Miracle-dz/UniFAR-FTUs huggingface dataset:
A survey on text mining techniques

text mining is a technique to find meaningful patterns from the available text documents. The pattern discovery from the text and document organization of document is a well-known problem in data mining. Analysis of text content and categorization of the documents is a complex task of data mining. In order to find an efficient and effective technique for text categorization, various techniques of text categorization and classification is recently developed. Some of them are supervised and some of them unsupervised manner of document arrangement. This presented paper discusses different method of text categorization and cluster analysis for text documents. In addition of that a new text mining technique is proposed for future implementation.
Does dietary supplementation of cod liver oil mitigate musculoskeletal pain?

OBJECTIVE To investigate the relationship between dietary supplementation of cod liver oil and the intensity of pain in people with musculoskeletal pain. DESIGN Cross-sectional study. SETTING Data from the Norwegian Health Survey 1985. SUBJECTS All adult respondents who had reported musculoskeletal pain (n = 4490). MAIN OUTCOME MEASURES Intensity of musculoskeletal pain as assessed by self reports during an interview. RESULTS In logistic regression analyses (adjusting for age, gender, socioeconomic status, civil status, smoking habits, physical exercise, mental distress, and use of medicines), there was a negative association between regular intake of cod liver oil during the previous week and intense pain (OR = 0.75; 95% CI: 0.56-1.00; P = 0.048) and considerable/intense pain (OR = 0.81; 95% CI: 0.67-1.00; P = 0.045). The association was stronger in the 33% of the respondents who reported a musculoskeletal disease, as expressed by the relationship of cod liver oil to intense pain (OR = 0.64; 95% CI: 0.43-0.95; P = 0.028) and considerable/intense pain (OR = 0.74; 95% CI: 0.54-1.03; P = 0.076). The association varied between diagnostic groups, and was not seen in people who did not report a musculoskeletal disease. CONCLUSION The study suggests that people with musculoskeletal pain experience less pain if they take cod liver oil.
Tumor protein D52 (TPD52) is overexpressed and a gene amplification target in ovarian cancer

Recurrent chromosome 8q gain in ovarian carcinoma is likely to reflect the existence of multiple target loci, as the separate gain of chromosome bands 8q21 and 8q24 has been reported in independent studies. Since tumor protein D52 (TPD52) has been identified as a chromosome 8q21 amplification target in breast and prostate carcinoma, we compared TPD52 expression in normal ovarian epithelium (n = 9), benign serous adenomas (n = 11), serous borderline tumors (n = 6) and invasive carcinomas of the major histologic subtypes (n = 57) using immunohistochemistry. These analyses revealed that all normal ovarian epithelium samples and benign serous tumors were predominantly TPD52‐negative, whereas TPD52 was overexpressed in most (44/57; 77%) ovarian carcinomas regardless of histologic subtype. TPD52 subcellular localization was predominantly cytoplasmic, although nuclear localization was also frequently observed in mucinous and clear cell carcinomas. In an independent cohort of stage III serous carcinomas (n = 18), we also directly compared in situ TPD52 expression using immunohistochemistry and TPD52 copy number using interphase FISH analyses. This revealed that TPD52 dosage and TPD52 expression were significantly positively correlated. TPD52 therefore represents a novel molecular marker in ovarian cancer, which is broadly expressed across the different histologic subtypes and whose upregulation frequently reflects increased TPD52 copy number. © 2005 Wiley‐Liss, Inc.
Importance of needle age and shoot structure on canopy net photosynthesis of balsam fir (Abies balsamea): a spatially inexplicit modeling analysis.

We have developed a spatially inexplicit model of canopy photosynthesis for balsam fir (Abies balsamea (L.) Mill. ) that accounts for key processes of light-shoot interaction including irradiance interception by the shoot, spatial aggregation of shoots into branches and crowns, the differential propagation of diffuse and direct light within the canopy, and an ideal representation of penumbra. Also accounted for in the model are the effects of the average radiative climate and shoot age on needle retention, light interception, and photosynthetic capacity. We used reduced versions of this model to quantify the effects of simplifying canopy representation on modeled canopy net photosynthesis. Simplifications explored were the omission of direct beam transformation into penumbral light and the use of different constant shoot properties throughout the canopy. The model was parameterized for a relatively dense balsam fir stand (leaf area index of 5.8) north of Québec City, Canada, and run using hourly meteorological data obtained at the site. The overall performance of the complete model was satisfactory, with maximum values of canopy net photosynthesis of 23 micromol (m(2) ground)(-1) s(-1) (83 mmol m(-2) h(-1)), and a near-saturation of the canopy at a photosynthetically active radiation photon flux density of about 750 micromol m(-2) s(-1) (2.7 mol m(-2) h(-1)). The omission of penumbral effects through the use of unattenuated direct (beam) radiation at all layers of the canopy, as used for broad-leaved species, reduced canopy net photosynthesis by 3.7%. Analysis of the results show that the small impact of penumbra on canopy net photosynthesis stems from the high proportion of diffuse radiation (73%) estimated from our meteorological data set; single-hour results under clear sky conditions approach theoretical bias values of about 30%. Use of mean shoot photosynthetic, light capture and light transmission properties throughout the canopy biased canopy net photosynthesis by less than 3%. However, simulations carried out based on properties of 1-year-old shoots throughout the canopy overestimated canopy net photosynthesis by 9%. Use of the shoot as our smallest functional unit was a potential source of bias because the differential absorption of direct and diffuse radiation within the shoot could not be factored into the model. Other sources of potential bias are discussed.
Interproximal Papillae Adjacent to Single Implant Crowns in the Aesthetic Zone: Clinical and Radiographic Findings from a Multi-private Practice Based Research Network (PBRN) and Post-graduate Prosthodontics/Periodontology Residency Programs

This study was designed to determine if the following two variables influence the predictability of the presence of the interproximal papilla between single implant supported crown adjacent to a natural tooth: a) the vertical measurement from the crest of bone on the natural tooth to the contact point, and b) the horizontal measurement from the platform of the implant to the adjacent tooth root. Retrospective data from a multi-private practice based research network (PBRN) and from a graduate teaching institution were analyzed specific to the maxillary anterior aesthetic zones. 116 patients who had 139 dental implants restored for at least 6 months, with mesial and/or distal sites (N= 253) were included in the analysis. Assessments of the implant position based on osseous crestal topography were conducted using standardized radiographs which were digitized and interpreted with “Access” software. The gingival papilla morphology was assessed using the Jemt Papillary Index from calibrated digital clinical photographs. Contrary to previously published data, our results indicate that the presence of interproximal papillae is independent of the vertical and horizontal measurements investigated.
Laboratory-based surveillance for rotavirus -- United States, July 1996-June 1997.

Rotavirus infections are the most common cause of severe gastroenteritis among infants and young children worldwide. Each year in the United States, rotavirus infections account for an estimated 3.5 million cases of diarrhea, 500,000 physician visits, 50,000 hospitalizations, and 20 deaths among children aged <5 years. In addition, rotavirus accounts for 30%-50% of U.S. hospitalizations for diarrhea among children aged <5 years, including approximately 50% of hospitalizations for diarrhea during annual seasonal peaks, and is an important cause of nosocomial gastroenteritis. Rotavirus activity in the United States is monitored by the National Respiratory and Enteric Virus Surveillance System (NREVSS), a voluntary, laboratory-based system. This report summarizes surveillance from NREVSS during July 1996-June 1997.
Treatment of malignant glioma using hyperthermia

Thirty pathologically diagnosed patients with grade III–IV primary or recurrent malignant glioma (tumor diameter 3–7 cm) were randomly divided into two groups. The control group underwent conventional radiotherapy and chemotherapy. In the hyperthermia group, primary cases received hyperthermia treatment, and patients with recurrent tumors were treated with hyperthermia in com-bination with radiotherapy and chemotherapy. Hyperthermia treatment was administered using a 13.56-MHz radio frequency hyperthermia device. Electrodes were inserted into the tumor with the aid of a CT-guided stereotactic apparatus and heat was applied for 1 hour. During 3 months after hyperthermia, patients were evaluated with head CT or MRI every month. Gliomas in the hyper-thermia group exhibited growth retardation or growth termination. Necrosis was evident in 80% of the heated tumor tissue and there was a decrease in tumor diameter. Our findings indicate that ra-dio frequency hyperthermia has a beneficial effect in the treatment of malignant glioma.
Phosphatase CD45 Both Positively and Negatively Regulates T Cell Receptor Phosphorylation in Reconstituted Membrane Protein Clusters*♦

Background: The roles of protein clustering in T cell signaling are poorly understood. Results: Lck clustering recreates conditions in which a phosphatase has positive and negative roles in signal initiation. Conclusion: Autoinhibition due to Lck clustering is relieved by an optimal concentration of CD45. Significance: A novel regulatory mechanism of protein clustering other than increasing local concentration has been discovered. T cell receptor (TCR) phosphorylation requires the kinase Lck and phosphatase CD45. CD45 activates Lck by dephosphorylating an inhibitory tyrosine of Lck to relieve autoinhibition. However, CD45 also dephosphorylates the TCR, and the spatial exclusion of CD45 from TCR clustering in the plasma membrane appears to attenuate this negative effect of CD45. To further investigate the role of CD45 in signal initiation, we reconstituted membrane TCR clusters in vitro on supported lipid bilayers. Fluorescence microscopy of single clusters showed that incorporation of CD45 enhanced phosphorylation of TCR clusters, but only when Lck co-clustered with TCR. We found that clustered Lck autophosphorylated the inhibitory tyrosine and thus could be activated by CD45, whereas diffusive Lck molecules did not. In the TCR-Lck clusters and at low CD45 density, we speculate that the effect of Lck activation may overcome dephosphorylation of TCR, resulting in a net positive regulation. The CD45 density in physiological TCR clusters is also low because of the exclusion of CD45. Thus, we propose that the spatial organization of TCR/Lck/CD45 in T cell membranes is important not only for modulating the negative role of CD45 but also for creating conditions in which CD45 has a positive role in signal initiation.
Different Porphobilinogenases in Cytoplasm and Isolated Chloroplasts from Light-Grown Euglena gracilis Z.

Abstract Lysed cells as well as different fractions of isolated, disrupted chloroplasts from light grown Euglena gracilis were tested for their capability of porphyrin biosynthesis. It is shown that the formation of the soluble porphobilinogenase (PBG-ase) fraction is inhibited by cycloheximide indicating its biosyntheses on 80S ribosomes, whereas the formation of the membrane bound chloroplast PBG-ase is chloramphenicol sensitive. Different pH-optima are demonstrated for the two enzymes. From the presented results it is deduced from those isolated from dark grown cells.
Studies on injury and repair of donor bile ducts after liver transplantation

Biliary complications, especially nonanastomotic strictures (NAS), are a major cause of morbidity after orthotopic liver transplantation. Of all donor and recipient characteristics known to increase the risk of developing NAS, the role of prolonged ischemia times is most extensively described in the literature. However, there is increasing evidence that several other, non-ischemia-related factors play a critical role in the pathogenesis of NAS as well. The clinical presentation of NAS may vary considerably among livertransplant recipients, including large variations in time of occurrence, and in location and severity of the strictures. Additional underlying causes such as bile salt toxicity and immune-mediated injury are believed to explain the wide spectrum of biliary strictures after orthotopic liver transplantation. Current and emerging insight in the pathogenesis of NAS and potential targets to reduce biliary injury and preserve bile ducts are discussed in this overview.
Triplex DNA: RNA, 3′-to-5′ Inverted RNA and Protein Coding in Mitochondrial Genomes

Triple-stranded DNA:RNA helices of unknown function in vertebrate mitochondria associate with replication and transcription. Antiparallel Hoogsteen pairings form triplexes at physiological conditions. Intermolecular antiparallel triplexes require inverted 3'-to-5' RNA polymerization, which was never observed. Three rare, long natural 3'-to-5' inverted GenBank RNAs from mice mitochondria suggest occasional inverted transcription, putatively coding for proteins. BLAST aligns 18 GenBank-stored proteins with hypothetical proteins translated from the 3'-to-5' inverted Mus musculus mitochondrial genome. Three are DNA-binding, five are membrane proteins. 25% of main frame codons contribute to their 3'-to-5' overlap coding. Properties of these codons match those of overlap coding protein genes, as compared to codons not expected involved in inverted coding: a) nucleotide contents at synonymous codon positions in mitochondrial genomes fit replicational deamination gradients (A->G and C->T), but digress from gradients when functioning as nonsynonymous positions in putative 3'-to-5' overlapping genes; b) bias against 'circular code' codons (codon groups creating unambiguity between frames), and favouring homogenous codons (AAA, CCC, GGG, TTT) characterize overlapping genes, including putative 3'-to-5' overlapping genes, as compared to nonoverlapping coding sequences from the same main frame gene. This signature correlates with digression from deamination gradients. Deamination and circular code tests confirm independently alignment-based predictions of overlapping 3'-to-5' protein coding genes. Results indicate varying expression for different 3'-to-5' overlapping genes. Inverted 3'-to-5' RNA is produced, perhaps by an unknown RNA polymerase (invertase) putatively coded by 3'-to-5' inverted RNA.
Role of Serotonin and Serotonin-Selective Pharmacotherapy in Alcohol Dependence

Abstract The majority of studies that have examined the usefulness of pharmacotherapies selective for serotonin (5-hydroxytryptamine; 5-HT) as a treatment for alcohol dependence have been standard, double-blind clinical trials that include patients with a variety of clinical presentations. Almost all of the early studies evaluated heavy social drinkers and found only a modest advantage for 5-HT pharmacotherapies in reducing the number of drinks per day. Also, the advantage of these pharmacotherapies was observed primarily when these agents were given at higher daily dosages than suggested prescribing practices for use as an antidepressant. The few studies that evaluated treatment-seeking patients found that 5-HT pharmacotherapies were not instrumental in reducing drinking rates compared with placebo. These results led to a dampening of enthusiasm for use of these agents in treating alcohol dependence. However, more recent investigations have begun to target subgroups with potential abnormalities in 5-HT neurotransmission. The thinking is that these medications should be most useful in alcohol-dependent individuals who have more clearly delineated suggestive signs of 5-HT dysfunction, such as concomitant depression or anxiety. Although few results are available to date, there is growing evidence to suggest that alcohol-dependent subgroups are differentially responsive to 5-HT pharmacotherapies with respect to drinking-related outcomes. This may explain the modest and variable 5-HT pharmacotherapeutic effects that were reported in the earlier studies, which included large heterogeneous patient groups. Further investigations are needed to confirm these initial optimistic results.
Integer-code DC fault dictionary

This paper addresses itself to computer-aided diagnosis of analog circuits by means of simulation-before-test approach, the so called dictionary approach. New method of dictionary construction is presented. The method combines three previously presented methods, namely: sensitivity based method of finding ambiguity sets in measurement space and corresponding binary signatures, information channel based method of finding minimum set of measurements and a method of the integer-code dictionary formulation, based on the introduced quasi Hamming distance between signatures.
Effects of 2,3‐Butanedione Monoxime on Atrial—Atrioventricular Nodal Conduction in Isolated Rabbit Heart

BDM Effects on AVN Conduction. Introduction: 2,3‐Butanedione monoxime (BDM) has been found to reversibly block cardiac contraction, without blocking electrical conduction. This study characterizes the dose‐dependent effects of BDM on the conduction through the atrioventricular node (AVN) of rabbit heart.
Social-insect-inspired adaptive task allocation for many-core systems

Large social insect colonies require a wide range of important tasks to be undertaken to build and maintain the colony. Fortunately, in most nests there are many thousands of workers available to offer their assistance to ensure the expansion and survival of the colony. However, there is a crucial equilibrium between the number of workers performing each task that must not only be maintained but must also continuously adapt to sudden changes in environment and colony need. What is most fascinating is that social insects can sustain this balance without any centralised control and with colony members that have relatively little intelligence when considered on their own. Due to this simplicity and evident scalability it would seem that social insects have evolved an interesting scalable approach to task allocation that could be applied to very large many-core systems. To investigate this we have explored biological models of task allocation in ant colonies and applied this to a 36-core Network on Chip. This paper not only shows that effective decentralised task allocation is achieved, but also that such a scheme can adapt to faults and alter its behaviour to meet soft real-time constraints. Therefore, it is established that social insect inspired intelligence models offer a suitable metaphor and development direction for tackling the challenges introduced by dark silicon and in-field faults in a decentralised and adaptive fashion.
DeMorgan systems on the unit interval

Logical connectives on fuzzy sets arise from those on the unit interval. The basic theory of these connectives is cast in an algebraic spirit with an emphasis on equivalence between the various systems that arise. Special attention is given to DeMorgan systems with strict Archimedean t‐norms and strong negations. A typical result is that any DeMorgan system with strict t‐norm and strong negation is isomorphic to one whose t‐norm is multiplication. © 1996 John Wiley & Sons, Inc.
Impact of clinical guidelines in the management of severe hospital-acquired pneumonia.

STUDY OBJECTIVES To asses the impact of locally developed antimicrobial treatment guidelines in the initial empiric treatment of ICU patients with severe hospital-acquired pneumonia (HAP). DESIGN Observational cohort study with pre-guideline and post-guideline data collection. PATIENTS A total of 48 pre-guideline patients with 56 episodes of severe HAP defined by the National Nosocomial Infections Surveillance (NNIS) compared with 58 guideline-treated (GUIDE) patients with 61 episodes of severe HAP. RESULTS The two groups were similar in terms of mean (+/- SD) age (NNIS group, 67.7 +/- 9.6 years; GUIDE group, 68.0 +/- 11.5 years) and simplified acute physiology score (NNIS group, 12.9 +/- 3.9; GUIDE group, 12.6 +/- 3.1) at the HAP diagnosis, and the proportion of the most frequent isolates (ie, Pseudomonas and methicillin-resistant Staphylococcus aureus). There was wide variation in initial antibiotic use in NNIS-treated patients, with cefotaxime, ceftazidime, and piperacillin being the most common agents compared with all of the GUIDE patients who received an imipenem-cilastin-based regimen. Vancomycin use was similar in both groups. The GUIDE patients had a higher percentage of adequately treated patients (81% vs 46%, respectively; p < 0.01) with a lower mortality rate at 14 days (8% vs 23%, respectively; p = 0.03). A lower mortality rate was also noted at the end of 30 days and the end of hospitalization but was not statistically significant. Appropriate imipenem use (as defined by the guidelines) occurred in 74% of the cases, and there was no increase in the number of imipenem-resistant organisms isolated during the course of the study. CONCLUSIONS These guidelines represent a successful implementation of a "deescalation" approach, because the recommended empiric therapy with broad-spectrum antibiotics was switched to therapy with narrower spectrum agents after 3 days. Based on our experience, this approach improves the adequacy of antibiotic treatment, with improvement in short-term survival and without increasing the emergence of resistant organisms.
Evaluation of egg yolk colour

Bovskova H. , Mikova K. , Panovska Z. (2014): Evaluation of egg yolk colour. Czech J. Food Sci., 32: 213–217. We compare visual evaluation of yolk colour estimated by the usual method applying La Roche scale with spectrophotometric determination of β-carotene by AOAC method, and by new rapid analyser iCheckTM Egg photometr (Bio Analyt). The eggs under consideration were purchased on a current Czech market. The eggs originated from various countries and various types of breeding including some specialities. The yolk colour varied between the values of 4–13 of La Roche scale. The carotenoid content expressed as β-carotene measured by AOAC method varied between 11–87 mg/kg. The carotenoid content expressed as β-carotene measured with the analyser iCheckTM Egg photometr was lower and varied between 7.5–68.5 mg/kg. The correlation between the colour hue measured visually and the carotenoid content was not proved. Slovak eggs from cages which contained 28.3 mg carotenoids in 1 kg of yolk had the darkest yolks (value 13), Czech bio eggs which contained 20.2 mg carotenoids in 1 kg of yolk had the palest yolks (value 6). The highest content of carotenoids was found in eggs from home hen breeding (72.5 mg carotenoids in 1 kg of yolk) whose colour hue had the value of 10.
Optimizing Position of Repeaters in Distributed MIMO Repeater System for Large Capacity

Multiple-input multiple-output (MIMO) repeater systems have been discussed in several published papers. When a repeater has only one antenna element, the propagation environment is called keyhole. In this kind of scenario the achievable channel capacity and link quality are decreased. Another limit is when the number of the antenna elements of a repeater is larger than that of a MIMO transceiver, the channel capacity cannot be increased. In this paper, in order to obtain an upper bound of the channel capacity, we express a propagation process of the distributed MIMO repeater system with amplify-and-forward method by the numerical formular, and optimize the position of each repeater.