Miracle-dz/UniFAR-FTUs huggingface dataset:
Physical medicine and rehabilitation.

TO those interested in the field of physical medicine and rehabilitation the major sources of publications in this country are the Archives of Physical Medicine and Rehabilitation, the American Journal of Physical Medicine and the Physical Therapy Review. In addition, of course, articles appear in the various specialty journals, all of which are now interested in rehabilitation and present papers of interest to specialists in physical medicine (physiatrists) as well as specialists in their own fields. The present review of literature in recent years is devoted to selections of certain articles found in these journals and also those .
Predicting Fed Forecasts

Monetary policy decisions by the Fed's Federal Open Market Committee have attracted considerable attention in recent years, especially with quantitative easing through large-scale asset purchases, the introduction of forward guidance, and increases in the federal funds rate. The FOMCâ€™s decisions are based in part on the Greenbook forecasts, which are economic forecasts produced by the Federal Reserve Boardâ€™s staff and which are presented to the FOMC prior to their policy meetings. Drawing on Stekler and Symingtonâ€™s (2016) textual analysis of the minutes of the FOMC meetings, the current paper shows that those minutes provide a proximate mechanism for inferring the Fed staff's Greenbook forecasts of the U.S. real GDP growth rate, years before the Greenbook's public release. The FOMC minutes are thus highly informative about a key input to monetary policymaking.
Treatment With Neutralizing Antibodies Specific for IL-1β Prevents Cyclophosphamide-Induced Diabetes in Nonobese Diabetic Mice

Interleukin-1 (IL-1) has been shown to be involved in the pathogenesis of IDDM, but it is not clear which form, IL-1α or IL-1β, is predominantly implicated. In this study, we have evaluated the contribution of IL-1β by treating diabetes-prone nonobese diabetic (NOD) mice with specific neutralizing antibodies. First, we assessed the neutralizing potential of these antibodies in C57BL/6 mice under acute septic shock by measuring IL-1β in sera 4 h after lipopolysaccharide injection. One milligram and 0.1 mg of anti–IL-1β antibodies (Abs) were capable of neutralizing the IL-1β produced, and the effect persisted for at least 5 days. Second, we evaluated the role of IL-1β in the cyclophosphamide (CY)-accelerated model of diabetes. Nondiabetic male NOD mice were injected with 200 mg/kg CY and treated twice weekly with anti–IL-1β Ab. The incidence of diabetes reached 76 and 100% in the control groups treated with 0.25 and 0.1 mg rabbit IgG, respectively. In contrast, only 34% of mice treated with 0.25 mg of anti–IL-1β Ab became diabetic. In the group treated with 0.1 mg of anti–IL-1β Ab, 89% of the mice became diabetic in the same period of time, demonstrating that the protective effect was dose dependent. Our results show that IL-1β is a critical effector molecule in this model of IDDM and that its specific inhibition could be an attractive target for therapeutic intervention.
Incidence and clinical features of acute rheumatic fever in Kayseri, Central Anatolia, 1998–2011

Abstract Background In developing countries, acute rheumatic fever is the most common cause of acquired heart disease in the paediatric and adolescent population. It is believed that vulnerability to developing acute rheumatic fever is associated with several factors such as socio-economic and living conditions. Aim Determine the incidence and clinical characteristics of acute rheumatic fever in the Central Anatolia region of Kayseri within the last 14 years, and to make a comparison of two 7-year periods. Material and methods We performed a retrospective analysis of 624 patients who were diagnosed with acute rheumatic fever at the Department of Pediatric Cardiology in the Medical Faculty of Erciyes University between January, 1998 and December, 2011. Results The mean age of patients was 10.9±2.7 years. The female/male ratio was 1.4. When patients were categorised according to age groups, the largest group represented 376 patients (60.3%) aged between 10 and 14 years. The estimated incidence rate of acute rheumatic fever was 7.4/100,000 in the Central Anatolia region of Kayseri. Among the major findings, the most common included carditis at 54%, arthritis at 35%, Sydenham’s chorea at 25%, and subcutaneous nodules at 0.5%, respectively. No significant difference was found between the first 7-year period and second 7-year period in distributions of age, gender, and major findings. Conclusion Although there has been socio-economic development in Turkey in the recent years, the incidence of acute rheumatic fever is still high in the Central Anatolia region of Kayseri.
Calcium influx through TRPV4 channels modulates the adherens contacts between retinal microvascular endothelial cells

Endothelial cells employ transient receptor potential isoform 4 (TRPV4) channels to sense ambient mechanical and chemical stimuli. In retinal microvascular endothelial cells, TRPV4 channels regulate calcium homeostasis, cytoskeletal signalling and the organization of adherens junctional contacts. Intracellular calcium increases induced by TRPV4 agonists include a significant contribution from calcium release from internal stores. Activation of TRPV4 channels regulates retinal endothelial barriers in vitro and in vivo. TRPV4 sensing may provide a feedback mechanism between sensing shear flow and eicosanoid modulators, vascular permeability and contractility at the inner retinal endothelial barrier.
Understanding the change processes resulting from accreditation of colleges in Saudi Arabia

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Environmental Behavior and MNEs: A Strategy Pulled by Stakeholder Engagement

This research attempts to examine how multinational enterprises (MNEs) from regulated and non-regulated industries shape their environmental strategies with regard to environmental disclosure and performance. Results reveal that regulated (non-regulated) MNEs display worse (better) environmental performance levels and disclose less (more) environmental information than MNEs operating in non-regulated (regulated) environments. We argue that this strategy is set as an answer to cope with legitimacy problems faced by MNEs as well as to respond to increased demands from stakeholder groups. We contend that our findings may contribute to existing literature and be of relevance for practitioners. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
"Right-Throughs, Rings, and Taws": Marbles Pitching Terminology in Trinidad and Tobago.

Marble games, or pitch, are among the moss. widely played of traditional boys' games in Trinidad and Tobago and have declined in the last two decades. Nearly 200 marbles terms found in Trinidad and Tobago English Creole are documeCed. Although most are British in origin, there are East Indian, French Creole, and possible African influences on this lexicon. An analysis of the discourse of marbles talk in its sociocultural context was prompted by its strong positive affect for men who played pitch as boys. Using frameworks from the sociology of games and from studies in language and gender, marbles talk is shown to demonstrate features of masculine gender-linked use of language and games, including highly elaborated rules and strategies, and competitive and confrontational use of language. (Contains 27 references.) (Author/JP) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** "Right-throughs, Rings, and Taws:" Marbles Pitching Terminology in Trinidad and Tobago Lise Winer and Hans E.A. Boos -PERMISSION TO REPRODUCE THIS MATERIAL HAS BEEN GRANTED BY
Inflammatory cytokines and the reactivation of Kaposi's sarcoma-associated herpesvirus lytic replication.

Kaposi's sarcoma (KS) is a complex proliferative lesion long suspected of being dependent on exogenous paracrine signaling molecules to stimulate its proliferative, angiogenic, and inflammatory components. In particular, both clinical and experimental observations have pointed to a potential role for inflammatory cytokines as permissive factors for KS development, but KS pathogenesis is also critically dependent on infection by an exogenous herpesvirus, the KS-associated herpesvirus (KSHV). To examine the possible links between inflammatory cytokines and KSHV replication, we tested for the ability of such cytokines to induce lytic viral reactivation in the latently infected BCBL-1 cell line. Interferon-gamma consistently activated KSHV replication, whereas tumor necrosis factor, interleukin-1, interleukin-2, interleukin-6, granulocyte-macrophage colony stimulating factor, and basic fibroblast growth factor did not. Glucocorticoids also failed to induce lytic KSHV growth in these cells, but ionomycin, a calcium ionophore, induced replication and strongly augmented the known inductive effects of phorbol esters. Interferon-alpha had a dose-dependent inhibitory effect on KSHV induction by ionomycin. The identification of interferon-gamma as an activator and interferon-alpha as an inhibitor of KSHV induction in vitro correlates well with in vivo observations and demonstrates for the first time that inflammatory cytokines can directly modulate KSHV replication.
Incidence of Cervical Intraepithelial Neoplasia in Estonia

Objective This study aimed to assess the incidence of cervical intraepithelial neoplasia (CIN) by grade (CIN 1, CIN 2, CIN 3) and age in Estonia (a country with less developed cervical cancer screening program and high cervical cancer incidence). Materials and Methods This descriptive study uses data from a health insurance fund covering the whole country to estimate the incidence of CIN by grade. CIN case definition was based on specific diagnostic procedures (biopsy, pathological diagnosis, and colposcopy) and/or treatment procedures (excision, local destructive therapy, conization, and hysterectomy) with the CIN-specific diagnosis code (International Statistical Classification of Diseases, 10 Revision) reported on health care claims. Age-specific incidence rates were calculated together with the 95% CIs. Main outcome measure includes CIN grade–specific incidence rate per 1,000 women. Results The estimates for CIN incidence per 1,000 women range from 0.68 to 2.83 for CIN 1, 0.63 to 1.24 for CIN 2, and 0.13 to 0.53 for CIN 3 for narrow (biopsy/pathological diagnosis based) and broad (any CIN-specific diagnostic procedure/treatment based) case definition criteria, respectively. Conclusions Our estimates for cervical dysplasia disease frequency and age distribution are in line with those from other developed countries. Administrative health care resources (such as health insurance fund data) are a valuable source for health research.
Could a virtual agent be warm and competent? investigating user's impressions of agent's non-verbal behaviours

In this abstract we introduce the design of an experiment aimed at investigating how users' impressions of an embodied conversational agent are influenced by agent's non-verbal behaviour. We focus on impressions of warmth and competence, the two fundamental dimensions of social perception. Agent's gestures, arms rest poses and smile frequency are manipulated, as well as users' expectations about agent's competence. We hypothesize that user's judgments will differ according to his expectations, by following the Expectancy Violation Theory proposed by Burgoon and colleagues. We also hypothesize to replicate the results found in our previous study concerning human-human interaction, for example high frequency of smiles will elicit higher warmth and lower competence impressions compared to low frequency of smiles, while arms crossed will elicit low competence and low warmth impressions.
[Cloning and characterization of MTLC, a novel gene in 6q25].

OBJECTIVE To identify and characterize laryngeal cancer related novel genes located on chromosome 6q25. METHODS Electric hybridization was performed in human genome database using EST (expression sequence tag) as probe. Novel genes were deduced by software from positive DNA clones and their cDNAs were amplified by RT-PCR using primers designed according to the sequence of the putative genes. RESULTS A novel gene was cloned successfully. The full length of this gene was about 21 kb. It contained two exons and produced a 1006 bp transcript coding a protein with 235 amino acid residues. It's 5'flanking sequence contained two binding sites of oncoprotein c-Myc, thus it was named MTLC (c-Myc target from laryngeal cancer cells). Homologous assay showed that MTLC exhibited little overall homology to known human proteins but it exhibited good overall homology to mouse MT-MC1 protein with an identity of 78%. The primary structure of MTLC protein contained a nuclear location signal motif, but it did not have other conserved domains. The results of subcellular location experiment showed that MTLC expressed in nuclei of human hepatocellular carcinoma cell line Bel7402 cells, while a wide distribution of MTLC in various tissues was demonstrated by Northern blotting. CONCLUSION MTLC may play an important role as a target gene of c-Myc and as a transcription factor in keeping the normal physiological process of cells.
GPU‐accelerated atom and dynamic bond visualization using hyperballs: A unified algorithm for balls, sticks, and hyperboloids

Ray casting on graphics processing units (GPUs) opens new possibilities for molecular visualization. We describe the implementation and calculation of diverse molecular representations such as licorice, ball‐and‐stick, space‐filling van der Waals spheres, and approximated solvent‐accessible surfaces using GPUs. We introduce HyperBalls, an improved ball‐and‐stick representation replacing tubes, linking the atom spheres by hyperboloids that can smoothly connect them. This type of depiction is particularly useful to represent dynamic phenomena, such as the evolution of noncovalent bonds. It is furthermore well suited to represent coarse‐grained models and spring networks. All these representations can be defined by a single general algebraic equation that is adapted for the ray‐casting technique and is well suited for execution on the GPU. Using GPU capabilities, this implementation can routinely, accurately, and interactively render molecules ranging from a few atoms up to huge macromolecular assemblies with more than 500,000 particles. In simple cases, based only on spheres, we have been able to display up to two million atoms smoothly. © 2011 Wiley Periodicals, Inc. J Comput Chem, 2011
Performing the state: the socio-political dimensions of performance measurement in policy and public services

ABSTRACT This opening paper outlines the rise of public sector performance measurement and performance governance from New Public Management, its trajectory from an administrative tool for organisational monitoring and management, to its insertion into service performance and accountability, to a policy tool defining policy itself. Four key conceptual ways of approaching public sector performance measurement are outlined, and the significance of understanding performance measurement as a socio-technical policy instrument is argued. The paper thematically reviews the papers that follow and how they demonstrate new points of critical analysis in policy studies, including the multiple, mixed and sometimes contradictory purposes for performance measurement, the formation of performance measurement tools, the linkages of performance numbers and governance structures from macro to micro, and the reconfigured roles of professionals in public service delivery. The paper issues a clear challenge to policy researchers to take performance measurement more seriously in understanding the dynamics of policy performance, the achievement of policy objectives, the reframing of policy and the experience of citizens.
Incremental Dynamic Update for Java-Based Smart Cards

One of the most appealing feature for multi-application smart cards is their ability to dynamically download or delete applications once the card has been issued. Applications can be updated by deleting old versions and loading the new ones. Nevertheless, for system components, the update is sligthly more complex because the systems never stop. Indeed, for smart cards based on Java called JavaCard, the virtual machine has a life cycle similar to the card because persistent objects are preserved after the communication sessions with the reader have expired. We present in this paper, our research in dynamic system components updating of JavaCard. Our technique requires a lot of off-card and on-card mechanisms. Our approach uses control flow graph to determine change between versions, a domain specific language to represent the change for minimization of the download overhead throughout the communication link with the card.
Circular Economy Rebound

The so‐called circular economy—the concept of closing material loops to preserve products, parts, and materials in the industrial system and extract their maximum utility—has recently started gaining momentum. The idea of substituting lower‐impact secondary production for environmentally intensive primary production gives the circular economy a strong intuitive environmental appeal. However, proponents of the circular economy have tended to look at the world purely as an engineering system and have overlooked the economic part of the circular economy. Recent research has started to question the core of the circular economy—namely, whether closing material and product loops does, in fact, prevent primary production. In this article, we argue that circular economy activities can increase overall production, which can partially or fully offset their benefits. Because there is a strong parallel in this respect to energy efficiency rebound, we have termed this effect “circular economy rebound. ” Circular economy rebound occurs when circular economy activities, which have lower per‐unit‐production impacts, also cause increased levels of production, reducing their benefit. We describe the mechanisms that cause circular economy rebound, which include the limited ability of secondary products to substitute for primary products, and price effects. We then offer some potential strategies for avoiding circular economy rebound. However, these strategies are unlikely to be attractive to for‐profit firms, so we caution that simply encouraging private firms to find profitable opportunities in the circular economy is likely to cause rebound and lower or eliminate the potential environmental benefits.
Proteome analysis of a plasma membrane‐enriched fraction at the placental feto‐maternal barrier

Purpose: We want to identify proteins that are part of or associated with the plasma membrane of the human feto‐maternal barrier, which is crucially important for nutrient, gas, and waste exchange between the mother and the fetus. All transfer processes occur through one specialized endothelial cell layer, the multinuclear syncytiotrophoblast (STB). Specifically, the apical plasma membrane of the STB interacts with the maternal blood and is the site of initial transport processes across the placenta.
Incremental branching adaptive radix tree

Adaptive indexing has been an area of active research in recent years. Its main concept is to create and maintain indexes adaptively and incrementally based on the incoming workload as a part of the query execution process. Database cracking is the first introduced applicable adaptive indexing paradigm. Despite the effectiveness and lightweight of database cracking, it offers slower lookups when it is compared to modern main memory index structures like adaptive radix tree (ART). ART is a recently proposed main-memory index structure which is designed to be space-efficient yet offers high performance by adapting its internal node size based on the count of keys stored in it. In this paper, we presented IBART (incremental branching adaptive radix tree), a hybrid indexing technique that takes the main concept of database cracking and applies it to ART, generating an adaptive index in terms of its creation and maintenance and also its internal nodes size. For systems of dynamic nature and unpredictable workload, IBART is proven to be more convenient than ART.
The role of a residential learning community in the faith development of Catholic college students

THE ROLE OF A RESIDENTIAL LEARNING COMMUNITY IN THE FAITH DEVELOPMENT OF CATHOLIC COLLEGE STUDENTS Michael J. Stang, Ed.D. Department of Counseling, Adult and Higher Education Northern Illinois University, 2015 Jorge Jeria, Director The college years are a transformative period for undergraduate students, especially in their spiritual development. J.W. Fowler initially proposed the stages of faith model, and S. Parks clarified the unique faith-journey experience of college students. There are many aspects in the lives of college students that influence faith development. Residence halls have long been known as having a great impact on student learning and development. This study examined college-student spiritual development by exploring the impact of a residential learning community on the faith development of Catholic college students. This qualitative study examined the impact of a living-learning community situated in a private residence hall at a public university on the experiences of 13 college students. Data were gathered using a series of three individual interviews with each participant. Data were then analyzed through a thematic coding process. Defining terms was an important introduction to this study. Participants described spirituality as an individual, personal relationship with God and religion as an organized community following a common set of principles and beliefs. Participants viewed faith as the way to put their belief into practice, to make meaning of their actions. Several environmental factors within the residential community emerged as impacting the faith development of college students including opportunities for invitation, peer mentoring, faith-development programming, discernment support, and preparation for faith life after college. Participants also described several factors that influenced their decision to live within the residential community including the facility and amenities, the dining program, and the Catholic nature of the living community. From these findings, several recommendations for student affairs educators were suggested to enhance practices on campus in order to empower spiritual conversations and development. Suggestions for future research also emerged from this study’s results. NORTHERN ILLINOIS UNIVERSITY DEKALB, ILLINOIS