Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of items recommendations methods for heritage sites

When visiting a heritage site for the first time, the visitor can be overtaken by the amount of available contents, such as paintings, artworks, etc. Some heritage sites possess very large collections with various items. Historic sites possess very large collections and their main purpose is to make these available and attractive to the public. Nevertheless, visitors cannot access all objects and collections present in the site, as they will be lacking time to visit everything, or according to their profile and preferences. This is why, it’s important to customize visits through targeted recommendations. This paper addresses the recommendation of items through a critical analysis of works and projects that have dealt with this type of problems. Then an hybrid architecture is proposed which takes into account the context aspect.
Quel rôle aujourd'hui pour l'infection à Helicobacter pylori dans la maladie ulcéreuse gastro-duodénale ?

Helicobacter pylori (H. pylori) et les traitements par anti-inflammatoires non steroidiens (AINS) ou aspirine restent aujourd'hui les deux grandes causes des ulceres duodenaux (UD) et gastriques (UG). Neanmoins, dans certains pays ou regions dans lesquels la prevalence de l'infection a baisse de facon importante, et probablement egalement dans lesquels la consommation d'AINS/aspirine est importante, la proportion d'ulceres non associes a H. pylori est elevee. La proportion d'ulceres lies ni a H. pylori ni aux AINS reste neanmoins faible, inferieure a 6 % dans la majorite des etudes. Ce chiffre est par ailleurs peut-etre surestime, car la recherche d'H. pylori et surtout celle de la prise d'aspirine ou d'AINS n'ont pas toujours ete faites de facon optimale. Il n'y a pas eu suffisamment d'etudes permettant d'evaluer les caracteristiques des UG consideres idiopathiques (apres elimination d'un cancer). Dans deux etudes, les UD non lies a H. pylori ou aux AINS etaient associes dans deux tiers a trois quarts des cas a des maladies generales souvent severes (cirrhose, insuffisance respiratoire, renale, cardiaque, cancer). De nombreuses maladies digestives peuvent donner un ulcere duodenal, la maladie de Crohn est probablement la plus frequente. Une hypersecretion gastrique acide, comme chez les UD infectes par H. pylori, semble etre le facteur pathogenique de l'UD idiopathique avec, en plus, une augmentation de la charge acide duodenale. Le devenir des ulceres idiopathiques a ete peu etudie. Il n'y a pas d'informations fiables concernant le risque de complications. Une eventuelle augmentation du risque de resistance aux antisecretoires n'est pas demontree et le traitement repose sur les inhibiteurs de la pompe a protons a la dose permettant la cicatrisation.
DECOMPOSITION OF CHANGES TO DISEASE AND DISABILITY LIFE EXPECTANCY IN ENGLAND

Any morbidity life expectancy (or life expectancy withdiseases not necessarily limiting) is influenced by a rangeof conditions whose effect is unknown unlessdecomposition or cause-elimination techniques areapplied to determine their individual contributions incomparable units (e.g. years). Identifying the mainconditions which trigger the greatest numbers of yearsspent with morbidity would help to assess and targetareas where the most intervention is needed. Adecomposition method which enables the identificationof the main causes influencing disability life expectancyis available. Up to now, the method has only beenapplied to obtain the effects attributable to each maindisease separately. This was the approach applied toDutch data by Nussleder and Looman (2004). The focus on single diseases, as opposed to co-morbidity,can hide, however, significant information in an ageingpopulation such as that in the UK; at older ages peoplemight suffer, in fact, from multiple disease conditions(Cornoni-Huntley
Performance of Concurrency Control Mechanisms in Centralized Database Systems

Deparment of Computer Science, KMG College of Arts and Science,R.S. Road, Gudiytham,Tamilnadu 632 602, India revsoft86@gmail.com Abstract The objective of this study is to propose user control system that definitely increases the performance of realtime data service. However the most existing work on this RTDB was based on very critical closed loop control system. To overcome this problem we design a system called user control database model which stimulate the overload transaction during run time. We also design quality of service scheme and it allows to setting requirements for QOS transaction. The performance of proposed algorithm evaluated in different experiments. So the proposed system will definitely satisfies our needs even critical conditions like overload or run-time errors.
Modélisation des barrières non tarifaires et leur impact sur les échanges internationaux : une application aux pays méditerranéens

La doctrine du libre-echange a favorise la creation d’un cadre multilateral en 1947 avec l’accord general sur les tarifs douaniers et le commerce (GATT) puis avec l’Organisation Mondiale du Commerce (OMC) en 1995. Les negociations commerciales multilaterales sous l’egide du GATT puis de l’OMC, aboutissent a une reduction considerable des droits de douane au niveau mondial. Or, devant la diminution progressive des droits de douane, un fort accroissement des barrieres dites non tarifaires (BNT) apparait.En effet, l’expansion du commerce international et l’extension des regles commerciales multilaterales a de nouveaux domaines, autrefois proteges, tels que l’agriculture, les services et la propriete intellectuelle ont amene beaucoup de pays a faire un usage plus intensif, voire « abusif » des barrieres non tarifaires, une issue pour contourner la regle « libre-echangiste ». Ces barrieres non tarifaires viennent ainsi completer, voire remplacer les droits de douane et peuvent reduire, voire annuler la valeur des consolidations tarifaires. De plus, les BNT sont deux fois plus restrictives que les droits de douane, CNUCED, (2005) et elles limitent nettement plus l’acces aux marches que les droits tarifaires, CNUCED, (2012). Egalement, les BNT peuvent prendre differentes formes, elles n’ont pas le meme degre de restrictivite et ne s’appliquent pas de la meme methode. Elles varient en fonction des pays et des produits et correspondent a differents objectifs.La presente these s’inscrit dans le cadre des travaux de quantification des barrieres non tarifaires et vise l’evaluation du degre de restrictivite des BNT tarifaires appliquees sur les importations des pays sud-mediterraneens (MED) en provenance des pays de l’Union Europeenne (UE) dans le cadre de l’integration euro-mediterraneenne. Ce travail de recherche introduit deux modeles econometriques : le premier modele est une equation d’ « importations », il evalue l’ampleur des barrieres non tarifaires appliquees sur les importations (corrigees des tarifs) des pays MED en provenance du partenaire UE et ceci a travers le calcul des equivalents tarifaires ad-valorem. Le second modele est une equation gravitationnelle, il estime le role des BNT et les couts de commerce dans les echanges UE-MED pour aboutir a une analyse plus fine de l’impact des BNT et d’autres barrieres a l’echange a savoir : les droits de douane ; les couts de transport ; la performance logistique ; les facteurs de la proximite culturelle et les facteurs institutionnels sur le commerce euro-mediterraneen.
The effect of target speech distance on reaction time under multi-talker environment

This study aims to investigate whether distance cues affect reaction time (RT) in a target sound search task. To do this, we investigated the effects of three cues, respectively, when the sound object was close to the listener. The cues considered in this study were the perceived source intensity as well as two binaural cues, interaural level differences (ILD) and auditory parallax. In the psychoacoustic experiments, a target and a distracter, both speech sounds, were spatialized using head-related transfer functions (HRTF). In the first experiment, a target and a distracter were presented to the listener from the same distance, and this distance was varied. Second, the position of the distracting speech sound was fixed at a far distance and that of the target speech soundwas moved closer to the listener. The results of the first experiment suggest that the sound intensity constantly influences to shorten RT. The results of the second experiment suggest that the main contributor to faster RT is the target to distracter ratio at both ears,and that spatial unmasking using binaural cues also shows a positive effect.
Development of Novel Imaging and Image Modeling Techniques for the Assessment andQuantification of Inter-Vertebral Motion Using MRI

MAHATO, NILADRI KUMAR, Ph.D., August 2016, Biological Sciences Development of Imaging and Image Modeling Techniques for the Assessment and Quantification of Inter-Vertebral Motion Using MRI Director of Dissertation: Brian C. Clark Low back pain (LBP) is the leading cause of disability worldwide with more than eight hundred billion dollars of direct and indirect costs associated with LBP being incurred annually in the US alone. About 80-90% of all LBP patients do not have a definitive diagnosis of the etiology of pain, and are grouped under the non-specific LBP cohort. A group of such patients with unspecified etiology for their back pain are believed to have their LBP due to un-controlled and often, more than normal segmental motion involving one or more of their lumbar vertebrae. As such, many surgical treatments for LBP are directed at reducing inter-vertebral motion at and around an affected segment. The most common approaches for quantifying vertebral motion are based on radiographic assessments, which in many cases preclude scientific inquiry (e.g., use of high radiation equipment is not permitted for scientific investigations in some states, and, even when permitted, presents a major roadblock for serial assessments). This project was undertaken to develop and examine the feasibility, reliability and accuracy of a technique that used magnetic resonance (MR) images, custom built 3-D models and animations of spine-segment motion to quantify displacements in a calibrated imaging space. Experiment 1 explored the feasibility of developing an MRI-based spine kinematics quantification technique that involved (i) creating MRI compatible solid-body objects, (ii) scanning axial images of the objects in the MRI machine to create static 3-D virtual models of the solid-bodies, (iii) scanning the solid bodies as they were displaced
Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer

AIM To uncover the roles of tumor-promoting gene ZEB1 in aerobic glycolysis regulation and shed light on the underlying molecular mechanism. METHODS Endogenous zinc finger E-box binding homeobox-1 (ZEB1) was silenced using a lentivirus-mediated method, and the impact of ZEB1 and methyl-CpG binding domain protein 1 (MBD1) on aerobic glycolysis was measured using seahorse cellular flux analyzers, reactive oxygen species quantification, and mitochondrial membrane potential measurement. The interaction between ZEB1 and MBD1 was assessed by co-immunoprecipitation and immunofluorescence assays. The impact of ZEB1 and MBD1 interaction on sirtuin 3 (SIRT3) expression was confirmed by quantitative polymerase chain reaction, western blotting, and dual-luciferase and chromatin-immunoprecipitation assays. RESULTS ZEB1 was a positive regulator of aerobic glycolysis in pancreatic cancer. ZEB1 transcriptionally silenced expression of SIRT3, a mitochondrial-localized tumor suppressor, through interaction with MBD1. CONCLUSION ZEB1 silenced SIRT3 expression via interaction with MBD1 to promote aerobic glycolysis in pancreatic cancer.
Using a Flexible Online Tutorial to Individualize Learning Activities

Abstract —Teaching highly abstract topics like system modeling demands sophisticated teaching methods. They should enable different learning paths and take into account different learning styles. FOTO is a flexible online tutorial introducing basics of object oriented modeling. Its didactic concept defines three levels of representation supporting highly individualized learning. electronic teaching, didactics, flexible online tutorial 1. I NTRODUCTION The constructivist learning theory explains learning as a highly individual process. It is central that knowledge as a process and product is constructed individually and must be embedded in an active process [1]. Therefore, classes should offer a variety of learning activities and should provide alternative learning paths. Electronic teaching is one possibility to facilitate individual learning activities in classes. Flexible online tutorials allow students to individualize their learning activities. They are learner-centered, placing interaction between the learner and the system in the foreground [2]. At Fachhochschule Zentralschweiz we developed a flexible online tutorial introducing basics of object oriented modeling (FOTO) [3] that is specifically suited to individualize learning activities. In section 2 the didactic concept of the tutorial is introduced. Section 3 describes the three learning levels providing learning content. In section 4 the different aspects of individualization are presented. Central requirements concerning learning content as well as the learning management system are discussed in section 5.
Is Tesamorelin a Safe and Effective Drug to Treat Lipodystrophy in HIV Patients

Objective: The objective of this selective EBM review is to determine whether or not Tesamorelin is a safe and effective drug to treat lipodystrophy in HIV patients. Study Design: Review of three English language primary randomized controlled trials published between 2005-2010. Data Sources: Randomized, placebo-controlled, double-blind clinical trials comparing Tesamorelin to a visually matched placebo were found using PubMed. Outcome(s) Measured: Each of the three clinical trials assessed the improvement of lipodystrophy (accumulation of visceral adipose tissue) in HIV patients. In addition, they noted how the improvement in lipodystrophy would impact patient's self body image and quality of life. Prior to the study, all patients received a CT scan in order to get a visceral adipose tissue baseline, this allowed researchers to note patient's percent change from baseline. Furthermore, patients also completed a self-perceived body image questionnaire. Patients rated their “belly size” comparing their current appearance to their perceived healthy look with scores from -100 (much thinner) to +100 (much bigger). Similarly, they rated their “belly image distress” from 0 (extremely upsetting and distressing) to 100 (extremely encouraging); and “belly profile” by choosing from six silhouettes scored from 0 (normal) to 5 (very dysmorphic). Results: Three randomized-controlled trials were included in this review. Results from each study reveals that Tesamorelin (2 mg) is a safe and effective drug to treat lipodystrophy in HIV patients. Similarly, patient's self body image and quality of life also improved due to the reduction in their visceral adipose tissue. Although all three trials reported similar adverse events, for two of the trials, headache was the most common; while injection site erythema was the most common for the other trial. Conclusion: The three randomized-controlled trials have proven that Tesamorelin is a safe and effective treatment for lipodystrophy in HIV patients. It is because of these clinical trials that Tesamorelin was approved by the FDA on November 10, 2010 and it is currently the only alternative treatment for lipodystrophy in HIV patients besides surgery or diet and exercise.
Psychosexual problems of infertile women in India.

: Female partners of 200 infertile couples have been interviewed for psychosexual problems. There were 105 women who complained of one sexual problem or more. Decreased frequency of intercourse and anorgasmia in wife were the most common problems identified. A significant number of husbands considered the testing of semen along with scheduled coitus to be a problem. These problems appear to be related to the feeling of being infertile rather than any social or personal factors, such as age, education, or income. The majority of the women welcomed this in-depth interview for sexual problems.
Study between Foundations of Analysis and English Performance Test: A Case of Solomon Mahlangu College of Science and Education

The purpose of this study was to determine the association between English screening test and the Foundations of Analysis (MTH 100) course examination results among first-year students majoring in Informatics and Infomathematics degree programs as well as to determine the ratio of males and females enrolment for the past three years. Screening tests and MTH 100 examination results from 2015/16, 2016/17 and 2017/18 Informatics and Infomathematics students from Department of Mathematics, Informatics and Computing Science were used and analyzed using the chi-square test at a = 0.05. The results of the study showed that the ratio of male and female students enrolled in Informatics and Infomathematics degree program for the past three years is low, below 1:6 and no clear association existed in performance between the Screening test and MTH 100. Findings are expected to provide the beneficial source of information to several education stakeholders as to why the gap between males and females has not been reduced to a reasonable level as well as to why there is more failure in screening tests compared to MTH 100
Local path planning during locomotion over irregular terrain

Aftab E. Patla, Ewa Niechwiej, Luiz Santos Gait and Posture Lab, Department of Kinesiology, University of Waterloo, Waterloo, Ontario N2L3G1 Abstract We have been exploring the factors that guide the selection of alternate foot placement during locomotion in a cluttered environment. The results show that when normal landing area is unavailable or undesirable, individuals select an alternate foot placement that minimizes changes to the normal gait trajectory and ensures dynamic stability. These experiments shed light on fundamental issue of local path planning and are relevant to the design of legged robots designed to function in an unstructured environment.
Integrating Voice Quality Cues in the Pitch Perception of Speech and Non-speech Utterances

Pitch perception plays a crucial role in speech processing. Since F0 is highly ambiguous and variable in the speech signal, effective pitch-range perception is important in perceiving the intended linguistic pitch targets. This study argues that the effectiveness of pitch-range perception can be achieved by taking advantage of other signal-internal information that co-varies with F0, such as voice quality cues. This study provides direct perceptual evidence that voice quality cues as an indicator of pitch ranges can effectively affect the pitch-height perception. A series of forced-choice pitch classification experiments with four spectral conditions were conducted to investigate the degree to which manipulating spectral slope affects pitch-height perception. Both non-speech and speech stimuli were investigated. The results suggest that the pitch classification function is significantly shifted under different spectral conditions. Listeners are likely to perceive a higher pitch when the spectrum has higher high-frequency energy (i.e., tenser phonation). The direction of the shift is consistent with the correlation between voice quality and pitch range. Moreover, cue integration is affected by the speech mode, where listeners are more sensitive to relative difference within an utterance when hearing speech stimuli. This study generally supports the hypothesis that voice quality is an important enhancement cue for pitch range.
Spontaneous coronary artery dissection: contemporary aspects of diagnosis and patient management

Spontaneous coronary artery dissection is an increasingly recognised cause of acute coronary syndromes, especially in young and middle-age women. Recognising its particularities and differences with atherosclerotic disease is central for appropriately identifying and approaching these patients. The authors review the current state of knowledge on spontaneous coronary artery dissection and provide practical recommendations for the diagnosis and management of this condition, both in the acute and convalescence phases.
YENDO MÁS ALLÁ DE LA LÓGICA CLÁSICA PARA ENTENDER EL RAZONAMIENTO EN EDUCACIÓN MATEMÁTICA

La evidencia experimental acumulada en las últimas décadas en la literatura psicológica muestra que la interpretación y uso de los conectivos lógicos en distintos contextos están lejos de ser obvios. Estos resultados son a menudo interpretados sólo como una falta respecto a una única lógica tomada como normativa. Esto mismo ocurre muy frecuentemente en la literatura de Educación Matemática en donde los parámetros de análisis del razonamiento presente en los estudiantes se limitan al ámbito de los conectivos y eventualmente los cuantificadores clásicos. Es posible, sin embargo, considerar otro tipo de lógicas que puedan ayudarnos no solo a reconsiderar esta perspectiva, sino a entender mejor cómo razonamos y por qué algunos “errores” lógicos en Matemáticas son tan consistentemente frecuentes. Proponemos un examen de los resultados de investigación de distintos experimentos y de la literatura, a la luz de algunas herramientas lógicas, en particular de algunas lógicas computacionales no monotónicas.
Age and sex variation in the distribution of visceral fat among healthy doctors

Background: Non Communicable Diseases (NCDs) are a mushrooming problem and accounts for majority of deaths. Paradoxically the population of Kerala is increasingly susceptible to NCDs despite having good access to health care. Doctors work in highly stressful conditions and often adopt sedentary lifestyles thereby forming a subset of the NCD prone population. The objective of this study was to assess the health status of the doctors which would provide an insight into their health and level of awareness regarding the role of lifestyle in prevention of NCDs.Methods: Sixty five doctors participated in this Cross-Sectional Observational study conducted at a CME in Kerala. After obtaining Institutional Ethical clearance, demographic profile was collected, and fat levels were estimated using body composition analyzer (OMRON-HBF375). The results were tabulated using Microsoft Office Excel, analyzed using SPSS version 20.Results: On classifying the study group based on BMI, only 34 were normal, 26 were Overweight, and 4 were Obese. Gender wise distribution of body fat revealed only 4 had normal body fat composition. The study also showed that as age advances the amount of total and visceral fat shows a significant upward trend in males.Conclusions: BMI alone cannot be used as a predictor of health status. Body Fat percentage analysis should be included in routine screening programs. Men have a tendency to develop visceral adiposity with age. Females depend more on fat as primary source and hence females will respond better to a properly programmed exercise regime and men to a well guided diet program with exercise.