Miracle-dz/UniFAR-FTUs huggingface dataset:
Developing and Validating a Scale to Assess Organizational Behavior Foundations

This study was implemented to develop and validate a scale to assess organizational behavior foundations. Meanwhile, considering Hinkin’s (1995) scale development stages and using Robbins and Judge’s (2008-2009) framework, a survey was made containing 3 dimensions (individual, group and organizational), and 23 fundamental factors. The surveys were implemented among 250 male and female staff of an organization selected using simple stratified random sampling method. To develop the scale, first we identified a potential set of items for the constructs; next we assessed the psychometric properties of the scale by examining its components’ relationship, using item-total correlations analysis. Results indicated that the scale was well-constructed, and had high reliability. Confirmatory factor analysis also was used to assess the measurement model and to infer the existence of construct’s validity. Results demonstrated that the scale contains relatively good validity to explain the effects of organizational behavior foundations on staff behavior. DOI: 10.5901/mjss.2016. v7n6p61
Novel High Speed Vedic Mathematics Multiplier using Compressors

With the advent of new technology in the fields of VLSI and communication, there is also an ever growing demand for high speed processing and low area design. It is also a well known fact that the multiplier unit forms an integral part of processor design. Due to this regard, high speed multiplier architectures become the need of the day. In this paper, we introduce a novel architecture to perform high speed multiplication using ancient Vedic math’s techniques. A new high speed approach utilizing 4:2 compressors and novel 7:2 compressors for addition has also been incorporated in the same and has been explored. Upon comparison, the compressor based multiplier introduced in this paper, is almost two times faster than the popular methods of multiplication. With regards to area, a 1% reduction is seen. The design and experiments were carried out on a Xilinx Spartan 3e series of FPGA and the timing and area of the design, on the same have been calculated.
An Overview of Cancer Chemopreventive Potential and Safety of Proanthocyanidins

Cancer is a major public health problem worldwide. Over two-thirds of cancer-related deaths could most probably be prevented through lifestyle modification, particularly through dietary means. Proanthocyanidins (PAs), the most abundant polyphenolic substances after lignin in the plant kingdom, have been widely investigated for their chemopreventive potential. The PAs literature has, however, been mostly concerned with positive cardiovascular activities, and recent reviews about cancer chemoprevention are scarce. The present review highlights a series of in vitro and in vivo studies indicating (1) that PAs can act as anticarcinogenic agents through their antioxidant, apoptosis-inducing, immuno-modulating, and/or enzyme modulating properties, effects on epigenetics; and (2) that PAs could be particularly safe dietary compounds. These convergent data encourage further research to better understand the many aspects of cancer chemoprevention by PAs.
Tibolone : A Selective Tissue Estrogenic Activity Regulator

Tibolone is a STEAR (Selective tissue estrogenic activity regulator) (1). It is a synthetic steroid with tissue selectivity that has progestogenic, some androgenic as well as estrogenic effects. It has been used as an alternative to estrogen replacement therapy in several European countries for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and treatment of climacteric symptoms. Mechanism of action (2) : Tibolone itself has no biological activity; its effects are the results of the activity of its metabolites on various tissues. After administration, tibolone is quickly metabolized into 3a-hydroxytibolone (3 s OH-tibolone) and 3 s-OH-tibolone compounds, which are also present in an inactive, sulfated form. A third compound, the ? 4isomer, is formed from tibolone directly or from the 3 s -OH-metabolites. Tibolone has estrogenic effects on bone and vaginal tissue. In endometrial tissue the ? 4-isomer functions as a progestagen, whereas in the brain and liver it has androgenic effects. In breast tissue, the main actions of tibolone are strong inhibition of sulfatase activity and weak inhibition of 17 a -hydroxysteroid dehydrogenase activity, which result in blocking the conversion of estrone sulfate to E2. Tibolone actions are as follows :
Análisis de la asociación entre alelos HLA clase II y leucemia en población mestiza venezolana. Potenciales implicaciones patogénicas

De este trabajo traslacional de investigacion de la asociacion de alelo HLA clase II con LLA y LMC en poblacion mestiza venezolana se concluye que: Existen asociaciones positivas entre los alelos DQB1*04*, dpa1*01:07, *01:08, *01:06 con la LLA y los alelos DRB1*14, DPA1*02:01 con la LMC. Las asociaciones alelicas de HLA clase II encontradas en la LLA y LMC son diferentes. La frecuencia alelica del DRB1*13 en la poblacion venezolana no inmigrante reciente demuestra un elevado nivel de mestizaje con presencia de genes caucasicos, afrodescendiente e indigenas. El patron de positividad de respuesta serologica IgM a adenovirus en pacientes con LLA es similar al encontrado en los controles sanos y, por el contrario fue negativo en la mayoria de los enfermos con LMC. La utilizacion de alelos de HLA DRB*13 y 14 relacionados con la respuesta a adenovirus es diferente en pacientes con LMC y en la poblacion control. El patron de respuesta del compartimento linfocitario T a antigenos del adenovirus es distinta en pacientes con LMC y controles. Tomados en conjunto, estos resultados indican, que existen factores geneticos del sistema HLA asociados a la LLA y LMC. Ademas, el patron diferente de utilizacion de estos genes y la respuesta al adenovirus, sugieren que los mecanismos celulares implicados en la patogenia de ambas entidades, son diferentes.
New fully differential instrumental chain for Hall sensor signal conditioning integrated in standard 0.35 μm CMOS process

This paper describes a new integrated fully differential analogue instrumental chain dedicated to magnetic field measurement. This chain features a silicon Horizontal Hall Device, high CMRR low thermal noise instrumentation amplifiers as well as a modulation — demodulation system based on the chopper stabilized technique operated at 100 kHz. This allows offset and 1/f noise cancellation by multistage high-pass filtering. The system achieves 10 μΤ resolution (experimental) over a 3.6 kHz bandwidth by applying 100 kHz spinning current to the Hall Device.
Δ‐Aminolevulinatedehydrase: synteny with ABO‐AK1‐ORM (and assignment to chromosome 9)

A material comprising 846 normal families from the Copenhagen area (fam. no. 604–1505) was tested for δ‐aminolevulinatedehydrogenase. Among the 1697 unrelated individuals (parents), the gene frequencies were 0.9378 for ALADH*1 and 0.0622 for ALADH*2. The distribution of phenotypes and the segregation ratios did not deviate significantly from the expected values. Linkage analysis was carried out for markers on chromosome 9, following up a hint of ALADH‐ORM linkage in part of the material. This was confirmed, and the most likely sequence, as judged from male θ values, was found to be ABO‐AK1 ‐ALADH‐ORM. The θand ž values were as follows; ABO‐AK1 (θ=0.13, ž= 6.27), ABO‐ALADH (θ=0.21, ž= 5.38), ABO‐ORM (θ=0.27, ž=5.06), AK1‐ORM (θ=0.17, ž= 1.63), ALADH‐ORM (θ=0.13, ž= 7.05) and AK1‐ALADH (θ=0.11, ž= 2.45).
Effect of Captopril, Losartan, and Bradykinin on Early Steps of Insulin Action

Insulin initiates its metabolic and growth-promoting effects by binding to the α subunit of its receptor, thereby activating the kinase in the β subunit. This event leads to tyrosyl phosphorylation of its cytosolic substrate, insulin receptor substrate 1 (IRS-1), which in turn associates with and activates phosphatidylinositol (PI) 3-kinase. The clinical use of ACE inhibitors has been associated with increased insulin sensitivity. However, the exact molecular mechanism is unknown. In the present study, we examined the phosphorylation status of the insulin receptor and IRS-1, as well as the association between IRS-1 and PI 3-kinase in the liver and muscle of 20-month-old rats treated acutely with captopril, using immunoprecipitation with antipeptide antibodies to the insulin receptor and IRS-1, and immunoblotting with antiphosphotyrosine and anti-PI 3-kinase antibodies. Insulin stimulation increased receptor autophosphorylation to 462 ± 253% (P < 0.05) in the liver and 697 ± 78% (P < 0.001) in the muscle of ACE inhibitor-treated rats. There were also increases to 250 ± 17% (P < 0.001) and 280 ± 50% (P < 0.05) in the insulin-stimulated IRS-1 phosphorylation levels in the liver and muscle, respectively, of animals treated with captopril. The insulin-stimulated IRS-1 association with PI 3-kinase rose to 305 ± 20% (P < 0.001) in liver and 267 ± 48% (P < 0.05) in muscle. Losartan, an ANG receptor blocker, had no significant effect on insulinstimulated IRS-1 phosphorylation in both tissues. The acute administration of bradykinin increased insulinstimulated tyrosine phosphorylation of the insulin receptor and IRS-1 in the liver and muscle. These data demonstrate that ACE inhibitors modulate the early steps of insulin signaling, and that this effect may be simulated by the administration of bradykinin.
Instance Segmentation Based on Superpixel Module and Attention Module

instance segmentation has become a hot topic in computer vision, which is a combination of semantic image segmentation and object detection. In this work, we propose a new network MaskSAN for instance segmentation, which has three outputs: box prediction, semantic segmentation, and classification score. In this network, Superpixel-pooling is used to increase the spatial prior information of features and enhance the edge performance of segmentation. In addition, the network also combines the recently popular attention modules to enhance the feature extraction module of the network and the context information in feature extraction. Without reducing the speed, the accuracy of segmentation and detection is improved. The network makes full use of the image’s own information and enhances the constraints. Our proposed network performs experiments on the public coco dataset and has excellent performance in detection and segmentation.
Population Spatial Dynamics of Larix potaninii in Alpine Treeline Ecotone in the Eastern Margin of the Tibetan Plateau, China

The high-altitude treeline is known to be sensitive to climate variability, and is thus considered as a bio-monitoring indicator of climate change. However, our understanding of the population dynamics and the cumulative climate-change effects on the alpine treeline ecotone in recent decades is limited. Here, we investigated the population dynamics of Larix potainii on the south- and north-facing slopes in the alpine treeline ecotone in the eastern margin of the Tibetan Plateau, China, including treeline position, population density, and tree recruitment. Results showed that on both south- and north-facing slopes, the treeline did not show a significant advancement in the past four decades. The population was dominated by young individuals, which tend to be established in the lower areas. Larix, here, tends to be clustered, especially in the upper areas. However, population density increased dramatically only on north-facing slopes. Larix here suffer from the stressful environment, but the warmer winter due to climate warming could facilitate the vertical growth of seedlings and saplings. Aggregated spatial patterns also provide a positive feedback in ameliorating the harsh environment. The slope-climate-moisture interactions have a pronounced impact on tree recruitment, including snow-limited tree establishment on the north-facing slopes and moisture-limited tree establishment on the south-facing slopes.
A Review of Object Oriented Database Concepts and their Implementation

Object Oriented design and databases has attracted a great deal of attention in recent years. This article outlines and discusses the semantic data principles used inter alia in understanding Object Oriented concepts. To illustrate and lend substance to this discussion a list is presented of OODBMS implementations. Their weaknesses and strengths are analysed. And their suitability for specific applications is assessed. Finally we offer some conclusions about research in this area and the directions in which further development should proceed.
Intergeneric Coaggregation among Drinking Water Bacteria: Evidence of a Role for Acinetobacter calcoaceticus as a Bridging Bacterium

ABSTRACT Intergeneric coaggregation of drinking water bacteria was tested. Acinetobacter calcoaceticus was found not only to autoaggregate but also to coaggregate with four of the five other isolates (Burkholderia cepacia, Methylobacterium sp., Mycobacterium mucogenicum, Sphingomonas capsulata, and Staphylococcus sp.). In its absence, no coaggregation was found. Interactions were lectin-saccharide mediated. The putative bridging function of A. calcoaceticus was evidenced by multispecies biofilm studies, through a strain exclusion process.
A novel Si-based X'tal oscillator device using 3D integration technologies

A novel Si-based X'tal oscillator device (1.2 mm × 1.0 mm) is demonstrated by using 3D integration technologies. It is distinct from conventional X'tal oscillator device with ceramics and metal lid. The novel Si-based X'tal oscillator device shows no leakage path, and passes the hermetic encapsulation test and reliability investigation. In addition, the novel device shows the excellent electrical characteristics and provides the possibility to replace the conventional fabrication approach for the next generation products.
Release of glial fibrillary acidic protein is related to the neurovascular status in acute ischemic stroke

This study aimed at an analysis of glial fibrillary acidic protein (GFAP) in acute ischemic stroke, its association with the neurovascular status and its potential value as monitoring parameter. In 53 consecutive patients, serial venous blood samples were taken on admission, 6, 12, 18, 24, 48, 72, 96, and 120 h after stroke onset. The neurovascular status was assessed by repetitive extracranial and transcranial duplex sonography. Neurologic deficits were quantified by the National Institutes of Health stroke scale, and functional outcome was assessed with the modified Rankin Scale. Mean GFAP values were elevated from admission on with highest levels 48 h after stroke onset. GFAP release was highly correlated with severity of neurologic deficits and infarct volume. In patients with persistent middle cerebral artery occlusion, GFAP increased significantly compared with patients with normal sonographic findings (P = 0.019) and recanalization after thrombolysis resulted in a significant reduced increase (P = 0.038). GFAP concentrations were associated with the functional outcome after 3 months. Release kinetics of GFAP are associated with patients clinical deficits and infarct volume, depend on the neurovascular status on admission and on early recanalization after thrombolysis, and may be used as an additional predictor of the early course and functional outcome.
Gross enamel hypoplasia in molars from subadults in a 16th-18th century London graveyard.

Dental Enamel Hypoplasia has long been used as a common nonspecific stress indicator in teeth from archaeological samples. Most researchers report relatively minor linear and pitted hypoplastic defects on tooth crown surfaces. In this work we report a high prevalence and early age of onset of extensive enamel defects in deciduous and permanent molars in the subadults from the post-medieval cemetery of Broadgate, east central London. Analysis of the dentition of all 45 subadults from the cemetery, using both macroscopic and microscopic methods, reveals disturbed cusp patterns and pitted, abnormal and arrested enamel formation. Forty-one individuals from this group (93.2%) showed some evidence of enamel hypoplasia, 28 of them showing moderate or extensive lesions of molars, deciduous or permanent (63.6% of the sample). Scanning Electron Microscope images reveal many molars with grossly deformed cuspal architecture, multiple extra cusps and large areas of exposed Tomes' process pits, where the ameloblasts have abruptly ceased matrix production, well before normal completion. This indented, rough and poorly mineralized surface facilitates both bacterial adhesion and tooth wear, and when such teeth erupt fully into the mouth they are likely to wear and decay rapidly. We suggest that this complex combination of pitted and plane-form lesions, combined with disruption of cusp pattern and the formation of multiple small cusps, should henceforth be identified as "Cuspal Enamel Hypoplasia. "
Methods and algorithms optimization of adaptive traffic control in the virtual data center

Nowadays the cloud computing technology is developing steadily and new approaches for work organization are still appearing. One of the problems of cloud computing technology is the control of the traffic in cloud applications and services in the network environment of virtual data center. The advantage of modern infrastructure's virtualization is the possibility to use the software-defined networks and software-defined data storages. But the existing solutions algorithmic optimization does not take into account the peculiarities of routing the heterogeneous flows network traffic. The optimization task of traffic distribution in cloud applications and services is solved by using software-defined infrastructure and virtual data centers. We suggested the simulation model for the traffic in software-defined segments of data center networks, involved in user application and service requests within a network environment including heterogeneous cloud platform and software-defined data storages. Our model allows to implement the traffic management algorithm of cloud applications and to optimize the access to storage systems through the effective use of data transmission channels. In the course of experimental studies we found that the use of our algorithm leads to a decrease in response time of cloud applications and services, and, so increasing the productivity of user request processing and reducing the number of refusals.
Data gathering in wireless sensor networks with ferry nodes

Mobile ferries are an alternative way for collecting data from dispersed sensor nodes especially in large-scale networks. Unlike data collection via multi-hop forwarding among the nodes, ferries travel across the sensing field and collect data from the sensing nodes. The advantage of using a ferry based approach is that, it eliminates the need for multi-hop forwarding of data, and as a result energy consumption at the nodes is significantly reduced. However, this increases data delivery latency and as such might not be suitable for all applications. In this paper we survey the recent progress of using mobile ferry nodes for data gathering in WSNs addressing two main areas, determining the path of the ferry and the scheduling when to dispatch the ferry to collect data from sensors. We also highlight challenges facing the deployment of mobile ferries in wireless sensor networks.
ras may mediate mammary cancer promotion by high fat.

High fat consumption has been implicated as a risk factor for breast cancer. Experimental mammary carcinogenesis studies have demonstrated that the effect of high fat consumption is mainly exerted on the postinitiation stage of the disease process. We report data that have recalled in the formulation of a new hypothesis about the effect of dietary fat on mammary carcinogenesis, namely, that it promotes the development of a subpopulation of cells lacking a specific pathogenetic characteristic. In comparison with animals fed a low-fat diet, female Sprague-Dawley rats fed high-fat diets during the promotional stage developed significantly more (number and proportion) 1-methyl-1-nitrosourea-induced mammary adenocarcinomas that did not contain a codon 12 GGA-->GAA mutation in the c-Ha-ras protooncogene. The effect was independent of the types of fat fed, i.e., corn oil vs. fish oil. A model is presented to account for the preferential promotional effect of high fat consumption on 1-methyl-1-nitrosourea-initiated mammary epithelial cells. The hypothesis that the level of dietary fat consumed affects the proportion of mammary carcinomas that occur with a particular pathogenetic characteristic, in this case, the presence or absence of a Ha-ras point mutation, has important implications on the direction of future investigations concerning fat and cancer risk.
REPLICATION OF MEASLES VIRUS IN A CELL CULTURE FROM A GLIOBLASTOMA OF HUMAN ORIGIN

A cell culture from a glioblastoma of human origin infected with the Edmonston strain of measles virus produced and released infectious measles virus. All cellular types seemed to be involved in the process of virus replication. Staining with hematin-eosin revealed the presence of eosinophilic intracytoplasmic and intranuclear inclusions. Examination with the electron microscope revealed viral nucleocapside in the cytoplasm and, rarely, in the nuclei of infected cells.
Phantom plumes in Europe and the circum-Mediterranean region

Anorogenic magmatism of the circum-Mediterranean area (the Tyrrhenian Sea, Sardinia, Sicily Channel, and the Middle East) and of continental Europe (the French Massif Central, Eifel, the Bohemian Massif, and the Pannonian basin) has been proposed to be related to the presence of one or more mantle plumes. Such conclusions based on geochemical data and seismic tomography are not fully justified because (1) a given chemical and isotopic composition of a magma can be explained by different petrogenetic models, (2) a given petrogenetic process can produce magmas with different chemical and isotopic composition, (3) tomographic studies do not furnish unique results (i.e., different models give different results), and (4) the commonly adopted interpretation of seismic wave velocity anomalies exclusively in terms of temperature is not unique; velocities are also dependent on other parameters, such as composition, melting, anisotropy, and anelasticity. Tomography and geochemistry are powerful tools but must be used in an interdisciplinary way, in combination with geodynamics and structural geology. Alone they cannot provide conclusive evidence for or against the existence of mantle plumes. The existence of large and/or extensive thermal anomalies under Europe is here considered unnecessary, because other models, based on the existence of upper-mantle heterogeneity, can explain the major-element, trace-element, and isotopic variability of the magmas. Volcanism in central Europe (the French Massif Central, Germany, and the Bohemian Massif) is concentrated in Cenozoic rifted areas and is here interpreted as the result of passive asthenosphere upwelling driven by decompression. Similarly, anorogenic magmatism in Sardinia, the Tyrrhenian Sea, and the Pannonian basin is explained as the result of lithospheric stretching in a back-arc geodynamic setting. The most important factors determining the locus and, in part, the geochemical characteristics of magmatic activity are the Moho and the lithosphere-asthenosphere boundary depths. Where both are shallowed by tectonic processes (e.g., in rift zones or back-arc basins), passive upwelling of asthenospheric mantle can explain the magmatic activity.