Miracle-dz/UniFAR-FTUs huggingface dataset:
Electrospun 4th-Generation Solid Dispersions of Poorly Water-Soluble Drug Utilizing Two Different Processes

Different from traditional solid dispersion (SD) for improving the dissolution rates of poorly water-soluble drugs, the upgraded 4th SD was developed to furnish a drug sustained-release profile. In this work, two different kinds of 4th SDs were fabricated using two electrospinning processes. One is a ternary SD (nanofibers F2) that consisted of ethyl cellulose (EC), polyethylene glycol 1000 (PEG), and tamoxifen citrate (TAM) from a modified coaxial process, and the other is a binary SD (nanofibers F1) which is comprised of EC and TAM from a single-fluid blending process. Scanning electronic microscopic observations demonstrated that F2 ( nm) showed a better quality than F1 ( nm) in terms of size and size distribution although both of them had a smooth surface morphology and a cross section. X-ray diffraction patterns verified that both SDs were amorphous nanocomposites owing to the favorable secondary interactions among these components, as suggested from the results of FTIR. In vitro dissolution experiments indicated that F2 could furnish an improved drug sustained-release characteristics compared to F1, exhausting all the contained TAM and having weaker leveling-off late release. The molecular behaviors of drug sustained-release from the binary 4th SD were suggested. The protocols reported here paved an alternative way for developing novel functional nanomaterials for effective delivery of poorly water-soluble drugs.
Stress, Anxiety and Depression among Caregivers of Individual with Psychiatric Disorders

Background: Psychiatric disorders affect the relationship of an entire family. Care-giving burden among family members have known for quite some time. There are various psycho-educational interventions have proved positive effects on burden however very little research has focused on the relationship between family dysfunction, and its role in burden and depression, anxiety, stress among caregivers. Aim: To assess and compare stress, anxiety and depression among male and female caregivers of individual with psychiatric disorders. Methods: cross sectional hospital based study conducted at RINPAS, Kanke, Ranchi (Jharkhand) 100 samples were selected through purposive sampling and informed about purpose of study. Each participant was interviewed at outpatient department of RINPAS. Interview involved socio-demographics and depression, anxiety and stress scale. Result: The result of the study indicated stress, anxiety and depression among the caregivers of persons with psychiatric disorders. Conclusion: the study suggest the psychosocial interventions need of not only the burden specific but also to enhance overall family environment in order to have better adaptive state among family. Key Words: Psychiatric illness, Stress, Anxiety, Depression.
DETERMINANTS OF SUSTAINABLE SUPPLY CHAIN: an analysis of mensuration models of Pressures and Socio-environmental Practices

Sustainability became an important topic concerning the management of the supply chain. Therefore, this study aims to understand the determinant factors of the pressures, and environmental practices on the management of the sustainable supply chain, from the development of two measurement models: 1) pressures and 2) socio-environmental practices accomplished by the companies. The methodology was based on a survey application in processing industries of Minas Gerais state. Data analysis was performed using descriptive statistics, exploratory and confirmatory factor analysis. DOI: 10.12660/joscmv7n2p110-123 URL: http://dx.doi. org/10.12660/joscmv7n2p110-123
Stills, Animations and the Scrollbar as Complementary Multimedia Design Tools

Researchers have been seeking the optimal design guidelines and learning conditions for the use of animated material. The current paper extends this search for a superior multimedia design by proposing a multi-tier structure that incorporates the particular strengths of stills and animations whilst also introducing a third intermediary component, i.e. the scrollbar. Such an “empirically-driven” design seems well suited to learning and rehearsing complex time-critical procedural tasks such as found in the field of sport, dancing, surgery and workplace environments wherein intricate human movement is involved. The three-tiered model is applied to a complex procedural task to illustrate the underlying rationale. An exemplar of best practice in the field of multimedia learning is evaluated in terms of providing complementary input from the viewpoint of an authentic learning scenario. It is recommended that multi-level animations can best accommodate the composite, and sometimes variable, nature of complex information structures.
Internal helminth fauna of Baltic herring, Clupea harengus membras L. (Clupeiformes) from southern Baltic

In the years 1994-1996, a total of 592 specimens of her­ ring Clupea harengus membras L. , caught in southern Baltic, were examined. The investigations revealed four species of trematodes: Hemiurus luhei, H raabei, H levinseni, Brachy­ phallus crenatus, two species of nematodes: Hysterothyla­ cium auctum (syn. H aduncum), and Anisakis simplex and three acanthocephalans: Echinorhynchus gadi, Metechino­ rhynchus salmonis and Pomphorhynchus sp. The finding of H levinseni constitutes the first record of this species in Pol­ ish waters. The infection parameters of hen-ing (prevalence, intensity and abundance) were compared in relation to differ­ ent capture areas and seasons of the year. Possible affects of the feeding ground, fish body length and the spawning group of herring on the infection levels were also examined. No reiation was observed between the place and the sea­ son of catch and the infection level of herring. The fish repre­ senting different feeding grounds (Baltic, Danish Straits) and sequential length classes showed variable parameters of in­ fection.
MAGNETIC NANOPARTICLE EMBEDDED POLYDIMETHYLSILOXANE LAYER FOR REVERSIBLE MICROFLUIDIC BONDING

In polymer microfluidic fabrication, bonding the polymer replicas with another substrate to create enclosed microfluidic channel is essential for success microchip fabrication. Various microfluidic bonding techniques have been reported for higher bonding strength and better stability. However, the microchip sealing from these bonding techniques are usually permanent which can not be open and re-assemble while accessing the sample inside the microfluidic is required. Polydimethylsiloxane (PDMS) is a widely used polymer material in microfluidic cell analysis due to its non-toxic and gas permeability advantages. In cell research, cells cultured inside the microfluidic device are usually need to remove from the chip for post bioanalysis or identification. Thus, in μTAS 2015, we present using magnetic nanoparticles (MNPs) embedded within the PDMS layer as high bond strength reversible bonding method for microchip applications.
Analysis of Peak-to-Peak Current Ripple Amplitude in Seven-Phase PWM Voltage Source Inverters

Multiphase systems are nowadays considered for various industrial applications. Numerous pulse width modulation (PWM) schemes for multiphase voltage source inverters with sinusoidal outputs have been developed, but no detailed analysis of the impact of these modulation schemes on the output peak-to-peak current ripple amplitude has been reported. Determination of current ripple in multiphase PWM voltage source inverters is important for both design and control purposes. This paper gives the complete analysis of the peak-to-peak current ripple distribution over a fundamental period for multiphase inverters, with particular reference to seven-phase VSIs. In particular, peak-to-peak current ripple amplitude is analytically determined as a function of the modulation index, and a simplified expression to get its maximum value is carried out. Although reference is made to the centered symmetrical PWM, being the most simple and effective solution to maximize the DC bus utilization, leading to a nearly-optimal modulation to minimize the RMS of the current ripple, the analysis can be readily extended to either discontinuous or asymmetrical modulations, both carrier-based and space vector PWM. A similar approach can be usefully applied to any phase number. The analytical developments for all different sub-cases are verified by numerical simulations.
KNN classifier based approach for multi-class sentiment analysis of twitter data

‘Sentiment’ literally means ‘Emotions’. Sentiment analysis, synonymous to opinion mining, is a type of data mining that refers to the analy-sis of data obtained from microblogging sites, social media updates, online news reports, user reviews etc., in order to study the sentiments of the people towards an event, organization, product, brand, person etc. In this work, sentiment classification is done into multiple classes. The proposed methodology based on KNN classification algorithm shows an improvement over one of the existing methodologies which is based on SVM classification algorithm. The data used for analysis has been taken from Twitter, this being the most popular microblogging site. The source data has been extracted from Twitter using Python’s Tweepy. N-Gram modeling technique has been used for feature extraction and the supervised machine learning algorithm k-nearest neighbor has been used for sentiment classification. The performance of proposed and existing techniques is compared in terms of accuracy, precision and recall. It is analyzed and concluded that the proposed technique performs better in terms of all the standard evaluation parameters.
STRAIN-SENSING CARBON NANOTUBE CEMENT-BASED COMPOSITES FOR APPLICATIONS IN STRUCTURAL HEALTH MONITORING: PREPARATION AND MODELLING ISSUES

The authors have recently explored the use of electrically conductive cement-based composites doped with carbon nanotubes for dynamic monitoring of strain in concrete structures. While the technology appears to be very promising for cost-effective structural health monitoring, some challenges still limit its applicability to full-scale constructions. The dispersion of the nanoparticles, typically based on sonic treatment and on other special procedures, is not compatible with distributed full-scale deployments and essentially limits the applications of the technology to the fabrication of embeddable sensors. Also, the electromechanical behaviour of the composites is complex and a proper analytical model linking electrical output to accurate strain measurements is yet to be established. This work discusses these open issues in fabrication and modelling of carbon nanotube composite concrete. A fabrication procedure with potential applicability to large casting volumes is presented and experimental results highlighting its effectiveness are discussed. Results cover analysis of nanoparticles dispersion, electrical percolation, strain sensitivity and polarization.
Keep my head on my shoulders!: why third-person is bad for navigation in VR

Head-Mounted Displays are useful to place users in virtual reality (VR). They do this by totally occluding the physical world, including users' bodies. This can make self-awareness problematic. Indeed, researchers have shown that users' feeling of presence and spatial awareness are highly influenced by their virtual representations, and that self-embodied representations (avatars) of their anatomy can make the experience more engaging. On the other hand, recent user studies show a penchant towards a third-person view of one's own body to seemingly improve spatial awareness. However, due to its unnaturality, we argue that a third-person perspective is not as effective or convenient as a first-person view for task execution in VR. In this paper, we investigate, through a user evaluation, how these perspectives affect task performance and embodiment, focusing on navigation tasks, namely walking while avoiding obstacles. For each perspective, we also compare three different levels of realism for users' representation, specifically a stylized abstract avatar, a mesh-based generic human, and a real-time point-cloud rendering of the users' own body. Our results show that only when a third-person perspective is coupled with a realistic representation, a similar sense of embodiment and spatial awareness is felt. In all other cases, a first-person perspective is still better suited for navigation tasks, regardless of representation.
DFT Study of the Interaction of Cu(II), Zn(II), Sn(II) with Carbohydrates in Aqueous Solution

In the present work, authors studied the interaction between carbohydrates as ligands such as L1: fructose, L2: glucose and L3: sucrose with metal(II) halides such as CuCl2, ZnCl2, SnCl2. Also authors compare the stability of the metal-ligand bond strength. DFT (density functional theory) was utilized using the B3LYP functional and the 6-31G(d) basis set. This level of calculation was used for optimization of geometry of ligands and exploring electronic properties such as ionization potential (I), electron affinity (A), chemical potential (μ), hardness (η), band gap (HOMO (highest occupied molecular orbital)-LUMO (lowest unoccupied molecular orbital)). The local reactivity was analyzed by the fukui function indices and the indices local of nucleophilicity in order to predict the sites of attack of carbohydrates. In addition, the strength of interaction has been evaluated by energy lowering and charge transfer using DFT at the B3LYP level employing the basis set Lan2DZ. As a result, the sequence of high stability of metal-ligand bond for ligands is in the following order; sucrose > glucose > fructose. Furthermore, the sequence of high stability for metal halides is in the following order, CuCl2 > SnCl2 > ZnCl2. We advise person who carries a dental amalgam do not exceed the consommation of monosaccharides, because their complexes are not sufficiently stable and hence these ions are not ejected easily outside the human body.
Modeling synaptic facilitation and depression in thalamocortical relay cells

Thalamocortical relay (TC) neurons in the lateral geniculate nucleus receive both retinal and cortical input; however, the two pre-synaptic signals are filtered in significantly different ways. Using a three-compartment model of a TC cell, with distinct equations for the proximal and distal dendrites, we model the synaptic plasticity of feedback signals from the cortex (corticogeniculate facilitation) and feedforward retinal input (retinogeniculate depression). We discuss the use of model-generated cross-correlograms in lending insight into the interplay of the driving and modulating afferents.
Some Consequences of The Economic Crisis in Romania

The international financial crisis has led to a number of effects on the Romanian economy. Altough there had not been reported any direct consequences on the banking system, indirect effects on the economy were felt in full. In this context, the present paper, aims at highlighting numerous macroeconomic effects of the crisis with important economic and social load.
Wideband Dual-Polarized Omnidirectional Antenna with High Isolation for Indoor DAS Applications

A low-profile dual-polarized omnidirectional antenna is presented. The antenna is a combination of a vertically-polarized (VP) antenna and a horizontally-polarized (HP) antenna. The VP antenna is composed of a circular ground plane, a cross-shaped metal patch with four shorted legs and a top-loading circular ring. The printed dipoles of the HP antenna are fed through a three-way power divider etched on an FR4 substrate. To maintain stable radiation and reflection characteristics, the HP feed coaxial cable is soldered on one patch of the VP antenna to reduce the parasitic current on the feed cable. The VP antenna covers the frequency bands for GSM/2G/3G/4G LTE, and the HP antenna works in an overlapping frequency bands for 3G and 4G LTE communication systems with high isolation. The VP antenna achieves a wide bandwidth of 108% from 800 MHz to 2700 MHz, and its gains are larger than 2 dBi in 800∼960 MHz band and greater than 4 dBi in 1710∼2700 MHz band, respectively. The HP antenna works in the frequency band from 1700 MHz to 2700 MHz, and its gains are greater than 3 dBi. The proposed dual-polarized antenna is simulated, fabricated and measured. Measured results are in good agreement with the simulated ones.
A spectral multiplier theorem for non-self-adjoint operators

We prove a spectral multiplier theorem for non-self-adjoint operators. More precisely, we consider non-self-adjoint operators A: D(A) C L 2 → L 2 having numerical range in a sector Σ(w) of angle w, and whose heat kernel satisfies a Gaussian upper bound. We prove that for every bounded holomorphic function f on Σ(w), f(A) acts on L p with L P —norm estimated by the behavior of a finite number of derivatives of f on the boundary of Σ(w).
Relational model of temporal data based on 6th normal form

Original scientific paper This paper brings together two different research areas, i.e. Temporal Data and Relational Modelling. Temporal data is data that represents a state in time while temporal database is a database with built-in support for handling data involving time. Most of temporal systems provide sufficient temporal features, but the relational models are improperly normalized, and modelling approaches are missing or unconvincing. This proposal offers advantages for a temporal database modelling, primarily used in analytics and reporting, where typical queries involve a small subset of attributes and a big amount of records. The paper defines a distinctive logical model, which supports temporal data and consistency, based on vertical decomposition and sixth normal form (6NF). The use of 6NF allows attribute values to change independently of each other, thus preventing redundancy and anomalies. Our proposal is evaluated against other temporal models and super-fast querying is demonstrated, achieved by database join elimination. The paper is intended to help database professionals in practice of temporal modelling.
Influence of age of child on differences in life satisfaction of males and females

Using individual-level data for China, Korea, and Japan for 2006, this research examines how life satisfaction for married males and females in East Asian countries is influenced by the age of their children. Our results show (1) the life satisfaction of females who have a child younger than 12 years old is lower than that of females with no children. (2) The greater the marginal effect of child’s age on the life satisfaction, the more developed a nation’s economic condition.
Is Innovation Being Addressed in Entrepreneurship Undergraduate Programs? An Exploratory Study

Entrepreneurial programs have experienced a phenomenal growth in the past two decades. In this exploratory study the authors survey undergraduate entrepreneurship programs to identify courses that are being offered by these programs with the objective of determining if innovation is being addressed in the programs. The study explores innovation from both startup and corporate perspectives to see if industry needs are being met by academia. Findings suggest that entrepreneurship programs focus on functional knowledge and an opportunity exists to include courses that address innovation, design, intellectual property, and social media. Further research is needed to align market needs with academic offerings in entrepreneurship programs.
Concealed Weapon Detection using Wavelet, Dual Tree Complex Wavelet Transform and Curvelet Transform

In the field of military and law enforcement, detection and visualization of concealed weapons is a common practice. The infrared and visible cameras providing the information i.e., the characteristic visual features of the image and the thermal radiations are able to provide the complementary information like information about concealed objects or weapons. In this manuscript, we have proposed the integration of visible and infrared images of a scene using curvelet, wavelet and Dual Tree Complex Wavelet transform (DTCWT) with their brief introduction and background. The quantitative and visual results obtained from three techniques are compared and they reveal that DTCWT can be efficiently employed as an efficient image fusion tool in the context of concealed weapon detection.
Mechanistic study of angiogenesis induced by shh-transfected BMMSC transplantation after myocardial infarction

Objective: To investigate the changes and mechanism of angiogenesis in myocardium induced by transplantation of the sonic hedgehog (shh) gene transfected in bone marrow mesenchymal stem cells (BMMSC) after myocardial infarction. Methods: A rat model of acute myocardial infarction was made by coronary artery ligation. The rats were randomly divided into five groups of 40 rats each. These were further subdivided into groups of 10 rats. The peripheral regions of the infarcts were injected with either BMMSCSHH (transfection group), equivalent BMMSC (cell only group), BMMSC and pcDNA3.1-Shh DNA mixture (mixture group), pcDNA3.1-shh DNA alone (gene only group), or equal volumes of low-sugar DMEM medium (control group). One, two, four, and eight weeks after transplantation, specimens were harvested from the transplantation site to determine the expression of SHH signaling pathway downstream genes Ptc1, Gli-2, COUP-TF II, angiogenesis promoting factor VEGF, and Ang-1 using RT-PCR. Results: Seven days after transplantation, the expression of SHH signaling pathway downstream genes, Ptc1, Gli-2, and COUP-TF II was significantly more pronounced in the transfection group than in the control group, cell only group, gene only group, or mixture group (Ptc1: P P P P COUP-TF II: P P P P Gli-2: P P P P Vegf and Ang-1 was significantly more pronounced than in the control group, cell only group, or gene only group (Vegf: P P P Ang-1: P P P shh-gene-transfected BMMSCs to the peripheral regions of myocardial infarcts promoted angiogenesis by upregulating downstream gene expression.
Happiness, Media and Sustainability of Communities in Donkeaw, Mearim District, Chiang Mai, Thailand

This study of the ‘happiness’ and ‘sustainability’ in the community of Donkeaw, Amphoe Mae Rim, Chiang Mai Province during the non-election period in Thailand, noted that their happiness levels are in the middle-average range. This was found using a mixed approach of qualitative and quantitative methods (N = 386, α = 0.05). The study explores indicators for six aspects of wellbeing and happiness, including, good local governance, administrative support for the health system that maintains people’s mental and physical health, environment and weather, job security and a regular income aids them in managing a sustainable lifestyle. The impact of economic security and community relationships on social and cultural capital, and the way these aspects impact on the life style of the community, affects the sustainable well-being of people. Moreover, living with transparency and participatory communication led to diverse rewards in many areas. Keywords—Communication, happiness, well-being, Donkeaw community, social and cultural capital.