Miracle-dz/UniFAR-FTUs huggingface dataset:
Glycated hemoglobin and diabetes: a case and an overview of the subject.

"his case focuses on the measurement of glycatad heme globin in a patient with diabetes mellitus. We then diecusa the biochemistay of glycatad proteins, in particular globin, the methods of meaeuring glycatad hemoglobin, ita clinical application, and ita relationship to the complications of diabetes mellitus. Pmntatlon of the Case
Illusion of Parallelism in Reduced Illumination

A picture-plane theory of the illusion of parallelism was tested by replicating, with only standard and variable dimly visible, portions of a previous study demonstrating positive and negative directions of the illusion. The differences between means of the two studies ranged from 0.2° to 11.6°. Correlation between the matrices of the two studies was +. 62, indicative of common determinants, one of which was proposed to be the aptitude of spatial visualization. The picture-plane theory remained tenable.
Primary Total Hip Arthroplasty with a Second-Generation Cementless Total Hip Prosthesis in Patients Younger Than Fifty Years of Age

Background: The early experience with cementless total hip replacement led to design modifications to increase the initial press-fit and stability of the femoral component, to reduce the diameter of the femoral head, and to improve the acetabular component, including the locking mechanism of the shell and the quality of the polyethylene liner. We performed a prospective study to assess the results in young patients who had been followed for a minimum of eight years after treatment with a primary total hip arthroplasty with a second-generation cementless prosthesis.Methods: Eighty patients (118 hips) were included in the study. There were fifty-eight men and twenty-two women; the mean age at the time of the operation was 46.8 years (range, twenty-one to forty-nine years). We used a cementless Duraloc series-100 or 1200 acetabular component with or without screw fixation, a polyethylene liner with a 22-mm inner diameter, and a cementless Profile femoral component in all hips. The average duration of follow-up was 9.8 years (range, eight to eleven years). Clinical follow-up (with use of the Harris hip score) and radiographic follow-up were performed at six weeks; at three, six, and twelve months; and yearly thereafter. Linear and volumetric wear were measured, and bone-remodeling and osteolysis were assessed.Results: The average Harris hip score improved from 48.8 points preoperatively to 92 points at the final follow-up examination. The prevalence of transitory thigh pain was 10% (twelve of 118 hips). There was no aseptic loosening. One hip was revised because of recurrent dislocation. The average amount of linear wear was 1.18 mm, and the average wear rate was 0.12 mm/yr. Fourteen hips (12%) had osteolysis in the calcar femorale and eleven hips (9%) had acetabular osteolysis, but all of the osteolytic lesions were <1 cm 2.Conclusions: The mechanical fixation of the anatomic fit cementless Profile stem was excellent in this study of young patients who were particularly difficult to treat because of a high prevalence of osteonecrosis and developmental dysplasia. Although there was no aseptic loosening of the components and a relatively low prevalence of osteolysis, there was a high rate of linear wear of the polyethylene liner.Level of Evidence: Therapeutic study, Level IV (case series [no, or historical, control group]). See p. 2 for complete description of levels of evidence.
The Importance of Internet of Things Security for Smart Cities

The purpose of this chapter is to provide an extensive overview of security-related problems in the context of smart cities. The impressive heterogeneity, ubiquity, miniaturization, autonomous and unpredictable behaviour of objects interconnected in Internet of Things, the real data deluges generated by them and, on the other side, the new hacking methods based on sensors and short-range communication technologies transform smart cities in complex environments in which the already-existing security analyses are not useful anymore. Specific security vulnerabilities, threats and solutions are approached from different areas of the smart cities' infrastructure. As urban management should pay close attention to security and privacy protection, network protocols, identity management, standardization, trusted architecture, etc., this chapter will serve them as a start point for better decisions in security design and management.
Business rules, decisions and processes: five reflections upon living apart together

Information Systems must provide flexible support for business processes, which should be compliant to the (intra-organizational) business policies and procedures, to regulations and to imposed protocols. Some separation of concerns, i.e. making the imposed constraints explicit, has been observed in order to comply with this dual objective of flexibility and compliance. In this paper, a list of five reflections is used to examine the coexistence and the relationship between business rules, decisions and processes. These considerations will be useful when evaluating how to become less dependent on rigid process models containing large parts of business and decision logic.
A survey on how students seek information on the internet

Navigating among the information available on the Internet has become an expectation for the members of the information society we are living in. This especially applies to students of higher education, the intellectuals of the future. It is a general experience that most users make one or two word searches and they don’t know about the possibilities offered by various search engines, which can make searches more effective. Given results from abroad we have set up a study among the students of the University of Debrecen (UD) about their use of the Internet, their knowledge of searching strategies and techniques, their perceptions of the effectiveness and efficiency of search engines. This paper reports the results of this study. The results imply that it is imperative that area should be included in the curriculum.
Managing Social Knowledge Management: Balancing the Gatekeeping vs. Crowdsourcing Requirements

In a knowledge driven economy, the ability of a firm to grow and gain competitive advantage is defined by its ability to realize economic value from its knowledge assets. In one form or the other, firms have attempted to capitalize on the power of knowledge based economy. Multiple steps were taken by various firms to capture the knowledge and create knowledge bank in form of KM tools and other propriety media. Social media has provided firms with a very powerful tool to appropriate the benefits of such codified knowledge. Social media, in form of both public social network sites and propriety social media tools has enabled collaborative creation and storage of knowledge like never before in human history. Availability of these media has lowered the barrier of entry in a knowledge driven economy by democratizing collection and organization of knowledge. In this chapter, we present an exploratory framework to analyze the implications of use of various types of social media based KM tools on the firm’s knowledge collection and sharing strategies.
Improving the Reproducibility of P3HT:PCBM Solar Cells by Controlling the PCBM/Cathode Interface

Plastic photovoltaic devices offer a real potential for making solar energy economically viable. Unfortunately, bulk heterojunction (BHJ) solar cells fabricated from blends of the commonly used materials poly(3-hexylthiophene), P3HT, and phenyl-C61-butyric acid methyl ester, PCBM, sometimes exhibit low efficiencies even when the procedures followed often produce solar cells with efficiencies exceeding 5%. In this Letter, we show that this irreproducibility is caused by subtleties in the film processing conditions that ultimately lead to poor electron extraction from the devices. For low-performing devices, photogeneration and charge extraction with a linearly increasing voltage ramp (photo−CELIV) measurements show an order-of-magnitude difference in the effective mobilities of the electrons and holes. Atomic force microscopy (AFM) experiments reveal that the top surface of these low-performing devices is nearly pure P3HT. We argue that small variations in the solvent evaporation kinetics during spin-coati.
Core self-evaluations and Snyder's hope theory in persons with spinal cord injuries.

OBJECTIVE The objective of the study was to evaluate a motivational model of core self-evaluations (CSE), hope (agency and pathways thinking), participation, and life satisfaction in persons with spinal cord injuries. DESIGN A cross-sectional, correlational design with path analysis was used to evaluate the model. PARTICIPANTS 187 adults with spinal cord injuries participated in this study. RESULTS The results indicated an excellent fit between the data and the proposed model. Specifically, CSE was found to directly predict agency and pathways thinking, participation, and life satisfaction. CSE was also found to indirectly predict participation and life satisfaction through agency thinking. CONCLUSIONS Although CSE contributes directly to participation and life satisfaction, it also has a unique role in increasing individuals' motivation to pursue goals, which also predicts participation and life satisfaction. Counseling interventions should be multifaceted and address the components of CSE to increase hope, participation, and life satisfaction.
The Level of IgE Produced by a B Cell Is Regulated by Norepinephrine in a p38 MAPK- and CD23-Dependent Manner1

Although the causes of asthma vary, the severity of the disease correlates with the level of IgE produced. In this study we show that mice produced less IgE when they were depleted of the neurotransmitter norepinephrine (NE) before the administration of Ag. The suppression was prevented when a β2-adrenergic receptor (β2AR)-selective agonist was administered, suggesting that NE stimulated the β2AR to regulate the level of an IgE response in vivo. Although the cell targeted by NE to produce this effect in vivo is unknown, we show in vitro that the level of IgE increased on a per cell basis without an effect on class switch recombination when NE stimulated the β2AR on a B cell directly. The β2AR-induced increase in IgE depended on p38 MAPK but not protein kinase A activation, was due to an increased rate of mature IgE mRNA transcription, and was lost when β2AR-deficient B cells were used. Also, CD23 transcription was increased in a p38 MAPK-dependent manner and resulted in an increased level of soluble CD23 (sCD23). The β2AR-induced increase in sCD23 was associated with IgE up-regulation and possibly interacted with CD21/CD19. Using B cells from respective knockout mice, data showed that the β2AR-induced increase in IgE depended on B cell expression of CD23, CD21, and CD19. These findings suggest that at least one mechanism by which endogenous B cell activity in vivo is regulated by NE involves stimulation of the β2AR on the B cell alone to increase the level of IgE produced in a p38 MAPK- and sCD23-dependent manner.
Exploring Wikipedia and Query Log's Ability for Text Feature Representation

The rapid increase of Internet technology requires a better management of Web page contents. Many text mining researches has been conducted, like text categorization, information retrieval, text clustering. When machine learning methods or statistical models are applied to such a large scale of data, the first step we have to solve is to represent a text document into the way that computers could handle. Traditionally, single words are always employed as features in vector space model, which make up the feature space for all text documents. The single-word based representation is based on the word independence and doesn't consider their relations, which may cause information missing. This paper proposes Wiki-Query segmented features to text classification, in hopes of better using the text information. The experiment results show that a much better F1 value has been achieved than that of classical single-word based text representation. This means that Wikipedia and query segmented feature could better represent a text document.
High Ratio of Bacteriochlorophyll Biosynthesis Genes to Chlorophyll Biosynthesis Genes in Bacteria of Humic Lakes

ABSTRACT Recent studies highlight the diversity and significance of marine phototrophic microorganisms such as picocyanobacteria, phototrophic picoeukaryotes, and bacteriochlorophyll- and rhodopsin-holding phototrophic bacteria. To assess if freshwater ecosystems also harbor similar phototroph diversity, genes involved in the biosynthesis of bacteriochlorophyll and chlorophyll were targeted to explore oxygenic and aerobic anoxygenic phototroph composition in a wide range of lakes. Partial dark-operative protochlorophyllide oxidoreductase (DPOR) and chlorophyllide oxidoreductase (COR) genes in bacteria of seven lakes with contrasting trophic statuses were PCR amplified, cloned, and sequenced. Out of 61 sequences encoding the L subunit of DPOR (L-DPOR), 22 clustered with aerobic anoxygenic photosynthetic bacteria, whereas 39 L-DPOR sequences related to oxygenic phototrophs, like cyanobacteria, were observed. Phylogenetic analysis revealed clear separation of these freshwater L-DPOR genes as well as 11 COR gene sequences from their marine counterparts. Terminal restriction fragment length analysis of L-DPOR genes was used to characterize oxygenic aerobic and anoxygenic photosynthesizing populations in 20 lakes differing in physical and chemical characteristics. Significant differences in L-DPOR community composition were observed between dystrophic lakes and all other systems, where a higher proportion of genes affiliated with aerobic anoxygenic photosynthetic bacteria was observed than in other systems. Our results reveal a significant diversity of phototrophic microorganisms in lakes and suggest niche partitioning of oxygenic and aerobic anoxygenic phototrophs in these systems in response to trophic status and coupled differences in light regime.
Making the grade in public health advocacy.

We are pleased that public health advocacy was the theme of the August 2003 issue of the Journal. However, we find that several areas need further emphasis. As noted by Avery and Bashir, speaking truth to power is a right and “the advocate takes this right and makes it her duty. ”1(pp1208, 1209) All public health professionals should be engaged in public policy reform. Yet the draft of the Public Health Professional’s Oath promulgated by APHA (and absent from this issue) speaks too softly and says too little on public health professionals’ responsibility to engage in policy and social change.2 We also value the inclusion of Minkler and colleagues’ article on community-based participatory research (CBPR),3 given the essential need for political acumen in CBPR. Indeed, the Institute of Medicine identified CBPR, as well as policy and law, among the 8 areas to be strengthened in graduate public health training.4 The authors added, “Although the importance of policy in public health has long been recognized . , education in policy at many schools of public health is currently minimal. Should schools wish to be significant players in the future of public health and health care, dwelling on the science of public health without paying appropriate attention to both politics and policy will not be enough. ”4(p 13) Advocacy has been listed among health education competencies since the mid-1980s and is on the emerging list of competencies for all public health professionals.5,6 APHA’s Public Health Education and Health Promotion (PHEHP) Section has cosponsored 6 health education advocacy summits with the Coalition of National Health Education Organizations. PHEHP also has participated in developing a Web site to disseminate advocacy information and resources.7,8 We have seen little progress in students’ professional preparation as public health advocates in our years providing Capitol Hill experience to nearly 500 students and health education professionals since 1998. APHA, public health schools and programs, and others engaged in public health workforce development must place a higher priority on offering meaningful courses and continuing education in policy and media advocacy. As the Institute of Medicine underscores, it is time for our schools and programs to appreciate all the dimensions of our role as public health professionals and to reward faculty for advocacy involvement. It is also time for journal editors, authors, and researchers to fully embrace the importance of their work in the advocacy arena.
3D body shape clustering based on PSO by multi-fitness function

Human body shape plays an important role in many industries, especially in Healthcare. We have seen changes in the body size and shape of the Thai population from the data collected through national sizing surveys over two decades. These changes can also indicate the trend of national health status. In this paper, a body shape clustering algorithm based on particle swarm optimization with multi fitness function is proposed. It improves accuracy and efficiency of our previous work. This proposed method consists of four parts. First, the body plane detection to identify the front and the back of the body is defined by the Eigenvector and Eigenvalue. Second, the derivative of edges of body technique is used to detect body landmarks whereby body measurements are taken. Third, the identification of the body size according to the Thai Women's sizing system performed using three main body dimensions which consist of bust, waist and hip girths. Finally, a multi-fitness function, a combination of the volumetric overlap function and the euclidean distance of body measurements ratios, is used to calculate a similarity value between 2 body data. In the final step, PSO is used to group body shapes according to each body size. Results are then compared with those obtained from k-means clustering and the identified shapes from the Female Figure Identification Technique (FFIT). The results show that our PSO clustering can dynamically group people with similar body shapes and, at the same time, avoid those that are dissimilar. This algorithm can be extend work with larger population.
H2oT: HTTP/2 for the Internet of Things

This document makes the case for HTTP/2 for IoT. Status of This Memo This Internet-Draft is submitted in full conformance with the provisions of BCP 78 and BCP 79 . Internet-Drafts are working documents of the Internet Engineering Task Force (IETF). Note that other groups may also distribute working documents as Internet-Drafts. The list of current InternetDrafts is at http://datatracker.ietf. org/drafts/current/ . Internet-Drafts are draft documents valid for a maximum of six months and may be updated, replaced, or obsoleted by other documents at any time. It is inappropriate to use Internet-Drafts as reference material or to cite them other than as "work in progress. " This Internet-Draft will expire on January 9, 2017. Copyright Notice Copyright (c) 2016 IETF Trust and the persons identified as the document authors. All rights reserved. This document is subject to BCP 78 and the IETF Trust’s Legal Provisions Relating to IETF Documents ( http://trustee.ietf.org/license-info ) in effect on the date of publication of this document. Please review these documents carefully, as they describe your rights and restrictions with respect to this document. Code Components extracted from this document must include Simplified BSD License text as described in Section 4 . e of Montenegro, et al. Expires January 9, 2017 [Page 1] Internet-Draft H2oT July 2016 the Trust Legal Provisions and are provided without warranty as described in the Simplified BSD License. Table of
Etoposide with lonidamine or pentoxifylline as modulators of alkylating agent activity in vivo

In an effort to improve the additive anti‐tumor efficacy of commonly used alkylating agents, the topoisomerase‐II inhibitor etoposide was used in combination with either the mitochondrial poison and energy‐depleting agent lonidamine or the hemorheologic agent and tumor‐blood‐flow‐increasing agent pentoxifylline. In the FSallC murine fibrosarcoma system, these modulators were evaluated for modulation of whole‐tumor cell killing vs. bone‐marrow CFU‐GM toxicity with the alkylating drugs CDDP, CTX, L‐PAM or BCNU. Etoposide alone was essentially additive with the alkylating drugs for both tumor‐cell and bone‐marrow killing, except for BCNU, where a substantial increase in tumor‐cell killing occurred (0.5 to 2.0 logs over the dose range of BCNU tested) without a significant increase in bone‐marrow toxicity. Etoposide plus lonidamine was significantly more active than etoposide alone only with CTX and BCNU in tumor‐cell vs. bone‐marrow killing. Etoposide plus pentoxifylline was also most active with these two alkylating agents, where increases in tumor‐cell killing of 0.5 to 1.0 log were observed. Hoechst‐33342‐defined tumor‐cell sub‐population studies revealed that etoposide significantly improved the killing of dim (putative hypoxic) cells by CDDP, but neither lonidamine nor pentoxifylline significantly improved killing of bright or dim cells together. With CTX, etoposide plus lonidamine or pentoxifylline substantially improved killing of dim cells over etoposide alone (each by about 0.8 logs). These data indicate that a therapeutic advantage may be achievable by combining etoposide with lonidamine or pentoxifylline for use with alkylating drugs.
Trait Variation in Yeast Is Defined by Population History

A fundamental goal in biology is to achieve a mechanistic understanding of how and to what extent ecological variation imposes selection for distinct traits and favors the fixation of specific genetic variants. Key to such an understanding is the detailed mapping of the natural genomic and phenomic space and a bridging of the gap that separates these worlds. Here we chart a high-resolution map of natural trait variation in one of the most important genetic model organisms, the budding yeast Saccharomyces cerevisiae, and its closest wild relatives and trace the genetic basis and timing of major phenotype changing events in its recent history. We show that natural trait variation in S. cerevisiae exceeds that of its relatives, despite limited genetic variation, and follows the population history rather than the source environment. In particular, the West African population is phenotypically unique, with an extreme abundance of low-performance alleles, notably a premature translational termination signal in GAL3 that cause inability to utilize galactose. Our observations suggest that many S. cerevisiae traits may be the consequence of genetic drift rather than selection, in line with the assumption that natural yeast lineages are remnants of recent population bottlenecks. Disconcertingly, the universal type strain S288C was found to be highly atypical, highlighting the danger of extrapolating gene-trait connections obtained in mosaic, lab-domesticated lineages to the species as a whole. Overall, this study represents a step towards an in-depth understanding of the causal relationship between co-variation in ecology, selection pressure, natural traits, molecular mechanism, and alleles in a key model organism.