Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessing early communication behaviours: structure and validity of the Communication and Symbolic Behaviour Scales-Developmental Profile (CSBS-DP) in 12-month-old infants.

BACKGROUND Parent report instruments are frequently used for the identification of both 'at-risk' children and to support the diagnosis of communication delay. Whilst the evidence is strong for the accuracy of parent report of vocabulary between 2 and 3 years, there are fewer studies that have considered the ability of parents to report on early communication behaviours in 12-month-old infants. AIMS To investigate the validity of the underlying structure of the Communication and Symbolic Behaviour Scales-Developmental Profile (CSBS-DP) for each of the direct observation and parent reports of communication behaviour in infants at 12 months of age. METHODS & PROCEDURES Participants were 1725 infants, already participating in a longitudinal study of language development, whose parents completed the Infant-Toddler Checklist from the CSBS-DP. Seven hundred and twenty-eight (728) of these infants also completed the Behaviour Sample from the CSBS-DP. The structure of the CSBS-DP was examined using confirmatory factor analyses (CFA) of the Behaviour Sample and the Infant-Toddler Checklist. Correlations between the Infant-Toddler Checklist and the Behaviour Sample on the total, composite, and subscale scores were also calculated. OUTCOMES & RESULTS Confirmatory factor analysis of the CSBS-DP Behaviour Sample replicated previous work conducted during the development of the instrument, but on a larger and younger cohort of Australian infants. The data provided support for at least three factors, broadly representing Social, Speech, and Symbolic communication skills, with some evidence that the speech factor could be further split into sub-factors representing Sounds and Words. There was support for a three-factor structure for the Infant-Toddler Checklist. Moderate correlations were found between results from the Behaviour Sample and the Infant-Toddler Checklist. CONCLUSIONS & IMPLICATIONS As measures of early communication skill for young infants, the CSBS-DP Behaviour Sample and the Infant-Toddler Checklist are valid clinical tools for measuring constructs broadly representing Social, Speech, and Symbolic communication skills. The Speech composite in particular emerged as a strong factor under the Behaviour Sample.
Preterm Resuscitation With Low Oxygen Causes Less Oxidative Stress, Inflammation, and Chronic Lung Disease

OBJECTIVE: The goal was to reduce adverse pulmonary adverse outcomes, oxidative stress, and inflammation in neonates of 24 to 28 weeks of gestation initially resuscitated with fractions of inspired oxygen of 30% or 90%. METHODS: Randomized assignment to receive 30% (N = 37) or 90% (N = 41) oxygen was performed. Targeted oxygen saturation values were 75% at 5 minutes and 85% at 10 minutes. Blood oxidized glutathione (GSSG)/reduced glutathione ratio and urinary o-tyrosine, 8-oxo-dihydroxyguanosine, and isoprostane levels, isofuran elimination, and plasma interleukin 8 and tumor necrosis factor α levels were determined. RESULTS: The low-oxygen group needed fewer days of oxygen supplementation (6 vs 22 days; P < .01) and fewer days of mechanical ventilation (13 vs 27 days; P < .01) and had a lower incidence of bronchopulmonary dysplasia at discharge (15.4% vs 31.7%; P < .05). GSSG/reduced glutathione × 100 ratios at day 1 and 3 were significantly higher in the high-oxygen group (day 1: high-oxygen group: 13.36 ± 5.25; low-oxygen group: 8.46 ± 3.87; P < .01; day 3: high-oxygen group: 8.87 ± 4.40; low-oxygen group: 6.97 ± 3.11; P < .05). Urinary markers of oxidative stress were increased significantly in the high-oxygen group, compared with the low-oxygen group, in the first week after birth. GSSG levels on day 3 and urinary isofuran, o-tyrosine, and 8-hydroxy-2′-deoxyguanosine levels on day 7 were correlated significantly with development of chronic lung disease. CONCLUSIONS: Resuscitation of preterm neonates with 30% oxygen causes less oxidative stress, inflammation, need for oxygen, and risk of bronchopulmonary dysplasia.
IT capabilities and firm performance: An empirical research from the perspective of organizational decision-making

Based on resourced-based theory, this study tries to examine how IT capabilities affect firm performance. In contrast to past studies that have assumed that IT capabilities have direct effects on firm performance, this study argues that a firmpsilas performance can be explained by how effective the firm is in using IT to support organizational decision-making. A conceptual model is developed to explain the influencing mechanism of IT capabilities on firm performance. Several hypotheses are formulated to show the relationship among IT capabilities, organizational decision-making, and firm performance. Above model is empirically tested using data collected from 178 manufacturing firms in China. The results show that IT capabilities have positive effects on organizational decision-making, and organizational decision-making has positive effects on firm performance, and organizational decision-making has significant mediating effects on the relationship between IT capabilities and firm performance.
Detection and Identification of Explosive Particles in Fingerprints Using Attenuated Total Reflection‐Fourier Transform Infrared Spectromicroscopy

Abstract: The application of attenuated total reflection (ATR)‐Fourier transform infrared (FTIR) spectromicroscopy for detection of explosive particles in fingerprints is described. The combined functions of ATR‐FTIR spectromicroscopy are visual searching of particles in fingerprints and measuring the FTIR spectra of the particles. These functions make it possible to directly identify whether a suspect has handled explosives from the fingerprints alone. Particles in explosive contaminated fingerprints are either ingredients of the explosives, finger residues, or other foreign materials. These cannot normally be discriminated by their morphology alone. ATR‐FTIR spectra can provide both particle morphology and composition. Fingerprints analyzed by ATR‐FTIR can be used for further analysis and identification because of its non‐destructive character. Fingerprints contaminated with three different types of explosives, or potential explosives, have been analyzed herein. An infrared spectral library was searched in order to identify the explosive residues. The acquired spectra are compared to those of finger residue alone, in order to differentiate such residue from explosive residue.
Checking account activity and credit default risk of enterprises: An application of statistical learning methods

The existence of asymmetric information has always been a major concern for financial institutions. Financial intermediaries such as commercial banks need to study the quality of potential borrowers in order to make their decision on corporate loans. Classical methods model the default probability by financial ratios using the logistic regression. As one of the major commercial banks in France, we have access to the the account activities of corporate clients. We show that this transactional data outperforms classical financial ratios in predicting the default event. As the new data reflects the real time status of cash flow, this result confirms our intuition that liquidity plays an important role in the phenomenon of default. Moreover, the two data sets are supplementary to each other to a certain extent: the merged data has a better prediction power than each individual data. We have adopted some advanced machine learning methods and analyzed their characteristics. The correct use of these methods helps us to acquire a deeper understanding of the role of central factors in the phenomenon of default, such as credit line violations and cash inflows.
B cells alter the phenotype and function of follicular‐homing CXCR5+ T cells

The CXC chemokine receptor (CXCR)5 is rapidly induced on activated CD4+ T cells, allowing migration toward secondary lymphoid tissue follicles, where the CXCR5 ligand CXCL13/BCA‐1 is produced. Such CXCR5+ T cells provide efficient help for B cell immunoglobulin production and are termed follicular B helper T (TFH) cells. However, the molecular mechanisms by which TFH cells provide B cell help are unknown. Here, we demonstrate that newly generated (antigen‐primed) TFH cells express a phenotype consistent with induction of B cell proliferation, but co‐culture with primed B cells resulted in a switch to a plasma cell‐inducing phenotype, characterized by loss of CD154, induction of CD70 and an increase in IL‐10 production capacity. The ability to produce IL‐10 could be maintained as a stable phenotype, but its secretion was strictly dependent on inducible costimulator (ICOS) signaling. Furthermore, B cells preserved a lymph node migration phenotype in proliferating TFH cells by preventing the loss of CC chemokine receptor (CCR)7 and the induction of CCR5. Thus, B cells directly modulate the B cell helper phenotype in TFH cells and actively promote their prolonged co‐localization with these cells.
Solidification Studies of Polyethylene Glycols, Gelucire 44/14 or their Dispersions with Triamterene or Temazepam

The solidification of polyethylene glycols (PEG 1500, PEG 2000, PEG 4000, PEG 6000), gelucire 44/14 or their dispersions containing triamterene or temazepam were studied to assess the feasibility of using these dispersions to liquid‐fill hard gelatin capsules.
Nonlinear partial feedback linearizing controller design for grid-connected fuel-cell system with third harmonic injected PWM approach

The partial feedback linearizing controller design approach is presented in this paper, for a proton exchange membrane fuel-cell (PEMFC)-based energy storage system. The PEMFC system is connected to the three-phase grid through a voltage source converter (VSC). The dynamical model of the PEMFC is developed from the electrical equivalent circuit, and then based on the developed model partial feedback linearizing controller is employed to regulate the active and reactive power injection from the PEMFC system to the three-phase grid supply point. The dq-axes components of the grid current corresponding to the active and reactive power are controlled to accomplish the control objective. The partial feedback linearizing controller is implemented after investigating stability of the internal dynamics of grid-connected PEMFC system, as stable internal dynamics are crucial for the implementation of this type of controller. Third harmonic injected (THI) modulation scheme is incorporated with the partial feedback linearizing controller to increase efficiency of the controller. Finally, the performance of the proposed control approach is validated through simulation results under different grid events in a three-phase grid-connected PEMFC system, and in the CIGRE low voltage distribution network.
Unsupervised adaptation for deep neural network using linear least square method

In this paper, we propose a novel model based adaptation for deep neural networks based on a linear least square method. Our proposed algorithm can perform unsupervised adaptation even if the auto transcripts may have 60-70% of word error rate. We evaluate our algorithm on low resource languages, from the the IARPA BABEL program, such as Assamese, Bengali, Haitian Creole, Lao and Zulu. Our experiments focus on unsupervised speaker, dialect and environment adaptation and we show that it can improve both speech recognition and keyword search performance.
Performance of mobile OFDM systems over time-varying non-linearities with memory

The performance of modern communications transmitters utilizing multi-carrier modulation techniques is highly sensitive to non-linear distortions arising mainly from the highpower amplifier (HPA). The increase in symbol duration makes the system more sensitive to time-varying channels. In addition, the wideband characteristics of multi-carrier signals result in frequency-dependent distortions, typically know as memory effects. This paper presents analytical expressions that could be used to evaluate the impact of the distortions induced by time-varying non-linearities with memory on the BER performance of a multi-carrier signal such as the orthogonal frequency division multiplexing (OFDM). The time-varying non-linearity with memory is modeled by a time-varying Volterra Series. The resulting mathematical expressions are applied to an specific situation, allowing for a quantitative evaluation of the system performance degradation.
Caveolin-1 expression as a prognostic marker in triple negative breast cancers of Asian women

Background Triple-negative breast cancers (TNBCs) are defined by their lack of oestrogen receptor, progesterone receptor and epidermal growth factor receptor 2. Although heterogeneous, the majority are aggressive and treatment options are limited. Caveolin acts as tumour suppressor or promoter depending on the cancer type. Aim In this study, we aimed to determine if the expression levels of the candidate biomarker caveolin-1 on stromal or tumour cells were associated with clinicopathological parameters and disease outcomes in TNBCs from an ethnically diverse cohort of Asian women. Methods Tumour specimens from 699 women with TNBC were subjected to immunohistochemical analysis of the frequency and intensity of caveolin-1 expression in tumour and stromal cells. A subset of 141 tumour samples also underwent Nanostring measurement of CAV1 mRNA. Results were correlated with clinicopathological parameters and disease outcomes. Results Expression of caveolin-1 in stromal cells was observed in 14.4% of TNBC cases. TNBCs of the basal-like phenotype (85% of samples) were significantly more likely to exhibit stromal cell caveolin-1 expression (p=0.028), as were those with a trabecular growth pattern (p=0.007). Lack of stromal caveolin-1 expression in both TNBCs and those with the basal-like phenotype was significantly associated with worse overall survival (p=0.009 and p=0.026, respectively): accordingly, increasing mRNA levels of CAV1 in TNBC samples predicted better overall survival. Caveolin-1 expression on TNBC tumour cells was not associated with clinical outcome. Conclusion Stromal, but not tumoural, caveolin-1 expression is significantly associated with survival in Asian women with TNBC.
Why are urban Indian 6th graders using more tobacco than 8th graders? Findings from Project MYTRI

Objective: To investigate why urban Indian 6th graders may be using more tobacco than urban Indian 8th graders. Design: Cross-sectional survey of students conducted in the summer of 2004, as the baseline evaluation tool for a group-randomised tobacco prevention intervention trial (Project MYTRI). Mixed-effects regression models were used to (1) examine the relationship between 15 psychosocial risk factors and current use of any tobacco, by grade; and (2) examine differences in psychosocial risk factors, by grade. Setting: Thirty-two private (high socioeconomic status (SES)) and government (low-mid SES) schools in two large cities in India (Delhi and Chennai). Subjects: Students in the 6th and 8th grade in these schools (n = 11642). Among these, 50.6% resided in Delhi (v Chennai), 61.4% attended a government school (v a private school), 52.9% were enrolled in 6th grade (v 8th), and 54.9% were male (v female). Main outcome measure: Current (past 30 day) use of any tobacco, including chewing tobacco (for example, gutkha), bidis, or cigarettes. Result: Almost all psychosocial factors were significantly related to tobacco use, for students in both grades. Some of the strongest correlates included social susceptibility to and social norms about use. Exposure to tobacco advertising was a strong correlate of tobacco use for 6th graders, but not for 8th graders. Sixth graders scored lower than 8th graders on almost all factors, indicating higher risk. Conclusions: The “risk profile” of 6th graders suggests they would be vulnerable to use and to begin using tobacco, as well as to outside influences that may encourage use.
Minimal Hepatic Encephalopathy: Follow-Up 10 Years After Successful Liver Transplantation

Background. The long-term effect of liver transplantation (LT) on cognitive functions and the complete reversibility of minimal hepatic encephalopathy are poorly documented. Much evidence indicates that spatial attention improves starting from the immediate period after LT. However, at least in the first 2 years, some cognitive defects seem to persist to some degree, especially for supramodal nonverbal cognitive functions. The aim of this study is to investigate (i) whether the improvements observed in the perioperative period fluctuate or remain stable 10 years after LT and (ii) whether the functions that have been found defective also improve. Methods. We called patients previously included in a prospective study (Mattarozzi et al., Arch Neurol 2004; 61: 242) for a further neuropsychological evaluation. We compared the cognitive evaluation after 7 to 10 years with previous data gathered 6 and 18 months after LT. Results. The improvements obtained in the first 2 years after transplantation remain stable during the 7 to 10 years thereafter, especially for visuospatial attention, F(12,96) 1.70; P=0.04 and selective attention, F(6,66) 3.51; P=0.005. Furthermore, these findings also seem to suggest an improvement in supramodal cognitive functions, such as spatial planning intelligence, measured by the Elithorn Maze Test, F(3,33) 7.42; P=0.002. Verbal short-term memory, F(3,33) 3.69; P=0.038, and visuospatial short-term memory, F(6,64) 2.97; P=0.013, show a more fluctuating trend over time. Conclusions. Despite the risk of surgery, the neurotoxicity of immunosuppression therapy, and the effects of aging and related comorbidities, our data indicate that LT is able to significantly improve patients' cognitive functions in the long term.
Scale Development of Intelligent Home Care Service Quality

Aging has become a worldwide problem. Intelligent home care is the current stage of the more innovative ways of providing for the aged. Objective and impartial evaluation of the quality of care services for the elderly has an important significance to improve the pension system, this paper attempts to build a intelligent home care service quality model. On the basis of the SERVQUAL model, this paper, from the five dimensions of reliability, ease of use, visibility, responsiveness and empathy, the development of intelligent home care service quality scale. The exploratory factor analysis of the scale of the reliability and validity of internal consistency reliability analysis, test results show that the dimensions of the wisdom of home-based care services quality is reasonable, all items through the validity test. Keywords: Intelligent Home Care; Service Quality; Scale Development
Assembly and comparative analysis of complete mitochondrial genome sequence of an economic plant Salix suchowensis

Willow is a widely used dioecious woody plant of Salicaceae family in China. Due to their high biomass yields, willows are promising sources for bioenergy crops. In this study, we assembled the complete mitochondrial (mt) genome sequence of S. suchowensis with the length of 644,437 bp using Roche-454 GS FLX Titanium sequencing technologies. Base composition of the S. suchowensis mt genome is A (27.43%), T (27.59%), C (22.34%), and G (22.64%), which shows a prevalent GC content with that of other angiosperms. This long circular mt genome encodes 58 unique genes (32 protein-coding genes, 23 tRNA genes and 3 rRNA genes), and 9 of the 32 protein-coding genes contain 17 introns. Through the phylogenetic analysis of 35 species based on 23 protein-coding genes, it is supported that Salix as a sister to Populus. With the detailed phylogenetic information and the identification of phylogenetic position, some ribosomal protein genes and succinate dehydrogenase genes are found usually lost during evolution. As a native shrub willow species, this worthwhile research of S. suchowensis mt genome will provide more desirable information for better understanding the genomic breeding and missing pieces of sex determination evolution in the future.
Optic Nerve Head Blood Flow, as Measured by Laser Speckle Flowgraphy, Is Significantly Reduced in Preperimetric Glaucoma

ABSTRACT Purpose: To compare optic nerve head (ONH) blood flow in healthy eyes, eyes with preperimetric glaucoma (PPG), and eyes with mild normal-tension glaucoma (NTG) using laser speckle flowgraphy (LSFG). Methods: In 172 eyes (normal: 44 eyes; PPG: 62 eyes; mild NTG: 66 eyes), LSFG was used to measure mean blur rate in the ONH tissue area (MBRT), an index of capillary blood flow. Multiple regression analysis was performed to determine factors affecting circumpapillary retinal nerve fiber layer thickness (cpRNFLT), mean deviation (MD) and pattern standard deviation (PSD) of the visual field.Results: Despite similar characteristics in age, refractive error and systemic variables among the study groups, MBRT in the normal eyes differed significantly from both the PPG and mild NTG eyes (P = 0.001, P < 0.001, respectively). Multiple regression analysis revealed that MBRT was an independent factor affecting cpRNFLT, MD and PSD (P < 0.001, P = 0.001, P = 0.003, respectively). Conclusion: ONH blood flow was detectibly reduced in eyes with PPG, in close association with structural and visual field damage. This suggests that measuring ONH tissue-area blood flow with LSFG may be a useful way of monitoring glaucoma severity, even in the early stages of glaucoma.