Miracle-dz/UniFAR-FTUs huggingface dataset:
THE INFLUENCE OF INBOUND MUSLIM TRAVELLERS’ ATTITUDE ON TRAVEL SATISFACTION TOWARDS REVISIT INTENTION TO MALAYSIA

Muslim travellers segment is gaining attention among the destination marketers as a target market. Thus, ensuring their repeat visitation is among the top priorities of the marketers. However, the factors that make them return to a particular destination are still unclear as studies on Muslim travellers segment are still limited. Nevertheless, previous studies have shown that the availability of Islamic attributes of destination as well as certain destination attributes exert significant influence on travel satisfaction and destination loyalty. Although few studies have shown that availability of Islamic attributes of destination and destination attributes lead to tourist satisfaction as well as inspire multiple return visits, more studies are needed to strengthen the finding. Therefore, this article proposed a study on the influence of Muslim travellers’ attitude towards Islamic attribute of destination and attitude towards destination attributes on their travel satisfaction and repeat visit to Malaysia. The discussion started with the overview of inbound Muslim travellers followed by the importance of revisit to the tourism industry with highlight given to the Islamic attributes of destination, destination attributes and travel satisfaction as the main antecedents of the Muslim travellers’ revisit intention. The future finding of the proposed study will provide valuable information for Malaysian tourism marketing and planning organisations. Thus, effective marketing strategies can be developed to encourage repeat visit from Muslim travellers segment.
The Role of Internal Control in Managing The Risks Specific to The Financial Field

Abstract This article deals with a currently discussed topic, namely that of preventive financial control, a concept that has to ensure a reasonable use of public funds in a transparent, economical, efficient and effective manner. In this sense the issues related to public internal financial control are considered instruments that actively influence the organizational and managerial culture of the public entity in a positive manner by engaging in control actions that are meant to identify and stop the possible illegal activities or actions, fraudulent or uneconomical use of public funds. I further detail the concept of public financial control with the two principal branches, that is the preventive financial control and the preventive financial control proper. The preventive financial control proper, by exercising the control visa for every financial supporting document affecting public funds, is a cornerstone regarding the exercise of financial control activity.
The spectroscopist's lament.

See related article, p 2962. I can’t change the laws of physics! ” Inflected with the appropriate Scottish brogue, this quote brings to mind a character from a well-known classic science fiction television series. However, Scotty’s lament might be that of the clinical MR spectroscopist as well, for there are few areas in medical diagnostic imaging in which the immutable laws of physics pose such direct constraints. In selecting an in vivo spectroscopy protocol, spectral quality (as measured by signal to-noise ratio), spatial resolution, spatial coverage, examination time, and the minimum time to obtain a spectroscopic imaging series are inextricably entwined. Optimization of one parameter necessitates a compromise elsewhere. For instance, improvement of the spatial resolution of a MR spectroscopic imaging (MRSI) series can be achieved, but at the expense of a longer acquisition time and/or reduced signal to-noise resolution of the spectra. The laws of physics will not have it otherwise. Although the first in vivo 1H spectrum from the brain of a patient poststroke was reported almost 25 years ago,1 followed a few years later by 1H spectroscopic imaging in one2 and 23 dimensions, the difficulty of obtaining good quality MRSI from patients after stroke, especially in the acute phase, has been one of the factors limiting the more widespread application of MRSI to stroke. Elderly, sick, often confused patients …
Toxicity testing: the search for an in vitro alternative to animal testing

Abstract Prior to introduction to the clinic, pharmaceuticals must undergo rigorous toxicity testing to ensure their safety. Traditionally, this has been achieved using in vivo animal models. However, besides ethical reasons, there is a continual drive to reduce the number of animals used for this purpose due to concerns such as the lack of concordance seen between animal models and toxic effects in humans. Adequate testing to ensure any toxic metabolites are detected can be further complicated if the agent is administered in a prodrug form, requiring a source of cytochrome P450 enzymes for metabolism. A number of sources of metabolic enzymes have been utilised in in vitro models, including cell lines, primary human tissue and liver extracts such as S9. This review examines current and new in vitro models for toxicity testing, including a new model developed within the authors’ laboratory utilising HepG2 liver spheroids within a co-culture system to examine the effects of chemotherapeutic agents on other cell types.
Comparison of Responsiveness Level in Iranian Public and Private Physiotherapy Clinics: a Cross-Sectional Multi-center Study

Introduction: Responsiveness is a main goal of health systems. Responsiveness focus on the non-medical aspects of health services delivery. This study was aimed to assess responsiveness level in public and private physiography clinics. Methods: In this multicenter cross sectional study, 403 patients refers to 16 public and 64 private physical therapy clinics were studied randomly in Ahvaz, Iran, from 2013 to 2014. Data were collected based on a valid health system responsiveness questionnaire that was developed by WHO. Health system responsiveness questionnaire for outpatients care includes seven components and 25 questions. Statistical relationship between responsiveness level of centers and patients characteristics was analyzed using Pearson coefficient, Independent t-test and one-way ANOVA. Results: Out of 403 patients, 299 (74.19%) patients were women. The mean (±SD) age of the patients was 42(±14.18) years and 92.1% of patients were 65> years. Responsiveness status in private and public physiotherapy clinics was assessed excellent (26.93±5.2) and very well (21.08±5.8) respectively. In private clinics, the mean score of communication dimension (3.96±1) and autonomy dimension (3.95±0.9) was higher than other dimensions. In public clinics the mean score of dignity (3.30±0.8), autonomy (3.16±0.9), and prompt attention (3.12±1) was higher than other areas respectively. In public and private clinics, quality of basic amenities area had the lowest score. Conclusions: The results showed that the some patients and center characteristics such as gender and work shift were factors affecting assessment of responsiveness. Responsiveness level in private centers was better than publics.
Analytical-Algebraic Approach to Solving Chaotic System

The aim of this paper is to present the application of the analytical series technique to study properties of the nonlinear chaotic dynamical systems. More specifically, Laplace–Adomian decomposition method is applied to Rossler system and the so-called generalized Lorenz system. Some advantages and possible applications of this approach are discussed. Results are illustrated by numerical computations.
DNA Mismatch Repair Abnormalities in Acinar Cell Carcinoma of the Pancreas: Frequency and Clinical Significance

Objectives Acinar cell carcinoma (ACC), including its mixed variants, is a rare pancreatic malignancy. Recent reports have documented its occurrence in Lynch syndrome. Our aim was to evaluate the frequency and clinicopathologic significance of DNA mismatch repair (MMR) deficiency in ACCs in general. Methods Mismatch repair protein expression was evaluated by immunohistochemistry in a series of 36 ACC cases that were treated at our institution and had sufficient clinical information and pathologic material. Results Loss of MMR protein was observed in 5 ACCs (5/36, 14%): 2 lost MLH1/PMS2, 2 lost MSH2/MSH6, and 1 lost MSH6 alone. The 1 MSH6-deficient case and 1 of the 2 MSH2/MSH6-deficient cases had a known history of Lynch syndrome, carrying a germline mutation in MSH6 and MSH2, respectively. None of the 5 tumors showed distinctive morphology. Two of the 5 patients died of disease 6 and 21 months after diagnosis. In contrast, in the MMR-normal group, only 1 of 30 patients died of disease (median follow-up, 32.5 months). Conclusions Mismatch repair protein deficiency is not uncommon in ACCs, occurring in 14% of the cases in this series. The MMR-deficient ACCs did not show distinctive morphologic features and were clinically no less aggressive than MMR-normal ACCs.
Educando en privacidad en el uso de las redes sociales

Many adolescents use social networks extensively to increase their sociability without being aware of the value of their shared information and the potential risks related to their privacy and security in the network. Misuse or unauthorized disclosure of users’ private information may have unexpected consequences on people’s lives. Therefore, prevention and training in data protection is essential to avoid risks on the Internet. Several authors consider that training in the proper use of social networks should be integrated into the formative curriculum of adolescents and focus not only on theoretical training but also on promoting changes in attitudes and behavior. For this reason, we have developed a restricted access social network application (called Pesedia), which allows children and adolescents to be educated about the risks of social networks and also encourages a change of attitude toward a responsible and adequate use of privacy in social networks. Using Pesedia, an experience has been realized with 134 children between 12 and 14 years, within the framework of Escola d’Estiu 2016 (Summer School) of the Universitat Politecnica de Valencia. Through a set of proposed games, children and adolescents interact in Pesedia and learn to detect risky actions that, if carried out in a public social network could compromise their privacy. With such games, children and adolescents are aware of, among other things, the dangers of public exposure of data, the labeling and geo-positioning of photos, the decontextualization of conversations, as well as the future repercussions of our digital fingerprint. In this articlearticle, we present the characteristics of this social network, the developed workshops, and the main results of this experience.
Biomarkers in the Overactive Bladder Syndrome

Overactive bladder (OAB) is a symptomatic complex affecting both men and women. The overall incidence is above 10% but may exceed 40% in the elderly population (Irwin et al., 2006; Irwin et al., 2009; Sexton et al., 2009a). OAB is defined by the International Continence Society (ICS) as a clinical syndrome characterized by urinary urgency, with or without incontinence, usually with frequency and nocturia (Abrams et al., 2002, 2003; Hashim & Abrams, 2007). Urgency, which is a storage symptom defined as a sudden compelling desire to pass urine difficult to defer, is the hallmark symptom as it is the only one that must be present in order to establish the diagnosis of OAB (Abrams et al., 2002, 2003). Several comorbidities are very common among OAB patients, including depression, insomnia and fractures (Coyne et al., 2008; Sexton et al., 2009a; Sexton et al., 2009b). The economic costs of OAB, associated with medical consultations, therapy and diminished productivity at work, may reach billions of dollars (Irwin et al., 2009) and will certainly increase with the demographic shift of an ageing population.
Combination Strategies for 2D Features to Recognize 3D Gestures

In this study, using a two camera setup, we designed a system that recognizes 3D gestures. When 3D reconstruction is not possible or infeasible, combining 2D hand trajectories at feature or decision level increases the system performance drastically. The trajectories are extracted by tracking the center-of-mass of the hand and the width, height and orientation of the enclosing ellipse. Trajectories are then smoothed using a Kalman filter. Following the translation and scale normalization, the trajectories are modelled using hidden Markov models (HMM) and using support vector machines (SVM) by converting the trajectories to fixed length using re-sampling. Trajectories extracted from different cameras are combined at different levels and the effect to the system performance is observed. The best result is obtained by modelling the trajectories using HMMs and combining at decision level, with %1 error in 210 test examples
Analysis of the costs and revenues of agricultural products in the selected countries of Central Europe

The paper compares and evaluates the development of the total production costs incurred for the production of selected agricultural crops and generated revenues in four Central European countries. Consequently, it also assesses the profit or loss statement. The comparison is made between countries and over time. The paper also assesses the proportion of overhead costs to total costs incurred for own crop production. We also track the profitability of incurred costs for agricultural products in these countries in order to provide information not only to scientists, but also representatives of agricultural industry. The partial objective of the paper is also to assess costs and revenues separately for livestock and crop production. In assessing agricultural companies are still used traditionally calculation methods. Currently, traditional cost calculation methods are not considered sufficiently accurate. The paper points out to the possibilities of modern cost management and their benefits to the traditional agricultural sector.
Integration of Relational and Textual Biomedical Sources

Summary Objectives: Bringing together structured and text-based sources is an exciting challenge for biomedical informaticians, since most relevant biomedical sources belong to one of these categories. In this paper we evaluate the feasibility of integrating relational and text-based biomedical sources using: i) an original logical schema acquisition method for textual databases developed by the authors, and ii) OntoFusion, a system originally designed by the authors for the integration of relational sources. Methods: We conducted an integration experiment involving a test set of seven differently structured sources covering the domain of genetic diseases. We used our logical schema acquisition method to generate schemas for all textual sources. The sources were integrated using the methods and tools provided by OntoFusion. The integration was validated using a test set of 500 queries. Results: A panel of experts answered a questionnaire to evaluate i) the quality of the extracted schemas, ii) the query processing performance of the integrated set of sources, and iii) the relevance of the retrieved results. The results of the survey show that our method extracts coherent and representative logical schemas. Experts’ feedback on the performance of the integrated system and the relevance of the retrieved results was also positive. Regarding the validation of the integration, the system successfully provided correct results for all queries in the test set. Conclusions: The results of the experiment suggest that text-based sources including a logical schema can be regarded as equivalent to structured databases. Using our method, previous research and existing tools designed for the integration of structured databases can be reused – possibly subject to minor modifications – to integrate differently structured sources.
Power-Loss Analysis and Efficiency Maximization of a Silicon-Carbide MOSFET-Based Three-Phase 10-kW Bidirectional EV Charger Using Variable-DC-Bus Control

It is expected that wide-bandgap devices like silicon-carbide MOSFETs and gallium-nitride HEMTs could replace Si devices in power electronics converters to reach higher system efficiency. This paper adopts the conventional half-bridge LLC topology to realize a 10-kW all-SiC bidirectional charger used in electric vehicles. Though it is a well-known topology for the unidirectional charger, it has not been comprehensively explored for the bidirectional energy flow yet. A double-pulse-test (DPT) platform is utilized to provide accurate power losses. A state-space model is built to obtain accurate switching current waveforms, which is eventually combined with the DPT results to accurately predict the system efficiency. Based on this model, to further enhance the system efficiency, the dc-bus voltage is varied with LLC dc/dc converter running at the resonant frequency through the whole power range. Experimental results validated that the proposed approach could realize the bidirectional power flow. By varying the dc-bus voltage, the V2G and G2V modes reach ~96 % wall-to-battery efficiency.
CD4‐POSITIVE HELPER T LYMPHOCYTES MEDIATE MOUSE CARDIAC ALLOGRAFT REJECTION INDEPENDENT OF DONOR ALLOANTIGEN SPECIFIC CYTOTOXIC T LYMPHOCYTES

Mouse heterotopic cardiac allograft recipients were depleted of CD4+ or CD8+ T lymphocytes in vivo to assess cellular requirements for graft infiltration, tissue damage, and acute allograft rejection. Modified limiting dilution analysis was employed to quantitate IL-2-producing Th lymphocytes (HTL) and CTL infiltrating the graft. Results were correlated with graft function and histologic evidence of tissue damage. In unmodified recipients, large numbers of donor alloantigen-specific CTL infiltrated the graft, overshadowing a modest number of HTL. CTL infiltration coincided with tissue damage and loss of graft function, suggesting a key role for CTL in rejection. In vivo treatment with anti-CD4 mAb inhibited both HTL and CTL infiltration, and no histologic evidence of tissue damage was observed. This observation suggested that HTL, although few in number, regulated the development of effector CTL and/or entry of these CTL into the graft. Reconstitution of HTL-depleted recipients with IL-2 resulted in graft infiltration by stimulated CTL, as assessed by modified limiting dilution analysis. However, these stimulated CTL failed to mediate tissue damage, and graft survival was prolonged. Unlike CTL obtained from unmodified recipients, graft-infiltrating CTL of IL-2-reconstituted mice were incapable of directly lysing donor cells in a 51Cr release assay. Hence, while IL-2 facilitated partial CTL differentiation and mobilization to the graft, additional signals appear necessary for maturation into lytic CTL. Furthermore, in recipients depleted of CTL by treatment with anti-CD8 mAb, HTL infiltrating the allograft, though few in number, were associated with extensive tissue damage and loss of graft function. These data suggest a less important role for CTL in the rejection process, and indicate that graft-infiltrating CTL are insufficient as sole mediators of cardiac allograft rejection. Potential mechanisms by which CD4+ HTL mediate cardiac allograft rejection independent of CTL are discussed.
A Compact Dual- and Wideband Cavity-Backed Slot Subarray

A compact design for dual- and wideband slot sub-array is presented in this letter. The cavity-backed subarray is fed by two microstrip lines on the top layer of one substrate for 900 and 1800 MHz bands, respectively. With the use of ridged slots backed by a conductor plate with three rectangular cavities, a compact design is realized for a dual- and wideband subarray with very good isolation and symmetric radiation patterns. A prototype is fabricated and tested in an anechoic chamber. The measured 10-dB return loss bandwidth of the slot subarray is 36% for 900-MHz band and 35% for 1800-MHz band, respectively. The measured gains are 7.0 dBi at 920 MHz and 10.2 dBi at 1800 MHz
Conservation and improvement for the production of meat type quail in Bangladesh

The present study was conducted with the aim to develop a meat type quail genotype for our existing farming system. A total of 1866 quails from four genotypes namely Japanese, White, Black and Brown were used in the study for this purpose. The parent males and females were maintained in cages for single pair mating through close breeding system for producing each generation. Eggs were hatched in a batch for producing third generation (G3). Egg weight were significantly influenced (p<0.05) by genotype. Highest egg weight was found in White (11.60±0.42) genotype followed by Japanese (10.35±0.30), Brown (10.30±0.42) and Black (9.78±0.65) quail genotypes. The highest hatchability of incubated eggs was found in Japanese (71.01%) genotype and lowest in Black (31.03%). White genotype of quail is significantly better for egg weight, chick weight and chick: egg ratio than that of their counterparts. Significantly higher body weight was found in Black (131.90 ± 1.24) genotype followed by White (131.86 ± 0.76), Brown (128.35 ±0.78) and Japanese (112.57 ± 0.53) quail genotype at different periods of age. Egg production was found significantly (p<0.001) differed by genotypes. Black genotype was found highest (97.31±1.05%) while White genotype was found lowest (84.23±0.67%) performer in terms of egg production. It was concluded that the Black quail genotype can be used for meat type quail development in the country for its higher body weight and egg production. Asian Australas. J. Biosci. Biotechnol. 2016, 1 (3), 425-428
Genome-wide scan for interacting loci affecting human cholesteryl ester transfer protein-induced hypercholesterolemia in transgenic human cholesteryl ester transfer protein F2-intercross rats

Objective We documented susceptibility in Dahl S rats to coronary atherosclerosis upon the transgenic expression of human cholesteryl ester transfer protein (hCETP) producing severe combined hyperlipidemia, as detected in Tg[hCETP]53 (Tg53) Dahl S rats. In other genetic backgrounds (i.e. Dahl R, spontaneously hypertensive rat strains) transgene expression does not lead to severe combined hyperlipidemia. This study aimed to identify genetic loci that modify the effect of hCETP on hypercholesterolemia observed in different genetic contexts. Methods To identify quantitative trait loci (QTL) that affect hCETP-mediated hyperlipidemia in Tg53 Dahl S rats in contrast to Tg53 Dahl R rats we performed a genome-wide scan for QTL affecting plasma total cholesterol in an F2[TghCETP (R × S)]-intercross male population (n = 159) that are transgenic for the Tg[hCETP]53 transgene. Hybrids were genotyped with 121 informative polymorphic markers. Results We detected three novel hCETP-dependent QTL for hypercholesterolemia: one on chromosome 3 with suggestive linkage [logarithm of odds score derived from likelihood ratio statistic using a factor of 4.6 (LOD) 2.26]; one on chromosome 9 with significant linkage (LOD 4.15), and one on chromosome 11 with significant linkage (LOD 3.48) that have not been detected in other rat intercrosses. Conclusion Three cholesteryl ester transfer protein (CETP)-interacting loci were identified in a Tg53 Dahl S rat intercross study affecting cholesterol metabolism. These results could partly explain the controversy regarding the atherogenic role of CETP in humans, suggesting the hypothesis that putative CETP interacting genes confound or play an important role in CETP-mediated pro-atherogenic susceptibility in humans. Overall, these observations reiterate the key role of epistasis in complex, multifactorial traits.