Miracle-dz/UniFAR-FTUs huggingface dataset:
Weakness and Low Lean Mass in Women With Hip Fracture: Prevalence According to the FNIH Criteria and Association With the Short-Term Functional Recovery

Background and Purpose: People with hip fracture commonly have low muscle mass, reduced muscle strength, limited mobility, and limited ability to function in activities of daily living. Our aim was to assess the role of grip strength and appendicular lean mass (aLM) to predict the short-term functional recovery in women with hip fracture. For both strength and aLM, we focused on the cutoff points recently released by the Foundation for the National Institutes of Health (FNIH). Methods: In this short-term prospective observational study, we investigated 138 white women consecutively admitted to a rehabilitation hospital because of their first hip fracture. We measured aLM by dual-energy x-ray absorptiometry, grip strength with a hand dynamometer, and body mass index (BMI) at a median of 18 days after hip fracture occurrence. Functional autonomy was assessed by the Barthel index at the end of the rehabilitation course. Results: Fifty-five of the 138 women (40%; 95% confidence interval [CI], 32%-48%) had a handgrip strength less than 16 kg, whereas 33 (24%; 95% CI, 17%-31%) had a handgrip strength/BMI less than 0.56. In both cases, the weak women had Barthel index scores significantly lower than the nonweak women (P ⩽ .001). One hundred eighteen of the 138 women (86%; 95% CI, 80%-91%) had an aLM less than 15.02 kg, whereas 65 (48%; 95% CI, 39%-56%) had an aLM/BMI less than 0.512. In both cases the Barthel index scores were nonsignificantly different between the women whose aLM indexes were either below or above the cutoff points. Conclusions: Categorization according to the FNIH cutoff points for weakness significantly predicted the functional outcome in women with hip fracture, whereas categorization for aLM did not. Adjustments for BMI significantly changed the prevalence of either weakness or low aLM, but did not materially change their predictive roles.
Motiver les élèves en EPS au travers de son style d’enseignement

Les bienfaits de l’activite physique sur l’organisme sont aujourd’hui prouves et les recherches montrent que les habitudes en la matiere sont prises des le plus jeune âge. En tant qu’enseignant, l’enjeu est alors de developper le gout de cette pratique chez les eleves, mais comment arriver a les motiver en EPS? En m’appuyant sur la theorie de l’autodetermination, je m’interroge sur la relation existant entre un style d’enseignement soutenant l’autonomie (SA) en EPS et la motivation autodeterminee des eleves pour l’activite physique a l’ecole primaire. Dans cette etude, j’analyse donc mon propre style grâce a une grille d’observation afin d’evoluer vers plus de SA. Je mesure ensuite les consequences de ce changement sur la motivation autodeterminee des eleves, par questionnaire et observation. Les resultats montrent qu’en s’auto-formant sur le SA, un enseignant du primaire peut faire evoluer son style. Concernant les consequences de cette evolution sur la motivation des eleves, les resultats varient : ceux obtenus par questionnaire ne demontrent pas de lien marque. En revanche, ceux obtenus par observation revelent un accroissement de la motivation autodeterminee des eleves. Cette etude serait donc a prolonger pour valider ou non l’existence d’une correlation entre style de l’enseignant et motivation des eleves.
Hawking radiation from the quantum Lemaitre-Tolman-Bondi model

In an earlier paper, we obtained exact solutions of the Wheeler-DeWitt equation for the Lemaitre-Tolman-Bondi model of gravitational collapse, employing a lattice regularization. In this paper, we derive Hawking radiation in nonmarginally bound models from our exact solutions. We show that a nonvanishing energy function does not spoil the (approximate) Planck spectrum near the horizon. We can also reliably compute corrections to the Bogoliubov coefficient because our solutions are exact. The corrections are obtained by going beyond the near-horizon region and are shown to introduce additional greybody factors, which modify the blackbody spectrum of radiation from the black hole.
Spinal cord MRI in multiple sclerosis with multicoil arrays: a comparison between fast spin echo and fast FLAIR.

OBJECTIVES: To compare the sensitivity of fast spin echo (FSE) and of fast fluid attenuated inversion recovery (fast FLAIR) in detecting spinal cord lesions in multiple sclerosis. METHODS: With a 1.5 Tesla machine and a multicoil receiver array, FSE images (with two different pixel sizes) and fast FLAIR images of the spinal cord were obtained from 13 patients with multiple sclerosis. RESULTS: Twenty three lesions (10 cervical, 12 thoracic, and one lumbar) were found in seven patients (54%) using FSE with the larger pixel size. Seventeen lesions (seven cervical and 10 thoracic) were detected in the same seven patients using FSE with smaller pixel size. Nine lesions (five cervical and four thoracic) were found using fast FLAIR in six patients (46%). All the lesions found using fast FLAIR were detected using the other two techniques and all the lesions detected by FSE with smaller pixel size were detected using FSE and greater pixel size. CONCLUSION: Fast FLAIR sequences detect substantially fewer cord lesions in patients with multiple sclerosis.
Modelo para estimar a geração de resíduos na produção de obras residenciais verticais

A significativa quantidade de residuos gerada pelo setor da construcao civil e hoje um grande problema ambiental a ser enfrentado pelo poder publico e empresas construtoras. Para evitar ou reduzir a geracao de residuos e preciso atuar na origem, que pode estar desde o projeto ate a fase de execucao. O projeto consiste no passo inicial do empreendimento e tem influencia significativa sobre o processo construtivo e produto final. Estudos apontam tambem que o sistema de gestao empregado por construtoras tem relacao direta com a ocorrencia de perdas, incluindo os residuos. O conhecimento do indice de geracao de residuos e uma importante informacao gerencial, com diferentes objetivos, desde a conscientizacao do problema, ate para servir de base para o planejamento e implementacao de acoes voltadas a minimizacao da geracao. Contudo, a quantificacao dos residuos de construcao ainda pode ser considerada como um desafio, tendo em vista caracteristicas peculiares da construcao e a heterogeneidade dos residuos. Observa-se muita variabilidade nos metodos empregados e variaveis consideradas, alem das diferencas relativas a epoca e contextos pesquisados para geracao dos indices e indicadores. Este trabalho propoe o desenvolvimento de um modelo estatistico para estimar a quantificacao da geracao de RCD em obras residenciais verticais, considerando caracteristicas especificas das construtoras que atuam na regiao metropolitana de Porto Alegre-RS, investigando a influencia do projeto e do sistema de producao. A estrategia de pesquisa consistiu num estudo de caso com multiplas fontes de evidencias, utilizando como ferramenta de analise estatistica a regressao linear multipla. A amostra e formada por dados de 20 obras residenciais verticais de 10 empresas que atuam na regiao metropolitana de Porto Alegre. Como resultado foi gerado um modelo estatistico, formado pela variavel dependente (estimativa da quantidade de residuo a ser gerada) e variaveis independentes relativas ao projeto (area do pavimento tipo, relacao entre o numero de pavimentos tipos e o numero total de pavimentos e Indice economico de compacidade) e ao sistema de producao (sistema construtivo e reaproveitamento de residuos no canteiro). O modelo proposto obteve valor de R² ajustado = 0,69, permitindo explicar 69% da geracao de residuos em obras com caracteristicas semelhantes, foi observada melhor aproximacao da estimativa realizada pelo modelo quando comparado a algumas estimativas da literatura. A informacao gerada atraves do modelo e importante na conscientizacao dos empresarios locais e util para basear acoes no sentido de minimizar a geracao, reciclar ou acoes relativas ao destino final adequado, alem de possibilitar comparacoes com informacoes sobre a geracao de residuos de outras localidades.
Liposomes for targeted drug delivery

MUC-1 aptamer-amphiphiles were used to functionalize DPPC liposomes to create nanoparticles. Various properties of the targeted liposomes drug delivery vehicles were examined including their drug-to-lipid ratio (DL), targeted ligand insertion efficiency (IE), and stability. The ratio of lipid and MUC-1 aptamer-amphiphile in the liposomes was varied to determine this ratio’s influence on liposomal drug-to lipid ratio, insertion efficiency, and stability. We found that the insertion efficiency and drug-to-lipid ratio is unaffected by the presence of targeting ligand, with a maximum insertion efficiency of 85.4% for the targeted liposomes. The amount of drug loaded into targeted and non-targeted liposomes ranged from 0.10 mg per 1 mg lipids to 0.22 mg per 1 mg lipid. The liposomal leakage was found to be small over the course of 4 days for both targeted and nontargeted liposomal formulations, but there was a 50% increase in leakage in the presence of targeting ligand. The liposomal leakage was lower than 10% for 37°C and 5% in 4°C.
Polymorphisms associated with thrombophilia and vascular homeostasis and the timing of menarche and menopause in 728 white women

Objective:Genetic factors have been proposed as modulators of the timing of natural menopause. Single nucleotide polymorphisms (SNPs) of genes associated with thrombophilia and vascular homeostasis may interfere with ovarian function and thus are candidate genes for early menopause. We attempted to assess the association of SNPs and the timing of menarche and natural and surgical menopause in an ethnically homogenous cohort of Middle European white women. Design:In the present cross-sectional study, eight SNPs of six genes involved in vascular function and homeostasis were analyzed by sequencing-on-chip using solid-phase polymerase chain reaction on oligonucleotide microarrays in 728 white women: factor V (F5) Leiden G1691A, factor II (F2) prothrombin G20210A, plasminogen activator inhibitor1 (PAI-1) 4G/5G, angiotensinogen (AGT) Met235Thr, endothelial nitric oxide synthase (NOS3) T768C and NOS3 Glu298Asp, apolipoprotein E-1 (APOE-1) Cys112Arg, and APOE-2 Arg158Cys. The women's reproductive and medical histories were correlated to genotypes. Results:In a univariate analysis, current smoking (P = 0.01) and the presence of at least one mutant allele of F5 Leiden (P = 0.03) and APOE-2 (P = 0.03) were significantly associated with a reduced age at natural menopause. The presence of at least one mutant allele of F5 Leiden (P = 0.02) and a body mass index above 25 kg/m2 (P = 0.009) were significantly associated with an increased risk for surgical menopause by premenopausal hysterectomy (odds ratio = 2.6, 95% CI, 1.2-5.6; odds ratio = 1.9, 95% CI, 1.2-3.0, respectively). Age at menarche was not affected by the carriage of any of the investigated SNPs. Applying stepwise linear regression models considering all two-way interactions, no interactions were found among different SNPs or between SNPs and environmental and lifestyle parameters. Conclusion:We identified various genetic and personal history parameters influencing age at natural menopause and the risk of undergoing premenopausal hysterectomy. To the best of our knowledge, we present the largest study to date determining SNPs as contributors to the genetic control of the timing of natural and surgical menopause.
Implementation and Evaluation of EduBingo for Arithmetic Drill

Bingo is a universally known, popular, and easy-to-play game. Following bingo rules with some modifications, we have designed and implemented a game, called EduBingo, for practicing mathematics fractions. The game was implemented and experimented in a 'one-to-one' technology enhanced classroom, where every student learns with a wireless enabled computing device. The experiment investigated students' preferences, system usability, as well as the effects on their affective states of a grade 4 class with 22 students. The result of the questionnaire indicates that the usability of EduBingo is acceptable and there was increase of various affective levels of the students. The data collected by the system, after analysis, implies that, for most students, accuracy and efficiency of solving fraction questions increased. The preliminary result also suggests some directions for further research.
Convergence of Prox-Regularization Methods for Generalized Fractional Programming

We propose an approximate analysis of open systems of tandem queues with blocking caused by finite buffers between servers. Our approach relies on the use of marginal probability distributions (“state equivalence”) coupled with an approximate evaluation of the conditional probabilities introduced through the equivalence. The method iterates over consecutive pairs of servers using the solution of a two-queue system as a building block. It produces performance measures for individual servers as well as an approximation to joint queue-length probability distributions for pairs of neighboring stations. Experience indicates that the number of iterations required for the method grows moderately with the number of nodes in the network. We give examples to demonstrate the accuracy and the convergence properties of the proposed approximation.
Studies of the Large-Scale Structure in Turbulent Boundary Layers Using Simultaneous Velocity-Wavefront Measurements

Simultaneous velocity field and optical distortions along the wall-normal direction were performed in a subsonic boundary layer. Comparison between wavefronts and the ones predicted using instantaneous Strong Reynolds Analogy had shown that instantaneous SRA is valid most of the time. Conditional velocity analysis had shown that positive OPD distortions are created by predominantly ejection-type Q2 events near the wall and overall uv-Reynolds shear stress is larger near the wall and smaller away from the wall. The negative distortions are mostly due to sweep-type Q4 events near the middle of the boundary layer, with significantly larger uv-Reynolds shear stress throughout the boundary layer. Conditional velocity fields during the events, where the instantaneous SRA failed to predict optical distortions, were extracted and analyzed and possible reasons for these differences are presented and discussed.
Phylogeny of Anophelinae using mitochondrial protein coding genes

Malaria is a vector-borne disease that is a great burden on the poorest and most marginalized communities of the tropical and subtropical world. Approximately 41 species of Anopheline mosquitoes can effectively spread species of Plasmodium parasites that cause human malaria. Proposing a natural classification for the subfamily Anophelinae has been a continuous effort, addressed using both morphology and DNA sequence data. The monophyly of the genus Anopheles, and phylogenetic placement of the genus Bironella, subgenera Kerteszia, Lophopodomyia and Stethomyia within the subfamily Anophelinae, remain in question. To understand the classification of Anophelinae, we inferred the phylogeny of all three genera (Anopheles, Bironella, Chagasia) and major subgenera by analysing the amino acid sequences of the 13 protein coding genes of 150 newly sequenced mitochondrial genomes of Anophelinae and 18 newly sequenced Culex species as outgroup taxa, supplemented with 23 mitogenomes from GenBank. Our analyses generally place genus Bironella within the genus Anopheles, which implies that the latter as it is currently defined is not monophyletic. With some inconsistencies, Bironella was placed within the major clade that includes Anopheles, Cellia, Kerteszia, Lophopodomyia, Nyssorhynchus and Stethomyia, which were found to be monophyletic groups within Anophelinae. Our findings provided robust evidence for elevating the monophyletic groupings Kerteszia, Lophopodomyia, Nyssorhynchus and Stethomyia to genus level; genus Anopheles to include subgenera Anopheles, Baimaia, Cellia and Christya; Anopheles parvus to be placed into a new genus; Nyssorhynchus to be elevated to genus level; the genus Nyssorhynchus to include subgenera Myzorhynchella and Nyssorhynchus; Anopheles atacamensis and Anopheles pictipennis to be transferred from subgenus Nyssorhynchus to subgenus Myzorhynchella; and subgenus Nyssorhynchus to encompass the remaining species of Argyritarsis and Albimanus Sections.
Impact du statut socio-économique sur le comportement et les performances scolaires des enfants scolarisés au Maroc

Parmi les facteurs principaux qui paraissent determiner le cursus scolaire de l’enfant on cite principalement l’environnement socio-economique. L’objectif de cette etude est d’etudier l’effet des facteurs socio-economiques sur les performances scolaires des enfants âgees de 6 a 14 ans d’une ecole public primaire dans la province d’AZILAL (Maroc). Les informations concernant ces enfants sont collectees en utilisant un questionnaire enregistrant l’âge, les mesures anthropometriques, les facteurs socioeconomiques aussi que l’appreciation des determinants des performances scolaires et comportementales de l’individu. Pour chaque determinant, l'echantillon enquete a ete groupe en deux afin d'adopter une etude comparative. Le traitement des resultats a ete fait en utilisant le logiciel SPSS version 20. Les resultats montrent qu’il existe une dependance significative entre l’assiduite et le comportement dans les activites scolaires d’une part et le niveau d’instruction du pere d’une autre part (p<0,05). Les resultats montrent aussi qu’il y a une dependance significative entre l’assiduite et le revenu du menage (CHI2= 14,80). Les facteurs socio-economiques etudies influencent negativement sur l’aptitude de l’eleve a progresser dans son parcours scolaire.
Face Basosquamous Carcinoma, a Case Report

Face basosquamous or metatypical carcinoma is a rare and controversial form of skin cancer. It is characterized by increased incidence of recurrence and distant metastases. We present the case of a patient of 71 years with an ulcerative lesion of 3/4 cm in the nasal pyramid. The injury occurred due to trauma to the nasal pyramid, produced 13 years ago. After investigation, which included ORL examination, imaging and oncology exam, surgery was decided to completely ablate tumor formation. The resulted defect of 4/5 cm was covered by mobilizing a forehead flap based on right supratrohleare artery pedicle. Histopathological examination revealed the diagnosis of basosquamous or metatypical carcinoma. The patient was referred to the oncology service for treatment.
DOSE RESPONSE RELATIONSHIP FOR CISPLATIN INDUCED MICRONUCLEI IN BONE MARROW ERYTHROCYTES OF SWISS ALBINO MICE

Cis - Dichlorodiamminoplatinum - II (Cis - DDP) has been widely as anticancer chemotherapertic agent. The genotoxicity of CIs - DDP was investigated in in vivo mice system using micronucleus test in bone marrow erythrocytes of mice. Various doses of cisptatin i.e., 2.5, 5 and 10 mg/kg were selected based on thearapertic concentration. The animals were scarified 6h after the last treatment and smears were stained with Giemsa May Grunwald stain. The prepared slides were screened for the presence of micronuclei in polychromatic erythrocytes of mice. A significant increase in the frequency of micronuclei in poly chromatic erythrocytes was noted when compared with control values.
Reduced expression of transforming growth factor‐β receptors is an unfavorable prognostic factor in human esophageal squamous cell carcinoma

Transforming growth factor‐β (TGF‐β) inhibits epithelial cell proliferation. Inactivation of the TGF‐β signaling pathway is thought to play a role in tumorigenesis. Our purpose was to clarify the correlation between TGF‐β receptors or TGF‐β1 expression and the clinicopathologic characteristics of patients with esophageal squamous cell carcinoma (SCC). Immunohistochemical staining for TGF‐β type I receptor (TGF‐βR‐I), TGF‐βR‐II and TGF‐β1 was performed on surgical specimens obtained from 80 patients with esophageal SCC. Preoperative plasma TGF‐β1 levels were measured and correlated with pathologic features and clinical outcomes. Expression of TGF‐βR‐I and TGF‐βR‐II was reduced in 43 (53.8%) and 23 (28.8%) specimens, respectively. TGF‐β1 was overexpressed in 29 (36.3%). Reduced expression of TGF‐βR‐I and TGF‐βR‐II showed a significant association with depth of invasion (p = 0.0015 and p = 0.0012), lymph node metastasis (p = 0.0309 and p = 0.0059) and pathologic stage (p = 0.0103 and p = 0.0401). Overexpression of TGF‐β1 had a significant association with depth of invasion only (p = 0.0335). Reduced expression of TGF‐βR‐I and TGF‐βR‐II was correlated with cancer‐specific survival (p = 0.0324 and p = 0.0243). The mean preoperative plasma TGF‐β1 level was 10.5 ± 0.8 ng/ml in patients with esophageal carcinoma and was significantly higher compared to healthy controls (p < 0.01). We demonstrate that reduced expression of TGF‐β receptors in esophageal SCC appears to be correlated with depth of invasion, lymph node metastasis, pathologic stage and poor prognosis. TGF‐β receptor expression may play a key role in the progression of this cancer. © 2003 Wiley‐Liss, Inc.
Awareness of Visual Inspection with Acetic-Acid (VIA) In Cervical Cancer Screening Among Nurses in Kaduna - State, Nigeria

The study aims at assessing the awareness of visual inspection with acetic-acid in cervical cancer screening among health workers in secondary health care institutions of Kaduna state. An Ex-post facto design was used for the study. The study population comprises all nurses, midwives, and nurse-midwives working in all the secondary healthcare institutions of the state. The sample size used for the study was 300 using the Yamane sample size selection formula. The technique involved was stratified sampling method whereby the three existing senatorial zones served as strata. Each of the stratum was clustered according to the existing local government areas. A purposive sampling was further used to select nine local governments, three from each senatorial zone that have secondary health care institutions. A proportionate sampling was used to distribute questionnaire copies to the health workers. The instruments used for data collection was a questionnaire which was structured base on a modified likert scale to four point scale. Three hundred (300) questionnaire copies were administered out of which (297) were retrieved. The data collected was analyzed using one way analysis of variance (ANOVA) and two sample t- test at 0.05 level of confidence to answer the hypothesis. Findings from the study shows that nurses in secondary healthcare institutions of Kaduna-state are not aware of using VIA in cervical cancer screening with an aggregate mean score of (2.2288). There is significant difference in the demographic variables of ( age-group, sex, professional category, and secondary health care institutions) in the awareness of VIA among nurses in Kaduna-state(p<0.05). It was therefore recommended that the state hospitals management board in collaboration with the Nursing and Midwifery Council of Nigeria should mount awareness campaign for nurses through seminars and workshops to make them fully aware of the VIA.
A review of microwave metamaterial structures classifications and applications

A review of articles and monographs on metamaterials are fulfilled in this paper in order to summarize the main types of artificial composites, depending on a sign of a permittivity and permeability. The classification of basic metamaterial structures for microwave applications with their characteristic properties and features is offered. Main disadvantages of the first metamaterial structures and ways of overcoming them are examined. Main approaches to design composite metamaterial structures with double-negative material properties are summarized and their distinctive features are considered. As well, relevance and applicability of such structures in microwave engineering are discussed with giving examples of these concepts in practical applications, particularly in waveguides and antennas technologies.