Miracle-dz/UniFAR-FTUs huggingface dataset:
Study on the attitude control for High-speed Rotary Missile based on neural networks

In the thesis, a new attitude control methods with neural network is set up for forcasting High-speed Rotary Missile. When considering the fix-errors, output equation is complex and nonlinear. The system is identified with BP neural network based on LM algorithm. Simulation results show that these attitude control methods can implement efficiently precise attitude control of rotary missile and identified effectively. It is possible that the integrated navigation system will be used in theory.
Portable single-channel NIRS-based BMI system for motor disabilities' communication tools

A portable near-infrared spectroscopy (NIRS) -based brain-machine Interface (BMI) system featuring single-channel probe, BMI controller and Infrared-emission apparatus was developed. As a switching technology for external devices, the threshold logic was proposed, which detects the blood volume change in the operator's frontal lobe. Experiments showed that the operator was able to change the TV programs or get forward the toy robot within 16 s (the mean is 11.77 s and the standard deviation is 2.35 s) after the mental calculation. In addition, the menu selection program was proposed for motor disabilities and the preliminary test showed that he could successively select the sentence from several candidates. It was shown that this system would provide the external device's control capabilities for motor disabilities.
Protein Tyrosine Phosphatase Profiling Analysis of HIB-1 B Cells during

A number of evidence have been accumulated that the regulation of reversible tyrosine phosphorylation, which can be regulated by the combinatorial activity of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), plays crucial roles in various biological processes including differentiation. There are a total of 107 PTP genes in the human genome, collectively referred to as the “PTPome. ” In this study, we performed PTP profiling analysis of the HIB-1B cell line, a brown preadipocyte cell line, during brown adipogenesis. Through RT-PCR and real-time PCR, several PTPs showing differential expression pattern during brown adipogenesis were identified. In the case of PTP-RE, it was shown to decrease significantly until 4 days after brown adipogenic differentiation, followed by a dramatic increase at 6 days. The overexpression of PTP-RE led to decreased brown adipogenic differentiation via reducing the tyrosine phosphorylation of the insulin receptor, indicating that PTP-RE functions as a negative regulator at the early stage of brown adipogenesis.
Corticocortical and collateral thalamocortical connections of postcentral somatosensory cortical areas in squirrel monkeys: a double-labeling study with radiolabeled wheatgerm agglutinin and wheatgerm agglutinin conjugated to horseradish peroxidase.

Experiments were performed to determine whether thalamic neurons send collaterals to more than one subdivision of postcentral somatosensory cortex, and to evaluate the fidelity of somatotopic connections between cortical representations of the body surface. After microelectrode recordings identified the locations of the representations of the fingertips along the border of area 3b with area 3a and along the border of area 1 with area 2, one tracer, tritiated N-acetyl wheatgerm agglutinin ([3H]WGA), was injected into the rostral representation at the 3a-3b border, and another, wheatgerm agglutinin conjugated to horseradish peroxidase (WGA:HRP), was injected into the caudal representation at the 1-2 border. The results indicate that three thalamic regions are interconnected with both border zones. Regions of overlapping retrograde and anterograde label included the ventromedial portion of the lateral division of the ventroposterior nucleus (VPL), which is known to represent the digits; the medial extent of a dorsal capping zone of VPL that we term the ventroposterior superior nucleus (VPS); and the anterior pulvinar (Pa). Cells labeled with one or the other tracer, as well as cells labeled with both tracers, were found in VPL, VPS, and Pa. Our procedures necessarily underestimated the numbers of cells projecting to both rostral and caudal injection zones, but at least 15-20% of VPL and 20-40% of VPS neurons that were autoradiographically labeled appeared to have such collaterals. While only a few cells in Pa were autoradiographically labeled from injections at the 3a-3b border, the presence of several double-labeled cells suggests that at least some Pa neurons project to both injected zones. By relating the present results to those from studies where connections were determined for single architectonic fields, we conclude that many neurons in VP project to both areas 3b and 1, and that many neurons in VPS project to both areas 3a and 2. In addition, both areas 3a and 2 appear to have interconnections with Pa. Connections of Pa with area 2 have only recently been reported (Pons and Kaas, in press), and connections of Pa with area 3a have not been described. The results imply that, in part, the same information from cutaneous receptors is relayed to areas 3b and 1, and the same information from deep receptors is relayed to areas 3a and 2. (ABSTRACT TRUNCATED AT 400 WORDS)
Avoiding ‘data snooping’ in multilevel and mixed effects models

Summary. Multilevel or mixed effects models are commonly applied to hierarchical data. The level 2 residuals, which are otherwise known as random effects, are often of both substantive and diagnostic interest. Substantively, they are frequently used for institutional comparisons or rankings. Diagnostically, they are used to assess the model assumptions at the group level. Inference on the level 2 residuals, however, typically does not account for ‘data snooping’, i.e. for the harmful effects of carrying out a multitude of hypothesis tests at the same time. We provide a very general framework that encompasses both of the following inference problems: inference on the ‘absolute’ level 2 residuals to determine which are significantly different from 0, and inference on any prespecified number of pairwise comparisons. Thus, the user has the choice of testing the comparisons of interest. As our methods are flexible with respect to the estimation method that is invoked, the user may choose the desired estimation method accordingly. We demonstrate the methods with the London education authority data, the wafer data and the National Educational Longitudinal Study data.
Apoptosis as a mechanism of keratinocyte death in toxic epidermal necrolysis

Summary Toxic epidermal necrolysis (TEN) and Stevens‐Johnson syndrome (SJS) are life‐threatening diseases characterized by extensive epidermal destruction. The aim of our study was to investigate apoptosis in keratinocytes of patients with TEN and TEN/SJS overlap syndrome. Keratinocytes from TEN patients were found to undergo extensive apoptosis. These results suggest that cell destruction in TEN occurs as a result of apoptosis. Our findings suggest that apoptosis inhibitory agents may play an important part in the therapeutic strategy of TEN.
Protective immunity and pathology induced by inoculation of mice with different subcellular fractions of Trypanosoma cruzi.

Mice were immunized with subcellular fractions obtained by differential centrifugation from epimastigotes of Trypanosoma cruzi (Tulahuén strain). In a chronic model of Chagas' disease, they were challenged each with 25 bloodstream trypomastigotes. Non-immunized, non-challenged and non-immunized challenged animals were kept as controls. Among the challenged mice, those immunized with 105,000 g pellet (Mc) and 105,000 g supernatant (Cs) fractions presented positive xenodiagnosis, myocarditis and myositis similar to those shown by non-immunized challenged controls. The fractions enriched in flagella, the 5000 g pellet (P5) and the flagellar fraction (F) resulted in fewer animals with positive xenodiagnosis and in hosts partially protected from the development of myocarditis. In the absence of infection, Mc and Cs induced an intense myocarditis while F induced mild lesions similar to those found in the controls. P5 caused a myocarditis intermediate between that elicited by Mc and that in the controls. 50% of the animals immunized with Cs presented pathological electrocardiograms in the absence of challenge. The animals immunized with F and P5 and challenged were protected against the development of pathological electrocardiograms, whereas those immunized with Mc and Cs behaved like the non-immunized controls. The immunized, non-challenged animals presented anti-T. cruzi IgG antibodies, with titres which were lower than those shown by the immunized and challenged mice. --The results show the possibility of obtaining tissue lesions with antigenic preparations of T. cruzi in the absence of infection, and suggest that the mechanisms involved in the generation of myocarditis and electrocardiographic alterations are probably different, since these pathologies can be elicited by different subcellular fractions. Among the antigenic components of the parasite, the flagellar fraction gave the best immunoprotective properties, with little or no immunoaggressive effects.
Evolutionary Change in Product Management: Experiences in the Car Rental Industry

Car rental companies offer customers various combinations of car types, rental periods, and pickup and return locations, as well as temporary insurance and refueling options. Hertz developed its yield management system YMS to help decide the availability of these combinations of products over time. The YMS integrates information management technology, sophisticated operations research techniques, and information from existing Hertz decision support models that solve the closely-related problems of pricing, fleet planning, and fleet deployment.
Kinetics Study for the Recombinant Cellulosome to the Degradation of Chlorella Cell Residuals

In this study, lipid-deprived residuals of microalgae were hydrolyzed for the production of reducing sugars by using the recombinant Bacillus cellulosome, carrying eight genes from the Clostridium thermocellum ATCC27405. The obtained cellulosome was found to exist mostly in the broth supernatant with a cellulosome activity of 2.4 U/mL. Furthermore, the Michaelis-Menten constant (Km) and Vmax of cellulosome were found to be 14.832 g/L and 3.522 U/mL. The activation energy of the cellulosome to hydrolyze microalgae LDRs was calculated as 32.804 kJ/mol. Keywords—Lipid-deprived residuals of microalgae, cellulosome, cellulose, reducing sugars, kinetics.
A New Data Anonymization Technique usedFor Membership Disclosure Protection

Several anonymization techniques, like generalization and bucketization, have been intended for privacy preserving microdata publishing. current work has shown that generalization loses significant amount of information, particularly for high-dimensional data. on the other hand, Bucketization does not prevent membership disclosure and does not apply for data that do not have a clear separation between quasi-identifying attributes and sensitive attributes. In this paper, we present a new technique called slicing, in that data is partition into both horizontally and vertically. We demonstrate that slicing preserves better data utility than generalization and can be used for membership disclosure protection. Another main advantage of slicing is that it can handle high-dimensional data. We illustrate how slicing can be used for attribute disclosure protection and build up an efficient algorithm for computing the sliced data that obey the l-diversity requirement. Our workload experiments verify that slicing preserves better utility than generalization and is more effective than bucketization in workloads involving the sensitive attribute. Our experiments also show that slicing can be used to prevent membership disclosure.
Absence of CD69 expression on peripheral eosinophils in episodic angioedema and eosinophilia

A 45‐year‐old woman with episodic angioedema and eosinophilia is presented. CD69, which is one of the surface antigens of activated eosinophils, was not expressed on the peripheral eosinophils in this patient, in contrast to hypereosinophilic syndrome. This suggests that CD69, which is not dependent on eosinophil density, may be another useful activation marker of eosinophils to distinguish episodic angioedema and eosinophilia from hypereosinophilic syndrome. © 1996 Wiley‐Liss, Inc.
An 800MHz embedded DRAM with a concurrent refresh mode

The embedded DRAM employs a transfer gate formed from a 22A Gox, 1.5V logic IO device resulting in 3.2ns cycle and latency. A concurrent refresh mode and a refresh scheduler prove /spl ges/:99% memory availability for a 64/spl mu/s cell retention time. In-macro circuitry supports redundancy allocation during 800MHz multi-banking operation.
Disabling musculoskeletal pain and its relation to somatization: a community-based postal survey.

BACKGROUND Somatization (a tendency to report distress from somatic symptoms) is a little studied, but potentially important, confounder and effect modifier in occupational studies of musculoskeletal disease. AIMS To assess the role of somatization as a risk factor for disabling regional pain. METHODS A questionnaire was mailed to 4998 subjects of working age. Questions were asked about chronic and disabling pain in the past 12 months affecting the arm, low back, knee or combinations of these sites. Distress from physical symptoms was assessed using elements of the Brief Symptom Inventory and mental well-being was assessed using the short-form 36 (SF-36). Associations were examined by modified Cox regression and expressed as hazard ratios (HRs) with 95% confidence intervals (CI). RESULTS Among 2632 responders, 24% reported chronic pain and 25% disabling pain at one or several sites. Risk of chronic or disabling pain increased strongly according to the number of somatic symptoms reported as bothersome. For example, the HR for chronic upper limb pain in those distressed by > or =2 somatic symptoms in the past 7 days versus none was 3.9 (95% CI 2.9-5.3), and that of disabling upper limb pain was 5.8 (95% CI 4.1-8.3). Similar patterns were found for the low back and knee, and there was a gradient of increasing risk according to the number of sites with disabling pain. In comparison, associations with SF-36 mental well-being score were weaker. CONCLUSION Somatizing tendency should be evaluated as a possible confounder or effect modifier in studies of occupational risk factors for musculoskeletal pain.
Posttranscriptional Events in the Expression of Myelin Protein Genes a

A number of posttranscriptional events may be involved in regulating the expression of the myelin protein genes. One such event in the expression of the myelin basic protein (MBP) gene is the translocation of MBP mRNAs from oligodendrocyte cell bodies to their processes. This translocation can be observed in vivo and in primary mixed glial cell cultures. In jimpy brains the translocation of MBP mRNA appears to be disrupted, so that most of the mRNA remains associated with cell bodies. This apparent failure of translocation may account for the lack of incorporation of newly synthesized MBP into jimpy myelin. In quaking myelin, where MBP assembly is also defective, translocation appears to be normal, suggesting that incorporation of MBP into the membrane also is regulated posttranslationally. We have identified a number of the structural features of MBP mRNAs that influence the efficiencies with which they are translated and may be involved in regulating the levels of individual MBP produced. We also found that glucocorticoids stimulate the translation of MBP and PLP mRNAs and inhibit the translation of CNP mRNA in cell-free systems. Our results suggest that this pattern of translational regulation may be physiologically meaningful, especially during maturation of myelin. The mechanism by which the steroids modulate translation of these messages appears to be novel. Analysis of the effect of steroids on cRNAs produced from engineered MBP cDNA constructs has permitted the identification of a nine nucleotide element involved in this steroid modulation within the 5' untranslated region of the MBP mRNA.
Un essai contrôlé randomisé: effet du port de chaussures à talons hauts sur le squelette appendiculaire inferieur

Introduction Véritable attribut de la féminité, le port de chaussures à talons est devenu une exigence professionnelle dans certaines structures des pays en développement comme le Bénin. L'objectif de ce travail est de déterminer les effets spécifiques du port de chaussures à talons hauts sur le squelette appendiculaire inférieur. Méthodes Des examens radiographiques de face et de profil de la cheville et du genou ont été effectués sur 122 femmes volontaires, âgées en moyenne de 25,09 ± 1,34 ans et ayant les genu varum qui ont participé à cette étude. Résultats Les résultats ont indiqué une augmentation significative de l’écart inter malléolaire, de l’écart inter condylien, de l'angle antérieur du pied et de l'angle fémoro-patellaire. Une diminution significative de l'angle postérieur du pied a été constatée. Conclusion Le port de chaussures à talons hauts est l'une des causes de la gonarthrose, des troubles des articulations de la cheville et du pied.
The undecidability of formal definitions in the theory of finite groups

In this paper a set of explicit expressions for a family of finite groups will be constructed in the language of Zermelo-Fraenkel plus the Axiom of Choice set theory in such a way that there is no general procedure to decide whether a given expression of this set is representing a finite solvable group or not.
The Addiction Severity Index as a screen for trauma and posttraumatic stress disorder.

OBJECTIVE The Addiction Severity Index (ASI) includes items to assess patients' history of trauma (physical or sexual). The goal of this study was to assess the sensitivity and specificity of those questions in relation to the Trauma History Questionnaire (THQ), a more thorough measure of lifetime trauma and, in addition, to an actual posttraumatic stress disorder (PTSD) diagnosis. METHOD At the start of treatment cocaine dependent outpatients (N = 110, 65.5% male) were assessed on the ASI, the THQ and a PTSD symptom checklist as part of a multisite clinical trial. RESULTS Specificity of the ASI questions was higher than sensitivity for both sexual trauma (specificity = .96, sensitivity = .46) and physical trauma (specificity = .71, sensitivity = .50), while for PTSD the sensitivity of the ASI (.91) was higher than its specificity (.43). Other findings indicated that patients were more likely to report trauma on the THQ than on the ASI (which may be due to the self-report format of the THQ); that the ASI was better at assessing sexual than assessing physical trauma; and that the higher the number of ASI trauma items endorsed, the more likely was the PTSD diagnosis. Finally, PTSD patients had greater severity than non-PTSD patients on other ASI items (e.g., psychological severity, need for treatment). CONCLUSIONS The ASI trauma questions show stronger utility as a screen for PTSD than for trauma. Results of the study are discussed in light of ways to modify the ASI to screen more accurately for trauma, clinical implications, and limitations of the study method.
A CMOS Differential Difference Amplifier with Reduced Nonlinearity Error of Interpolation for Interpolating ADCs

In this paper, the nonlinearity error induced by interpolation amplifier in interpolating analog-to-digital converters (ADCs) is analyzed, and a new differential difference amplifier (DDA) with well restrained nonlinearity error is presented. Its highly steady common-mode output voltage makes it especially suitable for differential interpolating ADCs. The amplifier is designed in a 0.35mum standard CMOS process with a single 3.3V supply. Simulated results show that this amplifier achieves a steady common-mode output in a wide common-mode input range from 0.85V to 2.45V without demanding complex circuitry. The amplifier settles in 4.8ns to an accuracy of 0.01% and dissipates a total power of 398.38muW
Compound synapses within the GABAergic innervation of the auditory inner hair cells in the adolescent mouse

Ultrastructural investigation of the γ‐aminobutyric acid (GABA) component of the inner spiral bundle in adolescent mice revealed a pathway of glutamic acid decarboxylase (GAD)‐positive and ‐negative fibers and vesiculated endings that contact inner hair cells and their afferents through a complex of axosomatic and axodendritic synapses. Ultrastructural details were investigated by using conventional electron microscopy. Several synaptic arrangements were observed: Main axosomatic synapses form between vesiculated endings and individual or adjoining inner hair cells (interreceptor synapses). Spinous synapses form on long, spinelike processes that protrude from inner hair cells to reach distant efferent endings. The efferent endings associate with inner hair cells and their synaptic afferents through compound synapses—serial, “converging,” and triadic—otherwise characteristic of sensory relay nuclei. Serial synapses form by the sequential presynaptic alignment of the efferent→receptor→afferent components. Converging synapses result from the simultaneous apposition of a receptor ribbon synapse and a presynaptic efferent terminal on a recipient afferent dendrite. Triadic synapses comprise a vesiculated efferent ending in contact with an inner hair cell and with its synaptic afferent. Additionally, efferent endings may form simple axodendritic and axoaxonal synapses with GAD‐negative vesiculated endings. The combination of different synaptic arrangements leads to short chains of compound synapses. It is assumed that these synaptic patterns seen in the adolescent mouse represent adult synaptology. The patterns of synaptic connectivity suggest an integrative role for the GABA/GAD lateral efferent system, and imply its involvement in the pre‐ and postsynaptic modulation of auditory signals. J. Comp. Neurol. 377:423–442, 1997. © 1997 Wiley‐Liss, Inc.