Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluación de las características operativas de la relación proteína / creatinina en orina ocasional para la detección de proteinuria significativa en gestantes con sospecha de preeclampsia

Objective: To analyse the sensitivity and specificity of the protein/creatinine ratio in the urine as a method for detecting proteinuria in women with suspected preeclampsia, considering 24-hour proteinuria as the gold standard. Materials and methods: Cross-sectional study that included women with more than 20 weeks of gestation, admitted to Clinica Universitaria Bolivariana in Medellin because of suspected preeclampsia. Pregnant women with urinary infection at the time of the study, patients with a history of chronic diseases that could cause proteinuria, and women who did not complete the sample collection were excluded. Urine protein/creatinine ratio as well as proteinuria were measured in all the patients included in the study. The correlation between the two tests and the cutoff point for the protein/creatinine ratio with the best performance for the detection of significant proteinuria were evaluated. Results: Overall, 200 urine samples were included and significant proteinuria was found in 27 % of the total number of samples. The protein/creatinine ratio in occasional urine was found to have a high correlation with 24-hour proteinuria (r = 0.775, p < 0.01). The cut-off point with the best performance for detecting significant proteinuria was found to be 0.30 mg /mg, with an 83 % sensitivity and a 98 % specificity, with a positive LR of 60 and a negative LR of 0.17. Conclusion: The protein/creatinine ratio in occasional urine may be used as a fast alternative method for determining the presence of proteinuria in patients with suspected preeclampsia.
Canonical bases arising from quantized enveloping algebras

0.2. We are interested in the problem of constructing bases of U+ as a Q(v) vector space. One class of bases of U+ has been given in [DL]. We call them (or, rather, a slight modification of them, see ? 2) bases of PBW type, since for v = 1, they specialize to bases of U+ of the type provided by the Poincare see however ? 12. )
Choosing Mastectomy: A Qualitative Exploration of the Increasing Mastectomy Rates in Women with Early-Stage Breast Cancer

Context: Rates of Unilateral (UM) and contralateral prophylactic mastectomy (CPM) for earlystage breast cancer (ESBC) have been increasing. Numerous factors for this rise have been suggested including the surgeon’s preference, the patient’s choice and the external environment. Objectives: A grounded theory study explored women’s decision-making processes in their treatment for ESBC, and elucidated the role of the surgeon and the practice environment in the increasing rates. The Health-Belief Model was applied, discerning those factors influential in surgical decision-making shaping women’s choice for UM+/-CPM. Design: Semi-structured interviews were conducted with patients to understand their experiences and decision-making which resulted in undergoing UM+/-CPM. Similarly, semi-structured interviews were conducted with general surgeons exploring their treatment approaches to ESBC. Theoretical sampling identified suitable candidates. Data were collected until saturation was reached. Constant comparative analysis identified key concepts.
The Rotor Position Estimation Error Improved Method for Sensorless Starting Control of Brushless Synchronous Machine

This article proposed a sensorless starting control method for the brushless synchronous machine with the indirectly injected high-frequency signal, where the high-frequency signals are injected into the stator windings of the main exciter instead of the main generator. The impact of the nonlinear links of the rotary rectifier and various filters on the rotor position estimation error during the asynchronous demodulation method is analyzed in detail. Since the phase delay of the bandpass filter and the low-pass filter will deteriorate the zero-crossing points of the envelope curve, the signal restoration module could not restore the sinusoidal envelope curve accurately, then, the estimated rotor position error is expanded with the increasing of rotor speed in the starting process. Therefore, a novel mathematical analysis method with fewer filters for the rotor position demodulation is presented to improve the estimated rotor position error compared to the traditional method, and the feasibility and effectiveness of the proposed method are verified by the comparison of the simulation and experimental results.
Post-Craniotomy Pain in the Brain Tumor Patient: An Integrative Review

Context. Patients with brain tumors undergo craniotomies, but craniotomies have been widely believed to be less painful than other surgical procedures. Understanding the experience of postcraniotomy pain will help guide patient care, future research and policy development. Objective. This integrative review examined prevalence, influencing factors, associated symptom clusters, and consequences of post-craniotomy, post-brain tumor pain. Methods. A literature search was conducted utilizing Medline, OVID, PubMed and CINAHL using key words “traumatic brain injury,” “pain, post-operative,” “brain injuries,” “postoperative pain,” “craniotomy,” “decompressive craniectomy,” and “trephining. ” The Theory of Unpleasant Symptoms (TOUS) was used as a guide for abstracting information from each article, including: influencing factors, associated symptom clusters, and consequences of postcraniotomy, post-brain tumor pain. Inclusion criteria were indexed, peer-reviewed, full-length, English-language articles. Results. The search yielded 115 articles, with 24 meeting inclusion criteria. Hand-searching yielded an additional 2 articles, for a total of 26 articles reviewed. Most studies reviewed (88%) were randomized, controlled trials conducted outside of the United States, and tested pharmacological pain therapies. Although all articles documented the existence of postcraniotomy, post-brain tumor pain, only 12 each discussed influencing factors and associated symptom clusters and 15 reviewed patient performance, while two included information on all four aspects. Conclusion. The TOUS was helpful in providing structure to our search and can be used to study post-craniotomy, post-brain tumor pain. Further research is needed to improve our understanding and management of post-craniotomy, post-brain tumor pain. Running head: POST-CRANIOTOMY TUMOR PAIN 3
Divisia Monetary Aggregates for Developing Economies: Some Theory

Asset market development is characterized by reducing market imperfections that generate costs incurred from participating in the financial system. In developing economies where financial markets are nascent, these costs are likely to be binding. This limits the typical economic agent's ability to fully access asset market, inducing partial access. In this note, we embed financial market imperfections into the Divisia aggregate-theoretic literature and illustrate their relevance in the derivation of user cost of money and consequently, Divisia monetary aggregates. Asset market imperfections are introduced through endogenous portfolio adjustment costs that proxy for, among other things, informational, transactional, liquidity, and portfolio management costs. The presence of adjustment costs induce additional costs that alter the standard user cost of money. We show that the user cost that arises from our model can be practically implemented in the construction of Divisia aggregates as in the standard Barnett (1978) user cost.
INFANT ADIPOSITY IS INFLUENCED BY THE MATERNAL NUTRITION

The evidence has shown that maternal nutrition is related with infant body composition and an increased risk of obesity and chronic diseases in adulthood. The nutritional status at pre-pregnancy, the excessive gestational weight gain, inadequate intake of nutrients and excess of energy during gestation, as well as the rapid weight gain during the first two years of life, are some of the factors related with the disturbance of the body composition and the adiposity in the pediatric age. This article traces the origins of infant adiposity back to pregnancy and preconception periods.
A Review of Problem Solving and Reflection as Caregiver Coaching Strategies in Early Intervention

An increasing number of researchers are examining the benefits and outcomes of caregiver-implemented interventions for young children with delays or disabilities. Most report the incorporation of multiple coaching strategies within their approach; however, definitions and descriptions of coaching strategies and processes continue to be limited. This scoping review examined the use of various coaching strategies across models of caregiver coaching in early intervention, with a specific focus on problem solving and reflection coaching strategies occurring in the literature between 2011 and 2018. Problem solving and reflection are 2 coaching strategies incorporated into coaching approaches to build caregiver competency, confidence, and independence within intervention implementation. The results of this review may guide the field in further defining caregiver coaching as well as specific coaching strategies, such as problem solving and reflection.
Correlation of age and gender with different histological subtypes of primary lung cancer

Background: Histological subtypes of lung carcinoma vary between gender and age groups. Younger age group has more predilections for adenocarcinoma (ACC) while squamous cell carcinoma (SCC) is more common in older age group. Gender wise, ACC is more frequent among females as compare to males. Aim: Present study analysed the distribution of histological subtypes among different age groups (younger vs. older) and gender (male vs. females) to find out predominance of any particular subtype or a specific pattern relating to age and gender in Indian population. Materials and Methods: Data of 342 patients were retrospectively analysed in terms of age, gender and pathological diagnosis. The patients were grouped into two, younger age group (≤50 years) and older age group (>50 years). Results: There were 280 (81.87%) male and 62 (18.12%) female patients. Male:female ratio was 4:51. There were 134 patients (39.18%) in younger age group and 208 (60.81%) patients in older age group. Majority of the patients (272) were nonsmall cell lung carcinoma (NSCLC) (79.53%) while 70 patients had small cell lung carcinoma (20.46%). Out of 272 patients with NSCLC, 130 (38%), were SCC, 92 (26.90%) patients had ACC and rest 50 (14.61%) patients were of large cell lung carcinoma. No significant predilection for a particular histological subtype in younger and older age group was observed. In males SCC was the most common subtype (42.14%, P = 0.0014) and in females ACC was most frequent (48.38%, P = 0.0001). Conclusion: Squamous cell carcinoma in males, ACC in females and overall SCC is the most common histological subtype. No significant correlation with age was found.
Isolation and Characterization of Two Microalgal Isolates from Vietnam with Potential for Food, Feed, and Biodiesel Production

Microalgae are promising feedstock for the production of biodiesel and diverse medium- and high-value products such as pigments and polyunsaturated fatty acids. The importance of strain selection adapted to specific environments is important for economical purposes. We characterize here two microalgal strains, isolated from wastewater of shrimp cultivation ponds in Vietnam. Based on the 18S rDNA-ITS region, one strain belongs to the Eustigmatophyceae class and is identical to the Nannochloropsis salina isolate D12 (JX185299.1), while the other is a Chlorophyceae belonging to the Desmodesmus genus, which possesses a S516 group I intron in its 18S rDNA gene. The N. salina strain is a marine and oleaginous microalga (40% of dry weight (DW) at stationary phase) whole oil is rich in saturated fatty acids (around 45% of C16:0) suitable for biodiesel and contains a few percent of eicosapentaenoic acid (C20:5). The Desmodesmus isolate can assimilate acetate and ammonium and is rich in lutein. Its oil contains around 40%–50% α-linolenic acid (C18:3), an essential fatty acid. Since they tolerate various salinities (10% to 35‰), both strains are thus interesting for biodiesel or aquaculture valorization in coastal and tropical climate where water, nutrient, and salinity availability vary greatly depending on the season.
Can RSV-Associated Hospitalization in the First Year of Life be Predicted at Birth Among Infants Born at 32-35 Weeks Gestation?

xi LIST OF ABBREVIATIONS AND SYMBOLS USED . xii ACKNOWLEDGEMENTS . xiv CHAPTER 1: INTRODUCTION . 1 CHAPTER 2: BACKGROUND . 5 2.1 EPIDEMIOLOGY OF RESPIRATORY SYNCYTIAL VIRUS . 5 2.2 POPULATIONS AT HIGHEST RISK FOR RSV-ASSOCIATED SEVERE LOWER RESPIRATORY TRACT INFECTION . 6 2.3 PREVENTION OF RESPIRATORY SYNCYTIAL VIRUS . 8 2.4 RISK FACTORS ASSOCIATED WITH RSV-ASSOCIATED HOSPITALIZATION IN PREMATURE INFANTS . 8 2.5 DEVELOPMENT AND VALIDATION OF RISK SCORING TOOLS TO PREDICT RSVASSOCIATED HOSPITALIZATION . 11 CHAPTER 3: OBJECTIVES . 17 CHAPTER 4: METHODOLOGY . 18 4.1 OVERVIEW OF STUDY DESIGN AND ETHICS . 18 4.1. 1 Inclusion and Exclusion Criteria . 19 4.1. 2 Defining Gestational Age . 19 4.1. 3 Study Outcome-RSV-Associated Hospitalization . 19 4.1. 4 Predictive Variables.20 4.2 DATA SOURCES . 26 4.2.1 Reproductive Care Program (RCP)-The Nova Scotia Atlee Perinatal Database (NSAPD) . 26
Physicochemical characteristics of poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) electrospun nanofibres for the adsorption of phenol

Abstract In this study, adsorption treatment of phenol pollutant using electrospun poly(3-hydroxybutyrate) [P(3HB)] and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) [P(3HB-co-3HHx)] is highlighted for the first time. Both P(3HB) and P(3HB-co-3HHx) were extracted from bacterial cells and nanofibres were fabricated through electrospinning technique for the adsorption of phenol. The electrospun nanofibres were optimised after preliminary study of the electrospinning parameters (i.e. applying different voltages, polymer concentrations and mixed solvent ratios). The effects of adsorption under different variables such as contact of time, pH, initial concentration and temperature were studied. The raw polymers were characterised with gas chromatography (GC), gas permeation chromatography (GPC) while the electrospun fibres were investigated using thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and viewed under field emission scanning electron microscope (FESEM). P(3HB) had higher molecular weight as well as higher crystallinity and thermal stability than P(3HB-co-3HHx). The maximum phenol adsorption capacity of optimised nanofibre with weight of 0.14 g was 35.7 mg/g. The adsorption trend of the isotherm followed the Freundlich (R 2 = 0.99) and adsorption kinetics of pseudo-second-order. The equilibrium contact time was 10 min with 99.8% of the phenol removed and attained 99.9% removal after optimal contact time of 270 min for all samples. This innocuous product has strong affinity towards organic pollutants and zero by-products were produced after the adsorption.
The Impacts of Selling Expense Structure on Enterprise Growth in Large Enterprises: A Study from Vietnam

This study intends to examine the impact of selling expense structure on the business growth of 255 Vietnamese large-scale enterprises in three different industries (Consumer Staples, Industrials, and Manufacture) listed on the Vietnamese Stock Exchange over four years from 2015 to 2018. By using STATA software (StataCorp LLC, 4905 Lakeway Drive, College Station, Texas 77845-4512, USA), the research outcomes indicate that both labour expense and depreciation expense have a negative influence on revenue growth and firm size growth but positive influence on profit growth while materials and tools expenses negatively affect all three dependent variables. Furthermore, an increase in the proportion of outsourcing expenses and other selling expenses would result in a significant increase in revenue but a decline in the profit of these companies. From this research results, large-scale enterprises should consider changing the selling expense structure as they spend too much on outsourcing and other selling expenses (60%–70% total selling expense) but too little on labour, which plays an important role in upgrading the profitability of these enterprises.
The effect of generalist-specialist integration on physician behavior, medical outcomes, and medical care spending

I study the effects of integration among generalist and specialist physicians on referral and treatment choices, inpatient admissions, and the cost of medical care. I first construct a novel data set that links the structure of physician organizations to physician behavior for two groups of individuals deemed most likely to benefit from generalist-specialist integration: individuals diagnosed with hypertension and diabetes mellitus. Due to differential selection across integrated and non-integrated practices, ordinary least squares regression is unlikely to identify the effects of interest. To surmount the identification problem, I simulate random assignment of beneficiaries to physician organizations in an instrumental variables framework. My estimates confirm that integration among generalist and specialists significantly affects referral decisions and treatment patterns. I fail to detect evidence that this kind of integration improves medical outcomes or reduces medical care spending. These findings strongly suggest that policies increasing generalist-specialist integration in piece-rate or fee-for-service environments are unlikely to achieve their goals. Finally, I consider the theoretical literature that might rationalize generalist-specialist integration patterns. I show that most potential explanations are inconsistent with my evidence, save for David and Neuman (2011), suggesting that task adhesion should be a focal point for future research. Degree Type Dissertation Degree Name Doctor of Philosophy (PhD) Graduate Group Health Care Management & Economics This dissertation is available at ScholarlyCommons: http://repository.upenn. edu/edissertations/1958 First Advisor Guy David Second Advisor Robert J. Town
Mechanical properties of hydrogenated amorphous silicon (a-Si:H) particles

A nanoindenter was used to compress individual particles of hydrogenated amorphous silicon (a-Si:H) ranging in diameter from 290 nm to 780 nm. The colloidal synthesis used to produce the particles enables the hydrogen content to be manipulated over a wide range, from about 5 at. % to 50 at. %, making these a-Si:H particles promising for applications in lithium ion batteries, hydrogen storage, and optical metamaterials. Force-displacement curves generated using a tungsten probe flattened with focused ion beam exhibited elastic and then plastic deformations, followed by fracture and crushing of the particles. For particles with 5% and 50% H, Young's moduli, yield strengths, and compressive strengths were 73.5(±19.5) GPa, 5.8 GPa, and 3.2(±0.1)–9.3(±0.6) GPa and 31.2(±9.0) GPa, 2.5 GPa, and 1.8 (±0.3)–5.3(±0.8) GPa, respectively. Particles with more hydrogen were significantly more compliant and weaker. This is consistent with atomistically detailed molecular dynamics simulations, which revealed compression forms of an interphase of H atom clusters that weakens the material.A nanoindenter was used to compress individual particles of hydrogenated amorphous silicon (a-Si:H) ranging in diameter from 290 nm to 780 nm. The colloidal synthesis used to produce the particles enables the hydrogen content to be manipulated over a wide range, from about 5 at. % to 50 at. %, making these a-Si:H particles promising for applications in lithium ion batteries, hydrogen storage, and optical metamaterials. Force-displacement curves generated using a tungsten probe flattened with focused ion beam exhibited elastic and then plastic deformations, followed by fracture and crushing of the particles. For particles with 5% and 50% H, Young's moduli, yield strengths, and compressive strengths were 73.5(±19.5) GPa, 5.8 GPa, and 3.2(±0.1)–9.3(±0.6) GPa and 31.2(±9.0) GPa, 2.5 GPa, and 1.8 (±0.3)–5.3(±0.8) GPa, respectively. Particles with more hydrogen were significantly more compliant and weaker. This is consistent with atomistically detailed molecular dynamics simulations, which revealed compression .
Transcriptome sequencing and screening of genes related to sex determination of Trichosanthes kirilowii Maxim

Trichosanthes kirilowii Maxim. (TK) is a dioecious plant in the Cucurbitaceae for which different sexes have separate medicinal uses. In order to study the genes related to sex determination, transcriptome sequencing was performed on flower buds of male and female plants using the high-throughput sequencing technology. A total of 145,975 unigenes and 7110 DEGs were obtained. There were 6776 DEGs annotated to 1234 GO terms and enriched to 18 functional groups, including five biological processes related to sugar metabolism. KEGG pathway analysis indicated genes involved in hormone transduction, hormone synthesis and carbohydrate metabolism. Many DEGs of TK are involved in reproductive organ formation, hormone signal transduction and regulatory networks. Combining the results of GO, KEGG and qRT-PCR, 11 sex determining candidate genes of TK were selected, including MYB80, MYB108, CER1, CBL9, ABCB19, SERK1, HSP81-3, ACS9, SEP3, AUX1 and YUC6. The results provide a foundation for the study of sex differentiation in TK.
Links between Pharmaceutical R&D Models and Access to Affordable Medicines

Each patient in the European Union has a right of access to care. National governments face the challenge to balance resources against healthcare demand to ensure that populations enjoy equitable access to effective, affordable and sustainable healthcare. This study describes the main challenges with regard to access to affordable medicines, including Research & Development, pricing and reimbursement of medicines and the influence of the economic crisis. Potential policy options to tackle these challenges are presented, drawing on best practices and a review of specific measures implemented in different European countries. This document was provided by Policy Department A for the Committee on the Environment, Public Health and Food Safety.