Miracle-dz/UniFAR-FTUs huggingface dataset:
Matrix metalloproteinase 9 polymorphism and outcome after myocardial infarction

Matrix metalloproteinase 9 (MMP9) is functionally implicated in the process of infarct healing. Several genetic variation of the MMP9 gene have been described, among which the MMP9 Arg668Gln polymorphism. In the present study, we assessed whether this polymorphism influences outcome after acute myocardial infarction (MI). One thousand forty-nine patients undergoing coronary angiography were genotyped for the MMP9 Arg668Gln polymorphism by TaqMan allelic discrimination assay. This population included 154 controls, 161 patients with non ST-elevation MI (NSTEMI), 504 patients with ST-elevation MI (STEMI), and 230 patients with angina. Frequency of the MMP9 Arg668Gln polymorphism in the global population was 25.1%, and was comparable between all groups. STEMI patients had higher creatine phosphokinase (CPK), troponin T (TnT) and MMP9 plasma levels and had lower ejection fraction (EF) than NSTEMI patients. However, the polymorphism was not associated with infarct severity as determined by peak CPK and TnT levels, nor with LV remodeling and outcome as assessed by 1-month EF and NYHA class, as well as 2- year mortality. In silico molecular modeling simulations predicted that the MMP9 polymorphism may decrease MMP9 activity, but this could not be verified by plasma determinations. This study investigated for the first time the association between the MMP9 Arg668Gln polymorphism and clinical outcome after acute MI. Our results indicate that the polymorphism does not seem to be associated with clinical outcome and in particular with the development of left ventricular dysfunction and heart failure.
En torno a la arquitectura doméstica sevillana del siglo XIX: el paso del neoclasicismo a la arquitectura isabelina

espanolLa arquitectura domestica sevillana inicia el siglo XIX manteniendo muchos de los elementos propios del anterior aunque poco a poco va evolucionando hacia otros mas clasicos, menos ornamentados, menos barrocos generando un aspecto mas severo con la utilizacion de frontones rectos pilastras lisas. A partir de 1825, los arquitectos procedentes de la Real Academia de San Fernando imponen un tipo de fachada neoclasica al modo villanovino. En la segunda mitad del siglo se dio un tipo de palacio de clara raigambre francesa cuyo mejor exponente es la Casa de las Sirenas. Ademas de las construcciones destinadas a las clases pudientes surge un tipo de viviendas para el proletariado en las que se primaron la optimizacion del espacio y, a veces, los aspectos higienicos. EnglishSeville’s domestic architecture began the 19th century preserving most of own components of previous century however changing to others that could be considered more classical, less embroidered and less baroque, developing serious appearance due to straight pediments and flat pilasters utilization. From 1825, a kind of neoclassical facade (villanovino style) is imposed by architects coming from “Real Academia de San Fernando”. In the second half of the century a kind of french-style palace can be founded and “Casa de las Sirenas” is best model. Besides wealthier classes constructions, a new kind of houses for proletariat is going to be appeared where space’s optimization and sometimes healthy conditions have been prioritized.
Hypertension in blacks: Epidemiology, pathophysiology, and treatment

Why should wait for some days to get or receive the hypertension in blacks epidemiology pathophysiology and treatment book that you order? Why should you take it if you can get the faster one? You can find the same book that you order right here. This is it the book that you can receive directly after purchasing. This hypertension in blacks epidemiology pathophysiology and treatment is well known book in the world, of course many people will try to own it. Why don't you become the first? Still confused with the way?
A virtual sculpture based morphable face model

A Virtual Sculpture Based Morphable Face Model. (May 2007) Jessica Lauren Riewe, B.S., Texas A&M University Chair of Advisory Committee: Dr. Frederic Parke Exemplar virtual three-dimensional sculptures collected from sixteen artists are used to develop a multidimensional space to describe facial shape, which is then used as a mechanism for modeling new faces. This is accomplished through identifying and varying derived principal components of the multi-dimensional space. The relationships between these principal components and their effects on new faces are explored through the creation of new virtual faces using a graphical user interface. These new virtual face sculptures are then modified by facial feature, gender, and expression using a feature-based transformation interface based on difference vectors. Finally, animations are created to illustrate the results of these approaches. Facial mesh transformations based on principal components does not give direct predictable control for modifying specific facial features. However, it does provide interesting design choices for artists, and general patterns of the data variance were obtained. The feature-based transformations were successful in further modifying created faces.
Effects of linguistic variance on sound-meaning connections in early stages of language acquisition

To explore the processes underlying early sound-meaning connections an artificial language was created and used in a series of infant speech perception studies. The subjects were tested using the Visual Preference Procedure. The subjects’ responses were quantified in terms of looking times towards objects shown during the audio-visual exposure. Exposure to speech materials with large variance seemed to curtail the subjects’ ability to establish stable sound-meaning connections. However, reducing the linguistic variance led to successful sound-meaning connections. These results indicate that linguistic variance is one of the primary determinants of sound-meaning connections for 1-year old subjects. The paper will discuss how structural differences in natural language settings may account for the infant’s performance on word learning.
Freelance Counselling and Psychotherapy : Competition and Collaboration

The Development and Growth of Freelance Counselling and Psychotherapy. The Internal Dynamics of Working Freelance. Starting in Private Practice. Regulation, Registration and Accreditation. Some Issues. Sorting out Supervision. The Unspoken Relationship. Financial Dynamics in Freelance Therapy. The Loneliness and Freedoms of Change. A Therapist in the Family. Personal and Professional Development. The Early Years. Experiences of Recently Qualified Counsellors. Working in Primary Care. Working with Employee Assistance Programmes. Working from Home - A Psychotherapist With Long Term Clients.
A new mobile digital radio transceiver concept using low-complexity combined equalization/trellis decoding and a near-optimal receiver sync strategy

For land-mobile digital radio links over time-variant frequency-selective multipath channels, power and bandwidth efficient signaling and time diversity, as provided by interleaved trellis-coded modulation, are of great importance in a fading environment. A novel digital radio transceiver concept is presented that encompasses interleaved trellis coded modulation with large time diversity factor, a combined equalization/decoding scheme, and a quasi-optimal receiver sync strategy based on purely feedforward channel estimation. The resulting fully coherent and robust receiver is of remarkably low computational complexity. The average BER performance of such a transceiver operating over flat and selective 2-ray Rayleigh as well as typical land-mobile GSM channels is assessed via simulation. The results reveal the receiver's robustness and good BER performance and also shed light on the effects of insufficient interleaving at low vehicle speeds. <<ETX>>
The Effect of Touch-key Size and Shape on the Usability of Flight Deck MCDU

This paper focuses on the effect of touch-key size and shape on the usability of the multifunction control display unit (MCDU) of the flight deck. A total of thirty subjects participated in the trials on the touchscreen-MCDU to perform the task of preflight preparation. The sizes of the touch-key were 7mm, 10mm, 13mm, 16mm, 19mm and 22mm; the touchkeys were divided into two shapes: rectangle and square ones. The completion time of the task, the error rate and participants’ subjective ratings were collected as the indicators of the usability, and Analysis of Variance (ANOVA) was done to test the data. Results showed that both touch-key size and shape affected the usability. The usability of the touchscreenMCDU increased as the touch-key size increased up to a certain size (19 mm in this study), at which they reached asymptotes. The square touch-keys provided a better usability than the rectangle ones when the width was the same. However, when the width reached 19mm, the usability stayed the same
Does Early Treatment of Urinary Tract Infection Prevent Renal Damage?

OBJECTIVE. Therapeutic delay has been suggested as the most important factor that is likely to have an effect on the development of scarring after acute pyelonephritis. However, this opinion has not been supported by prospective studies, so we tested it. METHODS. In a prospective clinical study, we evaluated whether the time interval between the onset of the renal infection and the start of therapy correlates with the development of acute inflammatory changes and the subsequent development of renal scars, documented by dimercaptosuccinic acid scintigraphy. A total of 278 infants (153 male and 125 female) aged 0.5 to 12.0 months with their first urinary tract infection were enrolled in the study. RESULTS. The median time between the onset of infection and the institution of therapy was 2 days (range: 1–8 days). Renal inflammatory changes were documented in 57% of the infants. Renal defects were recorded in 41% of the patients treated within the first 24 hours since the onset of fever versus 75% of those treated on day 4 and onward. Renal scarring was developed in 51% of the infants with an abnormal scan in the acute phase of infection. The frequency of scarring in infants treated early and in those whose treatment was delayed did not differ, suggesting that once acute pyelonephritis has occurred, ultimate renal scarring is independent of the timing of therapy. Acute inflammatory changes and subsequent scarring were more frequent in the presence of vesicoureteral reflux, especially that which is high grade. However, the difference was not significant, which suggests that renal damage may be independent of the presence of reflux. CONCLUSIONS. Early and appropriate treatment of urinary tract infection, especially during the first 24 hours after the onset of symptoms, diminishes the likelihood of renal involvement during the acute phase of the infection but does not prevent scar formation.
Plural morphology in compounding is not good evidence to support the dual mechanism model

The compounding phenomena is considered to be good evidence to support the dual mechanism model of morphological processing (Pinker & Prince, 1992). However evidence from initial neural net modeling has shown that a single route associative memory based account might provide an equally, if not more valid explanation of the treatment of plurals in compounds. Further neural net modeling and empirical work is proposed to test this single route account.
Analiza adaptacyjnego neuronowo rozmytego regulatora z wykorzystaniem konkurencyjnych warstw typu Petriego w sterowaniu silnikiem prądu stałego

W artykule przedstawiono zagadnienia zwi zane z zastosowaniem adaptacyjnej struktury sterowania z przestrajalnym regulatorem neuronowo rozmytym, dla uk adu nap dowego o nieznanym momencie bezw adno ci. Zastosowano adaptacyjn struktur sterowania z modelem odniesienia. Regulator neuronowo – rozmyty zmodyfikowano poprzez wprowadzenie konkurencyjnej warstwy Petriego. Zmiana taka pozwoli a na popraw w a ciwo ci dynamicznych uk adu nap dowego z silnikiem pr du sta ego w porównaniu do klasycznego regulatora neuronowo rozmytego. Rozwa ania teoretyczne zosta y potwierdzone przez badania symulacyjne wykonane w pakiecie SimPower system.
Favourable Outcome After Resection for Contained Malignant Colorectal Perforation

Background: Perforation in colorectal cancer occurs due todirect perforation from or from proximal colon rupture. This study was aimed at documenting our experience with malignant colorectal perforation and to establish trends in presentation. Analysis of ongoing database of all patients with colorectal cancer in the KwaZulu-Natal State Hospitals established since 2000 was undertaken. The Setting was the Colorectal Unit in a tertiary centre Patients: All patients with malignant perforation were extracted from the database and analyzed. Data collected included demographics, presentation, treatment, outcome, and follow-up. The main outcome measure was the In-hospital mortality Results: By the end of 2012, the database was then comprised 1425 patients, of whom 48 (3.4%) were found to have malignant perforation. The Male-to-female sex ratio was 1:1, and age (mean + SD) was 54.5+ 15.6 years. Perforation occurred in 3%, 2%, 4%, and 5% of Africans, Indians, Coloureds, and Whites respectively. The disease distribution was right colon (15), descending colon (5), hepatic flexure (1), sigmoid (21), and rectum (6). Twelve patients with intestinal obstruction required emergency resection (25%). The rest underwent elective resection with the perforation discovered either at operation or at histopathologic analysis. One, 19, 23, 5 patients had Stage I, II, III, and IV respectively. There was no postoperative mortality. Only 6 patients had early disease and were deemed not to require adjunctive or palliative therapy. Patients were followed up for 14.6 + 19 (range 1-94) months. Seven patients were lost to follow up, and two are confirmed dead. Up to now four of the 39 evaluable patients have developed metastases. Limitation: Inadequate follow-up data Conclusion: Malignant perforation occurs in about 3% of colorectal cancers in our geographical area of Southern Africa. The sex distribution and prevalence is the same in all population groups. Disease distribution follows general norms. Interestingly the perforation rarely leads to peritonitis. There was no postoperative mortality in this cohort. This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source (including a link to the formal publication), provide a link to the Creative Commons license, and indicate if changes were made.
Suggesting Relevant Queries Based on Transition Probability of Information in Web Graphs

Query suggestion is an important process in the case of a search engine to predict the user’s information needs. In many cases, we can generate the relevant prediction from large scale Web graphs containing queries and other related information like clickthrough data generated by the search engine. However generating suggestion based on the semantic relevancy with the user’s information need is a challenging problem. In this paper, a modification of the general query suggestion technique is proposed which is based on queryURL graph based on the clickthrough data generated by the search engine. Here the transition probability of information between nodes in the graph is taken as the parameter to suggest relevant queries. Based on this, a sub graph is constructed by short random walk on the graph and the basic heat diffusion equation is applied in the sub graph to suggest the relevant queries. Also the complexity of the existing query suggestion algorithm based on the heat diffusion equation is reduced by this approach. KeywordsQuery suggestion, transition probability, diffusion
A handbook to twentieth-century musical sketches

Introduction Friedemann Sallis and Patricia Hall 1. Sketches and sketching Giselher Schubert and Friedemann Sallis 2. Preliminaries before visiting an archive Ulrich Mosch 3. Archival etiquette Therese Muxeneder 4. Coming to terms with the composer's working manuscripts Friedemann Sallis 5. The classification of musical sketches exemplified in the catalogue of the Archivio Luigi Nono Erika Schaller 6. Digital preservation of archival material William Koseluk 7. Transcribing sketches Regina Busch 8. A tale of two sketchbooks: reconstructing and deciphering Alban Berg's sketchbooks for Wozzeck Patricia Hall 9. 'Written between the desk and the piano': dating Bela Bartok's sketches Laszlo Somfai 10. Defining compositional process: idea and instrumentation in Igor Stravinsky's Ragtime (1918) and Pribaoutki (1915) Tomi Makela 11. Floating hierarchies: organisation and composition in works by Pierre Boulez and Karlheinz Stockhausen during the 1950s Pascal Decroupet 12. Elliot Carter's sketches: spiritual exercises and craftsmanship Denis Vermaelen 13. E-Sketches: Brian Ferneyhough's use of computer assisted compositional tools Ross Feller 14. John Cage's Williams Mix (1951-3): the restoration and new realizations of and variations on the first octophonic, surround-sound tape composition Larry Austin Appendix. Select list of institutions housing manuscript collections of twentieth-century composers.
Svensk normering av TROG-2 för åldrarna 8-10 år och sambandet mellan grammatisk språkförståelse och ordavkodning

The main purpose of this study was to collect norm data for the grammatical receptive language test Test for Reception of Grammar Version 2 (TROG-2), from 144 Swedish children, aged 8:0-9:11 years. Another aim was to investigate whether a change in the order of the blocks was needed in the Swedish version of TROG-2 to keep an increasing level of difficulty. Other aims included to investigate the relationship between receptive grammar and word decoding, and between parents ratings of their children’s language comprehension and reading abilities and the children’s results on the TROG-2 and a word decoding test. The results showed that the order of the blocks needs to be changed and that there was no significant relationship between language comprehension and word decoding. Parents were better at rating their children’s reading than language comprehension.
7 Simulation Approaches to Intelligent Vehicles

The development of systems for intelligent functions is a very complex process, involving many technological components, requirements with respect to robustness and fail safety, time pressure, and different stakeholders. Simulation plays an important role in the development process and can support the development process from the early concept development, through testing and verification of components to the validation and evaluation of systems. Requirements and examples of simulation environments needed are discussed. Traffic flow simulation is used to show how it can be used in the development of the concept of Cooperative Adaptive Cruise Control. Next, simulation is applied for testing and verification of cooperative safety applications. Finally, simulation is applied for validation and evaluation of applications tested in a Field Operational Test.
Gesturecraft: The manu-facture of meaning

1. Acknowledgments 2. 1. Manufactured understanding 3. 2. Gesture as interaction: On methodology 4. 3. Hands 5. 4. Gathering meaning 6. 5. The turn to the hands 7. 6. Depicting 8. 7. Thinking by hand 9. 8. Speech-handling 10. 9. A sustainable art 11. Appendix 12. Bibliography 13. Person index 14. Subject index 15. Video clips
Studies on growth in organ culture of testicular tissue from rats of various ages

Testicular fragments from newborn, 4, 14, 24, 37‐day old and mature rats were cultured using a modification of Trowell's method. Eagle's medium supplemented with amino acids, Na‐pyruvate and 10% calf serum was employed. Tissue fragments were fixed at time intervals for histologic study. In cultures of fragments from newborn and four‐day rats, gonocytes persisted and showed mitotic activity. In fragments from older but still immature animals, gonocyte‐like cells occasionally undergoing mitosis, appeared in the germinal epithelium after the fourth day in culture. Spermatocytes survived for approximately four weeks. More rapid degeneration of the germinal elements beyond spermatogonia was observed in cultures of mature testes. During the first six days in culture, cells resembling gonocytes, some in mitosis, appeared in the tubules. The studies have shown that under the conditions employed, Sertoli cells and gonocyte‐like could be maintained for at least four months in cultured fragments of testes from animals of various ages. In fragments from older animals, gonocyte‐like cells appeared shortly after initiation of culture while the more mature germinal elements ultimately degenerated.
Vascular Injury and Delayed Hemorrhage after Antebrachial External Skeletal Fixation in a Dog

Summary A seven-month-old female Saluki was diagnosed with angular limb deformity due to premature closure of the left distal ulnar physis. Corrective radial osteotomy and ulnar ostectomy were performed, and the radius was stabilized with external skeletal fixation. Profuse haemorrhage occurred from the second medioproximal pin site two weeks after surgery. Removal of the pin resolved the hemorrhage. Early recognition and treatment of vascular injury secondary to vessel erosion after external skeletal fixation is necessary, as this is a serious complication. Appropriate pin placement in the radius will prevent this complication. Two weeks after application of an external skeletal fixator to the antibrachium of a seven-month-old Saluki profused haemorrhage occurred from one pin site. Surgical removal of the pin was necessary to arrest haemorrhage.
Solving large‐data consistency problems at Statistics Netherlands using macro‐integration techniques

The generalized multivariate Denton model for achieving consistency between large accounting frameworks developed at Statistics Netherlands (SN) is originally intended for benchmarking of supply and use (SU) tables of national accounts. The success of this application in the production process triggered using the model for other processes within the office. Currently, at SN, many production processes of national accounts, but also other departments, use the modifications of this optimization model for achieving consistency of data obtained from different sources. These include reconciliation and benchmarking of SU tables and of institutional sector accounts, ESA (European system of accounts), revisions of SU tables, benchmarking of gross fixed capital formation, Population Census tables, and energy statistics figures. The mathematical model is based on a quadratic optimization function and combines different features, such as linear constraints, ratio constraints, weights, soft and hard constraints, and inequalities. The optimization problems we deal with can be very large, consisting of 500,000 variables and over 100,000 constraints. This optimization problem is solved using the commercially available software tool XPRESS and the free software tool R. For the reconciliation of trade and transport statistics, similar optimization techniques are used. In this paper, we give an overview of production processes at SN using macro‐integration techniques.