Miracle-dz/UniFAR-FTUs huggingface dataset:
DCMI Abstract Model

This document specifies an abstract model for DCMI metadata [DCMI]. The primary purpose of this document is to provide a reference model against which particular DC encoding guidelines can be compared. To function well, a reference model needs to be independent of any particular encoding syntax. Such a reference model allows us to gain a better understanding of the kinds of descriptions that we are trying to encode and facilitates the development of better mappings and translations between different syntaxes. This document is primarily aimed at the developers of software applications that support Dublin Core metadata, people involved in developing new syntax encoding guidelines for Dublin Core metadata and those people developing metadata application profiles based on the Dublin Core.
Red cell transfusion : a practical guide

From Donor to Patient Sandra J. Nance. Overview of Immunology Nancy M. Heddle. Compatibility Testing For Red Blood Cell Components: Approaches and Limitations Kathleen Sazama. Transfusion in the Face of Autoantibodies Steven R. Sloan and Leslie E. Silberstein. Red Blood Cell Transfusion of the Immunocompromised Patient Christopher P. Stowell. Red Blood Cell Transfusions for Selected Neonatal and Pediatric Patients Elaine K. Jeter and Mary Ann Spivey. Transfusion Support in Solid-Organ Transplantation Darrell J. Triulzi. Hematopoietic Stem Cell Processing and Transplantation Patricia L. Kotula Ellen M. Areman and Ronald A. Sacher. Massive Transfusion Richard K. Spence. Autogeneic and Directed Blood Transfusions Pearl T. C. Y. Toy. Triggers for the Transfusion of Red Cells William C. Sherwood. Chronic Transfusion Support Karen E. King and Paul M. Ness. Modern Approaches To The Diagnosis and Management of Red Cell Transfusion Reactions Patricia M. Kopko and Dennis Goldfinger. Clinical and Laboratory Impact of Blood Group Antigens and Antibodies Beat M. Frey and Marion E. Reid. Index.
Régulation du cycle cellulaire des cellules exposées aux radiations ionisantes

Comment les dommages de l’ADN sont-ils transduits en signaux intracellulaires qui controlent la regulation du cycle cellulaire ? Il a ete montre recemment que la proteine ATM (ataxia telangectasia mutated) et/ou le complexe proteique DNA-PK (DNA-dependent protein kinase), deux proteines kinases activees par les dommages de l’ADN, pourraient induire un arret de la progression cellulaire en activant la proteine suppresseur de tumeur p53. La p53 activee agit comme facteur de transcription et regule l’expression de nombreux composants impliques dans les voies de regulation du cycle cellulaire. Le plus connu, la proteine p21WAF1/CIP1, est un inhibiteur des CDK, une famille de proteines kinases connues comme regulateurs cles de la progression du cycle cellulaire. p21WAF1/CIP1 est capable d’inhiber de nombreuses CDK, mais est plus efficace envers les cyclines de G1/S. D’autres inhibiteurs de CDK, p27KIP1 et p15INK4b, sont induits par les radiations ionisantes et contribuent a l’arret en G1. Il a egalement ete montre que l’arret en G2 radio-induit necessitait une phosphorylation inhibitrice de la kinase cdc2, via une voie de signalisation ATM-dependante. Les regulateurs du cycle cellulaire sont des cibles privilegiees des processus oncologiques et peuvent etre responsables d’une reponse defaillante des cellules tumorales aux radiations ionisantes. La fonction principale de l’arret en G1 passant par p53 permet l’elimination des cellules ayant des lesions de l’ADN alors que l’arret en G2 jouerait au contraire un role essentiel dans la survie des cellules irradiees. Les mecanismes de surveillance du cycle cellulaire, et plus particulierement de l’arret en G2, offrent un nouvel eventail de cibles potentielles et il se developpe une pharmacologie de G1 et G2 visant a potentialiser l’effet des radiations ionisantes. La suppression de l’arret en G2 par les methylxantines comme la cafeine ou les inhibiteurs des proteines kinases comme la staurosporine et UCN-01 (7-hydroxystaurosporine) sensibilise les cellules aux radiations ionisantes. Ces donnees n’ont pas conduit a des applications cliniques mais confirment que viser a supprimer l’arret en G2 peut etre une strategie importante pour la therapie des cancers.
Contribuição do uso de medicamentos para a admissão hospitalar

According to the Word Health Organization, adverse drug reactions (ADR) are any harmful and non intentional answer which occurred in doses normally used in human beings. The ADR can be responsible for 2.4% to 11.5% of hospital admissions. Therefore, this study aimed at knowing the admitted patient´s demographic profile due to possible ADR, identifying the most frequent drugs and complaints, and evaluating the incidence of hospital admission related to drug use. Patients who were 18 years old or more and were admitted during a period of one month to a medical clinical of a general hospital were interviewed for one month about drug use before being admitted, as well as regarding to the complaint which led them to hospital. These information were analyzed according to official data, like MICROMEDEX® and WHO criteria as well. It was observed that the admission due to drug use occurred in most part of the cases in elderly [47.5% (66/139)] and women [62% (87/139)]. The most frequent drugs used were: omeprazole (16), analgesics (31), antihypertensive (31), simvastatin (7) and formoterol fumarate (6), and the symptoms were normally associated to the digestive (20.5%), circulatory (20.2%), respiratory (18.2%) and central nervous systems (13.9%). It was estimated that 15.5% (139/897) of the hospital admission occurred possibly due to the drug use. The data found by present study suggests some strategies in order to prevent ADR in the context of primary health care services, such as monitoring drug therapy, manly for patients with chronic diseases, elderly and polimedicated people; and pharmaceutical care including dispensation and purchasing of the drugs, a lot of them dispensed over the counter (OTC).
PERCEPCIÓN DE LA SALUD Y ACTIVIDADES REALIZADAS EN EL TIEMPO LIBRE POR ADOLESCENTES QUE VIVEN EN MEDIOS RURALES

This work he examines the property of lifestyle in the perception of health. I object the population of study he is composed of 1109 students of 10 to 16 years that they enjoy in two Spanish communities’s half way rural. In the study we have utilized like instrument of work the questionnaire Self Administered Physical Activity Checklist (SAPAC) adapted to the Spanish population. We utilized descriptive fellow’s analysis, to the analysis inferencial and the test of contrast Chi cuadrado (x2). Aftermath demonstrated the existence of differences in the perception of health in terms of the sex (p=.000), of age (p=.000) and of the dwelling place (p=.015). Of equal form the television consumption (p =.029), the time dedicated to the computer (p =.034), the time dedicated to the school tasks (p =.034) and the accomplishment of physical activity (p =.000) they relate to the perception of the health. Lifestyle relates with the perception that the teens have of his health.
Development of the Rotterdam Renal Replacement Knowledge- Test (R3K-T)

Introduction: There is currently a lack of validated or standardized measures to test the level of knowledge among renal patients regarding kidney disease and available treatment options. We conducted a pilot study to develop a questionnaire measuring knowledge of kidney disease, dialysis and transplantation options. The main aim of this study was to develop such an instrument for further use in research and practice. Method: An initial 61 item pool was generating by searching the literature and consulting experts in this area for additional items. This questionnaire was completed by 182 renal disease patients from 4 dialysis centers in the Rotterdam municipality. A factor analysis was conducted using the maximum likelihood factor method followed by direct oblimin rotation to obtain variance explained by each factor. Questions that loaded ≥ . 30 on a factor were included. Results: Twenty-seven patients (24%) were in the pre-RRT phase, 60 (54%) were undergoing haemodialysis, 16 (14%) were undergoing peritoneal dialysis, and 9 (8%) had a graft failure. Forty (36%) were female and 72 (64%) were male. Age range 19-87 (median = 59). A factor analysis was conducted to reduce the number of items. This resulted in 30 items consisting of 5 subscales regarding knowledge on: kidney disease (5 items, α = .37), peritoneal dialysis (4 items, α = .73), haemodialysis (4 items, α = .41), kidney transplantation (12 items, α = .86), quality of life (5 items, α = .59). Discussion: This study aimed to develop an instrument with which knowledge of kidney disease and the related treatment options can be reliably measured. This study resulted in a short and easy to administer knowledge questionnaire. We intend to further explore the psychometric properties of this instrument and develop norm scores for the general public and patients at various stages of the disease and treatment. We have also considered translated versions of this questionnaire.
Analytical computation of spatial traffic distribution in a typical region of a cellular network by proposing a general mobility model

We propose a general mobility model based on region splitting and mapping each subregion on a multi-server node. By using the theory of multi-class Jackson queueing network with multiserver nodes and employing the product-form solution for such queueing networks, we obtain an analytical form for the spatial traffic distribution in a typical region with specific number of users. To this end, we consider the spatial statistical pattern for new and handoff call arrivals and the ratio between these two types of arrivals. At last, we apply our new model to some simple mobility scenarios and compute the resultant active user's location densities.
How the Phoneme Inventory Changes its Shape: A Cognitive Approach to Phonological Evolution and Change

In this paper I propose an interpretation of a series of phonological changes in the history of English (including Old English Breaking and the early Modern English Great Vowel Shift) from a cognitive phonology perspective. My analysis is based on Nathan (1886, 1995, 1996), who applies prototype theory to phonological description. In Nathan's analysis, the louder a sound is, the more prototypical effects it possesses. In processes of phonological change, phonemes change their number of prototypical effects. According to this view, we propose a classification that is based on two different prototypicality effects: degree of height and degree of peripherality. By treating both sound and meaning unit as mental categories, I try to show how the principles of categorization and generalization motivate similar diachronic patterns both in the phonological and in the semantic domain.
Combination of adoptive cell transfer, anti-PD-L1 and anti-LAG-3 antibodies for the treatment of recurrent tumors

Tumor recurrence may result from the exhaustion of tumor-associated antigen (TAA)-specific T cells, which often occurs upon chronic antigen stimulation. We have recently shown that the blockade of the T-cell inhibitory receptors PD-L1 and LAG-3 restores TAA-specific CD4+ T-cell functions in mice bearing recurrent neoplasms, resulting in robust antineoplastic effects.
A 3D approach for object recognition in illuminated scenes with adaptive correlation filters

In this paper we solve the problem of pose recognition of a 3D object in non-uniformly illuminated and noisy scenes. The recognition system employs a bank of space-variant correlation filters constructed with an adaptive approach based on local statistical parameters of the input scene. The position and orientation of the target are estimated with the help of the filter bank. For an observed input frame, the algorithm computes the correlation process between the observed image and the bank of filters using a combination of data and task parallelism by taking advantage of a graphics processing unit (GPU) architecture. The pose of the target is estimated by finding the template that better matches the current view of target within the scene. The performance of the proposed system is evaluated in terms of recognition accuracy, location and orientation errors, and computational performance.
The diagnosis, prevalence and prognosis of delirium in an older hospital population

Delirium is a syndrome which is characterised by a change in cognition, attentional difficulties and alterations to the sleep-wake cycle. In most cases it is caused by the onset of a physical illness. Delirium is more commonly found in older people aged 65 years or older, with prevalence in hospital being as high as 42%. Delirium is associated with negative outcomes such as increased length of hospital admissions, institutionalisation and mortality. There are tools which can identify and measure delirium and its associated symptoms. The Delirium Rating Scale-Revised-98 is claimed to be a valid tool, but its use in older patients in general hospital has not been fully investigated and there is limited research to support its validity in such a population. A cohort study of older people with mental health problems admitted to general hospital was used to establish whether the DRS–R–98 was able to distinguish delirium from other mental health problems, to examine the association between DRS-R-98 scores, demographic variables and health problems and to study outcomes associated with delirium. 250 patients over 70 years admitted to hospital as an emergency and likely to have a mental health problem on the basis of screening were recruited and 249 completed a battery of questionnaires including the DRS-R-98 at baseline. 180 days later 121 participants completed a follow-up questionnaire. 128 participants were lost to follow-up due to refusal of the outcomes questionnaire, ill-health, withdrawal, mortality or being un-contactable after the baseline questionnaire. Delirium was common in the study population (43%). The odds of having delirium increased with the presence of dementia (odds ratio=6.7) and functional disability (odds ratio=4.5). It was not significantly associated with mortality or length of stay in hospital. It was associated with recoverable cognitive impairment. The DRS-R-98 has reasonable content, concurrent and predictive validity but compared with clinician diagnosis the sensitivity and specificity of the DRS-R-98 were modest (about 0.75). The validity of the DRS-R-98 was not as strongly supported as in other research, which reported sensitivity and specificity as high as 0.98 and 0.77 respectively. This could be due to the differences in participant populations, as the participants of this study were all older patients with mental health problems on general hospital wards. In view of its ability to discriminate groups the DRS-R-98 is sufficiently valid for use in epidemiological research, but its moderate sensitivity and specificity make it unsuitable for use alone in clinical practice on individual patients, especially in populations where co-morbid dementia is prevalent.
ACCIDENTES Y COMPLICACIONES EN ANESTESIA DE PEQUEÑOS ANIMALES (I)

General anaesthesia is produced by a controlled depression of the CNS which it is associated with a doserelated cardiorespiratory depression. Therefore, general anaesthesia is always associated to a vital risk, even in the healthy patient. There are few studies in Veterinary Medicine determining the percentages of morbi-mortality associated to general anaesthesia. However, it has been observed that common anaesthetic accidents and complications occur during the recovery from anaesthesia. The correct preoperative assessment of the patient and the continuos monitorization of the anaesthetized patient until fully recovery has been accomplished, allow an early diagnosis and treatment of the most common anaesthetic complications. These accidents and complications occurring commonly in small animal anaesthesia are reviewed in the present paper.
Grid systems in graphic design : a visual communication manual for graphic designers, typographers and three dimensional designers = Raster Systeme für die visuelle Gestaltung : ein Handbuch für Grafiker, Typografen und Ausstellungsgestalter

This book is suitable for those who work with automated text and image design. It shows examples of working correctly on a conceptual level. Exact directions for using all of the grid systems presented (8 to 32 grid fields) are given to the user. These can be used for the most varied of projects. The three-dimensional grid is treated as well. Put simply: a guidebook from the profession for the profession. The development of organisational systems in visual communication was the service and the accomplishment of the representatives of simple and functional typography and graphic design. In the 1920s in Europe, works already arose in the areas of typography, graphic design and photography with objectified conception and rigid composition. In 1961 a brief presentation of the grid with text and illustrations appeared for the first time in an earlier book by the author. Articles published mainly in trade journals then followed. This book now attempts to close a gap by giving examples and exact directions to the professional concerning all grid problems that can occur. The author, a world-renowned professional, thus offers his colleagues the tools to solve problems more easily.
Master-slave quadruped walking robot

The real time recognition of the environment and the decision of the control signal to each actuator are very important for control of a walking robot on rough terrain. Techniques are not perfect at present. So, we propose master-slave quadruped walking robots using radio control devices, which can use efficiently the recognition and control function of a human. In the paper, we describe experiments for walking using a prototype of a master-slave quadruped walking robot. This robot can walk forward and backward on even terrain, and can get over low steps. The experimental results show the validity of the proposed master-slave quadruped walking robot.
Pediatric critical care medicine : basic science and clinical evidence

Section I The Practice of Pediatric Critical Care Medicine. - Section II The Science of Pediatric Critical Care Medicine. - Section III Resuscitation and Stabilization of the Critically Ill Child. - Section IV The Respiratory Tract in Critical Illness and Injury. - Section V The Cardiovascular System in Critical Illness and Injury. - SectionVI The Central Nervous System in Critical Illness and Injury. - Section VII The Gastrointestinal Tract in Critical Illness and Injury. - SectionVI The Endocrine System in Critical Illness and Injury. - Section IX Fluids and Electrolytes in Critical Illness and Injury. - Section X Hematologic/Oncologic Problems in Critical Illness and Injury. - Section XI The Immune System in Critical Illness and Injury. - Section XII Trauma. - Section XIII Pharmacology and Toxicology in the PICU. - Section XIV Environmental Emergencies.
Aprendizaje discriminativo de clasificadores Bayesianos

El aprendizaje de modelos de clasificacion Bayesianos es, generalmente, un proceso generativo. Es decir, en el aprendizaje de dichos modelos se busca maximizar la verosimilitud del conjunto de datos dado el modelo aprendido. Sin embargo, existe otra aproximacion, el aprendizaje discriminativo, en la que se busca maximizar la verosimilitud condicional. Esta parece, en principio, una aproximacion mas natural para propositos de clasificacion. No obstante, no siempre los modelos aprendidos mediante un metodo discriminativo son mejores que los aprendidos con metodos generativos. Recientemente han aparecido en la bibliografia varios metodos para el aprendizaje discriminativo de clasificadores Bayesianos. En el presente articulo, se presenta un nuevo metodo para el aprendizaje discriminativo, tanto de la estructura como de los parametros, de clasificares Bayesianos. Esta aproximacion esta basada en la adaptacion del algoritmo TM a modelos de clasificacion Bayesianos. Por otra parte, en el presente articulo, tambien se presenta una evaluacion experimental del metodo propuesto aplicado a diferentes bases de datos estandares para clasificacion supervisada.
Developing, implementing and evaluating diabetes care training for nurses and nursing aides in nursing homes and municipal home‐based services

AbstractThe increasing prevalence of diabetes among older people challenges nurses and nursing aides in providing high-quality evidence-based care in nursing homes and municipal home-based services. Deficiencies in treatment and follow-up care, as well as significant need for educating personnel, are emphasised. Organisational challenges related to transferring tasks from specialist to primary health care services imply an urgent need for enhanced professional competence.We aim to describe the development, implementation and evaluation of an educational training programme for nurses and nursing aides in nursing homes and municipal home-based services.Sixteen registered nurses and four nursing aides participated (women, aged 32–59 years). Three main principles were emphasised in the development of the programme: enhancing professional authority; improving communication within professions and levels of care; and reflections based on experience with patients and perceived challenges in clinical practice. To .
El tratamiento del niño y adolescente con TDAH en Atención Primaria desde el punto de vista de la evidencia

Paediatricians in Primary Care are the first professionals who assess the child with a possible attention deficit hyperactivity disorder (ADHD). Once the diagnosis is established, their responsibility is to initiate and/or follow-up an optimal treatment, with demonstrated efficacy by the scientific community, individualized to each case in order to minimize risks; cost-effective and taking into account the opinion of informed patients.
‘Skills for employability? No need thanks, we’re radiographers!’Helping graduate healthcare professionals to stand out from the crowd

Graduate healthcare professionals are facing increasing competition for jobs and where the baseline qualification is common to all applicants, the need to ‘stand out from the crowd’ becomes of particular significance. The dilemma for higher education institutions (HEI) that provide education for the healthcare professions (hcp) is that the skills and attributes for those professions are specific and identified within regulatory and professional standards. These standards mould the curriculum requirements for hcp education whereas generic skills for employability are largely left to HEIs to interpret and embed within a curriculum that is already full in ensuring that professional competencies are achieved. Within this study, radiography and radiotherapy managers from a range of healthcare providers were asked to define and rank their top 5 employability skills and to identify how they would test for these in job applicants. Alongside this, the expectations and perceptions of employability of a cohort of final year undergraduate radiography students at one university were explored and it was found that while students acknowledged the need for employability skills, they considered these to be integrated into their degree programme. Following on from this, students were invited to attend and evaluate a series of employability skills development sessions. Findings further suggested that student radiographers are ill equipped to recognise the skills and attributes for employability valued by employers as a discriminator of applicants for band 5 radiographer jobs. The value of the skills development opportunities offered to this cohort was acknowledged but they recommended that sessions are offered earlier in the course.