Miracle-dz/UniFAR-FTUs huggingface dataset:
Cholesterol awareness and treatment in patients with coronary artery disease participating in cardiac rehabilitation.

OBJECTIVES To survey cholesterol management practices among patients with coronary artery disease enrolled and not enrolled in cardiac rehabilitation. BACKGROUND The National Cholesterol Education Program (NCEP) initially established guidelines regarding cholesterol awareness and treatment in 1987. Serum cholesterol reduction is most effective for reducing cardiac events in patients with established coronary artery disease, yet surveys of cholesterol awareness and treatment have not included these patients. METHODS Three hundred seventy-nine men and women with coronary artery disease were surveyed according to cholesterol awareness, serum cholesterol level, frequency of lipid-lowering medication use, and frequency of achievement of a serum total cholesterol < 5.2 mmol/L (200 mg/dL) corresponding the 1987 NCEP guidelines for coronary artery disease patients, which were in place at the time of the study survey. RESULTS Overall, 72% of the patients were aware of their cholesterol level, with an average serum total cholesterol of 5 5 +/- 1.0 mmol/L (213 +/- 39 mg/dL). Use of lipid-lowering medication was 26%. Forty-three percent had a total cholesterol < 5.2 mmol/L (200 mg/dL). Patients enrolled in a long-term cardiac rehabilitation program demonstrated enhanced cholesterol awareness (78%), lower total cholesterol values (5.2 +/- 0.9 mmol/L [203 +/- 36 mg/dL]), higher use of lipid-lowering the therapy (34%), and more frequent achievement of total serum cholesterol of < 5.2 mmol/L (200 mg/dL) (48%) compared to the other patient groups (all P < .05). CONCLUSIONS Patients with coronary artery disease demonstrate relatively low rates of cholesterol awareness, lipid-lowering medication use, and achievement of total serum cholesterol < 5.2 mmol/L (200 mg/dL) corresponding to the 1987 NCEP guidelines. Participation in long-term cardiac rehabilitation is associated with enhancement of these rates. Further efforts to educate physicians and develop programs to optimize cholesterol management in patients with coronary artery disease are needed.
BRain health and healthy AgeINg in retired rugby union players, the BRAIN Study: study protocol for an observational study in the UK

Introduction Relatively little is known about the long-term health of former elite rugby players, or former sportspeople more generally. As well as the potential benefits of being former elite sportspersons, there may be potential health risks from exposures occurring during an individual’s playing career, as well as following retirement. Each contact sport has vastly different playing dynamics, therefore exposing its players to different types of potential traumas. Current evidence suggests that these are not necessarily comparable in terms of pathophysiology, and their potential long-term adverse effects might also differ. There is currently limited but increasing evidence that poorer age-related and neurological health exists among former professional sportsmen exposed to repetitive concussions; however the evidence is limited on rugby union players, specifically. Methods and analysis We present the protocol for a cross-sectional study to assess the association between self-reported history of concussion during a playing career, and subsequent measures of healthy ageing and neurological and cognitive impairment. We are recruiting a sample of approximately 200 retired rugby players (former Oxford and Cambridge University rugby players and members of the England Rugby International Club) aged 50 years or more, and collecting a number of general and neurological health-related outcome measures though validated assessments. Biomarkers of neurodegeneration (neurofilaments and tau) will be also be measured. Although the study is focusing on rugby union players specifically, the general study design and the methods for assessing neurological health are likely to be relevant to other studies of former elite sportspersons. Ethics and dissemination The study has been approved by the Ethical Committee of London School of Hygiene and Tropical Medicine (reference: 11634-2). It is intended that results of this study will be published in peer-reviewed medical journals, communicated to participants, the general public and all relevant stakeholders.
Botulinum Toxin Type A Targets RhoB to Inhibit Lysophosphatidic Acid-Stimulated Actin Reorganization and Acetylcholine Release in PC12 Cells: A Possible Mechanism For Intervention

Abstract : We showed that the G-protein activator lysophosphatidic acid (LPA) triggered actin reorganization followed by ACh release in nerve growth factor treated PC12 cells, and that BoNT/A blocked both events through degradation of RhoB by the proteasome. Overexpression of wild-type RhoB caused to overcome toxin s inhibitory effect on actin reorganization/exocytosis stimulated by LPA. A knockdown of the RhoB gene via targeted siRNA transfection resulted in total inhibition of both actin reorganization and ACh release induced by LPA. We conclude that the RhoB signaling pathway regulates ACh release via actin cytoskeletal reorganization, and that botulinum toxin inhibits neuroexocytosis by targeting RhoB pathway.
Summarization Evaluation for Text and Ani Nenkov

This paper surveys current text and speech summarization evaluation approaches. It discusses advantages and disadvantages of these, with the goal of identifying summarization techniques most suitable to speech summarization. Precision/recall schemes, as well as summary accuracy measures which incorporate weightings based on multiple human decisions, are suggested as particularly suitable in evaluating speech summaries.
Heat Transfer and Turbulent Fluid Flow over Vertical Double Forward-Facing Step

Abstract — Numerical study of heat transfer and fluid flow over vertical double forward facing step were presented. The k-w model with finite volume method was employed to solve continuity, momentum, and energy equations. Different step heights were adopted for range of Reynolds number varied from 10000 to 40000, and range of temperature varied from 310K to 340 K. The straight side of duct is insulated while the side of double forward facing step is heated. The result shows augmentation of heat transfer due to the recirculation region created after and before steps. Effect of step length and Reynolds number observed on increase of local Nusselt number particularly at recirculation regions. Contour of streamline velocity is plotted to show recirculation regions after and before steps. Numerical simulation in this paper done by used ANSYS FLUENT 14. Keywords — Turbulent flow, Double forward, Heat transfer, Separation flow.I. I NTRODUCTION HE crises of energy in global has been encourage researchers to look for new techniques which improve of thermal performance. One of common method to increase efficiency of energy system equipment is by change the design geometry of channel. The fluid flow over forward or backward-facing step found in many practical applications such as heat exchangers, chemical process, turbine blades, and power plants. There are many experimental and numerical study of effect separation flow at forward or backward-facing step on increase of enhancement heat transfer rate. Heat transfer to fluid flow over single and double forward-facing step experimentally studied by Shakouchi and Kajino [1] with using laser Doppler anemometer where the results appeared that the reattachment region by a new heat flux probe, and Oyakawa et al. [2], [3] used jet discharge. Saldana and Anand [4] performed numerical study of laminar fluid flow over a horizontal forward-facing step in three dimensions. They showed that the increase of Reynolds number leads to increase of reattachment length and average Nusselt number.
Family Perceptions of the Usual Source of Care among Children with Asthma by Race/Ethnicity, Language, and Family Income

A usual source of care (USC) can serve as the foundation for good primary health care and is critical for children living with a chronic health condition. This study applies national data to the following objectives: (1) describe family reports of the presence and characteristics of the USC for children with asthma; (2) examine evidence of systematic differences in the USC for these children with asthma by race/ethnicity, English language proficiency in Hispanic respondents, and family income; and (3) conduct multivariate analysis adjusting for possible confounding factors to examine independent effects of race/ethnicity, language, and income. Data from the 1996–2000 Medical Expenditure Panel Survey (MEPS) were analyzed. Overall, 95% of children with asthma had a USC, with Spanish-speaking Hispanics least likely to report a USC (89%). There were significant differences in USC attributes by race/ethnicity, language, and income, with the largest differences by type of provider and accessibility. Hispanics with poor English language proficiency had the greatest accessibility barriers.
3D InISAR-based target reconstruction algorithm by using a Multi-Channel ground-based radar demonstrator

A 3D reconstruction algorithm for non cooperative moving targets is proposed in this paper. This method exploits interferometric ISAR imaging (InISAR) to estimate the heights of the dominant scatterers with respect t o the Image Projection Plane. In particular, the interferometric phases measured from two orthogonal baselines are used to reconstruct t he third dimension from 2D-ISAR images. Some aspects that make such approach effective in a real scenario have been faced and their problems solved. In order to verify the effectiveness and the reliability of this technique, data from a suitably designed Multi-Channel ground-based radar has been used.
Integrating Handicapped and Nonhandicapped Preschoolers: Developmental Impact on Nonhandicapped Children

To examine the effects of placing young nonhandicapped children in classes primarily containing handicapped children, 16 nonhandicapped children were randomly assigned to four integrated special education preschool classes. A control group consisting of 16 children, matched for age and sex, who were enrolled in three preschool classes containing only nonhandicapped children, was employed as a comparison. A battery of assessments were administered to both groups at the beginning and end of the academic year. No significant differences in performance on these measures were found. Placement of nonhandicapped children in integrated special education classes, where the majority of peers were handicapped, did not appear to interfere with normal development.
Improving Voting Systems’ User-Friendliness, Reliability, & Security

About half of Americans have limited confidence that their vote will be properly counted. These fears have focused attention on voting system reliability, security, and usability. Over the last decade, substantial research on voting systems has demonstrated that many systems are less usable and secure than they should be. Producing truly reliable voting systems demands more than just following the federal guidelines enacted in 2005 (which, although well intentioned, have failed to substantially improve current systems) or simply updating voting systems to electronic voting computers using monies allocated by the 2002 Help America Vote Act (HAVA). In fact, HAVA has inadvertently led to the purchase of systems that may have actually increased the vote error rate. Key reforms needed to deliver reliable voting systems include substantial testing for usability especially regarding the accurate capture of voter intent and the reduction of voter error rates, and measures to ensure the integrity of elections, such as election officials’ ability to secure ballots.
A Pedigree Partitioning Approach to Quantitative Trait Loci Mapping of IgE Serum Level in the GAW12 Hutterite Data

We present a semi‐automatic method that uses principles from factor analysis to subdivide large pedigrees into smaller, non‐overlapping sub‐pedigrees. Application of our method to the Genetic Analysis Workshop 12 Hutterite pedigree yielded 12 sub‐pedigrees that were used to carry out a genome‐wide linkage scan for IgE serum level in SOLAR. Two‐point analyses resulted in strong evidence for linkage to two marker loci on chromosome 1, D1S3723 (lod = 3.70) and D1S534 (lod = 3.58). Multipoint analysis resulted in a maximum lod of 4.58 on chromosome 1 at 143 cM. After extending the two pedigrees that contributed the most evidence for linkage, the maximum lod score decreased to 4.18, with most of the evidence for linkage due to a single large sub‐pedigree. © 2001 Wiley‐Liss, Inc.
Applying Particle Swarm Optimization and Differential Evolution Combined with Finite Element Method to Optimize Cable

Particle swarm optimization (PSO) and differential evolution (DE) algorithm are biologically inspired computing, which simulate the behavior of survival of the fittest from the systems of nature biology, ecology and so on. As heuristic random algorithms, they have characteristics of self-adaptation, self-organization, self- learning, etc. PSO and DE can be used to solve various complex problems that are difficult by using traditional calculation methods. Based on the platform of ANSYS finite element soft, parametric programming of a single-phase cable and a three-phase cable is accomplished in the paper by using ANSYS parameter design language (APDL). Optimization calculation of the maximum electric field strength of cable insulation layer is realized by PSO and DE combined with finite element method (FEM). That biologically inspired computing combined with FEM provides reference and enlightenment for optimizing high- voltage equipment in aspects of electromagnetic field.
Distinguishing Cause and Effect : Inferring causal direction in two variables

The task of attributing cause and effect is prevalent and pervasive in history as well as present everyday lives. The factors affecting economy, human health, global warming can help us in solving many problems. The standard way to detect causal direction is to perform random experiments, which can be expensive, unethical or even impossible to perform. Inferring the same from already collected data can solve many problems. In this project we dealt with finding causal direction among two variables, given their distribution. This problem was part of the Cause Effect pair challenge. We used functional noise model and deterministic relational models to find the cost involved in causal directions for the two variables . We determined the existence of a relation using a SVM classifier on features extracted from the distribution of data.
SENTIMENT ANALYSIS AND CLASSIFICATION USING LEXICON-BASED APPROACH AND ADDRESSING POLARITY SHIFT PROBLEM

As we know that in recent years e-commerce has been growing, so volume of online reviews on the web is also increasing for different sides due to which we can understand that the particular product or things are good for use or not and their current status in market. In Natural Language Processing (NLP) and text mining, different models and methods are useful for text representation and categorization purposes. BagOf-Word (BOW) model is one such model used to model the text. But polarity shift problem is a major factor in Bag-Of-Word model which can effect on classification performance of Sentiment Analysis. In our methodology, we address the polarity shift problem by detecting, removing and modifying negation from extracted review to identify where the sentiment orientation is actually changing in given review. Our main idea is Sentiment analysis and classification which is based on machine learning approach using Lexicon based antonym dictionary. We build system for Sentence-level sentiment classification. We first extract product reviews from one of the customized shopping portal. When extracted reviews are simple sentences then system is trained to directly find its opinion target, and classify it according to its sentiment polarities i.e. is positive, negative and neutral class labels. When extracted reviews are compound and complex sentences then we first split it into subsentences and build a model based on some rules to detect, remove and modify polarity shift in contrast of negation to identify where the sentiment orientation is changing in compound or complex sentences. After that, we classify review according to its polarity and determine the targets of opinion given in review. Furthermore, we extend our system for opinion summarization based on opinion features or aspects and graphically represent overall summary of Positive, Negative and Neutral sentiments of customer for each product.
Pressure and stress analysis for an underwater vehicle

Underwater vehicles are widely used in both military and civilian operations for more than 60 years. They are the best tools to perform dull, dangerous and dirty tasks in the water. So the distribution principles of static pressure and stress along the vehicle hull must be found out when designing hull shape and choosing the materials. The static pressure and stress on an underwater hull is simulated in this paper by using CFD commercial software ANSYS Fluent. The obtained principles are useful for future research.
Performance evaluation of server virtualization in data center applications

One of the important targets in new generation data centers is minimizing the cost through efficient use of available resources. Virtualization is a new technology that provides an opportunity for extension of independent virtual resources based on available physical systems. This paper evaluates performance of virtualized versus non-virtualized servers in data center applications. We have presented a tile based evaluation based on heterogeneous workloads to compare several key parameters and demonstrate effectiveness of virtualization techniques. Moreover, we have evaluated the virtualized server models using V-Motion techniques and maximum sever consolidation. Results of evaluation for different criteria confirm that server virtualization technique has high throughput and CPU usage as well as good performance with noticeable agility. Experimental results which are obtained through our prototype model demonstrate that server virtualization can significantly reduces resource consumption while improves system performance. Obtained results certify that server virtualization can be a strategic decision for saving the investment, increasing service performance and creating new virtual environments.
How Today's College Students use Wikipedia for Course-related Research

Findings are reported from student focus groups and a large-scale survey about how and why students (enrolled at six different U.S. colleges) use Wikipedia during the course-related research process. A majority of respondents frequently used Wikipedia for background information, but less often than they used other common resources, such as course readings and Google. Architecture, engineering, and science majors were more likely to use Wikipedia for course-related research than respondents in other majors. The findings suggest Wikipedia is used in combination with other information resources. Wikipedia meets the needs of college students because it offers a mixture of coverage, currency, convenience, and comprehensibility in a world where credibility is less of a given or an expectation from today’s students.
On Wide Area Protection

When a major power system disturbance strikes the power network, protection and are required to stop the power system degradation, restore the system to a normal state, and minimize the impact of the disturbance. In some cases, the present control actions are not designed for a fast-developing disturbance and may be too slow. The paper discusses special protection schemes and new technologies for advanced, wide area protection.
The heart in hypertension.

HYPERTENSIVE heart disease can be defined as the response of the heart to the afterload imposed on the left ventricle by the progressively increasing arterial pressure and total peripheral resistance produced by hypertensive vascular disease. Although the response sometimes appears to be out of proportion to the level of the arterial pressure, it is primarily the result of the hemodynamic overload. Hypertension can cause or is related to various cardiac manifestations, among them left ventricular hypertrophy, congestive heart failure, cardiac dysrhythmias, and ischemic heart disease. Although the risk of atherosclerotic coronary heart disease is related to the systolic and diastolic .
Effectiveness of Cryptosporidium spp . oocysts detection and enumeration methods in water and milk samples

Cryptosporidium spp. oocyst recovery in water and milk samples was evaluated. Samples were inoculated with a suspension of 1.2×10 Cryptosporidium spp. oocysts and submitted to centrifugal flotation, using different solutions (sucrose, NaCl, MgSO4, ZnSO4, AlSO4, NH4SO4 40% and NH4SO4 80%). Centrifugation of the samples was carried out in two stages for concentration using two methods that differed in the order in which the saturated solutions were used, namely only in the first stage of method I and only in the second stage of method II. Oocyst identification was performed using the Kinyoun and Koster histochemical staining techniques. Samples analyzed by method I showed different degree of oocyst recovery, namely 10.9% with NaCl and 42.5% with MgSO4 in water and milk samples, while those samples analyzed by method II showed 10.6% with NaCl and 5.3% with sucrose in water and milk, respectively. Histochemical staining methods have no influence on the degree of oocysts recovery. The efficiency of Cryptosporidium spp. oocysts recovery methods depends on the nature and composition of the sample and on the methodology used for oocyst concentration.
Shaping the future: Towards the next generation of powerful, pervasive, and service-oriented distributed systems

The recent significant progresses in (wired and wireless) network and middleware technologies have opened a huge opportunity for many new research areas and paradigms related to open distributed computing systems. This paper aims to define a synthesis among these areas that are in one way or another related either to multi-agent systems or Grid computing or both, such as Semantic Grid, Agent-based Grid Computing, Service-oriented Architectures, (and utility-based computing). It is argued that there is a substantial overlap between the key issues being addressed by these areas. Thus, it makes sense to stimulate interdisciplinary research at a higher level of synthesis. This will open an exciting opportunity for ambient and open distributed computing environments that combines the qualities of the above mentioned individual research areas.
enhancers and promoters Drosophila Genome-wide phosphoacetylation of histone H 3 at Material Supplemental

Material Supplemental http://genome.cshlp. org/content/suppl/2012/04/11/gr.136929. 111.DC1. html References http://genome.cshlp. org/content/22/6/1081.full. html#ref-list-1 This article cites 31 articles, 12 of which can be accessed free at: License Commons Creative . http://creativecommons.org/licenses/by-nc/3.0/ described at as a Creative Commons License (Attribution-NonCommercial 3.0 Unported License), ). After six months, it is available under http://genome.cshlp. org/site/misc/terms.xhtml for the first six months after the full-issue publication date (see This article is distributed exclusively by Cold Spring Harbor Laboratory Press