Miracle-dz/UniFAR-FTUs huggingface dataset:
The Collection, Management and Utilization of the Filing Information of Irrigation Technology

The filing information is a kind of information resources. The collection of the filing information of irrigation is very important not only to designed work of this unit, but also to technical personnel in a specific field to study , accumulate and improve self's quality. Every designed room is required to deliver accurate and intact irrigation information to information room to be filed and preserved.
Novel HER2 selective tyrosine kinase inhibitor, TAK‐165, inhibits bladder, kidney and androgen‐independent prostate cancer in vitro and in vivo

Purpose: TAK‐165 is a new potent inhibitor of human epidermal growth factor receptor 2 (HER2) tyrosine kinase. Several reports suggest HER2 expression in bladder cancer, renal cell carcinoma (RCC) and androgen‐independent prostate cancer. We therefore investigated the antitumor effect of TAK‐165 on these urological cancer cells.
Efficiency enhancement and polarization detection capability of photodiode by accumulating local electric field on the metal electrodes

By chiral-shape patterns over finger-type electrodes of conventional photodiode, for the first time, record high >80% external quantum efficiency (EQE) and polarization detection capability are successfully achieved simultaneously through the self-accumulated local electric field due to strong local surface plasmon resonance (LSPR). Device has expected high efficiency to absorb the incident visible energy profiting the visible applications potentially, such as artificial eyes. Extraordinary transmission phenomenon can be well examimed indepth by both theoretical and experimental results discussed in this work.
SHOULD I STAY OR SHOULD I GO? INFORMAL SOCIAL TIES AND ENTREPRENEURSHIP CHOICES: EVIDENCE FROM THE MUTUAL FUND INDUSTRY.

The article discusses informal social ties and entrepreneurship decisions within the mutual fund industry. Many entrepreneurs come from organizations that are already existing and it is not well-known why these individuals decide to leave their organizations to start their own companies. Incentives that could drive a person towards entrepreneurship include the pursuit of profit and gaining autonomy. Research was conducted into these theories where the organization provides higher compensation and greater discretion.
Treatment of Intra-Abdominal Abscesses Caused by Candida albicans with Antifungal Agents and Recombinant Murine Granulocyte Colony-Stimulating Factor

ABSTRACT The aim of the present study was to assess the influence of immunomodulation of host defense with recombinant murine granulocyte colony-stimulating factor (rmG-CSF) on intra-abdominal abscesses caused by Candida albicans. Mice received prophylaxis or therapy with 1 μg of rmG-CSF/day in the presence or absence of antifungal treatment consisting of amphotericin B (0.75 mg/kg of body weight/day) or fluconazole (50 mg/kg/day). The number of Candida CFU in abscesses was significantly reduced (P < 0.05) in mice receiving rmG-CSF prophylaxis (day −1 or day −1 through 2) compared with controls on day 8 of infection. Administration of rmG-CSF therapy alone (for 5 days starting on day 4 of infection) had no influence on the number of Candida CFU in abscesses. Amphotericin B treatment was significantly more effective than fluconazole treatment (3.41 log CFU/abscesses; 95% confidence interval [CI], 3.17 log CFU/abscesses; 3.65 versus 3.90 log CFU/abscesses; 95% CI, 3.66 log CFU/abscesses, 4.16 log CFU/abscesses; P < 0.05). Therapeutic administration of rmG-CSF in conjunction with an antifungal agent showed a tendency towards a further reduction of Candida CFU in abscesses than antifungal treatment only. In conclusion, in this experimental model of intra-abdominal Candida abscesses, rmG-CSF administration did not have a detrimental influence on the course of infection. Amphotericin B treatment was most effective, and additional rmG-CSF therapy did not antagonize the effect of antifungal treatment. In contrast, addition of rmG-CSF therapy to antifungal treatment might further enhance the beneficial effect of the antifungal agent.
Nationalistic Sentiments of Chinese Consumers: The Effects and Determinants of Animosity and Consumer Ethnocentrism

ABSTRACT The purpose of this study is to examine the antecedents of consumer ethnocentrism and test the effects of animosity and consumer ethnocentrism on the purchase of foreign products in China. A questionnaire survey (N = 600) was conducted in Shanghai in 2005 using the mall-intercept survey technique. The results indicate that the effects of animosity and consumer ethnocentrism are significant in the case of Japanese and U.S. products in China, and that Chinese consumer ethnocentrism is a combination of patriotism and negative internationalism. Patriotism is positively correlated with consumer ethnocentrism, but is negatively correlated with animosity. As compared to patriotism, the total effect of exclusionism on the willingness to buy foreign products is much stronger.
The recognition component of the N‐end rule pathway.

The N‐end rule‐based degradation signal, which targets a protein for ubiquitin‐dependent proteolysis, comprises a destabilizing amino‐terminal residue and a specific internal lysine residue. We report the isolation and functional analysis of a gene (UBR1) for the N‐end recognizing protein of the yeast Saccharomyces cerevisiae. UBR1 encodes a approximately 225 kd protein with no significant sequence similarities to other known proteins. Null ubr1 mutants are viable but are unable to degrade the substrates of the N‐end rule pathway. These mutants are partially defective in sporulation and grow slightly more slowly than their wild‐type counterparts. The UBR1 protein specifically binds in vitro to proteins bearing amino‐terminal residues that are destabilizing according to the N‐end rule, but does not bind to otherwise identical proteins bearing stabilizing amino‐terminal residues.
An update on HIV-1 antiretroviral resistance

Purpose of reviewEmergence of antiretroviral drug resistance limits the benefit of antiretroviral therapy for many patients. Despite considerable progress, much remains to be learned about drug resistance. Studies published over the last year have contributed significantly to the understanding of HIV-1 drug resistance. Recent findingsThe prevalence of antiretroviral drug resistance is rising among persons newly infected with HIV-1 in the US and Europe. In this setting, resistance testing prior to starting antiretroviral therapy has been shown to be cost-effective. Immunologic stability despite emergence of drug resistance on a failing antiretroviral regimen may be due to lower levels of immune activation by drug-resistant virus. Recent studies show that continued use of lamivudine contributes to partial viral suppression despite the presence of lamivudine resistance. New, more sensitive assays for detecting drug resistance mutations highlight the problem of resistance to nonnucleoside reverse transcriptase inhibitors following use of single-dose nevirapine for prevention of mother-to-child transmission. Data from laboratory and clinical studies provide a more complete understanding of resistance to the protease inhibitor atazanavir and to the fusion inhibitor enfuvirtide. SummaryNew data on HIV-1 drug resistance continue to improve our understanding of the epidemiology, pathogenesis and management of antiretroviral drug resistance.
Calculation and Prediction of Fugacity and Activity Coefficients in Binary Mixtures, using a Self-Regulated Fretwidth Harmony Search Algorithm

El presente articulo de investigacion propone el uso de la nueva variante del algoritmo hs (Harmony Search), esto es, el sfhs (Self-Regulated Fretwidth Harmony Search Algorithm) para el calculo y prediccion de coeficientes de fugacidad y actividad en mezclas binarias. La seleccion de los parametros de ejecucion del algoritmo sfhs se realizo con base en pruebas preliminares con diferentes funciones de prueba estandar. Se seleccionaron sistemas previamente reportados en la literatura, a 25 oC y 40 oC, y a presiones bajas y moderadas. Adicionalmente, se seleccionaron dos solutos diferentes: dioxido de carbono y etano. Se tomaron diferentes solventes, polares y no polares, con propositos comparativos. Los coeficientes de actividad y fugacidad se calcularon utilizando la ecuacion de estado Redlich-Kwong y la regla de Lewis, junto con el algoritmo sfhs para los dos solutos en fase vapor. La consistencia de los coeficientes de actividad se analizo mediante la estrategia de Redlich-Kister. Se obtuvieron resultados muy cercanos a los encontrados experimentalmente por otros autores y en su mayoria, no difirieron en mas de una unidad porcentual.
Cardiovascular Disease Risk Factor Variables at the Preschool Age: The Bogalusa Heart Study

SUMMARYAs part of a study to describe the early natural history of atherosclerosis, 714 children, 2'/2 to 51/2 years of age, were examined. Height, weight, triceps skinfold, blood pressure, serum lipids and lipoproteins, and a complete physical examination were obtained on each child. Black children were both taller and heavier than white children, but triceps skinfolds were greater for whites. Mean blood pressure readings obtained on each of three instruments showed different levels of blood pressure. The Infrasonde gave the lowest readings while the Baumanometer gave the highest, and an age gradient was observed only for the Infrasonde. Multiple regression analysis indicated that 12% to 22% of the variability of blood pressure could be explained by selected independent variables. Serum levels of total cholesterol,B-lipoproteins and a-lipoproteins were slightly higher in black boys than white boys. The reverse was true for triglycerides and pre-3-lipoproteins. For triglycerides, significant racial and sex effects and a relationship with weight relative to height (W/H2) were noted. Age and W/H2 were positively associated with pre-fl-lipoproteins. When the preschool-aged children are compared to our previously studied school-aged population, the magnitude of the interaction of the risk factor variables tends to increase with age, suggesting that environmental factors tend to exert an increasing effect.
Correlation between three glycometabolic-related hormones and muscle glycolysis, as well as meat quality, in three pig breeds.

BACKGROUND The present study aimed to evaluate the correlations among muscle concentrations of three glycometabolic-related hormones (insulin, epinephrine and glucagon), muscle glycolysis and meat quality in representative muscles of either glycolytic or oxidative types. Moreover, the relative glycometabolic-related gene expression was measured. One Western crossbreed DLY (Duroc × (Landrace × Yorkshire)), one crossbreed with half-Chinese native-pig origin DL (Duroc × LiangShan) and one pure Chinese native pig TP (Tibetan pig) were used in the present study. RESULTS Among the three breeds, DLY had the greatest glucagon and epinephrine (P < 0.01). Compared with DLY, TP and DL had lower lactic acid concentrations, showing lower glycolytic potentials (GP), greater ultimate pH values (P < 0.01) and lower relative expression levels of glycometabolic-related genes (GYS1, PRKAG3 and PKM2). Compared with the glycolytic muscle (musculus longissimus dorsi), oxidative muscle PM (musculus psoas major) had lower glucagon and epinephrine contents, lower GP and better meat quality. The concentration of glycometabolic-related hormones in the muscle had significant correlations with muscle glycolysis, meat pH and lightness. CONCLUSION The results obtained in the present study imply that glucagon and epinephrine levels could be used to indicate early glycolytic metabolism during postmortem. These findings may be helpful in identifying pork with undesirable quality traits. 2016 Society of Chemical Industry.
Nonlinear MIMO: affordable MIMO technology for wireless sensor networks

We consider a sensor network, where an access point (AP) communicates with many sensor nodes (SN), which are simple, cheap, low-complexity and low-power communication nodes. Such systems typically use nonlinear modulation and detection, due to their low power consumption. Increasing their performance by means of multiple antennas at the AP and the SNs has not been considered, since this would violate the stringent power and cost constraints at the SN. We consider SNs with MIMO receivers that perform a nonlinear operation on the complex-valued received signal (amplitude or phase detection). These receivers enjoy the low-cost, low-power, low-complexity characteristics that are crucial for a sensor network. Such nonlinear MIMO systems are first introduced and studied here. They bring the high-rate, high-performance world of MIMO systems and the low-cost, low-complexity world of sensor networks together. We only consider the single-user MIMO system between the AP and one SN, and study the fundamental limits of such systems. We compute achievable rates under perfect and noisy CSI at the SN, and observe that these systems also achieve spatial multiplexing gain, albeit different to legacy linear MIMO systems. We quantify and analyze these gains using numerical means, and give insight into the effect of the nonlinearity on the information theoretic limits of nonlinear MIMO systems.
An architectural framework for data link layer security with security inter-layering

Security issues in the data link layer have not received much attention while network security problems have been studied and addressed in the application, transport, and network layers. This paper proposes a new security inter-layering approach to secure the data link layer in Internet protocol (IP) over Ethernet networks. In the data link layer, the authors propose to utilize secure namespaces instead of media access control (MAC) addresses to identify network devices, which also provides the means to bind the data link layer and other layers securely. Moreover, the authors present the network structure to provide link-to-link security and the key establishment protocol to generate security parameters in the data link layer.
The influence of the strategic planning process on strategic change

This paper proposes that organizational decision‐makers exist in a market for strategic issues where different internal and external trends and developments compete for decision‐makers' attention. The paper describes how an organization's strategic planning process affects the set of strategic issues that do capture decision‐makers' attention. It explains how characteristics of the strategic issue array translate into effective and timely initiation and implementation of strategic change.
Generation and CharaCterization of KnoCKout MiCe and analysis of Patient Material deMonstrates a role for tissue inhibitor of MetalloProteinases 4 ( Timp 4 ) in the CardiovasCular systeM and tuMor Metastasis

ilpo Koskivirta. Generation and Characterization of Knockout Mice and Analysis of Patient Material Demonstrates a Role for Tissue Inhibitor of Metalloproteinases 4 (Timp4) in the Cardiovascular System and Tumor Metastasis (2012). Department of Medical Biochemistry and Genetics, University of Turku, 20520 Turku, Finland. This thesis focuses on tissue inhibitor of metalloproteinases 4 (TIMP4) which is the newest member of a small gene and protein family of four closely related endogenous inhibitors of extracellular matrix (ECM) degrading enzymes. Existing data on TIMP4 suggested that it exhibits a more restricted expression pattern than the other TIMPs with high expression levels in heart, brain, ovary and skeletal muscle. These observations and the fact that the ECM is of special importance to provide the cardiovascular system with structural strength combined with elasticity and distensibility, prompted the present molecular biologic investigation on TIMP4. In the first part of the study the murine Timp4 gene was cloned and characterized in detail. The structure of murine Timp4 genomic locus resembles that in other species and of the other Timps. The highest Timp4 expression was detected in heart, ovary and brain. As the expression pattern of Timp4 gives only limited information about its role in physiology and pathology, Timp4 knockout mice were generated next. The analysis of Timp4 knockout mice revealed that Timp4 deficiency has no obvious effect on the development, growth or fertility of mice. Therefore, Timp4 deficient mice were challenged using available cardiovascular models, i.e. experimental cardiac pressure overload and myocardial infarction. In the former model, Timp4 deficiency was found to be compensated by Timp2 overexpression, whereas in the myocardial infarct model, Timp4 deficiency resulted in increased mortality due to increased susceptibility for cardiac rupture. In the wound healing model, Timp4 deficiency was shown to result in transient retardation of re-epithelialization of cutaneous wounds. Melanoma tumor growth was similar in Timp4 deficient and control mice. Despite of this, lung metastasis of melanoma cells was significantly increased in Timp4 null mice. In an attempt to translate the current findings to patient material, TIMP4 expression was studied in human specimens representing different inflammatory cardiovascular pathologies, i.e. giant cell arteritis, atherosclerotic coronary arteries and heart allografts exhibiting signs of chronic rejection. The results showed that cardiovascular expression of TIMP4 is elevated particularly in areas exhibiting inflammation. The results of the present studies suggest that TIMP4 has a special role in the regulation of tissue repair processes in the heart, and also in healing wounds and metastases. Furthermore, evidence is provided suggesting the usefulness of TIMP4 as a novel systemic marker for vascular inflammation.
Hematoendothelial Differentiation of Human Embryonic Stem Cells

Human embryonic stem cells (hESCs) represent a unique population of cells capable of self‐renewal and differentiation into all types of somatic cells, including hematopoietic and endothelial cells. Since the pattern of hematopoietic and endothelial development observed in the embryo can be reproduced using ESCs differentiated in culture, hESCs can be used as a model for studies of specification and diversification of hematoendothelial progenitors. In addition, hESCs can be seen as a scalable source of hematopoietic and endothelial cells for in vitro studies. This unit describes a method for efficient differentiation of hESCs into hematopoietic progenitors and endothelial cells through coculture with mouse OP9 bone marrow stromal cells, as well as an approach for their analysis and isolation. Support protocols are provided for culture of mouse embryonic fibroblasts, evaluation of hematopoietic and endothelial differentiation by flow cytometry and colony‐forming assay, removal of OP9 cells, and propagation of hESC‐derived endothelial cells. Curr. Protoc. Cell Biol. 36:23.6. 1‐23.6. 28. © 2007 by John Wiley & Sons, Inc.
The relationship between the board characteristics and the risk of material misstatement

This paper chose corporate governance as the starting point, combined with the characteristics of China's current board of directors of listed companies and the risk of material misstatement, and tries to find out the correlation between the two.In this paper, empirical research and normative research method are both used. The listed companies which are warned by the China Securities Regulatory Commission, Shanghai Stock Exchange, Shenzhen Stock Exchange because of irregularities are selected. The board size, proportion of independent directors, the board meetings, audit committees, etc. such the Board characterized as explanatory variable, after controlling the firm size, profitability and other factors, the Logistic regression model was constructed. The empirical results show: board size, the board meetings, audit committees and other factors at different levels of impact on risk of material misstatement.
Segmentation strategies for non‐profits: mining the emerging market of “black gold”

Purpose – The purpose of this article is to present a strategic conceptual framework for targeting and mining the emerging market segment of Black philanthropy (black gold). Design/methodology/approach – This strategic and normative conceptualization utilizes a socio‐historical and socio‐cultural perspective to posit the black gold construct and recommend tactics for mining it.Findings – Black communities have historically engaged in social justice and self‐help activities for racial equality and advancement and with increasing levels of wealth accumulation now comprise a significant market for philanthropic giving for domestic and global non‐profit organizations. However, in light of Black America's tortured socio‐historical experience and racial/cultural identity, non‐profits must devise a historically‐informed and culturally‐nuanced strategy of relationship marketing to mine the emerging market of black gold.Practical implications – Domestic and international non‐profits can utilize the proposed strateg.
A practical analysis of the elliptic curve factoring algorithm

Much asymptotic analysis has been devoted to factoring algorithms. We present a practical analysis of the complexity of the elliptic curve algorithm, suggesting optimal parameter selection and run-time guidelines. The parameter selection is aided by a novel use of Bayesian statistical decision techniques as applied to random algorithms. We discuss how frequently the elliptic curve algorithm succeeds in practice and compare it with the quadratic sieve algorithm.
Fraud in Workers' Compensation Payroll Reporting: How Much Employer Fraud Exists? How are Honest Employers Affected?

It has long been suspected that a fraction of employers fraudulently under-report and misreport payroll for calculation of workers’ compensation premium or illegally forgo purchasing workers’ compensation insurance altogether. Previously, the Commission on Health and Safety and Workers’ Compensation (CHSWC) contracted with the University of California, Berkeley to develop a pilot project and analyze the degree to which employers go fail to secure coverage (Neuhauser, 1998). The present study extends that prior study to include the impact of fraudulent under-reporting and misreporting of payroll used by insurers to calculate premiums. During the period studied for this report, 1997-2002, rates were initially low (for California) and increased rapidly. Subsequent to the study period rates continued to increase through 2004 and then dropped to near earlier levels. This study examines the extent of fraudulent reporting and the impact of the rapid increase in premium rates on employer fraudulent behavior.
Limiting Privacy Breaches in Differential Privacy

In recently years, privacy-preserving data mining has become more import and attractedmore attention from data mining community. Among the existing privacy preserving models, ��-differential privacy provides the strongest privacy guarantees and has no assumption about the adversary's background information and compute ability. However, howto set �� to satisfy privacy is still an open problem. In this paper, we propose a tactic, named LPB (Limiting Privacy Breaches), to set the privacy parameter intuitively. LPB ensures that, if the prior belief about individual is bounded by some threshold, the posterior belief, after given the published randomized result, is no more than another threshold. Keywords-component; differential privacy;privacy breaches; privacy-preserving data mining