Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Functional Training on Performance in Professional Basketball Players

Objectives: The purpose of this study was to determine whether functional training had any effects on performance and related various physical components of basketball players. Materials and Methods: 28 athletes participated from first and second division professional basketball teams of one club. While first division basketball team players (n=14, average age: 26.6 ± 5.9 years) were assigned into functional training group (FTG), second division basketball team players (n=14, average age: 22.4 ± 4.2 years) were assigned into control group (CG). FTG completed a functional training program which included core strengthening and specific basketball task-related exercises with/without equipment. CG followed traditional strength training consisted of machine and free weight lifting based exercises. Both groups performed trainings for 20 weeks (2 days/week with 75-85 min. duration) along with the routine basketball practice. Anthropometric measurements, sit and reach flexibility test, 20 m speed test, T-drill and Lane-agility tests, horizontal and vertical jump tests, one-repetition maximum bench press and leg press strength tests were assessed before and after the 20-week program. Results: The results of this study was indicated that the FTG significantly improved upper and lower body strength, flexibility, vertical jump ability and T-drill agility scores relative to the CG (p<0.05). Conclusions: These findings demonstrate that the functional training (FT) can be an alternative method to traditional resistance training for improving performance-related parameters such as flexibility, vertical jump ability, agility, and strength. Further researches are needed to study with the different parameters about athletic performance in other sport disciplines and with larger sample size.
Temporal variation in dispersal modifies dispersal-diversity relationships in an experimental seagrass metacommunity

: Dispersal is a key force driving patterns of biodiversity. However, temporal variation in dispersal due to seasonality, weather, and other stochastic forces is an understudied aspect of the dispersal–diversity relationship. Metacommunity theory predicts temporal variation in dispersal can alter species distributions across patches. We empirically tested the hypothesis that variation in dispersal can modify the nonlinear dispersal–diversity relationship. Using a mesocosm experiment, we factorially manipulated variation in and intensity of dispersal in invertebrate grazer communities associated with nearshore seagrass ecosystems. Higher dispersal intensity led to higher grazer abundance, higher species richness (alpha diversity), and — when dispersal was variable — lower compositional similarity among patches (higher beta diversity). Within each dispersal intensity treatment level, temporal variation in dispersal decreased alpha diversity and increased beta diversity, with strongest effects at low- and intermediate-intensity dispersal. Our results provide the first empirical evidence that temporal variation in dispersal can substantially modify the well-described dispersal–diversity relationship for both alpha and beta diversity. Broadly, our results provide increasing evidence for the effects of spatial and temporal variability in modifying the role of the ecological processes driving marine metacommunity structure.
Optimal versioning strategies for software firms in the competitive environment

Software-as-a-service (SaaS) is gaining tremendous popularity in the enterprise software releases, which has brought the growing challenge for the incumbent used to adopt the on-premise licensing model. In this paper, we focus on the optimal versioning strategy problem of the incumbent when he faces the competition from the entrant who releases the SaaS software. He can choose from providing the upgraded on-premise software, turning to offer the SaaS version of the software, and releasing both the versions. We indicate that releasing both versions won't be the optimal choice in the competitive environment. When the upgrade cost is above a certain value, and the gap of value is below a threshold positively linear correlated with the upgrade cost, the incumbent prefers the SaaS strategy. Otherwise, the on-premise strategy generates the highest profit. A special case is that in the medium switching cost environment, the SaaS strategy can be optimal for all possible values of upgrade cost. Finally, We consider the problem in the presence of network effect and in the uncovered market setting. The results provide effective managerial insights into the strategy selection for the incumbent.
Perinatal Programming of Mucosal Stromal Cell Identity by the Lymphotoxin Pathway Regulates Mucosal Immune Responses in the Adult

Redundant mechanisms support IgA responses to intestinal antigens. These include multiple priming sites (mesenteric lymph nodes (MLN), Peyer’s patches and isolated lymphoid follicles) and various cytokines that promote class switch to IgA, even in the absence of T cells. In spite of these back-up mechanisms, vaccination against enteric pathogens such as Rotavirus has limited success in some populations. Genetic and environmental signals experienced during early life are known to influence mucosal immunity, yet the mechanisms for how these exposures operate remain unclear. Here we used Rotavirus infection to follow antigen-specific IgA responses through time and in different gut compartments. Using genetic and pharmacological approaches, we tested the role of a pathway known to support IgA responses (Lymphotoxin – LT) at different developmental stages. We found that LT-beta receptor (LTβR) signalling in utero programs intestinal IgA responses in adulthood by affecting antibody class switch recombination to IgA and subsequent generation of IgA antibody-secreting cells within an intact MLN. In addition, in utero LTβR signalling dictates the phenotype and function of MLN stromal cells in order to support IgA responses in the adult. Collectively, our studies uncover new mechanistic insights into how in utero LTβR signalling impacts mucosal immune responses during adulthood. One Sentence Summary Early life LTβR signalling is critical for programming the mesenteric lymph node stromal cell environment, impacting both antibody isotype switching to IgA and the differentiation of IgA+ antibody secreting cells. Graphic Abstract
Vermicomposto na composição do substrato para produção de mudas de Schinus terebinthifolius

O objetivo do presente estudo foi analisar o efeito da adição de vermicomposto ao substrato na produção de mudas de Schinus terebinthifolius Raddi. Para isso, foram testados cinco tratamentos compostos pela adição de vermicomposto ao substrato Carolina Soil® (T1: 100% de Carolina Soil® (CS); T2: 75% de Carolina Soil® e 25% de vermicomposto (VC); T3: 50% de CS e 50% de VC; T4: 25% de CS e 75% de VC e T5: 100% de VC). Foram avaliadas as seguintes características morfofisiológicas das mudas: diâmetro do coleto (d), altura da parte aérea (h), teor de pigmentos fotossintéticos, massa seca da parte aérea (MSPA), massa seca de raízes (MSR), massa seca total (MStotal), índice de qualidade de Dickson, relação h/d e MSPA/MSR. Os dados foram submetidos à análise de variância, análise de regressão e correlação de Pearson. A correlação e a curva de resposta para o crescimento das mudas, em razão das diferentes proporções de vermicomposto e substrato comercial, mostraram que as adições de 50 ou 75% de vermicomposto foram as que mais favoreceram o crescimento das mudas de S. terebinthifolius.
Genomic and Transcriptomic Sequencing and Analysis Approaches

In this review, we explained that genomic and transcriptomic sequences and analysis assays. First of all, we detailed information of genomic and transcriptomic terms and related analyses. Genomics is aimed to elucidate the structural and functional properties of the genomes. Transcriptomics are used to express quantities of transcripts in a physiological state and specific developmental stage. The methods of genomic and transcriptomic analyses imply highly productive sequence analysis or microarray hybridization analysis as well as bioinformatics analyses. The sequencing technologies include set of methods such as preparing template, sequencing, imaging and data analysis. Firstly, the nucleotide information peculiar to DNA and RNA is obtained by means of the chosen technology in accordance with the goal and scope of the study. The obtained sequences are aligned with respect to a familiar reference sequence, or are combined as de novo . Subsequently, it is determined whether the distinct genomic sets are connected with the other genomic sets by overlapping distinct genomic sets, such as aligned sequence readings, gene annotation, EST, genetic polymorphism, and mobile elements. So, the structural variant to which the obtained sequence data are peculiar is determined. Within the scope of the study, giving information about sequencing technologies and the methods of analyses of the obtained sequences is aimed for researchers work on this subject.
Pulmonary Thromboembolism Complicating Dengue Fever—The Other Side of Dengue!

Abstract Dengue fever is a major public health concern in India with epidemics occurring periodically. Hemorrhagic complications of varying severity are described in dengue hemorrhagic fever and dengue shock syndrome. Although thrombocytopenia and hemorrhage are the much hyped complications, there is little literature on the thrombotic complications of dengue. We report a case of a 39-year-old lady who developed pulmonary thromboembolism during the first week of the illness with successful clinical outcome. The probable mechanisms of thrombosis and the treatment dilemma posed during the management of the patient are discussed.
Principe de fonctionnement de spectromètres proche infrarouge de conception récente : Near infrared - NIR

Les spectrometres proche infrarouge les plus couramment utilises type sequentiel. Cependant, de nombreux dispositifs, de conception originaie, tendent a prendre de fonctionnement de quelques systemes moins systemes multisources a base de diodes electroluminescentes, et les systemes multicanaux.
Comparative Efficacy of intra-tympanic methylprednisolone injections in different concentrations on subjective cochlear tinnitus

Introduction: Subjective tinnitus is an awareness of a phantom sound which is audible solely to the individual. Intra-tympanic steroid injections especially dexamethasone 8mg/ml have been used with variable success in relieving it; however this desired concentration is unavailable in India. The aim of this study was to assess the comparative efficacy of intra-tympanic methylprednisolone injections in different concentrations in subjective cochlear tinnitus. Materials and Methods: Ninety patients with complaint of abnormal ringing in uni/bilateral ear, with/without hearing loss were enrolled from our outpatient set-up. After written informed consent, the participants received a tinnitus loudness and frequency matching test. They were randomly assigned into three different subgroups (each with 30 patients) by a single-blind method.0. 5ml of 40mg/ml concentration methylprednisolone solution was injected intratympanically in study set one (Group A), 125mg/ml in second set (Group B) and 250mg/ml in the third set (Group C). The groups were compared in terms of subjective tinnitus intensity and loudness matching after the intervention. Results: On subjective analysis of tinnitus intensity 1 patient of Group A and 2 each of groups B and C demonstrated improvement. On loudness matching test for tinnitus, no patient in Group A was cured, though 3 each in groups B and C were cured. Conclusions : In the present study, no significant change was observed in the three treatment groups in subjective analysis of tinnitus intensity based on questionnaire. Similarly a non-significant response was obtained in loudness matching test for tinnitus. The intra-tympanic methylprednisolone injection gave suboptimal and inconsistent results at varying concentrations. Further prospective studies to evaluate the effect of intratympanic methylprednisolone on tinnitus are warranted in carefully selected group of patients. Keywords: Tinnitus, IntraTympanic Perfusion Technique, I
THE IMPACT OF FOLIC ACID SUPPLEMENTATION ON PREGNANCY

Folic Acid a water soluble vitamin (B9) serves as a fundamental cofactor in folate-intervened one-carbon digestion and in the epigenetic guideline of the translation of qualities that control neural tube closure. FA has increased significance in pregnant women because folate insufficiency has been connected with an assortment of clutters including birth imperfections and deformities in the improvement of neural tube closure. The folate supplementation also has beneficial role on pregnancy outcomes along with neural tube defects (NTD) reduction in women with seizures, preeclampsia, foetal development limitation and future chemical imbalance hazard. Whereas, over dosage of folic acid supplementation during pregnancy may be responsible for increased risk of cancers, severe adverse effects like heart problems, ectopic pregnancy and may also lead to miscarriage.
Supplementary material to "Seasonal analysis of submicron aerosol in Old Delhi using high
resolution aerosol mass spectrometry: Chemical
characterisation, source apportionment and new marker
identification"

Abstract. We present the first real-time composition of submicron particulate matter (PM1) in Old Delhi using high resolution aerosol mass spectrometry (HR-AMS). Old Delhi is one of the most polluted locations in the world, and PM1 concentrations reached ~ 600 µg m−3 during the most polluted period, the post-monsoon, where PM1 increased by 178 % over the pre-monsoon period. Using positive matrix factorisation (PMF) to perform source apportionment analysis, two burning-related factors contribute the most (35 %) to the post-monsoon increase. The first PMF factor, semi-volatility biomass burning organic aerosol (SVBBOA), shows a high correlation with earth observation fire counts in surrounding states which links its origin to crop residue burning. The second is a solid-fuel OA (SFOA) factor with links to local open burning due to its high composition of polyaromatic hydrocarbons (PAH) and novel AMS measured marker species for polychlorinated dibenzodioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). Two traffic factors were resolved, one hydrocarbon-like OA (HOA) factor and another nitrogen-rich HOA (NHOA) factor. The N compounds within NHOA were mainly nitrile species which have not previously been identified within AMS measurements. Their PAH composition suggests that NHOA is linked to diesel, and HOA to compressed natural gas and gasoline. These factors combined make the largest relative contribution to primary PM1 mass during the pre-monsoon and monsoon periods, while contributing the second highest in the post-monsoon. A cooking OA (COA) factor shows strong links to the secondary factor, semi-volatility oxygenated OA (SVOOA). Correlations with co-located volatile organic compound (VOC) measurements and AMS measured organic nitrogen oxides (OrgNO) suggest SVOOA is formed from aged COA. It is also found that a significant increase in chloride concentrations (488 %) from pre-monsoon to post-monsoon correlates well with SVBBOA and SFOA suggesting that crop residue burning and open waste burning are responsible. A reduction in traffic emissions would effectively reduce concentrations across most of the year. In order to reduce the post-monsoon peak, sources such as funeral pyres, solid waste burning and crop residue burning should be considered when developing new air quality policy.
A Transformation of the Mainland Chinese Market in Hong Kong’s Tourism Industry

ABSTRACT This paper analyzes the data of market size, profiles, and behavioral patterns of mainland Chinese tourists to Hong Kong from 1997 to 2018. With the economic boom and fewer restrictions on travel visas for mainland China, and attracted by a mixture of Eastern and Western cultures, the mainland Chinese market’s access to Hong Kong has been strengthening for the past three decades, leading to a transformation of the mainland Chinese market in Hong Kong. This paper illustrates how mainland Chinese tourists have transformed from an international tourism market to a domestic one based on market access theory. Because the mainland Chinese market will continue to be Hong Kong’s largest tourist source, more suitable travel policies should be launched for the sustainable development of tourism in Hong Kong.
Synchronization within synchronization: transients and intermittency in ecological networks

Abstract Transients are fundamental to ecological systems with significant implications to management, conservation and biological control. We uncover a type of transient synchronization behavior in spatial ecological networks whose local dynamics are of the chaotic, predator–prey type. In the parameter regime where there is phase synchronization among all the patches, complete synchronization (i.e. synchronization in both phase and amplitude) can arise in certain pairs of patches as determined by the network symmetry—henceforth the phenomenon of ‘synchronization within synchronization. ’ Distinct patterns of complete synchronization coexist but, due to intrinsic instability or noise, each pattern is a transient and there is random, intermittent switching among the patterns in the course of time evolution. The probability distribution of the transient time is found to follow an algebraic scaling law with a divergent average transient lifetime. Based on symmetry considerations, we develop a stability analysis to understand these phenomena. The general principle of symmetry can also be exploited to explain previously discovered, counterintuitive synchronization behaviors in ecological networks.
Blood profile and gut microbial load of broilers fed siam weed (Chromolaena odorata) leaf meal in their diets

Abstract The responses of 96 day old broilers fed Chromolaena odorata leaf meal (COLM) on blood profile and gut microbial load were studied for 49 days. The birds were randomly assigned to four treatment groups and replicated three times in a completely randomized design. The birds were fed four experimental diets formulated at 0%, 2%, 4% and 6% for the starter phase and 0%, 4%, 8% and 12% of COLM at the finisher phase for T1, T2, T3 and T4 respectively. All the haematological parameters were similar (P>0.05) across the treatment groups except MCH and WBC which were significantly (P< 0.05) higher and better in the treatment groups than the control group. The results on serum chemistry showed significant (P<0.05) difference for total protein, albumin, creatinine and cholesterol across the treatment groups. Cholesterol was significantly (P<0.05) reduced with increasing levels of COLM. Results showed that coliforms and E.coli were consistently higher (P<0.05) among the T1 birds than those fed T2, T3 and T4. It was concluded that, COLM enhanced adequate haematocrit and immune status, hypoglycaemic ability, suppresses the growth of gut pathogenic microorganisms and enhanced the growth of beneficial microorganism in broilers.
Plasmid transfer is biased towards close kin in bacteria from natural populations

Plasmids play a key role in microbial ecology and evolution, yet the determinants of plasmid transfer rates are poorly understood. Here we investigate the importance of genetic similarity between naturally co-occurring Escherichia coli isolates in the transfer of two plasmids (narrow-host-range R1 and broad-host-range RP4). We uncovered extensive variability, spanning over five orders of magnitude, in the ability of isolates to donate and receive plasmids. Overall, transfer was strongly biased towards clone-mates, but not correlated to genetic distance between donors and recipients. Transfer was limited by the presence of a functional restriction-modification system in recipients, thus bias towards kin might be explained by sharing of identical restriction systems. Such conjugation within lineages sets the stage for longer-term pair-wise coevolutionary interactions between plasmids and bacterial hosts.
Comprehensive analysis reveals novel gene signature in head and neck squamous cell carcinoma: predicting is associated with poor prognosis in patients

Background Head and neck squamous cell carcinoma (HNSC) remains an important public health problem, with classic risk factors being smoking and excessive alcohol consumption and usually has a poor prognosis. Therefore, it is important to explore the underlying mechanisms of tumorigenesis and screen the genes and pathways identified from such studies and their role in pathogenesis. The purpose of this study was to identify genes or signal pathways associated with the development of HNSC. Methods In this study, we downloaded gene expression profiles of GSE53819 from the Gene Expression Omnibus (GEO) database, including 18 HNSC tissues and 18 normal tissues. The differentially expressed genes (DEGs) were identified using the Linear Models for Microarray Data R package. Adjusted P values <0.01 and |log2 fold change (FC)| ≥2 was regarded as the filter condition. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of these DEGs were performed on the Database for Annotation, Visualization, and Integrated Discovery (DAVID) online website. Protein-protein interaction (PPI) network was built to visualize the interactions between these DEGs using the STRING online website. Finally, hub genes were identified by The Cancer Genome Atlas (TCGA) database. Results A total of 604 DEGs consisting of 159 upregulated genes and 445 downregulated genes were selected. From these DEGs, prognostic related genes could serve as potential biomarkers for the molecular diagnosis and therapeutic intervention of HNSC were identified. Including the known genes, GPR18, CNR2, RSPH4A, ULBP2, TEX101, and STC2. And the novel genes, CCR8, CCDC39, CNTN5, MSLN, and CHGB were strongly implicated in HNSC. Conclusions In summary, we indicated genes associated with prognostic in patients, which improve our understanding of HNSC and could be used as new therapeutic targets for HNSC.
A case report of cockayne syndrome- five cases in a single family

Cockayne syndrome (CS) is an autosomal recessive disorder caused by defect in the repair of damaged DNA. CS affects both sexes equally. CS was first reported in 1946 by the British pediatrician Cockayne as “a case with a marked decrease in growth accompanied by atrophy of the optic nerve and hearing loss. There are no indications of ethnic or racial partiality. The incidence of CS is less than 1 in 250,000 live births in the U.S. as of 1992, about 140 cases of CS had been reported in the literature. The gene responsible for CS-type I has been mapped to chromosome 5 and is called ERCC8, and for CS-type II its mapped to chromosomal locus 10q11 and is called ERCC6. A recent study showed that two-thirds of CS cases are caused by mutations in excision-repair cross complementing group 6 (ERCC6) gene while remaining cases are caused by mutations in ERCC8 gene, although the clinical symptoms are indistinguishable. CASE REPORT