Miracle-dz/UniFAR-FTUs huggingface dataset:
Design and development of a two-phase closed loop thermosyphon for CPU cooling

Regarding the use of micro-structured surfaces, the micro-patterns consist of arrays of laser etched cavities, with fixed shape and dimensions, so the sole varying parameter is the distance between cavities. The results show that the overall thermal resistance is reduced 21% using the surface with cavities distance of 300μm, when compared to the performance evaluated for a smooth surface. In transient power steps, the onset of nucleate boiling was identified as the critical parameter influencing the system performance, due to the overshoot in the temperature above steady-state values.
SwissPeaks-Mobile augmented reality to identify mountains

The paper describes the implementation of SwissPeaks, a mobile augmented reality application for identifying mountains on Apple’s iPhone 3GS. The presented prototype includes a novel approach for correcting inaccurate sensor data with manual user input and uses a web service to display only mountains which are actually visible from the user’s point of view.
Use of Oxygen Carriers to Promote Islet Engraftment in Extravascular Sites.

The field of islet transplantation has made extraordinary progress in the last 2 1/2 decades. After the standardization of islet isolation techniques and through careful attention to isolation parameters, it has been well established that a large number of islets frommultiple donors can provide years of insulin independence in some recipients. More recent data suggest that the introduction of anticytokine agents has improved engraftment success, such that some experienced centers are reporting 5-year insulin independence rates of 50%or more, a conceptual, if not actual, watershed. In this issue of Transplantation, Espes et al take a new look at an old problem that continues to plague islet transplantation; that is, promoting better cell engraftment in a conveniently accessible site.Many agree that a viable alternative to the intrahepatic infusion of islets could provide the next major step forward in graft functional outcomes. The intraportal site is used as the route for clinical islet transplantation, despite the description of an inflammatory and thrombotic response to the infused tissue, a process known as immediate blood-mediated inflammatory response, consumes a large proportion of the transplanted β-cell mass. To compound this, islets remain at a subphysiologic oxygen tension provided by the portal circulation, until neovascularization and capillary ingrowth take place. The combined effects of these injuries are likely the primary explanation for the lag in transplant outcomes in the past, compared to whole pancreas transplantation. Despite the significant cell loss associatedwith intrahepatic islet infusion, an easily accessible alternative to this site, where islets can engraft well, has not been found to date. Islets transplanted into nonvascularized spaces are prone to suffer primary graft failure due to hypoxia and fibrosis. This is due to the fact that neovascularization to the core of the islet may take days to weeks to occur. Furthermore, isolated human islets are known to elaborate a variety of hypoxic signals and chemokines, among them interleukin-8 and monocyte chemoattractive protein-1, which can stimulate production of collagen type 1 by fibroblasts and increase local expression of fibrogenic TGF-β and collagen production in the area around the implanted islets.
Boundary driven Markov gas: duality and scaling limits

Inspired by the recent work of Bertini and Posta, who introduced the boundary driven Brownian gas on $[0,1]$, we study boundary driven systems of independent particles in a general setting, including particles jumping on finite graphs and diffusion processes on bounded domains in $\mathbb{R}^d$. We prove duality with a dual process that is absorbed at the boundaries, thereby creating a general framework that unifies dualities for boundary driven systems in the discrete and continuum setting. We use duality first to show that from any initial condition the systems evolve to the unique invariant measure, which is a Poisson point process with intensity the solution of a Dirichlet problem. Second, we show how the boundary driven Brownian gas arises as the diffusive scaling limit of a system of independent random walks coupled to reservoirs with properly rescaled intensity.
Percutaneous Mitral Valve Repair of Mitral Valve Prolapse using Mitraclip

Background: Chronic mitral regurgitation can be divided into primary and secondary. The most common cause of chronic primary mitral regurgitation in developed countries is mitral valve prolapse. Many patients remain asymptomatic for quite some time, although its presence has an impact on the prognosis that is why it is mandatory to be address appropriately. In patients with chronic symptomatic, severe mitral regurgitation from degenerative cause, surgical mitral valve repair remains the gold standard. However, percutaneous mitral valve repair has been in progress in different countries and it has shown propitious result. Mitraclip restores leaflet coaptation by approximating the edges of the regurgitant mitral valve leaflets under transesophageal echocardiography and fluoroscopic guidance. Case: This is a case of a 61year old male, hypertensive, who came in for routine checkup prior to endoscopy which showed severe mitral regurgitation from posterior mitral valve prolapse three years ago. He was given the option to undergo surgical versus transcutaneous repair of the mitral regurgitation but opted to be treated medically. Four months prior to consult patient underwent emergency ventriculo-peritoneal shunting and coil embolization secondary to left posterior cerebral artery aneurysm. He was discharged improved with no residual deficit. Afterwards, the patient reconsidered the choice of mitraclip. Diagnostics and therapeutics: Work-up done to the patient revealed moderate coronary artery disease of the ramus intermedius and severe mitral regurgitation secondary to posterior mitral valve prolapse for which he underwent percutaneous mitral clip. Conclusion: The successful performance of mitraclip in our institution offers our future patients an alternative to surgical repair or replacement. It is comparable to surgery in terms of reducing the left ventricular volume, dimension and mitral gradient. Correspondence to: Francis Carl L. Catalan, Cardiology Research Fellow, Section of Invasive Cardiology, Cardinal Santos Medical Center, Philippines; E-mail: franciscarlmd@gmail.com
Using Twitter as a Source for Travel Warnings : the Role of Information Source and Target Audience

Business travelers are oftentimes equipped with technology informing them about local dangers. As these corporate travel risk applications increase personal safety during travels, they are also expensive and hardly available to the average traveler. Online platform Twitter, known for extensive contribution by nonaffiliated users, has also been recognized by international foreign offices as an outlet for travel warnings and guidance. This new channel of information allows for the creation of applications that bring current and high quality travel risk information to the mainstream. Our explorative research aims at investigating the role of the information source and target audience of such an application. The results of our analysis show no substantial evidence that user-generated travel risk information would be per se unsuitable as an information source. Further, our analysis revealed that frequent travelers as well as non-frequent Twitter users might be of special interest as a target group for the application.
ELENA PIURKO DISCOURSE MARKERS : THEIR FUNCTION AND DISTRIBUTION IN THE MEDIA AND LEGAL DISCOURSE

4 INTRODUCTION.5 1. ON THE CONCEPT OF DISCOURCE. 9 1.1 Discourse and discourse analysis.9 1.1.1 The spoken and written discourse.11 1.2 The notion of genre . 12 1.4 Cohesion and coherence.13 2. DISCOURSE MARKERS.15 2.1 Definition and classification of discourse markers.16 2.2 Isomorpic features of discourse markers.19 2.3 Functional domains.22 2.3.1 The textual function of discourse markers.24 2.3.2 The interpersonal function of discourse markers.25 3. DISCOURSE MARKERS ACROSS GENRES.29 3.1 Discourse markers in the editorials.29 3.2 Discourse markers in the interviews.37 3.3 Discourse markers in the conventions.49 3.4 Discourse markers in the trials.52 4. COMPARISON OF FORMS AND FUNCTIONS OF DISCOURSE MARKERS.59 4.1 Discourse markers in the textual functions.62 4.2 Discourse markers in the interpersonal functions.65 CONCLUSIONS.68 SUMMARY.70 REFERENCES.71 APPENDIX.74
Efficacy of adjunct tacrolimus treatment in patients with rheumatoid arthritis with inadequate responses to methotrexate

ObjectivesWe aimed to assess the efficacy of tacrolimus (TAC) as an add-on therapy in patients with rheumatoid arthritis (RA) who were previously treated with methotrexate (MTX) but not with biologics.MethodsThe study group (MTX + TAC group) consisted of 157 patients (selected from among the patients in the Institute of Rheumatology, Rheumatoid Arthritis [IORRA] RA cohort from April 2005 to October 2009) who received add-on therapy with TAC in addition to MTX, but without biologics. A propensity score (PS) for the use of TAC was derived, and 471 PS-matched patients who received MTX alone or MTX with other non-biologic disease-modifying antirheumatic drugs (except for TAC), but not with biologics, were selected and served as the control group. Changes in disease activity in the two groups during three consecutive IORRA phases were analyzed by adjusting for confounding factors.ResultsThe median 28-joint disease activity score (DAS28) decreased from 4.58 to 3.70 in the MTX + TAC group and from 4.12 to 3.61 in the control group. After adjusting for confounding factors, the decrease in the DAS28 score in the MTX + TAC group was significantly larger (by 0.273 points) than that in the control group (P < 0.05). ConclusionThis study demonstrated the efficacy of add-on therapy with TAC to MTX in patients with RA in daily practice.
Second language acquisition of American Sign Language influences co-speech gesture production

Abstract Previous work indicates that 1) adults with native sign language experience produce more manual co-speech gestures than monolingual non-signers, and 2) one year of ASL instruction increases gesture production in adults, but not enough to differentiate them from non-signers. To elucidate these effects, we asked early ASL–English bilinguals, fluent late second language (L2) signers (≥ 10 years of experience signing), and monolingual non-signers to retell a story depicted in cartoon clips to a monolingual partner. Early and L2 signers produced manual gestures at higher rates compared to non-signers, particularly iconic gestures, and used a greater variety of handshapes. These results indicate susceptibility of the co-speech gesture system to modification by extensive sign language experience, regardless of the age of acquisition. L2 signers produced more ASL signs and more handshape varieties than early signers, suggesting less separation between the ASL lexicon and the co-speech gesture system for L2 signers.
Objective and Subjective Assessment of Digital Pathology Image Quality

The quality of an image produced by the Whole Slide Imaging (WSI) scanners is of critical importance for using the image in clinical diagnosis. Therefore, it is very important to monitor and ensure the quality of images. Since subjective image quality assessments by pathologists are very time-consuming, expensive and difficult to reproduce, we propose a method for objective assessment based on clinically relevant and perceptual image parameters: sharpness, contrast, brightness, uniform illumination and color separation; derived from a survey of pathologists. We developed techniques to quantify the parameters based on content-dependent absolute pixel performance and to manipulate the parameters in a predefined range resulting in images with content-independent relative quality measures. The method does not require a prior reference model. A subjective assessment of the image quality is performed involving 69 pathologists and 372 images (including 12 optimal quality images and their distorted versions per parameter at 6 different levels). To address the inter-reader variability, a representative rating is determined as a one-tailed 95% confidence interval of the mean rating. The results of the subjective assessment support the validity of the proposed objective image quality assessment method to model the readers’ perception of image quality. The subjective assessment also provides thresholds for determining the acceptable level of objective quality per parameter. The images for both the subjective and objective quality assessment are based on the HercepTest TM slides scanned by the Philips Ultra Fast Scanners, developed at Philips Digital Pathology Solutions. However, the method is applicable also to other types of slides and scanners.
Physiological and ecological drivers of early spring blooms of a coastal phytoplankter

Drivers of phytoplankton blooms Despite decades of study, there is little evidence to link increases in phytoplankton growth in response to springtime warming with the dynamics of phytoplankton blooms. This lack of understanding makes it difficult to make predictions about global biogeochemical cycling in response to climate change. Hunter-Cevera et al. analyzed over a decade of data collected hourly from the New England shelf between 2003 and 2016 (see the Perspective by Worden and Wilken). Blooms now occur 20 days earlier than at the start of observations, because earlier springtime warming stimulates cell division earlier each year. Nevertheless, despite the shift in timing, predatory organisms in the food chain are still ready to consume the superabundance, which brings the blooms to an abrupt end each year. Science, this issue p. 326; see also p. 287 Warming-induced increases in replication drive earlier spring blooms in phytoplankton, but consumers remain in train. Climate affects the timing and magnitude of phytoplankton blooms that fuel marine food webs and influence global biogeochemical cycles. Changes in bloom timing have been detected in some cases, but the underlying mechanisms remain elusive, contributing to uncertainty in long-term predictions of climate change impacts. Here we describe a 13-year hourly time series from the New England shelf of data on the coastal phytoplankter Synechococcus, during which the timing of its spring bloom varied by 4 weeks. We show that multiyear trends are due to temperature-induced changes in cell division rate, with earlier blooms driven by warmer spring water temperatures. Synechococcus loss rates shift in tandem with division rates, suggesting a balance between growth and loss that has persisted despite phenological shifts and environmental change.
Implementation and evaluation of an adaptive routing protocol for infrastructureless mobile networks

Infrastructureless mobile networking relies on an ad hoc wireless network capable of forming and deforming communication routes on-the-fly. This paper describes the experience of implementing a distributed, adaptive and long-lived routing protocol called ABR (associativity-based routing) (C-K Toh, International Phoenix Conference on Computers & Communications (IPCCC'96), pp.480-486, 1996; C-K Toh, Journal on Wireless Personal Communications, vol.4, no.2, March 1997), which is based on the concept of associativity. Our implementation revealed that the modifications required to an existing TCP/UDP/IP/Ethernet protocol stack to support infrastructureless networking were minimal. We have also revealed that the experimental results (delay, throughput, and packet loss) obtained are satisfactory and the protocol can support many existing applications transparently.
Effect of Reminder Cards on Adherence to Treatment in Patients with Uncontrolled Hypertension

1 Associate Professor, Department of Nursing, Nursing and Midwifery Faculty, Urmia University of Medical Sciences, Urmia, Iran 2 MSc, Department of Nursing, Nursing and Midwifery Faculty, Urmia University of Medical Sciences, Urmia, Iran * Corresponding author: Masomeh Hemmati Maslakpak, Associate Professor, Department of Nursing, Nursing and Midwifery Faculty, Urmia University of Medical Sciences, Urmia, Iran. E-mail: Hemmati_m@umsu.ac. ir Received: 29 Aug 2015 Accepted: 17 Oct 2016
Perceived Transformational Leadership Behavior of Soccer Coaches and Its Relation to Players ’ Satisfaction at Arab Universities

This study aimed at investigating the perceived leadership behavior of university soccer coaches and its association with players’ satisfaction according to Bass’ (1985) transformational leadership theory. A total of 101 soccer players representing 16 Arab universities participated in this study. They completed a modified and translated version of the Multifactor Leadership Questionnaire developed by Bass and Avolio (1995) and Athlete Satisfaction Questionnaire developed by Riemer and Chelladurai (1998). Data were analyzed using descriptive statistics, Pearson product-moment correlation coefficients, and stepwise regression. The results of the study indicated that coaches were perceived by their players’ as utilizing moderate transformational leadership behavior. In addition, soccer players reported moderate levels of satisfaction. Moreover, the findings revealed a significant positive correlation between transformational leadership behavior and players’ satisfaction. The regression model indicated that transformational leadership factors, idealized influence, intellectual stimulation, and inspirational motivation were significant predictors of players’ satisfaction.
EFFECT OF SCANNING METHODS IN THE SELECTIVE LASER MELTING OF 316 L / TiC NANOCOMPOSITIES

Selective laser melting (SLM) is a promising additive manufacturing process that allows for the fabrication of complex functional components by the selective layer-by-layer melting of particles on a powder bed using a high-energy laser beam. In this study, the SLM process was used to fabricate components of TiC/ 316L stainless steel nanocomposite using various laser scanning methods. The results showed that the laser-scanning method used for the SLM process affects the degree of densification, microstructure, and the hardness of the components produced. We believe that the alternative fabrication route presented in this study should significantly increase the use of nanocomposites.
FAILURE PROBABILITY ASSESSMENT OF A PWR PRIMARY SYSTEM PIPING SUBCOMPONENTS UNDER DIFFERENT LOADING CONDITIONS

The integrity of the primary piping system of pressurized water reactors must be maintained during the plant lifetime. For the integrity analysis, credible structural analyses methodologies including fracture mechanics approach, etc., are required. Conventional deterministic approaches are being widely used for this purpose, but known to have many inherent uncertainties to encumber a coherent assessment. In this respect, probabilistic methodologies are considered as an alternative and appropriate technique for the structural integrity analysis of reactor piping system. In the nuclear reactor piping system, elbows were reported to be among the most highly stressed piping components. This requires an extensive flaw evaluation of these components. The objectives of this paper are to evaluate the fatigue failure probabilities of various subcomponents in a nuclear reactor primary system and to evaluate the relative risk ranking among them. For this purpose, a probabilistic fracture mechanics code using Monte Carlo simulation techniques was developed by incorporating both circumferential and longitudinal crack module. The developed code was used to calculate the fatigue failure probabilities due to small leak, big leak and LOCA situations subjected to all possible loadings. Finally, the effect of reduced inservice inspection interval on the failure probability was evaluated.
Acute administration of hexarelin stimulates GH secretion during day and night in normal men

OBJECTIVE Hexarelin is a synthetic hexapeptide with potent GH‐releasing activity in both animals and men. The aim of this study was to investigate the effect of a bolus injection of hexarelin given in the morning during wakefulness and during nocturnal sleep in a group of normal adult men.
Neuroprotective Effects of Nipradilol on Purified Cultured Retinal Ganglion Cells

PurposeTo investigate effects of nipradilol, a nonselective &bgr;- andbgr;-and selective &agr;1-receptor antagonist and a potential nitric oxide releaser, on retinal ganglion cells purified and cultured in a serum-free medium. MethodsRetinal ganglion cells were isolated from 2-day-old Sprague-Dawley rats by means of two-step panning. A series of nipradilol (10−5, 10−6, 10−7, 10−8, 10−9, and 10−10-mol/L) or vehicle solutions were administered to the culture medium for 48 hours, and the survival rate of retinal ganglion cells was evaluated using a newly developed system that evaluates the survival rate in small and large retinal ganglion cells separately. The effects of timolol maleate or bunazosin (10−5, 10−6, 10−7, and 10−8-mol/L) solutions on retinal ganglion cells survival were also evaluated. The survival rate was evaluated after 10−5-mol/L c-PTIO (2-[4-carboxyphenyl]-4,4,5,5 tetramethylimidazoline-1-oxyl-3-oxide potassium salt), a nitric oxide scavenger, was administered to retinal ganglion cells with 10−5-mol/L nipradilol. ResultsNipradilol significantly increased the survival rate of both small and large retinal ganglion cells in a concentration-dependent manner compared with the controls. The maximum survival rate improvement of small and large retinal ganglion cells was 29.1% and 14.5%, respectively. Although timolol maleate and bunazosin did not affect the survival rate, 10−5-mol/L c-PTIO significantly inhibited the nipradilol-induced survival rate improvement by 69.9% in small retinal ganglion cells and by 91.6% in large retinal ganglion cells. ConclusionNipradilol improves the survival rate of cultured postnatal rat retinal ganglion cells, and the nitric oxide generated from nipradilol may contribute to this effect.
Does BOT Project Perform Better ? A Comparison of Operation Performance foe BOT / Public / Private Recreational Areas

This study was to explore the differences and relationships of recreational satisfaction, cognition of operation performance, and cognition of BOT project in three recreational areas with private/public/BOT operation modes. A structural questionnaire including recreational satisfaction scale, cognition of operation performance scale and cognition of BOT project, was applied to collect data from visitors at Yamay Resort(BOT), Janfusun Fancyworld(Private) and Ali-shan forest recreation area(Public). The return questionnaires were filtered and coded into SPSS for further statistic analysis including, descriptive statistic, One-way ANOVA, Pearson Product-Moment Correlation Coefficient. The majority of samples was female, 21-30 years old, highly educated to academic level, lower monthly income under 20,000 NT dollars. The main findings were concluded as followings: 1. There was significant difference in different business model of recreational area of visitors’ recreation satisfaction, cognition of operation performance. 2. There was no significant difference in different business model of recreational area of visitors’ cognition of BOT project. 3. There was a positive correlation between recreational satisfaction and cognition of operation performance. 4. There was a positive correlation between recreational satisfaction and cognition of BOT project.