Miracle-dz/UniFAR-FTUs huggingface dataset:
Combination of Text Mining and Corrective Neural Network in Short-term Load Forecasting

Short-term load forecasting refers to short period load prediction of utility ranging from one hour to several days ahead. It is meaningful in planning and dispatching the load to meet the electricity system demand. The inaccuracy load forecasting can increase the electricity operating costs. In this paper, a novel method is presented and discussed which combines text mining and corrective neural network (TM-CNN) methods. Subsequently, a numeric example of daily maximum load forecasting is used to illustrate the performance of TM-CNN method, and the experiment results also reveal that TM-CNN method outperforms the autoregressive moving average(ARMA) and BP Artificial Neural Network(BPNN) approaches.
Editorial: dynamic changes of the inflammation‐based index predict mortality following chemoembolisation for hepatocellular carcinoma

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[Efficiency and safety of thrombus aspiration plus intra-infarct-related artery administration of tirofiban during primary angioplasty].

OBJECTIVE To investigate whether thrombus aspiration plus intra-infarct-related artery bolus administration of tirofiban via the aspiration catheter is superior to thrombus aspiration alone in improving myocardial perfusion in patients with ST-elevation myocardial infarction (STEMI) undergoing primary angioplasty. METHODS In this single center retrospective study, 108 patients with STEMI who underwent angioplasty after thrombus aspiration plus intra-infarction related artery 500 µg tirofiban administration, with subsequent 12-hour intravenous infusion of 0.1 µg×kg(-1)×min(-1) after angioplasty (thrombus aspiration + tirofiban group) and 108 matched control patients with STEMI who underwent angioplasty after thrombus aspiration (thrombus aspiration group). The primary end points included thrombolysis in myocardial infarction (TIMI) flow immediately after angioplasty, complete ST-segment elevation resolution (> 70%) at 90 minutes after angioplasty and the peak of creatine kinase-MB (CK-MB) and troponin I (TnI). The secondary end points were the left ventricular ejection fraction (LVEF) in the hospital and at 9 months follow-up as well as major adverse cardiac events (MACE: cardiac death, target vessel revascularization, re-infarction) at 9 months and any bleeding events. RESULTS Baseline characteristics of the two groups were well-balanced. The TIMI 3 flow rate (97.22% vs. 87.04%, P = 0.011) and the complete ST-segment resolution rate (66.67% vs. 50.91%, χ(2) = 6.129, P = 0.047)were significantly higher in the thrombus aspiration + tirofiban group than in the thrombus aspiration group. The peak of CK-MB (83.9 U/L vs. 126.1 U/L, P = 0.034) and TnI (42.7 ng/ml vs. 72.5 ng/ml, P = 0.029) were significantly lower in the thrombus aspiration + tirofiban group than in the thrombus aspiration group. LVEF in the hospital favored thrombus aspiration + tirofiban the group (45.7% ± 10.8%, 42.9% ± 9.9%, t = 1.99, P = 0.049). There was a tendency to decreased MACE rate at 9-month follow-up, which favored thrombus aspiration + tirofiban the group (logrank χ(2) = 2.865, P = 0.09). Bleeding events were similar between the two groups. CONCLUSION Thrombus aspiration plus intra-infarct-related artery bolus administration of tirofiban in patients with STEMI undergoing primary angioplasty may improve myocardium perfusion, attenuate myocardial ischemia and result in a better clinical prognosis compared to thrombus aspiration alone.
A datapath generator for full-custom macros of iterative logic arrays

A new flexible datapath generator which allows the automated design of full-custom macros covering dedicated filter structures as well as programmable DSP cores is presented. The underlying concept combines the advantages of full-custom designs concerning power dissipation, silicon area, and throughput rate with a moderate design effort. In addition, the datapath generator can be easily included in existing semi-custom design flows. This enables highly efficient VLSI implementations of optimized full-custom macros (datapaths) embedded into synthesized standard cell designs covering uncritical structures in terms of area, power, and throughput (e.g. control paths) using common design flows. In order to demonstrate the datapath generator assisted design flow, the implementation of a time-shared correlator is presented as an example.
Lessons learned from gene expression profiling of cutaneous T‐cell lymphoma

Gene expression studies of cutaneous T‐cell lymphoma (CTCL) span a decade, yet the pathogenesis is poorly understood and diagnosis remains a challenge. This review examines the varied approaches to gene expression analysis of CTCL, with emphasis on cell populations, control selection and expression data collection. Despite discordant results, several dysregulated genes have been identified across multiple studies, including PLS3, KIR3DL2, TWIST1 and STAT4. Here, we provide an overview of the most consistently expressed genes across different studies and bring them together through common pathways biologically relevant to CTCL. Four pathways – evasion of activation‐induced cell death, T helper 2 lymphocyte differentiation, transforming growth factor‐β receptor expression, and tumour necrosis factor receptor ligands – appear to encompass the most frequently affected genes, hypothetically providing insight into the disease pathogenesis.
Fabrication of nanofibers with antimicrobial functionality used as filters: protection against bacterial contaminants

A comparative study of antimicrobial activity is done using three different electrospun nanofibers namely—CA, PAN, and PVC used as control and with various amounts of AgNO3 being treated with UV‐irradiation leading to the enhancement of silver nanoparticles. DMF is used as the common solvent which helps to undergo spontaneous slow reduction at room temperature to form silver nanoparticles followed by UV‐irradiation using a 400 W source. The time required for the formation of silver nanoparticles is short and they are more or less well dispersed with few such aggregates. The presence of silver nanoparticles is confirmed using various characterization techniques. The antimicrobial activity is studied using nanofibers with fabricated functionality. Biotechnol. Bioneg. 2007;97: 1357–1365. © 2007 Wiley Periodicals, Inc.
Agrin Is a Heparan Sulfate Proteoglycan (*)

In the present study we have identified the extracellular matrix protein agrin as a major heparan sulfate proteoglycan (HSPG) in embryonic chick brain. Using monoclonal antibodies and a polyclonal antiserum to the core protein of a previously identified HSPG from embryonic chick brain, our expression screened a random-primed E9 chick brain cDNA library. Twelve cDNAs were isolated that were shown to be identical to the chick extracellular matrix protein agrin. Western blot analysis and immunocytochemistry confirmed that agrin is a HSPG that is identical with the HSPG from embryonic chick brain. A polyclonal antiserum to recombinant agrin protein recognized agrin as a diffuse band of over 400 kDa in extracts from brain and vitreous humor. The agrin immunoreactivity on the blot was shifted to a defined band of approximately 250 kDa after treatment of the samples with heparitinase or nitrous acid, and this banding pattern was indistinguishable from immunoreactivity obtained with antibodies to the brain HSPG. We also show that agrin binds tightly to anion exchange beads, indicating that the molecule is highly negatively charged, which is a hallmark of all proteoglycans. Furthermore, the agrin antiserum recognizes the affinity purified HSPG from chick brain and vitreous humor. Immunocytochemistry demonstrated that agrin is expressed in developing brain, and is especially abundant in developing axonal tracts, in a distribution identical to the staining of the brain HSPG with monoclonal antibodies. We also show that the anti-HSPG antibodies stain the synaptic site of the neuromuscular junction, in agreement with agrin expression. Thus, our studies demonstrate that chick agrin is a HSPG that is prominent in the embryonic chick brain. Since previous studies from our laboratories have shown that this proteoglycan interacts with neural cell adhesion molecule, our studies raise the interesting possibility that neural cell adhesion molecule and agrin are interactive partners that may regulate a variety of cell adhesion processes during neural development, including synaptogenesis.
Success and Failure

This paper examines the dynamics in organizational innovation processes, and in particular, the role blockages. The case covers the process of designing a joint-stock enterprise that is partly owned by the employees and partly by the federation of municipalities, and is to deliver primary health care services to a set of municipalities. After a promising start, the process is now stuck before it has reached the implementation phase. The purpose of the paper is to examine the dynamics in the organizational innovation process, and in particular, the role of blockages and failures. By highlighting the value of complexity theoretical thinking, this paper seeks to contribute to our understanding of the nature of organizational innovation in the public sector and the analytical power of complexity. The data consists of interviews with the key actors in the process and is analysed by applying theory driven content analysis. Preliminary results suggest that the organizational innovation process is characterized by an active use of relational potential and a sequence of unexpected events resulting in emergent patterns. The space of possibilities not only frames the system but also enables co-evolutionary dynamics to emerge. Contrary to the fitness (or performance) landscape models, where the (organizational) structure is seen as an important determinant of the innovation potential, it does not seem to play a central role in this particular case. Results suggest that the innovation itself emerges in the complex responsive processes of relating between key actors, long before the end result of the process is realized. A structural failure might turn into a relational success.
Effects of mepartricin, a polyene macrolide antibiotic, on estrogen-induced hyperplastic growth of the dorsolateral prostate and seminal vesicle in immature castrated rats

Objective. To investigate the effects of mepartricin, a polyene macrolide antibiotic, on estrogen-induced hyperplastic prostate and seminal vesicle (SV) growth in castrated rats. Material and methods. Immature rats aged 3 weeks were castrated and left untreated for 1 week. Then, 17β-estradiol benzoate (E2-BA) was subcutaneously injected at a dose of 10 µg/day twice weekly, and mepartricin was orally administered at doses of 2.5, 5 and 10 mg/kg once daily for 3 weeks. The weights and hydroxyproline contents of the prostate and SV, the activity of growth factors (GFs) in the dorsolateral prostate (DLP) and the serum estrogen level were measured. Histological examination of the prostate and SV was also performed. Results. Mepartricin dose-dependently suppressed the increase in the serum estrogen level, the weights and hydroxyproline contents of the DLP and SV and the elevation of GF activity in the DLP induced by E2-BA treatment. Histological examination also revealed that treatment with mepartricin reduced collagen accumulation and thickening of the smooth muscle layer in the DLP and SV, and proliferation of the glandular epithelium in the DLP. Conclusions. These results suggest that mepartricin suppresses hyperplastic growth of the DLP and SV induced by estrogen in immature castrated rats, the underlying mechanism being a reduction in the serum estrogen level, thereby suppressing stromal cell proliferation and activation.
Construction of an In Vivo Nonsense Readthrough Assay System and Functional Analysis of Ribosomal Proteins S12, S4, and S5 in Bacillus subtilis

ABSTRACT To investigate the function of ribosomal proteins and translational factors in Bacillus subtilis, we developed an in vivo assay system to measure the level of nonsense readthrough by utilizing the LacZ-LacI system. Using the in vivo nonsense readthrough assay system which we developed, together with an in vitro poly(U)-directed cell-free translation assay system, we compared the processibility and translational accuracy of mutant ribosomes with those of the wild-type ribosome. Like Escherichia coli mutants, most S12 mutants exhibited lower frequencies of both UGA readthrough and missense error; the only exception was a mutant (in which Lys-56 was changed to Arg) which exhibited a threefold-higher frequency of readthrough than the wild-type strain. We also isolated several ribosomal ambiguity (ram) mutants from an S12 mutant. These ram mutants and the S12 mutant mentioned above (in which Lys-56 was changed to Arg) exhibited higher UGA readthrough levels. Thus, the mutation which altered Lys-56 to Arg resulted in aram phenotype in B. subtilis. The efficacy of our in vivo nonsense readthrough assay system was demonstrated in our investigation of the function of ribosomal proteins and translational factors.
Fine‐needle aspiration biopsy diagnosis of extrarenal malignant rhabdoid tumor

Two cases of extrarenal malignant rhabdoid tumors are presented in which diagnosis was suggested by fine‐needle aspiration biopsy and confirmed by histologic and electron microscopic examination. Fine‐needle aspiration smears in both cases revealed round to polygonal cells with vesicular nuclei and prominent nucleoli. Several tumor cells contained cytoplasmic inclusions composed of intermediate filaments. A majority of the tumor cells stained strongly for vimentin and cytokeratin. Electron microscopic examination revealed many cells with large aggregates of intermediate filaments corresponding to the cytoplasmic inclusions. Fine‐needle aspiration biopsy may be used for diagnosing malignant rhabdoid tumor. The diagnosis may be further confirmed by immunohistochemistry and electron microscopy. Diagn Cytopathol 1994;11:271–276. © 1994 Wiley‐Liss, Inc.
Estimating Anthropometry with Microsoft Kinect

Anthropometric measurement data can be used to design a variety of devices and processes with which humans will interact; however, collecting these data is a very time-consuming process. In order to facilitate the rapid and accurate collection of anthropometric data, a novel system is under development which makes use of multiple Microsoft Kinect sensors to estimate body sizes. The Kinect is an appealing sensor for this application because it can be purchased for around 250 dollars, can be quickly set up in many different environments, and can easily be interfaced with a Windows computer. This paper will present the experimental setup and procedure used as well as some preliminary results.
Simplified algorithm of 3D-SVPWM in three level 3-phase 4-wire active power filter

3D-SVPWM algorithm is used for synthesizing the desired bridge output voltage and generating compensation currents to cancel the harmonics. In this paper, depict the detail step for calculate the command vector and duty cycle of each leg in three level 3-phase 4-wire shunt active power filter system. After induction, proposed a simplified 3D-SVPWM algorithm. Compare to the traditional 3D-SVPWM algorithm, the proposed SVPWM algorithm simplified the operation, and shorten calculating time. Simulation and experimental results validate the correctness and feasibility of proposed algorithm.
Age‐Related Bidirectional Changes in Neuropeptide Y Peptides in Rat Adrenal Glands, Brain, and Blood

Abstract: Age‐related changes in neuropeptide Y (NPY) regulation were studied in rat adrenal glands, brains, and blood by radioimmunoassay and biochemical characterization using reversed phase HPLC and gel filtration chromatography. NPY immunoreactivity (pmol/g tissue ± SEM) in rat adrenal glands increased from 7 ± 1 (6 weeks old) to 1,500 ± 580 (69 weeks old). Biochemical characterization by HPLC showed that this increase was due to those of NPY and methionine sulfoxide NPY. In contrast, in rat brain, NPY content decreased in an age‐dependent manner specifically in striatum, hippocampus, medulla oblongata, and spinal cord and the sulfoxide form was not detected. In rat blood, the circulating level of NPY was high (3–5 pmol/ml plasma ± SEM) but did not change significantly with age or by adrenal demedullation. Only a small increase of the sulfoxide form of NPY was observed in aged rat plasma. The age‐dependent changes in regulation and modification of NPY in adrenal glands and in specific brain areas may have physiological relevance in the regulation of catecholamine release from adrenal glands and some brain functions during aging.
Autophagy Gene Disruption Reveals a Non-vacuolar Cell Death Pathway in Dictyostelium*

Types of cell death include apoptosis, necrosis, and autophagic cell death. The latter can be defined as death of cells containing autophagosomes, autophagic bodies, and/or vacuoles. Are autophagy and vacuolization causes, consequences, or side effects in cell death with autophagy? Would control of autophagy suffice to control this type of cell death? We disrupted the atg1 autophagy gene in Dictyostelium discoideum, a genetically tractable model for developmental autophagic vacuolar cell death. The procedure that induced autophagy, vacuolization, and death in wild-type cells led in atg1 mutant cells to impaired autophagy and to no vacuolization, demonstrating that atg1 is required for vacuolization. Unexpectedly, however, cell death still took place, with a non-vacuolar and centrally condensed morphology. Thus, a cell death mechanism that does not require vacuolization can operate in this cell death model showing conspicuous vacuolization. The revelation of non-vacuolar cell death in this protist by autophagy gene disruption is reminiscent of caspase inhibition revealing necrotic cell death in animal cells. Thus, hidden alternative cell death pathways may be found across kingdoms and for diverse types of cell death.
Psychiatric Disorders and Labor Market Outcomes: Evidence from the National Latino and Asian American Study

This paper investigates to what extent psychiatric disorders and mental distress affect labor market outcomes in two rapidly growing populations that have not been studied to date-ethnic minorities of Latino and Asian descent, most of whom are immigrants. Using data from the National Latino and Asian American Study (NLAAS), we examine the labor market effects of meeting diagnostic criteria for any psychiatric disorder in the past 12 months as well as the effects of psychiatric distress in the past year. The labor market outcomes analyzed are current employment status, the number of weeks worked in the past year among those who are employed, and having at least one work absence in the past month among those who are employed. Among Latinos, psychiatric disorders and mental distress are associated with detrimental effects on employment and absenteeism, similar to effects found in previous analyses of mostly white, American born populations. Among Asians, we find more mixed evidence that psychiatric disorders and mental distress detract from labor market outcomes. Our findings suggest that reducing disparities and expanding access to effective treatment may have significant labor market benefits-not just for majority populations, as has been demonstrated, but also for Asians and Latinos.