Miracle-dz/UniFAR-FTUs huggingface dataset:
Tracking Data Trajectories in IoT

The Internet of Things (IoT) devices access and process large amounts of data. Some of them are sensitive and can become a target for security attacks. As a consequence, it is crucial being able to trace data and to identify their paths. We start from the specification language IOT-LYSA, and propose a Control Flow Analysis for statically predicting possible trajectories of data communicated in an IoT system and, consequently, for checking whether sensitive data can pass through possibly dangerous nodes. Paths are also interesting from an architectural point of view for deciding which are the points where data are collected, processed, communicated and stored and which are the suitable security mechanisms for guaranteeing a reliable transport from the raw data collected by the sensors to the aggregation nodes and to servers that decide actuations.
Revision of Surgical Management of Malignant Obstructive Jaundice at Al-Bashir Teaching Hospital in Amman – Jordan

ackground: Malignant Obstructive Jaundice (MOJ) is caused by different diseases at different levels and stages. Ideally, the best management is by early diagnosis and treatment with multi-disciplinary approach that includes the full cooperation among endoscopists, histopathologists, interventional radiologists, oncologists and surgeons. Objective: This analytic retrospective study puts a light on the management of MOJ patients at the surgical department of Al-Bashir Teaching Hospital in Amman – Jordan. The gradual changes in the surgical management were taken in consideration. Method: The study included 98 patients who were treated surgically for MOJ during the period from June 1999 to June 2006. The age of these patients ranged from 27 years to 85 years, with the mean age being 62 years. The data obtained includes the investigations done, type, stage and level of MOJ, the type of surgical procedure and the postoperative complications within 1 month. Results: Most of the patients were males, 58 patients with a percentage of (59.18%). The remaining 40 patients were females with a percentage of (40.82%). The types of surgical management included Wipple's procedure for 16 patients with a percentage of (16.33%), tumor resection for 3 patients with a percentage of (3.06%), bypass (palliative) procedures for 69 patients with a percentage of (70.41%) and the remaining 10 patients with a percentage of (10.20%) were found to be inoperable during diagnostic laparotomy. In general, the surgical management had a morbidity of (18.37% 18 patients) of which the mortality was (14.28% 14 patients of these 18 morbid patients). Regarding investigation, U/S was performed for 62 patients only. It was positive in 30 patients with a percentage of (48.39%). Endoscopic Retrograde Cholangiopancreatography (ERCP) was done in 34 patients, it was positive in 18 patients with a percentage of (52.94%). Abdominal CT scan was performed for 44 patients, it was positive in 38 patients with a percentage of (86.36%). MRCP was done in 14 patients, it was positive in 12 patients with a percentage of (85.71%). Conclusion: MOJ is a disease occurring more frequently in middle age and elderly groups. Most of the patients are presented lately, making the most common surgical procedure performed for these patients being palliative (bypass) procedure. The use of sophisticated investigations is shown to aid in the diagnosis and staging of MOJ.
Narrow branch preservation in morphological reconstruction

We present a morphological approach to the reconstruction of fine branching structures in three dimensional data, developed from the basic procedures of reconstruction by dilation. We address a number of closely related questions arising from this reconstruction goal, including issues of structuring element size and shape, noise propagation, iterated approaches, and the relationship between geodesic and conditional dilation. We investigate and assess the effect and importance of these considerations in the context of the overall reconstruction process, and examine the effectiveness of the approach in addressing the task of reconstructing narrow branch features in noisy data.
In vitro multiplication of pear tree cultivar Cascatense

One main obstacle to the development and expansion of pear tree cultivation in Brazil has been the lack of cultivars adapted to the edaphoclimatic conditions of regions with the potential for pear production. Intending to overcome this hindrance, Embrapa Clima Temperado (Embrapa Temperate Climate) developed and released the cultivar Cascatense, with a low cold requirement (~400 h) better suited for Rio Grande do Sul`s and Santa Catarina`s climate. Still, seedlings of high genetic and sanitary quality are necessary for the establishment of a high-yield orchard. Plants with both sanitary quality and uniformity can be obtained through in vitro micropropagation. Thus, the present study aimed to assess the influence of different culture media (MS, MS¾, WPM, QL, and Himedia), concentrations of sucrose (0, 15, 30, 45, and 60 g L-1), and concentrations of benzylaminopurine (BAP) (0, 0.4, 0.8, 1.2, and 1.6 mg L-1) upon the in vitro multiplication of cultivar Cascatense, to establish an efficient protocol to enhance its propagation and reproducibility. The study included three sequential experiments in which the number of shoots per explant, the length of shoots, the number of axillary buds per shoot, fresh mass, and dry mass of shoots were evaluated. Cultivar Cascatense can be best propagated in vitro with the use of Himedia medium, supplemented with 0.8 mg L-1 of BAP and 30 g L-1 of sucrose.
Application of DG-DGGE to analyze microbial community diversity and population dynamics in fermentative hydrogen-producing system

Anaerobic microflora enriched from sewage sludge produces hydrogen by using molasses wastewater as its substrate. Use has been made of the double gradient-denaturing gradient gel electrophoresis (DG-DGGE) to monitor the genetic diversity and dynamics of microbial communities in a bio-hydrogen producing reactor. Samples of the anaerobic sludge were analyzed every 7 days, and genomic DNA of the microbial community was extracted. After purification of the DNA by using the DNA gel recovery kit, the 16S rRNA genes (V2 to V3 region) were amplified by using the universal primers (F63GC and R518). The results of agarose gel (2%) electrophoresis show that the PCR products are about 450bp in length. These amplified DNA fragments were separated by parallel DGGE with the denaturant (urea and formamide) from 30% to 60%. The profile of DGGE changes when sludge is inoculated in the reactor, both the primary community dies out or increases, and a second micriobial community increases quickly. The change of the community structure is the greatest on the 15th day. As community succession increases with time, the community structure declines in complexity and a stable community structure forms. On the 29th day, the community diversity stops changing and the amount of the microbial dominant populations reach 19 OTUs. The community diversity tends to be stable after the decreasing under the competition and the cooperation of bacteria, and a climax community forms. Some kinds of populations have been existing in the community structure, they are primary communities. There are some great differences in composition and quantity of the dominant population between the primary community and the climax community. The primary community and the second community have a cooperation effect in the metabolizing process; show the complex ecological characteristics of the microbial community. This is because different niche conditions lead to different enrichment of bacteria, and forms different microbial community structures. Only by enriching and selecting the needed dominant populations fast can produce hydrogen effectively in the reactor.
Assessment of DNA damage in females with type 2 diabetes mellitus

Diabetes mellitus ist eine der am haufigsten vorkommenden chronischen Erkrankungen mit einer kontinuierlich steigenden Pravalenz und Inzidenz. Weltweit leiden 387 Millionen Menschen an DM, wovon T2DM mit 90-95 % den Grosteil der Erkrankungen ausmacht. DM ist gekennzeichnet durch einen Anstieg des Blutzuckers, der sogenannten chronischen Hyperglykamie. Die metabolischen Faktoren fuhren zu DNA-Schaden. Hyperglykamie und die damit verbundenen Risikofaktoren wie Bluthochdruck und Fettstoffwechselstorung fuhren zu einer direkt toxischen Wirkung von Zucker auf das Gewebe und somit zu Veranderungen kleiner und groser Gefase, den mikro- und makrovaskularen Komplikationen. Viele Studien zeigen Hinweise auf ein erhohtes Sterblichkeitsrisiko bei Diabetikern die an Krebs leiden. Diese Evidenz wurde bei verschiedenen Krebserkrankungen gezeigt. Oxidativer Stress gilt als wichtigster Mediator bei der Entstehung von DNA-Schaden bei Diabetikern. Die Akkumulation dieser DNA-Schaden kann zu Mutationen fuhren. Somit sind DNA-Schaden eine mogliche biologische Verbindung zwischen DM und Krebs. In dieser Masterarbeit, welche im Rahmen der Querschnittstudie "MIKRODIAB" durchgefuhrt wurde, wurden die Auswirkungen von T2DM auf DNA-Schaden mittels comet assay untersucht. 146 weibliche Typ 2 Diabetikerinnen wurden innerhalb ihrer routinemasigen Untersuchungen, in der Diabetesambulanz im Gesundheitszentrum Wien-Sud, rekrutiert. DNA Strangbruche (Lyse) und oxidative DNA-Schaden (FPG) wurden in isolierten Lymphozyten (PBMC'S) und in Vollblut evaluiert. Weiters wurden auch H₂O₂ induzierte DNA-Schaden in PBMC'S untersucht. Um die Haupthypothese zu prufen wurden die Probandinnen nach ihrer glykamischen Kontrolle in zwei Gruppen geteilt. 74 Probandinnen gehorten der gut kontrollierten Gruppe (HbA1c ≤ 7.5 %) an und 72 Probandinnen gehorten der schlechte kontrollierten Gruppe (HbA1c > 7.5) an. DNA-Schaden wurden mittels Comet Assay evaluiert. Fur die zweite Hypothese wurden die Probandinnen in Tertilen geteilt, welche nach Diabetesdauer eingeteilt waren (Mittelwerte: 6.94 ± 3.09 Jahre, 13.35 ± 1.14 Jahre, 22.96 ± 7.35 Jahre). Es wurden keine signifikanten Ergebnisse in DNA-Schaden und gut kontrollierten Typ 2 Diabetikerinnen versus schlecht kontrollierter Typ 2 Diabetikerinnern erhalten. Weiters wurden auch keine Verbindungen zwischen DNA-Schaden und der Diabetesdauer evaluiert. Daher mussen die Haupthypothese und auch die zweite Hypothese verworfen werden. Abschliesend ist zu sagen, dass keine Unterschiede in DNA-Schaden unter Berucksichtigung von HbA1c oder der Diabetesdauer bei Typ 2 Diabetikerinnen in Osterreich evaluiert werden konnte. Wir schliesen daraus, die Studienpopulation zu homogen war um signifikante Unterschiede in DNA-Schaden mit dem Comet Assay zu erhalten.
Cepas de Candida albicans en pacientes con diabetes mellitus

Un pequeno numero de hongos son capaces de causar enfermedades en el hombre. Es de gran importancia, conocer y priorizar la investigacion sobre la resistencia farmacologica a las que se estan presentando en la infeccion oportunista, es el caso de la Candida albicans, son en pacientes que se encuentran inmunodeprimidos por enfermedades degenerativas como es la diabetes. Los diabeticos por la cantidad de azucar en la sangre no mantienen el equilibrio simbiotico con esta clase de hongo, tornandose oportunista al aprovechar la debilidad corporal y al incurrir en una reproduccion exponencial de sus colonias infectivas, danando principalmente las mucosas y los tejidos del individuo. Se ha realizado una seleccion de textos y explicaciones concernientes no solo a describir y definir la enfermedad de la diabetes sino a comprender perfectamente el comportamiento del hongo segun los estudios disponibles para conocer de que manera se limita la fitoterapia conocida para el tratamiento cuando se trata de pacientes diagnosticados diabeticos. La infecciones oportunistas por Candida albicans en pacientes diabeticos estan ocasionando una tasa alta de incidencia en las infecciones candidiasica y por la cultura ecuatoriana a la automedicacion estamos promoviendo. Entre las zonas corporales, a las cuales se ven expuesto, los pacientes diabeticos a sufrir de una infeccion por candidiasis, va a estar mediada por el buen control de la diabetes mellitus. Siendo esta una enfermedad de fondo, un factor intrinseco degenerativo, que no solo debilita al sistema inmune, si no que deshidrata y quebranta la piel, cambia el ph corporal, produce desnutricion por la mala asimilacion de los nutrientes, produce estados inflamatorios en los organos, obstaculiza la formacion y el transito de las celulas inmunocompetentes, lo que permite a la Candida spp, como parte de la microflora, se transformarse en oportunista y causar una infeccion en el organismo.
A Prospective Multicenter Evaluation of the Accuracy and Safety of an Implanted Continuous Glucose Sensor: The PRECISION Study

Abstract Background: A prior study (PRECISE II) demonstrated that an implantable continuous glucose monitoring (CGM) system (Eversense® CGM System) provided accurate glucose readings through the 90-day sensor life with a favorable safety profile in participants with type 1 or type 2 diabetes (T1D, T2D). This study was performed to further characterize the accuracy of the system. Methods: PRECISION was a prospective multicenter study that evaluated the accuracy and safety of Eversense among adults with T1D or T2D through 90 days (NCT02647905). Accuracy measures included percentage system agreement and mean absolute relative difference (MARD) between Eversense and Yellow Springs Instrument reference measurements from 40 to 400 mg/dL. The primary safety endpoint was incidence of device-related or sensor insertion/removal procedure-related serious adverse events (SAEs) through 90 days. An updated glucose calculation algorithm was also applied to the sensor data from the PRECISE II study to evaluate consistency of accuracy results. Results: Thirty-five participants received the CGM system. Eighty-five percent of CGM values were within 15/15% of reference and the MARD value against reference was 9.6% (95% confidence interval [CI]: 8.9–10.4). All sensors were functional through day 90. No device- or procedure-related SAEs occurred. Application of the updated algorithm to PRECISE II sensor data resulted in 87% of readings within 15/15% of reference and an MARD value against reference of 8.5% (95% CI: 8.0%–9.1%). Conclusions: PRECISION corroborated prior accuracy and safety findings of the Eversense CGM System through the 90-day sensor life. The updated algorithm improved accuracy of measurements in PRECISE II.
Crop Pollen Development under Drought: From the Phenotype to the Mechanism

Drought stress induced pollen sterility is a harmful factor that reduces crop yield worldwide. During the reproductive process, the meiotic stage and the mitotic stage in anthers are both highly vulnerable to water deficiency. Drought at these stages causes pollen sterility by affecting the nature and structure of the anthers, including the degeneration of some meiocytes, disorientated microspores, an expanded middle layer and abnormal vacuolizated tapeta. The homeostasis of the internal environment is imbalanced in drought-treated anthers, involving the decreases of gibberellic acid (GA) and auxin, and the increases of abscisic acid (ABA), jasmonic acid (JA) and reactive oxygen species (ROS). Changes in carbohydrate availability, metabolism and distribution may be involved in the effects of drought stress at the reproductive stages. Here, we summarize the molecular regulatory mechanism of crop pollen development under drought stresses. The meiosis-related genes, sugar transporter genes, GA and ABA pathway genes and ROS-related genes may be altered in their expression in anthers to repair the drought-induced injures. It could also be that some drought-responsive genes, mainly expressed in the anther, regulate the expression of anther-related genes to improve both drought tolerance and anther development. A deepened understanding of the molecular regulatory mechanism of pollen development under stress will be beneficial for breeding drought-tolerant crops with high and stable yield under drought conditions.
Spatial Regions Periodicity based Detection of Two-wheelers using Histogram of Oriented Gradients

Recent research has been devoted and focused on detecting pedestrians and vehicles in intelligent vehicles except for vulnerable road users (VRUs). Histogram of Oriented Gradients (HOGs) descriptor is one of the state-of-art methods which have been shown to significantly outperform the existing feature set for several objects detection. In this paper we present a method for two-wheelers detection based on the periodicity of the size of spatial regions; cells and blocks. Contrary to concatenating feature vectors using a dense grid of HOG, proposed algorithm storage extracted feature vectors according to the period in each step. Experimental results show that the new approach gives higher detection accuracy than that of the conventional method.
Clock Synchronization in IoTs Network through Cloud

The Internet of Things is a trending future technological revolution that emerging distributed computing and real-time based application and its development depends on dynamic technical innovation in a number of important fields from wireless sensors to nanotechnology. Cloud integration with IoT made things more convenient and easy. Clock synchronization between a system in a distributed network is the complex and tedious job. It is mandatory to get sync with other and source as well. There are many proposed ways of data synchronization protocols like NTP, GPS (Global Position System) to maintain sync process between Systems or IoT devices network. In this paper, we are proposing a clock synchronization approach to sync clocks between IoTs and Cloud which are connected with each other in distributed network. Here we have used cloud service SaaS (Software as a Service) to collect the information to analysis and trigger the results action to IoTs. In this paper, we present the Clock Synchronization based on Precision time protocol(PTP) between IoTs Simulation model for Omnet++ with INET framework, which allows us to check clock sync accuracy with a different network configured topologies. We have tried to minimize the clock drift with clock offset updating and with master-slave phenomena also minimize the master-slave delay. To show our simulation results we have used chunks nodes of IoTs in distributed manner placed in different places with different clock values. The simulation result shows that proposed approach works in the desired manner within ideal and network delay symmetry.
Life-Threatening Angioedema Following Varenicline Administration.

CASE REPORT RK is a 7-year-old schoolboy diagnosedwith ADHD with a predominantly hyperactive/ impulsive presentation. The clinical diagnosis was made by the child and adolescent psychiatrist according to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, supported by the Vanderbilt ADHD Diagnostic Scale parent and teacher versions. Immediate-release MPH was commenced at 5 mg in the morning, and RK developed acute nasal bleeding 3 to 4 hours after the first dose. The bleeding stopped without interventionwithin an hour, and this recurred after the second dose on the next day. RKwas taken to the emergency department, and his physical examination including blood pressure was normal. The otorhinolaryngologist's nasal examination and the coagulation profile were found to be normal. The IR-MPH was withheld for a week where no bleeding was noted. Because the investigations were normal, the medication was recommenced after 7 days, and a similar bleeding manifestation followed. These bleeding manifestations were seen during the autumn, and there was no use of a humidifier in the living environment. Eight years back RK's older brother MK was diagnosed with ADHD and was commenced on IR-MPH when he was 8 years old. He developed nasal bleeding lasting less than an hour after 3 to 4 hours after his first and second doses. This was seen during the spring. Similar to RK, MK's physical examination and coagulation profile were normal at that time. There is no family history of nosebleeds, hematological disorders, and bleeding after the use of medications. Their father and his brother had features suggestive of ADHD during their childhood but had not been formally diagnosed. Both brothers were commenced on dexamfetamine after omitting IR-MPH and are clinically stable on lisdexamfetamine without any bleeding manifestations. Both of them had normal cognitive profiles, no other psychiatric comorbidities, and no nasal trauma and were not on any other medications. Specific platelet function tests such as for platelet aggregation were not done because the bleeding stopped after IR-MPH was omitted in both of them. The Naranjo probability scale is a questionnaire used for determining the likelihood of whether an adverse drug reaction is actually owing to the pharmacological agent rather than the result of other factors. Application of this instrument to the nasal bleeding manifestations of RK and
Hyperspectral Image Classification Based on Novel Binary Particle Swarm with Mutation Mechanism for Band Selection

Hyperspectral remote sensing sensors can capture hundreds of narrow contiguous bands and provide plenty of valuable information. Duo to the high-dimension characteristics of hyperspectral data, band selection plays an important role in the field of Hyperspectral Image (HSI) classification. In this paper, a HSI classification method based on Novel Binary Particle Swarm Optimization with mutation mechanism (MNBPSO) for band selection is proposed. First, we present a thorough experimental study to show the superiority of the MNBPSO method. Then we introduce a pre-processing method for feature selection and parameters determination simultaneously based on MNBPSO. Experiments are conducted on the Indian Pines dataset. The evaluation results show that the proposed approach can select those bands with more discriminative information and improve the classification accuracy effectively. Keywords—binary particle swarm optimization; band selection; parameters determination; mutation mechanism; support vector machines
Guiding Consumers through Lemons and Peaches : A Dynamic Model of Search over Multiple Characteristics

The increasing amount of data available to consumers has most likely aided in decision-making. However, it has also created an opportunity for sellers to design the information landscape that consumers navigate. This paper develops a novel fully dynamic search model for alternatives with multiple characteristics, and reports estimation results for an online used car seller. The model allows characterizing search over alternatives with multiple characteristics that may be distributed arbitrarily. It also allows for a rich set of consumer search behaviors, including piecemeal search within and arbitrary paths across alternatives. We estimate the model using clickstream data on the website of a used car seller. The dataset tracks incremental search actions as well as test-drive reservations. The estimated fundamentals are then used to consider the effects of different information design policies. We find that the choice of the characteristics to be made available to consumers upfront may have conversion implications ranging from -0.39% to +1.65%. While the (theoretical) perfect information scenario increases conversion rates by 10.4%, we find that there is not a clear monotonic relationship between consumer search intensity and firm performance. Finally, we compare our model with the knowledge gradient model of learning (a myopic model used in the Operations literature), and show that taking forward-looking behavior into account explains the moments of the data better, and that the models’ likelihoods are significantly different. ∗Graduate School of Business, Stanford University, Stanford, California 94305. We thank Carlos Daniel Santos, Ilya Morozov, and Robert Sanders for helpful comments as well as the participants of research seminars at Catolica Lisbon, INSEAD, Nova School of Business and Economics, Stanford W.I. P., and UC San Diego. Correspondence: Gardete: gardete@stanford.edu, Antill: mkhunter@stanford.edu.