Miracle-dz/UniFAR-FTUs huggingface dataset:
Rat-dietary fructose and the intestinal distribution and growth of Moniliformis (Acanthocephala)

SUMMARY The numbers, distribution in the small intestine, sexual development and growth (dry weight) of 5-week-old Moniliformis dubius (Acanthocephala) were investigated experimentally in adult, female CFHB rats fed on theoretically isoenergetic diets containing known amounts of fructose in combination with either maize-oil fatty acids or maize oil and two concentrations of casein. There was no obvious development of M. dubius when there was no fructose in the host's diet. In contrast, estimated consumption by the host of as little as about 2 g of fructose during the 5-week infection period was accompanied by marked sexual dimorphism and weight gain in most of the M. dubius present. The dry weights of M. dubius of both sexes were positively correlated with fructose concentrations ranging from 0 to 2·5 % (w/w) in the diets containing fatty acids. Significant, but not substantial, increases in M. dubius dry weight were observed as the dietary fructose concentration was raised to 12 % (w/w). Similar trends were observed when the fructose was offered to the infected rats with maize oil, but in general, fructose added to the fatty-acid based diets supported most M. dubius growth. Differences in the distribution pattern of the worms in rats fed on the fatty-acid or maize-oil based diets were observed and their possible significance is discussed.
Unleash the parallelism of 3DIC partitioning on GPGPU

Taking full advantage of 3DIC technology requires innovative EDA tools that can optimize a multi-layered complex system. However, the optimization algorithms on the multi-layered 3DIC are usually computationally expensive. Parallel computing has been considered as a solution to manage the exploding computational requirement of future EDA tools. This paper proposes PP3D, a parallel 3DIC partitioning algorithm. PP3D enhances the execution speed by exposing the parallelism of FM algorithm. It also coordinates the parallel execution to retain the optimization quality. A design methodology is proposed to streamline the optimization from PP3D algorithm to the underlying GPGPU many-core architecture. The results on the ISPD98 benchmark demonstrate an average of 15X runtime speedup, while the maximum speedup can reach 37X.
REFLECTIVE TEACHING TOWARD EFL TEACHERS’ PROFESSIONAL AUTONOMY: REVISITING ITS DEVELOPMENT IN INDONESIA

It has been approximately 25 years that reflective teaching in EFL context, particularly in Asia is being encouraged and reviewed. The notable goal emphasizes the teachers’ role as critical lifelong learners in or outside the classroom to bring about continuous mutual development between them and the surroundings. Although myriad research-based studies have paid attention to the developmental praxis of reflective teaching, scant published articles highlight the progress of its empowerment process and quality in Indonesia. Thus, this paper will address some points related to how this realm is being concerned and developed reflecting from the preceding and contemporary discussion and its milestone in Indonesia within Asia scope. Furthermore, the envision of future direction is prompted from current portrait, existing challenges, and expectations concerning the theoretical foundation, means and models, ICT integration, and character education toward 21st-century English teachers’ professional autonomy.
Functional analysis of the early chlorosis factor gene.

Chlorosis is one of the symptoms of bacterial spot disease caused by Xanthomonas campestris pv. vesicatoria, which induces chlorosis before any other symptoms appear on tomato. We report characterization of a 2.1-kb gene called early chlorosis factor (ecf). The gene ecf encodes a hydrophobic protein with similarity to four other proteins in plant pathogens, including HolPsyAE, and uncharacterized gene products from X. campestris pv. campestris and X. axonopodis pv. citri, and, at the tertiary structure level, to colicin Ia from Escherichia coli. We demonstrate that the associated phenotype is hrp dependent, and that the ecf gene product appears to be translocated to host cells. The gene ecf has no impact on electrolyte leakage or on bacterial growth in planta in response to infection. Concentrated culture filtrates do not produce chlorosis. Study of its role in Xanthomonas spp. -tomato interactions will forward our understanding of symptom production by plant pathogens and allows further investigation into the mechanisms of bacterial virulence and production of symptoms.
Fabrication and Investigation of Arrayed Glucose Biosensor Based on Microfluidic Framework

In this paper, an arrayed glucose biosensor is integrated to the poly-dimethylsiloxane microchannel as the microfluidic device for measuring the characteristics of the arrayed glucose biosensor at dynamical conditions. The radio frequency sputtering system and screen printed technology are used to fabricate the arrayed glucose biosensor. Furthermore, the computer numerical control technique is used to fabricate the microchannel mold. The polypyrrole differential reference electrode has good stable characteristics and provides a stable potential for the arrayed pH sensor. At static conditions, the average sensitivity and linearity of the arrayed pH sensor are 57.85 mV/pH and 0.977, respectively. And at dynamical conditions with 20 mL/min flow rate, the average sensitivity and linearity of the arrayed pH sensor are 66.73 mV/pH and 0.993, respectively. The arrayed pH sensor is dropped glucose sensing membranes as an arrayed glucose biosensor. The arrayed glucose biosensor is measured in different glucose concentrations at static conditions, and the average sensitivity and linearity of the arrayed glucose biosensor are 11.84 mV(100 mg/dl)-1 and 0.995, respectively. At dynamical conditions with 25 mL/min flow rate, the average sensitivity and linearity of the arrayed glucose biosensor are 30.41 mV(100 mg/dl)-1 and 0.975, respectively.
Connections between summer air pollution and stagnation

The body of literature on ambient air pollution suggests that atmospheric stagnation events trigger high levels of air pollution. In this paper we use fifteen years (2000–2014) of summertime in situ air quality measurements together with meteorological reanalysis data to examine the temporal correlation of pollutants with the Air Stagnation Index (ASI) on daily timescales. We find that while the direction of the relationship between the ASI and summertime PM2.5 and O3 ranges from near-zero to positive throughout regions comprising the contiguous United States (US), the strength of the relationship is very weak (e.g. in the Northeast the correlation coefficient between the ASI and PM2.5 is 0.09). Moreover, similar to our analysis of the correlation of day-to-day variations of the ASI and pollutants, the percentage of co-occurring extreme pollution and stagnation events is small (e.g. days with a high coverage of stagnation only co-occur with extreme pollution events about one-third of the time in the Northeast). The southern US is an exception to our overall findings as the strength of the relationship between the ASI and pollution is stronger and the percentage of co-occurring events is higher compared with other regions. The results of this study suggest a reevaluation of the ASI as an index to assess meteorological and climatic impacts to air quality.
An Explorative Review of E-Leadership Studies

This study aimed to explore the field of educational leadership and educational technology innovations. In order to understand the extent to which e-leadership was discussed, content analyses on selected conference papers, book chapters, thesis and professional journals spanning across 2000 to 2016 was conducted. An extensive review of the literature found a total of 45 articles mainly on e-leadership, virtual leadership, leading virtual teams, school ICT leadership and e-leaders in both education and non-educational setting. These articles focus on six main themes of e-leadership, which are challenges, leadership styles, trust building, training and development, culture, e-leader skills and guidelines. Findings indicate that empirical studies on e-leadership are scarce and more studies in this area need to be conducted in the digital era. In addition, a proposed model of e-leadership effectiveness and variables that are associated with e-leadership is included in this paper. Subsequently, the missing link for future studies is discussed.
Guidance and Movement Correction Based on Therapeutics Movements for Motor Rehabilitation Support Systems

The use of Virtual and Augmented Reality systems for motor rehabilitation is increasing mainly due to the new interaction tools which enable interaction through body movements. To improve these systems it is important to provide movement guidance and correction according to the therapeutic description of it. The use of natural interaction can help due the understanding of user's intentions, e.g. analyzing their body movements allows the application to provide information and encouragement to them in real time, improving the interaction and the treatment process as a whole. Thus, the aim of this research is to provide guidance and correction to performed movements based on the therapeutic definition of them. This is applied on motor rehabilitation through the use of the Kinect sensor as interaction support tool for rehabilitation systems. The Kinect sensor gives three-dimensional information about the user body, recognizing skeleton and joint positions, however, it does not provide detection of body specific movements. This way, the correct description of therapeutic movement (upper limbs, for instance) was implemented in a prototype. A scoring mechanism was also developed in order to measure the patient performance, as well as to encourage him/her to improve it by displaying a positive feedback whenever he does a correct movement.
Cross-regulation of JAK and Src kinases

Members of the Janus kinase (JAK) family, JAK1, JAK2, JAK3 and Tyk2 are intimately involved in the signalling events initiated by cytokines activating cell surface receptors. They are responsible for phosphorylating these receptors, which create docking sites for downstream molecules such as the signal transducer and activator of transcription family members. In addition, cytokine receptors associate with members of the Src family kinase (SFK). JAKs and SFK work in concert to activate many of the signalling molecules, with both kinase families required for optimal transmission of intracellular signals. JAKs and SFK are also required for the activation and recruitment of negative regulators of cytokine signalling, e.g., protein tyrosine phosphatases (PTPs) and suppressors of cytokine signalling. Aberrant activity of the JAK–Src kinase duet can result in hemopoietic abnormalities including leukaemia. Additionally, the recent identification of a somatic JAK2 mutation as the cause of polycythema vera, further highlights the clinical importance of these molecules.
Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging.

BACKGROUND & AIMS In ulcerative colitis (UC), the epithelial barrier is impaired by erosion/ulcer-type lesions and epithelial apoptosis causing local leaks, and generalized tight junction alterations increasing the basal permeability. We quantified the contribution of these mechanisms to the increased colonic ion permeability. METHODS Sigmoid colon was stripped, and the spatial distribution of current clamped across the viable epithelium was recorded by a microelectrode probe, using the conductance scanning method. Local leaks (circumscribed conductive peaks) were marked, and structural changes were studied in H&E-stained series sections. RESULTS Overall conductivity increased from 8.4 +/- 0.7 mS/cm(2) (mean +/- SEM) in controls to 11.7 +/- 0.6 in specimens with mild inflammation (i.e., with intact epithelium) and 34.4 +/- 6.2 mS/cm(2) in moderate-to-severe inflammation (i.e., with visible epithelial lesions). Only in part this was caused by a generalized increase in basal conductivity (12.2 +/- 1.5 mS/cm(2) in moderate-to-severe UC vs. 8.3 +/- 0.7 in controls). More importantly, the spatial distribution of conductivity, which was even in controls, showed dramatic leaks in UC. Leaks found in mild inflammation without epithelial lesion turned out to be foci of epithelial apoptosis. In moderate-to-severe inflammation, leaks correlated with epithelial erosion/ulcer-type lesions or crypt abscesses. CONCLUSIONS In early UC, but not in controls, seemingly intact epithelium comprises leaks at apoptotic foci. With more intensive inflammation, erosion/ulcer-type lesions are highly conductive, even if covered with fibrin. Local leaks contribute 19% to the overall epithelial conductivity in mild and 65% in moderate-to-severe inflammation.
First identification of polymorphic microsatellite markers in the Burgundy truffle, Tuber aestivum (Tuberaceae)

Premise of the study: Tuber aestivum, the most common truffle in Europe, plays an important role in the commercial truffle market. For the first time, microsatellite primers were developed to investigate polymorphism within this species. Methods and Results: Using direct shotgun pyrosequencing, 15 polymorphic microsatellites were identified out of the 7784 perfect microsatellites present in the 534620 reads obtained. Tested on 75 samples, these microsatellites were highly polymorphic. The number of alleles varied from four to 15, and the expected heterozygosity ranged from 0.266 to 0.620. A multilocus analysis allowed the identification of 63 genotypes over the 75 samples analyzed. Conclusions: Direct shotgun pyrosequencing is a fast and relatively low-cost technique allowing identification of microsatellites in nonmodel species. The microsatellites developed in this study will be useful in population genetic studies to infer the evolutionary history of this species.
Consumer choices among service brands offering ethical attributes

ABSTRACT This research improves understanding of how consumers integrate their evaluations of ethical attributes with other service features in making brand choices. Although consumers appreciate brands they perceive to be ethical, few studies have examined what consumers are willing to give up in order to select a brand that offers specific ethical attributes, and under what conditions they might be willing to do so. To better characterize consumer choice, both compensatory and non-compensatory models are tested; findings suggest that compensatory models, which allow for tradeoffs between attributes, offer better fit. Both healthcare services and banking services are examined, to better understand consumer valuation of ethical attributes under different conditions. The assumptions are made that healthcare services are more variable and require greater interaction with front line providers and service facilities/equipment than do banking services, and findings are discussed accordingly. The results suggest that consumers value ethical attributes significantly more in banking than in healthcare, supporting the idea that services which offer low contact and hence also low variability lead consumers to a greater focus on ethical service attributes. Managerial implications are provided.
Towards multimodal interactions: robot jogging in mixed reality

The recent progress made in the field of Augmented Reality/Mixed Reality (AR/MR) has opened new possibilities and approaches to research areas that can benefit from 3D visualization of digital content in the real world. In fact, human-robot interaction design and the design of user interfaces have very much to gain from MR technologies. Nonetheless, designing the user-robot interaction and processing multimodal feedbacks are very challenging tasks. In this paper we focus in particular on interactions in mixed reality. The main contribution of this paper is the implementation of a control system for an industrial manipulator through the user's interactions with MR content displayed with the Microsoft HoloLens. The system is based on the communication between Unity3D (used to design the user experience) and ROS, therefore extendible to any ROS-compatible robotic hardware.
A novel imaging technique as an adjunct to the in vivo diagnosis of nonmelanoma skin cancer

Background Spectrophotometric intracutaneous analysis (SIAscopy) is a light‐based imaging system capable of producing rapid images of melanin, blood and collagen of the skin. Although the SIAscope has been investigated for melanoma diagnosis, no formal study has been conducted to determine its use in the diagnosis of nonmelanoma skin cancer (NMSC).
Less conservative H∞ filter design for systems with time-varying interval delay

H1 filter design for systems with time-varying interval delay is investigated in this paper. Improved delaydependent H∞ performance condition is presented by using the free-weighting matrix approach and considering the relationship among the time-varying delay, its upper bound and their difference. As a result, a modified cone complementary linearisation (CCL) algorithm with a new stopping condition is employed to derive the filter gain. Finally, a numerical example is given to demonstrate the effectiveness and the benefits of the proposed method.
TLC : creating a culturally responsive school through effective teaching, leadership, and climate.

TLC: CREATING A CULTURALLY RESPONSIVE SCHOOL THROUGH EFFECTIVE TEACHING, LEADERSHIP, AND CLIMATE . vi LIST OF TABLES . xiii LIST OF FIGURES . xiv PREFACE FOR CAPSTONES . xv JOINT INTRODUCTION . 1 Purpose of the Capstone . 2 Significance of the Capstone . 3 STUDY ONE: INTRODUCTION . 5 Purpose . 7 STUDY ONE: LITERATURE REVIEW . 15 Program Implementation . 17 A Conceptual Framework to Social Emotional Learning . 22 Social and Emotional Learning: History and Effectiveness . 26
Internal and External Sources and the Adoption of Innovations in Organizations

Research on knowledge sources and innovation has focused mainly on external knowledge sources and the generation of technological innovations. This study contributes by examining the dual role of internal and external sources of knowledge and information on the adoption of managerial innovations, a type of non&#8208;technological innovation deemed essential for organizational effectiveness but not examined sufficiently. It also contributes to the innovation adoption literature by analysing adoption as a process, rather than a dichotomous choice. We investigate how the involvement of stakeholders for the selection of a new programme, and organizational actions for the implementation of that programme, affect its adoption. Regression analyses of privatization of 64 services in 1,512 public organizations provide empirical evidence in support of the influence of internal and external involvement, and internal, but not external, implementation actions. We also find that while the relative influence of internal and external stakeholders&#8217; involvement on innovation adoption does not differ, internal implementation actions have a stronger effect than external implementation actions. We discuss the implications of our findings for the adoption of innovations in organizations and offer research ideas for understanding non&#8208;technological innovations and their effects on organizational conduct and outcomes.
Cloned pigs generated from cultured skin fibroblasts derived from a H‐transferase transgenic boar

Cloned pigs were produced from cultured skin fibroblasts derived from a H‐transferase transgenic boar. One 90 day fetus and two healthy piglets resulted from nuclear transfer by fusion of cultured fibroblasts with enucleated oocytes. The cells used in these studies were subjected to an extensive culture time, freezing and thawing, and clonal expansion from single cells prior to nuclear transfer. PCR and FACS analysis determined that the cloned offspring contained and expressed the H‐transferase transgene. Microsatellite analysis confirmed that the clones were genetically identical to the boar. The cell culture and nuclear transfer procedures described here will be useful for applications requiring multiple genetic manipulations in the same animal. Mol. Reprod. Dev. 60: 189–195, 2001. © 2001 Wiley‐Liss, Inc.
Telomere loss in relation to age and early environment in long-lived birds

Shortening of telomeres, specific nucleotide repeats that cap eukaryotic chromosomes, is thought to play an important role in cellular and organismal senescence. We examined telomere dynamics in two long–lived seabirds, the European shag and the wandering albatross. Telomere length in blood cells declines between the chick stage and adulthood in both species. However, among adults, telomere length is not related to age. This is consistent with reports of most telomere loss occurring early in life in other vertebrates. Thus, caution must be used in estimating annual rates of telomere loss, as these are probably not constant with age. We also measured changes within individuals in the wild, using repeat samples taken from individual shags as chicks and adults. We found high inter–individual variation in the magnitude of telomere loss, much of which was explained by circumstances during growth. Individuals laying down high tissue mass for their size showed greater telomere shortening. Independently of this, individuals born late in the season showed more telomere loss. Early conditions, possibly through their effects on oxidative stress, appear to play an important role in telomere attrition and thus potentially in the longevity of individuals.
Probiotics in Irritable Bowel Syndrome: An Immunomodulatory Strategy?

The clear delineation of a post-infective variety of IBS, as well as the description, in a number of studies, of evidence of low-grade inflammation and immune activation in IBS, suggest a role for a dysfunctional relationship between the indigenous flora and the host in IBS and, accordingly, provide a clear rationale for the use of probiotics in this disorder. Other modes of action, including bacterial displacement and alterations in luminal contents, are also plausible. While clinical evidence of efficacy is now beginning to emerge, a review of available trials emphasizes the importance of a clear definition of strain selection, dose and viability. The possible roles of co-therapy or sequential therapy with antibiotics, probiotics, prokinetics, or other agents also deserves further study. The role of the enteric flora is evidently an area of great potential in IBS; we are on the threshold of a new era of research and therapy for this common disorder.
Update of tacrolimus in pancreas transplantation

Pancreas transplantation for the better treatment of diabetes mellitus is becoming an important part of the service offered to diabetic patients requiring renal transplantation. Improvements in surgical technique make this a useful option. A major problem, limiting more extensive use of pancreas transplantation to other diabetic patients, remains the inadequacies of present immunosuppressive regimens. A relatively new agent, FK506 or tacrolimus, is being used increasingly because of perceived benefits over older therapeutic agents. There are concerns about the diabetogenic effect of tacrolimus. These may be dose‐related, and low‐dose tacrolimus regimens, by allowing reduction in dosage of other diabetogenic immunosuppressive agents, have produced encouraging results in pancreas transplantation in many centres. Further improvements in immunosuppressive regimens may widen the clinical implications for pancreas transplantation but identifying the patient group who will most benefit remains a priority. © 1997 John Wiley & Sons, Ltd.