Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of demographic factors and factors of job satisfaction in the processes of personnel management: prediction of staff turnover based on logistic regression

Here a combined approach is considered to the prediction of intentions of an employee of a company to quit, on the basis of demographic factors and job satisfaction factors. The developed method includes preliminary assessment of reliability of data from staff survey, an analysis of correlation dependence, construction of a regression model and a nonlinear predictor to assess a probability of staff turnover. This method allows an expert not only to identify the employees who fall into a zone of probable turnover, but also to adjust the processes of human resource on the basis of the most critical factors. At the stages of the method, an employee of a company has a possibility to reduce the number of factors (by grouping, or discarding insignificant factors). Such a choice is made both on the basis of mathematical indicators and taking into account the experience of an expert from a human resource department. To preserve an expert component, authors of the present study refused applying the automated methods of reducing dimensionality, such as a Principal Component Analysis. The developed method is implemented on the basis of a logistic regression analysis, which allowed us to select a group of individual factors and aspects of job satisfaction that affect staff turnover. In addition, it was found that salary level and marital status are significant predictors for the intentions of staff turnover
1 Conditioned medium derived from notochordal cell-rich nucleus pulposus tissue stimulates matrix production by canine nucleus pulposus cells and bone marrow derived stromal cells

Objectives: Conditioned medium derived from notochordal cell-rich nucleus pulposus tissue (NCCM) was previously shown to have a stimulatory effect on bone marrow stromal cells (BMSCs) and nucleus pulposus cells (NPCs) individually, in mixed species in vitro cell models. The objective of the current study was to assess the stimulatory effect of NCCM on NPCs in a homologous canine in vitro model, and to investigate whether combined stimulation with NCCM and addition of BMSCs provides a synergistic stimulatory effect. Page 1 of 25 T is su e E ng in ee ri ng P ar t A C on di tio ne d m ed iu m d er iv ed f ro m n ot oc ho rd al c el lri ch n uc le us p ul po su s tis su e st im ul at es m at ri x pr od uc tio n by c an in e nu cl eu s pu lp os us c el ls a nd b on e m ar ro w d er iv ed s tr om al c el ls ( do i: 10 .1 08 9/ te n. T E A .2 01 4. 03 09 ) T hi s ar tic le h as b ee n pe er -r ev ie w ed a nd a cc ep te d fo r pu bl ic at io n, b ut h as y et to u nd er go c op ye di tin g an d pr oo f co rr ec tio n. T he f in al p ub lis he d ve rs io n m ay d if fe r fr om th is p ro of . 2 Methods: BMSCs and NPCs were harvested from chondrodystrophic dogs with confirmed early intervertebral disc (IVD) degeneration. NCCM was produced from NP tissue of nonchondrodystrophic dogs with healthy IVDs. BMSCs or NPCs alone (3x10 cells/ml) and NPCs+BMSCs (6x10 cells/ml; mixed 1:1) were cultured for 4 weeks in 1.2% alginate beads under base medium (BM), NCCM, or with addition of 10 ng/ml TGF-β1 as a positive control. Beads were assessed for GAG and DNA contents by biochemical assays, GAG deposition by Alcian Blue staining, and gene expression (aggrecan, versican, collagen 1 and 2, SOX9, ADAMTS5 and MMP13) with RT-qPCR. Results: NCCM increased NPC proliferation, proteoglycan production, and expression of genes associated with a healthy NP-like phenotype. BMSCs also showed increased proteoglycan production under NCCM, but these effects were not observed at the gene level. Combined stimulation of NPCs with NCCM and co-culturing with BMSCs did not result in increased proteoglycan content compared to stimulation with NCCM alone. Discussion: NCCM stimulates matrix production by both NPCs and BMSCs, and directs NPCs towards a healthier phenotype. NCCM is therefore promising for intervertebral disc regeneration, and identification of the bioactive components will be helpful to further develop this approach. In the current study, no synergistic effect of adding BMSCs was observed.
Comparison of embryo development in sibling oocytes cultured in two different sequential media

Objective: To compare the efficiency of two different sequential media for the cultivation of sibling embryos until the blastocyst stage. Design: A prospective analysis was conducted on 113 ART cycles with the indication of severe male factor infertility in Istanbul Memorial Hospital ART and Genetics Unit. Setting: After insemination, oocytes were randomly divided into two groups and cultured with either ISM1/ISM2 or G1.2/G2.2 sequential media until embryo transfer. Embryo development parameters were recorded for every embryo on consecutive days of preimplantation embryo development, growing in each set of culture media. Results: 16.7±6.4 MII oocytes were retrieved. Out of 1434 MII oocytes injected, 1044 were fertilized (72.8%). There was no statistically significant difference in the rate of fertilization (p>0.05). Also, there was no difference in embryo development on the second day of cultivation. On the 3rd day of cultivation, the mean number of blastomeres was significantly higher in embryos cultivated within ISM1 (p<0.01). There was no statistically significant difference among the two groups in terms of blastulation rate. Discussion: Both G1.2-G2.2 and ISM1-ISM2 sequential cultures are equally effective for in-vitro cultivation of embryos until the blastocyst stage. Our results show that both commercial media can be used as valuable and efficient alternatives to each other for sustaining blastocyst development in extended embryo culture programs. ISM1 may be preferred when blastomere biopsy for preimplantation genetic diagnosis is planned as more embryos with 7-8 blastomeres can be available with the use of ISM1.
Neuromuscular biomechanical modeling to understand knee ligament loading.

PURPOSE This article examines our use of EMG-driven neuromuscular biomechanical models to study how muscles stabilize the knee. EMG can be used to establish which activation patterns are used by people for knee stabilization. However, it does not reveal the effectiveness of these patterns. The EMG-driven models provide quantitative comparisons of the effectiveness of the different knee-stabilizing activation patterns. METHODS Subjects performed static tasks and common sporting maneuvers that challenged knee joint stability. EMG, joint posture and motion, and external forces and moments were measured during these tasks. These data were used to calibrate the EMG-driven neuromuscular biomechanical model. We then used the model to predict the role of muscles in supporting varus and valgus moments at the knee. RESULTS We found specific muscle activation patterns to support varus and valgus moments. The most potent activation pattern to stabilize the knee is when the hamstrings or quadriceps are required to generate flexion or extension moments, respectively. The next most effective knee-stabilizing pattern is cocontraction of the hamstring and quadriceps. The small biarticular muscles at the knee provided the least support of varus and valgus moments. In the sporting tasks, sidestepping was found to place the anterior cruciate ligament at high risk of injury. We found that the muscles are the main defense against knee ligament injuries in these tasks. CONCLUSION Traditional biomechanical and neurophysiological methods have shown that there are specific activation patterns used to stabilize the knee. By also using the EMG-driven neuromuscular biomechanical model, we have shown how effective muscles are in stabilizing the knee. This modeling method provides a new tool to understand knee joint stabilization.
Does Hypoadiponectinemia Explain the Increased Risk of Diabetes and Cardiovascular Disease in South Asians? A table elsewhere in this issue shows conventional and Système International (SI) units and conversion factors for many substances.

A substantial body of evidence has documented the high prevalence of type 2 diabetes and cardiovascular disease (CVD) among people of South-Asian descent, defined on the basis of ancestral origin from the Indian subcontinent comprised of India, Pakistan, Bangladesh, and Sri Lanka (1–7). These observations relate to both native South Asians in urban settings and those living overseas in different countries (including the U.K., Canada, the U.S., South Africa, Singapore, Fiji, and Trinidad), leading to the suggestion that members of this ethnic group may share an underlying predisposition to metabolic and vascular disease (3,4,6–10). It has been postulated that a gene-environment interaction between underlying genetic susceptibility and urbanization-induced lifestyle changes (such as increased caloric intake and decreased energy expenditure) may promote the clinical expression of a high-risk phenotype (7). Clinically, this phenomenon translates to a 1.5- to 10-fold–higher incidence of coronary artery disease (CAD) in immigrant South Asians compared with the general populations of the host countries (2–4,10,11). Furthermore, South Asians exhibit clinical features suggestive of a distinctly aggressive cardiovascular pathophysiology compared with other ethnic groups. These features include significantly higher cardiovascular mortality (4,12) and earlier onset of CAD in young adults (7,13). Thus, identification of the determinants of vascular disease in South Asians may be relevant to both 1 ) our understanding of the pathophysiology of CVD and 2 ) preventive health care for the approximately one-fifth of the world’s population that comes from the Indian subcontinent. A similarly worrisome problem is the rising prevalence of type 2 diabetes in South Asians. India currently has the highest number of cases of diabetes in the world (14). In addition, it has been projected that between 2000 and 2030, the number of patients with diabetes …
Streptococcus Adherence and Colonization

SUMMARY Streptococci readily colonize mucosal tissues in the nasopharynx; the respiratory, gastrointestinal, and genitourinary tracts; and the skin. Each ecological niche presents a series of challenges to successful colonization with which streptococci have to contend. Some species exist in equilibrium with their host, neither stimulating nor submitting to immune defenses mounted against them. Most are either opportunistic or true pathogens responsible for diseases such as pharyngitis, tooth decay, necrotizing fasciitis, infective endocarditis, and meningitis. Part of the success of streptococci as colonizers is attributable to the spectrum of proteins expressed on their surfaces. Adhesins enable interactions with salivary, serum, and extracellular matrix components; host cells; and other microbes. This is the essential first step to colonization, the development of complex communities, and possible invasion of host tissues. The majority of streptococcal adhesins are anchored to the cell wall via a C-terminal LPxTz motif. Other proteins may be surface anchored through N-terminal lipid modifications, while the mechanism of cell wall associations for others remains unclear. Collectively, these surface-bound proteins provide Streptococcus species with a “coat of many colors,” enabling multiple intimate contacts and interplays between the bacterial cell and the host. In vitro and in vivo studies have demonstrated direct roles for many streptococcal adhesins as colonization or virulence factors, making them attractive targets for therapeutic and preventive strategies against streptococcal infections. There is, therefore, much focus on applying increasingly advanced molecular techniques to determine the precise structures and functions of these proteins, and their regulatory pathways, so that more targeted approaches can be developed.
Voice onset time in consonant cluster errors: can phonetic accommodation differentiate cognitive from motor errors?

PURPOSE Phonetic accommodation in speech errors has traditionally been used to identify the processing level at which an error has occurred. Recent studies have challenged the view that noncanonical productions may solely be due to phonetic, not phonological, processing irregularities, as previously assumed. The authors of the present study investigated the relationship between phonological and phonetic planning processes on the basis of voice onset time (VOT) behavior in consonant cluster errors. METHOD Acoustic data from 22 German speakers were recorded while eliciting errors on sibilant-stop clusters. Analyses consider VOT duration as well as intensity and spectral properties of the sibilant. RESULTS Of all incorrect responses, 28% failed to show accommodation. Sibilant intensity and spectral properties differed from correct responses irrespective of whether VOT was accommodated. CONCLUSIONS The data overall do not allow using (a lack of) accommodation as a diagnostic as to the processing level at which an error has occurred. The data support speech production models that allow for an integrated view of phonological and phonetic processing.
Mycophenolate mofetil and sirolimus as calcineurin inhibitor-free immunosuppression for late cardiac-transplant recipients with chronic renal failure

Background. Calcineurin-inhibitor (CNI)-related renal failure is a common problem after cardiac transplantation (HTx). The aim of this study was to introduce a CNI-free immunosuppressive regimen to HTx recipients with late posttransplant renal impairment and to evaluate the impact of conversion to this new immunosuppression (mycophenolate mofetil [MMF] and sirolimus [Sir]) treatment on renal function. Methods and Results. Thirty-one HTx patients (25 men, 6 women; 0.2–14.2 years after transplantation) with CNI-based immunosuppression and a serum creatinine greater than 1.9 mg/dL were included in the study. Creatinine and cystatin levels were monitored to detect renal function. Mean patient age was 50±14 (range 19–74) years. Conversion was started with 6 mg Sir, continued with 2 mg, and the dose was adjusted to achieve target trough levels between 8 and 14 ng/mL. MMF was continued with trough level adjusted (1.5–4 &mgr;g/mL). Subsequently, the CNIs were tapered down and stopped. Clinical follow-up (first and every 3 months after conversion) included endomyocardial biopsies, echocardiography, and laboratory studies. Survival was 90% after a mean follow-up of 13±5 months. No acute rejection episode was detected during the study period. Renal function improved significantly after conversion: creatinine preconversion vs. postconversion: 3.14±0.76 mg/dL vs. 2.14±0.83 mg/dL, P =0.001. Cystatin preconversion vs. postconversion: 2.95±1.06 mg/L vs. 2.02±1.1 mg/L, P =0.01. In three patients, hemodialysis therapy was stopped completely after conversion. Graft function remained stable. Fractional shortening preconversion vs. postconversion: 36.9±6% vs. 36.4±6%. There were no serious adverse events. One patient had to be excluded because of noncompliance. Conclusions. Conversion from CNI-based immunosuppression to MMF and Sir in HTx patients with chronic renal failure was safe, preserved graft function, and improved renal function.
Static and dynamical properties of doped Hubbard clusters.

We study the {ital t}-{ital J} and the Hubbard models at zero temperature using exact-diagonalization techniques on {radical}10 {times} {radical}10 and 4{times}4 sites clusters. Quantum Monte Carlo simulation results on larger lattices are also presented. All electronic fillings have been analyzed for the three models. We have measured equal-time correlation functions corresponding to various types of order (ranging from standard'' staggered spin order to more exotic'' possibilities like chiral order), as well as various dynamical properties of these models. Upper bounds for the {ital critical} {ital hole} {ital doping} ({ital x}{sub {ital c}}), where long-range antiferromagnetic order disappears, are presented. It was found that {ital x}{sub {ital c}} is very small in agreement with experiments for the high-{ital T}{sub {ital c}} superconductors. For example, in the {ital t}-{ital J} model, {ital x}{sub {ital c}}{lt}0.08 at {ital J}/{ital t}=0.4. However, short-distance spin correlations are important up to much higher dopings producing a sharp well-defined spin-wave-like peak in {ital S}({bold q}=({pi},{pi}),{omega}). Regarding the possibility of {ital phase} {ital separation} in the Hubbard model, we have studied the behavior of the density of particles, {l angle}{ital n}{r angle}, as a function of the chemical potential, using the Lanczos method on a 4{times}4 Hubbardmore » cluster, finding no indications of phase separation for any value of {ital U}/{ital t}. Then, we conclude that the {ital t}-{ital J} model at small {ital J}/{ital t} should {ital not} phase separate. « less
Readmissions and the quality of care in patients hospitalized with heart failure.

OBJECTIVES Clinical practice guidelines based on the results of randomized clinical trials recommend that patients with heart failure due to left ventricular systolic dysfunction (LVSD) be treated with angiotensin-converting enzyme inhibitors (ACEI) at doses shown to reduce mortality and readmission. This study examined the relationship between ACEI use at discharge and readmission among patients with heart failure due to LVSD. METHODS AND RESULTS Data were abstracted from the medical records of 2943 randomly selected patients hospitalized for heart failure in 50 hospitals. The outcome of interest was the number of readmissions occurring up to 21 months after discharge. Six-hundred and eleven patients were eligible for analysis. Compared with patients discharged at a recommended ACEI dose, patients not prescribed an ACEI at discharge had an adjusted rate ratio of readmission (RR) of 1.74 [95% confidence interval (CI) 1.22-2.48], while patients prescribed an ACEI at less than a recommended dose had an RR of 1.24 (95% CI 0.91-1.69) (P = 0.005 for the trend). CONCLUSION Our results show that ACEI use at discharge in patients with LVSD is associated with decreased rate of readmission. These findings suggest that compliance with the ACEI prescribing recommendations listed in clinical practice guidelines for patients with heart failure due to LVSD confers benefit.
A Predictable Information Security Based Context Aware Trust Model for Organization Management: A Statistical Analysis

The objective of the work is to propose a Predictable Context Aware Trust (PCAT) model for achieving organisation information security in the presence of suspicious entities and authorities. The properties of the PCAT model are studied including the suspicion stack pertaining to the members in different contexts. A reputation score is rewarded based on the contexts in which the information exchange is done. The proposed information trust model encompasses the trust level of the members, degree of suspicion in the information, the levels of privacy, reputation values of the trustees and their trust relationships to predict organization security. An airway passenger guidance system is taken up for statistical analysis. A conceptual and hierarchical trust pyramid is considered at different context levels and the formal implications are derived using context sensitive standard deontic logic. The formal specifications of a passport checking sub system are given in Temporal Logic of Actions (TLA+) which uses certificate authorities and trustees to evaluate passengers by assigning suspicious values.
Corporate Social Responsibility in Municipal Councils of Sri Lanka (With Special Reference to Solid Waste Functions)

There has been a growing knowledge about the corporate social responsibility (CSR) in the modern communities. The CSR includes the feeling or ethics of the good relationship between organizational activities and civil society. There are two kinds of stakeholders in CSR such as internal and external. Three major administration structures can be seen in Sri Lanka; the Central government, Provincial councils and Municipal council (MC). Structure of the MC is the third and lowest level of administration in Sri Lanka. There are 23 MCs in Sri Lanka in 2011. Municipal solid waste is creating a lot of issues in urban areas. The objectives of the study on CSR in MCs of Sri Lanka; to identify stakeholder satisfaction, to recognise priority factors of CSR and to recognise similar groups of the CSR. Sample size is 200. Percentage analysis, multiple regression analysis and factor analysis were used as statistical tools. Aspect of external stakeholders, CSR has failed in MCs in Sri Lanka. Therefore the study recommended that, CSR program can be prepared as a system and mechanism between external stakeholders (employees) and internal stakeholders for getting the maximum benefit for both parties. Due to the cleaning of environment is an important factor for each person for the purpose of reducing or eliminating diseases from society.
Chronic total occlusion is associated with a higher incidence of malapposition and uncovered stent struts: OCT findings at 6 months following DES implantation

To compare stent coverage and malapposition in patients with chronic total occlusion (CTO) lesions and non‐CTO lesions (including lipid‐rich plaque [LRP] and non‐lipid‐rich plaque [non‐LRP]) after drug‐eluting stent (DES) implantation by optical coherence tomography (OCT).
Suzaku observations of 'bare' active galactic nuclei

We present an X-ray spectral analysis of a large sample of 25 ‘bare’ active galactic nuclei (AGN), sources with little or no complicating intrinsic absorption, observed with Suzaku. Our work focuses on studying the potential contribution from relativistic disc reflection and examining the implications of this interpretation for the intrinsic spectral complexities frequently displayed by AGN in the X-ray bandpass. During the analysis, we take the unique approach of attempting to simultaneously undertake a systematic analysis of the whole sample, as well as a detailed treatment of each individual source, and find that disc reflection has the required flexibility to successfully reproduce the broad-band spectrum observed for all of the sources considered. Where possible, we use the reflected emission to place constraints on the black hole spin for this sample of sources. Our analysis suggests a general preference for rapidly rotating black holes, which if taken at face value is most consistent with the scenario in which supermassive black hole growth is dominated by prolonged, ordered accretion. However, there may be observational biases towards AGN with high spin in the compiled sample, limiting our ability to draw strong conclusions for the general population at this stage. Finally, contrary to popular belief, our analysis also implies that the dichotomy between radio-loud/radio-quiet AGN is not solely related to black hole spin.
PENGARUH KOMPENSASI EKSEKUTIF, LEVERAGE, STRUKTUR KEPEMILIKAN DAN KOMISARIS INDEPENDEN TERADAP PENGHINDARAN PAJAK (TAX AVOIDANCE)

This study aims to determine the effect of executive compensation, structure ownership, leverage and independent commissioner to tax avoidance in companies listed on the Indonesian Stock Exchange in 2011-2014. Proxy of structure ownership variables consist of institutional ownership ,public ownership.In this research, sample selection using purposive sampling method . Purposive sampling method is a method of sample selection based on the criteria desired by the researcher. From this research, obtained a sample of 23 companies out of 146 companies listed on the Stock Exchange from 2011-2014. Analysis of the data in this study is done by using a test that analysis , multiple linear regression analysis , the classical assumption test , and hypothesis testing . The test results in this study show variable composition of the leverage, institutional ownership and independent commissioner , did has not significant effect on the activity of tax avoidance . While the variable executive compensation and public ownership has significantly effect on of tax avoidance Keywords : tax avoidance, executive compensation, leverage, structure ownership, independent commisioner