Miracle-dz/UniFAR-FTUs huggingface dataset:
Q3-D3-LSA

QuantNet is an integrated web-based environment consisting of different types of statistics-related documents and program codes. Its goal is creating reproducibility and offering a platform for sharing validated knowledge native to the social web. To increase the information retrieval (IR) efficiency there is a need for incorporating semantic information. Three text mining models will be examined: vector space model (VSM), generalized VSM (GVSM) and latent semantic analysis (LSA). The LSA has been successfully used for IR purposes as a technique for capturing semantic relations between terms and inserting them into the similarity measure between documents. Our results show that different model configurations allow adapted similarity-based document clustering and knowledge discovery. In particular, different LSA configurations together with hierarchical clustering reveal good results under M3 evaluation. QuantNet and the corresponding Data-Driven Documents (D3) based visualization can be found and applied under quantlet. The driving technology behind it is Q3-D3-LSA, which is the combination of “GitHub API based QuantNet Mining infrastructure in R”, LSA and D3 implementation.
Performance Analysis and Modeling of Task-Based Runtimes

The shift toward multicore processors has transformed the software and hardware landscape in the last decade. As a result, software developers must adopt parallelism in order to efficiently make use of multicore CPUs. Task-based scheduling has emerged as one method to reduce the complexity of parallel computing. Although task-based scheduling has been around for many years, the inclusion of task dependencies in OpenMP 4.0 suggests the paradigm will be around for the foreseeable future. While task-based schedulers simplify the process of parallel software development, they can obfuscate the performance characteristics of the execution of an algorithm. Additionally, they can create a challenge for users to analyze the performance of their software and tune algorithmic parameters accordingly. We will present the basic principles of task-based runtimes as well as two new tools developed to assist engineers developing these runtimes and users employing them to parallelize their workloads. The first is a tool allowing users to simulate the execution of their algorithm. The second is an extension to the common execution trace which includes information about task dependencies.
Overview of anesthesia and anesthetic choices

Anesthesiologists and the anesthesia care team, including Certified Registered Nurse Anesthetists (CRNAs) and Anesthesia Assistants (AAs), work to provide a wide range of perioperative services including preoperative evaluation, intraoperative management, post-operative management, intensive care unit (ICU) care, and acute and chronic pain management. The consultant anesthesiologist will function to some degree in all these roles in each patient he/she takes care of, taking into consideration numerous factors when deciding on an anesthetic plan with the surgeon and patient. This topic discusses an overview of anesthesia and anesthetic choices focusing on intraoperative management and the risks and benefits of anesthetic choices. GOALS OF ANESTHESIA — The primary goal of anesthesia is the maintenance of physiologic homeostasis. This includes monitoring and treatment of cardiovascular, pulmonary, neurologic and renal functions and changes during the perioperative period to minimize adverse outcomes. Optimizing intraoperative physiology may help speed recovery and provide for perioperative organ system protection. Amnesia — Amnesia refers to the lack of memory of the intraoperative and perioperative experience. It is reliably achieved by inducing a state of unconsciousness as a result of general anesthesia. A three year study including 87,361 patients found six patients reporting recall under general anesthesia (incidence 0.0068 percent, or 1 per 14,560) [1]. This is the largest study to date looking at recall under general anesthesia. The rate of 1 in 14,560 is lower than the 0.1 and 0.9 percent rate generally reported in the literature; however, previous studies have generally focused on specific patient populations at higher risk for recall, such as obstetric, trauma or cardiac patients, while this study included a wide range of procedures. Differences may also be due to observer or surveyor bias, and perceived differences in implicit versus explicit awareness. In addition, anesthesiologists now have better tools available for physiologic monitoring, such as end-tidal carbon dioxide (ETCO2), pulse oximetry, and anesthetic gas monitoring, which help define a safe threshold for maximal anesthetic delivery. Emergency surgery for polytrauma carries a higher incidence of recall due to the "lighter" anesthetic used in these unstable patients. Other risk factors for intraoperative awareness include depression, cesarean delivery, and cardiac surgery [2,3]. The most likely cause of awareness is a "lighter" depth of anesthesia, which may be necessary in urgent or emergent inductions in potentially unstable patients in order to maintain blood pressure and organ perfusion. The physiologic reason for increased intraoperative awareness in patients with depressive disorder is not clear, but probably is a result of complex neurochemical
Effect of acute myocardial infarction on serum zinc level

Introduction: Myocardial infarction is a common presentation of coronary artery disease. The diagnosis of acute myocardial infarction (AMI) is of vital importance from the management and prognosis point of view. Objective: The purpose of this study was to investigate serum zinc level in acute myocardial infarction patients and to correlate it with biochemical parameter SGOT. Methods: In the present study 30 patients suffering from acute myocardial infarction were taken as a study group with inclusion & exclusion criteria & were compared with the healthy control group. The serum zinc levels of both the groups were estimated on G.B.C.932 model atomic absorption spectrophotometer. The data were analyzed by student unpaired ttest. Results: The serum zinc level in acute myocardial infarction patients was significantly low as compared to healthy controls. In patients with AMI, there was good correlation between the serum zinc level and the biochemical marker of AMI like SGOT. Conclusion: A fall in plasma zinc is a reliable diagnostic test for acute myocardial infarction, and the extent of the fall has prognostic implications. Oral zinc administration to the patients of AMI may be helpful in the prognosis.
Serum level of vascular endothelial growth factor (VEGF) as an independent prognostic factor in metastatic renal cell carcinoma (MRCC)

5044 Background: The French Immunotherapy Group previously showed that circulating interleukin-6 (IL-6) and VEGF correlate with survival in MRCC patients (pts) (Negrier JCO 2004). We aimed to confirm the prognostic value of IL-6 and VEGF, and to test that of macrophage colony-stimulating factor (M-CSF) and macrophage inflammatory protein 3-alpha (MIP-3a) for survival in MRCC pts of good and intermediate prognoses. Patients and Methods: Pre-treatment samples were obtained from 302 MRCC pts enrolled in 2 parallel multicenter randomized cytokine trials. Baseline serum levels of IL-6, M-CSF, VEGF, and MIP3a were determined by immunoassays; their prognostic value for progression-free survival (PFS) and overall survival (OS) was tested. Characteristics of pts with a 0.15 significance level in univariate analysis (ECOG PS, prior therapy, metastatic sites and biological parameters) were entered in a multivariate Cox model. A backward stepwise procedure discriminated non-influential variables at 0.05 level. Result.
Results of acetabular wiremesh and autograft in protrusio acetabuli

Between 1990 and 2005, 25 acetabular reconstructions in 25 patients were performed using autogenous morcellized bone-graft and acetabular wiremesh due to acetabular bone stock loss. The most frequent preoperative diagnosis in our patients were severe hip arthrosis (50%), and rheumatoid arthritis (15%). The mean follow up was 8.6 years (range 2–15 years). The most frequent long-term complication was the appearence of radiolucent lines. A cemented acetabular cup was used in all cases. Preoperative mean Harris Hip Score was 42.3, rising to 90.6 at follow-up after surgery. None of the patients had any loosening of the acetabular component and only one had radiolucent lines >2mm which did not progress. Kohler's line remained intact in all cases. Results of this study suggests bone-grafting and acetabular wiremesh is an effective and simple method to arrest the progresion of acetabular protrusio.
EVALUATION OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH RHEUMATOID ARTHRITIS

The aim of this study was to evaluate the treatment and adverse effects of rituximab in patients with rheumatoid arthritis refractory by disease-modifying antirheumatic drugs therapies. This is a prospective study involving 50 patients with high activity of rheumatoid arthritis. All patients fulfill the criteria of American College of Rheumatology and the European League Against Rheumatism for the diagnosis of rheumatoid arthritis. These patients were hospitalized in the clinic of Rheumatology and followed as outpatients. Rituximab was administered as a 1000-mg intravenous infusion on days 1 and 15. Before treatment, all patients were with high disease activity, DAS 28 > 5.1, while after treatment with rituximab at 24 weeks, 5 (10%) patients had no improvement, where DAS 28 was > 5.1; 11 (22%) patients had partial improvement, where DAS 28 was 3.2; 34 (68%) patients had significant improvement where DAS 28 was < 3.2. Treatment with rituximab in patients with rheumatoid arthritis refractory by Disease-modifying antirheumatic drugs therapies is effective, tolerabe and stable by controlling the symptoms of the disease and prevent progression of articular damage. Some patients have required repetition of the treatment with rituximab after 6 or 12 months, according to the activity of the disease.
Experience-based cortical plasticity in object category representation

Een wetenschappelijke proeve op het gebied van de sociale wetenschappen Proefschrift ter verkrijging van de graad van doctor aan de Radboud Universiteit Nijmegen op gezag van de rector magnificus prof. mr. Contents Chapter 1 General introduction and outline 9 Chapter 2 Birds of a feather flock together: Experience-driven formation of visual object categories in human ventral temporal cortex 21 Chapter 3 Formation of category representations in superior temporal sulcus 4 3 Chapter 4 Category training induces crossmodal object representations in the adult human brain 6 1 Chapter 5 Task-and experience-dependent cortical selectivity to features informative for categorization 8 5 Chapter 6 Summary and discussion 107 Chapter 7 Nederlandse samenvatting 113 Acknowledgements 122 Biography 123 List of publications 123 Donders Graduate School for Cognitive Neuroscience Series 124 General introduction and outline 1 10 General introduction and outline R ecognizing objects and categorizing them starts already at a very young age and continues throughout adulthood. Experience continuously shapes the borders of existing categories and creates even entirely new categories. As such we can easily assign a novel instance of a known object to its category and at the same time we can discriminate between objects that look similar but are in fact different exemplars of the same category e.g. a pear and an apple. This shows that our visual system is capable of both generalization and discrimination. These are the key points of categorization. Moreover, when more skilled in recognizing fruit, for example because of working in the fruit department of a grocery store, one might even be able to distinguish a Bartlett pear from an Anjou pear (Fig 1.1). This suggests that the neural representation of object categories is plastic, and changes as a result of experience. The research in this thesis was designed to investigate experience-dependent plasticity in the representation of object categories. In the experiments in this thesis subjects were trained to differentiate between categories of computer-generated birds (Chapters 2, 3, and 4) and fish (Chapter 5). These stimuli are very difficult to distinguish without any form of training. We used behavioural measures in combination with a non-invasive brain imaging technique (functional magnetic resonance imaging, see box 1) to get insight on experience-based changes in cortical representations. Figure 1.1 It is easier to discriminate between an apple and a pear as between two types of pears. Categorization Categorization takes place at several levels of abstraction (Rosch, Mervis, Gray, Johnson, …
Incivility Among Nurses - Prevalence and Impact

Title: Incivility among nurses – prevalence and impact. Incivility, horizontal violence, uncivil behavior or bullying are only a few terms used to describe the conduct one individual may display toward another that are undesirable in healthcare organizations and consequently gained the attention of regulatory agencies, such as The Joint Commission. Incivility adversely affects healthy work environments, impedes with patient safety and collaboration, has negative financial implications for organizations, and represents an ethical concern in nursing. The purpose of this study was to identify the overall prevalence as well as prevalence based on work areas. In addition, further aims were to examine the likelihood of the study participants calling in sick and/or leaving the organization/department. The study design was descriptive correlational and utilized a web-based survey distributed to 581 nurses (577 registered nurses and 4 licensed practical nurses) at a 258bed acute care facility in Western North Carolina. The sample (n= 153) was obtained via non-random convenient sampling. The assessment tool was based on the Horizontal Survey, which was used and modified with the author’s permission. Descriptive and correlational statistics revealed the General Medical Unit to have the highest prevalence (M = 4.1, SD = 0.8) in this sample. No correlation was found between the experience of incivility and work absences, whereas, the subjects’ expressed thought calling in sick showed a weak correlation to the subjects’ active job seeking (r = 0.567). The findings of this study may assist nurse leaders in creating improved work environments as well as inform future research.
Semantic query optimization in Datalog programs (extended abstract)

Semantic query optimization refers to the process of using integrity constraints (ic ‘s) in order to optimize the evaluation of queries. The process is well understood in the case of unions of select-project-join queries (i. e., nonrecursive datalog). For arbitrary datalog programs, however, the issue has largely remained an unsolved problem. This paper studies this problem and shows when semantic query optimization can be completely done in recursive rules provided that order constraints and negated EDB subgoals appear only in the recursive rules, but not in the it’s. If either order constraints or negated EDB subgoals are introduced in it’s, then the problem of semantic query optimization becomes undecidable. Since semantic query optimization is closely related to the containment problem of a datalog program in a union of conjunctive queries, our results also imply new decidability and undecidability results for that problem when order constraints and negated EDB subgoals are used.
2-(4-Chlorophenyl)-N-(1,3-thiazol-2-yl)acetamide

In the title compound, C11H9ClN2OS, the thiazole ring is nearly planar (r.m.s. deviation = 0.003 Å) and forms a dihedral angle of 64.18 (7)° with the bezene ring. In the crystal, inversion dimers linked by pairs of N—H⋯Nt (t = thiazole) hydrogen bonds generate R 2 2(8) loops.
Diagnostic Value of Stress Radiography in Lesions of the Lateral Ligaments of the Ankle

The diagnostic accuracy of inversion and anterior stress radiography in rupture of the lateral ligaments of the ankle joint was assessed in 56 patients undergoing surgery. In inversion stress radiography, 58 per cent of the patients with confirmed rupture of the lateral ligaments of the ankle had a talar tilt of 10 degrees or more, allowing a predictive value of a positive test of 94 per cent. In anterior stress radiography, 53 per cent of the patients had a posterior tibiotalar distance of 9 mm or more, allowing a predictive value of a positive test of 81 per cent. In measurements of talar tilt and anterior displacement of the talus values higher than normal in the injured ankle may be a sign of a rupture of the lateral ligament.
Optimal nature-walking gait for humanoid robot using Jaya optimization algorithm

This article proposes a new method used to optimize the design process of nature-walking gait generator that permits biped robot to stably and naturally walk with preset foot-lift magnitude. The new Jaya optimization algorithm is innovatively applied to optimize the biped gait four key parameters initiatively applied to ensure the uncertain nonlinear humanoid robot walks robustly and steadily. The efficiency of the proposed Jaya-based identification approach is compared with the central force optimization and improved differential evolution (modified differential evolution) algorithms. The simulation and experimental results tested on the original small-sized biped robot HUBOT-4 convincingly demonstrate that the novel proposed algorithm offers an efficient and stable gait for humanoid robots with precise height of foot-lift value.
MR detectability and appearance of small experimental intracranial hematomas at 1.5 T and 0.5 T: A 6–7-month follow-up study

Purpose: To investigate the detectability and appearance of small experimental intracranial hemorrhages on MR at 0.5 T and 1.5 T in a long-term follow-up. Material and Methods: Autologous blood (1 ml) was injected into the brain of 7 rabbits to create intraparenchymal hematomas. The injected blood leaked partially into the cerebrospinal fluid (CSF) spaces. MR imaging at 0.5 T and 1.5 T were performed immediately before and after hematoma creation, at 2 weeks and monthly up to 6 or 7 months using T1-, proton density- and T2-weighted (w) spin-echo (SE), FLAIR and T2*-w gradient echo (GE) pulse sequences. Results: Blood was detected both in the brain and in the CSF spaces of all animals during the first hours after hematoma creation at 1.5 T. In the last examination after 6–7 months, the T2*-w GE sequences still showed residues of the intraparenchymal hematomas in all the rabbits at 1.5 T, but the signal pattern was not specific for the age of the hematomas. SE and FLAIR sequences were insensitive. The histopathology revealed iron deposits in all brains. Conclusion: Residues of small intraparenchymal hematomas can be seen for months with T2*-w GE sequences on brain MR imaging at 1.5 T. The age of the microhematomas cannot be estimated with MR imaging.
Arthroscopic Reduction and Percutaneous Fixation of Scaphoid Fracture and Nonunion

Purpose: To analyze the results of an arthroscopic reduction and percutaneous fixation of scaphoid fracture and nonunion. Materials and Methods: Fourteen scaphoid fractures or nonunion patients were analyzed clinically. There were 13 men and 1 woman, with a mean age of 30 (14-45) years. The average follow-up time was 13 months (12-18). Three cases had delayed union, 5 cases had nonunion and 6 cases had a fracture. After fluoroscopic reduction and an arthroscopic examination, the scaphoid was fixed with an Acutrak screw or K-wire percutaneously. The serial radiographs were checked by 2 weeks to confirm the bony union. The Mayo wrist score and DASH were used to assess the functional result at the final follow up. Results: Bony union was acquired in 13 cases in a mean time of 8 weeks. The mean Mayo wrist score was 86 points (60-100) with 7 excellent, 4 good, 2 fair and 1 poor case. The mean DASH was 11.1 points (0-63.3). Conclusion: In scaphoid fracture and delayed union, good results could be obtained by an arthroscopic reduction and percutaneous fixation. However, in scaphoid nonunion, this technique should only be used in selected cases.
HLA-DRB1* Allele Frequencies in Pediatric, Adolescent and Adult-Onset Multiple Sclerosis Patients, in a Hellenic Sample. Evidence for New and Established Associations

Studies in many populations consistently have showed that the human leukocyte antigens (HLA) and especially the DRB1*15 allele has by far the strongest genetic association with multiple sclerosis (MS). The aim of this study was to investigate the role of HLA-DRB1* alleles in MS risk/resistance and onset. A sample of 165 Hellenic MS patients (18 with pediatric-, 24 with adolescent- and 123 with adult-onset MS) and 107 healthy volunteers were examined with molecular techniques. Comparisons were made according to the Benjamini-Yekutieli method for p value correction. Both adult-onset MS patients and early-onset MS patients (age at onset below 20 years-old) had a significantly higher frequency of the DRB1*15 allele and a significantly lower frequency of the DRB1*11 allele compared to controls. For the early-onset vs. healthy group comparison, subgroup analyses revealed that both the pediatric- and the adolescent-onset MS groups contributed to the aforementioned DRB1*15 significant difference, while the DRB1*11 difference was ascribed solely to the adolescent-MS onset vs. healthy group comparison. Within MS patients comparisons revealed that early-onset MS patients had a tendency for higher DRB1*03 allele and a lower DRB1*16 allele frequency frequencies compared to adult-onset MS patients, although both non-significant. Notably, pediatric-onset MS patients showed complete absence of the DRB1*16 allele, along with a non-significant tendency for higher DRB1*15 allele frequency relative to the adult-onset group. Finally, the adolescent-onset MS group was presented with a lower DRB1*11 allele frequencies compared both to the pediatric- and the adult-onset MS group. Our findings confirm previous studies on the role of HLA-DRB1* in MS. New findings that need to be confirmed by further studies are the pathogenetic role of DRB1*03 for early-onset MS and the putative protective role of the DRB1*16 allele in the pediatric-onset MS.
Treatment of femoral pseudoaneurysms: Percutaneous US-guided thrombin injection versus US-guided compression

Purpose: Thrombin injection in femoral pseudoaneurysms has been suggested to be superior to traditional US-guided compression. Our aim was to evaluate results with compression therapy with special reference to use of thrombin in case of failure. We also studied 7 patients who underwent primary thrombin injection. Material and Methods: We retrospectively reviewed all (n=44) femoral artery pseudoaneurysms diagnosed at our department during October 1998–May 1999. US-guided compression with the Femostop device or US-guided thrombin injection (100–1000 IU) was the first choice according to the physicians' preference, followed by the other regime if the first choice was non-successful. Results: Thirty-nine (89%) of the patients received anticoagulation treatment and/or concomitant antiplatelet drugs. Out of the 44 patients, 37 were treated with compression as the first choice. This regime was successful in 22 (59%). This group included 2 lesions that resolved spontaneously after initially failed compression and 1 deep venous thrombosis after treatment. The persistent 15 pseudoaneurysms after failed compression received thrombin injection, and it was also the primary therapy in 7 patients. Complete thrombosis within the pseudoaneurysm was immediately induced after treatment. One early recurrence required a second injection. No complication of thrombin was noted and no surgery was required. Conclusion: US-guided thrombin injection is an effective treatment for embolisation of pseudoaneurysms. The technique is superior to compression therapy.