Miracle-dz/UniFAR-FTUs huggingface dataset:
Sensory Neuropeptides in Human Cranial Arteries. Mode of Action

Human cranial arteries (cerebral, middle meningeal and temporal) have been shown to be innervated with sensory fibres having their origin in the trigeminal ganglia and in the dorsal root ganglia at the C2 level. Peptides shown to be present in these nerves are tachykinins (substance P (SP), neurokinin A (NKA), neuropeptide K (NPK)) and calcitonin gene-related peptide (CGRP). Since the trigeminal ganglion has been shown to be activated in the course of migraine attacks we considered it worthwhile to examine the effects of the above putative neurotransmitters on various cranial vascular regions in order to understand a possible postjunctional effect in man during their release(1). For studying the vasomotor responses, circular segments (1-2 mm long) of the cranial arteries were removed during surgery. The specimens were mounted on two L-shaped metal prongs and the effects of the neuropeptides were tested using a sensitive in vitro technique. Some experiments were performed on arteries in which the endothelium had been removed beforehand mechanically by rubbing the intimal surface with a wooden stick. All peptides tested invariably resulted in concentration-dependent relaxations of precontracted arteries of different cranial regions. In cerebral arteries the order of potency was CGRP<SP<NKB<NKA=NPK (pD2: 9.9, 9.4, 8.2, 7.7 and 7.2 respectively), I , , , for all peptides was between 96 and 81% of the contraction elicited by PGFZa. In the midlde meningeal artery the order of potency was SP<CGRP<NKA (pD2: 9.9, 8.7 and 7.6, respectively) with I for CGRP 85% and for SP and NKA between 57 and 52ga;f the PGFZa induced contraction. In the temporal artery, SP was as potent as CGRP (pD2 8.7) both being more potent than NKA (pD2: 7.7). In the cranial arteries, the relaxant response to each of the &achykin'ns was blocked by the blocker spantide (1010 M). 4
Motivated Beliefs in Collective Decisions

Claiming that agents are rational during decision-making processes does not coincide with the fact that they keep making the same mistakes or keep on believing in some theory, even after it has been proven wrong. In order to incorporate social sciences’ insights into the standard economic models, this dissertation develops a theoretical framework that helps to understand how the desire for conformity with a group affects the opinions that each agent individually expresses and, consequently, the final decision of the group. In order to study the relationship between an individual and the group he is part of, I will analyse the existing literature on Motivated Beliefs and Groupthink as a basis for this work, explaining in detail their concepts, the mechanisms through which they act and the consequences they generate. Accordingly, I will develop a model based on existing knowledge about game theory, more precisely about sequential games, in order to study the optimal outcome of an agent in a decision-making process, considering that the agent has an interest in conforming with the group of which he is a member.
A multifactorial analysis of metaphors in political discourse

The rising prominence of women in politics has sparked a growing interest in comparing the language of male and female politicians. Many researchers have explored whether gender in politics has had an impact on their metaphor styles. While these studies have been oriented qualitatively and have concentrated on the two-way interaction between metaphor and gender, the possibility that metaphor and gender may interact with other additional factors is largely overlooked. This article adopts a quantitatively oriented approach complemented with textual analysis to explore potential multiple-way interactions between ‘metaphor’, ‘gender’, ‘speech section’ and ‘political role’ in political discourse. By conducting a case study of metaphor use in Hong Kong political speeches, we found evidence of gendered metaphors and their variability according to politicians’ political roles and different rhetorical sections in their speeches.
The Correlation of Exchange Rate and Inflation and Its Effect on Stock Markets. Case Study on Consumer Good Index Indonesia: 2004 – 2017

The purpose of this study is to see whether inflation and exchange rates have a two-way relationship and their influence on the stock market case study on the Consumer Good Index. In the first session the author wrote the introduction of the important of researching this topic, session two literature reviews about exchange rates, inflation and the stock market, the third session about the research methods and the fourth session described the overall discussion. The data used are monthly time series data from 2004 to 2017 and the estimation model used the VAR model. The exchange rate used Rupiah against U$D and inflation measure used Consumer Price Index. The results show that inflation do not affect the exchange rate, but the exchange rate significantly affect the inflation rate. As the stock market, there is a continuing decline or negative movement when inflation increased. Then when the Rupiah exchange rate continues to show a depreciating trend, the movement of the stock market seems to be decreasing.
Olympiads in Informatics as a Mechanism of Training World-Class Professionals in ICT

The development of information technologies has not brought only positive aspects to the society, but also negative ones: youth isolation, Internet addiction, inability to express thoughts logically, poor physical health, etc. Such problems impede the process of youth development and making professionals of them. But Olympiads in Informatics and Programming can turn the teens’ obsession with computers and the Internet into huge advantage that will be very beneficial in future. The research undertaken analysed the role of Olympiads in Informatics and Programming and proved that Olympiads are effective mechanisms of investments into youth. The research covered about 300 students of Computer Technology Chair of ITMO University (St. Petersburg National Research University of Information Technologies, Mechanics and Optics) and the latest data on the factors motivating students were received. In particular, that there is interconnection between Olympiads and students’ motivation in acquiring the profession; that Olympiads contribute to the effective development of youth; and that they provide opportunity to get a good education that will bring financial prosperity, career satisfaction and self-realization.
Phoenix Ink: Psychodynamic Motivations for Tattoo Attainment by Survivors of Trauma

Tattoos adorn people from all over the world and date back as far as the Stone Age. Tattoos adorn people from all over the world and motivations for tattoo attainment have been studied recently. Still, there remains limited research on the potential therapeutic properties of tattoo attainment, particularly for survivors of sexual trauma. The purpose of this study was to investigate the experience of the tattoo process for survivors of sexual trauma and their motivations for tattoo attainment. This qualitative exploratory study interviewed both survivors of sexual trauma (N=10) and tattoo artists (N=7) to gain a wider perspective on the motivations for tattoo attainment among survivors of sexual trauma. Common themes of tattoo attainment emerged among trauma survivors, with the most prevalent being reclamation, catharsis, and tattoo acts as personal narrative. Among tattoo artists the common themes were that tattoos act as non-normative expression and have therapeutic qualities. Further research should include diversified populations and a larger sample size. Implications for social work practice include utilizing tattoo for narrative exploration and rapport building.
Mechanisms of Two-Electron and Four-Electron Electrochemical Oxygen Reduction Reactions at Nitrogen-Doped Reduced Graphene Oxide

Doped carbon-based systems have been extensively studied over the past decade as active electrocatalysts for both the two-electron (2e-) and four-electron (4e-) oxygen reduction reaction (ORR). However, the mechanisms for ORR are generally poorly understood. Here we report an extensive experimental and first-principles theoretical study of the ORR at nitrogen-doped reduced graphene oxides (NrGO). We synthesize three distinct NrGO catalysts and investigate their chemical and structural properties in detail via X-ray photoelectron spectroscopy, infrared and Raman spectroscopy, high-resolution transmission electron microscopy and thin-film electrical conductivity. ORR experiments include the pH dependences of 2e- versus 4e- ORR selectivity, ORR onset potentials, Tafel slopes and H/D kinetic isotope effects. These experiments show very different ORR behavior for the three catalysts, both in terms of selectivity and the underlying mechanism which proceeds either via coupled proton-electron transfers (CPETs) or non-CPETs. Reasonable structural models developed from DFT rationalize this behavior. The key determinant between CPET vs. non-CPET mechanisms is the electron density at the Fermi level under operating ORR conditions. Regardless of the reaction mechanism or electrolyte pH, however, we identify the ORR active sites as sp2 carbons that are located next to oxide regions. This assignment highlights the importance of oxygen functional groups, while details of (modest) N-doping may still affect the overall catalytic activity, and likely also the selectivity, by modifying the general chemical environment around the active site.
Social media fandom for health promotion? Insights from East Los High, a transmedia edutainment initiative

As digital media technologies proliferate and social media spaces expand, how does one leverage popularity and cultivate fandom to promote health? Despite the easy entry, broad reach, and interactive features of social media such as Facebook and Twitter, health promoters are unsure how to meaningfully engage users and build lasting online communities. In this article, we examined the Facebook Insights and Twitter hashtag network over a nine-month period for Season 1 of the exemplary transmedia edutainment show East Los High. Premiered on Hulu, the popular entertainment streaming site, East Los High was purposefully designed to serve Latino youths in the United States, spurring conversations and promoting healthy relationships and safe sex practices across different digital platforms. We used Facebook analytics to gauge the audience reach, engagement, and dissemination; developed a 10-indicator index to identify the most successful among the 352 Facebook posts; analysed the position of East Los High in the Facebook co-commenting network; and assessed the top word pairs from those Facebook comments in accordance with the show’s social objectives. We also studied the underlying structure of the Twitter hashtag network representing the interactions between @EastLosHighShow and its 2,136 followers with tweets that included #ELH, #ELHaddict(s), and/or #EastLosHigh. While challenges exist in initiating and maintaining user engagement on these social media platforms, our findings revealed effective and actionable strategies for health promotion by cultivating fandom and building communities on social media.
Short- and Intermediate-term Results of : The Milan Dose-response Studyp Radioactive β-emitting Stent Implantation in Patients With Coronary Artery Disease: The Milan Dose-response Study

Radioactive 32P β-emitting stents have been shown to reduce intrastent neointimal hyperplasia in a substantial dose-related manner in the animal model. The aim of this dose-response study was to evaluate, in the clinical setting, the safety and efficacy at 6-month follow-up of this approach to reducing restenosis. A total of 122 32P radioactive β-emitting stents (initially the Palmaz-Schatz and later the BX Isostent) with an activity level of 0.75 to 3.0 μCi (group 1), 3.0 to 6.0 μCi (group 2), and 6.0 to 12.0 μCi (group 3) were implanted in 91 lesions in 82 patients. There were no procedural events. At 6-month follow-up, no deaths had occurred, and only 1 patient had stent thrombosis. Pure intrastent binary restenosis was 16% in group 1, 3% in group 2, and 0% in group 3. However, intralesion restenosis was 52% in group 1, 41% in group 2, and 50% in group 3. The use of 32P radioactive β-emitting stents in patients with CAD is feasible. At 6-month follow-up, intrastent neointimal hyperplasia was reduced in a dose-related manner. However, in the 3 groups, intralesion restenosis was high because of a high late lumen loss in the reference segments at the stent edges, possibly as a result of a low activity level of radiation at the edges of the stent combined with an aggressive approach to stenting. We called this “edge effect” the “candy wrapper. ”
Tutorial de desenvolvimento de métodos de programação linear inteira mista em python usando o pacote Python-MIP

O pacote Python-MIP oferece um conjunto abrangente de ferramentas para modelagem e resolucao de Problemas de Programacao Inteira Mista em Python. Alem de oferecer uma linguagem de modelagem de alto nivel, o pacote permite o desenvolvimento de metodos avancados, habilitando a comunicacao bidirecional com o pacote de otimizacao durante o processo de busca. Neste tutorial, desenvolveremos metodos de Programacao Linear Inteira Mista para o Problema do Caixeiro Viajante. Iniciando com um metodo simples baseado em uma formulacao compacta iremos evoluir para um metodo que combina heuristicas e planos de corte para a resolucao de problemas maiores.
Enfermedad renal diabética: actúe ahora o pague luego. Día Mundial del Riñón 11 de Marzo 2010

Día Mundial del Riñón 11 de Marzo 2010: debemos actuar sobre la enfermedad renal diabética. En 2003, la Sociedad Internacional de Nefrología (ISN en inglés) y la Federación Internacional de Diabetes (IDF en inglés) lanzaron un folleto llamado “Diabetes en el Riñón: Tiempo de actuar” (1), para enfatizar la pandemia global de diabetes tipo 2 y de enfermedad renal diabética. Su propósito fue alertar a los gobiernos, organizaciones de salud, proveedores, médicos y pacientes, sobre los crecientes problemas causados por la enfermedad renal diabética y sus secuelas, la enfermedad renal terminal que requiere diálisis y la muerte cardiovascular. Siete años después, el mismo mensaje se ha vuelto más urgente. El Día Mundial del Riñón 2010, bajo el auspicio de la ISN y la Federación Internacional de Fundaciones Renales (IFKF en ingles), junto con la IDF, brinda una nueva oportunidad para subrayar la importancia de la enfermedad renal diabética, destacar la falta de concientización tanto a nivel público como gubernamental y enfatizar que su manejo implica su prevención, así como su reconocimiento y tratamiento de sus complicaciones. La prevención primaria de la diabetes tipo 2 necesitará cambios masivos de estilo de vida en el mundo en desarrollo y desarrollado, apoyados por un compromiso gubernamental fuerte para promover cambios sociales y de estilo de vida.
The curative potential of chimeric antigen receptor T-cell therapy for B-cell malignancies

Few cancers arising in fluid organ systems can be cured with localized therapeutic modalities, such as radiation or surgical organ removal. Chemotherapy and hematopoietic stem cell transplants have long been employed as the standard of care for patients diagnosed with leukemias and lymphomas. Though research continues to propose new, more potent chemotherapeutic agents, a new paradigm of treating cancerous malignancies with tumor-specific monoclonal antibodies, adoptively transferred tumorfighting cells, and other exogenously administered immunomodulatory agents, has emerged over the past decade. These immunotherapies have dramatically improved the outcomes of patients diagnosed with cancers of B lymphocytes, referred to as B-cell malignancies. Though curative FDA-approved therapies for patients diagnosed with B-cell malignancies have yet to be established, recent research in the field of adoptive T-cell therapy has produced promising results. Tumor infiltrating lymphocyte therapy (TIL therapy), T-cell Receptor Therapy (TCR therapy) and Chimeric Antigen Receptor T-cell Therapy (CAR T-cell therapy) are the three most extensively studied adoptive T-cell immunotherapies in the context of B-cell malignancies. TIL and TCR therapies, in which patients are provided with either the patient’s own tumor-specific T-cells or T-cells expressing engineered, tumor-specific TCRs, respectively, enhance the patient’s immune
Object recognition technology for autonomous unmanned control based on stereo data analysis and voxel representation of visible objects

The paper represents a description of the object recognition technology on a road using moving stereo pair of cameras in real time. The developed algorithm is characterized by high processing speed and performs reliable detection of arbitrary shape obstacles. Calculation time for one iteration from receiving input images (size 1280 * 480) to detecting obstacles is less than 2 msec for a Geforce GTX 1080T video card.
Predictive Factors for Occult Contralateral Papillary Thyroid Carcinoma in Patients with Ipsilateral Multifocality on Frozen Biopsy

Received March 29, 2017 Revised June 12, 2017 Accepted June 14, 2017 Address for correspondence Seung Won Lee, MD, PhD Department of OtorhinolaryngologyHead and Neck Surgery, Soonchunhyang University College of Medicine, 170 Jomaru-ro, Bucheon 14584, Korea Tel +82-32-621-5450 Fax +82-32-621-6950 E-mail lsw0922@naver.com Background and ObjectivesZZPapillary thyroid carcinoma (PTC) frequently occurs as multifocal and bilateral tumors. However, multifocality and bilaterality are not easy to detect preoperatively and contralateral remnant tumor might lead to reoperation after hemithyroidectomy. We aimed to demonstrate the frequency of bilaterality and predictive factors for occult contralateral PTC when a frozen biopsy of hemithyroidectomy shows multifocal PTCs in one of the lobes. Subjects and MethodZZOne hundred and thirty patients with PTC were enrolled in this study. All patients underwent hemithyroidectomy and frozen biopsy, followed by total thyroidectomy because of ipsilateral multifocality. Medical records, pathologic results, and preoperative ultrasound results were reviewed retrospectively. Patients were divided into two groups depending on bilaterality (unilateral or bilateral). ResultsZZBilaterality was detected in 74 of 130 patients (56.9%). Bilateral group showed more number of carcinomas (3.9±1.4 vs. 2.3±0.9) and more tendency of existence of contralateral nodule (87.8% vs. 55.3%). Tumor size of 1 cm or more and contralateral nodules were significant predictive factors for the existence of occult contralateral PTC. The suspicious sonographic feature of contralateral nodule had 75.7% sensitivity and 75% specificity for detecting bilaterality. ConclusionZZThe incidence of bilateral PTC is high in patients with ipsilateral multiple tumors. When the frozen biopsy result shows multifocality in one of the lobes, the remnant tumor may lead to reoperation under recent guidelines on thyroid surgical extent. Characteristics of contralateral nodule can help physicians and patients to make the decision regarding surgical extent. Korean J Otorhinolaryngol-Head Neck Surg 2017;60(10):517-21
Optimal Placement of Constant Power Loads at Different Buses of a DC Microgrid Ensuring Maximum Stability Margins

When a constant power load (CPL) is fed from a dc bus through an LC network, oscillations are observed in the input voltage of the CPL owing to its negative resistance property. These oscillations, if uncontrolled, amplify in magnitude leading to system instability. The behavior of multiple such CPLs connected to a dc microgrid is studied in this article. It has been found that CPLs experience a higher stability margin at the buses with renewable energy sources rather than at the buses with energy storages. This phenomenon is justified by deriving the equivalent resistance seen by the CPLs at the respective buses. In addition, for a large dc microgrid system with multiple buses, the particle swarm optimization algorithm is utilized to predict the best buses in the dc microgrid to connect the CPLs. This has been achieved by formulating an eigenvalue-based objective function. Experimental results obtained from a 4-bus 400-W dc microgrid prototype validate the efficacy of the proposed optimization.
Improving the Accuracy of Battery-Free Multiturn Absolute Magnetic Encoders by Using a Self-Referencing Lookup Table Algorithm

This article presents a self-referencing lookup table (LUT) algorithm to enhance the multiturn accuracy of a battery-free multiturn absolute magnetic encoder. The encoder consists of a single-turn angle for the measurement of the degree of rotation within $2\pi $ using a multipolar magnet to achieve high resolution and a multiturn counter to monitor the total number of revolutions made by the encoder’s shaft through the different angles of the four bipolar magnets (BPMs) based on four-shaft gears. However, the signals from the BPMs are affected by factors, such as amplitude mismatch, dc offsets, random noises, and harmonic components that are as a result of electrical and mechanical distortions. To solve this problem, this article suggested a method derived from the single-turn angle and the raw signals from the BPMs to generate the LUTs for multiturn angles. These angles eliminate the effects of the disturbances. Additionally, a multiturn compensation algorithm is suggested to compensate for the number of revolutions made by the encoder. The proposed methods are simulated in MATLAB software and implemented in ARM STM32F407ZG. The effectiveness of the proposed method is demonstrated by the obtained results.
Preschool Teachers’ Attitude Toward Inclusive Education in Central Java, Indonesia

This study aims to explore the knowledge and attitude of pre-school teachers regarding the implementation of inclusive education in Indonesia. This study involved 138 participants consisting of principals, curriculum developers and teachers in Central Java province, Indonesia. We used both open and closed questionnaires to collect data on their understanding and attitude toward inclusive education. The results revealed pre-school teachers’ positive attitude and high acceptance response for children with special needs at their schools. However, teachers reported difficulties in handling children with special needs due to their lack of adequate knowledge and skills in managing learning in an inclusive education setting. Teachers needed special training to improve their professional competence to handle children with special needs and assist their learning process in an inclusive classroom.