Miracle-dz/UniFAR-FTUs huggingface dataset:
Me and My Web Shadow: How to Manage Your Reputation Online

Social networking on the web has vastly increased the amount of personal information available for nearly anyone to see. This information, once out of your control, can link details of your personal and work life to neighbors, co-workers, potential business associates, and even dating prospects! While most books give advice about the benefits of social networking and how to use Google, MySpace, and Facebook, this is the first book to address how to understand and manage what people seewhen they look for you online and how to protect your online shadow. The author is a world-renowned digital expert who has worked with clients such as Coca-Cola and Toyota in shaping their online reputation and can help social networkers, business owners, corporate PR specialists, academics, and journalists develop a personal action plan to: Set up and manage your online reputation in social networks and the wider web. Protect yourself from identity theft, account hijacking, and cyber-bullying. Create career and business opportunities by taking part in select social networks and online communities while understanding how associating with these groups can affect your work and personal life
A Milestone in the Milestones Movement: the JGME Milestones Supplement.

The definition of the current competencies as well as their optimal assessment has remained controversial. ,14,15 The purpose of competency assessment will need to be clarified, beyond formative vs. summative. Multiple agendas derived from different stakeholders may need to give way to the few that directly impact the goal of producing high caliber, independent practitioners.16 Streamlining the various purposes for assessment will be an important issue for the embryonic milestones as well. The reality for most training programs is that the supply of time and money is decreasing. No matter how laudable the goals of valid, reliable, and national educational outcomes, their implementation must be feasible within this reality. Therefore cost-effectiveness will need to be considered in future assessment studies. We must ensure the competent performance of graduate physicians, in the right balance of specialties, at a reduced cost to the nation; the milestones project may well be measured by how well it contributes to these aims. Will milestones advance the field of assessment and mark a turning point in GME? We urge readers to continue to the national conversation that seeks answers to these questions.
The Value of China Steam Coal Supply Chain Information Sharing and Impact of Lead-Time and Seasonal Factor

The steam coal supply chain has the problem that the member’s inventory level cannot change with the market demand. The main reason is that market demand information has not been shared in the supply chain members. This paper considers the steam coal supply chain which consists of one coal manufacturer and one fire power plant, with the assumption that the steam coal demand follows a seasonal autoregressive moving average process, including marketing actions that cannot be deduced form the other parameters of the demand process. We compare the optimal inventory level of the steam coal manufacturer and the power plant in two scenarios and analyses the reasons that influence the value of the information sharing in the steam coal supply chain. It demonstrates that the seasonal effect and lead-time have an important impact on optimal inventory policy. This result provides managers of steam coal manufacturers and power plant with insights to establish strategic partnership to promote the performance of the whole supply chain.
Market-oriented sustainability: moderating impact of stakeholder

Purpose – The theoretical framework for market-oriented sustainability developed by Crittenden, Crittenden, Ferrell, Ferrell, and Pinney, in which the relationship between organizational culture and performance management is theorized as moderated by stakeholder involvement, is empirically assessed. The paper aims to discuss these issues. Design/methodology/approach – Crittenden et al. model is operationalized using market orientation to represent organizational culture and climate, logistics performance to represent performance management, and green purchasing to represent the moderator stakeholder involvement in sustainability. The model is assessed using data collected from a sample of 257 manufacturing managers working for US manufacturing plants. A partial least squares structural equation modeling approach is used to statistically assess for measurement scale validity and reliability and the moderated model. Findings – The results support the conceptual framework for market-oriented sustainability theorized by Crittenden et al. Organization culture in the form of market orientation interacts with stakeholder involvement in sustainability in the form of green purchasing to enhance performance monitoring in the form of logistics performance. Research limitations/implications – This study is one of the first to empirically assess the market-oriented sustainability model. Only one set of potential constructs (market orientation, green purchasing, and logistics performance) is used to test the overall model thus limiting the generalization of the results. Practical implications – The results indicate that manufacturing managers should work to establish and improve market orientation as a direct way of making their plants and organizations environmentally sustainable and that manufacturing managers interact with supply chain partners, specifically suppliers, to satisfy customer demands for eco-friendly products and services. Originality/value – This is one of the first studies to empirically assess the general form of the market-oriented sustainability model.
Thermal test- and field cycling induced degradation and its FE-based prediction for different SAC solders

A study of the performance of different Sn based solder alloys applied for large to small sized solder interconnects was undertaken. From the theoretical and experimental investigations on creep, fatigue and brittle fracture behaviors the paper focuses on the low cycle fatigue performance in test and field thermal environments. Special focus was put on a newly developed highly creep resistant solder alloy "Innolot" (SnAg3.8Cu0.7Bi3.0Sbl.4Ni0.2). In addition to results of previous studies on lead free materials, particularly their long- term durability and their microstructure-properties dependence was addressed. Phenomenological models based on finite element analyses including solder creep behaviors were applied to study the component and cyclic regime dependent creep straining and creep dissipation in several joints to assess solder failure. For this purpose, creep properties of several solders were measured for ball-type joint sized specimens.
High‐throughput analysis of peptide‐binding modules

Modular protein interaction domains (PIDs) that recognize linear peptide motifs are found in hundreds of proteins within the human genome. Some PIDs such as SH2, 14–3‐3, Chromo, and Bromo domains serve to recognize posttranslational modification (PTM) of amino acids (such as phosphorylation, acetylation, methylation, etc.) and translate these into discrete cellular responses. Other modules such as SH3 and PSD‐95/Discs‐large/ZO‐1 (PDZ) domains recognize linear peptide epitopes and serve to organize protein complexes based on localization and regions of elevated concentration. In both cases, the ability to nucleate‐specific signaling complexes is in large part dependent on the selectivity of a given protein module for its cognate peptide ligand. High‐throughput (HTP) analysis of peptide‐binding domains by peptide or protein arrays, phage display, mass spectrometry, or other HTP techniques provides new insight into the potential protein–protein interactions prescribed by individual or even whole families of modules. Systems level analyses have also promoted a deeper understanding of the underlying principles that govern selective protein–protein interactions and how selectivity evolves. Lastly, there is a growing appreciation for the limitations and potential pitfalls associated with HTP analysis of protein–peptide interactomes. This review will examine some of the common approaches utilized for large‐scale studies of PIDs and suggest a set of standards for the analysis and validation of datasets from large‐scale studies of peptide‐binding modules. We will also highlight how data from large‐scale studies of modular interaction domain families can provide insight into systems level properties such as the linguistics of selective interactions.
Inherited susceptibility to common cancers.

This review deals with germ-line genes that increase susceptibility to five major types of cancer: breast, lung, pancreatic, prostate, and colorectal cancer. Often familial, often appearing at a young age, and often with atypical features, these cancers are caused by mutations in a germ-line gene and frequently with a second mutation in a gene in a somatic cell. The review ends with a discussion of clinical implications, especially for genetic counseling.
Semaphorin 3A‐mediated axon guidance regulates convergence and targeting of P2 odorant receptor axons

Semaphorins are known to play an important role in axon guidance of vertebrate olfactory sensory neurons to their targets in specific glomeruli of the olfactory bulb (OB). However, it is not clear how semaphorin‐mediated guidance contributes to a systematic hierarchy of cues that govern the organization of this system. Because of the putative role that odorant receptor molecules such as P2 could play in establishing appropriate glomerular destinations for growing olfactory axons, we have also determined the spatial organization of P2 glomeruli in semaphorin 3A (Sema3A) mutant mice. First, in the postnatal OB of control and Sema3A−/− mice, we analysed the trajectories of olfactory axons that express the Sema3A receptor, neuropilin‐1 (npn‐1) and the positions of npn‐1+ glomeruli. Sema3A at the ventral OB midline guides npn‐1+ axons to targets in the lateral and medial OB. Absence of Sema3A permits many npn‐1 axons to terminate aberrantly in the rostral and ventral OB. Second, in Sema3A−/− mice, many P2 axons are abnormally distributed throughout the ventral OB nerve layer and converge in atypical locations compared with littermate controls where P2 axons converge on stereotypically located lateral and medial glomeruli. In addition to their radically altered spatial distribution, P2 glomeruli in Sema3A−/− mice are significantly smaller and more numerous than in heterozygote littermates. These data show that Sema3A is an important repulsive olfactory guidance cue that establishes restricted npn‐1+ subcompartments in the olfactory bulb. Furthermore, Sema3A plays a key role in the convergence of axons expressing the odorant receptor P2 onto their appropriate targets.
Multi-agent simulator of incentive influence on PV adoption

Renewable energy technologies have benefited to varying extent from the support of incentive programmes introduced in the industrialised countries over the last 20 years. Understanding the impact of incentive schemas on the adoption of renewable energy sources is a crucial aspect for policy makers. We study in this paper the impact of national incentives on photovoltaic plant diffusion in Italy by devising an agent-based simulator which is currently being tuned on real data and will help policy makers to forecast future adoptions.
Cattle raising in the United States

Per capita consumption of beef rose from 85 pounds in 1960 to 114 pounds in 1970, and is projected to reach about 128 pounds by 1980. Since 1950, cattle feeding has expanded until most calves are now grain fed before slaughter. Additional beef will have to come mainly from increased numbers of cattle. Beef cows grew from 16.7 million in 1950 to 37.3 million in 1970 and are expected to reach 46.3 million by 1980. Milk cows decreased from 23.9 million to 13.9 million over the same period, and are expected to number 12.1 million by 1980. The Southeast has gained 6.4 million beef cows since 1950 and is expected to add another 2.7 million by 1980. This region offers the greatest potential for future increase of beef cows in the United States. The humid climate and long growing season contribute to good forage production, thus sustaining and encouraging cattle grazing. The Corn Belt and Northern Plains also have substantial growth potential. Changes within the beef industry, improved forage production and utilization, and an expectation of favorable prices are major factors encouraging expansion in cattle raising. Beef and dairy cattle estimated for 1980 will produce about 127 pounds of beef per capita with a projected population of 230 million. Changes in cattle productivity are anticipated, as are changes in import-export balances.
Double Immunolabeling by the RBM and the PLAP Markers for Identifying Intratubular (in Situ) Germ Cell Neoplasia of the Testis

Identification of intratubular germ cell neoplasia (carcinoma in situ, CIS) of the testis is a diagnostic challenge, and markers are sorely needed to assist in accurately identifying the lesion. RNA-binding motif (RBM) protein, encoded by the Y chromosome, is expressed exclusively and consistently in differentiated male germ cells, while it is absent in neoplastic germ cells. Another immunohistochemical marker, placental alkaline phosphatase (PLAP), is commonly used for the detection of undifferentiated germ cells. The current study demonstrates that simultaneous use of the immunohistochemical markers, RBM and PLAP, by double immunolabeling enhances the accuracy of diagnosing CIS, a preinvasive testicular neoplasm.
Specific Binding of Tetratricopeptide Repeat Proteins to the C-terminal 12-kDa Domain of hsp90*

The molecular chaperone hsp90 in the eukaryotic cytosol interacts with a variety of protein cofactors. Several of these cofactors have protein domains containing tetratricopeptide repeat (TPR) motifs, which mediate binding to hsp90. Using a yeast two-hybrid screen, the 12-kDa C-terminal domain of human hsp90α (C90) was found to mediate the interaction of hsp90 with TPR-containing sequences from the hsp90 cofactors FKBP51/54 and FKBP52. In addition, the mitochondrial outer membrane protein hTOM34p was identified as a TPR-containing putative partner protein of hsp90. In experiments with purified proteins, the TPR-containing cofactor p60 (Hop) was shown to form stable complexes with hsp90. A deletion mutant of hsp90 lacking the C90 domain was unable to bind p60, whereas deletion of the ∼25-kDa N-terminal domain of hsp90 did not affect complex formation. Both p60 and FKBP52 bound specifically to the C90 domain fused to glutathione S-transferase and competed with each other for binding. In reticulocyte lysate, the C90 fusion protein recognized the TPR proteins p60, FKBP52, and Cyp40. Thus, our results identify the C90 domain as the specific binding site for a set of hsp90 cofactors having TPR domains.
Welfare Recipients' Road to Economic Self-Sufficiency: Job Quality & Job Transition Patterns Post-PRWORA

Although the long-run success or failure of PRWORA will rest, in large part, on welfare recipients’ abilities to eventually obtain stable full-time employment earning a living wage, we know very little about the extent of employment continuity once recipients start jobs or about the quality of jobs former/current welfare recipients have obtained. In this paper, we use new survey data from Michigan of both employers and longitudinal data of former/current recipients to examine the relationships of schooling, work experience, the skill content of recent work experience, and different types of employment patterns (job stability, job mobility, job instability) with women’s job quality outcomes, to attempt to shed light on the pathways through which successful transitions into “good” jobs are made. We broaden the analysis of the quality of employment outcomes beyond employment rates and wages measured at a point in time to include non-wage attributes of compensation (such as desirability of work hours and employer-provided health insurance benefits), as well as aspects of jobs that affect future earnings potential (such as training opportunities to learn new skills that affect promotion prospects). This study provides new evidence on the extent to which job instability and a lack of job skills, occupation-specific experience, and training that employers require in “good” jobs impede TANF recipients’ abilities to obtain good jobs or successfully make the transition into them from bad ones.
Conventional, Naive CD4+ T Cells Provide an Initial Source of IL-4 During Th2 Differentiation

IL-4 is known to promote the differentiation of CD4+ T cells into IL-4-secreting Th2 cells. However, the cellular source of the early burst of IL-4 that drives Th2 responses in vivo has not been conclusively identified. Mice deficient for the IL-4 receptor α-chain (IL-4Rα−/−) retain the capacity to secrete IL-4 and can be used to identify those cell types that produce IL-4 without a requirement for prior IL-4-mediated stimulation. To address whether naive, conventional CD4+ T cells may act as initial producers of IL-4 in Ag-specific responses, we crossed the BALB/c IL-4Rα−/−mice to DO11.10/scid TCR transgenic mice. Lymph node cells from wild-type and IL-4Rα−/− DO11.10/scid mice secreted ∼50 pg of IL-4 per106 cells within 48 h after peptide stimulation. This small amount of IL-4 was sufficient to cause the differentiation of wild-type CD4+ T cells into Th2 cells, particularly if IFN-γ and IL-12 were neutralized during the priming cultures. CD4+ cells from the IL-4Rα−/− mice gave rise to a minor proportion (∼2%) of IL-4-producing cells upon stimulation in the presence of anti-IFN-γ and anti-IL-12. These data show that conventional, naive CD4+ T cells may be considered as initial sources of IL-4 and, in the absence of IFN-γ and IL-12, this IL-4 can induce Th2 polarization.
Conservadorismo contábil e a adoção das IFRS: evidências em empresas brasileiras familiares e não familiares

This study aims to determine the influence of the convergence of Brazilian accounting standards to the International Accounting Standards on accounting conservatism of Brazilian familiar and non-familiar companies. Descriptive research with quantitative approach and supported by descriptive research was developed for this purpose. We used the model of Ball and Shivakumar (2005) to measure conditional conservatism. The sample consisted of 315 firms in the period 2003-2012, divided into family and non-family firms. The statistical techniques used in data analysis include the analysis of panel data, the LM test of Breusch-Pagan, VIF, White test and the Durbin-Watson test. The results of the study rejected the hypothesis that the convergence of Brazilian accounting standards to the International Accounting Standards influenced the level of accounting conservatism of Brazilian companies, both to the full sample and the subsample of non-familiar firms. Only for family firms such statistical confirmation was possible. Thus, it is concluded that there is evidence that the adoption of IFRS resulted in an increase in the level of accounting conservatism found in the reports of Brazilian family-controlled companies.
Ultrastructural alterations in human blood leukocytes induced by porcine circovirus type 1 infection

Abstract: Background: Swine infectious pathogens, especially viruses, represent a potential public health risk associated with the use of pig tissues for xenotransplantation in humans. We hypothesized that porcine circovirus type I (PCV‐1) may infect human mononuclear cells, resulting in ultrastructural alterations of the target cells.
Capacity building for sustained competitive advantage: a conceptual framework

Purpose – Capacity building is a crucial antecedent for socio-economic development. However, an enhanced capacity that is difficult to develop could quickly be eroded, because of rapid changes in competitive forces in industries and markets. Therefore, this paper intends to analyse the extant strategic management and relationship marketing (RM) literature that deal with competition. Eventually, the purpose of this paper is to develop an alternative route for capacity building process that could sustain competitive advantage in a market or industry, which encounters rapid changes in business competition. Design/methodology/approach – An inductive constructivist approach is followed to support arguments, in order to develop a synthesis from the relevant literature to reinforce the current understandings on capacity building and sustained competitive advantage. Findings – An influence of RM on strategic organisational dynamic capabilities (DCs) is recognised, which appears as significant to sustain DCs and s.
Streamlined MIMO cross-over digital predistortion

This paper proposes a simplified algorithm for linearizing MIMO nonlinear systems. The linearization technique is designed for MIMO systems with nonlinear cross-talk. The new algorithm relies on estimating the coupling factor and building the 2×2 DPD based on two 1×1 DPDs. The algorithm is around two times faster than the conventional method whilst the performance is reasonably close to the conventional technique.
Physical models of loose soils dynamically marked by a moving object

The paper deals with the modeling of loose soil (sandy, muddy, etc.). When an object moves on such grounds, the object's and the soil's movement both depend on the mutual physical interactions, and therefore are very difficult to achieve with kinematic or geometric models. We use a particle based dynamic modeler and achieve a discrete model of plasticity, which accounts for the influence of the soil on objects moving on this soil, but also for the influence of the object on the movement and the shape of the soil. Thus we have simulated soil compression and piling, vehicles leaving tyre traces spinning, skidding and even sinking. This first step is the simulation of the soil object system at a discretization scale that can be termed "intermediate". A subsequent step consists of the simulation of a finer physical soil model in order to account for smaller scale dynamic phenomena.
String-Level (kW-scale) IV curves from different module types under partial shade

Partial shade is known to cause significant de-rating for most photovoltaic (PV) systems. However, the specific de-rating due to partial shade from differently shaped objects like overhead wires is not well known. We present current-voltage (I-V) curves from three different strings containing 4 to 9 PV modules while applying various types of partial shade, including shade from electrical cables in front of the modules. We show that a 1-kW string of nine poly-Silicon modules manufactured by Sharp can have a power loss of 13% due to shading just 1% of its surface area. We verify that blocking columns of cells in a module has less impact on power loss than blocking rows. This demonstrates how the non-linear response to partial shade can depend on the placement of bypass diodes that isolate different sub-strings within each module. Furthermore, we quantify the reduction in power and I-V parameters caused by shade from wires (or PVC pipes in our experiments).