Miracle-dz/UniFAR-FTUs huggingface dataset:
Nitric oxide releases Cl− from acidic organelles in retinal amacrine cells

Determining the factors regulating cytosolic Cl− in neurons is fundamental to our understanding of the function of GABA- and glycinergic synapses. This is because the Cl− distribution across the postsynaptic plasma membrane determines the sign and strength of postsynaptic voltage responses. We have previously demonstrated that nitric oxide (NO) releases Cl− into the cytosol from an internal compartment in both retinal amacrine cells and hippocampal neurons. Furthermore, we have shown that the increase in cytosolic Cl− is dependent upon a decrease in cytosolic pH. Here, our goals were to confirm the compartmental nature of the internal Cl− store and to test the hypothesis that Cl− is being released from acidic organelles (AO) such as the Golgi, endosomes or lysosomes. To achieve this, we made whole cell voltage clamp recordings from cultured chick retinal amacrine cells and used GABA-gated currents to track changes in cytosolic Cl−. Our results demonstrate that intact internal proton gradients are required for the NO-dependent release of internal Cl−. Furthermore, we demonstrate that increasing the pH of AO leads to release of Cl− into the cytosol. Intriguingly, the elevation of organellar pH results in a reversal in the effects of NO. These results demonstrate that cytosolic Cl− is closely linked to the regulation and maintenance of organellar pH and provide evidence that acidic compartments are the target of NO.
Traitement de l’hallux valgus par mini-chevron : résultats cliniques et radiologiques à 5,6 ans de recul

Introduction : parmi plus de 150 techniques chirurgicales du traitement de l’hallux valgus, la chirurgie mini invasive s’est introduite en France depuis les annees 2000 et semble etre un bon compromis a la chirurgie conventionnelle « open », ou per cutanee qui demande une maitrise notable et qui n’est pas denuee d’une courbe d’apprentissage importante pour atteindre de bons resultats. Le but de notre etude est de decrire la technique du mini-chevron associee a l’osteotomie d’Akin et d’en analyser les resultats cliniques et radiographiques a 5,6ans de recul moyen. Materiel et methode : il s’agissait d’une etude retrospective monocentrique de patients operes entre janvier 2008 et decembre 2015 d’un hallux valgus isole par technique du mini chevron par 6 chirurgiens du CHU de Bordeaux. L’âge moyen des patients etait de 54ans [16-79]. Les donnees ont ete recueillies de facon prospective durant l’annee post operatoire par le chirurgien referent, et les patients ont ete revus en consultation entre juin et aout 2018 par un examinateur independant pour l’analyse au dernier recul. L’analyse etait clinique (AOFAS, douleur, mobilites articulaires, complications, recidive, satisfaction) et radiographique (Inter Metatarsal Angle IMA, Hallux Valgus Angle HVA, et arthrose). Resultats : 116 patients (139 pieds, 95% femmes) ont ete operes d’un hallux valgus et ont eu un suivi minimal d’un an post operatoire, et 60 patients (74pieds) ont ete revus au dernier recul. Le score AOFAS pre operatoire 66,35 +/- 7,4 [47-85] a ete ameliore a 1an de 28,63 points (p<0,001) avec un resultat stable au dernier recul. L’AOFAS douleur etait en pre operatoire de 26,8 +/- 6, de 38 +/- 4 a 1an et 39 +/- 3,4 au dernier recul (p<0,001). La mobilite articulaire globale s’est vue reduire a 1an de 96,5° +/- 16,7° a 89,5° +/- 17° (p=0,0005) mais s’est amelioree au dernier recul a 103,8° +/- 16,9° (p=0,003). L’IMA pre operatoire etait de 13,4 ° +/- 2,9° [5-23], 7,7° +/- 2,1° [4-14] (p<0,001) a un an et de 7° +/-2,7° [3-16] au dernier recul (p<0,001). L’HVA pre operatoire etait de 29,3° +/- 7,1°[9-50], de 12,4° +/- 3,5° [5-24] a un an (p<0,001) et de 12,9° +/- 5,2° [2-30] (p<0,001) au dernier recul. Le taux de complications etait 27% a un an (45% de vis genante et AMO) et 23% au dernier recul (64,7% de metatarsalgies ou deformations O2). Une decompensation arthrosique est apparue dans 8,1% des cas (6pieds) et une recidive a ete constatee dans 5,4% des cas (4pieds). Le score de satisfaction etait en moyenne de 8.9/10 points avec 91% de patients satisfaits. Conclusion : le traitement de l’hallux valgus par mini Chevron est une technique simple, reproductible, efficace avec une amelioration significative de la qualite de vie des patients, fiable dans le temps, qui apporte une satisfaction importante, avec taux de complications acceptable. Il s’agit donc d’un veritable outil performant dans la chirurgie de l’hallux valgus.
Somatic Symptoms in Depression

Aim : The goal of the present research was to observe somatic symptoms in cases who were experiencing severe bouts of depressions. Place and Duration Of Study: The following examination was carried out in August 2018 in Lahore. Materials and Methods: Newly diagnosed cases of depression were included. Exclusion criteria were cases experiencing some other mental ailment or physical condition, minors or those declining assent.In stage 1, clinical evaluation was completed by following ICD-10 criteria and the Urdu adaption of Beck Depression Inventory-2(BD-2) was introduced. The exhibited complaints were observed in the second stage. In the event, if more than one physical side effect is observed, it is recorded alongsidethe statistic points. The record was observed by SPSS v 21. Results: Out of the aggregate 300 cases, 187 (62.33%) showed somatic symptoms as chief complaint. The case has one or more somatic symptoms. Patients with each somatic symptom were tallied and checked and added to the aggregate rundown of symptoms. Headache was widely recognized manifestation 235(39.16%). Muscle torment as indication was accounted for by 52 (8.66%). Another common symptom that was reported was generalized weakness influences 64(10.66%). 34(5.6%) patients showed gastrointestinal unsettling and 84 (14%) had burning. Loss of appetite was evident in 52 (8.66%) patients. Different side effects were accounted for 34(5.6%). Conclusion: It very well may be inferred that larger part of the patients of depression visiting the hospitals were young married women, belonging to the lower and middle class of the society, who were little or not educated at all. 187 (62.33%) showed somatic symptoms as chief complaint. Headache 235(39.16%) was commonly found among them. Keywords: Somatic symptoms, physical symptoms, teaching hospital, depression
A novel design method for Blass matrix beam-forming networks

A novel design method for lossy Blass matrix beam-forming networks is presented. Compared to those formerly developed (W.R. Jones and E.C. DuFort, 1971), (S. Mosca et al., 2002), the new method allows the design of such circuits to generate an arbitrary number of simultaneous beams oriented in arbitrary positions. This is obtained by means of an equivalent circuit approach to compute the transmission parameters of the Blass matrix. The method has been applied to the design of a specific multi-beam waveguide application, which required the development and characterization of a novel waveguide cross coupler. Experimental results confirm the accuracy of the method showing high performance for all beams in terms of beam position, side lobe level and efficiency.
Packet Synchronization Structure with Peak Detection Algorithm for MB-OFDM UWB

In multi-band orthogonal frequency division multiplexing (MB-OFDM) wireless personal area networks (WPAN) system, a robust signal detection algorithm is required for practical hardware implementation. In the literature, the signal detection algorithms for OFDM are based on correlating the received signal with a time delayed replica of itself. The result of correlation is then compared with a threshold value. The selection of the threshold value is very important for correct packet detection. Because of the characteristics of the channel environment, the determination of a threshold value is not a trivial task. In this paper, a structure for packet synchronization in MB-OFDM is designed which has a peak detector. In this case, the determination of the threshold value is eliminated by finding the peak values of the correlation value using our proposed algorithm
Shift in the Suburbs: An Analysis of Changing Vote Patterns in American Suburbs, 2000-2018

In the 2016 Presidential Election, the movement of well-off, highly-educated suburbs towards the Democratic Party was one of the most significant yet undercovered stories. In this paper, I analyze the political changes in suburbs around five major cities (Boston, Charleston (SC), Cleveland, Los Angeles, and Minneapolis) both in 2016 and in elections dating back to 2000. I find that between 2000 and 2014, municipalities close to core cities with high percentages of college graduates became slightly but significantly more Democratic, with much of this movement taking place around 2004 and 2006. Comparing 2016 to previous elections, I find that proximity to urban areas was indeed more significant than it was in the past, but much of the change in suburban areas can simply be traced to college educated voters becoming dramatically more Democratic. Analysis of opinion data from the American National Election Studies (ANES) and the Cooperative Congressional Election Study (CCES) suggests that this movement is likely due to a combination of liberalizing attitudes on social issues like abortion and a perception of the Republican Party moving to the right on racial issues. While early analysis of data from the 2018 Midterm Elections points to the durability of the suburban shift, it remains too early to determine whether 2016 really marked the beginning of a long-term political realignment in the suburbs.
Interference based Call Admission Control for Wireless Ad Hoc Networks

In this paper, we propose a call admission control mechanism for wireless ad hoc networks called interference-based call admission control (iCAC). iCAC is unique in that it does not treat interference uniformly instead classifies interference based on estimates of the position of the interfering nodes. iCAC relies on two novel techniques: (1) estimation of position of the interfering nodes (2) fair allocation using bandwidth acquisition and rate control. By incorporating these techniques, iCAC is able to increase the estimated available bandwidth substantially without overloading the network. We compare iCAC with perceptive admission control (PAC) and IEEE 802.11 without admission control. Simulation results show that iCAC is able to admit substantially more requests than PAC, achieves more than 80% of the throughput of IEEE 802.11 and at the same time maintains very low packet loss rate and average delay comparable to PAC
Application of Model Predictive Control for active load management in a distributed power system with high wind penetration

Summary form only given. This paper introduces an experimental platform (SYSLAB) for the research on advanced control and power system communication in distributed power systems and one of its components-an intelligent office building (PowerFlexHouse), which is used to investigate the technical potential for active load management. It also presents in detail how to implement a thermal Model Predictive Controller (MPC) for the heaters' power consumption prediction in the PowerFlexHouse. It demonstrates that this MPC strategy can realize load shifting, and using good predictions in MPC-based control, a better matching of demand and supply can be achieved. With this demand side control study, it is expected that MPC strategy for active load management can dramatically raise energy efficiency and improve grid reliability, when there is a high penetration of intermittent energy resources in the power system.
A review on innovations in polymeric nanocomposite packaging materials and electrical sensors for food and agriculture

ABSTRACT The application of polymer nanocomposites packaging materials in industrial, food and agricultural products is a superior alternative to traditional packaging materials such as glass, paper, and metals due to their functionalization, flexibility, and minimal cost. However, usage of these materials has been hindered due to their inferior mechanical and barrier behaviors, which are susceptible to improvement through inclusion of functionalized reinforcing macro- or nanoﬁllers. Furthermore, most reinforced materials exhibit inferior matrix–ﬁller interfacial interactions, which are enhanced with reducing ﬁller dimensions. Hence, this review elucidates functionalization of composites interfacial interaction and its relationship to enhancement of the properties of packaging materials, especially antimicrobial tendencies, enzyme immobilization behavior, biosensing affinity, and so on. Thus, a fundamental understanding of interfacial structure and its relationship to the overall improvement of properties are presented. Therefore, nanomaterials, such as cellulose, nanoclay, halloysite nanotubes, carbon allotropes (graphene and carbon nanotubes), silica, and so on, are discussed relative to their surface treatment approaches and effects on composites films properties for effective packaging. Recently, emerging innovations in nanostructured polymeric composite materials and electrical-sensors, their current applications and future outlook as food, agricultural and industrial packaging materials are also herewith elucidated. Graphical Abstract
An SBL-Based Coherent Source Localization Method Using Virtual Array Output

Direction of arrival (DOA) estimation as a fundamental issue in array signal processing has been extensively studied for many applications in military and civilian fields. Many DOA estimation algorithms have been developed for different application scenarios such as low signalto-noise ratio (SNR), limited snapshots, etc. However, there are still some practical problems that make DOA estimation very difficult. One of them is the correlation between sources. In this paper, we develop a sparsity-based method to estimate the DOA of coherent signals with sparse linear array (SLA). We adopt the off-grid signal model and solve the DOA estimation problem in the sparse Bayesian learning (SBL) framework. By considering the SLA as a ‘missing sensor’ ULA, our proposed method treats the output of the SLA as a partial output of the corresponding virtual uniform linear array (ULA) to make full use of the expanded aperture character of the SLA. Then we employ the expectation-maximization (EM) method to update the hyper-parameters and the output of the virtual ULA in an iterative manner. Numerical results demonstrate that the proposed method has a better performance in correlated signal scenarios than the reference methods in comparison, confirming the advantage of exploiting the extended aperture feature of the SLA. key words: direction of arrival (DOA) estimation, off-grid model, sparse Bayesian learning (SBL), sparse signal recovery (SSR), coherent source
Long-Term Treatment Outcomes after Intravascular Ultrasound Evaluation and Stent Placement for Atherosclerotic Subclavian Artery Obstructive Lesions

The objective of this study was to determine long-term outcomes after stent placement for subclavian artery (SA) obstructive lesions assisted by intraoperative intravascular ultrasound (IVUS). The study included 25 lesions in 24 patients who underwent stent placement assisted by intraoperative IVUS for subclavian artery stenosis or obstruction at our hospital between January 2003 and August 2010. Outcome was evaluated based on the results within 30 postoperative days (technical success rate, improvement in upper extremity ischemia, steal syndrome, left-right blood pressure difference, and perioperative complications) and the results after 30 postoperative days (incidence of vertebrobasilar artery territory infarction and restenosis). Stent placement and vessel dilatation were successful in all patients, without perioperative complications. Upper extremity ischemia, steal syndrome, and left-right blood pressure difference disappeared in all cases. During follow-up observation (6–96 months; median 51 months), no restenosis occurred at the stent placement site in any patient. In one case, four years after initial treatment, stenosis was noted proximal to the stent placement site. Satisfactory long-term as well as short-term outcomes were achieved after stent placement for SA obstructive lesions assisted by intraoperative IVUS evaluation.
Conversion of a kerosene-fuelled gas turbine to run on propane.

This study forms part of a greater research objective to use air as a heat transfer fluid, and a combined gas and steam cycle in a concentrated solar power plant. Combustion will be used to compensate for solar fluctuations. The conversion of a Rover 1S/60 gas turbine to run on propane was completed in this study. In a previous study, the Rover gas turbine was run on jet fuel with standard hardware, before being converted to run on LPG at low speed. In this study, the fuel control system was improved for easier throttle control, and for a higher fuel consumption rate. The gas turbine was successfully run on propane at full speed and 77 % of rated power, which is close to the performance previously achieved with jet fuel (88 % of rated power). The power output was constrained by the exhaust gas temperature (EGT) limit. According to the engine specifications, the power produced with jet fuel and propane was low compared to the EGT and fuel consumption. A few external factors were considered, but the condition of the gas turbine was considered to be the primary cause. Besides this limitation, the conversion was considered a success, and the gas turbine ran well on propane. A general method for the conversion of a gas turbine from liquid to gaseous fuel was proposed. The method was used to review the conversion of the Rover gas turbine. The conversion was satisfactory within the project scope. The fuel control system requires manual operation and steady load, which was suitable for engine testing. The system could be automated for a broader range of application. For example, in a concentrated solar power plant. A CFD model was used to compare the cold (non-reacting) flow of the combustion chamber (combustor) with the original liquid atomiser to that with the custom gas injector. The model indicates that the conversion has resulted in significantly different flow, which could affect the flame tube cooling. Without any apparent benefit from the change in flow, it is recommended to modify the gas injector to match the combustor flow with the original atomiser. iv Stellenbosch University https://scholar.sun.ac.za
ASSESSMENT THE SYNCHRONY BETWEEN UTERINE STATUS AND HORMONAL PROFILES IN MODIFIED OVSYNC PROTOCOLS IN RELATION TO FERTILITY IN BUFFALOES

A total of 36 pluriparous buffaloes were used to study the uterine morphometry in response to serum estradiol concentrations and associated estrogen receptors (ERs) expression in modified ovsync protocols. The buffaloes were assigned to St-ovsync, CIDR-sync and Insulin- sync (n=12 for each). The St-ovsync consisted of two IM injections of 20µg buserelin on the Day 0 (GnRH1) and on the Day 9 (GnRH2) and an IM injection of 500 µg of cloprostenol sodium (Estrumate) on the Day 7. Buffaloes in CIDR-sync and Insulin-sync protocols were treated as in the St-Ovsync protocol in addition to intravaginal insertion of CIDR from the Day 0 to 7 in case CIDR-sync and SC injection of Insulin at a dose of 0.25 lu/kg on the Days 7, 8 and 9 in Insulin-sync. Blood samples were collected and the uterine wall thickness (UWT) was simultaneously measured by transrectal ultrasonography on the Days 0, 3, 5, 7, 8 and 9. Endometrial biopsy samples were collected from five buffaloes per group for quantifying the abundance of estrogen receptors. The UWT on the Days 3 and 5 showed a decrease (p<0.05) while the serum p4 concentration on the Day 3 showed an increase (p<0.05) in eventually diagnosed pregnant (EDP) buffaloes in CIDR-sync compared with their counterparts in either St-Ovsync or Insulin-sync. On the Day 9, although there was a decrease in the serum E2 concentration in CIDR-sync compared with either St-Ovsync or Insulin-sync in EDP buffaloes, there was an increase (p<0.05) in the ER mRNA expression in CIDR-sync compared with St-Ovsync. It could be concluded that modifying the St-Ovsync, by p4 supplementation through intravaginal insertion of CIDR from the Day 0 to 7 or by SC injection of insulin on the Days 7, 8 and 9, could modulate uterine morphometry such conductive to proper fertility response. Key words : Erα; uterine wall thickness; Ovsync
Harmonic Interaction Analysis in a Grid-Connected Converter Using Harmonic State-Space (HSS) Modeling

An increasing number of power-electronic-based distributed generation systems and loads generate not only characteristic harmonics but also unexpected harmonics. Several methods, such as impedance-based analysis, which are derived from the conventional average model, are introduced to perform research about the harmonic interaction. However, it is found that the linear-time-invariant-based model analysis makes it difficult to analyze these phenomena because of the time-varying properties of the power-electronic-based systems. This paper investigates a grid-connected converter by using the harmonic state-space (HSS) small-signal model, which is based on a linear time-varying periodically theory. The proposed model can include the switching behavior of the model, where it makes the model possible to analyze how harmonics are transferred into both the ac-side and dc-side circuits. Furthermore, a harmonic matrix of the grid-connected converter is developed to analyze the harmonic interaction at the steady-state behavior. Besides, the frequency-domain results are compared with time-domain simulation results by using the HSS modeling to verify the theoretical analysis. Experimental results are finally discussed to verify the proposed model and study.
PENGARUH WORKPLACE INCIVILITY DAN JOB BURNOUT TERHADAP TURNOVER INTENTION PADA CV METALIK BARU

Human resources in the company is an important aspect for the company, where the company has Human Resource Development (HRD) department to coordi­nate and develop existing human resources on CV Metalik. The phenomenon that occ­urs in the CV. Metalik Baru is the employee turnover rate on CV Metalik Baru is high enough to be evident from employee turnover data obtained with high turnover rate from January to December 2017. One of the factors affecting turnover intention is work­place incivility. In addition, other factors that may affect turnover intention is the job burnout. The purpose of this research is to know the influence of workplace inci­vility and job burnout partially and simultaneously toward intention turnover at CV Metalik Baru. This research uses causality research design using quantitative met­hod. Population Sample in this research is employees at CV Metalik Baru as many as 40 employees. The analytical technique used multiple linear regression. Based on the re­sults of research and discussion it can be concluded that the workplace increment and job burnout variables partially and together affect the turnover intention on the CV. Metalik Baru. Then proven H 1 , H 2, and H 3 are accepted.