Miracle-dz/UniFAR-FTUs huggingface dataset:
Continuous Renal Replacement Therapy Applications on Extracorporeal Membrane Oxygenation Circuit

Background and Aims: Continuous venovenous hemofiltration or hemodiafiltration is used frequently in pediatric patients, but experience of continuous renal replacement therapy (CRRT) application on extracorporeal membrane oxygenation (ECMO) circuit is still limited. Among several methods used for applying CRRT on ECMO patients, we aim to share our experience on inclusion of a CRRT device in the ECMO circuit which we believe is easier and safer to apply. Materials and Methods: The data were collected on demographics, outcomes, and details of the treatment of ECMO patients who had CRRT. During the study period of 3 years, venous cannula of ECMO circuit before pump was used for CRRT access for both the filter inlet and outlet of CRRT machine to minimize the thromboembolic complications. The common indication for CRRT was fluid overload. Results: CRRT was used in 3.68% of a total number of patients admitted and 43% of patients on ECMO. The patients have undergone renal replacement therapy for periods of time ranging between 24 h and 25 days (260 h mean). The survival rate of this group of patients with multiorgan failure was 33%. Renal recovery occurred in all of the survivors. Complications such as electrolyte imbalance, hypothermia, and bradykinin syndrome were easily managed. Conclusions: Adding a CRRT device on ECMO circuit is a safe and effective technique. The major advantages of this technique are easy to access, applying CRRT without extra anticoagulation process, preventing potential hemodynamic disturbances, and increased clearance of solutes and fluid overload using larger hemofilter.
ATP-sensitive potassium channels--neonatal diabetes mellitus and beyond.

The revolution in molecular biology has led to widespread appreciation of a principle first described by the British physician A.E. Garrod approximately 100 years ago — that “inborn errors of metabolism” teach us much about human biology in health and disease. Neonatal diabetes mellitus is a prime example of this principle. Neonatal diabetes mellitus is rare, with a reported incidence of 1 per 500,000 newborns and an estimated incidence of 1 per 100,000 newborns (Hattersley A: personal communication). Most newborns with neonatal diabetes mellitus are born with intrauterine growth restriction (IUGR). The degree of IUGR is proportional to the degree .
Research on symmetric key-based mobile payment protocol security

This paper presents a payment model in which the mobile businessman is seen as trusted third party. Then we propose a new symmetric key-based mobile payment protocol and introduce both according key agreement protocol and payment protocol. In key agreement protocol, we introduce a Hash function with key based on RPC to guarantee payment authorization security. The payment protocol achieves security properties of payment anonymity, transaction privacy, incontestability and so on.
Psychosocial Determinants of Mammography Follow-up after Receipt of Abnormal Mammography Results in Medically Underserved Women

This article targets the relationship between psychosocial determinants and abnormal screening mammography follow-up in a medically underserved population. Health belief scales were modified to refer to diagnostic follow-up versus annual screening. A retrospective cohort study design was used. Statistical analyses were performed examining relationships among sociodemographic factors, psychosocial determinants, and abnormal mammography follow-up. Women with lower mean internal health locus of control scores (3.14) were two times more likely than women with higher mean internal health locus of control scores (3.98) to have inadequate follow-up (OR=2.53, 95% CI=1.12–5.36). Women with less than a high school education had lower cancer fatalism scores than women who had completed high school (47.5 vs. 55.2, p-value=.02) and lower mean external health locus of control scores (3.0 vs. 5.3) (p-value<.01). These constructs have implications for understanding mammography follow-up among minority and medically underserved women. Further comprehensive study of these concepts is warranted.
Adherence to World Cancer Research Fund/American Institute for Cancer Research Lifestyle Recommendations Reduces Prostate Cancer Aggressiveness Among African and Caucasian Americans

The effect of adherence to the World Cancer Research Fund (WCRF) lifestyle recommendations on cancer aggressiveness is unknown. We examined associations between adherence to recommendations and risk of highly aggressive prostate cancer in research subjects enrolled in the North Carolina-Louisiana Prostate Cancer Project (PCaP). We examined associations between adherence to WCRF recommendations and risk of highly aggressive prostate cancer among 2212 newly diagnosed African Americans (AA) or Caucasian Americans (CA) aged 40–70 years in PCaP. Prostate cancer aggressiveness was based on Gleason scores, serum prostate-specific antigens, and TNM stage. Adherence to WCRF recommendations was based on point scores and odds ratios estimated. Results showed that adherence to recommendations was significantly and negatively associated with risk of a highly aggressive prostate cancer. Each additional point in the total adherence score corresponded to a 13% risk reduction. Total adherence score <4 predicted increased risk in both AA (OR = 1.36; 95% CI = 1.01–1.85) and CA (OR = 1.41; 95% CI = 1.01–1.98). Consumption of <500 g red meat per week or ≤125 total kcal/100 g solid food per day is a statistically significant protective factor in the overall cohort. Recommendations aimed at preventing all cancers also may reduce risk of highly aggressive prostate cancer.
Looking beyond knowledge sharing: an integrative approach to knowledge management culture

Purpose This study aims to identify the main knowledge processes associated with organizational knowledge culture. A diverse range of knowledge processes have been referred to in the extant literature, but little agreement exists on which knowledge processes are critical and should be supported by organizational culture. Design/methodology/approach Using a systematic literature review methodology, this study examined the primary literature – peer-reviewed and scholarly articles published in the top seven knowledge management and intellectual capital (KM/IC)-related journals. Findings The core knowledge processes have been identified – knowledge sharing, knowledge creation and knowledge implementation. The paper suggests that a strategy for implementing successful organizational KM initiatives requires precise understanding and effective management of the core knowledge infrastructures and processes. Although technology infrastructure is an important aspect of any KM initiative, the integration of knowledge into management decisions and practices relies on the extent to which the organizational culture supports or hinders knowledge processes. Research limitations/implications The focus of the study was on the articles published in the top seven KM/IC journals; important contributions in relevant publications in other KM journals, conference papers, books and professional reports may have been excluded. Practical implications Practitioners will benefit from a better understanding of knowledge processes involved in KM initiatives and investments. From a managerial perspective, the study offers an overview of the state of organizational knowledge culture research and suggests that for KM initiatives to be successful, the organization requires an integrated culture that is concerned with knowledge processes as a set of inextricably inter-related processes. Originality/value For the first time, a comprehensive list of diverse terms used in describing knowledge processes has been identified. The findings remove the conceptual ambiguity resulting from the inconsistent use of different terms for the same knowledge process by identifying the three major and overarching knowledge processes. Moreover, this study points to the need to attend to the inextricably interrelated nature of these three knowledge processes. Finally, this is the first time that a study provides evidence that shows the KM studies appear to be biased towards Knowledge sharing.
Controlling Risks of Pathogen Transmission by Flies on Organic Pig Farms

Fly prevention and control on animal production units is necessary to prevent the transmission of pathogens that could affect animal and human health and the maintenance of good hygiene. Organic farmers are often hesitant to apply insecticides for this purpose because of their farming philosophy. Organic production systems are relatively open as pigs generally have access to the outdoors. Here, we investigate the need for fly control and analyse various possibilities that organic farmers have to reduce the number of flies on their farms. We conclude that although biological control looks promising, more research should be done concerning its side effects. Currently, optimal monitoring and prevention seem to offer the best solution.
Quantitative salivary gland scintigraphy in the diagnosis of parenchymal damage after treatment with radioiodine

SummaryThis study was undertaken to quantify salivary gland parenchymal damage after radioiodine treatment with a standard protective regimen of ascorbic acid. Altogether, 106 patients underwent quantitative salivary gland scintigraphy with 99Tcm-pertechnetate prior to and 3 months after radioiodine therapy. Parenchymal function was quantified by calculating 99Tcm-pertechnetate uptake 13 min post-injection. Patients received 131I doses ranging from 400 MBq to 24 GBq (cumulative). Among the patients who received large doses of 131I, severe parenchymal destruction could be visually analysed as well as quantitatively evaluated. In contrast, after low-dose radioiodine treatment, mild parenchymal impairment was demonstrated by quantitative evaluation only. In conclusion, standardized quantitative salivary gland scintigraphy is essential for the reliable detection of mild parenchymal malfunction. Despite the standard protection regimen using ascorbic acid as a sialogogue, radioiodine therapy induces loss of salivary gland parenchymal function even with low doses of 131I.
Phototropism: Mechanism and Outcomes

Plants have evolved a wide variety of responses that allow them to adapt to the variable environmental conditions in which they find themselves growing. One such response is the phototropic response - the bending of a plant organ toward (stems and leaves) or away from (roots) a directional blue light source. Phototropism is one of several photoresponses of plants that afford mechanisms to alter their growth and development to changes in light intensity, quality and direction. Over recent decades much has been learned about the genetic, molecular and cell biological components involved in sensing and responding to phototropic stimuli. Many of these advances have been made through the utilization of Arabidopsis as a model for phototropic studies. Here we discuss such advances, as well as studies in other plant species where appropriate to the discussion of work in Arabidopsis.
An energy efficient ring routing protocol for wireless sensor network

WSN is a wireless network consists of tiny sensor nodes which are scattered autonomously and capable of sensing physical or environmental conditions the main concern of WSN is energy efficiency. Because the nodes near the sink drain their energy more rapidly than the other nodes in the network. The reason behind this is the data requests are transferred towards the node near to the sink. To triumph over this problem there are numerous approaches are already implemented which aims to reduce the overload of advertising the position of sink node to the network. The reason behind this is the data requests are transferred towards the node near to the sink. To triumph over this problem there are numerous approaches are already implemented which concentrates on reducing the overload of announcement of position of sink to network, by implementing a hierarchy of nodes which assigns different roles on the sensor nodes such as ring nodes and sink node. There are some existing routing protocols which aims to enhance energy efficiency of network but still they have some drawbacks like nodes become hotspots, Packets losses, Delays and energy consumption. So to enhance the routing in efficient manner which will reduce the energy consumption by WSN nodes, introduced Ring Routing protocol is a innovative, scattered and energy-proficient mobile sink routing protocol which is intended for time sensitive application, which aim to lessen these overheads while preserving compensation of mobile sinks. The Ring Routing is hierarchical mobile sink protocol which is based on virtual ring composition which can be easily reconfigurable as well as accessible.
Using relative head and hand-target features to predict intention in 3D moving-target selection

Selection of moving targets is a common, yet complex task in human-computer interaction (HCI) and virtual reality (VR). Predicting user intention may be beneficial to address the challenges inherent in interaction techniques for moving-target selection. This article extends previous models by integrating relative head-target and hand-target features to predict intended moving targets. The features are calculated in a time window ending at roughly two-thirds of the total target selection time and evaluated using decision trees. With two targets, this model is able to predict user choice with up to ~ 72% accuracy on general moving-target selection tasks and up to ~ 78% by also including task-related target properties.
Follow-up and surveillance of the patient with lung cancer after curative-intent therapy: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.

BACKGROUND These guidelines are an update of the evidence-based recommendations for follow-up and surveillance of patients after curative-intent therapy for lung cancer. Particular updates pertain to whether imaging studies, health-related quality-of-life (HRQOL) measures, tumor markers, and bronchoscopy improve outcomes after curative-intent therapy. METHODS Meta-analysis of Observational Studies in Epidemiology guidelines were followed for this systematic review, including published studies on posttreatment outcomes in patients who received curative-intent therapy since the previous American College of Chest Physicians subject review. Four population, intervention, comparison, and outcome questions were formulated to guide the review. The MEDLINE and CINAHL databases were searched from June 1, 2005, to July 8, 2011, to ensure overlap with the search strategies used previously. RESULTS A total of 3,412 citations from MEDLINE and 431 from CINAHL were identified. Only 303 were relevant. Seventy-six of the 303 articles were deemed eligible on the basis of predefined inclusion criteria after full-text review, but only 34 provided data pertaining directly to the subject of the questions formulated to guide this review. In patients undergoing curative-intent surgical resection of non-small cell lung cancer, chest CT imaging performed at designated time intervals after resection is suggested for detecting recurrence. It is recommended that treating physicians who are able to incorporate the patient's clinical findings into decision-making processes be included in follow-up and surveillance strategies. The use of validated HRQOL instruments at baseline and during follow-up is recommended. Biomarker testing during surveillance outside clinical trials is not suggested. Surveillance bronchoscopy is suggested for patients with early central airway squamous cell carcinoma treated by curative-intent photodynamic therapy and for patients with intraluminal bronchial carcinoid tumor who have undergone curative-intent bronchoscopic treatment with Nd:YAG laser or electrocautery. CONCLUSIONS There is a paucity of well-designed prospective studies specifically targeting follow-up and surveillance modalities aimed at improving survival or QOL after curative-intent therapy. Additional research is warranted to clarify which curative-intent treatment modalities affect HRQOL the most and to identify patients who are at the most risk for recurrence or impaired QOL after treatment. Further evidence is needed to determine how the frequency and duration of surveillance programs that include imaging studies, QOL measurements, tumor markers, or bronchoscopy affect patient morbidity, survival, HRQOL, and health-care costs.
Detection scheme for human body using UWB radio in NLOS environments

UWB (Ultra Wideband) radar has higher resolution ranging capability by using very short pulses. In this paper, a human body detection technique is examined when the human is blocked by obstacles. Channel responses of transmission path are measured in the anechoic chamber. A path detection scheme is adopted to find the reflected paths from the human body. The amplitude and delay time of the paths can be estimated by using proposed path detection scheme. The human body and wall can be distinguished by difference of the power and delay time of paths estimated from the channel responses that are measured in multiple times. The proposed technique is effective to find the human even when power of the reflection signal from the human body is weaker.
Density of Demodex folliculorum in rosacea: a case‐control study using standardized skin‐surface biopsy

A standardized skin‐surface biopsy (1 cm2) of the cheek was performed in 49 patients with rosacea [13 with erythematotelangiectatic rosacea (ETR). three with squamous rosacea (SR), 33 with papulopustular rosacea (PPR)], and 45 controls.
Nanocalcium sulfate and collagen biomaterials: Effects on osteoblastic cells

Introduction: Guided bone regeneration (GBR) using the principle of guided tissue regeneration (GTR) has been widely demonstrated to be a useful technique for enhancing bone healing in a variety of osseous defects including those in periodontal and peri-implant regions. Placement of a biocompatible membrane to guide desirable cells such as osteoblasts to the appropriate site is a critical step in GBR. Optimization of the process includes the prevention of collapse of the membrane with bone grafting materials that also enhance the growth and differentiation of osteoblastic cells at the desired site. The purpose of this in vitro study was to assess the ability of a nano-sized calcium sulfate product (nCS) to enhance the growth and differentiation of human osteoblastic cells on biocompatible collagen materials commonly used in GBR. Materials and methods: Human osteoblastic cells were cultured under standard in vitro conditions on collagen materials (HeliPLUG® Collagen, RCM6TM, or BioGide®) with or without a coating of nCS. The growth activity of the cells was evaluated with the MTT assay and differentiation with measurements of alkaline phosphatase and in some cases with an Alizarin Red mineralization assay. Results and conclusion: nCS increased the activity of cells incubated on pieces of HeliPLUG® Collagen and RCM6TM with nonsignificant effects on the BioGide® response. Alkaline phosphatase activity was increased by the presence of nCS with all three collagen products tested. Mineralization was assessed with only the HeliPLUG® Collagen material and marked significant effects of the nCS coating was observed. These data suggest that the effectiveness of the collagen biomaterials commonly used clinically can be increased with respect to GBR by the concurrent use of nCS. Correspondence to: Rosemary Dziak, PhD, Professor, Department of Oral Biology, University at Buffalo School of Dental Medicine, 318 Foster Hall, South Campus, Main Street, Buffalo, NY 14206, USA, Tel: 1.716. 829.3827, E-mail: rdziak@buffalo.edu
The SDM 3 Circle Model: A Literature Synthesis and Adaptation for Shared Decision Making in the Hospital

&NA; Patient engagement through shared decision‐making (SDM) is increasingly seen as a key component for patient safety, patient satisfaction, and quality of care. Current SDM models do not adequately account for medical and environmental contexts, which may influence medical decisions in the hospital. We identified leading SDM models and reviews to inductively construct a novel SDM model appropriate for the inpatient setting. A team of medicine and pediatric hospitalists reviewed the literature to integrate core SDM concepts and processes and iteratively constructed a synthesized draft model. We then solicited broad SDM expert feedback on the draft model for validation and further refinement. The SDM 3 Circle Model identifies 3 core categories of variables that dynamically interact within an “environmental frame. ” The resulting Venn diagram includes overlapping circles for (1) patient/family, (2) provider/team, and (3) medical context. The environmental frame includes all external, contextual factors that may influence any of the 3 circles. Existing multistep SDM process models were then rearticulated and contextualized to illustrate how a shared decision might be made. The SDM 3 Circle Model accounts for important environmental and contextual characteristics that vary across settings. The visual emphasis generated by each “circle” and by the environmental frame direct attention to often overlooked interactive forces and has the potential to more precisely define, promote, and improve SDM. This model provides a framework to develop interventions to improve quality and patient safety through SDM and patient engagement for hospitalists.
Sedimentary organic matter preservation : A test for selective degradation under oxic conditions

The authors report here a test of the hypothesis that the extent of organic matter preservation in continental margin sediments is controlled by the average period accumulating particles reside in oxic porewater immediately beneath the water/sediment interface. Oxygen penetration depths, organic element compositions, and mineral surface areas were determined for 16 sediment cores collected along an offshore transect across the Washington continental shelf, slope, and adjacent Cascadia Basin. Individual amino acid, sugar, and pollen distributions were analyzed for a 11 to 12 cm horizon from each core, and {sup 14}C-based sediment accumulation rates and stable carbon isotope compositions were determined from depth profiles within a subset of six cores from representative sites. Sediment accumulation rates decreased, and dissolved O{sub 2} penetration depths increased offshore along the sampling transect. As a result, oxygen exposure times (OET) increased seaward from decades (mid-shelf and upper slope) to more than a thousand years (outer Cascadia Basin). Organic contents and compositions were essentially constant within individual sediment cores but varied consistently with location. In particular, organic carbon/surface area ratios decreased progressively offshore and with increasing OET. Three independent compositional parameters demonstrated that the remnant organic matter in farther offshore sediments is more degraded. Both concentrationmore » and compositional patterns indicated that sedimentary organic matter exhibits a distinct and reproducible oxic effect. OET helps integrate and explain organic matter preservation in accumulating continental margin sediments and hence provides a useful tool for assessing transfer of organic matter from the biosphere to the geosphere. « less