Miracle-dz/UniFAR-FTUs huggingface dataset:
Pilgrims tracking and monitoring based on IoT

The pilgrimage takes place in several countries around the world. The pilgrimage includes the simultaneous movement of a huge crowd of pilgrims which leads to many challenges for the pilgrimage authorities to track, monitor, and manage the crowd to minimize the chance of overcrowding’s accidents. Therefore, there is a need for an efficient monitoring and tracking system for pilgrims. This paper proposes powerful pilgrims tracking and monitoring system based on three Internet of Things (IoT) technologies; namely: Radio Frequency Identification (RFID), ZigBee, and Internet Protocol version 6 (IPv6). In addition, it requires low-cost, low-power-consumption implementation. The proposed system can efficiently handle the pilgrimage challenges; namely: the language barrier, identifying of injured or dead pilgrims, directing lost pilgrims, knowing medical records of pilgrims, and the crowd management. Finally, another paramount characteristic of the proposed IoT-based system is allowing the authorities, the heath-givers, and the pilgrim’s family for real-time tracking and monitoring of pilgrim during the pilgrimage anytime, anywhere.
Climate scenarios and projections

The 2020 RPA Assessment includes climate change as a driver affecting natural resources on forests and rangelands in the United States. This publication describes the process used to select the scenarios, climate models, and climate projections that will be used to project renewable resource conditions 50 years into the future. Downscaled climate data selected are the MACAv2-METDATA developed by Abatzoglou and others at the University of Idaho. The dataset covers the conterminous United States at a grid size of approximately 4 km (1/24 degree) on a side. The two selected scenarios are the Representative Concentration Pathways (RCPs) 4.5 and 8.5. Three criteria were used to select the climate models: (1) identification and elimination of poor performing models based on historical climate projections, (2) restriction of selection to only one model from a modeling institution, and (3) selection of a climate model that could provide projections for both the RCP 4.5 and RCP 8.5 scenarios. Climate models and projections were selected to capture a range of future climates at the conterminous scale: least warm projection, hottest projection, driest projection, and wettest projection, and one projection that reflected the middle of these ranges. The core model projections to be used in the 2020 RPA Assessment under RCP 4.5 and RCP 8.5 are: Least Warm—MRI-CGCM3; Hot—HadGEM2-ES; Dry— IPSL-CM5A-MR; Wet—CNRM-CM5; Middle—NorESM1-M. Future climates at mid-century (2041–2070) are summarized for the conterminous United States. The data are available at the USDA Forest Service Research and Development Data Archive.
A photoreactive analog of allopregnanolone enables identification of steroid-binding sites in a nicotinic acetylcholine receptor

Many neuroactive steroids potently and allosterically modulate pentameric ligand-gated ion channels, including GABAA receptors (GABAAR) and nicotinic acetylcholine receptors (nAChRs). Allopregnanolone and its synthetic analog alphaxalone are GABAAR-positive allosteric modulators (PAMs), whereas alphaxalone and most neuroactive steroids are nAChR inhibitors. In this report, we used 11β-(p-azidotetrafluorobenzoyloxy)allopregnanolone (F4N3Bzoxy-AP), a general anesthetic and photoreactive allopregnanolone analog that is a potent GABAAR PAM, to characterize steroid-binding sites in the Torpedo α2βγδ nAChR in its native membrane environment. We found that F4N3Bzoxy-AP (IC50 = 31 μm) is 7-fold more potent than alphaxalone in inhibiting binding of the channel blocker [3H]tenocyclidine to nAChRs in the desensitized state. At 300 μm, neither steroid inhibited binding of [3H]tetracaine, a closed-state selective channel blocker, or of [3H]acetylcholine. Photolabeling identified three distinct [3H]F4N3Bzoxy-AP–binding sites in the nAChR transmembrane domain: 1) in the ion channel, identified by photolabeling in the M2 helices of βVal-261 and δVal-269 (position M2–13′); 2) at the interface between the αM1 and αM4 helices, identified by photolabeling in αM1 (αCys-222/αLeu-223); and 3) at the lipid–protein interface involving γTrp-453 (M4), a residue photolabeled by small lipophilic probes and promegestone, a steroid nAChR antagonist. Photolabeling in the ion channel and αM1 was higher in the nAChR-desensitized state than in the resting state and inhibitable by promegestone. These results directly indicate a steroid-binding site in the nAChR ion channel and identify additional steroid-binding sites also occupied by other lipophilic nAChR antagonists.
Early Clinical and Functional Outcome of Primary Total Knee Replacement with Posterior Cruciate Substituting Prosthesis for Primary Knee Osteoarthritis Using 2011 Knee Society Score

Background: Primary knee Osteoarthritis (OA) is the commonest articular disease in middle age and elderly people. Primary total knee replacement (TKR) is a known world-wide standard and definitive treatment of primary knee OA following failed adequate non-operative management. It is of clinical importance to assess the clinical and functional outcome of TKR to prognosticate the severity of primary knee OA. The new (2011) knee society scoring system (nKSS) is both surgeons and patients’ assessment tool for the treatment outcome of TKR. Study Design: Prospective interventional analytical study. Aim and Objective: The aim of the study was to determine early clinical and functional outcome of primary total knee replacement in patients with primary knee osteoarthritis using nKSS. The objectives were: 1) To determine the pre-operative nKSS and post operative nKSS; 2) To determine relationships between pre-operative nKSS and post operative nKSS at 6 weeks, 3, 6, 9 and 12 months; 3) To determine the complication rates in patients undergoing primary TKR in the study centre. Methods: A prospective interventional study of 59 patients aged 51 to 70 years who had 67 Total Knee Replacements (TKRs) participated in the study between November 2015 to June 2018 at National Orthopaedics Hospital, Lagos, Nigeria. Patients’ sociodemographic data, pre-operative and post-operative nKSS system were recorded at 6 weeks, 3, 6, 9 and 12 months during follow up. The data were analyzed using Statistical Package for Social Science (SPSS). Results: There were 41 females and 18 males (M:F = 1:2.3). There were total of 67 TKRs with 31 right TKRs, 20 left TKRs and 8 staged bilateral TKRs. The participants’ age ranged from 51 to 70 years with the mean age of 59.5 (±8.5) years. Four patients did not complete the study due to various reasons. The remaining 55 participants completed the study period with progressive improvement of their post-operative nKSS at 6 weeks, 3, 6, 9 and 12 months post-operatively when compared with pre-operative nKSS (P value 0.5). Conclusion: This study revealed improved early clinical and functional outcome of primary total knee replacement in primary knee osteoarthritis using nKSS in all the studied patients. There is no significant negative effect of lower pre-operative nKSS (and its components) on the post-operative nKSS outcome.
Techniques in De-Blurring Image

Images nowadays are an integral part of our lives, whether in scientific applications or social networks and where there is an image, the concept of image blurring may occur. Blurred is a major cause of image degradation and reduces image quality. Blur occurs due to air noise as well as incorrect camera setup. Along with the blur effects, the noise also spoils the captured image. Deblurring is the operation for removing blur or noise and restoring the underlying high-quality image. Blur can be different types like Motion Blur, Gaussian Blur, and Average Blur.
Evaluation of convective storms using spaceborne radars over the Indo‐Gangetic Plains and western coast of India

Monsoonal convective systems are examined using four years (2014–2017) of radar reflectivity data from the Precipitation Features (PFs) database of the Global Precipitation Measurement (GPM) Microwave Imager (GMI) and Dual Precipitation Radar (DPR). The study classifies the cumulonimbus tower (PF‐CbT) at 12 km, and intense convective clouds at both 3 km (PF‐ICC3) and 8 km (PF‐ICC8) based on PFs' reflectivity threshold at a reference height over the Indo‐Gangetic Plains (IGP) and Indian Western coastal (WG) region, including the Arabian Sea and the Western Ghats. Results show that the regional variations are more enhanced for the PF‐ICC3 clouds with high occurrence over the IGP region. In the mixed‐phase regime, the median maximum reflectivity is greater for all cloud types over the IGP region. The occurrences of 20 and 40 dBZ echo the top height > 5 km is higher in the IGP region, indicating the deep and intense convection. The aerosol–cloud interaction is examined for warm and mixed‐phase clouds. The vertical structure of aerosols shows the suppression of warm rainfall over the IGP region. However, rainfall intensity increases in mixed‐phase clouds because of the dominancy of ice processes. The significant positive (negative) correlation is observed between the echo top height and aerosol concentrations over the IGP (WG) region. The value of the novel findings clearly states the region‐specific demand for a closer examination of the radar reflectivity–aerosol interaction on regime‐dependent clouds over the IGP region as well as contrasts against other regions for similar and contrasting cloud–aerosol‐radiation interactions.
Enterovirus D68–Associated Acute Respiratory Illness — New Vaccine Surveillance Network, United States, July–October, 2017 and 2018

In the fall of 2014, an outbreak of enterovirus D68 (EV-D68)-associated acute respiratory illness (ARI) occurred in the United States (1,2); before 2014, EV-D68 was rarely reported to CDC (2,3). In the United States, reported EV-D68 detections typically peak during late summer and early fall (3). EV-D68 epidemiology is not fully understood because testing in clinical settings seldom has been available and detections are not notifiable to CDC. To better understand EV-D68 epidemiology, CDC recently established active, prospective EV-D68 surveillance among pediatric patients at seven U.S. medical centers through the New Vaccine Surveillance Network (NVSN) (4). This report details a preliminary characterization of EV-D68 testing and detections among emergency department (ED) and hospitalized patients with ARI at all NVSN sites during July 1-October 31, 2017, and the same period in 2018. Among patients with ARI who were tested, EV-D68 was detected in two patients (0.8%) in 2017 and 358 (13.9%) in 2018. Continued active, prospective surveillance of EV-D68-associated ARI is needed to better understand EV-D68 epidemiology in the United States.
Physical activity, health-related quality of life and musculoskeletal pain among students of physiotherapy and social sciences in Eastern Croatia - Cross-sectional survey.

INTRODUCTION AND OBJECTIVE Low levels of physical activity (PA) and sedentary lifestyle have become a major public health problem in developed countries, even among the young population. The aim of the study was to determine and compare physical activity levels, health-related quality of life (HRQoL) and the prevalence of musculoskeletal pain symptoms (MPS) among the students of Physiotherapy and Social Sciences. MATERIAL AND METHODS A cross-sectional survey was performed on 517 participants and included the International Physical Activity Questionnaire - Short Form, SF-36 Health Survey, and the Nordic Musculoskeletal Questionnaire. RESULTS The majority of students (61.7%) met the criteria for the category "high" PA, and 11% respondents were in the "low" category. Male students accumulated higher levels of vigorous- and moderate-intensity PA, and scored higher in the domains of general health, vitality, and social functioning, while females scored higher in mental health (p<0.05). The physical component summary score was higher for Physiotherapy students, while Social Sciences students scored higher in the mental component summary score (p<0.05). The prevalence of MPS in the last year was 80.9%, more among female and Physiotherapy students (p<0.05). A weak association was found between MPS and lower levels of total PA, moderate-intensity PA and several domains of HRQoL (p<0.05). CONCLUSIONS Students of both disciplines reported high levels of PA, but also a high prevalence of MPS which could have affected their HRQoL which was lower than in the general population. Gender differences were found in both PA levels and HRQoL, which suggests the need for the development of gender-specific preventive programmes.
Complete Genome Sequence of Brevundimonas diminuta ATCC(B) 19146

Here, we describe the complete genome sequence of the Brevundimonas diminuta ATCC(B) 19146 strain, which contains 3,375 protein-coding genes and 61 RNAs within its 3,551,819-bp-long genome. The genome consists of a circular chromosome. ABSTRACT Here, we describe the complete genome sequence of the Brevundimonas diminuta ATCC(B) 19146 strain, which contains 3,375 protein-coding genes and 61 RNAs within its 3,551,819-bp-long genome. The genome consists of a circular chromosome.
Current understanding of cortical structure and function in migraine

Objective To review and discuss the literature on the role of cortical structure and function in migraine. Discussion Structural and functional findings suggest that changes in cortical morphology and function contribute to migraine susceptibility by modulating dynamic interactions across cortical and subcortical networks. The involvement of the cortex in migraine is well established for the aura phase with the underlying phenomenon of cortical spreading depolarization, while increasing evidence suggests an important role for the cortex in perception of head pain and associated sensations. As part of trigeminovascular pain and sensory processing networks, cortical dysfunction is likely to also affect initiation of attacks. Conclusion Morphological and functional changes identified across cortical regions are likely to contribute to initiation, cyclic recurrence and chronification of migraine. Future studies are needed to address underlying mechanisms, including interactions between cortical and subcortical regions and effects of internal (e.g. genetics, gender) and external (e.g. sensory inputs, stress) modifying factors, as well as possible clinical and therapeutic implications.
A Prospective Randomized Comparison of the Efficacy of Ultrasound- vs Fluoroscopy-Guided Genicular Nerve Block for Chronic Knee Osteoarthritis.

BACKGROUND Recently, genicular nerve block and radiofrequency ablation were introduced to alleviate knee pain in patients with chronic knee osteoarthritis. Both ultrasound- and fluoroscopy-guided genicular nerve blocks have been used. However, whether one is superior to the other remains unknown. OBJECTIVES The present study compares the efficacy of ultrasound- vs fluoroscopy-guided genicular nerve blocks. STUDY DESIGN This research used a prospective randomized comparison design. SETTING The study took place at a single pain clinic within a tertiary medical center in Seoul, Republic of Korea. METHODS From July 2015 to September 2017, a randomized controlled study was performed to analyze the difference in the efficacy of ultrasound- vs fluoroscopy-guided genicular nerve blocks. The Numeric Rating Scale (NRS-11), Western Ontario and McMaster Universities Arthritis Index (WOMAC), Global Perceived Effect Scales (GPES), and complications were evaluated pre-procedure, and 1 and 3 months after genicular nerve block. RESULTS A total of 80 patients were enrolled and randomly distributed to groups U (ultrasound-guided, n = 40) and F (fluoroscopy-guided, n = 40). Those who were lost to follow-up or had undergone other interventions were excluded, resulting in 31 and 30 patients in groups U and F, respectively. No differences in NRS-11 or WOMAC were observed between the 2 groups at baseline or during the follow-up period. GPES and complication rates were also similar between both groups. LIMITATIONS We were unable to perform double-blind randomization and did not evaluate patients' baseline emotional states. CONCLUSIONS Pain relief, functional improvement, and safety were similar between groups receiving ultrasound- and fluoroscopy-guided genicular nerve blocks. Therefore, either of the 2 imaging devices may be utilized during a genicular nerve block for chronic knee pain relief. However, considering radiation exposure, ultrasound guidance may be superior to fluoroscopic guidance.The study protocol was approved by our institutional review board (2015-0369), and written informed consent was obtained from all patients. The trial was registered with the Clinical Research Information Service (KCT 0002846). This work was presented in part as D-H Kim's MS thesis at the University of Ulsan College of Medicine (2018). KEY WORDS Genicular nerve block, ultrasound, fluoroscopy, knee osteoarthritis, Numeric Rating Scale, The Western Ontario and McMaster Universities Osteoarthritis Index.
Mathematical model for dynamic characteristics of automatic electrohydraulic drive for technological equipment

The paper is devoted to the development mathematical model of automatic rotary motion electrohydraulic drive for technological equipment and structural scheme of mathematical model for drive as object of automatic control. The hydraulic drive of rotary motion with volume regulation is considered. The drive contains regulated pump and unregulated hydraulic motor. The regulation of the working volume of the pump is carried out by the electrohydraulic amplifier. The transfer function of the regulating process of the pump working volume is represented by aperiodic link of the first order. The adequacy of mathematical model for dynamic characteristics of electrohydraulic drive has been confirmed experimentally by the Fisher criterion. To verify the adequacy, we compared the experimental and calculated transient processes for the shaft angular rotation velocity of hydraulic motor when applying the control signal. The mathematical model of automatic rotary motion electrohydraulic drive for technological equipment as object of automatic control was used as basis for further research on the synthesis of automatic control systems for equipment.
Automation and artificial intelligence in the clinical laboratory

Abstract The daily operation of clinical laboratories will be drastically impacted by two disruptive technologies: automation and artificial intelligence (the development and use of computer systems able to perform tasks that normally require human intelligence). These technologies will also expand the scope of laboratory medicine. Automation will result in increased efficiency but will require changes to laboratory infrastructure and a shift in workforce training requirements. The application of artificial intelligence to large clinical datasets generated through increased automation will lead to the development of new diagnostic and prognostic models. Together, automation and artificial intelligence will support the move to personalized medicine. Changes in pathology and clinical doctoral scientist training will be necessary to fully participate in these changes. KEYWORDS: Automation; artificial intelligence; deep learning; laboratory medicine
Coffee consumption and colorectal cancer risk: a dose-response meta-analysis on prospective cohort studies

Abstract Evidence regarding the influence of coffee drinking on colorectal cancer (CRC) is limited, and it remains unclear whether coffee consumption is associated with the risk of the disease. To clarify this association, a comprehensive meta-analysis was performed. The risk of CRC was compared between the categories of coffee consumption, and a dose-response relationship was studied using restricted cubic splines. We did not find evidence for the association between coffee consumption and CRC risk. Among alternative study inclusions, when using pooled projects, coffee consumption was related with a decreased risk of colon cancer in a subgroup analysis of never-smokers and in Asian countries, and with an increased risk of rectal cancer in an analysis of the general population and after restriction to women, never-smokers, and European countries. In conclusion, the association between coffee consumption and CRC risk is controversial and should be clarified in further cohort studies.
The Effect of Comedy Films on Postoperative Pain and Anxiety in Surgical Oncology Patients

Objectives: To determine the effect of watching Turkish comedy films on postoperative pain and anxiety in oncology surgical patients. Design: This study was conducted using a pre- and post-test randomized controlled trial model. Materials and Methods: The study was conducted in a general surgery clinic of a hospital in eastern Turkey between January 2016 and January 2017. The sample of the study consisted of 88 patients (44 test, 44 control) selected by using the randomized sampling method. In the experimental group, funny videos from Turkish old comedy movies were watched for 10 min before surgery. Anxiety, measured by the State-Trait Anxiety Inventory, and vital signs were measured before and after the experimental protocol. In the analysis of the data, descriptive statistics, χ2 and t test were used. Results: The state-trait anxiety pre- and post-test mean score of the experimental group was found to be 39.59 ± 3.66 and 37.54 ± 3.52 before and after watching the video, respectively, indicating a statistically significant difference between these two values (p ≤ 0.05). No statistically significant difference was found between the pre- and post-test state-trait anxiety scores of the patients in the control group. The decrease from the pre- to post-test mean pain score was determined as 0.65 ± 1.05 in the experimental group and 0.11 ± 0.96 in the control group. A statistically significant difference was found between the groups’ post-test mean pain scores (p ≤ 0.05). Conclusion: The study results suggest that watching Turkish comedy movie videos has a positive effect on postoperative pain and anxiety in surgical oncology patients.
Impact Profit When Implementation of International Financial Reporting Standards (IFRS)

Objective: The purpose of the study the implementation of the International Financial Reporting Standards (IFRS) regarding Investment, Property company profit after the adoption of International Financial Reporting Standards (IFRS) regarding Investment Property and analysis of application of IFRS on Property Investment to increase company profits. Then what will be investigated is the valuation of investment properties using the fair value model and the difference between the profit balance before tax and operating income. Methodology: The study examines financial statement observation, within 2010-2015 financial statements from PT. Astra International Tbk. using descriptive statistics, correlation and regression analyses. Results: It is found of the study prove how an increase in property value is obtained by an increase in corporate profits after the application of the International Financial Statements
Aflatoxin M1 Contamination in Fluid Milk Products, in Khartoum State, Sudan

In this study the aim is to investigate aflatoxin M1 (AFM1) contamination levels in fluid milks offered for sale in Khartoum State, Sudan. Different milk samples were analyzed by aflasensor kits, using screening method; about 25 samples from raw and 62 samples of processed milk from 3 factories; 40 UHT, 12 flavored UHT and 10 pasteurized milk. The results showed that 85.06% of milk samples were contamination with aflatoxin M1 at higher levels than those set by European Commission and Codex Alimentarius. High prevalence (88.7%) of aflatoxin M1 was detected in flavored, pasteurized and UHT revealed 100%, 100% and 82%, respectively and the raw milk showed 92%. In conclusion this study suggested that the presence of high contamination of AFM1 in the samples of fluid milk products could constituted possible risk hazards for human health. Therefore, imposing regulatory limits is needed for Sudan.