Miracle-dz/UniFAR-FTUs huggingface dataset:
Das Ulcus adiposo-venosum – eine therapeutische Herausforderung Ulcer adiposo-venosum – a therapeutic challenge

Zusammenfassung Hintergrund: Die kausale Therapie eines Ulcus cruris venosum stellt bei adipösen Patienten eine therapeutische Herausforderung dar. Methode: Anhand eines Fallberichts wird die Vorgehensweise demonstriert: mittels Sourcing kann auch bei schwerer Adipositas eine ulkusrelevante Varize detektiert und erfolgreich schaumsklerosiert werden. Ergebnisse: Die erfolgreiche Schaumsklerosierung der im Sourcing relevanten Varize hat keinen Effekt auf die Ulkusheilung. Schlussfolgerung: Stigmata der chronischen venösen Insuffizienz finden sich bei adipösen Patienten als Folge eben der Adipositas, so dass eine Gewichtsreduktion als kausale Therapie gelten kann. In unserem Fall kann von einem Ulcus adiposo-venosum gesprochen werden. Summary Background: The causal therapy of a venous leg ulcer is a therapeutic challenge in obese patients. Method: Based on a case report, the procedure is demonstrated: Sourcing can be used to detect ulcer-relevant varices even in severe obesity and to successfully foam-sclerose them. Results: The successful sclerotherapy of the sourcing-relevant varices has no effect on ulcer healing. Conclusion: Stigmata of chronic venous insufficiency are found in obese patients as a result of obesity, so that weight loss can be considered a causal therapy. In our case, one can speak of an ulcer adiposo-venosum. English version available at: www.phlebologieonline. de
Optimization of a Single Model U-SLAB with Stochastic Duration with Integration of Genetic Algorithm and Computer Simulation

In this study, a simulation optimization method is applied in order to find the optimal design of a U-shape assembly line. The optimality criterion is the minimum number of needed stations. While many previous works use deterministic models to solve this problem, a simulation approach is applied in this study to consider the stochastic nature of the problem. On other hand, when we use a simulation method, a better understanding of system behavior can be obtained through the evolution of system. Another case that is considered in this study is the failures of conveyers which happen in the real world and the fatigue of operators is considered too. The procedure is as follows: first, an initial design of system is obtained by an optimizer (here Genetic Algorithm) with an initial given parameters. Second, the output of the optimizer is used to implement a simulation model in Visual Slam. Third, after running the model in simulator, the desired outputs are evaluated and the necessary changes will be made to optimizer parameters. Fourth, again the optimizer is used to generate new design with new parameters.
RAPID SEQUENCE INDUCTION WITH ROCURONIUM AT 0.45 MG/KG: COMPARISON OF INTUBATING CONDITIONS BETWEEN KETAMINE AND PROPOFOL INDUCTION

Abstract Introduction Methods Results p =0.499). Fraction of excellent intubating conditions was 67.5% and 57.5% in group K and group P, respectively ( p =0.356). No difference in the twitch suppression at the time of intubation or the onset time of rocuronium was observed. After induction, group K presented signi fi cantly increased blood pressure, which was higher than in group P ( p =0.000). Discussion and conclusion fi rmed in this study. Ketamine or propofol at 2.5 mg/kg and rocuronium at 0.45 mg/kg provided clinically acceptable intubating conditions at 75 seconds after rocuronium in the majority of patients studied. This technique may be applied in RSI, when suxamethonium is contraindicated and a short duration of neuromuscular blockade is needed. The choice of either induction agent therefore depends mainly on its hemodynamic effects. Chiang Mai Medical Journal 2010;49(1):11-17. When compared with propofol, ketamine is likely to produce better intubating conditions, due to its analgesic and hemodynamic effects, but this was not con All patients in both groups were successfully intubated at the fi rst attempt. Clinically acceptable intubating conditions (good or excellent) were obtained in 90% of group K compared to 85% of group P ( Eighty ASA 1-2 adult patients, who required tracheal intubation during anesthesia for elective surgery, were randomly assigned to receive either ketamine at 2.5 mg/kg (group K) or propofol at 2.5 mg/kg (group P) followed by rocuronium 0.45 mg/kg. Tracheal intubation was performed at 75 seconds after administration of rocuronium. The intubating conditions, twitch suppression of the adductor pollicis and hemodynamic responses were evaluated. Rocuronium is an alternative neuromuscular blocking agent used during rapid sequence induction (RSI) when suxamethonium is contraindicated. However, the optimal intubating dose of rocuronium is 1 mg/kg, which is associated with a long duration of action. The aim of this study was to compare the intubating conditions after a relatively low-dose of rocuronium (0.45 mg/ kg) in simulated RSI between ketamine and propofol induction.
A Review of Natural Ventilation Measurements Using Tracer Gas Techniques

Introduces the principle of natural ventilation measurements by using tracer gas techniques and the features of three measuring methods.Some relative factors(type and amount of tracer gas,testing methods,testing scheme and date processing) were discussed to find the main factors in this paper based on the widely adopted tracer decay method,then put forward some improvement ideas for the main factors.y as the simulation only using TRNSYS,but also it can be more convenient than the simulation only using TRNSYS.
Analysis of human avoidance motion for application to robot

The possibility of applying human avoidance motion to robot is considered. Our target of human avoidance motion in this study is passing motions. Two experiments, the passing motion experiments on the road and in the laboratory, were conducted to construct the robot avoidance motion algorithm by using human avoidance motion. The characteristics of the avoidance algorithm were obtained by the analysis of the result from the experiment on the road. From the result of the experiment in the laboratory, it was found that when the subjects were walking at an almost constant velocity and passed each other, the locus could be approximated into a catenary. The avoidance algorithm was constructed based on the data obtained from all the experiments, and the area of human's space was calculated. In addition, the avoidance motion simulation of the robot using the avoidance algorithm obtained has been performed.
Insights into Inservice Teachers’ Video-Facilitated Reflection of Literacy Practices

Abstract Purpose This chapter serves to synthesize existing literature centered on inservice teacher video-facilitated reflection on literacy pedagogy. Methodology/approach The inservice teacher literature review is focused on: (1) video analysis frameworks and scaffolds used to facilitate inservice teachers’ video reflection; (2) reflection and video discussions; and (3) the use of video for inservice teacher change and development. Findings From this review we learn that there is a dearth of video reflection research with inservice teachers on literacy pedagogy. Within the field of literacy, we know far less about how, when, and why to use video with inservice teachers than preservice teachers. Research limitations/implications The review of literature does not incorporate inservice teacher video reflection in disciplines such as science and mathematics. Expanding this review to all disciplines would present a more comprehensive picture of video reflection with inservice teachers. Practical implications The chapter highlights the potential value of using video in inservice professional development and points to the specific needs for studies to identify the most effective uses of video specific to inservice professionals. Originality/value This chapter provides significant research-based information for designing and implementing future studies and professional development focused on video reflection with inservice teachers.
Formant-contour models of diphthongs : a study in acoustic phonetics and computer modelling of speech

This thesis advances understanding of the dual vocalic nature of diphthongs by addressing the fol'lowing question in the acoustic phonetic domain: does the vocalic duality arise simply from a static combination of two vowels as the traditional biphonemic representation of diphthongs tends to suggest, and how is the duality manifest in the time-varying formant-patterns of diphthongs? This fundamental question regarding diphthongs has hitherto not been addressed nor answered satisfactorily from either methodological or conceptual viewpoints. In particular, the sparse-sampling approach used consistently in previous studies to describe the contours of the first three formants (Fi, F2 and F3) of diphthongs attests to a long tradition which does not properly acknowledge the time-varying characteristics of the movement from onset to offset vowels. Moreover, basic understanding of the diphthong has progressed little beyond the conventional matching of two vowels, one to the onset and the other to the offset points of the Fiand Frcontours of the diphthong. In contrast, the approach adopted and advocated in this thesis attends to the detailed time-varying behaviour of not only the Fi and F2 , but also the F3 of diphthongs which are shown to play, jointly with the F2 , an important role in identifying two distinct parts of these ? peech sounds. To this end, a new method of formant estimation is employed, which secures temporal continuity along the Fi-, Fr and F3-contours of vocalic sounds. Mathematical models are then offered which (1) capture the essential contour behaviour of the first three formants of diphthongs; and (2) yield parameters which convey information about the dual vocalic nature of these speech sounds, not only in static but also in dynamic terms.
Quantum resource theories in the single-shot regime

One of the main goals of any resource theory such as entanglement, quantum thermodynamics, quantum coherence, and asymmetry, is to find necessary and sufficient conditions (NSC) that determine whether one resource can be converted to another by the set of free operations. Here we find such NSC for a large class of quantum resource theories which we call affine resource theories (ART). ARTs include the resource theories of athermality, asymmetry, and coherence, but not entanglement. Remarkably, the NSC can be expressed as a family of inequalities between resource monotones (quantifiers) that are given in terms of the conditional min entropy. The set of free operations is taken to be (1) the maximal set (i.e. consists of all resource non-generating (RNG) quantum channels) or (2) the self-dual set of free operations (i.e. consists of all RNG maps for which the dual map is also RNG). As an example, we apply our results to quantum thermodynamics with Gibbs preserving operations, and several other ARTs. Finally, we discuss the applications of these results to resource theories that are not affine, and along the way, provide the NSC that a quantum resource theory consists of a resource destroying map.
Innovation und Evaluation in der Chirurgie

Zusammenfassung Innovation und Evaluation werden in der Chirurgie häufig als Gegenspieler betrachtet. Vermeintlich hemme die Evaluation durch prospektive Studien die Innovationskraft des einzelnen Chirurgen oder der Industrie. Dieser Artikel beleuchtet das Themengebiet der Evaluation durch Studien in der Chirurgie und zeigt auf, inwiefern Evaluation hilft, Innovation zu fördern und dabei einen wichtigen Beitrag zur Verteilung der Ressourcen im Gesundheitswesen leistet. Nur im Zusammenspiel zwischen Innovation und Evaluation kann sichergestellt werden, dass es nicht nur vorangeht, sondern auch die Richtung stimmt.
CURRENT MECHANISMS OF ACTION IN TREATMENT OF CHRONIC CONSTIPATION AND IRRITABLE BOWEL SYNDROME

Patients with chronic constipation and irritable bowel syndrome (IBS) have a variety of potential treatment options. Treatment typically begins with lifestyle changes and fiber supplementation. The predominant lifestyle changes are alteration of fluid intake, dietary modification, and physical activity. Laxatives constitute the second line of therapy. Patients can avail themselves of various emollient, osmotic, and stimulant laxatives. Among all the laxative agents, the strongest supporting evidence is for lactulose and polyethylene glycol. These conventional therapies have highly variable rates of therapeutic success. Most patients cope with their symptoms and are less than completely satisfied with therapy. Newer therapies have provided additional options that may help improve symptom relief and patient satisfaction. The 5-HT4 serotonin agonist tegaserod has demonstrated efficacy for chronic constipation and constipation-predominant IBS and is approved for treatment of men and women with chronic constipation and for women with IBS. The chloride channel activator lubiprostone recently was approved for treatment of constipation in men and women. The 5-HT3 antagonist alosetron has approval for treatment of diarrhea-predominant IBS in women. A host of investigational agents are in various stages of evaluation and clinical development, many of which represent new approaches to treatment of chronic constipation and IBS. (Adv Stud Med. 2006;6(4A):S237-S242) I n considering treatment options for chronic constipation, physicians should keep in mind the profile of a “typical” patient. Typically, the patient is female more often than male and has been symptomatic for more than 10 years. The majority of patients have tried lifestyle changes, fiber, and over-the-counter laxatives before seeking care. They manage their condition with several therapies. Most often, they are referred to the gastroenterologist by a primary care physician. A key point is that the typical patient copes with his or her constipation but is not completely satisfied with the treatment that is available, and therefore, a great deal of room exists for improvement. The American College of Gastroenterology (ACG) Chronic Constipation Task Force has evaluated the many therapies available for chronic constipation in terms of the evidence available to support their use and their ability to alleviate constipation. Therapies were given a grade of A, B, or C depending on the level of evidence available to support their use. The Table lists the 4 levels of evidence, that were identified. Understanding the strength of a particular recommendation provides a context for evaluating available therapies for constipation and making treatment decisions that best meet the needs of our patients.
Conversations With Strangers: The Needs of Those Accessing a Palliative Care Nurse Practitioner on a Pancreatic Cancer Web Site

The Internet is increasingly a resource for cancer information and support. Those with pancreatic cancer may have particular needs, given the disease’s short trajectory and high mortality. The purpose of this study was to identify the palliative issues of those accessing a Web page where they could interact with a palliative care nurse practitioner and to determine the type of responses the palliative care nurse practitioner provided. A qualitative descriptive approach was used. Content from questions and e-mails to the palliative care nurse practitioner was analyzed, and primary and secondary issues identified. When possible, each issue was clustered within 1 of the 8 palliative care domains. Palliative care nurse practitioner responses were also analyzed and categorized. Forty-eight participants posted 55 questions to the palliative care nurse practitioner. The majority of primary issues (57%) fell into one of the palliative care domains. Forty-two percent asked about physical aspects of pancreatic cancer, with the next largest domain, 11%, being psychological concerns about the illness. Participants were concerned about symptoms, were uncertain about prognosis, and lacked education on what to expect. A few seemed unaware their loved ones were in the last stage of pancreatic cancer. Access to information, support, and palliative care is important for people dealing with pancreatic cancer. The Internet provides an opportunity to address some of their issues.
Raincloud Founded Hypermedia Relaxed Security Scheme

Distribution of copyrighted multimedia objects by means of uploading visitors to online hosting sites can effect in primary insufficient revenues for content creators. Systems required to uncover clones of multimedia objects take time and effort and important. We advise a manuscript the thought of important multimedia content protection systems. We focus on the approach to protecting multimedia content, that's content-based copy recognition through which signatures are acquired from original objects. Our physiques for multimedia content protection discover unlawfully made copies of multimedia objects on the internet. Our design attains fast employment of content protection systems, as it is based on cloud infrastructures that offer computing hardware in addition to software sources. It's two new components like a method of generate signatures of three-dimensional and distributed matching engine for multimedia objects.
A phase 1 study evaluating the safety, pharmacokinetics, and efficacy of ABT-263 in subjects with refractory or relapsed lymphoid malignancies

8511 Background: ABT-263 is a novel BH3 mimetic that binds with high affinity (Ki 1 nanoM) and inhibits multiple antiapoptotic Bcl-2 family proteins. ABT-263 displays potent mechanism-based cytotoxicity (EC50 1 microM) against human cell lines derived from lymphoid and small cell lung cancers. The anticipated ABT-263 associated toxicities are mechanism based, in particular, Bcl- XL mediated decrease in circulating platelet survival, Bcl-w mediated testicular toxicity, and Bcl-2 mediated effects on lymphocytes. Methods: The safety and pharmacokinetic (PK) profile of ABT-263 were studied in patients with relapsed or refractory lymphoid malignancies. For each 21-day cycle, subjects received ABT-263 orally QD for 14 consecutive days followed by 7 days off drug. The drug dose was doubled in each cohort until a grade 3 toxicity occurred, after which escalations were in 40% increments. Results: Currently, 30 patients have been enrolled in the lymphoma study completing the 10, 20, 40, 80, 160, 225 and 315 mg coho.
The Timeless Way of Building

An apparatus for investigating the course of fast chemical reactions, which are initiated in a liquid chemical system under investigation by an external perturbation, e.g. a steep temperature rise (temperature jump). The apparatus comprises first and second light paths conveying a probing light beam and a sense light beam, respectively, and an optical system of extremely high aperture which allows a wide variety of types of measurements, including absorption, fluorescense, fluorescense polarization, and the like with a high signal-to-noise ratio even of small sample concentrations.
Synthèse immersive de sons d'environnement

La plupart des outils disponibles pour la sonorisation d’environnements virtuels sont bases sur l’utilisation de tables d’onde : des sons sont pre-enregistres et declenches en temps reel selon les actions de l’utilisateur dans le monde virtuel. Les techniques de spatialisation sont souvent integrees dans un second temps pour simuler la reverberation et les proprietes spatiales des sources, comme la position, la directivite et l’extension spatiale. Ce travail de these propose une approche originale pour la synthese et la spatialisation des sons d’environnement. Nous concevons un synthetiseur temps-reel qui permet de generer des sources sonores diverses (pluie, vent, feu, vagues, impacts. . . ), de les controler via des parametres “haut-niveau”, et de les manipuler dans un espace virtuel 3D. Apres une revue des modeles de synthese existants pour diverses sources environnementales, nous specifions un modele de synthese generique base sur la synthese additive et sur cinq structures sonores parametriques appelees “atomes”. Une combinaison adequate de ces atomes permet de creer des sources associees aux trois categories de sons d’environnement : les solides en vibration, les sources aerodynamiques et les liquides. Le moteur du synthetiseur integre efficacement synthese et spatialisation au meme niveau de la generation du son. Nous utilisons l’implementation de la synthese additive par transformee de Fourier inverse avec un choix de parametres adapte. Le rendu sonore 3D est compatible avec les formats audio standard (multi-canal, ambisonics, binaural) permettant une ecoute sur haut-parleurs ou au casque. Nous presentons egalement une methode de synthese basee sur un formalisme en “sous-bande” qui permet de generer des signaux stochastiques necessitant une resolution fine a la fois en temps et en frequence (comme des sons d’impact ou de feu). Enfin, des controles “haut-niveau” sont specifies pour manipuler intuitivement le synthetiseur a partir de proprietes physiques telles que “la force du vent” ou “l’intensite du feu”. Nous proposons egalement un controle d’extension spatiale, valide par un test perceptif formel, qui permet de simuler des sources naturellement non ponctuelles comme la pluie ou les vagues. Le controle conjoint du timbre et des proprietes spatiales des sources permet de creer intuitivement des scenes sonores complexes et immersives.
Blockchain-Based Software-Defined Industrial Internet of Things: A Dueling Deep ${Q}$ -Learning Approach

With the developments of communication technologies and smart manufacturing, Industrial Internet of Things (IIoT) has emerged. Software-defined networking (SDN), a promising paradigm shift, has provided a viable way to manage IIoT dynamically, called software-defined IIoT (SDIIoT). In SDIIoT, lots of data and flows are generated by industrial devices, where a physically distributed but logically centralized control plane is necessary. However, one of the most intractable problems is how to reach consensus among multiple controllers under complex industrial environments. In this paper, we propose a blockchain (BC)-based consensus protocol in SDIIoT, along with detailed consensus steps and theoretical analysis, where BC works as a trusted third party to collect and synchronize network-wide views between different SDN controllers. Specially, it is a permissioned BC. In order to improve the throughput of this BC-based SDIIoT, we jointly consider the trust features of BC nodes and controllers, as well as the computational capability of the BC system. Accordingly, we formulate view change, access selection, and computational resources allocation as a joint optimization problem. We describe this problem as a Markov decision process by defining state space, action space, and reward function. Due to the fact that it is difficult to solve this joint problem by traditional methods, we propose a novel dueling deep ${Q}$ -learning approach. Simulation results are presented to show the effectiveness of our proposed scheme.
Rxiensing scan chains for test pattern decompression

The paper presents a method for testing a system-on-a-chip by using a compressed representation of the patterns on an external tester: The patterns for a certain core under test are decompressed by reusing scan chains of cores idle during that time. The method only requires a few additional gates in the wrapper; while the mission logic is untouched. Storage and bandwidth requirements for the ATE are reduced significantly.