Miracle-dz/UniFAR-FTUs huggingface dataset:
Oxytocin: functions and activation

RESUMO O objetivo desta revisão é descobrir a atividade da ocitocina em vários sistemas biológicos do corpo relacionados às funções reprodutivas. A ocitocina é um hormônio peptídico produzido no cérebro, armazenamento e secreção da hipófise na maioria dos animais, especialmente nos mamíferos. A ocitocina foi descoberta pela primeira vez por Henry Dale em 1906. Considerando que sua estrutura foi descoberta em 1952. A ocitocina possui uma ampla variedade de funções fisiológicas, como remoção de leite, comportamento materno, câncer e comportamento sexual nos dois tipos de sexo (masculino e feminino) , por exemplo, desempenha um papel no desempenho da excitação peniana, ejaculação, glândulas acessórias e nas contrações dos músculos lisos do útero e pélvica durante o acasalamento e parto, crescimento e desenvolvimento do nível do corpo lúteo e progesterona no sangue. Além disso, o efeito da ocitocina em alguns hormônios como a prolactina e o hormônio luteinizante. Além disso, existe uma relação entre ocitocina e tolerância ao estresse. Portanto, é importante e necessário entender os efeitos da ocitocina nas funções de alguém para fornecer informações sobre os processos biológicos do corpo que controlam esse hormônio.
Changing Prices in a Changing Climate: Electoral Competition and Fossil Fuel Taxation

When do governments adopt ambitious climate policy? Charting the theoretical territory between climate change politics and long-term policymaking, this paper highlights the role of electoral competition in shaping how politicians respond to the intertemporal tradeoff of one important climate change mitigation policy: fossil fuel taxation. The more secure the government is in office, the more insulated it is from the vagaries of political competition, and the more likely it is to impose costs on constituents today to generate a future stable climate. By influencing governments’ time preferences, competition structures the myopia of elected officials. I test the arguments using an original dataset of gasoline taxation across high-income democracies between 1988 and 2013. I find evidence that higher levels of electoral competition are associated with lower gasoline tax rates, and that the relationship is moderated by the level of costs imposed on voters, but not government partisanship. More generally, the analysis highlights when governments can increase consumer prices to address long-term challenges.
Effect of Cover Crop on Carbon Distribution in Size and Density Separated Soil Aggregates

Increasing soil organic carbon (SOC) stocks in agricultural soils can contribute to stabilizing or even lowering atmospheric greenhouse gas (GHG) concentrations. Cover crop rotation has been shown to increase SOC and provide productivity benefits for agriculture. Here we used a split field design to evaluate the short-term effect of cover crop on SOC distribution and chemistry using a combination of bulk, isotopic, and spectroscopic analyses of size-and density-separated soil aggregates. Macroaggregates (>250 µm) incorporated additional plant material with cover crop as evidenced by more negative δ13C values (−25.4‰ with cover crop compared to −25.1‰ without cover crop) and increased phenolic (plant-like) resonance in carbon NEXAFS spectra. Iron EXAFS data showed that the Fe pool was composed of 17–21% Fe oxide with the remainder a mix of primary and secondary minerals. Comparison of oxalate and dithionite extractions suggests that cover crop may also increase Fe oxide crystallinity, especially in the dense (>2.4 g cm−3) soil fraction. Cover crop δ13C values were more negative across density fractions of bulk soil, indicating the presence of less processed organic carbon. Although no significant difference was observed in bulk SOC on a mass per mass basis between cover and no cover crop fields after one season, isotopic and spectroscopic data reveal enhanced carbon movement between aggregates in cover crop soil.
EMC design of AI products

This paper investigates electromagnetic compatibility (EMC) problems in artificial intelligence (AI) products and summarize corresponding solutions. Concept and theories of EMC are introduced in Section II, analysis of EMC problems in AI products basing on three elements of EMC is given in Section III, solutions are presented in Section IV, and conclusions are given in the final Section.
From Village School to Global Brand: Changing the World through Education

10.56 MB Free download From Village School to Global Brand: Changing the World through Education book PDF, FB2, EPUB and MOBI. Read online From Village School to Global Brand: Changing the World through Education which classified as Other that has 256 pages that contain constructive material with lovely reading experience. Reading online From Village School to Global Brand: Changing the World through Education book will be provide using wonderful book reader and it's might gives you some access to identifying the book content before you download the book.
Effective collaboration methods of school media specialists and classroom teachers

Cynthia Anne O'Reilly EFFECTIVE COLLABORATION METHODS OF SCHOOL MEDIA SPECIALISTS AND CLASSROOM TEACHERS 2005/2006 Dr. Marilyn L. Shontz Master of Arts in School and Public Librarianship The purpose of this investigative study was to determine if student achievement was greater when media specialists and classroom teachers spent more time collaborating. This was accomplished by surveying media specialists and the classroom teachers they collaborated with. Surveys were mailed to media specialists in the Cherry Hill Public School District in Cherry Hill, New Jersey. Those media specialists were asked to present a separate survey to classroom teachers they had collaborated with. Results of the surveys determined that 54% of media specialists and classroom teachers felt that their students achieved higher on lesson assessments when the media specialist and classroom teacher collaborated for less than 15 minutes. When media specialists and classroom teachers collaborated for more than 15 minutes, 87% felt that their students achieved higher on lesson assessments. This concluded that students were more likely to achieve higher on lesson assessments when the media specialists and classroom teachers spent more time collaborating. DEDICATION I want to first thank my husband Eric Rothman, my parents Sue and Dave O'Reilly, and all of my friends, especially Andrea Gleckler, for providing the support system I need to accomplish all of my goals. Without their patience and love I could not be the person I am today. I also want to thank Mrs. Gloria Meekins for believing in me.
The Existence of Designs via Iterative Absorption: Hypergraph 𝐹-designs for Arbitrary 𝐹

We solve the existence problem for F F -designs for arbitrary r r -uniform hypergraphs F F . This implies that given any r r -uniform hypergraph F F , the trivially necessary divisibility conditions are sufficient to guarantee a decomposition of any sufficiently large complete r r -uniform hypergraph into edge-disjoint copies of F F , which answers a question asked e.g. by Keevash. The graph case r = 2 r=2 was proved by Wilson in 1975 and forms one of the cornerstones of design theory. The case when F F is complete corresponds to the existence of block designs, a problem going back to the 19th century, which was recently settled by Keevash. In particular, our argument provides a new proof of the existence of block designs, based on iterative absorption (which employs purely probabilistic and combinatorial methods). Our main result concerns decompositions of hypergraphs whose clique distribution fulfills certain regularity constraints. Our argument allows us to employ a ‘regularity boosting’ process which frequently enables us to satisfy these constraints even if the clique distribution of the original hypergraph does not satisfy them. This enables us to go significantly beyond the setting of quasirandom hypergraphs considered by Keevash. In particular, we obtain a resilience version and a decomposition result for hypergraphs of large minimum degree.
A Quaternion-Based Sliding Mode Observer for Gyro-Bias Estimation and Attitude Reconstruction

Localization accuracy is one of the most important parts of Unmanned Vehicle Systems, Automated Vehicles, Robotics and Navigation. The 6-DOF Inertial Measurement Unit (IMU) is a commonly used device for inertial navigation and is composed of a 3-axis accelerometer and 3-axis gyroscope. The body-fixed IMU measurements are combined with initial values to produce a position and orientation estimate in the inertial frame with every new measurement. However, IMU performance is greatly degraded by bias, scale-factor, non-orthogonality, temperature, and noise. This paper develops a sliding mode observer specifically focused on gyroscope bias estimation to improve gyro measurement results. The work presented here improves the performance of tilt sensors equipped in a commercially available smartphones with accelerometers and gyroscopes. The algorithm uses quaternions to avoid the well-known Euler angle singularities also known as gimbal lock. The observed gyro-bias can be used to reconstruct an improved estimation of the real attitude. A sliding-mode observer was constructed, and A* Matrix stability criterion were used to guarantee observer error convergence in finite time. The algorithm was verified using both a simulated IMU model and experimental tests with a custom designed rotational platform. Simulation tests used a predefined gyros-bias to ensure the algorithm-estimated results converged to the correct value. Simulation results show the observer error quickly converges to zero and the gyro-bias estimation converged to the expected values. The results also show that the proposed method is very effective for reconstructing the real attitude using the observed gyro-bias. This study presents a fast, simple gyro-bias estimation method that can help reconstruct the real attitude with a simple formulation that eliminates complicated constraints.
Host community assembly modifies the relationship between host and parasite richness

Host and parasite richness are generally positively correlated, but the stability of this relationship during community assembly remains untested. The composition of host communities can alter parasite transmission, and the relationship between host and parasite richness is sensitive to parasite transmission. Thus, changes in composition during host community assembly could strengthen or weaken the relationship between host and parasite richness. Host community assembly, in turn, can be driven by many processes, including resource enrichment. To test the hypothesis that host community assembly can alter the relationship between host and parasite richness, we experimentally crossed host diversity and resource supply to hosts, then allowed communities to assemble. As previously shown, initial host diversity and resource supply determined the trajectory of host community assembly, altering post-assembly host species richness, richness-independent host phylogenetic diversity, and colonization by exotic host species. Throughout community assembly, host richness predicted parasite richness. As predicted, this effect was moderated by exotic abundance: communities dominated by exotic species exhibited a stronger positive relationship between post-assembly host and parasite richness. Ultimately, these results suggest that, by modulating parasite transmission, community assembly can modify the relationship between host and parasite richness, providing a novel mechanism to explain contingencies in this relationship.
Neoplastic transformation of p16INK-deficient human fibroblasts by co-operating cellular oncogenes.

A common defensive mechanism used by proliferating cells in response to potentially damaging signals is the induction of cell cycle arrest. The upregulation of the cell cycle inhibitor, plb^^'^^ causes arrest in response to a variety of cellular insults such as environmental stress, oncogenic signalling and telomere loss. Remarkably, the DNA locus on which the INK4a gene is found, CDKN2A, encodes two structurally distinct proteins that are expressed in response to inappropriate proliferative signals, and activate pivotal cell cycle control and tumour suppressor pathways. Thus, p i p r e v e n t s the phosphorylation and functional inactivation of the retinoblastoma protein (Rb) by cyclin dependent kinases, whereas pl4**^ prevents the Mdm2-mediated ubiquitination and degradation of p53. Therefore, this single genomic locus has the capacity to modulate signals to both Rb and p53 the executors of two pivotal checkpoints in the cell division cycle. To gain further insight into the roles of INK4a and ART, the behaviour of primary human dermal fibroblasts from rare, melanoma-prone individuals who have inherited germline mutations in both alleles of pl6^^^"^* has been investigated. These cells are operationally deficient for pl6^^^"^ ̂ but functional for pl4**^. Work presented in this thesis shows that, when immortalized by telomerase, they are resistant to the arrest induced by expression of either ectopic Ras or Myc in wild-type cells, and are able to grow as anchorage-independent colonies in soft agar. However, they do not grow as tumours in nude mice. Cells expressing both Myc and Ras form large colonies and are able to grow as tumours in nude mice. Due to the low penetrance and long latency of these tumours, they have been analysed for additional acquired alterations that may be required for tumorigenesis. Thus, an attempt has been made to establish the minimum number of alterations to cellular genes required to convert a primary human fibroblast into a tumour cell.
İnternet Perakendeciliğinde Elektronik Hizmet Kalitesinin Müşteri Tatmini ve Müşteri Sadakati Üzerindeki Rolü

Son yillarda teknoloji alanindaki gelismeler internetin kullanim alaninin yayginlasmasina ve cesitlilik gostermesine yol acmistir. Bu durum bircok sektorun yani sira perakende sektorunu de etkilemistir. Internetten alisverisin yayginlasmasiyla birlikte perakendeciler fiziksel magazalarinin yani sira bu alanda da faaliyet gostermeye baslamislardir. Internetten alisverisin zaman ve maliyet tasarrufu saglamasi, karsilastirma imkani sunmasi, her saat ulasilabilir olmasi gibi avantajlari tuketicileri internetten alisverise ve cevrimici perakende magazalarini tercih etmeye tesvik etmektedir. Gunumuzde ortaya cikan ve sadece internet uzerinden perakendecilik yapan isletmelerin yani sira kendi isimleriyle ve markalariyla actiklari internet siteleri uzerinden faaliyetlerini yuruten perakendeciler de bulunmaktadir. Artan rekabet ortaminda hem fiziki magazada hem de online ortamda faaliyet gosteren isletmelerin hizmet kaliteleri tuketicilerin memnuniyeti icin onemli olmaya devam etmektedir. Arastirmanin amaci, elektronik perakendecilikte algilanan hizmet kalitesi boyutlarinin e-tatmin ve e-sadakat boyutlari uzerindeki etkilerini belirlemektir. Bu calismada e-perakende sektoru olarak online teknoloji magazalarindan Teknosa, Bimeks, Media Markt tercih edilmistir. Bu amac kapsaminda Istanbul’da yasayan, 18 yasindan buyuk 473 internet kullanicisi uzerinde yuz yuze anket yontemi kullanilmistir. Hipotezlerin testi icin yapisal esitlik modelinden yararlanilmis olup yapilan analizlerde e-perakendecilikte hizmet kalitesi boyutlarindan yalnizca guvenilirlik boyutunun e-tatmin uzerinde pozitif bir etkiye sahip oldugu, tatminin de sadakat uzerindeki etkisinin pozitif oldugu gorulmektedir.
Continuous Spinal Anesthesia for Hemiarthroplasty in a Geriatric Patient with Multiple Co-Morbidities

Elderly patients with co-morbidities have an increased risk of perioperative mortality and morbidity from anaesthesia. Here is a case report of one such patient who underwent hemiarthroplasty under continous spinal anaesthesia. This technique was advantageous over single shot spinal , epidural and general anaesthesia.
Blood Culture From The Umbilical Vein In The Diagnosis Of Neonatal Sepsis.

Background: Sepsis is a significant cause of mortality and morbidity in Neonatology Departments. Frequently neonatologists use the presence of a positive blood culture to confirm diagnosis and then they undergo lumbar puncture. Positive blood cultures are the gold standard and are used to predict neonatal outcome and determine type of antibiotics combination ant length of treatment. Objective: The aim of this study was to obtain blood culture from umbilical vein in newborns with infection risk factors and seeing if its culture is more sensible for isolating micro-organisms. Design: A prospective study of 784 deliveries with 45 infection risk factors newborns Patients: We select a cohort of newborns with perinatal infection risk factors during 3 months. Clinical data for these neonates were recorded prospectively and in the delivery room a blood sample from the umbilical vein was culture. These neonates were followed during almost the firsts 72 hours of live and clinical and laboratory test was made. Results. We obtained a total sample size in this study of 30 blood cultures. From this sample blood culture was positive in 13 (43%) and negative in 17 (57%). Of the 13 positive blood cultures 7 (54%) neonates presents clinical and laboratory findings and sepsis diagnosis was made, 3 (23%) were considered contaminants and 3 (23%) were bacteraemies. In all neonates serial RBC, leukocyte counts and CRP were made and in newborns with positive blood culture a new blood sample for culture and CSF culture was performed. Conclusions: Diagnosis of neonatal sepsis by positive blood culture in clinical practice is difficulted by maternal antibiotic prophylaxis and blood sample size. Various diagnostics approaches are necessary to make diagnosis and to determine the length of therapy. Umbilical vein samples represented a new and more sensible way to diagnostics early neonatal sepsis.
Volunteer Tourism: Motivations of Thai Tourists and Western Tourists

This study examines the motivations of Thai tourists and Western tourists in engaging in a volunteer tourism vacation in Bangkok, Thailand, and analyses how and why the motivations of each group are similar to or different from each other. An interpretive paradigm utilising a qualitative methodological approach was employed. The informants consisted of fourteen Thai tourists and fifteen Western tourists, all of which were selected by convenient sampling and snowball sampling. The findings revealed that there were some common motivations between these tourists including: (i) to gain new experiences; (ii) personal development and growth; and (iii) personal interest in certain volunteer activities. However, it was also found that there were differences in motivations between these groups, including: (i) to gain inner happiness; (ii) to help others; (iii) to learn/be immersed in local culture in a deeper way; (iv) to meet new friends; and (v) to visit Bangkok and Thailand. The first motivation was found only in the group of Thai tourists whereas the rest belonged to only the Western tourists.
Psychiatric Boarding in U.S. EDs: A Multifactorial Problem that Requires Multidisicplinary Solutions

ED visits for psychiatric conditions make up an ever-increasing share of all ED visits. Patients with psychiatric complaints have a significantly greater length-of-stay in the ED than patients with non-psychiatric complaints. Prolonged boarding in the ED for psychiatric patients is associated with lower quality care for psychiatric patients and further contributes to overall ED crowding.
The preventive effect of Nigella sativa seed on gastric ulcer induced by indomethacin in rat

IntroductionNonsteroidal anti-inflammatory drugs (NSAIDs) are considered as one of the most administrated groups of medications worldwide. Due to the role of NSAIDs in inducing gastric ulceration, their clinical applications are still challenging. Nigella sativa seed is widely used as herbal medication against gastrointestinal complications. The present experiment was carried out to investigate the impact of N. sativa seed hydro-alcoholic extract on gastric ulcer induced by indomethacin (IND) and to evaluate its possible mechanisms in rat.MethodsThis study was performed on 48 male Wistar rats. Acute gastric ulceration was induced by IND (35 mg/kg). N. sativa seed extract (100, 200, 400 mg/kg) and ranitidine (50 mg/kg) were administered orally for five days before induction ulcer. Ulcer index, gastric acid secretion, gastric mucus content, glutathione (GSH), malondialdehyde (MDA), total hexose, gastric juice protein content were determined on the fifth day.ResultsThe ulcer index in all groups of N. sativa seed was significantly lower than that of the IND group. N sativa seed considerably decreased MDA and protein content, but increased total thiol, total hexose, and mucus content compared to the IND group. N. sativa seed did not affect gastric acid secretion.ConclusionThese findings were indicative of the gastroprotective effect of N. sativa seed against the IND-induced ulcer, suggesting that it can mainly be exerted through the anti-oxidant activity of the extract as well as its role in stimulating gastric mucus secretion and increasing total hexose in the gastric mucosa.
Changing everyday activities and technology use in mild cognitive impairment

Introduction Knowledge of the conditions under which older adults facing cognitive decline engage in everyday activities is of major importance for occupational therapists in designing supportive interventions. This study aimed to investigate perceived activity involvement over time and its longitudinal relationship to perceived ability to use everyday technology in older adults with mild cognitive impairment. Method Thirty-seven older adults with mild cognitive impairment at inclusion were assessed over 4 years. Overall and item-specific activity involvement were analyzed using mixed-linear-effect modeling and differential item functioning. Furthermore, overall activity involvement and ability in everyday technology use were correlated. Results Overall activity involvement decreased significantly over time. When adjusting for declining ability in the sample, actual differential item functioning indicated descending involvement in seven of 15 activities, while eight activities were stable. All leisure activities descended. The positive correlations between activity involvement and ability in everyday technology use became stronger over time. Conclusion Variations across activities and time-points suggest that occupational therapists should repeatedly monitor the increasingly associated aspects of activity involvement and ability to use everyday technology in persons with cognitive decline.