Miracle-dz/UniFAR-FTUs huggingface dataset:
Breathomics can discriminate between anti IgE-treated and non-treated severe asthma adults

Rationale: Omalizumab, an anti-IgE monoclonal antibody, is indicated in adults with severe persistent allergic asthma. Exhaled molecular markers can provide phenotypic information in asthma. Objectives: Determine whether adults with severe asthma on omalizumab (anti-IgE + ) have a different breathprint compared with those who were not on anti-IgE therapy (anti-IgE - ) as assessed by eNoses and gas chromatography/mass spectrometry (GC/MS) (breathomics). Methods: This was a cross-sectional analysis of the U-BIOPRED adult cohort. Severe asthma was defined by IMI-criteria [Bel, Thorax 2011]. Anti-IgE + patients were on a regular treatment with s.c. omalizumab (150-375 mg) every 2-4 weeks. Exhaled volatile compounds trapped on adsorption tubes were analysed by a centralized eNose platform (Owlstone Lonestar, two Cyranose 320, Comon Invent, Tor Vergata TEN), including a total of 190 sensors, and GC/MS. Recursive feature elimination (http://topepo.github.io/caret/rfe.html) was used for feature selection and random forests, more robust to overfitting, for classification. Results: 9 anti-IgE + (females/males 2/7, age 52.6±16.3 years, mean±SD, 1/2/6 current/ex/nonsmokers, pre-bronchodilator FEV 1 70.6±21.1% predicted value) and 30 anti-IgE - patients (18/12 females/males, age 53.2±14.2 years, 0/16/14 current/ex/nonsmokers, pre-bronchodilator FEV 1 59.6±30.7% predicted value) were studied. Accuracy of classification is shown in Table 1. Conclusions: Preliminary results suggest that breathomics can distinguish between anti-IgE + and anti-IgE - severe asthma patients.
Analysis of the Structure and Function of Phono-semantic Compounds Based on Complex Networks

Complex network has been used in phonosemantic compounds in this paper, especially the degree correlation, hierarchical structure, diversity of the function of nodes and their relationships has been studied. We found that high degree nodes tend to be connected to low degree nodes, displaying a disassortative mixing property in the whole; some nodes can act both as phonetic radical and semantic radical, leading to a more complicated structure; and the hierarchical structure makes the disassortative mixing property more obvious. This paper reveals that phonosemantic compounds are optimal combination of phonetic radicals with semantic radicals, and they bear the merits of easy remembering, easy spreading and easy understanding. The phono-semantic compounds follow the principle of least effort [1] and characteristics of human cognitive mechanism.
DETERMINING THE CONCENTRATION OF HEAVY METALS IN THE SOILS NEAR SLAG LANDFILLS

The paper presents the study of crops in rural areas along the Siret River basin near the industrial area of Galati, affected by heavy metal pollution The city of Galaţi is situated in the geographic center of the largest hydrographic basin in Europe being in the same time, together with Brăila city one of the most important industrial area in Romania. The present research in are on multicriterial monitoring points complex with prognosis using Kriging method. Interpolation methods estimate the values in unsampled locations. The mapping and spatial analysis often requires converting the field measurements into continuous space. Articolul prezintă studiul culturilor în zonele rurale de-a lungul bazinului râului Siret aproape de zona industrială a oraşului Galaţi, afectate de poluarea cu metale grele. Orasul Galaţi este situat în centrul geografic al celui mai mare bazin hidrografic din Europa, fiind în acelaşi timp, împreună cu oraşul Brăila unul dintre cele mai importante zone industriale din România. Prezenta cercetare se bazează pe punctele de monitorizare complex multicriterial cu prognoza cu ajutorul metodei Kriging. Metode de interpolare estimează valorile în locaţiile dintre punctele de monitorizare. Cartografia şi analiza spaţială necesită adesea convertirea domeniul măsurătorile în spaţiul continuu.
Bengali Information Retrieval System(BIRS)

Information Retrieval System is an effective process that helps a user to trace relevant information by Natural Language Processing (NLP). In this research paper, we have presented present an algorithmic Information Retrieval System(BIRS) based on information and the system is significant mathematically and statistically. This paper is demonstrated by two algorithms for finding out the lemmatization of Bengali words such as Trie and Dictionary Based Search by Removing Affix (DBSRA) as well as compared with Edit Distance for the exact lemmatization. We have presented the Bengali Anaphora resolution system using the Hobbs’ algorithm to get the correct expression of information. As the actions of questions answering algorithms, the TF-IDF and Cosine Similarity are developed to find out the accurate answer from the documents. In this study, we have introduced a Bengali Language Toolkit (BLTK) and Bengali Language Expression (BRE) that make the easiest implication of our task. We have also developed Bengali root word’s corpus, synonym word’s corpus, stop word’s corpus and gathered 672 articles from the popular Bengali newspapers ‘The Daily Prothom Alo’ which is our inserted information. For testing this system, we have created 19335 questions from the introduced information and got 97.22% accurate answer.
A Factorization Approach to C Stabilization of Nonlinear Triangular Systems

We expand the class of systems to which backstepping is applicable, by allowing states that are used as virtual controls to appear in non-invertible maps. Representing these maps as products of C bijective maps and sign definite C 0 gains, we develop a recursive design which is robust to multiplicative uncertainties. When the linearization of the system is controllable, our design achieves global asymptotic stability, otherwise it guarantees global practical stability. The designed feedback system possesses desirable inverse optimality properties.
Turbulence over the Sill of Saanich Inlet , BC , Canada

Saanich Inlet is a physically quiet fjord-estuary, with anoxic deep waters and restricted circulation with the adjacent basins. Despite the limiting conditions, the inlet presents high levels of primary production. Previous works have tried to describe how this primary production is sustained, but no conclusions were made. Vertical mixing could be the mechanism resupplying nutrients from the deep, nutrient-rich waters into the euphotic zone, thus sustaining primary production. We hypothesize that tidal action at the mouth of Saanich Inlet has enough energy to vertically mix the water column. Using a turbulence profiler (VMP-250) we collected microstructure temperature, conductivity and shear data in the water column. The shear data was used to calculate dissipation rates. Our observations show that there is significant turbulence in the inlet, supporting our hypothesis.
Classifi ' cation Using Shorter Roots

Stemming is one of commonly used pre-processing steps in document categorization. Especially when fast and accurate classification of a lot of documents is needed, it is important to have as small number of and as small length roots as possible. This would not only reduce the time it takes to train and test classifiers but also would reduce the storage requirements for each document. In this study, we analyze the performance of classifiers when the longest or shortest roots found by a stemmer are used. We also analyze the effect of using only the consonants in the roots. We use two document data sets, obtained from Milliyet newspaper and Wikipedia to analyze classification accuracy of classifiers when roots obtained under these four conditions are used. We also analyze the classification accuracy when only the first 4, 3 or 2 letters or consonants are used from the roots. Using smaller roots results in smaller number of TF-IDF vectors. Especially for small sized TF-IDF vectors, using only consonants in the roots gives better performance than using all letters in the roots.
Exaggerated Cartoon Style Motion in Hotel Transylvania

The fundamental principles of animation were developed at the Disney studio in the 1930s and when applied to animation result in a recognisable “Disney” style of motion. By adhering to these fundamental principles of animation, Animators have been able to successfully extend the Disney style of motion to the 3D CG medium. This paper goes beyond Disney style motion and examines the adaptation of techniques typically seen in more extreme cartoon-style motion and “pushed posing”, exemplified by early Warner Brothers animated short films. This is achieved via an analysis of Hotel Transylvania by Sony Pictures Animation, which features a stylised form of animation adapted from the extended principles of extreme cartoon-style motion to the 3D medium.
Combining recipes, impressions and aroma measurements

1. Chemometrics and Analytical Technology, Department of Food Science, University of Copenhagen, Denmark, 2. Department of Chemical Engineering and Biotechnology, Université de Sherbrooke, Quebec, Canada, 3. Nordic Food Lab, Design and Consumer Behaviour, Department of Food Science, University of Copenhagen, Denmark 4. Edinburgh Food Studio, Edinburgh, Scotland, United Kingdom 5. Nutritional Sciences and Toxicology, University of California Berkeley, USA 6. Copenhagen NV, Denmark
Persistency semantics of the Intel-x86 architecture

Emerging non-volatile memory (NVM) technologies promise the durability of disks with the performance of RAM. To describe the persistency guarantees of NVM, several memory persistency models have been proposed in the literature. However, the persistency semantics of the ubiquitous x86 architecture remains unexplored to date. To close this gap, we develop the Px86 (‘persistent x86’) model, formalising the persistency semantics of Intel-x86 for the first time. We formulate Px86 both operationally and declaratively, and prove that the two characterisations are equivalent. To demonstrate the application of Px86, we develop two persistent libraries over Px86: a persistent transactional library, and a persistent variant of the Michael–Scott queue. Finally, we encode our declarative Px86 model in Alloy and use it to generate persistency litmus tests automatically.
Por cine Liver

A nar row-band ul tra sonic shear-wave im ag ing tech nique for es ti mat ing phase speed was ap plied to fresh and ther mally dam aged por cine liver in vi tro. Two con sti tu tive mod els were ap plied to the mea sure ments to rep re sent rhe o log i cal be hav ior of the tis sue and es ti mate the com plex shear modulus at fre quen cies be tween 50 and 300 Hz. Our re sults were com pared to sim i lar val ues from the lit er a ture to as sess how well mod els rep re sent liver mea sure ments over a range of shear-wave fre quen cies, ex per i men tal con di tions and mam ma lian spe cies. We found re mark able con sis tency in some pa ram e ters but not in oth ers, sug gest ing that the Kel vin-Voigt model com monly ap plied in elas tic ity-im ag ing sit u a tions is rep re sen ta tive of tis sue dis per sion but the de scrip tion it of fers is in com plete. Data are con sis tent with the the ory that viscoelastic con trast is more likely due to changes in pro tein and other biomolecular-scale struc tures than from tis sue anat omy larger than a cell. Dis per sion mea sure ments at fre quen cies be tween 0.5-1000 kHz are needed to more com pletely eval u ate mod els for the viscoelastic be hav ior liver.
Functional MRI of Mirror Movements in Congenital Hemiparesis

Martin Staudt1, Wolfgang Grodd2, Gerhard Niemann1, Christian Gerloff3, Inge Kraegeloh-Mann1 1Dept. Pediatric Neurology, University Children's Hospital, Hoppe-Seyler-Str. 1, Tuebingen, Germany; 2Section Experimental MR of the CNS, Dept. Neuroradiology, University Radiology Clinic, Hoppe-Seyler-Str. 3, Tuebingen, Germany; 3Cortical Physiology Research Group, Dept. Neurology, Tuebingen University, Hoppe-Seyler-Str. 3, Tuebingen, Germany;
Protection against Acute Pingyangmycin-induced Lung Injury: A novel Role for Low-dose Radiation

Endotracheal challenge in mice with pingyangmycin (bleomycin A5, PYM) is a well-established model for acute lung injury resulting in pulmonary fibrosis. Immune hormesis induced by low-dose radiation has been proven effective in lymphocyte, macrophage, and natural killer cells. This study examines the effects of low-dose radiation on pingyangmycin-induced pulmonary fibrosis and the relationship between cytokine levels and pulmonary fibrosis induced by pingyangmycin. Kunming strain male mice were exposed to whole-body low-dose radiation (total dosage: 75 mGy). After 6 h, the mice were subjected to inhalation of PYM atomization at a concentration of 2 mg/mL. The effect of low-dose radiation on pulmonary damage was analyzed by observing HE slices under a light microscope and analyzing the cytokine levels (IL-6) in the bronchoalveolar lavage fluid using ELISA. TNF-α and TGF-β levels were detected by immunohistochemistry. During the early stage of pingyangmycin-induced lung injury, the experimental group had lower grade of alveolitis compared with the control group (P < 0.05). In addition, the IL-6 level in the experimental group was lower than that of the control group and was close to that of the blank group. The experimental group also had lower TGF-β and TNF-α expression compared with the control group (P < 0.05). Low-dose radiation (75 mGy) can reduce alveolitis grade, IL-6 secretion, and TGF-β and TNF-α expression. (Hongsheng Yu, Zimin Liu, Xiaoyun Yu, Aiqin Song, Ning Liu, Hao Wang. Protection against Acute Pingyangmycin-induced Lung Injury: A novel Role for Low-dose Radiation. Life Sci J 2013; 10(3): 1204-1209). (ISSN: 1097-8135). http://www.lifesciencesite. com 178
EfECTOS DE UN PROTOCOLO APLICADO POR ENfERMERAS EN EL CONTROL METABÓLICO A PERSONAS CON DIABETES TIPO 2 EFFECTS OF A PROTOCOL FOR NURSES IN APPLIED METABOLIC CONTROL IN PEOPLE WITh TyPE 2 DIABETES

RESUMEN El proposito de este estudio cuasi experimental fue evaluar los efectos del control metabolico antes y despues de la intervencion educativa para pacientes con diabetes tipo 2, en el Estado de Hidalgo, Mexico. Participaron 82 pacientes, se formaron dos grupos: grupo intervencion, recibio consultas de enfermeria conjuntamente con el equipo multidisciplinario, y grupo control fue con una intervencion tradicional. En ambos grupo se determino peso, talla, niveles sericos, glucosa sanguinea en ayuno, colesterol HDL, LDL, hemoglobina glucosilada, du-rante seis meses. El analisis de datos se efectuo con la prueba de significacion t student p=0.05. Los dos grupos participantes con predominio mujeres, mayores de 50 anos, casadas, empleadas y jubiladas, y con un promedio de escolaridad de 5.9± 2.8 anos. Despues de la intervencion, los promedios de HbA1c disminuyeron en forma significativa en el grupo de intervencion; las concentraciones de HbA1c fueron mayores en el grupo control (5.65±0.99
CORRELAÇÕES ENTRE MOBILIDADE E INDEPENDÊNCIA FUNCIONAL EM IDOSOS INSTITUCIONALIZADOS E NÃO-INSTITUCIONALIZADOS

Alteracoes na independencia funcional e na mobilidade sao problemas que afetam parte importante dos idosos, gerando limitacoes na execucao das atividades de vida diaria e reduzindo sua qualidade de vida. Este estudo teve como objetivo comparar e correlacionar a mobilidade e a independencia funcional de idosos institucionalizados e nao-institucionalizados. Participaram 35 idosos com idade media de 70 (+7,2) anos, sendo 18 residentes na comunidade (88% do sexo feminino e 11,9% do masculino) e 17 residentes em instituicao (82,4% do sexo masculino e 17,6% do feminino). Foram utilizados o Teste Timed Up and Go (TUG) para a avaliacao da mobilidade e a Medida de Independencia Funcional (MIF) para avaliar a capacidade funcional. A analise estatistica de variância foi feita por meio dos testes Mann-Whitney, Wilcoxson e T-Student e foi utilizada a Correlacao de Pearson para correlacionar as variaveis em estudo. Foram observadas diferencas significativas entre os grupos nos itens autocuidado, transferencias e locomocao, e tambem no tempo de realizacao do TUG. Foi encontrada correlacao diretamente proporcional entre a MIF motora e a MIF cognitiva e correlacao relativa inversamente proporcional entre a MIF Motora e o TUG (p=0,003). A independencia funcional dos idosos institucionalizados participantes e menor que dos idosos naoinstitucionalizados e e possivel inferir que alteracoes da cognicao podem estar relacionadas as alteracoes na execucao das atividades que determinam a capacidade funcional.
Quality of life in erectile dysfunction patients and their partners responding to tadalafil versus sildenafil citrate

Background Erectile dysfunction (ED) is considered the most common sexual problem in men, with a direct impact on the life of the patient and their partners. Quality of life (QOL) has become a useful variable to assess the overall impact of diseases and medical treatments from the patient’s point of view. Aim The aim of this study was to estimate the QOL in ED patients responding to tadalafil versus sildenafil citrate as well as that of their partners and also to find out the type of treatment associated with the best QOL among these patients. Methods The present study was carried out over a period of 2 months and involved 60 diagnosed ED patients and their partners who were divided into two groups. Group A comprised 30 male patients who responded to tadalafil (20 mg) on demand therapy as well as their partners. Group B comprised 30 male patients who responded to sildenafil citrate (50 mg) on demand therapy as well as their partners. All patients included in the study were subjected to a thorough medical history taking, physical and genital examination, and QOL assessment using the WHO QOL BREF questionnaire before administration of tadalafil or sildenafil as a treatment for their condition; they were then reassessed after 2 months. Results The present study showed that ED has a negative impact on all domains of QOL. Conclusions Treatment with tadalafil or sildenafil improves QOL for both the patients and their partners in different domains of QOL.
Serum folic acid is reduced in patients with Alzheimer's disease Redução dos níveis séricos de ácido fólico em pacientes com a doença de Alzheimer

Background: Complex B vitamin deficiency has been associated to cognitive impairment and dementing disorders in the elderly. Objective: This work aims to assess whether patients with Alzheimer’s disease (AD) and mild cognitive impairment (MCI) have lower levels of folic acid and cobalamin (vitamin B12) compared to age and gender-matched controls. Methods: One hundred and forty six elderly subjects (40 AD, 56 MCI and 49 healthy older adults) were recruited for this study. Serum folic acid and vitamin B12 levels were measured by electrochemoluminescence. Results: Compared to MCI and healthy controls a statistically significant reduction in serum concentrations of folic acid in AD patients was found (p = 0.02). This result remained statistically significant after controlling for socio-demographic and cognitive performance variables (p = 0.01). No significant differences were found in serum concentrations of vitamin B 12 in patients with AD, MCI and healthy controls. No significant changes in hematologic parameters were observed across these diagnostic groups. Discussion: The present study provides additional evidence that folic acid is reduced in patients with AD and reinforces the importance of nutritional changes, in particular the one-carbon metabolism, in the physiopathology of AD. Almeida CC, et al. / Rev Psiq Clin. 2012;39(3):90-3
Sudden Death in Indeterminate Chagas disease is Uncommon. A Systematic Review

Chagas disease is a serious health care problem in Latin America due to its high prevalence, morbidity and mortality. The migration from Latin American countries to the United States and Europe has disseminated a significant number of infected subjects. Most patients present the indeterminate form of the disease and remain without symptoms for decades. However, some groups believe that patients with the indeterminate form are at high risk for developing sudden death although no studies have been designed to investigate this issue. We conducted a systematic review of follow-up studies in patients with asymptomatic Chagas disease, normal ECG and known cause of death. We found 15 articles including 9382 patients. Mortality rate in asymptomatic patients with normal ECG was very low (0.92%) and similar to that of controls without Chagas disease (p=0.38). This systematic review shows that sudden death is uncommon in the indeterminate form of the disease and that the risk of death is similar to that of the general population. Thus, these patients should be allowed to lead a normal working life and to practice physical activity, without alarming them unnecessarily about their condition or indicating sophisticated and expensive studies. Regular follow-up is necessary as the death risk increases considerably when the disease progresses to the cardiac form.
A study on the blood levels of homocysteine, fibrinogen and hsCRP in diabetic patients with ischaemic stroke from eastern India

Introduction: Diabetes is an important risk factor for ischaemic stroke. Newer risk markers like C - reactive protein, fibrinogen and homocysteine levels are now being considered for better risk predication. Aim: To study these new risk markers in diabetic patients with ischaemic stroke and to study any association of these markers with other blood parameters. This was thus a case control study. Methods: Patients who were proved (by imaging) to be suffering from cerebral ischaemic events were chosen after proper screening and after their consent was taken. The diabetic subset was compared with the non-diabetic subset by doing blood tests which included blood glucose, lipids and newer markers. This was done 2 months after the index event to avoid false positive results. Statistical analysis: We analyzed the data by using online software. Pearson’s correlation coefficient was used for finding the correlation between the variables. Results: 82 patients were included in the study, of which 42 were diabetic (ADA Criteria). The diabetic subset had significantly higher levels of total serum cholesterol (186 ± 50.3 vs. 167± 30.6; p=0.041) and LDL levels (112 ± 33.3 vs. 92± 15.2; p=0.0008). The triglyceride levels were also higher (165± 19.35 vs. 124.6± 9.22; p=0.0010). The HsCRP and fibrinogen levels were higher in diabetic patients with ischaemic stroke (p 110 mg/dl had a high sensitivity in predicting high levels of plasma homocysteine. The logistic regression model showed that hsCRP had the strongest correlation with increasing age (OR=1.1). Conclusion: This case control study has shown significantly higher hsCRP and fibrinogen levels in ischaemic stroke patients who had diabetes, as compared to the non-diabetic subsets. These newer parameters were also correlated with blood glucose and the lipid values. Thus, these can be used as surrogate markers in diabetic patients for the prediction of ischaemic stroke. However, a prospective study is needed to identify the risk factors and their predicative value better.