Miracle-dz/UniFAR-FTUs huggingface dataset:
Sistema autónomo de detección y almacenamiento de errores por sucesos aislados en SRAMs

En esta contribucion se explica el diseno, fabricacion y verificacion experimental de un sistema automatico de lectura y escritura de memorias SRAM cuyo objeto es la determinacion de la tasa de errores asociados a la accion de los rayos cosmicos e impurezas radiactivas en esa tecnologia de fabricacion. Se ha concebido este sistema para que se pudiera construir en una placa de reducidas dimensiones y que, de este modo, pudiera transportarse en la cabina de un avion durante vuelos comerciales.
Living in Thin Air: New Fruit Fly Research Pinpoints Genomic Hallmarks of Human High Altitude Adaptation.

Twenty-one percent, that is the amount of oxygen in the air that we breathe—with the exception of the extreme high-altitude dwellers on the Tibetan or Andean mountains. To get at the genetic roots of these thin air thrivers, a collaborative research team led by University of Chicago Professor Kevin White and University of California San Diego’s Jha et al. 2015 turned to a research workhorse, the fruit fly and identified a treasure trove of new genes—all told, over 100 genes that may be critical to high-altitude adaptation, with more than 40 similar genes found in humans. The results were published in the advanced online edition of Molecular Biology and Evolution. Using experimental evolution followed by whole-genome sequencing (dubbed “evolve and resequence”), the research team grew three fruit fly populations under severely hypoxic conditions over many generations. Sequencing the hypoxiatolerant flies (surviving on just 5% oxygen by the 13th generation) they identified 3,800 single mutations many of which mapped within 66 genomic regions and prioritized a total of 99 candidate fruit fly genes. Many of these were primarily associated with development of respiratory system in fruit flies. In addition, gene knockdown experiments of the targets significantly enhanced survival under severe hypoxic conditions. “In a tribute to legendary Sherpa mountaineers of Nepal, we named three of the previously unnamed fruit fly genes implicated in metabolic rewiring as Pasang Lhamu, Tenzing Norgay, and Phurba Tashi,” said Jha et al. (2015), a graduate student in Kevin White’s lab and the first author of the study. When the research team examined similar genes in highaltitude populations, they found several single mutation differences between high-altitude human populations and their lowland neighbors. Human comparative data from Andeans (n = 10), Sherpas (69) Tibetans (96), and Ethiopian highlanders (165) showed that of the 102 human genes that are similar to the 55 hypoxia genes in fruit fly, more than 40 appear to enable hypoxia tolerance in Sherpas, Tibetans, and Ethiopian highlanders. A smaller number (n = 21) of genes were shared in the Andean population, which may have been due to the small sample size (just ten individuals). Professor White explains, “These results show that, to our surprise, genetic variation in the same types of genes can produce hypoxia resistance in both humans and fruit flies. This result implies that even across hundreds of millions years of evolution, organisms can arrive at convergent solutions during adaptation to similar types of environmental change. ” Armed with the new data, the team will pursue teasing out the individual contributions and functions of the candidate genes they have identified.
Système de vision hybride : modélisation et application au suivi haute résolution

Cette these traite du suivi automatique de personne a travers la mise en oeuvre d'un systeme de vision hybride alliant un capteur ayant un grand champ de vue et une resolution faible avec un dispositif Pan-Tilt-Zoom orientable garantissant le detail de l'information. Une premiere partie est consacree a la proposition d'une solution originale de calibrage lorsque les centres optiques des deux capteurs sont pratiquement confondus. Dans une seconde partie, nous abordons la mise en relation des informations extraites de chaque capteur et leur enrichissement mutuel necessaire a la relation du suivi de personne basee sur une approche de filtrage particulaire : l'etape de prediction du filtre est guidee par la detection issue de la camera statique et la mesure est donnee par une modelisation d'apparence de la cible extraite de la camera dynamique. Enfin, les premiers resultats de suivi sont presentes et analyses
A Hydrosurgery System (Versajet) with and without Hydrogen Peroxide Solutions for the Debridement of Subacute and Chronic Wounds: A Comparative Study with Hydrodebridement

OBJECTIVE: The aim of this study was to evaluate the efficacy of hydrosurgery prepared with or without hydrogen peroxide for the management of subacute and chronic wounds. METHODS: This is a retrospective study on patients with infected subacute and chronic wounds. The wounds were debrided using hydrosurgery prepared with (the study group) or without hydrogen peroxide before grafting the wound (the control group). RESULTS: There were 60 patients in the study group and 70 patients in the control group. The hospital stay (mean, 7.83 [SD, 2.16] vs 9.86 [SD, 3.41] days; P < .001) and graft viability (mean, 3 [2–3] vs 2 [2–3]; P = .001) were significantly better in the study group than in the control group. The difference of hemoglobin levels after surgery was also significantly lower in the study group (0.1 [0–0.48] vs 0.45 [0–1]; P = .004). CONCLUSIONS: Encouraging results were obtained with the use of the hydrosurgery system prepared with hydrogen peroxide for infected subacute and chronic wounds. This method decreased hospital stay and bleeding, thus providing better contact of the skin graft with the wound bed, allowing early rehabilitation. The findings of the authors’ study need to be substantiated in large-scale randomized controlled trials.
Equity crowdfunding -A finnish case study

Crowdfunding grows at rapid pace internationally, and global platforms like Kickstarter and Indegogo are main leaders of this trend. Within the scope of this paper, we investigate the case of crowdfunding in Finland and identify particular national needs and potential what this new phenomenon has. The phenomenon of the Crowdfunding has been growing at a rapid pace in Finland, with it being seen as fundraising and effective marketing tool. Especially start-ups have started using the power of the crowd to promote their ideas and products as well as to raise funding. They are very opened to use Crowdfunding as an additional source of finance during their first round of financing. The effect of global platforms like Kickstarter and Indegogo, and in addition successful national ventures like Timo Vuorensola's campaigns for the new movie Iron Sky popularised Crowdfunding in Finland demonstrates the power of this instrument. In particular the younger audience is opened for this new tool. Within the scope of this paper we analyse the power of Crowdfunding in the Finnish context based on a literature study, and analysis of data gathered from Crowdfunding platforms.
Reusable software architectures for aerospace systems

Modern, complex control systems for specific application domains often display common system design architectures with similar subsystem functionality and interactions. The similarities between these subsystems in most spacecraft can be exploited to create a model‐driven system development environment and then transformed into software or hardware either manually or automatically. Modifications to software and hardware during operations can be similarly made in the same controlled way. The approach is illustrated using a spacecraft attitude determination and control subsystem, but applies equally to other types of aerospace systems.
Photogating of ionic currents across the lipid bilayer

The ionic currents of positive and negative hydrophobic ions across a approximately 7-nm-thick lipid bilayer are gated by photoformation of metalloporphyrin cations in the ester region of the bilayer by electron transfer to aqueous acceptors. At low concentrations of the hydrophobic ions there is a 30% change in the conductivity upon photocharging the membrane. The conductivity decreases with increasing concentration of tetraphenylphosphonium cations (TPhP/sup +/) and increases greatly with increasing concentration of tetraphenylboride anions (TPhB/sup -/). The observed photogating of hydrophobic ion currents is attributed to space charge effects in the bilayer. <<ETX>>
Co‐existence and elimination of convergent motor nerve terminals in reinnervated and paralysed adult rat skeletal muscle.

1. Experiments were carried out to determine whether neuromuscular synapse elimination can occur in skeletal muscle in the complete absence of conducted neural activity, using reinnervation of partially denervated adult muscle as a paradigm. Partially denervated rat lumbrical muscles were paralysed with a nerve conduction block applied to the sciatic nerve during regeneration of injured sural nerve motor axons. Both intact (lateral plantar nerve) and regenerating motor axons converging on the same muscle fibres were therefore inactive. 2. Paralysed muscles expressed prolonged twitch contractions, low tetanus‐to‐twitch ratios, prolonged synaptic potentials and marked post‐tetanic potentiation of frequency of miniature endplate potentials compared with control muscles and neuromuscular junctions. 3. Isometric tension and intracellular recording data suggest that regenerating axons reinnervated more muscle fibres in paralysed muscles than in controls. A greater proportion of muscle fibres was polyneuronally innervated in the paralysed muscles, but significant numbers of muscle fibres acquired a mononeuronal innervation by regenerated, inactive motor nerve terminals. 4. The data suggest that muscle paralysis enhances the regeneration of motor axons when they grow into partially denervated muscles, but activity‐independent competition may also be important in the mechanism of synapse elimination at neuromuscular junctions. The data further imply that when nerve endings expressing identical patterns of activity converge on a postsynaptic cell, Hebbian rules may not be sufficient to predict the outcome of the competition, contrary to specific postulates of the neurotrophic theory of development and maintenance of neural connections.
One big, and many small reasons that direct selection on offspring number is still open for discussion

In a recent paper, I proposed that natural selection should act to increase offspring number when diversification bet hedging is favoured. The simple underlying reasoning is that a target diversification strategy is more reliably generated with increasing sample size. The intention of opening a discussion has been realized; recent criticisms of the idea argue that selection does not act to increase offspring number when population size is large or infinite. Here I agree that criticisms have merit; indeed they are largely confined to the caveats discussed in my original paper. The critique, however, implies a verdict of outright rejection of the idea of selection on offspring number, which would be erroneous. Contrary to the assertions of the criticism, then, the importance of selection acting directly on offspring number remains an open question.
A new topology for power control of high efficiency class-E power amplifier

In this paper a new methodology to improve overall efficiency of class E power amplifier is proposed. Power amplifiers are designed to have the maximum efficiency at its highest output power but the efficiency decreases as the output power is reduced. To have more battery life and blocking interference, output power must be controlled due to the distance between the transmitter and the receiver. This new methodology uses optimized circuit topology in power control unit to have small drop in efficiency at low output power. Proposed circuit is simulated with Hspice in 0.25/spl mu/m CMOS technology and ADS lumped model of spiral inductors is used. The results show that the efficiency drop is about 40% when power amplifier is work with its 10% of output power.
An on-line BCI for control of hand grasp sequence and holding using adaptive probabilistic neural network

This paper presents a new EEG-based Brain-Computer Interface (BCI) for on-line controlling the sequence of hand grasping and holding in a virtual reality environment. The goal of this research is to develop an interaction technique that will allow the BCI to be effective in real-world scenarios for hand grasp control. Moreover, for consistency of man-machine interface, it is desirable the intended movement to be what the subject imagines. For this purpose, we developed an on-line BCI which was based on the classification of EEG associated with imagination of the movement of hand grasping and resting state. A classifier based on probabilistic neural network (PNN) was introduced for classifying the EEG. The PNN is a feedforward neural network that realizes the Bayes decision discriminant function by estimating probability density function using mixtures of Gaussian kernels. Two types of classification schemes were considered here for on-line hand control: adaptive and static. In contrast to static classification, the adaptive classifier was continuously updated on-line during recording. The experimental evaluation on six subjects on different days demonstrated that by using the static scheme, a classification accuracy as high as the rate obtained by the adaptive scheme can be achieved. At the best case, an average classification accuracy of 93.0% and 85.8% was obtained using adaptive and static scheme, respectively. The results obtained from more than 1500 trials on six subjects showed that interactive virtual reality environment can be used as an effective tool for subject training in BCI.
Méthodes à haute résolution pour antennes non uniformes

Dans cette these, nous nous interessons aux methodes de traitement d'antennes pour la localisation de sources dans le cas des antennes lineaires non uniformes. Le travail porte principalement sur les methodes a haute resolution qui sont particulierement adaptees aux antennes lineaires non uniformes afin de s'affranchir des problematiques associees aux lobes secondaires. Nous demontrons que Root-MUSIC peut etre directement appliquee dans le cas des antennes non uniformes lacunaires. De plus, nous montrons que la suppression d'un certain nombre de capteurs d'une antenne lineaire uniforme ne degrade que tres legerement les performances grâce a l'utilisation des methodes a haute resolution comme Root-MUSIC. Ensuite, nous proposons une nouvelle methode EM-ESPRIT qui peut etre utilisee pour n'importe quel type de geometrie d'antenne non uniforme. Cette methode iterative est basee sur les deux algorithmes : Expectation-Maximization (EM) et ESPRIT. L'etude des performances de EM-ESPRIT montre qu'elle presente de meilleures performances que la plupart des methodes, en particulier pour des niveaux de bruit importants. De plus, deux variantes : EM-ESPRIT stochastique et EMRoot- MUSIC sont proposees afin d'ameliorer les aspects de convergence et de consistance de EM-ESPRIT. Finalement, nous considerons une application liee a la localisation de sources aeroacoustiques sur la carrosserie d'une voiture. La mise en oeuvre d'une methode de type Zero-Forcing MUSIC a permis d'obtenir de bons resultats sur des donnees simulees et reelles, en particulier pour des sources proches et de puissance differente.
Extension of the Thomas-Fermi-Dirac-Weizsacker model: four-order gradient corrections to the kinetic energy

The authors present an accurate numerical solution of the variational equation resulting from the standard Thomas-Fermi-Dirac-Weizsacker energy functional plus four-order gradient terms of the kinetic energy. They show that the solution of the variational equation leads to kinetic energies that differ from estimates obtained by evaluation of the kinetic energy functional to fourth order with Hartree-Fock densities.
Automatic generation control of three-area small hydro system based on fuzzy PID control

The whole country has built a lot of small power plants with the development of micro-grid in recent years. The link between different areas becomes stronger since the development of grid technology. So AGC of linked systems is getting more important. Take linked systems among three small-hydro power plants for instance, a model of the linked system's AGC is built by MATLAB SIMULINK, then FPID algorithm is employed to control the system. By adjusting the controller, frequency deviation and tie-line power deviation of the system are controlled within the allowable range. Comparing the control results of FPID and PID algorithms, The simulation results show that in multi-area systems, under multiple constraints, fuzzy PID control algorithm is superior to conventional PID algorithm in the aspect of frequency stability and control speed. In the face of uncertainties caused by governors and turbines parameters change and loads disturbances, fuzzy PID algorithm can guarantee the control performance, and the result shows good robustness and dynamic performance. The proposed controller demonstrates good tracking and anti-jamming performance characteristics.
Modèles Multi-Agents pour l'Aide à la Décision et la Négociation en Aménagement du Territoire

Cette these porte sur l'utilisation de systemes multi-agents (SMA) pour l'aide a la decision et la negociation en amenagement du territoire, et a ete conduite en collaboration avec la societe CERREP SA. Dans une premiere partie, nous presentons les problemes de l'expertise, de la decision et de la negociation pour des projets d'infrastructures lineaires. Puis nous introduisons les SMA, avec une definition orientee vers la conception. Nous proposons diverses references sociologiques pour structurer l'analyse des systemes sociaux artificiels. Dans une deuxieme partie, nous abordons l'utilisation de SMA, pour la modelisation, la simulation et la resolution de problemes, mais aussi la dialectique entre SMA reactifs et cognitifs et l'apport de la sociologie. Nous presentons la bibliotheque SMARRPS dediee a la resolution de problemes spatialises. Et nous poursuivons avec trois modeles formels abordant le probleme de la convergence. Dans une troisieme partie, nous decrivons deux applications realisees : tout d'abord, le systeme SMAALA, pour l'aide a la localisation d'infrastructures. Ce systeme d'aide a l'expertise, calcule les ensembles de choix possibles (fuseaux) a partir de cartes de sensibilite environnementale de contraintes structurelles, et de descriptions des preferences des acteurs. Il s'appuie sur une architecture SMARRPS, proche des representations utilisees par les experts, ajustable dynamiquement, et autorisant la specification de contraintes heterogenes. Puis nous presentons SANPA, un systeme pour l'aide a la negociation de projets en amenagement , de facon distribuee et asynchrone (sur internet). Ce systeme s'appuie sur une communaute d'agents assistants, echangeant avec un agent gestionnaire de projets, et des structures de type SMAALA pour la representation spatiale. SANPA utilise des messages structures, fondes sur la theorie des actes de langage. Nous concluons en indiquant les perspectives d'integration de systemes d'information en environnement sur les bases multi-agents.
Empresas multinacionales de base tecnológica de origen venezolano: aplicación de teorías en casos de estudio

This article presents two cases of technology-based companies of Venezuelan origin, which in addition to becoming internationalized, became multinationals with a regional scope. The purpose of this descriptive work is to establish which of the explanatory theories of internationalization and multinationalization processes are applicable to the analyzed cases of study. The qualitative methodology was used based on the case study. The data were obtained from the application of an interview in one of the companies and secondary sources obtained from the other. The conclusion of the study is that all the theories that explain the multinationalization of companies are applicable to the cases studied, but only the International New Ventures Model can be related to the internationalization process followed by the organizations analyzed
Mitotic Responses to Injected Extracts of Larval and Adult Schistosoma mansoni in Biomphalaria glabrata: Effects of Dose and Colchicine Treatment

Biomphalaria glabrata snails injected with extracts of Schistosoma mansoni miracidia, mother sporocyst excretory–secretory product, cercariae, and adults, showed increased mitotic activity in histological sections of the amebocyte-producing organ (APO) relative to water-injected controls. The mitotic response was generally higher to extracts adjusted to 1.0 mg protein/ml than to a 10-fold lower concentration, although in most cases this increase was not statistically significant. Colchicine treatment prior to fixation significantly increased the number of mitotic figures in APOs of all groups of extract-injected snails, both with respect to water-injected controls and, with 1 exception, relative to matched colchicine-untreated snails. Extracts of adult worms elicited a pronounced mitotic response, suggesting that adults may share a mitogenic molecule with larvae. The high variability in counts of mitotic figures may limit the usefulness of this histological method.
Nuclei act as independent and integrated units of replication in a Xenopus cell‐free DNA replication system.

We have used a novel approach to investigate the control of initiation of replication of sperm nuclei in a Xenopus cell‐free extract. Nascent DNA was labelled with biotin by supplementing the extract with biotin‐11‐dUTP, and isolated nuclei were then probed with fluorescein‐conjugated streptavidin. Flow cytometry was used to measure the biotin content of individual nuclei and their total DNA content. This showed that incorporation of the biotinylated precursor increases linearly with DNA content. Haploid sperm nuclei replicate fully to reach the diploid DNA content over 2‐6 h in the extract. Synthesis stops once the diploid DNA content is reached. Different nuclei enter S phase at different times over greater than 1.5 h, although they share the same cytoplasmic environment. Nuclei reach their maximum rates of synthesis soon after entry into S phase and some replicate fully in less than 0.5 h, resembling the rates of replication observed in the intact egg. These results indicate that initiations are coordinated within each nucleus such that the nucleus is the fundamental unit of replication in the cell‐free system.
A study of prediction and outcome in a mental health crisis clinic.

Sixty-eight patients who came voluntarily to a crisis intervention clinic were randomly assigned to one of two groups. Those in the first group received immediate intervention therapy while those in the second were put on a waiting list. By the end of six weeks (and after minor changes in the makeup of the groups were taken into account) there was no significant difference in the psychiatric morbidity scores of the two groups; both had improved. The authors used a variety of pretreatment and posttreatment measures and found that the best predictor of a patient's condition at the end of six weeks was his pretreatment psychiatric morbidity score. The authors conclude that individuals vary in both their reactions to life crises and their therapeutic needs and that the central issue may not be the recovery itself, but the difficulty and pain with which it is achieved.
Broad overview of oxidative stress and its complications in human health

There is extensive literature dealing with toxicity and human health. A goodly portion puts focus on involvement of electron transfer, reactive oxygen species and oxidative stress involving body organs. There is evidence for prevention or amelioration by antioxidants. This is one mechanism which is part of a multifaceted mode of action. This review comprises an update of earlier literature.