Miracle-dz/UniFAR-FTUs huggingface dataset:
Pharmacokinetics of albendazole and albendazole sulfoxide after oral administration to farm chicken

The present study was conducted to determine the pharmacokinetic parameters of two anti-parasite drugs: albendazole and albendazole sulfoxide, following oral administration to farm chicken at a single dose of 10 mg/kg body weight. The experiment was done on eight male adult chickens. The HPLC technique was used to determine drug concentrations in plasma. Various pharmacokinetic parameters, including the area under curve (AUC), the maximum plasma concentration (Cmax), the maximum concentration (T max), and the mean residence time (MRT), were determined for both anthelmintics and their metabolites albendazole sulfoxide (ABZSO) and albendazole sulfone (ABZSO2). The ABZ was detectable up to 32 hours with a maximum plasma concentration Cmax of (0.393-0.557ug/ml) and its metabolites ABZSO and ABZSO2 were detected with a Cmax of (0.393-0.557 ug / ml) and (0.393-0.557ug /ml) with a Tmax of (6.75 , 3.49h) and (16.125-6.59h, respectively. The metabolites of ABZ remain detectable up to 48 hours. The administration of ABZSO to farm chicken showed better bioavailability compared to ABZ. In conclusion, both anthelmintics showed more favorable pharmacokinetic results on farm chicken compared to data collected on broiler chicken.
Reasons-Responsiveness, Agents, and Mechanisms

Many philosophers are convinced by Harry Frankfurt’s (1969) controversial argument that moral responsibility does not require the ability to do otherwise. According to Frankfurt, it is possible to construct an example in which an agent acts freely and is morally responsible for what she does but is unable to do otherwise. Frankfurt’s example featured Jones, who shot Smith for his own reasons. As it happened, Black wanted Jones to shoot Smith on his own, but covertly arranged things so that if Jones were about to fail to do so, Black would manipulate Jones so that he (Jones) would shoot Smith. Since Jones shot Smith on his own, Black remained dormant; he played no role in Jones’s act. Jones, it seems, acted freely and was morally responsible for doing so. Yet because of Black’s presence, Jones could not have done otherwise. Hence, as the example involving Jones illustrates, moral responsibility does not require the ability to do otherwise.2
Cognitive Presence in a Blended Learning Environment at Jordanian Universities

Cognitive presence is the ability of the learners to project their mental and perceptual presence. This paper aims to investigate cognitive presence when using a Blended Learning environment. The article also aims at exploring university students' attitudes towards using a BL environment in language learning, since BL perception, as a computer learning environment, has become a requirement to enhance language learning. The sample for the study consists of 100 students studying the English Language Skills course at Al-Balqa Applied University (BAU) in Jordan, who responded to a questionnaire on cognitive presence issues. The findings of the study reveal that Blended Learning (BL) can create a vibrant cognitive presence, which enables to support active language learning. The results share some positive attitudes towards a cognitive presence in a BL environment. The study recommends that more research on the part of the online instructors to create and enhance cognitive presence is necessary to benefit learning English language skills.
CUSTOMIZING USER SEARCH RECORDS

Users are increasingly pursuing multifaceted task-oriented goals on the Web, such as making travel arrangements, managing finances or planning purchases. Each step requires one or more queries, and each query results in one or more clicks on relevant pages. To support users in their long-term information quests on the Web, “Customizing User Search Records” helps to keep track of their queries and clicks while searching online. The aim is to organize a user’s historical queries into groups in a vibrant and automated fashion. Automatic identification of query groups is helpful for a number of different search engine components and applications, such as query suggestions, result ranking, query alterations, sessionization, and collaborative search. The existing approaches rely on textual similarity or time thresholds. In this paper we use query reformulation and click graphs that will contain useful information on user behavior when searching online. Then the query fusion graph merges the information in the query reformulation graph and click graph and the approach based on probabilistic random walks over the query fusion graph outperforms time-based and keyword similarity based approaches to customize user search records in different groups. This is the robust approach that leverage search query logs.
TACTILE CREASE

In Poland, in vitro fertilization (IVF) is often a contested procedure, as it is not accepted by Catholic bioethics. This rejection mobilizes a wide range of views and arguments about IVF, some of which circulate only in the local discourse. A very potent local concept is the “tactile crease” (bruzda dotykowa) that is said to mark the foreheads of children conceived with IVF. This term, coined in 2013 by a priest who is also a professor of law, represents one way in which the political discourse shapes the imagined body of the Other. In this paper, the analysis of the origins and resonance of the “tactile crease” in the Polish public discourse is confronted with the results of anthropological research among children conceived with IVF and their families.
Deformation and Acoustic Emission Characteristics of Cracked Granite during Creep

A series of multistage creep tests under different confining pressures with acoustic emission monitoring have been performed to investigate the deformation characteristic and failure process of cracked granite during creep. The critical axial strain of cracked sample showed an increasing tendency with the increase of confining pressure. In contrast, critical lateral strain experienced a process of descending first at low confinement and then remaining nearly constant at high confinement. Compared with loading-cracked specimen, smaller critical axial strain, greater critical lateral strain, and higher lateral creep strain rate were found for unloading-cracked specimen. Based on the spatial and temporal distribution of acoustic emission events, the cracking process during creep was analysed. The AE events with high energy are mainly concentrated at the final fracture area of the specimen. The higher the confining pressure, the more the AE events with low energy. Compared with the loading-cracked specimen, the percentage of AE events with high energy is relatively small for the unloading-cracked specimen.
A New Model for Arabic Text Clustering by Word Embedding and Arabic Word Net

A major challenge in article clustering is high dimensionality, because this will affect directly to the accuracy. However, it is becoming more important due to the huge textual information available online. In this paper, we proposed an Arabic word net dictionary to extract, select and reduce the features. Additionally, we use the embedding Word2Vector model as feature weighting technique. Finally, for the clustering uses the hierarchy clustering. Our methods are using the Arabic word net dictionary with word embedding, additionally by using the discretization. This method are effective and can enhance improve the accuracy of clustering, which shown in our experimental results.
Effect of Levels of Awareness and Impact of HIV/AIDs among Christians in Meru South Sub County, Kenya

There is a general assumption that awareness of HIV/AIDs among the youth is high. However, the rate at which the youth in churches fall out due to unwanted pregnancies and infections confirm that young people are neither abstaining nor engaging in safe sex. This study investigated the impact of HIV/AIDs awareness on the sexual behavior among youth in selected churches in Meru South Sub County, Kenya. The study established that the youth have a lot of knowledge about HIV/AIDs. However, various external influences interfere with their change of sexual behavior. The study found that among the major factors that encourage sexual activity among the youth are sexual programme aired through the mass media, parental negligence, religious programmes that are irrelevant and do not address needs of the youth adequately, peer pressure and the internet. The study recommends that churches should demystify the impact of HIV/AIDs in the church since the church is an extension of the society and therefore a social institution.
Baby Measure Theory

All of probability theory can be divided into two parts. I call them master’s level and PhD level probability theory. Other terms are classical probability theory and measure-theoretic probability theory. Historically, the dividing line is 1933 when Grundbegriffe der Wahrscheinlichkeitsrechnung (Foundations of the Theory of Probability) by Andrey Kolmogorov was published (although Kolmogorov was Russian, he wrote in German to reach a wider audience). What Kolmogorov did was to say that the new real analysis that had started with the PhD thesis of Henri Lebesgue (1902) and had been rapidly generalized to integrals of real-valued functions on arbitrary spaces by Radon, Fréchet, and others (called Lebesgue integration or abstract integration) should also be used in probability theory.
A Case-Control Study On Risk Factors Of Breast Cancer Among Women Attending A Tertiary Care Hospital In Kolkata, India

Backgrounds: Breast cancer is the leading cancer in female globally. Incidence of breast cancer is also found increasing in developing countries like India owing to the rapid urbanization and life style changes. Presence of multiple risk factors with their varied risk estimates in different studies has made it difficult to design a specific primary prevention program. This study aimed at identifying various factors associated with breast cancer along with estimating their risk among women from an eastern state of India. Methods: This is a Hospital based age group matched case-control study in which 66 confirmed female breast cancer cases and 264 Swati Pramanick1, Debjit Chakraborty2,3*, Satyajit Bera1, Karabi Dutta4, Ramendra Narayan Chauduri5 and Ashok Chakraborty6* 1Directorate of Health Service, Government of West Bengal, West Bengal, India 2Integrated Disease Surveillance Program, State Surveillance Unit, West Bengal, India 3State Urban Development Agency, Government of West Bengal, West Bengal, India 4Chittaranjan National Cancer Institute, Kolkata, West Bengal, India 5All India Institute of Hygiene and Public Health, West Bengal, India 6Sacred Heart University, Fairfield, Connecticut, USA A Case-Control Study on Risk Factors of Breast Cancer among Women Attending a Tertiary Care Hospital in Kolkata, India female controls (1:4 ratios) were interviewed on various exposure status by a predesigned, pretested questionnaire. Univariate and multivariate techniques were used for the analysis of data and the risk was estimated in terms of Odds Ratio (OR) with 95% Confidence Interval (CI). Results: Nine factors (positive family history, place of residence, occupation, Body Mass Index, age of menarche, age of first delivery, duration of breastfeeding, exposure to chest X-ray and tobacco chewing) were found to be associated with breast cancer on univariate analysis. Out of them only four factors namely family history of breast cancer, exposure to chest X-Ray, exposure to chewing tobacco, and Body Mass Index ≥25, showed significant risk on multivariate analysis. Conclusion: This study identified significant risk with the factors relatively less reported like, exposure to chest X-ray, smokeless tobacco.
A sparse topic model for bursty topic discovery in social networks

Bursty topic discovery aims to automatically identify bursty events and continuously keep track of known events. The existing methods focus on the topic model. However, the sparsity of short text brings the challenge to the traditional topic models because the words are too few to learn from the original corpus. To tackle this problem, we propose a Sparse Topic Model (STM) for bursty topic discovery. First, we distinguish the modeling between the bursty topic and the common topic to detect the change of the words in time and discover the bursty words. Second, we introduce “Spike and Slab” prior to decouple the sparsity and smoothness of a distribution. The bursty words are leveraged to achieve automatic discovery of the bursty topics. Finally, to evaluate the effectiveness of our proposed algorithm, we collect Sina weibo dataset to conduct various experiments. Both qualitative and quantitative evaluations demonstrate that the proposed STM algorithm outperforms favorably against several state-of-the-art methods
The Competence of Language Skills: Listening, Speaking, Reading and Writing and Its Impact on the Performance of Kiswahili Literature among Secondary School Students in Wareng’ Sub County, Uasin Gishu County, Kenya

DOI: 10.21276/sjahss.2018. 6.3. 5 Abstract: This paper is based on a study of the competence of language skills and its impact on the performance of Kiswahili literature among form two and form four secondary school students in Wareng’ Sub county of Uasin Gishu County, Kenya. The author argues that for the students to perform well in Kiswahili literature, then they must have a high competence in language skills. This includes competence in listening, speaking, reading and writing. Once this is acquired or not, students will tend to have either a positive or a negative attitude which further would impact on the performance of literature in Kiswahili and the general performance of the Kiswahili subject. This paper uses the Pragmatic theory an approach whose main tenets states that practical approach to language skills is core in the foundation of competence in literature and language as a whole. The theory also postulates that students should be exposed to the language skills early in their education, so that as they progress from one level to the next, they will be able to build the necessary competence for good performance in their exams. The students were exposed to the practical literature excerpts where their interaction in usage of literature materials enabled the researcher to assess measure and record their competence in the language skills. The findings showed that the students had challenges in the language skills and that affected their performance in Kiswahili literature. This finding of this study makes recommendation that would mitigate the situation. First being the core importance of language in any society is communication. Secondly, knowledge generated will benefit students, teachers, scholars and the society in general, on the importance of competence in language skills, for communication and good performance among students.
Dose evaluation of radiosensitive organs during high-pitch third generation dual-source CT of the chest

Poster: "ECR 2018 / C-0944 / Dose evaluation of radiosensitive organs during high-pitch third generation dual-source CT of the chest " by: " K. Takegami 1, H. Hayashi2, S. Tokurei1, A. Hashimoto1, S. Kudomi3, T. Okazaki 4, T. Hashizume5; 1Yamaguchi/JP, 2Tokushima, Tokushima/JP, 3Yamaguchi-ken/JP, 4Tsukuba, Ibaraki/JP, 5Tsukuba/JP"
Lipid based systems for ocular drug delivery: Effect of surface modification

Significant challenges for pharmaceutical scientists still exist despite numerous technological advancements in the field, and the efficient ocular drug delivery remains elusive. Exclusive and exquisite barrier characteristics, unique physiology make the ocular milieu impervious to xenobiotics. Precorneal residence, mucoadhesion and transmembrane permeation needs to be improved using topical non-invasive strategies across ocular surface show promise for the intraocular delivery. Viable advantages such as higher drug loading, tailored drug release, biocompatibility and mucoadhesive properties can improve delivery of lipophilic drug using colloidal nanoparticulate frameworks. Lipid based systems comprise solid lipid nanoparticles (SLNs) and Nanostructured lipid carriers (NLCs). Nanoparticles are better internalized in ocular epithelial tissues by endocytosis/transcytosis mechanisms and diffuse rapidly owing to their nano size. Penetration and retention characteristics of ocular small molecule therapeutics can be dramatically improved by the surface functionalization of lipid nanoparticles. This review summarizes scientific results such as articles and patents that involve the potential application of lipid nanoparticles as platform for the ocular drug delivery.
Designing for Psychological Needs in Fitness Tracking: Supporting Engagement and Adherence

Wearable fitness trackers offer new opportunities for monitoring physical activity (PA) and reduce the risk of obesity. However, much work is needed to understand how to engage individuals in fitness tracking and how to support adherence to regular PA, especially in families and in low-socioeconomic status (SES) contexts. In this work, we synthesize our qualitative findings across two fitness tracking studies with 27 families of low-SES backgrounds. We found that the psychological needs of relatedness and competence were particularly salient during fitness tracking. We provide recommendations on how to support engagement and adherence by satisfying the users’ psychological needs.
HETEROLOGOUS PRODUCTION OF SYNTHETIC CATIONIC ANTIMICROBIAL PEPTIDE IN NOVEL OSMOTICALLY INDUCIBLE E.COLI GJ1158

Cationic antimicrobial peptides are the upcoming therapeutic molecules as alternative drugs to the antibiotics. These peptides have a good scope in current antibiotic research. In the present study E. coli strain GJ1158 host was chosen for the expression of gene for Insilco designed synthetic peptide, Using Modified M9 medium. Various trails were carried out to optimize the recombinant peptide production in modified M9 medium by following the Placket Burman model. The optimal media was chosen for further expression studies and the expressed antimicrobial peptide was purified using Immobilized Metal Affinity Chromatography (IMAC) system. The product was visualized on 16% Tricine SDS-PAGE. It was identified that 30% of the bacterial proteins as the recombinant protein. The expressed antimicrobial peptide was purified using Immobilized Metal Affinity Chromatography (IMAC) system. The antimicrobial activity of purified peptide using Top agar assay showed that the recombinant antimicrobial peptide has high antibacterial activity against both Gram-positive and -negative bacteria.
A cyberbullying study: Analysis of cyberbullying, comorbidities and coping mechanisms

MOTS CLÉS Cyberbullying ; Harcèlement ; Internet ; Adolescents ; Mécanismes d’adaptations Résumé Les nouvelles technologies de l’information et de la communication (NTIC) permettent un accès privilégié à l’information pour les jeunes et les adultes. Si elles représentent un nouveau moyen d’interaction sociale, elles sont également porteuses de nouvelles formes de violences, la cyber-intimidation et le cyber-harcèlement, qui apparaissent et peuvent avoir des conséquences psychologiques sur les victimes et engendrer des conséquences dramatiques. Objectif. — L’objectif de cette étude est donc d’évaluer la proportion de victimes de cyberbullying, sur un échantillon de jeunes français de 16 à 18 ans, d’une part, et chez les adultes, d’autre part, d’analyser les caractéristiques de la cyber-intimidation, de comprendre les différents facteurs susceptibles de diminuer ou amplifier cet effet d’intimidation et d’explorer les liens avec une comorbidité, anxieuse et dépressive. Nous nous intéresserons également aux mécanismes d’adaptation permettant à la victime de réagir différemment selon le contexte émotionnel et comportemental en utilisant une échelle innovante sur « la résilience ». Méthodologie. — Deux cent soixante-douze participants ont complété une batterie de questionnaires, contenant une échelle d’évaluation de l’anxiété sociale (LSAS), de l’anxiété et de la dépression (HAD), de l’aléxithymie (BVAQ), des réactions lors d’intenses émotions négatives (HDS) et de la résilience (BRS). Résultats. — Les analyses montrent que le phénomène du cyber-harcèlement était présent au sein de notre échantillon. Il y a eu 95 personnes sur un total de 272 (35 %) qui ont déclaré avoir été victimes d’au moins une forme de cyber-harcèlement (moyenne d’âge 17,8 ± 5,9 ans).
Securing Communications in the Internet of Things using ID-based Cryptography and Modern Elliptic Curves

The Internet of Things (IoT) is a fast evolving technology with many devices already available to end-users. However, the security of the IoT is less evolved. Current approaches either employ proprietary protocols, or use standard Internet protocols including the existing heavyweight and complex public-key infrastructure. In this thesis, we propose a security architecture built on identity-based cryptography that embeds of cryptographic information in IPv6 addresses, allowing end-to-end authentication of federated IoT networks. Our prototype using twisted Edwards curves allows deployment on constrained IoT devices. Our evaluation shows performance characteristics suitable for the scale and diversity of the IoT.
An Empirical Study of the Relationship between Leadership Styles and Organizational Performance using some selected Food and Beverage Firms in Nigeria

DOI: 10.21276/sjahss.2017. 5.9. 14 Abstract: This paper studied the relationship between leadership styles and organizational performance within selected food and beverage industry in Nigeria. Five firms: UAC Nigeria, Flour Mills of Nigeria Plc. , Cadbury Plc. , Seven-Up Bottling Company Plc. , and Unilever Plc. were considered as case studies. A well-structured questionnaire was used as data collection tool. Out of 240 questionnaires administered, 220 were filled and returned indicating that approximately 92% of the questionnaires administered were used for this study. Chi-squared test statistic as well as Coefficient of Contingency was used for data analysis; the computations were performed within the environment of R-statistical package. Having empirically established that leadership styles do not depend on organizational performance, the author was able to conclude that approximately 19% degree of association exists between leadership styles and organizational performance.
Financial management practices and performance of SMEs in Sri Lanka: evidence from Jaffna District

Efficient financial management practices is essential for small and medium enterprises to reach growth stage of the firm as it has major effect on performance. The aim of this study is to find out the financial management practices among small and medium sized enterprises in Jaffna district and also examine the impact of financial management practices on performance of SMEs. Financial management practices have been measured by working capital management, investment appraisal, capital structure management, financial reporting and analysis and accounting information system. Performance has been measured by perceptions on performance of owner of SMEs. Stratified random sampling method was used to select the participants from registered SMEs in Jaffna district. Data was collected through the self administered questionnaire from 60 SMEs functioning in Jaffna district. Descriptive and inferential statistics were used to analyze the data using SPSS. Cronbach's Alpha was used to check the reliability of the data. Results of the study revealed that there is a significant difference in the application of financial management practices between small and medium enterprises. Financial management practices of working capital management, investment appraisal, capital structure management, financial reporting and analysis and accounting information system are highly applied by medium sized enterprises than small enterprises. Working capital management and capital structure management have significant impact on SMEs performance. Outcome of the study may be useful to the practitioners to focus the financial management practices in order to enhance their business performance.