Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of fat inclusion on diet digestibility in growing rabbits.

Fifty-six California x New Zealand rabbits were used to study the influence of fat addition on nutrient digestibility. Seven diets were formulated to a 24% ADF level: Diet C had no added fat; Diets T, O, and S contained 3% of added beef tallow, oleins, and soybean oil, respectively; and Diets TWS, OWS, and SWS contained the same level and types of fat but also 18% heated whole soybean meal (WS) to increase dietary ether extract (EE) by 3%. After the digestibility trial, rabbits (weighing 2.00 +/- .13 kg) were slaughtered to determine the composition of cecal contents. Fat addition increased digestibility of energy (P < .05) and EE (P < .001). The type of fat only affected (P < .05) EE digestibility. No interaction between fat types and WS was found. Although EE levels of cecal contents increased in diets with added fat (P < .001), they did not negatively affect dietary fiber digestibility. The patterns of fatty acid digestibility in Diet C and in those with soybean oil (S and SWS) were similar; the lowest values were obtained for C16:0 and C18:0. The digestibility of unsaturated fatty acids of C18 increases as its degree of unsaturation increases. Digestibilities of C16:0 and C18:2 were, respectively, lower and higher in the diet with 3% soybean oil than in the diet with 3% tallow. (ABSTRACT TRUNCATED AT 250 WORDS)
DD No . 10 / 05 Does Export Pricing Explain ‘ Fear of Floating ’ in Small Open Emerging Market Economies ?

Trade data on East Asian EMEs shows the predominant use of Dollar Currency Pricing (DCP). Using a DSGE model with six-stage vertical production chain, staggered prices, and crossborder trade in intermediate inputs, we aim to provide an alternative explanation for fear of oatingby EMEs. We examine interactions between rmspricing rules and the transmission of external shocks under di¤erent exchange rate regimes. We nd that weak input substitution and DCP of exports eliminate expenditure-switching and the allocative role of exchange rate adjustment, resulting in exchange rate dis-connect, and hence fear of oatingby EMEs. JEL classi cation: E31; E52; F41
University Bean Collection in the Prospect of Nutritional Research

Current experimental program has been carried out in order to determine the outputs of crop rotation in mountain and steppe areas in the outskirts of Almaty. The main morphogenetic characters have been studied by implying the collection of common beans, Phaseolus vulgaris L composed of several samples from such countries as Kazakhstan, China, Czech Republic, Poland, Turkey, Russia and USA, generated under different climate and soil conditions. A series of useful genetic resources displaying major economically valuable traits were identified. Several introduced cultivars of common bean have revealed proper seed emergence rate, suitable maturation and significant resistance to the water scarcity [1,2]. Some Kazakhstani varieties have been shown to surpass foreign specimens and cultivars by the seed weight and other parameters. It has been indicated that cv. “Luna” from Czech collection would get maturation the first (80 days from planting to complete technical maturity), whereas the rest of cultivars have been recorded to rich the same conditions a decade later [3]. Local specimen “Aktatti” has manifested its response to the effect of new bio-organic mineral fertilizer synthesized by the Faculty of Chemistry [4]. Basic catalogue of common bean resources including approximately 40 parental cultivars and accessions of Phaseolus vulgaris L and their relatives originally from different geographic regions has been compiled [5]. The data have been completed by quantitative and qualitative amino acid analysis. Kazakhstani and external cultivars and specimens respectively have been subdivided by the data on amino acid composition of seeds further tested by liquid chromatography. Essential amino acids have been determined to set up approximately 30% of the total content of amino acids among Kazakhstani specimens [6]. If tyrosination index (Phe/Tyr ratio) for external varieties was equal to 0.88-0.89, local specimens have shown the similar index to be around 0.90-0.95. This difference may emphasize the role of powerful membrane proteins in strengthening domestic lines by a composite stability (resilience, temperature and metabolic) when compared to international common bean specimens under investigation [7]. Following research on domestic bean collection in terms of the application of another developing branches of bean biology and biotechnology is considered to require special attention of researchers and authorities in charge [8].
A ug 2 01 5 More on Rotations as Spin Matrix Polynomials

Any nonsingular function of spin j matrices always reduces to a matrix polynomial of order 2j. The challenge is to find a convenient form for the coefficients of the matrix polynomial. The theory of biorthogonal systems is a useful framework to meet this challenge. Central factorial numbers play a key role in the theoretical development. Explicit polynomial coefficients for rotations expressed either as exponentials or as rational Cayley transforms are considered here. Structural features of the results are discussed and compared, and large j limits of the coefficients are examined.
Relationship between depression and substance use disorders in adolescent women during the transition to adulthood.

OBJECTIVES To examine the continuity of substance use disorder (SUD) in adolescent women during the transition to adulthood and to assess psychosocial functioning associated with SUD. Furthermore, to examine concurrent and longitudinal relationships' between major depressive disorder (MDD) and SUD during this developmental transition. METHOD One hundred fifty-five women, aged 17 to 19 years, were recruited from 3 high schools and were followed annually for 5 years. Comprehensive diagnostic and psychosocial assessments were performed with standardized instruments. The primary outcome measures included MDD and SUD during follow-up in those with and without a prior history of MDD or SUD, and psychosocial functioning associated with SUD. RESULTS The 5-year incidence of SUD was 9.6% and, by the end of follow-up, 18.7% had a lifetime episode. Prior SUD significantly increased the risk for SUD diagnosis during the study. Co-occurrence of MDD and SUD was high during adolescent and early adult years, with episodes of both disorders occurring in close temporal proximity. SUD also predicted MDD over time, but the reverse was not true. After controlling for the effects of MDD on social adjustment, SUD was associated with significant impairment in school functioning. CONCLUSIONS These results suggest that the risk for new onset and recurrence of SUD is high during the developmental transition to adulthood. SUD during this developmental period is associated with significant school-related problems. The findings also suggest that SUD and MDD frequently co-occur during the post-high school transition in women. Given the significant psychosocial dysfunction associated with these illnesses, early detection of these problems and effective intervention are crucial.
A Case Report of Cavernous Hemangioma as a Cause of Occult Gastrointestinal Bleeding

This is a descriptive study based on the case report of a patient suspected of occult gastrointestinal bleeding who was evaluated by the gastroenterology service in Clínica Nuestra in Cali. Previous studies had not shown cause of bleeding. Video endoscopy (Mirocam) found a lesion in the small intestine. Enteroscopy at performed at Clínica Farallones in Cali with an Olympus 180 Q enteroscope confirmed the finding. Surgery further confirmed the diagnosis. Data and photographs were obtained from the database of endoscopy services and the pathology photos were obtained from the pathologist’s registry. A literature review based on a Pubmed search of the existing literature on clinical histories and reports of similar cases is included.
Treatment of Resistant Influenza Virus Infection in a Hospitalized Patient with Cystic Fibrosis with DAS181, a Host-Directed Antiviral

We report a cystic fibrosis patient infected with influenza 2009H1N1 who had persistent viral shedding and clinical deterioration despite prolonged treatment with oseltamivir and zanamivir. The patient was diagnosed with H275Y neuraminidase inhibitor resistant influenza during treatment, thus was treated for 10 days with DAS181, an investigational host-directed inhaled sialidase fusion protein. Viral clearance occurred after 5 days of therapy and the patient became eligible for lung transplantation. Although the patient succumbed prior to receiving a transplant, this case exemplifies the potential utility of a host-directed approach against influenza which has potential to become resistant to neuraminidase inhibitors.
(forthcoming in Noûs)

In this paper we address the question of what determines the content of our conscious episodes of thinking, considering recent claims that phenomenal character individuates thought contents. We present one prominent way for defenders of phenomenal intentionality to develop that view and then examine ‘sensory inner speech views’, which provide an alternative way of accounting for thought-content determinacy. We argue that such views fare well with inner speech thinking but have problems accounting for unsymbolized thinking. Within this dialectic, we present an account of the nature of unsymbolized thinking that accords with and can be seen as a continuation of the activity of inner speech, while offering a way of explaining thought-content determinacy in terms of linguistic structures and representations. 1. The indeterminacy problem: phenomenal intentionality vs. naturalistic programs In recent years, the phenomenal intentionality program has garnered interest within the philosophical debate surrounding intentionality. Phenomenal intentionality is intentionality that can be attributed to a mental state, purely in virtue of its phenomenal character (Kriegel, 2014: 2). Different views of how to describe and explain such intentionality stress, in one way or another, a close connection to (phenomenal) consciousness: the so-called ‘inseparatism’ claim (Horgan and Tienson, 2002). Such views offer a new perspective on the question of content determinacy, that is, on what it is that warrants a certain content of a mental state and not some other: phenomenal character plays this role in explaining intentionality. These views are typically contrasted with naturalistic approaches to intentionality which attempt to explain
Bird community structure and population trends in the Little Carpathians Mts vineyard area

Puchala, P., 2016. Bird community structure and population trends in the Little Carpathians Mts vineyard area. Folia Oecologica, 43: 42–49. The birds of the vineyards on the eastern slopes of the Little Carpathians Mountains (south-western Slovakia) were studied during breeding seasons between the years 2010 and 2015. A point census method was used to count birds once or twice in May on two study sites (a transect in the vicinity of Modra town and a transect between Bratislava-Rača and Svätý Jur). The whole study area was designated as an Important Bird Area and established as a Special Protected Area according to the Bird Directive. Individual counting points were situated in different habitats including suburban areas, green lines with scrubs, the edges of small forest patches, forest edges, small gardens, cultivated vineyards, etc. 62 and 53 bird species were found in the first and the second transect, respectively (64 birds in total). The total number of all individuals was 2,383 at the Modra site and 972 at the Rača-Svätý Jur site. The most abundant species on both transects was Sturnus vulgaris (21 and 36%, respectively). Another abundant species at the Modra site (dominance between 5 and 7%) were Turdus merula, Passer montanus, Passer domesticus and Delichon urbicum, while at the RačaSvätý Jur site Fringilla coelebs and Apus apus were abundant. Several species with higher conservation importance were found: Upupa epops, Lullula arborea, Pernis apivorus, Jynx torquila, Lanius collurio and Sylvia nisoria. A decline of some species like Chloris chloris, Delichon urbicum, Emberiza citrinella, Fringilla coelebs, Saxicola torquata, Sylvia atricapilla and Upupa epops was recorded since the beginning of the study. Continuous and long-term monitoring may bring important data about the population status of birds in human-affected landscape.
Observation of Helicoverpa armigera Hübner ( Lepidoptera : Noctuide ) Infestation on Gladiolus grandiflorus ( Iridaceae ) in Çanakkale

Helicoverpa armigera (Hübner), the cotton bollworm, is the serious and commonly known pest in agricultural areas in the world. In this study, H. armigera was reared at 23±2°C, 65% RH and 16:8 h L:D in the laboratory on leaves and flowers of Gladiolus grandiflorus. The eggs were laid singly on the upperside of the G. grandiflorus leaves. There were 5 larval stages based on molts and head capsule measurements. The development of larvae was completed in an average of 16.75 ± 4.13 days and the survival rate was 64.1%. In this study, developmental period of larval stages, adult fecundity and pupal sex differentiation were determined on the ornamental host of the pest.
Relation of erythrocyte Na+-K+ ATPase activity and cholesterol and oxidative stress in patients with type 2 diabetes mellitus.

BACKGROUND Diabetic patients are at high risk of atherosclerotic complications, and factors associated with this include hypercholesterolemia, hemorheologic disturbances in erythrocytes and oxidative stress. We, therefore, carried out a study in type 2 diabetic patients to determine the relationships of erythrocyte Na+-K+ ATPase activity, plasma cholesterol and oxidative stress in this population. METHODS Erythrocyte Na+-K+ ATPase activity and its relationship between plasma cholesterol and thiobarbituric acid reactive substance (TBARS, a marker of oxidative stress) were studied in type 2 diabetic patients with (n = 26) or without angiopathy (n = 30). Na+-K+ ATPase activity was measured by a colorimetric enzymatic method. Plasma TBARS levels were determined spectrophotometrically. Diabetic patients were classified according to plasma cholesterol concentrations as normo- or hypercholesterolemic (plasma total cholesterol > 5.18 mmol/L). RESULTS Diabetic patients with or without angiopathy had lower erythrocyte Na+-K+ ATPase activity (p < 0.001 and p < 0.001 respectively) and higher plasma TBARS levels than healthy subjects (n = 20) (p < 0.001 and p < 0.001 respectively). Na+-K+ ATPase activity in the diabetic patients with angiopathy was lower than in the diabetic patients without angiopathy (p < 0.001). In the diabetic patients both with and without angiopathy, hypercholesterolemic patients had lower erythrocyte Na+-K+ ATPase activity and higher plasma TBARS levels than normocholesterolemic patients (p < 0.001, p < 0.001 respectively) There was no difference in the plasma TBARS concentrations between diabetic patients with and without angiopathy. There were negative correlations between erythrocyte Na+-K+ ATPase activity and both plasma cholesterol (r = -0.72) and plasma TBARS (r = -0.46) and a positive correlation between plasma cholesterol and TBARS (r = 0.42). CONCLUSIONS Elevated plasma cholesterol may be responsible for the inhibition of erythrocyte Na+-K+ ATPase activity. Together with elevated cholesterol, free radical-induced mechanisms may be involved in the inhibition of Na+-K+ ATPase activity.
Research on the Factors Affecting Non-Performing Loan of Chinese Commercial Bank

The rise of non-performing loans has weakened the core competitiveness of commercial banks, and also hindered the reform and innovation of China's banking industry and the stable operation of the macro economy. Therefore, researching the problem of non-performing loans has its theoretical and practical significance. This paper selected 10 listed Banks as research objects, adopted the panel data from the first quarter of 2012 to the third quarter of 2018, and explored the influencing factors of the non-performing loan ratio through the multiple regression model. The conclusions have been shown as follows:(1) PMI, bank provision coverage and net interest margin have a significant negative impact on non-performing loans;(2) total loans have a significant positive impact on non-performing loan ratio. The research shows that the government's macro-control and bank management can be put forward to prevent and dispose of China's commercial Banks non-performing loans.
DESIGN METHODOLOGIES FOR 25 GHz SPACED RZ-DPSK SYSTEMS OVER CONVENTIONAL NZ-DSF SUBMARINE CABLE

In order to increase the capacity of existing submarine cable systems costeffectively, upgrade methodologies are discussed considering various fibre types, modulation formats, bit-rates, and FEC. As an example of an upgrade scenario, 25 GHz spaced 10 Gbps RZ-DPSK over legacy fibre was closely investigated. The experimental results showed excellent Q performance over the whole waveband after 8,329km transmission. However the Q performance around a system’s zero-dispersion region is degraded as the periodic dispersion compensation length reduces. In addition, 40 Gbps RZ-DQPSK transmission around a system’s zero-dispersion region is examined. These results suggest that nonlinear phase matching between the signals and ASE probably plays the primary role in the zerodispersion region, resulting in a strong dependency on the dispersion map. The possibility of electrical dispersion compensation at the transmitter and receiver is also discussed.
Asteroid and comet impacts: the ultimate environmental catastrophe

Cosmic impacts represent the most extreme class of natural hazards, combining a very low probability of occurrence with a capability of killing hundreds of millions and destabilizing global civilization. Fortunately, these disasters are amenable to precise prediction and even (in principle) can be avoided entirely by appropriate application of space technology. However, impacts take place so rarely that they have only recently been recognized as a significant natural hazard. Concerted international action to deal with impacts depends on increased public awareness.
Is patellar denervation circumferentially effective in reducing anterior knee pain and improving knee function after total knee arthroplasty ? A meta-analysis of randomized controlled trials

The aim of this meta-analysis was to evaluate whether patellar denervation with electrocautery (PD) without resurfacing after total knee arthroplasty (TKA) had an advantage over no patellar denervation (NPD) regarding postoperative anterior knee pain (AKP) and knee function. The electronic databases including PubMed, Embase, Web of Science and the Cochrane Library were systematically searched up to June 2017. Four hundred and eleven papers were identified and 8 randomized controlled trials containing 881 knees (796 patients) were finally eligible for meta-analysis. GRADE approach was used to assess the overall quality of evidence. The pooled results showed that PD could reduce the incidence of AKP and improve WOMAC score in early period (within 12 months) (P=0.0001), but not maintain after 12 months follow-up (P=0.12). In addition, we found better knee functional outcomes in range of motion (ROM) (P=0.02) and Knee Society Score knee score (KSSKS) (P=0.002) and the results did not change over time. We also identified PD was associated with better Oxford Knee Score (OKS) after 12 months follow-up. However, there was no significant difference between the two groups in visual analogue scale score (VAS), patella score (PS), and other outcomes. Based on this meta-analysis of all currently published RCTs, the findings have important implications for the medical community, namely, that PD is a safe procedure to reduce the incidence of AKP in early period and improve the knee function with similar rates of adverse events compared with NPD.
Development of an immunochromatographic strip for antibody detection of pseudorabies virus in swine

An immunochromatographic strip was developed for the serological detection of pseudorabies virus (PRV) in swine. In the strip, the expressed protein of gB, one of the glycoproteins of PRV, labeled with colloidal gold, was used as the detector; staphylococcal protein A and swine anti–pseudorabies virus antibody were blotted on nitrocellulose membrane for the test and control lines, respectively. The specificity of the strip was 98.1%, and the sensitivity of the strip with reference anti-PRV serum was 96.0%. Swine serum samples (296) were collected to evaluate the characteristics of the strip in comparison with an existing commercial kit. The agreement was 93.6%. Furthermore, the dipstick assay based on the strip is rapid (5 min) and easy to perform with no requirement of professional skills, reagents, or equipment. This suggests that the immunochromatographic strip is an acceptable alternative for use in clinical laboratories lacking specialized equipment and for field diagnosis.
Dasatinib attenuated bleomycin-induced pulmonary fibrosis in mice

Abstract Anti-fibrotic effect of dasatinib, a platelet-derived growth factor receptor (PDGFR) and Src-kinase inhibitor, was tested on pulmonary fibrosis (PF). Adult mice were divided into four groups: mice dissected 21 d after the bleomycin (BLM) instillation (0.08 mg/kg in 200 µl) (I) and their controls (II), and mice treated with dasatinib (8 mg/kg in 100 µl, gavage) for one week 14 d after BLM instillation and dissected 21 d after instillation (III) and their controls (IV). The fibrosis score and the levels of fibrotic markers were analyzed in lungs. BLM treatment-induced cell proliferation and increased the levels of collagen-1, alpha smooth muscle actin, phospho (p)-PDGFR-alpha, p-Src, p-extracellular signal-regulated kinases1/2 and p-cytoplasmic-Abelson-kinase (c-Abl) in lungs, and down-regulated PTEN expression. Dasatinib reversed these alterations in the fibrotic lung. Dasatinib limited myofibroblast activation and collagen-1 accumulation by the inhibition of PDGFR-alpha, and Src and c-Abl activations. In conclusion, dasatinib may be a novel tyrosine and Src-kinase inhibitor for PF regression in mice.
Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents

The emergence of resistance to existing antibiotics demands the development of novel antimicrobial agents directed against novel targets. Historically, bacterial cell wall synthesis, protein, and DNA and RNA synthesis have been major targets of very successful classes of antibiotics such as β-lactams, glycopeptides, macrolides, aminoglycosides, tetracyclines, rifampicins and quinolones. Recently, efforts have been made to develop novel agents against validated targets in these pathways but also against new, previously unexploited targets. The era of genomics has provided insights into novel targets in microbial pathogens. Among the less exploited – but still promising – targets is the family of 20 aminoacyl-tRNA synthetases (aaRSs), which are essential for protein synthesis. These targets have been validated in nature as aaRS inhibition has been shown as the specific mode of action for many natural antimicrobial agents synthesized by bacteria and fungi. Therefore, aaRSs have the potential to be targeted by novel agents either from synthetic or natural sources to yield specific and selective anti-infectives. Numerous high-throughput screening programs aimed at identifying aaRS inhibitors have been performed over the last 20 years. A large number of promising lead compounds have been identified but only a few agents have moved forward into clinical development. This review provides an update on the present strategies to develop novel aaRS inhibitors as anti-infective drugs.