Miracle-dz/UniFAR-FTUs huggingface dataset:
Robust linear regression for high‐dimensional data: An overview

Digitization as the process of converting information into numbers leads to bigger and more complex data sets, bigger also with respect to the number of measured variables. This makes it harder or impossible for the practitioner to identify outliers or observations that are inconsistent with an underlying model. Classical least‐squares based procedures can be affected by those outliers. In the regression context, this means that the parameter estimates are biased, with consequences on the validity of the statistical inference, on regression diagnostics, and on the prediction accuracy. Robust regression methods aim at assigning appropriate weights to observations that deviate from the model. While robust regression techniques are widely known in the low‐dimensional case, researchers and practitioners might still not be very familiar with developments in this direction for high‐dimensional data. Recently, different strategies have been proposed for robust regression in the high‐dimensional case, typically based on dimension reduction, on shrinkage, including sparsity, and on combinations of such techniques. A very recent concept is downweighting single cells of the data matrix rather than complete observations, with the goal to make better use of the model‐consistent information, and thus to achieve higher efficiency of the parameter estimates.
Mitigation of premature ovarian failure by over-expression of lentivirus vector-mediated Wilms tumor-suppressor gene

Purpose: To investigate the effect of WT1(Wilms tumor-suppressor gene) overexpression on premature ovarian failure (POF)-mediated ovarian dysfunction. Methods: Three mice groups were used: control group (untreated mice), POF group (mice sterilized by intravenous injection of cyclophosphamide and busulfan), and POF-LV(lentiviral vector)􀀀GFP(green fluorescent protein)􀀀WT1 group (POF mice given intra-ovarian microinjection of LV􀀀GFP􀀀WT1, a WT1􀀀overexpressing lentiviral vector, one week after sterilization). Real time-PCR was employed to analyze in vitro WT1 overexpression levels. Overall ovarian function was measured by hormonal assay, H & E staining, and immuno-histochemical techniques. Results: Overexpression of WT1 in mice models of POF alleviated ovarian granulosa cell (GC) damage, increased ovary weight, and significantly increased follicular number (p < 0.05). Radioimmunoassays revealed reduction in plasma estradiol (E2) and follicle-stimulating hormone (FSH, p < 0.05). However, results from immune-histochemical assays showed reduced Bax expression levels, and increased expression of Bcl-2 in WTI-overexpression mice, relative to POF mice. Conclusion: Overexpression of WT1 may stimulate repair of ovarian tissue while improving endocrine function by inhibiting ovarian cell apoptosis signaling pathway in POF mice. Keywords: Premature ovarian failure, Wilms tumor suppressor gene, Chemotherapy, Apoptosis, Estradiol
Affordable Housing for Emiratis in the United Arab Emirates: The Case Study of Ras Al Khaimah

ABSTRACT Adequate and affordable housing is a basic human need, and in the United Arab Emirates (UAE), a federation composed of seven emirates, housing is treated as a constitutional right of every Emirati national. Using interviews with municipal and housing officials and a survey of the housing beneficiaries, the study evaluates the efficacy of the two national housing programs in the Emirate of Ras Al Khaimah that provide subsidies for affordable homeownership—the Sheikh Zayed Housing Program and the President’s Initiative. The study found that the UAE is shifting back to a provider approach to housing for its citizens. The program beneficiaries seemed satisfied with the design of their homes but raised concerns about their locations. The locations and growth spurred by the two programs have significantly shaped the current sprawling urban form of the Ras Al Khaimah municipality. The question of the long-term sustainability of the two programs looms large, funded as they are entirely by the government, with limited participation from the private, nonprofit, or informal sectors. To make housing programs financially and environmentally sustainable, every stakeholder must play a role: the federal government, the Emirate of Ras Al Khaimah, the Ras Al Khaimah Municipality, and the individual program beneficiaries.
Pemanfaatan Rhizobakteri dari Gulma di UB Forest sebagai Agen Antagonis Penyakit Layu Bakteri pada Kentang

Penyakit layu bakteri yang diakibatkan oleh patogen Ralstonia solanacearum merupakan kendala yang sering terjadi pada budidaya tanaman kentang. Penelitian bertujuan untuk mendapatkan rhizobakteri yang efektif mengendalikan penyakit layu bakteri dan meningkatkan pertumbuhan pada tanaman kentang. Penelitian dilaksanakan di Laboratorium Penyakit Tumbuhan Fakultas Pertanian Universitas Brawijaya, UB Forest, dan Desa Tulungrejo Kecamatan Bumiaji, Kota Batu. Rhizobakteri diisolasi dari perakaran gulma di UB Forest kemudian dilakukan pengujian aktivitas sebagai pemicu pertumbuhan. Rhizobakteri yang terpilih dilakukan pengujian sifat antagonis terhadap R. solanacearum secara in vitro dan penekanan terhadap angka kejadian penyakit serta pertumbuhan tanaman kentang. Identifikasi isolat dilakukan secara fisiologi, biokimia dan molekuler. Hasil eksplorasi didapatkan 20 isolat rhizobakteri yang bersifat antagonis terhadap R. solanacearum . Isolat AGR 2 memiliki diameter penghambatan yang sama dengan bakterisida secara in vitro . Secara in vivo isolat bakteri AGR 1, AGR 2 dan EPT 9 dapat meningkatkan rerata jumlah daun lebih tinggi dibandingkan dengan bakterisida pada 1 dan 2 MSA (minggu setelah aplikasi). EPT 9 mampu menekan angka kejadian penyakit layu bakteri 55,6 % setelah 5 MSA dan meningkatkan berat umbi sebesar 59,3 % lebih tinggi dari perlakuan kontrol. Isolat AGR 2 diketahui sebagai Pseudomonas aeruginosa dan EPT 9 merupakan Bacillus cereus .
Presence and Prevalence of Listeria Species in the Inci Kefali (Chalcalburnus tarichi, Pallas 1811)

Lake Van is not a very convenient environment for life of both sea and freshwater fish due to its high alkaline (pH 9.8) and salty (0.21%) water and only pearl mullet (Chalcalburnus tarichi, Pallas 1811) are present in the lake. In this study, the presence and prevalence of Listeria species in samples of the pearl mullet (Chalcalburnus tarichi, Pallas 1811) living as an endemic species in Lake Van and taken a total of 160 times for 12 months were examined. The method recommended by the United States Department of Agriculture/Food Safety and Inspection Service (USDA/FSIS) was used for the isolation and identification of Listeria species. Among the pearl mullet samples examined, Listeria spp. were isolated in 20 (12.50%) and of them L. innocua in 10 (6.25%) and L. welshimeri in 8 (5.00%) and L. ivanovii in 2 (1.25%) were identified. In this study, the presence of Listeria species in pearl mullet samples examined according to the seasons was revealed for the first time. Failure to identification of L. monocytogenes in any of the samples that is an important pathogen for humans, was assessed as an indicator that these fish did not constitute a public health risk in terms of listeriosis. As a result, Listeria spp. and other pathogenic microorganisms not to pose a risk to public health and in order to prevent the deterioration of fishes and reduce the economic losses, the transportation, storage and marketing of the caught fishes should be done under hygienic and cold conditions.
Off-Design Performance Prediction of a S-CO2 Turbine Based on Field Reconstruction Using Deep-Learning Approach

The reliable design of the supercritical carbon dioxide (S-CO2) turbine is the core of the advanced S-CO2 power generation technology. However, the traditional computational fluid dynamics (CFD) method is usually applied in the S-CO2 turbine design-optimization, which is a high computational cost, high memory requirement, and long time-consuming solver. In this research, a flexible end-to-end deep learning approach is presented for the off-design performance prediction of the S-CO2 turbine based on physical fields reconstruction. Our approach consists of three steps: firstly, an optimal design of a 60,000 rpm S-CO2 turbine is established. Secondly, five design variables for off-design analysis are selected to reconstruct the temperature and pressure fields on the blade surface through a deconvolutional neural network. Finally, the power and efficiency of the turbine is predicted by a convolutional neural network according to reconstruction fields. The results show that the prediction approach not only outperforms five classical machine learning models but also focused on the physical mechanism of turbine design. In addition, once the deep model is well-trained, the calculation with graphics processing unit (GPU)-accelerated can quickly predict the physical fields and performance. This prediction approach requires less human intervention and has the advantages of being universal, flexible, and easy to implement.
Variation in Dorsal Fin Morphology in Common Bottlenose Dolphin Tursiops truncatus (Cetacea: Delphinidae) Populations from the Southeast Pacific Ocean

Abstract: Variation in dorsal fin morphology was assessed in five common bottlenose dolphin populations from the Southeast Pacific. We hypothesized that habitat specialization between coastal and offshore ecotypes would lead to differences in dorsal fin morphology. Photographs and direct measurements of dorsal fins were used to calculate three indexes: height/length base (h/b), width at half height/length base (a/b), and overhang of the dorsal fin tip/length base (falcateness) (s/b). The sample included 163 individuals (129 coastal and 34 offshore) from Ecuador, 60 individuals (nine coastal and 51 offshore) from Peru, and 25 individuals of an inshore community occurring in north-central Chile (Pod-R). Ontogenetic variation was found in coastal dolphins from Ecuador, where sex and age classes were best represented. A statistically significant difference was found in the a/b index between coastal specimens from Ecuador and Peru and among the three offshore groups. When offshore and Pod-R data were pooled and compared with data from coastal specimens from Ecuador and Peru, a significant difference was found in the s/b index. Overall, dorsal fins of offshore dolphins are relatively higher than fins of coastal individuals. However, the most consistent difference between ecotypes was the strong falcateness (high s/b) in offshore forms versus a more triangular shape (low s/b) in coastal forms. We propose that dorsal fin falcateness is a reliable criterion to visually distinguish between bottlenose dolphin ecotypes in this region. Proper identification in the field greatly facilitates research and helps focus management needs of the different bottlenose dolphin populations.
Yoga’s Triadic Foundation

Obstinate intolerance, injustice or lies that favor privileged subgroups in today’s civilization depend on the roots of one-dimensional and dyadic paradigms. Certain interpretations and orientations of yoga are affected by this phenomenon. Paradigmatic shifts towards the triadic approach allow highlighting the philosophical richness of yoga and a better understanding of its tripartite complexity as science, art and technique. This article shines a light on the complexity inherent in that triple foundation.
Targeting Heat Shock Protein 70 to Improve Oxidative Stress and Mitochondrial Bioenergetics in Diabetic Sensory Neurons

Neuronal mitochondrial dysfunction is a key pathophysiologic mechanism of diabetic peripheral neuropathy (DPN). KU-596 is a small molecule modulator of heat shock protein 90 (Hsp90) that can reverse clinically relevant measures of DPN in diabetic animal models. Mechanistically, drug efficacy requires Hsp70 and correlates with improving mitochondrial bioenergetics (mtBE) in diabetic sensory neurons. The goal of this study was to determine if KU-596 improves mtBE by decreasing glucose-induced oxidative stress in an Hsp70-dependent manner. Sensory neurons were isolated from non-diabetic or diabetic mice wild type (WT) or Hsp70 knockout (Hsp70 KO) mice and treated ex vivo with KU596 in the presence of low or high glucose concentrations. In diabetic WT and Hsp70 KO neurons, hyperglycemia significantly increased superoxide levels, but KU-596 only decreased superoxide in WT neurons. Similarly, KU-596 significantly improved mtBE in hyperglycemically stressed diabetic WT neurons but did not improve mtBE in diabetic Hsp70 KO under the same conditions. Since manganese superoxide dismutase (MnSOD) is the main mechanism to detoxify mitochondrial superoxide radicals, we determined the cause and effect relationship between improved respiration and decreased oxidative stress by knocking down MnSOD. Downregulating MnSOD in diabetic WT neurons increased hyperglycemia-induced superoxide levels as measured by electron paramagnetic resonance spectroscopy and blocked the ability of KU-596 to enhance mtBE. In diabetic neurons, knockdown of MnSOD increased maximal respiratory capacity (MRC) and this was significantly decreased by mito-TEMPO-H after scavenging overproduced superoxide radicals. Following MnSOD knockdown, KU-596 decreased mitochondrial superoxide but was unable to improve MRC. Overall, this study shows that the Hsp90 inhibitor KU-596
Populations of Exotic × Locally Adapted Germplasm - A Potent

Experimental indigenous maize hybrids were evaluated in a series of three maize experiments during 2011, 2012 and 2013 to identify superior hybrids for commercial cultivation. Parental inbred lines of these hybrids were obtained from various indigenous populations, including a new improved maize population PSEV-3 which developed by the crossing of a locally adapted variety to an exotic hybrid obtained from CIMMYT and improved through S1 progeny recurrent selection. Two popular commercial hybrids namely, Babar (Public sector hybrid) and one Pioneer hybrid i.e., P-3025 were included as check genotypes. Results revealed that experimental PESV-3 derived hybrids revealed better performance by comparing with three check hybrids for grain yield (11.35 vs. 8.13 t ha-1, 10.67 vs. 9.60 t ha-1, and 11.69 vs. 11.20 t ha-1), thousand grain weight (372 vs. 338 g, 370 vs. 322 g, and 416 vs. 396 g), shelling % (87 vs. 86.2%, 86 vs. 85%, and 87 vs. 90%) and days to flowering (66.3 vs. 73.6 days, 64 vs. 67 days, and 69 vs. 68 days), respectively in three experiments. Three most superior hybrid combinations developed through exotic × locally adapted germplasm were found too much responsive and suggested their further testing through on-farm trials before releasing as commercial hybrids.
Workplace alcohol prevention: are managers' individual characteristics associated with organisational alcohol policy knowledge and inclination to initiate early alcohol interventions?

Individual factors associated with managers' organisational alcohol policy knowledge and inclination to initiate early alcohol interventions have been understudied. This study aims to examine differences in managers' policy knowledge and inclination across a range of socio-demographic, work-related and health characteristics, and it aims to examine the association between policy knowledge and inclination to intervene, net of these characteristics. ,Questionnaire data were collected from 430 managers. Organisational alcohol policy knowledge and inclination to intervene were measured using a 5-point Likert scale ranging from 1 (very low) to 5 (very high). Socio-demographic, work-related and health characteristics included gender, age, education, managerial responsibility, years in current position, self-rated health and alcohol consumption. Associations were examined using multilevel ordinal regression analysis. ,Managers with a greater number of employees demonstrated the highest level of organisational alcohol policy knowledge and were more inclined to initiate early alcohol interventions. Alcohol policy knowledge was associated with inclination to intervene, net of individual characteristics. ,Considering how managers' characteristics might influence efforts to decrease hazardous alcohol consumption is potentially important when designing future workplace alcohol prevention programmes. ,Several individual factors related to managers' organisational alcohol policy knowledge and inclination to initiate early alcohol interventions were identified, particularly managerial responsibility. However, the association between policy knowledge and inclination to intervene remained strong after accounting for these individual factors. Future studies should explore alternative explanations at the individual and organisational levels.
Managing Wildfire for Whitebark Pine Ecosystem Restoration in western North America

Wildfire in declining whitebark pine forests can be a tool for ecosystem restoration or an ecologically harmful event. This document presents a set of possible wildfire management practices for facilitating the restoration of whitebark pine across its range in Western North America. These management actions are designed to enhance whitebark pine resilience and health, while also being effective wildfire management measures. The actions are presented by the three phases of the wildfire continuum: Before, during, and after a wildfire. Current pre-wildfire restoration actions, such as mechanical thinning’s, prescribed burning, and fuel treatments, can also be designed to be fuel treatment activities that allow more effective suppression of wildfires when needed. Three wildfire strategies can be implemented while the wildfire is burning—full suppression, partial suppression, and wildland fire use (letting some fires burn under acceptable conditions)—for protecting valuable whitebark pine trees and for ecosystem restoration. Finally, post-wildfire activities include planting rust-resistant seedlings and monitoring effects of the wildfires. Recommended wildfire management practices for the wildfire continuum are specified by region, site type, and stand type in the last section of this paper.
Luminescence Analysis of Charge-Carrier Separation and Internal Series-Resistance Losses in 
Cu(In,Ga)Se2
 Solar Cells

This study investigates the phenomenon of $r\phantom{\rule{0}{0ex}}e\phantom{\rule{0}{0ex}}s\phantom{\rule{0}{0ex}}i\phantom{\rule{0}{0ex}}d\phantom{\rule{0}{0ex}}u\phantom{\rule{0}{0ex}}a\phantom{\rule{0}{0ex}}l$ $l\phantom{\rule{0}{0ex}}u\phantom{\rule{0}{0ex}}m\phantom{\rule{0}{0ex}}i\phantom{\rule{0}{0ex}}n\phantom{\rule{0}{0ex}}e\phantom{\rule{0}{0ex}}s\phantom{\rule{0}{0ex}}c\phantom{\rule{0}{0ex}}e\phantom{\rule{0}{0ex}}n\phantom{\rule{0}{0ex}}c\phantom{\rule{0}{0ex}}e$ from an illuminated solar cell under low or zero voltage bias---a luminescence that shouldn't be there, in an ideal solar cell. More broadly, the investigation shows that residual luminescence is a generic consequence of the finite coupling strength between the electron-hole system inside the photovoltaic absorber and the external electrical circuit. For the important case of a classic $p\ensuremath{-}n$ junction, the authors derive an analytical expression for this coupling strength, and for experiments with a real Cu(In,Ga)Se${}_{2}$ solar cell, they offer an in-depth analysis of the efficiency losses resulting from the finite coupling. The conclusions of this work apply to $a\phantom{\rule{0}{0ex}}n\phantom{\rule{0}{0ex}}y$ solar cell.
Role of Tyr-39 for the Structural Features of α-Synuclein and for the Interaction with a Strong Modulator of Its Amyloid Assembly

Recent studies suggest that Tyr-39 might play a critical role for both the normal function and the pathological dysfunction of α-synuclein (αS), an intrinsically disordered protein involved in Parkinson’s disease. We perform here a comparative analysis between the structural features of human αS and its Y39A, Y39F, and Y39L variants. By the combined application of site-directed mutagenesis, biophysical techniques, and enhanced sampling molecular simulations, we show that removing aromatic functionality at position 39 of monomeric αS leads to protein variants populating more compact conformations, conserving its disordered nature and secondary structure propensities. Contrasting with the subtle changes induced by mutations on the protein structure, removing aromaticity at position 39 impacts strongly on the interaction of αS with the potent amyloid inhibitor phthalocyanine tetrasulfonate (PcTS). Our findings further support the role of Tyr-39 in forming essential inter and intramolecular contacts that might have important repercussions for the function and the dysfunction of αS.
Quality of experience‐driven resource allocation in vehicular cloud long‐term evolution networks

To improve user experience and allocate reasonably spectrum resources, the quality of experience (QoE) for user is introduced as an indicator to express the user's satisfaction with the service provided. The QoE‐driven resource allocation optimization algorithm for orthogonal frequency‐division multiple is designed to maximize the user's QoE and optimize resource allocation in vehicular cloud (VC) long‐term evolution (LTE) networks. Therein, a novel QoE model which reflects delay, transmission rate, and service price by mean opinion score (MOS) is proposed to identify different services. Furthermore, the characteristics of delay, transmission rate, and service price are also analyzed specifically at different time slots, respectively. Simulation results show that the proposed resource allocation algorithm could achieve a better QoE in the field of user satisfaction and throughput compared with other traditional algorithms, especially when the number of vehicles is greater than 30 or 22, respectively. Meanwhile, the impact of fairness on QoE and throughput are also improved apparently when the number of vehicles is small. In end, the QoE‐mode brings performance improvements on delay, transmission rate, and service price compared with other single X mode.
Participative leadership and employee creativity: a sequential mediation model of psychological safety and creative process engagement

The purpose of this paper is to draw upon social information processing theory to examine the sequential mediating roles of psychological safety and creative process engagement between participative leadership on creativity. ,Using a time-lagged sample of 526 supervisor–subordinate dyads from RD psychological safety significantly mediates the relationship between participative leadership and creative process engagement; creative process engagement significantly mediates the relationship between psychological safety and employee creativity; psychological safety and creative process engagement sequentially mediates the relationship between participative leadership and creativity. ,The study findings imply that the participative leadership behaviors of managers or supervisor's nurtures employees psychological safety to take risk and promotes employee engagement in creativity relevant ventures leading to creativity. ,The findings contribute new knowledge on the relationship between participative leadership and creativity by uncovering the causal chain of a cognitive mechanism (psychological safety) with a behavioral mechanism (creative process engagement).