Miracle-dz/UniFAR-FTUs huggingface dataset:
Neutrophil gelatinase-associated lipocalin as a potential therapeutic integrator of glycolipid metabolic and inflammatory signaling

Metabolic disease can be triggered by chronic excess of lipids and glucose. On the other hand, inflammation can trigger insulin resistance or metabolic dysfunction under defined conditions. It is possible to enter the network from an inflammatory or metabolic gateway and still end up with the same vicious loop. In the past decade, much effort has been made to understand the mechanisms how lipids and glucose are handled by macrophages and how inflammation could promote the glycolipid metabolic related disease process. Here, we also provide an overview of these two fields. Metabolic dysfunction triggered inflammation, in turn low-grade chronic inflammation aggravated metabolic dysfunction, and end up with the vicious loop. Glycolipid metabolism and inflammation are highly integrated and the proper function of each is dependent on the other, which are the most essential requirements for survival. So, choose way of proper regulate and control of low-grade chronic inflammation in metabolic dysfunction is very important and useful under present conditions.
Tests to assist in the staging of cutaneous squamous cell carcinoma: a generic protocol

This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows: To determine the diagnostic accuracy of sentinel lymph node biopsy (SLNB) for the detection of nodal metastases (in the investigated nodal basin) for the staging of cutaneous squamous cell cancer (cSCC). To determine the diagnostic accuracy of imaging tests, including ultrasound, computed tomography, magnetic resonance imaging and positron emission tomography, alone or in combination, for the detection of any metastasis for the staging of cutaneous squamous cell cancer. To determine the diagnostic accuracy of imaging tests for the detection of nodal metastases in the staging of cutaneous squamous cell cancer. To determine the diagnostic accuracy of imaging tests for the detection of distant metastases in the staging of cutaneous squamous cell cancer. We will estimate these separately for those undergoing primary staging and those who have experienced a disease recurrence. Sources of heterogeneity We will consider a range of potential sources of heterogeneity for investigation in each individual test review. These may vary between reviews but may include the following. i. Population characteristics • Primary tumour site (head and neck, trunk, limb, and other) • Primary staging versus mixed or unclear populations (i.e. including staging of recurrent disease) 1 Tests to assist in the staging of cutaneous squamous cell carcinoma: a generic protocol (Protocol) Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. ii. Index test characteristics • Differences in test positivity thresholds iii. Reference standard characteristics • Reference standard used (histology, clinical or imaging-based follow-up)
Image acquisition of the test-object by the CVL-10 copper vapor amplifier and optical bunch

Images of the test object surface were obtained using a laser projection microscope and an optical bunch. Images of the surface of the test object at its different location in the experiment (the test object is located at the end of the optical bunch; the test object is located in a double focus lens; the test object is located after the optical bunch and optical system of two lenses) were obtained on the screen of a laser projection microscope.
Expression of D2-40 in Benign and Malignant Breast Lesions and Study the Correlation between Lymphovascular Density and other Prognostic Factors of Breast Cancer

Background: D2-40 is a mouse monoclonal antibody specific for human podoplanin and has been used in identifying lymphovascular invasion (LVI) of tumors; also its expression has been used as a marker for myoepithelial cells (MEC) of breast. Lymphangiogenesis, assessed as lymphovascular density (LVD), is the initial step of generalized tumor lymphovascular invasion (LVI). It also involves VEGF-C as the most important protein family. Lymphangiogenesis among breast cancer cases correlations with several clinicopathological factors are important to determine prognosis and treatment strategies, but results have been controversial and require clarification. Aim: The aims of this work (1) To explore the expression of D2-40 as a marker for myoepithelial cells (MECs) of the breast lesions, (2) To investigate the clinicopathological significance of VEGF-C, D2-40 expression and lympovascular density (LVD) in breast cancer patients. Methods: Sections from 88 paraffin-embedded archival specimens of breast lesions were selected to include benign breast lesions as fibrocystic changes of the breast and ductal hyperplasia (15 cases); and invasive breast cancer (73 cases). Immunohistochemistry (IHC) for D2-40, calponin and VEFG-C were performed and IHC staining results and the associations of intratumoral and peritumoral LVD were correlated with clinic-pathological features and prognosis were assessed. Results: D2-40 highlighted the MECs of benign breast lesions beside it identified lymphatic vessels and LVI in breast carcinomas. VEGF-C expression was significantly higher in invasive breast cancer than benign breast lesions (p < 0.01). VEGF-C (p < 0.001) expression was significantly associated with peritumoral LVD, but not intratumoral LVD. VEGF-C expression, peritumoral LVD and LVI were significantly associated with lymph node metastasis (p = 0.025, p = 0.006 and p = 0.017, respectively). Moreover, peritumoral LVD was an independent risk factor for axillary lymph node metastasis, disease-free survival in multivariate analysis. Conclusion: our results show that D2-40 is a reliable marker highlights MECs in benign breast lesions beside it is a useful tool for identification of LVI in breast carcinomas which reflecting a potential for lymphatic metastatic spread and possible poor prognosis. Our study also demonstrated that high expression of VEGF-C in invasive breast carcinoma may induce lymphangiogenesis in the peritumoral area. Peritumoral LVD appeared to be a potential
Turkish Adolescents’ Adherence to the Mediterranean Diet

Abstract This study aims to examine nutritional status and KIDMED of adolescents, and to determine their relation with some parameters. The study sample included a total of 497 students selected from high schools. Of the participants, 52.5 percent were females (n=261) and 47.5 percent were males (n=236). To determine the KIDMED index of adolescents, the independent t-test was used for gender. One-way ANOVA was used for the variables of age and Body Mass Index (BMI). The adolescents’ average score for KIDMED was 4.65±2.38. Of them, thirty-one percent had “poor” diet quality (<3), 58.4 percent had “average” diet quality (4-7) and 10.6 percent had “good” diet quality (>8). MedDiet is effective in providing a healthy life. It is important that governmental policies encourage people to follow this diet to prevent future health problems.
Averaging multiple facial expressions through subsampling

ABSTRACT When perceivers view multiple facial expressions shown concurrently, they can quickly and precisely extract the mean emotion from the set. Yet it is not clear how many faces in the set contribute to summary judgments, and how the variance among them influences this process. To address these questions, we used the subset manipulation and varied emotion variance of faces in the sets across three experiments. Sets containing sixteen faces, or a subset of faces randomly selected from the sixteen-face display were presented, and participants judged the average emotion of each face set on a continuous scale. Results showed that when emotion variance was relatively large (Experiments 1 & 2), only two faces in the set contributed to ensemble representations. In Experiment 3 where the emotion variance was smaller, around three to four faces were likely sampled. However, when directly comparing results from Experiments 2 and 3, there was no strong evidence supporting the impact of variance in averaging efficiency. Altogether, these new results suggest that the process of averaging multiple emotional facial expressions can be explained by capacity-limited subsampling. The claim that ensemble representations are capacity unlimited or can overcome the bottlenecks in visual perception might need to be reconsidered.
Using Reinforcement Learning to Tackle the Autonomous Recharging Problem

Navigation and object interaction are two diﬃcult, crucial tasks for autonomous mobile vehicles. These tasks are made even more challenging when the vehicle is in an unfamiliar environment. The task of autonomous refueling in an arbitrary environment encompasses both the navigation and object interaction tasks. In this paper, we propose a reinforcement learning model and training procedure which can take the ﬁrst steps toward eﬃciently learning to seek out and dock at a charging station using only a single on-board monocular camera. More speciﬁcally we address the task of rotating in place to ﬁnd the charging station and keep it centered in the camera’s ﬁeld of view. Our results show that using this method, the vehicle is able to successfully ﬁnd and maintain focus on the charging station with a success rate of 99 . 4%.
Öğretim Elemanlarının Bilgi ve İletişim Teknolojilerine Yönelik Kabulleri ve Teknostres Algıları Arasındaki İlişkinin İncelenmesi

Calismanin amaci, ogretim elemanlarinin bilgi ve iletisim teknolojilerine yonelik kabulleri ve teknostres algilarinin cesitli degiskenlere gore incelenmesidir. Calismada verilerin toplanmasi amaciyla “Teknoloji Kabul Olcegi” ve “Teknostres Olcegi” kullanilmistir. Calisma bir devlet universitesinde gorev yapmakta olan ve farkli akademik programlarda gorev yapan toplam 180 ogretim elemani ile gerceklestirilmistir. Verilerin cozumlenmesinde betimsel istatistikler, bagimsiz orneklem t-testi, tek-yonlu ANOVA testi ve degiskenler arasindaki iliskinin incelenmesi amaciyla ise Pearson korelasyon analizi kullanilmistir. Arastirmada ogretim elemanlarinin bilgi ve iletisim teknolojilerine yonelik kabullerinin yuksege yakin oldugu gorulurken, teknostres algilarinin ise orta duzeyde oldugu belirlenmistir. Bununla birlikte ogretim elemanlarinin bilgi ve iletisim teknolojilerine yonelik kabulu ve teknostres algilari ile cinsiyet, yas, uzmanlik alani ve gunluk ortalama internet kullanim suresi degiskenleri arasinda anlamli farklilik bulunmustur. Calismada ayrica, elde edilen bulgular ogretim elemanlarinin bilgi ve iletisim teknolojilerine yonelik kabulleri ve teknostres algilari arasinda negatif yonde ve orta duzeyde bir iliski oldugunu ortaya koymustur.
Glycemic Control, Serum Leptin and Lipid Profile in Patients With Pulmonary Tuberculosis: Effect of Initial Two Months Anti-Tuberculosis Therapy

Objectives:To evaluate the effect of pulmonary tuberculosis (TB) on glycemic control (fasting serum glucose "FSG", serum insulin, C-peptide and insulin resistance), serum leptin and lipid profile (total cholesterol 'Tc', triglyceride "TG", low density lipoprotein cholesterol "LDL-C", high density lipoprotein cholesterol "HDL-C" and atherogenic index AI) and to evaluate the effects of intensive 2-months anti-tuberculosis therapy on these parameters in comparison to healthy controls. Methods:Forty three patients with active pulmonary tuberculosis from the Advisory Clinic for Chest and Pulmonary Diseases in Mosul City were included in this study, with 40 apparently healthy age and sex matched subjects as controls. Assessment of serum concentration of FSG, C-peptide, serum insulin levels and insulin resistance, with serum leptin and lipid profile were done for the patients and controls. After two months with intensive anti- TB therapy (isoniozid "INH" 75 mg, rifampicin 150mg, pyrazinamide 400mg and ethambutol 275mg) 4 tablets as a single dose in the morning with vitamin B6 10mg daily, the same parameters were reassessed for the patients. Body mass index were calculated for both the patients and control using especial equation. Results:With the exception of body mass index (BMI), there was insignificant differences with regard the parameters of glycemic control, serum leptin and parameters of lipid profile between newly diagnosed patients with pulmonary TB in the pre-therapy stage and healthy controls. After 2 months of therapy, there was a significant increase in BMI, serum leptin and serum TG with insignificant differences in the other parameters under study.Conclusion: In this study active pulmonary TB as a disease did not affect parameters that represent glycemic controls, serum leptin and lipid profile. Intensive 2-months therapy with anti-TB drugs brings about a significant increase in BMI, serum leptin and TG with insignificant effect on glycemic control, and other parameters of lipid profile.
Source Domain Verification Using Corpus-based Tools

ABSTRACT Source domain verification has not received as much attention as criteria for metaphor identification in the study of conceptual metaphor. In this paper, we provide a replicable approach to source domain verification which we hope will provide a foundation for new approaches to this important question. We adopt an empirical method extended from previous research that used corpus-based linguistic tools such as SUMO (Suggested Upper Merged Ontology), WordNet, collocational patterns and an online dictionary. We present a new, step-by-step procedure to verify which keywords may be categorized in the source domain of building, using data from the Corpus of Hong Kong Political Speeches which contains parsed Chinese-language speeches by Hong Kong Chief Executives of the Hong Kong Special Administrative Region (1997–2014). Following the verification of a number of keywords in the building source domain, we discuss how this method may be adapted for other source domains and languages and discuss its application to various areas of study within metaphor research as well as the current limitations of this approach.
Faktor yang Berhubungan Terhadap Kejadian Partus Lama di Rumah Sakit AL Jala Ammari Makassar 2019

Berdasarkan data yang diperoleh dari hasil pencatatan dan pelaporan Rumah Sakit Angkatan Laut Jala Ammari Makassar menyatakan bahwa jumlah persalinan pada tahun 2017 periode Januari-Desember sebanyak 1.108, Pada tahun 2018 periode Januari-Desember sebanyak 1.258, Sedangkan pada tahun 2019 periode Januari-April sebanyak 76 orang. Tujuan dilakukan penelitian ini adalah untuk mengetahui hubungan antara Usia Ibu, Posis Janin, Berat Badan Bayi Lahir dan Paritas terhadap kejadian partus lama di Rumah Sakit AL Jala Ammari Makassar Januari – April 2019. Penelitian ini menggunakan metode penelitian dengan menggunakan pendekatan Cross Sectional Study untuk mengetahui hubungan antara usia ibu dan posisi janin terhadap kejadian partus lama Di Rumah Sakit AL Jala Ammari Makassar dengan jumlah populasi sebanyak 76 orang dengan menggunakan teknik total sampling. Dari hasil uji statistic dengan menggunakan uji Chi-Square (pearson chi-square) diperoleh untuk variabel usia ibu nilai p = 0,000 α = 0,05 artinya ada hubungan antara berat bayi lahir dengan kejadian partus lama. Untuk variabel hubungan paritas dengan kejadian partus lama nilai P (0,000) > α = 0,05 artinya ada hubungan antara paritas dengan kejadian partus lama.
Eyelid malpositions: An overview

Eyelid malpositions are the result of forces acting upon the eyelid margin. A normal eyelid should have a quick return snap to the eyeball. Frequently, tendon laxity at the medial and lateral canthi will render the eyelid margin unstable making it susceptible to contractile forces. Based on the contractile forces either entropion, ectropion, retraction or lagophthalmos can occur. The goal in treating a given eyelid malposition is to reposition the eyelid so that the new healing forces will overcome the pathologic forces. The common approaches include eyelid and canthal tendon tightening, eyelid retractor advancement or recession and skin grafting or transposition flaps. This review article briefly describes the various aspects of lid malpositions in detail.
Review—Non-Invasive Monitoring of Human Health by Exhaled Breath Analysis: A Comprehensive Review

Exhaled human breath analysis is a very promising ﬁ eld of research work having great potential for diagnosis of diseases in non- invasive way. Breath analysis has attracted huge attention in the ﬁ eld of medical diagnosis and disease monitoring in the last two decades. VOCs/gases (Volatile Organic Compounds) in exhaled breath bear the ﬁ nger-prints of metabolic and biophysical processes going on in human body. It ’ s a non-invasive, fast, non-hazardous, cost effective, and point of care process for disease state monitoring and environmental exposure assessment in human beings. Some VOCs/gases in exhaled breath are bio-markers of different diseases and their presence in excess amount is indicative of un-healthiness. Breath analysis has the potential for early detection of diseases. However, it is still underused and commercial device is yet not available owing to multiferrious challenges. This review is intended to provide an overview of major biomarkers (VOCs/gases) present in exhaled breath, importance of their analysis towards disease monitoring, analytical techniques involved, promising materials for breath analysis etc. Finally, related challenges and limitations along with future scope will be touched upon. for acute decompensated heart failure), Alkhouri et al. (biomarker identi ﬁ ed: acetone, isoprene, trimethylamine, acetaldehyde, pentane for non-alcoholic fatty liver disease), Hanouneh et al. (biomarker identi ﬁ ed: 2-propanol, ethanol, acetone, trimethylamine, acetaldehyde, pentane for alcoholic hepatitis), Walton et al. (biomarker identi ﬁ ed: acetone for diabetes mellitus), Storer et al. (biomarker identi ﬁ ed: acetone for diabetes mellitus) process, high energy sites available in quantum dots, nanorods, nano sheets, nano tubes, nano belts and other exotic nanostructures, doping of novel and non-novel metals and oxides
EMPODERAMENTO E COMPETÊNCIAS INDIVIDUAIS E GRUPAIS: a criação de ambiente organizacional favorável à inovação

This article seeks to understand how some assumptions underlying Empowerment, such as Self-development, Reflective Practice and Experiential Learning, identified from a theoretical framework, can be positive to the process of developing individual and group competencies from the point of view of Creation of an organizational environment favorable to innovation. Methodologically, the present study can be classified as a descriptive exploratory analysis by means of a singular case study and qualitative nature. The technique of data collection was through personal interviews, use of a semi-structured questionnaire and non-participant observation. The semi-structured questionnaire was composed of open questions, previously selected, whose answers took shape from the interviewee's point of view. The main objective of the observations was to analyze the processes of Self-development, Experiential Learning and
Energy efficiency in CMOS power amplifier designs for ultralow power mobile wireless communication systems

: Wireless communication standards keep evolving so that the requirement for high data rate operation can be fulfilled. This leads to the efforts in designing high linearity and low power consumption radio frequency power amplifier (RFPA) to support high data rate signal transmission and preserving battery life. The percentage of the DC power of the transceiver utilized by the power amplifier (PA) depends on the efficiency of the PA, user data rate, propagation conditions, signal modulations, and communication protocols. For example, the PA of a WLAN transceiver consumes 49% of the overall efficiency from the transmitter. Hence, operating the PA with minimum power consumption without trading-off the linearity is vital in order to achieve the goal of fully integrated system-on-chip (SoC) solution for 4G and 5G transceivers. In this paper, the efficiency in CMOS PA is discussed through the review of multifarious efficiency enhancement techniques in CMOS PA design. This is categorized into the review of efficiency in fundamental classes of PA in which Class E achieves the highest efficiency of 67%, followed by complex architectures utilized to enhance the efficiency level of the PA in which the outphasing architecture achieved the highest efficiency of 60.7%
A Pilot Randomized Controlled Trial to Promote Physical Activity and Change Fitness Scores in Rural College Students: The Northern eHealth / mHealth Trial (N-EMT)

The aim of this study was to examine the feasibility and efficacy of two different technology-based health education interventions on physical activity (PA) and physical fitness (PF) outcomes in college students. A total of N=15 college students attending a small rural university were equally randomized to one of three groups: eHealth, mHealth, or wait-list control. Intervention components lasted four weeks. The eHealth group received four 1-week long health education modules via a campus-based website. The mHealth group also received four 1-week long modules with similar content as eHealth but with use of instant messaging and Facebook alerts. The control group was asked to behave in their usual manner. Outcome measures included scores from PF assessments, self-reported PA, theory of planned behavior (TPB) scales, and health-related quality of life (HRQOL) measures. Analyses indicated that mHealth made improvement on all PF measures. As well, mHealth made more improvement on PA measures than either eHealth or control. Results from this pilot study indicate that technology-based health education interventions are a feasible and efficacious strategy for promoting PA on rural college campuses.
Exercise for Falls Prevention: Decision-making among Australian-born and Italian-born Older People

ABSTRACT In this article, we examine factors contributing to decision-making in regards to participation and adherence to exercise to reduce falls by older people with recent falls history. Nineteen participants (9 Australian-born and 10 Italian-born; median age 78 years) who had ≥1 fall in the past 12 months and completed a community based physiotherapy program were recruited. Semi-structured interviews were conducted, transcribed, and thematically analyzed. The findings show that family, client-clinician relationship and personal experience affected decision-making and exercise participation. The findings revealed that a number of factors influenced older people’s decision and uptake of falls prevention exercise, including personal goals, recommendations from health care providers, and life experiences. There were some differences between the Italian-born and the Australian-born participants, including that most Australian-born participants adhere to exercise programs in order to avoid requiring nursing home care, whereas Italian-born individuals did not wish to be dependent on their children. An understanding of personal motivating and de-motivating factors for exercise for falls prevention are important for health and social care professionals to consider in engaging some groups of older people.