Miracle-dz/UniFAR-FTUs huggingface dataset:
Pilot Scale Assessment of a Deployable Photocatalytic Treatment System Modified with BiPO4 Catalyst Particles for PFAS Destruction in Investigation-Derived Wastewaters

------------------------------------------------------------------------------------v 1. Objectives -----------------------------------------------------------------------------1 2. Background -----------------------------------------------------------------------------1 2.1. Photocatalytic Degrdation of PFAS -------------------------------------------1 2.2. Properties of BOHP and BiPO4 -------------------------------------------------2 2.3. PFAS degradation by BOHP --------------------------------------------------2 2.4. Photocatalytic reduction of PFOS ---------------------------------------------3 2.5. Slurry-based photocatalytic treatment and the Purifics Photo-cat System -3 3. Materials and Methods -------------------------------------------------------------3 3.1. Stock chemicals and syntheses -------------------------------------------------3 3.2. Instrumental analyses ------------------------------------------------------------3 3.3. Bench-top photoreactor experiments ------------------------------------------4 3.4. Photo-cat experiments -------------------------------------------------------------4 3.5. BOHP stability assessment -------------------------------------------------------5 3.6. IDW experiments -------------------------------------------------------------------5 3.7. Scale-up analysis--------------------------------------------------------------------6 4. Results and Discussion----------------------------------------------------------------6 4.1. Catalyst syntheses -----------------------------------------------------------------6 4.2. Bench-scale assessment of PFAS degradation by BOHP/UV in prepared waters ---------------------------------------------------------------------------------6 4.3. Treatment of PFAS by BOHP/UV in Photo-cat system using tap-water matrix ---------------------------------------------------------------------------------8 4.4. Treatment of IDW by BOHP/UV in Photo-cat system-----------------------10 4.5. BOHP stability assessment and TiO2 contamination-------------------------12 4.6. Scale-up analysis-------------------------------------------------------------------12 4.7. Proof-of-concept: BiPO4/UV and GaOOH/UV photocatalytic reduction of PFOS---------------------------------------------------------------------------------13 5. Conclusions and implications for future research------------------------------15 Literature Cited----------------------------------------------------------------------------17 Appendix------------------------------------------------------------------------------------19
Corrected QT Interval Prolongation Complicating Incoercible Vomiting in a Coronavirus Disease 2019 Patient Under Chloroquine and Azithromycin

Administration of chloroquine with azithromycin for the treatment of coronavirus disease 2019 (COVID-19) carries increased risk of corrected QT interval (QTc) prolongation and cardiac arrhythmias. But it is difficult to identify the real cause of QTc prolongation when two or more risk factors are gathered. This was the case of our female patient presenting with QTc prolongation after starting chloroquine and azithromycin.
Bi-Histogram Equalization Using Frequency and Spatial Technique for Digital Image Enhancement

 Abstract — Image Processing deals with analysis of image using different techniques for different purpose. Image Processing deals with the any action to change a image. Image processing has different methods like optical, analog and digital image processing. Digital image processing is a part of signal processing where we processes digital images using computer algorithms. The computer algorithms can be modified so that we can also change the appearance of the digital image easily and quickly. Many images such as medical images, remote sensing images, electron microscopy images and even real life photographic pictures, suffer from poor contrast. Therefore it is necessary to enhance the contrast. Today there are many image enhancement techniques are available. There are some drawbacks of these techniques. Adaptive histogram produces blurred and washed out images especially at the edges. Whereas alpha rooting produces over-graying enhanced images so to overcome all these drawbacks. In this proposed method we are combining the frequency domain and spatial domain techniques for image enhancement by using alpha rooting techniques with Bi-Histogram Equalization in order to enhance the quality of the image. There are many histogram equalization based methods have been introduced, many of these methods are relatively complicated in implementation, and most of Techniques require a high computational time. Bi - Histogram Equalization with Plateau Level (BHEPL) as one of the options for the system that requires a short processing time image enhancement.
CROSS-SECTION EXPECTED RETURN OF STOCKS: NEW EVIDENCE FROM THE VIETNAMESE STOCK MARKET

Previous academic papers suggested that over 300 factors have been found to explain the crosssection expected return. Moreover, findings from empirical studies also indicated that multi factor asset-pricing models such as the Fama-French three-factor model are not consistent in the context of Vietnam. This paper is conducted to examine potential factors which can explain the cross-section expected return of the Vietnamese stocks using a combination of DuPont analysis and Residual Income Valuation. With the data of 284 non-financial listed companies in Ho Chi Minh Stock Exchange during the period 2008-2014, findings from this study indicate that the return on equity and the change in return on equity are informative to cross-section stock returns. In addition, findings also present evidence to confirm that the level of capital turnover and financial cost ratio, together with the change in capital and the change in financial cost ratio contain incremental explanatory powers in explaining returns.
Newborn Transport Practices: Influence on Newborn Survival in Benin City, Nigeria

Objective: To assess the transfer process, modes of transportation, distances covered to access care, condition on arrival, and outcomes of newborns admitted to hospital in Benin City, Nigeria. Methods: This was a cross sectional survey of all consecutively presenting neonates to the children’s emergency unit over a 12-month period. Their demographic information, antepartum and perinatal antecedents, clinical information, main complaint, and co-morbidities were noted on a structured questionnaire. Other information gathered included transfer process, mode of transport, distance covered to reach facility, interventions during transport, condition on arrival, and outcome. Data were analyzed using descriptive statistics, frequencies, and chi-square comparisons; significance was set at P<0.05. Results: Responsible persons for 115 babies—73 males and 42 females—completed the questionnaire. Of the newborns, 62 (53.9%) were of normal birth weight and 43 (37.3%) of low birth weight; of these 37 (32.2%) were preterm. Most cases arrived from peripheral hospitals without referral notes or prior contact with the receiving hospitals. There was no organized pre- or intra-transfer stabilization or medical interventions. Patients came mainly with relatives (89%) or healthcare workers (10%). They arrived in private cars (81%), and were not kept in warm clothes. Distance covered was 10-20 km for more than 50% and over 100 km for less than 8%. Perinatal asphyxia was the commonest reason for transfer (14%). Lower gestational age and cyanosis on presentation significantly affected survival, as only 13 of 25 (52%) with cyanosis and 23 of 37 (62.2%) preterm babies survived. Overall mortality was 30/ 115 (26.1%), and preterm mortality was significantly higher at 14/37 (37.8%). Conclusions: The neonatal transfer process is poorly developed. Prior contact with receiving hospitals is infrequent. Staffing, monitoring, and stabilizing interventions during transfer of sick newborns are inadequate. Transfer mode might have affected survival of preterm infants in particular.
PD-1 inhibitor combined with apatinib for advanced gastric or esophagogastric junction cancer: a retrospective study

Background Nivolumab and pembrolizumab were approved as immune checkpoint inhibitors for third-line treatment of advanced gastric or esophagogastric junction cancer (GC/EGJC) in 2017. However, immunotherapy monotherapy has low efficacy. Apatinib has been proven effective in advanced GC/EGJC. Numerous studies have shown that immunotherapy has a synergistic effect when combined with targeted drug therapy. Based on these facts and to assess the efficacy and safety of programmed death 1 (PD-1) inhibitor and apatinib as combination therapy in patients (pts) with unresectable locally advanced or metastatic GC/EGJC, a retrospective clinical research study was carried out. Methods Pts (n=24) received PD-1 inhibitor and apatinib (250 mg once daily) as second- or third-line therapy in this observational, retrospective study. The primary objectives were efficacy and safety. Results At data cut-off (December 31, 2019), 24 pts were enrolled. Of the 19 pts who were evaluable, the objective response rate (ORR) was 26.3% (5/19), the median progression-free survival (PFS) was 3.0 (95% CI: 1.3 to 4.7) months, and the median overall survival (OS) was not reached. Grade 3 or 4 treatment-related adverse events (TRAEs) occurred in 3 (15.8%) of the 19 pts. These adverse events (AEs) included pruritus, rash, hand-foot syndrome, and increased aspartate aminotransferase (AST) or alanine aminotransferase (ALT). No treatment-related deaths occurred. Conclusions Combination therapy of PD-1 inhibitor and apatinib showed encouraging clinical activity and demonstrated tolerable toxicity in pts with advanced GC/EGJC. Hence, our work provide rationale for the combination of PD-1 inhibitor and apatinib in advanced GC/EGJC.
Current Status of Vilazodone

Vilazodone is a serotonin transporter (SERT) and a partial agonist of HT1A. It has been approved by food and drug administration of United States (US FDA) for the treatment of major depressive disorder (MDD) in adults. This agent is considered as a new class of drug “serotonin partial agonist and reuptake inhibitor (SPARI)” by the World Health Organization (WHO). The authors planned to review the drug by using the key word of “vilazodone” on different data base and synthesize a working theory regarding the mechanism of selective serotonin reuptake inhibitor (SSRI) mediated serotonergic neurotransmision. The review also focuses on 5-HT1A autoreceptors. Due to its novel mechanism of action, initially it gave hope to the clinicians and researchers as majority of depressive patients are partial responders or treatment resistant to previously available antidepressants. But later research works suggested that the vilazodone is not much different than the drug available in market. Its side effects were found to be lower than other antidepressant but higher than placebo. It can be concluded that more comparative research between vilazodone and other antidepressant is required in making better opinion about this drug.
Earthquake Resistant Design of Reinforced Concrete Buildings Past and Future

This paper briefly reviews the development of earthquake resistant design of buildings. Measurement of ground acceleration started in the 1930s, and response calculation was made possible in the 1940s. Design response spectra were formulated in the late 1950s to 1960s. Non-linear response was introduced in seismic design in the 1960s and the capacity design concept was generally introduced in the 1970s for collapse safety. The damage statistics of reinforced concrete buildings in the 1995 Kobe disaster demonstrated the improvement of building performance with the development of design methodology. Buildings designed and constructed using out-dated methodology should be upgraded. Performance-based engineering should be emphasized, especially for the protection of building functions following frequent earthquakes.
PML-RARα interaction with TRIB3 impedes PPARγ/RXR function and triggers dyslipidemia in acute promyelocytic leukemia

Although dyslipidemia commonly occurs in patients with acute promyelocytic leukemia (APL) in response to anti-APL therapy, the underlying mechanism and the lipid statuses of patients with newly diagnosed APL remain to be addressed. Methods: We conducted a retrospective study to investigate the lipid profiles of APL patients. PML-RARα transgenic mice and APL cells-transplanted mice were used to assess the effects of APL cells on the blood/liver lipid levels. Subsequently, gene set enrichment analysis, western blot and dual luciferase reporter assay were performed to examine the role and mechanism of PML-RARα and TRIB3 in lipid metabolism regulation in APL patients at pretreatment and after induction therapy. Results: APL patients exhibited a higher prevalence of dyslipidemia before anti-APL therapy based on a retrospective study. Furthermore, APL cells caused secretion of triglycerides, cholesterol, and PCSK9 from hepatocytes and degradation of low-density lipoprotein receptors in hepatocytes, which elevated the lipid levels in APL cell-transplanted mice and Pml-Rarα transgenic mice. Mechanistically, pseudokinase TRIB3 interacted with PML-RARα to inhibit PPARγ activity by interfering with the interaction of PPARγ and RXR and promoting PPARγ degradation. Thus, reduced PPARγ activity in APL cells decreased leptin but increased resistin expression, causing lipid metabolism disorder in hepatocytes and subsequent dyslipidemia in mice. Although arsenic/ATRA therapy degraded PML-RARα and restored PPARγ expression, it exacerbated dyslipidemia in APL patients. The elevated TRIB3 expression in response to arsenic/ATRA therapy suppressed PPARγ activity by disrupting the PPARγ/RXR dimer, which resulted in dyslipidemia in APL patients undergoing therapy. Indeed, the PPAR activator not only enhanced the anti-APL effects of arsenic/ATRA by suppressing TRIB3 expression but also reduced therapy-induced dyslipidemia in APL patients. Conclusion: Our work reveals the critical role of the PML-RARα/PPARγ/TRIB3 axis in the development of dyslipidemia in APL patients, potentially conferring a rationale for combining ATRA/arsenic with the PPAR activator for APL treatment.
Development and Evaluation of Tablets Containing Powders of Benincasa Hispida and Murraya Koenigii : A Novel Anti-Diabetic Product

Diabetes mellitus is a group of metabolic disorders of fat, carbohydrate and protein that results from defects in insulin secretion, insulin action or both. Diabetes mellitus is reported with a reduced life expectancy, morbidity, health complication and overall drop in quality of life. The International Diabetes Federation predicted a huge rise in diabetic population in coming years. Treatment of Diabetes involves diet control, exercise, use of insulin and oral hypoglycemic drugs. The existing treatment options are reported with ineffectiveness against long term Diabetes mellitus complications, side effects and rise in cost. Studies made on plant parts reported with enormous possibilities of treating Diabetic mellitus with formulations containing natural ingredients. The effectiveness, lack of side effects and low cost is making plant based anti-diabetic products popular across the world. The study attempts to develop oral anti-diabetic tablets containing plant based materials as active ingredients and major excipients. The developed product may overcome the drawbacks of existing synthetic anti-diabetic agents. Along with safety, better management of Diabetes mellitus may be possible with the proposed product.
Towards Real-time Webcam-based Attention Tracking in Online Learning

A main weakness of the Massive Open Online Learning movement is retention: a small minority of learners (on average 5-10%, in extreme cases <1%) that start a MOOC complete it successfully. There are many reasons why learners are unsuccessful, among the most important ones is the lack of self-regulation: learners are often not able to self-regulate their learning behavior. Designing tools that provide learners with a greater awareness of their learning is vital to the future success of MOOC environments. Detecting learners’ loss of focus during learning is particularly important, as this can allow us to intervene and return the learners’ attention to the learning materials. One technological affordance to detect such loss of focus are webcams—ubiquitous pieces of hardware available in almost all laptops today. Recently, researchers have begun to make use of webcams as part of complex machine learning-based solutions to detect inattention or loss of focus based on eye tracking and eye gaze data. However, those approaches tend to have a high detection lag, are inaccurate, and are complex to design and maintain. In contrast, in this paper, we explore the possibility to make use of simple metrics such as gaze presence or face presence to detect a loss of focus in the online learning setting. To this end, we evaluate the performance of three consumer and professional eye-tracking frameworks using a benchmark suite we designed specifically for this purpose: it contains a set of common xMOOC user activities and behaviours. The results of our study show that already those simple metrics pose a significant challenge to current hardand software-based eye-tracking solutions. Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than the author(s) must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from permissions@acm.org. IUI’18, March 07–11, 2018, Tokyo, Japan © 2018 Copyright held by the owner/author(s). Publication rights licensed to ACM. ISBN 123-4567-24-567/08/06. $15.00 DOI: http://dx.doi. org/10.475/123_4 ACM Classification
Incidence and Trends of Ischemic Heart Disease and Coronary Revascularization Procedures in Gaza: A Descriptive Retrospective Study

Background: We investigated the results of diagnostic coronary angiography and trends in rates of myocardial revascularization procedure included percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) procedures in Gaza between 2015 and 2018. Methods: A descriptive retrospective study based on the analysis of all diagnostic coronary angiographies (CAG) based on the largest Ministry of Health hospital in Palestine AlShifa Hospital Report and the Center of Bureau of Statistics, to evaluate the annual rate of PCI and CABG volume have been done since January 2015 until January 2019. Results: A total of 4887 diagnostic coronary angiography procedures were performed. The mean age of patients was 58.0±10.2 years. A 3245 of cases were male (66.4%). A total of 5225 revascularization procedures (PCI: 4286, CABG: 939) were performed during the study period. From 2014 to 2018 the PCI volume increased by 94 % (80/100 000 to 155/100 000) (P < 0.0001), CABG volume decreased by 47 % (30/100 000 to 17 /100 000) (P <0.0001), PCI/CABG ratio increased from 2.7 to 9.1 (P< 0.0001). The indications for diagnostic coronary angiography were stable angina (57% of cases), non-ST-elevation acute coronary syndrome (NSE-ACS) in 24.0%, ST-elevation myocardial infarction (STEMI) in 19.0%. The diagnostic coronary angiography results showed significant lesions in 64.5% of patients. About 19.2% of total cases have three vessel disease, 21% have two vessel disease and 24.4% of them have one vessel disease. The segments most involved were Left Anterior Descending Artery (LAD) which was involved in 47.2% of cases. Discussion: We observed a dramatic increases in the total coronary revascularization procedures with a marked decrease in CABG and increase in PCI procedures in Gaza.
Do infant rats cry

In the current revival of interest in the emotional and mental lives of animals, many investigators have focused attention on mammalian infants that emit distress vocalizations when separated from the home environment. Perhaps the most intensively studied distress vocalization is the ultrasonic vocalization of infant rats. Since its discovery, this vocalization has been interpreted both as a communicatory signal for the elicitation of maternal retrieval and as the manifestation of emotional distress. In contrast, the authors examined the cardiovascular causes and consequences of the vocalization, and on the basis of this work, they hypothesized that the vocalization is the acoustic by-product of the abdominal compression reaction (ACR), a maneuver that results in increased venous return to the heart. Therefore, the vocalization may be analogous to a sneeze, serving a physiological function while incidentally producing sound.
Aerodynamic Optimization of Supersonic Transport Wing Using Unstructured Adjoint Method

In the application of gradient-based methods to practical aerodynamic design problems, one of the major concerns is an accurate and efficient calculation of sensitivity derivatives of an aerodynamic objective function. Sensitivity derivatives can be evaluated robustly and efficiently by using a sensitivity analysis code based either on a direct method or on an adjoint method. An adjoint method is preferable in aerodynamic designs because it is more economical when the number of design variables is larger than the total number of an objective function and constraints.
MASSIVE MIMO: IMPLEMENTATION AND ITS CHALLENGES

- Massive MIMO (Ma-MIMO) is a promising technology that increases the capacity of a specific radio link by increasing the number of antennas at the transmitter and receiver side. This ensures effective utilization of multipath propagation with an increase in spectral and power efficiency. The design and implementation of Ma-MIMO faces a lot of challenges in many aspects. This review paper focuses on the potential challenges in architecture, detection algorithms used and its performance analysis.
Extended-spectrum β-lactamases and bacterial resistance

Objective To investigate the incidence of extended spectrum β lactamases (ESBLs) of E.coli and K. pneumoniae in Hua Shan Hospital of Shanghai Medical University and their relationship with antibiotic resistance patterns.Methods ESBLs producing strains in E.coli and K. pneumoniae were detected by double disc synergy test, inhibitor potentiated disc diffusion test and inhibitor combined with minimum inhibitory concentrations (MIC) determination of third generation cephalosporins. The bacterial susceptibility testing of ESBLs producing strains was assayed by Kirby Bauer method.Results The incidence of ESBLs was 25% in E.coli and 57% in K. pneumoniae. ESBLs producing strains were more resistant to third generation cephalosporins and aztreonam, but few of which was resistant to imipenem. The susceptibility rate of these strains to cefoxitin was about 80%. Most strains were resistant to amikacin and ciprofloxacin.Conclusion Extended spectrun β lactamases play a most important role in bacterial resistance to third generation cephalosprins and monobactams. We should pay much attention to detecting ESBLs producing strains and their susceptibility to antibiotics.