Miracle-dz/UniFAR-FTUs huggingface dataset:
Relationship between regular walking, physical activity, and health-related quality of life.

BACKGROUND The current physical activity (PA) and health-related quality of life (HRQoL) literature warrants further investigation with general population samples. The exploratory-focused purpose of this study was to compare total PA-HRQoL and walking-HRQoL relations, include a measure of general happiness, and to evaluate potential activity-HRQoL demographic moderators. METHODS A random sample of 351 adults completed an adapted Godin Leisure Time Questionnaire, the SF-36, and the Satisfaction with Life Scale. RESULTS Partial correlations revealed small-to-moderate associations between walking/total PA and general health, vitality, and social functioning after controlling for key demographics (P < 0.05). A dependent t-test determined walking and PA as equally related to vitality and social functioning. Multiple regression revealed annual income as a moderator of the total PA/walking-social functioning relationship [F(3,315) = 9.71 and F(3,316) = 12.03, P < 0.01, respectively]. CONCLUSIONS HRQoL may be considered with walking interventions and annual income. The contribution of PA to overall happiness appears to be minor.
Helping Young Men Thrive: Positive Youth Development and Men’s Health

Positive youth development (PYD) is a strong and growing field that complements the traditional problem-focused view of youth, and describes and promotes the healthy development and positive outcomes of young people. The PYD perspective can be applied in clinical and community intervention settings. Frameworks such as the “Five Cs” and the Search Institute’s developmental assets model have guided researchers and practitioners in better understanding the process of PYD and the effectiveness of community interventions to promote PYD. The PYD literature lacks a coherent guiding framework to describe gender differences in positive development, which in turn could guide community and clinical interventions designed to help young men thrive.
Low-cost Monitoring and Control for Multi-dimensional Time

An important class of statically-analyzable loops is affine control loops (ACLs). Expected value signals related to fluid preference, the expected magnitude, or probability of reward were decoded simultaneously with the intended goal. An inverse method was also used by previous investigators to reconstruct the input signal of a saccade from the Fourier transform of the padded and mirrored position profile and the impulse response of the system model. In this paper, we present the application of independent component analysis (ICA) to decompose the components of saccade and vergence eye movements.
Lhx9 and Lhx9alpha LIM-homeodomain factors: genomic structure, expression patterns, chromosomal localization, and phylogenetic analysis.

Lhx9 is a LIM-homeodomain (LIM-hd) transcription factor expressed in the embryonic mouse brain. We report the isolation of Lhx9alpha, a cDNA encoding a truncated isoform of Lhx9 that lacks the recognition helix of the homeodomain and differs from Lhx9 cDNA in its 3'-coding and 3'-UTR sequences. Isolation of the Lhx9 gene showed that Lhx9 and Lhx9alpha are coded by six exons spanning 10 kb of genomic sequence and that Lhx9alpha is an isoform generated by alternative splicing of the fifth exon. Lhx9 was mapped to the subtelomeric region of chromosome 1. Further molecular analysis showed that Lhx9 is a new candidate gene for the unidentified dreher (dr) mutation in mouse. The comparison of genomic structure and molecular phylogenetic analysis led to the identification of six groups of LIM-hd proteins, a basis for further classification and knowledge of their evolutionary relationships. To investigate a possible role for Lhx9alpha, the expression patterns of Lhx9 and Lhx9alpha were compared during embryogenesis. Lhx9alpha was expressed at lower levels than Lhx9, with a similar but distinct pattern in the brain, especially in the neocortex. We suggest that Lhx9alpha could function as an endogenous dominant-negative form of Lhx9 during development, both to regulate in space and time the transcriptional effects of Lhx9 and to add a degree of refinement to the LIM-hd code.
"Central" auditory gap detection: a spatial case.

Normal listeners were tested for their temporal auditory gap detection thresholds using free-field presentation of white-noise stimuli delivered from the left (L) and right (R) poles of the interaural axis. The noise bursts serving as the leading and trailing markers for the silent period were presented in either the same (LL,RR) or different (LR,RL) auditory locations. The duration of the leading marker was a second independent variable. Gap thresholds for stimuli in which the markers had the same location were low, and usually were independent of the duration of the leading marker. Gap thresholds for the LR and RL conditions were longer. These gap thresholds were sensitive to the duration of the leading marker, and increased as the leading marker duration decreased. This finding is consistent with the hypothesis that a relative timing operation mediates gap detection when the markers activate different perceptual channels. The present data suggest that this timing process can operate on perceptual channels emerging from central nervous system processing.
Beta-lactam antibiotic decreases acquisition of and motivation to respond for cocaine, but not sweet food, in C57Bl/6 mice

No medication is approved to treat cocaine addiction, but mounting evidence suggests that glutamate-directed approaches may reduce cocaine dependence and relapse. We tested the hypotheses that the glutamate transporter subtype 1 activator, ceftriaxone, disrupts acquisition of cocaine self-administration, motivation to self-administer cocaine, and conditioned place preference in mice. Repeated ceftriaxone (200 mg/kg) reduced the ability of mice to acquire cocaine and the motivation to self-administer cocaine after successful acquisition without affecting acquisition of or motivation for sweet food. Repeated ceftriaxone had no effect on cocaine-conditioned place preference. These results suggest that a &bgr;-lactam antibiotic reduces the direct reinforcing strength of cocaine without producing nonspecific deficits in conditioned learning processes.
Study of morphological characteristics, pathogenicity and drug resistance ofCandida glabrata as increasing opportunistic yeast

Recent decades can be a milestone in the advancemen t of medical science with the help of modern tools and drugs including use of antibiotics, corticosteroids, immu nosuppressive drugs, different types of transplanta tion , etc. Furthermore, with industrialization of human societ y and change of their lifestyle, some human disease s have prevailed, such as increasing in mental illness, AI DS, diabetes, Lupus Erythematous , etc. Besides all of mentioned cases, the way has been opened to expanse of opportunistic infections and the emer gence of less common cases. Candidiasis is a common fungal disease that in recent decades h as been encountered with changes of type of etiologic agent and patterns of drug resistance . Candida glabrata can be accounted as emerging species with specific changes, therefore it is necessary to know this organism and make efforts to eliminate it. In this paper we try to introduce some of the most common disease of C. glabrata, its appearance changes, and also some of the most prominent causes of its disease increasing.
The relationships between market orientation and alternative strategic orientations: A meta‐analysis

Purpose – One of the strongest convictions in marketing is that market orientation contributes to firms' performance substantially more than alternative strategic orientations such as innovation and entrepreneurial orientations. Still, some studies show that alternative orientations can also substantially affect the performance of firms, and furthermore, that firms that combine market orientation with alternative orientations are likely to perform even better than firms adopting only market orientation. Also, the nature of the relationship between market orientation and other strategic orientations is not clear. The purpose of this paper is to deal with these discrepancies in the marketing literature. It highlights the importance of the study of the relationship between market orientation and alternative strategic orientations, examines the effect of market orientation on different orientations, and identifies the orientations that are more likely to be combined with market orientation.Design/methodology/.
Low Variance Blind Estimation of the Reverberation Time

The reverberation time is a key feature for describing the acoustic properties of a reverberant room. It can be computed from a measured Room Impulse Response but in many applications it has to be estimated blindly. Existing blind methods give accurate estimates but they often exhibit high variance across different speakers. In this paper, a low variance blind estimator of the reverberation time is derived from the decay rate distribution of the signal. The influence of the reverberation time on the statistical moments of the distribution is analyzed and one relevant moment is taken as an estimator. The variance of the estimator is reduced thanks to a prewhitening filter and a modification of the decay rate distribution. Experimental results confirm the accuracy of the method when the observed signal is sufficiently long.
Drug induced acute interstitial nephritis

Acute interstitial nephritis is characterized by inflammatory infiltration and edema in renal insterstitium and is associated with acute failure in renal functions. The most frequent cause of AIN is drug use which is responsible approximately 60-70% of AIN cases and antibiotics are the leading among almost all kinds of medication classes. Hypersensitiviy reactions to a certain drug or any metabolites of a drug play a major role in AIN pathogenesis. Regardless from etiologic factor, most of AIN patients refer to hospital with non-specific symptoms (nausea, vomiting, fatique etc.) or acute failure findings of renal functions. Renal biopsy is the gold standard in diagnosis of AIN, revealing classical pathologic sign of inflammatory infiltration in renal interstitium. When diagnosis of AIN is certain, suspected drug must be discontinued instantly and oral or intravenous steroid therapy must be started immediately. Steroid therapy has a positive correlation with rapid and complete remission, but total recovery may not be achieved in all cases. In this review, we tried to look over this illness which needs more attention in clinical practice.
Effect of basin physical characteristics on solute fluxes in nine alpine/subalpine basins, Colorado, USA

Alpine/subalpine basins may exhibit substantial variability in solute fluxes despite many apparent similarities in basin characteristics. An evaluation of controls on spatial patterns in solute fluxes may allow development of predictive tools for assessing basin sensitivity to outside perturbations such as climate change or deposition of atmospheric pollutants. Relationships between basin physical characteristics, determined from geographical information system (GIS) tools, and solute fluxes and mineral weathering rates were explored for nine alpine/subalpine basins in Rocky Mountain National Park, Colorado, using correlation analyses for 1993 and 1994 data. Stream‐water nitrate fluxes were correlated positively with basin characteristics associated with the talus environment; i.e., the fractional amounts of steep slopes (≥ 30°), unvegetated terrain and young debris (primarily Holocene till) in the basins, and were correlated negatively with fractional amounts of subalpine meadow terrain. Correlations with nitrate indicate the importance of the talus environment in promoting nitrate flux and the mitigating effect of areas with established vegetation, such as subalpine meadows. Total mineral weathering rates for the basins ranged from about 300 to 600 mol ha−1 year−1. Oligoclase weathering accounted for 30 to 73% of the total mineral weathering flux, and was positively correlated with the amount of old debris (primarily Pleistocene glacial till) in the basins. Although calcite is found in trace amounts in bedrock, calcite weathering accounted for up to 44% of the total mineral weathering flux. Calcite was strongly correlated with steep slope, unvegetated terrain, and young debris—probably because physical weathering in steep‐gradient areas exposes fresh mineral surfaces that contain calcite for chemical weathering. Oligoclase and calcite weathering are the dominant sources of alkalinity in the basins. However, atmospherically deposited acids consume much of the alkalinity generated by weathering of calcite and other minerals in the talus environment. Published in 2001 by John Wiley & Sons, Ltd.
[Univariate analysis of syndrome differentiation in traditional Chinese medicine and clinical correlative factors in gastric cancer].

OBJECTIVE The research is aimed at investigating the developing rule and the relationship between syndrome differentiation in traditional Chinese medicine (TCM) and clinical factors of gastric cancer, so that it can be helpful to the clinical work and indicating the prognosis. METHODS We collected the medical records and the information of four diagnostic methods of 325 cases of gastric cancer sufferers in the way of clinical epidemiological survey, and divided them into 6 syndromes including dysfunction of spleen, disharmony of liver and stomach, blood stagnation in stomach, yin deficiency of stomach, phlegm dampness stagnation and deficiency of both qi and blood. Then we used univariate analysis of variance, rank sum test and chi square test to analyse the relationship between syndrome differentiation and clinical-related factors such as age, gender, Karnofsky score and clinical stage, etc. RESULTS The syndrome of dysfunction of spleen plays the primary role in the disease. Disharmony of liver and stomach always happens in early stage of stomach cancer, usually more often in radical operation cases and less in metastasis ones. It also has a high proportion in female. Phlegm dampness stagnation and blood stagnation in stomach usually can be seen in middle or advanced stage of the disease, which have lower Karnofsky score. Deficiency of both qi and blood is the syndrome of stomach cancer in advanced stage, which results in lower living quality, and with high rate of relapse and metastasis. Syndrome of yin deficiency of stomach has lower proportion in stomach cancer cases, and the clinical-related factors have low influence on it. CONCLUSION Syndrome in TCM of gastric cancer is relevant to some clinical factors and varies in progress.
Similarity-based modeling of aircraft flight paths

Modeling methods based on historical data can be used to model the values of parameters describing the flight paths of both military and commercial jet aircraft. Flight path parameters that are modeled typically include: pilot inputs such as the positions of the stick or control column and control wheel, power levers, rudder pedal, and controls for the slats, spoilers, stabilizer, and landing gear; control surface and controller responses such as the positions of the ailerons, elevators, flaps, rudder, slats, spoilers, stabilizer, and fuel flows; and aircraft responses such as airspeed, altitude, angle of attack, acceleration components, pitch, roll, yaw, the speeds of the low-pressure and high-pressure turbines, and exhaust gas temperatures. The utility of the models lies in their ability to confirm normal behavior and to detect abnormal behavior of control surfaces and engine systems during takeoff, cruise, and landing. Examples of several methods applied to a newly manufactured military jet to confirm acceptance test results during an entire flight are illustrated. Also illustrated are examples of several methods applied to the analysis of a commercial jet aircraft incident involving a control surface failure during a landing approach, an analysis that illustrates the capability of the method to support fault isolation. One of the versions, a similarity-based modeling method, exhibits a superior ability to achieve the intended purposes.
Multi-level clustering architecture and protocol designs for wireless sensor networks

Wireless sensor network (WSN) consists of a number of sensors, which measure and gather data in a variety of environments. In a WSN, sensed data are collected at a centralized location, called sink, for processing and analysis. With limited transmission ranges, sensed data may require multiple relays to reach the sink. In this thesis, a novel system design for multi-level clustering (MLC) WSNs and its associated protocol operations are proposed. Cluster-heads in the proposed design form a tree with a goal to reach all sensor nodes in the network. Subsequently, all sensed data in the tree are delivered to the sink. Energy savings is improved by exploiting sensor node redundancy in the WSN. To validate the proposed design, thorough simulations have been carried out. Upon comparing to the LEACH protocol, it offers consistent wider coverage area and longer life span of a WSN with proper settings of system parameters.
Brain temperature and exercise performance

Events arising within the central nervous system seem to be a major factor in the aetiology of hyperthermia‐induced fatigue. Thus, various studies with superimposed electrical nerve stimulation or transcranial magnetic stimulation have shown that both passive and exercise‐induced hyperthermia will impair voluntary motor activation during sustained maximal contractions. In humans, the brain temperature increases in parallel with that of the body core, making it very difficult to evaluate the independent effect of the cerebral temperature. Experiments with separate manipulation of the brain temperature in exercising goats indicate that excessive brain hyperthermia will directly affect motor performance. However, several homeostatic changes arise in parallel with hyperthermia, including factors that may influence both peripheral and central fatigue, and it is likely that these changes interact with the inhibitory effect of an elevated brain temperature.
Integration of alien plants into a native flower–pollinator visitation web

Introduced alien species influence many ecosystem services, including pollination of plants by animals. We extend the scope of recent ‘single species’ studies by analysing how alien plant species integrate themselves into a native flower visitation web. Historical records for a community in central USA show that 456 plant species received visits from 1429 insect and 1 hummingbird species, yielding 15 265 unique interactions. Aliens comprised 12.3% of all plant species, whereas only a few insects were alien. On average, the flowers of alien plants were visited by significantly fewer animal species than those of native plants. Most of these visitors were generalists, visiting many other plant species. The web of interactions between flowers and visitors was less richly connected for alien plants than for natives; nonetheless, aliens were well integrated into the native web. Because most visitors appear to be pollinators, this integration implies possible competitive and facilitative interactions between native and alien plants, mediated through animal visitors to flowers.
Articular contact kinematics of the knee before and after a cruciate retaining total knee arthroplasty

Accurate knowledge of tibiofemoral articular contact kinematics of the knee after total knee arthroplasty (TKA) is important for understanding the intrinsic knee biomechanics and improving the longevity of the components. The objective of this study was to compare the in vivo articular contact kinematics of the knees with end‐stage medial osteoarthritis (OA) during a weight‐bearing, single leg lunge activity before and after a posterior cruciate retaining TKA (CR‐TKA) using a dual fluoroscopic imaging technique. We found that the CR‐TKA resulted in more posterior contact positions on the tibial surface and a reduced range of motion in the medial and lateral compartments. The distances between medial and lateral contact locations in the CR‐TKA knees were statistically larger than the OA knees. The articular contact centers have shifted from medial side of the tibial plateau pre‐operatively to the lateral side after operation. This study indicated that the CR‐TKA resulted in significant changes in contact kinematics of the knees in both anteroposterior and mediolateral directions. Further studies are needed to determine the influence of the altered in vivo contact kinematics on the longevity of polyethylene liner and long term clinical outcomes of the TKA. © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:? –? , 2015.
Organizational knowledge generation: lessons from online communities

– Knowledge capturing and sharing within an organization have been extensively studied in the literature. In this stream of work, an influential focus is on the process of encoding and managing knowledge to enable effective reuse within the organization. With the advancement of internet and web technologies, there is an increased interest in the study of knowledge flows in online communities. The authors highlight in this paper the fact that the boundaries between internal and external organizational knowledge are disappearing, mainly due to the extensive use of online-based platforms to support organizational operations. The authors believe that this will affect the activities of knowledge management in today’s businesses. The purpose of this paper is to provide guidelines for organizations on how to bridge their internal and external knowledge using an integrated semantic approach. , – In this paper the authors review two classes of approaches, those that target internal organizational knowledge, and those that target online knowledge flow processes. Then the authors identify the challenges involved in today’s knowledge environments. To address those challenges, the authors propose a framework to bridge and integrate internal and external organizational knowledge. The authors map the activities handled in the framework to the existing knowledge management activities identified from the literature, and highlight how emerging technologies are used to support such activities along the knowledge management process. The authors apply the approach in the context of an organization’s process that heavily depends on the appropriate alignment of internal and external knowledge. The authors focus on the use of emerging technologies that support collaboration and the generation of explicit and reusable semantics. , – Interaction points within organizations can be used to define the scope of knowledge exchanged. Following a methodology around the proposed framework, it is feasible to create conceptual connections around internal and external knowledge through explicit semantics. Such connections that are created to support online communities’ knowledge exchange can be applied to internal organizational knowledge, and used as a bridge to external knowledge sources. , – The paper provides a roadmap for organizations on how to manage organizational knowledge processes in a coherent and collaborative semantic platform, with a view to what is available outside the boundaries of an organization.