Miracle-dz/UniFAR-FTUs huggingface dataset:
Cultural transformations of love and sex in the digital age

This second volume of our journal addresses an uneasy topic. It is uneasy exactly because it is too easy to speak about love and sex and yet say nothing. It is uneasy because there has not been tremendous academic interest in this topic within the field of humanities and social sciences, and contributions to the field have thus been sporadic and unsystematic. Moreover, it is uneasy because, compared to other aspects of our everyday life, love and sex concern our being in a way that it is difficult to observe in a neutral or scientific way. However, we are here: organizing a small conference on the consequences for love and sex upon the advent of the internet and digital technologies. We could not resist engaging this topic because our program as a research center concerns the cultural changes of the digital age, and we can hardly think of another sphere of life more affected by the development of digital communications technologies.
Adaptively-Halting RNN for Tunable Early Classification of Time Series

Early time series classification is the task of predicting the class label of a time series before it is observed in its entirety. In time-sensitive domains where information is collected over time it is worth sacrificing some classification accuracy in favor of earlier predictions, ideally early enough for actions to be taken. However, since accuracy and earliness are contradictory objectives, a solution to this problem must find a task-dependent trade-off. There are two common state-of-the-art methods. The first involves an analyst selecting a timestep at which all predictions must be made. This does not capture earliness on a case-by-case basis, so if the selecting timestep is too early, all later signals are missed, and if a signal happens early, the classifier still waits to generate a prediction. The second method is the exhaustive search for signals, which encodes no timing information and is not scalable to high dimensions or long time series. We design the first early classification model called EARLIEST to tackle this multi-objective optimization problem, jointly learning (1) to decide at which time step to halt and generate predictions and (2) how to classify the time series. Each of these is learned based on the task and data features. We achieve an analystcontrolled balance between the goals of earliness and accuracy by pairing a recurrent neural network that learns to classify time series as a supervised learning task with a stochastic controller network that learns a halting-policy as a reinforcement learning task. The halting-policy dictates sequential decisions, one per timestep, of whether or not to halt the recurrent neural network and classify the time series early. This pairing of networks optimizes a global objective function that incorporates both earliness and accuracy. We validate our method via critical clinical prediction tasks in the MIMIC III database from the Beth Israel Deaconess Medical Center along with another publicly available time series classification dataset. We show that EARLIEST out-performs two state-of-the-art LSTM-based early classification methods. Additionally, we dig deeper into our model’s performance using a synthetic dataset which shows that EARLIEST learns to halt when it observes signals without having explicit access to signal locations. The contributions of this work are three-fold. First, our method is the first neural network-based solution to early classification of time series, bringing the recent successes of deep learning to this problem. Second, we present the first reinforcementlearning based solution to the unsupervised nature of early classification, learning the underlying distributions of signals without access to this information through trial and error. Third, we propose the first joint-optimization of earliness and accuracy, allowing learning of complex relationships between these contradictory goals.
Motivation Therapy in Children with Primary Monosymptomatic Nocturnal Enuresis

Meltem Erol, Unsal Ozkuvanci*, Ozgul Yigit, Dilara Fucucuoglu, Ozlem Bostan Gayret, Sezen Aksu** Bagcilar Training and Research Hospital, Clinic of Pediatrics, Istanbul, Turkey *Istanbul University Faculty of Medicine, Department of Pediatric Urology, Istanbul, Turkey **Bagcilar Training and Research Hospital, Clinic of Child Development Specialist, Istanbul, Turkey DOI: 10.4274/haseki.2795 Med Bull Haseki 2016;54:7-12
EVALUACIÓN DEL EXAMEN HEMATOLÓGICO EN EL DIAGNÓSTICO DE EHRLICHIOSIS CANINA EVALUATION OF THE HEMATOLOGY TEST IN THE DIAGNOSIS OF CANINE EHRLICHIOSIS

The present study evaluated the level of agreement between the hematology test and the direct ELISA assay for the diagnosis of canine ehrlichiosis. It was used 77 samples from dogs with clinical signs compatible with canine ehrlichiosis and 20 control samples from the Hospital of Small Animals of the Veterinary Medicine Faculty, San Marcos National University. The results showed 84.7 ± 11.0% of concordance by the Kappa test. Likewise, the thrombocytopenia, leukopenia, anemia and history of tick infestation were significantly related (p<0.05) to clinical evidence of the disease. The results revealed that the hematology test was important in the diagnosis of canine ehrlichiosis and that the direct ELISA was an excellent confirmatory test.
Mouthpiece Ventilation in Patients with Neuromuscular Disease: A Brief Clinical Review

The Open-circuit Mouthpiece Ventilation (MPV) is a mode of ventilation that uses a mouthpiece interface which the patient holds with the lips when he wants to be supported during inspiration. There exists a poor understanding of this method’s benefits compared to other modalities. Non-invasive ventilation (NIV) is sometimes reported as suboptimal in neuromuscular disease patients due to excessive secretions in the airways , hypercapnia due to inadequate ventilator settings , or because of a lack of tolerance of the interface. Interfaces that cover the nose and / or mouth and nose are the most commonly used, but may cause skin lesions and claustrophobia. Many of these drawbacks can be avoided by using a mouthpiece to administer the NIV. The MPV is used by many patients as daytime ventilatory support in combination with other modes of ventilation interface effective for night ventilation. There are two models mouthpiece of different sizes 15 and 22 mm . NIV has been used for years in patients with neuromuscular disorders as a viable alternative to continuous ventilatory support via tracheotomy tube. NIV is associated with a reduced risk of pneumonia and other respiratory complications. Its use in the volumetric mode allows air-stacking to improve cough. The mouthpiece interface facilitates speech and swallowing, factors that lead to a better quality of life for patients. This review aims to highlight the indications, along with the advantages and disadvantages of MPV.
Vasoespasmo cerebral posterior a hemorragia subaracnoidea aneurismática: Métodos diagnósticos y escalas de valoración

The cerebral vasospasm as a complication of subarachnoid hemorrhage (SAH), was described more than 50 years ago by Ecker and Riemenschnaider. The worldwide incidence of subarachnoid hemorrhage ranges from 6 to 10.5 per 100,000 people per year. The vasospasm is caused by the presence of blood in subarachnoid space. The neurological deficits caused by vasospasm, rarely appears within the first three days after SAH, becoming more frequent between days 6 8. The aneurysms can rupture at any time even during sleep, 85% of aneurysms rupture usually broken into the subarachnoid space, 15% into the brain parenchyma and ventricles. The peak of rebleeding is higher in the first 24 48 hours. The usefulness of Transcranial Doppler value is forecast in cerebral vasospasm. The cerebral angiography remains the gold standard for diagnosis of vasospasm. The use of calcium antagonists is still used for prevention of cerebral vasospasm.
Nove mogućnosti tretmana akne u adolescenciji New Treatment Possibilities in Adolescent Acne

Sažetak Acne vulgaris jedna je od najcescih dermatoza uopce. Lijecenje je u velike vecine bolesnika vrlo uspjesno, a ovisi o obliku akne. Kod blažih slucajeva primjenjuje se samo lokalna terapija, a kod srednje teskih i teskih slucajeva uz lokalnu se istodobno daje i opca terapija. Redovitim ciscenjem kože i lokalnom, danas najcesce kombiniranom, keratolitickom i antimikrobnom terapijom nastoji se s kože ukloniti pretjerani lipidni sloj, sprijeciti zacepljenje otvora folikula i stvaranje novih komedona te papula i pustula. Kod srednje teskih oblika bolesti uz lokalne terapijske mjere uobicajeno se daju antibiotici, najcesce tetraciklini u nižim dozama ili azitromicin, dok je kod najtežih oblika bolesti i dalje terapija izbora peroralno primijenjen izotretinoin.
Síntomas psicológicos y conductuales como factores de progresión a demencia tipo Alzheimer en el deterioro cognitivo leve

Introduction. Mild cognitive impairment (MCI) is a cognitive disturbance in which intensity is not enough to be classified as dementia and does not affect significantly the functioning or activities of daily living. The MCI has a progression rate to Alzheimer-type dementia (ATD) related to different factors. Aim. To evaluate the association between the presence of psychological and behavioural symptoms (PBS) with progression to ATD en MCI subjects. Patients and methods. We evaluated 318 patients with MCI assessed in a Dementia Unit of Catalonia between 1998 to 2002 who were followed five years afterthe MCI diagnosis. We determined the PBS presence, those classified as affective, behavioural and psychotic symptoms. We also assessed sociodemographic aspects and the ApoE genotype. Results. The mean age was 74 ± 7.87 years-old, 56.7% presented PBS, with affective (53%), behavioural (32.2%) and psychotic symptoms (14.8%). In the study, 32.1% progressed to ATD. We found association between the presence of PBS and the progression to ATD (OR = 2.77; 95% CI = 1.66-4.63), specifically with behavioural and psychotic symptoms. The ApoE epsilon4 allele showed association with the progression to ATD (OR =1.81; 95% CI =1.11-2.94). The logistic regression model showed a significant association between the PBS and the epsilon4 allele with the progression to ATD. Conclusions. The PBS presence in MCI patients is associated with ATD progression with or without ApoE epsilon4 allele.
Pipeline to Success

The purpose of this research was to examine the impact of an educational pipeline on two subsets of students. The first subset entered the school pipeline in the sixth grade and was continuously enrolled through the 12th grade. The second subset of students entered the school’s pipeline in the ninth grade and was continuously enrolled through the 12th grade. This study measured and compared the resiliency, academic achievement, and attendance of a total of 68 students who attended a public secondary school in a large urban city in the Northeast Region of the United States. An educational pipeline provides the necessary structures whereby a student can get the support he or she needs because the student traveled within the confines of one system as opposed to attending separate middle and high schools. The pipeline can provide the necessary resources that help cultivate student success and a supportive school environment. The results of this quantitative study showed no significant difference between students who entered the pipeline in the sixth grade and those who entered in the ninth grade across all three variables: resiliency, academic achievement, and attendance. Document Type Dissertation Degree Name Doctor of Education (EdD) Department Executive Leadership First Supervisor Sandye P. Johnson Second Supervisor LaTasha Hamlett-Carver This dissertation is available at Fisher Digital Publications: https://fisherpub.sjfc. edu/education_etd/363
Manifestaciones disautonómicas en sujetos presintomáticos y enfermos de ataxia espinocerebelosa tipo 2

Background: Patients with type 2 spinocerebellar ataxias (E-SCA2) frequently complaint about symptoms of the autonomous nervous system (ANS). Nowadays, it is not clear if these patients present abnormalities in the regulation of the ANS during the presymptomatic stage of the disease (PS-SCA2). Objective: To determine the presence of autonomic dysfunction in E-SCA2 and PS-SCA2. We hypothesized that the rate of autonomic symptoms in carriers of the SCA2-gene mutation is higher than in healthy control subjects. Patients and methods: Ninety seven E-SCA2 and forty eight PS-SCA2 genetically diagnosed patients were assessed using the standardized clinical autonomic Scale for Outcomes in Parkinson’s disease (SCOPA-AUT). The markers were compared with healthy subjects, similar in age and sex. Results: The patients and PS-SCA2 showed an increase in the rate and severity of the disautonomic symptoms than those of the control group, predominating symptoms related to the urinary (39.7%) and gastrointestinal (30.6%) system; where constipation (19.3%) and pollakiunia (17.7%) were frequent in PS-SCA2 and pollakiunia (19%),
Super‐Clothoids

Piecewise clothoids are 2D curves with continuous, piecewise linear curvature. Due to their smoothness properties, they have been extensively used in road design and robot path planning, as well as for the compact representation of hand‐drawn curves. In this paper we present the Super‐Clothoid model, a new mechanical model that for the first time allows for the computing of the dynamics of an elastic, inextensible piecewise clothoid. We first show that the kinematics of this model can be computed analytically depending on the Fresnel integrals, and precisely evaluated when required. Secondly, the discrete dynamics, naturally emerging from the Lagrange equations of motion, can be robustly and efficiently computed by performing and storing formal computations as far as possible, recoursing to numerical evaluation only when assembling the linear system to be solved at each time step. As a result, simulations turn out to be both interactive and stable, even for large displacements of the rod. Finally, we demonstrate the versatility of our model by handling various boundary conditions for the rod as well as complex external constraints such as frictional contact, and show that our model is perfectly adapted to inverse statics. Compared to lower‐order models, the super‐clothoid appears as a more natural and aesthetic primitive for bridging the gap between 2D geometric design and physics‐based deformation.
Attitudes of Physician Assistants to Hospice Care and Assisted Suicide

&NA; As primary health care providers, physician assistants (PAs) often treat patients with terminal illnesses. Surveys of physicians and nurse practitioners have shown hospice to be underutilized as a referral option, and requests for assisted suicide to be commonplace. A randomly selected group of PAs licensed in Illinois responded to a questionnaire concerning their attitudes toward hospice and assisted suicide. The survey examined demographic information about the PAs and their personal views, experience, and education with respect to assisted suicide and hospice care. The respondents reported that the main deterrents to hospice care were Medicare/insurance guidelines and lack of personal knowledge about hospice. The central reasons identified for opposition to the legalization of assisted suicide were fear of its abuse and religious/moral deterrents.
Comparison of Supreme LMA, Proseal LMA and Cobra PLA in adult patients undergoing minor surgery

Endotrekeal entübasyon, 1981 yılına kadar cerrahi girişimlerde hava yolu açıklığının güvenli bir şekilde sağlanmasının tek yolu olarak görülmekteydi. Fakat Brain tarafından üretilen ilk supraglotik hava yolu aracı olan, klasik laringeal maske (LMA) bu durumu değiştirmiştir (1). Laringeal maske kullanımı yıllar içerinde hızla yaygınlaşmış ve anestezi uygulamasında birçok avantaj sağlamıştır (2, 3).
Antiulcerogenic activities of Agelanthus dodoneifolius leaf against acetyl salicylate and ethanol induced ulceration in rats

Antiulcer and antioxidant activities of crude methanol (800 and 1600 mg/kg bw), n-hexane and ethyl acetate fractions (800 mg/kg bw) of Agelanthus dodoneifolius were investigated against acetylsalicylate and ethanol induced ulcer in rats. The methanol fraction had the highest ulcer protective effect (73.33 ± 7.40%), better than the cimetidine (60.00±8.54 %) while the ethyl acetate fraction had the least (26.66 ± 6.66 %) in ethanol model, however, in acetyl salicylate model, crude extract exhibited the highest (54.16 ± 4.16 %) and the lowest (33.33 ± 4.16 %) protective effect at 1600 and 800 mg/kgbw respectively. The methanol faction preserved the integrity of the epithelial mucosal better than the other fractions. Treatment with crude and fractions of A. dodenofolius significantly (p
non b non c related hepatocellular carcinoma with sarcomatous change due to epithelial mesenchymal transition

We describe a case of non-B Non-C related hepatocellular carcinoma and sarcomatous change in a 91-year-old woman who had not undergone previous anticancer treatment. Ultrasonography revealed a 40 × 60 mm hyperechoic nodule in segment 4; contrast enhanced ultrasound and contrast enhanced computed tomography revealed hypervascularity in the early phase and defect in the Kupffer phase; super Paramagnetic Iron Oxide magnetic resonance imaging revealed defect on T2-weighted images; US-guided liver biopsy revealed mixed components of moderatelyto poorly-differentiated hepatocellular carcinoma and pleomorphicand spindle-cell type sarcoma. The background of the liver was almost normal and without liver cirrhosis. Immunohistochemical findings of the hepatocellular carcinoma component were as follows: positive for CAM5.2, AE1/ AE3, CK20, AFP, Hepatocyte-paraffin-1 antibody and S-100p, and negative for CK7, vimentin (VMT), CK19, CD34, and αSMA. The sarcomatous component was positive for CAM5.2, AE1/AE3, S-100p, VMT, and negative for CK7, CK20, CD34, AFP, αSMA and hepatocyte-paraffin-1 antibody. The Ki-67 index was less than 5% in both hepatocellular carcinoma and sarcomatous components. Moreover, in terms of EMT, the hepatocellular carcinoma component was positive for E-cadherin, and the sarcomatous component was positive for Snail and HES-1 in the nucleus, and negative for E-cadherin and P-ERK. The above findings led to our diagnosis of the case as one of hepatocellular carcinoma with sarcomatous change attributed to EMT. Further study is needed to clarify the histogenesis of sarcomatous hepatocellular carcinoma not administered previous treatment for hepatocellular carcinoma.
Spinning Out of Control? How Academic Spinoff Formation Overlooks Medical Device Regulations

This paper investigates the impact of the medical device regulatory framework on the academic spinoﬀ formation process and contributes to knowledge in the domain by expanding and deepening our understanding of its underlying routines and capabilities. A detailed case study focusing on academic spinoff formation in the Irish medical device industry was conducted and found that the consideration given to the medical device regulatory framework significantly lags behind that given to other commercialisation activities. This trend has potential to both significantly delay spinoff formation and negatively impact its potential success and survival. Findings indicate that incorporating expert regulatory knowledge earlier within the process may enhance the spinoff activities within universities, particularly funding, research and capital investment.
The clinical utility of neutrophil to lymphocyte ratio in pregnancy related complications: a mini-review

Pregnancy-related complications (PRCs) are potent contributors to mortality and morbidity in pregnant women. Prediction and early recognition of PRCs are crucial to improve its prognosis. The pathogenesis of PRCs is complex and it is well-recognized that inflammation response is involved in several types of PRCs. Therefore, inflammatory markers are usually used as predictors or prognostic factors in PRCs. Neutrophil to lymphocyte ratio (NLR), which is calculated from complete blood count and dedifferentiation, is a simple and easily obtainable inflammatory index. Accumulated studies have shown that NLR is an indicator of PRCs. In this minireview, we summarized the evidence regarding the clinical utility of NLR in PRCs, including preeclampsia, gestational diabetes mellitus, hyperemesis gravidarum, preterm delivery and ectopic pregnancy.
Database Aware Memory Reconstruction for Object Oriented Programming Paradigm

— Data storage is a big challenge in front of industries and researchers when its growing enormously. Traditional data storage strategy was fulfilling the business needs till the data was in structured format. But now due to Internet of Things (IoT) compatible devices unstructured data is more than structured one. In such cases traditional data storage strategy won't work efficiently. Initially data storage devices used to store the data irrespective of its logical storage. It means the record was stored either in array format or block format. Such type of storage was not matching physical and logical structure. Logically, structured data is generated as an attribute of particular entity, but physically it gets stored in a sequential memory storage either as file or as memory block. Object Based Storage pattern(OBS) stores the data in the way object gets generated by the programmer and accordingly memory is allocated for that object. Object contains all the data related to that particular entity which makes it easy to retrieve it back. Current study includes comparative advantages, operations and study of different service providers of object-based storage. We also focused on the current need of object-based storage structure for big data analysis and cloud computing.
UNIVERSIDAD SAN FRANCISCO DE QUITO USFQ Colegio de Posgrados Perpendicular STT-MTJs with Double Reference Layers and its Application to Downscaled Memory Cells

Chip design presents problems due to scaling as the technology node reaches to the physical limits. The roadmap to 7nm technology node and beyond is already traced and overcome the problems in power and energy dissipation have become a fundamental part in the chip design. Memories on chip design take place a fundamental role and it became a crucial component, which defines the performance of the system. To encompass the problems a lot of research in MRAM has been done, leading to significant positive results focused on nonvolatile memories with less power in operations. These devices are called Magnetic Tunnel Junction (MTJ) where different designs are proposed in order to accomplish the new technology node demands. This thesis presents the analysis of an array of 128×128 STT-MRAM by using two type of devices, the Single Barrier (SB) MTJ and the Double Barrier (DB) MTJ. The fundamentals of the MTJ current flow and important phenomena such as the Tunnel MagnetoResistance (TMR) and the Perpendicular Magnetic Anisotropy (PMA) will be explained. The objective is to study the behavior of an STT-MRAM where it is shown the advantages, disadvantages, and trade-off between SB and DB performances. For each type of device, a set of four type of configurations is taken, and through a deterministic and statistical analysis, the optimal configuration in terms of energy will be chosen. Besides, the bitcell structure is a combination of the FinFET and MTJ technology and in consequence, a hybrid model is used. In the hybrid design, the general approach for circuit design changes. In this thesis, we combine two different models, the MOS model provided by the foundry and the MTJ model represented in a Verilog-A code due to the absence of commercial models.