Miracle-dz/UniFAR-FTUs huggingface dataset:
Application of the method of clustering educational content in a social network

Currently, modern social technologies are used by hundreds of millions of users, are available free of charge, attractive and interesting. The article discusses the possibility of the use of social networks to improve e-learning institution of higher education. Considering the large amount of information disseminated by university students on the social network, it is proposed to use methods of data clustering - k-means (k-means) in the article, to personalize the content of educational materials. The results of the research can be used by teachers and instructors of higher education institutions to improve the content of the e-course and personalize e-learning.
Protein Contact Map Prediction Based on ResNet and DenseNet

Residue-residue contact prediction has become an increasingly important tool for modeling the three-dimensional structure of a protein when no homologous structure is available. Ultradeep residual neural network (ResNet) has become the most popular method for making contact predictions because it captures the contextual information between residues. In this paper, we propose a novel deep neural network framework for contact prediction which combines ResNet and DenseNet. This framework uses 1D ResNet to process sequential features, and besides PSSM, SS3, and solvent accessibility, we have introduced a new feature, position-specific frequency matrix (PSFM), as an input. Using ResNet's residual module and identity mapping, it can effectively process sequential features after which the outer concatenation function is used for sequential and pairwise features. Prediction accuracy is improved following a final processing step using the dense connection of DenseNet. The prediction accuracy of the protein contact map shows that our method is more effective than other popular methods due to the new network architecture and the added feature input.
Signals in the quest for the Holy Grail: consumer ranking of nutritional claims in cereal based products

As a result of increased consumer consciousness, demand for healthier food products is raising. Consumers seek healthier versions of food products which they relate to reduced presence of unhealthy components or increased of healthy ones. Responding to this the food industry has enlarged the variety of products available and signalled the presence of substances using nutritional claims. However, an average consumer at the supermarket devotes just a few seconds selecting each product. In this context, consumers are only able or willing to process the information that attracts their attention or it is more important for them. This paper analyses how consumer rank different nutritional claims for two processed cereal products. Five claims were chosen to reflect the current market availability landscape and relate to both "healthy" (i.e. fibre) and "unhealthy" (i.e. fat) substances. We use a direct ranking preference method with data from a survey conducted to consumers in a Spanish region in 2017. Results show that the ranking of claims differs between the two products (pastries and biscuits) and across consumers. However, consumers prefer those signaling reduced presence of unhealthy nutrients above those highlighting the presence of healthy ones. Thus, policy to maximize impact of nutritional labelling should be product-specific.
Effects Of Auditors’ Culpability On Creative Accounting In Southwest Nigeria

The study examined the effects of auditors’ culpability on creative accounting in Southwest Nigeria. The study employed questionnaire to gather data from 66 managers and 66 accountants. The study was analysed with the use of descriptive statistics and One Way Analysis of Variance to test the hypotheses of the study. The study found that auditors’ culpability has no effect on creative accounting in private sector in Nigeria. The study revealed that that the reasons for statutory auditors engaging in creative accounting practices have effect on the practice of creative accounting in Nigeria. The study recommends that accountants should uphold high ethical standards and maintain integrity in all their professional dealings. Accountants should not allow personal prejudice or bias to override the principle of objectivity, transparency and due diligence in the profession. Auditors must not only develop questioning mind, skill for critical assessment of audit evidence but must also exercise these skills with reasonable care and diligence.
Effect of Different Temperatures on Flexural Cyclic Fatigue Resistance of 2Shape and OneShape Rotary Endodontic Instruments

Objectives: The aim of the present study was to evaluate the effect of the different temperatures on the flexural cyclic fatigue of 2 Shape and OneShape rotary endodontic files.Materials and Methods: Forty-rotary endodontic files were divided according to the type of instrument used and the surrounding temperature (n=10); 2Shape and OneShape rotary endodontic files rotated in a custom made simulated canal model block fixed to a beaker containing water with temperature adjusted to either 37 °C or 60 °C. Time was recorded from the beginning of rotation until the fracture was detected, then the number of cycles to failure (NCF) and the length of the fractured segment (FL) were evaluated. Two representative samples were photographed under scanning electron microscopy. Two-way Analysis of Variance (ANOVA) was used to study the effect of the type of instrument used and temperature on the number of cycles to failure and the length of the fractured segment. Results: 2Shape rotary endodontic files used at 37° C showed statistically significant highest mean of number of cycles to failure compared to 2Shape at 60°C (P<0.001), then OneShape used at 37°C, and finally the OneShape used at 60 °C (P<0.011). Conclusions: 2 Shape showed more resistance to flexural cyclic fatigue than OneShape, and high temperature seemed to have a reducing effect on the flexural cyclic fatigue resistance of the both tested rotary endodontic instruments. Objectives: The aim of the present study was to evaluate the effect of the different temperatures on the flexural cyclic fatigue of 2 Shape and OneShape rotary endodontic files.Materials and Methods: Forty-rotary endodontic files were divided according to the type of instrument used and the surrounding temperature (n=10); 2Shape and OneShape rotary endodontic files rotated in a custom made simulated canal model block fixed to a beaker containing water with temperature adjusted to either 37 °C or 60 °C. Time was recorded from the beginning of rotation until the fracture was detected, then the number of cycles to failure (NCF) and the length of the fractured segment (FL) were evaluated. Two representative samples were photographed under scanning electron microscopy. Two-way Analysis of Variance (ANOVA) was used to study the effect of the type of instrument used and temperature on the number of cycles to failure and the length of the fractured segment. Results: 2Shape rotary endodontic files used at 37° C showed statistically significant highest mean of number of cycles to failure compared to 2Shape at 60°C (P<0.001), then OneShape used at 37°C, and finally the OneShape used at 60 °C (P<0.011). Conclusions: 2 Shape showed more resistance to flexural cyclic fatigue than OneShape, and high temperature seemed to have a reducing effect on the flexural cyclic fatigue resistance of the both tested rotary endodontic instruments.
PROTECTIVE ROLE OF CARDIOSPERMUM HALICACABUM AGAINST THE CYPERMETHRIN TOXICITY IN THE OXIDATIVE STRESS IN THE FRESH WATER FISH CIRRHINUS MRIGALA (HAMILTON)

The effect of sublethal exposure of cypermethrin (30 μg/L) for 120 hours on varioues antioxidant enzymes was carried out in the freshwater fish Cirrhinus mrigala. The activity of antioxidant enzymes, such as superoxid dismutase (SOD), catalase (CAT), and giutothione peroxidase (GPx) were decreased, lipid peroxidation (LPO), was increased. This observation clearly indicates the defensive nature and the adaptive mechanism of cells against free radical induced toxicity, Cardiosperumum halicacabum in plant extracts may afford protection from pesticide toxicity.
The effect of polymorphism on active pharmaceutical ingredients: A review

Active pharmaceutical ingredients (API) are the main components in the production process of pharmaceutical products. If the API has a good quality, then it will lead to good pharmaceutical products. API consists of more than one different crystal form which, then forms a polymorph through the process of polymorphism. Until now, API polymorphism is still a big challenge in the pharmaceutical industry. That is because the nature of polymorphism is dif icult to predict. One of them is by crystallizing molecules in one or many crystalline formsor combiningwithothermolecules to formstable co-crystal. This process will lead to several polymorph forms of one certain API. Sometimes, these forms will have characteristics that differ one to another. Each polymorph has different mechanical, physical, thermal, and chemical properties that will affect the solubility, dissolution, bioavailability, stability, bioequivalence, and manufacturing of the API. Therefore to know the nature of an API, it is necessary to characterize the polymorphic form of the API before. If the form is not incompatiblewith the formulation, it can cause a failure in the production process. This review will discuss the effect of polymorphism on the physicochemical properties of API. It is hoped that this review can become the basis for improving the stability and effectiveness of pharmaceutical products.
Timely treatment in stroke and TIA

In acute stroke, the effect of both acute treatments and secondary prevention is timedependent. Patients ́ delay is an important obstacle to acute recanalization therapy for stroke. To decrease this delay, a stroke educational campaign was carried out in Sweden. After an ischemic event, the risk of early recurrent stroke is particularly high if the event is caused by a carotid stenosis. Urgent carotid endarterectomy (CEA) reduce the risk of recurrent stroke, but the optimal timing for CEA after a cerebrovascular event is not known because of uncertainties with respect to the procedural risk in very urgent CEA. The aim of this thesis was to investigate the effects of the stroke campaign, and to investigate the procedural risk of very urgent CEA. Study I, a study based on telephone interviews, evaluated public stroke knowledge and intent to call 112 before the stroke campaign. Seventy-two percent could report at least one stroke symptom and 65% indicated they would call 112 for stroke. Study II, a study based on telephone interviews, investigated the effect of the campaign on awareness of the AKUT (equivalent to the FAST, Face-Arm-SpeechTime) test and intent to call 112. Before the campaign started, 15% had heard about the AKUT test, compared with 51% during and directly after the campaign, and 50% 21 months later. Corresponding figures were 65%, 76% and 73% for intent to call 112. Study III, a prospective national study, evaluated the effect of the campaign on prehospital delay and recanalization therapy rate. During the campaign, but not the year before, nor the year after, the proportion arriving at hospital within three hours from stroke onset and the proportion receiving recanalization therapy increased significantly. Study IV, a prospective controlled study, compared the procedural risk in patients undergoing CEA < 48 hours with CEA 2-14 days from an ischemic event. Patients undergoing CEA < 48 hours from symptom onset had a higher risk of complications (stroke and/or death) compared with those operated on later, 8.0% versus 2.9%. In conclusion, public awareness of stroke was rather low in Sweden and was increased by the Swedish National Stroke Campaign. The campaign was also associated with a sustained increase in the proportion receiving recanalization therapy and with a small improvement of the proportion arriving at hospital within three hours. CEA < 48 hours was associated with a higher procedural risk compared with surgery 2-14 days after an ischemic event.
INTERACTIVE PLAYGROUND GAMES TO MOTIVATE PLAYING

Children with motor disorders have difficulties with fine and gross motor skills, which make it harder for them to perform a moderate-vigorous physical activity. Because it requires a lot of effort, children avoid doing physical activities outside of their rehabilitation sessions. Instead, they prefer to play video games, which are easier to master and make them feel competent. However, an increase in physical activity can help the children to overcome the difficulties associated with their disorder and improve their quality of life. Within this research two interactive playground games have been designed – a single player game and a multiplayer game. The games can be used in pediatric physiotherapy sessions as a tool to encourage patients with motor deficiencies to be physically active while playing, even outside the scope of the rehabilitation. Both games are inspired by and include the elements of the wellknown rock-paper-scissors game. Since the aim is also to inspire the children to play without technology, the multiplayer interactive playground game is transferable to a real-life setting. The games were tested in order to evaluate how successful they are in the context of promoting physical activity. The multiplayer interactive playground game was evaluated also for the value it gives to the real-life play. The results showed that the single player game triggers different physical movements like running, jumping and sliding on the floor. The multiplayer game, on the other hand, was not fully successful due to limitations in its implementation and the technology of the interactive playground. However, a between-subject experiment with experimental and control groups showed that the interactive playground game influences the play of the real-life game as it gives insights to the players for additional rules and game elements.
Increasing Studentsâ€™ Reading Comprehension Through Task-based Approach

Tujuan dari penelitian ini adalah untuk mengetahui apakah ada peningkatan signifikan pada prestasi pemahaman membaca siswa setelah diajar menggunakan pendekatan berbasis tugas. Populasi dari penelitian ini adalah siswa tahun pertama SMKN 2 Bandar Lampung yang terdiri dari 15 kelas dan satu kelas diambil sebagai kelas sampel. Sampel ini dipilih dengan menggunakan teknik random sampling. Penelitian ini merupakan penelitian kuantitatif dan menggunakan desain one group pretest- posttest. Skor rata-rata pretest adalah 51,43 dan skor rata-rata posttest adalah 78,43, jadi peningkatannya adalah 27,00. Nilai signifikan (2-tailed) adalah p= 0,000, dimana p< 0,05, hal ini menunjukkan bahwa hipotesis satu diterima. Dari lima aspek dalam membaca yang diamati, mengidentifikasi ide pokok merupakan yang paling meningkat dan siswa memiliki respon positif setelah diajar menggunakan pendekatan berbasis tugas. Maka disimpulkan bahwa pendekatan berbasis tugas secara signifikan dapat meningkatkan prestasi membaca pemahaman siswa. Â The objective of this research is to find out whether there is significant increase of studentsâ€™ reading comprehension achievement after being taught using task-based approach. The population of this research is the first year students of SMKN 2 Bandar Lampung consisting of 15 classes and one class is taken as the sample class. The sample is selected by using the random sampling technique. This is a quantitative research and one group pretest- posttest design was employed. The mean score of pretest is 51,43 and mean score of posttest is 78,43, so the increase is 27,00. The significant (2-tailed)Â value was p=0.000, where p< 0.05, it showed that the hypothesis was accepted. From five reading aspects being observed,Â identifying main idea was the most increased and students had positive respond after being taught using task-based approach. It was therefore concluded that task-based approach could significantly increase studentsâ€™ reading comprehension achievement.
Are business intelligence systems different to decision support systems and other business information systems?

A common view of information systems (IS) researchers is that business intelligence (BI) systems are essentially a type of decision support systems (DSS). This approach to knowledge implies that DSS theory can be transferred to BI systems in order to explain and predict their action. Further, some researchers feel that BI systems can also be adequately researched using general IS theory. This paper is the first from a project that is examining if BI systems have significant differences to operational IS and DSS. This first exploration is informed by a focus group of senior BI professionals. The study illuminates some differences between BI and other types of business IS and indicates that context could be significant for BI theorizing and that care is needed in transferring operational IS and DSS theory to BI systems research. In practice, these differences could be a source of project failure.
Synthesis and characterization of poly(N-isopropylmethacrylamide-co-N-isopropylacrylamide) copolymers

Copolymeric hydrogels of poly(N-isopropylmethacrylamide-co-N-isopropylacrylamide), p(NIPMAM/NIPAM), are synthesized by radical polymerization of N-isopropylmethacryl-amide (NIPMAM) and N-isopropylacrylamide (NIPAM) monomers by using the cross-linker ethylen glycol dimethacrylate (EGDM). The synthesized copolymeric p(NIPMAM/NIPAM) hydrogels, starting monomers and the cross-linker were structurally characterized by using Fourier transform infrared spectroscopy (FTIR). The amounts of residual reactants in the synthesized hydrogels were determined by high-pressure liquid chromatography (HPLC). Swelling of p(NIPMAM/NIPAM) hydrogels was investigated in relation to the temperature and pH value of the solution. The obtained values of residual monomer quantities are within acceptable limits and in the range from 2.69 to 5.25 mg g-1 for NIPMAM and 14.55 to 30.80 mg g-1 for NIPAM. The synthesized p(NIPMAM/NIPAM) hydrogels are negatively thermosensitive. The most common mechanisms of transport of a swelling solution in p(NIPMAM/NIPAM) hydrogels are polymer chain relaxation, (Case III), and the anomalous type of diffusion (non-Fickian diffusion). The maximal equilibrium swelling degree of 51.19 was reached by the p(NIPMAM/NIPAM) hydrogel with 1.5 mol% of EGDM at the temperature of 25? C and pH 4, whereas the lowest one of 0.98 was exhibited by the hydrogel with 3 mol% of EGDM at the temperature of 80? C and pH 7. Due to their low content of residual reactants and a satisfactory degree of swelling at various pH values, synthesized p(NIPMAM/NIPAM) hydrogels can be applied as carriers for the controlled release of pharmaceutically active substances.
The role of alpha and beta adrenergic receptors in cortisol-induced hyperglycaemia in the common African toad ( Bufo regularis )

The role of adrenergic receptors in cortisol-induced hyperglycaemia is not well known. The present study investigates the effects of adrenergic receptor blockers in cortisol-induced hyperglycaemia in the common African toad (Bufo regularis). Each toad was fasted and anesthetized with sodium pentobarbitone (3 mg/100 g i.p). The animals (control) received intravenous (i.v) injection of 0.7% amphibian saline while animals (untreated) were given cortisol (20 μg/kg). In pre-treatment groups, animals received prazosin (0.2 mg/kg i.v), propranolol 0.5 mg/kg or combination of prazosin (0.2 mg/kg i.v) and propranolol (0.5 mg/kg i.v) before i.v injection of cortisol (20 μg/kg). Thereafter, blood samples were collected for estimation of blood glucose level using the modified glucose oxidase method. Cortisol caused significant increase in blood glucose level from 44.4±3.8 to 71.7±9.7 mg/dl. Pretreatment of the toads with propranolol (0.5 mg/kg i.v) caused significant reduction (p≤ 0.01) in cortisolinduced hyperglycaemia while pre-treatment with prazosin (0.2 mg/kg i.v) produced no significant effect on hyperglycaemia induced by cortisol. The combination of both prazosin and propranolol completely abolished the effects of cortisol on blood glucose level. The results suggest that cortisol-induced hyperglycaemia in the toad (B. regularis) is mediated probably by both the α- and β-adrenergic receptors with the beta adrenergic receptors playing dominant role. Keywords: Cortisol, hyperglycaemia, prazosin, propranolol, amphibian saline, common African toad. African Journal of Biotechnology Vol. 12(36), pp. 5554-5558
Tailored interventions to assist smokers to stop smoking using e-cigarettes (TASSE): Study protocol

Background: There is increasing evidence that e-cigarettes (EC) are an effective smoking cessation aid when combined with behavioural support. There is further evidence for digital tailored interventions as cost effective approaches that can increase smoking cessation rates. Experimental work also suggests the addition of a ‘nicotine fact sheet’ can improve smokers’ risk perceptions related to EC. However, multifaceted approaches to deliver ‘tailored advice’ for smoking cessation combining various key evidenced based components are lacking. The aim of this study is to use a Multiphase Optimisation Strategy (MOST) to determine which of five, or a combination thereof, EC-orientated intervention components is associated with self-reported cessation over the previous 4-weeks at 12-week follow-up. Methods/Design: This online study will utilise a 2x2x2x2x2 factorial design resulting in 32 experimental conditions. The five intervention components will be: 1: tailored advice on EC device; 2: tailored advice on e-liquid nicotine strength; 3: tailored advice on e-liquid flavour; 4: e-cigarette written information; 5: text message support. A sample of N=1184 adult, UK resident smokers will be randomly allocated to one of the 32 conditions, which will be permutations of the 5 components (counter-balanced). The primary outcome is 4 weeks of self-reported complete abstinence at 12 weeks post randomisation. Secondary outcomes are 7-day point prevalence, 50% reduction in baseline cigarettes smoked per day, time to switch and adherence to recommendation. The primary analysis will be by intent-to-treat with the assumption that missing equals smoking. Logistic regression will be used to model the five main effects and the ten 2x2 interactions. A number of secondary analyses will also be conducted including models adjusting for demographic and smoking indices and including only those who received the intervention. Discussion: To date, components that assist quitting by use of EC or other aids have largely been studied in isolation. This study presents the first attempt to combine evidenced based interventions, using the MOST method, to test which components are associated with quitting. The findings will be used to inform which components to include and their estimated effect sizes for a definitive randomised controlled trial (RCT) to examine the efficacy of the intervention compared with usual care (own choice and no support). Keywords: Digital interventions; Tailored Advice; Smoking cessation; Smoking reduction; E-cigarettes; Multi-phase Optimisation Strategy (MOST); Tobacco; Nicotine; Vaping