Miracle-dz/UniFAR-FTUs huggingface dataset:
Autonomic Reactivity and Personality

In 28 male and 42 female college students, rs between scores for Psychoticism, Neuroticism, Extraversion, and Lying from the Eysenck Personality Inventory and a measure of sympathetic dominance were of low magnitude, failing to support Eysenck's hypothesis that neuroticism is associated with imbalance in the autonomic nervous system.
Multi- and Unisensory Visual Flash Illusions

The role of stimulus structure in multisensory and unisensory interactions was examined. When a flash (17 ms) was accompanied by multiple tones (each 7 ms, SOA < 100 ms) multiple flashes were reported, and this effect has been suggested to reflect the role of stimulus continuity in multisensory interactions. In experiments 1 and 2 we examined if stimulus continuity would affect concurrently presented stimuli. When a relatively longer flash (317 ms) was accompanied by multiple tones (each 7 ms), observers reported perceiving multiple flashes. In experiment 3 we tested whether a flash presented near fixation would induce an illusory flash further in the periphery. One flash (17 ms) presented 5° below fixation was reported as multiple flashes if presented with two flashes (each 17 ms, SOA = 100 ms) 2° above fixation. The extent to which these data support a phenomenological continuity principle and whether this principle applies to unisensory perception is discussed.
A new order splitting model with stochastic lead times for deterioration items

In unreliable supply environments, the strategy of pooling lead time risks by splitting replenishment orders among multiple suppliers simultaneously is an attractive sourcing policy that has captured the attention of academic researchers and corporate managers alike. While various assumptions are considered in the models developed, researchers tend to overlook an important inventory category in order splitting models: deteriorating items. In this paper, we study an order splitting policy for a retailer that sells a deteriorating product. The inventory system is modelled as a continuous review system (s, Q) under stochastic lead time. Demand rate per unit time is assumed to be constant over an infinite planning horizon and shortages are backordered completely. We develop two inventory models. In the first model, it is assumed that all the requirements are supplied by only one source, whereas in the second, two suppliers are available. We use sensitivity analysis to determine the situations in which each sourcing policy is the most economic. We then study a real case from the European pharmaceutical industry to demonstrate the applicability and effectiveness of the proposed models. Finally, more promising directions are suggested for future research.
The GPR55 ligand L‐α‐lysophosphatidylinositol promotes RhoA‐dependent Ca2+ signaling and NFAT activation

The endogenous phospholipid l‐α‐lyso‐phosphatidylinositol (LPI) was recently identified as a novel ligand for the orphan G protein‐coupled receptor 55 (GPR55). In this study we define the downstream signaling pathways activated by LPI in a human embryonic kidney (HEK) 293 cell line engineered to stably express recombinant human GPR55. We find that treatment with LPI induces marked GPR55 internalization and stimulates a sustained, oscillatory Ca2+ release pathway, which is dependent on Gα13 and requires RhoA activation. We then establish that this signaling cascade leads to the efficient activation of NFAT (nu‐clear factor of activated T cells) family transcription factors and their nuclear translocation. Analysis of cannabinoid ligand activity at GPR55 revealed no clear effect of the endocannabinoids anandamide and 2‐arachidonoylglycerol;however, the classical CB1 antagonist AM251 evoked GPR55‐mediated Ca2+ signaling. Thus, LPI is a potent and efficacious ligand at GPR55, which is likely to be a key plasma membrane mediator of LPI‐mediated signaling events and changes in gene expression. —Henstridge, C. M. , Balenga, N. A. B. , Ford, L. A. , Ross, R. A. , Waldhoer, M. , Irving, A. J. The GPR55 ligand l‐α‐lysophosphatidylinositol promotes RhoA‐dependent Ca2+ signaling and NFAT activation. FASEB J. 23, 183‐193 (2009)
Intraoperative Push–Prone Test: A Useful Technique to Determine the Lowest Instrumented Vertebra in Adolescent Idiopathic Scoliosis

Study Design: A retrospective review of 24 cases of adolescent idiopathic scoliosis (AIS). Intraoperative push–prone test to determine the lowest instrumented vertebrae (LIV). Objective: To determine the LIV using intraoperative push–prone test. Background: Determination of the LIV in surgical treatment of the AIS remains controversial. Different classifications schemes have been proposed to help surgeons in making this decision. Most schemes depend on flexibility views. However, variability in technique of obtaining flexibility views and interpretation of these views in relation to the classification schemes make decision making in choosing the LIV difficult. Methods: An intraoperative push–prone image was used to determine LIV. Results: We were able to stop 1 or 2 levels above the stable vertebra in most cases. All patients had a well-balanced thorax over the pelvis. Conclusions: Intraoperative push–prone test is a useful adjunct to predict the LIV in AIS.
Prostate cancer prevention

Purpose of review Prostate cancer, a common cause of morbidity and mortality in the developed world, ought to be a preventable disease. This review focuses on prostate cancer prevention in the context of new mechanistic insights into human prostatic carcinogenesis. Recent findings Evidence is accumulating to implicate infection and inflammation as contributors to prostate cancer development. Inherited prostate cancer susceptibility genes discovered thus far encode participants in host responses to infection. Proliferative inflammatory atrophy, a prostate cancer precursor lesion, ties inflammatory responses to prostatic carcinogenesis. Somatic epigenetic alterations, present in all prostate cancers, appear to arise in the setting of inflammation. Finally, a newly identified somatic genome change, involving a fusion between an androgen-regulated gene, TMPRSS2, and genes encoding members of the ETS family of transcription factors, may provide a clue as to why prostate cancer cells exhibit androgen dependence for growth and survival. Summary The contributions of infection and inflammation to the early development of prostate cancer suggest prevention strategies featuring prevention or eradication of infection, amelioration of inflammation, or attenuation of genome-damaging reactive oxygen and nitrogen species. The acquisition of androgen dependence later during prostate cancer pathogenesis suggests the use of approaches targeting androgen signaling, including inhibitors of 5α-reductase.
Generating secret in a network

This monograph studies the theory of information through the multiuser secret key agreement problem. A general notion of mutual dependence is established for the secrecy capacity, as a natural generalization of Shannon's mutual information to the multivariate case. Under linear-type source models, this capacity can be achieved practically by linear network codes. In addition to being an unusual application of the network coding solution to a secrecy problem, it gives secrecy capacity an interpretation of network information flow and partition connectivity, further confirming the intuitive meaning of secrecy capacity as mutual dependence. New identities in submodular function optimization and matroid theory are discovered in proving these results. A framework is also developed to view matroids as graphs, allowing certain theory on graphs to generalize to matroids. In order to study cooperation schemes in a network, a general channel model with multiple inputs is formulated. Single-letter secrecy capacity upper bounds are derived using the Shearer-type lemma. Lower bounds are obtained with a new cooperation scheme called the mixed source emulation. In the same way that mixed strategies may surpass pure strategies in zero-sum games, mixed source emulation outperforms the conventional pure source emulation approach in terms of the achievable key rate. Necessary and sufficient conditions are derived for tightness of these secrecy bounds, which shows that secrecy capacity can be characterized for a larger class of channels than the broadcast-type channels considered in previous work. The mixed source emulation scheme is also shown to be unnecessary for some channels while insufficient for others. The possibility of a better cooperative scheme becomes apparent, but a general scheme remains to be found. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.)
Wafer-level chip scale MEMS oscillator for wireless applications

This invited paper presents the first chip-scale packaged MEMS oscillator solution that meets the stringent requirements for cellular applications. The temperature compensated MEMS oscillator (TCMO™) meets the frequency stability requirement of ±2.5 ppm from -30°C to +85°C, phase noise of -130 dBc/Hz at 1 kHz for a 13 MHz carrier, start-up time of below 2.5 ms and current consumption of less than 5 mA. With dimensions of 1.44×1.04×0.55 mm3 the MEMS oscillator requires less than half the volume of the smallest 2016 TCXO. Importantly, due to the hermetic chip-scale package it can be integrated with larger ICs and SAW/BAW components into larger overmolded modules.
Epitope Driven Broad Spectrum Peptide Vaccines against MDR Pathogens

Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumonia have evolved as a group of co-existing multidrug resistant nosocomial pathogens spreading worldwide. Overuse of antibiotics has led to the emergence of pan drug resistant bacterial strains and has made all antimicrobial agents superfluous including carbapenems and even the last resort antibiotic-colistin, resulting in high mortality rates among the hospitalized patients. Vaccination is highly effective and successfully used strategy that reduces the incidence of infectious diseases, yet efforts towards development of vaccines for nosocomial infections are scant. In this direction, a broad spectrum vaccine is the futuristic need providing protection not only against A. baumannii but against the whole group of co-existing nosocomial pathogens.
Inclusão digital na terceira idade: avaliação de usabilidade em sites de cadastro de correio eletrônico

Este trabalho apresenta duas etapas: primeiramente, analisa as respostas dadas por 25 sujeitos com idades entre 40 e 79 anos sobre a necessidade e os beneficios relacionados a aprendizagem das tecnologias em geral e do computador e da internet em particular; a segunda etapa analisa, em decorrencia dos resultados obtidos na primeira, por meio da avaliacao de usabilidade, as dificuldades encontradas por tres pessoas idosas em tres sites de cadastro de correio eletronico comumente utilizados - Gmail, Yahoo! Brasil, e iBest - e aponta acoes corretivas e perspectivas para o desenvolvimento de paginas de criacao de correio eletronico que sigam diretrizes de usabilidade para pessoas na terceira idade.
Testosterone increases thromboxane A2 receptor density and responsiveness in rat aortas and platelets.

Testosterone has been implicated as a risk factor for cardiovascular diseases. Thromboxane (Tx) A2 is an important pathophysiological mediator for thrombotic vascular diseases. This study investigated the effects of testosterone on platelet and vascular TxA2 receptors. Male rats were treated with either testosterone cypionate for 2 wk, sham operated, castrated, or castrated and treated with testosterone cypionate for 2 wk. Treatment of intact rats with testosterone significantly (P < 0.001) increased the TxA2 receptor density in platelets from 25.4 +/- 3.2 to 42.9 +/- 4.2 fmol/mg protein (P < 0.005, n = 17) and in aortic membranes from 48.7 +/- 1.7 to 86.1 +/- 6.1 fmol/mg protein, n = 9. The threshold concentration of the TxA2 mimetic, [1S-(1 alpha, 2 beta(5Z),3 alpha(1E,3R*)4 alpha)]-7-[3-(3-hydroxy-4- (4'-iodophenoxy)-1-butenyl)-7-oxabicyclo[2.21]heptan-2-yl]-5 -heptenoic acid (I-BOP), to induce platelet aggregation was significantly (P < 0.01) decreased from 0.45 +/- 0.16 nM, n = 7, in the control rats to 0.07 +/- 0.01 nM, n = 13, in the testosterone-treated rats. Testosterone treatment resulted in a significantly (P < 0.05) greater maximum aortic contractile response to the TxA2 mimetic, U-46619, compared with intact rats. Castration resulted in a significant (P < 0.01) decrease in aortic TxA2 receptor density from 51.7 +/- 3.7 to 27.3 +/- 5.3 fmol/mg protein, which was significantly reversed by testosterone treatment (89.2 +/- 7.1 fmol/mg protein; n = 4). Castration resulted in a significantly (P < 0.05) lower maximal aortic contractile response that was reversed by treatment with testosterone. Castration did not significantly change platelet TxA2 receptor density. (ABSTRACT TRUNCATED AT 250 WORDS)
QoS based handover in heterogeneous networks

Today, the user is interested in comparing one service with another in terms of universal, user-oriented performance parameters which apply to any end-to-end service. The QoS concept encapsulates the idea that different data streams could be treated differently by the network depending upon the service being carried. QoS features shall provide the required performance of latency, jitter and packet loss needed to support the service. In this paper we have analyzed QoS in case of Wi-Fi/WiMAX and WiMAX / Wi-Fi handover.
Light at Night and Cancer Risk¶

Abstract Environmental lighting powerfully suppresses the physiologic release of melatonin, which typically peaks in the middle of the night. This decreased melatonin production has been hypothesized to increase the risk of cancer. Evidence from experimental studies supports a link between melatonin and tumor growth. There is also fairly consistent indirect evidence from observational studies for an association between melatonin suppression, using night work as a surrogate, and breast cancer risk.
The SK3/KCa2.3 potassium channel is a new cellular target for edelfosine

BACKGROUND AND PURPOSE The 1‐O‐octadecyl‐2‐O‐methyl‐sn‐glycero‐3‐phosphocholine (edelfosine) is an ether‐linked phospholipid with promising anti‐cancer properties but some side effects that preclude its full clinical therapeutic exploitation. We hypothesized that this lipid could interact with plasma membrane ion channels and modulate their function.
Autonomic neuropathy and inappropriate secretion of antidiuretic hormone. Occurrence in a patient with bronchogenic carcinoma.

WHILE the syndrome of inappropriate secretion of antidiuretic hormone is a well-recognized complication of bronchogenic carcinoma, 1 its combination with autonomic dysfunction seems much less common. 2,3 There appears to be only one previous report describing a patient in whom loss of sweating, hypotension, and nonobstructive urinary retention were noticed. 4 Another report describes this combination with a pancreatic carcinoma. 5 A patient with the combined effects of autonomic neuropathy and hyponatremia had metastatic bronchogenic carcinoma. Report of a Case A 65-year-old man had a one-year history of severe constipation, 6-kg weight loss, impotence, and two episodes of collapse in which he had lost consciousness. Examination, sigmoidoscopy, barium enema examination, and chest roentgenograms were normal, but the serum sodium level was 120 mEq/L. One month later he was admitted as an emergency with attacks of feeling distant in which he could not speak and other episodes in which he lost
Técnica de Tenzel en la cirugía reconstructiva de los tumores malignos palpebrales

RESUMEN: Se realizo un estudio descriptivo de tipo restrospectivo en el periodo comprendido entre marzo de 1995 y diciembre del 2000, tomando como universo a 24 pacientes operados de tumor maligno de los parpados, a los cuales fue necesario realizar cirugia reconstructiva, utilizando para ello el injerto rotado de Tenzel. El 91,8 % de los pacientes fueron operados por carcinoma basocelular. El 70,8 % de los casos se encontraban en el estadio T2 y el 29,2 % en el estadio T3. Los resultados cosmeticos fueron buenos en 22 pacientes para el 91,8 %. Las complicaciones, todas posoperatorias, incluyeron el ectropion marginal en 2 casos, uno de los cuales presento ademas, persistencia tumoral, la dehiscencia de sutura solo se observo en 1 paciente. La recuperacion quirurgica fue de 10 dias en 4 pacientes (16,7 %), de 15 dias en 16 (66,7 %), de 20 dias en 3 (12,5 %) y solo 1 caso tardo 30 dias para recuperarse. Fue posible realizar esta tecnica en el 40 % de los pacientes operados por tumores malignos palpebrales. El resultado cosmetico alcanzado con esta tecnica es bueno y la recuperacion quirurgica fue posible en 15 dias en mas de la mitad de los pacientes.
The kinematics of contact with compliance

The kinematics of contact describes the motion of a point of contact over the surfaces of two contacting objects in response to a relative motion of these objects. In a previous work (Int. of Robotics Res., vol.3, p.17-32, 1988), the author derived equations that embody this relationship when the two objects are assumed to be rigid bodies. In the present work, he extends that analysis by dropping the assumption of rigidity. He derives a set of equations, called the compliant contact equations, which model the kinematics of contact with compliance. He discusses an example that illustrates the effect of compliance on the kinematics of contact. He measures the trajectory of the center of contact on a tactile sensor in response to a known motion and shows how the results fit the proposed model. He analyzes how two tasks that are based on the rigid-body model of the kinematics of contact have been designed to be robust with respect to compliance. For the task of contour-following he provides experimental results that confirm this analysis. <<ETX>>
Characterization of temperate bacteriophages of Bacillus thuringiensis.

Summary Eight phages lysogenic for Bacillus thuringiensis var. galleriae which elicit the lytic response in B. thuringiensis var. subtoxicus were isolated by induction of the host strains. We have divided these phages into three groups: group I, phages GT-1 to GT-5; group II, GT-6 and GT-7; group III, GT-8. The following properties of the phages were examined: morphology, host range, serum neutralization, adsorption rates, one-step growth characteristics and thermal inactivation rates. The three groups are readily distinguishable on the basis of morphology and host range. Group II and III show a high degree of homology in regard to their host range, serum neutralization, one-step growth and thermal inactivation characteristics. The phages bear a certain resemblance to previously reported virulent phages of B. thuringiensis (Chapman & Norris, 1966; Colasito & Rogoff, 1969).
Cerebral atrophy in uraemia.

Cases of cerebral atrophy (CA) in uraemic patients were already described in 1977, as the result of a preliminary investigation on that topic (1), but the size of the problem of CA in patients under conservative or substitutive treatment is now becoming clearer (4); recent reports add up to an extraordinary high incidence (2-3-5). The term CA is used to refer to a pathological reduction of the brain mass, unquestionably due to loss of neurons (6), and axon and dendritic rearrangement and reduction (7). That this finding has become of such import in uraemia is largely attributable to the fact that non-invasive methods are now available to study the morphology of the central nervous system (CNS) computerized axial tomography (CAT) and nuclear magnetic resonance (NMR). Although in routine neuroradiology, CA corresponds to a morphological picture marked by overall enlargement of the subarachnoid spaces, the cortical sulci and the ventricular cavities, a distinction should really be made in CA of two possible, substantially different aspects: there is cortical atrophy (ca), specifically involving a reduction of the cortical mantle, with an increase in the number of the sulci, as they become easier to distinguish and their enlargement; then there is ventricular atrophy (ve), involving enlargement of the ventricular cavities. The presence of either one of these forms does not exclude the concomitant presence of the other in the same patient. This differentiation in individual patients and its prevalence and incidence in the uraemic population is not merely a nosological question: in non-uraemic CA ventricular dilatation at least has been seen to be associated with more striking mental deficits (8) although obviously such cases also occur with major ca. This pathology, concomitant with the uraemic syndrome, is not characteristic of dialytic encephalopathy or acute encephalopathic syndrome, though sporadic cases of CA have been reported in these two conditions (9). It is usually a casual finding, with no evident mental symptoms or intellectual deficiencies. The International Journal Of Artificial Organs / Vol. 10/ no. 1, 1987/ pp. 9-13
Theletrum lamothei sp. nov. (Digenea), parasite of Echidna nocturna from Cuajiniquil, Guanacaste, and other digenes of marine fishes from Costa Rica.

A new species of Theletrum is described from the intestine of two palenose morays, Echidna nocturna, collected in Cuajiniquil, Guanacaste Province, Costa Rica. The new species differs from the type species, T. fustiforme Linton, 1910 by having a subspherical pars prostatica, a subspherical seminal vesicle extending anteriorly to the anterior border of the acetabulum, by the presence of a poorly developed hermaphroditic sac, and by having a larger body size. We also report eight additional species of digeneans parasitizing marine fishes in several localities along the Atlantic and Pacific coast of Costa Rica: Bianium simonei, Didymozoinae (metacercariae), Ectenurus virgulus, Hypocreadium myohelicatum, Lecithochirium microstomum, Pseudolecithaster sp. , Stephanostomum casum, and Tergestia laticollis. In addition, we present an updated list of helminth parasites of marine fish from Costa Rica and discuss the importance of including parasites as an integral part of biodiversity inventories.
Partizipatives Produktivitätsmanagement (PPM) bei komplexen Dienstleistungen

Zusammenfassung. Es wurde ein PPM-Projekt in einer Arbeitsgruppe (N = 8) eines internationalen Marktforschungsunternehmens, die komplexe Dienstleistungen zu erbringen hat, durchgefuhrt. Die Arbeitsgruppe entwickelte in einer zweimonatigen Systementwicklungsphase ein PPM-Mess- und Feedbacksystem mit drei Aufgabenbereichen und 13 Indikatoren. Zu zwei Messzeitpunkten (monatliche Perioden) wurden zunachst Baselinedaten erhoben. Daraufhin erfolgte eine Feedbackphase uber einen Zeitraum von weiteren zwei Monaten. Im Verlauf des Projekts ergab sich eine Effektivitatszunahme von d = 0.89. Zudem wurde das Teamklima der Arbeitsgruppe untersucht. Es ergaben sich deutliche Verbesserungen auf allen vier Dimensionen (Zielorientierung, Aufgabenbewaltigung, Zusammenhalt und Verantwortungsubernahme).
Movilidad de pesticidas en aguas superficiales empleados en agricultura y riesgos para la salud humana en la zona centro del Departamento de Boyacá-Colombia

Boyaca es el Departamento de Colombia con el mayor numero de casos de cancer gastrico; recientes investigaciones sugieren un rol importante de los residuos de pesticidas en comida y una contaminacion prolongada de fuentes de agua superficial para consumo humano; esto podria generar un factor de riesgo hacia esta enfermedad; el presente estudio tiene como objetivo identificar los principales pesticidas empleados en la zona centro del Departamento de Boyaca y determinar el grado de exposicion de los agricultores a estos pesticidas; evaluando el tipo de proteccion utilizada y el tiempo de fumigacion empleado por los agricultores en sus labores diarias; ademas se establecio la dispersion de los pesticidas en una fuente de agua superficial evaluando la concentracion alcanzada en una determinada distancia y en funcion del tiempo de residencia en la fuente.