Miracle-dz/UniFAR-FTUs huggingface dataset:
Digestibility of hydrogenated tallow, saturated fatty acids and soybean oil-supplemented diets by sheep.

A TOTAL of 28 crossbred wethers were used in two experiments to determine the digestibilty of hydrogenated tallow-, saturated fatty acidsand soybean oil-supplemented diets. Digestibility values for individual fats were determined by subtracting from total dietary lipid and fecal output the dietary and fecal lipids measured with basal diets. In the first experiment addition of 3% flaked, hydrogenated tallow to a basal diet resulted in lower digestibility (34%) for the tallow compared with soybean oil (98%). In the second experiment, hydrogenated tallow was added to a basal diet at approximately the 4.8% level either in dry flaked form or melted and mixed (blended) into the concentrate portion of the basal diet. A further treatment comparison involved addition of saturated free fatty acids at approximately the 4.8% level to the basal diet. Tenday digestion trials were conducted starting at 10 and again at 35 days of this experiment to measure adaptation of sheep to fat-supplemented diets. Melting and mixing the tallow into the diet resulted in significant (P< .01) improvement in digestibility over flaked tallow (40% vs. 30%). Saturated fatty acids were significantly (P<.01) better digested (73%) than either form of tallow. Blood plasma lipid fatty acid levels of sheep reflected these differences in digestibility after 33 days on feed. It is suggested that the hydrogenation process results in tallow with physical form which resists dispersion and hydrolysis in the rumen and solubilization in the small intestine. Additions of soybean oil, saturated fatty acids and hydrogenated tallow tended to lower digestibilities of crude fiber and acid detergent fiber. The decreases were significant
Confusion and inconsistency in diagnosis of Asperger syndrome: a review of studies from 1981 to 2010

This paper presents a review of past and current research on the diagnosis of Asperger syndrome (AS) in children. It is suggested that the widely used criteria for diagnosing AS in the Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV are insufficient and invalid for a reliable diagnosis of AS. In addition, when these diagnostic criteria are applied, there is the potential bias of receiving a diagnosis towards the high-functioning end of the autism spectrum. Through a critical review of 69 research studies carried out between 1981 and 2010, this paper shows that six possible criteria for diagnosing AS (specifically, the age at which signs and symptoms related to autism become apparent, language and social communication abilities, intellectual abilities, motor or movement skills, repetitive patterns of behaviour and the nature of social interaction) overlap with the criteria for diagnosing autism. However, there is a possibility that some finer differences exist in the nature of social interaction, motor skills and speech patterns between groups with a diagnosis of AS and autism. These findings are proposed to be of relevance for designing intervention studies aimed at the treatment of specific symptoms in people with an autism spectrum disorder.
Measuring HTTPS Adoption on the Web

HTTPS ensures that the Web has a base level of privacy and integrity. Security engineers, researchers, and browser vendors have long worked to spread HTTPS to as much of the Web as possible via outreach efforts, developer tools, and browser changes. How much progress have we made toward this goal of widespread HTTPS adoption? We gather metrics to benchmark the status and progress of HTTPS adoption on the Web in 2017. To evaluate HTTPS adoption from a user perspective, we collect large-scale, aggregate user metrics from two major browsers (Google Chrome and Mozilla Firefox). To measure HTTPS adoption from a Web developer perspective, we survey server support for HTTPS among top and long-tail websites. We draw on these metrics to gain insight into the current state of the HTTPS ecosystem.
Amygdala Plasticity and Pain

The amygdala is a limbic brain region that plays a key role in emotional processing, neuropsychiatric disorders, and the emotional-affective dimension of pain. Preclinical and clinical studies have identified amygdala hyperactivity as well as impairment of cortical control mechanisms in pain states. Hyperactivity of basolateral amygdala (BLA) neurons generates enhanced feedforward inhibition and deactivation of the medial prefrontal cortex (mPFC), resulting in pain-related cognitive deficits. The mPFC sends excitatory projections to GABAergic neurons in the intercalated cell mass (ITC) in the amygdala, which project to the laterocapsular division of the central nucleus of the amygdala (CeLC; output nucleus) and serve gating functions for amygdala output. Impairment of these cortical control mechanisms allows the development of amygdala pain plasticity. Mechanisms of abnormal amygdala activity in pain with particular focus on loss of cortical control mechanisms as well as new strategies to correct pain-related amygdala dysfunction will be discussed in the present review.
Identification of a Potent Inhibitor of Human Dual‐Specific Phosphatase, VHR, from Computer‐Aided and NMR‐Based Screening to Cellular Effects

Human vaccinia H1‐related phosphatase (VHR) is a dual‐specific phosphatase (DSPs) that plays an important role in the mitogen‐activated protein (MAP) kinase cascade regulation. It is also a potential drug target for diseases that are related to immune response. By combining a virtual and NMR‐based ligand‐screening strategy, we successfully identified four VHR inhibitors, of which GATPT ((glucosamine‐aminoethoxy)triphenyltin) can bind to VHR with a Ki value of 2.54 μM. The putative binding mode of GATPT was constructed by a molecular docking simulation to provide structural insights into the ligand‐binding mechanism. Furthermore, we found that this compound can significantly inhibit the dephosphorylation of the extracellular regulated kinases (ERKs), and c‐Jun N‐terminal kinases (JNKs) and block the G1–S phase transition in the cell cycle. Therefore, GATPT is a promising lead structure for designing more effective inhibitors of VHR.
Faster and Energy-Efficient Signed Multipliers

We demonstrate faster and energy-efficient column compression multiplication with very small area overheads by using a combination of two techniques: partition of the partial products into two parts for independent parallel column compression and acceleration of the final addition using new hybrid adder structures proposed here. Based on the proposed techniques, 8-b, 16-b, 32- b, and 64-b Wallace (W), Dadda (D), and HPM (H) reduction tree based Baugh-Wooley multipliers are developed and compared with the regular W, D, Hbased Baugh-Wooley multipliers. The performances of the proposed multipliers are analyzed by evaluating the delay, area, and power, with 65 nm process technologies on interconnect and layout using industry standard design and layout tools. The result analysis shows that the 64-bit proposed multipliers are as much as 29%, 27%, and 21% faster than the regular W, D, H based Baugh-Wooley multipliers, respectively, with a maximum of only 2.4% power overhead. Also, the power-delay products (energy consumption) of the proposed 16-b, 32-b, and 64-b multipliers are significantly lower than those of the regular Baugh-Wooley multiplier. Applicability of the proposed techniques to the Booth-Encoded multipliers is also discussed.
Emerging Trends in Changing HR Technology and its Landscape

Technology is changing everything and impacting most every part of every business. Innovative human resource practices have reengineered the old process. Today human resource managers have innovated their way of hiring and recruiting employees. Innovative HR practices have overcome various human capital challenges viz. geographical limitations, mobilization etc. Human resources technology helps in all processes from recruit to retire functions and has drastically changed the way employees and managers get access to the human resource data. The past decade taught business firms everywhere a humbling lesson. Domestic companies learned that they can no longer ignore global markets and competitors. Successful firms in mature industries learned that they cannot overlook emerging markets, technologies, and management approaches. Companies of every sort learned that they cannot remain inwardly focused, ignoring the needs of customers and their environment. The key components to an effective human resource team consist of finding solutions that address their biggest challenges with respect to personnel and technology. Using the best in HR Technology to stay ahead of the curve just makes sense. This paper explores the available technology and its usefulness in executing the managerial functions and challenges faced by them. Indeed technology rules the world and HR people enjoy the fruits of benefits and one can not wish away the organizational which can accommodate with caution and human touch. No one can deny the fact that no doubt that technology has made it easier and faster to gather, collate, and deliver information and communicate with employees. More importantly, it has the potential to reduce the administrative burden on the HR department so it is better able to focus on more meaningful HR activities, such as providing managers with the expertise they need to make more effective HR related decisions. Mobile technology adds values to the HR and presents numerous web based applications to HR people.
Effects of Openness, Problem Solving, and Blaming on Learning: An Experiment in China

Researchers have considered interdependence and interaction among individuals and groups as critical for promoting learning in organizations. In an experiment with 80 participants in China, the present authors found that (a) open discussion compared with avoiding discussion and (b) problem solving compared with blaming stimulated the exploration, integration, and adoption of alternative ideas in addition to strengthening interpersonal relationships. The results also indicated the possibility that openness and problem solving have these effects by developing a perceived cooperative interdependence that encourages people to believe that incorporating alternative ideas can help them succeed. Avoidance and blaming, on the other hand, seemed to result in a competitive struggle to see who could impose their ideas on the other, leaving people committed to their original thinking.
FACTORS INFLUENCING ACQUISITION OF STRESSED ASSETS AND ASSET SECURITIZATION INTO THE FINANCIAL MARKET IN KENYA

Securitization of future receivables has become increasingly popular in Kenya with many Kenyan organizations using this route for raising and investing funds. Banks, financial institutions, insurance firms, stock brokers, housing finance companies, power generators and distributors have already adopted asset securitization. The purpose of this study was to investigate the factors influencing the acceptance of the acquisition of stressed assets (Bad Debts) and asset securitization for the purposes of liquidity mobbing to attain financial stability in the financial market in Kenya. The study was guided by four research objectives: determining the organizational factors that influences the Acquisition of stressed Assets and Asset securitization in the financial market in Kenya; examining the business environment factors that influence acquisition of stressed assets and Asset Securitization in the financial market in Kenya; establishing the effects of Government policies, control, and regulations on acquisition of stressed assets and asset securitization in the financial market in Kenya and to investigate the adequacy of IAS 39 as financial instrument on recognition and measurement. The study adopted a descriptive research design. The population of the study comprised of the finance officers from
An eHealth approach to treating vasomotor symptoms.

benefit; in MENOS2, women in the self-guided CBT arm who H ot flashes and night sweats (vasomotor symptoms [VMS]), the cardinal symptoms of the menopause, affect more than 80% of women during the menopausal transition. A 2016 consensus statement by The North American Menopause Society (NAMS) and other menopause societies concluded that hormone therapy (HT) is the most effective treatment for VMS. However, the use of HT declined by 70% after the Women’s Health Initiative (WHI) identified adverse effects, including cardiovascular disease, cancer, stroke, and thrombotic events, particularly after age 60. These adverse effects underscored the need for safe and effective nonhormonal therapies for VMS. The 2015 NAMS position statement, Nonhormonal Management of Menopause-associated Vasomotor Symptoms, recommended cognitive behavioral therapy (CBT) as an effective treatment for VMS. This recommendation was based on compelling evidence from two randomized clinical trials. The first of these trials, MENOS1, included 96 breast cancer survivors who were randomized to receive usual care or usual care plus one weekly 90-minute session of group CBT for 6 weeks. Group CBT involved psycho-education, paced breathing, relaxation, and cognitive and behavioral strategies to manage VMS. Psychoeducational and discussion topics included the physiology of VMS, the role of stress in triggering VMS, catastrophic thinking and negative beliefs about VMS, and sleep hygiene. CBT significantly reduced VMS problem ratings at 9 weeks after randomization compared with usual care, and improvements were maintained at 26 weeks. The second randomized trial, MENOS2, showed efficacy of self-guided and group CBT compared with usual care in 140 perimenopausal and postmenopausal women without a history of breast cancer. Compared with usual care, both group and self-guided CBT reduced VMS problem ratings, and improvements were maintained at 26 weeks. Thus, both group CBT and self-guided CBT are effective in treating VMS. Although the group CBT manual and the self-guided CBT manual used in the MENOS trials are available, CBT is not widely used in the treatment of VMS. First, many women and healthcare providers are unaware of the evidence supporting CBT for VMS. Second, few providers are trained in CBT tailored for VMS, and transportation, time constraints, health coverage, and stigma limit use of face-to-face CBT. Selfguided CBT overcomes those barriers, but providers and patients are generally not aware that a manual is available. Following through on the manual is key to deriving clinical
Fingerprint Based ATM Security by using ARM7

The purpose of this project is to increase the security that customer use the ATM machine. Once user's bank card is lost and the password is stolen, the criminal will draw all cash in the shortest time, which will bring enormous financial losses to customer, so to rectify this problem we are implementing this project. The chip of LPC2148 is used for the core of microprocessor in ARM7, furthermore, an improved enhancement algorithm of fingerprint image increase the security that customer use the ATM machine.
Minimizing deletion mutagenesis artifact during Taq DNA polymerase PCR by E. coli SSB.

Many artifacts during Taq DNA polymerase PCR have been reported, especially with PCR targets containing stable secondary structure (1, 2, 3, 4). The consequence with PCR targets containing stable secondary structure usually is either very low efficiency in PCR yield, or deletion mutagenesis in the PCR products (1, 2). Pallansch et al. have estimated that AG for such stable secondary structures calculated by the FOLD computer program is <-14 kcal/mol for RNA target (2). This kind of deletion mutagenesis is DNA polymerase dependent (1), and probably determined by polymerase processivity. The Taq DNA polymerase used in PCR has relatively low processivity (6). Highly processive enzymes may be able to overcome this problem. Interestingly, Cariello et al. have successfully used a thermolabile highly processive modified DNA polymerase (SequenaseC) to amplify a segment of 18S rRNA-encoding gene without PCR deletion mutagenesis I described the use E. single-strand binding minimize artifacts during Taq polymerase Cariello here to amplify a 18S rRNA-encoding upper (389 bp) PCR Ag lower
The Body Shop and the role of design in retail branding

Purpose – To demonstrate how a company's retail store design relates to its brand and is influenced by, and contributes to, its corporate values.Design/methodology/approach – The case study briefly summarises the significance of corporate values, branding and design in the retail industry, and subsequently explores The Body Shop's application of these elements to its business. The case study is contextualised by The Body Shop's retail environment forming a particularly important communication channel for the company.Findings – The Body Shop has in many ways been the victim of its own success. Being a unique proposition, and having effectively created its own retail category, it has appeared slow to evolve its brand identity. The strong association between the company and its campaigning founder, increasing competition and changing consumer attitudes, have been significant factors in the company's struggle to re‐align and update its brand.Research limitations/implications – The case study largely draws on .
Band-Pass Non-TEM Mode Traveling-Wave Electro-Optical Polymer Modulator for Millimeter-Wave and Terahertz Application

High-frequency electro-optical modulator is critical for enabling signal processing and distribution in the next generation cloud-computing, tele-medicine, and telecommunications. In this paper, substrate integrated waveguide (SIW) is exploited as an alternative fundamental transmission line structure in support of electrical signal for the design and development of millimeter-wave and terahertz (THz) traveling-wave polymeric electro-optic (EO) modulator. Optical and full-wave electromagnetic analyses are carried out and structure optimization is made on the basis of such analyses in order to obtain millimeter-wave transmission characteristics and optical response. Compared to its conventional TEM-mode transmission lines, this bandpass non-TEM mode SIW-based EO modulator presents numerous advantages, namely compact structure, low transmission loss, low driving power, simple packaging and flat optical response over a wide frequency range.
Personality Differences and Hotel Web Design Study Using Targeted Positive and Negative Association Rule Mining

As people have unique tastes, the way to satisfy a small group of targeted customers or to be generic to meet most people's preference has been a traditional question to many fashion designers and website developers. This study examined the relationship between individuals’ personality differences and their web design preferences. Each individual's personality is represented by a combination of five traits, and 15 website design-related features are considered to test the users’ preference. We introduced a data mining technique called targeted positive and negative association rule mining to analyze a dataset containing the survey results collected from undergraduate students. The results of this study not only suggest the importance of providing specific designs to attract individual customers, but also provide valuable input on the Big Five personality traits in their entirety.
Proteomic analysis of larval integument, trachea and adult scale from the silkworm, Bombyx mori

Multidimensional LC‐tandem MS was used to investigate the protein compositions of three tissues of silkworm, Bombyx mori. A total of 162, 259, and 175 peptides from silkworm larval integument and trachea, and adult scale obtained by database search were matched to 48, 51, and 40 proteins, respectively. Forty‐one cuticular proteins were identified from three tissues and covered all five cuticular protein families of silkworm. In the adult scale, all seven cuticular proteins were identified for the first time in the final pellet after SDS extraction. The majority of cuticular proteins were found in each tissue differentially, suggesting that tissue‐specific cuticular proteins were involved in the building of the specialized tissues. Seventy‐three non‐cuticular proteins were also identified in this analysis mainly including muscular proteins, proteinases, inhibitors, transport proteins, and redox‐related proteins.
Impact of Audit Quality and Financial Performance of Quoted Cement Firms in Nigeria

The financial statement audit is an important tool for reducing information asymmetries and maintaining an efficient market environment. However, if the audit is to improve financial performance, there must be credibility and reliability as regards audited financial information. This research work was designed to examine the impact of audit quality on financial performance of quoted firms in Nigeria. The study is descriptive in nature and the correlational and ex-post facto designs were adopted in carrying out this research. Data were obtained basically from the published annual reports and accounts, and notes to the financial statements of the four firms that represent the sample of the study. The data collected were quantified and presented in tables. Multiple regression analysis using the SPSS Version 15.0 was employed in analyzing the data and testing the stated hypotheses. The results of the findings shows that auditor size and auditor independence have significant impacts on the financial performance of quoted cement firms in Nigeria. However, auditor independence has more influence than auditor size on financial performance. The study recommends that the management of quoted cement firms in Nigeria increase the remuneration of auditors in order to improve their financial performance. The study further recommends that management should employ the services of audit firms whose character and integrity is beyond question.
A small stem-loop structure of the Ebola virus trailer is essential for replication and interacts with heat-shock protein A8

Ebola virus (EBOV) is a single-stranded negative-sense RNA virus belonging to the Filoviridae family. The leader and trailer non-coding regions of the EBOV genome likely regulate its transcription, replication, and progeny genome packaging. We investigated the cis-acting RNA signals involved in RNA–RNA and RNA–protein interactions that regulate replication of eGFP-encoding EBOV minigenomic RNA and identified heat shock cognate protein family A (HSC70) member 8 (HSPA8) as an EBOV trailer-interacting host protein. Mutational analysis of the trailer HSPA8 binding motif revealed that this interaction is essential for EBOV minigenome replication. Selective 2′-hydroxyl acylation analyzed by primer extension analysis of the secondary structure of the EBOV minigenomic RNA indicates formation of a small stem-loop composed of the HSPA8 motif, a 3′ stem-loop (nucleotides 1868–1890) that is similar to a previously identified structure in the replicative intermediate (RI) RNA and a panhandle domain involving a trailer-to-leader interaction. Results of minigenome assays and an EBOV reverse genetic system rescue support a role for both the panhandle domain and HSPA8 motif 1 in virus replication.