Miracle-dz/UniFAR-FTUs huggingface dataset:
Swing: Generating Realistic Background Packet Traces for Large-Scale Internet Topologies

One important question facing both network designers and distributed application developers is the interaction of the communication of a single network service or application with aggregate background traffic conditions. Unfortunately, network services are evaluated with typically no competing background traffic or, in the best case, ad hoc and simplistic traffic models. A related question is the effect that widely varying network traffic patterns have on network planning and resource allocation. For instance, the predicted growth of one application versus another (e.g., multimedia versus instant messaging) may have dramatically different impacts on a network’s traffic matrix. Yet, there is currently no way to quantify such effects. Thus, this paper proposes Swing, a flexible workload generator that accurately captures the packet interactions of a wide variety of applications based on a simple set of parameters. Our initial implementation includes settings for HTTP, P2P, and multimedia applications. We verify the accuracy of our application models by extracting application characteristics from available large-scale packet traces and by validating our generated traces against these same traces. We run Swing in ModelNet, a scalable and accurate network emulator to evaluate the interactions of distributed applications with a variety of traffic mixes. We show how to use these runs to measure dynamically changing router queue occupancy to “play back” realistic background traffic scenarios without actually generating any traffic. Finally, we use Swing to model the effect of traffic scenarios and topology on aggregate network load, for instance, as a network planning tool.
Recent trends in machine learning for human activity recognition—A survey

There has been an upsurge recently in investigating machine learning techniques for activity recognition (AR) problems as they have been very effective in extracting and learning knowledge from the activity datasets. The technique ranges from heuristically derived hand‐crafted feature‐based traditional machine learning algorithms to the recently developed hierarchically self‐evolving feature‐based deep learning algorithms. AR continues to remain a challenging problem in uncontrolled smart environments despite the amount of work contributed by the researcher in this field. The complex, volatile, and chaotic nature of the activity data presents numerous challenges that influence the performance of the AR systems in the wild. In this article, we present a comprehensive overview of recent machine learning and data mining techniques generally employed for AR and the underpinning problems and challenges associated with the existing systems. We also articulate the recent advances and state‐of‐the‐art techniques in this domain in an attempt to identify the possible directions for future AR research.
Blood-Based Lipidomics Approach to Evaluate Biomarkers Associated With Response to Olanzapine, Risperidone, and Quetiapine Treatment in Schizophrenia Patients

This is the first study to identify lipidomic markers in plasma associated with response of acutely ill schizophrenia patients in response to specific antipsychotic treatments. The study population included 54 schizophrenia patients treated with antipsychotics for 6 weeks. Treatment led to significant improvement in positive and negative symptoms for 34 patients with little or no improvement for 20 patients. In addition, 37 patients showed an increase in body mass index after the 6 week treatment period, consistent with effects on metabolism and the association of such effects with symptom improvement. Profiling of plasma samples taken prior to therapy using liquid chromatography tandem mass spectrometry (LC-MS/MS) resulted in identification of 38, 10, and 52 compounds associated with the olanzapine, risperidone, and quetiapine treatment groups, which could be used to distinguish responders from non-responders. Limitations include the retroactive active nature of the study and the small sample size. Further investigations with larger sample sets could lead to the development of a molecular test that could be used to help psychiatrists determine the best treatment options for each patient.
High-efficiency hybrid solar cells by nanostructural modification in PEDOT:PSS with co-solvent addition

Conducting polymer poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) is gaining technological importance for the fabrication of organic and organic–inorganic heterostructure devices. The conductivity of PEDOT:PSS can be improved by the addition of co-solvents. Here, we show that the simple addition of a suitable wt% of a co-solvent, either ethylene glycol (EG) or dimethyl sulfoxide (DMSO), in PEDOT:PSS can significantly enhance the performance of hybrid solar cells. We provide a morphological model to explain the influence of the co-solvents in PEDOT:PSS, in which the co-solvent modifies the internal crystalline ordering of individual PEDOT nanocrystals that increases the crystal size and forms closely packed nanocrystals, and it also facilitates rearrangement of PSS that reduces its surface chain networks to enhance the polymer conductivity and hybrid solar cell properties. A hybrid solar cell made of EG 7 wt% modified PEDOT:PSS on planar Si exhibits an exceptionally high power conversion efficiency exceeding 12% for the first time.
MiR-489-3 p inhibits cervical cancer cell migration and invasion through regulating Wnt / β-catenin signaling pathways

MicroRNAs (miRNAs) play crucial roles in the development and progression of human cancers, including cervical cancer. The discovery of miRNAs may provide a new and powerful tool for studying the mechanism, diagnosis, and treatment of cervical cancer. In this study, we aimed to investigate the role and mechanism of miR489-3p in the development and progression of cervical cancer. Quantitative real-time PCR (qRT-PCR) was used to measure the expression level of miR-489-3p in cervical cancer tissues and cell lines and found that miR-489-3p was significantly down-regulated. In addition, over-expression of miR-489-3p inhibited cervical cancer cell migration and invasion. Subsequent dual-luciferase reporter assay identified one of the proto-oncogene RAB1 as direct target of miR-489-3p, and RAB1 can save metastasis inhibition caused by miR-489-3p. We also confirmed that the metastasis inhibition caused by miR-489-3p is associated with Wnt/β-catenin pathway activation. Taken together, our results indicate that miR-489-3p could serve as a potential diagnostic biomarker and therapeutic option for cervical cancer in the near future.
Pitch accent type affects lexical activation in German : evidence from eye tracking

This visual world eye tracking study tests how f0 affects stress perception in online speech comprehension. The screen showed segmentally overlapping cohort pairs with different stress patterns (WSW/SWW) together with two distractors. In experimental trials, auditory stimuli referred to the WSW cohort member, which was presented with a medial-peak (L+H* L-%) or an early-peak pitch accent (H+L* L-%). Prior to segmental disambiguation, participants fixated the SWW stress competitor more when the WSW target was presented with an early-peak accent. Hence, the peak position affects lexical activation, such that pitch peaks preceding stressed syllables in WSW words temporarily activate SWW words.
Increasing data rates in relay-assisted wireless multicast networks with single antenna receivers

In this paper, we exploit cooperation between mobile stations and transmissions scheduling in a wireless multicast network to enhance the data rates to multiple single antenna users. The objective is to increase the number of multiplexed signals within a channel use. Specifically, we divide the communication process into two stages. In the first stage, the base station (BS) with multiple antennas using time division multiplexing transmits to different multicast groups in their allocated time slots. The number of messages sent in one time slot is equal to the number of transmit antennas at the BS. In the next stage, the multicast group of "co-located" users and its assigned relays form an independent network, where amplify-and-forward relays aid the recovery of the BS messages, with the users solving a linear system of equations at the end of this stage. All of these subnetworks utilize the available channel concurrently producing an acceptable level of multiple access interference (MAI) where the MAI is controlled using a clustering technique tailored to the location of multicast groups. Simulation results are provided demonstrating the capacity improvements in the proposed scheme.
Ultrastructural Analysis and ABR Alterations in the Cochlear Hair-cells Following Aminoglycosides Administration in Guinea Pig

Aims: Aminoglycosides (AG) antibiotics were the first ototoxic agents to highlight the problem of drug-induced hearing and vestibular loss, since their introduction in the 1940. The aim of the present work was to characterize ultrastructural alterations of the sensory hair-cell following different aminoglycosides administration, intratympanic VS intraperitoneal and to correlate them with auditory brainstem responses (ABR). Methods: A total of 48 adult guinea pigs were divided into 8 groups; six animals in each group. The first four groups received saline (control), streptomycin, gentamycin, or netilmicin; respectively, via the peritoneal route. The next four groups received similar treatment via transtympanic route. The treatment was administered for seven consecutive days. On day 10, ABR was utilized for hearing evaluation and scanning electron microscopy (SEM) examination of the sensory organs was used for morphological study. Results: Streptomycin produced the most severe morphological changes and a higher elevation of ABR thresholds, followed, in order, by gentamycin and netilmicin. Netilmicin ototoxicity observed in both systemic and transtympanic routes was low because of lesser penetration into the inner ear or/ and lower intrinsic toxicity. Conclusion: Streptomycin cochleotoxicity lesion involves destruction of the sensory hair cells of the cochlear epithelium which was quantified functionally and ultrastructurally. Streptomycin was the most cochleotoxic among the AG administrated, followed by gentamycin and netilmicin. Moreover, we demonstrated the presence of surface scavenger microphages in close association with auditory hair cells in the normal physiological conditions. Such cells may form part of the resident immune surveillance of organ of Corti.
Arabic Romanization System CARS

The CJKI Arabic Romanization System, or CARS, is an innovative phonemic transcription system developed mainly for ease of use by learners and as an aid to linguists in analyzing the phonological structure of Modern Standard Arabic (MSA). The most important feature of CARS is its readability: its unambiguous encoding of phonological and prosodic information in an intuitive, easy to read set of symbols. The new system, which is making its debut with the appearance of The CJKI Arabic Learner’s Dictionary, has several unique features not found elsewhere, including a symbol set that represents all Arabic phonemes unambiguously, and, for the first time, symbols indicating word stress and vowel neutralization. This paper describes how CARS is used to represent phonemic, prosodic, syllabic, grammatical and some phonetic information in a user-friendly manner.
Five-Year Suicidal Ideation Trajectories Among Women Receiving or Being Denied an Abortion.

OBJECTIVE The aim of this study was to assess the effects of receiving compared with being denied an abortion on women's experiences of suicidal ideation over 5 years. METHOD The authors recruited 956 women from 30 U.S. abortion facilities. Women were interviewed by telephone 1 week after their abortion visit, then every 6 months for 5 years. Women who received near-limit abortions were compared with women who were denied an abortion and carried their pregnancies to term (turnaway-birth group). Women completed the suicidal ideation items on the Brief Symptom Interview (BSI) and the Patient Health Questionnaire (PHQ-9). The Sheehan Suicidality Tracking Scale was used to assess imminent suicidality. Adjusted mixed-effects regression analyses accounting for clustering by site and individual were used to assess whether levels and trajectories of suicidality differed by group. RESULTS One week after abortion seeking, 1.9% of the near-limit group and 1.3% of the turnaway-birth group reported any suicidal ideation symptoms on the BSI. Over the 5-year study period, the proportion of women with any suicidal ideation symptoms on the BSI declined significantly to 0.25% for women in the near-limit group and nonsignificantly to 0.21% for those in the turnaway-birth group. In four out of 7,247 observations (0.06%), women reported being imminently suicidal. There was no statistically significant differential loss to follow-up by baseline report of suicidal ideation or history of depression or anxiety. There were no statistically significant group differences on any suicidal ideation outcome over the 5-year study period. CONCLUSIONS Levels of suicidal ideation were similarly low between women who had abortions and women who were denied abortions. Policies requiring that women be warned that they are at increased risk of becoming suicidal if they choose abortion are not evidence based.
Learning another ’ s preference to punish increases one ’ s own punitive behavior

Methods Explanation of each option in the Justice Game. According to the theory of retributive justice, an appropriate response to a fairness violation is to ensure that punishment is proportionate to the crime committed. Retributive justice can be dated back through recorded history, and is enshrined within most modern legal systems. These philosophies are formalized in psychological theory: if the punishment fits the crime, a person is deservingly punished proportionate to the moral wrong committed, often referred to as a ‘just deserts’ or deservingness principle (Carlsmith et al. 2002). In order to operationalize this in our task, we reasoned that reversing the Players’ outcomes allows for the maximum punishment to be applied to Player A while also giving the maximum compensation to Player B. Moreover, reversing the Players’ payouts results in Player A receiving what was initially assigned for Player B, and vice versa—a direct implementation of the ‘just deserts’ principle.
DESIGN AND VALIDATION OF ACCELERATION MEASUREMENT USING THE MARTLET WIRELESS SENSING SYSTEM

The adoption of wireless sensing technology by the structural health monitoring community has shown advantages over traditional cable-based systems, such as convenient sensor installation and lower system cost in many applications. Recently, a new generation of wireless sensing platform, named Martlet, has been collaboratively developed by researchers at the University of Michigan, Georgia Tech, and Michigan Tech. Martlet adopts a Texas Instruments Piccolo microcontroller running up to 90 MHz clock frequency, which enables Martlet to support high-frequency data acquisition and high-speed onboard computation. The extensible design of the Martlet printed circuit boards allows convenient incorporation of various sensor boards. In order to obtain accurate acceleration data and meanwhile reduce the sensor cost, a new Martlet sensor board, named integrated accelerometer wing, is developed. The integrated accelerometer wing adopts a commercial-off-the-shelf MEMS (microelectromechanical systems) accelerometer and contains an onboard signal conditioner performing three basic functions, including mean shifting, anti-aliasing filtering and signal amplification. One distinct feature of the signal conditioner is the on-the-fly programmable cut-off frequency and amplification gain factor. To validate the performance of Martlet and the integrated accelerometer wing, experiments are carried out on a laboratory four-story aluminum shear-frame structure. The laboratory experiment results demonstrate that the performance of the wireless sensing system is comparable to that of cabled reference sensors. In addition, using data collected by wireless sensors, vibration modal properties of the structure are identified and finite element (FE) model updating is performed. © 2014 ASME
Identifying Global and Culture-Specific Dimensions of Humor in Advertising: A Multinational Analysis

Humor is a commonly used communication tool in advertising in the United States, but U.S. marketers know little about its use and effectiveness in foreign markets. Such limited knowledge hinders international managers’ ability to determine which aspects of humorous communications are likely to be amenable to global standardization and which should be adapted to local expectations. The authors examine the content of humorous television advertising from four national cultures: Korea, Germany, Thailand, and the United States. Findings indicate that humorous communications from such diverse national cultures share certain universal cognitive structures underlying the message. However, the specific content of humorous advertising is likely to be variable across national cultures along major normative dimensions such as collectivism-individualism.
Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines

Advancing biologically driven soft robotics and actuators will involve employing different scaffold geometries and cellular constructs to enable a controllable emergence for increased production of force. By using hydrogel scaffolds and muscle tissue, soft biological robotic actuators that are capable of motility have been successfully engineered with varying morphologies. Having the flexibility of altering geometry while ensuring tissue viability can enable advancing functional output from these machines through the implementation of new construction concepts and fabrication approaches. This study reports a forward engineering approach to computationally design the next generation of biological machines via direct numerical simulations. This was subsequently followed by fabrication and characterization of high force producing biological machines. These biological machines show millinewton forces capable of driving locomotion at speeds above 0.5 mm s−1. It is important to note that these results are predicted by computational simulations, ultimately showing excellent agreement of the predictive models and experimental results, further providing the ability to forward design future generations of these biological machines. This study aims to develop the building blocks and modular technologies capable of scaling force and complexity of these devices for applications toward solving real world problems in medicine, environment, and manufacturing.
Digital breast tomosynthesis: a concise overview

The proven limited sensitivity of mammography, due to tissue superposition in a 2D image, has motivated the development of alternative 3D imaging systems with minimal ionizing exposure and relatively low cost. The advent of digital detectors facilitated the realization of digital breast tomosynthesis systems, which acquire low-dose projection images of the breast from multiple directions to synthesize slices through the volume of the breast parallel to the plane of the projection images. Although still in its clinical infancy, this imaging system has been studied in a multitude of domains. This concise overview introduces digital breast tomosynthesis and elaborates on the state-of-the-art in its applications and performance.
Targeted Killing of Streptococcus mutans in Biofilms by a Pheromone Guided Antimicrobial Peptide HP30

Targeted Killing of Streptococcus mutans in Biofilms by a Pheromone Guided Antimicrobial Peptide HP30 Tian XL1, Chen C1, Cyr K1, Dong G1, Salim H2 and Li YH*1,2 1Department of Applied Oral Sciences, Dalhousie University, Halifax, NS, Canada 2Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada *Corresponding author: Li YH, Department of Microbiology and Immunology, 5981 University Ave. Rm5215 Halifax, Nova Scotia, Canada, B3H 1W2, Fax: 1-902-494-6621, Tel: 1-902-494-3063, E-mail: yunghua.li@dal.ca Citation: Tian XL, Chen C, Cyr K, Dong G, Salim H, et al. (2017) Targeted Killing of Streptococcus mutans in Biofilms by A Pheromone-Guided Antimicrobial Peptide HP30. J Antibio Res 1(2): 201
Helicobacter pylori genetic diversification in the Mongolian gerbil model

Helicobacter pylori requires genetic agility to infect new hosts and establish long-term colonization of changing gastric environments. In this study, we analyzed H. pylori genetic adaptation in the Mongolian gerbil model. This model is of particular interest because H. pylori-infected gerbils develop a high level of gastric inflammation and often develop gastric adenocarcinoma or gastric ulceration. We analyzed the whole genome sequences of H. pylori strains cultured from experimentally infected gerbils, in comparison to the genome sequence of the input strain. The mean annualized single nucleotide polymorphism (SNP) rate per site was 1.5e−5, which is similar to the rates detected previously in H. pylori-infected humans. Many of the mutations occurred within or upstream of genes associated with iron-related functions (fur, tonB1, fecA2, fecA3, and frpB3) or encoding outer membrane proteins (alpA, oipA, fecA2, fecA3, frpB3 and cagY). Most of the SNPs within coding regions (86%) were non-synonymous mutations. Several deletion or insertion mutations led to disruption of open reading frames, suggesting that the corresponding gene products are not required or are deleterious during chronic H. pylori colonization of the gerbil stomach. Five variants (three SNPs and two deletions) were detected in isolates from multiple animals, which suggests that these mutations conferred a selective advantage. One of the mutations (FurR88H) detected in isolates from multiple animals was previously shown to confer increased resistance to oxidative stress, and we now show that this SNP also confers a survival advantage when H. pylori is co-cultured with neutrophils. Collectively, these analyses allow the identification of mutations that are positively selected during H. pylori colonization of the gerbil model.
APLICAÇÃO DE MÉTODOS GEOELÉTRICOS PARA MONITORAMENTO DA BARRAGEM DE CONCRETO DA UHE GOV. JOSÉ RICHA

A utilizacao dos ensaios geofisicos no macico da barragem da Usina Hidreletrica Governador Jose Richa (Salto Caxias) teve como objetivo principal desenvolver metodologia complementar ao sistema de monitoramento hoje existente. Mais especificamente, o metodo SP (“self potential”) foi usado com o objetivo de mapear os caminhos preferenciais da agua, enquanto que os ensaios de resistividade tiveram um papel complementar, fornecendo informacao sobre o grau de saturacao (conteudo em agua) no corpo da barragem. O arranjo gradiente, pela maior praticidade que apresenta, foi o escolhido como arranjo eletrodico mais adequado para mapeamento de variacoes laterais de resistividade em tal meio de alta resistencia de contato concreto-eletrodos.