Miracle-dz/UniFAR-FTUs huggingface dataset:
Sondagens versus censos. Uma primeira discussão do conhecimento matemático para ensinar organização e tratamento de dados

Aos professores � actuais ou futuros � cumpre um saber/conhecer mais do que apenas o conteudo na optica do utilizador (saber se algo esta correcto ou nao), encarado como um saber fazer. Devem possuir tambem um conhecimento especifico da profissao que exercem, conhecimento esse que se relaciona com o saber ensinar a fazer. Neste texto abordamos e analisamos uma conceptualizacao sobre o tipo de conhecimento de que, enquanto professores de matematica, necessitamos para ensinar (Conhecimento Matematico para o Ensino), contextualizando-a ao dominio de Organizacao e tratamento de dados, debatendo, em concreto quais as implicacoes, na posterior exploracao das tarefas, entre efectuar um censo e uma sondagem (estudar uma amostra significativa da populacao em estudo). Terminamos com algumas implicacoes e potencialidades deste tipo de abordagem para o ensino/formacao de professores, discutindo, tambem, enquanto formadores de professores, as exigencias que essas potencialidades nos acarretam.
Evaluation of Entrepreneurship Education on Development Program of Product Sorghum

This study aims to evaluate and expand the educational entrepreneurship program based on sorghum products. Education entrepreneurship is a compulsory subject for students Agroindustrial Technology Department. Sorghum is one of the potential industrial materials as raw material of entrepreneurship activities. Data were taken through observation, questionnaire, and interview on sixth semester students. Observations focused on responses from practice, responses to commission business opportunities, and observed the output of beginner entrepreneurs practiced. Data were analyzed statistically, to improve the entrepreneurship education process and to develop the sorghum business in Indonesia. In the education process is accompanied by Center for Sorghum Entrepreneurship (CSE). The results achieved create new educated sorghum-based entrepreneurs, produce healthy entrepreneurship products, and mentoring processes by CSE should be implemented continuously in the development of entrepreneurship education programs and to develop a business of sorghum-based products, so can achieve its goal that is to support the food security and sovereignty program of the Government of Indonesia.
Cone photoreceptor packing density and the outer nuclear layer thickness in healthy subjects.

PURPOSE We evaluated the relationship between cone photoreceptor packing density and outer nuclear layer (ONL) thickness within the central 15 degrees. METHODS Individual differences for healthy subjects in cone packing density and ONL thickness were examined in 8 younger and 8 older subjects, mean age 27.2 versus 56.2 years. Cone packing density was obtained using an adaptive optics scanning laser ophthalmoscope (AOSLO). The ONL thickness measurements included the ONL and the Henle fiber layer (ONL + HFL), and were obtained using spectral domain optical coherence tomography (SDOCT) and custom segmentation software. RESULTS There were sizeable individual differences in cone packing density and ONL + HFL thickness. Older subjects had on average lower cone packing densities, but thicker ONL + HFL measurements. Cone packing density and ONL + HFL thickness decreased with increasing retinal eccentricity. The ratio of the cone packing density-to-ONL2 was larger for the younger subjects group, and decreased with retinal eccentricity. CONCLUSIONS The individual differences in cone packing density and ONL + HFL thickness are consistent with aging changes, indicating that normative aging data are necessary for fine comparisons in the early stages of disease or response to treatment. Our finding of ONL + HFL thickness increasing with aging is inconsistent with the hypothesis that ONL measurements with SDOCT depend only on the number of functioning cones, since in our older group cones were fewer, but thickness was greater.
Simple adaptive partial feedback method for full multiple-input multiple-output channel estimation

Partial feedback in multiple-input multiple-output communication systems provides tremendous capacity gain and enables the transmitter to exploit channel condition and to eliminate channel interference. In the case of severely limited feedback, constructing a quantised partial feedback is an important issue. To reduce the computational complexity of the feedback system, this study introduces an adaptive partial method in which at the transmitter, a set of easy to implement least-square adaptive algorithms is engaged to compute the channel state information. In the proposed method, at the receiver, the time-varying step-sizes of the algorithms are computed and replied to the transmitter via a reliable feedback channel. The transmitter iteratively employs this feedback information to estimate the channel weights. This method is independent of the employed space–time coding schemes and gives all channel components. Complementary solution is given to reduce the computational complexity and simulation examples are given to evaluate the performance of the proposed method.
Toxic Methemoglobinemia Treated With Ascorbic Acid: Case Report

Methemoglobinemia is a disorder characterized by the presence of a higher than normal level of methemoglobin. Prilocaine which is one of the oxidizing local anaesthetics is widely used in many local procedures. The first choice of treatment of complications due to the use of these local anaesthetics is methylene blue, while ascorbic acid is the alternative choice. The side effects of metilen blue restrict its usage in some special conditions. Ascorbic acid is a good alternative drug with limited experience in methemoglobinemia. We present a case of a methemoglobinemia treated with ascorbic acid successfully to emphasize the use of ascorbic acid as an alternative method.
Tamper resistance evaluation of PUF implementation against machine learning attack

Recently, the semiconductor counterfeiting has become a serious problem. To counter this problem, Physical Unclonable Function (PUF) has been attracted attention. However, the risk of machine learning attacks for PUF is pointed out. To verify the safety of PUF, the evaluation (tamper resistance) against machine learning attacks in the difference of PUF implementations is very important. However, the tamper resistance evaluation in the difference of PUF implementation has barely been reported. Therefore, this study evaluates the tamper resistance of PUF in the difference of field programmable gate array (FPGA) implementations against machine learning attacks. Experiments using an FPGA clarified the arbiter PUF of the lookup table implementation has the tamper resistance against machine learning attacks.
Sustainable Supply Chain Management: Analyzing the Past to Determine a Research Agenda

The incorporation of sustainable aspects in the supply chain management (SCM) has become an important topic for researchers and professionals; however, it is a field that yet lacks a systemic understanding. The objective of this article is to conduct an analysis on the international literature about the SCM sustainability topic, by employing a systematic review protocol, covering the period from 2011 to 2016. The content analysis technique was performed, following the procedures of categorical thematic analysis proposed by Bardin (1977), which considers the creation of categories a posteriori, based in the direction senses related to the content analyzed. Besides to present the main characteristics of the articles related to distribution of publications per year, most studied sectors, main methods and approaches used main countries and journals of publications, we categorize the results at the systemic approach level of the sustainable development dimensions. We found that some dimensions are prominent when compared with the others: For example: the environmental one, on the other hand, the social one is approached few times in the papers considered in our analysis. These results also indicate that this type of discussion needs to be extended to other sectors that have not yet been explored. The contribution of this paper lies on the synthetization of the state-of-the-art related to sustainable SCM in the period considered, highlighting the environmental, social and economic dimensions, in order to identify a research agenda. By identifying possible research gaps, the results of this research contribute to guide future investigations on sustainable SCM, aiding researchers and practitioners in this field.
A Hybrid Segmentation Approach Based on Fuzzy Connectedness and Voronoi Diagram

This paper presents a hybrid segmentation approach for medical images that requires minimal manual initialization by integrating the fuzzy connectedness and Voronoi diagram classification algorithms. We start with a fuzzy connectedness filter to generate a sample of tissue from a region to be segmented and obtain image statistics that constitute the homogeneity operator to be used in the next stage. The output of the fuzzy connectedness filter is used as a prior to the Voronoi diagram classification filter. This filter performs iterative subdivision and classification of the segmented image resulting in an estimation of the boundary. The output of this filter is a binary image that can be used to display the 2D or 3D result of the segmentation. Comparing with other medical images segmentation approaches, this hybrid approach integrates boundary-based and region-based segmentation methods that amplify the strength but reduce the weakness of both techniques. The collaboration between two different methodologies tends to result in robustness and higher segmentation quality. We have already realized this approach in our medical images application and got a satisfying result.
An exhaustive study of the epoxy application in TM mode dielectric resonator filters

This paper presents a modified way of epoxy application in the TM mode dielectric resonator based filter fabrication. It has been found that quarter cut dielectric resonators in transversal configuration inside a hollow waveguide cavity are quite sensitive to the application of epoxy used for its placement. An exhaustive study has been performed for the judicious application of the epoxy between various joints of a resonator. An improvement of 15% in the realized Q is obtained without compromising the lap and die shear strength of the resonators joints. The simulation results have been validated through the measurements
Hypoxia Regulates β-Enolase and Pyruvate Kinase-M Promoters by Modulating Sp1/Sp3 Binding to a Conserved GC Element*

The transcription rates of glycolytic enzyme genes are coordinately induced when cells are exposed to low oxygen tension. This effect has been described in many cell types and is not restricted to species or phyla. In mammalian cells, there are 11 distinct glycolytic enzymes, at least 9 of which are induced by hypoxia. Recent reports described a role for the hypoxia-inducible factor-1 (HIF-1) in the transcriptional activation of lactate dehydrogenase A, aldolase-A, phosphoglycerate kinase, and enolase-1 genes. It is not known whether the HIF-1 factor acts exclusively to regulate these genes during hypoxia, or how the other genes of the pathway are regulated. In this paper, we describe analyses of the muscle-specific pyruvate kinase-M and β-enolase promoters that implicate additional mechanisms for the regulation of glycolytic enzyme gene transcription by hypoxia. Transient transcription of a reporter gene directed by either promoter was activated when transfected muscle cells were exposed to hypoxia. Neither of these promoters contain HIF-1 binding sites. Instead, the hypoxia response was localized to a conserved GC-rich element positioned immediately upstream of a GATAA site in the proximal promoter regions of both genes. The GC element was essential for both basal and hypoxia-induced expression and bound the transcription factors Sp1 and Sp3. Hypoxia caused the progressive depletion of Sp3 determined by DNA binding studies and Western analyses, whereas Sp1 protein levels remained unchanged. Overexpression of Sp3 repressed expression of β-enolase promoters. It is concluded that hypoxia activates these glycolytic enzyme gene promoters by down-regulating Sp3, thereby removing the associated transcriptional repression.
MMEDD: Multithreading Model for an Efficient Data Delivery in wireless sensor networks

Nowadays, the use of Wireless Sensor Networks (WSNs) is increasingly growing as they allow a large number of applications. In a large scale sensor network, communication among sensors is achieved by using a multihop communication. However, since the sensor is limited by its resources, sensors' operating systems are developed in order to optimize the management of these resources, especially the power consumption. Therefore, the hybrid operating system Contiki uses a low consumption layer called Rime which allows sensors to perform multihop sending with a low energy cost. This is favored by the implementation of lightweight processes called protothreads. These processes have a good efficiency/consumption ratio for monolithic tasks, but the management of several tasks remains a problem. In order to enable multitasking, Contiki provides to users a preemptive multithreading module that allows the management of multiple threads. However, it usually causes greater energy wastage. To improve multithreading in sensor networks, a Multithreading Model for an Efficient Data Delivery (MMEDD) using protothreads is proposed in this paper. Intensive experiments have been conducted on COOJA simulator that is integrated in Contiki. The results show that MMEDD provides better ratio message reception rate/energy consumption than other architectures.
Vain huonoa taloustiedettä vastustetaan

Helsingin yliopiston kansantaloustieteen professori Vesa Kanniainen pohdiskeli Tieteessa tapahtuu -lehden numerossa 8/2008, miksi taloustieteilijoita vihataan. Kanniaisen kysymys on kuitenkin vaarin asetettu: tiedeyhteiso, ”suuri yleiso” tai ”maailmanparantajien yhteiskuntaluokka” eivat keskimaarin vihaa taloustieteilijoita. Sen sijaan valtavirtaisen taloustieteen kehno nykytila herattaa aiheellista kritiikkia.
North Atlantic Ice-Rafting: A Major Change at 75,000 Years Before the Present

During the last interglacial-to-glacial climatic cycle [127,000 to 10,000 years before the present (B.P.)], the fundamental geographic shift in the main axis of ice-rafting deposition occurred at 75,000 years B.P. An earlier meridional depositional maximum along the Greenland-Newfoundland coasts was superseded by a nearly zonal and much stronger axis some 1500 kilometers to the south along 40�N to 50�N. Both depositional patterns are best explained by cyclonic flow in the subpolor gyre, with the depositional shift related to the retreat of warm, ice-melting North Atlantic drift water from the northwestern half of the gyre. Similar shifts must have characterized preceding interglacial-glacial cycles.
Characterization of a Human Cytomegalovirus with Phosphorylation Site Mutations in the Immediate-Early 2 Protein

ABSTRACT A human cytomegalovirus mutant (TNsubIE2P) was constructed with alanine substitutions of four residues (T27, S144, T233, and S234) previously shown to be phosphorylated in the immediate-early 2 (IE2) protein. This mutant grew as well as the wild type at both low and high multiplicities of infection. The mutant activated the major immediate-early, UL4, and UL44 promoters to similar levels, and with similar kinetics, as wild-type virus. However, the TNsubIE2P mutant virus transactivated an endogenous simian virus 40 early promoter 4 h earlier and to higher levels than the wild-type virus in infected human fibroblasts. The modification of the IE2 protein by SUMO-1 (i.e., its sumoylated state) was also examined.
Involvement of leukocyte (β2) integrins (CD18/CD11) in human monocyte tumoricidal activity

Appropriately activated mononuclear phagocytes mediate contact‐dependent tumoricidal activity. Adhesion structures involved in contact‐dependent tumor cytotoxicity have not been defined. The present study was aimed at identifying the adhesion structures involved in the tumoricidal activity of activated (IFN‐γ + LPS) human monocytes. Tumor cells of different histological origin were used as targets in a 48‐hr cytolysis assay. Anti‐CD18 (integrin β2 chain) monoclonal antibodies (MAbs) substantially (50–40%) inhibited human monocyte cytotoxicity. When the role of different a‐chains was studied, anti‐αL (CD11a, LFA1), anti‐αM (CD11b, Mac‐1) and anti‐αX (CD11c, p150.95) caused marginal inhibition, but the effect of the 3 combined was comparable to that of anti‐CD18. Anti‐CD 18 MAb did not affect the release of various cytotoxic molecules (e.g. TNF) by activated human monocytes. Activated monocytes showed augmented binding to target cells and anti‐CD18 MAb inhibited the binding of resting and activated monocytes to tumor target cells. While IFN‐γ alone augmented expression of leukocyte integrins and LPS had no effect, the 2 activation signals, combined for optimal stimulation of tumoricidal activity, resulted in no appreciable increase in these leukocyte adhesion molecules, as assessed by flow cytometry. Our results suggest that the augmented CD 18‐dependent binding of activated monocytes on tumor cells depends mainly upon changes in the adhesive properties of these molecules rather than upon increased numbers on the cell surface. Anti‐1CAM‐1 MAb significantly reduced monocyte cytotoxicity on tumor cells, which is consistent with a role of the CD11/CD18 adhesion pathway. These results implicate “activated”︁ leukocyte (β2) integrins (CD11 /CD18) as important adhesion molecules in the contact‐dependent tumoricidal activity of human monocytes.
MUMBLE: A Flexible System for Language Production

MUMBLE Is a general purpose subsystem Intended as the final output segment of the natural language interface of an expert system. As described in [1], it takes plans expressed in nearly any conceptual representation and realizes them as English texts, integrating the different parts of the plan linguistically as well as taking full responsibility for the grammatically of the output and its coherency as a discourse. MUMBLE has been under development since 1975, having undergone four major overhauls, and is being used at MIT, BBN, and UMass. It is available from the author in a common dialect of maclisp and lispmachine lisp, with a translation to franz lisp underway and one to interllsp in planning. The kernal of MUMBLE consists of roughly 400 functions in eleven files, and as interpreted code occupies roughly 150k words of memory on a PDP/10. Runtimes are a function of the complexity of the input plans, but fall around . 6 to 2 seconds per word of output text (again running Interpreted). Input plans for MUMBLE are invariably composed from the same data structures that the expert program uses Itself to represent what it wants to talk about. They are interpreted for production by a "dictionary" that one writes for each new expert program. This dictionary associates expressions from the expert with English phrases (or phrase schemas if the expression takes arguments); should more than one phrase be possible, one either includes a set of discriminating tests or makes use of the system supplied routine for managing synonyms. Example dictionaries are available for five different domains and their internal representations. MUMBLE supplies an extensive vocabulary of linguistic relations and operations in terms of which to write the needed English phrases, and at runtime maintains a thoroughly annotated abstract description of the linguistic structure already built from those elements of the plan that have been realized so far. This structure will automatically constrain the realization of the rest of the elements to insure their grammatlcality with respect to what has gone before; it also provides a context-sensitive reference for any heuristics one may write (or adapt from McDonald and Information Science Massachusetts those already included) to govern decisions such as the proper length of sentences, how to express contrasts, or how elaborate a description to use for some object. The paragraph below is an example of MUMBLE'S output, starting from the given list of assertions. (The task …
Photonic Flash Soldering of Thin Chips and SMD Components on Foils for Flexible Electronics

Ultrathin bare die chips and small-size surface mount device components were successfully soldered using a novel roll-to-roll compatible soldering technology. A high-power xenon light flash was used to successfully solder the components to copper tracks on polyimide (PI) and polyethylene terephthalate (PET) flex foils by using a lead-free solder paste. Results are compared with oven-reflowed solder joints on PI substrates. The delicate PET foil substrates were not damaged owing to the selectivity of light absorption, leading to a limited temperature increase in the PET foil while the chip and copper tracks were heated to a temperature high enough to initiate soldering. The microstructure of the soldered joints was investigated and found to be dependent on the photonic flash intensity. Reliability of the photonically soldered joints during damp heat testing and dynamic flexing testing was comparable with the reflowed benchmark and showed increased reliability compared with anisotropic conductive adhesives bonded on PET foils.
The Effectiveness of Anti-Crisis Labor Market Measures in the European Union

With the purpose of minimizing the consequences of the economic recession on the labor market, and particularly on workers, EU member states adopted specific anti-crisis labor market measures or adjusted the existing policies. In this respect, this paper aims at analyzing the relation between different labor market policy combinations issued by member states and their social model and employment protection legislation, also considered as a combination of flexibility and security tools, and tries to identify which system and policies seem to provide a higher level of effectiveness in tackling the crisis.
Brain Connectivity Structure in Spinal Cord Injured: Evaluation by Graph Analysis

The problem of the evaluation of brain connectivity has become a fundamental one in the neurosciences during the latest years, as a way to understand the organization and the interaction of several cortical areas during the execution of cognitive or motor tasks. Following an approach that derives from the graph theory, we analyzed the architectural properties of the networks obtained by the use of DTF measures on the cortical signals estimated from the high resolution EEG recordings. The present work aims at analyse the structure of cortical connectivity during the imagination of a limb movement in spinal cord injured patients, by the computation of the characteristic path length L and the cluster indices Cin and Cout
Pneumocystis pneumonia following rituximab.

journal.publications. chestnet.org Figure 1. NHANES predicted FEV 1 /FVC and lower 95% CI limit for white men. Gray regions are subjects misclassifi ed by GOLD criteria. Just past 40 years old (vertical dotted line), as age increases, the greater the risk of overdiagnosing COPD. Under 40 years of age, GOLD calls subjects normal that are below the lower 95% confi dence limit of normal. ci 5 confi dence interval; GOLD 5 Global Initiative for Chronic Obstructive Lung Dis ease; NHANES 5 National Health and Nutrition Examination Survey.