Miracle-dz/UniFAR-FTUs huggingface dataset:
Measuring Scientific Impact Beyond Citation Counts

The measurement of scientific progress remains a significant challenge exasperated by the use of multiple different types of metrics that are often incorrectly used, overused, or even explicitly abused. Several metrics such as h-index or journal impact factor (JIF) are often used as a means to assess whether an author, article, or journal creates an "impact" on science. Unfortunately, external forces can be used to manipulate these metrics thereby diluting the value of their intended, original purpose. This work highlights these issues and the need to more clearly define "impact" as well as emphasize the need for better metrics that leverage full content analysis of publications.
Vibrio anguillarum: influence of temperature, pH, NaCl concentration and incubation time on growth.

An analysis of the effect of growth conditions on the growth (O.D. values) of five Vibrio anguillarum strains showed that the optima were as follows: pH 7, temperature 25 degrees C, NaCl concentration 2%, and O.D. estimates increased with the incubation time. The independent parameters, as well as their interactions significantly influenced the growth of Vibrio anguillarum (P less than 0.0001). Only the strain-salinity interaction was not always statistically significant. A restriction of the parameters to a level relevant for Danish marine recipients showed that pH and NaCl concentration (salinity) might be of minor importance while the temperature was always of high significance. The possible impact of these observations on local conditions is discussed.
Variations in postoperative and postdischarge wound infection after abdominal hysterectomy

Health care–associated infections (HAIs) are the type of infections that patients acquire while receiving health care treatment at a medical facility including inpatient and outpatient care. It is estimated that one out of every 25 patients who are hospitalized in United States has acquired HAI. In other words, annually 650 000 patients have been diagnosed with HAI. The most common HAI is the surgical site infection (SSI). Thirty‐one percent of hospitalized individuals are diagnosed with surgical site infections (SSIs). According to CDC (2016), in 2011, about 157 500 SSIs were related to inpatient surgeries. On August 18, 2011, the Center for Medicare and Medicaid Services (CMS) announced all SSIs should be reported to the CDC's National Healthcare Safety Network (NHSN) in the CMS Hospital Inpatient Quality Reporting (IQR) Program requirements for 2012. The rule of reporting inpatient data starting from January 1, 2012, particularly emphasized abdominal hysterectomy and colon procedures. SSI is a major public health problem that is increasing morbidity and mortality after a surgical procedure. Every year, approximately 500 000 to 750 000 cases of SSIs occur in the United States. Between 2% and 14% of SSI cases are diagnosed after the patient is discharged from the hospital. Nearly 4% to 25% of patients are readmitted, and some require another surgery due to initial surgical complications, which increase the length of stay at the hospital. Patient readmission due to SSI costs health care industries about $3000 to $29 000 per case and a total of $10 billion per year. Abdominal hysterectomy is considered to be the highest volume surgery in the United States with SSIs increasing morbidity incidence rates by 15% to 25%. The design of this study was a cross‐sectional retrospective analysis of archival data. The purpose of the study was threefold: (1) to evaluate the overall rate of abdominal hysterectomy surgical site infection following postoperative procedures, (2) to distinguish relationship between academic institution, hospital ownership, number of beds, and SSI rates, and (3) to examine the correlation between surgical site infection rate for the hospital and the region (Northeast, Midwest, South, and West). Surgical site infection is an infection which develops within a specific part of the body where the procedure was performed. CDC reports that approximately 1 to 3 out of every 100 patients undergoing
A feature selection analysis in breast cancer diagnosis

In this paper, it is aimed to design a computer aided diagnosis system for breast cancer diagnosis and a mamogram dataset prepared during the Image Retrieval in Medical Applications (IRMA) project is used for the verification of the system. In accordance with this purpose, feature extraction is realized using Local Configuration Pattern algorithm on the pre-processed mamogram images by histogram equalization followed by Non-Local Means Filtering. In addition to these features, vector space is extended by some statistical and frequency-domain features. Besides, feature selection is performed by applying Sequential Forward Feature Selection (SFS) algorithm on the obtained features. Finally, selected features are classified in a 2-stage scheme into 3 different categories (normal, benign, malignant) using linear discriminant classifier, Fisher's linear discriminant analysis, logistic linear classifier, k-nearest neighbor classifier, Naïve Bayes and decision tree classifiers. The results attained at the cases, in which feature selection is performed and not, are compared and it is concluded with approximately 88 % maximum success rate is accomplished in both cases. This success rate is achieved using logistic linear classifier when 15 features are selected among 108 features via SFS algorithm. Analyzing the success performance of all classifiers in both cases, appropriateness of feature selection is decided by means of data storage, memory occupation, and computational time.
Gene-Eden-VIR Is Antiviral: Results of a Post Marketing Clinical Study

Introduction: This paper reports the results of a post marketing clinical study that tested the antiviral properties of Gene-Eden-VIR TM . Specifically, the clinical study tested the effect of Gene-Eden-VIR on the severity, duration, and frequency of symptoms reported by individuals infected with various viruses. The viruses included the Human Papillomavirus (HPV), Herpes Simplex Virus (HSV), Epstein Barr Virus (EBV), Human Cytomegalovirus (HCMV) and Hepatitis C Virus (HCV). The symptoms included abnormal Pap smear, low and high grade cervical dysplasia, warts, blisters, cold sores, hives, skin tabs, panic attacks, depression, kidney problems, sleeping problems, liver problems, fever, fatigue, sore throat, swollen lymph nodes, diarrhea, and weight loss. Treatment: A capsule of Gene-Eden-VIR includes five natural ingredients: 100 mg of quercetin, 150 mg of green tea extract, 50 mg of a cinnamon extract, 25 mg of a licorice extract, and 100 mcg of selenium. The dosage was 1, 2, 3, or 4 capsules per day. The duration of treatment was 2 to 54 weeks. Population: The study population consisted of 60 infected individuals, ages 20 to 66. Results: The participants reported no side effects after taking Gene-Eden-VIR. Seventy three percent of the individuals treated with Gene-Eden-VIR reported a decrease in their symptoms. Specifically, they reported a decrease in the severity (p = 0.006, n = 45), duration (p = 0.009, n = 34), and frequency of their symptoms (p < 0.001, n = 31). Following treatment, the participants also reported an increase in their physical abilities (p < 0.001, n = 47), energy levels (p < 0.001, n = 54), mental abilities (p < 0.001, n = 44), and general health (p < 0.001, n = 46). The results showed that Gene-Eden-VIR has a duration effect (p = 0.044, n = 32), that is, those treated for a longer time reported a larger decrease in their symptoms. The results showed no interviewer bias, no selection bias, and a surprising response shift. The results also showed that Gene-Eden-VIR has therapeutic consistency under varying manufacturing conditions. Conclusions: This post marketing clinical study showed that Gene-Eden-VIR is a safe and effective antiviral treatment. Specifically, the clinical study showed that Gene-Eden-VIR is a safe and effective treatment against the Human Papillomavirus (HPV), Herpes Simplex Virus (HSV), Epstein Barr Virus (EBV), Human Cytomegalovirus (HCMV), and Hepatitis C Virus (HCV). Therefore, health care practitioners should recommend Gene-Eden-VIR as a safe and effective antiviral treatment against these viruses.
Changes in the Plasma Proteome of Manduca sexta Larvae in Relation to the Transcriptome Variations after an Immune Challenge: Evidence for High Molecular Weight Immune Complex Formation*

Manduca sexta is a lepidopteran model widely used to study insect physiological processes, including innate immunity. In this study, we explored the proteomes of cell-free hemolymph from larvae injected with a sterile buffer (C for control) or a mixture of bacteria (I for induced). Of the 654 proteins identified, 70 showed 1.67 to >200-fold abundance increases after the immune challenge; 51 decreased to 0–60% of the control levels. While there was no strong parallel between plasma protein levels and their transcript levels in hemocytes or fat body, the mRNA level changes (i.e. I/C ratios of normalized read numbers) in the tissues concurred with their protein level changes (i.e. I/C ratios of normalized spectral counts) with correlation coefficients of 0.44 and 0.57, respectively. Better correlations support that fat body contributes a more significant portion of the plasma proteins involved in various aspects of innate immunity. Consistently, ratios of mRNA and protein levels were better correlated for immunity-related proteins than unrelated ones. There is a set of proteins whose apparent molecular masses differ considerably from the calculated Mr's, suggestive of posttranslational modifications. In addition, some low Mr proteins were detected in the range of 80 to >300 kDa on a reducing SDS-polyacrylamide gel, indicating the existence of high Mr covalent complexes. We identified 30 serine proteases and their homologs, 11 of which are known members of an extracellular immune signaling network. Along with our quantitative transcriptome data, the protein identification, inducibility, and association provide leads toward a focused exploration of humoral immunity in M. sexta.
Thermobaric control of gravitational potential energy generation by diapycnal mixing in the deep ocean

Sources and sinks of gravitational potential energy (GPE) play a rate‐limiting role in the large‐scale ocean circulation. A key source is turbulent diapycnal mixing, whereby irreversible mixing across isoneutral surfaces is enhanced by turbulent straining of these surfaces. This has motivated international observational efforts to map diapycnal mixing in the global ocean. However, in order to accurately relate the GPE supplied to the large‐scale circulation by diapycnal mixing to the mixing energy source, it is first necessary to determine the ratio, ξ, of the GPE generation rate to the available potential energy dissipation rate associated with turbulent mixing. Here the link between GPE and hydrostatic pressure is used to derive the GPE budget for a compressible ocean with a nonlinear equation of state. The role of diapycnal mixing is isolated and from this a global climatological distribution of ξ is calculated. It is shown that, for a given source of mixing energy, typically three times as much GPE is generated if the mixing takes place in bottom waters rather than in the pycnocline. This is due to GPE destruction by cabbelling in the pycnocline, as opposed to thermobaric enhancement of GPE generation by diapycnal mixing in the deep ocean.
Proton Magnetic Resonance Spectroscopy as a Probe into the Pathophysiology of Autism Spectrum Disorders (ASD): A Review

Proton magnetic resonance spectroscopy (1H‐MRS) is a safe, noninvasive way of quantifying in vivo biochemical and metabolite concentration levels in individuals with Autism Spectrum Disorders (ASD). Findings to date suggest ASD is associated with widespread reduction in N‐acetylaspartate (NAA), creatine plus phosphocreatine (Cr), choline‐containing compounds (Cho), myo‐inositol (mI), and glutamate plus glutamine plus gamma‐Aminobutyric Acid (Glx); however, variable findings, and even substantial increases, are not uncommon depending on the study and/or region‐of‐interest. Widespread reduction of NAA, Cr, Cho, mI, and Glx in ASD likely reflects impaired neuronal function and/or metabolism related to abnormal neurodevelopmental processes. Future studies should attempt to relate 1H‐MRS findings to histological findings and control for variability in subject age and functioning level; this would assist in evaluating the relationship between 1H‐MRS metabolic levels and neuronal and glial cell densities, as well as neurodevelopmental process associated with ASD. Furthermore, more longitudinal 1H‐MRS studies are needed in both control and ASD subjects to attempt to standardize metabolite levels across different developmental periods in well‐defined endophenotypes. This will provide for a standard rubric for which metabolic aberrations (as well as treatment responses) can be measured. With higher magnetic field strengths and spectral‐editing techniques capable of quantifying less‐concentrated metabolites, 1H‐MRS will continue to be an important tool in ASD research. Autism Res 2013, 6: 119–133. © 2013 International Society for Autism Research, Wiley Periodicals, Inc.
3-Gb/s data transmission with GaAs VCSELs over PCB integrated polymer waveguides

GaAs quantum-well (QW)-based vertical-cavity surface-emitting lasers (VCSELs) at 855-nm emission wavelength are investigated for intraboard polymer waveguide links. We report a 3-Gb/s pseudorandom bit sequence (PRES) nonreturn-to-zero (NRZ) data transmission over about 5-cm long printed circuit board (PCB) integrated multinode polymer waveguide arrays of two different geometries at bit-error rates (BERs) of less than 10/sup -11/.
Biological Nitrification Inhibition (BNI): Phenotyping of a Core Germplasm Collection of the Tropical Forage Grass Megathyrsus maximus Under Greenhouse Conditions

Modern intensively managed pastures that receive large external nitrogen (N) inputs account for high N losses in form of nitrate (NO3–) leaching and emissions of the potent greenhouse gas nitrous oxide (N2O). The natural plant capacity to shape the soil N cycle through exudation of organic compounds can be exploited to favor N retention without affecting productivity. In this study, we estimated the relationship between biological nitrification inhibition (BNI), N2O emissions and plant productivity for 119 germplasm accessions of Guineagrass (Megathyrsus maximus), an important tropical forage crop for livestock production. This relation was tested in a greenhouse experiment measuring BNI as (i) rates of soil nitrification; (ii) abundance of ammonia-oxidizing bacteria (AOB) and archaea (AOA); and (iii) the capacity of root tissue extracts to inhibit nitrification in vitro. We then measured N2O emissions, aboveground biomass and forage nutrition quality parameters. Reductions on nitrification activity ranging between 30 and 70% were found across the germplasm collection of M. maximus. Accessions with low nitrification rates showed a lower abundance of AOB as well as a reduction in N2O emissions compared to accessions of high nitrification rates. The BNI capacity was not correlated to N uptake of plants, suggesting that there may be intraspecific variation in the exploitation of different N sources in this grass species. A group of accessions (cluster) with the most desirable agronomic and environmental traits among the collection was identified for further field validation. These results provide evidence of the ability of M. maximus to suppress soil nitrification and N2O emissions and their relationship with productivity and forage quality, pointing a way to develop N conservative improved forage grasses for tropical livestock production.
The Long-Term Outcomes of Refugees: Tracking the Progress of the East African Asians

Refugees are often perceived as an economic ‘burden’, as the current debate on the European refugee crisis illustrates. But there is little quantitative evidence on the medium-term outcomes of refugees in the UK. We fill this gap by looking at the case of ‘East African Asians’ who arrived as refugees in the late 1960s and early 1970s. We discuss from a theoretical and empirical perspective the possible factors that might influence—positively and negatively—their long-term economic outcomes and use data from the UK Census to describe those outcomes 40 years later. We show that their outcomes are at least as good as the population average, with the younger cohort performing better, and better than for economic migrants of the same ethnicity. At least for this group, refugee status, as distinct from ethnicity or immigrant status, appears to have been positively associated with their economic outcomes.
Lactation Reduces Glial Activation Induced by Excitotoxicity in the Rat Hippocampus

Motherhood induces a series of adaptations in the physiology of the female, including an increase of maternal brain plasticity and a reduction of cell damage in the hippocampus caused by kainic acid (KA) excitotoxicity. We analysed the role of lactation in glial activation in the hippocampal fields of virgin and lactating rats after i.c. v. application of 100 ng of KA. Immunohistochemical analysis for glial fibrillary acidic protein (GFAP) and ionised calcium binding adaptor molecule 1 (Iba‐1), which are markers for astrocytes and microglial cell‐surface proteins, respectively, revealed differential cellular responses to KA in lactating and virgin rats. A significant astrocyte and microglial response in hippocampal areas of virgin rats was observed 24 h and 72 h after KA. By contrast, no increase in either GFAP‐ or Iba‐1‐positive cells was observed in response to KA in the hippocampus of lactating rats. Western blot analysis of GFAP showed an initial decrease at 24 h after KA treatment, with an increase at 72 h in the whole hippocampus of virgin but not of lactating rats. The number of GFAP‐positive cells was increased by lactation in the dentate gyrus of the hippocampus but not in CA1 and CA3 areas. The present results indicate that lactating rats exhibit diminished responses of astrocyte and microglial cells in the hippocampus to damage induced by KA, supporting the notion that the maternal hippocampus is resistant to excitotoxic insults.
Design of Self-Sampling Based ASK Demodulator for Implantable Microsystem

In most of bioimplantable or wireless sensor network systems, ASK is one of the most commonly used schemes to modulate the baseband signal with reference to the intermediate or even the carrier frequency. In this study, a novel demodulator architecture is proposed. It is based on a simple self-sampling scheme which is a truly low-cost high-efficiency implementation and has excellent ability to work on a very small difference (0.15 V) between the two modulated levels, which represent the binary '0' and '1' separately. The results show the presented type can be designed to fit the operation carrier for the special need and has a quite area efficiency than the ever published similar works due to its existent digital benefit. In addition, a comforting robustness is also demonstrated under different process variations. According to the merits mentioned above, both the chip cost and the complexity in the design of on-chip voltage regulator for stable DC extraction are greatly reduced. This design has been verified and realized by using a TSMC (Taiwan Semiconductor Manufacturing Company) 0.18-mum 1P6M standard CMOS technology.
Haemodynamic changes and vasopressin release are not consistently associated with carbon dioxide pneumoperitoneum in humans

Background: Conflicting haemodynamic changes, suggested to be caused by vasopressin release, have been reported during carbon dioxide (CO2) pneumoperitoneum. However, peritoneal stimulations including open surgery cause both a systemic vasopressor response and a vasopressin release, which are suppressed by opiate administration. Also, a decreased venous return of blood to the heart causes vasopressin release. Furthermore, previous haemodynamic assessments of laparoscopic surgery have been conducted using various anaesthetic regimens, which are likely to have caused various haemodynamic effects. We hypothesised that intraoperative haemodynamic and/or humoral changes would not be observed in association with laparoscopic surgery provided that, (a) normovolaemia is continuously maintained using transoesophageal echocardiographic (TEE) assessment, and (b) adequate depth of general anaesthesia is continuously maintained by bispectral index (BIS) monitoring and high plasma Ievel opiate administration.
The mobile Internet: Access, use, opportunities and divides among European children

Based on data collected through the Net Children Go Mobile survey of approximately 3500 respondents aged 9–16 years in seven European countries (Belgium, Denmark, Ireland, Italy, Portugal, Romania and the United Kingdom), this article examines the diffusion of smartphones among children and contributes to existing research on mobile digital divides by investigating what influences the adoption of smartphones among children and whether going online from a smartphone is associated with specific usage patterns, thus bridging or widening usage gaps. The findings suggest the resilience of digital inequalities among children, showing how social inequalities intersect with divides in access and result in disparities in online activities, with children who benefit from a greater autonomy of use and a longer online experience also reaching the top of the ladder of opportunities.
Infection of Nondividing Cells by Rous Sarcoma Virus

ABSTRACT A direct comparison demonstrates that Rous sarcoma virus is capable of infecting aphidicolin-arrested cells 10-fold more efficiently than murine leukemia virus but less efficiently than human immunodeficiency virus. The efficiency of infection of nondividing cells by the three viruses correlates with the respective ability of each viral DNA to enter the nucleus.
Co-clustering de données textuelles et continues

Le clustering est un outil essentiel pour l’analyse de donnees. C’est une maniere de resumer un jeu de donnees en formant des groupes homogenes d’observations (les clusters). Cependant, le phenomene «big-data »a fait croitre le nombre de variables, conduisant a l’emergence de jeux de donnees de grande dimension, parfois a un niveau tel que les techniques de clustering ne sont plus toujours adaptees pour discerner des structures. En effet, l’analyse d’un cluster repose generalement sur un representant de ce cluster (par exemple la moyenne). Neanmoins, ce dernier est lui-meme decrit par un grand nombre de variables, ce qui rend difficile l’interpretation et hasardeuse l’estimation. De cette observation nait le besoin de «resumer »aussi les variables, ce que leur regroupement en clusters peut permettre, de facon symmetrique au regroupement classique des individus en clusters. Le co-clustering est alors une methode candidate car elle realise un clustering simultane des lignes et des colonnes. Dans le cas de l’analyse de donnees textuelles, et notamment le clustering de document, le co-clustering est un theme largement etudie lors de ces dernieres annees. Cependant, la plupart des approches ne permettent pas de prendre en compte, en plus des donnees textuelles, d’autres variables. Le travail presente propose une extension du modele des blocs latents pour des jeux de donnees avec des variables textuelles et continues.