Miracle-dz/UniFAR-FTUs huggingface dataset:
Scheduled follow-up after a pediatric emergency department visit for asthma: a randomized trial.

OBJECTIVES Follow-up with a primary care provider (PCP) is recommended after an emergency department (ED) visit for asthma to assess clinical status and develop a management plan to improve future care. However, previous ED-based studies of urban children with asthma have reported low follow-up rates. The objective of this study was to determine whether scheduling an appointment at the time of an ED visit improves PCP follow-up for urban children. A secondary goal was to assess the effect of this intervention on short-term health outcomes and the use of recommended preventive controller medications. METHODS This randomized trial enrolled a convenience sample of children who were 2 to 18 years old and discharged after treatment for acute asthma in an urban children's hospital ED. Both intervention and control subjects were instructed to follow up with their PCP within 3 to 5 days. Study staff assisted intervention subjects to call their PCP from the ED and schedule an appointment. When follow-up could not be scheduled, assistance continued after ED discharge by telephone until an appointment date was confirmed. Study outcomes included PCP visits, asthma-related morbidity, and daily use of preventive medication 4 weeks after the ED visit. Outcomes were assessed by telephone interview and confirmed by PCP record review. RESULTS A total of 278 eligible subjects were enrolled over 8 months; intervention and control groups were similar by demographic variables and PCP type as well as by asthma history, symptoms, and previous medication use. Only 38% of subjects reported using a daily controller medication, although 70% described persistent asthma symptoms for which these are recommended. For the intervention group, follow-up appointments were successfully obtained during the ED visit for 24% of subjects; when unsuccessful, a median of 3 telephone calls (range: 1-14) were needed to confirm that an appointment had been scheduled. During the 4 weeks after the ED visit, intervention subjects were more likely than controls to follow up with their PCP (64% vs 46%; relative probability for follow-up: 1.4; 95% confidence interval: 1.1-1.7). Study groups did not differ in return ED visits, missed school or work, or the percentage reporting daily use of a controller medication (58% vs 54%) 4 weeks after the ED visit. The median time to the next PCP visit was shorter among intervention subjects (13 vs 54 days). CONCLUSIONS Scheduling an appointment after an ED visit increased the likelihood that urban children with asthma would follow up with a PCP. An appointment could not be obtained during the ED visit for most children. Other interventions are needed to improve linkage between ED and primary care for asthma and to improve the use of controller medications.
Initial Key Distribution for Industrial Wireless Sensor Networks

In any security design, the initial secret distribution for further key management solution is a major step. In industrial wireless sensor networks also, initial bootstrapping of the trust in the system is a major concern. The plant can be assumed to be a closed system, where only authenticated and trusted users are allowed to enter. However, wireless being the broadcast medium, wireless devices need to validate their identity to join the networks. So, there is a need for importing some initial secret key to the devices, so that they can be authenticated during the joining process. The standards for Industrial Wireless Sensor Networks (WirelessHART, ISA100.11a) also have left to the user the initial distribution of the key for joining during device provisioning. In this paper, the current industry practice and the pre-requisite of key distribution in industrial wireless sensor networks is discussed and an outline is presented for future research directions.
A deficit in contralesional object representation associated with attentional limitations after parietal damage

Stankiewicz, Hummel, and Cooper (1998) proposed that detailed coding of part–whole relations for objects is contingent on objects being attended. We report a neuropsychological test of this assertion. We examined the effects of left–right reflection on object matching in a group of patients with parietal damage and impaired attention to the contralesional side of space (Experiment 1). The patients were poor at matching objects subject to left–right reflection, relative to identical stimuli (Experiment 2). This was not due to a lack of sensitivity to information on the contralesional side. In a subsequent study, the patients were better at matching identical whole objects at fixation than when they just received half the object in their ipsilesional field (Experiment 3). However, unlike both nonlesioned controls and control patients with frontal lesions, the parietal patients were unaffected by altering the relative spatial locations of object features in their contralesional field (Experiment 4). The basic result, of poor performance with left–right-reflected items, was also replicated using a priming rather than an explicit matching procedure (Experiment 5). These results provide confirmation that visual attention, mediated by the posterior parietal cortex, is important for generating part–whole codes that facilitate the matching of mirror-reflected objects.
Building Blocks for Developing Spatial Skills: Evidence From a Large, Representative U.S. Sample

There is evidence suggesting that children’s play with spatial toys (e.g., puzzles and blocks) correlates with spatial development. Females play less with spatial toys than do males, which arguably accounts for males’ spatial advantages; children with high socioeconomic status (SES) also show an advantage, though SES-related differences in spatial play have been less studied than gender-related differences. Using a large, nationally representative sample from the standardization study of the Wechsler Preschool and Primary Scale of Intelligence–Fourth Edition, and controlling for other cognitive abilities, we observed a specific relation between parent-reported frequency of spatial play and Block Design scores that was invariant across gender and SES. Reported spatial play was higher for boys than for girls, but controlling for spatial play did not eliminate boys’ relative advantage on this subtest. SES groups did not differ in reported frequency of spatial play. Future research should consider quality as well as quantity of play, and should explore underlying mechanisms to evaluate causality.
Aplication`s Aspects Of Public Relations By Nonprofit Organizations. Case Study Albania

— The traditional public relations manager is usually responsible for maintaining and enhancing the reputation of the organization among key publics. While the principal focus of this effort is on support publics, it is quite clearly recognized that an organization's image has important effects on its own employees, its donors and volunteers, and its clients. The aim of paper is to define application`s aspects of public relations media and tools by nonprofit organizations in Albanian reality. Actually does used public relations media and tools, like written material, audiovisual material, organizational identity media, news, interviews and speeches, events, web sites by nonprofit organizations to attract donors? If, public relations media and tools are used, does exists a relation between public relation media and fundraising?
Functional Programming 1 Programming with Ornaments

Dependently typed programming advocates the use of various indexed versions of the same shape of data, but the formal relationship among these structurally similar datatypes usually needs to be established manually and tediously. Ornaments have been proposed as a formal mechanism to manage the relationships between such datatype variants. In this paper, we conduct a case study under an ornament framework; the case study concerns programming binomial heaps and their operations — including insertion and minimum extraction — by viewing them as lifted versions of binary numbers and numeric operations. We show how current dependently typed programming technology can lead to a clean treatment of the binomial heap constraints when implementing heap operations. We also identify some gaps between the current technology and an ideal dependently typed programming language that we would wish to have for our development.
Molecular characterization of Menangle virus, a novel paramyxovirus which infects pigs, fruit bats, and humans.

Menangle virus (MenV), isolated in August 1997 following an outbreak of reproductive disease in a piggery in New South Wales, is the second previously unclassified member of the family Paramyxoviridae to be identified in Australia since 1994. Similar to Hendra virus (HeV), MenV appears to be a virus of fruit bats (flying foxes) in the genus Pteropus. No serological cross-reactivity was detected between MenV and other known paramyxoviruses and to facilitate virus classification a cDNA subtraction method was used to obtain viral-specific cDNA from MenV-infected cells. Cloning and sequencing of the products enabled the entire sequences of the NP, P/V, M, F, and HN genes to be determined. Comparison of the nucleotide and deduced amino acid sequences for each gene with members of the family Paramyxoviridae, determination of the P gene mRNA editing strategy, and phylogenetic analyses confirmed that MenV is a new member of the genus Rubulavirus. However the deduced protein sequence of MenV HN exhibited only limited sequence homology when compared with attachment proteins of other paramyxoviruses. Key differences within the amino acid residues considered important determinants of neuraminidase activity suggest MenV HN is unlikely to possess the same degree of neuraminidase activity characteristic of other rubulavirus and respirovirus HN proteins.
Protective effect of grape seed extract in experimental menopausal syndrome.

UNLABELLED Grape seed extract (GSE) is a natural product obtained from Vitis vinifera seeds; it has been used as adjuvant therapy in wide range of pathological conditions. AIM In the present study, we investigated the ability of GSE to improve the mental status on ovariectomized rats. MATERIAL AND METHODS GSE (10 mg/kg/day, 60 days long) was administrated orally on ovariectomized adult female rats; then the animals were investigated in open field. Additionally, were measured the hematological parameters, the plasma biochemistry, and the oxidative stress markers. RESULTS AND DISCUSSION Treatment of GSE improved the loco motor activity in the open field, the number of crossings were almost twice in GSE treated rats (22.25 +/- 8.75) compared to placebo group (13.00 +/- 2.62) (p < 0.05). Lipid peroxides were reduced up to 51.57% (p < 0.05), while hematology and plasma biochemistry remained almost unchanged. CONCLUSION GSE improve the mental status and reduced the level of oxidative stress in rats subject to experimental ovariectomy.
[Activation of multiple tumor suppressor genes by MBD1 siRNA in pancreatic cancer cell line BxPC-3].

OBJECTIVE To observe the effect of MBD1-siRNA on the expressions of multiple tumor suppressor genes in pancreatic cancer cells, and to explore the role of MBD1 in carcinogenesis of pancreatic carcinoma. METHODS Two siRNA sequences targeting MBD1 were designed by software and cloned into the expression plasmid pGCsi-U6/Neo/GFP. DNA sequencing was used to confirm if the recombinant plasmid was constructed correctly. The constructed plasmid and the blank plasmid pGCsi-U6/Neo/GFP were stably transfected into human pancreatic cancer cells of the line BxPC-3. Nude mice underwent subcutaneous injection of the BxPC-3 cells transfected with the plasmid pGCsi-U6/Neo/GFP containing MBD1 or the blank plasmid pGCsi-U6/Neo/GFP to establish tumor models and were observed for 8 weeks. Mice without inoculation were used as controls. Eight weeks later the mice were killed with the tumors taken out. RT-PCR was used to detect the mRNA expression of MBD1 and the tumor suppressor genes related with DNA methylation, including CDH1, RASSF1A, TIMP3, P14ARF and Rb in transplanted tumors. RESULTS MBD1-siRNA recombinant plasmids were constructed successfully and stably transfected into the BxPC-3 cells. MBD1 was not detected in the tumors of the MBD1-siRNA group and could be found in the other 2 groups. However, the mRNA expression levels of CDH1, RASSF1A, TIMP3, P14ARF, and Rb of the MBD1-siRNA group (179.7 +/- 8.1, 155.6 +/- 10.0, 256.7 +/- 15.7, 199.0 +/- 7.9, 210.1 +/- 9.4) were all significantly higher than those of the other 2 groups (21.0 +/- 6.8, 22.0 +/- 2.7, 99.4 +/- 10.3, 86.0 +/- 5.4, 15.0 +/- 4.9, 11.4 +/- 6.0, 15.3 +/- 1.9, 110.7 +/- 14.1, 74.3 +/- 4.8, 17.4 +/- 7.8, all P < 0.05). CONCLUSION RNA interference decreases the expression of MBD1 in pancreatic cancer and up-regulate the transcription of tumor suppressor genes. MBD1 mediated transcriptional repression may play an important role in the development of pancreatic cancer.
The Association between the Nocturnal Sleep Gate and Nocturnal Onset of Urinary 6-Sulfatoxymelatonin

The present study investigated the relationship between the time of nocturnal onset of urinary 6-sulfatoxymelatonin (aMT6s) secretion, and the timing of the steepest increase in nocturnal sleepiness ("sleep gate"), as determined by an ultrashort sleep-wake cycle test (7 min sleep, 13 min wake). Twenty-nine men (mean age 23.8 ± 2.7 years) participated. The ultrashort sleep-wake paradigm started at 0700 hr after a night of sleep deprivation and continued for 24 hr until 0700 hr the next day. Electrophysiological recordings were carried out during the 7-min sleep trials, which were then scored conventionally for sleep stages. Urinary aMT6s was measured every 2 hr. The results showed that the timing of the sleep gate was significantly correlated with the onset of aMT6s secretion. These results are discussed in light of the possible role of melatonin in sleep-wake regulation.
Coupling Between Multipath Environments Through a Large Aperture

A key issue in measuring the shielding of buildings against wireless communications signals is presented. We use a mode-stirred reverberation chamber (RC) to emulate the EM coupling through windows or doors. This is achieved experimentally by leaving the RC door open. The room hosting the RC is identified as an external semi-reverberant space, and thus used to generate the stochastic field exciting the internal RC through the door opening. Two methods for the transmission parameter measurement and shielding effectiveness estimation are compared: the first one consists in moving receiving antenna within a volume, the second one makes use of a rotating stirrer. The comparison confirms the interchangeability of the two techniques provided a proper averaging factor is introduced. This argument supports a quasi-ergodic hypothesis in imperfect and semi-open reverberating environments. The measured aperture SE is compared to a theoretical value given by an ideal reverberating environment.
Image Composition Schemes for Sort-Last Polygon Rendering on 2D Mesh Multicomputers

In a sort-last polygon rendering system, the efficiency of image composition is very important for achieving fast rendering. In this paper, the implementation of a sort-last rendering system on a general purpose multicomputer system is described. A two-phase sort-last-full image composition scheme is described first, and then many variants of it are presented for 2D mesh message-passing multicomputers, such as the Intel Delta and Paragon. All the proposed schemes are analyzed and experimentally evaluated on Caltech's Intel Delta machine for our sort-last parallel polygon renderer. Experimental results show that sort-last-sparse strategies are better suited than sort-last-full schemes for software implementation on a general purpose multicomputer system. Further, interleaved composition regions perform better than coherent regions. In a large multicomputer system. Performance can be improved by carefully scheduling the tasks of rendering and communication. Using 512 processors to render our test scenes, the peak rendering rate achieved on a 282,144 triangle dataset is dose to 4.6 million triangles per second which is comparable to the speed of current state-of-the-art graphics workstations.
The Diagnostic and Prognostic Value of Serum Procalcitonin among Ventilator Associated Pneumonia Patients

Ventilator-associated pneumonia (VAP) is a complication in as many as 28% of patients who receive mechanical ventilation. Studies have consistently shown that a delay in diagnosis and treatment increases the mortality risk. The aim of this work was to clarify the role of the serum procalcitonin (PCT) in the diagnosis and the prognosis of ventilator associated pneumonia. Methods: Forty two VAP patients, 20 non VAP-ICU (on mechanical ventilation) admitted patients and 20 healthy control subjects of similar age and sex were included in the study. PCT levels in serum samples were measured in all subjects. Results: There was a highly statistically significant difference (p value < 0.001) between VAP patients on one side and non VAP-ICU patients and healthy control subjects on the other side regarding the mean values of PCT. Also, the mean values of PCT were statistically significantly higher (p < 0.001) among died VAP group than the survivor VAP group. There was a statistically positive correlation (p < 0.01) between mortality prediction scores (APACHE II (R = 0.449), CRIP (R = 0.403) and SOFA (R = 0.437)) and initial PCT serum levels. Conclusions: This study found that the increased PCT serum level is an important diagnostic tool for VAP and the PCT serum levels can predict the outcome of VAP patients. We recommend other larger studies to augment our findings.
Monoclonal antibody rat 401 recognizes schwann cells in mature and developing peripheral nerve

Monoclonal antibody Rat 401 recognizes subsets of cells in the developing central and peripheral nervous systems. Previous studies have shown that in the central nervous system (CNS) Rat 401 immunoreactivity diminishes sharply with cellular differentiation. Here we have examined the time course, cellular localization, and biochemical nature of the Rat 401 antigen in the rat peripheral nerve. In contrast to the CNS, in the periphery Rat 401 immunoreactivity is maintained into adulthood. Rat 401 staining is restricted to Schwann cells in mature peripheral nerve. Myelin‐related Schwann cells are intensely immunoreactive, whereas nonmyelin‐related Schwann cells are weakly immunoreactive. Unlike many Schwann cell markers, Rat 401 staining is maintained in cultured Schwann cells that lack axon contact. Biochemical analyses show that the antigen recognized by Rat 401 in the peripheral nerve is identical to that in embryonic CNS. The results demonstrate that the capacity for maintained Rat 401 immunoreactivity is restricted to Schwann cells as these cells are stained in adult animals as well as in embryos. In contrast, the same antigens are lost from the CNS at an early stage of development.
SISTEMA GEORREFERENCIADO DE REALIDAD AUMENTADA CON DISPOSITIVOS MÓVILES PARA LA FACULTAD TECNOLÓGICA DE LA UNIVERSIDAD DISTRITAL FRANCISCO JOSÉ DE CALDAS

Se describe el Sistema Georreferenciado de Realidad Aumentada, su funcionamiento general y los aspectos a tener en cuenta para la puesta en produccion. De igual forma se resumen los aspectos tecnicos de realidad aumentada, geolocalizacion y como su integracion sobre una plataforma movil apoyandose en el uso de tecnologias de la informacion y la comunicacion (TIC) puede conformar una solucion a las necesidades de determinado sector de la poblacion. En sintesis, se describe como los fabricantes de dispositivos moviles han dirigido esta tecnologia, el alcance que ha tenido este tipo de herramientas y los proyectos actuales de investigacion en Colombia, ademas de dar a conocer una herramienta desarrollada para la Facultad Tecnologica de la Universidad Distrital Francisco Jose de Caldas.
Feedback Linearization Control for Path Tracking of Articulated Dump Truck

The articulated dump truck is a widespread tansport vehicle for narrow rough terrain environment. To achieve the autonomous driving in the underground tunnel, this ariticle proporses a path following strategy of articulated vehicle based on feedback linearization algorithm. Fisrt of all, the articulated vehicle kinematics model, which reflects the relationship of the structure parameters and state variables, is established. Refering to the model, the nonlinear errors equation between real path and reference path, which are as the feedback from the path tracking process, is solved and linearized. After estimating the system controllable, according to the error equation, the path following controller with feedback linearization algorithm is designed through calaculating the parameters with the pole assignment. Finally, the hardware in the loop simulation on NI cRIO and PXI controller is lunched for verifying the control quality and real-time path tracking performance.
Extensive and long‐lasting changes of glial cells following transection of the poscommissural fornix in the adult rat

Injury to the adult brain results in the formation of a glial scar that involves both activated astroglia and microglia/macrophages. Although reactive gliosis has been linked to failure of axonal regeneration in the adult mammalian CNS, the spatio‐temporal pattern of the postlesion responses in morphology and distribution of the major cellular constituents of the gliosis has attracted little attention. In an attempt to define these relationships, we have undertaken a systematic study of astrocytic and microglial/macrophagic responses after stereotactic transection of the postcommissural fornix in rat.
Direct quantification of fetal cells in maternal blood by real‐time PCR

Fetal cells in maternal blood still present an enticing alternative for the development of a safe and efficacious non‐invasive method for prenatal diagnosis. However, most enrichment methods are very tedious and have failed to realise this long sought after goal. We developed a simple, robust TaqMan real‐time PCR assay to directly quantify male fetal cells in maternal blood using the multi‐copy DYS14, without the need for any additional enrichment procedure.
Long-Term Evolution of the Luteoviridae: Time Scale and Mode of Virus Speciation

ABSTRACT Despite their importance as agents of emerging disease, the time scale and evolutionary processes that shape the appearance of new viral species are largely unknown. To address these issues, we analyzed intra- and interspecific evolutionary processes in the Luteoviridae family of plant RNA viruses. Using the coat protein gene of 12 members of the family, we determined their phylogenetic relationships, rates of nucleotide substitution, times to common ancestry, and patterns of speciation. An associated multigene analysis enabled us to infer the nature of selection pressures and the genomic distribution of recombination events. Although rates of evolutionary change and selection pressures varied among genes and species and were lower in some overlapping gene regions, all fell within the range of those seen in animal RNA viruses. Recombination breakpoints were commonly observed at gene boundaries but less so within genes. Our molecular clock analysis suggested that the origin of the currently circulating Luteoviridae species occurred within the last 4 millennia, with intraspecific genetic diversity arising within the last few hundred years. Speciation within the Luteoviridae may therefore be associated with the expansion of agricultural systems. Finally, our phylogenetic analysis suggested that viral speciation events tended to occur within the same plant host species and country of origin, as expected if speciation is largely sympatric, rather than allopatric, in nature.