Miracle-dz/UniFAR-FTUs huggingface dataset:
Integrated, Collaborative Palliative Care in Heart Failure: The St. George Heart Failure Service Experience 1999–2002

Background:Chronic heart failure (HF) is the only heart condition increasing in prevalence and is primarily a condition of aging. This condition has outcomes worse than many cancers; however, patients are often denied the benefits of palliative care with its important emphasis on symptom management, spirituality, and emotional health and focus on family issues. Aim:To describe the development of a model of an integrated, consultative, palliative care approach within a comprehensive HF community-focussed disease management program. Method:A collaborative model was developed following a systematic needs assessment and documentation of local resources. Principles underpinning this model were based upon fostering of communication, consultancy, and skill development. Within this model a health care system, based upon universal coverage, supported co-management of patients and their families. The place of death, level of social support available at home, and degree of palliative care involvement was documented in 121 consecutive deaths from 1999–2002. Findings:Following a period of skill sharing and program development, only 8.3% of HF patients in the collaborative program required specialized palliative care intervention for complex symptom management, carer support, and issues related to spirituality. Twenty percent of this cohort died in nursing homes underscoring the importance of supporting our nursing colleagues in this setting. Conclusions:In spite of well-documented difficulties in determining prognosis, it is the St George experience that key principles of a palliative care strategy can be implemented in a HF disease management program with support and consultancy from expert palliative care services.
Estimation of the degree of crystallinity in digoxin by X‐ray and infrared methods

The X‐ray procedure for estimation of the degree of crystallinity in digoxin is based upon measurement of the total X‐ray scattering and the scattering from crystalline regions of the drug. The infrared procedures are based upon measurement of the peak height ratios, 1775/1618 and 3095/1618 cm−1. Correlation between results obtained by the two methods is good. These methods are of value in the physico‐chemical characterization of digoxin, particularly as the properties may be altered by comminution.
E-commerce: new forms of work for wealth creation in Zimbabwe

In the present scenario of the technological world, business is being conducted locally and internationally using electronic means with ease. E-commerce has provided new forms of work in various sectors such as transport, warehousing, insurance, banking, mining, agriculture and communication . However, it is difficult to purchase a product or service online. E- commerce compromises privacy and consumers tend to lose confidence. This paper will highlight the new forms of work in Ecommerce in Zimbabwe.
Factors Determining Cognitive Dysfunction in Cerebral Small Vessel Disease

Introduction: Vascular dementia consists of cognitive and functional impairment due to cerebrovascular brain injury. With reference to small vessel disease (SVD), even though the radiological evidence of SVD is present in a large number of persons above the age of 80 years, less than one-third of the people progress to dementia. Hence, if those factors are identified, we may be able to formulate strategies to protect that percentage of patients who progress to dementia. In this study, we have analyzed some genetic and nongenetic factors in patients with and without a cognitive impairment in the presence of radiological SVD. Patients and Methods: Two hundred and ten patients who satisfied the criteria for the study were included. All medical comorbidities, demographic factors, substance abuse, etc., were documented and neuropsychological evaluation done. In addition, the genetic testing was done for the polymorphisms of TT, TC, and CC alleles of CYP11B2 based on the literature evidence of the association of CYP11B2 polymorphism and hypertension. Results: This prospective hospital-based study revealed a significant relationship among hypertension, hyperhomocysteinemia, and severity of white matter changes but other comorbidities did not correlate. No significant correlation was seen between cognitive dysfunction and severity of white matter changes or genotypes TT, TC, and CC. However, TC genotype was more common in male hypertensives. Even though hypertension and hyperhomocysteinemia were associated with leukoaraiosis, none of the factors studied trigger conversion of these radiological changes to clinical cognitive impairment. Discussion and Conclusion: Severity of cerebral white matter changes seems to correlate with hypertension and hyperhomocysteinemia, however, none of the co-morbidities studied including the three polymorphisms of CYP11B2, that is, TT, TC, and CC seem to determine the conversion of leukoaraiosis to dementia.
Combining User Contexts and User Opinions for Restaurant Recommendation in Mobile Environment

In a mobile setting, user preferences vary in different contexts. Advances in mobile technologies have made the collection of user context information feasible, and as a result, the context-aware mobile recommender system field has been formed. Although there exist several different approaches to incorporating context into the recommendation process, context-aware recommendations are still difficult to compute. It is unclear which contextual factors are important and to which degree they influence user-item selection decisions. In this paper, the authors design a novel mobile restaurant recommender system combining user contexts and user opinions to provide restaurants to mobile users. This system extracts restaurant features from online user reviews and calculates the polarity of them based on sentiment analysis. It takes a new approach for assessing and modeling the relationship between contextual factors and restaurant features. On this basis, a hybrid recommender method is constructed, which integrates the contextual matching algorithm based on analytic hierarchy process and the collaborative filtering algorithm based on context similarity. From the user study, this system suggests restaurants that make the user more satisfied than another comparative system.
Design and power consumption simulation of an electonic textile in two conditions

In this paper a long life design of a wearable electronic textile for a special application is presented. Specifications of some real low power, tiny elements including sensors, microcontrollers, transceivers, and a fault tolerant special topology are used to increase reliability and decrease power consumption which will result in longer lifetime. Two conditions including normal and bodily critical conditions are considered. Total lifetime of the system in case of having just one and two processing nodes is compared. Simulation results show a considerable increase of the lifetime comparing with other studied methods as a result of prioritizing of activating elements. The total lifetime of the presented design in normal condition will be about 18 days for one processing node and more than 23 days for two processing nodes.
Superoxide anions produced by Streptococcus pyogenes group A-stimulated keratinocytes are responsible for cellular necrosis and bacterial growth inhibition

Gram-positive Streptococcus pyogenes (group A Streptococcus or GAS) is a major skin pathogen and interacts with keratinocytes in cutaneous tissues. GAS can cause diverse suppurative and inflammatory infections, such as cellulitis, a common acute bacterial dermo-hypodermitis with a high morbidity. Bacterial isolation yields from the lesions are low despite the strong local inflammation observed, raising numerous questions about the pathogenesis of the infection. Using an in vitro model of GAS-infected keratinocytes, we show that the major ROS produced is the superoxide anion ( O 2 - ), and that its production is time- and dose-dependent. Using specific modulators of ROS production, we show that O 2 - is mainly synthesized by the cytoplasmic NADPH oxidase. Superoxide anion production leads to keratinocyte necrosis but incomplete inhibition of GAS growth, suggesting that GAS may be partially resistant to the oxidative burst. In conclusion, GAS-stimulated keratinocytes are able to develop an innate immune response based on the production of ROS. This local immune response limits GAS development and induces keratinocyte cell death, resulting in the skin lesions observed in patients with cellulitis.
Hybrid control for vision based Cart-Inverted Pendulum system

This paper presents a vision based cart-inverted pendulum (CIP) system under a hybrid feedback configuration: the continuous cart's position measured by encoder and the delayed & sampled inverted pendulum's upper coordinates, obtained from a visual sensor. The challenge here is to stabilize the CIP from a big inclined initial angle by using a low cost CCD camera. Under this scheme, we propose a hybrid control which consists in a jumping-up (bang-bang) control and a two causal stabilization loops control: the first one (inner loop) realizes a linearization and the stabilization control of the pendulum based on an innovative piecewise continuous reduced order Luenberger observer (PCROLO) coupled with a linearization module, the second one (the outer loop) realizes a Lyapunov based control for the unstable internal system with lower dynamics than that of the pendulum. This hybrid control method is capable of balancing the CIP system within small cart's displacement. Performances issues of the proposed method are illustrated by the experimental figures and videos.
The quadruped robot locomotion based on force control

The quadruped robot can achieve stable locomotion with contact force control. The crucial technique of it is to convert the control of the center of mass (COM) to the control of supporting legs. In this paper, we propose a force distribution and control strategy based on model decomposition and optimal contact constrains for the quadruped robot with trotting gait. The quadruped robot can be modeled as a virtual planar seven-link and a virtual planar three-link under the supposition that the control of the COM is decoupled. Meanwhile, an optimal contact constraint will be proposed and the desired contact force can be found. The simulation and experiment results show that the robot can track the desired trajectories exactly and steadily.
Rickettsia conorii Indian Tick Typhus Strain and R. slovaca in Humans, Sicily

Suggested citation for this article: Torina A, Fernandez de Mera IG, Alongi A, Mangold AJ, Blanda V, Scarlata F, et al. Rickettsia conorii Indian tick typhus strain and R. slovaca in humans, Sicily [letter]. Emerg Infect Dis [serial on the Internet] 2012 Jun [date cited]. http://dx.doi. org/10.3201/eid1806.110966
Multiple Fault Testing of Large Circuits by Single Fault Test Sets

A general theory is presented in this paper to quantitatively predict the multiple fault coverage capability of single fault detection test sets in combinational circuits. The theory is unique in that it provides greatest lower bounds on the coverage capability of all possible circuits of concern by a simple table-look-up process. All the results known so far in this area are seen to be special cases of the theory. The more important contribution of the theory, however, is seen in its predictions made for reconvergent internal fan-out circuits. Most unexpectedly, the multiple fault coverage of such circuits by single fault test sets is discovered to be extremely precarious. Such results clearly have alarming implications in LSI and VLSI testing.
Interprofessional education in anatomy: Learning together in medical and nursing training

Teamwork and the interprofessional collaboration of all health professions are a guarantee of patient safety and highly qualified treatment in patient care. In the daily clinical routine, physicians and nurses must work together, but the education of the different health professions occurs separately in various places, mostly without interrelated contact. Such training abets mutual misunderstanding and cements professional protectionism, which is why interprofessional education can play an important role in dismantling such barriers to future cooperation. In this article, a pilot project in interprofessional education involving both medical and nursing students is presented, and the concept and the course of training are described in detail. The report illustrates how nursing topics and anatomy lectures can be combined for interprofessional learning in an early phase of training. Evaluation of the course showed that the students were highly satisfied with the collaborative training and believed interprofessional education (IPE) to be an important experience for their future profession and understanding of other health professionals. The results show that the IPE teaching concept, which combines anatomy and nursing topics, provides an optimal setting for learning together and helps nurses and doctors in training to gain knowledge about other health professionals' roles, thus evolving mutual understanding. Anat Sci Educ 8: 324–330. © 2014 American Association of Anatomists.
THE EFFECTS OF THERMAL RADIATION AND NON-UNIFORM HEAT SOURCE / SINK ON STRETCHING SHEET EMBEDDED IN NON-DARCIAN POROUS MEDIUM

The Numerical analysis of magneto-hydrodynamics (MHD) boundary layer flow and heat transfer of incompressible, viscous and electrically conducting fluid is presented. The flow is due to continuously stretching permeable surface embedded in non-Darcian porous medium in the presence of transverse magnetic field, thermal radiation and non-uniform heat source/sink. The flow equations in the porous medium are governed by ForchheimerBrinkman extended Darcy model. A similarity transformation is used to transform partial differential equations into a coupled higher order non-linear ordinary differential equations. These equations are solved numerically using implicit finite difference scheme called Keller-Box method. The effects of the governing parameters on velocity and temperature are computed, analyzed and discussed. Moreover, the numerical results for the local skin friction coefficient and local Nusselt number are computed for various physical parameters governing the flow problem. It is found that increasing Darcy number accelerates the flow but increasing Forchhiemer number causes deceleration in the flow. The findings of the present study reveal that an increase in the radiation, heat source and Forchheimer number increases the thermal boundary layer thickness. The results under the limiting case were compared with the previously published work and found to be in good agreement.
Variable structure control of discrete uncertain system with time-delays

The original discrete uncertain system with time-delay is simplified to a discrete uncertain system without time-delay and a switching function is designed in which the movement of system is asymptotically stable. Then a variable structure controller is designed, which can force the system trajectory arrive at the quasi-switching manifold in limited steps and can traverse the switching manifold each step and can decreasingly approach to zero. Finally, Effectiveness of the proposed control method is demonstrated by simulation example.
An automatic intonation tone contour labelling and classification algorithm

Automatic recognition and classification of intonation contours in natural speech has the potential to improve the performance and useability of speech recognition systems, particularly those employed in automated speech response applications. The role of intonation in signalling meaning in natural English speech is well understood by linguists, and has been incorporated into the functional systemic grammar model of language. In this paper we describe the first stage of the development of a rule-based algorithm for intonation contour labelling and recognition which takes as its data input a stylised piecewise-linear approximation to the speech pitch contour. A key feature of the algorithm is the use of perceptually-based weighting of the segmented contour. Our results show good correspondence between the results of the automatic contour matching process and that of an expert human listener for a wide range of contours. <<ETX>>
Statistics of cosmological gamma-ray bursts.

A phenomenological model of gamma-ray burst spectra is used to calculate the statistics of gamma-ray bursts originating at cosmological distances. A model of bursters with no source evolution in a q sub 0 = 1/2 Friedmann cosmology is in accord with recent observations of the differential V/Vmax distribution. The data are best fit with an average peak-burst luminosity of (4 +/- 2) x 10 exp 51 ergs/s and a present-day source emissivity of 940 +/- 440 bursts/(10 exp 10 yr) cu Mpc. A spectral test of the cosmological hypothesis is proposed.
A simulation-calibrated limit on the H i power spectrum from the GMRT Epoch of Reionization experiment

The Giant Metrewave Radio Telescope Epoch of Reionization experiment is an ongoing effort to measure the power spectrum from neutral hydrogen at high redshift. We have previously reported an upper limit of (70 mK)^2 at wavenumbers of k ≈ 0.65 h Mpc^(−1) using a basic piecewise-linear foreground subtraction. In this paper, we explore the use of a singular value decomposition to remove foregrounds with fewer assumptions about the foreground structure. Using this method, we also quantify, for the first time, the signal loss due to the foreground filter and present new power spectra adjusted for this loss, providing a revised measurement of a 2σ upper limit at (248 mK)^2 for k = 0.50 h Mpc^(−1). While this revised limit is larger than previously reported, we believe it to be more robust and still represents the best current constraint on reionization at z ≈ 8.6.
Hubungan Kepuasan Pasien Pengguna BPJS Terhadap Kualitas Pelayanan Kesehatan di Puskesmas Nagrak Sukabumi

Health is a basic human need to be able to live decently and productively, so that, it is necessary to implement health care which the costs and the quality are controlled.As stated in the law No. 36 of 2009 on Health, it is affirmed that every person has the same right to access or get resources in the field of health and health services that are safe, high quality, and affordable.One of the goals of improving the quality of health care is patient’s satisfaction. Satisfaction is a happy or disappointed feeling of someone who emerged after comparing the impression of the performance or results of products and expectations.There are two components that will affect the level of patient’s satisfaction, they are the expectation components of the patient and health service performance components. Measuring the patient’s satisfaction is not easy, as it attempts to obtain necessary information to measure the level of patient’s satisfaction will be faced with a cultural obstacle, namely the presence of a tendency for people who are reluctant or unwilling to express criticism, moreover towards the governmental health care facilities.The purpose of this study was to determine BPJS user patients’ satisfaction to quality of health services at Puskesmas in Nagrak Sukabumi.This is ananalitic study with cross sectional approach, with a sample of 100 respondents who are BPJS user and non-user patients who ever got treatment at Puskesmas in Nagrak Sukabumi.Data analysis by using chi-square test. Bivariate test shows that, overall, there is a significant correlation between BPJS user and non-user patients’ satisfaction to quality of health services with p value of 0.000 (p <0.05), from 5 dimensions showed a significant relationship between BPJS user and non-user patients’ satisfaction on the reliability dimension (0.002), responsiveness (p = 0.004), empathy (p = 0.003), assurance (p = 0.014) and no significant relationship exists in the dimension of tangibles (p = 0.220).
Comprehensive MicroRNA expression profiling identifies novel markers in follicular variant of papillary thyroid carcinoma.

BACKGROUND Follicular variant of papillary thyroid carcinoma (FVPTC) shares features of papillary (PTC) and follicular (FTC) thyroid carcinomas on a clinical, morphological, and genetic level. MicroRNA (miRNA) deregulation was extensively studied in PTCs and FTCs. However, very limited information is available for FVPTC. The aim of this study was to assess miRNA expression in FVPTC with the most comprehensive miRNA array panel and to correlate it with the clinicopathological data. METHODS Forty-four papillary thyroid carcinomas (17 FVPTC, 27 classic PTC) and eight normal thyroid tissue samples were analyzed for expression of 748 miRNAs using Human Microarray Assays on the ABI 7900 platform (Life Technologies, Carlsbad, CA). In addition, an independent set of 61 tumor and normal samples was studied for expression of novel miRNA markers detected in this study. RESULTS Overall, the miRNA expression profile demonstrated similar trends between FVPTC and classic PTC. Fourteen miRNAs were deregulated in FVPTC with a fold change of more than five (up/down), including miRNAs known to be upregulated in PTC (miR-146b-3p, -146-5p, -221, -222 and miR-222-5p) and novel miRNAs (miR-375, -551b, 181-2-3p, 99b-3p). However, the levels of miRNA expression were different between these tumor types and some miRNAs were uniquely dysregulated in FVPTC allowing separation of these tumors on the unsupervised hierarchical clustering analysis. Upregulation of novel miR-375 was confirmed in a large independent set of follicular cell derived neoplasms and benign nodules and demonstrated specific upregulation for PTC. Two miRNAs (miR-181a-2-3p, miR-99b-3p) were associated with an adverse outcome in FVPTC patients by a Kaplan-Meier (p < 0.05) and multivariate Cox regression analysis (p < 0.05). CONCLUSIONS Despite high similarity in miRNA expression between FVPTC and classic PTC, several miRNAs were uniquely expressed in each tumor type, supporting their histopathologic differences. Highly upregulated miRNA identified in this study (miR-375) can serve as a novel marker of papillary thyroid carcinoma, and miR-181a-2-3p and miR-99b-3p can predict relapse-free survival in patients with FVPTC thus potentially providing important diagnostic and predictive value.
Reduced Apoptosis in Human Intestinal Cells Cured of Persistent Poliovirus Infection

ABSTRACT Cells cured of persistent virus infection can be used to investigate cellular pathways of resistance to viral cytopathic effects. Persistent poliovirus (PV) infections were established in human intestinal Caco-2 cells, and spontaneously cured cell cultures were obtained. Two cell clones, cl6 and b13, cured of type 3 PV mutant infection and their parental Caco-2 cells were compared for susceptibility to PV infection, PV receptor CD155 expression, capacity to differentiate into polarized enterocytes, and PV-, staurosporine-, and actinomycin D-induced apoptosis. Our results strongly suggest that cells that are partially resistant to apoptosis can be selected during persistent virus infection.