Miracle-dz/UniFAR-FTUs huggingface dataset:
K-anonymity against neighborhood attacks in weighted social networks

Nowadays, with the advance of Internet technology, social network is getting popular, which combines the virtual network and the real world. People employ this network to communicate with all social things of their interest, including shopping, making friends, sharing experiences of life, and so on. In social networks, the social data expands rapidly and the malicious users can easily get the social data. With the social information, they could conjecture the relationship among social network data via the systematical analysis tool. Hence, the personal privacy data in social network may be exposed to some unknown risks, and recently, these issues arising in such a network catch much attention. The protection of personal privacy social data becomes an important and urgent research in social networks. One of personal privacy social information is the relations between the individuals and their social groups, namely human relationships.
Electronic Momentary Assessment in Chronic Pain I: Psychological Pain Responses as Predictors of Pain Intensity

Objectives and Methods:Electronic momentary assessment was employed to substantiate the relevance of psychological functioning in chronic pain. More than 7100 electronic diaries from 80 patients with varying IASP classified types of chronic pain served to investigate to what extent fear-avoidance, cognitive and spousal solicitous and punishing pain responses explained fluctuations in pain intensity and whether patients with pre-chronic, recently chronic and persistently chronic pain differed in this regard. Results:Psychological pain responses explained 40% of the total variance in pain intensity: almost 24% concerned pain variance that occurred between the CPD patients and 16% pertained to pain variance due to momentary differences within these patients. Separately tested fear-avoidance and cognitive responses each explained about 28% of the total pain variance, while spousal responses explained 9%. Catastrophizing emerged as the strongest pain predictor, followed by pain-related fear and bodily vigilance. Results did not differ with the duration of chronicity. Discussion:Exaggerated negative interpretations of pain, and fear that movement will induce or increase pain strongly predicted CPD pain intensity. Spousal responses-assessed only when the spouse was with the patient who at that moment was in actual pain-may more strongly affect immobility due to pain than pain intensity per se (see part II of the study). The findings substantiate the importance of catastrophizing, fear and vigilance identified primarily in low back pain and extend this to other forms of chronic pain. The compelling evidence of momentary within-patients differences underscores that these must be accounted for in chronic pain research and practice.
tRNA insulator function: Insight into inheritance of transcription states?

DNA in eukaryotes is invariably present as a complex with histone and non-histone proteins called chromatin. These proteins play an important role in the proper regulation of genes during development and differentiation. Transcription factors and the covalent modifications of DNA, histone and non-histone proteins establish an epigenetic state that is heritable and which does not involve a change in genotype. The heritability of transcription states through cell division brings up specific questions: How are epigenetic marks established and reestablished in the daughter cells following DNA replication and mitosis? In this article we explore what is known of the cell cycle dependence of epigenetic inheritance with particular emphasis on yeast loci and discuss the role of specific proteins responsible for the establishment and maintenance of these states.
The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans

The correct wiring of neuronal circuits depends on outgrowth and guidance of neuronal processes during development. In the past two decades, great progress has been made in understanding the molecular basis of axon outgrowth and guidance. Genetic analysis in Caenorhabditis elegans has played a key role in elucidating conserved pathways regulating axon guidance, including Netrin signaling, the slit Slit/Robo pathway, Wnt signaling, and others. Axon guidance factors were first identified by screens for mutations affecting animal behavior, and by direct visual screens for axon guidance defects. Genetic analysis of these pathways has revealed the complex and combinatorial nature of guidance cues, and has delineated how cues guide growth cones via receptor activity and cytoskeletal rearrangement. Several axon guidance pathways also affect directed migrations of non-neuronal cells in C. elegans, with implications for normal and pathological cell migrations in situations such as tumor metastasis. The small number of neurons and highly stereotyped axonal architecture of the C. elegans nervous system allow analysis of axon guidance at the level of single identified axons, and permit in vivo tests of prevailing models of axon guidance. C. elegans axons also have a robust capacity to undergo regenerative regrowth after precise laser injury (axotomy). Although such axon regrowth shares some similarities with developmental axon outgrowth, screens for regrowth mutants have revealed regeneration-specific pathways and factors that were not identified in developmental screens. Several areas remain poorly understood, including how major axon tracts are formed in the embryo, and the function of axon regeneration in the natural environment.
Blog Spam: A Review

Blogs are becoming an increasingly popular target for spammers. The existence of multiple vectors for spam injection, the potential of reaching many eyeballs with a single spam, and limited deployment of anti-spam technologies has led to a sustained increase in the volume and sophistication of attacks. This paper reviews the current state of spam in the blogosphere at large and in particular as seen at TypePad, a major hosted blog service. Furthermore the effectiveness of two popular open-source email antispam programs at classifying blog comment spam is evaluated.
Differential interaction of cisplatin with the HIV-1 long terminal repeat in a resistant ovarian carcinoma cell line

We constructed a recombinant plasmid, pBHIV1, carrying the long terminal repeat (LTR) sequences of HIV-1 linked to the reporter chloramphenicol acetyl transferase (CAT) gene and to the aminoglycoside phosphotransferase (aph) gene as a selectable marker. We have introduced pBHIV1 in a human ovarian cancer cell line A2780 and in a cisplatin resistant variant 2780CP, and obtained stable geneticin resistant A27HIV1-1 and 27CPHIV1-1 cells, respectively. Both transfectant cells express CAT activity from the HIV LTR promoter. The response to the anti-neoplastic drug cisplatin was studied on the LTR regulated CAT activity in both cell lines. It was found that cisplatin at 2.5 × 10−5 M concentration stimulates the expression of CAT by 26-fold from the HIV LTR in A27HIV1-1, but requires a concentration of 5 × 10−5 M to enhance expression by 4.1-fold in the cisplatin resistant 27CPHIV1-1 cells. Carboplatin, over a range of concentrations (1 × 10−6 to 1 × 10−4 M), does not stimulate expression of CAT from the HIV-1 LTR in either of the transfected cells.
Experimental comparison between an “information based” MPPT algorithm and standard P&O in both partial shading and uniform illumination

In this paper a maximum power point tracking algorithm able to drive the operating point of a partially shaded photovoltaic system toward the global maximum power point is analyzed. The algorithm exploits detailed information about the electrical parameters of all solar panels forming the solar system gained by means of a distributed sensor network, which monitors the operation of the solar field at a very high granularity level. Data collected by the monitoring system are exploited to reconstruct the power voltage curve of the photovoltaic system, thus recognizing the presence of multiple local maxima and their exact voltage position. Experiments performed on a pilot solar filed equipped with the sensor network evidence the reliability of the analyzed approach. A convergence time of about 2.5 s was achieved independently of illumination conditions and, in case of partial shadowing, an increment of 90 W (50% more) with respect to a standard tracking algorithm.
Using 31-Bit Prefixes on IPv4 Point-to-Point Links

With ever-increasing pressure to conserve IP address space on the Internet, it makes sense to consider where relatively minor changes can be made to fielded practice to improve numbering efficiency. One such change, proposed by this document, is to halve the amount of address space assigned to point-to-point links (common throughout the Internet infrastructure) by allowing the use of 31-bit subnet masks in a very limited way.
Tree-width in Algebraic Complexity

The paper surveys some of the author's work studying the algorithmic importance of the tree-width notion in algebraic frameworks. Two approaches are described. The first gives an algorithmicmeta-theoremfor certain logically characterized propertieswithin the Blum-Shub-Smale BSS model of computation over the reals. The second reports on recent joint work with P. Koiran relating Boolean complexity and Valiant's approach to study families of polynomial systems over infinite fields and their complexity. We define particular families of polynomials via bounding the tree-width of suitably attached graphs and study the expressive power of the resulting families. The work described here is partially co-authoredwith and partially verymuch influenced by previous work of Janos A. Makowsky.
Endothelial Receptor a Blockade Alters the Hemodynamic Response to Nitric Oxide Inhibition in the Rat

Abstract : We have examined the extent to which the systemic and renal vasoconstriction induced by nitric oxide (NO) inhibition in vivo are mediated by endothelin (ET). We examined the effects of BQ610, a specific ET-A receptor antagonist, following NO inhibition with L-NAME in the anesthetized rat. Mean arterial pressure (MAP) increased following L-NAME infusion from 107 +/- 2 to 133 +/- 3 mmHg (p < 0.05 vs baseline period) and then fell to 115 +/- 3 mmHg following administration of BQ610 (p < 0.05 vs L-NAME and baseline periods). Systemic vascular resistance (SVR) increased from 1.26 +/- 0.06 to 2.17 +/- 0.18 mmHg/ml/min/300g following L-NAME (p < 0.05 vs. baseline period) and then fell to 1.69 +/- 0.12 mmHg/ml/min/300g after BQ610 (p < 0.05 vs L-NAME and baseline periods). The increase in renal vascular resistance (RVR) from 6.4 +/- 0.4 to 13.7 +/- 1.4 mmHg/ml/min/300g induced by L-NAME (p < 0.05 vs. baseline period) was reduced to 11.1 +/- 1.0 mmHg/ml/min/300g by BQ610 (p < 0.05 vs L-NAME and baseline periods). The extent to which BQ610 reversed the L-NAME induced increases in RVR and SVR was comparable (RVR by 40 +/- 9%; SVR by 52 +/- 7%). GFR and renal blood flow (RBF) were both reduced by L-NAME, but neither value increased following BQ610, possibly because the renal vasodilation induced by ET-A blockade was offset by the concomitant reduction in MAP and renal perfusion pressure. In summary, ET, acting via the ET-A receptor, partially contributes to the systemic and renal hemodynamic vasoconstrictor and hypertensive effects of NO inhibition.
Biosynthesis of N-Acetylneuraminic Acid in Cells Lacking UDP-N-Acetylglucosamine 2-Epimerase/ N-Acetylmannosamine Kinase

Abstract The first two steps in mammalian biosynthesis of Nacetylneuraminic acid, an important carbohydrate moiety in biological recognition systems, are performed by the bifunctional enzyme UDPNacetylglucosamine 2-epimerase/Nacetylmannosamine kinase. A subclone of the human B lymphoma cell line BJAB K20, lacking UDPNacetylglucosamine 2- epimerase/Nacetylmannosamine kinase mRNA as well as epimerase activity, displayed hyposialylated, functionally impaired cell surface glycoconjugates. Here we show that this cell line surprisingly still retains Nacetylmannosamine kinase activity. A gel filtration analysis of BJAB K88 control cells, which express UDPNacetylglucosamine 2-epimerase/Nacetylmannosamine kinase, revealed two Nacetylmannosamine kinase activity peaks, one coeluting with UDPNacetylglucosamine 2-epimerase activity and one coeluting with Nacetylglucosamine kinase. For this enzyme previous studies already showed ManNAc kinase activity in vitro. In contrast, the hyposialylated BJAB K20 subclone displayed only the Nacetylmannosamine kinase peak, comigrating with Nacetylglucosamine kinase. The CMPNacetylneuraminic acid content of both K88 and K20 cells and the sialylation of cell surface glycoconjugates of K20 cells could be significantly increased by supple menting the medium with Nacetylmannosamine. This Nacetylmannosamineinduced increase was drastically reduced by cosupplementation with Nacetylglucosamine only in K20 cells. We therefore propose the phosphorylation of Nacetylmannosamine as a hitherto unrecognized role of Nacetylglucosamine kinase in living cells.
Switched coupled-inductor Z-source inverters with large conversion ratio and soft-switching condition

This paper presents the concept of using a switched coupled-inductor cell for implementing quasi-Z-source inverters. By replacing one of original inductors found in the classical impedance network by a coupled-inductor, and adding one diode, new single-stage buck-boost inverter with a small count of elements and a high conversion ratio are obtained. The output voltage of the new inverter can be adjusted freely by varying the turn ratio of the coupled-inductor and the inverter shoot-through duration. The additional diode helps to circulate the leakage inductance energy to the load in a non-oscillatory manner. The transistors of the inverter turn on/off with soft-switching. The diodes turn on with zero-voltage switching and turn off with zero-current switching, their reverse-recovery problem is alleviated. The principle of the proposed converter, analysis of operation, and design guideline are included. Experimental results of the 1kW switched coupled-inductor quasi-Z-source inverter prototype are given for hardware verification. The theoretical analysis and simulation agrees well with experimental results.
Low‐Temperature In Situ Large‐Strain Plasticity of Silicon Nanowires

mentally. In this report, we present in situ TEM observation of the elastic-plastic-fracture processes of a single Si NW recorded at atomic resolution. The study directly shows the strain-induced structural evolution process of Si NWs and its largestrain plasticity (LSP). Our results indicate that the LSP of Si NWs via a brittle-ductile transition originates from a dislocation-initiated amorphization. This behavior is in contrast to the mechanical behavior of bulk Si. Our observation reveals a phenomenon and mechanism of the Si NW mechanics and is fundamentally important for Si-NW-based nanotechnology. The in situ Si NW elastic, elastic-plastic, and plastic deformation investigations were carried out by ultrahigh-resolution TEM (UHRTEM) by axially extending the Si NWs by means of a mechanical force created by a TEM specimen-supporting grid under electron beam irradiation, as reported in detail elsewhere [17,18] (also see the Experimental section and Sup
Dynamics of vortex-antivortex pairs in ferromagnets

We study the dynamics of vortex-antivortex (VA) pairs in an infinitely thin ferromagnetic film with easy-plane anisotropy. These are localized excitations with finite energy that are characterized by a topological (skyrmion) number N = 0,+1,-1. Topologically trivial (N=0) VA pairs undergo Kelvin motion analogous to that encountered in fluid dynamics. In contrast, topologically nontrivial (N = +1,-1) VA pairs perform rotational motion around a fixed guiding center. We present the results of a detailed study in both cases and further demonstrate that in the presence of dissipation a rotating N = +1,-1 VA pair shrinks to a point and is annihilated, due to the discreteness of the lattice, thus leading to a "topologically forbidden" (Delta N = 1) process. We argue that the latter process underlies the experimentally observed vortex core switching whereby the polarity of a single vortex is reversed after collision with an N = 0 VA pair created by a burst of an applied alternating magnetic field.
Beck's cognitive theory of depression: a test of the diathesis-stress and causal mediation components.

OBJECTIVES This prospective study tested the diathesis-stress and causal mediation components of Beck's (1967, 1983) cognitive theory of depression. DESIGN In order to allow for a stringent test of the aetiological component of Beck's theory, we used a short-term longitudinal design in which participants' dysfunctional attitudes were assessed prior to the occurrence of a negative event. METHODS In all, 136 high school seniors applying to the University of Pennsylvania completed measures of depressed mood and dysfunctional attitudes 1-8 weeks before receiving their admissions decision (Time 1). The assessment of dysfunctional attitudes was preceded by a priming task designed to activate latent depressogenic schemata. Participants also completed measures of depressed mood, negative views of the self, and negative views of the future shortly after they received their admissions decision (Time 2) and four days later (Time 3). RESULTS Consistent with the diathesis-stress component of Beck's theory, dysfunctional attitudes predicted increases in depressed mood immediately following a negative admissions outcome (Time 2). In addition, consistent with the causal mediation component of the theory, in negative outcome students, the relationship between dysfunctional attitudes and increases in depressed mood was mediated by negative views of the future. Contrary to predictions, however, this relationship was not mediated by negative views of the self. In addition, contrary to predictions, dysfunctional attitudes did not predict enduring depressed mood after a negative outcome (Time 3). CONCLUSIONS Individuals with dysfunctional attitudes are likely to show increases in depressed mood following the occurrence of negative events. The relationship between dysfunctional attitudes and increases in depressed mood following the occurrence of negative events is mediated by negative views of the future.
Quinine induced photosensitivity: clinical and experimental studies

Quinine induced photosensitivity, an infrequently described adverse effect, is reported in four patients. The clinical presentation and distribution was that of a light exposed site eruption characterized by oedema and erythema in three patients, and by lichen planus in the fourth. Monochromator phototesting demonstrated abnormal delayed erythema responses in the UVB, UVA and visible wavebands. The clinical features suggested a phototoxic effect but laboratory studies indicated that the molecular mechanisms involved are unusual.
The use of a new honey dressing on an infected diabetic foot ulcer

The blister on the right heel had become infected. Due to the abdominal operation the patient was weak and had a poor appetite. Finding a dressing that provides an optimal wound healing environment for the patient and is also cost-effective can be a difficult process (Baranoski, 2008). This is particularly true for hardto-heal wounds, which are associated with long duration and a high incidence of complications, often resulting in considerable quality of life and financial burdens (Romanelli et al, 2008).
Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group.

BACKGROUND Chronic inflammation is believed to increase the risk of coronary events by making atherosclerotic plaques in coronary vessels prone to rupture. We examined blood constituents potentially affected by inflammation as predictors of risk in men with hypercholesterolemia who were enrolled in the West of Scotland Coronary Prevention Study, a trial that evaluated the value of pravastatin in the prevention of coronary events. METHODS A total of 580 men who had had a coronary event (nonfatal myocardial infarction, death from coronary heart disease, or a revascularization procedure) were each matched for age and smoking status with 2 control subjects (total, 1160) from the same cohort who had not had a coronary event. Lipoprotein-associated phospholipase A2, C-reactive protein, and fibrinogen levels, and the white-cell count were measured at base line, along with other traditional risk factors. The association of these variables with the risk of coronary events was tested in regression models and by dividing the range of values according to quintiles. RESULTS Levels of C-reactive protein, the white-cell count, and fibrinogen levels were strong predictors of the risk of coronary events; the risk in the highest quintile of the study cohort for each variable was approximately twice that in the lowest quintile. However, the association of these variables with risk was markedly attenuated when age, systolic blood pressure, and lipoprotein levels were included in multivariate models. Levels of lipoprotein-associated phospholipase A2 (platelet-activating factor acetylhydrolase), the expression of which is regulated by mediators of inflammation, had a strong, positive association with risk that was not confounded by other factors. It was associated with almost a doubling of the risk in the highest quintile as compared with the lowest quintile. CONCLUSIONS Inflammatory markers are predictors of the risk of coronary events, but their predictive ability is attenuated by associations with other coronary risk factors. Elevated levels of lipoprotein-associated phospholipase A2 appear to be a strong risk factor for coronary heart disease, a finding that has implications for atherogenesis and the assessment of risk.
DISE: Directed Sphere Exclusion

The Sphere Exclusion algorithm is a well-known algorithm used to select diverse subsets from chemical-compound libraries or collections. It can be applied with any given distance measure between two structures. It is popular because of the intuitive geometrical interpretation of the method and its good performance on large data sets. This paper describes Directed Sphere Exclusion (DISE), a modification of the Sphere Exclusion algorithm, which retains all positive properties of the Sphere Exclusion algorithm but generates a more even distribution of the selected compounds in the chemical space. In addition, the computational requirement is significantly reduced, thus it can be applied to very large data sets.
Who Benefits When Enterprise Zones Are Zoned-Out ? The Case of the Ohio Enterprise Zone Program

In theory, enterprise zones target economically distressed areas. In practice, they do not. The dramatic expansion of the Ohio enterprise zone program to non-distressed areas allows us to examine three important theoretical and policy questions about enterprise zone usage and performance when enterprise zones are no longer targeted. First, if the state does not limit which municipalities can utilizes enterprise zones, which municipalities seek enterprise zone designation? Second, which enterprise zones generate the most new jobs and private investment? Third, where should Ohio designate its enterprise zones? We conclude with an analysis of the political dynamics and policy implications of expanding spatially targeted economic development policies to non-distressed areas. This study does not weigh in on whether the Ohio enterprise zone programs attracts investment and jobs. Instead, this research seeks to orient the discussion toward the question of who, or to be more accurate “where,” benefits.