Miracle-dz/UniFAR-FTUs huggingface dataset:
Aim : To isolate and characterize groundnut-associated bacterial isolates for growth promotion of groundnut in field . Methods and Results : Three

G.K. K ISHORE, S . PANDE AND A.R . PODILE. 2005. Aim: To isolate and characterize groundnut-associated bacterial isolates for growth promotion of groundnut in field. Methods and Results: Three hundred and ninety-three groundnut-associated bacteria, representing the geocarposphere, phylloplane and rhizosphere, and endophytes were applied as seed treatment in greenhouse. Maximum increase in plant biomass (up to 26%) was observed following treatment with a rhizosphere isolate identified as Bacillus firmis GRS 123, and two phylloplane isolates Bacillus megaterium GPS 55 and Pseudomonas aeruginosa GPS 21. There was no correlation between the production of L-tryptophan-derived auxins and growth promotion by the test isolates. Actively growing cells and peat formulations of GRS 123 and GPS 55, and actively growing cells of GPS 21, significantly increased the plant growth and pod yield (up to 19%) in field. Rifampicin-resistant mutants of GRS 123 and GPS 21 colonized the ectoand endorhizospheres of groundnut, respectively, up to 100 days after sowing (DAS), whereas GPS 55 was recovered from both the habitats at 100 DAS. Conclusion: Seed bacterization with phylloplane isolates promoted groundnut growth indicating the possibility of isolating rhizosphere beneficial bacteria from different habitats. Significance and Impact of the Study: Identification of phylloplane bacteria as effective plant growthpromoting rhizobacteria (PGPR) broadens the spectrum of PGPR available for field application.
A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).

The serine/arginine-rich proteins (SR proteins) constitute a family of predominantly nuclear RNA-binding proteins that are present in all metazoan organisms and in plants. The first SR protein was identified nearly 20 years ago as an essential pre-mRNA splicing factor that could also influence alternative splicing in human cell extracts, and was found to have sequence features similar to genetically defined splicing regulators in Drosophila (Ge et al. 1991; Krainer et al. 1991). Specifically, it contained two N-terminal RNP-type RNA-binding domains (RBDs; also known as an RNA recognition motif [RRM]), and a C-terminal region enriched in Arg–Ser dipeptides (RS domain). It was soon realized that a family of SR proteins exists in mammals that are characterized by one or two N-terminal RBDs and a C-terminal RS domain (Fu and Maniatis 1992; Zahler et al. 1992). The SR proteins have since been extensively studied in several species, and found to play important roles in splicing, both as general splicing factors and as regulators of alternative splicing. Unexpectedly, studies during the past decade have extended the role of SR proteins to a diverse set of additional cellular processes, including mRNA nuclear export, mRNA stability and quality control, translation, maintenance of genomic stability, oncogenic transformation, and likely others (Huang and Steitz 2005; Long and Caceres 2009; Zhong et al. 2009). It is thus apparent that SR proteins play multiple important roles in the control of gene expression.
Chemotherapy for metastatic melanoma

Melanoma is a neoplasm with a rising incidence. Early‐stage melanoma is curable, but advanced, metastatic melanoma almost uniformly is fatal, and patients with such advanced disease have a short median survival. Systemic therapy remains unsatisfactory, inducing complete durable responses in a small minority of patients. For the current review, the authors focused on the current role of cytotoxic chemotherapy in the treatment of metastatic melanoma and the future prospects for improvements for multiagent chemotherapy and chemotherapy combined with immunomodulatory and/or molecularly targeted agents. They discuss roles of single‐agent chemotherapy, combination chemotherapy, combinations of chemotherapy with immunomodulatory or hormone agents, biochemotherapy, and combination chemotherapy with targeted therapies. Cancer 2007;109:455–464. © 2007 American Cancer Society.
Roles of volume‐activated Cl− currents and regulatory volume decrease in the cell cycle and proliferation in nasopharyngeal carcinoma cells

Abstract. Objectives: Previously it has been shown, that the volume‐activated plasma membrane chloride channel is associated with regulatory volume decrease (RVD) of cells and may play an important role in control of cell proliferation. We have demonstrated that both expression of the channel and RVD capacity are actively regulated in the cell cycle. In this study, we aimed to further study the role of the volume‐activated chloride current and RVD in cell cycle progression and overall in cell proliferation. Materials and methods: Whole‐cell currents, RVD, cell cycle distribution, cell proliferation and cell viability were measured or detected with the patch‐clamp technique, the cell image analysis technique, flow cytometry, the MTT assay and the trypan blue assay respectively, in nasopharyngeal carcinoma cells (CNE‐2Z cells). Results: The Cl− channel blockers, 5‐nitro‐2‐(3‐phenylpropylamino) benzoic acid (NPPB) and tamoxifen, inhibit the volume‐activated chloride current, RVD and proliferation of CNE‐2Z cells in a dose‐dependent manner. Analysis of relationships between the current, RVD and cell proliferation showed that both the current and RVD were positively correlated with cell proliferation. NPPB (100 µm) and tamoxifen (20 µm) did not significantly induce cell death, but inhibited cell proliferation, implying that the blockers may inhibit cell proliferation by affecting cell cycle progression. This was verified by the observation that tamoxifen (20 µm) and NPPB (100 µm) inhibited cell cycle progress and arrested cells at the G0/G1 phase boundary. Conclusions: Activity of the volume‐activated chloride channel is one of the important factors that regulate the passage of cells through the G1 restriction point and that the Cl− current associated with RVD plays an important role in cell proliferation.
PULMONARY INVOLVEMENT IN RHEUMATOID ARTHRITIS – ANOTHER FACE OF THE COIN

La polyarthrite rhumatoïde (PR) est une maladie auto-immune systémique qui provoque une destruction progressive, symétrique et érosive du cartilage et des os, généralement associée à la production d’anticorps. Il est fréquent que les signes et symptômes articulaires se développent longtemps avant les signes extra-articulaires, mais parfois la maladie pulmonaire peut être la première manifestation de la PR et la caractéristique la plus agressive. Les symptômes respiratoires peuvent précéder les symptômes articulaires dans 10 à 20% des cas. Cependant, ils peuvent être masqués par le mauvais état fonctionnel induit par la maladie articulaire ou l’inflammation chronique. L’atteinte pulmonaire peut être due à l’inflammation chronique causée par la maladie ou peut être secondaire à un médicament immunomodulateur. La maladie pulmonaire elle-même comprend maladies pulmonaires interstitielles, atteinte des voies aériennes (grandes et petites voies respiratoires), atteinte pleurale, nodules pulmonaires ABSTRACT
READING HABITS AMONG CHILDREN IN DISTRICT CENTRAL LIBRARIES IN SOUTHERN TAMIL NADU: A CASE STUDY

The information seeking behaviour of Library users among children was studied based on the objectives of study a questionnaire was set and imparted among randomly selected children respondents. The study was limited to only five districts of Southern Tamil Nadu. The Study areas of five districts were selected based on the bilateral study from earlier research work done. Since, so far, no such study has been conducted on the reading habits among children in Southern districts of Tamil Nadu, the present study has been chosen by the researcher for her research work.
Fosfomycin Resistance in Escherichia coli, Pennsylvania, USA

Fosfomycin resistance in Escherichia coli is rare in the United States. An extended-spectrum β-lactamase–producing E. coli clinical strain identified in Pennsylvania, USA, showed high-level fosfomycin resistance caused by the fosA3 gene. The IncFII plasmid carrying this gene had a structure similar to those found in China, where fosfomycin resistance is commonly described.
The Anderson model on the Bethe lattice: Lifshitz Tails

This paper is devoted to the study of the (discrete) Anderson Hamiltonian on the Bethe lattice, which is an infinite tree with constant vertex degree. The Hamiltonian we study corresponds to the sum of the graph Laplacian and a diagonal operator with non-negative bounded, i.i. d. random coefficients on its diagonal. We study in particular the asymptotic behavior of the integrated density of states near the bottom of the spectrum. More precisely, under a natural condition on the random variables, we prove the conjectured double-exponential Lifschitz tail with exponent 1/2. We study the Laplace transform of the density of states. It is related to the solution of the parabolic Anderson problem on the tree. These estimates are linked to the asymptotic behavior of the ground state energy of the Anderson Hamiltonian restricted to trees of length L. The proofs make use of Tauberian theorems, a discrete Feynman–Kac formula, a discrete IMS localization formula, the spectral theory of the free Laplacian on finite rooted trees, an uncertainty principle for low-energy states, an ǫ-net argument and the standard concentration inequalities.
Gender-Specific Expression of β1 Integrin of VLA-4 in Myelin Basic Protein-Primed T Cells: Implications for Gender Bias in Multiple Sclerosis

Susceptibility to multiple sclerosis is higher in females than males. However, the underlying mechanism behind this gender difference is poorly understood. Because the presence of neuroantigen-primed T cells in the CNS is necessary to initiate the neuroinflammatory cascade of multiple sclerosis, we first investigated how these T cells interacted with astroglia, major resident glial cells of the CNS. Interestingly, we found that myelin basic protein (MBP)-primed T cells from female and castrated male mice, but not from male mice, produced proinflammatory molecules, such as NO, IL-1β, and IL-6 in astroglia, and these responses were purely via contact between T cells and astroglia. Because T cell:glia contact requires several integrin molecules, we examined the involvement of integrins in this process. Both α4 and β1, subunits of VLA-4 integrin, were found to be necessary for T cell contact-induced generation of proinflammatory molecules in astroglia. Interestingly, the expression of β1, but not α4, was absent in male MBP-primed T cells. In contrast, female and castrated male MBP-primed T cells expressed both α4 and β1. Similarly, we also detected β1 in spleen of normal young female, but not male, mice. Furthermore, we show that male sex hormones (testosterone and dihydrotestosterone), but not female sex hormones (estrogen and progesterone), were able to suppress the mRNA expression of β1 in female MBP-primed T cells. These studies suggest that β1, but not α4, integrin of VLA-4 is the sex-specific molecule on T cell surface, and that the presence or absence of β1 determines gender-specific T cell contact-mediated glial activation.
The Influences of Theory of Mind on Negotiation Performance in the Game of Nines by Use of a MetaCognitive Training Agent

This study addresses the concept of theory of mind in terms of negotiation. Using a meta-cognitive training model our research looks at whether training on a negotiation agent that uses theory of mind will improve results in other negotiation tasks, in this case the game of nines. Participants in this study performed game of nines preand post-tests, and then trained with either a meta-cognitive training model with theory of mind or a training model without theory of mind. The difference in scores between preand post-tests for the game of nines were analysed. The results of the experiment are insignificant. This indicates that the presence of theory of mind in a training model does not seem to influence performance in these negotiation tasks.
9. Lexical Semantics

This chapter deals with the lexicon-syntax interface, which is particularly interesting in Korean and currently attracting much attention in cross-linguistic studies. Theories on the lexicon-syntax interface, linking rules in particular, call for a lexicalist hypothesis such that various syntactic aspects of a sentence be determined by the lexical properties of the predicate, just as in Chomsky’s (1981, 1986) Projection Principle. Thus, this chapter aims to characterize the semantic aspects of argument realization patterns – linking rules in Korean. (Jackendoff 1990; Levin and Rappaport Hovav 1995; Pustejovsky 1995; Croft 2012, etc.) Furthermore, this chapter is devoted to identifying the semantic components of alternating predicates in Korean which are relevant to their ability to realize multiple argument structures. The verb classes dealt with in this chapter include psych predicates, verbs of change of location/state, and several verb classes involving causative alternation in Korean.
Scholarly hallucinations and screwed expectations - A new point of view in the IS reference dicipline discussion

Information Systems scholars continuously debate about the nature of the IS discipline. Recently a series of articles have discussed whether the IS field has reached the status of a reference discipline. We address this issue by examining the application of the theory of sensemaking in IS research. Our findings show that the prospects for IS as a reference discipline are not promising. Based on these findings we suggest that IS scholars hallucinate when they a) assume that to become a 'real' academic discipline, IS has to become a reference discipline, and b) believe that IS will become a reference discipline in time. Hence, we describe the IS reference discipline discussion as a misconception, which should be abandoned in the pursuit of a stronger IS discipline.
Trends in the Clinical Characteristics of Patients with Papillary Thyroid Carcinoma in Taiwan

The incidence of thyroid cancer is influenced by many factors including socioeconomic status. As economic conditions have improved in Taiwan, the increased frequency of medical examinations in the general population has led to earlier diagnosis of this indolent malignancy. The purpose of this retrospective study was to compare the clinical characteristics of cases of papillary thyroid cancer diagnosed over a 6-year period from 1993 to 1998 with those patients diagnosed from 1977 to 1992 at a single medical center. Of the 1,485 pathologically verified cases of thyroid cancer from 1977 to 1998, 1,093 had papillary thyroid carcinoma. The mean age of these patients was 40.4 ± 14.6 years. In order to identify trends in the characteristics of patients with thyroid cancer, patients were divided into those diagnosed before and those diagnosed after 1993. Patients diagnosed in these two time periods were also categorized into disease-free or non-disease-free groups depending on their status at the end of 1998. Actuarial survival rates were calculated using the Kaplan-Meier method. Multivariate analysis was performed to assess the independent effect of these variables using the Cox model. By December 1998, 61 (5.6%) of the 1,093 patients with papillary thyroid carcinoma had died. Among them, only 35 (3.2%) patients had died of thyroid cancer. The 5-year Greenwood survival probabilities for the groups diagnosed before and after 1993 were 0.9412 and 0.9817, respectively. The patients diagnosed after 1993 received more aggressive surgical procedures, had smaller tumor size, lower postoperative thyroglobulin levels, less advanced clinical stage at the time of diagnosis, showed more disease-free survival, and a lower mortality rate. In conclusion, the results of this study show that patients with a diagnosis of papillary thyroid cancer after 1993 had a smaller tumor size and a better prognosis than those diagnosed before 1993. This finding emphasizes the importance of early detection in thyroid cancer.
Comparative analysis of codon usage pattern and its influencing factors in Schistosoma japonicum and Ascaris suum

Schistosoma japonicum and Ascaris suum are considered as the major parasites of human which cause various life threatening diseases such as schistomiasis and ascariasis. The codon usage bias (CUB) is known as the phenomenon of more usage of a specific codon than the other synonymous codons for an amino acid. The factors that influence the codon usage bias are mutation pressure, natural selection, gene expression, gene length, GC content, RNA stability, recombination rates, codon position etc. Here we had used various bioinformatic tools and statistical analyses to understand the compositional features, expression level and codon usage bias in the genes of these two species.After estimating the effective number of codon (ENC) in both the species, codon usage bias was found to be low and gene expression was high. The nucleobase A and T were used most often than C and G. From neutrality plot and correspondence analysis it was found that both natural selection and mutation pressure played an important role in shaping the codon usage pattern of both species. Moreover, natural selection played a major role while mutation pressure played a minor role in shaping the codon usage bias in S. japonicum and A.suum. This is the first report on the codon usage biology in S. japonicum and A.suum, and the factors influencing their codon usage bias. These results are expected to be useful for genetic engineering and evolutionary studies.
Developing Affective Model for Measuring and Managing Customer Satisfaction in Container Ports

Nowadays changes in global trade and Maritime transportation always will create competition between ports. Following this competition will be absorption of goods, and it will bring about economic boom. It is therefore appropriate to provide facilities to increase satisfaction of Shipping Lines, which in turn can attract the many shipping lines to port and the port will increase their allegiance. Aimed to identification of factors affecting the extent of satisfaction of container shipping lines from port services as well as prioritization of the factors affecting customer satisfaction in Iraqi container ports, this research has been implemented. Based on the objective, the present research is an applied one as it uses the principles and tactics - formulated in basic researches - for solution of actual and executive problems of Iraqi container ports. Kano model is applied to reach to the objectives of research. Finally, the indicators affecting shipping lines customers? satisfaction were determined and classified according to Kano model. Coefficients of satisfaction and dissatisfaction were estimated and prioritized for each one.
Optimization of multi-stage decision-making process at the game marine environment

The paper describes the process of ship game control in collision situations at sea. For the synthesis process control algorithm uses a simplified model of multi-positional game, allowing determination of the safe and optimal game trajectory of own ship in passing situations with more ships encountered as a sequence of maneuvers, course and speed. Compared three criteria to optimize decision-making process for determining safe trajectory of own ship taking into account the degree of cooperation encountered ships. Considerations exemplified the real situation on the sea registered in the Kattegat Strait.
CERTAIN PROPERTIES OF TRIANGULAR TRANSFORMATIONS OF MEASURES

We study convergence of triangular mappings on Rn, i.e., mappings T such that the ith coordinate function Ti depends only on the variables x1, . , xi. We show that under broad assumptions the inverse mapping to a canonical triangular transformation is canonical triangular as well. An example is constructed showing that convergence in variation of measures is not sufficient for convergence almost everywhere of the associated canonical triangular transformations. Finally, we show that weak convergence of absolutely continuous convex measures to an absolutely continuous measure yields convergence in variation. As a corollary, this implies convergence in measure of the associated canonical triangular transformations.
Dimensions of healthcare safety climate and their correlation with safety outcomes in Japanese hospitals

The present paper reports a study showing a positive contribution of safety climate to safety performance as well as to staff attitudes to error reporting in healthcare. The study comprises 21,666 staff responses (84% mean response rate) from 84 Japanese hospitals to a “safety climate” questionnaire that also included items about respondents’ reporting of their own errors and their interaction with patients who have suffered adverse events. We also obtained incident reports submitted between 2004 and 2006 by nurses from one of the hospitals surveyed. From Spearman’s rho applying to 18 work unit data of the hospital, we identified significant negative correlations between the rate of Level 2+ incidents (suffered at least temporal adverse effects) and several safety climate dimensions, e.g., higher staff motivation, stronger awareness of communication, smaller power distance and larger weight of blame-free atmosphere within an organisation. Similarly, correlation analysis of a sample from 82 hospitals of self-reported staff attitudes showed that small power distance, blame free atmosphere, and some other dimension are tied to openness about an adverse event and staff willingness to perform “positive” reactions to the patient. The content validity is related to how relevant items of a tool or questionnaire are to the targeted construct for the assessment purpose, and this can be judged based on various sources such as relevant theory, empirical literature and expert judgement (Flin et al. 2006). Connecting to this issue, a number of studies have been seeking to develop dimensions of safety climate. For instance, according to reviews of nine instruments measuring safety climate in healthcare (Colla et al. 2005), most of them included the following five dimensions: leadership, policies and procedures, staffing, communication, and reporting. Another literature review (Flin et al. 2006), which included 12 instruments, identified management commitment to safety as the most frequently measured safety climate dimension in healthcare, and suggested that three ‘core’ themes of healthcare safety climate were management/supervisor commitment to safety, safety systems and work pressure— which are related to job demands and workload. In industrial sectors, Flin et al. (2000), which surveyed 18 safety climate tools developed up to late 90’s, extracted common dimensions: management or supervision; risk; work pressure; and competence. The internal reliability of a developed factor is frequently assessed by use of Cronbach’s alpha. As a common acceptance level, 0.7 or higher of the alpha coefficient has been used (Spiliotopoulou 2009).
Mattie Robot - A white-box approach for introducing children with different interests to robotics

“Selective exposure” in educational robotics renders activities playful and keeps children motivated; however, it also influences children’s images of real robots and their expectations of technology development. We designed the Mattie robot as an educational robot for children aged 11 to 13 using everyday materials and easily accessible electronics (white-box approach). Children are introduced to five different areas of robotics based on their interests and actively participate in the integration of these domains to construct a robot. Mattie robot has been employed in a pilot project in seven junior high school classes with over a hundred students. Feedback is very positive: students like it; teachers would appreciate yearly workshops with the robot.