Miracle-dz/UniFAR-FTUs huggingface dataset:
Alcohol-induced memory blackouts as an indicator of injury risk among college drinkers

Background An alcohol-induced memory blackout represents an amnesia to recall events but does not involve a loss of consciousness. Memory blackouts are a common occurrence among college drinkers, but it is not clear if a history of memory blackouts is predictive of future alcohol-related injury above and beyond the risk associated with heavy drinking episodes. Objective To determine whether baseline memory blackouts can prospectively identify college students with alcohol-related injury in the next 24 months after controlling for heavy drinking days. Methods Data were analysed from the College Health Intervention Project Study (CHIPS), a randomised controlled trial of screening and brief physician intervention for problem alcohol use among 796 undergraduate and 158 graduate students at four university sites in the USA and one in Canada, conducted from 2004 to 2009. Multivariate analyses used generalised estimating equations with the logit link. Results The overall 24-month alcohol-related injury rate was 25.6%, with no significant difference between men and women (p=0.51). Alcohol-induced memory blackouts at baseline exhibited a significant dose–response on odds of alcohol-related injury during follow-up, increasing from 1.57 (95% CI 1.13 to 2.19) for subjects reporting 1–2 memory blackouts at baseline to 2.64 (95% CI 1.65 to 4.21) for students acknowledging 6+ memory blackouts at baseline. The link between memory blackouts and injury was mediated by younger age, prior alcohol-related injury, heavy drinking, and sensation-seeking disposition. Conclusions Memory blackouts are a significant predictor of future alcohol-related injury among college drinkers after adjusting for heavy drinking episodes.
Impact of Transactional Analysis Group Training on Marital Satisfaction of Women's Referred to Counseling Centers and Cultural Centers of Isfahan

The present study examines the impact of transactional analysis training on marital satisfaction of women's referred to counseling centers and cultural centers in Isfahan. The current research is a type of quasi- experimental study with pre-test and post-test and with control group. The population consisted of 114 applicants participated in the training group were randomly selected and divided into two groups (30 women each). For both groups the ENRICH marital satisfaction test (short version) was used for the pre-test. The experimental group underwent 10 sessions of transactional analysis group training. In order to examine the data SPSS 15 was applied and the results were analyzed through multivariate covariance analysis test. the results showed that there is a difference in rate of marital satisfaction after the transactional analysis group training between the experimental and the control groups (p<0.01). Through training of women to get them familiarize with communicative and effective verbal and non-verbal interaction analysis many barriers to facilitation of a good relationship could be achieved.
Processing Sliding Mosaic Mode Data With Modified Full-Aperture Imaging Algorithm Integrating Scalloping Correction

Modified full-aperture imaging algorithm for sliding Mosaic mode synthetic aperture radar (SAR) is presented in this paper, which includes scalloping correction and spikes suppression. The full-aperture imaging algorithm is introduced into Mosaic mode and validated by real C-band airborne SAR imaging experiments. The main idea is to substitute zeros between bursts with linear-predicted data extrapolated from adjacent bursts to suppress the spikes caused by multibursts processing. Furthermore, scalloping correction for sliding Mosaic mode is integrated with this algorithm. It is innovational to correct the azimuth beam pattern weighting altered by radar antenna rotation in azimuth with deramping preprocessing operation. Finally, experiments performed by the C-band airborne SAR system with a maximum bandwidth of 200 MHz validate the effectiveness of the approach.
Hole drilling in crab and gastropod shells by Eledone cirrhosa (Lamarck, 1798)

Eledone cirrhosa readily feeds on crabs (e.g. Carcinus maenas) and gastropods (e.g. Nucella lapillus and Littorina littorea) in the laboratory. Penetration of the shells of these prey can be readily followed, with little or no disturbance, by suspending a microphone in the water and recording the sounds. The characteristic sound consists of a series of short bursts, resembling the noise of rasping, separated by quieter periods. A bore hole is formed through the shell of the prey with a morphology typical of the type of shell. In the gastropod this is located in a small area near the top of the shell, while in the crab nearly 60% were located in the carapace with 80% of these occuring in the lower left quadrant. Bore holes not in the carapace were located in the eyestalk or in the cuticle of the eye socket, in these cases the duration of the feeding sound was significantly shorter. The duration of the quiet periods are shortest at the initiation and at the completion of the bore hole. The central radula tooth can fit into the hole made in the shell of the crab and the characteristic pattern of wear indicates that it is subject to considerable abrasion when used. Chemical etching of the shell is involved in the formation of the bore hole. It is concluded that there is an alternation of periods of rasping by the radula and chemical etching during the making of the borehole.
Isotope encephalography in the management of acute herpesvirus encephalitis

Two patients with Herpesvirus hominis (herpes simplex) encephalitis were investigated by serial isotope encephalograms using technetium-99m pertechnetate. In the first case the diagnosis was made by brain biopsy, and by successful tissue culture, and was confirmed by a significant rise in antibody titre, but in the second the laboratory evidence was exclusively serological. Necrotizing encephalitis was presumed in both cases because the illness was grave and focal signs developed in conjunction with radiological and electroencephalographic evidence of circumscribed lesions of the hemisphere. The emergence of new lesions in the brain scan at a time of clinical remission was found to be a warning of impending relapse. Such lesions had to be distinguished from areas of increasing uptake of isotope due only to local change in vascular permeability. Decay of EEG activity together with clinical signs of focal abnormality over an area of isotope concentration indicated a necrotizing lesion. Cytosine arabinoside (cytarabine), an alternative to idoxuridine as an antiviral drug, was used in both cases. A third patient, suspected in life of having a degenerative encephalopathy, was found at necropsy to have necrotizing encephalitis. Herpes infection though probable was not confirmed. The most severe lesions were in the frontal and temporal lobes, which had shown increased uptake of technetium in the encephalogram performed six weeks before her death.
An improved modular multilevel converter with DC fault blocking capability

In contrast to the conventional half-bridge based MMC (HB-MMC), the full-bridge based MMC (FB-MMC) has the advantage of dc fault blocking capacity, but at the costs of increased power semiconductor devices and power losses. This paper proposes a hybrid modular multilevel converters (MMC) comprising of half half-bridge and half full-bridge sub-modules. The proposed topology takes the advantages of dc fault blocking capability of FB-MMC with less semiconductor devices and lower power losses than the FB-MMC. Comparative studies on power losses for different circuit configuration are conducted. Detailed pre-charge scheme for the proposed Hybrid MMC are designed and verified by simulations. Experiment results are provided to demonstrate the feasibility and validity of the proposed Hybrid MMC under normal operation and dc fault condition.
A systematic review of the relationship between patient mix and learning in work-based clinical settings. A BEME systematic review: BEME Guide No. 24

Background: Clinical workplace-based learning has been the means to becoming a medical professional for many years. The importance of an adequate patient mix, as defined by the number of patients and the types of medical problems, for an optimal learning process is based on educational theory and recognised by national and international accreditation standards. The relationship between patient mix and learning in work-based curricula as yet remains unclear. Aim: To review research addressing the relationship between patient mix and learning in work-based clinical settings. Method: The search was conducted across Medline, Embase, Web of Science, ERIC and the Cochrane Library from the start date of the database to July 2011. Original quantitative studies on the relationship between patient mix and learning for learners at any level of the formal medical training/career were included. Methodological quality was assessed and two reviewers using pre-specified forms extracted results. Results: A total of 10,420 studies were screened on title and abstract. Of these, 298 articles were included for full-text analysis, which resulted in the inclusion of 22 papers. The quality of the included studies, scored with the Medical Education Research Study Quality Instrument (MERSQI), ranged from 8.0 to 14.5 (of 18 points). A positive relationship was found between patient mix and self-reported outcomes evaluating the progress in competence as experienced by the trainee, such as self-confidence and comfort level. Patient mix was also found to correlate positively with self-reported outcomes evaluating the quality of the learning period, such as self-reported learning benefit, experienced effectiveness of the rotation, or the instructional quality. Variables, such as supervision and learning style, might mediate this relationship. A relationship between patient mix and formal assessment has never been demonstrated. Conclusion: Patient mix is positively related to self-reported learning outcome, most evidently the experienced quality of the learning programme.
Vascular resistance of central retinal and ophthalmic arteries in postmenopausal women after use of tibolone

ObjectiveThe aim of this study was to evaluate the effect of tibolone on vascular resistance of the central retinal and ophthalmic artery in postmenopausal women and to compare this effect with that of placebo using transorbital ultrasound with Doppler velocimetry. MethodsWe performed a prospective randomized, double-blinded, placebo-controlled study. A total of 100 healthy postmenopausal women (follicle-stimulating hormone, >40 IU/L) younger than 65 years were studied. The participants were randomly allocated to two groups: placebo (n = 50) and tibolone (2.5 mg; n = 50). Transorbital Doppler velocimetric ultrasound was performed before treatment and 80 days after. ResultsThe mean age was similar in both groups. Participants who received tibolone did not show any difference in pulsatility index, resistance index, and systole/diastole ratio of the central retinal and ophthalmic arteries after treatment. The same was observed in participants who received placebo. ConclusionsOur study demonstrates that tibolone administration to healthy postmenopausal women does not affect the resistance of small-caliber cerebral arteries.
Constrained Constant Modulus RLS-based Blind Adaptive Beamforming Algorithm for Smart Antennas

In this paper, we study the performance of blind adaptive beamforming algorithms for smart antennas in realistic environments. A constrained constant modulus (CCM) design criterion is described and used for deriving a recursive least squares (RLS) type optimization algorithm. Furthermore, two kinds of scenarios are considered in the paper for analyzing its performance. Simulations are performed to compare the performance of the proposed method to other well-known methods for blind adaptive beamforming. Results indicate that the proposed method has a significant faster convergence rate, better robustness to changeable environments and better tracking capability.
Acyclovir Induced Acute Kidney Injury In Acute Meningitis Patient: A Case Report Highlights the Concurrence Of AKI Risk Factors And The Neutropenic Effect Of Ticlopidine

Nephrotoxicity is one of the challenging side effects of acyclovir use in clinical practice. The Concomitant use of other nephrotoxic antibiotics, in addition to patient's risk factors, can trigger acyclovir induced acute kidney injury (AKI). We described a case of acute meningitis in 68 year old female patient with underlying history of ischemic heart disease managed by ticlopidine. The gram stain, culture and PCR of the CSF did not show any positive growth of bacterial infection or HSV. However, the negative CSF gram stain and culture caused a confusion of the diagnosis of bacterial meningitis with viral meningitis. The patient had AKI induced by the treatment with acyclovir for 16 consecutive days and possibly triggered by other AKI risk factors. Hemodialysis and hydration did not reverse the kidney function to normal. However, it was reversed to its normal status only after the discontinuation of acyclovir. The neutropenic effect of ticlopidine can be a risk to the patient that could lead to fatal infection. In this case report we reviewed the literature on the nephrotoxicity of acyclovir, the neutropenia of ticlopidine and a proposed role of granulocyte colony stimulating factor (GCSF).
An Ecological Analysis of Middle School Misbehavior Through Student and Teacher Perspectives

This study was designed to investigate how the classroom ecology (interactions among task systems) and program of action influence participants’ understandings of misbehavior in a middle school physical education setting. One teacher and 14 students participated in a 10-day basketball unit with 47- minute classes. Data included fieldnotes, stimulated recall using videotapes, and semi-structured teacher and student pre- and post-unit interviews. Data were first analyzed inductively by constant comparison (Strauss & Corbin, 1998) and then by using Doyle’s (1986) classroom ecology model to understand the inductively generated categories. Data trustworthiness involved prolonged engagement, member checks, and triangulation. Results indicated that the teacher’s weak managerial task system, coupled with vague and incomplete instructional tasks, interacted with a student social system grounded in various forms of talk as social tasks to support a social program of action. Both teacher and student actions jointly .
Alleviate Effects of Lanthanum on Stress Induced by cadmium on Carassius auratus

Impact on liver tissue of Carassius auratus by 0.5 mg/L -1 cadmium with additional 0.25, 0.5 and 1.0 mg/L -1 lanthanum was measured by ROS content, MDA content and Fourier Transform infrared spectrum analysis. The results showed 0.5 and 1.0 mg/L -1 lanthanum could alleviate cadmium stress by eliminate excessive ROS and MDA within 1-3 days, and 1.0 mg/L -1 lanthanum could decrease these two value to nearly normal level, showing the best effect. The Fourier transform infrared spectrum analysis showed under 0.5 mg/L -1 cadmium stress, protein structure composing was changed, the percent of alpha-Helix structure increased and the location of peaks included in Amide I regions shifted to lower wave numbers. Different lanthanum solutions, especially 1.0 mg/L -1 lanthanum could largely restore the protein structure disorder phenomena, which return shift peak location to normal direction and increased lower alpha-Helix structure percent. The influences of cadmium and lanthanum on lipid and nucleic metabolism were studied, the results showed lipid metabolism was vulnerable to cadmium stress, and both tested lanthanum solutions could recover the peak location shift and peak area increasing phenomena induced by 0.5 mg/L -1 cadmium stress, while no obviously influence was detected in nucleic metabolism under cadmium stress and lanthanum treatment conditions. The results showed FTIR was a sensitive method to study fish cadmium resistance physiology.
Multimodality Management of Vertebral Artery Injury Sustained During Cervical or Craniocervical Surgery

BACKGROUND: Iatrogenic vertebral artery (VA) injury is a rare but potentially devastating complication associated with cervical and craniocervical surgery. OBJECTIVE: To retrospectively evaluate treatment modalities and outcomes associated with iatrogenic VA injury. METHODS: Our institutional surgical database was queried for patients who underwent cervical or craniocervical surgery from January 1997 to August 2012. RESULTS: During this time period, 8213 patients underwent cervical or craniocervical surgery, and 17 (0.2%) cases of VA injury were identified. Eight (47%) of these injuries occurred during C1-2 instrumentation procedures. Primary microsurgical repair of the VA was performed in 5 patients. Other cases were managed by either surgical or endovascular VA occlusion. Of the 17 patients, 15 underwent immediate angiography, 9 of whom were ultimately treated by the use of endovascular techniques. CONCLUSION: VA injury is an uncommon complication of cervical and/or skull base surgery. Standardized management recommendations may help reduce complications associated with these rare but potentially devastating injuries. ABBREVIATIONS: ACDFP, anterior cervical discectomy with fusion and plating CTA, computed tomography angiography PICA, posterior inferior cerebellar artery POD, postoperative day SAH, subarachnoid hemorrhage VA, vertebral artery
Soy food intake and risk of gastric cancer

Abstract Epidemiological studies were inconsistent on the association between soy food intake and risk of gastric cancer (GC). This study aimed to determine the role of soy food intake in the development of GC. A systematic search was conducted in PubMed and Web of Science to identify all relevant studies. Study-specific relative risks (RRs) and 95% confidence intervals (CIs) were pooled using a random-effects model, and the dose–response relationship between soy food intake and GC risk was also assessed. Thirteen prospective studies were identified with a total of 517,106 participants and 5800 cases. Among 11 types of soy food, high intake of total soy food (the highest vs the lowest category: RR: 0.78, 95% CI: 0.62–0.98) and nonfermented soy food (RR: 0.63, 95% CI: 0.50–0.79) were inversely associated with GC risk, while high intake of miso soup was associated with the risk in male (RR: 1.17, 95% CI: 1.02–1.36). In dose–response meta-analysis, total soy food intake (0–150 g/day) showed no significant association with GC risk, while high intake of nonfermented soy food was inversely related, especially an intake of more than 100 g/day. In male, miso soup intake (1–5 cups/day) was significantly associated with GC risk. High intake of nonfermented soy food might reduce the risk of GC, while miso soup intake might increase the risk in male.
A single tryptic fragment of colicin E1 can form an ion channel: Stoichiometry confirms kinetics

The molecularity of the ion channel formed by peptide fragments of colicin has taken on particular significance since the length of the active peptide has been shown to be less than 90 amino acids and the lumen size at least 8 Å. Cell survival experiments show that killing by colicin obeys single‐hit statistics, and ion leakage rates from phospholipid vesicles are first order in colicin concentration. However, interpretation in molecular terms is generally complicated by the requirement of large numbers of colicin molecules per cell or vesicle.
Closely related species of birds differ more in body size when their ranges overlap—in warm, but not cool, climates

Differences in body size are widely thought to allow closely related species to coexist in sympatry, but body size also varies as an adaptive response to climate. Here, we use a sister lineage approach to test the prediction that body size differences between closely related species of birds worldwide are greater for species whose ranges are sympatric rather than allopatric. We further test if body size differences among sympatric versus allopatric species vary with geography, evolutionary distance, and environmental temperatures. We find greater differences in size among sympatric compared with allopatric lineages, but only in closely related species that live where mean annual temperatures are above 25°C. These size differences in warm environments declined with the evolutionary distance between sister lineages. In species living in cooler regions, closely related allopatric and sympatric species did not differ significantly in size, suggesting either that colder temperatures constrain the evolutionary divergence of size in sympatry, or that the biotic selective pressures favoring size differences in sympatry are weaker in colder environments. Our results are consistent with suggestions by Wallace, Darwin, and Dobzhansky that climatic selective pressures are more important in cooler environments (e.g., high elevations and latitudes) whereas biotic selective pressures dominate in warm environments (e.g., lowland tropics).
Quantum inspired high dimensional hyperparameter optimization of machine learning model

The hyper-parameter optimization of machine learning model is not a completely solved problem. The exquisite combination of artificial tuning and grid search may be a good choice in the area where the dimension of hyper-parameters is very low. But for high-dimensional hyper-parameter optimization problems, artificial tuning and grid search are obviously helpless. In this paper, we propose a quantum inspired hyper-parameter search method, which employs a quantum inspired evolutionary algorithm integrated with the traditional neural network (NN) training technique to evolve a NN subject to accuracy on test set as the objective. We evaluate the proposed method on MNIST dataset and compare it with random search algorithm. Experimental results demonstrate the superiority of our proposed method.
Anion binding to bovine erythrocyte superoxide dismutase. Evidence for multiple binding sites with qualitatively different properties.

Abstract The binding of azide, thiocyanate, cyanate, and cyanide to bovine erythrocyte superoxide dismutase has been studied by means of optical spectroscopy, electron paramagnetic resonance (EPR) spectroscopy, and nuclear magnetic relaxation dispersion (NMRD). The results show that there are at least four anion binding sites on the protein, and these are divided equally into two classes. One of these classes of binding sites strongly binds 2 moles of azide producing an altered EPR spectrum, no change in the NMRD, and only a minor change in the visible optical spectrum. These two binding sites are considered to be the Zn2+ ions of the protein. The other class of binding sites binds 2 moles of cyanide, lowering the NMRD to the diamagnetic level, and producing substantial changes in the optical and EPR spectra. These two binding sites are considered to be the 2 Cu2+ ions of the protein. Thiocyanate and cyanate appear to bind only to the Zn2+, having no effect on the NMRD and minor effects on the optical spectrum, although each ion produces a characteristic EPR spectrum. Addition of excess azide to the protein results in the appearance of an intense charge transfer band near 373 nm, produces minor changes in the 2-azide complex EPR spectrum and lowers the NMRD to the diamagnetic level. The presence of excess cyanide produces an absorption band at 530 nm and a unique EPR spectrum (Rotilio, G., Finazzi Agro, A., Calabrese, L., Bossa, F., Guerrieri, P., and Mandovi, B. (1971) Biochemistry, 10, 611). The data have been rationalized in terms of a model in which zinc and copper are relatively close to each other in the protein, perhaps existing in a ligand-bridged bimetal complex.