Miracle-dz/UniFAR-FTUs huggingface dataset:
Small heat shock proteins: Simplicity meets complexity

Small heat shock proteins (sHsps) are a ubiquitous and ancient family of ATP-independent molecular chaperones. A key characteristic of sHsps is that they exist in ensembles of iso-energetic oligomeric species differing in size. This property arises from a unique mode of assembly involving several parts of the subunits in a flexible manner. Current evidence suggests that smaller oligomers are more active chaperones. Thus, a shift in the equilibrium of the sHsp ensemble allows regulating the chaperone activity. Different mechanisms have been identified that reversibly change the oligomer equilibrium. The promiscuous interaction with non-native proteins generates complexes that can form aggregate-like structures from which native proteins are restored by ATP-dependent chaperones such as Hsp70 family members. In recent years, this basic paradigm has been expanded, and new roles and new cofactors, as well as variations in structure and regulation of sHsps, have emerged.
SEÇİLİ MENA ÜLKELERİNDE DOĞALGAZ TÜKETİMİ VE İKTİSADİ BÜYÜME ARASINDAKİ İLİŞKİ

Calismada dogalgaz tuketimi ile iktisadi buyume arasindaki uzun donemli iliski incelenmektedir. Bu iliskinin tanimlanmasi, uygun surdurulebilir buyume politikalarinin belirlenmesinde buyuk oneme sahiptir. Bu amacla 8 MENA ulke panel verisi kullanarak 1989-2014 donemi icin dogalgaz tuketimi ve iktisadi buyume arasindaki uzun donemli iliski arastirilmaktadir. Ekonometrik analizler sonucunda, dogalgaz tuketimi ile ekonomik buyume arasinda esbutunlesme iliskisinin varligina ve istatistiki olarak anlamli uzun donem katsayilarina ulasilmistir. Uzun donemli katsayilar, dogalgaz tuketiminin ekonomik buyumeyi pozitif etkiledigini gostermektedir.
The Practice of International Health: A Case-Based Orientation

Perlman D, Roy A, eds. 288 pages. New York: Oxford Univ Pr; 2009. $59.50. ISBN 9780195310276. Order at www.oup. com/us. Field of medicine: Global medicine, disaster relief, public health, medical anthropology, social medicine, women's studies, and gender politics. Audience: Clinicians; public and global health practitioners; medical, nursing, and public health students; humanitarian relief workers, medical missionaries, and anthropologists; Peace Corps volunteers; and gender and health equity advocates. Purpose: To provide insights into global health practices through personal, place-based narratives describing formative experiences for individuals who have contributed uniquely to global health. Content: A superb forward by Dr. Paul Farmer is complemented by introductions to each section by the editors that bring together the central themes of persons working on the front lines in global health. Chapters are narrative accounts of these individuals, divided into 3 major topic areas: Health and Development, The Difference That Gender Makes, and The Calculus of Health: Markets, Frontiers, Franchises. Highlights: Each chapter engages the reader as would a clinical case narrative from an experienced physician. These play out in many contexts: from an Eritrean physician and freedom fighter learning his own biases from the pastoralist society he serves, to the evolution of the paramedic and traditional birth attendant models in Bangladesh before they were adopted in the West, to the unraveling of a noninfectious neurologic syndrome originating from cassava-associated cyanide poisoning. Most challenging are the narratives dealing with disparities in women's health, rape, lethal abortions, honor crimes against women, women's empowerment, and the role of caste in limiting women's access to education and health. Limitations: None. Commentary: Having always valued a good patient history and outcome, I could not put this book down until I completed each narrative, often more than once. This book takes what are often dry numbers and statistics and breathes the life of story into each scenario. If there just were 1 book to read before beginning medical school, heading off for the Peace Corps, or starting that first semester of public health courses, this book must be it. Related reading: Kidder's Mountains Beyond Mountains (Random House, 2003) and Fadiman's The Spirit Catches You and You Fall Down (Farrar, Straus and Giroux, 2002). Reviewer: Frank J. Bia, MD, MPH, Yale School of Medicine, New Haven, and AmeriCares Foundation, Stamford, Connecticut.
h-index of geology journals: A statistical analysis based on scimago journal and country ranking

The study is based on geology journals that are covered in the database of SCImago Journal and Country Ranking database for the year 2015. Statistical Package for the Social Sciences (SPSS) is used for statistical computing. This study reveals that there is significant difference between open access and subscription based access journals in geology with regard to h-index. There is also a strong positive correlation among various factors of the journals in geology. It also predicts appropriate regression approach for calculating h-index based on relevant predictor variables. The study is limited by covering journals in geology subject field only from the SCImago Journal and Country Ranking for the year 2015. The valued article contributions in geology subject can be attracted by the journals having high h-index.
β-Neuregulin and Autocrine Mediated Survival of Schwann Cells Requires Activity of Ets Family Transcription Factors

Members of the Ets transcription factor family function in many biological processes. We show the presence of Ets transcription factors, most prominently Net, in neonatal rat Schwann cells, and demonstrate Ets-dependent transcription under conditions where the cells are exposed to autocrine signals or autocrine signals plus beta-neuregulin. Using the potent MAPK kinase inhibitor U0126 we also confirm that the MAP kinase pathway, an activator of Ets transcription, is involved in beta-neuregulin mediated Schwann cell survival. Furthermore, we find that expression of dominant negative Ets1 (N70-Ets1) inhibits both the beta-neuregulin and autocrine survival of Schwann cells. In contrast, the survival of Schwann cells mediated by lysophosphatidic acid (LPA) is unaffected by expression of a dominant negative Ets molecule. These data demonstrate that distinct autocrine and beta-neuregulin survival signals converge in their requirement for Ets dependent transcription in Schwann cell survival.
Introducing Values of Local Cultural Through Batik Motifs as The Identity of Surabaya City

The recognition of UNESCO towards batik as Indonesia's cultural heritage makes batik industries grow rapidly. Batik is currently used by the local government as a political media in introducing excellence and as an image of the region through the visual display of a particular icon that it symbolized. This research took place in Surabaya city as the location of observation. This study uses the approach of cultural studies and theories of semiotics as the main theory. The research results are expected to be used as educational media to introduce to the next generation to know the local values and the identity of the city of Surabaya. This is because the icon made on batik motif is a form of depiction of local art, historic buildings, special foods, until the flora and fauna typical Surabaya city. The results showed that the creation of batik motifs cannot be separated from the role of local government that seeks to create batik motifs according to regional identity. Batik characteristic of Surabaya has represented regional identity based on the concept of creation and meaning of batik itself, viewed based on motif, technique, color and composition. Keywords— local cultural values, batik motifs
Norepinephrine, the β-Adrenergic Receptor, and Immunity

Over the past 20 years, a significant effort has been made to define a role for the neuroendocrine system in the regulation of immunity. It was expected that these experimental findings would help to establish a strategy for the development of clinical interventions to either suppress or augment immunological function for disease prevention. However, the translation of these basic experimental findings into clinical interventions has been difficult. Possible explanations for this difficulty are that the findings from human and animal studies do not agree and/or that the results obtained within one species are rarely verified in the other. Our goal in writing this review is to address this issue by summarizing the published findings from human studies and comparing them to published findings from animal studies. Although far from being exhaustive, this review summarizes and discusses at least the past 10 years of findings in which a change in immunity and a change in catecholamine levels and/or stimulation of the β2-adrenergic receptor has been documented.
Heteroatom Substitution at Amide Nitrogen—Resonance Reduction and HERON Reactions of Anomeric Amides

This review describes how resonance in amides is greatly affected upon substitution at nitrogen by two electronegative atoms. Nitrogen becomes strongly pyramidal and resonance stabilisation, evaluated computationally, can be reduced to as little as 50% that of N,N-dimethylacetamide. However, this occurs without significant twisting about the amide bond, which is borne out both experimentally and theoretically. In certain configurations, reduced resonance and pronounced anomeric effects between heteroatom substituents are instrumental in driving the HERON (Heteroatom Rearrangement On Nitrogen) reaction, in which the more electronegative atom migrates from nitrogen to the carbonyl carbon in concert with heterolysis of the amide bond, to generate acyl derivatives and heteroatom-substituted nitrenes. In other cases the anomeric effect facilitates SN1 and SN2 reactivity at the amide nitrogen.
Benefits Obtained by Participation in, and Organization of, Interlaboratory Comparisons

Abstract: Laboratories continually strive to ensure the quality of instruments, procedures, and capabilities. No matter how carefully they conduct these internal checks, systematic deviations often go unnoticed. It is therefore important that they regularly compare their measurement results with those of other laboratories (benchmarking). Participation in interlaboratory comparisons is a vital investment in reliability, operational certitude, and staff confidence. NMi Van Swinden Laboratory (NMi VSL), the Dutch national institute for metrology, has more than 30 years of experience in interlaboratory comparisons. NMi VSL is accredited to organize interlaboratory comparisons. Highlighted will be 12.5 years of yearly comparisons between NIST (USA) and NMi VSL (The Netherlands) to support the Declaration of Equivalence between NIST and NMi VSL in the gas analysis field. Furthermore, results will be presented of a major gas analysis interlaboratory scheme that NMi VSL is organizing for the worldwide production locations of oil company Shell. We started this exercise in 2003 and the very good news is, that the scheme recently became completely open. As such any laboratory is welcome to join the scheme. Based upon the success of the now called Correlation Scheme, NMi VSL started a marketing theme group to explore possibilities for a wider participation in interlaboratory comparisons. Although ISO/IEC 17025 requires participation, laboratories are not very willing to participate freely! Measurement precision is a hidden quality at all laboratories. It usually attracts attention if measurements fail to match those of other laboratories, indicating that there might be some kind of problem. Prior to that, no news is good news. So, how can we raise awareness? Ideas to achieve this are presented.
Dairy in Your Child's Diet

includes foods from all the food groups. The dairy group is especially important for children and youth because of the high amounts of protein, calcium, and vitamin D that are used to build strong bones and reduce the risk of chronic diseases later in life (Thorning et al., 2016). This fact sheet will present the health benefits of dairy and bust some common myths to assist you in making informed decisions when purchasing dairy products for your children. This fact sheet also includes information on dairy alternatives for children who, for one reason or another, do not consume dairy products.
The Incident of Heart Diseases in Hypertension in Bangladesh

Introduction: For cardiovascular disease (CVD), hypertensionis the strongest risk factor. Objective: In this study our main aim is to discover the incident of heart diseases in hypertension of hypertension in Bangladesh. Method: This cross-sectional study was conducted at different private hospital in Khulna from January 2015 to January 2016 where 530 rural and urban individuals (age ≥21 years) were evaluated and all data was recorded methodically in a preformed data sheet and was analyzed by relevant statistical procedures. Results: in the study 99 male and 64 female belongs to hypertension group. Also, age and heart diseases strongly correlated with hypertension. Conclusion: we can conclude that in Bangladesh patients with hypertension is prone to have heart diseases. More studies are suggestive to estimate the incidence of hypertension in heart diseases.
Variação intrapopulacional para vigor inicial e hábito de crescimento em três populações de azevém.

1 Graduanda em Agronomia,UFPel, bolsista Embrapa Gado de Leite– angelicahalfen.agronomia@gmail.com 2 Tecnico em Agricultura, Embrapa Clima Temperado– zandrosp@hotmail.com 3 Graduando em Zootecnia, UFPel, bolsista Embrapa Clima Temperado– eliezercp@hotmail.com 4 Graduanda em Agronomia, UFPel, bolsista Embrapa Clima Temperado– leka.helensantos@gmail.com 5 Embrapa Gado de Leite/ Embrapa Clima Temperado – andrea.mittelmann@embrapa.br
Modelado borroso de referencias geográficas textuales sobre datos de expertos

∗ Centro Singular de Investigación en Tecnoloxı́as da Información (CiTIUS), Universidade de Santiago de Compostela alejandro.ramos@usc.es josemaria.alonso. moral@usc.es † Department of Computing Science, University of Aberdeen alejandro.soto@abdn.ac. uk e.reiter@abdn.ac. uk k.vdeemter@abdn.ac. uk ‡ Department of Information and Computing Sciences, Utrecht University k.vandeemter@uu.nl § Institute of Linguistics and Language Technology, University of Malta albert.gatt@um.edu. mt
Décomposition arborescente des graphes planaires et routage compact

Savoir comment transmettre une information est fondamental dans un reseau. Il est essentiel que chaque entite du reseau soit capable de decider localement, avec sa vue du reseau, du chemin par lequel l'information doit passer. Ainsi, il est souvent utile d'etudier la topologie du reseau, modelisee par un graphe, pour repondre a ces exigences. Nous nous interessons dans un premier temps, a la decomposition arborescente des graphes planaires. En effet, comme dans beaucoup de problemes de graphes, l'etude de la topologie des graphes nous conduit a proceder a une decomposition du graphe afin d'exploiter les proprietes structurelles qui en decoulent. En suite, nous nous sommes aussi interesses a la structure des graphes qui excluent un mineur H, en particulier le graphe K_{2,r}. Ces travaux nous ont permis d'ameliorer les bornes actuelles connues sur la largeur arborescente de ces graphes. Dans la derniere partie, nous abordons le probleme du routage compact. Nous nous sommes interesses aux schemas de routage de plus courts chemins utilisant des adresses, des tables de routage de tailles optimales de O(log n) bits, ou n est le nombre de sommets du graphe. Nous proposons un tel schema de routage pour une famille de graphes values contenant les arbres et les graphes planaire-exterieurs.
Caracterización del ictus en grupo de adultos mayores atendidos en el hospital “Dr. León Cuervo Rubio”, 2015-2017

Introduccion: el envejecimiento poblacional, trae aparejado un alza de las enfermedades cronicas no transmisibles, incluyendose en este grupo el ictus. Objetivo: caracterizar el ictus en grupo de adultos mayores. Material y metodos: estudio observacional descriptivo longitudinal, realizado en el hospital Dr. Leon Cuervo Rubio entre junio de 2015 a enero de 2017. Fue seleccionada aleatoriamente una muestra de 138 adultos mayores con ictus diagnosticado, respetandose los criterios de inclusion y exclusion. El interrogatorio, revision de la historia clinica, y la aplicacion de instrumentos permitieron obtener la informacion, que dio salida a las variables estudiadas. Se respetaron los principios eticos. Resultados: predominaron las feminas (60,14 %), el grupo etareo 60-69 anos de edad (47,10 %), y el ictus isquemico (87,68 %), siendo el infarto aterotrombotico el mas representativo (42,98 %). El consumo de una dieta aterogenica (87,68 %) fue el principal factor de riesgo, siendo la paralisis de miembros (52,17 %) la principal secuela. Predomino la afectacion neurologica grave y el deterioro cognitivo (35,51 y 52,17 % respectivamente), mostrando la escala Rankin modificada predominio de los adultos mayores que se encontraban moderadamente (28,26 %) mientras el indice de Barthel mostro predominio de los dependientes severos (32,61 %). Conclusiones: la caracterizacion de los pacientes con ictus permitio conocer las particularidades de dicho grupo, lo cual permite trazar estrategias de trabajo con dicha poblacion, lo cual permita una mejoria de su calidad de vida; asi como identificar que factores deben ser estudiados en grupos propensos a desarrollar dicha enfermedad, previniendo su aparicion.
Conflict resolution following aggression in gregarious animals: a predictive framework

Knowledge of how animals manage their conflicts is critical for understanding the dynamics of social systems. During the last two decades research on gregarious animals, especially primates, has focused on the mechanisms of conflict management, mainly on friendly postconflict reunions (also called ‘reconciliation’) in which former opponents exchange affiliative behaviour soon after an aggressive conflict. Our aim in this paper is to present a framework in which the costs and benefits of friendly postconflict reunions, both for each individual opponent and for their mutual relationship, are used to predict the patterning of postconflict resolution mechanisms in other gregarious animals. The framework predicts the occurrence of postconflict reunions in species that live in stable social units, have individualized relationships, and experience postconflict hostility, but especially in those in which intragroup aggression disrupts valuable relationships. The critical issue is whether aggressive conflicts occur between cooperative partners and whether the level of aggression is sufficient to jeopardize the benefits associated with such valuable relationships. We conclude by proposing four research priorities to evaluate the role of friendly reunions in negotiating relationships and the way they are themselves influenced by asymmetries in partner value and biological market effects.
Consumidores Millennials: las gratificaciones a través del uso de Snapchat y su impacto a motivaciones impulsivas de compra

espanolUtilizando los resultados de 454 participantes de la generacion Millennials, a traves de la teoria de Usos y Gratificaciones los investigadores analizan como las estrategias de contenido a traves de Snapchat impactan el uso y lo que se comparte en los contenidos. Ademas, se analizan las motivaciones a compras impulsivas. Este estudio exploratorio de tipo transversal utiliza la metodologia cuantitativa a traves de una encuesta aplicada. Los investigadores emplean el uso de ecuaciones estructurales de minimos cuadrados parciales (SMART PLS). Los resultados finales contribuyen a la teoria a traves de la identificacion de factores de gratificacion como interaccion, manejo de relaciones, ahorro en compras, informacion, interactividad, facil acceso al contenido, entretenimiento, creatividad, diversion y dinamismo. EnglishThis research examines data on 454 participants from the millennial generation. Through the theory of uses and gratifications, the researchers analyze how content strategies employed by the Snapchat impact the use and sharing of content. In addition, motivations for impulsive purchases are analyzed. This exploratory study uses quantitative methodology through an applied survey. The researchers make use of partial least squares structural equations (SMART-PLS). The results contribute to the theory through the identification of gratification factors such as interaction, relationship management, purchase savings, information, interactivity, easy access to content, distraction, creativity, fun and dynamism.
Assessment of Effects of Prebiotics Supplementation on Feed Intake, Egg and Serum Cholesterol Levels in White Leghorn Layers

The present study was undertaken to evaluate the effect of supplementation of graded levels of prebiotics on feed intake, egg yolk cholesterol, serum cholesterol levels and internal egg quality parameters in White Leghorn layers. An experiment trial was run for a period of 16 weeks with eighty White Leghorn layers in the age group of 22–23 weeks of age were allotted randomly to four dietary treatments having 4 replications with 5 birds each. The control diet (T1) was formulated as per the BIS (2007) meeting the requirements for laying phase of the hens in the age group of 22–38 weeks. In addition, the birds in treatments T2, T3 and T4 were supplemented with prebiotics (containing mannonoligosacchrides of the Saccharomyces cell wall-47 g, formic acid (85%)-32 g, HSCAS upto 1 kg) @ 0.5, 1.0 and 2.0 g/kg of feed, respectively. Laying hens receiving prebiotics exhibited improvement in feed conversion ratio of 3.83 and 7.34% in treatment groups T3 and T4, respectively compared to control. The prebiotics supplementation showed positive effect on internal egg quality parameters viz. albumen index, yolk index and Haugh unit in layers supplemented with graded levels of the prebiotics as compared to the control group. Maximum increase of 1.92% in albumen index and 2.06% in Haugh unit was observed in treatment T4 as compared to T1. However, no significant effect was observed for yolk index. Also, a significant (P<0.05) reduction was observed in the serum as well as egg yolk cholesterol and low density lipoproteins (LDL) concentrations while egg yolk high density lipoproteins (HDL) concentrations were not affected. Thus, the present study showed that administration of prebiotics had positive effect on serum and egg cholesterol levels without any changes in HDL levels.
Innovation and Micro and Small Enterprises Growth Performance: Evidence from Kenya

: The role that innovation can play towards the growth and survivalof an enterprise continues to gain credence as better indicators of enterprise innovativeness come to the fore. In spite of this growing body of knowledge, micro and small enterprises in Kenyacontinue to experience high mortality rate. This paper used World BankEnterprise Survey data for Kenya to probe whether innovative micro and small enterprisesare indeed associated with better growth performance. The study used a qualitative analysis using a descriptive analysis and t-test for mean differences to compare innovative and non-innovative micro and small enterprises. The results show that there was no statistically significant relationship between a micro and small enterprise’s growth performance and its innovativeness. Innovative micro and small enterprises were, however, found to have invested relatively higher resources towards innovation inputs and hiring of advanced human skills. They also participated in export trade. The results seems to suggest that innovative micro and small enterprises’ investment were either too marginal to make a difference or the investments dissipated along the innovation chain.