Miracle-dz/UniFAR-FTUs huggingface dataset:
Pain Pressure Threshold in the Region of the Sacroiliac Joint in Patients Diagnosed with Sacroiliac Joint Pain.

BACKGROUND Although the prevalence of sacroiliac joint (SIJ) pain is relatively high (15 - 30%), there is no unambiguous reference standard to diagnose SIJ pain. Pressure tenderness in the SIJ region is used for diagnostic purposes, but the clinimetric properties of this procedure remain to be determined. OBJECTIVES The aim of this study is to determine the reliability of pain pressure threshold (PPT) measurements in the SIJ region and the difference in PPTs in the SIJ region between healthy volunteers and PPTs in patients with SIJ pain. STUDY DESIGN Prospective cohort study. SETTING Outpatient pain clinic VU University Medical Center. METHODS Forty-one healthy volunteers and 31 patients diagnosed with SIJ pain were included. PPTs were obtained from 5 measurement points in the region of the SIJ with a pressure pain algometer using a standardized protocol. The inter-rater reliability of this method was calculated by means of the Intraclass Correlation Coefficients (ICC) of individual assessment performed by 2 individual raters of SIJs of healthy volunteers on both sides. PPTs of healthy volunteers were compared to those of the affected side in patients with SIJ pain. RESULTS PPT measurement showed moderate to good inter-rater reliability (ICC 0.6 - 0.82). The median PPTs of 5 points was comparable for both sides in healthy volunteers (right: 8.5 kg/cm2 [IQR 6.0 - 10.0]; left 8.3 kg/cm2 (5.8 - 10.0]). Median PPTs for the affected sides of patients with SIJ pain were significantly lower compared to the same side of healthy volunteers (right: 2.4 kg/cm2 [IQR 2.2 - 3.2, n = 15]; left: 2.5 kg/cm2 [2.3 - 3.2, n = 16]; P < 0.001 for both sides). LIMITATIONS Only the SIJ on one side of was measured in patients with SIJ pain, where both sides would be desirable. CONCLUSIONS Pressure pain algometry appears to be a reliable method to establish differences in PPTs between healthy volunteers and patients with SIJ pain. The diagnostic accuracy of this test should be investigated further.
DeyPos: For multi-users environments using MD5

Dynamic Proof of Storage (PoS) is a conducive cryptographic rudimentary technology that empowers a client to cohere the respectability of outsourced and in addition insourced records and to proficiently refresh the documents in a server. A multi-client needs the protected customer side cross-client replica method, enabling a client to avoid the transferring procedure, when different proprietors of similar documents have transferred them to the server. Application gives an adaptable and helpful route for information sharing, which brings different advantages for both the general public and people. Be that as it may, there exists a characteristic protection for clients to straightforwardly outsource and insource the common information to the server since the information regularly contain profitable data. It is important to put cryptographically upgraded get to control on the mutual information. Character based encryption is a promising cryptographical primitive to assemble a handy information sharing framework.
The measurement of collagenase, tissue inhibitor of metalloproteinases (TIMP), and collagenase-TIMP complex in synovial fluids from patients with osteoarthritis and rheumatoid arthritis.

OBJECTIVE To compare the levels of collagenase, tissue inhibitor of metalloproteinases (TIMP), and collagenase-TIMP complex in synovial fluid (SF) from patients with rheumatoid arthritis (RA) and patients with osteoarthritis (OA). This study aims to clarify existing data from previously used enzyme or inhibitor activity assays performed following separation by gel filtration, by using a 1-step enzyme-linked immunosorbent assay (ELISA) for each component. METHODS Total collagenase, free TIMP, and collagenase-TIMP complex were measured using a newly developed, specific double-antibody sandwich ELISA: RESULTS Levels of both collagenase and TIMP were significantly higher in RA patients (collagenase 1,560 +/- 150 ng/ml [mean +/- SEM], TIMP 1,610 +/- 130 ng/ml; n = 80) than OA patients (collagenase 420 +/- 90 ng/ml, TIMP 1,050 +/- 60 ng/ml; n = 80), with the difference being especially striking for collagenase. Sixteen RA fluids had detectable levels of collagenase-TIMP complex, compared with only 3 OA fluids. CONCLUSION The level of total collagenase in SF is greater in RA than OA, while levels of free TIMP show more overlap between the 2 diseases; this may simply reflect the increased inflammation seen in RA, or it may reflect a different disease mechanism.
A mammalian inhibitory GDP/GTP exchange protein (GDP dissociation inhibitor) for smg p25A is active on the yeast SEC4 protein

Evidence is accumulating that smg p25A, a small GTP-binding protein, may be involved in the regulated secretory processes of mammalian cells. The SEC4 protein is known to be required for constitutive secretion in yeast cells. We show here that the mammalian GDP dissociation inhibitor (GDI), which was identified by its action on smg p25A, is active on the yeast SEC4 protein in inhibiting the GDP/GTP exchange reaction and is capable of forming a complex with the GDP-bound form of the SEC4 protein but not with the GTP-bound form. These results together with our previous findings that smg p25A GDI is found in mammalian cells with both regulated and constitutive secretion types suggest that smg p25A GDI plays a role in both regulated and constitutive secretory processes, although smg p25A itself may be involved only in regulated secretory processes. These results also suggest that a GDI for the SEC4 protein is present in yeast cells.
Animal models for studying epithelial barriers in neonatal necrotizing enterocolitis, inflammatory bowel disease and colorectal cancer

ABSTRACT The intestinal epithelial cells line the luminal surface of the entire gastrointestinal tract which is crucial for the absorption of nutrients and prevention of pathogens entering from the external environment. The epithelial barrier plays an important role in organ development, disease pathogenesis, and aging. The major component of an epithelial barrier is the single columnar epithelium and tight junctions. Tight junctions are located at the most apical region of the junctional complex and contain many integral membrane proteins, such as occludin, the claudin family, and junctional adhesion molecules (JAMs). The disruption of intestinal epithelial barriers may lead to several pathophysiological conditions causing malabsorption of nutrition and chronic inflammation. In this review, we provide an update on the alterations of epithelial barriers associated with gut diseases using experimental animal models; we appraise the role of tight junctions in neonatal necrotizing enterocolitis (NEC), inflammatory bowel disease (IBD), and colorectal cancer; we also compare some common features as well as differences and similarities in the pathophysiology of intestinal inflammation in neonatal (NEC) and adult (IBD) gut.
A comparative study of coreless and conventional axial flux permanent magnet synchronous machines for low and high speed operation

Axial Flux Permanent Magnet (AFPM) motors of two types, coreless and conventional topologies, have been studied in order to identify their merits and drawbacks at different ratings, particularly for in-wheel electric transportation applications. The performance of the coreless with several slotpole combinations and number of disks is evaluated. Design of experiments (DOE) methodology is utilized to determine the correlation between input variables and output parameters and the regression models are used to identify the optimum design. Detailed comparison between coreless and conventional topologies at two operating speeds at extreme ends of the driving cycle are conducted.
Analysis on causal relationship of electrical activations in response to emotional stimulus

Most of the recent researches mainly have considered causal relationships between activation of different brain regions, and concentrated on development of new techniques for this purpose. Strength, direction and origin of activation between two or more electrodes were assessed in these studies. However, methodological limitations cause lack of sufficient results for understanding of these causal relationships between activated electrodes. Coherence computations were generally performed with EEG recordings during resting state with eyes open and closed, or during sleep in many studies. On the other hand, there are lack of information about the coherence of neural activations as a response to emotional stimuli. Thus, the main aim of this study is to investigate causal relationship between activations of different electrodes during presentation of an emotional stimuli. In this context, three sets of emotional videos (positive, negative, and neutral) were used as stimuli, and the data were used in computation of coherence.
Vitamin K in human milk—still not enough

The breastfed infant has limited sources of vitamin K, as it is transmitted poorly across the placenta and is present in very low concentrations in human milk. The author of this paper reports a concentration of vitamin K in human milk (0.517 ±; 1.521 μ‐g/dl) that is about twice the average of earlier reports (0.25 μg/dl). About half of the increased concentration (0.235 ±; 0.144 μ/dl) is accounted for by vitamin K2 (menaquinone) rather than vitamin K1 (phylloquinone); the latter generally thought to be more important in human nutrition. The significance of these findings is discussed.
Renal Artery Imaging: A Prospective Comparison of Intra-Arterial Digital Subtraction Angiography with Conventional Angiography

This study describes a systematic comparison of intra-arterial digital subtraction angiography (DSA) of the main renal arteries with conventional angiography (CA), the currently accepted "gold standard" for the diagnosis of renal artery stenosis. Twenty-five patients scheduled for abdominal aortography for various indications underwent first DSA then CA. The DSA and CA images were evaluated for number of renal arteries, presence and grade of renal artery stenosis, presence of post-stenotic dilation or fibromuscular changes, and diagnostic and pictorial adequacy of the images. DSA was found to be diagnostically adequate in 92 % of cases, compared with 96 % for CA. In evaluating significant main renal artery stenosis, which the authors assumed to be any stenosis greater than 50%, there were 10 such stenoses seen by CA. DSA also detected 10 cases, but there was 1 false positive and 1 false negative, yielding a sensitivity of 90 % and a specificity of 98%. There was also close correlation of DSA and CA for the few cases of post-stenotic dilatation and fibromuscular dysplasia encountered. The authors conclude that DSA is an acceptable substitute for CA in the evaluation of patients for main renal artery stenosis.
A study of socialization and job satisfaction of faculty at an urban two-year community college /

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Qatar Emerging as the Most Attractive FDI Destination in the GCC

In this era of globalization and high competition each and every nation is trying to attract maximum investments from overseas for the development and growth of the economy. All GCC economies are in the growth mode and are dependent on the revenue from oil, but the current decline in oil prices have very badly affected these economies and all are targeting to secure maximum foreign direct investments (FDI). Many of the developed nations and Multinational Corporations are in the search of the best destinations for their investments. The purpose of this study is to identify the most attractive destination for FDI in the GCC. The flow of FDI into a country depends on the availability of a number of factors. This study probes into the existence of each of these factors in the various GCC countries. Secondary data is used to rank each country on the basis of the parameters that attract FDI. The findings indicate that Qatar is emerging as the most attractive FDI destination in the GCC. This paper is useful for all countries and MNCs who are searching for investment destinations in the GCC as it ranks the countries on the basis of the attractiveness of various determinants of FDI.
Characterization of a new pathway for epichlorohydrin degradation by whole cells of xanthobacter strain py2

The degradation of epichlorohydrin (3-chloropropylene oxide or 1-chloro-2,3-epoxypropane) by whole-cell suspensions of Xanthobacter strain Py2 was investigated. Cell suspensions prepared from cultures grown with propylene as the carbon source readily degraded epichlorohydrin. The ability to degrade epichlorohydrin correlated with the expression of enzymes involved in alkene and epoxide metabolism, since cell suspensions prepared from cultures grown with glucose or acetone, in which the enzymes of alkene and epoxide oxidation are not expressed, did not degrade epichlorohydrin. The alkene monooxygenase-specific inhibitor propyne had no effect on the degradation of epichlorohydrin, demonstrating that alkene monooxygenase is not involved in epichlorohydrin conversion. The interaction of epichlorohydrin and epibromohydrin with the epoxidase which catalyzes aliphatic epoxide conversions was established by showing that the epihalohydrins were specific and potent inhibitors of propylene oxide-dependent O(inf2) consumption by cell suspensions. The rates of degradation of epoxides in whole-cell suspensions decreased in the series propylene oxide > epifluorohydrin > epichlorohydrin > epibromohydrin. The pathway of epichlorohydrin degradation was investigated and found to proceed with stoichiometric dechlorination of epichlorohydrin. The first detectable product of epichlorohydrin degradation was chloroacetone. Chloroacetone was further degraded by the cell suspensions, and in the process, acetone was formed as a nonstoichiometric product. Acetone was further degraded by the cell suspensions with enzymes apparently induced by the accumulation of acetone. The metabolism of allyl chloride (3-chloropropylene) by propylene-grown cells was initiated by alkene monooxygenase and proceeded through epichlorohydrin, chloroacetone, and acetone as intermediate degradation products. These studies reveal a new pathway for halogenated epoxide degradation which involves halogenated and aliphatic ketones as well as other unidentified intermediates and which is unique from previously characterized hydrolytic degradative pathways.
U.S. Teachers' Perceptions of School Violence Prevention Programs

U.S. Teachers’ Perceptions of School Violence Prevention Programs by Natakie Chestnut MEd, Cheyney University, 2004 MS, Cheyney University, 2001 BA, Cheyney University, 2000 Doctoral Study Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Education Walden University May 2016
Automatic Target Recognition of Military Vehicles With Krawtchouk Moments

The challenge of automatic target recognition of military targets within a synthetic aperture radar scene is addressed in this paper. The proposed approach exploits the discrete-defined Krawtchouk moments, which are able to represent a detected extended target with few features, allowing its characterization. The proposed algorithm provides robust performance for target recognition, identification, and characterization, with high reliability in the presence of noise and reduced sensitivity to discretization errors. The effectiveness of the proposed approach is demonstrated using the MSTAR dataset.
Cyber Security & Ethical Hacking For SMEs

Literature posits that 30,000 SME websites are hacked daily. Thus it is acknowledged that web-based tools are essential to prevent cyber criminals hacking into online networks to comprise their services and gain access to confidential data for improper purposes. We consider the concept of Ethical Hacking where authorized hackers attempt to infiltrate a business's systems/networks on behalf of the owners with the intention of finding security weaknesses. However such security measures are costly and many SMEs lack the knowledge and resources to accomplish this. Utilizing an SME case study we provide insights into how Ethical Hacking, in the form of Penetration Testing using free open source tools, can be used by SMEs to protect their network's services/operations. Using Nmap, Google Hacking, Nessus and Brutus we uncovered 232 network vulnerabilities. Thus measures were put in to place to resolve these vulnerabilities and prevent the case study's sensitive data from future cyber threats.
An HTTP-based environmental monitoring system using power harvesting

This paper presents the development of an energy efficient environmental sensor that sends measurement data to a cloud platform using HTTP (Hypertext Transfer Protocol) requests. The device is based on a programmable system-on-chip (PSoC), and is equipped with a temperature and relative humidity sensor for taking measurements and with a WLAN (wireless local area network) module for sending data to the server. The main characteristics of the device consist in low power consumption, robustness and small dimensions. The developed sensor node supports the addition of power harvesting elements and this possibility was evaluated. Testing showed that energy autonomous wireless sensors using HTTP-based services represent a feasible solution for environmental monitoring applications in the context of Internet-of-Things (IoT).
Echinococcus metacestodes as laboratory models for the screening of drugs against cestodes and trematodes

SUMMARY Among the cestodes, Echinococcus granulosus, Echinococcus multilocularis and Taenia solium represent the most dangerous parasites. Their larval stages cause the diseases cystic echinococcosis (CE), alveolar echincoccosis (AE) and cysticercosis, respectively, which exhibit considerable medical and veterinary health concerns with a profound economic impact. Others caused by other cestodes, such as species of the genera Mesocestoides and Hymenolepis, are relatively rare in humans. In this review, we will focus on E. granulosus and E. multilocularis metacestode laboratory models and will review the use of these models in the search for novel drugs that could be employed for chemotherapeutic treatment of echinococcosis. Clearly, improved therapeutic drugs are needed for the treatment of AE and CE, and this can only be achieved through the development of medium-to-high throughput screening approaches. The most recent achievements in the in vitro culture and genetic manipulation of E. multilocularis cells and metacestodes, and the accessability of the E. multilocularis genome and EST sequence information, have rendered the E. multilocularis model uniquely suited for studies on drug-efficacy and drug target identification. This could lead to the development of novel compounds for the use in chemotherapy against echinococcosis, and possibly against diseases caused by other cestodes, and potentially also trematodes.
Initial Invasion of Gametophytic Self-Incompatibility Alleles in the Absence of Tight Linkage between Pollen and Pistil S Alleles

In homomorphic self-incompatibility (SI) systems of plants, the loci controlling the pollen and pistil types are tightly linked, and this prevents the generation of compatible combinations of alleles expressing pollen and pistil types, which would result in self-fertilization. We modeled the initial invasion of the first pollen and pistil alleles in gametophytic SI to determine whether these alleles can stably coexist in a population without tight linkage. We assume pollen and pistil loci each carry an incompatibility allele S and an allele without an incompatibility function N. We assume that pollen with an S allele are incompatible with pistils carrying S alleles, whereas other crosses are compatible. Ovules in pistils carrying an S allele suffer viability costs because recognition consumes resources. We found that the cost of carrying a pistil S allele allows pollen and pistil S alleles to coexist in a stable equilibrium if linkage is partial. This occurs because parents that carry pistil S alleles but are homozygous for pollen N alleles cannot avoid self-fertilization; however, they suffer viability costs. Hence, pollen N alleles are selected again. When pollen and pistil S alleles can coexist in a polymorphic equilibrium, selection will favor tighter linkage.
The Island Syndrome in Rodent Populations

Populations of rodents isolated on islads often show systematic differences in demography, reproduction, behavior, and morphology when compared to mainland populations. These differences, termed the island syndrome, include higher and more stable densities, better survival, increased body mass, and reduced aggressiveness, reproductive output, and dispersal. We synthesize information in the literature on island rodent populations and construct a conceptual model to explain in the island syndrome. Population density and other manifestations of the islands syndrome are predicted to increase with island isolation and to decrease with island area. The effect of isolation is direct by limiting dispersal, while the effect of area is less direct. As area increases, predators, competitors, and habitat structure increase in diversity. We suggest that the intensity or absense of density-depressing factors (primarily predation in communities comprised of only a few morphologically and trophically divergent species) is primarily responsible for the area effect and serves as a principal factor differentiating island from mainland populations of rodents. Other characteristics associated with the island syndrome may be the result of both short-term and long-term processes or responses. Short-term responses include reproductive, body size, and behavioral changes that may be phenotypic reaction norms in response to higher island densities. Thus, higher densities lead to reduced reproductive output, which then leads to greater body size. Initial behavioral differences may be owing to better survival and reduced dispersal, which result in less population turnover, greater neighbor familiarity, and less aggression. Long-term changes may be due to directional selection for reduced dispersal, increased body size in response to increased intraspecific competition, reduced reproductive output (smaller litters and delayed maturation) in response to reduced mortality schedules, and reduced aggressiveness. While the model is specific to rodent populations, the conclusions may be applicable to other systems if characteristic such as body size, vagility, and community composition are considered.