Miracle-dz/UniFAR-FTUs huggingface dataset:
Risk analysis of maritime accidents along the main route of the Maritime Silk Road: a Bayesian network approach

ABSTRACT The safety of maritime transportation along the twenty-first century Maritime Silk Road (MSR) is important to ensure its development and sustainability. Maritime transportation poses risks of accidents that can cause the death or injury of crew members and damage to ships and the environment. This paper proposes a Bayesian network (BN) based risk analysis approach that is newly applied in the main route of the MSR to analyse its relevant maritime accidents. The risk data are manually collected from the reports of the accident that occurred along the MSR. Next, the risk factors are identified and the results from the modelling method can provide useful insights for accident prevention. Historical data collected from accident reports are used to estimate the prior probabilities of the identified risk factors influencing the occurrence of maritime accidents. The results show that the main influencing factors are the type and location of an accident and the type, speed, and age of the involved ship(s). In addition, scenario analysis is conducted to analyse the risks of different ships in various navigational environments. The findings can be used to analyse the probability of each possible maritime accident along MSR and to provide useful insights for shipowners’ accident prevention.
Object-Based Characterization and Semantic Labeling of Landslide and Rockfall phenomena using UAV photogrammetry

A variety of remote sensing tools have been extensively used in the past years for landslide detection and mapping purposes. In addition, detection and mapping of landslide and rockfall events using remote sensing products has been proved to be an effective approach to provide landslide inventories (Scaioni et al., 2014). However, most of the studies are lacking valuable semantic information about landslide elements and how they react with the surrounding environment; natural and man-made primitives. Late years, innovative close-range remote sensing technology such as Unmanned Aerial Vehicle (UAV) photogrammetry and Terrestrial Laser Scanning (TLS) are widely applied in the field of geoscience due to their efficiency in collecting data about terrain morphology rapidly. Their main advantage stands on the fact that conventional methods are mainly collecting point measurements such as compass measurements of bedding and fracture orientation only from areas that were accessible. Aerial platforms are capable to overcome technical issues such as potential occlusions and unfavorable incidence angles due to their ability to capture imagery from multiple positions and with different angles. Nowadays, UAVs tend to be more flexible and powerful tools for landslide and rockfall investigations compared with TLS due to their low-cost and ease of transportability in harsh environments but also with technology advancements such as maintaining of RTK positioning. An important factor of their usefulness is their capability to offer unprecedented spatial resolution over wide inaccessible areas, maintain a variability of different sensors (optical, laser, thermal, multispectral) and great ability to reach remote areas and acquire data as close as the user defines. UAVs applications are widely used in post-disaster situations for emergency support, in infrastructure monitoring, in natural resources management, in geohazard monitoring etc. (Corominas et al., 2016). The latter proves that UAV market has been rapidly growing over the last decade and in future more applications will be introduced in the public. Thus, rapidness and efficiency of SfM technology in landslide management provides numerous advantages such as creating landslide inventory maps providing 3D information of large areas.
Optimal placement and sizing of energy storage systems to improve the reliability of hybrid power distribution network with renewable energy sources

Abstract Concept of renewable hybrid energy systems have attracted many utilities and implemented by them too. With such energy systems, customers are not only supplied more economically but also more reliably. Moreover, optimal placements of energy storage systems (ESSs) increase the reliability of such hybrid renewable system up to a great extent. Therefore, this paper presents a new approach for optimal placement and sizing of energy storage systems (ESSs) in hybrid renewable radial distribution system to improve the reliability of such system without violating the system constraints. The cost of energy not supplied (CENS) associated with power service interruption and power shortage is also been considered in the objective function during placement of ESSs. Hence, the proposed optimal placement planning of ESSs is presented with an aim of minimizing the objective function includes cost of energy not supplied (CENS), investment cost and operational cost of ESSs, and power loss in distribution system. It is to be noted that the Particle swarm optimization (PSO) technique is adopted to minimize the objective function. The presented methodology is demonstrated by considering several case studies on 11 kV, 30 bus radial distribution system. Further, a rigorous sensitivity analysis is performed by limiting the number of applied ESSs and varying the maximum capacity of participating ESSs.
Parity and Risk of Low Birth Weight Infant in Full Term Pregnancy

Latar belakang: Berat badan lahir rendah meningkatkan morbiditas dan mortalitas pada bayi baru lahir. Hasil Riskesdas 2010 dan 2013 menunjukkan penurunan angka prevalensi berat badan lahir rendah dari 11,1% menjadi 10,2%. Tujuan penelitian ini adalah mengidentifikasi faktor risiko yang berkaitan dengan kejadian berat badan lahir rendah pada kehamilan cukup bulan. Metode: Penelitian potong lintang di dua rumah sakit di Jakarta dengan menggunakan data sekunder. Data rekam medik wanita yang melahirkan pada periode 1 Januari sampai 31 Desember 2011 dipilih secara purposif. Berat badan lahir rendah adalah berat badan kurang dari 2500g pada bayi baru lahir. Analisis data dilakukan dengan menggunakan regresi logistik. Hasil: Pada analisis ini didapatkan 2242 subyek yang memenuhi kriteria, dari 4191 subyek. Proporsi berat badan lahir rendah adalah 9,5%. Jika dibandingkan dengan primipara, wanita nullipara memiliki risiko melahirkan bayi dengan berat badan lahir rendah 46% lebih tinggi [adjusted odds ratio (ORa) = 1.46; P=0.030]. Selanjutnya, jika dibandingkan dengan bayi laki-laki, bayi perempuan memiliki risiko 42% lebih tinggi mengalami berat lahir rendah (ORa = 1.42; P=0.017) Kesimpulan: Bayi berat badan lahir rendah pada kehamilan cukup bulan lebih sering ditemukan pada wanita nullipara dan bayi perempuan. Kata kunci: paritas, jenis kelamin bayi, berat badan lahir rendahBackground: Low birth weight infants tend to increase the occurence of early infant mortality and morbidity. The survey in Indonesia suggested that the prevalence of low birth weight declined from 11.1% in 2010 to 10.2% in 2013. This study aims to identify the risk factors of low birth weight infant in full term pregnancy. Methods: This was a cross-sectional study using secondary data from two hospitals in Jakarta. The data was obtained from medical records of pregnant women who gave birth during the period of January 1 to December 31, 2011. Multivariat logistic regression model with stepwise method was used to analyze the risks of low birth weight. Results: The sample size in this study was 4191 subjects. Out of them 2242 subjects met the inclusion criteria. The proportion of low birth weight was 9.5%. Compared with primipara, nullipara had 46 % increased risk to have LBW infant (ORa = 1.46; P=0.030), meanwhile primipara and nullipara did not have significant difference for having LBW infants (ORa = 0.90; P=0.614). In term of sex of infants, female infant had 42% higher risk of having LBW infant compared with male infant (ORa = 1.42; P=0.017). Conclusion : Low birth weight infants in full term pregnancies are more common in nullipara and most of the LBW infants are female
DTLShps: SDN-Based DTLS Handshake Protocol Simplification for IoT

Datagram transport layer security (DTLS) protocol is widely used in Internet of Things (IoT) for providing security services. The computational overhead makes it hard to implement DTLS on resource-constrained IoT devices. The two significant costly computations in the DTLS handshake are the Diffie–Hellman (DH) key exchange and the certificate verification. A simplified handshake protocol of DTLS (DTLShps) is proposed to reduce the computational overhead of the IoT devices for a general scenario of end-to-end communications based on software-defined networking (SDN). First, a controller is utilized to generate a symmetric key dynamically, then encrypt and distribute this key to two communicating IoT devices. Second, the certificate verification is shifted from the IoT device to the more powerful controller. Third, the controller replaces the DTLS server to make a cookie exchange with the DTLS client. Furthermore, the BAN logic and the tool Scyther are used to validate the security of our scheme. The performance evaluation shows that not only the computational overhead and the energy consumption in the IoT devices are effectively decreased but also the overall duration of the whole handshake is reduced.
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats

ABSTRACT — β, β-dimethylacrylalkannin is a major active chemical component extracted from Lithospermum erythrorhizon, a traditional Chinese medicine that exhibits strong antimicrobial, anti-cancer and anti-inflammatory activities. However, its potential toxicity has not been rigorously studied. To confirm its safety, the oral toxicity of β, β-dimethylacrylalkannin was evaluated in vivo. An acute oral toxicity study in mice demonstrated that β, β-dimethylacrylalkannin was practically nontoxic based on its high median lethal dose (LD50 > 10 g/kg). No deaths or abnormal responses were observed in the acute toxicity test using Wistar rats, suggesting that the maximum tolerated dose of β, β-dimethylacrylalkannin was greater than 10 g/kg. Chronic toxicity studies also revealed an absence of mortality and clinical symptoms, and no treatment-related adverse effects were detected by hematology, blood biochemistry and urinalysis examinations in all rats treated with 10-160 mg/kg/day β, β-dimethylacrylalkannin during a 6-month period. Increases in the relative organ weight of the lungs of females and the liver of males were observed at 160 mg/kg. Histopathological analyses revealed brown pigmentation in renal tubular epithelial cells at the middle and high doses (40-160 mg/kg/day). The no-observed-adverse-effect level (NOAEL) of β, β-dimethylacrylalkannin is 10 mg/kg/day. These results suggest that β, β-dimethylacrylalkannin is potentially safe for further development as a therapeutic agent in humans.
Intracranial-EEG evidence for medial temporal pole driving amygdala activity induced by multi-modal emotional stimuli

The temporal pole (TP) is an associative cortical region required for complex cognitive functions such as social and emotional cognition. However, functional mapping of the TP with functional magnetic resonance imaging is technically challenging and thus understanding of its interaction with other key emotional circuitry, such as the amygdala, remain elusive. We exploited the unique advantages of stereo-electroencephalography (SEEG) to assess the responses of the TP and the amygdala during the perception of emotionally salient stimuli of pictures, music and movies. These stimuli consistently elicited high gamma responses (70-140 Hz) in both the TP and the amygdala, accompanied by functional connectivity in the low frequency range (2-12 Hz). Computational analyses suggested the TP driving this effect in the theta-alpha frequency range and which was modulated by the emotional salience of the stimuli. Of note, cross-frequency analysis indicated the phase of theta-alpha oscillations in the TP modulated the amplitude of high gamma activity in the amygdala. These results were reproducible with three types of stimuli including naturalistic stimuli suggesting a hierarchical influence of the TP over the amygdala in non-threatening stimuli.
Diversidade e prevalência das mutações de resistência genotípica aos antirretrovirais entre crianças infectadas pelo HIV-1

Objetivo: avaliar a genotipagem e subtipagem em crianças experimentadas e virgens de tratamento, assim como perfis de resistência a medicamentos através da genotipagem nessas crianças. Métodos: estudo retrospectivo de crianças HIV positivas virgens de tratamento e HIV positivas que não responderam ao tratamento pela terapia antirretroviral altamente ativa (HAART), acompanhadas na Santa Casa de São Paulo (SP). A genotipagem foi realizada com produtos purificados de reação em cadeia da polimerase (PCR) de RNA retrotranscrito, utilizando-se o kit comercial Viroseq HIV-1 Genotyping System 2.0 ou a técnica de nested PCR in-house. O sequenciamento foi realizado com equipamento automático (ABI 3100). As mutações de resistência antirretroviral (ARV) foram analisadas no Stanford HIV Drug Resistance Database e a subtipagem realizada no U.S. National Center for Biotechnology Information (NCBI), utilizando-se o programa de análises SimPlot, juntamente com a análise filogenética. Resultados: não foi detectada nenhuma mutação de resistência primária ARV nas 24 crianças virgens de tratamento, embora tenham ocorrido mutações que podem contribuir para a resistência aos inibidores da transcriptase reversa análogos de nucleosídeos (ITRN) (12,5%) e aos inibidores da protease (IP) (95,8%). Para as 23 crianças que não responderam à HAART, foram encontradas mutações de resistência ARV aos ITRN em 95,6% e aos inibidores da transcriptase reversa não-análogos de nucleosídeos (ITRNN) em 60,8%. Para os IP, foram observadas mutações de resistência ARV em 95,7%, 47,8% das quais apresentavam apenas polimorfismos. Nas análises de subtipagem, 78,3% das sequências agruparam-se no subtipo B do HIV-1, 4,3% no C, 13% no F e 4,4% em formas recombinantes. Conclusões: nossos resultados mostram baixas taxas de resistência primária em crianças virgens de tratamento e altas taxas de resistência em crianças que não responderam ao tratamento ARV, o que é compatível com o uso ARV nesses pacientes.
ANNs approach to identify water demand drivers for Saf-Saf river basin

This paper presents artificial neural network (ANN) techniques such as generalized regression neural networks (GRNNs), radial basis neural networks (RBFNNs) and multilayer perceptron neural networks (MLPNNs) for predicting quarterly water demand (QWD). The data set including total of 720 data records is divided into two subsets, training and testing. Various ANN models depending on the combination of antecedent values of water demand, temperature, rainfall and population are constructed and the best-fit input structure is examined. The performance of ANN models in training and testing phases are compared with the observed water demand values to select the best-fit forecasting model. For this purpose, some performance criteria such as root mean square error, coefficient of determination (R2) and accuracy factor (Af) are evaluated for different models (GRNN, RBFNN and MLPNN). The results indicated that MLPNN outperforms all other ANN techniques (GRNN and RBFNN) in the forecasting of QWD. Abbreviations: Af, accuracy factor; ANN, artificial neural networks; GRNN, general regression neural network; MLPNN, multilayer perceptron neural network; P, seasonal mean rainfall (in mm); Pop, population (in number); RBFNN, radial basis function neural network; RMSE, Root mean square error; R2, Coefficient of determination; T, seasonal mean temperature (in °C); QWD: quarterly water demand (measured by 106m3)
Assessment of Micro Nutritional Malnutrition in an Urban Area of Bangladesh among the Adult Population on the Basis of Individual Dietary Diversity Score (IDDS)

Background/objecives: Micro nutritional malnutrition is a global public health problem contributing directly and indirectly to morbidity and mortality of billions of peoples worldwide. Vitamin and mineral deficiencies are widespread, affecting one third of the global population. The general objective of the study was assessment of average Individual Dietary Diversity Score (IDDS) in selected adult urban population. Subjects and methods: In this study 300 subjects of which 150 male and 150 female were studied. Among 300 subjects 100 were hostel student, 100 were non hostel student and 100 were slum people with ranges were 18-30 years of age. The Study was conducted in an urban area of Dhaka. Pre-structured questionnaire was developed with relevant information’s. The food intake patterns of the subjects were recorded by 24 hours recall method and used nine food groups for IDDS information. IDDS was calculated according to Low IDDS ( 6 Food groups). Results: Our Results showed that 150 male out of 300 participants IDDS and FCS were 4.15 ± 0.88, 6-2, 9.88 ± 1.88, 15-5. On the other hand, among 150 female their IDDS and FCS were 4.28 ± 1.2, 7-2, 9.43 ± 2.38, 15-4. P value of IDDS and FCS were 0.064 and 0.069. Education was the highly significant (p<0.001) associated with Food Consumption Score (FCS) and sex was significant (p<0.03) with Food Consumption Score (FCS). Conclusion: Academic qualification of the family is associated with Individual Dietary Diversity Score (IDDS) and Food Consumption Score (FCS).
PHYSICAL FITNESS AGE OF MIDDLE-AGED AND ELDERLY MEN WITH CORONARY HEART DISEASE AND ITS CHANGES FOLLOWING AN EXERCISE PROGRAM

Biological age based on the assessment of various physiological factors measured in a resting state has been proposed as an appropriate index of aging. We have recently developed an equation for estimation of physical fitness age (PFA), which is composed of eight agerelated physical fitness variables. These include oxygen uptake corresponding to lactate threshold (Vo2@LT), maximal oxygen uptake (Vo2max), side step, grip strength, vertical jump, foot balance with eyes closed, trunk extension, and trunk flexion. In this study, the validity of PFA as a critical index of physical health and/or aging status was investigated from a longitudinal standpoint on the assumption that exercise habituation does contribute to health promotion. The subjects were 14 Japanese middle-aged and elderly men, aged 50 to 70 years, all of whom were patients with coronary heart disease(CHD). The subjects participated in a supervised exercise conditioning program for 90 to 120 min each session, 2 times weekly for 4 months. Analyses of the data indicated that the mean PFA of the subjects (66.0•}9.0 yr) after conditioning was significantly (P<0.05) lower than the mean PFA (72.8•}8.6 yr) obtained before conditioning. After the exercise program, significant increases were documented in Vo2@LT (17%), Vo2max (12%), side step (26%), trunk flexion (109%), trunk extension (7%), vertical jump (12%), and foot balance with eyes closed (31%). Therefore, we conclude that our exercise conditioning program may alter the overall physical fitness of patients with CHD, and that PFA could be a valid physical health and/or aging index. (Jpn. J. Phys. Fitness Sports Med. 1993, 42 :371•`379) key words : Physical fitness age, Health index, Coronary heart disease, Exercise program
Long Term Outcome of Gastric MALT Lymphoma Patients Treated with Anti-Helicobacter (Antibiotic and Proton-Pump Inhibitor) Regimens.

Background: Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach is often associated with Helicobacter pylori (Hp) infection and Hp eradication therapy is widely accepted as initial treatment. The aim of this study is to report the clinical characteristics and long term outcome in a large series of patients with gastric MALT lymphoma exclusively treated with Hp eradication therapy. Methods: 105 newly diagnosed gastric MALT lymphoma patients (54 men and 51 women) with median age of 64 years (range 20–94) referred to our institutions between June 1990 and November 2006 were eligible for the study. Staging was performed according to the Lugano staging system. All patients received anti-Hp eradication therapy as initial treatment with standard regimens combining antibiotics (usually Amoxicillin, Clarithromycin and/or Metronidazole) and proton-pump inhibitors (Omeprazole in most cases). Responses, evaluated with regular endoscopic biopsies every 3–6 months were graded according to the Wotherspoon’s histological score system. Results: 100 patients had stage I and 5 patients had stage IIE1 disease. Hp was positive in 83 patients (79.5%) and was eradicated in all positive patients but 19 patients required a second line antibiotic therapy. Symptoms disappeared or markedly diminished and endoscopic features improved in almost all patients after Hp eradication. Histological regression of the gastric lymphoma was achieved in 78 of 102 evaluable patients (76%, 95% C.I.; 67%–84%) with histological complete response (Wotherspoon’s score 0–2) in 66 and partial response (score 3) in 12 patients. Of the 78 patients who achieved a lymphoma regression, the histological remission was consistently confirmed at follow-up endoscopies in 28 patients (36%), while 33 (42%) had histological score fluctuations (from 0–4), sometimes with transient histological relapses followed by spontaneous histological remissions. Ten patients had a frank lymphoma relapse (2 with high-grade transformation) and 7 died in remission for other causes. At a median follow up time of 6.3 years, the overall survival in the entire group is 92% at 5 years (95% C.I.; 84%–96%), 83% at 10 years (95% C.I.; 70%–91%) and 78% at 15 years (95% C.I.; 62%–88%). Only one patient died for lymphoma (after histological transformation). Additional tumors were observed in 22%. A history of autoimmune disease was present in 15% of the patients and did not affect the outcome. Conclusions: Hp eradication usually results in long term disease control, independently of the lymphoma pathological remission status. A watch and wait policy seems safe in patients with local histological relapse with no endoscopic evidence of gross disease.
Prognostic Relevance of Ww-Oxidoreductase Gene Expression in Patientswith Acute Lymphoblastic Leukemia

Background: The WWOX gene (WW-Oxidoreductase) gene is frequently lower expressed in variety of tumor. Methods: Screening for WWOX gene expression was assessed using real-time reverse transcriptase polymerase chain in 50 ALL cases and 50 healthy control. Results: WWOX gene was significantly lower in ALL cases (0.43239 ± 1.38925) when compared with healthy control (10.501 ± 9.0338) (p=<0.001). No significant differences were found between high and low WWOX gene expression regarding clinical data, age, sex, hematological data. Patients who highly expressed WWOX gene achieved CR at significantly higher rates in ALL (p=0.002), and had significantly lower frequency refractory disease in ALL patients (p=0.017). Higher expression WWOX gene patients have statistically longer OS (p=0.049) when compared with low expression WWOX gene patients. Conclusion: Our result suggested that WWOX gene was a predictor for better outcome, could be a useful target for immunotherapy and might represent a candidate marker for monitoring of minimal residual disease.
Balsalazide-Induced Pneumonitis Causing Dyspnea in a Patient With Inflammatory Bowel Disease

ABSTRACT Inflammatory bowel disease complications can be related to inflammatory bowel disease-related pulmonary diseases or a form of hypersensitivity pneumonitis secondary to the immunosuppressive medications. We present a patient with intermittent chest pain and hypoxic respiratory failure who was found to have balsalazide-induced pneumonitis. We discuss the treatment and long-term outlook.