Miracle-dz/UniFAR-FTUs huggingface dataset:
Application of Bio-Nanocomposite Photoelectric Material for the Therapeutic of Cardiac Disorder: an Integration of Bio-hybrid System

For the treatment of fibrillation i.e. a cardiac disorder, wherein electrical currents are used as therapy. This disorder manifests chaotic and accelerated heart rhythm, preventing the pumping of blood to the rest the organism. In considering the remedy of this heart disease, in this study we devised therapeutics for the same through bio-nanocompositephotoelectric patches; by the application of direct immobilization of bacterial photosynthetic reaction center (RC) proteins on nanocrystalline TiO2 matrix.
The What's Next Intermittent Computing Architecture

Energy-harvesting devices operate under extremely tight energy constraints. Ensuring forward progress under frequent power outages is paramount. Applications running on these devices are typically amenable to approximation, offering new opportunities to provide better forward progress between power outages. We propose What’s Next (WN), a set of anytime approximation techniques for energy harvesting: subword pipelining, subword vectorization and skim points. Skim points fundamentally decouple the checkpoint location from the recovery location upon a power outage. Ultimately, WN transforms processing on energy-harvesting devices from all-or-nothing to as-is computing. We enable an approximate (yet acceptable) result sooner and proceed to the next task when power is restored rather than resume processing from a checkpoint to yield the perfect output. WN yields speedups of 2.26x and 3.02x on non-volatile and checkpoint-based volatile processors, while still producing high-quality outputs. Keywords-energy harvesting; intermittent computing; approximate computing;
Assimilation of Remote Sensing Data Products into Common Land Model for Evapotranspiration Forecasting

Evapotranspiration (ET), the sum of water lost to the atmosphere from the soil surface through evaporation and from plant tissues via transpiration, is a vital component of the water cycle. Accurate measurements of ET are required for the global water and energy cycles. However, ET varies in time and space and is difficult to estimate as it depends on many interacting processes. At the local scale, ET may be accurately estimated from detailed ground observations. At the regional scale sufficient ground observations will never be available and instead spatially. Remote sensing data provide us with spatially continuous information over vegetated surfaces, which supply the frequent lack of ground-measured variables and parameters required to apply the local models at a regional scale. Optical remote sensing data are strongly affected by atmospheric condition, so the uncertainty also exists in the estimation of ET with remote sensing. In this work, we develop a data assimilation scheme to improve the estimation of ET. The common land model (CoLM) is adopted as model operator to simulate the temporal variation of ET. Ensemble Kalman filter algorithm is chosen as data assimilation algorithm. The scheme can dynamically assimilate MODIS land products such as land surface temperature (LST) and leaf area index (LAI). The scheme is tested by automatic weather station (AWS) and flux tower data obtained from Xiaotangshan station in China. The results indicate that assimilating MODIS land products can improve the estimation of ET.
Artificial intelligence and big data to close the achievement gap

We observe achievement gaps even in rich western countries, such as the UK, which in principle have the resources as well as the social and technical infrastructure to provide a better deal for all learners. The reasons for such gaps are complex and include the social and material poverty of some learners with their resulting other deficits, as well as failure by government to allocate sufficient resources to remedy the situation. On the supply side of the equation, a single teacher or university lecturer, even helped by a classroom assistant or tutorial assistant, cannot give each learner the kind of one-to-one attention that would really help to boost both their motivation and their attainment in ways that might mitigate the achievement gap. This chapter argues that we now have the technologies to assist both educators and learners, most commonly in science, technology, engineering and mathematics subjects (STEM), at least some of the time. We present case studies from the fields of Artificial Intelligence in Education (AIED) and Big Data. We look at how they can be used to provide personalised support for students and demonstrate that they are not designed to replace the teacher. In addition, we also describe tools for teachers to increase their awareness and, ultimately, free up time for them to provide nuanced, individualised support even in large cohorts.
Coldwater reattachment of colonial tunicate Didemnum vexillum fragments to natural (eelgrass) and artificial (plastic) substrates in New England

The colonial tunicate Didemnum vexillum Kott, 2002, was introduced to New England in the 1980s and by 2000 it was widespread. This highly invasive species spreads by larval release and fragmentation. We tested the ability of D. vexillum fragments to reattach to natural (eelgrass Zostera marina (Linnaeus, 1753)) and artificial (plastic container) substrates during late fall and early winter. On average, 77% of D. vexillum fragments reattached to eelgrass and plastic in water temperatures between 6 and 10°C. Eelgrass appeared to facilitate D. vexillum reattachment success in early winter but this tendency should be further investigated.
Himalayan wolf and feral dog displaying mating behaviour in Spiti Valley , India , and potential conservation threats from sympatric feral dogs

This note reports a sighting of a Himalayan wolf from the trans-Himalayan region and a feral dog in a mating position in Spiti Valley, Himachal Pradesh, India. Comments on the possible reasons for the wolf’s association with feral dogs and potential harm of feral dogs to the wolf population are discussed.
Networked haptic cooperation using remote dynamic proxies

Networked haptic cooperation entails direct interaction among users as well as joint manipulation of virtual objects. To increase the realism of both types of interactions, this paper introduces remote dynamic proxies. Remote dynamic proxies are second order dynamic representations of users at the remote peer sites. They are generated according to dynamics laws and are controlled by the user whom they represent through a virtual coupler. Hence, they move in a physically intuitive manner and do not suffer from position discontinuities due to network packet transmission limitations. The remote dynamic proxies are integrated into a distributed control architecture for networked haptic cooperation. An experimental comparison of the new controller to two recently proposed controllers demonstrates smoother rendering of contact between users, as well as stable cooperation for larger network delays.
1 . 1 A tea-break puzzle

We show a deterministic simulation (or lifting) theorem for composed problems f ◦ Eqn where the inner function (the gadget) is Equality on n bits. When f is a total function on p bits, it is easy to show via a rank argument that the communication complexity of f ◦ Eqn is Ω(deg(f) · n). However, there is a surprising counter-example of a partial function f on p bits, such that any completion f ′ of f has deg(f ′) = Ω(p), and yet f ◦ Eqn has communication complexity O(n). Nonetheless, we are able to show that the communication complexity of f ◦ Eqn is at least D(f) · n for a complexity measure D(f) which is closely related to the AND-query complexity of f and is lower-bounded by the logarithm of the leaf complexity of f . As a corollary, we also obtain lifting theorems for the set-disjointness gadget, and a lifting theorem in the context of parity decision-trees, for the NOR gadget. As an application, we prove the first tight lower-bound for the deterministic communication complexity of the natural Gap-Equality problem, where Alice and Bob are each given p-many n-bit strings, with the promise that either 3 4 of them are equal or 3 4 of them are different, and they wish to know which is the case. We show that the complexity of this problem is Θ(p · n).
The pathophysiology of respiratory chain dysfunction

5 List of publications 7 Abbreviations 10 Background 11 Mitochondrial Genetics 11 Mitochondria 11 Evolution of Mitochondria 13 Regulation of mitochondrial fusion and fission 14 Structure, gene content and organization of mammalian mtDNA 15 Transcription of mammalian mtDNA 18 Replication of mammalian mtDNA 20 Mitochondrial transciption factor A (TFAM) 22 Transmission and segregation of mammalian mtDNA 23 Regulation of mitochondrial gene expression and biogenesis 24 Mitochondrial bioenergetics and ROS formation 26 The respiratory chain 26 Generation of ROS by the respiratory chain 32 Antioxidant defense mechanisms 34 Mitochondrial uncoupling proteins and their role in energy expenditure and control of ROS homeostasis 37 Mitochondrial regulation of apoptosis 39 Free radical theory of aging 44 Respiratory chain diseases 46 Respiratory chain diseases 46 Mitochondrial diabetes 50 ROS formation in respiratory chain deficient cells 51 Metabolic alterations and cell death in respiratory chain deficient cells 53 Mouse models for respiratory chain disease 55 Aims of this study 59
Layout Optimization and Promotional Strategies Design in a Retail Store based on a Market Basket Analysis

Retail transactional data is a rich source of information offering new dimensions for company’s competition. The challenge is to turn data into useful insights with business value. One widely used technique for analyzing transactional data is Market Basket Analysis (MBA), which is a data mining technique that studies what customers’ are buying together. Thus, MBA is a contingency study and not a correlation analysis. In this paper we present a case study for analyzing retail transactional data using MBA and use the results as a prescriptive model for sell floor optimal design and for guiding the design of related in-store promotional strategies. Keywords– Market Basket Analysis, Affinity Analysis, Sell Floor Layout Optimization, In-store Promotional Strategies. Digital Object Identifier (DOI):http://dx.doi. org/10.18687/LACCEI2016.1. 1.307 ISBN: 978-0-9822896-9-3
Honeycomb‐Like Spherical Cathode Host Constructed from Hollow Metallic and Polar Co9S8 Tubules for Advanced Lithium–Sulfur Batteries

The practical application of lithium‐sulfur (Li‐S) batteries remains remote because of rapid capacity fade caused by the low conductivity of sulfur, dissolution of intermediate lithium polysulfides, severe volumetric expansion, and slow redox kinetics of polysulfide intermediates. Here, to address these obstacles, a new sulfiphilic and highly conductive honeycomb‐like spherical cathode host constructed from hollow metallic and polar Co9S8 tubes is designed. Co9S8 can effectively bind polar polysulfides for prolonged cycle life, due to the strong chemisorptive capability for immobilizing the polysulfide species. The hollow structure, as the sulfur host, can further prevent polysulfide dissolution and offer sufficient space to accommodate the necessary volume expansion. Well‐aligned tubular arrays provide a conduit for rapid conduction of electrons and Li‐ions. More importantly, the experimental results and theoretical calculations show that Co9S8 plays an important catalytic role in improving the electrochemical reaction kinetics. When used as cathode materials for Li–S batteries, the S@Co9S8 composite cathode exhibits high capacity and an exceptional stable cycling life demonstrated by tests of 600 cycles at 1 C with a very low capacity decay rate of only ≈0.026% per cycle.
Low-frequency sound radiated by a nonlinearly modulated wavepacket of helical modes on a subsonic circular jet

A possible fundamental physical mechanism by which instability modes generate sound waves in subsonic jets is presented in the present paper. It involves a wavepacket of a pair of helical instability modes with nearly the same frequencies but opposite azimuthal wavenumbers. As the wavepacket undergoes simultaneous spatial–temporal development in a circular jet, the mutual interaction between the helical modes generates a strong three-dimensional, slowly modulating ‘mean-flow distortion’. It is demonstrated that this ‘mean field’ radiates sound waves to the far field. The emitted sound is of very low frequency, with characteristic time and length scales being comparable with those of the envelope of the wavepacket, which acts as a non-compact source. A matched-asymptotic-expansion approach is used to determine, in a self-consistent manner, the acoustic field in terms of the envelope of the wavepacket and a transfer factor characterizing the refraction effect of the background base flow. For realistic jet spreading rates, the nonlinear development of the wavepacket is found to be influenced simultaneously by non-parallelism and non-equilibrium effects, and so a composite modulation equation including both effects is constructed in order to describe the entire growth–attenuation–decay cycle. Parametric studies pertaining to relevant experimental conditions indicate that the acoustic field is characterized by a single-lobed directivity pattern beamed at an angle about 45°–60° to the jet axis and a broadband spectrum centred at a Strouhal number St ≈ 0.07–0.2. As the nonlinear effect increases, the radiation becomes more efficient and the noise spectrum broadens, but the gross features of the acoustic field remain robust, and are broadly in agreement with experimental observations.
Syddansk Universitet Internet-based vs . face-to-face cognitive behavior therapy for psychiatric and somatic disorders an updated systematic review and meta-analysis

During the last two decades, Internet-delivered cognitive behavior therapy (ICBT) has been tested in hundreds of randomized controlled trials, often with promising results. However, the control groups were often waitlisted, care-as-usual or attention control. Hence, little is known about the relative efficacy of ICBT as compared to face-to-face cognitive behavior therapy (CBT). In the present systematic review and meta-analysis, which included 1418 participants, guided ICBT for psychiatric and somatic conditions were directly compared to faceto-face CBT within the same trial. Out of the 2078 articles screened, a total of 20 studies met all inclusion criteria. Results showed a pooled effect size at post-treatment of Hedges g = . 05 (95% CI, −.09 to .20), indicating that ICBT and face-to-face treatment produced equivalent overall effects. Study quality did not affect outcomes. While the overall results indicate equivalence, there have been few studies of the individual psychiatric and somatic conditions so far, and for the majority, guided ICBT has not been compared against face-to-face treatment. Thus, more research, preferably with larger sample sizes, is needed to establish the general equivalence of the two treatment formats. Introduction The first treatment studies on Internet-delivered cognitive behavior therapy (ICBT) were carried out in the late 1990s (Andersson, Carlbring, & Lindefors, 2016). They were designed to mirror face-to-face treatments in terms of content and length. Since
An Urban Regeneration Regime in China: A Case Study of Urban Redevelopment in Shanghai's Taipingqiao Area

This article investigates Taipingqiao urban redevelopment projects in Shanghai that have conserved the traditional 'Shikumen' architectural form with the goal of exploring the driving-forces behind Shanghai's spatial restructuring and to shed light on the new mechanisms for public-private partnership evolving in China. A model called a 'rent gap seeking regime' (RGSR) is proposed to explain the mechanisms behind China's urban redevelopment. It is found that the logic of capital accumulation has dominated the reshaping of Shikumen's spatial forms and has been transformed into symbolic real estate values. It is argued that a pro-growth coalition between district government and foreign capital emerged during this process of urban restructuring; the paper analyses the features of how this coalition exercises power. Finally, based on empirical research, the paper engages Western regime analysis in a theoretical dialogue.
Geodynamic evolution of Upper Cretaceous Zagros ophiolites: formation of oceanic lithosphere above a nascent subduction zone

Abstract The Zagros fold-and-thrust belt of SW Iran is a young continental convergence zone, extending NW–SE from eastern Turkey through northern Iraq and the length of Iran to the Strait of Hormuz and into northern Oman. This belt reflects the shortening and off-scraping of thick sediments from the northern margin of the Arabian platform, essentially behaving as the accretionary prism for the Iranian convergent margin. Distribution of Upper Cretaceous ophiolites in the Zagros orogenic belt defines the northern limit of the evolving suture between Arabia and Eurasia and comprises two parallel belts: (1) Outer Zagros Ophiolitic Belt (OB) and (2) Inner Zagros Ophiolitic Belt (IB). These belts contain complete (if disrupted) ophiolites with well-preserved mantle and crustal sequences. Mantle sequences include tectonized harzburgite and rare ultramafic–mafic cumulates as well as isotropic gabbro lenses and isolated dykes within the harzburgite. Crustal sequences include rare gabbros (mostly in IB ophiolites), sheeted dyke complexes, pillowed lavas and felsic rocks. All Zagros ophiolites are overlain by Upper Cretaceous pelagic limestone. Limited radiometric dating indicates that the OB and IB formed at the same time during Late Cretaceous time. IB and OB components show strong suprasubduction zone affinities, from mantle harzburgite to lavas. This is shown by low whole-rock Al2O3 and CaO contents and spinel and orthopyroxene compositions of mantle peridotites as well as by the abundance of felsic rocks and the trace element characteristics of the lavas. Similarly ages, suprasubduction zone affinities and fore-arc setting suggest that the IB and OB once defined a single tract of fore-arc lithosphere that was disrupted by exhumation of subducted Sanandaj–Sirjan Zone metamorphic rocks. Our data for the OB and IB along with better-studied ophiolites in Cyprus, Turkey and Oman compel the conclusion that a broad and continuous tract of fore-arc lithosphere was created during Late Cretaceous time as the magmatic expression of a newly formed subduction zone developed along the SW margin of Eurasia.
Study of the effects of the antifungal defensin Psd1 in Candida albicans using atomic force microscopy and flow cytometry

viii Resumo . ix List of figures and tables . xii Abbreviations, acronyms and symbols . xiv Introduction . 1 1. Candida albicans . 1 1.1. Candida albicans pathogenicity . 1 1.2. Fungal targets for antifungal drugs . 2 1.3. Apoptosis in yeast . 4 2. Antimicrobial Peptides . 5 3. Models of membrane activity – mechanism of action of AMPs . 6 4. Resistance . 8 5. Defensins . 9 5.1. Immunomodulatory function . 10 5.2. Pisum sativum defensin 1 . 11 Aims and Goals . 12 Methodology . 13 1. Atomic Force Microscopy . 13 2. Flow Cytometry . 16 Materials and Methods . 19 1. Cell Suspension . 19 2. Antifungal susceptibility – minimal inhibitory concentration determination. 19 3. Atomic Force Microscopy (AFM). 20 3.1. Imaging . 20 3.2. Force Spectroscopy . 20 4. Flow Cytometry . 21 Results . 22 1. Susceptibility of planktonic C. albicans cells to Amph B, FCZ and Psd1 . 22 2. Amph B, FCZ and Psd1 cause morphological alterations in C. albicans . 22 3. C. albicans suffers an increase in surface roughness after treatment with Amph B, FCZ or Psd130 4. C. albicans loses stiffness after treatment with Amph B, FCZ or Psd1 . 31 4.1. Young's Modulus determination . 32
Colonization of a new habitat : The case of the Dead Sea sinkholes – preliminary observations

רקחמ רמאמ Research article Negev, Dead Sea and Arava Studies 6 (3), 74–89 (2014) 89 –74 ,(3) 6 הברעהו חלמה םי ,בגנה ירקחמ
Assessing the potential for tertiary nitrification in sub-surface flow constructed wetlands

The challenge of how to maintain or improve wastewater treatment performance without causing an excessive increase in energy or costs is increasingly focussed towards ammonia. On small sewage treatment works, solutions have historically been energy intensive: to divert waste to a larger plant, add a polishing step to the end of the process flow sheet or upgrade and replace upstream processes. Constructed wetlands (CWs) offer a low energy alternative to meet these challenges. This review explores oxygen transfer theory; nitrification performance of existing CW systems, and the key affecting factors to be considered when implementing the technology for tertiary treatment upgrades. Future perspectives include the use of artificial aeration and greater consideration of vertical sub-surface flow systems as they achieve the nitrification capacity in a smaller footprint than horizontal flow systems and, where suitable hydraulics permit, can be operated under very low energy demand.
Clinical and prognostic importance of XIAP and USP 8 in advanced stages of non-small cell lung cancer

Results: The median serum XIAP level of the patients and the control group showed no significant difference. USP8 level was higher in patients than in controls (p<0.0001). In univariate analysis, there was no significant relationship between XIAP and USP8 serum levels and age, sex, performance status, weight loss, stage of disease, histopatological type and response to chemotherapy. Response to chemotherapy did not differ between the high and low XIAP and USP8 groups . There was no significant difference in progression-free survival (PFS) (p=0.432 and p=0.50, respectively) and overall survival (OS) (p=0.989 and p=0.90, respectively) between the low and high XIAP and USP8 groups. Conclusion: No relationship was found in serum XIAP and USP8 levels with clinical parameters, response to chemotherapy, PFS and OS in patients with advanced stages of NSCLC.