Miracle-dz/UniFAR-FTUs huggingface dataset:
The conceptual modeling in the process of computer-assisted generation of data warehouse models

This paper introduces the methodological guidelines for the data warehouse model computer assisted generation. These guidelines are divided into four different stages: information analysis, conceptual model and logical design are the first ones and the last one occurs within them and it is known as the traceability stage. These stages describe a data warehouse design proposal can be obtained from the inherited operational systems (E/R). One of the main stages we considered to be important is the data warehouse conceptual model. This paper goes deeper into the different ways to obtain the conceptual model from the logical structure of the institutional inherited systems, taking into account that these systems generally use a relational model in its structure. In order to accomplish this, it is proposed to use the interrelation among entities to generate a graph of interrelation of attribute and then apply a set of design rules to obtain the conceptual model.
PLAGIARISM AND SECOND LANGUAGE WRITING IN AN ELECTRONIC AGE

It has been observed that plagiarism is a problem across specialities and professions, and it is probably becoming more rampant than ever in this electronic age. Based on a body of literature primarily in applied linguistics, this review focuses on textual plagiarism and antiplagiarism in second language academic writing. Following a conceptualization of plagiarism and an examination of some terminology employed in the literature to address the complexity of the issue, a number of perspectives taken upon plagiarism in the literature are examined. These include a cultural interpretation, a developmental perspective, a disciplinary perspective, student beliefs and practices, faculty perceptions, and a focus upon antiplagiarism pedagogy. The challenge and opportunity involved in dealing with plagiarism is then highlighted by reviewing work that has analyzed the problem in connection with the Internet, by exemplifying some antiplagiarism detection devices, and by relating these to John Sinclair's “idiom principle” of linguistic structure. The article ends by suggesting a few lines of future research on plagiarism.
Bedeutung und Methodik von körperlichem Training bei COPD1

Die pneumologische Rehabilitation ist eine evidenzbasierte multidisziplinäre und umfassende Behandlung für Patienten mit chronischen Erkrankungen der Atmungsorgane, die Symptome aufweisen und in ihren Alltagstätigkeiten eingeschränkt sind [1]. Sie verfolgt das Ziel, durch einen multifaktoriellen Therapieansatz den aktuellen subjektiven und objektiven Status ebenso wie den Verlauf der Erkrankung zu verbessern. Um dieses zu erreichen, kommt ein für jeden Patienten individuell erstelltes Therapieprogramm zur Anwendung, bei dem über einen definierten Zeitraum verschiedene, wissenschaftlich fundierte diagnostische und insbesondere therapeutische Verfahren genutzt werden. Hierfür ist ein multidisziplinäres Rehabilitationsteam erforderlich, dem Ärzte, Psychologen, Pflegepersonal, Sozialpädagogen, Sozialarbeiter, Physiotherapeuten, Sportwissenschaftler, Ergotherapeuten und Ernährungsberater angehçren. Die Therapiebausteine (l" Tab. 1) variieren in Abhängigkeit von den für jeden Patienten individuell formulierten Rehabilitationszielen. Die Effektivität des Gesamtkonzeptes der pneumologischen Rehabilitation bei COPD ist durch zahlreiche randomisierte Studien und Metaanalysen [2, 3] auf hçchstem Evidenzgrad gesichert. Die Effekte der pneumologischen Rehabilitation bei COPD werden in der aktuellen GOLD-Leitlinie [5] hinsichtlich des Evidenzgrades bewertet (l" Tab. 2), was die Bedeutung der pneumologischen Rehabilitation als essenzielle Komponente des Langzeitmanagements unterstreicht. So wird in nationalen [4] wie internationalen Leitlinien [5] die pneumologische Rehabilitation ab dem Schweregrad II nach GOLD, also schon ab einem mittleren Krankheitsstadium und auch in hçherem Lebensalter, empfohlen [6].
Tree extension of micro-pipelines for mixed synchronous-asynchronous implementation of regional image computations

Programmable artificial retinas (PAR) are image sensors with a digital processor in each pixel. PAR based vision systems are our framework. In its basic version, a PAR operates in SIMD mode, which restricts it to low level vision only. To support higher levels of vision, non-SIMD operators have to be settled in each pixel. Programmable connections and asynchronous communications are key ingredients to support regional computations, but under which form? To identify the good ones, we consider adding pixel data simultaneously over different regions as an exemplary primitive. After recalling previous implementations, we propose a novel one based on a tree extension of micro-pipelines that we call convergent micro-pipelines.
Understanding Health Behavior Using Social Network Analysis

: Health of a person plays a vital role in the collective health of his community and hence the well-being of the society as a whole. But, in today’s fast paced technology driven world, health issues are increasingly being associated with human behaviors – their lifestyle. Social networks have tremendous impact on the health behavior of individuals. Many researchers have used social network analysis to understand human behavior that implicates their social and economic environments. It would be interesting to use a similar analysis to understand human behaviors that have health implications. This paper focuses on concepts of those behavioural analyses that have health implications using social networks analysis and provides possible algorithmic approaches. The results of these approaches can be used by the governing authorities for rolling out health plans, benefits and take preventive measures, while the pharmaceutical companies can target specific markets, helping health insurance companies to better model their insurance plans
Is LiFePO4 Technology Ready for Internet of Things

While self-sufficient sensors and actors are about to pave the way for a new computing class, associate Internet of Things applications will highly depend on efficient and reliable storage of electrical energy. Likewise the same is true for electrical based transport systems requiring light weights and high capacities. Recently, novel LiFePO4 based storage cell types with standardized form-factors have become available. These cells tend to be promising in terms of high energy densities, low self-discharge rates and long cycle lives. Anyhow, the aging behavior, maturity, statistical spread and reliability of these new cells have not been analyzed and modeled thoroughly. Therefore, we analyze and compare in this paper the self-discharge behavior, lifetime and reliability of different lithium-based battery cells using a dedicated test bench. We use temperature, voltage, current, and power cycling as acceleration and stress parameters.
The concept of openness behind c and x-MOOCs (Massive Open Online Courses)

The last five years have witnessed a hype about MOOCs (Massive Open Online Courses) presaging a revolution in higher education. Although all MOOCs have in common their scale and free access, they have already bifurcated in two very distinct types of courses when compared in terms of their underpinning theory, format and structure, known as c-MOOCs and x-MOOCs. The concept of openness behind each of the formats is also very different. Previous studies have shown that c-and x-MOOCs share some common features but that they clearly differ on the learning theory and pedagogical model on which they stand. In this paper we extend earlier findings and concentrate on the concept of “openness” behind each format showing important differences.
Changing concepts of cancer stem cells and their application into targeted therapy for cancer

종양조직 내 일부 세포들만이 종양전파 능력이 있다는 암 Cancer stem cells (CSCs) are characterized by self-proliferation, an ability for symmetric/ asymmetric division and an ability to propagate cancer in vivo. Contrary to our expectation, CSCs show a quiescent nature, the morphology of small resting cells, resistance to multiple drugs/radiation, and side-population phenotypes distinct from major cancer cells. Research has been focused on overcoming drug resistance, discovery of biomarkers for CSCs, and tailored treatment targeting CSCs. Recently changing concepts of CSCs reflect the genetic heterogeneity, hierarchy of cancer tissue, and evolving dynamic mutations within one tumor. First, multiple CSC clones with different mutations including initiating driver mutations can coexist within one tumor. Second, CSCs stand at the top of the tumor hierarchy during therapy or disease progression, and the proportions of these clones are changing dynamically, depending on the cancer progression. Third, tailored treatments should be not fixed, according to the initial situation at diagnosis, but appropriate treatment should be attempted in accordance with the dynamic properties of CSCs at each stage of cancer.
Vaccines against anthrax based on recombinant protective antigen: problems and solutions

ABSTRACT Introduction: Anthrax is a dangerous bio-terror agent because Bacillus anthracis spores are highly resilient and can be easily aerosolized and disseminated. There is a threat of deliberate use of anthrax spores aerosol that could lead to serious fatal diseases outbreaks. Existing control measures against inhalation form of the disease are limited. All of this has provided an impetus to the development of new generation vaccines. Areas сovered: This review is devoted to challenges and achievements in the design of vaccines based on the anthrax recombinant protective antigen (rPA). Scientific databases have been searched, focusing on causes of PA instability and solutions to this problem, including new approaches of rPA expression, novel rPA-based vaccines formulations as well as the simultaneous usage of PA with other anthrax antigens. Expert opinion: PA is a central anthrax toxin component, playing a key role in the defense against encapsulated and unencapsulated strains. Subunit rPA-based vaccines have a good safety and protective profile. However, there are problems of PA instability that are greatly enhanced when using aluminum adjuvants. New adjuvant compositions, dry formulations and resistant to proteolysis and deamidation mutant PA forms can help to handle this issue. Devising a modern anthrax vaccine requires huge efforts.
Interneuron Types as Attractors and Controllers.

Cortical interneurons display striking differences in shape, physiology, and other attributes, challenging us to appropriately classify them. We previously suggested that interneuron types should be defined by their role in cortical processing. Here, we revisit the question of how to codify their diversity based upon their division of labor and function as controllers of cortical information flow. We suggest that developmental trajectories provide a guide for appreciating interneuron diversity and argue that subtype identity is generated using a configurational code of transcription factors that produce attractor states in the underlying gene regulatory network. We present our updated three-stage model for interneuron specification: an initial cardinal step, allocating interneurons into a few major classes, followed by definitive refinement, creating subclasses upon settling within the cortex, and lastly, state determination, reflecting the incorporation of interneurons into functional circuit ensembles. We close by discussing findings indicating that major interneuron classes are both evolutionarily ancient and conserved. We propose that the complexity of cortical circuits is generated by phylogenetically old interneuron types, complemented by an evolutionary increase in principal neuron diversity. This suggests that a natural neurobiological definition of interneuron types might be derived from a match between their developmental origin and computational function. Expected final online publication date for the Annual Review of Neuroscience Volume 43 is July 8, 2020. Please see http://www.annualreviews. org/page/journal/pubdates for revised estimates.
Acceptance-focused processes and self-compassion protect pregnant women from developing postpartum depressive and anxiety symptoms and improve relationships with health caregivers

Commentary on: Monteiro F, Fonseca A, Pereira M, et al . What protects at-risk postpartum women from developing depressive and anxiety symptoms? The role of acceptance-focused processes and self-compassion. J Affect Disord 2019;246:522–9. doi: 10.1016/j.jad. 2018.12. 124. Women in the postpartum stage are susceptible to increased risk for mood disturbances.1 …
Antimetastatic Properties of Tea Polyphenols

Abstract Metastasis of cells from primary site to distant organs involves a series of sequential steps, and molecules responsible for all these events are understandably considered as potential targets for metastasis management. Tea polyphenols, the secondary metabolites of the tea leaf Camellia sinensis, are increasingly being studied for their antimetastatic properties. In this article, effects of green tea polyphenols (GTP) and black tea polyphenols (BTP) on the molecules and events involved in metastasis are discussed in detail. As tea is a very popular beverage, tea polyphenols are expected to be potential chemopreventive agents that can be taken with normal diet and can be nontoxic due to their natural origin. However, individual variations in metabolic pathways, bioavailability, dose, and toxicity are some important factors that can modify the effectiveness of tea polyphenols within the human system.
Finite element analysis for simulating a hot thyroid nodule

Presents the theory supporting a new diagnostic method for a thermographic system. A finite element analysis of a hot thyroid nodule is developed and used for diagnosis utilizing thermal imaging. The new non-invasive diagnostic technique was applied to patients having Graves' diseases at the Indiana University (IU) Hospital, and compared with the existing scheme that utilizes I Scan. The results of the new diagnostic method were in very good agreement with the current existing method. The new technique is advantageous in that it can be safely applied to children and pregnant women, and is cost effective compared to the current techniques.
Study of Bipedal Robot Walking Motion in Low Gravity: Investigation and Analysis

Humanoid robots are expected to play a major role in the future of space and planetary exploration. Humanoid robot features could have many advantages, such as interacting with astronauts and the ability to perform human tasks. However, the challenge of developing such a robot is quite high due to many difficulties. One of the main difficulties is the difference in gravity. Most researchers in the field of bipedal locomotion have not paid much attention to the effect of gravity. Gravity is an important parameter in generating a bipedal locomotion trajectory. This research investigates the effect of gravity on bipedal walking motion. It focuses on low gravity, since most of the known planets and moons have lower gravity than earth. Further study is conducted on a full humanoid robot model walking subject to the moon's gravity, and an approach for dealing with moon gravity is proposed in this paper.
Understanding the association between spontaneous quit attempts and improved smoking cessation success rates: a population survey in England with six-month follow-up.

INTRODUCTION Almost half of smoking quit attempts are 'spontaneous' (initiated as soon as the decision to quit has been made) and are associated with increased success rates. This study aimed to assess to what extent other factors may account for this association. METHODS Data were used from respondents to a survey representative of the adult population in England from 2006 to 2016. We included 2,018 respondents who were current smokers at baseline and had attempted to quit between baseline and six-month follow-up. Logistic regression models assessed the association between quit success and spontaneous quit attempts while adjusting for smoking, sociodemographic and quit attempt characteristics. RESULTS Spontaneous quit attempts were associated with greater odds of quit success (OR=1.31, 95%CI=1.07-1.60) but the association was not significant in the fully adjusted model (ORadj=1.19, 95%CI=0.95-1.49). In this adjusted model, those who attempted to quit without cutting down first (ORadj=3.08, 95%CI=2.46-3.88) and were male (ORadj=1.44, 95%CI=1.16-1.80) had greater odds of success; while a greater number of attempts in the past 6 months, stronger urges to smoke (strong vs. none), higher daily cigarette consumption, and lower social grade (E vs. AB) were associated with lower odds of success (ORadj range=0.32-0.98, p<.030). Quit attempts made without cutting down first were correlated with spontaneous quit attempts (r=0.150, p<.001) and appeared to account for the diminished association between spontaneous quitting and success (ORadj=1.18, 95%CI=0.96-1.46). CONCLUSIONS The increased success rate of spontaneous quit attempts appears to be because spontaneous quit attempts are more likely to be made without cutting down first. IMPLICATIONS The apparent benefit of spontaneous over planned quit attempts may be attributable to the former being more likely to involve quitting without cutting down first (i.e. abrupt cessation) than cutting down first (i.e. gradual cessation) and so this may be a more useful target for advice to improve the chances of successful quitting.
Martha C. Pennington (ed.) (2007). Phonology in context . Basingstoke: Palgrave Macmillan. Pp. xii+317.

Throughout my experience as a linguist, the gulf between linguistic theory and most branches of applied linguistics has been wide. At graduate-school classes in the 1960s and 1970s, I was never invited to think about the evidence for general phonological theory that might be gleaned from (for example) developmental disorders in speech acquisition. I was aware that Fundamentals of language (Jakobson & Halle 1956) included some remarks by Roman Jakobson on aphasia, but I regarded that as mainly an illustration of Jakobson’s extraordinary polymathy, alongside his writings on Pushkin, Baudelaire and Yeats – a kind of interest that an ordinary linguist need not feel obliged to emulate. Later, I discovered ‘Natural Phonology’ (Donegan & Stampe 1979), with its emphasis on discourse contexts (attentive vs. inattentive articulation, speech rate and such like), but again I did not come away with the feeling that attention to such fine details of language-in-use was essential for phonology’s core business. This book is designed to shake the complacency of readers who share the somewhat blasé attitude that I have just described in myself. As Pennington puts it in her introductory chapter, ‘ the previous generation of linguists has perhaps been too quick to omake generalizations in the form of phonological rules that abstract away from the details of speech data’ (p. 13). Apart from the introduction, there are ten chapters: on phonological acquisition in infancy (Shelley L. Velleman & Marilyn M. Vihman), developmental phonological disorders (Fiona E. Gibbon), phonology in discourse contexts (Elizabeth Couper-Kuhlen) and in sociolinguistics (Paul Kerswill & Linda Shockey), contact phonology (Norval Smith), second-language phonology (Paola Escudero), the visual element in phonology (Debra M. Hardison), phonology and literacy (Keiko Koda), technological advances relevant to phonology (Dorothy M. Chun) and ‘sounds, brain and evolution’ (April McMahon). After reading the book, I am hard pressed to identify any phonological issue of which one can confidently say that none of the interfaces discussed in this book could ever be relevant to it. Consider even an issue that seems rather remote from ‘the details of speech data’, such as whether a particular morpho(phono)logical alternation should be handled phonologically or regarded as an instance of partial suppletion. Koda, in her chapter on phonology and literacy, discusses research on word-naming speed in languages with ‘shallow’ (phonetically transparent) orthographies, such as Spanish, and ones with ‘deep’ orthographies (which place more emphasis on consistent encoding of morphological units), such as Chinese and (allegedly) Hebrew. It is conceivable that work of the kind that Koda describes, despite its practical focus on acquiring L1 or L2 literacy, could turn out to have implications for fundamental theoretical issues at the morphology–phonology interface. Phonology 24 (2007) 486–488. f 2007 Cambridge University Press doi:10.1017/S0952675707001327 Printed in the United Kingdom
An immune infiltration signature to predict the overall survival of patients with colon cancer

Immune infiltration of tumors has been increasingly accepted as a prognostic factor in colon cancer. Here, we aim to develop a novel immune signature, based on estimated immune landscape from tumor transcriptomes, to predict the overall survival of patients with colon cancer. The compositions of 22 immune cell subtypes from three microarray datasets were characterized with the CIBERSORT deconvolution algorithm. A prognostic immunoscore (PIS) model for overall survival prediction was established by using least absolute shrinkage and selection operator (LASSO) penalized regression analysis. A total of 17 immune cell markers were screened out in the LASSO model and were then aggregated to generate the PIS. In the training cohort (n = 490), patients with high PIS exhibited a remarkably poorer overall survival than those with low PIS. Similar results were obtained in patients with different TNM stages and in patients receiving adjunctive chemotherapy or not. Multivariate Cox regression indicated that the PIS was an independent predictor for overall survival in colon cancer (hazard ratio: 2.734, 95% confidence interval: 2.052–3.643, p < .001). The prognostic capability of PIS was also confirmed in the testing cohort (n = 245) and the entire cohort (n = 735). As for biological implications, the PIS was significantly associated with some immune checkpoints, inflammatory factors, epithelial–mesenchymal transformation regulators, and many known signaling pathways in cancer. The results of our study provide a novel and promising immune signature for overall survival prediction of patients with colon cancer.
Social Pragmatics: Preschoolers Rely on Commonsense Psychology to Resolve Referential Underspecification.

Four experiments show that 4- and 5-year-olds (total N = 112) can identify the referent of underdetermined utterances through their Naïve Utility Calculus-an intuitive theory of people's behavior structured around an assumption that agents maximize utilities. In Experiments 1-2, a puppet asked for help without specifying to whom she was talking ("Can you help me? "). In Experiments 3-4, a puppet asked the child to pass an object without specifying what she wanted ("Can you pass me that one? "). Children's responses suggest that they considered cost trade-offs between the members in the interaction. These findings add to a body of work showing that reference resolution is informed by commonsense psychology from early in childhood.