Miracle-dz/UniFAR-FTUs huggingface dataset:
Theoretical Perspectives and Current Challenges of Outcome-Based Education Framework

Abstract Outcome-Based education is a performance-based approach for the curriculum development, a future-oriented learner-centered ‘Empowerment Paradigm’ that empowers and endorses all learners with future success. It is an influential and tempting way of restructuring and reorganizing engineering education. Washington Accord, an International accreditation convention, an independent agreement between signatory organizations to provide an external accreditation to undergraduate engineering programs. The accredited engineering programs that qualify an engineer to enter into the practice of professional engineers are equally recognized and acknowledged by other signatory countries and responsible organizations Pakistan Engineering Council (PEC) is a full signatory to the Washington Accord and a regulatory organization for the accreditation of engineering programs in Pakistan. To keep up the permanent membership status, it is the requirement of PEC to implement Outcome-Based in engineering degree awarding institutes in Pakistan. The main aim of Outcome-Based education in engineering education is to empower engineering students with the essential characteristics required to switch themselves into the engineering profession as a global and professional engineer. The focus of current research is to explore the philosophical and theoretical underpinnings of Outcome-Based education. Moreover, to unveil the current challenges in the implementation of OBE framework in engineering education.
Global volatility accounting and structural transformation

This paper examines whether the modern phase of globalization that started in the mid-1980s altered the canonical result which emphasizes that macroeconomic volatility declines with development. The application of a framework that gives due consideration to comovements and structural transformation to a near-universe sample of economies at different stages of economic development suggests the following set of results. First, with an explicit account for the roles of structural transformation and comovements, macroeconomic volatility declines during the modern phase of globalization for the Centre while it increases for the Periphery. Second, macroeconomic volatility of the Periphery declines with development only where structural transformation is ruled out—an unrealistic situation. Third, comovements are found to be quantitatively important, albeit without altering the fact that structural transformation constitutes the primary vehicle of transmissions of volatility from the Centre to the Periphery, where China emerges as the epicentre.
Value-Related Neuronal Responses in the Human Amygdala during Observational Learning

The amygdala plays an important role in many aspects of social cognition and reward learning. Here, we aimed to determine whether human amygdala neurons are involved in the computations necessary to implement learning through observation. We performed single-neuron recordings from the amygdalae of human neurosurgical patients (male and female) while they learned about the value of stimuli through observing the outcomes experienced by another agent interacting with those stimuli. We used a detailed computational modeling approach to describe patients' behavior in the task. We found a significant proportion of amygdala neurons whose activity correlated with both expected rewards for oneself and others, and in tracking outcome values received by oneself or other agents. Additionally, a population decoding analysis suggests the presence of information for both observed and experiential outcomes in the amygdala. Encoding and decoding analyses suggested observational value coding in amygdala neurons occurred in a different subset of neurons than experiential value coding. Collectively, these findings support a key role for the human amygdala in the computations underlying the capacity for learning through observation. SIGNIFICANCE STATEMENT Single-neuron studies of the human brain provide a unique window into the computational mechanisms of cognition. In this study, epilepsy patients implanted intracranially with hybrid depth electrodes performed an observational learning (OL) task. We measured single-neuron activity in the amygdala and found a representation for observational rewards as well as observational expected reward values. Additionally, distinct subsets of amygdala neurons represented self-experienced and observational values. This study provides a rare glimpse into the role of human amygdala neurons in social cognition.
Additive Statistical Leakage Analysis Using Exponential Mixture Model

Variation-aware leakage analysis becomes an essential design process as the technology node continuously shrinks. This article proposes a novel additive statistical leakage analysis method that uses exponential mixture model (EMM) to estimate the leakage distribution. Using a few leakage data for sub-blocks of an input circuit, we estimate any shape of leakage distribution regardless of new process nodes or operating conditions. Leakage distribution of an input circuit can be obtained by adding the leakage distributions of the sub-blocks. The proposed addition step sequentially adds the leakage distributions of sub-blocks that are expressed as EMMs. Before the addition step, we improve the accuracy by handling linear dependence among leakage simulation data of sub-blocks. In addition, we propose a method to reduce the number of components of an EMM to prevent exponential increase in runtime and memory during the addition process. The proposed method achieved 43.6 times improvement in goodness-of-fit of the estimated cumulative density functions compared to the best results of other analytic model-based methods.
Overview of surgical gastric cancer treatment according to the hospital volume in Croatia

Summary Gastric is considered neglected cancer in terms of stage at diagnosis and success of treatment worldwide. Early detec tion and quality of gastric cancer surgery remain the most important for successful treatment in terms of overall survival. In this paper, we focus on the overview of hospitals and volume of gastric cancer in Croatia as a possible baseline for quality assessment and implementation of existing quality guidelines. We accessed publicly available data from the Croatian Insur ance Fund for the period between 1st January 2013 to 31st December 2018. For background information on gastric cancer incidence and mortality, we used Croatian Cancer Registry data available online. We obtained both the number of resected gastric cancer in all Croatian hospitals as well as the length of stay. Data analysis discovered that there is a clear volume difference between teaching hospitals and non-teaching hospitals; only the first have sufficient volume for quality audit. This overview stresses one of the most critical points in cancer surgery, volume of surgery as a quality indicator.
Depression Level Prediction Using Deep Spatiotemporal Features and Multilayer Bi-LTSM

Depression is a serious psychiatric disorder that restricts an individuals ability to work properly in both their daily and professional lives. Usually, the diagnosis of depression often needs a thorough assessment by an expert. Recently, significant consideration has been given to automatic depression prediction for more reliable and efficient depression investigation. In this article, we propose a novel framework to estimate the depression level from video data by employing a two-stream deep spatiotemporal network. Our approach extracts spatial information using the Inception-ResNet-v2 network. In contrast, we introduce a volume local directional number (VLDN) based dynamic feature descriptor to capture facial motions. Then, the feature map obtained from the VLDN is fed into a convolutional neural network (CNN) to obtain more discriminative features. Additionally, we designed a multilayer bidirectional long short-term memory (Bi-LSTM) model to obtain temporal information by integrating the temporal median pooling (TMP) approach into the model. The TMP approach is employed on the temporal fragments of spatial and temporal features. Finally, extensive experimental analysis of two challenging datasets, AVEC2013 and AVEC2014, demonstrates that the proposed approach shows promising performance compared to the existing approaches for depression level prediction.
PERBEDAAN TINGKAT PENGETAHUAN DAN SIKAP IBU HAMIL SEBELUM DAN SETELAH PENYULUHAN MENGENAI INISIASI MENYUSU DINI

Latar belakang : Angka cakupan ASI eksklusif di Kota Semarang masih kurang dari target nasional 80%. Hal ini disebabkan masih rendahnya pengetahuan ibu hamil mengenai inisiasi menyusu dini (IMD) yang berdampak pada sikap ibu hamil dalam memberian ASI sedini mungkin kepada bayinya. Fakta menunjukan bahwa memberikan ASI dalam satu jam pertama atau IMD dapat meningkatkan angka cakupan ASI eksklusif. Salah satu upaya penanggulangan masalah ini adalah dengan dilakukan penyuluhan. Tujuan : Mengetahui perbedaan tingkat pengetahuan dan sikap ibu hamil sebelum dan setelah penyuluhan mengenai inisiasi menyusu dini. Metode : Penelitian ini menggunakan rancangan quasi experimental one group pretest-posttest design. Sampel berdasarkan ibu hamil berusia 20-35 tahun yang memeriksakan kehamilan di Puskesmas Halmahera dan Puskesmas Ngesrep Semarang pada bulan April-Mei 2016 yang diambil secara consecutive sampling dan didapatkan jumlah sampel sebanyak 32 ibu hamil. Subjek diberi kuesioner pretest dilanjutkan dengan penyuluhan dan kemudian diberi kuesioner posttest. Analisis data untuk tingkat pengetahuan dilakukan dengan menggunakan uji Wilcoxon, sedangkan untuk sikap dilakukan dengan uji Paired T-test. Hasil : Adanya perbedaan yang signifikan terhadap pengetahuan dan sikap ibu hamil mengenai IMD sebelum dan setelah penyuluhan dengan p<0,001. Kesimpulan : Terdapat peningkatan pengetahuan dan sikap ibu hamil mengenai IMD setelah dilakukan penyuluhan.
Fotoreticolazione di elettroliti polimerici acquosi per dye-sensitized solar cells = UV-curing of aqueous polymeric electrolytes for dye-sensitized solar cells

Per far fronte al problema legato alla questione energetica del Ventunesimo secolo, dovuto all'utilizzo massivo di combustibili fossili, la ricerca si sta volgendo verso forme di energia rinnovabili e competitive dal punto di vista economico. Le celle fotovoltaiche sono molto promettemti, in particolare quelle di terza generazione, le celle sensitizzate a colorante (dye-sensitized solar cells). Sfruttano l'assorbi,ento di fotoni da parte di un colorante, che cede elettroni all'anodo affinche questi ultimi vengano trasportati in un circuito esterno fino al catodo. La neutralita del circuito e garantita da un elettrolita. La limitaziine del mezzo elettrolitico consiste nel fatto che le celle impiegano solventi organici tossici volatili e infiammabili. Inoltre subiscono avvelenamento da parte dell'acqua e umidita esterne. Questo lavoro di tesi e incentrato sullo studio di elettroliti polimerici quasi solidi a base acquosa, per ovviare al problema della volatilita e tossicita. Grazie a diversi fipi di caratterizzazione delle membrane polimeriche, e stato possibile analizzare il comportamento delle celle assemblate sotto illuminazione e trovare il sistema piu performante.
Cerebellar Purkinje cell activity modulates aggressive behavior

Although the cerebellum is traditionally associated with balance and motor function, it also plays wider roles in affective and cognitive behaviors. Evidence suggests that the cerebellar vermis may regulate aggressive behavior, though the cerebellar circuits and patterns of activity that influence aggression remain unclear. We used optogenetic methods to bidirectionally modulate the activity of spatially-delineated cerebellar Purkinje cells to evaluate the impact on aggression in mice. Increasing Purkinje cell activity in the vermis significantly reduced the frequency of attacks in a resident-intruder assay. Reduced aggression was not a consequence of impaired motor function, because optogenetic stimulation did not alter motor performance. In complementary experiments, optogenetic inhibition of Purkinje cells in the vermis increased the frequency of attacks. These results establish Purkinje cell activity in the cerebellar vermis regulates aggression, and further support the importance of the cerebellum in driving affective behaviors that could contribute to neurological disorders.
Evaluation of knowledge, perception, attitudes, and practices of pain management of children among pediatric nursing personnel of a tertiary care hospital

Background: Pain is one of the most misunderstood, under diagnosed and under treated medical problems, particularly in children. If left unaddressed, pain can affect children in ways that will follow them throughout their lives. Nurses play an important role in assessing and managing pain among children during hospitalization. Objective: To evaluate the knowledge, attitude, and practices of pediatric pain management among nursing personnel working in pediatric tertiary care hospital. Materials and Methods: A cross-sectional, self-administered questionnaire-based survey was carried out involving 40 nurses. The questionnaire had 45 items in the domains of personal information, knowledge, and perception toward the pain of pediatric patients, and practices for pain relief. Voluntary participation was ensured and anonymity maintained at all level. Results: The mean age of nurses was 25.53 ± 4.05 years. 90% had a diploma in nursing and 10% were graduates. More than a half (57.5%) of the subjects had experience between 1 and 5 years. The mean score for knowledge was found to be 10.88 ± 2.81 (range 3-16.87%). Most of the participants (87%) thought that children have good pain sensitivity. Only 40% nurses knew about pain scoring system; however, none used pain scoring system in daily practice. None of the nurses were able to answer about the route of administration of morphine for chronic and prolonged pain. Only 44% had shown the correct attitude toward pain in children and 60% participants gave a satisfactory answer regarding practices. Conclusion: Study revealed a deficiency in the knowledge of nurses and their practices regarding pain in children.
Morphological characterization and selection of castor bean accessions for mechanized production1

ABSTRACT Castor bean (Ricinus communis L.) is an oilseed found in different regions worldwide, due to its easy propagation and adaptability. Cropping more productive disease-resistant genotypes that enable a mechanized production ensures greater economic returns for farmers. This study aimed to morphologically characterize and select promising castor bean accessions for mechanized cropping, mainly as a source of genetic variability for breeding programs with this purpose. Fifty accessions were assessed. Analysis of variance, dissimilarity clustering via the unweighted pair-group method with arithmetic mean (UPGMA) and principal component analysis were used to analyze the collected data. The dissimilarity analysis based on the Gower distance for qualitative and quantitative variables revealed three groups of accessions and the principal component analysis enabled the selection of those with desirable traits. The accessions BOC1, PRAT1 and SM2 exhibited morpho-agronomic characteristics of interest to the mechanized production, such as ideal plant height, diameter, seed weight and oil content. Such genotypes show a potential for use as genitors in genetic breeding programs of castor bean.
A Prognostic Scoring System for Unclassifiable MDS and MDS/MPN

Abstract 1701 Patients with features of MDS and MDS/MPN who do not fulfill diagnostic criteria for a specific subtype of MDS and MDS/MPN are categorized by the WHO 2008 diagnostic criteria as MDS-U and MDS/MPN-U. MDS includes RCUD, RCMD, RARS, RAEB-1, RAEB-2, MDS-U and 5q- syndrome while MDS/MPN includes CMML, JMML, atypical CML and MDS/MPN-U. The natural history of patients who belong to these disease subtypes are hetergeneous. Although included in currently accepted prognostic scoring schemes like the International Prognostic Scoring System (IPSS) in MDS, Revised IPSS, and MD Anderson prognostic scoring schemes, they represent a minority of patients in the cohort. Within MDS/MPN cases, the clinical heterogeneity of diseases that belong to this group has been recognized and has led to the development of the MD Anderson prognostic Scoring System for CMML. Similarly, a prognostic scoring system for JMML has also been devised to help in risk stratification and treatment decisions. However, there are no prognostic scoring systems for unclassified cases of MDS and MDS/MPN. Clinically, we observe stark differences in treatment responses and clinical outcomes between MDS/MPN-U and other MDS/MPN-subtypes, and MDS-U with other subtypes of MDS. In total, we studied 92 patients with unclassifiable cases seen at the Cleveland Clinic, including MDS/MPN-U (n=52 [57%]) and MDS-U (n=40 [43%]). Hematologic, bone marrow (BM), cytogenetic (metaphase cytogenetic [MC]/SNP-A) and survival data were collected. Survival comparisons were made by Kaplan-Meier analyses. Cox-proportional hazard ratio was used to determine factors predictive of outcomes. A p-value of ≤0.05 was considered statistically significant. In this cohort, median age at diagnosis was 69 years (20–88), 65% (60/92) were male, and 35% (32/92) were female. Median follow-up was 21 months. Median absolute neutrophil count (ANC) was 2.69k/uL (0–87), peripheral blood (PB) blasts 0% (0–70%), hemoglobin 9.6g/dL (5–15), and LDH 260 U/L (105–2113). SNP-A karyotyping was completed for 65 patients, and new cytogenetic mutations were detected in 72% (47/65): (gains [64%], losses [57%], UPDs [25%]). In 52% (49/92) of patients, we sequenced molecular mutations that typically confer poor prognosis in myeloid neoplasms, such as ASXL1, IDH1/2, EZH2, K/NRAS, CBL and TP53. This sequencing revealed a mutational frequency of 18% (9/49) in TET2, 14% (7/49) in ASXL1, 6% (3/49) in EZH2 exons 18–19, 2% (1/49) in CBL, 2% (1/49) in NRAS, and 4% (2/49) in TP53. No mutations were found in IDH1/2 and KRAS. In univariate analysis of clinciopathologic factors, the following factors were found to be associated with overall survival: ANC (≥8.5 vs 3% v. ≤3%) (p 3.6g/dL) (p 11.5g/dL) (p 85 vs ≤85%) (p Disclosures: No relevant conflicts of interest to declare.
On being a doctor in an acute NHS hospital trust: a classic grounded theory

ion. In qualitative research studies data from different sources are triangulated to minimise researcher bias and establish the credibility of the quality of the data (Bowen, 2009). Researcher bias is not a concern in classic GT because the methodology of constant comparison and theoretical sampling significantly reduces bias and the emerging theory transcends time, person and place (Glaser, 1998). Triangulation, in this study was not for confirmation but richness. Constant comparison, theoretical sampling and memoing ensured that if data from any of the three sources were relevant then it would earn its place in the emerging theory.
The impact of mission-oriented R&D on domestic and foreign private and public R&D, total factor productivity and GDP

We analyse the dynamic interaction of mission-oriented R&D expenditure stocks with domestic and foreign private and public R&D, total-factor-productivity (TFP) and gross domestic product (GDP) for seven EU countries, for which we have sufficiently long time-series of mission-oriented R&D data. We use the vector-error-correction (VECM) method. Permanent shocks on mission-oriented R&D increase total-factor-productivity and GDP, mostly because for the UK private R&D is increased or, for Belgium and Italy, public R&D is increased or, for Denmark, France, Germany and the Netherlands, both are increased. France has an initial phase where mission-oriented R&D has to be reduced first and expanded later to get good policy results. On average across periods and countries, a 1 percent increase of mission-oriented R&D leads to an additional 0.485% public R&D, 0.705% private R&D, 48.5% for TFP, and 0.56% GDP. We also show years of positive gains, the sums of discounted net present values, and the average yearly gains/GDP ratio. Mission-oriented R&D has high internal rates of return calculated from comparison of baseline and shock scenario comparison using VECM simulations until 2040. Heterogeneity limits the possibility to find a common model of long-term relations. For most countries we find that in steady states mission R&D reacts to foreign and domestic public R&D and increases TFP. TFP, foreign public and domestic private R&D have two-way causality relations.
Treatment of Autoimmune Haemolytic Anaemia with Hepatitis C Virus-A Real Challenge

Hepatitis C virus (HCV) infection is a potentially curable disease. The first line of treatment is pegylated interferon and ribavirin, both of which cause haemolysis. HCV itself causes autoimmune haemolytic anaemia (AIHA). Treatment of AIHA with steroid is contraindicated in patients on interferon. We report the successful treatment of a patient with AIHA infected with HCV whose treatment was a real challenge due to the risk of exacerbation of haemolysis by antiviral treatment. We describe the successful treatment of this patient initially with corticosteroids followed by pegylated interferon and gradual increase of the dose of ribavirin
Development of Caring Information Service App for Dementia Patient’s Family

경제협력개발기구(Organization for Economic Co-operation and Development, OECD) 보고서에 따르면 우리나라는 고령화 속도가 가 장 빠르게 진행되는 나라로[1], 국내 치매 환자 수 또한 2015년 65만 명 에서 2018년 10만 명이 증가한 75만 명이 넘는 것으로 추산하고 있다 [2]. 이것은 65세 이상 인구 중 치매환자 비율이 2015년 9.8%에서 10.16%, 2050년에 15.1%로 증가할 것이고, 노인 7명 가운데 1명꼴로 치 매환자가 되는 셈이다. 치매 유병률 증가로 국내 치매관리비가 2015년 약 13조 2,000억 원에서 2050년 16조 5,000억 원까지 늘어나 치매관련 경제적 부담도 지속적으로 커질 것으로 전망하고 있다[2]. 세계보건기 치매환자가족을 위한 돌봄 교육 서비스 앱 개발
Using G-652 Optical Fiber to Control Mountain Massifes of Coal Mines

ray of coal mines, which is very promising in terms of creating a distributed monitoring system ca-pable of timely signaling to personnel about the danger of a sudden collapse of a mine. Materials and methods. To develop methods for monitoring and measuring the geotechnical parameters of the workings, a simulation laboratory bench based on fiber-optic sensors was developed. The authors used a quartz single-mode optical fiber 9/125 μm (OS2) Corning SMF-28e + ®. The article proposes systems in two variants, depending on the tasks and functionality. In the first variant, the well-known method of optical reflectometry OTDR (Optical time domain reflectometer) is used. In the second variant, the values of the additional losses caused by the mechanical action on the optical fiber are controlled. Results. During mechanical action on an optical fiber microcracks occur, leading to a change in the properties of light and an increase in additional losses of the light wave passing through it. Conclusion. The use of ITU-T G.652. D standard optical fiber for monitoring the geomechanical state of an array of coal mine workings is very promising, since the VODs deve-loped on its basis have sufficiently high accuracy, measurement speed and good linearity of charac-teristics.