Miracle-dz/UniFAR-FTUs huggingface dataset:
Handbook of Marine Craft Hydrodynamics and Motion Control

Technical and Research Symposium Society of Naval Architects and Marine EngineersMcGraw-Hill Encyclopedia of Science and TechnologyJane's High-speed Marine Craft and Air Cushion VehiclesNew York Port HandbookUndersea Technology Handbook, Directory无模型自适应控制兵法简述Marine Technology and SNAME News人月神話有限元方法Marine Robotics and Applications周易譯注余欢弹性固体中波的传播Aeroplane and Commercial Aviation NewsBulletin of the Permanent International Association of Navigation Congresses递推辨识的理论与实践Handbook of Marine Craft Hydrodynamics and Motion ControlTransactionsTransactions The Society of Naval Architects and Marine EngineersNaval Engineers JournalJane's High-speed Marine Craft核潜艇之旅生活的暗面食物恋Jane's Surface Skimmers美, 看不见的竞争力Mechanical Engineers' Handbook: Power; J. Kenneth Salisbury, editor离散时间控制系统概率, 随机变量与随机过程Government Reports Announcements & IndexMonthly Catalog of United States Government PublicationsDirectory of Special Libraries and Information Centers一個人住第9年Penny Stock HandbookHandbook on Selling to the U.S. MilitaryUnderwater Science and Technology Information Bulletin一个人流浪, 不必去远方The ProceedingsGovernment Reports Announcements
EFFECTS OF STAGE OF PREGNANCY AND LACTATION ON MAINTENANCE BEHAVIOUR OF DAIRY COWS AFTER HOUSING CHANGE

The aim of this study was to investigate the effects of time in days, pregnancy and lactation stage on behaviour of cows after change in type of housing. Forty eight hours long observation of 40 Holstein cows was done. The activities were registered at intervals of 10 minutes. The duration of total lying and ruminating increased (336.3 min. vs. 628.0 min., 318.0 min. vs. 325.4 min., P<0.001), the total time of standing decreased from the first day to the second day (1103.6 min. vs. 812.1 min., P<0.001). Number of periods of total lying, lying on the left and right side, and total ruminating also increased (P<0.001). The opposite course was recorded in the parameters of eating and total standing (P<0.001). No significant difference was noted in the stage of pregnancy factor, neither in duration of behaviour nor in number of periods. The longest total time of lying was observed in animals which were in lactation stage from 101 st to 200 th day (stage 2) (P<0.01). The longest times of eating and total standing were found in cows from the 1 st to 100 th day, and the shortest in cows classed in the stage 2. The highest number of periods of total lying (P<0.001), lying on the left and right sides were registered in cows which occurred in stage 2 (P<0.01).
Families of Chronic Psychiatric Patients

This study aims to investigate the studies conducted with the families of chronic psychiatric patients in Turkey and determine the characteristics and scope of future studies. In order to map out the recent studies conducted with the families of psychiatric patients in Turkey national and international databases were reviewed and eventually 26 studies were found to be suitable for inclusion. Of 26 studies reviewed, 7 studies were experimental and 19 studies were designed as descriptive in which certain reference points were defined such as mental health conditions of the family, family burden, quality of life, functionality, expressed emotions and their needs for education. On the other hand, the experimental studies mostly focused on the effects of various psychoeducation intervention programs particularly designed for care givers on patients and families. It was concluded that there is an obvious insufficiency in the number studies and researches on defining stress management levels and burdens of the families of chronic psychiatric patients as well as intervention programs specially designed for such families. Particularly designed invervention programs and studies are warranted.
Phase 1b/2, open label, multicenter study of intratumoral SD-101 in combination with pembrolizumab in anti-PD-1 treatment naïve patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).

6039 Background: SD-101, a synthetic CpG-ODN agonist of TLR9, stimulates dendritic cells to release IFN-alpha and mature into antigen presenting cells - activating T cell anti-tumor responses. Pembrolizumab has demonstrated activity in HNSCC. Study DV3-MEL-01 (NCT02521870) assesses safety and efficacy of SD-101 in combination with pembrolizumab in patients with recurrent/metastatic HNSCC. We have previously reported a 27.3% ORR in 22 patients receiving 8 mg SD-101/injection in the modified ITT after at least 2 CT scans due to late responses (Abstract 3560, ESMO 2018). Higher efficacy at a lower SD-101 dose, 2 mg/injection, has been reported in advanced melanoma patients (LBA 45, ESMO 2018). Consequently, this dose is now being assessed in HNSCC. We report preliminary data with the 2 mg/injection dose in 23 patients in mITT at the first CT scan. Methods: Anti-PD-1/PD-L1 naïve patients received 2 mg SD-101 intratumorally in 1 - 4 lesions (weekly x 4 doses then Q3W x 7 doses). Pembrolizumab is was administered IV at 200 mg Q3W. Responses were assessed per RECIST v1.1. Results: 28 patients enrolled: median age 63 y/o, male 68%; ECOG PS 0-1 (18%/82%); mean prior lines of systemic therapy 1 (0-3); mean treatment duration 70 days (1-253). Primary tumors: 19 (68%) oropharyngeal; 3 (10%) laryngeal; 2 (7%) hypopharyngeal; 4 (14%) unknown. Mean number of target lesions: 1.82 (1 to 5). HPV status: 7 (25%) +, 9 (32%) -, 12 (43%) unknown. 18 (64 %) discontinued treatment: 12 (42%) due to PD, 4 (16%) deaths, 1 (3%) consent withdrawn, 1 (3%) went to hospice. Mean follow up 2.70 months. Safety: 16 non-treatment-related SAEs in 9 patients. 2 treatment-related Grade ≥3 AEs: sepsis (4%) and lymphopenia (4% ). No treatment-related deaths. Efficacy: 23 patients in the mITT population with first CT scan at day 64: ORR: CR: 2, PR: 3 (22%); SD: 6 (26%), PD: 7 (30%), non-evaluable: 5 (22%). Disease control rate (48%). 5 patients on study have not had a CT scan. Conclusions: SD-101 with Pembrolizumab shows early promising data and is well tolerated. Additional follow-up scans from both dose cohorts are being evaluated and will be presented. Clinical trial information: NCT02521870.
The effect of childhood victimization in adults

Introduction: The experience of traumatic situations is related to psychological symptoms and disorders in adulthood [1]. The traumatic event with the greatest impact on children is the experience of sexual abuse [2]. This study aims to analyze the impact of childhood traumatic events on adults. Materials and methods: The sample is composed by 318 Portuguese adults. The majority of participants are female (n = 266, 83.6%), with ages between 18 and 89 years old (M = 29.69; DP = 13.23), most of them are single (n = 224, 70.4%) and high school graduated (n = 188, 59.1%). The participants responded online to the sociodemographic questionnaire, the Childhood Trauma Questionnaire (CTQ-SF) [3], Posttraumatic Stress Disorder Checklist (PCL-5) [4] and the Brief Symptom Inventory (BSI) [5]. The study was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki. Results: The correlation between the childhood trauma and the Posttraumatic Stress Disorder (PTSD) symptoms, showed some statistical significant results. The emotional abuse had significant and strong correlations with the symptoms of PTSD, for the total score (r = .42, p< .001) and the subscale reexperience (r = .33, p< .001), avoidance (r = .22, p< .001), hyperarousal (r = .44, p < .001), and duration (r = .38= p<.001). Concerning the sexual abuse, there were significant correlations with the total score (r = .13, p = .018), and the subscales avoidance (r = .20, p< .001) and hyperarousal (r = .15, p =.007). On physical abuse we verified significant correlations for the total score (r = .29, p< .001) and the subscales reexperience (r = .22, p< .001), avoidance (r = .11, p = .042), hyperarousal (r = .32, p < .001), duration (r = .28, p< .001). On emotional negligence, there are a significant correlation for the total score (r = −.30, p < .001) and subscales, reexperience (r = −.21, p < .001), avoidance (r = −.14, p = .015), hyperarousal (r = −.33, p< .001), duration (r = .30, p< .001). Comparing the traumatic events and symptomology between genders, the one-way ANOVA results showed that there were statistically significant differences between genders regarding sexual abuse [F (182.62) = −2.29, p = . 002], with women reporting greater exposure to sexual violence (M = 5.56, SD = 1.78). Regarding the symptomatology, there were statistically significant differences between genders, and women reported greater symptomatology than men. Discussion and conclusions: The childhood victimization can have negative consequences in the life of an adult, and it is important to implement an early intervention that makes it possible to prevent the beginning of psychopathological symptoms.
Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan

The Funadomari Jomon people were hunter-gatherers living on Rebun Island, Hokkaido, Japan c. 3500–3800 years ago. In this study, we determined the high-depth and low-depth nuclear genome sequences from a Funadomari Jomon female (F23) and male (F5), respectively. We genotyped the nuclear DNA of F23 and determined the human leukocyte antigen (HLA) class-I genotypes and the phenotypic traits. Moreover, a pathogenic mutation in the CPT1A gene was identified in both F23 and F5. The mutation provides metabolic advantages for consumption of a high-fat diet, and its allele frequency is more than 70% in Arctic populations, but is absent elsewhere. This variant may be related to the lifestyle of the Funadomari Jomon people, who fished and hunted land and marine animals. We observed high homozygosity by descent (HBD) in F23, but HBD tracts longer than 10 cM were very limited, suggesting that the population size of Northern Jomon populations were small. Our analysis suggested that population size of the Jomon people started to decrease c. 50000 years ago. The phylogenetic relationship among F23, modern/ancient Eurasians, and Native Americans showed a deep divergence of F23 in East Eurasia, probably before the split of the ancestor of Native Americans from East Eurasians, but after the split of 40000-year-old Tianyuan, indicating that the Northern Jomon people were genetically isolated from continental East Eurasians for a long period. Intriguingly, we found that modern Japanese as well as Ulchi, Korean, aboriginal Taiwanese, and Philippine populations were genetically closer to F23 than to Han Chinese. Moreover, the Y chromosome of F5 belonged to haplogroup D1b2b, which is rare in modern Japanese populations. These findings provided insights into the history and reconstructions of the ancient human population structures in East Eurasia, and the F23 genome data can be considered as the Jomon Reference Genome for future studies.
Experience with transformation of bibliographic data into linked data

Academic Bibliography Database of the University of Economics in Prague consists of bibliographic records of publications involving journal articles, conference papers, lecture notes, monographs and monograph chapters created by the academic staff of the university. We would like to discuss the experiences gained in the process of this dataset’s transformation from its current data format to RDF-based data. During the course of conversion we will specify the entity types in our data and choose a way to model them. For data description we are going to use the most popular and widely implemented vocabularies and domain ontologies. Next, we will discuss the issues associated with interlinking the data with relevant and well-established datasets constituting a part of the web of data (e.g., DBLP Computer Science Bibliography). We would like to examine further possibilities of data re-use by making the data suitable for other applications such as citation managers (e.g., Zotero) to generate citations automatically. We are also interested in providing users with the information about availability of a resource as full text or as library holding, so we discuss cooperation with link resolvers (SFX, in our case) as well as other possible ways of linking. In this way, aligned with the concept of the semantic web, we maintain that the potential of the data would be maximized, as the information in bibliographic records would become easy to share, more visible due to incoming links, and more ready to be processed by web applications. We argue that academic bibliography data should be openly available, so it increases transparency of publishing activity of the university’s academic staff. Beyond being re-usable, the data can be easily linked to so that they must not be duplicated at multiple locations. Likewise, these features together can provide a few benefits for bibliometric evaluation of science. The adoption of linked data publishing model for academic bibliography datasets involves moving to a more flexible data format for bibliographic data. While linked data is seen as a pragmatic implementation of the semantic web, we argue that it is not possible to implement the library data vision with the MARC, current standard for bibliographic data. Obviously, there is a need for more web-compatible and web-friendly data model. With this in mind, we suggest linked data as a part of the pragmatic implementation of the vision for bibliographic data on the Web.
Concurrent Queues: Practical Fetch-and-Phi Algorithms.

Abstract : With the growing use of multiprocessors, data structures that support concurrent operations have become increasingly important. In particular, algorithms and data structures for efficient implementation of concurrent queues have generated interest since operating systems heavily use queueing structures. Existing algorithms for managing concurrent queues all have drawbacks for practical implementation and use. This paper presents two practical implementations of a concurrent queue of unbounded length using fetch-and-phi primitives (a class of atomic read-modify-write operations) and argues their correctness. The first implementation provides wait-free enqueues with unbounded concurrency, although dequeues possess an inherently sequential component. The second implementation provides greater parallelism than existing algorithms and allows the user to trade space for potential parallelism. Both implementations satisfy the strong correctness criterion of linearizability whereas existing algorithms with similiar properties do not.
Impact of misuse of antimicrobial agents on egg bitterness

A hundred raw eggs samples randomly selected from Aswan university residence restaurant due to students' complain of bitter taste presence in the table eggs served to them during breakfast. The samples were examined physically and chemically for antibiotic residues and vitamins A, D3 levels concentration by Spectrophotometer. The result showed that all interior egg quality traits were normal except the presence of small blood spots in 5 eggs yolk, bitter taste were present in 18 eggs yolk, antimicrobial residues were detected in 19 eggs yolk and 4 eggs white. Antimicrobial residues positive samples were examined quantitatively by HPLC for Doxycycline (DC) residues presence. The results showed that 100% of examined samples having DC residues with means concentrations of 35±1.46 and 97±4.46 ppb for eggs white and yolk respectively. The mean levels of vitamin A and D3 in eggs yolk were 447±5.49 µg/100g and11±1.35 µg/100g respectively. The paper concludes that the high concentrations of Vitamins and Doxycycline may be the cause of bitter taste of egg.
Modeling Optimal Values of the Traffic Load-Based Factors over Performance of LTE Cellular and 802.11ac

The load-based features of the traffic particularly in resource-limited wireless systems, including LTE and 802.11ac, are among the primary factors that any changes in their values can directly affect the efficiency of the networks. Keeping in mind the fact that proper selection of the parameters is very crucial for performance optimisation of the networks, this work proposes a comprehensive framework called loadbased factors (LBF) with two main purposes. First, to quantify and determine the effects of the load- based parameters including traffic source rate, traffic type, and packet size on the performance of LTE and 802.11ac networks. Second, to accurately determine the actual effective values of these parameters and achieve the performance optimality in both LTE and 802.11ac networks. The NS3 tool is used to implement and evaluate the LBF framework. The experimental results show that the proposed framework by varying these parameters and testing the corresponding impacts via implementing a wide range of scenarios and experiments can be used as a comprehensive model to determine and compare the optimal values of these parameters in both LTE and 802.11ac networks.
MOUSE MODELS OF CHRONIC TOXOPLASMA GONDII (T. GONDII) INFECTION: IMPLICATIONS FOR PSYCHIATRIC DISEASE

Gene-environment interactions (GEI) likely play significant roles in the pathogenesis of schizophrenia and underlie differences in pathological, behavioral, and clinical presentations of the disease. Findings from epidemiology and psychiatric genetics have assisted in the generation of animal models of GEI relevant to schizophrenia. These models may provide a foundation for elucidating the molecular, cellular, and circuitry mechanisms that mediate GEI in schizophrenia. Here we critically review current mouse models of GEI related to schizophrenia, describe directions for their improvement, and propose endophenotypes provide a more tangible basis for molecular studies of pathways of GEI and facilitate the identification of novel therapeutic targets.
A Danger Theory Based Immune Network Dynamic Optimization Algorithm

Although the existing artificial immune dynamic optimization algorithms have dynamic tracking abilities, but the errors are large. This paper proposes a danger theory based immune network dynamic optimization algorithm, named ddt-aiNet. By defining the danger zone to calculate danger signals for each antibody, the algorithm adjusts antibodies’ concentrations through their own danger signals, which triggers immune responses of self-regulation. So the population diversity can be maintained. And the algorithm sets detection antibodies in the solution space. Through monitoring the danger signals of these detection antibodies, the algorithm can perceive the environmental changes, and then re-initialize the population in proportion. Experimental results show that the algorithm is better than the classical dynamic optimization algorithm dopt-aiNet. It has smaller errors, and can better track the environmental changes.
Automated Listing for Exportable Products

Business plays a pivotal role for the development of human civilization as well as change of the status of the country in this whole universe. To compare and compute the export trend for any organization or a country is an indispensable for numerous intelligent systems to measure the national and international gain or loss for developing countries as well as for developed countries. The main purpose of this research is to develop a dynamic business prediction model for person, organization, Institute, Ministry of Commerce, Ministry of Finance ,Ministry of Economics, Prime Minister office and last but not least for whole world to predict the exact demand for exportable products and formulate export policy. Bangladesh Export Promotion Bureau (BEPB) helped us by providing the valuable data set and information. In this research activities we have had first classify the data by using Support Vector Machine (SVM), a latest data classification technique in the field of data processing. SVM reduce the redundant data from vast amount of data. After getting processed data we have used first-order logic (FL) to build a knowledgebase which will work as background knowledge for our computation. Finally Bayes’ Network (BN) has used to perform the proper prediction by using the knowledge base information. Based on the result of BN, we have made a list of emerging products those have major impact on the prosperity of the country or organization.
Artificial Intelligence and the Implementation Challenge

Background Applications of artificial intelligence (AI) in health care have garnered much attention in recent years, but the implementation issues posed by AI have not been substantially addressed. Objective In this paper, we have focused on machine learning (ML) as a form of AI and have provided a framework for thinking about use cases of ML in health care. We have structured our discussion of challenges in the implementation of ML in comparison with other technologies using the framework of Nonadoption, Abandonment, and Challenges to the Scale-Up, Spread, and Sustainability of Health and Care Technologies (NASSS). Methods After providing an overview of AI technology, we describe use cases of ML as falling into the categories of decision support and automation. We suggest these use cases apply to clinical, operational, and epidemiological tasks and that the primary function of ML in health care in the near term will be decision support. We then outline unique implementation issues posed by ML initiatives in the categories addressed by the NASSS framework, specifically including meaningful decision support, explainability, privacy, consent, algorithmic bias, security, scalability, the role of corporations, and the changing nature of health care work. Results Ultimately, we suggest that the future of ML in health care remains positive but uncertain, as support from patients, the public, and a wide range of health care stakeholders is necessary to enable its meaningful implementation. Conclusions If the implementation science community is to facilitate the adoption of ML in ways that stand to generate widespread benefits, the issues raised in this paper will require substantial attention in the coming years.
The effect of applying pressure to the third liver point on the symptoms of involved liver channel in girls with primary dysmenorrhea: A randomized clinical trial

Background: Primary dysmenorrhea is one of the most prevalent disorders in women which results in their decreased efficacy. The aim of this study is to evaluate the effect of pressure on the third liver point on involved liver channel symptoms in patients with primary dysmenorrhea. Materials and Methods: This clinical trial was conducted on 194 students that met the inclusion criteria. In the first cycle, symptoms of involved liver channel were identified. Accordingly, participants were randomly allotted to either treatment or control groups. In the second, third and fourth cycles, acupressure was applied to the third liver point and placebo point for 20 minutes 3-7 days before menstruation. With bleeding in the fourth cycle, the symptoms of involved liver channel were determined. Results: In the first cycle, there were no significant differences in symptoms of involved liver channel between the two groups; however, in the fourth cycle, the results of Chi 2 test showed significant differences between the two groups in all symptoms of involved liver channel except the tongue with red spots (p<0.05). In the treatment group, a comparison of the first and the fourth cycle revealed significant differences in all symptoms of involved liver channel except for tongue with red spots (p<0.05). Conclusion: In this study, applying pressure to the third liver point was effective in the improvement of the majority of involved liver channel symptoms; therefore, acupressure is suggested as a practical, effective, non-expensive, and available method in the treatment of primary dysmenorrhea.