Miracle-dz/UniFAR-FTUs huggingface dataset:
An Inversion-Based Model Predictive Control With an Integral-of-Error State Variable for Piezoelectric Actuators

Piezoelectric actuators have been widely employed in various nanopositioning systems. Hysteresis exhibited by piezoelectric actuators can degrade their behavior, and thus the tracking performance of positioning systems. To improve the performance of the systems, control of hysteresis has been drawing considerable attention. One of the issues that remain to be addressed in the controller design is how to deal with the constraints (e.g., the input voltage) that might be applied to the piezoelectric actuators. To avoid overloading the piezoelectric actuators, the mechanism of saturation is typically employed in control schemes, which, however, can degrade the control performance. This paper presents the development of an inversion-based model predictive control with an integral-of-error state variable to compensate for the piezoelectric-actuator hysteresis. The proposed method allows for the consideration of constraints in the controller design. Theoretical proof of the zero steady-state error and disturbance rejection properties of the proposed method is also provided. To verify the effectiveness of the control method, experiments were conducted with the results showing that the proposed method can improve the performance of piezoelectric actuators.
Identification and detecting of attacker in a purchase portal using honeywords

Honeywords are originated by the user details given and the authenticated password is changed to another format and saved with honeywords. We deploy intermediate server, shopping server for purchase and Cloud server for maintaining user account details. The hacker notices and email account of original user can easily change the password of the cloud server. The attackers are persuaded to undertake attack, to find out very easily. Now if the unauthorized person tries to access purchase page, they are tracked unknowingly and permitted to purchase. The adversary is identified by the server and redirects the user details to the genuine person and also seals the hacker performing transaction process from their real account.
Quel renouveau pour la sociologie économique

Presentation du numero L’objectif poursuivi par ce numero d’Interventions economiques consacre a la sociologie economique est de faire le point sur des apports novateurs de chercheurs nord-americains et europeens œuvrant dans ce domaine disciplinaire. Les points de vue developpes dans les articles inclus dans ce numero permettent ainsi d’illustrer des courants forts de la « nouvelle sociologie economique », tout en indiquant la richesse de travaux en cours, incluant ceux lies a l’analyse inst.
The Effect of Left Subclavian Artery Coverage During Endovascular Repair of the Thoracic Aortic Aneurysm on Cerebral Hemodynamics: Two Cases of Flow Measurement by using 2D Phase Contrast Magnetic Resonance Imaging

The proximity of thoracic aortic aneurysm to the left subclavian artery (LSA) has made the coverage of LSA during thoracic endovascular aortic repair (TEVAR) be essential. Despite controversy concerning the safety of LSA coverage and the indications for LSA revascularizations, the cerebral hemodynamic change after LSA coverage has not been demonstrated. We prospectively examined two patients who would undergo TEVAR with LSA coverage by using 2D cine phase contrast MR imaging. After LSA coverage, the left subclavian steal was properly compensated by the increased flow volumes of both carotid arteries and right vertebral artery, which is the major collateral supply. The total brain supply after TEVAR did not lessen, which showed good correlation with uneventful clinical outcome. Therefore, 2D phase contrast MR imaging can be recommended as a useful technique to evaluate the hemodynamic change of the LSA coverage during TEVAR and to triage the candidate for LSA revascularization.
Solid-state experiments at high pressure and strain rate

Experiments have been developed using high powered laser facilities to study the response of materials in the solid state under extreme pressures and strain rates. Details of the target and drive development required for solid-state experiments and results from two separate experiments are presented. In the first, thin foils were compressed to a peak pressure of 180 GPa and accelerated. A pre-imposed modulation at the embedded Rayleigh–Taylor unstable interface was observed to grow. The growth rates were fluid-like at early time, but suppressed at later time. This result is suggestive of the theory of localized heating in shear bands, followed by conduction of the heat into the bulk material, allowing for recovery of the bulk material strength. In the second experiment, the response of Si was studied by dynamic x-ray diffraction. The crystal was observed to respond with uni-axial compression at a peak pressure 11.5–13.5 GPa.
Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation.

Interaction Modules Directing Cell Regulation Kim Van Roey,† Bora Uyar,† Robert J. Weatheritt,‡ Holger Dinkel,† Markus Seiler,† Aidan Budd,† Toby J. Gibson,† and Norman E. Davey*,†,§ †Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany ‡MRC Laboratory of Molecular Biology (LMB), Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, United Kingdom Department of Physiology, University of California, San Francisco, San Francisco, California 94143, United States
Secure cyber incident analytics framework using Monte Carlo simulations for financial cybersecurity insurance in cloud computing

The remarkable increasing demands of mitigating losses from cyber incidents for financial firms have been driving the rapid development of the Cybersecurity Insurance (CI). The implementations of CI have covered a variety of aspects in cyber incidents, from hacking to frauds. However, CI is still at its exploring stage so that there are a number of dimensions that are uncovered by the current applications. The cyber attack on critical infrastructure is one of the serious issues that prevents the expansions of CI. This paper addresses CI implementations focusing on cloud‐based service offerings and proposes a secure cyber incident analytics framework using big data, named as Cost‐Aware Hierarchical Cyber Incident Analytics (CA‐HCIA). The approach is designed for matching different cyber risk scenarios, which uses repository data. We use Monte Carlo simulations for extracting the incident features based on the training datasets. The main algorithms in CA‐HCIA include Monte Carlo Cyber Feature Extraction (MC2FE) and Optimal Cost Balance (OCA) Algorithms. Our experimental evaluation has provided the theoretical proof of the adoptability and feasibility. Results show that our proposal improves the cost of existing techniques in 7.98% and 15.39%. Copyright © 2016 John Wiley & Sons, Ltd.
Lack of Association of the 11beta-hydroxysteroid dehydrogenase type 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen production, blood pressure, glucose metabolism, and dementia.

CONTEXT Recently, it was proposed that a combination of the 83,557insA polymorphism in the 11beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene and the R453Q polymorphism in the hexose-6-phosphate dehydrogenase (H6PD) gene interacts to cause cortisone reductase deficiency (CRD) when at least three alleles are affected. OBJECTIVE The aim was to study the separate and combined effects of these polymorphisms on body composition, adrenal androgen production, blood pressure, glucose metabolism, and the incidence of dementia in the healthy elderly population. DESIGN/SETTING/PARTICIPANTS The Rotterdam study (n = 6105) and the Frail Old Men study (n = 347) are population-based cohort studies in the elderly. MAIN OUTCOME MEASURES Genotype distributions and influences of (combined) genotypes on body mass index, adrenal androgen production, waist to hip ratio, systolic and diastolic blood pressure, fasting glucose levels, glucose tolerance test, and incidence of dementia were measured. RESULTS No influence of the HSD11B1 83,557insA (allele frequencies 22.0 and 21.5%) and H6PD R453Q (allele frequencies 22.9 and 20.2%) variants was found for the different outcome measures that were investigated, either separately or when at least three alleles were affected. CONCLUSIONS Two population-based studies among Caucasian elderly showed no evidence for (combined) effects of two polymorphisms in the HSD11B1 and H6PD genes on body composition, adrenal androgen production, blood pressure, glucose metabolism, and incidence of dementia. Moreover, the high frequencies observed for these two polymorphisms do not correspond to the low incidence of CRD observed in the general population. Altogether, it is unlikely that these polymorphisms cause CRD.
Analysis and Control of Wind Farm Incorporated VSC-HVDC in Unbalanced Conditions

With increasing attention to sustainable development and environmental protection, more and more countries turn to wind energy to reduce their dependence on traditional fossil fuel energy. Among the new challenges with this trend is how to integrate wind farm with existing AC network more effectively. The paper presents a possible measure based on VSC-HVDC, namely so-called wind farm incorporated VSC-HVDC (WVSC-HVDC). In the paper the wind farm along with an AC grid supplies to a passive network. The paper firstly introduces VSC-HVDC, and then presents a space vector based control strategy for supplying to a passive network. The rectifier controls DC voltage and reactive power that is needed by the wind farm. The inverter controls the AC bus voltage in the passive network. Simulations using PSCAD/EMTDC are performed to study the steady and transient behaviors of WVSC-HVDC. With harmonics analysis, the simulation results will be helpful for further understanding of the operation characteristics of WVSC-HVDC and its protection design
Rumpshaker: an X‐linked mutation affecting CNS myelination. A study of the female heterozygote

This study examines the myelin deficits found in the spinal cord and optic nerves of female mice heterozygotes for rumpshaker (rsh), an X‐linked mutation causing hypomyelination. No clinical abnormalities were detected but morphological changes were evident, particularly in the spinal cord, which showed no evidence of resolving with age. In the spinal cord, scattered hypomyelinated axons, occasionally grouped in twos or threes, were the major feature; oligodendrocyte numbers were slightly elevated at all ages compared to normal male littermates and the total amount of myelin was reduced. Myelin protein composition of the sheaths was examined by immunostaining for myelin basic protein (MBP) and two peptide regions of PLP/ DM‐20 molecule; one being proteolipid protein (PLP)‐specific and the other recognizing the c‐terminal common to PLP‐DM‐20. The majority of myelin sheaths immunostained for MBP and PLP. Occasional MBP‐positive sheaths failed to stain with PLP/DM‐20 or PLP‐specific antiserum. Therefore, at least two types of immunocytochemically‐defined myelin sheaths are present in the heterozygotes. Changes in the optic nerves were much less obvious; glial cell numbers were increased but thinly myelinated axons were not detected although the total amount of myelin was reduced compared to normal littermates. In no instance were mosaic, amyelinated/ hypomyelinated patches detected. Heterozygotes for rsh, therefore, are considerably different from those for other X‐linked myelin mutations like the jimpy mouse and the myelin‐deficient rat, both in regard to the severity of the lesions and their failure to recover with age.
Magnetic resonance imaging in patients with a subcutaneous implantable cardioverter-defibrillator

Aims Our aim was to evaluate the potential for safely imaging patients with a new type of implantable cardioverter-defibrillator called the subcutaneous implantable cardioverter-defibrillator (S-ICD) in a 1.5 T magnetic resonance imaging (MRI) scanner. With the increasing number of patients with cardiac implantable devices who are indicated for MRI, there is a growing need for establishing MRI compatibility of cardiac implantable devices. Methods and Results Patients with implanted S-ICD systems underwent one or more types of anatomical MRI scans. The S-ICD was programmed off and patients were monitored throughout the imaging procedure. Device function was evaluated pre- and post-scan. Patients were asked to report immediately any pain, torqueing movement, or heating sensation in the area of the pocket or electrode. Fifteen patients underwent a total of 22 examinations at 1.5 T. Scans included brain, spine, knee, and heart. Two patients were re-scanned due to complaints of heating over the can during lumbar scans, which was caused by a thermistor probe placed on the skin to measure skin temperature. All the remaining scans occurred without incident. No evidence of device malfunction was observed. Conclusion This study is the first to domonstrate the feasibility of exposing S-ICD patients to MRI using the scanning and monitoring protocol described. More data are required to support S-ICD as a MRI conditional device.
Identification des catégories de produits issus de catalogues publicitaires

RÉSUMÉ. Nous proposons dans cet article une approche d’extraction d’informations, basée sur une ontologie, et appliquée à des documents issus de catalogues publicitaires. Les documents des catalogues sont des descriptifs de produits relativement pauvres. Les informations à ex-traire, ou annotations, concernent les catégories et les caractéristiques des produits considérés, répertoriées dans une ontologie de domaine. L’extraction d’informations concernant un pro-duit consiste en un peuplement de cette ontologie, plus précisément le peuplement des concepts représentant ses catégories et ses caractéristiques. La relative pauvreté des descriptifs rend ir-réalisable un peuplement totalement automatique. Nous proposons donc une approche en deux étapes : (1) une première étape d’annotation semi-automatique qui porte sur un petit ensemble de documents ; (2) une deuxième étape qui annote l’ensemble des autres documents de façon entièrement automatique, en s’appuyant sur des mécanismes d’apprentissage automatique ex-ploitant les résultats de la première étape. L’originalité de ce travail consiste en une approche incrémentale de rafﬁnement des informations extraites. Le travail
A Systematic Review of the Evidence for Central Nervous System Plasticity in Animal Models of Inflammatory-mediated Gastrointestinal Pain

Background:Abdominal pain frequently accompanies inflammatory disorders of the gastrointestinal tract (GIT), and animal models of GIT inflammation have been developed to explore the role of the central nervous system (CNS) in this process. Here, we summarize the evidence from animal studies for CNS plasticity following GIT inflammation. Methods:A systematic review was conducted to identify studies that: (1) used inflammation of GIT organs, (2) assessed pain or visceral hypersensitivity, and (3) presented evidence of CNS involvement. Two hundred and eight articles were identified, and 79 were eligible for analysis. Results:Rats were most widely used (76%). Most studies used adult animals (42%) with a bias toward males (74%). Colitis was the most frequently used model (78%) and 2,4,6-trinitrobenzenesulfonic acid the preferred inflammatory agent (33%). Behavioral (58%), anatomical/molecular (44%), and physiological (24%) approaches were used alone or in combination to assess CNS involvement during or after GIT inflammation. Measurement times varied widely (<1 h–> 2 wk after inflammation). Blinded outcomes were used in 42% studies, randomization in 10%, and evidence of visceral inflammation in 54%. Only 3 studies fulfilled our criteria for high methodological quality, and no study reported sample size calculations. Conclusions:The included studies provide strong evidence for CNS plasticity following GIT inflammation, specifically in the spinal cord dorsal horn. This evidence includes altered visceromotor responses and indices of referred pain, elevated neural activation and peptide content, and increased neuronal excitability. This evidence supports continued use of this approach for preclinical studies; however, there is substantial scope to improve study design.
Improving the management of nitrate pollution in water by the use of isotope monitoring: the δ15N, δ18O and δ11B triptych

In spite of increasing efforts to reduce nitrogen inputs into ground water from intensive agriculture, nitrate (NO3) remains one of the major pollutants of drinking-water resources worldwide, with NO3 levels approaching the defined limit of 50 mg l−1 in an increasing number of water bodies. Determining the source(s) of contamination in water is an important first step for improving its quality by emission control. The Life ISONITRATE project aimed at showing the benefit of a multi-isotope approach (δ15N and δ18O of NO3, and δ11B), in addition to conventional hydrogeological analysis, to track the origin of NO3 contamination in water. Based on land use and local knowledge, four distinct cases were studied: (1) natural soil NO3, (2) natural denitrification, (3) single source of NO3 pollution and (4) multiple sources of NO3 pollution. Our results show the added value of combining isotope information, compared to knowledge based on local authorities’ experience, land use and the ‘classical’ chemical approach, by efficiently identifying the number and type of NO3 source(s) for each watershed studied.
Imaging of the Rotator Cuff

The imaging evaluation of the rotator cuff augments the clinical evaluation. Radiography, computed tomography, and magnetic resonance imaging all have various roles in the assessment of the rotator cuff, which can be combined with arthrography for added detail. Furthermore, ultrasound is a very useful technique that provides functional information that is not offered by simple anatomic imaging.
Basic physics of MR contrast agents and maximization of image contrast

This review summarizes the physical basis of magnetic resonance (MR) imaging contrast agents, including both T1 agents, such as gadolinium‐DTPA (diethylenetri‐aminepentaacetic acid), and T2 or T2* agents, such as superparamagnetic iron oxides. The maximization of image contrast and lesion visibility with contrast agents is described, and the use of contrast agents in MR angiogra‐phy and perfusion imaging is discussed.
Microscopic study of superionic transition.

The mechanism of superionic transition is discussed both phenomenologically and microscopically in the framework of the ``chemical bond peculiarities'' approach which was originally proposed by Phillips. The proximity of p-halogen and d-metal electronic levels is proved to be a critical prerequisite to the formation of a local additional minimum of crystalline potential. The fold coordination number change involved in the transition is regarded as a redistribution of ionic occupancies, rendering this additional minimum absolute. The low-energy excitations are ascribed to the ionic motion between the local and absolute potential minima, with their consequent appearance both at temperatures below and above the phase transition. \textcopyright{} 1996 The American Physical Society.
Entropy as a lens into LDA model understanding

Latent Dirichlet Allocation (LDA) has seen increasing application to source code and its related artifacts in part because of its impressive modeling power. However, this expressive power comes at a cost: the technique includes several tuning parameters whose impact on the resulting LDA model must be carefully considered. The goal of this work is to highlight the initial promise of combined entropy as a technique for better understanding the tuning parameters' impact. Doing so aims to improve the effectiveness of both researchers seeking to exploit the power of LDA in their work and tool users who must interpret the output of LDA-using tools. Initial results obtained using seven production systems find that combined entropy shows very little variation from system to system indicating that it has strong external validity. These results also highlight how effective combined entropy can be as a lens for understanding LDA's potential value to downstream applications.
neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice

Thirty percent of human breast cancers have amplification of ERBB2, often in conjunction with mutations in p53. The most common p53 mutation in human breast cancers is an Arg-to-His mutation at codon 175, an allele that functions in a dominant oncogenic manner in tumorigenesis assays and is thus distinct from loss of p53. Transgenic mice expressing mouse mammary tumor virus-driven neu transgene (MMTV-neu) develop clonal mammary tumors with a latency of 234 days, suggesting that other events are necessary for tumor development. We have examined the role of mutations in p53 in tumor development in these mice. We have found that 37% of tumors arising in these mice have a missense mutations in p53. We have directly tested for cooperativity between neu and mutant p53 in mammary tumorigenesis by creating bitransgenic mice carrying MMTV-neu and 172Arg-to-His p53 mutant (p53-172H). In these bitransgenic mice, tumor latency is shortened to 154 days, indicating strong cooperativity. None of the nontransgenic mice or the p53-172H transgenic mice developed tumors within this time period. Tumors arising in the p53-172H/neu bitransgenic mice were anaplastic and aneuploid and exhibited increased apoptosis, in distinction to tumors arising in p53-null mice, in which apoptosis is diminished. Further experiments address potential mechanisms of cooperativity between the two transgenes. In these bitransgenic mice, we have recapitulated two common genetic lesions that occur in human breast cancer and have shown that p53 mutation is an important cooperating event in neu-mediated oncogenesis.
Energy efficiency of a new trifocal intraocular lens

The light distribution among the far, intermediate and near foci of a new trifocal intraocular lens (IOL) is experimentally determined, as a function of the pupil size, from image analysis. The concept of focus energy efficiency is introduced because, in addition to the theoretical diffraction efficiency of the focus, it accounts for other factors that are naturally presented in the human eye such as the level of spherical aberration (SA) upon the IOL, light scattering at the diffractive steps or the depth of focus. The trifocal IOL is tested in-vitro in two eye models: the aberration-free ISO model, and a so called modified-ISO one that uses an artificial cornea with positive spherical SA in instead. The SA upon the IOL is measured with a Hartmann-Shack sensor and compared to the values of theoretical eye models. The results show, for large pupils, a notorious reduction of the energy efficiency of the far and near foci of the trifocal IOL due to two facts: the level of SA upon the IOL is larger than the value the lens is able to compensate for and there is significant light scattering at the diffractive steps. On the other hand, the energy efficiency of the intermediate focus for small pupils is enhanced by the contribution of the extended depth of focus of the near and far foci. Thus, while IOLs manufacturers tend to provide just the theoretical diffraction efficiency of the foci to show which would be the performance of the lens in terms of light distribution among the foci, our results put into evidence that this is better described by using the energy efficiency of the foci.