Miracle-dz/UniFAR-FTUs huggingface dataset:
Range‐wide population genomics of the Mexican fruit fly: Toward development of pathway analysis tools

Recurrently invading pests provide unique challenges for pest management, but also present opportunities to utilize genomics to understand invasion dynamics and inform regulatory management through pathway analysis. In the southern United States, the Mexican fruit fly Anastrepha ludens is such a pest, and its incursions into Texas and California represent major threats to the agricultural systems of those regions. We developed a draft genome assembly for A. ludens, conducted range‐wide population genomics using restriction site‐associated DNA sequencing, and then developed and demonstrated a panel of highly differentiated diagnostic SNPs for source determination of intercepted flies in this system. Using 2,081 genomewide SNPs, we identified four populations across the range of A. ludens, corresponding to western Mexico, eastern Mexico/Texas, Guatemala/Belize/Honduras, and Costa Rica/Panama, with some intergradation present between clusters, particularly in Central America. From this population genomics framework, we developed a diagnostic panel of 28 highly differentiated SNPs that were able to recreate the genomewide population structure in this species. We demonstrated this panel on a set of test specimens, including specimens intercepted as part of regular trapping surveillance in Texas and California, and we were able to predict populations of origin for these specimens. This methodology presents a highly applied use of genomic techniques and can be implemented in any group of recurrently invading pests.
Effect of Shen Tao Ruangan Pill for Postoperative Recurred Liver Cancer

【Objective】To investigate the therapeutic effect of Shen Tao Ruangan Pill(STRP) for postoperative recurred liver cancer by a randomized and controlled trial. 【Methods】Forty patients with postoperative recurred liver cancer were equally randomized into groups A and B.The two groups received routine symptomatic treatment,and group A was additionally treated with STRP(mainly composed of Herba Artemisiae Scopariae,Herba Hedyotis Diffusae,Herba Scutellariae Barbatae,Rhizoma Curcumae,Semen Persicae,Radix Angelicae Sinensis,Radix Salviae Miltiorrhizae,Radix Ginseng,Poria,Carapax et Plastrum Testudinis) and group B with Pingxiao Capsule.After 3-month treatment,the therapeutic effect was evaluated in the two groups. 【Results】(1)After treatment,the symptoms were relieved in both of groups A and B,and group A had a better effect in relieving abdominal distention,anorexia and lassitude than group B(P0.05). (2) Grading of Karnofsky scores and hepatic reserved function in group A were superior to those in group B,the difference being significant(P0.05). The differences of alpha-fetoprotein(AFP) decrease and the change of tumor mass were insignificant between groups A and B(P0.05). (3) The non-progressive survival period was(172±11.64) days in group A and(143±10.95) days in group B;the survival rate within 3,6 and 10 months was 82.31%,70.42% and 50.33% in group A respectively,and 72.70%,65.70% and 46.33% in group B respectively;the median survival time was(203±20.87) days in group A and(167±19.58) days in group B,the difference being significant(P0.05). 【Conclusion】STRP is effective in relieving symptoms,improving body function and hepatic reserved function,counteracting tumor growth,and prolonging the non-progressive survival period and the median survival time for postoperative recurrence in primary liver cancer.
PARA ALÉM DO DUALISMO NATUREZA/CULTURA: FICÇÕES DO CORPO FEMININO

this text probes into the legacy of a central dualism of western culture – nature vs. culture – to examine how the tropo of the “natural woman” constructed in the modern period bears upon the narrative logics of two representative European novels of the XIX century: Gustave Flaubert’s Madame Bovary and Leon Tolstoi’s Ana Karenina. Then, it focuses on some scenes of Kate Chopin´s The awakening and Virginia Woolf`s To the lighthouse to show to what extent the representation of the female characters’ experience of corporeality des-figure the dualisms upon which traditional cultural gender norms are predicated and, therefore, subvert the inscription of the body as the locus of the reproduction of femininity.
An Occupational Therapy Intervention Service to Hostels for Homeless People: An Overview

This evaluation of an Occupational Therapy Intervention Service within homeless persons' hostels in Bristol, England, highlights the efficacy of occupational therapy with this service user group and reflects on the practicalities of delivering such a service in an inter-agency context. Occupational therapy engaged homeless individuals with complex needs who were often defended against change in their own lives. Over 7 months an Occupational Therapy Intervention Service provided an individual service for 16 residents and made a further 542 contacts through group work. The creation of psychosocial microenvironments within hostels allowed individuals to experience themselves differently and contemplate the possibility of change. The importance of collaborative working between occupational therapists and hostel staff is examined in the light of the psychologically informed environments agenda.
Probabilistic analysis of defect tolerance in asynchronous nano crossbar architecture

Among recent advancements in technology, nanotechnology is particularly promising. Most researchers have begun to focus their efforts on developing nano scale circuits. Nano scale devices such as carbon nano tubes (CNT) and silicon nano wires (SiNW) form the primitive building blocks of many nano scale logic devices and recently developed computing architecture. One of the most promising nanotechnologies is crossbar-based architecture, a two-dimensional nanoarray, formed by the intersection of two orthogonal sets of parallel and uniformly-spaced CNTs or SiNWs. Nanowire crossbars offer the potential for ultra-high density, which has never been achieved by photolithography. In an effort to improve these circuits, our research group proposed a new Null Convention Logic (NCL) based clock-less crossbar architecture. By eliminating the clock, this architecture makes possible a still higher density in reconfigurable systems. Defect density, however, is directly proportional to the density of nanowires in the architecture. Future work, therefore, must improve the defect tolerance of these asynchronous structures. The thesis comprises two papers. The first introduces asynchronous crossbar architecture and concludes with the validation of mapping a 1-bit adder on it. It also discusses various advantages of asynchronous crossbar architecture over clock based nano structures. The second paper concentrates on the probabilistic analysis of asynchronous nano crossbar architecture to address the high defect rates in these structures. It analyzes the probability distribution of mapping functions over the structure for varying number of defects and proposes a method to increase the probability of successful mapping.
How Do Drivers Allocate Their Potential Attention? Driving Fixation Prediction via Convolutional Neural Networks

The traffic driving environment is a complex and dynamic changing scene in which drivers have to pay close attention to salient and important targets or regions for safe driving. Modeling drivers’ eye movements and attention allocation in traffic driving can also help guiding unmanned intelligent vehicles. However, until now, few studies have modeled drivers’ true fixations and allocations while driving. To this end, we collect an eye tracking dataset from a total of 28 experienced drivers viewing 16 traffic driving videos. Based on the multiple drivers’ attention allocation dataset, we propose a convolutional-deconvolutional neural network (CDNN) to predict the drivers’ eye fixations. The experimental results indicate that the proposed CDNN outperforms the state-of-the-art saliency models and predicts drivers’ attentional locations more accurately. The proposed CDNN can predict the major fixation location and shows excellent detection of secondary important information or regions that cannot be ignored during driving if they exist. Compared with the present object detection models in autonomous and assisted driving systems, our human-like driving model does not detect all of the objects appearing in the driving scenes, but it provides the most relevant regions or targets, which can largely reduce the interference of irrelevant scene information.
Super Mario Bros.

Forward Preface Acknowledgements INTRODUCTION CONTEXTS 1-1 An Unlikely Hero is Born 1-2 Mario Grows Up 1-3 Kondo's Compositional Philosophy 1-4 Kondo's Instruments MUSIC 2-1 Overworlds and Underworlds 2-2 The "Underwater" Waltz 2-3 Bowser's "Castle" Theme & Other Endings 2-4 Sound Effects CONCLUSION Bibliography Index
Exploring Rapid, Sensitive and Reliable Detection of Trace Explosives Using Paper Spray Mass Spectrometry (PS‐MS)

In this publication we work towards providing fast, sensitive and selective analysis of explosive compounds collected on swabs using paper spray mass spectrometry. We have (a) increased the size of the paper spray substrate to 1.6×2.1 cm for compatibility with current practise in swabbing for explosive material; (b) developed a method for determining a successful extraction of analyte from the substrate to reduce false negative events; and (c) expanded the range of analytes that can be detected using paper spray to include the peroxide explosive HMTD, as well as nitroglycerine (NG), picric acid (PA) and tetryl. We report the development of a 30 s method for the simultaneous detection of 7 different explosive materials using PSMS with detection limits below 25 pg, as well as detection of HMTD at 2500 pg, showing an improvement on previously published work.
Sensing and Visualizing Physiological Arousal

In order to create input devices that are capable of sensing and interpreting human affect from physiological measurements, most previous approaches have produced interfaces that are cumbersome and require overhead in setup and calibration. Our goal was to create a minimal interface that could still interpret human affect. The results from this input are visualized to inform the user about his or her own state. We describe our simple tangible interface that requires no configuration, minimal explanation, and does not require known actions from the user. This interface collects galvanic skin response (GSR) data and creates a visualization of this data.
Addition Of Coleus Amboinicus, L Leaf’s Extract In Ration To Percentage Of Carcass, Abdominal Fat, Liver And Heart Broiler

The purpose of this study was to determine the effect of giving coleus amboinicus, L leaf’s extract, on the percentage of carcass, liver, heart and abdominal fat and the level of coleus amboinicus,L extract which is appropriate in broiler feed. This research was conducted in labor and broiler enclosures of the Payakumbuh State Agricultural Polytechnic, from January to May 2018. The material was DOC, commercial food 311, corn, bran, soybean meal, fish meal and minerals, and the equipment used was cages and equipment. The design used is RAL with 6 treatments and 4 replications. The results obtained that the addition of coleus amboinicus, L extract, L did not affect significantly (P> 0.05) on the percentage of carcass and liver, while the administration of coleus amboinicus, L leaf’s extract significantly affected (P <0.05) on the percentage of heart and abdominal fat broiler. Giving a dry of coleus amboinicus leaf’s, L, 4 g / kg ration can reduce broiler abdominal fat.
Textural Properties of Newly Developed Cookies Incorporating Whey Residue

ABSTRACT Cookies vary considerably in composition, shapes, flavours or textures, being much appreciated by consumers, and providing easy ways of supplying nutrients and energy, besides bioactive components. The objective of this study was to develop new added-value cookies incorporating whey residue, which is a by-product from the dairy industry, thus finding alternative ways to avail this waste. The cookies were then evaluated for their textural characteristics by means of texture profile analysis. The results obtained revealed that the improved whey cookies were different that the other cookies, better looking and with better global appearance, and also presenting good textural properties, with low hardness and chewiness, allied to high springiness and cohesion, being thus suitable for elderly and children with increased eating difficulties. Furthermore, these properties were maintained along the storage period considered of 15 days, thus guarantying stability of the textural characteristics.
Effects of nanoparticles of zinc oxide on productive performance of laying hens. – a review.

Nanotechnology has the potential to revolutionize in poultry industry with new tools for the molecular treatment of diseases and enhancing the ability of animal to absorb nutrients and therefore improving productive performance response of poultry. The essential trace elements play important roles such as nutrients metabolism, antioxidant, component of numerous metalloenzymes and protein. Nanoparticles zinc oxide (Nano-ZnO) is the specially prepared mineral salt having particle size of 1 to 100 nm. It promotes growth can act as antibacterial agent, modulates the immunity and production of laying hens. Using of Nano-ZnO in laying hen's nutrition as nanoparticle size will help and improve the egg production sector. Therefore, the purpose of this study is to give an overview on the potential of Nano-ZnO as feed additives in laying hen diets, in order to explore the mechanism of the effects of Nano-ZnO supplementation on laying hen productive performance and to observe their influence on feed intake, ammonia emissions, digestibility, egg production, and egg quality.
Performance evaluation and optimization of Camellia sinensis extract as green corrosion inhibitor for mild steel in acidic medium

An essential method for protecting alloys and metallic material against corrosion in various media is the use of inhibitors. Several synthetic compounds exhibiting anticorrosive features are extremely toxic. Accordingly; tendency of using naturally occurring products as green corrosion inhibitors is originated. In this work, the effect of different parameters such as concentration of Camellia sinensis (green tea) extract, immersion time and temperature on the corrosion of mild steel in 1.0 M HCl was investigated gravimetrically and electrochemically by means of weight loss and potentiodynamic polarization techniques respectively. Besides, the current study aimed to optimize the corrosion inhibition efficiency of the Camellia sinensis extract by using a response surface methodology (RSM) modelling. After the optimization, the kinetic and thermodynamic parameters were performed. The inhibition efficiency was found to increase with increasing temperature and concentration of the extracts as well as the immersion time consequently; the chemical adsorption of the inhibitor extract on the metallic surface was proposed.
TGFβ drives mitochondrial dysfunction in peripheral blood NK cells during metastatic breast cancer

Natural Killer (NK) cells provide important protection from cancer and are a key requirement for particular immunotherapies. In activated NK cells, a metabolic response towards increased glycolysis and oxidative phosphorylation is crucial for NK cell effector functions. However, there is accumulating evidence that NK cells become dysfunctional during chronic inflammatory diseases, such as human breast cancer. This dysfunction is apparent in peripheral blood NK cells and can impact on normal NK cell immune responses and their effective targeting during immunotherapy. Herein, we demonstrate that prolonged cytokine stimulation combined with metabolic restriction, through inhibition of mTORC1, is sufficient to induce persistent dysfunction in human NK cells. TGFβ, also restricted NK cell metabolism and promoted persistent NK cell dysfunction. NK cells from patients with metastatic breast cancer had profound metabolic defects in glycolysis and mitochondrial function, and clear structural differences in NK cell mitochondrial morphology. Importantly, blocking elevated TGFβ improved readouts of metabolism and restored IFNγ production in patient NK cells.
Effect of Magnetized Water on Some Growth Characteristics of cowpea (Vigna unguiculata L.)

Two pot experiments were carried out at Faculty of Education, Alzaiem Alazhari University, Khartoum, to study the effect of magnetized water on some growth characteristics of cowpea. The experiments were set as a completely randomized design with three replications and four treatments. The treatments were water passed through magnetic funnel either, once, two, four or six times, compared with control (tap water). The results indicated significant differences in germination, plant height, number of leaves, leaf area, fresh and dry weight of shoot and root. Results also showed significant difference in chlorophyll content (a and b) and phosphorus and potassium content. Results indicated that magnetized water is an effective method for high yield of cowpea.
The role of premature evidence accumulation in making difficult perceptual decisions under temporal uncertainty

The computations and neural processes underpinning decision making have primarily been investigated using highly simplified tasks in which stimulus onsets cue observers to start accumulating choice-relevant information. Yet, in daily life we are rarely afforded the luxury of knowing precisely when choice-relevant information will appear. Here, we examined neural indices of decision formation while subjects discriminated subtle stimulus feature changes whose timing relative to stimulus onset (‘foreperiod’) was uncertain. Joint analysis of behavioral error patterns and neural decision signal dynamics indicated that subjects systematically began the accumulation process before any informative evidence was presented, and further, that accumulation onset timing varied systematically as a function of the foreperiod of the preceding trial. These results suggest that the brain can adjust to temporal uncertainty by strategically modulating accumulation onset timing according to statistical regularities in the temporal structure of the sensory environment with particular emphasis on recent experience.
Alternative Therapies To Relieve Symptoms Of Menopause

Alternative Therapies to Relieve Symptoms of Menopause By Traci M. Pelchat Washington State University, May 2004 Chair: Dr. Margaret Bruya: Women in menopause experience a plethora of aggravating symptoms. Symptoms range physiologically from hot flashes and depressive symptoms (feeling tense, irritable and depressed) to decreased bone mineral density (Kittell, Kemoff-Mansfield & Voda, 1998). Until recently, hormone replacement therapy (HRT) was the treatment choice for relieving ailing menopausal symptoms. In 2002, the Women's Health Initiative trial found corrlbination estrogen and progesterone (HRT) to be highly correlative with increased risk for stroke (41 %), breast cancer (26°k) and cardiovascular disease (29°k) (National Heart, Lung & Blood Institute [NHLBI], 2003). For the purpose of this review, a collaboration of evidence-based research on non-HRT therapies has been compiled to provide practitioners and women in menopause a better understanding of which options will help alleviate menopausal symptoms. Phytoestrogen and nonphytoestrogen products have proven to relieve certain menopausal symptoms, namely hot flashes (Freedman & Dinsay, 2000; Somekawa, Chiguchi, Ishibashi & Aso, 2002). Phytoestrogens that may work to relieve hot flashes are found in soy containing products such as isoflavones and tempeh (Somekawa et aI., 2001). Non-phytoestrogen produds that have been shown to relieve other menopausal symptoms such as depressive symptoms and increase bone density are found in donidine, melatonin, salmon calcitonin and raloxifene (Freedman & Dinsay, 2000).
Animal Research Biosafety

The use of laboratory animals as experimental models of disease has been a critical tool for biomedical researchers for decades. Animal studies allow scientists to discover and understand the mechanism of infection and ultimately to develop effective treatment and prevention modalities. Workers who directly handle infectious microbes or infected laboratory animals are at risk of exposure while performing their assigned duties. A comprehensive biosafety program, led by a biosafety professional, is critical to properly protect workers and the surrounding community. Such a program includes a thorough understanding of the biohazard through formal risk assessment, implementation of effective biohazard controls, and extensive training of all personnel who are at risk of exposure.
An XML Keyword Retrieval Algorithm Based on Nearest Pair

As more and more data are expressed and stored in XML format, the study on XML keyword retrieval becomes the focus of IR (information retrieval) and Database. This paper gives and proves some properties of SLCA (smallest lowest common ancestor), which is the key concept of XML keyword retrieval. It also introduces a new XML keyword retrieval algorithm, Nearest Pair, on the basis of the properties above. This algorithm uses the iterative bi-search technology to look for nearest pairs, which can decrease the assistant computation by one order of magnitude. The experimental results show that Nearest Pair outperforms the existing mainstream algorithms in
Antibiogram profile of Group B Streptococci isolated from bovine mastitis cases

Mastitis in bovines has become extremely complex and is one of the costliest disease in dairy industry. One important reason for treatment failure is assumed to indiscriminate use of antibacterial without testing in vitro sensitivity of causal organisms. This practice results in development of resistance to commonly used antimicrobials. To chalk out suitable antibiotic therapy, isolation and antibiotic sensitivity studies are always essential. Keeping these points in view the present study was undertaken to select a suitable antibiotic for treatment for Streptococcal mastitis. A total of 96 Streptococcal isolates were recovered from 261 milk samples collected from in and around Bangalore city, including fourteen milk samples from clinical mastitis cases which was confirmed by tuf gene based PCR. Out of 96 Streptococcal isolates, sixteen isolates including one reference strain were found to be S. agalactiae based on 16S rRNA and sip gene based PCR. The in vitro antibiogram study was conducted with fourteen antibiotics which were chosen according to their common use in research and veterinary practice. Investigation had shown that antibacterial susceptibility against S. agalactiae in following order, of sensitivity Ampicillin/ Sulbactum (94%), Chloramphenicol (81%), Gentamicin (69%), Ampicillin and Penicillin G (50%), Amoxycillin/Sulbactum and Streptomycin (37%), Piperacillin/Tazobactam (31%), Methicillin and Cefotaxime (25%), Enrofloxacin (19%), Ceftriaxone/Sulbactum and Ceftriaxone (12%) and Oxacillin (0%). Ampicillin/Sulbactum combination proved to be the drug of choice in this study.
A fast and effective segmentation algorithm for undersea hydrothermal vent image

This paper puts forward a segmentation algorithm for undersea hydrrothermal vent image. Basing on the in-depth analysis on the difference between sea-water area, rock and smoke area, which are the three kinds of objects in the typical undersea hydrothermal vent image, we employ both OTSU thresholding and Fuzzy C-Mean (FCM) clustering to segment the image, and discard all the non-interested area living only smoke area. Experiments show that this algorithm can segment the image both quickly and precisely.