Miracle-dz/UniFAR-FTUs huggingface dataset:
REACT: An Interprofessional Education and Safety Program to Recognize and Manage the Compromised Obstetric Patient

In recent years, there has been an increase in the number of pregnancies complicated by preexisting medical conditions as well as an increase in maternal morbidity and mortality in the United States. The goal of the REACT quality and safety initiative was to reduce maternal morbidity and mortality by providing an interprofessional education program for recognizing and managing the woman who becomes compromised during pregnancy, childbirth, or the puerperium. REACT is an acronym for Recognize, Educate, Activate, Communicate, and Treat early signs and symptoms of maternal compromise. Early signs and symptoms of maternal compromise outlined in the REACT program are similar to recently published recommendations by the American College of Obstetricians and Gynecologists, the Centers for Disease Control and Prevention, the Society for Maternal-Fetal Medicine, the Health Resources and Services Administration, the Association of Women's Health, Obstetric and Neonatal Nurses, and the American College of Nurse-Midwives.
An Application for the Control of Stochastic Petri nets via Fluidification Approach

Petri nets are frequently used for modeling and analysis of discrete event systems. Similar to other modeling formalisms for discrete systems, it suffers from state explosion. Fluidification can be used to overcome this difficulty yielding fluid approximation of original Petri nets in the sense of behaviours and properties. This models are called continuous Petri nets. In this work, stochastic Petri nets and their fluid approximation timed continuous Petri nets is considered. One of the main advantages of timed continuous Petri nets is to be able to design a controller by using more analytical techniques. But it is important to come back to a reasonable design or control in the original discrete setting. In this work, a target state control strategy of timed continuous Petri nets will be interpreted for the control of underlying Stochastic Petri nets. The efficiency of this interpretation will be studied on a table factory system. Petri nets are frequently used for modeling and analysis of discrete event systems. Similar to other modeling formalisms for discrete systems, it suffers from state explosion. Fluidification can be used to overcome this difficulty yielding fluid approximation of original Petri nets in the sense of behaviours and properties. This models are called continuous Petri nets. In this work, stochastic Petri nets and their fluid approximation timed continuous Petri nets is considered. One of the main advantages of timed continuous Petri nets is to be able to design a controller by using more analytical techniques. But it is important to come back to a reasonable design or control in the original discrete setting. In this work, a target state control strategy of timed continuous Petri nets will be interpreted for the control of underlying Stochastic Petri nets. The efficiency of this interpretation will be studied on a table factory system.
Artificial neural network based wave complex detection in electrocardiograms

Abstract This paper describes a Predictive Neural Network (PNN) based technique to detect QRS complexes of electrocardiograms (ECGs). The PNN is trained, using the back propagation algorithm, on non-QRS portions of the ECG to predict the signal one-step ahead. High prediction error is then taken as an indication of the occurrence of a QRS complex. A simple peak detection logic is then invoked to mark the exact location and magnitude of either a Q- or an R- or an S- peak within the QRS complex. The performance of the detector software is illustrated with examples representative of different QRS morphologies. The accuracy of QRS complex detection has been tested using bipolar standard limb leads of a standard ECG library; a sensitivity of 98·96% has been achieved. A brief discussion on how well this technique performs in comparison with the other QRS detectors is also presented.
Japanese Participation in British Industry

1. Japanese Direct Investment in the UK: The General Picture Part 1 2.The Extent and Structure of Japanese Participation in UK Manufacturing Industry 3.The Reasons for Japanese Participation in UK Manufacturing Industry Part 2 4 Management and Control Structures in Japanese Affiliates 5.The Performance of Japanese Manufacturing Affiliates Part 3 6. The Impact of Japanese Manufacturing Affiliates on their UK Suppliers - Part One 7. The Impact of Japanese Manufacturing Affiliates on their UK Suppliers - Part Two 8. The Impact of Japanese Affiliates on their Competitors 9. The Impact of Japanese Affiliates on their Customers 10. Labour Related Questions 11. Some Other Features of Japanese Direct Investment in UK Manufacturing Industry 12. The Future of Japanese Participation in UK Industry
Supporting workspace awareness in groupware (video program) (abstract only)

Real-time groupware systems often let each participant control their own view into a shared workspace. However, when collaborators do not share the same view they lose their awareness about where and how others are interacting with the workspace artifacts. We have designed a number of add-on awareness windows that help people regain this awareness. Two general strategies and several variations are illustrated in this video that extend work done in a few other groupware systems. First, radar overviews shrink the entire workspace to fit within a single window. Awareness is indicated by overlaying the overview with boxes representing others' viewports, by telepointers that show where they are working, and by seeing changes to objects in the workspace as they are made. The workspace can be represented within the radar overview as a scaled miniature, by stylized objects, or by its semantic structure. Second, two types of detailed views show some or all of what another person can see, providing awareness of fine-grained details of others' actions.
Importance of both the Coding and the Segment-Specific Noncoding Regions of the Influenza A Virus NS Segment for Its Efficient Incorporation into Virions

ABSTRACT The genome of influenza A virus consists of eight single-strand negative-sense RNA segments, each comprised of a coding region and a noncoding region. The noncoding region of the NS segment is thought to provide the signal for packaging; however, we recently showed that the coding regions located at both ends of the hemagglutinin and neuraminidase segments were important for their incorporation into virions. In an effort to improve our understanding of the mechanism of influenza virus genome packaging, we sought to identify the regions of NS viral RNA (vRNA) that are required for its efficient incorporation into virions. Deletion analysis showed that the first 30 nucleotides of the 3′ coding region are critical for efficient NS vRNA incorporation and that deletion of the 3′ segment-specific noncoding region drastically reduces NS vRNA incorporation into virions. Furthermore, silent mutations in the first 30 nucleotides of the 3′ NS coding region reduced the incorporation efficiency of the NS segment and affected virus replication. These results suggested that segment-specific noncoding regions together with adjacent coding regions (especially at the 3′ end) form a structure that is required for efficient influenza A virus vRNA packaging.
Locating Burst Onsets Using SFF Envelope and Phase Information

Bursts are produced by closing the oral tract at a place of articulation and suddenly releasing the acoustic energy built-up behind the closure in the tract. The release of energy is an impulselike behavior, and it is followed by a short duration of frication. The burst release is short and mostly weak in nature (compared to sonorant sounds), thus making it difficult to detect its presence in continuous speech. This paper attempts to identify burst onsets based on parameters derived from single frequency filtering (SFF) analysis of speech signals. The SFF envelope and phase information give good spectral and temporal resolutions of certain features of the signal. Signal reconstructed from the SFF phase information is shown to be useful in locating burst onsets. Entropy and spectral distance parameters from the SFF spectral envelopes are used to refine the burst onset candidate set. The identified burst onset locations are compared with manual annotations in the TIMIT database.
Prognostic influence of increased fibrinogen and C-reactive protein levels in unstable coronary artery disease. FRISC Study Group. Fragmin during Instability in Coronary Artery Disease.

BACKGROUND The prognostic influences of fibrinogen and C-reactive protein levels and their relations to myocardial damage in unstable coronary artery syndromes have not been well described. METHODS AND RESULTS Fibrinogen and C-reactive protein were determined at inclusion and related to outcome after 5 months in 965 patients with unstable angina or non-Q-wave myocardial infarction randomized to 5 weeks with low-molecular-weight heparin or placebo. The probabilities of death were 1.6%, 4.6%, and 6.9% (P=.005) and the probabilities of death and/or myocardial infarction were 9.3%, 14.2%, and 19.1% (P=.002), respectively, in patients stratified by tertiles of fibrinogen (< 3.38, 3.38 to 3.99, and > or = 4.0 g/L). The probabilities of death were 2.2%, 3.6%, and 7.5% (P=.003) after stratification of patient data by tertiles of C-reactive protein level (< 2, 2 to 10, and > 10 mg/L). In logistic multiple regression analysis, increased fibrinogen levels were independently associated with the incidence of death and/or myocardial infarction (P=.013), and elevated C-reactive protein level was associated with the incidence of death (P=.012). The increased relative risk of subsequent death or myocardial infarction in individuals with an elevated fibrinogen level was consistent in most subgroups evaluated; although significantly so only in patients with signs of myocardial damage. CONCLUSIONS Increased levels of both fibrinogen and C-reactive protein are associated with a worse outcome in patients with unstable coronary artery disease. The increased risk associated with elevated fibrinogen levels is independent of, and additive to, the prognostic influence of myocardial damage.
Perman: Fine-Grained Permission Management for Android Applications

Third-party libraries (3PLs) are widely introduced into Android apps and they typically request permissions for their own functionalities. Current Android systems manage permissions in process (app) granularity. Hence, the host app and the 3PLs share the same permission set. 3PL-apps may therefore introduce security risks. Separating the permission sets of the 3PLs and those of the host app are critical to alleviate such security risks. In this paper, we provide Perman, a tool that allows users to manage permissions of different modules (i.e., a 3PL or the host app) of an app at runtime. Perman relies on dynamic code instrumentation to intercept permission requests, and accordingly provide a policy-based permission control. Unlike existing tools that generally require to redesign 3PL-apps, it can thus be applied to the existing apps in market. We evaluate Perman on real-world apps. The experiment results verify its effectiveness in fine-grained permission management.
A prospective study of the intake of vitamins C, E, and A and the risk of breast cancer.

BACKGROUND Although it has been hypothesized that large intakes of the antioxidant vitamins C, E, and A reduce the risk of breast cancer, few prospective data are available. METHODS We prospectively studied 89,494 women who were 34 to 59 years old in 1980 and who did not have cancer. Their intakes of vitamins C, E, and A from foods and supplements were assessed at base line and in 1984 with the use of a validated semiquantitative food-frequency questionnaire. RESULTS Breast cancer was diagnosed in 1439 women during eight years of follow-up. After multivariate adjustment for known risk factors, the relative risk among women in the highest quintile group for intake of vitamin C as compared with the risk among those in the lowest quintile group was 1.03 (95 percent confidence interval, 0.87 to 1.21); for vitamin E, after vitamin A intake had been controlled for, the relative risk was 0.99 (95 percent confidence interval, 0.83 to 1.19). In contrast, among women in the highest quintile group for intake of total vitamin A the relative risk was 0.84 (95 percent confidence interval, 0.71 to 0.98; P for trend = 0.001). Among women in the lowest quintile group for intake of vitamin A from food, consumption of vitamin A from supplements was associated with a reduced risk (P = 0.03). The significant inverse association of vitamin A intake with the risk of breast cancer was also found on study of data based on the 1984 questionnaire and four years of follow-up. CONCLUSIONS Large intakes of vitamin C or E did not protect women in our study from breast cancer. A low intake of vitamin A may increase the risk of this disease; any benefit of vitamin A supplements may be limited to women with diets low in vitamin A.
Determinants of Internet Usage in Ghanaian Hotels: The Case of the Greater Accra Region (GAR)

ABSTRACT The Internet has emerged as a very important technology among businesses. Studies indicate that regardless of the technological revolution experienced in the tourism industry, hospitality organizations have traditionally been reluctant to utilize Information Communication Technology (ICT). They are impeded by many factors in their attempt to employ the Internet. This study, therefore, sought to explore and explain the factors determining the adoption and use of the Internet, and discuss the challenges inherent in its utilization in Ghanaian hotels. The study found that, although the hotels' environmental context, managerial characteristics, and perceived attributes of the Internet all have somewhat influence on their adoption and use of the Internet; organizational characteristics were better determinants of the hotels' tendency to employ the Internet for business purposes. These hotels were impeded in their attempt to utilize the World Wide Web (www) by a number of challenges with costs and inadequate knowledge as critical factors. Additional research is necessary to reassess the results and widen the scope of this study.
Transcription of Epstein-Barr virus-encoded nuclear antigen 1 promoter Qp is repressed by transforming growth factor-beta via Smad4 binding element in human BL cells.

In Epstein-Barr virus (EBV)-infected BL cells, the oncogenic EBV-encoded nuclear antigen 1 (EBNA 1) gene is directed from the latent promoter Qp. Yeast one-hybrid screen analysis using the -50 to -37 sequence of Qp as the bait was carried out to identify transcriptional factors that may control Qp activity. Results showed that Smad4 binds the -50 to -37 sequence of Qp, indicating that this promoter is potentially regulated by TGF-beta. The association of Smad4 with Qp was further confirmed by supershift of EMSA complexes using Smad4-specific antibody. The transfection of a Qp reporter construct in two EBV(+) BL cell lines, Rael and WW2, showed that Qp activity is repressed in response to the TGF-beta treatment. This repression involves the interaction of a Smad3/Smad4 complex and the transcriptional repressor TGIF, as determined by cotransfection assay and coimmunoprecipitation analysis. Results suggest that TGF-beta may transcriptionally repress Qp through the Smad4-binding site in human BL cells.
Deployment of Innovative Genetic Vector Control Strategies: Progress on Regulatory and Biosafety Aspects, Capacity Building and Development of Best-Practice Guidance

In the ongoing fight against vectors of human diseases, disease endemic countries (DECs) may soon benefit from innova- tive control strategies involving modified insect vectors. For instance, three promising methods (viz. RIDL® (Release of Insects with a Dominant Lethal), Wolbachia infection, and refractory mosquito technology) are being developed by researchers around the world to combat Aedes aegypti, the primary mosquito vector of viral fevers such as dengue (serotypes 1-4), chikungunya and yellow fever. Some of these techniques are already being extended to other vectors such as Aedes albopictus (the secondary vector of these diseases) and Anopheles mosquito species that transmit malaria. To enable DECs to take advantage of these promising methods, initiatives are underway that relate to biosafety, risk assessment and management, and ethical-social-cultural (ESC) aspects to consider prior to and during the possible deployment of these technologies as part of an integrated vector control programme. This is a brief overview of the objectives and timelines of some of the initiatives being championed by international institutions, including the United Nations Development Programme (UNDP), the World Health Organization (WHO) and the Grand Challenges in Global Health (GCGH) initiative co-sponsored by the Bill & Melinda Gates Foundation.
Enterprise Risk Management In Private Firms: Does Ownership Structure Matter?

Private firms adopt Enterprise Risk Management (ERM) practices voluntarily. Using results of a survey that involved 78 respondents, we investigate the adoption of ERM practices in Italian private corporations and question whether ERM adoption is affected by the ownership structure of the firm. We find that agency conflicts between controlling and minority shareholders, which arise when ownership dispersion decreases, affect ERM adoption, and that when proprietorship is more dispersed, the firm places more focus on ERM projects. Additionally, we document the different roles of different types of owners. More specifically, in line with the patronage agency theory, the government-controlled enterprises undergo more intense ERM, whereas, in line with behavioral agency theory, individual and family-controlled firms pay less attention to ERM adoption.
Ambiguous Business Value Harms Software Products

Business value is something that delivers profit to the organization paying for the software in the form of an increase in revenue, an avoidance of costs, or an improvement in service. This is the dusty IRACIS (increase revenue, avoid costs, improve service) idea from Chris Gane and Trish Sarson's 1977 book Structured Systems Analysis (McDonnell Douglas Information).
1 Rac GTPase isoforms , Rac 1 and Rac 2 , play a redundant and crucial role in T-cell development Running title : Rac 1 and Rac 2 in T-cell development

Rac GTPase isoforms, Rac1 and Rac2, play a redundant and crucial role in T-cell development Running title: Rac1 and Rac2 in T-cell development Fukun Guo, Jose A. Cancelas, David Hildeman, David A. Williams and Yi Zheng* Divisions of Experimental Hematology and Cancer Biology, and Immunobiology, Children’s Hospital Medical Center, and Hoxworth Blood Center, University of Cincinnati, Cincinnati, OH 45229 Current address: Division of Hematology and Oncology, Boston Children’s Hospital, Boston, MA 02115
EEL 5091 – Introductory Quantum Mechanics for Nanodevices Final Project Proposal 7 March 2007

Overview of Strained Silicon Technology With its physical limitations already in sight, industry and academic microelectronics research has been focused on developing new technologies to extend Moore’s Law. One of these viable technologies is strained silicon. The attractiveness of strained-Si is that it increases carrier mobility, can be easily integrated into current manufacturing processes, and is a low-cost technology. As a result, there is a lot of ongoing research dedicated strained silicon technology at both the academic and industrial level. In fact, beginning with the 90nm node, Intel began to implement strained silicon technology into their microprocessors and other chipmakers have begun to follow suit.
AFM study shows prominent physical changes in elasticity and pericellular layer in human acute leukemic cells due to inadequate cell–cell communication

Biomechanical properties of single cells in vitro or ex vivo and their pericellular interfaces have recently attracted a lot of attention as a potential biophysical (and possibly prognostic) marker of various diseases and cell abnormalities. At the same time, the influence of the cell environment on the biomechanical properties of cells is not well studied. Here we use atomic force microscopy to demonstrate that cell–cell communication can have a profound effect on both cell elasticity and its pericellular coat. A human pre-B p190BCR/ABL acute lymphoblastic leukemia cell line (ALL3) was used in this study. Assuming that cell–cell communication is inversely proportional to the distance between cells, we study ALL3 cells in vitro growing at different cell densities. ALL3 cells demonstrate a clear density dependent behavior. These cells grow very well if started at a relatively high cell density (HD, >2 × 105 cells ml−1) and are poised to grow at low cell density (LD, <1 × 104 cells ml−1). Here we observe ∼6× increase in the elastic (Young’s) modulus of the cell body and ∼3.6× decrease in the pericellular brush length of LD cells compared to HD ALL3 cells. The difference observed in the elastic modulus is much larger than typically reported for pathologically transformed cells. Thus, cell–cell communication must be taken into account when studying biomechanics of cells, in particular, correlating cell phenotype and its biophysical properties.