Miracle-dz/UniFAR-FTUs huggingface dataset:
Molecular Studies on E.Coli Isolate from Milk of Mastatic Cattle with Special Reference to Associated Biochemical Changes in Kaliobea Governorate

This investigation was performed in Teaching hospital and farm of Benha university in Moshtohor the number of cows in this farm 80 dairy cows that 40 of them had clinical signs of mastitis (inflammation in teats, pain in milking and milk decrease in amount and quality). When examine these cows to identify the disease which cause these signs. California Mastitis Test (CMT) was performed to determine positive milk samples in the Mastitic targeted cows. 20 samples of early lactation stage cows out of 40 samples recovered from CMT- positive milk samples. Biochemical and PCR tests were performed to isolates E. Coli from positive milk samples (CMT) and determined three virulance genes, eae gene, SXT1 and SXT2. The significance of Escherichia coli-induced mastitis and biochemical changes associated to it in cows, due to the presence of virulence genes and wide range resistance to 20 antimicrobials, is concluded. E.coli cause biochemical changes in mastatic cow as (liver enzymes AST, GPT, TP, ant. oxidative enzymes as CAT, SOD, GST, LD and kidney function as urea and creatinine. E.coli has effect on inflammatory response in immunity system of mastitic cow by increase IL6, TNF and CRP.
A new C–C bond formation model based on the quantum chemical topology of electron density

ELF topological analyses of bonding changes in non-polar, polar and ionic organic reactions involving the participation of CC(X) double bonds make it possible to establish a unified model for C–C bond formation. This model is characterised by a C-to-C coupling of two pseudoradical centers generated at the most significant atoms of the reacting molecules. The global electron density transfer process that takes place along polar and ionic reactions favours the creation of these pseudoradical centers at the most nucleophilic/electrophilic centers of the reacting molecules, decreasing activation energies. The proposed reactivity model based on the topological analysis of the changes in electron density throughout a reaction makes it possible to reject the frontier molecular orbital reactivity model based on the analysis of molecular orbitals.
Ontological Representation of Relational Databases

Relational database systems is a well-known domain and an essential component of life in modern society. However, a well-founded ontological conceptualization of this domain is not yet defined and shared by the community, nor applied as a solution to problems such as semantic interoperability, database migration, etc. In this paper, we present RDBS-O, a well-founded reference ontology on the relational database domain, rigorously constructed, verified and validated according to an ontology engineering method. In addition to a reference ontology, we also implement and test its operational version, using it to automatic instantiate the ontology from a real database sample.
Dependent Species Sampling Models for Spatial Density Estimation

We consider a novel Bayesian nonparametric model for density estimation with an underlying spatial structure. The model is built on a class of species sampling models, which are discrete random probability measures that can be represented as a mixture of random support points and random weights. Specifically, we construct a collection of spatially dependent species sampling models and propose a mixture model based on this collection. The key idea is the introduction of spatial dependence by modeling the weights through a conditional autoregressive model. We present an extensive simulation study to compare the performance of the proposed model with competitors. The proposed model compares favorably to these alternatives. We apply the method to the estimation of summer precipitation density functions using Climate Prediction Center Merged Analysis of Precipitation data over East Asia.
The work-to-family conflict: Theories and measures

The work-family conflict is a topic of increasing interest in psychological research: many are the theoretical speculations as well as the attempts to provide adequate measuring instruments. In Italy the few studies devoted to this topic mostly use Netemeyer et al. (1996) scale, which measures the workfamily and family-work conflict. This study reviews the theories on the work-family interface and proposes an adjustment of Netemeyer et al.’s instrument. The adjusted scale was submitted to a sample of 369 people. Its psychometric characteristics are presented in terms of factor structure, reliability, and capability of differentiating among different individuals. The results of the data analysis are in line with the indications in the literature. Factor analysis confirms the distinction between the conflicts work versus family as opposed to family versus work. The adaptation of Netemeyer et al.’s instrument presents overlapping characteristics with the original version.
The diversity of antifungal compounds of six South African Terminalia species (Combretaceae) determined by bioautography

A bioautography method was developed to determine the number of antifungal compounds in Terminalia species extracts. Acetone, hexane, dichloromethane and methanol leaf extracts of six Terminalia species (T. prunioides, T. brachystemma, T. sericea, T. gazensis, T. mollis and T. sambesiaca) were tested against five fungal animal pathogens (Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus, Microsporum canis and Sporothrix schenkii). The Rf values and relative activities of separated compounds were determined. Hexane and dichloromethane extracts had at least three times more antifungal compounds than the other extracts indicating the nonpolar character of the antifungal compounds. From the Rf values, the non-polar character of the antifungal compounds was confirmed indicating that the antifungal activity is not due to tannins. M. canis had the highest number, up to ten, of antifungal compounds. All Terminalia species contained a compound (Rf =0.46 in benzene/ethanol/ammonium hydroxide (90/10/1) active against all tested pathogens. T. sericea and T. brachystemma were the most promising candidates for isolating antifungal compounds. The results demonstrate the value of bioautography in examining plant extracts with antifungal activity, selecting species for further study and dereplicating the isolation of compounds.
Improving branching for disjunctive polyhedral models using approximate convex decompositions

Disjunctive sets arise in a variety of optimization models and much esearch has been devoted to obtain strong relaxations for them. This paper focuses on the evaluation of the relaxation during the branch-and-bound search process. We argue that the branching possibilities (\ie binary variables) of the usual formulations are unsuitable to obtain strong bounds early in the search process as they do not capture the overall shape of the the entire disjunctive set. To analyze and exploit the shape of the disjunctive set we propose to compute a hierarchy of approximate convex decompositions and show how to extend the known formulations to obtain improved branching behavior.
Saber: Delegating Web Security to Browser

Today, any non-trivial application requires the ability to communicate over the network. Providing a secure connection (i.e., a confidential and authenticated connection) is a difficult task as it involves correctly implementing complex protocols. Having stood the test of time as being the most popular application for network communication, browsers have been able to achieve network security with greater success. However, almost all other non-browser applications have lagged behind. We look at tools that fetch webpages over https (such as wget), analyze their connection security, and propose that these tools delegate network security to browsers. Furthermore, we built a prototype version of wget to demonstrate the feasibility of building applications that provides security guarantees (confidentiality, integrity, authenticity) without requiring a deep understanding of the TLS protocol.
The Money Pump as a Measure of Revealed Preference Violations: A Comment

In a recent and insightful paper, Echenique et al. [4] proposed the Money Pump Index(MPI) as an intuitive measure to evaluate the severity of violations of consumer rationality(defined in terms of revealed preference axioms). For practical applications, they suggest usingthe Mean or Median MPI. In this note, we show that computing these Median and Mean MPIis computationally hard, which makes them impractical in the case of large datasets (including"scanner" datasets as the one used by Echenique et al.). To overcome this problem, we proposeMaximum and Minimum MPIs as easy-to-apply alternatives. These MPIs preserve the intuitionof the Median and Mean MPIs and can be computed efficiently (i.e. in polynomial time). Wealso show the practical usefulness of the Maximum and Minimum MPI through an applicationto the dataset of Echenique et al.
A Survey Paper of Distributed Denial-of-Service Attack in Software Defined Networking (SDN)

Distributed Denial of Services (DDoS) attacks is one of well-known and dangerous threats to the current network which always exists and evolves in line with the development of the network itself. Current network development has entered the Software Defined Networking (SDN) era which offers centralized control and programmability network by decoupling the network control and data plane that bring on us a dynamic, cost-effective, manageable and agile platform. On the down-side, this centralized platform can bring new security challenges such as DDoS attacks on the central controller which could compromise the entire network. This paper presents security challenge on SDN and provides several approaches to mitigate the DDoS attack from various source.
Salience, Credibility, Legitimacy and Boundaries: Linking Research, Assessment and Decision Making

The boundary between science and policy is only one of several boundaries that hinder the linking of scientific and technical information to decision making. Managing boundaries between disciplines, across scales of geography and jurisdiction, and between different forms of knowledge is also often critical to transferring information. The research presented in this paper finds that information requires three (not mutually exclusive) attributes - salience, credibility, and legitimacy - and that what makes boundary crossing difficult is that actors on different sides of a boundary perceive and value salience, credibility, and legitimacy differently. Presenting research on water management regimes in the United States, international agricultural research systems, El Nino forecasting systems in the Pacific and southern Africa, and fisheries in the North Atlantic, this paper explores: 1) how effective boundary work involves creating salient, credible, and legitimate information simultaneously for multiple audiences; 2) the thresholds, complementarities and tradeoffs between salience, credibility, and legitimacy when crossing boundaries; and 3) propositions for institutional mechanisms in boundary organizations which effectively balance tradeoffs, take advantage on complementarities, and reach thresholds of salience, credibility, and legitimacy.
STATE OF THE ART FOETAL TESTOSTERONE – IMPLICATIONS IN AUTISM

Pervasive developmental disorders are a heterogeneous group of conditions believed to arise from combinations of genetic and environmental influences. The androgen theory of autism suggests that autism spectrum conditions (ASC) are in part due to elevated levels of foetal testosterone (fT). Prenatal testosterone has important effects on brain organization and future behavior and this is positively correlated with a number of autistic traits. In this article we emphasize on the importance of hormonal influence and the lasting effects on neuropsycho development. Given the crucial role of prenatal exposure to hormones in the development of cognitive sex differences and traits associated with ASC, for future directions we consider it is important to detail the latest information on androgen hormone levels during pregnancy.
Multiple effects of hydrogen peroxide and temperature on antioxidants and bleaching

This study reports the effect of simultaneous exposure to increased hydrogen peroxide (H2O2) levels and high seawater temperature on antioxidant enzyme (SOD and CAT) activities and bleaching in the coral Galaxea fascicularis. SOD activities in zooxanthellae were increased by H2O2 and a high temperature, but not by H2O2 alone. Thus, the increased SOD activity in zooxanthellae after exposure to a high temperature and H2O2 levels was caused solely by the high temperature. CAT activities were significantly increased by H2O2 and a high temperature in coral tissue and zooxanthellae. However, CAT activities were not increased by higher H2O2 levels at a high temperature. Coral and zooxanthellae have a limited capacity to increase their CAT activities. Decrease of zooxanthellae density was observed after exposure to increased H2O2 at a high temperature, but zooxanthellae densities were higher than those after exposure to a high temperature alone. Coral bleaching was inhibited by simultaneous exposure to H2O2 and a high temperature, despite an oxidative stress level known to damage coral metabolism. The zooxanthellae produced ROS under simultaneous H2O2 and high temperature stresses, as suggested by the increased SOD activities. It is likely that the system for trigger of bleaching was unable to act because of the high H2O2 concentration in the coral cytosol during H2O2 exposure, which led few concentration differences.
A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients: the INCAS Trial. Italy, The Netherlands, Canada and Australia Study.

CONTEXT Current guidelines recommend that individuals infected with the human immunodeficiency virus type 1 (HIV-1) be treated using combinations of antiretroviral agents to achieve sustained suppression of viral replication as measured by the plasma HIV-1 RNA assay, in the hopes of achieving prolonged remission of the disease. However, until recently, many drug combinations have not led to sustained suppression of HIV-1 RNA. OBJECTIVE To compare the virologic effects of various combinations of nevirapine, didanosine, and zidovudine. DESIGN Double-blind, controlled, randomized trial. SETTING University-affiliated ambulatory research clinics in Italy, the Netherlands, Canada and Australia (INCAS). PATIENTS Antiretroviral therapy-naive adults free of the acquired immunodeficiency syndrome with CD4 cell counts between 0.20 and 0.60x10(9)/L (200-600/microL). INTERVENTION Patients received zidovudine plus nevirapine (plus didanosine placebo), zidovudine plus didanosine (plus nevirapine placebo), or zidovudine plus didanosine plus nevirapine. MAIN OUTCOME MEASURE Plasma HIV-1 RNA. RESULTS Of the 153 enrolled patients, 151 were evaluable. At week 8, plasma HIV-1 RNA levels had decreased by log 2.18, 1.55, and 0.90 in the triple drug therapy, zidovudine plus didanosine, and zidovudine plus nevirapine groups, respectively (P<.05). The proportions of patients with plasma HIV-1 RNA levels below 20 copies per milliliter at week 52 were 51%, 12%, and 0% in the triple drug therapy, zidovudine plus didanosine, and zidovudine plus nevirapine groups, respectively (P<.001). Viral amplification was attempted in 59 patients at 6 months. Viral isolation was unsuccessful in 19 (79%) of 24, 10 (53%) of 19, and 5 (31%) of 16 patients in the triple drug therapy, zidovudine plus didanosine, and zidovudine plus nevirapine groups, respectively. Among patients from whom virus could be amplified, resistance to nevirapine was found in all 11 patients receiving zidovudine plus nevirapine and in all 5 patients receiving triple drug therapy. Rates of disease progression or death were 23% (11/47), 25% (13/53), and 12% (6/51) for the zidovudine plus nevirapine, zidovudine plus didanosine, and triple drug therapy groups, respectively (P=.08). CONCLUSIONS Triple drug therapy with zidovudine, didanosine, and nevirapine led to a substantially greater and sustained decrease in plasma viral load than the 2-drug regimens studied. Our results also suggest that suppression of viral replication, as demonstrated by a decrease in the plasma HIV-1 RNA load below the level of quantitation of the most sensitive test available, may at least forestall the development of resistance.
A HYBRID FILTER AND WRAPPER FEATURE SELECTION APPROACH FOR DETECTING CONTAMINATION IN DRINKING WATER MANAGEMENT SYSTEM

Feature selection is an important task in predictive models which helps to identify the irrelevant features in the high dimensional dataset. In this case of water contamination detection dataset, the standard wrapper algorithm alone cannot be applied because of the complexity. To overcome this computational complexity problem and making it lighter, filter-wrapper based algorithm has been proposed. In this work, reducing the feature space is a significant component of water contamination. The main findings are as follows: (1) The main goal is speeding up the feature selection process, so the proposed filter based feature pre-selection is applied and guarantees that useful data are improbable to be detached in the initial stage which discussed briefly in this paper. (2) The resulting features are again filtered by using the Genetic Algorithm coded with Support Vector Machine method, where it facilitates to nutshell the subset of features with high accuracy and decreases the expense. Experimental results show that the proposed methods trim down redundant features effectively and achieved better classification accuracy.
Determinants of Business Cycle Synchronization in East Asia: An Extreme Bound Analysis

We investigate the determinants of business cycle synchronization in East Asia by testing the robustness of the potential candidates, using the technique of Extreme Bound Analysis in an OLS regression framework with Newey-West correction for heteroskedasticity and autocorrelation. We find that trade openness and intra-industry trade are major channels of business cycle synchronization. Although the similarity of monetary policies is statistically correlated with degree synchronization, we are unsure whether the former causes the latter or vise versa. The findings are probably good news to the proponents of the prospective currency union. If the trend of increasing openness and bilateral intra-industry trade continues in East Asia, it is expected that the costs of forming a currency union would diminish as business cycles become more synchronized.
Antidiabetic and hepatoprotective activities of Tamarindus indica fruit pulp in alloxan induced diabetic rats

Background: Tamarindus indica belongs to family Caesalpiniaceae. Fruit pulp of Tamarindus indica is believed to have antidiabetic, hepatoprotective and many other medicinal properties. The objective of this study was to investigate antidiabetic, hypolipidemic and hepatoprotective activity of ethanolic extract of Tamarindus indica fruit pulp in alloxan induced diabetic rats. Materials and Methods: Animals were divided into 5 groups (n = 6). Normal and diabetic control groups received normal saline and alloxan (150 mg/kg body weight intraperitoneally) respectively. Animals were made diabetic by injection of single dose of alloxan in three test groups and after that they were treated with ethanolic extract of fruit pulp of Tamarindus indica 300 and 500 mg/kg/body weight orally and metformin 150 mg/kg body weight orally respectively for 14 days. Antidiabetic activity was estimated by measuring serum glucose and lipid profile; and hepatoprotective activity was measured by estimating serum liver enzyme levels and histopathological changes in liver tissues. Results were analyzed by One way ANOVA followed by Scheffe multiple comparison tests (p<0.01). Results: The two dose levels of Tamarindus indica significantly altered alloxan induced changes in serum glucose, lipid profile and serum enzyme levels. But in liver histopathology, higher dose (500 mg/kg) of plant showed complete regeneration whereas lower dose (300 mg/kg) showed only partial improvement in liver histopathology profile.
Oncological and Functional Outcomes of Laparoscopic Radiofrequency Ablation and Partial Nephrectomy for T1a Renal Masses: A Retrospective Single-center 60 Month Follow-up Cohort Study.

PURPOSE It remains unclear whether laparoscopic radiofrequency ablation (RFA) for primary treatment of small renal masses is similar to partial nephrectomy (PN) in terms of long-term oncological and renal function outcomes. We reviewed the long-term outcomes for patients with T1a renal masses treated with either laparoscopic RFA orPN. MATERIALS AND METHODS This retrospective single-center study on 115 patients who were treated by laparoscopic RFA or PN for small (<4 cm) renal masses between January 2005 and October 2014 at Chungnam National University Hospital. Estimated glomerular filtration rate (eGFR) was measured before and 1-2 weeks after surgery and at last follow-up. The laparoscopic RFA and PN groups were compared in terms of clinical characteristics data and change in eGFR after surgery using the Chi-squared test or Student's t-test. Survival data were analyzed using theKaplan-Meier method and the log-rank test. RESULTS Of the 115 patients, 62 and 53 underwent laparoscopic RFA and PN, respectively. Their mean (range) follow-up duration was 60 (30-104) and 68 (30-149) months, respectively (P = 0.092). The RFA patients were older (P = 0.023) and had smaller tumors (P = 0.000). RFA associated with shorter operation and hospitalization times and less perioperative blood loss (all P<0.001). The groups did not differ in terms of change in eGFR 1-2 weeks after surgery (P = 0.252) or at the last follow-up (P = 0.395) or 5 year survival rates (P = 0.360). CONCLUSION Laparoscopic RFA for small renal masses was comparable to PN in terms of oncological and functional outcomes and associated with shorter operative and hospitalization times and less perioperative bleeding.
Recommending collaborators using social features and MeSH terms

Unlike expertise location systems which users query actively when looking for an expert, expert recommender systems suggest individuals without the context of a specific problem. An interesting research question is whether expert recommender systems should consider a users' social context when recommending potential research collaborators. One may argue that it might be easier for scientists to collaborate with colleagues in their social network, because initiating collaboration with socially unconnected researchers is burdensome and fraught with risk, despite potentially relevant expertise. However, many scientists also initiate collaborations outside of their social network when they seek to work with individuals possessing relevant expertise or acknowledged experts. In this paper, we studied how well content-based, social and hybrid recommendation algorithms predicted co-author relationships among a random sample of 17,525 biomedical scientists. To generate recommendations, we used authors' research expertise inferred from publication metadata and their professional social networks derived from their co-authorship history. We used 80% of our data set (articles published before 2007) as our training set, and the remaining data as our test set (articles published in 2007 or later). Our results show that a hybrid algorithm combining expertise and social network information outperformed all other algorithms with regards to Top 10 and Top 20 recommendations. For the Top 2 and Top 5 recommendations, social network-based information alone generated the most useful recommendations. Our study provides evidence that integrating social network information in expert recommendations may outperform a purely expertise-based approach.