Miracle-dz/UniFAR-FTUs huggingface dataset:
Business Incubation Models in Institutionally Void Environments: Evidence from Egypt

This paper builds a conceptual framework of business incubation models in institutionally void environments, a relevant yet understudied topic in the extant literature. On the basis of case studies drawn from a sample of business incubators in Egypt and grounding on the resource dependence theory and the literature on institutional voids, we posit that there is a necessity for two different incubation models in institutional laggard environments, typically found in, yet not limited to, developing countries. In particular, we show evidence that the two models supply and facilitate different needs of entrepreneurs, in different stages of entrepreneurial life cycle. We further argue that the incubation model choice is contingent on the incubator sponsors, i.e. affiliation of the incubator, mainly through available resources and imposed objectives. Finally, we offer implications for policy makers who can use the framework to design the regulations in a way that will stimulate appropriate incubator creation and hence sustain local entrepreneurship, as well as for incubator managers who can follow the findings to position their incubation model in line with their resources, capabilities and objectives.
Family caregivers and indicators of cancer-related distress

Increases in the cost of medical care coupled with shorter hospital stays and an aging population are but a few of the reasons why home care for patients has become so important. This study examines variables that contribute to distress among lay-caregivers who provide home care to cancer survivors. Participants consisted of 135 survivor-caregiver dyads in which the caregiver was a member of the survivor's family or a close friend. Measures of caregiver distress were selected from the Ferrell et al. (1995) quality of life tool; predictor variables included cancer survivor and caregiver demographics, physical and emotional health status and behavioural characteristics. Hierarchical regression analysis indicated that, jointly, the three sets of indicators accounted for 35% of caregiver distress. Standardized regression coefficients indicated that relational deprivation (feelings of loss of togetherness, planned activities and contact with other individuals) was the most important predictor of caregiver distress (p<0.01). Female sex, less practice of healthy behaviours, greater number of patient care needs and pessimistic expectations (all ps<0.05) also were significant predictors in the final trimmed model. Results suggest that cancer support services that address the needs of the care receiver with the protection of the family caregiver in mind should be considered.
Reliability study of 3D-WLP through silicon via with innovative polymer filling integration

This paper deals with an innovative via-last TSV polymer filling process dedicated to straight (non-slopped), high aspect ratio (2:1 to 5:1) TSV, partially filled with copper. New polymers were investigated for this purpose. Firstly, the need for a polymer filling process is pointed out. Potential reliability issues added by this new process are developed through finite element modelling. Secondly, the filling process and the optimization phase in order to obtain a void free polymer inside the TSV are presented. A complete integration of polymer filling on electrical test vehicle is then performed. Finally, the impact of polymer filling on the TSV electrical performances is presented. Electrical tests are performed on chains of 10 and 100 TSV in order to check critical parameters such as electrical resistance. A reliability study of TSV polymer filling through JEDEC standard harsh temperature cycling is presented. First results of a comparison of the stack behaviour between a standard RDL polymer insulation and our innovative TSV polymer filling process is performed by means of morphological and electrical characterizations of the TSV before and after cycling.
The Tablet Formulation of Lopinavir/Ritonavir Provides Similar Bioavailability to the Soft-Gelatin Capsule Formulation With Less Pharmacokinetic Variability and Diminished Food Effect

Lopinavir, an HIV protease inhibitor, is coformulated with ritonavir to enhance the bioavailability and pharmacokinetics of lopinavir. The original solid oral formulation of lopinavir/ritonavir, a soft-gelatin capsule (SGC), requires refrigerated storage, is taken as 6 capsules daily at the recommended adult dose, and is administered with food to maximize the bioavailability of lopinavir. Melt extrusion technology was used to produce a tablet formulation reducing the number of dosage units administered per day and simplifying storage requirements. Three studies assessed the bioavailability of tablet doses of lopinavir/ritonavir at 800/200 mg or 400/100 mg under different meal conditions compared with equal doses of the SGC after a moderate-fat meal. The tablet was bioequivalent to the SGC after a moderate-fat meal with respect to lopinavir and ritonavir areas under the concentration-time curve. Compared with the SGC formulation, the tablet formulation resulted in more consistent lopinavir and ritonavir exposures within and across studies and across meal conditions. The diminished food effect and decreased variability of the tablet are likely to result in more consistent lopinavir and ritonavir exposures, minimizing the likelihood of extreme high or low values compared with the SGC.
Effects of metal spacing and poly-silicon layers on pulsed-laser single event transient testing

This paper investigates the influence of metal spacing and poly-crystalline silicon gate and silicide technology on single event transients (SETs) occurring in pulsed laser irradiated test patterns based on 0.18 μm partially depleted silicon-on-insulator complementary-metal-oxide-semiconductor technology. Laser-induced transients were measured and analyzed in detail, including SET rise time, fall time, pulse width, pulse maximum, and collected charge. The quantitative dependence of the SET characteristics on metal spacing and silicide processing is reported. This information is useful for optimal design of test structures to evaluate soft errors in integrated circuits.
Otospongiosis and Sodium Fluoride

The effect of sodium fluoride treatment in patients with otospongiosis has been evaluated blindly in a morphological and microchemical element analysis of otospongiotic specimens together with a prospective clinical double-blind, placebo-controlled study. The results show that using the calcium phosphorus ratio as an indication for bone maturity, the sodium fluoride treatment can stabilize otospongiotic lesions in retaining calcium relative to phosphorus. The clinical double-blind, placebo-controlled study of 95 patients showed a statistically significant worse deterioration of the hearing loss in the placebo group than in the active treated (40 mg sodium fluoride daily) group, supporting the view that sodium fluoride can change otospongiotic, active lesions to more dense, inactive otosclerotic lesions. We have postulated in the past that the actual mechanism of the cochlear loss is toxic enzymes produced by histiocytes at the periphery of the microfoci, and it may be that sodium fluoride has some effect on these enzymes.
Gröbner Bases Techniques for an $S$-Packing $k$-Coloring of a Graph

In this paper, polynomial ideal theory is used to deal with the problem of the $S$-packing coloring of a finite undirected and unweighted graph by introducing a family of polynomials encoding the problem. A method to find the $S$-packing colorings of the graph is presented and illustrated by examples.
NJUST @ CLSciSumm-17

This paper introduces NJUST system which is applied in the CLSciSumm 2017 Shared Task at the BIRNDL 2017 Workshop. The training corpus contains 10 articles of training set, 10 articles of development set and 10 articles of test set from CL-SciSumm 2016. Articles were created by randomly sampling documents from the ACL Anthology corpus and selecting their citing papers. In Task 1A, we utilize different measurements to compute sentence similarities. Four classifiers are trained using different features and final results are obtained by voting system. In Task 1B, rule-based methods are mainly used according to high frequency words. As to Task 2, we generate a summary within 250 word based on the identified sentences in the reference paper from its cited text spans using maximal marginal relevance.
Studies in Diabetic Pregnancy: I. Serum Lipids

Abstract. The serum lipid values at different stages of pregnancy in twenty‐six pregnant diabetic women attending a special antenatal clinic at the Department of Obstetrics and Gynecology, were compared with the corresponding values in four control series composed of non‐diabetic pregnant women. Control series were studied at weeks 10, 22, 34 and after delivery, respectively. Serum triglycerides were higher in the diabetic women at week 10 (p>0.01), week 34 (p>0.05) and after delivery (p>0.05). Furthermore, in the diabetic women, infant birth weights were correlated (r=0.52, p=0.05) with maternal serum triglyceride values at week 31. Women with the highest serum triglyceride values (<250 mg/100 ml) were delivered of infants with a higher birth weight (p>0.05) than those women with lower serum triglyceride values (>250 mg/100 ml). Intra‐uterine deaths (n=4) were not related to maternal serum triglyceride values, but mean blood glucose values (during the whole pregnancy) were higher (p>0.001) in mothers with intra‐uterine deaths. Elevated plasma free fatty acids (FFA) in the diabetic mother would be a possible cause for elevated serum triglycerides through increased liver triglyceride synthesis, while in the fetus an excess of plasma FFA (passing through the placental barrier) together with normal or elevated plasma insulin would be a likely explanation for increased triglyceride synthesis in adipose tissue and thereby of increased fat depots and body weight.
Data-Driven Finite-Horizon Approximate Optimal Control for Discrete-Time Nonlinear Systems Using Iterative HDP Approach

This paper presents a data-based finite-horizon optimal control approach for discrete-time nonlinear affine systems. The iterative adaptive dynamic programming (ADP) is used to approximately solve Hamilton-Jacobi–Bellman equation by minimizing the cost function in finite time. The idea is implemented with the heuristic dynamic programming (HDP) involved the model network, which makes the iterative control at the first step can be obtained without the system function, meanwhile the action network is used to obtain the approximate optimal control law and the critic network is utilized for approximating the optimal cost function. The convergence of the iterative ADP algorithm and the stability of the weight estimation errors based on the HDP structure are intensively analyzed. Finally, two simulation examples are provided to demonstrate the theoretical results and show the performance of the proposed method.
Co‐administration of CD40 agonistic antibody and antigen fails to overcome the induction of oral tolerance

T‐cell stimulation in the absence of a second, costimulatory signal can lead to anergy or deletion. There is growing evidence that peripheral tolerance to an exogenous antigen might be caused by the lack of costimulatory molecules on antigen‐presenting cells (APCs). In the present study, we examined whether tolerance against orally administered antigen could be reversed by maturation of APCs via CD40 signalling. Monoclonal antibody (mAb) to CD40 efficiently induced costimulatory molecules on APCs. Treatment with anti‐CD40 mAb potentiated the division of ovalbumin‐specific T cells in response to oral ovalbumin in secondary lymphoid organs. However, such treatment did not prolong the presentation of oral ovalbumin on APCs. Surprisingly, treatment of anti‐CD40 mAb at the time of oral administration of ovalbumin did not reverse the induction of tolerance to ovalbumin in either the high‐ or low‐dose regimens. Furthermore, the induction of oral tolerance in our model is not the result of negative signalling by cytotoxic T‐lymphocyte antigen‐4. These results indicate that tolerance for oral antigen could be established regardless of APC maturation by a CD40‐specific mAb, suggesting that there could be a unique mechanism to regulate immunity versus tolerance to encountered antigen in the gut‐associated lymphoid tissue.
Do students value feedback? Student perceptions of tutors’ written responses

The topic of feedback to students is an under‐researched area, and there has been little empirical research published which focuses on student perceptions. This study explores student perceptions of written feedback and examines whether feedback received demonstrated a student‐centred approach to learning. A multi‐method approach of qualitative and quantitative data collection and analysis was used to survey 44 students in the faculties of Business and Art & Design. Student responses show feedback is valued, but believed tutor comments could be more helpful. Survey results indicate that students may need advice on understanding and using feedback before they can engage with it. Content analysis of feedback samples and student responses uncovered four main themes of feedback considered unhelpful to improve learning: comments which were too general or vague, lacked guidance, focused on the negative, or were unrelated to assessment criteria. It is suggested that by focusing on messages conveyed by their writing, providing feedback set in the context of assessment criteria and learning outcomes, and by ensuring that it is timely, tutors could greatly improve the value of feedback.
Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal investigation of thromboembolism etiology (LITE)

We sought to examine prospectively the association of serum homocysteine and the methylene tetrahydrofolate reductase (MTHFR) C677T gene polymorphism with risk of venous thromboembolism (VTE). We studied these relationships in a nested case–control study of 303 VTE cases and 635 matched controls from a population‐based cohort of 21,680 adults from six U.S. communities. The highest quintile of serum homocysteine carried a non‐statistically significant adjusted odds ratio of 1.55 (95% CI, 0.93–2.58) compared to the lowest quintile in the overall cohort but a significant association among adults aged 45–64 years (OR = 2.05, 95% CI, 1.10–3.83) and an inverse association in those ≥65 years of age. Carriers of the MTHFR C677T polymorphism were not at higher risk for VTE than those with normal genotype (OR = 0.74, 95% CI = 0.56–0.98). Our prospective data showed, at most, a weak relationship between homocysteine and VTE risk, with associations larger among younger participants. MTHFR C677T was not a risk factor for VTE. Am. J. Hematol. 72:192–200, 2003. © 2003 Wiley‐Liss, Inc.
The Consequences of Hyperandrogenism in Young Women

These words, put into the mouth of Banquo when he and Macbeth came across the three witches, are an evocation of the dismay caused by encountering a grossly hirsute woman. The reaction of the woman herself is often much stronger, with horror at her disfigurement and fear that the external signs may be but the superficial manifestation of an uncontemplatable transition towards masculinity. Thus disorders of androgen secretion and action in the female, said to occur in 3% of a Caucasian population 1, demand tact and sensitivity in their management, which, ifit is to be successful, requires a sound knowledge of pathogenesis. It is the purpose of this paper to set such disorders in an historical and cultural context and to discuss the biochemical mechanisms that bring them about.
Accounting Choice in Troubled Companies: An Examination of Earnings Management by NASDAQ Firms in Jeopardy of Delisting

The purpose of this research is to examine whether managers of troubled firms engage in income-increasing earnings management for capital market purposes to maintain a listing on the NASDAQ National Market. Troubled firms are defined as those firms whose share price has fallen below the specified dollar-per-share minimum mandated by the market. The two hypotheses attempt to answer two separate, but interrelated questions: First, do managers of troubled firms engage in earnings management more in periods of distress than in periods of non-distress? And second, do managers of troubled firms engage in earnings management more than similar firms not in jeopardy of delisting? Both a time-series and cross-sectional approach is used to answer these questions. The initial grouping consisted of all NASDAQ National Market firms with a share price of $1 or below at some point during the period from March 1997 through September 2002. The final sample consisted of 215 firms for the time-series analysis and 495 firms for the cross-sectional analysis. Two accrual expectation models were used, including the Jones (1991) and the modified Jones Model (Dechow, Sloan, and Sweeney, 1995). The results were unable to confirm that managers engage in this behavior, and similar to the results of DeAngelo, DeAngelo, and Skinner (1994), the findings suggest that managers’ accounting choices primarily reflect their firms’ financial difficulties, rather than attempts to inflate income through discretionary accruals. After controlling for reverse stock splits, dividend reductions, going-concern issues/bankruptcy, and changes in management, the models found significantly negative abnormal accruals. The dissertation concludes with a discussion of possible interpretations for the findings.
De relatie tussen waardecreatie en koersontwikkeling voor Nederlandse ondernemingen

Reeds enkele jaren is het creëren van aandeelhouderswaarde expliciet als doelstelling verwoord door vele Nederlandse ondernemingen, door met name beursgenoteerde ondernemingen. Om deze ‘nieuwe’ doelstelling te operationaliseren zijn Value Based Management (VBM) trajecten opgestart. De meest toegepaste methode, binnen de kaders van VBM, om waardecreatie te meten is de EVA-methode (Economic Value Added), geïntroduceerd door Bennett Stewart (1991). Voor intern gebruik, binnen de Planning en Control-cyclus, heeft EVA haar nut reeds bewezen (Rijken en Claes, 2001a). Het zet naast winst ook de vermogenskosten op de agenda en zorgt daarmee voor de juiste prikkels in een onderneming om zoveel mogelijk winst te maken met zo weinig mogelijk vermogenskosten.
Business models for electronic markets

sive development in electronic commerce. The reasons for that are, of course, the Internet and the World Wide Web, which are making electronic commerce much more accessible. They offer easily usable and low cost forms of electronic commerce. Electronic commerce on the basis of the Internet is set to become a very important way of doing business. Forrester (1997) forecasts that businessto-business (B-to-B) electronic commerce will grow to $327 billion in the year 2002 — that is the value of goods and services traded via the Internet. This excludes the value of the hardware, software and services that are needed to perform electronic commerce, whose value is estimated at several hundred billions of dollars likewise. Between 1996 and 1997 electronic commerce has been growing at over 1000 percent per year. While such high growth rates will not be sustained, it is clear that electronic commerce will become pervasive: Datamonitor (1997) expects in 5 years time 630,000 US companies and 245,000 European companies to be involved in fullfledged integrated B-to-B electronic commerce. The Report on Electronic Commerce (1998) expects that the business-to-business penetration rate will grow from 10% in 1997 to 90% in 2001.
A phase III, randomized, double-blind, multicenter study comparing monotherapy with ipilimumab or gp100 peptide vaccine and the combination in patients with previously treated, unresectable stage III or IV melanoma.

4 Background: Ipilimumab, a fully human monoclonal antibody against cytotoxic T-lymphocyte antigen-4, demonstrated activity in advanced melanoma. Gp100 vaccine showed immunological and clinical responses, and enhanced clinical activity when combined with other immunotherapy. This phase III study compared efficacy and safety of ipilimumab or gp100 monotherapy and combination. METHODS Eligible patients (HLA-A*0201+ previously treated adults with unresectable stage III/IV melanoma) were randomized 1:3:1 to ipilimumab (3 mg/kg q3w x 4 doses) + placebo (n=137), ipilimumab + gp100 (peptides 209-217[210M] and 280-288 [288V]; 1mg q3w x 4 doses; n=403), or gp100 + placebo (n=136). There was no maintenance phase. Primary endpoint was comparison of overall survival (OS) between patients who received combination versus gp100 alone; secondary endpoints were all other OS comparisons, best overall response rate (BORR), disease control rate (DCR) to W24, progression-free survival (PFS), and safety. RESULTS The study demonstrated statistically significant results for all efficacy endpoints (below). Ipilimumab alone or combined with gp100 resulted in a significant improvement in OS with risk reduction of 32-34% compared to gp100. Significant differences in DCR, BORR, and PFS were observed. Adverse events with ipilimumab were consistent with prior studies: generally mild, immune-related, and medically manageable. CONCLUSIONS Ipilimumab is the first agent to improve median and long-term OS in a phase III study of previously treated patients with advanced melanoma. Addition of gp100 vaccine to ipilimumab did not improve outcome. [Table: see text] [Table: see text].
FACTORS INFLUENCE DATA MANAGEMENT MODELS SELECTION

Data Management Models selection (Centralized Data Model or Federated Data Model) for managing organization data is influenced by many factors. This paper explains 21 factors that are useful to select an architectural model. Information technology leaders must understand the impact of factors such as cost, quality, and availability on the model selections. The study indicates that all factors except for Training, Reliability, Scalability, and Maintainability were found to be significantly contributed to the selection of the Data Management architectural model.
Health Among Leaders: Positive and Negative Affect, Engagement and Burnout, Forgiveness and Revenge

The health of an organization's leader has profound implications not only for the leader, but also for the organization itself and for its members. This study focused on three indicators (positive affect, engagement, forgiveness behaviours) of eustress, the positive stress response, and three indicators (negative affect, burnout, revenge behaviour) of distress, the negative stress response, in relation to the health of pastors, whose jobs closely parallel those of leaders in all types of organizations. Results indicated that both positive affect and revenge behaviour were significantly related to health. A post-hoc analysis indicated that work-family conflict was negatively related to revenge behaviour, while family-work conflict was positively related to revenge behaviour, and that engagement was negatively related to revenge behaviour. These results are discussed in terms of their implications for future studies of leader health, and their practical applications for promoting leader health while preventing distress.
CSR Policy of Polish and Turkish Enterprises – Comparison (Polityka CSR Polskich I Tureckich Przedsiębiorstw -Porównanie)

Corporate Social Responsibility (Eng. CSR) has been developing both in the world and in Turkey in recent years and it directly affects organizations' marketing related to branding activities. Companies conduct a lot of different activities within this issue which are very effective in fields such as public relations and brand communication. This paper includes Corporate Social Responsibility case studies conducted in selected Turkish and Polish enterprises in terms of corporate social responsibility policies and brand promotion activities.