Miracle-dz/UniFAR-FTUs huggingface dataset:
A HYBRID INTELLIGENT MODEL BASED ON EVOLUTIONARY FUZZY CLUSTERING AND SYNDICATE NEURAL NETWORKS

In this article, a new hybrid intelligent model comprising a cluster allocation and adaptation component is developed for solving classification and pattern recognition problems. Its computation ability has been verified through various benchmark problems and biometric applications. The proposed model consists of two components: cluster distribution and adaptation. In the first module, mean patterns are distributed into the number of clusters based on the evolutionary fuzzy clustering, which is the basis for network structure selection in next module. In the second module, training and subsequent generalization is performed by the syndicate neural networks (SNN). The number of SNNs required in the second module will be same as the number of clusters. Whereas each network contains as many output neurons as the maximum number of members assigned to each cluster. The proposed novel fusion of evolutionary fuzzy clustering with a neural network yields superior performance in classification and pattern recognition problems. Performance evaluation has been carried out over a wide spectrum of benchmark problems and real-life biometric recognition problems with noise and occlusion. Experimental results demonstrate the efficacy of the methodology over existing ones.
Biodegradation of Petroleum Hydrocarbons by Two Pseudomonas aeruginosa Strains with Different Uptake Modes

The uptake modes of alkanes by two strains (Pseudomonas aeruginosa S and Pseudomonas aeruginosa Y) were compared in this article. It was found that the strain of P. aeruginosa S showed low cell surface hydrophobicity and the surface tension of the broth decreased when the strain was cultivated on alkanes. On the contrary, P. aeruginosa Y showed higher cell surface hydrophobicity and the change in surface tension was not significant. This suggests that P. aeruginosa Y accessed hydrocarbon droplets by direct contact mode, while P. aeruginosa S engaged hydrocarbon droplets by biosurfactant-medium mode. The biodegradation of petroleum hydrocarbons by the two strains was also investigated. The results showed that irrespective of the substrate utilized: liquid hydrocarbons, solid hydrocarbons or crude oil in contaminated soil, the degradation by P. aeruginosa S was faster than that by P. aeruginosa Y. It was also deduced that the produced biosurfactant is advantageous in improving the biodegradation process.
Morphological studies on the culture of kidney epithelial cells in a fiber-in-fiber bioreactor design with hollow fiber membranes.

A hollow fiber-in-fiber-based bioreactor system was tested for the applicability to host kidney epithelial cells as a model system for a bioartificial kidney. Hollow fibers were prepared from polyacrylonitrile (PAN), polysulfone-polyvinylpyrollidinone (PVP) blend (PSU) and poly(acrylonitrile-N-vinylpyrollidinone) copolymer P(AN-NVP). Hollow fibers with smaller and larger diameters were prepared so that the smaller fitted into the larger, with a distance of 50-100 microm in between. The following material combinations as outer and inner fiber were applied: PAN-PAN; PSU-PSU, PSU-P(AN-NVP). Madin-Darby kidney epithelial cells (MDCK) were seeded in the interfiber space and cultured for a period up to 14 days. Light, scanning, and transmission electron microscopy were used to follow the adhesion and growth of cells, and to characterize their morphology. As a result, we found that MDCK cells were able to grow in the interfiber space in mono- and multilayers without signs of systemic degeneration. Comparison of the different materials showed that PAN and P(AN-NVP) provided the best growth conditions, indicated by a tight attachment of cells on hollow fiber membrane, and subsequent proliferation and development of structural elements of normal epithelia, such as tight junctions and microvilli. In conclusion, the fiber-in-fiber design seems to be an interesting system for the construction of a bioartificial kidney.
Risk Taking in Adolescents With Attention Deficit Hyperactivity Disorder on a Probabilistic Choice Task

Abstract Risk taking is commonly attributed to individuals with attention deficit hyperactivity disorder (ADHD). This study investigated whether adolescents with ADHD would choose to take greater risks on a probabilistic task in which contingencies are explicitly presented. Adolescents with and without ADHD, aged 13 to 18 years, performed a modified version of the Cambridge Gambling Task. The subjects with ADHD risked smaller sums and chose the unfavorable outcomes more frequently than did the controls but had the same speed of decision and risk adjustment. The results indicate that their poor decisions were not due to impulsivity or insensitivity to the concept of probability and that increased risk taking is not always associated with ADHD. Moreover, in situations that do not demand learning of contingencies, ADHD may be associated with decreased, rather than increased, risk taking.
Antibiotic prescribing and antibiotic resistance in community practice: retrospective study, 1996-8

Data on the susceptibility to antibiotics of coliform organisms in routine urine samples taken by general practitioners for diagnosis of urinary tract infections were collected from the Bangor, Cardiff, and Rhyl Public Health Laboratories and the East Glamorgan, Prince Charles, and Wrexham Maelor Hospitals. Data on the prescribing practices of surgeries were obtained from the Welsh Prescription Pricing Service Rates of prescribing (the number of prescriptions/1000 patients per year) and resistance rates (which excluded multiple isolates of organisms with the same susceptibility from the same patient) were calculated for each surgery. The use of broad spectrum penicillin formulations without a β lactamase inhibitor (such as ampicillin and amoxicillin) was estimated by subtracting the number of prescriptions for co-amoxiclav from the total number of prescriptions for all other broad spectrum penicillins. We use the term amoxicillin below to refer to these broad spectrum penicillins without a β lactamase inhibitor. Resistance rates for surgeries which were based on fewer than 50 isolates were excluded, leaving data on about 30 000 isolates from 190 general practitioner surgeries serving about 1 200 000 patients. We sought to identify the effects of bias caused by the selective submission of urine samples by examining the relation between resistance rates and sampling (number of urine specimens/1000 registered patients) and the relation between positivity (number of coliform isolates/100 samples or 1000 registered patients) and prescribing or sampling. The use of antibiotics and rates of resistance to antibiotics varied between surgeries; the correlation between the prescribing of an antibiotic and resistance to the same antibiotic was often significant (table) The correlation was also significant between the use of amoxicillin and resistance to trimethoprim and vice versa. Combined resistance to ampicillin and trimethoprim occurred in 21% (6782/32 532) of isolates and was significantly associated with the use of both trimethoprim and amoxicillin (P<0.001). The correlation between the use of amoxicillin and resistance to trimethoprim and vice versa was lost when strains exhibiting combined resistance to both agents were removed from the analysis.
A technique for periorbital syringomas: intralesional radiofrequency ablation.

AIM To evaluate the efficacy of intralesional radiofrequency ablation in the treatment of periorbital syringomas. METHODS We tried the intralesional radiofrequency ablation for 64 patients with periorbital syringomas from 2007 to 2011. The operation was performed under 2.5 loupe magnifications. The handpiece was assembled with a needle electrode and connected to the radiofrequency ablation apparatus. The electrode was then inserted into the target lesions in dermis and delivering injury to the base of these tumors. Results were assessed clinically by comparing pre- and post-treatment photographs and patient satisfaction rates. RESULTS Clinical improvement increased with each subsequent treatment session. The percent of patients whose clinic improvement grade were≥3 after each session was respectively 71.9%(Session1), 83.3%(Session2), and 100%(Session3). The statistical results indicated the concordance of the clinical assessment and the satisfaction level of patients (kappa=0.78 of the session1; kappa=0.82 of the session2). The majority of patients had good or excellent cosmetic results. Postoperatively, there were no permanent side effects or recurrences. CONCLUSION As a new technique of minimally invasion, the intralesional radiofrequency ablation was found to be an effective, inexpensive, highly precise and safe way of treating periorbital syringomas.
Demagnetization analysis of ferrite magnet motor based on reluctance network analysis

This paper presents a method for demagnetization analysis of ferrite magnet motor based on reluctance network analysis (RNA). First, to verify the accuracy of the proposed method, the calculated results are compared to experimental results by using experimental model. Next, an RNA model of a surface permanent magnet (SPM) motor considering demagnetization of the rotor magnets is presented. Using the proposed RNA model, the torque of the SPM motor is compared between before and after demagnetization.
What is the use of transmitting knowledge if the individual ' s total development lags behind ? "

This paper is an expanded version of a talk given at a Generic Skills Workshop at the University of Wollongong, and was intended for academic staff from any discipline and general staff with an interest in teaching. The issues considered in the paper include the capacity of all to learn, the distinction between learning as understanding and learning as information, the interaction between the communication and content of ideas, the tension between perception and content in communication between persons, and the human functions of a love of learning. In teaching, the creation of a fear-free environment is emphasised, as is the use of analogy as a means of breaking out of one discipline and making connections with another, with mathematics and history being used as a possible example. Some of the issues raised are explored in more depth in the notes at the end of the paper, to which there are references in the main text. About the author. Rodney Nillsen studied literature, mathematics and science at the University of Tasmania. He proceeded to postgraduate study at The Flinders University of South Australia, studying mathematics under Igor Kluvánek and, through him, coming into contact with the European intellectual tradition. He held academic positions at the Royal University of Malta and the University College of Swansea, Wales. Upon returning to Australia, he took up a lecturing position at the University of Wollongong, where he continues to teach and conduct research in pure mathematics. At the University he is a member of Academic Senate and is the Chair of the Human Research Ethics Committee. He received a Doctor of Science degree from the University of Tasmania in 2000. His interests include literature, classical music and the enjoyment of nature. Ca n th e L o v e o f L e a rn in g b e T a u g h t? Ro d n ey Ni l l s e n Journal of University Teaching and Learning Practice – Vol 1/1, 1-9, 2004 2 ". What is the use of transmitting knowledge if the individual's total development lags behind? "
Linkage of Oxidative Stress and Mitochondrial Dysfunctions to Spontaneous Culture Degeneration in Aspergillus nidulans*

Filamentous fungi including mushrooms frequently and spontaneously degenerate during subsequent culture maintenance on artificial media, which shows the loss or reduction abilities of asexual sporulation, sexuality, fruiting, and production of secondary metabolites, thus leading to economic losses during mass production. To better understand the underlying mechanisms of fungal degeneration, the model fungus Aspergillus nidulans was employed in this study for comprehensive analyses. First, linkage of oxidative stress to culture degeneration was evident in A. nidulans. Taken together with the verifications of cell biology and biochemical data, a comparative mitochondrial proteome analysis revealed that, unlike the healthy wild type, a spontaneous fluffy sector culture of A. nidulans demonstrated the characteristics of mitochondrial dysfunctions. Relative to the wild type, the features of cytochrome c release, calcium overload and up-regulation of apoptosis inducing factors evident in sector mitochondria suggested a linkage of fungal degeneration to cell apoptosis. However, the sector culture could still be maintained for generations without the signs of growth arrest. Up-regulation of the heat shock protein chaperones, anti-apoptotic factors and DNA repair proteins in the sector could account for the compromise in cell death. The results of this study not only shed new lights on the mechanisms of spontaneous degeneration of fungal cultures but will also provide alternative biomarkers to monitor fungal culture degeneration.
Kocuria arsenatis sp. nov., an arsenic-resistant endophytic actinobacterium associated with Prosopis laegivata grown on high-arsenic-polluted mine tailing.

A Gram-stain-positive, aerobic, non-motile, coccoid, arsenic-resistant actinobacterial strain, designated CM1E1T, was isolated from the lateral root tissue of Prosopis laegivata grown on a mine tailing in San Luis Potosi, Mexico. Phylogenetic analysis based on 16S rRNA gene sequences revealed that strain CM1E1T was clustered closely with species of the genus Kocuria, and showed the highest sequence similarity of 98.7 % to Kocuria rhizophila TA68T. The DNA G+C content of strain CM1E1T was 74.5 mol% (Tm). The major fatty acids were anteiso-C15 : 0, anteiso-C17 : 0 and iso-C15 : 0. The peptidoglycan of the cell wall contained lysine and alanine. The major respiratory quinones were MK-7(H2) and MK-8(H2). On the basis of the phenotypic characterization, phylogenetic relationships and chemotaxonomic analyses, strain CM1E1T represents a novel species of the genus Kocuria, for which the name Kocuria arsenatis sp. nov. is proposed. The type strain is CM1E1T ( = CCBAU 101092T = HAMBI 3625T = LMG 28671T).
Perindopril for the treatment of hypertension

Introduction: Treatment of hypertension is fundamental for the prevention of cardiovascular events and mortality. This review focuses on the specific benefits of the ACE inhibitor perindopril. Areas covered: A systematic literature search is undertaken for supporting the pharmacological proprieties and clinical efficacy of perindopril in the treatment of hypertension. Good tissue penetration, strong affinity for ACE and a long duration of action support the dose-dependent blood pressure lowering efficacy. Perindopril in combination with amlodipine significantly reduced total and cardiovascular mortality as compared to atenolol/diuretic in large-scale clinical trials of hypertensive patients. A greater reduction in blood pressure variability, central blood pressure and specific vascular protective proprieties of perindopril (improvement in arterial stiffness and endothelial function) might explain these results. Cardiovascular prevention with perindopril, in combination with indapamide, has been also shown in the elderly and patients with diabetes, cardio- and cerebrovascular diseases. Expert opinion: Perindopril is effective and safe for blood pressure control with a dose-dependent effect. Combination therapy with indapamide or amlodipine reduces cardiovascular events and mortality in hypertensive patients. Pharmacological proprieties and results of clinical trials support the choice of perindopril as an appropriate treatment for hypertensive patients.
Craving for Alcohol and Drugs in Animals and Humans

Abstract Research studies indicate that sites and pathways for appetitive drive states, that are located in the limbic system, appear to be responsible for normal and pathological craving for alcohol and other addicting drugs. Pathological craving for alcohol and drugs in humans has been substantiated by animal studies, which have identified neurosubstrates and neurotransmitters associated with behavioral models of addiction. Repetitive administration of alcohol and drugs appears to affect hedonic homeo-stasis of the appetitive drives leading to the hedonic alleostasis where negative reinforcement exceeds positive returns despite continued drug use. Neuroimaging studies have concentrated on areas in the brain related to reward or reinforcement of alcohol/drug use, but the technique can be employed to find support for a neurosubstrate to distinguish normal craving or “liking” from pathological craving or “wanting” a drug. Identifying the neurobasis of “wanting” a drug long after not “liking it” is central to understanding pathological craving and loss of control over drug use in addiction in humans. Neuroimaging is currently the only method to directly visualize sites for craving in the brain in humans. Neuroimaging techniques will provide methods, which are not possible in animals, for studying addictive disease in humans.
Sialorrhea — Therapeutic Drug Options

OBJECTIVE: To review the efficacy and safety of various drug treatments for sialorrhea. Pharmacotherapy for drug-induced sialorrhea is not addressed. DATA SOURCES: Clinical studies were identified using PubMed (1966–October 2001). Key search terms included sialorrhea and drug therapy. DATA SYNTHESIS: Sialorrhea is a social and physical detriment to patients. Drug treatment, although not necessarily the treatment of choice for all patients, can offer some symptom relief. CONCLUSIONS: Literature has documented that benztropine, glycopyrrolate, and scopolamine can reduce the incidence of sialorrhea. Although the literature evaluating the therapeutic options has limitations (e.g., small sample size, inconsistent outcome measurements), glycopyrrolate may have an advantage over the other agents due to fewer adverse effects.
Curbing the growth of candida-A comparative in-vitro study

Endodontics is the least forgiving branch of dentistry in terms of success or failure. Therefore, re-treatment has become a significant part of today’s endodontic practice. There is a growing evidence showing the presence of fungi especially Candida albicans in root canals of obturated teeth in which endodontic treatment has failed. It has been demonstrated that Candida species are resistant to some medications used in endodontics. The aim of this study was to examine the invitro susceptibility of Candida albicans to materials used in endodontics such as mineral trioxide aggregate (MTA), Calcium hydroxide Ca(OH)2/camphorated paramonochlorophenol (CMCP) /glycerine and chlorhexidine (CHX). MTA and CHX are effective anti-fungal agents each with 67% anti fungal activity while Ca(OH)2/CMCP showed 33% anti-fungal activity.
An adaptive hybrid genetic algorithm for the three-matching problem

This paper presents a hybrid genetic algorithm (GA) with an adaptive application of genetic operators for solving the 3-matching problem (3MP), an NP-complete graph problem. In the 3MP, we search for the partition of a point set into minimal total cost triplets, where the cost of a triplet is the Euclidean length of the minimal spanning tree of the three points. The problem is a special case of grouping and facility location problems. One common problem with GA applied to hard combinatorial optimization, like the 3MP, is to incorporate problem-dependent local search operators into the GA efficiently in order to find high-quality solutions. Small instances of the problem can be solved exactly, but for large problems, we use local optimization. We introduce several general heuristic crossover and local hill-climbing operators, and apply adaptation to choose among them. Our GA combines these operators to form an effective problem solver. It is hybridized as it incorporates local search heuristics, and it is adaptive as the individual recombination/improvement operators are fired according to their online performance. Test results show that this approach gives approximately the same or even slightly better results than our previous, fine tuned GA without adaptation. It is better than a grouping GA for the partitioning considered. The adaptive combination of operators eliminates a large set of parameters, making the method more robust, and it presents a convenient way to build a hybrid problem solver.
Discovering geographic web services in search engines

Purpose – There is an open discussion in the geographic information community about the use of digital libraries or search engines for the discovery of resources. Some researchers suggest that search engines are a feasible alternative for searching geographic web services based on anecdotal evidence. The purpose of this study is to measure the performance of Bing (formerly Microsoft Live Search), Google and Yahoo! in searching standardised XML documents that describe, identify and locate geographic web services.Design/methodology/approach – The study performed an automated evaluation of three search engines using their application programming interfaces. The queries asked for XML documents describing geographic web services, and documents containing links to those documents. Relevant XML documents linked from the documents found in the search results were also included in the evaluation.Findings – The study reveals that the discovery of geographic web services in search engines does not require the use of.
Wave impedance matrices for cylindrically anisotropic radially inhomogeneous elastic solids

Impedance matrices are obtained for radially inhomogeneous structures using the Stroh-like system of six first-order differential equations for the time-harmonic displacement-traction 6-vector. Particular attention is paid to the newly identified solid-cylinder impedance matrix Z(r) appropriate to cylinders with material at r = 0, and its limiting value at that point, the solid-cylinder impedance matrix Z 0 . We show that Z o is a fundamental material property depending only on the elastic moduli and the azimuthal order n, that Z(r) is Hermitian and Z 0 is negative semi-definite. Explicit solutions for Z o are presented for monoclinic and higher material symmetry, and the special cases of n = 0 and 1 are treated in detail. Two methods are proposed for finding Z(r), one based on the Frobenius series solution and the other using a differential Riccati equation with Z o as initial value. The radiation impedance matrix is defined and shown to be non-Hermitian. These impedance matrices enable concise and efficient formulations of dispersion equations for wave guides, and solutions of scattering and related wave problems in cylinders.