Miracle-dz/UniFAR-FTUs huggingface dataset:
Validation of Biomarkers for Active Surveillance of Prostate Cancer

Prostate cancer is the second leading cause of cancer-related deaths among men in the United States and the most commonly diagnosed non-cutaneous form of cancer in this population. Treatment of early-stage prostate cancer is controversial, particularly when tumors are detected via prostate-specific antigen (PSA) screening. Use of this biomarker has certainly increased prostate cancer detection. Yet, it has also led to the over-diagnosis of low-risk forms of this heterogeneous disease. In a large majority of cases, new diagnoses of prostate cancer are aggressively treated, though there is evidence that many of the diagnosed cancers are low risk and may never become clinically evident during a patient's lifetime even if he is never treated (Wilt et al., 2012).
Prevalence and associate risk factors of upper limb disorders in school teachers in Semnan (Iran)

Introduction: Upper limb disorder is a common musculoskeletal deficiency in some occupational groups. In spite of its frequency in occupational groups, the study of prevalence and risk factors for upper limb disorder (ULD) in Iranian teachers is limited. The aims of this study were to assess the prevalence and risk factors for ULD and to investigate the association of individual and occupational characteristics with the prevalence of ULD in school teachers in Semnan. Materials and Methods: This study was performed by a cross-sectional method. Regarding the inclusion and exclusion criteria, 586 teachers were randomly chosen from 22 primary and high schools in Semnan, Iran. Required data including personal and occupational characteristics, pain intensity, health status and the prevalence and risk factors of ULD were collected using different questionnaires. Results: The prevalence rates of ULD at the time of study, last month, last 6 months, annual, and lifetime were; 46.4%, 50.2%, 57.3%, 60%, and 62.6%, respectively. The prevalence of waist pain in teachers was more than shoulder and elbow pain. The prevalence of ULD was significantly associated with age, gender, and length of employment (P < 0.05 in all instances). Writing on board in class, working hours with computer, and incorrect posturing during teaching and correcting examination papers were the factors which raised the risk of occurrence of ULD in teachers, respectively (P=0.03). Conclusion: Prevalence of ULD in school teachers in Semnan was high. Factors such as age, gender, length of employment, and work-related activities developed significantly ULD in school teachers Keywords: Prevalence, Upper Extremity, Faculty, Risk Factor
Neuronal Mismatch along the Auditory Hierarchy in an Animal Model of Schizophrenia

In this thesis I present a compendium of three articles. I demonstrate that single neurons in the central auditory system exhibit prediction error responses that mimic those recorded in MMN studies. This funding support the hypothesis that single neurons along the auIn this thesis I present a compendium of three articles. I demonstrate that single neurons in the central auditory system exhibit prediction error responses that mimic those recorded in MMN studies. This funding support the hypothesis that single neurons along the auditory brain take their part in the computations of MMN and predictive activity in the brain. Moreover, these prediction error responses are organized in a hierarchical manner, consisten across species and awareness states. Similarly, my results agree with eeflkvidences showing that mismatch responses are dependent on NMDA receptor activity. All these results agree with the general predictive coding framework. Furthermore, I demonstrate that stimulus-specific adaptation at the single neuron level in the inferior colliculus are modulated by cannabinoids, adding evidences of cannabinoids neuromodulatory activity. ditory brain take their part in the computations of MMN and predictive activity in the brain. Moreover, these prediction error responses are organized in a hierarchical manner, consisten across species and awareness states. Similarly, my results agree with evidences showing that mismatch responses are dependent on NMDA receptor activity. All these results agree with the general predictive coding framework. Furthermore, I demonstrate that stimulus-specific adaptation at the single neuron level in the inferior colliculus are modulated by cannabinoids, adding evidences of cannabinoids neuromodulatory activity.
Human Health Risks Associated with Recreational Waters: Preliminary Approach of Integrating Quantitative Microbial Risk Assessment with Microbial Source Tracking

Gastrointestinal (GI) illness risks associated with exposure to waters impacted by human and nonhuman fecal sources were estimated using quantitative microbial risk assessment (QMRA). Microbial source tracking (MST) results had identified Escherichia coli (E. coli) contributors to the waterbody as human and unidentified (10%), cattle and domestic animals (25%), and wildlife (65%) in a rural watershed. The illness risks associated with ingestion during recreation were calculated by assigning reference pathogens for each contributing source and using pathogen dose–response relationships. The risk of GI illness was calculated for a specific sampling site with a geometric mean of E. coli of 163 colony forming units (cfu) 100 mL−1, and the recreational standard of E. coli, 126 cfu 100 mL−1. While the most frequent sources of fecal indicator bacteria at the sampling site were nonhuman, the risk of illness from norovirus, the reference pathogen representing human waste, contributed the greatest risk to human health. This study serves as a preliminary review regarding the potential for incorporating results from library-dependent MST to inform a QMRA for recreational waters. The simulations indicated that identifying the sources contributing to the bacterial impairment is critical to estimate the human health risk associated with recreation in a waterbody.
Chirurgie cardiaque sous circulation extra-corporelle et ses biomarqueurs : rôle du Growth / Différentiation Factor 15 (GDF 15) : études cliniques

La circulation extracorporelle compte parmi les progres techniques majeurs associes a la chirurgie cardiaque. Elle constitue aussi l’une des causes de complications principales car responsable d’une reponse inflammatoire generalisee qui resulte de la conjugaison des effets du stress oxydant et des cytokines liberes, contribuerait a la dysfonction multi-organe aboutissant aux complications myocardiques et renales survenant au cours des periodes per- et postoperatoires. La premiere partie de notre travail avait pour objectif d’explorer l’evolution des taux circulants du GDF-15, cytokine associee au stress oxydant et a l’inflammation, dans ce contexte de chirurgie cardiaque. Notre etude prospective a demontre pour la premiere fois que cette procedure est accompagnee de l’augmentation du GDF-15 dont les taux plasmatiques sont associes aux lesions postoperatoires cardiaques et renales.L’evaluation du risque operatoire repose sur un ensemble de scores dont le calcul est base essentiellement sur des caracteristiques cliniques. Ces scores presentent toutefois un certaines limitations. Chez les patients « medicaux » atteints de pathologies cardiovasculaires la stratification du risque est definie en associant des caracteristiques cliniques a l’evaluation des taux circulants de biomarqueurs. L’objectif de cette seconde partie a donc ete de mettre en evidence le pouvoir predictif du GDF-15 en tant que biomarqueur circulant dans la survenue de complications renales au cours de la chirurgie cardiaque sous CEC. Nous avons mis en evidence que les patients presentant des taux preoperatoires eleves de GDF-15 sont a risque de developper une insuffisance renale aigue postoperatoire.
Influência da Ventilação Natural na Sensação Térmica do Usuário em Ambiente Educacional

The increase in energy consumption is a theme that has aroused a wide concern of many researchers and authorities in almost all the world, and one of the factors that influence this consumption is the increasing in the use of artificial acclimatization systems, mainly air conditioners. Thus, the search for buildings that demand less energy has become increasingly common in the last years. Therefore, the use of natural ventilation stands out as an important strategy to promote thermal comfort and indoor air quality, with minimal or no energy consumption at all. The research evaluated the hygrothermal conditions and the air movement acceptability as a comfort strategy in a naturally ventilated educational environment in the city of Vitória / ES, which climate is classified as tropical hot and humid. It also verified the influence of the ventilation on the comfort of the users and the impact of prior exposure of users to conditioned environments in their thermal preference. For this, measurements of the internal environmental variables (air temperature, globe temperature, relative air humidity and air velocity) were carried out while the occupants answered the questionnaire regarding thermal sensations and air velocity. In this way, the associations between the values of the environmental variables and the sensations reported by the occupants were obtained. The results are presented in the form of tables and graphs by relating the internal microclimatic variables with the occupants' responses. The results demonstrated that the highest values of thermal neutrality were concentrated with the operating temperature between 26 °C and 28 °C. The occupants, for the most part, accepted air velocities above 1m/s, mainly from 26oC, and these were fundamental in reducing thermal discomfort by heat. There were differences between the thermal preference of occupants with and without the routine exposure to air conditioned environments. Regarding the type of acclimatization in the environment studied, 53.6% of users answered that they prefer natural ventilation, while 26.8% prefer natural ventilation and fans and 19.6% opted for air conditioning.
Identity Research That Engages Contextual Forces to Reduce Socioeconomic Disparities in Education

A growing amount of psychological research contributes to the understanding of complex social issues, including socioeconomic disparities in academic outcomes. At a basic level, several studies demonstrate the ways that socioeconomic resources and opportunities shape the identities of students during adolescence and young adulthood, particularly emphasizing how they imagine their lives in the future. These future identities, in turn, affect how students engage in school tasks and respond to academic difficulty. The implications of these basic insights connecting socioeconomic resources, identity, and academic outcomes are most meaningful when considered within various levels of social-contextual influence that surround students. A collection of studies demonstrates how peers, parents, teachers, and educational institutions as a whole can be targeted and leveraged to support student identities and outcomes. This deepened engagement with various levels of context can complement and advance the existing emphasis on individual-level intervention as a strategy to contribute to the progress of psychological science toward greater influence and significance.
Tarso-crural Arthrodesis: Complications and Recommendations

A retrospective study of tarso-crural arthrodesis was undertaken to identify factors important for a successful result. Data was collected on 16 dogs surgically treated by tarso-crural arthrodesis (21 attempts: 18 primary and three secondary). Animals were grouped as to stabilization type: internal fixation, external skeletal fixation, or a combination of the two methods. Complications and success rates were analyzed for each group. Arthrodesis failures, irrespective of the method used, were a result of insufficient fixation and a lack or premature removal, of secondary support fixation or coaptation. Seven technical recommendations are made to help minimize complications and increase tarso- crural arthrodesis success rates.
Simulation of 3-D Electromagnetic Scattering and Inverse Scattering by Arbitrary Anisotropic Dielectric Objects Embedded in Layered Arbitrary Anisotropic Media

This communication studies 3-D electromagnetic (EM) scattering and inverse scattering of arbitrary anisotropic dielectric objects embedded in multilayered media. Different from previous work, the scatterer is not only arbitrary anisotropic, but also the arbitrary anisotropy of the layered background media is formed by rotation of the principal axes of uniaxial media. In addition, the scatterers are allowed to be placed across layer boundaries. The forward model is formulated by the electric field integral equation (EFIE), solved by the biconjugate gradient stabilized (BCGS) method, and accelerated by the fast Fourier transform (FFT). The time complexity is analyzed for the BCGS-FFT applied to layered arbitrary anisotropic media. In the inversion model, the variational Born iterative method (VBIM) is employed to reconstruct the arbitrary anisotropic profiles of both the permittivity and conductivity. Numerical simulations are performed to verify the feasibility and antinoise ability of the forward and inverse solvers in the circumstance of layered arbitrary anisotropic background media.
Challenges and use of virtual tools in teamwork

Purpose of the article There have been many studies focusing on teamwork. However, the digital transformation has caused new challenges in this field. Thus, the aim of the article is to provide insight into the most significant challenges in virtual teamwork and to identify the used and known virtual tools. Methodology/methods This study adopted a quantitative approach by means of questionnaire administered online. The final sample consisted of 622 respondents from two universities from Poland and Romania. The survey was conducted on January 2019. Students from several classes from the bachelor and the master programs of all faculties of both universities were approached to respond to a survey. Scientific aim The aim of the survey was to diagnose the students’ experience in virtual teamwork, their challenges of working in this type of teams, and knowing and using of tools for virtual teamwork. Findings The research results shows that almost half of the students (48,1 percent) have experience in virtual teamwork. Their experience is mainly regarding with preparing a project or a presentation for classes. However, the most used tools are these which are the most popular: messengers, mobile phone, social media like Facebook, e-mail and tool for creating folders and holding files like Google drive. Thus, one of the dimensions of challenges of work in virtual teams is insufficient knowledge of IT tools by team members and technology difficulties (eg. software, computer, internet access). Conclusions In the context of growing needs in this area, it seems important to support to acquire teamwork skills. It seems that the students learn to use virtual tools by the way doing of something for classes. Thus, the classes should teach students how to use of virtual tools to a greater extent, especially that some of the tools are well known but not used. Organizations might offer internships to enable students to develop skills in using specific virtual tools.
Growth and Haemato-Biochemical Response in Lambs in Relation to Supplementary Feeding of Ewes in Late Pregnancy

A study was undertaken to elucidate the effect of concentrate supplementation (eight weeks before the expected date of lambing) to native ewes in coastal Odisha on lamb growth and haemato-biochemical profile. Forty pregnant ewes (12 months old) were randomly distributed into two groups (T-1 and T-2). Ewes of T-1 were maintained on grazing only while ewes of T-2 were supplemented with concentrate mixture @ 200 g/sheep/day along with grazing. Significantly (P<0.01) higher birth weight and growth was observed in T-2 group lambs. The lambs in T-2 showed significantly (P<0.05) higher haemoglobin, packed cell volume, blood glucose, total protein and globulin values in the pre-weaning period than those in T-1. It was concluded that pre-partum concentrate feeding @ 200 g/day/ewe to the pregnant ewe improved birth weight and growth rate of lambs.
Parametric Analysis and Optimization of Rotary Ultrasonic Machining of Zirconia (ZrO2) Ceramics

Micro-channels are considered as the essential part of several medical applications such as microfluidics devices, lab on a chip, microbiology, etc. In most applications, fluid flow is required to pass through certain microchannels. The fluid flow characteristics such as flow rate and fluid dynamics are mainly accomplished based on the surface quality and dimensional accuracy of the microchannels. In this study, the microchannels are fabricated on zirconium oxide (ZrO2) using rotary ultrasonic machining (RUM). A full factorial design of experiments is employed in order to detect the influences of key input parameters of RUM including cutting speed (S), feed rate (FR), depth of cut (DOC), frequency (F) and amplitude (A) on surface roughness (Ra), edge chipping (EC), depth error (DE) and width error (WE) of the milled microchannels. Multi-objective genetic algorithm (MOGA) was employed to determine the optimal parametric conditions for minimizing the values of Ra, EC, DE, and WE of the fabricated microchannels. Results revealed that the minimum value of Ra = 0.26 μm, EC = 10.1 μm, DE = 4.2% and WE = 7.2% can be accomplished through the multi-objective optimization at higher levels of frequency and amplitude and lower levels of feed rate, depth of cut and cutting speed.
¿Quién es el Dios de los jóvenes? Una aproximación a la imagen de Dios en estudiantes de enseñanza media

The goal of this research paper is to analyse the religious understanding of secondary school students from Santiago, within the academic context, by identifying: the representation of God students have built and the influence that main players such as family members, pairs, school, teachers, Religion teachers, among others, may have had in the concept of God students have constructed. For that purpose, a survey has been designed as research instrument. The latter has been applied to 26 schools across the Gran Santiago district. A final sample of 1299 case studies has been retrieved. The research has taken into consideration the distribution of the Chilean educational system. That is to say, data has been retrieved considering percentages from private, subsidized and State-run schools, as well as Religious and laic schools. In a first stage of results, data about the religious understanding and the concept of God students have constructed, considering whether they come from Catholic or laic schools, has been presented.
Screening of Optimized Carrot Pulp Concentration for Development of Vitamin a Fortified Lassi

In the present investigation, fortification of lassi with carrot pulp was aimed to enrich the product with vitamin A. The physico-chemical composition of end product was observed as fat content 2.48-2.37, acidity 0.42-0.51 (as per cent lactic acid), total sugars 13.64-16.21 and TSS 14.00 to 15.43 per cent, respectively. The fat content of lassi samples decreased with increase in level of carrot pulp while parameters like acidity, viscosity, fiber content, total sugars, and TSS increased with increase in the level carrot pulp. The overall acceptability for sensory score for lassi prepared using 10 per cent carrot pulp was highest i.e. liked very much. The mean lactic acid count count was found to increase with increasing pulp from 8.50 to 8.68 log cfu/ml. However, the lassi samples were free from yeast & mold and coliforms.
Algorithm Selection as Recommendation: From Collaborative Filtering to Dyad Ranking

Problem classes such as integer optimization, SAT, and classification can be tackled by a large variety of algorithms, the performance of which may differ depending on the concrete problem instance at hand. In fact, theoretical arguments even exclude the existence of a single algorithm that is superior to all other algorithms on all instances of a problem class [17]. Hence, compared to using the algorithm that is best on average across an entire class of problem instances, called the single best solver (SBS), selecting a suitable algorithm for each instance separately should result in an increased overall performance.
Supervised learning with convolutional neural networks for hyperspectral visualization

ABSTRACT The Visualization for hyperspectral images is demanded by the ground processing system for quick view and information survey. Previous methods using band selection or dimension reduction fail to produce stable details and good colours as reasonable as corresponding multispectral images. In this paper, a mixed strategy is proposed which utilizes multi-band selection and supervised learning to integrate natural spatial details within hyperspectral bands for visualization. In the training stage, multispectral images are introduced as the reference, which are targeted by convolutional neural networks modelling the conversion from hyperspectral bands to multispectral bands. In order to preserve the colour, the hyperspectral band numbers are recorded for those with high correlation to the reference images, which are put into the network for dimension reduction. The proposed method is tested for the EO-1 Hyperion hyperspectral images with LandSat-8 images as the benchmark. The results are compared with five state-of-the-art algorithms. The comparison results show that the present method has good performance in maintaining both structures and colours.
Grau de dependência e funcionalidade familiar do idoso

Objetivou-se avaliar o grau de dependência do idoso e sua relação com a funcionalidade familiar. Estudo exploratório, descritivo de abordagem quantitativa, realizado com 37 idosos dependentes. Verificou-se que 81,1% deles são idosos dependentes; e 51,4% apresentam uma família altamente funcional. Evidenciou-se que a maioria desses idosos apresentavam uma certa dependência e que, apesar de não ter sido identificada uma relação direta entre as variáveis estudadas, destacou-se a importância de bem compreendê-las.
The challenges of human papillomavirus and cervical cancer therapy and control in Nigeria: A review

With the changing paradigm in disease trends, Nigeria may be faced with serious challenges in terms of healthcare and disease management. Cervical cancer, which is one of the cancers that is vaccine preventable, remain the most frequently reported and the leading cause of mortality from cancer in Nigeria. More than 36.59 million women are at risk and 26 die of the disease on daily basis. The country is currently ranked the worse place to be a woman with cancer in Africa, yet there is nothing to write home about in terms of preparedness. Every year huge amount of money is released but little or nothing gets done. There is urgent need for immediate action, especially with the advent of the three promising prophylactic vaccines, to be more pro-active, in controlling the menace of cervical cancer in the country. Cervical cancer should be given same priority as HIV/AIDs, Tuberculosis, Malaria and Childhood immunizations. Key words : Cervical cancer, Challenges, Control, Human papillomavirus, Nigeria, Therapy.