Miracle-dz/UniFAR-FTUs huggingface dataset:
Multifunctional 25D metastructures enabled by adjoint optimization

Optical metasurfaces are two-dimensional arrays of meta-atoms that modify different characteristics of light such as phase, amplitude, and polarization. One intriguing feature that distinguishes them from conventional optical components is their multifunctional capability. However, multifunctional metasurfaces with efficiencies approaching those of their single-functional counterparts require more degrees of freedom. Here we show that 2.5D metastructures, which are stacked layers of interacting metasurface layers, provide sufficient degrees of freedom to implement efficient multifunctional devices. The large number of design parameters and their intricate intercoupling make the design of multifunctional 2.5D metastructures a complex task, and unit-cell approaches to metasurface design produce suboptimal devices. We address this issue by designing 2.5D metastructures using the adjoint optimization technique. Instead of designing unit cells individually, our technique considers the structure as a whole, accurately accounting for inter-post and inter-layer coupling. As proof of concept, we experimentally demonstrate a double-wavelength metastructure, designed using adjoint optimization, that has significantly higher efficiencies than a similar device designed with a simplified approach conventionally used in metasurface design. The 2.5D metastructure architecture empowered by the optimization-based design technique is a general platform for realizing high-performance multifunctional components and systems.
Candidemia in cancer and bone marrow transplant patients: A 10-year retrospective analysis

In cancer and bone marrow transplant patients, a number of studies have documented a shift in recent years in the species that cause candidemia. While Candida albicans was formerly the predominant species cultured, fluconazole-resistant species, particularly Candida glabrata and Candida krusei, have become more common. In our center, we reviewed 247 blood culture results that were positive for Candida, comparing results during a period of low prophylactic fluconazole use and a period of higher fluconazole use. Overall, there was a significant decrease in C albicans isolates and a corresponding significant increase in non-albicans isolates from the first period to the second. We discuss the extent to which these findings can be attributed directly to the prophylactic use of fluconazole.
Predictors of itch and pain in the 12 months following burn injury: results from the Burns Registry of Australia and New Zealand (BRANZ) Long-Term Outcomes Project

Abstract Background Itch and pain are common complaints of patients with burn injuries. This study aimed to describe the prevalence and predictors of itch and moderate to severe pain in the first 12 months following a burn injury, and determine the association between itch, moderate to severe pain, work-related outcomes, and health-related quality of life following a burn injury. Methods Burn patients aged 18 years and older were recruited from five Australian specialist burn units. Patients completed the 36-item Short Form Health Survey Version 2 (SF-36 V2), the Sickness Impact Profile (SIP) work scale, and a specially developed questionnaire relating to itch at 1, 6, and 12 months post-injury. Moderate to severe pain was defined as a score less than 40 on the bodily pain domain of the SF-36 V2. Multivariate mixed-effects regression models were used to identify patient and burn injury predictors of itch and moderate to severe pain. Results Three hundred and twenty-eight patients were included. The prevalence of itch decreased from 50% at 1 month to 27% at 12 months. Similarly, the prevalence of moderate to severe pain decreased from 23% at 1 month to 13% at 12 months. Compared to patients aged 18-34, the adjusted odds of experiencing any itch were 59% (95% CI: 0.20, 0.82) and 55% (95% CI: 0.22, 0.91) lower for patients aged between 35 and 49 and ≥ 50 years, respectively. Compared to patients aged 18-34, the adjusted odds of experiencing moderate to severe pain were 3.12 (95% CI: 1.35, 7.20) and 3.42 (95% CI: 1.47, 7.93) times higher for patients aged 35-49 and ≥ 50 years, respectively. Conclusions Less than 15% of patients reported moderate or severe pain at 12 months, while approximately one-quarter of the patients reported itch at the same period. The presence of moderate to severe pain was associated with a greater negative impact on health-related quality of life and work outcomes compared to itch. Further research is needed to improve our ability to identify patients at higher risk of persistent itch and pain who would benefit from targeted review and intervention studies.
ANALISIS OPTIMALISASI FUNGSI BALL JOINT PADA MESIN UJI TARIK DENGAN MENGGUNAKAN FEM

Provision of teaching aids for learning is a matter that is needed by academics, such as the tensile testing machine. Tensile testing machine consists of several components, including: Frame, power transfer screw, pulling throttle, fixed grip holder, cross head, pulling screw pair, power screw gear, drive gear, WPX gear box, chain, v-belt, driving pulley, electric motor, sprocket, WPA gearbox, drived pulley. With the tensile testing machine, academics know the characteristics of the material, as an important knowledge of material materials viewed from materials that have tensile strength, compressive strength, twisting force, shear force, modulus of elasticity, to where the material is already unable to withstand the load and break up (Fracture / Break). From the research results obtained a maximum load of 292 MPa far exceeds the yield stress of AISI 1035 material of 282.69 MPa, for Savety of Factor obtained 0.97 is also below the safety factor standard of 1.
Comparison of haemodynamic parameters in two different geriatric age groups undergoing cemented bipolar hemiarthroplasty

Background: To conduct a prospective observational study to compare the haemodynamic changes in two age groups, group A: 60-75yrs and group B: >75yrs during cemented bipolar hemiarthroplasty for hip fractures under spinal anaesthesia. Methods: Patients of either sex belonging to above two groups, with no contra-indications for central neuraxial block received spinal anesthesia at lumbar level. Heart Rate (HR), Systolic Blood Pressure(SBP), Diastolic Blood Pressure(DBP) and Mean Arterial Pressure(MAP), pulse pressure variability(PPV), arterial oxygen saturation (SpO2), Electrocardiogram for any changes and nasal end tidal CO2 (EtCO2) were recorded at the following time points: baseline(on table), after giving spinal, after giving surgical position, at the start of surgery, at femoral canal reaming, immediately after cement insertion, every 2 minutes after cement insertion, femoral joint reduction and the end of the surgery. Hypotension, bradycardia, arrythmias, desaturation or unexpected loss of consciousness occurring in pericementation period suggestive of ‘Bone cement implantation syndrome’(BCIS) or any other adverse event was recognized and treated. Results: The SBP, HR, PPV, ETCO2, SPO2 and incidence of adverse events; were comparable in both the groups. The difference in the DBP and MAP was statistically significant. Conclusions: The difference in the occurrence of haemodynamic alterations was more in the older age group. Continuous vigilant monitoring during bipolar hemiarthroplasty is required.
An Algebraic Multigrid Method for Eigenvalue Problems in Some Different Cases

The aim of this paper is to develop an algebraic multigrid method to solve eigenvalue problems based on the combination of the multilevel correction scheme and the algebraic multigrid method for linear equations. Our approach uses the algebraic multigrid method setup procedure to construct the hierarchy and the intergrid transfer operators. In this algebraic multigrid scheme, a large scale eigenvalue problem is solved by some algebraic multigrid smoothing steps in the hierarchy and very small-dimensional eigenvalue problems. To emphasize the efficiency and flexibility of the proposed method, here we consider a set of test eigenvalue problems, discretized on unstructured meshes, with different shape of domain, singularity, and discontinuous parameters. Moreover, global convergence independent of the number of desired eigenvalues is obtained.
Reflections on a Decade of Promoting Consumer Health Resources at Remote Area Medical Clinics

Abstract Librarians at the East Tennessee State University (ETSU) Quillen College of Medicine Library have provided consumer health outreach services to rural and underserved populations at Remote Area Medical (RAM) clinics since 2009. These outreach services heavily depend upon and promote consumer health websites and National Library of Medicine (NLM) resources in order to reach the largest number of people at the lowest possible cost. This article will provide a brief overview of RAM clinics in Wise, VA, and Gray, TN, served by ETSU librarians for years. Additionally, this article will discuss the evolution of ETSU QCoM librarian outreach initiatives relating to these clinics over the past decade. This article includes a list of online consumer health resources used to support these initiatives as well as a list of most commonly addressed consumer health topics.
Practical application of a safe human-robot interaction software

Purpose Because of the increased use of robots in the industry, it has become inevitable for humans and robots to be able to work together. Therefore, human security has become the primary noncompromising factor of joint human and robot operations. For this reason, the purpose of this study was to develop a safe human-robot interaction software based on vision and touch. Design/methodology/approach The software consists of three modules. Firstly, the vision module has two tasks: to determine whether there is a human presence and to measure the distance between the robot and the human within the robot’s working space using convolutional neural networks (CNNs) and depth sensors. Secondly, the touch detection module perceives whether or not a human physically touches the robot within the same work environment using robot axis torques, wavelet packet decomposition algorithm and CNN. Lastly, the robot’s operating speed is adjusted according to hazard levels came from vision and touch module using the robot’s control module. Findings The developed software was tested with an industrial robot manipulator and successful results were obtained with minimal error. Practical implications The success of the developed algorithm was demonstrated in the current study and the algorithm can be used in other industrial robots for safety. Originality/value In this study, a new and practical safety algorithm is proposed and the health of people working with industrial robots is guaranteed.
New Canonical and Grand Canonical Density of States Techniques for Finite Density Lattice QCD

We discuss two new density of states approaches for finite density lattice QCD (Quantum Chromo Dynamics). The paper extends a recent presentation of the new techniques based on Wilson fermions, while here, we now discuss and test the case of finite density QCD with staggered fermions. The first of our two approaches is based on the canonical formulation where observables at a fixed net quark number N are obtained as Fourier moments of the vacuum expectation values at imaginary chemical potential θ . We treat the latter as densities that can be computed with the recently developed functional fit approach. The second method is based on a direct grand canonical evaluation after rewriting the QCD partition sum in terms of a suitable pseudo-fermion representation. In this form, the imaginary part of the pseudo-fermion action can be identified and the corresponding density may again be computed with the functional fit approach. We develop the details of the two approaches and discuss some exploratory first tests for the case of free fermions where reference results for assessing the new techniques may be obtained from Fourier transformation.
Surveillance of Respiratory Viral Healthcare associated infections (rHAI) amongst inpatients in selected Hospitals in Kenya

xviii Chapter one . 1 1.0 Introduction . 1 1.1 Background information . 1 1.2 Justification of the study . 3 1.3 Statement of the problem . 4 1.4 Research question(s) . 6 1.5 Study objectives . 6 1.5. 1 General objective . 6 1.5. 2 Specific objectives. 7 Chapter two . 8 2.0 Literature review . 8 2.1 Healthcare associated infections (HAI) . 8 2.2 The burden of hai . 8 2.3 The aetiology of healthcare associated infections (HAI) . 10 2.4 Patient susceptibility to healthcare-associated infections11 2.5 Environmental factors associated with HAI . 12 2.6 Global impact of HAI. 12 2.7 Respiratory viral healthcare associated infections . 14
Sketch Fewer to Recognize More by Learning a Co-Regularized Sparse Representation

Categorizing free-hand human sketches has profound implications in applications such as human computer interaction and image retrieval. The task is non-trivial due to the iconic nature of sketches, signified by large variances in both appearance and structure when compared with photographs. Despite recent advances made by deep learning methods, the requirement of a large training set is commonly imposed making them impractical for real-world applications where training sketches are cumbersome to obtain – sketches have to be hand-drawn one by one other than crawled freely on the Internet. In this work, we aim to delve further into the data scarcity problem of sketch-related research, by proposing a few-shot sketch classification framework. The model is based on a co-regularized embedding algorithm where common/shareable parts of learned human sketches are exploited, thereby can embed query sketch into a co-regularized sparse representation space for few-shot classification. A new dataset of 8,000 part-level annotated sketches of 100 categories is also proposed to facilitate future research. Experiment shows that our approach can achieve an 5-way one-shot classification accuracy of 85%, and 20-way one-shot at 51%.
Trend analysis of sea level changes using IBM SPSS software

ABSTRACT In this study, trend analysis of the sea level observations was made by using data from Sinop and Antalya tide gauge stations in Turkey. The aforementioned data were downloaded as free from the General Command of Mapping website by using the web portal of Turkish National Sea Level. Hourly data gathered between 17th November 1998 and 15th January 2018 from Antalya tide gauge station were used. Data with 15-minute intervals between 18th June 2005 and 25th October 2016 were used in Sinop tide gauge station. Sea level data provided by the portal of Turkish National Sea Level were gathered using local datum of the stations. Trend analysis of the sea level observations was made by assessing the downloaded data using SPSS 16.0 package software. In determination of trend presence, simple linear regression analysis was used in addition to nonparametric tests Kendall's tau-b and Spearman's Rho.
Multicomponet Synthesis of Pyrrolo [3,4-a] Carbazole-1,3-Diones

Pyrrolocarbazoles are important structural motives present in many natural products and pharmaceuticals. Particularly, pyrrolo [3,4-a] carbazole-1,3-diones have attracted much attention as analogues of bioactive compounds, such as anticancer agent granulatimide. Surprisingly, only a few methods for the synthesis of these compounds have been reported in the literature, and they are almost limited to the Diel–Alder cycloaddition of 3-vinylindoles. We have recently developed a multicomponent synthesis of polysubstituted anilines starting from ,-unsaturated carbonyls, isocyanides and dienophiles. Here we report the application of this tandem [4 + 1]–[4 + 2] cycloaddition procedure for the synthesis of 4-amino-5-arylisoindoline-1,3-diones, which are then cyclized by means of a metal catalyzed intramolecular C-N coupling, affording structurally diverse, natural product-like pyrrolo [3,4-a] carbazole-1,3-diones with high yields and selectivities.
Diseño de sistema experto para búsqueda de plazas libres en un aparcamiento mediante aprendizaje automático y visión artificial

Encontrar sitios libres en aparcamientos dedicados es un problema cotidiano al que se enfrentan los conductores. Debido a la falta de conocimiento de la situacion exacta de las posiciones libres dentro de los aparcamientos, pierden una cantidad de tiempo innecesario en la busqueda de huecos en los que poder aparcar. Un sistema capaz de estimar las caracteristicas del vehiculo a estacionar y de ubicar los huecos libres validos para el tamano de ese vehiculo, disminuiria los tiempos de busqueda empleados por los conductores y conseguiria un reparto optimo de las plazas del aparcamiento. El sistema propuesto combina tecnicas de inteligencia artificial, para determinar la ocupacion y distribucion de los vehiculos dentro del aparcamiento, y de entornos distribuidos, para optimizar los computos y escalabilidad del sistema. Mediante tecnicas de vision artificial y redes neuronales el sistema implementa los modulos necesarios para la deteccion de vehiculos dentro de un aparcamiento. Primero, el sistema genera un mapa computacional con las posiciones y tamanos de las plazas de aparcamientos. Segundo, identifica las caracteristicas de los vehiculos entrantes empleando tecnicas de vision por computador para establecer las medidas. Tercero, identifica y diferencia los vehiculos de otros objetos dentro del aparcamiento para conocer su ubicacion exacta y tamano empleando redes neuronales. Finalmente, el sistema identifica a los vehiculos entrantes asignandoles la ubicacion optima en funcion de sus caracteristicas, gracias al conocimiento de la ocupacion del aparcamiento en tiempo real. Se evalua la precision del sistema obteniendo resultados en la de deteccion de la ocupacion del 93,39%, lo que indica el gran potencial del sistema como mejora a los enfoques actuales basados en la deteccion de aparcamiento en recintos exteriores mediante inteligencia artificial, proponiendo nuevos enfoques y caracteristicas no estudiadas hasta el momento.
The Problem with Solutions: Development Failures in Bangladesh and the Interests They Obscure

Long described as the “largest poorest” country, Bangladesh has been a prime target for massive infusions of foreign aid for decades. Through historical and ethnographic investigation, I document how flood control and agricultural intensification projects underwritten by foreign institutions exacerbate vulnerability to water crises in Bangladesh. These ostensibly pro-poor water governance and economic development programs engender cycles of crop loss, groundwater and soil salinization, reduced fisheries, and impeded navigation that erode agrarian livelihoods, thereby reproducing the conditions and rationale for continued flows of aid dollars into the country. Shifting attention away from depoliticized problems and solutions, I develop the concept of the interest-shed as a broadly applicable method for intervening in cycles of failure by examining the interests that they serve. This framework can also be used in the planning process by enabling differently situated groups to evaluate how proposed schemes include, ignore, or prioritize their interests.
A “BOA COMBINAÇÃO” ENTRE GÊNERO E SOCIOLOGIA ECONÔMICA: UMA (RE)LEITURA DOS MERCADOS INSPIRADA EM VIVIANA ZELIZER

A sociologia economica, apos a decada de 1990, tem se aberto para novas frentes de investigacao, sendo uma delas o genero. Apesar dessa abertura, Richard Swedberg afirmou, em artigo de 2004, que havia uma ‘lacuna’ historica no tratamento dos temas de genero em sociologia economica. Essa tese foi corroborada na ocasiao por Viviana Zelizer, para quem a Sociologia dos fenomenos economicos tem centrado seu escopo de analise em temas institucionais, excluindo qualquer analise de genero. Em dialogo com essas teses, o artigo busca um primeiro mapeamento sobre os estudos recentes feitos por sociologos da economia no Brasil, os quais tocam na questao de genero. A metodologia aplicada foi o levantamento lexicografico na base de dados da SciELO entre 1997-2019, por meio do termo “sociologia economica”. Os resultados indicam a centralidade de Zelizer nesta agenda de pesquisa e um avanco consideravel no tema; contudo, quando relacionado com os temas de pesquisa mais mainstream, a tematica genero continua como um tema nao convencional.
Pharmacogénétique de la clozapine et intérêt de l’association avec la fluvoxamine

La clozapine (CLZ) est le traitement de reference de la schizophrenie pharmaco-resistante, mais avec une absence de reponse chez 30 a 40% des patients. Elle est metabolisee a 70% par le CYP1A2 en N-desmethylclozapine (DMC). Un rapport CLZ/DMC eleve serait associe a une meilleure tolerance. Le polymorphisme genetique CYP1A2*1F (present a 68% dans la population caucasienne) entraine une augmentation de l’activite enzymatique. A l’etat homozygote il serait associe a une moins bonne reponse a la clozapine, surtout chez les fumeurs. La fluvoxamine est un antidepresseur inhibiteur de la recapture de serotonine ayant une action inhibitrice du CYP1A2. L’Unite pour Malades Difficiles du Centre Hospitalier du Rouvray accueille plusieurs patients atteints de schizophrenie pharmaco-resistante et fumeurs. Le genotypage du CYP1A2 n’a pas permis d’associer le genotype CYP1A2*1F/*1F a la resistance a la clozapine. Il a ete constate chez ces patients une correlation entre la diminution du rapport CLZ/DMC et la consommation de tabac, de facon dose-dependante. L’association a la fluvoxamine etait correlee a une augmentation dose-dependante des rapports Concentration/Dose en clozapine et CLZ/DMC. Une evolution defavorable de la tolerance globale etait correlee a la clozapinemie chez les patients homozygotes CYP1A2*1F/*1F. L’intensite de la sedation etait positivement correlee au rapport CLZ/DMC. La pharmacogenetique de la clozapine et son association a la fluvoxamine s’integrent dans une approche de medecine personnalisee, afin d’individualiser le traitement des patients atteints de schizophrenie resistante, et ainsi de favoriser l’efficacite et de limiter les effets secondaires.
Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates

Host-virus arms races are inherently asymmetric; viruses evolve much more rapidly than host genomes. Thus, there is high interest in discovering mechanisms by which host genomes keep pace with rapidly evolving viruses. One family of restriction factors, the APOBEC3 (A3) cytidine deaminases, has undergone positive selection and expansion via segmental gene duplication and recombination. Here, we show that new copies of A3 genes have also been created in primates by reverse transcriptase-encoding elements like LINE-1 or endogenous retroviruses via a process termed retrocopying. First, we discovered that all simian primate genomes retain the remnants of an ancient A3 retrocopy: A3I. Furthermore, we found that some New World monkeys encode up to ten additional APOBEC3G (A3G) retrocopies. Some of these A3G retrocopies are transcribed in a variety of tissues and able to restrict retroviruses. Our findings suggest that host genomes co-opt retroelement activity in the germline to create new host restriction factors as another means to keep pace with the rapid evolution of viruses. (163)