Miracle-dz/UniFAR-FTUs huggingface dataset:
Elevated D-dimer increases the risk of dialysis after surgery in patients with Stanford A aortic dissection through the impact of the coagulation system.

Background To investigate whether Elevated D-dimer increases the risk of dialysis after surgery in patients with Stanford A aortic dissection. Methods A total of 120 patients with type A aortic dissection who underwent surgery at our institution from August 2014 to December 2015 were enrolled in the study. Acute type A aortic dissection was treated with Sun's operation. Blood samples were collected before anesthesia induction, 4 hours after surgery, and 24 hours after surgery. Patients were divided into two groups according to their D-dimer levels. Group A had D-dimer concentrations below 3,000 µg/L; Group B had D-dimer concentrations above 3,000 µg/L. Results Group A (n=99; 82.5% of total patients) had D-dimer levels below 3,000 µg/L. Eighteen patients in Group A (18.18%) died within 30 days after surgery. Group B (n=21; 18.5% of total patients) had D-dimer levels above 3,000 µg/L. Seven patients in Group B (28%) died within 30 days after surgery. A significantly higher percentage of patients in Group B had acute renal failure and the application of continuous renal replacement therapy (P=0.02). There were significant differences between the groups in intraoperative blood loss (P=0.001) and hemostatic drugs administered, such as intraoperative prothrombin complex (P=0.015). The D-dimer (P<0.001), FIB (P=0.008) and FDP (P<0.001) in the B group were significantly higher than those in the A group, but there was no significant difference between the 4 hours after the operation and the 24 hours after the operation. Thromboelastogram (TEG) examination showed that preoperative R in group B was shorter than the A group, 4 hours after operation was still lower in group B than in group A. Through ROC analysis, D-dimer is a prognostic indicator for postoperative renal failure. When cut-off =1,039.00, sensitivity =91.7%, specificity =54.2%. When D-dimer is below 1,039 µg/L, the risk of dialysis after surgery in patients with Stanford A aortic dissection is low. Prognostic value of D-dimer was evaluated using ROC analysis and the results showed that the area under curve (AUC) of D-dimer as prognostic indicator for postoperative renal failure was 0.741 (95% CI, 0.642-0.840; P value<0.001). Stepwise binary logistic regression analysis revealed that total suspended red, wakefulness delayed, D-dimer were independent predictors of dialysis risk after surgery in patients with Stanford A aortic dissection among all the other factors. Conclusions D-dimer above 3,000 µg/L increases the risk of dialysis after surgery in patients with Stanford A aortic dissection through the impact of the coagulation system. When D-dimer is below 1,039 µg/L, the risk of dialysis after surgery in patients with Stanford A aortic dissection is low.
Des jeux et des musées de sciences et techniques

RESUME : A travers trois exemples de jeux serieux, cet article montre que les jeux peuvent etre des bons mediateurs scientifiques dans les musees. Il decrit cependant quelques precautions a prendre pour que le but soit atteint. Il conclut enfin qu'un jeu serieux apporte bien plus qu'une mediation scientifique. ABSTRACT: Through 3 exemples of serious games, this article shows that games are strong cultural mediator if carefully designed. It prooves also that they could be much more than scientific mediator.
Self-Determination Calibration for Cochlear Implant Rehabilitation

Cochlear implantation is a well-established therapeutic approach for deaf or hearing-impaired patients. After the medical intervention, which aims to restore hearing, subjects undergo rehabilitation procedures in order to cure instructional disadvantages, problematic schooling circumstances, or deficits in their sociability. Essential physical, mental, social, and cognitive skills are taken into perspective, as the prerequisite of a notable aptitude determines the suitability of a subject to get professional and communal roles. Quality of life, as an indicator, provides the metrics that demonstrate the level of adoption with established norms.
D5.3.2 Revision and Extension of the NeOn Development Process and Ontology Life Cycle

This deliverable presents the revision and extension of the ontology network development process, the ontology network life cycle models and the ontology network life cycle included in deliverable D5.3. 1. The main contributions included in this document are (1) the improved version of the NeOn Glossary, (2) the updated of the collection of ontology network life cycle models, (3) the enhancement of the guidelines for scheduling ontology network projects and (4) the proposal of a NeOn plug-in, called gOntt, for helping people to schedule ontology projects.
Low Back Pain in Young and Middle-Aged People

The low back pain in the young and middle-aged people is character- ized by "so-called low back pain," or nonspecific low back pain in which the cause is difficult to identify, that is more common compared with other age groups. Behind the high incidence of nonspecific low back pain of young and middle-aged people lies the fact that these people must maintain a high degree of activity of daily life at the time when the aging-related changes in the lumbar spine and tissues sur- rounding the lumbar spine start to occur, thus creating a gap between social needs and physical capabilities. Nonspecific low back pain must often be diagnosed based on exclusion, and it is important in particular to differentiate serious diseases such as spinal tumor and infectious spine diseases. Symptomatic therapies and instructions on daily life are performed mainly as the treatment methods, thereby it is important to eliminate patients' anxiety by explaining that the condition is not a disease of malignant nature and that no concern is needed in this regard. In the case of acute pain, it is also important in the treatment to prevent the condition from becoming chronic. The onset of nonspecific low back pain involves various factors, and socio-psychological factors may also be involved as an important cause, besides structural and physiological abnormalities in the lumbar region. In responding to the complaint of low pack pain, tackling this disease by grasping the whole picture of each patient's life from the standpoint of a living function-related disease, instead of merely providing anti-inflammatory analgesics, is considered to lead to early social rehabilitation.
Analysis and optimizations for modern processors' branch target buffer and cache memory

Microprocessor architecture has changed significantly since Intel Corporation developed the first commercial computer chip in the 1970s. The modern processors are much smaller and more powerful than their predecessors. Yet, in the mobile computing era the market demands for smaller, faster, cooler, and more power-efficient CPUs that could provide greater performance-per-watt results. In this dissertation, we address some of the shortcomings in conventional microprocessor designs and discuss possible means of alleviating them. First, we investigate the energy dissipation in Branch Target Buffer (BTB), a commonly present component in branch prediction unit. Our primary contribution is a speculative allocation technique to improve BTB energy consumption. In this technique, a new on-chip structure predicts the BTB activity and dynamically eliminates unnecessary accesses. Next, we formulate a quantitative metric to analyze the trade-off between processor energy efficiency and cache energy consumption. We investigate the upper bound energy and latency budget available for alternative data and instruction cache enhancements. This dissertation concludes with a novel approach to increase processors’ performance by reducing data cache miss rate. We employ a speculative technique to bridge the performance gap between the common Least Recently Used (LRU) replacement algorithm and the optimal replacement policy. We evaluate the non-optimal decisions made by the LRU algorithm and provide a taxonomy of mistakes, which will aid to identify and avoid similar decisions in future incidents.
Seasonal and clock angle control of the location of flux transfer event signatures at the magnetopause

[1] Most models of flux transfer event (FTE) formation produce pairs of structures which in general move away from the subsolar region and give rise to signatures which can be observed in both the Northern and Southern Hemispheres. The multiple reconnection line (X line) model is unusual as a reconnection-based model that is capable of producing a single flux rope if only two X lines are present. Raeder (2006) reported the results of an MHD simulation where he studied the effect of the Earth’s dipole tilt on reconnection at the dayside magnetopause for a southward IMF orientation; in his simulations, flux ropes were formed by the sequential formation of X lines, and when the dipole tilt was set to a value representative of solstice the flux ropes moved preferentially toward the winter hemisphere. Some observational evidence has previously been presented for a bias toward FTE signatures being observed in the winter hemisphere; in this paper, we present further observational evidence for this phenomenon, using an independently derived data set. Once the seasonal bias is taken into account, we find that the IMF clock angle controls the location of FTE signatures. We also find that the effective dipole tilt (combining the geomagnetic dipole tilt with the IMF tilt angle) provides no clear control of the location of FTE signatures.
REVIEW ON EARLY DETECTION OF MELANOMA IN SITU

Skin cancer is the fifth most common type in the united state. It has become a major health issue in the world over the past 40 years and its incidence has increased in recent years. Early detection is an efficient way to diagnose and manage skin cancer. Detection at the melanoma in situ (MIS) stage provides the highest cure rate for melanoma. The ultimate aim of this paper is to provide an overview of statistics and the result of the most important implementation that exist in the literature, while it compare the performance of different classification on pigmented skin lesion (PSL) and also focusing on several segmentations and feature extraction methods. Index Term:- skin cancer, melanoma, melanoma in situ (MIS), pigmented skin lesion (PSL) , segmentation, feature extraction, classification.
Rozvíjení gramotnosti ve výuce na 1. stupni ZŠ

Studijni texty přinaseji budoucim ucitelům na 1. stupni zakladni skoly sirsi nahled na problematiku gramotnosti. Objasňuji význam dovednosti cteni a psani v životě žaka (clověka) a obsahuji vybrane metody a formy rozvijeni pocatecni ctenařske gramotnosti. Prvni cast objasňuje filozofii soucasneho přistupu k budovani zakladů gramotnosti. Ve druhe casti jsou postupně komentovany jednotlive složky funkcni gramotnosti, ktera je na zakladnich skolach pravidelně posuzovana v mezinarodnich srovnavacich testech. Konecně třeti cast obsahuje nacrt některých cinnosti a metod, kterými můžeme gramotnostni dovednosti rozvijet teměř ve vsech předmětech skolniho kurikula.
THE RETICULAR FORMATION REVISITED

The reticular formation (RF) is one of the most fruitful conceptions of recent years in the field of the physiology and pathology of the central nervous system. Yet many aspects of the anatomy and physiology of the R F are still shrouded in the haze of uncertainty and doubt, owing partly to technical difficulties and partly to the difficulty of correlating the findings obtained in histological and in physiological investigations. Thus the term “RF’ has come to mean different things to the anatomist, the histologist and the physiologist. For the anatomist, the formafio reticuluris, or white and grey reticular formation, is a morphological unit consisting of nervous tissue filling the interspaces among the large ascending and descending fibre tracts and sensory and motor nuclei of the brain-stem. For the histologist, the R F is not a morphological unit but an aggregate of different units or nuclei, giving origin to nerve fibres with \different destinations, lengths and numbers of collateral branches. Recently the number of nuclei in the R F of the cat and man have been mapped out: their number runs into several scores, but to only a few of them is it possible to attribute a definite function. For the physiologist, the R F has been for a long time a notable region containing vital centres, such as the respiratory, cardiac, vasomotor and vomiting centres, Recent investigations suggest that, in addition to these centres, the RF contains nuclei which control the action of the spinal anterior horn cells and of the cerebral cortex. Three main physiological systems may be distinguished in the RF:
The Outlier Knowledge of Products Based On Grey Privacy Information

Product attributes are closely related to consumers' willingness to buy on e-commerce. Some products are considered that few people would buy them online, but in fact they have large sales volume, such as underwear products. This study analyzed from the perspective of the product grey private information of why consumers buy and who is buying these products, what kind of relationship between the purchasing comments and product attributes of these products. Firstly, we select the companies with certain influence to the exploratory research to study the company's comments, and do the data mining of the top 10 products of the best sales and the last 10 products of the poor sales. Secondly, we analyzed the product attributes of the 14 enterprises again by the iterative method and compared with the first exploration result. Thirdly, we studied on the value of common knowledge and outlier knowledge for these products. The study found that common knowledge has the sensitive interval for the price of grey private products, the product price, the discount of the product and the sales volume of the product have significant relationship. The discovery of outlier knowledge is open and the comfort is very different. There is a significant positive correlation between the time of marketing and the sales volume: simple, natural, health products and sales are related; the extreme situations are not universal, but have good room for growth.
TRENDS OF HEMATOLOGICAL AND BIOCHEMICAL VALUES IN THE BLOOD OF YOUNG RACE HORSES DURING STANDARDIZED FIELD EXERCISE TESTS

The aim of this study was to compare the changes in hematological and biochemical parameters in race horses subjected to standardized field exercise tests. The tests were performed two times: in May, at the beginning of the racing season and then four months later. Ten horses were studied in May (5 Thoroughbreds and 5 Purebred Arabian horses). Eight horses were studied in September (4 Thoroughbreds and 4 Arabian horses). For each horse, venous blood samples were collected at rest, after warm-up, just after the end of each gallop, and 30 minutes after the end of the exercise. The concentration of blood lactic acid (LA) hemoglobin (Hb), plasma glucose (Glc), triacylglycerols (TG), glycerol, uric acid (UA), total protein, total thiobarbituric acid-reactive substances (TBARS), the activity of lactate dehydrogenase (LDH), kreatine kinase (CK) and aspartate aminotransferase (AST) and the total antioxidant status (TAS) were determined. The standardized field exercise test performed in September, in comparison to the first test, evoked the lowest increase in blood LA and plasma Glc and TG levels determined during exercise. The rapid return of elevated levels of LA, Hb and UA to their initial values was also observed in September, as compared to data obtained in May.
Efficient adaptive thresholding with image masks

Adaptive thresholding is a useful technique for document analysis. In medical image processing, it is also helpful for segmenting structures, such as diaphragms or blood vessels. This technique sets a threshold using local information around a pixel, then binarizes the pixel according to the value. Although this technique is robust to changes in illumination, it takes a significant amount of time to compute thresholds because it requires adding all of the neighboring pixels. Integral images can alleviate this overhead; however, medical images, such as ultrasound, often come with image masks, and ordinary algorithms often cause artifacts. The main problem is that the shape of the summing area is not rectangular near the boundaries of the image mask. For example, the threshold at the boundary of the mask is incorrect because pixels on the mask image are also counted. Our key idea to cope with this problem is computing the integral image for the image mask to count the valid number of pixels. Our method is implemented on a GPU using CUDA, and experimental results show that our algorithm is 164 times faster than a naïve CPU algorithm for averaging.
Highly optimized transitions to turbulence

We study the Navier-Stokes equations in three dimensional plane Couette flow geometry subject to stream-wise constant initial conditions and perturbations. The resulting two dimensional/three component (2D/3C) model has no bifurcations and is globally (non-linearly) stable for all Reynolds numbers R, yet has a total transient energy amplification that scales like R/sup 3/. These transients also have the particular dynamic flow structures known to play a central role in wall bounded shear flow transition and turbulence. This suggests a highly optimized tolerance (HOT) model of shear flow turbulence, where streamlining eliminates generic bifurcation cascade transitions that occur in bluff body flows, resulting in a flow which is stable to arbitrary changes in Reynolds number but highly fragile in amplifying arbitrarily small perturbations. This result indicates that transition and turbulence in special streamlined geometries is not a problem of linear or nonlinear instability, but rather a problem of robustness.
Natural language processing of visual language for image storage and retrieval

A natural language processing system is constructed that can interpret text based descriptions of physical objects and create three-dimensional graphic models of the objects. The system design is based on the integration of current theories of human linguistic and visual processing. The system embodies principles for the representation and processing of objects and interpart relationships that permit communication between verbal and vision subsystems. The principles are primary dimensionality, partwise decomposition, and part relationship schematization. The meanings of some shape words such as "width" or "oval" are sensitive to the primary dimensionality of subject. Partwise decomposition simplifies communication by defining differences between complex objects as simple differences in their parts. The meanings of the relations between parts of an object are idealized into a simpler part relationship schematization with few attribute slots. Domain knowledge and domain independent knowledge of physical part interactions are used to control semantic interpretation and build internal models of the meaning of the text. The domain independent knowledge includes mechanisms for processing selected shape and spatial descriptions. Semantic interpretation of language involves the selection of prototypical shapes from a three-dimensional domain model. Additional linguistic constructs specify modifications to the shape of the prototypes. In a controlled experiment, the system processed descriptions of leaves and acorns from a field guide. Subjects were able to match original text to computer generated images as well as they could match the text to the artist generated images of the objects from the same field guide. This finding is evidence for the descriptive adequacy and computational tractability of this approach to the integration of language and visual processing.
Politicization in the EU: between national politics and EU political dynamics

ABSTRACT The EU has become increasingly politicized not only at the bottom, due to polarized debates, divided electorates, declining mainstream parties, and rising Euroskeptic populism; or from the bottom up, as national politics permeates member-state leaders’ positions in the Council. It has also emerged purely at the top, in the increasingly politically charged dynamics of interaction within and among EU actors. Such politicization involves struggles for power and influence that are ideational as much as institutional and coercive. Current theorists of EU integration, because of their tendency to focus on only one or another EU actor have overlooked the EU’s politicized dynamics, even though their accounts, taken together, provide ample evidence of it. The article shows that the EU has gone from what was once metaphorically described with the catchphrase of ‘politics without policy’ at the national level to ‘politics against policy’ in more contentious areas, whereas at the EU level it has moved from ‘policy without politics’ to ‘politics with policy’. The paper illustrates with the cases of the Council and the Commission in the Eurozone crisis.
Access to Online Resources: A Case Study

The implementation and use of a Blackboard virtual learning environment (VLE) is described. The VLE was accessible by all Part 1 psychology students at the University of Reading. Data show that students readily made use of the VLE although there were age and gender differences in accessing the VLE that interacted with other variables. Importantly, although there were some minor differences between patterns of access by students with home access to the internet and students without such access, there were no differences in overall access rates. Data also show that this cohort of students performed significantly better than the previous cohort on Part 1 exams but there was no correlation between access to the VLE and Part 1 exam results.
The Illicit Distribution of Precursor Chemicals in China: A Qualitative and Quantitative Analysis

China has been marked as a source country from which large volumes of precursor chemicals are shipped to foreign drug markets for synthetic drug production. However, the basic patterns of illicit distribution remain unclear. Data from closed criminal cases were extracted from legal files to develop an objective understanding of illicit distribution patterns in China. The sample consisted of 534 illicit supply cases involving 1481 individuals, three groups of precursor chemicals and 102 chemical manufacturing companies. The offenders could be categorised as lower-class offenders, occupational offenders and corporate offenders based on their profiles and criminal behaviours. Significant differences between the three groups of offenders and their specific patterns of chemical supply suggest a diverse, dynamic and complex nationwide supply network. To better understand this phenomenon in China’s rapidly transitioning society, we provide a description of cultural, legal and political backgrounds, which may provide some explanations at the macro level.
MVC-RA: múltiplas visões coordenadas em ambientesde realidade aumentada

Versa sobre a aplicacao das caracteristicas de um ambiente de realidade aumentada, tais como: interacao facil e intuitiva, e grande espaco para visualizacao de dados, na implementacao, interacao e visualizacao de multiplas visoes de dados coordenadas. As multiplas visoes de dados permitem que o usuario realize uma melhor analise dos dados sobre diferentes aspectos, e a coordenacao entre as multiplas visoes tem o objetivo de diminuir a sobrecarga oogniriva conferida ao usuario. O ambiente aumentado foi concebido atraves do ARToolKit, a interacao se da atraves de uma interface baseada em cartoes marcadores. A tecnica implementada foi Dispersao de Dados 3D, acompanhada de uma diversidade de filtros e configuracoes para as visoes de dados. Por fim, sao apresentados alguns ensaios de usabilidade preliminares do prototipo desenvolvido.