Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence of Congenital Anomalies of Uterus in Sohag Government: A Descriptive Study by Trans-Vaginal Three Dimensional Ultrasound

AbstractBackground: A large number of uterine anomalies are detected routinely in reproductive medicine. The prevalence of these congenital uterine anomalies in women with repro-ductive failure remains unclear especially in Upper Egypt.The Aim of Study: Was to estimate the prevalence of congenital uterine anomalies in women with infertility in Sohag by Transvaginal Three Dimensional Ultrasound (TV3DUS). Methods: This study was a descriptive cross-sectional study carried out for 977 infertile women in 2018 based on reviewing of radiological images at Sohag governorate. After taking informed and written consent, a detailed history, general and systemic examination was done. All the cases underwent TV3DUS performed during the postmenstrual phase. Exami-nations had been performed using flips iu220 machine by a single operator and was commented as either normal or abnormal uterine cavity.Results: A total of 977 women were included in the study. 808 (82.7%) had a normal uterus and 169 (17.3%) had a congenital uterine anomalies. The most common anomalies were arcuate [n=84 (49.7%)] and septate [n=62 (36.8%)] uterus, followed by unicornate [n=9 (5.3%)] and then T-shaped and hypoplastic uterus [n=4 each (2.3% each)], lastly didelphys and bicornate [n=3 each (1.8% each)]. Conclusions: TV3D ultrasound is an accurate and simple method to detect and classify congenital uterine anomalies and should become the first diagnostic step in the assessment of the uterine cavity. Prevalence of uterine congenital anomalies in Sohag was 17.3%. The most common type of uterine congenital anomalies was arcuate uterus.
Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding

A dynamic/friction brake blending valve device having a piston assembly arranged to operate a pressure regulator via which brake cylinder pressure is controlled. Associated with the relay valve device is an electrical circuit comprising a differential amplifier subject in a first mode of operation to a brake command signal and a dynamic brake signal representing the degree of dynamic brake effort being provided in response to the brake command. An error signal resulting from comparison of the brake command and dynamic brake signals is converted by a transducer to a corresponding fluid pressure that is supplied to a chamber formed between first and second differential pistons of the piston assembly to actuate the pressure regulator and thereby produce brake cylinder pressure corresponding to the deficiency of the dynamic brake. Another chamber formed between the second piston and a third differential piston of the piston assembly may be connected to a pneumatic control valve device that operates in response to brake pipe pressure variations, which may be made independently of the brake command signal, to provide apparatus for obtaining a back-up or emergency brake application in the event an electrical malfunction renders the differential amplifier inoperative. In a second mode of operation, the differential amplifier error signal is replaced by the dynamic brake signal and the brake pipe pressure is adjusted simultaneously with the brake command so as to correspond thereto. In this respect, the brake blending valve device itself accomplishes the comparison function provided by the differential amplifier in the first mode of operation, in order to supplement the dynamic brake with friction brake effort corresponding to any deficiency of the dynamic brake which may arise.
ORGANIC COMPOUNDS IN ROAD DUST AND THEIR ASSOCIATION WITH TRAFFIC

Settled road dust was examined to detect the presence of organic compounds. Samples were collected from a road surface near a busy road junction in the city of Ostrava, Czech Republic, once a month from May to October. The six collected samples were analyzed by gas chromatography with mass detection. The correlation analysis divided the analyzed compounds into three distinct groups. The first group, positively correlated with the traffic count consisted of phenanthrene, acenaphthene, indenol (1,2,3-cd) pyrene, benzo(k)fluoranthene, benzo(a)pyrene, benzo(ghi)perylene, benzo(a)anthracene and chrysene, all positively correlated with each other. The second group of compounds, positively correlated with each other but negatively with the traffic count, consisted of dibenzo(ah)anthracene, naphthalene, anthracene, fluoranthene, acenaphthene and fluorene. The third group consisted only of pyrene, which had a positive correlation with most of the compounds from the second group apart from dibenzo(ah)anthracene and was not correlated with the traffic count in any way.
Photodynamic antimicrobial chemotherapy of asymmetric porphyrin-silver conjugates towards photoinactivation of Staphylococcus aureus

Abstract Asymmetric mono-carboxy-porphyrins, (5-(4-carboxyphenyl)−10,15,20-tris(pentafluorophenyl)porphyrinato zinc(II) (1), 5-(4-carboxyphenyl)−10,15,20-triphenylporphyrinato zinc(II) (2) and 5-(4-carboxyphenyl)−10,15,20-tris(2-thienyl)porphyrinato zinc(II) (3), were linked to Ag nanoparticles (AgNPs) through amide bonds and self-assembly (the latter only for 3). The porphyrins and conjugates were used for photodynamic antimicrobial chemotherapy (PACT) against Staphylococcus aureus. PACT uses singlet oxygen for antimicrobial activity. Complex 3 and its conjugates had higher singlet oxygen quantum yields and higher log reduction when compared with the rest of the porphyrins and corresponding conjugates. These high log reductions for 3 and its conjugate were attributed to the presence of sulfur groups whereby there was more interaction with the bacterial membrane. Graphical Abstract
The Second International Conference on Bioinformatics, Supercomputing and Complex Genome Analysis

This conference was held in St. Petersburg Beach, Florida June 4--7, 1992. The purpose of this conference was to provide a forum for exchange of state-of-the-art information in the field of the human genome. This provided an opportunity to gain firsthand knowledge of the scope, direction, and future prospects of information and computing in complex genome analysis. Topics of discussion include the following: Linguistic approaches; applications of neural networks; databases; genome map; genome sequence analysis; mapping and sequencing; and computer technologies and mathematical approaches. Individual papers are processed separately for inclusion in the appropriate data bases.
Technology Transfer and Innovation for Low-Carbon Development

Technological revolutions have increased the world’s wealth to a level that was once unimaginable. They have done so unevenly, however, and in ways that have accelerated climate change. Technology Transfer and Innovation for Low-Carbon Development argues that most of the emissions reductions required to achieve the Paris Agreement goals can be reached through the global deployment of existing and commercially proven low-carbon technologies (LCTs). Deploying LCTs from high-income countries, which account for 80 percent of all LCT innovations and 70 percent of all LCT exports, to developing countries, where they are needed most, will not be easy; but the evidence is clear that it can be done. Transferring LCTs is not only necessary to meet the climate targets, but it is also an opportunity to achieve development goals. The policies needed to deploy LCTs to developing countries could raise output and employment while yielding welfare benefits, such as reduced air and water pollution. Moreover, adopting LCT offers an opportunity for countries to benefit from participation in global value chains and to become LCT producers and exporters.
Interferon‐β activates multiple signaling cascades in primary human microglia

Microglia, the resident brain macrophages, are the principal cells involved in the regulation of inflammatory and antimicrobial responses in the CNS. Interferon‐β (IFNβ) is an antiviral cytokine induced by viral infection or following non‐specific inflammatory challenges of the CNS. Because of the well‐known anti‐inflammatory properties of IFNβ, it is also used to treat multiple sclerosis, an inflammatory CNS disease. Despite the importance of IFNβ signaling in CNS cells, little has been studied, particularly in microglia. In this report, we investigated the molecular mechanisms underlying IFNβ‐induced β‐chemokine expression in primary human fetal microglia. Multiple signaling cascades are activated in microglia by IFNβ, including nuclear factor‐κB (NF‐κB), activator protein‐1 (AP‐1) and Jak/Stat. IFNβ induced IκBα degradation and NF‐κB (p65:p50) DNA binding. Inhibition of NF‐κB by either adenoviral transduction of a super repressor IκBα, or an antioxidant inhibitor of NF‐κB reduced expression of the β‐chemokines, regulated upon activation, normal T‐cell expressed and secreted (RANTES) and macrophage inflammatory protein (MIP)‐1β. IFNβ also induced phosphorylation of extracellular signal‐regulated kinase (ERK) mitogen‐activated protein kinase, and the MAP kinase kinase 1 (MEK1) inhibitor PD98059 dose‐dependently inhibited β‐chemokine mRNA and protein expression. PD98059 did not inhibit NF‐κB binding, demonstrating that ERK was not responsible for NF‐κB activation. Two downstream targets of ERK were identified in microglia: AP‐1 and Stat1. IFNβ induced AP‐1 nuclear binding activity in microglia and this was suppressed by PD98059. Additionally, IFNβ induced Stat1 phosphorylation at both tyrosine 701 (Y701) and serine 727 (S727) residues. S727 phosphorylation of Stat1, which is known to be required for maximal transcriptional activation, was inhibited by PD98059. Our results demonstrating multiple signaling cascades initiated by IFNβ in primary human microglia are novel and have implications for inflammatory and infectious diseases of the CNS.
First Report of Eriosoma lanigerum (Hausmann, 1802) (Hemiptera: Aphididae) on the Apple tree Crop in Espirito Santo State, Brazil

The apple tree is affected by a large variety of phytophagous plants. Woolly apple aphid in apple trees, Eriosoma lanigerum (Hausmann) (Hemiptera: Aphididae) are from North America. The main host of this insect is the plant Ulmus americana L. and the secondary host is the apple tree, where it develops throughout the year. Collects were carried out in pioneer municipalities in the planting of apple trees in the state of Espirito Santo, being cultivated Eva, Gala and Fuji varieties. The collections took place in the municipality of Santa Teresa, Santa Maria de Jetiba and Mantenopolis. Samples were taken at the stages of vegetative development and apple production. In this study, the occurrence of this insect was recorded in apple orchards in the state of Espirito Santo, where the presence of E. lanigerum was observed in all the samples, attacking the trunk, new shoots, roots, shoots and fruits between the planting lines.
Weighted Null Vector Initialization and its Application to Phase Retrieval

Phase retrieval problem is an nonlinear inverse problem of recovering real- or complex-valued signal from quadratic measurements, which arises in various applications. The best-known algorithms for solving this problem are non-convex methods starting with spectral initializers that provide an initial point within a local basin sufficiently close to the target signal. This paper introduces a simple method, called weighted null vector initialization (WNI), which can be used to compute accurate initialization vectors for solving non-convex phase retrieval. The introduced WNI method is more robust against measurement noise and outperforms the best spectral initializer, and null initializer. Simulation results are provided to illustrate the effectiveness of the proposed method.
Rapport d'étude - Le touladi du lac Témiscouata.

Ce rapport presente les resultats du projet de recherche sur le touladi du lac Temiscouata. Sommes toutes, les conditions abiotiques sont adequates pour la fraie du touladi et l’incubation des oeufs. Les mouvements des touladis matures lors de la fraie sont similaires a ce qui a ete observe pour cette espece. Ils consistent en des agglomerations sur les sites a la tombee du jour lors de l’automne durant des periodes de forts vents et de tempetes. Il a ete note que les poissons restent generalement sous les 10 metres de profondeur lors de la periode de reproduction, alors que l’habitat optimal du touladi pendant la periode estivale est situe sous les 15 metres. Un colmatage partiel des interstices apparait evident. Cependant, le taux normal de sedimentation pendant la periode estivale, ainsi que la presence de fort courant, semble indiquer que le colmatage n’est pas due a des conditions particulieres puisque les taux estimes bouchent les interstices au plus en 68,29 ans. La population de touladi mature dans le lac a ete estimee a 6566 individus ce qui a permis de demontrer qu’environ 83,6% des oeufs ne restent pas sur les sites de fraie.
Extended data: Estimating the overdispersion in COVID-19 transmission using outbreak sizes outside China

Supplementary figures and underlying data accompanying Endo et al. "Estimating the overdispersion in COVID-19 transmission using outbreak sizes outside China". No primary data collection was involved in this study. All data used are from: World Health Organization. Coronavirus disease 2019 (COVID-19) Situation Report – 38. 2020; COVID2019.app - LIVE stats and graphs. 2020 [cited 4 Mar 2020].
Common-mode noise modelling and resonant estimation in a three-phase motor drive system: 9-150 kHz frequency range

This paper presents an equivalent circuit impedance-based estimation method of resonances in a three-phase motor drive system to predict common-mode (CM) noise circulations in 9-150 kHz frequency range, which is not considered so far in electromagnetic interference (EMI) analysis. The paper verifies the presented method by analyzing emission spectrums of CM currents in the three-phase system. The impact of EMI filter, DC-link filter and AC motor models on the generated common mode noise at 9-150 kHz range is also investigated using the predicted equivalent impedance results at the CM voltage source. It is found, there is a high probability to have resonances within 9-150 kHz range due to the components of the drive system. Hence, the work presented is useful to model and predict the possible resonances in the whole drive system that unnecessarily increases the CM noise at this frequency range. The presented estimation method not only enables the ability to early recognition of CM current emissions injected from the drive system to the grid but also supports EMI filter design or modification for 9-150 kHz frequency range. Further, this approach significantly contributes to accelerating the drive products development and entering the market after complying the future standards.
A Pasteurella pneumotropica Strain of Mouse Origin Colonizes Rats but is Out Competed by a P. pneumotropica Strain of Rat Origin

Mouse and rat Pasteurellaceae have been found to differ in phenotypic characteristics but both animal speciesÂ may be infected by each otherâ€™s bacterial strains. We explored the possibility that a mouse PasteurellaÂ strain colonizing rats would be out competed by a subsequent infection of a rat Pasteurella strain. Â Rats were dosed intranasally and orally with the mouse P. pneumotropica biotype Jawetz strain NCTCÂ 8141T and exposed to pen-mates infected with the rat P. pneumotropica biotype Heyl strain SSI P331 byÂ co-housing. Â Rats were tested by PCR using primer sets developed for the specific detection of each biotype respectively. Â The co-housing and exposure of rats initially infected by the mouse P. pneumotropica with pen-mates harbouringÂ the rat P. pneumotropica led to disappearance of the mouse bacterium from the rats. Â Our results question the suitability of Pasteurellaceae from contemporary laboratory animals to elucidateÂ associations between bacterial properties and host species. Â
Synaptotagmin 1 is the Ca2+ Sensor for the Endocytic Kinetics of Clathrin-Mediated Endocytosis

After neurotransmitter release via exocytosis, synaptic vesicles are locally retrieved, re-filled and made readily available for the next round of release at the synapse (Heuser & Reese, 1973; Miller & Heuser, 1984). While the role of Ca2+ has long been established to be essential in triggering exocytosis (Neher and Sakaba, 2008), recent studies indicate a direct role of Ca2+ in endocytosis as well (Wu et al., 2007). Along this line, synaptotagmin 1 (Syt1), a synaptic vesicular protein, , is well established as the Ca2+ sensor to trigger vesicle exocytosis (Chapman, 2008) and recent evidence indicates that this protein may also play Ca2+ dependent roles in endocytosis (Nicholson-Tomishima & Ryan, 2004, please recite more papers for this). However, the molecular details for the role of Ca2+ and Syt1 in vesicle endocytosis remains poorly understood. In the present study, by taking advantages of millisecond time resolution of cell-attached capacitance measurements to monitor clathrin-mediated endocytosis (CME), the classic retrieval pathway at synaptic terminals (Murthy & De Camilli, 2003; Granseth et al., 2006), I demonstrate for the first time that: 1) the dynamics of vesicle fission during CME is both Ca2+- and Syt1- dependent; 2) Syt1 may serve as the biochemical Ca2+sensor of CME and 3) that the interaction between Syt1 and phosphatidylserine, a putative Ca2+ dependent interaction, may be critical for the Ca2+ sensing role of Syt1 in CME kinetics
Cryptic species in the Pyropia yezoensis complex (Bangiales, Rhodophyta): Sympatric occurrence of two cryptic species even on same rocks

In a previous study on wild populations of Pyropia, the occurrence of two possible new species (Pyropia sp. 2 and Pyropia sp. 3) which are closely related to the two commercially important Pyropia species, P. yezoensis and P. tenera, was confirmed as the result of molecular phylogenetic analyses. To characterize the morphological features of the two wild Pyropia species, we collected Pyropia blades in a natural population in which Pyropia sp. 3 was known to occur, and carried out molecular identification before detailed morphological observations. Through the molecular identification we found, unexpectedly, that Pyropia sp. 2 blades grew sympatrically in the same site. Therefore, after molecular identification, we examined in detail the external morphology and anatomy of the two wild Pyropia species using more than 10 blades each. As a result, it is concluded that all of the blades of the two species are morphologically identical to P. yezoensis, but distinct from P. tenera. It is therefore considered that both of the two wild Pyropia species are cryptic species within the P. yezoensis complex. Furthermore, this study revealed that the two cryptic species grew sympatrically, even on the same rocks within the natural habitat.
Biomarcadores en la sepsis y su valor predictivo

Introduccion: La sepsis es una enfermedad causante de una alta mortalidad y es reconocida mundialmente. La incorporacion de nuevos biomarcadores posibilita la obtencion de un diagnostico rapido y preciso. Objetivo: Determinar la capacidad predictiva en un grupo de biomarcadores en pacientes con sepsis. Metodos: Se realizo un estudio de casos y controles con 70 pacientes ingresados en la Unidad de Cuidados Intensivos de Adultos del Hospital Militar Central Dr. Luis Diaz, entre enero de 2015 y enero de 2017. La muestra quedo dividida en 51 pacientes (grupo de casos) y 19 (grupo control). Se emplearon variables demograficas, la estadia y la mortalidad; y se determinaron los biomarcadores mas sensibles para el diagnostico inicial y de mejor valor predictivo. Se empleo la estadistica descriptiva y se realizaron pruebas diagnosticas con mas de dos resultados (Curva ROC). Resultados: El grupo de edades mas representativo fue el de 66-76 anos, con un ligero predominio de varones. Se reporto incremento de la mortalidad en estadios mas avanzados de la sepsis. El lactato fue el marcador con mayor sensibilidad. Conclusiones: De los biomarcadores clasicos, el lactato, la proteina C reactiva, el hematocrito y tiempo de protrombina fueron los de mayor sensibilidad. A pesar de que tienen una baja especificidad, son utiles para el manejo del paciente septico, pues poseen valores mas elevados cuanto mayor es el estadio de la sepsis o el riesgo de fallecer.
Blood biochemistry of poultry fed with grape by-products

An experiment was conducted to determine the effects of the inclusion of the grape by-products (Vitis vinifera) as growth promoters in diet of chicken on blood biochemical parameters and cecal pH. Six hundred Ross males chicks were raised from 1 to 21 days of age were allotted in a completely randomized design, with six treatments, inoculated or not with strains of Escherichia coli in 6x2 factorial of five replications, with 10 birds. Each birds received an isonutritive basal diet added of grape by-products or antibiotics according to the following treatments: T1-negative controls; T2-positive control-0,05% of flavomycin and colistin sulphate; T3-0,04% defatted grape seed extract Agrarian, v. 1, n. 1, p. 91-104, jul./set. 2008. 9 2 Agrarian, v.1, n.1, jul./set. 2008 2 (ESUD); T4-0,1% of grape seed (SUI); T5-0,47% of SUI and T6 2,35% of SUI. The inclusion of grape by-products decrease blood levels of triglycerides, but did not influence other variables. The inoculation decreased the levels of blood total protein and increased triglicerideos and glucose, especially when associated with the ESUD. Grape byproducts, such as seeds, can be used to reduce of plasma triglycerides and abdominal fat in poultry. Key-words: blood biochemistry, grape byproducts, growth promoter, poultry.
Multi‐coefficients correlation methods

A composite quantum chemical method is an approximated computational protocol designed to obtain highly accurate energies for different types of interactions. In this review, we summarize the recent advance in the evolution, assessments, and applications of the multi‐coefficients correlation methods (MCCMs) and doubly hybrid MCCMs, especially the recent Wuhan‐Minnesota‐Scaling method, for accurate calculations of Born–Oppenheimer energies of molecular systems. The review gives an overview of the methods along with their performance on the W4‐17 database.