Miracle-dz/UniFAR-FTUs huggingface dataset:
A Secure Monitoring Of 46 Habit Drugs Using Abe in Cloud

They will be no longer counter drugs and will be sold only through a doctor's prescription. According to the government notifications chemist should maintain the information such as patient name, prescribed doctor name and amount of 46 habit drugs sold. Such information should be maintained for three years, later the Drug and Control General of India, and zonal authorities will appear for inspection. To make this problem simpler we bring our concept where each and every chemist is provided with service software to update all the necessary information (patient name, prescribed doctor name, antibiotic name, quantity sold, and opening stock, closing stock) to the centralized cloud by using the mobile or computer weekly/daily. As we use cloud for storing drugs details, the data will be secure and it is not going to be tampered. The sub zonal officer can sit in a sub zonal office and can see the information all through the year. They can set the limit on drugs and can check for any deviations, if any the corrective measures can be taken zonal wise, state wise, district wise and even individual chemist details can be tracked by drug control authority without any hassle.
A complication of reduced insulin sensitivity in type 1 diabetes

tion rate [GFR] loss . 3 mL/min/1.73 m 2 per year)dwith three Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations over 6 years. Subjects with diabetes (n =4 49) and without diabetes (n = 565) in the Coronary Artery Calcification in Type 1 Diabetes study had an estimated insulin sensitivity index (ISI) at baseline and 6-year follow-up. RESULTSdThe ISI was lower in subjects with diabetes than in those without diabetes (P , 0.0001). A higher ISI at baseline predicted a lower odds of developing an ACR $30 mg/g (odds ratio0.65[95%CI0.49–0.85],P=0.003)univariatelyandafteradjustingforHbA1c(0.69[0.51– 0.93], P = 0.01). A higher ISI at baseline conferred protection from a rapid decline of GFR as assessed by CKD-EPI cystatin C (0.77 [0.64–0.92], P = 0.004) and remained significant after adjusting for HbA1cand age (0.80 [0.67–0.97],P = 0.02). We found no relation between ISI and rapid GFR decline estimated by CKD-EPI creatinine (P = 0.38) or CKD-EPI combined cystatin C and creatinine (P = 0.50). CONCLUSIONSdOver 6 years, a higher ISI independently predicts a lower odds of developing microalbuminuria and rapid GFR decline as estimated with cystatin C, suggesting a relationship between insulin sensitivity and early phenotypes of DN. Diabetes Care 36:3678–3683, 2013
Correlations of OSA Severity and Carotid Intima-Media Thickness in Patients with Type 2 Diabetes

Aim: To determine whether carotid intima-media thickness (C-IMT) was elevated in diabetic patients with Obstructive Sleep Apnea (OSA), and correlations of OSA severity with IMT and other clinical characteristics. Materials and methods: The study subjects were composed of 36 diabetic patients with OSA (group A), and 34 patients without OSA (group B). In both groups, blood lipids, fasting blood glucose, glycated hemoglobin, Epworth Sleepiness Scale, C-IMT and carotid resistance index (C-RI) were assessed, and results of sleep study were collected to investigate possible correlations with IMT and other clinical characteristics. Results: We found a statistically significant higher IMT value (0.93 ± 0.14 vs 0.83 ± 0.16, P=0.007), C-RI (0.72 ± 0.05 vs 0.68 ± 0.05, P=0.001), and waist circumference (95.00 ± 11.24 vs 88.74 ± 8.34, P=0.010) in diabetic patients with OSA. Carotid IMT was associated with waist circumference, BMI, LDL-C, AHI (r=0.415, P<0.001), ODI (r=0.474, P<0.001), LSaO 2 , and C-RI. AHI was associated with waist circumference, BMI, IMT, ODI, LSaO2, and C-RI (P<0.05). Conclusion: Our study showed that in a group of diabetes, IMT was elevated in those with OSA, and OSA severity positively related to IMT values, indicating that in diabetic patients, OSA severity can be associated with atherosclerosis risk.
XI. Development of a Water-Soluble Contrast Medium with Low Diffusion Rate

Manipulation of a catheter into one of the branches of the hepatic artery enabled contrast medium to be deposited in high concentration in that branch (Chapter VIII). In spite of this no draining hepatic veins could be observed in the angiograms. It was concluded that a substantial proportion of the contrast medium had diffused through the capillary wall out into the interstitial fluid resulting in a low concentration of contrast medium in the draining veins. Using a densitometric method BOLIN (1966) found that a large amount of the contrast medium (diatrizoate) injected into a renal artery diffused from the renal capillaries into the tubular cells. Attempts were made to find a theoretical basis for the development of a contrast medium for arteriography that did not diffuse or diffused slowly through the capillary walls with a consequently higher concentration of the medium in the draining veins. The theory formulated was presented to a pharmaceutical company and led to the synthesis of a macromolecular water-soluble contrast medium. In the classical works of BROMAN and OLSSON (1948-1956) it was shown that the toxic effect of the then available contrast media on the blood-brain barrier was due both to the chemotoxic and the osmotic properties of the contrast media. The osmotic pressure of the contrast media can be reduced by using them as colloids in the form of emulsions, suspensions or macromolecules. A contrast medium that does not pass through the walls of capillaries is desirable. Colloid contrast media have therefore been tried for angiography. Some of the problems encountered in the synthesis of radiopaque emulsions or suspensions for angiography are:
Treatment With Carfilzomib: A Promising Future for Multiple Myeloma

The survival outlook for patients with multiple myeloma (MM) has improved over the past decade; however, even with access to newer therapies, all patients will eventually relapse and progress. Carfilzo - mib is a selective proteasome inhibitor and a promising MM treatment that was approved by the US Food and Drug Administration (FDA) in 2012. This review will highlight the future of carfilzomib by summariz - ing how the agent is being investigated in ongoing clinical trials. While standard carfilzomib (FDA-approved dose and schedule) is effective for MM treatment, clinical trials are investigating alternate dosing schemes of carfilzomib, including higher doses with longer infusion times and altered dosing schedules. Additionally, combination studies are elucidat - ing important treatment options, both for patients who have relapsed and refractory MM and for patients who are newly diagnosed with MM. Drug combinations with carfilzomib have the potential to offer novel treatment options and improved overall survival. Finally, ongoing phase III randomized studies with carfilzomib will establish a broader represen - tation of the many potential capabilities of the drug. The results of these trials will help to further define the role of carfilzomib in MM therapy, which may help to provide patients with improved overall survival and quality of life. J Adv Pract Oncol 2013;4(Suppl 1):33-43
Perfil psicomotor de niños de 5 a 12 años diagnosticados clínicamente de trastorno por déficit de atención/hiperactividad en Colombia

Introduccion. Una de las alteraciones comorbidas del trastorno por deficit de atencion/hiperactividad (TDAH) se manifiesta en la motricidad, hasta el punto de que la calidad del desempeno motor durante los 5-6 primeros anos de vida podria constituir un predictor de la posterior aparicion de sintomas del trastorno. Ademas, la asociacion entre torpeza motora y TDAH supone un peor pronostico del cuadro. Sin embargo, son pocos los trabajos que estudian la evolucion de la motricidad en los ninos afectados. Objetivo. Caracterizar el perfil psicomotor de los ninos entre 5 y 12 anos diagnosticados clinicamente con TDAH en la ciudad de Manizales (Colombia) y compararlo con ninos sanos de su misma edad. Sujetos y metodos. Estudio descriptivo transversal con una muestra de 846 ninos (422 diagnosticados de TDAH y 424 sanos). Resultados. Si bien todos los factores de la motricidad presentaron valores en rangos de normalidad, fueron significativamente peores (p < 0,000) en los ninos diagnosticados en todas las edades. Conclusiones. El perfil psicomotor de los ninos diagnosticados con TDAH fue eupraxico y se clasifica en la misma categoria que los ninos sanos, aunque cuantitativamente resulto inferior.
Factors Affecting Discipline (Major) Choice among Newly Admitted Students of Nursing in Kerman University of Medical Sciences

Introduction: Appraising the factors affecting the choice of nursing major may help to identify and improve incentives for choosing this profession. This study is an endeavor to determine factors affecting the choice of discipline among newly admitted nursing students of Kerman University of Medical Sciences. Methods: In this descriptive cross sectional study, all newly admitted nursing students in Kerman University of Medical Sciences were entered into study through census (n=82). Data gathering tool was a questionnaire made by researcher. Data was analyzed using independent t test, paired t test, and repeated measure ANOVA. Results: According to the students, the most effective reason for choosing nursing was “eager to help people” and the least effective one was “having experience of health care before education”. Personal and professional factors were the foremost reason for choosing this discipline. Comparing the effect of three domains of personal (61.67%), environmental (38%), and professional (62.33%) on choosing the discipline revealed a significant statistical difference (p<0.001). Conclusion : Students’ parallel attention to personal and professional factors in choosing the discipline compared to trivial effect of environmental factors, implies that volunteers have considered their own interests and the characteristics of the profession rather than external (improper) factors. The extensive effect of professional factors shows that it is possible to attract more interested and motivated students to this discipline via the modification of these factors.
Subcutaneous chest ports via the internal jugular vein: A retrospective study of 117 oncology patients

Purpose: To review image-guided chest port insertion using the right internal jugular vein as the access site of choice. Material and Methods: One hundred and eighteen subcutaneous chest ports were placed via the internal jugular vein in 117 patients with malignancies using both fluoroscopic and US guidance in interventional radiology suites. Results: The technical success rate was 100% with no procedural complications. Follow-up was obtained in all patients with total access days of 40,450 days (mean, 342.8 days). Premature catheter removal was required in 8 patients (6.8%, 0.20 per 1,000 access days) due to non-treatable complications: 2 catheter occlusions/malfunctions (1.7%, 0.05 per 1,000 access days), 1 catheter-related skin erosion (0.85%, 0.024 per 1,000 access days), and 5 infections (4.2%, 0.15 per 1,000 access days). Two symptomatic right upper extremity venous thromboses also occurred (1.7%, 0.05 per 1,000 access days) that were treated successfully with anticoagulation. Conclusion: Image-guided placement of internal jugular vein chest ports has a high success rate and low complication rate compared with reported series of unguided subclavian vein port insertion. The internal jugular vein should be used as the preferred venous access site compared to the subclavian vein.
Correlación de factores de riesgo y hallazgos clínicos para cáncer mamario en pre y posmenopáusicas

Introducción: El cáncer mamario es el crecimiento anormal y desordenado de células del epitelio en los lobulillos mamarios, tiene la capacidad de diseminarse a cualquier sitio del organismo. Mundialmente, su incidencia ha aumentado desde 1940, siendo la primera causa de muerte en mujeres comprendidas entre 40 y 55 años de edad. En México 45.5% se reporta en menores de 50 años. Objetivo: Comparar la correlación de severidad de factores de riesgo para cáncer mamario con hallazgos clínicos de la mama, entre premenopáusicas y posmenopáusicas. Material y métodos: Se realizó estudio observacional analítico, transversal, comparativo, a 168 mujeres, en dos grupos de pre y posmenopáusicas, entre 30 a 80 años de edad, no incluyendo aquéllas con trastorno menstrual, psiquiátrico o neoplásico. Se aplicó encuesta estructurada para factores de riesgo y guía de exploración para hallazgos de mama. Análisis con estadística descriptiva; coeficiente de correlación r de Spearman y Kruskal-Wallis con p=0.05. Resultados: Los factores de riesgo en ambos fue de 46 y 50% respectivamente; de los hallazgos clínicos, es de notar la no evidencia de lesión mamaria 56 y 66%. La correlación resultó ser débil en ambos grupos. Conclusiones: Predomina la severidad moderada de factores de riesgo para cáncer mamario en ambos grupos, mostrando una correlación débil y sin significancia estadística entre aquéllos y los hallazgos clínicos.
Research on vehicle active steering control based on linear matrix inequality and hardware in the loop test scheme design and implement for active steering

In the research process of automotive active steering control, due to the model uncertainty, road surface interference, sensor noise, and other influences, the control accuracy of the active steering system will be reduced, and the driver’s road sense will become worse. The traditional robust controller can solve the model uncertainty, pavement disturbance and sensor noise in the design process, but cannot consider the performance enough. Therefore, this article proposes an active steering control method based on linear matrix inequality. In this method, the model uncertainty, road interference, sensor noise, yaw velocity, and slip side angle tracking errors are all considered as constraint targets, respectively, so that the performance and robust stability of the active front steering system can be guaranteed. Finally, simulation and hardware in the loop experiment are implemented to verify the effect of active front steering system under the linear matrix inequality controller. The results show that the proposed control method can achieve better robust performance and robust stability.
Utility of the tumor bed marker in patients with breast cancer receiving induction chemotherapy

Purpose: Induction or neoadjuvant chemotherapy is used in patients with locally advanced breast cancer to offer a higher rate of conservative surgery. The possibility of reduction in size, even in some cases complete clinical and mammographic regression, can make the localization of the tumor bed difficult at the time of surgery. The purpose of this study was to describe our experience about the utility of US-guided implantation of a metallic marker in patients with breast cancer before induction chemotherapy. Material and Methods: Forty-three patients with 44 masses were diagnosed with percutaneous biopsy of breast carcinoma. Before beginning of the induction chemotherapy all of them were referred for metallic marker placement. A metallic harpoon was placed under US guidance. Results: One patient died during the chemotherapy. Six underwent mastectomy, and 9 still had a palpable tumor at the time of surgery. In the remaining 27 patients (with 28 lesions) pre-operative wire localization of the tumor bed was carried out: in 11 cases the harpoon was necessary for the localization of the tumor bed, in 6 the harpoon was useful, and in 11 patients the localization of the tumor could have been done without the marker. No complications were observed and the marker remained stable in all patients. Conclusion: In patients who undergo induction chemotherapy, the placement of a metallic harpoon under US guidance is a safe, simple and inexpensive technique for localization of the tumor bed previous to conservative surgery.
The value of routine MR myelography at MRI of the lumbar spine

Purpose: To determine whether a commercially available automated MR myelogram sequence improves the interpretation and diagnostic yield at MRI of the lumbar spine. Material and Methods: A total of 207 consecutive patients referred for MR examination of the lumbar spine for evaluation of low back pain or spinal radicular symptoms were included for study. All patients had initial imaging with sagittal T1-W and T2-W scans, followed by axial T2-W images. Subsequently an MR myelogram was acquired in each case in coronal, sagittal and oblique planes. MR myelogram images were evaluated initially and a diagnosis was established and recorded. Subsequently, a diagnosis was established by review of conventional images of the lumbar spine in sagittal and axial planes, in conjunction with the MR myelogram. The utility of the MR myelogram in establishing the diagnosis was graded on a 4-point scale, where grade 0 indicated that it contributed no additional information and grade 3 indicated that it was essential for diagnosis. Analysis of the additional value of myelography in patients with multilevel disease was made. Results: Primary diagnoses were disc herniation in 69 cases (33%), degenerative disc disease in 51 cases (26%), spinal stenosis in 19 cases (9%), isolated lateral recess stenosis in 5 cases (2%), or other diagnoses, including facet degeneration in 48 cases (23%). Scans were normal in 15 cases (7%). MR myelography was graded as grade 0 in 151 cases (73%), grade 1 in 44 cases (21%) and grade 2 in 12 cases (6%). In no case was MR myelography essential for diagnosis (grade 3). In patients with multilevel disease (n = 27), in 17 cases MR myelography was graded as grade 1 (63%) and in 8 cases grade 2 (30%). Conclusion: MR myelography when employed in routine practice was of limited value, assisting in establishing a diagnosis in a minority of cases (6%). The technique was of limited additional value in patients with multilevel pathology and to a lesser extent in patients with scoliosis, where it helped to establish the level most likely to account for pathology.
The clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review

Searching MEDLINE, EMBASE, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, DARE, CINAHL, ZETOC, National Research Register, ClinicalTrials.gov, the Endocrine Society's 88th annual meeting abstracts and bibliographies of included studies and relevant reviews were searched without language restrictions. The search strategy was reported. Search dates spanned 1950 to 2007. Experts were contacted to identify further published and unpublished studies. Abstracts were excluded.
Comparison of fixation and saccades identification algorithms in the eye tracking recordings for medical diagnosis

The article presents a comparative analysis of selected algorithms for eye movements identification. The analysis is based on a comparison of the classification of fixation and saccades using I-VT and I-DT algorithms. For the algorithms comparison the application that implementing the identification of eye tracking data has been developed. The results of the analysis are presented in the form of graphs.
Implementing Lean Methodology in a Power Cable Factory: A Case Study of a Low Voltage Cable

The paper discusses the effects of implementing Lean methodology in a low voltage cable factory with the goal of enhancing production and time performance. Several different tools in the Lean methodology were used in this study, including planned maintenance, autonomous maintenance, focused improvement and OEE & daily performance review. It is important to understand the current manufacturing process practiced in power cable factories. The practical effects and results of these tools are characterized in this study to help enable companies to use lean thinking. Practical implications; results indicate that applying the technique, manager can easily determine and eliminate manufacturing waster from the process. By enhancing the effectiveness of the process, they will be able to maximize resource allocation. Manufacturing sector has to validate the methodology for fruitful execution of lean technique. The adoption of Lean methodology attributed to successful execution of projects in minimizing changeover time. This implies that raw material delivery time is reduced. For instance, the use of this methodology can lead to 50 percent reduction time that is from 180 min to 90 min. Other industries such as manufacturing industry can adopt this method to reduce the production and delivery time. Pilot examples of how to use lean methods are also described so that lean methods can be applied to other machines. Finally, the paper outlines the advantages of incorporating lean methodology into a company’s projects and makes recommendations based on observations.
NEIGHBOURHOOD SAFETY AND PHYSICAL ACTIVITY OF PRESCHOOL CHILDREN IN SERBIA: MODERATING ROLE OF A CHILD'S GENDER AND PARENTS' AGE

The aim of study was to investigate the effects of parents' perceptions of neighborhood safety on outdoor physical activities of preschool children. This was investigated based on a moderating role of a child's gender and parents' age. The results showed that the association of parents’ perceptions of neighborhood safety on outdoor physical activities of children depended of the child’s sex and the parents’ age. Boys whose parents were younger and who positively assessed the neighborhood safety were more inclined to outdoor physical activities. Female children whose parents were below the average age the perceived neighborhood safety hindered frequent outdoor playing. The paper discusses practical implications of the obtained results and recommendations for future research.
Analysing Fish Behaviours Using Three-Dimensional Qualitative Trajectory Calculus 2016

Fish swim freely in water and their 3D spatial interactions may carry important information for biological study. The two-dimensional Qualitative Trajectory Calculus (QTC2D), a spatiotemporal calculus, is a method for representing and reasoning about movements of objects in a qualitative framework. This emerging technique encodes the spatial geometric relationships between distinct objects, such as machines, humans or animals. This paper presents a method for generalising QTC2D into 3D space, called 3DQTC, as a work-in-progress. The 3DQTC method is based on a geometrical analysis method of estimating the 3D orientation of �fish. Initial results indicate the potential of representing and analysing the �fish behaviours in 3D space. 3DQTC is also demonstrated as a means of extracting useful information (e.g. follow and non-follow behaviours)which cannot be achieved by QTC2D. We conclude by discussing further work and development.
N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

Background: Glutathione is an endogenous antioxidant and has a ubiquitous role in many of the body's defences. Treatment with N-acetylcysteine (NAC) has been shown to increase levels of glutathione. NAC has been proposed as a treatment for several illnesses. Objectives: The efficacy and tolerability of NAC was examined across a range of conditions to evaluate the evidence supporting the use of NAC for each indication. Methods: A literature search was conducted using PubMed. Information was also collected from other online sources including the websites of the Therapeutic Goods Administration of Australia and the FDA. Results: Reports ranged from case studies to clinical trials. There is strong evidence to support the use of NAC for the treatment of paracetamol overdose and emerging evidence suggesting it has utility in psychiatric disorders, particularly schizophrenia and bipolar disorder. NAC is safe and well tolerated when administered orally but has documented risks with intravenous administration.