Miracle-dz/UniFAR-FTUs huggingface dataset:
The Perceptions of Success of Latino Nursing School Graduates in the Appalachian Region of the United States

This qualitative narrative descriptive study focused on nine successful Latino nursing school graduates. Five participants were interviewed twice and four participants were interviewed once for a total of fourteen interviews. Participants and their families immigrated from Brazil, Costa Rica, Cuba, and Mexico. Participants attended school in North Carolina, South Carolina, and Tennessee. Interviews revealed themes of Familism, Empowerment, and Perseverance. Familism was an overriding theme throughout each of the interviews. Participants described family as being their greatest support. They discussed sacrifices made by their families which assisted them in being successful. In addition, they also shared their willingness to make personal sacrifices in order to honor their family by being successful. Empowerment was also a theme which surfaced. Participants were empowered to attain their goal of attending college and then succeeding in nursing school. The theme of Empowerment was supported by descriptions of parental sacrifice, parental and family support, and support of faculty. The theme of perseverance was demonstrated through continued goal-attainment. Participants struggled through time-management issues such as balancing family, work, and school commitments. They also worked through the guilt of not providing 100% of their time and attention to any one area of their life, especially family. Perseverance was displayed in multiple ways by participants. One of the most compelling was their need to honor their family. Another area which fueled their perseverance was faith. Lastly, participants stated that their need to be self-sufficient added to their perseverance. Self-efficacy surfaced as an attribute they all attained. Familism, perseverance, and empowerment were themes which were consistent with other studies. However, this study is the first study to address the successfulness of Latino nursing school graduates in the Appalachian area of the United States. This study is also unique in that each of the participants attributed their success to family. In addition, seven of the nine families immigrated to the United States for sole purpose of educating their children. This act of sacrifice by families further strengthened the theme of familism.
Evaluation de l'efficacité et du risque des outils du sevrage tabagique par les médecins de Midi-Pyrénées

Introduction : Le tabagisme a toujours une forte prevalence en France avec 36% de fumeurs. Celui-ci tue un fumeur sur deux soit 78000 personnes par an et est la premiere cause de deces premature. C'est pourquoi maitriser les outils du sevrage tabagique est capital. L'usage de la cigarette electronique en tant qu'outil de sevrage tabagique fait debat au sein de la communaute medicale. Objectif : Evaluer l'efficacite et le risque percus par les medecins generalistes, cardiologues et pneumologues des outils du sevrage tabagique (TNS patchs, oraux, cigarette electronique, methodes psycho-comportementales, medecines alternatives, bupropion, varenicline). Materiel et methode : Etude epidemiologique observationnelle descriptive aupres des medecins generalistes, cardiologues, pneumologues de Midi-Pyrenees en utilisant un questionnaire electronique envoye via l'URPS. Resultats : Sur les 2734 medecins contactes 127 medecins ont repondu (taux de reponse 4,64%). L'efficacite percue des outils du sevrage tabagique sur l'abstinence a 6 mois etait dans un ordre decroissant : les methodes psycho-comportementales, les patchs nicotiniques, les medecines alternatives, les gommes nicotiniques. La cigarette electronique etait jugee aussi efficace que les gommes nicotiniques. La varenicline et le bupropion etaient les methodes jugees les moins efficaces. La dangerosite percue des outils du sevrage tabagique etait par ordre croissant : les methodes psycho comportementales, les medecines alternatives, les patchs et les gommes, puis la cigarette electronique. La varenicline et le bupropion etaient les methodes jugees les plus dangereuses. Conclusion : les methodes jugees les plus efficaces sont aussi celles jugees le moins a risque (methodes psycho comportementales, medecines alternatives, patchs nicotiniques). La cigarette electronique est jugee plus efficace et moins a risque que des outils valides du sevrage tabagique (bupropion, varenicline). Toutefois d'autres etudes randomisees comparatives a grande echelle avec une cigarette electronique de derniere generation sont necessaires pour confirmer sa place en tant qu'outil du sevrage tabagique.
Challenges of Iran Health Transformation Plan about Inpatients Payment: Viewpoint of Experts

Background: The health transformation plan (HTP) was put into action in Iran, in 2014, with 8 service packages. This plan was not implemented as a pilot and therefore, various problems and barriers have since emerged. Objectives: Theaimof thisstudywastoidentifytheeconomicchallengesof inpatientpaymentreductiondirectiveinHTPfromthe perspectives of 2 groups of experts in levels of hospital and university held in 2 time periods. Methods: In this qualitative study, data were collected through semi-structured interviews with 20 participants involved in the healthcare reform in hospitals as well as the executive committee of HTP in universities. Results: Data collection resulted in 36 descriptive codes presenting the economic challenges of the payment reduction directive in thems of insurance / tariﬀs and ﬁnancial aﬀairs in the period of 3 months and 1 year since the beginning. Interviewees then suggested their solutions. Conclusions: Challenges trends over times show that some parts of challenges are changing. In addition, challenges interact with each other and could be avoided just by appropriate planning. On the other hand, execution of this directive was extremely costly for the government; it would be better to allocate resources with meticulous planning and designs.
An efficient actor‐critic reinforcement learning for device‐to‐device communication underlaying sectored cellular network

In this paper, a novel reinforcement learning (RL) approach with cell sectoring is proposed to solve the channel and power allocation issue for a device‐to‐device (D2D)‐enabled cellular network when the prior traffic information is not known to the base station (BS). Further, this paper explores an optimal policy for resource and power allocation between users intending to maximize the sum‐rate of the overall system. Since the behavior of wireless channel and traffic request of users in the system is stochastic in nature, the dynamic property of the environment allows us to employ an actor‐critic RL technique to learn the best policy through continuous interaction with the surrounding. The proposed work comprises of four phases: cell splitting, clustering, queuing model, and channel allocation and power allocation simultaneously using an actor‐critic RL. The implementation of cell splitting with novel clustering technique increases the network coverage, reduces co‐channel cell interference, and minimizes the transmission power of nodes, whereas the queuing model solves the issue of waiting time for users in a priority‐based data transmission. With the help of continuous state‐action space, the actor‐critic RL algorithm based on policy gradient improves the overall system sum‐rate as well as the D2D throughput. The actor adopts a parameter‐based stochastic policy for giving continuous action while the critic estimates the policy and criticizes the actor for the action. This reduces the high variance of the policy gradient. Through numerical simulations, the benefit of our resource sharing scheme over other existing traditional scheme is verified.
Comparison of cardiovascular risk factors in maintenance hemodialysis patients based on phase angle of bioimpedance analysis

Mortality and morbidity rate, especially from cardiovascular disease in hemodialysis patients in Indonesia is still quite high. One of indicator to assess the predictive value of mortality is the phase angle (PhA) of bioimpedance analysis (BIA) scan examination. Determining the comparison of BMI and laboratory data as cardiovascular risk factors in hemodialysis patients based on PhA.A cross-sectional analytical study was done on 155 outpatientsin RasyidaRenal Hospital, Medan in 2016. Patients were two groups, namely PhA<4 group and ≥ 4 group. The comparison of BMI and laboratory data based on PhA were by analyzingthe independent T-test. A P-value <0.05 was considered statistically significant. Most of thepatients are male (56.7%), obese (39.4%), with age 40-59 years (56.1%). Based on PhA, 56.7% patients have PhA ≥4. There are differences in the profile of age (p: 0.01), BMI (p: 0.028) and hemoglobin (p: 0.00) between two groups, but not in the profile of albumin (p: 0.071), total cholesterol (p: 0.65), HDL (p: 0.06), LDL (p: 0.07), triglyceride (p: 0.87), calcium (p: 0.59) and phosphorus (p: 0.17). Based onPhA, the cardiovascular risk factors of hemodialysis patients were determined by age, BMI, and hemoglobin.
The challenges of creating a universal influenza vaccine

The lack of population immunity to the periodically emerging pandemic influenza strains makes influenza infection especially dangerous. The fragmented nature of the influenza virus genome contributes to the formation of influenza virus reassortants containing genomic fragments from different strains. This mechanism is the main reason for the natural influenza virus antigenic diversity as well as for the occurrence of influenza pandemics. Vaccination is the best measure to prevent the spread of influenza infection, but the efficacy of existing vaccines is not sufficient, especially for the elderly and small children. Specific immunity, developed after disease or immunization, poorly protects against infection by influenza viruses of another subtype. In this regard, there is an urgent need for a more effective universal influenza vaccine that provides a long-lasting broad cross-protective immunity, and is able to protect against influenza A and B viruses of all known subtypes. The basic approaches to as well as challenges of creating such a vaccine are discussed in this review
Equipping parents and health providers to address the psychological and social challenges of caring for children living with HIV in Africa. An AIDSTAR-One Activity Final Report.

This report provides information to better understand the psychological and social challenges faced in Africa by perinatally-infected children (aged 0-12 years) their parents/caregivers and their health providers. It explores factors that contribute to the ability of children living with HIV to cope and thrive and identifies the tools and approaches being used to help parents/caregivers and health providers provide psychosocial support (PSS) to these children processes.
Homology modeling and ligand interaction of Cytochrome b protein

Cytochrome b is a component of respiratory chain complex III, also known as the bc1 complex or ubiquinol-cytochrome c reductase. These complexes are involved in electron transport and the genera-tion of ATP and thus play a vital role in the cell. The cytochrome bc1 complex is a membrane-bound enzyme that catalyses the transfer of electrons from ubiquinol to cytochrome c, coupling this process to the translocation of protons across the inner mitochondrial membrane. The function of proteins is generally determined by its three-dimensional (3D) structure. Thus, it would be useful to know the 3D structure of the thousands of protein sequences that are emerging from many genome projects. Structural studies on bio-molecules have changed our perception of the biological world in the last twenty years. A number of efforts have been made on structure prediction. One such technique that has found a wide appreciation is Homology modeling which aims at predicting the 3D structure of biomolecules, relying heavily on resources such as pattern/function and sequence. However, the three-dimensional structure of cytochrome b subunit protein (Accession number C4PKA1) from Homo sapiens remains unknown. In the present study, effort was made to generate the three-dimensional (3D) structure of the cytochrome b based on available template (1BGY) structural homologues from Protein Data Bank and the model validated with standard parameters (Procheck). With the predicted model, the ligand was subjected to docking study using FlexX docking tool. Flexible docking was carried out with the HEM - Protoporphyrin X [Heme] as ligand; which was found to bind at His267, Ile268 and Val343 residues on given generated protein. We therefore concluded that the above mentioned residues were the key residue sites for ligand binding. The predicted model showed better results than the template struc-ture with 0% disallowed regions. This study will be used in broad screening of the protein in the respiratory process and can be fur-ther implemented in future drug designing.
Determination of Purchase Intention Factors on the Online Shop Site

E-Commerce is an affiliation of E-bisnis in electronic media era, which is fifth industry revolution era (digital era). It is shown by many companies using internet as the most effective means to advertise and promote products produced competing either nationally or globally. Indonesia is one of potential market in Asia even in the world with the fifth largest population in the world in 2017, which the population are more than 263 million people; while the internet users up to 30 June 2017 in Indonesia are more than 132 million people. Of 200 respondents, which the mean of age was 18-24 years old. The respondents consisted of 110 male and 90 female, thus the average gender in Solo was male. The result of analysis showed that Trust was positively and significantly influence Purchase intention, Website Quality was positively significantly influence the Purchase intention, and Percived Risk was positively and significantly influence the Purchase intention, so that each improvement of Percived Risk score would improve Purchase intention.
Preferences for antiretroviral therapy services: Qualitative evidence from people living with HIV in Ghana

Antiretroviral therapy (ART) is one of the interventions meant to prolong the progression from HIV to AIDS for People Living with HIV (PLHIVs). Although ART was introduced in Ghana in 2003, there is little or no information about the preferences of those on ART services. The main objective of the study therefore was to examine the preferences of PLHIVs concerning ART services. The data were extracted from a nationwide qualitative study conducted by the Ghana AIDS Commission (GAC) which covered 12 cities/towns sampled from the three ecological zones of Ghana. Focus Group Discussions (FGD) and In-Depth Interviews (IDI) were the methods used in the data collection. A total of 145 FGDs and 171 IDIs were conducted in all the study sites among a wide range of target groups. The data were transcribed and analysed using NUD*IST (Non-numerical Data* Indexing Searching and Theorizing) version 6. The results showed that the hospital was the most preferred place for ART medications and most PLHIVs preferred to receive ART drugs from health personnel, trained PLHIVs or ‘foreigners’. PLHIVs preferred to access ART services free of charge and abhorred delays at ART centres. The preferences of PLHIVs regarding ART services must be considered in policies and programmes aimed at increasing enrolment, retention and coverage of ART in the country.
Evaluation of Epithelial-Mesenchymal Transition Genes Involved in Iranian Gastric Cancer Patients via Transcriptome Analysis

Background: Gastric cancer is one of the most frequent cancers among men and women. Patients with gastric cancer are mostly diagnosed in advanced stages because of asymptomatic progression. Due to the heterogeneity and poor prognosis of this cancer, a comprehensive study at the transcriptome level gene expression is needed to ﬁnd the various genes and mechanisms involved in gastric cancer. Diﬀerentially expressed genes (DEG) derived from high-throughput RNA-sequencing could lead to the achievement of new molecular biomarkers. In this study, after transcriptome reanalysis, we focused on the genes involved in epithelial-mesenchymal transition (EMT)viaextracellularmatrix(ECM). WehaveaimedatﬁndingmRNAlevelchangesinnewcandidategenesamongIranianpatients with gastric cancer. Methods: SixgastriccancerandtwonormalsequencingrawsampledatasetswerecollectedfromtheEuropeanNucleotideArchive (ENA). The bioinformatic pipeline was used to reanalyze raw datasets and get DEGs, using the DESeq2 package. After analyzing, THBS2,OSMR,andCHI3L1geneswereselectedforvalidationandveriﬁcationin25conﬁrmedadenocarcinomagastriccancerpatients and non-malignant normal tissues from the Iranian population by real-time polymerase chain reaction (PCR). Results: The bioinformatic analysis of raw datasets revealed many upregulated and downregulated genes in gastric cancer tissues compared with normal samples. Then, real-time PCR veriﬁed the upregulation of THBS2, OSMR, and CHI3L1 genes in a group of Iranian patientswith gastric cancer. Analyzing graphs showeda signiﬁcant increase inthe expression of targetedgenes in patients with gastric cancer (P < 0.0001, P = 0.0016, and P = 0.0002, respectively). Conclusions: The results validated an obvious increase in the expression of THBS2, OSMR, and CHI3L1 genes in gastric cancer of Iranian patients. These genes are involved in EMT and may have a role in cancer invasion if tested further for their diagnostic and prognostic value in larger sample sizes.
Effects of Petroleum Hydrocarbon Contamination on Soil Bacterial Diversity in the Permafrost Region of the Qinghai-Tibetan Plateau

ABSTRACT The Qinghai-Tibet Plateau, with its high elevation and extreme climate, is a transport artery for a crude oil-importation pipeline in China. However, limited information is available regarding the effect of petroleum hydrocarbon (PH) contamination on soil bacterial diversity. Variations in the bacterial structure and composition after PH pollution were investigated by a combination of artificial simulated pollution and high-throughput DNA sequencing. The results demonstrated that the biodiversity of engine oil-contaminated soil samples was higher than that of diesel oil-contaminated soil samples, and 7 genera were identified from indigenous bacteria as potential oil degraders, including Sulfuritalea, Sphingomonas, Alkanindiges, Rhodococcus, Nocardioides, Rhodoplanes, and Actinobacteria_norank. We present a detailed profile of soil bacteria succession under different oil-pollution conditions, which may help in future studies of in-situ bioremediation in this region.
Musculoskeletal diseases of heavy industrial workers

Objective: The purpose of this study was to investigate the musculoskeletal diseases (MSDs) that occur in heavy industrial workers according to the occupational category, prevalence, environment, and number of physical therapy visits. Design: Retrospective cohort study. Methods: For this study, data was collected of workers who were engaged in heavy industry in Korea and who visited the company physicians and received physical therapy in 2016. Data was collected from 855 subjects and was analyzed. With the data collected, analysis of the type and prevalence of MSDs and the number of physical therapy visits that have occurred according to the occupational category and environment was performed. Results: The most common MSDs were lumbar sprains and spasms (31.1%), and shoulder sprain and spasm (19.4%). In addition, the most common type of MSDs according to the occupational category and environment (occupational type) were lumbar sprain and spasms in 11 occupations, including white collar workers, and in milling, inspection, crane operation, and finishing jobs, shoulder muscle sprain and strain were the most common disorders. Also, the prevalence of MSDs according to occupational category and environment (occupational type) was the highest in workers involved with welding, which was 29.7%. Conclusions: Through this study, the type and prevalence of MSDs according to the occupational category and environment of heavy industrial workers have been confirmed. Further studies are necessary to study the future types of the work patterns of industrial workers and to develop a system for preventing and managing MSDs that may occur.
Treated PDR Reveals Age-Appropriate Vision Deterioration But Distorted Retinal Organization

Purpose We determined the progression of visual function, macular structure, and quality of life in patients with regressed proliferative diabetic retinopathy (PDR) after panretinal photocoagulation (PRP). Methods In this prospective study, 22 patients who underwent PRP for PDR and 11 age-matched control participants underwent examinations at baseline and after 5 years. Visual acuity, contrast sensitivity, reading acuity, frequency doubling perimetry, Humphrey field analyzer, and dark adaptation were measured. The Low Luminance Questionnaire and National Eye Institute Vision Function Questionnaire-25 were administered. Macular spectral-domain optical coherence tomography was taken. Results After 5 years, patients who had previously undergone PRP for PDR (18.4 ± 7.9 years previously) showed significant deterioration in contrast sensitivity, reading acuity, frequency doubling perimetry 24-2 pattern standard deviation, and Humphrey field analyzer 10-2 foveal sensitivity, which were equivalent to age-related decreases in control participants. They revealed no further impairment in vision-related activities on questionnaires. In contrast with controls, their maculas showed pathologic disorganization of the retinal layers, especially the nerve fiber layer, which were thicker and constituted a greater proportion of the overall retinal thickness than the norm and associated with impaired vision. Conclusions Patients with treated PDR had age-related decreases in vision, but stable quality of life. Prior injuries from the diabetes and, possibly, laser treatment led to substantial disruption in the retinal structure, which may explain the loss of vision. Translational Relevance Despite PRP treatment, patients with regressed PDR had pathologic progression of the nerve fiber layer; further investigation may identify a new therapeutic target to reverse the visual deficits.
Ferroscopy for detection of metallic foreign body in traumatic pericarditis and pleural effusions in cattle and buffaloes

This study was conducted on 50 bovines including 33 buffaloes and 17 cattle. Animals included in the study were confirmed cases of traumatic pericarditis (n=38) and pleural effusions (n=12). Ferroscopic examination was done in all animals for foreign bodies in the reticulorumen around 5th to 10th intercostal space. Results of ferroscopy were correlated with radiographic and ultrasonographic findings. Among animals suffering from traumatic pericarditis foreign body was detectable cranial to 6th intercostal space in 21 out of 38 animals, however radiography could reveal a penetrating foreign body in 13 animals only. Also in more than 65% cases of traumatic pericarditis foreign body was detectable on the left side. Radiography missed foreign body in all cases suffering from pleural effusions, but it was detectable on ferroscopy in 5 out of 12 animals selected. Therefore, ferroscopy is a useful tool for confirmation of foreign bodies in cases suspected for traumatic pericarditis and pleural effusion in field practices where facilities for radiography and ultrasonography are not available.