Miracle-dz/UniFAR-FTUs huggingface dataset:
Elementary theory of L-functions and Eisenstein series

The romance of analysis and arithmetic is among the deepest and most enticing themes in all of mathematics. Though arithmetic, with all of its delicate subtleties, may at first seem an unlikely match for analysis with its powerful techniques, the relationship between the two has always been a vital one. In recent decades padic analysis—a hybrid of arithmetic and analysis—has emerged as a fascinating offspring of this union. With stunning successes in Iwasawa theory, p-adic modular forms, p-adic galois representations and their deformation theory, the field of padic analysis has forcefully asserted its own independence. Perhaps even more significantly, the p-adic theory is beginning to reveal some of the most intimate secrets of the mysterious relationship of analysis and arithmetic. Andrew Wiles’s recent proof with Richard Taylor [12], [13] of the semistable modularity conjecture— and its corollary, Fermat’s Last Theorem—is just one striking example. Among the most successful tools for the interaction of analysis and arithmetic are the Dirichlet series, i.e. infinite series of the form
ASSIST-V: An Environment Simulator for IBM 360 Systems Software Development

This paper describes ASSIST-V, a software tool designed for use in the teaching of operating systems, fie management, and machine architecture courses. ASSIST-V is a program that provides an environment for the implementation, testing, and evaluation of systems software for the IBM 360 series machines. This capability is achieved by simulating all relevant aspects of the machine's architecture. In particular, ASSIST-V simulates interrupts, I/O channels, and I/O devices, as well as all IBM 360 machine instructions. In addition, ASSIST-V provides extensive debugging and statistics-gathering aids.
Anti-DNA and Anti-Nucleosome Antibodies: an Update

Among the large spectrum of autoantibodies (Ab) detected in systemic lupus erythematosus (SLE), anti-dsDNA Ab have been used to diagnose and assess disease activity for more than 60 years. Anti-dsDNA Ab are often associated with anti-nucleosome Ab, and in clinical practice combining both is helpful for diagnosis, prognosis, and as biomarkers to monitor response to treatment, especially when using drugs that target B cells and Ab production. In general, the association of anti-dsDNA Ab plus anti-nucleosome Ab is linked with disease flares and can indicate lupus nephritis. Moreover and since anti-nucleosome Ab have higher sensitivity and specificity than anti-dsDNA Ab, the former is a useful marker in SLE patients negative for anti-dsDNA Ab and in the diagnosis of certain types of drug-induced lupus.
The predictive value of cerebrospinal fluid dynamic tests in patients with th idiopathic adult hydrocephalus syndrome.

OBJECTIVE To evaluate the predictive value of the cerebrospinal fluid (CSF) tap test and CSF outflow conductance in the selection of patients with the idiopathic adult hydrocephalus syndrome, defined exclusively on a clinical basis, for shunt surgery. DESIGN A prospective, consecutive case series. All patients were assessed before surgery and at 3 months after shunt placement. Preoperatively, CSF pressure, conductance, and CSF formation rate were assessed by a constant-pressure infusion method. Improvement in gait and cognitive functions after removal of CSF was noted (ie, with the CSF tap test). Postoperatively, the infusion method was used to evaluate shunt function. SETTING Tertiary, academic referral center. PATIENTS Thirty-five patients with idiopathic adult hydrocephalus (normal-pressure hydrocephalus) syndrome based on conservative clinical criteria. No predictive tests were used for inclusion. All patients had a typical gait disturbance and a communicating hydrocephalus. Twenty-eight patients also had dementia or incontinence, or both. INTERVENTION The CSF diversion (Cordis, [Orbis-Sigma]) valve, six patients; Hakim's standard system (Cordis Hakim standard system), 29 patients. OUTCOMES OF SURGERY: Serial videotaping of gait, a comprehensive neuropsychologic battery, and the Bartel index of activities of daily life. RESULTS Gait was improved in 25 (72%) of the 35 patients, whereas the Bartel index remained unchanged. The conditions of five of seven patients with gait disturbance as the sole symptom improved. The spatial function (37% improved) and the findings from the Fuld object memory tests (29% improved) were significantly improved. Shunt dysfunction could not explain the lack of effect of an operation in the remaining patients. It should be noted that these results obtained at 3 months postoperatively may not be applicable in a long-term perspective. The CSF outflow conductance or CSF tap test were not able to identify those patients who would or would not benefit from a CSF diversion procedure. However patients had a lower conductance and a higher CSF pressure than did control subjects. CONCLUSIONS Considerable improvement in gait was seen, but cognitive function was little affected. The CSF tap test or conductance does not provide additional information that is necessary to distinguish between patients whose conditions will or will not respond to shunting, when selection for surgery is based on conservative clinical criteria.
Developing a context-based performance measure for persons with schizophrenia: the test of grocery shopping skills.

OBJECTIVE This article describes how authenticity and directness, desired characteristics of performance measures, were applied to the development of a context-based Test of Grocery Shopping Skills (TOGSS) for persons with schizophrenia. METHOD The steps used in developing the measure included interviewing consumers with schizophrenia to identify issues in grocery shopping, conceptualizing how authenticity and directness could be applied to shopping performance, and selecting grocery items to be used in the test. The two forms of the TOGSS were administered to 26 persons with schizophrenia or schizoaffective disorders to evaluate reliability (stability, equivalence, interrater) and validity (convergent, generalizability) of the TOGSS. RESULTS The correlations between the two forms of the TOGSS over two different testing periods were significant, ranging from . 64 to . 83. Subscale scores were moderately correlated (R = .52 to .94) with a similarly constructed test of drugstore shopping. CONCLUSION A systematic method can be used to develop a context measure of performance. The TOGSS has beginning evidence of reliability and validity. With further study, the test will be useful in assessing the independent living skill of grocery shopping in persons with psychiatric disorders.
Female Victims of Police Misconduct: Ignored by Existing Narratives?

The issue of police brutality and use of force has become increasingly prevalent in both mainstream media and sociological research. However, while instances of police brutality against male citizens continue to make international headlines, female victims of police brutality fail to receive attention in both the media and scholarly research. This paper aims to answer the question of whether or not female victimization is being ignored by narratives of police misconduct. Using sociological, feminist, structural, organizational, and cultural approaches, the factors that establish the conditions for female victimization by police will be examined in detail. A variety of studies that highlight the existence of police brutality against women will also be presented and analyzed, which will then be combined with theoretical perspectives to explain the absence of women in this area of research.
The dual nature of the membrane potential increase associated with the activity of the sodium/potassium exchange pump in skeletal muscle fibres

Results are presented which suggest that the contribution to the membrane potential in frog skeletal muscle evoked by ionic pump activity is made up of two components. One of these is directly related to the ‘electrogenic’ mode of pump action; the other, of similar magnitude, is an indirect effect due to potassium depletion in the lumen of the T-tubular system. The extent of this depletion has been estimated.
Phase III study of oral compared with intravenous topotecan as second-line therapy in small-cell lung cancer.

PURPOSE Single-agent intravenous (IV) topotecan is an effective treatment for small-cell lung cancer (SCLC) after failure of first-line chemotherapy. This open-label, randomized, phase III study compared oral and IV topotecan in patients with SCLC sensitive to initial chemotherapy. PATIENTS AND METHODS Patients with limited- or extensive-disease SCLC, documented complete or partial response to first-line therapy, Eastern Cooperative Oncology Group performance status < or = 2, and measurable recurrent disease (WHO criteria) with a treatment-free interval of > or = 90 days were assigned to treatment with either oral topotecan 2.3 mg/m2/d on days 1 through 5 or IV topotecan 1.5 mg/m2/d on days 1 through 5 every 21 days. Primary end point was response rate as confirmed by an external reviewer blinded to treatment. RESULTS A total of 309 patients were randomly assigned. In intent-to-treat analysis, response rates were 18.3% with oral topotecan (n = 153) and 21.9% with IV topotecan (n = 151), with a difference (oral -IV) of -3.6% (95% CI, -12.6% to 5.5%). Median survival time was 33.0 weeks for oral and 35.0 weeks for IV topotecan; 1- and 2-year survival rates were 32.6% and 12.4% for oral topotecan, respectively, and 29.2% and 7.1% for IV topotecan, respectively. Third-line chemotherapy was similar for both groups (33% for oral; 35% for IV). Incidence of grade 4 toxicity in patients who received oral and IV topotecan was as follows: neutropenia in 47% and 64%, thrombocytopenia in 29% and 18%, grade 3 or 4 anemia in 23% and 31%, and sepsis in 3% and 3%, respectively. The most frequent nonhematologic adverse events (all grades) included nausea (43% oral; 42% IV), alopecia (26% oral; 30% IV), fatigue (31% oral; 36% IV), and diarrhea (36% oral; 20% IV). CONCLUSION Oral topotecan demonstrates activity and tolerability similar to IV topotecan in chemotherapy-sensitive SCLC patients and offers patients a convenient alternative to IV therapy.
Community trait overdispersion due to trophic interactions: concerns for assembly process inference

The expected link between competitive exclusion and community trait overdispersion has been used to infer competition in local communities, and trait clustering has been interpreted as habitat filtering. Such community assembly process inference has received criticism for ignoring trophic interactions, as competition and trophic interactions might create similar trait patterns. While other theoretical studies have generally demonstrated the importance of predation for coexistence, ours provides the first quantitative demonstration of such effects on assembly process inference, using a trait-based ecological model to simulate the assembly of a competitive primary consumer community with and without the influence of trophic interactions. We quantified and contrasted trait dispersion/clustering of the competitive communities with the absence and presence of secondary consumers. Trophic interactions most often decreased trait clustering (i.e. increased dispersion) in the competitive communities due to evenly distributed invasions of secondary consumers and subsequent competitor extinctions over trait space. Furthermore, effects of trophic interactions were somewhat dependent on model parameters and clustering metric. These effects create considerable problems for process inference from trait distributions; one potential solution is to use more process-based and inclusive models in inference.
Characterization of the Interaction Between Recombinant Human lnterferon‐γ and Its Receptor on Human Polymorphonuclear Leukocytes

The interaction of human recombinant interferon‐γ (rlFN‐γ) with human polymorphonuclear cells (PMN) was investigated. Bolton‐Hunter radioiodinated rlFN‐γ bound to PMN in a specific and saturable manner. Eleven hundred binding sites were observed with a Ka of 0.56 x 1010 M‐1. Binding to PMN was rapid with a K1 of 9 x 105 M‐1 sec‐1 at 4°C. At 37°C binding was complete within 6 min. About 50% of bound ligand was internalized within 30 min at 37°C. The receptor demonstrated moderate lability at 37°C in culture. After 1 h at 37°C, PMN lost 80% of their 125l‐rlFN‐γ binding sites. This loss was reversed in part by the presence of interleukin‐1 in the culture, but not tumor necrosis factor. These studies provide a framework for further investigation into the signalling process of rlFN‐γ on PMN.
The Price per Prospective Consumer of Providing Therapist Training and Consultation in Seven Evidence-Based Treatments within a Large Public Behavioral Health System: An Example Cost-Analysis Metric

Objective Public-sector behavioral health systems seeking to implement evidence-based treatments (EBTs) may face challenges selecting EBTs given their limited resources. This study describes and illustrates one method to calculate cost related to training and consultation to assist system-level decisions about which EBTs to select. Methods Training, consultation, and indirect labor costs were calculated for seven commonly implemented EBTs. Using extant literature, we then estimated the diagnoses and populations for which each EBT was indicated. Diagnostic and demographic information from Medicaid claims data were obtained from a large behavioral health payer organization and used to estimate the number of covered people with whom the EBT could be used and to calculate implementation-associated costs per consumer. Results Findings suggest substantial cost to therapists and service systems related to EBT training and consultation. Training and consultation costs varied by EBT, from Dialectical Behavior Therapy at $238.07 to Cognitive Behavioral Therapy at $0.18 per potential consumer served. Total cost did not correspond with the number of prospective consumers served by an EBT. Conclusion A cost-metric that accounts for the prospective recipients of a given EBT within a given population may provide insight into how systems should prioritize training efforts. Future policy should consider the financial burden of EBT implementation in relation to the context of the population being served and begin a dialog in creating incentives for EBT use.
Instability of Local Deformations of an Elastic Rod: Numerical Evaluation of the Evans Function

We present a method for the numerical evaluation of the Evans function that does not require integration in an associated exterior algebra space. This technique is suitable for the detection of bifurcations and is particularly useful when the dimension of the linearized system and/or the dimension of the converging subspaces at infinity is large. We test this approach by investigating the stability of a two-parameter family of traveling pulse solutions to two coupled Klein–Gordon equations. The spectral stability of these pulses is completely understood analytically [S. Lafortune and J. Lega, SIAM J. Math. Anal. , 36 (2005), pp. 1726–1741], and we show that our numerical method is able to detect bifurcations of the pulse family with very good accuracy.
Mechanisms of alcoholic pancreatitis

Alcoholic pancreatitis is a major complication of alcohol abuse. The risk of developing pancreatitis increases with increasing doses of alcohol, suggesting that alcohol exerts dose‐related toxic effects on the pancreas. However, it is also clear that only a minority of alcoholics develop the disease, indicating that an additional trigger may be required to initiate clinically evident pancreatic injury. It is now well established that alcohol is metabolized by the pancreas via both oxidative and non‐oxidative metabolites. Alcohol and its metabolites produce changes in the acinar cells, which may promote premature intracellular digestive enzyme activation thereby predisposing the gland to autodigestive injury. Pancreatic stellate cells (PSCs) are activated directly by alcohol and its metabolites and also by cytokines and growth factors released during alcohol‐induced pancreatic necroinflammation. Activated PSCs are the key cells responsible for producing the fibrosis of alcoholic chronic pancreatitis. Efforts to identify clinically relevant factors that may explain the susceptibility of some alcoholics to pancreatitis have been underway for several years. An unequivocal, functionally characterized, association is yet to be identified in clinical studies, although in the experimental setting, endotoxin has been shown to trigger overt pancreatic injury and to promote disease progression in alcohol‐fed animals. Thus, while the molecular effects of alcohol on the pancreas have been increasingly clarified in recent years, identification of predisposing or triggering factors remains a challenge.
In-vitro Evaluation of Scindapsus Officinalis (ROXB.) Schott. Fruit for Antioxidant Potential

In the present study, coarse powder of Scindapsus officinalis (Roxb.) Schott. fruit was extracted successively using hexane, chloroform, ethyl acetate and 50% ethanol. The ethyl acetate and 50% ethanolic extracts were investigated for its antioxidant activity by using nitric oxide and DPPH radical scavenging methods. The IC value was also calculated. Ascorbic acid was used as standard. Both the 50% ethanolic and 50 ethyl acetate extract were found to exert concentration dependent free radical scavenging activity but former extract was more effective than the later on. The highest free radical scavenging activity by Scindapsus officinalis fruit extracts was observed at concentration of 1000 µg/ml.
INTRODUCTION TO THE SPECIAL ISSUE ON JOB QUALITi^: WHAT DOES IT MEAN AND HOW MICHT WE THINK ABOUT IT?

There is evidence of increasing inequality in some measures of job outcomes. the young and the highly educated have been insulated against downward movements in job quality. union members have fared better with respect to job security and hours of work. there is some tentative evidence that falls in trade union density are associated with diminishingjob quality.
Telebehavioral Health

Mental health disorders are common and are associated with high levels of distress, disability, morbidity, and mortality [1]. However, many people with these disorders do not have access to mental health services. It is often difficult to recruit and retain mental health providers in rural and underserved communities, and this lack of access can sometimes force patients to travel long distances in order to obtain mental health services or to forgo such services altogether. Primary care or other medical providers are often placed in the position of serving patients with severe mental health conditions, with little or no specialty support. These factors reduce the quality of mental health services available to patients in rural and underserved communities. A growing body of literature suggests that the use of live interactive videoconferencing to provide mental health care has the potential to mitigate the workforce shortage, especially in remote and underserved areas [2, 3]. With such an arrangement, a provider at a distant location evaluates and treats a patient at their local clinical site via live interactive videoconferencing. This practice has been referred to by various terms: telebehavioral health, telepsychiatry, telemedicine, e-behavioral health, telemental health, e-care, telehealth, and telecare. Telebehavioral health can also be used for consultations between providers, education of providers and patients, and the integration of science-based treatment practices into routine clinical care. Clinical Applications Telebehavioral health has diagnostic and therapeutic uses across the lifespan. Common applications include diagnostic assessment, prehospitalization assessment, posthospitalization follow-up care, medication management, psychotherapy, and consultation. Telebehavioral…
Comparative effects of extremely high power microwave pulses and a brief CW irradiation on pacemaker function in isolated frog heart slices.

The existence of specific bioeffects due to high peak power microwaves and their potential health hazards are among the most debated but least explored problems in microwave biology. The present study attempted to reveal such effects by comparing the bioeffects of short trains of extremely high power microwave pulses (EHPP, 1 micros width, 250-350 kW/g, 9.2 GHz) with those of relatively low power pulses (LPP, 0.5-10 s width, 3-30 W/g, 9.2 GHz). EHPP train duration and average power were made equal to those of an LPP; therefore both exposure modalities produced the same temperature rise. Bioeffects were studied in isolated, spontaneously beating slices of the frog heart. In most cases, a single EHPP train or LPP immediately decreased the inter-beat interval (IBI). The effect was proportional to microwave heating, fully reversible, and easily reproducible. The magnitude and time course of EHPP- and LPP-induced changes always were the same. No delayed or irreversible effects of irradiation were observed. The same effect could be repeated in a single preparation numerous times with no signs of adaptation, sensitization, lasting functional alteration, or damage. A qualitatively different effect, namely, a temporary arrest of preparation beats, could be observed when microwave heating exceeded physiologically tolerable limits. This effect also did not depend on whether the critical temperature rise was produced by LPP or EHPP exposure. Within the studied limits, we found no indications of EHPP-specific bioeffects. EHPP- and LPP-induced changes in the pacemaker rhythm of isolated frog heart preparation were identical and could be entirely attributed to microwave heating.
One-step synthesis of graphene/SnO2 nanocomposites and its application in electrochemical supercapacitors

A one-step method was developed to fabricate conductive graphene/SnO2 (GS) nanocomposites in acidic solution. Graphite oxides were reduced by SnCl2 to graphene sheets in the presence of HCl and urea. The reducing process was accompanied by generation of SnO2 nanoparticles. The structure and composition of GS nanocomposites were confirmed by means of transmission electron microscopy, x-ray photoelectron and Raman spectroscopy. Moreover, the ultracapacitor characteristics of GS nanocomposites were studied by cyclic voltammograms (CVs) and electrical impedance spectroscopy (EIS). The CVs of GS nanocomposites are nearly rectangular in shape and the specific capacitance degrades slightly as the voltage scan rate is increased. The EIS of GS nanocomposites presents a phase angle close to π/2 at low frequency, indicating a good capacitive behavior. In addition, the GS nanocomposites could be promisingly applied in many fields such as nanoelectronics, ultracapacitors, sensors, nanocomposites, batteries and gas storage.
QoE Assessment of Fairness between Players in Networked Virtual 3D Objects Identification Game Using Haptic, Olfactory, and Auditory Senses

In this paper, we carry out QoE (Quality of Experience) assessment to investigate influences of olfactory and auditory senses on fairness for a networked virtual 3D object identification game with haptics. In the game, two players try to identify objects which are placed in a shared 3D virtual space. In the assessment, we carry out the game in four cases. Smells and sounds are presented in the first case, only sounds are done in the second case, and only smells are done in the third case. In the last case, we present neither smell nor sound. As a result, we demonstrate that the fairness deteriorates more largely as the difference in conditions between two users becomes larger.