Miracle-dz/UniFAR-FTUs huggingface dataset:
A Case Study and Characterization of a Many-socket, Multi-tier NUMA HPC Platform

As the number of processor cores and sockets on HPC compute nodes increase and systems expose more hierarchical non-uniform memory access (NUMA) architectures, efficiently scaling applications within even a single shared memory system is becoming more challenging. It is now common for HPC compute nodes to have two or more sockets and dozens of cores, but future generation systems may contain an order of magnitude more of each. We conduct experiments on a state-of-the-art Intel Xeon Platinum system with 12 processor sockets, totaling 288 cores (576 hardware threads), arranged in a multi-tier NUMA hierarchy. Platforms of this scale and memory hierarchy are uncommon today, providing us a unique opportunity to empirically evaluate-rather than model or simulate-an architecture potentially representative of future HPC compute nodes. We quantify the platform's multi-tier NUMA patterns, then evaluate its suitability for HPC workloads using a modern HPC metagenome assembler application as a case study, and other HPC benchmarks with a variety of parallelization techniques to characterize the system's performance, scalability, I/O patterns, and performance/power behavior. Our results demonstrate near-perfect scaling for embarrassingly parallel and weak scaling workloads, but challenges for random memory access workloads. For the latter, we find poor scaling performance with the default scheduling approaches-e.g., which do not pin threads-suggesting that userspace or kernel schedulers may require changes to better manage the multi-tier NUMA hierarchies of very large shared memory platforms.
Corporate social responsibility (CSR) in Canadian family firms

PurposeThe purpose of this paper is to examine corporate social responsibility (CSR) activities in Canadian family firms.Design/methodology/approachThis paper is an empirical work using a sample of Canadian listed companies for eight years between 2010 and 2017.FindingsRelying on five measures for CSR, this paper finds that, compared with other listed firms, family listed firms have a higher level of CSR engagement. Further tests show that family-named family firms engage in more CSR activities; family firms with second largest shareholders engage in more CSR activities; and family firms affiliated with large business groups engage in more CSR activities. However, family firms whose family members are CEOs, presidents or board chairpersons engage in less CSR engagement.Originality/valueThis paper contributes to the current CSR literature by highlighting the importance of family firm heterogeneity in shaping a firm’s CSR practices. It focuses on four characteristics of Canadian family firms that are potentially connected to CSR, namely, family-named family firms; family firms with family members being CEOs, presidents or chairpersons; family firms with second largest shareholders and family firms affiliated with large business groups.
Comparison of Cryotop and ReproCarreir products for cryopreservation of bovine blastocysts through survival rate and blastocysts quality

Cryopreservation is used for blastocyst preservation of most mammalian embryos and is an important technique for breeding. We aimed to compare the efficiency of the cryopreservation method using the standard Cryotop device and the ReproCarrier device, a domestic product manufactured in Korea. The efficacy of the two devices was analyzed based on the survival rate, intracellular levels of reactive oxygen species (ROS), and apoptosis of the vitrified bovine blastocysts. The survival rates of the vitrified-warmed blastocysts were similar between the ReproCarrier group (58.4 ± 17.7%) and Cryotop group (59.9 ± 14.1%). Intracellular ROS levels and apoptotic index were determined by DCFDA staining and TUNEL assay. Changes in intracellular ROS levels, number of total nuclei, and cellular apoptosis of vitrified blastocysts after cryopreservation were not significantly different between the two groups. These results indicate that the ReproCarrier device method is as effective as the standard Cryotop method for vitrification of bovine blastocysts in vitro.
Usefulness of Using Alternative Body-Mass Index and Neck Circumference Criteria for STOP-Bang Questionnaire in Screening South Korean Obstructive Sleep Apnea Patients

Background and ObjectiveaaThe conventional criteria for body-mass index (BMI > 35 kg/m2) and neck circumference (NC > 40 cm) in the snoring, tiredness, observed apnea, high blood pressure, BMI, age, NC, and gender (STOP-Bang) Questionnaire may be too high to screen Korean obstructive sleep apnea (OSA) patients properly. We hypothesized that using a modified STOP-Bang Questionnaire with lower BMI and NC criteria may be more appropriate when screening South Korean patients with OSA. We aimed to evaluate the utility of the modified STOP-Bang Questionnaires and to compare it with that of conventional STOP or STOP-Bang Questionnaire. MethodsaaThis was a cross-sectional single-center study done at Kyung Hee University Hospital at Gangdong. Consecutive patients who underwent polysomnography and had done the STOPBang Questionnaire between November 2010 and December 2017 were reviewed. We used alternative cut-off criteria for BMI as 30 kg/m2 and for NC as 36.3 cm. ResultsaaA total of 778 patients was evaluated; 73.1% of them had some OSA [apnea-hypopnea index (AHI) > 5/hr] and 54.5% had moderate to severe OSA (AHI > 15/hr). The area under the curve (AUC) of the modified STOP-Bang was slightly larger than for the conventional STOP-Bang or STOP for having any OSA (AUC 0.787, 0.781, and 0.765, respectively) or for moderate to severe OSA (AUC 0.749, 0.747, and 0.721). The conventional STOP-Bang Questionnaire with a cut-off score of 3 identified all OSA and moderate to severe OSA patients with a sensitivity of 94.7% and 96.9%, respectively. The modified STOP-Bang showed improved sensitivity for any or moderate to severe OSA of 95.6% and 98.1%, respectively, with a decrease in exchange for lower specificity. ConclusionsaaBecause of the high prevalence of undiagnosed OSA, the modified STOP-Bang might be more appropriate in screening South Korean patients with OSA. Sleep Med Res 2020;11(1):38-43
Impact of Cereal+legume Intercropping Systems on Productivity and Soil Health -A Review

offers many benefits likeinsurance against total crop failure, assured or increased yield and biomass,less weed, pest and diseasemenace.The choice of compatible crops for an intercropping system depends on several factors like growth habit, ideotype, land, light, water and fertilizer utilization. In this article, we have focused only on cereal+legume intercropping systems as their associationhelp in improves soil fertility and enhance productivity. However, this cropping system have also great importance in rainfed situation, particularly Maize based intercropping system with wheat cropping sequence. We hope that this review report willprovide a valuable guideline for the researchers, extension functionaries and other stakeholders those working on intercropping systems. Abstract
TENT: Uma Ferramenta Para Formação de Equipes que Considera Fatores Socioafetivos

The technical aspects and social affinity are parameters commonly used to create teams in the academic context. However, other socio-affective factors can also present satisfactory results when used in the formation of teams. This research aims to create a tool capable of assisting in the formation of teams, considering such factors and their affinities. The Design Science Research methodology was adopted to create the TENT tool. Based on the experiments, we concluded that the teams had more affective connections than antithetical ones. We conclude that the algorithm can assemble teams so that their members have similar characteristic types, avoiding antithetical characteristic types. Resumo. Os aspectos técnicos e de afinidade social são parâmetros comumente utilizados para criação de equipes no contexto acadêmico. No entanto, outros fatores socioafetivos também apresentam resultados satisfatórios quando utilizados na formação das equipes. Essa pesquisa tem como objetivo a criação de uma ferramenta capaz de auxiliar na formação de equipes, considerando tais fatores e suas afinidades. A metodologia de Design Science Research foi adotada para a criação da ferramenta TENT. Diante dos experimentos realizados, as equipes tiveram mais ligações afetivas do que ligações antitéticas. Contudo, percebe-se que a ferramenta forma equipes de maneira que seus integrantes tenham tipos caracterı́sticos afins, evitando tipos caracterı́sticos antitéticos.
Development of Cascaded Multilevel Inverter Based Active Power Filter With Reduced Transformers

Active power filter is a power electronic converter used for improving the quality of supply by eliminating the effect of harmonics due to non-linear loads. This paper recommends a concept for shunt active power filter (SAPF) using a single power source fed to a cascaded multilevel inverter (CMI) with 3-φ transformers. Apart from traditional transformer based topologies, the required number of transformers are substantially reduced, resulting in less space requirement, which leads to low cost and simple control system. The proposed CMI based SAPF has a capacity to compensate for contaminated load with high harmonic and a low power factor. The effective i d -i q theory is used to calculate compensation currents. DC link voltage regulator analyzed through delay time and controller gain. The tasks of the controller in the SAPF can perform all necessary actions for correct operation in SAPF. A wide range of computer simulation results demonstrated and validated the results with the prototype experimental setup.
On Minimizing Cost of Reliable Network Topological Design using a Practical DP Approach

This paper addresses an NP-hard problem called NTD-CR that using dynamic programming (DP) scheme. This problem referred to as Network Topology Design with minimum Cost subject to a Reliability constraint. It designs a minimal-cost communication network topology that satisfies a pre-defined (s, t) terminal reliability constraint. Our DP approach, called DPCR-L, mainly select the set of possible links to be deleted from the original network to generate an optimal Network Topology. The NTD-CR design problem aims to find a Network Topology that has minimal cost with the required reliability for the network. Five link-ordering criteria are proposed to improve the performance of DPCR-L. Each greedy heuristic order allows DPCR-L to enumerate the selected deleted links, which improves the time complexity while producing near optimal topology. Extensive Simulations based on different benchmark networks of various sizes are used to compare DPCR-L with existing state-of-the-art techniques and show the merits of using the ordering methods, and the effectiveness of our algorithm. Our simulations show that DPCR-L produces 93% optimal results. Interestingly, of the non-optimal results, DPCR-L produces a network with reliability no worse than 5.38% off optimal, and most of the non-optimal results have a lower cost than that for optimal up to 0.17%. Typically, for the most of the network topologies, DPCR-L generates NT with the same or better 2-terminal reliability measure and speeds up its running time up to 31.71%. Furthermore, simulation results on large size networks show that DPCR-L speeds up the process with up to (47.28%) compared to the recent existing approach. Finally, the results present the applicability of DPCR-L on networks containing a large number of links and demonstrated better performance and computationally more efficient than other existing algorithms.
Effect of the combination of 25-hydroxyvitamin D3 and higher level of calcium and phosphorus in the diets on bone 3D structural development in pullets

Bone issues such as osteoporosis are major concerns for the laying hen industry. A study was conducted to improve bone-health in pullets. A total of 448 one-day-old Hyline W36 pullets were randomly assigned to four treatments (8 rep; 14 birds/rep) until 17 weeks (wks). Dietary treatments were: 1) vitamin D3 at (2,760 IU/kg) (D), 2) vitamin D3 (2,760 IU/kg)+62.5 mg 25-(OH)D3/ton (H25D), 3) vitamin D3 (2,760 IU/kg) + 62.5 mg 25-(OH)D3/ton + high Ca&P (H25D + Ca/P), and 4) vitamin D3 (2,760 IU/kg) + high Ca&P (D + Ca/P). The high calcium (Ca) and phosphorus (P) diet was modified by increasing both high calcium and phosphorus by 30% (2:1) for the first 12 wks and then only increasing P for 12–17 wks to reduce the Ca to P ratio. At 17 wk, growth performance was measured, whole body composition was measured by dual energy x-ray absorptiometry (DEXA), and femur bones were scanned using Micro-computed tomography (Micro-CT) for bone 3D structure analyses. The data were subjected to a one-way ANOVA using the GLM procedure, with means deemed significant at p < 0.05. There was no significant outcome for growth performance or dual energy x-ray absorptiometry parameters. Micro-computed tomography results indicated that the H25D + Ca/P treatment had lower open pore volume space, open porosity, total volume of pore space, and total porosity in the cortical bone compared to the D + Ca/P. It also showed that a higher cortical bone volume/tissue volume (BV/TV) in the H25D + Ca/P than in the D + Ca/P. Furthermore, the H25D + Ca/P treatment had the lowest trabecular pattern factor and structure model index compared to the other treatments, which indicates its beneficial effects on trabecular structural development. Moreover, the H25D + Ca/P had a higher trabecular percentage compared to the D and 25D, which suggests the additional high calcium and phosphorus supplementation on top of 25D increased trabecular content in the cavity. In conclusion, the combination of 25D with higher levels of high calcium and phosphorus could improve cortical bone quality in pullets and showed a beneficial effect on trabecular bone 3D structural development. Thus, combination of a higher bio-active form of vitamin D3 and higher levels of high calcium and phosphorus could become a potential feeding strategy to improve bone structural integrity and health in pullets.
Time-Series Classification Based on Fusion Features of Sequence and Visualization

For the task of time-series data classification (TSC), some methods directly classify raw time-series (TS) data. However, certain sequence features are not evident in the time domain and the human brain can extract visual features based on visualization to classify data. Therefore, some researchers have converted TS data to image data and used image processing methods for TSC. While human perceptionconsists of a combination of human senses from different aspects, existing methods only use sequence features or visualization features. Therefore, this paper proposes a framework for TSC based on fusion features (TSC-FF) of sequence features extracted from raw TS and visualization features extracted from Area Graphs converted from TS. Deep learning methods have been proven to be useful tools for automatically learning features from data; therefore, we use long short-term memory with an attention mechanism (LSTM-A) to learn sequence features and a convolutional neural network with an attention mechanism (CNN-A) for visualization features, in order to imitate the human brain. In addition, we use the simplest visualization method of Area Graph for visualization features extraction, avoiding loss of information and additional computational cost. This article aims to prove that using deep neural networks to learn features from different aspects and fusing them can replace complex, artificially constructed features, as well as remove the bias due to manually designed features, in order to avoid the limitations of domain knowledge. Experiments on several open data sets show that the framework achieves promising results, compared with other methods.
Evaluation of Troponin I Serum Level in Patients With Peritoneal Dialysis and Relationship Between Troponin I and Cardiovascular Risk Factors

End-stage renal disease is a situation that predisposes the patients to cardiovascular disease, especially myocardial infarction (MI). A valuable biomarker for the diagnosis of this event is cardiac troponin. Although some asymptomatic patients show high plasma levels of cardiac troponin I, it is still the most sensitive variable in MI. All patients more than 18-year-old, on chronic ambulatory peritoneal dialysis (CAPD) for at least three months, and did not have a history of acute myocardial infarction or hospitalization for CVD during last month are included in a cross-sectional descriptive study. Troponin I serum level was measured by VIDAS Troponin I Ultra (TNIU) Assay. Correlation between serum troponin level and cardiovascular risk factors are evaluated. In this study, 52% of patients were male. The mean cTnI level was 0.025±0.044 ng/mL, less than 0.11 ng/mL, and only five patients had cTnI level more than the laboratory threshold. The cut-off level of cTnI for diagnosing cardiovascular disease must be re-evaluated and maybe increase to 0.3 ng/mL. Indeed, the asymptomatic patient may need more close observation for cardiovascular disease. © 2019 Tehran University of Medical Sciences. All rights reserved.
Activity of photosynthetic Reaction Centers coated with polydopamine

Dilute aqueous solutions of dopamine buffered to an alkaline pH and in the presence of dissolved oxygen undergo to a series of autoxidation and rearrangement reactions that lead to the formation of a dark insoluble material called polydopamine (PDA) with melanin reminiscent properties. In this work we carried out this reaction in the presence of the photosynthetic reaction center (RC), a transmembrane pigment-protein complex responsible for the first light-induced reactions in the photosynthetic process. We have found that PDA grows in colloidal form around the RC and in the appropriate conditions the protein is entrapped in the PDA matrix without loss of functionality. The protein is still capable to perform its natural photocycle leading to the generation of photocurrents and the ubiquinone acceptor complex function is modulated by the PDA/RC ratio.
Effet de l'acide mycophénolique sur les voies de signalisation activées par des agents pro-inflammatoires dans la cellule dendritique humaine

Initialement developpes pour leur action inhibitrice sur les lymphocytes T, les immunosuppresseurs affectent aussi les cellules dendritiques (CD). Nous avons precedemment montre que l’acide mycophenolique (MPA) induisait une resistance des CD humaines a la maturation, neanmoins son mecanisme d’action sur les CD reste meconnu. Ce travail de these montre que le MPA inhibe l’activation de p38MAPK et que cette propriete entraine l’inhibition de la maturation phenotypique induite par le facteur necrotique tumoral a (TNFa), la diminution de la secretion de cytokines pro-inflammatoires et de la capacite allostimulatrice induite par le TNFa ou le lipopolysaccharide suggerant que l’inhibition de la synthese de cytokines inflammatoires serait determinante pour inhiber la capacite allostimulatrice. Nous rapportons egalement que le MPA inhibe la phosphorylation de ERK induite par le TNFa. Ainsi, l’action du MPA sur les CD s’exerce differemment selon l’environnement dans lequel se trouvent les CD.
Adipokines: mediators of immunity and inflammation

White adipose tissue has emerged as a highly dynamic organ that releases a plethora of immune and inflammatory mediators that are involved in obesity, metabolic syndrome and immune mediated diseases. Adipokines have complex role in various physiological and pathological processes by exerting potent modulatory actions on target tissues In this Review, In this review, we explore the effects of different adipokines, focusing primarily on leptin, adiponectin, visfatin and resistin in causing immune-mediated and/or inflammatory diseases.
Piety and profit; the moral embeddedness of an enterprising community

ABSTRACT We are interested in how morality can be sustained in entrepreneurial practice. We examine the interesting case of the Hutterites, a communal society who practice community entrepreneurship – entrepreneuring by the community and for the community. Arguing that culture provides values and that morals are cultural artefacts – we show how ethics determine the entrepreneurial practices of this remarkably successful entrepreneurial society. Our analysis explains how in this close-knit society, cultural morals and ethics of practice are perfectly aligned, embodied in practice and determine how entrepreneurship is practiced. The result is an economically viable society that preserves its ancient way of life and combines piety and profit. We demonstrate how cultural values shape entrepreneurial practice and how enterprising in this community is a change mechanism, yet also maintains social stability.
Üniversite Öğrencilerinin İşsizlik Kaygısı

When an individual have the feeling that something bad will happen, concern or apprehension, the feeling he/she feels perceive of anxiety. In Turkey and the world unemployment which is one of the biggest problems causes unemployment anxiety in job seekers. In university senior students the thought of not being able to find a job after graduating and job uncertainty causes students to experience unemployment anxiety. The aim of this study is to determine whether university senior students experience unemployment anxiety and to investigate whether there is a difference between students' unemployment anxiety according to demographic characteristics. The study was applied to a total of 139 senior students at Nevsehir Haci Bektas Veli University Faculty of Art and Science. A survey was conducted to determine the unemployment anxiety level and demographic characteristics of students. The answers were entered into the SPSS package program and tried to test the research hypotheses. In the study, factor analysis, which is one of the multivariate statistical analyzes, was used to classify the variables. Independent samples t-test and one-way analysis of variance were used to examine the hypotheses of the study. To evaluate the differences at the sub-dimensions, the unemployment anxiety sub-dimensions were determined. It was determined that there is a difference in the unemployment anxiety dimensions according to the demographic characteristics of area, departments, gender, settlement areas and overall grade average.
Transglutaminase 2 regulates terminal erythroid differentiation via cross-linking activity

Transglutaminase 2 (TGM2) is a versatile enzyme that modulates cell survival and differentiation. However, its role in terminal erythroid differentiation is poorly understood. In this study, we investigated the function of TGM2 in primary fetal liver erythroid differentiation. We predicted TGM2 as an upstream regulator via ingenuity pathway analysis (IPA), and found that its expression was increased at both RNA and protein level during terminal erythroid differentiation. TGM2 cross-linking activity inhibitors GK921 and Z-DON suppressed erythroid maturation and enucleation, while its GTPase inhibitor LDN27219 had no such effect. Z-DON treatment arrested differentiation at basophilic erythroblast stage, and interfered with cell cycle progression. RT-PCR demonstrated decreased GATA-1 and KLF1, and disarranged cyclin, CDKI and E2F family genes expression after Z-DON treatment. In conclusion, TGM2 regulates terminal erythroid differentiation through its cross-linking enzyme activity.