Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification of Medication Related Problems During Medication Reviewsin A Community Setting

Objective: Medication reconciliation is the process of collecting a list of a patient’s medications including name, dosage, frequency, and route of administration. Medication reconciliation is important to reduce the risk of drug-related problems and is a National Patient Safety Goal. The objective of this study was to evaluate a pharmacist-performed medication reconciliation process to identify the pharmacist’s contribution in identifying high-risk patients, identifying medication-related problems (MRPs) and potential adverse drug events, and recommending alternative treatments to prevent MRPs. Methods: This study was a cross-sectional analysis in an ambulatorycare clinic. Patients included in the analysis were taking at least 7 medications with at least 2 disease states, and had an appointment with a clinic provider from July to September 2013. The primary outcome was the number and type of MRPs encountered during pharmacist-performed medication reconciliations. We also identified patient factors associated with MRPs and provider acceptance of recommendations. Results: Fifty-three patient visits were analysed. On average, 8 MRPs were found per visit. Patients saw an average of 8 providers in the 15 months preceding their visit. A total of 477 MRPs were addressed by the pharmacist, including 309 medication errors and 22 adverse drug events. The most common MRPs included the patient taking medications not on provider’s list (26%), discontinued medication on medication record (21.7%), and no monitoring for disease state or medication (12.8%). A statistically significant increase in the number of MRPs was found in patients taking greater than 10 medications (5 vs 9; p = 0.044) and those who saw at least 7 providers (7 vs 10; p = 0.02). Providers approved 74% of pharmacist recommendations. Conclusions: Pharmacist-performed medication reconciliations resulted in a significant number of MRPs being identified and resolved.
The realisation of voicing assimilation rules in Hungarian spontaneous and read speech: Case studies

Hungarian represents a particularly fruitful ground for exploring voicing assimilation. Although this topic has been extensively analysed, a contradiction can be observed between most phonological descriptions and acoustic-phonetics-based studies of voicing assimilation. Theoretical works suggest that this process in Hungarian speech is a purely regressive, obligatory and categorical phenomenon, but in practice divergent realisations can be observed. In the present paper three case studies of voicing assimilation are performed. CCC clusters, CC clusters interrupted by pause and partially voiced realisations were analysed. The results showed that in the first two cases the speech planning process and the degree of self-monitoring were the most influential factors, while the various concomitances of voicing and devoicing arising due to aerodynamic and articulatory reasons resulted in partially voiced realisations. The variability of the data confirms the hypothesis that Hungarian voicing assimilation is a g.
Life Cycle of Tree Frogs (Hyla savygnyi) in Semi-Arid Habitats in Northern Israel

The life cycle of tree frogs (Hyla savygnyi) in localities of various habitats in northern Israel in the Upper Galilee and Golan Heights (annual rainfall range of 500-1,000 mm) and the Hula Valley, ranging from 212 to 740 m above sea level (ASL), was studied. Tree frogs were observed around winter rain pools, springs and streams. Fifty-one different breeding places were monitored. Only ponds and springs having stable non-flowing water are used by tree frogs for reproduction and are where larvae can metamorphose. The male call in the breeding places attracts the female, who then comes to the male, and breeding occurs underwater. Breeding time in Israel varies according to location and geographical and ecological conditions. It takes place in March-April in northern Israel, the Upper Galilee, the Golan Heights and the Hula Valley. In various breeding places, larvae grow between April and June. Apparently tree frog larvae adapt to breeding places where stable water is found, such as in ponds or springs, but not to breeding places with flowing water such as streams or rivers. Various Anuran and Urodela larvae were found in the same breeding sites where the larvae of H. savygnyi were found, including Pseudepidalea Viridis, Rana bedriagae, Pelobates syriacus, Salamandra infraimmaculata and Triturs vittatus. Following metamorphosis, H. savygnyi adapt to terrestrial life in semi-arid habitats, and is found on plants or in hiding places under rocks and in holes to prevent dehydration particularly during hot and dry weather. The ability to change color helped the frogs to hide in various substrates. The rate of water loss of terrestrial H. savygnyi during dehydration is around 50% of body weight. Plasma osmolality increased from 200 mOsm/kg to about 450 mOsm/kg, which helped the tree frog to survive in semi-arid habitats.
Systematic Risk and Credit Ratings

Investors were surprised during the Global Financial Crisis that mortgage securitizations were exposed to larger default rates than corporate bonds given the same credit rating. This paper presents a parsimonious model attributing deviations of default rates from expected default probabilities implied by credit ratings to systematic risk. Conditions, under which the systematic risk of securitized tranches of pools is higher than that of single name debt instruments with the same rating are identified. An extensive empirical study analyzes a unique and comprehensive data set, which includes ratings, yield spreads, defaults and control variables for securitizations and corporate bonds. The analysis finds evidence that financial instruments may be exposed to different levels of systematic risk given the same rating. Therefore, credit ratings do not provide comprehensive information on the degree of systematic risk. An analysis of yield spreads at origination finds empirical evidence that fixed income investors (contrary to credit rating agencies) include systematic risk in the pricing of financial instruments. JEL classification: G20; G28; C51
In-situ investigation of pulsed corona discharge

High voltage pulses are created with spark gap switched circuits to create positive corona streamer discharges. The pulse voltage rise time is in the order of tens of nanoseconds and its duration is less than one microsecond to avoid breakdown. The corona discharge is investigated with electrical and in-situ optical techniques to determine the energy per pulse and the behaviour of the discharge. The highest energy per pulse is 9 J per meter anode length. The discharge stucture is determined with Schlieren photo's and CCD images, the number of streamers is always 4-7 cm·'. The streamer diameter is determined with the CCD camera and is found to be 200 pm. Emission spectroscopy is used to determine the gas temperature, which remains close to room temperature, and the electron energy, which is 10 eV in the streamer head, 1 eV in the secondary streamer and 0.5 eV in the residual streamer channel. The discharge is used to remove NO from gas mixtures and flue gas. The best cleaning efficiency observed is 50% or 125 ppm NO removal at an energy input of 6 Wh/Nm , this result is obtained with short electrical pulses (20 ns) and a high gas' humidity (10%). Models for the streamer propagation and the chemical reaction kinetics are described and are shown to be in qualitative agreement with the measurements.
The Travel Cost Demand Model as an Environmental Policy Assessment Tool: A Review of Literature

Estimates of the benefits of environmental improvement, usually a nonmarket commodity, can be a valuable part of the information base for economically efficient environmental decision making. The objective of this paper is to review the literature of one class of nonmarket valuation methodologies based on observed consumption behavior subsumed under the term "travel cost demand models. " Relative to travel cost demand models, we examine policy issues and underlying concepts focusing on choice theory and welfare evaluation. In addition, we identify major related empirical issues including demand specification, data problems, demand estimation, and welfare measurement. Unanswered questions may contribute to a research agenda.
CONTINUOUS DEPENDENCE ESTIMATES FOR VISCOSITY SOLUTIONS OF FULLY NONLINEAR DEGENERATE ELLIPTIC EQUATIONS

Using the maximum principle for semicontinuous functions [3, 4], we prove a general “continuous dependence on the nonlinearities” estimate for bounded Hölder continuous viscosity solutions of fully nonlinear degenerate elliptic equations. Furthermore, we provide existence, uniqueness, and Hölder continuity results for bounded viscosity solutions of such equations. Our results are general enough to encompass Hamilton-Jacobi-Bellman-Isaacs’s equations of zero-sum, two-player stochastic differential games. An immediate consequence of the results obtained herein is a rate of convergence for the vanishing viscosity method for fully nonlinear degenerate elliptic equations.
Physicochemical Characteristics and Sugar-snap Cookie Potentialities of Korean Wheats

Physicochemical properties and suitability of domestic wheat varieties for production of sugar-snap cookie were examined. Four kinds of commercially available wheat flour and six kinds of other domestic wheat varieties were tested. Domestic wheat varieties had protein contents ranging 7.7 to 11.5%, alkaline water retention capacity (AWRC) of 54.6 to 65.2%, Pelshenke values of 17 to 31 min, and sedimentation values of 19.6 to 30.8 mL. Peak viscosity range of Korean wheat flours measured by Rapid Visco Analyser was from 134.4 to 346.3 unit. Diameter of cookies for US soft wheat flour was 7.8 cm and domestic wheat flours ranged from 7.2 to 7.9 cm. Cookie spread factors for Alchanmil, Tapdongmil, and Woorimil flours were higher than those of other flours. Protein content had significantly high correlation coefficient of r = 0.892** with sedimentation value, and showed negative correlation with cookie diameter, spread factor, and top grain score. AWRC values had significantly high correlation coefficient of r = −0.736** with cookie diameter. Spread factor of cookie showed positive correlation with top grain score.
Pyramid of Maslahah for Social and Economic Welfare:The Case of Bank Islam Malaysia Berhad

Islamic financial system is no longer a new phenomenon. The existence of Islamic banking over the past fifty years has proven that Islamic financial system has a stand and desirable by society. Maqasid shari’ah or the higher objective of shari’ah is viewed by the contemporary Muslim bankers and academicians as an alternative tool to emphasize on issues relating to social and economic ends of financial transactions. Instead of over emphasizing on profit maximization in conventional banking, the Maqasid shari’ah mechanism contributes to the reorientation of Islamic finance and banking. This is seen in the social welfare institution process of innovation as promoted by Islamic moral economy. Islamic economy suggested the establishment of Islamic social banking in order to fulfil the social and economic needs of the Muslim. Thus, Islamic financial institutions (IFIs) focus is mainly on the social and economic welfare, benefits, and needs. Moral values is the major mutual concern of the system, neither profit maximization nor competitiveness as practiced by existing finance and banking system. This paper shed light on the prospects of pyramid of maslahah in social and economic welfare area of IFIs such as the practice of charity, waqf , zakat and Takaful. Bank Islam being the pioneer Islamic bank in Malaysia is chosen in assessing their role on promoting social and economic welfare as outlined by maqasid shari’ah . Keywords: Islamic financial system, social and economic welfare, maqasid shari’ah , social banking
Methods of Analysis (Extraction, Separation, Identification and Quantification) of Carotenoids from Natural Products

Developing techniques for isolation and identification of biocompounds, from natural products, resulted in a rapid enrichment of carotenoid pigments number. For their isolation from biometabolites mixtures, the physical and chemical properties are taken into account. Carotenoids are sensitive to light, heat, oxygen, acids and alkaline bases. The exposure to light (direct sunlight/ UltraViolet), causes cis–trans photoisomerization, which may lead to their photodestruction. Biological materials containing carotenoids and their solutions must be protected from the action of light. Many carotenoids are thermolabile (xanthophylls); their heating being indicated only when it is absolutely necessary. The separation of carotenoids is done at room temperature or up to –20°C, in the dark. In the case of hot saponification they should be protected by a low–boiling solvent (30–60°C). Carotenoids may be oxidized in the presence of oxygen or peroxides, because of their sensitivity to oxygen in the adsorbed state (in thin layer or column chromatograms). It is necessary to operate in inert conditions (under nitrogen or vacuum). The oxidation during the extraction and saponification can be minimized if it is carried out in a nitrogen atmosphere. The exposure of carotenoids to acids, leads to changes such as: the oxidative decomposition, cis–trans isomerization and isomerization of 5,6–epoxides and 5,8–epoxides. The inconveniences are minimized by neutralization (calcium carbonate, pyridine, dimetilalanine). It works with purified solvents, freshly distilled, chlorinated derivatives (dichloromethane or solvents containing hydrochloric acid). The storage of carotenoids should be done in the dark, under an atmosphere of nitrogen or in vacuum, at a temperature of –20°C. The best preservation method is in the crystalline state. The current research techniques are using spectral methods, which provide accurate information on the structure and properties of organic biosubstances. Compared to chemical methods of identification, spectral methods have the advantage that it provides data faster, are accurate, require small amounts of material and enable continuous analysis at different stages of processing of the compound extracted without changing the composition of the biosubstance investigated, which enables its recovery. This chapter presents the main methods of extraction, separation and identification of organic compounds with direct applications on carotenoids.
Safety and Tolerability of Edivoxetine for Long-Term Treatment of Major Depressive Disorder in Adult Patients

This 12-month open-label, but dose-blinded extension phase, evaluated the safety and tolerability of flexibly-dosed edivoxetine (6, 9, 12 or 18 mg once daily) in patients (N = 397) with major depressive disorder, who completed the 10-week randomized, double-blind, placebo-controlled acute phase of the study.All patients were treated with edivoxetine during the extension phase. The mean age of the patients was 45 years, and most were white females. Safety evaluations included assessment of treatment-emergent adverse events (TEAEs), laboratory and vital sign measures, and suicidality. Within-group t-tests based on a 2-sided significance level of 0.05 and 95% confidence levels were used to assess whether changes from baseline were statistically significant from zero. The overall completion rate was 54%. Adverse event was the most common (14.4%) reason for discontinuation, which included blood pressure increased (1.3%), heart rate increased (1.3%), anxiety (1.0%), and tachycardia (1.0%). At least 1 TEAE was reported by 72.3% of patients, of which headache (10.8%) and hyperhidrosis (10.1%) were the most common; 2.8% of patients had ≥1 serious adverse events, and there were no completed suicides. No clinically relevant changes were observed in most laboratory measures. Potentially clinically significant changes in ALT values occurred in 1.8% of patients, and either normalized or had decreased by the last assessment. Mean increases in blood pressure and pulse were consistent with those observed in the acute phase and appeared to reach a plateau within 3 to 5 months of treatment. In conclusion, safety and tolerability findings during this long-term extension phase evaluation of edivoxetine were consistent with its norepinephrine reuptake inhibition profile.
Original Sin and Procylical Fiscal Policy: Two Sides of the Same Coin?

The paper develops a simple model of sovereign debt where default both through direct repudiation and through inflation are possible and give rise to (endogenous) constraints on the currency composition and the level of public debt. This set up allows to show that procyclicality of fiscal policy in EMEs can arise as a by-product of the "original sin" and both can be explained by the presence of weak monetary institutions which cannot commit to price stability. The paper suggests that, as monetary institutions in EMEs strengthen, the "original sin" would fade away and the cyclical properties of fiscal policy would improve.
Nonlinear Feature Extraction for Hyperspectral Images

In this study non-linear dimension reduction methods have been applied to a hyperspectral image in order to increase the classification accuracy in feature extraction step. Furthermore, image segmentation has been ensured the by taking into consideration the spatial synthesis of hyperspectral images and passing from high-dimensional space to low dimensional space. It has been compared the results obtained from the image segmentation made by taking one pixel from this spatial synthesis. The advantages of the effects of the results of the dimension reduction techniques made by facing neighbor pixels on the segmentation of hyper-spectral image have been displayed in the experimental results part.
TRANSCRIPTOMIC CHANGES IN RUMINAL TISSUE INDUCED BY THE PERIPARTURIENT TRANSITION IN DAIRY COWS

To understand how the capacity for fat metabolism (uptake, synthesis, modification) changes in rumen epithelia immediately before and after onset of lactation in dairy cows, rumen fluid Short Chain Fatty Acid (SCFA) concentrations and mRNA expression profiles of rumen epithelia was determined in twelve Holstein dairy cows at three weeks prior to calving (wk -3, n = 12), one week post calving (week +1, n = 12) and six weeks (week +6, n = 12) after calving. The diet was modified from a dry cow formulation to a lactating cow formulation immediately following parturition and raised the non-fiber carbohydrate level from 34 to 43%. All data was analyzed using the mixed procedure of SAS, with cows blocked by anticipated calving date and week of sampling as the repeated measure. Propionate, butyrate, isovalerate and valerate levels rose significantly following the diet change (p≤0.001), although acetate and isobutyrate levels were unchanged (p>0.05). Mean rumen pH also changed during the transition period (6.38 Vs 5.81 and 5.85±0.08; -3 Vs +1 and +6; p
Potential item set mining by using utility pattern growth model in big data

Information extracted by using data mining in earlier days. Now a day’s, the most talked about technology is Big Data. Utility Mining is the most crucial task in the real time application where the customers prefer to choose the item set which can yield more profit. Handling of large volume of transactional patterns becomes the complex issue in every application which is resolved in the existing work introducing the parallel utility mining process which will process the candidate item sets in the paralyzed manner by dividing the entire tasks into sub partition. Each sub partition would be processed in individual mapper and then be resulted with the final output value. The time complexity would be more when processing an unnecessary candidate item sets. This problem is resolved in the proposed methodology by introducing the novel approach called UP-Growth and UP-Growth+ which will prune the candidate item sets to reduce the dimension of the candidate item sets. The time complexity is further reduced by representing the candidate item sets in the tree layout. The test re-sults prove that the proposed new approach provides better result than the existing work in terms of accuracy.
A Chaotic System with an Infinite Number of Equilibrium Points: Dynamics, Horseshoe, and Synchronization

Discovering systems with hidden attractors is a challenging topic which has received considerable interest of the scientific community recently. This work introduces a new chaotic system having hidden chaotic attractors with an infinite number of equilibrium points. We have studied dynamical properties of such special system via equilibrium analysis, bifurcation diagram, and maximal Lyapunov exponents. In order to confirm the system’s chaotic behavior, the findings of topological horseshoes for the system are presented. In addition, the possibility of synchronization of two new chaotic systems with infinite equilibria is investigated by using adaptive control.
Determinants of Rural Households’ Poverty with Selected Link Functions: The Case of Soro District, Hadiya Zone, SNNPR States, Ethiopia

Poverty is a general feature in Ethiopia causing many sufferings to the largest proportion of the population. This study assessed the determinants of rural household poverty in five selected kebeles in Soro district by using the generalized linear modeling approach. With the specific objectives of estimating rural households’ poverty status, identifying appropriate link function, and identifying determinants of rural households’ poverty. Primary data were obtained through structured questionnaire interview. A total of 184 selected sample households were identified by proportional allocation. Based on the primary data whereby set of consumption food energy-intake method the probability of being poor was assessed. By using national poverty line of 2200 kcal, out of total of 184 sample households surveyed 65.76% were found to be poor. Log-log link function is found to be more appropriate to fit the data. Model adequacy diagnostic tests of the cook’s distance and GLM residuals shows that there were no outliers and influential values that had significant impact on the model results. Based on generalized linear model results, the major determinants of rural households’ poverty were age of household heads, family size per adult equivalent, access to credit service, dependency ratio, TLU, access to health service, and number of oxen ownership. Hence, promoting equitable economic growth, family planning, increasing land productivity, increasing credit service, increasing health service, increasing TLU and promoting research extension farmer linkage are indispensable policy interventions to better reduce rural poverty.
Ethanolic Extract of Caesalpinia bonducella f. Seed Ameliorates Diabetes Phenotype of Streptozotocin- Nicotinamide-Induced Type 2 Diabetes Rat

Caesalpinia bonducella F. (Leguminosae) is widely used medicinal plant which contains flavonoid, tannin, saponin, and a potent antioxidant activity. However, the antihyperglycemic effect of the seed of C. bonducella is remained to be evaluated. This study used 24 male Wistar albino rats that were induced for type 2 diabetes with streptozotocin (STZ) and nicotinamide (NA). The rats were divided into three groups: the distilled water-treated group (NC group), glibenclamide-treated group (10 mg/kg/d, oral; PC group), and C. bonducella seed extract-treated group (500 mg/kg/d, oral; T group). Blood glucose and plasma insulin measurements were done after 14 days of treatment. The results showed that the postprandial blood glucose (PPBG) level of both PC and T groups were decreased significantly (p < 0.01 for both), whereas in NC group, the PPBG level was rising (p < 0.01). Glibenclamide was found to be more effective to decrease the PPBG level than C. bonducella seed extract (p < 0.01). The post-test fasting insulin level of T group was higher than other groups (p < 0.05). In summary, our results suggest that ethanolic extract of C. bonducella seed possesses antidiabetic activity against experimentally-induced type 2 diabetes.