Miracle-dz/UniFAR-FTUs huggingface dataset:
Correlation of Her-2/Neu and Tp53 Expressions with Clinicopathologic Characteristics in Infiltrative Ductal Breast Carcinomas

Objective: To review Her-2/neu and Tp53 status and their correlation with all other prognostic clinicopathologic features of infiltrative ductal breast carcinomas. Materials and Methods: This cross sectional study was performed on 139 patients with infiltrative ductal breast carcinoma who were diagnosed between May 2000 and March 2006 at the surgery and pathology departments of Alzahra Hospital, Isfahan, Iran. Immunostaining (IHC) for Tp53 and Her-2/neu were performed on formalin-fixed, paraffin-embedded tissues based on an avidin-biotinperoxidase complex technique. The relationship of these markers with clinicpathologic parameters including age, axillary lymph nodes status, tumor size and histological grade were evaluated. Results: It was found out that Her-2/neu-positive cases were greater among metastatic lymph nodes than in patients without metastasis, however it was not significant (p=0.1). A significant association was also observed between Her-2/neu status and tumor grading (p=0.01). On the contrary, no association was found with other clinicpathologic parameters. In this study, Tp53 presentation in high-grade carcinomas was significantly more as compared to low grade ones (p=0.03). A significant association was also observed between Tp53 and tumor size (p =0.01). There was no association with menopausal status and lymph node status. Conclusion: IHC determined that Her-2/neu and Tp53 expressions are not associated with nodal and menopause status. Conversely, a correlation was found between Her-2/neu, Tp53 expressions and high histological grade of tumor. However, to validate these findings, long-term prospective studies on patients’ survival are necessary.
The prognosis of HIV-infected patients with diffuse large B-cell lymphoma treated with chemotherapy and highly active antiretroviral therapy is similar to that of HIV-negative patients receiving chemotherapy

In the era of highly active antiretroviral treatment (HAART), the prognosis of AIDS-related lymphomas might be similar to that of aggressive Bcell lymphomas in human immunodeficiency (HIV)-negative patients. In this study we found that HIV-infected patients with diffuse large B-cell lymphoma treated with cyclophosphamide, hydroxydoxorubicin, vincristine and prednisone (CHOP) and HAART showed a similar response rate to chemotherapy, disease-free survival and overall survival as those of HIV-negative patients receiving CHOP.
Measurement and analysis of content diffusion characteristics in opportunity environmentswith Spark

Opportunity networks provide a chance to offload the tremendous cellular traffic generated by sharing popular content on mobile networks. Analyzing the content spread characteristics in real opportunity environments can discover important clues for traffic offloading decision making. However, relevant published work is very limited since it is not easy to collect data from real environments. In this study, we elaborate the analysis on the dataset collected from a real opportunity environment formed by the users of Xender, which is one of the leading mobile applications for content sharing. To discover content transmission characteristics, scale, speed, and type analyses are implemented on the dataset. The analysis results show that file transmission has obvious periodicity, that only a very small fraction of files spread widely, and that application files have much higher probability to be popular than other files. We also propose a solution to maximize file spread scales, which is very helpful for forecasting popular files. The experimental results verify the effectiveness and usefulness of our solution.
External hashing with limited internal storage

The following problem is studied: How, and to what extent, can the retrieval speed of external hashing be improved by storing a small amount of extra information in internal storage? Several algorithms that guarantee retrieval in one access are developed and analyzed. In the first part of the paper, a restricted class of algorithms is studied, and a lower bound on the amount of extra storage is derived. An algorithm that achieves this bound, up to a constant difference, is also given. In the second part of the paper a number of restrictions are relaxed and several more practical algorithms are developed and analyzed. The last one, in particular, is very simple and efficient, allowing retrieval in one access using only a fixed number of bits of extra internal storage per bucket. The amount of extra internal storage depends on several factors, but it is typically very small: only a fraction of a bit per record stored. The cost of inserting a record is also analyzed and found to be low. Taking all factors into account, this algorithm is highly competitive for applications requiring very fast retrieval.
Contextualizing International Voluntary Guidelines into Country Specific Land Investment Governance Systems: Experience from Tanzania By

This preliminary study involved consultation of responsible district government officials and relevant Civil Society Organizations (CSOs) on various issues related to land and investments. Among other areas, the Southern Agricultural Growth Corridor of Tanzania (SAGCOT) was selected as a study site and study used the Focus Group Discussions (FGDs) to obtain information. Questionnaire designed reflected land investment governance process thematic areas. This ranged from investment pre-planning and organization stage, negotiation and preparation of investments contracts to implementation of investments. Throughout this paper, different issues are discussed including but not limited to inadequate awareness and understanding of Tanzania Investment Centre (TIC) mandate and the land allocation process among land based investment stakeholders; Practices that do not adhere to Free, Prior and Informed Consent (FPIC) principle; Existing compensation practices that are conducted in an inadequately and vague processes ; Dispute resolution mechanisms that are inadequately culturally sensitive and with a bias against women and evidences of weak land-based investment monitoring and evaluation system. The paper concludes that there is inadequate implementation of land investment governance good practices principles in Tanzania. The study further recommends Civil Society Organizations (CSOs), and government to address highlighted gaps in land investment governance.
CAN WE STAY ON TARGET? A REVIEW OF HYPERTENSION TREATMENT IN THE ELDERLY

Hypertension is a leading cause of mortality. The prevalence is reported to be between 40 and 80 percent in those aged over 80 years. There has historically been a lack of consensus concerning the identification and treatment of hypertension in the elderly, making this a research priority. Recent studies and guidelines focusing on the treatment of hypertension in elderly patients have demonstrated the benefit of treatment, but suggest higher targets. However, a comprehensive assessment of each patient’s comorbidities, frailty, risk of falls, and cognition is crucial. Each of these variables has the potential to impact therapy, targets, and follow-up requirements.
An Epidemiological Investigation of a Scarlet Fever Outbreak at a Kindergarten in Taichung City

Scarlet fever is caused primarily by group A β-hemolytic streptococci. Symptoms include: acute fever, sore throat, bloody eyes, nausea, vomiting, fatigue, headache, loss of appetite, tonsillitis, rash, decortication, or strawberry tongue. Most patients will recover, with some developing complications such as acute glomerulonephritis and acute rheumatic fever. For prevention, an epidemiological investigation of the infection to understand the
Attenuation properties of electrically large periodic structures applying FEM

Avoiding electromagnetic field contamination of large rooms is a very cumbersome and expensive task, especially when a widespread frequency range has to be considered. Often, windows serve as vents. This implies the use of absorbing structures with electrically large feedthroughs at a certain mechanical robustness. In this paper the attention has been drawn to metallic, periodic structures like arrays of rectangular waveguides. Electromagnetic waves at different incident angles strike the structure whereas the influence of its thickness will be varied, as well. The prescription of the attenuation properties will be given. All results will be achieved with the aid of finite element computations.
Efficient Image Transfer Rate Control and Compression Using Pyramidal Layer Format

The pyramidal layer format's main purpose is to store images in an efficient manner for both transfer rate control and compression purposes. It involves lossless compression and is elegantly designed to ensure a proper balance between the user experience and the bandwidth constraints, as well as between texture information and edge quality. Keywords— frequency separation, image compression, PLF image file format, progressive transfer.
Visfatin , Omentin-1 and lipid profile in patients with psoriasis and their relation to Disease severity

and tissue levels of visfatin in psoriasis group were significantly higher than controls (p-value=0.001, 0.04 respectively). There was a significant positive correlation between serum (r and tissue visfatin levels and PASI score = p = 0.003 and r = 0.39, p = 0.001. Serum omentin-1 level was significally lower in patients group than controls (p-value = 0.017). Also, LDL was significally higher (p-value = 0.029), HDL was significally lower in psoriasis group than controls (p-value = 0.001). Psoriasis is a chronic, autoimmune, and inflammatory disease of unknown etiology. The association of the novel adipokines visfatin and omentin-1 with psoriasis is still obscure. Data concerning other inflammatory diseases suggest a possible role of these adipokines in the pathophysiology of psoriasis. The present study represents a retrospective case –control study carried on 28 patients with plaque-type psoriasis and 30 healthy controls, serum and tissue visfatin and omentin-1 levels were measured by using the ELISA technique. Our results showed that Serum
Describing compartmentalization in the Inner hind wings of three local populations of the coconut leaf beetle, Plesispa reichei

This study was conducted to describe compartmentalization in the inner wings of three local populations of two-colored coconut leaf beetle, Plesispa reichei. Modularity and Integration Analysis (MINT) tested 5 a priori models of variational modularity in multidimensional data. Using γ* (Gamma*) test for goodness of fit (GoF) statistics comparing the observed and expected covariance matrices show that the inner wing is composed of 3 mutually exclusive and integrated developmental modules. One of the three populations however differ not only between the left and right wing but also based on the priority models of compartmentalization. While variations between populations were observed, results still confirm the idea that the modules observed in the wings are morphological units with clear spatial boundaries and are tightly integrated.
A multi-functional and multi-compartment constructed wetland to support urban waterway restoration

This study assessed the significance of a multi-functional and multi-compartment constructed wetland (CW) implemented to restore a degraded urban waterway in Western Australia. The wetland was initially constructed as a surface flow system, then modified through the incorporation of the additional laterite-based subsurface flow system, with the potential for operation of a recirculation scheme and groundwater top-up during low water flows in summer. The CW performance was assessed by comparing nitrogen (N) and phosphorus (P) attenuation during base flow, high flow and episodic storm flow conditions. The performance varied from approximately 41% total nitrogen (TN) and 66% total phosphorus (TP) loads reduction during storm events, increasing up to 62% TN and 99% TP during low flow and summer recirculation periods. In overall, the CW attenuated about 45% TN and 65% TP loads from being delivered to the downstream sensitive river between 2009 and 2015. The CW design proved to be not only highly effective at reducing nutrient loads, but also improved the ecological services of the urban waterway by providing a diverse area for habitat and recreational activities.
The risk of falls in elderly, community-dwelling women with exudative age-related macular degeneration

Purpose: To prospectively determine physiologic risk factors for falls, and falls incidence, among elderly, community-dwelling women with exudative age-related macular degeneration (AMD). Design: 1) Cross-sectional, and 2) prospective longitudinal cohort study. Methods: In our cross-sectional study, 115 community-dwelling women aged 70 or over with exudative AMD were assessed for fall risk by Physiological Profile Assessment (PPA). The PPA generates a personalized risk score by comparing participants' scores on fall risk factor measures to a healthy Australian population. A second comparison group consisted of 34 normally-sighted women aged 70 or older without exudative AMD. In our cohort study, we followed 115 community-dwelling women aged 70 or over with exudative AMD and 93 normally-sighted women without AMD for 6 months and compared the falls incidence per group. Falls were measured by monthly telephone follow up. Multivariate negative binomial regression was used to model the association between falls incidence, and exudative AMD. Results: In our cross-sectional study, we measured mean overall fall risk scores of 3.26 in the AMD group and 0.96 in the non-AMD group (p<0.0001). The AMD group as a whole scored significantly lower on measures of vision, postural sway, and reaction time, compared to the Australian population, but not on proprioception or quadriceps strength. In contrast, the average for the non-AMD group was within one standard deviation of the mean of the Australian cohort on all PPA measures except reaction time (z=-1.07). The fall rate was 82 falls per 100 person years for women with AMD, and 28 falls per 100 person years for women without AMD. Although AMD, comorbidities, and self-reported 12 month fall history were significant univariate predictors of falls, on multivariate modeling only AMD remained significant. The adjusted relative risk for having a fall over 6 months, for women with AMD compared to the non-AMD cohort, was 3.15 (95% confidence interval = 1.47 6.74). Conclusion: Elderly women with exudative AMD are at a significantly higher risk of falls than those without AMD, by falls risk profile as well as 6-month falls incidence.
Cypermethrin-Induced Anti-Fertility and the Ameliorating Effect of Lycopene Supplementationin Female Rats

This study aimed at evaluating the potential anti-fertility amelioration of Lycopene co-administered with Cypermethrin(CYP) in female Sprague-Dawley rats. Twenty eight sexually matured female rats were divided into seven groups (A-G). Group A-control, B given CYP only, C and D, given CYP+5,000 and 10,000mg/kg/bw/day of processed S. lycopersicum, E and F, CYP+ 5,000 and 10,000mg/kg/bw/day of Fresh S. lycopersicum, while G were given 10mg/kg/bw/day of pure Lycopene(LYP) for 70days. Each exposed female was introduced to unexposed male for mating. Body weight of female rats recorded throughout this period while upon delivery, other fertility indices were recorded. Result showed no significant difference P>0.05 in the maternal weight and a significant difference between the litter size of the control and treatment groups P<0.05. Dams in control group delivered live pups, 25% in grps B-G, 50% in grp D and 0% in grp E. Other female rats later dissected had no pups, dead or alive. This shows that CYP is an,endocrine disrupting chemical induced pseudo-pregnancy and fetotoxicity. Lycopene showed no protective effect on Cypermethrininduced reproductive toxicity in the female rats
Preovulatory stasis and dystocia in oviparous lizards

This case report was provided by raffaele Melidone, dr. med. vet. ; Joyce S. Knoll, vMd, Phd, dACvP; and Nicola Parry, BSc, MSc, BvSc, dACvP, department of Biomedical Sciences, Cummings School of veterinary Medicine, Tufts University, North Grafton, MA 01536. Preovulatory stasis and dystocia in oviparous lizards Raffaele Melidone, Dr. med. vet. ; Joyce S. Knoll, VMD, PhD, DACVP; and Nicola Parry, BSc, MSc, BVSc, DACVP
Confucius and Chinese Philosophical Impact on Modern Korea and Japan

The purpose of this conceptual paper is to understand the role of Confucianism Chinese philosophy in influencing modern Korea and Japan. This paper found that Confucianism had a significant impact on current modern world. However, it has been a selective application. Confucianism still has vital value within the modern times; this paper examined to expound the modern significance of Confucianism, In particular, it is clear that Confucianism has had profound influence on world politics and foreign policy. The major focus was on the impact of Confucianism on modern world politics and foreign policy. In the field of international relations and foreign policy analysis, it is well known that ideas are always critical to any changes of a country’s foreign policy. The author examined the influence of Confucianism Chinese philosophy on Chinese domestic politics and modern politics. The analysis covered recent arguments about the role of Confucianism from several leading contemporary thinkers. Korea and Japan spent much time culturally and politically under the influence of China, Which brought Confucianism to these countries? Korean, as well as Japanese communication is heavily influenced by Confucian traditional values. It is demonstrated that those values are changing. But they seem to be better preserved in Korean society based upon the educational system of teaching moral values, nationalism, and arrested Cultural Revolution.
Food-borne bacterial load in fresh and frozen fish sold in Mauritius

Microbial load of fresh Lethrinus nebulosus (locally known as Capitaine) and Siganus sutor (locally known as Cordonnier) was compared during summer and winter in Mauritius. Fresh fish samples were collected from different regions of Mauritius during summer and winter. The bacterial load of the fresh fish was found to be higher (1.2x 105CFU/g) during the hot season (p < 0.05). Significant differences in staphylococcal count were also observed among the different fish species (p < 0.05) though the values abided by the limits. Furthermore, frozen L. nebulosus showed a significant difference in the total bacterial load by 100 fold and 10 fold for staphylococcal count compared to the fresh samples of the same fish species. Emphasis was also placed on the isolation of the probable presence of the main food pathogens encountered on fish namely Enterococcus and Vibrio species. 16S ribosomal DNA Sequencing revealed the presence of Vibrio alginolyticus and Enterococcus cloacae. Improper handling practices by the fish mongers and sellers/vendors and inadequate storage temperature affected the bacterial load of fresh fish. Both fresh and frozen fish in Mauritius have an acceptable total microbial load and can be assumed to be safe for consumption.
E-Commerce: An Overview of Adoption and Its Effective Implementation

Electronic commerce is a concept that is gaining acceptance in businesses, like other papers related to ecommerce this paper objective was to shed light on e-commerce adoption, trend and issues that are facilitating and hindering its effectiveness through comprehensive reviewing of literatures in the related area. It is observed that there has been a growing trend of e-commerce adoption globally even to the least developing countries, which is motivated by e-commerce adoption benefits by businesses such as expansion of business opportunities, businesses enjoying being cost effectiveness with widened coverage and increased customers services. There are challenges highlighted for effective e-commerce adoption and implementation such as poor e-commerce supporting infrastructures for instance reliable Internet connections, poor transport and logistics system also presence of socio regulatory barriers. Moreover it was recommended for better improvement of e-commerce affordable and reliable Internet facilities is vital for instance the intensity, the cost for accessing Internet, also reasonable level of e-readiness to all levels of business is important to its effectiveness, formulation of Government policies that catalyze improvement of e-commerce effectiveness is similarly vital.
Evaluation of Trace Elemental Levels as Pollution Indicators in an Abandoned Gold Mine Dump in Ekurhuleni Area, South Africa

In the Blesbokspruit area of Ekuhurleni, South Africa, previous gold mining activities resulted in many tailings dump sites. 20 representative soil samples were used in describing the distribution of metals. The soils were very strongly acidic ranging from 3.86 to 4.34 with a low cation exchange capacity (CEC). Based on X-ray fluorescence (XRF) analysis, elemental composition of the soils revealed average values of major elements such as Na2O (0.18%), MgO (0.63%), Al2O3 (6.51%), SiO2 (81.83%), P2O5 (0.04%), SO3 (3.40%), K2O (1.98%), CaO (0.45%), TiO2 (0.51%), Cr2O3 (0.17%), MnO (0.04%), Fe2O3 (3.59%), NiO (0.04%), As2O3 (0.02%), with Rb2O and SrO falling below 0.01%. Trace metals (TM) contamination levels in the soils were evaluated using various pollution indices which revealed that over 60% of the soils were between the high degree and the ultra-high degree of contamination classes. The concentration of various trace metals varies from 860.3–862.6 mg/kg for Cr; 324.9–328.4 mg/kg for Al; 200.9–203.4 mg/kg for As; 130.1–136.2 mg/kg for Fe; 121.9–125.8 mg/kg for Pb; 27.3–30.2 mg/kg for Co; 23.8–26.8 mg/kg for Ni; 7.2–9.2 mg/kg for Ti; 7.1–9.2 mg/kg for Cd; 4.0–5.6 mg/kg for Zn and 0.1–0.6 mg/kg for Cu.
The immunopathology of chronic suppurative lung disease in Northern Territory children

Northern Territory Indigenous children experience a high burden of chronic suppurative lung disease (CSLD) associated with recurrent lower respiratory infection. There are currently limited data to guide effective long-term management strategies for CSLD. This thesis investigates the role of the immune response, particularly in relation to non-typeable Haemophilus influenzae (NTHi), in the pathogenesis of chronic suppurative lung disease in Northern Territory children. The findings from this thesis provide biological evidence in support of novel management strategies to improve the clinical outcome for Northern Territory children with CSLD. Principal findings: 1. A prospective evaluation study showed that flexible bronchoscopy with lavage substantially contributes to the clinical management of children with CSLD by identifying airway eosinophilia and respiratory pathogens not addressed by current empiric therapies. 2. In vitro studies of innate, and adaptive immune responses to NTHi showed that: a. Children with CSLD generate a functionally distinct cell-mediated immune phenotype in response to NTHi compared with respiratory-healthy children. b. The NTHi-driven cytokine profile in children with CSLD is associated with mechanisms regulating inflammation in the lungs. 3. A study of children vaccinated with a Pneumococcal H. influenzae Protein D conjugate vaccine provided proof-of-concept that the functional immune profile can be modified in children with CSLD. The findings from this thesis contribute to the development of novel management strategies for CSLD in Northern Territory children by identifying factors of the immune response, likely contributing to the pathogenesis of CSLD, that may be targeted by novel therapeutic interventions. These data lay the foundation for studies to evaluate the effect of novel interventions on the clinical outcomes of Northern Territory children with CSLD.