Molecular characterization of HIV-1 Subtype C strains from KwaZulu-Natal, South Africa, with a special emphasis on viral fitness and drug resistance.

s presented or accepted 1. Gordon M, Graham N, Ruth Bland, Nigel Rollins, Claassen M, Coovadia HM, Bennish M, Cassol S. Resistance patterns in mother-infant pairs following single dose nevirapine (NVP) for the prevention of mother-to-child transmission (MTCT) of HIV1. XIV International AIDS Conference, Bangkok, Thailand, July 12-16, 2004. 2. Gordon M, Graham N, Van Laethem K, Giddy J, Hampton J, Bishop K and Cassol S Surveillance of Antiretroviral Drug Resistance in a single HIV Clinic in KwaZuluNatal (KZN) South Africa. XIV International AIDS Conference, Bangkok, Thailand, July 12-16, 2004. 3. Gordon M, Graham N, Bland R, Rollins N, De Oliveira T, Monosi B, Van Laethem K, Vandamme A, Cassol S. Surveillance of Resistance in KZN South Africa, including mother-infant pairs 6 weeks after single dose NVP. XIII International Drug Resistance Workshop, Tenerife, Spain, June 8-12, 2004. 4. De Oliveira T, Salemi M, Gordon M, Vandamme A, Cassol S. Evolutionary evidence that HIV-1 Tat and Rev are targets of strong positive selection: new insights for designing an AIDS vaccine? Oral Presentation at 10th International Workshop on HIV Dynamics and Evolution. UCLA Conference Center, Lake Arrowhead, California, April 13th-16th, 2003. 5. De Oliveira T, Miller R, Gordon M, Cassol S. An integrated Genetic Data Environment (GDE)-based LINUX interface for analysis of HIV-1 and other microbial sequences. Poster presentation at 10th International Workshop on HIV Dynamics and Evolution. UCLA Conference Center, Lake Arrowhead, California, April 13-16, 2003. 6. Chelule PK, Mosam A, Gordon M, Palanee T, Page T, Coovadia HM, Cassol S. Preparing for HIV-1 therapy in South Africa: Will host polymorphisms in MDR1 and CYP3A4 influence therapeutic outcome? 2nd IAS Conference on HIV Pathogenesis and Treatment. Paris, July 13th-16th, 2003. 7. Gonzalez LMF, Brindeiro R"M, Tarin M, Calazans A, Soares MA, Cassol S, Tanuri A. In vitro susceptibility to protease inhibitor from subtype C of human immunodeficiency virus type 1 isolates. 2nd IAS Conference on HIV Pathogenesis and Treatment. Paris, France, July 13th-16th, 2003. 8. Gordon M, De Oliveira T, Darder M, Bishop K, Cassol S. Resistance patterns of HIV1 subtype C in South African patients failing highly active antiretroviral therapy (HAART). South Africa AIDS Conference, International Convention Centre, Durban, South Africa, August 3-6, 2003. 9. De Oliveira T, Salemi M, Tarin M, VanDamme AM, Cassol S. Detecting positive selection sites in the HIV subtype C complete genome. Annals of the 9th HIV Dynamics and Molecular Evolution Conference, Lake Arrowhead, CA, United States, 2002. 10. Tarin M, Oliveiro T, Bishop K, Smith A, Madurai L, Cassol S. Characterization of the reverse transcriptase (PR) and protease (PR) genes of treatment-naive patients from KwaZulu-Natal (KZN) South Africa. XIV International AIDS Conference, Barcelona, Spain, July 7-12, 2002. 11. Tarin M, De Oliveira T, Bishop K, Cassol S. Africa Centre for Health and Population Studies, Nelson R. Mandela School of Medicine, University of Natal, Durban, South Africa. Comparison of Retrospective and Recent Reverse Transcriptase (RT) and Protease (PR) Sequences from Treatment-Naive Patients in KwaZulu-Natal (KZN) and Cape Town, South Africa. XI International Drug Resistance Workshop, Seville, Spain, July 2-5, 2002. 12. De Oliveira T, Bishop K, Tarin M, Engelbert S, Cassol S. Detecting adaptive molecular evolution in HIV-1 subtype C complete genomes. 9th International Workshop on HIV Dynamics and Evolution, UCLA, Los Angeles, March 17-20.