Miracle-dz/UniFAR-FTUs huggingface dataset:
The etiology and diagnosis of occupational asthma.

In this review,the pathogenesis,clinical presentations,diagnosis of occupational asthma(OA)are discussed.The agents that cause OA are more than 300 kinds of high and low molecular-weight substances.The diagnosis of OA is generally established on the basis of a suggestive occupational history,symptoms,abnormal lung function and lab examination.Specific inhalation of bronchial challenge(SIC)comes closest to a gold standard test for some agents causing(sensitizer-induced)OA.
Avaliação da técnica de dopplerfluxometria e índice de resistividade das artérias renais em cadelas com piometra

33 Bitches with pyometra often develop transient renal changes. The study of methods to 34 investigate the renal injury in these bitches, as well as to understand the 35 pathophysiology of these changes, has been described in recent literature. Doppler 36 ultrasound provides important information about blood flow and vascular resistance of 37 the kidneys. This study evaluated the applicability of this resource in the renal 38 evaluation of 30 bitches with pyometra compared with 24 healthy bitches of the control 39 group, in diestrus and anestrus. With the exception of serum urea and creatinine, all 40 variables: leukocytes, platelets, hematocrit, protein/creatinine ratio, GGT/creatinine 41 ratio, urine specific gravity, renal perfusion and resistivity index (RI) of the main renal 42 arteries, cranial, middle and caudal interlobar arteries were different between the control 43 and experimental group. All the bitches with closed pyometra presented the median 44 values of the resistivity index above 0,7, the proposed value considered as borderline for 45 normality. Doppler study revealed changes in renal perfusion and RI of the main renal 46 and interlobar arteries in most affected bitches with pyometra. 47
Most Frequent Conditions in U.S. Hospitals, 2010

This Statistical Brief presents data from the Healthcare Cost and Utilization Project (HCUP) on the most common principal diagnoses in 2010 for all hospital stays in the United States, as well as for stays by age and primary payer. Changes in the overall number of stays and the rate of hospitalization in the population are presented for the most common conditions in 1997 and 2010. All differences between estimates noted in the text are statistically significant at the . 001 level or better.
Analysis of the Optimal Operation Frequency With Lowest Time-Delay Jitter for an Electrically Triggered Field-Distortion Spark Gap

This work was stimulated by the assumption that for a gas-filled spark gap closing switch operating at a high repetition frequency, there is an optimal frequency range in which the time-delay jitter reaches a minimum value. The experiments to test this assumption use an electrically triggered, field-distortion spark gap filled with the SF6/N2 gas mixture. The results show that indeed, the time-delay jitter decreases for a range of frequencies for which the filling gas can substantially restore the interelectrode insulation before increasing at a higher operation frequency. The experimental results demonstrate the correctness of the abovepresented assumption: the time-delay jitter of the field-distortion spark gap has its minimum when the unit operates in the repetition frequency range between 20 and 30 Hz. Since the recovery time depends on the gas species and the gap distance, the optimum operation frequency range should also vary depending on the spark–gap distance and the filling gas properties.
Analysis on the Course Design and Development of Freshman Seminar of Telecommunication Engineering

The Freshman Seminar is a student-centered, problem-oriented, seminar-based course and has unique value. To rationally choose the topic of discussion, design teaching content, and combine student research and teacher guidance from the actual needs of communication engineering students can improve the enthusiasm of students' independent learning and classroom participation, and effectively improve the quality of teaching. As a Double First-Class university, it can solve serious problems such as insufficient supporting teaching resources and students paying too much attention to utilitarian learning objectives by concentrating resources to build demonstration courses and strengthen refined management. Keywords—freshman seminar; demand orientation; teaching quality; teaching method
Symmetry at the Cellular Mesoscale

Symmetry plays a functional role in the structure and action of biomolecules and their associations and interactions in living cells. This symmetry is a natural consequence of the evolutionary mechanisms that lead to the development of life, and it ranges from perfect point-group symmetry in protein oligomers to more approximate symmetries in the higher-order mesoscale structure of cellular environments.
Managing waiting lists at an outpatient clinic by improving the production planning process

Waiting lists at hospitals are becoming an increased problem in Swedish healthcare. The requirements of efficiency at healthcare clinics increase further with political pressure of providing appointments within 90 days to all patients who seek specialized care. The gynecological outpatient clinic at Skaraborg’s hospital in Skovde is one of the Swedish clinics experiencing difficulties regarding the waiting list situation. It has been shown that an improved production planning and control (PPC) process can ease the waiting list situations in terms of increasing the controllability. The gynecological outpatient clinic at Skaraborg’s hospital in Skovde has therefore requested some improvement suggestions regarding the PPC process as means to control the waiting list situation in order to enable the clinic to sustain waiting lists within target levels. The purpose of this study is to provide such improvement suggestions. The study was conducted through gathering of data about the current PPC process at the gynecological outpatient clinic, by studying a different PPC process at another outpatient clinic at Skaraborg’s hospital, and by literature studies. The current PPC process was mapped and an analysis of the current situation was conducted. The analysis revealed six main problem areas in the current PPC process. The first three problem areas found were related to poor ability to adapt lower level planning with upper level planning, to lacking of a short term planning method and to planning based on the available staff rather than the requested staff. The other three problem areas were found within supporting functions of the PPC process. One was related to poor forecasting ability, one to poor considerations of care requests when planning and one to poor waiting list prediction ability. The problem areas then acted as a basis to generate improvement suggestions. An improved PPC process was suggested in which capacity planning was suggested to be based on capacity requirements, created by patient demand. Improved forecasting in combination with better information quality of care requests was also recommended. These changes would allow the clinic to foresee the capacity requirements and the development of the waiting list and thus provide the clinic with ability to react in time and, by doing so, control the waiting list levels. The improvement suggestions were critically evaluated and further studies were suggested to support the potential implementation of the improvement suggestions.
A Reversed-Phase HPLC Method for Determination of Osteopontin in Infant Formula

Osteopontin (OPN) is a multifunctional whey protein which has recently received much attention for possibly applications in fortifying infant milk formula (IMF) with its bioactivity. However, to date, there is no established high-performance liquid chromatography (HPLC) method to quantify this protein in milk or IMF. In this study, a rapid, simple, isocratic and reliable reversed-phase HPLC method was developed and validated to quantify the OPN in IMF. A C18 column (4.6 × 150 mm × 5 micron) was employed with 20% of 0.1% trifluoroacetic acid (TFA) and 80% of 60% acetonitrile in 0.1% TFA for 10 min detected at 214 nm. The flow rate was 0.3 mL/min with an injection volume of 10 µL. The column temperature was 40 °C, and the peak appeared after 4 min. The validation was based on the system suitability, linearity (r2 = 0.999), limit of detection (LOD) (0.14 mg/L), limit of quantitation (LOQ) (0.41 mg/L), precision (% relative standard deviation (RSD) < 0.2), recovery (% RSD < 3) and robustness. The results confirm that the method developed is suitable for OPN determination in IMF.
Factors Impacting the Students' Loyalty: An Empirical Investigation of Higher Education Sector In Pakistan

Student loyalty ensures management to take better strategies to improve the performance of any institute. The purpose of this research is to examine the factors impacting studentâ€™s loyalty through an empirical investigation of Higher Education Sector of Pakistan. The data for this research was collected through questionnaires from four major private universities of Karachi: SZABIST, IQRA University, Bahria University and Institute of Business Management (IOBM) with a sample size of 380. According to the nature of data, descriptive statistic and inferential statistics (regression & correlation) was used. In this research 51.6% respondents were male followed by females which are 47.9%. Results show that, female respondents are more inclined towards a university brand name and location as compare to males. On the side, males are more concerned about the universitiesâ€™ market value and faculty (teachers) as the major traits while choosing a particular university as compare to females. For universities facilities both the gender male and females have not shown much enthusiasm and interest. Moreover, program offered by the university, fee structure and extracurricular activities are not the primary focus for students (both male and females) as one of the university traits. Further the results demonstrate that, academic facilities and service attitude are highly correlated and have a great impact on studentâ€™s loyalty. Moreover, campus environment having a weaker correlation also impactâ€™s the studentâ€™s loyalty. Other factors like, HOD and program manager have a significantly weak correlation with student loyalty and at the same time does not produce any impact. This research responded the questions raised and welcomed a wide range of discussions for the university management to work closely for studentâ€™s welfare to enhance and maintain the studentâ€™s loyalty. The study is restricted within three HEC institutes of Karachi city only due to limited time frame and financial resources available.
The bearing capacity of footings on sand with a weak layer

Minor details of the ground, such as thin weak layers, shear bands and slickensided surfaces, can substantially affect the behaviour of soil–footing and other geotechnical systems, despite their seeming insignificance. In this paper, the influence of the presence of a thin horizontal weak layer on the ultimate bearing capacity of a strip footing on dense sand is investigated by single-gravity tests on small-scale physical models of the soil–footing system. The test results show that the weak layer strongly influences both the failure mechanism and the ultimate bearing capacity if its depth is lower than about four times the footing width. It is found that the presence of a thin weak layer can cause decreases of the ultimate bearing capacity of up to 80%. Numerical simulations, by finite-element analysis, of the behaviour of the reduced-scale models are able to capture the failure mechanism and the ultimate bearing capacity correctly, only if the mean equivalent constant value of the secant angle of sheari.
Proposition of a method based on mind maps to study changes in users' perceptions during an IS/IT adoption process

Although knowledge about IS/IT adoption is very broad, it is fragmented, and we still do not understand well how users move dynamically from one stage to another during the adoption process, that is, from when a user knows a new technology until, if the process is successful, she/he incorporates it into her/his routine. One of the causes of this theoretical limitation relates to the lack of methodologies that help researchers analyze longitudinally collected data and distinguish changes that occur over time as participants experience the implementation of the new system. In this article, we present a method based on mind maps that allows researchers to graphically synthesize the mental processes experienced by individuals as they adopt a new system. The method allows comparing and measuring changes among mental models of an individual in different stages of the adoption. Findings show that this method better reflects user perceptions than others based on surveys and technical processing of textual data. Using mind maps is a novel contribution to researching and understanding technology adoption in a holistic way and with methods that include time as a contextual variable in the adoption process.
A Qualitative Study to Explore the Experiences of Patients with Encapsulating Peritoneal Sclerosis

BackgroundAlthough relatively rare, encapsulating peritoneal sclerosis (EPS) is nonetheless a major concern within the renal community. Risk of developing EPS is associated with long-term peritoneal dialysis. Surgery now offers better outcomes. Research into EPS continues to focus on imaging and early detection methods, genetics, biomarkers and preventive strategies. No previous studies have examined patients? experiences of EPS, or their perception of the effect of EPS on health-related quality of life. AimsThe aim of the present study was to explore the experience of patients who have undergone surgery for EPS in one centre in the north of England.MethodsNine participants were recruited out of a total of 18 eligible. Most participants were interviewed twice conducted on two occasions over a 12-month period. This was October 2009 to October 2010.Analysis Interpretative data analysis was conducted, following the philosophical tradition of hermeneutics. Following the first interview a summary was sent to each participant before the second interview. Both interviews were analysed and are presented as themes.ResultsEPS presents the biggest challenge these patients have had to face since developing chronic kidney disease. Three major themes were identified each with subcategories: 1. Understanding EPS -self interpretation, ? not being heard? , gaps in information and knowledge, diagnosis shock and relief-confronting death 2. EPS an embodied experience- endurance, bodily awareness from others and within, struggles with eating 3. Adjustments and Transitions ? A journey of survival? - losses, support structures and their impact and locating self.ConclusionsThe findings of this study highlight a number of important issues relevant to clinical practice, including lack of information and understanding of EPS, particularly its early symptoms, the extent of the surgery and the support required. At the time patients transfer from peritoneal to haemodialysis, the provision of adequate information about the risks and potential early signs of EPS may improve not only their experiences but in addition may assist its early detection.
Development and Application of Biomarkers

Introduction to Biomarkers Application of Biomarkers in Diagnostics, Prognostics, Theranostics, and Personalized Medicine Introduction Nomenclature/Definitions Biomarkers and Diagnostics Biomarkers and Screening Biomarkers and Prognosis Biomarkers and Theranostics and Personalized Medicine Biomarkers and Specific Pathologies Rheumatoid Arthritis Inflammation Biomarkers in Different Pathologies Biomarkers in Ophthalmology Biomarkers in Neurology Cardiac Biomarkers Biomarkers in Renal Disease Biomarkers for Bone Biomarkers for Exposure to Environmental Toxins Biomarkers and the Development of Biopharmaceuticals Development of Biomarkers for Oncology Intermediate Biomarkers and the Precancerous Condition Cancer and Inflammation Head and Neck Cancer Ovarian Cancer Pancreatic Cancer Prostate Cancer Breast Cancer The Use of Proteomics to Discover Biomarkers Blood Urine Saliva Miscellaneous Biological Fluids/Excretory Products as Sources of Biomarkers Biomarkers in Tissue Samples Modified Proteins, Oligosaccharides, and Oligonucleotidesas Biomarkers Complex Biomarkers: Cells, Cell Membrane Proteins, and Cell Fragments as Biomarkers Use of Microarray Technology in Biomarker Discovery and Development Development of Assays for Biomarkers Appendix A: Model Standard Operating Procedure for an Assay references provided at the end of every chapter
Evidence based management of hepatitis

Introduction: Predniso(lo)ne with or without azathioprine is considered the mainstay in the treatment of autoimmune hepatitis (AIH), but many therapeutic options are available. The primary objective of this review was to explore the published literature on the optimal induction and subsequent maintenance therapy for AIH. Methods: We performed a systematic search on electronic databases MEDLINE (195007.2009), Web of Science and Cochrane and the website www.clinicaltrials. gov. Randomized controlled trials (RCTs) on apparent beneficial treatment regimens as induction or maintenance treatment in AIH were included. Pediatric studies were excluded. We calculated relative risks (RR) for comparison of treatment options on the primary outcome measure, which was defined as clinical, biochemical and histological remission. Results: Eleven RCTs were included, of which 7 studies evaluated the induction therapy in AIH patients: 3 treatment-naive (n = 253), 2 relapse (n = 53), 2 combination of naive and relapse (n = 110). The remaining 4 studies (n = 162) assessed maintenance therapy. All but one maintenance study (thymostimulin versus no therapy) studied predniso(lo)ne (PRED), azathioprine (AZA) or combination PRED+AZA. We found no differences in primary outcome between induction therapy with PRED and PRED+AZA in treatment naive patients (RR=0.98; 95%CI 0.65-1.47). AZA monotherapy as induction was considered as not viable because of a high mortality rate (30%). This was similar in AIH patients who relapsed: RR for PRED vs PRED+AZA for inducing remission was not different: 0.71 (95%CI 0.37-1.39). PRED+AZA maintained remission more often than PRED (RR=1.40; 95%CI 1.13-1.73). Also AZA maintained a higher remission rate than PRED (RR=1.35; 95%CI 1.07-1.70). Maintenance of remission was not different between PRED+AZA and AZA (RR=1.06; 95%CI 0.94-1.20). Conclusions: Based on available RCTs PRED monotherapy and PRED+AZA combination therapy are both viable induction therapies for AIH treatment naives and relapsers, while for maintenance therapy PRED+AZA and AZA therapy are superior to PRED monotherapy. Chapter 2
Editor’s Introduction

The psychosocial aspects of disasters have long been established as an area of research, service delivery, education and training, and policy making and planning. Increasing attention has been given to the psychological impact on both victims and rescue workers in the emergency phase, in preparedness, in search and rescue operations, and in terms of immediate aftereffects. Yet, despite the fact that forty-five years have elapsed since Lindemann [1] elucidated many of the principles of crisis intervention, following the tragedy of the Boston Coconut Grove fire, relatively little has been done to ameliorate the long-term psychosocial consequences of disasters. Even more important is that there is still precious little in the way of planning and preparation for disasters. Disaster response remains largely a media-inspired and -"mediated" event. Prompted by media reports, people often rush to save lives following an airplane crash or during a famine. They may act generously and heroically; but without training or guidance, their response is not always helpful. For example, when a plane crashed recently in New York, people rushed to help thereby clogging the roads and preventing trained personnel from reaching the scene quickly.
Stoller's Atlas of Orthopaedics and Sports Medicine

MRI Normal Anatomy: Lower Extremity The Hip The Knee The Ankle and Foot MRI Normal Anatomy: Upper Extremity The Shoulder The Elbow The Wrist and Hand The Hip The Knee The Ankle and Foot Entrapment Neuropathies of the Lower Extremity Articular Cartilage The Shoulder The Elbow The Wrist and Hand The Finger Entrapment Neuropathies of the Upper Extremity Marrow Imaging Bone and Soft-Tissue Tumors
A Concise Psychometric Tool to Measure Personal Characteristics for Surviving Natural Disasters: Development of a 16-Item Power to Live Questionnaire

The ability of individuals to manage and rebuild their lives after a disaster depends on environmental factors, as well as their own psychological characteristics. A psychometric questionnaire to measure personality traits relevant to disaster survival was proposed based on a large-scale investigation of survivors of the 2011 Great East Japan Earthquake (Sugiura et al. 2015). This tool, the Power to Live with Disasters questionnaire, measures eight personality characteristics that are beneficial for coping with disasters. However, this instrument has not been optimised for practical use; it is long and lacks benchmark scores for the general population. Thus, we developed a concise, 16-item version of the Power to Live with Disasters questionnaire through reanalysis of the 2011 Great East Japan Earthquake survivor data and an additional Web-based survey to obtain normative data from 1200 respondents drawn from the general population of Japan. The scores obtained from the short-form version of the questionnaire successfully replicated the results of the long-form version; eight distinct personality characteristics correlated well with several items associated with “successful survival” of the 2011 earthquake and tsunami. The normative data of the full- and short-version questionnaires were also highly correlated. We propose use of the shortened questionnaire to determine the personality traits critical for survival in the face of unexpected, life-threatening situations caused by natural disasters. Our questionnaire could be useful in schools and other public settings to enhance disaster-mitigation efforts and resilience to disasters in the general population.
A novel LMI-based robust adaptive model predictive control for DFIG-based wind energy conversion system

In wind turbine systems, the optimal, effective and robust operation of the doubly fed induction generator (DFIG) is especially important. This paper presents a new robust adaptive control method for DFIG generator in a variety of operating conditions. First, an adaptive observer is used for parametric uncertainty, external disturbances and nonlinear terms effects estimation with reasonable assumptions. Then through obtained estimation and using the LMI method, the robust adaptive model predictive control controller is designed for DFIG dynamics and its robust stability is shown against the mentioned effects. Simulation results indicate that the proposed controller is capable to meet the required specifications for active and reactive power control of DFIG in different operating conditions.