Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Chronic Electronic Vapor Exposure on Body Weight, Appetite, and Metabolism

Effects of Chronic Electronic Vapor Exposure on Body Weight, Appetite, and Metabolism Matthew J. Breit Cigarette smokers weigh less than non-smokers and gain weight upon smoking cessation. Electronic cigarettes (E-cigs) have been used as a smoking cessation tool among many, however, their effects on metabolism, appetite, and energy balance are virtually unknown. This study compares the effects of chronic E-cig vapor exposure on body mass, food intake, metabolism, and body composition in mice. We hypothesized that E-cig exposure would elicit similar changes on body mass, body composition, food intake, and metabolic and appetite-regulating markers as conventional cigarettes (i.e. 3R4F reference cigarette). Female C57BL/6 mice were exposed to filtered room air (n=15), mainstream smoke from 3R4F reference cigarettes (n=15), or E-cig vapor (n=15) for a total of 8-months (4 h/d, 5d/wk). Body mass, food intake, metabolic and appetite-regulating markers, heat production, and body composition were measured. Weight gain, fat-free mass (FFM), and fat mass were significantly elevated in E-cig and control mice compared to 3R4F mice. Food consumption and heat production (kcal expended/hr) was significantly increased in E-cig mice compared to control and 3R4F mice. Appetiteregulating markers (NPY, POMC, leptin, and GLP-1) were similar between all groups. Mitochondrial uncouplers (UCP-1 and UCP-3) remained unchanged between E-cig and control groups, however, UCP1 was significantly elevated in E-cig mice compared to 3R4F mice and UCP-3 was significantly elevated in control vs. 3R4F mice. Oxygen consumption (VO2) and carbon dioxide production (VCO2) were also significantly elevated in E-cig and 3R4F mice compared to control mice, while respiratory exchange ratios (RER) were unchanged. Unlike conventional cigarettes, we found that E-cig exposure did not elicit reductions in total body or adipose mass. This suggests the effects of E-cig may not be the same as that occurring with traditional tobacco cigarettes, or that the exposure to nicotine and/or other chemicals in the E-cig liquid elicits a different response on appetite or feeding behavior. While E-cig mice increased food intake, their basal metabolism was also elevated, suggesting energy dissipation resulting in a similar net energy balance compared to control mice. Further studies are needed to evaluate the effect that flavorings and/or the compounds produced in E-cig vapor exert on metabolism, energy balance, and the neural regulation of appetite.
The effect of endometrial thickness and pattern on pregnancy outcome in IVF / ICSI cycles

The purpose of this study is to reveal the impact of endometrial thickness and endometrial pattern on pregnancy rates, in cases, at least, one grade 1 quality embryo transfer done from IVF and ICSI applied patients. We included the 440 cases into our studies in which at least one grade 1 quality embryo transfer done from IVF or ICSI applied patients in our in vitro fertilization clinic at our hospital between the years 2007 and 2010. The studies’s parameters consisted of the cases’ age, body mass index (BMI), indication, basal FSH levels, endometrial thickness measured on the hCG day and endometrial pattern, applied drug protocol, E2 values on the day of hCG. Pregnancy detection was confirmed 12 days after the transfer by βhCG measuring and ultrasonography of the embryonary sac. Our patients’ avarage age was 30.1± 5.5 (18-45) and pregnancy rate was %46.5. When the cases were classified as pregnant and non pregnant and evaluated, maximum E2 level in pregnants were observed as significantly higher on the day of hCG application (p=0.03<0.05). When we classified the cases according to their endometrial thickness, %10.3 case range between 1-7mm, %87.3 case range between 7.1-14mm and %2.4 is 14+. When we classified the cases according to their ages, 248 of them (%56.4) were 30 and below, 101 (%22.9) were between 31 and 35 and 91 of them (%20.7) were 36 and above. Statistically no significant distinction was observed when age and endometrial thickness comparison was done in subgroups’ pregnancy detection. When multiple logistic regression analysis (model R2=0.0263, p<0.001) was done, age’s effect on pregnancy detection was irrelevant (p=0.158). But, endometrial thickness’s effect was significant (p=0.01). Age and endometrial thickness, both had significant impact on pregnancy together (p=0.031). Endometrial pattern’s effect on pregnancy detection was insignificant. We observed that endometrial thickness as an important parameter affecting the success of IVF cycles. However, the same situation doesn’t apply to the endometrial pattern. Age is one of the most important factors that affecting to conceive. But when the quality of embryos given, age is not the primary factor to become pregnant.
Product Review Analysis with Ranking System Based on Transaction Id and OTP Gayathri

This system aims at product ranking by analyzing the reviews. Feedbacks are accepted only from the customers who purchased the products. This will improve the customer trust on feedbacks. SVM is used for analyzing the reviews. The prior research has reported that stability is implemented using iterative smoothing and bootstrap aggregation (bagging) approach. This paper focuses on improving the stability along with the customer trust. Customer trust is the desired property of recommendation system. This is done by authentication of OTP using Random key generation algorithm.
Personalized Therapy for Pancreatic Cancer: Challenges and Opportunities

Pancreatic Ductal Adenocarcinoma (PDAC) has one of the lowest 5-year survival rates of all cancers. Early metastatic spread and failure of standard chemotherapeutics both contribute to this statistic. Over the last decade many other cancer types have benefited from the targeted therapy revolution in which signalling networks found to be altered in cancer cells are specifically targeted. Despite an ever-growing understanding of the mutation profiles in PDAC, the vast majority of these approaches have failed for this form of malignancy. Chemotherapy, which simply targets dividing cells, remains the most effective available treatment option alongside surgery. Although targeting a broad range of tyrosine kinase receptors with erlotinib has been shown to offer a modest improvement in the 5-year survival when combined with the pyrimidine-based chemotherapeutic gemcitabine, this suggests that targeted approaches may be of benefit in at least some patients. PDAC is characterised by a long genomic tail of potentially actionable mutations but each appearing in only a small number of patients, making it difficult to show a survival benefit of a targeted therapy in an unselected group of patients. Identifying specific subpopulations based on molecular characterisation of the tumour is particularly difficult in PDAC because of problems in biospecimen acquisition; only a small proportion of patients undergo surgery and the organ is difficult to biopsy due to its location. Furthermore, PDAC is characterised by cellular heterogeneity within primary tumours and their metastases, meaning that targeted therapies may have only a transient effect, killing dominant cellular populations but leaving behind potentially even more aggressive forms of cancer cells that have unidentified (and so unexploited) molecular targets. In this review, consideration is given to overcoming the barriers of personalised medicine specific to PDAC with the aim of improving the 5-year survival rates.
of Local Descriptor in RGB-D Object Recognition

The emergence of an RGB-D (Red-Green-Blue-Depth) sensor which is capable of providing depth and RGB images gives hope to the computer vision community. Moreover, the use of local features began to increase over the last few years and has shown impressive results, especially in the field of object recognition. This article attempts to provide a survey of the recent technical achievements in this area of research. We review the use of local descriptors as the feature representation which is extracted from RGB-D images, in instances and category-level object recognition. We also highlight the involvement of depth images and how they can be combined with RGB images in constructing a local descriptor. Three different approaches are used in involving depth images into compact feature representation, that is classical approach using distribution based, kernel-trick, and feature learning. In this article, we show that the involvement of depth data successfully improves the accuracy of object recognition.
Preface : Are Large Regional or Special Topic Servers Necessary ?

The main question addressed in this special issue consisting of 10 papers is this. Can powerful search engines, in combination with large information servers like Wikipedia and some very specialized smaller servers satisfy the need to provide information for all instances when special regions, interests or topics are to be served. As it turns out, the answer is a clear no.
Research on intrusion detection algorithm for wireless sensor networks

With the gradual development of MEMS technology and the growth of network technology and communication bandwidth, the Internet of Things (IoT) has become the research favorite in the field of information technology nowadays. The sensor network, which integrates the three technologies of sensor, micro-electromechanical system and network, is a new information acquisition and processing technology. In the Internet of things technology to play the role of the information transmission expressway, although the Internet of things technology to achieve the interconnection of everything, but also triggered the advent of the era of big data, but in the massive data generation, data security has become an urgent problem to solve, and whether there is wireless sensor network information intrusion is also the focus of the research field. Based on the brief introduction of sensor network architecture, this paper analyzes and forecasts an intrusion detection algorithm in a valuable application field.
Reef shallowing is a critical control on benthic foraminiferal assemblage composition on nearshore turbid coral reefs

Declining water quality represents a major threat to the coral reefs of Australia's Great Barrier Reef (GBR). Due to their close proximity to river point sources, reefs situated on the inner-shelf of the GBR are widely perceived to be most susceptible to the increased discharge of nutrients and sediments from coastal catchments, many of which have been modified since European settlement. However, the impact and magnitude of water quality change on the GBR's inner-shelf reefs remains unclear. Much of the uncertainty can be attributed to a paucity of long-term records with which to assess ecological and environmental change over appropriate reef-building timescales. Here, we present benthic foraminiferal palaeo-records from three proximal nearshore turbid-zone reefs located within the central region of the GBR. Bayesian age-depth modelling was used to identify the core intervals corresponding to the timing of European settlement in the region (c. 1850 CE), enabling the investigation of: (1) the composition and variability of benthic foraminiferal assemblages during reef shallowing towards sea level; and (2) whether any signal of increased nutrient and sediment inputs, as the result of historical land-use change, can be discerned on the most nearshore reefs of the central GBR. Multivariate analyses identified two assemblage groups, delineated by a significant increase in the relative abundance of Pararotalia spp. up-core. Our results suggest that post-European settlement associated increases in nutrient and sediment inputs are unlikely to have driven the observed shifts in benthic foraminiferal assemblage composition. Rather, we interpret changes in the composition of benthic foraminiferal assemblages as being linked to changes in hydrodynamic energy, light availability and the carbonate content of reef-matrix sediments during reef shallowing towards sea level. Our findings support the hypothesis that nearshore turbid-zone reefs have a higher resistance to increased nutrient and sediment inputs than those located further offshore, towards the inner/mid-shelf boundary of the GBR.
Multi-Regions Texture Substitution for Image and Video

Perceptual coding should take full advantage of the results from human visual system studies. Image can be parsed into two main categories of representation: contour curve and region texture. In this paper, we introduce a multi-regions texture substitution (MRTS) algorithm for images and videos. MRTS algorithm can achieve mediumlevel-visual texture substitution through selecting the smallest region texture sample. Specifically combining with dynamic texture learning and synthesis techniques, we explore it in 2D and 3D to perform multi-regions texture substitution for video sequences. Experimental results confirm MRTS algorithm can be done successfully for images with massive textures. Compared with JPEG2000 compression, MRTS can not only get more coding gain but remain most image information people care. MRTS algorithm also can get good video reconstruction quality.
Religion and Happiness in Korean Higher Education.

The purpose of this study is to examine the relevance between religion and happiness in the aspect of Korean higher education. To review this paper logically, three research questions are addressed. First, is religion able to provide happiness for people? Second, what is the relevance between religion and happiness in the aspect of Korean higher education? Last, what are the implications of religion for happiness education in South Korean universities? In order to defend these questions, a descriptive content analysis method will be utilized with a cross cultural approach. As for the limitations of this study, religion is limited to four major religions, such as Confucianism, Buddhism, Taoism, and Christianity, which historically influencing Korean society and culture. In particular, the study is focused on The Great Learning in Confucian Classics, Dhammapada in Buddhist Sutras, Tao Te Ching in Taoist Sutras, and the Proverbs in the Old Testament in the Christian Bible. Additionally, education is mainly centered on South Korean higher education. The significance of this study is to provide not only basic theories but also useful resources regarding happiness education related to religion for educational theorists and practitioners. One of research results is that Buddhism and Christianity in contemporary Korea as two major religions not only have contributed to Korean society and culture, but have led Korean private tertiary institutions. In addition, Korean elite/higher education on the basis of religion has been a significant means to come up to the way of happiness as well as to open the door of social success.
PUPT-2597 The M-theory Archipelago

We combine supersymmetric localization results and the numerical conformal bootstrap technique to study the 3d maximally supersymmetric (N = 8) CFT on N coincident M2branes (the U(N)k × U(N)−k ABJM theory at Chern-Simons level k = 1). In particular, we perform a mixed correlator bootstrap study of the superconformal primaries of the stress tensor multiplet and of the next possible lowest-dimension half-BPS multiplet that is allowed by 3d N = 8 superconformal symmetry. Of all known 3d N = 8 SCFTs, the k = 1 ABJM theory is the only one that contains both types of multiplets in its operator spectrum. By imposing the values of the short OPE coefficients that can be computed exactly using supersymmetric localization, we are able to derive precise islands in the space of semi-short OPE coefficients for an infinite number of such coefficients. We find that these islands decrease in size with increasing N . More generally, we also analyze 3d N = 8 SCFT that contain both aforementioned multiplets in their operator spectra without inputing any additional information that is specific to ABJM theory. For such theories, we compute upper and lower bounds on the semi-short OPE coefficients as well as upper bounds on the scaling dimension of the lowest unprotected scalar operator. These latter bounds are more constraining than the analogous bounds previously derived from a single correlator bootstrap of the stress tensor multiplet. This leads us to conjecture that the U(N)2×U(N +1)−2 ABJ theory, and not the k = 1 ABJM theory, saturates the single correlator bounds. July 2019 ar X iv :1 90 7. 13 22 2v 1 [ he pth ] 3 0 Ju l 2 01 9
/ Subscribe Functionalities for Future Digital Libraries using Structured Overlay Networks

We are interested in the problem of distributed resource sharing in future digital libraries (DLs). We adopt a pure P2P architecture (illustrated in Figure 1), but our ideas can be easily modified to work in the case of hierarchical P2P networks, as in [3]. Information providers (DLs) and information consumers (users) are both represented by peers participating in a peer-to-peer (P2P) overlay network. There are two kinds of basic functionality that we expect this architecture to offer: information retrieval (IR) and publish/subscribe (pub/sub). In an IR scenario a user poses a query (e.g., “I am interested in papers on bio-informatics”) and the system returns information about matching resources. In a pub/sub scenario (also known as information filtering (IF) or selective dissemination of information (SDI)) a user posts a subscription (or profile or continuous query) to the system to receive notifications whenever certain events of interest take place (e.g., when a paper on bio-informatics becomes available). In this extended abstract we concentrate on the latter kind of functionality (pub/sub) and sketch how to provide it by extending the distributed hash table Chord [4]. Distributed Hash Tables (DHTs) are the second generation structured P2P overlay networks devised as a remedy for the known limitations of earlier P2P networks such as Napster and Gnutella. We present a set of protocols, collectively called DHTrie, that extend the Chord protocols with pub/sub functionality. We assume that resources are annotated using a well-understood attributevalue model called AWPS in [2]. Thus publications and subscriptions will also be expressed in AWPS. AWPS is based on named attributes with value free text interpreted under the Boolean and vector space (VSM) models. The query language of AWPS allows Boolean combinations of comparisons A op v, where A is an attribute, v is a text value and op is one of the operators “equals”, “contains” or “similar” (“equals” and “contains” are Boolean operators and “similar” is interpreted using the VSM or LSI model). The following is an example of a publication in AWPS: { (AUTHOR, “John Smith”), (TITLE, “Information dissemination in P2P .”), (ABSTRACT, “In this paper we show that .”) }
BIODISTRIBUTION AND DOSIMETRY OF 99 m Tc-LABELED MONOCLONAL ANTIBODY ior egf / r 3 IN PATIENTS WITH TUMORS OF EPITHELIAL ORIGIN : PRELIMINARY RESULTS

Human pharmacokinetics, biodistribution and internal radiation dosimetry to normal organs and total body of Tc-labeled monoclonal antibody ior egf/r3 was investigated following intravenous (i.v) injection in 5 patients. Following administration, blood and urine samples were collected from 4 patients up to 24 hr after injection Pharmacokinetics obtained from whole blood radioactivity showed blood disappearance described most properly by a biexponential model with a mean distribution half-life value of 0.14 ± 0.02 hr and elimination half-life value of 31.0 ± 13.6 hr . Whole body anterior and posterior scans were obtained at 10 min, 1, 3, 5 and 24 hr after injection. ROIs were drawn over the heart, liver, spleen and bladder to measure the activity in the source organs. Time-activity curves for each source organ were fitted to monoor biexponential functions by non-linear least squares regression using the flexible polyhedrals method and integrated to determine organ residence times. The mean absorbed dose to the whole body and various normal organs were then estimated from residence times and from blood and urine samples using the MIRD method. The effective dose equivalent (EDE) and effective dose (ED) were calculated. Estimates of radiation absorbed dose to normal organs in rads/mCi administered (mean ± SD, n = 4) were: whole body, 0.0185 ± 0.0023, gallbladder wall , 0.0755 ± 0.00761, spleen, 0.0637 ± 0.0167 and liver, 0.276 ± 0.029. The effective dose equivalent and effective dose estimates for adults were 0.039 ± 0.008 and 0.028 ± 0.004 rem/mCi administered
Frequency Synthesizer Based on Pulse Swallowing

This article presents a design of new principle of the fractional frequency synthesizer based on pulse swallowing. This principle can be used for spurious phase modulation suppression when pulses are periodically removed from pulse train. The new synthesizer can be used also as a universal building block in phase locked loop frequency synthesizers. The mathematical analysis and simulations of the system are also presented. Key-Words – comparator; fractional frequency synthesis; frequency divider; generator; lowpass filter; pulse removing; simulation
Membership institutions and fixation of belief : a contribution to the understanding of the detrimental effects of institutions

The contribution of institutions to economic growth or, in contrast, to stagnation and even ‘collapse’, is a central question in institutional economics. The article analyses the causalities according to which institutions generate behaviour that is detrimental to prosperity. Departing from existing explanations (e.g., dysfunctionality, ‘extraction’), it argues that institutions are composite concepts, which include forms and contents that evolve with time and contexts, and imply cascades of processes involving individual cognition and social interactions: yet certain beliefs may be subjected to processes of ‘cumulative fixation’, in contrast with refutable ones (e.g., scientific beliefs), and these processes are key mechanisms of economic stagnation. The article shows that some institutions can be related to others via sequential ordering, and that in an evolutionary perspective institutions and norms governing group membership (via, e.g., kinship, language, occupation, territory, class) constitute ‘core’ institutions: more than other institutions, these induce a cumulative fixation of beliefs and shape economic outcomes (poverty, prosperity) due to their key property, i.e. the generation of social classifications that orient individual behaviour vis-à-vis other individuals (‘we’/‘them’, ‘superiors’/‘inferiors’). When contexts (environmental, political) change, this ordering may evolve in asymmetries, where some beliefs and norms absorb or crowd-out others according to mechanisms of cumulative causation, self-reinforcement and lock-in effects. Being more ‘core’, stable, than others, membership institutions drive such evolutions due to common features: beliefs that exhibit a high degree of fixation, deontic force and non-refutability and provide high cognitive and emotional rewards, thus reinforcing incentives to adhere to them and having the greatest ability to persist whatever their economic effects.
GUIDELINES FOR THE IMPLEMENTATION OF A QUALITY MANAGEMENT SYSTEM IN INDUSTRIAL COMPANIES

This article presents an implementation guide of a quality management system based on the family of ISO 9000 standards, according to the 2015 revision of ISO 9001. In line with the literature review, the study is based on a case study on the mechatronics sector. The presented implementation guide allows managers, technicians, academics and students, a practical reflection on the implementation of a quality management system in order to obtain a competitive advantage in the increasingly globalized market, requiring to the industry a solid foundation in terms of sustainability.