Miracle-dz/UniFAR-FTUs huggingface dataset:
Can blended learning replace conventional learning in terms of mastery learning and cognitive attainment

Blended learning is a pedagogical approach that combines face-to-face learning with online learning. Blended learning is considered as the next conventional learning. So that education in Indonesia is not left behind, the issue of blended learning should have received an appropriate response because in many developed countries many have implemented blended learning as their conventional learning. This research aims to describe whether blended learning is able to replace face-to-face learning as conventional learning today. To describe this, this research was reviewed based on mastery learning and cognitive attainment. Mastery learning is used as a basis for reviewing because education standards in Indonesia use the standard “thorough learning”. The cognitive attainment is used as a basis for reviewing because cognitive levels influence the achievement of critical thinking skills where these skills are one aspect of the basic skills of the 21st century that students must master in this century. This research uses a quasi-experimental method with a non-equivalent design. The population of this research is students of favorite Islamic private elementary schools in Mojokerto. This research concludes that blended learning is able to replace face-to-face learning and is able to influence students’ cognitive attainment.
Relación de p v-aCO2/Da-vO2 con marcadores de hipoperfusión tisular y desenlace clínico, en pacientes en posoperatorio de cirugía cardiaca

Introduccion: La incidencia de Hipoxia Tisular Global es ampliamente conocida en pacientes en Posoperatorio de cirugia cardiaca y se asocia con mayor mortalidad y peores desenlaces. Objetivo: Establecer la relacion entre la diferencia venoarterial de CO2/Diferencia arteriovenosa de Oxigeno (p v-aCO2/Da-vO2), con variables de perfusion tisular y desenlaces clinicos, en pacientes en Posoperatorio de cirugia cardiaca. Diseno y metodos: Estudio longitudinal, prospectivo de julio de 2017 a febrero de 2018, en pacientes sometidos a cirugia cardiaca, con mediciones al ingreso a UCI (T0), a las 12 y 24 horas (T12 y T24), de: Saturacion venosa central (SvcO2), Base exceso (BEecf), diferencia venoarterial de CO2 (p v-aCO2), diferencia arteriovenosa de Oxigeno (Da-vO2), lactato arterial, Gasto Cardiaco (GC) , tasa p v-aCO2/Da-vO2 y desenlaces : dias de soporte vasoactivo, dias de ventilacion mecanica y dias estancia en UCI. Resultados: No se encontraron correlaciones significativas entre la tasa y los marcadores de perfusion tisular. La tasa no fue predictor independiente para ninguno de los desenlaces. La tasa disminuyo en el 84% de los pacientes; otro 10% presento elevacion simultanea de lactato, con mortalidad de 4%. La curva ROC mostro que en T0 y T12 la tasa mostro mayor AUC para identificar hiperlactatemia, con un punto de corte de 1,0. Conclusiones: La tasa mostro una tendencia a incrementar en pacientes con peores desenlaces, mostrando variaciones desde momentos iniciales de la reanimacion, relacionandose con la importancia para identificar hiperlactatemia. A la luz de la evidencia, se requieren mas estudios de evaluacion especificos para esta poblacion.
Regional Tourism Development Efficiency

This article is about the importance of increasing flow of tourists and its positive impact on the economy of the region as a whole. Today the sphere of tourism in our country is considered as one of the most important sectors of the economy and a significant factor in the development of regions. Solution of many problems in the regions, such as increase of labor employment, attraction of investments, improvement of ecological situation and others are connected with effective functioning of tourism sphere. Domestic and inbound tourism in the process of progress has a positive impact on the formation of the gross domestic product, thus ensuring an improvement in the quality and standard of living of the population. Thus, due to the growth of tourism activities and other service areas, it is possible to solve problems related not only to the improvement of economic indicators, but also to social, environmental and many others. It will be possible to talk about stable development of tourism in the region only when all conditions are fulfilled and companies start working as a whole. In case of deficiencies in one of the spheres, despite the coherence of work, tourism development will fall behind the predicted results. In such a situation the positive dynamics will be temporary. Thus, the main task is to create a single mechanism for all companies connected with this industry.
Sex-Limitation Models

Sex differences are common in the behavioral sciences. In addition to modelling mean, prevalence and variance differences, behavioral genetic sex-limitation models can identify the presence of both quantitative and qualitative sex differences. Quantitative sex differences refer to the fact that the proportion of variance due to genes, shared, and nonshared environment may differ between the sexes. Qualitative sex differences indicate whether the same or different genes or shared environment influence the two sexes. Models are described that test for both quantitative and qualitative sex differences in variation in the normal range, underlying liability of risk to disorder, and presence of an extreme group at one end of a distribution. Keywords: sex differences; genes; environment; model-fitting; liability
Song rate and duetting in the Chirruping Wedgebill (Psophodes cristatus): frequency, form and functions

ABSTRACT Much of our current understanding of song originates from studies of species living in seasonal environments, where breeding seasons are short and highly synchronised at the population level. By comparison, the form and function of song are less well understood in aseasonal environments, where breeding cycles are less predictable. We examined song rates of male and female Chirruping Wedgebills (Psophodes cristatus), a passerine endemic to the arid regions of inland, south-eastern Australia, across a 4 month period of breeding activity. Our results show that both males and females sing, and provide evidence of duetting. The song rate of male Wedgebills was highest in the early morning and during breeding and was substantially higher than the song rate of female Wedgebills. Over the course of the day, bouts of male singing were two orders of magnitude longer than females. By contrast, female song rate was independent of the time of day or reproductive phase. Females more often sang in tandem with their partners than expected by chance and duets occurred at a relatively low rate, independently of breeding phase. We discuss the possibility that male and female song and duets serve different functions.
Effect of pH and temperature on the carbonate promoted dissolution of sodium meta-autunite

This research evaluated the effect of aqueous bicarbonate on the uranium rate of release from natural Ca-autunite and quantified the process kinetic rate law for better prediction of the stability of autunite-group minerals. Testing was accomplished via a single-pass flow-through (SPFT) apparatus using buffered aqueous bicarbonate (0.0005 to 0.003M) at temperatures of 23° 90°C and pH values of 7 11. The release rate of uranium from Ca-autunite was directly correlated to increasing bicarbonate concentrations and showed strong pH dependency. Ca-autunite kinetic rate law parameters were compared to the values obtained for synthetic Na-autunite. The power law coefficient and intrinsic rate constant were higher at pH 9 11 for Ca-autunite than for Na-autunite. The lower stability of Ca-autunite was attributed to the high Ca-autunite surface cracking, fractures and basal plane cleavages as compared to Na-autunite and the formation of aqueous calcium uranium species, altering the solution saturation state.
[Primary cardiac tumors. Experience in 72 cases].

BACKGROUND Primary cardiac tumors have a low incidence, and their presentation form and clinical course are not well known. AIM To describe the characteristics, treatment, follow up and survival of patients with primary cardiac tumors (PCT). MATERIAL AND METHODS Review of all surgical procedures for PCT performed between 1984 and 2019 in a regional general hospital. The information was obtained from surgical protocols, surgical and pathology databases, medical records and registries of the Chilean National Identification Service. The clinical features of patients, immediate and long term outcomes are described. RESULTS Seventy-two surgical procedures for PCT were reviewed. Patients' age was 55 ± 15 years and 60% were women. The most common histological types were myxoma in 49 patients (68%), papillary fibroelastoma in 13 (18%) and sarcoma in 6 (8.3%). Forty-nine (68.1%) were symptomatic and all tumors were found on echocardiography. Fifty-one (71%) were in the left atrium, 10 (14%) in the aortic valve and eight (11%) in the right atrium. The surgical procedures were tumor resection in 48 patients (67%) and resection and repair with patch in 23 (32%). Mean postoperative stay was 6.6 ± 4.4 days, eight patients (11%) had complications and no patient died in the immediate postoperative period. Long term survival was higher in patients with benign PCT as compared with those with malignant tumors. CONCLUSIONS Most PCTs in this group of patients were benign neoplasms and the most common tumors were myxomas. The main diagnostic method is echocardiography and the prognosis of surgical treatment is excellent when the tumors are benign. (Rev Med Chile 2020; 148: 327-335).
Optimisation de formes pour les problèmes de contact en élasticité linéaire

This thesis deals with shape optimization for contact mechanics. More specifically, the linear elasticity model is considered under the small deformations hypothesis, and the elastic body is assumed to be in contact (sliding or with Tresca friction) with a rigid foundation. The mathematical formulations studied are two regularized versions of the original variational inequality : the penalty formulation and the augmented Lagrangian formulation. In order to get the shape derivatives associated to those two non-differentiable formulations, we suggest an approach based on directional derivatives. Especially, we derive sufficient conditions for the solution to be shape differentiable. This allows to develop a gradient-based topology optimization algorithm, built on these derivatives and a level-set representation of shapes. The algorithm also benefits from a mesh-cutting technique, which gives an explicit representation of the shape at each iteration, and enables to apply the boundary conditions strongly on the contact zone. The different steps of the method are detailed. Then, to validate the approach, some numerical results on two-dimensional and three-dimensional benchmarks are presented.
Antibiotic Resistance Genes in Various Environments

This mini-review addresses occurrence, fate, mechanisms and possible remediation of antibiotic resistant genes in various environments. While antibiotic resistant genes are widely spread via multiple mechanisms, they often cause various diseases and significantly influence on human health. Wastewater treatment plants among various environmental matrices are considered as the main reservoir of antibiotic resistant genes. Current wastewater treatment technologies have revealed the limitations for effective treatment of antibiotic resistance at wastewater treatment plants. Thus, innovative and cost-effective means to reduce antibiotic resistance in wastewater needs to be developed.
A külföldi tanulási motivációk és a felsőoktatással való elégedettség összefüggései

Kutatásunkban külföldi tanulmányi programban részt vevő hallgatók motivációs tényezőinek típusait és ezek elégedettséggel való kapcsolatát vizsgáltuk 20 külföldi hallgatóval készült mélyinterjú elemzésével. Eredményeink alapján hat motivációs csoport körvonalazódott: 1) társadalmi kényszer, 2) költséghatékony oktatás, 3) karrierépítés, 4) tanulmányok elmélyítése, 5) az adott ország megismerése és 6) élettapasztalat-szerzés. Azok a hallgatók, akik az ország megismerésére és élettapasztalat-szerzésre törekednek, sok esetben kihívásként tekintenek a külföldi tanulmányi program során tapasztalt nehézségekre, ami tovább növeli az elégedettségüket.
Ceftolozane/Tazobactam Susceptibility Testing in Extended-Spectrum Betalactamase- and Carbapenemase-Producing Gram-Negative Bacteria of Various Clonal Lineages

Nowadays, multidrug-resistant bacteria are considered as an increasing serious threat to public health worldwide. Global and local surveillance data are helpful in the application of the most efficient antimicrobial agent in bacterial infections. In the current study, we aimed to analyze the activity of the previously cleared agent ceftolozane/ tazobactam (C/T) in African and European multidrug-resistant Gram-negative bacteria. Susceptibility testing was performed on 147 extended-spectrum β-lactamase (107 Escherichia coli and 40 Klebsiella pneumoniae) and 103 carbapenemase-producing Gram-negative bacteria using Etest according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoints. Among the extended-spectrum β-lactamase producing isolates, 91 Escherichia coli isolates (85%) and 23 Klebsiella pneumoniae isolates (57.5%) were susceptible towards C/T whereas out of the 103 carbapenemase-producing isolates 102 (99.0%) were C/T-resistant. C/T should be included in susceptibility testing to fairly administer this antimicrobial agent in infections caused by multidrug-resistant bacteria. It may be considered as a therapy option for infections caused by extended-spectrum β-lactamase-producing bacteria once susceptibility to this antimicrobial combination has been confirmed.
Physiological regulation of high transpiration efficiency in winter wheat under drought conditions

Pot experiments were conducted to study the variation and physiological regulation of transpiration efficiency (TE) of four winter wheat (Triticum aestivum L.) varieties that are widely grown in different ecological regions in North China. Plants were grown under two soil moisture regimes, normal and drought stress. The results showed that under drought stress condition, both TE at plant level and TE at leaf level (TEl) increased significantly. The transpi ration rate (Tr) was reduced more strongly than leaf net CO 2 assimilation rate (Pn). The decline of Tr was mainly affected by stomatal conductance and the decline of Pn was affected by non-stomatal factors, which was confirmed by the decline in net photosynthetic oxygen evolution rate. The leaf soluble sugar content and proline content were significantly increased under drought stress. The stomatal density was increased and the stomatal length was re duced. These results led us to make the following conclusions: (1) Under drought stress, the increase in TEl appears to be regulated in two ways: via the stomata by regulating Tr, and independent of the stomata through regulation of Pn; regulation via the stomata was more sensitive; (2) Osmotic adjustment was closely correlated to the non-stomatal regulation, and stomatal aperture was closely correlated to the stomatal way.
Tissue structure accelerates evolution: premalignant sweeps precede neutral expansion

Cancer has been hypothesized to be a caricature of the renewal process of the tissue of origin: arising from (and maintained by) small subpopulations capable of continuous growth1. The strong influence of the tissue structure has been convincingly demonstrated in intestinal cancers where adenomas grow by the fission of stem-cell-maintained glands influenced by early expression of abnormal cell mobility in cancer progenitors2, 3. So-called “born to be bad” tumors arise from progenitors which may already possess the necessary driver mutations for malignancy4, 5 and metastasis6. These tumors subsequently evolve neutrally, thereby maximizing intratumoral heterogeneity and increasing the probability of therapeutic resistance. These findings have been nuanced by the advent of multi-region sequencing, which uses spatial and temporal patterns of genetic variation among competing tumor cell populations to shed light on the mode of tumor evolution (neutral or Darwinian) and also the tempo4, 7–11. Using a classic, well-studied model of tumor evolution (a passenger-driver mutation model12–16) we systematically alter spatial constraints and cell mixing rates to show how tissue structure influences functional (driver) mutations and genetic heterogeneity over time. This model approach explores a key mechanism behind both inter-patient and intratumoral tumor heterogeneity: competition for space. Initial spatial constraints determine the emergent mode of evolution (Darwinian to neutral) without a change in cell-specific mutation rate or fitness effects. Driver acquisition during the Darwinian precancerous stage may be accelerated en route to neutral evolution by the combination of two factors: spatial constraints and limited cellular mixing.
Extremal graphs for α- index

Let N(G) be the number of vertices of the graph G. Let Pl(Bi) be the tree obtained of the path Pl and the trees B1, B2, . , Bl by identifying the root vertex of Bi with the i-th vertex of Pl. Let Vm n = {Pl(Bi) : N(Pl(Bi)) = n;N(Bi) ≥ 2; l ≥ m}. In this paper, we determine the tree that has the largest α-index among all the trees in Vm n .
Genetic Assessment of Breeding Patterns and Population Size of the Sicklefin Lemon Shark Negaprion acutidens in a Tropical Marine Protected Area: Implications for Conservation and Management

The sicklefin lemon shark (Negaprion acutidens) is found in coastal waters of the Indo-West Pacific where it has been assessed by the IUCN as threatened with extinction. Information on the species’ reproductive ecology and local abundance, which are important considerations for effective management, remain limited. I used genetic analyses of tissue samples collected from juvenile N. acutidens, at the Curieuse Marine National Park (CMNP), Seychelles, between 2014-2017, to (1) estimate the number of adults reproducing at CMNP annually and (2) identify their breeding patterns through pedigree reconstruction. I report strong evidence of philopatry; primarily in females. Over the study period 25 reconstructed females produced multiple litters; the majority (88%) displayed biennial parturition. The remaining 12% displayed annual parturition. Multiple paternity was common (66% of 58 litters; mean number of sires per litter = 1.92). Convenience polyandry provides a likely explanation for this and may be driven by biased operational sex ratios during mating. Male philopatry to CMNP was low (17% of 114 reconstructed males) and may be influenced by habitat availability. Males likely breed over broader geographic scales than females. The breeding patterns I report are similar to those identified in other populations of lemon sharks and are likely applicable across the genus. In Seychelles, shark stocks are in decline due to overfishing. The high female philopatry in N. acutidens suggests protection of parturition sites, such as CMNP, is likely important to the conservation of local populations. However, adult life-stages, particularly males due to wider-ranging behaviour, are still subject to fishing pressure outside the park. Additional management measures are required to prevent further population declines. Species-specific management appears to be the best approach. The introduction of science-based fisheries control measures, for N. acutidens and other shark species, should be an urgent priority in the Seychelles.
Mechanism of Drug Resistance in Mycobacterium Tuberculosis

Mycobacterium tuberculosis the causative agent of tuberculosis has many intrinsic features which enable it to evade the activity of antibiotics. Many studies have been carried out to understand the mechanisms of drug resistance by this organism. An attempt was made in this write up to elucidate the various mechanism of drug resistance in M. tuberculosis, including its innate impermeable cell wall and mutation of specific genes. Drug resistance in Mycobacterium tuberculosis is not a product of a single homogeneous genetic unit. Rather it is as a result of frequent mutation in various genes which encode for resistance to antibiotics. Also, the slow metabolism during a prolonged dormant stage greatly enhances it resistance to drug, the waxy impermeable cell wall with the presence of numerous efflux pump are essential for withstanding the potency of antibiotics. Having an adequate knowledge on the molecular mechanisms of drug resistance in M. tuberculosis may be helpful in exploring new targets for drug development.
Evaluation of some anthropometric parameters of students on the site of the daloa university campus

The objective of this study is to assess the body mass index (BMI) of some students from the Jean Lorougnon Guede University in Daloa. The study was conducted on the Daloa campus and included 350 students of different gender and age. Anthropometric data such as weight (P), height (T), waist ratio (TT) and body mass index (BMI) were calculated. The boys in the study are mostly (171.34 ± 6.41 cm) taller than the girls (158.18 ± 5.47 cm), their body weight (64.01 ± 7.73 kg) is greater than that of girls (57.47 ± 9.42 kg). However, girls have a waist size (69.02 ± 7.49 cm) lower than that of boys (73.20 ± 5.23 cm). However, the BMI for girls (23.00 ± 3.85 kg / m2) is higher than that for boys (21.76 ± 1.92 kg / m2). The ratio (waist / waist) of girls (0.43 ± 0.04) is higher than that of boys (0.42 ± 0.02). This allowed us to show that the majority of students are normal weight, however some are overweight and others have abdominal obesity.
Respuesta al estrés de gramíneas polares y cultivos: la importancia de la inversión de los recursos en hoja

Climate change and the exponential increase in the world's population are causing the need to improve stress tolerance in crops to sustain food production. For this reason, this study analyzed physiological responses to stress due to water deficit, low temperatures and nutrient deficiency in 2 polar grasses: Deschampsia antarctica (Antarctic grass) from Antarctica and Poa pratensis (Poa of the meadows) from the high Arctic, compared to one of the world's most important cultivable grass species, wheat (Triticum aestivum). The objective of this study was to understand the response of photosynthesis at different temperatures at the level of structure and leaf nutrients. It was observed that the results of photosynthesis, in the 3 grasses, were influenced by low temperature and water deficit. The values of the LMA were affected by the low temperature in wheat and Poa pratensis, and by the water stress in Deschampsia antarctica. The relationship between photosynthesis and LMA was observed that it was significant.