Miracle-dz/UniFAR-FTUs huggingface dataset:
Micro-Electromechanical impedance control for Electrical Balance Duplexing

—The Electrical Balance Duplexer (EBD) implements a form of self-interference cancellation, and can provide high Tx-Rx isolation whilst allowing simultaneous transmit (Tx) and receive (Rx) trough a single antenna in In-Band Full-Duplex (IBFD) radio transceivers. This paper presents a novel Micro- ElectroMechanical Systems (MEMS) based implementation of the tunable balancing impedance component of the EBD. A prototype MEMS tunable impedance demonstrates excellent tuning range and accuracy, and can operate over wide frequency ranges, balancing the EBD at 800 MHz and 1900 MHz to provide > 40 dB isolation over a 20 MHz bandwidth. However, the MEMS tunable impedance is observed to introduce non-linear distortion into the system. This non-linearity does not signiﬁcantly degrade the Tx error vector magnitude, however it has a substantial detrimental impact on the performance of a second stage of linear active cancellation, which achieved just 16 dB of additional cancellation at a Tx power of 23 dBm.
Intraoperative radiotherapy: review of techniques and results

Intraoperative radiotherapy (IORT) is a technique that involves precise delivery of a large dose of ionising radiation to the tumour or tumour bed during surgery. Direct visualisation of the tumour bed and ability to space out the normal tissues from the tumour bed allows maximisation of the dose to the tumour while minimising the dose to normal tissues. This results in an improved therapeutic ratio with IORT. Although it was introduced in the 1960s, it has seen a resurgence of popularity with the introduction of self-shielding mobile linear accelerators and low-kV IORT devices, which by eliminating the logistical issues of transport of the patient during surgery for radiotherapy or building a shielded operating room, has enabled its wider use in the community. Electrons, low-kV X-rays and HDR brachytherapy are all different methods of IORT in current clinical use. Each method has its own unique set of advantages and disadvantages, its own set of indications where one may be better suited than the other, and each requires a specific kind of expertise. IORT has demonstrated its efficacy in a wide variety of intra-abdominal tumours, recurrent colorectal cancers, recurrent gynaecological cancers, and soft-tissue tumours. Recently, it has emerged as an attractive treatment option for selected, early-stage breast cancer, owing to the ability to complete the entire course of radiotherapy during surgery. IORT has been used in a multitude of roles across these sites, for dose escalation (retroperitoneal sarcoma), EBRT dose de-escalation (paediatric tumours), as sole radiation modality (early breast cancers) and as a re-irradiation modality (recurrent rectal and gynaecological cancers). This article aims to provide a review of the rationale, techniques, and outcomes for IORT across different sites relevant to current clinical practice.
Graph-optimized progressive hybrid greyfield wireless access virtualization

In this paper, we develop a new dynamic utility for wireless access virtualization (WAV) optimization embodying highly-dimensional time-varying multi-criteria metrics (i.e., CAPEX and OPEX costs, QoS or QoE, multi-tier and/or multi-RAT HetNets, etc.) that gauge the best deployment and viability scenarios of cloud (C)-and fog (F)-RANs within legacy networks. Exploiting the powerful tool of graph theory, we devise a progressive greyfield WAV strategy that optimizes our dynamic utility through an efficient combination of C- and F-RANs. This strategy is able to readjust very quickly to any changes in existing or new constraints as they evolve or occur in time, respectively. The resulting optimized hybrid RAN deployment outperforms both the greenfield and the pre-planed greyfield “turnkey” WAV strategies.
Dynamic grasp planning of multifingered robot hands based on asymptotic stability

We describe an approach for planning grasps of multifingered robot hands based on a small vibration model. Using features of the grasp configuration, we analyze asymptotic stability, contact situations, and uniaxial fingertip force constraints for the combined planning of finger posture and finger position, and characterize the generalized mass, damping, and stiffness. Choosing the largest time constant of the vibration model as an optimization criterion for planning finger postures and positions, the original problem of dynamic grasp planning is formulated as a nonlinear program. Simulation examples for a three-fingered robot hand grasping a spherical object demonstrate the effectiveness of the approach.
Cabin fever

There remains no financial obstacle to rapid and effective syndromic treatment of STIs in developing countries Prompt treatment of sexually transmitted infections (STIs) with effective antibiotic regimens, preferably contained in a single, supervised dose, is a cornerstone of STI control. The World Health Organization (WHO) revised its treatment guidelines in 2001.1 A variety of regimens is proposed, from which national control programmes are encouraged to choose, depending on the susceptibility of local strains of Neisseria gonorrhoeae and Haemophilus ducreyi , and on the resources available to pay for treatment. WHO treatment guidelines reflect a tension between, on the one hand, the need to recommend the most effective single dose treatment and, on the other, the fact that this may not be available in many developing countries, especially in sub-Saharan Africa. Third generation cephalosporins, for example, have until recently been prohibitively expensive and, for that reason, are not included in the essential drugs list of some African countries. WHO guidelines have therefore included cheaper alternatives for the treatment of gonorrhoea, such as a 3 day course of co-trimoxazole, which are likely to be very much less efficacious. However, essential drug lists should respond to changing circumstances, and new drugs should be added when this is thought to be cost effective by groups of experts. The price of many drugs has fallen dramatically in sub-Saharan Africa in recent years as a result of the development of a large generic drug industry in developing countries, such as India and China, and a vigorous campaign by WHO and NGOs, such as Medecins sans Frontieres (MSF), for better accessibility to essential drugs. Current prices and sources of a number of anti-infective drugs have been …
Magnetic Resonance Imaging of the Idiopathic Inflammatory Myopathies

Idiopathic inflammatory myopathies are chronic diseases clinically characterized by symmetrical proximal muscle weakness. MRI has assumed a major role in the evaluation and management of these conditions. It is sensitive to the presence of inflammation and edema, especially with incorporation of fat suppression sequences, so it is a useful tool for establishing an early diagnosis, for evaluating the extent and number of lesions, and for determining the right site for biopsy. The noninvasive nature of the procedure makes it ideal for serial studies to evaluate response to treatment. Whole‐body MRI can scan a large volume of muscles without prolonged acquisition time and has the potential to identify previously unsuspected sites of involvement. MRI is also an excellent technique for identifying areas of fatty infiltration within the muscles, which usually occurs in the late stages of inflammatory myopathies. In summary, MRI has revolutionized the way muscular diseases are diagnosed and treated.
Parameter estimation of two-mass mechanical loads in electric drives

This paper presents a method for parameter estimation of two-mass mechanical loads. A discrete-time polynomial model with an output error (OE) structure is used in parameter estimation. Four different identification setups are obtained when open-loop estimation and various possibilities of choosing the input and output signals in closed-loop estimation are considered. All four setups are analyzed, and the identifiabilities are compared. It is discovered that all four identification setups can be used to obtain reasonable parameter estimates.
Acoustics of historic spaces as a form of intangible cultural heritage

Archaeological interest in the study of the acoustics of important historic buildings is currently gaining in importance, and there are several areas where research is conducted. Among these I include music archaeology, archaeology of sound, archaeomusicology and archaeoacoustics (Watson & Keating 1999; Scarre & Lawson 2006; Knight 2010: 1). Research on acoustic space can, in principle, be divided into two types of project: the measurement of acoustic parameters and the storage of acoustics as audio heritage.
Successful Renal Transplantation in a Patient with Behcet Disease and Hodgkin Lymphoma in Remission

Behcet’s disease (BD) is an inflammatory multisystemic disease characterized by perivascular inflammation and generally presents with recurrent oral and genital ulcers and uveitis. It is known that BD may also involve the kidneys. Amyloidosis, glomerulonephritis (crescentic, proliferative), IgA nephropathy, interstitial nephritis are commonly described renal lesions which may lead to end-stage renal disease (ESRD) in BD. Immunosuppressive therapies used for the treatment of BD may cause malignant diseases (lymphoma, skin and solid organ malignancies, etc). The risk with azathioprin is especially high after 10 years of treatment. Cyclosporine, another immunosuppressive agent frequently used for treatment of BD, also has tumorigenic potential and is associated with renal toxicity and renal failure. Renal transplantation may be performed in patients with malignancies after a 2-5 year complete remission period, although it may differ according to the type of tumor. We report a case of end-stage renal disease and Hodgkin’s lymphoma occurring after treatment with immunosuppressive medicine for BD. The patient was successfully treated with renal transplantation.
A Joint Distribution Approach for Audio Signal Discrimination

The purpose of audio signal discrimination is needed to build two different libraries: speech library and music library, from a stream of sounds. The classification algorithms of audio signal can be divided into three categories: time-domain, frequency-domain, and time-frequency domain approaches. The first two approaches were discussed thoroughly in literature. Since audio signals are considered nonstationary, in general, these two approaches may fail in reflecting the behavior of each signal correctly. Therefore, in this paper, a joint distribution approach, the evolutionary spectrum (ES), is introduced and proposed for the discrimination purpose. To show the effectiveness of the proposed method, some comparison examples with classical methods is done
Lipid map of the mammalian cell

Technological developments, especially in mass spectrometry and bioinformatics, have revealed that living cells contain thousands rather than dozens of different lipids [for classification and nomenclature, see Fahy et al. (Fahy et al., 2009)]. Now, the resulting questions are what is the relevance of each of these unique molecules for the cell and how do cells use lipids for their vital functions? The answer requires an integrative approach – cellular lipidomics – which addresses first the distribution of all lipids between the various organelle membranes and then their local organization within each membrane. To understand lipid homeostasis and its dynamics, one has to study the localized metabolism of lipids, their transport within and between the various membranes, and the sensors and effectors that govern these processes. In terms of function, above all, we need to understand the physical behavior of complex lipid mixtures and their effect on local protein structure, organization and function. Finally, in the course of evolution, many lipids and lipid metabolites have acquired key functions in the signaling networks that wire the cell, by binding to cognate receptors and by recruiting proteins to specific membranes. The accompanying poster describes the lipid content of the various organelle membranes, illustrates lipid localization and dynamics in various subcellular locations, and explains the structure of lipids and their biosynthetic pathways. Below, we highlight additional issues that are important in lipid cell biology, and aim to provide a framework and a timely update for lipid systems biology.
On Combining RDF Streams and Remotely Stored Background Data

To perform complex tasks, continuous queries in RDF Stream Processing can combine RDF streams and quasi-static background data, as depicted in Figure 1. While the former is pushed in the query engine, the latter is pulled from the repository. In the following, we focus on the cases where background data is stored remotely and can be accessed through the SERVICE clause. That means, background data are retrieved from SPARQL endpoints, or from Web APIs through OBDA techniques. Existing engines usually retrieve the background data at each new iteration. But as soon as the background data volume increases, the cost to retrieve them increases as well, and consequently engines are at the risk of becoming unresponsive. For example, the C-SPARQL engine delegates the evaluation of the SPARQL operators to the ARQ engine: SERVICE clauses are managed through sequences of invocations to the remote endpoints. In this way, they generate high loads on remote services and suffer from slow response time.
Some questions regarding the understanding and prediction of turbulent flow

Recent progress and remaining challenges related to the understanding and prediction of turbulent flow are described. This is done by explaining the need for the development and basic features of unified turbulence models which integrate, recover and extend well known existing computational methods for turbulent flow calculations. The availability of unified turbulence models enables a significant progress with regard to both our understanding of basic mechanisms of turbulence and efficient and accurate numerical predictions of turbulent flows. However, the development of a complete mathematical theory of the stochastic integro-differential equations involved still represents a significant
Finanzkrise und Lebenszufriedenheit

Die Lebenszufriedenheit der Osterreicher ist bisher durch die Finanzkrise (fast) nicht beeintrachtigt worden. Das bedeutet nicht, dass man die Krise hierzulande ignoriert: Die Einschatzung der internationalen Wirtschaftslage durch die Osterreicher und ihre Erwartungen reagierten sehr wohl auf auslandische Schocks. Allerdings schlugen diese blos abgeschwacht auf die Einschatzung der nationalen Arbeitsmarktlage und praktisch nicht auf die personliche Betroffenheit durch, weder in Bezug auf den eigenen Arbeitsplatz noch auf die eigene Finanzlage. Die Stabilitat der Einschatzungen von Lebenszufriedenheit und personlicher Lage beruht vermutlich auf der geringen Arbeitslosigkeit, der Absicherung durch das Sozialsystem sowie dem Vertrauen der Osterreicher in die Regierung und deren Beschaftigungspolitik. Einkommenserwartungen und Systemvertrauen sind bisher nicht erschuttert worden, und die Gefahren einer Erosion des Sozialsystems durch die Globalisierung werden hierzulande offenbar als weniger bedrohlich angesehen als im Ausland.
Trend estimation of blood glucose level fluctuations based on data mining

We have fabricated calorie-calculating software that calculates and records the total calorific food intake by choosing a meal menu selected using a computer mouse. The purpose of this software was to simplify data collection throughout a person’s normal life, even if they were inexperienced computer operators. Three portable commercial devices have also been prepared a blood glucose monitor, a metabolic rate monitor and a mobile-computer, and linked into the calorie-calculating software. Time-course changes of the blood glucose level, metabolic rate and food intake were measured using these devices during a 3 month period. Based on the data collected in this study we could predict blood glucose levels of the next morning (FBG) by modeling using data mining. Although a large error rate was found for predicting the absolute value, conditions could be found that improved the accuracy of the predicting trends in blood glucose level fluctuations by up to 90 %. However, in order to further improve the accuracy of estimation it was necessary to obtain further details about the patients’ life style or to optimise the input variables that were dependent on each patient rather than collecting data over longer periods.
Medication administration errors from a nursing viewpoint: a formal consensus of definition and scenarios using a Delphi technique.

AIMS AND OBJECTIVES To develop and achieve formal consensus on a definition of medication administration errors and scenarios that should or should not be considered as medication administration errors in hospitalised patient settings. BACKGROUND Medication administration errors occur frequently in hospitalised patient settings. Currently, there is no formal consensus on a definition of medication administration errors or scenarios that should or should not be considered as medication administration errors. DESIGN This was a descriptive study using Delphi technique. METHODS A panel of experts (n = 50) recruited from major hospitals, nursing schools and universities in Palestine took part in the study. Three Delphi rounds were followed to achieve consensus on a proposed definition of medication administration errors and a series of 61 scenarios representing potential medication administration error situations formulated into a questionnaire. RESULTS In the first Delphi round, key contact nurses' views on medication administration errors were explored. In the second Delphi round, consensus was achieved to accept the proposed definition of medication administration errors and to include 36 (59%) scenarios and exclude 1 (1·6%) as medication administration errors. In the third Delphi round, consensus was achieved to consider further 14 (23%) and exclude 2 (3·3%) as medication administration errors while the remaining eight (13·1%) were considered equivocal. Of the 61 scenarios included in the Delphi process, experts decided to include 50 scenarios as medication administration errors, exclude three scenarios and include or exclude eight scenarios depending on the individual clinical situation. CONCLUSION Consensus on a definition and scenarios representing medication administration errors can be achieved using formal consensus techniques. RELEVANCE TO CLINICAL PRACTICE Researchers should be aware that using different definitions of medication administration errors, inclusion or exclusion of medication administration error situations could significantly affect the rate of medication administration errors reported in their studies. Consensual definitions and medication administration error situations can be used in future epidemiology studies investigating medication administration errors in hospitalised patient settings which may permit and promote direct comparisons of different studies.
Osteoporosis, Mineral Metabolism and Arthritis

Bone gives the potency and hardness of the skeleton in addition to play an important role in the storage of calcium and other mineral salts. It has a rich blood supply, contains connective tissue of cells in a fibrous organic matrix soaked in inorganic bone salts [1]. Bone is reported to be negatively feigned by several diseases as well as the therapy itself such as rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis and spondyloarthritides, and osteoarthritis [2]. The clinical importance of the bone is still not fully defined as most patients do not examined for bone densitometry in routine orthopedic work. This review focuses on the problem of osteoporosis and mineral metabolism in relation to different arthritis conditions. We must take in consideration that greater understanding of this problem will increase the health care level and rheumatic patients live.
Inconsistent data repairs in database integrations

In the operations of multiple database integrations, one of the most prominent data quality problems is the existence of inconsistencies. Due to independence of data management among different information sources, there exist several possibilities for repairs of integrated data. In order to get good repairs and preserve the correct data, this paper introduces a new algorithm for repairing inconsistent data among multiple tables based on functional dependencies, which keeps integrity of source databases without deletions of tuples. The algorithm determines the tuples that are potentially updated by analyzing related attribute statistic measures, and is of objective, accurate and effective properties. A repairing system structure is presented, and some comparisons with other related work are given at last.
A molecular mechanism for sensory adaptation based on ligand-induced receptor modification.

Physiological responses mediated by cell-surface receptors frequently adapt or "desensitize" (i.e., terminate despite persistent occupancy of receptors by ligand). Binding of ligands to the external domains of a wide variety of surface receptors induces covalent modification of their cytoplasmic domains. A mechanism is presented in which the variety of receptor states generated by ligand binding and covalent modification act together to regulate physiological responsiveness. The development of the model is guided by observations of adaptation for chemotaxis in Escherichia coli and adenylate cyclase activation in Dictyostelium. The general features of the marked response and eventual exact adaptation predicted by the model match those observed in the experimental systems.
In vitro studies of the substrate specificities of heparan sulfate 2-O- and 6-O-sulfotransferases.

The signaling of various molecules involved in development and regulation of cell growth are regulated by heparan sulfate (HS). Specific binding of HS to ligand proteins depends on the HS sulfation pattern, where the spacing and number of O-sulfate groups are of special importance. HS 2-O-sulfotransferase catalyzes 2-O-sulfation of glucuronic and iduronic acid residues with a 5-fold higher preference for iduronic acid, as inferred from previously determined kinetic parameters. To study in more detail the regulation of HS hexuronic acid 2-O-sulfation, we tested the ability of the enzyme to catalyze glucuronic acid 2-O-sulfation in polysaccharide mixtures with different glucuronic acid/iduronic acid ratios, using 3'-phosphoadenosine 5'-phospho[S-35]sulfate as sulfate donor. The 2-O-sulfotransferase revealed a more pronounced preference for 2-O-sulfation of iduronic acid than predicted. Even incubations with a 99:1 ratio of glucuronic acid to iduronic acid resulted in almost exclusive iduronic acid 2-O-sulfation. Unexpectedly, when the 2-O-sulfotransferase was co-immunoprecipitated with the glucuronyl C5-epimerase (that converts glucuronic acid to iduronic acid), both glucuronic acid and iduronic acid residues were sulfated to the same extent when a polysaccharide containing only glucuronic acid was used as a substrate. Attempting to understand the mechanism by which extended regions of iduronic acid 2-O-sulfation are formed during HS biosynthesis, a H-3-labeled N-sulfated iduronic acid containing octasaccharide substrate was incubated with the 2-O-sulfotransferase and 3'-phosphoadenosine 5'-phosphosulfate. The 2-O-sulfotransferase showed a preference for mono-2-O-sulfated substrates as compared with octasaccharides with no 2-O-sulfate group.