Miracle-dz/UniFAR-FTUs huggingface dataset:
B-hepatiitin kantajan raskaus

M aailmassa on noin 240 miljoonaa Bhepatiitin kantajaa, joista enemmistö asuu Aasiassa ja Saharan etelänpuoleisessa Afrikassa. Tartunta äidistä vastasyntyneeseen tai lapseen on edelleen tärkein tekijä infektion leviämisessä. Taudin kroonistuminen riippuu oleellisesti tartuntaiästä: jos tartunta on tapahtunut alle viiden vuoden ikäisenä, jää infektoituneista kantajiksi yli 90 %, kun taas aikuisena tartunnan saaneista ainoastaan alle 5 %:lla infektio kroonistuu. Kroonisen infek tion merkkinä seerumin HBsAg-näyte (B-hepatiitin pinta-antigeeni) on positiivinen, mutta HBeAgnäyte (B-hepatiittiviruksen e-anti geeni) voi olla positiivinen tai negatiivinen. Viruksen replikaatioaktiivisuus korreloi seerumin HBVDNA-pitoisuuteen. Suuri HBV-DNA-pitoisuus (yli 106 IU/ml) ja HBeAg-positiivisuus ovat merkki suuresta tartuttavuudesta. Vuosittainen kirroosin kehittymisen riski on HBeAg-positiivisilla potilailla 2–6 % ja HBeAg-negatiivisilla 8–10 %. Elinaikainen riski saada B-hepatiittiin liittyvä komplikaatio, kuten maksakirroosi, maksan vajaatoiminta tai maksa solu syöpä, on noin 15–40 %. Suomessa todettiin vuonna 2015 yhteensä 400 uutta THL:n tartuntatautirekisteriin ilmoitettua B-hepatiittitapausta, joista kroonisia oli 387. Kokonaismäärä lisääntyi 130 tapauksella (48 %), todennäköisesti maahanmuuton vuoksi. Suomessa on 21 viime vuoden aikana todettu yhteensä 20 akuuttia ja 111 krooniseksi luokiteltavaa B-hepatiittia 0–4-vuotiaiden ikäryhmässä. Vastaavana ajanjaksona todettiin 20–49-vuotiailla naisilla yhteensä 1 972 kroonista hepatiittia eli vajaat 100 tapausta vuodessa. B-hepatiitin hoidosta on julkaistu vuonna 2012 EASL:n ja Kanadan hoitosuositukset ja tänä vuonna AASLD:n sekä Asian-Pasific clinical practice -hoitosuositukset sekä asiantuntijasuositus B-hepatiitin hoidosta raskauden aikana (1,2,3,4,5). Suosituksissa on otettu kantaa raskaana olevien B-hepatiitin seulontaan, B-hepatiitin hoitoon raskauden aikana ja infektion äidistä lapseen tarttumisen ehkäisyyn.
On the use of 4:2 compressors for partial product reduction

The 4:2 compressor has transformed the standard frame of mind for counter based partial product reduction schemes by introducing the notion of horizontal data paths within stages of reduction. Since its inception by Weinberger in 1981, this concept has soared in popularity in many digital multiplication and multi-operand addition schemes. The application of 4:2 compressors has also been the focus of several studies promoting its use over booth receding schemes. This paper provides an in depth looks at the 4:2 compressor, and a novel layout scheme for optimal placement will be presented.
Optimized resource distribution for interactive TV applications

Though ubiquitous, the full potential of consumer electronic devices in the home, as content creators, remains underutilized due to the limited interaction between the consumers and the existing on-demand application and media services. Although services such as interactive television could change this, the geographic distribution of groups of consumers and the need for on-the-fly media processing that this entails, makes the efficient utilization of resources a complex optimization task requiring mechanisms to simultaneously allocate processing and network resources to groups of users. However, these technologies have not yet been developed, and brute force methods remain prohibitively complex. In order to overcome this problem, this paper proposes heuristic algorithms to both generate end-to-end delay bound multicast trees for individual groups of users and to co-locate multiple multicast trees, such that a minimum group quality metric can be satisfied. The performance of the proposed heuristic solution is evaluated in terms of the serving probability, i.e., the resource utilization efficiency, and computation time of the resource allocation decision making process. Simulation results show that improvements in the serving probability of up to 50%, in comparison with existing generic resource allocation schemes, and several orders of magnitude reduction of the computation time, in comparison to an optimal linear programming solution approach, can be achieved.
SiGe BiCMOS technology for communication products

SiGe BiCMOS technology is reviewed with focus on recent advances including the achievement of >200 GHz Ft and Fmax SiGe transistors, integration with generic 0.13 /spl mu/m CMOS, and the realization of low-cost nodes for the integration of wireless transceivers. Record-breaking wireless and wire-line circuit examples are also provided.
Development of Global Deterioration Scale Staging Algorithm

The Global Deterioration Scale (GDS) is a useful tool for staging dementia; each stage is described by spe-cific characteristics. However, one should not rely on the presence or absence of a single symptom in determining the stage. There is a need for a systematic computerized program to enable untrained doctors to easily assess dementia. This study aimed to generate an algorithm to help stage dementia.
Clinical Study on Huayu Pill Combined with Chemotherapeutic Regimes in Treating Epithelial Ovarian Cancer

Objective To observe clinical effects and side reactions of Huayu pill combined with TC (Paclitaxel+Carboplatin) chemotherapeutic regimes on treating epithelial ovarian cancer. Methods All 60 patients with the epithelial ovarian cancer were randomly divided into the treated group (Huayu pill combined with TC chemotherapeutic, n=30) and the control group (TC chemotherapeutic regimes, n=30). Results The effective rate of the treated group and the control group was 46.7% and 37.9% respectively. The objective response rate (CR+PR+SD) was 86.7% in the treated group, while this rate was 68.9% in the control group (P 0.05). Huayu pill can reduce the hypercoagulation of blood and side effects of chemical medicine and improve the quality of life. Conclusion Combined with TC chemotherapeutic regimes, Huayu pill can bring better clinical effects and relieve side effects of chemical medicine.
A Novel Algorithm for Key Frames Selection

The main objective of this study framework is to help the user to management the interesting video images from the huge storage device. The study can be divided into three main steps is listing as follows: shot boundary detection, key frame selection and evaluation method are designed by analyzing the video content. In this paper we proposed a novel algorithm for shot boundary detection. First, transform the RGB color model into LUV color model according our experimental results. The useful features of each frame are extracted from sequence images by the automatically computation of their color moment-preserving and matching 64-predefined bit planes in order to detect the shot boundary. The excellent shot boundary detection will result in the good key frames selection. Second, the key frame selection is proceed by applying the geometric invariant moments which successful be used in target tracing, pattern recognition, and facial recognition. In our experiments we used five test sequences that belong to five different program categories: movies, advertising, sport game, news, and commercial documentary. The experimental results showed that our method is feasible, effective, and is better than the former approaches.
La construction de l’identité des jeunes homosexuels au portugal

Cet article porte sur les significations individuelles, sociales et politiques de l’homosexualite dans un echantillon d’adolescents gays et d’adolescentes lesbiennes portugais. La methode de recueil de donnees est celle du focus groupe, avec un guide de discussion construit a partir des outils conceptuels du modele de McCarn et Fassinger, ceci afin d’evaluer l’adequation de ces concepts aux discours et aux representations personnelles et collectives : i) sur l’impact des experiences subjectives dans le developpement de la prise de conscience et de la differenciation homosexuelle, ii) sur la negociation de l’identite gay et lesbienne avec l’autrui significatif et iii) sur la contribution de la mobilisation politique et du coming out a une identite non discriminatoire. Les resultats contribuent a la connaissance des significations individuelles et groupales de l’homosexualite a l’adolescence et de leur influence sur la qualite du developpement psychologique des jeunes homosexuels. Enfin, quelques suggestions seront faites pour la mise en place d’une pratique de conseil efficace dans les ecoles pour cette population.
Two Fatalities Associated with Sibutramine

Sibutramine is an amphetamine derivative that has been prescribed as an antidepressant and appetite suppressant. It was voluntarily removed from the U.S. market in 2010 following a clinical trial that showed an increased risk of stroke and myocardial infarction. It has been detected as a clandestine additive in some over-the-counter weight loss and herbal remedies available on the Internet and in retail stores. We describe two fatalities involving the non-prescribed use of sibutramine by women using over-the-counter, herbal, weight loss supplements. Physicians need to be aware of inadvertent ingestion of sibutramine by patients who take herbal remedies for weight loss. Medical examiners and coroners may consider further investigation of sudden deaths in people who are taking herbal remedies for weight loss even with a history of heart disease. Since routine toxicology screens may not detect sibutramine, the toxicology laboratory should be informed when sibutramine is suspected.
Vertex Splitting in Isostatic Frameworks

On demontre que des divisions de sommet le long de 0, 1 ou 2 aretes d'une charpente de barres et de joints dans I'espace tridimensionnel respectent I'independance pour p resque toutes les positions du nouveau sommet. On demontre, en corollaire, que les divisions de sommet le long de 2 aretes d'une charpente dans I'espace tridimensionnel preservent la rigidite stati que pour presque toutes les positions du nouveau sommet. On applique cette technique a la rigidite generique des surfaces triangu lees dans I'espace tridimensionnel, incluant toutes les spheres et les plans projectifs. Des analogues sont enonces pour les espaces a n dimensions
Face tracking and recognition: from algorithm to implementation

This paper describes a system capable of realizing a face detection and tracking in video sequences. In developing this system, we have used a RBF neural network to locate and categorize faces of different dimensions. The face tracker can be applied to a video communication system which allows the users to move freely in front of the camera while communicating. The system works at several stages. At first, we extract useful parameters by a low-pass filtering to compress data and we compose our codebook vectors. Then, the RBF neural network realizes a face detection and tracking on a specific board.
Outcomes of Tetralogy of Fallot repair performed after three years of age

subject of debate, however, in general repair before 3 years of age has resulted in good myocardial performance. Late repair has led to prolonged QRS duration, ventricular dysfunction in terms of myocardial performance index (MPI) and tricuspid annular plane systolic excursion (TAPSE), as well as longer intensive care unit (ICU) stays. Objective To evaluate QRS duration, right ventricular function as measured by TAPSE, and ICU length of stay (LoS) after repair of TOF performed after three years of age. Methods This retrospective cohort study was performed in children and adults who underwent ToF repair, with a minimum follow-up of 6 months. The TAPSE and QRS duration were evaluated during follow-up and compared between children who had the operation before vs. 3 years of age or older using Mann Whitney U and Chi-square tests. Results We enrolled 52 subjects who underwent ToF repair from January 2007 to June 2013 (18 in the ≤3 years-old group and 34 in the >3 years-old group). Subjects’ age at the time of repair ranged from 7 months to 25 years, with follow-up data at 24-30 months after discharge. Abnormalities of the right ventricle and left ventricle MPI were not significantly different between the two groups. However, we observed significant differences between the ≤3 years and >3 years groups in median ICU LoS [2 (range 1-9) days vs. 1.5 (range 1-46) days, respectively; (P=0.016)] and median QRS durations [118 (range 78-140) ms vs. 136 (range 80-190) ms, respectively; (P=0.039)]. The age at the time of repair did not increase the risk of having abnormal TAPSE (RR 0.85; 95%CI 0.26 to 2.79; P=0.798). Conclusion Tetralogy of Fallot repair after 3 years of age appears to not increase ICU LoS or is associated with lower TAPSE, but it is associated with longer QRS duration. [Paediatr Indones. 2016;56:176-83. ].
Readings in Machine Learning

From the Publisher: The ability to learn is a fundamental characteristic of intelligent behavior. Consequently, machine learning has been a focus of artificial intelligence since the beginnings of AI in the 1950s. The 1980s saw tremendous growth in the field, and this growth promises to continue with valuable contributions to science, engineering, and business. Readings in Machine Learning collects the best of the published machine learning literature, including papers that address a wide range of learning tasks, and that introduce a variety of techniques for giving machines the ability to learn. The editors, in cooperation with a group of expert referees, have chosen important papers that empirically study, theoretically analyze, or psychologically justify machine learning algorithms. The papers are grouped into a dozen categories, each of which is introduced by the editors.
Biomimetic Scaffolds Loaded with Adipose-Derived Stem Cells and BMP-2 Induce Healing of Mandibular Defects

Objectives: Investigate the efficacy of biomimetic scaffolds, alone and in combination with osteogenic signaling factors and adipose-derived stem cells (ASCs), to heal a critical-sized segmental mandibular defect in a rat model. Study Design: Prospective study using an animal model. Methods: Adipose-derived stem cells were isolated and cultured from the inguinal fat of green fluorescent protein (GFP)-transgenic Lewis rats. Using 3D printing, biomimetic PLGA scaffolds were fabricated and impregnated with ASCs and/or bone morphogenic protein (BMP-2). Critical-sized 5-mm segmental mandibular defects were created in adult Lewis rats and implanted with 1) blank PLGA scaffolds, 2) PLGA scaffolds seeded with ASCs, 3) PLGA scaffolds with BMP, 4) PLGA scaffolds with BMP and ASCs. Animals were sacrificed at 12 weeks, and bone healing was evaluated using microCT analysis. Results: A total of 28 rats underwent creation of segmental mandibular defects with implantation of biomimetic scaffolds. MicroCT analysis demonstrated no bridging of the segmental bony defect in rats implanted with blank scaffolds (control). Rats implanted with scaffolds containing ASCs, BMP-2, and ASCs in combination with BMP-2 demonstrated healing of critical-sized segmental mandibular defects, as determined by microCT analysis. Conclusions: ASCs and BMP-2, alone and in combination, demonstrate the ability to heal critical sized mandibular defects in rats. This has implications for future translational research in oromandibular reconstruction.
Homo ludens : proeve eener bepaling van het spel-element der cultuur

In addition to his historical works, and his biographies, as his life was drawing to a close, Huizinga spent his time studying general cultural theories. Huizinga saw the instinct for play as a central element in human culture: 'In myth and ritual the great instinctive forces of civilized life have their origin: law and order, commerce and profit, craft and art, poetry, wisdom and science. All are rooted in the primeval soil of play. ' In Homo Ludens Huizinga attempts to show the impact of play on almost every aspect of culture, in other words how culture is shaped by play. The importance of this endeavor is that it identifies play as an independent phenomenon. Play for Huizinga has its own organizational forces, its own purposes and its own space.
Pathogenesis of mycosis fungoides and Sézary syndrome

Primary cutaneous T-cell lymphomas (CTCL) are a heterogeneous group of lymphoproliferative disorders derived from “skin-homing” lymphocytes CD4+. This phenomenon is also observed in the course of other chronic inflammatory processes in the skin, which results in significant diagnostic difficulties in CTCL, especially in the early stages of the disease. Recent studies indicate the pathogenetic complexity of CTCL. It is believed that one of the most important factors leading to the clonal proliferation of lymphocytes in the skin is its microenvironment. It has been proved that not only CLA (cutaneous leucocyte antigen) but also numerous chemokines, their receptors (CCR4, CCR10, CCL17, CCL27) and cytokines (IL-15, IL-16, IL-17, IL-21, IL-22) are involved in the process of skin infiltration. In this article we present PRACE POGLĄDOWE SŁOWA KLUCZOWE: chłoniaki pierwotnie skórne z komórek T, immunologia, genetyka, markery nowotworowe.
PSI and Psychoanalysis.

Dr. William B. Bean is in the midst of collecting data on the life and times of Major Walter Reed—of Yellow Fever fame. He would appreciate any information concerning original documentary material, letters, papers, or other primary source material related to Major Reed. Such information can be transmitted to the book review editor or directly to Dr. Bean at the University of Iowa, College of Medicine, Department of Medicine, Iowa City 52240. PSI is the term used to describe the alleged phenomena which formerly were categorized under a number of separate headings such as mental telepathy, thought transference, clairvoyance, extrasensory perception, etc. The author of this book believes that PSI is operative in explaining various "correspondences" or coincidences he frequently encounters in the practice of psychoanalysis. Examples of correspondences are: two patients report similar dreams closely related in time, the analyst and the patient dream similar dreams, either the patient
Management of primary thalamic low-grade glioma in pediatric patients: results of the multicenter treatment studies HIT-LGG 1996 and SIOP-LGG 2004.

Background Thalamic low-grade glioma (LGG) poses a special therapeutic challenge, as complete resection is often not possible. To determine the survival outcomes of mono- and bithalamic LGG, we analyzed a large cohort of pediatric patients. Methods From 1996 until 2012, 2618 patients were registered in the HIT-LGG 1996 and the SIOP-LGG 2004 studies. A total of 102 of these 2618 patients (3.9%) were diagnosed with a thalamic LGG with a median age at diagnosis of 8.0 years (range, 0.4-17.5 years); 87 patients (85%) had monothalamic and 15 patients (15%) had bithalamic LGG. Results Ninety patients received at least one surgical procedure. Thirty-one patients received radiotherapy and 24 patients received chemotherapy as a first-line, nonsurgical treatment indicated by radiological tumor progression or severe/progressive clinical symptoms. Patients with monothalamic tumors showed a 10-year overall survival (OS) rate of 91%, whereas patients with bithalamic tumors only reached 65% (P = .001). Bithalamic tumors more frequently showed diffuse histology than monothalamic tumors. Patients with diffuse astrocytoma had a lower 10-year OS (68%) than those with pilocytic astrocytoma (93%). The 10-year progression-free survival rate after the start of first nonsurgical treatment was 53% in the radiotherapy group and 34% in the chemotherapy group. Conclusions Thalamic glioma was manageable using a strategy that included surgery, observation, chemotherapy, and/or radiotherapy. Radiotherapy could be successfully deferred or obviated in a number of patients. Survival was high in among patients with monothalamic tumors. The worse prognosis associated with bithalamic tumors correlates with the higher rate of diffuse histology in this subgroup, precluding total or near-total resection.
Multipath Delay Characteristics on Line-of-Sight Microwave Radio System

Multipath properties on microwave line-of-sight links for the purpose of applying to microwave systems design are discussed. The theoretical analyses of the fading mechanism and the relation between multipath delay and radio duct parameters are carried out using the ray-optical method. Multipath delay have been measured with the frequency-sweep method and the three-frequency method on several paths in Japan since 1954. These paths are distributed in length from 20 km to 80 km, and include horizontal and slant paths. Through these theoretical and experimental analyses, a number of wave components in multipath propagation, the probability density function of multipath delay, the maximum delay and the relation between multipath delay and radio duct parameters are examined. The estimation method for path-length difference statistics, needed for evaluation of propagation distortion, is quantitatively given.
Role of Micro- and Mesosystems in Shaping an Adolescent

Adolescence is a vulnerable period in an individual’s life during which several physiological and psychological changes occur. Increasingly, across the globe, there is increasing incidence of mental health and behavioural problems documented, especially among the youth. The WHO states that mental health conditions and delinquent behaviours contribute significantly to the global disease burden. The transition from adolescence to adulthood is also marked by increasing manifestation of emotional and behavioural disorders with first episodes making their appearance in early adolescence. This review attempts to delve into the influence of microsystem and mesosystems as described by Bronfenbrenner on adolescent behaviours.
Alternativas de solución frente a la violencia escolar

El presente articulo de reflexion pretende invitar a los miembros de la comunidad educativa a realizar adecuadas meditaciones sobre el impacto de distintos tipos de violencia escolar y su repercusion en la sociedad; se toma como ejemplo el trabajo realizado en dos instituciones educativas en contextos rurales. De la misma forma, se presentan aqui diversas estrategias que permiten disminuir actos de violencia en las instituciones educativas, contribuyendo de esta manera a mejorar la convivencia entre los actores principales de estas comunidades
Commentary: NanoMEMS

NanoMEMS exploits the convergence between nanotechnology and microelectromechanical systems (MEMS) brought about by advances in the ability to fabricate nanometer-scale electronic and mechanical device structures. While the "Nano" aspect of this field is in its infancy, and is not expected to reach maturity until well into the 21st century, its "MEMS" aspect is a topic of much current and near-term impact in, for instance, inertial sensing, biomedicine, optical and RF/Wireless communications. In this context, we will begin this talk by discussing the fundamentals of NanoMEMS, in particular, as it relates to its most speculative and futuristic paradigms and applications, and then will focus on the RF/Wireless MEMS aspect, specifically in its role as enabler of ubiquitous wireless connectivity. We conclude by pointing out potential pitfalls to be encountered in its development, in particular, by addressing the subjects of stiction and pull-in in the contexts of varactors (Casimir effect) and switches.
Ethical Considerations concerning Screening for Chromosome Aneuploidy: A Response to a 2007 American College of Obstetricians and Gynecologists Practice Bulletin

Historically, maternal age 35 years or older at the time of delivery has been the marker to identify women with a statistically greater chance for having a child with a chromosome aneuploidy. This article will examine certain aspects of the recommendations made by the American College of Obstetricians and Gynecologists (ACOG) in 2007 to expand aneuploidy screening to all women before 20 weeks gestation. The article will focus on insights within the Catholic moral tradition that help to frame a reexamination of these recommendations.