Miracle-dz/UniFAR-FTUs huggingface dataset:
Treatment of condyloma acuminatum with three different interferon-alpha preparations administered parenterally: a double-blind, placebo-controlled trial.

One hundred seventy-eight patients were enrolled in a placebo-controlled trial to evaluate three interferon-alpha preparations administered parenterally for the treatment of condyloma acuminatum. When all interferon groups were combined and compared with placebo, interferon recipients had greater rates of complete, 75%, 50%, and 25% lesion resolution than did placebo recipients (P = .21, P = .14, P = .02, and P = .02, respectively). Rates of lesion resolution were higher among women than among men, and women were more likely than men to respond to interferon. Virologic measurements in paired lesion biopsies did not correlate with interferon treatment or disease outcome. Although interferon toxicity was observed frequently, no participant withdrew from the study because of side effects, and dosage alterations were not required. Parenterally administered interferon-alpha is more effective than placebo in treating condyloma acuminatum, although rates of complete response are low. Different regimens, including combination therapy, should be evaluated for treatment of this common sexually transmitted disease.
Pharmacological activation of KCa3.1/KCa2.3 channels produces endothelial hyperpolarization and lowers blood pressure in conscious dogs

BACKGROUND AND PURPOSE In rodents, the endothelial KCa channels, KCa3.1 and KCa2.3, have been shown to play a crucial role in initiating endothelium‐derived hyperpolarizing factor (EDHF) vasodilator responses. However, it is not known to what extent these channels are involved in blood pressure regulation in large mammals, which would also allow us to address safety issues. We therefore characterized canine endothelial KCa3.1 and KCa2.3 functions and evaluated the effect of the KCa3.1/KCa2.3 activator SKA‐31 on blood pressure and heart rate in dogs.
Evaluation of satisfaction and repurchase intention in online food group-buying, using Taiwan as an example

Purpose – The purposes of this study are: to investigate the relationship of personal background to online group buying's satisfaction and to establish the relationship between consumer's satisfactions and repurchase intention. Design/methodology/approach – This research used a questionnaire to survey and chose consumers with online group buying experience as research subjects. The study used SPSS statistic software to analyze. Findings – The outcomes of this study are: demographic variables have effects on consumer's online food group-buying satisfaction. Consumer's satisfaction has an effect on repurchase intention. Originality/value – This paper investigates the relationship of personal background to online group buying's satisfaction. It establishes the relationship between consumer's satisfaction and repurchase intention.
Importance of the Surveillance Method: National Prevalence Studies on Nosocomial Infections and the Limits of Comparison

Abstract Objective: To demonstrate the limits of comparison of national prevalence rates of nosocomial infections. Design and Setting: Critical analysis of prevalence rates and methods of the Nosocomial Infections in Germany (NIDEP) study and other prevalence surveys with particular attention to the selection of patients, the qualification and training of the investigators, and the methods of identifying nosocomial infections. Results: The lowest prevalence rate was found in Germany (3.5 %), the highest in Belgium (9.3 %). These differences may not be accurate, because variations in methods allow for differing explanations. Conclusions: Because of numerous methodological factors, comparison of infection rates between countries should be avoided. In contrast to other prevalence studies, the methodology of the German-NIDEP study permits registration of only certain infections, which is the main reason for the low rate.
Milk performance of dairy cows supplemented with rapeseed oil, peanut oil and sunflower seed oil

The objective of the study was to investigate the effects of supplementing different plant oils to the basal diet on milk yield and milk composition in mid-lactating dairy cows. Forty Chinese Holstein dairy cows averaging 120 days in milk (DIM) at the start of the experiment (body weight = 580 ± 18.2 kg; milk yield = 33.0 ± 2.00 kg/day) were used in a completely randomized block design. The animals were assigned to four dietary treatments according to DIM and milk yield, and supplemented with no oil (control), 2% rapeseed oil (RSO), 2% peanut oil (PNO) and 2% sunflower seed oil (SFO). Milk yield and milk composition (fat, protein, and lactose) were measured. Dry matter intake was similar in all treatments. The supplementation of plant oil increased milk yield, with the highest milk yield in RSO group. Percentages of milk fat, lactose, solids-not-fat and SCC were not affected by treatments except for an increase in milk protein content in oil supplemented groups. The fatty acid (FA) profile of milk was altered by fat supplementation. Feeding plant oils reduced the proportion of both short-chain (C4:0 to C12:0) and medium-chain (C14:0 to C16:1) fatty acids, and increased the proportion of long-chain (≥ C18:0) fatty acids in milk fat. The inclusion of vegetable oils increased the con centration of cis-9, trans-11 CLA. The cis-9, trans-11 CLA content in milk fat was higher from RSO to PNO and SFO was higher than the control. The TVA concentration was higher in the SFO diet, followed by PNO, RSO, and control diets. The results of this study indicated that linoleic acid was more effective in enhancing contents of TVA and CLA in milk fat than oleic acid. No significant effects of week and treatment by week interaction were found out in this study. Overall, feeding plant oils increased monounsaturated and polyunsaturated fatty acids and decreased saturated fatty acids in milk fat. In conclusion, dietary supplementation of RSO increases milk yield the most, while SFO enhances the cis-9, trans-11 CLA content in milk fat more effectively.
Research on governance pattern of industrial cluster and its evolutionary process

There are structural,process and institutional approaches in investigation of the governance of industrial cluster.A detailed survey on existing literature shows that a well-developed theoretical framework based on institutional approach helps to examine the concept and endogenetic mechanisms of cluster governance.On this basis,the patterns of cluster governance can be classified as three models of self-organizing,center-leading and plural-collaborating.In doing so,we combined deductive and inductive approaches.Further,there is a feedback between the micro governance mechanisms and interactive innovation activities in cluster in the changing environment.It is the dynamic mutual-adaptation between these two parties that induces the evolutionary process of governance pattern of industrial cluster.
Parallel testing techniques for optimizing test program execution and reducing test time

Reducing test time continues to be a priority for test program developers as the complexity of next generation products and devices increases. Test program developers must provide complete test coverage while maintaining or reducing the test time of previous versions as complexity and feature concentration increases. Developers can use different techniques for reducing productspsila test times, such as running tests in parallel which reduces test time without sacrificing test coverage or quality. Other methods include decreasing test coverage by omitting certain lower priority tests or decreasing the quality of tests by only covering a subset of the ranges across which functionality is tested. This paper will discuss techniques for running tests in parallel for different test tasks and cover the factors that affect each type of taskpsilas performance.
Panel Urges Further Study of Biotech Corn

This fall, genetically modified corn that had not been approved for human consumption was found in taco shells in the United States. Last week, the U.S. Environmental Protection Agency (EPA) convened a scientific panel to review evidence on whether this StarLink corn could harm sensitive people by causing allergic reactions. The panel found that the overall probability is "low," but the EPA appears intent on investigating further before allowing the corn in foods, as its manufacturer has requested.
Alcohol-based pressurised metered-dose inhalers for use in asthma: a descriptive study.

BACKGROUND Chlorofluorocarbons (CFCs) have historically served as the propellants of choice in pressurised metered-dose asthma inhalers, but concern has been raised in recent decades regarding their damaging effect on the ozone layer. Among the alternative propellants being considered is alcohol, which can be used as a co-solvent in asthma inhalers. Healthcare professionals need to be aware of alcohol-containing inhalers, since certain populations may have religious and/or cultural concerns regarding the use of such preparations. OBJECTIVES To identify pressurised metered-dose asthma inhalers which contain alcohol-based propellants. METHODS We searched the British National Formulary to identify companies that manufacture asthma treatments and wrote to them to enquire about which of their products contained alcohol and if so in what percentage. These direct contacts were supplemented by searching medical databases and the Internet for additional information. RESULTS We identified 11 manufacturers of asthma inhalers, seven of which produced pressurised metered-dose inhalers; of these, six were willing to disclose the requested information, and information on the seventh product was obtained from an alternative valid source of information. Most CFC preparations contain alcohol, but CFC- and alcohol-free preparations do exist. CONCLUSIONS Clinicians need to be aware that the majority of CFC-free inhalers contain alcohol. Alcohol-free, and CFC- and alcohol-free, preparations are available for the delivery of both rescue and preventative treatment and these should be considered for use in those patients who may have concern about alcohol-based treatments.
Detection system of motor epileptic seizures through motion analysis with 3D accelerometers

A system of epilepsy seizure detection in real life conditions and based on inertial sensors is presented in this paper with a focus on the signal processing to recognize seizure moves. This system is based on several models of signals, one corresponding to general movements, and two others describing seizures moves. The detection algorithm evaluates for a given time window which model fits the best with the observed signals and trigger an alarm if this model is a seizure model. The signal processing algorithm is based on hidden Markov models.
THE 360-DEGREE EMOTIONAL COMPETENCY PROFILER AS A PREDICTOR OF LEADERSHIP ABILITY

Leadership has been defined as the competencies and processes required to enable and empower ordinary employees to do extraordinary things in the face of adversity, it has the added advantage of constantly delivering superior performance to the benefit of individual employees and the organisation, thereby improving returns on investment for shareholders. These behaviours include being skilled in emotional competencies This study focused on the emotional intelligence factors considered characteristic of effective leaders. Forty-eight high potential leaders (HPL) that were selected as part of the companies talent management program were included in the study. Their ratings on the 360-degree Emotional Competency Profiler (ECP) where compared to a group of twenty-four employees that were excluded from this program. Qualitative and quantitative methods where used to explore the relationship between leadership and emotional intelligence. Focus groups were used as qualitative method to determine the relationship between emotional intelligence as measured using the Emotional Competency Profiler (ECP), leadership and the leadership requirements placed on leaders as documented within the talent management program. The results from these discussions indicated a positive relationship between, emotional intelligence, leadership theory and the leadership requirements of the company. Quantitative methods where used to compare the ratings of leaders with nonleaders. The gap identified between current EQ behaviour and the importance of the EQ behaviour were used to indicate the leadership demands placed on the high potential leader and non-leader groups. The outcome of the study indicated the value and application of emotional intelligence (EQ) as component of effective leadership. It is well known that emotionally intelligent leaders have the ability to engage the hearts, minds and imaginations of ordinary people. They inspire people to perform beyond their own expectations. These leaders create a sense of ownership, belonging, security and joint destiny in situations of uncertainty and change. The result is that employees trust these leaders and approach their jobs with greater commitment. The resulting teamwork, mutual support and co-operation create a work environment were employees become creative and innovative. Teams with emotionally intelligent leaders reach a level of synergy that lifts their performance to a level that is more than the sum total of the individual contributions.
Research on the Impact of Technological Capability and Innovation Strategy on Innovation Performance

This paper classifies technological capabilities into absorptive capacity and technical innovation capability,and innovation strategy into exploratory innovation and exploitative innovation.It proposes hypothesis about the correlation between technical capability,innovation strategy and the formation of innovative enterprises from the literature analysis.To verify the hypothesis,it collects data of 257 samples through the questionnaire,and finds that technological capabilities and innovation strategies have a significant impact on innovation performance.The results also show that exploitative innovation has stronger impact on innovation performance than exploratory innovation,but there is no difference between technological innovation capability and absorptive capability on innovation performance.
An Overview of the Mechanisms of HIV-Related Thrombocytopenia

The first thrombocytopenia cases related to the human immunodeficiency virus (HIV) were described even before its isolation in 1983. Subsequently, multiple mechanisms have been proposed to elucidate the etiology of thrombocytopenia. In addition to other types of cytopenia affecting patients with HIV, thrombocytopenia is observed in about 10–50% HIV patients as one of the first clinical signs of infection. Thus, in this review we aim to summarize the mechanisms proposed for thrombocytopenia since the discovery of HIV, and especially the innovations in the field in recent years. Among the different mechanisms suggested for HIV-related thrombocytopenia, there is emphasis on the accelerated destruction of platelets (PLTs) due to the action of immune complexes, and the presence of anti-PLT and anti-HIV antibodies that cross-react with the PLT membrane. There are also secondary causes of thrombocytopenia, such as the effect of drugs and opportunistic diseases associated with HIV.
Equity Volatility Smile and Skew under a CEV Based Structural Leverage Model

The leverage effect is widely considered as the major contributor to volatility skew/smile in the stock option market. This study concentrates on explicit modeling of the corporate leverage. The asset-equity relation is modeled by a perpetual American option, and the asymmetry of the asset return distribution is addressed by introducing a Constant Elasticity of Variance (CEV) asset dynamic. The model retains closed-form representation of firm equity with respect to asset and liability. This provides a convenient simplification to the equity option pricing, so that the model can be calibrated to stock prices and the entire volatility skew/smile. This model successfully demonstrates why low leverage stocks could still have a non-trivial volatility structure, and also shows how the volatility smile, as well as skew, can be accommodated by structural model. Cross-sectional study shows the fitted parameters effectively outlines the financial characteristics of the leveraged firms. The credit quality measure generated from this model is also more powerful in terms of explaining the CDS movements.
Cortical activation during Braille reading is influenced by early visual experience in subjects with severe visual disability: A correlational fMRI study

Functional magnetic resonance imaging was performed on blind adults resting and reading Braille. The strongest activation was found in primary somatic sensory/motor cortex on both cortical hemispheres. Additional foci of activation were situated in the parietal, temporal, and occipital lobes where visual information is processed in sighted persons. The regions were differentiated most in the correlation of their time courses of activation with resting and reading. Differences in magnitude and expanse of activation were substantially less significant. Among the traditionally visual areas, the strength of correlation was greatest in posterior parietal cortex and moderate in occipitotemporal, lateral occipital, and primary visual cortex. It was low in secondary visual cortex as well as in dorsal and ventral inferior temporal cortex and posterior middle temporal cortex. Visual experience increased the strength of correlation in all regions except dorsal inferior temporal and posterior parietal cortex. The greatest statistically significant increase, i.e., ∼30%, was in ventral inferior temporal and posterior middle temporal cortex. In these regions, words are analyzed semantically, which may be facilitated by visual experience. In contrast, visual experience resulted in a slight, insignificant diminution of the strength of correlation in dorsal inferior temporal cortex where language is analyzed phonetically. These findings affirm that posterior temporal regions are engaged in the processing of written language. Moreover, they suggest that this function is modified by early visual experience. Furthermore, visual experience significantly strengthened the correlation of activation and Braille reading in occipital regions traditionally involved in the processing of visual features and object recognition suggesting a role for visual imagery. Hum. Brain Mapping 14:186–195, 2001. © 2001 Wiley‐Liss, Inc.
Jumper's Knee in Volleyball Athletes: Advancements in Diagnosis and Treatment

Jumper's knee, or patellar tendinopathy, affects nearly one half of elite volleyball athletes and causes significant morbidity. The diagnosis and treatment of jumper's knee is evolving with heavier reliance on the use of diagnostic ultrasound with and without color or power Doppler. Research suggests that conservative treatment is very effective using an eccentric exercise regimen and decline squats. Interventional treatments are expanding as well, with positive results seen using extracorporeal shock wave therapy and polidocanol sclerosing injections. Arthroscopic surgical approaches are being developed, some using intra-operative ultrasound guidance. The findings of several recent basic science studies imply that the future may lie in developing a greater understanding of, and then possibly modulating the balance of, the local neuronal, vascular, or biochemical factors associated with symptomatic patellar tendinopathy.
Collaborative Communication in Interfirm Relationships: Moderating Effects of Integration and Control

Governance strategies, such as integration or control, structure and regulate the conduct of parties in exchange relationships; as such, they serve to constrain the latitude of the decision making of channel partners. Similarly, collaborative communication can be used to create an atmosphere of mutual support, thereby creating volitional compliance between partners. The authors develop a model that addresses the interrelationships of governance and communication and examine the effects of collaborative communication on channel outcomes (the dealer's perceptions of commitment to, satisfaction with, and coordination of activities with a focal manufacturer) across various levels of integration and control. Based on survey data collected from a national sample of computer dealers, the findings indicate that when levels of integration or manufacturer control are high, the effect of collaborative communication on outcomes is weaker than when integration or control is low.
Choline Acetyltransferase: Regional Distribution In the Abdominal Ganglion of Aplysla

Using a new microassay, we have determined the properties and the regional distribution of choline acetyltransferase in the abdominal ganglion of Aplysia. Enzyme concentrations in homogenates of groups of cells and in single identified cells indicate that neurons which function as neurosecretory cells, and which do not form chemical synapses with other cells or with peripheral structures, have little or no ability to synthesize acetylcholine; neurons which are involved in visceromotor integrations, and which connect with each other or with the periphery, have a substantial concentration of the enzyme.
Quo Vadis, marketing? Toward a relationship marketing paradigm

The marketing mix and its 4Ps have remained the marketing paradigm for decades. In the article it is argued that the foundation for this paradigm is weak and that it has had negative effects on marketing research and practice. Contemporary research into services marketing and industrial marketing demonstrates that a new approach to marketing is required. This new approach is based on building and management of relationships. A paradigm shift in marketing is under way. The thoughts and actions of marketing academics and practitioners should not be constrained by a paradigm from the 1950s and 1960s.
Benefiting from network position: firm capabilities, structural holes, and performance

While strategy scholars primarily focus on internal firm capabilities and network scholars typically examine network structure, we posit that firms with superior network structures may be better able to exploit their internal capabilities and thus enhance their performance. We examine how innovative capabilities—both those of focal firms and those they access through their networks—influence the performance of Canadian mutual fund companies. We find that a firm's innovative capabilities and its network structure both enhance firm performance, while the innovativeness of its contacts does not do so directly. Innovative firms that also bridge structural holes get a further performance boost, suggesting that firms need to develop network‐enabled capabilities—capabilities accruing to innovative firms that bridge structural holes. Copyright © 2005 John Wiley & Sons, Ltd.