Miracle-dz/UniFAR-FTUs huggingface dataset:
Nutritional status and health outcomes for older people with dementia living in institutions.

AIM This paper is a report of a study to determine changes over a 3-month period among older people with dementia living in long-term care settings, related to: (1) changes in body mass index, and (2) health outcomes and associated factors. BACKGROUND Nutritional deficiencies are common problems among older people, but frequently unrecognized, both in long-term care settings and in the community. METHOD A cross-sectional design with repeated measures of body weights and medical record reviews was adopted. The study was conducted in 2003 in two long-term care facilities for older people with dementia in Taiwan. Fifty-five residents participated in the study. RESULTS Eighteen percent of the residents were under-nourished (body mass index <18.5). There was a trend toward decreasing body mass index over the 3-month study period. Residents with low body mass index tended to need assistance at mealtimes. Nineteen residents, many receiving naso-gastric tube-feeding, experienced adverse health events during the study period. Dependency in eating was the major factor differentiating residents with normal or low body mass index values, and also in distinguishing those who experienced adverse health outcomes. CONCLUSION Assessment of eating ability, mode of feeding and measurement of body weight can be used by nurses in long-term care settings for early identification of the nutritional status of older people with dementia.
Combinación de clasificadores para el análisis de sentimientos

Resumen. El presente trabajo, propone una arquitectura fusionando los clasificadores: SVM, arboles de decision y Naive Bayes, mediante mayoŕia de votos, ventanas y cascada, para explorar el desempeno de la tarea de analisis de sentimientos. Se utilizo un corpus en espanol de 2625 opiniones, previamente preprocesado. Para representarlo, se emplearon bigramas, bolsa de palabras con pesado tf-idf, etiquetado POS y una representacion basada en la teoŕia de la valoracion. Los resultados obtenidos muestran una mejora en medida F del 18.13 %, con respecto a los resultados de los clasicadores base.
On the Mathematical Model of Vascular Endothelial Growth Connected with a Tumor Proliferation

In the paper the mathematical model of tumor growth is considered. New capillary network formation, which supply cancer cells with the nutrients, is taken into the account. A formula estimating a tumor growth in connection with the number of capillaries is obtained. Keywords—Differential Equations, Mathematical Models, Vascular Endothelial, Tumor
Quantitative Analysis of Computer Systems

Preface The Purpose of Quantitative Analysis The Nature of Computer Systems Events and Their Descriptions Resource Contention: Basic Parameters and Measures of Effectiveness Fundamental Relationships and Their Applications Systems with Service Discriminations Systems with Practical Limitations Networks of Queues Operational Analysis Database and I/0 Subsystem Performance Approximations and Time-Dependent System Behaviour Workload Modelling and Characterisation Performance Measurement and Monitoring Performance Tuning and Improvement System Simulation Bibliography.
AuSREM: Australian Seismological Reference Model

Although Australia has been the subject of a wide range of seismological studies, these have concentrated on specific features of the continent at crustal scales and on the broad-scale features in the mantle. The Australian Seismological Reference Model (AuSREM) is designed to bring together the existing information and provide a synthesis in the form of a 3-D model that can provide the basis for future refinement from more detailed studies. The model is grid based with a 0.5° sampling in latitude and longitude and is designed to be fully interpolable, so that properties can be extracted at any point. The crustal component makes use of prior compilations of sediment thicknesses, with cross-checks against recent reflection profiling, and provides P and S wavespeed distributions through the crust. The primary information for P wavespeed comes from refraction profiles, for S wavespeed from receiver function studies, and we are able to use the results of ambient noise tomography to link the point observations into national coverage. Density values are derived using results from gravity interpretations. AuSREM is able to build on a new map of depth to Moho, which has been created using all available information including Moho picks from over 10 000 km of full crustal profiling across the continent. In the upper mantle, the primary source of information comes from seismic surface wave tomography and a representative model has been developed to capture the features of a range of studies. Body-wave studies and regional tomography provide useful constraints on the relationship between P and S wavespeeds. The mantle model extends beyond the continent and so covers a larger area than for the crust. Below 350 km and in the surrounding area, AuSREM is linked to the S40RTS model. Potential applications of the AuSREM model come through the delineation of major structural features in the crust and mantle, and consequent improvements in, for example, earthquake location within the continent and at the nearby plate boundaries.
An Investigation of the Associations Between Measures of Mindfulness and Pain Catastrophizing

Objective:Mindfulness and pain catastrophizing are important constructs in pain research, and there are theoretical reasons for suspecting that measures of the 2 constructs should be related in predictable ways. The present study investigated the association of pain catastrophizing (Pain Catastrophizing Scale) with mindfulness (Five Facet Mindfulness Questionnaire). The Penn State Worry Questionnaire was included to control for confounding of worry; the influence of demographics was explored. Methods:The participants were 214 undergraduates, who were administered questionnaires via the Internet. Analyses assessed relationships after correcting for attenuation. Results:The mindfulness scales had intercorrelations with catastrophizing ranging from −0.23 to 0.13; the Non-Judging, Non-Reactivity, and Acting with Awareness mindfulness scales correlated significantly with catastrophizing. However, worry was better correlated (r=0.35) with catastrophizing, and the mindfulness scales were not significantly related to catastrophizing after controlling for worry. Mindfulness scales were significant predictors (P=0.018) of catastrophizing scores in a single-indicator latent variable analysis, and 1 mindfulness scale (Non-Reactivity) contributed uniquely (P=0.006) to prediction. None of the mindfulness scales significantly predicted catastrophizing scores when worry was controlled, but the path from worry to catastrophizing was significant (P=0.048). Sex differences in catastrophizing scores were explained by sex differences on the worry scale (P<0.001). Discussion:These findings suggest that it is important to assess more general cognitive-emotional constructs, such as worry, when making inferences about the influence of mindfulness or changes in mindfulness upon catastrophic thinking in response to pain.
ESTROGEN AND BRAIN : SYNTHESIS , FUNCTION AND DISEASES

1. ABSTRACT This review summaries recent evidence from clinical and basic science studies on estrogen central nervous system. For decades, estrogen was thought of only as a "sex hormone" and plays a fundamental role in regulating behavioral and physiological events. In recent years, accumulated evidence shows that estrogen also plays very important roles in the brain. Recent basic science studies show that estrogen treatment decreases the neuronal response to various forms of insult through the regulation of both estrogen synthesis and estrogen receptor expression in the brain. Some clinical evidence also suggests that estrogen deprivation might be implicated as a risk factor in various neurodegenerative diseases. Estrogen may play a neuroprotective role through estrogen dependent alterations in cell survival, enhancement of synaptic transmission and neurogenesis. Some of the mechanisms underlying these effects are independent of the classical nuclear estrogen receptors and involve direct modulation of neurotransmitter receptor function, or anti-oxidant activities of estrogen. It is controversial whether estrogen is indicated in the prevention or treatment of various brain disorders such as Alzheimer’s disease. The conflicting findings suggest that several variables, including age, estrogen dose and formulation, the length of treatment, may determine whether the potential benefits of estrogen treatment would outweigh the associated risks.
Pedestrian classification by using stacked sparse autoencoders

Automated Pedestrian classification has been the topic of interest over past many years. Various traditional and neural network based approaches have been adopted to recognize pedestrians. In this paper, we employ stacked sparse autoencoder as a deep learning building block for object feature extraction. Salient feature maps of the input images are generated with the help of SLIC superpixel-based graph manifold ranking. These salient maps are then served as input to the stacked sparse autoencoder in the next step. Softmax regression is selected as the classifier to identify the pedestrians. The learning and testing procedures are performed with the publically available datasets. The experiments results obtained are compared with a recent traditional pedestrian method. The better performance rates depict the robustness of the proposed approach.
DnaA‐ATP acts as a molecular switch to control levels of ribonucleotide reductase expression in Escherichia coli

Ribonucleotide reductase (RNR) is the bottleneck enzyme in the synthesis of dNTPs required for DNA replication. In order to avoid the mutagenic effects of imbalances in dNTPs the amount and activity of RNR enzyme in the cell is tightly regulated. RNR expression from the nrdAB operon is thus coupled to coincide with the initiation of DNA replication. However, the mechanism for the co‐ordination of gene transcription and DNA replication remains to be elucidated. The timing and synchrony of DNA replication initiation in Escherichia coli is controlled in part by the binding of the DnaA protein to the origin of replication. DnaA is also a transcription factor of the nrdAB operon and could thus be the link between these two processes. Here we show that RNA polymerase can form a stable transcription initiation complex at the nrdAB promoter by direct interaction with the far upstream sites required for the timing of expression as a function of DNA replication. In addition, we show that the binding of DnaA on the promoter can either activate or repress transcription as a function of its concentration and its nucleotide‐bound state. However, transcription regulation by DnaA does not significantly affect the timing of expression of RNR from the nrdAB operon.
Rapid Assessment of Sea Turtle and Marine Mammal Bycatch in the Union of the Comoros

The Union of the Comoros is host to internationally-significant populations of sea turtles, dugongs and cetaceans, all of which are potentially threatened by incidental catch in artisanal fishing gears. This work presented here was part of a larger initiative, known as Project GloBAL (Global Bycatch Assessment of Long-lived species), to evaluate artisanal fishing effort and bycatch of sea turtles and marine mammals in data-deficient areas. Questionnaire surveys were conducted with 409 out of the estimated 8,500 artisanal fishers in the Comoros, on the islands of Grande Comore (25/44 landing sites) and Moheli (5/13 landing sites). Sea turtles (mainly Chelonia mydas) were reportedly captured in large numbers, although it was not always clear if captures were accidental or deliberate. Lower rates of turtle capture were reported from Moheli, possibly as a result of awareness-raising activities associated with Moheli Marine Park. Gillnets presented the most serious bycatch-related threat to dugongs ( Dugong dugons ) and current mitigation efforts such as closed areas to limit gillnet use are essential for the continued presence of this species in the Comoros. Cetaceans were rarely captured and mortality was reportedly low; with spinner dolphin ( Stenella longirostris ) the most common of several species recorded as bycatch.
Blood Oxygen Tension Determination for the Recognition of Hypoxia in Newborn Babies and Older Infants1

Clinical signs of hypoxia, such as cyanosis, unconsciousness and respiratory embarrassment are not very reliable as indicators of the degree of oxygen lack. For example it is well known that cyanosis, usually considered the most important symptom, may be absent in severe oxygen lack in an anaemic patient. On the other hand, cyanosis may be present due to blood stasis in the skin without any hypoxia of more vital organs. Other clinical symptoms are not specific for hypoxia. Quantitative statements about the degree of hypoxia must be based on analysis of the blood gases. Analysis of arterial blood gases will demonstrate hypoxia only when there is deficient oxygen saturation in the lungs or a right-to-left-shunt. However, in the more common ischaemic hypoxia the arterial blood gases are normal. For this reason knowledge of the values of the venous blood gases are more important. -. -
Family of multicarrier bi-phase radar signals represented by ternary arrays

A K times L ternary array, comprised of the elements {0, 1, - 1}, with some unique features, represents a multicarrier radar signal with favorable autocorrelation and ambiguity functions. Constructing such an array using Galois fields is described. As in a Costas binary array, only one frequency is transmitted at any time slot, but in our array the same frequency is repeated in several time slots, yielding a signal with considerably larger pulse compression than a Costas signal that uses the same number of frequencies
MMG as a Communication Channel for the Disabled

This paper describes about an improved system to provide an effective communication tool for the people who are disabled. The Mechanomyogram (MMG) signal is used as a control signal for this system. Mechanomyogram signal is the superficial measurement of the low frequency vibrations that are emitted by muscles when they contract. The mentioned system acquires MMG signal from biceps brachii muscle and the temporalis muscle using microphone sensor. A communication window is developed using LabVIEW software which consists of various icons or LEDs that will specify various actions which the user needs to communicate. The users can select these icons by contracting their muscle which will generate MMG that will act as a control signal and select the icons. These icons when selected will execute a respective sound file that will be played aloud using speakers, thus communicating the needs of the user.
New observations on cell architecture and dynamics by video-enhanced contrast optical microscopy.

CONTENTS PERSPECTIVES AND OVERVIEW 266 IMAGE QUALITY . • • • • • 266 MICROSCOPE DESIGN 267 ENHANCEMENT •• • ••. •. •. •. •. •. ••. •• •. 268 Optical Enhancement 268 Photographic Enhancement 268 Electronic Enhancement 269 The Theory of Enhancement 269 Advantages of Video Enhancement 272 The Limitations of Enhancement 273 ENHANCEMENT AS A GENERAL METHOD IN MICROSCOPy 274 Distinctive Features of Different Enhanced Modes of Microscopy 276 A FRESH LOOK AT STRUCTURE AND FUNCTION IN LIVING CELLS 279 Cellular Structures Made Visible by Video-Enhanced Contrast 279
Mechanism-Based Inactivation of CYP3A by HIV Protease Inhibitors

Human immunodeficiency virus (HIV) protease inhibitors (PIs) are inhibitors of CYP3A enzymes, but the mechanism is poorly defined. In this study, time- and concentration-dependent decreases in activity as defined by maximum rate of inactivation (kinact) and inhibitor concentration that gives 50% maximal inactivation (KI) of CYP3A by amprenavir, indinavir, lopinavir, nelfinavir, ritonavir, and saquinavir were quantified using testosterone 6β-hydroxylation as a marker for CYP3A activity with recombinant CYP3A4(+b5), recombinant CYP3A5, and pooled human liver microsomes (HLMs). All the PIs, except indinavir, displayed inactivation with CYP3A4(+b5) and HLMs. Ritonavir was the most potent (KI = 0.10 and 0.17 μM) and demonstrated high kinact values (0.32 and 0.40 min-1) with both CYP3A4(+b5) and HLMs. Ritonavir was not significantly depleted by high-affinity binding with CYP3A4(+b5) and confirmed that estimation of reversible inhibition was confounded with irreversible inhibition. For CYP3A5, nelfinavir exhibited the highest kinact (0.47 min-1), but ritonavir was the most potent (KI = 0.12 μM). Saquinavir and indinavir did not show time- and concentration-dependent decreases in activity with CYP3A5. Spectrophototmetrically determined metabolic intermediate complex formation was observed for all of the PIs with CYP3A4(+b5), except for lopinavir and saquinavir. The addition of nucleophilic and free aldehyde trapping agents and free iron and reactive oxygen species scavengers did not prevent inactivation of CYP3A4(+b5) by ritonavir, amprenavir, or nelfinavir, but glutathione decreased the inactivation by saquinavir (17%) and catalase decreased the inactivation by lopinavir (39%). In conclusion, all the PIs exhibited mechanism-based inactivation, and predictions of the extent and time course of drug interactions with PIs could be underestimated if based solely on reversible inhibition.
Comparison Between Different Off-Season Resistance Training Programs in Division III American College Football Players

Hoffman, JR, Ratamess, NA, Klatt, M, Faigenbaum, AD, Ross, RE, Tranchina, NM, McCurley, RC, Kang, J, and Kraemer, WJ. Comparison between different off-season resistance training programs in Division III American college football players. J Strength Cond Res 23(1): 11-19, 2009-The purpose of this study was to examine the efficacy of periodization and to compare different periodization models in resistance trained American football players. Fifty-one experienced resistance trained American football players of an NCAA Division III football team (after 10 weeks of active rest) were randomly assigned to 1 of 3 groups that differed only in the manipulation of the intensity and volume of training during a 15-week off-season resistance training program. Group 1 participated in a nonperiodized (NP) training program, group 2 participated in a traditional periodized linear (PL) training program, and group 3 participated in a planned nonlinear periodized (PNL) training program. Strength and power testing occurred before training (PRE), after 7 weeks of training (MID), and at the end of the training program (POST). Significant increases in maximal (1-repetition maximum [1RM]) squat, 1RM bench press, and vertical jump were observed from PRE to MID for all groups; these increases were still significantly greater at POST; however, no MID to POST changes were seen. Significant PRE to POST improvements in the medicine ball throw (MBT) were seen for PL group only. The results do not provide a clear indication as to the most effective training program for strength and power enhancements in already trained football players. Interestingly, recovery of training-related performances was achieved after only 7 weeks of training, yet further gains were not observed. These data indicate that longer periods of training may be needed after a long-term active recovery period and that active recovery may need to be dramatically shortened to better optimize strength and power in previously trained football players.
Estimating Facets of Psychopathy From Normal Personality Traits

In three samples consisting of community and undergraduate men and women and incarcerated men, we examined the criterion validity of two distinct factors of psychopathy embodied in the Psychopathic Personality Inventory (PPI) as indexed by primary trait scales from the Multidimensional Personality Questionnaire (MPQ). Consistent with the PPI factors themselves, MPQ-estimated PPI-I related negatively with internalizing disorder symptoms and fearfulness and positively with thrill and adventure seeking, sociability, activity, and narcissism. MPQ-estimated PPI-II was associated negatively with socialization and positively with externalizing disorder symptoms, impulsivity, disinhibition and boredom susceptibility, and trait anxiety and negative emotionality. Additionally, PPI-I was selectively related to the interpersonal facet of Factor 1 of the Psychopathy Checklist—Revised (PCL-R), whereas PPI-II was related preferentially to Factor 2 of the PCL-R.
Helical fold prediction for the cyclin box

The smooth progression of the eukaryotic cell cycle relies on the periodic activation of members of a family of cell cycle kinases by regulatory proteins called cyclins. Outside of the cell cycle, cyclin homologs play important roles in regulating the assembly of transcription complexes; distant structural relatives of the conserved cyclin core or “box” can also function as general transcription factors (like TFIIB) or survive embedded in the chain of the tumor suppressor, retinoblastoma protein. The present work attempts the prediction of the canonical secondary, supersecondary, and tertiary fold of the minimal cyclin box domain using a combination of techniques that make use of the evolutionary information captured in a multiple alignment of homolog sequences. A tandem set of closely packed, helical modules are predicted to form the cyclin box domain.
Combinative stimulation inactivates sex pheromone production in the silkworm moth, Bombyx mori.

Mating results in a strong suppression of sex pheromone (bombykol) production in the female silkworm moth, Bombyx mori. The mechanical stimulation from the insertion of a penis, inflation of the bursa copulatrix (BC), or copulation with the sterile male whose penis was removed in order to prevent ejaculation (pr-male) induced only a partial decline in bombykol production. Artificial insemination stimulates oviposition of fertilized eggs as does normal mating. However, bombykol production did not decline in artificially inseminated females. When females were artificially inseminated before or after mating with pr-males, some females had a small amount of bombykol, similar to females mated with normal males, while other females had a large amount of bombykol similar to virgin females. The former usually laid fertilized eggs, while the latter laid only unfertilized eggs though semen filled their spermatophores and spermathecae. The mechanical stimulation caused by mating with a pr-male could be replaced by covering the abdominal tip with melted paraffin. Neither implantation of the BC obtained from mated females, nor injection of the spermatophore extract, into a female mated with a pr-male could inactivate bombykol production. Injection of hemolymph from a mated female into a virgin also failed to affect bombykol production These results indicate that a combination of both the tactile stimulation of the abdominal tip and the arrival of fertile spermatozoa in the vestibulum trigger a neural inactivation mechanism of bombykol production after mating.