Miracle-dz/UniFAR-FTUs huggingface dataset:
Kshirapaka Kalpa with special reference to Arjuna Kshirapaka

Ayurveda- the science of life is oldest repository of medical sciences of ancient India. It has two basic objects i.e. maintenance of health and cure of disorders, for this purpose number of Kalpanas (Pharmaceutical forms) are described in accordance with disorders. There are five basic pharmaceutical forms (Panchavidha kashaya kalpana) found in Charaka Samhita. Sushruta has told six forms (Shadvidha kashaya kalpana) including Kshira Kalpana. Thus it is obvious that Kshira Kalpana is original Kalpana referred in Sushruta samhita. In Ashtang Samgraha, similar five Kalpana have been described as found in Charaka Samhita with different names- Niryasa, Kalka, Niryϊha, Shita and Phanta. In conclusion Arjuna Kshirapaka was first time prescribed by Acharya Vrinda in Hridroga, the bark of Arjuna was used to prepare Arjuna Kshirapaka. Kshirapaka is one of the unique preparations of Ayurveda. In fact through this preparation, potency of a drug is transferred into milk. It is worthy to mention here that water soluble as well as fat soluble fraction of a drug dissolve in the kshirapaka kalpana.
WHO classification of tumours of the central nervous system

Representing the first volume in the fourth edition series of the World Health Organization (WHO) Classification of Tumours, this book provides a welcome mix of old and new. Similar to prior versions, it opens with a summary of the recently revised WHO Classification of Tumours of the Central Nervous System (CNS), the remainder of the book being dedicated to a comprehensive yet succinct presentation of the most current knowledge relative to each individual tumor and familial tumor syndrome. The 73 contributing authors have likewise adopted a familiar standardized format with the following subheadings: definition, grading, incidence, age and sex distribution, localization, clinical features, neuroimaging, macroscopy, histopathology, proliferation, genetic susceptibility, genetics, histogenesis, and prognostic and predictive factors. Although a fair number of images have been recycled from previous editions, the majority is new and includes more than 400 full-color photomicrographs and macroscopic images, as well as numerous neuroimages, informative diagrams and charts. A number of tumor entities new to this version of the WHO Classification are explored in detail, including pilomyxoid astrocytoma, atypical choroid plexus papilloma, angiocentric glioma, extraventricular neurocytoma, papillary glioneuronal tumor, rosetteforming glioneuronal tumor of the fourth ventricle, papillary tumor of the pineal region, pituicytoma, and spindle cell oncocytoma of the adenohypophysis. Perhaps the most noticeable improvement comes by way of a voluminous expansion in the genetics sections of the majority of tumor categories. This update parallels the recent explosion of research utilizing high-resolution genome screening and other molecular techniques. The authors have done an outstanding job in distilling the information housed in over 2,500 cited references into a readerfriendly authoritative reference of CNS neoplasia. In summation, the current edition of the WHO Classification of Tumours of the Central Nervous System will serve as an indispensable textbook for all of those involved in the diagnosis and management of patients with tumors of the CNS, and will make a valuable addition to libraries in pathology, radiology, oncology, and neurosurgery departments.
Off-Label Use of Pharmaceuticals: A Detection Controlled Estimation Approach

We identify the rate of off-label use of prescription drugs in the United States during 1993-2008. We apply Detection Controlled Estimation to a comprehensive cross-section of prescriptions and find that rates of off-label use rise from 30.2% to 39.1% during this period. This coincides with a surge in settlements of Department of Justice lawsuits for off-label marketing. Additionally, physicians are more likely to prescribe off-label when there are fewer FDA-approved alternatives and when a patient’s insurance has less restrictive formularies and lower copayments. These substitution patterns are consistent with off-label prescribing by physicians that enhances the welfare of patients.
IRON AND VITAMIN D DEFICIENCY IN A MOTHER AND SON

The impact of maternal malnutrition on neonatal outcomes in developed countries is not always evident: we report a case of an infant whose nutritional compromise at 18 months of age resulted from significant maternal problems during the pregnancy. The case illustrates that antenatal care in London merits attention with respect to micronutrients in order to improve neonatal and toddler health.
Beat-to-beat repolarization duration measurements from ambulatory 24 hour ECG analysis: which is the most reliable method of evaluation?

The quality of repolarization duration measurements is influenced by noise. The variability of 6 standard measures are compared on the basis of 35 Holter ECGs from a practical field study in part highly disturbed. RT/sub max/ corrected by Bazett's formula was found to be the most robust parameter in the given population.
The equine nuchal ligament 2: passive dynamic energy exchange in locomotion

Summary Head and neck movements in horses are characteristic at each gait, implying that the oscillation patterns are an intrinsic part of locomotion. In this study, we examined the head and neck movements of Standardbred horses exercising on a treadmill, and calculated the mechanical work performed by the head and neck segments at the walk, trot and canter. The position of the head and neck relative to the trunk was used to calculate the elastic strain energy stored in the nuchal ligament during the head movements of locomotion. These data allowed us to estimate the proportion of oscillatory work that is contributed by passive components of the equine neck. Elastic strain energy stored in the nuchal ligament contributes 55% of the work of moving the head and neck at the walk, and 33% and 31% respectively at the trot and canter. By substituting passive nuchal ligament work for active muscular work, the horse is able to reduce its metabolic cost of locomotion.
Hepatitis C en pacientes hemodializados: una mirada actual

La hepatitis viral C es un problema de salud publica. En la decada del 90 su prevalencia en las unidades de hemodialisis era significativa, y desde entonces ha disminuido gracias al advenimiento de la eritropoyetina, al control de los donantes y a la mejoria en el cumplimiento de las medidas de bioseguridad. No obstante, se mantiene una elevada incidencia, que supera de 5 a 10 veces la de la poblacion en general. La infeccion generalmente es asintomatica, evoluciona a la cronicidad en el 80 % de los casos y esta relacionada con un aumento de la morbimortalidad en hemodializados y trasplantados renales. Su tratamiento es la monoterapia con Interferon, seguro, eficaz y capaz de inducir respuesta bioquimica y virologica, es costoso y produce reacciones adversas frecuentes. No existe actualmente una vacuna que prevenga su infeccion, por lo que el mejor tratamiento es su prevencion mediante el estricto cumplimiento de las medidas universales de bioseguridad. En el Centro de Hemodialisis, de Cardenas, constituye un problema de salud, por lo cual el proposito de este trabajo fue realizar una actualizacion sobre esta tematica. Se revisaron numerosos trabajos cientificos obtenidos a traves de revistas extranjeras y otros; procedentes de centros de hemodialisis cubanos. Este analisis ha permitido profundizar en factores de riesgo, evaluacion clinica, epidemiologica, de laboratorio y avances en su terapeutica; posibilitando ofrecer guias para su mejor abordaje, y poder contribuir con estos conocimientos a elevar la calidad de la atencion medica a los pacientes.
Complications of intracavernous injections and penile prostheses in spinal cord injured men.

Abstract Erectile dysfunction is a common complication in men who have had spinal cord injury (SCI). This retrospective study focuses on the complications encountered at our institution with both penile prostheses and intracavernous injections in men with SCI. Seventy-two men with SCI were treated with intracavernous injections for erectile dysfunction, and 30 penile prostheses were implanted in 19 men with SCI. Twenty-two of the 72 patients in the intracavernous injection program had adverse effects; none were severe. Prolonged erections lasting four to six hours and ecchymosis were the most common complications. No complication required discontinuation of treatment. There were 23 inflatable prostheses and seven semirigid rods. Mechanical failures occurred in 15 instances, infection occurred in nine, and late erosion occurred in three. Although multiple revisions and replacements were necessary, 14 of the 19 patients had satisfactorily functioning implants at their last outpatient visit. Patients were selected carefully for penile implant placement and yet significant complications and expense were incurred to obtain satisfactory results. Although follow-up has been relatively short, the intracavernous injections of vasoactive medications appear to be a more attractive initial means of treating the erectile dysfunction in men with SCI. The complications are relatively minor and the incidence of prolonged erections has decreased with increased experience. Furthermore, the cost of treatment will be considerably less than that with implant surgery, particularly in view of the high drop-out rate. Although improved implants have decreased the occurrences of mechanical failure, it seems likely that infection and extrusion will continue to be significant problems among men with SCI.
PDI para o Monitoramento de Rodovias com Imagens Aéreas Obtidas por VANT

Aerial images can provide important information for highway management. This paper presents the use of an Unmanned Aerial Vehicle (UAV) in remote sensing of highways, acquiring aerial images, and algorithms that process the images and extract specific parameters. The highway monitoring through aerial images provides a large scan area with reduced time. Through these images it is possible to analyze the traffic information, signalizing, imperfections in the highway and infrastructure management. The presented results demonstrate the viability in applying the image processing algorithms to extract and recognize points of interest on a highway. Keywords— Unmanned Aerial Vehicle, Road Monitoring, Image
Content-based audio search: from fingerprinting to semantic audio retrieval

Aquesta tesi tracta de cercadors d'audio basats en contingut. Especificament, tracta de desenvolupar tecnologies que permetin fer mes estret l'interval semantic o ``semantic gap' que, a avui dia, limita l'us massiu de motors de cerca basats en contingut. Els motors de cerca d'audio fan servir metadades, en la gran majoria generada per editors, per a gestionar col.leccions d'audio. Tot i ser una tasca ardua i procliu a errors, l'anotacio manual es la practica mes habitual. Els metodes basats en contingut audio, es a dir, aquells algorismes que extreuen automaticament etiquetes descriptives de fitxers d'audio, no son generalment suficientment madurs per a permetre una interaccio semantica. En la gran majoria, els metodes basats en contingut treballen amb descriptors de baix nivell, mentre que els descriptors d'alt nivell estan mes enlla de les possibilitats actuals. En la tesi explorem metodes, que considerem pas previs per a atacar linterval semantic.
Successful Cessation of Progression of Hepatocellular Carcinoma with Everolimus Therapy

Management of advanced, unresectable hepatocellular carcinoma patients largely rely upon systemic therapy. Considering poor tolerability of sorafenib and promising role of mTOR inhibitors, everolimus could be a potential therapeutic option. A 65 year old, female patient was diagnosed with advanced hepatocellular carcinoma, ineligible to surgery or transplant. Therapy was started with sorafenib but withdrawn due to dermal toxicity. The patient was switched to everolimus which was continued for 17 months. Everolimus was well tolerated and inhibited the disease progression effectively. At follow up patient demonstrated stable disease with no increase in number or size of the cancerous nodules since diagnosis.
Diagnosis of latent tuberculosis infection: The tuberculin skin test and interferon gamma release assays

The clinical manifestations of tuberculosis (TB) represent a complex interaction between the causative organism, Mycobacterium tuberculosis, and the human host immune response. [1] TB is the most common cause of infectious disease-related mortality worldwide after the human immunodeficiency virus (HIV). The World Health Organization (WHO) estimates that 2 billion people are infected worldwide, and according to the 2010 global TB report, there were an estimated 9.4 million incident cases of TB with 12% of these occurring in HIV-positive patients. [2] The bulk of this disease burden resides in sub-Saharan Africa and the majorities of these infections are asymptomatic and may reactivate later in life. This huge global reservoir is termed latent tuberculosis infection (LTBI) and constitutes an important source of infection and a continuous source of transmission. The goal of testing for LTBI is to identify individuals who are at increased risk for the development of TB and therefore would benefit from treatment. Currently, there is no available gold standard or confirmatory test for the diagnosis of LTBI and available surrogates are not without limitations with respect to technical issues with test performance, cost, specificity, sensitivity, effect of Bacille Calmette-Guérin (BCG) vaccine, and environmental mycobacteria. LATENT TUBERCULOSIS INFECTION
Arazi Toplulaştırması Dağıtım İşleminde Tek Amaçlı Genetik Algoritmanın Kullanılması

Arazi toplulastirmasi projelerinin basarisini dogrudan etkileyen en onemli adim olan blok dagitiminda bircok faktorun dikkate alinmasi gerekmektedir. Blok dagitimi karmasik, uzun zaman alan islemdir ve buyuk olcude dagitimi yapan kisinin bilgi ve tecrubesine baglidir. Bu sorunlar dagitim islemi icin yeni yontemler gelistirilmesi ihtiyacini ortaya cikarmistir. Bu yuzden blok dagitimi icin yoneylem arastirma teknikleri, blok oncelikli model, mekânsal karar destek sistemleri, genetik algoritma ve hibrit dagitim yontemleri gelistirilmeye calisilmistir. Bu calismada; dagitim islemi icin onemli bir sorun olan blok dengelemesi ihtiyacini ortadan kaldiran bir dagitim yontemi onerilmistir. Dagitim, dengeli ulastirma problemi olarak ele alinmis ve tek amacli genetik algoritma kullanilarak gerceklestirilmistir. Bu yontemde blok dengelemesi problemine odaklanilmistir. Bu yuzden dagitim tek bir amac fonksiyonuna gore yapilmistir. Calismada Burdur Golhisar Arazi Toplulastirma Projesi Evciler koyu verileri kullanilmistir. Bu yonteme gore yapilan uygulama sonuclari ile proje sonuclari karsilastirilmistir. Uygulama sonucunda bloklarda eksiklik ya da fazlalik olusmamistir ve blok dengelemesi yapilmamistir. Sonuc olarak genetik algoritma yonteminde toplulastirma orani % 27’den % 41’e yukselmistir.
Otimização de rede de sensores sem fio através de algoritmo de codificação de rede

Resumo— Uma rede de sensores sem fio é um tipo de rede ad hoc que pode ser usada para monitorar uma variedade de caracterı́sticas ambientais em diversos domı́nios com propósitos, por exemplo, militares, ambientais, etc. Um problema tı́pico dessas redes é como coletar e enviar o histórico de informações de todos os nós sensores da rede para a estação base. Neste trabalho são comparadas duas técnicas, usando codificação de rede, para reduzir o número total de transmissões em redes de sensores e o tempo de transmissão, resultando em uma rede mais eficiente. Duas configurações de codificação de redes são implementadas e os resultados comparados com aqueles de uma rede que usa uma simples transmissão por difusão.
The Link between Empirical Aesthetics and Philosophy

This chapter explores the complementary roles that philosophers and psychologists play in the study of art. Psychology provides a natural lens through which to interpret the history of art. Artworks are communicative events. They are cognitive, perceptual, and affective stimuli intentionally designed to express a point or purpose, articulate an idea, or convey some socially embedded meaning. Methodological progress in art is progress in a collective capacity to shape psychological responses in consumers germane to recovering this content. Understanding art in all of its variance is simply a process of tracking how artworks have been used as communicative devices within different social contexts. Philosophers and psychologists study complementary aspects of these communicative exchanges. Despite entrenched philosophical skepticism, the rich, longstanding, albeit often tacit, rapprochement between these two fields should therefore come as no surprise.
Essentials of Nursing Research: Appraising Evidence for Nursing Practice

This eighth edition of "Essentials of Nursing Research, "written by AJN award-winningauthors, along with its accompanying "Study Guide for Essentials of Nursing Research, "student learning ancillaries, and instructor teaching materialspresent a uniquelearning-teaching package that is designed to teach students how to read and critique research reports, and to appreciate the application of research findings to nursing practice.New to this edition: -New text organization with separate sections on quantitative and qualitative research offer greater continuity of ideas to better meet the needs of students and faculty. - New online chapter supplements forevery chapter expand student's knowledge of research topics. - New chapter on mixed methods research, which involves the blending of qualitative and quantitative data in a single inquiry, responds to the surge of interest in this type ofresearch- Increased emphasis on evidence-based practice (EBP) especially in the areas of asking well-worded questions for EBP andsearching for such evidence guides the reader from theory to application. - Enhanced assistance for instructorswithnumerous suggestions on how to make learning about and teaching research methods more rewarding. -New interactive critiquing activity, available on thePoint website, brings theCritical Thinking Exercisesfrom the textbook to an interactive tool. The new format makes it easy for students to respond tothe series of targeted questions about the Research Examples. Responses canbe printed or e-mailed directly to instructors for homework or testing. "
Reações adversas ao benzonidazol no tratamento da Doença de Chagas: revisão sistemática de ensaios clínicos randomizados e controlados

Resumo Introdução No Brasil, a única droga disponível para o tratamento específico do Trypanosoma cruzi, causador da Doença de Chagas (DC) é o Benzonidazol (BZN), cujas reações adversas podem propiciar a interrupção do tratamento. Objetivo O objetivo desse trabalho é quantificar a proporção de ocorrência de efeitos adversos, descrevê-los e identificar os fatores de risco associados à essa ocorrência. Método Revisão sistemática conduzida de acordo com os padrões estabelecidos pelo Preferred Reporting Items is Systematic Reviews and Metanalyses (PRISMA). Incluíram-se somente ensaios clínicos randomizados controlados. Resultados Dos 134 estudos identificados, cinco foram incluídos. O tamanho da amostra variou de 77 a 2854 pessoas, e a faixa etária dos participantes, variou de zero a 75 anos. Todos os estudos incluídos apontaram reações adversas ao uso do BZN. A frequência de reação adversa chegou a 38% e a mais comum foi o rash cutâneo. O abandono do tratamento devido à reação foi citado em três estudos, variando de 6,4% a 13,4%. Conclusão As reações adversas ao uso do BZN variaram de acordo com a idade do paciente e esquema terapêutico de dose e tempo adotado, sendo o conhecimento médico acerca dessas reações imprescindível para seu uso seguro e adesão ao tratamento.
La chute du temps de sommeil au cours de l'adolescence : résultats de l'enquête HBSC 2010 menée auprès des collégiens.

1/ Institut national du sommeil et de la vigilance ; Université Paris Descartes, AP-HP, Centre du sommeil et de la vigilance, Hôtel-Dieu, Paris, France 2/ Institut national de prévention et d’éducation pour la santé (Inpes), Saint-Denis, France 3/ UMR 1027 Inserm, Université Paul Sabatier, Toulouse, France 4/ Service médical du rectorat, Toulouse, France 5/ Centre de recherche Médecine, Sciences, Santé, Santé mentale, Société (Cermes 3) – Équipe Cesames (Université Paris Descartes, Sorbonne Paris Cité/CNRS UMR 8211/Inserm U988/EHESS), Paris, France
CORRELATION OF SERUM LIPID PROFILE WITH GLYCEMIC CONTROL IN TYPE 2 DIABETICS

Objective: To determine serum lipid profile in controlled and uncontrolled Type 2 Diabetics and to know statistically significant differences in serum lipid profile between these two groups. Material and Methods: During study period, 100 Type 2 DM patients, 50 each having good glycemic control (HbA1c 8.2%) were selected on the basis of convenient purposive sampling technique. Brachial venous blood samples were collected for fasting plasma glucose, HbA1c and serum lipid profile from all subjects in the morning after 12 hours fast at presentation in out doors at CMH Kohat laboratory. Their dyslipidemia was compared with reference to glycemic control in type 2 Diabetics. Results: Out of 100 patients, 72% were males and 28% females. The mean age of group 1 was 51.06 and group 2 was 52.86 and total mean of 100 patients was 51.96 with a standard deviation + 7.82 years. Mean total cholesterol was 4.38±1.09 mmol/L in group 1 versus 5.95±1.27 mmol/L in group 2 (P=0.001). Mean Triglycerides were 2.13-±0.74 mmol/L in group 1 versus 3.11±1.00 mmol/L in group 2 (P=0.001). Mean LDL-C was 2.34±0.95 mmol/L in group 1 versus 3.53 ±1.09 mmol/L in group 2 (P=0.001). Mean HDL cholesterol was 1.06-±0.007 mmol/L in group 1 versus 0.99 ±0.008 mmol/L in group 2 (P=0.002). Conclusion: In Type 2 DM patients good glycemic control is associated with statistically significant differences in total cholesterol, triglycerides, LDL-C and HDL-C.
A randomized controlled trial evaluating the quality of life and the sense of coherence in seniors wearing complete conventional dentures or mandibular two-implant overdentures

The superiority and stability of the effect of mandibular two-implant retained overdentures (IODs) over conventional dentures (CDs) in relation to the oral health-related quality of life (OHRQoL) remain to be clarified. Furthermore, the influence of psychological factors, such as the sense of coherence (SOC), on the perception of treatment outcomes is still unknown. The aim of this study was to determine the magnitude of the effect of IODs and CDs on the OHRQoL and assess the stability of the treatment over time taking into account the level of SOC. METHODOLOGY: Edentulous participants (n = 172, mean age 71, SD = 4.5) wearing CDs or IODs were followed up for two years. The OHRQoL was assessed at baseline and both follow-ups using the « Oral Health Impact Profile (OHIP-20) » questionnaire. The SOC was only assessed at both follow-ups using « The Orientation to Life (SOC-13) » questionnaire. Statistical analyses were conducted to evaluate between and within treatment differences (descriptive, bivariate and multivariate statistical analyses). RESULTS: A significant pre-/post-treatment improvement in the OHRQoL for both treatment groups was found (Wilks’s Lambda = 0.473, F (1,151) = 157.31, p < 0.0001). The magnitude of the effect in the IOD group was 1.5 times larger than that in the CD group. These outcomes were stable over the two-year study period and the SOC did not influence any of these results. CONCLUSION: IODs provide better long-term OHRQoL than CDs regardless of SOC level. The results are clinically meaningful and confirm the superiority of IODs over CDs.