Miracle-dz/UniFAR-FTUs huggingface dataset:
Fuling Sini decoction for patients with chronic heart failure

Background: Chronic heart failure (CHF) is one of the most important cardiovascular diseases worldly, with high morbidity and mortality. Fuling Sini decoction (FSD) has been used in the management of CHF widely in China, while its effective evidence is not clear. A systematic review and meta-analysis to evaluate FSD for CHF is lacking. Hence, we propose a protocol for systematic evaluation of its efficacy and safety for CHF. Methods: We will search the following electronic databases from inception to October 2018, including EMBASE, Cochrane Center Registration Controlled trials (Cochrane Library), PubMed, Medline, WHO International Clinical Trials Registry Platform, China Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), and Wan-fang database. Only randomized controlled trials (RCTs) of FSD alone or combined with other management for CHF will be included. Two independent reviewers will screen the literature and extract data according to the Cochrane Handbook method. The assessment of bias risk, data synthesis, subgroup analysis, and meta-analyses and finally meta-analysis will be performed by using RevMan V.5. 3.5 software. Results: This systematic review will provide high-quality evidence and may be the first to evaluate efficacy and safety of FSD in the treatment of CHF. Conclusion: This systematic review will provide evidence for judging whether FSD is an effective management for CHF or not. PROSPERO registration number: CRD 42018110210.
Further Evidence of the Zero-Association Between Symptoms of Insomnia and Facial Emotion Recognition—Results From a Sample of Adults in Their Late 30s

Background: Restoring sleep is associated with favorable cognitive, emotional, and behavioral adaptations. As regards the association between sleep duration and facial emotion recognition (FER), results are conflicting, and as regards the association between symptoms of insomnia and FER, no study has been performed so far. Accordingly, the aim of the present study was to investigate whether subjective sleep was associated with FER, along with perceived stress and mental toughness. Method: A total of 201 police officers (mean age = 38.5 years, 64.2% males) took part in the present cross-sectional study. They completed questionnaires covering socio-demographic data, subjective symptoms of insomnia, perceived stress, and mental toughness. Further, they underwent a computerized FER test, consisting of facial emotion labeling and facial emotion matching. Results: Performance of FER (accuracy, speed) was unrelated to subjective symptoms of insomnia. Lower FER was associated with higher age, but not to perceived stress or mental toughness. No gender differences were observed. Higher symptoms of insomnia were associated with higher stress scores and lower scores of mental toughness. Conclusions: The pattern of results suggests that FER was not associated with symptoms of insomnia, understood as a proxy of sleep quality, among adults. This observation replicates those studies showing a zero-association between sleep and FER.
Bioelectrochemical Stimulation of Electromethanogenesis at a Seawater-Based Subsurface Aquifer in a Natural Gas Field

In subsurface anoxic environments, microbial communities generally produce methane as an end-product to consume organic compounds. This metabolic function is a source of biogenic methane in coastal natural gas aquifers, submarine mud volcanoes and methane hydrates. Within the methanogenic communities, hydrogenotrophic methanogens and syntrophic bacteria are converting volatile fatty acids to methane syntrophically via interspecies hydrogen transfer. Recently, direct interspecies electron transfer (DIET) between fermentative/syntrophic bacteria and electrotrophic methanogens has been proposed as an effective interspecies metabolite transfer process to enhance methane production. In this study, in order to stimulate the DIET-associated methanogenic process at deep biosphere-aquifer systems in a natural gas field, we operated a bioelectrochemical system (BES) to apply voltage between an anode and a cathode. Two single-chamber BESs were filled with seawater-based formation water collected from an onshore natural gas well, repeatedly amended with acetate, and operated with 600 mV between electrodes for 21 months, resulting in a successful conversion of acetate to methane via electrical current consumption. One reactor yielded a stable current by ~200 mA/m2 with a coulombic efficiency (CE) of >90%; however, the other reactor, which had been incidentally disconnected for 3 days, showed less electromethanogenic activity with a CE of only ~10%. The 16S rRNA gene-based community analyses showed that two methanogenic archaeal families, Methanocalculaceae and Methanobacteriaceae, were abundant in cathode biofilms that were mainly covered by single-cell-layered biofilm, implicating them as key players in the electromethanogenesis. In contrast, family Methanosaetaceae was abundant at both electrodes and the electrolyte suspension only in the reactor with less electromethanogenesis, suggesting this family was not involved in electromethanogenesis and only activated after the no electron flow event. On anodes covered by thick biofilms with filamentous networks, family Desulfuromonadaceae dominated in the early stage of the operation, while family Geobacteraceae (mainly genus Geoalkalibacter) increased their frequencies during the longer-term operation, which indicates that these families were correlated with electrode-respiring reactions. These results indicate that the BES reactors with voltage application effectively activated a subsurface DIET-related methanogenic microbiome in the natural gas field, and specific electrogenic bacteria and electromethanogenic archaea were identified within the anode and/or cathode biofilms.
The Neuroprotector Benzothiazepine CGP37157 Extends Lifespan in C. elegans Worms

The benzothiazepine CGP37157 has shown neuroprotective effects in several in vitro models of excitotoxicity involving dysregulation of intracellular Ca2+ homeostasis. Although its mechanism of neuroprotection is unclear, it is probably related with some of its effects on Ca2+ homeostasis. CGP37157 is a well-known inhibitor of the mitochondrial Na+/Ca2+ exchanger (mNCX). However, it is not very specific and also blocks several other Ca2+ channels and transporters, including voltage-gated Ca2+ channels, plasma membrane Na+/Ca2+ exchanger and the Ca2+ homeostasis modulator 1 channel (CALHM1). In the present work, we have studied if CGP37157 could also induce changes in life expectancy. We now report that CGP37157 extends C. elegans lifespan by 10%–15% with a bell-shaped concentration-response, with high concentrations producing no effect. The effect was even larger (25% increase in life expectancy) in worms fed with heat-inactivated bacteria. The worm CGP37157 concentration producing maximum effect was measured by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) and was close to the IC50 for inhibition of the Na+/Ca2+ exchanger. CGP37157 also extended the lifespan in eat-2 mutants (a model for caloric restriction), suggesting that caloric restriction is not involved in the mechanism of lifespan extension. Actually, CGP37157 produced no effect in mutants of the TOR pathway (daf15/unc24) or the insulin/insulin-like growth factor-1 (IGF-1) pathway (daf-2), indicating that the effect involves these pathways. Moreover, CGP37157 was also ineffective in nuo-6 mutants, which have a defect in the mitochondrial respiratory chain complex I. Since it has been described that neuroprotection by this compound in cell cultures is abolished by mitochondrial inhibitors, this suggests that life extension in C. elegans and neuroprotection in cell cultures may share a similar mechanism involving mitochondria.
Selected Principles of Pankseppian Affective Neuroscience

In the early nineties of the twentieth century Jaak Panksepp coined the term “Affective Neuroscience” (AN) today being accepted as a unique research area in cross-species brain science. By means of (i) electrical stimulation, (ii) pharmacological challenges, and (iii) brain lesions of vertebrate brains (mostly mammalian), Panksepp carved out seven primary emotional systems called SEEKING, CARE, PLAY, and LUST on the positive side, whereas FEAR, SADNESS, and ANGER belong to the negative affects. Abundant research into human clinical applications has supported the hypothesis that imbalances in these ancient primary emotional systems are strongly linked to psychiatric disorders such as depression. The present paper gives a concise overview of Panksepp's main ideas. It gives an historical overview of the development of Panksepp's AN thinking. It touches not only areas of neuroscience, but also shows how AN has been applied to other research fields such as personality psychology. Finally, the present work gives a brief overview of the main ideas of AN.
Therapeutic Options Targeting Oxidative Stress, Mitochondrial Dysfunction and Inflammation to Hinder the Progression of Vascular Complications of Diabetes

Type 2 diabetes mellitus is a leading cause of morbidity and mortality worldwide, given its serious associated complications. Despite constant efforts and intensive research, an effective, ubiquitous treatment still eludes the scientific community. As such, the identification of novel avenues of research is key to the potential discovery of this evasive “silver bullet. ” We focus on this review on the matter of diabetic injury to endothelial tissue and some of the pivotal underlying mechanisms, including hyperglycemia and hyperlipidemia evoked oxidative stress and inflammation. In this sense, we revisited the most promising therapeutic interventions (both non-pharmacological and antidiabetic drugs) targeting oxidative stress and inflammation to hinder progression of vascular complications of diabetes. This review article gives particular attention to the relevance of mitochondrial function, an often ignored and understudied organelle in the vascular endothelium. We highlight the importance of mitochondrial function and number homeostasis in diabetic conditions and discuss the work conducted to address the aforementioned issue by the use of various therapeutic strategies. We explore here the functional, biochemical and bioenergetic alterations provoked by hyperglycemia in the endothelium, from elevated oxidative stress to inflammation and cell death, as well as loss of tissue function. Furthermore, we synthetize the literature regarding the current and promising approaches into dealing with these alterations. We discuss how known agents and therapeutic behaviors (as, for example, metformin, dietary restriction or antioxidants) can restore normality to mitochondrial and endothelial function, preserving the tissue’s function and averting the aforementioned complications.
Detection and Genotyping Study of Enterocytozoon bieneusi in Sheep and Goats in East-central China

Enterocytozoon bieneusi, the dominant zoonotic species of microsporidia, has been reported in various animals and humans. However, relatively little information is available concerning the worldwide prevalence and genotypes of E. bieneusi in ruminants, such as sheep and goats. The present study was conducted to evaluate the prevalence and genetic characteristics of E. bieneusi in sheep and goats in east-central China. Fresh fecal samples from 832 sheep and 781 goats were evaluated for the presence of E. bieneusi using PCR and sequencing of the ribosomal internal transcribed spacer. 28 sheep specimens (3.4%) and 32 goat specimens (4.1%) were positive for E. bieneusi. A total of 12 ITS genotypes were identified, including 7 known genotypes (COS-I, OEB1, BEB6, CHG1, CHG3, COS-II, and CHC8) and 5 novel genotypes (named AHS1, AHS2, JSS1, AHG1, and AHG2). The dominant genotypes in sheep and goats were BEB6 and CHG3, respectively. Phylogenetic analysis revealed that all genotypes obtained in this study belonged to the so-called “cattle-specific” Group 2. These findings show a relatively low occurrence and genetic diversity of E. bieneusi in sheep and goats in east-central China. Further studies are required to elucidate the role of sheep and goats in the epidemiology of microsporidia.
Radiation Pattern Reconfigurable Antenna for MIMO Systems with Antenna Tuning Switches

A radiation pattern reconfigurable antenna for MIMO applications in mobile communication systems is proposed. The proposed design is a monopole antenna with two reflective strips and two antenna tuning switches. By controlling the antenna tuning switches between the strips and the ground plane, two switchable radiation patterns with correlation coefficient as low as 0.15 are achieved.
Enabling Accurate Modeling of Wave Propagation in Complex Tunnel Environments with the Vector Parabolic Equation Method

Vector parabolic equation (VPE) methods can be employed as channel models for large-scale tunnel propagation problems with high accuracy and computational efficiency. As with most site-specific models, a geometrical description of the modeling environment is required. However, the relevant literature is rather limited in terms of how to apply VPE to complex, realistic environments and what level of detail is necessary and sufficient to obtain results agreeing with measurements. In this paper, we present a thorough framework on enabling accurate modeling of wave propagation in complex tunnel geometries via VPE. The performance is validated against measured data in London Underground subway tunnels.
Synthesis of Steerable Maximally Sparse Array Via Modified Perturbed Compressive Sampling

In this paper, a new method based on the modified perturbed compressive sampling for the synthesis of steerable maximally sparse arrays is proposed. By considering the impact of invisible space region in the synthesis progress, the deterioration of the sidelobe level (SLL) during the scanning of the sparse array is addressed. Simulation example demonstrate the improvement of the SLL performance. Then, the relations among the array sparsity, array aperture and scanning region are analyzed and discussed through a series of simulation examples. The curves describing the relations are given.
Bandwidth Enhancement by Position Perturbations in Stacked Dielectric Resonator Antenna

In this paper, the effect of position perturbations on the bandwidth of an aperture coupled dielectric resonator antenna (DRA), is presented. Two combinations of stacked DRA's are considered for the analysis: larger over smaller (LOS), and smaller over larger (SOL). Different position perturbations on transmission line (TL), LOS, and SOL are applied to widen the matching bandwidth of the antenna. The performance of the proposed antenna are compared with the conventional antenna designed with no perturbations. The proposed antenna not only provides 5:1 ultra-wide matching bandwidth (from 2.7 GHz to 13.6 GHz), but also result in a highest gain of 9 dBi, which is 2 dBi more than the antenna designed with conventional method with no perturbation.
A Dual-Band Quadrature Hybrid Coupler Using Embedded MTM-EBGs

A novel dual-band quadrature hybrid coupler is presented, the branches of which are loaded with MTM-EBG unit cells to enable dual-band performance. The coupler utilizes the MTM-EBG's microstrip-like-mode bandgap to present 90° phase shifts at two frequencies, which can be nearly independently chosen and designed. The coupler is fabricated, and experimental results show good agreement with the simulated response.
Study on the Difference of Reaching Cognition Between the Real and the Virtual Environment Using HMD and its Compensation

The purposes of this research are to investigate the information necessary for cognition of the VR environment using “Reaching” and to examine how to compensate the difference of cognition between the real and the VR environment. Therefore, this research conducts a task in VR to acquire cognition with the VR environment (Cognitive acquisition task) first. This task is one for a subject to be acclimated to VR environment. The important thing is that the subject’s arms and hands and their actions are shown in VR environment using CG. Second, comparative experiment using Reaching is conducted. Cognitive acquisition task is conducted using simple action task related to reaching, such as stacking blocks and rolling spheres. In Reaching experiment, first, a subject estimate whether the subject can grasp a cylinder placed in front of the subject by just stretching arms in thought. After that, the subject grabs the cylinder and places it as far as possible. The results are investigated in the real and the virtual environment. In the real, it has been found that the longest distance to an object for a person to decide to be able to reach for and grab the object (CDDG) is about 1.1 times as long as the longest distance where a person actually can reach for grabbing the object (CRDG). The previous studies have shown that the ratio of CDDG and CRDG in VR is not 1.1 and its compensation is difficult. However, as a result of this research experiment, CDDGs in this research were the same value in the real and the VR environment. And in the case of VR with reduced environmental information, CDDG in VR was different from one in real. As the result, it was suggested that the difference in cognition could be compensated by including the necessary and sufficient environmental and user’s information (CG model of user’s body and user’s movement) and an appropriate cognition could be realized even in the current VR environment.
A Ultra-Wideband Monocone Antenna with Ceramic Loading

A low-profile top-hat shorted monocone antenna with ceramic loading is proposed. SiO2, a kind of ceramic, is first employed as matching layer to improve antenna's matching property and support the antenna's structure. Besides, for further increasing the bandwidth of monocone antenna, top hat and shorting pins are applied to reduce the lowest operating frequency and thus decrease the thickness of the monocone antenna to O. 068λLow. Simulated results show that a 6:1 bandwidth can be obtained.
Effect of Antenna Element Placement on Chassis Modes

In this paper, the effect of an actual antenna element location on the chassis modes is investigated. The chassis modes are significantly affected by the presence of the antenna and the amount of effect depends on the structure as well as the location of the antenna on the chassis. The presence of the antenna also creates a new mode that only depends on the geometry of the antenna and is not affected by the location of the antenna on the chassis. In the presence of the antenna, the current maxima of all the modes shift towards the antenna element, that is why pure excitation of single characteristic mode is not possible.
Low-Cost Wide-Band V-Band Patch Antenna on FR4 PCB

Cost-effective and easy-to-manufacture antennas are key factors for 5G wireless high data rate links. In this context, we present a patch antenna designed on FR4-PCB for WiGig and backhaul applications, operating in the 60 GHz unlicensed spectrum. Yielding 20% measured 10 dB impedance-bandwidth and a maximum measured gain of 6 dBi, it stands out as a very competitive antenna compared to V -band FR4 PCB antennas found in literature. Furthermore, this antenna is suitable for illuminating a high gain dielectric lens for mobile backhaul.
A Cross-Domain SDN Architecture for Multi-Layered Space-Terrestrial Integrated Networks

The MLSTIN is considered as a powerful architecture to meet the heavy consumer demand for wireless data access in the coming 5G ecosystem. However, due to the inherent heterogeneity of MLSTIN, it is challenging to manage the diverse physical devices for large amounts of traffic delivery with optimal network performance. As promoted by the advantage of SDN, MLSTIN is expected to be a flexible paradigm to dynamically provision various applications and services. In light of this, a cross-domain SDN architecture that divides the MLSTIN into satellite, aerial, and terrestrial domains is proposed in this article. We discuss the design and implementation details of this architecture and then point out some challenges and open issues. Moreover, illustrative results validate that the proposed architecture can significantly improve the efficiencies of configuration updating and decision making in MLSTIN.
The Suppression of Quadrant Glitches with Ball-Screw-Driven Stage

Friction undermines the accuracy of position control in high-precision milling machines, where quadrant glitches occurs as one cutting axis reverses. In order to figure out the detailed cause of the quadrant glitches, this paper first obtained speed and position response through simulation of one-inertia servo system. Then we adopted friction feedforward method to compensate the effect of friction. The feedforward compensation is based on Coulomb friction model, Coulomb + viscous friction model and LuGre friction model. Both simulation and experimental result shows the validness the proposed method.
Analysis of Electromagnetic Interference in Electric Vehicle Cables

The development of electric cars that use large electrical voltages, release harmonics that cause interference in nearby systems. This study carried out simulations with the CST software, which simulated the induction of a pulse in cables of electric vehicles that can cause interference in other equipment or systems that operate in frequency bands of 200 MHz to 800 MHz.
Tx/Rx Antenna System for Full-Duplex Application

This paper presents the design of an antenna system consisting of a Tx and a Rx antenna close to each other for SISO, MISO or SIMOFull Duplex applications. The reduction of the self-interference or mutual coupling is obtained by combining a compact two patches array and a single patch placed to specific chosen positions determined thanks to parametric studies in order to obtain a diversity system. Thus, an isolation level better than 50 dB at 5.5 GHz is reached. A good agreement between measured and simulated results is also observed. This result, combined with analog and digital cancellation techniques, can satisfy the self-interference challenge of Full Duplex system.