Miracle-dz/UniFAR-FTUs huggingface dataset:
An RF Energy Harvester With 44.1% PCE at Input Available Power of -12 dBm

A 900-MHz radio-frequency energy harvester is designed and implemented for remotely powered devices. An efficient power path structure with adaptive control is proposed to maintain close-to-optimal power conversion efficiency. The control circuit consumes low power by adopting a novel open-loop asynchronous implementation and duty-cycled operation. A startup circuit is also presented. Measurement results show minimum input available power for startup of -17 dBm. With input available power of -12 dBm and load resistance of 144 kΩ, the measured output power is 27.8 μW, giving an output voltage of 2 V. This corresponds to an end-to-end power conversion efficiency of 44.1%. The harvester consumes quiescent current of 1.56 μA at output voltage of 2 V.
Shaken baby syndrome in Canada: clinical characteristics and outcomes of hospital cases.

BACKGROUND Shaken baby syndrome is an extremely serious form of abusive head trauma, the extent of which is unknown in Canada. Our objective was to describe, from a national perspective, the clinical characteristics and outcome of children admitted to hospital with shaken baby syndrome. METHODS We performed a retrospective chart review, for the years 1988-1998, of the cases of shaken baby syndrome that were reported to the child protection teams of 11 pediatric tertiary care hospitals in Canada. Shaken baby syndrome was defined as any case reported at each institution of intracranial, intraocular or cervical spine injury resulting from a substantiated or suspected shaking, with or without impact, in children aged less than 5 years. RESULTS The median age of subjects was 4.6 months (range 7 days to 58 months), and 56% were boys. Presenting complaints for the 364 children identified as having shaken baby syndrome were nonspecific (seizure-like episode [45%], decreased level of consciousness [43%] and respiratory difficulty [34%]), though bruising was noted on examination in 46%. A history and/or clinical evidence of previous maltreatment was noted in 220 children (60%), and 80 families (22%) had had previous involvement with child welfare authorities. As a direct result of the shaking, 69 children died (19%) and, of those who survived, 162 (55%) had ongoing neurological injury and 192 (65%) had visual impairment. Only 65 (22%) of those who survived were considered to show no signs of health or developmental impairment at the time of discharge. INTERPRETATION Shaken baby syndrome results in an extremely high degree of mortality and morbidity. Ongoing care of these children places a substantial burden on the medical system, caregivers and society.
Should raising high-density lipoprotein cholesterol be a matter of debate?

High-density lipoprotein cholesterol (HDL-C) has been identified as an independent inverse predictor of coronary heart disease, leading to the inclusion of HDL-C in certain risk engines. However, negative results also exist and create confusion regarding the value of interventions that increase HDL-C. The possible reasons for these conflicting findings are many, including not only patient selection (e.g. baseline HDL-C levels) but also the effect of the treatment on the quantity and quality of HDL. In the present review, the results of some HDL-C trials are discussed. They suggest that HDL-C function as well as quantity is clinically relevant. Furthermore, ‘dysfunctional’ HDL may be present in conditions such as diabetes or acute coronary syndromes. Efforts should focus on improving HDL particle functionality in addition to a numerical increase in HDL-C levels.
Differential regulation of rat beta-casein-chloramphenicol acetyltransferase fusion gene expression in transgenic mice

Previous studies in our laboratory have demonstrated the mammary-specific expression of the entire rat beta-casein gene with 3.5 kilobases (kb) of 5' and 3.0 kb of 3' DNA in transgenic mice (Lee et al., Nucleic Acids Res. 16:1027-1041, 1988). In an attempt to localize sequences that dictate this specificity, lines of transgenic mice carrying two different rat beta-casein promoter-bacterial chloramphenicol acetyltransferase (cat) fusion genes have been established. Twenty and eight lines of transgenic mice carrying two fusion genes containing either 2.3 or 0.5 kb, respectively, of 5'-flanking DNA of the rat beta-casein gene along with noncoding exon I and 0.5 kb of intron A were identified, most of which transmitted the transgenes to their offspring in a Mendelian pattern. CAT activity was detected predominantly in the lactating mammary gland of female transgenic mice but not in the male mammary fat pad. A several-hundred-fold variation in the level of cat expression was observed in the mammary gland of different lines of mice, presumably due to the site of integration of the transgenes. CAT activity was increased in the mammary gland during development from virgin to midpregnancy and lactation. Unexpectedly, the casein-cat transgenes were also expressed in the thymus of different lines of both male and female mice, in some cases at levels equivalent to those observed in the mammary gland, and in contrast to the mammary gland, CAT activity was decreased during pregnancy and lactation in the thymus. Thus, 0.5 kb of 5'-flanking DNA of the rat beta-casein gene along with noncoding exon I and 0.5 kb of intron A are sufficient to target bacterial cat gene expression to the mammary gland of lactating mice.
Fall Detection using Head Tracking and Centroid Movement Based on a Depth Camera

The number of elderly people living alone has increased over the las1t years and fall is one of major risks that threaten their lives. A fall detection system has become a requirement and computer vision is an efficient solution among many accurate solutions developed in this field. This paper proposes a novel method vision-based fall detection using depth camera, which combines human shape analysis, head tracking and centroid detection to validate falls. An experimental test done with SDUFall dataset which contains 20 subjects performing five daily activities and falls demonstrates the efficiency of our method, achieving up to 93.25% accuracy compared with the state-of-the-art method using the same dataset.
ARTEMIS observations of lunar pickup ions: Mass constraints on ion species

Observations of heavy ions of lunar origin give important information regarding lunar exospheric processes, especially with respect to exospheric particle abundance and composition. Electrostatic analyzers without a time‐of‐flight section provide highly sensitive, absolute density detection but without mass discrimination. Here we place constraints on lunar ion species through inference of the average ion mass using such instruments. The technique is based on the plasma quasi‐neutrality requirement, an independent electron density measurement, and the fact that electrostatic analyzers underestimate the ion density by the square root of the ion mass. Applied to a case of such observations by ARTEMIS in the terrestrial lobe reported by Poppe et al. (2012), our technique suggests an average mass of 28 amu for lunar pickup ions. This result, consistent with the lower limit of 24 amu derived in the Poppe et al. model, suggests that the observed ions were most likely Al+ and Si+. The technique is also refined and applied to a more complicated event with a series of heavy ion surges in the plasma sheet, to show the spatial and/or temporal dependence of the observed lunar ion species. The technique is particularly timely given the planned conjunctions and coordinated lunar studies by NASA's Acceleration, Reconnection, Turbulence and Electrodynamics of the Moon's Interaction with the Sun (ARTEMIS) and Lunar Atmosphere and Dust Environment Explorer missions.
Correction in trans for Fabry disease: expression, secretion and uptake of alpha-galactosidase A in patient-derived cells driven by a high-titer recombinant retroviral vector.

Fabry disease is an X-linked metabolic disorder due to a deficiency of alpha-galactosidase A (alpha-gal A; EC 3.2.1.22). Patients accumulate glycosphingolipids with terminal alpha-galactosyl residues that come from intracellular synthesis, circulating metabolites, or from the biodegradation Of senescent cells. Patients eventually succumb to renal, cardio-, or cerebrovascular disease. No specific therapy exists. One possible approach to ameliorating this disorder is to target corrective gene transfer therapy to circulating hematopoietic cells. Toward this end, an amphotropic virus-producer cell line has been developed that produces a high titer (>10(6) i.p. per ml) recombinant retrovirus constructed to transduce and correct target cells. Virus-producer cells also demonstrate expression of large amounts of both intracellular and secreted alpha-gal A. To examine the utility of this therapeutic vector, skin fibroblasts from Fabry patients were corrected for the metabolic defect by infection with this recombinant virus and secreted enzyme was observed. Furthermore, the secreted enzyme was found to be taken up by uncorrected cells in a mannose-6-phosphate receptor-dependent manner. In related experiments, immortalized B cell lines from Fabry patients, created as a hematologic delivery test system, were transduced. As with the fibroblasts, transduced patient B cell lines demonstrated both endogenous enzyme correction and a small amount of secretion together with uptake by uncorrected cells. These studies demonstrate that endogenous metabolic correction in transduced cells, combined with secretion, may provide a continuous source of corrective material in trans to unmodified patient bystander cells (metabolic cooperativity).
COMPARING INDEXES OF FRAILTY: THE CARDIOVASCULAR HEALTH STUDY AND THE STUDY OF OSTEOPOROTIC FRACTURES

intravenous bisphosphonate treatment, although this did not translate into detectable improvements in rehabilitation outcomes, which may have been because of insufficient responsiveness of these outcome measures and possibly because of the small doses of vitamin D supplemented and short duration of the study. With regard to the optimal dosage of vitamin D after hip fracture, a daily oral vitamin D replacement was shown to be more effective in improving 25OHD levels after 1 year than 300,000 IU D2 intramuscularly once yearly, suggesting the benefits of ongoing vitamin D supplementation. According to the results of the current study, we would advocate a vitamin D replacement protocol similar to that of a previous study, consisting of an initial parenteral loading dose (50,000–125,000 IU intramuscularly) within 10 days of hip fracture, followed by daily oral vitamin D (800–1,200 IU) and calcium (1,000– 1,500 mg daily). We would also advocate for a large-dose parenteral vitamin D formation to be made available in Australia, because this is not currently available. Further studies are required to ascertain whether a larger initial loading dose of parenteral vitamin D can translate into improvements in rehabilitation outcomes.
Transient osteoporosis of the hip in pregnancy: natural history of changes in bone mineral density

A 31‐year‐old white female developed severe bilateral hip pain during the third trimester of pregnancy that persisted after parturition. Laboratory abnormalities (elevated alkaline phosphatase and erythrocyte sedimentation rate) and radiographic changes (faint demineralization of the femur in the more symptomatic hip on plain films with evidence of bone marrow oedema and small joint effusions bilaterally on MRI) in the absence of other causes of focal osteoporosis were consistent with the diagnosis of transient osteoporosis of the hip in pregnancy. Although loss of bone mineral density (BMD) characterizes this syndrome, serial BMD measurements in symptomatic transient osteoporosis of the hip in pregnancy have not previously been reported. In the case reported here, serial bone density measurements were obtained over a 4‐year period following the onset of symptoms. BMD in both femoral necks, which Initially was approximately 20% lower than the average for age matched controls, increased markedly during the first year, plateaued during the following year, and then rapidly increased again following cessation of lactation. Unexpectedly, BMD in the lumbar spine, an asymptomatic site, was also markedly decreased at the time of presentation (31% lower than the mean of age‐matched controls). Recovery of spinal density did not occur during the first year. However, spinal BMD did begin to increase during the second year and continued to rise after the cessation of lactation. In contrast to the marked reduction in bone density at these sites of trabecular bone, cortical bone density in the forearm was normal. Possible aetiologies of pregnancy associated osteoporosis are discussed.
Avaliação Curricular e Paradigmas

O artigo comeca por destrincar a avaliacao curricular da avaliacao de aprendizagem dos alunos, recorrendo a circularidade do modelo tecnologico. Apos discutir o conceito de paradigma, procede a um levantamento de alguns modelos de avaliacao curricular, desde os situados num paradigma quantitativo, que visa a explicacao das situacoes, na sua forma mais pura, absoluta e objetiva, nao contaminada pelas percepcoes e concepcoes do avaliador, ate ao paradigma qualitativo, que pretende a compreensao da “realidade” em causa, devidamente contextualizada, fazendo uso das subjetividades, obrigando por isso o avaliador a uma imersao mais profunda no terreno de avaliacao. Finalmente toma uma posicao critica e fundamentada na teoria anteriormente exposta, defendendo o exercicio de autoavaliacao.
Dos contribuciones sobre la estabilidad y el determinismo de los sistemas

La observacion principal de Ilya Prigoine, tal como la desarrolla en Las leyes del caos (1993), es que la ciencia natural contemporanea pone de manifiesto la existencia del azar y del caos en la constitucion de la mayoria de los sistemas dinamicos; afirma que tales sistemas son una mezcla irreductible de determinismo y de azar. El quimico ruso contrapone asi su interpretacion de la ciencia contemporanea -actividad consciente del indeterminismo y de la irreversibilidad temporal creadora, y que por eso estaria en lo cierto- a la ciencia moderna que habria estado, segun el, condicionada por un tiempo reversible conservador y erroneamente orientada hacia el determinismo. Por su parte, la contribucion principal del fisico frances Theodore Vogel en su obra Por una teoria mecanicista renovada (1973) consiste en mostrar que no existe mejor modelo cientifico que el mecanicismo. Este modelo presupone la estabilidad de los sistemas, la relacion causal, el determinismo, y se enracina en la esperanza de que las matematicas, la herramienta principal del pensador mecanicista, permitiran renovar las categorias mecanicistas y reducir, en consecuencia, las areas de indeterminacion. Ahora bien, yo no adopto una actitud neutra en esta oposicion de filosofias de la ciencia natural sino que intento criticar las ideas de Prigogine y poner de relieve el valor de la posicion de Vogel.
Discrimination of geographical origin and adulteration of radix astragali using fourier transform infrared spectroscopy and chemometric methods.

INTRODUCTION Radix Astragali, one of most widely used and important traditional Chinese medicines, is cultivated in different geographical regions. Because of varying growing conditions, the qualities of Radix Astragali vary, which can give rise to differences in clinical therapy. Detecting adulteration is a routine requirement in pharmaceutical practice. OBJECTIVE To develop a simple and accurate approach to discriminate the geographical origin and potential adulteration of Radix Astragali, derived from the root of Astragalus membranaceus (Fischer) Bunge var. mongholicus (Bunge) Hsiao, using Fourier transform infrared (FT-IR) spectroscopy and chemometric methods. METHODOLOGY To obtain characteristic IR spectra for accurate discrimination, a one-solvent extraction method was utilised following a novel evaluation method for selecting appropriate solvents. Samples of Radix Astragali from different geographical origins were discriminated using FT-IR spectroscopy and discriminant partial least squares (DPLS) methods. FT-IR spectroscopy combined with Mahalanobis distance was employed to detect adulteration of Radix Astragali. RESULTS In comparison with other solvents, butanone was more effective at extracting samples. Radix Astragali samples were accurately assigned to their corresponding geographical origins by using FT-IR spectroscopy and DPLS method. Most adulterated samples were detected accurately by application of FT-IR spectroscopy combined with Mahalanobis distance. CONCLUSION FT-IR spectroscopy combined with chemometric method was developed and demonstrated to be a useful tool to discriminate geographical origin and adulteration of Radix Astragali.
Supporting Visual Analysis in Smart Meeting Rooms

Smart meeting rooms as a specific form of multi-display environments (MDE) feature ad-hoc ensembles of heterogeneous devices and software tools to facilitate collective work and information sharing between multiple users. This makes them excellent environments for supporting visual analytics sessions. Effective use of MDE requires not only appropriate visual representations of the information needed by each user for her current task but also the efficient utilization of available display space by means of suitable view management. In this paper, we propose a task-driven approach to Smart View Management that combines automated task-based view configuration with interactive user specification of selected analysis task aspects. It is based on a general task typology capable of expressing the role of individual data views with respect to a given, possibly compound analysis task. The feasibility of the proposed approach is discussed by virtue of a use case from the climate impact research domain.
Introduction d’une théorie des jeux dans des topologies dynamiques :

L'objet de cette these est de presenter une methode de modelisation de la complexite. Partant de l'analyse tensorielle des reseaux, on montre tout d'abord que cette technique permet de modeliser tout processus physique en integrant dans un formalisme efficace les modeles developpes dans chaque branche actuelle de la physique. Il ne s'agit pas de proposer une methode universelle, mais bien un formalisme qui est capable d'integrer et de coupler les modeles developpes par ailleurs et appeles a evoluer. Le formalisme encapsule ainsi ceux de la mecanique quantique ou de la relativite generale, etc. L'aspect "physique" du systeme pris en charge, on fait appel a la theorie des jeux pour aborder l'aspect "psychique" du systeme, pour modeliser son comportement. Ce lien passe par la creation d'objets mathematiques comme les tenfolds et gamma matrices. On est alors a meme de creer un arbre d'evolution et de representer des trajectoires de transformations et decisions dans un espace "choix-gains".
Molecular weight distribution changes during degradation and release of PLGA nanoparticles containing epirubicin HCl

The molecular dynamics of the degradation process of poly(lactic-co-glycolic acid) nanospheres were investigated during the degradation process usually observed when these polymers are used as controlled release carriers. The molecular weight distribution of PLGA samples was determined over a period of 32 days by accurately analyzing the molecular weight distribution of the polymer as a function of time as degradation progressed. The molecular weight distribution shifted gradually to lower average molecular weights over 32 days, with significantly smaller molecular weight components appearing at 8–12 days. In addition, the degradation of nanospheres containing epirubicin HCl was analyzed and increasing the amount of epirubicin from 1.7 to 3.4 to 6.7 wt% was found to hasten the degradation of the nanoparticles and subsequently affect the release behavior from these particles. This is believed to be the first time that such molecular dynamics have been presented for the degradation of PLGA nanoparticle formulations containing a drug for controlled delivery.
Matter and form in early modern science and philosophy

Preface List of Contributors List of illustrations Three Biased Reminders about Hylomorphism in Early Modern Science and Philosophy, Gideon Manning Body, Soul and Anatomy in Late Aristotelian Psychology, Michael Edwards Living Atoms, Hylomorphism and Spontaneous Generation in Daniel Sennert, Hiro Hirai Elective Affinity Before Geoffroy: Daniel Sennert's Atomistic Explanation of Vinous and Acetous Fermentation, William R. Newman Substantial Forms as Causes: From Suarez to Descartes, Tad Schmaltz Mechanizing the Sensitive Soul, Gary Hatfield Descartes and His Critics on Matter and Form, Atomism and Individuation, Roger Ariew Spirit is a Stomach: The Iatrochemical Roots of Leibniz's Theory of Corporeal Substance, Justin Smith Leibnizian Hylomorphism, Daniel Garber Index
2RW dual-port SRAM design challenges in advanced technology nodes

We examine appropriate bitcell layouts for two read/write (2RW) 8T dual-port (DP) SRAM in advanced planar/FinFET technologies. 256-kbit 2RW DP SRAM macros with highly symmetrical 8T DP bitcell were designed and fabricated using 16 nm FinFET technology. The read/write assist with wordline overdrive reduces Vmln by 120 mV, achieving successful operation at below 0.5 V.
Students' experiences and attitudes towards learning computer science

Low enrollment and high drop-out rates in computer science (CS) have led to an alarming decrease in number of graduates in western countries. What are students' learning experiences, how do these affect their attitudes towards learning CS? This question was explored by investigating diverse students, of a broad study program with courses in humanities and technology, at the end of an introductory course in CS (CS1), which has been designed to enhance students' engagement. The results of a first questionnaire were remarkably positive: All students reflected their experiences as overall positive. Almost half of the students stated, that they had been skeptical towards learning CS before the course. All of these students described positive transformations of attitudes. These results provided an interesting starting point for further research using interviews: What exactly have these students experienced and how do they reason about future engagement? We point out students' experiences that were crucial for a positive transformation of attitudes as well as critical aspects in students' reasoning on future engagement in CS.
Expression of mucin (MUC) genes in mucoepidermoid carcinoma

Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor. The presence of mucin (MUC) genes has been correlated with patient prognosis using immunohistochemical techniques. This study was undertaken to 1) investigate the expression of newly discovered MUC genes in MEC specimens, 2) assess the correlation of this expression to prognosis, and 3) further investigate the correlation of previously identified MUC genes to prognosis using molecular techniques.