Miracle-dz/UniFAR-FTUs huggingface dataset:
Network Dynamics in an Interorganizational Telemedicine Network: A longitudinal qualitative case study of the large-scale TeleCare North Program

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Scientific Opinion on the essential composition of total diet replacements for weight control

Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on the essential composition of total diet replacements for weight control. Total diet replacements for weight control are intended to induce a substantial energy deficit in overweight or obese adults who wish to lose weight and replace the whole diet in the context of energyrestricted diets for weight reduction. In this opinion, the Panel proposed a minimum protein content based on a Population Reference Intake for protein adjusted for the overweight or obese (75 g/day), a minimum carbohydrate content based on the obligatory glucose demands of the brain (30 g/day) and minimum contents of linoleic acid (11 g/day), α-linolenic acid (1.4 g/day) and micronutrients based on reference values established either by the Panel or by other scientific or authoritative bodies. Derived from the minimum content of macronutrients, the Panel proposed a minimum energy content of total diet replacements for weight control of 2 510 kJ/day (600 kcal/day). The Panel also advised on potential conditions and restrictions of use for these products. © European Food Safety Authority, 2015
Multiple stream job performance optimization with source operator graph transformations

Multiple distributed stream queries, which are executed on stream processing systems, need to be fine‐tuned to the compute cluster in order to harness the full potential of the hardware they run on. In this paper, we describe an automatic technique for conducting such stream query optimization in the presence of multiple stream jobs. During this autotuning process, we identify the structure of each program and conduct automatic program transformation to generate optimized unified streaming jobs. The operators on the unified secondary sample application are grouped into processing elements considering their performance characteristics and the stream graph topology structure to produce high performance stream query network. We implemented this multiple stream query optimization technique on a mechanism called Tahitica. We demonstrate our approach's ability for producing optimized stream query performance by comparing it to naive deployments using two real‐world stream processing applications in the domains of health care and search advertising. Our stream query optimization approach reported 7.1% throughput performance improvement compared to a naive deployment.
Livestock Feeds Assessment in Southern Highlands in Tanzania

Introduction Livestock contributes significantly to Tanzania’s agricultural GDP being the second country in Africa after Ethiopia in cattle population (Thornton et al., 2002). Like in most African countries, inadequate feed resources contribute to the underperformance of the sector. Animals are under fed, and therefore genetic potential not fully utilized (Mwendia et al., 2018.). Feeds and forages contribute significantly to the requirements of a successful livestock enterprise. Up to 70% of the costs involved are attributed to feeds and forages (Odero-Waitituh 2017) conversely implying importance of addressing the feeding component. Albeit the need to improve use of suitable forages, understanding the agricultural context in question is paramount. This includes looking at the livestock systems, matching forages with the correct ecologies and the social-cultural background of the communities involved in order to increase chances of adoption. The work reported here was therefore set out to assess the farming context and role of livestock involvement in household incomes in three districts in Tanzania highlands in order to inform subsequent forage interventions.
Complementary and Integrative Therapies for the Management of Insomnia in Chronic Disease: An Applied Research Project

One-half of all adults in America have a diagnosis of at least one chronic disease. Up to 80% of people with chronic diseases suffer from insomnia, creating a significant health burden. Healthcare providers (HCPs) do not routinely address insomnia and primarily use pharmaceuticals to manage insomnia. The purpose of this research is to co-create with HCPs an educational artifact that helps them inform their chronically ill patients about evidence-based complementary and integrative therapies (CIT) for insomnia management. Based on a design and development culture of inquiry and research method, we used the literature to create a preliminary educational artifact focused on four evidence-based CIT for insomnia management: aromatherapy, mindfulness meditation, relaxation and breathing techniques, and yoga. These modalities are safe, inexpensive, and accessible from home for individuals with chronic disease. We collected evaluative feedback from a convenience sample of HCPs. The top two factors impacting HCP integration of CIT into practice are lack of reimbursement and time constraints. HCPs support an artifact that addresses affordable, accessible, evidence-based modalities to complement conventional treatments for insomnia management. Since these integrative practices may be unfamiliar to some HCPs, our research confirms that an accessible educational artifact may effectively support the integration of aromatherapy, mindfulness meditation, relaxation and breathing techniques, and yoga into mainstream practices. We conclude our applied research with recommendations for the key components of an educational artifact.
A Meta-Analysis of 20 Randomized Trials of a PCI-Based Strategy in Patients With Stable Coronary Artery Disease

As the role of percutaneous coronary intervention in the management of stable coronary artery disease compared to optimal medical treatment is still controversial, the aim of the present analysis was the evaluation of the impact on long-term mortality of these two treatment options in patients with symptoms or signs of myocardial ischemia but no acute coronary syndrome. A total of 20 randomized trials including 9679 patients were identified. The analysis showed no statistically significant differences regarding overall mortality, cardiac death or myocardial infarction.
Estimation of efficacy of Startvac® vaccination in dairy herds

Ynte Schukken, Paolo Moroni , Clara Locatelli, Francesco Testa, Licia Scaccabarozzi, Claudia Pollera, Nicola Rota, Antonio Casula and Valerio Bronzo College of Veterinary Medicine, Cornell University Università degli Studi di Milano, Department of Health, Animal Science and Food Safety, Via Celoria 10, Milan, Italy Università degli Studi di Milano, Department of Veterinary Pathology, Hygiene and Public Health, Via Celoria 10, Milan, Italy
“Eco Green Ular Tangga (EGUT)” Game as Tools of Teaching to improve Environmental Care for Early childhood in Tunas Bangsa and Jati Asih Play Groups in Semarang

PAUD (Play Groups) Tunas Bangsa and PAUD Jati Asih are institutions that position parents as partners in the preparation and personal development from an early age, providing guidance to play groups and kindergartens in the Ngaliyan area of Semarang. Two institutions of Early Childhood Education that will become partners in the Community Partnership Program (PKM). Dra. Tri Edi Mhanani as the principal of Tunas Bangsa PAUD school and Ibu Sri Lestari Raahayu P., A.Md as the principal of Jati Asih PAUD school have the same topic, namely not having education related to environmental goals. Educational props of the ladder snake game (EGUT) can help improve children's cognitive and psychomotor abilities. Children will learn to analyze colors, recognize letters, socialize, jump, throw, all of which are positive things in children's development. The material and features provided can help children to love the environment.
Matrix Inductor With DC-Bias Effect Reduction Capability for GaN-Based DC-DC Boost Converter

In this brief, a 400-W Gallium Nitride device based DC-DC boost converter with a four phase matrix inductor is proposed. It is well-known that there is a significant influence of the DC bias on inductor core losses and the simplest solution is to employ multiphase structures. However, the size of the converter will also increase as the number of phases increases. Therefore, in order to achieve both high efficiency and high power density, a matrix inductor is proposed for four phases boost converter. The proposed matrix inductor retains the flux sharing advantages of conventional inductors with E-cores and thus greatly increases the power density and utilization rate, by integrating the inductors through flux cancellation. Therefore, both the size and the core loss are reduced when compared with four conventional inductors. Moreover, since the four phases are operated in parallel, the phase error, which is a critical problem in the interleaved structure, may not affect the proposed converter, removing the current balance issue. Critical operation mode is utilized to achieve zero-voltage switching (ZVS) for all switches. Finally, the proposed four phase DC-DC boost converter and matrix inductor is built and tested to verify its feasibility. The peak and CEC efficiency is tested to be 99.3% and 99.1%, respectively.
An exploration of why women with breast cancer symptoms present late in seeking treatment at Komfo Anokye Teaching Hospital, Ghana

INTRODUCTION: In line with most developing African countries about 85% of breast cancer patients who attend Komfo Anokye Teaching Hospital (KATH), Ghana, present with stage III/IV disease. This study aimed at understanding what factors influence health seeking behaviour and the decision to seek help in women with breast cancer symptoms. METHOD: Women presenting for the first time with clinical stage III/IV breast cancer symptoms to KATH breast clinic were purposively selected for the study between May 2015 and March 2016. In-depth interviews were conducted to explore the women’s symptom appraisal process and the events that prompted health seeking. The Andersen behavioural model for health service use was the conceptual basis for the thematic analysis, with a critical realist perspective. Interpretation of how the identified factors interacted with each other and how they ultimately evolved to influence decision making was done. RESULTS: Fifteen women were interviewed. They were aged between 24 – 79 years. Ten of them had symptoms consistent with clinical stage III and 5 had clinical stage IV breast cancer. Time from symptom identification to attending KATH was 4 - 24 months. The first symptom identified was a breast lump or breast swelling. These were initially appraised as “normal/not serious” because they did not affect the woman’s daily functioning. The trigger to seek medical help was worsening of their symptom such that daily function was affected. At this stage, the women were willing to do whatever was required to access healthcare. Misunderstanding of the investigations required and the referral process also contributed to their late presentation to KATH. CONCLUSION: Women appraise their breast symptoms as not needing medical attention until they worsen. Opportunities at first hospital presentation to educate women with breast symptoms on the value of investigations and the need to follow through with referrals could potentially influence health seeking behaviour of women with breast cancer symptoms positively.
Barriers to Preventive Healthcare for Immigrants in Michigan

Barriers to Preventive Healthcare for Immigrants in Michigan by Sondos Ghazi Al-Hachim MA, Central Michigan University, 2013 BS, Michigan State University, 2000 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Health Services Walden University December 2017
The Role of Biomarkers in the Diagnosis and Management of Heart Failure

Heart failure (HF) diagnosis and management remains a topic of concern across the world despite the wealth of knowledge on the heart’s pathophysiology. Around 8-12% is the risk of mortality from HF and this is still on the rise despite high end technological advancement [1]. Early diagnosis and management remains the gold standard to prevent adverse events and this is why there is a shift toward early diagnostic tools such as the biomarkers. Since current diagnostic tools are in short of sensitivity and specificity, biomarkers have gained significant attention within the last decades owing to their strength in early diagnosis, risk stratification, high sensitivity and specificity and disease progression in patients with HF [2,3]. In order for biomarkers to be used in current practice, they should show severity of ongoing disease and response to treatment to be able to tailor treatment for every individual. This article will offer a brief overview of the role of the biomarkers in the management of heart failure.
Plasma concentration of presepsin and its relationship to the diagnosis of infections in multiple trauma patients admitted to intensive care

Background and aims: Septic complications represent the predominant cause of late death in poly-trauma patients. The necessity to differentiate septic from non septic patients is more relevant at the early stage of the illness in order to improve the clinical outcome and to reduce the mortality. The identification of a sensitive and specific, clinically reliable, biomarker capable to early recognize incoming septic complications in trauma patients whose expression is not influenced by concomitant traumatic injuries, is still a challenge for the researchers in the field. Materials and method s: A retrospective analysis on 48 adult patients (9 females and 39 males, mean age 47.6±19 years) with multiple trauma was performed. The inclusion criterion was to suffer from acute trauma since no more than 24 hours and the exclusion criteria were the following: antibiotic treatment on admission and maintained for more than 48 hours; on-going infection on admission not associated with trauma; treatment with immunosuppressors/ immunomodulants; age <18 years old. Presepsin was measured using an automated chemiluminescence analyser at 1, 3, 5 and 8 days post of hospitalization. The diagnosis of systemic inflammatory response syndrome (SIRS)/infection was established according to the criteria of the Surviving Sepsis Campaign. Results and conclusions: In patients with SIRS, the mean presepsin concentration was 917,08 (±69.042) ng/L vs 980,258 (±1951.32) ng/L in patients without SIRS (P=0.769). In the infected patients, the mean presepsin concentration was 1513.25 (±2296.54) ng/L vs 654.21 (±511,068) ng/L (P<0.05) calculated among the non infected upon admission. The plasma presepsin concentration increased progressively during the first 8 days of hospitalization. Presepsin concentration in the infected patients was significantly higher than in non-infected patients. On the other hands no significant differences were found in the plasma level of presepsin among patients with and without SIRS. Any other clinical condition related to the trauma did not affect presepsin. Our data clearly suggest that presepsin may be considered an helpful diagnostic tool to early diagnose sepsis in trauma patients.
Screening for asymptomatic bacteriuria during pregnancy

Introduction: UTIs are the most common bacterial infection during pregnancy. Asymptomatic bacteriuria is common in women due to short urethra and close proximity of perineum to the anal region. It is more common in elderly patients and in pregnancy due to progestrone effect in addition to different morphological and physiological changes during pregnancy. Detection of ASB in antenatal women is important, as, undetected and evaluated ASB may lead to symptomatic infection during pregnancy, acute pyelonephritis, postpartum UTI, anaemia, preterm labour, LBW, perinatal death of the fetus. Urine culture is the gold standard screening technique for ASB during pregnancy. Aims and Objectives: To find out the prevalence of ASB in pregnant women and to find the pattern of causative organism. Material and Methods: A total of 500 pregnant women aged between 18 to 35 years were studied over a period of 1 and 1/2 years at GMC, Amritsar. Clean midstream urine samples were collected into a sterile container and then subjected to culture method. Results: Out of the 500 pregnant women, 78 (15.6%) had significant bacteriuria. High percentage of ASB was seen in 2 nd trimester (52.56%). ( E. coli ) (53.8%) was the most common organism followed by Staphylococcus aureus (17.9%). Conclusion: ASB is not uncommon in antenatal patients. All pregnant women should be screened by urine culture to detect ASB at their first visit to prevent overt UTI and other complications in both mother and fetus.
Potassium Deficiency Influences Soybean Seed Mineral Compositions and Metabolic Profiles across CO2

Impacts of potassium (K) deficiency and elevated carbon dioxide (eCO2) on seed constituents have rarely been explored in most crops including soybean. A controlled environment experiment was conducted with soybean grown under a sufficient (5.0 mM) and two deficient (0.50 and 0.02 mM) levels of K fertilization at ambient (aCO2) and eCO2 (400 and 800 μmol·mol-1, respectively). Both treatments significantly affected several constituents, with the K deficiency having stronger impacts than eCO2. Out of 49 seed constituents, K deficiency and eCO2 influenced 41 and 16 constituents, respectively. The K deficiency primarily decreased on average 16 constituents including minerals (e.g., K, P, Mg, Mn, Zn, Fe, B), oil, and essential fatty acids (e.g., linoleic and linolenic acids) but enhanced 25 constituents such as protein, amino acids, simple sugars, and stress-responsive metabolites (e.g., sugar alcohols mannitol and myo-inositol and proline). An accumulation of N while decreased C concentration resulted in the lower C:N ratio in the seeds of K-deficient plants. However, protein:oil, C:K, N:P, and N:K ratios were consistently greater under K deficiency. The eCO2 also decreased minerals such as P, S, Zn, B, and essential fatty acids but enhanced the concentration of six constituents including alanine, oleic acid, fructose, and sugar alcohols across K fertilization. In addition, the impact of eCO2 on several amino acids appeared to be dependent on the severity of K deficiency. For instance, eCO2 decreased essential amino acids (e.g., valine, phenylalanine, isoleucine) in the seeds of severely K-deficient plants but not in the other treatments leading to a K × CO2 interaction. Results showed that CO2 enrichment is likely to exacerbate the decline in the concentration of seed minerals such as P, K, S, Zn and B, essential fatty acids, and amino acids under K limited conditions.
Lactoferrin Association with Maternal Nutritional Status and Lactation Stages

Background: Previous research has not been consistently found that Lactoferrin (LF) is influenced by maternal factors, during pregnancy and postpartum. In Indonesia, the effect of mother's nutritional status to their milk quality has rarely been studied. Objective: This study aimed to determine how the mother’s nutritional status during pregnancy and the lactation period is associated with LF. Methods: This cross sectional study was performed from September to November 2017 at three primary health care centres working area in Semarang, Indonesia. Seventy-nine lactating mothers were recruited. LF was analysed from about 5 ml of human milk. Data on the mother’s general characteristics and anthropometry (weight, height, and mid-upperarm-circumference (MUAC)) were collected. Results: Mother’s average age was 28±5 years old, mostly multipara and non-working. Average haemoglobin concentration at the third trimester pregnancy was 11.3±1.09 mg/dL MUAC at the third trimester pregnancy and postpartum was 25 cm and 26.4 cm, respectively. Body mass index at postpartum was 23.74 kg/m2. Median human milk LF was 1.52 g/L. Milk was collected from mothers with ten-day-old infants (median), at 10.00 a.m. and stored 73 days before analysed. Median LF in colostrum (1.60 g/L) did not differ significantly from transition (1.99 g/L), but did with mature milk (1.07 g/L). Conclusion: Better nutritional statuses of mothers during pregnancy (as indicated by MUAC) and early stages of lactation resulted in significantly higher LF concentration in human milk. Current Research in Nutrition and Food Science www.foodandnutritionjournal. org ISSN: 2347-467X, Vol. 08, No. (1) 2020, Pg. 174-181 CONTACT Mohammad Zen Rahfiludin rahfiludinzen@gmail.com Department of Public Health Nutrition, Faculty of Public Health, Diponegoro University, Semarang, Indonesia. © 2020 The Author(s). Published by Enviro Research Publishers. This is an Open Access article licensed under a Creative Commons license: Attribution 4.0 International (CC-BY). Doi: http://dx.doi. org/10.12944/CRNFSJ.8. 1.16 Article History Received: 28 October 2019 Accepted: 20 December 2019
Clustering 16S rRNA for OTU prediction: A similarity based method

To study the phylogeny and taxonomy of samples from complex environments Next-generation sequencing (NGS)-based 16S rRNA sequencing , which has been successfully used jointly with the PCR amplification and NGS technology. First step for many downstream analyses is clustering 16S rRNA sequences into operational taxonomic units (OTUs). Heuristic clustering is one of the most widely employed approaches for generating OTUs in which one or more seed sequences to represent each cluster are selected. In this work we chose five random seeds for each cluster from a genes library, and we present a novel distance measure to cluster bacteria in the sample. Artificially created sets of 16S rRNA genes selected from databases are successfully clustered with more than %98 accuracy, sensitivity, and specificity.
Medication on the Base of Repeated Game Theory

Hypertension is offered as a major problem of curative healthful in the world. On the following of affliction to Hypertension, sufficient control of it has special validity; one of them is pharmacotherapy in this research, repeated game theory model based decision making used for finding of optimum strategy of antihypertensive medication during one year. B-blockers are choice prescription for control of blood pressure in hypertensive patients. But increase in blood lipid level must be considered as a side effect of b-blockers. All needed information of patients gathered from pubmed articles from 1979 to 2005. These models evaluated between atenolol (100mg/day) and propranolol (160mg/day) for two continuous using periods. For modeling we used of patients information at three different time interval (3, 6 and 12 months) after treatment onset. To analyze the game we determine the equilibrium points. On the base repeated game, we propose consumption of atenolol for three month and then use of a propranolol as a b-blocker for reminder of one year as an optimum strategy of blood pressure control with lowest side effect.