Miracle-dz/UniFAR-FTUs huggingface dataset:
A ROTAÇÃO DE PESSOAL E A GESTÃO DE RECURSOS HUMANOS NA HOTELARIA: O CASO DA REGIÃO DO PORTO E NORTE DE PORTUGAL

A gestao das empresas do sector turistico, nomeadamente a hotelaria, enfrenta o problema de assegurar uma performance superior por parte dos seus Recursos Humanos, muitas vezes recrutados por uma epoca, tradicionalmente mal pagos e sujeitos a uma elevada taxa de rotacao de pessoal. Face a esta problematica, o presente trabalho pretende abordar a dimensao que a rotacao de pessoal tem para as organizacoes do sector hoteleiro da regiao do Porto e Norte de Portugal, e ainda, avaliar ate que ponto esta se relaciona, ou nao, com a existencia de efectivas praticas de gestao de recursos humanos. Sao colocadas duas hipoteses que permitem concluir acerca da forma como praticas efectivas de recursos humanos estao correlacionadas com a rotatividade, bem como de que forma a dimensao da unidade hoteleira explica a existencia /inexistencia de praticas de Gestao de Recursos Humanos.
Integrated Product Policy and Environmental Product Innovations: An Empirical Analysis

The European Commission has recently stepped up its promotion of the "Integrated Product Policy". The objective of the IPP is to support the realisation of environmental product innovations and thus to achieve a broad reduction of all environmental impacts throughout a product's life cycle. Based on a unique company level data set for the German manufacturing sector, this paper empirically examines the relationship between environmental organisational measures regarded as IPP measures by the European Commission and environmental product innovations. According to the econometric analysis, the certification of environmental management systems has a significantly positive effect on environmental product innovations. Waste disposal measures or product take-back systems appear to be an even more important driver of environmental product innovations. The econometric analysis also shows that other factors that have been suggested in the literature, such as environmental policy, technology push and market pull, as well as other specific company characteristics have a significantly positive influence on environmental product innovations. According to the descriptive analysis of environmental product innovators, economic aspects (i.e. higher prices) rather than soft factors appear to be the major obstacles to the commercial exploitation of environmental products and thus also to environmental product innovations.
Effect of increasing concentrations of lysine and length of culture time on the relative growth rate ( OD value ) of bovine mammary epithelial cells

Xuemei Nan,* Dengpan Bu,* Xiyan Li,* Jiaqi Wang, Hongyang Wei, Han Hu, Lingyun Zhou, and Juan J. Loor State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Haidian District, Beijing, Peoples Republic of China; and Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, Illinois
Text stream processing

The aim of this tutorial is to present an overview of text stream processing starting with a description and properties of text streams, and continuing with a series of text processing techniques and their applicability to text streams. Among the text processing techniques we are going to describe entity extraction and resolution, event and fact extraction, word sense disambiguation, sentiment analysis, summarization, social network analysis, all in the context of text streams. The goal is to present the list of problems and challenges arising when processing text streams and to show how they can be approached using text mining, natural language processing and semantic analysis techniques and tools. The tutorial will describe available approaches and show some demos on text data streams, using publicly available tools.
[Retrospective evaluation of the ten-year experience of a single coeliac centre].

UNLABELLED Coeliac disease (gluten-sensitive enteropathy, sprue) is a chrocic disorder of the small bowel leading to malabsorption. AIMS charts of all patients with coeliac disease treated at the 2nd Department of Medicine, Semmelweis University were evaluated. PATIENTS AND METHODS The authors retrospectively analysed the results of a total of 132 patients with coeliac disease (107 females and 25 males; mean age, 37 years; median, 35 years; range, 19-78 years) attending the centre between 1999 and 2010. The authors routinely performed the following investigations in patients with suspected coeliac disease: multiple biopsies taken from the duodenum, tissue transglutaminase antibody or endomysial antibody based serology, body mass index calculation, osteodensitometry, evaluation of disorders associated with coeliac disease, family history for coeliac disease, and implementation of family-screening for coeliac disease given the agreement of the index patients. RESULTS Histological samples were available in 101 cases, and distributions of data according to the Marsh-classification were as follows: negative in 9%, M3a in 27%, M3b in 18%, and M3c in 46% of cases, respectively. Serological results were available in 117 cases. 93/117 (79%) showed seropositivity. Body mass index was calculated for 95 patients, and the mean value for males was 22.4 kg/m² (range, 17-30.3 kg/m²), whereas the mean value for females was 20.7 kg/m² (range, 15.2-30.4 kg/m²). Osteodensitometry was performed in 90 patients; 45 patients (50%) proved normal, 31 (34%) had osteopenia, and 15 (26%) had osteoporosis. Coeliac disease associated disorders were present in 45/132 patients (34%; 6 males). Associated disorders were as follows: 15 dermatitis herpetiformis Duhring, 15 thyroid diseases (5 hypo- and 10 hyperthyroidism), 6 Crohn's disease, 3 selective IgA-deficiency, 2 endometrioses, 1 systemic lupus erythematosus, 1 myasthenia gravis, and 1 type-1 diabetes mellitus. Sixty-four of the 132 index patients brought 133 first-degree relatives for family screening (serology), where 26/133 (19.5%; 17 females) first-degree relatives proved to suffer from coeliac disease. CONCLUSIONS The age distribution of this cohort demonstrates that coeliac disease can present at any age. Similarly to those of other coeliac disease centres, female predominance is significant. Histology usually showed advanced villous atrophy. Serological results were usually in conjunction with the histological results and proved to be useful for monitoring dietary compliance and for accomplishing family screening. The mean body mass index values were in the normal range confirming that adult patients with coeliac disease are usually not malnourished. The 20% prevalence of coeliac disease among first-degree relatives underlines the necessity of family screening.
Functional defect caused by the 4544G>A SNP in ABCC2: potential impact for drug cellular disposition

Objectives ABCC2 contributes to the active cellular efflux of several endogenous and exogenous compounds. The 4544G>A (rs8187710) single nucleotide polymorphism (SNP), which is coding for a C1515Y substitution, has been previously associated with susceptibility to cholestatic liver disease, doxorubicin cardiotoxicity, nonalcoholic fatty liver disease, decreased graft function after renal transplantation and tenofovir-induced proximal nephropathy. It is also involved in differential flavopiridol disposition and increased lopinavir (LPV) cellular accumulation in vivo. The aim of the present study was to investigate whether the 4544G>A SNP causes alterations in ABCC2-mediated transport towards different substrates and to explore the underlying molecular mechanisms. Methods Human embryonic kidney cells (HEK293) were stably transfected with full-length ABCC2 cDNA coding the wild-type (4544G) or the variant (4544A) ABCC2 allele. Accumulation and efflux assays were carried out with three different substrates and kinetic parameters were then compared between wild-type and variant HEK293-transfected clones. The vanadate-sensitive ATPase activity of the wild-type and the variant ABCC2-transfected clones was assayed in isolated membranes vesicles. Results At a comparable expression level, the ABCC2 4544A clone showed higher accumulation of LPV, calcein and carboxyfluorescein diacetate as well as reduced ABCC2-mediated efflux of LPV compared with the ABCC2 4544G clone. The 4544G>A SNP impaired ABCC2 ATPase activity, which likely explains the reduced efflux activity of the 4544A clone. Conclusion The C1515Y amino acid substitution caused by the 4544G>A SNP in ABCC2 impairs its ATPase activity and is associated with higher cellular accumulation of ABCC2 substrates.
Inhibition of von Willebrand factor-GPIb/IX/V interactions as a strategy to prevent arterial thrombosis

Although drugs exist for the primary and secondary prevention of thrombosis, more potent antiplatelet drugs with sufficiently wide therapeutic windows to avoid bleeding complications are needed. Both academic and pharmaceutical laboratories are working to develop such drugs. This chapter reviews the potential of inhibiting interactions between von Willebrand factor (vWF) and the second most abundant receptor on the platelet, the glycoprotein (GP) Ib/IX/V complex, interactions that are essential for the activation of circulating platelets, contacting a vessel wall injury. Although still at the level of preclinical testing, this area is expected to progress quickly during the next few years, also in view of the three-dimensional structural information that has recently become available and that allows a molecular understanding of vWF binding to the GPIbα chain of the GPIb complex.
Visualizing historical content of web pages

Recently, along with the rapid growth of the Web, the preservation efforts have also increased. As a consequence, large amounts of past Web data are stored in Web archives. This historical data can be used for better understanding of long-term page topics and characteristics. In this paper, we propose an interactive visualization system called Page History Explorer for exploring page histories. It allows for roughly portraying evolution of pages and summarizing their content over time. We use a temporal term cloud as a structure for visualizing prevailing and active terms appearing on pages in the past.
Lobular Neoplasia within a Myoid Hamartoma of the Breast

M yoid hamartomas of the breast are a rare subtype of mammary hamartoma in which a significant smooth muscle component is identified within the stroma of the lesion. Neoplastic change in mammary hamartomas is exceedingly rare, with only a few cases reported in the literature. A 44-year-old woman presented with a palpable breast mass which on macroscopic and microscopic examination had all the classical features of a mammary hamartoma of myoid type (Figs 1–4). Foci of lobular neoplasia were identified within the hamartoma, as shown in Figure 5. High-grade ductal carcinoma in situ (DCIS) was identified in the contralateral breast. This case emphasizes the need for careful examination of all apparently benign breast lesions in order to exclude coexistent neoplastic change.
Nonstate Global Governance: Is Forest Certification a Legitimate Alternative to a Global Forest Convention?

When traditional forms of multilateral governance fail to materialise, is nonstate governance a viable alternative? This problem besets the forestry issue area, where repeated attempts to forge a binding international convention to manage the use and preservation of forests have failed (Wang 2001; Dimitrov 2003). Most relevant states now strongly oppose a global forest convention, including some that previously voiced support. Moreover, even prominent nongovernmental organizations (NGOs) have withdrawn their support, fearing a convention might do worse at promoting sustainable forest management than no treaty at all. In the wake of this failure, voluntary forest certification and eco-labelling schemes sponsored by environmental NGOs or forest company and landowner associations have arisen to fill this governance gap. Can such schemes gain acceptance as a viable alternative to a global forest convention? The central argument of this chapter is that as a nonstate form of governance, transnational forest certification schemes require political authority beyond the state to succeed. In the abstract, power, legitimacy, and community constitute political authority (Bernstein 2003). In other words, authority exists when a community or audience authorises commands to which it feels bound, empowering those rules and, possibly, mechanisms to enforce them. But in the realm of global governance, especially in cases where hard law is absent, legitimacy takes on added importance because, by definition, nonstate governance schemes lack the traditional enforcement capacities associated with the sovereign state — the traditional site of authority in the international system where power, legitimacy, and authority appeared fused. Although one should always be sensitive to the importance of power for political authority, including where it resides and how it manifests, the decoupling of coercive force and legitimate rule is the most striking feature of new sites of authority found in contemporary global governance. According to James Rosenau, ‘the essence of [new sites of authority] is that they derive their legitimacy from the voluntary and conditional participation of individuals who can revoke their consent at any time’ (Rosenau 2003). 2 This chapter
Listeriosis en embarazada: reporte de un caso

Listeria monocytogenes (Lm), es una especie ampliamente distribuida en la naturaleza, ha sido aislada de numerosos animalesy es capaz de causar enfermedad en el humano, especialmente cuando hay condiciones predisponentes. Son susceptibles las mujeresembarazadas y sus fetos, ancianos e individuos inmunosuprimidos. La listeriosis durante el embarazo, puede causar infeccion intrauterinaresultando en complicaciones severas como aborto espontaneo, parto pretermino e infeccion en neonatos, con alta morbi - mortalidad.Presentamos un caso de una paciente de 39 anos de edad con 13 semanas de embarazo, a la cual se le realizo la tecnica del cerclaje. Posteriormente,presento un cuadro de meningitis bacteriana. Se realizaron cultivos de liquido cefalorraquideo, sangre y orina, entre otros;lograndose el aislamiento de Lm a partir de los hemocultivos. Finalmente fue trasladada a otra institucion para drenaje ventriculo peritoneal,donde fallecio. Este es el primer caso de diagnostico de infeccion severa por Lm en una embarazada en la Maternidad ConcepcionPalacios (MCP) de la ciudad de Caracas-Venezuela, reportado en la literatura.
Hierarchical Image Segmentation Using a Combined Geometrical and Feature Based Approach

This paper presents a fully automatic segmentation algorithm based on geometrical and local attributes of color images. This method incorporates a hierarchical assessment scheme into any general segmentation algorithm for which the segmentation sensitivity can be changed through parameters. The parameters are varied to create different segmentation levels in the hierarchy. The algorithm examines the consistency of segments based on local features and their relationships with each other, and selects segments at different levels to generate a final segmentation. This adaptive parameter variation scheme provides an automatic way to set segmentation sensitivity parameters locally according to each region's characteristics instead of the entire image. The algorithm does not require any training dataset. The geometrical attributes can be defined by a shape prior for specific applications, i.e. targeting objects of interest, or by one or more general constraint(s) such as boundaries between regions for non-specific applications. Using mean shift as the general segmentation algorithm, we show that our hierarchical approach generates segments that satisfy geometrical properties while conforming with local properties. In the case of using a shape prior, the algorithm can cope with partial occlusions. Evaluation is carried out on the Berkeley Segmentation Dataset and Benchmark (BSDS300) (general natural images) and on geo-spatial images (with specific shapes of interest). The F-measure for our proposed algorithm, i.e. the harmonic mean between precision and recall rates, is 64.2% on BSDS300, outperforming the same segmentation algorithm in its standard non-hierarchical variant.
Isolation and Characterization of cDNAs Corresponding to an Additional Member of the Human Histone Deacetylase Gene Family*

Several human cDNAs encoding a histone deacetylase protein, HDAC3, have been isolated. Analysis of the predicted amino acid sequence of HDAC3 revealed an open reading frame of 428 amino acids with a predicted molecular mass of 49 kDa. The HDAC3 protein is 50% identical in DNA sequence and 53% identical in protein sequence compared with the previously cloned human HDAC1. Comparison of the HDAC3 sequence with human HDAC2 also yielded similar results, with 51% identity in DNA sequence and 52% identity in protein sequence. The expressed HDAC3 protein is functionally active because it possesses histone deacetylase activity, represses transcription when tethered to a promoter, and binds transcription factor YY1. Similar to HDAC1 and HDAC2, HDAC3 is ubiquitously expressed in many different cell types.
Well-Being Analysis of Wind Integrated Power Systems

The paper presents well-being analysis of wind integrated electric power generating systems. An approach is presented for calculating well-being indices which gives much faster results than previously published methods. The link between the unit commitment risk criterion (UCRC) and system healthy state probability (HSPC) is illustrated using two different test systems. The method should prove useful in the decision making process of choosing an appropriate UCRC. The proposed approach extends the application of probabilistic techniques in operating reserve evaluation and determination.
Relevance of microbial coculture fermentations in biotechnology

The purpose of this article is to review coculture fermentations in industrial biotechnology. Examples for the advantageous utilization of cocultures instead of single cultivations include the production of bulk chemicals, enzymes, food additives, antimicrobial substances and microbial fuel cells. Coculture fermentations may result in increased yield, improved control of product qualities and the possibility of utilizing cheaper substrates. Cocultivation of different micro‐organisms may also help to identify and develop new biotechnological substances. The relevance of coculture fermentations and the potential of improving existing processes as well as the production of new chemical compounds in industrial biotechnology are pointed out here by means of more than 35 examples.
Intent to immunize among pediatric and family medicine residents.

OBJECTIVE To determine whether contraindications to immunization are inappropriately broadened for children with a fever or a neurologic condition. PARTICIPANTS Pediatric and family medicine residents (N = 52 and 23, respectively) at the University of Rochester (NY). DESIGN Cross-sectional survey. Residents rated how likely they would be to administer a diphtheria-tetanus-pertussis or measles-mumps-rubella vaccine in 17 clinical scenarios according to a rating scale ranging from 1 (never) to 5 (always). For all scenarios, the immunization was recommended by the American Academy of Pediatrics or the Immunization Practices Advisory Committee. RESULTS In only five and three of 17 scenarios would 90% or more of the pediatric residents and family medicine residents, respectively, have administered an immunization. For diphtheria-tetanus-pertussis vaccine, pediatric residents reported a lower likelihood of vaccinating a 2-month-old child with a low fever (temperature, 38.1 degrees C) than an afebrile child (mean score, 3.0 vs 4.7; P < .01). A 2-year-old child with idiopathic epilepsy, a 2-month-old child with intraventricular hemorrhage, and a 2-month-old child who had a parent with a seizure disorder each had a lower reported likelihood to be vaccinated than a same-aged child without a neurologic condition (2.8 vs 4.5; 4.1 vs 4.7; and 4.3 vs 4.7, respectively; each P < .01). For measles-mumps-rubella, pediatric residents reported a lower likelihood of vaccinating a 15-month-old child with a low fever than an afebrile child (4.2 vs 4.9; P < .01). A child with a progressive neurologic disease had a lower reported likelihood to be vaccinated than a child without a neurologic condition (3.5 vs 4.9; P < .01). CONCLUSIONS Residents reported a lower likelihood of immunizing children with a fever or neurologic condition. Such practice styles may contribute to underimmunization. Residents need to be educated regarding which medical conditions contraindicate an immunization.
EM algorithm updates for dimensionality re - duction using automatic supervision

A device for positioning a metal sheet on a transfer conveyor comprises a support surface for the sheet, guides extending parallel to the conveyor, a carriage slidably supported on the guides, sheet gripping clamps supported on the carriage, reference stops for the longitudinal and transverse positioning of the sheet relative to the conveyor feed direction, jacks for moving the gripping clamps between a position in which they pick up the sheet on the support surface and a position in which they abut against the transverse reference stops, and drive means for the carriage.
Prophylaxis for iron deficiency anemia using ferrous sulfate among infants followed up at a primary healthcare unit in the municipality of Embu-SP (2003/2004).

CONTEXT AND OBJECTIVE Iron deficiency anemia is an important public health problem in Brazil. In the municipality of Embu, a population study in 1996 found anemia prevalence of 68.5% among children aged one to two years. From these data, prescription of prophylactic ferrous sulfate was instituted in 1998 for children under two years old followed up within the children's healthcare program. After five years of intervention, the prevalence of anemia and associated factors were investigated among children aged 12 to 18 months to whom guidance for prophylactic ferrous sulfate use had been given. DESIGN AND SETTING Cross-sectional study covering October 2003 to June 2004 at a primary healthcare unit in Embu. METHODS A randomized sample of children aged 12 to 18 months to whom guidance for prophylactic ferrous sulfate use had been given was obtained. Hemoglobin was measured in capillary blood, using HemoCue apparatus. Hemoglobin < 11 g/100 dl was taken to indicate anemia. RESULTS The sample comprised 118 children and anemia was found in 41.5%. There was no statistically significant association between anemia presence and the variables of sex, birth weight, neonatal intercurrences, chronic diseases, breastfeeding or iron supplementation use. There was a statistically significant association (p = 0.03) between anemia presence and per capita income, such that the higher the income was, the lower the prevalence of anemia was. CONCLUSION The prophylaxis program against iron deficiency anemia did not achieve the expected results. New strategies must be considered in the light of the magnitude of the problem.