Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of Social Media on Academic Journals.

S ocial media is no longer just a place where friends and strangers meet and connect on an individual level. It is a place where goods and ideas are exchanged globally, personal triumphs and pitfalls are shared, and news is reported and consumed. Increasingly, life is conducted on social media. The Pew Research Center reports that upward of 90% of American adults (aged 18-65 years) use social media, a phenomenon that has been trending upward over the past decade and is fairly consistent across age, gender, race, and socioeconomic status. Social media includes platforms such as Twitter, Facebook, Instagram, Pinterest, and Snapchat, to name a few. Social media also includes specific industryfocused platforms such as LinkedIn and Slack and a myriad of other sites that serve to connect professionals and facilitate either project collaboration or job search, recruitment, and placement. Academics and researchers have social media platforms specifically for exchanging ideas and collaborating on research. These platforms include Academia.edu and Researchgate.net. Some estimates put researchers’ use of these platforms at 25%, though others have estimated a much higher usage rate. Academics also use more traditional social media (eg, Twitter, Facebook) to share, debate, or promote research projects and findings, a likely growing number, given the
Power-Saving Design of Radio Frequency Identification Sensor Networks in Bus Seatbelt Monitoring Systems

Seatbelt state monitoring is important in intercity buses for passenger safety. This paper discusses the issues and challenges in power-saving design of radio frequency identification (RFID) sensor networks in bus seatbelt monitoring. A new design approach is proposed in this work for low-power layout and parameter setting in RFID sensor nodes in hardware and software design. A one-to-many pairing registration method is suggested between the concentrator and the seat nodes. Unlike using extra computer software to write seat identification (ID) into an integrated circuit (IC) card, the node ID in this project can be stored into the concentrator directly, which can reduce intermediate operations and reduce development costs. The effectiveness of the proposed low-power design approach is verified by some experimental tests.
Obsidian as a Raw Material for Eco-Friendly Synthesis of Magnetic Zeolites

A sample of rhyolitic obsidian (OS) was used as raw material for zeolite synthesis by long (4 days) and fast (2 h)-aging hydrothermal processes. Zeolite synthesis was also performed by a fast (2 h) sonication method. The products were analysed by X-ray diffraction (XRD) and scanning electron microscopy (SEM) both immediately after and 3 years after their formation in order to determine the stability of synthetic materials according to the method used. The results confirm zeolitization of obsidian both by long-aging conventional hydrothermal heating and fast hydrothermal process. However, the data highlight the efficiency of direct ultrasound energy in achieving more stable zeolite crystals over time. These results carried out using a natural source, follow those already obtained using wastes and pure sources as raw materials thus providing a definitive validation of the different mechanisms controlling zeolite formation according to the process used. Moreover, the results confirm the effectiveness of ultrasonic energy in the formation of zeolites that are more stable over time. Due to the chemical composition of the obsidian precursor, all synthetic zeolites show good magnetic properties (i.e., saturation magnetization), in view to potential magnetic separation.
Role of homocysteine in the development and progression of Parkinson’s disease

Homocysteine is an essential intermediate product of biochemical reactions that is present in various tissues of the human body. Homocysteine may be associated with the development and progression of Parkinson’s disease. Plasma homocysteine levels in patients with Parkinson’s disease are elevated compared to those of healthy individuals. High homocysteine drives PD development and progression while aggregating the clinical symptoms of PD patients. The relationship between PD and homocysteine involves multiple pathways, including nerve cell apoptosis, oxidative stress, and DNA damage. This is crucial for explaining how high homocysteine drives the PD procession. Elevated homocysteine level during PD development and progression offers a new strategy for the diagnosis and treatment of this disease.
Reliability of center of pressure excursion as a measure of postural control in bipedal stance of individuals with intellectual disability: A pilot study

The high prevalence of postural instability in individuals with intellectual disability (ID) warrants the need for reliable and practical postural control assessments. Stabilometry is a postural control assessment that has been widely used for clinical populations. However, the scant systematic knowledge about the reliability of stabilometric protocols for adults with ID renders results questionable and limits its value for clinicians and researchers. The study’s purpose was to develop a stabilometric protocol for adults with and without ID based on optimal combinations of shortest necessary trial durations and the least number of trial repetitions that guarantee sufficient reliability. Participants performed six trials of bipedal standing in 2 vision (eyes open vs eyes closed) x 2 surface (solid vs compliant) conditions on a force platform. Several parameters were calculated from the first 10-, 20-, and 30-s interval of every center-of-pressure (COP) trial data. For different trial durations, we identified the number of trials that yielded acceptable relative (intraclass correlation coefficient ≥ 0.70) and absolute (standard error of measurement < 20%) reliability using the Spearman-Brown prophecy formula. To determine the optimal combination of trial duration and number of repetition for each COP parameter, we implemented a two-step process: 1) identify the largest number of repetition for each of the three trial durations and then 2) select the trial duration with the lowest number of repetition. For both ID- and non-ID groups, we observed a trend whereby shorter trial durations required more repetitions and vice versa. The phase plane and ellipse area were the most and least reliable center-of-pressure parameter, respectively. To achieve acceptable reliability, four 30-s trials of each experimental condition appeared to be optimal for testing participants with and without ID alike. The results of this research can inform stabilometric test protocols of future postural control studies of adults with ID.
Influence of the Chicken Major Histocompatibility Complex on the Pathogenesis of Bacterial Skeletal Disease, Chicken Infectious Anemia and Infectious Bronchitis

This study evaluated bacterial skeletal disease in conjunction with the major histocompatibility complex (MHC) in a genetically pure line of broiler breeder chickens. Chickens from six broiler breeder flocks were examined for skeletal lesions, bacterial pathogens and MHC genotype. During a ten-week period, eighty-eight, 9to 21-week-old lame and 34 normal, age-matched controls were selected. Tenosynovitis, arthritis, and femoral or tibiotarsal (or both) osteomyelitis occurred in 86 of 88 (97.7%) lame chickens. Ninety-five bacterial isolates were obtained from 83 of 88 (94.3%) lame birds and 4 of 34 (11.8%) controls. Staphylococcus spp. was isolated from 72.6% of the skeletal lesions, predominantly Staphylococcus aureus (38.9%). MHC B complex genotypes were determined by hemagglutination for 88 lame birds, 34 controls and 200 randomly selected birds from each of the six flocks (1200 total). Combined Chi-square analysis revealed that the homozygous MHC genotypes B A4/A4 (χ = 14.54, P = 0.0063) and B A12/A12 (χ = 42.77, P = 0.0001) were over represented in the sample of symptomatic birds compared to random samples from the same flocks. The homozygous A4 and A12 MHC genotypes influenced flock Chi-square values more than the corresponding heterozygotes. An MHC B complex influence on bacterial skeletal disease was apparent in this line of broiler breeders.
Aureolic Acid Group of Agents as Potential Antituberculosis Drugs

Mycobacterium tuberculosis is one of the most dangerous pathogens. Bacterial resistance to antituberculosis drugs grows each year, but searching for new drugs is a long process. Testing for available drugs to find active against mycobacteria may be a good alternative. In this work, antibiotics of the aureolic acid group were tested on a model organism Mycobacterium smegmatis. We presumed that antibiotics of this group may be potential G4 ligands. However, this was not confirmed in our analyses. We determined the antimicrobial activity of these drugs and revealed morphological changes in the cell structure upon treatment. Transcriptomic analysis documented increased expression of MSMEG_3743/soj and MSMEG_4228/ftsW, involved in cell division. Therefore, drugs may affect cell division, possibly disrupting the function of the Z-ring and the formation of a septum. Additionally, a decrease in the transcription level of several indispensable genes, such as nitrate reductase subunits (MSMEG_5137/narI and MSMEG_5139/narX) and MSMEG_3205/hisD was shown. We concluded that the mechanism of action of aureolic acid and its related compounds may be similar to that bedaquiline and disturb the NAD+/NADH balance in the cell. All of this allowed us to conclude that aureolic acid derivatives can be considered as potential antituberculosis drugs.
Reference state and benchmark concepts for better biodiversity conservation in contemporary ecosystems

Measuring the status and trends of biodiversity is critical for making informed decisions about the conservation, management or restoration of species, habitats and ecosystems. Defining the reference state against which status and change are measured is essential. Typically, reference states describe historical conditions, yet historical conditions are challenging to quantify, may be difficult to falsify, and may no longer be an attainable target in a contemporary ecosystem. We have constructed a conceptual framework to help inform thinking and discussion around the philosophical underpinnings of reference states and guide their application. We characterize currently recognized historical reference states and describe them as Pre‐Human, Indigenous Cultural, Pre‐Intensification and Hybrid‐Historical. We extend the conceptual framework to include contemporary reference states as an alternative theoretical perspective. The contemporary reference state framework is a major conceptual shift that focuses on current ecological patterns and identifies areas with higher biodiversity values relative to other locations within the same ecosystem, regardless of the disturbance history. We acknowledge that past processes play an essential role in driving contemporary patterns of diversity. The specific context for which we design the contemporary conceptual frame is underpinned by an overarching goal—to maximize biodiversity conservation and restoration outcomes in existing ecosystems. The contemporary reference state framework can account for the inherent differences in the diversity of biodiversity values (e.g. native species richness, habitat complexity) across spatial scales, communities and ecosystems. In contrast to historical reference states, contemporary references states are measurable and falsifiable. This ‘road map of reference states’ offers perspective needed to define and assess the status and trends in biodiversity and habitats. We demonstrate the contemporary reference state concept with an example from south‐eastern Australia. Our framework provides a tractable way for policy‐makers and practitioners to navigate biodiversity assessments to maximize conservation and restoration outcomes in contemporary ecosystems.
Growth Hormone & Hypopituitarism

Submit Manuscript | http://medcraveonline.com most important aspects among them. GH deficiency due to hypopituitarism may occur in adulthood or childhood. Childhoodonset disease is mostly idiopathic or genetic, whereas, in adults, the hypopituitarism is caused mainly by causes like a pituitary tumour, irradiation, inflammation, apoplexy, pituitary surgery etc. The most commonly associated clinical features are short stature or growth failure (in children) and increased lean muscle mass, increased visceral /central fat, lack of energy and exercise (in adults) etc. GH deficiency is also associated with insulin resistance and increased cardiovascular risk. In untreated patients, there is high morbidity, usually as a sequel to conditions like myocardial infarction, cerebrovascular disease, and malignancies. Both adultonset and child-onset types have different treatment protocols. In children, GH replacement is usually given in growth promoting dose and whereas in adults, it’s given at a ‘metabolic dose’ to cure symptoms.
Are Titania Photocatalysts and Titanium Implants Safe? Review on the Toxicity of Titanium Compounds

Titanium and its compounds are broadly used in both industrial and domestic products, including jet engines, missiles, prostheses, implants, pigments, cosmetics, food, and photocatalysts for environmental purification and solar energy conversion. Although titanium/titania-containing materials are usually safe for human, animals and environment, increasing concerns on their negative impacts have been postulated. Accordingly, this review covers current knowledge on the toxicity of titania and titanium, in which the behaviour, bioavailability, mechanisms of action, and environmental impacts have been discussed in detail, considering both light and dark conditions. Consequently, the following conclusions have been drawn: (i) titania photocatalysts rarely cause health and environmental problems; (ii) despite the lack of proof, the possible carcinogenicity of titania powders to humans is considered by some authorities; (iii) titanium alloys, commonly applied as implant materials, possess a relatively low health risk; (iv) titania microparticles are less toxic than nanoparticles, independent of the means of exposure; (v) excessive accumulation of titanium in the environment cannot be ignored; (vi) titanium/titania-containing products should be clearly marked with health warning labels, especially for pregnant women and young children; (vi) a key knowledge gap is the lack of comprehensive data about the environmental content and the influence of titania/titanium on biodiversity and the ecological functioning of terrestrial and aquatic ecosystems.
Microfluidic Production of Autofluorescent BSA Hydrogel Microspheres and Their Sequential Trapping for Fluorescence-Based On-Chip Permanganate Sensing

Microfabrication technologies have extensively advanced over the past decades, realizing a variety of well-designed compact devices for material synthesis, separation, analysis, monitoring, sensing, and so on. The performance of such devices has been undoubtedly improved, while it is still challenging to build up a platform by rationally combining multiple processes toward practical demands which become more diverse and complicated. Here, we present a simple and effective microfluidic system to produce and immobilize a well-defined functional material for on-chip permanganate (MnO4−) sensing. A droplet-based microfluidic approach that can continuously produce monodispersed droplets in a water-in-oil system is employed to prepare highly uniform microspheres (average size: 102 μm, coefficient of variation: 3.7%) composed of bovine serum albumin (BSA) hydrogel with autofluorescence properties in the presence of glutaraldehyde (GA). Each BSA hydrogel microsphere is subsequently immobilized in a microchannel with a hydrodynamic trapping structure to serve as an independent fluorescence unit. Various anions such as Cl−, NO3−, PO43−, Br−, BrO3−, ClO4−, SCN−, HCO3−, and MnO4− are individually flowed into the microchannel, resulting in significant fluorescence quenching only in the case of MnO4−. Linear correlation is confirmed at an MnO4− concentration from 20 to 80 μM, and a limit of detection is estimated to be 1.7 μM. Furthermore, we demonstrate the simultaneous immobilization of two kinds of different microspheres in parallel microchannels, pure BSA hydrogel microspheres and BSA hydrogel microspheres containing rhodamine B molecules, making it possible to acquire two fluorescence signals (green and yellow). The present microfluidics-based combined approach will be useful to record a fingerprint of complicated samples for sensing/identification purposes by flexibly designing the size and composition of the BSA hydrogel microspheres, immobilizing them in a desired manner and obtaining a specific pattern.
Study of in Vitro Cytotoxicity and in Vivo Anti- Tumour and Anti-Inflammatory Activities of Gmelina Arborea Roxb. Stem Bark

In this study the methanolic extract of the plant Gmelina arborea stem bark was evaluated for its anti inflammatory and anti tumour property. The anti inflammatory study was done in dextran and formalin induced inflammatory models, whereas the anti tumour activity was screened in solid and ascites tumour model in mice. The results clearly suggest that methanolic extract of Gmelina arborea possess significant anti inflammatory and anti cancer activity. The extract also showed in vitro cytotoxic effect on DLA and EAC cell lines. Further studies are required to confirm the exact mechanism underlining anti inflammatory and anti cancer property of the extract and to identify the chemical constituents responsible for it.
Global and local perspectives on cranial shape variation in Indonesian Homo erectus

Homo erectus is among the best-represented fossil hominin species, with a particularly rich record in Indonesia. Understanding variation within this sample and relative to other groups of H. erectus in China, Georgia, and Africa is crucial for answering questions about H. erectus migration, local adaptation, and evolutionary history. Neurocranial shape is analyzed within the Indonesian sample, including representatives from Sangiran, Ngandong, Sambungmacan, and Ngawi, as well as a comparative sample of H. erectus from outside of Java, using three-dimensional geometric morphometric techniques. This study includes several more recently described Indonesian fossils, including Sambungmacan 4 and Skull IX, producing a more complete view of Indonesian variation than seen in previous shape analyses. While Asian fossils can be distinguished from the African/Georgian ones, there is not a single cranial Bauplan that distinguishes all Indonesian fossils from those in other geographic areas. Nevertheless, late Indonesian H. erectus, from sites such as Ngandong, are quite distinct relative to all other H. erectus groups, including earlier fossils from the same region. It is possible that this pattern represents a loss of genetic diversity through time on the island of Java, coupled with genetic drift, although other interpretations are plausible. A temporal pattern of diachronic change was identified within Indonesia for the posterior neurocranium such that younger Sangiran fossils more closely approached the Ngandong/Sambungmacan/ Ngawi pattern, but there was not a linear trend of shape change from Sangiran to Sambungmacan to Ngandong, as has been suggested previously. The Sambungmacan 3 fossil, which often appears as a morphological outlier, fits the general pattern of late Indonesian vault shape, but has a more extreme expression of the shape trends for this group than other individuals.
Exploring the Link between Work Addiction Risk and Health-Related Outcomes Using Job-Demand-Control Model

Purpose of the study: Work addiction risk is a growing public health concern with potential deleterious health-related outcomes. Perception of work (job demands and job control) may play a major role in provoking the risk of work addiction in employees. We aimed to explore the link between work addiction risk and health-related outcomes using the framework of job-demand-control model. Methods: Data were collected from 187 out of 1580 (11.8%) French workers who agreed to participate in a cross-sectional study using the WittyFit software online platform. The self-administered questionnaires were the Job Content Questionnaire by Karasek, the Work Addiction Risk Test, the Hospital Anxiety and Depression scale and socio-demographics. Data Analysis: Statistical analyses were performed using the Stata software (version 13). Results: There were five times more workers with a high risk of work addiction among those with strong job demands than in those with low job demands (29.8% vs. 6.8%, p = 0.002). Addiction to work was not linked to job control (p = 0.77), nor with social support (p = 0.22). We demonstrated a high risk of work addiction in 2.6% of low-strain workers, in 15.0% of passive workers, in 28.9% of active workers, and in 33.3% of high-strain workers (p = 0.010). There were twice as many workers with a HAD-Depression score ≥11 compared with workers at low risk (41.5% vs. 17.7%, p = 0.009). Sleep quality was lower in workers with a high risk of work addiction compared with workers with a low risk of work addiction (44.0 ± 27.3 vs. 64.4 ± 26.8, p < 0.001). Workers with a high risk of work addiction exhibited greater stress at work (68.4 ± 23.2 vs. 47.5 ± 25.1) and lower well-being (69.7 ± 18.3 vs. 49.3 ± 23.0) compared with workers at low risk (p < 0.001). Conclusions: High job demands are strongly associated with the risk of work addiction. Work addiction risk is associated with greater depression and poor quality of sleep. Preventive strategies should benefit from identifying more vulnerable workers to work addiction risk.
Ecological and Evolutionary Consequences of Herbivory on Plant Communities

Understanding the consequences of species interactions is central to ecological and evolutionary research. My research focused on better understanding the evolutionary ecology of plantherbivore interactions by asking two broad questions: 1) How do herbivores shape the composition and diversity of plant populations and communities? And, 2) How does genetic variation and ongoing evolutionary dynamics in herbivores influence plant ecology? To test the first question, I utilized long-term herbivore manipulations in the grasslands of Silwood Park, England. I tested ecological and evolutionary consequences of rabbit (Oryctolagus cuniculus) grazing on plant populations by collecting seeds from rabbit exclosures ranging in age from 4 months to >20 years and growing them in common environments. I found that rabbit exclusion caused evolution of multiple plant defensive traits in three plant species and influenced the costs and benefits of a mutualistic interaction between a grass and its fungal endophyte. In another experiment at Silwood Park I investigated how multiple groups of herbivores (rabbits, insects, and mollusks) and nutrient additions shaped plant species richness and phylogenetic diversity. I found that nitrogen addition strongly reduced species richness while rabbit grazing increased plant phylogenetic diversity. To test the second question, I conducted field experiments where I