Miracle-dz/UniFAR-FTUs huggingface dataset:
Solution-Processed Phototransistors Combining Organic Absorber and Charge Transporting Oxide for Visible to Infrared Light Detection.

This report demonstrates high-performance infrared phototransistors that uses a broadband absorbing organic bulk heterojunction (BHJ) layer responsive from the visible to the shortwave infrared, from 500 nm to 1400 nm. The device structure is based on a bilayer transistor channel that decouples charge photogeneration and transport, enabling independent optimization of each process. The organic BHJ layer is improved by incorporating camphor, a highly polarizable additive that increases carrier lifetime. An indium zinc oxide transport layer with high electron mobility is employed for rapid charge transport. As a result, the phototransistors achieve a dynamic range of 127 dB and reach a specific detectivity of 5x10^12 Jones under low power illumination of 20 nW/cm^2, outperforming commercial germanium photodiodes in the spectral range below 1300 nm. The photodetector metrics are measured with respect to the applied voltage, incident light power, and temporal bandwidth, demonstrating operation at the video-frame rate of 50 Hz. In particular, the frequency and light dependence of the phototransistor characteristics are analyzed to understand the change in photoconductive gain under different working conditions.
Colorimetric Sensor Array for Human Semen Identification Designed by Coupling Zirconium Metal-Organic Framework with DNA-Modified Gold Nanoparticles.

Rapid and accurate identification of semen is critical for male infertility diagnosis and the arrangement of personalized treatment. However, the complexity and diversity of samples impose lots of restrictions in detection. To solve this problem, we propose a colorimetric sensor array in this work by coupling zirconium metal-organic framework (Zr-MOF) with single-strand DNA decorated gold nanoparticles (ssDNA-AuNPs) for the human semen identification. Because of the coordination interactions between the Zr6 clusters and the DNA phosphate backbone, as well as π-π stacking and H-bonding, Zr-MOF can absorb and precipitate AuNPs with the aid of single-strand DNA. What's more, addition of semen samples in the test solution, proteins or other contents in the samples will affect the co-precipitation of Zr-MOF and ssDNA-AuNPs. Subsequently, the color of supernatant will change and a method to identify human semen can be developed. Further studies reveal that the method can completely detect different semen cases based on the differences in inclusions, demonstrating the characteristics of simplicity, feasibility and sensitivity in the application of male infertility diagnosis.
“Feasible and effective administration of Bortezomib with Rituximab in children with relapsed/resistant B-cell precursor acute lymphoblastic leukemia (BCP-ALL): A step toward the first line”

Abstract Despite a high cure rate in childhood BCP-ALL, 20% of children still presents with relapse, mostly due to a persistent leukemic clone during the first-line treatment. In this context, obtaining a molecular remission is crucial for reaching a successful allogeneic hematopoietic stem cell transplantation. Bortezomib was effectively administered to children with resistant/relapsed (r/r) BCP-ALL. Moreover, high risk ALL is characterized by the increasing expression of CD20. For the first time we reported two children with r/r BCP-ALL who received a treatment schema including Bortezomib and Rituximab, achieving morphological and molecular remission. Children with high risk features, such as persistent minimal residual disease during induction, will benefit from this combination. Is it time to move toward the first line?
Intake and growth in transported Holstein calves classified as diarrheic or healthy within the first 21 days after arrival in a retrospective observational study

ABSTRACT Strategies that can improve health and maximize growth in the preweaning period should improve the subsequent production and longevity of replacement animals. Few data are available that quantify feed and water consumption, as well as growth, in healthy versus non-healthy calves—the objective of this study. A database of Holstein calves (<1 wk of age; n = 313) was developed to compare calves that developed diarrhea in the first 21 d after arrival from commercial farms to the research facility versus calves that remained healthy. Individual calf data from 4 experiments included daily intake of milk replacer, free water, electrolyte solution, and starter grain, as well as weekly body weight (BW) and frame measures for 21 d after arrival. Calves with a fecal score of >2 for ≥3 consecutive days over the first 21 d of each experiment were retrospectively classified as diarrheic (DIA; n = 96); the remainder were classified as healthy (HEA; n = 217). Other health issues were minimal. The likelihood of elevated fecal score occurrence and the cumulative number of days with an elevated score were greater for DIA calves than for HEA calves. The initial total protein concentration in blood did not differ between classifications. Cumulative milk replacer dry matter intake (DMI) and water consumed from milk replacer were significantly less for DIA calves than for HEA calves, because DIA calves were more likely to refuse milk replacer. Cumulative starter DMI was decreased for DIA versus HEA calves. As a result, cumulative total DMI was significantly less for DIA calves than for HEA calves. Cumulative free water intake did not differ between classifications. The DIA calves were more likely to receive electrolyte solution and have more days given electrolyte solution than HEA calves. As a result, total cumulative intake of electrolyte solution was greater in DIA calves than in HEA calves. Cumulative total water intake did not differ between classifications. Initial BW did not differ between classifications; however, a classification × time interaction for BW indicated that HEA calves were heavier than DIA calves and had greater ADG. Significant classification × time interactions for hip height and heart girth revealed that HEA calves had a larger frame size. Gain–feed ratios for both milk replacer intake and total DMI differed between classifications: DIA calves were less feed-efficient than HEA calves. In conclusion, diarrhea in young calves decreases DMI, BW gain, and feed efficiency relative to HEA calves within 21 d of arrival.
Using behavior as an early predictor of sickness in veal calves.

The objective of this study was to analyze whether changes in behavior can be a good early predictor of sickness in calves. Friesian males calves (n = 325; 30 ± 9 d of age; 65 ± 15 kg) were monitored with an activity-monitoring device from 30 to 90 d of life in 4 periods corresponding to 4 seasons. The activity-monitoring device measured number of steps, number of lying bouts, lying time, and frequency and time of visits to the feed bunk. Calf health status was monitored daily and all incidences were recorded. To compare sick and healthy calves, a matched pair design was used to assign calves into the healthy group. Day 0 was defined as the day of sickness diagnosis. For each sick calf, 3 calves with no signs of sickness during the entire period (healthy calves) on the same date, in the same season, and of similar age (±4 d) and weight at entry were identified. A multivariate linear mixed model was used from d -10 to +10 relative to the sickness diagnosis to describe differences between sick and healthy calves. A multivariate logistic regression model was used for predicting sick calves on the days before the diagnosis. Significance was declared at P < 0.05. Daily, healthy calves had 1,476 ± 195 steps, spent 185 ± 32.5 min at the feed bunk, consumed 10 ± 1.1 meals, had 19.5 ± 1.8 lying bouts, and spent an average of 978 ± 30.5 min lying. The difference in behavior between sick (n = 33) and healthy calves (n = 99) began to be evident on d -10. Sick calves had fewer steps and numbers of visits to the feed bunk on d -1 and 0 and spent less time at the feed bunk on d -10 and -1 compared with healthy calves. From d -2 to d 9, sick calves had 15% fewer lying bouts, with no difference in lying time except on d -10, when sick calves spent more time lying. The best prediction model was for d -1 and included season and age at entry as qualifying variables, and frequency of visits to the feed bunk, steps, and lying time as behavior predictors (69% sensitivity, 72% specificity, 72% accuracy, 55% false-positive rate, and 12% false-negative rate). However, an earlier prediction would be more useful to reduce the negative effect of sickness on production and welfare. The prediction model for d -10 had 67% sensitivity, 67% specificity, 67% accuracy, 60% false-positive rate, and 14% false-negative rate. Results indicate that the occurrence of sickness can be predicted in advance, and an automated alarm system could be used to identify calves at risk of becoming sick and apply a preventive treatment.
Autonomic nervous system function following exercise-induced hyperthermia

Exercise in the heat is associated with cardiovascular and thermoregulatory disturbances that can persist postexercise. The effect of orthostasis on autonomic nervous system function following exercise-induced hyperthermia (EIH) remains to date unclear. Insight into the mechanisms of control is beneficial to those encountering orthostatic challenges after activity-induced hyperthermia. We evaluated the short-term postexercise cardiovascular and thermoregulatory responses to repeated orthostatic challenges performed in a hyperthermic state and the effects of EIH on autonomic nervous system function during repeated orthostatic challenges in the early and late-stages of recovery. We conclude that following EIH, the cardiovascular system maintained arterial pressure and cardiac output during repeated 70° head-up tilts. Nonthermal baroreceptor control predominates over thermal control of cutaneous vascular conductance during postural challenges following EIH, but no effect was observed in local sweat rate. The short-term reductions in baroreceptor sensitivity and heart rate variability following EIH were re-established following a 24-h recovery period.
Full Report. Understanding long-acting reversible contraception: an in-depth investigation into sub-dermal contraceptive implant removal amongst young women in London. A report for the London Sexual Health Commissioning Programme

There has been significant focus in recent years, in the UK, on long-acting reversible contraception (LARC) and the impact that LARC use could have on reducing rates of unwanted and unintended pregnancy (NICE 2005). Long-acting reversible contraceptives (IUD, IUS, contraceptive implant, contraceptive injection) are highly effective methods of contraception. In addition they are discreet and do not require daily user compliance. However, despite these apparently positive features, LARC methods are less popular than might be expected, and there has been considerable discussion about why these seemingly convenient and effective methods have had such a low user uptake (Williamson et al 2009, Glaiser et al 2008, Tanfer et al 2000). With respect to the implant, an expensive form of contraception, work undertaken by NICE (2005) had shown geographical inconsistencies suggesting uneven access to the method. More recently, data suggest that women continue to experience uneven access, with London having the second lowest uptake of the implant in any English region.
Fatores de risco associados presso arterial elevada em adolescentes

High levels of arterial blood pressure in childhood and adolescence have been often associated with other cardiovascular risk factors apart from arterial hypertension in the adult stage of life. The present study aimed at identifying risk factors associated with high blood pressure in adolescents. The subjects were 674 adolescents from public and private schools in the city of Joao Pessoa, Paraiba. These subjects were of both sexes (i.e., 303 boys and 371 girls) and their ages spanned from 14 to 17 years old. By means of a questionnaire, information about the following aspects was gathered: a) socio-demographic status; b) physical activity levels; c) eating habits; d) body mass index; e) consumption of alcohol and smoking. Moreover, measurements of arterial pressure (AP) showed that the prevalence of high AP was 7.4 %, being higher in boys (10.2%) when compared with girls (5.1%, p < 0.01). The results of the multivaried analysis indicated that overweight adolescents displayed from five to six times more chance of having high AP than adolescents with light/normal weight (boys: OR = 5.5; CI 95% = 1.11-27.53, and girls: OR = 4.8; CI 95% = 1.51-15.45). The other variables did not seem to be associated with high AP. In this study, among the various risk factors analyzed, body overweight acted out as the only potential risk factor increasing arterial blood pressure in adolescents, irrespective of their sex and age.
Evaluation of Congenital Maxillary Growth Using Computed Tomography in Patients With Bilateral Cleft Lip and Palate

Objective: To analyze congenital lateral maxillary growth for patients with bilateral cleft lip and palate (BCLP). Design: A retrospective study. Setting: Kanagawa Children’s Medical Center. Materials: Images from computed tomography (CT) of patients with BCLP and control patients that were previously used for treatment. Main Outcome Measures: The following landmarks were used: A, the posterior most point of the piriform aperture; B, the superior most point of the acoustic meatus; C, the point at which line A-B intersects the line drawn perpendicular from line A-B to the maxillary tuberosity; and D, the apical most point of the nasal bone. The following distances were then measured using these landmarks: (1) A-B distance; (2) A-C distance; (3) A-C/A-B; (4) the angle between lines A-B and A-D (∠BAD); and (5) B-D distance. Result: Mean A-B and A-C distances and A-C/A-B were significantly smaller in the BCLP group than in the control group (P < .01 each). Mean ∠BAD was significantly larger in the BCLP group than in the control group (P < .01). Mean B-D distance did not differ significantly between groups. Conclusions: Our results indicated that the lateral maxillary segments of patients with BCLP were more posterior than those of the control group, and segment length was shorter compared to the control group on 3D-CT analysis. The lateral maxillary segments of patients with BCLP were basically suggested to originally be underdeveloped.
Central corneal thickness and intraocular pressure in patients of primary open angle glaucoma and normal population in Nepalese population: A hospital based study.

INTRODUCTION Central corneal thickness (CCT) is a powerful predictor of primary open angle glaucoma. Individualized risk assessment is critical for early diagnosis and management of glaucoma. OBJECTIVES To compare CCT and intraocular pressure in patients of primary openangle glaucoma (POAG) with those of normal population. MATERIALS AND METHODS A Comparative Cross-Sectional Study was performed in Ophthalmology department of B. P. Koirala Institute of Health Sciences, Nepal. Newly diagnosed cases of primary glaucoma (open angle, normal tension) of 18 years and above, without known systemic diseases were included. RESULTS Out of a total of 291 subjects (582 eyes), 105 subjects (210 eyes) were with primary glaucoma and 186 (382 eyes) were normal subjects. There was no significant difference in CCT between glaucomatous (533.57 μm) and normal (530.06 μm) eyes (p=0.1). Cornea was thinner (518.±18.03 μm) in eyes with severe glaucomatous damage (cup:disc ratio > 0.8) than in moderate glaucomatous damage (cup:disc ratio=0.5-0.8)(p=0.003). There was a statistically significant difference of 22.05 μm in CCT between POAG and NTG (p<0.001). A positive correlation was found between IOP & CCT in both cases and control group (p=0.000; r = 0.355, 0.254; r2 =0.126, 0.064 respectively). CONCLUSION Majority of studied Nepalese population have CCT less than 550 μm, thus increasing the risk of POAG. CCT decreases with age, and females with glaucoma have significantly thicker cornea than men. There is a significant positive correlation between CCT and IOP, and IOP will have to be adjusted for CCT for proper diagnosis and monitoring of glaucomatous damage in Nepalese population too.
Wolff's anatomy of the eye and orbit

Bony orbit and paranasal sinuses. Ocular appendages. Orbital vessels. Extraocular muscles and eye movements. Innervation and nerves of the orbit. The globe. Cornea and sclera. Anterior chamber and drainage angle. The iris. Posterior chamber and ciliary body. Choroid and uveal vessels. Lens and zonules. The vitreous. The retina. Visual pathway. Autonomic nervous system. Development of the eye. Comparative anatomy of the eye.
Comparison of slaughter performance, meat traits, serum lipid parameters and fat tissue between Chaohu ducks with high- and low-intramuscular fat content

Abstract This study was conducted to investigate the effect of intramuscular fat (IMF) on carcass traits of Chaohu ducks. Two-hundred-forty ducks were separated by sex and raised in separate pens. Slaughter performance, meat quality, and serum lipid parameters were identified. Based on IMF, samples were divided into males with high IMF (CHM) or low IMF (CLM) and females with high IMF (CHF) or low IMF (CLF). There were significant differences in the living body weight, abdominal fat ratio (%), shear force, IMF, total cholesterol (TC), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) content between female and male ducks. In addition, compared with the CLM group, the shear force (p = 0.001) was significantly greater but the lightness (p = 0.006) was lower in the CHM group. TC, HDL and LDL content were also significantly higher (p = 0.033, 0.027 and 0.012, respectively) in the CHM group. The butcher ratio (0.028), eviscerating rate (0.039) and breast meat ratio (0.028) in the CHF group was significantly lower than that in CLF group, while these parameters showed no difference between CHM and CLM. In conclusion, IMF had a significantly positive correlation with subcutaneous fat and abdominal fat and was also positively correlated with TC, HDL and LDL in Chaohu ducks.
Representing Nursing Data With Fast Healthcare Interoperability Resources

Supplemental digital content is available in the text. Healthcare communities are rapidly embracing Health Level 7's Fast Healthcare Interoperability Resources standard as the next-generation messaging protocol to facilitate data interoperability. Implementation-friendly formats for data representation and compliance to widely adopted industry standards are among the strengths of Fast Healthcare Interoperability Resources that are accelerating its wide adoption. Research confirms the advantages of Fast Healthcare Interoperability Resources in increasing data interoperability in mortality reporting, genetic test sharing, and patient-generated data. However, few studies have investigated the application of Fast Healthcare Interoperability Resources in nursing-specific domains. In this study, a Fast Healthcare Interoperability Resources document was generated for a use case scenario in a home-based, pressure ulcer care setting. Study goals were to describe the step-by-step process of generating a Fast Healthcare Interoperability Resources artifact and to inform nursing communities about the advantages and challenges in representing nursing data with Fast Healthcare Interoperability Resources. Overall, Fast Healthcare Interoperability Resources effectively represented the majority of the data included in the use case scenario. A few challenges that could potentially cause information loss were noted such as the lack of standardized concept codes for value encoding and the difficulty directly connecting an observation to a related condition. Continuous evaluations in diverse nursing domains are needed in order to gain a more thorough insight on potential challenges that Fast Healthcare Interoperability Resources holds in representing nursing data.
Understanding Preferences for Humane and Cruel Treatment of Pest Rodents in Site C, Khayelitsha, South Africa

ABSTRACT The cruel treatment of pest rodents is a neglected area of study. This paper uses a representative survey from Khayelitsha (Cape Town) to show that a minority of residents preferred rodent control to be humane but that most did not care how rats are killed and almost a fifth said they would be ‘happy’ if the rats suffered. Agreeing that animal welfare is important and having become used to the presence of rats raised the probability of support for humane rodent control and decreased support for cruel rodent control. Being concerned that rats might be linked to witchcraft increased the probability of a pro-cruel stance. These results were robust to the inclusion of measures of rodent presence in the household and socio-economic status. This highlights the importance of values (notably concern about animal welfare) and cultural beliefs – in this case concerns that rodents might be linked to witchcraft – in predicting whether respondents are likely to have a pro-cruel stance on rodent control or not. Promoting the humane treatment of pest animals in this context thus requires engaging with local culture.
Influence of early postoperative showering in undressed surgical wound for better clinical outcome

Surgeons instruct the patients to avoid postoperative bathing and dress the wounds until the sutures are removed. All wounds were sutured at the end of surgery and kept undressed. Participants received a tap water body bath where the water covered the wound after 24h of surgery. The control group were asked not to wet the dressed surgical site until wound inspection on days 3 and 5. The patients were followed up in the surgery clinic on days 14 and 30 after surgery, when age, sex and type of surgery-matched controls’ surgical site infection was significantly high in clean/contaminated and contaminated appendicectomy, breast lump excision, inguinal herniotomy and tendon repair surgeries. In contaminated appendicectomy, clean/contaminated and contaminated herniotomies postsurgical infections other than surgical site infection were significantly low in test groups. Early mobilisation, keeping the surgical wounds moist and providing a clean environment are suitable to minimise the surgical wound and other associated infections.