Miracle-dz/UniFAR-FTUs huggingface dataset:
Building IT Capability to Increase Organizational Performance: A Path-Oriented Process

Most studies on information technology (IT) capability have drawn their conceptualization from the tenets of resource-based view (RBV). Though path dependence is central to the concept of RBV, very few studies have examined the developmental paths of IT capabilities, which are typically treated as first-order constructs with their effects on firm performance investigated as direct causal links. This paper conceptualizes IT capability as the outcome of a pathspecific resource building process, driven by the e-business skills and knowledge of a firm’s IT human resources, which we refer to as e-business centric IT expertise. We posit that through the use of appropriate IT infrastructure, and the development of back-end integration and front-end functionalities, e-business centric IT expertise could be harnessed to provide the right information to the right customers at the right time, giving rise to a firm-specific IT capability. We further contend that IT capability is a source of competitive advantage, offering inimitable differentiation in market responsive agility, which is a key to securing sales in an increasingly customer-centric market. We operationalize these conceptualizations as a structural equation model (SEM) and tested 12 hypothesized relationships using data drawn from a survey of 310 fast-growth smallto-medium sized companies in Australia. The test results uphold 10 of the 12 formulated hypotheses, supporting our conceptualization that IT capability building is a path-specific process. To affirm our contention that IT capability is developed from the interacting effects of a suite of IT resources, and not the sum of the disjointed effects of individual resources, we also formulated and tested an alternative model that links individual IT resources directly to market responsive agility. Combined with a series of mediation tests, our SEM exercises confirm that IT resources interact in a specific way to give rise to IT capability to enhance market responsive agility and achieve sales performance. We discuss the implications of these findings in the context
Moringa (Moringa oleifera) Leaves' Extract and Linseed (Linum usitatissimum) Oil Ameliorate Piroxicam Induced Gastric Ulcers in Male Rats

Gastric ulcer is a standout amongst the most significant gastrointestinal disorders affecting human worldwide. An extraordinary interest should be given to find natural medications to treat this disease. Plant extracts are more favored because of their wide safety margins and less or no adverse health impacts. The present study was conducted to assess the antiulcer activities of hydroethanolic extract of moringa leaves (500mg Kg BW) and linseed oil (0.3mL/ Kg BW) on piroxicam (30 mg Kg BW) induced gastric ulcers in Wister albino rats. Forty five adult male albino rats were allocated into five equal (9 each) groups designated as negative control, piroxicam, ranitidine, moringa and linseed oil groups. The results revealed that administration of piroxicam in a single oral dose induced gastric ulcers in rats, decrease in body weights (187.50±10.51g) and increase in gastric juice (1.64±0.24mL) with altered hematological, biochemical and histological findings. Meanwhile, oral administration of ranitidine, Moringa oleifera and linseed oil amelioratedthe ulcerogenic effect of piroxicam with curative ratios of 100, 97.5 and 100%, respectively. From the previous findings we concluded that hydroethanolic extract of moringa leaves and linseed oil were effective treatments of piroxicam induced gastric ulcer in rats. Antiulcerogenic effect of moringa and linseed oil may be attributed to their anti-inflammatory and antioxidant properties.
Adapting Neural Machine Translation for English-Vietnamese using Google Translate system for Back-translation

In this paper, we propose a method to better leveraging monolingual data by exploiting the advantages of GNMT system. Our method for adapting a general neural machine translation system to a specific domain, by exploiting Back-translation technique using targetside monolingual data. This solution requires no changes to the model architecture from a standard NMT system. Experiment results show that our method can improve translation quality, results significantly outperforming strong baseline systems, our method improves translation quality in legal domain up to 13.65 BLEU points over the baseline system for English-Vietnamese pair language.
Application of Surface Electromyography in the Estimate of Neural-muscle Function (review)

The surface electromyography (sEMG) is the noninvasive method which can record and measure the changes of local muscle activities. The sEMG's amplitude and frequence signal will change with muscular movement. sEMG application in present study on muscle fatigue is a reliable predictor of muscle functional level. The researches on the sEMG signals changes of limb muscles of hemiplegic patients will take a important role in providing scientific evidence for the neural rehabilitation training after stroke.
Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study

Background Stress, anxiety and impeded sleep are a frequent feature of life in modern societies. Across socio-economic strata, stress, anxiety and ineffective sleep detract from healthful living and serve as precursors of various ailments. The use of herbs to offset these antecedents and outcomes has greatly increased in recent years. Ashwagandha, an adaptogenic Ayurvedic herb, has been often used to combat and reduce stress and thereby enhance general wellbeing. While there have been other studies documenting the use of Ashwagandha for stress resistance, this is the first study to use a high-concentration root extract while also varying the dosage substantially. Therefore, this is the first study to offer insight into dose-response of a high concentration root extract. Material and methods In this eight-week, prospective, randomized, double-blind, placebo-controlled study, the stress-relieving effect of Ashwagandha root extract was investigated in stressed healthy adults. Sixty male and female participants with a baseline perceived stress scale (PSS) score >20 were randomized to receive capsules of Ashwagandha extract 125 mg, Ashwagandha extract 300 mg or identical placebo twice daily for eight weeks in a 1:1:1 ratio. Stress was assessed using PSS at baseline, four weeks and eight weeks. Anxiety was assessed using the Hamilton-Anxiety (HAM-A) scale and serum cortisol was measured at baseline and at eight weeks. Sleep quality was assessed using a seven-point sleep scale. A repeat measures ANOVA (general linear model) was used for assessment of treatment effect at different time periods. Post-hoc Dunnett’s test was used for comparison of two treatments with placebo. Results Two participants (one each in 250 mg/day Ashwagandha and placebo) were lost to follow-up and 58 participants completed the study. A significant reduction in PSS scores was observed with Ashwagandha 250 mg/day (P < 0.05) and 600 mg/day (P < 0.001). Serum cortisol levels reduced with both Ashwagandha 250 mg/day (P < 0.05) and Ashwagandha 600 mg/day (P < 0.0001). Compared to the placebo group participants, the participants receiving Ashwagandha had significant improvement in sleep quality. Conclusion Ashwagandha root aqueous extract was beneficial in reducing stress and anxiety.
Accurate alignment-free inference of microbial phylogenies

Classifying, clustering or building a phylogeny on a set of genomes without the expensive computation of sequence alignment involves calculating pairwise distances by an appropriate metric. One such metric is the normalized compression distance (NCD), an approximation of the true information distance between two objects. Despite NCD’s universal applicability, it has seen few applications in bioinformatics, with no existing tools applying NCD to wholegenome datasets to the best of our knowledge. We introduce Sequence Non-Alignment Compression and Comparison (snacc), a pipeline specifically tailored for computing pairwise distances between genomic sequences. snacc employs the NCD with a variety of compression algorithms, alongside an integer linear programming approach for selecting a sequence’s reverse complement. We investigate the use of snacc with 5 common compression algorithms, and apply it to several bacterial and viral datasets with varying properties. Our results show that snacc achieves comparable accuracy relative to other metrics, demonstrating a large improvement over previous NCD implementations, and can be successfully used to reconstruct microbial phylogenies. In addition, snacc is flexible enough to incorporate almost any compression algorithm in a simple manner. snacc is an open-source tool and is available at https://github.com/ SweetiePi/snacc/.
Protective Effect of Cerium Oxide Nanoparticles on Oxaliplatin induced Neurotoxicity in Adult Male Albino Rats

Oxaliplatin is a chemotherapeutic agent used for treatment of colorectal cancer. Peripheral neuropathy is a dose limiting toxicity which may persist even after its termination. Oxidative stress may be a direct cause of this neurotoxicity. Cerium oxide nanoparticles (CONPs) are promising antioxidants for applications in medicine. The present work was designed to study the protective effect of CONPs on neurotoxicity induced by oxaliplatin in adult male albino rats. One hundred and twenty male adult albino rats were divided into 4 groups: Control group, CONPs group (60mg/kg, 5 times/week), Oxaliplatin group (4mg/kg, twice/week) and Oxaliplatin&CONPs group, for 8 weeks. After 4 & 8 weeks, 10 rats from each group were used to measure myelin protein zero (MPZ), malondialdhyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx) and reduced glutathione (GSH) in the left sciatic nerves. The right sciatic nerves and lumbar spinal cord were used for histopathological study. Oxaliplatin decreased MPZ and induced demyelination and degeneration of sciatic nerve fibers. Also, it increased MDA levels. SOD and GPx activity were increased then decreased. GSH levels were decreased. In the lumbar spinal cord sections, abnormal morphology was seen. CONPs administration with oxaliplatin increased MPZ and returned normal morphology of sciatic nerve fibers. They decreased MDA levels. SOD was increased after 8 weeks, GPx and GSH not changed. In the lumbar spinal cord sections normal morphology was seen with some hydropic degeneration. Oxaliplatin treatment induced hypomyelination in sciatic nerves. CONPs have neuroprotective effect.
Poole–Frenkel Emission Saturation and Its Effects on Time-to-Failure in Ta-Ta2O5-MnO2 Capacitors

I-V characterization of Ta-Ta2O5-MnO2 capacitors was investigated at different temperatures, and Poole–Frenkel (PF) emission saturation was experimentally observed. Under the saturation voltage, the I-V curves at different temperature converged, and the temperature dependency was vanished. Above the saturation voltage, the leakage current was decreasing as the temperature increased. In order to evaluate the effects of saturation voltages (VS) on time-to-failure (TTF) of the capacitors, VS were first determined at +2°C and +25°C, then voltage accelerating tests were conducted at 85°C under 1.6 times of rated voltage. e distribution of VS and TTF of the samples were plotted and compared. It was shown that samples with lower saturation voltage failed earlier in the distribution of time-dependent dielectric breakdown. Comparing conventional methods for evaluating the quality of tantalum capacitors by measuring the leakage current at elevated temperature, the nondestructive measurement of saturation voltage at +2°C and +25°C may provide a novel and practicing approach tool to screening out capacitors with defected Ta2O5 layers.
Conceptual Metaphors and Image Schemas in a News Entitled “Katy Perry and Taylor Swift Officially Bury the Hatchet”: A Cognitive Semantic Study

Metaphors in cognitive semantics play important roles as phenomena to be understood. Understanding them require elaboration of both semantics and cognition. A news entitled “Katy Perry and Taylor Swift officially bury the hatchet” is an object that is worth studying in the light of cognitive semantics, especially the metaphors employed. The metaphors are compiled and classified into their types. From the metaphors obtained, the image schemas employed to understand the metaphors are explicated. The discussion on it is attached to the explanation of the metaphorical expressions found in the news. The result shows that there are 11 (eleven) metaphorical expressions with their own classifications noted and different image schemas that background the meaning-making process of the metaphors. Finally, by relying upon the results of the analysis, it can be concluded that there are ways, signified by the implementation of image schemas, to understand metaphors.
Compound Lactobacillus sp. Administration Ameliorates Stress and Body Growth Through Gut Microbiota Optimization on Piglet Model

The composition of bacteria in the gastrointestinal tract of piglets is easily affected by environmental changes, particularly during the weaning period. Compound strains of Lactobacillus reuteri and Lactobacillus salivarius were supplemented to piglets during pre- and post-weaning to determine their effects in improving the growth performance and ameliorating the diarrhea rate and stress caused by antioxidation in piglets. A larger number of L. reuteri and L. salivarius colonized the distal segment of the ileum and the total numbers of Lactobacillus spp. and Bifidobacterium were higher in the ileal mucous membrane and cecal lumen with probiotics supplementation. The numbers of antioxidative and immune molecules were increased in the plasma following compound bacteria (CL) supplementation, whereas cortisol and endotoxin levels were lower and growth hormone and insulin-like growth factor 1 were higher. Spearman’s and KEGG analysis of the bacterial operational taxonomic unit and antioxidative and immune indices and metabolic genes indicated that the body growth modulation by CL supplementation could be attributed to optimization of the intestinal bacterial composition. Collectively, these results suggest that supplementation with CL could reduce stress and improve the growth performance of piglets during weaning by optimizing the intestinal bacterial composition.
Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese Population

Background: Oily fish and their extracted oils may be a source of polychlorinated biphenyls (PCBs) which can induce toxic effects on the consumers. The main aim of this survey was estimation of PCBs intake through fish oil-derived dietary supplements and prescription drugs in the Japanese population. Methods: PCBs levels were determined in 20 fish oil-derived dietary supplements and 6 oil-derived prescription drugs from the Japanese market using Gas Chromatography-Mass Spectrometry. Then, the daily exposure to PCBs was estimated. Data were statistically analyzed using JMP software suite. Results: Totally, 17 of the 26 fish oil-derived products were contaminated with PCBs. The median PCB concentrations in the total set of fish oil-derived products was 2.2 ng/g oil wt. with a range of <MDL-720 ng/g oil wt. The average total daily intake of PCBs was estimated to be ranged from 770 to 2800 ng/day in the Japanese population. Conclusion: PCBs intakes through fish oil-derived dietary supplements and prescription drugs in the Japanese adults were much lower than tolerable daily intake
Bace1 activity impairs neuronal glucose metabolism: rescue by beta-hydroxybutyrate and lipoic acid

20 Glucose hypometabolism and impaired mitochondrial function in neurons have been 21 suggested to play early and perhaps causative roles in Alzheimer’s disease (AD) 22 pathogenesis. Activity of the aspartic acid protease, beta-site amyloid precursor protein 23 (APP) cleaving enzyme 1 (BACE1), responsible for beta amyloid peptide generation, has 24 recently been demonstrated to modify glucose metabolism. We therefore examined, using a 25 human neuroblastoma (SH-SY5Y) cell line, whether increased BACE1 activity is responsible 26 for a reduction in cellular glucose metabolism. Overexpression of active BACE1, but not a 27 protease-dead mutant BACE1, protein in SH-SY5Y cells reduced glucose oxidation and the 28 basal oxygen consumption rate, which was associated with a compensatory increase in 29 glycolysis. Increased BACE1 activity had no effect on the mitochondrial electron transfer 30 process but was found to diminish substrate delivery to the mitochondria by inhibition of key 31 mitochondrial decarboxylation reaction enzymes. This BACE1 activity-dependent deficit in 32 glucose oxidation was alleviated by the presence of beta hydroxybutyrate or α-lipoic acid. 33 Consequently our data indicate that raised cellular BACE1 activity drives reduced glucose 34 oxidation in a human neuronal cell line through impairments in the activity of specific 35 tricarboxylic acid cycle enzymes. Because this bioenergetic deficit is recoverable by 36 neutraceutical compounds we suggest that such agents, perhaps in conjunction with BACE1 37 I re view
Knowledge, Attitude, and Practices Regarding Nutrition for Patients With Chemotherapy

Background; good nutrition & eating are important especially during treatment which might enhance the effectiveness of tumor treatments & which can lead to better outcomes for cancer treatment. The aim: assess Knowledge, attitude, and practices regarding nutrition for patients with chemotherapy. Samples: A convenience sample of 60 adult patients, the age between 20 - 60 years both sex, evidence of cancer and recent receiving all types of chemotherapy. Three tools were utilized for data collection were Tool (I) Structured interviewing Questionnaire Tool (II) Nutritional Status Assessment and Tool (III) Chemotherapy Knowledge, Attitude and practice (KAP) Questionnaire. Results: More than two thirds of samples were unsatisfied level of knowledge (60%). The majority of studied sample were positive attitude and poor practice (95%, 86.6%) respectively. Conclusions: About two third of the patient were unsatisfactory information. The majority of the patient were positive attitude and had poor practice respectively. Recommendations: Give advices & guidelines for patients to minimize malnutrition complications & improve clinical outcomes, formulate nutritional assessment form or sheet to be suitable for Egyptian patients undergoing chemotherapy in the hospitals.
Resveratrol Supplement Could Reverse the Effect of Resistance Training on Muscular eMHC and PAX7 in BALB/C Mice Bearing CT-26 Tumor

Introduction: Although resistance training and resveratrol is recommended as a stimulant for muscle regeneration in healthy subjects their effects on cancer-related cachexia indices are unclear. This study aimed to investigate the effect of a course of resistance training with resveratrol supplement on PAX-7 and eMHC in Gastrocnemius muscle tissue of mice bearing colon cancer induced cachexia. Methods: This was an experimental study conducted on 20 six-week-old BALB/c mice implanted with CT-26 tumor. The mice were randomly divided into four groups: resistance training, resveratrol, resveratrol with resistance training, and control. The resistance training group performed 6 weeks of progressive resistance training, the resveratrol group received 100 mg/kg resveratrol per day. 48 hours after the last experimental session, the mice were sacrificed and PAX-7 and eMHC protein levels were measured using ELISA test through specimen taken from gastrocnemius muscles. Statistical test of one way ANOVA was used for data analysis. Results: PAX-7 level was significantly lower in resveratrol with resistance training group compared to control (P=0.009), resveratrol (P=0.005), and resistance training groups (P=0.002). eMHC was significantly lower in the resistance training group compared to the control (P=0.08), resistance training, and resveratrol groups (P=0.002). Conclusion: Resistance training was not an appropriate intervention for treating reduced muscular regeneration due to cachexia. However, regarding reducing effect of resveratrol supplementation with resistance training on PAX-7 level, it may be recommended to improve muscular regeneration.
Gratitude Speech Act in Instagram: The Emergence of a Particular Genre of Language?

The present study investigated the speech act of gratitude in the context of Instagram as one of the most popular social networks. It sought to consider English and Persian users’ utilization of gratitude strategies in terms of employment of politeness strategies, intensifiers, interjections, and gender difference. To this end, 200 English Instagram posts along with 200 Persian Instagram posts were investigated. Contrary to previous findings that indicated different performances by English and Persian language speakers in real-life situations, the results of this study, after performing chi-square tests, suggested no significant difference between English and Persian users in terms of their utilization of politeness strategies, intensifiers, and interjections. Regarding gender difference, which addressed the use of both gratitude and politeness strategies for each language, for both nationalities, no significant difference was observed between female and male users within the context of Instagram. The finding may signify the emergence of a new genre of language belonging to social networks in general and Instagram in particular.
Explaining elite perceptions of legitimacy in global governance

Elites are central in creating, operating, defending and contesting international organisations (IOs), but little research is available about their attitudes toward these bodies. To address this gap, this article offers the first systematic and comparative analysis of elite perceptions of IO legitimacy. Building on a unique multi-country and multi-sector survey of 860 elites undertaken in 2017–19, we map and explain elite legitimacy beliefs toward three key IOs in different issue-areas: the International Monetary Fund (IMF), the United Nations Framework Convention on Climate Change (UNFCCC) and the United Nations Security Council (UNSC). Integrating public opinion research and international relations theory, the article advances an explanation of elites’ legitimacy beliefs that emphasises their satisfaction with the institutional qualities of IOs. We contrast this argument with three common alternative explanations, which respectively highlight utilitarian calculation, global orientation and domestic cues. The analyses show that elites’ satisfaction with institutional qualities of IOs is most consistently related to legitimacy beliefs: when elites are more satisfied with democracy, effectiveness and fairness in IOs, they also regard these IOs as more legitimate. These findings suggest that the prevailing debate between utilitarian calculation, global orientation and domestic cues approaches neglects the importance of institutional satisfaction as an explanation of attitudes toward IOs.