Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparison of predictive value of risk scores regarding the short-term and long-term prognosis of patients with acute myocardial infarction treated with primary percutaneous coronary intervention

Introduction: Primary percutaneous coronary intervention (pPCI) presents standard treatment in patients with acute myocardial infarction. In order to predict the prognosis of patients with ST segment elevation myocardial infarction (STEMI), several risk scores have been developed. Aim: Comparison of the predictive value of three validated risk scores, regarding intrahospital, short-term (30-days) and long-term (1-year) mortality among patients with a diagnosis of STEMI treated with pPCI in the Catheterization lab, Clinical Center of Serbia. Material and methods: The retrospective study included 311 consecutive patients with a diagnosis of STEMI treated with pPCI in 2017. Patients with cardiogenic shock at admission were excluded. Data were analyzed from the electronic database. For every patient the value of CADILLAC, ZWOLLE and TIMI score was calculated. The predictive ability of the risk scores was compared by area under (AUC) the ROC (Receiver Operating Characteristic) curves. The short-term and long-term outcome of the patient was assessed by telephone and clinical contact. Results: The study population was 311 patients, with an average age of 61±10 years, of which 237 (76.2%) were male. Rates of intrahospital, mortality at 30 days and at one year after pPCI were 1.9%, 3.2%, 6.1%. All three test scores showed very good predictive value in short-term mortality, both intrahospital (0.962; 0.986; 0.964, p=ns within scores) and after 30 days (0.920; 0.956; 0.861, p=ns within scores), while after 1 year accuracy of CADILLAC and ZWOLLE was better than TIMI score (0.921; 0.905; 0.786, p vs. TIMI 0,0087 and 0,0567). The age, three-vessel coronary disease and lower admission hemoglobin were identified as independent predictors for one-year mortality by logistic regression analysis. Conclusion: Both CADILLAC and ZWOLLE showed a very good predictive ability for intrahospital, short and long-term mortality, while for TIMI score, comparable accuracy was observed only for a period of up to 30 days following pPCI.
Study of drying kinetics of salmon processing by-products at different temperatures and the quality of extracted fish oil

ABSTRACT Samples of salmon processing by-products were minced, mixed, and partially dried to moisture content of 90 ± 5% (dry basis), at two different temperatures 60 and 100°C (using hot air-drying and oven-drying, respectively). Theoretical and semitheoretical drying models were used for modeling of the drying kinetics of salmon by-products mix, where Page model and logarithmic models were observed as the best models presenting the drying kinetics of salmon by-products at 60 and 100°C, respectively. Salmon by-product oil was extracted from the partially dried by-product through centrifugation and was compared with enzymatically extracted (enzymatic extraction method was considered as the control method) salmon oil, in terms of fatty acid profile of the oils. The oil content obtained through semidried samples and enzymatically treated samples ranged between 16.234 and 18.212 g/100 g of fresh sample, which were not significantly different. The fatty acid composition was similar in all the cases. The fatty acids predominantly observed in the salmon oils included oleic acid, linoleic acid, and palmitic acid. Other fatty acids included palmitoleic acid, stearic acid, vaccenic acid, gondoic acid, and myristic acid. Docosahexaenoic acid and eicosapentaenoic acid contents were between 1 and 2% of the oil extracted in all the cases, and DPA (Docosapentaenoic acid) content was approximately 1%. Hence, partial dehydration at both the temperatures was concluded as a potential processing method for increasing the storability of salmon by-products and obtaining salmon oil with high quality.
What makes learning enjoyable Perspectives of today s college students in the U.S. and Brazil

The purpose of this article is to uncover what makes learning enjoyable for Generation Z college students (born 1995-2010) in the United States (U.S.) and Brazil. Qualitative data from 1,282 participants in the U.S. and 775 participants in Brazil were analyzed independently and for comparison using content analysis and thematic coding. The results of this study show both similarities and differences between these two populations. Both groups enjoy learning that is interesting, inspiring, relevant, and engaging. U.S. students enjoy knowledge acquisition, learning for societal impact, and having instructors who are competent and relatable. Brazil students, on the other hand, enjoy peer learning. While these results align with previous research findings on preferences for learning and cultural nuances, it is important to note that studies on Generation Z college students and learning are sparse. Thus, understanding this generational cohort in higher education is paramount for both informing and supporting individual pedagogical practices and shaping training initiatives on teaching and learning in higher education. In addition, given the impact of globalization on technology, commerce, entertainment, and information, uncovering the similarities in how young people from different cultures perceive learning may have global implications on research, training, and individual instruction in a more macro and universal way.
Diagnostic technique for analysing the internal faults within power transformers based on sweep frequency response using adjusted R-square methodology

The sweep frequency response analysis (SFRA) technique is based on measuring the power transformer electrical transfer functions over a wide frequency range to identify the abnormal areas prior to serious failure. This study presents the proposed diagnostic adjusted R-square technique to identify the transformer faults using the SFRA technique. The SFRA measurements are ranged up to and beyond 1 MHz. The proposed technique is used to calculate the relative factor for adjusted R-square coefficient between the actual data and new measurement data sets. The results of the proposed method are evaluated and compared with existing Chinese Standard factor DL/T 911-2016 and CCF factor of IEEE Std. C57.149™ Standard indicates that the suggested methodology is more reliable to identify and analyse the internal faults of the transformers. This technique is considered to be effective indicator to predict the internal physical condition inside the transformer, which moves the field forward.
Thermosensitive Nasal In Situ Gels of Lipid-Based Nanosystems to Improve the Treatment of Alzheimer’s Disease

Thermosensitive in situ gels are promising formulations for the management of Alzheimer’s disease (AD), since they increase the residence time of lipid-based nanosystems in the nasal cavity, improving drug therapeutic efficacy. The purpose of this study is to prepare thermosensitive in situ gels with anticholinesterase inhibitor (RVG)-loaded nanostructured lipid carriers (NLC) and nanoemulsions to improve the residence time of the formulations in the nasal cavity. Different concentrations of thermosensitive polymers were added to the RVG-loaded NLC and to the RVG-loaded nanoemulsion to optimize the gelation temperature of the in situ gels; concentrations of 17% (%, w/w) of Kolliphor® P407 and 0.3% (%, w/w) of MethocelTM K4M were selected. The in situ gels of the RVG-loaded NLC and RVG-loaded nanoemulsion had a particle size, PDI, ZP, and pH of, respectively: 141.70 ± 0.40 nm and 146.10 ± 1.73 nm; 0.45 ± 0.00 and 0.43 ± 0.02; −4.06 ± 1.03 mV and −4.09 ± 0.71 mV, 6.60 ± 0.01 and 7.00 ± 0.02. In addition, these in situ gels showed a non-Newtonian plastic behavior, and the texture parameters presented desirable values for nasal administration. From these results, we concluded that the developed in situ gels can be used to improve the treatment of AD through the nose-to-brain route.
Water Quality as a Food Safety Special Issue on Cruise Ships: Applied to Cruises in the Governorates of Luxor and Aswan

Cruises in Egypt have a distinguished international reputation and even in the critical times that Egyptian tourism suffered, these cruises were on the River Nile filled up with tourists coming to them from every part of the world. However, cruise customers can be exposed to dangerous situations involving water borne illnesses. The objectives of the study are to reveal the current water quality situation, investigate the interaction of activities and water quality, and their effects on food safety and human health. The results got fresh water for ships in one of two ways: by producing it onboard by mean (4.58) or by acquiring it from local sources in ports by mean (4.71). The research results were obtained through the questionnaires distribution, as well as obtaining a water sample and analyzing it both microbiologically and chemically. The results of this study showed that the extent of water hygiene and safety in floating hotels in Luxor and Aswan governorates, and the impact of using that water on the health of the inmates, and sources of pollution. (131) questionnaires were distributed to floating hotel managers, while (86) questionnaires were retrieved by (65.6%). To measure the extent of awareness and attention to water quality in floating hotels in the governorates of Luxor and Aswan and highlight the sources of pollution in order to pay attention to the health and safety of inmates and workers. A random water sample was obtained from a cruise to ensure the health and safety of water that used on a board of cruises. It has already been proven that there are no microbes, and the report has already confirmed that the water sample is suitable for human consumption. While, the bacteriological analysis of water was done by a medical analysis laboratory, expert in microbiologically and chemically analysis.
Challenges of Small- and Medium-Sized Enterprises (SMEs) in Business Growth: A Case of Footwear Industry

Small- and medium-sized enterprises (SMEs) create more employment opportunities and thus, contribute to the national economy of a country. Footwear SMEs have been identified as an emerging economy in Bangladesh, which is facing several challenges. Very few studies focused on the challenges of SMEs’ business growth. However, until now, no literature particularly focused on the challenges of footwear SMEs and discussed how to tackle these challenges. To fill this research gap, we use the Fuzzy Delphi Method and fuzzy analytical hierarchy process, to find out the degree of importance of critical challenges of footwear SMEs. In our study, 16 critical challenges are identified among which lingering in cash flow (F3), fierce market competition (E1), access to finance (F2), unfavorable bank loan policy (F1), and poor supply chain management (E2) have been ascertained as the top five critical challenges, respectively. This study contributes to the existing literature of SMEs by identifying five new challenges from the context of the footwear industry. Furthermore, we suggest some possible measures to overcome the identified challenges. This study can guide the government, practitioners, and SME policymakers to address these challenges for the growth of any SME sector.
Chemical, Volatile Profile and Shelf Life of Muffin Enriched with Supplementation Chestnut Cream

The supplementation of chestnut cream in a new muffin formulation was investigated to evaluate the use of chestnut derivatives in baked goods. To assess the muffins qualities, with and without potassium sorbate, were evaluated the physical-chemical properties, fatty acids and volatile organic compounds (VOCs) profiles and shelf life (30 days). The fatty acid composition showed that the highest concentrations were evidenced for linoleic acid (47.3%), oleic acid (30.4%) and palmitic acid (14.2%). The total microbial count (TMC), yeasts and molds loads increased during the storage but remained under limit imposed by law. The VOCs detected are produced during baking process as a result of thermally induced reactions while phenolic compounds could derive from the chestnut cream. The electronic nose results showed that the “fingerprints” of VOCs are not overlapping, confirming the HS-SPME-GC/MS data. According to the results, the formulation of new muffin could expand the array of commodities and further enlarge, the market for chestnut derivatives. Practical Application The introduction of the new sweet chestnut cream muffin formulation could represent a chance to increase the use of chestnut derivatives and could be alternative ingredients in baked goods. In fact, the supplementation of chestnut cream may give interesting properties as better physico-chemical properties, fatty acids, volatile organic compounds and a good shelf life. Moreover, they preserve the nutritional characteristics of the starting fruit.
Top-Seeded Solution Growth and Optical Properties of Deep-UV Birefringent Crystal Ba2Ca(B3O6)2

Single crystals of the birefringent material Ba2Ca(B3O6)2 (BCBO) with dimensions up to 40 × 28 × 10 mm3 were successfully grown by top-seeded solution growth (TSSG) method from B2O3–NaF flux. It exhibits high transmittance in the range of 190–3000 nm with UV cutoff of 178 nm, which is much shorter than that (189 nm) of the commercial UV birefringent crystal, the high-temperature phase of BaB2O4 (α-BBO). Meanwhile, BCBO crystal has large birefringence (Δn = no – ne = 0.2524–0.0862) in the wavelength range from 178 to 3000 nm and without phase transition from room temperature to the melting point. A prototype of Glan–Taylor polarizer made from BCBO crystal showed an optical extinction ratio of 104:1, which is comparable to those of commercial birefringence crystals. The experimental results demonstrate that the BCBO crystal can be a new promising birefringent crystal for UV, especially the sub-200 nm deep-UV range.
Sustainable Competitive Advantages of Chinese Online Travel Agents: Analysis Based on RBV View

Chinese Online Tourism Agents (OTAs) are facing with fierce competition currently. Therefore, it is of primary importance for Chinese OTAs to build long lasting competitive advantages. This study identifies the sustainable competitive advantages of Chinese Online Tourism Agents (OTAs) based on the resource-based perspective. The study conducted an online questionnaire survey among 210 consumers who were randomly chosen from six OTAs in China. Five competitive advantages were identified from the survey: payment model, product variety, cost leadership, service responsiveness and e-marketing strategies. Recommendations in terms of system security, service customization and corporate social responsibilities were put forward based on the perceived shortcomings of the OTAs.
Design of 9:2 compressor using FinFET

Multiplier is an essential component that is used commonly in any digital circuits. In general, for any digital circuits, multipliers occupy larger area; have long latency and their power consumption is more. Thereby, enhancing the performance of multipliers is quite important. Compressors are used to reduce the partial products so that the improved performance of multipliers can be achieved. In this paper, a new structure of 9:2 compressor is proposed in which the circuit is implemented with different combinations of 3:2, 4:2, 5:2 and 6:2 compressors. In this work, instead of bulk CMOS technology, circuits are implemented using FINFETs as they provide better gate control property, lower short channel effects. All the compressor circuits have been implemented using Cadence Virtuoso Simulator with FINFET 32nm technology. All the circuits are implemented to analyze the performance in terms of power, delay and transistor count.
Mechanistic studies of rep D, a staphylococcal plasmid replication initiator protein

The DMA sequences of many small s taphylococcal plasmids possess open reading frames with 70-80% sequence id en ti ty to th a t of the repD product of the ch loramphen ico 1-res is tance plasmid pC221. This th e s is describes the r e s u l t s of s tu d ie s of the REP D pro te in , requ ired fo r in i t ia t io n of re p l ic a t io n of pC221 both in vivo and in v itro . REP D was expressed in Escherichia co li, using a p u rp o se -b u il t expression vector, as 10-15% of the to t a l c e l lu la r p ro te in . P u r if ic a t io n y ie ld s 40-50mg of REP D from one l i t r e of induced cu l tu re . The p ro te in d isp lays a molecular weight of 35 kDa on denaturing g e l e lec tro p h o re s is , in c lose agreement with th a t p red ic ted from the DNA sequence, and 75 kDa by ge l f i l t r a t i o n of the na tive form, sugges ting a dimeric quaternary s t r u c tu re . N -terminal amino acid sequence ana ly s is of REP D revealed the absence of the presumed in i t i a to r methionine res idue . In v i tr o REP D has both sequence-spec if ic endonuclease and ty p e -I topoisomerase a c t iv i t i e s . The ta rg e t is oriD, the re p l ic a t io n o r ig in of pC221, contained within the repD reading frame. Supercoiled pC221 and plasmids with r e la te d o rig in sequences (such as pT181) a re relaxed by REP D in high ionic s t re n g th bu ffe rs , whereas relaxed, covalently closed plasmid pC221 only is nicked by REP D a t a p rec ise location in the (+) s tran d (oriU) under conditions of low ionic s t ren g th . Both reac tio n s requ ire Mĝ * but no t ATP. Binding of REP D to oriD was demonstrated, using r e s t r i c t i o n fragments of pC221 and sy n th e t ic o ligonucleo tides . Competition experiments su g g es t two DNA binding s i t e s . The f i r s t is involved in the recognition of the conserved cleavage s i t e . The second s i t e d iscrim inates between such p o te n t ia l o r ig in s by binding only to a "spec if ic i ty " sequence p resen t within oriD. A fter nicking the relaxed o rig in DNA s u b s t r a te REP D is found to be covalently a t tached to the r e s u l t a n t 5 ' end. Radio label ling and hydro lysis revealed the linkage to be via a phosphodiester bond to a ty ros ine res idue . Peptide sequencing iden tif ied the ty rosine to be Tyrl88 of REP D, conserved in the sequences of a l l s ix re la te d REP p ro te in s known. A mechanism for in i t ia t io n of plasmid re p l ic a t io n is suggested on the b as is of these r e s u l t s . The nicking reac tion is thought to t r ig g e r the in i t i a t io n of rep l ica t io n of pC221, the f ree 3 ' hydroxyl group genera ted priming sy n th es is of the new (+) s trand . The requirement in v i tr o fo r a relaxed s u b s t r a te to demonstrate the abso lu te sequence s p e c if ic i ty seen in vivo su g g es ts the local topology of the o rig in region may have low superhe lica l density in vivo.
In situ growth of large-area and self-aligned graphene nanoribbon arrays on liquid metal

Abstract Intrinsic graphene features semi-metallic characteristics that limit its applications in electronic devices, whereas graphene nanoribbons (GNRs) are promising semiconductors because of their bandgap-opening feature. However, the controllable mass-fabrication of high-quality GNR arrays remains a major challenge. In particular, the in situ growth of GNR arrays through template-free chemical vapor deposition (CVD) has not been realized. Herein, we report a template-free CVD strategy to grow large-area, high-quality and self-aligned GNR arrays on liquid copper surface. The width of as-grown GNR could be optimized to sub-10 nm with aspect ratio up to 387, which is higher than those of reported CVD-GNRs. The study of the growth mechanism indicates that a unique comb-like etching-regulated growth process caused by a trace hydrogen flow guides the formation of the mass-produced self-aligned GNR arrays. Our approach is operationally simple and efficient, offering an assurance for the use of GNR arrays in integrated circuits.
An Integrated Approach to the Design of Centralized and Decentralized Biorefineries with Environmental, Safety, and Economic Objectives

Biorefineries provide economic, environmental, and social benefits towards sustainable development. Because of the relatively small size of typical biorefineries compared to oil and gas processes, it is necessary to evaluate the options of decentralized (or distributed) plants that are constructed near the biomass resources and product markets versus centralized (or consolidated) facilities that collect biomass from different regions and distribute the products to the markets, benefiting from the economy of scale but suffering from the additional transportation costs. The problem is further compounded when, in addition to the economic factors, environmental and safety aspects are considered. This work presents an integrated approach to the design of biorefining facilities while considering the centralized and decentralized options and the economic, environmental, and safety objectives. A superstructure representation is constructed to embed the various options of interest. A mathematical programming formulation is developed to transform the problem into an optimization problem. A new correlation is developed to estimate the capital cost of biorefineries and to facilitate the inclusion of the economic functions in the optimization program without committing to the type of technology or the size of the plant. A new metric called Total Process Risk is also introduced to evaluate the relative risk of the process. Life cycle analysis is applied to evaluate environmental emissions. The environmental and safety objectives are used to establish tradeoffs with the economic objectives. A case study is solved to illustrate the value and applicability of the proposed approach.
CPU utilization prediction method based on composite model

The business system server under the big data environment is always faced with a large number of data services, which makes the performance of its core hardware CPU face a serious test. Therefore, the prediction of server CPU utilization is of great significance in server resource allocation. In response to this situation, a method of server CPU utilization prediction based on ARMA-BiLSTM composite model is proposed. In this method, the original CPU utilization data is decomposed by wavelet decomposition, and the trend item and the detail item of CPU utilization data are obtained. Based on the Bi-LSTM neural network model, the trend item is modeled and predicted, and the detail item is modeled and predicted using the ARMA model. The prediction results of the two are added together to obtain the final prediction result. Through experimental verification, the proposed prediction model has higher accuracy than traditional models.
An Integrated Design and Fabrication Strategy for Planar Soft Dielectric Elastomer Actuators

Dielectric elastomers (DEs) are promising soft actuators for use in soft material robots, due to their considerable voltage-induced strain. The actuator's behavior is highly nonlinear due to the complex interplay between the DE, the support structure, and the input electric field, making it a big challenge to automatically design dielectric elastomer actuators (DEAs). Here, in this article, we present an integrated design strategy for planar DEAs, aiming to realize their full potential. To endow the actuator module with the maximal actuation strain, we carry out dimensionless analysis to identify the key design variables, develop a fast finite element analysis model, and thoroughly investigate how the geometric structuring and the material prestretch tailor the voltage-induced deformation. We also provide a fabrication strategy by patterning the compliant electrodes on the DE membrane and then directly printing the support structure made of thermoplastic polyurethane. The experiments show that the optimized actuator obtains a remarkable nominal strain up to 38.6%. We also characterize the dynamic performance of the optimized actuator, evaluate its energy density and power density, and develop a soft locomotion robot that can crawl through a confined tunnel, at a fast moving speed up to 0.17 body length/s.