Miracle-dz/UniFAR-FTUs huggingface dataset:
Recovery characteristics using isoflurane or propofol for maintenance of anaesthesia: a double‐blind controlled trial

We studied 114 female patients (ASA 1 or 2) who were within 20% of ideal body weight and who were scheduled to undergo gynaecological laparoscopy which required supplementation with an opiold (groups I A and PA), or dental procedures which did not require opioid supplementation (groups IO and PO). A computerised package of psychomotor tests was performed before surgery. Anaesthesia was induced with propofol 2.5 mg.kg−1 and all patients received atracurium 0.3 mg.kg−1 and 67% nitrous oxide in oxygen. Patients in group I A received isoflurane 1% (inspired), and alfentanil 10 μg. kg−1 as a bolus and 10 μg. kg−1.h−1 as an infusion. Patients in group PA received propofol 9 mg.kg−1.h−1 as an infusion, decreasing to 6 mg.kg−1.h−1 after 15 min, together with alfentanil 10 μg. kg−1.h−1. Patients in groups IO and PO received isoflurane and propofol in the regimens described for groups 1A and PA, but without alfentanil. Recovery was assessed by a blinded observer who recorded times to awakening (eye opening) and orientation (giving date of birth), and who repeated the psychomotor tests at 1,3 and 5 h. Linear analogue scales of mood, nausea and pain were obtained and other side effects were noted in the succeeding 48 h. A matched control group of 25 females (who were not anaesthetised) underwent psychomotor testing on four occasions in order to assess the ‘learning effect’ of repeated recovery testing. The analysis of recovery tests did not assume a normal distribution. There were no significant differences in awakening or orientation times among the groups (median values IO: 4.92 and 6.06 min; PO: 3.88 and 5.11 min; IA: 6.90 and 7.98 min; PA: 6.24 and 7.30 min). There were also no differences among groups in respect of the results of psychomotor testing during recovery. There was significantly less nausea in group PO (6132 patients) than in group IO (13/32 patients). There was also a significant difference between the performance of the control group compared with those of the study groups in most of the tests, and this emphasises the importance of including a control group in studies which involve recovery testing. We conclude that, after induction of anaesthesia with propofol in unpremedicated outpatients, maintenance of anaesthesia with nitrous oxide and either isoflurane or propofol, with or without alfentanil, provides reasonably rapid and reliable recovery and are equally acceptable to the patient.
Pedicle Subtraction Osteotomy in the Cervical Spine

Study Design. Description of surgical technique with review of literature. Objective. To describe the surgical management of cervical spine deformity, using pedicle subtraction osteotomy. Summary of Background Data. Previous articles have primarily described Smith-Petersen osteotomies and Simmons' modifications to correct fixed cervical deformity. Those were typically performed with the patient awake and sedated in a seated position and without the use of spinal instrumentation. Methods. Description of a single surgeon's technique for performing pedicle subtraction osteotomy to treat fixed cervical deformity. Conclusion. The use of pedicle subtraction osteotomy in the cervical spine is a safe and effective procedure when performed by experienced surgeons and can result in a satisfying outcome for both the patient and the surgeon.
Exploring the Relationship between Employer Branding and Employee Retention

The work condition, these days, is winding up noticeably progressively focused. In such focused condition, boss marking is quick developing as a long haul human asset (HR) system to pull in and hold skilled workforce. The reason for this article is to decide the precursors of boss marking from the viewpoint of current representatives. Most reviews are committed to the examination of manager marking as an ability fascination method among potential representatives. Be that as it may, the exhibit explore inspects the effect of business marking on maintenance of existing workforce. The examine builds up a calculated structure of precursors and results of manager marking. Utilizing subjective information from a pilot investigation of an IT monster, it gives bits of knowledge in the matter of how the anticipated results of boss marking can prompt expanded maintenance among workers. The examination additionally breaks down the part of boss marking in building brand advocates who spread positive informal exchange about the association. Consequences of the subjective meetings demonstrate positive connection between results of business marking (work fulfilment and mental contract) and representative maintenance. Moreover, a positive relationship is found between manager marking and hierarchical duty which thusly contributes towards advancement of brand backing. Scholarly and administrative ramifications are likewise talked about. The review highlights the significance of manager marking build and its potential to mitigate the up and coming issue of representative weakening.
Effects of Insulin-Like Growth Factor-1/Binding Protein-3 Complex on Muscle Atrophy in Rats

Muscle atrophy and wasting is a serious problem that occurs in patients with prolonged debilitating illness, burn injury, spinal injury, as well as with space flight. Current treatment for such atrophy, which often relies on nutritional supplementation and physical therapy, is of limited value in preventing the muscle wasting that occurs. Considerable recent attention has focused on the use of anabolic growth factors such as insulin-like growth factor (IGF-1) in preventing muscle atrophy during limb disuse or with various catabolic conditions. However, potential side effects such as hypoglycemia appear to be limiting factors in the usefulness of IGF-1 for clinical treatment of muscle wasting conditions. The formulation of IGF-1 used in this study (IGF-1/BP3) is already bound to its endogenous-binding protein (BP3) and, as a result, has a greater specificity of action and significantly less hypoglycemic effect. Using a rat model of hind limb suspension (HLS) for 10 days, we induced marked muscle atrophy that was accompanied by enhanced muscle proteolysis and reduced muscle protein content. When HLS rats were treated with IGF-1/BP3 (50 mg/kg, b.i.d.), they retained greater body and muscle mass. Muscle protein degradation was significantly reduced and muscle protein content was preserved. The rate of protein synthesis, although somewhat reduced in HLS muscle, was not significantly elevated by IGF-1/BP3 treatment. Volume density of HLS-treated muscles were increased compared to untreated HLS rats and the actual number of fibers per area of muscle was likewise increased. The results of the current study suggest that IGF-1/BP3 might be useful for inhibiting muscle proteolysis in catabolic conditions and thus preserving muscle protein content and mass.
ASSOCIATION BETWEEN DAILY SITTING TIME AND PREVALENT METABOLIC SYNDROME IN AN ADULT WORKING POPULATION: THE AWHS COHORT.

OBJECTIVE the aim of this analysis was to measure the association between daily sitting time and prevalent metabolic syndrome, independently of the physical activity performed. SUBJECTS AND METHODS the Aragon Workers' Health Study cohort consists of 5 865 participants from which a sample of 1 415 male participants (40-55 years old) with completed data at baseline was selected. Sitting time and physical activity were assessed by validated questionnaires, and the socio-demographic, clinical and biochemical covariates needed to diagnose metabolic syndrome were collected as part of the study protocols. Metabolic syndrome was defined according to the modified National Cholesterol Education Program - Adult Treatment Panel III. Multiple linear and logistic regression models were carried out to quantify this association using sitting time categorized into tertiles. RESULTS mean sitting time was 5.78 ± 1.72 h/day, and the prevalence of metabolic syndrome was 19.2%. Comparing participants in the highest (> 6.57 h/day) versus lowest (1.85-4.57 h/day) tertile of sitting time, a positive association was observed for metabolic syndrome (OR 1.77, 95%CI: 1.25-2.49) and triglyceride (OR 1.70, 95%CI: 1.30-2.24), HDL-cholesterol (OR 1.65, 95%CI: 1.06-2.58), waist circumference (OR 1.57, 95%CI: 1.17-2.11) and fasting blood glucose (OR 1.35, 95%CI: 1.03-1.77) criteria, adjusting the level of physical activity. CONCLUSIONS higher sitting time is associated with an increased prevalence of metabolic syndrome independently of physical activity performed. These results could be useful to carry out effective strategies for cardiovascular health promotion especially in workplaces.
Assessing 3GPP Long Term Evolution (LTE)-Advanced as IMT-Advanced technology: the WINNER+ Evaluation Group approach

This article is describing the WINNER+ approach to performance evaluation of 3GPP LTE-Advanced proposal as IMT-Advanced technology candidate. Official registered WINNER+ Independent Evaluation Group evaluated this proposal against ITU-R requirements. First part of the article gives an overview on ITU-R evaluation process, criteria and scenarios. Second part is focused on the working method of the evaluation group emphasising simulator calibration approach. Finally the article contains exemplary evaluation results based on analytical and simulation approaches. The obtained results allow WINNER+ to confirm that the 3GPP LTE Release 10 & Beyond (LTE-Advanced) proposal satisfies all the IMT-Advanced requirements, thus it qualifies as IMT-advanced system.
Vaccine safety: injecting a dose of common sense.

Nonetheless, despite these public health triumphs, vaccines can and do occasionally cause harm. For example, the widespread use of the polio vaccine resulted in vaccine-associated paralytic polio in 1 of every 2.4 million vaccine recipients. For this reason, calls for alternate schedules and cessation of the use of this vaccine began in the mid-1980s. 7 Indeed, the Advisory Committee on Immunization Practices recently recommended that, by January 2000, US children should routinely receive only inactivated polio vaccine for all childhood doses. 8 Vaccines usually result in widespread and dramatic good but also occasional harm. Logically and rationally discerning cause and effect vs speculation or mere temporal associations in regard to vaccine adverse effects allows for wisdom on the part of patient and clinician in deciding whether to receive or promote a given vaccine. 9 As an example of discerning cause and effect, fear of Guillian-Barré syndrome (GBS) due to influenza vaccine is still prevalent. The 1976-1977 influenza vaccine was associated with a statistically increased risk of GBS in some, but not all, groups of recipients. 10 The biologic mechanism for this association has never been determined. During the 1992-1993 and 1993-1994 flu seasons, an excess risk of GBS of approximately 1 in 1 million doses delivered was found only when both seasons were combined for analysis. 11 Whether these statistical associations represent cause and effect remains unclear. Nonetheless, undue fear of such adverse effects prevents some older people who are at high risk of influenza-related hospitalization or death from receiving the vaccine (or some clinicians from recommending vaccination) simply because they fear GBS. Yet, by not accepting the vaccine, such individuals accept risks that are orders of magnitude higher (such as the 20,000 excess deaths or 250,000 excess hospitalizations due to influenza observed nearly every year) than any possible risk from the vaccine. Unfortunately health care workers themselves are not immune to unfounded fears of adverse effects. Despite being at moderate risk for hepatitis B infection and its chronic sequelae, health care workers were among the last to embrace receipt of the plasma-derived vaccine, due to unfounded concerns of possible human immunodeficiency virus contamination. 12,13 Finally, concern arose over the temporal association of varicella vaccination and occurrence of a rash in the first 2 weeks after its administration. Had the vaccine caused the very illness it was supposed to prevent? Polymerase chain reaction testing proved these concerns were unfounded by …
Convergence analysis of parameter estimation in system identification

For linear time-invariant system model, this paper analyzes the convergence of parameter estimations as the length of the input-output data tends to infinity through prediction error method. It is known that the sequence of the prediction errors, called criterion functions, converges uniformly in the parameter with probability one as the data length tends to infinity. Given an input-output data of fixed length, the parameter estimation is represented by a set in general, instead of by a single point, on which the criterion function takes its minimum. Thus a mathematical feature of the convergence problem of parameter estimation is in that we are needed, from the convergence of a sequence of functions, to infer the convergence of the sequence of their sets of minimizing arguments. The Hausdorff metric, as a rational due tool, is suggested to measure the distance between sets and then is used to discuss the convergence problem here. We show that, according to Hausdorff metric, the convergence of parameter estimation can not be guaranteed in general, and give some conditions to guarantee.
Delay-dependent exponential stability of stochastic delay differential system whose coefficients obey the polynomial growth condition

This article discusses the exponential stability of nonlinear stochastic delay differential systems (SDDSs) whose coefficients obey the polynomial growth condition. Delay-dependent criteria on almost sure exponential stability and pth moment exponential stability of such SDDSs have been established. By applying some novel techniques, our criteria work for many SDDSs including some cases in which the ℒV operator has a complicated form, which seemingly prevents the existing results from being directly used. The range of order of moment exponential stability and the decay rate can be estimated through the coefficients of the system.
Humoral and cellular immunity to hepatitis B virus-derived antigens: comparative activity of Freund complete adjuvant alum, and liposomes

Complete Freud adjuvant, aluminum gel, and liposomes were compared for their ability to enhance the immunogenicity of an intact 22-nm HBsAg particle vaccine and an HBsAg-derived polypeptide vaccine in guinea pigs. Both humoral and cell-mediated immune responses were evaluated. The greatest immune response was obtained with complete Freund adjuvant, regardless of the antigen preparation. Aluminum gel appeared to be a better adjuvant for 22-nm HBsAg particles, but the liposomes rendered polypeptide preparations more immunogenic. The possibility that various proportions were entrapped in aqueous compartments instead of being inserted into the lipid bilayers of liposomes might account for this difference. The development of both humoral and cellular immunity was dependent upon the use of an adjuvant, because aqueous preparations had poor immunogenicity.
Quantum Leap Pattern Matching

Quantum leap matching is introduced as a generic pattern matching strategy for the single keyword exact pattern matching problem, that can be used on top of existing Boyer-Moore-style string matching algorithms. The cost of the technique is minimal: an additional shift table (of one dimension, for shifts in the opposite direction to the parent algorithm’s shifts), and the replacement of a simple table lookup assignment statement in the original algorithm with a similar conditional assignment. Together with each of the conventional shift table lookups, the additional shift table is typically also indexed on the text character that is at a distance of z away from the current sliding window. Under conditions that are identified, the returned values from the two shift tables allow a “quantum leap” of distance more than the length of the keyword for the next matching attempt. If the conditions are not met, then there is a fall back is to the traditional shift. Quick Search (by Sunday) is used as a case study to illustrate the technique. The performance of the derived “Quantum Leap Quick Search” algorithm is compared against Quick Search. When searching for shorter patterns over natural language and genomic texts, the technique improves on Quick Search’s time for most values of z. Improvements are also sometimes seen for various values of z on larger patterns. Most interestingly, under best case conditions it performs, on average, at about three times faster than Quick Search.
Student Satisfaction with Quality of Accounting and Auditing Education: The Case of Vietnam

This research is conducted to examine and evaluate determinants influencing the level of student satisfaction in the quality of auditing and accounting training at Vietnamese universities. Data were collected from 213 students of accounting and auditing field in three universities of National Economics University, University of Commerce and Academy of Finance. Exploratory factor analysis (EFA) and linear regression models were employed to determine the determinants influencing student satisfaction about quality of accounting and auditing. The findings show that the strongest impact on student satisfaction was the ability to serve; then training program; infrastructure component, and the last of teaching team. Based on the results, some recommendations are proposed for improving the satisfaction levels of students of accounting and auditing. Keywords : Quality of service; Quality of training; Satisfaction
The S-Cube Knowledge Model - Experiences in Integrating SSME Research Communities

The field of Service Science, Management & Engineering (SSME), covers a wide range of research topics and has become fragmented due to the necessary specialization such broad area requires. The European Commission’s Network of Excellence in Software Services and Systems (S-Cube) is an attempt to bring scientists together to perform joint research in this field that crosses existing research boundaries and, in the process of doing so, to help establish an enduring European network of researchers practicing SSME. To assist in the consolidation of research and bridge the gaps between disciplines, the S-Cube Knowledge Model (KM) has been developed to provide a method of capturing, managing and refining the knowledge produced by the network and provide a common understanding of research outputs. This paper describes the motivation, requirements and realization of the S-Cube KM, which allows the collection, analysis and management of research within S-Cube and enables the extraction and combination of the explicit, cross-cutting knowledge embedded in collaborative research.
Modelling Recurrent Events for Improving Online Change Detection

The task of online change point detection in sensor data streams is often complicated due to presence of noise that can be mistaken for real changes and therefore affecting performance of change detectors. Most of the existing change detection methods assume that changes are independent from each other and occur at random in time. In this paper we study how performance of detectors can be improved in case of recurrent changes. We analytically demonstrate under which conditions and for how long recurrence information is useful for improving the detection accuracy. We propose a simple computationally efficient message passing procedure for calculating a predictive probability distribution of change occurrence in the future. We demonstrate two straightforward ways to apply the proposed procedure to existing change detection algorithms. Our experimental analysis illustrates the effectiveness of these approaches in improving the performance of a baseline online change detector by incorporating recurrence information. Read More: http://epubs.siam. org/doi/10.1137/1.9781611974348. 62
The composite resin restoration: a literature review. Part I. Proper cavity preparation and placement techniques.

Interest in nonalloy restorations have increased the usage of composite resins for Class II posterior lesions. Modifications of G.V. Black's original cavity design are discussed, to familiarize the practitioner with successful techniques that have increased the longevity of these restorations. The usage of bonding agents, and placement of the filled resin materials are also described.
Automated Integrative Complexity

Integrative complexity is a conceptually unique and very popular measurement of the complexity of human thought. We believe, however, that it is currently being underutilized because it takes quite a bit of time to score. More time-efficient computer-based measurements of complexity that are currently available are correlated with integrative complexity at fairly low levels. To help fill in this gap, we developed a novel automated integrative complexity system designed specifically from the integrative complexity theoretical framework. This new automated IC system achieved an alpha of . 72 on the standard integrative complexity coding test. In addition, across nine datasets covering over 1,300 paragraphs, this new automated system consistently showed modest relationships with human-scored integrative complexity (average alpha = .62; average r = .46). Further analyses revealed that this relationship consistently remained significant when controlling for superficial markers of complexity and that the new system accounted for both the differentiation and integration components of integrative complexity. Although the overlap between the automated and human-scored systems is only modest (and thus suggests the continued usefulness of human scoring), it nonetheless provides the best automated integrative complexity measurement to date.
Characterization of a Novel Human Herpesvirus 8-Encoded Protein, vIRF-3, That Shows Homology to Viral and Cellular Interferon Regulatory Factors

ABSTRACT The genome of the human herpesvirus 8 (HHV-8) contains a cluster of open reading frames (ORFs) encoding proteins with homology to the cellular transcription factors of the interferon regulatory factor (IRF) family. Two of these homologues, vIRF-1 and vIRF-2, were previously identified and functionally analyzed. In this study, we have characterized a novel gene, designated vIRF-3, encoded within the previously predicted ORF K10.5 and our newly identified ORF K10.6. Northern blotting of RNA extracted from BCBL-1 cells with a vIRF-3-specific probe and reverse transcription-PCR analyses revealed a single transcript of 2.2 kb with a splice present in the coding region. The vIRF-3 mRNA levels in BCBL-1 cells were increased upon 12-O-tetradecanoylphorbol-13-acetate treatment, with kinetics of expression similar to those of the early immediate genes. The vIRF-3 ORF encodes a 73-kDa protein with homology to cellular IRF-4 and HHV-8-encoded vIRF-2 and K11. In transient transfection assays with the IFNACAT reporter, vIRF-3 functioned as a dominant-negative mutant of both IRF-3 and IRF-7 and inhibited virus-mediated transcriptional activity of the IFNA promoter. Similarly, the overexpression of vIRF-3 in mouse L929 cells resulted in inhibition of virus-mediated synthesis of biologically active interferons. These results suggest that by targeting IRF-3 and IRF-7, which play a critical role in the activation of alpha/beta interferon (IFN) genes, HHV-8 has evolved a mechanism by which it directly subverts the functions of IRFs and down-regulates the induction of the IFN genes that are important components of the innate immunity.