Miracle-dz/UniFAR-FTUs huggingface dataset:
Sleep Quality and Lower Urinary Tract Symptoms Among Patients with Prostatic Diseases

Background: Incidence of symptomatic prostatic diseases increases with age. Nocturia disturbs sleep. We set out to determine the quality of sleep and severity of lower urinary tract symptoms (LUTS) and bother score in patients with benign prostatic hyperplasia (BPH) and carcinoma of the prostate (CAP). Methods: A cross-sectional study of new patients seen in the urology outpatient clinic with bladder outlet obstruction (BOO) from either BPH or CAP over a period of 18 months. Patients were interviewed using Pittsburgh Sleep Quality Index (PSQI) and International prostate symptoms score (IPSS) questionnaires. Data obtained were analyzed using SPSS version 23. Results:168 patients were interviewed. CAP patients were older than their BPH counterparts. About 45% of the patients had poor sleep quality. CAP patients (52.9%) were more of poor sleepers compared with BPH patients (40.0%). CAP patients (46.3%) had more severe IPSS than BPH patients (33.3%). Both CAP (70.6%) and BPH (76.0%) patients reported high bother score. Conclusion: CAP and BPH patients have high bother score, affirming need for early treatment. CAP patients had more severe lower urinary tract symptoms and poorer sleep quality than BPH patients. Keywords: IPSS, Sleep quality, LUTS, Bother score
Interfacial Behavior of Egg Yolk with Reduced Cholesterol Content

The interfacial activity of low-cholesterol yolk protein concentrates, prepared by treating spray-dried yolk with various extraction media, was investigated using the Wilhelmy plate method. The rate of interfacial pressure increase and the equilibrium value reached after 4 h of adsorption were influenced by the method of extraction applied, indicating that, in addition to composition changes, structural alterations in yolk protein structure brought about by the extraction determine to some extent their adsorption behavior. The presence of surface-active constituents, i.e., monoglycerides, diglycerides, and phospholipids, in vegetable oil also affected the interfacial pressure value of adsorbed yolk films, possibly the result of interactions between the yolk and the oil surface-adsorbing molecules at the oil−water interface. Keywords: Egg yolk; cholesterol; interfacial pressure; adsorption
Effect of prebiotic fructans and organic acids on mineral retention in laying hens

Abstract The aim of the study was to evaluate the effect of organic acids and prebiotic fructans added to the layer's diet on balance of calcium, phosphorus, and zinc. The basal experimental diet contained 3.30% Ca and 0.60% P, and was either unsupplemented or supplemented with additives as follows: 0.75% inulin, 0.75% oligofructose; 0.50% short-chain fatty acids (SCFA); 0.25% medium-chain fatty acid (MCFA); 0.30% SCFA+0.20% MCFA; and 0.75% inulin+0.50% SCFA. It was concluded that some additives used in the experiment had a positive effect on the mineral balance in hens. Inulin significantly improved retention of Ca, P, and Zn, SCFA – retention of Ca, SCFA+MCFA – retention of Zn, inulin+SCFA – retention of P and Zn.
Stable carbon and nitrogen isotope patterns in baleen from eastern Arctic bowhead whales (Balaena mysticetus)

Previous measurements of naturally occurring stable isotopes of carbon (delta13C) and nitrogen (delta15N) along the baleen plates of western Arctic bowhead whales (Balaena mysticetus) have provided a continuous lifetime record of the feeding or nutritional ecology of these animals that migrate annually between isotopically different foodwebs. However, virtually nothing was known about isotopic patterns of eastern Arctic bowheads. We measured delta13C and delta15N values along the baleen plates of three eastern and one western Arctic bowhead whales taken from Canadian waters in 1988 and 1996. In contrast to western Arctic animals, we found strong evidence for periodic fluctuations in delta15N but not delta13C values in the eastern Arctic specimens. We interpret these results as evidence that eastern Arctic animals do not move between foodwebs that differ in delta13C signature and suggest that these whales either (i) move annually between areas isotopically enriched in 15N but not 13C, (ii) shift diet annua.
Flavonol Glycosides from Erica cinerea

In addition to quercetin 3-rutinoside [1], isorhamnetin 3-rutinoside [2], and myricetin 3-rutinoside [3], a new flavonol glycoside was isolated from fresh heather flowers of Erica cinerea. Its structure was established as gossypetin 3-[α-L-rhamnopyranosyl (1→6) β-D-glucopyranoside] [4] by spectroscopic analysis
Mode Awareness and Automated Driving - What Is It and How Can It Be Measured?

In SAE (Society of Automotive Engineers) Level 2, the driver has to monitor the traffic situation and system performance at all times, whereas the system assumes responsibility within a certain operational design domain in SAE Level 3. The different responsibility allocation in these automation modes requires the driver to always be aware of the currently active system and its limits to ensure a safe drive. For that reason, current research focuses on identifying factors that might promote mode awareness. There is, however, no gold standard for measuring mode awareness and different approaches are used to assess this highly complex construct. This circumstance complicates the comparability and validity of study results. We thus propose a measurement method that combines the knowledge and the behavior pillar of mode awareness. The latter is represented by the relational attention ratio in manual, Level 2 and Level 3 driving as well as the controllability of a system limit in Level 2. The knowledge aspect of mode awareness is operationalized by a questionnaire on the mental model for the automation systems after an initial instruction as well as an extensive enquiry following the driving sequence. Further assessments of system trust, engagement in non-driving related tasks and subjective mode awareness are proposed.
Meat quality of heifers fattened to heavy weights to enhance marbling

Marbling is the primary factor affecting quality grades of youthful grain-fed cattle in the Canadian, American and Japanese grading systems. Cattle were fed for an extended period of time and to extreme slaughter weights to enhance marbling. The effects of slaughter weight, breed, nutrition, and grading site (12/13th rib-Canadian or 6/7th rib-Japanese) on meat quality were evaluated using 221 weaned heifer calves (exp. 1) and 216 yearling heifers (exp. 2) raised on high (HP) or moderate-high (MHP) planes of nutrition. Mean intramuscular fat concentration in longissimus muscle was 6.93, 8.94, and 9.86% at mean slaughter weights of 500, 590, and 680 kg, respectively (exp 1) and 6.84% and 9.02% at 590 and 680 kg (exp. 2). HP carcasses had more intramuscular fat and lower shear values and drip losses than MHP carcasses (P ≤ 0.05). Angus carcasses had more intramuscular fat and lower shear values than the other breeds studied. Holsteins on the HP diet produced tender meat with a high amount of intramuscular fa.
Incidence of HCC recurrence after DAA treatment for HCV in a multicentre Italian cohort study

The present real‐life multicentre, prospective study aims to investigate the effects of direct‐acting antivirals (DAAs) in HCV patients with a previous successfully treated hepatocellular carcinoma (HCC), in terms of neoplastic recurrence and sustained virological response (SVR) rates.
Navigating complexity: The importance of design-based research for faculty development

Abstract Despite the importance of evidence-based medical education, navigating the complexity of its implementation can be frustrating. Faculty development that engages and supports medical educators in Design-Based Research is one promising approach to respond to this challenge. An essential aspect of this process is to expand faculty’s Zone of Generativity and thus foster their individual and collective capabilities to navigate the complexity of implementing evidence-based medical education.
The effects of nitrogen nutrition of plants on the development of acidity in Western Australian soils. I: Effects with subterranean clover grown under leaching conditions

Subterranean clover was grown, under leaching conditions, in pots on cultivated and virgin acidic sandy soils from two sites in Western Australia. Nitrogen (N) was supplied to the plants either as NH+4, NO-3 or through symbiotic fixation. There were marked changes in the acidity of the soil as the result of the differences in catiot/anion balance induced by the different forms of N supplied. Thus plants supplied with NH+4 depressed the pH by 0.9 pH units, and those dependent upon fixation by 0.5 pH units. There was little change in pH when NO-3 was supplied. Changes in soil pH were strongly related to cation/ anion balance, with increasing acidity resulting from the decreasing ash alkalinity of shoots of plants supplied with NH+4. There were marked differences both between the two soils from the same site, as well as between soils from the two different sites, in the relationships between pH and soluble aluminium and pH and exchange acidity. It is suggested that differences in the form, as well as differences in the total amount, of organic matter could play a major role in controlling the development of acidity in such soils of low, permanent cation exchange capacity.
Does knowledge management boost wages in large and medium-sized Serbian companies?

U ovoj studiji se analizira uticaj menadžmenta znanja na poslovne varijable velikih i srednjih kompanija u Srbiji. Istraživanje se oslanja na Romerovu teoriju o endogenom znanju kao osnovi za stabilan rast. U svrhu istraživanja, kreiran je dataset za merenje menadžmenta znanja koji sadrži 11 varijabli svrstanih u pet tematskih celina: akademsko obrazovanje, obuka zaposlenih, skladištenje, diseminacija znanja i tehnička podrška. Cilj istraživanja jestedase potvrdiuticaj dataseta na prosečnu mesečnu platu zaposlenih u kompanijama. Korišćenjem upitnika sa zatvorenim odgovorima, intervalskim i Likertovim lestvicama, intervjuisani su menadžeri 126 kompanija. Putem faktorske analize, izolovanasu četiri složena faktorska skora, koji predstavljaju strategije koje kompanije koriste i kombinuju u upravljanju znanjem. Na osnovu rezultata ordinalne regresione analize, sprovedene u velikim kompanijama na nivou privrede, set od četiri nezavisne prediktorske varijable objašnjava 69% varijabilnosti zavisne varijable „prosečna plata zaposlenih u kompaniji”. U slučaju srednjih kompanija, koeficijent R2 je veći i iznosi 74.4%. Kada je reč o velikim i srednjim industrijskim kompanijama, primetno je da menadžment forsira strategiju ulaganja u obuku zaposlenih na seminarima, finansiranje pretplate za pristup virtuelnim bibliotekama i bazama znanja, kao i organizovanje procedure skladištenja znanja. Menadžment ovih kompanija takođe nastoji da među zaposlenima ima najveći mogući procenat eksperata sa master i fakultetskim diplomama.
Virulence studies of Salmonella enteritidis phage types

Salmonella enteritidis phage types (PTs) 8, 13a and 24 could be distinguished by their virulence for BALB/c mice, their plasmid content and plasmid fingerprint. Virulent strains expressed long‐chain lipopolysaccharide and carried a 38 MDa plasmid indistinguishable from that in Salm. enteritidis PT 4. Avirulent strains were smooth but did not carry the 38 MDa plasmid. Possession of antibiotic resistance factors by some strains of Salm. enteritidis PT 24 did not contribute to the virulence of their host strains.
NUMERICAL RESPONSE OF COCCINELLIDS TO APHIDS IN CORN IN SOUTHERN ONTARIO

Abstract Populations of two abundant coccinellid species, Coleomegilla maculata lengi Timberlake and Hippodamia tredecimpunctata tibialis Say, responded rapidly to corn leaf aphid populations [Rhopalosiphum maidis (Fitch)] once the aphids became exposed to predation when the plants tasselled. Coleomegilla m. lengi oviposited at lower densities of aphids than did H. t. tibialis but H. t. tibialis was shown to have a greater numerical response than C. m. lengi at high densities of aphids due to its greater fecundity. The numerical response of the coccinellids by oviposition was linear with a lag of 1/2 week behind the aphid population. Résumé Les populations de deux espèces abondantes de coccinelles, Coleomegilla maculata lengi Timberlake et Hippodamai tredecimpunctata tibialis Say, ont répondu rapidement aux populations du puceron du maïs [Rhopalosiphum maidis (Fitch)] une fois que les pucerons devinrent exposés à la prédation lors de la sortie de la panicule. C. m. lengi a pondu à des densités de pucerons plus faibles que H. t. tibialis, cependant H. t. tibialis a montré une réponse numérique plus forte que C. m. lengi aux densités élevées de pucerons, dû à sa fécondité plus élevée. La réponse numérique de ponte des coccinelles s’est révélée linéaire avec un retard d’une demi-semaine sur la population de pucerons.
Mechanisms underlying amphipod responses to zebra mussel (Dreissena polymorpha) invasion and implications for fish-amphipod interactions

We examined mechanisms underlying increased amphipod abundance after zebra mussels (Dreissena polymorpha) invaded Lake Erie. We conducted field substrate preference experiments to test the hypotheses that amphipods prefer (i) high-complexity substrates over low-complexity substrates and (or) (ii) substrates with high mussel feces and pseudofeces deposition over substrates with low deposition. We measured amphipod preference for bare rock, live mussels, and dead mussels in spring (May 1996) and summer (July and August 1995, June and August 1996). Habitat complexity affected amphipod habitat preference, and preference varied seasonally. In spring, amphipod density was highest on dead mussels, but the response was highly variable. In midsummer (June and July), amphipods showed no substrate preference. In late summer (August), amphipods consistently preferred high-complexity mussel substrates. Amphipods never preferred low-complexity substrates. We also evaluated effects of zebra mussel presence on fish-amphi.
Improved preservation and staining of HeLa cell actin filaments, clathrin-coated membranes, and other cytoplasmic structures by tannic acid-glutaraldehyde-saponin fixation

Fixation of HeLa cells with a mixture of 100 mM glutaraldehyde, 2 mg/ml tannic acid and 0.5 mg/ml saponin allows the tannic acid to penetrate intact cells without disruption of membranes or extraction of the cytoplasmic matrix. After subsequent treatment with OsO4 cytoplasmic structures are stained so densely that fine details are visible even in very thin (dark gray) sections. Actin filaments are protected from disruption by OsO4 so that straight, densely stained filaments are seen in the cell cortex, filopodia, ruffling membranes, and stress fibers. Stress fibers also have 15-18-nm densities similar in appearance to myosin filaments. Tannic acid staining reveals that the coats of coated vesicles, pits, and plaques have a 12-nm layer of amorphous material between the membrane and the clathrin basketwork. HeLa cells have very large clathrin-coated membrane plaques on the basal surface. These coated membrane plaques appear to be a previously unrecognized site of cell-substrate adhesion.
Salt‐induced expression of peroxisome‐associated genes requires components of the ethylene, jasmonate and abscisic acid signalling pathways

Peroxisomes participate in many biological functions including detoxification of reactive oxygen species and biosynthesis of oxylipin signalling molecules. Peroxisome protein and enzyme activities have been reported to change in response to salt stress. To investigate the relationship between peroxisomes and salt stress the level of expression of three peroxisome-associated genes, thiolase ( PED1 ), PEX10 and PEX1 was analysed by quantitative real-time polymerase chain reaction. The steady-state transcript level of all three genes was increased by salt and ABA treatment, and was blocked in the abi1-1 mutant. Salt-dependent increase of transcript for all three genes also required the JAR1 gene as it was prevented in the jar1-1 mutant. Expression of thiolase, and to a lesser extent PEX1 , was increased in the jar1-1 mutant in the absence of salt, suggesting jasmonate may negatively regulate these genes in the absence of salt stress. PEX1 was up-regulated in the ethylene over-producer eto1-1 and salt had an additive effect on PEX1 transcript level, but salt induction may be inhibited in the ethylene-insensitive line etr1-1 . Consistent with this, PEX1 was also up-regulated in transgenic plants over-expressing the ethylene response element binding factors AtERF1 and AtERF5.
Evaluating Ultraviolet Radiation Exposure with Satellite Data at Sites of Amphibian Declines in Central and South America

Abstract: Many amphibian species have experienced substantial population declines or have disappeared altogether during the last several decades at a number of amphibian survey sites in Central and South America. Our study addresses the use of trends in solar UV‐B radiation exposure (280–320 nm) at these sites over the last two decades, derived from the Total Ozone Mapping Spectrometer satellite data. It is intended to demonstrate a role for satellite observations in determining whether UV‐B radiation is a contributing factor in amphibian declines. We used these data to calculate the daily erythemal (sunburning) UV‐B, or UV‐Bery , exposure at the latitude, longitude, and elevation of each of 20 survey sites. The annually averaged UV‐Bery dose, as well as the maximum values, have been increasing in both Central and South America, with higher levels reached at the Central American sites. The annually averaged UV‐Bery exposure increased significantly from 1979–1998 at all 11 Central American sites we examined (r 2 = 0.60–0.79; p≤ 0.015), with smaller but significant increases at five of the nine South American sites (r 2 = 0.24–0.42; p≤ 0.05). The number of days having the highest UV‐B exposure (≥6.75 kJ/m2/day) increased in both regions from <40 days per year to approximately 58 days per year in 1998 (r2 = 0.24–0.42; p≤ 0.001). In Central America, the contribution of these very high UV‐Bery exposure levels to the annual UV‐Bery total increased from approximately 5 to approximately 15% over the 19‐year period, but actual daily exposures for each species are unknown. A UV‐B ratio, the highest monthly UV‐B exposure relative to the annual average for the highest UV‐B category (≥6.75 kJ/m2), increased in both regions over this time period (r 2 = 0.73; p≤ 0.001). This UV index was consistently higher for Central America, where species declines have been the most severe. These results should justify further research into whether UV‐Bery radiation plays a role in amphibian population declines and extinctions. We discuss synergy among UV‐B radiation and other factors, especially those associated with alterations of water chemistry (e.g., acidification) in aqueous habitats.
Adresser du matériel allogène dans le compartiment mitochondrial - Un défi pour comprendre la physiologie mitochondriale et une perspective pour la thérapie

Mitochondrial disorders can not be ignored anymore in most medical areas. They include specific and widespread organ involvement, with tissue degeneration or tumor formation, being the target of numerous viruses, e.g. the HIV. Primary or secondary actors, mitochondrial dysfunctions are also supposedly playing a role in the ageing process. Despite the progresses made in the identification of their molecular bases, nearly all remains to be done as regards therapy. Research dealing with mitochondrial physiology and pathology has a long history in France and is thus not a surprise if four French teams, coming from these fundamental domains, are involved in the challenge to find ways to fight these diseases. The directions described are working tracks which promise to be long and full of pitfalls. Being original, they share a part of risk and uncertainty, but they are also with great potential with high stakes if considering the impact of these diseases.
Olfactory Perception in Migrating Salmon: III. Stimulants for Adult Sockeye Salmon (Oncorhynchus nerka) in Home Stream Waters

Adult sockeye salmon (Oncorhynchus nerka) captured during their spawning migration to Great Central Lake, British Columbia, show a consistent response in the laboratory to water taken from the outlet of the lake. The specificity of this response has been confirmed and the responses to water from streams feeding Great Central Lake have been determined. A portion at least of the stimulatory material is volatile and can be retained in a cold trap. Concentration of the active factor has been achieved by a freezing-out technique.
Effects of photostimulatory lighting and feed allocation in female broiler breeders 1. Reproductive development

Changes in carcass traits during sexual maturation were studied with female Shaver Starbro breeders in a 2 × 2 factorial design with two lighting programs and two feeding programs. Pullets were individually caged in a light tight facility at 20 wk of age. The light period of fast photoperiod (FP) hens was changed from 8L:16D to 15L:9D at 20 wk of age. Slow photoperiod (SP) hens were switched from a 8L:16D photoperiod at 20 wk to 11L:13D, with increases to 12L:12D, 13L:11D, 14L:10D, and 15L:9D weekly to 24 wk of age. Slow feed (SF) hens were given small (5 g or less) weekly increases in feed allocation from 20 to 25 wk. Fast feed (FF) hens received larger feed allocations than the SF birds from 20 to 25 wk (maximum difference of 25 g more feed than SF hens received). Birds were processed at weekly intervals between 20 and 26 wk of age (Group A) or at sexual maturity (Group B), which was considered to be the day of the first oviposition.Age at sexual maturity did not differ due to photostimulation or feedin.
Study and management of type-2 diabetes mellitus in patients with hypertension at tertiary care hospital

Background: This study was aimed to study and management of hypertension in diabetic patients. Methods: A prospective, observational study was conducted in 160 diabetic hypertensive patients admitted in general medicine wards at Andhra Pradesh Vaidya Vidhana Parishad Hospital, (APVVP), Proddatur. Patients who signed informed consent form were only included in the study. All the data were recorded from patients’ case files and analyzed. Results: Of enrolled 160 patients, 86 (53.75%) were female and 74 (46.25%) were male and maximum number of the patients 32.5% were found in the age group of 60-69 years. Out of 160 admitted patients, 51 patients treated with metformin, glibenclamide and atenolol, 18 patients treated with metformin, glimiperide, and amlodipine, 6 patients treated with metformin and amlodipine, 28 patients treated with metformin, glimiperide and atenolol, 19 patients treated with metformin and atenolol, 17 patients treated with metformin, glibenclamide and amlodipine, 9 patients treated with metformin, glibenclamide and losartan, 5 patients treated with metformin and losartan, 7 patients treated with metformin, glimiperide, and losartan. Conclusions: There was less awareness among the patients regarding the control of type-2 diabetes mellitus with hypertension. Majority of diabetic patients noticed with hypertension and β adrenergic blockers remained first choice of drug for hypertension in diabetes. Calcium channel blockers were also prescribed to many patients and were successful to achieve target blood pressure. Among anti-diabetic drugs, biguanides were most frequently prescribed class of drugs. Metformin was the most prescribed drug and Sulphonyl urea were the next most prescribed class of