Miracle-dz/UniFAR-FTUs huggingface dataset:
Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1.

OBJECT Oxidative stress contributes to secondary injury after spinal cord injury (SCI). The expression of heme oxygenase-1 (HO-1), which protects cells from various insults including oxidative stress, is upregulated in injured spinal cords. Mice deficient in Bach1 (Bach1-/-), a transcriptional repressor of the HO-1 and beta-globin genes, express high levels of HO-1 mRNA and protein in various organs. The authors hypothesized that HO-1 modulates the secondary injury process after SCI in Bach1(-/-) mice. METHODS Male C57BL/6 (wild-type) and homozygous Bach1(-/-) C57BL/6 mice were subjected to moderate SCI, and differences in hindlimb motor function, and electrophysiological, molecular biological, and histopathological changes were assessed for 2 weeks. RESULTS Functional recovery was greater, and motor evoked potentials were significantly larger in Bach1(-/-) mice than in wild-type mice throughout the observation period. The expression of HO-1 mRNA in the spinal cord was significantly increased in both mice until 3 days after injury, and it was significantly higher in Bach1(-/-) mice than in wild-type mice at every assessment point. Histological examination using Luxol fast blue staining at 1 day after injury showed that the injured areas were smaller in Bach1(-/-) mice than in wild-type mice. The HO-1 immunoreactivity was not detected in uninjured spinal cord, but 3 days postinjury the number of HO-1-immunoreactive cells was obviously higher in the injured area in both mice, particularly in Bach1(-/-) mice. The HO-1 was primarily induced in microglia/macrophage in both mice. CONCLUSIONS These results suggest that HO-1 modulates the secondary injury process, and high HO-1 expression may preserve spinal cord function in the early stages after SCI in Bach1(-/-) mice. Treatment that induces HO-1 expression at these early stages may preserve the functional outcome after SCI.
Fall Detection System using Accelerometer Principals with Arduino Development Board

Fall related accident and injury are one of the most common reasons to cause of death and hospitalization among elderly. Falls among older people become a major problem facing hospitals and nursing homes. An enhanced fall detection system is proposed for elderly person monitoring that is based on-body sensor. The on-body sensor which consists of accelerometer, GPS model and GSM model is used in this model. An accelerometer is connected with GPS and GSM instant messaging module which is real time and GPS is used for location purpose, portable, and wearable, low-cost and with high accuracy rate. This device can monitor the movements and send alerts in case of emergency. For seniors who prefer to stay at their homes and live independently, the device can communicate with care taker to request help if needed
Suppression of Amblyomma americanum (Ixodida: Ixodidae) for Short-Term Field Operations Utilizing Cypermethrin and Lambda-Cyhalothrin

ABSTRACT Tick-borne diseases pose significant risks to U.S. military personnel who conduct operations, both domestic and abroad. To determine the feasibility of protecting personnel from tick vectors during short-term field deployments, acaricides Cypermethrin (Demon WP, Syngenta, Greensboro, NC) and lambda-cyhalothrin (Surrender Pestabs, CSI, Pasadena, TX) were applied to plots within two separate field sites on Camp Blanding Joint Training Center in Starke, FL, from May to June 2011. We analyzed their effectiveness in reducing tick counts for 6 wk after application. In total, 8,193 ticks were identified and counted, of which >99% were a mix of nymphs and adult-stage Amblyomma americanum (L.). Our results indicate that both Cypermethrin and lambda-cyhalothrin were effective in significantly reducing tick numbers and preventing entry into treated plots for 6 wk after application. Thus, these two acaracides can be used to effectively suppress tick populations and provide residual protection in small geographic areas of recreation or public health significance.
On the question of colic: are answers beginning to emerge?

In EVJ’s last issue, Dr Martin Burton challenged the veterinary world to prepare and publish systematic reviews that will inform veterinary practice [1]. Dr Burton’s comments were in response to our publication of our first systematic review addressing interventions for dynamic intermittent dorsal displacement of the soft palate [2]. Clinicians looking for other, similarly robust pieces of evidence in relation to either surgical or medical interventions in the horse are likely to be rather disappointed. Nevertheless, in clinical and applied research relating to colic, numerous groups internationally are working on clinically relevant research questions relating to this major cause of equine mortality. Much early work on colic surgery was published in EVJ by Professor Barrie Edwards and his colleagues, eventually going on to establish a huge database on risk factors and outcome following colic surgery in general [3]. There is now a need to refine our questions about colic more specifically to build up evidence that will influence clinical practice.
Relaxation NMR as a tool to study the dispersion and formulation behavior of nanostructured carbon materials

Solvent relaxation NMR has been used to estimate the surface areas and wettability of various types of nanostructured carbon materials in a range of solvents including water, ethanol, and tetrahydrofuran. We illustrate the application of the technique through several short case studies using samples including nanocarbon blacks, graphene oxide, nanographites, and porous graphenes. The technique is shown to give a good measure of surface area, correlating well with conventional surface area estimates obtained by nitrogen adsorption, transmission electron microscopy, or light scattering for the non‐porous samples. NMR relaxation has advantages in terms of speed of analysis and being able to use concentrated, wet, and opaque samples. For samples that are porous, two distinct surface areas can be estimated assuming the two environments ('inner' and 'outer') have the same surface chemistry, and that there is a slow exchange of solvent molecules between them. Furthermore, we show that differences in wettability and dispersability between samples dispersed in water, ethanol, and cyclopentanone can be observed, along with changes to the surface chemistry of the interface. Copyright © 2015 John Wiley & Sons, Ltd.
Interactions of the Salience Network and Its Subsystems with the Default-Mode and the Central-Executive Networks in Normal Aging and Mild Cognitive Impairment

Previous functional magnetic resonance imaging (fMRI) investigations suggest that the intrinsically organized large-scale networks and the interaction between them might be crucial for cognitive activities. A triple network model, which consists of the default-mode network, salience network, and central-executive network, has been recently used to understand the connectivity patterns of the cognitively normal brains versus the brains with disorders. This model suggests that the salience network dynamically controls the default-mode and central-executive networks in healthy young individuals. However, the patterns of interactions have remained largely unknown in healthy aging or those with cognitive decline. In this study, we assess the patterns of interactions between the three networks using dynamical causal modeling in resting state fMRI data and compare them between subjects with normal cognition and mild cognitive impairment (MCI). In healthy elderly subjects, our analysis showed that the salience network, especially its dorsal subnetwork, modulates the interaction between the default-mode network and the central-executive network (Mann-Whitney U test; p < 0.05), which was consistent with the pattern of interaction reported in young adults. In contrast, this pattern of modulation by salience network was disrupted in MCI (p < 0.05). Furthermore, the degree of disruption in salience network control correlated significantly with lower overall cognitive performance measured by Montreal Cognitive Assessment (r = 0.295; p < 0.05). This study suggests that a disruption of the salience network control, especially the dorsal salience network, over other networks provides a neuronal basis for cognitive decline and may be a candidate neuroimaging biomarker of cognitive impairment.
A dynamic update of the HWMP proactive tree for IEEE 802.11s based wireless mesh networks

In this paper we propose a dynamic update of the HWMP (Hybrid Wireless Mesh Protocol) proactive tree by changing dynamically the path request (PREQ) transmission interval, instead of a periodic fixed value as defined in the IEEE 802.11s draft. Indeed, we adapt dynamically the value of the PREQ transmission interval according to the wireless environment characteristics and to the amount of traffic flows generated by applications within the considered environment. Thereby, we expect improving the routing table accuracy and minimizing the path recovery delays with less overhead for critical applications. Simulations results using Network Simulator 3 (NS-3) show that our proposed dynamic and non periodic PREQ transmission interval gives better results than a fixed periodic transmission interval value.
Interactive graphics for Data Analysis - Principles and Examples

Interactive Graphics for Data Analysis: Principles and Examples discusses exploratory data analysis (EDA) and how interactive graphical methods can help gain insights as well as generate new questions and hypotheses from datasets.Fundamentals of Interactive Statistical Graphics The first part of the book summarizes principles and methodology, demonstrating how the different graphical representations of variables of a dataset are effectively used in an interactive setting. The authors introduce the most important plots and their interactive controls. They also examine various types of data, relations between variables, and plot ensembles.Case Studies Illustrate the Principles The second section focuses on nine case studies. Each case study describes the background, lists the main goals of the analysis and the variables in the dataset, shows what further numerical procedures can add to the graphical analysis, and summarizes important findings. Wherever applicable, the authors also provide the numerical analysis for datasets found in Cox and Snells landmark book.This full-color text shows that interactive graphical methods complement the traditional statistical toolbox to achieve more complete, easier to understand, and easier to interpret analyses.
Different Brain Areas Are Involved in Memory Expression at Different Times from Training

Rats were trained in a step-down inhibitory avoidance task and tested for retention 1, 31, or 60 days later. Three to 7 days prior to testing, they were bilaterally implanted with cannulae in the CA1 region of the dorsal hippocampus and in the amygdaloid nucleus (H + A), in the entorhinal cortex (EC), and in the posterior parietal cortex (PPC). Ten minutes prior to testing, the animals received, through the cannulae, 0.5-microliter microinfusions of vehicle (20% dimethylsulfoxide in saline) or of 0.5 microgram of CNQX dissolved in the vehicle. A second test session was carried out 90 min after the first. CNQX blocked retention test performance when given into H + A 1 day after training but not later; when given into EC 1 or 31 days after training, but not later; and when given into PPC 1, 31, or 60 days after training. In all cases performance returned to normal levels in the second test session. The data suggest that H and A are involved in memory expression for only a few days after acquisition; that EC is involved in memory expression for up to 31, but less than 60, days after acquisition; and that PPC is involved in memory expression for up to at least 2 months after acquisition.
Ethical Decision Making in Software Piracy: Initial Development and a Test of a Four-Component Model

Software piracy costs the software industry billions of dollars each year. To better understand piracy, we propose a model of ethical decision making that is an adaptation of the four-component model of morality. This model defines four internal processes that result in external moral behavior: recognition, judgment, intention, and behavior. We test our model with a sample of Information Systems students in Hong Kong who provided measures of self-reported behavior regarding levels of buying and using pirated software. Using partial least squares, we investigated the causal pathways of the model and the effects of age and gender. We find that use is determined by buying, buying is determined by intention, and intention is determined by judgment. Although respondents recognized software piracy as an infringement of intellectual property rights, this fact did not affect their judgment of the morality of the act. Significant differences are also found in the ethical decision-making process based on age but only limited differences based on gender. The implications of these results, including the development of a professional ethics program, are discussed.
CIRCADECENNIAN PEAK EXPIRATORY FLOW AND THE PUTATIVE

Peak expiratory flow (PEF) can be self-measured. Self-measurements of PEF on a long-term basis permit assessment of the time structure of PEF and its relation to solar activity expressed in Wolf’s relative sunspot number. The results from a longitudinal record spanning 32.5 years were compared with four other shorter series. It appeared that the most prominent periodicity in the annual and infra-annual response of the spectrum was a component with a period of 11.74 years. This periodicity was comparable with the periodicity found for Wolf’s relative sunspot number (10.27) during the same span of time.
Multiuser adaptive subcarrier-and-bit allocation with adaptive cell selection for OFDM systems

Adaptive resource allocation has been identified as one of the key technologies for providing efficient utilization of the limited power and spectrum in future wireless systems. In this paper, an adaptive resource allocation methodology is proposed for cellular orthogonal frequency division multiplexing systems in a multiuser environment. The proposed method is featured as a low-complexity algorithm that involves not only adaptive modulation, but also adaptive multiple-access control and cell selection. Specifically, a multiuser subcarrier-and-bit loading scheme is developed to maximize the spectral efficiency. Besides, a dynamic cell selection scheme is proposed to deal with the problem of overloading and nonuniform traffic density. Numerical results show that the presented algorithm offers significant improvement in spectral efficiency due to the successful exploitation of channel variation, multiuser diversity, and inter-cell diversity.
Privacy Preserving Mining of Transaction Databases

In this paper, A company (data owner) lacking in expertise or computational resources can outsource its mining needs to a third party service provider (server) taking the advantage of cloud computing. However, a business can have many suppliers and/or customers and may have a set of transactions associated with each one and also the items in the outsourced database and the patterns of items that can be mined from the database are considered as the private property of the corporation (data owner). To protect the corporate privacy, the data owner transforms its data and ships it to the server. The server sends extracted patterns to the owner in response to the mining queries. The owner recovers the true patterns from the extracted patterns received. Here the problem of outsourcing the association rule mining task within a corporate privacy-preserving framework is studied. Proposed model based on background knowledge of Fast Encryption Algorithm (FEAL) Cryptosystem an encryption/decryption strategy for providing security and hence enabling privacy-preserving of outsourced mining task, and protection against the privacy violation attack.
A Clinico-Epidemiological Study of Macular Amyloidosis from North India

Background: Macular amyloidosis (MA) is the most subtle form of cutaneous amyloidosis, characterized by brownish macules in a rippled pattern, distributed predominantly over the trunk and extremities. MA has a high incidence in Asia, Middle East, and South America. Its etiology has yet to be fully elucidated though various risk factors such as sex, race, genetic predisposition, exposure to sunlight, atopy and friction and even auto-immunity have been implicated. Aim: This study attempts to evaluate the epidemiology and risk factors in the etiology of MA. Materials and: Methods: Clinical history and risk factors of 50 patients with a clinical diagnosis of MA were evaluated. Skin biopsies of 26 randomly selected patients were studied for the deposition of amyloid. Results: We observed a characteristic female preponderance (88%) with a female to male ratio of 7.3:1, with a mean age of onset of MA being earlier in females. Upper back was involved in 80% of patients and sun-exposed sites were involved in 64% cases. Incidence of MA was high in patients with skin phototype III. Role of friction was inconclusive Conclusion: Lack of clear-cut etiological factors makes it difficult to suggest a reasonable therapeutic modality. Histopathology is not specific and amyloid deposits can be demonstrated only in a small number of patients. For want of the requisite information on the natural course and definitive etiology, the disease MA remains an enigma and a source of concern for the suffering patients.
A Code-Based Packet Recovery Mechanism in Fiber-Wireless (FiWi) Access Networks

As a combination of fiber networks' huge available bandwidth and wireless networks' ubiquity and mobility, the fiber-wireless (FiWi) access network is considered as a promising network architecture for future networks. The wireless subnetwork of FiWi networks is responsible for users' Internet access and connected to back-end fiber subnetwork. Inheriting from pure wireless networks, the wireless subnetwork is also vulnerable to the factors in surrounding environment such as noise, mutual interference of different users and etc. Although fiber links are quite good, they are not perfect. When a fiber link is long enough, the signal fading can not be ignored which may make receiver receive a false packet. The interference in wireless subnetworks and the signal fading in fiber subnetworks severely affect the quality of service in FiWi networks. In this paper, a code-based packet recovery mechanism in FiWi access networks is proposed. Based on the XOR coding, a packet which contains recovery message is generated by sender after sending several normal packets. The recovery packet follows these normal packets. Our packet recovery mechanism makes the receiver be able to cope with the situation of one packet loss, rather than request the sender to retransmit. The recovery packet generating algorithm and the packet recovery algorithm are also presented. Through extensive numerical simulation, we discuss the cost of packet recovery mechanism and compare its performance with the alternative without packet recovery mechanism.
Hospitalizations in Pediatric and Adult Patients for All Cancer Type in Italy: The EPIKIT Study under the E.U. COHEIRS Project on Environment and Health ,

Background: Cancer Registries (CRs) remain the gold standard for providing official epidemiological estimations. However, due to CRs’ partial population coverage, hospitalization records might represent a valuable tool to provide additional information on cancer occurrence and expenditures at national/regional level for research purposes. The Epidemiology of Cancer in Italy (EPIKIT) study group has been built up, within the framework of the Civic Observers for Health and Environment: Initiative of Responsibility and Sustainability (COHEIRS) project under the auspices of the Europe for Citizens Program, to assess population health indicators. Objective: To assess the burden of all cancers in Italian children and adults. Methods: We analyzed National Hospitalization Records from 2001 to 2011. Based on social security numbers (anonymously treated), we have excluded from our analyses all re-hospitalizations of the same patients (n = 1,878,109) over the entire 11-year period in order to minimize the overlap between prevalent and incident cancer cases. To be more conservative, only data concerning the last five years (2007–2011) have been taken into account for final analyses. The absolute number of hospitalizations and standardized hospitalization rates (SHR) were computed for each Italian province by sex and age-groups (0–19 and 20–49). Results: The EPIKIT database included a total of 4,113,169 first hospital admissions due to main diagnoses of all tumors. The annual average number of hospital admissions due to cancer in Italy has been computed in 2362 and 43,141 hospitalizations in pediatric patients (0–19 years old) and adults (20–49 years old), respectively. Women accounted for the majority of cancer cases in adults aged 20–49. As expected, the big city of Rome presented the highest average annual number of pediatric cancers (n = 392, SHR = 9.9), followed by Naples (n = 378; SHR = 9.9) and Milan (n = 212; SHR = 7.3). However, when we look at SHR, minor cities (i.e., Imperia, Isernia and others) presented values >10 per 100,000, with only 10 or 20 cases per year. Similar figures are shown also for young adults aged 20–49. Conclusions: In addition to SHR, the absolute number of incident cancer cases represents a crucial piece of information for planning adequate healthcare services and assessing social alarm phenomena. Our findings call for specific risk assessment programs at local level (involving CRs) to search for causal relations with environmental exposures.
Novel multi-element resonant converters for front-end dc/dc converters

This paper proposes novel multi-element resonant converters for front-end dc/dc converters. The superior performance of the proposed resonant converters is to provide inherent current protection and very low circulating energy. With the optimized design, the proposed resonant converters can operate under short output circuit. Based on the third order harmonic injection, the circulating energy of the resonant tank can be reduced and lower than other conventional resonant converters, such as LLC resonant converters. Zero-voltage-switching (ZVS) and zero-current-switching (ZCS) can be achieved for primary side and secondary side devices respectively. Furthermore, high voltage gain can be designed for holdup time operation. The hold up time capacitors can be reduced more than 50% compared with conventional circuits. Hence, cost and volume can be saved significantly. Finally, a 1 kW, 1 MHz prototype is built to demonstrate the advantages of the proposed resonant converters. 86 W/in3 power density and 95.5% efficiency at full load are achieved.
Optimum Network Reconfiguration to Improve Power Quality and Reliability in Distribution System

In this paper, network reconfiguration has been conducted to improve the power quality and reliability of distribution systems in presence of distributed generations. In this case, network reconfiguration is analyzed for different indices. The most important indices are the number of propagated voltage sags (N sag), sustained average interruption frequency index, average system interruption frequency index and momentary average interruption frequency index. The Imperialist competitive algorithm (ICA) is hired to find the optimal configuration of the distribution system in order to minimize the mentioned indices. Simulation result is discussed with and without distributed generation.