Miracle-dz/UniFAR-FTUs huggingface dataset:
Guidelines on Mobile Device Forensics

Mobile device forensics is the science of recovering digital evidence from a mobile device under forensically sound conditions using accepted methods. Mobile device forensics is an evolving specialty in the field of digital forensics. This guide attempts to bridge the gap by providing an indepth look into mobile devices and explaining technologies involved and their relationship to forensic procedures. This document covers mobile devices with features beyond simple voice communication and text messaging capabilities. This guide also discusses procedures for the validation, preservation, acquisition, examination, analysis, and reporting of digital information.
Analysis of exome-sequenced UK Biobank subjects implicates genes affecting risk of hyperlipidaemia

Rare genetic variants in LDLR, APOB and PCSK9 are known causes of familial hypercholesterolaemia and it is expected that rare variants in other genes will also have effects on hyperlipidaemia risk although such genes remain to be identified. The UK Biobank consists of a sample of 500,000 volunteers and exome sequence data is available for 50,000 of them. 11,490 of these were classified as hyperlipidaemia cases on the basis of having a relevant diagnosis recorded and/or taking lipid-lowering medication while the remaining 38,463 were treated as controls. Variants in each gene were assigned weights according to rarity and predicted impact and overall weighted burden scores were compared between cases and controls, including population principal components as covariates. One biologically plausible gene, HUWE1, produced statistically significant evidence for association after correction for testing 22,028 genes with a signed log10 p value (SLP) of -6.15, suggesting a protective effect of variants in this gene. Other genes with uncorrected p<0.001 are arguably also of interest, including LDLR (SLP=3.67), RBP2 (SLP=3.14), NPFFR1 (SLP=3.02) and ACOT9 (SLP=-3.19). Gene set analysis indicated that rare variants in genes involved in metabolism and energy can influence hyperlipidaemia risk. Overall, the results provide some leads which might be followed up with functional studies and which could be tested in additional data sets as these become available. This research has been conducted using the UK Biobank Resource.
Inhibitory Mechanism of the CXCR4 Antagonist T22 against Human Immunodeficiency Virus Type 1 Infection

ABSTRACT We recently reported that a cationic peptide, T22 ([Tyr5,12, Lys7]-polyphemusin II), specifically inhibits human immunodeficiency virus type 1 (HIV-1) infection mediated by CXCR4 (T. Murakami et al., J. Exp. Med. 186:1389–1393, 1997). Here we demonstrate that T22 effectively inhibits replication of T-tropic HIV-1, including primary isolates, but not of non-T-tropic strains. By using a panel of chimeric viruses between T- and M-tropic HIV-1 strains, viral determinants for T22 susceptibility were mapped to the V3 loop region of gp120. T22 bound to CXCR4 and interfered with stromal-cell-derived factor-1α–CXCR4 interactions in a competitive manner. Blocking of anti-CXCR4 monoclonal antibodies by T22 suggested that the peptide interacts with the N terminus and two of the extracellular loops of CXCR4. Furthermore, the inhibition of cell-cell fusion in cells expressing CXCR4/CXCR2 chimeric receptors suggested that determinants for sensitivity of CXCR4 to T22 include the three extracellular loops of the coreceptor.
Rapid Typing of Borrelia burgdorferi Sensu Lato Species in Specimens from Patients with Different Manifestations of Lyme Borreliosis

To further investigate the pathogenic potential of different Borrelia burgdorferi genospecies, specimens from 27 patients with different manifestations of Lyme borreliosis were analyzed by PCR and reverse line blotting (RLB). In samples from Lyme arthritis patients, B. burgdorferi sensu stricto was predominantly identiﬁed, while in patients with neuroborreliosis or acrodermatitis, Borrelia garinii and Borrelia afzelii , respectively, were exclusively detected. The results demonstrate that PCR-RLB is a valuable tool for epidemiological and pathogenetic studies of Lyme borreliosis.
Ecological requirements of Abies alba in the French Alps derived from dendro‐ecological analysis

Abstract. We used dendro-ecological techniques to investigate fundamental relationships between climate and growth of Abies alba (silver fir) in eastern France. Seven Abies forests in the Trieves region of the French Alps were chosen to represent a wide range of ecological conditions based on the results of previous forest vegetation surveys. In each forest, four trees were sampled in each of five different stands with two cores per tree. These 280 cores were studied using two separate dendro-ecological methods: the pointer years method (based on extreme growth events), and correlation functions between tree ring-widths and monthly climatic data. Data from 11 meteorological stations were combined to provide a regional analysis of precipitation and minimum and maximum temperatures. The two dendro-ecological methods appear to be complementary, as the first technique emphasizes common and low intensity linear correlations between ring-widths and climatic variations, and the second method emphasizes extreme and unusual climatic events such as exceptionally cold or dry years. Across all sites, drought in the previous year was consistently correlated with a low growth rate; however, other climatic variables varied substantially among sites. For example, drought in the current year reduced growth more in the low elevation sites than in the high elevation sites and severe winter frost reduced growth the most in the high altitude sites and the driest site. Moreover, certain growth responses are better correlated with the age of the stands, the canopy closure and the floristic composition of the community than the abiotic factors, emphasizing the value of dendro-ecological sampling based on phytosociological units.
Food distribution, dominance, and aggressive behaviors in bonnet macaques

Resource availability or distribution may affect interindividual competition in species such as primates, which forage in social groups, and several field studies suggest that dominance status predicts access to restricted food sources. Increased competition due to restricted resources may result in the intensification of aggressive behaviors. The study reported here examines the impact of manipulation of the distribution of food resources in a laboratory‐housed group of bonnet macaques to assess the impact of distribution on aggressive behaviors. Food was restricted to a space which allowed access to only one or two individuals at a time or was dispersed throughout the living enclosure to allow universal access in alternating periods. During periods of clumped distribution, the monkeys obtained access to the food in order of their dominance status in the group. In addition, overall levels of aggressive behaviors increased, submissive behavior increased, and play decreased during periods of clumped distribution of food. These results confirm the findings from field studies indicating increases in agonism with restriction of food resources. These findings also have implications for primate colony management, in terms of developing strategies for minimizing intragroup aggression in captive groups.
Identification of a Porphyromonas gingivalis Receptor for the Streptococcus gordonii SspB Protein

Colonization of the plaque bioﬁlm by the oral pathogen Porphyromonas gingivalis is favored by the presence of antecedent organisms such as Streptococcus gordonii . Coadhesion between P. gingivalis and S. gordonii can be mediated by the SspB protein of S. gordonii ; however, the P. gingivalis cognate receptor for this protein has not been identiﬁed. In this study, we identiﬁed a surface protein of P. gingivalis that interacts with the SspB protein. Coprecipitation between P. gingivalis outer membrane proteins and puriﬁed SspB protein demonstrated that a 100-kDa P. gingivalis protein bound to SspB. The 100-kDa protein also bound to an engineered strain of Enterococcus faecalis that expresses the SspB protein on the cell surface. Monospeciﬁc polyclonal antibodies to the 100-kDa protein inhibited the binding between P. gingivalis and S. gordonii in a dose-dependent manner up to 86%. Amino acid sequencing of the 100-kDa protein showed homology to a protein previously identiﬁed as the P. gingivalis minor ﬁmbria. The minor ﬁmbrial protein may exist as a complex with a hemagglutinin-like protein since the genes encoding these proteins are adjacent on the chromosome and are cotranscribed. Thus, the P. gingivalis receptor for
Effects of Green Tea extract on color and Lipid oxidation in Ground Beef Meat

The effects of green tea extract on relative concentration of myoglobin (Mb), metmyoglobin (MetMb) and oxymyoglobin (MbO2) forms and on peroxide values formation in ground beef meat was studied. Green tea extract(GTE) was mixed with ground meat (0.0, 0.5, 1.0, 1.5 and 2.0%) of meat weight. Samples stored for 1, 4, 8 and 12 days at 4 Co. There were significant differences (P<0.05) between control samples and samples treated with different levels of green tea extract in terms of myoglobin forms and peroxide values after storage under refrigeration. Treated samples with GTE developed low peroxide values compared with control and enhanced the proportion of each myoglobin form present. However, addition of 1 – 2 % of GTE to ground beef meat was adequate in reduced meat lipid oxidation and stabilized the meat color through decreased metmyoglobin (MetMb) formation after refrigeration
A STUDY OF CHLOROPHYLLIN OF MEDICINAL PLANTS, ITS CHEMICAL CHARACTERIZATION AND ANTI–PROLIFERATIVE ACTIVITY WITH SPECIAL REFERENCE TO SOLANUM TRILOBATUM L. ON LIVER CELL LINE

Objective: Plants are the richest source of bioactive compounds and they have been used as medicine also. Chlorophyllin (CHL) is water-soluble derivative of chlorophyll (chl) in which magnesium has been replaced with copper and the phytol chains lost. Chlorophyllin has been used by human population for over 50 y for medicinal purposes with no adverse effects. Chlorophyllin is a promising chemo preventive agent to block cancer primarily by inhibiting carcinogen such as AFB 1. The objective was to extract the bioactive pigment chlorophyllin from medicinal plants and to study its anticarcinogenic property on liver cell lines. Methods: In the present study the bioactive pigment, chlorophyllin was extracted and estimated from six medicinal plant leaves and characterized by IR and NMR. Further, based on the high chlorophyllin content (12.21µg/ml), Solanum trilobatum L. was selected for the study of anticarcinogenic property against two types of cell lines: HepG2 cell lines (Human Hepatocellular Carcinoma) and Vero cell lines (African Green Monkey kidney). Results: It was found that the inhibitory effect of chlorophyllin was found on cancer cell lines (IC 50 value at 48H was 62.5μg/ml) and absent on Vero cell lines. Standard chlorophyllin was used as control for all the studies. Conclusion: This is the first report on the effect of natural chlorophyllin from the leaves of Solanum trilobatum L. on HepG2 cell lines. The in vitro data suggests that the consumption of the leaves of Solanum trilobatum L. or as chlorophyllin may impart anticancer effects.
Stability of fruit bases and chocolate fillings

Xaropes com alto conteudo de acucar e frutas desidratadas podem ser adicionados a recheios de produtos de chocolate a fim de reduzir a necessidade da adicao de aromas e corantes, atribuindo um apelo natural ao produto. Foram produzidas bases de frutas e recheios com morango e maracuja liofilizados e casca de laranja in natura. Testes reologicos de oscilacao foram usados para determinar a estabilidade do produto e tendencia de vida de prateleira. Valores de G´ G´´ durante 90 dias de armazenamento. Observou-se que valores de tensao de cisalhamento nao variaram significantemente, sugerindo a estabilidade dos produtos durante o periodo estudado. Para todos os recheios, foi obtido comportamento semelhante ao das bases, indicando que estas estabelecem grande influencia no comportamento e estabilidade dos recheios. O uso da matriz de acucar colaborou com um prolongamento da vida de prateleira da base de fruta, que conseguiu manter o produto final armazenado em temperatura ambiente por periodo acima de um ano. A boa estabilidade e condicoes de armazenamento permitem o uso das bases de frutas em producoes artesanais e industriais.
A targeted selective treatment approach for effective and sustainable sheep worm management: investigations in Western Australia

The effectiveness of a targeted selective treatment (TST) approach to the management of sheep worms in adult Merino ewes was compared with a normal worm control program on three properties in south-western Western Australia. For a TST strategy, a proportion of a flock is left undrenched when flock treatments are administered. This establishes a population of worms in refugia, isolated from the effects of anthelmintics, which dilutes the population of worms that survive drenching and, hence, minimises the development of anthelmintic resistance. The main worm genera present in this trial were Teladorsagia and Trichostrongylus. For the TST approach, an initial flock worm egg count was used to determine the proportion of the flock to be drenched at any time, and treatments were then given to that proportion of the flock, with treated individuals identified as those in the poorest body condition. Over a period of 10–12 months, the TST groups on the three properties received 60%, 53% and 73% of the number of drenches administered to the normal treatment groups, in which all sheep were drenched. No clinical signs of parasitism or adverse effects on reproductive indices occurred in the TST groups. Although bodyweight gain and wool weight were ~2 kg and 0.3 kg, respectively, lower in two of the TST groups than in the normal treatment groups, the differences were not significant, and body condition scores of the TST groups were consistently greater than optimal production recommendations. The TST concept has potential as an easily implemented approach to sustainable drench management and would reduce the cost and labour associated with worm control. However, further studies are required to develop decision indices for various environments to ensure a balance between worm control efficiency and sheep production.
Improving radiograph analysis throughput through transfer learning and object detection

Pacific Northwest National Laboratory, Richland, WA, USA; Washington State University, Richland, WA, USA; SIGN Fracture Care International, Richland, WA, USA Contributions: (I) Conception and design: J Brandi-Lozano, C Sivaraman, LG Zirkle; (II) Administrative support: C Sivaraman; (III) Provision of study materials or patients: J Short, ID Lewis, BD Barnes, LG Zirkle; (IV) Collection and assembly of data: JA Bilbrey, EF Ramirez; (V) Data analysis and interpretation: JA Bilbrey, EF Ramirez; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Chitra Sivaraman. Pacific Northwest National Laboratory, 902 Battelle Boulevard, P.O. Box 999, Richland, WA, USA. Email: chitra.sivaraman@pnnl.gov.
Microbial Quality and Direct PCR Identification of Lactic Acid Bacteria and Nonpathogenic Staphylococci from Artisanal Low-Acid Sausages

ABSTRACT Detection of six species of lactic acid bacteria and six species of gram-positive catalase-positive cocci from low-acid fermented sausages (fuets and chorizos) was assessed by species-specific PCR. Without enrichment, Lactobacillus sakei and Lactobacillus curvatus were detected in 11.8% of the samples, and Lactobacillus plantarum and Staphylococcus xylosus were detected in 17.6%. Enriched samples allowed the detection of L. sakei and S. xylosus in all of the samples (100%) and of Enterococcus faecium in 11.8% of the sausages. The percentages of L. curvatus, L. plantarum, Staphylococcus carnosus, and Staphylococcus epidermidis varied depending on the sausage type. L. curvatus was detected in 80% of fuets and in 57% of chorizos. L. plantarum was found in 50% of fuets and 100% of chorizos. S. epidermidis was detected in only 11.8% of fuets, and S. carnosus was detected in only 5.9% of chorizos. Lactococcus lactis, Staphylococcus warneri, and Staphylococcus simulans were not detected in any sausage type. From a microbiological point of view, 70.6% of the samples could be considered of high quality, as they had low counts of Enterobacteriaceae and did not contain any of the food-borne pathogens assayed.
Scope for Designing High Torque Switched Reluctance Motor with Low Ripples

The paper discusses the problem of the ripples in the torque characteristic of the switched reluctance motor which is the main drawback otherwise the SRM possess excellent characteristics for applications in many commercial drives. Lots of researches attempted to solve the problem by changing the design parameters of this type of motors but the average torque decreases. There is limitation on the output torque of the SRM per unit volume; to decrease the ripples the average torque always decreases. From this point of view the paper clarifies the necessity of optimising the SRM for at least two cost functions: low ripples and high average torque. The optimization of the SRM is difficult and inaccurate due to high nonlinear characteristic of the SRM; so the paper introduces a direct and simple way to select the parameters of the SRM for these two cost functions. In addition, the paper shows how to adjust the operating parameters to run the SRM to deliver high output torque with low ripples.
MODELLING AND PARAMETRICAL APPROXIMATION OF AN ELECTRIC ARC FURNACE OF STEELMAKING

Electrical arc is a stochastic process; witch is the principal cause of power quality problems, including voltages dips, harmonic distortion, unbalance loads and flicker. So it is difficult to make an appropriate model for an EAF. The factors that effect EAF operation are the melting or refining materials, melting stage, electrode position (arc length), electrode arm control and short circuit power of the feeder. So arc voltages, current and power are defined as a nonlinear function of the arc length. In this article we propose our own empirical function of the EAF and model for the mean stages of the melting process. This study is important, because improvement of Electric Arc means high productivity (in tons/year) and lowest possible costs arising form energy consumption, electrode and refractory wear.
White Matter Measures and Cognition in Schizophrenia

White matter (WM) abnormalities are commonly reported in schizophrenia but whether these arise from the axon or myelin compartments or both is not known. In addition, the relationship between WM abnormalities and cognitive function is not fully explored in this condition. We recruited 39 individuals with schizophrenia spectrum disorders and 37 healthy comparison subjects. All participants underwent MRI scanning at 4 Tesla to collect data in the prefrontal white matter on magnetization transfer ratio (MTR) and diffusion tensor spectroscopy (DTS) which provide information on myelin and axon compartments, respectively. We also collected Matrics Composite Cognitive Battery (MCCB) and Stroop cognitive data. We found an elevated N-acetylaspartate (NAA) apparent diffusion coefficient in schizophrenia in this cohort as in our previous work; we also observed poorer performance on both the MCCB composite and the Stroop in schizophrenia patients compared to controls. The MTR measure was correlated with the MCCB composite (r = 0.363, p = 0.032) and Stroop scores (r = 0.387, p = 0.029) in healthy individuals but not in schizophrenia. Since this is the first exploration of the relationship between these WM and cognitive measures, we consider our analyses exploratory and did not adjust for multiple comparisons; the findings are not statistically significant if adjusted for multiple comparisons. These findings indicate that WM integrity is associated with cognitive function in healthy individuals but this relationship breaks down in patients with schizophrenia.
Effects of Regulatory Focus and Emotions on Information Preferences: The Affect-as-Information Perspective

This study explored the effects of regulatory focus and emotions on information preferences, specifically information selection preferences (experiment 1) and implicit information preferences (experiment 2). Our findings revealed that, in the promotion-focused condition, individuals preferred hedonic information (vs. functional information) when they were happy (vs. sad). However, emotions’ effects on information preferences were attenuated in the prevention-focused condition. In experiment 3, we tested whether regulatory focus and salient emotions influenced information preferences. The results suggested that regulatory focus and salient emotions had no significant interactive effect on information selection preferences, but had a significant interactive effect on implicit preferences. These results further our understanding of the psychological dynamic mechanism involved in information preferences, which augments the affect-as-information theory.
First Phantom-Based Quantitative Assessment of Scandium-44 Using a Commercial PET Device

Scandium (Sc) is a promising candidate for theranostic applications due to the existence of radioisotopes suitable for both imaging and therapy. A “proof-of-concept” study regarding first-in-human use of 44Sc for imaging metastatic neuroendocrine tumors was reported recently, however, quantitative assessment of 44Sc-based PET images was not performed. The aim of this study was to evaluate quantitative capabilities of 44Sc-PET using a commercial PET scanner. The NEMA/IEC body phantom with 44Sc was acquired according to the local protocol used for whole-body oncological [18F]FDG PET examinations. Additionally, we characterized the signal recovery (recovery coefficient—RC) according to the iteration number. For all reconstructions, pertinent image corrections (normalization, dead time, activity decay, random coincidence, and attenuation) were applied. Presently, 44Sc scatter corrections are not optimized and could, thus, result in quantitative bias. To investigate the best option, the data were reconstructed using different available scatter corrections (relative -RelSC- and absolute -AbsSC-) and an additional prompt-gamma correction (PGC). System cross-calibration with the local dose calibrator (BGcal) and image noise, expressed by the coefficient of variation (COV), were evaluated in the homogeneous background region (5 kBq/mL) of the phantom. Maximum (RCmax) and 50% threshold recovery coefficients, corrected for background (RCA50), were measured for all spherical inserts (25 kBq/mL) of the phantom. Acceptable COV (<15%) was achievable with low iteration numbers (<3). BGcal differences were low: mean BGcal were 77.8, 81.3, and 86.7%, for RelSC, AbsSC, and PGC, respectively. RC values exceeded the present RC range recommended for [18F]FDG procedures. Using the iterations to be evaluated, RCA50 ranged from 29.9 to 59.9% for the smallest lesion (spherical insert of 10 mm diameter) and from 45.5 to 80.3% (13 mm), 66.4 to 75.6% (17 mm), 71.7 to 75.7% (22 mm), 75.1 to 78.6% (28 mm), and 76.7 to 80.9% (37 mm) for the, respectively spherical inserts. The results of this study show that clinical 44Sc-PET imaging has the potential to provide signal recovery in lesions of different sizes comparable to current 18F-PET standards. In order to improve the quantitative accuracy of 44Sc PET, optimized corrections are still necessary and will be investigated further in future.
Penetration of Clindamycin, Cefoxitin, and Metronidazole into Pelvic Peritoneal Fluid of Women Undergoing Diagnostic Laparoscopy

A single dose of clindamycin, cefoxitin, or metronidazole was administered to each of 30 women. The mean concentration of cefoxitin in pelvic fluid at 1 h exceeded those of the other two drugs (P < 0.007). Cefoxitin concentrations were inferior to those of the other drugs when compared with the published MIC for 90% of Bacteroides fragilis strains.