Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of ticagrelor with or without aspirin on vein graft outcome 1 year after on-pump and off-pump coronary artery bypass grafting

Background In the present post hoc analysis of the DACAB trial, we evaluated the effects of ticagrelor with or without aspirin on 1-year vein graft outcomes after coronary artery bypass grafting (CABG) with and without cardiopulmonary bypass (CPB) (on-pump and off-pump). Methods The DACAB trial was a multicenter, randomized, open-label, parallel control study enrolling 500 patients with 1,460 vein grafts undergoing CABG. For current post-hoc study, all patients in the DACAB study were included in the analysis to compare the effects of different antiplatelet regimens under on/off pump. Patients were randomly assigned to 1 of 3 antiplatelet treatment regimens (ticagrelor plus aspirin, T + A; ticagrelor alone, T; or aspirin alone, A) within 24 hours after CABG, and were stratified into on-pump and off-pump subgroups. The primary outcome was 1-year vein graft patency rate. Results Totally 121 patients underwent on-pump CABG (39 with 121 vein grafts in T + A, 36 with 101 vein grafts in T, and 46 with 137 vein grafts in A) and 379 patients underwent off-pump CABG (129 with 336 vein grafts in T + A, 130 with 387 vein grafts in T, and 120 with 348 vein grafts in A). Compared with A, T + A showed a higher 1-year vein graft patency rate in both on-pump (adjusted OR for non-patency =0.62, 95% CI: 0.16–2.45) and off-pump (adjusted OR for non-patency =0.35, 95% CI: 0.20–0.62) subgroups, P interaction =0.647; whereas T did not in either on-pump (adjusted OR for non-patency = 0.92, 95% CI: 0.31–2.76) or off-pump (adjusted OR for non-patency =0.58, 95% CI: 0.34–1.00) subgroups, P interaction =0.430. Conclusions In the DACAB trial, for patients underwent either on-pump or off-pump CABG, ticagrelor plus aspirin showed consistent benefit for achieving 1-year vein graft patency, with particular benefit being seen in the off-pump.
CHANGES IN CORNEAL BIOMECHANICS AFTER REFRACTIVE SURGERY USING CORVIS ST - A QUASI EXPERIMENTAL STUDY

Objective: To assess the corneal biomechanical changes after refractive surgery using Corvis ST (Oculus Wetzlar, Germany) a dynamic scheimpflug analyzer. Study Design: Quasi experimental study. Place and Duration of Study: The study was conducted at Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi, from Feb 2019 to Jul 2019. Methodology: Following strict inclusion criteria 32 patients were recruited in the study. Total of 64 eyes of patients underwent refractive surgery. Laser in situ keratomileusis (LASIK) was performed on 44 eyes and Photorefractive keratectomy (PRK) was performed on 20 eyes. All measurements for assessment of corneal biomechanics generated by Corvis ST were taken before surgery, 1 week and one month after the procedure with scheimpflug based device (Corvis ST, oculus). Results: In LASIK surgery after a week there was a change in pachymetry, A1 length, radius and IOP and at one-month pachymetry, deformation amplitude, A1 time, A1 length, A2 length, radius, Intraocular pressure (IOP) and peak distance came out statistically significant with a p-value of <0.05. In PRK group Pachymetry, A1 length and radius were statistically significant (p-value <0.05) after a month with no difference in parameters after one week. Conclusion: Our study concluded that there were modifications in biomechanical parameters after LASIK and PRK, indicating changes in cornea after refractive procedures with PRK being less aggressive than Lasik.
Is there a difference between synchronous multiple primary cancer and metastasis cancer?

The purpose of this study was to evaluate synchronous multiple primary neoplasms of gynecologic origin in terms of clinical features, diagnosis, treatment, and relapse. Seven patients treated from 2012 to 2017 were studied; five of whom had synchronous multiple primary neoplasms associated with endometrial cancer. Two patients recurred and additional chemotherapywas performed. Synchronousmultiple primary neoplasms have a better prognosis than single metastatic tumors, but they should be followed up carefully, as they tend to recur in the latter half of treatment. The authors herein report these seven cases along with a brief review of the literature.
Abnormal Topological Organization of Sulcal Depth-Based Structural Covariance Networks in Parkinson's Disease

Recent research on Parkinson's disease (PD) has demonstrated the topological abnormalities of structural covariance networks (SCNs) using various morphometric features from structural magnetic resonance images (sMRI). However, the sulcal depth (SD)-based SCNs have not been investigated. In this study, we used SD to investigate the topological alterations of SCNs in 60 PD patients and 56 age- and gender-matched healthy controls (HC). SCNs were constructed by thresholding SD correlation matrices of 68 regions and analyzed using graph theoretical approaches. Compared with HC, PD patients showed increased normalized clustering coefficient and normalized path length, as well as a reorganization of degree-based and betweenness-based hubs (i.e., less frontal hubs). Moreover, the degree distribution analysis showed more high-degree nodes in PD patients. In addition, we also found the increased assortativity and reduced robustness under a random attack in PD patients compared to HC. Taken together, these findings indicated an abnormal topological organization of SD-based SCNs in PD patients, which may contribute in understanding the pathophysiology of PD at the network level.
Interannual variability of Tropical Atlantic and its influence on extreme precipitation events: Focus on the Amazon Basin

This study provides a detailed analysis, in the interannual time-scale, of the influence of the tropical Pacific and the Atlantic Ocean in the precipitation regime over South America, with a focus on the Amazon Basin. For this purpose, first, monthly sea surface temperature data is used to determine the principal modes of variability in three Atlantic regions: Tropical North Atlantic (TNA), Tropical South Atlantic (TSA), and Subtropical South Atlantic (STSA). These patterns are obtained from Empirical Orthogonal Function (EOF), where the first mode (PC1) of each region explains the interannual variability in high percentage. The PC1 time series also shows SST peaks related to extreme precipitation events in the Amazon Basin. In addition, the Pacific and Atlantic interaction was analyzed by moving correlations and cross-wavelets for the 1880-2017 period, using Pacific indices (E and C index) and the PC1 of each Atlantic region. We found that the Atlantic regions have been coupling and decoupling in specific periods. Likewise, the Pacific and the Atlantic oceans have been shown in-phase or in opposite phase in different periods of time and frequencies. Precipitation from satellite and combined observed-satellite for the 1940-2010 period were used to identify regions influenced by the Pacific and Atlantic SST. The results suggest that different El Niño Southern Oscillation (ENSO) flavors mainly impact precipitation during the onset (October-November) and peak (December-February) of the South America Monsoon System (SAMS). We have also shown that anomalous conditions over the Tropical North and South Atlantic Ocean impact precipitation regimes during the demise (March-April) and the absence of the SAMS (May-September), while the Subtropical South Atlantic impacts in precipitation during the peak and the absence of the SAMS. Additionally, moisture flux, its divergence, and vertical structure over South America and the adjoining oceans were obtained for different conditions of tropical oceans, through the oceanic indices. Results show that anomalous conditions of sea surface temperature in these oceanic regions modify the source and sink regions for atmospheric moisture in all seasons. A reduction in the moisture inflow, mainly in warm tropical Atlantic conditions, could lead to extremely dry periods in central-southern Amazon and the northern La Plata Basin. This effect, indeed, could be even more extreme in tropical South America when it is preceded by the El Niño event. However, contrasted impacts are observed during El Niño years, with rainfall deficit in tropical South America, east of the Andes, and rainfall excess over southeastern South America and northwest of the Andes (northern Peru, coastal Ecuador, and Colombia). These findings provide an analysis that will help to improve adaptation and risk management policies related to impacts of climate variability and change.
The Influence of Melt-Mixing Conditions and State of Dispersion on Crystallisation, Rheology and Mechanical Properties of PCL/Sepiolite Nanocomposites

Abstract It is generally accepted that the benefit of anisotropic nanofiller addition is strongly dependent on the state of the dispersion of these fillers in a polymer matrix. In this paper the influence of melt-compounding conditions on the dispersion of a needle-like clay, i. e. sepiolite, in poly(∊-caprolactone) (PCL) is investigated. The crystallisation behavior as well as the rheological and mechanical properties of PCL/sepiolite nanocomposites with filler contents up to 5 wt. % are studied. By changing the screw speed during melt-mixing in a micro-compounder, the state of dispersion was varied, with the higher speed leading to better dispersion and breakdown of the sepiolite agglomerates or bundles. Rheometry showed that better dispersed nanocomposites displayed an increase in viscosity due to network formation at slightly higher filler loadings. Likewise, better dispersed composites showed a modest increase in crystallisation temperature at low filler content, accompanied by a decrease in both nucleation efficiency and degree of crystallisation at higher loadings. Better dispersed nanocomposite systems also showed superior mechanical properties, particularly at higher filler loadings. However, overall the reinforcing efficiency of sepiolite in all nanocomposites was relatively low. This was mainly a consequence of the relatively low filler aspect ratio and the simultaneous breakup of sepiolite needles together with a breakdown of bundles during compounding.
Schwertmannite on Mars? Spectroscopic analyses of schwertmannite, its relationship to other ferric minerals, and its possible presence in the surface material on Mars

Schwertmannite, a hydroxylated ferric sulfate mineral, is presented as a possible component of the surface material on Mars. Schwertmannite could have formed on Mars through chemical weathering processes as acidic groundwater came in contact with the atmosphere. Visible and infrared spectra of schwertmannite are presented here and analyzed in context of spectra of other ferric minerals and Mars soil analogs. Infrared transmittance spectra and Moessbauer spectra of schwertmannite are studied as well to facilitate interpretation of the reflectance spectra. The visible region spectra of schwertmannite are similar to those of jarosite andakaganeite in that they are dominated by a broad Fe3+ transition near0.91 muem and a local reflectance maximum near 0.73 muem. Spectra of schwertmannite are relatively bright in the near infrared and exhibit broad bound and absorbed water features near 1.45, 1.95 and 3 muem. The mid-infrared region spectra are significantly darker and include a water feature near 6.1 muem and several weak sulfate and OH features at longer wavelengths. The formation conditions and spectral features of schwertmannite are consistent with those of the ferric sulfate phase present in chemically-treated ferric sulfate- bearing montmorillonites, which have been examined as Mars soil analogs. Methods suitable for detecting the possible presence of schwertmannite in the Martian surface soils are discussed, as well as implications for the surface geochemistry of Mars should schwertmannite occur there.
Estudo de soluções sólidas da mulita : fabricação e propriedades.

In the present work a study is made about manufacture of mullite ceramic compacts by synthesis from mechanical mixture of silica (SiO2) and alumina (Al2O3) powders with different compositions by sintering. The silica powder used as starting material for the mullite production was obtained from the calcination of chemically treated rice husk, at temperatures of 550oC during 4h and 700oC, for comparison. The powders were initially mixed mechanically, uniaxially pressed, and sintered at 1650oC in a muffle type furnace, for approximately 4h, in air atmosphere. Some samples were re-sintered in order to verify the time influence in the mullitization process during the sintering. The mixture process was optimized using the orbital disc mill coated with alumina and calcination of the mixed α- alumina and silica powder at temperature of 1100 oC during 4h. The microstructure of the sintered ceramic compacts was characterized by Scanning Electron Microscopy (SEM). The phase characterization of the sintered compacts was carried out by X-ray diffraction. The relation between the alumina content in the sintered mullite and the lattice parameter “a” was calculated by the relation m = 144.5a –1029.5, where “a” is the lattice parameter. The effect of the composition to the electric conductivity of the mullite was analyzed by measures of electric resistivity at room temperature. This study shows that working with the experimental conditions described is possible to manufacture mullite with low density, microstructure presenting equiaxial grains with sizes varying in the range of 2 to 3 μm, and the composition varying of 70 to 74 wt. % of alumina that corresponds the mullite 3:2 and 1.64:1, respectively. These results also show that sintering time is an essential factor to be considered in order to reach a high mullitization content when it is intended to get mullite by sintering of α-alumina and silica powders at temperature of 1650oC.
Personality, occupational sorting and routine work

PurposeA prominent labour market feature in recent decades has been the increase in abstract and service jobs, while the demand for routine work has declined. This article examines whether the components of Type A behaviour predict workers' selection into non-routine abstract, non-routine service and routine jobs.Design/methodology/approachBuilding on the work by Barrick et al. (2013), this article first presents how the theory of purposeful work behaviour can be used to explain how individuals with different levels of Type A components sort into abstract, service and routine jobs. Then, using longitudinal data, it examines whether the components of Type A behaviour predict occupational sorting. Estimations were performed based on the linear regression method.FindingsThe results show that the Type A dimension “leadership” was associated with a higher level of abstract and service job tasks in occupation. High eagerness-energy and responsibility were also positively linked with occupation's level of abstract tasks. These results suggest that workers sort into jobs that allow them to pursue higher-order implicit goals.Originality/valueJob market polarisation towards low-routine jobs has had a pervasive influence on the labour market during the past few decades. Based on high-quality data that combine prime working-age register information on occupational attainment with information about personality characteristics, the findings contribute to our knowledge of how personality characteristics contribute to occupational sorting in terms of this important job aspect.
Business and Society Research Drawing on Institutionalism: Integrating Normative and Descriptive Research on Values

Business and society (B&S) scholarship that uses the theoretical perspective of institutionalism combines different research approaches to values. Within the B&S literature drawing on institutionalism, we identified and categorized the research on values according to a spectrum of normative and/or descriptive approaches (including both and neither approaches). Primarily, we focused on how the normative and descriptive approaches interrelate and integrate. We argue that drawing on John Dewey’s pragmatism and Philip Selznick’s institutionalism can help further an integrative approach, which holds great potential for advancing theorization in the B&S field while increasing its practical relevance.
Estudio histórico y recreación virtual 3D del Panteón de los Ciudadanos Meritorios -Cementerio de la Recoleta- de Carlo Zucchi

is work presents the 3D digital visualization of a working hypothesis within the framework of the research advances of the master's thesis of one of the authors. It focuses on the combination of historical research in architecture and art and the use of 3D digitization techniques (3D modeling and 3D recording). e study of a set of funerary monuments of the Recoleta Cemetery (Buenos Aires, Argentina) called e Pantheon of Meritorious Citizens, erected between 1832 and 1834, existing today and the 3D reconstruction of the project of the Pantheon to the Illustrious Men of the Fatherland. Both elaborated by or with the intervention of Carlo Zucchi, Architect-Engineer of the Province of Buenos Aires at that time. e monuments studied are those dedicated to: Cornelius Saavedra (1831); Gregorio Funes (1831); Gregorio Perdriel (1832); Marcos Balcarse (1832); Antonio Sáenz (1833) and Juan Izquierdo (died 1834).
Biosafety of genetically modified wheat (Triticum aestivum) Hi-line 111

Genetically modified (GM) crops were approved for edible use in several countries but their biosafety for organisms remains to be crucial. The objectives of this work were to compare GM wheat (Triticum aestivum) Hi-line 111 (GMW) with native non-GMW wheat (NGMW) to ﬁnd the diﬀerences, if any, in their biosafety. Three groups of albino rats (Rattus norvegicus) were used to study the biosafety of GMW for 30 days. Group 1 was fed on a basal diet (control), and group 2 on a control diet with 30% replacement of starch with NGMW, while group 3 was fed on the control diet with 30% replacement of starch with GMW. There were no significant signs of adverse impacts noted in the clinical appearance of animals fed on GMW in terms of initial body weight, absolute or relative organ weights and serum profile in comparison with the control group. However, slight histopathological changes were observed in the organs of animals fed on GMW. Though our results demonstrate GMW biosafety regarding its biochemical parameters, however, detailed description of submucosal edema and further studies on allergenic potential with long feeding periods should be performed to conclude its impacts on health.
QUEBRA DE PRODUTIVIDADE E PERÍODO ÓTIMO DE CULTIVO PARA A CULTURA DO MILHO NO SEMIÁRIDO CEARENSE

The estimation of productivity and the definition of the best growing periods are important factors in obtaining satisfactory technical and economic indicators for the management of rainfed corn in the semiarid region. Therefore, the objective was to estimate the productivity of rainfed corn in different rainfall scenarios and indicate the appropriate period for its cultivation in the municipality of Crateús-Ce, analyzing the
Energy Efficiency Optimization Algorithm of CR-NOMA System Based on SWIPT

This paper proposes a system EE (energy efficiency) optimization algorithm based on OPS (On-off Power Splitting) strategy for SWIPT (Simultaneous Wireless Information and Power Transfer) two-way relay assisted CR-NOMA (Cognitive Radio Non-Orthogonal Multiple Access) network. The system capacity expression of the secondary users with the OPS strategy is derived. Under the constraints of harvested energy and quality of service (QoS) of the users, the optimization problem with the goal of maximizing energy efficiency is constructed. In this paper, the NP-Hard problem is transformed into three subproblems about relay power, NOMA coefficient, and segmentation coefficient, which are solved by golden section algorithm, monotonicity decision function, and genetic algorithm. The simulation results show that compared with the PS (Power Splitting) and TS (Time Switching) strategies, the OPS strategy can significantly improve the transmission energy efficiency of the system.
Circularly Polarized Patch Antenna With Filtering Performance Using Polarization Isolation and Dispersive Delay Line

A circularly polarized (CP) filtering patch antenna implemented via dispersive delay line (DDL) is proposed in this letter by adopting a new strategy of polarization isolation. Different from a linearly polarized antenna, the effective radiation gain of a CP antenna, i.e., CP gain, is not only determined by the magnitude of electric field but also its phase. For a CP antenna, left-hand circular polarization (LHCP) has perfect isolation with the right-hand one, which has nothing with the orientation between transmitters and receivers. As such, the aforementioned concept is especially used in the proposed design of CP filtering antenna and achieved by DDL, which works as a key technique in the proposed antenna. By controlling the parameters of DDL, the in-band and out-of-band phases of two orthogonal electric components are effectively changed, thus affecting the axial ratio, and finally leading to opposite CP radiations of in-band and out-of-band, which means that the filtering performance has been realized. For demonstration, an antenna prototype operating in the 2.4 GHz ISM band is fabricated and measured. The simulated and measured results match well with each other. More importantly, the feasibility of the proposed CP filtering strategy is verified by the good filtering performance of CP radiation gain.
Classification of Heart Sounds Using Convolutional Neural Network

Heart sounds play an important role in the diagnosis of cardiac conditions. Due to the low signal-to-noise ratio (SNR), it is problematic and time-consuming for experts to discriminate different kinds of heart sounds. Thus, objective classification of heart sounds is essential. In this study, we combined a conventional feature engineering method with deep learning algorithms to automatically classify normal and abnormal heart sounds. First, 497 features were extracted from eight domains. Then, we fed these features into the designed convolutional neural network (CNN), in which the fully connected layers that are usually used before the classification layer were replaced with a global average pooling layer to obtain global information about the feature maps and avoid overfitting. Considering the class imbalance, the class weights were set in the loss function during the training process to improve the classification algorithm’s performance. Stratified five-fold cross-validation was used to evaluate the performance of the proposed method. The mean accuracy, sensitivity, specificity and Matthews correlation coefficient observed on the PhysioNet/CinC Challenge 2016 dataset were 86.8%, 87%, 86.6% and 72.1% respectively. The proposed algorithm’s performance achieves an appropriate trade-off between sensitivity and specificity.