Miracle-dz/UniFAR-FTUs huggingface dataset:
SFCD 1 ) Perioperative care in digestive surgery . Guidelines of the French society of digestive surgery ( SFCD )

a Service de chirurgie digestive et générale, hôpital C. Huriez, CHRU de Lille, place de Verdun, 59037 Lille, France b Service de chirurgie digestive, hôpital Lariboisière, Paris, France c Service de chirurgie générale, digestive et oncologique, hôpital A. Paré, Boulogne, France d Service de chirurgie digestive, hôpital Saint-André, CHU de Bordeaux, France e Service de chirurgie générale et digestive et de transplantation hépatique, hôpital de la Croix-Rousse, CHU de Lyon, France f Service de chirurgie générale et digestive, hôpital Hôtel-Dieu, CHU de Clermont-Ferrand, France
Study of goat milk and goat milk yogurt to decrease parasitemia index on malaria-infected mice

Malaria is an infectious disease caused by the Plasmodium sp. parasite. In 2017, malaria has reached 219 million cases. The decline of parasitemia index indicates a lower degree of infection in malaria patients. Goat milk and goat milk yogurt as immunomodulators have the potential to reduce parasitemia index. This study was aimed to determine the effect of goat milk and goat milk yogurt on the index of parasitemia in malaria-infected mice. This research was a true experimental study with a post-test only group design. A total of thirty-five female Balb/c mice was divided into the following groups: a (negative control group), b (malaria), c (malaria, Dihydroartemisinin/piperaquine (DHP) drug), d (malaria, goat milk), e (malaria, goat milk, DHP), f (malaria, goat milk yogurt), and g (malaria, goat milk yogurt, DHP). Inoculation dose of Plasmodium was 107 /0.2 mL. The intervention was studied for 24 days. Parasitemia index data was collected on the seventh day post-inoculation. The dose of goat milk and goat milk yogurt given was 0.5 mL/20 g BW. Data were analyzed using Kruskal-Wallis with Mann-Whitney post-hoc test. The results showed a significant decrease in the parasitemia index (p<0.05). The mean parasitemia index in each group were: 0% (a); 13.9% (b); 0.60% (c); 4.68% (d); 3.74% (e); 3.66% (f); 0.82% (g). The group that exhibited effective reduction of parasitemia index were group c and g. Goat milk yogurt (f) was more effective in decreasing the parasitemia index than goat milk (d). Giving goat milk yogurt can be considered an additional therapy for the treatment of malaria.
Critical role of the transcription factors IRF 1 and BATF in preparing the chromatin landscape during Type 1 regulatory cell differentiation

Type 1 regulatory T (Tr1) cells are induced by interleukin-27 (IL-27) and have critical roles in the control of autoimmunity and resolution of inflammation. Here, we show that the transcription Corresponding author: Vijay Kuchroo (vkuchroo@evergrande.hms.harvard.edu). Accession codes GSE92994, GSE92940 COMPETING FINANCIAL INTERESTS The authors declare no competing financial interests. AUHTOR CONTRIBUTIONS KK planned, performed and analyzed all biological experiments and wrote the manuscript. ERM designed and actuated computational analyses for RNA-seq/ATAC-seq, contributed to interpretation of the results and writing of the manuscript. MP prepared ATAC-seq libraries, coordinated sequencing with the NYUMC genomics core, contributed to interpretation of the results and general discussion. AM, NY, XC, AW and NC contributed to computational analysis. IW prepared RNA-seq libraries and coordinated sequencing. AA provided reagents and advice. AR developed and undertook transcriptional analysis of IL-27 induced Tr1 cells. RB contributed to computational analysis, interpretation of the results and writing of the manuscript. DL advised and provided insight into the analysis of ATAC-seq and RNA-seq analysis. VKK supervised the study and wrote the manuscript. HHS Public Access Author manuscript Nat Immunol. Author manuscript; available in PMC 2018 April 16. Published in final edited form as: Nat Immunol. 2017 April ; 18(4): 412–421. doi:10.1038/ni.3683. A uhor M anscript
Dynamic-coupling analyses of cells localization by the negative dielectrophoresis

Negative dielectrophoresis is widely used in cell localization for long-term observations such as the impedance analysis, in vivo drug screening, and cell patterns. However, the coupling effect of AC electrokinetics, including negative dielectrophoresis, AC electroosmosis, and electrothermal flow is still unclear. This work investigated cell localization based on the dynamic-coupling of dielectrophoresis, AC electroosmosis, and electrothermal flow. A two-dimensional finite element model that consisted of interdigitated array electrodes was established. The effects of system parameters on the capture efficiency were investigated, when the medium conductivity was in the range of 0.001–1 S/m. The selection of the medium conductivity is suggested to be the first step of the experiment design. Then, the choice of AC frequency and AC amplitude requires balancing the effects of transmembrane potential and temperature rise on cell viability. Besides, particular electrode spacing is evidenced to be only efficient for a specific cell diameter. Thus, the electrode spacing of the microfluidic chip needs to be optimized according to the cell's diameter.
Ultrasonic shears and bipolar vessel-sealing system for three-port laparoscopic ovariohysterectomy in dogs

In the current experimental study, two different instruments were compared for prophylactic hemostasis during a 3-port technique of laparoscopic ovariohysterectomy (OVH) in bitches. Moreover, the need for port enlargement for specimen retrieval using 5mm or 10mm trocartes, technical difficulties and complications were assessed. Ultrasonic energy and a vascular sealing system were tested. Duration of surgery, patient weight and diameter of the uterine arteries and veins were compared among the groups. Fifteen dogs randomly divided into three groups (GI, GII, GIII) were submitted to ovariohysterectomy with hemostasis from the use of ultrasonic scalpel or vascular sealing equipment. In GI and GII the LigaSure TM impedance-controlled bipolar vessel-sealing device was used, differing in the size of trocartes used between groups, and in GIII Autosonix TM was used. Patients' weight, duration of surgery, technical difficulties and complications were compared among the groups. Statistical analysis showed no difference between the data analyzed among the groups. In conclusion, both methods of hemostasis were effective for 3-port total laparoscopic ovariohysterectomy in bitches. However, 5mm trocartes were not adequate for retrieval of the uterus and ovaries without need for enlargement of the port incision.
The impact of dietary magnesium restriction on magnesiotropic and calciotropic genes

Background. Magnesium (Mg) is an essential electrolyte with important physiological functions. Consequently, hypomagnesaemia, an electrolyte disorder frequently diagnosed in critically ill patients, can have life-threatening consequences. The kidney plays a central role in the regulation of the Mg balance. The present study investigated the molecular consequences of dietary Mg restriction on renal Mg transporters. Methods. Two groups of 10 mice were fed a Mg-deficient diet or a Mg-enriched diet for 2 weeks. Serum and urine electrolyte concentrations were assayed. Next, renal mRNA expression levels of Mg-related genes were measured to determine their sensitivity to the dietary Mg content. Subsequently, parvalbumin (PV) and the thiazide-sensitive Na-Cl cotransporter (NCC), both co-expressed in the distal convoluted tubule (DCT) with TRPM6, were further analysed at the protein level using immunoblotting and immunohistochemistry. Results. Serum and urine electrolyte measurements revealed that dietary Mg restriction resulted in significant reduction of serum Mg and Ca levels, and that the urinary excretion of these ions was also markedly reduced, while phosphate (Pi) excretion was significantly increased. In addition, the serum FGF23 level was markedly increased, whereas Pi was not significantly changed in the Mg-restricted mouse group. The renal abundance of hepatocyte nuclear factor 1 homeobox B (HNF1B) and the epithelial Mg channel TRPM6 were increased in response to dietary Mg restriction, whereas other magnesiotropic transporters were not affected. PV abundance was upregulated, while NCC was significantly downregulated. Furthermore, the expression levels of the epithelial Ca channel TRPV5 and calbindin-D28K were markedly reduced in the low Mg group. Conclusions. Our data indicate an essential adaptive role for DCT during hypomagnesaemia since TRPM6, HNF1B, PV and NCC expression levels were adjusted. Moreover, hypomagnesaemia resulted in severe changes in Ca and Pi reabsorption and expression levels of calciotropic proteins.
The impact of firewall on TCP and UDP throughput in an openflow software defined network

Software Defined Networking (SDN) is an emerging networking paradigm that provides more flexibility and adaptability in terms of network definition and control. However, SDN is a logically centralized technology. Therefor the control plane (i.e. controller) scalability in SDN in particular, is also one of the problems that needs further focus. OpenFlow is one of the protocol standards in SDN, which allow the separation of the controller from the forwarding plane. The control plane has an SDN embedded firewall and is able to enforce and monitor the network activity. This firewall can be used to control the throughput. However, it may affect SDN performance. In this paper, throughput will be used as a performance metric to evaluate and assess the firewall impact on two protocols; Transmission Control Protocol (TCP) and User Datagram Protocol (UDP) that passes through the forwarding planes. The evaluations have been verified through simulating the SDN OpenFlow network using MININET. The results show that an implementation of firewall module in SDN creates a significant 36% average drop for TCP and 87% average drop for UDP in the bandwidth which eventually affect the quality of the network and applications.
Mapping of predictors of the disengagement of the descending inhibitory pain modulation system in fibromyalgia: an exploratory study

Background: The main symptoms of fibromyalgia comprise diffuse pain, disability, depressive symptoms, catastrophizing, sleep disruption and fatigue, associated with dysfunction of the descending pain-modulating system (DPMS). Objectives: We aimed to identify patterns of main symptoms of fibromyalgia and neuroplasticity biomarkers (i.e. brain-derived neurotrophic factor (BDNF) and S100B protein) in non-responders to the conditioned pain modulation task (CPM-task) induced by immersion of hand in cold water (0–1°C). Furthermore, we evaluated if these patterns predict responsiveness to CPM-task. Methods: This cross-sectional study included 117 women with fibromyalgia ((n = 60) non-responders and (n = 57) responders), with age ranging from 30 to 65 years old. We analysed changes in numerical pain scale (NPS-10) during the CPM-task using a standardized protocol. Results: A hierarchical multivariate logistic regression analysis was used to construct a propensity score-adjusted index to identify non-responders compared to responders to CPM-task. The following variables were retained in the models: analgesic use four or more times per week, heat pain threshold (HPT), poor sleep quality, pain catastrophizing, serum levels of BDNF, number of psychiatric diagnoses and the impact of symptoms of fibromyalgia on quality of life. Receiver operator characteristics (ROC) analysis showed non-responders can be discriminated from responders by a composite index of more frequent symptoms of fibromyalgia and neuroplasticity markers (area under the curve (AUC) = 0.83, sensitivity = 100% and specificity = 98%). Conclusion: Patterns of fibromyalgia symptoms and neuroplasticity markers may be helpful to predict responsiveness to the CPM-task which might help personalize treatment and thereby contribute to the care of patients with fibromyalgia.
COHOMOLOGY THEORIES ON LOCALLY CONFORMAL SYMPLECTIC MANIFOLDS

In this note we introduce primitive cohomology groups of locally conformal symplectic manifolds (M2n, ω, θ). We study the relation between the primitive cohomology groups and the Lichnerowicz-Novikov cohomology groups of (M2n, ω, θ), using and extending the technique of spectral sequences developed by Di Pietro and Vinogradov for symplectic manifolds. We discuss related results by many peoples, e.g. Bouche, Lychagin, Rumin, Tseng-Yau, in light of our spectral sequences. We calculate the primitive cohomology groups of a (2n+2)-dimensional locally conformal symplectic nilmanifold as well as those of a l.c. s. solvmanifold. We show that the l.c. s. solvmanifold is a mapping torus of a contactomorphism, which is not isotopic to the identity.
Sequential Scene parsing: Semantic Scene Approximation using Temporal and Physics Based Reasoning

A consistent scene approximation is essential to a performance of a robotic task that involves object manipulation with random poses. Although many computer vision techniques exist for segmenting and computing poses of the objects in scene [1, 2], these methods still generates inaccurate pose estimates when high amount of occlusions present in the scene. Additionally, since most techniques do not use previous scene results for constructing their current estimate, they can not generate a scene estimate that is stable over time. Building a time-conscious scene hypothesis requires an ability to extract new parameters that determine the time relationship between each scene. In this thesis, we propose an extension of the sequential scene parsing framework by Hager and Wegbreit [3] for constructing a physically consistent scene from RGB-D data received in a discrete-time series. In contrast to the original system, which was limited to geometry-based primitives scene estimate, we utilize semantic segmentation and object pose estimate using an RANSAC-based approach. This framework derives those data into scene components that incorporate collision consistencies, pose data ii
Making Ours Mine: Increasing Consumer Acceptance of Access-Based PSS through Temporary Product Customisation

Access-based product-service systems (AB-PSS) have the potential to lower environmental impacts. Currently, a lack of consumer acceptance and, consequently, low adoption levels of AB-PSS are challenges preventing the realisation of their sustainability potential. This study proposes temporary product customisation to lower barriers for the acceptance of AB-PSS. We investigated whether customisation through modifying the appearance of an easily changeable attribute of a typical product, and thereby changing the product personality, could improve consumer acceptance while limiting the impact on sustainability. To explore this, a 3 × 1 between-group design experiment was conducted with consumers who are familiar with offerings similar to the AB-PSS we tested. The results indicate that respondents have a strong preference, as is widely recognised, for typical products in an AB-PSS. Infusing meaning and intangible value into accessed products through customisation can simultaneously lead to wider acceptance in the market and individual consumers’ satisfaction. Our findings confirm that consumer acceptance increases if a product fulfils intangible needs along with functionality needs. The results can be used to think about new ways in which product design can enhance the diffusion of AB-PSS in the consumer market.
UvA-DARE ( Digital Academic Repository ) Shifting landscapes of immigrant entrepreneurship

Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: http://uba.uva. nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.
AL / EQ-TP-97-3100 SYNTHETIC CHEMICALS WITH POTENTIAL FOR NATURAL ATTENUATION POSTPRINT ( Code 20 )

Natural attenuation of petroleum hydrocarbons is predictable and self-sustaining because bacteria able to use the contaminants as growth substrates are widely distributed. In contrast, bacteria able to grow at the expense of chlorinated aliphatic compounds are less common and the natural attenuation of such compounds is, therefore, less predictable. The purpose of this paper is to describe examples of other synthetic organic compounds that are known to be biodegradable and have the potential for natural attenuation in the field.
Visual Outcome of Cataract Surgery Complications Repair at a Cataract Training Centre of Western Central India

Introduction: Cataract is a major cause of blindness, but it can be eliminated by surgical management. The visual outcome depends upon the competency of the surgeon, and quality training can contribute to the creation of such skilled surgeons. Methods: This is a retrospective study in which we enrolled all the cataract cases operated between 2004 and 2018, any complication and its repair reported in pretested online form, and all documented post-operative data. All these data were exported to excel sheet from EMR and analysed using SPSS22. Results: Our cohort involved 2998(2.49%) cases out of 120,000 total cataract operated cases. Out of complications documented for45.5% did not require surgical intervention, 30% eyes required secondary implant and remaining cases required other surgeries. Intervention medical and surgical has made significant difference in visual outcome. (p=0.002) 43.9% complications reported during stage of cortical clean up. Primary surgery and trainee categories did not cause significant differences in the visual outcome. Original Research Article Shah et al.; OR, 12(3): 14-20, 2020; Article no.OR. 56874 15 Conclusion: Cataract surgeries done by trainee surgeons caused complications at various stages. However, interventions by vitreo-retinal surgeons led to a significant difference in the final visual outcome.
Block diagonalization precoding and power allocation for clustering small-cell networks

The clustering network is a solution to improve data-rate transmission in small-cells. In this case, clustering small-cells (CSCs) adopt a multiple antennas concept. The multiple antennas are used to maximize the downlink data-rate transmission at the users, but it requires precoding techniques to minimize interference among CSC users. This paper proposes a block diagonalization (BD) as a precoding technique for minimizing interference among CSC users. The performance of the BD precoding implemented on the clustering network under various numbers of small-cells. The CSC also implements a water-filling power allocation (PA-CoopWF) to distribute the available transmission power along with the CSCs antennas. To show the performance, our paper simulates two types of precoding techniques; those are the proposed BD and minimum mean square error (MMSE) in CSCs. Based on the receiver user parts under the overlapping coordination of CSCs, our method based on the BD precoding achieves considerably higher data-rate transmission compared to the MMSE precoding, especially on larger clusters. The simulation also shows that by implementing CSC with the BD in short-range distances and higher numbers of antennas, it promotes better data-rate performances compared to the MMSE precoding by 2.75 times at distance 100m and 67% at 50 antennas.
Curse or Blessing ?-Challenges of Commodity-Based Economies

The idea that massive natural resource endowments would lead countries to weak economic growth and development is counterintuitive. Oil, gas, copper, gold or other resource riches should, at least in theory, spearhead countries with such natural wealth to growth that parallels non-commodity-based economies and help them achieve high-income status. This has not been the case for majority of the endowed countries particularly in North Africa, the Middle East and Latin America. With few exceptions, such as Norway, Botswana, Chile or Australia, the resources proved to be a curse. I begin with a survey of previous academic literature and research on the effects of natural resources on a given country's economic, social and political development. I then move to exploring the many challenges and pitfalls faced by resource-based economies. Such concepts as the Dutch Disease, Rentier State, Governance and Corruption are discussed. In the final section, outline different methods of the resource curse management by first exploring monetary and fiscal policies, and later touching upon the issues of responsible governance. I conclude by proposing a multi-step framework for resource management. Thesis Supervisor: Roberto Rigobon Professor of Applied Economics MIT Sloan School of Management
Effect of Premelting on Conductivity of DNA-Lipid Films

We have measured temperature-dependent (between 20 and 80∘C) electrical conductivity and molecular structure (Raman spectroscopy) of DNA-lipid cast film. Our findings show that the conductivity is strongly influenced by premelting effects in the molecular structure starting near physiological temperatures (∼40∘C), prior to the global DNA denaturation.
High-bandwidth Secondary Voltage and Frequency Control of VSC-based AC Microgrid

This paper proposes a novel secondary control strategy for power electronic-based ac microgrid (MG). This approach restores voltage and frequency deviations by utilizing only local variables with very high bandwidth. This is realized with a finite control set model predictive control (FCS-MPC) technique that is adopted in the inner level of primary control of voltage source converters (VSCs). In the outer level of primary control, droop control and virtual impedance loops are exploited to adjust power sharing among different DGs. As inner control level operates with a very high bandwidth, need for filtering of calculated active and reactive powers in the outer level of primary control is insignificant. Therefore, secondary control can be operated with far superior bandwidth compared to the case when conventional cascaded linear control is used. Merits of the proposed approach are investigated analytically with the help of describing function (DF) methodology that allows quasi-linear approximation of the inner control level. Finally, simulation and experimental results are presented.