Miracle-dz/UniFAR-FTUs huggingface dataset:
[Antiviral effect of Folium Isatidis on herpes simplex virus type I].

OBJECTIVE To evaluate the antiviral effect of different chemical fractions isolated from Folium Isatidis on herpes simplex virus type I (HSV- I). METHOD Anti- HSV- I effects of Folium Isatidis were investigated in Hep-2 cell by adopting MTT colorimetric assay and observing cytopathic effect (CPE). Treatment index (TI) was used to evaluate the antiviral activity of different chemical fractions from Folium Isatidis. The antiviral mechanism of Folium Isatidis was investigated by changing the different ways of drug administration. RESULT The fractions II approximately V from Folium Isatidis inactivate HSV- I directly. None of the chemical fractions had antiviral effects of adsorption-blocking. The chemical fractions except fraction III and fraction V inhibited the biological synthesis of HSV- I. The fraction IV significantly reduce death rate of mice infected with HSV- I. CONCLUSION The fraction IV from Folium Isatidis has powerful anti-HSV-lI effect in vitro and in vivo.
Perception of the Effectiveness of Stock Market Recommendations in Relation to Their Real Marketability

The purpose of this paper is to evaluate the effectiveness of stock market recommendations as a factor supporting investment decisions, both in objective and subjective terms. The applicative objectivity of using recommendations is visualized by indicating their real impact on achieving an above‑average return. Subjective utility refers to the perception of recommendations directly by their recipients, including individual investors. For this purpose, a survey was conducted on a group of 564 respondents whose structure is representative of stock market investors in Poland and the results of the survey were verified by conducting statistical analyses (logit models) on the example of selected brokerage houses indicated by investors as the most and least effective in the prediction. The analyses conducted show an ambiguous perception of stock market recommendations by investors. According to investors, the usefulness of stock recommendations issued by individual brokerage houses varies, resulting in different possibilities of generating income using these reports. The responses of respondents to the objective results of investment models using information from stock market recommendations also indicate that individual perceptions of investors’ recommendations do not necessarily translate into their actual usefulness.
PERFORMING VISUAL SURVEYS OF NON-PLANAR BENTHIC TERRAIN

A key issue facing any ROV or AUV-based benthic visual survey is how to point the camera normal to the terrain during the survey. Though planar terrain surveys can be executed using a constant camera orientation, non-planar terrain surveys require that the commanded camera orientation change during vehicle movement. This paper proposes a method that generates a smooth camera orientation command by first spatially filtering local terrain orientation measurements through the construction of a spline-based model of the terrain. The method then calculates an orientation command from the spline model using the spline point projection algorithm. A real-time version of this algorithm has been fielded on a Monterey Bay Aquarium Research Institute ROV, allowing the ROV to maintain camera perpendicularity autonomously over non-planar benthic sites and enabling small-scale visual surveys of these sites.
Conjugated linoleic acid decreases fat accretion in pigs: evaluation by dual-energy X-ray absorptiometry

Thirty female Large White × Landrace pigs (average weight 57·2 (SD 1·9) kg) were allocated to one of six dietary treatments containing 0, 1·25, 2·5, 5·0, 7·5 or 10·0 g 55 % conjugated linoleic acids (CLA) isomers (CLA-55)/kg diet and fed for 8 weeks. Each pig was scanned at 0, 28 and 56 d and again at post slaughter using dual-energy X-ray absorptiometry (DXA) to determine the temporal pattern of body composition responses. Values determined by DXA were adjusted using regression equations generated from validation experiments between chemically and DXA-predicted values. Overall, there was a significant linear reduction in fat content with the increasing levels of CLA in the diet (P=0·007, P=0·011, P=0·008 at week 4, week 8 and for the carcass, respectively). The greatest improvement was recorded at the early stages of CLA supplementation and for the highest dose of CLA (week 4, −19·2 % compared with week 8, −13·7 %). In the first 4 weeks of feeding CLA, pigs receiving 10 g CLA-55/kg diet deposited 93 g less fat/d than pigs fed basal diets (P=0·002) compared with only 6 g less fat than control animals in the final 4 weeks. Lean content and lean deposition rate were maximised at 5 and 2·5 g CLA-55/kg diet for the first 4 weeks (P=0·016) and the final 4 weeks of treatment (P=0·17), respectively. DXA estimates of bone mineral content and bone mineral density were not affected by CLA supplementation throughout the experiment. These data demonstrate that dietary CLA decreases body fat in a dose-dependent manner and that the response is greatest over the initial 4 weeks of treatment.
Notice of RetractionResearch on carbon dioxide emissions of BRICS

With the development of economy, global warming triggered by it is drawing more and more attention. This paper first introduces the BRICS' economic development status and situation of carbon dioxide emissions. And then it analyzes the four countries' Environmental Kuznets Curve and clarifies the relationship between economic development and carbon dioxide emissions. Finally, the paper focuses on policies and measures to control carbon dioxide emissions for China's sustainable development of economy.
[Intracoronary, human autologous stem cell transplantation for myocardial regeneration following myocardial infarction].

OBJECTIVE The regenerative potential of human autologous adult stem cells on myocardial regeneration and neovascularisation after myocardial infarction may contribute to healing of the infarction area. But no clinical application has previously been reported. We here describe for the first time the results of this method applied in a patient who had sustained an acute myocardial infarction. HISTORY AND CLINICAL FINDINGS 14 hours after the onset of left precordial pain a 46-year-old man was admitted to our hospital for interventional diagnosis and treatment. Coronary angiography demonstrated occlusion of the anterior descending branch of the left coronary artery with transmural infarction. This was treated by percutaneous transluminal catheter angioplasty and stent placement. THERAPY AND RESULTS Mononuclear bone marrow cells of the patient were prepared and 6 days after infaction 1,2 infinity 107 cells were transplanted at low pressure via a percutaneous transluminal catheter placed in the infarct-related artery. Before and 10 weeks after this procedure left ventricular function, infarct size, ventricular geometry and myocardial perfusion were measured by (201)thallium SPECT both at rest and on exercise, together with bull's-eye analysis, dobutamine stress echocardiography, right heart catheterisation and radionuclide ventriculography. At 10 weeks after the stem cell transplantation the transmural infarct area had been reduced from 24.6 % to 15.7 % of left ventricular circumference, while ejection fraction, cardiac index and stroke volume had increased by 20-30 %. On exercise the end diastolic volume had decreased by 30 % and there was a comparable fall in left ventricular filling pressure (mean pulmonary capillary pressure). CONCLUSION These results for the first time demonstrate that selective intracoronary transplantation of human autologous adult stem cells is possible under clinical conditions and that it can lead to regeneration of the myocardial scar after transmural infarction. The therapeutic effects may be ascribed to stem cell-associated myocardial regeneration and neovascularisation.
Réduction de dimension en apprentissage supervisé : applications à l'étude de l'activité cérébrale

L'objectif de ce travail est de developper une methode capable de determiner automatiquement l'etat de vigilance chez l'humain. Les applications envisageables sont multiples. Une telle methode permettrait par exemple de detecter automatiquement toute modification de l'etat de vigilance chez des personnes qui doivent rester dans un etat de vigilance elevee (par exemple, les pilotes ou les personnels medicaux). Dans ce travail, les signaux electroencephalographiques (EEG) de 58 sujets dans deux etats de vigilance distincts (etat de vigilance haut et bas) ont ete recueillis a l'aide d'un casque a 58 electrodes posant ainsi un probleme de classification binaire. Afin d'envisager une utilisation de ces travaux sur une application du monde reel, il est necessaire de construire une methode de prediction qui ne necessite qu'un faible nombre de capteurs (electrodes) afin de limiter le temps de pose du casque a electrodes ainsi que son cout. Au cours de ces travaux de these, plusieurs approches ont ete developpees. Une premiere approche propose d'utiliser un pre-traitement des signaux EEG base sur l'utilisation d'une decomposition en ondelettes discrete des signaux EEG afin d'extraire les contributions de chaque frequence dans le signal. Une regression lineaire est alors effectuee sur les contributions de certaines de ces frequences et la pente de cette regression est conservee. Un algorithme genetique est utilise afin d'optimiser le choix des frequences sur lesquelles la regression est realisee. De plus, cet algorithme genetique permet la selection d'une unique electrode.Une seconde approche est basee sur l'utilisation du Common Spatial Pattern (CSP). Cette methode permet de definir des combinaisons lineaires des variables initiales afin d'obtenir des signaux synthetiques utiles pour la tâche de classification. Dans ce travail, un algorithme genetique ainsi que des methodes de recherche sequentielle ont ete proposes afin de selectionner un sous groupes d'electrodes a conserver lors du calcul du CSP.Enfin, un algorithme de CSP parcimonieux base sur l'utilisation des travaux existant sur l'analyse en composantes principales parcimonieuse a ete developpe.Les resultats de chacune des approches sont detailles et compares. Ces travaux ont aboutit sur l'obtention d'un modele permettant de predire de maniere rapide et fiable l'etat de vigilance d'un nouvel individu.
The impact of manufacturing industries on Ghana’s economy

Ghana’s economic growth over the last decade has been among the most rapid in Africa and faster than in some high investment emerging market economies. The economy of Ghana has experienced moderate but consistent growth over the past 25 years, with growth rate between 1990 and 2010 averaging 5 percent. Industry in Ghana accounts for about 25.3% of total GDP. However, Ghana's industrial production is rising at a 7.8% rate, giving it the 38th fastest growing industrial production in the world due to government industrialization policies. Currently, it is estimated that the average medium-term real GDP growth rate in Ghana would be at least 8% per annum. Currently, Ghana’s industrial sector after the rebasing of the national account estimates in November 2010 consists of five sub-sectors namely; Manufacturing, Construction, Mining and Quarrying, Electricity, Water and Sewerage. Prior to the rebasing, the electricity and water and sewerage sub-sectors had been lumped together. The key objective of the study is to examine the factors that affect the competitiveness of local industries highlighting both the internal and external constraints. Questionnaires were used as the main instrument for primary data collection from the respondents. Also, various questions under each objective were analyzed systematically using the one sample t-test presented in tables and graphs (SPSS and Excel). In addition, Michael Porter’s Theory was used to analyze the competitiveness of local manufacturing industries in Ghana. Lastly, logical inferences and interpretations were made out of the resultant data.
Development of a novel tablet-in-capsule formulation of mesalamine for inflammatory bowel disease

Objective: The objective of the present work was to develop a tablet-in-capsule type of multiunit system, which releases the drug in a controlled manner at pre-programmed time intervals. Methods: The system consists of an enteric-coated hydroxypropyl methylcellulose capsule filled with four units of mesalamine minitablets, each of which was further coated with different ratios of Eudragit® E100 and Eudragit® RS100. Results: In vitro evaluation of tablets coated with Eudragit® E100 and Eudragit® RS100 at different pH conditions revealed that at lower pH levels (2.0, 3.6 and 5.5 pH), the drug release is mainly governed by the dissolution of Eudragit® E100 from the Eudragit® E100 and Eudragit® RS100 coat. In vitro evaluation of capsules enteric coated with Eudragit® L100 and Eudragit® S100 revealed that a maximum lag time of 3 h and 4 h was obtained, respectively. In vivo roentgenographic evaluation in rabbits revealed that the developed system remained intact until it reaches the targeted region of the gastrointestinal tract, i.e. ileum and colon, where the tablets were released after the dissolution of the enteric coat Eudragit® L100 and Eudragit® S100, respectively. Conclusion: The developed system exhibited a promising targeting behavior and hence may be used for the treatment of inflammatory bowel disease.
Stimulations spécifiques pour la rééducation de déficits moteurs : biomécanique et modélisation

Notre travail de these s'est attache a comprendre les mecanismes mis en jeu par une experience d'adaptation visuomanuelle inspiree de l'adaptation saccadique, qui a ete decrite par [Magescas 2006a]. Le premier chapitre visait a montrer que le paradigme de [Magescas 2006a] induisait peu ou pas d'effets sensoriels. Dans le deuxieme chapitre, nous nous sommes interesses au processus exact de generalisation de l'adaptation au niveau de la seule articulation du coude. Nos resultats nous permettent d'avancer l'idee que le paradigme etudie induisait une modification specifique du gain moteur pour le groupe de muscles extenseurs du coude. Le troisieme chapitre presente le developpement de methodes d'enregistrement de la chaine articulaire du membre superieur. Cette methodologie a permis une comparaison precise entre des hypotheses de generalisation de l'adaptation dans l'espace des tâches et dans l'espace articulaire. Dans un quatrieme chapitre, suivant une demarche exploratoire, nous avons imagine deux protocoles de transposition de l'experience de [Magescas 2006a], afin d'elargir nos possibilites pour une future etude sur des patients ayant un deficit moteur. A l'issue de ce travail, nous disposons a la fois : de moyens methodologiques pour l'enregistrement et la modelisation de la chaine articulaire du membre superieur ; d'un modele theorique du fonctionnement de l'adaptation motrice etudiee ; et d'un protocole d'adaptation de la saisie, mieux adapte a la clinique que le protocole d'adaptation du pointage.
The RTEL 1 rs 6010620 Polymorphism and Glioma Risk : a Meta-analysis Based on 12 Case-control Studies

Gliomas are central nervous system neoplasms derived from glial cells that surround and support neurons (Liu et al., 2007). Gliomas account for approximately 80% of central nervous system malignant tumors and have a very poor prognosis (Schoemaker et al., 2010; Walsh et al., 2013b). Although the etiology of gliomas remains unclear, exposure to ionizing radiation has been identified as the only established risk factor (Little et al., 1998; Neglia et al., 2006). Glioma is associated with considerable morbidity and mortality, and occurs more often in males than in females (Chen et al., 2012). In the past decade, many investigators have explored factors that contribute to inherited glioma susceptibility. Up to date previous published articles found that many gene variations may associate with glioma risk, such as XRCC1 mutations, XRCC3 mutations, IDH mutations etc. The gene polymorphisms increased or decreased glioma sensibility by regulating the proliferation and apoptosis of cells (Das et al., 2013; Liang et al., 2013). (Das et al., 2013; Li et al., 2013b) They revealed that gene mutations may contribute to the occurrence of glioma. Sequence variants in RTEL1 gene regions are associated with
Amazing Machines and the Quest for Meaning in Consumption

Abstract The benefits brought to us by recent product innovations also come with potential burdens for people who are motivated to consume by identity motives - that is, by the desire to be the kind of person that they want to be. Being freed from a personally relevant routine might be undesirable. Therefore, IoT adoption will be more likely when the associated tasks are less relevant for identity signaling and less likely when the associated tasks are relevant for one’s identity. However, people who oppose IoT application in one context might willingly accept IoT applications in others with less personal relevance. Managers should not overlook that people’s quest for meaning in consumption remains an important driver of buying decisions even in our age of amazing machines. Physical products won’t completely disappear any time soon, especially when they are relevant for a person’s identity.
Sandfly Virus Encephalitis in Israel: Two Case Reports and a Review

Background: Infections due to Sand-fly virus (SFV) are common in the Mediterranean region, but are rarely diagnosed in Israel. Until recently, no cases of severe neuro-invasive SFV infections were reported. In this study, we describe two cases of encephalitis associated with seroconversion to SFV acquired in Israel. We further try to postulate about the infecting strain of the SFV, its local phlebotomine vector, and the reasons for the emergence of this infection in Israel. Methods: Clinical data were collected from hospital records. Laboratory diagnosis was obtained using mosaic indirect immunofluorescence tests (IFT) against several SFVs. Results: Two patients with severe encephalitis presented during the same 2014 summer season. Both have acquired their infection in Hasharon district of central coastal Israel. Their encephalitis developed after a prolonged prodrome of 7 and 14 days, and was associated with severe neurological complications. Both patients exhibited a late seroconversion beyond twenty days from symptom onset. Conclusion: SFVs are possible etiological agents of febrile illnesses and central nervous system infections in Israel. The SFV we report is suspected to be a Toscana virus-like strain, and is probably transmitted by Phlebotomus perfiliewi. A review of the spread of phlebotomine vectors is presented.
Synthesis of Strategies in Influence Diagrams

Inﬂuence diagrams (IDs) are a powerful tool for representing and solving decision problems under uncertainty. The objective of evaluating an ID is to compute the expected utility and an optimal strategy, which consists of a policy for each decision. Every policy is usually represented as a table containing a column for each decision scenario, i.e., for each conﬁguration of the variables on which it depends. The no-forgetting assumption, which implies that the decision maker always remembers all past observations and decisions, makes the policies grow exponentially with the number of variables in the ID. For human experts it is very difﬁcult to understand the strategy contained in huge policy tables, not only for their size, but also because the vast majority of columns correspond to suboptimal or impossible scenarios and are hence irrelevant. This makes it difﬁcult to extract the rules of action, to debug the model, and to convince the experts that the recommendations of the ID are reasonable. In this paper, we propose a method that presents the strategy in the form of a compact tree. It has been implemented in OpenMarkov, an open-source software tool for probabilistic graphical models. This facility was essential when evaluating an inﬂuence diagram for the mediastinal staging of non-small cell lung cancer; the optimal strategy, whose biggest policy table contained more than 15,000 columns, was synthesized into a tree of only 5 leaves.
Barriers to access to abortion through a legal lens.

In addressing whether the procedure for obtaining abortions was operating equitably across Canada, the 1977 Badgley Report concluded that for many women, access to abortion was "practically illusory. " Sadly, although abortion on request became legally permissible for Canadian women in 1988, access to a safe and legal abortion remains practically illusory for many women today. A woman seeking an abortion in Canada must overcome numerous barriers. She must find a way to secure for herself some of the limited resources that our health care system provides for abortion. She must also expend her own, often scarce, personal resources: her time, her money, and her emotional energy. Access is also compromised by other factors such as the lack of information, support, and privacy.In this paper, we will examine both legal and non-legal barriers to abortion through a legal lens. That is, we will provide a comprehensive description of the multitude of systemic, personal and other barriers that have been identified in various places in the literature and then explore ways in which law could be used to deconstruct these barriers. The ultimate goal is to contribute to the development of legal strategies aimed at achieving meaningful access to abortion for all women in Canada.
Soma and axon diameter distributions and central projections of ferret retinal ganglion cells

Abstract Using a combination of retrograde horseradish peroxidase (HRP) labelling, silver staining, and electron microscopy, we have assessed the relationship between retinal ganglion cell soma size and axon diameter in the adult ferret (Mustela putorius furo). Retinal ganglion cells were labelled following injections of HRP into the lateral geniculate nucleus (LGN), superior colliculus (SC), or LGN+SC. The soma size distributions following LGN, SC, or LGN+SC injections were all unimodal showing considerable overlap between different cell classes. This was confirmed for alpha cells, identified on the basis of dendritic filling or from neurofibrillar-stained retinae. Analysis of the soma size and axon diameters of a population of heavily labelled retinal ganglion cells showed a significant correlation between the two. However, the overall distribution of intraretinal axon diameter was bimodal with an extended tail. Analysis of the ganglion cell distributions in the adult ferret indicates that beta cells comprise about 50.5–55%, gamma 42.5–47%, and alpha 2.5% of the ganglion cell population. This implies that the proportion of gamma, beta, alpha cells in both cat and ferret retina is highly conserved despite differences in visual specialization in the two species.