Miracle-dz/UniFAR-FTUs huggingface dataset:
Semantic‐Based Information Retrieval for Content Management and Security

An information retrieval system has to retrieve all and only those documents that are relevant to a user query, even if index terms and query terms are not matched exactly. However, term mismatches between index terms and query terms have been a serious obstacle to the enhancement of retrieval performance. In this article, we discuss automatic term normalization between words and phrases in text corpora and their application to a Korean information retrieval system. We perform three new types of term normalizations: transliterated word normalization, noun phrase normalization, and context‐based term normalization. Transliterated words are normalized into equivalence classes by using contextual similarity to alleviate lexical term mismatches. Then, noun phrases are normalized into phrasal terms by segmenting compound nouns as well as normalizing noun phrases. Moreover, context‐based terms are normalized by using a combination of mutual information and word context to establish word similarities. Next, unsupervised clustering is done by using the K‐means algorithm and cooccurrence clusters are identified to alleviate semantic term mismatches. These term normalizations are used in both the indexing and the retrieval system. The experimental results show that our proposed system can alleviate three types of term mismatches and can also provide the appropriate similarity measurements. As a result, our system can improve the retrieval effectiveness of the information retrieval system.
The algebraic topology of bloch points

Open theoretical problems concerning Bloch points still impede progress in magnetic bubble technology. The author attempts to show why the main approaches to understanding Bloch points are equivalent and have their formal justification in the Hopf extension theorem of algebraic topology. Specifically, E. Feldtkeller's (1965) S/sup 2/ winding number, J.C. Slonzcewski's (1979) gyrovector integral, and the usual topological charge associated with the Heisenberg ferromagnet are seen to be equivalent ways of calculating the degrees of a map into the order parameter space S/sup 2/. This approach is used to clarify the topological constraints which are respected in Bloch point creation and annihilation. The author concludes with some difficult open problems for which the topological approach needs to be supplemented by energetics and numerical simulation. >
Modeling and Simulation of Low Carbon Supply Chain Based on the Product Attributes

The influence of product attributes on low carbon supply chain is studied in this paper. In the background of global emphasis on green and low carbon economy, there are low carbon and quality attributes for the product. In order to meet the requirements of the consumer demand, the enterprise needs to coordinate the relationship between quality and low carbon products at the same time. So the enterprise should adjust of low carbon action to achieve product quality attributes and product attributes to the low carbon balance. Based on the two variable utility theory, through the construction of the supply chain demand structure model, the influence of the product attributes in the supply chain is simulated and analyzed by numerical calculation of low-carbon supply chain process.
"Almost blind" steering vector estimation using second-order moments

The problem of separation and reconstruction of superimposed signals using an array of sensors attracted considerable interest. The estimation of the steering vectors of an uncalibrated array is considered. We identify a cost function whose minimizer is a statistically consistent estimate of the unknown parameters. Next, we present an iterative algorithm for finding a local minimum of that cost function. The proposed algorithm is guaranteed to converge, the performance of the algorithm is compared with the Cramer-Rao bound (CRB).
The FRAX tool in French women: How well does it describe the real incidence of fracture in the OFELY cohort

The FRAX tool estimates an individual's fracture probability over 10 years from clinical risk factors with or without bone mineral density (BMD) measurement. The aim of our study was to compare the predicted fracture probabilities and the observed incidence of fracture in French women during a 10‐year follow‐up. The probabilities of fracture at four major sites (hip, clinical spine, shoulder, or wrist) and at the hip were calculated with the FRAX tool in 867 women aged 40 years and over from the Os des Femmes de Lyon (OFELY) cohort.The incidence of fracture was observed over 10 years. Thus 82 women sustained 95 incident major osteoporotic (OP) fractures including 17 fractures at the hip. In women aged at least 65 years (n = 229), the 10‐year predicted probabilities of fracture with BMD were 13% for major OP fractures and 5% for hip fractures, contrasting with 3.6% and 0.5% in women younger than 65 years (p < .0001). The predicted probabilities of both major OP and hip fractures were significantly higher in women with osteoporosis (n = 77, 18% and 10%) and osteopenia (n= 390, 6% and 2%) compared with women with normal BMD (n = 208, 3% and <1%; p < .0001. The predicted probabilities of fracture were two and five times higher in women who sustained an incident major OP fracture and a hip fracture compared with women who did not (p < .0001). Nevertheless, among women aged at least 65 years with low BMD values (T‐score ≤ –1; n = 199), the 10‐year predicted probability of major OP fracture with BMD was 48% lower than the observed incidence of fractures (p < .01). A 10‐year probability of major OP fracture higher than 12% identified more women with incident fractures than did BMD in the osteoporotic range (p < .05). In French women from the OFELY cohort, the observed incidence of fragility fractures over 10 years increased with age following a pattern similar to the predicted probabilities given by the FRAX tool. However, in women aged at least 65 years with low BMD, the observed incidence of fractures was substantially higher than the predicted probability. © 2010 American Society for Bone and Mineral Research.
Brain inflammation following stroke and cardiac arrest-Restraining neuroinflammation and subsequent psychiatric disorders

General hypothesis Microglia in the injured brain comprise a family of cells with different phenotypes and origin; some which are beneficial for the injured CNS and others that are more of a destructive nature. The different phases of inflammation need to be controlled, from the acute, subacute phase of the injury in the brain. The basic questions we ask are: How can destructive microglia/neuroinflammation be regulated into a protective mode? Can modulation of neuroinflammation mitigate post-stroke depression/anxiety. What instructs microglia to acquire a particular phenotype and is the phenotype of resident microglia different from the phenotype of blood-derived microglia?
Nuclear Import of Insulin-like Growth Factor-binding Protein-3 and -5 Is Mediated by the Importin β Subunit*

Although insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 are known to modulate cell growth by reversibly sequestering extracellular insulin-like growth factors, several reports have suggested that IGFBP-3, and possibly also IGFBP-5, have important insulin-like growth factor-independent effects on cell growth. These effects may be related to the putative nuclear actions of IGFBP-3 and IGFBP-5, which we have recently shown are transported to the nuclei of T47D breast cancer cells. We now describe the mechanism for nuclear import of IGFBP-3 and IGFBP-5. In digitonin-permeabilized cells, where the nuclear envelope remained intact, nuclear translocation of wild-type IGFBP-3 appears to occur by a nuclear localization sequence (NLS)-dependent pathway mediated principally by the importin β nuclear transport factor and requiring both ATP and GTP hydrolysis. Under identical conditions, an NLS mutant form of IGFBP-3, IGFBP-3[228KGRKR → MDGEA], was unable to translocate to the nucleus. In cells where both the plasma membrane and nuclear envelope were permeabilized, wild-type IGFBP-3, but not the mutant form, accumulated in the nucleus, implying that the NLS was also involved in mediating binding to nuclear components. By fusing wild-type and mutant forms of NLS sequences (IGFBP-3 [215–232] and IGFBP-5 [201–218]) to the green fluorescent protein, we identified the critical residues of the NLS necessary and sufficient for nuclear accumulation. Using a Western ligand binding assay, wild-type IGFBP-3 and IGFBP-5, but not an NLS mutant form of IGFBP-3, were shown to be recognized by importin β and the α/β heterodimer but only poorly by importin α. Together these results suggest that the NLSs within the C-terminal domain of IGFBP-3 and IGFBP-5 are required for importin-β-dependent nuclear uptake and probably also accumulation through mediating binding to nuclear components.
Sistemas de Recomendaciones: Una herramienta para mejorar la gestión de la información en las PYMES

espanolLa aparicion de los sitios web, el crecimiento de las redes sociales, la busqueda de formas mas eficiente de recaudar informacion y analizarlas para la toma decisiones en tiempo real y la forma de como las personas se agrupan y planean consumir productos y/o servicios como parte de una actividad conjunta nacen los sistemas de recomendadores(SR) siendo este objeto de nuestro estudio y cuyo objetivo principal es incrementar el nivel de confianza en la gestion de la informacion y la toma de decisiones en las PYMES aplicando SR. La linea de investigacion en recomendadores, que se encuentra actualmente en auge, sufre una serie de deficiencias, radicadas en un incorrecto modelado de los comportamientos sociales de los usuarios, que reducen su eficiencia. El presente estudio es de tipo documental, descriptivo y de campo. En cuanto a las tecnicas se aplico revision documental, cuestionario y la entrevista para as i tener una nocion global del espectro de estudio. En cuanto a los resultados obtenidos, microempresarios que son objeto de este estudio manifestaron la necesidad de disponer de un sitio que mejore la busqueda ordenada de informacion por recomendaciones aplicando un modelo de busqueda especifico mejorado el proceso de la toma de decisiones y los servicios al cliente. EnglishThe appearance of websites, the growth of social networks, the search for forms more efficient to collect information andanalyses them for making decisions in real time and the way people gather and plan to consume products and/or services. As partof a joint activity, the recommender (SR) systems are born this object of our study and whose main objective is to increase the levelof confidence in the management of information and decision making in SMEs applying MR. The line of research on recommender,which is currently booming, suffers a series of deficiencies, rooted in an incorrect modeling of the social behaviors of users, whichreduce their efficiency. The present study is a documentary, descriptive and field type. As for the techniques, a revision was applieddocumentary, questionnaire, and interview therefore as for having a global notion of the spectrum of study. Regarding the resultsobtained, micro-entrepreneurs who are the object of this study showed the need to have a site that improves the orderly search ofinformation by recommendations applying a specific search model improved the process of decision making and customer services
Landscapes, Long Tails and Digital Materialities: Implications for Mobile HCI Research

Mobile HCI is changing. From being about, for example, UI design for small devices, interaction via limited input modalities, and design for small screens, these important aspects of mobile HCI are now heavily interwoven in complex arrangements of computational devices, platforms and services. With a point of departure taken in these processes of current development, this paper sets out to describe and envision a research agenda for mobile HCI carefully crafted out in relation to three specific and recent developments in this field. More specifically, these strands of developments include the formation of new interaction landscapes, the long tail of interaction, and digital materialities. This paper presents the background of each followed by examples illustrating how these three manifest themselves in practice. With a point of departure taken in these three cornerstones a research agenda is presented followed by a discussion on the implications of this agenda for mobile HCI research.
A fuzzy logic-based information security management for software-defined networks

In terms of network security, software-defined networks (SDN) offer researchers unprecedented control over network infrastructure and define a single point of control over the data flows routing of all network infrastructure. OpenFlow protocol is an embodiment of the software-defined networking paradigm. OpenFlow network security applications can implement more complex logic processing flows than their permission or prohibition. Such applications can implement logic to provide complex quarantine procedures, or redirect malicious network flows for their special treatment. Security detection and intrusion prevention algorithms can be implemented as OpenFlow security applications, however, their implementation is often more concise and effective. In this paper we considered the algorithm of the information security management system based on soft computing, and implemented a prototype of the intrusion detection system (IDS) for software-defined network, which consisting of statistic collection and processing module and decision-making module. These modules were implemented in the form of application for the Beacon controller in Java. Evaluation of the system was carried out on one of the main problems of network security - identification of hosts engaged in malicious network scanning. For evaluation of the modules work we used mininet environment, which provides rapid prototyping for OpenFlow network. The proposed algorithm combined with the decision making based on fuzzy rules has shown better results than the security algorithms used separately. In addition the number of code lines decreased by 20-30%, as well as the opportunity to easily integrate the various external modules and libraries, thus greatly simplifies the implementation of the algorithms and decision-making system.
Electrical Features of the Wallace Dam Pumped Hydro Project

The Wallace Dam Pumped Hydro Project was placed in full commercial operation in December 1980. This paper describes the significant features of this combination run-of-river and pumped storage project. Full-voltage, across-the-line starting is used for the 83,000 hp motors, making this the largest known unit using this starting method. The control system, using hard-wired, relay logic is also described.
1.9-ps Jitter, 10.0-dBm-EMI Reduction Spread-Spectrum Clock Generator With Autocalibration VCO Technique for Serial-ATA Application

A spread-spectrum clock generator (SSCG) that is characterized by a low jitter voltage-controlled oscillator (VCO) with a high-frequency limiter and an autocalibration function is developed for a Serial-ATA application. The high-frequency limiter prevents the SSCG from going into an unlocked state. The proposed VCO achieved far less jitter than a conventional one because a proposed structure has fewer operating MOSs that are noise sources. The autocalibration technique calibrates the VCO sensitivity, the maximum frequency of the VCO output signal, and the characteristics of the limit function to prevent the SSCG from degrading an output jitter and an electromagnetic interference (EMI) reduction due to a process variation. The proposed SSCG with the autocalibration function was fabricated in a 0.13-μm CMOS process. The variation in the jitter in 250-cycles at 1.5 GHz with spread-spectrum clocking (SSC) is improved from 2.1-7.8 ps to 1.9-3.3 ps and the EMI reduction is achieved as 10.0 dBm by the proposed autocalibration technique.
Respiratory Syncytial Virus Enhances the Expression of CD11b Molecules and the Generation of Superoxide Anion by Human Eosinophils Primed with Platelet-Activating Factor

Background: Human respiratory syncytial virus (RSV) infection in infancy and early childhood causes acute bronchiolitis and exacerbates bronchial asthma. Eosinophil infiltration may contribute to airway obstruction in RSV infection. Objective: We hypothesized that RSV affects eosinophil function. Methods: Eosinophil activation was evaluated by chemiluminescent detection of superoxide anion (O–2) generation. Expression of CD11b on eosinophils was determined by flow cytometry. Results: Although RSV did not induce O–2 generation by resting eosinophils, RSV enhanced O–2 generation of eosinophils primed with platelet-activating factor (PAF). Enhancement was significantly inhibited by either continuous agitation to prevent eosinophil adhesion to test tube surfaces or by pretreating cells with anti-CD18 antibody, suggesting that the stimulatory effects of RSV on eosinophils depend on cell adhesion via β2-integrins. In fact, RSV enhanced PAF-induced CD11b expression by eosinophils. Conclusion: These findings suggest that RSV enhances eosinophil CD11b expression and O–2 generation induced by PAF. Thus, RSV infection may exacerbate airway inflammation by enhancing mediator release from eosinophils.
Regulation of Amyloid Precursor Protein Cleavage

Abstract : Multiple lines of evidence suggest that increased production and/or deposition of the β‐amyloid peptide, derived from the amyloid precursor protein, contributes to Alzheimer's disease. A growing list of neuro‐transmitters, growth factors, cytokines, and hormones have been shown to regulate amyloid precursor protein processing. Although traditionally thought to be mediated by activation of protein kinase C, recent data have implicated other signaling mechanisms in the regulation of this process. Moreover, novel mechanisms of regulation involving cholesterol‐, apolipoprotein E‐, and stress‐activated pathways have been identified. As the phenotypic changes associated with Alzheimer's disease encompass many of these signaling systems, it is relevant to determine how altered cell signaling may be contributing to increasing brain amyloid burden. We review the myriad ways in which first messengers regulate amyloid precursor protein catabolism as well as the signal transduction cascades that give rise to these effects.
Salmonella: immune responses and vaccines.

Salmonella infections are a serious medical and veterinary problem world-wide and cause concern in the food industry. Vaccination is an effective tool for the prevention of Salmonella infections. Host resistance to Salmonella relies initially on the production of inflammatory cytokines leading to the infiltration of activated inflammatory cells in the tissues. Thereafter T- and B-cell dependent specific immunity develops allowing the clearance of Salmonella microorganisms from the tissues and the establishment of long-lasting acquired immunity to re-infection. The increased resistance that develops after primary infection/ vaccination requires T-cells cytokines such as IFNgamma TNFalpha and IL12 in addition to opsonising antibody. However for reasons that are not fully understood seroconversion and/or the presence of detectable T-cell memory do not always correlate with the development of acquired resistance to infection.Whole-cell killed vaccines and subunit vaccines are used in the prevention of Salmonella infection in animals and in humans with variable results. A number of early live Salmonella vaccines derived empirically by chemical or u.v. mutagenesis proved to be immunogenic and protective and are still in use despite the need for repeated parenteral administration. Recent progress in the knowledge of the genetics of Salmonella virulence and modern recombinant DNA technology offers the possibility to introduce multiple defined attenuating and irreversible mutations into the bacterial genome. This has recently allowed the development of Salmonella strains devoid of significant side effects but still capable of inducing solid immunity after single oral administration. Live attenuated Salmonella vaccines have been used for the expression of heterologous antigens/proteins that can be successfully delivered to the immune system. Furthermore Salmonella can transfer plasmids encoding foreign antigens under the control of eukaryotic promoters (DNA vaccines) to antigen-presenting cells resulting in targeted delivery of DNA vaccines to these cells. Despite the great recent advances in the development of Salmonella vaccines a large proportion of the work has been conducted in laboratory rodents and more research in other animal species is required.
Mesure sans contact de l'activité cardiaque par analyse du flux vidéo issu d'une caméra numérique : extraction de paramètres physiologiques et application à l'estimation du stress

Le sujet des travaux de recherche presente dans cette these de doctorat concerne la conception et le developpement d’une approche basee sur le traitement du signal et des images permettant de mesurer des signaux physiologiques d’une personne situee a distance du capteur. Les differents procedes proposes dans ce travail cherchent a repondre a des besoins particuliers du domaine de l’e-sante, de la telemedecine et de l’informatique affective. Les mesures sans contact de parametres physiologiques sont utilisables dans de nombreux champs d’application, allant des services d’urgence jusqu’aux sciences du sport, ou le rythme cardiaque est surveille pendant un effort physique intense. L’approche developpee est basee sur le calcul des signaux photoplethysmographiques (PPG) obtenus sur des visages humains et enregistres par une webcam. Ces derniers sont ensuite analyses par une transformee en ondelettes continue afin d’en extraire le rythme cardiaque et la frequence respiratoire ainsi que la variabilite cardiaque. Des operations de traitement du signal et des images ont ete developpees pour ameliorer la robustesse du systeme en le rendant moins sensible aux mouvements et aux fluctuations de l’eclairage. La frequence respiratoire est estimee a partir de la variabilite cardiaque par le phenomene d’arythmie sinusale respiratoire, la variation naturelle de la frequence cardiaque entrainee par la respiration. Les phenomenes de vasoconstriction et vasodilatation qui modifient les amplitudes du signal PPG sont aussi detectees par la methode que nous proposons dans ces travaux de these. Les performances du systeme ont ete evaluees a partir d’un ensemble de capteurs standards en contact sur 12 individus en bonne sante qui ont participe aux experiences. Les resultats montrent que les mesures derivees de la webcam et des capteurs en contact sont en etroite concordance. Le second volet de ces travaux de recherche concerne la reconnaissance du stress basee sur les donnees physiologiques quantifiees precedemment. La webcam est ici utilisee pour mesurer et estimer l’etat de tension mentale d’une personne. Les amplitudes du signal PPG et la variabilite de la frequence cardiaque refletent l’etat du systeme nerveux autonome et ont ete utilisees pour calculer une courbe de stress. L’activite electrodermale a concurremment ete mesuree par un capteur en contact pour evaluer la methode que nous proposons. Une application a specifiquement ete developpee en laboratoire pour successivement induire du stress et relaxer les participants. Les resultats indiquent que les mesures calculees a partir des donnees de la webcam sont en etroite correlation avec l’activite electrodermale. La methode presentee dans ces travaux permet de mesurer un ensemble de donnees physiologiques et estimer l’etat de stress d’une personne a l’aide d’une webcam, fournissant ainsi une bonne alternative aux dispositifs conventionnels en contact