Miracle-dz/UniFAR-FTUs huggingface dataset:
A consistent zero-configuration GPS-Like indoor positioning system based on signal strength in IEEE 802.11 networks

After the success of Global Positioning System (GPS) which provides precise positioning in open-sky areas having reliable satellites visibility, significant research is currently focused on providing similar systems for indoors in which satellites are poorly visible or unavailable. This paper introduces a GPS-like indoor positioning system based on Received Signal Strength (RSS) of the popular IEEE 802.11 networks (WiFi). Unlike current RSS-based indoor systems, the proposed system doesn't require time-consuming offline radio survey or prior-knowledge about the area or new hardware. Similar to GPS, the system consists of three segments; network segment (WiFi), control segment, and user segment. RSS observations are exchanged periodically between network segment and control segment. The control segment uses a novel hybrid propagation modeling (PM) technique using logarithmic decay model augmented by a nonlinear Gaussian Process Regression (GPR) that models RSS residuals that cannot be modeled by the traditional logarithmic decay models indoors. PM parameters are periodically estimated and sent to each AP. The user segment receives RSS and PM parameters from APs and performs trilateration weighting each observation by a variance calculated by GPR. Real experiments in indoor area show reliable meter accuracy comparable to those obtained from similar RSS-based indoor methods that uses offline time-consuming training such as fingerprinting.
Full Immersion in the Mainstream: How Years of Promise for Mental Health and Substance Use Disorders Came to Fruition with the Affordable Care Act

With passage of the Patient Protection and Affordable Care Act (ACA), the behavioral health community has achieved entry into the mainstream of U.S. health care. Passage of the law was the culmination of a long effort by advocates. At the same time, findings from research and practice have informed the nation's understanding that behavioral health is integral to health. The primary task before the behavioral health community now is to ensure that the advances of recent years are secured through implementation of the ACA and approaches to service delivery that emphasize integrated care.
Reusing Software: Issues and Research Directions

Software productivity has been steadily increasing over the past 30 years, but not enough to close the gap between the demands placed on the software industry and what the state of the practice can deliver; nothing short of an order of magnitude increase in productivity will extricate the software industry from its perennial crisis. Several decades of intensive research in software engineering and artificial intelligence left few alternatives but software reuse as the (only) realistic approach to bring about the gains of productivity and quality that the software industry needs. In this paper, we discuss the implications of reuse on the production, with an emphasis on the technical challenges. Software reuse involves building software that is reusable by design and building with reusable software. Software reuse includes reusing both the products of previous software projects and the processes deployed to produce them, leading to a wide spectrum of reuse approaches, from the building blocks (reusing products) approach, on one hand, to the generative or reusable processor (reusing processes), on the other. We discuss the implication of such approaches on the organization, control, and method of software development and discuss proposed models for their economic analysis. Software reuse benefits from methodologies and tools to: (1) build more readily reusable software and (2) locate, evaluate, and tailor reusable software, the last being critical for the building blocks approach. Both sets of issues are discussed in this paper, with a focus on application generators and OO development for the first and a thorough discussion of retrieval techniques for software components, component composition (or bottom-up design), and transformational systems for the second. We conclude by highlighting areas that, in our opinion, are worthy of further investigation. >
Control And Provisioning of Wireless Access Points (CAPWAP) Protocol Specification

This specification defines the Control And Provisioning of Wireless Access Points (CAPWAP) Protocol, meeting the objectives defined by the CAPWAP Working Group in RFC 4564. The CAPWAP protocol is designed to be flexible, allowing it to be used for a variety of wireless technologies. This document describes the base CAPWAP protocol, while separate binding extensions will enable its use with additional wireless technologies. [STANDARDS-TRACK]
Maternal Antibody Improves Active Neonatal Vaccination against RespiratorySyncytial Virus through Immune Complex

Respiratory syncytial virus (RSV) is a common infectious pathogen in infants. Vaccination is an important approach in the prevention of RSV infection in early age, but early vaccination is limited by low systemic and cellular immune responses. To overcome this difficulty, we in this study explored a novel vaccination strategy in a mouse model. Pregnant mother was vaccinated at day 14 of gestation and offspring were actively vaccinated at day 3 after birth. We observed a high level of maternal anti-RSV antibody in offspring born to the RSV immunized mother, but it declined 6 weeks after birth. However, anti-RSV antibody was low in offspring received active immunization alone. After offspring were nasal challenged with 2.8 × 105 i.u. RSV at age of 6 weeks old, we observed significant low levels of lung RSV load and inflammation in offspring received both passive and active vaccination as compared to the offspring received passive or active vaccination alone. The increased protection was associated with the increased endogenous production of anti-RSV antibody and Th1-biased cytokine IFN-gamma. Further in vitro study confirmed that maternal anti-RSV antibody and RSV antigen formed immune complex. The splenocytes stimulated with RSV immune complex expressed higher expression of IFN-gamma than those stimulated with RSV alone. Thus, maternal anti-RSV antibody increased efficacy of active vaccination in neonates as early as 3 days after birth and provided more protection against RSV than passive or active vaccination alone. Formation of RSV immune complex in respiratory mucusal tissues may contribute to the improved Th1-biased immune responses.
Anomalous exponents to order epsilon 3 in the rapid-change model of passive scalar advection.

Field-theoretic renormalization group is applied to the Kraichnan model of a passive scalar advected by the Gaussian velocity field with the covariance -~delta(t-t('))|x-x(')|(epsilon). Inertial-range anomalous exponents, related to the scaling dimensions of tensor composite operators built of the scalar gradients, are calculated to the order epsilon(3) of the epsilon expansion. The nature and the convergence of the epsilon expansion in the models of turbulence are briefly discussed.
Nuclear expression of maspin is associated with a lower recurrence rate and a longer disease‐free interval after surgery for squamous cell carcinoma of the larynx

Aims : Maspin, a protein belonging to the serpin superfamily, is the product of a tumour suppressor gene. Tissue distribution studies have shown maspin expression in normal mammary epithelial cells, in the placenta, prostate, thymus, testis, oral cavity, small intestine, skin, and cornea. Maspin is expressed but down‐regulated in human breast, prostatic, and colonic cancers but apparently up‐regulated in pancreatic, ovarian, and gastric cancers. Only two studies concerning maspin expression in head and neck carcinomas are available. The present study is the first attempt to determine maspin expression in laryngeal carcinoma.
Cine MR imaging in mitral regurgitation: comparison with color Doppler flow imaging.

Cine MR imaging is a new technique that combines short repetition times, limited flip angles, gradient-refocused echoes, and cardiac gating. This procedure was performed in 20 patients in whom mitral regurgitation was shown on left ventriculography, and the results were compared with those of color Doppler flow mapping. In all cases, mitral regurgitation on cine MR imaging was depicted as an area of decreased signal intensity within the left atrium. The extent and severity of the regurgitant jet as seen by the two techniques were classified visually as 4+ (severe), 3+ (moderate), 2+ (mild), and 1+ (minimal). The results of the two methods were the same in 14 (70%) of the 20 patients. In five patients the results differed by one grade and in one patient by two grades. In addition, the maximal intrusion distance and area of the regurgitant jet divided by the area of the left atrium as determined by the two methods were compared. The correlation coefficients between the two methods in regard to the length and area of mitral regurgitation were . 74 and . 71, respectively. These data suggest that the accuracy of cine MR imaging in assessing the severity of mitral regurgitation is comparable to that of color Doppler flow imaging.
Paradoxes between genetics and development.

The principles of genetic inheritance are based on clonal succession. In a simple eukaryotic haploid-diploid life cycle, for example that of yeasts and fungi, the products of meiosis are single haploid cells, which grow to form clones of genetically identical cells, leaving aside occasional mutations. Haploid cells fuse to form diploids, which may immediately divide by meiosis to produce four haploid clones, or may divide as a diploid clone before undergoing meiosis. In higher eukaryotes, there is also alternation of diploid and haploid cells, but haploidy is usually confined to the products of meiosis, the gametes, which fuse to restore diploidy in the zygote. Clonal expansion of the zygote implies that a population of identical cells is produced, and this may be true for the early embryo but, as everyone knows, it is no longer true as development proceeds. The organism with all its cell diversity is nevertheless a clone established by sequential mitotic division, during which the genome is faithfully copied. Although there may be exceptions, such as the formation of the immunoglobulin genes (Tonegawa, 1983), the genome remains essentially identical in all cells. This has been demonstrated by using DNA probes for a wide variety of genes: a positive signal can be obtained from any cell type or distinct tissue, and the DNA fragment sizes are constant (assuming that methyl-insensitive restriction enzymes are used). This provides modern confirmation of the classical nuclear transplantation experiments by Gurdon and collaborators in Xenopus, which showed that somatic nuclei are totipotent. Thus we have the paradoxical situation of the coexistence of accurate mitotic division with mechanisms that produce a variety of cells with specialized phenotypes in the adult organism.
Matrix Metalloproteinase-13 (MMP-13, Collagenase-3) is Highly Expressed in Human Tooth Pulp

Matrix metalloproteinases (MMPs) and their specific tissue inhibitors (TIMPs) participate into extracellular matrix degradation in physiological and pathological conditions. We hypothesized that MMP expression in pulp tissue changes in response to caries attack and investigated the gene expression profiles of MMPs and TIMPs in pulp tissue of sound and carious teeth with cDNA microarray. cDNA microarray demonstrated an extremely high MMP-13 (collagenase-3) mRNA expression in pooled pulp samples of sound and carious teeth, with less pronounced expression of MMP-16 (MT3-MMP) and TIMP-1. Real-time quantitative polymerase chain reaction of individual pulp samples revealed a wide range of the MMP-13 expression level between pulp samples with possible downregulation of MMP-13 expression during caries progression. Western blot and immunohistochemical staining confirmed the presence of MMP-13 with no observable differences between sound and carious teeth pulp tissues. The results reveal that MMP-13 is expressed and synthesized in pulp tissue, an interesting feature considering the very limited expression of MMP-13 in normal adult tissues. Further studies with a larger sample size are needed to clarify the changes in MMP-13 expression during caries progression.
Aortic diameter, aortic stiffness, and wave reflection increase with age and isolated systolic hypertension.

The October 2004 High Blood Pressure Research Council meeting of the American Heart Association included a debate on the proposition that “aortic diameter, aortic stiffness, and wave reflection all increase with age and in isolated systolic hypertension. ” This was stimulated by a series of articles1–5 that took a contrary position to change in aortic diameter and wave reflection and placed emphasis on aortic stiffness over wave reflection with aging and isolated systolic hypertension. The purpose of this review is to summarize the conventional view that has evolved over decades6–12 but is not precisely argued in recent literature. According to this view, early wave reflection from peripheral arteries is the dominant ill effect of aging and the most logical target for therapy.12–14 “Premature arterial senility” as a cardiovascular risk factor has long been of intense interest in actuarial studies, even before introduction of the cuff sphygmomanometer,6 as it had been in clinical medicine. The latter is apparent in the textbooks of Osler and Mackenzie >100 years ago.7,8 In these, premature arteriosclerotic change was assessed from the pulse waveform palpated at the wrist or measured from the radial artery by sphygmography. The first graphic recording studies of the arterial pulse by Marey in 18639 noted characteristic differences between young and old persons (Figure 1), with prominent late systolic augmentation (“tidal wave”) in the latter. Mahomed10,11 confirmed these changes in the 1870s, stressing that “the tidal wave is prolonged and too much sustained,” and noting similar pulse waveform changes in asymptomatic persons with elevated arterial pressure as well as in the elderly. By 1900, these findings were used by life insurance companies to decline applicants on the basis of premature arterial senility.6 Figure 1. Tracings from Marey’s original publication on the sphygmogram.9 Top, The …
Benign cranial dural arteriovenous fistulas: outcome of conservative management based on the natural history of the lesion.

OBJECT Cranial dural arteriovenous fistulas (DAVFs) can be classified into benign or aggressive, based on their patterns of venous drainage. A benign condition requires the absence of cortical venous drainage (CVD). The clinical and angiographic features of a consecutive single-center group of 117 patients harboring benign cranial DAVFs were evaluated over time to validate the behavior and appropriate management of these lesions. METHODS At the initial assessment four patients were asymptomatic. Two infants presented with congestive heart failure. All other patients presented with other benign symptoms: chronic headache, bruit, or orbital phenomena. Observational management was instituted in 73 patients (62%). Intolerable bruit or ophthalmological sequelae were deemed indications for palliative embolization in 43 patients and surgical treatment in one patient. A median follow-up period of 27.9 months (range 1 month-17.5 years) was available in 112 patients (95.7%), among whom repeated angiography was performed in 50. Overall, observational and palliative management resulted in a benign and tolerable level of disease in 110 (98.2%) of 112 cases. In two cases managed conservatively CVD developed. In both of these cases the conversion from benign to aggressive DAVF was associated with spontaneous progressive thrombosis of venous outlets. CONCLUSIONS The disease course of a cranial DAVF without CVD is indeed benign, obviating the need for a cure of these lesions. Symptoms are well tolerated with either observation or palliative treatment. After a long-term follow-up review of 68 patients, this conservative management resulted in a benign and tolerable level of disease in 98.5% of cases. It is noteworthy, however, that a benign DAVF carries a 2% risk of developing CVD, mandating close clinical follow-up review in such cases and renewed radiological evaluation in response to any deterioration in the patient's condition.
Should government intervene to protect nonprofits?

The emergence of investor-owned firms as major actors in U.S. health care financing and delivery has led to calls for federal and state intervention to protect nonprofits and to stem the for-profit sector's growth. High-profile scandals involving some of these firms have lent urgency to such proposals. This paper considers the case for government intervention to protect the nonprofit health sector. The controversy over the comparative merits of nonprofits and for-profits is reformed as a debate over the potential and limits of government action, and the case for a general presumption favoring protection for nonprofits is found to be unpersuasive.
Left ventricular systolic function assessment in patients with dilated heart failure using cardiovascular magnetic resonance

Cardiovascular magnetic resonance (CMR) has become a reference standard for the measure-ment of cardiac volumes, function, and mass. This study aims to reconstruct three dimen-sional modeling of the left ventricle (LV) in pa-tients with heart failure (HF) using CMRtools and thereby derive the LV functional indices. CMR images were acquired in 41 subjects (6 females) with heart failure (HF) and 12 normal controls (4 females). Five comparisons were made (i) nor-mal and dilated heart failure subjects, (ii) male and female normal heart, (iii) male and female dilated heart, (iv) male normal and dilated heart failure and (v) female normal and dilated heart failure. In HF, a significant higher values of EDV (320 刡 79 vs. 126 刡 22 ml, Paamp;lt;0.0001), ESV (255 刡 68 vs. 54 刡 12 ml, Paamp;lt;0.00001) and lower values of EF (20 刡 7 vs. 58 刡 5 %) were found compared that of normal control. There were significant difference on LV EDV and ESV between sex in both normal and HF subjects.
TMAP: Discovering relevant API methods through text mining of API documentation

Developers often migrate their applications to support various platform/programming‐language application programming interfaces (APIs) to retain existing users and to attract new users. To migrate an application written using 1 API (source) to another API (target), a developer must know how the methods in the source API map to the methods in the target API. Given that a typical platform or language exposes a large number of API methods, manually discovering API mappings is prohibitively resource‐intensive and may be error prone. The goal of this research is to support software developers in migrating an application from a source API to a target API by automatically discovering relevant method mappings across APIs using text mining on the natural language API method descriptions. This paper proposes text mining based approach (TMAP) to discover relevant API mappings. To evaluate our approach, we used TMAP to discover API mappings for 15 classes across (1) Java and C# API; and (2) Java ME and Android API. We compared the discovered mappings with state‐of‐the‐art source code analysis‐based approaches: Rosetta and StaMiner. Our results indicate that TMAP on average found relevant mappings for 56% and 57% more methods compared to the Rosetta and the StaMiner approaches, respectively.
William Jason Mixter (1880-1958). Ushering in the "dynasty of the disc".

William Jason Mixter was born in 1880 and graduated from the Harvard Medical School class of 1906. Like his father, Mixter was a prominent surgeon at the Massachusetts General Hospital, and in 1911 the two shared the job of overseeing all neurosurgery at that institution. By the early 1930s, W. J. Mixter was considered to be one of the nation's leading experts in spinal surgery, and he went on to become the first chief of the neurosurgery department at Massachusetts General Hospital. He served in the U. S. Army in both world wars and was actively involved in his local church community in Boston for many years. In 1934, at the age of 54, Mixter and Joseph S. Barr published an article on the intervertebral disc lesion in the New England Journal of Medicine. That article fundamentally changed the popular understanding of sciatica at that time, and for this work Mixter is generally credited by his contemporaries as being the man who best clarified the relation between the intervertebral disc and sciatica. Mixter and Barr's landmark report helped to establish surgery's prominent role in the management of sciatica at the time. Over the next few decades, discectomy surgery increased in popularity tremendously, and some refer to that period as the "dynasty of the disc. "
Autocorrelation function of the single PC polarization-mode dispersion emulator

The discrete structure of multisection polarization-mode dispersion (PMD) emulators is known to artificially correlate the PMD affecting different channels in a wavelength-division multiplexing system, thus limiting their usefulness in accurately emulating broad-band PMD. We report on the correlation properties of a novel single polarization controller (PC) PMD emulator, which offers scalability with the number of emulator sections through component reuse. We report a background level of the PMD frequency autocorrelation function of 0.66%, for a 50-section emulator, the lowest experimentally demonstrated for a PMD emulator, which makes the single PC PMD emulator an instrument of choice for research and development of broad-band PMD mitigation strategies.
2 . Bacteriophage research ; historical overview

Bacteriophages (phages) are naturally occurring viruses of bacteria that only infect and multiply within their specific bacterial hosts [1, 2]. Their host specificity is generally restricted at strain level, species level, or, more rarely, at the genus or class level. This specificity has allowed for directed targeting and killing of pathogenic bacteria using phages in what is referred to as phage therapy [2]. Phage therapy against infectious bacterial diseases was proposed and implemented shortly after the discovery of phages with partial success. However, the advent of antibiotics put an end to phage therapy research in many countries [3].
La gestión del conocimiento en pymes de servicios artesanales (I): el caso de las empresas de aplicación de pinturas.

El objetivo de este trabajo es disenar y aplicar un modelo de Gestion del Conocimiento para las pequenas y medianas empresas castellano-leonesas dedicadas a la aplicacion de pinturas, que les sirva para superar las dificultades que encuentran en el ambito de la innovacion en la gestion y la competitividad, frente a empresas de mayor tamano. Ademas, la seleccion y definicion de los componentes, procesos e hipotesis del modelo permiten que el mismo sea util y extrapolable a otras secciones del sector de servicios artesanales -ebanisteria, electricidad, fontaneria, etc.-.