Miracle-dz/UniFAR-FTUs huggingface dataset:
The Broiling Soup of Retinoblastoma Genetics

Right from the time, two hit hypothesis of retinoblastoma was described to the present advancements in the field of genetics involving retinoblastoma; there has been a plethora of information available. The retinocytoma-retinoblastoma phenotype is attributed to the mutations occuring in RB gene locus; is a well known fact.Recently there has been add on researches on the same. The role of epigenetics and the role of genomic imprinting (selective expression of a gene) is new. This article tries to summarize the overwhelming information available in the field of genetics in retinoblastoma. It tries to clear the basic concepts about the hereditary retinoblastoma and it's various aspects. Also an attempt has been made to make the concept of maternal imprinting more clear in the article.
DENDROMETRIC CHANGES AS WATER STRESS INDICATOR FOR SUNFLOWER (HELIANTHUS ANNUS L.) AND MAIZE (ZEA MAYS L.) – BASIC RESEARCH IN LABORATORY CONDITIONS

Aim of the study The physiological impact of drought on the crop is reflected in the dendrological changes of the tree or plant body. In this study, we installed automatic dendrometers and we investigated the effect of irrigation dose at different intervals on the growth of sunflower and maize in laboratory conditions. Material and methods For our research, we have chosen sunflower (Helianthus annus L.) and maize (Zea Mays L.) sown in a laboratory equipped with Mars Hydro 400 LED lights as a substitute source of natural sunlight for 12 hours. Both crops were divided into containers A (irrigation dose of 5 mm was applied each day) and B (the same irrigation dose was applied at a 3-day interval). In every container, we have measured volumetric soil water content with 10HS sensors (by Decagon Devices) and dendrometric measurements of plants diameter with DD-S sensors (by Ecomatik). Results and conclusion A comparison of sunflower and maize irrigated at different intervals showed an increase in the diameters of stems at 1-day irrigation compared to 3-day by 0.8 mm (sunflower) and 12.0 mm (maize). The growth of plant mass was continuous at 1-day irrigation with minor fluctuations during the alternation of the dark and light phases. During the 3-day irrigation, greater shrinkage of the stems occurred, indicating the onset of water stress for the crops. The results of the work can be the basis for determining the appropriate application of irrigation bag in conditions of changing climate.
Literation And Financial Inclusion Among Creative Economic MSMEs; A Comparative Study

Abstract Micro, Small and Medium Enterprises are considered as sectors that are able to survive in the face of the economic crisis shock. However, there are some problems in running this Micro and Small and Medium Enterprises. This research is motivated by problems that hamper this development including limited management of financial management, human resources and access to capital. This is thought to have occurred because of low financial literacy among Small and Medium Enterprises. Therefore, this study aims to determine the condition and compare financial literacy and inclusion that is believed to help in the business development of the Creative Culinary Subsector of Micro Small and Medium Enterprises in the City of Cirebon with Cirebon Regency. The population in this study was 24,861 Micro Small and Medium Enterprises and 100 respondents. The sampling technique used purposive sampling with a sample size of 200 respondents or around 100 respondents in Cirebon City and 100 respondents in Cirebon Regency. While the analysis technique in this study uses multiple linear regression analysis with the help of SPSS Version 2.1 The results of this study that the variable Literacy and Financial Inclusion significantly influence the Development of Culinary Subsectors of the Creative Economy of Small and Medium Enterprises in the City and District of Cirebon. The comparative value is that the condition of Financial Literacy or Inclusion in the Cirebon City region is greater than in Cirebon Regency. Keywords: Financial Literacy, Financial Inclusion, Micro, Small and Medium Enterprises
Pulmonary Gangrene due to a Septic Emboli in a Young Female

Rationale: A rare case of necrotizing pneumonia secondary to septic DVT and use of ECMO and lung transplant in refractory respiratory failure. Objectives: To evaluate the role of ECMO and lung transplant in necrotizing pneumonia. Methods: We present a case report of a young female with Methicillin resistant necrotizing pneumonia, secondary to a septic deep venous thrombosis. Measurements: none Main results: ECMO may be employed in younger, healthy patients with limited comorbidities as in our patient. Conclusions: We present a successful ECMO application in a COVID -19 positive patient with severe ARDS
Effects of protein charge heterogeneity in protein-polyelectrolyte complexation

The interaction between globular proteins and synthetic polyelectrolytes was studied in 0.10 M NaCl solutions. pH titrations were used to induce the binding of three monomeric proteins of substantially different isoelectric points (BSA, chicken egg lysozyme and bovine pancreas ribonuclease) to polyelectrolytes with a range of charge densities. THe formation of soluble polyion-protein complexes is followed, upon progressive pH change, by phase separation (complex coacervation). Using known protein titration curves, the net charge on the protein at critical conditions could be calculated
The Application of Count Regression Models on Traffic Accidents in Case of Addis Ababa, Ethiopia

Road traffic accident is the major phenomena of the world as well as our country, Ethiopia which is from the low-income countries. Statistical modeling for count response variables is a primary interest in, insurance, and other areas. The main objective of this study is used to identify the most appropriate count regression model to fit the number of human deaths per road traffic accident (RTAs). The data for this study get from Addis Ababa Traffic Control, and Investigation Department (AATCID), daily basis recorded from July 30, 2013 to July 29, 2014. The difficultyassumption of Poisson regression model shifts to look for extended models like the negative binomial model, zero inflatedPoisson, and zero-Inflated Negative binomial regression models. Specifically, traffic accidents generate count response variables with an invalid assumption of Poisson distribution such thatthe variance and mean of human death per road traffic accident are (0.58) and (0.36), and the overdispersion parameter under the negative binomial was detected to indicate the existence of over-dispersion implies ZIP (or ZINB) model is favored over the Poisson (or NB) model, respectively, by using Vuong test. By using the goodness of fit model criteria like LRT, AIC, and BIC zero-inflated Poisson (ZIP) is the most fitted model for road traffic accident dataset.Therefore, quarter of year, slope of road, age of driver, vehicle type and ownership, time of accident, and type of accident are found statistically significant factors at α = 0.05fornumber of human death per road accidents.
Polymorph selection: challenges for the future?

This contribution reviews the area of polymorph selection during solution crystallization using known and predicted structures. In particular, an overview of what has been learned about the relationship between structure and kinetics and of the interplay between thermodynamics and kinetics is presented. This review adds to the debate by discussing the future challenges that we envisage in realizing polymorph selection as a crystal engineering exercise by highlighting the role that a packing landscape approach may contribute in manipulating the selection of a polymorph.
New Antiarrhythmic Agent to Stabilize Functional Activity of Rat Heart Sinus Node Cardiomyocytes

Introduction: The aim of this study was to explore the antiarrhythmic activity of the new antiarrhythmic drug, succinic acid ester of 5-hydroxyadamantane-2-one (ADK-1110) and its effect on the functional activity of rat heart sinus node. Materials and methods: Experiments were performed on 80 non-linear white awake male rats weighing 200 g, using calcium chloride and aconitine arrhythmia models. The ECG was recorded from all the animals in the II standard lead before the start of the experiment. The effect of ADK-1110 on the electrical activity characteristics of rat heart sinus node pacemakers in vitro was studied on 26 outbred Wistar rats of both sexes with a body weight of 160 to 200 g, using the microelectrode technique. Results and discussion: The compound significantly exceeds the known reference drugs in terms of the antiarrhythmic index. The agent also surpasses our previously proposed adamantane derivative ADK-1100 on calcium chloride model and is not inferior to the aconitine one. The electrophysiological analysis of the sinus node pacemaker cardiomyocytes characteristics in vitro under the influence of ADK-1110 revealed that the compound expands the area occupied by true pacemakers. Discussion: The obtained data indicate the presence of properties of antiarrhythmics of classes I, III, and IV in ADK1110. The indicated functional remodeling stabilizes the functional activity of the central part of the sinus node. Conclusion: ADK-1110 stabilizes the functional activity of the central part of the sinus node. ADK-1110 also has a cerebrovascular anti-ischemic property.
Influence of Malt on Rheological and Baking Properties of Wheat–cassava Composite Flours

Wheat flour was partially substituted with cassava flour at various levels. Malt was added at different levels to the composite flour and the resultant blends were evaluated for α -amylase activity and rheological properties. The best blends were selected based on α -amylase activity and rheological properties for making bread. The α -amylase activity of wheat–cassava composite flours was Enhanced by the addition of 1% malt and judged to be suitable for making bread. Addition of malt to the composite flours did not affect the water absorption and reduced the mixing time. Also, dough stability, strength of flour and weakening of dough of composite flours were improved by the addition of 1% malt. Wheat flour substituted with 20, 30, 40 and 50% cassava flour with 1% malt were selected for making bread. Loaf height, loaf volume, oven spring and specific volume obtained from composite flours at 20 and 30% cassava substitution level and 1% malt were not significantly different to that of control bread obtained from 82% extraction ratio wheat flour. Sensory evaluation of the bread obtained from composite flours at 20 and 30% cassava substitution level and 1% malt had acceptable sensory qualities similar to that obtained from wheat flour 82% extraction ratio.
Peranan Hormon Ghrelin dalam Fungsi Reproduksi

Ghrelin lebih dikenal sebagai hormon lapar atau hormon yang mengatur siklus kenyang-lapar mahkluk hidup. Fungsi reproduksi ghrelin mencakup aksi hipotalamus-hipofisis-gonad (ovarium dan testis) dan juga hormon reproduksi lain. Selain itu ghrelin juga diketahui memiliki pengaruh pada proses patologis beberapa penyakit pada kehamilan dan infertilitas.Ghrelin is better known as a hunger hormone or a hormone that regulates the cycle of satiety- hunger. The reproductive function of ghrelin includes action to the hypothalamus-pituitary-gonad (ovary and testis) axis and other hormones. Ghrelin is also known to influence the processes of several diseases in pregnancy and infertility.
Hniezdne spoločenstvá vtákov vo vzťahu k štruktúre urbánneho prostredia malého mesta (Sabinov, východné Slovensko)

In the present study, we explored the effects of urban habitat attributes on richness, density and community composition of breeding birds. We performed the study during breeding season within a small town (c. 12,000 inhabitants) in eastern Slovakia in 2019. We assessed bird data and habitat characteristics for seven zones (town centre, an old detached houses’ residential area, a recent detached houses’ residential area, industrial zone, a high-rise buildings’ residential area, greenway) within the study area (347 ha). We found 40 breeding species and 2,033 breeding pairs within the area. The bird species were classified into six nesting guilds (building-nesters, hole-nesters, tree-crown-nesters, shrub-nesters, ground-nesters, and riparian cavity-nesters) and to four groups with different affinity to urban environment. The building-nesters were the most abundant guild followed by treecrown-nesters. We found that maximum tree height and ruderal vegetation cover correlated positively with overall species richness, and maximum number of buildings’ floors correlated positively with overall abundance (per 10 ha). Abundance of hole-nesters, tree-crown-nesters and shrub-nesters correlated positively with tree cover, and negatively with cover of hard surfaces; building-nesters’ abundance was positively correlated with maximum number of buildings’ floors. Tree cover and maximum number of buildings’ floors explained 50.7% of species composition in zones. Composition of nesting guilds differed between the town zones. Our results indicate the importance of urban vegetation to maintain higher breeding bird species richness in town environment.
ANALYSIS OF EDUCATION LEVEL AND INCOME EFFECT TO THE NUMBER OF POOR INHABITANT IN INDONESIA

This research aims to analyze the level of education and income per capita of the number of poor people in Indonesia in 2004 - 2019 either partially or simultaneously. The population in this study was Indonesia in 2004 - 2019. The sampling technique is purposive sampling technique. The data collection method is documentation. Although the method of analysis using regression analysis techniques of time series data. The results of data analysis showed that the level of education is partially significant effect on the number of poor people in Indonesia. On the other hand revenues significantly influence the number of poor people in Indonesia. While simultaneously the levels of education and income influence significantly to the number of poor people in Indonesia.
Surface Grafting on Polymer Surface Using Physisorbed Free Radical Initiators

A new strategy for creation of radicals on an inert polymer surface has been developed. This new method combines free radical polymerization with a surface graft polymerization. The polymer film, poly(dimethylsiloxane) (PDMS), was selected as an inert model material and was immersed into acetone containing azo-bis-isobutyrylnitrile (AIBN). We speculate that the AIBN becomes physically adsorbed or partially penetrates the hydrophobic polymer surface. The polymerization of water-soluble monomers was initiated by the absorbed initiator and polymer surface became modified by the hydrophilic monomers. We speculate this process was facilitated by the poor diffusion of physisorbed radicals derived from AIBN into an aqueous medium. ATR−IR, XPS, and contact angle measurements were used to characterize the surface modification. This method provides a potential modification method for the coating of many polymer surfaces possessing complicated geometrical shapes. The principle relies on the insolubility of the physi.
Heterogeneous reactions on the surface of fine particles in the atmosphere

Fine particles play an important role in the atmosphere. Research on heterogeneous reactions on the surface of fine particles is one of the frontier areas of atmospheric science. In this paper, physical and chemical characteristics of fine particles in the atmosphere and the interactions between trace gases and fine particles are described, methods used in heterogeneous reactions research are discussed in detail, progress in the study of heterogeneous reactions on the surface of fine particles in the atmosphere is summarized, existing important questions are pointed out and future research directions are suggested.
Wear prediction of piston/cylinder pair in axial piston pump

The piston/cylinder pair is the key lubricating interface of axial piston pumps. It suffers from excessive wear due to the huge lateral force, especially under high output pressure. In order to achieve predictive maintenance, it is significant to detect the performance degradation of the piston/cylinder pair. In this paper, a method to predict the wear of the piston/cylinder pair is proposed. The wear regions and corresponding wear depths under different conditions are investigated. The distributive characteristic parameters of the oil film are obtained, which can reflect the load-bearing and lubrication conditions at each region of the friction pair. Based on the oil film characteristic parameters, the most suitable wear model is chosen to calculate the wear depth, and then the entire wear profile of the piston/cylinder pair is obtained. The experimental investigation is carried out, and the results show that the accuracy of the wear regions and corresponding wear depth prediction is high. This method can be used to pump healthy management and choose the suitable working conditions of the axial piston pump.
PERFORMANCE AND INTESTINAL MORPHOMETRY OF NAKED NECK BIRDS FED TREE CASSAVA HAY

Tree cassava, a plant native of the caatinga, has been used frequently in the livestock production, especially ruminants. However, the effects of this inclusion in poultry diets is still poorly understood. Basal diet was partially substituted with tree cassava (Manihot psdeudoglaziovii) hay in the feeding of naked neck Label Rouge birds reared in semiarid climate. It was evaluated the effects on food intake, weight gain, feed conversion from 33 to 70 days of age (d), relative weight of prime cuts and edible organs at 70d, and the histology of small intestine at 56d. An economic analysis of the use of tree cassava hay was also carried out. Three hundred Label Rouge birds were distributed at 33d into a completely randomized design with three treatments (0, 7 and 14% of tree cassava hay levels) and ten repetitions with ten birds per repetition. There were no differences on feed intake, although tree cassava levels negatively affected weight gain and feed conversion. Relative gizzard weight increased (P<0.05) with higher tree cassava levels. In the duodenum, villus height increased (P<0.01) in birds fed 7% tree cassava hay; crypts were deeper in all segments of birds fed 14% tree cassava hay. Relative gross profit decreased in any scenario simulated with 14% of tree cassava hay. The substitution of tree cassava hay for basal diet at the level of 7% is viable for naked neck Label Rouge birds reared in semiarid climate.
Awareness and Treatment of Cancer-Related Depression

Cancer is one of the main causes of death and the incidence rate is increasing. Depression is one of the most common negative psychological states of patients. Cancer-related depression (CRD) refers to the emotional pathological reaction of patients who lose their personal mental normality due to diagnosis, treatments and comorbidities [1]. It is reported that the incidence of CRD is 3.7% -58 % [2].
The Barriers and Obstacles of Attitude towards Online Shopping in the Malaysian Market

This review paper focuses on the barriers and obstacle of attitude towards online shopping in the Malaysian market. From the review of literature, it is found that the Malaysian online shopping is still at the beginning stage as compared to other Asian countries which are at a more advanced stage. Among the contributor to this issue is the lack of understanding and negative attitude towards online shopping. Due to that, four main barriers have been identified and they are: privacy and security, trust, web design and perceived ease of use. This study is still at the early stage and needs further validation by reputable scholars and experts in the field to enhance its credibility. Thus, the issue will be explored further through quantitative study.
Studi Konsep Pengaruh Kualitas Pelayanan Terhadap Kepuasan Pelanggan di PT. PLN (Persero) Sebagai Perusahaan Penyedia Energi Listrik Monopoli

Abstrak — Salah satu parameter yang digunakan pelaku bisnis untuk mengukur kinerjanya adalah melalui kualitas layanan. Dalam tulisan ini, dijelaskan konsep pengaruh kualitas pelayanan terhadap kepuasan pelanggan pada PT. PLN (Persero) yang menyediakan energi listrik kepada konsumen. Selain itu juga melihat faktor kualitas pelayanan yang turut berperan dalam menjelaskan kepuasan pelanggan pada perusahaan. Hasilnya menunjukkan bahwa tingkat kualitas pelayanan yang telah diberikan kepada pelanggan sangat mempengaruhi kepuasan pelanggan. Juga menunjukkan perlunya sosialisasi kepada karyawan perusahaan bahwa pelanggan perlu mendapat perhatian penuh sebagai klien atau pelanggan yang membeli produk dan jasa perusahaan. Kata kunci : kualitas pelayanan, kepuasan pelanggan, PT. PLN (Persero) Abstract — One of the parameters used by business people to measure their performance is through service quality. In this paper, the concept of the influence of service quality on customer satisfaction at PT. PLN (Persero) which provides electrical energy to consumers. In addition, it also looks at the service quality factors that play a role in explaining customer satisfaction at the company. The results show that the level of service quality that has been provided to customers greatly affects customer satisfaction. Also shows the need for outreach to company employees that customers need to get full attention as clients or customers who buy company products and services. Keywords : service quality, customer satisfaction, PT. PLN (Persero)
A Multilayer Motion Direction Based Model for Tracking Vehicles at Intersections

Visual vehicle tracking is an important topic in intelligent transportation systems. Intersections are challenging locations for visual systems to track vehicles which are moving in different directions, simultaneously. In addition, the normal traffic flow may change at intersections due to accidents. Congestion, occlusion and undetermined motion flows are the nominated challenging issues of vehicle tracking at intersections. In this paper, a method for tracking multiple vehicles is proposed considering the vehicle motion directions to overcome undetermined motion flows. For this purpose, a multilayer model is presented, which assigns each motion flows to distinct layers. Moreover, we introduce different neighborhoods for various layers considering the regular motion flows in a layer. Hence, vehicles entering from the same side of intersection with the same motion direction are assigned to the same layer. Then the tracking is performed on different layers separately. In special cases such as vehicles crossing each other, misdetections or occlusion, the proposed tracking method can predict the vehicles tracks by using the stored tracking history and considering neighborhoods in that layer. Experimental results show consistency between proposed tracking method results and ground truth, also outperformance of other tracking methods in tracking vehicles crossing the intersection.