Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative Experimental Studies of Few L-Type and T-Type Ca 2+ Channel Blockers Against In-Ovo and In-Vitro Models of Angiogenesis

Angiogenesis is the development of new blood vessels from pre-existing one. The ion-channels on endothelium plays vital role in cell proliferation and related angiogenesis. We aimed to investigate the effects of L-type (Verapamil and Diltiazem) and T-type (Ethosuximide) Calcium Channel Blockers (CCBs) on neovascularization. The effects on neovascularization were investigated by in-ovo (CAM, Chick Chorioallantoic membrane) and in-vitro (aortic ring assay) methods. Each test drug was tested for at least 3 doses and the anti-angiogenic effect was compared with Suramin as standard and normal control groups. Various vital parameters were recorded during the experiment like the number of blood capillaries, sprouts formation, angiogenic score etc. The L-type Ca 2+ channel blockers Verapamil at the dose of 50μM, 110 and 220 μM/disk has shown significant (p < 0.001) reduction in the number of branching points in CAM assay. For the further confirmation, angiogenic activity was evaluated in vitro by rat aortic ring assay method; the area of sprouts was reduced by the medium and high dose of verapamil. Diltiazem has demonstrated modest anti-angiogenic activity by both the models, whereas T-type calcium channel blocker ethosuximide has not shown any effect on the neovascularization. Among all the tested drugs verapamil has shown the promising anti-angiogenic property. Thus verapamil and diltiazem may have antiangiogenic activity defines novel beneficial effects in angiogenic mediated pathological conditions in addition to their main indications in cardiovascular complications.
Adaptive user interface support for ubiquitous computing environments

Application developers are increasingly facing the need to cover a wider variety of target devices. The diversity of devices supporting software applications is expanding from PC, to mobile, home entertainment systems, and even the automotive industry. Maintaining a viable balance between development costs and market coverage has turned out to be a challenging issue when developing applications for such a ubiquitous ecosystem. In this paper, we present the webinos approach as a means to enable adaptive user interfaces for web-based applications in ubiquitous computing environments. We propose a model-based user interface adaptation framework driven by a rich description of the target delivery context.
Performance and meat quality of Nordic Red and Aberdeen Angus bulls offered faba bean or field pea based whole crop legume-cereal silages

The objective of this study was to determine the effects of silage plant species (faba bean and field pea based whole crop legume-cereals vs. grass) on performance and meat quality of growing Aberdeen Angus (AA) and Nordic Red (NR) bulls. A 2×3 factorial design was used. The experiment comprised 30 AA and 30 NR bulls. Both breeds were randomly allotted to the three feeding treatments. The compositions (g kg-1 dry matter) of diets were: 1) grass silage (650) plus rolled barley (350), 2) faba bean-wheat silage (650) plus rolled barley (350) and 3) pea-wheat silage (650) plus rolled barley (350). The experimental diets were offered as total mixed rations ad libitum. The AA bulls grew faster, had better feed conversion rates and superior dressing proportion and carcass conformation compared to the NR bulls. Replacing grass silage by whole crop legume-cereal silages in the diet did not have remarkable effects on animal performance, carcass characteristics or meat quality.
Molekulární genetika kolorektálního karcinomu

Souhrn Východiska: Kolorektální karcinom (colorectal cancer – CRC) je nádorové onemocnění tlustého střeva s každoročně dia gnostikovanými téměř 1,3 miliony nových pa cientů celosvětově. Mortalita na toto závažné nádorové onemocnění dosahuje již 8,5 %. Jedná se o 2. nečastější nádorové onemocnění u žen (1. nádor prsu) a 3. u mužů (1. nádor plic, 2. nádor prostaty). Tímto CRC patří vedle nádorů prsu, prostaty a plic k nejčastějším nádorovým onemocnění u mužů a žen na světě. V České republice je stále více než 50 % pa cientů s CRC dia gnostikováno v pokročilém stadiu (stadium III a IV). Z molekulárně genetického pohledu je CRC velice heterogenní onemocnění, na kterém se podílí mnoho faktorů. CRC má formu jak hereditární, kde dominují mutace v genech APC (FAP, aFAP), MMR (HNPCC) atd. , jejíž výskyt se pohybuje okolo 5– 10 %, tak formu sporadickou s výskytem 90– 95 %, kde dochází k postupné akumulaci mutací v široké škále genů. Znalost genetické podstaty (APC, KRAS, MMR, mikroRNA, CIMP atd.) jak hereditární, tak sporadické formy CRC je nezbytná nejen pro zahájení léčby, ale také pro odhadnutí celkového rizika, prognózy a následného follow-up pa cienta. Závěr: Tento článek shrnuje dosavadní molekulárně genetické aspekty patogeneze CRC.
Assessment of Genetic Polymorphism in Sugarcane Somaclones by Using Random Amplified Polymorphic DNA

Although many countries are producers, only six of them account for 65% of the world’s entire sugarcane production. Among these Brazil is the largest one (Viera 2002). It is very urgent to increase cane productivity without further area expansion to meet the future need of sugar and gur. The chemical composition of a matured, sound and normal sugarcane stalk of the species Saccharum officinarum are water 74.96%, sugar 13.40%, fibre 10.04%, ash 0.64%, N2 bodies 0.58%, fat and wax 0.38%. Sugarcane is propagated vegetatively for commercial planting by stem cuttings.
THE PENNSYLVANIA STATE UNIVERSITY SCHREYER HONORS COLLEGE DEPARTMENT OF ELECTRICAL ENGINEERING ANALYSIS OF DATA COLLECTION PROCESSES IN SPOTLIGHT-MODE SYNTHETIC APERTURE RADAR AND MAGNETIC RESONANCE IMAGING DANIEL NADER MIKHAIL SPRING 2016 A thesis submitted in partial fulfillment of the requirement

Synthetic Aperture Radar (SAR) is a radar imaging technique that is used to collect data about targets. These targets are typically landscapes, buildings and other planets. Since SAR can operate in any weather condition and during any time of day, it is a useful tool for military and scientific purposes. To collect the data, a radar is placed on one side of an aircraft while the aircraft hovers over the desired target. Spotlight-mode SAR, an operation mode of SAR, is capable of producing high-resolution images of targets as this method focuses only at one area of the target at a time. Magnetic Resonance Imaging (MRI), on the other hand, is a popular medical imaging technique. MRI acquires data to produce images of a body’s organs, tissues and skeletal system. The interactions between applied magnetic fields and nuclear spins are used to reconstruct images of a body’s internal organs and tissues. This thesis project focuses on the analysis of the data acquisition processes that take place in spotlight-mode SAR and MRI.
Effects of Wine Selection Attributes on Satisfaction and Repurchase Intention -Focused on the Moderating Effect of Wine Involvement-

In this study, a survey was carried out on wine consumers over age 20 experienced in wine purchase and drinking from December 1 through December 31, 2011 with the object of figuring out the effects of wine selection attributes on satisfaction and repurchase intention, and making an empirical analysis of the difference depending on involvement in wine. The findings of this study are summarized as follows. The effect of wine selection attributes on satisfaction showed that price, label and wine characteristic had a significant positive effect on satisfaction. The effect of wine selection attributes on repurchase intention showed that locality, price, and wine characteristic had a significant positive effect on repurchase intention. For wine attributes affecting satisfaction, the wine involvement moderated the relationship between locality, price, and satisfaction of wine attributes. And for wine attributes affecting repurchase intention, the wine involvement moderated the relationship between label and repurchase intention of wine attributes. In other words, local characteristics and reasonable prices of the cultivation areas for wine, and indigenous characteristics of wine in quality itself supported the existing preceded findings. And these findings showed the characteristics in that the wine involvement moderates satisfaction and repurchase intention.
FIDELIO TISCHNACHBAR – Ein Lehr- und Lernkonzept mit gesellschaftlicher Verantwortung

Zusammenfassung Ist es unsere gesellschaftliche Verantwortung, in Zeiten des demographischen Wandels die Fehl- und Mangelernahrung in der alternden Gesellschaft zum Thema der Ernahrungsbildung zu machen? In diesem Beitrag soll das Potential eines generationenubergreifenden Lehr- und Lernkonzeptes in Zeiten von Moden, Mythen, Moral, Medien, Macht… aus mehreren Perspektiven beleuchtet und erste Zwischenergebnisse prasentiert werden. Schlusselworter: Prakonzepte, Service Learning, Kompetenzentwicklung, Motivation ----- Bibliographie: Obermoser, Susanne: FIDELIO TISCHNACHBAR – Ein Lehr- und Lernkonzept mit gesellschaftlicher Verantwortung, HiBiFo, 2-2018, S. 46-61. https://doi.org/10.3224/hibifo.v7i2. 04
The Future of Influenza Vaccines: Developing Tools to Match Glycosylation Patterns Relevant for Protection

Influenza is a viral disease that is easily transmissible, and it is found around the world and can affect anyone regardless of their age group. There are 3 types of influenza viruses: A, B and C. Influenza viruses A and B are usually responsible for causing outbreaks of influenza from limited to major epidemics or even pandemics. The main preventive measure against this virus is annual vaccination, and the World Health Organization annually publishes recommendations for the production of influenza vaccines, but the protection observed so far has not been optimal. It has been proven that using egg as a substrate for vaccine production causes changes in the structure of proteins on the surface of influenza virus, and these changes could be involved in the low effectiveness of vaccines against influenza. Here we comment about platforms currently used to produce viruses for inclusion into influenza vaccines, and suggest alternatives to improve glycosylation patterns to resemble more closely those found in viruses infecting human beings, aiming to improve the effectiveness of protection conferred by these new vaccines.
Adolescent substance use in two European countries : Relationships with psychosocial adjustment , peers , and activities 1

Adolescents may use various substances to improve psychological wellbeing or to face personal discomfort. However, they may also use drugs because they fall in with a certain peer group, or have a boyfriend or girlfriend who draws them into risky or illegal activities. All of these motivations for substance use among adolescents may be well founded according to literature on adolescent development. The present crossnational study explores the relationships between adolescent psychological adjustment, peers, activities, and substance use. The Italian and Dutch versions of the Me and My Health questionnaire were administered to 970 Italian and Dutch adolescents (both genders, mean age 16 years old). In both countries, substance use was more strongly related to peer relationships and activities than to psychological adjustment. However, the country has a moderating role with respect to some of the aspects considered. The findings support that the most effective preventive interventions are those which involve the peer group and are adapted to the context. 1 This study was partially funded by a Marie Curie Fellowship within the European Community programme TMR, Training and Mobility of Researches, 6th call for proposals, contract No: ERBFMBIC972738 (Ciairano, 2004) and by Foundation CRT (Fondazione Cassa di Risparmio di Torino), Torino, Italy. 2 Correspondence: Department of Psychology. University of Torino. Via Verdi 10, 10124 Torino (Italy). EMail: ciairano@psych.unito. it 120 CIAIRANO et al. Adolescents, substances, psychological adjustment, peers, activities Int J Clin Health Psychol, Vol. 8, No 1
A Delicate Balancing Act: Negotiating with Gatekeepers for Ethical Research When Researching Minority Communities

Research and processes of knowledge production are often based on racialised and imperialistic frameworks that have led to either the exclusion or the pathologisation of minority groups. Researchers address issues of exclusion by adopting recruitment strategies that involve negotiating with gatekeepers to ensure the inclusion of minority or marginalised groups. This often involves in-depth scrutiny of gatekeepers and requires the researchers to negotiate deals and to make personal disclosures. However, there remains relatively little discussion on the pragmatic ethical issues facing researchers in the field as a result of these interactions. This article suggests that interactions with gatekeepers present ethical issues that can be effectively addressed and managed by researchers through the exercise of phronesis. Phronesis allows researchers to make critical ethical decisions based on the specific characteristics of the research sites and subjects, not least of which are those issues that emerge as a consequence of researcher positionality. Such decisions are not necessarily identified or accommodated through bureaucratic processes which govern research ethics. We advance the notion of research ethics as an ongoing process that requires researcher skills and engagement, rather than a one-off bureaucratic exercise.
Heavy metal and metalloid concentration dynamics in mine and surface waters in the vicinity of Chiprovtsi and Martinovo mines, Northwestern Bulgaria

Chiprovtsi silver-lead and Martinovo iron mines represent the biggest mining area in Northwestern Bulgaria, which was operated till 1999. Their long-lived operation leads to proved pollution of the environment in the vicinity of the mines, especially water and soil. Seasonal monitoring of heavy metal (Cu, Zn, Cd and Pb) and metalloid (As and Sb) concentrations in mine, surface (river) and drinking waters was carried out during May and August 2006 to determine the level of contamination of the Chiprovska Ogosta river basin resulting from the long-lived mining activity and whether these abandoned mines continue to be potential source for water pollution. This study proves significant As concentrations in mine (up to 170 μg/l) and surface waters (between 50 and 621 μg/l). The presence of other heavy metals, such as Cu, Cd, Zn and Pb, and metalloid — Sb is also recorded. Among them, Pb was found in considerable concentrations - up to 1456 pg/l during May 2006 sampling exhibiting great concentration variability between dry and wet sampling seasons. Sb is also determined in mine waters (up to 25 pg/l), but not exists in surface and drinking waters. Drinking waters are proved to be free of heavy metals and metalloids.
Current-induced breakdown of carbon nanofibers

We present a study of high-field transport in carbon nanofibers (CNFs) and breakdown phenomena due to current stress. In situ measurements with scanning transmission electron microscopy reveal that the failure mode of CNFs is strongly related to the morphology of graphite layers comprising CNFs. Comparison with carbon nanotube (CNT) breakdown is made, demonstrating that the current capacity of CNFs is described by a similar model as that of CNTs with a modification of the current capacity of each graphitic layer. The maximum current density is correlated with resistivity, leading to the conclusion that lower resistivity results in higher current capacity in CNFs.
Numerical Analysis of Design Parameters With Strong Influence on the Aerodynamic Efficiency of a Small-Scale Self-Pitch VAWT

In the paper, four key design parameters with a strong influence on the performance of a small-scale high solidity variable pitch VAWT (Vertical Axis Wind Turbine), operating at low tip-speed-ratio (TSR) are addressed. To this aim a numerical approach, based on a finite-volume discretization of two-dimensional Unsteady RANS equations on a multiple sliding mesh, is proposed and validated against experimental data. The self-pitch VAWT design is based on a straight blade Darrieus wind turbine with blades that are allowed to pitch around a feathering axis, which is also parallel to the axis of rotation. The pitch angle amplitude and periodic variation are dynamically controlled by a four-bar-linkage system. We only consider the efficiency at low and intermediate TSR, therefore the pitch amplitude is chosen to be a sinusoidal function with a considerable amplitude. The results of this parametric analysis will contribute to define the guidelines for building a full size prototype of a small scale turbine of increased efficiency.
Extracting Envelopes of Rossby Wave Packets

Abstract Packets of Rossby waves play an important role in the transfer of kinetic energy in the extratropics. The ability to locate, track, and detect changes in the envelope of these wave packets is vital to detecting baroclinic downstream development, tracking the impact of the analysis errors in numerical weather forecasts, and analyzing the forecast effects of targeted weather observations. In this note, it is argued that a well-known technique of digital signal processing, which is based on the Hilbert transform, should be used for extracting the envelope of atmospheric wave packets. This technique is robust, simple, and computationally inexpensive. The superiority of the proposed algorithm over the complex demodulation technique (the only technique previously used for this purpose in atmospheric studies) is demonstrated by examples. The skill of the proposed algorithm is also demonstrated by tracking wave packets in operational weather analyses from the National Centers for Environmental Prediction.
A STRUCTURED REVIEW OF COMPLEXITY IN ENGINEERING-PROJECTS State-of-research and solution concepts for the plant manufacturing business

The term ‘complexity’ has been present in academic discussion and industrial practice for many years. However, interpretations about its scope and content differ. While research focused on the product business, a common understanding and classification of complexity in the plant manufacturing industry are missing yet. Based on an extensive literature review and various analyses, this contribution aims to describe complexity from the perspective of plant manufacturing business. We found out that the differentiation of the dimensions multiplicity, variance, changeability and ambiguity, as well as elements and interactions seems to be an appropriate and suitable approach to structure complexity in an engineering context. Further this contribution identifies causes and illustrates consequences of complexity for a plant manufacturing company aiming for a better understanding of complexity in the plant manufacturing business.
Theoretical Analysis of Non-ablative Laser Texturing of Silicon Surface with a Continuous Wave Fiber Laser

Si is highly transparent to infrared fiber laser (λ=1090 nm) and the laser is not regarded as a suitable tool for ablation based silicon surface texturing. However, we have shown non-ablative texturing of Si surface is possible provided that suitable laser power and dwell time are chosen to produce peak surface temperature above the Si effective oxidation point of 1250 K and below the Si melting point of 1690 K. The phenomenon is explained through theoretical thermal analysis. The Kirchhoff transform is used to include the temperature dependent thermal conductivity. It is shown that with carefully adjusting laser parameters localized oxidation occurs and results in the formation of regularly patterned micro-bumps.
Rotational and translational effects in collisions of electronically excited diatomic hydrides

Collisional quenching and vibrational energy transfer proceed competitively with rotational energy transfer for several excited states of the diatomic radicals OH, NH, and CH. This occurs for a wide variety of molecular collision partners. This phenomenon permits the examination of the influence of rotational motion on the collision dynamics of these theoretically tractable species. Measurements can also be made as a function of temperature, i.e., collision velocity. In OH(A{sup 2}{Sigma}{sup +}), both vibrational transfer and quenching are found to decrease with an increase in rotational level, while quenching decreases with increasing temperature. This behavior indicates that for OH anisotropic attractive forces govern the entrance channel dynamics for these collisions. The quenching of NH(A{sup 3}II{sub i}) by many (although not all) collision partners also decreases with increasing rotational and translational energy, and NH(c{sup 1}II) behaves much like OH(A{sup 2}{Sigma}{sup +}). However, the quenching of CH(A{sup 2}{Delta}) appears to decrease with increasing rotation but increases with increasing temperature, suggesting in this case anisotropic forces involving a barrier or repulsive wall. Such similarities and differences should furnish useful comparisons with both simple and detailed theoretical pictures of the appropriate collision dynamics.
DALEC – energy calculation for day- and artificial lighting systems and their impact on energy demand of heating and cooling systems considering control strategies in different clime zones

DALEC is a new free web tool (www.dalec.net). Based on climate files DALEC allows energy calculation for artificial and daylight systems and their impact on heat and cooling loads in real-time. In this paper case studies are presented which demonstrate the impact of different control strategies for artificial and daylight systems in varying geographic climate zones on energy demand for lighting, heating and cooling.
Evaluating the Readiness of Cyber Resilient Bangladesh

Digitization is a fundamental driver of development and economic growth of the world in both urbanized and emerging markets. Vision “Digital Bangladesh by 2021” marks the countries journey towards becoming a developed nation and embracing the knowledge-based economy as means of achieving it. However the dependency on digitization increases vulnerabilities and risks including cybercrimes such as hacking, intrusion, fraud, harassment and more. Bangladesh government is aware of these threats and has initiated various measures to prevent them. In this paper we discuss the mechanism Bangladesh government has taken to make Bangladesh cyber resilient and the present condition of that initiative. This paper also presents a statistical analysis of various attacks and their results on the websites of Bangladesh.
Decorating and Filling of Multi-Walled Carbon Nanotubes with TiO2 Nanoparticles via Wet Chemical Method

Multi-walled carbon nanotubes (MWCNTs) have been successfully modified with TiO2 nanoparticles via wet chemical method. For this purpose tetra chloride titanium (TiCl4) was used as titanium source. MWCNTs were exposed at different amount of TiCl4 (0.25 and 0.1 ml) and different soaking times. The modified MWCNTs have been characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). TEM results showed that the MWCNTs were fully decorated with TiO2 at short term immersion. Increasing soaking time caused to fill the MWCNTs with TiO2 nanoparticles. The results showed that the amount of precursor had a significant role on quantity of decoration. The decoration of outer surface of MWCNTs with TiO2 was more noticeable at large amount of TiCl4. XRD results revealed that the crystalline structure of TiO2 on the surface and inner of MWCNTs was rutile. The average size of TiO2 nanoparticles which modified MWCNTs were 20 nm.