Concise Synthesis of Quinazolines, Quinazolinones, Sulfonimide Salts and Triazoles

-------------------------------------------------------------------------------------------------------------5 List of Figures-------------------------------------------------------------------------------------------------------8 List of Tables--------------------------------------------------------------------------------------------------------9 List of Schemes----------------------------------------------------------------------------------------------------10 Abbreviations------------------------------------------------------------------------------------------------------11 Chapter I. Synthesis of quinazolinone and quinazoline derivatives for DNA repair study 1.Introduction-------------------------------------------------------------------------------------------------------12 2.Results and discussion------------------------------------------------------------------------------------------13 3.Expeimental and characterization data------------------------------------------------------------------------16 4.Conclusions-------------------------------------------------------------------------------------------------------19 5.Reference---------------------------------------------------------------------------------------------------------20 Chapter II. Protecting group-free divergent functionalization of quinazolin-4(3H)-ones 1.Introduction-------------------------------------------------------------------------------------------------------21 2.Results and discussion------------------------------------------------------------------------------------------22 3.Expeimental and characterization data------------------------------------------------------------------------27 4.Conclusions-------------------------------------------------------------------------------------------------------29 5.Reference---------------------------------------------------------------------------------------------------------30 Chapter III. Azide–alkyne cycloaddition using nickel catalysis 1.Introduction-------------------------------------------------------------------------------------------------------31 2.Results and discussion------------------------------------------------------------------------------------------32 3.Expeimental and characterization data------------------------------------------------------------------------37 4.Conclusions-------------------------------------------------------------------------------------------------------41 5.Reference---------------------------------------------------------------------------------------------------------42 Chapter IV. Synthesis of trifluoromethanesulfonylimide-based lithium salts 1.Introduction-------------------------------------------------------------------------------------------------------43 2.Results and discussion------------------------------------------------------------------------------------------44 3.Expeimental and characterization data------------------------------------------------------------------------47 4.Conclusions-------------------------------------------------------------------------------------------------------52 5.Reference---------------------------------------------------------------------------------------------------------52