Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effect of Processing Parameters on the Properties of Fish Gelatin Hydrolysate Nanoparticle

Fish gelatin hydrolysate is a well- known fish by-product that is high in protein content. It is produced from by-product waste from the fish processing industry, which includes fish skin, head, and bones. Gelatin hydrolysates have recently received much attention due to its high protein content and bioactivity, which includes antioxidant, antimicrobial and antihypertensive activities. The transformation of gelatin hydrolysate into nanoparticles is believed to increase its economic value. Furthermore, reduction into nano-size increases the absorption characteristic of this material. Here, fish gelatin hydrolysate nanoparticles are prepared for the first time using desolvation method. The effects of concentration of gelatin hydrolysate, pH of solution, and acetone concentration on nanoparticle size are determined. The prepared gelatin hydrolysate nanoparticles were found to have spherical shape with sizes varying from 300-400 nm with a mean size of 408 ± 11.4 nm, zeta potential of -16.4 ± 1.2 mV and PDI 0.203 ± 0.07. This study showed that concentration of gelatin hydrolysate, pH and concentration of solvent have significant effects on nanoparticle size. The gelatin hydrolysate nanoparticles can be applied in the pharmaceutical industry for the encapsulation of drugs to facilitate delivery to target sites.
Impact of free curcumin and curcumin nanocapsules on viability and oxidative status of neural cell lines

Abstract Curcumin is an active polyphenol substance found in the highest concentrations in the roots of Curcuma longa. Its health benefits have led to recent increases in the consumption of curcumin. It has anti-inflammatory and antioxidant activities and is a potent neuroprotective against diseases of the brain. Nevertheless, its low bioavailability and its relative difficulty crossing the blood-brain barrier limit curcumin’s use for these purposes. Curcumin-loaded nanoparticles may be an effective treatment for several diseases although there is a paucity of studies reporting its safety in the central nervous system (CNS). Therefore, this study aimed to identify non-neurotoxic concentrations of free curcumin and two nanoformulations of curcumin. Cell lines BV-2 and SH-SY5Y, both originating from the CNS, were evaluated after 24, 48, and 72 h of treatment with free curcumin and nanocapsules We measured viability, proliferation, and dsDNA levels. We measured levels of reactive oxygen species and nitric oxide as proxies for oxidative stress in culture supernatants. We found that free curcumin was toxic at 10 and 20 µM, principally at 72 h. Nanoformulations were more neurotoxic than the free form. Safe concentrations of free curcumin are between 1–5 µM, and these concentrations were lower for nanoformulations. We determined the ideal concentrations of free curcumin and nanocapsules serving as a basis for studies of injuries that affect the CNS.
Role of Anionic Surfactants in the Synthesis of Smart Microgels Based on Different Acrylamides

We investigated the influence of two anionic surfactants, namely, sodium dodecyl sulfate and sodium decyl sulfate, on acrylamide-based microgels consisting of N-n-propylacrylamide. In this context, the main focus was on the influence of surfactant addition on the size of the microgels. The surfactant was added to the reaction mixture before or during the polymerization at different points in time. Microgels were characterized via photon correlation spectroscopy and atomic force microscopy. All results were compared to those for other more common acrylamide-based microgels consisting of N-isopropylacrylamide and N-isopropylmethacrylamide. A significant difference between the three microgels and a strong dependence on the surface activity of the surfactant was found.
Textile-Based Flexible Pressure Sensors: A Review

Abstract This paper provides a review of recent developments in the rapidly changing and advancing field of textile-based flexible pressure sensors. It summarizes the basic principles and approaches employed when building textile-based pressure sensors as well as the most commonly used materials and techniques. The textile pressure sensor is a promising candidate for the next-generation sensing platform since it can be easily incorporated into modern garments in a breathable and conformable way. This article briefly introduces the characteristics of piezoelectric, capacitance, piezoresistive and triboelectric flexible pressure sensors, focuses on the working principles of these four types of flexible pressure sensors and reviews their recent progress and applications in electronic skin, health care and rehabilitation, human motion capture, physiological activity monitoring and human-machine interaction. Moreover, the remaining challenges in the development process and prospects of textile-based flexible sensors are discussed.
Endurance training intensity has greater effects than volume on heart rate variability and arterial stiffness adaptations in sedentary adult men: A Randomized Controlled Trial.

Background: The current study investigated the chronic effects of high-volume moderate-intensity training and low-volume high-intensity training on heart rate variability (HRV) and arterial stiffness in sedentary adult men. Materials and methods: Forty-five males (age: 42± 5.7 yrs.) were randomly assigned into control group (n=15), high-volume moderate-intensity training (HVMIT) (n=15), and low-volume high-intensity training (LVHIT) (n=15). The HVMIT group ran three times per week, on the treadmill at 50% to 60% of VO2max for 45 to 60 minutes, while the LVHIT trained at 70% to 85% of VO2max for 25 to 40 minutes. Both training programs were equated by caloric expenditure. HRV, Pulse Wave Velocity (PWV), hemodynamic variables, and body composition were measured before and after 12 weeks.Results: Both protocols (HVMIT and LVHIT) significantly increased the Standard deviation of NN intervals (SDNN) and High-frequency (HF) bands after 12 weeks (p ˂ 0.05). The LF/HF ratio decreased significantly in both training groups (p ˂ 0.05). However, these changes were significantly greater in the LVHIT protocol (p ˂ 0.05). Furthermore, the Root mean square of successive RR interval differences (RMSSD) significantly increased only in the LVHIT protocol (P ˂ 0.05). Moreover, a significant decrease in low-frequency (LF) and PWV was only observed following the LVHIT protocol (P ˂ 0.05). Conclusion: This study indicates that the LVHIT protocol is more effective and efficient for improving HRV variables and PWV than the HVMIT protocol.
X-Band Feedback Type Miniaturized Oscillator Design With Low Phase Noise Based on Eighth Mode SIW Bandpass Filter

A standard substrate integrated waveguide (SIW)-based bandpass filter (BPF) suffers from bulkiness that limits its application in the implementation of compact size low phase noise oscillator. Instead, in this letter, an eighth mode SIW (EMSIW) resonator-based BPF is utilized to realize a miniaturized low phase noise oscillator for <inline-formula> <tex-math notation="LaTeX">$X$ </tex-math></inline-formula>-band applications. Additionally, an equivalent circuit model of EMSIW-BPF is presented. A compact feedback-type oscillator prototype using EMSIW-BPF is designed and fabricated for the first time with a circuit area of just 1092 mm<sup>2</sup>. The experimental results of the prototype show a phase noise of −126.13 dBc/Hz at 1 MHz offset from 9.97 GHz oscillation frequency with an output power of 3.17 dBm.
Verum accent IS VERUM, but not always focus

This paper studies the occurrence of verum accent in declaratives and polar interrogatives. Verum accent exhibits two kinds of interpretational effect: (i) it requires an epistemic conflict across sentence types and (ii) it may also convey a negative speaker bias in polar interrogatives. We argue that the former effect is due to a presuppositional VERUM operator and that the latter effect arises from the possibility of said operator carrying polarity focus. Our proposal implies that verum accenting and polarity focus are two distinct phenomena that interact in interesting ways.
Al/Al2O3 metal matrix composites produced using magnetic field-assisted freeze-casting of porous ceramic structures

Al/Al2O3 metal matrix composites (MMCs) were produced by metal infiltration of porous ceramic preforms. The porous ceramic preforms were fabricated using the magnetic field-assisted freeze-casting method, resulting in vertically aligned porous channels. Preforms were prepared by freezing an Al2O3/Fe3O4-containing slurry within an applied magnetic field. Vertical alignment of the channels was facilitated by the magnetic response of the Fe3O4 in the slurry during the freezing process. After freezing and sublimation, the ceramic preforms were sintered and then infiltrated with molten A356 Al-based alloy. The mechanical properties of the resulting Al2O3/A356 MMCs were compared to those of bulk Al2O3, bulk Al-based alloy (A356), and porous Al2O3 preforms using micro-indentation testing. The indentation hardness and elastic moduli values of Al2O3/A356 MMCs showed good agreement with the predicted theoretical calculations. This study provides a new approach for the design of MMCs with controlled composition and improved mechanical characteristics.
The Relationship between Organizational Resilience and Human Resources Practices in the Hotel Industry.

This study aimed to explore the impact of organizational resilience (OR) on human resources management practices (HRMP) in the resort hotels context. Structured interviews were conducted with fourteen managers, and a pre-tested self-administrated questionnaire was used to collect the required data for this study. The questionnaire was distributed to a random sample of 300 employees working in 11 five-star hotels in the Red Sea region. The findings showed that organizational resilience has a significant relationship to HRMP. Additionally, the results revealed that hotel managers should identify and emphasize the critical role of high-performance HRMP in supporting OR strategies. The organizational resilience dimensions such as organizational culture, learning and knowledge, leadership, situation awareness, and risk management will formulate and lead the effective human resources practices. The study indicated the hotel’s ability to be resilient based on the advanced planning and development of the human resources practices. The findings suggest the hotel staff is more likely to feel secure with their jobs and are provided with training and development opportunities in resilient organizational culture. They will probably reciprocate through positive organizational behaviors, supporting organizational goals such as organizational resilience strategies. Consequently, hotels should consider these OR constructs' significant impact on the HRMP to comprehend better the practices that support creating a resilience culture in an organization.
La imagenología en el diagnóstico y la planificación de sistemas de conductos radiculares: una revisión actualizada

RESUMEN Los sistemas de conductos radiculares presentan una variada conformación morfológica para cada grupo de piezas dentarias. Diversos autores han presentado en diferentes clasificaciones su conformación anatómica y sus variantes. Tenemos los conductos principales, colaterales, laterales, secundario, accesorio, interconducto, recurrente, delta apical y cavo interradicular. La radiología actual aún no permite la visualización de todas estas estructuras; sin embargo, el uso adecuado de las técnicas imagenológicas, junto con el empleo de nuevos equipos 3D por ajustes de parámetros de adquisición con adecuados software y algoritmos, permite una precisión mayor en las imágenes lo que favorece la observación de finos detalles útiles para el diagnóstico y abordaje de los tratamientos endodónticos. El objetivo de este artículo es realizar una revisión de la literatura para identificar nuevos conceptos y herramientas imagenológicas útiles para obtener mejores diagnósticos.
Bet on Health – conference review

ABSTRACT The goal of the International Conference Bet on Health was to unite the leading researchers and practitioners so that the chief subject of this conference could be the problems related to sports, well-being, and health, and the role that local authorities/communities have when it comes to planning, implementing, and evaluating policies and practices connected to public health issues. It also served as a further interdisciplinary meeting for researchers, practitioners, and educators to present and discuss the latest trends and innovations, but also the issues and practical challenges and solutions accepted in the area of health promotion and well-being, sports, and local politics.
Pengaruh Psychological Ownership terhadap Voice Behavior

This study aims to see the direct effect of psychological ownership on voice behavior. Psychological ownership is a feeling that explains the extent to which employees feel psychologically towards the organization where they work. Meanwhile, voice behavior is the behavior of voicing information or promotional opinions that emphasize problems related to problems that have implications for the company. The research data were obtained from 223 respondents and were employees who worked at state-owned companies. The sampling technique used in this study was a combination of accidental sampling and snowball sampling. This study uses a psychological ownership scale adapted from Avey (2009) and a voice behavior scale adapted from Liang (2007). Furthermore, data analysis was performed using the Partial Least Square (PLS) method. The results of this study indicate that there is a positive and significant direct influence between psychological ownership of voice behavior. These results indicate that the higher the level of psychological ownership a person has, it will involve involvement in extra role behaviors that benefit the organization. In fact, the lower the level of psychological ownership a person has, the less interaction he has in extra role behaviors. Kata kunci: psychological ownership, voice behavior, BUMN
Intelligent hybrid automatic repeat request retransmission for multi-band Wi-Fi networks

With the increase of Wi-Fi connections and throughput, the problems posed by unreliable connection and unstable delay need to be urgently solved through advanced methods. The IEEE 802.11ax standard was designed to improve the reliability of connection and increase the throughput in dense Wi-Fi scenario where the inter-site interference becomes more serious and the spectral resources are more insufﬁcient. Furthermore, in the next generation of Wi-Fi standard IEEE 802.11be, the hybrid automatic repeat request (HARQ) and multi-band technologies will be introduced to solve the problems of unstable delay, serious interference and insufﬁcient spectrum resources. In this paper, retransmission schemes combined multi-band and hybrid automatic repeat request are deeply studied to improve the retransmission efﬁciency. Combining hybrid automatic repeat request with multi-band, this paper proposes three kinds of retransmission mode: insisting on the current frequency band (ICFB) retransmission, switching to the backup frequency band (SBFB) retransmission and concurrent retransmitting on dual-band (CRDB). Then, an intelligent selection algorithm of retransmission mode based on machine learning is designed to determine the optimal mode. Theoretical analysis and experimental results show that the proposed method can greatly improve the
The Scoring Mechanism of Players after Game Based on Cluster Regression Analysis Model

Cluster regression analysis model is an effective theory for a reasonable and fair player scoring game. It can roughly predict and evaluate the performance of athletes after the game with limited data and provide scientific predictions for the performance of athletes. The purpose of this research is to achieve the player’s postmatch scoring through the cluster regression model. Through the research and analysis of past ball games, the comparison and experiment of multiple objects based on different regression analysis theories, the following conclusions are drawn. Different regression models have different standard errors, but if the data in other model categories are put into the centroid model expression, the standard error and the error of the original model are within 0.3, which can replace other models for calculation. In the player’s postmatch scoring, although the expert’s prediction of the result is very accurate, within the error range of 1 copy, the player’s postmatch scoring mechanism based on the cluster regression analysis model is more accurate, and the error formula is in the 0.5 range. It is best to switch the data of the regression model twice to compare the scoring mechanism using different regression experiments.
Effect of coagulase-negative staphylococci on colostrum composition, properties and fatty acid profile

Background: Colostrum is the first food for mammals that should give a head start to the newborn organism. By providing the body with essential nutrients, colostrum plays an immune and immunostimulating function. Colostrum quality depends on multiple factors, including microbial effect. Widespread coagulase-negative staphylococci have a great impact on colostrum qualitative indicators. The aim of this study was to explore the effect of staphylococci on colostrum quality. Results: Physical, chemical properties and fatty acid profile of cow’s colostrum were determined. In our study we identified three pathogenic coagulase-negative Staphylococcus species in the cows’ colostrum: S. sciuri (64.29 %), S. xylosus (28.57 %) and S. warneri (7.14 %). We noted that the somatic cell count (SCC) in the affected colostrum samples wasn’t noticeably higher than that in the uninfected colostrum samples. Percentage of dry matter in infected and uninfected colostrum samples was nearly the same. Contents of fat, protein, and lactose in the studied colostrum were not significantly different. The content of butyric (С4:0) and capric (С10:0) acids was significantly higher (P<0.05) in the colostrum fat of cows infected with CNS compared to that of the uninfected animals. Conclusions: According to our research infection with coagulase-negative staphylococci negatively affects colostrum patameters primarily due to an increase in SCC, acidity and decrease in β-casein level. Moreover, significant decrease in total bacterial count in infected by CNS samples may be caused by a decrease in the level of beneficial microflora. Minor changes in fatty acid profile of fat in colostrum with CNS do not have a significant negative effect on colostrum as a whole. But in view of the fact that colostrum is intended for feeding a newborn with a "sterile" gastrointestinal tract, the presence of CNS will undoubtedly leads to a great threat to an immature organism.
THE JANUARY EFFECT AND LUNAR NEW YEAR INFLUENCES IN FRONTIER MARKETS: EVIDENCE FROM THE VIETNAM STOCK MARKET

This analysis investigates the influence of the timing of the Lunar New Year on the January effect for the Vietnam stock market. The data selected for this study is a weekly series of the market index (VN-Index) over the period from January 7, 2009 through December 26, 2018. To test for the presence of the January effect and the impact of timing of the Lunar New Year on the January anomaly, OLS and GARCH(1,1) regression models are employed. The empirical findings obtained from these models confirm the existence of the January effect during this period in the Vietnam stock market. However, the analysis reveals that the January effect is only in existence when the Lunar New Year is in February, but it is disappearing when the Lunar New Year falls in January. These findings suggest that Lunar New Year has a significant impact on the January anomaly in the Vietnam stock market providing evidence against tax loss selling while supporting other holiday and window dressing hypotheses for this widely documented seasonal phenomenon.
Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action

ABSTRACT Paracetamol (acetaminophen) is undoubtedly one of the most widely used drugs worldwide. As an over-the-counter medication, paracetamol is the standard and first-line treatment for fever and acute pain and is believed to remain so for many years to come. Despite being in clinical use for over a century, the precise mechanism of action of this familiar drug remains a mystery. The oldest and most prevailing theory on the mechanism of analgesic and antipyretic actions of paracetamol relates to the inhibition of CNS cyclooxygenase (COX) enzyme activities, with conflicting views on the COX isoenzyme/variant targeted by paracetamol and on the nature of the molecular interactions with these enzymes. Paracetamol has been proposed to selectively inhibit COX-2 by working as a reducing agent, despite the fact that in vitro screens demonstrate low potency on the inhibition of COX-1 and COX-2. In vivo data from COX-1 transgenic mice suggest that paracetamol works through inhibition of a COX-1 variant enzyme to mediate its analgesic and particularly thermoregulatory actions (antipyresis and hypothermia). A separate line of research provides evidence on potentiation of the descending inhibitory serotonergic pathway to mediate the analgesic action of paracetamol, but with no evidence of binding to serotonergic molecules. AM404 as a metabolite for paracetamol has been proposed to activate the endocannabinoid and the transient receptor potential vanilloid-1 (TRPV1) systems. The current review gives an update and in some cases challenges the different theories on the pharmacology of paracetamol and raises questions on some of the inadequately explored actions of paracetamol. List of Abbreviations: AM404, N-(4-hydroxyphenyl)-arachidonamide; CB1R, Cannabinoid receptor-1; Cmax, Maximum concentration; CNS, Central nervous system; COX, Cyclooxygenase; CSF, Cerebrospinal fluid; ED50, 50% of maximal effective dose; FAAH, Fatty acid amidohydrolase; IC50, 50% of the maximal inhibitor concentration; LPS, Lipopolysaccharide; NSAIDs, Non-steroidal anti-inflammatory drugs; PGE2, Prostaglandin E2; TRPV1, Transient receptor potential vanilloid-1
A platform methodology for smart technology within the built environment

ABSTRACT The built environment industry is facing a revolution of new digital technologies, all purporting to deliver previously unrealised value and services. However, the process for implementing these new technologies is still immature, often resulting in high-risk and high-cost implementation methodologies. In this paper, a state of the nation analysis is carried out to determine the militating factors for technology implementation within the built environment, and a new alternative non-technical platform methodology is proposed. This methodology proposes a greater focus on the use of proof-of-concepts, governance processes and regular evaluations to ensure new technologies can be implemented into buildings and cities to provide value in the short-, medium- and long-term.