Miracle-dz/UniFAR-FTUs huggingface dataset:
An Overview of Coronaviruses: In-Silico Approach to Decipher Anti-SARS-CoV-2 Natural Products

In current study, we have focused on the outline of different coronaviruses including COVID-19, along with potential therapeutic targets of SARC-CoV-2. Moreover, experimentally evident anti-coronavirus natural molecules were subjected for <i>in silico</i> screening against M<sup>pro</sup> and RdRp of COVID-19, in order to predict effective cure agent for same.Docking analysis have revealed hit molecules namely tetra-<i>O</i>-galloyl-<i>β</i>-D-glucose (<b>2</b>) and juglanin (<b>25</b>) against main protease, in reference of N3 molecule (docking score = -5.95 Kcal/mol), while glycyrrhizin (<b>1</b>) and tetra-<i>O</i>-galloyl-β-D-glucose (<b>2</b>) are good against RdRp in reference of Remdesivir (docking score = -4.23 Kcal/mol). <i>In-silico</i> parameter revealed three lead compounds i.e. glycyrrhizin (<b>1</b>), tetra-<i>O</i>-galloyl-β-D-glucose (<b>2</b>) and juglanin (<b>25</b>) which can be seen as hopeful molecule for COVID-19 treatment in upcoming time. Overall review lesson is to develop a specific and effective drug molecule against the current crisis i.e. COVID-19 derived from natural source. <p></p> <br>
Trends in Scandinavian Cell Toxicology

Over a period of two years the Scandinavian Society for Cell Toxicology* has met three times (on 21 October 1983 and 6–7 June 1984 in Uppsala, Sweden, and on 6–7 September 1985 in Roskilde, Denmark), to present research advances in cell toxicology and to discuss the effects of xenobiotics in isolated and cultured cells. The first part of this report represents a summary of these discussions. In the second part, some of the individual research reports presented by the participating members are summarised. The purpose is to give a review of problems currently dealt with in Scandinavian laboratories associated with the Society for Cell Toxicology.
An Empirical Assessment of Digital Library Service: Perspective of DeLone and McLean Information System Success Model

Digital book information services have gradually been valued and relied on. Users can use computers to obtain the required information anytime, anywhere, greatly improving the convenience of reading and research. The purpose of this study is to analyze the current use of Digital Library Service by domestic university students, and to explore the influencing factors for the use of Digital Library Service by Chinese college students based on the theoretical framework of the DeLone and McLean Information System Success Model. This study first explores the importance of Digital Library Service in the field of university education and the implications and goals of the school administration system. Next, a questionnaire for this research was prepared based on the Information System Success Model framework, and a questionnaire survey was conducted for college students using Digital Library Service in China. Finally, the statistics and analysis of the recycling questionnaire were conducted. The analysis results of this study found that information quality and service quality have a positive and significant impact on satisfaction. In addition, information quality and service quality have an indirect influence on the continued use of Digital Library Service through satisfaction. However, system quality did not have a significant impact on the Digital Library Service. Based on the above conclusions, the researchers put forward suggestions for education administrative agencies, school units and future researchers, with a view to providing references for education administrators, university staff and related research.
RFID Utilization through Supply Chain Management and Logistics Performance

This research aimed to study the adoption of RFID (Radio Frequency Identification) in the operation of automotive parts industry in Thailand to increase the potential and effectiveness in supply chain and logistics management. The sample groups were 99 manufacturing firms in automotive parts industry in Thailand. The questionnaire respondents were IT leaders or those users related to RFID system. The data were gathered and a structure equation model was placed here for the testing model. The research result found that paying attention to RFID technology on the aspect of Supply chain management could help the organization to gain competitive advantages and save costs of inventory management. RFID using could also reduce the problems of errors in inventory counting and led to more transparency of inventory. Besides, paying attention to RFID technology usage also led to the efficiency in transportation because the organization would be able to follow up the transportation processes and checking the route of automotive parts.
The Physiological Reaction to Hot Stress and Screening of Hot Tolerance Index in Cucumber

The physiological reaction at germination stage and four leaf stage of three cucumber cultivars with different hot tolerance was studied in this experiment,and hot tolerance assessment index were screened.The results showed that the elongation of radicle and growth of lateral roots were quickest at 38℃ condition,inhibited at 42℃ and completely inhibited at 45℃. The radicle length stressed at 38℃ for 60～72 h could be taken as one of the hot tolerance assessment indexes. Stressed at 42℃ for 36 h,the electric conductivity percentage and soluble protein content could both reflect the difference of hot tolerance among cucumber cultivars.Unit activity and specific activity of SOD after being stressed at 38℃ for 36 h are consistent to hot tolerance of cucumber cultivars,and could be taken as the hot tolerance assessment index of cucumber.
Comparative Evaluation of the Inhibitory Potential of Synthetic N-Heterocycles, Cu/Fe3O4@SiO2 Nanocomposites and Some Natural Products against Non-Resistant and Antibiotic-Resistant Acinetobacter baumannii

Background: Acinetobacter baumannii is a common infectious agent in hospitals. New antimicrobial agents are identified and prepared to combat these bacterial pathogens. In this context, the blocking potentials of a series of synthesized N-heterocyclic compounds, Cu/Fe3O4@SiO2 nanocomposites, glycine, poly-L-lysine, nisin and hydroalcoholic extracts of Trachyspermum ammi, Curcuma longa and green tea catechins were evaluated against non-resistant and multidrug-resistant strains of A. baumannii. Methods: Solutions of heterocyclic derivatives and hydroalcoholic extracts of Trachyspermum ammi, Curcuma longa and green tea catechins were prepared at initial concentration of 10240 μg ml-1 in 10% DMSO. Other compounds were dissolved in water at the same concentrations. Their in vitro inhibitory activity was assessed by determination of IZD, MIC and MBC values. Results: Glycine, poly-L-lysine, nisin, Curcuma longa and green tea catechins extracts, and thiazoles 3a, 3d and 3f were ineffective at their initial concentrations. Heterocyclic derivatives 7a-f, 3c, 3e and 3h, Cu/Fe3O4@SiO2 nanocomposites and Trachyspermum ammi extract could block the growth of bacterial strains with IZDs (7.40-15.51 mm), MICs (32-1024 µg ml-1) and MBCs (128-2048 µg ml-1). Conclusion: Among synthetic chemicals and natural products, the best antimicrobial effects were recorded with (E)-2-(5-acetyl-4-methylthiazol-2-yl)-2-(thiazolidin-2-ylidene)acetonitrile (7b) and the extract of Trachyspermum ammi. It is imperative that their toxic and histopathologic effects were assessed in future researches. It is predicted that the essential oil of Trachyspermum ammi will improve its antibacterial activities.
The Emergence of the Next-Generation Vaccines

Introduction Vaccination is a medical technique that was first scientifically experimented by the physician Edward Jenner in the 18th century [1]. At that time, smallpox, a disease of viral origin, killed those infected and disfigured the survivors. Edward Jenner observed that farmers did not contract smallpox. However, they were often infected with vaccinia, a virus that induces a disease in cattle similar to smallpox but is beguiling to humans. E. Jenner hypothesizes that inoculating the contents of a vaccinia pustule taken from a female farmer would induce an immune response in humans that would protect them from subsequent infection by viruses similar to vaccinia such as the smallpox virus. He therefore carried out this experiment on a child and then voluntarily infected him with smallpox. As hoped, the child did not contract smallpox [2]. This discovery has been a breakthrough in science and became known as "vaccination".
Three new species of orchids (Orchidaceae) from Vietnam.

Three new orchid species are described from Vietnam as a new for science. They are-Cheirostylis cristata (related to C. bipunctata and C. chinensis), Didymoplexiella denticulata (related to D. ornata and D. siamensis) and Habenaria luceana (similar superficially to H. geniculata, H. ecalcarata, H. malintana and H. parageniculata, but having rather isolated taxonomic position). Detailed description, illustrations, data on flowering time, ecology and distribution are provided for each recognized species.
Evaluation of critical organ dosimetry with focus on heart exposure in supine versus prone patient positioning for breast irradiation

Breast cancer (Ca) remains to be the most frequent cancer among females and a leading cause of cancer associated mortality worldwide. Main modalities for management of breast Ca include surgery, Radiation Therapy (RT), and systemic treatments. Diagnosis at earlier stages of breast Ca is increasing with rigorous utilization of screening and raised public awareness. Improvements in therapy contribute to longer life expectancies for patients with breast Ca. In this context, adverse radiation effects are being a more pronounced aspect of breast Ca management recently.
The role of the natural hedge in organic farming – an adoption barrier?

The market for organic agriculture in Germany and other parts of the world has been substantially growing in the past. This raises interest of policymakers and economists in the conversion decision from conventional to organic agriculture. As one major effect of the difference in production methods between conventional and organic agriculture is the assumedly higher production risk in organic agriculture this seems to be a major determinant for the conversion decision of risk averse farmers. Natural hedge, i.e. the priceyield correlation of a crop, has been shown to be a natural risk management tool. The role of natural hedge in the conversion decision has though not explicitly been investigated yet. Using a net present value investment model and means of data simulation this research finds that natural hedge has an effect on the mean and variance of outcomes, and therefore on the conversion decision. Conversion preferences for wheat, barley, rye, potatoes, maize, field beans and sugar beets for the province of Bavaria in Germany are assessed. Assuming different levels of risk aversion of farmers one finds for the given data that a more positive (weaker) natural hedge makes cropping options more attractive. Addressing especially farmers downside risks with the introduction of a revenue insurance, results indicate that the introduction of revenue insurance for organic farming makes conversion more attractive. The more positive the natural hedge is, the greater is the possible effect of introducing insurance. Analysing natural hedge for Germany on a national and a provincial level, results point towards a more positive natural hedge for organic than for conventional crops. Given theoretical results natural hedge in Germany therefore favours conversion and makes the introduction of revenue insurance for organic farmers comparably efficient. A major obstacle in the analysis was scarce availability of data on organic agriculture. Results should therefore rather be interpreted qualitatively than quantitatively.
Working Paper: Concepts and Measures of Agency, Empowerment, and Related Issues

This paper explores the idea of empowerment and related concepts in the context of global development. It provides an overview of concepts, examples of previous measurements, and an evaluation of how effective various types of indicators have been. We hope to provide a resource that can be of use when developing surveys and other methods to assess changes in empowerment, agency, and the like. The purpose of this paper is to note promising avenues of research worth pursuing, and to suggest improvements for indicators currently in use.
Capital Market: Opportunities and Challenges

DOI: 10.21276/sjebm.2017. 4.10. 10 Abstract: Investment Corporation of Bangladesh (ICB) is one of the renowned investment banks in Bangladesh. As an investment bank, ICB has been performing its merchandising and financial assistance operations since its inception. From directly participating in equity to superintending the issue of debentures, bonds, mutual funds, etc., all are within the activities of the ICB. That is why the principal objective of the study is to examine the role of ICB in the capital market development and to explore its opportunities and challenges. The researchers have used the documents of ICB and the capital market of Bangladesh to evaluate the role of ICB in capital market development. Both qualitative and quantitative interpretations were needed for the present study. The present study has exclusively used those methods by compiling the data of very critical and eventful ten years (2001-2011) of DSE, CSE, ICB and other related financial organizations. After collecting data, the researchers edited the data and used some statistical forms according to their suitability and necessity of the study. From the study findings, it is found that the paid up capital has been steadily rising. From around the year 2006, ICB has been performing much better as seen from its net profits exceeding the paidup capital. The capital market in Bangladesh is still at a developing stage. The average size of companies in Bangladesh is minuscule compared to those of other countries. But, there was a steady progress in the capital market in the past due mainly to the government‟s continuous efforts of developing a sound securities market. As a result, there had been ongoing development of the capital market over the years. At the end of 2007, there were 350 securities listed on the Dhaka Stock Exchange (DSE) with a market capitalization of US$ 10.82 billion. The study suggests that with the increase of income and net profit, market capitalization will increase because the estimation of total income and net profit are positive. If the performance of ICB improves continuously, it will help the growth of the Bangladeshi capital market to a great extent.
Studies on the Degradation of the mycotoxin Patulin in Blood Untersuchungen zum Patulinabbau im Blut

The mycotoxin patulin was quantified in blood by the recently developed stable isotope dilution assay (SIDA) using [C2]-patulin as the internal standard. The application of SIDA revealed a patulin content less than 200 ng/mL in the serum of a volunteer, whose blood was drawn shortly after consumption of a juice containing 50 μg/L patulin. Further in-vitro experiments revealed a rapid degradation of patulin when added to blood. It was concluded, therefore, that even high natural occuring concentrations of patulin in foods are quickly degraded before reaching other tissues than the gastro intestinal tract. The degradation of patulin was attributed to its reaction with glutathione, as several glutathion-patulin adducts were detected in blood by LCMS.
Schemes with Well controlled Dissipation (WCD) I: Non-classical shock waves

We consider the approximation of entropy solutions to nonlinear hyperbolic conservation laws, in the regime that small–scale effects drive the dynamics of shock waves in these solutions. We introduce and analyze a new class of numerical methods, referred to as the schemes with well-controled dissipation (WCD), which approximate entropy solutions with high–accuracy and can capture small scale dependent shock waves of arbitrary strength. Following earlier work by LeFloch and collaborators, we rely on the equivalent equation associated with a finite difference scheme which provides us with the proper tool in order to ensure that small-scale dependent shock waves are computed accurately. Examples involving nonclassical shocks for cubic conservation laws, the nonlinear elasticity system, and a reduced model of magnetohydrodynamics are investigated with our approach.
INTERNATIONAL TECHNOLOGY DIFFUSION AND PRODUCTIVITY CHANGE IN THE TURKISH MANUFACTURING SECTOR*

Most new technologies are created in developed countries. In developing countries, contacts with the outside world, research and development (R&D), human capital, and technology diffusion play important roles in increasing innovation and productivity. Using panel data from manufacturing sectors from 2009 to 2014, this study examines the impact of various channels of technology diffusion, R&D, and human capital on labour productivity change in Turkey. According to the estimation results, the technology gap has had a positive effect on productivity change. This suggests a rapid adaptation to technology, and it may be a sign of future convergence with the technological frontier. Export intensity, improves technology transfer rate. Increase in export intensity is found to increase productivity change for the following year; and, increase in import penetration on productivity change is found to be positive in the current year and in the subsequent years. The impacts of foreign direct investments (FDI), tangible investments, R&D intensity, and human capital are found to be insignificant, while the impact of interaction of human capital with the technology gap is negative and significant. It is also found that increases in the market concentration rate, the Herfindahl-Hirschman Index (HHI), results in more rapid increases in productivity.
The effective factors on creation of foundation for organizational entrepreneurship in Port and Maritime General Organization of Guilan Province

The present survey is aiming to analyze the effect of different factors (organizational characteristics ,individual characteristics , environmental changes , basis factors ) for creation of entrepreneur foundation of organization using Kratko Model and colleagues in PMO of Guilan Province . so to recognize the entrepreneur foundation of organization. The methodology considering the type of survey is applied – descriptive . and the sample population are the all employees of PMO of Guilan province which were measured according to Cochran sample 160 and were elected randomly . the tool for measurement and evaluation was questionnaire and for final evaluation of the questionnaire the Alpha test of Cronbach was used . also the descriptive part of the indexes of the survey were evaluated by advice of the honorable instructors . for analyzing the relationships the correlation ratio of Gama was used . and also for determining the power of effect of the independent variables on dependent variables of the regression test and analyzing the path was used . according to results and regression analysis of multivariable and the diagram of analyzing the path the foundation factors by correlation of 0.568 and organizational characteristics with correlation of 0.172 and with out mediator have the highest effect on the factors creating the organizational entrepreneur foundation . also the highest positive correlation was between environmental changes variables and individual characteristics with 0.397 of positive correlation.
True Cost of Food-G20 Insights

Modern food systems, though fundamental to human life, generate heavy costs to the environment and public health. These costs transcend borders and generations; therefore, they require international governmental action. We call on the G20 to lead action on this problem by (1) issuing a mandate to international organizations to develop a harmonized approach to measure the social cost of food, (2) coordinating international reform of current harmful policies, especially subsidies linked to the emission of greenhouse gasses or a nutritionally imbalanced food supply, that contribute to costs, and (3) setting an agenda to repurpose government resources previously used on harmful policies for reducing the costs remaining after reform of current policies through beneficial policies, such as agricultural R&D for sustainability, payment for ecosystem services, and food safety initiatives.
Evaluation of newer insecticides against chilli aphids and their effect on natural enemies

The cotton aphid, Aphis gossypii (Glover) and the peach green aphid, Myzus persicae (Sulzer) are commonly found infesting chillies. Small, ovate, soft greenish brown sluggish nymphs and adults are found in large colonies on the under surface of leaves and growing shoots of plants, sucking the cell sap. The aphids also secrete honey dew on which black sooty mould develops covering the leaves and twigs. This black coating hinders the photosynthetic activity of the plant causing further retardation in growth and fruiting capacity of the plant (Butani, 1976). Chilli is a crop subjected to scheduled application of insecticides and acaricides. The pesticidal sprays have become a threat to chilli ecosystem causing resurgence of pest and threat to natural enemy fauna. Pesticide residues in chilli are of great concern from the point of view of domestic consumption and export as well. The risk of using chemical insecticides in the management strategies can be reduced by incorporating safer molecules of chemicals so that the pest could be managed with least problems to the natural enemy fauna and least residues in edible part. The aim of study was to identify the biorational insecticidal molecule that is effective in managing chilli aphids and to prove the safety of these insecticide molecules to its predators.
Supplemental Material : “Classes of critical avalanche dynamics in complex networks.”

Filippo Radicchi, Claudio Castellano, Alessandro Flammini, Miguel A. Muñoz, and Daniele Notarmuzi Center for Complex Networks and Systems Research, Luddy School of Informatics, Computing, and Engineering, Indiana University, Bloomington, Indiana 47408, USA∗ Istituto dei Sistemi Complessi (ISC-CNR), Via dei Taurini 19, I-00185 Roma, Italy Departamento de Electromagnetismo y F́ısica de la Materia e Instituto Carlos I de F́ısica Teórica y Computacional. Facultad de Ciencias. Universidad de Granada. E-18071, Granada, Spain
On the design of consequential ranking algorithms

Ranking models are typically designed to optimize some measure of immediate utility to the users. As a result, they have been unable to anticipate an increasing number of undesirable long-term consequences of their proposed rankings, from fueling the spread of misin-formation and increasing polarization to degrading social discourse. Can we design ranking models that anticipate the consequences of their proposed rankings and are able to avoid the undesirable ones? In this paper, we ﬁrst introduce a joint representation of rankings and user dynamics using Markov decision processes. Then, we show that this representation greatly simpliﬁes the construction of consequential ranking models that trade off the immediate utility and the long-term welfare. In particular, we can obtain optimal consequential rankings by applying weighted sampling on the rankings provided by models that maximize measures of immediate utility. However, in practice, such a strategy may be inefﬁcient and impractical, specially in high dimensional scenarios. To overcome this, we introduce an efﬁcient gradient-based algorithm to learn parameterized consequential ranking models that effectively approximate optimal ones. We illustrate our methodology using synthetic and real data gathered from Reddit and show that our consequential rankings may mitigate the spread of misinformation and improve the ci-vility of online discussions.