Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of elastic strain energy on self-organized pattern formation

This paper studies the growth of self-organized quantum dots in strained semiconductors in the Stranski-Krastanov growth mode using the kinetic Monte Carlo simulation method. The four nearest and four next nearest neighbours of each atom in the square lattice grid with a periodic boundary condition are considered in the calculation of the binding energy among atoms. The elastic strain energy is accurately evaluated by the rigorous point eigenstrain half-space Green's function and is incorporated for the first time into the kinetic Monte Carlo model. The set of relevant growth parameters such as growth temperature, surface coverage, flux rate, and growth interruption time, is investigated and optimal values are identified. It is shown clearly that when the long-range elastic strain energy is included in the simulation, uniform size and ordered spatial distribution can be achieved. Furthermore, the growth of stacked quantum dot layers is also simulated briefly and vertical alignment is observed that could lead to progressively uniform island size and spatial ordering.
Research on Evaluation Method of Distribution Network State

In recent years, power grid assessments are more and more important with the continuous development of distribution network. Although much research has been done about evaluation method of medium voltage distribution network, it is hard to establish a united evaluation system of distribution network and the corresponding evaluation algorithm. Fuzzy comprehensive evaluation method has been used in this paper to assess the distribution network. Establishment of comprehensive evaluation matrix and fuzzy comprehensive evaluation can be done on the basis of established factors sets, evaluation sets, and weight sets. The evaluation score of each partition is obtained by single-value processing the result vector, as well as the analysis of regional distribution network running state rank and the influence factors in the region running state. Finally, the feasibility of this process is validated by assessing a regional distribution network.
author-version of: Role for ATXN1, ATXN2, and HTT intermediate repeats in frontotemporal dementia and Alzheimer's disease

We analyzed the frequency of intermediate alleles (IAs) in the ATXN1, ATXN2 and HTT genes in several neurodegenerative diseases. The study included 1,126 Alzheimer disease (AD), 440 frontotemporal dementia (FTD) and 610 Parkinson's disease (PD) patients. In all cohorts, we genotyped ATXN1 and ATXN2 CAG repeats. Additionally, in the FTD cohort we determined the number of HTT CAG-repeats. The frequency of HTT IAs was higher in FTD patients (6.9%) vs controls (2.9%) and in the C9orf72 expansion non carriers (7.2%) vs. controls (2.9%), although the difference was non-significant after correction for multiple testing. Compared to controls, progressive non-fluent aphasia (PNFA) groups showed a significantly higher frequency of HTT IAs ( 13.6% vs 2.9% controls) . For the ATXN2 gene, we observed an IAs increased frequency in AD cases (AD 4.1% vs controls 1.8%) and in the behavioural FTD (bvFTD) group (4.8% vs 1.8%). For the ATXN1 gene we found a significant increase of IAs in PNFA patients (18.6%) vs controls (6.7%). In conclusion, our work suggests that the HTT and ATXN1 IAS may contribute to PNFA pathogenesis and point to a link between ATXN2 IAS and AD.
SHORT COMMUNICATION Taxonomic notes on the genus Microfilistata (Araneae: Filistatidae), with a description of a new species from Turkmenistan

Microfilistata ovchinnikovi new species (Araneae: Filistatidae), the second member of this formerly monotypic Central Asian genus, is described from Kyzyl-Dzhar Ravine, Southern Turkmenistan. The genus is redescribed and referred to the Filistatidae insertae sedis.
Advances in Molecular Classification of Glioblastoma

G lioblastoma is the most common primary brain tumor, with an annual incidence of 3.19 per 100 000 in the United States.1,2 The current standard of care combines maximal surgical resection, followed by radiotherapy with concomitant and adjuvant temozolomide.3 Despite this multimodal approach, median survival is limited to 16 to 19 months, with approximately 25% to 30% of the patients alive at 2 years after diagnosis.1,3,4 Patients whose tumors display epigenetic silencing of the DNA repair enzyme O-methyl-guanine-methyltransferase experience better outcomes.4,5 In a recent phase 3 trial4 examining an intensified dosing regimen of temozolomide, patients with methylated O-methyl-guanine-methyltransferase promoter tumors achieved an overall survival length of 21 months vs 14 months for patients with unmethylated tumors and progression-free survival of 9 months vs 6 months. Unfortunately, glioblastoma progresses in all patients, regardless of the tumor’s molecular characteristics. At disease progression, traditional cytotoxic chemotherapy (carmustine, lomustine, or carboplatin) is of little help.1 Bevacizumab, a monoclonal antibody targeting angiogenesis through modulation of the vascular endothelial growth factor pathway, has received conditional approval from the US Food and Drug Administration based on 2 promising phase 2 studies6,7 that demonstrated high response rates (28.3%7 and 37.8%6) and prolonged progressionfree survival (16 weeks7), although improvements in overall survival remain to be demonstrated. More recently, 2 phase 3 studies8,9 combining bevacizumab with standard chemotherapy and radiotherapy in patients with newly diagnosed disease have found improved progression-free survival but not overall survival. Given the poor survival with currently approved treatments, new therapeutic options for glioblastoma are clearly needed. Fortunately, rapid advances are being made in understanding glioblastoma tumor genetics. The present review focuses on how these advances are being translated into innovative treatments currently being tested in clinical trials. A review published recently in JAMA1 focused on standard treatment and current trends in the routine clinical management of this disease. IMPORTANCE Glioblastoma is the most common primary malignant brain tumor, but despite multimodal treatment with surgery, radiotherapy, and temozolomide chemotherapy, the prognosis is poor, with a median survival of 16 to 19 months and poor quality of life throughout the disease course. New treatments are needed.
The Restoration of Textured Images Using Fractional-Order Regularization

Image restoration problem is ill-posed, so most image restoration algorithms exploit sparse prior in gradient domain to regularize it to yield high-quality results, reconstructing an image with piecewise smooth characteristics. While sparse gradient prior has good performance in noise removal and edge preservation, it also tends to remove midfrequency component such as texture. In this paper, we introduce the sparse prior in fractional-order gradient domain as texture-preserving strategy to restore textured images degraded by blur and/or noise. And we solve the unknown variables in the proposed model using method based on half-quadratic splitting by minimizing the nonconvex energy functional. Numerical experiments show our algorithm's robust outperformance.
Evaluation of natural sources for repress cytotoxic Trichothecenes and Zearalenone production with using Enzyme-linked immunosorbent assay

Even though the prevention of fungal growth is still the good practice to prevent contamination by mycotoxins, but there are a number of approaches that can be taken to minimize mycotoxins contamination in the food. The advantage of using-plant produced compounds and bioagent as a source of safer and more effective control substances than synthetically produced antimicrobial agents can be demonstrated both practically and in terms of consumer acceptance. Cinnamon and cyperus oils had antifungal activity against Alternaria alternata and Fusarium culmorum. Inhibition % of deoxynivalenol (DON) and Trichothecene (T-2) production was 21.89 and 42.83% respectively at 1.5 μL/ml of cinnamon oil. The extracts of the Aloe vera inhibit the production of Zearalenone and T-2 mycotoxins ranged from 9.13 to 17.15 and from 33.10 to 36.69% respectively. Strong effective of Adenium obesum extract on the inhibition production of ZER, DON and T-2 mycotoxins was reported, inhibition% was 39.15, 43.92 and 45.00 % at 20, 5 and 20 mg/ml respectively. Decrease of ZEA, DON and T-2 mycotoxins levels in comparison with the control (1083.43, 77.03 and 497.67 μg/kg respectively) was observed with Saccharomyces cerevisiae interaction (659.90, 42.92 and 294.26μg/kg respectively). T. harzianum inhibited the production of ZEA, DON and T-2 mycotoxins with an average inhibition of 25.06, 33.01 and 50.55% respectively. Our results improved that, the tested T. harzianum and S.cerevisiae had no toxic effects, seems to be a highly promising agent in preventing food contamination with F.culmorum and greatly inhibit mycotoxin production in vitro. [Abdel Ghany TM, Ganash MA, Marwah M. Bakri, Aisha M.H. Al-Rajhi, Mohamed A, Al Abboud. Evaluation of natural sources for repress cytotoxic Trichothecenes and Zearalenone production with using Enzyme-linked immunosorbent assay. Life Sci J 2016;13(8):74-86]. ISSN: 1097-8135 (Print) / ISSN: 2372-613X (Online). http://www.lifesciencesite. com. 13. doi:10.7537/marslsj130816.13.
The Problem Method in Teaching Philosophy: A Praxiologic Educology.

Professor Morkuniene ’s paper, in accord with the Recurring Editorial, represents directly one aspect of and indirectly two aspects of the domain of educology, and indirectly the do main of philosophy of educology, specifically the aspect of experiential philosophy of educology, in contrast to rationalistic, analytical, and phenomenological philosophies of educology. From the perspective of the editorial, the paper directly inquires with the experiential praxiologic educological question: What is the most effective way to teach philosophy involving educative experiences organically inhering in educational processes in developing democracies in the world?
Bottom-up and top-down control of bacterial community composition in the euphotic zone of a reservoir

Temporal changes in the bacterial community composition (BCC) and the impact of resources and predation on this community composition have been studied in the euphotic zone of the Sep reservoir (France), using terminal-restriction fragment length polymorphism (T-RFLP) and fluorescent in situ hybridization (FISH) for Eubacteria (EUB338) and eubacterial subgroups. Net growth and grazing rates of the various subgroups were computed from experiments conducted in dialysis bags in the presence or absence of predators. There was a significant difference between the grazing rates of different bacterial groups and subclasses, the alpha-proteobacteria (ALF1b) were subjected to the highest grazing rate (max. 1.76 d -1 ). In contrast, the beta-proteobacteria (BET42a) seemed to be little consumed by bacterivorous organisms, and predation led to large variations in the grazing rates of Cytophaga-Flavobacterium (CF319a). The different composition of bacterial con- sumers (Dinobryon sp. and Cladocera) during the study could explain the observed differences in grazing impact. The mean net growth rates of total bacteria, EUB338, BET42a ALF1b, and CF319a in dialysis bags without predators were 0.21, 0.69, 0.45, 0.50 and 0.84 d -1 , respectively. Various statisti- cal analyses indicated that the BCC could depend on the organic matter excreted by the phyto- plankton. There were also positive correlations not only between net growth and/or net production of ALF1b and CF319a with the primary production and biomass of the main phytoplankton groups, but also between phytoplankton biomass, primary production (PP) and some operational taxonomic units (OTUs). Among the physical variables, input and output of water in the reservoir seem to play a role in determining the BCC in this ecosystem. The results suggest that the BCC depends on the combined impact of dominant substrate sources and selective predation by bacterial consumers.
The power of website quality and perceived value of the consumer / seller relationship

Intensifying online loyalty! The power of website quality and perceived value of the consumer/seller relationship Wen-Chin Tsao Ming-Tsang Hsieh Tom M.Y. Lin Article information: To cite this document: Wen-Chin Tsao Ming-Tsang Hsieh Tom M.Y. Lin , (2016),"Intensifying online loyalty! The power of website quality and perceived value of the consumer/seller relationship", Industrial Management & Data Systems, Vol. 116 Iss 9 pp. Permanent link to this document: http://dx.doi. org/10.1108/IMDS-07-2015-0293
3934 DIXIT AND PUTHLI drying , and granulation processes

Journal of Pharm 2009 Wiley-Liss ABSTRACT: The concept of fluidization has been adapted to different unit processes of pharmaceutical product development. Till date a lot of improvements have been made in the engineering design to achieve superior process performance. This review is focused on the fundamental principles of aerodynamics and hydrodynamics associated with the fluidization technologies. Fluid-bed coating, fluidized bed granulation, rotor processing, hot melt granulation, electrostatic coating, supercritical fluid based fluidized bed technology are highlighted. Developments in the design of processing equipments have been explicitly elucidated. This article also discusses processing problems from the operator’s perspective along with latest developments in the application of these principles. 2009 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 98:3933–3960, 2009
outcome evaluation and manualization : adopting a learning organization approach The Adolescent Mentalization-based Integrative Treatment ( AMBIT ) approach to

AMBIT (Adolescent Mentalization-Based Integrative Treatment) is a developing team approach to working with hard-to-reach adolescents. The approach applies the principle of mentalization to relationships with clients, team relationships and working across agencies. It places a high priority on the need for locally developed evidence-based practice, and proposes that outcome evaluation needs to be explicitly linked with processes of team learning using a learning organization framework. A number of innovative methods of team learning are incorporated into the AMBIT approach, particularly a system of web-based wiki-formatted AMBIT manuals individualized for each participating team. The paper describes early development work of the model and illustrates ways of establishing explicit links between outcome evaluation, team learning and manualization by describing these methods as applied to two AMBIT-trained teams; one team working with young people on the edge of care (AMASS — the Adolescent Multi-Agency Support Service) and another working with substance use (CASUS – Child and Adolescent Substance Use Service in Cambridgeshire). Measurement of the primary outcomes for each team (which were generally very positive) facilitated team learning and adaptations of methods of practice that were consolidated through manualization.
A Pilot Study of Prenatal Care Visits Breanna Lathrop

Healthy Pregnancy, Healthy Childbirth, Healthy Parenting (HPCP) is a blended prenatal care model that integrates group visits with individual prenatal visits. While group prenatal care has been found to have a positive impact on pregnancy outcomes, current models may not be feasible or desirable in all clinical settings. HPCP off ers one educational group visit each trimester to improve knowledge of self-care during pregnancy and of childbirth and infant care. Th e program was piloted among women with low income in a southern metropolitan area. Th is article presents the fi ndings of a pilot study that examined maternal knowledge acquisition and subsequent changes in self-effi cacy and satisfaction with care. Suggestions for future use of a blended model for the delivery of prenatal care are shared. DOI: 10.1111/1751-486X.12159
Robotics and Autonomous Systems Experimenting with 3 D vision on a robotic head

We intend to build a vision system that will allow dynamic 3D perception of objects of interest. More specifically, we discuss the idea of using 3D visual cues when tracking a visual target, in order to recover some of its 3D characteristics (depth, size, kinematic information). The basic requirements for such a 3D vision module to be embedded on a robotic head are discussed. The experimentation reported here corresponds to an implementation of these general ideas, considering a calibrated robotic head. We analyse how to make use of such a system for (1) detecting 3D objects of interest, (2) recovering the average depth and size of the tracked objects, (3) fixating and tracking such objects, to facilitate their
Two-point spectral model for variable-density homogeneous turbulence

We present a study of buoyancy-driven variable-density homogeneous turbulence, using a two-point spectral closure model. We compute the time-evolution of the spectral distribution in wavenumber $k$ of the correlation of density and specific-volume $b(k)$, the mass flux $\bm{a}(k)$, and the turbulent kinetic energy $E(k)$, using a set of coupled equations. Under the modeling assumptions, each dynamical variable has two coefficients governing spectral transfer among modes. In addition, the mass flux $\bm{a}(k)$ has two coefficients governing the drag between the two fluids. Using a prescribed initial condition for $b(k)$ and starting from a quiescent flow, we first evaluate the relative importance of the different coefficients used to model this system, and their impact on the statistical quantities. We next assess the accuracy of the model, relative to Direct Numerical simulation of the complete hydrodynamical equations, using $b$, ${\bm a}$ and $E$ as metrics. We show that the model is able to capture the spectral distribution and global means of all three statistical quantities at both low and high Atwood number for a set of optimized coefficients. The optimization procedure also permits us to discern a minimal set of four coefficients which are sufficient to yield reasonable results while pointing to the mechanisms that dominate the mixing process in this problem.
Quelles études pour évaluer des nouveaux dispositifs médicaux ?

MOTS CLÉS Dispositif médical ; Évaluation ; Efficacité ; Complications ; Faisabilité ; Essai contrôlé randomisé Résumé Actuellement, les agences d’évaluation ont beaucoup de difficultés pour obtenir des preuves scientifiques de qualité pour la démonstration de l’efficacité clinique d’un nouveau dispositif médical (DM). Ces difficultés sont spécifiques aux DM et à l’environnement médical qui les utilise. Schématiquement le développement clinique d’un nouveau DM, comprend deux étapes : les études de faisabilité et les études pour la démonstration du bénéfice clinique. Les études de faisabilité sont proposées immédiatement à la suite de la phase préclinique. Le type d’études adaptées méthodologiquement ce sont les essais prospectifs non comparatifs pour répondre aux questions portant sur la sélection des patients, la mise au point de la technique d’implantation, l’efficacité clinique et les complications. La démonstration du bénéfice clinique repose sur la réalisation d’un essai contrôlé randomisé en prenant en compte les études de faisabilité. La construction de l’essai se fait à partir de la formulation d’un objectif principal clair, précis et pertinent. Les patients éligibles doivent correspondre à ceux pour lesquels ce nouveau DM est destiné dans la pratique courante. Le choix du groupe témoin correspond à la stratégie ou au traitement de référence qui est établi à partir des données de la littérature. Un seul critère de jugement principal est proposé en conformité avec l’objectif principal qui doit être clinique (à chaque fois que cela est possible), pertinent et validé. La mesure du critère de jugement doit être la plus objective possible. Les essais sont préférentiellement multicentriques pour faciliter le recrutement des patients afin d’obtenir une période d’inclusion la plus brève possible. Enfin, le caractère multicentrique rend plus facile l’extrapolation des résultats de l’étude. Cependant, les équipes susceptibles de participer à un essai multicentrique doivent avoir stabilisé leur courbe d’apprentissage. La recherche clinique pour répondre aux exigences méthodologiques des essais cliniques de tout nouveau DM a besoin de se structurer, notamment en favorisant le rapprochement entre le monde industriel, les cliniciens et l’université. © 2009 Elsevier Masson SAS. Tous droits réservés.
Epithelial Interactions and Mucosal Homeostasis − Leukocyte

Many common inflammatory disorders are characterized by the infiltration of neutrophils across epithelial lined (mucosal) surfaces resulting in disruption of critical barrier function that protects from microbes and noxious agents. In such conditions, disease symptoms are complex but directly related to leukocyte effects on the barrier and epithelial cell function. It is now highly regarded that cellular factors such as cytokines and receptor– ligand interactions mediating adhesion of leukocytes to epithelial cells have potent effects on epithelial homeostasis, defined by coordinated proliferation, migration, differentiation, and regulated cell shedding. Certain cytokines, for example, not only alter leukocyte interactions with epithelia through changes in expression of adhesion molecules but also affect barrier function through alterations in the composition and dynamics of intercellular junctions. In particular, inflammation-induced loss of many tight junction molecules, in part, can account for dysregulated cellular proliferation, migration, survival, and barrier function. This review will highlight how neutrophils interact with epithelial cells with particular focus on adhesion molecules involved and signaling events that play roles in regulating mucosal homeostasis and pathobiology. A better understanding of these molecular events may provide new ideas for therapeutics directed at attenuating consequences of pathologic inflammation of mucosal surfaces.
FEAR OF THE FUTURE AND FUTUROLOGICAL ORIENTATIONS OF STUDENTS-The future is not a gift,it is an achievement.

In this research the author starts from the two hyptheses that rapid changes and contemporary reality bring fear of the future to which not even students are immune, and that among students we can recognize different value orientations in relation to the past, present and future. From a sample of 189 students of Pedagogy and Teacher Education Department, it is observed that over 80% of them show certain degree of fear, whereas a factor analysis has presented that the fear is latently generated by three components: contemplation of the future, global processes and taking over the responsibility for one's own long-term goals.