Miracle-dz/UniFAR-FTUs huggingface dataset:
Improving Lower Limb Weight Distribution Asymmetry During the Squat Using Nintendo Wii Balance Boards and Real-Time Feedback

McGough, R, Paterson, K, Bradshaw, EJ, Bryant, AL, and Clark, RA. Improving lower limb weight distribution asymmetry during the squat using Nintendo WII balance boards and real-time feedback. J Strength Cond Res 26(1): 47–52, 2012—Weight-bearing asymmetry (WBA) may be detrimental to performance and could increase the risk of injury; however, detecting and reducing it is difficult in a field setting. This study assessed whether a portable and simple-to-use system designed with multiple Nintendo Wii Balance Boards (NWBBs) and customized software can be used to evaluate and improve WBA. Fifteen elite Australian Rules Footballers and 32 age-matched, untrained participants were tested for measures of WBA while squatting. The NWBB and customized software provided real-time visual feedback of WBA during half of the trials. Outcome measures included the mean mass difference (MMD) between limbs, interlimb symmetry index (SI), and percentage of time spent favoring a single limb (TFSL). Significant reductions in MMD (p = 0.028) and SI (p = 0.007) with visual feedback were observed for the entire group data. Subgroup analysis revealed significant reductions in MMD (p = 0.047) and SI (p = 0.026) with visual feedback in the untrained sample; however, the reductions in the trained sample were nonsignificant. The trained group showed significantly less WBA for TFSL under both visual conditions (no feedback: p = 0.015, feedback: p = 0.017). Correlation analysis revealed that participants with high levels of WBA had the greatest response to feedback (p < 0.001, ρ = 0.557). In conclusion, WBA exists in healthy untrained adults, and these asymmetries can be reduced using real-time visual feedback provided by an NWBB-based system. Healthy, well-trained professional athletes do not possess the same magnitude of WBA. Inexpensive, portable, and widely available gaming technology may be used to evaluate and improve WBA in clinical and sporting settings.
A path unenvisaged to a destination unintended : a collaborative autoethnographic account of becoming a community of practice in an HEI

In this paper we explore how a disparate group of predominately foundation phase teacher educators unintentionally, over a period of time, came together to form a strong community of practice (CoP). Voluntary involvement in a research project positioned this group of lecturers in unaccustomed roles and necessitated that they engage with each other in a variety of ways to meet project outcomes. New relationships developed as people took on different roles and new responsibilities emerged as the group faced challenges. As this was a subjective interrogation of our experiences, a research method such as autoethnography where we could focus on the experience and processes of becoming a CoP, rather than the outcomes of the research itself, seemed appropriate. We outline our understandings of a CoP and show how, through a critical self-reflective process, we were able to strengthen both our teaching and research practices in a Higher Education Institution (HEI). The strengthening occurred, in part, due to the formation and development of this CoP.
Securing with algorithms: Knowledge, decision, sovereignty

Amid the deployment of algorithmic techniques for security – from the gathering of intelligence data to the proliferation of smart borders and predictive policing – what are the political and ethical stakes involved in securing with algorithms? Taking seriously the generative and world-making capacities of contemporary algorithms, this special issue draws attention to the embodied actions of algorithms as they extend cognition, agency and responsibility beyond the conventional sites of the human, the state and sovereignty. Though focusing on different modes of algorithmic security, each of the contributions to the special issue shares a concern with what it means to claim security on the terrain of incalculable and uncertain futures. To secure with algorithms is to reorient the embodied relation to uncertainty, so that human and non-human cognitive beings experimentally generate and learn what to bring to the surface of attention for a security action.
Raman study of the CeO2 texture as buffer layer in the CeO2/La2Zr2O7/Ni architecture for coated conductors

CeO 2 /La 2 Zr 2 O 7 /Ni piled-up structure is a very promising architecture for YBa 2 Cu 3 O 7 (YBCO) coated conductors. We have grown YBCO/CeO 2 / LZO/Ni epitaxial structures by metalorganic decomposition (MOD) and metalorganic chemical vapour deposition (MOCVD) methods. The crystallographic quality of the CeO 2 layer is not well determined by conventional X-Ray Diffraction (XRD) due to the superposition of LZO and CeO 2 reflections. An alternative simple Raman spectroscopy analysis of crystalline quality of the CeO 2 films is proposed. The F 2g Raman mode of CeO 2 can be quantified either by using two polarization configurations (crossed or parallel) or at two different rotation angles around the normal axis (0° and 45°) to obtain information about the sample texture. The sample texture can be determined via a quality factor (referred as Raman Intensity Ratio, RIR) consisting in calculating the ratio of the integrated intensity of the CeO 2 F 2g mode at 0° and 45° in parallel polarization. This factor correlates with superconducting performance and can be used as an on-line non destructive method.
pH Impedance and high‐resolution manometry in laryngopharyngeal reflux disease high‐dose proton pump inhibitor failures

Laryngopharyngeal reflux disease (LPRD) patients often fail empiric treatment with high‐dose, twice‐daily (BID) proton pump inhibitors (PPIs). Further testing is warranted to rule in or out nonacid reflux (NAR) or breakthrough acid reflux (BAR) as the etiology of the symptoms. Results of coordinated multichannel intraluminal pH impedance (MII) and high‐resolution esophageal manometry (HRM) testing while patients are on high‐dose BID PPIs is lacking in the LPRD population. The objective of this study is to evaluate if coordinated MII and HRM aid in the management of patients with persistent LPRD symptoms despite high dose BID PPIs.
Influence of selected factors on the volume of consumption (per capita) of Uruguay - in the sense of Granger causality

The project will be tested State Uruguay. The country is characterized by political stability, economic attractiveness of tax-free zones for investors, and also has a good infrastructure, communication network, as well as one of the best education systems in their continent. The aim of the study is to verify whether the selected factors affect the volume of consumption (per unit) in Uruguay. Selected factors are investment (per capita), imports (per capita), exports (per capita), government spending (per capita) and the level of consumer prices. Individual data are annual data, and analysis period in the years 1950-2009. Audit of Granger causality indicates that the inclusion of the individual regression equations delayed variables can better explain and predict the evolution of the size of consumption in Uruguay.
Inventory Allocation in the Presence of Service‐Level Agreements

Retailers often use service‐level agreements (SLAs) to evaluate their supplier's performance. Based on an examination of 70 SLAs from practice, we conclude that in terms of evaluating fill rate, these SLAs vary in at least three key dimensions: (i) Supplier performance can be evaluated for each demand request or over some longer horizon, (ii) the acceptable fill rate can be 100% or something less than 100%, and (iii) the non‐compliance charge can be a flat fee, a per‐unit‐short fee, or both. For a supplier operating a periodic‐review inventory system and serving multiple retailers, each with an SLA, we investigate the impact of inventory allocation rules on SLA compliance and expected non‐compliance costs across the three dimensions of review horizon, fill rate target and non‐compliance cost structure. We derive several analytic results when retailers are symmetric. For the single‐period setting and a fill rate target of 100%, we characterize the optimal allocation rule and rank other rules common in practice and the literature. We also characterize the optimal rule for the single‐period setting when the fill rate target is less than 100% and the SLA specifies a flat‐fee non‐compliance charge. In the multiple‐period case, we characterize the optimal rule when the fill rate target is 100%. When the fill rate target is less than 100% and the performance review horizon is more than one period, we develop a simple heuristic that outperforms common allocation rules.
Rapid online language mapping with electrocorticography.

OBJECT Emerging research in evoked broadband electrocorticographic (ECoG) measurement from the cortical surface suggests that it might cleanly delineate the functional organization of cortex. The authors sought to demonstrate whether this could be done in a same-session, online manner to identify receptive and expressive language areas. METHODS The authors assessed the efficacy of simple integration of "χ-band" (76-200 Hz) change in the ECoG signal by implementing a simple band-pass filter to estimate broadband spectral change. Following a brief (less than 10-second) period to characterize baseline activity, χ-band activity was integrated while 7 epileptic patients with implanted ECoG electrodes performed a verb-generation task. RESULTS While the patients were performing verb-generation or noun-reading tasks, cortical activation was consistently identified in primary mouth motor area, superior temporal gyrus, and Broca and Wernicke association areas. Maps were robust after a mean time of 47 seconds (using an "activation overlap" measure). Correlation with electrocortical stimulation was not complete and was stronger for noun reading than verb generation. CONCLUSIONS Broadband ECoG changes can be captured online to identify eloquent cortex. This demonstrates the existence of a powerful new tool for functional mapping in the operative and chronic implant setting.
Relationship between the limited and wide host range octopine-type Ti plasmids of Agrobacterium tumefaciens

The relationship between the limited host range octopine Ti plasmids and the wide host range octopine Ti plasmids pTiB6806 and pTiA6 was studied. The limited host range Ti plasmids shared extensive deoxyribonucleic acid homology; pTiAg63 and pTiAg162 were essentially completely homologous with pTiAg158 while pTiAg57 shared approximately 64% homology with pTiAg158. In contrast, the limited host range octopine Ti plasmids only shared 6 to 15% homology with the wide host range octopine Ti plasmid pTiB6806. Thus, limited and wide host range octopine Ti plasmids comprise distinct families of plasmids. The deoxyribonucleic acid homology shared between the limited host range Ti plasmids and pTiB6806, however, was distributed over some 50% of pTiB6806, suggesting that both families of plasmids evolved from a common progenitor plasmid. The limited host range Ti plasmids showed relatively strong homology with pTiB6806 HpaI fragment 7, a region which codes for octopine utilization by the bacterium, but showed only weak homology with pTiB6806 HpaI fragment 12, a region required for virulence. In addition, homology between the limited host range octopine Ti plasmids and the "common deoxyribonucleic acid," sequences shown to have a central role in plant cell transformation, was barely detectable when stringent hybridization conditions were used. We therefore conclude that a highly conserved version of the common deoxyribonucleic acid is not required for crown gall tumorigenesis on all plant species.
Updating the Accounts: Global Mortality of the 1918-1920 "Spanish" Influenza Pandemic

The influenza pandemic of 1918-20 is recognized as having generally taken place in three waves, starting in the northern spring and summer of 1918. This pattern of three waves, however, was not universal: in some locations influenza seems to have persisted into or returned in 1920. The recorded statistics of influenza morbidity and mortality are likely to be a significant understatement. Limitations of these data can include nonregistration, missing records, misdiagnosis, and nonmedical certification, and may also vary greatly between locations. Further research has seen the consistent upward revision of the estimated global mortality of the pandemic, which a 1920s calculation put in the vicinity of 21.5 million. A 1991 paper revised the mortality as being in the range 24.7-39.3 million. This paper suggests that it was of the order of 50 million. However, it must be acknowledged that even this vast figure may be substantially lower than the real toll, perhaps as much as 100 percent understated.
Two cases with interstitial deletions of chromosome 2 and sex reversal in one.

We present two children with de novo interstitial deletions of the long arm of chromosome 2 (karyotypes 46,XY, del(2)(q31.1q31.3) and 46,XY, del(2)(q24.3q31.3), respectively). The first child had severe learning difficulties, growth retardation, unilateral ptosis, small palpebral fissures, a cleft uvula, and bilateral cutaneous syndactyly of the second and third toes. Despite her male karyotype, she had female external genitalia with hypoplasia of the clitoris and labia minora. This is the first reported case of feminization of the external genitalia in a genotypic male with an interstitial deletion of chromosome 2q31 and adds to the growing amount of evidence for a gene involved in sex determination in this chromosome region. The second child had severe mental and growth retardation, ptosis, down-slanting palpebral fissures, low-set ears, micrognathia, finger camptodactyly, and brachysyndactyly of the second to fifth toes. The clinical manifestations associated with deletions of 2q31 to 2q33 are similar to those found with proximal deletions at 2q24 to 2q31 and of band 2q24, suggesting that the phenotype may result from haploinsufficiency for one or more genes located at 2q31. Microsatellite marker studies showed that both children had paternally derived deletions that included the HOXD gene cluster and the EVX2, DLX1, and DLX2 genes known to be important in limb development.
Valued Education For A Good Society And A Better Life

In initial and continuous training of teachers, requirements growing are about the need of integrate new technologies in education, to enhance interactive learning using strategies collaborative learning and assessment that constitutes the imperative of development of a society and a modern education and postmodern. This does not mean total abandonment of the traditional strategies, but blending effective with those that require a deeper involvement in the student's own training and development. This is due to the evolution of digital society, the emergence of new areas of knowledge and new individual and social needs of adapting to the flow of information which are in a constant effervescence. Teachers must learn how to motivate students to go through learning experiences proposed to apply the acquired acquisitions in new situations, building their new knowledge. If learning is a constructive process, then teacher training should be so designed to create opportunities for this construction. The education made with love is the highest form of training. © 2017 Published by Future Academy www.FutureAcademy. org.uk
Acceptance of Intimate Partner Violence in Rural Malawi: An Empirical Analysis on the Impacts of Lineage and AIDS Conversation Networks

Acceptance of intimate partner violence (IPV) is both a barrier to its reduction and a strong predictor of prevalence. This study examines whether lineage and AIDS conversation networks impact acceptance of IPV among men and women in rural Malawi. The sample consists of 4,422 male and female respondents from the 2001, 2004, and 2006 waves of the Malawi Longitudinal Study of Families and Health (MLSFH). The longitudinal nature of the data enables us to use not only random effects models in the empirical analysis, but also fixed effects models, which help alleviate omitted variable bias. Our findings suggest that in the patrilineal Northern Region of Malawi, AIDS conversation networks may be conducive toward reducing acceptance of IPV. However, AIDS conversation networks may reinforce violent norms in the Central Region of Malawi as men with larger AIDS conversation networks are more accepting of IPV. These findings imply there may be an opportunity to incorporate network-based policies to reduce IPV, and lineage may be an important consideration in forming policies to alleviate IPV. In addition, we find a relatively strong age-acceptance gradient, with younger, never-married individuals being less accepting of IPV than older, married individuals. This finding may help inform intervention targeting as older, married women in Malawi may be at a higher risk of IPV.
FREQUENCY OF APICAL AND LAMINAL / S / Frequency of Apical and Laminal / s / in Normal and Post-glossectomy Patients

Maureen Stone, Department of Neural and Pain Sciences; Orthodontics, University of Maryland School of Dentistry Susan Rizk, Department of Neural and Pain Sciences; Orthodontics, University of Maryland School of Dentistry Jonghye Woo, Department of Neural and Pain Sciences; Orthodontics, University of Maryland School of Dentistry Emi Z. Murano, Johns Hopkins University School of Medicine, O-HNS Hegang Chen, University of Maryland School of Medicine, Epidemiology Jerry L. Prince, Department of Electrical and Computer Engineering, Johns Hopkins University
Complete inhibition of the renin–angiotensin–aldosterone system; where do we stand?

Purpose of reviewThis review presents the role of combination therapy of renin–angiotensin–aldosterone system blockade on cardiovascular and kidney disease. Recent findingsThree large randomized controlled trials comparing combination therapy of renin–angiotensin–aldosterone system blockade to monotherapy in individuals with increased cardiovascular risk, chronic kidney disease, or diabetic nephropathy have been reported. These trials – ONTARGET, ALTITUDE, and VA NEPHRON-D – demonstrated an excess risk of adverse effects [especially acute kidney injury (AKI) and hyperkalemia] with combination therapy, without significant benefit in reducing cardiovascular and renal morbidity. SummaryCurrent evidence supports avoiding dual renin–angiotensin–aldosterone system blockade in patients with chronic kidney disease. Subsequent studies of dual renin–angiotensin–aldosterone system blockade should examine adverse event risks and renal progression endpoints.
Success and decline: top 10 tennis players follow a biphasic course.

INTRODUCTION The victory percentages for tennis players who entered the top 10 women and men rankings show various evolutions related to age and time since 1968. METHODS The study analyzed the careers of all top 10 players: 97 women (50,933 matches) and 144 men (92,450 matches). For each player, we describe a biphasic performance course. Two generations were compared: the first one (G1), including players who started their professional career before 1985, and the second one (G2), with players starting after 1985. RESULTS The average career length is 16.1 ± 3.8 yr for the top 10 men and 15.8 ± 4.4 yr for women. Compared with G1 players, G2 players begin earlier (women = 1.3 yr, men = 0.8 yr), but career length remains the same. An exponential model describes the time course of the victory percentage with a great similarity for both genders. Using this equation, the peak victory rate reaches 82.5% at 21.5 yr for number 1 (no. 1) women and 78.5% at 23.7 yr for no. 1 men, showing a greater precocity and earlier decline in women. Finally, the area under the curve shows a potential that is 22.8% (men) to 56.8% (women) larger for the no. 1 players as compared with all other numbers 2-10. CONCLUSIONS Tennis players in the top 10 show a biphasic career. Women reach their highest level earlier than men, consistent with their more precocious biological development. For the current generation, the peak performance tends toward a younger age than the first generation. We show how to precisely quantify and compare tennis performances using indicators that follow the trends of development and aging and demonstrate that precocity does not provide a larger victory potential.
High Circulating Leptin Receptors with Normal Leptin Sensitivity in Liver-specific Insulin Receptor Knock-out (LIRKO) Mice*

Liver-specific insulin receptor knock-out (LIRKO) mice display hyperinsulinemia, abnormal glucose metabolism, and progressive liver dysfunction. In addition, circulating leptin levels appear to be increased more than 10-fold. However, food intake, body weight, and adipose mass are not significantly altered in LIRKO mice compared with wild-type littermates. Using a ligand immunofunctional assay, we found that the apparent increase in circulating leptin in LIRKO mice is because of an 80-fold increased serum level of soluble leptin receptor. Gene expression analysis by microarray and real time PCR reveals the liver as the source of soluble leptin receptor in LIRKO mice, with an increase in expression of the short (Ob-Ra), long (Ob-Rb), and soluble (Ob-Re) forms of the leptin receptor. Direct control of leptin receptor expression by insulin could also be demonstrated in isolated hepatocytes from normal mice. Despite the markedly increased levels of leptin receptor in their circulation, LIRKO mice exhibit normal or even enhanced leptin sensitivity, as assessed by their physiological and molecular responses to exogenous leptin administration and their lower base-line hypothalamic levels of SOCS3 mRNA. Thus, insulin signaling in the liver plays an important role in control of leptin receptor expression and shedding. In the LIRKO mouse, this is lost, leading to markedly increased leptin receptors into the circulation. These high levels of circulating leptin receptor bind leptin and likely alter its clearance, but do not inhibit leptin action and may actually potentiate leptin action. In this manner, insulin signaling in liver plays an important role in leptin homeostasis and fine modulation of leptin action.
On the Design Methodology of Flexure-Based Compliant Mechanisms by Utilizing Pseudo-Rigid-Body Models with 3-DOF Joints

This paper focuses on the complex design process of planar compliant mechanisms with flexure hinges. In the following a systematic methodology of the transition from lever mechanisms generated intuitively by the developer or non-intuitively by topology optimization to applicable compliant mechanism is presented. An extended pseudo-rigid-body model (PRBM) is used for the analysis and the modification of the lever mechanisms during the design process. Hereby, the flexure hinges are assumed as planar joints with 3 degrees of freedom (DOF) and the corresponding stiffness/compliance. Therefore, the planar deformation of the flexure hinges caused by the applied force and moments can be displayed. Based on this extended PRBM a subsequent optimization for the mechanism and the flexure hinges is applied to significantly reduce time and effort of the development process. Based on the presented development methodology a novel compliant mechanism with one DOF is created. Here, a maximum displacement of 635. 8μm for an input displacement of 40μm can be achieved.