Miracle-dz/UniFAR-FTUs huggingface dataset:
Isothermal PCR for Feasible Molecular Diagnosis of Primary Toxoplasmosis in Women Recently Experienced Spontaneous Abortion

AIM: The current study aimed to assess the practicability of a simple loop-mediated isothermal amplification (LAMP) about real-time quantitative PCR to diagnose primary toxoplasmosis among high-risk pregnant women. METHODS: Cloned Toxoplasma samples were used to calculate the analytical sensitivity while specificity was assessed using pooled DNA samples extracted from other parasitic stages. RESULTS: Both techniques showed 100% sensitivity and specificity and then applied to detect recent Toxoplasma infection in peripheral blood of 77 IgG negative women out of a total 139 women lately experienced spontaneous abortion. The 2 techniques obtained positive results in 8 samples confirming primary toxoplasmosis. CONCLUSION: Generally, LAMP assay is a simple, cost-effective molecular technique can be completed in less than half an hour to diagnose primary Toxoplasma infection. The technique can be applied in a minimally equipped laboratory by ordinary workers to screen the vulnerable groups. Further analysis using larger samples with the quantitative approach is recommended to confirm the sensitivity of this emergent molecular technique.
The diversity of temporal niches in mammals

The division of animals into those that are diurnal (day-active) and those that are nocturnal (night-active) is widely recognized. However, closer examination of the selection of temporal niches by mammalian species reveals the existence of a gradient of diurnality between and within species, wherein “diurnal” and “nocturnal” are merely the opposite ends of a continuum. Evidence against a simple diurnal – nocturnal dichotomy includes the existence of species without any preference for time of day, species with a crepuscular pattern of activity, species containing both diurnal and nocturnal individuals, species containing individuals that spontaneously shift from a nocturnal to a diurnal activity pattern, species showing degrees of diurnality greater or smaller than those of other species, organismal variables exhibiting degrees of diurnality greater or smaller than those of other variables, and species having different temporal patterns under the effects of different environmental variables. Research on the neural processes responsible for temporal niche selection has revealed no fundamental difference between the circadian clocks of diurnal and nocturnal animals, but recent findings suggest that different output pathways from the clock in a given species may operate with different circadian phases, thus providing an explanation for why different body functions in the same individual are subjected to different temporal niche selections.
Genome Sequence of Torulaspora microellipsoides CLIB 830T

We report here the genome sequence of the ascomycetous yeast Torulaspora microellipsoides CLIB 830T. A reference genome for this species, which has been found as a donor of genetic material in wine strains of Saccharomyces cerevisiae, will undoubtedly give clues to our understanding of horizontal transfer mechanisms between species in the wine environment. ABSTRACT We report here the genome sequence of the ascomycetous yeast Torulaspora microellipsoides CLIB 830T. A reference genome for this species, which has been found as a donor of genetic material in wine strains of Saccharomyces cerevisiae, will undoubtedly give clues to our understanding of horizontal transfer mechanisms between species in the wine environment.
Effects of Food Habits and Lifestyle on Prevalence of Overweight/Obesity among Schoolchildren in Taif Area, KSA

Background/Objectives: The Saudi population has experienced significant transformations in their lifestyle which could be attributed to several factors. Aims: This work sought to determine effects of food habits and lifestyle on prevalence of overweight (OW)/obesity (OB) among schoolchildren in Taif City, KSA. Materials and Methods: A cross-sectional study was carried out using well-designed questionnaire. Pretested questionnaire was randomly distributed among schoolchildren in Taif city. Body mass index and waist circumference were used as tools for assessing nutritional status of schoolchildren. Results: A total of 2027 students filled the questionnaire with a mean age of 15.83 ± 2.18 years. The prevalence of OW and OB was 14.6% and 12.9%, respectively, while the combined one was 27.5%. The combined prevalence of OW and OB was significantly higher among boys than girls (31.9 vs. 21.9). Schoolchildren from high income families had high rate of OW and OB. Smoking, stress, TV viewing, daylight and night sleep had no effects on BMI, while only smoking of a family member and stress had considerable relationship with W_C. Unfortunately, 52.2% of students admitted that they were physically inactive but this effect was insignificant for both indicators. Students skipped breakfasts constitute 18.8% of subjects included but link with BMI and W_C was statistically insignificant. Regular soft or diet drinks had significant effects on BMI. Results showed considerable link between consumption of fruits/vegetables, grains and W_C. Conclusions: The prevalence of combined OW/OB among schoolchildren was 27.5%. Family income, participant’s gender, intake of regular soft or diet drinks had significant effects on BMI. While, stress, smoking of a family member, and uptake of fruits and vegetables showed considerable relationship with W_C.
Clinician-delivered cognitive training for children with attention problems: effects on cognition and behavior from the ThinkRx randomized controlled trial

Purpose The impact of attention problems on academic and social functioning coupled with the large number of children failing to respond to stimulant medication or behavioral therapy makes adjunctive therapies such as cognitive training appealing for families and clinicians of children with attention difficulties or childhood attention deficit hyperactivity disorder. However, the results of cognitive training studies have failed to find far transfer effects with this population. This study examined the quantitative cognitive effects and parent-reported behavioral effects of a clinician-delivered cognitive training program with children who have attention problems. Patients and methods Using a randomized controlled study design, we examined the impact of a clinician-delivered cognitive training program on processing speed, fluid reasoning, memory, visual processing, auditory processing, attention, overall intelligence quotient score, and behavior of students (n=13) aged 8–14 years with attention problems. Participants were randomly assigned to either a waitlist control group or a treatment group for 60 hours of cognitive training with ThinkRx, a clinician-delivered intervention that targets multiple cognitive skills with game-like, but rigorous mental tasks in 60–90-minute training sessions at least 3 days per week. Results Results included greater mean pretest to posttest change scores on all variables for the treatment group versus the control group with statistically significant differences noted in working memory, long-term memory, logic and reasoning, auditory processing, and intelligence quotient score. Qualitative outcomes included parent-reported changes in confidence, cooperation, and self-discipline. Conclusion Children with attention problems who completed 60 hours of clinician-delivered ThinkRx cognitive training realized both cognitive and behavioral improvements.
Hypertension and its Correlates in the Oldest Old Population Aged 80 Years and Above in Urban South India

Background Hypertension is a major problem among the geriatric population, presenting the risk of multiple associated co-morbidities and organ system damage. Data related to the epidemiology of controlled and uncontrolled hypertension among the oldest old population is sparse, more so from developing countries. The objectives of the present paper were to identify the prevalence and correlates of hypertension according to gender among the urban community-dwelling healthy oldest old population. Methods 200 healthy people aged 80 years and above were recruited by random selection from Hyderabad city of South India in 2017. A trained investigator collected data on background history, history of hypertension and other co-morbidities, medications and sleep. Participants were tested for muscle strength, gait speed, and SPPB and cognitive impairment. Results The prevalence of hypertension was 83.5%; 81.6% among men and 84.7% among women. 64.5% was self-reported. Hypertension was controlled with treatment among only 46.2%. In 74.6%, it was controlled even without treatment. The independent correlates were BMI per SD increase (OR: 1.92, 95% CI: 1.17–3.16), diabetes (OR: 6.02, 95% CI: 1.24–29.11) and asthma (OR: 3.59, 95% CI: 1.05–12.29). Among men, BMI per SD increase was significantly associated while hemoglobin per SD increase, height per SD decrease, and arthritis were positively associated among women. Increasing heart rate among total subjects (OR: 0.44, 95% CI: 0.27–0.71), and among women (OR: 0.47, 95% CI: 0.24–0.92) showed a negative association. Conclusion The prevalence of hypertension was high. The correlates were different for men and women. Subjects were unaware of their control status which posed an increased risk for organ damage, and development of co-morbidities. Policies aimed at improving quality of life of the oldest old should place due stress on appropriate hypertension management in developing countries.
Ultrasonic strain wave acquisition by a low-cost fiber optic coherent sensor for structural health monitoring applications

Optical fiber sensors (OFSs) have been recently used for impact monitoring, impact force reconstruction, Lamb wave monitoring and acoustic emission monitoring. In particular, most of the studies available in the structural health monitoring (SHM) literature perform local measurements by means of fiber Bragg gratings, which provide high signal to noise ratios but are associated to expensive acquisition systems, making the scalability of this diagnostic solution not sustainable for realistic structure monitoring. Optical fiber interferometers have been also exploited for acoustic and ultrasonic sensing, although one main drawback of interferometric OFS is that the entire length of the leading optical fiber is sensitive, while punctual measurements are desirable in many SHM applications. A cost-effective solution for ultrasonic wave monitoring is proposed in this paper for high frequency SHM applications. The sensor relies on a fiber optic Michelson interferometric architecture associated to an innovative coherent detection scheme, which retrieves in a completely passive way the phase information of the received optical signal. The optical fiber is organized into multiple loop structures glued on an aluminum thin panel in order to increase the phase signal relative only to the sensing points of interest. The ultrasonic wave emitted by a piezoelectric transducer placed on the aluminium panel is then acquired by the coherent FOS with different sensor layouts as a function of the number of sensor fiber loops and the fiber gage length. Measurements carried out with the coherent fiber optic sensor are then compared with traditional piezoelectric sensors. The proposed fiber-optic solution represents a promising, cost-effective and highly sensitive measurement technique for impact monitoring, including both passive impact identification (detection, localization and energy estimation) and active damage monitoring, e.g. by means of Lamb wave scatter analysis.
What Design Topics do Developers Discuss?

When contributing code to a software system, developers are often confronted with the hard task of understanding and adhering to the system's design. This task is often made more difficult by the lack of explicit design information. Often, recorded design information occurs only embedded in discussions between developers. If this design information could be identified automatically and put into a form useful to developers, many development tasks could be eased, such as directing questions that arise during code review, tracking design changes that might affect desired system qualities, and helping developers understand why the code is as it is. In this paper, we take an initial step towards this goal, considering how design information appears in pull request discussions and manually categorizing 275 paragraphs from those discussions that contain design information to learn about what kinds of design topics are discussed.
ANALYSIS AND IMPROVED DESIGN OF DIRECT-DRIVE CORELESS AFPM IN-WHEEL MACHINE FOR HEV APPLICATION

This paper illustrates the design of in-wheel direct-drive axial flux permanent magnet (AFPM) machine for hybrid electric vehicle (HEV) in order to obtain a wide speed range operation with high operation efficiency and low cogging torque. Using a coreless type of stators can help to improve the total machine efficiency as a result of power loss reduction. In order to achieve the direct drive without any mechanical transmission for HEVs, the wheel motor has been designed as a low-speed high-torque motor. Direct drive, in-wheel motors are ideal for vehicles, because of their high efficiency, compressed packaging, easy handling, and safety operation. The performance analysis of this axial flux permanent magnet in-wheel motor is done using finite-element method and the obtained results verify the validation of this proposed design method. The experimental results obtained from sample practical prototype, confirm the analytical method.
Enhanced Bone Metastases in Skeletally Immature Mice

Bone constitutes the most common site of breast cancer metastases either at time of presentation or recurrent disease years after seemingly successful therapy. Bone metastases cause substantial morbidity, including life-threatening spinal cord compression and hypercalcemia. Given the high prevalence of patients with breast cancer, health-care costs of bone metastases (>$20,000 per episode) impose a tremendous economic burden on society. To investigate mechanisms of bone metastasis, we developed femoral artery injection of cancer cells as a physiologically relevant model of bone metastasis. Comparing young (∼6 weeks), skeletally immature mice to old (∼6 months) female mice with closed physes (growth plates), we showed significantly greater progression of osteolytic metastases in young animals. Bone destruction increased in the old mice following ovariectomy, emphasizing the pathologic consequences of greater bone turnover and net loss. Despite uniform initial distribution of breast cancer cells throughout the hind limb after femoral artery injection, we observed preferential formation of osteolytic bone metastases in the proximal tibia. Tropism for the proximal tibia arises in part because of TGF-β, a cytokine abundant in both physes of skeletally immature mice and matrix of bone in mice of all ages. We also showed that age-dependent effects on osteolytic bone metastases did not occur in male mice with disseminated breast cancer cells in bone. These studies establish a model system to specifically focus on pathophysiology and treatment of bone metastases and underscore the need to match biologic variables in the model to relevant subsets of patients with breast cancer.
Evaluation of the Masticatory Efficiency at the Patients with New Complete Dentures

BACKGROUND: There are a lot of factors influencing the efficiency of mastication; therefore there are also a lot of methods for testing this efficiency. OBJECTIVE: The study aimed to test the efficiency of mastication and evaluate it in the function of time, based on previous experience with the complete dentures. METHODS: A total of 88 patients (42 female, 46 male, mean age 52.2, SD = 5.76), complete dentures wearers, participated in this study. Masticatory functions were investigated by using the method of electromyography (EMG), analyzing electromyomasticatiogram. For testing the masticator efficiency, the further parameters of the masticatiogram were used: duration of the Standard Masticatory Task (SMT) (t), number of the masticatory cycles within the masticator arch (F) and maximal amplitude within the masticatory arch (F). All data were statistically analysed by using standard software package BMDP (bio-medical Statistical package). Parametric data have been tested using One Way Repeated Measurement of ANOVA test. RESULTS: The changes of the relation A/t are evident in different time intervals in both measured sides: F-DS-time of the measurement = 34.86, P = 0.0000; F-NDS- time of the measurement = 26.1, P = 0.0000. There are also differences of the masticatory index A/t between sexes in both, dominant and non-dominant side: F-DS-gender = 237.05, P = 0.0000; F-NDS-gender = 12.90, P = 0.004. Masticatory index (A/F) varies in time, from first to the sixth measurement in both sides: F-DS-time of the measurement = 32.36, P = 0.0000; F-NDS-time of the measurement = 30.53, P = 0.0000. The interaction of the time and gender was also important: F-DS-interaction = 6.95, P = 0.0000; F-NDS-interaction = 14.9, P = 0.0000. CONCLUSION: Masticator indexes are A/F, and A/t are a very important indicator of the masticatory efficiency and the level of the functional adaptation on complete dentures. Both masticator indexes show the same dynamics (reaching the stationary condition after the 15th week after getting new dentures). After the observing period, all examinee express the same degree of masticator efficiency known as functional adaptation. Patients with previous experience with complete dentures reach faster the stationary condition, compared with those non-experienced.
Introductory Chapter: Multi-Aspect Bibliographic Analysis of the Synergy of Technical, Biological and Medical Sciences Concerning Materials and Technologies Used for Medical and Dental Implantable Devices

medicine. Natural rubber latex biomaterials in bone regenerative medicine are presented in the thirteenth chapter. A systematic study of ethylene-vinyl acetate (EVA) in the manufacturing of protector devices for the orofacial system was described in the fourteenth chapter. The next few chapters outline other issues regarding regenerative medicine and tissue engineering. The fifteenth chapter includes tailoring bioengineered scaffolds for regenerative medicine. Biomaterials and stem cells as promising tools in tissue engineering and biomedical applications are the content of the sixteenth chapter. Identification of Fe 3 O 4 nanoparticles biomedical purpose by magnetometric methods is the title of the seventeenth chapter. The eighteenth chapter applies to biomaterials for tissue engineering applications in diabetes mellitus. topics, manufacturing and engineering and advanced biomaterials in regenerative medicine and dentistry. in economic manufacturing of biomaterials and implantable devices; the fate of awareness execution results book.
Anemia among School-Age Children: Magnitude, Severity and Associated Factors in Pawe Town, Benishangul-Gumuz Region, Northwest Ethiopia

Background Anemia is a global public health problem associated with increased mortality and morbidity. The cause of anemia in school-age children is multifactorial and has been associated with delayed psychomotor development, poor cognitive performance, impaired immunity and decrease working capacity. The aim of this study was to determine the magnitude, severity and determinant factors of anemia among school-age children (5–15 years) in Pawe Town, Northwest Ethiopia. Methods A community based cross-sectional study was conducted from March 20 to June 19, 2015 in Pawe Town. A total of 422 school-age children were included in this study. Sociodemographic and related data were collected using structured questionnaire. Anthropometric data were collected from each study participant. Hemoglobin concentration was measured using HemoCue® Hb 201+ System (HemoCue, Angelholm, Sweden). Blood film for malaria diagnoses and stool examination for intestinal parasites were also performed. Data were analyzed using SPSS version 20.0. Results The overall prevalence of anemia among school-age children was 33.9%. Mothers' illiteracy (AOR=7.5, 95% CI: 2.6–16.3), being from a family with low income (AOR=4.8, 95% CI: 1.3–10.9), being stunted (AOR=7.1, 95% CI: 2.9–11.9), being underweight (AOR=5.3, 95% CI: 2.1–13.3), infection with intestinal parasites (AOR=5.2, 95% CI: 2.1–12.6), and malaria infection (AOR=8.2, 95% CI: 1.8–14.5) were identified as associated factors of anemia. Conclusion In this study, anemia is a moderate public health problem among school-age children. School health strategies and interventions targeting nutritional deficiencies and parasitic infections might be very important.
Decentralised output-feedback LQG control with one-step communication delay

ABSTRACT This paper studies the output-feedback LQG control of a two-player system with one-step communication delay. A novel information pattern is considered and a new controller structure is introduced. The proposed controller consists of two parts: the first part is based on estimated system state; the second part is based on current local measurement output. The form of the optimal controller is established using the method of independence decomposition. A necessary condition is established to construct the optimal controller gains. Two iterative algorithms are used to find the optimal gains numerically. Finally, the effectiveness of the theoretical results is illustrated through a numerical example.
The effect of replacing egg yolk with sesame–peanut defatted meal milk on the physicochemical, colorimetry, and rheological properties of low‐cholesterol mayonnaise

Abstract Egg yolk was replaced with sesame–peanut meal milk in mayonnaise in the levels of 0, 25%, 50%, 75%, and 100%. The pH was significantly decreased by increasing the percentage of replacement in all three kinds of replacement (p < .05). However, over the whole period, no significant difference was observed in the acidity. The mayonnaise samples, except for the replacements of 50%, were desirable in terms of physical and thermal stability. A significant decrease was seen in lightness (L*) and yellowness (b*) of the samples as a result of an increase in the percentage of replacements (p < .05). In the power law model, the flowing index amount (n) of all samples was in the domain between zero and one, which served as evidence for pseudoplastic behavior (dilatant with shear) of mayonnaise samples. The positive results are employing suitably the sesame–peanut meal milk instead of egg yolk, decreasing the cholesterol of mayonnaise and increasing its nutritional value, proposing mayonnaise factories to make use of the meal of the oil extraction factory as emulsifier, which lead to a decrease in overall costs of producing these products.
Improving Requirements Engineering Communication in Multi-Project Contexts

In complex multi-project contexts communication is the key to a successful requirements engineering process. In this article we present the notion of an information model which captures the documents and the responsibilities of the stakeholders during requirements engineering. The responsibilities determine authorship, review, approval and the propagation of change of and within the documents. The information model is an effective and practical means to ensure that stakeholders of dependent projects are mutually aware of their most critical communication needs. As an example we present the information model developed at Nokia STP and show how it was defined in a two-day workshop.