Miracle-dz/UniFAR-FTUs huggingface dataset:
Inhibitory Properties of Phenolic Compounds Against Enzymes Linked with Human Diseases

Some drugs currently used are inhibitors of enzymes involved in mediating many disease processes. Concerns over the toxicity and side effects of synthetic enzyme inhibitors have led to a search for new safe and effective inhibitors particularly from natural sources. Owing to their wide range of biological effects, plant phenolic compounds are one of the most studied families of natural products. This chapter aims to provide an overview of the potential of phenolic compounds as enzyme inhibitors. Extensive research has been conducted to study the enzyme inhibitory capacity of many phenolic compounds against several enzymes linked with important human conditions. Investigations conducted are mainly focused on the inhibition of angiotensin I-converting enzyme, α-amylase and α-glucosidase, lipase, cholinesterases, proinflammatory enzymes (cyclooxygenases and 5-lipoxygenase) and tyrosinase, which are related with hypertension, type II diabetes, obesity, Alzheimer’s diseases, inflammation and skin hyperpigmentation, respectively. Overall, among phenolics, flavonoids are probably those with great capacity to inhibit the activity of the enzymes revised. Several studies demonstrated the potent antioxidant and anti-inflammatory properties of flavonoids, which highlight the therapeutic poten - tial of these compounds. Although our literature survey showed that a huge number of phenolic compounds have been studied and there are some promising compounds depending on the enzyme, more in vivo tests and subsequent steps to be a drug candidate are required before therapeutic application.
Grasses as invasive alien plants in South Africa

7that alien grasses can transform ecosystems. At present only five grass species, all large conspicuous perennials, are declared weeds in South Africa. 8 However, perennials and annuals are equally represented in the alien grass flora. The annuals, largely of European origin, are widespread and sometimes abundant in winter rainfall and arid parts of southern Africa, whereas the perennial species have successfully invaded both winter and summer rainfall regions, particularly in wetlands and riparian areas. Most alien grass species are too poorly known to evaluate their ecological and economic impact or to recommend control measures. This preliminary review of the processes and influences of perennial and annual grass invasions seeks to address this gap. Because of the dearth of local research on this topic, information is largely drawn from studies of invasive behaviour by the same (or related) grass species in Australia and North America.
FPGA-based Regenerative Electronic Systems in the Spacecrafts

In article results of research of ways hardwaresoftware creation of the regenerative electronic systems based on application FPGA technologies with dynamic reconfiguration are presented. These systems are offered to be used in the modern spacecraft’s onboard fault-tolerant equipment. Several possible options of realization of the regenerative electronic systems capable to partially imitate processes of biological regeneration due to low-level redundancy of the configurable logic blocks are presented. The main technical and methodological difficulties arising at creation of spacecraft’s onboard regenerative electronic systems are shown. 
How Would you Like Your Packets Delivered? An SDN-Enabled Open Platform for QoS Routing

Traditional Internet routing is simple, scalable and robust, but cannot provide perfect QoS support due to the current completely distributed hop-by-hop routing architecture. Software defined networking (SDN) opens up the door to traffic engineering innovation and makes possible QoS routing with a broader picture of overall network resources. We further argue that SDN can provide more opportunity for the network users to make their own routing selections with network programmability. In this paper, we propose OpenMCR, a general framework for network users to make their own choice of routing given various requirements. OpenMCR provides routing subject to several additive QoS constraints, which is NP-hard when the number of constraints is two or more. By composing various necessary conditions with different path extension schemes, our platform can customize routing solutions for each network user based on their own requirements. Through experiments in an SDN emulated environment, we evaluate multiple aspects of OpenMCR, demonstrate its effectiveness compared with several baselines and validate our theoretical analysis.
Decision Support System for Water and Environmental Resources in the Connecticut River Basin

AbstractThis paper describes the development and application of a reservoir management decision support system for evaluating floodplain benefits and socioeconomic trade-offs of reservoir management alternatives in the Connecticut River watershed. The decision support system is composed of a reservoir system simulation model, an ecological model, and two river hydraulics models. The reservoir model simulated current operations at 73 reservoirs and flows at locations of interest in the Connecticut River watershed. Regulated flows from the reservoir model were compared with unregulated flows, both statistically and spatially, for a suite of environmental flow metrics based on inundation patterns related to floodplain vegetation communities. Analyses demonstrate use of the decision support system and show how its use illuminates (1) trends in existing hydrologic alteration for the Connecticut River mainstem and one of its tributaries, the Farmington River, and (2) management scenarios that might have ecologi.
Density estimation using inverse and reciprocal inverse Gaussian kernels

This paper introduces two new nonparametric estimators for probability density functions which have support on the non-negative real line. These kernel estimators are based on some inverse Gaussian (IG) and reciprocal inverse Gaussian (RIG) probability density functions used as kernels. We show that they share the same properties as those of gamma kernel estimators: they are free of boundary bias, always non-negative and achieve the optimal rate of convergence for the mean integrated squared error (MISE). Monte Carlo results concerning finite sample properties are reported for different distributions and sample sizes.
Dynamic Output Feedback Compensation Control for Discrete Closed-Loop Nonlinear System with Multiple Time-Delays

This paper addresses the dynamic output feedback control problem for a class of discrete system with uncertainties and multiple time-delays. First, the system is decomposed into two subsystems based on the output matrix and input control matrix. Secondly, a dynamic compensator is employed for the first subsystem, and then, given the multiple uncertainties, the output feedback controller is designed based on the second subsystem and the dynamic compensator. Thirdly, by choosing the Lyapunov-Krasovskii function, it can be seen that the developed controller makes the closed-loop system convergent to an adjustable region, which can be rendered arbitrary small by adjusting design parameters. Compared with the previous researches, the proposed controller is not only smooth and memoryless, but also only dependent on the system output. Furthermore, with the given dynamic compensator, the controller design conditions are relaxed, while the approach is extended to the conventional nonlinear system. Finally, numerical example is given to illustrate the effectiveness of the theoretical results.
Readout-power heating and hysteretic switching between thermal quasiparticle states in kinetic inductance detectors

A model is presented for readout-power heating in kinetic inductance detectors. It is shown that the power dissipated by the readout signal can cause the temperature of the quasiparticle system in the superconducting resonator to switch between well-defined states. At low readout powers, only a single solution to the heat balance equation exists, and the resonance curve merely distorts as the readout power is increased. At high readout powers, three states exist, two of which are stable, and the resonance curve shows hysteretic switching. The power threshold for switching depends on the geometry and material used but is typically around −70 dBm for Aluminum resonators. A comprehensive set of simulations is reported, and a detailed account of the switching process is given. Experimental results are also shown, which are in strong qualitative agreement with the simulations. The general features of the model are independent of the precise cooling function, and are even applicable for resonators on suspended, thermally isolated, dielectric membranes, where an increase in quasiparticle lifetime is expected. We discuss various extensions to the technique, including the possibility of recovering the cooling function from large-signal measurements of the resonance curve.
Sex ratio adjustment in birds

Abstract In a number of bird species, the sex ratio of the broods is not random, instead it is related to parental quality and environmental conditions. Several hypotheses have been proposed to explain this phenomenon, the so called sex ratio adjustment. According to these hypotheses, sex ratio adjustment is expected to evolve when the fitness benefit an offspring confers to the parents changes with ecological or social factors in a sex-specific way. Though many correlative and experimental studies support these hypotheses, there are still unresolved problems. In our paper, we provide details on the hypotheses related to sex ratio adjustment and explanations for the differences observed in sex ratio patterns between populations and years. Finally, we discuss the importance of sex ratio adjustment for species conservation. Összefoglalás Számos madárfajnál kimutatták, hogy a fészekaljak ivararánya nem véletlenszerű, hanem a szülői vagy környezeti tulajdonságok függvényében változik. Az ivararány-manipuláció néven ismert jelenség magyarázatára számos elméletet dolgoztak ki. Ezek szerint az ivararány-manipuláció azokban az esetekben alakulhat ki az evolúció során, amikor a hím és tojó utódok túlélése, várható szaporodási sikere vagy felnevelési költsége eltér. Bár számos korrelatív és kísérletes vizsgálat támogatja ezeket a hipotéziseket, vannak még az ivararány-manipulációval kapcsolatban megoldatlan kérdések. Cikkünkben részletesen tárgyaljuk az ivararány-manipulációt magyarázó elméleteket, valamint az ivararány-mintázatok populációk és vizsgálati évek közötti eltéréseinek lehetséges okait. Kitérünk a jelenség természetvédelmi jelentőségére is.
A Computational Algorithm for Dynamic Regrasping Using Non-dexterous Robotic End-effectors

The presented research addresses the problem of regrasping an object. That is, to switch between grasp configurations according to designated tasks to be done. The state of the art in regrasping methods is mostly quasi-static motions which requires high dexterous end-effectors. This research intends to approach the regrasping problem with dynamic manipulations. That is, utilize the dynamics of the robotic arm to perform the regrasping operation while grasping the object with a simple non-dexterous endeffector. As will be discussed further, in this research we intend to perform the dynamic regrasping with two strategies, one is the in-hand spinningand the other is the mid-air flipping. Currently, an algorithm for motion planning of the in-hand spinning strategy was developed. While approaching the problem and its constraints, a method for dynamic motion planning was needed. We surveyed methods which could enable planning under kinematic and dynamic constraints and incorporate rendevouze planning of two systems (arm and manipulated object). First, the RRT (LaValle and Kuffner, 1999) planning method was examined. However, the RRT method has disadvantage in dynamic planning with time constraint. Therefore, we have modified the RRT and presented the Time-Based RRT method (Sintov and Shapiro, 2014b) which could plan a dynamic motion with a time constraint and use it for rendevouze planning. However, this method was not fully compatible for our needs, and we started developing our own dynamic planning algorithm. The Semi-Stochastic Kinodynamic Planning (SKIP) algorithm was developed. It was originally developed for the regrasping problem, but is given as a generic planning algorithm for any fully actuated dynamic system. A journal paper of the full algorithm was recently submitted (Sintov and Shapiro,
Productive response of lambs fed with fresh or dehydrated spineless cactus (Opuntia ficus-indica L.)

The objective of this study was to evaluate the effect of cactus (Opuntia ficus–indica L.) supplementation on lamb animal performance, during a 11–week period. For this purpose, 27 male lambs of commercial crossbreeds were used, with initial live weight mean of 21.4±3.8 kg. They were distributed homogeneously into three groups of nine each, and then randomly assigned to each of the following treatments: (T1) control diet, (2) diet with 17% (dry matter basis) of dehydrated cactus, and (3) diet with 17% (dry matter basis) of fresh cactus. Digestibility in situ of the diet, dry matter intake (DMI), daily gain weight (DGW), feeding conversion (FC) and efficiency (FE), back fat, hot and cold carcass yield, biological hot and cold carcass yield, and carcass pH at slaughtering and 24h post mortem, were evaluated. A completely random design using Proc GLM was used, and when statistical differences were observed, a mean comparison was done using the Tukey test. There were significant differences (P≤0.001) on DM digestibility, with higher value (42.0%) on the control diet during the first 6 hours of incubation, but after 48 hours, the highest digestibility (88.6%) was on the fresh cactus diet. There were not significant differences (P>0.05) between treatments on animal performance, except on back fat, being higher (P<0.001) on dehydrated (4.1 mm) and fresh (3.3 mm) diets, compared to the control one (7.8 mm). The means for hot and cold carcass yield, biological hot and cold carcass yield, and carcass pH at slaughtering and 24h post mortem were 50.6%, 47.0%, 55.4%, 49.5%, 6.6% and 5.8%, respectively. Diet including cactus had similar effect on productive parameters than that of the commercial one, which makes it a viable feeding strategy, and from the economical point of view, could be attractive to the farmer, since the cactus is a plant that grows over the year. However, there is a need of doing more research to confirm these results, not only on fattening lambs, but also on the different animal life stages, considering different levels of cactus, and working on different animal breed and species.
Do Financial Constraints Hamper Environmental Innovation Diffusion? An Agent-Based Approach

We develop a model that combines evolutionary economics concepts and methods with environmental economics concerns. The model is populated by consumers, heterogeneous firms, and a financial sector and is used to investigate the dynamic interactions between the demand and supply side, and the role played by binding financial constraints, in the diffusion of environmental innovations. The aim of the model is to understand how environmental goals can be effectively promoted and achieved in presence of a financial sector whose lending attitude is guided by long-termism rather than shorttermism. We show that financial constraints act as a deterring barrier and affect firms’ innovation strategies as well as the evolution of technological paradigms. When financial constraints are less binding, firms do not perceive hindrances to the adoption of eco-innovation and, as a result, the presence of the average green technology in the market increases.
Macronutrients in tree stems and foliage: a comparative study of six temperate forest species planted at the same sites

Common European tree species ( oak, ash, beech, birch, lime and spruce) planted in adjacent stands on six sites were compared in terms of macronutrient concentrations in foliar and stem wood ( including bark) biomass. The nutrient concentrations in both biomass compartments were much more dependent on species than on site although soil conditions differed between the sites. Differences between species regarding stem wood nutrient concentrations only partly corresponded to the differences in species foliage. The concentrations in spruce were considerably lower than in deciduous species, except P in foliage, and Ca in both stem wood and foliar biomass. Differences were also observed between the deciduous species both regarding foliar and stem wood nutrient concentrations. The differences should be considered when modelling nutrient circulation in forest stands and when evaluating the long-term sustainability of forest management. (Less)
Leadership Styles and the Moral Choice of Internal Auditors

Internal auditors’ performance largely depends on their moral decisions when faced with ethical dilemmas. This study explores the impacts of different leadership styles on internal auditors’ moral choice using ERG theory and Path-goal theory. The findings of the survey demonstrated support for both theories. Regression analysis revealed that a sample of West Australian internal auditors were motivated by growth needs and the motivation was enhanced if the leader took a Standardachievement-oriented approach. Gender appeared as an important predictor and female respondents in the survey were younger and less experienced than their male counterparts and appeared less motivated towards moral choice.
Determinants of the success of international assignees as knowledge transferors: a theoretical framework

Drawing on previous work in the knowledge management literature, this article develops a conceptual framework to analyse the cause and effects of international assignments as a knowledge transfer mechanism. In examining the characteristics of knowledge transferred within multinational companies (MNCs) the use of international assignees is explained and justified. The article also identifies the factors influencing the success of international assignees as knowledge transferors. It is argued that, in addition to the specific characteristics of the knowledge involved, transfer success will be affected by three sets of human-related factors: abilities and motivation of international staff; abilities and motivation of local employees; and the relationship between local and international staff. The article concludes by discussing some management initiatives helping to trigger the human-related factors.
Effects of Phytomedicines Evaluated Using Omics Approaches

The advent of the omics area has created new research systems, including genomics, proteomics, metabolomics, as well as the associated bio-informatics science, and databases. At the same time, progress in traditional western medical research has reached a bottleneck, as single compound drugs are costly to create, synthesize, or engineer. If we are to see real and sustained progress in research, we must find approaches to utilize traditional remedies to develop advanced medicines. Instrumental systems for transcriptome, including the microarray of different messenger RNA, microRNA and other non-gene sequence-related RNA products, have already been developed; functional genomics studies using these systems have been remarkably successful. However, the candidate genes involved in specific functions often need further verifications for revealing their roles in the signal pathways. The difficulty may also arise from the high variety and seemingly unrelated responsive genes and complex signaling or regulatory systems involved. Proteomic analysis has its disadvantages, although two-dimensional (2-D) gels can display viable candidate proteins for study. Up to two thousand proteins of biological systems can often be analyzed in sensitive 2-D gel systems. There are other proteins, such as cytokines or chemokines of most leukocyte cells are expressed at relatively low levels, and often are not detectable by 2-D gels. More sensitive methods, such as LC/MS and other fractionation systems, need to be used for such cases. Metabolomics faces an even greater challenge: a 2-D or one run display of the components of a metabolome has not been defined and cannot be systematically evaluated. Therefore, sequential analyses, e.g. the LC/MS followed by NMR, were developed to address the “overall” or more comprehensive picture of metabolomes. Several phyto-medicinal studies, including some in traditional Chinese herbal medicine (TCM), have been considered as metabolome investigations. New strategies employing omics approaches may be especially useful for phytomedicinal research, as conventional phytomedicines often employ multiple components and they often are believed to interact with multiple molecular targets related to cellular and physiological (e.g., immunemodulatory) effects. In order to successfully evaluate the effects of phytomedicines, various omics approaches are being systematically combined. New computational and cross-
A CLOUD-BASED ARCHITECTURE FOR SMART VIDEO SURVEILLANCE

Abstract. Turning a city into a smart city has attracted considerable attention. A smart city can be seen as a city that uses digital technology not only to improve the quality of people’s life, but also, to have a positive impact in the environment and, at the same time, offer efficient and easy-to-use services. A fundamental aspect to be considered in a smart city is people’s safety and welfare, therefore, having a good security system becomes a necessity, because it allows us to detect and identify potential risk situations, and then take appropriate decisions to help people or even prevent criminal acts. In this paper we present an architecture for automated video surveillance based on the cloud computing schema capable of acquiring a video stream from a set of cameras connected to the network, process that information, detect, label and highlight security-relevant events automatically, store the information and provide situational awareness in order to minimize response time to take the appropriate action.
Factors Affecting Customer Retention in the Airline Industry

Abstract Purpose: This study empirically investigated the factors that affect customer retention in the airline industry in North Cyprus. These factors were service quality attributes, perceived safety, customer satisfaction, loyalty reward program, relationship commitment and customer loyalty. The study also investigated four different groups for purposes of travel (business, education, vacation and family visit) in the empirical model. Methodology: A descriptive approach was chosen to conduct this research. A quanhip between customer retention and the related study factors; however, not all of these relations are significant. The results also showed that the different purposes of travel had different influences on the variables regarding the positive and significant relations between them. Some independent variables had a negative effect on the dependent variables. Conclusions: This research was limited to one group and place: the students of Eastern Mediterranean University in North Cyprus. Originality: This study connected the retention, loyalty, satisfaction and service quality factors as attributes. In addition, this research was the first to include other independent factors affecting satisfaction and loyalty in a comparison between four different groups regarding the purpose of travel in the airline industry.