Miracle-dz/UniFAR-FTUs huggingface dataset:
Information Technologies in Public Administration

There are visible changes in the world organization, environment and health of national conscience that create a background for discussion on possible redefinition of global, state and regional management goals. The author applies the sustainable development criteria to a hierarchical management scheme that is to lead the world community to non-contradictory growth. Concrete definitions are discussed in respect of decision-making process representing the state mostly. With the help of systems analysis it is highlighted how to understand who would carry the distinctive sign of world leadership in the nearest future.
A process of convergent amplification and tissue‐specific expression dominates the evolution of toxin and toxin‐like genes in sea anemones

Members of phylum Cnidaria are an ancient group of venomous animals and rely on a number of specialized tissues to produce toxins in order to fulfil a range of ecological roles including prey capture, defence against predators, digestion and aggressive encounters. However, limited comprehensive analyses of the evolution and expression of toxin genes currently exist for cnidarian species. In this study, we use genomic and transcriptomic sequencing data to examine gene copy number variation and selective pressure on toxin gene families in phylum Cnidaria. Additionally, we use quantitative RNA‐seq and mass spectrometry imaging to understand expression patterns and tissue localization of toxin production in sea anemones. Using genomic data, we demonstrate that the first large‐scale expansion and diversification of known toxin genes occurs in phylum Cnidaria, a process we also observe in other venomous lineages, which we refer to as convergent amplification. Our analyses of selective pressure on sea anemone toxin gene families reveal that purifying selection is the dominant mode of evolution for these genes and that phylogenetic inertia is an important determinant of toxin gene complement in this group. The gene expression and tissue localization data revealed that specific genes and proteins from toxin gene families show strong patterns of tissue and developmental‐phase specificity in sea anemones. Overall, convergent amplification and phylogenetic inertia have strongly influenced the distribution and evolution of the toxin complement observed in sea anemones, while the production of venoms with different compositions across tissues is related to the functional and ecological roles undertaken by each tissue type.
Energy-Efficient Power Control in Cell-Free and User-Centric Massive MIMO at Millimeter Wave

In a cell-free massive MIMO architecture a very large number of distributed access points simultaneously and jointly serves a much smaller number of mobile stations; a variant of the cell-free technique is the user-centric approach, wherein each access point just serves a reduced set of mobile stations. This paper introduces and analyzes the cell-free and user-centric architectures at millimeter wave frequencies, considering a training-based channel estimation phase, and the downlink and uplink data transmission phases. First of all, a multiuser clustered millimeter wave channel model is introduced in order to account for the correlation among the channels of nearby users; second, an uplink multiuser channel estimation scheme is described along with low-complexity hybrid analog/digital beamforming architectures. Third, the non-convex problem of power allocation for downlink global energy efficiency maximization is addressed. Interestingly, in the proposed schemes no channel estimation is needed at the mobile stations, and the beamforming schemes used at the mobile stations are channel-independent and have a very simple structure. Numerical results show the benefits granted by the power control procedure, that the considered architectures are effective, and permit assessing the loss incurred by the use of the hybrid beamformers and by the channel estimation errors.
Heads and Tails of Earnings Management: Quantitative Analysis in Emerging Countries

Earnings management is a globally used tool for long-term profitable enterprises and for the apparatus of reduction of bankruptcy risk in developed countries. This phenomenon belongs to the integral and fundamental part of their business finance. However, this has still been lax in emerging countries. The models of detections of the existence of earnings management are based on discretionary accrual. The goal of this article is to detect the existence of earnings management in emerging countries by times series analysis. This econometric investigation uses the observations of earnings before interest and taxes of 1089 Slovak enterprises and 1421 Bulgarian enterprises in financial modelling. Our findings confirm the significant existence of earnings management in both analyzed countries, based on a quantitative analysis of unit root and stationarity. The managerial activities are purposeful, which is proven by the existence of no stationarity in the time series and a clear occurrence of the unit root. In addition, the results highlight the year 2014 as a significant milestone of change in the development of earnings management in both countries, based on homogeneity analyses. These facts identify significant parallels between Slovak and Bulgarian economics and business finance.
Endometriosis and the menopause: why the question merits our full attention

Abstract As an estrogen-dependent disease, endometriosis was thought to become less active or regress with the onset of the menopause. However, based on some new data, we are discovering that this pathology can emerge or reappear at this period of life. Clinicians must consider it as a possible cause for cases of pelvic pain, and heavy bleeding. Authors have described a possibility of transformation of the intraperitoneal proliferation into a malignant type with ovarian, bowel and even lung metastasis. The risk of transformation into an ovarian cancer is around 2 or 3%. The role of menopausal hormonal therapy will be discussed as in recurrence in the case of residue existence, especially after incomplete surgery. Is it possible to prescribe hormonal therapy to a menopausal women suffering climacteric symptoms as it could trigger a recurrence of endometriosis and even an increased risk of malignant degeneration? This remains unclear. It is an unresolved therapeutic dilemma; the choice between surgery or medical treatment?
An Note on Why Geographically Weighted Regression Overcomes Multidimensional-Kernel-Based Varying-Coefficient Model

It is widely known that geographically weighted regression(GWR) is essentially same as varying-coefficient model. In the former research about varying-coefficient model, scholars tend to use multidimensional-kernel-based locally weighted estimation(MLWE) so that information of both distance and direction is considered. However, when we construct the local weight matrix of geographically weighted estimation, distance among the locations in the neighbor is the only factor controlling the value of entries of weight matrix. In other word, estimation of GWR is distance-kernel-based. Thus, in this paper, under stationary and limited dependent data with multidimensional subscripts, we analyze the local mean squared properties of without any assumption of the form of coefficient functions and compare it with MLWE. According to the theoretical and simulation results, geographically-weighted locally linear estimation(GWLE) is asymptotically more efficient than MLWE. Furthermore, a relationship between optimal bandwith selection and design of scale parameters is also obtained.
Degradation of 4‐chlorophenol by BM Fe/Cu‐O2 system: The symbiosis of ·O2- and ·OH radicals

In this study, Fe/Cu bimetal composite was prepared by high‐energy ball milling (BM) method for the removal of refractory organics. The BM Fe/Cu bimetal was characterized by SEM‐EDS, XRD, and XPS. Evenly distributed Fe and Cu was observed in the EDS mapping. In contrasting experiments, the removal rate of 4‐chlorophenol (4‐CP) by BM Fe/Cu materials was about 10‐fold faster than that by chemical substitution deposition (CSD) of Fe/Cu material. Complete 4‐CP removal and 66.7% of total organic carbon (TOC) mineralization in the BM Fe/Cu–O2 system were achieved. Dissolved oxygen plays a crucial role for 4‐CP degradation through the in situ generation of reactive oxygen species (ROS) such as H2O2, ·OH, and ·O2- via oxygen activation reactions. The predominant reactive radicals were identified to be ·O2- and ·OH through ESR technique and inhibition experiments. The coexistence of oxidation and reduction of 4‐CP in the BM Fe/Cu‐O2 system was proposed.
Image search using multilingual texts: a cross-modal learning approach between image and text Maxime Portaz Qwant Research

Multilingual (or cross-lingual) embeddings represent several languages in a unique vector space. Using a common embedding space enables for a shared semantic between words from different languages. In this paper, we propose to embed images and texts into a unique distributional vector space, enabling to search images by using text queries expressing information needs related to the (visual) content of images, as well as using image similarity. Our framework forces the representation of an image to be similar to the representation of the text that describes it. Moreover, by using multilingual embeddings we ensure that words from two different languages have close descriptors and thus are attached to similar images. We provide experimental evidence of the efficiency of our approach by experimenting it on two datasets: Common Objects in COntext (COCO) [19] and Multi30K [7].
Solitary wave solutions of a Whitham-Bousinessq system

The travelling wave problem for a particular bidirectional Whitham system modelling surface water waves is under consideration. This system firstly appeared in [9], where it was numerically shown to be stable and a good approximation to the incompressible Euler equations. In subsequent papers [8, 10] the initial-value problem was studied and wellposedness in classical Sobolev spaces was proved. Here we prove existence of solitary wave solutions and provide their asymptotic description. Our proof relies on a variational approach and a concentration-compactness argument. The main difficulties stem from the fact that in the considered Euler-Lagrange equation we have a non-local operator of positive order appearing both in the linear and non-linear parts.
Hygroscopic behavior of aerosols generated from solutions of 3-methyl-1,2,3-butanetricarboxylic acid, its sodium salts, and its mixtures with NaCl

Abstract. MBTCA (3-methyl-1,2,3-butanetricarboxylic acid), a low-volatile, highly oxidized, secondary-generation product of monoterpenes, is one of the most relevant tracer compounds for biogenic secondary organic aerosols (SOAs). In this study, laboratory-generated, micrometer-sized, pure-MBTCA, mono-/di-/trisodium MBTCA salts and MBTCA–NaCl mixture aerosol particles of four mixing ratios (molar ratios = 1 : 1, 1 : 2, 1 : 3, and 2 : 1) were examined systematically to observe their hygroscopic behavior by varying the relative humidity (RH) using in situ Raman microspectrometry (RMS) assembled with either a see-through impactor, where the particles were deposited on a Si wafer, or a levitation system. The pure MBTCA droplets effloresced at RH = ∼ 30 %–57.8 % and did not deliquesce until RH > 95 %. The mono- and disodium MBTCA salt aerosols did not show clear efflorescence RH (ERH) and deliquescence RH (DRH). In contrast, the trisodium MBTCA salt exhibited ERH = ∼ 44.4 %–46.8 % and DRH = ∼ 53.1 % during the hygroscopic experiment cycle. The mixture aerosols generated from solutions of MBTCA : NaCl = 1 : 1 and 2 : 1 showed no visible ERH and DRH in the see-through impactor because of the partial and total consumption of NaCl, respectively, through chemical reactions during the dehydration process. The mixture particles with a 1 : 1 molar ratio in the levitation system exhibited a clear DRH at ∼ 71 % and ERH at ∼ 50 %. This suggests less reaction between the mixtures and a larger portion of NaCl remaining in the levitation system. The other mixtures of MBTCA : NaCl = 1 : 2 and 1 : 3 displayed single-stage efflorescence and deliquescence at ERH = ∼ 45 %–50 % and DRH = ∼ 74 %, respectively, because of the considerable amount of NaCl present in the mixture aerosols in both systems. Observations and Raman analyses indicated that only monosodium MBTCA salt aerosols could be formed through a reaction between MBTCA and NaCl. The reaction occurred more rapidly with a more elevated concentration of either MBTCA or NaCl, and the controlling factor for the reactivity of the mixtures depended mostly on the availability of H+ dissociated from the MBTCA tricarboxylic acid. The lower degree of reaction of the mixture particles in the levitation system might be caused by the relatively airtight circumstance inside, i.e., less release of HCl. The study revealed that the interactions between the MBTCA and NaCl could modify the properties of the organic acid in the atmosphere, leading to enhanced capability of the probable heterogeneous chemistry in the aqueous aerosols.
Adopting Digital Payment based on the Features and Benefits provided by the Application

Indonesia are facing the era of digitalization where almost all of the citizens today are using technology and digital. The development of information technology has been moving so fast including the payment of using digital system. This research is to analyze the variables of features and benefits towards customer's decision to use in relating to intention to use as the intervening variable. The data collection is done through distribution of questionnaire, where the population is consisted of the customers of Go-Pay digital payment application in Jakarta, Indonesia. This is a descriptive and verification research, the descriptive methods is based on assessment analysis and the verification methods is based on quantitative analysis. The sample determination is done through Purposive Sampling and the analysis technique is using Partial Least Square (PLS). The results show that features and benefits have positive and significant effect towards intention to use, the benefits of the application have the most significant influence towards intention to use compare to the features of the application. The results show that Go-Pay is the digital payment applications in Indonesia which is mostly used by the customers because of the features and benefits provided by the application, that is why Go-Pay is the most popular digital payment application used by the customers.
Changes in the Diagnostic Efficiency of Thyroid Fine-Needle Aspiration Biopsy during the Era of Increased Thyroid Cancer Screening in Korea

Purpose The volume of thyroid cancer screening and subsequent thyroid fine-needle aspiration (FNA) have rapidly increased in South Korea. We analyzed the thyroid cancer diagnoses/thyroid FNA ratio according to the annual number of FNA to evaluate changes in the diagnosticefficiency of FNA. Materials and Methods This was a nationwide population-based retrospective cohort study. The overall thyroid cancer diagnoses/thyroid FNA ratio and annual incremental thyroid cancer diagnoses/incremental thyroid FNA ratio were indirectly calculated using data obtained from the Korea Central Cancer Registry database and the Korean National Health Insurance Service claims database from 2004 to 2012. Pearson correlation analyses were performed to evaluate the strength of linear associations between variables. Results The number of thyroid FNA increased from 28,596 to 177,805 (6.2-fold increase) from 2004 to 2012. The overall thyroid cancer diagnoses/thyroid FNA ratio decreased from 36.5% in 2004 to 25.1% in 2012 and was negatively correlated to the number of FNA (R=‒0.977, p < 0.001). The annual incremental thyroid cancer diagnoses/incremental thyroid FNA ratios (range, 15.3% to 30.7%) were always lower than the overall thyroid cancer diagnoses/thyroid FNA ratio in each year and also worsened according to the increase in the number of FNA (R=‒0.853, p=0.007). Conclusion The diagnostic performance of both overall and annual incremental thyroid FNA worsened, whereas the number of thyroid FNA procedures increased. More sophisticated indications for FNA are required to improve its diagnostic efficiency, considering the increased burden of screening-detected thyroid nodules.
HIV and aging: A primer for NPs

Abstract: Estimates indicate 70% of all individuals with HIV will be age 50 or older by 2030. Chronic conditions, including cardiovascular disease, diabetes mellitus, kidney disease, malignancies, neurocognitive disorders, and osteopenia or osteoporosis, occur more frequently in patients with HIV and have become the leading cause of morbidity in this population. NPs play an integral role in helping this population age healthfully.
Superior Inhibitory Efficacy of Butyrate over Propionate and Acetate Against Human Colon Cancer Cell Proliferation via Cell Cycle Arrest and Apoptosis

Intake of fiber has beneficial properties for gut health. These effects may be due to the increased production of short chain fatty acids (SCFAs) such as acetate, propionate and butyrate during dietary fiber fermentation in the colon. We tested the hypothesis that butyrate exhibits a stronger inhibitory potential against colon cancer cell proliferation compared with acetate and propionate. With a human HCT116 colon cancer cell culture model, we used cell cycle, apoptosis, PCR array, biochemical, western blotting and immunofluorescent assays to determine SCFAs’ inhibitory effects on HCT116 cell proliferation. We determined the half maximal inhibitory concentrations (IC50) of SCFAs in HCT116 cell proliferation by examining cell growth curves. At 24- and 48- hour time points, IC50 (mM) concentrations of acetate, propionate and butyrate were [66.0 and 29.0], [9.2 and 3.6] and [2.5 and 1.3], respectively. Consistent with the greater anti-proliferative effect, butyrate exhibits >3-fold stronger potential for inducing cell cycle arrest (including c-Myc/p21 signaling) and apoptosis when compared with acetate and propionate. Subsequently, we focused on the effect of butyrate on apoptotic gene expression. Using a PCR array analysis, we identified 17 pro-apoptotic genes, 6 anti-apoptotic genes, and 4 cellular mediator genes with >1-fold increase or decrease in mRNA levels out of 93 apoptosis related genes in butyrate-treated HCT116 cells when compared with untreated HCT116 cells. These genes were mainly involved in the tumor necrosis factor alpha receptor, NFκB, caspase recruitment domain-containing protein and B-cell lymphoma-2 regulated pathways. Collectively, we demonstrated a greater inhibitory efficacy of butyrate over propionate and acetate against human colon cancer cell proliferation via cell cycle arrest and apoptosis. This work was supported by U.S. Department of Agriculture, Agricultural Research Service, research project 3062–51,000-056–00D.
Nuts and Bolts of a Realistic Stochastic Geometric Analysis of mmWave HetNets: Hardware Impairments and Channel Aging

Motivated by heterogeneous network (HetNet) design in improving coverage and by millimeter-wave (mmWave) transmission offering an abundance of extra spectrum, we present a general analytical framework shedding light on the downlink of realistic mmWave HetNets consisting of $K$ tiers of randomly located base stations. Specifically, we model, by virtue of stochastic geometry tools, the multi-tier multi-user (MU) multiple-input multiple-output (MIMO) mmWave network degraded by the inevitable residual additive transceiver hardware impairments (RATHIs) and channel aging. Given this setting, we derive the coverage probability and the area spectral efficiency (ASE), and we subsequently evaluate the impact of residual transceiver hardware impairments and channel aging on these metrics. Different path-loss laws for line-of-sight and non-line-of-sight are accounted for the analysis, which are among the distinguishing features of mmWave systems. Among the findings, we show that the RATHIs have a meaningful impact at the high-signal-to-noise-ratio regime, while the transmit additive distortion degrades further than the receive distortion the system performance. Moreover, serving fewer users proves to be preferable, and the more directive the mmWaves are, the higher the ASE becomes.
Predicting Macronutrient of Baby Food using Near-infrared Spectroscopy and Deep Learning Approach

—In Indonesia, malnutrition and overnutrition can still be found especially among children and toddlers who are supposed to get adequate nutrition. The cause of malnutrition is inadequate nutrition intake, both in terms of the quantity and quality of the food. Therefore, mothers need to know whether the food consumed by children has reached the specified nutrition intake recommendation. This research develops a system to predict macronutrient content in baby food using Near-infrared Spectroscopy (NIRS) to obtain the spectral profile of the food and Deep Learning approach such as Deep-belief network (DBN) and Convolutional Neural Network (CNN) to build the prediction model. We used instant-porridge scan data from SCiO to build the model. CNN managed to give the best performance with error for carbohydrate, protein and fat 11.70%, 26.14% and 28.72% respectively.
Screening $\Lambda$ with Energy-Momentum Log Gravity

Özgür Akarsu,1, ∗ John D. Barrow,2, † Charles V. R. Board,2, ‡ N. Merve Uzun,3, § and J. Alberto Vazquez4, ¶ 1Department of Physics, Istanbul Technical University, Maslak 34469 Istanbul, Turkey 2DAMTP, Centre for Mathematical Sciences, University of Cambridge, Wilberforce Road, Cambridge CB3 0WA, U.K. 3Department of Physics, Boğaziçi University, Bebek 34342 Istanbul, Turkey. 4Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México, Apdo. Postal 48-3, 62251 Cuernavaca, Morelos, México (Dated: March 28, 2019)
Significance of speech production errors on cross-linguistic processing in Sepedi-English individuals with bilingual aphasia: a case series analysis

ABSTRACT Background: Bilingual aphasia forms a significant part of speech-language pathologists’ (SLP) caseload, globally, and specifically in South Africa. Few tools supporting clinical decision-making are available due to limited understanding of typical and disordered cross-linguistic processing (how the languages interact). Speech errors may provide insight about “hidden” bilingual mechanisms. Objectives: To determine what speech errors can impart about cross-linguistic processing, as well as, associated language and impairment variables in Sepedi-English individuals with aphasia. Method: The case series included six participants, purposively selected from three rehabilitation sites in South Africa. Detailed language and clinical profiles were obtained. Participants performed a confrontation naming task in their most dominant (MDL) and less dominant language (LDL). Responses were audio recorded, transcribed, and analyzed for overall accuracy and error type in MDL and LDL; verified by a Sepedi-speaking linguist and a qualified SLP. Results: (1) No statistically significant differences in MDL-LDL naming accuracy were found, supporting recent literature of simultaneous inter-activation of both languages and shared word retrieval mechanisms. All types of speech errors occurred, and semantic errors were produced most frequently and consistently in each participant’s MDL and LDL. (2) Language proficiency, language recovery patterns, and aphasia type (Broca’s and Anomic) and severity (mild and/or moderate) appeared to be more strongly linked to cross-linguistic processing than Sepedi-English linguistic differences and age of acquisition of both languages. Conclusions: Participants with bilingual aphasia may use typical cross-linguistic and word retrieval mechanisms, concurring with current theories of bilingualism. Findings are preliminary, warranting investigations of other language tasks, modalities, pairs, and related variables.