Miracle-dz/UniFAR-FTUs huggingface dataset:
EmotionO+: Physiological signals knowledge representation and emotion reasoning model for mental health monitoring

Emotion is an important indicator of depressive conditions. Emotion recognition based on physiological signals such as electroencephalogram (EEG) and functional near-infrared spectroscopy (fNIRS) has gained significant attraction in healthcare domain research. Sharing of physiological signal data related to emotional response between different healthcare systems has the potential to benefit both laboratory-based healthcare research and `real-world' clinical practice. However, management and distribution of the data presents significant challenges; addressing these challenges requires advanced tools for data representation, mining and integration. In this paper we propose such a tool which contains an ontology model called EmotionO+ and rules set based on EEG, which is obtained by random forest algorithm to predict emotional state. It presents not only an effective method to enable semantic representation of the EEG and fNIRS data, but also an emotion knowledge mining tool. Results using EEG data in the eNTERFACE'06 dataset show an accuracy for our proposed model of 99.11% as compared to 97.8% for competing methods using the C4.5 algorithm. The experimental results demonstrate that the posited approach is potentially usable for early stage prediction and intervention for depressive disorders.
Tests Against Qualitative Interaction: Exact Critical Values and Robust Tests

Summary. Consider a study to evaluate treatment A with a placebo in two or more groups of patients. If treatment A is beneficial to one group of patients and harmful to another, then we say that there is qualitative interaction or crossover interaction between patient groups and the treatments. Gail and Simon (1985, Biometrics41, 361–372) developed a large‐sample procedure for this testing problem. Their test has received favorable coverage in the literature. In this article, we obtain corresponding exact finite sample results for normal error distribution and provide a table of critical values. The test statistic is similar to the familiar F‐ratio, and its p‐value is equal to a weighted sum of tail areas of F‐distributions. The computations to implement this are simple. A simulation study shows that the exact critical values provided here for normal error distribution are preferable to the asymptotic critical values for a wide range of error distributions. We also develop tests that are power robust against long‐tailed error distributions. Our robust test uses M‐estimators instead of the least squares estimators. We show that the efficiency robustness of the M‐estimator translates to power robustness of the corresponding test. Therefore, our robust tests are better if outliers are expected. A simulation study illustrates the substantial power advantages of our robust tests.
Effects on Pain of Experimentally Induced and Spontaneous Distraction

A 2-min. pain stimulus was administered twice to 56 female Ss. The stimulus was first administered prior to the experimental treatments and again with either 1 or 3 distracting treatments (Listening to a Story, Adding Aloud, or Counting Aloud) or a Control treatment. The dependent variables were Ss' self-ratings of the degree of pain experienced and the percentage of time they were thinking about the pain. 16 Ss were also interviewed post-experimentally to determine their perceptions of the experiment. During the first, but not the second, minute of pain stimulation under the experimental treatments, Listening to a Story and Adding Aloud tended to reduce the degree of pain and the percentage of time Ss were thinking about it. The post-experimental interview indicated that, during the pre-treatment pain stimulation and also under the Control treatment, Ss used their own “spontaneous” distractions to reduce pain.
Cluster Based Data Mining Technique for Identification of User Behavior

: A frameworks for identifying patterns and regularities in the pseudo anonymized Call Data Records (CDR) pertaining a generic subscriber of a mobile operator. We face the challenging task of automatically deriving meaningful information from the available data, by using an unsupervised procedure of cluster analysis and without including in the model any a priori knowledge on the applicative context. Clusters mining results are employed for understanding users' habits and to draw their characterizing profiles. A novel system for clusters and knowledge discovery called LD-ABCD, capable of retrieving clusters and, at the same time, to automatically discover for each returned cluster the most appropriate dissimilarity measure (local metric). The PROCLUS, the well know sub clustering algorithm which is used to identify the sub spaces. The data set under analysis contains records characterized only by few features and consequently to show how to generate additional fields which describe implicit information hidden in data. Also proposed an algorithm over these two techniques for searching common patterns and regularities in order to group together users characterized by a similar profile.
Fall Detection Algorithm Based on Triaxial Accelerometer and Magnetometer

Fall is a precipitous drop from a height, or from a higher position, which may be accompanied by injuries. This is one of the most dangerous and fearful situation in the elderly living. This is the reason, fast and early detection of the fall is very important to save and rescue the people and avoid the badly prognosis. In this article we are presenting a thresholdbased fall detection algorithm that processes data from common sensors in modern smart phones, such as triaxial accelerometer and magnetometer in order to detect falls. The algorithm uses Signal Vector Magnitude (SVM) peak value, base length and post-impact velocity to distinguish falls from most of daily activities. However, the SVM curve in a period produced by running is similar to a fall (a running curve can be regarded as the combination of multiple fall curves). Accordingly, residual movement is taken into account to identify running and fall. In addition, the vertical acceleration is observed to increase detection accuracy. In the experiments, the data are collected by simulating fall in four directions: forward, backward, left and right. The simulations are conducted by young people. The final experiment includes data from 120 simulated falls and 150 daily activities. Compared with previous methods, the proposed method achieves higher sensitivity and specificity.
Phenotypical and functional profiles of natural killer cells exhibiting matrix metalloproteinase‐mediated CD16 cleavage after anti‐HIV antibody‐dependent activation

Natural killer (NK) cell‐mediated antibody‐dependent cellular cytotoxicity (ADCC) has been linked to protection from HIV infection and slower progression towards AIDS. However, antibody‐dependent activation of NK cells results in phenotypical alterations similar to those observed on NK cells from individuals with progressive HIV infection. Activation of NK cells induces matrix metalloproteinase (MMP)‐mediated cleavage of cell surface CD16. In the present study we assessed the phenotype and functional profile of NK cells exhibiting post‐activation MMP‐mediated CD16 cleavage. We found that NK cells achieving the highest levels of activation during stimulation exhibit the most profound decreases in CD16 expression. Further, we observed that educated KIR3DL1+ NK cells from human leucocyte antigen (HLA)‐Bw4‐carrying donors exhibit larger decreases in CD16 expression post‐activation than the KIR3DL1− NK cell subset containing cells educated via other inhibitory receptor/ligand combinations and non‐educated NK cells. Lastly, we assessed the ex‐vivo expression of CD16 on educated KIR3DL1+ NK cells and the KIR3DL1− NK cell subset from HLA‐Bw4‐carrying HIV‐uninfected and HIV‐infected donors. Suggestive of in‐vivo activation of KIR3DL1+ NK cells during HIV infection, CD16 expression was higher on KIR3DL1+ than KIR3DL1− NK cells in uninfected donors but similar on both subsets in HIV‐infected donors. These results are discussed in the context of how they may assist with understanding HIV disease progression and the design of immunotherapies that utilize antibody‐dependent NK cell responses.
Approche clinique et anatomopathologique des lésions papillomateuses de la cavité buccale

L'augmentation de l'incidence des cancers oropharynges HPV induits depuis quelques annees necessite une vigilance dans la pratique de tout ChirurgienDentiste. Il est important de savoir reconnaitre les differentes lesions papillomateuses buccales induites par ces virus afin de pouvoir adopter une prise en charge adequate selon leur potentiel de malignite et de recidive, mais aussi en fonction des types de HPV retrouves suite a la biopsie et a l'examen anatomopathologique. La part de la prevention reste capitale dans cette prise en charge lorsque l'on connait le potentiel de contagion de ces virus. Les strategies de vaccination se doivent de rester en debat notamment par rapport a la mise en place d'une vaccination universelle (femmes et hommes).
Surface Discharges in Strong Magnetic Fields

In studying a number of processes, such as plasma confinement by magnetic field and magnetized-plasma confinement with walls, magnetic implosion of liners transiting to the plasma state during electric explosion, liner compression of magnetized plasma, magnetic-flux transfer through the insulator surface, etc., one needs to take into account surface discharges induced by magnetic-flux transfer toward the plasma or insulator (H-pressed discharge) or out of the insulator (H-thrown discharge). These discharges cause magnetic flux and energy losses (in the H-pressed discharge) or limit the energy fluxes delivered to the system and can lead to hydrogen plasma contamination with the insulator material (in the H-thrown discharge). The problem of magnetized-plasma cooling at the condensed matter/plasma interface is related to the H -pressed discharge problem. Such a problem as strong magnetic field diffusion into metal, which is very important for megagauss field generation and various applications, can also be attributed to the surface-discharge problems. If a metal is in contact with a dense magnetized plasma, surface discharges may occur near their interface, where the metal may explode and become a plasma. This paper presents the classification and the overview of the mentioned surface discharges in strong magnetic fields and considers general and specific features of these discharges.
Pentamidine-induced hyperglycemia and ketosis in acquired immunodeficiency syndrome.

To the Editor: The increasing prevalence of acquired immunodeficiency syndrome (AIDS) has been well-recognized worldwide in recent years. Pentamidine has been used for the treatment of leishmaniasis, trypanosomiasis, and Pneiimocystis carinii pneumonia (PCP) (1-3). The use of pentamidine grows in proportion to the increasing number of patients with AIDS. However, certain pentamidine-induced side effects, e.g., hypoglycemia, hyperglycemia, pancreatitis, and diabetic ketoacidosis, have been occasionally reported ( 4 6 ) . Here we report a 27-year-old bisexual man developing pancreatitis, ketosis, and eventually diabetes mellitus after pentamidine therapy.
Corticospinal signals recorded with MEAs can predict the volitional forearm forces in rats

We set out to investigate if volitional components in the descending tracts of the spinal cord white matter can be accessed with multi-electrode array (MEA) recording technique. Rats were trained to press a lever connected to a haptic device with force feedback to receive sugar pellets. A flexible-substrate multi-electrode array was chronically implanted into the dorsal column of the cervical spinal cord. Field potentials and multi-unit activities were recorded from the descending axons of the corticospinal tract while the rat performed a lever pressing task. Forelimb forces, recorded with the sensor attached to the lever, were reconstructed using the hand position data and the neural signals through multiple trials over three weeks. The regression coefficients found from the trial set were cross-validated on the other trials recorded on same day. Approximately 30 trials of at least 2 seconds were required for accurate model estimation. The maximum correlation coefficient between the actual and predicted force was 0.7 in the test set. Positional information and its interaction with neural signals improved the correlation coefficient by 0.1 to 0.15. These results suggest that the volitional information contained in the corticospinal tract can be extracted with multi-channel neural recordings made with parenchymal electrodes.
Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor

P-glycoprotein actively transports structurally unrelated compounds out of cells, conferring the multidrug resistance phenotype in cancer. Tariquidar is a potent, specific, noncompetitive inhibitor of P-glycoprotein. Tariquidar inhibits the ATPase activity of P-glycoprotein, suggesting that the modulating effect is derived from the inhibition of substrate binding, inhibition of ATP hydrolysis or both. In clinical trials, tariquidar is tolerable and does not have significant pharmacokinetic interaction with chemotherapy. In patients, inhibition of P-glycoprotein has been demonstrated for 48 h after a single dose of tariquidar. Studies to assess a possible increase in toxicity of chemotherapy and the impact of P-glycoprotein inhibition on tumor response and patient outcome are ongoing. Tariquidar can be considered an ideal agent for testing the role of P-glycoprotein inhibition in cancer.
Intuitive Storytelling Interaction: ZENetic Computer

We tried to develop an interactive system that could help us recreate our conscious selves by calling on Buddhist principles, Asian philosophy, and traditional Japanese culture through the inspirational media of ink painting, kimono and haiku. “Recreating our selves” means the process of making the consciousness of our ‘daily self’ meet that of our ‘hidden self’ through rediscovering creative resources deep within us that may have been forgotten but still resonate with vital meaning. In other words, this interactive system is based on the effort to meld our consciousness and unconsciousness in complete harmony. It is difficult to achieve this through traditional logic-based interaction. We succeeded in reaching this goal by setting as our target of scientific computing images from the above traditional Japanese media[1][3].
Fenología y brotación vegetativa de una nueva especie de Vriesea (Bromeliaceae) de Colombia en condiciones ex situ

El Jardin Botanico de Bogota (JBB) conserva en condiciones ex situ una nueva especie de bromelia epifita de Colombia del genero Vriesea, la cual fue parcialmente descrita en el 2001 por Betancur en una publicacion local; fue hallada en el municipio de Suachoque, Cundinamarca, pero hasta ahora no ha sido determinada ni publicada. La especie tiene roseta y, a la vez, es de tipo atmosferica estricta. En este estudio se describe el habitat del area donde se la encontro, los forofitos en los que se sostenia y el rango de altura en donde crecia. Tambien se describe el comportamiento de la fenologia reproductiva ex situ durante 30 semanas, los tiempos de floracion, de 1,8 semanas en promedio, la polinizacion ex situ natural, el tiempo de los frutos en desarrollo, de 3,5 semanas en promedio, y la permanencia de los frutos evidentes en el transcurso de 20,9 semanas. La maduracion y la liberacion de las semillas se produjeron entre las semanas 17 y 28 despues del inicio de la floracion. Se determino, asimismo, la brotacion vegetativa ex situ 12 meses despues del inicio de la floracion, con 1,9 brotes en promedio (0 a 3 por planta). El ciclo de vida de la especie por propagacion vegetativa debe ser superior a 16 meses y se espera recolectar las semillas para evaluarlo tambien por la via de la propagacion sexual. © 2016. Acad. Colomb. Cienc. Ex. Fis. Nat. Todos los derechos reservados.
Patient with Metastatic Process in the Skeleton of Unknown Etiology

Bearing bone involvement is a possible sign of generalization variety of cancers. In many cases the process of bearing skeletal diagnosed at the time when the primary tumor is not obvious. The task of the physician is quickly to determine whether it is a benign process or not, and diagnosis of the primary process by which then determine the further progress of therapy. The search for causative bearing shell process, alternatively the primary tumor, is often common practice in the hands of internist. Departments of Clinical Oncology do not have to have sufficient capacity for complex treatment all of newly discovered deposits skeleton whose nature does not have to be always initially clear. Therefore, in the opinion of the authors in these cases, the role of internist as a significant diagnosis very important In our article, we introduce six case reports of patients who were bearing the ambiguous process of investigation of the skeleton in our department in 2014. In accordance with the literature data were represented kidney tumor, multiple myeloma, chondrosarcoma, and in one case the origo malignant process was not found.
Mikhail Mikhaylovich Gerasimov’s authentic approach to plastic facial reconstruction

Facial reconstruction is used in paleoanthropology and the forensic sciences to predict facial appearances from dry skulls. The Russian archaeologist Mikhail Mikhaylovich Gerasimov is especially renowned for his contributions to this field; so much so, that his method defines an entire face prediction approach that delineates the theoretical and practical framework of the forensic facial reconstruction discipline. However, Gerasimov's founding method has been massively misinterpreted in the English speaking world, including the English forensic science literature. That is, Gerasimov's so-called "Russian methods" do not rely on the comprehensive construction of the facial muscles without the use of facial soft tissue thickness means as unanimously published beyond Gerasimov's manuscripts. Instead, the reverse is true: Gerasimov constructed only limited muscles – the two superficial muscles of mastication – and his method heavily depended on average soft tissue thickness values, which he twice published. While Gerasimov's hallmark Russian text, Vosstanovlenie lica po cerepu (available since 1955), clearly delineates these methods, ongoing hesitation to abandon entrenched dogma suggests that an English synopsis is timely. To avoid continuing problems of language barriers and original text scarcity, we present and illustrate Gerasimov's authentic facial reconstruction techniques in English on the basis of two primary sources: Vosstanovlenie lica po cerepu; and five, two-to-three week, one-on-one training sessions with Gerasimov in the former USSR between 1959 and 1969. While this paper is not intended to replace Gerasimov’s original works, it is intended to inspire proper consultation of his original manuscripts to correct entrenched misrepresentations; and provide insight on how Gerasimov implemented these recommendations at the work-bench, i.e., to elucidate his technique in addition to his method.
Maintenance Electroconvulsive Therapy Meeting Unmet Needs of Antipsychotics in Older Patients: A Case Report

This case report highlights problems encountered by psychiatrists when treating a 68-year-old female patient who presented with a first episode of psychosis. She suffered from constipation, an anticholinergic side effect of quetiapine and both anticholinergic and extrapyramidal side effects of olanzapine. Finally, she was able to tolerate a combination of two pharmacologically different antipsychotics namely olanzapine and aripiprazole combined with a course of ECT followed by maintenance ECT. The authors would like to highlight maintenance ECT as part of the solution to patients who find it difficult to tolerate antipsychotics. Especially when only low doses of antipsychotics can be tolerated by the patient.
Right middle-lower lobectomy by Video-assisted Thoracic Surgery (VATS).

Video-Assisted Thoracic Surgery (VATS) lobectomy is well established and performed all around the world. With growing experience with the technique, it is now generally accepted that the outcome of a VATS procedure is at least as good as, even more superior to lobectomy via traditional thoracotomy (1). Compared to open surgery, VATS may provide patients with a lower rate of morbidity and mortality, reduced pain, a shorter length of stay, better pulmonary function, and earlier return to regular activities without compromising the quality of the procedures (2).
Corrigendum Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization

The authors would like to make the following corrections to the above article. Owing to an author error, the representative images presented in Supplementary Figure 5B (right panel) and Figure 3A (middle left) were from the same file by mistake. The reused image in Supplementary Figure 5B was replaced with the corrected one from the original experiments. Note that the quantified results presented in both figures are from the original experiments and remain the same. In the Materials and methods section under the subheading ‘Analysis of subcellular localization of AP-1 dimers and proteins’, the number of cells used for quantification should be ‘50’ instead of ‘100’ (line 9, left column, page 1067). This correction applies to all quantified results of subcellular localization of AP-1 dimers and proteins throughout the paper. Note that this correction does not affect the conclusions of the article. As GFP and its variants have tendencies to form dimers when highly expressed (Tsien, 1998; Shaner et al, 2005), it was postulated by some readers that dimerization of Venus at the C-terminus of ATF2 may unmask the NES and lead to the cytoplasmic localization of ATF2-Venus. To test this possibility, the authors have performed the following two experiments. First, the authors used a monomeric form of yellow fluorescent protein mutant, Citrine(206K) (Griesbeck et al, 2001; Zacharias et al, 2002; Shaner et al, 2005), and fused Citrine(A206K) to the C-terminus of ATF2. Transient expression of the fusion protein FLAG-ATF2-Citrine(A206K) in COS1 cells resulted in a predominant cytoplasmic localization compared to Citrine(A206K) only (Supplementary Figure 7A). Second, the authors fused Venus to the N-terminus of ATF2 and examined the subcellular localization of HA-VenusATF2. Again, HA-Venus-ATF2 was also predominantly localized in the cytoplasm compared to HA-Venus (Supplementary Figure 7B). Given that the observed subcellular localization of ATF2-Citrine(A206K) and Venus-ATF2 is consistent with that of ATF2-Venus reported in the above article, the authors believe that dimerization of Venus is not the cause of the predominantly cytoplasmic localization of ATF2-Venus. These results, together with all other experimental evidence provided in the above article, strongly support the major finding that ATF2 is a nucleocytoplasmic shuttling protein and its nuclear localization depends on the dimerization with the Jun family of proteins. The authors apologize for any inconvenience caused.
MYASTHENIA GRAVIS AS AN AUTOIMMUNE DISEASE: CLINICAL ASPECTS

The factors which may be associated with the first attack or later relapses of myasthenia gravis are emotional disturbance, infection, particularly of the upper respiratory tract, and pregnancy. In this respect, and also in the sex incidence, age of onset and remittent course, there are striking resemblances with systemic lupus erythematosus (S.L.E.) and multiple sclerosis. In drawing attention to this, Simpson (1960) first pointed out that certain disorders of nonmuscular tissues may be related to the neuromuscular syndrome.