Miracle-dz/UniFAR-FTUs huggingface dataset:
Title Effects of fluorine incorporation on the electrical properties ofsilicon MOS capacitor with La 2 O 3 gate dielectric

In this work, the effects of fluorine incorporation by using plasma on the electrical properties of Si MOS capacitor with La2O3 gate dielectric are investigated. From the capacitance-voltage (C-V) curve and gate leakage current, it is demonstrated that the F-plasma treatment can effectively suppress the growth of interfacial layer, and thus improve the electrical properties of the device in terms of accumulation capacitance, interface-state density and breakdown voltage. Index Terms — fluorine, high-k dielectric, interfacial layer , lanthanum oxide, MOS.
Strain Characterization of InAs Segment in Au-free InP/InAs Heterostructure Nanowires by Micro-Raman Measurement

Heterostructure nanowire with large lattice mismatch provides new opportunities in making use of strain engineering tool and developing new functional devices. Therefore, it becomes necessary to characterize the strain and understand the lattice deformation mechanism in the nanowire structure. Here, we report the strain characterization of InAs segment in Au-free InP/InAs heterostructure nanowires by performing micro-Raman measurement in the single nanowire level. We revealed that there is compressive strain in InAs segment and the strain increases with the diameter but decreases with the segment thickness.
Financial Valuation and Risk Management Working Paper No . 352 House Prices , Real Estate Returns and the Business Cycle

The main objective of this work is to develop a general equilibrium business cycle model linking financial and real estate markets to the macroeconomy. The ability of a production economy to account simultaneously for asset pricing, business cycle and real estate market facts is then evaluated by comparing the model predictions to the empirical facts. The observed high volatility of house prices, the equity premium and the difference between equity and real estate excess returns can be explained without giving rise to excessive risk-free rate variation. •
Behavioral and biochemical effects of Cannabis Sativa and their modulation by antidepressant drugs

We aimed to study the effect of Cannabis sativa on brain oxidative stress and determine whether behavioral responses caused by cannabis could be reversed by standard antidepressant drugs. Cannabis sativa (5, 10 or 15 mg/kg) (expressed as D9-tetrahydrocannabinol) was given alone or with fluoxetine, sertraline or imipramine, once daily subcutaneously (s.c.) for 24 days. In the forced-swimming test, the immobility time, was significantly increased in mice treated with cannabis (5-15 mg/kg, s.c.) starting from the 9th day post-injection. Fluoxetine (20 mg/kg, s.c.) coadministered with cannabis (5 mg/kg, s.c.) resulted in significant decrease in the immobility time by the day 21 of the study compared with the cannabis only group. Mice co-administered sertraline or imipramine with cannabis were not statistically different from the vehicle control group as regards their immobility time. Cannabis resulted in a significant decrease in the rearing activity which was ameliorated by either fluoxetine or sertraline. Cannabis sativa increased brain reduced glutathione, but decreased the level of nitric oxide. Fluoxetine, sertraline or imipramine given with cannabis decreased malondialdehyde and increased reduced glutathione. In conclusion: The administration of cannabis decreases brain oxidative stress but exerts depressive-like effect and decreases rearing activity which can be reversed by antidepressant drugs. www.relaquim. com
UvA-DARE ( Digital Academic Repository ) Complex polar machinery required for proper chromosome segregation in vegetative and sporulating cells of Bacillus subtilis Kloosterman

Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: http://uba.uva. nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.
Leadership models and behaviors for sales executives. What drives success and the best results?

Abstract The paper analyses the effectiveness of the best leadership models and behaviours that are used by sales executives. Although, the impact of the most common characteristics and behaviours used in sales have been researched very well, recent research has only very limited results on a comparison of the most successful leadership personality traits and behaviours depending on companies’ situation and the context. In this paper we analyse two different situations: dynamic environment and stable environment. The context in this paper refers to the area sales. The paper will provide an explanation of the most successful leadership style used in sales and the characteristics of it and why they are also very useful in a sales process. Additionally, we will analyse the effectiveness of these characteristics in the two different situations of a company and exclusively in the sales context. We argue that the characteristics can be defined as the most effective one in every situation and context. We will develop a theoretical overview that shows clearly the best leadership traits and behaviours for each of the two situations in sales that is based on a literature research. The theoretical frameworks will be adjusted and confirmed with three senior sales executives from three different industries. The results of this paper will provide sales executives useful and easy to understand information about the advantages and disadvantages of the different leadership traits and behaviours depending on the context in and situation.
TEMPO-Oxidized Cellulose with High Degree of Oxidation

In this paper, water-soluble 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)-oxidized cellulose with a high degree of oxidation was prepared by a two-step process using bamboo dissolving pulp. The first step was to destroy the cellulose crystal I by NaOH/urea solution to obtain cellulose powder with decreased crystallinity. The second step was to oxidize the cellulose powder by TEMPO oxidation. The TEMPO-oxidized cellulose was analyzed by Fourier transform infrared spectroscopy (FTIR), conductimetry, X-ray diffraction (XRD), fiber analyzer, and transmission electron microscopy (TEM). FTIR showed that the hydroxymethyl groups in cellulose chains were converted into carboxyl groups. The degree of oxidation measured by conductimetry titration was as high as 91.0%. The TEMPO-oxidized cellulose was soluble in water for valuable polyelectrolytes and intermediates.
An Automatic Tree Skeleton Extracting Method Based on Point Cloud of Terrestrial Laser Scanner

Tree skeleton could describe the shape and topological structure of a tree, which are useful to forest researchers. Terrestrial laser scanner (TLS) can scan trees with high accuracy and speed to acquire the point cloud data, which could be used to extract tree skeletons. An adaptive extracting method of tree skeleton based on the point cloud data of TLS was proposed in this paper. The point cloud data were segmented by artificial filtration and -means clustering, and the point cloud data of trunk and branches remained to extract skeleton. Then the skeleton nodes were calculated by using breadth first search (BFS) method, quantifying method, and clustering method. Based on their connectivity, the skeleton nodes were connected to generate the tree skeleton, which would be smoothed by using Laplace smoothing method. In this paper, the point cloud data of a toona tree and peach tree were used to test the proposed method and for comparing the proposed method with the shortest path method to illustrate the robustness and superiority of the method. The experimental results showed that the shape of tree skeleton extracted was consistent with the real tree, which showed the method proposed in the paper is effective and feasible.
Molecular Cell Dcp 2 and Nudt 16 in mRNA Decapping mammalian

Regulation of RNA degradation plays an important role in the control of gene expression. One mechanism of eukaryotic mRNA decay proceeds through an initial deadenylation followed by 50 end decapping and exonucleolytic decay. Dcp2 is currently believed to be the only cytoplasmic decapping enzyme responsible for decapping of all mRNAs. Here we report that Dcp2 protein modestly contributes to bulk mRNA decay and surprisingly is not detectable in a subset of mouse and human tissues. Consistent with these findings, a hypomorphic knockout of Dcp2 had no adverse consequences in mice. In contrast, the previously reported Xenopus nucleolar decapping enzyme, Nudt16, is an ubiquitous cytoplasmic decapping enzyme in mammalian cells. Like Dcp2, Nudt16 also regulates the stability of a subset of mRNAs including a member of the motin family of proteins involved in angiogenesis, Angiomotin-like 2. These data demonstrate mammalian cells possess multiple mRNA decapping enzymes, including Nudt16 to regulate mRNA turnover.
Study on covert networks of terrorists based on interactive relationship hypothesis

Rapid development of social network theory provides new perspective for the study of behavior of terrorist organizations. Due to the covertness of terrorist activities, the absence of individuals and relationships often occurs in the construction of interpersonal relationship network of terrorists using social network theory, thus affecting the effectiveness of analysis. This paper proposes a method for constructing covert terrorist networks based on interactive relationship records and combining hypothesis and inference, and carries out empirical study combining typical terrorist activities within the borders. Study results show that key figures and missing figures obtained according to analysis and evaluation of constructed networks are consistent with reality. This shows that the combination of hypothesis and inference and interpersonal relationship records is a feasible way to improve the construction of terrorist social network model.
Actin-based stress fiber formation is coupled to microtubule depolymerization through the local activation of RhoA

David Meiri,1 Christopher B. Marshall,1,2 Melissa A. Greeve,1 Bryan Kim,1 Marc Balan,1,2 Fernando Suarez,1 Chris Bakal,1 Chuanjin Wu,1 Jose LaRose,1 Noah Fine,1,2 Mitsuhiko Ikura,1,2,* and Robert Rottapel1,2,3,4,* 1Ontario Cancer Institute and the Campbell Family Cancer Research Institute, 101 College Street, Room 8-703 Toronto Medical Discovery Tower, University of Toronto, Toronto, ON M5G 1L7, Canada 2Department of Medical Biophysics 3Departments of Medicine and Immunology University of Toronto, 1 King’s College Circle, Toronto, ON M5S 1A8, Canada 4Division of Rheumatology, St. Michael’s Hospital, 30 Bond Street, Toronto, ON M5B 1W8, Canada *Correspondence: mikura@uhnresearch.ca (M.I.), rottapel@uhnresearch.ca (R.R.) DOI 10.1016/j.molcel. 2012.01. 027
Molecular Cell Article CentromereTetheringConfinesChromosomeDomains

Jolien Suzanne Verdaasdonk,1 Paula Andrea Vasquez,3 Raymond Mario Barry,1 Timothy Barry,1 Scott Goodwin,1 M. Gregory Forest,2 and Kerry Bloom1,* 1Department of Biology 2Department of Mathematics and Biomedical Engineering University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 3Department of Mathematics, University of South Carolina, Columbia, SC 29208, USA *Correspondence: kerry_bloom@unc.edu http://dx.doi. org/10.1016/j.molcel. 2013.10. 021
Identifying Unknown Locations and Demography based Sentiment Analysis

Big Data Analytics in Geo-Spatial metadata is geographically annotated social media is extremely valuable for modern information retrieval. However, when researchers can only access publicly-visible data, one quickly finds that social media users rarely publish location information. In this work, we provide a method which can geo-locate the over whelming majority of active Social media users, independent of their location sharing preferences, using only publicly-visible user data. My method infers an unknown user's location by examining their friend's locations. We frame the problem of identifying the location and optimization over a social network with a total variation based objective and provide a scalable and distributed algorithm for its solution. Furthermore, we show how a robust estimate of the geographic dispersion of each user's ego network can be used as a per-user accuracy measure, allowing us to discard poor location inferences and control the overall error of our approach and finally the sentimental analysis of the obtained user's data over social media with user history statistics.
Some aspects in early life stage of snake head fish, Channa striatus larvae

The sexual maturity of female snake head fish, Channa striatus was studied by determining fecundity and gonadosomatic index (GSI). It was found that the size at sexual maturity of female snake head fish was 26.45±3.07 cm (mean ± SD, n=10) in total length and 167.4±48.09 g in body weight. The eggs were floating and rounded. The fertilized eggs had a diameter of 588±20.43 m. The fecundity was 10,279.1±2,527.9 ova/fish and gonadosomatic index (GSI) was 5.07±1.04 %. Newly hatched larvae of snake head fish were produced by induced spawning using chemical injection (Suprefact and Motilium). The sexually mature fishes were cultured in a fiber-glass tank (water volume 300 liters) with the ratio of male and female brooders 1:1. The fertilization rate, hatching out and hatching rate experiments were carried out using 3 15-liter glass aquaria (water volume 10 liters) each containing 1,000 eggs. It was found that the average fertilization rate was 76.50%, hatching out occurred of 28 hr 40 min and average hatching rate was 60.26 % at a water temperature of 26.5-29.0°C. Sampling of the newly-hatched larvae was done at 2-hour intervals, when 20 of them were randomly taken and preserved in 10% buffered formalin for later determination of yolk absorption time. Observation using a microscope revealed that newly hatched larvae were 3.18±0.11 mm in total length and had yolk sacs of 1,279.71±196.10 m 3 in volume. The yolk sacs were completely absorbed within 80 hr after hatching at a water temperature of 26.5-29.0°C. Up until full mouth development (start of feeding), 2-hourly samplings of twenty newly hatched larvae were taken from an aquarium for observation of the size of mouth opening. All the larvae had open mouths about 52 hr after hatching (5.48±0.16 mm TL), and measured 324.30±144.60 m in mouth opening. The feeding experiments were carried out using a 15-liter glass aquarium (water volume 10 liters) containing 1,000 larvae aged 1.5 days post-hatching (just before the mouth opened). They were fed with Moina at a density of 10 individual/ ml. Twenty larvae were collected at random from the aquarium at 2-hourly intervals, preserved in 10 % buffered formalin, and then dissected to determine the presence of Moina in the digestive tract. The digestive tracts were fixed at 62 hr of hatching at water temperatures of 28.0-30.5°C, and measured 334.87±149.78 m in mouth opening. The average number of Moina in the digestive tract at the start of feeding was 0.56 individual/larva.
Regulation of the DNA Damage Response and Gene Expression by the Dot1L Histone Methyltransferase and the 53Bp1 Tumour Suppressor

Background Dot1L, a histone methyltransferase that targets histone H3 lysine 79 (H3K79), has been implicated in gene regulation and the DNA damage response although its functions in these processes remain poorly defined. Methodology/Principal Findings Using the chicken DT40 model system, we generated cells in which the Dot1L gene is disrupted to examine the function and focal recruitment of the 53Bp1 DNA damage response protein. Detailed kinetic and dose response assays demonstrate that, despite the absence of H3K79 methylation demonstrated by mass spectrometry, 53Bp1 focal recruitment is not compromised in these cells. We also describe, for the first time, the phenotypes of a cell line lacking both Dot1L and 53Bp1. Dot1L−/− and wild type cells are equally resistant to ionising radiation, whereas 53Bp1−/−/Dot1L−/− cells display a striking DNA damage resistance phenotype. Dot1L and 53Bp1 also affect the expression of many genes. Loss of Dot1L activity dramatically alters the mRNA levels of over 1200 genes involved in diverse biological functions. These results, combined with the previously reported list of differentially expressed genes in mouse ES cells knocked down for Dot1L, demonstrates surprising cell type and species conservation of Dot1L-dependent gene expression. In 53Bp1−/− cells, over 300 genes, many with functions in immune responses and apoptosis, were differentially expressed. To date, this is the first global analysis of gene expression in a 53Bp1-deficient cell line. Conclusions/Significance Taken together, our results uncover a negative role for Dot1L and H3K79 methylation in the DNA damage response in the absence of 53Bp1. They also enlighten the roles of Dot1L and 53Bp1 in gene expression and the control of DNA double-strand repair pathways in the context of chromatin.
DEPOCEN Working Paper Series No . 2012 / 3 Housing Investment : What Makes It so Volatile ? Theory and Evidence from OECD Countries *

This paper explains how mortgage market liberalization can introduce greater volatility in the housing market, which is a stylized fact documented from OECD countries, with a DSGE model where households face a credit constraint and housing is used as collateral. The housing collateral constraint creates a link between the housing market and borrowing capacity, a link that amplifies the response of housing demand to technology shocks and strengthens in economies with more liberalized mortgage markets. The calibrated model is able to explain about 90 percent of housing investment volatility in the UK. JEL Classification: E22, E32, F34, F41
Title Page : Targeting GM-CSF in epithelial and vascular remodeling in experimental Eosinophilic Esophagitis ( 96 / 100 characters )

Background: Eosinophilic esophagitis (EoE) is a chronic antigen-mediated clinicopathologic disease of the esophagus characterized by an eosinophil-predominant inflammatory infiltrate. A clinical hallmark is extensive tissue remodeling including basal zone hyperplasia, fibrosis and angiogenesis. However, the cellular mechanisms responsible for these processes are not fully defined. We hypothesized that targeting GM-CSF (an agonist cytokine linked with eosinophil survival and activation) would be protective in a pre-clinical model of EoE. Methods: EoE-like esophageal inflammation was induced in the L2-IL5 EoE mouse model and GM-CSF production was assessed by mRNA and protein analyses. GM-CSFreceptor-alpha expression patterns were examined by flow cytometric and immunofluorescence analysis. L2-IL5 EoE mice were treated with anti-GM-CSF neutralizing antibody or isotype control and assessed for histopathological indices of eosinophilia, epithelial hyperplasia and angiogenesis by immunohistochemistry and RTPCR. Results: Significantly increased levels of esophageal GM-CSF expression was detected in the L2-IL5 mouse EoE model during active inflammation. GM-CSF-receptor-alpha was predominantly expressed on esophageal eosinophils during EoE, in addition to select cells within the lamina propria. Anti-GM-CSF neutralization in L2-IL5 EoE mice resulted in a significant diminution of epithelial eosinophilia in addition to basal cell hyperplasia and vascular remodeling. This treatment response was independent of effects on esophageal eosinophil maturation or activation. Conclusion: GM-CSF is a potential therapeutic target to reduce esophageal eosinophilia
Molecular Cell Perspective ‘ ‘ Cat ’ s Cradling ’ ’ the 3 D Genome by the Act of LncRNA Transcription

There is growing evidence that transcription and nuclear organization are tightly linked. Yet, whether transcription of thousands of long noncodingRNAs (lncRNAs) could play a role in this packaging process remains elusive. Although some lncRNAs have been found to have clear roles in nuclear architecture (e.g., FIRRE, NEAT1, XIST, and others), the vast majority remain poorly understood. In this Perspective, we highlight how the act of transcription can affect nuclear architecture. We synthesize several recent findings into a proposedmodel where the transcription of lncRNAs can serve as guide-posts for shaping genome organization. Thismodel is similar to the game ‘‘cat’s cradle,’’ where the shape of a string is successively changed by opening up new sites for finger placement. Analogously, transcription of lncRNAs could serve as ‘‘grip holds’’ for nuclear proteins to pull the genome into new positions. This model could explain general lncRNA properties such as low abundance and tissue specificity. Overall, we propose a general framework for how the act of lncRNA transcription could play a role in organizing the 3D genome.
China’s Food Security Evaluation Based on Factor Analysis

China’s food security has been a hot issue of social concern. Based on existing studies, this paper chose 12 factors to establish comprehensive evaluation system of good security, including the arable land area per capital, the fluctuation rate of grain yield, the grain price rising rate, the degree of agricultural mechanization, etc. Comprehensive evaluation of China’s food security over the years by factor analysis shows that China’s food security is in a tense balance state, the sources of which are the supportability factor slowdown and the score of stability factor decrease. Base on the analysis, we proposed to strengthen financial support to agriculture, improve the land protection mechanism, and improve the utilization rate of grain and other countermeasures to ensure China’s food security in the future.
MODERN DISTRIBUTION PATTERNS OF SNAILS AND PLANTS IN THE WESTERN CARPATHIAN SPRING FENS: IS IT A RESULT OF HISTORICAL DEVELOPMENT?

The aims of the study were: (1) to investigate the modern distribution pattern of snails in the Western Carpathians (Czech Republic and Slovakia) and compare it with the modern distribution pattern of plants, in which a conspicuous species turnover occurs on the scale of only tens of kilometres; and (2) to construct an hypothesis explaining why such a steep geographical gradient exists in such a small area, which is homogenous with respect to water chemistry and climate. Snail assemblages of 111 treeless base-rich spring-fen sites were sampled quantitatively from a homogeneous area of 16 m 2 (one sample of 12 l volume) in which a vegetation relevewas also recorded. The result of a partial detrended correspondence analysis of snail data with water pH and conductivity as co-variables confirmed clear differences between snail assemblages of the study area's western and eastern region. The regions differed in their species pool and the frequencies of particular species. In the eastern region, fen specialists and relics occurred and they were fairly frequent and abundant (e.g. Vertigo geyeri and Pupilla alpicola ). The western region differed by its higher frequency and abundance of woodland and ubiquitous species. The classification of snail species based on their co-occurrence with plant species reflected the known geographical pattern as well. We found that Western Carpathian fen vegetation as well as the fens' snail assemblages display a clear geographical gradient within a rather small area, independently of any climate or other environmental variation. Previously published palaeoecological data and both species composition and structure of modern assemblages suggest clear differences in the historical development of the two principal regions. Historical development seems to be one of the most important variables constituting qualitative characters of modern fragmented commu- nities. On a small scale it can influence especially organisms with slower migration rates, such as molluscs.