Miracle-dz/UniFAR-FTUs huggingface dataset:
The Extract Analysis and Antibacterial Survey of Different Parts of Guilan Native Clerodendrum bungei on Clinical Isolates

Medicinal uses of plants to treat of diseases has increased in recent years. Clerodendrum is a genus of plants belonging to Verbenaceae family. Clerodendrum bungei is native to the Guilan province, but its antibacterial effects has not been studied. For this reason the aim of the present study was to investigate the phytochemical analysis and antibacterial properties of the alcoholic extracts of Clerodendrum bungei. Clerodendrum bungei was collected from Sowme’ eh Sara city located in the northwest of the Guilan province, from May to August 2018 with equal amount. Extracts were prepared from different parts of Clerodendrum bungei using 70% ethanol by the maceration method and were analysed using GC/MS. Seven bacterial isolates from clinical samples were collected from patients referred to the social welfare polyclinic in Rasht. After confirmatory diagnostic tests for all specimens, an antibiogram test (disk diffusion method) was performed and the antimicrobial activities of the extracts were evaluated using disk diffusion and broth dilution methods on 7 isolates of E. coli, Enterobacter, Shigella, Klebsiella, Pseudomonas, Staphylococcus aureus, coagulase negative Staphylococcus. The results were showed that the alcoholic extract of the leaves before flowering was more effective on Pseudomonas than other bacteria. Also, the alcoholic extract of the leaves during flowering was effective on Staphylococcus aureus. The extract of the flower was effective on Escherichia coli only at a concentration of 250 mg/ml. The MIC values of the different alcoholic extracts of Clerodendrum bungei on all isolates were 8.06 to 500 mg/ml. The MBC values of the different extracts of Clerodendrum bungei on isolates were 500 mg/ml.The phytochemical compound, phytol was identified as the main component in the leaf extracts of C. bungei before (9.52%) and during (3.6%) flowering and therefore it seems to be the compound responsible for the antimicrobial properties of C. bungei leaves. The main effective components in the flowers, stems and roots of C. bungei were identified to be linalool (7.8%), aziridine (3.53%), thymol (21.84%), respectively. Linalol prevents dental cavity and has antiallergic, antiviral and antibacterial effects. Thymol has a very strong antimicrobial properties and can destroy outer membrane (OM) of gram-negative bacteria and remove the lipopolysaccharides and increase the permeability of the plasma membrane. Among the chemical compounds identified in the extracts, compounds with functional groups and acircular structure seems to have antibacterial properties. It is concluded from this study that Clerodendrum bungei possesses antibacterial properties.
ANTIOXIDANT SUPPLEMENTATION MINIMIZES THE NEGATIVE IMPACT OF DIETARY OXIDIZED OIL ON CHICKEN BROILER BREAST AND THIGH MEAT QUALITY

Studies have shown that animal nutrition can have a major impact on tissue gene expression, and, intuitively, may affect the quality of meat and meat products. This study investigated the influence of dietary antioxidants and quality of oil on the oxidative and physiochemical properties of chicken broiler breast and thigh meat stored in either an oxygenenriched (MAP: 80% O2/20% CO2) or an air-permeable polyvinylchloride (PVC) packaging system during retail display at 2-4 °C for up to 14 days. Broilers were fed 42 days either a diet with a low-oxidation (23.0 meq peroxide) or high-oxidation (121.3 meq peroxide) oil, supplemented with or without tocopherol/selenium-based antioxidants. Lipid and protein oxidation and purge loss were analyzed. In both packaging systems, lipid oxidation (TBARS) was inhibited by up to 65 and 57% in chicken breast and thigh, respectively with an antioxidantsupplemented diet, when compared with diets without antioxidants. In both breast and thigh samples, protein sulfhydryls and water-holding capacity (purge loss) were better protected by the antioxidant dietary treatment, regardless of oil quality. The results suggest that dietary antioxidants can minimize the negative impact of oxidized oil on broiler meat quality, and the protection may be linked to reduced lipid and protein oxidation.
Introducing Autonomous Vehicles: Adoption Patterns and Impacts on Social Welfare

Problem definition: Autonomous vehicles (AVs) are predicted to enter the consumer market in less than a decade. There is currently no consensus on whether their presence will have a positive impact on users and society. The skeptics of automation foresee increased congestion, whereas the advocates envision smoother traffic with shorter travel times. We study the automation controversy and advise policymakers on how and when to promote AVs. Academic/practical relevance: The AV technology is advancing rapidly and there is a need to study its impact on social welfare and the likelihood of its adoption by the public. Methodology: We use supply-demand theory to find the equilibrium number of trips for autonomous and regular households. We develop a simulation model of peer-to-peer AV sharing. We compare the socially optimal level of automation with the selfish adoption patterns where households independently choose their vehicle type. Results: We establish that the optimal social welfare is influenced by: (i) the network connectivity, that is, the ability of the infrastructure to serve AVs, (ii) the additional comfort provided by AVs that allows passengers to engage in other productive activities instead of driving, and (iii) the AV sharing patterns that reduce ownership costs, but create empty vehicle trips that increase congestion. Managerial implications: We investigate the impact of AVs in a case study of Toronto and show that partial automation maximizes social welfare. We show that the comfort of AVs may add traffic that compromises social welfare. Moreover, although traffic increases with automation, travel times may decrease because of significant improvements in traffic flow caused by AV connectivity in the network.
German Norms of the Harvard Group Scale of Hypnotic Susceptibility, Form A (HGSHS:A) and Proposal of a 5-Item Short-Version (HGSHS-5:G)

ABSTRACT The Harvard Group Scale of Hypnotic Susceptibility, Form A (HGSHS:A), is commonly used to test hypnotizability. There is still some controversy about what exactly hypnotizability is and whether and how it can be measured, especially by the HGSHS:A. Furthermore, a wider clinical use is limited, requiring a testing time of more than 1 hour. We analyzed the German HGSHS:A version for its factorial structure, item contribution, and item difficulty based on test data from six studies, including 1276 persons, to propose a shorter version of the HGSHS:A. We hereby present a 5-item version of the HGSHS:A (HGSHS-5:G), consisting of the challenge items, that was compared with an 11-item version (highly variable posthypnotic amnesia omitted). Age- and gender-specific norms was generated. The HGSHS-5: G showed high validity, reliability, and classification agreement. It reduces test time to 30 minutes thus facilitating wider use of hypnotizability testing.
DOSE RELATED ANXIOLYTIC EFFECTS OF DIAZEPAM: RELATION WITH SERUM ELECTROLYTES, PLASMA OSMOLALITY AND SYSTOLIC BLOOD PRESSURE (SBP) IN RATS

Diazepam is an anxiolytic and anticonvulsant drug that also induces hypnosis. Changes in serum electrolyte balance, plasma osmolality and systolic blood pressure (SBP) are often associated with stress-induced anxiety. Administration of diazepam has been shown to decrease stress-induced enhancement of hypothalamic pituitary adrenal cortical (HPA) axis. The present is designed to monitor the anxiolytic effects of different doses of diazepam (1mg/kg, 2.5mg/kg and 5mg/kg) and its association with changes of serum electrolyte balance, plasma osmolality and SBP in rats. Administration of diazepam at doses of 1mg/kg, 2.5mg/kg and 5mg/kg elicited anxiolytic effects monitored in light-dark transition test and increased serum concentration of electrolytes and plasma osmolality. Serum levels of magnesium as well as SBP decreased. The results are discussed in context of anxiolytic effects of diazepam to be mediated via a modulation of stressinduced increase in the activity of HPA-axis and electrolytes balance.
Elevated body temperature contributes to the increased heart rate response during eccentric compared to concentric cycling when matched for oxygen consumption

ABSTRACT A cardiovascular requirement to facilitate thermal homeostasis may partly contribute to the elevated heart rate during eccentric cycling. This study compared the body temperature response to a bout of eccentric (ECC) and concentric (CON) cycling to account for the difference in heart rate. Eight (N = 8) aerobically trained males (age 35 y [SD 8], peak oxygen consumption 3.82 L.min−1 [SD 0.79]) completed an ECC cycling trial (60% PPO) followed by an oxygen consumption/duration matched CON trial (30 , 35% RH) on a separate day. Trial termination was determined as an elevation in aural temperature, a surrogate of deep body temperature, by +0.5 during ECC. Mean skin (8-sites) and body temperature (weighting of 80:20 for auditory canal and mean skin temperature) were calculated. Matching the oxygen consumption between the trials increased external work during ECC cycling (CON: 71 [SD 14] ECC: 194 [SD 38] W, p < 0.05) and elevated aural temperature (+0.5 ) by 20 min 32 s [SD 9 min 19 s] in that trial. The peak rate of rise in aural temperature was significantly greater in ECC (CON: 0.012 [SD 0.007] ECC: 0.031 [SD 0.002] oC.s−1, p < 0.05). Aural, mean skin and body temperature were significantly higher during the ECC trial (p < 0.05) and this was accompanied by elevated mean heart rate (CON: 103 [SD 14] ECC: 118 [SD 12] b.min−1, p < 0.05) and thermal discomfort (p < 0.05). Moderate load eccentric cycling imposes an elevated thermal strain when compared to concentric cycling. This requirement for dissipating heat, in part, explains the elevated heart rate during eccentric cycling.
A Review of Chinese Literature on Ambidexterity Innovation and Its Future Prospects

On the basis of conceptual research on dual innovation by foreign scholars, through searching and reading the research literature on dual innovation published in domestic journals since 2020, it is found that domestic scholars have found that the status of resources, organizational environment, network structure, learning and knowledge From the perspective of technology, a lot of research has been done on the path mechanism, influencing factors and corporate performance of dual innovation. Therefore, by reviewing the research themes in recent years, firstly, it summarizes the current research status of dual innovation from the above aspects, secondly describes the current existing dual innovation research perspectives, and finally looks forward to future research. Keywords— Ambidexterity innovation; Path and mechanism; Influencing factor; Corporate performance.
: JANAPATI | 326 ANALISIS KESUKSESAN IMPLEMENTASI APLIKASI ONLINE SINGLE SUBMISSION MENGGUNAKAN METODE DELONE DAN MCLEAN

This research aims to analyze the successful implementation of the Online Single Submission (OSS) application using the Delone and Mclean method at the Investment Service and One Stop Integrated Service (DPMPTSP). This research is a quantitative research using a survey method. The population of this research is the users of the information system, amounting to 55 people. A total of 48 respondents were selected as a sample determined by the group random sampling technique. The results showed that system quality, information quality, service quality and individual impact had an influence on organizational impact of 95.9% and an effect on the level of user satisfaction by 64.55% which was in the high enough category. Based on these results, there is a successful implementation of the OSS application using the Delone and Mclean method at DPMPTSP Buleleng Regency. From these results, it is hoped that in the future the OSS application can be implemented in other government agencies in Buleleng Regency.
Minimum Wage Impact on RMG Sector of Bangladesh: Prospects, Opportunities and Challenges of New Payout Structure

Strike and labor unrest is very much common for the Readymade Garments (RMG) sector of Bangladesh. Most of them are basically for payment related issue like irregular wage payment practice of the garment factories owners and significant lag time of wage payment to the workers. With a view to maintaining stability in RMG sector, Ministry of Labor and Employment published new wage structure specially for the RMG sector in November 2018. Though new payout structure has been approved the effective implementation has become a great challenge for the governmental or regulatory authority as more than 50 percent increment in the lower graded workforce gross payout generates expectation gap of the owners of the RMG factories regarding the passion and value generating activities of the lower graded or minimum payout holder working force. High turnover in lower graded labor force and lack of working dedication generates reluctance of the owners to implement new payout structure of RMG sectors. However early stage patience and passion for working in RMG sector may gift a better career growth for the new workforce. Results have also justified the affiliation of a number of factors that may get influenced for the implementation of new minimum wage payout in the RMG sector.
BENCHMARKING A CHILD NUTRITION PROGRAM AGAINST CASH: EVIDENCE FROM RWANDA∗

We present the results of a study that benchmarks a multi-dimensional child nutrition intervention against the same donor program cost being disbursed directly to beneficiary households to spend as they see fit. Randomized variation in cash transfer amounts allows us to estimate impacts of cash transfers at expenditure levels equivalent to the in-kind program, as well as to estimate the return to increasing cash transfer values. Focusing on poor households with children or pregnant mothers, we find that neither the in-kind program nor a cost-equivalent transfer of $134 per household moves core child outcomes within a year. By contrast, a much larger cash transfer of more than $500 improves consumption and investment outcomes, as well as driving modest improvements in dietary diversity and child growth. We find little evidence of heterogeneity that would allow overall benefits to be improved by selectively targeting modalities, whether by pre-selected characteristics or machine learning. We find one-time cash transfers to generate as much benefit as a flow of transfers across 12 months, and little additional benefit from allowing households to choose their cash modality. Our methodology allows us to contrast a comparative cost effectiveness approach with one that looks at differential impacts across programs at a cost equivalent level.
The interobserver reliability of first metatarsal rotational component of axial sesamoid radiographs in hallux valgus

Objective: Hallux valgus is a progressive triplanar deformity of the forefoot with an important rotational component (RC) in the first metatarsal, which has been associated with recurrence. There is controversy about using weight-bearing vs. non-weight-bearing radiographs in RC measurement. This study aims to assess interobserver reliability for RC of the first metatarsal using a non-weight-bearing sesamoid view, as well as to correlate the hallux valgus angle, intermetatarsal angle, distal metatarsal articular angle (DMAA) and sesamoid position regarding RC. Methods: An observational, cross-sectional and descriptive study was conducted with 81 feet from 48 patients (66.6% female). RC was evaluated regarding the first metatarsal proximal shaft in non-weight-bearing axial metatarsal radiographs and weight-bearing anteroposterior radiographs. Measurements were taken independently by two foot and ankle subspecialists and an orthopedic resident, all of whom were blinded. Results: Statistically significant intraclass correlations (p = 0.02) were obtained for first metatarsal RC assessment among the three observers (95%CI 0.01–0.65; Cronbach’s α =0.41) in non-weight-bearing axial metatarsal views. Significant correlations (Spearman ρ) were also found for hallux valgus angle (p = 0.04) and DMAA (p = 0.01), and non-significant correlations were found for intermetatarsal angle and sesamoid position (p > 0.05). Conclusion: The significant correlations between hallux valgus angle and DMAA for RC suggest that RC is isolated from the first metatarsal bone structure. This practical assessment method may isolate the first metatarsal head RC regarding the proximal metatarsal in the metaphyseal region and could be useful in centers where weight-bearing CT scans are not available. Level of Evidence IV; Therapeutic Studies; Case Series.
Innovation and Organizational Resilience: A Study of Selected Small Scale Firms (SCFs) in Abuja Metropolis

This study investigated the influence of innovation on organizational resilience in the small and medium scale enterprises industry. The survey design was adopted. Data were obtained from 108 managers from a population of 385 management staff of the 7 selected small scale firms in Abuja, Nigeria. The instrument adopted for data collection was the questionnaire. A total of 78 questionnaires were retrieved and also analyzed. The Spearman’s Rank correlation coefficient tool was used to test the hypotheses. Findings revealed that product innovation is significantly related to adaptability and vulnerability. Based on these findings the study concluded that organizational innovation has significant influence on resilience. Product innovation promotes adaptability and makes small scale organizations less vulnerable. The study therefore recommends that small scale organizations should create an enabling environment which encourages employee creativity and innovative capacities which will play a key role in building organizational resilience. Small scale firms should also implement policies and processes which would allow for informed changes to structure, work processes and operations which in turn would be beneficial to the organization
Integrated proteomics and histochemical analysis of Araucaria angustifolia (Bertol.) Kuntze (Araucariaceae) in embryogenic suspension culture

t Cell suspension culture is a useful in vitro model-system for both scaling up and conserving the Brazilian conifer Araucaria angustifolia. In the present work, cell suspension of Araucaria was subjected to proteomics, biochemical and histochemical analyses. The results revealed new insights underlying the molecular mechanism of proembryogenic masses transition in cell suspension. Embryogenic cell cultures were cultivated in a basal liquid medium modified in a Steward apparatus (orbital agitator). Cell growth dynamics was evaluated using cell volume after sedimentation, fresh weight, mitotic index, conductivity, pH, and the number of proembryogenic masses (PEMs: I, II, III). Histochemical parameters, cell viability, and cell death analyses were performed to pinpoint growth rates. Proteomics analysis was performed using two-dimensional electrophoresis, and protein identification was carried out by MALDI-TOF-TOF tandem mass spectrometry. Cell growth dynamics showed a predominance of PEM III. Maximum slope of the exponential phase growth in fresh weight occurred at exponential phase after 15 days (optimal cultivation time), after which cell viability and pH decreased, thereby allowing the identification of stressrelated proteins. Several metabolism and growth proteins were abundant, such as: cytoskeletal, WOX1, cytokinin-related, and auxin-related proteins acting on cell wall modification, suspensor cell formation, and PEM I to PEM III transition.
A novel methylation signature predicts inferior outcome of patients with PDAC

Pancreatic ductal adenocarcinoma (PDAC) will become the second most common cause of death in North America and Europe over the next 10 years owing to the lack of early diagnosis, poor treatment, and poor prognosis. This study evaluated the methylation array data of 184 patients with PDAC in The Cancer Genome Atlas database to explore methylation biomarkers related to patient outcome. Using Univariable Cox regression analysis and Lasso regression analysis method in the training dataset, it was found that the four DNA methylation markers (CCNT1, ITGB3, SDS, and HMOX2) were significantly correlated with the overall survival of patients with PDAC. Kaplan–Meier analysis showed that these four DNA methylation markers could significantly distinguish high-risk and low-risk patients. Receiver operating characteristic analysis further confirmed that the four DNA methylation markers had high sensitivity and specificity, which could predict the prognosis of patients. Moreover, there was a difference in the genetic mutations between high-risk and low-risk patients distinguished by the four-DNA methylation model, which can provide information for clinical treatment. Finally, compared with known biomarkers, the model was more accurate in predicting the prognosis of PDAC. This four-DNA methylation model has potential as a new independent prognostic indicator, and could be used for the diagnosis, monitoring, and precision medicine of pancreatic cancer.
Uses and gratifications of Generation Z within social networks: A Uses and gratifications of Generation Z within social networks: A dialectical investigation into the Facebook domain dialectical investigation into the Facebook domain

To date, little research has considered how various types of gratifications operate within SNSs such as Facebook (LaRose et al. 2001; Quan-Haase and Young, 2010; Wang, 2015). To address this gap, we explore Generation Z’s motivational behaviour through the lens of Uses and Gratifications Theory. Additionally, we investigate the types of gratification obtained by Generation Z through Facebook. The research adopted an interpretivist philosophy and employed a qualitative approach. The data collection method used semi-structured interviews, in conjunction with qualitative digital diary research. Research participants were requested to record emotions, behaviours and opinions in their digital diaries over a consecutive seven-day period. Corbin and Strauss’ (1990) Grounded Theory classification, methodological memos and Rose’s (2016) visual analysis assisted in the data analysis process. Generation Z are motivated to utilise Facebook in an attempt to attain their primary gratifications. They envisage attaining a sense of digital empowerment through gratifying their primary motivational needs. This is achieved through leveraging the quality of content produced within Facebook, which subsequently prompts the attainment of their primary gratifications. It is pivotal marketing communications practitioners produce content that comprises elements of creativity, emotion, humour, authenticity, transparency, tailored messaging, or incorporating facets of storytelling. Consequently, Generation Z Facebook users are incentivised to interact with the produced content and subsequently attain primary gratifications. Additionally, Generation Z will develop a positive perception to both the brand and the Facebook platform itself.