Miracle-dz/UniFAR-FTUs huggingface dataset:
Motivational effects of coronary artery calcium scores on statin adherence and weight loss

AimThe aim of this study was to assess the effect on adherence to statin therapy and assess the effect of beneficial changes in behavior that resulted in weight loss in patients who underwent coronary artery calcium (CAC) scoring with cardiac computed tomography. BackgroundDespite convincing data demonstrating the benefits of HmGCoA inhibitors for both primary and secondary prevention of coronary heart disease, they remain underused. Also, despite convincing data demonstrating the benefits of weight loss for both primary and secondary prevention of coronary heart disease, it remains difficult to motivate behavioral changes resulting in weight loss. In this study, we assess whether higher CAC scores are associated with increased compliance with statin medication and whether higher CAC scores are associated with beneficial lifestyle behaviors resulting in weight loss. MethodsWe retrospectively analyzed patients that had undergone baseline CAC testing and returned for a follow-up scan. All patients had weight documented and were administered a questionnaire regarding compliance to medications. The primary endpoint was measurable weight loss between visit one and visit two and the self-reported compliance to statin use. ResultsThe study population with data regarding statin compliance consisted of 2608 individuals (72% men, mean age 58±8 years) who were followed for a mean of 4.1±3.2 years after an initial CAC scan. Overall, statin compliance was lowest (27.4%) among those with CAC=0, and gradually increased with higher CAC scores (1–99, 39.2%; 100–399, 53.6%; ≥400, 58.8%; P<0.001 for trend). In the group analyzed for weight loss the study population consisted of 1078 individuals (68% men, mean age 60±8 years) who were followed for a mean of 4.1±3.2 years after an initial CAC scan. ConclusionOverall, behavioral modification resulting in weight loss was lowest (19.8%) among those with CAC=0, and gradually increased with higher CAC scores (1–99, 23.4%; 100–399, 30.8%; ≥400, 33.6%; P<0.001 for trend). In addition to being a robust risk stratification tool, a higher rate of adherences with statin therapy was observed in patients with higher CAC scores.
The Pseudomonas cepacia 249 chromosomal penicillinase is a member of the AmpC family of chromosomal beta-lactamases

Pseudomonas cepacia 249 produces an inducible beta-lactamase with penicillinase activity. The nucleotide sequence of the penA gene, which encodes this beta-lactamase, was determined and found to include regions with a significant homology to the ampC-encoded beta-lactamases of members of the family Enterobacteriaceae and Pseudomonas aeruginosa. The predicted amino acid sequence of the PenA beta-lactamase contained 17 amino acids immediately preceding the putative active-site serine which were highly conserved among the enzymes of the AmpC family. Although the penA-coding sequence had a total GC content of 60%, the predicted codon usage was more characteristic of Escherichia coli ampC-encoded beta-lactamase, with 53% of the codons having G or C in the third position, in contrast to the values for the P. aeruginosa ampC (88.5%) or Pseudomonas cepacia (88 to 92%) metabolic genes. The inducible expression of penA can be regulated by the E. coli gene product AmpD. A putative P. cepacia AmpR homolog was associated with the positive regulation of both Enterobacter cloacae ampC and P. cepacia penA expression, as confirmed by gel retardation studies. The E. cloacae AmpR did not regulate penA expression. Thus, by homology studies, codon usage, and genetic analysis, the P. cepacia penA beta-lactamase appears to have been acquired from members of the family Enterobacteriaceae and belongs to the class C group of beta-lactamases.
Titanium (IV) and Nickel (II) Catalysts Based on Anilinotropone Ligands

Historically, the development of highly active olefin polymerization catalysts has been a trigger for creating new polymers which impact on our daily lives in countless beneficial ways [1-5]. A recent instance is the development of group 4 metallocene catalysts that exhibit very high ethylene polymerization activities [2,3]. Based on the highly active group 4 metallocene catalysts, high performance linear low-density polyethylene (LLDPE), isotactic poly-(propylene) (iPP) and syndiotactic polystyrene (sPS) etc., have been developed [6]. Therefore, much effort has been directed towards the development of highly active catalysts, following the group 4 metallocene catalysts. In consequence, quite a few highly active catalysts based on both early and late transition metal complexes have been developed [7-14]. There are, however, only a few examples of titanium complexes displaying high ethylene polymerization activities [15-19], though titanium metal is the major player in highly active heterogeneous Ziegler-Natta catalysts. Accordingly, further researches have been conducted on titanium catalysts with the intention of developing the highly active titanium catalysts and applying them to the polymerization of ethylene.
Some practical experience with the use of test suites for the evaluation of SYSTRAN

The purpose of this paper is twofold. On the one hand, we try to give an overview of some results of practical work on the evaluation of the linguistic performance of SYSTRAN’s French → German translation, concentrating on our use of test suites for the purpose of the partial evaluation of this system. Secondly, we try to discuss from a more general point of view the usefulness of test suites for this exercise and for different types of evaluation activities in general. Much time and effort has to be spent on the construction of test suites, and therefore the question has to be addressed under which conditions and in which situations test suites can be most efficiently used as a linguistic evaluation tool, and where other, perhaps less complex, tools may lead to useful results as well. This short paper starts with a general overview of major types of evaluation situations, concentrating on those types which mainly aim at the description of the linguistic part of a machine translation system. We then describe our own work on SYSTRAN and discuss some of our experience with a test suite for verbal subcategorization and for certain other grammatical phenomena, such as tense, embedded structures, etc.
How protein chemists learned about the hydrophobic factor

It is generally accepted today that the hydrophobic force is the dominant energetic factor that leads to the folding of polypeptide chains into compact globular entities. This principle was first explicitly introduced to protein chemists in 1938 by Irving Langmuir, past master in the application of hydrophobicity to other problems, and was enthusiastically endorsed by J.D. Bernal. But both proposal and endorsement came in the course of a debate about a quite different structural principle, the so‐called “cyclol hypothesis” proposed by D. Wrinch, which soon proved to be theoretically and experimentally unsupportable. Being a more tangible idea, directly expressed in structural terms, the cyclol hypothesis received more attention than the hydrophobic principle and the latter never actually entered the mainstream of protein science until 1959, when it was thrust into the limelight in a lucid review by W. Kauzmann. A theoretical paper by H.S. Frank and M. Evans, not itself related to protein folding, probably played a major role in the acceptance of the hydrophobicity concept by protein chemists because it provided a crude but tangible picture of the origin of hydrophobicity per se in terms of water structure.
Calidad y Aceptabilidad de Chorizos Formulados con Plasma Sanguíneo Bovino y Pasta de Ajonjolí

Resumen Se evaluo la calidad y aceptabilidad de productos carnicos tipo chorizo formulados con plasma sanguineo bovino y pasta de ajonjoli. Para esto el contenido proximal y los analisis microbianos se determinaron siguiendo las Normas Tecnicas Colombianas 1663:20 09, 1662:2008, 1556:2008 y las normas INVIMA: 1998, respectivamente . El rendimiento se determino mediante el calculo de las perdidas por coccion, establecida por la diferencia de peso de las muestras antes y despues de la coccion. Para la evaluacion de la aceptabilidad se empleo un panel de degustacion no entrenado conformado por cincuenta jueces, se utilizo una escala hedonica de cinco puntos. Se observo que es posible reemplazar porcentajes de agua por plasma sanguineo bovino y tocino por pasta de ajonjoli en la formulacion de chorizos. Estos mostraron mejorar el rendimiento, aumentar el contenido proteico y reducir el contenido de grasa, sin que ello tenga un efecto negativo en la aceptabilidad.
Behavior of Coliphage Lambda in Shigella flexneri 2a

The insensitivity of wild-type Shigella flexneri 2a to coliphage λ is a consequence of its native genetic defect in the malA gene cluster. The “smooth” S. flexneri 2a lipopolysaccharide layer affects the efficient adsorption of λ. Derivatives, capable of serving as functional hosts for λ, were obtained by repairing the malA lesion, enabling the expression of the malB-λrcp region of S. flexneri. Introduction of a mutation into S. flexneri causing a “rough” lipopolysaccharide character resulted in more efficient adsorption of λ. Such S. flexneri hosts can be stably lysogenized and upon induction yield gal+-transducing lysates. Lambda propagated on a malA+ rough S. flexneri host was restricted by Escherichia coli K-12 and E. coli B, but not by E. coli C. This S. flexneri host did not restrict λ grown on these E. coli strains.
Double-blind, placebo-controlled cross-over study of intravenous S-adenosyl-L-methionine in patients with fibromyalgia.

The objective of this study was to test the efficacy of intravenously administered S-adenosyl-L-methionine (SAMe) in patients with fibromyalgia (FM). Thirty-four out-patients with fibromyalgia symptoms received SAMe 600 mg i.v. or placebo daily for 10 days in a cross-over trial. There was no significant difference in improvement in the primary outcome: tender point change between the two treatment groups. There was a tendency towards statistical significance in favour of SAMe on subjective perception of pain at rest (p = 0.08), pain on movement (p = 0.11), and overall well-being (p = 0.17) and slight improvement only on fatigue, quality of sleep, morning stiffness, and on the Fibromyalgia Impact Questionnaire for pain. No effect could be observed on isokinetic muscle strength, Zerrsen self-assessment questionnaire, and the face scale. No effect of SAMe in patients with FM was found in this short term study.
Next to Nothing: Jean Paulhan’s Gamble

Abstract Articulating together Jean Paulhan’s texts on language, painting and the experience of the Resistance during the Nazi Occupation of France, this article distinguishes between the nothingness or silence that is one face of a totalising opposition – between signs and things – and the ‘small nothings’ that recur throughout Paulhan’s texts. It argues that these ‘nothings,’ odd snippets and scraps of a culture that are overlooked or dismissed rather than reduced to nothing by the priorities of power, offer the possibility of restoring a sense of community when a polity ceases to speak a common language, as arguably occurred in France during the Occupation. Thus it dismisses the claim that Paulhan’s work was essentially apolitical, and challenges the deconstructive approach that concludes on its aporetic nature. In contrast, it concludes that Paulhan offers a vital reflection on the power of words to ground a common purpose.
Character-Position Arithmetic for Analogy Questions between Word Forms

We show how to answer analogy questions A : B :: C : D of unknown D between word forms, by essentially relying on the basic arithmetic equality D [ i B − i A + i C ] = B [ i B ] − A [ i A ] + C [ i C ] on characters and positions at the same time. We decompose the problem into two steps: speciﬁcation and decoding. We examine several techniques to implement each of these two steps. We perform experiments on a set of positive and negative examples and assess the accuracy of combinations of techniques. We then evaluate the performance of the best combination of techniques on a large set of more than 40 million analogy questions from the training data of a shared task in morphology. We obtain the correct answer in 94 % of the cases.
Rural nurses’ perceptions of a volunteer program in an acute setting: Volunteers delivering person-centred care for patients with dementia and delirium

Community volunteers were recruited and trained to deliver person-centred care to patients with dementia or delirium in an acute hospital setting, in a small rural Australian hospital. The volunteer program was grounded in action research methodology, and modelled on a previous research project. As a form of evaluation, interviews were conducted with nursing staff eight weeks after implementation of the volunteer program to explore their opinions. Data were analysed through a collaborative process and findings revealed strong benefits from the perspectives of the nursing staff. These benefits included overall improved patient care and improved time management for nursing tasks.
Ontogeny of serine hydroxymethyltransferase isoenzymes in fetal sheep liver, kidney, and placenta.

Serine is an amino acid that is not transported from the placenta to the ovine fetus. Thus, fetal plasma serine levels may be controlled by flux through their relevant biosynthetic pathways. This study was designed to determine, in fetal sheep tissues, the ontogeny of the three key enzymes in the biosynthetic pathway for serine, the cytosolic (c) and mitochondrial (m) isoforms of serine hydroxymethyltransferase (SHMT), phosphoglycerate dehydrogenase (PGD), and phosphoserine aminotransferase (PSAT). PGD and PSAT activity did not vary during gestation in either liver (PSAT, 9.4 +/- 1.3 nmol/min/mg cytosolic protein; and PGD, 76 +/- 10 mU/mg protein) or placenta (PGD, 8.0 +/- 3.6 mU/mg protein). In the liver, cSHMT activity was low early in gestation (0.6 +/- 0.5 nmol/min/mg protein at 45 days), rose in the last one-third of gestation, and peaked in the newborn period (25 +/- 3 nmol/min/mg protein at 1 week of age). Hepatic cSHMT RNA levels parallel the activity pattern. Mitochondrial SHMT was stable throughout gestation and with low constant mSHMT RNA levels. In contrast, the kidney and placenta had high mSHMT and steady low cSHMT activity throughout gestation. These data support the possible role of SHMT in the fetal control of plasma serine levels. While cSHMT may contribute to fetal hepatic serine production, its activity pattern does not support a primary role in the control of fetal hepatic serine biosynthesis. In the placenta, mSHMT may be important for glycine production from serine.
Pathology of Traveling-Salesman Subtour-Elimination Algorithms

The traveling-salesman problem has been the target of a substantial number of computational algorithms over the last two decades. Reported computational experience with these algorithms varies widely; authors, however, have generally failed to explain this variation adequately, or to offer predictive theories for their approaches. This paper a develops an underlying theory for the problem, b predicts pathological performance of some existing techniques, and c presents two algorithms, based upon the theory, with predictable polynomial growth in expected computation time and resistence to pathological problems.
Genetics of Right Ventricular Cardiomyopathy

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may result in arrhythmia, heart failure, and sudden death. The hallmark pathological findings are progressive myocyte loss and fibrofatty replacement, with a predilection for the right ventricle. However, variants of ARVC that preferentially affect the left ventricle are increasingly recognized. ARVC is distinguished from dilated cardiomyopathy by a propensity toward ventricular arrhythmia and sudden death in the absence of significant ventricular dysfunction.
Information technology for time series forecasting with considering fuzzy expert evaluations

The task of designing information technology for time series forecasting, that bases on fuzzy expert evaluations, were considered. A forecasting model, part of which is an expert's unit, were proposed. To determine expert evaluation of the forecast value, the task of forecasting was seen as the problem of numerical evaluation of object. The analysis of features for designing information-analytical system of time series forecasting were done.
Molecules and Croquet Balls

structures and training the mind’s eye by manipulating physical objects. Both had their own syntax built into their mechanical joints, and both carried an implicit message that went beyond epistemology: the bourgeois ideal of taking possession of space by constructing it. Of course we do not need to assume that Hofmann and his fellow chemists took Kindergarten toys as their source of inspiration. Yet at the time it would have been almost impossible not to be familiar with their existence and meaning. The sheer explosion of assembly kits during the second half of the nineteenth century testifies to the spread of construction thinking through Europe. The Frobel gifts and the molecular models were part of this same movement.
Pragmatic computation in language acquisition: Evidence from disjunction and conjunction in negative context

Title of dissertation: PRAGMATIC COMPUTATION IN LANGUAGE ACQUISITION: EVIDENCE FROM DISJUNCTION AND CONJUNCTION IN NEGATIVE CONTEXT Chunyuan Jing, Doctor of Philosophy, 2008 Directed by: Professor Jeffery Lidz Department of Linguistics This dissertation discusses contributions from pragmatic factors to children’s behavior in interpreting scopally ambiguous forms. In particular, we look at children’s interpretation of negated sentences involving disjunction in the object (Neg.Disjunction). Languages like English and Chinese allow scope interaction between negation and disjunction of this kind of strings and thus two corresponding interpretations: the narrow scope disjunction interpretation (the NSD, meaning “neither”) and the wide scope disjunction interpretation (the WSD, meaning “not this or not that”); but languages like Japanese only allow the WSD. Previous studies found out that children of different languages accessed the NSD instead of the WSD given “not this or not that” scenarios (e.g., Crain, Gualmini & Meroni 2000; Goro & Akiba 2004a; Jing, Crain & Hsu 2005) and concluded that preschool children systematically lack the WSD in their grammar. However, given the fact that the WSD is pragmatically more complex than the NSD in general and the well documented observations that children’s immature capacity in pragmatic computation sometimes masks their linguistic competence (e.g., Gualmini 2004; Musolino & Lidz 2006), the findings in previous studies could reveal children’s strong preference toward the NSD rather than their lack of the WSD. Four main experiments are reported in this dissertation, which aim to test the hypothesis that children’s grammar can generate the WSD and that children can access this interpretation when the relevant pragmatic computation is facilitated. With various kinds of experimental manipulations to facilitate children’s pragmatic computation, we observed that children accessed the normally dispreferred WSD more often, when the “not this or not that” meaning was made more directly relevant in the context, when explicit disambiguating information was present in the discourse, after they were trained to be more sensitive to the “not this or not that” aspect of the context, and after they immediately experienced the use of certain alternative form (Neg.Conjunction) to express the “neither” meaning (corresponding to the NSD of Neg.Disjunction). The findings in these experiments reveal children’s hidden grammatical knowledge of the WSD and highlight the role of pragmatic computation in the acquisition of meaning. PRAGMATIC COMPUTATION IN LANGUAGE ACQUISITION: EVIDENCE FROM DISJUNCTION AND CONJUNCTION IN NEGATIVE CONTEXT
Factors affecting sound coloration perceived due to room reverberation

The aim of this article is to characterize the coloration due to synthesized room reverberation. Based on the calculation of the eigen-functions, the room reverberation is generated and a set of reverberation features is listed. The sound coloration perceived due to the room reverberation is measured, and the factors affecting the coloration perceived are investigated.
Integrating Motion and Segmentation for Road Scene Labeling

Structure from motion (SfM) and appearance-based segmentation have played an important role in the interpretation of road scenes. The integration of these approaches can lead to good performance during interpretation since the relation between 3D spatial structure and 2D semantic segmentation can be taken into account. This paper presents a new integration framework using an SfM module and a bag of textons method for road scene labeling. By using a multiband image, which consists of a near-infrared and a visible color image, we can generate better discriminative textons than those generated by using only a color image. Our SfM module can accurately estimate the ego motion of the vehicle and reconstruct a 3D structure of the road scene. The bag of textons is computed over local rectangular regions: its size depends on the distance of the textons. Therefore, the 3D bag of textons method can help to effectively recognize the objects of a road scene because it considers the object's 3D structure. For solving the labeling problem, we employ a pairwise conditional random field (CRF) model. The unary potential of the CRF model is affected by SfM results, and the pairwise potential is optimized by the multiband image intensity. Experimental results show that the proposed method can effectively classify the objects in a 2D road scene with 3D structures. The proposed system can revolutionize 3D scene understanding systems used for vehicle environment perception.
Leakage Current Calculation for PV Inverter System Based on a Parasitic Capacitor Model

The occurrence of leakage current that can occur in photovoltaic (PV) system depends strongly on the value of parasitic capacitance between PV panel and the ground. However, traditional method to acquire that value is by experience estimation. This paper presents a novel 2-D parasitic edge capacitance model and a straightforward approach to accurately calculate the involved panel parasitic capacitance. The parasitic capacitances are divided into cell-to-frame capacitance Ccf , cell-to-rack capacitance Ccr, and cell-to-ground capacitance Ccg. Based upon that, a pi-shape circuit model is derived to predict the leakage current in the PV array. Theoretical calculation, MATLAB simulations, and experimental measurements finally verify the accuracy of the proposed methods. The approaches are very useful for the evaluation of leakage current in the PV system. It is demonstrated that the proposed approach combines the ease of applications and satisfying accurateness.