Miracle-dz/UniFAR-FTUs huggingface dataset:
Diadococinesia labial em indivíduos adultos portadores e não portadores de doença de parkinson idiopática Labial diadochokinesia in adults with and without idiopathic parkinson's disease Diadochokinesia labial en adultos con y sin enfermedad de parkinson idiopática

Objective: characterize the differences between diadochokinesis lip values of speakers with and without Parkinson’s disease. Methods: it was performed a cross-sectional observational study in the period of October 2008 to July 2010. The subjects of the study group were patients with Parkinson’s disease periodically followed up by neurologists. Individuals invited to participate in the control group were the companions of patients, but also companions of patients of the Clinic of Speech. Participants underwent speech recording based on testing of labial diadochokinesia. We used the nonparametric statistical test for independent samples, Mann-Whitney test. Result: The study included 85 subjects. By comparing the case and control groups regarding labial diadochokinesia, it appears that there was a statistically signifi cant difference for the parameters of DDKcvp, and DDKjit DDKcvi. Conclusion: The results suggest a lower capacity of speakers with Parkinson’s disease to maintain a constant rate of CV combinations (/ pa /) and less ability to maintain a constant amplitude of the CV combinations (/ pa /) compared with noncarriers of Parkinson’s disease.
A Cross-Disciplinary Review of Blockchain Research Trends and Methodologies: Topic Modeling Approach

Given the increasing interest in blockchain technology, we present a large-scale cross-disciplinary literature analysis of research on the blockchain using topic modelling with the goal of identifying the major research trends, research methodologies, and fruitful areas for further research. In particular, the analysis focuses on abstracting out research trends from relevant terms and topics related to the research disciplines of Business, Computer Science, Economics, Social Sciences, Engineering, Healthcare, and Law. A total of 2,125 articles published between 2008 to up until early 2019 in academic journals and conferences were analyzed. Results of our analysis reveal that research is bipartite between practical and research domains, with academic research on blockchain not clearly aligning with organizational and social benefits. Also, we found – 1) few inter-disciplinary publications, and 2) a small number of studies that use surveys, experiments, and case studies as their research method. Our findings also reveal that research on Blockchain in the social sciences and law is still in the embryonic stage, thus making it essential to develop more direct research efforts for Blockchain to thrive in all research
An ensemble square root filter for the joint assimilation of surface soil moisture and leaf area index within the Land Data Assimilation System LDAS-Monde: application over the Euro-Mediterranean region

Abstract. This paper introduces an ensemble square root filter (EnSRF) in the context of jointly assimilating observations of surface soil moisture (SSM) and the leaf area index (LAI) in the Land Data Assimilation System LDAS-Monde. By ingesting those satellite-derived products, LDAS-Monde constrains the Interaction between Soil, Biosphere and Atmosphere (ISBA) land surface model (LSM), coupled with the CNRM (Centre National de Recherches Meteorologiques) version of the Total Runoff Integrating Pathways (CTRIP) model to improve the reanalysis of land surface variables (LSVs). To evaluate its ability to produce improved LSVs reanalyses, the EnSRF is compared with the simplified extended Kalman filter (SEKF), which has been well studied within the LDAS-Monde framework. The comparison is carried out over the Euro-Mediterranean region at a 0.25 ∘ spatial resolution between 2008 and 2017. Both data assimilation approaches provide a positive impact on SSM and LAI estimates with respect to the model alone, putting them closer to assimilated observations. The SEKF and the EnSRF have a similar behaviour for LAI showing performance levels that are influenced by the vegetation type. For SSM, EnSRF estimates tend to be closer to observations than SEKF values. The comparison between the two data assimilation approaches is also carried out on unobserved soil moisture in the other layers of soil. Unobserved control variables are updated in the EnSRF through covariances and correlations sampled from the ensemble linking them to observed control variables. In our context, a strong correlation between SSM and soil moisture in deeper soil layers is found, as expected, showing seasonal patterns that vary geographically. Moderate correlation and anti-correlations are also noticed between LAI and soil moisture, varying in space and time. Their absolute value, reaching their maximum in summer and their minimum in winter, tends to be larger for soil moisture in root-zone areas, showing that assimilating LAI can have an influence on soil moisture. Finally an independent evaluation of both assimilation approaches is conducted using satellite estimates of evapotranspiration (ET) and gross primary production (GPP) as well as measures of river discharges from gauging stations. The EnSRF shows a systematic albeit moderate improvement of root mean square differences (RMSDs) and correlations for ET and GPP products, but its main improvement is observed on river discharges with a high positive impact on Nash–Sutcliffe efficiency scores. Compared to the EnSRF, the SEKF displays a more contrasting performance.
Fractality: a key to global citizenship

This paper develops the notion of fractality as a concept-of-choice upon which to build a way of knowing or paradigm that may better resonate with the complexities of the human experience of the 21 Century and thus lead to responses different from the winner-loser, usand-them, for-us-or-against-us polarisation. Fractality is a concept from Mathematics and Complexity Theory; it being an entity that has self-similarity at many scales of focus. It is the scientific expression of the Golden Rule. At different scales of focus, the human fractal can be described as an individual human being, his or her family, the population of his or her town or city, the population of his or her State, Province or Department, the population of his or her nation or the global population in its entirety within the universe. The concept of a fractal makes this complexity manageable to comprehend: because understanding the fractal at one scale of focus is to understand the fractal at all scales of focus, though not with the same degree of precision. This perception of self as self, self as family, self as township, self as national population and self as global population has significant implications for how we choose to govern, decide and act as humans in relation to each other and to our environments, particularly from the perspectives of what it means to be just, equitable, ethical and moral. This paper presents a way of knowing developed from fractality and explores some of its implications for how we can decide what is just, equitable, ethical and moral not only for ourselves as humans but for the environment as well. The knowing-living dynamic Our ways of knowing and ways of doing things in the world are in a dynamic relationship, each affecting the other. Our preferred, and often currently successful, ways of knowing inform what is correct, appropriate and acceptable decision-making and action-taking in the world. For example, among Australian Aborigines, it is not appropriate to kill a particular animal species if that species is one’s totem − it is known that there is a shared spiritual connection between the knower and that species. Similarly, among scientists, one better describes reality by carrying out experiments to determine what reality isn’t − it is known that reality is too vast to determine what it is specifically; better to determine specifically what it isn’t and thus gradually narrow down the possibilities.
A Tablet-Based Memory Enhancement Application for Older Users: Design Approach

This paper provides a case study of the design process undertaken in producing a mobile tablet memory assistant solution which was intended for older adults (>65yo) living with early stage memory loss. We adopted an overall design framework consistent with “living laboratory” methodology, for which the associated design principles are: cocreation, multi-stakeholder participation, active user involvement, real-life setting, and multi-method approach. We describe here the detailed steps and provide examples of the application design decisions and outcomes, through successive stages of its evolution. Results of the various user engagements which informed our design choices and for validation of the artefact are presented.
PARALISIA CEREBRAL: causas e prevalências título Cerebral palsy: causes and prevalences

INTRODUCTION: Cerebral Palsy (CP) is a common cause of physical disability and it’s defined as a non progressive group of developmental, movement and posture disorders. Studies conducted in countries such as Australia, Sweden, United Kingdom and United States verified cerebral palsy taxes of 2.0 to 2.5 per 1000 childbirths. In developing countries the incidence
Examination of Single Wavelet-Based Features of EHG Signals for Preterm Birth Classification

In this study, wavelet-based features of electrohysterogram (EHG) quantifying the electrical activity of uterine muscles are applied for preterm birth classification. EHG has been shown to provide useful information for uterine contraction that leads to the anticipation of delivery. A waveletbased feature referred to as ∆l in this study is determined from a difference between the logarithms of variances of detail coefficients of EHG data corresponding to two consecutive levels, i.e., l and l + 1. Performance on preterm birth classifications using single wavelet-based features of EHG data is examined. A simple thresholding technique is applied for preterm birth classifications. The leave-one-out cross validation is used to validate the performance on preterm birth classifications. From the computational results, it is shown that the wavelet-based features of EHG can provide a reasonable performance on preterm birth classification with the accuracy, the sensitivity and the specificity of 0.7099, 0.6842 and 0.7133, respectively.
Analytical Review of Methods for Identifying Emotions in Text Data ∗

The sentiment analysis of text is one of the important tasks in the ﬁeld of natural language processing. It is used in diﬀerent areas. Despite the variety of existing methods, the systems of sentiment analysis of Russian-language texts give low accuracy compared to English-language ones. The article discusses basic methods for identifying emotions in text data and methods of text vectorization. The existing achievements in the ﬁeld of computer sentiment analysis are analyzed. At the moment, there are many unsolved problems in the ﬁeld of automatic sentiment analysis
Toxicity of Cholantraniliprole against Different Developmental Stages of the Cotton Leafworm under Laboratory Conditions

Spodoptera littoralis management has been counted on the application of the synthetic chemical pesticides, but becauseof insecticides resistant problems in the cotton leafworm, the competence of these chemical have been reduced. So, newinsecticides with different action could solve this problem. In this study, the activity of a new insecticide,chlorantraniliprole (Coragen® 20%SC), was evaluated against different stages of S. littoralis. For egg stage of S. littoralis,two different ages, < 24 h and 24-48 h were used and dipped in serial concentrations of chlorantraniliprole. The resultpresented that the young eggs were more sensitive than the old one with LC50 value of 126.6 mg/l in case in the youngeggs while it was 144.81 mg/l in the old one. In addition, the larvae of 2nd instar were exhibited a high susceptibility tochlorantraniliprole after 96 hrs. In contrast, when pupae were dipped in chlorantraniliprole different concentrations, theresult showed no significant pupal mortality (20%) in the lower concentration (200-800 ppm), while the highestconcentration (800 mg/l) showed 43.3% mortality. The letant effect of chlorantraniliprole at LC25 (0.036 mg/l) on 2ndinstar showed that the developmental time of larval and pupal stages has been prolonged and the percentage ofhatchability was reduced as contrasted to untreated larvae. The present results propose that Coragen® could be apotentially effective and likely to be an alternative insecticide that can be used for S. littoralis management in Egypt.
THE DEVELOPMENT OF NEUROINFLAMMATORY PROCESSES IN RATS IN EARLY POSTNATAL ONTOGENESIS AFTER PRENATAL HYPERHOMOCYSTEINEMIA

THE DEVELOPMENT OF NEUROINFLAMMATORY PROCESSES IN RATS IN EARLY POSTNATAL ONTOGENESIS AFTER PRENATAL HYPERHOMOCYSTEINEMIA A.D. Shcherbitskaia1, 2, D.S. Vasilev1, N.L. Tumanova1, Ju.P. Milyutina2, I.V. Zalozniaia2, A.V. Arutjunyan2 1 I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of Sciences, Saint Petersburg, Russia; 2 The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott, Saint Petersburg, Russia
How to Develop a GDPR-Compliant Blockchain Solution for Cross-Organizational Workflow Management: Evidence from the German Asylum Procedure

Blockchain technology has the potential to resolve trust concerns in cross-organizational workflows and to reduce reliance on paper-based documents as trust anchors. Although these prospects are real, so is regulatory uncertainty. In particular, the reconciliation of blockchain with Europe’s General Data Protection Regulation (GDPR) is proving to be a significant challenge. We tackled this challenge with the German Federal Office for Migration and Refugees. Here, we explain how we used Action Research to guide the Federal Office in creating a GDPR-compliant blockchain solution for the German asylum procedure. Moreover, we explain the architecture of the Federal Office’s solution and present two design principles for developing GDPRcompliant blockchain solutions for crossorganizational workflow management.
POWER SYSTEM STABILIZER DESIGN USING NOTCH-FILTER – BARKA II (OMAN) - CASE STUDY

The use of power system stabilizers (PSSs) to damp power system swing mode oscillations is of extreme practical importance. This manuscript presents an approach to the stabilization of a single machine infinite bus system (SMIB). The proposed control is based on the notch-filter approach to cancel the poles near to the imaginary axes. The approach is based on the root locus method. Application to Barka II power station connected to the main interconnected system of Oman is presented. The peak load at summer is considered as the system is near to instability. The Barka SMIB is modeled as a fourth order non-linear system. A linearized model is then obtained using MATLAB/Simulink. The simulation results validate the proposed design for the PSS.
Beyond genetic stability of mesenchymal stromal cells

Mesenchymal stromal cells (MSCs) have been used in the clinic for more than a decade. However, this rapidly emerging area of research (352 clinical trials registered at ClinicalTrials.gov) is associated with much debate and controversy. A major issue is the safety and risk of transformation of MSCs during ex vivo expansion. Previous articles (1,2), now retracted (3,4), or analyses (5) reported the transformation or risk of transformation of MSCs from different sources during expansion. Although such transformation is likely a rare event (6,7), some genetic abnormalities, mainly aneuploidy, can appear during culture but are not related to the transformation per se (8). Consequently, from a regulatory point of view, we need to develop processes avoiding such transformation that use relevant controls to avoid the risk of transformation. A recent review, following a meeting of the European Medicines Agency in London to ensure the safety of MSC production, at least in pre-clinical settings, determined that cytogenetic abnormalities should be assessed (9). In this issue of Cytotherapy, three teams report on the genetic stability of ex vivo-expanded human MSCs. MSCs used in these studies came from three different sources: two from adult tissue [bonemarrow (BMMSCs) (10) and adipose tissue (ASCs) (11)] and one from a fetal source [chorionic villi (CV MSCs) (12)]. The culture processes differed. BMMSCswere expanded in a bioreactor (Quantum Cell Expansion System; Terumo BCT, Lakewood, CO, USA), and ASCs and CV MSCs were expanded in flasks. The media were similar, including fetal bovine serum, with the addition of conditioned medium for CV MSCs. Finally, a wide range of techniques were used to assess genetic stability, including conventional karyotyping,
Theoretical study of a self-sustained CMOS-integrated nano-oscillator

Over the last ten years, the progress of Nanoelectromechanical systems (NEMS) fabrication has opened new possibilities for the use of NEMS as high-performance, low-cost, compact sensors [1]. In NEMS resonators-based sensors, the resonant frequency depends upon the physical parameter to be measured [2]. To track dynamically the time-varying resonant frequency of the NEMS, one approach consists in embedding the NEMS in a self-oscillating loop so that it oscillates at its resonant frequency. The resonator chosen in this study uses electrostatic actuation and capacitive detection. This has the advantage of having a relatively simple implementation and good transduction efficiency. Furthermore, this actuation/detection scheme makes possible the monolithical integration of the NEMS resonator with a dedicated CMOS circuit. Co-integrated sensors have higher signalto-noise ratios since parasitic capacitances are drastically reduced. Examples of cointegrated NEMS resonators are presented in [3-5]. The main contribution of this work is the design of a NEMS/CMOS oscillator (NEMS as resonant element, CMOS circuit as sustaining amplifier) with a very simple amplifying circuit based on a single active transistor. The design of the electronics and the oscillator steady-state response are theoretically studied. The micro/nanomechanical resonator is described in section 2, the oscillation conditions and the CMOS sustaining amplifier are respectively analyzed in sections 3 and 4. Finally, the steady-state regime of the oscillator is determined by using a describing function method in section 5.
Minimally Invasive Plate Osteosynthesis (MIPO) for Treatment of Comminuted Mid-Distal Third Humeral Shaft Fractures through the Anterior Approach

This study was conducted to evaluate the results of management of comminuted fractures of the mid-distal third shaft of the humerus with indirect reduction and internal fixation with plate and screws through minimally invasive technique using the anterior approach. Twenty-three comminuted fractures of the mid-distal third humeral shaft in 23 adult patients were managed using the minimally invasive plate osteosynthesis.
Evaluating Chondroitin Sulfate and Dermatan Sulfate Expression in Glial Scar to Determine Appropriate Intervention Time in Rats

Introduction: The proteoglycans of the extracellular matrix increases in the glial scar during spinal cord injury and significantly affects the inhibition of axonal regeneration. Methods: The results of injury therapies are limited due to the lack of identifying a timely therapeutic intervention. The present study aimed to investigate the glial scar Chondroitin Sulfate (CS) and Dermatan Sulfate (DS) levels at different post-injury times to determine the appropriate time for therapeutic intervention. Results: By this experimental study, 72 Wistar rats were randomly divided into 12 groups, as follows: control, sham, injured animals at 1, 2, 4, and 8 days, as well as 2, 4, 8, 12, 16, and 20 weeks post-injury. The animals in the injured groups were contused in the T10 segment of the spinal cord. The motor function of animals was assessed using the Basso, Beattie, and Bresnahan (BBB) test. Besides, the histological assessment was performed using Luxol Fast Blue and Bielshovisky Staining. The CS and DS levels of lesions were measured using the Enzyme-Linked Immunosorbent Assay (ELISA) method. Conclusion: The motor function assessment indicated a relative recovery over time. Histological results confirmed some regeneration in the injury site at 20 weeks post-injury. The ELISA results demonstrated a much higher level of DS than that of CS in the glial scar. Considering high levels of DS, compared to CS in the glial scar and its reduction from second weeks after SCI onwards, the second week after SCI seems to be the best time for therapeutic interventions in terms of scar permeability.
Dynamic Modelling of an Orientable Solar Panel System as a 2-DOF Manipulator

This manuscript was sent on January 24, 2019 and accepted on June 26, 2019. This work was supported by Research Affairs Division (Vicerrectoría de Investigaciones) of Universidad del Atlántico (Puerto Colombia, Colombia). J. Roldán-Mckinley works currently in the Mechanical Engineering Program (DIMER research group) at Universidad del Atlántico (Puerto Colombia, Colombia) (e-mail: javierroldan@mail.uniatlantico.edu.co). A. Fernández-Pizarro is a Mechanical Engineer from Universidad del Atlántico (Puerto Colombia, Colombia). He works as a Maintenance Engineer at Tubos 360 Company (Caracolí, Colombia) (e-mail: andres.fernandez@t360.com, affernandez@mail.uniatlantico.edu.co). J. Beltrán-González is a Mechanical Engineer from Universidad del Atlántico (Puerto Colombia, Colombia). He works as an Operations Engineer at Navarro Tovar SAS Company (Barranquilla, Colombia) (e-mail: operaciones@navarrotovar.com.co, jabeltran@mail.uniatlantico.edu.co). orientable. Los resultados mostraron concordancia para ambos
Factors influencing off-take rates of smallholder sheep farming systems in the Western Cape Provinve of South Africa

The purpose of this study was to determine off-take rates in smallholder sheep farming systems in the Western Cape province of South Africa. A purposeful sampling technique was used where smallholder farmers were selected based on certain criteria. The criterion set out was that farmers must own between five and 100 sheep. Interviews were conducted with 72 smallholder farmers in three districts, namely the West Coast, Karoo and Eden. General information on the socio-economic status of the farmers was obtained through semi-structured questionnaires. The main sources of income for the Karoo farmers was livestock (46%) and crops for Eden (32%). Farmers in the West Coast area mostly relied on salaries (43%), thus off-farm income. The Karoo district sold a higher average number of lambs per year (41 ± 8.8), with West Coast and Eden selling the same average number of lambs per year at 7 ± 2.2 and 7 ± 2.6 respectively. Overall, the income derived from livestock is low and not economically sustainable. Therefore, different strategies (such as access to market, financial assistance, improved animal nutrition and health management, as well as sound breeding plans) should be employed to assist smallholder livestock farmers to increase off-take rates.