Miracle-dz/UniFAR-FTUs huggingface dataset:
Efektivitas Ekstrak Kulit Manggis (Garcinia mangostana L.) 100% Dalam Membersihkan Smear Layer Pada Dentin Mahkota The effectiveness of 100% Mangosteen Pericarp Extract(Garcinia mangostana L.)on Removing Smear Layer of Crown Dentine

Smear layer is a layer that is formed when dentine is prepared. Smear layer can disturb the adhesion of restoration material to dentine, therefore it needs cleansing using dentine conditioner. One of cleansing materials for smear layer is 10% poliacrylic acid. To achieve optimal clean result of cavity wall preparation, it is necessary to use natural materials as alternative and may minimize the side effect, like mangosteen pericarp extract (Garcinia mangostana L.). This study aimed atknowing the ability of 100% mangosteen pericarp extract on removing smear layer of cavity wall of tooth prepared. This study is experimental laboratory using 10 samples of first maxillary premolar prepared with circle-shaped class 1 cavity design with 2 mm diameter, 2 mm in depth one third from the center of labial surface. 5 samples were applied with 10% poliacrylic acid, the 5 other samples were applied 100% mangosteen pericarp extract, allowed for 20 seconds and irrigated with sterile aquadest and dried. The samples were examined for their cleanliness from smear layer using SEM with 3500x magnifying. The result showed that the cleanliness of smear layer applied with 10% poliacrylic acidwas lower compared to the group with 100% mangosteen pericarp extract. Statistically, there were no significant differences between these groups (p=0,065 ; p > 0.05).
Sgs1 BLM independent role of Dna2 DNA2 nuclease at DNA double strand break is inhibited by Nej1 XLF

The two major pathways of DNA double strand break (DSB) repair, non-homologous end-joining (NHEJ) and homologous recombination (HR), are highly conserved from yeast to mammals. Regulated 5’ DNA end resection is important for repair pathway choice and repair outcomes. Nej1 was first identified as a canonical NHEJ factor involved in stimulating the ligation of broken DNA ends and, more recently, it was shown to be important for DNA end-bridging and inhibiting Dna2-Sgs1 mediated 5’ resection. Dna2 localizes to DSBs in the absence of Sgs1 through interactions with Mre11 and Sae2 and DNA damage sensitivity is greater in cells lacking Dna2 nuclease activity compared to sgs1∆ mutants. Dna2-Sae2 mediated 5’ resection is down-regulated by Nej1, which itself interacts with Sae2. The resection defect of sae2 ∆ and the synthetic lethality of sae2 ∆ sgs1 ∆ are reversed by deletion of NEJ1 and dependent on Dna2 nuclease activity. Our work demonstrates the importance of Nej1 in inhibiting short-range resection at a DSB by Dna2-Sae2, a critical regulatory mechanism that prevents the formation of genomic deletions at the break site.
Duisenberg School of Finance- For leaders in Finance Master Thesis in Finance Search for Alpha- EMA weighted momentum based approach By

By exploiting momentum strategy; “buying winner portfolio and selling portfolio” this research papers investigates the evidence against the strong form of efficiency which claims that one cannot earn excess return with historical information and excess return if any, is mere compensation of excess risk taking behavior. The study undergone during the comprehensive research reveals the evidences of the weak form of efficiency and presence of meager weak momentum effect with holding period 1 month and in rest of the cases, on inclusion of transaction cost, such strategy will perform worse than buy and hold strategy. The trading strategy has been tested on S&P Nifty between periods of 2000 to 2013. The significance of this period is that it includes both bull and bear era. In fact, period between 2002 and 2007 was predominantly a bull era backed by strong economic growth whereas period between 2007 and 2012 was period of extreme distress with economic activity contracting globally. Research focused on periods with such structural breaks ensures the obtained results are significant and not merely a fluke. Noteworthy, the results obtained are expected as per general weak efficient market hypothesis and are contrarian to momentum effect by Narasimhan Jegadeesh for midlongterm; and to De Bondt and Thaler’s contrarian effect. In addition, the author in his research has tried to analyze the causes of momentum and contrarian effects in general and results are analyzed from the perspective of behavioral finance. Also, the paper unfolds the comprehensive analysis of the calendar effect in the markets that might contribute to the weak momentum effect observed in the result.
Impacts and uncertainties of climate change on stream flow of the Bilate River (Ethiopia), using a CMIP5 general circulation models ensemble

The impact and uncertainty of climate change on stream flow of the Bilate River Watershed was assessed. Ensemble of 20 Coupled Model Intercomparison Project Phase 5 (CMIP5) general circulation models (GCMs) under two Representative Concentration Pathways and six GCM structures were selected to form 24 future climate scenarios for the watershed. Soil and Water Assessment Tool (SWAT) model was selected to simulate stream flow of the watershed. The respective statistical results of the coefficient of determination (R2), Nash-Sutcliffe coefficient (NSE) and percent bias (PB) are 0.79, 0.78 and 0.56 for calibration period and 0.64, 0.60 and -21.7 for validation period which show that the model predicted the stream flow reasonably. The annual stream flow increased progressively throughout the century for all time periods. The increases under RCP 8.5 scenario are the larger compared to RCP 4.5 scenarios, approximately 42.42% during the 2080s period. The six GCMs selected to see the uncertainties related to GCMs suggest that the river flow will change by small amounts of -6.18 to 7.83% change compared with the baseline. The simulated runoff depended on the projected amount of rainfall embedded in the GCM structures selected to simulate the future climate and less dependent on the local temperature increment. Key words: Climate change, Bilate River watershed, stream flow, soil and water assessment tool (SWAT), uncertainty.
The value of the Global Registry of Acute Coronary Events and Gensini scores in predicting long-term outcomes in Vietnamese patients with non-ST-elevation acute coronary syndrome

Introduction: Patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) should undergo risk stratification as soon as possible after their presentation. Early risk satisfaction provides good prognosis for patients as well as better decision for reperfusion therapy. The aim of this study is to find a correlation between the Global Registry of Acute Coronary Events (GRACE) risk score and severity of coronay artery disease assessed by Gensini score score and compare the value of GRACE and Gensini scores in predicting the long-term outcomes in patients with NSTE-ACS. Methods: A total of 220 patients with NSTE-ACS who underwent coronary angiography were enrolled in our study. The Gensini score was used to assess the severity of coronary artery disease. According to the GRACE score, the patients were grouped into low, intermediate and high groups. After 30 months of follow-up, 20 patients died. Results: The mean Gensini scores were 11.8 ± 11.5, 27.4 ± 30.9, and 42.9 ± 29.7 in the low, intermediate and high-risk groups, respectively. The GRACE scores and Gensini score had a moderate positive correlation (rho = 0.522, p < 0.001). The survival rates showed a less rapid deterioration from the low to high GRACE groups (P = 0.013) than when classified according to their Gensini tertiles (P = 0.02). Area under the ROC curve was statistically significant for both scores, but area of the GRACE risk score (0.71; 95% Cl = 0.60 - 0.82) was higher than that the Gensini risk score (0.66; 95% Cl = 0.53 – 0.80). Conclusion: Our study revealed that the Gensini score had a positive and significant relationship with the GRACE score in patients with NSTE-ACS. The GRACE score had a more value in predicting long-term outcomes in patients with NSTE-ACS.
Computational approach to increasing the packing fraction of amorphous powders

The powder packing behaviour of Fe-based amorphous powders was experimentally monitored and compared with values predicted using the Desmond model and a simulation based on the discrete element method. Powders with different sizes were mixed in various ratios to produce a tri-modal distribution. The simulation results revealed the cohesive force of the powder in terms of the angle of repose and were in agreement with the experimental results. However, the packing behaviour derived from the theoretical model deviated from the experimental results because the interaction among the powder was not considered in the former. Furthermore, the packing fractions for different mixing ratios were investigated through an artificial intelligence framework to determine the optimal mixing ratio. This ratio was validated experimentally and determined to be approximately 8.97% higher than that for the monodisperse large powder case.
The use of wind turbines and the problem of icing

The world’s energy demand is increasing. Wind energy plays an important role in meeting this demand. Investments in wind energy have been increasing in recent years. It can be said that the source of wind energy will be unlimited since there will be wind as long as there is sun. Most governments meet a large energy need by generating electricity from wind. At the end of 2019, the total amount of electricity generated from wind was 650 GW. Wind energy capacity is increasing with offshore wind pairs. Offshore wind turbines are a new field and research studies are ongoing. Wind turbines have the capacity to be installed anywhere in the world, and each government will have its own energy source. There is a problem of icing in wind power plants installed in cold climates. With this problem, efficiency in wind turbines decreases. Many methods have been found and developed in studies on icing problems. In this article, wind turbines were investigated, states’ perspectives on wind energy, developments and investments in wind energy, and the problem of icing were examined. Many articles in the literature have been reviewed and a solution to the icing problem of wind turbine blades has been sought.
A comparison of a gradient boosting decision tree, random forests, and artificial neural networks to model urban land use changes: the case of the Seoul metropolitan area

ABSTRACT This study compares the performance of gradient boosting decision tree (GBDT), artificial neural networks (ANNs), and random forests (RF) methods in LUC modeling in the Seoul metropolitan area. The results of this study showed that GBDT and RF have higher predictive power than ANN, indicating that tree-based ensemble methods are an effective technique for LUC prediction. Along with the outstanding predictive performance, the DT-based ensemble models provide insights for understanding which factors drive LUCs in complex urban dynamics with the relative importance and nonlinear marginal effects of predictor variables. The GBDT results indicate that distance to the existing residential site has the highest contribution to urban land use conversion (30.4% of the relative importance), while other significant predictor variables were proximity to industrial and public sites (combined 32.3% of relative importance). New residential development is likely to be adjacent to existing residential sites, but nonresidential development occurs at a distance (about 600 m) from such sites. The distance to the central business district (CBD) had increasing marginal effects on residential land use conversion, while no significant pattern was found for nonresidential land use conversion, indicating that Seoul has experienced more population suburbanization than employment decentralization.
After-Hours Learning

Many initiatives have focused on attracting girls and young women (K-12 or college) to computer science education. However, professional women who never learned to program have been largely ignored, despite the fact that such individuals may have many opportunities to benefit from enhanced skills and attitudes about computer programming. To provide a convenient learning space for this population, we created and evaluated the impacts of a nine-week web development workshop that was carefully designed to be both comfortable and engaging for this population. In this article, we report how the professionals’ attitudes and skills grew over the course of the workshop and how they now expect to integrate these skills and attitudes into their everyday lives.
Unique and Combined Contribution of Peer Victimization and Maltreatment in Childhood to Young Adults’ Anxiety, Depression, and Suicidality: A Cross-Sectional Study

BackgroundChild maltreatment and peer victimization are known to be major risk factors for depression and suicidal behavior. Furthermore, child maltreatment increases the risk for victimization by peers. Our objective was to distinguish the contribution of maltreatment by parents and peer victimization to mental health problems in young adulthood. Specifically, we tested whether peer victimization alone or in combination with parental maltreatment before 18 years was associated with anxiety, depression, and suicidal thoughts and behaviors at age 21 years.MethodsWe used data collected in the i-Share (internet-based students’ health research enterprise) study in France from February 2013 to September 2019 (N = 2271 participants). We conducted multinomial and binary logistic regression analyses to assess the unique and cumulative contribution of peer victimization and parental maltreatment with anxiety, depression, and suicidality. ResultsAlmost one third of students (28.8%) reported at least one mental health problem; 29.8% reported peer victimization only; 7.5% reported parental maltreatment only; and 10.3% reported both maltreatment and victimization. In multivariate models, compared to participants who did not experience maltreatment or peer victimization, those who experienced peer victimization only were more likely to present anxiety (aOR: 1.90; 95% CI: 1.50-2.40), depression (aOR: 1.95; 95% CI: 1.46-2.60), or suicidal ideation without (aOR: 1.62; 95% CI: 1.26-2.09) and with attempt (aOR: 2.70; 95% CI: 1.51-4.85). Similar associations were observed for those who were maltreated only. Those experiencing both maltreatment and peer victimization were at increased risk for depression (aOR: 2.63; 95% CI: 1.79-3.86) and for suicidal ideation with (aOR: 9.19; 95% CI: 4.98-16.92) and without attempt (aOR: 2.64; 95% CI: 1.86-3.76). ConclusionsIndividual and combined exposure to parental maltreatment and peer victimization in childhood or adolescence was associated with increased risk for anxiety, depression and suicidal behaviors. Peer victimization seems to have a specific role on mental health disorders not otherwise explained by polyvictimization. Since peer victimization is a frequent and evitable child abuse type, the findings have implications for policies to prevent and deal with.
Photovoltaic failure and degradation modes

The extensive photovoltaic field reliability literature was analyzed and reviewed. Future work is prioritized based upon information assembled from recent installations, and inconsistencies in degradation mode identification are discussed to help guide future publication on this subject. Reported failure rates of photovoltaic modules fall mostly in the range of other consumer products; however, the long expected useful life of modules may not allow for direct comparison. In general, degradation percentages are reported to decrease appreciably in newer installations that are deployed after the year 2000. However, these trends may be convoluted with varying manufacturing and installation quality world‐wide. Modules in hot and humid climates show considerably higher degradation modes than those in desert and moderate climates, which warrants further investigation. Delamination and diode/j‐box issues are also more frequent in hot and humid climates than in other climates. The highest concerns of systems installed in the last 10 years appear to be hot spots followed by internal circuitry discoloration. Encapsulant discoloration was the most common degradation mode, particularly in older systems. In newer systems, encapsulant discoloration appears in hotter climates, but to a lesser degree. Thin‐film degradation modes are dominated by glass breakage and absorber corrosion, although the breadth of information for thin‐film modules is much smaller than for x‐Si. Copyright © 2017 John Wiley & Sons, Ltd.
TRANSDERMAL DELIVERY OF DESMOPRESSIN ACETATE FROM WATER-IN-OIL NANO/SUBMICRON EMULSION SYSTEMS

Desmopressin acetate is a potent synthetic peptide hormone. A more acceptable route of Desmopressin acetate is a potent synthetic peptide hormone. That is administered via parenteral, intranasal, and oral routes. A more acceptable route of administration with potentially good bioavailability could be offered by transdermal delivery. The present work reports on the development of water-in-oil (w/o) microemulsions for the transdermal administration of desmopressin acetate. A water-in-oil nano/submicron emulsions for transdermal administration of desmopressin developed. Its skin penetration profiles determined using Franz-diffusion cell. Pseudo-ternary phase diagrams for emulsion regions constructed. Effects of hydrophilic-lipophilic balance (HLB), ratio of surfactants and co-surfactant mixture to oil phase (Smix/oil), and ratio of surfactants to co-surfactant (S/Cs) on skin flux evaluated. Skin flux was increased when S/Cs and Smix/oil were decreased, and HLB was increased. Optimized formulation was obtained as: HLB=8, S/Cs=3 and Smix/oil=5.4, with average particle size of 69nm. The optimized nano/submicron emulsions increased desmopressin skin flux 4.45 fold relative to drug solution.
Acousto-optic Design to Measure Glucose Level for Diabetic Patients Non-invasively

Due to increasing numbers of diabetic patient and the dangerous of life threatening some cases that need a continuous monitoring of the glucose level. Recently the demand for a non-invasive system is raised. This study aims to design an optimized noninvasively acousto-optic monitoring glucose system device to limit the possibility of secondary risk that raised from infection of invasive blood sample or from glucose fluctuation due to fewer number of glucose checking. There is a great demand for painless, glucose sensitive and commercial equipment. The current design methodology depends on the liaison between the penetrated electromagnetic wave through tissue and glucose level based on acousto-optic interaction technique. We can exceed the complication of acousto-optic design for biological tissue testing practically, the complication are with light and sound penetration, heat generation, and others. This work study both of Raman-Nath and Bragg interaction methods of acousto-optic technique with their advantages and disadvantages, with the possibility to reach the optimization in sensing blood glucose.
Understanding British and Danish sailing tourism markets: an analysis based on Kano's Evaluation Matrix

ABSTRACT Sailing tourism is deemed to be a significant tourism activity and economic contributor. Without an adequate assessment of the impact of marina attributes on tourist satisfaction, sailing destinations may not be able to map out successful marketing strategies and effectively increase destination attractiveness. Therefore, this research examined the marina attributes that impact the satisfaction of British and Danish sailing tourists, by adopting independent-samples t-tests, Kano's Evaluation Matrix (KEM) analysis, and the calculation of customer satisfaction coefficients. This research found differences between the British and Danish sailing tourists’ perceptions of marina attributes. The British sailing tourists place greater importance to safe sailing experience, while the Danish appear to place more emphasis on the service amenities and recreational opportunities. The findings of this research are of benefit to the sailing industry and destination communities as it gives an insight into the factors that are necessary to provide higher levels of tourist satisfaction and consequent improvements to socioeconomic benefits from sailing tourism.
CO emissions from degrading plant matter.

CO emissions from degrading deciduous leaf and grass matter have been investigated in laboratory and field measurements. CO emissions are induced both photochemically and thermally. Photochemical CO production can be described by a 2nd-order polynomial in light intensity and exhibits a hysteresis effect, not previously reported. Humid material showed higher CO emissions than dry material. A preliminary, relative action spectrum for the photochemically induced CO emissions is presented. Although UV irradiation caused most of the CO production, visible light also caused up to 40% of the emissions. We propose a cleavage of the cellulose chain as the important step prior to CO production. Thermal CO emissions from degrading plant material obey an Arrhenius type equation (presented for several species in this paper), but emissions are lower than those induced photochemically. During our field measurements on dry grasses in a South African savanna we found a strong influence of incident radiation intensity and temperature on measured CO fluxes. Solely photochemical CO production from the grasses is calculated by subtraction of soil fluxes and thermally induced grass CO emissions from the total CO emissions. CO emissions and hysteresis differ between the grasses investigated and may be interpreted by the grass' colour and their architecture. Deposition of CO on the soils was much lower than CO emission from the dry grasses during daytime. Nighttime data show that possible thermal CO production from the grasses may partially compensate for CO deposition on the soils for several hours after sunset depending on temperature. DOI: 10.1034/j.1600-0889.1999. t01-4-00003.x
Evaluation of Maximum Biting Force in Two Different Attachment Systems (Bollard vs. Ball and Socket) Retaining Mandibular Overdenture: A Split-mouth Design

AIM: The study was conducted to evaluate maximum biting force (MBF) in two different attachment systems (bollard a vs. ball and socket attachment) retaining mandibular overdenture using a split-mouth design. SUBJECTS AND METHODS: Twelve completely edentulous patients received complete dentures and after adaption of the patient with the new denture, 24 implants were inserted in the canine region using two-stage surgical technique and conventional loading protocol. Six patients received the Bollard attachment at the right side and the Ball and Socket at the left side. Moreover, the other six patients received the bollard attachment at the left side and the ball and socket attachment at the right side. Each patient was treated according to split-mouth design. Insertion of each of the attachment type was assigned randomly. Using occlusal force meter instrument, MBF was measured immediately after loading (0), after 6 months (6), and after 12 months (12). RESULTS: Significant statistical differences (p < 0.05) were obvious in in MBF between Attachment (1) and Attachment (2) immediately after loading (0 months), after 6 months (6) and after 12 months (12) follow-up visits. CONCLUSION: Mandibular implant retained overdenture received Bollard abutment that retained with the denture by the help of resilient liner “Retention.sil”* without housing have higher biting forces than mandibular implant retained overdenture with ball abutment where the plastic house was picked up by monomer free self-cured acrylic resin. Edited by: Aleksandar Iliev Citation: Elbeheiry RTK, Mohamed GF, Badr AMI. Evaluation of Maximum Biting Force in two different attachment systems (Bollard vs. Ball and Socket) Retaining Mandibular Overdenture: A Split-mouth Design. Open Access Maced J Med Sci. 2021 Mar 08; 9(D):47-53. https://doi.org/10.3889/oamjms.2021. 5829