Miracle-dz/UniFAR-FTUs huggingface dataset:
Characterization of lipid particles of the yeast, Saccharomyces cerevisiae

Lipid particles of the yeast, Saccharomyces cerevisiae, were isolated to high purity and their components were analysed. The hydrophobic core of this organelle consists of triacylglycerols and steryl esters, which are almost exclusively located to that compartment. Lipid particles are stabilized by a surface membrane consisting of phospholipids and proteins. Electron microscopy confirmed the purity of the preparations and the proposed structure deduced from biochemical experiments. Major proteins of lipid particles have molecular weights of 72, 52, 43 and 34 kDa, respectively. The 43 kDa protein reacts with an antiserum against human apolipoprotein AII. In lipid particles of the yeast mutant strain S. cerevisiae erg6, which is deficient in sterol Δ24‐methyltransferase, this protein is missing thereby identifying the protein and confirming our previous finding (Zinser et al., 1993) that sterol Δ24‐methylation is associated with lipid particles. A possible involvement of surface proteins of lipid particles in the interaction with other organelles is discussed with respect to sterol translocation in yeast.
A compact wideband frequency selective surface for gain enhancement of a wide-slot antenna

This paper presents gain enhancement of a slot antenna using a reflective frequency selective surface (FSS). A pentagon shaped slot and offset feed is chosen for the antenna to cover 3-6 GHz. The dual layer FSS with compact unit cell (λ0/10) exhibits transmission below -10dB and thus good reflection in the same frequency band and a linear variation of reflection phase with frequency. The proposed FSS when used as a substrate below the antenna enhances its gain in the broadside direction over the entire band. The antenna with FSS shows an enhancement in gain by 2-4dB with a peak gain of 9dB in 3-6 GHz. An equivalent circuit of the FSS is presented along with its response obtained from ADS simulator. A prototype of the design is fabricated and measured results are presented with simulation.
Incremental learning algorithm for face recognition using DCT

Face Recognition System developed in this research work is based on newly invented Incremental Support Vector Machines for face recognition in which DCT (Discrete Cosine Transform) is used for the purpose to reduce the dimensionality of face space. Low frequency DCT coefficients are used to generate local features. Selected feature vectors are then fed into ISVM to classify the input data as a face ID or not. Incremental Support Vector Machine is used to learn data incrementally from previous stored data and also to avoid large training time and memory consumption for face recognition. In this approach ORL (Olivetti Research Laboratory)[28] face database is used for performing experiments and the results has proved that not only the training time but also the updating time taken by Incremental SVM is very less. Using this technique an accurate face recognition system is developed and tested and the performance found is efficient. The biggest advantage of using the ISVM is that it not only decreases the training time and updating time but also improves the classification accuracy rate to 100%.
What Is the Metabolic Syndrome?: Prediabetes and Cardiovascular Risk

The metabolic syndrome has been referred to as a clustering of cardiovascular risk factors, including abdominal obesity, atherogenic dyslipidemia, increased blood pressure, insulin resistance, proinflammatory state, and a prothrombotic state. The metabolic syndrome has become one of the leading clinical issues discussed by physicians and the media, leading to increased public awareness to this potentially catastrophic multiplex risk factor for cardiovascular disease. With increasing prevalence in the United States, the metabolic syndrome has been equated to cigarette smoking as a contributing factor to premature cardiovascular heart disease and one of the underlying causes of type 2 diabetes. The identification and modification of the root causes, overweight/obesity, physical inactivity, and the closely associated condition, insulin resistance, needs to be one of the initial strategies that are addressed by the clinician.
Performance analysis of APSK modulation for DVB‐S2 transmission over nonlinear channels

For increased bandwidth efficiency and receiver performance, standards for satellite broadcasting systems are evolving by utilizing efficient transmission techniques. The second‐generation digital video broadcasting for satellites (DVB‐S2) adopts the amplitude phase shift keying (APSK) modulation for enhanced performance over nonlinear channels. In this paper, we derive error rate bounds for APSK modulated symbols and generalize the bounds to the case of distorted constellation, which occurs when the maximum transmission amplitude is saturated by the soft‐limiter type channel. The derived bound is shown to significantly improve the previously known result, to accurately predict both the symbol error rate and bit error rate in the entire signal‐to‐noise ratio (SNR) region of interest. Using the derived formula, the optimal input power level for the soft‐limiter channel is determined, and the corresponding minimal error rates for 16‐ and 32‐APSK are quantified. The result is also interpreted in terms of optimal input back‐off (IBO) for nonlinear power amplifiers by evaluating the performance degradation as a function of IBO. Copyright © 2009 John Wiley & Sons, Ltd.
Degradation of humoral host defense by Candida albicans proteinase

The effect of an extracellular proteinase from the pathogenic yeast Candida albicans on the bactericidal and opsonizing activities of human serum was studied. The ability of human polymorphonuclear leukocytes to kill Staphylococcus aureus was greatly reduced when the bacteria were opsonized with human serum treated with the proteinase. The reduction in the opsonizing activity of human serum was attributed to degradation of the Fc portion of immunoglobulin G by the action of C. albicans proteinase as determined by immunoprecipitation reaction. However, the Fab portion of immunoglobulin G was resistant to proteolysis by the proteinase. A clear reduction in the bactericidal activity of human serum against Escherichia coli was observed when the serum was treated with C. albicans proteinase. The reduction of serum bactericidal activity was attributed to the degradation of complement C3 by proteolysis by the proteinase as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, while C5 resisted the action of the proteinase. As determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, the proteinase also degrades endogenous proteinase inhibitors, such as alpha 2 macroglobulin and alpha 1 proteinase inhibitor, which are involved in regulating inflammation. These results suggest that destruction of a host's defense-oriented or regulatory proteins facilitates debilitation of the infected host.
Cortical thickness is not associated with current depression in a clinical treatment study

Reduced cortical thickness is a candidate biological marker of depression, although findings are inconsistent. This could reflect analytic heterogeneity, such as use of region‐wise cortical thickness based on the Freesurfer Desikan–Killiany (DK) atlas or surface‐based morphometry (SBM). The Freesurfer Destrieux (DS) atlas (more, smaller regions) has not been utilized in depression studies. This could also reflect differential gender and age effects.
Adoption of strategic networks: evidence from the Hong Kong clothing industry

Purpose – Recent management literature demonstrates a growing interest in strategic networking. The aim of this paper is to explore the adoption of strategic networks using Hong Kong clothing industry as the context because the influence of Asian cultures is under‐researched.Design/methodology/approach – Three key research questions about asset specificity, years of relationship, and size of the supplier base were developed from the literature. Qualitative data were collected from in‐depth interviews with senior executives at five large clothing companies in Hong Kong.Findings – The qualitative findings confirm that the specific asset investment, reciprocal or one‐way, has a positive impact on the development of strategic networking; that enterprises strive hard to maintain longer relationships with key supplier members; and that a small supplier base is widely adopted by the sample firms.Practical implications – The implications for managerial practice are that strong strategic networking is needed as tr.
Neural Efficiency in Expert Cognitive-Motor Performers During Affective Challenge

ABSTRACT Skilled individuals demonstrate a spatially localized or relatively lower response in brain activity characterized as neural efficiency when performing within their domain of expertise. Elite athletes are experts in their chosen sport and thus must be not only adept in the motor domain but must be resilient to performing under the stress of high-level competition. Such stability of performance suggests this population processes emotion and mental stress in an adaptive and efficient manner. This study sought to determine if athletes with a history of successful performance under circumstances of mental stress demonstrate neural efficiency during affective challenges compared to age-matched controls. Using functional magnetic resonance imaging, the blood-oxygen level–dependent response was recorded during emotional challenge induced by sport-specific and general unpleasant images. The athletes demonstrated neural efficiency in brain regions critical to emotion regulation (prefrontal cortex) and affect (insula) independently of their domain of expertise, suggesting adaptive processing of negative events and less emotional reactivity to unpleasant stimuli.
Using Signifiers for Data Integration in Rail Automation

In Rail Automation, planning future projects requires the integration of business-critical data from heterogeneous data sources. As a consequence, data quality of integrated data is crucial for the optimal utilization of the production capacity. Unfortunately, current integration approaches mostly neglect uncertainties and inconsistencies in the integration process in terms of railway specific data. To tackle these restrictions, we propose a semi-automatic process for data import, where the user resolves ambiguous data classifications. The task of finding the correct data warehouse classification of source values in a proprietary, often semi-structured format is supported by the notion of a signifier, which is a natural extension of composite primary keys. In a case study from the domain of asset management in Rail Automation we evaluate that this approach facilitates high-quality data integration while minimizing user interaction.
An Analysis of Company Profile Translation in Henan Province from Skopos Theory

Company profile is the window of enterprises to propagandize their spirits and cultures, and enterprise profile translation is the guidance of broadening companies' channels to the international market, so the quality of it is very important for enterprise's development. This thesis aims to analyze the company profile translation of Henan province from skopos theory. First, it analyzes the mistakes of company profile translation and then discuss the factors, and at last it gives the corresponding practical translation strategies. The author expects this thesis could offer certain reference and theoretical support to the enterprise website translation of Henan province and improve the quality of corporate profile translation.
Licensing-in fosters rapid invention! the effect of the grant-back clause and technological unfamiliarity

Drawing on contractual economics and innovation management, licensing‐in is hypothesized to accelerate licensees' invention process. Studying a matched dataset of licensees and non‐licensees, licensees are shown to be faster at inventing, but the effect is negated if the license includes a grant‐back clause, shifting incentives from licensee to licensor. Also, the effect is significantly reduced if the licensee is unfamiliar with the licensed technology. The effect of the grant‐back clause is offset if the licensee is unfamiliar with the licensed technology, suggesting that the licensee retains the incentives to invent under these circumstances. Copyright © 2012 John Wiley & Sons, Ltd.
Lung Volumes, Mechanics, and Oxygenation during Spontaneous Positive‐Pressure Ventilation: the Advantage of CPAP Over EPAP

To determine if continuous positive airway pressure (CPAP) or expiratory positive airway pressure (EPAP) is superior for achieving or maintaining effective lung volume in spontaneously breathing critically in patients in acute respiratory failure, the authors measured functional residual capacity (FRC), airway and esophageal pressures, and arterial oxygen tensions when CPAP and EPAP were 5 and 10 cm H2O. Arterial oxygenation, FRC, and transpulmonary pressure at end-expiration were greatest when CPAP was 10 cm H2O. Lung compliance did not change. The authors conclude that CPAP at 10 cm H2O is the more effective technique, either because it allows relaxation of chest wall musculature on expiration, or because EPAP at 10 cm H2O increases chestwall muscle tone.
A Comparison of Ballistic Resistance Testing Techniques in the Department of Defense

Ballistic resistance testing is conducted in the Department of Defense (DoD) to estimate the probability that a projectile will perforate the armor of a system under test. Ballistic resistance testing routinely employs sensitivity experiment techniques where sequential test designs are used to estimate a particular quantile of the probability of perforation. Statistical procedures used to estimate the ballistic resistance of armor in the DoD have remained relatively unchanged for decades. In the current fiscal atmosphere of sequestration and budget deficits, efficiency is critical for test and evaluation. In this paper, we review and compare sequential methods, estimators, and stopping criteria used in the DoD to those found in literature. Using Monte Carlo simulation, we find that the three-phase optimal design, a probit model, and a break separation stopping criteria are most accurate and efficient at estimating V50, while the three-phase optimal design or Robbins-Monroe-Joseph method should be used to estimate V10.
Post-traumatic stress disorder: the role of trauma, pre-existing psychiatric disorders, and gender.

BACKGROUND The study is aimed at investigating the influence of trauma type, pre-existing psychiatric disorders with an onset before trauma, and gender on post-traumatic stress disorder (PTSD). METHODS Traumas, PTSD and psychiatric disorders were assessed in a representative sample of 4075 adults aged 18-64 years using the Composite International Diagnostic Interview. Pre-existing DSM-IV diagnoses of anxiety disorders, depressive disorders, somatoform disorders, alcohol abuse and dependence, nicotine dependence, gender, and the type of trauma were analysed with logistic regressions to estimate the influence of these factors on the risk for developing PTSD. RESULTS The lifetime prevalence of exposure to any trauma did not vary by gender. The conditional probability of PTSD after exposure to trauma was higher in women (11.1% SE = 1.58) than men (2.9% SE = 0.83). Univariate analyses showed that pre-existing anxiety disorders, somatoform disorders and depressive disorders significantly increase the risk of PTSD. Multivariate analyses revealed that specific types of trauma, especially rape and sexual abuse, pre-existing anxiety disorders and somatoform disorders are predictors of an increased risk of PTSD, while gender and depressive disorder were not found to be independent risk factors. CONCLUSION Women do not have a higher vulnerability for PTSD in general. However, especially sexually motivated violence and pre-existing anxiety disorders are the main reasons for higher prevalences of PTSD in women.
Service excellence models: a critical discussion and comparison

Purpose – As customer expectations expand and as product offerings hardly differ from each other, service excellence has gained in importance as a means of enhancing customer loyalty. The aim of this paper is to focus on expanding and extending what companies can do to achieve service excellence by comparing and evaluating three popular approaches to excellence.Design/methodology/approach – The authors compare three of the most commonly used excellence models, Johnston's conceptualisation of service excellence, the EFQM Model as a representative of national quality award models and the Kano model, and their respective applicability and specific perspective on service excellence. The evaluation is based on theoretical arguments, criteria and on a qualitative expert study.Findings – Combining the selected models provides a comprehensive approach to service excellence. Since all models are compatible and complementary with each other, the analysis provides an enhanced understanding of service excellence and .
Curve Stylization by Example using Histograms of Curvature

We present an approach for transferring the style of an exemplar curve to a target curve by analyzing and matching their distribution of curvatures at multiple scales. The user inputs two curves, an exemplar curve possessing a desired style and a guide curve determining the overall path of the output curve. We hypothesize that curvature is one of the fundamental features describing the style and use statistical analysis of the curvatures to transfer elements of the style to the guide curve. Histograms of curvatures of both curves are matched progressively by an iterative re-weighting scheme that minimizes an energy function balancing closeness of the curvature distributions and distance from the guide curve to the output curve. Our algorithm is able to match histograms well and produces interesting outputs in the single and multi-scale approach. Our results show that curves of similar style have similarly matching histograms at multiple scales, which leads to the transfer of elements of the style.
Peritoneal Catheter Removal for Severe Peritonitis: Landscape after a Lost Battle

155 For a patient undergoing chronic peritoneal dialysis (PD), catheter removal during the course of a severe peritonitis represents both a serious drawback and an essential resource in the battle against microbial infection. This measure is oriented to prevent the two major consequences of uncontrolled peritonitis, namely death and irreversible injury to the peritoneal membrane, the latter precluding future continuation of PD therapy. The indications for catheter removal during PD-related peritonitis remain partly empiric and must be individualized, but there is a general consensus that certain etiologic agents (fungi, multiple enteric bacteria) or clinical circumstances (simultaneous catheter tunnel infection, multi-relapsing infection, refractoriness to effective antibiotic therapy) demand a timely implementation of this procedure in a majority of cases to keep with the above mentioned objectives (1). Moreover, catheter removal is frequently a necessary step in the management of peritonitis caused by Staphylococcus aureus (2), gramnegative bacteria (3–6), and Mycobacterium tuberculosis (7). Catheter removal for peritonitis renders fair to good results when indicated for reasons other than the clinical aggressiveness of the infection, as in uncomplicated relapsing or catheter-dependent peritonitis. These settings allow a chance to induce clinical remission of the infection with antibiotics, permitting removal or even one-step catheter exchange (8) in the absence of peritoneal inflammation. On the contrary, catheter removal may be less consistent at the time in improving the outcome of severe peritonitis. First, the etiologic agent and the aggressiveness of the clinical presentation are essential predictors of peritonitis-related mortality and, as already mentioned, catheter removal is strongly linked to both factors (1). Thus, even assuming that this therapeutic maneuver may be lifesaving, it is not surprising that severe peritonitis complicated by catheter removal is usually associated with significantly higher mortality rates (6,9–11) than those reported for PD-related peritonitis overall (5,10,12,13). Overwhelming infection is an expected cause of demise in this context, but it is also worth emphasizing the high incidence of lethal cardiovascular events during the period following catheter removal for severe peritonitis, af ter temporary or PERITONEAL CATHETER REMOVAL FOR SEVERE PERITONITIS: LANDSCAPE AFTER A LOST BATTLE
Differential proteomic analysis of proteins induced by glucocorticoids in cultured murine podocytes.

BACKGROUND The glomerular podocyte is the kidney cell most affected during the development of nephrotic syndrome, and mutations in podocyte proteins are responsible for a variety of inherited forms of nephrotic syndrome. Although glucocorticoids are a primary treatment for nephrotic syndrome, neither their target cell nor mechanism of action are known. In order to describe the proteome of the podocyte, and to identify podocyte proteins whose expression is altered by glucocorticoids, we performed a differential proteomic analysis of control and dexamethasone-treated cultured murine podocytes. METHODS Podocyte proteins were separated by two-dimensional-polyacrylamide gel electrophoresis (PAGE) and identified by matrix-assisted laser desorption time-of-flight (MALDI-TOF) mass spectrometry and peptide fingerprinting. Comparisons of stained two-dimensional-PAGE separations were used to identify proteins whose expression was altered by treatment with the glucocorticoid dexamethasone, and these results were confirmed by quantitative Western blotting. RESULTS A total of 106 protein spots yielded MALDI-TOF results, and 92 were identified by protein fingerprinting. Of the 88 unique proteins and four protein isoforms identified, six proteins were found whose expression was altered by dexamethasone. The proteome of cultured murine podocytes is particularly rich in actin cytoskeletal proteins and proteins involved in responses to cellular stress. The change in expression of three proteins [ciliary neurotrophic factor (CNTF), alphaB-crystallin, and heat shock protein 27 (hsp27)] was confirmed by quantitative Western blotting. CONCLUSION Three proteins with known roles in protecting cells from injury were up-regulated by dexamethasone, demonstrating that glucocorticoids exert a direct effect on cultured podocytes resulting in changes in the expression of proteins with potential relevance to the therapeutic action of glucocorticoids in diseases such as nephrotic syndrome.