Miracle-dz/UniFAR-FTUs huggingface dataset:
Photobacterium proteolyticum sp. nov., a protease-producing bacterium isolated from ocean sediments of Laizhou Bay.

A protease-producing bacterial strain, 13-12T, was isolated from the ocean sediment of Laizhou Bay, PR China and systematically studied. The bacterium was Gram-stain negative, non spore-forming rods, which were motile with two flagella. It was positive for oxidase, the hydrolysis of starch, agar and gelatin, and for nitrate reduction. It was negative for catalase, esterase and the degradation of CM-cellulose. Optimum growth was observed at 28 °C, pH 6.5-7.0 and in the presence of 2-3 % (w/v) NaCl. Phylogenetic analysis of the 16S rRNA gene, and whole genome data, affiliated it to the genus Photobacterium. It was most closely related to Photobacterium jeanii R-40508T (96.7 % 16S rRNA gene similarity). Strain 13-12T was found to have less than 86.1 % similarities with the type strains of its most closely related species in multi-locus sequence analysis, less than 75.2 % using genome average nucleotide identities (ANI), and less than 18.5 % in DNA-DNA relatedness studies. Q8 was the predominant respiratory menaquinone. Phosphatidylethanolamine, phosphoaminolipid and phospholipid were the major polar phospholipids and summed feature 3 (48.2 %), C16 : 0 (18.4 %) and C18 : 1ω5c (14.1 %) the major fatty acids. The combined phenotypic, phylogenetic, genomic and chemotaxonomic data support this strain representing a novel species of the genus Photobacterium, for which the name Photobacterium proteolyticum sp. nov. is proposed, with 13-12T (=KCTC 42764T=CGMCC 1.14970) as the type strain. The genome size of 13-12T is 6.2 Mbp, comprising 5806 predicted genes and the DNA G+C content is 47.9 mol%.
IPA for delay threshold violation using stochastic fluid models

In this paper we investigate the problem of delivering quality of service (QoS) guarantees in the context of communication networks, studied through stochastic fluid models. The paper follows the approach developed in (C. G. Cassandras, et al., 2002), (C. Panayiottou, et al., 2004). Its main contribution is that it develops infinitesimal perturbation analysis (IPA) estimators of a cost function that also includes delay violation constraints, rather than the average delay that is typically investigated in [1], [2] and other similar work.
Meningococcal disease: The advances and challenges of meningococcal disease prevention

Vaccination as a means to prevent meningococcal disease caused by Neisseria meningitidis is critical given the abrupt onset and rapid progression of this disease. Five serogroups-A, B, C, W-135, and Y-are responsible for the majority of cases. In developed countries, infants have the greatest risk of disease, with a smaller secondary peak observed in late adolescence. Vaccines utilizing the polysaccharide capsule are poorly immunogenic in young children but can reduce the incidence of meningococcal carriage in high risk groups. In contrast, protein conjugate vaccines to polysaccharide capsules A, C, W-135, and Y have broadened the population protection from disease but their effect on meningococcal carriage and transmission is yet unknown except for monovalent meningococcal C conjugate that has been shown to reduce carriage. Challenges remain in providing direct protection to infants and protection against meningococcal B disease. To date, outer membrane vesicle vaccines have been used to control meningococcal B disease in epidemic settings and vaccine candidates against subcapsular antigens are in development, but a vaccine that confers long-lasting protection is unavailable.
Issues and considerations regarding the use of assessment instruments in the evaluation of competency to stand trial.

Since the early 1960s, a number of instruments, reflecting a broad range of assessment methods, have been developed to assist in the evaluation of competency to stand trial. These instruments have taken various forms including checklists, self-report questionnaires, sentence-completion tasks, and interview-based instruments with and without criterion-based scoring. This article reviews these assessment instruments with a specific focus on their contribution to the competency evaluation process. Furthermore, relevant issues and considerations regarding the use of these instruments are outlined, including a comparison of screening versus assessment applications of these instruments, balancing standardized approaches with individualized assessments, the integration of instrumentally derived data with other components of a competency evaluation, and the communication of results to the fact finder. Each of these issues is discussed in relation to specific competency assessment instruments. Overall, we argue that each of the competency assessment instruments developed to date can make a contribution to the competency evaluation process and this article serves to delineate those areas in which these contributions are made.
Oestrogen upregulates the expression levels and functional activities of duodenal mucosal CFTR and SLC26A6

What is the central question of this study? Duodenal ulcer is a common disease. A sex‐based difference in the incidence of duodenal ulcer has long been observed clinically, but the cause is unclear. What is the main finding and its importance? Duodenal mucosal bicarbonate secretion is the most important protective factor in duodenal mucosa against acid‐induced damage. The cystic fibrosis transmembrane conductance regulator (CFTR) and the solute‐linked carrier 26 gene family A6 (SLC26A6) are two key bicarbonate transport proteins that mediate duodenal mucosal bicarbonate secretion. We demonstrate that endogenous oestrogen upregulates the expression levels and functional activities of duodenal mucosal CFTR and SLC26A6, which contributes to the sex difference in the prevalence of duodenal ulcer.
Functional Interaction of the Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 Polymorphism and HLA-B27 in Vivo*

The association of ERAP1 with ankylosing spondylitis (AS)1 among HLA-B27-positive individuals suggests that ERAP1 polymorphism may affect pathogenesis by altering peptide-dependent features of the HLA-B27 molecule. Comparisons of HLA-B*27:04-bound peptidomes from cells expressing different natural variants of ERAP1 revealed significant differences in the size, length, and amount of many ligands, as well as in HLA-B27 stability. Peptide analyses suggested that the mechanism of ERAP1/HLA-B27 interaction is a variant-dependent alteration in the balance between epitope generation and destruction determined by the susceptibility of N-terminal flanking and P1 residues to trimming. ERAP1 polymorphism associated with AS susceptibility ensured efficient peptide trimming and high HLA-B27 stability. Protective polymorphism resulted in diminished ERAP1 activity, less efficient trimming, suboptimal HLA-B27 peptidomes, and decreased molecular stability. This study demonstrates that natural ERAP1 polymorphism affects HLA-B27 antigen presentation and stability in vivo and proposes a mechanism for the interaction between these molecules in AS.
The incidence and risk factors for deep vein thrombosis after kidney transplantation in Korea: single‐center experience

The incidence of deep vein thrombosis (DVT) after kidney transplantation (KT) and the risk factors are still unknown in Korean patients. Determining the need for appropriate DVT prophylaxis is difficult when considering the low incidence of DVT in the Asian population. The aim of this study was to investigate the incidence of DVT occurring 3 months after KT, the DVT occurrence pattern, and risk factors in Korean patients.
New portable system for dental plaque measurement using a digital single-lens reflex camera and image analysis: Study of reliability and validation

Background: The quantification of the dental plaque (DP) by indices has limitations: They depend on the subjective operator′s evaluation and are measured in an ordinal scale. The purpose of this study was to develop and evaluate a method to measure DP in a proportional scale. Materials and Methods: A portable photographic positioning device (PPPD) was designed and added to a photographic digital single-lens reflex camera. Seventeen subjects participated in this study, after DP disclosure with the erythrosine, their incisors, and a calibration scale ware photographed by two operators in duplicate, re-positioning the PPPD among each acquisition. A third operator registered the Quigley-Hein modified by Turesky DP index (Q-H/TPI). After tooth brushing, the same operators repeated the photographs and the Q-H/TPI. The image analysis system (IAS) technique allowed the measurement in mm 2 of the vestibular total tooth area and the area with DP. Results: The reliability was determined with the intra-class correlation coefficient that was 0.9936 (P < 0.05) for the intra-operator repeatability and 0.9931 (P < 0.05) for inter-operator reproducibility. The validity was assessed using the Spearman′s correlation coefficient that indicated a strong positive correlation with the Q-H/TPI rs = 0.84 (P < 0.01). The sensitivity of the IAS was evaluated with two sample sizes, only the IAS was able to detect significant differences (P < 0.05) with the sample of smaller size (n = 8). Conclusions: Image analysis system showed to be a reliable and valid method to measure the quantity of DP in a proportional scale, allowing a more powerful statistical analysis, thus facilitating trials with a smaller sample size.
MPPT controller for a photovoltaic power system based on fuzzy logic

This paper proposes a maximum power point tracking algorithm based on fuzzy logic control for photovoltaic systems, According to the nonlinear characteristic of photovoltaic array [1], it's necessary to find a solution to track the maximum power of the PV system in order to improve its efficiency. The fuzzy logic controller presented in this work provide fast response and good performance against the climatic and load change and uses directly the DC/DC converter duty cycle as a control parameter. Simulation results show that the proposed algorithm can effectively improve the efficiency of photovoltaic array output.
An aboral‐dorsalization hypothesis for chordate origin

Chordates originated from a common ancestor(s) shared with two other deuterostome groups, echinoderms and hemichordates, by creating a novel type of tadpole‐like larva, which was characterized by a dorsal hollow neural tube and notochord. Recent molecular phylogeny supports the notion that echinoderms and hemichordates form a clade named the Ambulacraria and that, among the chordates, cephalochordates are more basal than urochordates and vertebrates. An aboral‐dorsalization hypothesis is proposed to explain how the tadpole‐type larva evolved. Embryological comparison of cephalochordates with nonchordate deuterostomes suggests that, because of limited space on the oral side of the ancestral embryo, morphogenesis to form the neural tube and notochord occurred on the aboral side of the embryo. Namely, the dorsalization of the aboral side of the ancestral embryo may have been a key developmental event that led to the formation of the basic chordate body plan. genesis 46:614–622, 2008. © 2008 Wiley‐Liss, Inc.
Self-report measures of anxiety: Are they suitable for older adults?

Objectives: To assess the performance of four self-report measures of anxiety in an older adult population. Method: Forty older adults with current or previous anxiety symptoms completed four self-report measures of anxiety (Beck Anxiety Inventory, State Trait Anxiety Inventory, Hospital Anxiety and Depression Scale and Visual Analogue Scale) and received an independent diagnostic assessment and rating of anxiety severity. After a minimum of four months, participants were re-assessed on all measures. Results: The self-report measures most suited for anxiety screening and assessing severity when compared to the independent assessment were the Beck Anxiety Inventory (BAI), the anxiety scale from the Hospital Anxiety and Depression Scale (HADS-A) and State Trait Anxiety Inventory-Trait form (STAI-T). However, participants made an unacceptably high number of errors using the STAI-T, making the BAI and HADS-A the most suitable measures for older adults. The Visual Analogue Scale (VAS) performed poorly in both screening and measuring severity. All self-report measures were poor at detecting change as evaluated by the independent assessment. Conclusion: There was no single measure that performed adequately in screening, measuring severity and monitoring changes, suggesting that measures may need to be adapted if they are to be used in an older adult population. The lack of appropriately designed self-report measures with adequate normative data for older people presents a barrier to future research.
Fanconi syndrome and renal failure induced by tenofovir: a first case report.

Although nephrotoxicity of cidofovir and adefovir is well established, no renal side effects have been observed yet with tenofovir, which is the third member of this family. The authors report the case of a patient who had Fanconi syndrome, nephrogenic diabetes insipidus, and acute renal failure during treatment with tenofovir, a nucleotide reverse transcriptase inhibitor that recently has been approved by the Food and Drug Administration for treatment of patients infected with human immunodeficiency virus.
Postoperative multichannel magnetoencephalography in patients with recurrent seizures after epilepsy surgery

Objective – Assessment of usefulness of magnetoencephalography (MEG) as a novel non‐invasive technique in the diagnostic evaluation of patients with recurrent seizures after unsuccessful epilepsy surgery. Material and methods – Seventeen patients in whom epilepsy surgery had failed underwent reevaluation by means of MEG in addition to standard presurgical investigations (EEG, MRI, SPECT, and neuropsychologic testing). Results – Source analysis of interictal epileptic MEG discharges revealed dipole localizations immediately adjacent to the borders of previous resection in 10 of 17 patients. Standard non‐invasive presurgical evaluation suggested epileptogenicity over the general area of previous resection in all patients, but did not provide any detailed spatial localizing data. Invasive EEG recordings confirmed the MEG focus localization in all of 5 patients who were selected for reoperation. Second operation at the site of previous resection achieved complete seizure control in 3 and cessation of tonoclonic seizures in 1 of these patients. Conclusion – MEG may provide useful information in the diagnostic reevaluation of postoperative epileptic patients in whom skull and dura defects produce a “breach effect” which alters non‐invasive and invasive EEG.
Technological uncertainty: Exploring factors in indian start-ups

Technological uncertainty(TU) is often a great challenge and a matter of concern for a decision maker of the firm due to rapid change in the R&D technology and introduction of new technology in the firm's environment. Bigger question remains how we can conceptualize TU, especially in particular environmental context. Literature on TU reveals the need for identifying factors representing TU. This paper identifies the factor structure of TU having dimensions of uncertainty about technology vigilance and uncertainty about product flexibility in dynamically changing firm's environment. Extractions of factors were compared and confirmed using an alternative factor retention criterion `Parallel Analysis'. 600 entrepreneurs, engaged in start-ups from all over India participated in the study. A scale is proposed to be developed and recommended for generalization in multiple industry set-ups. This paper adds to the literature of environmental uncertainty and start-up decision making.
The Natural Selection of Herpesviruses and Virus-Specific NK Cell Receptors

During the co-evolution of cytomegalovirus (CMV) and natural killer (NK) cells, each has evolved specific tactics in an attempt to prevail. CMV has evolved multiple immune evasion mechanisms to avoid detection by NK cells and other immune cells, leading to chronic infection. Meanwhile, the host has evolved virus-specific receptors to counter these evasion strategies. The natural selection of viral genes and host receptors allows us to observe a unique molecular example of “survival of the fittest”, as virus and immune cells try to out-maneuver one another or for the virus to achieve détente for optimal dissemination in the population.
The validity of continuous automated fluid monitoring during endometrial surgery: luxury or necessity?

Thirty‐four consecutive women undergoing endometrial laser ablation, as a treatment of menorrhagia, were recruited to assess the validity of fluid absorption monitoring by a new continuous automated system (AquaSens). The same group of women also had monitoring of fluid absorption carried out by our standard technique of weighing. The intra‐class correlation coefficient for the fluid deficit estimated by AquaSens compared to our standard technique of manually weighing the irrigation bags was 0.98 (95% CI 0.96–0.99). Aquasens therefore provides a valid and non‐invasive method of continuously monitoring fluid deficit amongst patients undergoing operative hysteroscopy procedures, thereby reducing the risk of unexpected fluid absorption and its potentially fatal sequelae.
University of Groningen Comparative roll-over analysis of prosthetic feet

A prosthetic foot is a key element of a prosthetic leg, literally forming the basis for a stable and efficient amputee gait. We determined the roll-over characteristics of a broad range of prosthetic feet and examined the effect of a variety of shoes on these characteristics. The body weight of a person acting on a prosthetic foot during roll-over was emulated by means of an inverted pendulum-like apparatus. Parameters measured were the effective radius of curvature, the forward travel of the center of pressure, and the instantaneous radius of curvature of the prosthetic feet. Finally, we discuss how these parameters relate to amputee gait. & 2009 Elsevier Ltd. All rights reserved.
The Gastroenteropancreatic Neuroendocrine Cell System and Its Tumors: The WHO Classification

Abstract: Although well established in medical terminology, the term carcinoid is no longer adequate to cover the entire morphological and biological spectrum of neoplasms of the disseminated neuroendocrine cell system. Therefore, instead of carcinoid, the WHO classification published in 2000 uses the general terms neuroendocrine tumor and neuroendocrine carcinoma. In this review a classification of gastroenteropancreatic neuroendocrine tumors based on the WHO criteria is described. We also classify and comment on the most important tumor entities. On the basis of localization and of various morphological and biological criteria, we distinguish between benign neuroendocrine tumors, tumors with uncertain malignant potential, and tumors showing low‐grade and high‐grade malignancy.
A low-cost adjustable speed drive for three phase induction motor

This paper describes the development a low-cost adjustable speed drive for three phase induction motor. The system consists of two modules, control, and power. The control module consists of an analog controller (relaxation oscillator) depending on the complexity of the application. For simple processes, resistance adjustment can change the motor speed as necessary. The power module is sized to capacity requirements and motor receiving the corresponding signal, being able to replace depending on the motor, and such Triacs or SCRs. Then, a linear response was obtained through the change of a resistor with low voltage and current THD. For this study, was used squirrel cage induction motor with 4-poles, 2-hp of nominal power and 208-V, 60-Hz.
Contact Lens-related Infectious Keratitis

Infectious keratitis is the most serious complication of contact lens use. Virtually all contact lens wearers are at risk. Initial therapy consists of frequent broad-spectrum fortified antibiotic drops after appropriate laboratory workup. Pseudomonas and Acanthamoeba species are the most important causes of contact lens-associated ulcers. Acanthamoeba keratitis produces significant ocular morbidity, and treatment is not always effective. Recent studies have provided new insights regarding the incidence, risk factors, and pathogenesis of contact lens-related infectious keratitis. Extended-wear soft contact lens wearers are at greatest risk. With our present understanding of the pathogenesis and risk factors of contact lens-related infectious keratitis, daily-wear schedules are strongly advised. Even under the best of lens care conditions, infectious keratitis may still occur. It is therefore imperative that patients be informed to remove their lenses and seek medical evaluation if any discomfort develops.
Growth of carbon nanoflakes from nitric acid oxidized electric arc-discharged CNTs and its gas sensing properties

This paper presents synthesis, characterization and gas sensing properties of two dimensional nanostructures i.e. carbon nanoflakes (CNFs) grown by electro-phoretic deposition(EPD) on steel substrate using nitric acid refluxed electric arc synthesized carbon nanotubes(CNTs). Formation of CNFs has been confirmed by XRD and Raman spectra. Optical band gap measurement has been performed by UV-Vis spectroscopy. The morphology of CNFs has been studied via SEM. The EPD film has been characterized for gas sensing. The sensor responded to relatively low concentrations of liquefied petroleum gas (LPG) thus suggesting high-quality CNFs are useful for gas sensors. Sensor has shown maximum response at 200 °C.
A new performance analysis scheme for frequency correlated diversity in Rayleigh fading channels

The correlated frequency diversity may be used in future mobile communication to maintain both the spectral efficiency and the reliabilities. In this paper, a new method of analyzing system performance for correlated frequency diversity is proposed. As for the correlated frequency diversity, the correlation exists not only between carriers, but also the fading envelope corresponding to different carriers. In our method, after a serial of transformations, the correlated fading can be converted into independent Rayleigh fading, which means it is simple to obtain the system performance. In this paper, this method is investigated based on the MRC (maximal ratio combining) reception at the receiver. The analysis and simulation results prove the effectiveness and simpleness of this proposed method.