Miracle-dz/UniFAR-FTUs huggingface dataset:
Characterization of Lipid Bilayers and Protein Assemblies Supported on Rough Surfaces by Atomic Force Microscopy

Supported lipid bilayers (SLBs) and two-dimensional protein assemblies formed on solid supports of various roughnesses were characterized by atomic force microscopy (AFM). The presence of SLBs was detected reliably by force measurements and by imaging. Three types of responses could be distinguished depending on the applied loads. These responses are interpreted as due to transient restructuration of the lipid assembly in the region of contact between lipid-covered support and AFM tip, driven by hydrophobic/ hydrophilic interactions. Two-dimensional crystals of streptavidin could be resolved on SLBs formed on silicon wafers, whereas annexin A5, previously shown to crystallize on mica-SLBs, formed a close-packed noncrystalline assembly on lipid bilayers supported by silicon wafers.
Designing for the Urban Night: An Interdisciplinary Course on Lighting, Technology and Urban Design

Lighting design for urban public spaces increasingly requires an integration of strategies from urban design, planning, interactive technologies and lighting design. Few academic programs provide the context for teaching these subjects together. We report on the results of an innovative graduate design workshop taught at the MIT Media Laboratory where we introduced an interdisciplinary group of architects, urban planners, and engineers to the technical, cultural and social issues surrounding the design for urban spaces at night. These contextual details were tied to specific research and design exercises in the field. Ultimately, students selected sites and built full-scale interventions in public space, with results ranging from digital fireflies to analog shadow playgrounds.
Measurement-based evaluation of antenna- and time diversity for mobile satellite systems

Signal diversity is used as a common method to improve the service availability in digital satellite communication and broadcasting systems. This paper focuses on the achievable receive antenna- and time diversity gain for land mobile satellite applications in various environments. A measurement van was equipped with four antennas, mounted at the front, back, left and right side of the rooftop. A high-power satellite broadcasting signal within the S-band was recorded along the east coast of the United States. The diversity gain is calculated from the first-order statistics of the measured high-resolution fading signals.
SIMULATING THE IMPACT ON BUILDINGS OF CHANGING CLIMATE - CREATION AND APPLICATION OF ERSATZ FUTURE WEATHER DATA FILES

Predicted climate change is often reported as the mean seasonal change between climate variables averaged over a given period, while thermal and other energy engineering simulations often require hourly representation of climate variables (elements). This paper describes a method of combining seasonal increments with hourly data representing the present climate. The resulting hourly data are representative of future climate estimates. These future climate estimates have then been used to simulate the effects of future climate change on the energy consumption and plant sizing of buildings. Similar simulations were also carried out to assess the future impacts on the performance of solar water heaters and building integrated photovoltaics.
Towards a reconstruction of macroeconomics using a stock flow consistent (SFC) model

This paper aims to rehabilitate “stock flow consistent” (SFC) macroeconomics as a radical alternative to the neo-classical approach which has dominated the subject during the last thirty years. Commercial banks are reckoned to play a central role in the macroeconomic process because they co-ordinate all the disparate aspirations, expectations and actions of the different sectors and this is one of many ways in which the model deployed here differs, not only from mainstream models, but also from “old fashioned” Keynesian models which have largely become extinct. A comprehensive system of stock and flow accounts, using four sectors and seven financial assets, will be deployed, followed by a narrative description of a theoretical model which can be numerically solved to yield sequences evolving in real time towards steady states. Details of the model’s equations are not disclosed but the paper clearly indicates an alternative methodology, while the simulations lend plausibility to some distinctive conclusions.
A Clinical and In Vitro Study of the Distal Hereditary Motor Neuropathies

The hereditary motor neuropathies (HMN) encompass diseases of motor axons and neurons and range from the progressive, length dependent distal hereditary motor neuropathies (dHMN) to the developmental, non-progressive dominant congenital spinal muscular atrophies (DCSMA). In this Thesis I have investigated the pathomechanisms of HMN and undertaken a natural history study of patients with dHMN. In Chapter 2 I investigated the pathomechanism of dHMN due to homozygous mutations in the heat shock protein HSJ1, using primary motor neurons (MNs) from HSJ1 knockout mice. Using live cell confocal imaging I examined mitochondrial axonal transport and ER calcium levels, but found no evidence of axonal transport deficits or ER stress. In Chapter 3 I examined the pathomechanism of dHMN due to a novel mutation in FBXO38. FBXO38 modulates the transcriptional activity of KLF7; a transcription factor with a role in neuronal development and repair. I therefore examined neurite outgrowth in lentivirus-infected primary MNs and demonstrated a reduction in neurite outgrowth in mutant FBXO38 infected MNs. In Chapter 4, I identified a mutation in a new disease gene, BICD2, in a family with a form of DCSMA termed lower extremity dominant SMA. BICD2 is a dynein adaptor protein and using immunoprecipitation I found that two disease mutations in BICD2 increase dynein binding affinity. In Chapter 5, I performed a genetic study of the HMNs and showed that mutations in HSPB1 are the most common cause of dHMN. I also evaluated plasma neurofilament heavy chain (NFH) as a biomarker of disease activity in the inherited neuropathies but was unable to detect a difference between patients and healthy volunteers. This would suggest that plasma NFH levels are not a suitable biomarker of disease activity in the inherited neuropathies.
Evaluatie van part-of-speech taggers voor het corpus gesproken nederlands

Een van de annotatieniveaus van het Corpus Gesproken Nederlands CGN gaat bestaan uit gedisambigueerde morfo syntactische woordcategorie en tags Om het taggen van de grote hoeveelheid materiaal in het CGN mogelijk te maken moet gebruik worden gemaakt van een automatische tagger De taak van deze tagger bestaat uit het leveren van lexicale informatie de mogelijke categorie en van een woord en het waar nodig disambigueren op basis van de context Aangezien het doel van het project de productie van een corpus is is de belangrijkste eis aan de tagger dat deze het annotatie en correctieproces zo accuraat en e cient mogelijk maakt De tagger moet zo weinig mogelijk fouten maken en het moet de menselijke annotatoren eenvoudig gemaakt worden de gemaakte fouten te corrigeren Voor een uitgebreidere beschrijving van de taak en de randvoorwaarden verwijs ik naar de meest recente versie van het stuk CGN tagset Van Eynde dd Er is op het moment een heel scala aan tagger technologie beschikbaar Het is op dit punt belangrijk een onderscheid te maken tussen de tagger dwz een stuk software dat taalkennis bevat en ruwe tekst van tags kan voorzien en een tagger generator dwz een stuk software dat getraind wordt op een getagd corpus en een tagger oplevert Er bestaan een aantal kant en klare taggers voor het Nederlands nader beschreven in Sectie De meeste van deze taggers zijn statistisch of lerend van aard en zijn dus gemaakt door een tagger generator die in de meeste gevallen ook beschikbaar is We noemen deze dus ook trainbare taggers Daarnaast zijn er tagger generatoren die nog nooit op het Nederlands zijn toegepast maar die ook in aanmerking komen De meeste state of the art trainbare taggers halen een accuraatheid van tussen de en procent afhankelijk van tagset en hoeveelheid trainingsmateriaal meestal gemeten over alle teksttokens dus inclusief niet ambigue woorden en punctuatie Deze percentages
The Impact of Patient-Centered Narrative Interviewing on the Perceptions of Primary Care Clinicians: a Pilot Evaluation

4 SECTION I: CLINICAL PROBLEM 6 PROBLEMS WITH A CLINICIAN-CENTERED APPROACH 7 PROBLEMS WITH A PATIENT-CENTERED APPROACH 7 IDENTIFYING THE ESSENTIAL ELEMENTS OF PATIENT-CENTERED INTERVIEWING 8 MAKING THE PERSONAL TRANSFORMATION REQUIRED TO PRACTICE 9 PATIENT-CENTERED INTERVIEWING SECTION II: CLINICAL SOLUTION 14 COMPONENTS OF EVIDENCE-BASED PATIENT-CENTERED INTERVIEWING 15 SKILLS USED SIMULTANEOUSLY 15 RAPPORT BUILDING AND THE RELATIONSHIP MAINTENANCE 15 MINDFUL PRACTICE 15 TOPIC TRACKING 16 ACKNOWLEDGING SOCIAL OR EMOTIONAL CLUES WITH EMPATHY 16 SKILLS USED SEQUENTIALLY 17 UP-FRONT, COLLABORATIVE AGENDA SETTING 17 EXPLORING THE PATIENT’S PERSPECTIVE 18 CO-CREATING A PLAN 18 PATIENT-CENTERED INTERVIEWING IN A NARRATIVE MODE 19 HISTORY AND BASIC CONCEPTS 19 APPLICATION IN PATIENT-CENTERED INTERVIEWING SKILLS 22 RAPPORT BUILDING AND THE RELATIONSHIP MAINTENANCE 22 MINDFUL PRACTICE 23 TOPIC TRACKING 23 ACKNOWLEDGING SOCIAL OR EMOTIONAL CLUES WITH EMPATHY 24 UP-FRONT, COLLABORATIVE AGENDA SETTING 24 EXPLORING THE PATIENT’S PERSPECTIVE 25 CO-CREATING A PLAN 25 SECTION III: PROJECT IMPLEMENTATION 26 PURPOSE 27 RATIONALE AND ASSUMPTIONS 27 OVERALL DESIGN AND OBJECTIVES 27 OUTCOMES EVALUATED 28 SETTING 30 TRAINING APPROACH AND METHOD 31 INTERVENTION AND DATA COLLECTION 32 SECTION IV: PROJECT EVALUATION 35 RESULTS 36 PARTICIPANT CHARACTERISTICS 36 OUTCOMES 38 PCC PERCEPTIONS OF PATIENT’S CONDITION, DIAGNOSIS AND TREATMENT PLANS 38 VALUE OF INFORMATION PROVIDED TO PCC 40 PCC FRUSTRATION 40 DIFFERENCES BETWEEN CLINICIAN AND INTERVIEWER ASSESSMENTS OF PATIENT PROBLEMS 40 ANALYSIS 41 PARTICIPANTS AND SITES 41 OUTCOMES 42 CLINICIAN PERCEPTIONS 3 PCC PERCEPTIONS OF PATIENT’S CONDITION, DIAGNOSIS AND TREATMENT PLANS 42 VALUE OF INFORMATION PROVIDED TO PCC 43 PCC FRUSTRATION 44 DIFFERENCES BETWEEN CLINICIAN AND INTERVIEWER ASSESSMENTS OF PATIENT 44 PROBLEMS 44 DISCUSSION 44 SECTION V: NEXT STEPS 47 SECTION VI: IMPLICATIONS FOR ADVANCED PRACTICE NURSING 54 CONCURRENCE WITH NURSING THEORY 55 CONCURRENCE WITH DNP COMPETENCIES 57
High levels of gene flow and low population genetic structure related to high dispersal potential of a tropical marine angiosperm

Marine ecosystems are traditionally considered to be highly connected, caused by long- distance movements of propagules in an open fluid medium. But this principle is not universal, and populations of many marine organisms have restricted gene-flow, including ones with drifting propagules. Direct tracking of marine free-floating propagules over large distances is virtually impossible, but long-distance dispersal (LDD) can be deduced from their drifting time and transport rates. Alternatively, LDD can be estimated as genetic exchange with the use of allelic frequency data obtained with genetic markers. The present study compares both approaches of LDD estimation for the tropical seagrass Thalassia testudinum. Fruit dispersal potential was measured in Puerto Morelos reef lagoon, Mexico. Between 10 and 15% of the fruits floated to the surface (floating potential <1 to 10 d), with a derived potential dispersal of <1 to 360 km. The remainder of the fruits dehisced in situ followed by limited seed dispersal (<1 to 10 m). Genetic diversity was characterized using 6 microsatellite loci for 16 populations distributed along a 1350 km long stretch of the Mexican coast, revealing a total of 58 alleles. AMOVA showed that only 9.75% of the total variation was accounted for by genetic differences between the populations. Isolation by distance was significant, and revealed a panmictic area of 350 km. The results of both approaches of LDD estimation coincided well and the maximum displacement of the fruits of this marine angiosperm exceeded, by 1 to 2 orders of magnitude, the reported seed dispersal by terrestrial seed plants.
Challenges in Treating Pediatric Asthma in Developing Countries

Asthma is the most common chronic disease in children in many lowand middle-income countries. In these settings, the burden of childhood asthma is increasing and is associated with severe disease. There are a number of challenges to providing optimal management of childhood asthma in such settings. These include under-diagnosis of childhood asthma, access to care, ability of healthcare workers to manage asthma, availability and affordability of inhaled therapy, environmental control of potential triggers, education of healthcare providers and of the public, and cultural or language issues. International and national guidelines for childhood asthma have been produced, but implementation remains a real challenge. Access to and affordability of essential inhaled asthma drugs, especially low-dose inhaled corticosteroids and short-acting bronchodilators, aremajor challenges to effective asthma control in many countries. A low-cost spacermade from a plastic bottle is effective for use with ametered-dose inhaler, but use must be included in asthma educational initiatives. Educational programs for healthcare personnel and for the public that are culturally and language appropriate are needed for effective implementation of asthma guidelines. Socioeconomic and structural barriers to care within health services remain obstacles to achieving optimal treatment of asthma for many children.
Ovarian Cancer Incidence: Current and Comprehensive Statistics

Ovarian cancer is a commonly diagnosed and particularly deadly gynecologic malignancy worldwide. It ranks among the top ten diagnosed cancers and top five deadliest cancers in most countries (Ferlay et al., 2010). Several cancer incidence data sources have been used to measure ovarian cancer burden across the world; however, the statistics presented are often not population-based, which can lead to misrepresentation of the burden due to incomplete or inaccurate data. An accurate assessment of ovarian cancer burden is essential as incidence data are used for many purposes including to generate hypotheses regarding etiology, allocate resources and funding toward new treatment discovery and clinical trials, and determine which populations of women may benefit from more education or greater surveillance for the disease. The purpose of this chapter is to present global comprehensive ovarian cancer incidence data. Data collected are from several resources, and every effort is made to present only high-quality data from population-based data sources. Because of changing age structures of populations and differences in data quality and coverage of various data sources over time, only the most recent data are presented. This will aid in preventing misinterpretation of temporal trends.
Geometric parameters of the apical meristem and the quality of phyllotactic patterns in Magnolia flowers

The ratio of primordium size to the meristem size ( P/M ratio) is regarded by some geometrical models of phyllotaxis as the parameter, which determines the quality of spiral and whorled patterns of lateral organ arrangement. This assumption was tested on floral meristems in four genets representing four Magnolia taxa: M. × salicifolia , M. stellata , M. denudata and M. acuminata . In successive zones of Magnolia flower, lateral organs are initiated in specific phyllotactic patterns and at specific values of the meristem and primordia sizes. The elements of perianth, usually positioned in three trimerous whorls, are initiated as large primordia on relatively small meristem. The switch in the identity of primordia, from tepals to stamens is accompanied by an abrupt increase in the size of the meristem and decrease in the primordia size. Small values of P/M ratio and frequent occurrence of qualitative transformations of phyllotaxis contribute to the exceptionally rich spectrum of spiral patterns in androecium zone. New spiral patterns emerge when bigger primordia of carpels are initiated on the meristem, which at the same time starts diminishing in size either abruptly ( M. × salicifolia , M. stellata , M. acuminata ) or slowly ( M. denudata ). Spiral patterns identified in gynoecia have lower numbers of parastichies than the patterns of androecia and occur in frequencies specific for the genet. Although noted ranges of the meristem and primordia sizes, justify the occurrence of phyllotactic patterns observed in successive zones of Magnolia flower, they do not explain genet-specific frequencies of the patterns observed in gynoecium zone. The lack of straightforward relationship between frequency of the patterns and P/M ratio in gynoecium suggests that more complex geometrical factors or factors of non-geometrical nature are engaged in determination of Magnolia floral phyllotaxis.
TEACHING AND LEARNING THROUGH CHAT: A TAXONOMY OF EDUCATIONAL CHAT FOR EFL/ESL

Chat are synchronic communicative spaces which are incorporated into online activities, especially in EFL/ESL courses, due to the possibilities to intera ct with native and non-native speakers of the L2 th ey offer participants. Teachers interested in using ch at for educational purposes should know the characteristics of different chat tasks according to the objective, role of moderator, and structure of the interaction to be generated, in order to plan their activities accordingly. This paper introduces a taxonomy for educational chat which was designed ba sed on the author’s experience using chat with language learners and in-service teachers.
Testüberdeckung als Maß in Quamoco

Um wettbewerbsfahige Softwareprodukte entwickeln und sich von anderen Unternehmen abgrenzen zu konnen, werden die Anforderungen an die Softwarequalitat immer hoher. Eine Moglichkeit diese greifbar und bewertbar zu machen, bieten die Qualitatsmodelle und die zur Verfugung gestellten Werkzeuge von Quamoco. Ein Qualitatsmas von Software ist deren Testuberdeckung, welche bis zum Zeitpunkt der Erstellung dieser Arbeit noch nicht von Quamoco berucksichtigt wird. Ziel dieser Arbeit ist es daher, die Testuberdeckung als Mas in Quamoco zu integrieren. In order to develop competitive software products and to make yourself unique amongst other companies, the need for high quality software rises. One approach to make the quality of software more tangible and assessable is the usage of the Quamoco quality model and its tool chain. One metric of software quality is test coverage. This is not yet covered by Quamoco. Hence, this work aims to integrate test coverage into Quamoco.
Cancer care for the whole patient : meeting psychosocial health needs

Cancer care today often provides state-of-the-science biomedical treatment, but fails to address the psychological and social (psychosocial) problems associated with the illness. This failure can compromise the effectiveness of health care and thereby adversely affect the health of cancer patients. Psychological and social problems created or exacerbated by cancer--including depression and other emotional problems; lack of information or skills needed to manage the illness; lack of transportation or other resources; and disruptions in work, school, and family life--cause additional suffering, weaken adherence to prescribed treatments, and threaten patients' return to health. Today, it is not possible to deliver high-quality cancer care without using existing approaches, tools, and resources to address patients' psychosocial health needs. All patients with cancer and their families should expect and receive cancer care that ensures the provision of appropriate psychosocial health services. Cancer Care for the Whole Patient recommends actions that oncology providers, health policy makers, educators, health insurers, health planners, researchers and research sponsors, and consumer advocates should undertake to ensure that this standard is met.
Impact of oxide substrate on electrical and optical properties of carbon nanotube devices

We have studied suspended nanotube devices to investigate directly the impact of oxide substrate on the properties of nanotubes. The 1/f noise amplitude is reduced by about one order of magnitude when the nanotube is suspended, suggesting that the 1/f noise is dominated by the trapped charges in the oxide. We have also utilized the enhanced Raman signal intensity in suspended nanotubes to correlate electrical transport properties with Raman spectroscopy on the same individual nanotube, yielding close agreement in the tube diameter determined from both types of experiments.
Hyperglycaemia in Hyperthyroidism Predictive Factors

Glucose abnormalities are frequent in hyperthyroidism; the aim of our study is to determine the predisposing factors of glucose disturbances in hyperthyroidism. Subjects and methods : it is a retro and prospective study including 376 hyperthyroid subjects. Patients having fasting glycaemia < 1 g/L and/or glycaemia after 75 gr-Oral Glucose Tolerance Test (OGTT) < 1.40 g/L were compared to patients having fasting glycaemia ≥ 1 g/L and/or glycaemia after OGTT ≥ 1.40 g/L. Results : 44% had glucose abnormalities (12% diabetes and 32% prediabetes). Hyperglycemic patients were older, were more frequently hypertensive and have more familial background of diabetes than normoglycemic patients. Conclusion : Ageing, underlying hypertension and familial diabetes are risk factors for glucose abnormalities in hyperthyroid subjects whereas the severity of hyperthyroidism is not, which suggest that hyperthyroidism may worsen glucose metabolism in patients at risk of type 2 diabetes.
Evaluation of Normal Ultrasonographic Findings of Kidney in Raiini Goat

Objective- to assess the normal ultrasonographic findings of kidney in the Raiini goat. Design- Experimental study. Animals- 10 female Raiini goats. Procedures- . Necropsy was carried out and Kidneys were measured in length, width, and diameter after fixation in formalin. Ultrasonography was carried out by longitudinal and transversal planes to evaluate all renal structures. Echogenicity and size of cortex, medulla, and renal sinuses were evaluated. Results- In longitudinal and transverse scans, cortex, medulla and renal sinuses were seen. Renal pyramids could not be counted in ultrasonography. Conclusion and Clinical Relevance- Evaluation of shape, size and condition of renal tissue is possible by ultrasonography and this study
The limits of leverage

When trading incurs proportional costs, leverage can scale an asset's return only up to a maximum multiple, which is sensitive to its volatility and liquidity. In a model with one safe and one risky asset, with constant investment opportunities and proportional costs, we find strategies that maximize long‐term returns given average volatility. As leverage increases, rising rebalancing costs imply declining Sharpe ratios. Beyond a critical level, even returns decline. Holding the Sharpe ratio constant, higher asset volatility leads to superior returns through lower costs.
Ut: abr feedback control with tracking

We propose an explicit-rate ABR feedback control scheme, UT, that appears to satisfy the criteria of the ATM Forum. The distinct feature of UT is that it achieves max-min fairness by tracking an eeective number of sources; speciic constraint information is not required. As a result, its implementation is much simpler than that of other fair control schemes; indeed, its complexity is similar to that of unfair explicit-rate controls. In the thorough simulation study, UT demonstrates its ability to scale with speed, distance, number of users (both persistent and bursty), and number of nodes while remaining robust, eecient, and fair under stressing conditions with MPEG background traac and multiple propagation delay loops.