Miracle-dz/UniFAR-FTUs huggingface dataset:
Robust flight control design using dynamic inversion and structured singular value synthesis

A direct methodology for the design of flight control systems is introduced. The design approach uses a control selector and an inner/outer loop structure to achieve robustness and performance across the flight envelope. A control selector normalizes control effectiveness with respect to generalized inputs. An inner loop uses dynamic inversion to equalize plant dynamics across the flight envelope. An outer loop is designed around this equalized plant, using mu -synthesis to achieve performance and robustness goals. The methodology is applied to the design of a manual flight control system for the lateral axis of a fighter aircraft. Analysis shows that the inner/outer loop approach produces designs with excellent performance and robustness for a broad range of operating conditions. The direct incorporation of design goals such as flying qualities requirements and the elimination of gain scheduling make this direct methodology an effective and efficient alternative to traditional flight control design approaches. >
Strategic information system plan for the implementation of information technology at Polytechnic “API” Yogyakarta

Strategic Planning of information system is now of the key in achieving the institution goals, as must be aligned with the business strategy being executed. Information Systems/Information Technology (IS/IT) is becomes as one of the strategy in the higher education institution to improve the quality of education and services to all stakeholders to be an excellent and competitive Polytechnic. Development of Strategic planning model of information systems to be discussed in this study is using Ward & Peppard method. Ward & Peppard method is a model used to develop an information system strategic planning in an institution. Strategic direction that they want to be achieved is a development of data/information, application, and technology in information utilization to support all business processes have already there to be an integrated information system. This result of the study showed a model of Strategic Information System Planning in higher education institutions that are aligned with its business strategy. The results of this mapping need further elaboration IS/IT in line with business strategy institution using Analisis SWOT, and McFarlan Strategic Grid. The needs for IS/IT that emerge later is to be inventoried to be carried out in accordance with the strategic management IS/IT.
Genetic variation and susceptibility to infection: the red cell and malaria

There is now convincing evidence that the extremely high frequencies of certain genetic disorders of the red cell involving haemoglobin, the red‐cell membrane, or its metabolic pathways reflect relative resistance to malaria over thousands of years. At least some progress has been made towards an understanding of the cellular mechanisms involved, although much remains to be learnt. As well as the extremely valuable information that this field is providing about how exposure to infection has moulded the current structure of the human genome, recent research in this field is starting to provide some valuable new approaches to the better control of parasitic and other infections that remain a major global health problem.
Measurement of firefly luciferase reporter gene activity from cells and lysates using Escherichia coli arsenite and mercury sensors.

The structural gene encoding firefly luciferase from Photinus pyralis is a widely used reporter both in traditional monitoring of gene expression and in bacterial sensors. Its activity can be detected from living cells (in vivo) without disruption or from cell-free lysate (in vitro). We compared the two measurement methods by using an overall toxicity detecting strain Escherichia coli MC1061(pCSS810), a mercury-sensing strain E. coli MC1061(pTOO11), and two new arsenic sensor strains MC1061(pTOO31) and AW3110(pTOO31) which were constructed for this study. Plasmid pTOO31 was constructed by inserting the ars promoter and the arsR gene from plasmid R773 to control firefly luciferase gene expression. Both in vivo and in vitro methods correlated well with the strains tested [correlation coefficients R = 0.99484 and 0.99834] and gave highly comparable results with standard solutions of arsenite or mercury ions and from six environmental water samples spiked with the ions. Use of the in vivo method resulted in lower variation between replicates of the same sample (CVs ranging from 3.9 to 7.2%) and also between different samples (from 8.6 to 25.9%) compared to the in vitro method (CVs ranging from 8.6 to 17.8% for replicates and from 13.1 to 36.3% for different samples).
X‐Irradiation improves mdx mouse muscle as a model of myofiber loss in DMD

The mdx mouse, although a genetic and biochemical homologue of human Duchenne muscular dystrophy (DMD), presents a comparatively mild histopathological and clinical phenotype. These differences are partially attributable to the greater efficacy of regeneration in the mdx mouse than in DMD muscle. To lessen this disparity, we have used a single dose of X‐irradiation (16 Gy) to inhibit regeneration in one leg of mdx mice. The result is an almost complete block of muscle fiber regeneration leading to progressive loss of muscle fibers and their replacement by loose connective tissue. Surviving fibers are mainly peripherally nucleated and, surprisingly, of large diameter. Thus, X‐irradiation converts mdx muscle to a model system in which the degenerative process can be studied in isolation from the complicating effect of myofiber regeneration. This system should be of use for testing methods of a leviating the myofiber degeneration which is common to mdx and DMD.
The Adaptation of Hearing Parents of Hearing-Impaired Youths

This study evaluated the emotional and marital adjustment of hearing parents of hearing-impaired youths. Participants included mothers and fathers of hearing-impaired youths and mothers and fathers of hearing youths. In contrast with expectations based on clinical impressions reported in the literature, parents of hearing-impaired youths reported less symptomatology than did parents of hearing youths, and there were no differences in the marital satisfaction of parents in intact families.Moreover, parental adjustment was not associated with the duration of time since the child was diagnosed as hearing impaired. In addition, hierarchical multiple regression analyses revealed that family cohesion was associated with low maternal symptomatology and high marital satisfaction for both spouses. For mothers, low symptomatology was associated with low stress and female gender of child; high marital satisfaction also was linked with a less severe degree of hearing loss in the youth.
Glucose repression of enterotoxins A, B and C and other extracellular proteins in staphlyococci in batch and continuous culture.

The production of enterotoxins, lipase and total extracellular protein by four strains of Staphylococcus aureus grown in batch culture at a controlled pH of 6.5 in a completely defined medium was markedly reduced by glucose or glycerol constantly maintained at 0.I M. A concomitant increase in the production of deoxyribonuclease, up to 13-fold, showed however that not all extracellular proteins are under the same control mechanism. The presence of glucose and glycerol in the medium also resulted in a rapid increase in the specific growth rate. However, growth of S. aureus s6 in Mgilimited continuous culture showed that glucose repression of enterotoxin B when the growth rate was held constant was more than twice that in batch culture. Therefore glucose repression can occur independently of an increase in growth rate. The specific rate of production of enterotoxin B, lipase, deoxyribonuclease, beta-haemolysin and total extracellular protein by S. aureus s6 increased as the growth rate increased from 0.07 to 0.24 h-1. Non-replicating cells grown in the absence of glucose produced considerable amounts of enterotoxin, and production was not repressed by the presence of glucose in the resuspension medium. In contrast, no enterotoxin B or C was obtained from nonreplicating cells grown in the presence of glucose. Chloramphenicol completely inhibited enterotoxin production by non-replicating cells, indicating that synthesis of new protein was required.
Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel.

We synthesized a novel anticancer agent MS-247 (2-[[N-[1-methyl-2-[5-[N-[4-[N,N-bis(2-chloroethyl) amino] phenyl]] carbamoyl]-1H-benzimidazol-2-yl] pyrrol-4-yl] carbamoyl] ethyldimethylsulfonium di-p-toluenesulfonate) that has a netropsin-like moiety and an alkylating residue in the structure. We evaluated antitumor activity of MS-247 using a human cancer cell line panel coupled with a drug sensitivity database and subsequently using human cancer xenografts. The average MS-247 concentration required for 50% growth inhibition against a panel of 39 cell lines was 0.71 microM. The COMPARE analysis revealed that the differential growth inhibition pattern of MS-247 significantly correlated with those of camptothecin analogues and anthracyclins, indicating that MS-247 and the two drug groups might have similar modes of action. MS-247 exhibited remarkable antitumor activity against various xenografts. A single i.v. injection of MS-247 significantly inhibited the growth of all 17 xenografts tested, which included lung, colon, stomach, breast, and ovarian cancers. In many cases, MS-247 was more efficacious than cisplatin, Adriamycin, 5-fluorouracil, cyclophosphamide, VP-16, and vincristine and was almost comparable with paclitaxel and CPT-11; these are the most clinically promising drugs at present. MS-247 was noticeably more effective than paclitaxel (in HCT-15) and CPT-11 (in A549, HBC-4, and SK-OV-3). The toxicity of MS-247, indicated by body weight loss, was reversible within 10 days after administration. The MS-247 mode of action showed DNA binding activity at the site where Hoechst 33342 bound, inhibited topoisomerases I and II (as expected by the COMPARE analysis) blocked the cell cycle at the G2-M phase, and induced apoptosis. These results indicate that MS-247 is a promising new anticancer drug candidate to be developed further toward clinical trials.
RF Modeling for FDSOI MOSFET and Self Heating Effect on RF Parameter Extraction

In this paper, a BSIMSOI RF gate resistance model for FDSOI MOSFET is introduced and verified. With the addition of the gate resistance model, the RF characteristic of FDSOI MOSFET could be modeled well. Self-heating effect (SHE) will affect RF data fitting significantly. A simple method to extract thermal resistance is proposed.
PKD2, a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein

A second gene for autosomal dominant polycystic kidney disease was identified by positional cloning. Nonsense mutations in this gene (PKD2) segregated with the disease in three PKD2 families. The predicted 968-amino acid sequence of the PKD2 gene product has six transmembrane spans with intracellular amino- and carboxyl-termini. The PKD2 protein has amino acid similarity with PKD1, the Caenorhabditis elegans homolog of PKD1, and the family of voltage-activated calcium (and sodium) channels, and it contains a potential calcium-binding domain.
La familia como respuesta a las demandas de individualización: ambivalencias y contradicciones

Para evaluar los temas relacionados con la llamada «emancipacion» de la juventud, queremos presentar la comparacion entre la situacion y las vivencias de los padres (antes), la evolucion que ha tenido lugar y las estrategias, perspectivas y vivencias de la juventud actual. Que significados tenian «antes» las relaciones en la familia? : contar con un modelo mas o menos estable de funcionamiento, de comportamiento, de formacion y de aprendizaje de una profesion, de metas de formacion, de fases de formacion hasta llegar a la jubilacion. Modelos de comportamiento y modelos de significacion de la vida, tipos de union existentes entre los grupos primarios, ligaduras ideologicas cerradas (partidos, Iglesia), transicion a formas de vida estable (matrimonio), movilidad reducida (pocos cambios en las cualificaciones o movilidad local). «Hoy» las dependencias son cambiantes y diferenciadas como consecuencia de la inseguridad y de la incerteza en el futuro, en las formas de vida y en los comportamientos Para poder asegurar su existencia y crear nuevas formas de vida o adaptarse a los diferentes estandares, los miembros de las familias permanecen juntos mucho mas tiempo (la familia como hotel, como soporte), como respuesta a las demandas de la individualizacion, como una forma de amortiguar los riesgos y/o asegurarse ante los mismos. Se pretende hacer una aportacion al analisis de las ambivalencias en la que viven las madres y los padres que, entre 1970 y 1989, tenian la misma edad de los jovenes y las jovenes que, entre 1994 y 2004, tienen entre 20 y 25 anos.
Humanoid Robot Head Design Based on Uncanny Valley and FACS

Emotional robots are always the focus of artificial intelligence (AI), and intelligent control of robot facial expression is a hot research topic. This paper focuses on the design of humanoid robot head, which is divided into three steps to achieve. The first step is to solve the uncanny valley about humanoid robot, to find and avoid the relationship between human being and robot; the second step is to solve the association between human face and robot head; compared with human being and robots, we analyze the similarities and differences and explore the same basis and mechanisms between robot and human analyzing the Facial Action Coding System (FACS), which guides us to achieve humanoid expressions. On the basis of the previous two steps, the third step is to construct a robot head; through a series of experiments we test the robot head, which could show some humanoid expressions; through human-robot interaction, we find people are surprised by the robot head expression and feel happy.
National Standards for Diabetes Self-Management Education

D iabetes self-management education (DSME) is a critical element of care for all people with diabetes and is necessary in order to improve patient outcomes. The National Standards for DSME are designed to define quality diabetes self-management education and to assist diabetes educators in a variety of settings to provide evidence-based education. Because of the dynamic nature of health care and diabetes-related research, these Standards are reviewed and revised approximately every 5 years by key organizations and federal agencies within the diabetes education community. A Task Force was jointly convened by the American Association of Diabetes Educators and the American Diabetes Association in the summer of 2006. Additional organizations that were represented included the American Dietetic Association, the Veteran’s Health Administration, the Centers for Disease Control and Prevention, the Indian Health Service, and the American Pharmaceutical Association. Members of the Task Force included a person with diabetes; several health services researchers/ behaviorists, registerednurses, and registered dietitians; and a pharmacist. The Task Force was charged with reviewing the current DSME standards for their appropriateness, relevance, and scientific basis. The Standards were then reviewed and revised based on the available evidence and expert consensus. The committee convened on 31 March 2006 and 9 September 2006, and the Standards were approved 25 March 2007.
Aliskiren Enhances the Protective Effects of Valsartan Against Cardiovascular and Renal Injury in Endothelial Nitric Oxide Synthase–Deficient Mice

The protective effect of aliskiren, a direct renin inhibitor, against hypertensive cardiovascular and renal injury remains to be defined. This study was undertaken to examine the protective effects of the combination of aliskiren and valsartan, an angiotensin receptor blocker, against cardiovascular and renal injury. Endothelial NO synthase–deficient mice, subjected to cuff injury of femoral artery, were divided into 5 groups and were treated with the following: (1) vehicle; (2) aliskiren (25 mg/kg per day); (3) valsartan (8 mg/kg per day); (4) combined aliskiren (12.5 mg/kg per day) and valsartan (4 mg/kg per day); and (5) hydralazine (10 mg/kg per day) for 4 weeks. Aliskiren and valsartan alone markedly and similarly suppressed cardiac hypertrophy, inflammation and fibrosis, and coronary remodeling; prevented cuff injury–induced arterial intimal thickening; and reduced urinary albumin excretion, glomerular inflammation, and glomerulosclerosis in endothelial NO synthase–deficient mice. These beneficial effects of aliskiren and valsartan were associated with the significant attenuation of oxidative stress in these tissues. Hence, aliskiren and valsartan markedly exert the protective effects against cardiovascular and renal injury through the reduction of oxidative stress. Furthermore, compared with monotherapy with aliskiren or valsartan, the combination of a half dose of these drugs more greatly improved the above-mentioned cardiovascular and renal injuries of endothelial NO synthase–deficient mice, which were associated with greater attenuation of tissue oxidative stress by the combination therapy. Thus, the combination of aliskiren and valsartan exerts the synergistic organ-protective effects through synergistic attenuation of oxidative stress. The combination of aliskiren and valsartan seems to be a promising therapeutic strategy for hypertensive organ injury caused by endothelial NO synthase dysfunction.
A Capital Theory of School Effectiveness and Improvement

A new theory of school effectiveness and improvement is outlined, based on the master concepts of intellectual capital, social capital and leverage, linked with the conventional concept of institutional outputs. Each master concept is defined in terms of two subsidiary concepts. Twelve specifically educational concepts are set within this framework to provide the theory. It is proposed that, through a simplified model, the range and fertility of the theory can be exemplified and tested in three specific casesthe changing nature of school effectiveness and improvement in knowledge economies, citizenship education and teacher effectiveness.
Measurement of Baroreceptor-Mediated Effects on Heart Rate Variability in Fetal Sheep

To determine if alterations in arterial pressure influenced fetal heart rate variability (HRV), experiments were carried out in chronically catheterized fetal sheep aged 128–138 d. Arterial pressure was raised or lowered by intravenous infusion of phenylephrine or sodium nitroprusside, and the effects on heart rate (HR) and HRV were measured (HRV, as the coefficient of variation (CV) in mean pulse interval or by power spectral analysis). Experiments were carried out before and during β-adrenoceptor blockade with propranolol or before and during cardiac vagal blockade with atropine. There were positive relationships between mean arterial pressure and HRV (slope = 0.074 ± 0.001, r = 0.81 ± 0.06, p < 0.001, measured as the CV of pulse interval) and between mean arterial pressure and power spectral density (slope = 4 ± 0.5, r = 0.89 ± 0.02, p < 0.001) in the frequency range 0.04–0.08 Hz. β-adrenoceptor blockade had no effect on these relationships, but they were abolished by cardiac vagal blockade. The sigmoid relationship between fetal HR and mean arterial pressure, i.e. the cardiac baroreflex, was affected, however, by blockade of cardiac sympathetics and abolished by blockade of cardiac vagal activity. Thus, fetal HRV was affected by alterations in arterial pressure, and these effects depended on the integrity of the cardiac vagus, not on alterations in cardiac sympathetic activity. Therefore, although baroreflex control of fetal HR depends on the integrity of both sympathetic and parasympathetic efferent pathways, baroreceptor-induced changes in HRV depend only on the cardiac vagus.
Pressure-induced critical behavior of KMnF3 close to Pc=3.1 GPa: X-ray diffraction results.

The critical behavior of ${\mathrm{KMnF}}_{3}$ close to the pressure-induced cubic-to-tetragonal structural phase transition at ${\mathit{P}}_{\mathit{c}}$=3.1 GPa has been studied by single-crystal x-ray diffraction. The pressure dependence of a primary order parameter has been determined from superlattice Bragg intensities and was found to fulfill the power law Q=A(P-${\mathit{P}}_{\mathit{c}}$${)}^{\mathrm{\ensuremath{\beta}}}$. The transition with a small discontinuity of the intensities close to ${\mathit{P}}_{\mathit{c}}$ shows deviations from the classical behavior similarly as in the temperature-dependent transition at 186 K, where the domain structure considerably affects the values of the critical parameters. However, the pressure inhibits formation of large, single domains of definite orientation. Instead, increased width of diffraction profiles points to the appearance of numerous, narrow domains which may influence the character of the transition. \textcopyright{} 1996 The American Physical Society.
Key, Chord, and Rhythm Tracking of Popular Music Recordings

In this article, we propose a framework to analyze a musical audio signal (sampled from a popular music CD) and determine its key, provide usable chord transcriptions, and obtain the hierarchical rhythm structure representation comprising the quarternote, half-note, and whole-note (or measure) levels. This framework is just one specific aspect of the broader field of content-based analysis of music. There would be many useful applications of content
Cyber Physical System: Architecture, applications and research challenges

Cyber world and physical world were considered as two different entities in the past decade. However, researchers have found that these two entities are closely correlated with each other after integration of sensor/actuators in the cyber systems. Cyber systems became responsive to the physical world by enabling real time control emanating from conventional embedded systems, thus emerging a new research paradigm named Cyber Physical System (CPS). In this article, we investigate major challenges in the integration of cyber world with physical world and its applications. In addition, we propose an architecture which contains several modules supporting the CPS. We found that every module in our proposed architecture has its own significance and can be applied to various applications.