Miracle-dz/UniFAR-FTUs huggingface dataset:
AD Award Number : DAMD 1703-1-0245 TITLE : Computerized Interpretation of Dynamic Breast MRI

In contrast-enhanced (CE) MRI of the breast, signal-intensity time curves have been proven useful in differentiating between benign and malignant lesions. Due to uptake heterogeneity in the breast lesion, however, the signal-intensity time curve obtained from a specific region in the lesion may outperform that from the entire lesion. In this study, we propose the use of fuzzy c-means (FCM) clustering algorithms to reveal different temporal patterns within the breast lesion. The algorithm finds fuzzy cluster centers (i.e., temporal patterns) and assigns membership values to each voxel. The temporal pattern with maximum initial enhancement is selected as the representative curve of the lesion and the thresholded membership map is the identified region of fast enhancement. The approach was applied to the analysis of 121 lesions (77 mahgnant and 44 benign). The resulting representative curves were classified with linear discriminant analysis (LDA). The differentiation performance of LDA output in leave-one-out cross evaluation was assessed using receiver operating characteristic (ROC) analysis. Our results show that the use of FCM significantly improved the performance of signal-intensity time curves in the task of distinguishing between malignant and benign lesions.
Outside-In Constructions of Organizational Legitimacy: Sensitizing the Influence of Evaluative Judgments Through Mass Self-Communication in Online Communities

This article aims to further the current discussions in organizational studies about the construction of organizational legitimacy. We examine the influence of mass self-communication—in particular, evaluative judgments, such as product reviews, made by citizens in online communities—on the construction of organizational legitimacy. We chose an interdisciplinary approach in which we evaluated 177 studies from the field of organizational and communication science, relying on organizational legitimacy and mass self-communication as combined theoretical backbones. Our analysis revealed three sensitizing concepts: (1) community-mediated constituency, (2) audience engagement dilemmas, and (3) influencer-generated legitimacy. Based on these sensitizing concepts, we discuss outside-in (audience- or influencer-driven) and inside-out (company-driven) perspectives on the construction of organizational legitimacy.
Hilinenult pöördunud südameinfarktihaigel tehtud edukas müokardi revaskulariseeriminetrombi aspiratsiooni ja kaetud stendiga. Haigusjuhu kirjeldus

Muokardiinfarkti haige kiire poordumise korral haiglasse kasutatakse soone avamiseks esmavalikuna angioplastikat (PTKA – perkutaanne transluminaalne koronaarangioplastika) stentimisega. Haige hilise poordumise korral on pargarteri oklusiooni piirkonnas kujunemas ulatuslik tromboos. Angioplastika kaigus soone mehaaniline rekanaliseerimine pohjustab enamasti trombimasside distaalse embolisatsiooni ning seelabi nii antegraadse voolu lakkamise kui ka retrograadsete avanenud kollateraalide oklusiooni. Kokkuvottes revaskulariseerimine sageli ebaonnestub ja halvemal juhul infarktikolle laieneb.Eesti Arst 2014; 93(6):339–341
Specialization of Regions and Universities: The New Versus the Old

This paper analyzes whether there is a correspondence between a university's research specialization and industrial specialization in the region hosting the university, and to what extent universities influence regional productivity. Moreover, the analysis seeks to answer if a difference can be detected between the influences of old and new universities on regional performance. To achieve this end we utilize a unique data set on spatially disaggregated data for Sweden in the period 1975–99. A two‐step Heckman regression analysis is implemented to examine whether universities' research specialization matches regional specialization in production as compared to the average region. The results suggest a correspondence in specialization, as well as positive productivity effects. However, there are also considerable differences across regions, albeit primarily unrelated to the age of the universities.
Mutation Operators in BPMN Model

Mutation Testing is a technique to evaluate quality of test cases in Software Testing. A tester injects some faults into a source code then tests the source code against the original test cases for evaluating the test case quality. Business Process Model and Notation (BPMN) is a business model and an executable model which can run on a model engine. However, there is some test case generation technique for testing the BPMN. While the generated test cases do not measure their quality, therefore we aim to apply the mutation testing for BPMN model. But the mutation testing cannot perform if there is no mutation operator. To apply the mutation testing for the BPMN model, this paper introduces 25 mutation operators for the BPMN model when the tester performs the mutation testing on the BPMN model.
PULP-HD: Accelerating Brain-Inspired High-Dimensional Computing on a Parallel Ultra-Low Power Platform

Computing with high-dimensional (HD) vectors, also referred to as hypervectors, is a brain-inspired alternative to computing with scalars. Key properties of HD computing include a well-defined set of arithmetic operations on hypervectors, generality, scalability, robustness, fast learning, and ubiquitous parallel operations. HD computing is about manipulating and comparing large patterns— binary hypervectors with 10,000 dimensions—making its efficient realization on minimalistic ultra-low-power platforms challenging. This paper describes HD computing’s acceleration and its optimization of memory accesses and operations on a silicon prototype of the PULPv3 4-core platform (1.5 mm2, 2 mW), surpassing the state-of-the-art classification accuracy (on average 92.4%) with simultaneous 3.7× end-to-end speed-up and 2× energy saving compared to its single-core execution. We further explore the scalability of our accelerator by increasing the number of inputs and classification window on a new generation of the PULP architecture featuring bit-manipulation instruction extensions and larger number of 8 cores. These together enable a near ideal speed-up of 18.4× compared to the single-core PULPv3.
First-year Analysis of the Operating Room Black Box Study.

OBJECTIVE To characterize intraoperative errors, events, and distractions, and measure technical skills of surgeons in minimally invasive surgery practice. BACKGROUND Adverse events in the operating room (OR) are common contributors of morbidity and mortality in surgical patients. Adverse events often occur due to deviations in performance and environmental factors. Although comprehensive intraoperative data analysis and transparent disclosure have been advocated to better understand how to improve surgical safety, they have rarely been done. METHODS We conducted a prospective cohort study in 132 consecutive patients undergoing elective laparoscopic general surgery at an academic hospital during the first year after the definite implementation of a multiport data capture system called the OR Black Box to identify intraoperative errors, events, and distractions. Expert analysts characterized intraoperative distractions, errors, and events, and measured trainee involvement as main operator. Technical skills were compared, crude and risk-adjusted, among the attending surgeon and trainees. RESULTS Auditory distractions occurred a median of 138 times per case [interquartile range (IQR) 96-190]. At least 1 cognitive distraction appeared in 84 cases (64%). Medians of 20 errors (IQR 14-36) and 8 events (IQR 4-12) were identified per case. Both errors and events occurred often in dissection and reconstruction phases of operation. Technical skills of residents were lower than those of the attending surgeon (P = 0.015). CONCLUSIONS During elective laparoscopic operations, frequent intraoperative errors and events, variation in surgeons' technical skills, and a high amount of environmental distractions were identified using the OR Black Box.
Poster: Live Path Control Flow Integrity

Per-Input Control Flow Integrity (PICFI) represents a recent advance in dynamic CFI techniques. PICFI starts with the empty CFG of a program and lazily adds edges to the CFG during execution according to concrete inputs. However, this CFG grows monotonically, i.e., invalid edges are never removed when corresponding control flow transfers (via indirect calls) become illegal (i.e., will never be executed again). This paper presents LPCFI, Live Path Control Flow Integrity, to more precisely enforce forward edge CFI using a dynamically computed CFG by both adding and removing edges for all indirect control flow transfers from function pointer calls, thereby raising the bar against control flow hijacking attacks.
Balanced Crystalloids Versus Saline for Perioperative Intravenous Fluid Administration in Children Undergoing Neurosurgery: A Randomized Clinical Trial

Background: Balanced crystalloid solutions induce less hyperchloremia than normal saline, but their role as primary fluid replacement for children undergoing surgery is unestablished. We hypothesized that balanced crystalloids induce less chloride and metabolic derangements than 0.9% saline solutions in children undergoing brain tumor resection. Methods: In total, 53 patients (age range, 6 mo to 12 y) were randomized to receive balanced crystalloid (balanced group) or 0.9% saline solution (saline group) during and after (for 24 h) brain tumor resection. Serum electrolyte and arterial blood gas analyses were performed at the beginning of surgery (baseline), after surgery, and at postoperative day 1. The primary trial outcome was the absolute difference in serum chloride concentrations (post-preop&Dgr;Cl−) measured after surgery and at baseline. Secondary outcomes included the post-preop&Dgr; of other electrolytes and base excess (BE); hyperchloremic acidosis incidence; and the brain relaxation score, a 4-point scale evaluated by the surgeon for assessing brain edema. Results: Saline infusion increased post-preop&Dgr;Cl (6 [3.5; 8.5] mmol/L) compared with balanced crystalloid (0 [−1.0; 3.0] mmol/L; P<0.001). Saline use also resulted in increased post-preop&Dgr;BE (−4.4 [−5.0; −2.3] vs. −0.4 [−2.7; 1.3] mmol/L; P<0.001) and hyperchloremic acidosis incidence (6/25 [24%] vs. 0; P=0.022) compared with balanced crystalloid. Brain relaxation score was comparable between groups. Conclusions: In children undergoing brain tumor resection, saline infusion increased variation in serum chloride compared with balanced crystalloid. These findings support the use of balanced crystalloid solutions in children undergoing brain tumor resection.
The Early Intervention of Hearing Loss in Adults

The National Institute of Deafness and Other Communication Disorders of the National Institutes of Health (NIDCD-NIH) reported that 37.5 million persons or 15% of the American population have some difficulty hearing. The prevalence of hearing loss increases with age, and 2% of persons 45 to 54 years old have significant hearing loss; this increases to 8.5% for those 55 to 65 years old, 25% for those 65 to 74 years old, and 50% for those older than 75 years. Normal hearing for adults has been defined as audiometric thresholds 20 dBHL for standard audiometric frequencies of 0.25 to 8 kHz. Only about one in five persons with sensorineural hearing loss (SNHL) seeks help for their problems, and some individuals wait 10 years or more from the time that they first notice a problem communicating before seeking help. Waiting long periods of time to address SNHL can negatively impact the health-related quality of life (HRQoL) of individuals and their families, and it is often associated with social isolation, increased rates of depression and anxiety, and lessened self-efficacy and mastery. Untreated SNHL also is linked to hastened cognitive decline in elderly persons living independently and with global brain atrophy, particularly in the temporal lobe. Possible reasons for persons failing to seek help include limited accessibility to and affordability of hearing health care, particularly for unserved and underserved populations. Ideally, persons with hearing impairment may avoid negative consequences of hearing loss if they seek treatment early, when their losses are mild. This issue of Seminars inHearing focuses on the prevention and early diagnosis of and the intervention for slight-to-mild hearing loss in adults from a variety of perspectives. This issue also touches on concepts related to preclinical or hidden hearing losses (HHLs). Authors contributing to this issue report on current research conducted by faculty and students in theDepartment ofCommunicationSciences andDisorders and clinical outreach programs of the John W. Keys Speech andHearingCenter (AlliedHealth Clinics) at the University of Oklahoma Health Sciences Center in Oklahoma City, OK. The purpose of this preface is to provide readers with some background information that sets the context for the articles in this issue of Seminars in Hearing.
Editorial: The Least Cost Path From Landscape Genetics to Landscape Genomics: Challenges and Opportunities to Explore NGS Data in a Spatially Explicit Context

Citation: Cushman SA, Shirk AJ, Howe GT, Murphy MA, Dyer RJ and Joost S (2018) Editorial: The Least Cost Path From Landscape Genetics to Landscape Genomics: Challenges and Opportunities to Explore NGS Data in a Spatially Explicit Context. Front. Genet. 9:215. doi: 10.3389/fgene.2018. 00215 Editorial: The Least Cost Path From Landscape Genetics to Landscape Genomics: Challenges and Opportunities to Explore NGS Data in a Spatially Explicit Context
Forensic Odontology: Automatic Identification of Persons Comparing Antemortem and Postmortem Panoramic Radiographs Using Computer Vision

Abstract Purpose In forensic odontology the comparison between antemortem and postmortem panoramic radiographs (PRs) is a reliable method for person identification. The purpose of this study was to improve and automate identification of unknown people by comparison between antemortem and postmortem PR using computer vision. Materials and Methods The study includes 43 467 PRs from 24 545 patients (46 % females/54 % males). All PRs were filtered and evaluated with Matlab R2014b including the toolboxes image processing and computer vision system. The matching process used the SURF feature to find the corresponding points between two PRs (unknown person and database entry) out of the whole database. Results From 40 randomly selected persons, 34 persons (85 %) could be reliably identified by corresponding PR matching points between an already existing scan in the database and the most recent PR. The systematic matching yielded a maximum of 259 points for a successful identification between two different PRs of the same person and a maximum of 12 corresponding matching points for other non-identical persons in the database. Hence 12 matching points are the threshold for reliable assignment. Conclusion Operating with an automatic PR system and computer vision could be a successful and reliable tool for identification purposes. The applied method distinguishes itself by virtue of its fast and reliable identification of persons by PR. This Identification method is suitable even if dental characteristics were removed or added in the past. The system seems to be robust for large amounts of data. Key Points: Computer vision allows an automated antemortem and postmortem comparison of panoramic radiographs (PRs) for person identification. The present method is able to find identical matching partners among huge datasets (big data) in a short computing time. The identification method is suitable even if dental characteristics were removed or added. Citation Format Heinrich A, Güttler F, Wendt S et al. Forensic Odontology: Automatic Identification of Persons Comparing Antemortem and Postmortem Panoramic Radiographs Using Computer Vision. Fortschr Röntgenstr 2018; 190: 1152 – 1158
Roseomonas radiodurans sp. nov., a gamma-radiation-resistant bacterium isolated from gamma ray-irradiated soil.

A bacterial strain, designated 17Sr1-1T, was isolated from gamma ray-irradiated soil. Cells of this strain were Gram-stain-negative, strictly aerobic, motile and non-spore-forming rods. Growth occurred at 18-42 ˚C and pH 6.0-8.0, but no growth occurred at 2 % NaCl concentration. The major fatty acids of strain 17Sr1-1T were summed feature 8 (C18 : 1ω7c and/or C18 : 1ω6c), iso-C17 : 1ω5c and C16 : 0. The polar lipid profile contained diphosphatidylglycerol, glycolipid, phosphatidylcholine, phosphatidylethanolamine, phosphatidylglycerol and four unidentified lipids. The G+C content of the genomic DNA of 17Sr1-1T was 71.9 mol%. The 16S rRNA gene sequence analysis showed that strain 17Sr1-1T was phylogenetically related to Roseomonas pecuniae N75T and Roseomonas rosea 173-96T (96.6 and 96.3 % sequence similarity, respectively). The genotypic and phenotypic data showed that strain 17Sr1-1T could be distinguished from its phylogenetically related species, and that this strain represented a novel species within the genus Roseomonas, for which the name Roseomonas radiodurans sp. nov. (type strain 17Sr1-1T=KCTC 52899T=NBRC 112872T) is proposed as the first reported gamma ray-resistant Roseomonas species.
Determinant factors and choice intention for Chinese restaurant dining: a multivariate approach.

Abstract The purpose of this study is to identify important selection attributes for customers dining at Chinese restaurants in the state of Indiana, and the determinant and predicting factors in customers' intentions to return. A closed-ended questionnaire was used, and a systematic sampling approach was employed to survey a sample of customers in three Chinese restaurants in Indiana. The data were analyzed using factor and multiple regression analysis. A four-dimensional structure was established from 14 selection attributes. The results of the study indicated four dimensions that were significantly related to the likelihood of customers returning to the same restaurants, as follows: “Food and Environment,” “Service and Courtesy,” “Price and Value,” and “Location, and Advertising and Promotion. ”
PROMOpedi: A Web-Content Management-Based Encyclopedia of Software Property Models

The way software properties are defined, described, and measured, is different across different domains. When addressing these properties, several challenges commonly emerge, among which: synonymity, polysemy, paronymy, incomplete and inconsistent specification. In this paper we introduce PROMOpedia, an online encyclopedia, to tackle these challenges. PROMOpedia uses a web-content management system coupled with crowd-sourcing of scientific contents related to properties and their evaluation methods. The core concepts of PROMOpedia are built upon a property models ontology previously proposed by the authors, and is intended to target the needs of both researchers and practitioners. Website: http://www.mrtc. mdh.se/promopedia/
Model of jaw depression during feeding in Astatotilapia elegans (Teleostei: Cichlidae): Mechanisms for energy storage and triggering

Suction feeding in Astatotilapia elegans occurs by a series of rapid, coupled movements of various head parts. The lower jaw rotates with respect to the neurocranium through an angle of 62° in less than 15 ms. The power requirements for jaw depression are calculated from a mathematical model and may reach a peak of ±4 watt in a 12‐cm‐long specimen. Data from the literature on mechanical output of fish muscle suggest that a muscular volume equal to 44% of the volume of the fish (= 45 cm3) should be required, if it is premised that movement and muscle shortening are directly coupled. Therefore, we assumed that storage and release of strain energy must be considered. The work demands for depression equal 0.014 J. The amount of energy storable in only three pairs of head ligaments can be estimated between 0.008 J and 0.05 J. The use of strain energy implies initial blocking and subsequent triggering of the movement. The position of the hyalomandibular connection, dorsal to the mandibular‐suspensorial articulation, appears to be of crucial importance in balancing the forces of sternohyoideus and the body muscles. Triggering at the onset of jaw depression occurs by the contraction of the levator operculi. The line of action of the hyalomandibular connection is lowered beneath the jaw suspension, which raises the equilibrium of forces. Elastic recoil can occur thereafter.
The Performance of Turkish Manufacturing Firms in Stable And Unstable Economic Periods

The Performance of Turkish Manufacturing Firms in Stable And Unstable Economic Periods Generally, profitability is used to evaluate the performance of companies. Yet performance is a multidimensional concept, and therefore a single indicator is incapable of adequately defining its various aspects and providing a clear perspective on the critical mission of organizations. The measurement of the performance of a company is the evaluation of the level of attainment of the company's aims. Many factors can affect such aims. Companies must determine their own critical performance indicators and discover the relations between these indicators for optimal management and progress. The aim of this study is to discuss these business performance indicators, the relations between performance indicators and the factors that affect these indicators in the Turkish manufacturing industry, and to discuss how these relations vary during economically stable and unstable periods.
Aufbau von Markencommitment bei Mitarbeitern

Zusammenfassung: Organisationales Commitment (OC) ist innerhalb der Organisationsforschung als Prädiktor für erwünschte Einstellungen und Verhaltensweisen von Mitarbeitern anerkannt. In diesem Beitrag werden die Erkenntnisse zum OC auf das Konstrukt Marken-Commitment (MC) als zentrale Voraussetzung für markenorientierte Verhaltensweisen von Mitarbeitern übertragen sowie aktuelle Erkenntnisse aus der MC-Forschung integriert. Es wird eine Konzeptualisierung des MC sowie des Marken-Verhaltens (MarkenEnthusiasmus, Marken-Konformismus und Word-of-Mouth) vorgeschlagen. Zudem werden die Beziehungen zwischen OC und MC sowie den wesentlichen Antezedenten und Wirkungen des MC dargestellt und ein integriertes Modell beider Konstrukte vorgestellt.
From Host Heme To Iron: The Expanding Spectrum of Heme Degrading Enzymes Used by Pathogenic Bacteria

Iron is an essential nutrient for many bacteria. Since the metal is highly sequestered in host tissues, bound predominantly to heme, pathogenic bacteria often take advantage of heme uptake and degradation mechanisms to acquire iron during infection. The most common mechanism of releasing iron from heme is through oxidative degradation by heme oxygenases (HOs). In addition, an increasing number of proteins that belong to two distinct structural families have been implicated in aerobic heme catabolism. Finally, an enzyme that degrades heme anaerobically was recently uncovered, further expanding the mechanisms for bacterial heme degradation. In this analysis, we cover the spectrum and recent advances in heme degradation by infectious bacteria. We briefly explain heme oxidation by the two groups of recognized HOs to ground readers before focusing on two new types of proteins that are reported to be involved in utilization of heme iron. We discuss the structure and enzymatic function of proteins representing these groups, their biological context, and how they are regulated to provide a more complete look at their cellular role.