Miracle-dz/UniFAR-FTUs huggingface dataset:
Immersive virtual reality vs. non-immersive distraction for pain management of children during bone pins and sutures removal: A randomized clinical trial protocol.

AIMS To examine the efficacy of an immersive virtual reality distraction compared with an active non-immersive distraction, such as video games on a tablet, for pain and anxiety management and memory of pain and anxiety in children requiring percutaneous bone pins and/or suture removal procedures. DESIGN Three-centre randomized clinical trial using a parallel design with two groups: experimental and control. METHODS Study to take place in the orthopaedic department of three children hospital of the Montreal region starting in 2019. Children, from 7-17 years old, requiring bone pins and/or suture removal procedures will be recruited. The intervention group (N = 94) will receive a virtual reality game (Dreamland), whereas the control group (N = 94) will receive a tablet with video games. The primary outcomes will be both the mean self-reported pain score measured by the Numerical Rating Scale and mean anxiety score, measured by the Child Fear Scale. Recalls of pain and anxiety will be measured 1 week after the procedure using the same scales. We aim to recruit 188 children to achieve a power of 80% with a significance level (alpha) of 5%. DISCUSSION While multiple pharmacological methods have previously been tested for children, no studies have evaluated the impact of immersive virtual reality distraction for pain and anxiety management in the orthopaedic setting. IMPACT Improved pain management can be achieved using virtual reality during medical procedures for children. This method is innovative, non-pharmacological, adapted to the hospital setting, and user-friendly. TRIAL REGISTRATION NCT03680625, registered on clinicaltrials.gov.
Flavonoids profile and antioxidant activity in flowers and leaves of hawthorn species (Crataegus spp.) from different regions of Iran

ABSTRACT This study was undertaken to determine the total quantity of phenolic and flavonoids, as well as to find out about the HPLC quantification of some individual phenolic compounds (i.e. chlorogenic acid, vitexin 2”-O-rhamnoside, vitexin, rutin, hyperoside, quercetin, and isoquercetin) in flowers and leaves of 56 samples of different hawthorn species (Crataegus spp.) collected from different geographical regions of Iran. The amount of total phenolics ranges from 7.21 to 87.73 mg GAE/g in dry weight of the plant, and the total amount of flavonoids varied amongst species and in different plant organs ranging from 2.27 to 17.40 mg/g dry weight. Chlorogenic acid, vitexin, and vitexin 2”-O-rhamnoside were found to be the most abundant phenolic compounds in the extracts of hawthorn leaves. Meanwhile, chlorogenic acid, hyperoside, and rutin were the most abundant phenolic compounds in the extracts of hawthorn flowers in most genotypes. The antioxidant activity widely varied in species and in different organs of each individual plant, ranging from 0.9 to 4.65 mmol Fe++/g DW plant, calculated through the ferric-reducing antioxidant power (FRAP) method. Thus, this could provide valuable data for developing breeding strategies and plans; it can also help us in selecting genotypes with high phenolic contents for producing natural antioxidants and other bioactive compounds beneficial for food or the pharmaceutical industries.
Morphological, Chemical, and Biological Investigation of Ionic Substituted, Pulse Current Deposited Calcium Phosphate Coatings

Ionic substituted calcium phosphate coatings (iCP) have been prepared by the electrochemical pulse current deposition technique with an alternate pulse on and off time of 5 ms onto a titanium alloy substrate. The elemental distribution and morphology of the deposited layers have been extensively studied by scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), and transmission electron microscopy (TEM). The crystallinity and phase structure of iCPs have been investigated by X-ray diffraction (XRD). The corrosion characteristics and biodegradability of coatings have been determined by electrochemical measurements, recording potentiodynamic curves in a physiological solution over a long-term immersion period. The cell viability tests confirmed that the iCP coating was biocompatible, while the corrosion tests proved its biodegradable characteristic. In our paper, we compare the morphological, chemical, and biological characteristics of silver and zinc substituted calcium phosphate layers deposited by the electrochemical method.
ReNets: Statically-Optimal Demand-Aware Networks

This paper studies the design of self-adjusting datacenter networks whose physical topology dynamically adapts to the workload, in an online and demand-aware manner. We propose ReNet , a self-adjusting network which does not require any predictions about future demands and amortizes reconfigurations: it performs as good as a hypothetical static algorithm with perfect knowledge of the future demand. In particular, we show that for arbitrary sparse communication demands, ReNets achieve static optimality , a fundamental property of learning algorithms, and that route lengths in ReNets are proportional to existing lower bounds, which are known to relate to an entropy metric of the demand. ReNets provide additional desirable properties such as compact and local routing and flat addressing therefore ensuring scalability and further reducing the overhead of reconfiguration. To achieve these properties, ReNets combine multiple self-adjusting tree topologies which are optimized toward individual sources, called ego-trees in this paper.
Brazing Inconel 625 for Plate Heat Exchanger

The purpose of this research is developing plate heat exchanger for special applications. The technology of manufacturing plate heat exchangers is much more difficult than that of making traditional heat exchangers. The plate heat exchanger is currently made by Cu brazing for most major heat exchanger manufacturer in the world. Stable brazing process and inexpensive filler alloy are primary advantages of Cu brazing. However, requirements of increased corrosion resistance, avoiding Cu ion contamination, resisting to high temperature and pressure resulting from various users make the Cu brazed stainless steel plate heat exchanger fail to satisfy all applications. Two novel amorphous Ni/(Fe)-based fillers are successfully applied in brazing IN-625 plate heat exchangers, and significantly improve the corrosion resistance of Cu brazed stainless steel plate heat exchanger. It is valuable for industrial applications.
Eff ect of Surface Roughness and Joint Clearance on Microstructure and Interfacial Strength of 304 Stainless Steel Joints Brazed with BNi-2

Brazing is a joining process depending on melting, flow and solidification of filler material to form metallurgical bond between filler and base component. From the various brazing filler materials (BFMs), Nibased BFMs are commonly used in high temperature applications and corrosive environments. In this study, AISI 304 stainless steel pieces with different roughness values were brazed under vacuum brazing furnace using nickel based BNi-2 filler material. Different surface treatments were applied to alter the surface roughness of steel pieces; namely, sand blasting, grinding, polishing and electropolishing. Mechanical properties were identified with tension test and microstructural characterization was done with scanning electron microscopy (SEM). The results indicate that with increasing roughness of the base material enhanced the interfacial strength up to a certain roughness level.
Effect of Trihoney (A Mixture of Trigona, Mellifera and Tualang) on Male Reproductive Hormones and Insulin Resistance in Hypercholesterolaemic Rabbits

Introduction: Hypercholesterolaemia affects Sertoli and Leydig cells secretory functions, impairs steroidhormone biosynthesis, and disrupts the hypothalamic-pituitary-gonadal axis. The use of honey in previousstudies resulted in an improvement of male reproductive hormonal disturbances. This study aimed toinvestigate the protective effects of Trihoney on hypercholesterolemia-induced male reproductive hormonalchanges in male rabbits and compare its effects with atorvastatin. Materials and methods: Forty-eight maleNew Zealand white rabbits were assigned into 6 groups as follows; Control: commercial pellet; CH:commercial pellet with 0.6 g/kg/day Trihoney; HCD: 1% cholesterol diet; DH1: 1% cholesterol diet with 0.3g/kg/day Trihoney; DH2: 1% cholesterol diet with 0.6 g/kg/day Trihoney and DAt: 1% cholesterol diet with2mg/kg/day atorvastatin. After 12 weeks, the rabbits were sacrificed and blood samples were collected foranalysis of hormones and pro-inflammatory cytokines and calculation of HOMA-IR. The testes werehomogenized for intra-testicular testosterone measurement. Results: Serum testosterone reducedsignificantly in HCD (p<0.05) and DAt (p<0.05) groups. Likewise, intra-testicular testosterone reducedsignificantly in HCD (p<0.01) and DAt (p<0.01) groups. Serum FSH increased significantly in HCD (p<0.001)and DAt (p<0.01). Trihoney particularly at the dose of 0.6 g/kg/day improved serum and intra-testiculartestosterone (p<0.05) and FSH (p<0.05). Trihoney and atorvastatin improved serum pro-inflammatorycytokines. Trihoney and atorvastatin did not affect HOMA-IR. Conclusion: Trihoney attenuated thedetrimental effects of hypercholesterolaemia on male reproductive hormones which probably through alocal effect on testicular tissue and Trihoney anti-inflammatory effect independent of insulin resistance.Atorvastatin did not counteract the impact of hypercholesterolaemia on the reproductive hormones.
Docking Studies on Potential Mechanisms for Decreasing Insulin Resistance by the Tangzhiqing Herbal Formula

Insulin resistance (IR) is considered as one of the principal pathways of type 2 diabetes mellitus pathogenesis and is associated with a series of abnormal signaling pathways. Tangzhiqing (TZQ) herbal formula is a well-known antidiabetic traditional Chinese medicine and has been used to treat type 2 diabetes mellitus and prediabetes for many years in China. We selected 13 natural products as representative compounds of the main active components in TZQ to investigate the interaction of these natural products with key signal proteins associated with IR using two different docking calculations. Salvianolic acids A and C (phenolic acids from Salvia miltiorrhiza), rutin (a flavonoid from Morus alba), paeoniflorin (a saponin from Paeonia lactiflora), and quercitrin (a flavonoid from Crataegus pinnatifida) showed great docking abilities towards multiple target proteins. These results have contributed to a clearer understanding regarding the regulation mechanism of TZQ on IR and have provided direction for further pharmacological studies.
Assessment of corrosion processes in steel orthodontic archwires – in vitro studies

Dane do korespondencji/correspondence address: Zakład Ortodoncji Uniwersytetu Medycznego w Łodzi ul. Pomorska 251 90-001 Łódź e-mail: konrad.malkiewicz@interia.pl Wkład autorów: A Plan badań B Zbieranie danych C Analiza statystyczna D Interpretacja danych E Redagowanie pracy F Wyszukiwanie piśmiennictwa Authors’ Contribution: A Study design B Data Collection C Statistical Analysis D Data Interpretation E Manuscript Preparation F Literature Search
Knowledge and behavior of Saudi women regarding osteoporosis prevention based on the health belief model

Osteoporosis remains a global health problem. An osteoporosis-related fracture associated with significant morbidity, mortality, and health care costs. Bone health is becoming a serious concern in the kingdom as the prevalence of osteoporosis is expected to ANALYSIS 24(104), July August, 2020 Medical Science ISSN 2321–7359 EISSN 2321–7367
Measurement of the ω → π + π − π 0 Dalitz plot distribution The WASA-at-COSY Collaboration

Using the production reactions pd → 3Heω and pp → ppω, the Dalitz plot distribution for the ω → π+π−π0 decay is studied with the WASA detector at COSY, based on a combined data sample of (4.408 ± 0.042) × 104 events. The Dalitz plot density is parametrised by a product of the P-wave phase space and a polynomial expansion in the normalised polar Dalitz plot variables Z and φ. For the first time, a deviation from pure P-wave phase space is observed with a significance of 4. 1σ. The deviation is parametrised by a linear term 1 + 2αZ, with α determined to be +0.147 ± 0.036, consistent with the expectations of ρ-meson-type final-state interactions of the P-wave pion pairs.
Thermal Motion 1 Introduction and Historical Facts

The most famous description of Brownian Motion was given by the botanist Robert Brown in 1828.His first speciments were of ’live’ pollen grains (he believed that pollen grains were alive). To his credit, he did show that inorganic as well as organic objects produced the same movements, and more importantly, demonstrated that the phenomenon was not due to convective currents or other experimental artifacts. Nevertheless, Brown still clung to the notion that the cause of the motion was some unknown active molecules internal to the particles and not in the surrounding fluid [1]. In 1905, Einstein, then an industrious patent clerk, produced a series of work on the elementary theory of Brownian motion (and also found time to hypothesize the photon and invent the theory of special relativity). Remarkably, he completed the first paper without ever having seen Brownian motion himself. The paper begins [2]:
Identification of functional modules relevant to human neuron maturation and generation of neuron maturity index

Neuron maturation is a critical process in neurogenesis, during which neurons gain their morphological, electrophysiological and molecular characteristics for their functions as the central components of nervous system. To better understand the molecular changes during such process, we integrated protein-protein interaction network and public single cell RNA-seq data of mature and immature neurons to identify functional modules whose activities are relevant to neuron maturation process in humans. Based on the identified modules, we further developed and validated a machine learning based metric of neuron maturity, namely neuron maturity index (NMI). This work provides new frameworks for functional module identification as well as quantifications of neuron maturity state in single neuron or purified neuron RNA-seq data.
Effect of Pelletized Diets and the Proportion of Fines on Performance of Broilers Raised in High‐Density Conditions

SUMMARY The objective of the study was to evaluate some important parameters regarding production and welfare, as well as performance, uniformity, carcass yield and foot‐pad lesions of broilers fed mash or pelleted diets with different concentrations and raised in different density conditions. The experimental design consisted of a 3 × 2 factorial scheme (3 diets: mash feed, pelleted feed with 50% of fines, and pelleted feed with 30% of fines vs. 2 stocking densities: 13 and 15 birds/m2) with six replications, totaling 1,746 male Cobb chicks. Besides the weight of the birds and feed intake for each replicate assessed weekly to evaluate performance, at 7 and 42 d of age all birds were individually weighed to assess uniformity within each replicate. Moreover, 12 birds/treatment were slaughtered to assess the yield for carcass and commercial cuts. To assess the incidence of food‐pad dermatitis (FPD), all birds were evaluated for lesion score at 21 and 42 d of age. The intake of pelleted diets resulted in greater body weight gain and better feed conversion ratio in the first week. The reduction of stocking density resulted in greater weights of carcasses, legs, and wings as well as wing yield at the 46th day but did not alter FPD incidence. The performance during the grower/finisher phase and during all production phases was not affected by diet and stocking density, despite the greater performance that was observed for chicks supplemented with pelleted and ground diets in the starter phase.
Australopithecus Sediba, Statistical Baraminology, and Challenges to Identifying the Human Holobaramin

The recent discovery and description of Australopithecus sediba proved controversial among creationists after Wood (2010) broke with the majority and proclaimed it human based on an analysis of craniodental characters using statistical baraminology. Since creationists often judge postcranial characters more significant than craniodental characters, a re-analysis of the hominin holobaramin was undertaken using 78 postcranial characters published by Berger, et al. (2010) and 25 characters of the hand published by Kivell, et al. (2011). These character sets, along with subsets of the original craniodental characters evaluated by Wood (2010) were used to calculate baraminic distance correlations (BDC) and multidimensional scaling (MDS). The inconclusive results raise questions about the value of using correlation and clustering methods to identify holobaramins.
Dynamic Partial State Feedback Trajectory Tracking of the Unicycle Mobile Robot

Resumen —In this paper we address and propose a solution to the problem of trajectory tracking for the kinematic model of the unicycle mobile robot by means of dynamic partial state feedback. The proposed controller is designed by combining a classical dynamic full information controller with an exponentially stable angular attitude estimator, based on the immersion and invariance technique. Numerical simulations complete the paper.
Flow During Friction Stir Welding of Ti-6 Al-4 V

6 mm thick Ti-6Al-4V butt joints were produced with a tracer material embedded in the joint under a variety of process conditions, namely rotational speed and traversing speed, in an attempt to relate the welding process parameters to the material flow behavior via post weld radiographic and metallographic evaluations. It was found that by embedding refractory alloy powder into the joint line, welding through it, and subsequently x-raying the joint, the material flow patterns could be examined. The tracer material was distributed over a wider area in the weld zone relative to its starting position, implying a fair amount of mixing occurred even though little vertical movement of the tracer material was observed. There was minimal effect of material flow patterns as a function of welding parameters observed using the tracer material and radiographic examination, but defect formation in the root, where there was no tracer material, examined by cross sectional metallographic evaluations were found to be dependent on the rotational speed and traversing speed conditions. Lack of penetration defects were generally associated with relatively “cold” welding conditions (low rotational speed/high traversing speeds) and voids with “hot” conditions (high rotational speed/low traversing speeds).
Finite frequency H ∞ control for jump systems over given time interval

Finite frequency H∞ control for jump systems over given time interval ZHOU Chao-jie, LUAN Xiao-li†, LIU Fei (Key Laboratory for Advanced Process Control of Light Industry of the Ministry of Education, Institute of Automation, Jiangnan University, Wuxi Jiangsu 214122, China) Abstract: To guarantee the state trajectories of different modes stay within the desired bound in given time interval and have better disturbance rejection level, the given time controller is designed for jump systems subject to external disturbances with specific frequency. The proposed control scheme provides new thought for reducing engineering conservation of controller design for jump systems not only from the perspective of time, but also from frequency domain by introducing frequency information into controller design. Simulation example verifies the effectiveness and advantages of the proposed algorithm.
Die Regulation der Camalexinbiosynthese in Arabidopsis thaliana

Camalexin ist das charakteristische Phytoalexin von Arabidopsis thaliana . Bei Pathogeninfektion wird die Synthese von Camalexin z. B. durch die Erkennung von Peptidoglycan oder Nep1-artigen Proteinen (NLPs) ausgelost. Pflanzen, welche ein NLP unter der Kontrolle eines Ethanol-induzierbaren Promotors exprimieren zeigten eine starke Induktion der Tryptophan- und Camalexinbiosynthesegene und eine reproduzierbare Camalexinakkumulation. Retrobiosynthetische NMR-Analysen und Markierungsexperimente mit direkten Vorstufen belegten, dass das bakterielle Camalexin-Derivat BE-10988 aus Streptomyces, wie Camalexin aus Tryptophan und Cystein synthetisiert wird.
FORECASTING THE DISTRIBUTION OF PRECIPITATE DIAMETERS IN THE PRESENCE OF CHANGES IN THE STRUCTURE OF THE MATERIAL

The results of investigations on the microstructure of T23 and T24 low-alloy steels as well as P91 and P92 high-chromium steels in the as-received condition and after 70.000 h annealing at 550-650°C are presented. The quantitative analysis of the existing precipitates was performed for representative images of microstructure. The statistical analysis of collected data allowed the parameters of a selected theoretical statistical distribution to be estimated. A forecast of average precipitate diameter and standard deviation of such a distribution for the time of 100,000 hours at 550 and 600°C for T23 and T24 steels and at 600 and 650°C for P91 and P92 steels was calculated. The obtained results of investigations have made it possible to compare changes in the microstructure of various steel grades due to long-term impact of elevated temperature. They have also confirmed the possibility of using, in evaluating the degradation degree of materials in use, the forecasting methods that derive from mathematical statistics, in particular the theory of stochastic processes and forecast by analogy methods. The presented approach allows the development of a forecast of precipitate diameter probability density under the microstructure instability conditions for selected steel grades. The assessment of material condition that takes into consideration, but is not limited to, the precipitate diameter measurement is useful as an assessment component in estimating the time of safe service of power unit elements working under creep conditions.
Evaluation of EAP in a Rotating Detonation Combustor

The last decade has seen a renewed interest in Rotating Detonation Engine (RDE) technology and its potential benefits for energy conversion and propulsion application. Significant progress has been made to understand the operational characteristics of RDEs, and some work has evaluated the performance that can be achieved by an RDC, and its ability to generate net positive pressure gain. Currently there is no universally agreed upon method for defining or quantifying pressure gain within a device experimentally or computationally. Kaemming and Paxson have proposed the the concept of Equivalent Available Pressure (EAP) as a means of estimating the total pressure gain produced by an RDE [1]. By using this quantity under the approximation that the flow is steady and homogeneous, a pressure gain combustor can be more readily compared to a deflagration-based combustor under similar operating conditions. In the past few years there have been several experimental studies that have measured EAP in different configurations and operating conditions [2, 3, 4, 5, 6]. This work will demonstrate thrust and pressure gain measurements (although still negative) using an axial air inlet with transverse fuel injection scheme. In addition, the work will discuss the significant source of uncertainties in these measurements with an emphasis on those introduced by the exit choked flow assumption.