Miracle-dz/UniFAR-FTUs huggingface dataset:
INNOVATION: A CASE STUDY OF AN ENGLISH TEACHERS’ INDUCTION

espanolLa induccion de profesores nuevos usualmente no es el foco de un programa de ingles como lengua extranjera. En muchas instituciones, la experiencia de los profesores con respecto a su orientacion recibe poca atencion, con el resultado de estres, relacionado con el trabajo, al comienzo de su contrato. En consecuencia, no solo la calidad de la ensenanza se ve afectada, sino tambien la motivacion del profesor y su percepcion de su lugar de trabajo. Este articulo de investigacion analiza los resultados de un estudio de caso de una innovacion a la induccion de profesores nuevos de un programa de lenguas en la ciudad de Cuenca, Ecuador. Para esto, el estudio de caso se baso en la comunicacion bidireccional entre la administracion y el personal docente por medio de retroalimentacion directa, la consideracion de principios administrativos de programas de lenguas, asi como la aplicacion de una encuesta a los profesores despues de la implementacion. Como resultado, la innovacion de la induccion de profesores nuevos parece haber reducido el estres laboral de los profesores durante la primera semana de clases; asi, ayudo a crear un ambiente de aprendizaje donde el programa, sus profesores y sus alumnos se benefician en general. EnglishThe induction of new English teachers is not often made the focus of language programs. In many institutions, the orientation experience receives little attention, resulting in work-related stress at the beginning of an instructor’s teaching contract. Consequently, not only the quality of teaching is affected but also the teachers’ motivation and perception of the program. This research article analyses the results of a case study of an innovation to a new teacher induction in a language program in the city of Cuenca, Ecuador. For this, the case study was based on two-way communication between the administration and the teaching staff through direct feedback, the consideration of language program management principles, as well as the application of a teacher survey after implementation. As a result, the innovation to the induction of new teachers seemed to reduce teachers’ job-related stress during the first week of classes, thus helping to create a learning environment where the program, its teachers, and its students benefit as a whole.
Acrometastasis as first sign of adenocarcinoma of the lung

Lung cancer effect 1.8 million people worldwide each year and cause around 1.6 million people dead [1]. In The United State of America lung cancer effect 230.000 people and cause death of more than 140.000 people each year [2]. The symptoms and evidence of lung cancer might be caused by the local and distance metastases or seconder to the paraneoplastic syndrome. The most common symptoms are cough, dyspnea, chest pain, and weight loss [3]. Cough is the main reason for pysician visit around 50% 75% of cases and mostly found in central airway squamous cell carcinoma and small cell lung cancer. Otherwise hemoptysis is present in 20% 50% of patients in their irst hospital visit [4,5]. Bone metastasis due to malignancies usually occur to the red marrow rich bones and rarely metastasis to the acral bones [6]. Almost half of the acral metastases that have reported in the literature are from lung cancer. Following lung cancers the most common acral metastasis are coming from kidney and breast cancers. Acral metastases are seen in the age range of 18-91 years, with a mean age of 58 years. Overall the most common location of metastases is the right hand and third inger [7-10].
Who benefits from radical innovations of SMEs? – Empirical evidence from the German Biotechnology

Radical innovations are of key importance from an economic point of view since they bear the potential to trigger the emergence of new technological trends and fuel economic prosperity while simultaneously causing far-reaching structural change processes. In this paper we focus on the transfer channels of radical innovations launched by small and medium-sized firms (SMEs). Based on a unique longitudinal dataset covering the observation period 1996 2016, we identify and trace back radical innovations of SMEs in the German Biotech in order to analyze the extent to which SMEs themselves or eventually also other organizations in their direct cooperation surrounding benefit from radical innovations in terms of subsequent innovation performance. Results from panel data count models indicate that direct cooperation partners of “radical innovators” generally seem to show higher innovative performance than partners of the control group, i.e. not radical innovating “statistical twin” firms. A more differentiated picture emerges if one considers the geographical and technological proximity of the cooperation partners.
Exploring Orthodox Christian Religious leader's attitude on Productive Roles of Women: The Case of Gondar City administration

This averts the traditional role of women hindered at the domestic level, like home maker and mother. From this one can understand that the increasing of women in employment has been dynamic and will shift the life of women. Thus equality of equal pay conditions will achieve. The triple role of women as productive, reproductive and community management role is common in most developing countries. Women productive roles are done with other chores responsibilities like child bearing and community roles.
STOOL ANTIGEN (HPSA) TEST IN DETECTION OF HELICOBACTER PYLORI INFECTION AMONG ADULT DYSPEPTIC PATIENTS IN TRIPOLI, LIBYA

Background. Helicobacter pylori is the most common infection in the world. Relationship between H. pylori and dyspepsia was confirmed by many studies, it has been strongly associated with peptic ulcer disease and gastric cancer. In that respect, several invasive and noninvasive methods for the diagnosis of H. pylori infection were utilized. Objective. The aim of the study was to evaluate the association between dyspepsia and the positivity of H. pylori stool antigen test, to compare this test with serological IgG test. Methods. 125 adult patients were randomly selected from gastroenterology units of Mediterranean and Tajurah clinics in Tripoli. Stool samples were taken for detection of H. pylori antigen by enzyme immunoassay. Blood samples for detection of anti-H. pylori IgG antibodies were taken. Data were statistically analyzed using SPSS. Results. 125 dyspeptic patients: 47 male and 78 female, aged 18-83 years old were examined. 80 patients were infected by H. pylori that was proved by a positive stool test, 88 had a positive IgG test. The prevalence was higher in the patients aged 28-47 years old. There was substantial relation to age, marital status and economic risk factors; there was no association between H. pylori and gender, sources of drinking water, living standards, smoking, family history of peptic ulcer, drug consumption, and blood groups. Conclusions. Relatively high rates of detection by HpSA prove that stool testing might be a reliable, simple, inexpensive, and non-invasive alternative test ащк detectшщт of H. pylori, diagnosing active infection and confirming cure. However IgG test has a low sensitivity, specificity, and accuracy compare to the HpSA test. Thus it can be used for screening purposes.
Synthesis of elements for conducting a randomization test

Randomization tests offer an access to inference statistics, which is regarded as particularly simple in the didactic literature. Above all, the logic of the inferential reasoning should become particularly clear. Nevertheless, in order to carry out a randomization test, some elements are needed that must be understood in order to successfully draw statistical conclusions. In this article, various elements from the literature are collected and compiled in order to create a scheme for the hand of learners to carry out a randomization test.
Depression, Anxiety and Stress: A comparative study of Internet addicts and non addicts.

Internet technology is growing rapidly in today’s era. It investigated also effect on human mental health. In this study the differences between internet addicts and non-addicts on depression, anxiety and stress. Total number of 200 sample of was collected. Among the sample, 64 subjects (32%) was identified as high internet addicts and 68 subjects (34%) were identified as noninternet addicts. In this study, the Internet Addiction Test and Depression Anxiety and Stress Scale were used. The data was collected and analyzed using mean and standard deviation for research question while ttest was used for test of hypothesis. The result indicates that there was a significant difference in depression, anxiety and stress among internet addicts and non -addicts. In another word we can say that internet addicts were more Depression, anxious and Stressed than non -addicts. Studies have shown that problems related to Depression, Anxiety and Stress is seen more in those who are internet addicts.
University of Southern Denmark Increased Pain Sensitivity in Accident-related Chronic Pain Patients with Comorbid Posttraumatic Stress Vaegter,

Objectives: Posttraumatic stress disorder (PTSD) is prevalent in chronic pain, and associated with increased pain, hyperalgesia and psychological distress. This study aimed to investigate antinociceptive and pro-nociceptive pain mechanisms, pain intensity, and psychological distress (depression, anxiety, pain catastrophizing, and fear of movement) in patients with accident-related chronic spinal pain with (N=44) and without (N=64) comorbid PTSD characteristics. Methods: Cuff algometry was performed on lower legs to assess pressure pain threshold (cPPT), tolerance (cPTT), temporal summation of pain (TSP: increase in pain scores to ten repeated stimulations), and conditioning pain modulation (CPM: increase in cPPT during cuff pain conditioning on the contralateral leg). Warmth detection threshold (WDT) and heat pain threshold (HPT) at the hand were also assessed. Clinical pain intensity (numerical rating scale), psychological distress, and PTSD symptomatology (ICD-11) were assessed with questionnaires. Mediation analyses were performed to investigate possible psychological mediators in the associations between PTSD and pain (intensity and mechanisms). Results: Patients with PTSD demonstrated increased pain intensity, and psychological distress as well as reduced WDT and cPTT compared with patients without PTSD (P < 0.05). No significant differences in cPPT, HPT, TSP and CPM were found. The association between PTSD and pain intensity was mediated by pain catastrophizing, and fear of movement mediated the association with
CTLA-4 and PD-L1/PD-1 Pathways: Immune Checkpoint Inhibitors and Cancer Immunotherapy

The immune system developed certain checks and balance to control or inhibit the reactivity against normal cells of the body. Uncontrolled immune responses to the non-self entities such as bacteria, viruses, parasites, or mutated self-antigens can cause an inflammatory reaction and autoimmune diseases. To avoid an immune overreaction, the immune response is governed by a delicate balance between the expression of co-stimulatory and inhibitory signals. These signals of the immune system referred to as immune checkpoints that are crucial to maintaining the homeostasis in the body. T-cells are an important subtype of lymphocyte that plays a key role in the fighting against several diseases including cancer. Accumulation of CD8+ T cells in the tumor microenvironment (TME) directly correlates with the favorable anti-tumor responses [1]. Activated T cells express several coinhibitory receptors including programmed cell death protein 1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4). The interaction between PD-1 and its ligand PD-L1 and, CTLA4 and receptor B7 regulate T cell responses to self-proteins [2]. Expression of ligands for the checkpoint is one of the prominent mechanisms exploited by cancer cells to avoid the immune cellmediated killing which helps in their unchecked growth and progression [3]. PD-L1 expressed by tumor cells to inhibit the function and activity of T cells, whereas B7 that pairs with CTLA4 is expressed by antigen-presenting cells (APCs). Immunosuppressive TME which consists complex network of cancer cells, tumor-manipulated stromal and immune cells and soluble factors affects the functions of CD8+ T cells by inhibiting their activity or inducing apoptosis [4]. To keep the CD8+ T cells active in TME and perform their anti-tumor function, several CTLA-4 and PD-1/PD-L1 signaling axis blocking agents were developed as new immunotherapeutic tools which demonstrated huge therapeutic potential across multiple histological tumor subtypes [4,5].
A Study on the Effectiveness of Teaching the High Achievers in English through Task-Based Method (TBLT) and Bilingual Method at Secondary Level in the Birbhum District

DOI: 10.21276/sjahss.2017. 5.12. 3 Abstract: Second Language Teaching in classroom situation is still a process of research and experimentation since no methodological paradigm has proved to be efficacious in ensuring total skill development among the L2 learners. Nevertheless a persistent attempt is being seen among both the policy makers and the practicing teachers of second language to try out the commonly accepted theoretical paradigms in the L2 classroom situations. Thus oftentimes it becomes a challenging task for the second language teacher. The teacher has to make hectic effort to generate the four fundamental language skills among the learners in a heterogeneous classroom situation. Generally, in the Indian situation the L2 teachers are inclined to practice the Bilingual Method to generate competencies among the learners. But the heterogeneous levels of learners due to varied degree of capability cannot be equalized in terms of skill development through this method that makes use of mother tongue equivalent and translation device in teaching English in the classroom situations. On the contrary, if teaching situation is controlled through Task-Based method which is activity oriented and learner-centric, second language learning may be a joyful experience so that the learners get motivated to be associated in the language process. The present Study is an attempt to explore experimentally the comparative effectiveness of the Bilingual Method of teaching and teaching with Task-Based method in the second language classroom situation.
A Systematic plan of Blockchain Technology on Security Key

In recent decades, blockchain has (slowly) become one of the most frequently discussed methods for securing data storage and transfer through decentralized, trustless, peer-topeer systems. This review provides a complete and detailed documentation of the present technological and literary state of the Blockchain technology within Information Systems research. This paper also identifies peer-reviewed literature that seeks to apply blockchain for cyber security purposes and presents a systematic analysis of the most commonly approved blockchain security applications. It reviews moreover categories the current findings into different concept categories to enable further research into the area. Finally, it is noted that the Blockchain technology in its present state still has way to go before the technology will reach a state considered sufficient for mainstream adoption.
International Market Selection Model Using Newly Developed Geometric International Market Selection Space

International Market Selection (IMS) is literally a process in identifying and selecting feasible international market opportunities for exporting. It is a methodological process whereby suitable variables are vetted through a model in order to produce output in the form of processed information that would help export marketers in decision-making. The new IMS model, introduced as Geometric International Market Selection Space (GIMSS), rooted from the Trade Intensity Index (TI) Index and Geometric Trade Intensity Space Box (GTISB) is proposed as a complimentary tool to be used by international marketers. The constructed GIMSS model utilises both trade elements (exports and imports) with no filtering and weighting processes, employs changes within changes measurement, embeds quality perspective measurement as alternative game changer in identifying International Export Opportunities (IEO), and able to do future projection of IEO. In addition, even though this GIMSS model does not have weighting scheme, it can still perform trade-off process between volume and quality elements. The GIMSS is capable of identifying and categorising the host country market potential into low, intermediate or high market potential at product level. With that policy maker would be able to employ this information conjointly with competitive index of exporting country and make assessment in the perspective of cross checking between host country market potential levels with exporting country competitive advantage status.
Adipocytokines, Insulin Sensitivity and Endothelial Dysfunction among offsprings of Type 2 Diabetes Mellitus

Prevention of diabetes and its associated burden has become a major health issue worldwide. The present study was undertaken to assess the changes in insulin sensitivity and endothelial dysfunction well before the onset of diabetes in population with positive family history for diabetes. The objectives of the study is to estimate the levels of serum Adiponectin, Visfatin, Insulin, HOMA IR and platelet derived microparticles P-selectin levels in offspring of type 2 Diabetes mellitus. The healthy volunteers who are aged between 1822 years of either sex, were selected based on their family history of diabetes. The study showed a significant decrease in serum Adiponectin and increase in serum Visfatin, Insulin, HOMA IR & P-selectin levels in the offspring of type 2diabetes. The Adiponectin showed a negative correlation with Visfatin, P selectin, Insulin & HOMA IR. Genetic predisposition for diabetes may influence adipocytokine levels which might play a key role in developing diabetes in near future.
Wartość diagnostyczna czynnego testu pochyleniowego z zastosowaniem nitrogliceryny

Wstep: Omdlenia wazowagalne (VVS) stanowią okolo 30% wszystkich omdlen. Uznaną metodą w diagnostyce tych utrat przytomności jest test pochyleniowy (HUTT), ktorego czulośc waha sie od 32% do 74%. Aby ją zwiekszyc, stosuje sie prowokacje farmakologiczną. Do najcześciej stosowanych lekow nalezą izoprenalina i nitrogliceryna. Material i metody: Badaniem objeto 157 chorych (99 kobiet i 58 mezczyzn w wieku 13-70 lat) z omdleniami o nieustalonej etiologii oraz 15 zdrowych ochotnikow. Pionizacje pacjenta poprzedzal 30-minutowy okres odpoczynku, po ktorym nastepowala pionizacja do kąta 60°. Test bierny (bez obciązenia farmakologicznego) trwal 60 min (40 pts.) lub 45 min (117 pts.). W wypadku braku przedomdlenia lub omdlenia podawano podjezykowo 0,25 mg nitrogliceryny i kontynuowano badanie przez kolejnych 20 min. Typ omdlenia rozpoznawano na podstawie klasyfikacji VASIS z 1992 roku (z uwzglednieniem poprawek VASIS z 1999 roku). Wyniki: Na podstawie wynikow grupy badanej i kontrolnej oceniono czulośc i swoistośc HUTT z zastosowaniem nitrogliceryny na 59% i 87%. Odpowiedź falszywie dodatnia po nitroglicerynie wystąpila w 8 (5%) przypadkach w grupie badanej i u 1 (7%) chorego z grupy kontrolnej. Ciśnienie tetnicze Wnioski: Zastosowanie nitrogliceryny podanej podjezykowo w czasie HUTT pozwala zwiekszyc czulośc badania, przy umiarkowanym zmniejszeniu jego swoistości. W czasie kwalifikacji pacjentow do czynnego testu z uzyciem nitrogliceryny nalezy zachowac szczegolną ostroznośc.
Dynamic Immune Activation: Upregulation of Immune Inhibitory Pathways in Gastric Cancer

In the tumor microenvironment (TME), aberrant inducement of coinhibitory molecules (including programmed cell death 1(PD-1), cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), lymphocyteactivation gene 3 (LAG-3), etc.) is a critical factor contributing to immune escape by the tumor. Effector immune cells with phenotype that upregulates these markers are associated with functional exhaustion, conferring upon tumor the potential to avoid immune control. However, these key molecules have been exploited as advantageous weapon in tumor immunotherapy, gradually reshaping recent cancer therapy mode. Until recently, the total remission rate of PD-1/programmed cell death 1 ligand 1 (PD-L1) blockade therapy in most tumors has been reported from about 20 to 30 percent [1,2]. For those patients who do not respond, the priority is to maximize the treatment effect through combinatorial therapy. As such, understanding of biological function of multiple immune checkpoints and their underlying molecular mechanism is of great value for exploring novel immune targets and combinatorial therapy mode.
Relationship between Students’ Perception of Quality of Instructional resources Used in Teacher Education Programmes and their Attitude towards Active Participation in Learning Activities in the Universities in Nakuru County, Kenya

DOI: 10.21276/sjahss.2018. 6.1. 29 Abstract: The objective of this study was to determine the relationship between students’ perception of quality of instructional resources used in teacher education programmes and their attitude towards active participation in learning activities in the universities in Nakuru County, Kenya.The study focused on quality of the Instructional resources namely: Time, Library, and Accommodation and Lecture Hall resources. Learning activities studied were Attending Lectures, Doing Assignments, Doing Private Studies, Sitting Exams and Participating in Group Discussions. Deming Fleming and Cognitive Dissonance Theory premised this study on the Theory of Total Quality Management for Attitude Change advanced by Festinger Leon. This research study adopted the descriptive survey research design.Data was collected from a sample population of 310 obtained from a total of 6 universitiesPrivate and Public Chartered Universitiesoffering teacher education programs. Stratified, purposive and simple random sampling techniqueswere used. Sample size was 257. Data from students’ questionnaires were analyzed using statistical tools in the Statistical Package for Social Sciences (SPSS). Descriptive statistics such as frequencies, percentages, means and standard deviations were calculated. Oneway Analysis of Variance, Post Hoc Test, T-tests were carried out to measure significant differences between means of samples. Pearson chisquarewas used to measure the association between dependent and independent variables. The study found out that students enrolled in teacher education programmes in private universities tend to perceive quality of instructional resources to be high compared to their counterparts in public universities.The Pearson Chi-Square test results in indicate that the association between students’ perception of quality of resources and attitudes was statistically significant at the . 05 level, χ2 (4, N = 229) = 196.268 p < 0.05. This study also found out that students enrolled in teacher education programs developed more positive attitude towards participation in learning activities whenever they perceived quality of instructional resources to be high.
Creating an Artiﬁcial Bokeh Blur

This work focused on how bokeh can be created and applied to images artiﬁcially. It utilized advancements made in machine learning, depth estimation techniques, and work in computational photography. Here we explore two techniques namely, Random forest based depth estimation and Disparity map generation form Stereo images to get depth/disparity maps and apply a defocus algorithm resulting in an artiﬁcial bokeh blur.