Miracle-dz/UniFAR-FTUs huggingface dataset:
Sustainable Capital Market and the Attributes of Business Models in the Crisis

I n the current economic crisis, paradigms in management sciences are verified. The way business is perceived is changing and a new look is taken at the mechanisms of operation of modern companies. Entrepreneurs are looking for solutions that ensure their survival in this difficult period, and their success is determined by the consistent, strategic revival of the companies they manage. Assuming that a business model and its implementation is now a source of achieving competitive advantage and a tool for the creation of company value, one must ask which attributes of the business model are the most up-to-date so that they could fulfill the expectations of the market, which is in the phase of the economic and financial crisis. This also requires an understanding of the market and the ability of companies to act properly so that in the current economic situation threats could be transformed into opportunities of a new dimension of modern company development. The author believes that a source of ensuring that company value is created and business continuity is maintained is the design and implementation of a business model based on the principles of strategic sustainability and balance, so a sustainable business model. The purpose of the paper is to present the selected attributes of capital market and attributes of sustainable business models and to define basic boundary conditions necessary to implement these models in the current economic and financial crisis.
H5N1 influenza virus and the safety of plasma products

BACKGROUND: The ever‐increasing number of human H5N1 influenza virus infections may enable these viruses to acquire the ability to spread effectively among humans and potentially to cause a pandemic. Recently, more systemic virus dissemination was reported during H5N1 virus infection of humans, resulting in significant virus concentrations also in the blood. The observation has raised concerns about the safety of labile blood products for transfusion and consequentially also for plasma derivatives. To confirm the safety margins of plasma products, dedicated virus inactivation processes used during their production were investigated for their effectiveness in inactivating this virus of recent concern.
A Nuclear Localization Signal in Herpesvirus Protein VP1-2 Is Essential for Infection via Capsid Routing to the Nuclear Pore

ABSTRACT To initiate infection, herpesviruses must navigate to and transport their genomes across the nuclear pore. VP1-2 is a large structural protein of the virion that is conserved in all herpesviruses and plays multiple essential roles in virus replication, including roles in early entry. VP1-2 contains an N-terminal basic motif which functions as an efficient nuclear localization signal (NLS). In this study, we constructed a mutant HSV strain, K.VP1-2ΔNLS, which contains a 7-residue deletion of the core NLS at position 475. This mutant fails to spread in normal cells but can be propagated in complementing cell lines. Electron microscopy (EM) analysis of infection in noncomplementing cells demonstrated capsid assembly, cytoplasmic envelopment, and the formation of extracellular enveloped virions. Furthermore, extracellular virions isolated from noncomplementing cells had similar profiles and abundances of structural proteins. Virions containing VP1-2ΔNLS were able to enter and be transported within cells. However, further progress of infection was prevented, with at least a 500- to 1,000-fold reduction in the efficiency of initiating gene expression compared to that in the revertant. Ultrastructural and immunofluorescence analyses revealed that the K.VP1-2ΔNLS mutant was blocked at the microtubule organizing center or immediately upstream of nuclear pore docking and prior to gene expression. These results indicate that the VP1-2 NLS is not required for the known assembly functions of the protein but is a key requirement for the early routing to the nuclear pore that is necessary for successful infection. Given its conservation, we propose that this motif may also be critical for entry of other classes of herpesviruses.
Expression of parathyroid hormone-related peptide messenger ribonucleic acid in developing kidney.

BACKGROUND Parathyroid hormone (PTH)-related peptide (PTHrP), originally identified as a causative agent of hypercalcemia of malignancy, has been implicated in the regulation of growth and differentiation of endochondral bone, hair follicle, and breast as an autocrine/paracrine factor. Although some experiments indicate that PTHrP works as a growth factor for primary renal cells in vitro, the role of PTHrP in the kidney in vivo is not yet known. METHODS We examined the amounts of PTHrP and PTH/ PTHrP receptor (PTHR) mRNA in the mouse kidney developmental process by reverse transcription-polymerase chain reaction, and investigated which cells produce PTHrP and PTHR in vivo by in situ hybridization. RESULTS We observed high levels of PTHrP mRNA during mouse kidney maturation. PTHrP mRNA was expressed in the collecting duct, urothelium of the pelvis, and immature elements in the cortex of the developing kidney, including the S-shaped body, ureteric bud, and glomerulus. However, the expression of PTHR mRNA was lower during maturation than after the completion of the maturation process, and it was not detected in the collecting duct, urothelium of the pelvis, or nephrogenic zone in embryonic day 16 or 0-day-old mouse kidneys. CONCLUSION These findings suggest that PTHrP has a role in mouse kidney maturation or glomerular development.
De verdeling van woningen : een kwestie van onderhandelen

• A submitted manuscript is the author's version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers.
Comparative human resource management: an introduction

This is the fi rst book to bring together, systematically, expert researchers studying comparative human resource management (HRM). The need for a comparative book is, we believe, manifest, and the subject is increasingly researched and taught, either as part of a general HRM or international HRM course. This Handbook of Research on Comparative Human Resource Management draws on the work of some of the world’s leading researchers to present the current state of the art to academic scholars and practitioners. HRM as a subject for study and teaching was identifi ed and popularised in the United States in the late 1970s and early 1980s, encapsulated in two famous textbooks (Beer et al., 1985; Fombrun et al., 1984). The two books took diff erent approaches, but both diff erentiated HRM from personnel management (the administration of employment). They argued that the latter involved running, monitoring and controlling the employment systems within the organisation, whilst HRM involved more integration of personnel policies across functions and with the corporate strategy (with HRM being the downstream function); a greater role for line managers; a shift from collective to individual relationships; and an accent on enhancing company performance. In HRM workers are a resource: they ‘are to be obtained cheaply, used sparingly and developed and exploited as fully as possible’ (Sparrow & Hiltrop, 1994: 7) in the interests of the organisation. The processes of managing people in a systematic and consistent way with the intention of ensuring their eff ective contribution to the success of the organisation – in other words: human resource management – utilises the same processes in every case: a workforce has to be recruited, deployed and assessed, trained, paid, all of this within conditions that allow motivation to develop and be sustained. The way that HRM and these processes are thought about and the way that they are practised, however, varies from context to context. One of the major contexts is the country in which they operate. Because most studies of HRM take place within a single national context, commentators have long been aware of the diff erences in HRM policies and
The Stealth Sodium Revolution

Sodium has become one of a handful of sensitive nutrients in the public spotlight, according to major food company executives who attended the 2011 National Nutrient Databank Conference in Bethesda, Md. The conference is supported annually by the Agricultural Research Service (ARS) Nutrient Data Laboratory and the agency's Food Surveys Research Group, as well as other organizations. ARS is USDA's principal intramural scientific research agency. At the conference, three major food companies described long-term "silent" sodium-reduction plans. One company reported already having removed 2 million pounds of salt from retail food brands in less than 10 years. Another announced plans to reduce sodium in prepared foods by 10 percent before 2015. All of the food companies talked about the need to give consumers time to "adapt their taste buds" to less salt in their retail foods.
Putting Intellectual Capital to work: Utilizing the Intellectual Potential Framework

The critical point of strategy is making it happen. This paper is about putting strategies to work in the every day life of a company using the previously developed Intellectual Potential Framework. Four change management projects, in an International Engineering Company – Alfa Laval, are analysed. All cases involve designing and implementing strategies across the functional line organisation with the use of a process oriented approach. Results provide clear evidence of the advantage of applying strategies and performance measures to business processes rather than to the formal line organisation. Further the projects indicate business benefits measured as gross margin increases of the 40-70 M€ businesses in the range of 4-7M€. Finally the study indicates a lasting effect - the changes stick to the organisation after the project conclusion.
High-Speed Light-Emitting Diodes Emitting at 500 nm With 463-MHz Modulation Bandwidth

Light-emitting diode (LED) is one of the most important light sources due to its low power consumption and long lifetime. In this letter, we present the high-frequency characteristics of GaN-based green LEDs with different aperture diameters. In order to get higher current density, we use ring-shaped electrode to confine the current injection. Unlike conventional LEDs, we only use its natural feature to get a high modulation bandwidth. The LEDs investigated have a peak emission wavelength of 500 nm. The highest optical 3-dB modulation bandwidth is ~463 MHz at 50 mA for the 500-nm green GaN-based LED with an aperture diameter of 75 μm. It is the highest bandwidth yet reported for the green GaN-based LEDs. The LED also exhibits a relatively high output power of ~1.6 mW at 50 mA as compared with other high-speed LEDs. Such the LEDs can be applied to plastic optical fiber and visible light communication in the future.
Data Synchronization Model for Heterogeneous Mobile Databases and Server-side Database

Mobile devices, because they can be used to access corporate information anytime anywhere, have recently received considerable attention, and several research efforts have been tailored towards addressing data synchronization problems. However, the solutions are either vendor specific or homogeneous in nature. This paper proposed Heterogeneous Mobile Database Synchronization Model (HMDSM) to enable all mobile databases (regardless of their individual differences) and participate in any data synchronization process. To accomplish this, an experimental approach (exploratory and confirmatory) was employed. Also existing models and algorithms are classified, protracted and applied. All database peculiar information, such as trigger, timestamp and meta-data are eliminated. A listener is added to listen to any operation performed from either side. To prove its performance, the proposed model underwent rigorous experimentation and testing. X2 test was used to analyze the data generated from the experiment. Results show the feasibility of having an approach which can handle database synchronization between heterogeneous mobile databases and the server. The proposed model does not only prove its generic nature to all mobile databases but also reduces the use of mobile resources; thus suitable for mobile devices with low computing power to proficiently process large amount of data. Â© 2015 The Science and Information (SAI) Organization Limited.
Correlates of Colorectal Cancer Screening Among South Asian Immigrants in the United States

Background: South Asians are a rapidly increasing population in the United States. Little is known about influences on their cancer screening behaviors, an important prerequisite to designing culturally appropriate education. Objective: The purpose of this study was to evaluate rates and correlates of colorectal cancer (CRC) screening, knowledge, and beliefs among South Asians. Methods: A subsample of those 50 years or older (n = 275) was drawn from the South Asian Health Descriptor Study, an assessment of multiple health indicators conducted in Chicago, Illinois. Results: Indians represented 87% of the sample; 2.2% of participants believed that they were at risk for CRC; 8% reported a past stool blood test (SBT); and 13.6% had had a sigmoidoscopy or colonoscopy. Language acculturation (adjusted odds ratio [AOR], 1.93; confidence interval [CI], 1.1–3.5) and medical mistrust (AOR, 0.243; CI, 0.091–0.650) were significantly related to SBT completion. Language acculturation (AOR, 3.30; CI, 1.8–5.5), income (AOR, 2.70; CI, 1.0–7.1), living in the United States for more than 5 years (AOR, 8.6; CI, 1.9–14.5), perception of CRC risk (AOR, 8.9; CI, 1.1–17.7), and past SBT (AOR, 5.0; CI, 1.8–14.0) were significantly related to endoscopic cancer screening. Conclusions: Facilitators and barriers to different CRC tests vary. Education to increase CRC screening may need to be targeted to culture and specific barriers to each screening test rather than generic messages for all screening tests. Implications for Practice: Because barriers to CRC screening may differ among people based on the specific screening test being recommended. Primary care practitioners should recognize this fact and identify different barriers to enhance adherence to screening recommendations.
A preliminary disease survey in the wild Nile crocodile (Crocodylus niloticus) population in the Okavango Delta, Botswana

INTRODUCTION Since the development of the crocodile farming industry in the 1980s, a number of studies have been carried out worldwide on diseases in farmed crocodiles. Very little, however, is known about the diseases of wild crocodilians, particularly wild Nile crocodiles. Wild crocodiles are often difficult to study owing to the remoteness of the areas in which they occur. The initial objective of this study was to determine disease prevalence in the wild Nile crocodile population in the Okavango Delta. However, several factors made this difficult: (i) Very few serological tests have been developed for crocodile diseases. Consequently a serological survey is of very limited value. (ii) Virus isolation is unavailable due to the lack of crocodile cell lines in veterinary diagnostic laboratories. (iii)Sick crocodiles are difficult to identify by observation. Under farmed conditions they often stop eating but show no other clinical signs and therefore are not noticed to be unhealthy until they are found dead. Diseases causing visible external lesions, for example pox virus infection, are the obvious exception. (iv)Clinical examination has several limitations: cardiac and respiratory rates are variable according to conditions, and are strongly influenced by capture stress. Because crocodiles are poikilothermic, body temperature cannot be used as a diagnostic tool. (v) Sick/weak crocodiles are unlikely to survive for long due to predation. Therefore, the likelihood of encountering these individuals in a capture and release survey is low. (vi)Owing to research permit limitations no crocodiles could be sacrificed for histopathological and parasitological examination. In view of these limitations, it was postulated that a low incidence of diseases would be found in the Okavango population during a capture and release survey. However, it was possible to do a more accurate survey for mycoplasmosis and haemogregarine infection thanks to the availability of diagnostic tests. In addition, ectoparasites, in the form of leeches, were easy to find, remove and count per individual. MATERIALS AND METHODS
On smooth solutions to one phase free boundary problem in R n

We construct a smooth axially symmetric solution to the classical one phase free boundary problem in R, n ≥ 3. Its free boundary is of “catenoid” type. This is a higher dimensional analogy of the HauswirthHelein-Pacard solution [18] in R. The existence of such solution is conjectured in [18, Remark 2.4]. This is the first nontrivial smooth solution to the one phase free boundary problem in higher dimensions.
Hemodynamic Actions of a Synthetic Atrial Natriuretic Factor

Summary: The recently discovered atrial natriuretic factor (ANF), as well as synthetic ANF, has been demonstrated to produce diuresis and vasodilation. However, the vascular actions appear to be selective. In view of this apparent relative specificity, the hemodynamic actions of synthetic ANF (atriopeptin II, 23 amino acid rat sequence) were examined in intact animals and in vascular beds as well as in isolated cardiac preparations. Administration of 1–100 μg/kg of ANF i.v. into conscious spontaneously hypertensive rats (SHRs) resulted in a dose-related fall in blood pressure. Heart rate decreased at the lowest dose. Cardiac output was depressed. Infusion of 1 μg/kg/min also reduced blood pressure and decreased cardiac output slightly (15%). Intra-arterial (i.a.) administration or i.v. injection of ANF into the blood supply of a kidney of anesthetized SHRs augmented renal blood flow and reduced renal vascular resistance. In contrast, i.a. administration into the hind-quarters failed to increase blood flow or decrease resistance of this bed significantly. The specific dopamine1 (DA1)-receptor agonist SKF 82526 was examined for comparative purposes and was found to augment both renal and hindquarter blood flow following i.a. administration. The renal vasodilator actions of SKF 82526 but not ANF were antagonized by the specific DA1-receptor blocker SCH 23390 (hindquarter effects were not evaluated). ANF did not affect the force of contraction or rate of beating of isolated guinea pig atria or isolated hearts and therefore does not appear to possess direct inotropic or chronotropic properties. In conclusion, ANF lowered blood pressure in conscious SHRs; the lowering of pressure was accompanied by a slight fall in cardiac output, but there was no reflex tachycardia. The renal dilation probably contributed to the hypotensive response. The vascular actions of ANF appear to be selective in vivo as in vitro.
Secretory function of autophagy in innate immune cells

Eukaryotic cells utilize two main secretory pathways to transport proteins to the extracellular space. Proteins with a leader signal sequence often undergo co‐translational transport into the endoplasmic reticulum (ER), and then to the Golgi apparatus before they reach their destination. This pathway is called the conventional secretory pathway. Proteins without signal peptides can bypass this ER‐Golgi system and are secreted by a variety of mechanisms collectively called the unconventional secretory pathway. The molecular mechanisms of unconventional secretion are emerging. Autophagy is a conserved bulk degradation mechanism that regulates many intracellular functions. Recent evidence implicates autophagy in the secretory pathway. This review focuses on potential secretory roles of autophagy and how they could modulate the functions of innate immune cells that secrete a wide range of mediators in response to environmental and biological stimuli. We provide a brief overview of the secretory pathways, enumerate the potential mechanistic themes by which autophagy interacts with these pathways and describe their relevance in the context of innate immune cell function.
Atherosclerotic plaque characterization: a need for a paradigm shift for prediction of risk.

the concept of the vulnerable plaque, which was defined the proclivity of a plaque towards rupture. In this formative they proposed plaque vul-nerability to be ‘presumably a dynamic, potentially reversible disorder caused by changes in the constituents of the plaque, its blood supply through vasa vasorum, or the functional integrity of the overlying endothelium’. In the this was by a series of elegant pathologic and invasive imaging evaluations of patients presenting with sudden coronary death or acute myocardial infarction (AMI), wherein distinctive anatomic features of coronary atherosclerotic plaque were often implicated at the time of or after these adverse clinical events
Farm Operator Entry and Exit Behavior: A Longitudinal Analysis

Farm structure is experiencing a persistent change. Since the early 1980s, US farms specializing in crops have constantly declined in number and grown in average size. Crop production has moved to large farms at the expense of small and medium sized farms. This shift in farm structure to more concentrated production is complex. Market forces such as technological change and changing factor input prices are likely contributors as they have been in the past. Another factor that has generated considerable interest is the role of commodity program payments. Commodity payments are tied to a farm’s current or historical production. Therefore, larger farms tend to receive the greatest share of commodity program payments. However, the extent that commodity payments have contributed to farm concentration is under debate. This project proposes to investigate the role farm characteristics, management practices, and government commodity payment programs in farm concentration by studying the entry and exit decisions of farm operators at the county level in the South Dakota. The study will use longitudinal data from the US Agricultural Census to identify farm structures, management practices and individual operator human capital and demographic characteristics. We intend to combine the agricultural census data with regional data on local economic activity, fiscal measures and natural amenities to explain farm producer’s entry and exit decisions.
Automatic negotiation: playing the domain instead of the opponent

An automated negotiator is an intelligent agent whose task is to reach the best possible agreement. We explore a novel approach to developing a negotiation strategy, a ‘domain-based approach’. Specifically, we use two domain parameters, reservation value and discount factor, to cluster the domain into different regions, in each of which we employ a heuristic strategy based on the notions of temporal flexibility and bargaining strength. Following the presentation of our cognitive and formal models, we show in an extensive experimental study that an agent based on that approach wins against the top agents of the automated negotiation competition of 2012 and 2013, and attained the second place in 2014.
Characterization of plated via hole fences for isolation between stripline circuits in LTCC packages

Reduced coupling between adjacent striplines in LTCC packages is commonly accomplished by walls made of plated via holes. In this paper, a 3D-FEM electromagnetic simulation of stripline with filled via fences on both sides is presented. It is shown that the radiation loss of the stripline and the coupling between striplines increases if the fence is placed too close to the stripline.