Miracle-dz/UniFAR-FTUs huggingface dataset:
A comparative analysis and design study of cross layer scheme based algorithm to increase the Qos performances in wireless communication

Mobile an ad hoc network is a self organizing wireless network for built spontaneously to connect the mobile devices. It does not require any fixed infrastructure due to no wired backbone. It is suitable to use in the environment that have need of on the fly set-up. Every host is a router and packet forwarder. Each node may be mobile, and topology changes frequently and unpredictably due to the arbitrary mobility of mobile nodes. This aspect leads to frequent path failure and route rebuilding. Routing protocol development depends on mobility management, efficient bandwidth and power usage which are critical in ad hoc networks. Cross layer scheme is the new method for wireless mobile devices become to increase the capacity network. This paper, proposed a new cross layer scheme based algorithm to increase the throughput in MANETs. This present three schemes to reduce packet retransmission ratio by distribution signal information between physical layer and MAC layer, and to discuss the frequent route failures in MANET by identify shortly to be broken links instead of prediction of received signal power, To find optimized route maintenance by taking into consideration of Bandwidth, Delay which results by improvement of QoS. The performance of cross layer process for all the schemes simulation are carried out to evaluate network performance using network simulator NS-2 based on the basic parameters like Throughput, Jitter and packet delivery ratio (PDR) in term of number of nodes when various pause times.
Motives for Participation in On-Line Open Innovation Platforms

The increasing need to compete on innovation, together with the prevalence of IT in our social and economic interactions has led to a globalization in the sourcing of innovation. One of the best examples of this process is the raise of on-line Open Innovation Intermediaries as both markets for innovation and a locus where innovative solutions are devised. Therefore, understanding what are the main motivations that drive the participation of people into these intermediaries is increasingly relevant for organizations that seek to tap into the massive information potential. This is why this paper aims to develop an understanding on this matter with a modified version of Theory of planned behavior (TPB).
Profit sharing in audit partnerships

Academics call the problem that arises when individuals in a partnership take actions inconsistent with the partnership's collective interest the "moral hazard problem". This thesis examines how an audit partnership (i.e., partners as a whole) uses profit sharing rules to induce optimal partner behavior in performing various tasks, and thereby maximize the welfare of the partnership. The analysis is undertaken in different market structures: a competitive market and an oligopolistic market, which are intended to capture the different markets for the non-Big Five audit firms and the Big Five audit firms. Non-cooperative game theory is used to analyze the strategic interaction of partners within a partnership, as well as the strategic interaction of firms when the market is an oligopoly. In the oligopolistic market setting, it is assumed that clients are different in that the efficient audits of different types of clients require different effort profiles (i.e., different mix of auditors' effort-inputs); however, it is too costly, if not impossible, for an independent party like a court to verify each client's type, and thus client type cannot be used for partner compensation purposes. Under this assumption, I derive conditions under which there exists an equilibrium where audit firms strategically choose different profit sharing rules to specialize in different types of clients, and thereby earn positive economic profits. As a result of specialization, firms have different clienteles, and may provide audits of different quality and charge different audit fees for the same type of client. The analytical results help explain the observed differences in compensation plans among the Big Five audit firms, and provide insights into the differences in the audit services provided by the Big Five firms. This thesis also provides some empirical evidence consistent with the theory developed in this study.
Hearing threshold levels for a population of 11 to 35 year old Australian females and males

Abstract Objective: Detailed information on the hearing threshold levels (HTLs) of young Australians was gathered as part of a large-scale study of the relationship between HTL and leisure-noise exposure in young Australians. Design: HTL data for the study population (18–35 year olds) was carefully collected, as well as otoscopy, tympanometry, contra-lateral acoustic reflexes, and otoacoustic emissions (transient and distortion product), together with a comprehensive hearing health history – both past and present. Study sample: The sample cohort consisted of 1407 individuals, females and males. Results: Prior to analysis, HTL data were filtered according to both a ‘Low’ and ‘High’ set of exclusion criteria. The results obtained for both high-screen and low-screen datasets were around +5 dB above the traditionally accepted values of audiometric zero. This is consistent with previous published reports. Conclusion: Comparison with ‘ISO 7029 Acoustics: Statistical distribution of hearing thresholds as a function of age’ indicated that threshold values for this dataset have a similar distribution to those of the Standard. This data provides a suitable reference HTL (‘normative’) database for young Australians.
Advances in Brief The Retinoblastoma Gene in Breast Cancer : AlÃ-eleLoss Is Not Correlated with Loss of Gene Protein Expression 1

The significance of the retinoblastoma gene (RB) in the development of human breast cancer remains unclear. In the present study, loss of heterozygosity (LOH) in Kit was found in 26% of 90 informative primary breast tumors and was correlated to DNA nondiploidy, a high S-phase fraction, and LOH at chromosome 17pl3.3. However, alÃ-eleloss was not associated with loss of RB protein (pRB) expression. Low to absent levels of pRB were found in 15% of 73 immunoblot analyzed tumors, most of which manifested retained heterozygosity in RB. Conversely, tumors exhibiting LOH showed often high pRB expression. Our data suggest that RH may be involved in the pathogenesis of some breast tumors, as evidenced by the absence of pRB, but that this alteration is acquired by mechanisms other than the unmasking of a recessive mutation by alÃ-eleloss. LOH in RB may be merely a stochastic event in the unstable genome of aneuploid, rapidly proliferating cells or, alternatively, reflect the presence of an adjacent tumor suppressor gene.
Modelling critical success factors of business process reengineering and business performance of Nigerian oil and gas companies

Business process reengineering (BPR) is a fundamental rethinking and radical redesign of business processes to achieve dramatic improvements in critical contemporary measures of performance such as cost, quality, speed and services (Al-Mashari and Zairi, 1999). This paper provides a holistic view of the BPR implementation process, by reviewing the hard and soft factors that cause success and failure for BPR implementation, as well as, examine the effectiveness of the critical success factors (CSFs) of BPR on both primary (operational) and secondary (organisational) measures of business performance in Nigerian oil and gas industry. The aim was achieved through an empirical study involving the administration of 650 self-administered questionnaires to a randomly selected senior and management staff of eight (8) re-engineered oil and gas companies in Nigeria. Using the framework from Khong and Richardson (2003), several hypotheses were tested, via structural equation modelling (SEM). Using SEM, multivariate analyses were mathematically represented in a single equation, and findings from this study confirmed that BPR had significant association on business performance of Nigerian oil and gas companies.
Association of the RIP2 gene with childhood atopic asthma.

BACKGROUND Receptor-interacting protein (RIP)-2 is a serine/threonine kinase containing a caspase recruitment domain (CARD) that is involved in the Toll-like receptor-signaling pathway. Although associations between endotoxin exposure or respiratory infection and asthma have been recognized, the genetic influences in these conditions are unclear. The aim of our study was to examine whether polymorphisms or haplotypes in RIP2 were associated with childhood atopic asthma in a Japanese population. METHODS We screened the RIP2 gene for polymorphisms by direct sequencing and characterized the linkage disequilibrium (LD) mapping of the gene. Seven variants were genotyped in childhood atopic asthma (n = 300) and normal controls (n = 637) . We conducted case-control and case-only association studies between the variants and asthma-related phenotypes. Haplotype association analyses were also performed. RESULTS A total of 31 variants were identified and none of the alleles or haplotypes of RIP2 were associated with asthma susceptibility. In the case-only study, an association between an RIP2 promoter polymorphism and childhood severe asthma (P=0.0032; odds ratio (OR) 3.37, 95% confidence interval (CI) 1.45-7.87) was observed. CONCLUSIONS Although polymorphisms in RIP2 are not likely to be associated with the development of asthma, the genetic variants might contribute to asthma severity in the Japanese population.
[High-density lipoproteins (HDL) size and composition are modified in the rat by a diet supplemented with "Hass" avocado (Persea americana Miller)].

PURPOSE To determine the effects of dietary avocado on HDL structure and their associated enzyme, paraoxonase 1 (PON1). METHODS Fifteen Wistar male rats received avocado as part of their daily meal (5 g by 17.5 g chow diet), keeping the caloric intake similar to the control group (n=15) that received their usual chow diet. After 5 weeks, HDL were isolated by sequential ultracentrifugation and their size and chemical composition were analyzed. PON1 was determined in serum spectrophotometrically using phenylacetate as substrate. RESULTS Rats that received avocado had about 27% lower triglycerides plasma levels whereas their HDL-cholesterol was 17% higher as compared to control group. The mean HDL Stokes diameter was significantly lower in avocado group (11.71 +/- 0.8 vs. 12.27 +/- 0.26 nm, in control group, p < 0.05). The HDL size decrease was associated to a lower content of protein, particularly of apo Al, with a concomitant higher proportion of phospholipids in HDL isolated from avocado group. HDL structural modifications induced by avocado were not related to modifications of LCAT and PLTP activities, but occurred in parallel with higher serum levels of PON1 activity when compared to the controls (57.4 +/- 8.9 vs. 43.0 +/- 5.6 micromol/min/mL serum, p < 0.05). CONCLUSIONS The inclusion of avocado in the diet decreased plasma triglycerides, increased HDL-cholesterol plasma levels and modified HDL structure. The latter effect may enhance the antiatherogenic properties of HDL since PON1 activity also increased as a consequence of avocado.
Molecular cloning and expression of Chlamydia trachomatis major outer membrane protein antigens in Escherichia coli

DNA obtained from Chlamydia trachomatis (serovar L2) was partially digested with DNase I and inserted into the beta-galactosidase gene of bacteriophage lambda gt11. Seven recombinants were selected that produced immunoreactive fusion proteins which were detected with anti-C. trachomatis rabbit serum. One recombinant, designated lambda gt11/L2/33, reacted with various monoclonal antibodies that recognize species-, subspecies-, and type-specific determinants on the chlamydial major outer membrane protein (MOMP). Immunoblot analysis of a lambda gt11/L2/33 lysogen revealed a fusion protein that expressed a approximately 15,000-dalton carboxyl-terminal peptide of the chlamydial MOMP. This moiety of the MOMP possesses epitopes responsible for each of the unique reactivities demonstrated by anti-MOMP monoclonal antibodies. The lambda gt11/L2/33 recombinant contained a 1.1-kilobase DNA insert which hybridized to DNA isolated from each of the 15 C. trachomatis serovars.
The Lived Experience of Peripheral Neuropathy after Solid Organ Transplant

Background The immunosuppressants required after transplant cause peripheral neuropathy with an incidence of 10% to 60%. Peripheral neuropathy adversely affects health-related quality of life in other populations. Objective To describe the lived experience of peripheral neuropathy after solid organ transplant. Design A qualitative phenomenological study with semistructured interviews. A purposive sample of 7 solid organ transplant recipients with peripheral neuropathy was recruited from 2 transplant clinics at a large Midwest tertiary care center. Interviews were audio taped and transcribed verbatim. Data were analyzed line-byline and coded by using HyperResearch 2.0. Results Although participants' experiences were similar to those reported by others with peripheral neuropathy, there were also unique differences. Unique to this population was unexpected onset, rapid escalation of symptoms, lack of provider monitoring, and poor provider response to reported symptoms. Their experience demonstrated that peripheral neuropathy diminished health-related quality of life. Four themes emerged from the data: (1) nothing is supposed to happen after transplant; (2) neuropathy causes me more problems than my heart; (3) maybe there is something that could help; and (4) I've learned to live with certain limitations. Conclusion Development of or worsening of peripheral neuropathy after solid organ transplant may decrease health-related quality of life. Follow-up care should include vigilant monitoring for signs of peripheral neuropathy. Providers need to provide early treatment, education, support, empathy, and understanding.
ISSUES OF CLOUD SECURITY AND ITS IMPLICATIONS

Cloud computing provides an effective computing model for institutions to access information technology and related functions with minimal investment and makes use of the resources to the maximum extent. The reduced complexity and cost of Cloud computing has attributed to it’s popularity and success. The users of this phenomenon range from an individual customer to huge organizations. Though there has been major advances in cloud computing, the security concerns surrounding it cannot be ignored and remedial measures has to be taken to ensure the confidentiality and the integrity of data stored in the cloud. Hence, it is inevitable to obtain a thorough understanding of the risks and threats involved in cloud computing along with the possible remedies before it is implemented by any stake holder. In this paper the authors have provided a comprehensive understanding of the issues in cloud security, it’s implications and the various remedial measures to address the same. A critical observation of the security of cloud is undertaken from the perspective of the cloud architecture, cloud stakeholder and cloud characteristics. The prime security issues that have been scrutinized in this paper include the security with respect to cloud carrier, malware injection problem, accountability problems in cloud, challenges in cloud integrity, securing data transmission in cloud, elasticity, cloud multi-tenancy, service level agreement and compromise on the integrity of the information in cloud. The possible counter measures to these issues have also been highlighted in this paper. There are number of unresolved issues that need to be dealt with respect to security and privacy in a cloud computing environment. This paper aims to elaborate and analyze the numerous threats faced and also provide solutions for most of the mentioned problems.
GESTION DE ALMACENAMIENTO: VINCULACION Y UTILIACION DE LOS SISTEMAS DE INFORMACION

The management of the supply chain is a field that has been investigated with knowledge in all areas of industry, concepts and research about related every link in the chain, is based on the conceptual framework and existing theories along the history; research methods employed are mostly analytical, conceptual, empirical studies and case studies. This article provides an overview of warehouse management based on the implementation of efficient systems and technology, ICT implementation, and all the tools that help streamline operations, reducing costs, and improving the flow of information. Recognizes the major obstacles to implementation, costs and outcomes in the structure of the warehouse processes. Warehouse Management in the SCM helps control, storage and distribution of products and information to meet the needs of customers at the lowest cost and with a high level of service. Describing that there are different processes and systems in warehouse management including: receiving, picking, storage, packaging and delivery, it is recommended to perform the analysis of the type of product to be stored, storage capacity and functionality of the available ICT tools demand, location and characteristics of customers orders tending to deliver the lowest cost.
Preismanagement : Strategie, Analyse, Entscheidung, Umsetzung

In vielen Märkten besitzt der Preis die zentrale Bedeutung, um Produkte erfolgreich abzusetzen. Insofern sehen sich Unternehmen immer häufiger dazu veranlasst, den Preis als Waffe im Kampf um die Gunst der Kunden einzusetzen. Folglich steigt die Notwendigkeit, dass sich Manager auf allen hierarchischen Ebenen mit der Preisbildung befassen. InAnbetracht dieser Umstände erscheint die 3. Auflage von Simon und Fassnachts „Preismanagement“ genau zum richtigen Zeitpunkt. Dieses Werk besticht durch ein hohes theoretisches Niveau der Argumentation und durch eine Fülle praktischer Anwendungsbeispiele, die es dem Leser ermöglichen, wissenschaftliche Methoden für die Preisentscheidung kennen zu lernen und deren Relevanz für das Preismanagement einzuschätzen. Insofern mag man diesem Werk attestieren, dass es das Standardwerk des Preismanagements bildet. Ein Vergleich mit der 2. Auflage zeigt, dass einige neue Aspekte hinzugekommen sind. Beispielsweise spielt die Prozessperspektive nun eine zentrale Rolle. Es geht den Autoren darum, nicht nur über Preiskalküle zu schreiben, sondern auch den Prozess von der Strategie über die Analyse bis hin zur Preisentscheidung zu verdeutlichen. Dieser Beitrag ist lobenswert, da viele Unternehmen unsystematisch die Preise ihrer Produkte bilden, häufig ausgelöst durch Kostenveränderungen oder Wettbewerberreaktionen. Gerade im Hinblick auf die Implementierung eines systematischen Prozesses der Preisbildung unter Berücksichtigung aller Preisdeterminanten und der Antizipation (sofern möglich) zukünftig beabsichtigter Preisanpassungen besteht in der Praxis erheblicher Nachholbedarf – hier leistet das Werk einen bedeutenden Beitrag.
Improving Branch Prediction Related WCET Abstract Interpretation

In this paper we refine a Markovian model previously applied to modelize a subset of dynamic branch predictors related WCET delays, in order to take the finiteness of Branch History Table (BHT) into account. The base of the model allows the modeling of a deterministic or non deterministic automaton or set of automata thanks to a Markovian model. We previously applied this formalism to cache related delay and cache related preemption delays and simple dynamic branch prediction with infinite BHT. Now we would like to take into account the finiteness of the BHT in the previous model in order to estimate extend our model of static analysis of Worst Case Execution Time (WCET). For illustration, we chose the case of a dynamic prediction based on a two bit saturating counter, with a LRU policy for replacement policy.
Southern blot analysis of clonal rearrangements of T-cell receptor gene in plaque lesion of mycosis fungoides.

T-cell populations of 22 plaque lesions from seven mycosis fungoides patients were studied for clonal rearrangement of the beta chain of the T-cell receptor (T beta) gene. All plaque lesions employed in this study showed clinically similar appearance. Histologically, all the biopsy specimens showed epidermotropism and the dermal infiltration of mononuclear cells including atypical cells. Histochemically, the majority of the infiltrated cells had surface markers of helper T cells. DNA extracted from skin lesions, peripheral lymphocytes, and lymph nodes revealed that the monoclonal expansion of T cells was different among patients and lesions. DNA extracted from the two skin lesions of case 1 revealed a clonal expansion of T cells. The rearranged bands persisted for about 1 year. In contrast, all lesions from cases 3-7 showed no rearranged band. Interestingly, three lesions from case 2 showed mixed type results, i.e., the monoclonal expansion of T cells was detected in one lesion but not in the other two lesions. Time course study of case 2 revealed that the same rearranged band became detectable in all three skin lesions and a lymph node about 1 year later. These results suggest that in plaque lesions of mycosis fungoides, there are various stages of detectable monoclonality of infiltrating cells, although the clinical appearance of the plaques was similar, and that the variety of monoclonality may reflect the long clinical course of this disease.
Single‐ and Multiple‐Dose Pharmacokinetics and Dose Proportionality of the Psychotropic Agent Paliperidone Extended Release

Paliperidone extended‐release tablet (paliperidone ER) is a centrally active dopamine D2‐ and serotonergic 5‐HT2A‐receptor antagonist that is registered for the treatment of schizophrenia. The controlled rate of release of paliperidone from the ER formulation is designed to have a slower absorption rate, which results in gradual ascending plasma concentrations with observed maximum plasma concentrations occurring at 24 hours after dosing on the first dosing day. On subsequent treatment days, the ER formulation provides minimal fluctuations in plasma concentrations. Paliperidone is eliminated with a terminal half‐life of approximately 24 hours. Steady state is achieved after 4 daily doses. Paliperidone ER exhibits time‐invariant pharmacokinetics. It shows a 3.5‐fold accumulation upon steady state, mainly caused by the controlled release characteristics of the formulation. Paliperidone ER displays dose proportionality over the dose range of 3 to 15 mg; the 90% confidence intervals of the pairwise dose comparisons are all included in the 80% to 125% bioequivalence limits.
Bye bye! : Exploring the psychological contract and commitment of different generations of hospitality workers

High turnover rates are a common and costly problem for hospitality companies, even more so as a new generation of workers, Generation Y, enters the workforce. The present study explores a number of antecedents to this turnover in the light of generational differences. Data was collected in 20 hotels (N=359) of a hotel chain using an online survey. Results show generational differences in psychological contract, with Baby Boomers valuing work-life balance, Generation X job security and Generation Y stimulating jobs. Also, Generation Y demonstrates significantly lower levels of commitment and higher turnover intentions. These results indicate that we may want to redesign jobs around these new workers’ values and expectations if we want to better retain staff in the future.