Miracle-dz/UniFAR-FTUs huggingface dataset:
Collaborative Hardware-Software Management of Hybrid Main Memory

DRAM has long been the preferred technology choice for main memory. With new challenges of high energy and scalability of DRAM, emerging non-volatile memory technologies, such as phase-change memory (PCM), are being considered. Typically, PCM is used in conjunction with DRAM to form a hybrid main memory. Exposing both the PCM and DRAM to the system software and managing it through the operating system (OS) is a viable architecture. The advantage of this organization is that current systems are more easily adapted to support a partitioned DRAM/PCM address space with only small changes to their design. In addition, this architecture is the easiest path forward to incorporate persistence in the main memory hierarchy by reserving part of PCM for storage. However, the performance of software-managed hybrid memory is not on par with hardware-only approaches, such as the DRAM cache. This is caused by the large granularity at which data is migrated (OS pages) and the low visibility that the OS has of the access patterns of applications. This thesis proposes an experimental framework for studying software-managed hybrid memory and uses it to understand the causes of its low performance. In addition, this thesis proposes and evaluates several hardware-software co-designed mechanisms to alleviate the performance impacts of managing hybrid memory in software. Lastly, this thesis proposes a new migration policy specifically designed to take advantage of the new hardware support. These contributions show that software-managed hybrid memory with specialized hardware support for migration and monitoring is a viable architecture for PCM-based hybrid main memory.
SILATIP Dit Reskrimsus Polda Jateng Unit Cyber Crime Menggunakan Metode Extreme Programming

The Special Criminal Investigation Directorate is the executing element of the main task under the Regional Police Chief, led by Dir Reskrimsus with the rank of Chief of the Police Commissioner (Kombes Pol) / Echelon II-B, tasked with conducting investigations and investigating special crimes, coordinate, supervise, and administer PPNS investigations in accordance with statutory regulations. So far, the Directorate of Criminal Investigation of the Central Java Regional Police, especially the Cyber Crime Unit, in its service still uses manual methods. This was felt to be inefficient because of the large number of complaints coming in and the lack of police personnel who handled complaints from reporters so that servants to the community were judged to be less than optimal and needed a long time in a complaint report. This study uses the Extreme Programming method in designing the developed system. Based on the analysis and discussion, it can be concluded that Extreme Programming is one method that supports the acceleration of the development of a small to medium scale system and can improve the quality of the system. Unfortunately, Extreme Programming does not have formal documentation so there is no measuring instrument that shows that the system has been completed.
Assessing students’ continuance intention in using multimedia online learning

The study aimed to assess the students’ continuance intention (SCI) in using multimedia online learning including students’ perceived usefulness (SPU), students’ ease of use (SPE), and students’ flow experience (SFE). There is no,so far, the assessment of students’ activity in using multimedia online learning within the extended Technology Acceptance Model (TAM). This study revealed the students’ continuance intentions in using online lessons.There were 523 students as the samples. They learned and examined the content of online English learning resources as well as multimedia aspects.TAM was used to predict the SCI. The results indicate that the students’ intentions are influenced positively by perceived usefulness, ease of use, and the flow experience. The SPU influenced more students’ motivation than SPE. It is recommended that designers of online learning should be more specific in determining target users. The online learners’ skill on ICT, pedagogical principles, and technological barrier in different region are among the determinant aspects for receiving positive enduring intention.
Expression of farnesyl diphosphate synthase gene(fps) in Nicotinan tabacum hairy root via Ri-mediated transformation

To improve phytoalexin synthesis capability of hairy roots,farnesyl diphosphate synthase gene(fps) of Mentha spicata L.was transferred into tobacco via Ri-mediated transformation.The engineering Agrobacterium rhizogenes strain Ar1334 harboured the binary vector pBinARfps,in which the fps cDNA was placed under 35S promoter.The leaf explants of K326 co-cultured with Ar1334 were transformed on MS medium to induce hairy roots.Among the 18 lines of hairy root induced,4 lines showed some kanamycin(20 mg·L1) resistance.All the transgenic hairy root lines showed typical hairy root characteristics on MS medium without any plant hormone.Polymerase chain reaction and Southern blot revealed the foreign gene fps was intergrated into these 4 lines.Northern blot analysis indicated that the foreign fps gene was expressed at the transcriptional level.Transgenic hairy root lines showed higher FPS activity than the control and disease challenge also proved that the juice of transgenic hairy roots could inhibit the growth of Alternaria alternata.This result proved that foreign fps gene expression could improve the accumulation of resistance substance in hairy roots in vitro culture.
Smart home system

The invention relates to a smart home system, which comprises a set-top box, a television, a wireless switch and an electric lamp. The set-top box comprises a processing center, a television interface, a wired network interface and a wireless network interface. The processing center is connected with the television interface and the wired network interface, connected with the wireless switch by the wireless network interface and used for receiving digital audio and video information by the wired network interface, decoding the received digital audio and video information into digital audio information and digital video information suitable for the television to play, transmitting the digital audio information and the digital video information suitable for the television to play to the television interface, and transmitting a light regulation signal to the wireless switch by the wireless network interface. The television is connected with the television interface, and is used for playing the digital audio information and the digital video information transmitted by the television interface. The wireless switch is connected with the electric lamp, and is used for controlling the on, off and light regulation of the electric lamp according to the light regulation signal. The smart home system can perform home control by utilizing the set-top box.
Regulating expressions of cyclin D1, pRb, and anti-cancer effects of deguelin on human Burkitt＇s lymphoma Daudi cells in vitro

Aim: To investigate anticancer effects and molecular mechanism of deguelin on human Burkitt' s lymphoma Daudi cells in vitro and compare the cytotoxicities of deguelin on Daudi ceils and human peripheral blood monocular ceils (PBMC). Methods: The effects of deguelin on the growth of Daudi cells were studied by 3-(4, 5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium (MTT) assay. Apoptos iswere dectected through Hoechst 33258 staining and Annexin V/PI double-labeled cytometry. The effect of deguelin on the cell cycle of Daudi cells were studied by a propidium iodide method. The expressions of cyclin D1 and pRb were checked by Western blot. Results: The proliferation of Daudi cells were decreased in deguelin-treated group with a 24-h IC50 value of 51.55 nmol/L. Deguelin induced Daudi cells apoptosis was in a time- and dose-dependent manner. G0/G1 phase increased and S phase decreased in Daudi cells treated with deguelin. With deguelin 0, 5, 10, 20, and 40 nmol/L treatment for 24 h, G0/G1 phase increased from 37.34% to 56.56%, whereas S phase decreased from 37.72% to 21.36%. PBMC was less sensitive to the cytotoxic effect of deguelin than Daudi cells. The expression of cyclin D1 and pRb protein were decreased sharply in Daudi cells treated with deguelin. Conclusion: Deguelin is able to inhibit the proliferation of Daudi cells by regulating the cell cycle that arrested cells at Go/G, phase and inducing the cell apoptosis. Moreover, deguelin selectively induced apoptosis of Daudi cells with low toxicity in PBMC. The antitumor effects of deguelin were related to downregulating the expression of cyclin D 1 and pRb protein.
'Pre-synaptic' vesicular glutamate release mechanisms in osteoblasts.

Identification of intercellular signalling pathways in bone represents an important therapeutic target for drug development in the treatment of clinical conditions such as osteoporosis. One such intercellular signalling pathway in bone appears to be mediated by the excitatory amino acid glutamate, exhibiting remarkable similarities to synaptic neurotransmission. Bone cells (osteoblasts and osteoclasts) express functional glutamate receptors that are electrophysiologically and pharmacologically similar to those expressed in the CNS and there is evidence for their involvement in both bone formation and bone resorption. However, to date the cellular source of glutamate for the activation of these specific glutamatergic receptors in bone has remained unclear. This review provides a synopsis of our current understanding of these 'pre-synaptic' signalling mechanisms, presenting compelling evidence that osteoblasts possess the molecular capability to direct regulated vesicular glutamate release in response to osteotropic regulatory inputs. In addition, we discuss mechanisms other than 'pre-synaptic' glutamatergic mechanisms that could account for the source of glutamate for receptor activation in osteoblasts. Finally, convincing evidence reporting physiologically released glutamate in varied osteoblasts and osteoblastic cell lines is discussed. The overwhelming conclusion of this review is that by defining both the characteristics and regulatory control of this process, highlighting both similarities and differences between the CNS and bone may provide compelling evidence for the role of glutamate in bone cell function and physiology.
Examining the relationship between the Big Five, Grit and avoidance of automated communication scales in adults 40–65

ABSTRACT Automated communication technologies (ACTs) have largely become commonplace in the day to day life. Although these technologies are widely used, there is a not insubstantial proportion of the population that prefers to avoid contact with ACTs. Recently, a scale was developed to assess dispositional avoidance of automated communication technologies. The current study provides validation of the scale in an older adult population and demonstrates that the avoidance of automated communication scale can be discriminated from personality measures, including the Big Five and Grit, and is predictive of avoidance of ACTs.
Hessenberg Elm Autoencoder Kernel For Deep Learning

Deep Learning (DL) is an effective way that reveals on computation capability and advantage of the hidden layer in the network models. It has pre-training phases which define the output parameters in unsupervised ways and supervised training for optimization of the pre-defined classification parameters. This study aims to perform high generalized fast training for DL algorithms with the simplicity advantage of Extreme Learning machines (ELM). The applications of the proposed classifier model were experimented on RespiratoryDatabase@TR. Hilbert-Huang Transform was applied to the 12-channel lung sounds for analyzing amplitude-time-frequency domain. The statistical features were extracted from the intrinsic mode function modulations of lung sounds. The feature set was fed into the proposed Deep ELM with the HessELM-AE. The proposed model was structured with 2 hidden layers (340,580 neurons) to classify the lung sounds for separating Chronic Obstructive Pulmonary Disease and healthy subjects. The classification performance was tested using 6-fold cross-validation with proposed Deep. HessELM-AE has achieved an influential accuracy rate of 92.22% whereas the conventional ELM-AE has reached an accuracy rate of 80.82%.
The Reciprocal Modulation Between Epigenetic and microRNA and The Application for Treatment of Malignant Tumors

The recent investigations have demonstrated that epigenetic such as DNA methylation and histone modification was closely associated with cell growth and malignant tumors, and epigenetic modification was responsible for an important cause of oncogenesis. However, for the recent years some observations have been also shown that the development of tumorigenesis was attributed to transformation expression in microRNA. The latest investigations have revealed that epigenetic was involved in modulation of microRNA expression, on the contrary some kinds of microRNAs could also control epigenetic, moreover, the reciprocal modulation between microRNA and epigenetic could regulate gene expression and induce tumorigenesis. At the same time the data likewise displayed that epigenetic adjusted microRNA expression principally in a way of DNA methylation or histone modification, nevertheless microRNA regulated epigenetic by way of methyltransferases expression, DNA methylation maintenance and histone modification. With regard to the reciprocal modulation between microRNA and epigenetic, a comprehensive and systemic review of reciprocal relationship in modulation of cell growth and oncogenesis was gived.
The Systems Biology of hearing Evolution in Vertebrates

The evolution of vertebrates from water to land experienced a series of important changes, in which mechanosensation should be one of the most apparent events. The lateral line organs on the fish's both sides can perceive the water pressure and maintain stably their body in water. As to the hearing sensation on fish, it is not clear yet, although it has a pair of ears. However, the terrestrial vertebrates evoled from fish in water have to depend the auditory feeling. The auditory perception or hearing is apparently different from other senses, which is going around individual, without actually paying attention to its environment. It is always working, day and night, to warn of danger for the animal itself. In addition, it also helps the animal to mate. This paper discusses the morphological evolution for hearing in vertebrates living from water to land, and explores the molecular aspects according to the advances in hearing in vertebrates. Obviously, this is a view from systems biology.
Using video quality metrics for something other than compression

The development of video quality metrics and perceptual video quality metrics has been a well established pursuit for more than 25 years. The body of work has been seen to be most relevant for improving the performance of visual compression algorithms. However, modeling the human perception of video with an algorithm of some sort is notoriously complicated. As a result the perceptual coding of video remains challenging and no standards have incorporated perceptual video quality metrics within their specification. In this paper we present the use of video metrics at the system level of a video processing pipeline. We show that it is possible to combine the artefact detection and correction process by posing the problem as a classification exercise. We also present the use of video metrics as part of a classical testing pipeline for software infrastructure, but here it is sensitive to the perceived quality in picture degradation.
OBSERVATIONS ON GIZZARD ULCERS IN BABY CHICKS

Because so many gizzard ulcers are found in necropsies of baby chicks, a study was made of this condition. Although the lesions have been called erosions for some time, the majority observed in our work completely perforated the gizzard lining. Bottorff (1) reported observing hemorrhages in the gizzard lining of 18-day embryos in the early 1930's. Hutyra et al. (2) discussed stomach ulcers in domestic animals, including fowl, and attributed them to local circulatory disturbances. Scott (4) reported that erosions were probably the result of a deficiency of bile acid production or secretion. Many other causes have been proposed.
Obstacle Avoidance-Formation Control of Mobile Robotic Network with Coordinated Group Stabilization

We present a distributed control law for a group of agents that solves the problem of formation control with obstacle avoidance and that can be combined with a coordinated group stabilization control law. In particular, we consider a control law that is given by a linear combination of distributed formation, distributed obstacle avoidance and centralized group motion control laws. Simulation results show the effectiveness of our proposed control law.
Identification and Separation of Endophytes in Wild and Cultivated Glycyrrhiza Uralensis from Gansu Province

Objective: To compare the differences of biological activity between wild and cultivated glycyrrhiza uralensis through the isolation of endophytes and identification on dominant bacteria from endophytes of different species in the same genera.Method: Endophytes from wild and cultivated GanCao were isolated and purified with NA and PDA base.The dominant bacteria were compared and judged with frequency separation.Result: All 65 strains of endophytic bacteria and seven strains of endophytic fungi were isolated from wild GanCao,the dominant bacteria were penicillium spp and monillales;54 strains of endophytic bacteria and six strains of endophytic fungi were isolated from cultivated GanCao,the dominant bacteria were penicillium spp;endophytic fungi isolated from wild and cultivated GanCao were in the six genera,there were five same genera,two different genera were rhizoctonia and trichoderma.Conclusion: Wild and cultivated GanCao have almost the same amount and kinds of endophytic bacteria and fungi,but there exists remarkable difference in genera and dominant bacteria of endophtic fungi in both.
Differential Expression and Gene Cloning of Peroxiredoxin from Nostoc flagelliforme Subjected to Dehydration and Rehydration

Nostoc flagelliforme is a terrestrial nitrogen-fixing cyanobacteria with strong drought ecological adaptability.In this research,2-DE,gel image analysis and MALDI-TOF-TOF/MS were applied to compare and identify the peroxiredoxin expression level from N.flagelliforme subjected to dehydration and rehydration.Degeneracy primer was designed based on the identified amino acid sequences in order to clone peroxiredoxin gene,to analyze the gene and amino acid sequences,to predict the secondary structure of peroxiredoxin,and to study the prokaryotic expression of the peroxiredoxin gene.The results indicated that peroxiredoxin expression level of N.flagelliforme subjected to rehydration was higher than that to desiccation.Peroxiredoxin gene was cloned and a full length of 639 bp DNA was obtained(GenBank access number: HM854286). Homology analysis showed that the N.flagelliforme peroxiredoxin gene has high consensus regions.The secondary structure of peroxiredoxin was made up of α helix,β strands and random coil.Peroxiredoxin gene was expressed in E.coli,and a Mr 26.5×103 heterologous protein was obtained.It was confirmed by Western blotting that the protein was peroxiredoxin.The study laid a foundation for in depth research in terms of the drought-resistant molecular mechanism and protection mechanism of N.flagelliforme in extreme arid environment.Fig 10,Tab 1,Ref 25
An approach to quality improvement of Nigerian university library services: A framework for effective quality management implementation

The paper explores the different strategies in managing operations and delivering services and compares them to current trends in academic libraries in Southwestern (SW) Nigeria. The author objectively and comparatively examined the different models of quality management (QM) and strategies, from which a framework of quality improvement for Nigerian university libraries was developed. The article employed a pragmatic approach to unearth the complexities of investigating the phenomenon in academic library environments. This paper discussed the findings of three studies (online survey, interview and focus groups) in this research and how they relate to the existing literature. A comprehensive analysis highlights challenges of university library operations in SW Nigeria while a pragmatic approach was used to achieve the objectives of the paper. The paper concluded that improvement in quality of service delivery and operations is certain if the proposed framework for QM implementation is embraced in Nigerian academic libraries. Recommendations were made on the way forward toward improving academic library services nationwide.
Tissue distribution and content of Cry1Ab insecticidal protein in the Bacillus thuringiensis resistant and susceptible Asian corn borer larvae fed on Bt-transgenic corn

The distribution and content of Cry1Ab insecticidal protein in different tissues of the Asian corn borer,Ostrinia furnacalis(Guenee),when the 3rd instar larvae of Cry1Ab protein resistant and susceptible colonies fed on whorl leaves of Bt-transgenic corn expressing Cry1Ab protein for 3 days were determined and analyzed by enzyme-linked immunosorbent assay(ELISA). The distributions of Cry1Ab in different tissues in the resistant and susceptible larvae were similar,mainly in the midgut tissue and haemolymph.The Cry1Ab contents in the midgut tissues of the resistant larvae with and without contents inside their midguts were 277.2 ng/g and 52.7 ng/g,respectively,significantly higher than those of the susceptible larvae,which were 104.9 ng/g and 40.1 ng/g,respectively.The Cry1Ab contents in the haemolymph of the resistant and susceptible larvae were 93.7 ng/g and 69.5 ng/g,respectively.The Cry1Ab protein in the silkgland and Malpighian tubules in the resistant and susceptible larvae could be detected,but the concentration was quite low.No Cry1Ab protein was detected in the fat body and reproductive organs,pupae,adults and eggs by ELISA method both in the resistant and susceptible larvae fed on the Bt corn.The results suggested that the Cry1Ab protein from larvae feeding on Bt corn could not be biotransferred to the subsequent pupae,adults and eggs.
Real-Time Feedback Systems, Recordkeeping and the Task Selection Bias

With the emergence of new technologies, the use of real-time feedback systems where employees have a choice over whether and how frequently they want to get feedback is increasing. In this study, we experimentally examine individuals’ tendency to choose easier tasks over difficult tasks (also known as the task selection bias) under real-time feedback systems. We find that real-time feedback systems lead to a higher task selection bias and that recordkeeping can reduce the task selection bias induced by real-time feedback systems. Our findings also reveal that planning and dynamic sequencing (where the system suggests the next task based on a plan) do not have an incremental effect over recordkeeping in reducing the task selection bias. Our study uncovers how modern accounting systems influence task selection and tests how real-time feedback systems could be modified to mitigate the task-selection bias induced by real-time feedback systems.