Miracle-dz/UniFAR-FTUs huggingface dataset:
Mesiodens - case report

Mesiodens is supernumerary tooth which is situated between the central incisors. The most frequent type of supernumerary tooth is a mesiodens. Supernumerary teeth may also disturb the teeth eruption and cause several complications, such as ectopic eruption and midline diastema. A 13 year-old girl (VA), with mesiodens in the upper jaw was presented in this article. She has esthetics, diastema mediana and ectopic position of the left central incisor was present. Orthopantomogram investigations revealed the presences of excessive teeth, in the upper jaw. According to the orthopantomogram’s and clinical findings, the patient was sent at the Department of Oral Surgery for the extraction of the mesiodens. Early and regular dental visits will help to diagnose and avoid problems that mesiodens can cause. Extraction of the mesiodens in the early mixed dentition was recommended, to decrease the risk of clinical complications, lighter spontaneous eruption of adjacent teeth and reduced need for orthodontic treatment after surgery. DOI: http://dx.doi. org/10.5281/zenodo.3252560
The influence of socio-economic variables on the occurrence of anxiety and depression
disorders in women with the female genital tract tumours

Objectives.The aim of the study was to examine the level of anxiety and depression in female patients with genital tract tumours depending on socio-economic conditions, including: education, type of work performed, financial and housing situation. Materials and Method.The research was conducted in the Gynaecological Oncology Clinic,at the Franciszek Łukaszczyk Oncology Centre in Bydgoszcz. The study was carried out on 73 patients with female genital tract tumours qualified for surgical treatment. The Hospital Anxiety and Depression Scale (HADS) and an own personal questionnaire were used in the study. P≤ 0.05 was considered statistically significant. Results.Analysis of research showed that socio-economic conditions influenced the occurrence of anxiety and depression disorders. The unemployed patients displayed a higher level of anxiety and depression compared to a group of patients performing intellectual and mixed work (mental and physical). In the examined group, the financial and housing situation also affects the level of anxiety and depression. Patients presenting a good financial situation had a statistically significantly lower level of anxiety and depression compared to patients with a medium financial situation. Analyzing the housing situation – patients with a very good housing situation had a lower level of anxiety and depression than patients with a good housing situation. There was no relationship between education and the occurrence of anxiety and depression in the study group. Conclusions.Healthcare personnel should pay particular attention to unemployed patients whose financial and housing situation is unsatisfactory. This is a higher-risk group of patients who have a more significant risk of occurrence or intensification of depression and anxiety disorders.
A Single Center Experience for a Feasibility of Totally Laparoscopic Living Donor Right Hepatectomy

Liver transplantation from living donors is a potential treatment for end-stage liver disease. With advancement of laparoscopic techniques and development of surgical devices, laparoscopic liver resection is becoming increasingly popular because of the minimal invasiveness and excellent cosmetic outcomes. However, owing to technical difficulties, pure laparoscopic donor hepatectomy develops relatively slowly. Pure laparoscopic donor hepatectomy has the great advantage of reducing morbidity, minimizing tissue trauma, and improving postoperative pain and cosmetic outcome. However, pure laparoscopic donor hepatectomy may result in a longer operation time and increased risk of bile duct injury. With continuous technical development and building experience for standardization of the technique, pure laparoscopic donor hepatectomy is expected to be further expanded in the future.
Bistatic Radar Without Trans m itted Signa I-Covert Altimetry Concept

A technique for performing altimetric functions (and possibly very-low-resolution imaging radar) without the transmission of a signal is suggested. The system could benefit an invasive aerospace platform that needs to remain totally electronically silent. The concept uses naturally occurring galactic noise as the illumination signal. A rapid and low-cost processor is also suggested. The results developed are also useful for the particular case of low probability of intercept (LPI) radar in which the transmitter emits a broadband Gaussian-like signal and the receivers cannot locally generate the transmitted reference. Another derivation of the arcsine law is provided along with a measure of its efficiency compared with an optimal receiver. >
FoodMood: Measuring Global Food Sentiment One Tweet at a Time

Do Happy Meals really make us happy? Do salads make us blue? Is cake our comfort? FoodMood is an interactive data visualisation project that gives citizens a rare opportunity to engage and reflect, acknowledge, and understand the connection between emotion, obesity and food. The project explores the opportunities presented by the data-sharing world of today’s cities using global English-language tweets about food coupled with sentiment analysis. It aims to gain a better understanding of global food consumption patterns and its impact on the daily emotional well-being of people against the backdrop of country data such as Gross Domestic Product (GDP) and obesity levels. A key finding is that tweets can be used to find a relationship between certain foods, food sentiment and obesity levels in countries. Overall FoodMood shows a majority positive sentiment towards food. Other findings, although constantly evolving, indicate trends such as: globally meat enjoys a high sentiment rating and is often tweeted about; fast-food companies dominate the food consumption landscapes of most countries’ tweets although not all of them enjoy equal sentiment ratings across countries. Ultimately, FoodMood reveals a hidden layer of meaningful digital, social, and cultural data that provide a basis for further analysis.
A CHRONOLOGICAL LIST OF REFERENCES ON SWITCHED CAPACITOR CIRCUITS

A chronological list of 440 references on switched capacitor circuits is compiled. Such circuits have cut the cost of filters and signal processing devices for telecommunications, speech and consumer products because they can be easily integrated on a chip. The bibliography shows the explosion of interest since 1977 by IC designers, CAD developers and circuit and filter theorists and practitioners alike.
MACHINE TRANSLATION USING MUTIPLEXED PDT FOR CHATTING SLANG

This article extends my work, a pioneering step in designing Bi-Gram based decoder for SMS Lingo. SMS Lingo is a language used by young generation for instant messaging for chatting on social networking websites called chatting slang. Such terms often originate with the purpose of saving keystrokes. In last few decades, a significant increment in both the computational power and storage capacity of computers, have made possible for Statistical Machine Translation (SMT) to become a concrete and realistic tool. But still it demands for larger storage capacity. My past work employs Bi-Gram Back-off Language Model (LM) with a SMT decoder through which a sentence written with short forms in an SMS is translated into long form sentence using non-multiplexed Probability Distribution Tables (PDT). Here, in this article the same is proposed using multiplexed PDT (a single PDT) for Uni-Gram and Bi-Gram, so smaller memory requirements. Use of N-Gram LM in chatting slang with multiplexed PDT, is the objective behind this work. As this application is meant for small devices like mobile phones we can prove this approach a memory saver.
Platelet-To-Lymphocyte Ratio as a Predictor of No-Reflow after Primary Percutaneous Coronary Intervention in Patients with ST Elevation Myocardial Infarction: A Systematic Review and Meta-Analysis

Introduction: No-reflow increases the complications and mortality rate of primary percutaneous coronary intervention (PCI). Therefore, it is important to identify patients at a higher risk of developing no-reflow. This study aimed to systematically review the prognostic value of the platelet-to-lymphocyte ratio (PLR) to predict no-reflow. Materials and Methods: The databases, such as Pubmed, EMBASE, and Web of Knowledge were searched for the relevant studies. Two authors independently performed data extraction and quality assessment of the included studies. In this meta-analysis, sensitivity and specificity of PLR, as well as the pooled odds ratio were calculated to predict no-reflow and compared with the pooled means of PLR in no-reflow and reflow groups. Results: According to the results obtained from six out of eight studies in this systematic review, there was a significant association between PLR and no-reflow. Moreover, a pooled six-fold increase of no-reflow risk was observed in the high PLR group. Pooled sensitivity and specificity of PLR to predict no-reflow was 65% (CI95%: 61%-69%) and 77% (CI95%: 76%-79%), respectively. The mean pooled of PLR in the no-reflow group was significantly 65.2 (CI95%: 26.7-103.8) units higher than that in the reflow group. Conclusions: The PLR is a significant predictor of no-reflow in STEMI patients subjected to primary PCI which can be used alone or in combination with other markers to identify patients at higher risk of developing no-reflow.
Radícula de malte na alimentação de suínos em crescimento e terminação

Em 1983, na Cooperativa Agraria Ltda, municipio de Guarapuava, PR, realizou-se um experimento com objetivo de determinar o melhor nivel de inclusao de radicula de malte em racoes para suinos em crescimento e terminacao, com peso vivo inicial de 24,79 ± 0,14 kg e final de 90,28 ± 1,63 kg. Os tratamentos, dispostos em delineamento inteiramente casualizado, foram representados por niveis de inclusao de 0%, 7%, 14%, 21% e 28% de radicula de malte, com quatro repeticoes por tratamento e seis animais por unidade experimental. Considerando o periodo experimental total, obteve-se um efeito linear (P < 0,05) para o ganho de peso diario medio (GPDM = 757,8000 - 5,7214 X; R 2 = 0,52) e conversao alimentar (CA = 2,9610 + 0,0255 X; R 2 = 0,80). Regressoes lineares decrescentes (P < 0,05) foram obtidas para as variaveis: rendimento de carcaca fria, peso de pernil, materia seca digestivel, retencao de nitrogenio e coeficiente de digestibilidade da proteina bruta. Regressoes cubicas (P <0,05) foram calculadas para as energias disgestivel e metabolizavel. Constatou-se que, economicamente, a radicula de malte nao deve ser utilizada para suinos, quando as condicoes existentes forem semelhantes as deste experimento.
Using Spreadsheets to Teach Data Encryption Techniques

There are a variety of reasons why understanding encryption technology is likely to become increasingly important in the future, and therefore why accounting courses are likely to include encryption materials in future curricula. This paper discusses five encryption techniques: transposition ciphers, cyclic substitution ciphers, Vigenere ciphers, exclusive OR ciphers, and permutation ciphers. Accompanying these discussions are explanations of how instructors can demonstrate these techniques with spreadsheet models. The author's experiences with such models in classroom use have been uniformly positive.
Generic Approach for Goal Driven Software Requirement Risk Management

An analysis of many software program assignments in between 2011, as well as 2014, shows an interesting pattern. Author identified areas which may lead to project failure which are weak requirement analysis and management, weak cost calculating, weak handling of requirement change requests, weak milestone monitoring and requirement gold plating habit. By comparison, prosperous local software program assignments tended to be much better than onsite software development and management. Maybe the most interesting part of most of these many problem areas can be that each is regarding project managing instead of using technical personnel. We focused over the impact of software requirement change requests and requirement gold plating while dealing with onsite project assignments. Author also evaluated new model to avoid global software engineering requirement failure, which in turn curtails the estimated time and budget with client satisfaction. In this paper, Author discuss the ideas that support requirements reflection as a means to articulate some of the outstanding research challenges. General Terms Software Engineering
RNAi/gene therapy combined approach as therapeutic strategy for Charcot-Marie-Tooth 2A (S58.005)

Objective: To investigate a novel therapeutic approach for Charchot-Marie-Tooth disease type 2A (CMT2A) using RNAi/gene therapy combination. Background: CMT2A is a rare inherited axonal peripheral neuropathy caused by mutations in the mitofusin 2 (MFN2) gene and characterized by progressive distal muscle weakness, atrophy, sensory loss, and normal or near-normal nerve conduction velocities. MFN2 mutations have been characterized and numerous mechanisms proposed to unravel CMT2A pathophysiology; however, no cure for this devastating disease is available. Thus, it is crucial to identify a treatment to cure or at least mitigate CMT2A progression. Design/Methods: Our proposed approach combined RNA interference (RNAi) with gene therapy as therapeutic strategy for CMT2A. In induced pluripotent stem cells (iPSCs) obtained from CMT2A patients we targeted the MFN2 mutant allele with specific short hairpin RNAs (shRNAs) and simultaneously introduced a mutagenized MFN2 gene able to be resistant to shRNA activity and still encoding the native protein. We then differentiated iPSCs into spinal motor neurons (MNs) and analyzed the sub-cellular parameters we previously found to be altered in CMT2A in vitro model (Rizzo et al., 2016) were evaluated to assess the impact of our therapy. Results: We successfully silenced endogenous MFN2 gene and restored functional MFN2 protein level in CMT2A cells without altering iPSC pluripotency. In addition, MNs differentiated from both treated and untreated CMT2A iPSCs showed typical MN morphology and expressed the main MN markers. Qualitative and quantitative alterations characteristic of CMT2A disease (Rizzo et al., 2016) were restored after our therapy in CMT2A MNs. Specifically, we observed an increase in mitochondria number, an improvement of mitochondrial axonal transport, re-established sensitivity to apoptosis and reduction of authophagy/mytophagy. Conclusions: Overall, our results led to a significant level of rescue in CMT2A MNs, suggesting RNAi/gene therapy combined approach as a promising therapeutic strategy for CMT2A. Disclosure: Dr. Rizzo has nothing to disclose. Dr. Bono has nothing to disclose. Dr. Salani has nothing to disclose. Dr. Bordoni has nothing to disclose. Dr. Melzi has nothing to disclose. Dr. Ruepp has nothing to disclose. Dr. Pagliarani has nothing to disclose. Dr. Barbullushi has nothing to disclose. Dr. Abati has nothing to disclose. Dr. Cordiglieri has nothing to disclose. Dr. Bresolin has nothing to disclose. Dr. Comi has nothing to disclose. Dr. Nizzardo has nothing to disclose. Dr. Corti has nothing to disclose.
Efficacy of interventional therapy and effect on inflammatory factors in patients with gastric cancer after chemotherapy

The clinical effect of interventional therapy on gastric cancer after chemotherapy and effect on inflammatory factors in peripheral blood serum of patients were investigated. A retrospective analysis of 429 patients with gastric cancer treated in Xiangyang No. 1 People's Hospital, Hubei University of Medicine from July 2008 to December 2014 was performed. Among them, 220 patients received interventional therapy after chemotherapy as the experimental group, and 209 patients received conventional therapy as the control group. Serum carcinoembryonic antigen (CEA), tumor markers CA19-9, interleukin-6 (IL-6), interleukin-8 (IL-8) and interleukin-10 (IL-10) levels were measured before and after chemotherapy. The correlation between the concentration of CEA and CA19-9 before and after treatment and the levels of IL-6, IL-8 and IL-10 were analyzed in the experimental group, and all patients were followed up for 3 years. There were no significant differences in CEA, CA19-9, IL-6, IL-8 and IL-10 between the two groups before chemotherapy (P>0.05). After treatment, the concentrations of CEA, CA19-9, IL-6, IL-8 and IL-10 in the experimental group were significantly lower than those in the control group before and after treatment (P<0.05). The clinical efficacy and adverse reactions of the experimental group were significantly better than those in the control group (P<0.05). Pearson's correlation analysis showed that the concentrations of CEA and CA19-9 in the serum of the experimental group before and after treatment were positively correlated with the levels of IL-6, IL-8 and IL-10 (P<0.05). The 3-year overall survival rate of the study group was significantly higher than that of the control group (P<0.05). Cox regression analysis showed that age, Borrmann classification, degree of differentiation, and history of Helicobacter pylori infection were independent prognostic factors for patients with gastric cancer. Compared with traditional treatment, interventional therapy can greatly improve the recovery of gastric cancer patients after chemotherapy, reduce the occurrence of complications and inflammation, and improve the survival rate of patients.
Understanding the explosive divergence of the FTF algorithm

Along with its many desirable properties the fast transversal filter (FTF) algorithm suffers from explosive divergence. This type of divergence occurs when the algorithm is seemingly performing its operations normally, producing usable solutions, when the algorithm appears to suddenly produce extremely large errors and an obviously useless solution. Although it is known that a loss of backward consistency is the cause for the resultant perturbations, i.e., a violation to interrelationships between update parameters are not explicitly enforced by the update equations, it is not known why the algorithm suffers explosive divergence rather than a divergence that grows as a continuous function over time. Algorithms have been proposed to circumvent this problem but it remains to be shown through theoretical justification whether these algorithms have remedied the problem or only put it off to some later iteration. Here, we provide a rationale to explain the explosive character of divergence that is inherent to the manner in which the FTF algorithm is derived.
Psychosocial stress and telomere regulation

Telomeres, the repetitive nucleoprotein regions at chromosome ends, are hallmarks of biological aging. Deficiencies in the network of proteins and nucleic acids which govern telomere regulation result in their gradual erosion over time, and shorter telomere length is associated with chronic disease as well as all-cause mortality. Telomeres are also indicative of cumulative stress experienced across the lifespan. This chapter summarizes empirical evidence for the impact of lifelong psychosocial stress, lifestyle behaviors, and chronic diseases on telomere biology. This biological embedding of experiences involves complex interactions with cellular processes regulating telomere length. Before describing such interactions, the chapter chronicles intrinsic regulation of telomeres by enzymatic, RNA, and epigenetic mechanisms. It then considers the stress-related mechanisms implicated in telomere regulation, including neuroendocrine systems, immuno-inflammation, oxidative stress, and mitochondrial respiration. A full understanding of these processes can promote better clinical treatments and intervention efforts to reverse the damaging effect of stress on telomeres.
A unified formula for K-terminal reliability analysis in ring networks

A formula that uses K-minimal Eulerian circuits and the inclusion-exclusion property to efficiently compute K-terminal reliability R/sub K/(G) for ring networks is presented. This formula is applied to three fiber distributed data interface (FDDI) ring network topologies, and it is shown that the time complexity of computing each K-terminal reliability expression is polynomially bounded. The applicability of the authors' approach is illustrated by deriving a closed-form expression of R/sub K/(G) for the FDDI double-ring topology in terms of the failure probabilities of links, network ports, and station common units. <<ETX>>
Prosthetic Dentistry Possibilities In Patients With Cleft Deformities Of The Palate and Alveolar Ridge

A 56 year old man presented with one-sided cleft palate, affecting alveolar ridge in the upper left canine region. Patient was unable to eat and drink without having the food fall out through his mouths opening into his nose. During first visit, patient underwent x-ray analysis to identify how deeply the bone damage has affected his maxilla. It revealed deep bone penetration, connecting the base of the nose with the mouth. We suggested one of the most effective methods for treating these types of cases – a removable partial denture, which was made to work as an obturator at the same time, closing the space, which causes difficulties to the patient. This case report represents a rare presentation and treatment of cleft palate by using removable partial dentures (RPDs) to close the gap, connecting the patient’s mouth with the nose structures.