Miracle-dz/UniFAR-FTUs huggingface dataset:
Moderate exercise, postprandial lipemia, and skeletal muscle lipoprotein lipase activity.

One mechanism by which prior exercise decreases the plasma triacylglycerol (TG) response to dietary fat may involve enhanced clearance of TG-rich lipoproteins. The purpose of the present study was to examine the influence of moderate intensity exercise on postprandial lipemia and muscle lipoprotein lipase (LPL) activity. Eight physically active, normolipidemic men aged 27.0 years (SD 4.2), body mass index 24.5 kg. m(-2) (SD 1.3), participated in 2 oral fat-tolerance tests with different preceding conditions. The afternoon before one test ( approximately 16 hours), subjects cycled for 90 minutes at 62.3% (SD 1.7%) of maximal oxygen uptake. Before the other test, subjects refrained from exercise. Samples of muscle, venous blood, and expired air were obtained in the fasted state. Subjects then consumed a high-fat meal (1.4 g fat, 1.2 g carbohydrate, 0.2 g protein, 73 kJ energy per kg body mass) before further blood and expired air samples were collected until 6 hours. The 6-hour areas under the TG concentration v time curves for plasma and for the chylomicron-rich fraction were lower (P <.05) after exercise (plasma, 7.91 [SE 1.09] v 5.72 [SE 0.47] mmol. L(-1). h; chylomicron-rich fraction, 1.98 [SE 0.51] v 0.92 [SE 0.16] mmol. L(-1). h). Muscle LPL activity was not significantly influenced by prior exercise, but the 4 subjects who had higher muscle LPL activity after exercise also had the most noticeable decreases in postprandial lipemia. The difference in lipemia between trials was inversely related to the difference in LPL activity (rho = -.79, P <.05). In the fasted state and postprandially, carbohydrate oxidation was lower after exercise (P <.05). Thus moderate exercise attenuates postprandial lipemia, possibly by altering muscle LPL activity.
Exploring health by reproductive status: an epidemiological analysis of preconception health.

BACKGROUND Recently published preconception health guidelines promote maternal health, yet adherence to those guidelines has not been documented. We hypothesized that pregnant women engaged in a healthier lifestyle than nonpregnant women, although this may vary by pregnancy intention and birth control method. METHODS We performed secondary analysis of cross-sectional data from the Behavioral Risk Factor Surveillance System (BRFSS) (2002 and 2004 datasets). The data are collected in all 50 states, the District of Columbia, Puerto Rico, the U.S. Virgin Islands, and Guam through a telephone survey of 350,000 adults annually. Subjects were a representative sample of noninstitutionalized, 18-44-year-old, fertile women (n = 66,152). Based on pregnancy risk, women were grouped into one of five categories: pregnant, intending pregnancy (IP), unintended pregnancy high risk (HR), moderate risk (MR), and low risk (LR). Logistic regression was used to estimate adjusted prevalence odds ratios (aPOR) and 95% confidence intervals (CI) for behavioral characteristics using pregnant women as the referent group. RESULTS IP, HR, MR, and LR women were more likely to drink any alcohol (aPOR 10.85, aPOR 8.39, aPOR 11.90, aPOR 11.98, respectively), binge drink (aPOR 7.07, aPOR 6.24, aPOR 7.27, aPOR 7.17, respectively), heavy drink (aPOR 6.90, aPOR 5.67, aPOR 7.48, aPOR 5.89, respectively), and smoke (aPOR 2.89, aPOR 2.69, aPOR 2.40, aPOR 2.09, respectively). Interestingly, IP, HR, MR, and LR women were more likely to engage in leisure activity (aPOR 1.37, aPOR 1.19, aPOR 1.57, aPOR 1.17, respectively). HR, MR, and LR women were less likely to consume folic acid (aPOR 0.14, aPOR 0.21, aPOR 0.29, respectively), whereas women intending a pregnancy were equally likely to consume folic acid (aPOR 0.77 CI 0.30, 2.0), although the response rate for folic acid was low. CONCLUSIONS Preconceptional health goals are not being met. Pregnancy risk, as delineated by contraceptive use, can inform interventions designed to prevent adversely exposed pregnancies.
Influence of brand and price on the decision to start a franchise store

This working paper focuses on the choice of a franchise by a potential franchisee who stars a store for the first time. The aim is to analyze the relationship between two signals - brands value and price- which have been sent by the franchisor, and the choice of a franchise. The Signaling Theory has been used to analyze this relationship. Using data panel methodology, we conclude that brands value, initial franchise fees and investment are the signals which have been taken into account by the Spanish franchisees to start a franchise store during period 2002-2008.
The effect of online and offline word-of-mouth on new product diffusion

This study investigates how the online and offline communication channels jointly influence a firm's new product diffusion. Considering the online and offline word-of-mouth effect, we compare three strategies through which a firm diffuses its product, i.e. offline diffusion strategy, online diffusion strategy and both offline and online diffusion strategy. The findings indicate that product peak sales rate and cumulative sales at peak time would be highest when managers market their products only through the online channel. However, product peak adopting time is not determined by the strategy which the manager takes, but is contingent on the relationship among the online/offline innovation effect, online/offline imitation effect and the proportion of offline consumers. Further parameter analysis provides several managerial insights.
Principles of Water Resources Allocation Founded on Full Attributes

In water resources allocation, the principles of validity, impartiality and sustainability should be kept to. But, in practical use, there are few researches conducted in this field by now as to persevere, embody and quantify these principles in operation. The authors try to discuss the problem of water resources allocation and establish the mathematical functions for the principles based on the basic theory of the three principles in this study. With quantification of the principles, the principles are measured through rational treatment. The research can offer credible reference for decision maker in water resources allocation practice.
The Effect of Characteristics and Perceived Privacy Risk of Mobile Location-based SNS on Intention to Use SoLoMo Applications

Submitted:October 28, 2014 1 Revision:December 18, 2014 Accepted:December 22, 2014 * 연세대학교 정경대학 경영학부 교수 ** 연세대학교 일반대학원 경영정보학과 석박사통합과정 In recent years, the social network service (SNS) and the location-based social network service (LBSNS) industry is expanding and the competition within the field is increasing much more. Since 2010, the full-scaled studies of SNS and LBSNS have begun. With the growth of SNS and LBSNS markets, SoLoMo (Social-Local-Mobile) is also becoming the trend for applications in different fields. However, despite the importance of SoLoMo, there have been little studies on the characteristics of SoLoMo applications. The purpose of this research is to investigate the effect of characteristics and perceived privacy risk of mobile location-based SNS on intention to use SoLoMo applications. For the purpose, we proposed a SoLoMo service acceptance model with TAM (Technology Acceptance Model) and the characteristics of SoLoMo applications. The characteristics consist of three factors, i.e. SNS, location, and mobile-related factors. This study also considered a gamification and a perceived privacy risk factor influencing on SoLoMo service usage in our proposed research model. The results of our empirical analysis using partial least squares (PLS) method show that the characteristics of SoLoMo applications including SNS, location, and mobile-related features, gamification, and perceived privacy risk have partially an effect on intention to use SoLoMo applications. Based on these results, SoLoMo-related companies will be able to increase the usage of SoLoMo services by differentiating their own strategies with these factors influencing on SoLoMo services. Keyword:SoLoMo, Social Network Service, Location-based SNS, Gamification, Perceived Privacy Risk, TAM, PLS 韓國IT서비스學會誌 第13卷 第4號 2014年 12月, pp.205-230 206 Taeksoo Shin.Won Sang Cho
Expression of ExsA in trans Confers Type III Secretion System-Dependent Cytotoxicity on Noncytotoxic Pseudomonas aeruginosa Cystic Fibrosis Isolates

ABSTRACT Twelve Pseudomonas aeruginosa cystic fibrosis isolates that are not able to exert a type III secretion system (TTSS)-dependent cytotoxicity towards phagocytes have been further studied. The strains, although possessing TTSS genes and exsA, which encodes a positive regulator of the TTSS regulon, showed no transcriptional activation of the exsCBA regulatory operon. The expression of exsA in trans restored the in vitro secretion of TTSS proteins and ex vivo cytotoxicity.
Initial Public Offerings: The Origin of Investor Recognition?

Merton (1987) argues that, if information is costly, a firm that decreases the information costs of investors can increase its investor recognition and thereby increase its value. I study a key decision that allows a firm to influence its investor recognition, namely, the initial public offering. By selling a larger number of underpriced shares, pre-IPO shareholders can decrease the information costs of IPO investors, increase investor recognition, and thereby increase the value of the shares that they retain after the IPO. My results show that greater compensation for information costs from pre-IPO shareholders to IPO investors is associated with a permanent increase in investor recognition and firm value.
Internet Privacy Research: Framework, Review and Opportunities

Increased Internet traffic and the sophistication of companies in tracking that traffic have made privacy as a critical issue in electronic commerce (e-commerce), and in turn spawned a number of research works in the literature. Despite this, what is lacking is an effort to understand the relationships among the various studies. The purpose of this paper is to consider the fields of information systems, business and marketing, and provide a framework for the research works that have dealt with three main stakeholders, namely customer, company and government, as well as the interaction arising among them. We review the literature and identify opportunities for future research.
Protein Kinase N (PKN) and PKN-Related Protein Rhophilin as Targets of Small GTPase Rho

The Rho guanosine 5′-triphosphatase (GTPase) cycles between the active guanosine triphosphate (GTP)-bound form and the inactive guanosine diphosphate-bound form and regulates cell adhesion and cytokinesis, but how it exerts these actions is unknown. The yeast two-hybrid system was used to clone a complementary DNA for a protein (designated Rhophilin) that specifically bound to GTP-Rho. The Rho-binding domain of this protein has 40 percent identity with a putative regulatory domain of a protein kinase, PKN. PKN itself bound to GTP-Rho and was activated by this binding both in vitro and in vivo. This study indicates that a serine-threonine protein kinase is a Rho effector and presents an amino acid sequence motif for binding to GTP-Rho that may be shared by a family of Rho target proteins.
[The transfer of selective serotonin reuptake inhibitors to human milk].

BACKGROUND This article presents an overview of the excretion of the SSRIs citalopram, paroxetine, fluoxetine, fluvoxamine and sertraline in breast milk. MATERIAL AND METHODS Published articles on selective serotonin reuptake inhibitors and excretion in breast milk were identified and reviewed. In addition, drug concentrations were measured in milk from eight women using paroxetine (n = 4), citalopram (n = 3) or fluvoxamine (n = 1). RESULTS Data from the literature indicate that the relative dose to the infant is lowest for fluvoxamine and sertraline, somewhat higher for paroxetine and highest for citalopram and fluoxetine. Adverse effects were reported in three of the 119 breastfed infants. Our own results show minimal excretion of fluvoxamine, small excretion of paroxetine and higher excretion of citalopram into breast milk. INTERPRETATION If treatment with a selective serotonin reuptake inhibitor is started during the postpartum period, fluoxetine should not be the first alternative. High doses of citalopram should also be used with caution. However, when the use of an SSRI is clearly indicated in a breastfeeding woman, available data generally indicate that the positive effects of breast-feeding outweigh the risks for pharmacological effects in the infant.
Sustainability of Urban Freight Transport: Retail Distribution and Local Regulations in Cities

textabstractAlthough our urbanized civilization requires freight transport in order to sustain it, urban freight transport is especially recognized for its unsustainable impacts. To reduce the unsustainable impacts of urban freight transport, many local governments develop policies that focus sometimes more on banning or restricting urban transport than on making it more sustainable. In the first part of this thesis we develop a framework to structure the urban freight transport field and to review urban fraight transport sustainability initiatives. The number of initiatives that is succesfully implemented in practice turns out te be quite low. In the review and the following analysis, we try to find the barriers for succesful implementation of the initiatives in practice. In the seond part we examine the impacts of the most commonly used local sustainability policies. Six time-window scenarios and their impacts on the economical, environmental and social sustainability are examined based on a multiple case study. Time-window regulations increase both the environmental and distribution costs. Retail chains are affected differently by time-window pressure and vehicle restrictions due to differences in their logical concept. based on an experiment we examine the effects of retailers' logical decisions in combination with local sustainability policies. Next, we examine the degree to which retailers are able te deal with problems caused by time-windows. Combining the primary and secondary distribution, i.e. factory gate pricing, results in more sustainable distribution operations for the retailer and in less sensivity towards time-window regulations.
Principle verification prototype chopper using SiC MOSFET module developed for partial boost circuit system

A new very high efficiency chopper based on partial power converter concept with 2 batteries, targeting over 99.3% in total system efficiency, was proposed. SiC-MOSFET module was applied due to fabrication of a 10 kW principle verification chopper with high frequency of 60 kHz. Circuitry operational test, efficiency measurement, rating test and temperature rise test have been completed. New advanced topology retains highest of 99.58 %, over 99.3 % over whole practical area from 1 kW to 10 kW, and over 99.0 % whole area from 1 kW to 20 kW in efficiency of high efficient energy conversion system under the frequency of 60 kHz.
On Typologies of Situated Interaction

Consideration of context raises issues of design. The complexity of these issues calls for a typological approach, in which conventional configuration of space plays a greater role. Theories of phenomenology, embodiment, and periphery underlie the argument that we must design for recurrent situations of everyday life, and that we must do so in a manner quite different from the anytime/anyplace universality so often held out as an objective for ubiquitous computing. Architecture, the more established discipline of physical context, demonstrates the importance of type to usable design. Not merely a functional classification, typology here is a generative abstraction, by which good design creates new instances from inexhaustible themes. This essay explains typology as a design philosophy, toward which its suggests possible steps forward from current developments in context-aware applications of computing.
Developing Standardised Accounting Information System (AIS) Course for Iraqi Higher Education: A Conceptual Framework

One of the challenges in global educational reform is a need tocome out with a curriculum that is capable of delivering 21st centuryknowledge to the students in all areas of studies of Higher EducationInstitutions (HEIs). This is to ensure that competent graduates areproduced from HEIs. Undoubtedly, the Iraq post-wars and economicsanctions have led to poor states of technology and education inthe country. As part of the Iraqi accounting education, accountinginformation system (AIS) course content has been affected by theIraqi circumstances, since the global trend demands a technologydrivencourse. This results in Iraq lagging behind compared toother countries, even amongst developing countries. Thus, thereis a need to determine the factors that need to be considered whiledeveloping an AIS course in Iraq in order to make it at on par withinternational standards. To assist in this process this paper proposesa conceptual framework which highlights AIS course content thatneed to be considered in Iraq.Keywords: AIS, Course, HEIs, technology-driven, conceptualframework.
ROR1 expression is not a unique marker of CLL

Recent studies have identified receptor tyrosine kinase‐like orphan receptor 1 (ROR1) on the surface of chronic lymphoid leukaemia (CLL) cells. In order to determine whether ROR1 expression is a suitable surrogate marker for the diagnosis of CLL we analysed the mRNA level of ROR1 in different types of non‐Hodgkin lymphomas (NHL), and detected elevated levels of ROR1 compared to control peripheral mononuclear cells in several entities (CLL ≥ mantle cell lymphoma (MCL) > marginal zone lymphoma (MZL) >> diffuse large B‐cell lymphoma > follicular lymphoma). ROR1 protein was expressed intensely on the cell surface of lymphoma cells with leukaemic blood count detected by three colour immunofluorescence. Our results indicate that ROR1 expression is not limited to CLL cases, but it is more prevalent in NHLs, mainly in MCL where it is expressed intensely and MZL where it is expressed moderately, suggesting a general role of ROR1 in lymphoma genesis and/or maintenance. Copyright © 2010 John Wiley & Sons, Ltd.
Disruptive Technology Reconsidered: A Critique and Research Agenda

The popular work by Clayton Christensen and colleagues on disruptive technology serves as a springboard to examine five key issues concerning the effect of technological change on firms and industries. This article challenges and integrates current theory in this domain, and raises questions to initiate new work. The discussion is organized around the following themes: the definition of disruptive technology, the predictive use of the theory of technological disruption, explaining the success of incumbents, the implications of the theory for the merits of being customer-oriented, and the merits of creating a spin-off to commercialize the disruptive technology. Examination of these themes shows the relationship of the disruptive technology work with research in a variety of related areas. Many of these links have not been made explicit before, and several of them have been misunderstood. This article is intended to encourage further research on disruptive technology and spur debate by practitioners and scholars alike.
Rapid recovery of genetic diversity of dogwhelk (Nucella lapillus L.) populations after local extinction and recolonization contradicts predictions from life‐history characteristics

The dogwhelk Nucella lapillus is a predatory marine gastropod populating North Atlantic rocky shores. As with many other gastropod species, N. lapillus was affected by tributyltin (TBT) pollution during the 1970s and 1980s, when local populations became extinct. After a partial ban on TBT in the United Kingdom in 1987, vacant sites have been recolonized. N. lapillus lacks a planktonic larval stage and is therefore expected to have limited dispersal ability. Relatively fast recolonization of some sites, however, contradicts this assumption. We compared levels of genetic diversity and genetic structuring between recolonized sites and sites that showed continuous population at three localities across the British Isles. No significant genetic effects of extinction/recolonization events were observed in SW Scotland and NE England. In SW England we observed a decrease in genetic diversity and an increase in genetic structure in recolonized populations. This last result could be an artefact, however, due to the superposition of other local factors influencing the genetic structuring of dogwhelk populations. We conclude that recolonization of vacant sites was accomplished by a relatively high number of individuals originating from several source populations (the ‘migrant‐pool’ model of recolonization), implying that movements are more widespread than expected on the basis of development mode alone. Comparison with published data on genetic structure of marine organisms with contrasted larval dispersal supports this hypothesis. Our results also stress the importance of local factors (geographical or ecological) in determining genetic structure of dogwhelk populations.
Physiological function and ecological aspects of fatty acid-amino acid conjugates in insects†

In tritrophic interactions, plants recognize herbivore-produced elicitors and release a blend of volatile compounds (VOCs), which work as chemical cues for parasitoids or predators to locate their hosts. From detection of elicitors to VOC emissions, plants utilize sophisticated systems that resemble the plant–microbe interaction system. Fatty acid–amino acid conjugates (FACs), a class of insect elicitors, resemble compounds synthesized by microbes in nature. Recent evidence suggests that the recognition of insect elicitors by an ancestral microbe-associated defense system may be the origin of tritrophic interactions mediated by FACs. Here we discuss our findings in light of how plants have customized this defense to be effective against insect herbivores, and how some insects have successfully adapted to these defenses. Graphical abstract Fatty acid–amino acid conjugates (FACs) in caterpillar regurgitant triggers herbivore-specific plant defenses.
Computer Interfaces and the “Direct-Touch” Effect: Can iPads Increase the Choice of Hedonic Food?

People are able to order food using a variety of computer devices, such as desktops, laptops, and mobile phones. Even in restaurants, patrons can place orders on computer screens. Can the interface that consumers use affect their choice of food? The authors focus on the “direct-touch” aspect of touch interfaces, whereby users can touch the screen in an interactive manner. In a series of five studies, they show that a touch interface, such as that provided by an iPad, compared with a nontouch interface, such as that of a desktop computer with a mouse, facilitates the choice of an affect-laden alternative over a cognitively superior one—what the authors call the “direct-touch effect. ” The studies provide some mediational support that the direct-touch effect is driven by the enhanced mental simulation of product interaction with the more affective choice alternative on touch interfaces. The authors also test the moderator of this effect. Using multiple product pairs as stimuli, the authors obtain consistent results, which have rich theoretical and managerial implications.
Dipole, quadripole, and octapole measurements in isolated beating heart preparations.

An experimental technique is described for measuring the equivalent multipole model for isolated beating hearts. The dipole, quadripole, and octapole moments are measured from weighted sums of 20 electrode potentials on the surface of a 6.35-cm diameter sphere. An iterative procedure is used to eliminate the effects of source eccentricity for dipolar data.