with encephale isolein response to various stimuli. Deep depolarization leading to initial excitation followed by in-activation of spike generation has been found to be a commonly operating mechanism in the hippocampal pyramids. Such ‘inactivation processes’ have appeared spontaneously as well as in response to various stimuli. They may be driven with great precision as well as appearing rhythmically in after discharges. The ‘inactivation process’ was commonly followed by a hyper-polarization. Thus two different mechanisms of inhibition followed each other. Prolonged septal stimulation provoked trains of rhythmically recurring inactivation processes with bursts of declining spikes at the rising phase of each depolarizing wave. Close similarities between the theta rhythm and rhythmically recurring inactivation processes are described and it is suggested that the former is built up by the latter synchronously occurring in several neurones. The inactivation process was also found to be a commonly occurring cellular event during seizure activity.
Les effets proprioceptifs de la vibration artificielle du tendon d'Achille sur le mouvement de la cheville chez des pré-adolescentes gymnastes comparativement à des pré-adolescentes non gymnastes

Dans le cadre de cette recherche, nous avons etudie l'impact de la pratique de la gymnastique artistique et acrobatique sur le sens proprioceptif chez des sujets pre-adolescents gymnastes (pratiquant regulierement la gymnastique) comparativement a des sujets non-gymnastes (ne pratiquant pas regulierement cette activite). Une methode de vibration du tendon d'Achille a ete utilisee pour perturber l'information proprioceptive au cours du mouvement. L'impact de la perturbation proprioceptive a ete evalue en fonction de l'expertise des sujets en gymnastique. Les sujets devaient realiser deux tâches: une tâche statique de reproduction de mouvement de flexion dorsale et plantaire de la cheville ainsi qu'une tâche dynamique de marche, dans des conditions perturbees et non-perturbees. La precision du positionnement de la cheville dans l'espace et l'excursion angulaire au cours de la flexion dorsale et de la flexion plantaire etaient les mesures enregistrees. Les resultats en tâche statique ont demontre une tendance a l'erreur plus marquee chez les sujets gymnastes dans le positionnement final de la cheville dans l'espace. Les sujets gymnastes semblaient aussi davantage affectes par la vibration lors de la flexion dorsale de la cheville. Dans la tâche dynamique, les effets enregistres etaient minimes. Cette etude demontre que la pratique de la gymnastique modifie l'utilisation du signal proprioceptif pour les mouvements de la cheville chez des pre-adolescents. Cet effet de la pratique semble se manifester davantage pour les mouvements de precision comme le positionnement dans l'espace. ______________________________________________________________________________ MOTS-CLES DE L’AUTEUR : Proprioception, Vibration, Gymnaste, Cheville, Education physique.
Electro-thermo-rad SPICE models for SOI/SOS MOSFETs

The combined Electro-Thermo-Rad models were developed for SPICE simulation of hardened SOI/SOS CMOS ICs for aero-space applications. They account for thermal (low, high temperature, selfheating) and radiation effects (total dose, particles fluence, single heavy particles, transient ionizing radiation effects) in SPICE model of MOSFET fabricated with SOI/SOS semiconductor technologies. The models were built using macromodeling approach, standard SPICE models for MOSFETs (BSIMSOI or EKV) and model parameters dependences on temperature and radiation factors. Combined account for radiation and thermal factors in SPICE model are described for the mentioned radiation factors. The main emphasis is on combined account for TID and temperature effects in the developed model. Some examples of the Electro-Thermo-Rad models application for combined simulation of radiation and thermal effects are presented.