Miracle-dz/UniFAR-FTUs huggingface dataset:
Client perception of a client-centered and occupation-based intervention for at-risk youth

Abstract Background: A community-based occupational therapy program aims to provide client-centered and occupation-based interventions to at-risk youth. Objective: This pilot study explores how at-risk youth experiencing psychosocial and environmental barriers to occupation respond to client-centered and occupation-based occupational therapy in the community. Method: One-on-one semi-structured interviews were conducted with five youth participants receiving individual therapy interventions through a community-based occupational therapy program. The transcript data were analyzed qualitatively. Results: Three themes emerged: (i) client-centered and occupation-based OT interventions, (ii) the youths’ increased self-advocacy, and (iii) the enhancement of youths’ perception of their future. Conclusion and significance: The youth in this study described OT interventions exemplifying client-centered and occupation-based therapy, a non-prescriptive approach that validates the individual and may prove especially effective in serving the at-risk youth population.
A restricting condition on transient behavior of redox flow battery in phase space

Power storage systems are expected to contribute the stable power distribution under disturbances in power systems. Recently, power quality such as momentum voltage sag is a critical issue for power systems. For maintaining power quality, battery is inevitable and expected to quickly respond to the disturbances in the power systems. Redox Flow Battery (RFB) is one of the batteries which is capable to compensate the disturbance rapidly. The response of RFB is governed by the chemical, fluid and electrical dynamics with multiple time scales. The fast dynamics of external circuit has been neglected in the discussion of modeling. In this paper, we discuss the limitation of the transient behavior based on the phase space analysis with a previously proposed model. Here is, in particular, focused on the discussion of the parameters related to the flow of the electrolysis solution. As a result, it is clarified that the transient behavior is forcedly bound by the external electrical circuit at the load change, and the flow of the electrolysis solution pushed the increase of the consumption of ions down.
Feature article: onboard visual sense and avoid system for small aircraft

The sense and avoid (SAA) capability is a key issue in the integration of Unmanned Aircraft Systems (UAS) into the common airspace. Besides the lack of a regulatory framework in most countries, some technological challenges are still not resolved which holds back routine UAS applications. Most UAS or Remotely Piloted Aircraft Systems (RPAS) have no SAA capability. The separation for these aircrafts must be done solely by the Air Traffic Control (ATC) which is not cost effective. Furthermore, in the case of a lost link, there should be some kind of collision avoidance capability onboard; otherwise, if we want to maintain the current safety level of the air traffic system, a single unmanned airplane would block a significant sector of the airspace. Besides the safety and cost issues in the RPAS case, general aviation could benefit from a solid SAA system as well. An SAA instrument could support pilots in the case of conflicting instructions coming from the different layers of collision avoidance (for example ATC and onboard devices) and in some cases it could extend the range for the non-cooperative collision avoidance done by the pilots. An ideal SAA system would be cost effective, lightweight, and low-power in order to minimize the negative effect on cost, make application onboard small unmanned aerial vehicles (UAVs) possible, and maximize flight time of the aircraft.
Emergency Cervical Cerclage: A Retrospective Review of 51 Cases

Fifty-one patients underwent emergency cervical cerclage using Shirodkar or McDonald suture for incompetent cervix diagnosed during pregnancy. Fifteen patients had only sonographic evidence of cervical incompetence (group I). Eighteen patients had cervical dilation of less than 3 cm (group II), and 18 patients had cervical dilation of 3 cm or more (group III). Perinatal mortality was 0%, 50%, and 55.6%, respectively. The median length of time gained with the cerclage was 16 weeks in group I, 1.8 weeks in group II, and 1 week in group III. Twelve infants required prolonged stay in the neonatal intensive care nursery because of prematurity. Six of 30 surviving infants had some abnormal physical findings at the time of initial discharge from the nursery. Premature rupture of membranes was the most common perioperative and postoperative complication. Chorioamnionitis developed in 17 of the 51 cases. Maternal complications included cervicovaginal fistula, deep vein thrombophlebitis, and pulmonary edema.
Tempering Allorecognition to Induce Transplant Tolerance With Chemically Modified Apoptotic Donor Cells

The development of organ transplantation as a therapy for end‐stage organ failure is among the most significant achievements of 20th century medicine, but chronic rejection remains a barrier to achieving long‐term success. Current therapeutic regimens consist of immunosuppressive drugs that are efficient at delaying rejection but are associated with significant risks such as opportunistic infections, toxicity, and malignancy. Thus, the induction of specific immune tolerance to transplant antigens is the coveted aim of researchers. The use of 1‐ethyl‐3‐(3‐dimethylaminopropyl)carbodiimide (ECDI)‐treated, autoantigen‐coupled syngeneic leukocytes has been developed as a specific immunotherapy in preclinical models of autoimmunity and is currently in a phase II clinical trial for the treatment of multiple sclerosis. In this review, we discuss the use of allogeneic ECDI‐treated apoptotic donor leukocytes (allo‐ECDI‐SP) as a strategy for inducing antigen‐specific tolerance in allogeneic transplantation. Allo‐ECDI‐SP therapy induces long‐term systemic immune tolerance to transplant antigens by subverting alloimmune recognition and exploiting apoptotic cell uptake pathways to recapitulate innate mechanisms of peripheral tolerance. Lastly, we discuss potential indications and challenges for transitioning allo‐ECDI‐SP therapy into clinical practice.
Hexa(methoxymethyl)melamine: An Emerging Contaminant in German Rivers

Hexa(methoxymethyl)melamine (HMMM)‐containing resins are used in the production of coatings and plastics for cans, coils, and automobiles. A previous study demonstrated that this compound was associated with acute toxic effects on daphnia. This study presents the first compiled data on the occurrence of HMMM as an emerging contaminant in German rivers. The compound occurred in 60 of 117 water samples from three river systems, with concentrations ranging between <10 and 880 ng/L. Based on water concentrations and river flow on the day of sampling, the loads of HMMM were calculated for two rivers. The spatial distribution patterns of the loads showed large variations and did not follow clear trends along the stream course. These variations were attributed to effective removal processes, leading to sudden load decreases within short flow distances. The data suggest that HMMM could be discharged to the investigated rivers with wastewaters from the automotive industry and related branches.
Computation of the Lasserre Ranks of Some Polytopes

Over the years, various lift-and-project methods have been proposed to construct hierarchies of successive linear or semidefinite relaxations of a 0--1 polytope P ⊆ Rn that converge to P in n steps. Many such methods have been shown to require n steps in the worst case. In this paper, we show that the method of Lasserre also requires n steps in the worst case.
Mecanismos kaldorianos del crecimiento regional: Aplicación empírica al caso del ALADI (1980 - 2007)

According to Kaldor (1970), regional growth patterns arise from a cumulative causation process as broadly combining two substantial mechanisms i.e. a productivity regime, known as the “Kaldor-Verdoorn” law, and a demand regime due to the expansion of exportations. This paper attempts to assess empirically the Kaldor’s framework in characterizing economic growth for 11 ALADI countries from a panel data set over period 1980 to 2007. After having controlled industrial heterogeneity, the results are indicating the existence of two regional trends within member states, especially in terms of external demand constraint. It can be pointed out a group of countries for which the link between productivity gains and demand growth has become weaker, due to an increasing external dependence as well as a detrimental competitive position. Finally, findings are quite conclusive insofar as the existence of the Kaldorian mechanisms is corroborated in explaining trajectories of ALADI countries while both increasing returns to scale and demand led growth are seemingly playing a significant role in the region.
Antidepressants and neuroplasticity.

OBJECTIVE We review the literature on the cellular changes that underlie the structural impairments observed in brains of animals exposed to stress and in subjects with depressive disorders. We discuss the molecular, cellular and structural adaptations that underlie the therapeutic responses of different classes of antidepressants and contribute to the adaptive plasticity induced in the brain by these drugs. METHODS We review results from various clinical and basic research studies. RESULTS Studies demonstrate that chronic antidepressant treatment increases the rate of neurogenesis in the adult hippocampus. Studies also show that antidepressants up-regulate the cyclic adenosine monophosphate (cAMP) and the neurotrophin signaling pathways involved in plasticity and survival. In vitro and in vivo data provide direct evidence that the transcription factor, cAMP response element-binding protein (CREB) and the neurotrophin, brain derived-neurotrophic factor (BDNF) are key mediators of the therapeutic response to antidepressants. CONCLUSIONS These results suggest that depression maybe associated with a disruption of mechanisms that govern cell survival and neural plasticity in the brain. Antidepressants could mediate their effects by increasing neurogenesis and modulating the signaling pathways involved in plasticity and survival.
Substrate affects growth and yield of shiitake mushroom

Lentinus edodes (Berk.), the shiitake mushroom, is worldwide one of the most widely cultivated mushrooms. Sawdust is the most popular basal ingredient used in synthetic substrate formulations for producing shiitake spawn. However, the best sawdust for this uses needs to be determined. Shiitake mushroom was cultivated on sawdust from the woody plants Babla (Acacia nilotica L.), Champa (Michelia champaca L.), Garzon (Dipterocarpus alatus Roxb.), Ipil-ipil [Leucaena glauca (Linn) Benth], Jackfruit (Artocarpus heterophyllus Lam), Mango (Mangifera indica L.), Raintree [Albizia saman (Jacq.) F Mull], Segun (Tectona grandis L), Shimul (Bombax ceiba L), Shisoo (Dalbergia sissoo Roxb) or mixtures of sawdust from all of the trees with equal ratio or rice straw to determine growth and fruiting characteristics. Cultivation on Jackfruit resulted in significantly faster mycelial growth compared to other substrates. With respect to fructification, culture on Jackfruit produced the first pinhead (primordium) earlier compared to other substrates. Numbers of primordial and effective fruiting bodies was highest on Jackfruit sawdust. Rice straw, surprisingly, did not produce any fruiting bodies as well as showing no yield attributes. Yield attributes including stalk length, stalk diameter and diameter and thickness of the pileus were significantly higher on Jackfruit. The lowest biological and economic yields were found when culture was on Champa. Biological efficiency and biological yield, economic yield and dry yield at the first and final harvests were highest with culture on Jackfruit and its use is recommended in the production of shiitake mushroom in the tropics.
One-Year Clinical Study on Efficacy of Corneal Cross-Linking in Indian Children With Progressive Keratoconus

Purpose: The aim of this study was to assess the efficacy of corneal collagen cross-linking (CXL) with riboflavin using ultraviolet-A light in children with progressive keratoconus. Methods: Thirty-five eyes of 24 children with progressive keratoconus aged between 9 and 16 years were included in this retrospective study. Ocular examination included the best-corrected visual acuity (BCVA), dilated refraction, slit-lamp exam, and corneal topography (Orbscan II) at 6 and 12 months. All children were treated with riboflavin with ultraviolet-A light under topical anesthesia and all completed 1-year follow-up. Results: The mean age of the children was 13.65 years (range, 9–16 years). Follow-up was for a period of 1 year. The mean of preoperative keratometry (Kmax) was 55.11 ± 5.34 diopters (D), whereas the mean of postoperative Kmax was reduced to 53.87 ± 4.99 D. The mean preoperative pachymetry was 412.31 ± 36.54 &mgr;m, which changed to 361.31 ± 58.04 &mgr;m postoperatively. At 1 year, improvement in the BCVA was noted in 18 (51.42%) eyes, stabilization in 12 (34.28%), and worsening in 5 (14.28%) eyes. Overall, the BCVA improved by 1 line, which was statistically significant (P = 0.0368) at the end of 1 year. There was a reduction in both cylindrical and spherical equivalent, of which, the latter was not statistically significant (P = 0.77), whereas the former was of weak statistical significance (P = 0.061). No complications were reported. Conclusions: CXL with riboflavin is an effective procedure for children with progressive keratoconus. The results show stabilization, improvement, or both in keratoconus in terms of BCVA and corneal curvature after CXL in most children.
Sobre el Factor de Productividad del Aeropuerto Internacional Jorge Chávez (On the Productivity Factor of Jorge Chavez International Airport)

Spanish Abstract: El presente documento tiene como objetivo revisar y analizar, desde la perspectiva metodologica, las discrepancias en la revision tarifaria de la Concesion del Aeropuerto Internacional Jorge Chavez (AIJCH), entre la metodologia adoptada por Organismo Supervisor de la Inversion en Infraestructura de Transporte de uso publico (OSITRAN) y Lima Airport Partners (LAP) para la estimacion de Factor de Productividad (X). Adicionalmente, se realizara un recalculo de dicho factor bajo los criterios metodologicos. English Abstract: The present document aims to review and analyze, from the methodological perspective, the discrepancies in the tariff revision of the Jorge Chavez International Airport Concession (AIJCH), between the methodology adopted by Supervisory Body of Investment in Public Transport Infrastructure (OSITRAN) and Lima Airport Partners (LAP) for the estimation of Productivity Factor (X). In addition, a recalculation of this factor will be performed under the methodological criteria.
Comparison between Range-Difference-based and Bistatic-Range-based localization in multistatic passive radar

Two least square techniques, Bistatic-Range-based (BR-based) method and Range-Difference-based (RD-based) method, are presented to find the location of a target in multistatic passive radar. Also, the Cramer-Rao lower bound (CRLB) of the location estimates is obtained for both of them in this issue. For these two presented techniques, we see that the performance of the BR-based technique is quite better than the RD-based technique in the simulation results. For this reason, using the BR-based technique in multistatic passive radar is recommended. Furthermore, the BR-based method required one less receiver than the RD-based method for finding the target position uniquely. The simulation results also show that the placement is important to decrease the error of target position estimation.
Foreign direct investment in Southeast Asia

Foreign direct investment has been of great importance in economic growth and global economic integration over the last decades. South East Asia has been part of this development, with rapidly increasing inflows of FDI. However, there are large variations over time and between countries in the region with respect to policies towards FDI, and in actual inflows of FDI. This chapter aims to examine the size of FDI in South East Asia and trends in it. The main determinants of FDI in Southeast Asia, and their effect on the host countries are also discussed and examined. Handbook of Southeast Asian Economics, forthcoming
Fibroblast growth factor receptor 1 is a key inhibitor of TGFβ signaling in the endothelium

Endothelial-to-mesenchymal transition is suppressed by FGFR1 signaling. Strategies to Prevent Vascular Scarring The endothelium that lines blood vessels can undergo a change called endothelial-to-mesenchymal transition (EndMT). EndMT can cause vessel “scarring,” which limits the success of surgical procedures in which blood vessels are grafted onto each other, such as during heart transplantation or coronary bypass surgery. Chen et al. found that the fibroblast growth factor receptor 1 (FGFR1) signaling pathway in endothelial cells prevented EndMT. The researchers performed blood vessel grafting in mice lacking FGFR1 in endothelial cells and found that the vessels showed increased EndMT. Arteries from patients who had rejected heart transplants had less FGFR1 than those from normal individuals. Thus, enhancing FGFR1 activity could improve the outcome of patients with heart disease undergoing surgical procedures. Abnormal vascular homeostasis can lead to increased proliferation of smooth muscle cells and deposition of extracellular matrix, resulting in neointima formation, which contributes to vascular lumen narrowing, a pathology that underlies diseases including transplant vasculopathy, the recurrence of stenosis, and atherosclerosis. Growth of neointima is in part due to endothelial-to-mesenchymal transition (EndMT), a transforming growth factor–β (TGFβ)–driven process, which leads to increased numbers of smooth muscle cells and fibroblasts and deposition of extracellular matrix. We reported that endothelial cell–specific knockout of fibroblast growth factor receptor 1 (FGFR1) led to activation of TGFβ signaling and development of EndMT in vitro and in vivo. Furthermore, EndMT in human diseased vasculature correlated with decreased abundance of FGFR1. These findings identify FGFR1 as the key regulator of TGFβ signaling and EndMT development.
Molecular Insights Reveal Psy1, SGR, and SlMYB12 Genes are Associated with Diverse Fruit Color Pigments in Tomato (Solanum lycopersicum L.)

The color of tomato (Solanum lycopersicum) fruit flesh is often used as an indicator of quality. Generally, fruit color is determined by the accumulation of carotenoids and flavonoids, along with concomitant degradation of chlorophylls during ripening. Several genes, such as phytoenesynthetase1 (Psy1), STAY-GREEN (SGR), and SlMYB12, have been extensively studied to elucidate the genes controlling fruit coloration. In this study, we observed low carotenoid levels without degradation of chlorophylls in green-fruited tomato caused by mutations in three genes, Psy1, SGR, and SlMYB12. We crossed two inbred lines, BUC30 (green-fruited) and KNR3 (red-fruited), to confirm the causal effects of these mutations on fruit coloration. The F2 population segregated for eight different fruit colors in the proportions expected for three pairs of gene, as confirmed by a chi-square test. Therefore, we developed a population of tomato with diverse fruit colors and used molecular markers to detect the genes responsible for the individual fruit colors. These newly-designed DNA-based markers can be used for selecting desired fruit color genotypes within adapted breeding materials and cultivars for breeding.
Changes in physical activity patterns in the United States, by sex and cross-sectional age.

PURPOSE To determine sex-specific, age-related changes in physical activity patterns. METHODS We examined cross-sectional data from the National Health Interview Survey, using the 1992 Youth Risk Behavior Survey supplement for adolescents and the 1991 Health Promotion/Disease Prevention supplement for adults. Physical activity patterns were modeled after Healthy People 2000 objectives. RESULTS Among adolescents, physical activity patterns generally eroded most from ages 15 through 18. The "regular, vigorous activity" and strengthening patterns declined consistently from ages 12 through 21. Young adulthood (18-29 yr) often marked continuing erosion of activity patterns, whereas middle adulthood (30-64 yr) often revealed relatively stable patterns. At retirement age (65 yr), there was a stabilizing, or even an improving, tendency in activity patterns, usually followed by further erosion through the final period of life. Strengthening behavior eroded dramatically with advancing age among adults, especially among men. Among adolescents, differences between female and male respondents were large for regular, vigorous activity (11.3 percentage points greater for male respondents). In comparison with female adolescents and adults, male respondents reported much higher rates of regular, sustained activity (5.5 and 5.9 percentage points, respectively), and strengthening (18.2 and 11.3 percentage points, respectively). Among adults, levels of physical inactivity among women were moderately greater (5.5 percentage points) than for men. Absolute rates of change per year were mostly large to very large (3.0-8.0 percentage points x yr(-1)) during ages 15-18 yr, but, for adults, they were small (<0.5 percentage points x yr(-1)) for 33 of 40 sex, age, and pattern groupings. CONCLUSION These data suggest that early and continued intervention will be necessary to offset these declines in physical activity throughout adolescence and adulthood.
High speed LVDS driver for SERDES

Low Voltage Differential Signaling (LVDS) is a method used for high-speed transmission of binary data over copper cable. In the earlier remote sensing payload camera electronics, the multi-port parallel data were provided to spacecraft base-band system, requiring large number of I/O connectors and associated harnesses. This multi-port parallel data can be multiplexed, serialized and transmitted to other subsystems using LVDS interface thereby reducing the number of I/Os, cabling and associated weight of interface hardware. This work presents the design, simulation and analysis of I/O interface circuits for high speed operation which is fully compliant with the IEEE STD 1596.3 (LVDS). A common mode feedback (CMFB) circuitry is utilized in the LVDS transmitter to stabilize the common mode voltage in a pre-defined range. In most of the previous designs [1] output cells utilize voltage divider circuit composed of two large resistors (≈MΩ) between output pads and center is taped as feedback. These resistors may be off-chip discrete components (due to stringent stability and large die area requirement). The modified common mode feedback circuit has been designed and analyzed with appropriate transistor geometry and evaluated. Its performance is also compared with conventional CMFB design.