Miracle-dz/UniFAR-FTUs huggingface dataset:
La réalité virtuelle comme nouvelle approche évaluative en neuropsychologie: l'exemple de la classe virtuelle avec des enfants ayant subi un traumatisme cranio-cérébral

Le but de cette etude etait de demontrer l'interet de la realite virtuelle en tant que nouvelle approche d'evaluation en neuropsychologie. Pour ce faire, un groupe de 8 enfants ayant subi un traumatisme cranio-cerebral a ete compare a un groupe de 6 enfants temoins, sur le rendement donne a un test traditionnel et a un test virtuel de performance continue (VIGIL CPT et CPT de la classe virtuelle). Les resultats montrent que le CPT virtuel met en lumiere des differences significatives entre les deux groupes en regard des erreurs d'inhibition et des mouvements de la tete. Par contre, aucune difference n'est soulignee entre les deux groupes avec le CPT traditionnel.
JTRS applications to DoD programs: technology and implementation

(U) This paper summarizes advancements and lessons learned in the application of the Joint Tactical Radio System (JTRS) Software Communications Architecture (SCA) to software radios, wireless networks and wideband waveforms. It provides a brief overview of the SCA and its application to emerging radio systems. It provides insight into implementation issues in the development of programmable radios and discusses applicability, above 2 GHz and at high data rates required by future networked systems. Specific areas are discussed that are critical in the development of deployable systems and include: (1) processor loads required to implement both low latency networked systems and legacy waveforms;. (2) National Security Agency (NSA) verification of a SCA-compliant radio; (3) boot-up time; (4) portability of firmware for waveforms implemented in field programmable gate arrays; and lastly (5) a waveform description language is described that is being developed to address firmware portability in SCA and non-SCA programmable radios.
The anatomy of antonymy: a corpus-driven approach

Dit proefschrift onderzoekt patroon-gebaseerde methoden om automatisch antoniemen te vinden. Antoniemen zijn woordparen zoals "arm – rijk", "dag – nacht", "open – sluiten", en andere paren die onderling een contrastrelatie uitdrukken. Drie onderzoeken omschreven verschillende typen patronen om antoniemen, die worden uitgedrukt door bijvoeglijke naamwoorden, zelfstandige naamwoorden en werkwoorden, te vinden in een collectie krantenteksten. De typen patronen verschillen in de hoeveelheid syntactische informatie die ze vereisen. Alle drie patroon-gebaseerde methoden zijn gestoeld op de aanname dat antoniemen significant vaker samen voorkomen binnen zinnen dan anders verwacht zou worden, en verder dat ze gevonden kunnen worden in specifieke binnenzinse patronen, zoals [tussen en ]. De beste resultaten werden behaald met tekstuele patronen die woordsoortinformatie bevatten, die vele antoniemen identificeerden, zowel nieuw als conventioneel. Aangezien deze methode geen zware computationele voorverwerking vereist en gemakkelijk kan worden toegepast op grote hoeveelheden data, zijn woordsoortpatronen een veelbelovende manier om antoniemen automatisch te identificeren. Tekstuele patronen, die geen syntactische informatie bevatten, vonden veel voorkomende alom bekende antoniemen. De syntactische-afhankelijkheidspatronen vonden de minste antoniemen maar, net als de woordsoortpatronen, vonden zij wel veel nieuwe paren. De automatisch gevonden antoniemen bevatten alom bekende voorbeelden als "oud – nieuw"; minder conventionele antoniemen als "nieuw – bestaand" en "oud – recent", atypische domeinspecifieke antoniemen als "wit – rood" (wijn) en contextafhankelijke paren zoals "buitenlands – Nederlands", als analoog aan "buitenlands – binnenlands" in de context van lokaal en internationaal beleid. Onze resultaten laten zien dat antoniemen veel meer verschillende paren omvatten dan eerder erkend is.
Bee/Hive: A Software Visualization Back End

Software understanding is the task of answering questions and gaining insights about software systems. In some cases it involves gathering broad-stroke information about what a system is doing; in other cases it involves understanding a particular aspect of the system; in still other cases it involves addressing very specific issues such as why was this routine called or what will happen if I change this input.
Iris Recognition System And Analysis Using Neural Networks

Biometric methods, which identify people based on physical or behavioural characteristics, are of interest because people cannot forget or lose their physical characteristics in the way that they can lose passwords or identity cards. Among these biometric methods, iris is currently considered as one of the most reliable biometrics because of its unique texture‘s random variation. It is found that this method for Iris Recognition design offers good class discriminacy. The iris recognition technique consists of iris localization, normalization, encoding and comparison.The Neural Classifier will be a feed forward network with three hidden layers and be used after normalization and feature extraction phase. Simulation results will be very promising in person identification.
Probing the CXCR6/CXCL16 Axis: Targeting Prevention of Prostate Cancer Metastasis

Prostate cancer (PCa) has been cited as the second leading cause of cancer-related death in American men and its morbidity/mortality has increased globally in recent years. The high mortality rate is closely associated with the spread of malignant cells to various tissues especially to bone. Nearly 10% of patients whose conditions are diagnosed as PCa clinically present with bone metastasis and almost all patients who die of prostate cancer have skeletal involvement. Identifying new mechanisms that control bone metastasis is of great consequence to facilitate the design of therapeutics aimed at decreasing metastatic risk and/or resulting secondary complications. We completed an interrogation of the Molecular Libraries Small Molecule Repository (MLSMR) for antagonists of the CXCR6 receptor in cell-based functional assay. Here, we report for the first time a novel potent (140 nM IC50) small molecule CXCR6 antagonist that is selective (>79 μM IC50) against CXCR5, CXCR4, CCR6 and APJ receptors. It is non-promiscuous against 23 other G protein-coupled receptors (GPCRs), showing only moderate activity against 5-HT2B and DAT at 10 μM in competitive binding assays. This probe will assist in addressing a key hypothesis that the CXCR6/CXCL16 axis significantly contributes to PCa cell metastasis, proliferation and subsequent bone invasion. A small molecule antagonist would block cancer cell trafficking; hence mediate a metastatic event and disease progression. Access to pharmacologically available small molecule antagonists will ultimately enable our targeted studies in disease relevant models and allow for a more seamless translational advancement toward clinical applications.
Souche de Lactobacillus utilisée comme agent de lutte biologique contre Pythium ultimum sur tomate

Le champignon Pythium ultimum est a l’origine de nombreux degâts dans les cultures maraicheres et ornementales (Lafontaine et al. 2007). Sa presence peut entrainer la mort du jeune plant ou un affaiblissement chronique de la plante induisant des pertes de rendement. Devant l’ampleur des degâts, de nombreuses etudes scientifiques sont consacrees a ce pathogene. En 2010, Levesque et al. publient le genome de P. ultimum dans le but de mieux elucider son mode d’action infectieux. Ils etablissent que ce champignon se distin gue des autres Oomycetes en particulier par sa production de proteines impliquees dans sa pathogenicite vis-a-vis des plantes. Cependant, aujourd’hui encore, le mode d’action de P. ultimum n’est pas entierement explicite. La biomasse et l’activite microbienne du sol constituent des atouts pour lutter contre les maladies du sol telles que celle causee par P. ultimum (Welbaum et al. 2004). Au sein de cette vie microbienne, les bacteries associees aux plantes resident dans la rhizosphere et la phyllosphere. Dans cet environnement complexe, elles sont sujettes a la competition, a l’antagonisme, au parasitisme et/ou a la predation d’autres organismes du Souche de Lactobacillus utilisee comme agent de lutte biologique contre Pythium ultimum sur tomate
Forskning om den svenska friskolereformens effekter - en litteraturöversikt

Sammanfattning Den svenska friskolereformen drevs igenom for cirka 20 ar sedan. Genomslaget av fristaende skolor har varit stort, speciellt pa gymnasieniva dar 40% av alla gymnasieskolor idag drivs av friskoleaktorer, i vissa kommuner aterfinns sa manga som 60% av elevunderlaget i friskolor. Trots att inforandet av friskolereformen i Sverige varit och till viss del fortfarande ar omdebatterat, samt att reformen i sig utgor ett skarpt avsteg fran tidigare socialdemokratiskt baserade utbildningspolitik ar forskningen gallande reformens konsekvenser tamligen begransad, i synnerhet i vissa avseenden. Syftet med foreliggande artikel ar darfor att summera och presentera tidigare forskning om den svenska friskolereformen, samt att identifiera kunskapsluckor och ge forslag pa aspekter inom omradet som sarskilt skulle behova belysas framover.
Distributed document clustering algorithms: a recent survey

Distributed data mining paradigm is an active research area due to the enormous volume of data that are to be processed from across a wide cluster of data nodes. Document clustering algorithms are widely applied in a variety of distributed environments like peer-to-peer networks, wireless sensor networks, etc. This paper entails a comprehensive review on most of the recent distributed document clustering algorithms that is ultimately making massive impacts on the technological realm. These algorithms are analysed based on few pivotal elements such as clustering quality, scale-up, speed-up and accuracy. Recent advances in technology have developed MapReduce-based distributed document clustering algorithms, which show dramatic improvements in the aforementioned analytical elements. Based on the review, intelligent discussions are presented for algorithm development and implementation.
Ocho años de experiencia con el "Método Mexicano" en la realización de trasplantes de células hematopoyéticas alogénicas

SUMMARY In the past eight years, in Mexico and in other developing countries, over 350 patients have undergone allogeneic hematopoietic stem cell transplants using a non-myeloablative conditioning regimen developed in Mexico and based on international standards. The so called “Mexican method” to conduct allogeneic stem cell transplants is endowed with certain advantages which make it affordable and in turn, available to individuals living in resource-poor countries. The best results using this method have been observed among patients with stage 1 chronic myelogenous leukemia and aplastic anemia. The less favourable results have been observed among patients with acute Iymphoblastic leukemia; mild to moderate results have been reported among patients with acute myelogenous leukemia. The “Mexican method” to conduct hematopoietic cells allografting has resulted not only in turning this method accessible to patients in developing countries, but also it has witnessed an increase in the academic activities of physicians from these countries involved in the field.
An Overview of Three Approaches to Scoring Written Essays by Computer. ERIC Digest.

It is not surprising that extended-response items, typically short essays, are now an integral part of most large-scale assessments. Extended response items provide an opportunity for students to demonstrate a wide range of skills and knowledge, including higher order thinking skills such as synthesis and analysis. Yet assessing students' writing is one of the most expensive and time-consuming activities for assessment programs. Prompts need to be designed, rubrics created, multiple raters need to be trained, and then the extended responses need to be scored, typically by multiple raters. With different people evaluating different essays, interrater reliability becomes an additional concern in the writing assessment process. Even with rigorous training, differences in the background, training, and experience of the raters can lead to subtle but important differences in grading (Blok & de Glopper, 1992, Rudner, 1992).
The Use of Tranexamic Acid in Percutaneous Nephrolithotomy. A Randomized Controlled Study (Local Experience)

Purpose: To evaluate the efficacy and safety of Tranexamic acid in reducing blood loss during PCNL. Materials and Methods: A total of 50 patients who underwent unilateral Percutaneous Nephrolithotomy from March 2017 to November 2017 were randomized into 2 equal groups; group (A) who received 1 gm (10 cc) of tranexamic acid ampule on call to surgery and group (B) who received (10 cc) normal saline. The Patients clinical data were collected and recorded in Microsoft Excel 2016 and analyzed using Statistical Package for the Social Science (SPSS) version 20 software program. Results: Fifty patients were included in the study: (33 males and 17 female). The mean age in group A patients was (48.12 ± 13.58) years, and in group B was (48.88 ± 16.17) with P value = 0.858. In group A the number of males was 16 (64%), and female was 9 (36%), and in group B male was 17 (68%) and female was 8 (34%). Mean body mass index (BMI) in group A was (28.58 ± 4.51) and in group B was (26.72 ± 3.71), with P value = 0.119 which is statistically not significant. The mean total blood loss in milliliters in group A was (73.80 ± 60.1), while in group B it was (117.24 ± 87.9) which is statistically significant with P-Value = 0.047. The mean hemoglobin drop in group A was (0.45 ± 0.35 g/dl) while in group B was (1.00 ± 0.46 g/dl), which is statistically significant with P value = 0.0001. The mean operative time was (48.4 ± 17) minute in group A, while it was (62.4 ± 15) in group B, with P-Value = 0.005, which is statistically was significant. Post-operative hematuria in group A; 20 (80%) patients had mild hematuria, 3 (12%) patients had moderate hematuria and 2 patients (8%) had no hematuria. In group B; 18 (72%) patients had mild hematuria, 6 (24%) patients had moderate hematuria and one patient (4%) had no hematuria, which is statistically not significant with P-Value = 0.487 (Table 2). One patient (4%) had intra operative bleeding in group A, in group B two patients (8%) had bleeding with P value of 0.79 which statistically not significant. Conclusion: Tranexamic acid is safe and effective drug in reducing blood loss and the rate of blood transfusion in percutaneous nephrolithotomy. It is associated with fewer intraoperative, postoperative complications and shorter operative time.
Clustered Tributaries-Deltas Architecture for Energy Efficient and Secure Wireless Sensor Network

The Sensor Networks have limitations in utilizing energies, developing energy-efficient routing protocol and secure routing protocol are important issues in Sensor Network. In the field of data management, Tributaries and Deltas(TD) which incorporates tree topology and multi-path topology effectively have been suggested to provide efficiency and robustness in data aggregation. And our research rendered hierarchical property to TD and proposed Clustering-based Tributaries-Deltas. Through this new structure, we integrated efficiency and robustness of TD structure and advantages of hierarchical Sensor Network. Clustering-based Tributaries-Deltas was proven to perform better than TD in two situations through our research. The first is when a Base Station (BS) notices received information as wrong and requests the network’s sensing data retransmission and aggregation. And the second is when the BS is mobile agent with mobility. In addition, we proposed key establishment mechanism proper for the newly proposed structure which resulted in new Sensor Network structure with improved security and energy efficiency as well. We demonstrated that the new mechanism is more energy-efficient than previous one by analyzing consumed amount of energy, and realized the mechanism on TmoteSKY sensor board using TinyOS 2.0. Through this we proved that the new mechanism could be actually utilized in network design.
Investigating the Use of Paired Programming for Teaching Data Structures and Algorithms

Incoming university students who have not previously studied computer programming often find it a challenging subject, leading to high failure rates (Williams & Upchurch, 2001). As a result, enrolment in computer science courses is declining (Carver et al., 2007), with the participation of female students being particularly affected (Werner, Hanks & McDowell, 2004). Research has suggested that the lack of a formalized structure for collaborative learning may be one of the factors responsible for students’ negative impressions of computer science (Werner et al., 2004). In this study we investigated whether the use of pair programming in labs would facilitate peer learning and enhance students’ confidence in their programming ability. The hypothesis motivating this intervention was that the more experienced programmers would transmit some of their knowledge to the weaker students and that the class as a whole would benefit from having the support of a partner to identify problem solving strategies and to resolve coding bugs. Results showed that the intervention was generally well received, although the weaker programmers were more positive about it than the stronger ones. Students that reported learning from pair programming were less likely to enjoy programming (r = -.496), less likely to enjoy labs (r = -.502), more likely to struggle with understanding lab material (r = .561) and more likely to report a lack of confidence in programming (r = -.415). Although there was no significant increase in final exam grades for male students, there was a significant 9.7% increase for female students. The most frequently reported positive feature of pair programming was that it allowed students to meet more people in the class.
Contrôle de l’autophagie lors des phases précoces de l’infection par l’adénovirus

L’adenovirus (AdV) est un virus non enveloppe a ADN double brin qui entre dans la cellule par endocytose. Dans l’endosome un desassemblage partiel de la capside permet la liberation d’une proteine interne de la capside, la proteine VI (PVI). Cette proteine code une helice amphipathique qui va permettre la rupture de l’endosome. Des travaux anterieurs du laboratoire ont montre que le transport des particules virales vers le noyau necessite la presence du motif conserve PPxY dans la PVI qui permet le recrutement d’ubiquitines ligases de la famille des Nedd4 (telles que Nedd4.1 et Nedd4.2). Il a precedemment ete montre que la rupture des membranes induite lors d’infections bacteriennes activait l’autophagie afin d’eliminer le pathogene intracellulaire via une degradation lysosomale. Nos resultats demontrent que l’AdV induit egalement l’autophagie lors de son entree dans la cellule. L’utilisation de differents AdV mutants nous a permis de demontrer que la rupture de l’endosome etait responsable de l’induction de l’autophagie. De plus nos resultats montrent que le virus sauvage est capable d’eviter sa degradation en controlant l’autophagie grâce au recrutement de la ligase Nedd4.2 via le motif PPxY de la PVI. Au contraire, un virus mutant depourvu du motif PPxY et donc incapable de recruter la Nedd4.2 est sequestre dans les vesicules autophagiques puis degrade par la fusion de ces vesicules avec les lysosomes. Ainsi le motif PPxY constitue un determinant moleculaire permettant au virus de contourner les defenses cellulaires antivirales.
Subjective and acoustical data about vocal effectiveness in occidental opera : Preliminary results

L'efficacite vocale est un sujet complexe et difficile : elle a particulierement ete etudiee d'un point de vue a la fois cognitif et subjectif. Dans cette communication, l'accent est mis sur l'efficacite vocale (optimisation) plutot que sur la productivite vocale (conversion et rendement energetiques). Le terme d'efficacite vocale est souvent considere comme synonyme de productivite glottique, qui est traditionnellement mesuree en termes purement physiques. Quoi qu'il en soit, l'efficacite vocale peut inclure des dimensions subjectives, et ceci particulierement en matiere d'execution artistique.
Imagination and the science-based aesthetic appreciation of unscenic nature

The popularity of the Grand Canyon, the Cliffs of Dover, and the Matterhorn (and the correlative unpopularity of marshes, bogs, and prairies) reveals in us a strong liking for scenic naturewe aesthetically value those parts of nature that are visually striking and that we would most expect to find captured in photographs. While an appreciation of scenic nature is not in itself bad, an overemphasis on it can lead to our not aesthetically appreciating other, unscenic parts of nature. This, in turn, has ecological (and perhaps even moral) implications, as our lack of appreciation can lead to our mistreating the unscenic. To rid us of too strong a bias for the scenic, a number of twentieth-century philosophers have suggested ways to develop an aesthetic appreciation of unscenic nature. ' While such an appreciation would presumably not focus exclusively (or even at all) on nature's visual properties, it is not obvious what else such an account would involve. One possibility is that our appreciation should be science-based; science can reveal to us heretofore overlooked properties of natural objects, providing new opportunities for aesthetic experience. Recently, however, Emily Brady has argued against this approach, claiming instead that our appreciation should arise out of imaginative activity. In what follows, I argue that these two approaches are not only not mutually exclusive, but that the imagination is most effective in helping us develop an aesthetic appreciation of unscenic nature, precisely when it employs, and is guided by, scientific knowledge.
Klinisches Verhalten oxyphiler Karzinome der Schilddrüse

Zusammenfassung Aus einem Kollektiv von 1665 Patienten mit malignen Tumoren der Schilddrüse konnten von 90 (5,4%) oxyphilen Karzinomen der Schilddrüse 55 Fälle erneut histologisch untersucht und klassifiziert werden. Risikofaktoren für das Auftreten von Metastasen und Lokalrezidiven wurden retrospektiv bestimmt. Bei 92% der Patienten wurde nach der Thyreoidektomie die Ablation mit 131J durchgeführt und der Krankheitsverlauf über durchschnittlich 6,5 a verfolgt. 12 Patienten bekamen Metastasen oder Lokalrezidive, in 9 Fällen als erneutes (spätes) Tumorwachstum mit einer mittleren Manifestationszeit von 4,7 a. Späte lokale Lymphknotenmetastasen und Lokalrezidive traten im Mittel 5,4 a, späte Fernmetastasen 2,7 a postoperativ auf. Thyreoglobulin erwies sich als zuverlässiger Tumormarker in der Nachsorge mit einer Sensitivität unter Suppression von 88% und unter endogener TSH-Stimulation von 75% (Spezifität: 98%). Für den klinischen Verlauf bedeutsame Faktoren sind lokale Tumorausbreitung (pT4 vs. pT1-3), makropathologische Wachstumsform des Tumors sowie das Patientenalter zum Zeitpunkt der Operation und nicht der absolute Tumordurchmesser und das Geschlecht. Die 5- und 10-Jahres-Überlebenswahrscheinlichkeiten betragen 95 bzw. 75%. Da bei durchschnittlich 6,5 a Nachsorge 18% des Kollektivs 4,7 a postoperativ auffällig wurden, sollten alle Patienten weit über das 5. Jahr postoperativ hinaus mindestens einmal jährlich mit Tg und Halssonographie untersucht werden.