Miracle-dz/UniFAR-FTUs huggingface dataset:
Book Review: Making Consumer Education Effective: Proceedings of the Second National Conference on Consumer Education

serve this free market by preventing "the private seizure of power over interstate commerce. " To those persons who feel that there may be other causes than restraints of trade for the inability of our system to produce and distribute at capacity, Mr. Arnold gives absolutely no attention. But to those who say that the Sherman Act has failed, he has a very definite answer-we have never really tried to enforce it. If the Anti-trust Division of the Department of Justice is provided with men and funds he feels that it will not be found "a difficult task to maintain a free market. " He would use the one-industry-ata-time approach and gradually force restraints out of existence; to keep them from reappearing one or two men would be stationed in each major city to act as the "eyes and ears" of the law. And to those who say that the Sherman Act is nothing but a restraining hand on bigness, he would reply that it is nothing of the kind. It is opposed to restraints of trade, regardless of whether they are found in big or in little businesses. Even to one who is sympathetic with Arnold's general point of view, it may seem that he is far too optimistic as to the ease with which restraints may be abolished from the American scene. Yet to many economists it should come as a welcome change to have a person with his view engaged in enforcing our anti-trust laws. The Bottlenecks oj Business, as is to be expected by those who read The Fokelore oj Capitalism, is well written, although it lacks some of the wit and vitality of the earlier book. Even such a dull topic as procedure under the Sherman Act is approached so as to carry the reader through it without hesitation. Perhaps the weakest part of the book is a miscalled chapter on "The Rise of A Consumer Movement. " It should also be noted that there is no attempt to place a dividing line between that part of our economic system which should be dominated by a free market and that part which should be under some degree of government control. The reader will also look in vain for any discussion of the relation of Mr. Arnold's thesis to Fair Trade laws. In spite of these criticisms, one need have no hesitation in recommendTHE JOURNAL OF MARKETING
HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression*

At present, HOXC13 is the only member of the HOX multigene family that produces a fragile hair phenotype when mutated or overexpressed in mice. To determine whether hair keratin genes are targets for this transcription factor, we analyzed the HOXC13 responsiveness of human hair keratin genes, whose expression matched that of nuclear HOXC13, immunologically revealed in cells of the lower hair-forming compartment of the human anagen hair follicle. We show that HOXC13, but not a homeobox-deleted HOXC13, strongly activated the promoters of the genes, with the respective proximal promoter regions being sufficient for optimal activation. The hair keratin promoters contained numerous putative Hox binding core motifs TAAT, TTAT, and TTAC. Electrophoretic mobility shift assays revealed that HOXC13 bound exclusively to distinct TAAT and TTAT core motifs that were clearly concentrated in the proximal promoter regions. A comparison of the sequences flanking HOXC13 binding and nonbinding core motifs, respectively, allowed the deduction of an extended 8-bp HOXC13 consensus binding sequence TT(A/T)ATNPuPu. Thus, the DNA binding conditions for HOXC13 were distinct from those of other members of the paralogous group 13, i.e. murine Hoxb13 and HOXd13, for which previous investigations yielded the consensus binding sequence TTTA(T/C)NPuPu. Collectively, our data speak for a direct involvement of HOXC13 in the control of hair keratin expression during early trichocyte differentiation.
Impact of computerized accounting information systems’ effectiveness in increasing the efficiency of human capital

The study aimed to identify the impact of Computerized Accounting Information Systems‘ effectiveness in increasing the efficiency of human capital in the financial departments in the public Sri Lankan universities. The population of this study consists of all employees in the financial departments in fifteen Sri Lankan public universities. The sample was selected from the three public universities which are located in Eastern province in Sri Lanka. Conclusion of this study has explained the significant model. The variables interpret the positive correlation and the significant relationship with the level of the skill and the innovation with the efficiency of computerized accounting information system in finance department of the Sri Lankan public universities.
Automatic cellularity assessment from post‐treated breast surgical specimens

Neoadjuvant treatment (NAT) of breast cancer (BCa) is an option for patients with the locally advanced disease. It has been compared with standard adjuvant therapy with the aim of improving prognosis and surgical outcome. Moreover, the response of the tumor to the therapy provides useful information for patient management. The pathological examination of the tissue sections after surgery is the gold‐standard to estimate the residual tumor and the assessment of cellularity is an important component of tumor burden assessment. In the current clinical practice, tumor cellularity is manually estimated by pathologists on hematoxylin and eosin (H&E) stained slides, the quality, and reliability of which might be impaired by inter‐observer variability which potentially affects prognostic power assessment in NAT trials. This procedure is also qualitative and time‐consuming. In this paper, we describe a method of automatically assessing cellularity. A pipeline to automatically segment nuclei figures and estimate residual cancer cellularity from within patches and whole slide images (WSIs) of BCa was developed. We have compared the performance of our proposed pipeline in estimating residual cancer cellularity with that of two expert pathologists. We found an intra‐class agreement coefficient (ICC) of 0.89 (95% CI of [0.70, 0.95]) between pathologists, 0.74 (95% CI of [0.70, 0.77]) between pathologist #1 and proposed method, and 0.75 (95% CI of [0.71, 0.79]) between pathologist #2 and proposed method. We have also successfully applied our proposed technique on a WSI to locate areas with high concentration of residual cancer. The main advantage of our approach is that it is fully automatic and can be used to find areas with high cellularity in WSIs. This provides a first step in developing an automatic technique for post‐NAT tumor response assessment from pathology slides. © 2017 International Society for Advancement of Cytometry
A Hyper-Dk Piggyback Contact Lens System for Keratoconus

Purpose To report the fitting of a hyper-Dk piggyback contact lens system in a case of keratoconus. Methods Case report. Results A patient with keratoconus, suboptimal visual acuity, corneal neovascularization, and marked conjunctival hyperemia, who was intolerant of rigid gas-permeable contact lenses, was fitted with a novel piggyback contact lens system that incorporated a hyper-oxygen transmissible hydrogel contact lens, on top of which was fitted a hyper-oxygen transmissible rigid gas-permeable lens. This novel contact lens system provided a significant improvement in visual acuity, comfort, and lens wear time. There was a marked reduction in corneal vascularization and ocular hyperemia. Conclusions This hyper-Dk piggyback contact lens system satisfied the ocular and visual requirements of this patient, for whom other nonsurgical options for vision correction had been unsuccessful. This system has potential application in the visual rehabilitation of other cases of corneal irregularity, including unsuccessful refractive surgery, ocular trauma, and keratoplasty. Piggyback contact lens systems require the same level of expertise to fit as basic forms of soft and rigid contact lenses. The hyper-oxygen transmissible lens materials available make these dual-lens systems a viable option for the compromised cornea.
2 . 2 Wavelet Based Video Coding

EZW, a wavelet transformation based compression algorithm, utilizes the correlations of the wavelet coefficients between subbands. Due to the reason that, it is based on Zero Tree’s parent-descendant dependency of the subbands, subband coding is possible, but it is not efficient for applications, which require multiresolution restorations. In this paper we compare and analyze the performance between spatial band coding, which apply the correlation between adjusting pixels, and EZW. So as to prove that spatial band coding is superior to EZW in the sense that it exhibit higher PSNR values and that it is apt to multiresolution restoration.
Computational finite element analyses to optimize graft sizing during aortic valve-sparing procedure.

BACKGROUND AND AIM OF THE STUDY Aortic valve-sparing (AVS) procedures have been introduced to treat ascending aorta dilatation and aortic valve insufficiency in the presence of preserved native aortic valve leaflets. Although the surgical technique has been standardized, the choice of best type and size of Dacron graft to be used remains a matter of debate. Herein are presented preliminary results based on a patient-specific finite element model aimed at optimizing the Dacron prosthesis size and shape. Previously, finite element analysis (FEA) has been applied to investigate medical problems and, in particular, to better evaluate the pathophysiology of the aortic root. To date, however, such methodology has not been applied to the patient-specific evaluation of AVS postoperative results. METHODS The framework of the FEA study included four steps: (i) the creation of a mathematic model of the patient's aortic root; (ii) the creation of a model for two different Dacron grafts (the standard straight graft and a Valsalva graft), with sizes of each type ranging from 24 to 30 mm; (iii) a virtual computer-based simulation of the AVS procedure, using each graft; and (iv) a virtual computer-based simulation of the diastolic closure of the repaired valve and an evaluation of post-implant physiology, based on three parameters: the height of coaptation ratio (H(C)R); the length of coaptation ratio (L(C)R); and the distance between the central point of coaptation and the ideal geometrical centre (D(C)). RESULTS The simulation results of post-implant performance of the aortic valve revealed that both H(C)R and L(C)R were decreased as the graft size was increased, but no significant differences were identified between two types of graft. In contrast, the Valsalva graft, when compared to the standard straight graft, led to a significant reduction in D(C). The results in terms of H(C)R, L(C)R and D(C) recommended unequivocally, for the specific case under investigation, that a 30 mm straight graft and a 28 mm Valsalva graft would ensure the most physiological valve behavior for the patient under investigation. CONCLUSION In evaluating the potential of a preoperative prediction of the optimal graft size, using FEA, the virtual simulation of the AVS procedure proved to be feasible and useful in predicting the postoperative physiology of the aortic root. In particular, this finite element model might have a clinical impact as may be used to optimize the surgeon's choice of prosthesis size.
Specific Design Considerations for Cloud Accounting Mobile Apps

In the era of rapid application development which emphasizes heavily the rapid prototyping and iterative delivery, it is imperative that software developers take the time to properly plan the software development phases. With the emergence of cloud computing and mobile cloud computing software developers are tempted to jump in and write code without planning. This practice can lead to resource waste, thus making the use of software development methodologies an imperative. This paper proposes five UML diagram models for a cloud accounting app.
Millimeter‐wave phase shifter based on waveguide‐mounted RF‐MEMS

A continuously variable transmission type W‐band phase shifter based on a single pole bandpass filter tuned by MEMS actuated fingers is reported. Tuning is achieved by means of two half‐wavelength long conductive fingers that synchronously rotate upwards in an antiparallel fashion. The fingers deflection results in a distributed variable shunt capacitance which in turn leads to a variable analog phase shift. For an applied DC bias voltage between 0 and 26 V, the transmission phase can be continuously varied up to 46.4° at a frequency of 106 GHz with an insertion loss of less than 3.4 dB. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:465–468, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27390
Three-dimensional isotropic scalar metamaterial with Drude dispersion for the permittivity and permeability

In this contribution we present a topological analysis of metamaterials, which can describe one-, two-, and three-dimensional structures. Using this approach a novel three-dimensional metamaterial scalar structure is deduced, i.e., it supports one polarisation having left-handed operation. Its physical realisation has Drude dispersion for ∈eff, μeff and obeys Th symmetry, ensuring isotropy. Full-wave eigenmode simulations show a 30% relative bandwidth of left-handed operation.
Predicting Personality Traits, Gender and Psychopath Behavior of Twitter Users

Social networking sites, such as Facebook and Twitter, are quickly becoming one of the most popular tools for social interaction and information exchange. Users of social networks reveal a lot about themselves in their public profiles, photos and status updates. While, social networks request users to create a truthful representation of themselves, they actually do so with a varying degree of accuracy. Depending on their privacy attitudes, the users may choose not to share details they find sensitive or tend to provide fake information. Contrary to a number of previous studies to predict the personality traits of the users of social networks primarily based on the users' profiles and other publically available information, this study provides an insight into the personality traits and psychopath behavior of twitter users by analyzing the tweets. The authors predict personality traits along the dimensions of "Big Five" personality model, gender and psychopath behavior of Twitter users. The paper discusses our data collection, gender, personality traits and psychopathic behavior prediction tool. It presents the analysis results of 327672 tweets of 345 users. The results show that there are more male users than the female users 70% male and 30% female. The results also show that majority of Twitter users are open to new ideas, are more agreeable and conscientious in nature but are less extravert. Out of 345 users, nine were indicating psychopath behavior and show less neuroticism. The authors also present a comparison of our personality traits' results with the results of two other similar studies.
Synchronization of tool tip and tool orientation contour errors in five-axis machining

In current CNC machines, each axis is generally controlled by an individual controller, which tries to minimize the axial position tracking error. However, eliminating the tracking errors of each individual axis in multi-axis feed drive systems may not guarantee the desired contouring accuracy. Tracking errors in individual driving axis result in tool tip contour error and tool orientation contour error during five-axis machining. Based on the conventional definition of the tool orientation contour error, which is defined as deviation in the normal direction from the desired orientation in spherical coordinates, even if the tool tip contour error and tool orientation contour error are very small, a mismatch between the tool tip position and tool orientation causes an overcut or undercut when these errors are treated independently. In order to avoid this mismatch, this paper presents a new definition of the actual tool orientation contour error that considers the synchronization between the tool tip contour error and tool orientation contour error. In addition, an estimation model for the tool orientation contour error is proposed. Simulation results demonstrate that the proposed model gives a better indication of the actual tool orientation contour error than the conventional definition.
Ocular surface extracellular DNA and nuclease activity imbalance: a new paradigm for inflammation in dry eye disease.

PURPOSE We determined whether nucleases are deficient in the tear fluid of dry eye disease (DED) patients, and whether this causes extracellular DNA (eDNA) and neutrophil extracellular trap (NET) accumulation in the precorneal tear film, thus causing ocular surface inflammation. METHODS Exfoliated cells adhered to Schirmer test strips were collected on glass slides, and immunofluorescence confocal microscopy was used to evaluate neutrophils, eDNA, NETs, and their molecular components. Similar experiments were performed with mucoid films collected from the inferior conjunctival fornix or bulbar conjunctiva. We used quantitative PCR to evaluate eDNA signaling pathways and inflammatory cytokine expression. We also determined the amount of ocular surface eDNA and evaluated tear fluid nuclease activity. RESULTS eDNA, NETs, and neutrophils were present on the ocular surface in DED patients and abundant in mucoid films. NETs consisted of eDNA, histones, cathelicidin, and neutrophil elastase. Tear fluid nuclease activity was decreased significantly in DED patients, whereas the amount of eDNA on the ocular surface was increased significantly. Expression of genes downstream of eDNA signaling, such as TLR9, MyD88, and type I interferon, as well as the inflammatory cytokines interleukin-6 and tumor necrosis factor-α, was significantly increased in DED patients. CONCLUSIONS Extracellular DNA production and clearance mechanisms are dysregulated in DED. Nuclease deficiency in tear fluid allows eDNA and NETs to accumulate in precorneal tear film, and results in ocular surface inflammation. These findings point to novel therapeutic interventions in severe DED based on clearance of eDNA, NETs, and other molecular components from the ocular surface.
The ColR–ColS two‐component signal transduction system is involved in regulation of Tn4652 transposition in Pseudomonas putida under starvation conditions

Bacteria use two‐component signal transduction pathways to sense both extracellular and intracellular environment and to coordinate cellular events according to changing conditions. Adaptation can be either physiological or genetical. Here, we present evidence that a genome reorganization process such as transposition can be controlled by certain environmental cues sensed by a two‐component signal transduction system. We demonstrate that transposition‐dependent accumulation of phenol‐utilizing mutants is severely decreased in Pseudomonas putida defective in a two‐component system colRS. Translocation of Tn4652 is decreased both in colR‐ and colS‐defective strains, indicating that signal transduction from a histidine kinase ColS to a response regulator ColR is necessary for the activation of Tn4652 in bacteria starving on phenol. However, overexpression of ColR in a colS‐defective strain restores Tn4652 transposition, suggesting that absence of the signal from ColS can be compensated by an elevated amount of ColR. In vitro analysis of purified ColR and ColS proteins evidenced that they constitute a functional phosphorelay. Site‐directed mutagenesis revealed that a conserved H221 can be the phosphoryl‐accepting residue in ColS and that aspartate residues D8 and D51 of ColR are necessary for the phosphotransfer from ColS to ColR. To our knowledge, Tn4652 is the first bacterial transposon regulated by a two‐component system. This finding indicates that transpositional activity can respond to signals sensed and processed by the host.
Robotic-Assisted Partial Nephrectomy: Experience on 60 Cases

Introduction Laparoscopic partial nephrectomy is still one of the more challenging procedures in urology. Minimizing warm ischemia time (WIT) and bleeding requires efficient intracorporeal suturing. In addition, achieving negative surgical margins requires complete excision of the tumor. Robotic-assisted partial nephrectomy (RALPN) adds the advantages offered by the “Da Vinci system” to laparoscopy, such as the 3-D vision, and the better degree of freedom of surgical instruments. Objective The objective of this study is to report our experience with RALPN. Methods From August 2009 to October 2012, 60 patients underwent RALPN for kidney cancer. The average age of the patients (35 female, 25 male) was 63 (range 48–80) years. Average BMI was 25 (range 21.8–29.7) kg/m2. Average tumor size was 3.2 cm (range 2-6.7 cm). All the procedures were performed by a transperitoneal approach, liar clamping was used in all cases: in 47 patients by one intracorporeal tourniquet for the artery and one for the vein; in three cases, ilar clamping was “en block” by Satinsky. Results Mean operative time was 167.2 min (140–250) with a WIT of 23.8 min (15–28). The mean estimated blood loss was 260 mL (50–300). In one case, nephrectomy was necessary because the tumor involved the renal pedicle. One patient had pulmonary embolism and one urinary leakage conservatively managed. Pathologic examination revealed clear cell renal cell carcinoma in 58 patients, oncocytoma in one patient, and angiomyolipoma in one patient. All resection margins were free from tumor. Conclusions Partial nephrectomy, facilitated by robotic technology, is more and more frequently performed as a safe and effective minimally invasive procedure.
Development of an Integrative Relationship in the Care of the Breastfeeding Newborn : Lactation Consultant and Chiropractor

There is a growing consensus among psychologists, midwives, lactation consultants, physicians and others who are concerned with the early perinatal period that there is a “sensitive period” (Odent, Klauss) immediately following a physiologically normal birth. During this brief period a very unique hormonal milieu, orchestrated by the birth itself, drives maternal-infant interactions. These interactions are designed to wire the mother and infant for attachment, directing them toward behaviors that optimize the infant’s potential, first for survival and ultimately for well-being.
Assessing Progressive Filtering to Perform Hierarchical Text Categorization in Presence of Input Imbalance

The more the amount of available data (e.g., in digital libraries), the greater the need for high-performance text categorization algorithms. So far, the work on text categorization has been mostly focused on “flat” approaches, i.e., algorithms that operate on non-hierarchical classification schemes. Hierarchical approaches are expected to perform better in presence of subsumption ordering among categories. In fact, according to the “divide et impera” strategy, they partition the problem into smaller subproblems, each being expected to be simpler to solve. In this paper, we illustrate and discuss the results obtained by assessing the “Progressive Filtering” (PF) technique, used to perform text categorization. Experiments, on the Reuters Corpus (RCV1v2) and on DZMOZ datasets, are focused on the ability of PF to deal with input imbalance. In particular, the baseline is: (i) comparing the results to those calculated resorting to the corresponding flat approach; (ii) calculating the improvement of performance while augmenting the pipeline depth; and (iii) measuring the performance in terms of generalization/ specialization/ misclassification-error and unknown-ratio. Experimental results show that, for the adopted datasets, PF is able to counteract great imbalances between negative and positive examples.