Miracle-dz/UniFAR-FTUs huggingface dataset:
Environmental Application of Agro-waste Derived Materials for the Treatment of Dye-polluted Water: A Review

The extensive industrialization and unrestricted development of dyeutilizing industries coupled with the shortage of proper effluent treatment methods have increased the water pollution. Disposal of dyes in a natural water system is a severe worldwide concern owing to the harmful effects on the ecosystem. Among the available wastewater treatment methods, adsorption is considered as a promising alternative in the elimination of dyes. There are a variety of ways for the modification of agro-waste, such as (i) acid modification (ii) alkali modification, (iii) surfactant modification, and (iv) preparation of activated carbon, etc. Moreover, numerous techniques have been used for the characterization of modified agro-waste, such as, SEM/EDAX, TEM, BET, TGA, and FTIR. From the literature study, it was observed that the adsorption efficiency of various modified agro-waste is reliant on the nature of the adsorbent materials and different batch parameters, such as initial dye concentration, solution pH, adsorbent dose, and temperature of the system. In this way, these components must be thought about while evaluating the elimination of dye using various agrobased adsorbents. Modification of agricultural waste usually improved the adsorption capacity of adsorbents due to an escalation in the number of active adsorbing sites, enhancement in the porosity, increase in the surface area, and generation of new functional groups that favor the removal of dye from wastewater. Agro-waste materials being inexpensive, abundant, and renewable can be effectively exploited for the confiscation of dye from aqueous media.
Performance Modeling of Softwarized Network Services Based on Queuing Theory With Experimental Validation

Network Functions Virtualization facilitates the automation of the scaling of softwarized network services (SNSs). However, the realization of such a scenario requires a way to determine the needed amount of resources so that the SNSs performance requisites are met for a given workload. This problem is known as resource dimensioning, and it can be efficiently tackled by performance modeling. In this vein, this paper describes an analytical model based on an open queuing network of G/G/m queues to evaluate the response time of SNSs. We validate our model experimentally for a virtualized Mobility Management Entity (vMME) with a three-tiered architecture running on a testbed that resembles a typical data center virtualization environment. We detail the description of our experimental setup and procedures. We solve our resulting queueing network by using the Queueing Networks Analyzer (QNA), Jackson's networks, and Mean Value Analysis methodologies, and compare them in terms of estimation error. Results show that, for medium and high workloads, the QNA method achieves less than half of error compared to the standard techniques. For low workloads, the three methods produce an error lower than 10 percent. Finally, we show the usefulness of the model for performing the dynamic resource provisioning of the vMME experimentally.
Management von schwerwiegenden intrazerebralen Blutungen unter Antikoagulation

Zusammenfassung Die Inzidenz der intrazerebralen Blutung unter oraler Antikoagulation (OAK-ICB) steigt aufgrund der demografischen Entwicklung und der daraus resultierenden Zunahme an Patienten, die bei einem Vorhofflimmern antikoaguliert werden. Die OAK-ICB stellt eine der schwerwiegendsten Formen des hämorrhagischen Schlaganfalls dar, ist charakterisiert durch größere Blutungsvolumina, vermehrten Ventrikeleinbruch sowie häufigere und prolongierte Nachblutungen. Der Einfluss dieser Prognoseparameter mündet schließlich in eine erhöhte Sterblichkeit und ein hohes Maß an bleibender funktioneller Beeinträchtigung. Doch gerade bei diesem schweren Erkrankungsbild fehlt meist eine belastbare Evidenz, sodass die aktuellen internationalen und europäischen Leitlinien häufig nur schwache Therapieempfehlungen abgeben können. Im Rahmen der Akutbehandlung einer OAK-ICB ist das Hauptziel eine Minimierung der Hämatomprogression, welche durch Blutdruck- und Gerinnungsmanagement möglicherweise erreicht werden kann. Für alle OAK-ICBs erscheint die sofortige und aggressive Blutdrucksenkung auf einen systolischen Zielwert von 140 mmHg (mind. innerhalb von 4 – 6 Stunden) nach Aufnahme sinnvoll und für intrazerebrale Blutungen unter Vitamin-K-Antagonisten konnte eine Assoziation mit einer reduzierten Nachblutungsrate aufgezeigt werden. Die Antagonisierung der OAK-ICB sollte immer so rasch wie möglich, aber in Abhängigkeit von der jeweiligen oralen Antikoagulation erfolgen. Für die Vitamin-K-Antagonisten assoziierte ICB konnten große multizentrische Arbeiten in den letzten Jahren beitragen ein präziseres Vorgehen zu definieren. In Rahmen einer deutschlandweiten Kohortenstudie an knapp 1200 OAK-ICB (unter Marcumar bzw. Falithrom) konnten erstmals konkrete Zielwerte identifiziert werden. Eine Antagonisierung sollte mindestens bis zu einem INR-Wert < 1,3 bzw. 1,2 mindestens innerhalb von 4 Stunden nach Aufnahme erfolgen. Mittel der Wahl sollten Prothrombinkomplexkonzentrate (PPSB) sein, um eine rasche und vollständige Antagonisierung zu erzielen. Durch dieses kombinierte Procedere konnte eine deutliche Minimierung der Hämatomwachstumsraten und eine reduzierte Krankenhaussterblichkeit verzeichnet werden. Seit kurzem steht für Dabigatran assoziierte Blutungen ein Antidot (Idarucizumab) zur Verfügung, welches in Studien eine rasche und nahezu vollständige Elimination sowie suffiziente Hämostase aufzeigen konnte. Für Blutungen unter Faktor Xa-Inhibitoren besteht aktuell großer Handlungsbedarf, da bislang kein Antidot verfügbar ist und es ebenso unklar ist, ob in der klinischen Praxis eine relevante Antagonisierung durch gängige Substanzen, z. B. PPSB oder gefrorenes Frischplasma (GFP) erreicht werden kann. In dieser Übersichtsarbeit liegt der Schwerpunkt auf der Akut-Behandlung einer OAK-ICB und versucht anhand der aktuellen Datenlage konkrete Behandlungsoptionen aufzuzeigen. Ferner werden gegenwärtige Studien zur intensivmedizinischen Behandlung der ICB beleuchtet, um daraus relevante Implikationen für die Therapie einer OAK-ICB abzuleiten.
Study on the Intention of Personalized Group Travel

With the rapid development of "single economy" in China, and the continuous expansion of customized tourism market, this study explores the impact of personalized services, group services, tourism safety, and tourists' word-of-mouth on consumers' personalized group tourism willingness from the perspective of personalized group tourism. In this study, 447 questionnaires were collected, 40 invalid questionnaires and 407 effective samples were deducted, and the effective sample rate was 91%. The results show that personalized service, tourists' word-of-mouth, group service and tourism safety have significant positive effects on the personalized group intention; especially, personalized service has the greatest impact on the personalized group intention, while tourism safety has only a slight significant impact on the personalized group intention. Keywords—personalized service; groups service; tourist wordof-mouth; travel safe; personalized group intention
Understanding How IT Capability Impacts Sustainable Competitive Advantage through Business Process Management

Business Process Management or BPM is the blueprint of how work is performed in any organisation to deliver customer requirements. Sustainable Competitive Advantage or SCA pushes organisations to adopt flexibility and dynamism into their systems, processes and culture. A study was carried out to determine the influence of BPM on SCA, and to identify the antecedents of BPM in creating SCA. One of the antecedents’ of the study was IT capability. The study was based on organisations in Malaysia. The results from the study revealed that IT capability failed to observe significant relationship to BPM and SCA. In an attempt to understand further this phenomenon, a series of interviews were carried out on 3 companies representing the telecommunications, consulting and manufacturing industries. The findings revealed that while IT capability is a “must-have”, there are numerous factors that may influence or hinder the effectiveness of IT capability implementation.
The Effect of Argumentation-Based Social Studies Teaching on Academic Achievement, Attitude and Critical Thinking Tendencies of Students

Argumentation-based learning is important for individuals to gain a place in social life, to adapt themselves to social life, to solve the problems they encounter and to use critical and scientific approaches. At this point, it is considered that students should be supported to solve problems efficiently, to establish a cause-effect relationship and to research the scientific background of a problem by implementing argumentation-based learning in social studies course. Therefore, the aim of this research was determined as to reveal the effect of argumentation-based learning in the fourth-grade social studies course on the academic achievement, attitude and critical thinking tendencies of students. The study group of the research consisted of 51 fourth-grade students. This research included the embedded design from the mixed method designs. In the research, subject area achievement test, attitude towards the social studies course scale and UF/EMI Critical Thinking Tendency Scale and six activities that were developed in accordance with the argumentation-based learning approach were used as data collection tools. As a result of the research, it was determined that in social studies course with implementation of argumentation-based learning, the levels and qualities of the arguments that were developed by the students showed an increase throughout the research. Furthermore, it was concluded that with argumentation-based learning in social studies courses, positive developments were observed for academic achievement, attitude towards the social studies course and critical thinking tendencies of students.
Successors of locally compact topological group topologies on abelian groups

For a group G, let G(G) be the lattice of all topological group topologies on G. We prove that if G is abelian, τ, σ ∈ G(G) and σ is a successor of τ in G(G), then σ is precompact iff τ is precompact. This fact is used to show that if a divisible or connected topological abelian group (G, τ) contains a discrete subgroup N such that G/N is compact, then τ does not have successors in G(G). In particular, no compact Hausdorff topological group topology on a divisible abelian group G has successors in G(G) and the usual interval topology on R has no successors in G(R). We also prove that a compact Hausdorff topological group topology τ on an abelian group G has a successor in G(G) if and only if there exists a prime number p such that G/pG is infinite. Therefore, the usual compact topological group topology of the group Zp of p-adic integers does not have successors in G(Zp). Our results solve two problems posed by different authors in the years 2006–2018.
Humanization of SRGAP2C expression increases cortico-cortical connectivity and reliability of sensory-evoked responses in the mouse brain

The remarkable cognitive abilities characterizing humans has been linked to unique patterns of connectivity characterizing the neocortex. Comparative studies have shown that human cortical pyramidal neurons (PN) receive a significant increase of synaptic inputs when compared to other mammals, including non-human primates and rodents1–4, but how this may relate to changes in cortical connectivity and function remains largely unknown. We previously identified a human-specific gene duplication (HSGD), SRGAP2C, that, when induced in mouse cortical PNs drives human-specific features of synaptic development, including a correlated increase in excitatory (E) and inhibitory (I) synapse density5, 6. However, the origin and nature of this increased connectivity and its impact on cortical circuit function was unknown. Here, using a combination of transgenic approaches and quantitative monosynaptic tracing, we demonstrate that humanization of SRGAP2C expression in the mouse cortex leads to a specific increase in local and long-range cortico-cortical inputs received by layer 2/3 cortical PNs. Moreover, using in vivo 2-photon imaging in the barrel cortex of awake mice, we show that humanization of SRGAP2C expression increases the reliability and selectivity of sensory-evoked responses in layer 2/3 PNs. Our results suggest that the emergence of SRGAP2C during human evolution led to increased local and long-range cortico-cortical connectivity and improved reliability of sensory-evoked cortical coding.
DETECTION OF MALICIOUS ACTIVITIES (DOMAIN, CODE, URL, USERS BEHAVIOUR ANALYSIS) BY USING J48

: Malware is malicious software consist of malignant program code which are synchronized by attackers. It has becomes essential task for detecting and analysing malicious activity for domain, code ,URL, User behavior in large scale social network.Research work have discovered around 1million new malware samples per quarter. Hence the paper has proposed the framework to combine “runtime behavior” with “static structures” to detect malware variants.Committing financial fraud and propagating malware and spam are very common criminal actions for people engaged in accessing uniform resource locators (URLs) and online social networks (OSN). OSNs also open the door for harmful activities and behaviors. URLs are malicious which redirects users to phishing (malicious) websites Thus to stop such activity a spam and malicious URLs detection system is required by removing spam content and malicious URLs in Email. This paper proposed methodology for “Detection of malicious activities (domain, code, URL, users behaviour analysis) by using J48”. To solve the problem, this paper proposed the integrated machine learning methods and framework consisting of J48 in detecting the malware accurately .
PTU-054 Out of hours colonoscopy-are we compromising on quality?

Introduction Endoscopy units nationwide are now offering out of hours (OOH) endoscopy as a means of dealing with ever increasing service demands. It is known that quality of colonoscopy can vary with timing throughout the day and there is a paucity of data regarding quality of OOH procedures1,2. Our aim was to investigate the quality of colonoscopies carried out during evening and Saturday lists at Sheffield teaching hospitals (STH) since the introduction of OOH services. Method We retrospectively collected and analysed demographical and procedure related data for non-bowel cancer screening colonoscopies performed between November 2015 to October 2016. Procedures were grouped according to the day of the week and timing of session (am, pm and evening). Kleanprep was used as bowel preparation in the vast majority of procedures. Bowel preparation was recorded at the time of endoscopy according to the Aronchick scale and classified as adequate (excellent/good) or inadequate (fair/poor) for the purpose of statistical analysis. Results Out of the 5150 colonoscopies that were carried out 2487 were male and 2663 were females. Table 1 summarises the differences between routine and OOH colonoscopy. It is our unit’s policy not to book patients older than 65 years of age on evening and Saturday lists and this resulted in a significantly lower mean age. Quality of bowel preparation was significantly lower in morning sessions, including Saturdays compared to afternoon and evenings however this did not translate into any significant difference between polyp detection rates (PDR). Caecal intubation rate (CIR) was slightly higher on Saturdays however this did not reach statistical significance. Weekday p-value Saturday p-value am pm evening am Mean age±95% CI (years) 58.6±0.67 59.0±0.67 55.6±1.60 0.001 (Anova) 56.3±1.3 0.005 (Anova) PDR 555/2141 (25.9%) 590/2255 (26.2%) 85/340 (25.0%) 0.899 (χ2) 108/414 (26.1%) 0.983 (χ2) CIR 1998/2141 (93.3%) 2103/2255 (93.3%) 318/340 (93.5%) 0.982 (χ2) 398/414 (96.1%) 0.079 (χ2) Inadequate bowel preparation 502/2093 (24.0%) 350/2150 (16.3%) 44/319 (13.8%) 0.001 (χ2) 104/414 (25.1%) 0.001 (χ2) Conclusion From our experience quality of OOH colonoscopy including Saturdays is comparable to that of routine lists and is an effective means of reducing waiting list pressures. A possible explanation for the better bowel preparation seen in afternoon and evening lists could be the use of split dosing which hasn’t been introduced yet for morning procedures in our centre. References . Teng TY, Khor SN, Kailasam M, Cheah WK, Lau CC. Morning colonoscopies are associated with improved adenoma detection rates. Surg Endosc. 2016May;30(5):1796–803. Subramanian S, Psarelli EE, Collins P, Haslam N, O’Toole P, Lombard M, Sarkar S. Colonoscopy performance is stable during the course of an extended three-session working day. Endosc Int Open. 2015 Oct;3(5):E494–500. Disclosure of Interest None Declared
Coordinated Interaction: A model and test for globally signed epistasis in complex traits

Interactions between genetic variants – epistasis – is pervasive in model systems and can profoundly impact evolutionary adaption, population disease dynamics, genetic mapping, and precision medicine efforts. In this work we develop a model for structured polygenic epistasis, called Coordinated Interaction (CI), and prove that several recent theories of genetic architecture fall under the formal umbrella of CI. Unlike standard polygenic epistasis models that assume interaction and main effects are independent, in the CI model, sets of SNPs broadly interact positively or negatively, on balance skewing the penetrance of main genetic effects. To test for the existence of CI we propose the even-odd (EO) test and prove it is calibrated in a range of realistic biological models. Applying the EO test in the UK Biobank, we find evidence of CI in 14 of 26 traits spanning disease, anthropometric, and blood categories. Finally, we extend the EO test to tissue-specific enrichment and identify several plausible tissue-trait pairs. Overall, CI is a new dimension of genetic architecture that can capture structured, systemic interactions in complex human traits.
GROWTH ACCOUNTING IN ECONOMIC HISTORY: FINDINGS, LESSONS AND NEW DIRECTIONS

There is now a large volume of growth accounting estimates covering the long run experience of advanced countries. However, most of the studies in economic history are not based on state-of-the-art methods. There is a trade-off between maintaining international comparability and achieving the best results for individual countries. A one-size-fits-all approach will not always do justice to the variety of historical experiences since the conventional assumptions may sometimes be inappropriate. Nevertheless, growth-accounting studies have produced some eye-catching results which provide food for thought both for economic historians and for growth economists. These include (1) the finding that TFP growth was comparatively slow during the First Industrial Revolution, (2) Solow’s famous conclusion that TFP growth accounted for 7/8ths of American labour-productivity growth was atypical, (3) the impact of new general-purpose technologies on growth typically takes a long time to materialize, ICT being the notable exception, and (4) that capital-deepening was much more important relative to TFP growth in east Asian than in western European catch-up growth. Growth accounting is undoubtedly a valuable item in the cliometrician’s toolkit. Nonetheless, we anticipate the introduction of more sophisticated methods and look forward to progress in understanding what explains marked differences in TFP performance.
Evaluation of oxidative stress with thiol disulfide balance parameters in unipolar depression patients with and without mixed symptoms

Objective: Number of studies evaluating oxidative stress in unipolar depression are increasing. The aim of this study was to evaluate the scores of oxidative stress in unipolar depression patients and in mixed type of unipolar depression and to compare these scores with healthy subjects in terms of dynamic thiol/disulfide balance para-meters. Methods: Ninety-eight patients aged between 18 and 65 years with the diagnosis of unipolar depressive disorder diagnosed according to DSM-5 criteria and 97 age- and sex-matched 97 healthy individuals who applied to the Psychiatry Outpatient Clinic of Canakkale Onsekiz Mart University Faculty of Medicine Psychiatry Department between April 2018 and September 2018 were included in the study. Hamilton Depression Rating Scale (HAM-Dand Modified Hypomania Checklist (M-HCL) were used respectively to determine depressive symptoms, manic symptoms and the severity of the disease. Oxidative stress parameters were measured by evaluating fasting blood samples taken from all participants. Results: In the unipolar depression group, the levels of disulfide, total thiol, oxidation-reduction and oxidized thiol levels were found to be statistically significant in favor of oxidation (p
UTILIZING SPECTRAL TRANSCRANIAL DOPPLER TO CHARACTERIZE CEREBRAL HEMODYNAMICS IN A NON-HUMAN PRIMATE (RHESUS MACAQUE)

Abstract : Background: Hemodynamic resuscitation methods are employed to attenuate tissue hypoxia and maintain circulatory homeostasis during hemorrhagic shock. There is increasing advocacy for permissive hypotension resuscitative methods to prevent exsanguination. While data supports this strategy to decrease hemorrhage, questions remain regarding its physiologic effect on the brain. Transcranial Doppler (TCD) ultrasonography is a non-invasive modality that can be used to monitor cerebral perfusion during resuscitation. Utilizing a non-human primate (NHP) model, our goal was to use TCD ultrasonography to characterize normal cerebral hemodynamics, allowing for future comparative analyses of cerebral hemodynamics in animal models of polytraumatic hemorrhagic shock. Materials and Methods: Concurrent with an ongoing NHP protocol, the ophthalmic artery (OA) was insonated to establish baseline TCD values. A transorbital acoustic window was used, imaging was obtained with a 2.0 MHz transducer probe. OA was chosen as the transtemporal window for middle cerebral artery (MCA) resulted in suboptimal waveforms. Results: The following TCD results represent the mean standard deviation, n = 10. Pulsatility index (1.66+-0.33), mean flow velocity (MFV) (21.64+-5.48 cm/s), peak systolic velocity (45.46+-5.48 cm/s), end diastolic velocity (9.84+-3.91 cm/s) and resistance index (0.79+-0.08). Conclusions: We discovered that Rhesus macaques are absent of an adequate transtemporal acoustic window for MCA insonation, and normal resting OA MFV pressure in NHPs mimics reported OA MFV in humans. This data is foundational for our future studies to evaluate cerebral hemodynamics during hemorrhage and the degrees of severity in hemorrhagic shock. Our future goals include the utilization of TCD technology to elucidate a safety threshold for permissive hypotensive resuscitation or aggressive fluid resuscitation as it pertains to cerebral blood flow.