Miracle-dz/UniFAR-FTUs huggingface dataset:
Antibodies of Mycobacterium in pleural effusion 1777 Detection of the antibody against LAM in the pleural effusion

ee front matter & 2006 med.2006. 01.023 ng author. Tel. : +81 172 ess: h03gm411@cc.hiro Summary Background: Diagnosing tuberculous pleural effusion (pTB) is often difficult because the culturing of tubercle bacilli results in a negative test in the majority of cases. Serological tests for the detection of antibodies to tuberculous glycolipid (TBGL) and lipoarabinomannan (LAM) have been introduced for the diagnosis of pulmonary tuberculosis. We examined the levels of these antibodies, adenosine deaminase (ADA) and interferon-g (IFN-g) in the pleural effusion and compared their diagnostic values in pTB. Methods: We studied 65 patients with pleural effusion. Of those, 19 patients were diagnosed as having pTB according to our broad case definition. The etiologies in the other 46 patients were malignant effusion, transdative effusion and miscellaneous diseases. Determiner TBGL antibody (D-TBGL-Ab) and MycoDot were used for the detection of anti-LAM and anti-TBGL antibodies, respectively, in the pleural effusion. Results: The sensitivity of ADA was 78.9% (15/19) and the specificity 97.8% (45/46). The sensitivity of IFN-g was 84.2% (16/19) and the specificity 93.5% (43/46). The sensitivities of D-TBGL-Ab and MycoDot were both 52.6% (10/19) and their specificities were 95.7% (44/46) and 97.8% (45/46), respectively. When DTBGL-Ab (cutoff point: 2.0 U/ml) and ADA activity (cutoff point: 57 IU/l) were combined, the sensitivity was 94.7% (18/19) and the specificity 93.5% (43/46). Conclusions: In the diagnosis of pTB, D-TBGL-Ab and MycoDot each have low sensitivity but high specificity. When D-TBGL-Ab is used in combination with ADA, the
Control system design optimisation via genetic programming

This paper describes a stochastic approach for comprehensive diagnostics and validation of control system architecture for unmanned aerial vehicle (UAV). Mathematically based diagnostics of a 6 DoF system provides capability for a complex evaluation of system components behaviour, but are typically both memory and computationally expensive. Design and optimisation of the flight controllers is a demanding task which usually requires deep engineering knowledge of intrinsic aircraft behaviour. Evolutionary algorithms (EAs) are known for their robustness for a wide range of optimising functions, when no a priori knowledge of the search space is available. Thus it makes evolutionary approach a promising technique to design the task controllers for complex dynamic systems such as an aircraft. In this study, EAs are used to design a controller for recovery (landing) of a small fixed-wing UAV on a frigate ship deck. The control laws are encoded in a way common for evolutionary programming. However, parameters (numeric coefficients in the control equations) are optimised independently using effective evaluation strategies, while structural changes occur at a slower rate. The fitness evaluation is made via test runs on a comprehensive 6 degree-of-freedom non-linear UAV model. The need of a well defined approach to the control system validation is dictated by the nature of UAV application, where the major source of mission success is based on autonomous control system architecture reliability. The results show that an effective controller can be designed with little knowledge of the aircraft dynamics using appropriate evolutionary techniques. An evolved controller is evaluated and a set of reliable algorithm parameters is validated.
Practical Flow Cytometry

The title of this book, Practical Flow Cytometry, may be somewhat misleading; a significant portion of the information presented is not essential to most investigators who utilize flow cytometry. The author's broad expertise in electronics, optics, histochemistry, and biology provides an excellent basis for discussion of the principles of flow cytometry and cell sorting; however, successful application of flow cytometry in many areas of research does not generally require such an in-depth knowledge of the technical details of the instrumentation. Many of the topics covered are of more importance to those directly involved with the operation and maintenance of flow cytometers, especially individuals who advise others with respect to the correct application of flow cytometry and cell sorting. Drawing on the author's background in theoretical as well as practical aspects of flow cytometry, important concepts are presented which will be useful to those in this field. Chapters include: the history of flow cytometry, how a flow cytometer works, analysis of flow cytometric data, flow sorting, measurable cellular parameters and fluorescence probes, descriptions of commercially available flow cytometers, and details for building your own flow cytometer. The theory of optical and electrical components is presented at a level requiring basic knowledge in those areas. Over 600 references which provide access to the literature of flow cytometry are cited; key references are recommended as "required reading" by the author. Also included are addresses and telephone numbers of commercial firms which supply dyes, antibodies, calibration particles, optical and electrical components, and the like. There is a definite need for a book with this information; the insight gained through the author's practical experience and his sense of humor (e.g., Shapiro's First Law of Flow Cytometry, "A 51 ,tm particle clogs a 50 ,um orifice") will be appreciated by those beginning in the field. The dot matrix type ("camera-ready copy using an Atari 800 computer") and illustrations drawn freehand are consistent with the author's economical writing style of relaying useful information without worrying about appearance.
A fast community detection algorithm

Community detection has been a hot area with the development of modern society. Many community detection algorithms have been proposed to detect communities in complex networks. But efficiency is still a great challenge for community detection algorithms. In this paper, we propose a fast community detection algorithm. Our algorithm first constructs initial communities according to the similarity between nodes. Secondly it arranges nodes and adjacent nodes which have smaller degrees to a community. Our algorithm has been proven by numerical experiments.
A 7-to-10b 0-to-4MS/s flexible SAR ADC with 6.5-to-16fJ/conversion-step

Applications like wireless sensor nodes require ultra-low-power ADCs. However, each application has different requirements for accuracy and bandwidth. Recent power-efficient ADCs for sensor applications are mostly designed for a fixed accuracy and a limited range of sample rates. An efficiently scalable sample rate (10kS/s to 10MS/s) has been demonstrated before, but without scalability of resolution. In, an ADC with both flexible resolution and sample rate is reported; however, its power efficiency is not as good as the point-solutions in. This paper describes a SAR ADC that achieves both good power efficiency (6.5-to-16fJ/conversion-step) and a wide range of flexibility (7-to-10b resolution, sample rates up to 4MS/s) to cover a large variety of applications, thereby reducing cost, design-time and overall complexity. To optimize the power efficiency for each resolution, both the DAC and comparator are reconfigurable. A 2-step conversion scheme is proposed for 9 and 10b settings to further reduce the power consumption. Finally, the use of an asynchronous architecture and dynamic circuitry ensures that the power consumption scales inherently proportional to the sample rate.
Report from the Second European Symposium on Clinical Laboratory and in vitro Diagnostic Industry. Physiological Reference Values: A Shared Business? Barcelona, 67 February 2003

A group of experts and interested professionals was asked a set of relevant questions on practical aspects of physiological reference value production and adoption. The discussions were structured in four parts, each related to a specific theme, followed by a final conclusion. The symposium began on Thursday, 6 February at 5:30 pm with a welcome by Xavier Fuentes-Arderiu followed by the first debate, and finished with a perfect dinner. The three other debates were distributed over the next day, ending with a common conclusion. Guests
AssesslDent of Guidance and Counseling Sel'vices in Govel'nlDent Technical and Vocational Education and Tl'aining Institutions in Addis Ababa

Vocational counseling is an interpersonal process designed to assist students/trainees with occupational development. Occupational development is that process of choosing, entering, adjusting to and advancing in an occupation. It is a lifelong process that interacts dynamically with other life roles. However, no adequate research and consideration has been done to improve the service. In this study an assessment was conducted in evaluating the quality of provisions of vocational guidance/counseling services in four government technical and Vocational Education and Training (TVET) institutions in Addis Ababa. A cross sectional survey was carried out using tools adopted from the 'guideline for vocational guidance and counseling services' by MOE The instruments were questionnaires, interviews, observational checklist and group discussions. A sample of 120 trainees, 11 vocational counselors, 80 teachers and 12 directors participated in the study. From the study, it was found that trainees were not assisted through the provision of pre-admition vocational guidance services. The provision of post-admition vocational guidance/counseling services were inefficient and non standardized. Vocational counselors were not prescribed with the relevant occupational information/training and did not take even a single course in vocational/career counseling. However, the majority of participants from each group believed the overall practices of guidance/counseling in the TVET institutions was high. The implications of the above results and other specific findings have been discussed in the body.
Invisible Hand: A Privacy Preserving Mobile Crowd Sensing Framework Based on Economic Models

Privacy issues are strongly impeding the development of mobile crowd sensing (MCS) applications. Under the current MCS framework, processes including bidding, task assignment, and sensed data uploading are all potentially risky for participants. As an effort toward this issue, we propose a framework that enhances the location privacy of MCS applications by reducing the bidding and assignment steps in the MCS cycle. Meanwhile, to reduce the unnecessary privacy loss while maintaining the required quality of service (QoS), economic theory is used to help both the service provider and participants to decide their strategies. We propose schemes based on both the Monopoly and Oligopoly models. In the former case, the participants cooperate to gain exclusive control of the supply of crowd sensing data, while the latter case is a state of limited competition. The parameters in different schemes are analyzed, and the strengths and weaknesses of both schemes are discussed. Additionally, the proposed schemes are evaluated by extensive simulations, and the results are discussed in detail.
Novel approach for cache memory simulation at approximately-timed TLM abstraction level for SMP system

To meet the ever increasing high speed computing requirements of complex System on Chips (SoC), there has been an increasing trend towards adopting Symmetric Multiprocessing (SMP) Systems encapsulating multiple processing cores each having multi-level cache memory for faster accesses. At an early design phase, estimating the requirement of - cache memory size and levels, prefetching strategy, snooping mechanism and coherency protocol to be adopted may save a lot of RTL simulation time and SoC area. Also, optimized cache parameters facilitate better SoC performance in terms of Bandwidth, latency, FIFO depth, arbitration policies etc. of various IP cores. In this work, keeping above in view, a novel approach is proposed to simulate coherent (Multi-Level) Cache Memory based on MESI protocol for Multi-Core Symmetric Multiprocessing (SMP) System deploying the benefits of Timed TLM simulations at an early design phase. The proposed Cache Memory system is provided with the memory reference traces extracted from earlier SoC simulation. Based on the user requirement, a memory hierarchy is dynamically generated which produces various cache memory access statistics which can be appropriately used for optimizing Cache Memory parameters.
Small nucleolar RNA‐guided post‐transcriptional modification of cellular RNAs

For a long time it was believed that the nucleotide sequence of every RNA would represent a simple copy of its coding DNA. This axiom of molecular biology, however, has suffered several jolts during the last 25 years. The discovery of intervening or intronic sequences (splicing) and the finding that individual nucleotides can be inserted into and deleted from RNAs (RNA editing) demonstrated that genetic information can be changed at the RNA level. Post‐transcriptional modification of individual ribonucleotides, namely deamination of adenosines and cytidines, can also change the readout of mRNAs (reviewed by Maas and Rich, 2000). Stable cellular RNAs, such as tRNAs, rRNAs and snRNAs, have long been known to contain a large number of post‐transcriptionally synthesized irregular ribonucleotides (Limbach et al ., 1994). In tRNAs, the modified nucleotides can facilitate the formation of correct anticodon–codon interaction and thereby increase the efficiency and fidelity of translation (reviewed by Agris, 1996). In rRNAs and spliceosomal snRNAs, methylation of the ribose moiety at the 2′‐hydroxyl group and conversion of uridines into pseudouridine are the most prevalent nucleotide modifications. Since 2′‐ O ‐methylated nucleotides and pseudouridines are restricted to the functionally essential regions of rRNAs and snRNAs (Reddy et al ., 1988; Maden, 1990), they are expected to contribute to the faithful function of the ribosome and the spliceosome. Consistent with this view, lack of ribosomal pseudouridines can reduce the growth rate or confer a selective disadvantage when it is competed against wild‐type ribosomes (Raychaudhuri et al ., 1999; Wrzesinski et al ., 2000). More tellingly, nucleotide modifications in the 5′‐terminal region of the U2 spliceosomal snRNA are absolutely essential for its function in pre‐mRNA splicing (Yu et al ., 1998). The human 18S, 5.8S and 28S rRNAs together carry ∼110 2′‐ O ‐methyl groups and almost 100 pseudouridines (Maden, 1990). Synthesis of this …
Fighting Iron Deficiency Anemia with Iron-Rich Rice

Objective: Iron deficiency is estimated to affect about 30% of the world population. Iron supplementation in the form of tablets and food fortification has not been successful in developing countries, and iron deficiency is still the most important deficiency related to malnutrition. Here we present experiments that aim to increase the iron content in rice endosperm and to improve its absorption in the human intestine by means of genetic engineering. Methods: We first introduced a ferritin gene from Phaseolus vulgaris into rice grains, increasing their iron content up to twofold. To increase iron bioavailability, we introduced a thermo-tolerant phytase from Aspergillus fumigatus into the rice endosperm. In addition, as cysteine peptides are considered major enhancers of iron absorption, we over-expressed the endogenous cysteine-rich metallothionein-like protein. Results: The content of cysteine residues increased about sevenfold and the phytase level in the grains about one hundred and thirtyfold, giving a phytase activity sufficient to completely degrade phytic acid in a simulated digestion experiment. Conclusions: This rice, with higher iron content, rich in phytase and cysteine-peptide has a great potential to substantially improve iron nutrition in those populations where iron deficiency is so widely spread.
Radial Velocities of 368 Helium Stars.

course, unknown. Probably it is small, but any such effect would bring the composition of the deeper parts of the Earth closer to that of olivine. The compressibility of a sample of tachylite (basaltic glass) was also measured and found to be 1.45 X 10-6 per megabar. The velocity of longitudinal waves in this material is calculated to be 6.45 km. /sec. , while the velocity in a holocrystalline rock of the same composition would be 6.9 km. /sec. 1 L. H. Adams and E. D. Williamson, "The Compressibility of Minerals and Rocks at High Pressures," J. Franklin Inst. , 195, 1923 (474-529). 2 Op. Cit.; see also L. H. Adams, E. D. Williamson and J. Johnston, J. Am. , Chem. Soc. , 41, 1919 (12-42). 3 Bridgman, P. W. , Proc. Am. A cad. Arts Sci., 58, 1923 (174). Washington, H. S. , "Petrology of the Hawaiian Islands. III. Kilauea and General Petrology," Am. J. Sci., 6, 1923 (351). 6 Bridgman, P. W. , Am. J. Sci., 10, 1925 (359-367). 6 Adams and Williamson, J. Franklin Inst. , 195, 1923 (524). 7 Op. cit., pp. 517, et seq. 8 For a discussion of the evidence in favor of a glassy, basaltic substratum, see R. A. Daly, Proc. Am. Philosoph. Soc. , 64, 1925 (283-307).
Impact of Inflation and GDP on CNX Nifty

: Inflation and GDP are the two main important macro-economic variables. GDP is an economic indicator of the market value of all finished goods and services produced over a period (Quarterly or yearly) of time. There has been a decline in the GDP growth rate in the year 2017 compared to previous year. Several factors including global situation are responsible for the decline in GDP growth rate. Inflation is a continual growth in the universal worth of goods and services in an economy over a period of time. When the price level increases, each component of currency buys fewer goods and services. This paper mainly deals with the impact of Inflation and GDP on Indian market that is National stock exchange (NSE). For this we have collected 10 years quarterly data and also applied E-views statistical package. Unit root test for stationary, co-integration test, vector error correction model, and granger causality test, were conducted.
Point-to-Point Iterative Learning Control With Optimal Tracking Time Allocation

Iterative learning control (ILC) is a high-performance tracking control design method for systems operating in a repetitive manner. This paper proposes a novel design methodology that extends the recently developed point-to-point ILC framework to allow automatic via-point time allocation within a given point-to-point tracking task, leading to significant performance improvements, e.g., energy reduction. The problem is formulated into an optimization framework with via-point temporal constraints and a reference tracking requirement, for which a two-stage design approach is developed. This yields an algorithmic solution, which minimizes input energy based on norm optimal ILC and gradient minimization. The algorithm is further expanded to incorporate system constraints into the design, prior to experimental validation on a gantry robot test platform to confirm its feasibility in practical applications.
Lipid content, mitochondrial activity and early embryo development in oocyte collected from crossbred cows (bos taurus indicus)

The objective of this research was to evaluate the effect of phenotypic predominance on lipid content, mitochondrial activity and early developmental competence as indicators of oocyte quality. Cumulus-oocyte complexes (COCs) were recovered through follicular aspiration, and underwent in vitro maturation (IVM), in vitro fertilization (IVF), and in vitro culture (IVC) of presumptive zygotes. Lipid content and mitochondrial activity in immature and IVM oocytes were determined. A maturation rate of 80.6% and 69.3% was found for oocytes predominantly B. indicus and predominantly B. taurus, respectively. Total fertilization rate was 27.6%; 26.1% for predominantly B. indicus oocytes and 29% for predominantly B. taurus oocytes. A total of 55.5% and 57.5% of cleaved embryos after 48 and 72 h post-insemination (hpi) in predominantly B. indicus group were observed, respectively. As for the predominantly B. taurus group, 48.6% and 60.4% of cleaved embryos were found after 48 and 72 hpi, respectively. In both groups, immature oocytes showed a greater amount of small lipidic droplets (p <0.0001); IVM decreased the number of small lipid droplets (p < 0.0001) and increased the number of medium and large lipid droplets (p < 0.0001). Predominantly B. indicus oocytes had a greater number of small and medium-sized lipid droplets, while there were no significant differences in large lipid droplets. IVM oocytes had higher mitochondrial activity than immature oocytes group (p < 0.05) without any effect of phenotypic predominance on this parameter. Assessment of lipid content was not a predictive factor of oocyte quality in crossbred cows.
A New Approach on the Canonical k-vertex Polygon Retrieval Problem on the Plane

The polygon retrieval problem on points is the problem of preprocessing a set of $n$ points on the plane, so that given a polygon query, the subset of points lying inside it can be reported efficiently. It is of great interest in areas such as Computer Graphics, CAD applications, Spatial Databases and GIS developing tasks. In this paper we study the problem of canonical $k$-vertex polygon queries on the plane. A canonical $k$-vertex polygon query always meets the following specific property: a point retrieval query can be transformed into a linear number (with respect to the number of vertices) of point retrievals for orthogonal objects such as rectangles and triangles (throughout this work we call a triangle orthogonal iff two of its edges are axis-parallel). We present two new algorithms for this problem. The first one requires $O(n\log^2{n})$ space and $O(k\frac{log^3n}{loglogn}+A)$ query time. A simple modification scheme on first algorithm lead us to a second solution, which consumes $O(n^2)$ space and $O(k \frac{logn}{loglogn}+A)$ query time, where $A$ denotes the size of the answer and $k$ is the number of vertices. The best previous solution for the general polygon retrieval problem uses $O(n^2)$ space and answers a query in $O(k\log{n}+A)$ time, where $k$ is the number of vertices. It is also very complicated and difficult to be implemented in a standard imperative programming language such as C or C++.
Propagation of Beta / Gamma Rhythms bioRxiv Submission v 4 . 0 in the Parkinsonian Rat 24 / 08 / 2017 1 Propagation of Beta / Gamma Rhythms in the 1 Cortico-Basal Ganglia Circuits of the 2 Parkinsonian Rat 3

21 The functional impairment of the motor system associated with Parkinson’s Disease is thought to arise 22 as a result of pathological synchronization of the networks formed by the basal ganglia and motor 23 cortex. In this paper, we investigate changes to the directed connectivity in these networks following 24 chronic dopamine depletion to evaluate the plausibility of a number of hypotheses proposed to explain 25 . CC-BY-NC-ND 4.0 International license not peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was . http://dx.doi. org/10.1101/180455 doi: bioRxiv preprint first posted online Aug. 24, 2017;