Miracle-dz/UniFAR-FTUs huggingface dataset:
Toward Virtual Reality in Architecture:Concepts and Scenarios from the Architectural Space Laboratory

Virtual reality is the logical step that started way back in time with the appearance of the very first architectural drawing. This has been a long history of development: architectural drawings in Europe, which date back to the tenth century, were the first kind of abstraction that appeared virtually real to potential clients and builders—real enough to base decisions on. With the discovery of perspective techniques, drawings became more refined and developed into a form of art with numerous branches, ranging from technical drawings to presentation drawings. Wooden models appeared even before the Renaissance and were supplemented in the nineteenth century with cardboard models. Each new invention helped to improve the understanding of projects and architecture by reducing abstraction, while increasing the complexity of the representation (Schmitt, 1993). Toward the end of the twentieth century, the majority of architectural projects were and are never realized. Prominent projects, such as the new Berlin Government Centre, result in several hundred professional competition entries. With the advent of virtual reality (VR) techniques, architects will at first intensely criticise the new technology, before adopting and improving it, and they will modify it with domain specific contributions. The knowledge of architectural abstraction and simulation is useful to the further development of VR and vice versa. Today, the newest methodological and technical instruments help designers to create a more responsible architecture, many aspects of which can be experienced and tested before construction. This includes the possibility of expanding the number of senses addressed for the explanation of an architectural idea. To structure the discussion about VR in architecture, we first describe the theoretical framework, then move to the description of a Architectural Space Laboratory at the Architecture Department of the Swiss Federal Institute of Technology, ETH Zürich, and follow this with examples of program development. We conclude with speculations on the impact of the new technology on the architecture of the future.
Döderlein's Vaginal Bacillus: A Contribution to the Study of the Lacto-Bacilli

It is concluded from a study of the morphological and cultural characters of 60 strains of Döderlein's vaginal bacillus that the organism belongs to the lacto-bacillus group of bacteria. Primary culture of Döderlein's bacillus may be readily obtained on lactose blood agar incubated aerobically provided the vaginal flora is of “Grade A” type, but its subsequent propagation on artificial culture media is less likely to be successful. Three morphological types of Döderlein's bacillus are recognised. Cultural and fermentative tests show that these types are all biologically similar. There is no serological homogeneity among the strains of Döderlein's bacillus, although there was some evidence of a serological relationship among the members of the commonest morphological type. The same serological type tends to persist in the vagina throughout pregnancy. Döderlein's bacillus and lacto-bacilli derived from other sources are not serologically identical.
CIGS thin films prepared by sputtering and selenization by using In2Se3, Ga2Se3 and Cu as sputtering targets

CuInGaSe<inf>2</inf>/CdS thin film solar cells were prepared by using a novel precursor obtained by depositing in sequence, on top of a Mo covered soda lime glass, In<inf>2</inf>Se<inf>3</inf>, Ga<inf>2</inf>Se<inf>3</inf> and Cu. A subsequent few minutes selenization of the precursor in a selenium vapor is sufficient to obtain a good quality CuInGaSe<inf>2</inf> film.
Hopanoids play a role in stress tolerance and nutrient storage in the cyanobacterium Nostoc punctiforme

Hopanes are abundant in ancient sedimentary rocks at discrete intervals in Earth history, yet interpreting their significance in the geologic record is complicated by our incomplete knowledge of what their progenitors, hopanoids, do in modern cells. To date, few studies have addressed the breadth of diversity of physiological functions of these lipids and whether those functions are conserved across the hopanoid‐producing bacterial phyla. Here, we generated mutants in the filamentous cyanobacterium, Nostoc punctiforme, that are unable to make all hopanoids (shc) or 2‐methylhopanoids (hpnP). While the absence of hopanoids impedes growth of vegetative cells at high temperature, the shc mutant grows faster at low temperature. This finding is consistent with hopanoids acting as membrane rigidifiers, a function shared by other hopanoid‐producing phyla. Apart from impacting fitness under temperature stress, hopanoids are dispensable for vegetative cells under other stress conditions. However, hopanoids are required for stress tolerance in akinetes, a resting survival cell type. While 2‐methylated hopanoids do not appear to contribute to any stress phenotype, total hopanoids and to a lesser extent 2‐methylhopanoids were found to promote the formation of cyanophycin granules in akinetes. Finally, although hopanoids support symbiotic interactions between Alphaproteobacteria and plants, they do not appear to facilitate symbiosis between N. punctiforme and the hornwort Anthoceros punctatus. Collectively, these findings support interpreting hopanes as general environmental stress biomarkers. If hopanoid‐mediated enhancement of nitrogen‐rich storage products turns out to be a conserved phenomenon in other organisms, a better understanding of this relationship may help us parse the enrichment of 2‐methylhopanes in the rock record during episodes of disrupted nutrient cycling.
Necesidades, retos y propuestas de acción para la formación permanente del profesorado de educación infantil

El trabajo que se presenta a continuacion se enmarca en una investigacion realizada, entre enero y septiembre del ano 2006, sobre la formacion permanente del profesorado de educacion infantil. El objetivo de este articulo no consiste, sin embargo, en la descripcion o el analisis en profundidad de la formulacion, el desarrollo o los resultados de aquella investigacion. Lo que nos interesa es mostrar las propuestas y lineas de accion que el equipo de investigacion elaboro como resultado de las conclusiones obtenidas en el estudio. Entendemos que todas las propuestas de accion que se presentan pueden ayudar a disenar politicas ? sean educativas o curriculares? en los tres ambitos para los cuales aquellas fueron elaboradas: la administracion educativa, las entidades de formacion permanente y, por ultimo, los centros educativos. Todas estas propuestas se orientan a la configuracion de escenarios que permitan mejorar, de forma significativa, los procesos de formacion permanente del profesorado; cosa que significa incidir, de manera directa, en la propia calidad de la educacion infantil.
Modulation of Mac-1 (CD11b/CD18)-Mediated Adhesion by the Leukocyte-Specific Protein 1 Is Key to Its Role in Neutrophil Polarization and Chemotaxis1

Leukocyte-specific protein 1 (LSP1) is an intracellular filamentous-actin binding protein which modulates cell motility. The cellular process in which LSP1 functions to regulate motility is not yet identified. In this study, we show that LSP1 negatively regulates fMLP-induced polarization and chemotaxis of neutrophils through its function on adhesion via specific integrins. Using LSP1-deficient (Lsp1−/−) mice, we show increased neutrophil migration into mouse knee joints during zymosan-induced acute inflammation, an inflammatory model in which the number of resident synoviocytes are not affected by LSP1-deficiency. In vitro chemotaxis experiments performed by time-lapse videomicroscopy showed that purified Lsp1−/− bone-marrow neutrophils exhibit an increased migration rate toward a gradient of fMLP as compared with wild-type neutrophils. This difference was observed when cells migrated on fibrinogen, but not fibronectin, suggesting a role for LSP1 in modulating neutrophil adhesion by specific integrins. LSP1 is also a negative regulator of fMLP-induced adhesion to fibrinogen or ICAM-1, but not to ICAM-2, VCAM-1, or fibronectin. These results suggest that LSP1 regulates the function of Mac-1 (CD11b/CD18), which binds only to fibrinogen and ICAM-1 among the substrates we tested. fMLP-induced filamentous actin polarization is also increased in the absence of LSP1 when cells were layered on fibrinogen, but not on fibronectin. Our findings suggest that the increased neutrophil recruitment in Lsp1−/− mice during acute inflammation derives from the negative regulatory role of LSP1 on neutrophil adhesion, polarization, and migration via specific integrins, such as Mac-1, which mediate neutrophil responses to chemotactic stimuli.
Multidimensional wavelet neural networks Based on polynomial powers of sigmoid: a framework to image verification

Wavelet functions have been used as the activation function in feed forward neural networks. An abundance of R&D has been produced on wavelet neural network area. Some successful algorithms and applications in wavelet neural network have been developed and reported in the literature. However, most of the aforementioned reports impose many restrictions in the classical back propagation algorithm, such as low dimensionality, tensor product of wavelets, parameters initialization, and, in general, the output is one dimensional, etc. In order to remove some of these restrictions, a family of polynomial wavelets generated from powers of sigmoid functions is presented. We described how a multidimensional wavelet neural networks based on these functions can be constructed, trained and applied in pattern recognition tasks. As examples of applications for the method proposed a framework for face verfication is presented. Keywords: Artficial neural network, Human face verification, Image processing, Pattern recognition, Polynomial powers of Sigmoid (PPS), Wavelets.
Application of Sisal, Bamboo, Coir and Jute Natural Composites in Structural Upgradation

The materials chosen for structural upgradation must, in addition to functional efficiency and increasing or improving the various properties of the structures, should fulfil some criterion, for the cause of sustainability and a better quality. For example, these materials should not pollute the environment and endanger bioreserves, should be such that they are self sustaining and promote self-reliance, should help in recycling of polluting waste into usable materials, should make use of locally available materials, utilise local skills, manpower and management systems, should benefit local economy by being income generating, should be accessible to the ordinary people and be low in monetary cost. Besides improving the strength of the structure using FRPs as the raw material, it is also necessary to make use of local materials in construction. So far the work on construction. So far the work on retrofitting of structures is confined to using of carbon, glass or aramid fibres etc, very little work is being imparted in improving structures using naturally available materials, or natural fibres. The application of composites in structural facilities is mostly concentrated on increasing the strength of the structure with the help of artificial fibres and does not address the issue of sustainability of these raw materials used for strengthening purposes. In an expanding world population and with the increase of the purchasing potentials, the need for raw materials required for structural strengthening, that would satisfy the demand on world market is rapidly growing. In times when we cannot expect the fibre reinforced polymer prices to come down, with the consumption growing day by day. Also waste disposal has become one of the major problems in modern cities. At present there are two major methods in practice to dispose wastes. One is land filling and the other is burning. First one requires more valuable land and second one pollutes the environment. So, alternate methods to dispose solid waste should be found. New materials that would be cheaper and at the same time offer equal or better properties have to be developed. We have enough natural resources and we must keep on researching on these natural resources. Development of plant fibre composites has only begun. Among the various natural fibres such as, sisal fibres, bamboo fibres, coir fibres and jute fibres are of particular interest as these composites have high impact strength besides having moderate tensile and flexural properties compared to other lignocellulosic fibres. Among the various natural fibres, sisal fibre reinforced composite, bamboo fibre reinforced composite, coir reinforced composite and jute fibre reinforced composite are of particular interest as these composites have high impact strength besides having moderate tensile and flexural properties compared to other lignocellulosic fibres. Hence encouragement should be given for the use of natural fibres such as sisal fibres, bamboo fibres, coir fibres and jute fibres which are locally available
Histologic characterization of vaginal vs. abdominal surgical wound healing in a rabbit model

We aimed to compare the histologic characteristics of vaginal vs. abdominal surgical wound healing in the rabbit. Bilateral 6 mm full‐thickness circular segments were excised from the vagina and abdominal skin in 34 New Zealand white female rabbits. Animals were euthanized on the day of and 4, 7, 10, 14, 21, 28, and 35 days after wounding, and their wounds were evaluated using a modified scoring system. The inter‐ and intraobserver agreements of the scoring system were good (weighted κ 0.63 and 0.71, respectively). A transient fibrinous crust was evident in 75% of the abdominal and in none of the vaginal wound specimens on days 4–7 after wounding (p=0.01). Acute inflammation peaked at day 4 in both the vaginal and abdominal wounds, while chronic inflammation peaked at days 4–7 and 14–21 in the abdomen and vagina, respectively. Both neovascularization and the amount of granulation tissue peaked at days 4 and 7 in the vagina and abdomen, respectively. Maturation of granulation tissue and collagen deposition increased persistently in both tissues until postwounding day 35. Reepithelialization increased after wounding, and was completed by day 14 in both tissues. The surgical wound‐healing process in both the vagina and abdomen includes transient acute and chronic inflammation, fibroblast proliferation, and neovascularization, as well as progressive maturation of granulation tissue, reepithelialization, and collagen deposition. A transient fibrinous crust forms in the abdomen but not in the vagina 4–7 days after wounding. The modified histologic scoring system described here was found to be reliable and reproducible.
Research of Nematic Liquid Crystal Broadband tunable power divider

Basing on split-ring resonator(SRR), a compact broadband power divider has been implemented. The power divider uses common inverted microstrip line, and loads DSRRs unit on microstrip line metal conduction band, and at the same time loads nematic liquid crystal on inverted microstrip lines. Using Nematic Liquid Crystal in external bias with permittivity of dielectric constant variable attributes, a c-band broadband power divider is designed. The power divider not only has the advantage of compact size, low loss and easy fabrication, but the advantage of easy integration with other circuits.
Pathogenesis of haemophilic synovitis: clinical aspects

Summary. Arthropathy remains a major cause of morbidity in patients with haemophilia. Frequent bleeding into the joints leads to joint damage with resultant contractures, joint deformities and arthritis. This in turn leads to muscle atrophy, limited physical activity, osteoporosis and disability. Even though several studies of prophylactic factor replacement for persons with severe haemophilia demonstrate improved joint function, this therapy is still not readily available to most people with haemophilia around the world and a universal treatment protocol has not been used. In this article, we discuss key issues in the treatment of severe haemophilia: the optimal timing of initiation and termination of therapy, dosing options and goals of therapy. The options for countries where prophylaxis is not readily available are also discussed. Most studies are small and not randomized making consensus treatment recommendations difficult to formulate. Randomized, clinical trials are needed to provide the answers regarding the optimal treatment of patients with severe haemophilia.
Magnetic Properties of Cobalt-Based Carbide Particles Synthesized by the Polyol Process

Single-phase Co carbide particles with the Co3C structure were obtained by the polyol process using tetraethylene glycol (TEG) solution containing polyvinylpyrrolidone (PVP). Additionally, particles with a mixture of face-centered cubic Co and hexagonal close-packed Co were precipitated in the TEG solution without PVP. The particles synthesized with PVP exhibited coercivity of about 5.7 kOe, which was larger than that of the particles synthesized without PVP. Thus, the addition of PVP to the TEG solution induces the formation of Co3C-structured Co carbide particles with large coercivity. Particles precipitated from the TEG solution with an initial molar ratio of Co:Ni = 8:2 were also identified as the single phase of the Co3C structure by X-ray diffraction measurement. In addition, it was confirmed by measurements of the extended X-ray absorption fine structure spectra that Ni atoms in the precipitated particles had a local structure similar to that of Co atoms in the single-phase particles with the Co3C structure. Thus, Ni-substituted Co carbide particles with the Co3C structure can be obtained by the polyol process using PVP.
Aptasensor for diabetes mellitus detection and monitoring

DNA aptamers against GHSA, which is protein marker for diabetes mellitus, were selected and modified. In combination properties of modified GHSA binding aptamer and fluorescence quenching of GO, we develop simple and sensitive platform for detection of GHSA in both PBS and human serum with the LOD of 50 μg/mL. We envision that our GO-aptamer platform has a potential to be GHSA detection for screening and monitoring diabetes mellitus.
The Genomedata format for storing large-scale functional genomics data

Summary: We present a format for efficient storage of multiple tracks of numeric data anchored to a genome. The format allows fast random access to hundreds of gigabytes of data, while retaining a small disk space footprint. We have also developed utilities to load data into this format. We show that retrieving data from this format is more than 2900 times faster than a naive approach using wiggle files. Availability and Implementation: Reference implementation in Python and C components available at http://noble.gs. washington.edu/proj/genomedata/ under the GNU General Public License. Contact: william-noble@uw.edu
Adherence to Central-Line Insertion Practices (CLIP) with Peripherally Inserted Central Catheters (PICC) and Central Venous Catheters (CVC): A Prospective Study of 50 Hospitals in China

To the Editor—Two types of common central venous central lines (CL), peripherally inserted central catheters (PICC) and central venous catheters (CVC), are widely applied in the care of patients with severe diseases treated in surgical, intensive care, oncological and hematological units. In addition, invasive procedure for PICC and CVC could result in central-line–associated bloodstream infections (CLABSIs), leading to significant morbidity, mortality, and cost among hospitalized patients. Strict compliance with central-line insertion practices (CLIP), including hand hygiene, proper use of a skin antiseptic prior to insertion, skin preparation agent completely dried before insertion, and application of maximal sterile barriers (MSB) during insertion, would significantly decrease the risk of subsequent CLABSIs. However, CLIP adherence in China has not been reported. In this study, we first performed a prospective multicenter study using a cell-phone app (cf, software application) to assess CLIP adherence for PICC and CVC insertions in Jiangsu Province in China from March 1 through March 31, 2017. During the study period, 12 of 13 cities (92.3%) and 50 general hospitals were included in this study. WeChat (www.Tencent.com) and contact groups were applied to train all the investigators online to achieve homogeneity. All investigators observed all PICC and CVC procedures and uploaded the data to the terminal database via an app installed in a cell phone. This study included 1,377 PICC insertions (tertiary general hospitals, 1,148 insertions, 83.4%; secondary general hospitals, 229 insertions, 16.6%) and 2,304 CVC insertions (tertiary general hospitals, 1,980 insertions, 85.9%; secondary general hospitals, 324 insertions, 14.1%). Compared to CVC insertions, adherence to hand hygiene and complete drying of the skin disinfectant before insertion were significantly greater with PICC insertions (P< .001) (Table 1). In addition, CVCs were always placed by doctors, while PICCS were mainly table 1. Survey Responses
Recalibrating the Gram Stain Diagnosis of Male Urethritis in the Era of Nucleic Acid Amplification Testing

Background: Criteria for diagnosis of male urethritis based on a Gram-stained smear (GSS) of urethral discharge were developed before the era of nucleic acid amplification testing (NAAT) for Neisseria gonorrhoeae (Ng) and Chlamydia trachomatis (Ct) and may be too stringent when considering the higher sensitivity of NAAT. Objective: To evaluate Ct and Ng positivity at different strata of polymorphonuclear cells (PMN) per high power field (hpf) GSS microscopy. Methods: A retrospective analysis of the electronic medical record system of the Denver Metro Health Clinic between March 1, 2005 and December 31, 2010; all men with a GSS test during this period had an NAAT for Ct and Ng and had GSS results recorded at 1 PMN/hpf increments. Results: A total of 13,520 GSS were available for analysis. For Ct, a statistically significant trend was observed along the PMN/hpf incremental spectrum, and a significant increase in positivity was observed between the 1 and 2 PMN/hpf strata (from 6.5% to 16.2%). For men diagnosed with Ng, no such trend was observed, and >95% of GSS results fell in the >10 strata. A subanalysis to control for laboratory technician variance and difference in NAAT technology showed similar results. Conclusion: Our data support lowering the diagnostic criteria of the GSS diagnosis of male urethritis to ≥2 PMN/hpf. At this level, the Ct positivity (16.2%) is similar or higher than positivity in men who receive presumptive chlamydia treatment as a contact to patients diagnosed with gonorrhea, pelvic inflammatory disease, or mucopurulent cervicitis.
Inductive power transmission system with stabilized output voltage using local primary-and secondary-side control

In this paper, a primary and secondary series compensated inductive power transmission system with primary-side zero phase angle control and a loss-free clamp (LFC) circuit on the secondary-side is described. The effects of non-synchronous tuning are analyzed and intendet detuning is proposed to guarantee controllability. The functional principle of the LFC circuit, which is required for output voltage stabilization over a wide load range and varying magnetic coupling, is explained. Finally, theoretical results are verified experimentally.