Miracle-dz/UniFAR-FTUs huggingface dataset:
Screening of cotton germplasm against cotton leaf curl virus.

Cotton leaf curl virus poses a major threat to cotton productivity in Pakistan. Screening of germplasm to explore resistant source is a basic step towards the solution of this hazardous problem. With this objective genetic material comprising 11060 genotypes of cotton of different research centers was tested at Cotton Research Station, Vehari during 2002 to 2007. During 2002-03, 3694 genotypes were tested on the basis of cotton leaf curl virus disease incidence and 30 (Code No./varieties 124, 141, 170, 185, 218, 244, 252, 338, FVH-153, VH-176, 609, 721, 723, 724, 752, 834, 891, 918, 1018, 106, 111, 114, 115, 141, 156, 160, 175, 178, 183, 253) lines showed no symptoms of this disease. Out of 2792 genotypes screened during 2003-04, 7 (Code No./varieties 124, 170, 244, 252, VH-176, VH-209, 609) were found virus free. During next three years i.e., 2004 to 2006, all the genotypes (4364) showed susceptibility to cotton leaf curl virus disease. Two genotypes (China-1 and China-2) out of 210 tested during 2007 exhibited resistance to cotton leaf curl virus (CLCuV). 119 genotypes were screened on the basis of cotton leaf curl virus intensity during 2002-07, out of which 37 (Code No./varieties 654, 1050, 1411, 1448, 124, 141, 170, 185, 218, 244, 252, 338; 609, 721, 723, 724, 752, 834, 891, 918, 1018; NIBGE-106, NIBGE 111, NIBGE 114, NIBGE115, NIBGE 141, NIBGE156, NIBGE160, NIBGE 175, NIBGE 178, NIBGE 183, NIBGE 253, FVH-153, VH-176, VH-209, China-1, China-2) lines were found virus free. Twenty four lines were tested against Cotton Leaf Curl Virus on the basis of sick plot technique during 2002-07. Among these lines 609 from Cotton Research Station Multan, 3232 from Central Cotton Research Institute Multan, VH156 from Cotton Research Station Vehari, China-14 from Nanjing Agri.University China showed minimum disease incidence 0.8%, 7.6%, 14.75% and 23.5%, respectively. The results of recent research demonstrated that it is possible to explore resistant material from germplasm through screening on the basis of incidence and intensity. The same can be utilized in the breeding programme for evolving CLCuV tolerant/resistance verities of cotton.
OSIRIS-REx Encounters Earth: Signatures of a Habitable World

Balram-Knutson, C.A. Bennett, B.J. Bos, C. Drouet d’Aubigny, P.R. Christensen, E.C.A. Church, D.N. DellaGiustina, H.L. Enos, D.R. Golish, V.E. Hamilton, C.W. Hergenrother, E.S. Howell, J.N. Kidd Jr., M.C. Nolan, D.C. Reuter, B. Rizk, A.A. Simon, and the OSIRIS-REx Team. Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ, USA (lauretta@lpl.arizona.edu). NASA Goddard Space Flight Center, Greenbelt, MD, USA, Arizona State University, Tempe, AZ, USA. Lockheed Martin Space, Littleton, CO, USA. Southwest Research Institute, Boulder, CO, USA. Email: lauretta@lpl.arizona. edu
Batch cultivation of bacterial cells in nanoliter reactor array

We have developed a microfluidic reactor array enabling systematic assessment of bacterial cells in a batch culture condition. This system enables creating a series of different growth conditions by preserving different growth factors inside nanoliter reactors and cultivating bacterial cells inside the reactors. From a single on-chip experiment, we determined the effects of carbon sources on bacterial phenotypes, i.e. the pattern of growth curves with Escherichia coli K-12. We demonstrated the systematic assessment of inhibition effect of antibiotics on the growth of Pseudomonas aeruginosa. The present system could be used for systematic phenotypic study of different types of bacterial cells.
Mathematical modeling of some medium constituents and its impact on the production of vitamin B12 and folic acid by Klebsiella pneumoniae under solid state fermentation

The present investigation involved testing the effect of different carbon sources (glucose, sucrose and starch) as well as different nitrogen sources (peptone, yeast extract and urea) on the production of vitamin B12 using Klebsiella pneumonia grown on mixture of agriculture wastes (wheat straw and rice bran). The results show that glucose was the best carbon source compared to the other di- and polysaccharides used. The best vitamin B12 output (63.87 µg/L) was obtained at 3 g/L glucose. On the other hand, peptone appeared to be the most suitable nitrogen, since it gave (57.8 µg/L) of B12 compared to the other nitrogen sources used. Statistical analysis for the obtained results had been carried out and the data showed that glucose and peptone additions were highly significant compared to the other sources under investigation. Key words: Vitamin B12 production, solid state fermentation (SDF), bacteria.
Repliement et production de protéines recombinantes

La production de proteines recombinantes est une biotechnologie qui entre dans une phase de maturite, entrainant ainsi un essor de la production industrielle. Cependant, le processus de conversion systematique de l'information genetique en proteine biologiquement active se heurte au probleme fondamental du repliement cellulaire des proteines : de nombreuses proteines recombinantes ne sont pas produites dans leur etat natif, et s'agregent dans un etat biologiquement inactif. Bien que ce phenomene d'agregation presente certains avantages pratiques, la renaturation in vitro des proteines recombinantes, apres solubilisation des agregats cellulaires, revet toujours un caractere empirique et aleatoire. Aussi est-il preferable d'intervenir en amont en optimisant les conditions d'expression de la proteine, afin de minimiser ce probleme au sein des cellules. Dans ce domaine, l'alternative la plus prometteuse est certainement le developpement des methodes genetiques permettant le criblage a haut debit des proteines correctement repliees dans la cellule.
Wzrost pobudzany eksportem czy eksport stymulowany wzrostem sektora rolnego

The aim of the article is to analyze the interrelationship between the international exchange of agri-food products and the level of the agricultural production in selected EU countries. The study is based on cointegration analysis methodology and employs vector autoregression models (VAR). The relevance of export expansion for the growth of agricultural production differs in individual EU countries. Agricultural production in Poland has a lot to do with the level of the exports, but it is under the influence of its own developmental tendency, as well. The Polish agri-food exports are shaped heavily by their own trend. No interrelationship was detected between agricultural production and agri-food exports in France. On the other hand, exports are influenced by their trend and additionally a strong impact of the level of agricultural production on exports was detected. To conclude, exports support agricultural production in Poland, and the high level of production of the agricultural sector stimulates exports in France. / Synopsis. Celem opracowania jest analiza wspolzalezności miedzy miedzynarodową wymianą produktami rolno-zywnościowymi a poziomem produkcji rolnej w wybranych krajach UE. Badanie oparto na metodologii analizy kointegracyjnej i modelach wektorowej autoregresji (VAR). Znaczenie ekspansji eksportowej dla wzrostu produkcji rolnej jest odmienne w poszczegolnych krajach UE. W Polsce produkcja rolna jest ksztaltowana w znacznej mierze poziomem eksportu, ale pozostaje takze pod wplywem wlasnej tendencji rozwojowej. Polski eksport rolno-spozywczy jest ksztaltowany wlasną tendencją rozwojową. Dla Francji nie wykryto wspolzalezności miedzy produkcją rolną i eksportem rolno-zywnościowym. Z drugiej strony, eksport jest ksztaltowany wlasną tendencją rozwojową i zidentyfikowano zaleznośc miedzy eksportem i produkcją rolną. Podsumowując, w Polsce eksport wspiera produkcje rolną, a we Francji wysoki poziom produkcji sektora rolnego stymuluje eksport.
Manifestations of addictive behaviour among the child players of the Minecraft game from the perspective of quantitativeresearch

Příspěvek se zaměřuje na analýzu projevů online závislostního chování u hráčů populární hry Minecraft, a to pohledem kvantitativního výzkumu realizovaného na přelomu roku 2016 a 2017 na území České republiky. Do výzkumu se zapojilo více než 2 300 hráčů (n = 2 331). Autoři se zaměřují především na projevy nadměrného hraní této hry v oblasti psychické, fyziologické a behaviorální. Klíčová slova: Minecraft, online hraní, kyberšikana, kybergrooming, sexting, závislostní chování, netolismus.
Keywords: Pompano, carnivorous marine fish, nutritional requirements, soybean meal Dietary protein/energy ratios for adult Florida pompano, Trachintous carolinus: feed, growth and nitrogen utilization

Selecting a new fish species with a potential value for aquaculture has essential importance for the future development of the aquaculture industry. In the United States, Florida pompano, Trachinotus carolinus, is among the marine fish species with aquaculture potential that has caught the interest of the industry for being a truly euryhaline species. Research is needed to complete our knowledge of the nutritional requirements of Florida pompano at different ages in order to develop cost-effective and environmentally-friendly diets. With the recent interest in high market-value carnivorous species, cost concerns are extremely important since carnivorous fish require greater amounts of protein and fishmeal represents the primary protein source in feeds formulations. A review of the literature confirms the importance of completing the nutritional requirements for Florida Pompano at different ages in the development of cost-effective and environmentally-friendly diets. Our goal was to examine the nutritional requirements in terms of protein and energy for Florida Pompano close to its typical marketable weight, which is between 400 and 600 g. To date, only the nutritional requirements for juvenile fish weighing up to 45 g have been examined. Since nutritional requirements have been well described to change as a fish grows and develops, it is essential that the requirements for larger Pompano, which consume greater quantities of foods than their smaller counterparts, be elucidated. This is most important for protein and lipid levels as they are the most expensive dietary components.
THE ROLE OF NERVE GROWTH FACTOR DURING CHRONIC INFLAMMATION OF THE DESCENDING COLON IN VIVO: A NOVEL SOURCE FOR NERVE GROWTH FACTOR

ii Co-Authorship iii Acknowledgements iv List of Figures vi List of Tables vii List of Abbreviations viii Chapter 1 General Introduction 1 1.1 The seminal discovery of nerve growth factor 1 1.2 Nerve growth factor 2 1.3 TrkA: The high-affinity NGF receptor 4 1.4 The p75 neurotrophin receptor 6 1.5 The reception of NGF 11 1.6 Dogiel type II myenteric neurons 12 1.7 Hypothesis 15 Chapter OVEREXPRESSION OF NERVE GROWTH FACTOR BY MURINE SMOOTH MUSCLE CELLS: ROLE OF P75 NEUROTROPHIN RECEPTOR ON SYMPATHETIC AND SENSORY SPROUTING 16 2.1 ABSTRACT 17 2.2 INTRODUCTION 18 2.3 MATERIALS AND METHODS 22 2.4 RESULTS 33 2.5 DISCUSSION 42 Chapter 3 DOGIEL II MYENTERIC NEURONS IN THE MOUSE COLON DISPLAY NERVE GROWTH FACTOR PROMOTER ACTIVITY 67 3.1 ABSTRACT 68 3.2 INTRODUCTION 69 3.3 MATERIALS AND METHODS 71 3.4 RESULTS 80 3.5 DISCUSSION 85 Chapter 4 GENERAL DISCUSSION 98 REFERENCES 107
Feature Extraction Method from Electronic Health Records in Russia

The medical language is the basis of the electronic medical records (EHR), and up to 70 percent of the information in these records were writing in natural language, in the free text part [1]. The last few years have seen a surge in the number of accurate, fast, publicly available name entity recognition (NER) parsers [2,3]. At the same time, the use of NER parsing in natural language processing (NLP) applications has increased. It can be difficult for a non-expert to select a good “off-the-shelf” parser. We present a method of using statistical NER parsers on a medical corpus of Russian. We developed a new tool that gives a convenient way to extract NER from unstructured medical documents.
Realization of Cascaded H-Bridge Multilevel Inverter Based Grid Integrated Solar Energy System With Band Stop Generalized Integral Control

The high power grid integrated solar energy system (GISES) prefers multilevel inverters for reduced switching losses and lower harmonics in the injected current. The integration of solar PV array with multilevel inverters (MIs) requires a proper selection of multioutput dc–dc converters. Moreover, the performance of two-stage GISES with isolated multioutput dc–dc converters and dc–ac multilevel inverters are less investigated in the literature. In this article, a cascaded H-bridge multilevel inverter with isolated multiple-output zeta converter is used. It exhibits reduced switching stresses and improved efficiency, concerning to multiple dc–dc converters fed MI. The maximum power point tracking method, based on the firefly algorithm, is implemented on the isolated multiple output zeta converter to ensure maximum power extraction at adverse irradiation conditions. The power quality improvement and active power exchange through a band stop generalized integral control, and the grid synchronization is achieved through an enhanced phase-locked loop method. The proposed system is designed and simulated in MATLAB/Simulink, and the results validate the theoretical claims. The performance of the GISES is verified using an experimental prototype developed with the help of a dSPACE Micro Lab Box and a solar PV simulator.
Towards reducing the time needed for load testing

The performance of large‐scale systems must be thoroughly tested under various levels of workload, as load‐related issues can have a disastrous impact on the system. However, load testing often requires a large amount of time, running from hours to even days. In our prior work, we reduced the execution time of a load test by detecting repetitiveness in individual performance metric values, such as CPU utilization, that are observed during the test. However, as we explain in this paper, disregarding combinations of performance metrics may miss important information about the load‐related behavior of a system. In this paper we revisit our prior approach, by proposing an approach that reduces the execution time of a load test by detecting whether a test no longer exercises new combinations of the observed performance metrics. We study three open source systems, in which we use our new and prior approaches to reduce the execution time of a 24‐hour load test. We show that our new approach is capable of reducing the execution time of the test to less than 8.5 hours, while preserving a coverage of at least 95% of the combinations that are observed between the performance metrics during the 24‐hour tests.
SGAxe: How SGX Fails in Practice

—Intel’s Software Guard Extensions (SGX) promises an isolated execution environment, protected from all software running on the machine. A signiﬁcant limitation of SGX is its lack of protection against side-channel attacks. In particular, recent works have shown that transient-execution attacks can leak arbitrary data from SGX, breaching SGX’s conﬁdentiality. However, less work has been done on the implications of such attacks on the SGX ecosystems. In this work we start from CacheOut, a recent conﬁdentiality attack on SGX, which allows the retrieval of an enclave’s memory contents. We show how CacheOut can be leveraged to compromise the conﬁdentiality and the integrity of a victim enclave’s long-term storage. By using the extended attack against the Intel-provided and signed architectural SGX enclaves, we retrieve the secret attestation key used for cryptographically proving the genuinity of enclaves over the network, allowing us to pass fake enclaves as genuine. Finally, we analyze the impact of our attack on two proposed SGX applications, the Signal communication app and Town Crier, an SGX-based blockchain application.
The Zebra Mussel (Dreissena polymorpha Pallas) Invades Ireland: Human Mediated Vectors and the Potential for Rapid Intranational Dispersal

Abstract:In this account we demonstrate that different vessel classes and different types of boat movement are important in determining the role of pleasure craft as a vector for transmission of zebra mussels. Vessels with zebra mussels on their hulls have been found in areas where zebra mussels are not known to be established. The main concern is the overland transport of boats to lakes at more elevated levels within infested catchments and to other river systems. Large boats that are heavily fouled pose the highest risk. However, these are moved infrequently compared with angling boats, which are moved from fly hatch to fly hatch. Up to three size classes of zebra mussels with densities greater than 1000m⁻² have been recovered from the hulls of several different classes of vessel. Such numbers are probably sufficient to form new populations, following spawning in areas where zebra mussels did not previously exist. This may have happened in several lakes in Ireland from 1996-8. Vessels most likely to acquire large numbers of zebra mussels are those that remain idle for long periods of time. This would appear to be the case for barges, canal boats, private cruisers and lake boats. An assessment of the vectors that disperse zebra mussels allows efforts to slow down intranational spread to be focussed.
AOP Title Binding of antagonist to N-methyl-D-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities Short name: Binding of antagonist to NMDARs impairs cognition

It is well documented and accepted that learning and memory processes rely on physiological functioning of the glutamate receptor N-methyl-D-aspartate (NMDAR). Both animal and human studies investigating NMDA itself, experiments with NMDAR antagonists and mutant mice lacking NMDAR subunits strongly support this statement (Rezvani, 2006). Activation of NMDARs results in long-term potentiation (LTP), which is related to increased synaptic strength, plasticity and memory formation in the hippocampus (Johnston et al., 2009). LTP induced by activation of NMDA receptors has been found to be elevated in the developing rodent brain compared to the mature brain, partially due to 'developmental switch' of the NMDAR 2A and 2B subunits (Johnston et al., 2009). Activation of the NMDAR also enhances brain derived neurotrophic factor (BDNF) release, which promotes neuronal survival, differentiation and synaptogenesis (Tyler et al., 2002; Johnston et al., 2009). Consequently, the blockage of NMDAR by chemical substances during synaptogenesis disrupts neuronal network formation resulting in the impairment of learning and memory processes (Toscano and Guilarte, 2005). This AOP is relevant to developmental neurotoxicity (DNT). The molecular initiating event (MIE) is described as the binding of antagonist to NMDAR in neurons during synaptogenesis (development) in hippocampus (one of the critical brain structures for learning and memory formation). Chemicals that block NMDAR are known developmental neurotoxicants such as lead (Pb2+), toluene and ethanol. Additionally there are some specific pharmaceuticals such as MK-801, ketamine, dextromethorphan, pethidine, methadone, dextropropoxyphene, tramadol and ketobemidone that are selective antagonists of NMDAR too.
The relative success of strains of Trifolium subterraneum L. in binary mixtures under field conditions

Mixtures of Dwalganup/Northam A, Dwalganup/Uniwager, Dwalganup/Daliak, Yarloop/Daliak and Yarloop/Seaton Park were grazed over a 6-year period. An additional mixture (Yarloop/Woogenellup) was abandoned after 2 years of grazing because of contamination by unsown strains. The principal finding with respect to the initial 50/50 mixtures was that Uniwager differed from the other new strains Northam A, Daliak and Seaton Park in that it was not successful. When grown with the three latter strains the proportion of Dwalganup and Yarloop, measured during the growing season, fell to about 10%. This result was considered very promising in connexion with the 'clover disease' problem which occurs on pastures dominated by Dwalganup and Yarloop. The factors influencing success and failure are discussed briefly, and the importance of the seedling establishment phase is emphasized.
Departament de Sanitat i d'Anatomia Animals Universitat Autonoma de Barcelona

Immunization of piglets with two different European-type modified live vaccines against porcine reproductive and respiratory syndrome (PRRS) virus produced different outcomes. After vaccination, pigs became viremic (42 days), neutralizing antibodies did not develop, and frequencies of virus-specific gamma-interferon-secreting cells (IFN-γ-SC) were low. Levels of interleukin-10 (IL-10) produced by peripheral blood mononuclear cells (PBMC) seemed to inversely correlate with interferon-gamma responses. After a challenge with a virulent Spanish strain, one vaccine (V3) protected piglets against viremia while the other (V1) did not. The vaccine V3 induced the highest IFN-γ-SC frequencies. IL-2, IL-4 or transforming growth factor-beta responses were not detected at any time for neither of the vaccines. In contrast, haptoglobin rose in sera of viremic pigs after the challenge. These results indicated a strong involvement of IFN-γ, and maybe IL-10, in the development of immunity against PRRS virus. © 2006 Elsevier Inc. All rights reserved.
On Some Important Characteristics of Radio Emission from Air Showers in the Ultra High Energy Domain

The observation of radio-frequency (RF) pulses associated with extensive air showers (EAS) initiated by cosmic rays has a long history. After the experimental proof for the existence of the radio pulses was made by Jelley et al., a number of groups started working on the theoretical interpretation of the emission process. For frequency f > 10 MHz, Falcke and Gorham concluded that radio emission from extensive air showers is dominated by "geosynchrotron radiation" emitted by secondary shower electrons and positrons being deflected in the earth’s magnetic field. The LOPES experiment now has detected the radio emission from cosmic rays and confirmed the geosynchrotron effect for EAS in the frequency f > 10 MHz. In this paper, RE model of EAS for Ultra high energy domain is put forward on the basis of transition radiation (TR) phenomenon for frequency f < 10 MHz. The present investigation for frequency f < 10 MHz, reveals that this frequency domain has very high potential to contribute to the field of radio detection of ultra high energy particle due to: higher field strengths for f < 10 MHz compared to those for f > 10 MHz & significant variation of field strengths with frequency, zenith angle & shower size for f < 10 MHz. For EAS, in the energy range 10 to 10eV, the production mechanism of RE has been established to be TR for f < 10MHz. For Giant Air Shower (GAS) also, TR model developed in the present work for f < 10 MHz can be employed for analysis of experimental observations. AMS Subject Classification: