Miracle-dz/UniFAR-FTUs huggingface dataset:
Novel pre-vascularized tissue-engineered dermis based on stem cell sheet technique used for dermis-defect healing

Abstract Insufficient donor dermis and the shortage of three-dimensional vascular networks are the main limitations in the tissue-engineered dermis (TED). To solve these problems, we initially constructed pre-vascularized bone marrow mesenchymal stem cell sheet (PBMCS) and pre-vascularized fibroblasts cell sheet (PFCS) by cell sheet technology, and then superimposed or folded them together to construct a pre-vascularized TED (PTED), aiming to mimic the real dermis structure. The constructed PTED was implanted in nude mice dorsal dermis-defect wound and the wound-healing effect was quantified at Days 1, 7 and 14 via the methods of histochemistry and immunohistochemistry. The results showed that PTED could rapidly promote the wound closure, especially at Day 14, and the wound-healing rate of three-layer PTED could reach 97.2% (P < 0.01), which was faster than the blank control group (89.1%), PBMCS (92.4%), PFCS (93.8%) and six-layer PTED (92.3%). In addition, the vessel density in the PTED group was higher than the other groups on the 14th day. Taken together, it is proved that the PTED, especially three-layer PTED, is more conducive to the full-thickness dermis-defect repair and the construction of the three-dimensional vascular networks, indicating its potential application in dermis-defect repair.
ATRIBUTOS FÍSICOS E BALANÇO HÍDRICO DO SOLO COM FLORESTA OMBRÓFILA MISTA, EM LATOSSOLO VERMELHO-AMARELO, EM TELÊMACO BORBA - PR

The objective of this study was to characterize the soil physical and hydric attributes and quantify, in one year, the water balance components, carried out for Native Ombrophylous Forest, in an OXISOL, sandy texture, in Telemaco Borba - PR state. The experiment was held at Monte Alegre Farm, which belongs to the company Klabin Florestal, the area was under native forest in an advanced state of regeneration. The following physical and hydric attributes were characterized: bulk density, saturated hydraulic conductivity, soil water retention curve, aeration porosity and total available water ( TAW ). The undisturbed samples were collected in a trench, in five depths. The disturbed samples were collected weekly, in eight different points inside the experiment area, in five depths. The values of soil moisture and internal precipitation were collected and registered throughout the year. The soil water storage was calculated using the trapezoidal rule. The internal drainage and capillary rise were estimated by using the Darcy-Buckingham equation. The values of the bulk density, micro, macro and total porosity of the soil are classified in the range considered adequate for soils with sandy texture. The soil presented a high hydraulic conductivity, which is a characteristic of well drained soils. In average, the storage did not reach the permanent wilting point throughout the year. The average deep drainage was bigger throughout the months with more precipitation, the value being an average of 94.9 mm year –1 . The average value of the real evapotranspiration was 1355.9 mm year - 1 , an average of 3.7 mm day - 1 .
Leaving ‘home?’ Belonging, break-up and becoming in the police family

This article considers the impact of police merger processes on officers and staff. The Railway Policing (Scotland) Act 2017 legislated that the Scottish functions and personnel of the British Transport Police (BTP) would be integrated into Scotland’s national police force. The journey towards this destination, however, has been protracted, problematic and now appears to be indefinitely postponed. Demonstrating the limits of the ‘police family’, our research provides important policy insights, demonstrating how a failure to account for distinct organizational cultures and occupational identities can damage the legitimacy of police mergers. Using data from a survey of BTP officers and staff in Scotland, we present our findings across three themes: belonging; break-up and becoming. We refract these findings through Bourdieusian theory.
A large new species of Rhinella (Anura: Bufonidae) from Cerrado of Brazil

A new toad, Rhinella cerradensis, is described, including its tadpole and the advertisement call. The new species occupies Cerrado habitats in the Brazilian states of Piaui, Bahia, Goias, Minas Gerais, and Distrito Federal. The species is characterized by its large size; absence of tibial glands; well developed cranial crests; short hands; sexually dimorphic coloration; and by the absence of a spiracle tube of the tadpole. The new species is included in the Rhinella marina group by the presence of a jagged suture formed by the articulation between the pterygoid medial ramus and the parasphenoid alae, as well as other shared morphological features. Morphological characters and statistical analyses inferred by morphometric feature suggest the existence of two subgroups of species within R. marina group. However, taxonomic rearrangements are not made here and await phylogenetic analysis.
Invasion in BMP2-induced EMT is mediated through down-regulation of PI-3 Kinase/Akt pathway.

C38 Bone morphogenetic protein (BMP), a member of the transforming growth factor beta super-family, has been shown to be involved in development, morphogenesis, cell proliferation and apoptosis of a variety of tissues and cells. Although dysregulation of BMP signaling has been linked to various types of cancers, the relationship between abnormal activation of these signaling and tumorigenesis is not clear. Herein we sought to clarify how BMP2 is involved in aggressiveness of gastric cancer. Wound healing and Matrigel invasion assays showed that BMP2 strongly enhanced motility and invasiveness in gastric cancer cells, whereas no increase was observed in cells treated with Noggin (a BMP2 inhibitor). Aberrant elevation of BMP2 expression is highly correlated with the decrease in E-cadherin expression in the invasive human gastric cancer. Blocking of BMP2 signaling by Noggin restored E-cadherin expression in the cancer cells. This BMP2-induced epithelial to mesenchymal transition (EMT) and invasion results from down-regulation of phosphatidylinositol 3-Kinase (PI-3 Kinase)/Akt pathway. Blockade of the Akt kinase using kinase-dead Akt or LY294002 in the presence of BMP2 significantly enhanced the BMP2-induced EMT and cell motility/invasiveness. However, the cells transfected with AktMyr inhibited BMP2-induced EMT and migration/invasiveness by treatment with BMP2. Overall, our studies suggest that invasion in BMP2-induced EMT is mediated through down-regulation of PI-3 Kinase/Akt pathway.
Spatial Repellency and the Field Evaluation of a Push-Pull Strategy for the Control of Malaria Vectors in Northern Belize, Central America

Abstract : Mosquito-borne diseases represent one of the most significant threats to human health worldwide, with hundreds of millions of infections resulting in extraordinary morbidity and mortality every year. Although vector control interventions are among the most effective known ways to prevent the transmission of mosquito-borne diseases, new strategies and paradigms are desperately needed to complement currently available tools. One novel approach to vector control currently being considered is a combined push-pull strategy, which uses spatial repellents and baited traps simultaneously in order to reduce human-vector interactions and to facilitate the capture and removal of vectors from the local environment. Here, a series of interdisciplinary studies was conducted to evaluate the potential for push-pull strategies to control mosquito vectors of human disease and to better define the physiological basis of spatial repellency.
Performance of Sweetpotato Varieties Grown Using Black Plastic Mulch in Pennsylvania

Sweetpotato (Ipomoea batatas) production in Pennsylvania and the northeastern United States has been increasing steadily. The performance of eight commercially available sweetpotato varieties and two unreleased accessions grown on raised beds and covered with black plastic mulch in Pennsylvania was evaluated. All varieties and accessions were evaluated in 2 successive years (2018 and 2019) at Rock Springs, PA. There were statistically significant differences in total marketable yield (TMY), but not in all yield components in both years. ‘Orleans’, ‘Beauregard’, ‘Averre’, and ‘Covington’ consistently produced high marketable yields and suitable U.S No.1 grade storage roots. ‘Bonita’ (tan skin/white flesh) and ‘Carolina Ruby’ [red skin/orange flesh (OF)] produced consistent yields in both years (range, 330–430 bushels/acre; 50-lb bushel). NC413 [purple skin (PS)/purple flesh (PF)] produced the lowest yield in 2018 and was discarded for future trials. In 2019, NCP13-0030 (PS/PF) produced good yields and shapes comparable to OF varieties. Overall total yields (TYs) measured in this study compared satisfactorily with average nationwide yields, with several varieties producing more than 500 bushels/acre.
THE DATAFICATION OF CHILDHOOD: EXAMINING CHILDREN’S AND PARENTS’ DATA PRACTICES, CHILDREN’S RIGHT TO PRIVACY AND PARENTS’ DILEMMAS

Mascheroni, G. , Livingstone, S. , Stoilova, M. , Nandagiri, R. , Milosevic, T. , Zdodrowska A. , Staksrud, E. , Siibak, A. , Sukk, M. , Zaffaroni, L. G. , Cino, D. , & Wartella, E. (2020, October 28-31). The datafication of childhood: examining children’s and parents’ data practices, children’s right to privacy and parents’ dilemmas. Panel presented at AoIR 2020: The 21th Annual Conference of the Association of Internet Researchers. Dublin, Ireland: AoIR. Retrieved from http://spir.aoir. org. THE DATAFICATION OF CHILDHOOD: EXAMINING CHILDREN’S AND PARENTS’ DATA PRACTICES, CHILDREN’S RIGHT TO PRIVACY AND PARENTS’ DILEMMAS
Opposite associations of collective narcissism and in-group satisfaction with intergroup aggression via belief in the hedonistic function of revenge

We investigated whether collective narcissism (i.e., believing that the in-group is exceptional but insufficiently recognized by others) and in-group satisfaction (i.e., believing that the in-group is a source of satisfaction) have opposite, unique associations with intergroup aggression via belief in the hedonistic function of revenge (i.e., an expectation of emotional reward from harming others in response to feeling oneself harmed). Results of two studies conducted in Poland (N = 675) found that collective narcissism is positively related to belief in the hedonistic function of revenge, whereas in-group satisfaction is negatively related, and both are related to intergroup aggression. These relationships were found only when the overlap between collective narcissism and in-group satisfaction was partialled out. The results shed a new light on the mechanisms linking in-group positivity to out-group derogation, and highlight the importance of investigating revenge motivations in the intergroup relations.
Physicians' strategies for using family history data: having the data is not the same as using the data.

Objective To identify needs in a clinical decision support tool development by exploring how primary care providers currently collect and use family health history (FHH). Design Survey questionnaires and semi-structured interviews were administered to a mix of primary and specialty care clinicians within the University of Utah Health system (40 surveys, 12 interviews). Results Three key themes emerged regarding providers' collection and use of FHH: (1) Strategies for collecting FHH vary by level of effort; (2) Documentation practices extend beyond the electronic health record's dedicated FHH module; and (3) Providers desire feedback from genetic services consultation and are uncertain how to refer patients to genetic services. Conclusion Study findings highlight the varying degrees of engagement that providers have with collecting FHH. Improving the integration of FHH into workflow, and providing decision support, as well as links and tools to help providers better utilize genetic counseling may improve patient care.
A molecular‐genetic understanding of diapause in spider mites: current knowledge and future directions

During unfavourable conditions, many arthropods have the ability to enter into diapause and synchronize their development and reproduction to seasonal patterns. Diapause or winter hibernation in insects and mites is set off by a number of cues, with photoperiod being the most well‐defined and strongest signal. This review focuses on the current knowledge of ‘‐omics’ data and the genetics of diapause in the two‐spotted spider mite Tetranychus urticae, a member of the family Tetranychidae (Arthropoda: Chelicerata: Arachnida: Acari). This species is a serious polyphagous pest and females undergo a reproductive facultative diapause when immature stages are exposed to long nights. Winter hibernation induces different physiological processes characterized by a metabolic suppression, different energy use, increased stress tolerance and the production of cryoprotectants, all initiated by a complex signal transduction pathway. Keto‐carotenoids are known to cause the deeply orange colour typical for diapausing females. Furthermore, research with colour mutants of T. urticae has shown the need for carotenoids with respect to the induction of diapause, even though the molecular‐genetic mechanisms underlying these colour phenotypes are still unknown. In addition, marked latitudinal variation in diapause incidence among populations has been observed in nature, with modes of inheritance ranging from recessive to dominant, as well as monogenic to polygenic. We end by highlighting the emerging opportunities for functional studies that aim to unravel the complex factors underlying diapause in spider mites.
A Deep Learning Model for Demand-Driven, Proactive Tasks Management in Pervasive Computing

Pervasive computing applications deal with the intelligence surrounding users that can facilitate their activities. This intelligence is provided in the form of software components incorporated in embedded systems or devices in close distance with end users. One example of infrastructure that can host intelligent pervasive services is the Edge Computing (EC) ecosystem. EC nodes can execute a number of tasks for data collected by devices present in the Internet of Things (IoT). In this paper, we propose an intelligent, proactive tasks management model based on demand. Demand depicts the number of users or applications interested in using the available tasks in EC nodes, thus characterizing their popularity. We rely on a Deep Machine Learning (DML) model and more specifically on a Long Short Term Memory (LSTM) network to learn the distribution of demand indicators for each task and estimate the future interest in them. This information is combined with historical observations of and support for a decision making scheme to conclude which tasks that are offloaded due to limited interest in them. We have to recognise that, in our decision making, we also take into consideration the load that every task may add to the processing node where it will be allocated. The description of our model is accompanied by a large set of experimental simulations for evaluating the proposed mechanism. We provide numerical results and reveal that the proposed scheme is capable of deciding on the fly, while concluding the most efficient decisions.
A scalable synthesis of 2D laminate Li3VO4/C for robust pseudocapacitive Li-ion storage

Li3VO4 is a new insertion type anode material with combined merits of high capacity and safety, demonstrating great potential in Li-ion batteries. However, its practical application is hindered by unscalable fabrication coupled with particular challenges in morphology regulation and unsatisfactory rate capability. Here, a 2D laminate Li3VO4/C anode is first constructed via a concise, low-cost, and environment-friendly biomass-aided approach. Li3VO4/C shows robust pseudocapacitive Li-ion storage, rendering high capacity and excellent rate capability. After 4 periodic rate performance testing from 0.1 to 2.0 A g−1 over 330 cycles, a high reversible capacity of 612.0 mA h g−1 can be reverted. The excellent performance of the 2D laminate Li3VO4/C and the scalable fabrication approach will advance the practical applications of Li3VO4.
High Field MRI in Human African Trypanosomiasis (HAT)

Human African Trypanosomiasis (HAT) or sleeping thickness is a forest and rural disease; where agriculture is the main activity. It is a chronic and lethal disease without treatment. HAT is caused by two parasites; Trypanosoma Brucei Gambiense (gTB) and Trypanosoma Brucei Rhodesiense (rTB) transmitted to humans by the tsetse fly. It is endemic condition in Africa between the 15° north latitude and the 20° south latitude. It is reported outside this area in travelers who stayed in endemic zone. Infection by gTB is wider and more frequent (98%) than that by rTB (2%). The Democratic Republic of Congo is the most affected country with more than 75% of reported cases. The geographical distribution is not homogeneous. There are more affected regions in a zone called “foci” which represents areas favorable to the development of the vector. Its diagnosis and treatment are very important because of its social and economic impact at both the individual and community levels. Promising molecules including fexinidazole are currently undergoing testing. Nowadays populations move more and more easily but the discovery of this disease in daily neuroradiological practice is exceptional. We propose in this paper through two observations, reminders on epidemiological, clinical and MRI features of HAT. It typically performs the edematous, bilateral and diffuse encephalitis. It is important to distinguish these aspects from the arsenic-induced encephalitis that may occur during treatment. Only vector control allows eradicating this disease. WHO has set targets elimination of HAT as a public health problem for 2020 deadline.
Proteome response of wild wheat relative Kengyilia thoroldiana to drought stress

Yang, S. , Li, X. , Ma, Y. , Sun, X. , Yang, Y. and Yang, Y. 2015. Proteome response of wild wheat relative Kengyilia thoroldiana to drought stress. Can. J. Plant Sci. 95: 237-249. Wild relatives of crops provide plant breeders with a broad pool of potentially useful genetic sources. The genus Kengyilia, being a member of the tribe Triticeae, is related to wheat, barley, and other cereals and forage grasses. We studied proteomic changes in K. thoroldiana seedlings in response to drought stress after withholding water for 0, 3, 6, 9 and 15 d. To determine the proteomic changes that occurred in leaves of K. thoroldiana under drought stress, two-dimensional gel electrophoresis (2-DE) and mass spectrometry were performed to identify protein expression changes. Seventy proteins showing reproducible and significant expression changes were identified. Among them, 28 proteins were up-regulated, whereas seven proteins were down-regulated. Based on database-annotated functions, these 70 proteins were categorized as energy metabolism, stress response, antioxidative enzyme, transcript and signal transduction, predicted proteins, and chloroplast-related proteins. Cluster analysis further showed that the up-regulated proteins were mainly stress response proteins and antioxidative enzymes. These results suggest that K. thoroldiana may resist drought stress by increasing the expression of stress response proteins and by producing antioxidative enzymes to remove reactive oxygen species. We conclude that the K. thoroldiana drought stress response mechanism could represent a useful genetic resource for related studies in wheat.
Preparation and Properties of Silver Nanopowders and Composites Based on a Radiation-Chemical Method

Alumina powders coated with silver consisting of nanoparticles with sizes of 50 and 80 nm were produced by a radiation-chemical method. The coating percentage was from 2–3% to 16–40%. Antibacterial properties of the composite have been investigated on wine yeast, Escherichia coli and Staphylococcus aureus bacteria. The photocatalytic properties of the nanopowder were investigated, which showed the potential.
Logging increases the functional and phylogenetic dispersion of understorey plant communities in tropical lowland rain forest

Logging is a major driver of tropical forest degradation, with severe impacts on plant richness and composition. Rarely have these effects been considered in terms of their impact on the functional and phylogenetic diversity of understorey plant communities, despite the direct relevance to community reassembly trajectories. Here, we test the effects of logging on functional traits and evolutionary relatedness, over and above effects that can be explained by changes in species richness alone. We hypothesised that strong environmental filtering will result in more clustered (under‐dispersed) functional and phylogenetic structures within communities as logging intensity increases. We surveyed understorey plant communities at 180 locations across a logging intensity gradient from primary to repeatedly logged tropical lowland rain forest in Sabah, Malaysia. For the 691 recorded plant taxa, we generated a phylogeny to assess plot‐level phylogenetic relatedness. We quantified 10 plant traits known to respond to disturbance and affect ecosystem functioning, and tested the influence of logging on functional and phylogenetic structure. We found no significant effect of forest canopy loss or road configuration on species richness. By contrast, both functional dispersion and phylogenetic dispersion (net relatedness index) showed strong gradients from clustered towards more randomly assembled communities at higher logging intensity, independent of variation in species richness. Moreover, there was a significant nonlinear shift in the trait dispersion relationship above a logging intensity threshold of c. 65% canopy loss (±17% CL). All functional traits showed significant phylogenetic signals, suggesting broad concordance between functional and phylogenetic dispersion, at least below the logging intensity threshold. Synthesis. We found a strong logging signal in the functional and phylogenetic structure of understorey plant communities, over and above species richness, but this effect was opposite to that predicted. Logging increased, rather than decreased, functional and phylogenetic dispersion in understorey plant communities. This effect was particularly pronounced for functional response traits, which directly link disturbance with plant community reassembly. Our study provides novel insights into the way logging affects understorey plant communities in tropical rain forest and highlights the importance of trait‐based approaches to improve our understanding of the broad range of logging‐associated impacts.