Miracle-dz/UniFAR-FTUs huggingface dataset:
Zu den rezenten studien im hattischen: eine zwischenbilanz

Hatti Dili ara s t i rmalar i , 2004 y i l i nda yay i nlanan Hatti Dili kelime hazinesini konu alan kitab i n (HWHT) yay i nlanmas i ndan bu yana oldukca h i zlanm i s t i r. Hem Hattice iceren Bo g azkoy metinlerinin tamam i na yak i n i n i n art i k yay i nlanm i s olmas i , hem de son y i llarda bu dili konu alan onemli cal i s malar i n yap i lmas i sonucunda, uzun y i llard i r bir cumlesi bile tam tercume edilemeyen Hattice’nin yava s yava s anla s i l i r bir dil olma ozelli g ine kavu s tu g unu sevinerek goruyoruz. Ozellikle cift dilli Hattice- Hititce metinler sayesinde yuzden fazla Hattice kelimenin kar s i l i g i bugun bilinmektedir. Bununla birlikte, Hattice ve bu dilin Eski Anadolu kulturundeki etkilerinin anla s i lmas i icin, filolojik bak i mdan ve metin yorumlanmas i ba g lam i nda daha ciddi ad i mlar i n at i lmas i gerekmektedir.
Clinical & therapeutical study on inactive ovaries in Holstein-Friesian cows by using GnRH analogues

This study was performed on 45 lactating Holstein – Friesian cows suffered from inactive ovaries for three months post partum and diagnosed clinically by rectal palpation in the form of the college of Agriculture / University of Baghdad , their ages 3-5 years during the period from 2010-2012. These cows were divided randomly into 4 groups, 1 st group (12 cows) were injected with 0.021mg (5 ml) Receptal I/M, 2 nd group (12 cows) were given 500 μg (5ml) Cystorelyin I/M, 3 rd group (12 cows) injected with 0.5 mg (5 ml) Fertagil I/M in one dose and 4 th group (9 cows) without treatment (control group). The response rate was 91.8%, 83.3%, 91.6% and 66.6% for the four groups respectively. While the duration of response (from treatment to oestrus appearance) was 7.43±1.56, 10.66±2.37, 8.44±2.41 and 67.63±9.87 in the 1 st ,2 nd ,3 rd and 4 th groups respectively, but the pregnancy rate recorded 90.9%, 80%, 81.8% and 83.3%. The statistical analysis showed that the 1 st and 3 rd group was recorded significant differences higher (p<0.01) than other groups (2 nd and 4 th ) related with responsive animal and the duration of response also but the pregnancy rate recorded higher significance (p<0.01) compared with 2 nd , 3rd and 4 th groups. The number of services /conception was more than 1.5-2.5 for all groups & not significant, the days open recorded higher significant (p<0.01) in 1 st , 2 nd and 3 rd compared with 4 th group (control group).
The costs of mating and mate choice in water striders

Abstract Abstract. Predation risk associated with the various components of the mating behaviour of the water strider Gerris buenoi are investigated with a series of experiments. Mating behaviour in this species includes frequent harassment of females by males (mate searching), pre-mating struggles that may function as mate choice by females, mating which includes copulation and male mate guarding, and post-mating struggles. Each component of the mating behaviour of females increases predation risk. Escape by females from harassment by males increases the movement rate of females and predacious backswimmers are attracted to movement at the water surface. Capture success of backswimmers is almost tripled on females engaged in pre- and post-mating struggles relative to single females. Because longer pre-mating struggles are one mechanism by which females bias the mating success of male phenotypes in water striders, these data demonstrate that mate choice is costly to females. Finally, mating females are at twice the risk of predation than are single females. Some components of mating behaviour in males also appear to increase predation risk. Males searching for mates spend a higher portion of their time in the open water habitat (out of refuge) and move more often than females. Use of the open water habitat increases exposure to backswimmers and movement on the surface attracts backswimmers. Males that successfully grasp females engage in pre-mating struggles, during which capture success by backswimmers on males is significantly increased. However, in contrast to females, there was no significant increase in capture success of backswimmers on mating relative to single males.
American men and women of science

Want to get experience? Want to get any ideas to create new things in your life? Read american men and women of science now! By reading this book as soon as possible, you can renew the situation to get the inspirations. Yeah, this way will lead you to always think more and more. In this case, this book will be always right for you. When you can observe more about the book, you will know why you need this.
Présentation multimodale et contextuelle de l'information

Cette these s’inscrit dans le domaine de la communication Homme-Machine et plus precisement dans celui de la multimodalite en sortie. Elle a pour theme l’adaptation des sorties d’un systeme multimodal au contexte d’interaction. Les travaux de recherche presentes decrivent les problemes rencontres dans la conception d’une presentation multimodale et contextuelle de l’information et proposent une approche de resolution conceptuelle et logicielle. Ce travail se divise en trois phases. La premiere, introduit le modele conceptuel WWHT permettant une presentation adaptee de l’information. Ce modele s’appuie sur quatre concepts fondamentaux : "What", "Which", "How" et "Then", annotant les evenements marquants du cycle de vie d’une presentation multimodale. Ces concepts structurent les processus de conception et d’evolution de la presentation en integrant le contexte d’interaction dans leurs mecanismes de decision. Inspiree de ce modele, la seconde phase introduit une plateforme logicielle permettant la conception iterative des sorties d’un systeme multimodal. Cette plateforme intitulee ELOQUENCE accompagne le concepteur tout au long du processus de conception, en outillant les differentes phases de son cycle de vie. Une derniere phase applique cet environnement de conception a trois applications de domaines differents : telephonie mobile, avionique militaire et controle aerien. Ces applications incarnent un processus de validation logicielle visant a evaluer incrementalement la faisabilite des concepts emis. De ces experimentations ressortent des resultats encourageants, ouvrant de nouvelles perspectives sur l’interaction multi-utilisateur et l’informatique ambiante.
Principles and Practice of Geriatric Psychiatry

Agronin ME, Maletta GJ, eds. 800 pages. Philadelphia: Lippincott, Williams & Wilkins; 2005. $149.00. ISBN 0781748100. Order at www.lww. com. Fields of medicine: Primary care and specialities. Format: Hardcover book. Audience: Clinicians treating older people. Selected chapters may be worthwhile for ethicists, lawyers, and clergy. Purpose: To review what is currently known, both clinical and scientific, about behavioral and psychological dysfunction in older people, and to foster continued advocacy for the new field of geriatric psychiatry. Content: Forty-three chapters cover such topics as forensics, palliative care, spirituality, ethics, sex, intellectual disabilities, and pain. The 104 authors include well-known leaders in the field, respected academics, and experienced clinicians. Highlights: The best parts of this book include the helpful, illustrative, real-life case examples in every chapter, the tables and figures, and the extensive listing of resources for patients, families, and caregivers. Chapters are relatively short, and it is easy to look things up or find a specific topic. The forensics chapter is a minicrash course and review of the most relevant principles. The hospicepalliative care chapter highlights the need for a greater focus on symptom-oriented care in medicine in general and includes a helpful review of current knowledge regarding the burdens and benefits of interventions in long-term care. The chapter on depression and Alzheimer disease is a gem. Basic science information is linked well to etiologic and therapeutic implications. Capacity assessment and decisional competence, 2 challenges faced by both geriatric psychiatrists and ethics committees, are well-covered in the ethics chapter. The sex chapter is a delight and the only one that focuses on the positive aspects of aging. Limitations: The book would be strengthened by a chapter on gender, pulling together what we know about gender differences in older adults, and a chapter on health, wellness, and successful aging. There is also little discussion of the American system of health care financing and its impact on older people. Related Readings: With its many authors from over a dozen disciplines, this book has a broader scope than other standard texts, such as Blazer and colleagues' Textbook of Geriatric Psychiatry, 3rd edition (American Psychiatric Publishing, 2004).
Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow‐ and pressure‐induced arterial remodeling in mice

The arterial wall adapts to alterations in blood flow and pressure by remodeling the cellular and extracellular architecture. Biomechanical stress of vascular smooth muscle cells (VSMCs) in the media is thought to precede this process and promote their activation and subsequent proliferation. However, molecular determinants orchestrating the transcriptional phenotype under these conditions have been insufficiently studied. We identified the transcription factor, nuclear factor of activated T cells 5 (NFAT5; or tonicity enhancer‐binding protein) as a crucial regulatory element of mechanical stress responses of VSMCs. Here, the relevance of NFAT5 for arterial growth and thickening is investigated in mice upon inducible smooth muscle cell (SMC)‐specific genetic ablation of Nfat5. In cultured mouse VSMCs, loss of Nfat5 inhibits the expression of gene sets involved in the control of the cell cycle and the interaction with the extracellular matrix and cytoskeletal dynamics. In vivo, SMC‐specific knockout of Nfat5 did not affect the general vascular architecture and blood pressure levels under baseline conditions. However, proliferation of VSMCs and the thickening of the arterial wall were inhibited during both flow‐induced collateral remodeling and hypertension‐mediated arterial hypertrophy. Whereas originally described as a hypertonicity‐responsive transcription factor, these findings identify NFAT5 as a novel molecular determinant of biomechanically induced phenotype changes of VSMCs and wall stress‐induced arterial remodeling processes. —Arnold, C. , Feldner, A. , Zappe, M. , Komljenovic, D. , De La Torre, C. , Ruzicka, P., Hecker, M. , Neuhofer, W. , Korff, T. Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow‐ and pressure‐induced arterial remodeling in mice. FASEB J. 33, 3364–3377 (2019). www.fasebj. org
Predictors of Adverse Outcome Early After ICU Discharge

Objective: Clinicians are often confronted with the timely discharge decision, in order to avoid readmission and escalation of costs. Aim of the present study was to determine potential risk factors for ICU readmission or death early after ICU discharge. Methods: One hundred fifty-four ICU discharged patients were divided into three outcome groups according to whether they were readmitted (Group A, n = 13), or died within 72 h after ICU discharge (Group B, n = 11), or were not readmitted or died within 72 h (Group C, n = 130). Results: Patients being readmitted to the ICU had significantly longer prior length of stay in a ward compared to the group with positive outcome after ICU discharge (median: 12 vs. 2 days, p = 0.023). Patients with early post discharge death had received vasopressor support with norepinephrine for significantly longer period of time and were significantly more severely diseased at the day of discharge, based on APACHE II calculation. Rates of tracheostomy, central venous catheter, nasogastric nutrition and colonization with an MDR organism, along with hemodynamic and respiratory parameters at ICU discharge were similar among the outcome groups. Nonetheless, the prevalence of patients with Glasgow Coma Scale (GCS) < 13 was significantly higher in Group B. The principal cause of ICU readmission was sepsis (8/13 patients), whereas of early mortality was acute respiratory failure (9/11 patients). Conclusions: Patients with higher disease severity at discharge and moderately altered mental status, especially those with prolonged hospitalization and vasopressor support are at increased risk for ICU readmission or early post discharge mortality.
Analysis of Operation Performance in the Process of Machine Wood Harvesting with Fao Far 6840 Mini-Harvester

Abstract The article presents analysis of operation of Fao Far 6840 mini harvester for machine wood harvesting. Analysis was made based on working day timing. The investigations were carried out on the area of Lubliniec Forest Inspectorate, Bór Forestry on the habitat forest site − fresh mixed forest where pine wood was obtained with the use of a harvester. Timing was carried out based on the registration of the exploitation time of a harvester with the use of a video camera and stopwatch and measurements of the obtained size grade. Based on the obtained results low values of performance in the exploitation change time 9.61 m3·h−1, and effective performance 12.14 m3·h−1 were reported. Low machine performance was affected mainly by conditions of harvesting, low log volume (at the average 0.62 m3) and concentration of trees. The head structure (applied feed system), weak work organization (short time of a single 6 hour shift) and weak skills of the machine operator were additional factors that reduced the performance
Classificação, densidade e parâmetros nutricionais do milho.

As dietas normalmente formuladas para aves e suínos no Brasil possuem milho em sua constituição. A variação na composição em nutrientes de diferentes partidas de milho e a presença de grãos avariados, como por exemplo, grãos ardidos, quebrados, carunchados, matérias estranhas e impurezas afetam a qualidade do grão. Assim, torna-se importante a adoção de metodologias que objetivem avaliar os diferentes lotes de grãos, tornando-se possível a formulação de dietas com maior precisão (SILVA et al., 2011). O espectrofotômetro de reflectância no infravermelho próximo (NIR) pode ser utilizado para a análise quantitativa e qualitativa dos alimentos, sendo um método rápido e preciso na determinação dos compostos orgânicos dos ingredientes (GONTIJO NETO et al., 2009). Por outro lado, o Ministério da Agricultura, Pecuária e Abastecimento – MAPA estabelece definições para classificação de partidas de milho, baseadas em características como grãos ardidos, quebrados e impurezas (Portaria 845, 1976), visando a obtenção de lotes de milho mais homogêneos e de melhor qualidade. A determinação da densidade não é uma análise definida no método de classificação, mas é útil por apresentar alta correlação positiva com o nível energético do milho. Muitas vezes os nutricionistas são obrigados a trabalhar com as matrizes nutricionais estáticas por não possuirem ferramentas para o controle de qualidade das matérias primas. A classificação de partidas de milho e a análise da sua composição química podem assumir fundamental importância quando deseja-se trabalhar com nutrição de precisão. Assim, a busca de ferramentas para auxiliar a formulação de dietas com níveis mais exatos de nutrientes pode constituir em tecnologias importantes para a redução dos custos de produção das dietas para os animais. Dessa forma, o objetivo deste estudo foi determinar a correlação entre os parâmetros de classificação, densidade, proteína bruta, extrato etéreo e matéria seca de amostras de milho.
Electrical Tree Characteristics in SIR/MMT Nano-composite under Repetitive Pulse Voltage

The electrical tree in cable accessories is a threat to cable system. The nano-composite has been proven to be a solution to inhibit the electrical tree. In this paper, a nano-composite of silicone rubber (SIR) and nano montmorillonite (MMT) was prepared to improve the electrical tree resistance of the SIR material. The nano MMT was added into SIR and treated by a high DC electric field for the orientation of MMT when the SIR was in liquid state. A needle-plate electrode and repetitive pulse voltage were employed to initiate electrical tree in this nano-composite. The electrical tree inception probability was recorded and its growth process was captured by using a digital microscope system. The experiment results indicates that the inception probability is decreased by the addition of nano MMT. And the electric field inducement decreases the threshold of MMT content to inhibit tree growth. The addition of MMT and inducement change the structure of electrical tree. The electric tree is shorter with the addition of MMT and the number of branches is smaller after the electric field inducement.
Low-Dose Vigabatrin (γ-Vinyl GABA)-Induced Damage in the Immature Rat Brain

Abstract The antiepileptic drug, vigabatrin, inhibits GABA transaminase, thus elevating GABA levels in the brain. In adult animal experiments, high-dose (200 mg/kg/day) chronic vigabatrin administration is associated with potentially reversible myelin vacuolation, a phenomenon not documented in humans. We hypothesized that vigabatrin might adversely affect myelination in the developing brain. Rats were given vigabatrin in doses comparable to those used clinically (15–50 mg/kg/day), from age 12 to 16 days. The rats were killed at age 19–20 days. We observed decreased myelin staining in the external capsule, axonal degeneration in white matter, evidence of glial cell death in the white matter, and reactive astrogliosis in the frontal cortex. We did not detect myelin vacuolation. These findings indicate that vigabatrin can have adverse and potentially irreversible effects on the developing rat brain. The mechanism of damage could be direct toxicity of vigabatrin or an indirect effect mediated through elevated GABA levels. Vigabatrin has been recommended as a treatment for some forms of childhood epilepsy; therefore, further studies are needed to assess the risks in children.
Crystal structures of the N-terminal domain of the Staphylococcus aureus DEAD-box RNA helicase CshA and its complex with AMP.

CshA is a DEAD-box RNA helicase that belongs to the DExD/H-box family of proteins, which generally have an RNA-dependent ATPase activity. In Staphylococcus aureus, CshA was identified as a component of the RNA degradosome and plays important roles in RNA turnover. In this study, the crystal structures of the N-terminal RecA-like domain 1 of S. aureus CshA (SaCshAR1) and of its complex with AMP (SaCshAR1-AMP) are reported at resolutions of 1.5 and 1.8 Å, respectively. SaCshAR1 adopts a conserved α/β RecA-like structure with seven parallel strands surrounded by nine α-helices. The Q motif and motif I are responsible for the binding of the adenine group and phosphate group of AMP, respectively. Structure comparison of SaCshAR1-AMP and SaCshAR1 reveals that motif I undergoes a conformational change upon AMP binding. Isothermal titration calorimetry assays further conformed the essential roles of Phe22 in the Q motif and Lys52 in motif I for binding ATP, indicating a conserved substrate-binding mechanism in SaCshA compared with other DEAD-box RNA helicases.
A NOVEL APPROACH FOR ESTIMATING THE ARL-BIAS SEVERITY OF SHEWHART P-CHARTS

The Shewhart p-Chart is a widely used and taught control chart that monitors the process fraction of nonconforming, p. The control limits of this chart are computed from an equation derived from the central limit theorem that assumes the parameters p and sample size, n, provide a good approximation of the binomial to the normal distribution. It is known that if the approximation is poor the chart becomes ARL-biased with a consequent deterioration of its process improvement detection capability. Hence, if one is to use this chart its ARL-biased severity ought to be established in advance. Three parameters are used to estimate a chart ́s ARL-bias severity, namely the in-control ARL, the relative ARL-bias and the maximum out of control ARL. However, calculating these parameters is a task that requires of lengthy calculations that often entails the use of specialised software. In this paper we present a new approach that facilitates the estimation of the bias severity, this approach consists of a closed-form equation that eases the calculations of the ARL-bias parameters and of a graphical method that permits assessing a p-Chart ́s ARL-bias severity level according to the severity zone in which its n and p values fall into.
An Overview of the National Cancer Institute's Initiatives to Accelerate Rural Cancer Control Research

This article is featured in Highlights of This Issue, [p. 1237][1] A recent publication by the Centers for Disease Control and Prevention (CDC; ref. [1][2]) reported that nonmetropolitan rural counties had lower 5-year annual age-adjusted cancer incidence rates (2009–2013), but higher average
Individualized Follow-Up Strategy for Patients with an Indeterminate Response to Initial Therapy for Papillary Thyroid Carcinoma.

BACKGROUND The concept of a dynamic risk-stratification scheme has been suggested for individualized management of patients with papillary thyroid carcinoma (PTC). However, there is no specified follow-up strategy for patients with an indeterminate response. METHODS This study evaluated 403 PTC patients who had an indeterminate response during the first 12-24 months after initial therapy. All patients underwent total thyroidectomy with radioactive iodine remnant ablation. Patients were further classified into three groups based on risk of structural persistence/recurrence: a Tg+ group (detectable thyroglobulin [Tg], regardless of antithyroglobulin antibody [TgAb] or imaging findings; 196 patients), a TgAb+ group (positive results for TgAb with undetectable Tg, regardless of imaging findings; 46 patients), and an Image+ group (nonspecific findings on neck ultrasonography or faint uptake in the thyroid bed on whole-body scan, with undetectable Tg and negative results for TgAb; 161 patients). RESULTS With a median of 9.6 years (interquartile range 7.7-11.2 years) of follow-up, 56 (14%) PTC patients had structural persistent/recurrent disease: 50 (89%) at locoregional sites and six (11%) at distant sites. The recurrence rate in Tg+, TgAb+, and Image + groups were 26.5%, 8.7%, and 0%, respectively. The median time to detection of structural persistent/recurrent disease from the initial thyroid surgery was 3.7 years (interquartile range 2.5-6.3 years). The optimal cutoff stimulated Tg level to predict structural persistent/recurrent disease was 3.1 ng/mL in the Tg+ group. This classification system revealed higher predictability of structural persistent/recurrent disease than the tumor-node-metastasis staging system and American Thyroid Association risk stratification (proportion of variation explained: 15.7% vs. 2.4% and 0.9%, respectively). Six (3%) patients with distant metastatic disease were all classified in the Tg+ group, and all had lung metastasis. CONCLUSIONS The findings suggest a more individualized follow-up strategy for patients with an indeterminate response. More careful evaluation, including early evaluation of distant metastasis, is necessary in patients with elevated Tg levels. However, for patients testing positive for TgAb or those with only nonspecific imaging findings, regular follow-ups of Tg and TgAb levels and neck ultrasonography are sufficient.