Miracle-dz/UniFAR-FTUs huggingface dataset:
Risk factors of Metabolic Syndrome and Lifestyle in Early Adulthood in Korea

The objective of this study was to identify risk factors of metabolic syndrome in early adulthood which has currently shown an increase in Korea, due to a westernized lifestyle. Health medical examination data collected from a total of 5801 participants, gathered by the National Health Insurance Service(NHIS) in 2013, was used to proceed with the study. NCEP ATP-III was used as diagnostic criteria for determining metabolic syndrome. The prevalence rate for metabolic syndrome totaled 32.8%, 29.7% for men and 3.1% for women. Among the subjects, 21.5% of men were found to have abnormal waist circumferences compared to a percentage of 2.3% for women. However, the HDL-cholesterol levels for both men and women were very similar, at 13.6% and 13.3% respectively. There were statistically significant differences in their BMIs, family histories of diabetes, smoking periods, smoking frequencies, alcohol consumption, drinking frequencies, and intense physical activities for the metabolic syndrome group and the normal group. The factors influencing metabolic syndrome were BMI(OR=1.645, 95% CI, 1.599-1.692), a high risk of diabetes(OR=8.818, 95% CI, 4.493-17.306), drinking frequency(OR=1.151, 95% CI, 1.074-1.233), smoking period(OR=1.037, 95% CI, 1.010-1.064), whereas the family history of diabetes, smoking frequency, and physical activity showed no significance. The factors attributing to a high risk in diabetes were BMI(OR=1.021, 95% CI, 1.008-1.035), family history of diabetes(OR=1.835, 95% CI, 1.045-3.225), smoking period(OR=1.125, 95% CI, 1.050-1.206), presence of metabolic syndrome(OR=8.519, 95% CI, 4.876-14.885). The result from the data illustrates the necessity in developing programs and management education for such factors (BMI, smoking, drinking) that influence metabolic syndrome in early adulthood. Promotion of the environment and social awareness of metabolic syndrome is also required to make possible improvements in lifestyle.
A nationwide analysis of US racial/ethnic disparities in smoking behaviors, smoking cessation, and cessation-related factors.

OBJECTIVES We used nationally representative data to examine racial/ethnic disparities in smoking behaviors, smoking cessation, and factors associated with cessation among US adults. METHODS We analyzed data on adults aged 20 to 64 years from the 2003 Tobacco Use Supplement to the Current Population Survey, and we examined associations by fitting adjusted logistic regression models to the data. RESULTS Compared with non-Hispanic Whites, smaller proportions of African Americans, Asian Americans/Pacific Islanders, and Hispanics/Latinos had ever smoked. Significantly fewer African Americans reported long-term quitting. Racial/ethnic minorities were more likely to be light and intermittent smokers and less likely to smoke within 30 minutes of waking. Adjusted models revealed that racial/ethnic minorities were not less likely to receive advice from health professionals to quit smoking, but they were less likely to use nicotine replacement therapy. CONCLUSIONS Specific needs and ideal program focuses for cessation may vary across racial/ethnic groups, such that approaches tailored by race/ethnicity might be optimal. Traditional conceptualizations of cigarette addiction and the quitting process may need to be revised for racial/ethnic minority smokers.
Design for X (DfX) in the Internet of Things (IoT)

Designing quality in is a cornerstone of modern quality management philosophies. Design for X (DfX) techniques provide guidelines, heuristics, and metrics to ensure that a particular quality attribute exists in a design. Although hundreds of papers have been published on DfX approaches, few researchers have explored systematically applying multiple DfX in a particular problem context. As the Internet of Things (IoT) evolves, boundaries between people, computers, and objects will become less distinct, underscoring the need for more holistic design. Using mixed methods, this paper examines the utility of DfX in the emerging IoT ecosystem. We identify DfX that are applicable to IoT-related design, and find gaps that demand further research and development. The results from this study can be used to help designers and quality managers select or develop appropriate DfX to use in designing components for the Internet of Things (IoT), supporting actionable strategies for quality and customer satisfaction.
Pharmacologic Management of Alcohol Use Disorders in the Primary Care Setting

Objective:��Toexaminetherationaleandevidence� tosupportpharmacotherapiestotreatalcoholprob- lemsintheprimarycaresetting. � •� Methods:��Qualitativereviewoftheliterature. •� Results:��Problemalcoholconsumptionisapreva- lentproblemintheUnitedStatesandresultsin� significantmorbidityandmortality. Inrecentyears,� newpharmacologictreatmentshavebeenapproved� bytheU.S. �FoodandDrugAdministrationtohelp� healthcareproviderstreatpatientswithalcohol� problems. �Theavailableresearchhasshownthatdi- sulfiram,�naltrexone,�andacamprosateareeffective� fortreatingpatientswithalcoholproblems. �Certain� patientcharacteristicspromoteenhancedoutcomes� foreachmedication. �Whethercombinationsofphar- macotherapiesorcombinationsofpharmacotherapy� withnonpharmacotherapyenhanceoutcomesfor� problemdrinkersareactiveresearchtopics. � •� Conclusion:��Primarycareprovidersshouldstrongly� considertheuseofpharmacologictreatmentasan� adjuncttononpharmacologictherapytohelppa- tientsreduceoreliminatealcoholconsumption.
Methods for a Multisite Randomized Trial to Investigate the Effect of Constraint-Induced Movement Therapy in Improving Upper Extremity Function among Adults Recovering from a Cerebrovascular Stroke

This article describes the study design, methodological considerations, and demographic characteristics of a phase III RCT to determine if 1) constraint-induced therapy (CI therapy) can be applied with therapeutic success 3 to 9 months after stroke across different sites, 2) gains that might occur persist over 2 years, 3) initial level of motor ability determines responsiveness to CI therapy, and 4) the treatment effect differs between those treated before 9 months and after 1 year. Six sites will screen and recruit poststroke survivors stratified on initial level of motor ability and after randomization allocate participants to immediate or delayed intervention. Primary outcomes include a laboratory-based measure of function (Wolf Motor Function Test [WMFT]) and a real-world participant-centered functional use measure (Motor Activity Log [MAL]). Secondary outcomes concern function, behavior, and compliance. This is the first multisite, single-blind RCT of a formal training intervention for upper extremity rehabilitation in subacute stroke in the United States.
Critical evaluation of the different staging systems for hepatocellular carcinoma

Diagnostic and therapeutic options for hepatocellular carcinoma (HCC) have improved substantially in recent years. A number of new palliative and potentially curative treatment strategies are now available. However, evaluation of the therapeutic modalities and assessment of the prognosis of HCC remain difficult owing to the lack of consensus on a single staging system and the availability of a number of new staging systems, each claiming to be the most appropriate.
Absolute lymphocyte count recovery at 1 month after transplantation predicts favorable outcomes of patients with hepatocellular carcinoma

Absolute lymphocyte count (ALC) and the recovery of ALC after treatment have been identified as a prognostic biomarker for several malignancies. In this study, we aimed to investigate the prognostic role of peritransplant ALC and ALC recovery after liver transplantation (LT) in hepatocellular carcinoma (HCC) patients.
Screening Methods in Prevention of Cervical Cancer

Screening is a public health activity to detect disease among people thought a priori to be well. In the United States, the major cervical screening target is treatable CIN3 (or, to be especially cautious, CIN2), not invasive cervical cancer, for which treatment causes far more morbidity and is less certain to succeed. Therefore, cervical screening distinguishes between the few women who might become patients because they are at highest risk of cancer and the overwhelming majority of women who are at far lower risk. Screening that targets the common, minor, and typically benign cytological and histological evidence of acute HPV infection cannot be cost-effective because the risk of invasive cancer is so low However, finding a woman with CIN3 is considered a screening success because she has a high risk of invasive cancer and can be treated before cancer develops.demonstrated in Nordic countries and in the United Kingdom (Bulkmans et al., 2005; Sasieni & Adams, 1999.)
Characterization of Hypertrophic Cardiomyopathy Using Magnetic Resonance “ Fibrosis ” Imaging

Hypertrophic Cardiomyopathy (HCM) affects one in five hundred people in the United States. It is historically recognized by abnormal patterns of hypertrophy in at risk populations. However, from its first description fibrosis of the myocardium has been integrally linked to the disease, its clinical manifestations and its progress. Magnetic Resonance Imaging allows non-invasive realization of this fibrosis and may improve early diagnosis, improve our understanding of the true prevalence of disease as well as risk assessment while offering the opportunity for recognition and perhaps treatment of pre-clinical disease.
Simultaneous SIL‐TAL1 RT‐PCR detection of all tald deletions and identification of novel tald variants

Site‐specific deletions of the 5′ part of the TAL1 gene (tal d ) are among the most frequent non‐random genetic abnormalities in T‐cell acute lymphoblastic leukaemia (T‐ALL). They are usually detected by PCR from DNA with several primer pairs or by Southern blot analysis. Since tald lead to expression of a SIL‐TAL1 fusion transcript, irrespective of the genomic breakpoint, we have used a single monoplex RT‐PCR reaction to screen 55 T‐ALL patients at diagnosis. SIL‐TAL1 transcripts were demonstrated in 12 (22%) cases, including 7/27 (26%) children <15 years of age, 2/8 (25%) adolescents and 2/17 (12%) adults aged >20 years. SIL‐TAL1 RT‐PCR was preferrable to tal d DNA PCR since it allowed the simultaneous detection of tal d1, tal d2 and two previously undescribed tal d variants. SIL‐TAL1 RT‐PCR screening should therefore increase the detection rate of tal d by approximately 15–20%, with an at least comparable sensitivity to tal d genomic PCR, and represents a more practical and economic alternative to multiple DNA PCRs or Southern blotting when incorporated into molecular screening for multiple transcripts at diagnosis.
Fluctuation strength analysis of a long-range opinion model

In this paper, we provide a bounded-confidence opinion model and focus on the study of the fluctuation strength resulting from fluctuating opinions' long-range interactions. In our model, there are stubborn agents and regular agents, where each stubborn agent never changes its opinion but a regular agent updates its opinion using other agents' opinion values according to its confidence bound. We show the fluctuation phenomena of this model and provide an estimation of the fluctuation strength of this opinion model based on some parameters.
BASIC SCIENCE REVIEW

The epidermal growth factor receptor (EGFR) has been shown to be a promising therapeutic target in head and neck cancer. Cetuximab, a monoclonal antibody against EGFR, has been approved in the United States for use with radiotherapy for head and neck squamous cell carcinoma. However, the role of EGFR targeting agents in other therapeutic modalities, such as combined chemoradiotherapy or induction chemotherapy, remains to be defined. Although results from several clinical trials have demonstrated the therapeutic potentials of EGFR targeting agents in these settings, further studies are necessary before definitive conclusions can be made. The concurrent targeting of EGFR along with other pathways important in carcinogenesis may hold significant therapeutic potential. In particular, several clinical trials are studying the effects of combining agents that target the vascular endothelial growth factor with EGFR inhibitors. Last, studies are ongoing to elucidate the predictive and correlative biomarkers in anti-EGFR therapy to allow for proper patient selection. In the case of cetuximab, these correlative biomarkers may include elements of the immune system in addition to the signal transduction proteins involved in EGFR pathway. VC 2008 Wiley Periodicals, Inc. Head Neck 30: 667– 674, 2008
Suicides et troubles mentaux chez des hommes incarcérés : faut-il en appeler à une prise en charge communautaire ?

L'article porte sur un echantillon de 243 hommes incarceres dans deux villes differentes, echantillon au sein duquel on retrouve des taux eleves d'antecedents suicidaires et de troubles mentaux. Les niveaux de gravite, d'urgence et de risque suicidaires caracterisant ce groupe d'hommes etaient egalement eleves. Des 243 detenus a l'etude, 43 (17,7 %) presentaient une urgence suicidaire elevee et/ou un trouble mental grave. L'analyse des dossiers institutionnels de ces individus en difficulte a revele que seulement 35 % d'entre eux avaient ete depistes formellement, mais que 75 % avaient au moins ete identifies informellement. Les dossiers etaient peu annotes et ne rendaient peut-etre pas justice au travail clinique qui n'est pas toujours consigne. Ce manque d'informations pouvait neanmoins laisser entrevoir un probleme au niveau du suivi des individus. Par ailleurs, de grandes differences etaient observees entre les detenus des deux villes. Les services psychiatriques et de dejudiciarisation offerts dans les communautes respectives pourraient expliquer ces differences en ce qui concerne les prisons. Cela tendrait a demontrer que la prise en charge communautaire des delinquants suicidaires ou souffrant de troubles mentaux peut avoir une influence sur la qualite de vie de ces derniers mais aussi, indirectement, sur celle des personnes vivant ou travaillant en milieu carceral.
Les candidoses cutanéo-muqueuses : physiopathologie et conseils à l'officine

Les candidoses cutaneo-muqueuses, issues de la proliferation des levures du genre Candida, doivent etre connues des professionnels de sante en raison des mycoses qu'elles peuvent engendrer, en particulier chez les sujets fragilises. En effet, les levures du genre Candida comptent parmi les dix micro-organismes pathogenes les plus frequemment isoles en mycologie humaine. Les difficultes d'interpretation resident dans le fait que leurs habitats naturels sont principalement les muqueuses et la peau de l'homme. Le passage de l'etat commensal a l'etat pathogene depend de la virulence de l'agent causal, mais surtout des conditions favorisant la multiplication anormalement importante de ces agents potentiellement infectieux. Ce travail s'appuie sur la physiopathologie de Candida albicans, espece majoritairement en cause dans les candidoses cutaneo-muqueuses. Les aspects cliniques, le diagnostic, les traitements mais aussi l'emergence de nouvelles especes et la recrudescence des resistances aux traitements des candidoses cutaneo-muqueuses sont aussi explicites. Des fiches pratiques concernant les localisations les plus frequentes des candidoses cutaneo-muqueuses ont ete redigees a l'intention des professionnels de sante et des patients permettant de cibler les conseils d'hygiene et les traitements les plus appropries.
Towards design of a nailfold capillary microscopy image analysis and diagnosis framework using grid technology

Nailfold capillary microscopy examination has been used since late 1950s as a non-invasive in-vivo technique for diagnosing and monitoring connective tissue disease in adults. Disorders such as Primary Raynaud's phenomenon, progressive systemic sclerosis, and rheumatoid arthritis were detected in more than 80% of adult patients, by analyzing such high resolution images. Internet computing and grid technologies have changed the way we tackle complex scientific problems. Grid computing environments are characterized by interconnecting a number of heterogeneous resources in geographically distributed domains. They enable large-scale aggregation and sharing of computational, data and other resources across institutional boundaries. In this paper, we discuss and develop a framework for nailfold capillary microscope image acquisition and analysis, using computational power provided by grid platforms. In this way, not only useful medical information can be extracted from large amount of history anamneses in an efficient way, with the use of a number of adequate techniques and methods in high performance computing, but also to diagnose abnormal nailfold capillary in far shorter time, to diagnose patient's disease in real-time basis. Based on the results of the classification, analysis of history anamneses are done to discover updated health information possibly hidden in patients' medical records.
Las causas de la violencia intrafamiliar en Medellín

Este articulo indaga por los determinantes socioeconomicos de la violencia en el hogar. Para tal fin se considera que las decisiones microeconomicas tomadas por agentes al interior del hogar, sobre el consumo de ciertos bienes o la imposicion de alternativas sobre decisiones que deben ser colectivas, generan externalidades negativas o deriva en conflictos que se traducen en eventos de violencia intrafamilar. Empiricamente, usando modelos de eleccion discreta, la evidencia sugiere que factores como el consumo de alcohol o el ocio incrementan la probabilidad de eventos de violencia intrafamilar.
Scalable Lightweight Task Management for MIMD Processors

Multiple Instruction Multiple Data (MIMD) processors are becoming increasingly viable for realizing enhanced performance in embedded applications, particularly for compute intensive applications that do not lend themselves to GPUlike (SIMD) processors. Like their SIMD counterparts, MIMD architectures demand careful consideration of software architecture and design. In this paper, we focus on lightweight task management that is typical of many parallel programming solutions such as OpenMP, Cilk, Intel TBB. As a representative MIMD embedded processor, we compare the performance and scalability of multiple designs within the context of a 64-core TILE processor from Tilera Corp. We present experimental data collected from the measurement of performance for user-level cooperative scheduling that we are developing to support parallel programming extensions to C/C++. We analyze the performance of wellunderstood scheduling schemes, such as multi-queue workstealing, as well our own designs that are specifically tailored to the underlying hardware and are also designed to adapt to changing application requirements that often occur at runtime.
Combined Order QRD with PIC Based Signal Detection Method for High Mobility STBC System

The Alamouti transmit diversity scheme assumes that the channel remain constant during the length of the code word period. However, in time selective channel, this assumption does not hold good and leads to inter transmit antenna interferences (ITAI). To combat the ITAI effects, we have analyzed various conventional signal detection methods which include diagonalized maximum likelihood (DML), QR decomposition based maximum likelihood (QRD-ML) and ML. But the QRD-ML method suffers from error floor if the initial signal is not detected correctly and it also has high computational complexity due to the implementation of ML method. Hence, in this paper, we have proposed a low complexity order QRD (OQRD) method which eliminates the error floor by detecting and cancelling the strongest signal before the detection of weakest signal. To further improve the system performance, we have cascaded the OQRD method with parallel interference cancellation (PIC). Simulation results show that our proposed OQRD and OQRD-PIC methods achieve performance close to the optimal ML method.
Vitamina D: nuevos paradigmas

La vitamina D ha pasado de ser solo una vitamina, a ser una importante prohormona con multiples efectos en diferentes tipos de tejidos y en diversos procesos fisiologicos. Su accion no solo esta relacionada con el metabolismo mineral oseo y el equilibrio fosfocalcico, sino tambien con efectos importantes en multiples tipos celulares y en diversos mecanismos tales como secrecion y efecto de la insulina, funcion endotelial, regulacion del sistema renina- angiotensina-aldosterona, control del ciclo celular y apoptosis, autotolerancia inmunologica, y efectividad de la accion del sistema inmune ante las infecciones, entre muchos otros efectos. Por lo tanto, la deficiencia de vitamina D se relaciona no solo con raquitismo y osteomalacia, sino tambien con mayor riesgo de diabetes y de enfermedades cardiovasculares, oncologicas, infecciosas y autoinmunes. La prevalencia de la deficiencia de vitamina D es mas alta de lo que tradicionalmente se ha considerado, inclusive en regiones tropicales donde hay mejor exposicion solar. Esta deficiencia se esta convirtiendo en una situacion epidemica en aumento, aun no bien reconocida, con importantes implicaciones en la salud de la poblacion, puesto que se asocia como factor de riesgo para multiples enfermedades, como las anteriormente mencionadas, que en su conjunto constituyen la mayor carga de morbimortalidad a nivel mundial. Tanto la deficiencia como la insuficiencia de vitamina D, pueden presentarse en Colombia, a pesar de estar en zona torrida, debido a la coexistencia de factores de riesgo como exposicion solar inadecuada, insuficiente ingesta de vitamina D, color oscuro de la piel, poca actividad al aire libre, obesidad, uso de algunos medicamentos y lactancia materna sin suplementacion, entre otros. Por lo tanto, se deben tomar medidas efectivas para evitar y detectar oportunamente esta deficiencia, y de esta manera disminuir el riesgo de las diversas enfermedades que de ella podrian derivars
Effective Content-Based Near-Duplicate Video Detection

In this paper, we investigate the effectiveness of various distance-based similarity measures, including the well-known similarity measure Earth Mover's Distance (EMD), and the recently introduced Independent Minimization for Signatures (IM-Sig) on large-scale signature databases. We conduct experiments on eight different databases comprising near-duplicate video clips generated via various edit tasks. To the best of our knowledge, this is the first work investigating the effectiveness of the IM-Sig and the remainder of distance-based similarity measures on databases comprising near-duplicate video signatures (adaptive-binned representations) generated via numerous video edit tasks. The experimental evaluation points out that the IM-Sig shows very accurate results, either exhibiting the same effective results as the EMD or lying directly beyond the results of the EMD, and outperforming the remainder of the state of the art.
A Carrier-Based Implementation of Virtual Space Vector Modulation for Neutral-Point-Clamped Three-Level Inverter

In this letter, space vector pulse width modulation (SVPWM) and virtual SVPWM (VSVPWM) for the neutral-point-clamped (NPC) three-level inverter (TLI) are reviewed briefly. The relationship between VSVPWM and carrier-based PWM is revealed based on the PWM model of TLI with NP current equation. Then, carrier-based VSVPWM (CB_VSVPWM) is proposed. The CB_VSVPWM is implemented by comparing double modulation waves with a single carrier, and the two modulation waves for each phase are deduced. The CB_VSVPWM can simplify the implementation of VSVPWM to a great extent. Moreover, comparisons between SVPWM and CB_VSVPWM are provided in detail. At last, the simple method proposed in this letter is verified by experiments.