Miracle-dz/UniFAR-FTUs huggingface dataset:
Components of a Teacher Education Curriculum for Learner Strategies.

This paper focuses on how to incorporate learner strategy instruction as part of regular teacher training courses, both preservice and inservice. Panelists Andrew Cohen, Carol Hosenfeld, Anna Chamot, Rebecca Oxford, Joan Rubin, Rhoda Curtis, and Anita Wenden addresses questions from the audience on a variety of topics related to teacher education and learner strategies. The questions include: (1) how do you educate teacher trainers to perceive their needs to include teaching strategies; (2) what teaching philosophy best fits learning strategy instruction; (3) how do you decide what it is that teachers need to know about learner strategies; (4) how do we assess or evaluate whether teachers are effectively teaching learner strategies; (5) what are the characteristics of good stratc.gy instruction; (6) how do you get secondary content-area teachers to take the time to teach learning strategies; (7) what obstacles do teachers face in incorporating learner strategies into their language curricula; (8) what would be the best way to introduce the concept of learner strategies; (9) what teaching strategies are appropriate for learner strategy instruction; and (10) how much time should teacher training take. (Contains 26 references.) (MDM) **********************************************************i.AA********** * Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** Components of a Teacher Education Curriculum for Learner Strategies (4105) TESOL Colloquium 1994, 28th Annual Convention and Exposition in Baltimore, Maryland'
A note on distortions from estimating the regional impacts of exogenous changes in output

ABSTRACT This paper demonstrates both theoretically and empirically that when outputs instead of final demands are exogenously predetermined, the traditional Leontief final demand model overestimates economic impact, and even more so in a multiregional context. We assess this premise vis-à-vis the Leontief output model using the 2013 interregional input–output table of the Republic of Korea. We find that from a multiregional perspective the standard Leontief final demand model yields substantially biased output multipliers for Chungbuk Province.
The Course of Inattention and Hyperactivity/Impulsivity Symptoms After Foster Placement

BACKGROUND: It is largely unknown whether symptoms of inattention and hyperactivity/impulsivity of foster children decline over time after placement and what the role of the quality and stability of the foster placement is on the course of attention-deficit hyperactivity disorder (ADHD) symptom trajectories. Longitudinal studies of normative trajectories of symptom types in nonreferred children may assist in appropriately diagnosing ADHD and designing the clinical treatment for foster children. OBJECTIVE: We described average level and slope of inattention and hyperactivity/impulsivity symptoms over time and examined parental (biological and foster) warmth and hostility and placement stability (number of foster-home moves and discharge from care) as reported by 3 informants (biological parent, foster parent, and classroom teacher) after considering maltreatment risks (child age, gender, sibling ADHD, and comorbidity) and use of ADHD medication. METHODS: We studied 252 maltreated children in 95 families during 4 yearly waves, beginning shortly after placement; children were assessed whether they remained in or were discharged from foster care. RESULTS: Average level of inattention declined according to the biological parent, whereas hyperactivity/impulsivity symptoms declined according to both biological and foster parents. Higher inattention was associated with lower parental warmth (foster parent), higher parental hostility (biological, foster, and teacher), and discharge from care (biological parent). Higher hyperactivity was also associated with lower parental warmth (foster parent) and higher parental hostility (biological and foster parent), higher (average) number of foster-home moves, and discharge from care (biological report). Higher teacher-derived hyperactivity symptoms were associated with a history of child abuse (versus neglect); however, abused children showed a steeper decline of hyperactivity over time than those with neglect histories. Unexpected interactions were found for the impact over time of parental (foster) warmth and number of foster-home moves. CONCLUSION: Findings point to the clinical usefulness of attending to the parenting quality and placement stability as malleable factors affecting symptom reduction subsequent to placement.
Identification of a Postendocytic Sorting Sequence in CCR5

The chemokine receptor 5 (CCR5), a member of the G protein-coupled receptor family (GPCR), is used by human immunodeficiency virus type 1 (HIV-1) with a R5 tropism as an entry receptor in addition to CD4. It is a key target for an antiviral action aiming at inhibiting the HIV-1 entry process. Only few data are available today regarding the mechanism involved in the intracellular trafficking process of CCR5. Understanding how CCR5 cell surface expression is regulated is particularly important with regard to HIV-1 entry inhibition. We set out to investigate whether CCR5 molecular determinants were involved in the postendocytic recycling and degradative pathways. We constructed progressive deletion mutants of the C-terminal domain of CCR5 that we stably expressed in HEK293 cells. All of the deletion mutants were expressed at the cell surface and were functional HIV-1 receptors. The deletion mutants were internalized after stimulation, but they lost their ability to recycle to the plasma membrane. They were rerouted toward a lysosomal degradative pathway. We identified here a sequence of four amino acids, present at the extreme C terminus of CCR5, that is necessary for the recycling of the internalized receptor, independently of its phosphorylation. A detailed analysis of this sequence indicated that the four amino acids acted as a postsynaptic density 95/discs-large/zona occludens (PDZ) interacting sequence. These results show that the CCR5 cytoplasmic domain bears a sequence similar to the “recycling signals” previously identified in other GPCRs. Drugs able to disrupt the recycling pathway of CCR5 may constitute promising tools for therapeutic treatment.
Cholesterol efflux pathways and other potential mechanisms involved in the athero‐protective effect of high density lipoproteins

Plasma high density lipoprotein (HDL) levels bear a strong independent inverse relationship with atherosclerotic cardiovascular disease. Although HDL has anti‐oxidant, anti‐inflammatory, vasodilating and anti‐thrombotic properties, the central anti‐atherogenic activity of HDL is likely to be its ability to remove cholesterol and oxysterols from macrophage foam cells, smooth muscle cells and endothelial cells in the arterial wall. To some extent, the pleotropic athero‐protective properties of HDL may be related to its ability to promote sterol and oxysterol efflux from arterial wall cells, as well as to detoxify oxidized phospholipids. In cholesterol‐loaded macrophages, activation of liver X receptors (LXRs) leads to increased expression of adenosine triphosphate (ATP) binding cassetter transporter (ABCA1), ATP binding cassetter transporter gene (ABCG1) and apoE and promotes cholesterol efflux. ABCA1 stimulates cholesterol efflux to lipid‐poor apolipoproteins, whilst ABCG1 promotes efflux of cholesterol and oxysterols to HDL. Despite some recent setbacks in the clinical arena, there is still intense interest in therapeutically targeting HDL and macrophage cholesterol efflux pathways, via treatments with niacin, cholesterol ester transfer protein inhibitors, LXR activators and infusions of apoA‐1, phospholipids and peptides.
The Protein Interaction Network of the Human Transcription Machinery Reveals a Role for the Conserved GTPase RPAP4/GPN1 and Microtubule Assembly in Nuclear Import and Biogenesis of RNA Polymerase II*

RNA polymerase II (RNAPII), the 12-subunit enzyme that synthesizes all mRNAs and several non-coding RNAs in eukaryotes, plays a central role in cell function. Although multiple proteins are known to regulate the activity of RNAPII during transcription, little is known about the machinery that controls the fate of the enzyme before or after transcription. We used systematic protein affinity purification coupled to mass spectrometry (AP-MS) to characterize the high resolution network of protein interactions of RNAPII in the soluble fraction of human cell extracts. Our analysis revealed that many components of this network participate in RNAPII biogenesis. We show here that RNAPII-associated protein 4 (RPAP4/GPN1) shuttles between the nucleus and the cytoplasm and regulates nuclear import of POLR2A/RPB1 and POLR2B/RPB2, the two largest subunits of RNAPII. RPAP4/GPN1 is a member of a newly discovered GTPase family that contains a unique and highly conserved GPN loop motif that we show is essential, in conjunction with its GTP-binding motifs, for nuclear localization of POLR2A/RPB1 in a process that also requires microtubule assembly. A model for RNAPII biogenesis is presented.
Few Aspects Concerning the Marketing Particularities in Healthcare Services

Approaching healthcare services from a marketing point of view is a very complex and complicated issue. On one hand, the Health Ministry has the strategic role of writing the health policy of a country, but on the other hand, certain particular interests can appear in the case of pharmacies, hospitals, clinics or individual doctors’ offices etc., interests which might not always correspond to the central policies. Each one of these actors formulates its own marketing policy, creates and supplies specific products (medical investigations, treatments, cures etc.), establishes prices for these products, distributes them through marketing channels and communicates with stakeholders about these products and themselves. The aim of this paper is to present a few aspects of marketing approach in the system of healthcare services.
Supporting environmental surveillance by using wireless sensor networks

Wireless sensor networks have to be very flexible and self-configuring, providing an easy way to be deployed. This is a feature that is required due to a wide spectrum of possible applications and deployment scenarios in which they can be used. They can support different kinds of tools and applications in distinct areas, such as agriculture, military, health care, home or industry automation and others. An environmental surveillance system supported by a WSN is presented in this work. The main feature of this system is to locate and track inhabitant's moving behaviour. The system has been implemented using Iris Motes which were placed in different rooms in a building. In order to simplify the deployment and monitoring of the WSN, this project investigated and used an interface called MoteView, which represents a graphical user interface tool. The use of temperature sensor is investigated in order to track people and the results performed in this work required developing custom TinyOS components to implement data acquisition, data transmission and data reception.
Robust design of sparse relative sensing networks

This paper considers the robust design of sparse relative sensing networks subject to a given H∞-performance constraint. The topology design considers heterogenous agents over weighted graphs. We develop a robust counterpart to the uncertain optimization problem and formulate the sparsity constraint via a convex ℓ1-relaxation. We also demonstrate how this relaxation can be used to embed additional performance criteria, such as the maximization of the algebraic connectivity of the relative sensing network.
Power minimization in multi-user OFDMA-based cognitive radio systems with guaranteed throughput provision

Cognitive Radio (CR) is an innovative technology, which will capable future wireless networks to utilize the spectrum more efficiently. Orthogonal Frequency Division Multiplexing (OFDM) because of its unique features, is one of the best candidates for implementing CR. Due to services that new generations of networks are presenting, a guaranteed throughput for these networks becomes so important. In this paper, a resource allocation algorithm for the downlink of a multi-user OFDM-based CR system is presented. The presented algorithm provides a guaranteed throughput for CR users, with minimum power consumption while keeping the interference to each primary user (PU) below a certain threshold. The performance of the proposed algorithm is compared with Sum Throughput Maximization Algorithm and Uniform Resource Allocation Algorithm.
Technology And Security In The 21st Century A Demand Side Perspective

Thank you for reading technology and security in the 21st century a demand side perspective. As you may know, people have look hundreds times for their favorite novels like this technology and security in the 21st century a demand side perspective, but end up in infectious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they are facing with some infectious virus inside their computer.
A Descriptive Study of Dual Enrollment in Public High Schools Enrolling Grades 9-12 in New York State and Implications for Policy Changes

There is a need to increase college readiness among high school graduates to promote college success and degree attainment (Blume & Zumeta, 2013; McMahon, 2009; Reindl, 2007). Sixty percent of first semester college students are not college ready and prepared to succeed in college (National Center for Public Policy on Higher Education, 2010). Dual enrollment programs are a noted pathway to increase college readiness among high school students (Hoffman, 2003; Pretlow & Wathington, 2014). Forty-seven states have dual enrollment policies. New York has no statewide policy and dual enrollment programs vary among public high schools throughout the state. This descriptive study examined dual enrollment programs in public high schools in New York. The study sought to determine what, if any, differences exist in dual enrollment programs throughout the state. A quantitative, descriptive, cross-sectional research design was utilized. The findings from this research identified several differences among dual enrollment programs throughout the state. Differences included type and quantity of courses, tuition responsibility, and how parents and students receive program information, among others. The research identified challenges and successes of dual enrollment programs. The results of this study are important to New York policymakers seeking to standardize dual enrollment programs, ensure students access, increase college readiness and college enrollment, increase degree attainment, and prepare the workforce to compete globally in the years ahead. Document Type Dissertation Degree Name Doctor of Education (EdD) Department Executive Leadership First Supervisor Linda Hickmon Evans Subject Categories Education This dissertation is available at Fisher Digital Publications: https://fisherpub.sjfc. edu/education_etd/280 A Descriptive Study of Dual Enrollment in Public High Schools Enrolling Grades 9-12 in New York State and Implications for Policy Changes
Psychotropic practice patterns for youth: a 10-year perspective.

OBJECTIVE To examine changes in the full spectrum of psychotropic medication treatment for youths from 1987 to 1996. METHODS A population-based analysis of community treatment data on nearly 900,000 youths enrolled in 2 US health care systems included (1) computerized Medicaid data from 2 states (a midwestern state and a mid-Atlantic state) composed of outpatient prescription claims and enrollment records and (2) computerized prescription dispensing records from a group-model health maintenance organization. Ten 1-year cross-sectional data sets from 1987 through 1996 were analyzed. RESULTS Total psychotropic medication prevalence for youths increased 2- to 3-fold and included most classes of medication. The rapid growth since 1991 of alpha-agonists, neuroleptics, and "mood stabilizer" anticonvulsants was particularly notable. The 1996 prevalence of any psychotropic medication among youths younger than 20 years was remarkably similar (5.9%-6.3%) across all 3 sites, with stimulants and antidepressants consistently ranked first and second. Medicaid rates almost always exceeded health maintenance organization rates by large margins, particularly for alpha-agonists, neuroleptics, "mood stabilizer" anticonvulsants, and lithium. Youths in health maintenance organizations had rates similar to Medicaid-insured youths for antidepressants and hypnotics. Over the decade, there was a proportional increase in females receiving stimulants and in males receiving antidepressants, particularly for the 10- to 14-year-old group. The prevalence ratios of whites to African Americans narrowed substantially in 1 Medicaid site. CONCLUSIONS Youth psychotropic treatment utilization during the 1990s nearly reached adult utilization rates. Youth findings can be used to accurately assess the duration of treatment and unforeseen practice pattern changes, and to identify safety concerns.
Confirmatory platelet-activating factor receptor antagonist trial in patients with severe gram-negative bacterial sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. BN 52021 Sepsis Investigator Group.

OBJECTIVE To determine the efficacy and safety of using natural platelet-activating factor receptor antagonist (PAFra), BN 52021, to treat patients with severe Gram-negative bacterial sepsis. DESIGN A prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial. SETTING Fifty-nine academic medical center intensive care units in Europe. PATIENTS Six hundred nine patients with severe sepsis, suspected to be related to Gram-negative bacterial infection, who received PAFra or placebo. INTERVENTIONS Patients were randomized to receive either a dose of PAFra (120 mg iv) every 12 hrs over a 4-day period or placebo over a 4-day period. MEASUREMENTS AND MAIN RESULTS The patients were well matched at study entry for severity of illness and for risk factors known to influence the outcome of sepsis. Among all randomized patients, the 28-day, all-cause mortality rate was 49% (152/308) in the placebo group, and 47% (140/300) in the PAFra group (p=.50). When analyzed on the basis of the previously defined target population, the 28-day, all-cause mortality rate was 50% (115/232) in the placebo group and 44% (94/212) in the PAFra group, yielding a 12% reduction in mortality rate (p=.29). In patients with documented infection involving other organisms, there was no difference between treated and placebo groups. When the outcomes of organ dysfunctions were examined in the overall population and in the documented Gram-negative bacterial infection population, the number of patients who resolved hepatic dysfunction tended to be higher in the treated group than in the placebo group (p=.06). The number of adverse events reported were not different between the two groups. CONCLUSIONS A 4-day administration of the studied PAFra (BN 52021) failed to demonstrate a statistically significant reduction in the mortality rate of patients with severe sepsis suspected to be related to Gram-negative bacterial infection. If PAFra treatment has any therapeutic activity in severe Gram-negative bacterial sepsis, the incremental benefits are small and will be difficult to demonstrate in a patient population as defined by this clinical trial.
Anatomical information is needed in ultrasound imaging of muscle to avoid potentially substantial errors in measurement of muscle geometry

This study validates two‐dimensional (2D) ultrasound measurements of muscle geometry of the human medial gastrocnemius (GM) and investigates effects of probe orientation on errors in these measurements. Ultrasound scans of GM muscle belly were made both on human cadavers (n = 4) and on subjects in vivo (n = 5). For half of the cadavers, ultrasound scans obtained according to commonly applied criteria of probe orientation deviated 15° from the true fascicle plane. This resulted in errors of fascicle length and fascicle angle up to 14% and 23%, respectively. Fascicle‐like structures were detectable over a wide range of probe tilt and rotation angles, but they did not always represent true fascicles. Errors of measurement were either linear or quadratic functions of tilt angle. Similar results were found in vivo. Therefore, we conclude that similar errors are likely to occur for in vivo measurements. For all cadavers, at the distal end of GM, the true fascicle plane was shown to be perpendicular to the distal aponeurosis. Using transverse images of GM to detect the curvature of the deep aponeurosis at the distal end of the muscle belly is a simple strategy to help identify the fascicle plane. For subsequent longitudinal imaging, probe alignment within this plane will help minimize measurement errors of fascicle length, fascicle angle, and muscle thickness. Muscle Nerve, 2009
A simulation-based approach to forecasting the next great San Francisco earthquake

In 1906 the great San Francisco earthquake and fire destroyed much of the city. As we approach the 100-year anniversary of that event, a critical concern is the hazard posed by another such earthquake. In this article, we examine the assumptions presently used to compute the probability of occurrence of these earthquakes. We also present the results of a numerical simulation of interacting faults on the San Andreas system. Called Virtual California, this simulation can be used to compute the times, locations, and magnitudes of simulated earthquakes on the San Andreas fault in the vicinity of San Francisco. Of particular importance are results for the statistical distribution of recurrence times between great earthquakes, results that are difficult or impossible to obtain from a purely field-based approach.
Subintimal angioplasty of tibial vessel occlusions in the treatment of critical limb ischaemia: mid-term results.

OBJECTIVES to evaluate the feasibility and preliminary results at 1 year of subintimal angioplasty of tibial occlusions in critical limb ischaemia (CLI). MATERIAL from December 1997 to December 1999, we intended to treat 36 patients and 40 limbs by subintimal angioplasty of occlusions of tibial vessels. Thirty-one had gangrene or ulceration and nine had rest pain. Twenty-seven occlusions were more than 10 cm, 10 were 5 to 10 cm and three were less than 5 cm in length. Three patients had an occluded previous ipsilateral bypass graft. All patients were followed 3 monthly for a median of 10 months by means of clinical and duplex examination. RESULTS the technical success rate was 78% (31/40). Nine technical failures were treated by conventional surgery or angioplasty of another diseased tibial vessel. The clinical success rate was 68% (27/40). Four below-the-knee amputations were performed despite a patent recanalisation. Primary and secondary patency rates at 12 months were 56% (72% without technical failures). The 12-month limb salvage rate was 81% and survival rate was 78%. Three of five complications were treated by endovascular procedures. The length of occlusion (>10 cm) but not the location of distal re-entry, the type of vessel re-entry and the presence of diabetes are predictors of technical success and patency. CONCLUSIONS subintimal angioplasty can be used to treat tibial occlusions in patients with CLI. Technical failure does not preclude conventional surgery and complications may often be treated by endovascular procedures. However, the durability of angioplasty is as yet uncertain.