Miracle-dz/UniFAR-FTUs huggingface dataset:
A comparison of on-board chargers for electric vehicles with variable DC-link voltage

This paper compares two 3.3 kW on-board chargers for electric vehicles (EV) with variable DC-link voltage. The chargers consist of a bridgeless interleaved boost or buck-boost power factor correction (PFC) rectifier and an isolating DC-DC converter formed by a series resonant converter. Since the output voltage is controlled by the PFC rectifier, the voltage ratio of the DC-DC stage can be constant. Switching losses of semiconductors were measured in order to improve accuracy of losses estimation. Simulation results show better performance for the version with buck-boost PFC rectifier.
Child rearing and personality development in the Philippines

The authors of Child Rearing and Personality Development in the Philippines state that the purpose of their book is "to describe the patterns of relationships between Philippine mothers and their children, to compare these data with American findings, and to examine the results to see if they shed any light on the problems of personality formation in both Philippine and American cultures. " In this study of Filipino personality formation, "The authors have attempted to combine the questions and observations of a newcomer with the insights of a member of the society. " Guthrie and Jacobs assert that "Almost all of the theorizing and research in the domain of personality theory has been done with, or influenced greatly by studies of, disturbed persons. " Of the various conceptual systems for investigating personality development, they chose to follow H. S. Sullivan. "We feel that, in seeking to account for personality organization and personality changes, it is more productive to consider role definitions which are shared and communicated than to utilize concepts of projective systems and related instinctual and acquired unconscious processes and forces" (p. 10). Understandably, the culture concept assumes more importance for them than is typical of many psychologists.
The Essential ATP-binding Cassette Protein RLI1 Functions in Translation by Promoting Preinitiation Complex Assembly*♦

RLI1 is an essential yeast protein closely related in sequence to two soluble members of the ATP-binding cassette family of proteins that interact with ribosomes and function in translation elongation (YEF3) or translational control (GCN20). We show that affinity-tagged RLI1 co-purifies with eukaryotic translation initiation factor 3 (eIF3), eIF5, and eIF2, but not with other translation initiation factors or with translation elongation or termination factors. RLI1 is associated with 40 S ribosomal subunits in vivo, but it can interact with eIF3 and -5 independently of ribosomes. Depletion of RLI1 in vivo leads to cessation of growth, a lower polysome content, and decreased average polysome size. There was also a marked reduction in 40 S-bound eIF2 and eIF1, consistent with an important role for RLI1 in assembly of 43 S preinitiation complexes in vivo. Mutations of conserved residues in RLI1 expected to function in ATP hydrolysis were lethal. A mutation in the second ATP-binding cassette domain of RLI1 had a dominant negative phenotype, decreasing the rate of translation initiation in vivo, and the mutant protein inhibited translation of a luciferase mRNA reporter in wild-type cell extracts. These findings are consistent with a direct role for the ATP-binding cassettes of RLI1 in translation initiation. RLI1-depleted cells exhibit a deficit in free 60 S ribosomal subunits, and RLI1-green fluorescent protein was found in both the nucleus and cytoplasm of living cells. Thus, RLI1 may have dual functions in translation initiation and ribosome biogenesis.
Differential subcellular distribution of rat prostatic steroid 5alpha-reductase isozyme activities.

The rat prostate, a classical androgen-target tissue, contains both known isozymes of steroid 5alpha-reductase. i.e. type I and type II. So far, the role of the type I isozyme has been proposed as catabolic. The abundant expression of type I 5alpha-reductase in an androgen-target tissue is therefore puzzling. Assessment of the subcellular localization of 5alpha-reductase isozymes in rat prostate might contribute in elucidating their possibly distinct roles. After obtaining crude subcellular fractions by differential centrifugation, both isozyme activities were measured at neutral pH by plotting according to Eadie-Scatchard. The observations were extended by assessment of pH-dependent velocity ratios and type II 5alpha-reductase inhibitor sensitivities in these subcellular fractions. The results indicated a preferentially--although not exclusively--nuclear localization for the type I and a predominantly microsomal localization for the type II isozyme activity in the rat prostate. In conclusion, the nuclear localization of the type I isozyme seems not to concur with its proposed catabolic role.
Electronic and molecular structures of the members of the electron transfer series [Cr(tbpy)3]n (n = 3+, 2+, 1+, 0): an X-ray absorption spectroscopic and density functional theoretical study.

The electron transfer series of complexes [Cr((t)bpy)(3)](n)(PF(6))(n) (n = 3+, 2+, 1+, 0 (1-4)) has been synthesized and the molecular structures of 1, 2, and 3 have been determined by single-crystal X-ray crystallography; the structure of 4 has been investigated using extended X-ray absorption fine structure (EXAFS) analysis. Magnetic susceptibility measurements (4-300 K) established an S = 3/2 ground state for 1, an S = 1 ground state for 2, an S = 1/2 ground state for 3, and an S = 0 ground state for 4. The electrochemistry of this series in CH(3)CN solution exhibits three reversible one-electron transfer waves. UV-vis/NIR spectra and Cr K-edge X-ray absorption spectra (XAS) are reported. The same experimental techniques have been applied for [Cr(III)(tacn)(2)]Br(3)·5H(2)O (5) and [Cr(II)(tacn)(2)]Cl(2) (6), which possess an S = 3/2 and an S = 2 ground state, respectively (tacn = 1,4,7-triazacyclononane, a tridentate, pure σ-donor ligand). The Cr K-edge XAS spectra of the corresponding complexes K(4)[Cr(II)(CN)(6)]·10H(2)O (S = 1) (7) and K(3)[Cr(III)(CN)(6)] (S = 3/2) (8) have also been recorded. All complexes have been studied computationally with density functional theory (DFT) using the B3LYP functional. The molecular and electronic structures of the anionic members of the series [Cr(bpy)(3)](1-,2-,3-) have also been calculated. It is unequivocally shown that all members of the electron transfer series 1-4 and [Cr(bpy)(3)](n) (n = 3+, 2+, 1+, 0, 1-, 2, 3-) possess a central Cr(III) ion ((t(2g))(3), S = 3/2). The three N,N'-coordinated neutral (bpy(0)) ligands in the trication 1 and [Cr(III)(bpy)(3)](3+) are one-electron reduced in a stepwise fashion to localized one, two, and three π-radical anions (bpy(•))(1-) in the dicationic, monocationic, and neutral species, respectively. Complexes 2 and [Cr(bpy)(3)](2+) cannot be described as low-spin Cr(II) species; they are in fact best described as [Cr(III)((t)bpy(•))((t)bpy(0))(2)](2+) and [Cr(III)(bpy(•))(bpy(0))(2)](2+) species. Further one-electron reductions yield one, two, and three diamagnetic (bpy(2-))(2-) dianions in the mono-, di-, and trianion. Thus, [Cr(III)(bpy(2-))(3)](3-) is a normal Werner-type Cr(III) (! ) species. In all complexes containing (bpy(•))(1-) ligands, the ligand spins are strongly antiferromagnetically coupled to the spins of the central Cr(III) ion (d(3), S(Cr) = 3/2) affording the observed ground states given above. Thus, all redox chemistry of [Cr(bpy)(3)](n) complexes is ligand-based and documents that the ligand 2,2'-bipyridine is a redox noninnocent ligand; it exists in three oxidation levels in these complexes: as N,N'-coordinated neutral (bpy(0)), monoanionic π-radical (bpy(•))(1-), and diamagnetic dianionic (bpy(2-))(2-).
Effects of Imatinib on Monocyte-Derived Dendritic Cells Are Mediated by Inhibition of Nuclear Factor-κB and Akt Signaling Pathways

Dendritic cells are the most powerful antigen-presenting cells playing a decisive role for the initiation and maintenance of primary immune responses. However, signaling pathways involved in the differentiation of these cells have not been fully determined. Imatinib is a novel tyrosine kinase inhibitor effective against Abl kinases, c-Kit, and platelet-derived growth factor receptor. Using this compound, we show that human monocyte-derived dendritic cells generated in the presence of therapeutic concentrations of imatinib show a reduced expression of CD1a, MHC class I and II, and costimulatory molecules as well as decreased secretion of chemokines and cytokines resulting in an impaired capacity of dendritic cells to elicit primary T-cell responses. Using Western blot analyses, we found that these effects are mediated by inhibition of phosphatidylinositol 3-kinase/Akt pathways and a pronounced down-regulation of nuclear localized protein levels of nuclear factor-κB family members. Importantly, using blocking antibodies and tyrosine kinase inhibitors, we show that the inhibitory effects of imatinib on dendritic cell differentiation are not mediated via platelet-derived growth factor receptor and c-Kit. Taken together, our study reveals that imatinib inhibits dendritic cell differentiation and function via Akt and nuclear factor-κB signal transduction. Importantly, we show that imatinib can inhibit the function of normal, nonmalignant cells that may result in immunosuppression of these patients.
Distributed control of unmanned aerial vehicle elastic formation with speed adaptability

For a team of unmanned aerial vehicles (UAVs) in the leader-follower type, the dynamic relative position relationships between followers and the leader are described with elastic distance vector. The desired geometric shape in formation change and maintenance is constructed via the elastic coefficient matrix of distance in the three dimensional space. In the second-order kinematics model, follower vehicles' control equation is linearized with the elastic distance vector. Furthermore, the distributed control strategy is adopted for information interaction of UAVs in the formation and the feedback control algorithm is designed for the formation elastic control. Simulation results show that this control method can effectively achieve the formation geometry shape changing and maintaining during the flight process. Moreover, the elastic distance between two adjacent vehicles can adapt to the changes of the leader vehicles' velocities, so the tracking performance is not only improved greatly but also more secure.
Use of diagnostic markers to monitor fasciolosis and gastrointestinal nematodes on an organic dairy farm

A 12-month study was conducted to assess and monitor gastrointestinal tract nematodes and liver fluke in cohorts of cattle on a Scottish organic dairy farm. Various diagnostic markers for helminth parasites of cattle from different age groups were assessed monthly from April 2007 to March 2008. First season grazing stock were subjected to significant challenge from Ostertagia ostertagi nematodes as reflected in serum pepsinogen concentrations, which rose markedly in the second half of the grazing season. In addition, plasma albumin concentrations decreased and faecal egg counts (FEC) increased moderately, indicating exposure to both O ostertagi and probably Cooperia oncophora. Second season grazing animals had a peak FEC early in the grazing period, suggestive of a potential carry-over of Ostertagia species infection (‘Type 2’) during housing. All classes of cattle showed evidence of fluke (Fasciola hepatica) infection. Adult cow exposure to O ostertagi and fluke was estimated via the use of ELISA testing to detect antibodies to O ostertagi and F hepatica and the high levels detected suggested a significant exposure response. Despite low stocking densities and sympathetic grazing management, there was a significant challenge to all grazing stock from gastrointestinal nematodes and liver fluke.
Significance and assessment of coronary microvascular dysfunction

The endothelium, although only a monolayer of cells, plays a pivotal role in vascular haemostasis by regulating vascular tone, thereby controlling blood flow to end organs.1 It also plays important roles in maintaining balance between anti- and pro-coagulant activities, contributing to thrombo-resistance and controlling cellular adhesion, underlying smooth muscle proliferation, and vessel wall inflammation. In addition to local conversion of angiotensin I to angiotensin II, endothelial cells produce and release a number of vasoactive substances, including nitric oxide, endothelium derived hyperpolarising factor, prostacyclin, endothelin, and vasoconstrictor prostanoids, that regulate vascular tone. Endothelial cells can also respond to circulating vasoactive substances such as bradykinins, serotonin, adenosine, and thrombin. Alterations in endothelial function precede the development of atherosclerotic changes in larger blood vessels, which are the common underlying pathogenetic mechanisms of a large number of diseases affecting all major organs. Endothelial dysfunction should actually be considered as endothelial activation, where there is a switch from nitric oxide mediated vasodilatation and silencing of cellular processes to activation by redox signalling. Prolonged and repeated exposure to vascular risk factors may eventually overwhelm the anti-inflammatory, vasodilatory and antiproliferative effects of normal endothelium and lead to endothelial activation and dysfunction, ultimately leading to loss of endothelial cell integrity, apoptosis and their release into the circulation. Changes in the microvasculature, through its pivotal roles in initiating and perpetuating atherosclerotic diseases in the larger conduit vessels, play an important part in the end organ damage from vascular diseases. Understanding the importance of the endothelium in health and disease not only affords the opportunity for early detection of diseases in at-risk patients, but also provides a means for risk stratification, development of interventions to prevent disease progression and to alleviate diseases subsequent in the pathophysiological process, and the development of novel techniques to assess response to treatment. It …
Familial cases of HTLV‐I—associated myelopathy

We studied two familial cases of human T‐lymphotropic virus type I (HTLV‐I)—associated myelopathy from the Kii Peninsula, an area of endemic adult T‐cell leukemia‐lymphoma (ATLL) in Japan. Incidence of familial clustering of HTLV‐I—associated myelopathy was about 20%. Type C retrovirus was isolated from cultured cerebrospinal fluid and peripheral blood lymphocytes in both cases. Modes of transmission seem to be similar to those described in ATLL, although there are no reports of both HTLV‐I—associated myelopathy and ATLL occurring in the same family. We suggest three possibilities: (1) that the virus associated with HTLV‐I—associated myelopathy is different from the virus causing ATLL, although they seem to be morphologically and immunologically similar; (2) that HTLV‐I—associated myelopathy may be determined by the ATLL‐causing virus plus a specific genetic background; and (3) some combination of factors 1 and 2.
A ETNOBOTÂNICA E AS PLANTAS USADAS COMO REMÉDIO NA COMUNIDADE BOM JARDIM, MT, BRASIL

RESUMO - (A Etnobotânica e as plantas usadas como remedio na Comunidade Bom Jardim, MT, Brasil). O estudo foi realizado na comunidade Bom Jardim com o objetivo de resgatar o conhecimento que as pessoas possuem das plantas como remedio, modo de uso, o quanto as utilizam e a finalidade. Aplicou-se o pre-teste, entrevista semi-estruturada e observacao direta abordando o uso, a preparacao da planta e a indicacao das mesmas. A coleta dos dados foi de outubro de 2006 a julho de 2007. O material botânico encontra-se no Herbario Central da UFMT. Dos entrevistados 45% nao apresentam escolaridade, numa faixa etaria de 20 a 89 anos de idade. Citaram 86 especies distribuidas em 45 familias, mais expressivas Fabaceae, Mimosaceae, Caesalpiniaceae. Habito arboreo, seguido de herbaceo e arbustivo. A folha e a parte mais utilizada e o principal modo de preparo e o cha. A populacao demonstrou ter conhecimento e fazer uso das plantas locais e revelaram um largo consumo na categoria de uso medicinal. O cuidado com a diversidade vegetal e o processo de conservacao ficou evidente na fala e no manejo que as pessoas dispensam as atividades do seu cotidiano. Palavras-chave: etnobotânica, plantas medicinais, fitoterapia
Smart Power Devices and ICs Using GaAs and Wide and Extreme Bandgap Semiconductors

We evaluate and compare the performance and potential of GaAs and of wide and extreme bandgap semiconductors (SiC, GaN, Ga2O3, and diamond), relative to silicon, for power electronics applications. We examine their device structures and associated materials/process technologies and selectively review the recent experimental demonstrations of high voltage power devices and IC structures of these semiconductors. We discuss the technical obstacles that still need to be addressed and overcome before large-scale commercialization commences.
Perfil de Resistência e Virulência Enterococcus spp Isolado de Rede de Abastecimento de Água de Londrina – PR

RESUMO Na agua os Enterococcus spp. podem ser encontrados como contaminantes, principalmente em razao do crescimento populacional em regioes hidricas. O presente estudo teve como objetivo analisar a incidencia de fatores de virulencia e resistencia entre isolados de Enterococcus spp. do Ribeirao Cambe na cidade de Londrina-PR. Para tanto, foi realizado o perfil fenotipico por meio das tecnicas de coloracao de Gram, teste de catalase e suscetibilidade a antimicrobianos e perfil genotipico por meio da tecnica de PCR com a identificacao dos isolados a nivel de genero e especie. Todos os 22 isolados obtidos sao pertencentes ao genero Enterococcus, destes 10 foram identificados como pertencentes a especie E. faecium enquanto que 12 foram identificados como Enterococcus spp.onde o maior numero de isolados resistentes foi observado frente a Tetraciclina (TET 30μg) e o maior nivel de sensibilidade foram frente a Vancomicina (VAN 30μg).
Involvement of the histidine protein (HPr) of the phosphotransferase system in chemotactic signaling of Escherichia coli K-12

It is known that in mutants of Escherichia coli lacking the histidine protein (HPr) of the carbohydrate: phosphotransferase system, all substrates of the system can be taken up in the presence of the fructose-regulated HPr-like protein FPr (gene fruF). Although this protein fully substituted for HPr in transport and phosphorylation, we found that it was not able to complement efficiently for HPr in mediating chemotaxis toward phosphotransferase system substrates. Furthermore, transport activity and chemotaxis could be genetically dissected by the exchange of single amino acids in HPr. The results suggest a specific role of HPr in chemotactic signaling. We propose a possible link of signal transduction pathways for phosphotransferase system- and methyl chemotaxis protein-dependent substrates via HPr.
Laryngeal Pathologies Analysis Using Glottal Source Features

This experimental study looks at the problem of pathological disorders analysis from speech signals. Knowing that the vocal tract pathologies provide acoustic changes commonly called dysphonia. In particular, laryngeal pathologies have an effect on the larynx and vocal cords. When regarding to the speech production model, source-filter, the impact is even more apparent in the glottal source. Our study reports on : firstly, the estimation of the glottal source where the accurate estimation is considered. Secondly, parameterization of the glottal source. Many features are extracted such as normalized amplitude quotient (NAQ), difference between harmonic H1H2, peak slop . This analysis is performed around the German database which contains many recordings (normal and pathological subjects). More than 50 subjects are used where each speaker pronounce the sustained vowel [a] in normal intonation. The extracted parameters show an interesting tool for the discrimination between normal and pathological voice. In particular, the peak slop and harmonic richness factor present a significant differences. This work is developed under Matlab thanks to the project COVAREP (A Collaborative Voice Analysis Repository for speech technologies).
Effects of Juvenile Hormone Analogues (JHA) on the Development of Trypanosoma cruzi

Juvenile hormone analogues were tested for their lytic activity on Trypanosoma cruzi Chagas, 1909 blood tripomastigotes cultivated in vitro. The results indicated that the carbamate 4 and the phenoxyphenol derivative 1 are considered good candidates for blood sterilization. The compounds were also assayed for inhibition of development of parasites in infected mice showing a moderated degree of activity.
Multitask Relative Similarity Learning

Relative similarity learning (RSL) aims to learn similarity functions from data with relative constraints. Most previous algorithms developed for RSL are batch-based learning approaches which suffer from poor scalability when dealing with realworld data arriving sequentially. These methods are often designed to learn a single similarity function for a specific task. Therefore, they may be sub-optimal to solve multiple task learning problems. To overcome these limitations, we propose a scalable RSL framework named OMTRSL (Online Multi-Task Relative Similarity Learning). Specifically, we first develop a simple yet effective online learning algorithm for multi-task relative similarity learning. Then, we also propose an active learning algorithm to save the labeling cost. The proposed algorithms not only enjoy theoretical guarantee, but also show high efficacy and efficiency in extensive experiments on real-world datasets.
Neutron scattering from a collective spin fluctuation mode in a CuO2 bilayer.

A resonance in the magnetic scattering of neutrons from superconducting ${\mathrm{YBa}}_{2}$${\mathrm{Cu}}_{3}$${\mathrm{O}}_{7}$ has been observed at a momentum transfer of (\ensuremath{\pi}/a,\ensuremath{\pi}/a,\ensuremath{\pi}/c\ifmmode\bar\else\textasciimacron\fi{}), where a is the in-plane Cu spacing and c\ifmmode\bar\else\textasciimacron\fi{} is the Cu-Cu bilayer spacing. Here we construct a model of a ${\mathrm{CuO}}_{2}$ bilayer and show that a collective S=1, antiferromagnetic excitation with q=(\ensuremath{\pi}/a,\ensuremath{\pi}/a,\ensuremath{\pi}/c\ifmmode\bar\else\textasciimacron\fi{}) arises if the gap has ${\mathit{d}}_{{\mathit{x}}^{2}\mathrm{\ensuremath{-}}{\mathit{y}}^{2}}$ symmetry. \textcopyright{} 1996 The American Physical Society.