Miracle-dz/UniFAR-FTUs huggingface dataset:
Compensation of Current Harmonics by means of Multiple Generation System with Doubly-Fed Induction Generators

The paper presents the topology of a system of power generation connected to a grid based on two doubly-fed induction generators (DFIG) with selective current harmonic compensation capabilities. The scheme uses a grid-side converter supplying DC voltage with two rotor-side converters. A grid-side converter is linked to the network as well as each of the rotor-side converters are associated to the respective generator rotor. DFIG's basic control algorithm aims primarily to obtain maximum power output of wind at variable wind speeds. The possibility of improving the electric energy quality within the power of the converter is realized by compensating the grid current harmonics. The control purpose of the rotor-side converter is to generate a maximum of active power and improve quality of power. The harmonic components of the current are distributed for compensation by two generators separately. To demonstrate the usefulness of the scheme the whole generation system is simulated. The results of simulation are presented.
In Process Quality Control Factors Affecting Potency of Fowl Cholera Vaccine

Fowl cholera (FC) is one of the respiratory syndromes of commercial layer, breeder and broiler farms in Pakistan. The disease is mainly controlled by vaccination. In the present study, effect of “in process quality control” factors such as amount of immunogen, chemical nature of adjuvant, fractions of bacterial culture and its storage on potency of the vaccine was investigated. Immunogen amount (1011CFU/ml) induced serum anti-Pasteurella multocida ELISA (anti-PM-ELISA) antibody titer in the vaccinated birds on 32 days post vaccination that was significantly higher (P<0.05) than that of 109 and 1010CFU/ml. Montanide based whole culture vaccine induced better antibody response as compare to aluminum hydroxide gel. Washed culture of P. multocida (bacterial sediment) induced significantly higher anti-PM-ELISA antibody titer as compared to the vaccine prepared from purified LPS or whole culture vaccine (p<0.05). Storage of oil based FC vaccine at refrigerated temperature for six months did not affect its immunogenicity. It is concluded that amount of immunogen, chemical nature of adjuvant, freeing of bacterial culture from LPS and media components and maintenance of cold chain are in process quality control factors affecting potency of the vaccine.
LOW COST WIRELESS ECG PATCH USING ESP32

Wearable-and-wireless Electrocardiograph (ECG) has been widely used for long term monitoring due to practical reasons. Besides its high Signal to Noise Ratio (SNR), one of patch benefits is its flexibility for users to place the electrodes. However, most of existing commercial wireless ECG patches displays Heart Rate Variability (HRV) only, without ability to provide or record the ECG waveform. Some of them employ two electrodes only: Right Arm (RA) and Left Arm (LA), without additional electrode called Right Arm Drive (RLD). In addition, It is beneficial to provide more than one wireless technology option for ECG patch. We propose a low cost wireless ECG patch that has ability to provide ECG waveform (Lead I) and calculate HRV automatically. Besides RA and LA, it utilized RLD electrode to increase Common Mode Rejection Ratio (CMRR). For data processing, we employed ESP32, a low-power 32-bit microcontroller equipped with Bluetooth Classic (BT), Bluetooth Low Energy (BLE), and Wifi in a compact module. The test results showed that the proposed ECG patch resulted in more accurate HRV calculation as well as 2,7 times faster transition time compared to a commercial product.
Transient spectral events in resting state MEG predict individual time-frequency task responses

Even in response to apparently simple tasks such as hand moving, human brain activity shows remarkable inter-subject variability. Presumably, this variability reflects genuine behavioural or functional variability. Recently, spatial variability of resting-state features in fMRI - specifically connectivity - has been shown to explain (spatial) task-response variability. Such a link, however, is still missing for M/EEG data and its spectrally rich structure. At the same time, it has recently been shown that task responses in M/EEG can be well represented using transient spectral events bursting at fast time scales. Here, we show that individual differences in the spatio-spectral structure of M/EEG task responses, can, to a reasonable degree, be predicted from individual differences in transient spectral events identified at rest. In a MEG dataset of diverse task conditions (including motor responses, working memory and language comprehension tasks) and resting-state sessions for each subject (n = 89), we used Hidden-Markov-Modelling to identify transient spectral events as a feature set to learn the mapping of space-time-frequency content from rest to task. Resulting trial-averaged, subject-specific task-response predictions were then compared with the actual task responses in left-out subjects. All task conditions were predicted significantly above chance. Furthermore, we observed a systematic relationship between genetic similarity (e.g. unrelated subjects vs. twins) and predictability. These findings support the idea that subject-specific transient spectral events in resting-state neural activity are linked to, and predictive of, subject-specific trial-averaged task responses in a wide range of experimental conditions.
Investigating the Roles of Master Cell Cycle Regulators during Cytokinesis and Embryonic Development in Caenorhabditis elegans

Separase cleaves cohesin to allow chromosome segregation. Separase also regulates cortical granule exocytosis and vesicle trafficking during cytokinesis, both of which involve RAB-11. We investigated whether separase regulates exocytosis through a proteolytic or non-proteolytic mechanism. In C. elegans, protease-dead separase (SEP1::GFP) is dominant negative. Consistent with its role in cohesin cleavage, SEP1::GFP causes chromosome segregation defects. As expected, partial depletion of cohesin rescues this defect, confirming that SEP-1::GFP acts through a substratetrapping mechanism. SEP-1::GFP causes cytokinetic defects that is synergistically exacerbated by depletion of the t-SNARE SYX-4. Furthermore, SEP-1::GFP delays furrow ingression, causes an accumulation of RAB-11 vesicles at the cleavage furrow site and delays the exocytosis of cortical granules during anaphase I. Depletion of syx-4 further enhanced RAB-11::mCherry and SEP-1::GFP plasma membrane accumulation during cytokinesis, while depletion of cohesin had no effect. In contrast, centriole disengagement appears normal in SEP-1::GFP embryos, indicating that chromosome segregation and vesicle trafficking are more sensitive to inhibition by the 16 inactive protease. These findings suggest that separase cleaves an unknown substrate to promote the exocytosis of RAB-11 vesicles and paves the way for biochemical identification of substrates.
From greenway to sustainable tourism : experiential learning

impressions: Affection-based appreciation Visitors showed impressions on greenway activities in three main aspects. The first one is the “natural beauty appreciation”. People were impressed by the wild animals and the authentic nature (e.g. trees, water, sunshine, flowers and natural sounds), which were in strong contrast to the high-rise building landscape in daily life. People got close to nature and travelled in slow pace so that the details of the nature were appreciated, and romantic moments were recorded in their minds. As the participant HZ43 described: “I remembered the road where we encountered. I rode back slowly. I felt it was very beautiful. In this season there [Hangzhou], the leaves turned into the light green. It was pretty. You know, in Guangzhou where I worked now. I cannot see leaves in that spring color” (HZ43P). This moment would be an unforgettable life envision with happy and hope to recall in future. The meaning behind is not just nature and greenway trip, but the discovery of beauty in life. Secondly, abundant “physical exercises and entertainments” were mentioned in follow-up interviews. Similar to the on-site discussion, cycling was the most popular one to be mentioned. Notably, it is the group cycling with family members and friends that people preferred because it represented happy memories with others: “I shared the cycling experience with my wife after I returned home. Because I felt cycling together on Qiandao Lake Greenway was enjoyable. Particularly the weather was good to support. I told her this thing” (HZ47P). Other outdoor entertainments like kite flying, BBQ and games contained the same meaning so that they were still appreciated after trips. Walking along the greenways was also an impressive activity due to the peaceful and interesting moments it brought to visitors. It could be concluded that physical exercises became memorable with affection attached to it. The last type of activities inscribed in visitors’ minds is the “self-immersed thinking”. They appreciated the space and time that greenway trips provided for free thinking on past, current and future life: “I dreamed there and thought where I would be in future. When I had an overview of the city, I thought where I would work and where I would live, things like that” (SZ01P). In high-paced daily routine, it was really luxury for people to spare time for pure thinking without distractions.
Dientamoeba fragilis: um parasito enigmático

Foram abordados os principais aspectos relativos à morfologia, biologia, epidemiologia e possível patogenicidade de Dientamoeba fragilis, protozoário intestinal atualmente classificado como pertencente à ordem Trichomonadida.Descritores: Dientamoeba, Dientamebíase, Trichomonadida, Infecções por protozoários, Enteropatias parasitárias
Fonksiyonel Besinlerin Kolesterol Metabolizması Üzerinde Etkisi

Total kolesterol ve dusuk yogunluklu lipoprotein, koroner kalp hastaligi ile guclu iliski gosterdiginden dolayi, kolestrol her zaman onemli konulardan biridir. Kolesterol homeostazisi, sterol emilim, biyosentez, katabolizma ve atiliminin kompleks bir mekanizmasi ile saglanir. Son yillarda, dislipidemi kontrol ve tedavisini iyilestirmek ve optimize etmek icin nutrasotikler ve fonksiyonel besinlerin olasi kullaniminda, artan bir ilgi olmustur. Total kolesterolu dusuren nutrasotikler ve fonksiyonel besinler, kolesterol homeostazini duzenleyen genleri etkilemesi gerekmektedir. Genel olarak, kolestrol dusurucu fonksiyonel besinler ve nutrasotikler, intestinal Niemann-Pick C1 benzeri 1 (NPC1L1) rakipleri, asil CoA: kolestrol asiltransferaz (ACAT) inhibitorleri, 3- hidroksi-3-metilglutaril (HMG-CoA) reduktaz inhibitorleri, LDL reseptor aktivatorleri, kolesterol-safra asidi emilim inhibitorleri ve plazma kolesteril ester tasiyan protein (CETP) inhibitorleri, kolesterol-7α-hidroksilaz (CYP7A1) aktivatorleri olarak yedi tipte siniflandirilabilirler. Bu derlemede, bazi onemli kolestrol dusurucu nutrasotikler ve fonksiyonel besinler ve kolesterol dusurucu mekanizmalarini incelemektedir.
Acute Toxicity and Ecological Risk Assessment of Benzophenone and N,N-Diethyl-3 Methylbenzamide in Personal Care Products

Benzophenone (BP) and N,N-diethyl-3-methylbenzamide (DEET) are two chemicals often used in personal care products (PCPs). There is a lack of systematic ecotoxicological evaluations about the two chemicals to aquatic organisms. In the present study, the acute toxic effects on Chlorella vulgaris, Daphnia Magana, and Brachydanio rerio were tested and the ecotoxicological risks were evaluated. For BP, the 96-h half-maximal effective concentration (EC50) on C. vulgaris was 6.86 mg/L; the 24-h median lethal concentration (LC50) on D. magana was 7.63 mg/L; the 96-h LC50 on B. rerio was 14.73 mg/L. For DEET, those were 270.72 mg/L, 40.74 mg/L, and 109.67 mg/L, respectively. The mixture toxicity of BP and DEET, on C. vulgaris, D. magana, and B. rerio all showed an additive effect. The induced predicted no-effect concentrations (PNECs) for BP and DEET by assessment factor (AF) method are 0.003 mg/L and 0.407 mg/L, respectively. Both are lower than the concentrations detected from environment at present, verifying that BP and DEET are low-risk chemicals to the environment.
Squelette membranaire chez Paramecium Tetraurelia : analyse structurale et fonctionnelle de la famille multigénique des épiplasmines

Le cortex de la plupart des protistes cilies contient un squelette membranaire dont le principal element est l'epiplasme, une structure apposee a la membrane alveolaire interne. Chez la paramecie, l'epiplasme se presente sous forme d'ecailles independantes disposees autour de chaque appareil ciliaire ; il est compose d'une famille multigenique de proteines appelees epiplasmines. Nous avons realise une etude structurale de cette famille multigenique. L'analyse phylogenetique a permis de confirmer l'existence de 5 groupes d'epiplasmines divise chacun en deux sous-groupes a et b. L'utilisation de la methodologie HCA nous a permis de montrer que ces proteines sont modulaires et presentent un arrangement de leurs domaines structuraux. Elles peuvent ainsi etre regroupees en trois classes symetriques, asymetriques et atypiques. L'analyse des regions 5'UTR des membres de cette famille multigenique montre la presence d'elements putatifs de regulation d'expression. La comparaison des epiplasmines de la paramecie avec leurs orthologues de Tetrahymena montre une relation structurale entre les groupes 1,2,3 et 5 et les EpiT 1,2,3, et 5 respectivement suggerant l'existence d'un ancetre commun pour l'epiplasme de Paramecium et Tetrahymena. Nous avons realise l'analyse fonctionnelle des epiplasmines a partir d'approche par ARN interference et par localisation couplee a la GFP. La perturbation de l'expression des epiplasmines symetriques et asymetriques, aboutit a une reponse cellulaire commune qui se traduit par un changement de la forme cellulaire, un blocage de la cytocinese et enfin l'apparition de formes plasmodiales. L'analyse du cortex par microscopie a fluorescence montre une alteration des unites corticales qui est fonction des types structuraux des epiplasmines. Les epiplasmines se localisent de maniere differentielle autour du corps basal definissant un territoire dont le modele d'organisation est centrifuge. On definit alors des epiplasmines cinetomosales, pericinetomosales, core et enfin peripheriques. Ce modele est discute en relation avec les phenotypes obtenus par l'analyse fonctionnelle. Il permet d'integrer les differents niveaux de relation entre le corps basal, son territoire et l'ensemble de l'epiplasme.
Study on the Mechanism of Buyang Huanwu Decoction for the treatment of Ischemic Stroke Based on Network Pharmacology

Background: Buyang Huanwu Decoction (BYHWD) is one of the representative prescriptions for tonifying qi and promoting blood circulation. This formula has been widely used in Chinese clinical practice for treatment and prevention of ischemic cerebral vascular diseases. However, the mechanism and active compounds of BYHWD used in clinical practice for ischemic stroke are not well understood. The purpose of this study was to understand the potential active components of BYHWD and further explore its mechanism of improving ischemic stroke. Methods: This study was based on network pharmacology and bioinformatics analysis. The compounds of BYHWD were obtained from public databases. Oral bioavailability as well as drug-likeness were screened by using absorption, distribution, metabolism, and excretion (ADME) criteria. Then, components of BYHWD, candidate targets of each component and known therapeutic targets of ischemic cerebral were collected. A network of compound-target genes and compound-ischemic cerebral was established by means of network pharmacology data sources. The enrichment of key targets and pathways was analyzed by using string database and DAVID database. In addition, we verified three key targets predicted by western blot analysis (IL6, VEGFA and HIF1A). Results: Network pharmacology analysis results of BYHWD identified 7 herbs, 42 compounds and 79 target genes associated to cerebral ischemia. The 10 key compounds were baicalein, beta-carotene, Baicalin, kaempferol, luteolin, quercetin, hydroxysafflor yellow A, isorhamnetin, Bifendate, formononetin,Calycosin, AstragalosideIV, Stigmasterol, sitosterol, Z-ligustilide, Dihydrocapsaicin. Core genes in this network were IL6, TNF, VEGFA, HIF1A, MAPK1, MAPK3, JUN, STAT3, IL1B and IL10. And pathways TNF, IL-17, Apoptosis, PI3K-Akt, Toll-like receptor, MAPK, NF-kappa B and HIF-1 signaling pathway, etc. related to ischemic stroke were identified. In vitro experiments, The results showed that compared with the control group (no treatment), BYHWD could significantly inhibit the expression of IL6 and increased the expression of HIF1A and VEGFA. Conclusions: Network pharmacology analysis can reveal close interactions between multi-components and multi-targets, and enhance our understanding of the potential effects of BYHWD in cerebral ischemia.
Trabeculectomy in Congenital Glaucoma; Experience in Helpers Eye Hospital Quetta

Purpose: To evaluate outcomes of trabeculectomy in terms of IOP control and its safety in terms of peroperativeand post-operative complications in Primary Congenital Glaucoma.Study Design: Interventional Case-Series.Place and Duration of Study: Helpers Eye Hospital, Quetta, from June 2017 to December 2018.Material and Methods: Thirty eyes of 17 patients were included in this case series after diagnosis of primarycongenital glaucoma. Patients with secondary congenital glaucoma due to trauma, surgery, inflammation, SturgeWeber Syndrome, Neurofibromatosis, cataract, uveitis, aphakia and pseudophakia were excluded from the study.Informed consent was taken from parents. Examination under anesthesia was done before surgery to recordpreoperative IOP, corneal diameter and anterior and posterior segment abnormalities. Primary trabeculectomywas done. Post-operative IOP and corneal diameter was recorded at 1st, 3rd and 6th month and every 6 monthsthereafter under general anesthesia. IOP at 12th month of surgery was the final outcome which was consideredsignificant if IOP was less than 21 mm Hg with stable corneal diameters.Results: Mean preoperative IOP was 25.8 mm Hg. Twenty-three (76.66%) eyes out of 30 eyes were consideredsuccessful with mean IOP of 15.3 mm Hg at last follow-up while 7 (23.33%) cases of failure were observed withpostoperative mean IOP of 27.71 mm Hg. These patients underwent additional surgeries to control IOP.Hyphema was the only complication observed in this study. Postoperative cataract developed in 5 eyes.Conclusion: Primary trabeculectomy is an effective operation and safe surgery for primary congenital glaucoma
Thérapies innovantes et approches relationnelles dans la prise en charge des hallucinations auditives persistantes de la schizophrénie résistante et ultra-résistante : revue de la littérature

La schizophrenie est un trouble psychiatrique chronique qui pose des defis therapeutiques considerables puisqu’un patient sur trois demeure resistant aux traitements et souffre de symptomes persistants et invalidants comme les hallucinations auditives. Recemment, la therapie AVATAR utilisant la realite virtuelle a montre un large effet therapeutique sur la severite des hallucinations auditives verbales en permettant aux patients d’engager un dialogue avec une representation informatisee de leur(s) voix, prenant a contre-pied les pratiques psychotherapiques plus largement repandues consistant au contraire a inciter les patients a ne pas porter attention a leurs voix. Le but de ce travail est de presenter les principes de cette therapie innovante a travers une revue de la litterature.
A Review on the Concept of Deep Learning

Artificial Neural Networks (ANN) has a number of application areas ranging from economic analysis to image processing and recognition. ANN is used by many online stores in the form of recommendation systems to offer suitable products based on their liking. Not only this, artificial neural networks are used these days for routing and navigation systems as in case of unmanned vehicles, antivirus software, etc. In this work based on artificial neural network recurrent and convolutional network is proposed at the level of letters in order to classify and sort textual information with given classes.
A Method of Searching for Optimal Coalition Structure for Solving Resource Scheduling Problem of Overall Load Balancing in Edge Computing Environments

The cooperative computing resource scheduling problem in the distributed computing environment is usually transformed into the problem about how to find the optimal coalition structure. However, affected by factors such as high node density and large number of concurrent tasks in edge computing environments, it is difficult to formulate resource scheduling schemes for overall load balancing in a large strategic space by traditional methods. In order to solve this problem, we proposed a method of searching for optimal coalition structure based on discrete particle swarm optimization (DPSO). Firstly, we converted the resource scheduling problem of edge computing into an optimization problem model, constructed a new structure of coalition structure to express the resource scheduling scheme, and gave key elements such as optimization objectives, decision variables, and constraint conditions. Secondly, we improved DPSO and designed M-ary discrete particle swarm optimization (MDPSO): improved particle state determination method for adapting to the new expression of the coalition structure, and proposed a power series-based inertia weight computing method to improve the optimization speed and the optimal solution quality. Finally, we simulated real application scenarios and designed comparative experiments on the optimization speed, the optimal solution quality, stability, etc., which verifies that the method proposed in this paper has obvious advantages in solving the resource scheduling problem of overall load balancing in edge computing.
Privacy as Civil Right

As the first U.S.-born Hispanic senator, Senator Dennis Chavez of New Mexico left a rich legacy of advocacy for civil rights and civil liberties. In this lecture, the fourth U.S. Senator Dennis Chavez Endowed Lecture on Law and Civil Rights, I explore an idea at the intersection of those two bodies of law: the right to privacy. In 2020, the hallmark of surveillance is its ubiquity; “everyone is watched. ” Unfortunately, this discourse erases the fact that, across American history, the burdens of government surveillance have fallen overwhelmingly on the shoulders of immigrants, heretics, people of color, the poor, and anyone else considered “other. ” Inspired by the legacy of “El Senador,” I trace that history from the English Puritans we now know as Pilgrims to the immigrant children detained at the southern U.S. border. I go on to argue that if we acknowledge the “color of surveillance,” we must reckon with its consequence. If surveillance is a tool used to threaten the vulnerable, we must understand privacy not just as a civil liberty, but also a civil right: A shield that allows the unpopular and persecuted to survive and thrive.