Miracle-dz/UniFAR-FTUs huggingface dataset:
Osteopenia Leading to Dystrophy of Alveolar Ridges at Persons Suffering from Hypothyroidism

The paper presents the study of features of parodentium microhaemodynamics via laser doppler flowmetry at patients with osteopenia caused by hypothyroidism. The study covered patients of 30–57 years old, among which there were 35 women and 20 men. Adequate hormonal therapy was carried out in the main group. Comparison with the control group where patients refused hormonal therapy was made. The integrated blood flow indicator, blood flow intensity, indicators of active and passive blood flow regulation, level of oxygenation of tissues was defined. The dental status was estimated. Blood test to assess the level of calcium, thyreotrophin-releasing hormone was made. It is defined that the hygienic indexes in the main group are better than in the control one. In the main group the oxygenation level of parodentium tissues is also higher. The resorption of jaw osseous structure in the control group is more expressed. At assessment of CFE index showed considerable number of extracted teeth in the control group. Biochemical indicators in the control group are less stable, which is expressed by considerable distribution of the calcium level in blood of the control group. The study showed that adequate hormonal therapy at hypothyroidism allows considerably reducing changes of jaw osseous structure and ensuring successful prosthetics of oral cavity.
Database design and implementation for a digestive tract diagnostics support system

The article briefly presents the process of diagnosing gastrointestinal diseases and discusses existing techniques of supporting it with automatic analysis of video from gastrointestinal examinations. Further, the process of designing a specialized medical database is described. The main goal of the created database is to provide data for the training of automatic classifiers of gastrointestinal diseases. Finally, the collected data and acquired results are presented.
Profitable Bayesian implementation in one-shot mechanism settings

In the mechanism design theory, a designer would like to implement a desired social choice function which specifies her favorite outcome for each possible profile of all agents’ types. Traditionally, the designer may be in a dilemma in the sense that even if she is not satisfied with some outcome with low profit, she has to announce it because she must obey the mechanism designed by herself. In this paper, we investigate a case where the designer can induce each agent to adjust his type in a one-shot mechanism. We propose that for a profitable Bayesian implementable social choice function, the designer may escape from the above-mentioned dilemma by spending the optimal adjustment cost and obtain a higher profit. Finally, we construct an example to show that the designer can breakthrough the limit of expected profit which she can obtain at most in the traditional optimal auction model.
The Impacts of Enterprise Management Accounting Lack on Internal Control

Internal accounting control system is the basis of normal operation of enterprises. All management work of an enterprise should begin with the establishment and improvement of its internal control system. All decision-making of an enterprise should be governed by a sound internal control system, and all activities of the enterprise should not be free from outside. Internal accounting control system is the core of the overall framework of enterprise internal control. It is a control system formulated and implemented to improve the quality of accounting information, protect the safety and integrity of assets, and ensure the implementation of laws, regulations and regulations.
The Impact of Supportive Housing for Homeless People with Severe Mental Illness on the Utilization of the Public Health, Corrections, and Emergency Shelter Systems: The New York-New York Initiative

This article assesses the impact of public investment in supportive housing for homeless persons with severe mental disabilities. Data on 4,679 people placed in such housing in New York City between 1989 and 1997 were merged with data on the utilization of public shelters, public and private hospitals, and correctional facilities. A series of matched controls who were homeless but not placed in housing were similarly tracked. Regression results reveal that persons placed in supportive housing experience marked reductions in shelter use, hospitalizations, length of stay per hospitalization, and time incarcerated. Before placement, homeless people with severe mental illness used about $40,449 per person per year in services (1999 dollars). Placement was associated with a reduction in services use of $16,282 per housing unit per year. Annual unit costs are estimated at $17,277, for a net cost of $995 per unit per year over the first two years.
HbE β-Thalassaemia in Malaysia: revisited

HbE β – thalassaemia is a public health problem in Malaysia and the most common type of thalassaemia seen in the Malaysia. It shows considerable diverse phenotypes. Complete molecular analysis to identify primary/ secondary alleles of thalassaemia and gene modifiers are arbitrary predictors of possible outcome of disease. Early diagnosis is important. Patients need to be classified as minor, moderate (TI) and severe. Clinical diagnosis requires carefulobservations over a period of time with good record keeping of growth, sexual maturation and quality of life. Patients with haemoglobin (Hb) levels less than 7 gm/dl should be treated as transfusion dependent β-thalassaemia major to prevent complications that occur progressively with advancing age. Hb levels less than 7 gm/dl show patients are destined to be short, have splenomegaly and skeletal abnormalities. Pre transfusion mean Hb levels kept between 9-10 gm/dl by transfusion will suppress bone marrow activity and decrease iron absorption through gastrointestinal tract.
Ketorolac tromethamine 0.4% as a treatment for allergic conjuctivitis

Background: Acular LS (ketorolac tromethamine 0.4%) ophthalmic solution, a reformulation of the original Acular (ketorolac tromethamine 0.5%), is indicated for the reduction of ocular pain and burning/stinging following corneal refractive surgery. Objective: This manuscript will review the off-label application of this topical NSAID medication as a treatment for allergic conjunctivitis. Methods: An extensive MedLine search was undertaken to evaluate data on the use of ketorolac for allergic conjunctivitis. Data on both human and animal data were reviewed. Results/conclusions: Studies have demonstrated that ketorolac 0.4% has equivalent efficacy to ketorolac 0.5%. Several studies have demonstrated that ketorolac effectively treats allergic conjunctivitis. Ketorolac 0.4% is effective when used as either monotherapy or as adjunct therapy to steroids.
OTT_A_219562 8637..8644

Aiyun Liu 1 Jiutao Qiao Liyuan He Zhangmeng Liu Jing Chen 1 Fenghua Pei Yaju Du 1Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University, Harbin, People’s Republic of China; 2Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, People’s Republic of China Background: Colorectal cancer (CRC) is one of the most common malignant tumors in the world. Our previous study revealed that nitrogen permease regulator-like-2 (NPRL2), a promising anti-tumor gene, was downregulated at both the blood and tissue levels in CRC patients compared with that in healthy individuals. Purpose: This study aims to explore the role of NPRL2 in CRC. Methods: Herein, we constructed NPRL2 overexpression lentivirus vectors and transfected them into HT29 cells. The transfected cells were inoculated subcutaneously into nude mice. Tumor growth, pathology, apoptosis, and the protein expression of caspase-3, caspase-7, Bax, Bcl-2, and phosphorylated protein kinase B (p-Akt) were evaluated. To further explore whether NPRL2 could reduce drug resistance of CRC cells against oxaliplatin (L-OHP) and 5-fluorouracil (5-FU), we constructed a tumor model using HT29 cells. The tumor model was treated with lentiviral particles assembled with vectors encoding NPRL2 and exposed to L-OHP and 5-FU. Tumor growth, pathology, apoptosis, and the protein expression of caspase-3, caspase-7, Bax, Bcl-2, p-Akt, P-glycoprotein (P-gp), and multidrug resistance protein 1 (MRP1) were evaluated. Results: The results indicated that in the in vivo CRC xenograft model, NPRL2 reduced the tumor volume and weight and enhanced apoptosis. Our results also confirmed that NPRL2 enhanced the sensitivity of CRC cells to L-OHP and 5-FU. Our studies further demonstrated that NPRL2 exerted anti-tumor and anti-drug resistance effects through the caspase-3, caspase-7, Bax, Bcl-2, Akt, P-gp, and MRP1 pathways. Conclusion: Our present work demonstrated that NPRL2 exhibited anti-tumor effects and enhanced the sensitivities of CRC cells to L-OHP and 5-FU through the P-gp andMRP1 pathways.
Modal Logics of Truth and Falsity

2. In our poor, postmodern, time quite a lot of people, including, unfortunately, a few logicians and many philosophers, are following rather Nietzsche than Frege trying to dissolve, at least in human beings’ minds, this border together with other natural borders. They like to be happy on wanton vacation without any border, including the border between Truth and Falsity and the border between real and unreal. Are guardians still doing they job? Do logicians fulfill their duty?
The Size and Determinants of Unpaid Work - the Gender Comparison

Examination of unpaid work is inter alia essential for the assessment of gender differences in different countries. The paper compares the various aspects of unpaid work between genders. We can confirm that women spent more time by unpaid work in all countries in the sample. The difference is more often evident in less developed countries. The main aim of the paper is to identify the determinants of unpaid work done by men and women. Using the regression models applied on cross-sectional data, we found that the determinants are different for the two genders. On the one hand the unpaid work done by women is more influenced by the number of children and elderly in the population as well as by the wage level in the labour market. On the other hand, male unpaid work is affected mostly by the number of Internet users and the educational level. The size of paid work is an important determinant for both genders.
GP and NPC1 Targeted Herbal Compound – An in Silico Evidence for Ebola Drugs

In silico based drug design is one of the potential techniques to discover new drug leads against essential drug targets. Ebola viruses (EBOV) of Filo viruses, consists of five species, viz. Zaire, Sudan, Ivory Coast, Bundibugyo, and Ravn, spreading hemorrhagic fatal fever worldwide. The reservoirs are yet to be confirmed, but the fruit bats have been considered to be the possible hosts for the serious transmissions. EBOV pathogenesis depends on viral recognition, attachment and transmission of virion to host cell and lysis. Recent research reveals that apart its own proteins (to be named, NP, VP35, VP40, glycoprotein (GP), sGP, VP30, VP24, and RNA-dependent RNA polymerase (L)), the EBOV use Niemann-Pick C1 for the transmission. In this study, a preliminary assessment of the natural compounds (from Ayurvedic plants) based on bioavailability related criteria, were docked with potential drug targets of Ebola virus. Out of the seventeen leads, six (neoandrographalide, fumaric acid, vasicoline, andrographalide and andrograpanine) showed prominent binding to active sites of GPs and NPC1s proteins. These drugs bind to the residues responsible for native conformation of the viral proteins (GPs and NPC1s). Since, the natural compounds show minimal side-effects compared to the synthetic ones, the use of these compounds or formulations possessing them through a proper delivery platform or as leads for future drugs will upgrade the mode of Ebola treatment.
THE EFFECT OF ND12FE77CO5B6 POWDER ELECTROLESS BIENCAPSULATION METHOD ON ATMOSPHERIC CORROSION OF POLYMER BONDED MAGNETIC MATERIAL

s In study the effect of the of Nd-(Fe,Co)-B particles biencapsulation method on bonded magnetic material atmospheric corrosion behavior has been evaluated. Bonded magnets were prepared from Nd12Fe77Co5B6 magnetic powder after biencaspsulation. In this work three kind of biencapsulation method (double layer coating of powder particles) were applied. The powder biencapsulations with bilayers of NiP/epoxy resin, phosphate/epoxy resin and Cu/epoxy resin, was carried out to protect the surface of the powder particles against oxidation during manufacturing process. In the paper the results of accelerated gravimetric tests were carried out in so called artificial industrial atmospheres. Experimental conditions of the chosen environments were as follows: aerosol produced from aqueous solution of 3 mg/dm3 SO2, at temperature of 40 °C. The corrosion rates were determined on the basis of sample’s mass gain per surface unit in order to relationship of Δm/S versus time. It has been established that used method of magnetic powder pretreatment satisfactory encapsulates individual particles of the powder and consequently, significantly inhibits corrosion processes of the final material in artificial industrial atmospheres but only in case when used coating layer tightly cover entire particle surface (Ni-P/epoxy resin and phosphate/epoxy resin). There is no improvement in the case of use the encapsulation with Cu/epoxy resin, because the Cu layer does not cover entire surface of powder surface.
Combustion and Emission Characteristics of Water Hyacinth Based Composite Briquettes

Biomass has been used in the last few decades as energy source to mitigate greenhouse gas emission during production and utilization. However, majority of biomass are bulky, uneven and have low energy density and therefore not suitable to be utilized as fuel without an appropriate process. The study was conducted to evaluate combustion and emission characteristics of composite water hyacinth briquette as an alternative source of energy. Water hyacinth was chopped using a shredder and left for two weeks in a heap to partially decompose. The material was thoroughly mixed manually with dried and crushed charcoal dust and cow dung in the ratios as done by Okia et al of water hyacinth,2016: charcoal dust: cow dung of 100:0:0 (control), 80:10:10, 70:20:10, 70:10:20, 60:30:10, 60:20:20 and 60:10:30 (by weight). The resulting material was then mixed into soupy slurry in water. Simple prototype briquetting mold was fabricated to facilitate densification of these residues into hollow cylindrical briquette at a pressure of 1MPa. The experimental results revealed that the mixture that gives optimal combustion characteristics was 60:30:10. Water hyacinth alone (100:00:00) gave the best emission characteristics having 28.51ppm carbon monoxide and 452.80ppm carbon dioxide though ranking third with 13,623 μg/m in particulate matter. This study demonstrates that composite water hyacinth briquettes have good combustion and emission characteristics therefore can be utilized as alternative source of energy.
Building Alignment Between Pre-college and First-Year Engineering Programs

how to matriculation of engineering the Abstract - Developments in pre-college engineering such as the incorporation of engineering in the Next Generation Science Standards and the rapid growth of formal and informal pre-college engineering programs and activities has resulted in increasing numbers of students arriving in first-year engineering programs with significant prior engineering experience. To assist first-year engineering faculty and staff with improving the alignment of their programs with their students’ precollege engineering experiences, in the first part of this workshop we present a framework we developed to understand how pre-college engineering programs and activities influence students’ transitions into first-year engineering programs. Supported by both qualitative and quantitative data, we will describe ways that precollege engineering activities can both support and hinder this transition. For the second part of this workshop, we will work with the participants to identify and share ways that they recognize elements of this framework in their own first-year engineering programs, brainstorm and share strategies for promoting successful transitions from pre-college to first-year engineering, and ways to differentiate instruction to address the wide range of pre-college engineering experiences represented in the first-year engineering classroom. This workshop presents a means for participants to begin a larger conversation related to understanding the impact of pre-college engineering participation on the first-year engineering experience, and ways that first-year engineering programs can adapt to address the changing conceptions of and experience with engineering of incoming students.
Distribución de catalizadores en el reactor de hidrotratamiento de des- tilados medios, vı́a optimización multiobjetivo

The regulations established in recent years about sulfur content in diesel, motivated studyng catalyzers in middle distillate hidrotreating reactors, in terms of design and distribution, by developing a deterministic Mixed Integer Nonlinear Programming model. An optimal configuration of catalyzer’s bed for each objective to be met was obtained with this model. However the posibility of satisfying the objectives simultaneously leads us to define a multiobjective model which minimizes the cost of reactor design, the amount of aromatic sulfur and the amount of monoaromatic; and maximizing the production of nafthenes. In order to obtain efficient solutions, the ε Augmented Constraints method inplemented in GAMS was used, leading us to Pareto optimal solutions, which represent optimal configurations about design and catalytic bed, from where the desition maker can choose any of them, taking into account their inmediate needs.
The IFLYTEK System for Blizzard Challenge 2017

This paper introduces the IFLYTEK speech synthesis system for Blizzard Challenge 2017. The task is to build a speech synthesis system on a 6.5-hour children’s audio book corpus. The submitted system followed our previous one proposed in Blizzard Challenge 2016. A hidden Markov model (HMM)-based unit selection system was built with improvements in both the front-end text processing and back-end acoustic modeling. In the front-end, long short term memory(LSTM)-based recurrent neural networks(RNN) were adopted for tone and breaking indices (ToBI) prediction. In the back-end, another LSTM-RNN based acoustic model was built and the hidden layer was adopted as context embedding feature for unit selection. Evaluation results demonstrated that our system performed good on all aspects of paragraph test, which proved the effectiveness of our proposed system.
Supplement of Quantifying the contributions of riverine vs. oceanic nitrogen to hypoxia in the East China Sea

panels c, d) during summer (June to August, ‘JJA’; panels a, c) and winter (December to February, ‘DJF’; panels b, d) 2008–2013. The main branch of the Kuroshio is well reproduced, visible as a band of high current velocities in the surface and subsurface (Figs. S1a, b). Maximum velocities of 20 up to 1.6ms−1 occur during summer in the surface layers directly east of Taiwan (Fig. S1a). North of Taiwan, summer currents are driven mainly by inflow through Taiwan Strait, indicated by the band of relatively high velocities off the Chinese coast (Figs. S1a, b). At about 27.5 ◦N, 122.5 ◦E, the cur25
Data Farming und simulationsbasierte Robustheitsanalyse für Fertigungssysteme

Diskrete Simulation ist eine etablierte Methodik zur Untersuchung des dynamischen Verhaltens von komplexen Fertigungsund Logistiksystemen. Konventionelle Simulationsstudien fokussieren auf einzelne Modellaspekte und spezifische Analysefragen. Der Umfang der ausgeführten Szenarien ist häufig gering. Das Konzept des DataFarming verwendet das Simulationsmodell als Datengenerator für eine breite Skale von Experimenten und ermöglicht unter Nutzung von Data-Mining-Methoden eine wesentlich breitere Untersuchung des simulierten Systems sowie eine höhere Komplexität in den abgeleiteten Erkenntnissen. Anforderungen an Simulationssysteme und –modelle zur Durchführung von Data-Farming werden erläutert. Eine Erweiterung des Ansatzes ist die simulationsbasierte Robustheitsanalyse auf der Basis von Verlustfunktionen nach Taguchi. Beide Vorgehensweisen werden an einer Fallstudie aus dem Fahrzeugbau demonstriert.
PPM based UWB System Throughput Optimisation

The system throughput performance of an synchronous ultra-wideband (UWB) communication system applying binary pulse position modulation (PPM) is investigated. The optimum impulse shift is analytically derived for the AWGN channel. The information throughput of an UWB system in AWGN channel has been optimized by adjusting the time overlap of the pulse shape used according to the actual signal-to-noise ratio (SNR).
Medicinska edukacija/ Medical education DIFFERENT ASPECTS OF OROFACIAL PAIN (PART II) NON-STEROID ANTIINFLAMATORY DRUGS FOR CHRONIC TEMPOROMANDIBULAR PAIN TREATMENT RAZLI^ITI ASPEKTI OROFACIJALNOG BOLA (DRUGI DEO) NESTEROIDNI ANTIINFLAMATORNI LEKOVI U LE^ENJU TEMPOROMANDIBULARNOG BOLA

Nonsteroidal anti-inflammatory drugs, usually abbreviated to NSAIDs but also referred to as nonsteroidal anti-inflammatory agents/analgesics (NSAIAs) or nonsteroidal anti-inflammatory medicines (NSAIMs) — are a class of drugs that provide analgesic and antipyretic (fever-reducing) effects, and in higher doses, anti-inflammatory effects. Although the use of analgesics for acute orofacial pain is well documented through hundreds of controlled clinical trials, the use of a broad spectrum of drugs for chronic orofacial pain is based on few studies. Toxicity associated with chronic administration of the drug can occur even in the absence of a therapeutic benefit. Recognition of the chronic adverse renal and gastrointestinal effects of NSAIDs indicates a need to examine critically their use for chronic pain conditions such as temporomandibular disorder (TMD).
The challenges and opportunities of the European Union lead market initiative : case bio-based products 1

© 2011 Institute of Business Administration 65 Journal of Business Chemistry 2011 8 (2) * University of Helsinki, Professor of Forest Products Marketing, Latokartanonkaari 7, 00014 Helsinki, anne.toppinen@helsinki.fi ** University of Helsinki,Master of Science, 42 Chaussée de Nivelles, 7170 Manage, meri.siljama@helsinki.fi Anne Toppinen*andMeri Siljama** Research Paper The challenges and opportunities of the European Union lead market initiative: case bio-based products