Miracle-dz/UniFAR-FTUs huggingface dataset:
Incipient Syphilitic Papillitis

ABSTRACT Patients with syphilis can present with optic disc oedema (ODE) without visual compromise, which has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. We report four cases of ODE in the setting of syphilis with preserved visual function, normal intracranial pressure, and no enhancement of the optic nerve or sheath on magnetic resonance imaging. We propose the term “incipient syphilitic papillitis” for cases presenting with ODE, preserved vision and absence of optic nerve sheath enhancement, which is likely a more common presentation than syphilitic optic perineuritis.
Analysis of MHC-I homologues in molluscum contagiosum and human cytomegalovirus

Molluscum contagiosum virus (MOCV) and human cytomegalovirus (HCMV) each encode two MHC-I homologues: mc080 and mc033 in MOCV, UL18 and UL142 in HCMV. Codon optimised versions of the mc080 and mc033 genes were cloned in to a second-generation lentivirus system, vaccinia virus and a replicationdeficient adenovirus (Ad) vector. MOCV mc033 and mc080 were expressed from the Ad vector as endoglycosidase H (EndoH) sensitive glycoproteins with apparent molecular weights of 64kDa and 44kDa respectively, both localised predominantly to the ER. MC033 had no effect on either MHC-I or HLAE expression, nor did it impact NK cells or T cell function. MC080 downregulated cell surface expression of classical HLA-I and HLA-E in a TAP independent, although not MICA/B. This downregulation of HLA-1 correlated with protection against CD8+ T cell activation, thus MC080 is here identified as a novel viral T cell evasion function. MC080 was capable of supressing or activating NK cell, depending on context and consistent with MC080’s control of HLA-I and HLA-E. UL142 expression was enhanced by optimising codon usage and through provision of an alternative leader sequence. Using an Ad vector, UL142 was expressed as a heavily glycosylated 105kDa protein that localised to the ER, cell surface and was released into the supernatant in an EndoH-resistant form. When over-expressed from the Ad vector UL142 suppressed full length MICA, but not in the context of a productive HCMV infection where that function was performed by the US12 gene family. Preliminary allogenic functional NK cell assays showed UL142 to suppress NK cell function in one of four donors. However, cell-associated and secreted UL142 both activated NK cell degranulation when the assay was moved to an autologous setting. The results suggest that UL142 can modulate NK cell function independently of MICA.
Introductory Chapter: Current and Future Trends in the Diagnosis and Management of Uveitis

Uveitis represents a significant burden of visual loss causing around 10–15% of all cases of blindness in the United States, and it is the fifth cause of visual loss in the developed world, accounting for up to 20% of legal blindness [1]. Visual loss due to uveitis currently has a significant impact on the productivity and quality of life of many patients worldwide. Therefore, advances in research and development of diagnostic techniques and therapeutic strategies are crucial for patients suffering from many forms of infectious and autoimmune intraocular inflammation. One of the main obstacles that ophthalmologists face on diagnosis and treatment of eye disease is the unique complexity of the physical and physiological barriers, as well as the delicate anatomical structures of the human eye. This biologic scenario, particularly in highly destructive tissue disorders like infectious and autoimmune uveitis, represents a challenge for early and accurate diagnosis and effective therapy. Even today, with all possible diagnostic resources available in tertiary eye care facilities, more than 30% of patients suffering from uveitis do not have a definitive etiologic diagnosis [2]. The same is true for current therapeutic methods which suffer from lack of specificity, and are limited to availability at the site of inflammation due to the complex anatomical and physiological characteristics of the eye [3]. Therefore, the development of improved diagnostic methods and therapeutic modalities for inflammatory ocular disorders has recently received special and intense attention by the uveitis research community.
And diverse are their hues : color in Islamic art and culture

The Koran uses the phrase 'and diverse are their hues' to describe the glorious chromatic variety of God's creation. Colour has always been an important signifier in Islamic art, and its uses have encompassed the practical as well as the mystical and poetic. This comprehensive volume is the first to analyze the use of colour in Islamic art and architecture from a range of artistic and cultural perspectives. A prestigious team of international scholars discusses the applications and implications of colour in Islamic cultures from medieval to modern times and from Central Asia to Spain and beyond. They look at art, architecture, literature, philosophy, mysticism, optics, and conservation studies. Amply and vividly illustrated, "And Diverse Are Their Hues" is also a remarkable visual resource for Islamic carpets, ceramic tiles, manuscripts, gardens, and buildings.
Health care in the United States: How the determinants of health insurance status differ across regions

Using a nationally representative sample of individuals across all fifty United States from the 2016 American Community Survey (ACS), this research explores differences in the incidence and predictors of health insurance status across region (i.e. West, Midwest, South, and Northeast) for individuals age 18 and older. The data suggests that: 1) Individuals from the Northeast are the most likely to have some form of health insurance, while individuals from the South are the least likely; 2) The factors which influence health insurance status are relatively similar across all regions, though they often differ substantially in magnitude; 3) In some cases region can play a significant role in determining the type of insurance an individual has (i.e. Public versus Private). Policy makers will find these results useful to target specific factors within regions that may prove to increase the number of insured individuals. Furthermore, researchers may choose to use this paper as a current reference and starting point for further in-depth analysis on targeted factors within specific regions. Un ive rsi ty of Ca pe To wn The copyright of this thesis vests in the author. No quotation from it or information derived from it is to be published without full acknowledgement of the source. The thesis is to be used for private study or noncommercial research purposes only. Published by the University of Cape Town (UCT) in terms of the non-exclusive license granted to UCT by the author.
Bowel Obstruction: Differential Diagnosis and Clinical Management

Here is a practical guide to the diagnosis and management of obstruction, both mechanical and organic, of the large and small bowel. Obstruction is a common problem for surgeons, and this text emphasizes differential diagnosis and the use of all radiologic modalities. It presents the surgical and medical considerations involved with gallstones, bezoars, parasites, tumors, inflammation, trauma, intussusception, more.
Retrospective study of the prevalence of Recurrent Aphthous Ulcer

The prevalence of Recurrent Aphthous Ulcer (RAU) is varied in different regions of the world. There is insufficient survey in prevalence of RAU in Malaysia as the only latest figure available is about 18 years ago. This study aimed to measure the prevalence of RAU in patients attending Dental Clinic-college of dentistry within 5 academic years and to know the distribution and relation of RAU based on the most common type of RAU, gender, race and age range. A retrospective cross-sectional study based on the confirmed case of RAU from the students’ Oral Medicine logbooks and case sheets from the attended patients’ folder to Oral Medicine Dental Clinic- college of dentistry from academic year 2012/2013 to 2016/2017. 160 patients were diagnosed of RAU.0. 42% of prevalence among the total patients was found to have RAU. As compared between the Oral Medicine cases, patients that were diagnosed with RAU shows prevalence of 11.13%. The most common type was minor RAU (96.9%), followed by major (3.1%) and no patient was presented with herpetiform type. Based on gender, females showed more predilection of RAU compared to males with 60.6%. Age range of 20-29 showed the highest percentage of 71.3 % and Malay showed the most common race of RAU compared to Chinese and Indian which was 97.4%. The results indicate there is a relation between the type of RAU, age, gender, race and with the prevalence of RAU. Further studies should include larger sample size with a wider range of populations.
Pleiotropic Roles of Cytokines in HIV-1 Pathogenesis and Control: A Literature Review

Introduction: Human Immunodeficiency Virus 1 (HIV-1) is a retrovirus that infects human immune cells, primarily CD4+ T cells and macrophages. During HIV-1 disease progression, infected individuals have declining CD4+ T cell counts and increasing HIV-1 RNA, indicative of virus replication. Numerous studies have identified important roles for cytokines in immune responses during the course of HIV-1 infection. Cytokines are small molecular weight proteins that communicate signals between a broad range of cells in the immune system. This review aims to highlight a key subset of cytokines that bear potential as targets for the prevention and treatment of HIV-1 infection. Methods: We conducted a literature review categorizing pertinent cytokines on the basis of four criteria: correlations with HIV-1 replication, impact on host innate immune cells, characteristic expression in elite controllers, and therapeutic applications. Results: We identified several cytokines in the interleukin (IL) family and the C-C and C-X-C chemokine families with important roles in HIV-1 control. Indeed, the expression of many cytokines was correlated with reduced HIV-1 replication (e.g. IL-21, IL-32, IL-27). Several cytokines directly impact cells of the innate immune system in their HIV-1 control mechanisms. Among many, IL-7 and IL-15 are able to enhance natural killer cell function, while IL-27 enhances macrophage resistance to HIV-1 infection. Elite controllers, individuals who have suppressed HIV-1 replication and preserved CD4+ T cell levels without exogenous antiviral drug treatment, express a uniquely characteristic array of chemokines. Namely, CCL14, CCL27, CCL21, XCL1 and CXCL12 are upregulated in elite controllers compared to non-controllers. Finally, considering the diversity and pleiotropic roles of cytokines during HIV-1 infection, many show potential for inclusion in therapeutic designs. Conclusion: Herein, we have highlighted the antiviral roles of several cytokines, demonstrating that many cytokines are key regulators of HIV-1 replication. This work provides a focus for future research aiming to better understand HIV pathogenesis and informs novel preventative and therapeutic designs.
Modified Propofol-Ketamine Cosmetic Surgery: Anesthesia Technique for Surgeon-Administered Anesthesia with Particular Reference to Liposuction

Propofol-ketamine (PK) anesthesia was originally described by Friedberg as dissociative monitored anesthesia care (MAC), which gives the patient the subjective experience of general anesthetic with few risks and virtually no postoperative nausea, vomiting, dysphoria, or hallucinations. Friedberg has a stellar 10-year record of safety with patients receiving propofol-ketamine anesthesia, with a 0.5% postoperative nausea and vomiting (PONV) rate. There were no hospitalizations in his group for either uncontrolled pain or PONV, the 2 most common reasons for admission following day surgery. For the surgeon who chooses to administer his or her own anesthesia, this paper describes a variation of Friedberg's original work. (See www.doctorfriedberg.com for other information.)
The effect of direct-acting antivirals on hepatocellular carcinoma recurrence: still waiting for the turning point.

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide accounting for about 9% of all cancer deaths (1). The natural history of HCC is extremely variable due to high effectiveness of treatment only in early stages and low overall survival rate in patients with advanced disease who are poor responders to any treatment. Unlike other cancers, HCCs usually develop in patients with underlying liver disease that limits the use of chemotherapy and radiotherapy for the high risk of complications (2).
Shift of paradigm needed towards improving human–elephant coexistence in monoculture landscapes in Sabah

This article outlines the contemporary situation of the Bornean elephant Elephas maximus borneensis in Sabah (Malaysian Borneo), and focuses on the existing challenges that need to be addressed to enable people and elephants to coexist, particularly in man‐made landscapes dominated by oil‐palm plantations. Bornean elephants are confined mostly to Sabah, to the north‐east 5% of the Borneo Island. Sabah started to expand its commercial plantation sector in the early 1980s and is the largest producer of palm oil in Malaysia, contributing c. 10% of global output for this commodity. The rapid pace of plantation expansion has resulted in the loss of the majority of lowland areas that are also needed by large mammal species to sustain breeding populations. Elephants are extreme lowland/floodplain specialists, and they still attempt to use their former and preferred habitat, which is now mostly dominated by oil‐palm plantations. At the time of writing, the land‐use planning system favoured by the government insufficiently incorporates the ecological and management needs for elephants across the entire landscape. This article also highlights the need for better collaboration and coordination between stakeholders to address the increasing rate of human–elephant conflicts in Sabah.
New insights into the wasting mechanisms of chronic disease

Catabolism in connection with disorders may be considered as an inevitable consequence of the disease or even as a physiological adaptation. Consequently, treatment focused against the emaciation in disease is often given low priority. However, the understanding of intrinsic mechanisms involved in the wasting of chronic disorders, its deleterious long-term effects and potential treatment possibilities has evolved largely in recent years, thus giving hope for the future development of complementary treatment modalities for diseases complicated by nutritional perturbations.
A Literature Review of Musculoskeletal Disorders in Handicraft Sector

This research review article made an attempt to review such issues pertaining to handicraft sector. It highlight/covers following aspects in detail: ergonomics interventions in handicraft industries, occupational risk factor, and musculoskeletal disorders. The literatures over a decade reported that ergonomics concepts are more applied in large-scale industries like steel plant, power plant, manufacturing plants, automotive sectors etc. rather than small-scale industries like handicraft. However, applying ergonomics concepts/principles in such industries would definitely lead to increase in the work-system-worker productivity by improvement in tools, methods, work-environment, minimizing injuries and disorders. Based on literature studies recommendations are made that significant lead to improvement in productivity of such industries. KEywoRDS Environment, Ergonomics, Musculoskeletal Disorders, Performance, Productivity, Workstations
Histoire de la pensée arabe et islamique

La pensee arabe et islamique est vieille de seize siecles et s’etend sur deux continents. C’est une pensee plurielle dans son inspiration comme dans son evolution, riche de debats, de controverses et de dissidences, ou sauvegarde de la tradition et desir d’innovation se cotoient, se succedent ou s’affrontent. Doctrines religieuses, systemes philosophiques, theories scientifiques et engagements politiques s’y entrecroisent. Sunnites, chiites, mystiques soufis, mais aussi Arabes chretiens ou judeo-Arabes en sont, au cote de beaucoup d’autres, les acteurs. De l’examen des valeurs coraniques a l’etude de la crise de l’islam contemporain, des moments fondateurs aux evenements tragiques qui marquerent les debuts du troisieme millenaire : pour apprehender cette histoire trop meconnue, il manquait un livre de reference. Le voici.
An introduction to testing web applications with twill and selenium

This Short Cut is an introduction to building automated web tests using two tools, twill and Selenium. twill is a simple web scripting language that can be used to automate web tests, while Selenium is a web testing framework that runs in any browser and can be used to test complex web sites that make extensive use of JavaScript. The best way to use this Short Cut is to run through the examples. We expect that within an hour you can start writing your own functional tests in either twill or Selenium, and within a day you will understand most, if not all, of the possibilities and the limitations of these tools.
Importancia de algunas frutas, verduras y hortalizas en la prevención de la diabetes mellitus tipo II / The Importance of some fruits and vegetables in the prevention of diabetes mellitus type II

Los vegetales y frutas son extremadamente importantes en la nutricion humana como fuente de nutrientes y para la reduccion de riesgo a desarrollar ciertas enfermedades cronicas. Dentro de este grupo de enfermedades se encuentra la diabetes mellitus, la cual es una enfermedad de origen multifactorial, caracterizada por un grupo de desordenes metabolicos que dan origen a la hiperglicemia cronica, uno de los sintomas caracteristicos de esta enfermedad. Historicamente, para el tratamiento se han empleado diversos medicamentos, pero recientemente se ha hecho evidente la importancia de la dieta en el control y la prevencion de esta enfermedad.
MiTV: rethinking interactive TV

After studying what is being developed in the interactive TV (iTV) field, we wanted to point out what we consider bad interface design and terrible interaction choices that the industry is currently on its way to make. In this paper, we propose new, more natural and more "interactive", approaches for iTV applications. And since we have already implemented most of them using our own distributed architecture, we'll go through some concrete examples. The next big step is to conduct some user studies with these applications on "real" people.
Testing women, testing the fetus

Rich with the voices and stories of participants, these touching, firsthand accounts examine how women of diverse racial, ethnic, class and religious backgrounds perceive prenatal testing, the most prevalent and routinized of the new reproducing technologies. Based on the author's decade of research and her own personal experiences with amniocentesis, Testing Women, Testing the Fetus explores the "geneticization" of family life in all its complexity and diversity.
Evaluation of urgent caesarian according to colour code at the Befelatanana University Hospital Centre of Obstetric Gynecology in Antananarivo Madagascar

Background: Color code was described for the first time in 2003 was described for the first time in 2003 by since and al. The objective of this study was to accomplish urgent caesarian sections according to color code over delays indications-births (DIN) in Motherhood Befelatanana, Antananarivo, Madagascar.Methods: It was about a longitudinal prospective, analytical study of caesarian sections performed in emergency in CHUGOB going from June 1st till December 31st, 2017.Results: Authors took a census 193 caesarian sections of emergency. Among these patients 28 (14.50%) had a caesarian section encode red, 42 (21.76%) an orange code and 123 (63.73%) a green code. The medium age of the patients was of 26.4 years and that of the gestation was of 37SA and 6 days. The delay indication-birth (DIN) medium was of 102.9 minutes for red code, 99.7 minutes for orange code and 75 minutes for green code.Conclusions: Authors could not attain DIN of 30 minutes shape in international recommendations. Authors must improve the delay indication entered in the surgical unit by reinforcing knowledge of the agents of support on the management of emergency obstetrical. The possibility of leading to a very quick birth is an indisputable progress in obstetrics but she should not make forget risks inherent in such procedure.
Audio-Motor Synchronization Tests For Cognitive Functions Assessment In Children With Cns Lesions

Children with pediatric cancer usually treated with chemoand radiotherapy. Because of such treatment, psychologists and health professionals declare cognitive and motor abilities decline in cancer patients. Timing is extremely important for movement and speech, and understanding the neurobiological basis of rhythm perception and reproduction can be helpful in addressing motor and cognitive recovery after brain lesions. The aim of our study was to investigate audio-motor synchronization abilities in children with different nervous system lesions. Our sample included 98 children, divided into three groups. The first group was consisted of children treated for posterior fossa tumors, mostly medulloblastoma and astrocytoma (PFT-group, n = 44, mean age 12.09  2.92 years). Our results suggest that degree of brain damage after cancer and treatment is associated with ability to synchronize arm movements with auditory cues (PFT > ALL > control). Healthy children are able to anticipate stimuli, but ALL and especially PFT patients mostly reacted after stimulus onset. © 2018 Published by Future Academy www.FutureAcademy. org.UK
Characterizing large object-oriented software: a topological perspective

The increase of the software complexity makes how to understand software systems a hard work. Since you cannot control what you cannot measure, many research works have been done on software metrics. But one key property has always been neglect, i.e., the topological properties of software systems. In this paper, we proposed to analyze object-oriented (OO) software systems from the perspective of software topological property. First, OO software systems are represented by network at method and class level, respectively. Then we introduce complex network theory to analyze the topological properties of these networks. A case study on an open source OO software system, JHotDraw 5.1, gives an illustration of our approach. Our approach can give further understanding of OO software systems.
Stereovision for dynamic analysis of human body movement

The aim of this paper is to describe a new Stereovision Laboratory. It was designed and constructed by the authors of the paper in the University of Valencia. It consists of four cameras with its special equipment, a moving track, hardware and software for calculation and visualization. The tests carried out on the measurement stand lead to obtain the set of data describing the movement of human body. The stored data serves to analyze static and dynamic behavior of some parts of human body like arms, legs or vertebral column. Special software was design in order to do visual inspection of the movement and to select a proper data.