Miracle-dz/UniFAR-FTUs huggingface dataset:
The presence of dental disease can be a risk factor for recurrent Helicobacter pylori infection after eradication therapy: a 3-year follow-up.

BACKGROUND AND STUDY AIM We investigated whether dental disease might be associated with a higher recurrence of Helicobacter pylori infection after successful eradication by triple therapy. PATIENTS AND METHODS Consecutive patients with successful H. pylori eradication, defined by negative results for both histology and (13)C-urea breath test (UBT) performed 6 weeks after triple therapy, were enrolled in the study. Each patient was scheduled for serial UBT and dental assessments at the end of the first, second, and third years. Patients were categorized into a "dental disease" group or "no dental disease" group at the first-year follow-up. Patients in the dental disease group whose dental disease had been cured during the second- and third-year follow-up periods, were transferred to a "dental treatment" group. RESULTS The first-year H. pylori recurrence rate was higher in the 159 patients with dental disease than in those 200 patients without dental disease (13.2 % vs. 3.5 %, P < 0.001; relative risk [95 %CI], 4.2 [1.7 - 10.1]). At both the second-year and the third-year follow-up, the annual H. pylori recurrence rates were higher in the dental disease group than in the no dental disease group or dental treatment group (second year, 18.4 % vs. 2.8 % or vs. 5.7 %, P < 0.001; third year, 20 % vs. 3.8 % or vs. 6.3 %, P < 0.001). CONCLUSION The presence of dental disease could predispose to recurrent H. pylori infection after successful eradication. Dental surveillance and care after H. pylori eradication is a rational step for preventing recurrence of H. pylori, especially in those with dental diseases.
Cognitive Control: Componential and Yet Emergent

In this commentary, I will argue that the componential and emergent views of cognitive control as defined by Cooper (2010) do not necessarily oppose each other, and I will try to make a case for their interdependence. First, I will use the construct of cognitive inhibition-one of the main componential control functions mentioned in the target articles-to illustrate my line of reasoning. Then, I will comment on how some of the target articles, each from a different perspective, bring arguments in favor of this integrative view.
Range Alignment in ISAR Motion Compensation Based on Minimum Sum

A new technique is proposed for range alignment in inverse synthetic aperture radar (ISAR). The basic idea is to perform range alignment using a minimum sum criterion. By minimizing the sum of the combined envelope of two adjacent echoes, the amount of range shift between them can be automatically tracked out. The combined envelope is constructed by a `max' operation, which only reserves the larger elements of the two echoes. This algorithm has been used to process real ISAR data and the results demonstrate the effectiveness of the method
A consistent explanation of the role of the SiN composition on the program/retention characteristics of MANOS and NROM like memories

In this work, we show that a detailed atomistic model of SiN defects provides a consistent explanation of the program/erase/retention characteristics of both NROM and MANOS charge-trap cells. Our analysis of devices with SiN layers of different stoichiometry is also consistent with original KFM measurements of trapped charge drift in SiN layers.
Identification of Aichi Virus Infection by Measurement of Immunoglobulin Responses in an Enzyme-Linked Immunosorbent Assay

ABSTRACT Using inhibitory enzyme-linked immunosorbent assay, seroconversions to Aichi virus were detected in 24 (42.9%) of 56 patients with gastroenteritis in six outbreaks. Virus-specific immunoglobulin M (IgM) was detected in convalescent-phase sera from 7 of 24 patients. Of the other 17 patients, 12 developed a significant increase in both IgA and IgG levels and 5 developed a significant increase in IgG alone.
Outlier detection and removal improves accuracy of machine learning approach to multispectral burn diagnostic imaging

Abstract. Multispectral imaging (MSI) was implemented to develop a burn tissue classification device to assist burn surgeons in planning and performing debridement surgery. To build a classification model via machine learning, training data accurately representing the burn tissue was needed, but assigning raw MSI data to appropriate tissue classes is prone to error. We hypothesized that removing outliers from the training dataset would improve classification accuracy. A swine burn model was developed to build an MSI training database and study an algorithm’s burn tissue classification abilities. After the ground-truth database was generated, we developed a multistage method based on Z-test and univariate analysis to detect and remove outliers from the training dataset. Using 10-fold cross validation, we compared the algorithm’s accuracy when trained with and without the presence of outliers. The outlier detection and removal method reduced the variance of the training data. Test accuracy was improved from 63% to 76%, matching the accuracy of clinical judgment of expert burn surgeons, the current gold standard in burn injury assessment. Given that there are few surgeons and facilities specializing in burn care, this technology may improve the standard of burn care for patients without access to specialized facilities.
Inhibition of Autoimmune Type 1 Diabetes by Gastrointestinal Helminth Infection

ABSTRACT Gastrointestinal nematode infections are prevalent worldwide and are potent inducers of T helper 2 responses with the capacity to modulate the immune response to heterologous antigens. Parasitic helminth infection has even been shown to modulate the immune response associated with autoimmune diseases. Nonobese diabetic (NOD) mice provide a model for studying human autoimmune diabetes; as in humans, the development of diabetes in NOD mice has been linked to the loss of self-tolerance to beta cell autoantigens. Previous studies with the NOD mouse have shown that helminth and bacterial infection appears to inhibit type 1 diabetes by disrupting the pathways leading to the Th1-mediated destruction of insulin-producing beta cells. The aim of our study was to examine whether infection with the gastrointestinal helminths Trichinella spiralis or Heligmosomoides polygyrus could inhibit the development of autoimmune diabetes in NOD mice and to analyze the mechanisms involved in protection and the role of Th2 responses. Protection from diabetes was afforded by helminth infection, appeared to inhibit autoimmune diabetes by disrupting pathways leading to the destruction of beta cells, and was mediated by seemingly independent mechanisms depending on the parasite but which may be to be related to the capacity of the host to mount a Th2 response.
Highly Hydrophilic Proteins in Prokaryotes and Eukaryotes Are Common during Conditions of Water Deficit*

The late embryogenesis abundant (LEA) proteins are plant proteins that are synthesized at the onset of desiccation in maturing seeds and in vegetative organs exposed to water deficit. Here, we show that most LEA proteins are comprised in a more widespread group, which we call “hydrophilins. ” The defining characteristics of hydrophilins are high glycine content (>6%) and a high hydrophilicity index (>1.0). By data base searching, we show that this criterion selectively differentiates most known LEA proteins as well as additional proteins from different taxons. We found that within the genomes of Escherichia coli and Saccharomyces cerevisiae, only 5 and 12 proteins, respectively, meet our criterion. Despite their deceivingly loose definition, hydrophilins usually represent <0.2% of the proteins of a genome. Additionally, we demonstrate that the criterion that defines hydrophilins seems to be an excellent predictor of responsiveness to hyperosmosis since most of the genes encoding these proteins in E. coli and S. cerevisiae are induced by osmotic stress. Evidence for the participation of one of the E. coli hydrophilins in the adaptive response to hyperosmotic conditions is presented. Apparently, hydrophilins represent analogous adaptations to a common problem in such diverse taxons as prokaryotes and eukaryotes.
Thermally and electrically isolated single crystal silicon structures in CMOS technology

Thermally and electrically isolated single crystal silicon structures have been fabricated using a post-processing anisotropic tetramethyl ammonium hydroxide (TMAH) electrochemical etch. The process was carried out on CMOS circuits fabricated by a commercial foundry. Since the etch consists of a single micromachining step performed on packaged and bonded dice, this technique has the potential for cost-effective prototyping and production of integrated sensors and circuits. <<ETX>>
Antibodies to fastidious faecal adenoviruses (species 40 and 41) in sera from children

Three hundred and seventy‐seven single sera from children in the United Kingdom, Hong Kong, New Zealand, Gambia, Guatemala, and Kuwait were tested for antibodies to fastidious fecal adenoviruses (species 40 and 41) by neutralisation test using a variant of Ad41 (Ad4la). All children were less than 12 years of age, and at least 41.1% of the total tested had antibodies. One hundred and fifty‐four of these sera were collected during the 1960s from London children attending day nurseries, and 54.5% had antibodies to Ad40 or Ad41. The proportion of seropositive children from an isolated Gambian village community in 1979 was similar to the proportion of seropositives in London children bled in 1979–1980.
Accuracy and Issues of the Spectroscopic Analysis of RTN Traps in Nanoscale MOSFETs

This paper investigates the limitations to the accuracy and the main issues of the spectroscopic analyses of random telegraph noise (RTN) traps in nanoscale MOSFETs. First, the impact of the major variability sources affecting decananometer MOSFET performance on both the RTN time constants and the trap depth estimation is studied as a function of the gate overdrive. Results reveal that atomistic doping and metal gate granularity broaden the statistical distribution of the RTN time constants far more than what comes from the random position of the RTN trap in the 3-D device electrostatics, contributing, in turn, to a significant reduction of the accuracy of trap spectroscopy. The accuracy is shown to improve the higher is the gate overdrive, owing to a more uniform and gate-bias-independent surface potential in the channel, with, however, the possible drawback of triggering the simultaneous trap interaction with both the channel and the gate. This simultaneous interaction is, finally, shown to critically compromise trap spectroscopy in thin-oxide devices.
Effect of zinc imprinting and replacing inorganic zinc with organic zinc on early performance of broiler chicks

&NA; The goal of this study was to determine the effects of feeding a zinc (Zn) deficient diet to broiler chicks for 96 h post‐hatch followed by feeding diets with different Zn sources and supplemental levels (5 to 21 d) on the growth performance, tissue, and excreta Zn content. At the start of the study, four hundred 20‐day‐old male broiler chicks were divided into two groups. One group was fed a corn soybean meal based diet containing 25 mg of Zn/kg (imprinting diet, ID). The second group was fed the basal diet supplemented with 40 mg of Zn/kg from Zn oxide (ZnO) (non‐imprinting diet, NID). Both groups were fed these diets for 96 h. At d 5, chicks from each group were randomly assigned to the dietary treatments consisting of the basal diet alone or the basal diet supplemented with 8 or 40 mg/kg Zn as ZnO or Zn proteinate. Main effects of post‐hatch Zn ID were observed on feed intake and G:F. ID decreased (P < 0.05) feed intake and improved (P < 0.05) the gain to feed ratio (G:F) of 14 and 21 d old chicks compared to G:F of chicks fed NID. Additionally, G:F for 14 and 21 d was improved (P < 0.05) by interaction of Zn source × level. Furthermore, at d 21 chicks fed the ID had a lower (P < 0.05) Zn content in the tibia ash and excreta, and a higher (P < 0.05) Zn content in the pancreas tissue compared to chicks fed NID. These results suggest that Zn imprinting can affect body Zn stores and early performance.
Research on saturation compensation control of Interior Permanent Magnetic(IPM) motor with wide speed operation

In this paper the mathematics model of IPM motor accounting for magnetic saturation and the effectiveness of magnetic saturation and cross-saturation on the IPM motor output characteristics and control characteristics are investigated over the entire operation range including constant torque range region and constant power region. Then a compensation control algorithm had been proposed based on above analysis. Finally the IPM motor speed control system applied the novel control method is established based on TMS320F2812 DSP chip, and the motor speed-torque output characteristics were analyzed. The experimental results verify that it can effectively improve the performance of the motor control system by using the control method proposed in this paper.
Spatial Variations and Determinants of Per Capita Household CO2 Emissions (PHCEs) in China

In China, household CO 2 emissions (HCEs) are increasing due to economic development and accelerated urbanization. This paper details the spatial variations of per capita household CO 2 emissions (PHCEs) in China and the factors impacting PHCEs using spatial statistical analysis and a spatial panel data model for the period from 1997 to 2014. Our results indicate that (1) there has been high provincial variation in rates of change across China, with some provinces’ PHCEs increasing by an order of magnitude from 1997 to 2014; (2) the Global Moran’s I of PHCEs are above 0, and the spatial differences between PHCEs are caused by the High-High cluster and Low-Low cluster in China; (3) a 1% increase of per capita income, education level, and urbanization will result in increases in PHCEs of 0.6990%, 0.0149%, and 0.0044%, respectively, whilst a 1% increase in household size will result in a 0.0496% decrease in PHCEs. There are a large number of factors impacting CO 2 emissions, while there is little specific guidance on the spatial variations and provincial characteristics of CO 2 emissions from the perspective of household consumption.
A pain consultation clinic for women.

Are specialized services useful for women? 1,2 A pilot study addressing usefulness was undertaken in 1990 at the Craniofacial Pain Research Unit of Mount Sinai Hospital, Toronto (which is affiliated with the University of Toronto). This unit is an interdisciplinary clinical research service mainly involving the departments of Neurology (Medicine), Dentistry and Psychiatry, with significant input from the departments of Nursing, Anaesthesia and Otolaryngology. About 2000 patients are seen annually in this unit, of whom 70% to 75% are women. Common presenting conditions are episodic tension headache, temperomandibular disorders, trigeminal neuralgia and atypical face pain, the last of which occurs in 10% to 15% of the unit’s population, predominantly women. Most of the patients with atypical face pain complain of severe, constant pain accompanied by sadness, poor sleep, fatigue, back pain and generalized muscle pain. The pain is frequently precipitated by dental or other procedures. Inquiry often reveals family and marital difficulties; job dissatisfaction; physical, sexual and emotional abuse; or other psychologically charged issues. Patients in one subgroup, predominantly women, experience chronic myofascial pain in the area of the temperomandibular joint and chronic tension or medication-induced headache accompanied by multiple somatic complaints. Patients in a second subgroup, also predominantly women, suffer intractable and severe facial and head pain arising from a combination of articular, myogenous and neuropathic sources. These people are severely disabled, often depressed and often addicted to one or more opiate or adjunctive pharmaceutical agents; they are the subject of a forthcoming prospective clinical trial. A third, smaller subgroup, for which the ratio of men to women is not clear, suffer more clearly defined trigeminal nerve injuries and neuropathic lesions producing severe allodynic or hyperpathic pain. Several female professionals currently work in the unit, and all patients, men and women, are now routinely referred for psychiatric input whenever appropriate. In 1990, however, the physicians and dentists performing the initial consultations for admission to the unit were all men, and they had not yet established a close working relationship with the Department of Psychiatry. Accordingly, in our capacities as psychiatrist and neurologist respectively, we decided to carry out a pilot project to see whether referring women with chronic cranial pain for psychiatric assessment would be acceptable to the patients (i.e., would they agree to go? ), whether seeing a woman professional would make it easier for such patients to speak about personal concerns and whether referral of patients for psychiatric assessment would allow the establishment of closer links between the Department of Psychiatry and the other pain specialties.
Changes in von Willebrand factor and ADAMTS13 during IVF

During IVF, circulating estradiol concentrations are strongly increased, and this may have direct effects on hemostasis. Elevated von Willebrand factor levels represent an important risk factor for arterial and venous thrombosis. ADAMTS13, also known as von Willebrand factor-cleaving protease, has an important regulatory function of von Willebrand factor but has not been studied during IVF. Blood was sampled from 31 women at maximal downregulation of estradiol synthesis using gonadotropin-releasing hormone analogues and during high-level stimulation of estradiol synthesis using follicle-stimulating hormone during the first phase of IVF. Von Willebrand factor antigen, von Willebrand factor ristocetin cofactor activity, factor VIII and ADAMTS13 antigen and activity levels in plasma were determined at the time of downregulation and at high-level stimulation. Estradiol increased from a mean of 154 pg/ml at downregulation to 5889 pg/ml at high-level stimulation (range 1620–19 500 pg/ml). Factor VIII increased from 0.96 ± 0.34 to 1.26 ± 0.41 kIU/l (P < 0.001). Von Willebrand factor antigen and activity increased from 0.75 ± 0.22 to 1.06 ± 0.40 kIU/l (P < 0.001) and from 0.83 ± 0.26 to 1.24 ± 0.48 kIU/l (P < 0.001), respectively. ADAMTS13 antigen decreased from 72.2 ± 13.5 to 67.9 ± 9.9% (P < 0.05, P = 0.01) and ADAMTS13 activity from 88.6 ± 18.3 to 80.8 ± 15.7% (P < 0.01). The increments in estradiol and factor VIII during IVF were paralleled by an increase in von Willebrand factor antigen and activity, and a decrease in circulating ADAMTS13 antigen and activity, respectively. This could in part explain why these patients have an increased risk of thrombotic events.
Skin tissue generation by laser cell printing

For the aim of ex vivo engineering of functional tissue substitutes, Laser‐assisted BioPrinting (LaBP) is under investigation for the arrangement of living cells in predefined patterns. So far three‐dimensional (3D) arrangements of single or two‐dimensional (2D) patterning of different cell types have been presented. It has been shown that cells are not harmed by the printing procedure. We now demonstrate for the first time the 3D arrangement of vital cells by LaBP as multicellular grafts analogous to native archetype and the formation of tissue by these cells. For this purpose, fibroblasts and keratinocytes embedded in collagen were printed in 3D as a simple example for skin tissue. To study cell functions and tissue formation process in 3D, different characteristics, such as cell localisation and proliferation were investigated. We further analysed the formation of adhering and gap junctions, which are fundamental for tissue morphogenesis and cohesion. In this study, it was demonstrated that LaBP is an outstanding tool for the generation of multicellular 3D constructs mimicking tissue functions. These findings are promising for the realisation of 3D in vitro models and tissue substitutes for many applications in tissue engineering. Biotechnol. Bioeng. 2012; 109:1855–1863. © 2012 Wiley Periodicals, Inc.
Depression as a predictor of mortality and hospitalization among hemodialysis patients in the United States and Europe.

BACKGROUND Depression is not uncommon among patients with end-stage renal disease (ESRD) being treated by hemodialysis. We investigated whether risk of mortality and rate of hospitalization may be predicted from physician-diagnosed depression and patients' self-reports of depressive symptoms. METHODS Data were analyzed from the Dialysis Outcomes and Practice Patterns Study (DOPPS) for randomly selected ESRD patients being treated by hemodialysis in the United States (142 facilities, 2855 patients) and five European countries (101 facilities, 2401 patients). The diagnosis of depression during the past year was abstracted from the medical records. In addition, the patients were asked to indicate how much of their time over the previous four weeks they had felt (1) "so down in the dumps that nothing could cheer you up" and (2) "downhearted and blue. " A response of "a good bit,""most," or "all" of the time were classified as depressed. RESULTS The prevalence of depression was nearly 20%. The relative risks of mortality and hospitalization among depressed (vs. non-depressed), adjusted for time on dialysis, age, race, socioeconomic status, comorbid indicators and country were, respectively: 1.23 and 1.11 for physician-diagnosed depression, 1.48 and 1.15 for the "so down in the dumps" question, and 1.35 and 1.11 for the "downhearted and blue" question (P < 0.05 for all six relative risks). These associations were not significantly different between US and European patients. CONCLUSIONS Self-reported depression by two simple questions was associated with increased risks of mortality and hospitalization for hemodialysis patients. Future research needs to assess whether early identification and treatment of depression may help to improve quality of life and survival in hemodialysis patients.
Effect of uncomplicated, presumptive influenza on the diffusing capacity of the lung.

Serial studies of pulmonary diffusing capacity for carbon monoxide were conducted during a period of as long as 20 months in 20 patients who had developed uncomplicated influenza during the winter epidemic of 1968 to 1969. In all patients, diffusing capacity initially decreased, more in women than in men. In 4, the diffusing capacity returned to more than 90 per cent of the maximal value within 10 to 12 weeks from the onset of illness; in 4, the recovery took more than 6 months. The data indicated that uncomplicated influenza can cause changes in pulmonary parenchyma or small airways associated with impairment in function.