Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of time on the plant availability of Cd, Ni and Zn after sewage sludge has been applied to soils

A pot experiment was conducted to test the hypothesis that decomposition of organic matter in sewage sludge and the consequent formation of dissolved organic compounds (DOC) would lead to an increase in the bioavailability of the heavy metals. Two Brown Earth soils, one with clayey loam texture (CL) and the other a loamy sand (LS) were mixed with sewage sludge at rates equivalent to 0, 10 and 50 t dry sludge ha - 1 and the pots were sown with ryegrass (Lolium perenne L.). The organic matter content and heavy metal availability assessed with soil extractions with 0.05 M CaCl 2 were monitored over a residual time of two years, while plant uptake over one year, after addition of the sludge. It was found that the concentrations of Cd and Ni in both the ryegrass and the soil extracts increased slightly but significantly during the first year. In most cases, this increase was most evident especially at the higher sludge application rate (50 t ha - 1 ). However, in the second year metal availability reached a plateau. Zinc concentrations in the ryegrass did not show an increase but the CaCl 2 extracts increased during the first year. In contrast, organic matter content decreased rapidly in the first months of the first year and much more slowly in the second (total decrease of 16%). The concentrations of DOC increased significantly in the more organic rich CL soil in the course of two years. The pattern followed by the decomposition of organic matter with time and the production of DOC may provide at least a partial explanation for trend towards increased metal availability.
Definition of the Hydrogen Bond

Department of Inorganic and Physical Chemistry, Indian Institute of 8 Science, Bangalore. 560012, India; Solid State and Structural 9 Chemistry Unit, Indian Institute of Science, Bangalore. 560012, India; 10 30, Kimberley Road, Chesterton, Cambridge, CB4 1HH, UK; 11 Department of Chemistry, Laboratory of Intermolecular Interactions, 12 University of Warsaw, Warsaw, PL-02093, Poland; Department of 13 Chemistry and Biochemistry, 0300 Old Main Hall, Utah State University, 14 Logan, UT. 84322 USA; Juan de la Cierva 3, Instituto de Quimica 15 Medica, Madrid, E-28006, Spain; Department of Physical and 16 Theoretical Chemistry, Oxford University, South Parks Road, Oxford 17 OX1 3QZ, UK; Department of Chemistry, 225 Prospect Street, Yale 18 University, New Haven, CT 06511-8499 USA; Department of 19 Chemistry and Biochemistry, 695, Park Avenue, City University of New 20 York Hunter College, New York, NY 10065 USA; Institute of Organic 21 and Biochemistry, Academy of Sciences of Czech Republic, 22 Flemingovo nám 2 Praha CZ 16610 Czech Republic; Department of 23 Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 24 Copenhagen Ø, Denmark; School of Chemistry, University of Bristol, 25 Bristol BS8 1TS United Kingdom; Department of Chemistry, 26 University of Pisa, Via Risorgimento 35 Pisa 1-56125 Italy; 27 Department of Chemistry and Biochemistry, University of Colorado, 28 Boulder, CO80309 USA. 29
Bioavailability and biological effects of the isoflavone glycitein and isoflavone glucuronides: role of glucuronide in human natural killer cell modulation in vitro

Lower incidence of breast cancer in Asia has been connected to the higher intake of isoflavone-containing soy foods. The effort to study soy isoflavones as health protective compounds has come to some positive results, like their effects in cancer prevention. lowering blood cholesterol level and osteoporosis prevention. In order to characterize the bioavailability of the third major isoflavone glycitein and to assess its potential healthprotective effects, a comparison study with other isoflavones was conducted in humans with moderate fecal isoflavone degradation activity. The average 48 h urinary excretions of daidzein, glycitein and genistein were 50, 45 and 35% of the total dose ingested, respectively, at which daidzein and glycitein were not different from each other but they were significantly greater than genistein {p = 0.01). Plasma isoflavone concentrations paralleled relative amounts of isoflavones in soymilk at 6 and 24 h but not in soygerm in women at 6 h. To characterize soy isoflavone metabolism, three feeding protocols were conducted in women. By using selective hydrolysis enzymes, the distribution of glucuronide and aglycone isoflavones in both urine and plasma were obtained. At 3 h after soymilk intake, 59.4% of total daidzein and 50.9% of total genistein appeared in plasma as glucuronides. About 76.8% of total daidzein and 70.9% of total genistein presented in urine (24 h) were glucuronides. Significantly higher percentages of aglycone appeared in plasma than in urine. A steady state was observed with sbc consecutive days feeding. As the major metabolite of isoflavone, the glucuronide forms might contribute to observed effects of soy isoflavones. The major metabolites of daidzein and genistein glucuronides were assayed for their ability to modulate human natural killer (NK) cells and NK3.3 cell line alone or in
Towards the Open Ontology for IoT Ecosystem’s Security

The IoT ecosystem is complex and includes hardware devices, services, software, connectivity, standards and protocols. IoT is continuously and persistently contributing to the ubiquity of technology in all aspects of human endeavours, and trends seem to indicate that myriad of IoT solutions are developed and/or bought for various purposes, from the personal home to industrial usages, with the alarming lack of security concerns, giving priority mostly to the fast and cost-effective development. Given the complex nature of such solutions, it is rarely seen that the security aspect is considered through all of the IoT ecosystem elements; also, one of the significant reasons being that the IoT solutions are not always developed in a holistic nature, within the same company, but only provide parts of the complete IoT solution. In order to enable easier and more secure development of IoT solutions, this paper presents first steps towards developing the open ontology for IoT ecosystem elements security, relating them with existing security concepts, primitives, threats, vulnerabilities and practices.
Exploration of Influential Determinants for the Adoption of Business Intelligence System in the Textile and Apparel Industry

The textile and apparel industry is prone to digitization with business intelligence systems (BIS) and big data concepts to contribute the global sustainability. BIS, an impactful and leading technology, is being implemented in many industrial sectors but almost 80% of BIS fail to give expected results due to unknown reasons. Although many scholars put effort into finding the influential determinants for the BIS implementation, they neglect the BIS adoption context, especially in the textile and apparel industry. A purposive and proportionate choice of potential determinants in the context of adoption would contribute significantly to the success of BIS. Multi-stage research is employed to identify and prioritize the significant determinants. In the first stage, twenty-two semi-structured in-depth interviews are conducted with seventeen textile and apparel companies. Ten significant determinants emerged after thematic analysis of interview data. The determinants are sustainability, competitive pressure, market trends, compatibility, technology maturity, leadership commitment and support, satisfaction with existing systems, sustainable data quality and integrity, users’ traits, and interpersonal communications that influence the adoption of BIS. In the second stage, the Best Worst Method (BWM) is used to calculate the weights for prioritizing the determinants based on experts’ opinion. These weights are then used to evaluate and rank the determinants. The findings of this research show that the leadership commitment and support, sustainability, users’ traits, and technology maturity, are the top-ranked determinants that influence the practitioners’ choice to adopt the BIS in the textile and apparel industry. The results of this study enable the BIS stakeholders to holistically comprehend the significant determinants that would drive or impede the success of BIS projects in the sustainable textile and apparel industry.
Automated Missed Pay Zones Detection Method Based on BV10 Member Data of Samotlorskoe Field

Automated pay zone detection on well log data using machine learning Nowadays in the oil and gas industry more and more tasks are related to the analysis of big volume of data. Successful solutions to this type of problem are based on machine learning algorithms. The aim of this study is to create an automated model for predicting pay zones based on the analysis of well log data. The object of research are sedimentary deposits of the BV10 object of the Samotlorskoe oil and gas condensate field. In this project an approach for the gradual interpretation of lithotypes, prediction of the saturation type for potential reservoirs and also the prediction of porosity and permeability was chosen. The article discusses the application of three machine-learning algorithms: the support vector machine method, the neural network and the random forest algorithm. The existing problems of the studied data are described as well as methods for solving them and the stages of data preparation. As a result of the analysis it was decided to use a neural network to create a model for predicting pay intervals. Additionally, the accuracy of the model predictions was estimated from two wells excluded from the analysis.
Enfoque del anciano frágil con estenosis aórtica severa

La estenosis aórtica es la valvulopatía más común, su prevalencia aumenta de forma marcada con la edad y representa una importante causa de morbilidad y mortalidad en el anciano. Por tal motivo se ha implementado un nuevo procedimiento llamado: técnica de implantación valvular aórtica transcatéter (TAVI), que ha mostrado resultados superiores a la terapia médica en pacientes no aptos para la cirugía. El TAVI es el procedimiento preferido en pacientes con estenosis aórtica severa (EAS) que presentan alto riesgo de morbimortalidad, en los que una cirugía tradicional implica alto riesgo o que son etiquetados como inoperables. Este procedimiento a pesar de los beneficios que conlleva a los pacientes, puede generar complicaciones, principalmente acceso vascular, accidentes cerebrovasculares secundarios al procedimiento e insuficiencia aórtica post implante. La fragilidad en el anciano representa del 7 al 20% aproximadamente; este factor de riesgo resulta importante pues se ha asociado con el aumento de morbilidad y mortalidad en pacientes que han sido sometidos a TAVI.
Application de Bacillus spp. mésophile dans la lutte biologique

The control of phytopathogenic microorganisms by pesticides has disadvantages for humans and the environment, to which is added the risk of the appearance of new resistant pathotypes. Some microorganisms can serve as excellent biological control agents against cryptogamic diseases. The aim of our work was to isolate strains of phytopathogenic fungi from a large number of diseased plants and to test the antagonistic potency of a mésophilic Bacillus strain in the framework of biological. Among 23 samples of diseased plants, 12 strains of Aspergillus, 10 strains of Penicillium, 2 strains of Fusarium and 2 strains of Alternaria could be isolated. The dominance of the genera Aspergillus and Penicillium may be due to the great dissemination and competitive power over other fungi. The study of the antagonistic potency of the mésophilic bacillus in vitro was based on its ability to inhibit mycelial growth of phytopathogenic fungi. The best antifungal activity is that of mésophilic Bacillus on Penicillium (70%). The use of the mésophilic bacillus also reduced the growth of Aspergillus and Fusarium, inhibition rates were 60% and 33%, respectively. The mésophilic Bacillus strain is interesting, it can be used as a good biological control agent.
Identification of novel microRNAs in rice (Oryza sativa) based on the cleavage signals in precursors

Abstract MicroRNAs (miRNAs) are crucial regulators of gene expression in plants and a growing number of novel miRNA genes have been cloned in rice in recent years. However, there is no evidence that all miRNAs have been discovered, especially for those low expression ones which are difficult to be found by conventional methods. By taking advantage of the finding that DCL1-mediated cleavage signals for the processing of the miRNA precursors could be used as the clues for novel miRNAs’ discovery, a genome-wide search for rice miRNA candidates was carried out. As a result, 51 previously validated miRNAs and 24 novel miRNA candidates were discovered. After target prediction and degradome sequencing data-based validation, coupled with reverse approach retest, 10 miRNA candidate–mRNA target pairs were further identified, providing a basis for in-depth functional analysis of these miRNA candidates. Besides, some isomiRs found in this study showed more likely to be the real miRNAs. We also found an exceptional example which did not obey the rule that 22-nt miRNAs have the ability to trigger the phased siRNAs production from the cleaved targets.
Exploring the Association Between Nutrition and Mental Health in Adolescence: A Systematic Literature Review

Introduction: Throughout life, proper nutrition is important to the brain as it affects cognition and intellectual development. Studies have shown that a lack of certain nutrients can affect the body’s ability to perform mentally and physically. Annually, 14% of children in the United States receive mental health illness diagnoses. However, the link between nutrition and mental health is not clear. The purpose of this systematic literature review on mental health and nutrition in adolescence is to identify any gaps that require future research efforts. Methods: The Elton Bryson Stephens Company ( EBSCO), ProQuest, and Journal Storage (JSTOR) databases were used to search the following terms: nutrition, diet, and mental health. All search results that were published in English between 2014 -2019, conducted in the United States, peerreviewed, and contained subjects 13 to 18-years old were included. Results: A total of 217 articles were identified. After the removal of duplicates and eligibility screening, only two satisfied the criteria. The reports were published in two separate journals during 2018 (n=1) and 2014 (n=1). These quantitative studies used a cross-sectional design with a survey. Common findings across the two studies are (1) nutrition knowledge and frequent family meals are positively associated with the individual social and emotional wellbeing; and (2) poor nutrition can lead to increased bullying among adolescents. Conclusion: The findings from this study suggest that nutrition and mental health in adolescents is not well research. Future research studies are needed to address mental health and nutrition among adolescents.
Social isolation-induced epigenetic and transcriptional changes in Drosophila dopaminergic neurons

Epigenetic mechanisms play fundamental roles in brain function and behavior and stressors such as social isolation can alter animal behavior via epigenetic mechanisms. However, due to cellular heterogeneity, identifying cell-type-specific epigenetic changes in the brain is challenging. Here we report first use of a modified INTACT method in behavioral epigenetics of Drosophila: a method we call mini-INTACT. Using ChIP-seq on mini-INTACT purified dopaminergic nuclei, we identified epigenetic signatures in socially-isolated and socially-enriched Drosophila males. Social experience altered the epigenetic landscape in clusters of genes involved in transcription and neural function. Some of these alterations were predicted by expression changes of four transcription factors and the prevalence of their binding sites in several clusters. These transcription factors were previously identified as activity-regulated genes and their knockdown in dopaminergic neurons reduced the effects of social experience on sleep. Our work enables the use of Drosophila as a model for cell-type-specific behavioral epigenetics.
UNA REVISIÓN SISTEMÁTICA DE LA EFECTIVIDAD Y EFICACIA DE LA TERAPIA DE INTERACCIÓN PADRES-HIJOS

Se ha realizado una revisión sistemática de la efectividad y eficacia de la PCIT a través de estas bases de datos: Scopus, Web of Science, Psyclit, Google Scholar, ResearchGate, Dialnet, y las de la propia terapia. Se han revisado 165 estudios experimentales seleccionados de un total de 225. Para establecer la eficacia de la terapia se han usado los criterios propuestos por la Society of Clinical Child and Adolescent Psychology. Los resultados de esta revisión indican que PCIT es un tratamiento bien establecido para cinco problemáticas infantiles: problemas de conducta, Trastorno Negativista Desafiante, Trastorno por Déficit de Atención con Hiperactividad, prevención del maltrato y para el tratamiento del maltrato infantil. Palabras Parent-Child Interaction Therapy (PCIT) is a brief therapy to effectively treat behavioral problems in children aged 2 to 7. A systematic review of the effectiveness and efficacy of Parent-Child Interaction Therapy (PCIT) has been carried out through these databases: Scopus, Web of Science, Psyclit, Google Scholar, ResearchGate, Dialnet, and those of the therapy itself. From a total of 225 studies, 165 experimental studies were selected and reviewed. The criteria proposed by the Society of Clinical Child and Adolescent Psychology have been used to establish the efficacy of the therapy. The results of this review indicate that PCIT is a well-established treatment for five problems in childhood: behavioral problems, oppositional defiant disorder, attention disorder, prevention of child maltreatment, and child maltreatment.
Über die Geschwindigkeitskonstante von Austauschreaktionen

Es wird zunachst versucht, die Annahme von London ZU begrunden, dass die chemischen Austauschreaktionen adiabatisch verlaufen. Die wesentliche Bedingung hierfur scheint es zu sein, dass die unterste Energieflache energetisch weit getrennt von den ubrigen liegen soll. Ferner wird fur die Umsetzung von Parawasserstoff in normalem Wasserstoff, fur die Eyring und Polanyi die Aktivierungswarme berechnet haben, die absolute Grosse der Geschwindigkeitskonstante bestimmt.
Examining the Diversity of Digenean Trematodes in Blacketts Lake Using Molecular Techniques and Phylogenetic Analysis

Digenean trematodes are parasitic flatworms with complex lifecycles involving multiple larval stages and a minimum of two hosts. The first intermediate host is most commonly a snail, where the parasite replicates asexually, passes through several larval stages and increases in number, before emerging as free-swimming cercarial larvae. Adult parasites can be found in a wide variety of definitive hosts including birds, frogs, and beavers, spanning myriad environments and geographic ranges. Despite the diversity of final hosts, snails remain as bottlenecks in the lifecycles of digenean trematodes. Hence, snails can be used to sample the local diversity of trematodes as a first step in assessing the roles of these parasites in freshwater ecosystems. The larval and adult stages of trematodes are morphologically discrete and span different spatial distributions. Molecular techniques, such as DNA barcoding using the Cytochrome Oxidase subunit I (COI) gene, can be powerful tools for identifying parasite species, determining species richness, and connecting discrete life-history stages spanning different hosts and environments. Here, I have used a DNA barcoding approach to explore species richness and determine species identity (where possible) within two of 13 cercarial morphotypes collected from Blacketts Lake over a 6 year period. COI sequences generated were used in BLAST searches to identify close/identical matches in GenBank, and in phylogenetic analyses to search for closely-related species/genera. BLAST searches showed strong nucleotide matches between morphotype A samples and sequences from the families Strigeidae and Diplostomidae, and between morphotype D samples and sequences from the family Echinostomatidae. Some samples also matched closely with specific parasite species, such as Echinostoma trivolvis and Diplostomum baeri. I also used the percent of nucleotide
3D Chromatin Architecture Remodeling during Human Cardiomyocyte Differentiation Reveals A Role Of HERV-H In Demarcating Chromatin Domains

Dynamic restructuring of chromatin architecture has been implicated in cell-type specific gene regulatory programs; yet, how chromatin remodels during lineage specification remains to be elucidated. Through interrogating chromatin reorganization during human cardiomyocyte differentiation, we uncover dynamic chromatin interactions between genes and distal regulatory elements harboring noncoding variants associated with adult and congenital heart diseases. Unexpectedly, we also discover a new class of human pluripotent stem cell (PSC)-specific topologically associating domains (TAD) that are created by the actively transcribed endogenous retrotransposon HERV-H. Deletion or silencing of specific HERV-H elements eliminates corresponding TAD boundaries, while de novo insertion of HERV-H can introduce new chromatin domain boundaries in human PSCs. Furthermore, comparative analysis of chromatin architecture in other species that lack HERV-H sequences supports a role for actively transcribed HERV-H in demarcating human PSC-specific TADs. The biological role of HERV-H is further underscored by the observation that deletion of a specific HERV-H reduces transcription of genes upstream and facilitates cell differentiation. Overall, our results highlight a previously unrecognized role for retrotransposons in restructuring genome architecture in the human genome and delineate dynamic gene regulatory networks during cardiomyocyte development that inform how non-coding genetic variants contribute to human heart diseases.
Firm specific determinants of capital structure in European advanced developing countries

The problem of the determinants of the firm financing structure has been researched in literature for years. Still, there is a lot of ambiguity and difference of opinion in that area. Consequently, in this study the authors have decided to analyse firm specific determinants of capital structure in selected advanced developing economies. The research was conducted on companies from four European markets: Polish, Czech, Greek, and Hungarian. The analysed data covered the period 2009–2017. The applied research method was panel data regression with fixed effects. The outcome shows that company decisions concerning the source of financing from the Greek and Hungarian markets are better explained by the pecking order theory, while in the case of the Czech market the trade-off theory works better. For the Polish market neither the pecking order theory nor the trade-off theory has been proved convincingly.
The Mitochondrial Genome and PhylogeneticRelationships of Muong Lay Black Pig (Sus scrofa)in Vietnam

Muong Lay black pig is an indigenous breed of livestock and has recently been listed for conservation in Vietnam. The aim of this study was to investigate the phylogenetic relationship of the Muong Lay black pig with other pig breeds by sequencing its mitochondrial genome (mtDNA). The PCR products were sequenced by Applied Biosystems 3500 Genetic Analyzer. The complete mtDNA sequence was 16,742bp in length and includes two rRNA (12S and 16S), 22 tRNA, 13 mRNA genes, and one control region (D-loop). The phylogenetic analysis was performed by comparing both complete mtDNA and D-loop sequences of Asian and European pig breeds. The results of phylogeny reconstruction revealed that Muong Lay black pig belonged to an Asian clade and clustered with Bihu and Banmei pig from Yangtze River Region and Yellow River Region, while reporting distinctly different phylogenetic relationships with the European breeds.