Miracle-dz/UniFAR-FTUs huggingface dataset:
Attacks on RFID Protocols

This document consists of a description of attack methodologies and a collection of detailed attacks upon RFID protocols. It is meant to serve as a quick and easy reference and it will be updated as new attacks are found. Currently the only attacks on protocols shown in full detail are the authors’ original attacks with references to similar attacks on other protocols. The main security properties considered are authentication, untraceability, and desynchronization resistance.
Robust Fault Diagnosis by Using Bond Graph Approach

This paper deals with the generation of fault indicators and residual thresholds in the presence of parameter uncertainties by using a bond graph representation in linear fractional transformation (LFT) form. The residuals' sensitivity analysis, which is based on the fault detectability indexes, is used for residuals evaluation. The developed algorithms are applied on an electromechanical test bench system for on-line fault detection and isolation. Simulation and experimental tests show the influence of dead zone magnitude and variations of system parameters on the residuals.
Correlation between apoptosis, proliferation and bcl-2 expression in malignant non-Hodgkin's lymphoma

Aim—To investigate whether clinical features of non-Hodgkin's lymphomas, at the time of first biopsy, correlate with studies of cell proliferation and cell death as well as with the level of bcl-2 expression. Methods—Bcl-2 expression, determined by immunocytochemistry, was compared with cell proliferation, measured using in situ hybridisation for histone mRNA, and cell death by apoptosis, measured using in situ end labelling for DNA cleavage. Results—Histone mRNA staining gave a labelling index of 30% of cells for reactive germinal centres, 5.2-13.5% of cells for low grade non-Hodgkin's lymphoma and 12.1-50.5% of cells for high grade non-Hodgkin's lymphoma. In situ end labelling gave a labelling index of 5.0-10.0% of cells for reactive germinal centres, 1.0-3.7% of cells for low grade non-Hodgkin's lymphoma and 4.7-13.5% of cells for high grade non-Hodgkin's lymphoma. There was a positive correlation between apoptotic index and proliferation index. More cases of low grade than high grade non-Hodgkin's lymphoma expressed bcl-2. There was no correlation between apoptotic index and bcl-2 expression for high grade non-Hodgkin's lymphoma. Conclusions—The molecular mechanisms controlling cell proliferation and death in non-Hodgkin's lymphoma are complex, probably involving a range of genes, including bcl-2. A better understanding of resistance to cell death is needed if the clinical goal of tailoring cancer treatment to individual tumours is to be achieved.
Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting: implications for measurement of circulating VEGF levels in clinical disease.

1. Dysregulated vascular endothelial growth factor (VEGF) expression has been reported in several pathological states based upon evidence of elevated serum VEGF levels. Using two immunoassays for VEGF, this study determines normal plasma and serum VEGF ranges, determines which are more likely to reflect circulating VEGF levels and investigates a potential contribution of VEGF from platelets to VEGF levels detected in serum. 2. The presence of soluble VEGF receptor, sflt-1, at a molar excess of 7:1 significantly reduced measured VEGF levels in both assays. Serum VEGF levels were higher than plasma levels in children [(mean +/- S.E.M.) 306.1 +/- 39.4 versus 107.4 +/- 24.9 pg/ml, P < 0.0001] and adults (249.4 +/- 46.4 versus 76.1 +/- 10.7 pg/ml, P < 0.0001). Serum VEGF increased with clotting time (P = 0.0005 t0 compared with 2 h samples); plasma VEGF levels were not affected by time between sampling and centrifugation. 3. Calcium-induced clotting of platelet-rich but not platelet-poor plasma induced VEGF release with a proportional response between platelet count and VEGF level and isolated platelets released significant quantities of VEGF upon incubation with thrombin. Reverse transcriptase-PCR studies confirmed that platelets express VEGF121 and VEGF165 mRNA. 4. These data suggest that plasma is the preferred medium to measure VEGF levels; a significant and highly variable platelet-mediated secretion of VEGF during the clotting process invalidates the use of serum as an indicator of circulating VEGF levels in disease states.
Settlement archaeology: World‐wide comparisons

Abstract Site sizes have been reported by archaeologists all over the world in the past 150 years. Now that numerous site size reports are becoming available from contract work and surveys for cultural resource management as well as from regional research programmes we need seriously to consider whether there really is sufficient intercomparability for this mass of data to be generally useful. Despite assumptions about inter‐regional inconsistencies in data collection there appears to be a world‐wide consistency in the way site size has been identified. Consistent patterns of site size distribution and rates of change are recognisable. Site size appears to be adequate as a gross referent of settlement size. A behavioural model of the interaction and communication constraints on community life provides an explanation of the large scale processes of settlement growth.
Cellular and molecular mechanisms of asbestosis.

O and experimental exposure to asbestos is associated with the development of peribronchiolar and interstitial pulmonary fibrosis.1 L ike other asbestosassociated diseases of the respiratory tract (ie, mesothel ioma and bronchogenic carcinoma), asbestosis appears to involve alterations in differentiation and proliferation o f affected cel l types. W h e t h e r the disease process involves e i ther an increase in replication o f fibroblasts in the lung or an enhanced ability o f individual fibroblasts to produce more collagen or both is uncertain. To address this question, we used a combination o f in vitro and in vivo approaches.
Capturing the Voices of Pseudepigraphic Personae: On the Form and Function of Incipits in the Aramaic Dead Sea Scrolls

Abstract It is widely recognized that the authors of the Aramaic Dead Sea Scrolls often shrouded their tales in first person voices and exhibited a perennial interest in the production and transmission of ancestral booklore. The present study explores the literary convention of the incipit in light of these interrelated methods of pseudepigraphy. Throughout the Aramaic Scrolls incipits introduce entire compositions and putative texts within narratives. Comparative philological analysis reveals that these incipits feature strikingly similar literary-linguistic idioms. However, it is equally apparent that that these common elements were uniquely patterned by individual authors. It is suggested that these commonalities should inform how we conceive of the scribal milieu(s) from which the Aramaic Scrolls emerged and our understanding of pseudepigraphy in early Judaism. The article concludes with a fresh proposal for the function of the title “A Copy of the Writing of the Words of Noah” in 1QapGen 5:29.
Molecular Characterization of hsp20, Encoding a Small Heat Shock Protein of Bifidobacterium breve UCC2003

ABSTRACT Small heat shock proteins (sHSPs) are members of a diverse family of stress proteins that are important in cells to protect proteins under stressful conditions. Genome analysis of Bifidobacterium breve UCC2003 revealed a single sHSP-encoding gene, which was classified as a hsp20 gene by comparative analyses. Genomic surveillance of available genome sequences indicated that hsp20 homologs are not widely distributed in bacteria. In members of the genus Bifidobacterium, this gene appears to be present in only 7 of the 30 currently described species. Moreover, phylogenetic analysis using all available bacterial and eukaryotic sHSP sequences revealed a close relationship between bifidobacterial HSP20 and the class B sHSPs found in members of the division Firmicutes. The results of this comparative analysis and variation in codon usage content suggest that hsp20 was acquired by certain bifidobacteria through horizontal gene transfer. Analysis by slot blot, Northern blot, and primer extension experiments showed that transcription of hsp20 is strongly induced in response to severe heat shock regimens and by osmotic shock.
Cloud Task Scheduling Based on Swarm Intelligence and Machine Learning

Cloud computing is the expansion of parallel computing, distributed computing. The technology of cloud computing becomes more and more widely used, and one of the fundamental issues in this cloud environment is related to task scheduling. However, scheduling in Cloud environments represents a difficult issue since it is basically NP-complete. Thus, many variants based on approximation techniques, especially those inspired by Swarm Intelligence (SI) have been proposed. This paper proposes a machine learning algorithm to guide the cloud choose the scheduling technique by using multi criteria decision to optimize the performance. The main contribution of our work is to minimize the makespan of a given task set. The new strategy is simulated using the CloudSim toolkit package where the impact of the algorithm is checked with different numbers of VMs varying from 2 to 50, and different task sizes between 30 bytes and 2700 bytes. Experiment results show that the proposed algorithm minimizes the execution time and the makespan between 7% and 75%, and improves the performance of the load balancing scheduling.
Marking axillary lymph nodes with radioactive iodine seeds for axillary staging after neoadjuvant systemic treatment in breast cancer patients: the MARI procedure.

OBJECTIVE The MARI procedure [marking the axillary lymph node with radioactive iodine (I) seeds] is a new minimal invasive method to assess the pathological response of nodal metastases after neoadjuvant systemic treatment (NST) in patients with breast cancer. This method allows axilla-conserving surgery in patients responding well to NST. METHODS Prior to NST, proven tumor-positive axillary lymph nodes were marked with a I seed. This marked lymph node is the so-called MARI-node. After NST, the MARI node was selectively removed using a γ-detection probe. A complementary axillary lymph node dissection was performed in all patients to assess whether pathological response in the MARI node was indicative for the pathological response in the additional lymph nodes. RESULTS A tumor-positive axillary lymph node was marked with a I seed in 100 patients. The MARI node was successfully identified in 97 of these 100 patients (identification rate 97%). Two patients did not undergo subsequent axillary lymph node dissection, leaving 95 patients for further analysis. The MARI node contained residual tumor cells in 65 of these 95 patients. In the other 30 patients, the MARI node was free of tumor, but additional positive lymph nodes were found in 5 patients. Thus, the MARI procedure correctly identified 65 of 70 patients with residual axillary tumor activity (false negative rate 5/70 = 7%). CONCLUSIONS This study shows that marking and selectively removing metastatic lymph nodes after neoadjuvant systemic treatment has a high identification rate and a low false negative rate. The tumor response in the marked lymph node may be used to tailor further axillary treatment after NST.
Functional pathway analysis of genes associated with response to treatment for chronic hepatitis C

Summary. Chronic hepatitis C (CH‐C) is among the most common causes of chronic liver disease. Approximately 50% of patients with CH‐C treated with pegylated interferon‐α and ribavirin (PEG‐IFN‐α + RBV) achieve a sustained virological response (SVR). Several factors such as genotype 1, African American (AA) race, obesity and the absence of an early virological response (EVR) are associated with low SVR. This study elucidates molecular pathways deregulated in patients with CH‐C with negative predictors of response to antiviral therapy. Sixty‐eight patients with CH‐C who underwent a full course of treatment with PEG‐IFN‐α + RBV were included in the study. Pretreatment blood samples were collected in PAXgene™ RNA tubes. EVR, complete EVR (cEVR), and SVR rates were 76%, 57% and 41%, respectively. Total RNA was extracted from pretreatment peripheral blood mononuclear cells, quantified and used for one‐step RT‐PCR to profile 154 mRNAs. The expression of mRNAs was normalized with six ‘housekeeping’ genes. Differentially expressed genes were separated into up and downregulated gene lists according to the presence or absence of a risk factor and subjected to KEGG Pathway Painter which allows high‐throughput visualization of the pathway‐specific changes in expression profiles. The genes were consolidated into the networks associated with known predictors of response. Before treatment, various genes associated with core components of the JAK/STAT pathway were activated in the cohorts least likely to achieve SVR. Genes related to focal adhesion and TGF‐β pathways were activated in some patients with negative predictors of response. Pathway‐centred analysis of gene expression profiles from treated patients with CH‐C points to the Janus kinase‐signal transducers and activators of transcription signalling cascade as the major pathogenetic component responsible for not achieving SVR. In addition, focal adhesion and TGF‐β pathways are associated with some predictors of response.
Cervical cancer screening by enhanced cytology: application of novel markers.

Cervical cytological examination is the most widely applied screening method for cervical cancer and its precursors. Liquid-based cytology produces goodquality smears1 and enables the use of ancillary laboratory techniques to distinguish neoplastic from benign cells.1 Immunohistochemical and molecular markers have been tested to identify dysplastic cells in cervical smears. When testing for human papillomavirus (HPV) or chromosome aneusomy, MIB1 (Ki67) and p16 immunocytochemistry helps to highlight dysplastic or cancer cells.2 Such markers may be useful for triage of patients with borderline smears of atypical squamous cells of undetermined significance (ASCUS), which is the most common abnormal cytological finding and is associated with a significantly higher risk of developing cervical cancer and its high-grade precursors. In this study, immunocytochemical markers (p63, p73, Eif-5A2, and DJ-1 genes) were tested in cervical cancer screening using immunocytochemistry and chromogenic in situ hybridisation. Differential expression of these genes in cervical cytology is useful in diagnosing cervical cancer. p63 and p73 genes are members of the p53 family and play important roles in carcinogenesis. Different isoforms of p63 and p73 can enhance or suppress neoplastic cell growth. Differential expression of p63 and p73 isoforms was reported in normal and neoplastic cervical epithelium. p73 expression is associated with radiosensitivity of cervical cancer.3 In a study of frequently amplified regions at 3q26.2, Eif-5A2 was found to be important Hong Kong Med J 2014;20(Suppl 6):S39-43 RFCID project number: 06060642 ANY Cheung *, XY Guan, HYS Ngan
The Strong Situation Hypothesis

A conventional wisdom in personality and social psychology and organizational behavior is that personality matters most in weak situations and least in strong situations. The authors trace the origins of this claim and examine the evidence for the personality-dampening effect of strong situations. The authors identify the gap between claim and evidence and suggest an agenda for future research.
Conserved Helix 7 Tyrosine Acts as a Multistate Conformational Switch in the 5HT2C Receptor

Studies in many rhodopsin-like G-protein-coupled receptors are providing a general scheme of the structural processes underlying receptor activation. Microdomains in several receptors have been identified that appear to function as activation switches. However, evidence is emerging that these receptor proteins exist in multiple conformational states. To study the molecular control of this switching process, we investigated the function of a microdomain involving the conserved helix 7 tyrosine in the serotonin 5HT2C receptor. This tyrosine of the NPXXY motif was substituted for all naturally occurring amino acids. Three distinct constitutively active receptor phenotypes were found: moderate, high, and “locked-on” constitutive activity. In contrast to the activity of the other receptor mutants, the high basal signaling of the locked-on Y7.53N mutant was neither increased by agonists nor decreased by inverse agonists. The Y7.53F mutant was uncoupled. Computational modeling based on the rhodopsin crystal structure suggested that Y7.53 interacts with the conserved aromatic ring at position 7.60 in the recently identified helix 8 domain. This provided a basis for seeking revertant mutations to correct the defective function of the Y7.53F receptor. When the Y7.53F receptor was mutated at position 7.60, the wild-type phenotype was restored. These results suggest that Y7.53 and Y7.60 contribute to a common functional microdomain connecting helices 7 and 8 that influences the switching of the 5HT2C receptor among multiple active and inactive conformations.
Operations strategy frameworks in manufacturing, services and product-service systems

Many definitions for operations strategy appear in literature. Yet, after analysing some of these important definitions, there were some common denominators: planning and decision-making. It is through correct operations strategy planning and decisions that organizations achieve competitive edge, and for this reason, the subject is of major importance. In this paper we present a review on operations strategy (OS) in manufacturing, services and product-service organizations. Through the literature analysis we found several differences and fewer similarities between OS in manufacturing and services and also the positioning of product-service systems (PSS) OS, comparing to OS in manufacturing and in services. Our foremost contribution is providing a literature review and an analysis on the content of the OS frameworks.
OBSIDIAN BIFACE PRODUCTION AT TEOTIHUACAN: REEXAMINING A COYOTLATELCO PHASE WORKSHOP FROM HACIENDA METEPEC

Abstract This paper provides a reanalysis of a specialized biface workshop at Coyotlatelco-phase (a.d. 650–800) Teotihuacan excavated by Evelyn Rattray in 1979. Although Teotihuacan had already declined as a major center prior to this phase, the resident population was still being serviced by a variety of craftsmen, including knappers. The remains of an obsidian workshop at Hacienda Metepec give insight into workshop production within Epiclassic-period Teotihuacan. A single workshop produced between 4,700 and 8,700 projectile points similar in shape to San Marcos points. The homogeneous workmanship indicates a single knapper, perhaps over several years of effort.
Caractérisation physico-chimique de la gomme Sterculia de trois localités de la région de Tambacounda au Sénégal

La gomme sterculia est produite par Sterculia setigera Del. en Afrique. Ses proprietes physicochimiques changent suivant divers facteurs dont l’influence sur sa qualite a ete peu etudiee. C’est dans cette perspective que l’humidite, le pH, le pouvoir gonflant et la viscosite de cette gomme ont ete evalues au Senegal (Daoudi, Malem niani et Bala). Les resultats ont montre que son humidite varie en fonction du phenotype (ecorce claire ou foncee). Elle a ete plus elevee sur la gomme de la periode seche-chaude a Daoudi mais elle n’a pas change suivant le site apres un an de conservation. Son pH a varie en fonction de l’interaction periode de saignee- couleur de l’ecorce a Malem Niani alors qu’a Daoudi il a varie suivant la periode de saignee seulement. A Malem, son gonflement a aussi varie suivant l’interaction periode de saignee-couleur de l’ecorce. Apres un an de conservation (temperature ambiante), son pouvoir gonflant a diminue dans tous les sites. Sa viscosite a ete 3,5 fois plus elevee a Bala qu’a Daoudi et Malem Niani. Ces resultats ont permis d’acquerir de nouvelles connaissances et d’identifier Bala comme ayant la meilleure qualite de gomme par rapport aux deux autres sites. Mots cles : Acidite, Humidite, pouvoir de gonflement, Sterculia setigera Del. , Tambacounda, viscosite
How Much Do Formula-Fed Infants Take in the First 2 Days?

Objective. To document the intake of exclusively formula-fed newborns during the first 2 days of life. Methods. We enrolled a cohort of 50 healthy newborns ≥37 weeks’ gestation and documented their daily formula intake until discharge. We surveyed pediatricians regarding their assessment of the intake of formula fed infants. Results. In all, 37 of 50 newborns stayed for at least 48 hours. The mean ± SD gestational age was 39.5 ± 0.88 weeks. Mean ±SD formula intake for the first 48 hours (n = 37) was 57.2 ± 20.4 mL/kg/d and mean weight loss at 45.7 ± 8.8 hours, was 2.7% of birth weight. Pediatricians underestimated the amounts taken by these infants. Conclusions. In the first 2 days, healthy term newborns, fed formula ad lib, consume about 115 mL/kg, about 2 to 3 times as much as breastfed infants, and they lose only 2.7% of their birthweight by 48 hours. Most pediatricians underestimate the intake of formula-fed infants.
An inducible helix–Gly–Gly–helix motif in the N‐terminal domain of histone H1e: A CD and NMR study

Knowledge of the structural properties of linker histones is important to the understanding of their role in higher‐order chromatin structure and gene regulation. Here we study the conformational properties of the peptide Ac‐EKTPVKKKARKAAGGAKRKTSG‐NH2 (NE‐1) by circular dichroism and 1H‐NMR. This peptide corresponds to the positively charged region of the N‐terminal domain, adjacent to the globular domain, of mouse histone H1e (residues 15–36). This is the most abundant H1 subtype in many kinds of mammalian somatic cells. NE‐1 is mainly unstructured in aqueous solution, but in the presence of the secondary‐structure stabilizer trifluoroethanol (TFE) it acquires an α‐helical structure. In 90% TFE solution the α‐helical population is ∼40%. In these conditions, NE‐1 is structured in two α‐helices that comprise almost all the peptide, namely, from Thr17 to Ala27 and from Gly29 to Thr34. Both helical regions are highly amphipathic, with the basic residues on one face of the helix and the apolar ones on the other. The two helical elements are separated by a Gly–Gly motif. Gly–Gly motifs at equivalent positions are found in many vertebrate H1 subtypes. Structure calculations show that the Gly–Gly motif behaves as a flexible linker between the helical regions. The wide range of relative orientations of the helical axes allowed by the Gly–Gly motif may facilitate the tracking of the phosphate backbone by the helical elements or the simultaneous binding of two nonconsecutive DNA segments in chromatin.
Acinar cell apoptosis and the origin of tubular complexes in caerulein‐induced pancreatitis

The interrelationship between acinar cell apoptosis and tubular complex formation was examined in caerulein‐induced pancreatitis using histology, immunohistochemistry, electron microscopy and DNA gel electrophoresis. Rats were given 8 hourly subcutaneous injections of caerulein, 24μg/kg, for up to 2 days. Morphologically and biochemically typical apoptosis affected 4.6 and 8.9% of acinar cells at 1 and 2 days, respectively, resulting in removal of most acinar cells by 2 days. Consequently, pancreatic ducts, the lining cells expressing bcl‐2 and therefore resistant to apoptosis, became much more closely approximated to form the basis of tubular complexes; small numbers of immunohistochemically discrete acinar cells in their lining were either pre‐apoptotic resistant to it or newly formed. Proliferation of duct‐like lining cells was associated with apoptosis, an increase in islet cells and acinar cell regeneration. There was evidence of duct to acinar cell differentiation but the main increase in acinar cell numbers appeared to derive from proliferation of newly formed acinar cells.