Miracle-dz/UniFAR-FTUs huggingface dataset:
Abnormal Change in Body Weight and Non-Fasting Blood Glucose Levels of Mouse Strain C57BL/6J in Generating Type 2 Diabetes Model

The commercially available inbred obesity-prone C57BL/6J (B6) and outbred stock ICR mice (3-week old) purchased from a breeder of Beijing were weaned onto high-fat diet (HFD), HFD-3% fructose water (HFDF) and standard rodent chow, respectively. After exposure to the diets for six weeks, HFD and HFDF fed mice were injected intraperitoneally with streptozotocin (STZ, 100 mg/kg body weight) and kept on the same diet for next four weeks. Body weight was recorded weekly. Non-fasting blood glucose levels of HFD and HFDF fed mice were measured before and after STZ injections. The body weight of HFD-fed and HFDF-fed B6 mice were significantly lower than that of the control, but body weight of HFD-fed and HFDF-fed ICR mice were significantly higher than that of the control. After injection of STZ, blood glucose levels were above the stardardized criterion (11 mmol/L) for the diabetes mouse model in both HFD and HFDF fed ICR mice, but reverse in B6 mice. The type 2 diabetes model was generated successfully in ICR but not in B6 mice, regardless of whether fructose was supplied. The current results indicated that ICR mouse is still a useful and economical strain for HFD–induced/STZ-treated type 2 diabetes model, and that some variation may occur in the genetic composition among B6 mice bred by different breeders.
Identification of Streptomyces sp. Producing Antibiotics Against Phytopathogenic Fungi, and Its Structure

In order to develop a biocontrol agent that can effectively control Fusarium wilt on Cymbidium genus, the effectiveness of antagonistic microbes against the cause pathogen was screened. The selected microbe showed a broad spectrum of antifungal activity, and the culture broth of this microbe had better preventive effect on Fusarium wilt than the commercial chemical agent in the pot assay. This isolated strain, GBA-12, was identified as Streptomyces kasugaensis, and the antifungal substance was purified from a broth culture of GBA-12. This purified substance was identified as a polyene macrolide (YS-822A) that was newly discovered from Streptomyces kasugaensis, and it exhibited antifungal activity against several phytopathogenic fungi.
Diversity of foaming producing nocardioform actinomycetes from wastewater treatment plants in Spain

In this study we have isolated nocardioform actinomycetes from wastewater treatment plants (WWTPs) with foaming problems and were identified by phenotypic and genotypic procedures. Chemotaxonomic test and analysis of 16S rRNA gene sequences showed that the isolated belonged to the genera Corynebacterium, Dietzia, Gordonia, Millisia, Mycobacterium, Nocardia, Rhodococcus, Segniliparus, Skermania, Turicella, Tsukamurella and Williamsia. The nucleotide sequences similarity values among the isolated strains and type strains were between 98,52% and 100%. The importance of this work is double; first, to understand the complexity of the foaming forming populations and second, the fact that WWTPs can be a good source of microorganisms with many potential applications, such as bioremediation, and biodegradation.
ELECTROPHORETIC INVESTIGATION OF THE FAMILY SCORPAENIDAE

Thirty-one species of three genera of the family Scorpaenidae were separated into 17 groups based on starch gel electrophoretic comparison of muscle proteins and six enzy­ matic systems. This study concluded that relatively greater similarity existed between the Pacific Sebastes and the Atlantic Sebastes than between either and the other genera. Ten of the 27 species of Pacific Sebastes tested had unique biochemical profiles which may be useful for identification of specimens. 'I'he family Scorpaenidae contains several ge­ nera in the Pacific and Atlantic Oceans. On the Pacific coast of North America there are four genera-Sebastes,' Sebastolobus, Scorpaena, and Scorpaenodes. The genus of Pacific Sebastes contains over 50 species (Tsuyuki et al., 1968). In this genus new species and ex­ tensions of known distribution ranges have been described in recent years (Westrheim, 1965; Westrheim and Tsuyuki, 1967; Nishimoto, 1970; 'I'suyuki and Westrheim, 1970). At present there are difficulties in showing taxonomic re­ ~ations and, in some instances, in making positive ldentification of specimens using morphometric and meristic methods, although taxonomic re­ lations can be obtained by biochemical methods. ~tarch gel electrophoresis-developed by Smith­ les (1955)-coupled with histochemical proce­ dUres (Hunter and Markert, 1957) is one of the best biochemical techniques for taxonomic stUdies. Scorpaenid muscle proteins and hemoglobin Were investigated by starch gel electrophoresis by Tsuyuki et al. (1968). They suggested that the electrophoretic evidence did not support the separation of the two genera Sebastodes and Sebastes. Chu (1968), using disk electrophore­ sis of muscle proteins, found different patterns
Nasopharyngeal SARS-CoV2 viral loads in young children do not differ significantly from those in older children and adults

The role of children in the spread of the SARS-CoV2 coronavirus has become a matter of urgent debate as societies in the US and abroad consider how to safely reopen schools. Small studies have suggested higher viral loads in young children. Here we present a multicenter investigation on over five thousand SARS-CoV-2 cases confirmed by real-time reverse transcription (RT) PCR assay. Notably, we found no discernable difference in amount of viral nucleic acid among young children and adults.
Decentralized Langevin Dynamics

Langevin MCMC gradient optimization is a class of increasingly popular methods for estimating a posterior distribution. This paper addresses the algorithm as applied in a decentralized setting, wherein data is distributed across a network of agents which act to cooperatively solve the problem using peer-to-peer gossip communication. We show, theoretically, results in 1) the time-complexity to $\epsilon$-consensus for the continuous time stochastic differential equation, 2) convergence rate in $L^2$ norm to consensus for the discrete implementation as defined by the Euler-Maruyama discretization and 3) convergence rate in the Wasserstein metric to the optimal stationary distribution for the discretized dynamics.
Phonon-limited electron mobility in Si, GaAs, and GaP with exact treatment of dynamical quadrupoles

We describe a new approach to compute the electron-phonon self-energy and carrier mobilities in semiconductors. Our implementation does not require a localized basis set to interpolate the electron-phonon matrix elements, with the advantage that computations can be easily automated. Scattering potentials are interpolated on dense $\mathbf{q}$ meshes using Fourier transforms and ab initio models to describe the long-range potentials generated by dipoles and quadrupoles. To reduce significantly the computational cost, we take advantage of crystal symmetries and employ the linear tetrahedron method and double-grid integration schemes, in conjunction with filtering techniques in the Brillouin zone. We report results for the electron mobility in Si, GaAs, and GaP obtained with this new methodology.
Engineering a Culturable Serratia symbiotica Strain for Aphid Paratransgenesis

Insects have remarkably diverse and integral roles in global ecosystems. Many harbor symbiotic bacteria, but very few of these bacteria have been genetically engineered. ABSTRACT Aphids are global agricultural pests and important models for bacterial symbiosis. To date, none of the native symbionts of aphids have been genetically manipulated, which limits our understanding of how they interact with their hosts. Serratia symbiotica CWBI-2.3T is a culturable, gut-associated bacterium isolated from the black bean aphid. Closely related Serratia symbiotica strains are facultative aphid endosymbionts that are vertically transmitted from mother to offspring during embryogenesis. We demonstrate that CWBI-2.3T can be genetically engineered using a variety of techniques, plasmids, and gene expression parts. Then, we use fluorescent protein expression to track the dynamics with which CWBI-2.3T colonizes the guts of multiple aphid species, and we measure how this bacterium affects aphid fitness. Finally, we show that we can induce heterologous gene expression from engineered CWBI-2.3T in living aphids. These results inform the development of CWBI-2.3T for aphid paratransgenesis, which could be used to study aphid biology and to enable future agricultural technologies. IMPORTANCE Insects have remarkably diverse and integral roles in global ecosystems. Many harbor symbiotic bacteria, but very few of these bacteria have been genetically engineered. Aphids are major agricultural pests and an important model system for the study of symbiosis. This work describes methods for engineering a culturable aphid symbiont, Serratia symbiotica CWBI-2.3T. These approaches and genetic tools could be used in the future to implement new paradigms for the biological study and control of aphids.
Basic mechanism of airway epithelial repair : role of IL-13 and EGFR glycosylation

Epithelial regeneration following injury is crucial for restoring epithelial function to its normal state. Epidermal Growth Factor Receptor (EGFR) has an essential role in maintenance and repair of epithelial tissues. Glycosylated structures attached to many glycoproteins including EGFR can modulate protein function. The main goals of my doctoral research project have been to investigate: (1) the basic mechanism of airway epithelial repair, focusing on the EGFR and IL13 pathways and (2) the role of Sialyl Lewis x (sLe’) and sLex decoration of EGFR in airway epithelial repair. In chapter II, we showed that injured Airway Epithelial Cells (AEC) release EGFR ligands (EGF and HB EGF) and IL13 during repair. Moreover, for the first time, we demonstrated that IL13 plays an important role in epithelial repair, and that its effect is mediated through release of HB-EGF and activation of EGFR. We found that the reparative effects of IL-13 on AEC are mediated via IL-l3Ra2. This receptor was thought to act only as a decoy receptor until recently. In chapter III, we demonstrated an important role for a specific fucose-containing carbohydrate structure, sLex, in bronchial epithelial repair. In chapter IV we showed that sLe’ decorates EGFR on Primary Normal Human Bronchial Epithelial (NHBE) cells and that EGFR decoration with sLe’ increases after mechanical injury. Fucosyltransferase IV (FucT-IV) showed to mediate sLe’ synthesis in AEC and demonstrated a temporal expression during epithelial repair. Using small interfering RNA (siRNA) and blocking antibody for sLe’ we found that sLex has an important role in modulating EGFR activity during epithelial repair.
Cell proliferation and nestin expression in cortex and SEZ of MCAO rats

AIM: To explore the effect of brain ischemia injury on cell proliferation and nestin expression in cortex and subependymal zone (SEZ). METHODS: Using a local brain ischemia model(MCAO), BrdU positive cells of cortex and subependymal zone (SEZ), also nestin positive cells, were observed by immunohistochemistry. RESULTS: BrdU and nestin positive cells in SEZ of MCAO rats were obviously increased. In cortex, only nestin positive cells were observed. CONCLUSION: Neural stem cells in SEZ and cortex were activated after brain ischemia, it may be related with neural recovery after brain ischemia injury.
Thread-modular Counter Abstraction for Parameterized Program Safety

Automated safety proofs of parameterized software are hard: State-of-the-art methods rely on intricate abstractions and complicated proof techniques that often impede automation. We replace this heavy machinery with a clean abstraction framework built from a novel combination of counter abstraction, thread-modular reasoning, and predicate abstraction. Our fully automated method proves parameterized safety for a wide range of classically challenging examples in a straight-forward manner.
Outfit Selection Recommendation System using Classification Techniques

: Recommendation of outfit helps the people in taking the right decision while purchasing and also increases the sales. The analysis of the accuracy of the classified dataset using various data mining techniques and algorithms is the key concept of this paper. The accuracy when the algorithms are applied on the balanced dataset, imbalanced dataset, dataset with attribute reduction and without attribute reduction is compared. To perform the attribute reduction, we are using cfsSubsetEval, consistencySubsetEval and chisquaredAttributeEval. The algorithms that are used to classify the dataset are Random Forest, Naive Bayes, zeroR, Multilayer Perception, RBF Network and AdaboostM1. The main challenge is thatthe virtual dataset is imbalanced through which we got poor results with less accuracies. This dataset is balanced using SMOTE analysis to obtain higher accuracies and also attribute reduction is performed to compare the accuracies obtained. In comparison with the existing method, the maximum accuracy rate produced by the Poonkuzhali Sugumaran and Vinodh
Bioinformatic Analysis of Rice DA1 Gene

Using the methods of comparative genomics and bioinformation,a homolog of the Arabidopsis DA1 gene controlling seed and organ size was identified in rice genome,and named OsDA1.Also the exon-intron structure,protein domains,cis-elements and evolution of the gene was analyzed.The results indicated that the putative protein encoded by OsDA1 was characterized with a LIM domain and Zinc-finger domain,two ubiquitin interaction motifs.This suggeted that OsDA1 might have the similar function to AtDA1 and play important roles in regulating seed and organ size.This investigation also found that there were multiple cis-elements which could response to different hormones and stress signals existed in the promoter region of OsDA1 and were some different from those of AtDA1.These results suggested that OsDA1 gene might be different from AtDA1 on expression regulation,and it involved in not only development of seed and other organs,but also plant hormone signalings and stress responses.This research laid a foundation for functional dissection of OsDA1 gene in rice development and stress response,also its relationship with heterosis.
IS JURASSIC SCHMEISSNERIA AN ANGIOSPERM

The discovery of Schmeissneria sinensis in western Liaoning marks an important record in the study on history of angiosperms. Schmeissneria is a fossil plant genus with an almost 170-year-long history. Recently reported Schmeissneria sinensis demonstrates some new characters previously unrecognized (a longitudinal complete septum and a closed tip in the central unit of the premature female structures). These new characters prompt us to review the affinity of Schmeissneria. Based on a careful examination of the definition of angiosperms and characters of Schmeissneria, Wang et al. concluded that Schmeissneria represents a new taxon with angiospermy. According to the current definition of angiosperms, Schmeissneria may be put in angiosperms. This will push the record of angiosperms back to the earliest Jurassic. However, the possibility of Schmeissneria being a new seed plant group parallel to angiosperms, in case the definition of angiosperms were altered, cannot be excluded completely for the time being. Here we briefly introduce the history of Schmeissneria, its characters and how Wang et al. determined it as an angiosperm.
Multifunctional Graphene Composites for Electromagnetic Shielding and Thermal Management at Elevated Temperatures

A method for scalable synthesis of epoxy composites with graphene and few‐layer graphene fillers is described, and the electromagnetic interference (EMI) shielding and thermal properties of such composites at elevated temperatures are reported. The tested materials reveal excellent total EMI shielding of SET ≈ 65 dB (≈ 105 dB) at a thickness of 1 mm (≈ 2 mm) in the X‐band frequency range. At higher filler loading fractions, composites reveal a room‐temperature cross‐plane thermal conductivity of 11.2 ± 0.9 Wm−1 K−1, which is a factor of ×41 larger than that of the pristine epoxy. Interestingly, the EMI shielding efficiency improves further as the temperature increases while the thermal conductivity remains approximately constant. The enhancement in the EMI shielding is explained by the temperature dependence of the two electrical conduction mechanisms, electronic band‐type conduction inside the fillers, and hopping conduction between the fillers. The excellent EMI shielding and heat conduction characteristics of such multifunctional graphene composites at high temperatures are promising for packaging applications of microwave components where EMI shielding and thermal management are important design considerations.
Isolated Intramedullary Relapse of Lung Cancer: About A Case

Case Report Intramedullary metastases (IMM) are rare. Lung cancer is the most common primary. We report in this work the case of a 59-year-old patient, previously treated with chemo-radiotherapy for locally advanced lung cancer, who presented with an isolated intramedullary relapse. Palliative radiotherapy and systemic corticosteroids were initiated with an improvement of neurological symptoms. The patient died 3 months after the diagnosis of IMM. Through this work, we underline the singularity of the isolated character of the reported relapse and the importance of an early diagnosis of these lesions, often associated with a poor prognosis.
Wpływ fotoperiodu na biologię ziemniaka

Cykl życiowy wielu roślin powiązany jest z porami roku, których zmiana sygnalizowana jest przez zmieniającą się długość dnia. Roślinne fotoreceptory, reagujące na światło foto¬morfogenetycznie aktywne lub jego brak, umożliwiają roślinom odbiór sygnału o zmieniających się warunkach. Długość fotoperiodu jest istotnym czynnikiem regulującym procesy rozwojowe również w przypadku ziemniaka. W przeglądzie podsumowano wiedzę z dotychczasowych badań nad wpływem fotoperiodu na biologię rodzaju Solanum. Począwszy od udomowiania ziemniaka w odmiennych od miejsca pochodzenia szerokościach geograficznych, omówiono wpływ długości dnia na kwitnienie, tuberyzację oraz odporność na Phytophthora infestans, organizm powodujący najważniejszą pod względem ekonomicznym chorobę ziemniaka. Wybrane procesy życiowe stanowią najistotniejsze elementy biologii ziemniaka, ponieważ dotyczą jego zdolności do przetrwania i dalszego rozmnażania w zróżnicowanym środowisku.
Forward Forecast of Stock Price Using Sliding-window Metaheuristic-optimized Machine Learning

: — Stock market trading is an activity in which investors need fast and accurate information to make effective decisions. Since many stocks are traded on a stock exchange, numerous factors influence the decision-making process. Moreover, the behaviour of stock prices is uncertain and hard to predict. For these reasons, stock price prediction is an important process and a challenging one. This leads to the research of finding the most effective prediction model that generates the most accurate prediction with the lowest error percentage. This paper reviews studies on machine learning techniques and algorithm employed to improve the accuracy of stock price prediction. The neural network, one of the intelligent data mining technique that has been used by researchers in various areas for the past 10 years. Prediction and analysis of stock market data have got an important role in today’s economy. The various algorithms used for forecasting can be categorized into linear (AR, MA, ARIMA, ARMA) and non-linear models (ARCH, GARCH, Neural Network). In this paper, we are using four types of deep learning architectures i.e. Multilayer Perceptron (MLP), Recurrent Neural Networks (RNN), Long Short-Term Memory (LSTM) for predicting the stock price of a company based on the historical prices available. Here we are using day-wise closing price of two different stock markets, National Stock Exchange (NSE) of India and New York Stock Exchange (NYSE). The network was trained with the stock price of a single company from NSE and predicted for five different companies from both NSE and NYSE. It has been observed that CNN is outperforming the other models. The network was able to predict for NYSE even though it was trained with NSE data. This was possible because both the stock markets share some common inner dynamics. The results obtained were compared with ARIMA model and it has been observed that the neural networks are outperforming the existing linear model (ARIMA).
Place-Based Redistribution

Governments around the world redistribute to distressed areas by conditioning taxes and transfers on location. We show that when poor households are spatially concentrated, transfers from one location to another can yield equity gains that outweigh their efficiency costs, even when income-based transfers are set optimally. Expressions for the optimal transfer size depend on the mobility of households, the earnings responses of movers, and sorting patterns. Surveys find support for targeting tax credits to poor Americans who live in distressed places. A calibration exercise finds optimal transfers of the same order of magnitude as prominent American zone policies. Institutional subscribers to the NBER working paper series, and residents of developing countries may download this paper without additional charge at www.nber. org.
Accumulation of Brominated Flame Retardants in Harbour and Dall’s Porpoises from Hokkaido

In the present study, stranded or by-caught harbour porpoises (Phocoena phocoena) and Dall’s porpoises (Phocoenoides dalli) were collected from Hokkaido, Japan, and brominated flame retardants (PBDEs and HBCDs) and Polychlorinated biphenyls (PCBs) concentrations in their blubber were measured. All the target compounds were detected in all the specimens. Levels of PCBs were significantly higher than those of PBDEs and HBCDs. PCBs, PBDEs and HBCDs levels in harbour porpoises of the present study were lower than those in Dall’s porpoises (p = 0.03). This result might reflect the difference in habitat and feeding behavior between these species. Additionally, HBCDs levels in harbor porpoises and Dall’s porpoises analyzed in this study were higher than finless porpoises from Seto Inland Sea, suggesting contamination by HBCDs is more serious in Hokkaido. To evaluate the temporal trends, blubber samples of adult male harbour porpoises and Dall’s porpoises collected in 1985–2009 and 1980–2008 were analyzed. Concentrations of PCBs in both species did not show any trend during 1980–2009. In contrast, remarkable increasing trend of HBCDs in harbour porpoise was observed. PBDEs and HBCDs concentrations in Dall’s porpoises also increased during the survey period. These results suggest growing consumption of these chemicals in Japan and surrounding countries in recent years.