Miracle-dz/UniFAR-FTUs huggingface dataset:
Relationship between emotional eating and coping with stress of nursing students.

PURPOSE This research aims to determine the relationship between the coping skills and emotional eating habits of young adults. DESIGN AND METHODS The population consisted of 473 nursing students whom registered in the Faculty of Health Sciences at a state university in Turkey during 2018 and 2019 education terms. Data were collected through the Demographic Form, Turkish Emotional Eating Scale (TEES), and Coping Style Scale (CSS). FINDINGS "Eating in anxiety" (r = -.174; P = .000) and "eating in the negative mood" (r = -.123; P = .007) subscale scores of TEES showed a statistically significant, negative correlation with the "self-confident approach" subscale score of CSS. PRACTICE IMPLICATIONS In light of the data, it is suggested to increase the frequency of psychological counseling offered for these students and setup behavior change training either an individual or group settings. Besides, the conjoint effort of health professionals and psychiatric nurses would be highly beneficial for the development of effective assessment tools to determine students at risk and engage in appropriate prevention strategies such as training programs that would have a direct impact on the students' habitual diet. Subsequent research is recommended incorporating additional variables such as body perception, ideal female image, expectations of perfection toward the body, and self-worth defined thru the body.
Revealing the Invisible Emotion Work of Caregivers: A Photovoice Exploration of Informal Care Provided by Family Caregivers for Post-9/11 Veterans With Traumatic Brain Injuries

Objective: Describe the different forms of emotion work performed by family caregivers of veterans living with a traumatic brain injury (TBI). Design: Collaborators were provided cameras to take photographs illustrating their experiences as family caregivers. The meaning behind caregiver photographs was solicited using photoelicitation interviews and coded. Setting: Homes of veterans or other informal settings in 2 regions of the United States served by the Southeast Louisiana Veterans Health Care System and the Veterans Affairs Portland Health Care System. Participants: Twenty-six family caregivers of post-9/11 era veterans with TBI. Results: Caregivers described performing different types of intangible, and largely invisible, work centered on emotion management. Emotion work primarily involved creating a new normal, keeping things calm, and suppressing their own emotional experiences to “put on a brave face. ” Although having derived a sense of satisfaction and identity from their role, caregivers acknowledged that emotion work was challenging and sometimes stressful. The Photovoice method allowed caregivers to express through metaphor experiences that otherwise would have been hard to articulate and share with others. Conclusion: Findings signal a need for healthcare systems and providers to acknowledge emotion work as a potential source of stress and to provide multifaceted support for veterans and family caregivers.
Multifunctional Natural Polymer Nanoparticles as Antifibrotic Gene Carriers for CKD Therapy.

BACKGROUND Progressive fibrosis is the underlying pathophysiological process of CKD, and targeted prevention or reversal of the profibrotic cell phenotype is an important goal in developing therapeutics for CKD. Nanoparticles offer new ways to deliver antifibrotic therapies to damaged tissues and resident cells to limit manifestation of the profibrotic phenotype. METHODS We focused on delivering plasmid DNA expressing bone morphogenetic protein 7 (BMP7) or hepatocyte growth factor (HGF)-NK1 (HGF/NK1) by encapsulation within chitosan nanoparticles coated with hyaluronan, to safely administer multifunctional nanoparticles containing the plasmid DNA to the kidneys for localized and sustained expression of antifibrotic factors. We characterized and evaluated nanoparticles in vitro for biocompatibility and antifibrotic function. To assess antifibrotic activity in vivo, we used noninvasive delivery to unilateral ureteral obstruction mouse models of CKD. RESULTS Synthesis of hyaluronan-coated chitosan nanoparticles containing plasmid DNA expressing either BMP7 or NGF/NKI resulted in consistently sized nanoparticles, which-following endocytosis driven by CD44+ cells-promoted cellular growth and inhibited fibrotic gene expression in vitro. Intravenous tail injection of these nanoparticles resulted in approximately 40%-45% of gene uptake in kidneys in vivo. The nanoparticles attenuated the development of fibrosis and rescued renal function in unilateral ureteral obstruction mouse models of CKD. Gene delivery of BMP7 reversed the progression of fibrosis and regenerated tubules, whereas delivery of HGF/NK1 halted CKD progression by eliminating collagen fiber deposition. CONCLUSIONS Nanoparticle delivery of HGF/NK1 conveyed potent antifibrotic and proregenerative effects. Overall, this research provided the proof of concept on which to base future investigations for enhanced targeting and transfection of therapeutic genes to kidney tissues, and an avenue toward treatment of CKD.
Linking Policy Research and Practice in ‘Stig Systems’: Many Obstacles, But Some Ways Forward

This paper reflects on the relevance of systems thinking about the interdependent policy issues bearing on the dynamics of science, technology and innovation in their relationship to economic growth. Considering the approach that characterizes much of the current economics literatures treatment of technology and growth policies, we pose the critical question: what kind of systems paradigm is likely to prove particularly fruitful in that particular problem-domain: Evolutionary, neo-Schumpeterian, and complex system dynamics approaches are conceptually attractive and we analyze their respective virtues while also acknowledging their more serious problematic features. Those become visible quickly when trying connect systems-relevant research with practical policy-making in this field. Not content to have simply identified some significant obstructions in the path toward that goal, the paper also suggests some potentially feasible ways forward.
Investigation of HotSpots in TomoDirect 3 DCRT Breast Treatment

Background: Conventional tomotherapy platforms only allow for the delivery of helical IMRT. However the use of IMRT and helical delivery in breast cancer treatment is non-standard. Newer tomotherapy units are equipped with a static-beam mode with 3DCRT capabilities. During the clinical use, we frequently observe hot-spots in the plan that renders the plan clinically unacceptable. The purpose of this study is to investigate the underlying cause of the hot-spots in tomotherapy static-beam breast treatment and possible solutions. Materials/Methods: Theories about the formation of the hot-spot were developed. Eight lumpectomy patients contoured according to RTOG-1005 specifications were also used to illustrate the magnitude of hot-spots under various planning strategies. Two tangential beams were used for the whole breast irradiation plan with prescription dose of 40 Gy in 15 fractions. Results: The hot-spot was identified as the behavior of the optimization engine when part of the target region was blocked. With the current design of tomotherapy’s 3DCRT planning where user adjustment was greatly limited, none of the planning strategies were able to reduce the hot-spots to acceptable levels in the eight patients studied. The best strategy still produced an average of 48.5 Gy (121% of prescription dose) hot-spot dose and 30.4 cc hot-spot volume (volume receiving > 110% prescription dose). It is also shown that the hot-spot was not a result of energy or other physical limitation of the radiation device. By manually adjusting the plan sinogram, the maximum hot-spot dose drops from 121% to 111% and the hot-spot volume drops from 30 cc to 6 cc on average. Conclusions: While TomoDirect 3DCRT showed great promise in breast treatment, treatment planning software improvements may be needed in order to improve the clinical acceptability by reducing hot-spots in normal tissue. How to cite this paper: Chen, Q. , Mallory, M. , Crandley, E. and Khandelwal, S. (2018) Investigation of Hot-Spots in TomoDirect 3DCRT Breast Treatment. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, 7, 376-390. https://doi.org/10.4236/ijmpcero.2018. 73031 Received: June 23, 2018 Accepted: August 17, 2018 Published: August 20, 2018 Copyright © 2018 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access
Differences in Capacity of High‐Density Lipoprotein Cholesterol Efflux Between Patients With Systemic Lupus Erythematosus and Rheumatoid Arthritis

Cholesterol efflux capacity (CEC) is the ability of high‐density lipoprotein (HDL) cholesterol to accept cholesterol from macrophages. Lipid profiles and CEC appear to be altered in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) due to disease activity and inflammation. CEC has been linked to cardiovascular events in the general population and to subclinical atherosclerosis in SLE and RA patients. The aim of this study was to establish whether CEC varies between patients with SLE and those with RA.
The combined effect of dietary supplement “Leptin Manager” and power fitness exercises on weight loss in women with different LEPR (rs1137101) genotypes

The combined effect of dietary supplement “Leptin Manager” and power fitness exercises on weight loss in women with different LEPR (rs1137101) genotypes Prof. Dr. Svitlana Drozdovska1, Assoc. Prof. Oxana Palladina1, Anna Polishchuk1, Sergiy Yuriev2 National University of Physical Education and Sport of Ukraine, Ukraine1 Department of General and Molecular Pathophysiology, Bogomoletz Institute of Physiology, National Academy of Science, Ukraine2
MAPRE1 promotes cell cycle progression of hepatocellular carcinoma cells by interacting with CDK2

Targeting cyclin‐dependent kinases (CDKs) is a promising method of therapy for cancer. Unfortunately, the efficacy of CDK inhibitors in hepatocellular carcinoma (HCC) is limited, due in part to incomplete understanding of cell cycle progression and a lack of specific biomarkers to adequately identify which patients may be responsive to CDK inhibitors. In the present study, we report that microtubule‐associated protein RP/EB family member 1 (MAPRE1), a gene involved in cell cycle and microtubule regulation, is significantly increased in HCC tissue, promotes HCC cell proliferation, enhances in vitro tumorigenesis, and associates with poor prognosis of HCC. We demonstrate that MAPRE1 binds with CDK2, resulting in the hyperphosphorylation of the CDK2 Thr161 residue in HCC cells. Our findings reveal that targeting MAPRE1 might be an effective therapeutic strategy in HCC, and suggest that MAPRE1 expression might provide a promising biomarker to stratify patients with HCC who may benefit from treatment with CDK inhibitors.
Using Funds of Knowledge to Address Diversity Issues in STEM

Miner et al. (2018) call for industrial and organizational (I-O) psychologists to examine the societal structures that influence women's underrepresentation in STEM. Here we extend their ideas and suggest that diversity in STEM would benefit from considering how people develop within the context of their environment. Educational researchers refer to the knowledge people develop through daily experiences with their cultural milieu as funds of knowledge. Funds of knowledge essentially represent a person's expertise, and educational researchers have recognized that designing environments that draw from expertise facilitates success for students, including women and underrepresented minorities in STEM.
Impact of lockdown on rheumatology outpatient care in the age of COVID-19

We read with great interest the editorial written by McInnes1 who discussed regarding the role of the rheumatologist and the rapidly changing landscape in the practice of rheumatology brought about by the COVID-19 pandemic. European League Against Rheumatism (EULAR)2 had also recently published several recommendations for the management of rheumatic and musculoskeletal diseases when local measures of social distancing are in effect. We were interested in the impact caused by local public health measures to control the pandemic on rheumatology outpatient care at our centre. Extraordinary measures have been advocated globally to control the spread of the COVID-19 pandemic. Malaysia’s first COVID-19 case was reported on the 25 January 20203 and cases spiked in March 2020 reaching the highest number in South-East Asia in early April. Malaysia instituted a lockdown from 18 March 2020 which was extended 9 June 2020 (a 12-week period) as a public health measure to curb the pandemic.4 5 During the pandemic, our hospital was designated as a COVID-19 hybrid hospital tasked with taking in both COVID-19 and regular patients. Several hospital-wide strategies were implemented to contain the pandemic and decongest the hospital including rescheduling of non-urgent patient appointments, reducing non-essential …
Twenty years of changes in the disease assessment method of the Global Initiative for Chronic Obstructive Lung Disease

Abstract The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has been changing for nearly 20 years. GOLD has moved from single assessment using spirometry to a more comprehensive assessment of chronic obstructive pulmonary disease using spirometry, symptoms and exacerbation history. And subsequently, a new assessment system for chronic obstructive pulmonary disease separated spirometric grades from the old assessment system, and classified patients only according to their symptoms and history of exacerbation. The distribution, clinical characteristics, treatment, and prognosis of the new subgroups were different from the old ones. In this review, we will present a brief profile of changes made to the disease assessment method of GOLD, based on the relevant existing literature.
Multimodal biometric hashkey cryptography based authentication and encryption for advanced security in cloud

Cloud Computing (CC) is a technology that is growing at a faster pace, gaining much popularity with startup companies increasing and opting for clouds’ services. The growth rate of this technology is high and so is the security threat. Though there are existing authentication systems like two factor authentication, biometric based authentication and so on, hackers still pose greater challenges. Though password-based authentication system is simple, it is highly vulnerable to security breaches. Biometric based authentication has better security, but usage of single biometric traits can also be easily compromised. Thus, this research work, Multimodal Biometric Hashkey Cryptography (MBHC) brings about a novel security framework that focuses on both authentication and securing cloud data using multiple modalities. Authentication is based on multiple biometric modalities viz. Fingerprint, Iris and Face features. Features from these modalities are extracted using linear filters. Artificial Fish Swarm Algorithm (AFSA) is used for feature optimization, further to which Support Vector Machine (SVM) acts as classifier for identifying genuine users against imposters. Cryptographic keys are generated from these modalities that serve as input to Advanced Encryption Standard (AES) Algorithm for encrypting and decrypting the information stored in cloud. Integrity of data is also ensured using hash function for which the facial features and the encrypted message are the inputs. Thus, the experimental results show that the proposed architecture provides improved security for cloud computing environment when compared to the existing models.
Interactive comment on “ Viable cold-tolerant iron-reducing microorganisms in geographically-isolated subglacial environments ”

Response: The manuscript will be revised to ensure it is clear to the reader that these were enrichment-, and not culture-based methods. Indeed the potential for syntrophic relationships between different microorganisms within a mixed community is the reason for working with enrichments as opposed to attempting to isolate individuals. In our view, studying mixed communities has more relevance to the occurrence of a process in situ
The Un Oeuf study: Design, methods and baseline data from a cluster randomised controlled trial to increase child egg consumption in Burkina Faso

Abstract In many low‐income countries, such as Burkina Faso, rates of malnutrition are high among children. Research indicates that animal source foods may provide important elements to improve growth and development of young children, especially during periods of rapid development, such as the first 1,000 days of life. The Un Oeuf study is designed to test an innovative behaviour change communication strategy to increase egg consumption in children 6–24 months in Burkina Faso, thereby improving dietary diversity and nutritional outcomes. This 1‐year cluster randomised controlled trial tests whether the gifting of chickens by a community champion directly to a child, combined with a behaviour change package of integrated poultry management and human nutrition trainings, can significantly increase egg consumption among children under 2 years in rural communities where egg consumption is very low. The nutrition‐sensitive behaviour change package is designed to increase egg consumption through improving livestock production, women's empowerment and food security at the household level. This paper presents a detailed account of the study design and protocol for the Un Oeuf study, alongside a description of the study population. Baseline data show a study population with high rates of malnutrition (stunting 21.6%, wasting 10.8% and underweight 20.4%) and a very low rate of egg consumption—less than 10% among children. Although poultry production is quite common, egg consumption is low reportedly because of cultural norms, including widespread practice of allowing eggs to hatch and a lack of knowledge about the nutritional benefits of egg consumption.
A mathematical model adapted to a P swarm to detect malevolent actions

Robotic swarms could solve, without the need for a central controller, a wide range of difficult applications in real-world environments. In the first part of paper is extended the notion of a P colony to a colony of P colonies used for robotic swarms, called P swarms. The second part of our research is based on the basic principles of NSAs (negative selection algorithms, in AIS field) to develop an computing algorithm for Pcol automaton. In this paper we define a mathematical model bio-inspired for security issues of robotic swarms, which combining computational models with evolutive systems. M.S.C. 2010: 68N30, 68T40, 92-08, 92B20, 93C85.
Negative Attribution Bias and Related Risk Factors After Brain Injury

Objective: In participants with traumatic brain injury (TBI) and peer controls, examine (1) differences in negative attributions (interpret ambiguous behaviors negatively); (2) cognitive and emotional factors associated with negative attributions; and (3) negative attribution associations with anger responses, life satisfaction, and participation. Setting: Two TBI outpatient rehabilitation centers. Participants: Participants with complicated mild to severe TBI (n = 105) and peer controls (n = 105). Design: Cross-sectional survey study. Main Measures: Hypothetical scenarios describing ambiguous behaviors were used to assess situational anger and attributions of intent, hostility, and blame. Executive functioning, perspective taking, emotion perception and social inference, alexithymia, aggression, anxiety, depression, participation, and life satisfaction were also assessed. Results: Compared with peer controls, participants with TBI rated behaviors significantly more intentional, hostile, and blameworthy. Regression models explained a significant amount of attribution variance (25%-43%). Aggression was a significant predictor in all models; social inference was also a significant predictor of intent and hostility attributions. Negative attributions were associated with anger responses and lower life satisfaction. Conclusion: People with TBI who have higher trait aggression and poor social inferencing skills may be prone to negative interpretations of people's ambiguous actions. Negative attributions and social inferencing skills should be considered when treating anger problems after TBI.
Hybridity, diversity and the division of labour in the third sector: what can we learn from homelessness organisations in the UK?

Both nationally and across Europe, the growing preference for third sector involvement in service provision has been concomitant with an increasing emphasis on monitoring the performance of organisations that receive state funding, and the development of competitive quasi-markets amongst prospective third sector providers. These changes have not only affected individual third sector organisations (TSOs), but have also disrupted and challenged our understandings of how the third – or voluntary – sector might be defined and its boundaries delineated. The ‘blurring’ of the boundaries between the different sectors that comprise the welfare mix is not a new phenomenon, but has arguably been accentuated through the increasing adoption by some TSOs of values and practices associated with the state and market sectors. The notion of ‘hybridity’ has consequently come to the fore as a means by which we might better understand and conceptualise the third sector.
HyperTuner: Visual Analytics for Hyperparameter Tuning by Professionals

While training a machine learning model, data scientists often need to determine some hyperparameters to set up the model. The values of hyperparameters configure the structure and other characteristics of the model and can significantly influence the training result. However, given the complexity of the model algorithms and the training processes, identifying a sweet spot in the hyperparameter space for a specific problem can be challenging. This paper characterizes user requirements for hyperparameter tuning and proposes a prototype system to provide model-agnostic support. We conducted interviews with data science practitioners in industry to collect user requirements and identify opportunities for leveraging interactive visual support. We present HyperTuner, a prototype system that supports hyperparameter search and analysis via interactive visual analytics. The design treats models as black boxes with the hyperparameters and data as inputs, and the predictions and performance metrics as outputs. We discuss our preliminary evaluation results, where the data science practitioners deem HyperTuner as useful and desired to help gain insights into the influence of hyperparameters on model performance and convergence. The design also triggered additional requirements such as involving more advanced support for automated tuning and debugging.
Title: Integration of an Inertial Navigation System and DP

The paper describes an architecture for the integration of an inertial navigation system (INS) into a dynamic positioning (DP) system. It discusses the major benefits of using INS for DP, and includes the results of sea-trials conducted to show these benefits. There are a number of possible benefits to using an INS as an input to the DP system. These benefits are dependent upon a range of factors including the operations being undertaken by the vessel, the ease of use and the quality of the equipment. One use of an INS is to supplement or clean-up measurements from an existing measurement system. By coupling the INS to a hydro-acoustic system the INS can help to reduce the noise on the measurements and fill-in for long update rates, for example, to prolong battery life for transponders.