Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Music Therapy for Pain and Anxiety versus Literature on the Immediate and Future Perceptions of Cardiac Patients

This study investigated the effects of music therapy on pain, anxiety and present and future psychosocial perceptions of cardiac patients. Forty-eight men and women admitted to cardiac progressive care unit of a local regional medical center served as subjects for the study. Subjects were assigned to one of three groups. Sixteen subjects received relaxation and imagery paired with live music, sixteen subjects received literature, and sixteen subjects received no intervention. Pre- and Post intervention data included pain medication intake and a self-report questionnaire concerning pain, anxiety, and present and future psychosocial perceptions. Patients in the music group were given a relaxation tape, which involved relaxation exercises and imagery, paired with music. Patients were called one week after discharge and given the questionnaire once more. Patients were also asked about their pain medication intake. Results from the study were collected and analyzed. The results revealed the music group scored significantly lower on the pre posttest questionnaire involving pain, anxiety and present and future perceptions. A difference was found in the groups(cid:146) pre/post medication intake but results were not significant. The analysis found that the music group had significantly lower scores on the questionnaire one-week post discharge. The music group also had a significantly lower level of pain medication one-week post discharge. It was concluded that music therapy interventions are beneficial to subjects in a post-operative setting.
Instabile Angina pectoris

Zusammenfassung In den letzten Jahren wurden bei der instabilen Angina pectoris sowohl im Bereich des pathophysiologischen Verständnisses, der Risikostratifizierung als auch der Therapie große Fortschritte unternommen. Nebst besserer klinischer Risikostratifizierung stehen uns heute ebenfalls biochemische Marker wie z.B. das Troponin zur initialen Risikoabschätzung zur Verfügung. Zusätzlich zur Standardtherapie mit Azetylsalizylsäure und der intravenösen Vollheparinisierung verfügen wir über neuere Medikamente wie die niedermolekularen Heparine sowie die GPIIb/IIIa-Rezeptorantagonisten, welche in größeren Studien mit oder ohne koronare Intervention ihre Wirksamkeit bewiesen haben, vorerst jedoch vor allem den Hochrisikopatienten vorbehalten sein sollten. Die interventionelle Therapie wurde insbesondere durch die Entwicklung von koronaren Stents verbessert, die Wahl des richtigen Zeitpunkts der Intervention bleibt jedoch kontrovers.
Sistema de Medição e Análise de Qualidade de Redes Celulares Móveis

This article presents a crowdsourcing system developed to measure parameters of cellular networks through user’s smartphones, using an application based on Android Operating System and on a remote server platform to run calculations and aggregate the obtained data. Due to the difficulty of mapping issues in cellular networks, the proposed system aims to be an online and transparent tool for users and operators in order to help not only the customer to choose their service provider, but also to provide useful analyzes to operators that may contribute to the improvement of cellular coverage. Palavras-Chave— Android, Cobertura de Redes Celulares Móveis , Crowdsourcing, Big-data. Keywords— Android, Mobile Cellular Network Coverage , Crowdsourcing, Big-data.
Classificação do óleo de algodão em processo de semirrefino usando técnicas de processamento de imagem

The present article presents a classification model of steps in the process of semi refining of cotton oil by image processing. A simple system of efficient analysis was obtained, allowing its use on the factory floor, thus assisting in the process as to the assertiveness in the desired semi-refined state and its quality control. Two different pattern recognition algorithms were used: K-Nearest Neighbor and Quadratic Discriminant Analysis, with validation of the Leave-one-out strategy. Both algorithms achieved hit rates of more than 90%, with QDA being the best result with more than 94% accuracy. Keywords— Oil Classification, Cotton Oil, Image Processing, KNN, QDA, Matrix of Confusion, Leave-one-out.
Relación entre vitamina A y alteraciones mucocutáneas y pilosas en niños de zonas palúdicas

Objective: to know the class and frequency of skin, mucous membranes and hair alterations in children of endemic malaria zones of Antioquia (Colombia). Methodology: non-blind balanced experimental design. Ninety three children with malaria were included and followed up during 30 days. Results: 61% of these children had chronic or global or both kinds of malnutrition, according to the anthropometric indexes. Before treatment there were alterations in the following proportions: skin 41%, labial mucous membrane 12%, oral mucous membrane 2%, tongue 15% and hair 16%. At day 30 there had been improvement in all these sites, except for the skin (alterations: 42%). Plasmatic retinol level was lower than 20 i g/dL in 56% of patients at day 1 (with malaria) and in 4.5% at day 30 (without malaria). During follow-up retinol levels ( i g/dL) were as follows: 19.1 ± 6.8 at day 1; 32.6 ± 7.4 at day 8; 31.2 ± 7.9 at day 30. In general, the state of the skin, labial and oral mucous membranes, tongue, and hair was not associated with retinol level either at day 1 or at day 30; the only exception was the state of the hair at day 30: 50% of those with retinol level lower than 20 i g/dL had non-healthy hair, as compared with only 9% of those with retinol level at 20 i g/dL or higher; such state was also not associated with malnutrition risk, except for the association of abnormal skin with chronic and global malnutrition: 60% of children with abnormal skin had chronic and global malnutrition; the corresponding figure for those with normal skin was 20%. Conclusions: skin, mucous membranes and hair alterations were very frequent in these children of endemic malaria zones of Antioquia, who also had a high prevalence of chronic, global or both kinds of malnutrition (61%) and low frequency of deficiency of plasmatic retinol (4.5%). In general, skin, mucous membranes, and hair alterations were not associated with either retinol levels or nutritional state.
Evaluating the quality of reverse engineered object-oriented designs

Software quality is a multifaceted concept that can be described from different perspectives. Five perspectives are the transcendental view, user view, manufacturing view, product view, and value-based view. The definition of software quality is based upon the perspective taken. However, these views do not address the design phase of the software lifecycle. Moreover, the issues pertinent to forward engineering do not necessarily parallel those pertinent to reverse engineering. The quality of a forward engineered design can be discussed in several contexts, such as how well the design represents the requirements specification or the evaluation of the design using a given set of metrics. In reverse engineering, however, this is not the case. The issues involved in evaluating the quality of an object-oriented design extracted from an imperative language differ from those involved in evaluating a forward engineered object-oriented design. This paper discusses the shortcomings of measuring the quality of a reverse engineered object-oriented design using current models based on forward engineering, and offers insights to a plausible solution.
Constantino: Uma Arquitetura BFT Escalável e Eficiente para Blockchains

Devido ao grande interesse em bitcoins e aplicações de blockchain, as aplicações distribuídas com requisitos de segurança e de tolerância a faltas bizantinas têm recebido uma atenção adicional. Algoritmos como Prova de Trabalho (PoW) e Prova de Estaca (PoS) foram desenvolvidos para lidar com a consistência, capturando aspectos de sistemas abertos (openess). No entanto, ao escalarem bem com o número de réplicas considerável, a maioria destes sistemas baseados no PoW ou no PoS não oferecem desempenho como as abordagens mais convencionais que tratam com a consistência de réplicas. Algoritmos como o PBFT que são baseados em replicação ativa podem se ajustarem a blockchain, garantindo um desempenho melhor na consistência das réplicas. Assim, abordagens híbridas como Tendermint ou Hot Stuff foram desenvolvidas oferecendo openess e desempenho. Embora atinjam grandes números de réplicas, estas soluções dependem dos algoritmos PoW ou do PoS o que torna caro o consenso entre suas réplicas. Projetos como o Hyperledger propõe blockchains de alto desempenho onde o consenso tradicional do PBFT é usado sem a necessidade do PoW ou do PoS. No entanto, algoritmos de PBFT, no consenso de suas réplicas, não escalam bem devido aos custos quadráticos (O(n 2 )). Assim, na literatura, estruturas hierárquicas foram propostas com o PBFT para lidar com o crescente número de réplicas. Nós, neste trabalho, propomos uma arquitetura hierárquica com um algoritmo de PBFT para lidar com o modelo altamente adversário do ambiente blockchain. Nossa solução apresenta um consenso com custo linear em relação ao número de réplicas.
Bioethics in Japan, 1980-2009: Importation, Development, and the Future

This article introduces the history of modern bioethics in Japan from its emergence in the early 1980s, and follows its trajectory into the present. This article supplements a previously published brief historical review of the 1980–2000 period and suggests that the history of bioethics in Japan can best be understood as occurring in two phases: Importation (1980–1999) and Development (2000–2009). In a field only thirty years old, it is still too early for a purely academic study based on historical archives. This essay therefore reflects the author’s subjective views of the history as a witness to many of the debates of both periods. Looking forward, I hope to see a “Phase III”, the post-2009 future of bioethics in Japan.
Current directions in the treatment of early stage Hodgkin's lymphoma

Radiation therapy (RT) alone and the combined modalities therapies (CMT) of chemotherapy and RT for early stage Hodgkin lymphoma have achieved excellent results for early stage Hodgkin lymphoma for over thirty years. A major concern has been the late toxicities of treatment most of which are attributable to the RT. Recently several studies have suggested that chemotherapy alone is a reasonable treatment option for patients with early stage non-bulky Hodgkin lymphoma. At the present time this does not seem to be appropriate for patients with early stage bulky disease (mediastinal mass > 1/3rd the thoracic diameter or peripheral nodal mass > 10 cm, since RT to regions of tumor bulk in combination with chemotherapy has been demonstrated to reduce the risk of recurrence.
The prognostic significance of sentinel lymph node biopsy in malignant melanoma

The sentinel lymph node technique renders the regional tumour stage determination possible. In malignant melanoma this technique helps select those patients for whom the performance of regional block dissection is justified. The tumour involvement of the regional lymph nodes is one of the most important prognostic factors, not directly dependent on the parameters of the primary tumour. Considering the controversial prognostic significance of spontaneous regression of the primary tumours and the uncertainty in determining the tumour thickness, we think that the result of the sentinel lymph node biopsy is a step forward in settling the problem. S-100 protein and circulating tumour cells are important markers of the progression. In theory, they may predict a positive sentinel lymph node, but the related information available in the literature is rather infrequent. In period of November 1997 to June 2005, we performed sentinel lymph node biopsy with the double labelling technique on 450 patients, with following results: the successful rate 99.4%, the sentinel lymph node positivity 15.5%, the false negative rate 14.8% The independent predictors of the sentinel lymph node status the Breslow thickness and the ulceration of the primary tumour have been found, in harmony with the literary data. S-100 concentration was measured by the luminescence immunoassay with 301 patients. The sentinel node negative and positive groups did not differ from each other concerning the average values (p=0.18). The percentage difference was also minimal. Thus the serum S-100 concentrations do not predict the presence of micrometastasis in sentinel nodes. 269 patients with sentinel lymph node biopsy have been selected for histological analysis regarding the intermediate regressing signs of the primary tumour. Signs of intermediate regression were detected by histology in 27.9% of the patients. Regressive tumours were localized predominantly on the trunk (p=0.006), were significantly thinner (p=0.00001) and less frequently ulcerated (p=0.003) than tumours without regression. Moreover, the majority of regressive melanomas were of the superficial spreading type (p=0.00001) and their sentinel node status was more favourable (p=0.026). By multivariate analysis, however, the Breslow thickness and ulceration of the primary tumour were
OML: Review of model formulation

OML is a local-scale operational air pollution model for estimating dispersion from point sources and area sources. Based on the original OML model, several model versions have been developed over the years to treat different regulatory aspects in Denmark, including assessment of industrial air pollution, regulation of odour and assessment of ammonia deposition. The model was reviewed in 2005-06, and model performance was evaluated with more experimental data than previously. A number of problems were identified, and various issues have been resolved with introduction of new parameterisations in certain parts of the model. The outcome of the process is a revised model, referred to as the "Research Version" of OML.
Validation of disease recordings in Swedish dairy cattle

This thesis examines the completeness of the Swedish dairy disease recording system: it attempts to quantify how much disease the system’s database captures relative to what farmers find and veterinarians treat. Two field studies were conducted. In the first, 177 farmers recorded information about disease events, regardless of whether the disease event had resulted in a veterinary visit. In the second, farm copies of veterinary records (851 records from 112 herds) were collected. The proportion of disease events receiving veterinary treatment was estimated, and measures of disease incidence based on the farmers’ data were compared with incidences estimated from the Dairy Disease Database (ddd). Further, the completeness of the ddd was estimated based on agreement between information in the ddd and farmer-reporting and herd-copies, respectively. Differential completeness was also evaluated. Finally, the probability of a successfully registered disease event for the whole disease recording process was estimated for five different disease complexes, based on the results of both field studies. The overall completeness of veterinary treated disease events in the ddd was estimated to be 71% and 75%, based on the farmers’ recordings and on the farm copies, respectively. Differential completeness linked to regions, veterinary employment type and between different groups of animals was found. The probability of a successfully registered disease event (regardless of veterinary treatment) in the ddd varied between 30% for diarrhoea and 72% for puerperal paresis. Whether or not the farmer contacted a veterinarian was found to be the most influential step in the recording process, followed by whether or not the disease record was registered in the raw data file at the Swedish Dairy Association. Lack of completeness in the ddd will result in conservative disease incidence measures. Underreporting of veterinary treated disease events, as well as undercoverage of farmer-observed events, was found to vary depending on several factors which could introduce bias in estimates based on the ddd, which primarily is a problem if the data are used for epidemiologic research and less so for other areas.
DDS-induced colorectal fibrosis in mice: anti-fibrotic effects of GED 0507-34 levo, a novel PPARγ ligand

Intestinal fibrosis is a progressive process characterized by de novo synthesis and uncontrolled deposition of extracellular matrix components (ECM) following a tissue chronic inflammation mainly regulated by Transforming Growth Factor (TGF)β/ Smads pathway. Frequently associated to Inflammatory Bowel Disease (IBD), intestinal fibrosis may lead to stenosis and obstructions that require surgery up to 75% of patients as drugs currently used in IBD are unable to improve fibrostenosis lesions (1). Peroxisome proliferator-activated receptor (PPAR)-γ is able to antagonize (TGF) β/Smads and could be an crucial target to develop novel antifibrotic therapeutic strategies (2). Aim of this study is to evaluate the antifibrotic action of a novel PPARγ agonist, GED 0507-34 levo, in colonic fibrosis in mice. Immunohistochemistry and immunoblotting evaluations, TGFβ1, CTGF, Collagen types I-III, Smad3, α-SMA, were performed in in three groups of C57BL/6 mice: Dextran Sulphate Sodium (DSS) colitis group, DSS+GED group and controls. Evident macroscopic and microscopic lesions in the most of colons of DSS treated mice were observed compared to DSS+GED mice and controls. The tissue levels of the main markers of fibrosis resulted significantly increased in DSS mice and restored by administration of GED. GED seems to prevents ECM colonic deposition and to improve the intestinal fibrotic lesions by its ability in controlling TGFβ/Smads pathway signalling activation.
ORIGINAL RESEARCH—HISTORY: Nikolaj A. Bogoraz (1874–1952): Pioneer of Phalloplasty and Penile Implant Surgery

Phalloplasty and penile implants are outstanding pioneering procedures introduced in 1936 by the Russian surgeon Nikolaj A. Bogoraz and are thus of eminent interest to the urological and plastic surgeon. This article from the history of medicine will discuss his biography and scientific achievements during the first half of the 20th century.
Le retour de la conception biomédicale du paludisme dans les institutions internationales

We argue here that efforts against malaria are in line with a biomedical conception of the disease, which departs from the comprehensive and positive definition of health established at Alma-Ata in 1978. The use of community health workers and the use of rapid diagnostic tests illustrate this phenomenon. International institutions should consider malaria as the expression of a social, economic and environmental vulnerability rather than a parasitic infection that has to be eliminated.
Betere criteria voor inclusie in het zorgtraject chronische nierinsufficiëntie: een kritische noot

Chronische nierinsufficientie is een chronische pathologie die mede door de vergrijzing erg vaak voorkomt. Het door het RIZIV ingevoerde zorgtraject chronische nierinsufficientie heeft als doel een kader te bieden voor de complexe zorg voor deze patienten. Hoewel het invoeren van dit zorgtraject heel wat voordelen biedt, stellen wij ons in dit artikel vragen bij de huidige inclusiecriteria voor dit zorgtraject. Deze criteria zijn immers maar beperkt wetenschappelijk onder- bouwd en zeer veel ouderen komen in aanmerking. We stellen alternatieve criteria voor gebaseerd op longitudinale studies. De parameters gebruikt in deze criteria zijn: de geschatte glomerulairefiltratiesnelheid (eGFR), de leeftijd van de patient, de aan- of afwezigheid van proteinurie, de aanwezigheid van verwikkelingen van nierlijden en de evolutie van al deze parameters in de tijd
Teachers' evaluation of formative assessment on summative assessment in undergraduate medical education

Background : Assessment is important in all forms of learning. Formative assessments have evolved as a means to adapt to student needs. Summative assessment designed to make judgments about students' performance and produce grades Formative assessment is the assessment that takes place during a course or programming of study whereas summative assessment is normally carried out at or towards the end of a course. Objective: To determine the teachers' view about the influence of formative assessment on the result of summative assessment in undergraduate medical course. Method: This cross sectional descriptive study was carried out from July 2009 to June 2010 over 106 teachers of selected two government and two private medical colleges. A structured and pretested questionnaire included different opinion about the influence of formative assessment on summative assessment was distributed among respondents and data were collected for analysis. Results: This study revealed that majority of the teachers (77%) considered feedback from formative assessment to students is important to close up the learning gap. Eighty two percent teachers were in agreement that through formative assessment teachers identified students' weak point and 69% supported that formative assessment motivates the students for deep learning and regular study. However, frequent formative assessment hampers students' independent learning which produces negative effects in summative exam. Conclusion: Formative assessment has got significant effect on summative assessment in various aspects. DOI: http://dx.doi. org/10.3329/bjme.v3i1. 18591 Bangladesh Journal of Medical Education Vol.3(1) 2012: 18-21
PDE -5 inhibitors’ implications in women: Are they of help?

Introduction: Introduction of the oral phosphodiesterase isoenzyme-5 inhibitors (PDE5-Is) has revolutionized sexual medicine by affording effective treatment for erectile dysfunction. PDE5 hydrolyses cyclic GMP specifically to 5′-GMP. Since its launching, PDE5-Is have stimulated scientific interest for their impending benefits in various implications for the welfare of the human beings. Aim: To highlight the possible potential implications of PDE5-Is in women.Participants and methods: A systematic review was carried out till June 2017 based on a search of concerned articles in Medline, medical subject heading databases, Scopus, The Cochrane Library, Embase, and CINAHL databases without language restriction. Keywords used to assess that outcome and concerned associations were PDE5 inhibitors, sildenafil, tadalafil, vardenafil, avanafil, women, and females.Main outcome measures: Different implications for PDE5-Is in women.Results: Oral PDE5-Is have beneficial medical implications in women. Sexual implications include female sexual dysfunction, female sexual arousal disorder, antidepressant-associated sexual dysfunction, and affected relationship. Gynecological implications include endometrial thickness, abortion, preeclampsia, fetal growth restriction, clitoral engorgement, primary dysmenorrhea, uterine blood flow, oligohydramnios, poor ovarian response, ovarian ischemia/reperfusion, and uterine contractility. Urological implications include overactive bladder and interstitial cystitis, whereas dermatological implications include systemic sclerosis and cellulite. In addition, PDE5-Is proved to be beneficial in pulmonary arterial hypertension, coronary dysfunction, esophageal motility, and some metabolic effects.Conclusion: Oral PDE5-Is are an eye-catching therapeutic class of agents with beneficial effects for women, which could be potentially applied after well-designed clinical trials.