Miracle-dz/UniFAR-FTUs huggingface dataset:
Improving Scalability of Cloud System based on Routing Algorithms

computing provides end users with computing resources based on virtualization technologies at the data center. This allowed us to optimize data centers utilization by using techniques and algorithms that optimize the use of cloud computing resources. By taking advantage of some useful proprieties of routing algorithm proposed model is presented in the field of cloud computing that makes data centers more flexible and scalable. Our experimental results indicate that proposed model increases utilization of data centers resources and reduce waiting time. Keywordscomputing; Queuing models; Routing algorithms.
Proposed Canadian Voluntary National Johne's Disease Prevention and Control Program.

J ohne’s disease (JD) has emerged as a disease requiring a national prevention and control program due to mounting evidence and concern over production losses and the possible restrictions to international movement of cattle, as some countries require testing. In addition, because DNA from Mycobacterium avium subsp. paratuberculosis (MAP) has been found in 69% of humans with Crohn’s disease, MAP may be either a factor in the causation of this disease (1) or just an opportunistic organism found in the intestines of Crohn’s disease patients. A review into this potential relationship is beyond the scope of this paper, but further information is available from the Paratuberculosis Awareness and Research Association Web site (2). A number of countries have developed national, government-funded, animal health programs to provide logistical, administrative, and funding support to control JD (3,4). Recently, the Canadian Animal Health Coalition has coordinated the foundation of the official Canadian National Voluntary Johne’s Disease Prevention and Control Program (CJDPCP) and, subsequently, working subcommittees of that program. The proposed national program has 2 distinct pathways for both dairy and beef herds to participate in: The pathway for herd testing (status pathway [SP]), which builds on an existing voluntary program in Alberta, and the pathway for prevention of disease dissemination (prevention pathway [PP]), which, with minimal testing, builds on a pilot project in Ontario that, recently, has been expanded into western Canada. In this paper, the direction in which the national committee is headed with the CJDPCP is outlined, though the details are yet to be finalized, and the proposed CJDPCP is described in some detail with a view to instigating discussion among Canadian cattle producers and veterinary practitioners servicing the cattle industry. One of the goals of the CJDPCP is to ensure producer participation through ease of enrollment. The 2 pathways provide flexibility to allow herds to participate to varying degrees. Only some herds will have a goal of vigorous testing to validate their low prevalence status. To achieve the objective of decreasing MAP-prevalence nation-wide, positive herds will be particularly targeted. Support and education will be provided for those herds to minimize the spread of the disease within and among herds and, thus, have a positive impact on lowering the incidence of new MAP-infections. In addition, penalties for herds that test positive in the testing pathway will be kept to a minimum, so that herds will still be encouraged to participate at some level. Implementation of the program will be carried out at a provincial level, with the assistance of a national coordinator (yet to be determined), and confidentiality of herd results will be strictly maintained. The validity of the program and its impact on the national herd level of infection will be assessed through a concurrent research program conducted at various facilities across the country.
Resistance Exercise Training Attenuates Wasting of the Extensor Digitorum Longus Muscle in Mice Bearing the Colon-26 Adenocarcinoma

Progressive wasting of skeletal muscle is a significant side effect of malignancy. Perturbations in protein metabolism contribute to this state of wasting. Resistance exercise increases protein synthesis and mass of healthy muscles and counteracts muscle wasting associated with several catabolic conditions. It is not known whether resistance exercise training can counteract cancer-induced muscle wasting. This study examined the effect of resistance exercise training on muscle mass and protein content in 9 mice bearing the colon-26 adenocarcinoma. The dorsiflexor (extensor digitorum longus [EDL] and tibialis anterior) and plantar flexor (soleus, plantaris, and gastrocnemius) muscles of 1 leg of the tumor-bearing and the control mice were stimulated to contract eccentrically and concentrically, respectively, using an electrical stimulation protocol consisting of 10 sets of 6 repetitions per session. The muscles were stimulated on alternate days for a total of 8 sessions. The weight and protein content of the stimulated EDL muscle in the tumorbearing mice were significantly higher (62% and 25%, respectively) than those of the nonstimulated EDL. Training did not have significant effects on the weight or protein content of the other muscles of the tumorbearing mice, nor did it have significant effects on the muscles of the controls. These findings demonstrated that resistance training attenuated cancer-induced muscle wasting and protein depletion in the EDL muscle. The lack of an effect of the same training protocol on the ED Lmuscle in the control mice suggests that the amount and intensity of exercise training that is adequate to attenuate muscle wasting may not be adequate to induce hypertrophy of healthy muscles.
Unbiased spectral estimation and system identification using short-time spectral analysis methods

The methods of system identification and spectral analysis are well documented in the literature. In this paper, we attempt to merge the methods of least-square system identification and short-time Fourier transform spectral estimation. Starting from the least-squares normal equations for a linear system identification problem and expanding the signals in short-time Fourier transforms, we derive a Toeplitz system of equations, the solution of which approximates the original least-squares equation solution. We then bound the error norm between the two solution methods and show the properties of the error by numerical methods. The resulting “spectral” estimation method is shown to completely remove the bias normally associated with previously proposed spectral estimation procedures. The method appears to be particularly useful when one is interested in linear system identification of very large systems (long impulses response) or for system identification in the presence of nonstationary (eg., hurst) noise. Extensive numerical results are included.
Using the User's Mental Model to Guide the Integration of Information Space into Information Nee

The study reported here tested the efficacy of an information retrieval system output summary and visualization scheme for undergraduates taking a Vietnam War history who were in Kuhlthau's Stage 3 of researching a history essay. The visualization scheme consisted of (a) the undergraduate's own visualization of his or her essay topic, drawn by the student on the bottom half of a sheet of paper, and (b) a visualization of the information space (determined by index term counting) on the top-half of the same page. To test the visualization scheme, students enrolled in a Vietnam War history course were randomly assigned to either the visualization scheme group, who received a high recall search output, or the nonvisualization group, who received a high precision search output. The dependent variable was the mark awarded the essay by the course instructor. There was no significant difference between the mean marks for the two groups. We were pleasantly surprised with this result given the bad reputation of high recall as a practical search strategy. We hypothesize that a more proactive visualization system is needed that takes the student through the process of using the visualization scheme, including steps that induce student cognition about task-subject objectives.
Irradiation necrosis of the head of the femur.

WITH THE increasing frequency of the use of high voltage roentgen rays in the treatment of malignant neoplasms, the effects on normal tissue have become increasingly important to the radiotherapist and to the clinician. Not the least important of these effects are the changes occurring in bone and cartilage, although they do not appear to be widely familiar from a clinical point of view. Nevertheless, changes occurring in bone as a result of irradiation therapy have been reported since 1903, and in this paper we wish to review briefly the pathologic process involved and to present 2 cases, 1 of which is the third to be reported involving a male patient, as examples of the pathologic and the clinical importance of postirradiation lesions. Wammock and Arbuckle1quoted Perthes, who described the effects of roentgen rays on epiphysial growth in 1903, and Cluzet, who in 1910 described delay in callus
Cryptic diversity of the ‘cosmopolitan’ harpacticoid copepod Nannopus palustris: genetic and morphological evidence

Nannopus palustris Brady, 1880 is a free‐living widely distributed harpacticoid copepod, which has been formerly assumed to be a single, cosmopolitan but highly variable species. We compared several geographically distant N. palustris populations in terms of their morphology and genetics. Populations from the White Sea (WS), the North Sea (NS), the Black Sea (BS) and two sympatric morphs from South Carolina, USA (SC notched and SC straight morphs), were considered. The NS, BS and to a lesser extent SC notched specimens were morphologically similar and partly coincided to the ‘canonical’ description of the species. By contrast, WS population showed remarkable anatomical and morphometric peculiarities that correspond to some earlier descriptions. Genetic analyses of mitochondrial (cytochrome b) and nuclear (28S rDNA) genes demonstrated the significant distinctness among WS, both SC and (NS+BS) populations, the latter two being genetically indistinguishable. Concordance between mitochondrial and nuclear gene trees and morphological data supports that N. palustris is in fact composed of several pseudo‐sibling species, which are genetically and morphologically divergent. Neither correlation between genetic divergence and geographical distance nor significant intrapopulation diversity was found for these species. Taxonomic status, distribution and phylogenetic relationships of the species within the Nannopus genus need to be reconsidered. A further subdivision of species complexes might have important implications for the analysis of biodiversity of benthic copepods and consequently for the interpretation of their (species‐specific) ecological function.
Service-oriented architecture

This paper attempts a definition of service derived by unifying its usage in practice. In doing so it identifies participant's perspective as separate from actual different usages. Using this as an aid, the paper analyses the criteria applied in the use of service and considers how these can be aligned to derive commonality underlying the usage. Also included is a brief outline of the way in which a service-oriented architecture following such a model would affect the practice and process of developing large-scale, distributed software systems.
Treatment of childhood renal cell carcinoma with lymph node metastasis: Two cases and a review of literature

Standard treatment for renal cell carcinoma (RCC) is radical nephrectomy with lymph node dissection. Stages I and II have encouraging prognoses, but Stage III with regional lymph node metastasis can be unfavorable. Adjuvant therapy for pediatric patients with advanced RCC with lymph node involvement or metastatic lesion has not been defined. Advanced pediatric RCC is reported in two patients (boys, aged 6 and 9 years: Stage IIIs, Robson; Stage III and IV, pTNM classification) treated by nephrectomy and lymph node dissection followed by postoperative interferon‐α (IFN), that can be used as an adjuvant therapy with side effects such as fever, bone marrow suppression, or decreased liver function. One is doing well for 7 years, another is suffered from lung metastases at 3 years after surgery. Although immunotherapy is expected to improve survival in pediatric patients with advanced RCC, surgical resection of renal and metastatic tumors remains the standard treatment. J. Surg. Oncol. 2000;75:266–269. © 2000 Wiley‐Liss, Inc.
The predictive value of gadolinium enhancement for long term disability in relapsing-remitting multiple sclerosis-preliminary results

As short-term MRI studies are increasingly being used to monitor disease activity in multiple sclerosis (MS) it is vital to establish if short-term MRI activity is predictive of long term clinical outcome. We followed up after 5 years a group of 10 benign (relapsing-remitting MS with a disease duration 410 years and EDSS 43) and 10 early relapsing-remitting patients who previously had monthly serial MRI scans for 6 months. In the early relapsing-remitting group median EDSS at entry to the initial serial study was three and in the benign group 2.5. At 5-year follow up, five of these 20 patients had developed a definite deterioration in EDSS. The median number of new enhancing lesions detected originally in the group that had deteriorated was 11 (7-17) compared to 0 (0-5) new enhancing lesions, for those who had not deteriorated (P50.05). There was a trend towards a higher baseline T2 lesion load in the group with a definite change in EDSS but this was not significant. This study suggests that short-term measurement of the number of gadolinium enhancing lesions may predict long term outcome in relapsing-remitting MS.
Transforming Growth Factor-@ (PI, ,82, and ,63) Gene Expression and Action during Pubertal Development of the Seminiferous Tubule: Potential Role at the Onset of Spermatogenesis

The potential role of transforming growth factor-p (TGFB) as a mediator of cell-cell interactions during the pubertal development of the seminiferous tubule was examined. Mesenchymal-derived peritubular cells and epithelial-like Sertoli cells were isolated from prepubertal, midpubertal, and late pubertal rat testes. The developmental expression of the multiple forms of TGFB (TGFPl, -82, and -83) in whole testis and isolated somatic cell types was determined using a nuclease protection analysis. TGFBI and TGFP2 mRNA expression was predominant in the immature testis and decreased at the onset of puberty. TGFB3 mRNA expression, the most abundant form of TGFP present, peaked at an early pubertal stage, coincident with the initiation of spermatogenesis. Peritubular and Sertoli cells expressed each isoform of TGF/3 during development. Peritubular cell mRNA expression of TGFPl, -82, and $3 decreased during pubertal development upon differentiation of this cell type. Sertoli cell expression of TGFPl increased slightly and plateaued during pubertal development. TGFP2 mRNA expression was evident only in immature prepubertal Sertoli cells. Sertoli cell mRNA expression of TGFB3 increased the onset the peak of expression the analysis whole testicular lmmunoblot analysis both peritubular and Sertoli cells proteins for TGFPl, and Analysis of the hormonal regulation of TGFP expression in Sertoli cell TGFj32
IMAGE BLUR CLASSIFICATION AND ESTIMATE PARAMETER VIA DEEP LEARNING

Image blur kernel classification and parameter estimation are critical for blind image deblurring. Current dominant approaches use handcrafted blur features that are optimized for a certain type of blur, which is not applicable in real blind deconvolution application when the Point Spread Function (PSF) of the blur is unknown. In this paper, a Twostage system using Deep Neural Network (DNN) and General Regression Neural Network. The proposed approach is to first classify the blur type using DNN and then identify its parameters using GRNN and DNN has been applied to the problem of blur analysis. In the blur type classification, this method attempts to identify the blur type from mixed input of various blurs with different parameters, rather than blur estimation based on the assumption of a single blur type in current methodology and then classify those features. Moreover, in the parameter identification, the edge detection on logarithm spectrum helps DNN to identify the blur parameters with very high accuracy. Experiments demonstrate the effectiveness of the proposed methods with better results compared to the abundant dataset. Keywords— Blur Kernel classification, Point Spread Function, Deep Neural Network, General Regression Neural Network.
IS THERE STILL A ROLE FOR THE CLASSICAL COX‐MAZE III?

Background: The incidence of surgery for atrial fibrillation (AF) is rising, paralleled by an increase in the types of lesion sets and energy sources used. These alternate energy sources have simplified the surgery at the expense of increased cost of consumables. The classical Cox‐Maze III is the gold standard therapy with a proven efficacy in curing AF. Our complete experience with this procedure is presented.
The Ferritin Genes: Structure, Expression, and Regulation

Storage of iron in the tissues occurs in the form of ferritin and hemosiderin. Evidence regarding the latter' supports the thesis that hemosiderin originates from ferritin that has undergone intracellular digestion of its protein shell, leaving the iron core, usually located inside the inspissated remains of secondary lysosoma1 vesicles. Ferritin and hemosiderin are thus components of a continuum. This paper focuses on fenitin. Ferritin has been identified in all types of living organisms: animals, plants, molds, and bacteria.2 Within the protein shell of ferritin, iron is first oxidized to the ferric state for storage as ferric oxyhydroxide. The advantage of this mechanism is that it removes excess iron from the cell sap where it could otherwise participate in peroxidation mechanisms. For example, a single parenteral dose of iron salts administered to rats has been found to result in a burst of ethane exhaled by animal^. ^ This is due to peroxidation of membrane-associated omega-3-fatty acids, a response that can be suppressed by raising intake of vitamin E. Such experiments and others emphasize that iron can generate free radicals detrimental to cell membranes and to other molecular structures. Ferritin is the antidote for this phenomenon. The hollo'w protein shell of ferritin is penetrated by channels through which iron enters and exits from the ferritin cavity. The protein shell has a molecular weight of about 5 x105, and is made up of 24 subunits of two types, a slightly heavier H (mol. wt. about 21,000) and a lighter subunit L (mol. wt. about 20,000). When ferritin isolated from a tissue is subjected to isoelectric focusing, it segregates into a series of isoferritins with varying proportions of H and L subunits in the shell.4 TABLE 1 shows that the H : L ratios for isoferritins in rat tissues display a progression throughout the isofocusing gradient, suggesting that the surface charges of H and L subunits differ and their proportions thus determine the PI of the ferritin shell. It will be noted that the H : L ratios for a given isofocusing pl are quite different in rat heart and liver (TABLE 11, suggesting that the H and/or L subunits in these two tissues have different surface charges. This could be due to tissue-specific differences in primary amino acid sequences or to posttranslational modifications from glycosylation or other changes. A knowledge of the number of expressed ferritin genes could allow a decision as to which explanation is favored.
Capacitor voltage balancing of five-level ANPC converter based on zero-sequence voltage injection using PS-PWM

This paper presents a capacitor voltage balancing method for the five-level active neutral-point clamped (5L-ANPC) converter using phase-shifted pulse-width modulation (PS-PWM), including the voltage balancing of DC-link capacitors and flying capacitors. With PS-PWM, the series connected switches are operated at fundamental frequency and the other switches are operated at a constant switching frequency. The relationship between the average neutral-point current and zero-sequence voltage is investigated and an optimum zero-sequence voltage can be calculated to regulate the neutral-point potential. The voltage across the flying capacitor is regulated by adjusting the switching duty cycles of two PWM signals, which varies the operation time of redundant switching states in each switching period. Simulation and experimental results are presented to verify the validity of this method.
Development and validation of a physical and psychosocial job-exposure matrix in older and retired workers.

OBJECTIVES A general population job-exposure matrix (GPJEM) including physical and psychosocial demands as well as psychosocial resources applicable to older and retired workers was developed. Its validity was evaluated by examining associations of physical demands and iso-strain (combination of high psychosocial demands and low resources) with health. METHODS Physical and psychosocial work exposures reported by 55-64 year olds were derived from the Netherlands Working Conditions Survey and linked to the Netherlands Standard Classification of Occupations 1992. A GPJEM with low, moderate, and high probability of exposure to demands and resources was developed. To examine associations with health, two groups of the Longitudinal Aging Study Amsterdam were selected: current (i.e. at the time of the interview, 55-64 years) and former workers (55-84 years). Linear and logistic regression models were applied. RESULTS Use of force and work in uncomfortable positions were significantly associated with functional limitations and self-perceived health (SPH), but not hip or knee osteoarthritis (OA), in current and former workers. A moderate probability of repetitive movements was associated with functional limitations in former workers. A high probability of repetitive movements was associated with functional limitations in current and former workers as well as with SPH and hip and knee OA in former workers. Respondents formerly exposed to iso-strain had significantly higher diastolic blood pressure and more often hypertension. No such associations were found in current workers. No association was found with cardiovascular disease. CONCLUSIONS The results suggest that our GPJEM accurately classifies jobs according to physical demands and, although less clearly, iso-strain.
Development of Restricted and Repetitive Behaviors From 15 to 77 Months: Stability of Two Distinct Subtypes?

A community sample of 192 parents reported on their children’s restricted and repetitive behaviors (RRBs) at mean ages 15 months (N = 138), 26 months (N = 191), and 77 months (N = 125) using the Repetitive Behavior Questionnaire-2 (RBQ-2). Consistent with previous factor analytic research, 2 factors were found at each age: 1 comprising repetitive sensory and motor behaviors (RSM), and the other comprising insistence on sameness behaviors including rigidity, routines, and restricted interests (IS). Regression analyses indicated that RSM and IS subtypes develop independently. RSM at 77 months was predicted only by RSM behaviors at 26 months and not by IS behaviors at either 15 or 26 months nor by RSM behaviors at 15 months. IS at 77 months was predicted by IS behaviors at both 15 and 26 months, but not by RSM behaviors at either 15 or 26 months. Our findings provide evidence that there is stability of 2 independent subtypes of RRBs, RSM and IS, across early childhood and that these subtypes develop independently of each other.