Miracle-dz/UniFAR-FTUs huggingface dataset:
More Than a Caring Personality: Factors Affecting Staff Retention in Non Profit Organisations in Ireland

Non Profit organisations pursue social missions in providing services to marginalised groups. People attracted to this work usually wish to ‘make a difference’ and available research highlights their attachment to fulfilling the organisational mission. This article seeks to understand factors affecting retention as explored with front-line Project Workers in homeless services. The current socio-economic context in Ireland has heightened pressure in these services due to resource shortages alongside increasing demand. In these circumstances, relying excessively on mission attachment can result in burnout and turnover. This article seeks to identify other factors which motivate employees including organisational culture, management and personnel policies. The findings show that employee’s’ employment experience is mediated primarily through social relationships. When human resource policies are brought to life through organisational culture and management approaches, workers feel supported to continue this demanding work and thus maximise the benefit of this extremely valuable resource – staff - to their organisations.
Properties of Single Calcium‐activated Potassium Channels of Large Conductance in Rat Hippocampal Neurons in Culture

Patch‐clamp recordings were made on rat hippocampal neurons maintained in culture. In cell‐attached and excised inside‐out and outside‐out patches a large single‐channel current was observed. This channel had a conductance of 220 and 100 pS in 140 mM [K+]i/140 mM [K+]o and 140 mM [K+]i/3 mM [K+]o respectively. From the reversal potential the channel was highly selective for K+, the PK+/Pna+ ratio being 50/1. Channel activity was voltage‐dependent, the open probability at 100 mM [Ca2+]i increasing by e‐fold for a 22 mV depolarization. It was also dependent on [Ca2+]i at both resting and depolarized membrane potentials. Channel open states were best described by the sum of two exponentials with time constants that increased as the membrane potential became more positive. Channel activity was sensitive to both external (500 μM) and internal (5 mM) tetraethylammonium chloride. These data are consistent with the properties of maxi‐K+ channels described in other preparations, and further suggest a role for maxi‐channel activity in regulating neuronal excitability at the resting membrane potential. Channel activity was not altered by 8‐chlorophenyl thio cAMP, concanavalin A, pH reduction or neuraminidase. In two of five patches lemakalim (BRL 38227) increased channel activity. Internal ruthenium red (10 μM) blocked the channel by shortening the duration of both open states. This change in channel gating was distinct from the ‘mode switching’ seen in two patches, where a channel switched spontaneously from normal activity typified by two open states to a mode where only short openings were represented.
Algebraic and Graphic Languages for OLAP Manipulations

This article deals with multidimensional analyses. Analyzed data are designed according to a conceptual model as a constellation of facts and dimensions, which are composed of multi-hierarchies. This model supports a query algebra defining a minimal core of operators, which produce multidimensional tables for displaying analyzed data. This user-oriented algebra supports complex analyses through advanced operators and binary operators. A graphical language, based on this algebra, is also provided to ease the specification of multidimensional queries. These graphical manipulations are expressed from a constellation schema and they produce multidimensional tables.
Semantic-free attributes for image classification

Attributes are defined as mid-level image characteristics shared among different categories. These characteristics are suitable in order to handle classification problems especially when training data are scarce. In this paper, we design discriminative real-valued attributes by learning nonlinear inductive maps. Our method is based on solving a constrained optimization problem that mixes three criteria; the first one aims to predict real-valued attributes with a high precision while the second criterion maximizes their discrimination power. We also consider a particular smoothness term that provides gradual representations for data belonging to the same categories, resulting into highly discriminant and predictable attributes. Experiments conducted for the particular task of fine-grained image classification - with relatively small training sets - show that our attribute design approach is very competitive and outperforms related attribute learning methods.
Grepafloxacin Concentration in Ocular Tissues after Intravenous Infusion in Rabbits with Intraocular Inflammation

Purpose: To determine the penetration of grepafloxacin into ocular tissues during experimental ocular inflammation. Methods: 10 albino and 10 pigmented rabbits underwent a continuous intravenous infusion of the drug 24 h after injecting Salmonella typhimurium toxin intravitreously, creating ocular inflammation. The animals were killed and grepafloxacin levels were determined in plasma and ocular tissues using high performance liquid chromatography. Results: Grepafloxacin levels achieved a steady-state plasma concentration of 1.5 µg/ml. The drug diffused more towards vascularized tissues (chorioretina and iris) in both albino and pigmented rabbits with a tissue/serum ratio higher than 1. Grepafloxacin showed more affinity to pigmented tissue, rising levels of 40,000–50,000 ng/g in the chorioretina and iris in pigmented animals. After inflammation, grepafloxacin intraocular penetration increased in albino animals with levels exceeding the minimum inhibitory concentration for the most common ocular pathogens. Conclusion: Grepafloxacin intraocular penetration is higher in pigmented tissues. Ocular inflammation increases the drug penetration into the vitreous.
Event-triggered dynamic L2 controller design for linear systems with quantized feedback

This paper investigates the finite-gain L2 stability problem based on event-triggered quantized feedback control for linear systems by using dynamic output-feedback controller. A time delay system method is adopted to deal with the periodic event-triggered control system. Sufficient event-triggered conditions to guarantee the finite-gain L2 stability of the system with exogenous disturbances have been proposed in terms of linear matrix inequalities when an infinite-level logarithmic quantizer is utilized. Besides, a quantizer of finite levels is designed associated with the event conditions, by which an ultimate boundedness of the closed-loop system can be achieved. Moreover, the explicit expression of the dynamic controller has been given. Finally, a numerical example is presented to show the feasibility and efficiency of the theoretical results.
ASPIRE: Adaptive Service Provider Infrastructure for VANETs

ASPIRE: Adaptive Service Provider Infrastructure for VANETs Agop Koulakezian Master of Applied Science (M.A.Sc.) Graduate Department of Electrical and Computer Engineering University of Toronto 2011 User desire for ubiquitous applications on-board a vehicle motivates the necessity for Network Mobility (NEMO) solutions for Vehicular Ad-Hoc Networks (VANETs). Due to the dynamic topology of VANETs, this approach incurs excessive infrastructure cost to maintain stable connectivity and support these applications. Our solution to this problem is focused on a novel NEMO-based Network Architecture where vehicles are the main network infrastructure. Within this Architecture, we present a Network Criticality-based clustering algorithm, which adapts to mobility changes to form stable self-organizing clusters of vehicles and dynamically builds on vehicle clusters to form more stable Mobile Networks. Simulation results show that the proposed method provides more stable clusters, lower handoffs and better connectivity compared to popular densitybased vehicle clustering methods. In addition, they confirm the validity of the proposed Network Architecture. The proposed method is also robust to channel error and exhibits better performance when the heterogeneity of vehicles is exploited.
A 2.45-GHz Vivaldi Rectenna for the Remote Activation of an End Device Radio Node

A 2.45 GHz rectenna consisting of a modified Vivaldi antenna with a broadside radiation and an half-wave series voltage multiplier is presented. The dc voltage provided by the proposed rectenna is used in a wireless sensor network to remotely enable an end device radio node. Reported experimental data demonstrate an operation distance of ~ 70 cm with an enabling signal of 130 mW.
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Currently governments worldwide are taking advantage of technological tools now have to improve all government processes, allowing us to have more direct contact with citizens, providing in the information. The whole process described above corresponds to a constant evolution called Open Government or o-Gov, releasing all their information to individuals and allowing data to be open and available at any time (Open data). That consists of publishing its information to the general citizenry, allowing the data to be accessible at any time (Open data). Is why, if you work with these open data should be targeted at knowledge discovery aspect that is not applying the current governments. Therefore, this article aims to expose the shortcomings presented by these governments, not progressing toward an open government that applies knowledge discovery processes.
Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA

The regulated binding of effector proteins to the nucleosome plays a central role in the activation and silencing of eukaryotic genes. How this binding changes the properties of chromatin to mediate gene activation or silencing is not fully understood. Here we provide evidence that association of the budding yeast silent information regulator 3 (Sir3) silencing protein with the nucleosome induces a conformational change in the amino terminus of histone H4 that promotes interactions between the conserved H4 arginines 17 and 19 (R17 and R19) and nucleosomal DNA. Substitutions of H4R17 and R19 with alanine abolish silencing in vivo, but have little or no effect on binding of Sir3 to nucleosomes or histone H4 peptides in vitro. Furthermore, in both the previously reported crystal structure of the Sir3-bromo adjacent homology (BAH) domain bound to the Xenopus laevis nucleosome core particle and the crystal structure of the Sir3-BAH domain bound to the yeast nucleosome core particle described here, H4R17 and R19 make contacts with nucleosomal DNA rather than with Sir3. These results suggest that Sir3 binding generates a more stable nucleosome by clamping H4R17 and R19 to nucleosomal DNA, and raise the possibility that such induced changes in histone–DNA contacts play major roles in the regulation of chromatin structure.
Portfolio Selection Efficient Diversification Of Investments

portfolio selection efficient diversification of investments is available in our book collection an online access to it is set as public so you can download it instantly. Our digital library spans in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Merely said, the portfolio selection efficient diversification of investments is universally compatible with any devices to read.
Age‐dependent variations in the expression of PLC isoforms upon mitogenic stimulation of peripheral blood T cells from healthy donors

The activation of phosphoinositide‐specific phospholipase C (PLC) is one of the early responses to various growth factors and it is known that these functions are altered with ageing. In the present investigation, the expression and cellular distribution of PLC isoenzymes in immunocompetent T lymphocytes from a test group of healthy individuals over 65 years old and a comparison group of healthy donors below 30 years old were compared using Western blot and confocal microscopy. All lymphocyte samples responded biochemically to phytohaemagglutinin (PHA) stimulation, as shown by at least 10‐fold increases in the β3 isoform and nuclear translocation of the β1, β2, β3, β4, γ1 and γ2 isoforms; however, consistent differences in the expression of the β2 isoform in unstimulated T cells and of the β2 and γ2 isoforms in stimulated T cells suggest that altered functions of the PLC pathway may have an age‐dependent impact on signal transduction events.
A SCALE TO MEASURE PERCEIVED RISK IN E-LEARNING ADOPTION

Perceived risk is known as one of the most important barriers in technology adoption. However, there is less literature analyzing perceived risk in relation with e-learning adoption. The present study aims to develop a scale to measure perceived risk in e-learning. The relevance of such research is motivated by the utility of such a measurement instrument, which allows to educational institutions to assess perceived risk before implementing an e-learning system. The level of perceived risk directly influences the level of e-learning acceptance among students. The methodology used in this study is appropriate to a quantitative approach. The sample was formed by 154 undergraduate business students which were interrogated about the risks they would perceive if they could enroll in an online Master’s program. Scale reliability analysis and factor analysis were used to test instrument. Further research should concentrate on acquiring validity for the scale and testing stability over time.
Supplementary frequency control mechanism to ensure reliability of power system: Based on an international comparison

In this paper, as a part of comprehensive frequency control mechanism, the supplemental frequency control mechanisms to stabilize the power system during severe contingencies has been presented. From the regulatory, operational and technical perspective, a worldwide international practice among the different countries also has been discussed. In general, for resourceful countries, adequate operating reserve including spinning & non-spinning can restore system frequency within the shortest possible time frame. But, for a developing country with high energy demand and limited fuel resources, during severe contingencies an additional frequency control mechanism is also required to avoid cascading blackout. In this paper, based on international practice and considering developing countries electricity market a four layer supplemental frequency control mechanism is proposed. These four layer mechanisms — reserve, contingency-based load shedding, under frequency load shedding and islanding can be added on grid code with the alignment of policy.
High vitamin D3 requirements in broilers for bone quality and prevention of tibial dyschondroplasia and interactions with dietary calcium, available phosphorus and vitamin A

1. Two experiments were carried out to investigate responses in performance and bone compositional and structural characteristics in broilers fed diets containing 4 concentrations of vitamin D3 (5, 20, 125 and 250 µg cholecalciferol/kg) at different concentrations of calcium, available phosphorus and vitamin A. 2. In experiment 1, body weight and tibia breaking strength were maximised at 14 d with 250 µg vitamin D3/kg, tibia ash was maximised with 125 µg vitamin D3/kg. A high incidence of tibial dyschondroplasia (TD) was decreased to very low levels with 125 µg vitamin D/kg. 3. At 42 d, performance and bone characteristics showed no response to vitamin D3 concentrations above 20 µg/kg. 4. Dietary vitamin A within the range 2·4 to 4·5 mg retinol/kg did not show any interaction with vitamin D3 status at either age. 5. In experiment 2, responses to vitamin D3 were strongly influenced by dietary calcium/available phosphorus. With 13 g calcium and 5 g available phosphorus/kg, performance and bone characteristics responded to vitamin D3 concentrations up to 125 µg/kg but more was needed at less optimal concentrations of calcium and available phosphorus. TD incidence was minimised with 250 µg/kg. 6. This study shows that high dietary concentrations of vitamin D3 can prevent TD. It is concluded that the vitamin D3 requirement of broilers up to 14 d of age at optimal dietary calcium and available phosphorus concentrations may be in the range 35 to 50 µg/kg for cortical bone quality and up to 250 µg/kg for prevention of TD. The vitamin D3 requirement for cortical bone quality after 14 d is not higher than 20 µg/kg. These requirements are much higher than earlier estimates and may be related to higher calcium requirements of modern broiler genotypes. Current regulations limiting maximum vitamin D3 concentrations in broiler starter diets may need to be reviewed.
Caffeine impact on neonatal morbidities

Caffeine is a silver bullet in neonatology. This ubiquitous trimethylxanthine, pervasively used in the human diet and beverages, significantly impacts on major acute neonatal morbidities including apnea of prematurity, bronchopulmonary dysplasia, patent ductus arteriousus with or without surgical ligation and post-operative apnea. Potential uses in respiratory distress syndrome as suggested by improved lung function in primate models is supported by the decreased time on mechanical ventilation and need for oxygen therapy. Improved later outcomes at 18 to 22 months include clinically significant decreases in cerebral palsy, cognitive impairment, and severe retinopathy of prematurity in those babies who received caffeine during the neonatal period compared to non-caffeine treated placebo neonates. Ongoing and future research studies focus on optimizing current dose regimens to determine whether benefits can be maximized while maintaining an impressive safety profile. Molecular pharmacologic studies focused on the molecular and the biochemical mechanisms underlying the protective effects of caffeine are also being done to optimize treatment regimes and to target potential molecular pathways leading to further decreases in acute and long term neonatal morbidities. Since its use in newborns three decades ago, caffeine is now one of the safest, most cost-beneficial and effective therapies in the newborn.
MANAGEMENT BUYOUTS: DISTINGUISHING CHARACTERISTICS AND OPERATING CHANGES PRIOR TO PUBLIC OFFERING

This is a two-part study of management buiyouts. In the first part we identify characteristics of firms bought out by their management by contrasting a sample of 65 firms which went private between 1980 and 1987 with an industry-matched comparison group of 130 firms. Firms which go private, when compared with others in their industries, tend to have higher levels of cash flow as a percentage of sales, have lower levels of receivables to sales, and have a significantly higher incidence of takeover speculation prior to the buyout. In the second part of the study we find that privately held firms, in the 3 years preceding the public offering, grow faster in revenues than their corresponding industry averages, while maintaining a better performance than industry norms in inventory management, in accounts receivable, and in operating income. In particular, private firms originating through management buyouts of divisions (of publicly held corporations) exhibit substantially higher growth rates than their industry averages, while still maintaining the same levels of operating income. These findings collectively suggest heightened performance after management buyout, which may be attributable to the changed governance structure of the firm.
A comparison of Au and Ag metalized layer in microstructured optical fibers for surface plasmon resonance excitation

Plasmons on the surface of large metalized holes containing analyte are excited by the fundamental mode of a microstructured fiber. Phase matching between Plasmon and core modes is facilitated by the perforation of fiber core. A comparison of Au and Ag metalized layer is illustrated. There are some differences between gold and silver layer in SPR excitation ability and strength.
Surface Electromyographic Signals Using Dry Electrodes

For many electromyography (EMG) applications, a suitable dry electrode would simplify practical implementation of an EMG recording system. Wearable mobility monitoring is an example of such a system. Therefore, surface EMG signals, from Fraunhofer Institute for Biomedical Engineering (IBMT) flexible dry electrodes and Orbital Research electrodes, were compared to signals from conventional Ag/AgCl electrodes. EMG measurements were performed on the right tibialis anterior for a range of different activities, such as light twitches, isometric contractions, jumping, and walking. Signal feature comparisons, skin preparation effects (i.e., cleaning with isopropyl alcohol), and impedance-noise analyses were performed. Results showed that both dry electrodes had comparable sensitivity to the standard Ag/AgCl electrodes for detecting small unloaded muscle contractions and large loaded contractions. Results also showed that noise content and impedance are weakly correlated and skin preparation methods did not have a positive effect on skin/electrode impedance.
Performance evaluation of a 3GPP LTE terminal receiver

In this paper we present the evaluation of a receiver signal processing chain for a 3GPP long term evolution (LTE) terminal, including coarse synchronisation, channel estimation, fine syncronisation (tracking), MIMO equalization and detection. Algorithm blocks are first individually explained and simulatively evaluated with a realistic channel model. Adjustments of the blocks to each other for improved robustness are described, like interaction between time synchronization and channel estimation performance. After joint optimization, the performance of the complete chain is evaluated. Practical tradeoffs between complexity and performance are investigated and low-complexity algorithms are used. The presented receiver achieves an implementation loss of about 2 dB compared to perfect synchronization and channel estimation conditions.
A gene encoding sn‐glycerol 3‐phosphate dehydrogenase (NAD+) complements an osmosensitive mutant of Saccharomyces cerevisiae

Osmoregulatory mutants of Saccharomyces cerevisiae with a defect in their capacity to readjust the cell volume/buoyant density after osmotically induced dehydration were enriched by density gradient centrifugation. Colonies derived from cells that remained dense after dehydration were screened for sensitivity to high concentrations of NaCl and defects in their osmotically induced production and intracellular accumulation of glycerol. The isolated osg (osmosensitive gtycerol defective) mutants were recessive in heterozygous diploids and fell into four complementation groups (osg1‐osg4). The osg1‐1 mutant, described in this work, is unable to grow at low water potential and shows a decreased capacity for glycerol production and a strongly reduced activity of NAD+‐dependent sn‐glycerol 3‐phosphate dehydrogenase (GPD), an enzyme in the glycerol‐producing pathway. Complementation of the osg1‐1 salt sensitivity defect with a low copy yeast genomic library led to the cloning of GPD1, encoding an S. cerevisiae GPD consisting of 391 amino acids and sharing 47‐50% identity with GPD from other sources. Micro‐sequencing of the N‐terminus of purified S. cerevisiae GPD revealed a 20‐amino‐acid sequence that was identical to a nucleotide‐deduced amino acid sequence in GPD1, but indicated that the enzyme is produced with an N‐terminal extension that is removed from the functional enzyme. Subcellular fractionation does not indicate, however, that the putative pre‐sequence targets GPD to any organelle; the enzyme appears to be located in the cytoplasm. Chromoblot and tetrad analysis were used to position the GPD1 gene to chromosome IV, with a distance of about 18 cM from trp1.