Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative evaluation of performance and cost effectiveness of HiCrome UTI agar in detection of urinary tract pathogens

Urinary tract infections (UTI) are important clinical entities, making urine, the most frequent sample received for culture in clinical microbiology laboratory's daily workload. Traditionally conventional media like Blood agar (BA) and MacConkey agar (MAC) are being used in combination by most of the laboratories in developing countries. Moreover, they are unsuitable as an ideal primary isolation medium and chromogenic agar medium like HiCrome UTI Agar is a differential medium recommended for it. The present study was undertaken to validate the usefulness of HiCrome UTI agar as a primary urine culture medium for its rate of isolation and presumptive identification of uropathogens in comparison to BA and MAC Agar in a Nair Hospital, in Mumbai. Patients included were randomly selected 3300 subjects who were married pregnant and non-pregnant women reporting to ANC clinic of the hospital of age group of 18 to 40 years. Collection, Transportation, Processing of urine, microscopic examination and Urine culture was carried out by standard methods. HiChrome UTI agar, BA and MAC agar were used simultaneously. Antibiotic sensitivity testing of test isolates (200 gram negative and 52 gram positive) bacteria were done, which were separately collected from Hichrome UTI, BA and MAC agar, to check the susceptibility pattern of isolates, isolated from different agar. Both HiCrome UTI agar and BA supported more than 75 % bacterial growth, while MAC agar supported 52.30% growths. For presumptive identification of bacterial species, of 259 bacterial isolates, 99.40% could be differentially identified on HiCrome UTI agar against 49.0% and 81.0% on BA and MAC agar respectively. Comparative results of three culture media for their rate of isolation of polymicrobial growth of uropathogens showed that HiCrome UTI agar supported 100% bacterial growth, while BA and MAC agar supported 40% bacterial growth each. Susceptibility pattern of all the isolates collected from HiCrome UTI, BA & MAC agar was found to be similar. Cost of HiCrome UTI agar per test per urine sample was found to be less than traditional identification methods. Hence, the study shows that HiCrome UTI agar is an excellent and time saving media for the reliable identification of most of the uropathogens and differentiation of mixed bacterial cultures in primary culture plate as compared to conventional culture system.
Potential applications of Agrobacterium virulence gene promoters in plant-protecting microbial inoculants.

The concept behind this project was to continue the development of strains of Agrobacterium tumefaciens that were capable of producing pesticidal proteins in response to plant wounding, thereby killing the invading organism. To this end, vir induction was studied in A. tumefaciens and a protocol to elicit the maximum response was developed. In order for this concept to work, it was necessary to determine whether vir induction was occurring at plant wound sites and a method for showing this was developed, the results suggesting that indeed vir induction did occur. The stability of two types of plasmid was also analysed in this bacterium to ascertain how stable the proposed 'microbial inoculant' would be in the field. The results suggested that IncW plasmids should not be used in the final product. The activities of two chitinases from Serratia marcescens were analysed and it was found that both chitinases were effective in controlling some types of fungus. In addition it was found that the expression of chiB in Escherichia coli led to the appearance of a filamentous phenotype at intermediate temperatures. A construct was made that linked the virE promoter to the chiB gene. This plasmid was introduced into A. tumefaciens but did not function as expected. However, other constructs were demonstrated to be inducible although they were only partially successful in controlling the fungi that the strains were assayed against. The Bacillus thuringiensis 5-endotoxin gene, crylA(c), was cloned and various constructs were made to examine the effects of various regions of the native promoter. One constract was made that linked the virB promoter to crylA(c) and this was introduced into A. tumefaciens. The resulting strain was capable of inducible δ-endotoxin expression and was also capable of controlling the larvae of the tobacco homworm, Manduca sexta.
Transgenic animals

Transgenic animals are organisms in which permanent gene modifications have been experimentally introduced into their germline. Most knowledge of modern biology relating to the tissue-specific regulation of genes and their function in development and diseases stems from studies using transgenic mice. Transgenic technology also offers the unique opportunity for generating animal models for human diseases and for producing large quantities of biomedically important proteins in farm animals. Furthermore, the recent development of ‘gene switches’ regulating gene expression in a temporal and/or tissue-specific manner opens up new possibilities for the study of gene function in the context of the whole animal.
Sitagliptin Inhibits Extracellular Matrix Accumulation and Proliferation in Lung Fibroblasts

Background Fibroblasts activation-induced fibrosis can cause idiopathic pulmonary fibrosis (IPF). Excessive activation of fibroblasts contributes to poor healing or severe visceral fibrosis and even organ dysfunction. Sitagliptin acts as a dipeptidyl peptidase 4 inhibitor to reduce glucose level in type 2 diabetes, but its role in fibrosis of lung fibroblasts is elusive. We investigated the mechanism of sitagliptin in TGF-β-activated lung fibroblasts and evaluated the efficacy of sitagliptin in extracellular matrix accumulation and fibroblasts proliferation. Material/Methods By in vitro lung fibroblasts culture, we assessed the expression of lung fibroblasts biomarker (α-SMA) and extracellular matrix (Col-1, Col-3, fibronectin) following TGF-β stimulation and treatment with sitagliptin. Mechanistically, the phosphorylation level of Smad-3 protein in cells was analyzed using Western blotting, and the apoptosis level was assessed by Western blotting and flow cytometry. The degree of proliferation was determined using immunofluorescence and scratch-healing assay. Results We found that treatment with sitagliptin attenuates fibroblasts activation following TGF-β stimulation. Furthermore, the extracellular matrix was decreased by sitagliptin treatment by suppressing the phosphorylation level of Smad-3 protein. We found that sitagliptin does not affect apoptosis in fibroblasts, but it does affect the degree of proliferation of lung fibroblasts, thus ameliorating fibrosis after TGF-β stimulation. Conclusions Sitagliptin inhibits fibrosis in TGF-β-induced lung fibroblasts activation, which restrains extracellular matrix formation and cell proliferation in fibroblasts. Therefore, sitagliptin appears to have promise as a treatment of fibroproliferative disease caused by activation and proliferation of fibroblasts.
The ecology of and fishery for Coryphaena spp. in the waters around Australia and New Zealand

Two species of dolphinfish, Coryphaena hippurus and Coryphaena equiselis , are found in Australian waters and off the north-eastern coast of New Zealand. Both species (also called Mahi-mahi, or dorado) are generally found in tropical waters, but only C. hippurus is captured in southern waters (to 34°S). Dolphinfish are caught by recreational and commercial fishers, using either trolled or baited lines. Most catch records do not allow the identification of fish to the species level. Dolphinfish are also an incidental catch of foreign and domestic pelagic fisheries (e.g. long-lining for tunas and billfishes) and 10-70 tonnes are taken per year in the Australia-New Zealand region. Although Coryphaena are known to associate with objects (e.g. traps for carangids and navigation buoys) and are a focus for recreational fishers, Fish Attraction Devices (FADs) are not used by commercial fishers off the coast of Australia and New Zealand. FADs are, however, used by fishers in the Pacific Islands. Recreational catches of Coryphaena may exceed the commercial catch in some areas. Good data for New South Wales, Australia, gave estimates of 11.7 and 12.7 tonnes of Coryphaena caught in 1994 and 1995 respectively, which represented 1.1-1.8x the recorded commercial catch. Approximately ~12,600 fish have been tagged since 1973 around Australia and data on returns are only available for 108 fish (0.86% recovery). Tagged Coryphaena were found to move distances of up to 440 kilometres and at estimated speeds of up to 20 kilometres per day. The time between tag and recapture varied from 0-360 days and fish moved 0-440 kilometres. The majority of fish were caught around the same drifting object near where they were tagged. The collection of Coryphaena larvae in Queensland and New South Wales, along the east coast of Australia, indicates spawning in these waters. Most larvae have been collected in the austral summer and autumn and typically in surface waters well offshore. Dolphinfish have been successfully raised from eggs to fish of marketable size in Western Australia and the species appears to be an excellent candidate for mass production, which is now possible in Australia.
Spindle assembly checkpoint satisfaction occurs via end-on but not lateral attachments under tension

and tension at individual mammalian kinetochores. We show that Mad1 loss from the kinetochore is switch-like with robust kinetics and that tension across sister kinetochores is established just before Mad1 loss events at the first sister. We demonstrate that CenpE-mediated lateral attachment of the second sister can persistently generate this metaphase-like tension before biorientation, likely stabilizing sister end-on attachment, yet cannot induce Mad1 loss from that kinetochore. Instead, Mad1 loss begins after several end-on microtubules attach. Thus, end-on attachment provides geometry-specific molecular cues or force on specific kinetochore linkages that other attachment ge-ometries cannot provide.
ANALYSIS OF THE IMPACT OF INVESTMENT TO SOCIAL ACTIVITIES ON THE COMPANY ‘S FINANCIAL PERFORMANCE

This study operationalizes corporate sustainable development, explains what socially responsible investment is. The main issue of work is to analyse "Vodafone's" different branches investment (Spain, Portugal, Italy, Greece) to sustainable development and how does it affect corporation financial performance. To achieve this goal for analyses correlation methodology is used. Data collected from annual sustainable responsibility and financial reports using two measurements – the amount of investment to social projects (EUR), and EBITDA margin. Research range is 2011-2017. Calculations are made using excel. It is found that investments to social projects differently affects a company's financial performance, Italy and Portugal relationship between investment and EBIDTA make a positive impact.
[Mourning].

A PAINFUL EXPERIENCE: Mourning characterizes the grief of a person who has lost a loved one forever. The bereavement that follows is natural and should not be medicated. Mourning is not a disease; it is one of the most painful facts of life. In fact, the more we are attached to someone, the more we will suffer his or her loss. This is unavoidable. The grief expressing our attachment is accompanied by immediate and intense regression with repeated need for consolation. For some people, it can be the means of coming to terms with their own mortality. THE STAGES OF MOURNING: There are several stages of mourning: the living person's ambivalence toward the deceased, the recollection corresponding to the progressive acceptance of the loss, which represents the first phase of the mourning process. During the healing phase, the mourner is gradually capable of recalling the good times during the life of the deceased and then progressively of evacuating the souvenirs and start living and opening up to others again. COMPLICATED MOURNING: Mourning may be passionate and characterized by the refusal to integrate the loss, or delayed, with an apparent lack of grief and sorrow. Chronic depression is a sort of greater degree of severity compared with delayed mourning. A denial mechanism installs: the loved one is not dead and will return. A split in personality can be observed: part of the person will integrate the reality; the other will retreat from it. In this case, recollection will not lead to integration of the loss. Somatization disorders or organic problems can be observed and more rarely grief melancholia, mania, hysteria or obsessional grief. These are the domain of the specialist. GENERAL PRINCIPLES FOR THE PHYSICIAN: Reality is always preferable to imagination. Listening to the patient must precede any medication. In severe cases of grief, sedative antidepressors are preferable and the co-prescription of anxiolytics, particularly benzodiazepines should be avoided. One should not hesitate to seek advice from a specialist.
Effect of Surface Roughness on Pool Boiling Heat Transfer Coefficient

This study aims to determine the effect of variations in surface roughness on the performance of the pool boiling heat transfer coefficient. Experiments were carried out using copper with a diameter of 30 mm polished using sandpaper with various roughness variations. Obtained the average roughness (Ra) surface of the test specimens ranged from 0,04 μm – 0,22 μm. De-ionized water are used as working fluids and experiments run at atmospheric pressure and saturation temperature. The results showed that the copper surface with an average roughness (Ra ) of 0,22 μm had the best pool boiling performance marked by the highest heat transfer coefficient. In addition, the specimens with an average surface roughness of 0,22 μm have the highest bubble nucleation site compared to other specimens. Abstrak. Penelitian ini bertujuan untuk mengetahui pengaruh variasi kekasaran permukaan pada unjuk kerja pool boiling heat transfer coefficient. Eksperimen dilakukan dengan menggunakan tembaga dengan diameter 30 mm yang dipoles menggunakan amplas dengan berbagai variasi kekasaran. Didapatkan hasil kekasaran rata – rata (Ra) permukaan benda uji berkisar 0,04 μm – 0,22 μm. Aquades digunakan sebagai fluida kerja dan eksperimen berjalan pada tekanan atsmosfer dan temperatur saturasi. Hasil penelitian menunjukkan bahwa permukaan tembaga dengan kekasaran rata-rata 0,22 μm mempunyai unjuk kerja pool boiling paling baik ditandai dengan nilai heat transfer coefficient paling tinggi. Selain itu, pada benda uji dengan kekasaran permukaan rata – rata (Ra ) 0,22 μm memiliki bubble nucleation site yang paling banyak dibandingkan dengan benda uji lainnya. Kata kunci: pool boiling, heat transfer coefficient, kekasaran permukaan. © 2019. BKSTM-Indonesia. All rights reserved
o-glassesX: Compiler Provenance Recovery with Attention Mechanism from a Short Code Fragment

Program binaries are often the focus of forensic investigations. Extracting compiler provenance is important in digital forensics, as it provides crucial information about the process by which a malware binary is produced. Object files and libraries, which are components of an executable file, are often compiled in various environments. Thus the executable file bears important information about the development environment of the authors. It is expected to reveal valuable information of the authors if we could extract those compiler provenances with high accuracy enough to resolve each component. In this paper, we investigate the feasibility of compiler identification from a very short code fragment. Surprisingly, we found that a randomly sampled code fragment consisting of only 16 sequential instructions is sufficient to identify the program provenance, such as the source compiler family and the optimization level of machine code efficiently. Additionally, our method can visualize how much each instruction contributed to the classification result. The model uses the attention mechanism, widely used in natural language processing, and CNN with a local receptive field specialized for recognition of one instruction. Moreover, our method takes both opcodes and operands as input, while many of the existing methods had omitted operands. We used a dataset that consists of 28,074 binaries developed in 19 different classes. Each class corresponds to a combination of five different compilers, two different optimization levels (none/max), and two different CPU architectures (x86/x86-64). With this dataset, our method identifies one of the 19 classes with 0.956 accuracy, which is a competitive performance with the best-known results, from only 16 instructions or an equivalent binary sequence of length 30-60 bytes. This result is satisfactory in resolving the component-wise compiler provenance of an executable binary. Additionally, the attention mechanism allows us to extract typical instructions generated by each compiler automatically. The attention mechanism is useful not only for improving the classification performance but also for understanding the characteristics of each class.
Serum Uric Acid in Preeclampsia Level of Serum Uric Acid in Pre-eclamptic and Normal Pregnant Women

Objective: The objective of study was to find out serum uric acid level in normal and preeclamptic pregnant women of third trimester visiting outpatient department of obstetrics and gynecology of Bahawal Victoria Hospital, Bahawalpur. Methodology: It was a cross sectional descriptive study conducted form July 2018 to June 2019. All primigravida women of age 18-35 years in third trimester of singleton pregnancy attending in Obstetrics and Gynecology O u t p a t i e n t Department of Bahawal Victoria Hospital in study duration were included in the study. Statistical analysis was performed by using SPSS version 14. Chi-square test was performed to find the statistical difference regarding uric acid distribution between groups and ‘p’ value <0.05 was considered as a lowest level of significance. Results: Out of total 1212 women 84.6% were normal and 15.4% had preeclampsia. In our study out of 187 preeclamptic women, 63.6% had raised serum uric acid level and out of 268 normal pregnant women uric acid level was raised in only 39.5%. Results were found statistically significant. Conclusion: Results of our study suggest that serum uric acid level in pregnant women can be used as a useful and inexpensive marker in prediction of preeclampsia and preventive measures can be taken accordingly.
Cavity dwellers (coelobites) under coral rubble in southern Belize barrier and atoll reefs

Coral rubble is the most common hard substrate on barrier and atoll reefs in southern Belize, as it is on many other reefs. Occurrence, successional patterns, colonized area and diversity of reef cavity dwellers (coelobites) living on undersides of coral rubble are different in the major reef environments. There are at least 94 species under rubble collected at 94 stations along 5 transects. Crustose coralline algae, bryozoa and polychaetes are most abundant in the deep fore reef; mollusks and non-boring sponges are most abundant in the back reef; the encrusting foraminifer Homotrema rubrum and vermetid gastropods are most abundant around the reef crest and in the shallow fore reef. Colonized area of coelobites increases seaward and is highest in the deep fore reef. Species richness and evenness are lowest at the reef crest and in the shallow fore reef and highest in the deep fore reef. Around the reef crest and in the shallow fore reef, the coelobite community is in early and intermediate stages of succession. Deep fore reef coelobite communities exhibit exclusively intermediate successional stages. In the back reef, intermediate and late stages of succession occur. Three major factors are found to control development, distribution, abundance and diversity of coelobites under rubble: (1) rubble stability, (2) flushing of sub-rubble cavities and (3) biological interactions between organisms.
Tracing power in transdisciplinary sustainability research: an exploration

While transdisciplinary (TD) sustainability research is closely tied to ideas of societal change, critical enquiries into power dynamics both within and stemming from these practices have been scant. In this article, we operationalise theories of power for an exploration of the multiple ways in which power relations pervade interactions between researchers and practitioners in these knowledge production processes. By combining theories of power over, power to and power with, we propose a set of empirical questions to systematically study both productive and repressive forms of power. Using empirical examples, we illustrate how the proposed approach makes it possible to trace power throughout TD processes: in 1. developing the project and framing the research problem, 2. co-producing knowledge, and 3. bringing results to fruition. The power perspective proposed here can guide the thinking of those actors involved in TD processes as well as meta-analyses by third parties. An enhanced understanding of the workings of power can help improve process design and facilitate reflexive TD practice.
Enabling Secure Trustworthiness Assessment and Privacy Protection in Integrating Data for Trading Person-Specific Information

With increasing adoption of cloud services in the e-market, collaboration between stakeholders is easier than ever. Consumer stakeholders demand data from various sources to analyze trends and improve customer services. Data-as-a-service enables data integration to serve the demands of data consumers. However, the data must be of good quality and trustful for accurate analysis and effective decision making. In addition, a data custodian or provider must conform to privacy policies to avoid potential penalties for privacy breaches. To address these challenges, we propose a twofold solution: 1) we present the first information entropy-based trust computation algorithm, IEB_Trust, that allows a semitrusted arbitrator to detect the covert behavior of a dishonest data provider and chooses the qualified providers for a data mashup and 2) we incorporate the Vickrey–Clarke–Groves (VCG) auction mechanism for the valuation of data providers’ attributes into the data mashup process. Experiments on real-life data demonstrate the robustness of our approach in restricting dishonest providers from participation in the data mashup and improving the efficiency in comparison to provenance-based approaches. Furthermore, we derive the monetary shares for the chosen providers from their information utility and trust scores over the differentially private release of the integrated dataset under their joint privacy requirements.