Miracle-dz/UniFAR-FTUs huggingface dataset:
Patient Advocacy for Health Care Quality: Strategies for Achieving Patient-Centered Care

As a contribution to the emerging healthcare quality movement, Patient Advocacy for Healthcare Quality: Strategies for Achieving Patient-Centered Care is distinct from any others of its kind in its focus on the consumer's perspective and in its emphasis on how advocacy can influence change at multiple social levels. This introductory volume synthesizes patient advocacy from a multi-level approach and is an ideal text for graduate and professional students in schools of public health, nursing and social work.
The Psychological Impact of Breast Cancer on The Every Day’s Life through The Eyes of Survivors

Background: The incidence of breast cancer in Eastern Country is unexpectedly increasing more than any other types of cancer in women. The purpose of this study was to explore and describe how breast cancer affects well-being of affected women, particularly their physical, emotional, personal and social aspects. Method: For the present study thirty-nine women were interviewed at different stages of diseases. Thirteen patients were recently diagnosed with breast cancer, ten were undergoing chemotherapy, nine were on follow-up and rest consisted of socially rejected once by others for their disease. All participants reported their experience through structured interview. A constructive grounded theory approach was used where includes different areas of domains of problems having impact on daily life. Results: Our study showed that, the reactions of the patients, when they were first informed about their disease is usually the thought of death. After first chemotherapy, behavioral changes were observed, in the form of lack of awareness about side effects. Social factors also play an important role in developing psychological stress. Conclusion: Various stages of diagnostic treatment pathway give rise to a range of unique and diverse influences on physical, emotional social and psychological well-being.
Psychological Impact of various Therapeutic Modalities in Childhood Malignancy

Background: The purpose of the study is to evaluate and compare the psychological impact of various therapeutic modalities in pediatric cancer by comparing them to healthy children across age groups.Methods: The semi-structured and the Mini International Neuropsychiatric interview (M.I.N.I Kids Test) were administered to 80 children including 40 cancer patients and 40 healthy children. Results: CNS tumors were the most commontumor 47.5% followed by heamatological malignancies 35% and Non CNS solid tumors 17.5%. About two thirds of the sample reported social problems followed by school problems in 57.5% of cases. By analyzing the mood changes, there was significant depression, anxiety disorders, panic attacks and separation anxiety between the patients and the control (p= <0.001). The patients had also significant lack of attentionand stubbornness (p=<0.001). These problems did not show any difference between sex except for depression and social worries which were more in girls. These symptoms did not show any difference as regard receiving or not chemotherapy, radiotherapy or combination. Conclusion: The psychological problems were more evident in cancer patients compared to healthy children and was higher than developing countries. The present study highlighted the need of a health care team and integration of a comprehensive psychological support in the treatment plan in Egypt. This will improvequality of life and reduce the burden of treatment.
The effect of an isotonic weight-training program upon bone density and selected indices of bone turnover in early postmenopausal women /

Oversize materials (e.g., maps, drawings, charts) are re­ produced by sectioning the original, beginning at the upper left-hand corner and continuing from left to right in equal sections with small overlaps. Each original is also photographed in one exposure and is included in reduced form at the back of the book. These are also available as one exposure on a standard 35mm slide or as a 17" x 23" black and white photographic p rin t for an additional charge.
Effects of frying condition on physicochemical properties of palm olein-olive oil blends.

The main objective of present study was to investigate the effects of frying conditions (i.e. the type of frying oil and frying time) on physicochemical properties of palm olein-olive oil blends (POo: Oo, 75:25 and 50:50 w/w) compared to the pure palm olein (100% w/w). The frying process of French fries was performed in duplicate at 180 ± 5 oC for 5 consecutive days. The physicochemical properties of the frying media namely the fatty acids composition (FAC), iodine value (IV), free fatty acid (FFA) and color were considered as response variables. The present study clearly indicated that the frying performance of palm olein significantly (p < 0.05) improved by the blending of palm olein (Po) with the olive olein (Oo). As shown in the results, there was a significant (p < 0.05) positive correlation between FFA and color. The present work suggested that partial replacement of palm olein with olive oil provided the oil blends (POo: Oo, 75:25 and 50:50 w/w) with more desirable functional properties for the human health due to the high proportion of monounsaturated to saturated/polyunsaturated fatty acids.
Influencia de la condición corporal y producción de leche sobre el comportamiento reproductivo de vacas lecheras mestizas

The influence of the body condition (CC) to the childbirth and the production of the milk before the 65 days, or before the first estrous pospartum, on the restart of the activity ovarian recurrent luteal (AOLC) and the number of silent estrous (ES), before the first behavior estro and period childbirth-first observed estro, they were evaluated to the beginning of the pospartum in 36 mestizo cows HxC. The cows were fed in different form in the prepartum period to settle down itt lists of body condition (ECC) among 2.0 – 5.0 to the chidbirth, considering as ECC 2.0 – 2.9 = low CC; 3.0 – 3.9 =CC mediates ; and 4.0 – 5.0 = CC discharge. In the xperimet a desing was used
Cell Communication and Signaling

The CCN family of genes consists presently of six members in human (CCN1-6) also known as Cyr61 (Cystein rich 61), CTGF (Connective Tissue Growth Factor), NOV (Nephroblastoma Overexpressed gene), WISP-1, 2 and 3 (Wnt-1 Induced Secreted Proteins). Results obtained over the past decade have indicated that CCN proteins are matricellular proteins, which are involved in the regulation of various cellular functions, such as proliferation, differentiation, survival, adhesion and migration. The CCN proteins have recently emerged as regulatory factors involved in both internal and external cell signaling. CCN3 was reported to physically interact with fibulin-1C, integrins, Notch and S100A4. Considering that, the conformation and biological activity of these proteins are dependent upon calcium binding, we hypothesized that CCN3 might be involved in signaling pathways mediated by calcium ions. In this article, we review the data showing that CCN3 regulates the levels of intracellular calcium and discuss potential models that may account for the biological effects of CCN3.
Rosewood of Madagascar: Between democracy and conservation

In 2009 an estimated 52,000 tonnes of precious wood from ca. 100,000 rosewood and ebony trees was logged in north - east Madagascar, one third originating from Marojejy National Park and its environs, the remainder from in and around Masoala National Park. At least 500,000 additional trees and many miles of vines were cut to make rafts to transport the heavy ebony and rosewood logs. Approximately 36,700 tonnes were shipped in 1,187 containers, almost all to China, for a total export sale price estimated at $ US 220 million. In the SAVA region, members of the timber syndicate pocketed 76 % of this whereas the State collected just $ US 15.3 million. Of the three main companies that transported rosewood from Vohemar, Delmas benefited most; three banks also facilitated the illegal timber trade. Fraud is perpetrated by the syndicate and government administrators along every step in Madagascar’s precious timber trade in a coordinated effort to maximize profit and minimize taxes and fines. Poor governance and a lack of clarity in forest regulation have facilitated timber trafficking and undermined judicial control; during at least three periods (1992, 2006 and 2009 - 2010) escalation of rosewood exportation has been facilitated by government decrees issued prior to elections or during difficult political times, in each instance accompanied by ‘exceptional’ government orders allowing a few powerful operators to export massive quantities of wood – all part of a carefully orchestrated cycle. The near-silence of donors and NGOs is linked to their loss of influence following suspension of all but humanitarian aid since 17 March 2009.
Local microbiologic profile in venous leg ulcer and topic treatment with natural or pharmaceutical products

Venous leg ulcers represent a major clinical problem, because of chronic evolution and difficulties to achieve healing. The ulcer is the most undesirable consequence of chronic venous insufficiency and requires a complex treatment (general and local). Local wound care depends on many factors, including infection of the ulcer. The aim of this study was to evaluate the bacterian presence in lesion and the impact of various germs on clinical evolution. Our study aims to assess the opportunity of antibiotherapy (systemic or local) or anothers antimicrobial agents. We studied 40 patients (admitted in Surgical Clinic I Timisoara) with infected leg ulcers. The microbiologic samples were collected to identify types of germs and sensibility to antibiotics. We considered that very useful to evidence multiresistant-germs (like methicilinoresistant stafilococ). Systemic antibiotherapy is recommended in infected ulcers, not in bacterian colonisation. Topic antibiotic did not prove the efficacy. Worldwide, patients receveid local antibacterial products (like medical honey or herbs extracts) for wound care. The results depends on many factors, but especially on pathogenic treatment of venous chronic disease.
Preliminary study on the degradation of seven organophosphorus pesticides in bovine milk during lactic acid fermentation or heat treatment.

Bovine milk was spiked with seven organophosphorus pesticides, denthion, dimethoate, malathion, methyl parathion, monocrotophos, phorate and trichlorphon, and subjected to heat treatment at 63, 80 and 100°C or lactic acid fermentation at 42°C with commercial directed vat set (DVS) starters to investigate the degradation kinetics of the pesticides in bovine milk during heat treatment and yoghurt processing. The pesticides spiked were extracted from the prepared samples, purified and analyzed with gas chromatograph technique. Then the kinetic parameters of degradation of them were calculated accordingly. Comparing this to that of the pesticides in the bovine milk heated at 42°C, the degradation of the pesticides in the bovine milk during yoghurt processing was found to be totally accelerated by the starters of lactic bacteria applied, because the half live periods of six pesticides decreased except for malathion, and two commercial DVS starters which showed different effects somewhat on the degradation of the pesticides. Analysis results also indicated that the pesticides degraded faster at higher temperature in bovine milk during heat treatment; and among the pesticides methyl parathion and phorate were the most unstable and stable one. Heat treatment and lactic acid fermentation could reduce the level of organophosphorus pesticide in dairy products. Key words: Bovine milk, organophosphorus pesticide, degradation, yoghurt, starter, heat treatment.
The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation

Phylogenetic footprinting is an evolutionary tool used for the identification of functional elements in selected genomes. This method relies on the search for similarities among ancestrally related sequences and has been widely used to identify cis-regulatory elements in non-coding genomic regions. Conserved non-coding elements (CNEs) have been shown to be crucial for controlling gene transcription in vertebrate genomes. Here we present practical guidelines for discovering new cis-regulatory elements using phylogenetic footprinting and discuss pros and cons of different approaches for the functional characterization of these elements. In addition, we present two case studies to provide practical examples of how this powerful technique is used. The first case study illustrates the in silico identification of the Myostatin gene promoter conserved in vertebrates and its biological validation. The second case study describes the search for cis-regulatory elements of the Raldh2 gene and demonstrates the conserved biological function of an intronic CNE responsible for modulating the gene activity in the embryonic dorsal spinal cord in vertebrates. The comparison of these two case studies highlights the similarities and differences regarding bioinformatic strategies and validation methods for the identification and functional characterization of promoters and distal cis-regulatory elements (enhancers/silencers).
Análise da similaridade florística entre florestas do Alto Rio Xingu, da Bacia Amazônica e do Planalto Central

Recent studies have showed that the phytogeographic identity of the Upper Xingu River is as Seasonal Evergreen Forest. The region has peculiar physical and floristic characteristics, located at the contact area between the rain forest and the Brazilian Savannah (Cerrado). This study shows the floristic similarity between deciduous and semideciduous seasonal forests, cerrado of Middle Brazil and Amazonian tropical rain forests, aiming to interpret the relationship of the Seasonal Evergreen Forest of the Upper Xingu with one of these formations. Thirty-two lists of arbustive-arboreal species were taken from floristic and phytosociologic studies. The floristic similarity was estimated by Jaccard's index and the construction of dendrogram based on group mean values. The analysis of similarity allowed the identification of the clear floristic distinction between the Cerrado and the Amazon Forest biomes, as well as the areas of ecological tension between these biomes. The areas of seasonal evergreen forest were more similar to the monodominant semideciduous seasonal forest, which may be a consequence of their location in the ecotone between the Cerrado and the Amazon Forest. The low similarity between the Seasonal Evergreen Forest and the other forest types confirme the unique flora possessed by this phytophysiognomy, that demonstrates its recognition in a region considered as the transition area.
Clinical efficacy of injection astragalus polysaccharide on treatment primary live cancer patients.

Objective To investigate the clinical efficacy of injection astragalus polysaccharide on treatment primary liver cancer patients.Methods From March 2007 to March 2008,96 primary liver cancer patients with che motherapy randomly divided into conventional chemotherapy group(A) and Astragalus polysaccharide injection group(B). Clinical efficacy of two groups was compared.Results Injection of Astragalus Polysaccharide primary liver cancer tumor and AFP had a noticeable change in value.Conclusion Astragalus polysaccharide for primary liver cancer have a significant role in the treatment and can improve the efficacy of chemotherapy drugs.
Light And Electron Microscopic Neuropathology of Slow Virus Disorders

Transmissible Amyloidoses of the Brain ( D.C. Gajdusek). Pathogenesis of Unconventional Slow Virus Infections (R.I. Carp, R.J. Kascak, and R. Rubenstein). The Molecular Biology of Transmissible Spongiform Encephalopathy (Infectious Cerebral) Amyloidosis (P. Brown). Models of Slow Viruses (P.P. Liberski). An Overview of Neuropathology of the Slow Unconventional Virus Infections (P.P. Liberski and H. Budka). Natural Scrapie (P.P. Liberski). The Spongiform Vacuole-The Hallmark of Slow Virus Diseases (P.P. Liberski, R. Yanagihara, and D.C. Gajdusek). Putative Morphogenesis of Vacuoles from Abnormal Configuration of Plasma Membranes(P.P. Liberski). Astrocytic Changes (P.P. Liberski, D.C. Guiroy, R. Yanagihara, G.A.H. Wells, and D.C. Gajdusek). Immunohistochemistry of Astrocytic Reaction (P.P. Liberski, V. Nerurkar, R. Yanagihara, and D.C. Gajdusek). Microglia in Scrapie (H.M. Wisniewski, J. Wegiel, and P.B. Kozlowski). Neuroaxonal Dystrophy in Unconventional Slow Virus Desease (P.P. Liberski, R. Yanagihara, H. Budka, and D.C. Gajdusek). The Amyloid Plaque (P.P. Liberski, D.C. Guiroy, E.S. Williams, R. Yanagihara, P. Brown, and D.C. Gajdusek). Neuronal Degeneration in Unconventional Slow Virus Disorders (P.P. Liberski, R. Yanagihara, G.A.H. Wells, and D.C. Gajdusek). Tubulovesicular Structures (P.P. Liberski, H. Budka, R. Yanagihara, C.J. Gibbs, Jr., and D.C. Gajdusek). Scrapie-Associated Fibrils (P.P. Liberski and P. Brown). Index.
Urban and rural health chartbook

In the operation of a conventional coke oven battery, a target flue temperature for each oven group is set on the basis of details of coal charge consisting of the weight, the particle size, the moisture content, the volatile matter content and the timing of charging of the coal charge, so as to achieve a target net coking time and a target soaking time given by a coke production schedule. Then, the temperature is measured for individual flues at certain intervals of time and deviations of thus measured flue temperatures from said target flue temperature are calculated by computer, to set a flow rate and a calorific value of the fuel gas for each oven group. A stack draft is set and controlled by computer so that an optimum combustion may take place in response to changes in the flow rate and the calorific value of the fuel gas. Said target flue temperature is furthermore bias-corrected with the use of a mean measured flue temperature, measured net coking times, measured soaking times and the details of coal charge corresponding thereto.
Carcass pH and color of Horro rams under different management practices at Ambo University, Ethiopia

This study was conducted to evaluate and determine the carcass pH and color of Horro rams under different management practices at Ambo University. A total of 24 Horro rams were randomly assigned to the following three treatments: T1 (Day 1 rest before slaughter), T2 (Rhodes hay ad libitum) and T3 (Rhodes hay ad libitum + 400 g concentrate per head/day). Carcass pH was determined at 15 min, 24, 48, and 72 h post slaughter using pH Meter. Data were analyzed using the General linear model procedures of Statistical Analysis System Software 9.2 (SAS, 2009). The ultimate carcass pH of concentrate supplemented Horro rams (pH24 = 5.67) was lower (P 62%) reported that carcass color was bright red for supplemented Horro rams and red color for those fed on Rhodes hay ad libitum and slaughtered immediately after one day rest of transportation. Carcass darkness/discoloration was not observed up to four days post slaughter from values of carcass pH, color estimation of this experiment and from comparisons of carcass pH measures with values in the literatures. Concentrate supplementation had significant and positive influence on carcasses pH and color of Horro rams. This study disproved the dispute or claim about the problem of early darkening of carcasses of highland animals. Thus, management practices like optimum feeding along sufficient rest after transportation would improve the carcass pH and color. Key words: Carcass, pH, color, concentrate, Horro lambs.
The formation of chromatin domains: a new model

In spite of the recent advances in the field of chromatin architecture1,2, the formation mechanism of chromatin domains, TADs, the topologically associating domains, and LADs, the lamina associated domains, is still an open problem. While previous models only dealt with TADs and essentially relied on the architectural proteins CTCF and cohesin, the model presented here concerns both TADs and LADs and is primarily based on the corresponding DNA sequences, the GC-rich and GC-poor isochores, more specifically on their newly discovered 3-D structures. Indeed, the compositionally homogeneous GC-poor isochores were shown to be locally stiff because of the presence of interspersed oligo- Adenines4,5, whereas the compositionally heterogeneous GC-rich isochores were found to be peak-shaped and characterized by increasing gradients of GC and of interspersed oligo- Guanines. In LADs, oligo-Adenines induce local nucleosome depletions4,5 that are responsible for a wavy structure well adapted for interaction with the lamina. In TADs, the increasing GC levels and increasing oligo-Guanines of the isochore peaks are responsible for a decreasing nucleosome density5,6, a decreasing supercoiling7 and an increasing accessibility8. These factors mould the loops of “primary TADs”, that lack self-interactions since they are CTCF/cohesin-free, yet transcriptionally functional structures9-11. This “moulding step” is followed by a second step, in which the cohesin rings bind to the tips of the “primary TADs” and slide down the loops. This process is very likely due to Scc2/Nipbl, an essential factor not only for loading cohesin, but also for stimulating its translocation12 and its ATPase activity13. This “sliding step” creates self-interactions in the loops and stops at the CTCF binding sites located at the base of the loops that are thus closed and insulated.
Evaluation of the effectiveness of eight screening tools in detecting risk of malnutrition in cirrhotic patients: the KIRRHOS study

Abstract Malnutrition risk screening in cirrhotic patients is crucial, as poor nutritional status negatively affects disease prognosis and survival. Given that a variety of malnutrition screening tools is usually used in routine clinical practice, the effectiveness of eight screening tools in detecting malnutrition risk in cirrhotic patients was sought. A total of 170 patients (57·1 % male, 59·4 (sd 10·5) years, 50·6 % decompensated ones) with cirrhosis of various aetiologies were enrolled. Nutritional screening was performed using the Malnutrition Universal Screening Tool, Nutritional Risk Index, Malnutrition Screening Tool, Nutritional Risk Screening (NRS-2002), Birmingham Nutritional Risk Score, Short Nutritional Assessment Questionnaire, Royal Free Hospital Nutritional Prioritizing Tool (RFH-NPT) and Liver Disease Undernutrition Screening Tool (LDUST). Malnutrition diagnosis was defined using the Subjective Global Assessment (SGA). Data on 1-year survival were available for 145 patients. The prevalence of malnutrition risk varied according to the screening tools used, with a range of 13·5–54·1 %. RFH-NPT and LDUST were the most accurate in detecting malnutrition (AUC = 0·885 and 0·892, respectively) with a high sensitivity (97·4 and 94·9 %, respectively) and fair specificity (73·3 and 58 %, respectively). Malnutrition according to SGA was an independent prognostic factor of within 1-year mortality (relative risk was 2·17 (95 % CI 1·0, 4·7), P = 0·049) after adjustment for sex, age, disease aetiology and Model for End-stage Liver Disease score, whereas nutrition risk according to RFH-NPT, LDUST and NRS-2002 showed no association. RFH-NPT and LDUST were the only screening tools that proved to be accurate in detecting malnutrition in cirrhotic patients.