Miracle-dz/UniFAR-FTUs huggingface dataset:
Structure and function of the kidney

The kidneys are the archetypal organs of homeostasis. Their primary function is filtration and segregation. Through these processes they rebalance the continual electrolyte and chemical disturbances that derive from physiological and pathological metabolic processes. Electrolytes, hydrogen (H+) ions from metabolic acids, amino acids, fatty acids, plasma proteins, immunoglobulins, and metabolic products are either retained, reabsorbed, and recycled; or they are filtered, secreted, concentrated, and excreted. These processes convert approximately 120 ml/min of primary glomerular filtrate into 1 ml/min of urine. In addition, the kidneys play crucial roles in bone mineralization, the maintenance of cardiovascular tone, systemic blood pressure, and bone marrow synthetic function via their contribution to vitamin D production, the renin–angiotensin system, and erythropoiesis.
Predictor‐based adaptive feedback control for a class of systems with time delay and its application to an aircraft skin inspection robot

This study presents a predictor-based adaptive feedback control for a class of systems with a known input time delay, an arbitrary large unknown output time delay, unmeasurable states, unmodelled dynamics and disturbances. First, a predictor is employed to cope with the input time delay, and an input delay-free system was established. Then, to overcome the arbitrarily large unknown output time delay and unmeasurable states, an augmented descriptor observer is developed for the new delay-free system. Finally, an adaptive neural network is constructed to estimate the lumped unknown term by backstepping control and obtain the preliminary estimated model, which can compensate the unknown dynamic disturbances and the unmodelled dynamics in the backstepping iteration to achieve the desired tracking performance. In addition, to demonstrate the efficiency of the proposed scheme, the control of pressure difference is also implemented in the adsorption system of an aircraft skin inspection robot, and the simulation results verify the feasibility and effectiveness of the proposed control scheme.
New and Enhanced Tools for Civil Military Operations (NET-CMO)

Civil Military Operations (CMO) associated geospatial modeling is intended to enable increased knowledge of regional stability, assist in Foreign Humanitarian Assistance (FHA), and provide support to Force Health Protection (FHP) operational planning tasks. However, current geoenabled methodologies and technologies are lacking in their overall capacity to support complex mission analysis efforts focused on understanding these important stability factors and mitigating threats to Army soldiers and civilian populations. CMO analysts, planners, and decision-makers do not have a robust capability to both spatially and quantitatively identify Regions of Interest (ROI), which may experience a proliferation in health risks such as vector-borne diseases in areas of future conflict. Additionally, due to this general absence of geoenabled health assessment models and derived end-products, CMO stakeholders are adversely impacted in their Military Decision Making Process (MDMP) capabilities to develop comprehensive area studies and plans such as Course of Action (COA). The NET-CMO project is focused on fostering emerging geoenabling capabilities and technologies to improve military situational awareness for assessment and planning of potential health threat-risk vulnerabilities. DISCLAIMER: The contents of this report are not to be used for advertising, publication, or promotional purposes. Citation of trade names does not constitute an official endorsement or approval of the use of such commercial products. All product names and trademarks cited are the property of their respective owners. The findings of this report are not to be construed as an official Department of the Army position unless so designated by other authorized documents. DESTROY THIS REPORT WHEN NO LONGER NEEDED. DO NOT RETURN IT TO THE ORIGINATOR. ERDC/GRL TR-20-3 iii
Disturbance observer‐based distributed sliding mode control of multimotor web‐winding systems

This study investigates a novel disturbance observer-based distributed sliding mode control (DOB-DSMC) strategy for the multimotor web-winding system in the presence of model uncertainties and external disturbances. First, a disturbance observer is developed for each subsystem to generate the disturbance estimations, which can be incorporated in the controller to counteract the disturbances. After that, by choosing appropriate coordination variables, a DOB-DSMC is designed, which ensures that the system states converge to the sliding surface in finite time. The proposed controller can not only reduce the effect of coupling between continuous subsystems on states but also restrain the influence of uncertainties and external disturbances. It only requires a smaller control input than linear control. The controller gain matrices are obtained by solving linear matrix inequalities, which are obtained by the H ∞ control theory and Lyapunov stability theory. Finally, some simulations and experimental tests are performed on the three-motor web-winding system to test the performance of the proposed DOBDSMC method.
Exposition au DES et projet d'enfant en 2004 : quelles problématiques, quelle prise en charge quand la grossesse ne s'initie pas spontanément ?

La Lettre du Gynécologue n° 302 mai 2005 histoire du diéthylstilbestrol (DES) n’appartient pas encore au passé : ses prescriptions ont duré en France, de 1950 à 1977 avec un pic de 1964 à 1974. Si le risque d’adénocarcinome à cellules claires (ACC) du col et du vagin s’amenuise, les complications de la reproduction de la génération exposée sont à prévoir jusqu’en 2020 environ. Un résumé de l’histoire de cette thérapeutique introduit la compréhension des problématiques de cette génération, des modalités de leur prise en charge.
Breast cancer metastasis from Gastric Carcinoma in a young female

Gastric cancer is a disease of elderly patients and mainly metastasis to liver, lung, and peritoneum, while signet ring cell is a variant of gastric cancer and commonly metastasis to peritoneum and lymph nodes. Metastasis to mammary is a rare condition which account for 3% and has poor prognosis. Generally extra mammary carcinoma precedes breast metastasis by 2 years. It’s uncommon to have breast metastasis as a first manifestation of extra mammary malignancies. There is no age limit and presentation my mimic primary breast cancer. Due to rarity of this condition there are no consensuses about clinical, radiological and histological features which make it a challenging task to distinguish primary from metastatic breast neoplasm. The case bellow is a young woman with diagnoses of diffuse-signet ring cell gastric cancer. First presentation was right breast edema with ascites, peritoneal nodules, and enlarged enhancing ovaries on imaging. Biopsy from each site confirmed involvement by metastatic adenocarcinoma with signet ring pattern. Her condition progressed after 5th cycle of EOX.
SISTEM PENDETEKSI KALIMAT UMPATAN DI MEDIA SOSIAL DENGAN MODEL NEURAL NETWORK

Governments and social media providers put high effort to tackle massive negative contents in social media. Those contents are mostly containing religion, race, and inter-group issues, cyberbullying, and also body shamming, which usually appears together with offensive languages. It becomes difficult to overcome because of a large number of internet users in Indonesia. Hence, we need a system that can automatically detect the negative contents. This paper utilizes Neural Network (NN) models for not only classifying the words as (non)offensive words but also considering the structure of the sentence to get its context. There are two NN models analyzed in this paper: Artificial Neural Network (ANN) and Recurrent Neural Network (RNN). The computer simulation results show that the RNN has better performances than the ANN with the accuracy of training, validation, and testing 94%, 84%, and 84%, respectively. Pemerintah dan penyedia layanan media sosial di Indonesia berusaha keras untuk mengatasi maraknya konten negatif di media sosial. Konten negatif yang sering ditemui diantaranya isu suku, agama, ras, dan antargolongan (SARA), cyberbullying, serta body shamming, yang biasanya muncul disertai kalimat-kalimat umpatan. Hal tersebut menjadi sulit untuk diatasi karena jumlah pengguna internet di Indonesia yang sangat besar, sehingga perlu adanya sebuah sistem yang dapat mendeteksinya secara otomatis. Penelitian ini mengusulkan sistem dengan model Neural Network untuk deteksi konten negatif di media sosial dengan cara mempertimbangkan konteks kalimat atau frasa, tidak hanya kata-per-kata. Ada dua model NN yang dianalisis di penelitian ini, yaitu Artificial Neural Network (ANN) dan Recurrent Neural Network (RNN). Model RNN menunjukkan performa yang lebih baik dibandingkan dengan model ANN dengan akurasi training, validasi, dan test masing-masing adalah 94%, 84%, dan 84%.
Propostas de um modelo para o tráfego de redes de comunicações e de funções de janela para o filtro FIR utilizado na tecnologia f-OFDM

Neste trabalho, a fim de modelar os processos de trafego de redes de comunicacoes, propoe- se um modelo multifractal eficiente que utiliza menos parâmetros que outros modelos presentes na literatura. O modelo MEV (Modelagem Exponencial para a Variância dos multiplicadores) e baseado em uma cascata multiplicativa no dominio wavelet capaz de sintetizar amostras de trafego de redes de comunicacoes que apresentam caracteristicas como autossimilaridade e ampla Largura de Espectro Multifractal (MSW). Para tal finalidade, no modelo MEV, captura-se o decaimento de energia dos coeficientes wavelet por meio de parametrica baseada em uma distribuicao exponencial para a variância dos multiplicadores ao longo dos estagios da cascata. Avalia-se o desempenho do modelo MEV em descrever as caracteristicas do trafego de redes em comparacao a outros modelos presentes na literatura. Para tanto, sao utilizadas series reais de trafego de redes de comunicacoes. Alem disso, propoe-se uma classe de funcoes de janela ajustaveis baseadas na distribuicao de Nakagami para a construcao do filtro digital sinc-janelado utilizado pela tecnologia f-OFDM. Comparam- se os desempenhos dos filtros sinc-janelados em termos de eficiencia espectral e emissao fora de banda (OOBE) analisando resultados de densidade espectral de potencia (PSD). Alem disso, verifica-se o tempo de processamento do filtro de resposta ao impulso finito (FIR) utilizando diferentes funcoes de janela e a taxa de erro de bit (BER) no processo de transmissao de dados. Comparam-se os resultados obtidos utilizando a f-OFDM com aqueles obtidos por meio da tecnologia OFDM sem filtragem e tambem com as tecnologias FBMC e UFMC. Os resultados obtidos mostram que a tecnologia f-OFDM (especialmente utilizando as janelas de Nakagami) e uma candidata a ser utilizada nas proximas geracoes de sistemas de comunicacoes moveis, visto que comparada a tecnologia OFDM, mantem as suas vantagens, por exemplo a robustez a ISI, ao mesmo tempo que diminui uma de suas desvantagens, a emissao fora de banda (OOBE).
A Rare Case of Bilateral Temporal Arteritis in a 40-year-old Patient

Introduction: Temporal arteritis (TA) is a chronic inflammatory vasculitis involving medium and large arteries, which mostly oc- curs after the age of 50 and involves one side of the body. Case Presentation: We present a 40-year-old male patient with simultaneous bilateral temporal arteritis along with a headache, mild fever, palpation of temporal arteries and anemia who responded to 1 mg/kg oral daily prednisone for three months. This patient was referred to the Pars Hospital in Tehran, Iran on March 2016. Conclusions: Temporal arteritis should be kept in mind as an important curable dierential diagnosis, not only in ages above 50,
Muhasebe Hizmeti Alan Mükelleflerin Kişilik Özelliklerinin Müşteri Bağlılığı İle İlişkisi

Many recent studies have tried to understand people. In essence, these studies try to analyze human attitudes and behaviors. When considering the organizational basis, the attitudes and behaviors of the employees play an important role in achieving the organizational goals and objectives. Enneagram personality traits are used to understand human attitudes and behaviors. Businesses will be able to capture success when they see both their employees and consumers as the ring of a chain. The aim of this study is to determine the relationship between Enneagram and Customer Loyalty. For this purpose, the 201 taxpayer who received accounting services from certified public accountant and financial advisor in Kutahya province was reached on a voluntary basis. Enneagram has recently become one of the concepts we often hear on both social media and academia. Customer loyalty remains a concept that marketers often emphasize. Our findings revealed very weak-weak and moderate relationships between Enneagram personality traits and customer loyalty. In addition, Enneagram personality traits have been found to affect both Customer Loyalty and its sub-factors. The highest correlation with customer loyalty was found to be with “Type-7 adventurer” while the lowest correlation was with “Type-2 helper”.
Two-Body Spinless-Salpeter equation of unequal masses interacting with Coulomb-Hulthẻ n potential

We obtained the analytical solutions of the two-body Salpeter equation via the methodology of supersymmetric quantum mechanics under a combination of Coulomb and Hulthén potentials for unequal masses. We clearly examined the energy eigenvalues for the ground state and excited states. The behaviour of energy with the sum of the masses and the screening parameter respectively, were also studied. The results showed that two bodies of unequal masses interacting within the system exhibit the same features.
A DUAL-MODE RESONATOR-FED GAP COUPLED FILTERING ANTENNA WITH IMPROVED SELECTIVITY AND BANDWIDTH

A novel dual-mode resonator-fed filtering patch antenna with improved selectivity and bandwidth is proposed in this paper. Unlike well-known cascaded-resonator structure, the proposed filtering antenna shows five poles in the reflection coefficient response utilizing only one resonator. The gap-coupled radiating part introduces two gain zeros along each side of the gain response. Meanwhile, the dual-mode resonator feeding structure of the antenna will also produce another two gain zeros. All these four gain zeros highly improve the selectivity of the filtering antenna without increasing the number of coupling resonators. In addition, the bandwidth of the antenna is also considerably extended using this feeding structure. For validation, a prototype is designed, fabricated, and measured. The measured results agree well with the simulated ones.
Les tumeurs germinales malignes de l'ovaire chez la petite fille

L es tumeurs germinales malignes (TGM) se définissent comme des tumeurs dérivant de la transformation maligne des cellules germinales, cellules totipotentes. Elles peuvent se localiser n’importe où entre la tête et le coccyx. Mais chez la fille, la localisation ovarienne est la plus fréquente. Ces tumeurs, très rares, sont caractérisées par leur polymorphisme histologique et parfois par la présence de marqueurs tumoraux, notamment l’αFP et la βHCG. Le pronostic de ces tumeurs a été amélioré par l’utilisation de la chimiothérapie.
Cefuroxime-induced thrombocytopenia: it’s just not in the ring??

Beta lactams are one of the most commonly used antibiotic groups in clinical practice, owing to their relatively superior safety profile, when weighed against other available antibiotics. Cephalosporins have overgrown over the years, now extending across five generations of drugs. Older cephalosporins are still commonly used, chiefly because of their low cost and minimal adverse effects. However, no drug is entirely free of adverse effects. Cephalosporins (especially those with a methylthiotetrazole ring) have been associated with bleeding manifestations due to hypoprothrombinemia and thrombocytopenia in susceptible subsets of the global population. This case report concerns the use of a cephalosporin that does not have this ring in its structure, but has still caused a rare instance of thrombocytopenia Keywords: Beta lactam, Cefuroxime, Platelets, Bleeding, Methylthiotetrazole.
Teacher politics bottom-up: theorising the impact of micro-politics on policy generation

ABSTRACT Education policy is generally understood as a multi-layered process, consisting of diverse interconnected phases. Studies of these interconnections typically ask whether and how the generation of official policy from the top-down affects micro-politics, i.e. how teachers experience and execute their work. The assumption that policy is influenced in the reverse direction is widely held, but has seldom been studied empirically. Little is known, therefore, about how this dynamic operates. This study delineates mechanisms that link teachers’ micro-politics to the macro-politics of policy generation. Analytically, it combines concepts from the literature on teacher involvement in macro- and micro-politics in order to develop a framework bridging the two. Empirically, it harnesses the theoretical potential of Swiss language education policy, tracing the process of reforms through which teachers, though formally excluded from policy-making, were able to influence the choice of languages included in official curricula. The analysis identifies three mechanisms through which they exerted influence: voicing experience, subversive enactment, and open resistance. None of these are dependent upon higher levels of teacher unionisation or particular institutions of governance. These findings highlight the importance of engaging with the processual dimension of politics to advance our theories of educational policy.
Perspectives on the Nutritional Management of Metabolic Syndrome in Asia: People, Practice and Programmes

Abstract Numerous Asian countries have a high prevalence of metabolic syndrome, also associated with cardiovascular disease and diabetes mellitus. Healthcare expenditure varies among Asian countries, and is influenced by poverty factor and large populations. The effect of metabolic syndrome on nutritional management in Asia demonstrates the essential for clinicians to equalize the needs for higher standards of dietetics practice; as they execute optimal care processes with the aim of improving outcomes, alongside setting of workforce limitations, inadequate expertise in metabolic syndrome nutrition practice, as well as ethnic diversity among Asians. This paper presents some aspects of dietetics practice and the possibility that an alteration in practice is mandatory if dietitians are to play an active role in preventing or decelerating the evolution of the metabolic syndrome.
SGN-35, an Anti-CD30 Antibody-Drug Conjugate, Exhibits Potent Antitumor Activity for the Treatment of CD30+ Malignancies.

Hodgkin/Reed-Sternberg (H-RS) and anaplastic large cell lymphoma (ALCL) cells express high levels of the cell surface receptor CD30, a member of the TNF receptor superfamily. To augment the antitumor activity of anti-CD30 based therapies, a novel synthetic anti-mitotic agent, monomethyl auristatin E (MMAE), has been conjugated to the anti-CD30 antibody cAC10. MMAE was synthetically modified to include a maleimide for conjugation to an antibody and a protease cleavable Val-Cit peptide linker to release the drug from the antibody. The in vitro and in vivo activity of SGN-35, the resulting antibody-drug conjugate, is outlined. SGN-35 has an average of four MMAE molecules per antibody. Cell surface binding, internalization and intracellular release of MMAE were monitored by immunofluoresence and isotope labeling methods. The H-RS cell line L540cy translocates SGN-35 to lysosomes within 16 hours. Analysis of the cellular contents demonstrated that MMAE is rapidly and efficiently liberated from the antibody, and MMAE accumulates inside the cells. After treating L540cy cells with 200 ng/mL of SGN-35 (6 nM MMAE), the intracellular concentration of MMAE reaches 800 nM after 24 hours, rising to nearly 1000 nM after 72 hours. From 24 to 72 hours, about 70% of the intracellular drug is liberated MMAE, while 30% is still bound to the antibody. In vitro potency of SGN-35 was measured by incubating various concentrations of SGN-35 with CD30+ tumor cells and measuring cell viability in culture. SGN-35 had potent, selective in vitro activity with IC50s ranging from 4 to 35 ng/mL for CD30+ cell lines, and an IC50 > 1000 ng/mL for the CD30− line WSU-NHL. This demonstrates that the conjugation of the novel cytotoxic agent MMAE to an antibody can be accomplished without compromising the antibody’s specific binding and internalization. SCID mice were implanted with L540cy and treated with intravenous doses of SGN-35. In mice bearing L540cy xenografts, complete tumor regressions were achieved at doses as low as 2 mg/kg q4dx4. SGN-35 is also highly effective in treating mice with disseminated L540cy implants, at well tolerated doses. Based on the potent cytotoxicity, efficacy in xenograft models, and tolerability, SGN-35 is being advanced toward clinical development in CD30-positive hematologic malignancies.
Bilateral series resonant inverter for high frequency link UPS

A description is given of a bilateral series-resonant inverter for high-frequency link uninterruptible power supply. The inverter consists of a zero-current-switched series-resonant power converter, a high-frequency transformer, and a zero-current-switched cycloconverter, whereby bidirectional power flow is possible and high efficiency is obtained. The output voltage is regulated by controlling the resonant tank energy, and the switching pattern of the cycloconverter is fixed to obtain the high-frequency transformer. A novel control scheme to minimize the output ripple voltage is suggested and verified through computer simulation, and the effects of the circuit parameters on the output voltage ripple are discussed. <<ETX>>
Perinatal psychiatry: a new specialty or everyone’s business?

Perinatal psychiatry is a relatively new subspecialty and controversy exists about such specialist provision. Differences can occur in how mental illnesses present in pregnancy, and there is a need to take into account both mother and baby. The risks of not treating perinatal mental illness can be both acute and chronic, and suicide in the context of untreated illness remains a leading indirect cause of maternal mortality. Despite the government's agenda of preventive healthcare, service provision is inequitable across the UK. Advice regarding treatment continues to be complex, and perinatal psychiatrists need to keep abreast of a growing evidence base. This review offers an overview of some current issues in the care of patients in the perinatal period and shows how specialised perinatal services are uniquely placed to meet their needs. Hopefully, it will prove useful to all clinicians responsible for the perinatal care of women and their families.