Miracle-dz/UniFAR-FTUs huggingface dataset:
Atomic Norm Denoising In Blind Two-Dimensional Super-Resolution

In this work, we develop a new framework for denoising in blind two-dimensional (2D) super-resolution that recovers a set of 2D continuous parameters as well as unknown waveforms from noisy samples. We apply the atomic norm to de-noise a weighted sum of time-delayed and frequency-shifted unknown waveforms. Moreover, we derive the theoretical mean-squared error of the estimator, and we show that it depends on the noise level and other system parameters. Then, we prove that when the number of samples satisfies certain bound, we can recover all the unknowns with high probability. Finally, we verify our theoretical findings using simulations.
Les protéines chaperonnes Hsp60 et Grp78 : localisation dans les spermatozoïdes, le système reproducteur de la femme et leurs effets sur les différentes fonctions des spermatozoïdes humains

Sperm capacitation is a prerequisite to ensure internai fertilization. In vivo, this process occurs in the female génital tract where sperm cells interact with oviduct epithelial cells as well as their sécrétions. Thèse interactions allow to spermatozoa to maintain and promote their capacity of achieving fertilization. Endogenous sperm proteins also contribute to the success of fertilization. They sustain the possibility to obtain a compétent sperm cell able to interact and fuse with the egg. The présent study investigates the présence of Hsp60 and Grp78 in spermatozoa and female reproductive tract as well as the effect of commercial recombinant exogenous Hsp60 and Grp78 on human sperm functions in vitro.
Efectos tóxicos de la exposición aguda de Prochilodus magdalenae a cloruro de mercurio

Alevinos de Prochilodus magdalenae (bocachico), adquiridos en cultivos de peces, fueron expuestos durante 96 horas a cinco concentraciones agudas de mercurio (0.1, 0.13, 0.17, 0.22, 0.29 mg/l) en un sistema estático con renovación a las 48 horas. Durante la aclimatación los peces se mantuvieron en agua de consumo declorinada filtrada con carbón activado. La tasa de recirculación del agua fue 50 min y los niveles de oxígeno fueron superiores a 80% de saturación. Los peces fueron alimentados diariamente con Tetramin y el suministro de alimento se interrumpió doce horas antes del inicio de los experimentos. Durante la aclimatación y las pruebas de toxicidad la temperatura, el pH y el oxígeno disuelto variaron en un rango estrecho. La concentración letal media (CL50) del mercurio se calculó para 24, 48, 72 y 96 horas mediante los métodos promedio del ángulo móvil y probit. Los resultados a las 96 horas indicaron gran homogeneidad de la concentración letal media al variar entre 0.132 y 0.133 mg/l de cloruro de mercurio, y una menor sensibilidad de P. magdalenae que Poecilia reticulata a esta sustancia.
A STUDY ON OSTEOPOROSIS AND IMPACT OF DRUGS & EXERCISE FOR ITS CLINICAL MANAGEMENT

Aim: The purpose of study was “Prevention of an Osteoporosis by development of the intervention of education. To observe the severely affected bones due to rapid decline in BMD. Methods: all the data were collected after the patient counseling by the cross –sectional study in both sexes (n=163), aged 18 to 70 years, at CMHRC Hospital, Churu, India using random sample method. Individuals were classified as they having osteoporosis/ osteopenia characterized using T-Score after the DEXA scanning based on the WHO. Result: It was found that out of 58 patients 6, 24, 16 &12 patients of them were affected due to “wrong posture”, “Imbalanced diet, mineral & BMI” “Adverse drug reactions” & “Adverse effects of other associated disease”. Subjects with normal or lower BMI were more affected with osteopenia or initial stage of osteopenic fractures, when compared to overweight or obese patients. The sitting, sleeping & standing postures are to be altered while at work as they advance in age or in case of initial stage of osteopenic fractures. All the subjects are advised to follow the Posture related Education, Diet maintenance and required exercise to mimic the initial stage of osteopenia/osteoporosis and prevention of osteoporosis disorder. Significantly lower T-scores were observed at spine with (-) 2.05 ± 0.15 & hip bone with (-) 2.15 ± 1.25 respectively as compare to other bones either in men or women. That concludes that the susceptibility in the both spine and hip bone had rapid decline in the BMD instead of other bones. Keywords: BMD, T-score, Osteoporosis, Calcium supplements, skeletal disease, Osteopenia.
Influencers and targets on social media: Investigating the impact of network homogeneity and group identification on online influence

This study identifies social media users who aim to influence others and those who have experienced influencing behavior targeted at them. It investigates how influential users and targets of influence differ with respect to their demographic backgrounds and how the perceived group identification, network homogeneity, and size of the social network affect online influence. The data was based on a large-scale survey of Finnish people (N=2,761). We find that young and highly educated men were more likely to be targets of influence, but the demographic differences were less obvious with regard to influencing behavior. Moreover, group identification was a significant factor underpinning online influence for both influencing behavior and target experiences. The network homogeneity and the size of the network increased the likelihood of influencing behavior. Our main contribution is to shed light on people who are targets of online influencing on social media. By comparing influential users and their targets, this study extends the previous research, which has mostly focused on detecting influential people.
Reduced switching mode for SAR ADCs: analysis and design of SAR A-to-D algorithm with periodic standby mode circuit components

This study presents the analysis and design of reduced switching (RSw) activity mode successive approximation register (SAR) analogue-to-digital (A-to-D) algorithm. For given analogue-to-digital converter (ADC) specifications, RSw mode design is based on the observation that the signal variation in two successive samples becomes linear over a certain range of input frequencies. Hence, dispensable switching activity between the two samples can be eliminated by enabling periodic temporal reference to the converter. No prediction or logic circuitry is required to extract information from previous bits. However, there exists a trade-off between the input frequency and the sampling frequency. A design criterion is derived using numerical mathematics to skip evaluation of the optimum number of bits while maintaining the desired signal-to-noise and distortion ratio. The design criterion is validated through behavioural simulations using MATLAB/Simulink ® . Furthermore, a fully differential 10-bit, 104 kS/s ADC is designed in a standard 180 nm CMOS technology to demonstrate circuit implementation of the RSw mode. In the RSw mode, power dissipation in the comparator and relevant digital circuitry decreases by 20%. The ADC achieves low-frequency effective number of bits of 9.7 bits and spurious free dynamic range of 68.3 dB. With 1.8 V supply voltage, average power dissipation in the core ADC is 2.54 μW; resulting in figure-of-merit of 29.3 fJ/conv-step.
Interindividual Diversity in Expression of Organic Anion Uptake Transporters in Normal and Cirrhotic Human Liver

The liver plays an essential role in removing endogenous and exogenous compounds from the circulation. This function is mediated by specific transporters, including members of the family of organic anion transport proteins (OATPs) and the Na+‐taurocholate transporting polypeptide (NTCP). In the present study, transporter protein expression was determined in liver samples from patients with cirrhosis or controls without liver disease. Five transporters (OATP1A2, OATP1B1, OATP1B3, OATP2B1, and NTCP) were studied. Transporter content in homogenates of human liver was quantified on western blots probed with transporter‐specific antibodies in which a calibrated green fluorescent protein‐tagged transporter standard was included. Liver samples from 21 patients with cirrhosis (hepatitis C in 17 and alcohol abuse in 4) and 17 controls without liver disease were analyzed. Expression of each of the transporters had a large spread, varying by an order of magnitude in cirrhotic and control livers. OATP1B1 was the most abundant transporter in controls (P < 0.01) but was significantly lower in cirrhotic livers as was NTCP expression (P < 0.01). There was little difference in transporter expression with respect to age or sex. Despite the large variability in transporter expression within a group, analysis in individuals showed that those with high or low expression of one transporter had a similar magnitude in expression of the others. Conclusion: Differences in transporter expression could explain unanticipated heterogeneity of drug transport and metabolism in individuals with and without liver disease.
RISK ASSESSMENET AGAINST WESTERN CORN ROOTWORM Diabrotica virgifera virgifera LeConte IN THE MOSLAVINA REGION

Sirenjem kukuruzne zlatice Diabrotica virgifera virgifera LeConte podrucjem kontinentalne Hrvatske ugrožena je proizvodnja kukuruza. Rad je imao za cilj utvrditi dinamiku leta i visinu populacije u poljima ponovljene sjetve i prve godine kukuruza pracenu Pherocon AM (PhAM) žutim plocama i feromonskim mamcima tijekom 2007. godine na podrucju Moslavine i temeljem procijenjene visine populacije procijeniti rizik za ponovljenu sjetvu U istraživanje je bilo ukljuceno 8 polja, 4 polja ponovljene sjetve kukuruza i 4 polja prvi puta sjetve kukuruza. U 3 polja ponovljene sjetve i 3 polja prve godine kukuruza postavljene su PhAM žute ploce. U jedno polje ponovljene sjetve i jedno polje prve godine kukuruza postavljen je feromonski mamac.Let kukuruzne zlatice u 2007. godini na podrucju Moslavine je trajao kratko. Uzrok tome visoke su temperature zraka zabilježene tijekom 2007. godine, a uzrokovale su brži razvoj pojedinih razvojnih stadija. Utvrđeno je da je populacija zlatica na vecini polja bila niska i da su maksimalni tjedni ulovi bili 1/zlatica/PhAM/7dana sto je niska gustoca populacije stetnika, ispod razine ekonomskog praga tolerantnosti. Maksimalni ulovi zabilježeni su u srpnju. Na jednom polju ponovljene sjetve zabilježen je ulov od 45.66zlatica/PhAM/7dana sto je iznad praga tolerantnosti. Na tom polju utvrđen je rizik od stete za ponovljenu sjetvu kukuruza u 2008. godini. Niti na jednom polju nisu zabilježene stete od licinke. Na feromonskim mamcima zabilježen je visok ulov usprkos kratkom periodu pracenja, sto govori o visokoj brojnosti kukuruzne zlatice na podrucju na kojem je proveden monitoring.
Thin-film flip-chip UVB LEDs realized by electrochemical etching

We demonstrate a thin-film flip-chip (TFFC) light-emitting diode (LED) emitting in the ultraviolet B (UVB) at 311 nm, where substrate removal has been achieved by electrochemical etching of a sacrificial Al 0.37 Ga 0.63N layer. The electroluminescence spectrum of the TFFC LED corresponds well to the as-grown LED structure, showing no sign of degradation of structural and optical properties by electrochemical etching. This is achieved by a proper epitaxial design of the sacrificial layer and the etch stop layers in relation to the LED structure and the electrochemical etch conditions. Enabling a TFFC UV LED is an important step toward improving the light extraction efficiency that limits the power conversion efficiency in AlGaN-based LEDs.
GC And FTIR Studies Of Hexane and Ethanol Extracts of Calophyllum Inophyllum, Nigeria

This study investigates the phytochemical constituents in ethanol and hexane seed extract of Calophyllum inophyllum. The seed extracts contains saponins, tannins, glycosides, flavonoids, and steroids and absence of alkaloids and anthraquinones. The FTIR study shows various absorptions in the two extracts of Callophylum inophyllum. A strong absorption at 3265.3 cm-1 corresponds to O-H stretch which was observed in the ethanol extract only. C=O stretch was observed in 1742.5 cm-1 and 1701.5 cm-1 in both extracts. Other strong absorptions were observed at 2853.3 cm-1, 2929.7 cm-1, 2922.2cm-1, 2976.3 cm-1, 1578.5 cm-1, 1459.3 cm-1, 1347.4 cm-1, 1235.6 cm-1 and 1312.0 cm-1 in both extracts. 1407.1cm1, 1449.9cm-1 and 1116.3cm-1 in the ethanol extract only. 3006.1 cm-1, 1654.9cm-1, 1625.1 cm-1, and1377.3 cm-1 in hexane extract only. 1079.1 cm-1, 1097.7 cm-1,1118.2 cm-1 and 1159.2 cm-1 in both extracts. Other absorptions observed are 1039.9 cm-1,855.2 cm-1, 721.2 cm-1, 928.1 cm-1, 885.2 cm-1, and 697.0 cm-1. Gas Chromatography analysis identified the presence of eight fatty acids in Calophyllum inophyllum seed extract namely: Lauric (3.19%), Pentadecanoic (0.3%), Stearic (8.03%), Oleic (17.63%), Linoleic (16.67%), Arachnidic (0.2%), Behenic (0.05%), Lignoceric (0.04%) and absence of Tridecanoic, Myristic, Palmitic, Tricosnoic. This study concludes that the seed extracts of Calophylluminophyllum contain large amounts of phytochemicals and beneficial fatty acids with a possibility of wide range application taking advantage of the biological activities such as antimicrobial, antiviral, cytotoxic, analgesic and against other disorders in favor of public health.
Human papillomavirus genotype profiles and cytological grades interlinkages in coinfection with HIV

Introduction The study aimed to examine and characterize human papilloma virus (HPV) cytological grade trends and genotypes among HPV/HIV co-infected/cases and HPV monoinfected/control women attending Kisii Teaching and Referral Hospital, Kenya. Methods HIV positive co-infected with HPV (HPV/HIV) and HIV negative women monoinfected with HPV profiled as co-infected/cases and monoinfected/control arms respectively were enrolled. HPV subtypes were assayed by Xpert® HPV system (GXHPV-CE-10) alongside pathological cytology analysis of cervical tissue samples. Results Low grade intraepithelial lesion (LSIL) was the most predominant cytological grade across cases and controls with a prevalence of 32 (38.1%) while high grade squamous intraepithelial lesion (HSIL) was highest among HPV/HIV co-infected with a prevalence of 23 (27.38%). Among the monoinfected (controls) the predominant lesion was low grade intraepithelial lesions (LSIL) with a prevalence of 23 (27.38%). HPV type 16 had the highest prevalence 26 (30.8%) among the VIA positive women in the overall study participants followed by combinations of HPV types (16, 18/45) at 19 (22.6%). Conclusion High risk HPV types 16 and 18/45 were the most predominant in the established cytological grades and among the co-infected women. Routine screening using both cytological and HPV testing should be embraced and/or reinforced as early screening and preventive strategies in the covered geographical region population. Provision of the currently available vaccines to these women at an early age would provide effective protection since the HPV type profiles in this population are covered by such vaccines.
ASSESSMENT OF NEONATAL CARE SERVICES BY NURSES IN TERTIARY HEALTH INSTITUTIONS IN SOUTH EASTERN NIGERIA

Survival of the newborn demands care by professionals who are sound in knowledge and practice of neonatal care so as to give quality care. This study focused on assessment of neonatal care services by nurses in tertiary health institutions in South Eastern Nigeria. It was a descriptive cross-sectional research design. Multistage sampling technique was used to select 440 nurse respondents for the study. Two research questions and one null hypothesis guided the study. The Instruments used for data collection were questionnaire on neonatal care services by nurses in tertiary health Institutions and checklist on assessment of available and functional equipment, drugs and nursing staff strength in tertiary health institutions. Standard descriptive statistics of frequency distribution, mean and standard deviation were used to summarize the variables and answer the research questions. Kruskal Wallis test was used in testing the null hypothesis at 0.05 level of significance. The result indicated good quality of neonatal care given by nurses in the tertiary health institutions (mean =2.88; SD = 0.69). There was generally poor attitude by the nurses (mean = 2.42; SD = 0.38). Staff strength of the nurses significantly influenced the attitude displayed by the nurses in their care of the neonates (x2= 9.293; p-value = 0.026).
COMUNIDADES PÚBLICAS DE APRENDIZAGEM EM REDE: UM ESTUDO DE CASO

Este artigo tem como base um estudo que foi feito sobre as novas comunidades de aprendizagem em rede que estao surgindo em espacos publicos em rede – mais especificamente, a plataforma de sites de perguntas e respostas Stack Exchange, em comparacao com os espacos virtuais mais tradicionais que sao os ambientes virtuais de aprendizagem (AVAs). Foi realizada uma pesquisa etnografica por meio de observacao participante sobre algumas comunidades da plataforma Stack Exchange, particularmente a do site "Stack Overflow em Portugues" (um site sobre programacao de computadores) e a do site "Portuguese Language". Um dos pesquisadores participou como usuario desses sites por um ano, fazendo as observacoes e anotacoes necessarias sobre as respectivas comunidades, sobre os seus padroes de identidade, como os usuarios participam, como o conhecimento e construido, e como todas essas atividades se diferenciam do que acontece normalmente nos AVAs. Este e um objeto de pesquisa ainda relativamente novo, sobre o qual nao se produziram muitos estudos. Alem de relatar a experiencia da participacao em comunidades virtuais de aprendizagem, a importância de estudos como esse pode vir das questoes que essas experiencias suscitam. O trabalho pode tambem contribuir com ideias e conhecimentos que mostrem ao leitor os varios significados dos fenomenos analisados, motivando estudos futuros.
Improvement of Shaped Charge Penetration Capability and Disturbation of the Jet by Explosive Reactive Armor

: This paper presents a numerical study of the effect of main parameters (liner material, explosive charge, stand-off distance and the presence of the wave-shaper), on one hand, on the jet formation, jet velocity and the jet length, and on the other hand, on the penetration depth. We propose a numerical approach to evaluate their effects on the performance of the shaped charge. AUTODYN - 2D software is used for numerical simulations of the shaped charge. The multi material Euler solver of the AUTODYN is used for the jet formation investigation, whereas, Lagrange solver is used for the resolution of the penetration problem. Results have shown that the presence of wave-shaper increases the shaped charge depth penetration. For the standoff of 6 charge calibres, the jet penetration is found to be deepest. It is found that the jet velocity is proportional to the jet energy, and the penetration is proportional to the liner density. The oblique explosive reactive armor is more efficient for the protection of the main target. Numerical results have a good agreement with the data from available literature – with experimental results for the chosen explosives.
Antioxidant and Anti-hyperlipidemic Effects of Bark Extract of Pinus eldarica in Dexamethasone-induced Dyslipidemic Rats

Background & Objective: Although Pinus eldarica is considered as a pine with many valuable phytochemical constituents, little is known about the pharmacological effects of its bark extract. Therefore, the present study aimed to evaluate in vivo antioxidant activity and also the possible beneficial effects of the bark extract of P. eldarica on dexamethasone-induced dyslipidemia in rats. Materials & Methods: Total phenolic content was determined using Folin-Ciocalteu method. The in vivo antioxidant assays included the measurement of hydroperoxides level and ferric reducing antioxidant power (FRAP) value in plasma samples of rats receiving intraperitoneal injections (IP) injections of plant extract (100, 200 and 400 mg/kg) for 28 days. For induction of dyslipidemia, dexamethasone (10 mg/kg) was subcutaneously administered during 8 days. Different doses of extract were given orally plus dexamethasone in three groups of animals. Serum lipids, blood glucose and malondialdehyde (MDA) levels and liver histopathology were assessed. Results: High total phenolic content was determined as 375±1.2 mg gallic acid equivalent/ g of dried bark extract. The extract significantly decreased plasma hydroperoxides level at all doses and increased FRAP value at the dose of 400 mg/kg during in vivo antioxidant analysis. P. eldarica led to a significant reduction in serum levels of blood glucose, total cholesterol, triglyceride and MDA and improved liver histopathological changes at the doses of 200 and 400 mg/kg in dyslipidemic rats. Conclusion: These findings suggest the potential antioxidant, antihyperlipidemic and antihyperglycemic activities for the bark extract of P. eldarica which may be due to the high amounts of phenolic compounds.
Ion Channels: From Atomic Resolution Physiology to Functional Genomics

Introduction: stretching the envelope in structure-function studies of ion channels (M. Sansom) Structure of acetylcholine-gated channel (N. Unwin) The 2.7 A structure of AChBP, homologue of the ligand-building domain of the nicotonic acetylcholine receptor (K. Brejc, et al.) The architecture of a water-selective pore in the lipid bilayer visualized by electron crystallography in vitreous ice (A. Mitra, et al.) The structure of Glpf, a glycerol conducting channel (D. Fu, et al.) Water in ion channels and pores-simulation studies (M. Sansom, et al.) What can be deduced about the structure of Shaker from available data? (B. Roux) Permeation energetics in a model potassium channel (S. Garofoli, et al.) The beta subunit of Kv1 channels: voltage-gated enzyme or safety switch? (J. Gulbis) EPR approaches to ion channel structure and function (E. Perozo, et al.) Excitability is mediated by the T1 domain of the voltage-gated potassium channel (S. Choe, et al.) Structural organization of the voltage sensor in voltage-dependent potassium channels (D. Papazian, et al.) Electron diffraction of a bacterial CIC -type chloride channel (M. Pirruccello, et al.) A protein chemical approach to channel structure and function: the proton channel of the vacuolar H+-ATPase (J. Findlay and M. Harrison) Acetylcholine receptors, between closed and open (A. Auerbach) Functional genomics of ionotropic acetylcholine receptors in Caenorhabditis elegans and Drosophilia melanogaster (D. Satelle et al.) Final General Discussion Index of Contributors Subject Index