Miracle-dz/UniFAR-FTUs huggingface dataset:
Remplissage vasculaire préhospitalier en traumatologie: Hesteril® 6 % versus Plasmion®

Objectif: Evaluer la place d'un Hydroxyethylamidon (Hesteril® 6 %) de duree d'action intermediaire dans la reanimation prehospitaliere des traumatises hypovolemiques en le comparant a une gelatine fluide modifiee (Plasmion®). Type de l'etude: Prospective, multicentrique, randomisee et ouverte. Methodes: Les blesses etaient inclus s'ils avaient une PAS < 100 mmHg associee a des signes d'hypoperfusion peripherique. Ils ont recu une perfusion d'Hesteril® (groupe H) ou de Plasmion® (groupe P) pour retablir une PAS a 100 mmHg stable pendant 10 minutes dans la limite de 2000 ml. Si l'objectif etait atteint avant ce volume, l'etude etait arretee. Dans le cas contraire, un remplissage complementaire par du Plasmion®etait poursuivi dans les deux groupes et eventuellement associe a d'autres therapeutiques (pantalon antichoc, catecholamines, transfusion). Resultats: L'etude a porte sur 164 patients dont 128 per protocole (groupe H = 85, groupe P = 79). SAMU. Un volume perfuse moyen de 830 ml (groupe H = 820 ± 63 ml, groupe P = 840 ± 56 ml) a permis d'atteindre l'objectif hemodynamique en augmentant la PAS de 36 mmHg dans le groupe H et de 32 mmHg dans le groupe P au cours d'une prise en charge, en moyenne, d'une heure. Seul un nombre limite de blesses a necessite dans l'un ou l'autre groupe le recours des therapeutiques complementaires. Quatre patients dans le groupe H et 10 dans le groupe P ont recu un remplissage complementaire par Plasmion® (difference significative p = 0,078). Il y a eu 20 recours a des therapeutiques complementaires (12 dans le groupe H, 8 dans le groupe P, p = 0,27). Une baisse de l'hematocrite d'environ 10 % a ete observee dans les deux groupes. Il n'a pas ete rapporte d'effet indesirable specifique aux solutes perfuses. La mortalite initiale observee lors de la prise en charge (8 %) traduit la severite des traumatismes en rapport avec un RTS moyen tres faible [5, 6]. Conclusion: Avec un volume moyen d'environ 800 ml et dans la limite de 2000 ml, la perfusion d'Hesteril® 6 % est une alternative interessante a la perfusion de Plasmion® pour la reanimation prehospitaliere des traumatises hypovolemiques.
Physical Properties of Geopolymer Concrete Incorporating Silica Fume and Ground Granulated Blast-Furnace Slag

This research presents new matrixes geo-polymer concrete, cementing mainly on engineering properties discusses the physical properties. In addition, the study of polymer concrete on two productions. GEO-polymer concrete GGBS and SF was created. Alkaline solution were used in this study. They are sodium hydroxide, sodium silicate solution and superplasticizer. 150 mm x 150 mm x 150 mm sample cube with a size of compressive strength were put to the test. GGBS concrete compressive strength of geo-polymer age 7, 14 and 28 days were 54.17, 66 and 69 on the MPa. And compressive strength of polymer concrete SF ground tests at the age of 7, 14 and 28 days were 1.45 1.42 1.45, and the MPa. GGBS concrete geo-polymer curing time at all compressive strength showed improved results. But geopolymer concrete compressive strength of SF given. In addition, 7 and 28 days old, low permeability and GGBS was made of geopolymer concrete were tested when absorption shown.
Effect of deferasirox + erythropoietin vs erythropoietin on erythroid response in Low/Int‐1‐risk MDS patients: Results of the phase II KALLISTO trial

Erythropoiesis‐stimulating agents (ESAs) remain first‐choice to treat symptomatic anemia and delay transfusion dependence in most patients with lower‐risk myelodysplastic syndromes (MDS) without del(5q). Deferasirox increased erythroid responses in some lower‐risk MDS patients in clinical trials, and adding low‐dose deferasirox to ESA treatment may further improve erythroid response.
Evaluating willingness-to-pay thresholds for dementia caregiving interventions: application to the tailored activity program.

OBJECTIVES The study aims to apply willingness-to-pay (WTP) values derived from the literature to inform decision-makers of the cost-effectiveness of the Tailored Activity Program (TAP), an intervention proven to reduce caregiver burden. METHODS TAP and other caregiver interventions employ an individual perspective and non-quality-adjusted life-year (QALY) outcome measure where the primary objective is to determine caregiver burden from an individual perspective. Therefore, standard cost/QALY thresholds are not appropriate. To identify relevant WTP values, we searched for studies that: 1) were published in the past 5 years and used contingent valuation methodology to identify WTP; 2) assessed WTP for a dementia-related intervention requiring out-of-pocket expenditure; and 3) asked caregivers their WTP for an outcome related to reducing caregiver burden. Three studies were identified utilizing four WTP values. We also assessed potential financial savings that caregivers could achieve from purchasing TAP. To assess the probability of TAP being cost-effective, we built a Monte Carlo simulation to test the four WTP values applied to two TAP outcome measures: reduction in caregiver hours "on duty;" and "doing things. " RESULTS For outcome measure "on duty," WTP varied between $1.06/hour and $4.58/hour. For outcome measure "doing things," WTP varied between $2.21/hour and $9.57/hour. Applying the four identified WTP values from the literature to TAP outcomes resulted in TAP cost-effectiveness varying between 50% and 80% for both outcome measures. CONCLUSIONS When WTP data are not collected prospectively or conventional metrics cannot be applied, retrospectively assessing literature-derived WTP may be acceptable for informing decision-makers of potential cost-effectiveness of a proven program. Application of WTP to TAP shows potential cost-effectiveness that can be expected under the tested WTP scenarios.
Hybrid Cloud System and Software Agent: Towards Hybrid Cloud Intelligent Agent System

Clouds are used through a service-oriented interface that implements the 'as-a-service' paradigm to offer cloud services on demand. The adaptation of cloud users and clouds services and application needs required large-scale infrastructures for high-performance computing, since this could be provided only by cloud computing. This paper discusses the cloud computing models, services and architectures. Specifically, discusses the differences and potential synergies between hybrid cloud computing models and Multi Agent Systems (MASs). The main contribution of this paper is to highlight the challenges of using intelligent software agent in high performance complex hybrid cloud computing models. The convergence of interests between MASs that need reliable distributed infrastructures and cloud computing systems that need intelligent software with flexible, dynamic and autonomous behavior can result in new systems and applications.
Multiple-window Bag of Features for Road Environment Recognition

The idea of Bag of Features (BoF) is recently often employed for general object recognition. But, as it does not take positional relations of detected features into account, the recognition rate is still not very high for practical use. This paper proposes a method of describing the feature of an object by the BoF representation which considers positional information of the features. Although the original BoF representation is applied to an entire image, the proposed method employs multiple windows on an image. The BoF representation is applied to each of the windows to represent an object in the image interested for recognition. The performance of the proposed method is shown experimentally.
Tidal Modulation of Ice-shelf Flow: a Viscous Model of the Ross Ice Shelf

Three stations near the calving front of the Ross Ice Shelf, Antarctica, recorded GPS data through a full spring-neap tidal cycle in November 2005. The data revealed a diurnal horizontal motion that varied both along and transverse to the long-term average velocity direction, similar to tidal signals observed in other ice shelves and ice streams. Based on its periodicity, it was hypothesized that the signal represents a flow response of the Ross Ice Shelf to the diurnal tides of the Ross Sea. To assess the influence of the tide on the ice-shelf motion, two hypotheses were developed. The first addressed the direct response of the ice shelf to tidal forcing, such as forces due to sea-surface slopes or forces due to sub-ice-shelf currents. The second involved the indirect response of ice-shelf flow to the tidal signals observed in the ice streams that source the ice shelf. A finite-element model, based on viscous creep flow, was developed to test these hypotheses, but succeeded only in falsifying both hypotheses, i.e. showing that direct tidal effects produce too small a response, and indirect tidal effects produce a response that is not smooth in time. This nullification suggests that a combination of viscous and elastic deformation is required to explain the observations.
Incrementally Learning the Hierarchical Softmax Function for Neural Language Models

Neural network language models (NNLMs) have attracted a lot of attention recently. In this paper, we present a training method that can incrementally train the hierarchical softmax function for NNMLs. We split the cost function to model old and update corpora separately, and factorize the objective function for the hierarchical softmax. Then we provide a new stochastic gradient based method to update all the word vectors and parameters, by comparing the old tree generated based on the old corpus and the new tree generated based on the combined (old and update) corpus. Theoretical analysis shows that the mean square error of the parameter vectors can be bounded by a function of the number of changed words related to the parameter node. Experimental results show that incremental training can save a lot of time. The smaller the update corpus is, the faster the update training process is, where an up to 30 times speedup has been achieved. We also use both word similarity/relatedness tasks and dependency parsing task as our benchmarks to evaluate the correctness of the updated word vectors.
The Smart Energy Management of Multithreaded Java Applications on Multi-Core Processors

Multi-core processors are becoming widely deployed. However, more cores consume more power. A power saving technique for multi-core systems based on the observation of critical sections is proposed. Since only one thread works in a critical section, other threads on other cores that access the same resource would be busy waiting. The proposed power-saving technique leads to the energy savings (11 to 15 percent) and the lowest values of Energy Delay Product as compared with the other power-saving techniques.
D S ] 1 4 A pr 2 01 8 Partial resampling to approximate covering integer programs ∗

We consider column-sparse covering integer programs, a generalization of set cover, which have attracted a long line of research developing (randomized) approximation algorithms. We develop a new rounding scheme based on the Partial Resampling variant of the Lovász Local Lemma developed by Harris & Srinivasan (2013). This achieves an approximation ratio of 1 + ln(∆1+1) amin + O ( √
Comparing Effectiveness of Feature Detectors in Obstacles Detection from a Video

We have already proposed an obstacles detection method using a video taken by a vehicle-mounted monocular camera. In this method, correct obstacles detection depends on whether we can accurately detect and match feature points. In order to improve the accuracy of obstacles detection, in this paper, we make comparison among four most commonly used feature detectors; Harris, SIFT, SURF and FAST detectors. The experiments are done using our obstacles detection method. The experimental results are compared and discussed, and then we find the most suitable feature point detector for our obstacles detection method.
Pulmonary aspergillosis in immunocompetent patients without air-meniscus sign and underlying lung disease: CT findings and histopathologic features

Background Pulmonary aspergillosis in immunocompetent patients has been described as a saprophytic infection with pre-existing lung lesions showing an air-meniscus sign on chest radiograph or CT scans. There have been rare articles dealing with pulmonary aspergillosis in immunocompetent patients without pre-existing lung lesions. Purpose To evaluate the CT findings of pulmonary aspergillosis in immunocompetent patients without air-meniscus and underlying lung disease and to correlate the CT findings and pathologic features of pulmonary aspergillosis in these patients. Material and Methods A total of seven surgically proven pulmonary aspergillosis found in immunocompetent patients without an air-meniscus and underlying lung disease (M:F = 1:6; mean age 63.4 years) were included. On CT, the lesion shape, margin, type, location, diameter, presence of satellite nodules, presence of CT halo sign or hypodense sign, and interval growth were evaluated. Histopathologic features of each lesion were classified as one of the following; primary aspergilloma, chronic necrotizing pulmonary aspergillosis, or invasive pulmonary aspergillosis. Correlation between CT findings and pathological features was performed. Results All lesions presented as a nodule or mass unable to differentiate from malignancy. Most lesions had well-defined margins (n = 4), appeared as solid lesions (n = 7), and were located in the upper lobe (n = 5). Mean diameter of lesions was 2.3 cm. Satellite nodules (n = 2), CT halo sign (n = 1), and hypodense sign (n = 4) were found. Only one lesion increased in size during follow-up. Lesions were pathologically classified as primary aspergilloma (n = 3) and chronic necrotizing pulmonary aspergillosis (n = 4). The hypodense sign on CT was pathologically proved as dense fungal hyphae filled in bronchus and CT halo sign as parenchymal hemorrhage. Conclusion Pulmonary aspergillosis predominantly presented as a nodule or mass mimicking malignancy in the upper lobes on CT scan in elderly without underlying lung disease and immunosuppressive conditions except for age, and was histopathologically revealed to be either primary aspergilloma or chronic necrotizing pulmonary aspergillosis.
Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation

Tether proteins attach the endoplasmic reticulum (ER) to other cellular membranes, thereby creating contact sites that are proposed to form platforms for regulating lipid homeostasis and facilitating non-vesicular lipid exchange. Sterols are synthesized in the ER and transported by non-vesicular mechanisms to the plasma membrane (PM), where they represent almost half of all PM lipids and contribute critically to the barrier function of the PM. To determine whether contact sites are important for both sterol exchange between the ER and PM and intermembrane regulation of lipid metabolism, we generated Δ-super-tether (Δ-s-tether) yeast cells that lack six previously identified tethering proteins (yeast extended synatotagmin [E-Syt], vesicle-associated membrane protein [VAMP]-associated protein [VAP], and TMEM16-anoctamin homologues) as well as the presumptive tether Ice2. Despite the lack of ER-PM contacts in these cells, ER-PM sterol exchange is robust, indicating that the sterol transport machinery is either absent from or not uniquely located at contact sites. Unexpectedly, we found that the transport of exogenously supplied sterol to the ER occurs more slowly in Δ-s-tether cells than in wild-type (WT) cells. We pinpointed this defect to changes in sterol organization and transbilayer movement within the PM bilayer caused by phospholipid dysregulation, evinced by changes in the abundance and organization of PM lipids. Indeed, deletion of either OSH4, which encodes a sterol/phosphatidylinositol-4-phosphate (PI4P) exchange protein, or SAC1, which encodes a PI4P phosphatase, caused synthetic lethality in Δ-s-tether cells due to disruptions in redundant PI4P and phospholipid regulatory pathways. The growth defect of Δ-s-tether cells was rescued with an artificial "ER-PM staple," a tether assembled from unrelated non-yeast protein domains, indicating that endogenous tether proteins have nonspecific bridging functions. Finally, we discovered that sterols play a role in regulating ER-PM contact site formation. In sterol-depleted cells, levels of the yeast E-Syt tether Tcb3 were induced and ER-PM contact increased dramatically. These results support a model in which ER-PM contact sites provide a nexus for coordinating the complex interrelationship between sterols, sphingolipids, and phospholipids that maintain PM composition and integrity.
Cigarette Smoke and Asbestos Activate Poly-ADP-Ribose Polymerase in Alveolar Epithelial Cells

Abstract Background Cigarette smoke augments asbestos-induced bronchogenic carcinoma in a synergistic manner by mechanisms that are not established. One important mechanism may involve alveolar epithelial cell (AEC) injury resulting from oxidant-induced DNA damage that subsequently activates poly (ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair that can deplete cellular energy stores. We previously showed that whole aqueous cigarette smoke extracts (CSE) augment amosite asbestos-induced DNA damage and cytotoxicity to cultured AEC in part by generating iron-induced free radicals. We hypothesized that CSE increase asbestos-induced AEC injury by triggering PARP activation resulting from DNA damage caused by iron-induced free radicals. Methods Aqueous CSE were prepared fresh on the day of each experiment. PARP activity in WI-26 (a type I-like cell line) and A549 (a type II-like cell line) cells was assessed by the uptake of labeled NAD over 4 hours and confirmed on the basis of the reduction of PARP levels in the presence of a PARP inhibitor, 3-aminobenzamide (3-ABA). Cell survival was assessed by trypan blue dye exclusion. Results Hydrogen peroxide (H2O2; 1-250 μM), CSE (0.4-10 vol%), and amosite asbestos (5-250 μg/cm2) each caused PARP activation in WI-26 and A549 cells. The combination of asbestos (5 μg/cm2) and CSE (0.04-10%) induced WI-26 and A549 cell PARP activation without evidence of synergism. 3-ABA significantly attenuated WI-26 and A549 cell PARP activity and cell death after exposure to H2O2, CSE, and asbestos. Phytic acid, an iron chelator, catalase, and superoxide dismutase each decreased WI-26 cell PARP activation caused by asbestos and CSE. Conclusions CSE and asbestos induce PARP activation in cultured AEC in a nonsynergistic manner. These data provide further support that asbestos and cigarette smoke are genotoxic to relevant lung target cells and that iron-induced free radicals in part cause these effects.
Regional Approach for Iris Recognition

: Recent studies have explored a various set of techniques, methods and algorithms for iris recognition. Segmentation algorithms, normalization processes and well-deﬁned distances measures are employed as decision methods to compose the outline of all currently deployed systems, including commercial ones. So far, all systems make use of the entire iris pattern of any individual, assuming that a ﬁxed threshold applied on the distance can partially avoid problems like noise of information and acquisition errors. In this paper a new approach is presented that uses only selected sectors of the iris and a simple analysis strategy, for veriﬁcation purposed. Therefore, it differs from all previous approaches that process the entire iris pattern. In addition, three Bayes-based similarity measures have been considered for iris image matching: the Whitened Cosine (WC), the PRM Whitened Cosine Transform (PWC) and the Whitin-class Whitened Cosine Transform (WWC). The experimental results, carried out using the CASIA database, are encouraging and demonstrate that the proposed approach supports several directions for further research.
ACM Transactions on Human-Robot Interaction

Welcome to the inaugural issue of the ACM Transactions on Human-Robot Interaction! It is an exciting time to be part of the HRI community. Across its publication venues, Human-Robot Interaction is producing a burgeoning and compelling body of intellectual activity. ACM THRI is truly honored to participate in these developments as the first robotics journal offered by ACM Publications. As Editors-in-Chief, Chad and I are privileged to work with an esteemed and thoughtful editorial board in our consideration of research comprising the leading thought in HRI. Our editorial board has been thrilled to see inspiring research flowing through the journal, across the Behavioral/Social, Computational, Design, and Mechanical sections, and remain excited for the new work to come. In complement to ACM THRI, this March witnessed the gathering of the largest-ever group of almost 650 Human-Robot Interaction scholars in Chicago for the annual ACM/IEEE Human-Robot Interaction Conference. As the community of HRI researchers grows, we must ever more carefully consider how to keep up the rigorous nature of HRI research, while working to include a greater diversity of perspectives into the conversation. Being the premier journal in the field of HumanRobot Interaction, ACM THRI considers broad representation of high quality work as central to its mission. We are therefore committed to enabling the inclusion and dissemination of HRI research across disciplinary and geographical audiences, and to broadening the field’s scientific and societal impact. To highlight our aims for HRI and ACM THRI, this inaugural issue has focused on the topic of “New Frontiers for Human-Robot Interaction” with a combination of opinion editorials and top-quality research articles. Among these research articles, Bowen and Alterovitz present new insights into motion planning for dynamic human environments through the estimation of cost functions learned from demonstration. Carrillo et al. describe the innovative process of designing a social robotic rehabilitation aid for children with cerebral palsy, performed in the context of clinical deployment and with sustained engagement of diverse stakeholders. Lee and Riek’s critical look at assistive robots being developed for older adults suggests we need to go beyond the deficit
A Selected Summary of AI for Computational Sustainability

This paper and summary talk broadly survey computational sustainability research. Rather than a detailed treatment of the research projects in the area, which is beyond the scope of the paper and talk, the paper includes a meta-survey, pointing to edited collections and overviews in the literature for the interested reader. Computational sustainability research has been broadly characterized by AI methods employed, sustainability areas addressed, and contributions made to (typically, human) decision-making. The paper addresses these characterizations as well, which will facilitate a deeper synthesis later, to include the potential for developing sophisticated and holistic AI decision-making and advisory agents.