Miracle-dz/UniFAR-FTUs huggingface dataset:
Broiler surface temperature distribution of 42 day old chickens

No Brasil frangos de corte sao normalmente alojados de 1 ate 42 dias, quando sao expostos a procedimentos como: jejum, apanha, colocacao em caixas e transporte ate o abate. Manter a homeostase do corpo e de grande importância para a sobrevivencia de frangos de corte sob ambiente quente, especialmente na 7a semana de crescimento. A perda de calor varia nas partes do corpo e esta relacionada a temperatura do ar e a cobertura de penas. Avaliou-se a distribuicao da temperatura superficial usando o processamento de imagens de câmera termografica infravermelho, para caracterizar a temperatura superficial de frangos de corte de 42 dias de idade, no periodo anterior a apanha para o abate. Os frangos foram alojados de 1 a 42 dias e, antes de serem apanhados e transportados para o abate, foram registradas temperaturas superficiais infravermelho durante o dia. Os resultados dos termogramas das regioes com penas e sem penas foram comparados, durante o 42o dia. Alta correlacao entre regioes sem penas e a temperatura ambiente foi encontrada, mostrando que estas areas respondem rapidamente a alteracoes no ambiente do alojamento. Duas funcoes foram desenvolvidas para predizer a temperatura superficial das regioes com e sem penas, do corpo de frangos com 42 dias, sendo conhecida a temperatura do ar do ambiente.
An NADPH oxidase superoxide-generating system in the rabbit aorta.

Superoxide anion can modulate vascular smooth muscle tone and potentially affect the growth response in vascular disease. The present studies were undertaken to characterize the source of superoxide in rabbit aorta. Rings of aorta (5 mm) were incubated in physiological salt solution (PSS) for 30 min at 37 degrees C in the presence of 10 mM diethyldithiocarbamate (DDC) with or without inhibitors of superoxide-generating systems. Rings were then placed in PSS containing 250 microM lucigenin at 37 degrees C in the presence or absence of inhibitors, and changes in amounts of superoxide were determined by measuring chemiluminescence (units). The inhibitors of xanthine oxidase, oxypurinol (300 microM), and of mitochondrial NADH dehydrogenase, rotenone (50 microM), had no significant effect on superoxide levels. An inhibitor of NADPH oxidase, iodonium thiophen, caused a concentration-dependent inhibition of superoxide anion (12.49 +/- 1.48 vs 5.27 +/- 1.81 and 2.30 +/- 0.36 units, control vs 7 microM and 70 microM iodonium thiopen, respectively). A structurally related iodonium compound, diphenyleneiodonium (20 microM), caused a 78% reduction in basal and DDC-evoked superoxide levels. In the presence or absence of DDC, exogenous administration of NADPH (10 microM-1 mM), but not NADP (1 mM), elicited a concentration-dependent rise in superoxide levels that was inhibited by iodonium thiophen. Particulate fractions of whole aortic tissue exhibited NADPH-dependent superoxide production that was inhibited by 1 microM diphenyleneiodonium. (ABSTRACT TRUNCATED AT 250 WORDS)
Structural Aspects of Salivary Glycoproteins

The protective functions of saliva are attributed, in part, to its serous and mucous glycoproteins. We have studied, as representative molecules, the proline-rich glycoprotein (PRG) from human parotid saliva and the high (MGI ) and low (MG2) molecular weight mucins from submandibular-sublingual saliva. PRG (38.9 kDa) contains 40% carbohydrate consisting of 6 triantennary N-linked units and a single peptide chain of 231 amino acids, 75% of which = PRO+GLY+GLN. PRG's secondary structure is comprised of 70% random coil (naked regions) and 30% β-turns (glycosylated domains). MGI (>103 kDa) contains 15% protein (several disulfide linked subunits), 78% carbohydrate (290 units of 4-16 residues), 7% sulfate, and small amounts of covalently linked fatty acids. MG2 (200-250 kDa) contains 30% protein (single peptide chain), 68% carbohydrate (170 units of 2-7 residues), and 2% sulfate. The major carbohydrate units of MG2 are: NeuAcα2, 3Galβ1, 3GalNAc, Galβ1, 3GalNAc, and Fucα1, 2Galβ1, 3GalNAc. MG1 contains hydrophobic domains, as evidenced by its ability to bind fluorescent hydrophobic probes; MG2 does not. Collectively, the biochemical and biophysical comparisons between MGI and MG2 indicate that these two mucins are structurally different. Several functional properties of MG1, MG2, and PRG have been examined, including their presence in two-hour in vivo enamel pellicle, binding to synthetic hydroxyapatite, lubricating properties, and interactions with oral streptococci. The data presented suggest that these glycoproteins may have multiple functions which are predicated, in part, on their carbohydrate units. The potential significance of the structure-function relationships of these glycoproteins to the oral ecology is discussed.
Modified polyriboinosinic-polyribocytidylic acid complex: induction of serum interferon, fever, and hypotension in rabbits

The purposes of this study were to determine whether the febrile and hypotensive reactions to the administration of polyriboinosinic-polyribocytidylic acid [poly (I)-poly (C)] complexed with poly-L-lysine and carboxymethylcellulose (poly ICLC) (9S) encountered in humans could be duplicated in rabbits, and when such duplication was demonstrated, to ascertain whether these untoward reactions could be avoided by (i) administration of hydrocortisone (HC), (ii) alteration of the route of delivery, or (iii) administration of poly ICLC (4S) an interferon inducer of lower molecular weight. Responses to intravenous poly ICLC (9S) in rabbits reproduced adverse reactions in humans, namely fever and hypotension, and were accompanied by high titers of serum interferon. Continuing investigations showed that (i) intravenous pretreatment of rabbits with HC ameliorated hypotensive responses but markedly diminished interferon induction. When HC was given after poly ICLC (9S), both interferon and hypotension induction were likewise depressed. (ii) Intramuscular or subcutaneous poly ICLC (9S) produced neither high titers of serum interferon nor toxic effects. (iii) Poly ICLC (4S) induced high titers of serum interferon and fever, but no hypotension. Poly ICLC (4S) warrants further study.
A Review of Research on Local Government Debts Based on Government Competition

Unlike most of the literature focusing on the local government debt from the view of tax reform,this paper,based on the theory of government competition,inquiries the local government debt problem from the following four aspects: the provision of public goods,the local government's operation under debt,analysis of government competition and local government under game theory,debt risk prevention. This paper summarized the mechanism of government competition's effect on local government debt and elaborated the influence of from the top "yardstick competition",government's pursuit of financial resources and soft budget constrain on local government debt and looked forward to the future study of local government debt.
Biclustering on gene expression data

Microarray technology is a tool which is essential to observe and monitor the genes in an living organism. Biclustering is a strategy to distinguish qualities that are co-directed under a subset of conditions, however are not really co-controlled crosswise over different conditions. The dataset is in the form of matrix, row matrix represents a set of genes and column matrix represents a set of conditions. Each row in a matrix corresponds to set of genes and each column represents a set of conditions. The goal of this project is to identify groups of genes sharing a common subset of regulatory units. A method is needed to select clusters of genes and conditions simultaneously, finding distinctive clusters with less number of rules generated. Feature selection might be assessed from both the proficiency and adequacy perspectives. While the productivity concerns the time needed to discover a set of components is that the adequacy is identified with the nature of the subset of elements. Hence fast clustering is used to cluster the data into two categories (relevant data, irrelevant data). K-means algorithm is employed to bicluster the data in order to divide the input data into four classes. From the calculation of the maximum and minimum specificity of each class, better accuracy is outperformed.
Fine‐needle aspiration cytology of langerhans' cell histiocytosis (Eosinophilic Granuloma) of Bone in Children

Fine‐needle aspiration (FNA) cytology of three cases of Langerham' cell histiocytosis (eosinophilic granuloma [EG]) of bone in children (mean age–8.3 yr; range 5‐11 yr) is presented. Two patients presented with vertebral lesions and the third had a femoral mass. Cytomorphologic features of EG were seen in all cases, including Langerhans' cell histiocytes having oval to reniform shape nuclei with nuclear grooving and abundant pale cytoplasm. The background showed a polymorphic population of cells including neutrophils, lymphocytes, foamy histiocytes, and osteoclasts. Moderate numbers of eosinophils were seen in two cases, while eosinophils were sparse in the third case. Ancillary imrnunocytochemical (ICC) studies performed on the aspirated material demonstrated positive staining for S‐100 protein (all three cases) and T‐6 antigen (one case). Ultrastructural examination (EM) performed in one case demonstrated characteristic Birbeck granules in the histiocytes. A specific cytologic diagnosis was made in all cases, enabling proper chemotherapy in one case, surgical excision in another and spontaneous resolution in the third case. Our experience demonstrates that FNA cytology can make a definitive diagnosis of EG, especially when coupled with ancillary studies such as ICC and EM on the aspirated material.
Large-scale dynamic simulation of highly constrained strands

A significant challenge in applications of computer animation is the simulation of ropes, cables, and other highly constrained strandlike physical curves. Such scenarios occur frequently, for instance, when a strand wraps around rigid bodies or passes through narrow sheaths. Purely Lagrangian methods designed for less constrained applications such as hair simulation suffer from difficulties in these important cases. To overcome this, we introduce a new framework that combines Lagrangian and Eulerian approaches. The two key contributions are the reduced node, whose degrees of freedom precisely match the constraint, and the Eulerian node, which allows constraint handling that is independent of the initial discretization of the strand. The resulting system generates robust, efficient, and accurate simulations of massively constrained systems of rigid bodies and strands.
Ritonavir-Boosted Lopinavir as Maintenance Monotherapy in HIV-Infected Patients Who Achieved Viral Suppression during a Second-Line Protease Inhibitor–Based Regimen

Eligibility criteria were (1) having previously failed first-line nonnucleoside reverse transcriptase inhibitor–based regimens and (2) having achieved virologic suppression >6 months while receiving a protease inhibitor (PI)-based regimen as second-line treatment. Eligible participants were randomized to receive either (1) ritonavir-boosted lopinavir (LPV/r) monotherapy (n = 29) or (2) LPV/r with optimized background regimens (OBRs; n = 31). Median duration of viral suppression before randomization was 45 months. At week 48, viral suppression during LPV/r monotherapy was 86.2% and did not differ from the suppression achieved with LPV/r with OBRs (87.1%, P = 1.000). However, persistent viremia during LPV/r monotherapy tended to be higher than during LPV/r with OBRs (10.3% versus 3.2%, P = .346). History of viral blip during virologic suppression with second-line PI-based regimen is a predictor of achieving viral suppression at all visits (adjusted relative risk 0.255 [95% confidence interval 0.080-0.821], P = .022). Use of LPV/r monotherapy as maintenance regimen in this study produced persistent viremia that tended to be higher than LPV/r monotherapy with OBRs.
CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative

We investigated the mechanisms of immune tolerance raised by tumors by comparing immunogenic and tolerogenic tumor cell clones isolated from a rat colon carcinoma. When injected into syngeneichosts, the immunogenic REGb cells yield tumors that are rejected, while the tolerogenic PROb cells yield progressive tumors and inhibit the regression of REGb tumors. We show here that PROb tumor volume is correlated with an expansion of CD4+CD25+ regulatory T lymphocytes in lymphoid tissues. These cells delay in vivo the rejection of REGb tumors and inhibit in vitro T cell‐mediated immune responses against REGb cells through a mechanism that requires cell contact between effector and regulatory T cells and involves TGF‐β. While total T cells fromPROb tumor‐bearing rats yield no apparent anti‐tumor immune response, depletion of CD25+ T cells restores this reactivity. A single administration of cyclophosphamide depletes CD4+CD25+ T cells in PROb tumor‐bearing animals, delays the growth of PROb tumors, and cures rats bearing established PROb tumors when followed by an immunotherapy which has no curative effect when administered alone. These results demonstrate the role of CD4+CD25+ regulatory T cells in tumor‐induced immune tolerance and the interest of regulatory T cell depletion to sensitize established tumors to immunotherapy.
A Multilevel Model of Organizational Health Culture and the Effectiveness of Health Promotion

Purpose. Organizational health culture is a health-oriented core characteristic of the organization that is shared by all members. It is effective in regulating health-related behavior for employees and could therefore influence the effectiveness of health promotion efforts among organizations and employees. This study applied a multilevel analysis to verify the effects of organizational health culture on the organizational and individual effectiveness of health promotion. Design. At the organizational level, we investigated the effect of organizational health culture on the organizational effectiveness of health promotion. At the individual level, we adopted a cross-level analysis to determine if organizational health culture affects employee effectiveness through the mediating effect of employee health behavior. Setting. The study setting consisted of the workplaces of various enterprises. Subjects. We selected 54 enterprises in Taiwan and surveyed 20 full-time employees from each organization, for a total sample of 1011 employees. Measures. We developed the Organizational Health Culture Scale to measure employee perceptions and aggregated the individual data to formulate organization-level data. Organizational effectiveness of health promotion included four dimensions: planning effectiveness, production, outcome, and quality, which were measured by scale or objective indicators. The Health Promotion Lifestyle Scale was adopted for the measurement of health behavior. Employee effectiveness was measured subjectively in three dimensions: self-evaluated performance, altruism, and happiness. Analysis. Following the calculation of descriptive statistics, hierarchical linear modeling (HLM) was used to test the multilevel hypotheses. Results. Organizational health culture had a significant effect on the planning effectiveness (β = .356, p < .05) and production (β = .359, p < .05) of health promotion. In addition, results of cross-level moderating effect analysis by HLM demonstrated that the effects of organizational health culture on three dimensions of employee effectiveness were completely mediated by health behavior. Conclusion. The construct connections established in this multilevel model will help in the construction of health promotion theories. The findings remind business executives that organizational health culture and employee health behavior help improve employee effectiveness.
Almost perfect auto-correlation sequences for binary phase-modulated continuous wave radar

We propose the so-called “almost perfect auto-correlation sequences” as ideal spreading codes for binary phase-modulated continuous wave radar systems. After appropriate processing, these codes exhibit a perfect auto-correlation profile with zero sidelobes. This property can be exploited to build extremely high-dynamic range radar systems. Simulation examples show that a pedestrian with a radar cross section of -20 dBsm can be clearly distinguished from a bus of 30 dBsm even when they are only half a meter apart.
Dietary modification of human macular pigment density.

PURPOSE The retinal carotenoids lutein (L) and zeaxanthin (Z) that form the macular pigment (MP) may help to prevent neovascular age-related macular degeneration. The purpose of this study was to determine whether MP density in the retina could be raised by increasing dietary intake of L and Z from foods. METHODS Macular pigment was measured psychophysically for 13 subjects. Serum concentrations of L, Z, and beta-carotene were measured by high-performance liquid chromatography. Eleven subjects modified their usual daily diets by adding 60 g of spinach (10.8 mg L, 0.3 mg Z, 5 mg beta-carotene) and ten also added 150 g of corn (0.3 mg Z, 0.4 mg L); two other subjects were given only corn. Dietary modification lasted up to 15 weeks. RESULTS For the subjects fed spinach or spinach and corn, three types of responses to dietary modification were identified: Eight "retinal responders" had increases in serum L (mean, 33%; SD, 22%) and in MP density (mean, 19%; SD, 11%); two "retinal nonresponders" showed substantial increases in serum L (mean, 31%) but not in MP density (mean, -11%); one "serum and retinal nonresponder" showed no changes in serum L, Z, or beta-carotene and no change in MP density. For the two subjects given only corn, serum L changed little (+11%, -6%), but in one subject serum Z increased (70%) and MP density increased (25%). CONCLUSIONS Increases in MP density were obtained within 4 weeks of dietary modification for most, but not all, subjects. When MP density increased with dietary modification, it remained elevated for at least several months after resuming an unmodified diet. Augmentation of MP for both experimental and clinical investigation appears to be feasible for many persons.
Identification and Characterization of a Novel Class of Extracellular Poly(3-Hydroxybutyrate) Depolymerase from Bacillus sp. Strain NRRL B-14911

ABSTRACT The catalytic, linker, and denatured poly(3-hydroxybutyrate) (dPHB)-binding domains of bacterial extracellular PHB depolymerases (PhaZs) are classified into several different types. We now report a novel class of extracellular PHB depolymerase from Bacillus sp. strain NRRL B-14911. Its catalytic domain belongs to type 1, whereas its putative linker region neither possesses the sequence features of the three known types of linker domains nor exhibits significant amino acid sequence similarity to them. Instead, this putative linker region can be divided into two distinct linker domains of novel types: LD1 and LD2. LD1 shows significant amino acid sequence similarity to certain regions of a large group of PHB depolymerase-unrelated proteins. LD2 and its homologs are present in a small group of PhaZs. The remaining C-terminal portion of this PhaZ can be further divided into two distinct domains: SBD1 and SBD2. Each domain showed strong binding to dPHB, and there is no significant sequence similarity between them. Each domain neither possesses the sequence features of the two known types of dPHB-binding domains nor shows significant amino acid sequence similarity to them. These unique features indicate the presence of two novel and distinct types of dPHB-binding domains. Homologs of these novel domains also are present in the extracellular PhaZ of Bacillus megaterium and the putative extracellular PhaZs of Bacillus pseudofirmus and Bacillus sp. strain SG-1. The Bacillus sp. NRRL B-14911 PhaZ appears to be a representative of a novel class of extracellular PHB depolymerases.
Empirical Study on the Compensation Mechanism about Adoption of Agricultural Cleaner Production Technology:A Case Study on the Survey of Farmers in Eryuan County

A case study was carried out on the survey of farmers in Eryuan County,Dali Bai Autonomous Prefecture in Yunnan Province.Research method is the contingent valuation method(CVM). Some theoretical and practical problems were probed assuming the government would provide compensation to farmers.First analyzed the willingness to accept adoption about three types of agricultural cleaner production technologies(ACPT) including of using special fertilizer,straw returned farmland and construction of septic tanks.Second determinated the two compensation manners accepted by farmers were cash compensation and material compensation.Third estimated the three categories of compensation standard wanted by farmers.Finally investigated the degree of perceived need by farmers about the three types of supporting policies that would be implemented by the government to promote clean technology development.
An Ultra Low Power SoC for 2.4GHz IEEE802.15.4 wireless communications

An ultra-low power (ULP) SoC including an IEEE802.15.4 2.4 GHz transceiver designed in 130 nm CMOS technology is presented. Power consumption was minimized by using a concurrent system and design optimization to avoid the over-specification of blocks. A novel minimum complexity partial correlation algorithm is used in the digital baseband receiver and drains an average of 4802 A (packet PSDU=20 bytes). At 1.2 V, the transceiver drains 5.4 mW and 8.1 mW in RX and TX active modes, respectively, and achieves 1% PER for a -81 dBm input power. For a 250 kbit/s data rate, the transceiver attains an energy efficiency of 21.5 nJ/bit RX and 32.5 nJ/bit TX.
Treatment of pulmonary arterial hypertension.

Pulmonary arterial hypertension, which is characterized by vascular proliferation and remodeling of small pulmonary vessels, leads to a progressive increase in pulmonary vascular resistance and, ultimately, to right ventricular failure and death. Despite recent major improvements in therapy, no current treatments cure this devastating condition. This article discusses recent progress in developing treatments that prolong patients' lives and improve their quality of life.
Periodicity intensity for indicating behaviour shifts from lifelog data

Periodic phenomena or oscillating signals can be found frequently in nature and recent research has observed periodicity appearing in lifelog data, the automatic digital recording of everyday activities. In this paper we are exploring periodicity and intensity of periodicity in big data settings, especially when the data is noisy, unevenly sampled and incomplete. An interesting possibility is to compute the intensity or strength of detected periodicity across the time span of a lifelog to see if it reveals changes in this strength at different times, indicating shifts in underlying behaviour. In this paper we propose several metrics to estimate the intensity of periodicity, longitudinally. Evaluation of these metrics is conducted on simulated high-level activity data generated from a proposed model. We also explore periodicity intensity calculated from two real lifelog datasets using. One is “big” data consists of low-level accelerometer data and another one is high level athletic performance data.
Toward a unified service delivery process for next-generation services

In this paper, a framework for a unified service delivery process is proposed for next-generation services within the context of an end-to-end service delivery architecture (SDA). The framework defines service as a provisionable capability of the SDA that is either a connectivity service, a communication service, or a support service. The platform operator (PO) and the service operator (SO) have separate roles in the service delivery value chain. The customer and end user also have different roles, in receiving services and conducting self-services.