Miracle-dz/UniFAR-FTUs huggingface dataset:
Xyce Parallel Electronic Simulator Users' Guide Version 6.12.

This manual describes the use of the Xyce Parallel Electronic Simulator. Xyce has been designed as a SPICE-compatible, high-performance analog circuit simulator, and has been written to support the simulation needs of the Sandia National Laboratories electrical designers. This development has focused on improving capability over the current state-of-the-art in the following areas: • Capability to solve extremely large circuit problems by supporting large-scale parallel computing platforms (up to thousands of processors). This includes support for most popular parallel and serial computers. • A differential-algebraic-equation (DAE) formulation, which better isolates the device model package from solver algorithms. This allows one to develop new types of analysis without requiring the implementation of analysis-specific device models. • Device models that are specifically tailored to meet Sandia’s needs, including some radiation-aware devices (for Sandia users only). • Object-oriented code design and implementation using modern coding practices. Xyce is a parallel code in the most general sense of the phrase — a message passing parallel implementation — which allows it to run efficiently a wide range of computing platforms. These include serial, shared-memory and distributed-memory parallel platforms. Attention has been paid to the specific nature of circuit-simulation problems to ensure that optimal parallel efficiency is achieved as the number of processors grows.
Fast hyperbolic mapping based on the hierarchical community structure in complex networks

The hyperbolic geometry of complex networks has recently emerged as a promising framework for the analysis of real and synthetic networks; one significant challenge of the hyperbolic geometry framework is the necessity to map large real networks to latent geometric spaces. Addressing this problem, we present a novel fast hyperbolic mapping algorithm called hyperbolic mapping based on the hierarchical community structure (HMCS), which is based on the network evolution model, the community-sector model in hyperbolic space and the hierarchical community structure (HCS) of complex networks. We present an index called community closeness (CC) to measure the adjacency relationship between the communities. Then we propose a ranking algorithm for first-level and second-level communities based on CC to determine the order of communities on the hyperbolic disc and map the network into hyperbolic space based on the order and the angular range of the corresponding sector of the second-level communities. We find that HMCS greatly reduces the mapping time complexity and achieves linearity () in sparse networks under the premise of ensuring better mapping accuracy compared with existing hyperbolic mapping algorithms. Experiments show that the HMCS algorithm occupies a unique attractive position in the space of tradeoffs between mapping accuracy and computational complexity.
2D Percolation Design with Conductive Microparticles for Low‐Strain Detection in a Stretchable Sensor

Although a variety of stretchable strain sensors based on electrical percolation have been reported, stretchable sensors detecting low strains have been rarely demonstrated. This is because large stretchability of a strain sensor conflicts with high strain resolution at low strains. Here, the electrical percolation into 2D is confined and a strain sensor that is highly sensitive at low strains and simultaneously highly stretchable is presented. The 2D confinement of the electrical percolation is accomplished by a close‐packed monolayer assembly of conductive microparticles (MPs) on an elastomer substrate. The current profiles of the MP monolayer at low strains are in situ visualized using conductive atomic force microscopy. When the lattice of the MP monolayer is aligned vertically to the strain direction, the resistance is highly sensitive to low‐strain deformations (ε = 0 – 0.05), but the sensor has reasonable stretchability (ε = 0.3). The simultaneous achievement of the high sensitivity at low strains and the reasonable stretchability is explained by the relationship between the strain‐dependent current profile and the relative position changes of the MPs. A high‐precision pulse sensor clearly showing the representative peaks is demonstrated.
Pulmonary embolectomy – where in the aspect of the new European Society of Cardiology guidelines for diagnosis and management of acute pulmonary embolism of 2009 is a place for cardiac surgery? Case report

Przedstawiono opis przypadku 53-letniej pacjentki, która w wyniku ciężkiego urazu komunikacyjnego doznała licznych obrażeń w zakresie miednicy i klatki piersiowej. Stwierdzono u niej złamanie obu kości udowych, kości łonowej i krzyżowej z przemieszczeniem odłamów kostnych, złamanie obojczyka i żeber II–IV. Stwierdzono także odmę opłucnową, którą zaopatrzono drenażem ssącym. W 3. dobie po urazie pojawiła się narastająca niewydolność oddechowa, a w dodatkowym badaniu tomografii komputerowej (TK) z kontrastem rozpoznano zatorowość tętnic płucnych. Wobec przeciwwskazań do leczenia trombolitycznego po konsultacji podjęto decyzję o przewiezieniu pacjentki do kliniki kardiochirurgii, gdzie niezwłocznie operacyjnie usunięto masywny materiał zatorowy. Szybka decyzja o zmianie profilu leczenia z terapii pacjenta urazowo-ortopedycznego do leczenia pacjenta kardiologiczno-kardiochirurgicznego pozwoliła na opanowanie ciężkiego stanu nagłego pacjentki, który w 7–11% kończy się zgonem. Słowa kluczowe: kardiochirurgia, embolektomia płucna, operacja ratująca życie. Abstract
The Development of Problem-Based Learning Material for Integrated Science Subject in Primary Teacher Education Program

This research and development aim to develop a learning material for the learning improvement quality of Primary Teacher Education (PGSD) students in Integrated Science subject. The research method used is Borg and Gall model. The research stages are: (a) curriculum analysis, the students’ and teachers’ need analysis, (b) the learning material development stage which is analyzed by experts’ judgment, and (c) the pilot stage. The research instruments are observation sheets, interview guides, validation sheets, teachers and students’ response questionnaires, tests, performance assessment sheets, and attitude questionnaires. The results show that the learning material is valid, practical and effective to improve Integrated Science subject learning quality.
Software digital sociology

With the continuous development of the internet, software development (especially global open-source development) is facing critical challenges, such as individual differences in developers distributed worldwide, the increasing difficulty of group collaboration, and the complex ecosystems formed by extensive social participation. These problems exhibit strong sociological characteristics in regard to the activity of software development. This study proposes the concept of software digital sociology that involves mining abundant software-activity data to investigate individual learning, group collaboration, and sustainable ecosystems. We discuss the primary investigation of the critical issues associated with the open-source supply chain and suggest that software digital sociology can inspire software-development researchers to understand the key challenges posed by extensive (computer-mediated) social participation to promote exploration of solutions using a different paradigm.
Review of Optimization Methods in Medical Imaging

Digital medical images play a major role in clincal detection of the patient and determine the appropriate treatment for the condition. Because of the exposure of medical digital images to several factors that affect their clarity, accuracy, noise or quality, there was a need for techniques to improve medical images and maintain the information in them, as this information is very important and related to the patient's health and diagnosis of his condition. There are many techniques to optimize the medical images that will be mentioned in this research, explain them, and discuss the challenges and difficulties of optimizing digital images in the medical domain.
CARDIOTOXICITY AND USE OF HERBAL DRUGS- A REVIEW

Cardiotoxicity is the occurrence of heart electrophysiology dysfunction and/or muscle damage. Acute myocardial infarction (MI), the most important consequence of cardiotoxicity, is the necrosis of a region of myocardium caused by an interruption in the supply of blood to the heart usually as a result of occlusion of a coronary artery. Evidence suggests that oxidative stress resulting from increased production of reactive oxygen species (ROS) may play a important role in the pathogenesis of myocardial infarction. There is evidence that antioxidants can protect against free radical defense, which is responsible for reperfusion-induced damage and thereby inhibit myocardial damage and arrhythmias during acute myocardial infarction. Various studies showed that the natural antioxidants have very less toxicity and proved to be safer and effective and they scavenge the free radicals and avoid excess ROS formation in the body thereby helping in mitigating cardiac diseases and several other disorders. Many herbal medicines have been reported to contain large amount of antioxidants. Many herbal drugs have observable beneficial actions on the heart serving as cardiotonics. Where in, digoxin (Lanoxinin) is even clinically prescribed for the treatment of congestive cardiac failure. Though herbal drug industry is growing at an astounding rate all over the world, their efficacy and safety is always questioned. There are only "evidence-based" medicine and "as-yet unproven" medicine, regardless of origin, conventionality or approach. Some of the herbal drugs which are good antioxidants, besides their use for cardiac insufficiency and other cardiac disorders are in turn responsible for causing potential cardiotoxic adverse effects. Thus, herbal products not regulated as medicines cannot be seen as alternative therapies unless they are shown to be equally effective as accepted agents.
Scrambling the skin: Simulated Skin Re-Arrangement Using Apparent Motion

An age-old hypothesis proposes that object motion across the receptor surface organizes sensory maps (Lotze, 19th century). Skin patches learn their relative positions from the order in which they are stimulated during motion events. We test this idea by reversing the local motion within a 6-point apparent motion sequence along the forearm. In the ‘Scrambled’ sequence, two middle locations were touched in reversed order (1-2-4-3-5-6, followed by 6-5-3-4-2-1, in a continuous loop). This created a local acceleration, a double U-turn, within an otherwise constant-velocity motion, as if the physical location of skin patches 3 and 4 was surgically swapped. The control condition, ‘Orderly’, proceeded at constant velocity at inter-stimulus onset interval (ISOI) of 120 ms. In the test, our twenty participants reported motion direction between the two middle tactors, presented on their own at 75, 120 or 190-ms ISOI. Results show degraded motion discrimination following exposure to Scrambled pattern: for the 120-ms test stimulus, it was 0.31 d’ weaker than following Orderly conditioning (p = .007). This is the aftereffect we expected; its maximal expression would be a complete reversal in perceived motion direction between locations 3 and 4 for either motion direction. We propose that the somatosensory system was beginning to ‘correct’ reversed local motion to uncurl and remove the U-turns that always occurred on the same part of the receptor surface. Such de-correlation between accelerations and their location on the sensory surface is one possible mechanism for organization of sensory maps.
Haemodynamic parameters in hypertensive patients following acute stroke and early outcome

Background Stroke remains the third commonest cause of death in adults and second cause of death amongst over 60 years of age. It is the commonest cause of severe disability. Stroke outcome remains poor in the United Kingdom compared to Western Europe. Currently, manipulating modifiable risk factors, namely hypertension, diabetes mellitus etc, remains the focus of interest in acute stroke research. With the better understanding of haemodynamic parameters it is known that cardiac baroreceptor sensitivity (BRS) plays an important part in the short-term blood pressure control. It is recognised that impaired cardiac BRS, measured 72-hours post-ictus, predicts poor death/dependency in long-term. There is a suggestion that increased arterial stiffness affecting baroreceptors in aortic arch and carotid artery may account for impaired cardiac BRS in acute stroke. However, the role of cardiac BRS and arterial stiffness in predicting early (2-week) death/dependency following acute stroke in subjects on pre­ existing antihypertensive therapy is not known. Hypothesis Central, rather than peripheral, arterial compliance is a better predictor of cardiac BRS. There is relationship between baseline cardiac BRS and central arterial stiffness and both are independent predictors of early (2-week) outcome following acute stroke. Methods This thesis evaluates their predictive role for early outcome in a subgroup of an ongoing trial, the Continue Or Stop post-Stroke Antihypertensive Collaborative Study (COSSACS). Findings Cardiac BRS and arterial stiffness are negatively correlated, though this relationship is not significant when adjusted for common confounders. Lower beat-to-beat mean arterial pressure (MAP) and central systolic blood pressure (SBP) in acute phase of stroke (<48 hours), but not cardiac BRS or arterial stiffness predict early outcome. Conclusions These findings have important implications for the management of acute stroke hypertension, including the continuation or discontinuation of pre-existing antihypertensive therapy, given the presence of cerebrovascular dysautoregulation following acute stroke. Randomised, controlled, intervention studies are ongoing to inform the management of this common problem.
Utilisation de matériaux naturels modèles pour la formulation de mortier contenant des sables et des fines de granulats recyclés

Les granulats de beton recycle (GBR) ne sont pas suffisamment utilises dans le secteur de la construction, principalement en raison de leur grande capacite d’absorption d’eau. Ces materiaux sont en effet composes de granulats naturels concasses et de pâte de ciment durcie adherente qui possede une forte porosite. La premiere partie de ce travail de recherche s’interesse a la valorisation des GBR de dimensions inferieures a 4 mm (sables recycles) dans une formulation de mortier. Les comportements a l’etat frais et durci de mortiers fabriques soit avec un sable recycle soit avec un sable naturel modele sont compares. Le sable naturel modele est concu dans le but d’obtenir des caracteristiques physiques proches de celles du sable recycle. Cette demarche permet de mettre en evidence l’influence de la substitution d’un sable naturel par un sable recycle de caracteristiques voisines. La seconde partie de ce travail consiste a trouver une piste de valorisation pour les particules de GBR inferieures a 125 µm. L’objectif est ici d’utiliser la poudre issue du broyage de GBR comme addition minerale. Un travail de caracterisation de la poudre recyclee permet de mettre en evidence que la fine recyclee reste poreuse apres broyage. Un modele theorique et une methodologie experimentale permettant d’estimer cette porosite sont developpes. Enfin, des mortiers fabriques avec un filler calcaire et une fine recyclee sont compares, les resultats montrent que la fine recyclee peut etre utilisee comme addition minerale.
Influence of escaping of Na & K on physical properties in lead-free Na0.92K0.08NbO3 ceramic

Abstract Lead-free Nax K1–xNbO3 (NKN) ceramic with x = 0.08 was prepared by a conventional solid-state reaction method to investigate the influence of the Escaping of Na & K on their physical properties. It has been found that the NKN ceramics with x = 0.08 exhibit pure perovskite (ABO3) structure. The pure phase NKN was achieved for all sintering temperatures of 1100 °C, 1150 °C, 1200 °C and 1250 °C. Change in microstructure, indicates that the grain size increases with the increasing sintering temperatures. The dielectric constant was dependent of the Escaping of Na & K. From the analyses, we suggest that the high dielectric constant for the NKN ceramics near sintering temperature 1150 °C are closely related to their low escaping of Na & K and microstructures of uniformly distributed large grains rather than the widely believed morphotropic phase boundary effect of lattice parameter discontinuity.
Effect of Endurance Training with Royal Jelly on CRP Gene Expression in Muscle Tissue of Rats with Alzheimer ’s Disease

Background: StudieshaveshownthatAlzheimer’sdisease(AD)causesneuromusculardysfunctionbydamagingdiﬀerentpartsof the central nervous system and inﬂammation that can increase C-reactive protein (CRP) levels. Nevertheless, the beneﬁcial eﬀects of endurance training (ET) and royal jelly (RJ) on inﬂammation and reduction of CRP are not fully elucidated. Objectives: The aim of this research was to investigate the eﬀect of ET with RJ on gene expression of CRP in muscle tissues of rats with AD. Methods: In this experimental study, 24 rats with AD (8 mg/kg trimethyltin injection) were randomly divided into four groups of 1-ET,2-ET+[RJ(100mg/kg)],3-RJand4-control. Also,sixhealthyratswereplacedinthehealthycontrolgrouptoinvestigatetheeﬀects of AD induction on CRP gene expression. Endurance training groups performed endurance training with a speed of 15 - 20 m/min, 5 sessions per week for eight weeks. Results: Our ﬁndings showed ET and RJ signiﬁcantly decreased CRP gene expression in muscle tissues of rats with AD (P = 0.001) as well as the interaction of ET and RJ was signiﬁcant in reducing CRP gene expression in muscle tissues of rats with AD (P = 0.001). Conclusions: It appears that ET and RJ have interactive eﬀects on the reduction of CRP in muscle tissues of rats with AD.
Desafios no tratamento de linfoma difuso de células B em pacientes jovens

O linfoma difuso de grandes células B (LDGCB) é a doença maligna linfoide mais comum, e apresentou um aumento significativo da sua incidência nos últimos 20 anos. Os linfomas não Hodgkin (LNH) representam um grupo heterogéneo de neoplasias linfóides com diferentes apresentações, evoluções, prognósticos e tratamentos. Os LDGCB correspondem, dentro deste grupo, a neoplasias e células grandes e maduras, com uma grande taxa de proliferação. A classificação deste tipo de tumores, que inicialmente se prendia apenas com a apresentação clinica e morfológica da doença, tem sofrido alterações e aperfeiçoamento ao longo dos tempos, passando a englobar os perfis moleculares e imunológicos. As descobertas obtidas através desta melhor categorização, provaram ser importantes fatores de prognósticos, e com maior aplicabilidade na escolha de terapêutica adequada. Com esta dissertação, e apoiando-me num caso clínico de um paciente jovem com LDGCB do Serviço de Hematologia do Hospital de Santo António, pretendo explorar os novos desafios no tratamento destes linfomas e a importância da sua caraterização correta, e cada vez mais específica, uma vez que têm aplicabilidade na escolha e desenvolvimento de tratamentos.
THE CORRELATION OF SINGLE NUCLEOTIDE POLYMORPHISM IN OXYTOCIN AND OXYTOCIN RECEPTOR GENES AND THE SERUM OXYTOCIN LEVEL IN THE IRAQI MALE CHILDREN WITH AUTISM

The aim of the present study was to test the possible correlation between oxytocin (rs2770378) and oxytocin receptor (rs53576) polymorphisms with the level of oxytocin in association with the severity of social and cognitive dysfunctions in children with autism. The study was done on 60 males with autism who were recruited from the Pediatric Department at Al-Sader General hospital, Baghdad-Iraq between November 2014 and April 2015. The levels of oxytocin (OXT) were measured in the sera of 60 Iraqi autistic male patients, categorized as mild, moderate and severe (20 patients each) and compared with 26 age- and gender-matched control subjects. The genetic polymorphism OXT/rs2770378 and OXTR/rs53576 was detected by polymerase chain reaction Restriction fragment length polymorphism (PCR-RFLP) method. From the genetic work it was concluded that OXT/rs2770378 polymorphism showed to have an effect on the level of oxytocin in the autistic children that in turn may involve in the pathogenesis of autism. Whereas, OXTR/rs53576 polymorphism showed a non-significant association with autism in the studied children and no effect of this polymorphism was demonstrated on the level of oxytocin.
Cytotoxic Effects of Leaf Extracts of Some Thymus L. (Lamiaceae) Representatives Using In Vitro Human Blood Model

In the course of in vitro systems search for the toxicity screening of plant extracts, different cellular models have been applied to examine their adverse effects in our previous studies. In this study, the main aim was to assess the dose-dependent pro- and antioxidant potential of four species and one interspecific hybrid of Thymus genus sampled in the western part of Ukraine on human erythrocytes‘ model. For this purpose, we used 2-thiobarbituric acid reactive substances (TBARS) as a biomarker of lipid peroxidation used as an assessment of oxidative stress in erythrocytes‘ suspension after incubation with plant extracts in two doses (5 mg/mL and 0.5 mg/mL). An erythrocytes’ suspension at 1% hematocrit was incubated with 4 mM phosphate buffer (pH 7.4) (control) and pre-incubated with the extracts (5 mg/mL and 0.5 mg/mL, respectively) at 37 °C for 60 min. The treatment by extracts obtained from various plants belonging to the Thymus genus in dose 5 mg/mL increased the TBARS level as a biomarker of lipid peroxidation in the human erythrocyte suspension when compared to untreated erythrocytes. The most potent prooxidative effect was demonstrated by the dose-dependent. Further research is needed to determine the effects of the active compounds of various plants belonging to the Thymus genus on erythrocytes‘ metabolism.
Precoder Design Algorithm using Spatial Signal Synthesis with Multiple Antenna Subset Selection for Hybrid MIMO System

In this paper, a precoder design algorithm using spatial signal synthesis with selected multiple antenna subsets for hybrid multiple-input multiple-out-put (MIMO) systems is proposed. The hybrid MIMO systems are expected to be implemented in high frequency bands. To reduce power consumption and increase the bandwidth of a transmit signal, the resolution of phase shifters and the number of quantization levels in digital-analog (D/A) converters have to be limited. A baseband precoder needs to take the effect of quantization into account. On the other hand, when the number of transmit antennas is larger than that of receive antennas, spatial signal synthesis can be realized. The selection of antenna sets also needs to take the effect of quantization into account. In this paper, a transmit antenna selection scheme that improves the spectral efficiency by spatial signal synthesis with multiple antenna subsets is proposed. Numerical results obtained through computer simulation show that the proposed scheme with two antenna subsets of four transmit antennas and two receive antennas improves the spectrum efficiency by about 1.0 bit/s/Hz when the number of transmit and receive are 4.