Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative study and performance evaluation of multimedia scheduling in wireless networks

The mobile device usages in last decade grown enormously due to the variety of applications with video based contents. The video delivery through the internet is highly focused because of heavy demands from the mobile users. We take various techniques involved in video streaming in wireless networks. The different constraints and different methods have been studied with their merits and demerits and we proposing the optimal scheduling method which suits the heterogeneous wireless networks. The scheduling of video streaming has the number of research work for wired networks. We take the video streaming through the wireless networks which are highly demanded applications on mobile devices.
Ultra low power and high performance nanoelectronic devices

We are facing many challenges for future nanoelectronic devices in the next two decades dealing with scaling, power consumption and performance. This paper presents the most promising solutions for the end of the roadmap in the More Moore and Beyond-CMOS fields, including innovative materials such as ultra-thin Si-Ge-III-V/OI, 2D layers (phosphorene, transition-metal dichalcogenides, etc.), 1D semimetals, heterostructures using strained Si, Ge, III-V (InAs, GaSb, AlGaSb, graded layers, quantum wells, etc.), combined with advanced nanodevice architectures, especially ultimate Multigate NanoCMOS and Nanowire FETs, Tunnel FETs and FeFET, and Hybrid Nanoscale Transistors.
Money and Currency Market Implications of the Long Run Risk Models

Using postwar US and UK data, we study the implied interest rates and exchange rates in a simple Long Run Risk (LRR) model with two countries. When a closed economy is considered, emprical estimates show that, as in standard CCAPM models, the movements of the risk free rate implied by a baseline LRR model are entirely determined by the variations of the expected consumption growth. Nevertheless, differently from the standard CCAPM, the long run component of consumption growth is a key element to capture the counter-cyclical variations of the money market rates. Turning to an open economy setting, we find evidence that a baseline LRR model accounts for foreign exchange market movements.
Transcriptional Regulation of Mitotic Checkpoint Gene MAD1 by p53*

p53 regulates a number of genes through transcriptional activation and repression. p53-dependent mitotic checkpoint has been described, but the underlying mechanism is still obscure. Here we examined the effect of p53 on the expression of a human mitotic checkpoint protein, Mitosis Arrest Deficiency 1 (MAD1), in cultured human cells. The expression of MAD1 was reduced when the cells were overexpressing exogenously introduced wild-type p53. The same reduction was also observed when the cells were treated with anticancer agents 5-fluorouracil and cisplatin or were irradiated with UV. Consistently, MAD1 promoter activity diminished in a dose-dependent manner when induced by p53, indicating that p53 repressed MAD1 at a transcriptional level. Intriguingly, several tumor hot spot mutations in p53 (V143A, R175H, R248W, and R273H) did not abolish the ability of p53 to repress MAD1 expression. By serial truncation of the MAD1 promoter, we confined the p53-responsive element to a 38-bp region that represents a novel sequence distinct from the known p53 consensus binding site. Trichostatin A, a histone deacetylase inhibitor, relieved the p53 transrepression activity on MAD1. Chromatin immunoprecipitation assay revealed that p53, histone deacetylase 1, and co-repressor mSin3a associated with the MAD1 promoter in vivo. Taken together, our findings suggest a regulatory mechanism for the mitotic checkpoint in which MAD1 is inhibited by p53.
Did Medicaid expansions for pregnant women crowd out private coverage?

This paper documents the changing picture of health insurance coverage for pregnant women in the four-year period following Medicaid expansion and assesses the extent to which the crowding-out phenomenon may have influenced the observed trends. The report documents the distribution of insurance coverage for pregnant women in the post-expansion period and describes demographic characteristics of women covered under Medicaid. It examines the rate at which Medicaid-eligible women enroll in the program and addresses the crowding-out issue by comparing the trend in employer-sponsored coverage among poor and near-poor pregnant women with those among nonpregnant women and men of similar ages and incomes.
An architecture for 1-bit localized compressive sensing with applications to EEG

Compressed sensing exploits special signal features to extract its information content with a smaller amount of samples with respect to acquisition based on Nyquist theorem. While many theoretical results have proved the capabilities of this new paradigm, hardware implementations are still far from being practical. Here, we present a new architecture of analog to information converter that produces 1-bit compressive measurements. The performance of the architecture can be boosted if the signal to acquire features, beyond the classically required sparsity, also some sort of localization of its energy. The effectiveness of the architecture and of its enhancement is shown in the measurement of EEG, that presents a non-uniform spectral profile.
“There’s a Pain App for That”: Review of Patient-targeted Smartphone Applications for Pain Management

Objectives:There are a growing number of pain self-management applications (apps) available for users to download on personal smartphones. The purpose of this study was to critically appraise the content and self-management functionality of currently available pain apps. Methods:An electronic search was conducted between May and June 2014 of the official stores for the 4 major operating systems. Two authors independently identified patient-focused apps with a stated goal of pain management. Discrepancies regarding selection were resolved through discussion with a third party. Metadata from all included apps were abstracted into a standard form. The content and functionality of each app as it pertained to pain self-management was rated. Results:A total of 279 apps met the inclusion criteria. Pain self-care skill support was the most common self-management function (77.4%). Apps also purported providing patients with the ability to engage in pain education (45.9%), self-monitoring (19%), social support (3.6%), and goal-setting (0.72%). No apps were comprehensive in terms of pain self-management, with the majority of apps including only a single self-management function (58.5%). In addition, only 8.2% of apps included a health care professional in their development, not a single app provided a theoretical rationale, and only 1 app underwent scientific evaluation. Discussion:Currently available pain self-management apps for patients are simplistic, lack the involvement of health care professionals in their development, and have not been rigorously tested for effectiveness on pain-related health outcomes. There is a need to develop and test theoretically and evidence-based apps to better support patients with accessible pain care self-management.
Compact reflectarray antenna element using split ring resonator

This paper presents a compact reflectarray element using split ring resonators (SRRs) for small size and high gain reflectarray design. The proposed element is constructed of dual concentric split rings and a metal line on different layers. Several design parameters of the unit cell are studied for obtaining better phase response. The proposed unit cell achieves a good phase response of 700 degrees at X-band. The unit cell size is 14 mm × 14 mm (0.36 λ0 × 0.36 λ0). Due to the small unit cell size, the reflectarray with the proposed element can be expected to achieve high gain.
Mouse models of laminopathies

The A‐ and B‐type lamins are nuclear intermediate filament proteins in eukaryotic cells with a broad range of functions, including the organization of nuclear architecture and interaction with proteins in many cellular functions. Over 180 disease‐causing mutations, termed ‘laminopathies,’ have been mapped throughout LMNA, the gene for A‐type lamins in humans. Laminopathies can range from muscular dystrophies, cardiomyopathy, to Hutchinson–Gilford progeria syndrome. A number of mouse lines carrying some of the same mutations as those resulting in human diseases have been established. These LMNA‐related mouse models have provided valuable insights into the functions of lamin A biogenesis and the roles of individual A‐type lamins during tissue development. This review groups these LMNA‐related mouse models into three categories: null mutants, point mutants, and progeroid mutants. We compare their phenotypes and discuss their potential implications in laminopathies and aging.
Social Media and Diabetes: Can Facebook and Skype Improve Glucose Control in Patients With Type 1 Diabetes on Pump Therapy? One-Year Experience

Health care providers are faced with enormous numbers of patients and visits due to the increase in diabetes prevalence (1). As the world is changing, traditional health care services should be adapted for the new era of technology and Internet. Patients use Internet to seek, meet, and interact with a community of patients with similar problems; to share clinical information; and to provide and receive support (2,3). Facebook, with over 1.2 billion registered users worldwide, (4) has specific groups for disease information. The Facebook group “Diabetes Macedonia” was formed in 2008. It is a closed group that helps patients to share diabetes information and experience. The enormous growth of new users (1,430 patients, family members, and others by September 2014) led to the development of a structured platform by health …
La distribución del ingreso en Argentina, 1974-2000

En el ultimo cuarto de siglo,en Argentina la distribucion del ingreso empeoro persistentemente. El articulo utiliza el analisis de microsimulacion para descomponer el impacto que ejercieron los cambios laborales sobre la distribucion del ingreso familiar.El deterioro se produjo,en los anos setenta,por la reduccion real de las remuneraciones y su dispersion relativa; en los ochenta,a traves del creciente desempleo por sucesivas crisis; en los noventa,bajo el nuevo orden economico, como resultado del desempleo generado por la reestructuracion productiva y el aumento de la participacion,y en la ultima fase, por una mayor desigualdad en las remuneraciones.Se concluye que el nuevo estilo de funcionamiento de la economia determina, mas alla de la apreciacion cambiaria y del ulterior colapso del regimen macroeconomico,una menor elasticidad del empleo con respecto al crecimiento ? con el consiguiente desempleo estructural ? y mayores diferencias de salario por niveles de calificacion.
Flt3-mediated signaling in human acute myelogenous leukemia (AML) blasts: a functional characterization of Flt3-ligand effects in AML cell populations with and without genetic Flt3 abnormalities.

BACKGROUND AND OBJECTIVES Intracellular signaling initiated via Flt3 seems important in both leukemogenesis and chemosensitivity in acute myelogenous leukemia (AML). Flt3 is activated by binding of its natural Flt3-ligand (Flt3-L), but Flt3 genes with internal tandem duplications (Flt3-ITD) or Asp(D)-835 point mutations encode molecules with constitutive activation. The aim of this study was to compare functional effects of exogenous Flt3-L on AML blast populations with and without genetic Flt3 abnormalities. DESIGN AND METHODS Native AML blasts were derived from 64 consecutive patients with high blast counts in peripheral blood, and in vitro models were used to characterize the Flt3-L effects. RESULTS The Flt3 protein levels showed a similar wide variation between AML blast populations with and without genetic Flt3 abnormalities. Flt3-L was an autocrine growth factor only for 2 patients. Flt3-ITD+ AML cells had lower responsiveness to exogenous cytokines than cell populations without Flt3 abnormalities, but exogenous Flt3-L increased blast proliferation both for patients without Flt3 abnormalities and patients with Flt3-ITD as well as D835 mutations. This enhancement was observed even in the presence of other exogenous cytokines and included clonogenic AML progenitors. Flt3-L inhibited proliferation only for 1 patient, but had divergent effects on AML blast cytokine release. Flt3-L affected AML blast differentiation (inhibition of erythroid colonies, increased neutrophil granulation) only in a minority of patients, whereas it had an anti-apoptotic effect for a larger subset of patients. INTERPRETATION AND CONCLUSIONS Intracellular signaling initiated by Flt3 ligation modulates the functional phenotype for native human AML blasts both with and without genetic Flt3 abnormalities.
Embedded NAND flash file system for mobile multimedia devices

In this work, we present a novel mobile multimedia file system, MNFS, which is specifically designed for NAND flash memory. Our design specifically addresses the needs of devices such as MP3 players, personal media players (PMPs), digital camcorders, etc. The file system has three novel features important in mobile multimedia applications: (1) predictable and uniform write latency, (2) quick file system mount, and (3) a small memory footprint. We implemented the proto-type file system on an embedded platform. In our experiments, MNFS exhibits uniform I/O latency for sequential write operation. It is mountable within 0.2 seconds and available with only 34 Kbytes of heap memory for a 128 Mbytes volume. The mounting time is 30 times faster compared to that of YAFFS, which is a well known file system for NAND flash memory, and the heap memory usage is only 5% of the YAFFS usage.
Contribution of Innate Cortical Mechanisms to the Maturation of Orientation Selectivity in Parvalbumin Interneurons

The maturation of cortical parvalbumin-positive (PV) interneurons depends on the interaction of innate and experience-dependent factors. Dark-rearing experiments suggest that visual experience determines when broad orientation selectivity emerges in visual cortical PV interneurons. Here, using neural transplantation and in vivo calcium imaging of mouse visual cortex, we investigated whether innate mechanisms contribute to the maturation of orientation selectivity in PV interneurons. First, we confirmed earlier findings showing that broad orientation selectivity emerges in PV interneurons by 2 weeks after vision onset, 35 d after these cells are born. Next, we assessed the functional development of transplanted PV (tPV) interneurons. Surprisingly, 25 d after transplantation (DAT) and 2 weeks after vision onset, we found that tPV interneurons have not developed broad orientation selectivity. By 35 DAT, however, broad orientation selectivity emerges in tPV interneurons. Transplantation does not alter orientation selectivity in host interneurons, suggesting that the maturation of tPV interneurons occurs independently from their endogenous counterparts. Together, these results challenge the notion that the onset of vision solely determines when PV interneurons become broadly tuned. Our results reveal that an innate cortical mechanism contributes to the emergence of broad orientation selectivity in PV interneurons.
Reactive Oxygen Species Generation and Use of Antioxidants during In Vitro Maturation of Oocytes

In vitro maturation (IVM) is emerging as a popular technology at the forefront of fertility treatment and preservation. However, standard in vitro culture (IVC) conditions usually increase reactive oxygen species (ROS), which have been implicated as one of the major causes for reduced embryonic development. It is well-known that higher than physiological levels of ROS trigger granulosa cell apoptosis and thereby reduce the transfer of nutrients and survival factors to oocytes, which leads to apoptosis. ROS are neutralized by an elaborate defense system that consists of enzymatic and non-enzymatic antioxidants. The balance between ROS levels and antioxidants within IVM media are important for maintenance of oocytes that develop to the blastocyst stage. The effects of antioxidant supplementation of IVM media have been studied in various mammalian species. Therefore, this article reviews and summarizes the effects of ROS on oocyte quality and the use of antioxidant supplementations for IVM, in addition to its effects on maturation rates and further embryo development.
Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals

The success of long-term electrophysiological recordings often depends on the quality of the implantation surgery. Here we provide useful information for surgeons who are learning the process of implanting electrode systems. We demonstrate the implantation procedure of both a penetrating and a surface electrode. The surgical process is described from start to finish, including detailed descriptions of each step throughout the procedure. It should also be noted that this video guide is focused towards procedures conducted in rodent models and other small animal models. Modifications of the described procedures are feasible for other animal models.
Molecular Simulations on Interfacial Sliding of Carbon Nanotube Reinforced Alumina Composites

© 2012 Li et al., licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Molecular Simulations on Interfacial Sliding of Carbon Nanotube Reinforced Alumina Composites
Preschooler Feeding Practices and Beliefs: Differences Among Spanish‐ and English‐speaking WIC Clients

This study explored preschooler feeding practices and beliefs among Spanish- and English-speaking WIC participants in Texas. The Preschooler Feeding Questionnaire examined 9 dimensions of the parent–child feeding interaction among 235 caregivers. Results from ANOVA and post hoc analyses demonstrated significant differences in reported preschooler feeding practices and beliefs among Spanish-speaking Hispanics in comparison with English-speaking Hispanics and non-Hispanics. No significant differences were found between English-speaking Hispanics and non-Hispanics. Results indicated that acculturation may impact behaviors apart from ethnicity. Nutrition professionals should understand and acknowledge the cultural context of the parent–child feeding interaction when developing programs.
Modified weighted bit flipping algorithm based on intrinsic information for ldpc codes

This paper proposes a modified bit flipping algorithm and its weighted variants based on reliability derived from intrinsic information. Compared to other existing algorithms where extrinsic information based reliability was used in the flipping function, here intrinsic information based reliability is also equally considered. This algorithm only uses additions and subtractions to modify reliability as compared to other reliability based BF algorithms, which use multiplications and divisions. Hence, it offers good performance with a minimal increase in computational complexity.
High frequency of skewed X-chromosome inactivation in females with autoimmune thyroid disease: a possible explanation for the female predisposition to thyroid autoimmunity.

CONTEXT Autoimmune thyroid diseases (AITD) comprise Graves' disease (GD) and Hashimoto's thyroiditis (HT). They are characterized by loss of immunological self-tolerance and female preponderance. Theoretically, X chromosome inactivation (XCI) and resultant tissue chimerism could offer an explanation for the female predisposition to AITD. AIM Our aim was to examine whether skewed XCI is associated with AITD. DESIGNS We first conducted a classical case-control study of twin individuals with and without AITD, and then a case-control study of twin pairs discordant for AITD. PARTICIPANTS Participants included 32 female twins with AITD and a control group of 96 healthy female twin individuals. METHODS XCI analysis was performed by enzymatic predigestion of DNA with a methylation-sensitive enzyme followed by PCR of the polymorphic CAG repeat of the androgen receptor gene. The XCI pattern was classified as skewed when 80% or more of the cells preferentially inactivated the same X chromosome. MAIN OUTCOME MEASURES We assessed the prevalence of skewed XCI. RESULTS The frequency of skewed XCI in female twins with AITD, GD, and HT was 34, 37, and 31%, respectively, which was higher than the prevalence in the corresponding control populations, 11% (P = 0.003), 14% (P = 0.045), and 8% (P = 0.057), respectively. Similar results were found in twin pairs discordant for AITD. Overall, skewed XCI was associated with an increased risk of developing AITD, with an odds ratio of 9.0 (95% confidence interval, 1.64-49.4) (P = 0.022). CONCLUSION These observations suggest a possible role of XCI in the etiology of AITD and may in part explain the female preponderance of AITD.
A clustering-based feature selection via feature separability

With the extensive increase of the amount of data, such as text categorization, genomic microarray data, bioinformatics and digital images, there are more and more challenges in feature selection. Recently, feature selection has been widely studied in supervised learning, but there is significantly less work in unsupervised learning because of the absence of class information and explicit search criteria. In this work, we introduce a new measure to assess the importance of features in terms of feature separability. A clustering-based feature selection algorithm is then introduced to conduct the feature selection. The proposed algorithm with nearly linear time complexity selects final feature subset through a ranking procedure based on the separabilities of features and it is applicable to datasets of mixed nature. Experimental results on UCI datasets show that our method, by retaining relevant features, can obtain similar or even better results of classification and clustering for most datasets, and it outperforms other traditional supervised and unsupervised feature selection methods in terms of dimensionality reduction and classification accuracy.