Miracle-dz/UniFAR-FTUs huggingface dataset:
Anterior Cervical Pseudarthrosis: Natural History and Treatment

Study Design. A retrospective study of long‐term clinical outcomes in 48 patients with pseudarthroses after anterior cervical discectomy and fusion. Objectives. To determine the natural history, risk factors, and treatment outcomes in a large population with documented pseudarthrosis after anterior cervical discectomy and fusion. Summary of Background Data. Recent reports suggest that pseudarthrosis after anterior cervical discectomy and fusion adversely affects clinical outcome. Little data regarding cervical pseudarthroses have been published, and conclusions have been drawn from reports with small patient populations and short‐term follow‐up periods. Methods. Forty‐eight patients with radiographically documented pseudarthrosis after anterior cervical discectomy and fusion were studied. Patients were examined and radiographs made at regular intervals (mean follow‐up, 66 months). Clinical results were based on patients' assessment of pain, prescription drug use, activity level and Odom's criteria. Clinical outcomes in patients who underwent surgical repair of the pseudarthrosis are reported. Results. Of the 48 patients, 32 (67%) with pseudarthroses were symptomatic at latest follow‐up or at the time of further surgery. Of the 32 patients, 9 had a symptom‐free period of at least 2 years after the anterior cervical discectomy and fusion before redeveloping cervical symptoms after a traumatic episode. Of 48 patients with pseudarthroses, 16 (33%) remained asymptomatic at a mean of 5.1 years after anterior cervical discectomy and fusion. A younger age at the time of anterior cervical discectomy and fusion increased the likelihood of the pseudarthrosis becoming symptomatic. After multiple level anterior cervical discectomy and fusion, the caudal‐most operated level accounted for 82% of the pseudarthroses. Sixteen patients had an anterior repair of the pseudarthrosis, and fusion was achieved in 14. Six patients underwent posterior pseudarthrosis repair, and all healed. In patients in whom fusion was achieved with a second cervical operation, the results were excellent in 19 and good in 1. Conclusion. A pseudarthrosis after anterior cervical discectomy and fusion is frequently associated with a poor clinical outcome. Surgical repair of the pseudarthrosis with an anterior or posterior approach seems to have a high likelihood of a successful clinical outcome.
JOINT ESC GUIDELINES 2016 European Guidelines on cardiovascular disease prevention in clinical practice – Web Addenda

Authors/Task Force Members: Massimo F. Piepoli* (Chairperson) (Italy), Arno W. Hoes* (Co-Chairperson) (The Netherlands), Stefan Agewall (Norway)1, Christian Albus (Germany)9, Carlos Brotons (Spain)10, Alberico L. Catapano (Italy)3, Marie-Therese Cooney (Ireland)1, Ugo Corrà (Italy)1, Bernard Cosyns (Belgium)1, Christi Deaton (UK)1, Ian Graham (Ireland)1, Michael Stephen Hall (UK)7, F. D. Richard Hobbs (UK)10, Maja-Lisa Løchen (Norway)1, Herbert Löllgen (Germany)8, Pedro Marques-Vidal (Switzerland)1, Joep Perk (Sweden)1, Eva Prescott (Denmark)1, Josep Redon (Spain)5, Dimitrios J. Richter (Greece)1, Naveed Sattar (UK)2, Yvo Smulders (The Netherlands)1, Monica Tiberi (Italy)1, H. Bart van der Worp (The Netherlands)6, Ineke van Dis (The Netherlands)4, W. M. Monique Verschuren (The Netherlands)1
Effects of somatostatin on plasma glucose and glucagon levels in human diabetes mellitus. Pathophysiologic and therapeutic implications.

Abstract To evaluate the role of pancreatic alpha-cell dysfunction in human diabetes mellitus, somatostatin, an inhibitor of glucagon secretion, was infused (1 mg over two hours) in 10 insulin-dependent diabetic subjects. Fasting plasma glucagon fell from 150 ± 15 (mean ± S.E.M.) to 77 ± 10 pg per milliliter (p<0.001), and plasma glucose from 260 ± 20 to 191 ± 21 mg per 100 ml (p<0.001). Similar responses occurred in a hypophysectomized diabetic patient, indicating that these effects of somatostatin were independent of suppression of growth hormone secretion. Somatostatin (4 mg subcutaneously) was active transiently. In additional studies, somatostatin infusion combined with insulin completely abolished post-meal hyperglycemia in four diabetic patients and was more effective than insulin alone. These results indicate that excessive glucagon secretion accounts for about 25 per cent of the fasting plasmaglucose levels in such patients. Furthermore, somatostatin may be a useful adjunct to insulin in treating.
Supporting Exploratory Search with a Visual User-Driven Approach

Whenever users engage in gathering and organizing new information, searching and browsing activities emerge at the core of the exploration process. As the process unfolds and new knowledge is acquired, interest drifts occur inevitably and need to be accounted for. Despite the advances in retrieval and recommender algorithms, real-world interfaces have remained largely unchanged: results are delivered in a relevance-ranked list. However, it quickly becomes cumbersome to reorganize resources along new interests, as any new search brings new results. We introduce an interactive user-driven tool that aims at supporting users in understanding, refining, and reorganizing documents on the fly as information needs evolve. Decisions regarding visual and interactive design aspects are tightly grounded on a conceptual model for exploratory search. In other words, the different views in the user interface address stages of awareness, exploration, and explanation unfolding along the discovery process, supported by a set of text-mining methods. A formal evaluation showed that gathering items relevant to a particular topic of interest with our tool incurs in a lower cognitive load compared to a traditional ranked list. A second study reports on usage patterns and usability of the various interaction techniques within a free, unsupervised setting.
ANALISIS REVALUASI AKTIVA TETAP DI PT INDONESIA POWER

ABSTRAKRevaluasi aktiva tetap untuk tujuan perpajakan adalah melakukan penilaian kembali aktiva tetap dengan memanfaatkan fasilitas revaluasi sebagaimana diatur dalam Peraturan Menteri Keuangan Nomor 191/PMK.010/2015 jo. PMK Nomor 233/PMK.03/2015 khusus pada tahun 2015 dan 2016, tarif pajak penghasilan atas selisih lebih penilaian kembali berubah yaitu 3% untuk penilaian kembali aktiva pada tahun 2015, 4% untuk penilaian kembali aktiva pada 1 Januari sampai dengan 30 Juni 2016 dan 6% untuk penilaian kembali aktiva pada 1 Juli sampai dengan 31 Desember 2016. Tujuan penelitian ini adalah untuk menganalisis revaluasi aktiva tetap untuk tujuan perpajakan yang dilakukan oleh salah satu anak usaha BUMN dan manfaat ekonomi yang diperolehnya. Metode yang digunakan dalam penelitian ini adalah kualitatif deskriptif. Objek penelitian ini adalah PT Indonesia Power yang merupakan anak usaha BUMN. Data yang digunakan adalah laporan keungan tahun 2015 dan laporan revaluasi asset. Hasil penelitian ini menunjukkan bahwa revaluasi aktiva tetap untuk tujuan perpajakan dapat meningkatkan laba bersih, aset, dan ekuitas, revaluasi aktiva juga dapat memberikan manfaat berupa berkurangnya pajak penghasilan untuk tahun setelah revaluasi serta manfaat ekonomi lainnya, yaitu performa keuangan yang meningkat.
Contributions aux statistiques cycliques d'ordre supérieur : applications au diagnostic des défauts d'engrenage

L'objectif de cette these est l'analyse vibratoire et celle d'emission acoustique (EA) des engrenages dans les machines tournantes pour le diagnostic de leur etat de fonctionnement mecanique. Dans une premiere partie, nous nous interessons au potentiel de l'EA en fournissant une comparaison avec les vibrations. Nous montrons la complementarite entre les deux techniques pour avoir un diagnostic fiable. Des descripteurs simples sont testes tels que le kurtosis. Dans une deuxieme partie, une modelisation generique des signaux d'engrenages est proposee. Cette modelisation vise a demontrer la cyclostationnarite aux ordres superieurs des signaux d'engrenage. Nous explicitons ensuite la theorie du bispectre cyclique, outil statistique a l'ordre trois. A la fin, nous proposons des indicateurs de cyclostationnarite concis et utiles au diagnostic. Des applications aux signaux vibratoires de machines tournantes sont detaillees.
A Deep Convolutional Neural Network for Anomalous Online Forum Incident Classification

Web forums are a frequent way of sharing useful information among people. They are becoming the main source of up-to-date information and market-places pertaining to different domains, including criminal content and zero-day security exploits. Analyzing the web forums of the existing discussion threads is an alternative method to understand the exploits and fraud modalities a law breaker will most likely make use and how to defend against them. However, in many cases, it is hard to capture all the relevant context of the forums which is needed for clas-siﬁcation. In this paper, we introduce a data-driven technique to mine the web forums and provide policy recommendations to the defender. A neural network (NN) is used to learn the set of features for forum classiﬁcation. Furthermore, we present the evaluation and results from employing our method, with various system conﬁg-urations, on real-world datasets collected form the web.
Time-limited sensitivity groups for medical students.

Dehumanizing trends in medical education have been reported and discussed extensively. In response to this problem, the opportunity to join a voluntary, time-limited, unstructured sensitivity group was offered to medical students during their clinical rotation in psychiatry. These groups proved to be safe forums for experiential education in which students could increase their capacity to respond sensitively to themselves and others. This paper describes three phases of the group process, the role of the group leader, and the reactions of the participating students.
Una herramienta automática de feedback para ensamblador

Un estudiante de primer curso de Ingenieria en Informatica debe adquirir la capacidad de analizar y depurar codigos, tanto a alto nivel como en ensamblador. Este proceso requiere una participacion activa por parte de los estudiantes, sobre todo en el laboratorio. Sin embargo, un entorno de laboratorio desconocido y la falta de conocimientos previos llevan a los alumnos a basar su aprendizaje en la realimentacion (feedback) ofrecida por el profesor. Esta dependencia hace que los alumnos no utilicen el software de laboratorio para solucionar los problemas de teoria y trabajar de forma autonoma. Ademas, la mayoria de las preguntas de los estudiantes son siempre las mismas, y pueden ser resueltas de manera facil y rapida. Sin embargo, el profesor no esta disponible en todo momento, por lo que una pregunta que podia resolverse en segundos mantiene al estudiante atascado durante minutos, hasta que dispone del profesor. Para solucionar esta situacion se ha desarrollado el entorno SISA-EMU, que permite comprobar rapidamente si una solucion es correcta. Ademas incorpora un sistema de realimentacion automatico que orienta a los alumnos sobre los errores que han cometido. Con esta herramienta se fomenta que los alumnos trabajen de forma semiautonoma y obtengan un mayor provecho de los problemas realizados.
Kbg : induction de bases de connaissances en logique des predicats

Dans un grand nombre de problemes concernant le monde reel, les systemes d'apprentissage utilisant un langage de representation des connaissances base sur la logique des propositions, ne peuvent etre utilises. Inversement, si les systemes travaillant en logique des predicats offrent des possibilites de representation plus etendues, notamment en ce qui concerne l'expression de relations entre les objets, ils sont souvent incapables de traiter efficacement les informations de type numerique. Dans cette these, nous presentons une methode d'apprentissage empirique permettant de construire de facon automatique des systemes hierarchiques de regles exprimees en logique d'ordre un. En outre, le systeme propose est capable de gerer efficacement a la fois des connaissances de type quantitatives et procedurales. La base de connaissances apprise est elaboree au moyen d'une utilisation iterative d'operateurs de generalisation et de classification conceptuelle
The Prevalence of Common Milk Borne Pathogens of Camelus Mastitis Origin and their Antibiotic Resistance in North Eastern Province, Kenya

In most pastoral communities, camel milk is consumed raw without any heat treatment and this can pose a health hazard to consumers. Camels are milked in poor sanitary conditions, with all the predisposing factors to mastitis that include dust, flies and scarce water resources among others. Whenever mastitis is encountered in the field, antibiotic treatment is the basis of most treatment regimes. In most of the cases the treatment is given without the benefit of bacteriological examination as laboratories are non-existent in many such areas. Use of inadequate or inappropriate dosage of antibiotics may lead to generation of bacteria resistant to the commonly used antibiotics. It is therefore important to determine prevalence of the most common milk pathogens in camel milk such as Staphylococcus and Streptococcus spp, from North Eastern province marketed in urban areas, as well as the extent of their antibiotic resistance. Isolation and identification of the bacteria was done with a total of 207 milk samples that were collected in Garissa and Wajir. The prevalence of Staphylococcus aureus and Streptococcus agalactiae in the whole region were found to be 22.76% and 22.74%, respectively. However, the prevalence in the two districts differed with Garissa having higher percentage prevalence both for Staphylococcus aureus (34.95%) and Streptococcus agalactiae (37.79%) compared to Wajir (10.58% and 7.69%, respectively).
Folic acid inhibition of EGFR-mediated proliferation in human colon cancer cell lines

RICHARD JASZEWSKI,1,2 AHMED KHAN,2 FAZLUL H. SARKAR,3,5 OMER KUCUK,2 MARTIN TOBI,1,2 ABBAS ZAGNOON,1,2 RAVI DHAR,2 JOSEPH KINZIE,2 AND ADHIP P. N. MAJUMDAR1,2,4,5 1John D. Dingell Veterans Affairs Medical Center and Departments of 2Internal Medicine, 3Pathology, and 5Biochemistry and Molecular Biology, and 4Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan 48201
A mirror for patients with hemianopsia.

Hemianopsia is relatively frequent among patients with intracranial lesions. Most of these defects are of the nature of a homonomous hemianopsia. Patients with this disability often complain of the repeated dangers and embarrassments which occur as the direct result of their restricted field of vision. They fail to see swiftly moving automobiles, they are afraid to gaze into shop windows because of the probability of colliding with other pedestrians and they fail to see the food passed to them at the dinner table. The complaint is usually worded thus: "If I only knew that something were approaching me on my blind side, I could turn my head and look over there—but I don't know when to look. " In an effort to find some gadget which would aid these patients in "knowing when to look," a simple device, consisting only of a small, oval mirror measuring about 1 by 2 cm. ,
The incretin effect and its potentiation by glucagon-like peptide 1-based therapies: a revolution in diabetes management

The incretin effect is a phenomenon in which enteral glucose administration provokes greater insulin secretion than intravenous administration. The main incretins, glucose-dependent insulinotropic peptide and glucagon-like peptide (GLP)-1 are defective in Type 2 diabetes; whereas glucose-dependent insulinotropic peptide displays diminished effectiveness, GLP-1 secretion is decreased; thus, GLP-1 was a stronger candidate for a new class of anti-diabetic agents designed to potentiate the incretin effect. In the past decade, GLP-1 mimetics, peptidase inhibitors and GLP-1 have been developed. Early randomised trials show that these agents contribute to glucose homeostasis and enhance β-cell function, without causing hypoglycaemia or weight gain. This review includes an historical perspective, physiology of incretins, and discussions of the pathophysiology in Type 2 diabetes, pharmacology of the main agents and randomised clinical trials published to date.
Significance of Vascular Endothelial Growth Factor (VEGF)-C and VEGF-D in the Progression of Cutaneous Melanoma

Introduction. Induction of tumor lymphangiogenesis by vascular endothelial growth factor (VEGF)-C and VEGF-D promotes metastasis in many human cancers. Aim. The aim of this study was to examine the role of VEGF-C and VEGF-D in lymphangiogenesis and lymph node metastasis in patients with cutaneous melanoma. Materials and Methods. Fifty-four melanoma specimens (18 with lymph node metastasis, 36 nonmetastatic) were investigated by immunostaining for VEGF-C, VEGF-D, and for lymphatic endothelial marker D2-40. VEGF-C and VEGF-D expression was assessed as a percentage and intensity of stained tumor cells, tumor-associated macrophages and fibroblasts. The quantification of lymphangiogenesis was conducted by computer-assisted morphometric analysis. Results. The expressions of both VEGF-C and VEGF-D in tumor cells were significantly higher in lymph node metastatic melanomas compared with nonmetastatic melanomas (P = .015 VEGF-C; P = .005 VEGF-D). There was no statistically significant difference between metastatic and nonmetastatic melanomas regarding the expression of VEGF-C and VEGF-D in macrophages and fibroblasts. Metastatic melanomas showed a significantly higher intratumoral and peritumoral lymphatic vessel density (LVD) compared with nonmetastatic melanomas (P = .000 intratumoral, P = .000 peritumoral). Melanomas with VEGF-C positive tumor cells showed a significantly higher intratumoral and peritumoral LVD compared with VEGF-C negative tumor cells group of melanomas (P = .006 intratumoral, P = .010 peritumoral). VEGF-C expression in macrophages, fibroblasts, as well as VEGF-D expression in tumor cells, macrophages, and fibroblasts, showed no correlation with the intratumoral and peritumoral LVD. Conclusions. Our findings show the significance of VEGF-C in tumor cells in the induction of intratumoral and peritumoral lymphangiogenesis. This study suggests that both VEGF-C and VEGF-D in tumor cells promote lymph node metastasis, and that the immunohistochemical analysis of expression can be a useful tool for predicting clinical behavior of cutaneous melanoma.
A Physics-Based Analytic Solution to the MOSFET Surface Potential From Accumulation to Strong-Inversion Region

A physics-based analytic solution to the surface potential from the accumulation to the strong-inversion region has been derived from the complete MOSFET surface potential equation in this paper without any need for smooth functions or simplification by dropping some second-order related terms. Its high accuracy in predicting the surface potential and the transcapacitance under various bias conditions has also been verified by a comparison with the numerical results. The explicit surface-potential solution not only leads to a more clear understanding of MOSFET device physics but also provides a better platform to develop the advanced surface potential-based model for the circuit simulation
Towards a deeper understanding of in-store shopping behavior. Virtual Reality: breakthrough in shopper insights

Today’s shopper is different from yesterday’s and probably wouldn’t relate to tomorrow’s. The way shoppers shop has changed with the proliferation of technology. More connected and knowledgeable, they gained the power over brands and retailers. This dynamic is sending shockwaves through companies who turn to Market Research to better understand their shoppers in order to upsell them and thrive. The purpose of this paper is to contextualize the need of new Shopper Insights whilst the fastchanging demands and the ever-shifting shopper behavior with a mere given attention to in-store where a great deal of decision making is made, examine the state of art of current shopper research methods employed and delineate where they fall short to eventually instance how technological advances in Virtual Reality enable researchers garner faster, realistic and reliable feedback into shopper behavior.
CCK and Barker Coding Implementation in IEEE 802.11b Standard

This paper deals with a Matlab-simulink simulation of IEEE 802.11b physical Layer specification. There was made a Matlab Simulink program that simulates 4 data rates (1, 2, 5.5, 11 Mbps) specified in the 802.1 lb standard. Program includes Barker coding implementation for lower data rates (1,2 Mbps) and CCK (complementary code keying) for higher data rates providing 5.5 and 11 Mbps. All data rates are using DSSS (direct sequence spread spectrum). Basic description of the program and results in graphical and numerical form are introduced as a BER to Eb/NO dependence.
A novel type of microglomerular synaptic complex in the polarization vision pathway of the locust brain

The lateral accessory lobes (LALs) are prominent integration centers in the insect brain. In the desert locust Schistocerca gregaria, they are connected with the anterior optic tubercles (AOTus), with the central complex, and with the ventral nerve cord. Two subcompartments of the LALs, the lateral triangle and the median olive, are easily recognized by their prominent granular texture. Both areas are part of the polarization vision pathway in the locust brain; they receive input from projection neurons of the AOTu and are the site of presumed dendritic arborizations of tangential neurons of the lower division of the central body. Both types of neuron are sensitive to polarized light and most likely play a role in sky compass navigation of the locust. We show here that neurons from the AOTu and tangential neurons of the central body form large microglomerular contacts in the median olive and lateral triangle. Presynaptic elements from the AOTu end in small numbers of large cup‐shaped terminals. These cups enclose many small γ‐aminobutyric acid (GABA)‐immunoreactive (‐ir) profiles from tangential neurons of the lower division of the central body. Each cup‐shaped profile makes numerous (>150) dyadic output synapses with the small postsynaptic GABA‐ir profiles. No synaptic connections were found between the small core profiles. The microglomerular organization of the median olive and lateral triangle is unlike that of any other synaptic microglomeruli reported for the insect brain. It might provide precise spike timing information possibly used to extract spatial information by comparison of binocular inputs in the central complex. J. Comp. Neurol. 506:288–300, 2008. © 2007 Wiley‐Liss, Inc.
Zoning Transformation at Sport Center and Its Influence Toward Housing-Case Study: Arcamanik Sport Center and Arcamanik Housing in Indonesia

Housing and settlements in Indonesia continue to grow to meet the needs of people in their homes. This increase is growing with other facilities, to become a sports facility, as happened in Arcamanik settlement, in city of Bandung, Indonesia. In development of its housing function, there are other function changes that occur in the residential building. That is a change of dwelling house that develops as a place of business. These housing and settlements prioritize quality of community life by building public and social facilities, especially in the health sector such as the Sport Center area. Activity of this sports center is growing up to the national game in Indonesia. By doing research on the activities of the sports center that occurred, and development of changes in function of housing, the resulting transformation zoning that occurs. Expected to improve the health and success of urban areas.