Miracle-dz/UniFAR-FTUs huggingface dataset:
Screening for Sleep Problems in Early Intervention and Early Childhood Special Education: A Systematic Review of Screening and Assessment Instruments

Behavioral insomnias of childhood (BIC) and sleep disordered breathing (SDB) disorders cause disrupted and/or inefficient sleep. Left untreated in early childhood, both conditions increase the risk of compromised development, particularly in the areas of behavior, cognition, and growth. This systematic review determined whether and how current developmental screening and assessment instruments (“instruments”) used in Part C Early Intervention (EI) and Part B Early Childhood Special Education (ECSE) programs of the Individuals with Disabilities and Education Act assess BIC and/or SDB. Independent abstracting teams reviewed 47 unique and 67 total (ie, includes multiple-age versions of unique) instruments. Overall, 47% of unique and 38% of total instruments contained no sleep-related items. None (0%) included any SDB items. “Resistance to bedtime,” “night waking,” and “parental concerns regarding the child's sleep” were the most frequently asked types of items. Yet, fewer than 20% of instruments addressed even these items. Among the 10 most often used instruments in EI and ECSE programs, only 40% contained BIC-type items—none asked about SDB. Given the symptom overlap between sleep problems and developmental disorders, early detection is critical. Yet, current instruments used in EI and ECSE do not adequately assess either behavioral or respiratory-related sleep disorders. Individuals with Disabilities and Education Act early childhood and related programs could serve as a portal for identifying sleep disorders.
Comparison of registration error correction techniques for air surveillance radar network

This paper considers the effectiveness of different registration algorithms in an air surveillance radar tracking environment. The evaluation is based on real data collected from an operating radar network in Canada. The existing real time quality control (RTQC) routine in the network requires targets to be on both sides of the line between the radars; this type of distribution is usually not available in the area with low air traffic density. The least squares (LS) algorithm which solves for the least squares biases is an alternative to handle this problem. Two algorithms that are considered as being more rigorous in the literature are the maximum likelihood (ML) and generalized least squares (GLS). The ML algorithm is a solution of the registration problem that uses a calculated covariance matrix of the measurement noise. The GLS algorithm is a variation of the ML algorithm where only the variances of the measurement noise are used. Based on the real data analysis, the track separation after registration are identical for the LS and ML algorithm, with the GLS being close most of the time. The result of the RTQC algorithm is close when the radar returns are split evenly between the two sides of the line between the radars. If the data in unevenly distributed, then the RTQC algorithm provides less accurate estimates. Comparing their computational complexities, the RTQC and LS algorithm are very efficient while the ML and GLS algorithm are about hundred times slower in terms of computational speed.
Multimodality in Mobile Computing and Mobile Devices: Methods for Adaptable Usability

We may not be able to make you love reading, but multimodality in mobile computing and mobile devices methods for adaptable usability will lead you to love reading starting from now. Book is the window to open the new world. The world that you want is in the better stage and level. World will always guide you to even the prestige stage of the life. You know, this is some of how reading will give you the kindness. In this case, more books you read more knowledge you know, but it can mean also the bore is full.
Improved nonlocal means method based on adaptive pre-classification for image denoising

Nonlocal Means is an effective denoising method, which takes advantage of the fact that natural image has selfsimilarity. However, the original nonlocal means may not find enough similar candidates for some non-repetitive image blocks. In order to mitigate these drawbacks, we propose an improved nonlocal means method using adaptive preclassification in this paper. The proposed method employs the threshold-based clustering algorithm to classify noisy image blocks adaptively. Then, a rotational block matching method is adopted to find the appropriate distance measurement between two blocks in an image. Experimental results on a set of well-known standard images show that the proposed method is effective, especially when the image contains large amount of noise.
Treatment outcomes for pediatric pineoblastoma: a single institute experience in Taiwan

Background: Our purpose was to evaluate the clinical outcomes of pediatric pineoblastoma patients after multimodality treatment. Methods: The medical records of 11 children with pineoblastomas treated at Taipei Veterans General Hospital between 1991 and 2006 were retrospectively reviewed. There were 7 females (63.6%) and 4 males (36.4%) with a median age at diagnosis of 5.25 years (range, 1.47–16.8 years). Age, sex, symptoms, pathological findings, treatment modalities, failure patterns, recurrence date, death date, and toxicities were recorded. Survival curves were estimated with the Kaplan-Meier method, and univariate Cox proportional hazards models were used to identify possible risk factors. Results: The median overall survival was 2.3 years, with 2- and 5-year survival rates of 63.6% and 36.4%, respectively. Eight patients (72.7%) died after serial treatments, and extensive seeding with multi-organ failure was the most common failure pattern. Three patients (27.2%) were alive without disease recurrence. Kaplan-Meier survival curves showed a significant difference (P Conclusions: Our results showed survival was associated with age at diagnosis. Long-term survival can be achieved for patients who receive radiotherapy plus chemotherapy. Further studies are needed to determine the best treatment options for pediatric pineoblastoma patients.
Design in the Visual Arts

A wheelchair for the use of invalids has two propelling wheels, at least one of which can be swung rearwardly of the seat of the chair. An armrest is provided which can be swung down, so as to be in the horizontal and permitting the user of the wheelchair to slide on the downswung armrest onto a seating or lying accommodation, the armrest being constituted by two plate elements hinged to one another, so that when unfolded the armrest offers a wide surface adapted to bridge a wide gap between the seat of the wheelchair and an accommodation to which the user of the chair transfers.
Influenza del trattamento della schizofrenia con neurolettici tipici o olanzapina sui costi sanitari e sugli outcomes lavorativi

The aim of the present study was to evaluate the global treatment cost of schizophrenia with olanzapine or typical neuroleptics, according to Local Health Care Unit point of view. This analysis was performed through naturalistic observation of a cohort of schizophrenic patients referring to Ascoli Piceno ASL Department of Mental Health during 4 years (2001-2004). During year 2003, investigators have identified a cohort of patients who were undergoing treatment switch from typical neuroleptics to olanzapine. These patients, after the switch, are observed prospectively for the next 2 years and retrospectively for the last 2 years of treament. This method allow us to collect data about 4 years of treatment: 2 years of typical neuroleptic treatment followed by 2 years of olanzapine treatment. The present work is presenting the analysis of the first 3 years of observation. The results of our analysis are demonstrating that olanzapine treatment, through a better patient-physician alliance and with rehabilitative activities, allow lower total medical costs for the treatment of schizophrenia than typical neuroleptics. The higher acquisition cost of olanzapine versus typical neuroleptics was compensated by less hospitalizations and territorial medical interventions. During olanzapine treatment patients followed more rehabilitative activities (+71,26%, p <0,0001) and increased their working activities (+39,13%, p< 0,001).
Imaging in abdominal trauma

Abdominal trauma is increasing and although penetrating wounds are also on the increase, blunt trauma remains more common. The cornerstone of management is accurate diagnosis and the advent of high-quality rapid CT scanning has revolutionised the treatment of serious abdominal injury. It has allowed the introduction of selective non-operative management which is applicable to many low- and intermediate-grade injuries, whereas application of interventional radiology can avert laparotomy in higher grade injuries. This review examines the pathophysiology of the commonest forms of abdominal injury and uses a series of cases to illustrate the impact of modern radiology in management.
Evaluation of iohexol clearance to estimate glomerular filtration rate in normal horses

In adult horses and foals, renal dysfunction can occur as a secondary complication to gastrointestinal disorders, dehydration, septicemia, endotoxemia and nephrotoxic drug administration. Measurement of renal function is an important feature not only in the diagnosis, but also in the prognosis and management of renal disease. Commonly used drugs such as phenylbutazone and gentamicin can be highly nephrotoxic under certain conditions. Estimation of the glomerular filtration rate (GFR), accepted as one of the earliest and most sensitive assessments of renal function, can be determined in horses using standard techniques such as endogenous or exogenous renal creatinine clearance. These techniques can be time consuming, dangerous to perform on fractious patients, require trained personnel and are subject to errors most often associated with improper or incomplete urine collection. Recently, tests using iohexol, a radiographic contrast agent, have been developed to estimate the GFR in human beings, pigs, sheep, dogs, cats and horse foals with results that have been validated by traditional standards.
Informatique en éducation : perspectives curriculaires et didactiques

Qu’en est-il actuellement de l’enseignement du numerique ou plutot de l’informatique et des technologies qui en procedent ? A bien des egards, la periode actuelle est celle de la transition entre deux epoques. Dans la precedente (depuis les annees 1990) il suffisait, au moins dans l’enseignement general, de considerer la familiarisation avec des outils, en se fondant sur une approche par competences. La seconde, dans laquelle nous semblons entrer, est celle de la prise de conscience de la necessite a transmettre aux jeunes generations les elements d’une culture. Mais laquelle ? Cela fait l’objet de debats nombreux, auxquels cet ouvrage a pour ambition d’apporter un eclairage singulier. Les contributions qu’il presente, fondees sur des recherches en didactique de l’informatique, suggerent qu’il est possible de transmettre, meme a des non-scientifiques, des elements leur permettant de faire comprendre a de jeunes enfants des notions liees a la programmation et a des algorithmes tres simples. Mais quels savoirs transmettre a tous, comment les organiser sous forme de curricula ? Cette question, critique, est bien entendu politique et ne peut etre resolue par la seule recherche. Mais cette derniere a pour responsabilite d’analyser la situation, de la situer par rapport a celle d’autres pays et de suggerer des pistes de solutions possibles. En mettant a disposition des lecteurs francophones des textes et l’experience d’acteurs majeurs a l’echelle internationale, cet ouvrage, qui vise un large public, a pour ambition modeste de planter un jalon en diffusant des resultats de recherche recents.
Intraoperative visualization of the tumor microenvironment and quantification of extracellular vesicles by label-free nonlinear imaging

Intraoperative imaging of tumor microenvironment reveals correlations between extracellular vesicle density and breast pathology. Characterization of the tumor microenvironment, including extracellular vesicles (EVs), is important for understanding cancer progression. EV studies have traditionally been performed on dissociated cells, lacking spatial information. Since the distribution of EVs in the tumor microenvironment is associated with cellular function, there is a strong need for visualizing EVs in freshly resected tissues. We intraoperatively imaged untreated human breast tissues using a custom nonlinear imaging system. Label-free optical contrasts of the tissue, correlated with histological findings, enabled point-of-procedure characterization of the tumor microenvironment. EV densities from 29 patients with breast cancer were found to increase with higher histologic grade and shorter tumor-to-margin distance and were significantly higher than those from 7 cancer-free patients undergoing breast reduction surgery. Acquisition and interpretation of these intraoperative images not only provide real-time visualization of the tumor microenvironment but also offer the potential to use EVs as a label-free biomarker for cancer diagnosis and prognosis.
Energy-efficient MFCC extraction architecture in mixed-signal domain for automatic speech recognition

This paper proposes a novel processing architecture to extract Mel-Frequency Cepstrum Coefficients (MFCC) for automatic speech recognition. Inspired by the human ear, the energy-efficient analog-domain information processing is adopted to replace the energy-intensive Fourier Transform in conventional digital-domain. Moreover, the proposed architecture extracts the acoustic features in the mixed-signal domain, which significantly reduces the cost of Analog-to-Digital Converter (ADC) and the computational complexity. We carry out the circuit-level simulation based on 180nm CMOS technology, which shows an energy consumption of 2.4 nJ/frame, and a processing speed of 45.79 μs/frame. The proposed architecture achieves 97.2% energy saving and about 6.4× speedup than state of the art. Speech recognition simulation reaches the classification accuracy of 99% using the proposed MFCC features.
Generalized Eilenberg Theorem

For finite automata as coalgebras in a category C, we study languages they accept and varieties of such languages. This generalizes Eilenberg’s concept of a variety of languages, which corresponds to choosing as C the category of Boolean algebras. Eilenberg established a bijective correspondence between pseudovarieties of monoids and varieties of regular languages. In our generalization, we work with a pair C/D of locally finite varieties of algebras that are predual, i.e., dualize on the level of finite algebras, and we prove that pseudovarieties of D-monoids bijectively correspond to varieties of regular languages in C. As one instance, Eilenberg’s result is recovered by choosing D = sets and C = Boolean algebras. Another instance, Pin’s result on pseudovarieties of ordered monoids, is covered by taking D = posets and C = distributive lattices. By choosing as C amp;equals; D the self-predual category of join-semilattices, we obtain Polák’s result on pseudovarieties of idempotent semirings. Similarly, using the self-preduality of vector spaces over a finite field K, our result covers that of Reutenauer on pseudovarieties of K-algebras. Several new variants of Eilenberg’s theorem arise by taking other predualities, e.g., between the categories of non-unital Boolean rings and of pointed sets. In each of these cases, we also prove a local variant of the bijection, where a fixed alphabet is assumed and one considers local varieties of regular languages over that alphabet in the category C.
Local persistence of Mann’s soft-haired mouse Abrothrix manni (Rodentia, Sigmodontinae) during Quaternary glaciations in southern Chile

Quaternary climatic oscillations have impacted Patagonian sigmodontine fauna, leaving traceable genetic footprints. In southern Chile, changes in the landscape included transitions to different vegetation formations as well as the extension of ice sheets. In this study, we focus on the Valdivian forest endemic and recently described sigmodontine species Abrothrix manni. We aim to assess the genetic structure of this species, testing for the existence of intraspecific lineages, and inferring the recent demographic history of the species. Analyses were based on the first 801 bp of the mitochondrial gene Cytocrhome-b from 49 individuals of A. manni collected at 10 localities that covers most part of its geographic distribution. Genealogical analyses recovered two main intraspecific lineages that are geographically segregated and present an intermediate site of secondary contact. Historical demography shows signal of recent population decrease. Based on these results, we proposed that current genetic diversity of A. manni differentiated in at least two distinct refugial areas in southern Chile. This scenario, in addition to be unique among those uncovered for the so far studied Valdivian forest rodents, is noteworthy because of the reduced geographic scale inhabited by the species.
Comparison of efficacy and safety between two different irbesartan, generic vs branded, in the treatment of Korean patients with mild-to-moderate hypertension: an 8-week, multicenter, randomized, open-label, Phase IV clinical study

Purpose This study aimed to compare the efficacy and safety of generic and branded irbesartan for 8 weeks in patients with mild-to-moderate essential hypertension. Patients and methods We screened 221 patients with mild-to-moderate hypertension. After exclusion per study criteria, 177 subjects were randomized to receive 150 mg generic irbesartan (n=91) or branded irbesartan (n=86) as the intention to treat set. The primary efficacy endpoint of this study was the change in mean sitting diastolic blood pressure (SiDBP) from baseline to 8 weeks between the generic and branded irbesartan groups. The secondary efficacy endpoints were the change in mean SiDBP at Week 4 from baseline and the change in mean sitting systolic blood pressure (SiSBP) at Weeks 4 and 8 from baseline in both groups. All safety issues were evaluated. Results At Week 8, the generic and branded irbesartan groups showed significantly reduced SiDBP (-10.3±8.0, -10.7±7.7 mmHg, all P<0.0001) compared with baseline values, and the mean between-group difference in SiDBP change after 8 weeks of treatment was -0.4±1.2 mmHg, showing the non-inferiority of generic irbesartan vs branded irbesartan. Furthermore, secondary efficacy, which was the mean change of SiDBP from baseline at 4 weeks, was comparable between the two groups (-9.4±8.1 vs -9.9±7.4 mmHg, P=0.69). There were no between-group differences in mean changes of SiSBP after 4 or 8 weeks of treatment (P=0.78, P=0.97, respectively), or in the incidence of adverse effects (16.7 vs 24.4%, P=0.20). Conclusion Generic irbesartan treatment in patients with mild-to-moderate essential hypertension has shown effective antihypertensive effects comparable with the branded irbesartan treatment, with similar incidence of adverse effects.
Factors associated with carotid intima-media thickness in patients on maintenance hemodialysis

Purpose The aim of this study was to analyze the association of the carotid intima-media thickness (CIMT) with various parameters in patients on maintenance hemodialysis (mHD). Methods A cross-sectional study was conducted, enrolling 68 subjects (41 men, 27 women) on mHD in the Hemodialysis Unit, Sanglah Hospital, Denpasar, Indonesia. CIMT was measured with B-mode ultrasonography using a USG Sonoace 8000 and a 7.5 MHz linear transducer. Results CIMT was higher in subjects with cardiovascular disease (CVD) compared with those without CVD (0.6494 vs 0.7288 mm; P=0.026), and in men compared with women (0.7056 vs 0.6141 mm; P=0.003). CIMT was correlated with age (R=0.607; P<0.001), plasma albumin (R=−0.291, P=0.016), serum phosphate (R=−0.294, P=0.015), calcium-phosphate product (R=−0.284, P=0.011), and plasma high-sensitivity C-reactive protein (R=0.279, P=0.030). However, after multiple linear regression testing, only age consistently had a role in determining the CIMT value (β=0.452, P<0.001). Conclusion Subjects with CVD have higher CIMT than those without CVD and men had higher CIMT than women. In addition, older age, higher high-sensitivity C-reactive protein, and lower albumin, phosphate, and calcium-phosphate product levels were correlated with higher CIMT. Age was the most important marker for CIMT in subjects on mHD.
"Muddily human" : antimodernism in the novels of Robert Kroetsch

For many years the novels of Robert Kroetsch have been canonized as paradigmatic Canadian postmodern and postcolonial texts. This thesis argues that Kroetsch’s texts are antimodernist works which reveal his reaction against modernity. This thesis explores each of Kroetsch’s novels in chronological order, from the unpublished text When Sick for Home to his most recent novel The Man from the Creeks, arguing that Kroetsch’s novels should be viewed as texts that demonstrate his antipathy towards modernity, which is manifested in Kroetsch’s nostalgic idealization of the imagined organic wholeness of a world existing prior to modernization. Throughout this thesis I discuss the parallels between the writings of Robert Kroetsch and Marshall McLuhan, emphasizing the antimodernism that underpins their works. I argue that their antimodernism signals their participation in a tradition of the critique of modernity. By foregrounding the idea of the modernist critique of modernity, which comprises an important element of artistic modernism, I question the privileging of the qualifier “post-” in constructions of the Canadian postmodern canon. In foregrounding the antimodernism evident throughout Robert Kroetsch’s fiction, I interrogate the construction of Canadian postmodernism in his own works and those of other Canadian critics including Linda Hutcheon. Through my analysis of the recurring motifs of the wilderness and the rural environment in Kroetsch’s work, I locate his fiction within Western antimodernist tradition, interrogating cultural nationalist constructions of Canadian postmodernism as an autochthonous phenomenon.
Upregulation of circulating miR130a is correlated with development of Barrett’s esophagus and esophageal adenocarcinoma

Background Barrett’s esophagus (BE) is one of the major known risk factors for esophageal adenocarcinoma (EAC). Circulating miRNAs are emerging as predictive biomarkers for early detection of malignancy. However, the potential for circulating miRNAs to be used as biomarkers for BE neoplastic progression to EAC has not been well characterized. Method We performed a systematic screening approach to identify spectrum miRNAs in the serum of both BE and EAC patients. Results miRNA-array web-based software identified 116 sequences differentially expressed between BE patients and healthy controls. Subsequent study revealed that miR130a was significantly upregulated in serum samples of BE and EAC patients compared to healthy controls. We found an increase in serum miR130a in low-grade and high-grade dysplasia BE patients compared to individuals with metaplasia. We also observed that miR130a expression levels increased gradually from early-stage (I, II) to advanced-stage (III, IV) EAC patients. Conclusion Our preliminary results provide evidence that circulating miR130a is correlated with the development of BE and EAC.