Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification of pericentriolar matrix protein 1 (PCM1) as a novel scaffold for Protein Kinase A (PKA) and NIMA-related kinase 10 (NEK10)

The pericentriolar material 1 (PCM1) assembles a molecular platform around the pericentriolar matrix and centrosome that is essential for cell division and microtubule dynamics, and plays a critical role in different aspects of mitosis and ciliogenesis. Here, we report an additonal layer of complexity and found that PCM1 nucleates a signaling complex at the pericentriolar matrix, which includes PKA and NEK10. By co-clustering two distinct signaling enzymes, PCM1 controls critical aspects of mammalian ciliogenesis. Within the PCM1 complex, PKA regulates NEK10 localization and stability, efficiently coupling cAMP signaling to the ubiquitin-proteasome system (UPS). In this context, PCM1 acts as relay that senses, transmits and integrates cAMP and mitogenic signals generated at cell membrane, regulating biological events at the pericentriolar matrix area and primary cilium. The molecular characterization of relevant protein complexes at specific sub-cellular compartments and understanding the role of scaffold platform in critical aspects of cell biology will likely contribute to the design of novel therapeutic approaches for human diseases.
Design of Flip-Flops for High Performance VLSI Applications Using Different CMOS Technology’s

In this paper low power, high-speed design of SET, DET, TSPC and C2CMOS Flip-Flop are designed and analyzed. As these flip-flops have a small area and low power consumption they can be used in various applications like digital VLSI clocking system, buffers, registers, microprocessors etc. The Flip-Flops are analyzed at 90nm technologies. The above designed Flip-Flops and Latches are compared in terms of its transistor count, power dissipation and propagation delay using DSCH and Micro wind tools. This project proposes low power high-speed design of flip-flops in which True Single-Phase Clocking (TSPC) and C2CMOS flip-flop compared with existing flip-flop topologies in term of its transistor count, power dissipation, propagation delay, parasitic values with the simulation results in micro wind.
Future Directions for Wave Data Collection in New South Wales

The NSW Waverider buoy network was developed in response to a series of destructive storms in 1974. The resulting wave database now has four stations with over 25 years of records and one site at Sydney with over 12 years of directional data. A summary of the data, including information from three directional buoys, is included in the paper for reference by coastal designers and managers. Ultimately, the information of most interest for coastal management in NSW relates to the inshore wave conditions. At present inshore wave data are mostly inferred by numerical transfer rather than through direct measurement. Given constraints on program funding, one future option may be to reduce the effort on deep water wave data collection while increasing the collection of selected inshore data. Such a change would need confidence in the adequacy of a reduced number of offshore stations to describe significant events on a statewide basis. In this paper a preliminary assessment of the accuracy of interpolating the wave conditions at one buoy location using the data from adjacent buoys is presented.
Classification Consumer Credit for Missing Value Dataset

The objective of the study is to find the best method to construct a model that could predict the future failure as a function of variables obtained from the customer profile. Decision Tree and Logistic Regression are classification algorithm. One of Decision Tree algorithm is Classification and Regression Tree (CART). It can used to analyze numeric and categorical data. Logistic Regression is more accurate than Decision Tree. In fact, there is some missing value in datasets. Amelia II is the best method to estimate missing value for numeric and categorical data. This study combines Amelia II to estimate missing value, Decision Tree to screening and re-categorization variable and Logistic Regression to classifying debtor into ‘good’ and ‘bad’ risk classes. We found that the accuracy of this combined method constant until 40% missing value. The Correct Classification Rate (CCR) value for 10% - 40% same as the CCR value for dataset without missing value. Otherwise, the accuracy decreased for missing value above 40%. This method is effective if missing value of the dataset below 40%. We recommend the bank to apply this method for classify risk of debtor if the missing value is below 40%.
SVS-JOIN: Efficient Spatial Visual Similarity Join over Multimedia Data

In the big data era, massive amount of multimedia data with geo-tags has been generated and collected by mobile smart devices equipped with mobile communications module and position sensor module. This trend has put forward higher request on large-scale of geo-multimedia data retrieval. Spatial similarity join is one of the important problem in the area of spatial database. Previous works focused on textual document with geo-tags, rather than geo-multimedia data such as geo-images. In this paper, we study a novel search problem named spatial visual similarity join (SVS-JOIN for short), which aims to find similar geo-image pairs in both the aspects of geo-location and visual content. We propose the definition of SVS-JOIN at the first time and present how to measure geographical similarity and visual similarity. Then we introduce a baseline inspired by the method for textual similarity join and a extension named SVS-JOIN$_G$ which applies spatial grid strategy to improve the efficiency. To further improve the performance of search, we develop a novel approach called SVS-JOIN$_Q$ which utilizes a quadtree and a global inverted index. Experimental evaluations on real geo-image datasets demonstrate that our solution has a really high performance.
Submarket Dynamics of Time to Sale

We argue that the rush to apply multiple regression estimation to time on the market (TOM) durations may have led to important details and idiosyncrasies in local housing market dynamics being overlooked. What is needed is a more careful examination of the fundamental properties of time to sale data. The approach promoted and presented here, therefore, is to provide an examination of housing sale dynamics using a step-by-step approach. We present three hypotheses about TOM: (i) there is nonmonotonic duration dependence in the hazard of sale, (ii) the hazard curve will vary both over time and across intra-urban areas providing evidence of the existence of submarkets and (iii) institutional idiosyncrasies can have a profound effect on the shape and position of the hazard curve. We apply life tables, kernel-smoothed hazard functions and likelihood ratio tests for homogeneity to a large Scottish data set to investigate these hypotheses. Our findings have important implications for TOM analysis.
Thermogravimetric Analysis Studies of Thermally-treated Glycerol Impregnated Poplar Wood

The effects of glycerol pretreatment and thermal modification on poplar wood was examined using thermogravimetric analysis (TGA). The total mass losses of thermally-treated samples before and after glycerol impregnation were studied. The thermal degradation process was divided into three stages based on natural breaks in the slope of the TGA curves. The set-on and set-off temperatures, mass loss, and activation energy (Ea) of each stage were compared. Pretreatment with 60% glycerol followed by thermal modification at 160 °C produced pronounced differences in the three decomposition stages. Fewer wood components were decomposed in the first stage in glycerol-pretreated wood, which suggested that the pretreatment had modified the wood components into more thermally stable substances. However, the mass losses were higher in the next stage, suggesting that the effect on thermal stability was limited. The Ea values of wood decomposition during the first stage were decreased, while those during the second and third stages were increased. These results illustrate the potential for using a glycerol pretreatment to alter the thermal stability of wood.
Peer Observation: A Reflective Model.

The purpose of this paper is to examine attitudes to peer observation, and to put the case for a more reflective approach. Peer observation is frequently carried out for purposes of appraisal or judgement of the observed, and this can be detrimental both to teacher confidence, and to a supportive teaching environment. Furthermore, this approach seems to have little value for active teacher development, since the focus is on being developed, rather than on self-awareness and self-development. Peer observation, therefore, should not be a vehicle for the evaluation of others on the basis of our assumptions, but a reassessment of those assumptions on the basis of their teaching. TO this end, I propose two active selfdevelopment models of peer observation, with suggestions for their possible implementation.
Effect of dietary protease supplementation and sex on dressing percentage and body conformation in broilers

This paper presents research results on the effect of protease on the dressing percentage of conventionally dressed carcass and body conformation in broiler chickens. Broiler diet was supplemented with 0.2% protease (group E-I) and 0.3% protease (group E-II), and protein content in the feed was reduced by 4% (E-I) and 6% (E-II) through a decrease in soybean meal content. Fast-growing Cobb 500 broilers were used for a 63-day fattening trial. Body conformation measurement included absolute carcass conformation measures (metatarsus length, keel length, breast depth, breast angle, thigh girth) and relative body conformation measures - conformation indices (body weight/metatarsus length, body weight/keel length, body weight/breast depth, body weight/thigh girth). Results showed a significant effect of sex on the dressing percentage of conventionally dressed carcass and all body conformation measures, whereas diet had a significant effect on the dressing percentage of conventionally dressed carcass and breast angle values. [Projekat Ministarstva nauke Republike Srbije, br. 31033: Sustainable Conventional and Revitalized Traditional Production of Value-Added Poultry Meat and Eggs]
Free Entry Bertrand Competition

This paper examines Bertrand competition under free entry, when firm size vis-a-vis market size is exogenously given. A free entry Bertrand Nash equilibrium (FEBE) exists if and only if relative market size is sufficiently large. Further, there is a unique coalition-proof Nash equilibrium price that corresponds to the minimum FEBE price, leads to average cost pricing for all active firms and is decreasing in market size.
Morphology of sodium salt of calf thymus DNA on mica, alumina, and silica surfaces: Effect of solvent and drying method

ABSTRACT Investigation of morphology of deoxyribonucleotide triphosphate (DNA) dried on different surfaces by atomic force microscopy (AFM) is important in DNA research that is focused on subjects of condensation for gene therapy, sizing, DNA mapping, and cancer examination. The solvent, the surface type, and the method of drying effect the morphology of DNA on solid surfaces. Ethanol and water were used as solvents, flat mica, silica, and alumina surfaces were used as the substrates in the present study. Different methods such as ambient air-drying, N2-forced flow regime drying, and freeze-drying have been applied to droplets of DNA solutions in water or ethanol on the substrates. Forced flow drying regime causes nonlinear DNA attachment on the surface and self-assembly. DNA vertical distance on mica surface was found to be 6 and 1.4 nm for DNA dried in ambient air from ethanol and water solutions, respectively. It was 1.6 nm for N2 flow drying of aqueous DNA solution on mica surface. It was 4.6, 4.6, and 1.99 nm for ambient, N2 flow, and freeze-dried aqueous DNA on alumina surfaces, respectively. Aqueous solution of DNA dried under N2 flow on silica surface had 0.8 nm vertical distance. The smallest standard deviation of 0.05 nm was observed for DNA dried under N2 flow on alumina surface.
DETECTION AND FLUX DENSITY MEASUREMENTS OF THE MILLISECOND PULSAR J2145−0750 BELOW 100 MHz

We present flux density measurements and pulse profiles for the millisecond pulsar PSR J2145−0750 spanning 37 to 81 MHz using data obtained from the first station of the Long Wavelength Array. These measurements represent the lowest frequency detection of pulsed emission from a millisecond pulsar to date. We find that the pulse profile is similar to that observed at 102 MHz. We also find that the flux density spectrum between ≈40 MHz to 5 GHz is suggestive of a break and may be better fit by a model that includes spectral curvature with a rollover around 730 MHz rather than a single power law.
Disruption of Phytoene Desaturase Gene using Transient Expression of Cas9: gRNA Complex

Engineered nucleases have emerged as a powerful tool for site specific gene manipulation in plants. Based on Clustered Regularly Interspersed Short Palindromic Repeats/CRISPR associated (CRISPR/Cas) system, engineered Cas9:gRNA complex can be used to cleave specific DNA sequences in the genome. In the present study, Nicotiana benthamiana Phytoene Desaturase (NbPDS) gene was targeted by CRISPR/Cas9 system. The plant codon optimized (pcoCas9) along with guided RNA (gRNA) was cloned in plant expression vector pGreen0029, to target NbPDS gene. The NbPDS gene was disrupted transiently by agroinfiltration of pcoCas9-gRNA complex. Visible albino spots were observed on agro-infiltrated leaves of N. benthamiana plants after 7 days of infiltration. The observed albino spots were analyzed through PCR amplification of gRNAtarget, fluorescent microscopy and chlorophyll contents measurements. Our results support the notion that CRISPR/Cas9 system is a swift, robust and useful tool for targeted gene disruption, deletion and editing. © 2016 Friends Science Publishers
Background electromagnetic noise characterization: the role of external and internal Earth sources

The Earth is surrounded by the ionosphere and magnetosphere that can roughly be seen schematically as two concentric shells. These two composed and inhomogeneous structured shells around the Earth selectively affect electromagnetic (EM) waves propagation. Both ionosphere and magnetosphere interact also with particles and waves coming from external sources, generating electromagnetic phenomena that in turn might become sources of EM waves. Conversely, EM waves generated inside the ionosphere remain confined at various altitudes in this region, up to a so-called critical frequency limit, depending on frequency, EM waves can escape out of the ionosphere and magnetosphere or get through. The EM waves generated inside the magnetospheric cavity mainly originate as a result of the electrical activity in the atmosphere. It is well known that also man-made sources, now widely spread on Earth, are a fundamental source of EM waves; however, excluding certain frequencies employed in power distribution and communication, man-made noise can be dominant only at local scale, near their source. According to recent studies, EM waves are also generated in the Earth’s lithosphere; these waves were sometimes associated with earthquake activity showing, on the Earth’s surface, intensities that are generally orders of magnitude below the background EM noise. In this review paper, we illustrate EM waves of natural origin and discuss their characterization in order to try discriminate those of lithospheric origin detectable at or near the Earth’s surface.
General and Specific Combining Ability Analysis for Yield and Some of Its Associated Characters in Late Sown Condition in Bread Wheat (Triticum aestivum L.em. Thell)

Wheat, a cereal crop which stands at prime position among cereals in terms of acreage, production and versatility in adaptation to wider range of agro-environmental situations. Wheat is the third most produced food grain in the world after maize and rice which stands second to rice as the main human feed and ahead of maize as maize is more extensively used for animal feed. It is staple food for more than one billion people of the country and also International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 7 Number 07 (2018) Journal homepage: http://www.ijcmas. com
Mechanisms of transparent exopolymer particles (TEPs) fouling on ultra-filtration and its reduction by PVDF/N-TiO2 HFM

Research was carried out on the mechanisms of membrane fouling. Among a variety of foulants, transparent exopolymer particles (TEPs), which play an important role in biofilm formation and membrane fouling, have been overlooked for many years due to their invisiblility. Here TEPs were first separated from Chlorella Vulgaris culture broth and quantified via Alcian Blue staining method as reported in the literature. Other characterizations included particle-sizedistribution and zeta potential measurements. Then the fouling characteristics of ultrafiltration membranes by TEPs were assessed. The fabricated and tested hollow fiber membranes included conventional polyvinylidene fluoride membrane (PVDF) and mixed matrix membranes with titanium dioxide (PVDF/P25) or nitrogen doped titanium dioxide (PVDF/N-TiO2) nanoparticles integrated into the PVDF matrix. Membranes were characterized by scanning electron microscopy (SEM) and fouling resistance evaluations were performed under dark or visible light irradiation conditions for comparison. A significant enhancement of fouling resistance was observed for PVDF/N-TiO2 membrane under visible light irradiation. The addition of TiO2 nanoparticles into the PVDF matrix apparently improved surface hydrophilicity and the nanoparticles could be activated under light, which contributed to the enhanced anti-fouling properties of the membrane.
Service - Oriented Challenges for Design Science: Charting the "E"-volution

This article links service-dominant (S-D) logic and design science to advance service system design, which is characterized by the indeterminacy of the design problems and outcome measures. Although much progress has been made in IT and IS toward service-orientation, these developments are often adaptations of goods-dominant (G-D) logic, rather than a full transition to a service orientation. In this paper, the “e”-volution of systems design, transitioning from G-D logic to S-D logic, is described and the IS design challenges implied by S-D logic are identified. To devise new, service-oriented modeling, methods and evaluation measurements, S-D logic endorses a fundamental shift in design thinking for design science from “bounded rationality” for problem solving to “expandable rationality” for design for the unknown.
Job satisfaction among nurses in Al-Qassim hospitals and primary health care centers, Saudi Arabia, 2016

Background: Job's satisfaction consists of a feeling of well-being, resulting from the interaction of several occupational aspects, and may influence the worker's relationship with the organization, clients and family. Hence, it becomes important than the quality of nursing care to reflect on this topic in depth. The current nursing shortage and high turnover are of great concern in the Kingdom of Saudi Arabia (KSA) because of its impact on the efficiency and effectiveness of any health-care delivery system. Objectives: To assess the level of job satisfaction among staff nurses working in Ministry of Health(MOH) hospitals and primary health care centers (PHC) in Al Qassim region. To prepare and implement an action plan according to the findings from the study. Methods: A descriptive crosssectional design is utilized in the current study. The study was conducted between 5542 nurses working in 20 hospitals and PHCs in Al Qassim region. Response rate is 18% and 1037 questionnaires were analyzed using factor analysis and correlation. Findings: Overall results show that the job satisfaction is found to be averagely satisfied. Accommodation level, administration, work condition, recognition, co-workers communications, educational activity, payment, vacation and leave are used to determine the job satisfaction. There is no correlation between demographic variables and job satisfaction among the staff nurses. Most of the staffs were not satisfied with the workload. Additionally, most of the nurses not satisfied with their weekly off, and they are not happy with their annual allowance. Conclusion: This study concluded that the majority of the nurses participated in the study are averagely satisfied in their job. Therefore, the administration needs more interventions to build the satisfaction of staff nurse for better nurse retention.
Checking Multi-domain Policies in SDN

Programmable Network like SDN allows administrators to program network nfrastructure according to service demand and custom-defined policies. Network olicies are interpreted by the centralized controller to define actions and rules to rocess the network traffic on devices that belong to a single domain. However, actual etworks are multi-domain where several domains are interconnected. Then, because DN controllers in a domain cannot define nor monitor policies in other domains, etwork administrators cannot ensure that their own policies, origin policies are being nforced by the domains not directly managed by them (i.e. foreign domains). e present AudiT, a multi-domain SDN policy verifier that identifies whether an rigin policy is enforced by foreign domains. AudiT comprises (1) model for network opology, policies, and flows, (2) an Audit protocol to gather information about the ctions performed by network devices to carry the flows of interest, and (3) a validation ngine that takes that information and detects security policy violations, and (4) an extension to the OpenFlow protocol to enable external auditing. This paper resents our approach and illustrates its application using an example considering ultiple SDN networks.
Social determinatns of health: contributions from European health and medical sociology

Uno de los principales temas de las investigaciones recientes de la sociologia medica o de la salud tiene que ver con los determinantes de la salud, o mas especificamente con las inequidades sociales en salud. Sociologos de la medicina o epidemiologos sociales europeos han realizado sustanciales aportes al respecto. En este articulo realizo una breve revision del actual estado de la cuestion sobre el gradiente social en salud, teniendo como referencia cinco aproximaciones complementarias: seleccion social, provision de servicios de salud, penurias en los primeros anos de vida, estilos de vida poco saludables, situaciones estresantes/ recursos materiales y psicosociales en al vida adulta. Esta ultima aproximacion se explicara de manera mas detallada en relacion con los efectos adversos rara la salud de las condiciones de trabajo y empleo. Se presentan, ademas, nuevas evidencias sobre la influencia que tienen el deterioro de las condiciones de trabajo sobre la salud fisica y mental, haciendo especial referencia a dos modelos sociologicos que dan cuenta de las situaciones de estres laboral: demanda-control y desajustes entre el esfuerzo y recompensas obtenidas. Por otra parte, se plantea la discusion de la relacion entre condiciones de trabajo y salud en la vida adulta en el contexto de dos hipotesis: la mediacion y la modificacion de hipotesis. Como conclusion, se plantea que en los ultimos anos se ha logrado un progreso importante de la subespecialidad de la sociologia medica o de la salud, y este nuevo conocimiento sociologico ya esta siendo aplicado en diferentes contextos de la salud y de la politica social.