Miracle-dz/UniFAR-FTUs huggingface dataset:
A retrospective comparative study of traction therapy vs. no traction following tunica albuginea plication or partial excision and grafting for Peyronie's disease: measured lengths and patient perceptions.

INTRODUCTION Loss of penile length is a recognized and common consequence of Peyronie's disease (PD). Traction therapy (TT+) has been reported to decrease post-op length loss as well as increase stretched penile length (SPL) prior to surgery. AIM The aim of this study was to study patient outcomes with penile length change and patient satisfaction after surgery following tunica albuginea plication (TAP) and partial plaque excision and grafting (PEG) with or without postoperative TT. METHODS Retrospective analysis was performed from our cohort of Peyronie's reconstructive surgery between 2007 and 2010. SPL was measured dorsally from pubis to corona and recorded at the initial office visit and then compared to most recent postoperative visit. Patients were then stratified by procedure and whether TT was used (TT+ and TT-; TAP N = 52 [27 TT+ and 25 TT-] and PEG N = 59 [36 TT+ and 23 TT-). Traction therapy was initiated for >2 hours a day for 3 months typically starting 3-4 weeks postoperatively. A non-validated mailed questionnaire assessed patient perceptions. RESULTS Mean length change seen in TAP (TT+) was 0.85 cm (0.25-1.75) vs. -0.53 cm (-1.75 to 0.5) in TAP (TT-) (P < 0.001). The mean length change seen in PEG (TT+) was 1.48 cm (0-6) vs. PEG (TT-) 0.24 cm (-1 to 2.5 cm) (P < 0.001). Sixty-one percent of surveys were returned; 85% lost length prior to the initial office evaluation, with an average of -2.5 cm lost. Importantly, in those who used traction, there was no perceived length loss, 58% reported a mean erect length gain of 1.1 cm. However, only 54% of all patients were satisfied with their current erect length. CONCLUSIONS Loss of length in men with PD remains a serious concern. It appears that postoperative TT can result in length preservation, and in many, a measured and perceived length gain following correction of the curvature.
Aspergillus fumigatus and Aspergillosis

SUMMARY Aspergillus fumigatus is one of the most ubiquitous of the airborne saprophytic fungi. Humans and animals constantly inhale numerous conidia of this fungus. The conidia are normally eliminated in the immunocompetent host by innate immune mechanisms, and aspergilloma and allergic bronchopulmonary aspergillosis, uncommon clinical syndromes, are the only infections observed in such hosts. Thus, A. fumigatus was considered for years to be a weak pathogen. With increases in the number of immunosuppressed patients, however, there has been a dramatic increase in severe and usually fatal invasive aspergillosis, now the most common mold infection worldwide. In this review, the focus is on the biology of A. fumigatus and the diseases it causes. Included are discussions of (i) genomic and molecular characterization of the organism, (ii) clinical and laboratory methods available for the diagnosis of aspergillosis in immunocompetent and immunocompromised hosts, (iii) identification of host and fungal factors that play a role in the establishment of the fungus in vivo, and (iv) problems associated with antifungal therapy.
First-Trimester Fetal Growth Restriction Risk Factors and Outcomes Associated With

Supplementary material http://jama.ama-assn.org/cgi/content/full/303/6/527/DC1 eSupplement Correction Contact me if this article is corrected. Citations Contact me when this article is cited. This article has been cited 3 times. Topic collections Contact me when new articles are published in these topic areas. Prognosis/ Outcomes Pediatrics; Child Development; Women's Health; Pregnancy and Breast Feeding;
Processing Conjunctive Predicates and Queries

Several aspects of relational database systems require the processing of predicates. For example, predicates can be tested for satisfiability (as in processing predicate locks), and predicates occurring in queries may be preprocessed in order to reduce the number of database operations when the query is answered. Here we study predicates consisting of conjunctions of comparisons. First, we consider predicates that are conjunctions of =, , and >= comparisons, where a variable can be compared with a constant or with another variable, possibly offset by a constant. Efficient algorithms are given for satisfiability, equivalence, and minimizing the number of comparisons in a predicate. Second, we show that when unequal comparisons between variables are allowed, satisfiability, equivalence, and minimization are NP-hard. Most approximation problems corresponding to minimization are also NP-hard. The preceding efficient algorithms show that the unequal comparison operation is the sole cause of this complexity.
STREAM WITH FRAGMENT LABELING

The portable/hand-held devices deployed in mobile computing environment are mostly limited in memory. To make it possible for them to locally process queries over a large volume of XML data, the data needs to be streamed in fragments of manageable size and the queries need to be processed over the stream with as little memory as possible. In this paper, we report a considerable improvement of the state-of-the-art techniques of query processing over XML fragment stream in memory efficiency. We use XML fragment labeling (XFL) as a method of representing XML fragmentation, and show that XFL is much more effective than the popular hole-filler (HF) model employed in the state-of-the-art in reducing the amount of memory required for query processing. The state-of-the-art with the HF model requires more memory as the stream size increases. With XFL, we overcome this fundamental limitation, proposing the techniques to make query processing scalable in the sense that memory requirement is not affected by the size of the stream as long as the stream is bounded. The improvement is verified through implementation and a detailed set of experiments.
VORTEX CREEP AGAINST TOROIDAL FLUX LINES, CRUSTAL ENTRAINMENT, AND PULSAR GLITCHES

A region of toroidally oriented quantized flux lines must exist in the proton superconductor in the core of the neutron star. This region will be a site of vortex pinning and creep. Entrainment of the neutron superfluid with the crustal lattice leads to a requirement of superfluid moment of inertia associated with vortex creep in excess of the available crustal moment of inertia. This will bring about constraints on the equation of state. The toroidal flux region provides the moment of inertia necessary to complement the crust superfluid with postglitch relaxation behavior fitting the observations.
An Examination of Cybersecurity Knowledge Transfer: Teaching, Research, and Website Security at U.S. Colleges and Universities

This work seeks to answer the question: Does faculty cybersecurity knowledge gained from teaching and research transfer to other IT units in the university? Specifically, do colleges and universities that excel in cybersecurity teaching and research have more secure websites? This work explores a unique setting where the knowledge of the source and recipient are both directly related and observable without outside intervention. Our study employed data from 591 U.S. colleges and universities, the National Centers of Academic Excellence (CAE) program, accepted paper data from the ACM Conference on Computer and Communications Security (CCS) and the IEEE Symposium on Security and Privacy (SSP), as well as the results from the SSL Labs Server Test. Our data suggest that universities with cybersecurity research excellence receive higher grades for website security. However, university website security is not significantly associated with cybersecurity teaching excellence, institution size or tuition costs.
Alergia a las proteínas de la leche. ¿Puede considerarse la leche de cabra hipoalergénica respecto a la de vaca?

La leche de las distintas especies de rumiantes, bien directamente o en forma de productos derivados, constituye un alimento de singular importancia para el ser humano durante toda su vida. Este alimento puede considerarse fuente de macronutrientes y micronutrientes, conteniendo ademas, un cierto numero de compuestos activos que juegan un papel tanto nutritivo como de proteccion. Ya sea para su consumo directo o en forma de productos transformados, la leche de vaca es la mas empleada en el mundo occidental, en razon de su mayor disponibilidad. Junto a esto, uno de los principales problemas asociados a su consumo, sobre todo durante los primeros estadios de vida, reside en la reaccion alergica que a sus proteinas, con cierta frecuencia se produce, problema que se intenta solucionar sustituyendo en los alimentos lacteos infantiles, la proteina vacuna por distintos hidrolizados de la misma o, incluso, por proteinas de origen vegetal. En relacion con esto, desde hace tiempo se conoce como el problema descrito, queda a veces solucionado sustituyendo simplemente, la leche de vaca por la de cabra, hecho que viene adjudicando a esta ultima, un caracter hipoalergenico frente a la de vaca, aspecto aun hoy dia en discusion.
Analysis and design of a LCC resonant current-source power supply for PFU charging applications

In this paper, a LCC series-parallel resonant converter is designed for the electromagnetic launch system, in which, the power supply charges for the energy-storage capacitor in the Pulse Forming Unit. At first, the operational principles of the LCC resonant topology operating in Discontinuous-Current-Mode are analized and the detailed expressions describing the resonant topology are derived. In order to attain the Zero-Current-Switch characteristics in DCM, traditional pulse frequency modulation always restricts the up-band of switches operating frequency, this results in a decrease in output averaged current with the increase of PFU capacitor voltage. This affects the PFU charging efficiency greatly. While, it is an efficient way to solve this problem using the modulation of critical-DCM to extend frequency up-band, which can improve the duty ratio of the output current, ensure the charging efficiency. In this paper, an equivalent simplified linear function is developed to fit with the critical-DCM frequency one, so critical-frequency curve can be tracked online by using Digital-Signal-Processor. The duty ratio of the output current under critical frequency is improved greatly in contrast with traditional PFM. Moreover, in order to obtain a constant current output, a charging current-fed digital PID control scheme in DSP is designed for overcoming the input voltage disturbance and load disturbance. At last, the pictures of energy-storage capacitor charging supply and experiment figures are presented. Simulation and experimental results verify the analysis with good agreement. The designed power supplies realize ZCS soft-switching in the whole operating process, and at the same time, a constant output of charging current is obtained. The expected performance of 0-6kV charging voltage and 1A output current are achieved. The power supply group can be managed by the upper computer through CAN bus.
Producer Perceptions, Economic Value and Incentives for Promotion of Potential Geographical Indications in Kenya

Sustained growth in Kenya’s agricultural sector is the main driver of economic development hence the focus of the sector as one of the key economic pillars in the Vision 2030 and the Agricultural Sector Development Strategies. Diversification through protecting products presented in the market with geographical indications (GIs) is an opportunity for increasing rural incomes. A scoping study was conducted as a first step towards identifying Kenyan origin products that have potential to be registered as GIs. Before identifying the products, a selection criterion was developed from literature and interaction with key informants. Potential products and their production regions were then identified based on the perceived 4 Paper published as: “Maina FW and H Egelyng. 2018. Characterisation of unique agri-food products for geographical indications protection potential in Kenya and scope for up-scaling. African Journal of Intellectual Property, Volume 2 (2) (June 2018): 164 – 191”. 38 uniqueness from similar products from different production regions. Eleven products were identified, namely tea, coffee, apple and ngowe mangoes, oranges, avocadoes, pyrethrum, Koriema goats, tilapia from Busia, Baobab and wild silk. Relevant stakeholders were identified with help from key informants in the different sub-sectors. The informants were interviewed either individually or through focus group discussion comprising of producers and few traders. Traders in the urban markets were also interviewed. Each product was then subjected to the selection criteria developed. From the criteria, tea, Koriema goats, coffee, tilapia fish and Makueni apple mangoes were ranked highest. The criteria provide a combination of factors to consider, in establishing the potential success of GI protection. The analysis points to the relevance of future research on the quality of origin products and institutional regimes for geographical indications in Kenya.
‘The Ghost Pushes You Down’: Sleep Paralysis-Type Panic Attacks in a Khmer Refugee Population

Among a psychiatric population of Cambodian refugees (N = 100), 42% had current - i.e. at least once in the last year - sleep paralysis (SP). Of those experiencing SP, 91% (38/42) had visual hallucinations of an approaching being, and 100% (42/42) had panic attacks. Among patients with post-traumatic stress disorder (PTSD; n = 45), 67% (30/45) had SP, whereas among those without PTSD, only 22.4% (11/45) had SP (χ2 = 20.4, p < .001). Of the patients with PTSD, 60% (27/45) had monthly episodes of SP. The Cambodian panic response to SP seems to be greatly heightened by elaborate cultural ideas - with SP generating concerns about physical status, ‘good luck’ status,‘bad luck’ status, sorcery assault, and ghost assault - and by trauma associations to the figure seen in SP. Case vignettes illustrate cultural beliefs about, and trauma resonances of, SP. A model to explain the high rate of SP in this population is presented. SP is a core aspect of the Cambodian refugees response to trauma; when assessing Cambodian refugees, and traumatized refugees in general, clinicians should assess for its presence.
The Pharmacokinetics and Safety of ABT-751, a Novel, Orally Bioavailable Sulfonamide Antimitotic Agent: Results of a Phase 1 Study

Purpose: Microtubules play a critical role in many cellular functions, including cell division and mitosis. ABT-751 is a novel sulfonamide antimitotic that binds to the colchicine site on β-tubulin that leads to a block in the cell cycle at the G2M phase, resulting in cellular apoptosis. ABT-751 was investigated in this phase 1 trial designed to assess its maximum tolerated dose (MTD), dose-limiting toxicity (DLT), tolerability, and pharmacokinetics. Experimental Design: ABT-751 was administered on a daily (q.d.) or twice daily (b.i.d.) oral schedule for 7 days every 3 weeks to 39 patients with refractory solid tumors. Toxicity was monitored weekly. Plasma and urine ABT-751 and metabolite pharmacokinetics were determined. Results: The MTD for the q.d. schedule was 250 mg/d. DLTs during cycle 1 were abdominal pain, constipation, and fatigue. The MTD on the b.i. d. schedule was 150 mg. Cycle 1 of therapy with the 175 mg b.i. d. schedule was tolerated without DLT. However, six of seven patients reported grade 3 toxicity (ileus, constipation, abdominal pain, or fatigue), which occurred in cycle 2 or 3. ABT-751 was absorbed after oral administration with an overall mean Tmax of about 2 hours. The pharmacokinetics of ABT-751 were dose-proportional and time-independent. There was minimal accumulation of ABT-751 after multiple q.d. and b.i. d. doses. Efficacious concentrations, as determined from preclinical models (0.5-1.5 μg/mL), were achieved in all subjects. ABT-751 metabolism occurred primarily by glucuronidation and sulfation. No complete or partial tumor responses were noted, but one patient had a minor response, and four patients had stable disease lasting at least 6 months. Conclusions: The MTD and recommended phase 2 doses for ABT-751 were 250 mg q.d. and 150 mg b.i. d. on a 7-day schedule given every 3 weeks, due to subsequent cycle toxicities at 175 mg b.i. d. dosing. Toxicities were abdominal pain, constipation, and neuropathy.
Comparative Search of Entities

Nowadays, every manufacturer or retailer displays their product information on various websites. The customer has to visit, the number of such web pages to choose the right product, because the information is not available at one place. There are some websites that show such information in one place, but they are product specific and in general information is manually updated. In this paper, we propose a novel concept of web-spreadsheet, which displays product information by crawling through related web pages and generates information like a spreadsheet where each row represents product information and each column represents product attributes. We are extracting the product name of specified product class using decision tree-based classifier by features obtained using Part of Speech (POS) tagging and distance measure. It also extracts the value-measure pairs of preset attributes using distance measure, POS tagging and Data type. This approach will save a lot of time of comparing different products and cus.
Early life and current determinants of bone in South African children of mixed ancestral origin

Background: The influence of early life factors on the bone mineral density of children has been identified, however the contribution of these determinants may vary. Aim: The study investigated determinants of bone mineral content (BMC) in South African children of mixed ancestral origin. Subjects and methods: Early life data including birth weight, maternal alcohol consumption and smoking during pregnancy were collected on 9-year-old children of mixed ancestral origin (n = 64). Grip strength was measured, and physical activity, housing density and dietary data were collected. Whole body BMC (WB BMC), fat-free soft tissue and fat tissue were measured using dual energy X-ray absorptiometry. Results: Maternal alcohol consumption during pregnancy was associated with WB BMC, however after adjusting for possible confounders, this was no longer significant. When combined with gender, gestational age and maternal BMC in a multiple regression, maternal alcohol consumption during pregnancy could explain 20% of the variance in the WB BMC, however when current height was included in the model, the contribution of the other factors was insignificant. There was however a significant correlation between current height and birth weight (r = 0.34; p < 0.01) and alcohol consumption during pregnancy (r = 0.34; p < 0.05). A model consisting of current factors such as age, weight, gender, grip strength and calcium intake was able to explain 81.5% of the variance. Housing density was negatively correlated with WB BMC (r =–0.11; p = 0.05). Conclusion: These data suggest that although early life factors may contribute indirectly to the bone mass of children of mixed ancestral origin, the contribution of current factors is greater. In addition, environmental factors such as housing density have a direct effect on bone mass, independent of body size.
Results-Based Management and Thai Bureaucracy Development Approaches

This article focuses on the history and results-based management of thinkers and scholars in various aspects together with other ideas and criticism relating to the results-based management of Thai Bureaucracy and directions in the administration of Thai Bureaucracy. It indicates that Thai Bureaucracy needs structural reformations and co-operation between governmental departments in the same direction. And part of the reform of bureaucracy needs the modern principles of the results-based management to be adapted to use. And Thai Bureaucracy in the 21st century has to focus on the end of desirable needs. So, the development of Thai Bureaucracy requires cooperation by focusing on the important effect and quickness more than competition and changes happening in the globalization age at the moment.
Changes in Functional Ability from Ages 70 to 75

The purpose of this article is (a) to describe changes in functional ability from the age of 70 to 75 years, (b) to examine whether a new functional ability measure is a good predictor of dependency, and (c) to examine whether sociodemographic factors are associated with transitions. The investigation is part of the longitudinal study of the 1914 population in Glostrup, Denmark, and comprised 576 men and women who were interviewed in their homes about functional ability, social situation, and so forth when they were 70 and 75 years old. Tiredness in mobility and daily activities measured by two functional ability scales at age 70 were independent predictors of need for help in mobility and daily activities at age 75. Among the sociodemographic variables, education among women and income among men were found to be independent predictors of dependency at age 75.