Miracle-dz/UniFAR-FTUs huggingface dataset:
A preliminary framework to estimate and disclose ex-ante cost of capital for (fair) valuation

Fair-value accounting is usually seen as a rule to mark assets to market. While the market was bullish, there was little concern about the implications of a potential downside risk of fair value rules. But with the current world financial crisis triggered by US subprime loans default, pressure surged for it is simply extinction or at least for more flexibility to apply what 'fair' should really mean according to managers' judgment. Critics of fair-value (mark-to-market) accounting raise the question that in some moments market prices decouple from the 'fundamentals' and using it as the value reference can distort financial statements. In other words, they posit that market are not always efficient, markets are prone to positive and negative price bubbles. This is a preliminary work that aims to estimate ex-ante cost of capital (or expected rate of return) using market data and some parameters, like expected equity market risk-premium, its volatility and an average relative risk-aversion of a representative agent. In other words, the main objective is to establish a framework of assumptions, in order to do and disclose inherently subjective estimates of equity market portfolio (or index) ex-ante expected rate of return, in a theoretical coherent manner.
TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

TAM receptors (Tyro3, Axl, and Mer) belong to a family of receptor tyrosine kinases that have important effects on hemostasis and inflammation. Also, they affect cell proliferation, survival, adhesion, and migration. TAM receptors can be activated by the vitamin K-dependent proteins Gas6 and protein S. Protein S is more commonly known as an important cofactor for protein C as well as a direct inhibitor of multiple coagulation factors. To our knowledge, the functions of Gas6 are limited to TAM receptor activation. When activated, the TAM receptors have effects on primary hemostasis and coagulation and display an anti-inflammatory or a proinflammatory effect, depending on cell type. To comprehend the effects that the TAM receptors and their ligands have on hemostasis and inflammation, we compare studies that report the different phenotypes displayed by mice with deficiencies in the genes of this receptor family and its ligands (protein S(+/-), Gas6(-/-), TAM(-/-), and variations of these). In this manner, we aim to display which features are attributable to the different ligands. Because of the effects TAM receptors have on hemostasis, inflammation, and cancer growth, their modulation could make interesting therapeutic targets in thromboembolic disease, atherosclerosis, sepsis, autoimmune disease, and cancer.
Bovicola tibialis (Phthiraptera: Trichodectidae): Occurrence of an Exotic Chewing Louse on Cervids in North America

ABSTRACT Through a recent (2003–2007) survey of ectoparasites on hoofed mammals in western North America, a literature review, and examination of archived museum specimens, we found that the exotic deer-chewing louse, Bovicola tibialis (Piaget), is a long-term, widespread resident in the region. The earliest known collection was from Salt Spring Island, Canada, in 1941. We found these lice on the typical host, that is, introduced European fallow deer (Dama dama L.), and on Asian chital (Axis axis [Erxleben]), native Columbian black-tailed deer (Odocoileus hemionus columbianus [Richardson]), and Rocky Mountain mule deer (O. h. hemionus [Rafinesque]) × black-tailed deer hybrids. Chital and the hybrid deer are new host records. All identified hosts were known to be or probably were exposed to fallow deer. Geographic records include southwestern British Columbia, Canada; Marin and Mendocino Counties, California; Deschutes, Lincoln, and Linn Counties, Oregon; Yakima and Kittitas Counties, Washington; Curry County, New Mexico; and circumstantially, at least, Kerr County, Texas. All but the Canadian and Mendocino County records are new. Bovicola tibialis displays a number of noteworthy similarities to another exotic deer-chewing louse already established in the region, that is, Damalinia (Cervicola) sp. , which is associated with a severe hair-loss syndrome in black-tailed deer. We discuss longstanding problems with proper identification of B. tibialis, the probability that it occurs even more widely in the United States, and the prospects for it to cause health problems for North American deer. Additional information gathered since our active survey establishes further new distribution and host records for B. tibialis.
Genome Wide Analysis of Fatty Acid Desaturation and Its Response to Temperature1[OPEN]

The polyunsaturated fatty acid content of Arabidopsis seeds is determined by both cis-acting variants in FATTY ACID DESATURASE2 and an independent temperature-responsiveness locus on chromosome 2. Plants modify the polyunsaturated fatty acid content of their membrane and storage lipids in order to adapt to changes in temperature. In developing seeds, this response is largely controlled by the activities of the microsomal ω-6 and ω-3 fatty acid desaturases, FAD2 and FAD3. Although temperature regulation of desaturation has been studied at the molecular and biochemical levels, the genetic control of this trait is poorly understood. Here, we have characterized the response of Arabidopsis (Arabidopsis thaliana) seed lipids to variation in ambient temperature and found that heat inhibits both ω-6 and ω-3 desaturation in phosphatidylcholine, leading to a proportional change in triacylglycerol composition. Analysis of the 19 parental accessions of the multiparent advanced generation intercross (MAGIC) population showed that significant natural variation exists in the temperature responsiveness of ω-6 desaturation. A combination of quantitative trait locus (QTL) analysis and genome-wide association studies (GWAS) using the MAGIC population suggests that ω-6 desaturation is largely controlled by cis-acting sequence variants in the FAD2 5′ untranslated region intron that determine the expression level of the gene. However, the temperature responsiveness of ω-6 desaturation is controlled by a separate QTL on chromosome 2. The identity of this locus is unknown, but genome-wide association studies identified potentially causal sequence variants within ∼40 genes in an ∼450-kb region of the QTL.
Real time symmetrical coordinate transformation applied for detection of imbalanced fault in utility power system

This paper has investigated the possibility of a real time symmetrical coordinate transformation. Simulation is performed when it is applied for detection of imbalanced fault in utility power system. The power conditioner is required to remain connected when the fault occurs in the utility power system under certain condition. This is called as the fault ride through (FRT) ability. The most popular fault is 1 line-to-ground fault. This fault causes the imbalance voltages and currents in 3-phase power system. To optimize the output from the power conditioner of the photovoltaic system, the detection of the imbalanced condition is important factor. In this paper, the signal processing method by using the complex number algebra in real time system is shown at first. The fast detection of the imbalanced condition is verified by the computer simulations. Then the effects of the harmonic components existing in the system voltage have been investigated. The generation of the offset output and the oscillating waveforms are indicated.
Gender and Irritable Bowel Syndrome: The Male Connection

Background/Goals: Irritable bowel syndrome is more common in women; and this is generally considered to be caused by increased susceptibility. However, the opposite possibility that being male might actually protect from the disorder in some way, has largely been ignored. We have noticed that men with IBS seem to display less masculine and more feminine qualities and it was the purpose of this study to confirm or refute this clinical observation. Study: Seventy consecutive male, secondary care outpatients fulfilling the Rome 1 criteria for irritable bowel syndrome and 70 controls completed a questionnaire to determine male and female-trait scores. In addition, all subjects were assessed using the hospital anxiety depression inventory. Results: A highly significant reduction in male-trait scores was observed in the irritable bowel syndrome patients compared with controls (−10.5[−15.7,−5.2] P < 0.001). There were no differences between the groups with respect to female-trait scores. The prevalence of homosexuality was no different between patients and controls. Conclusion: Men with irritable bowel syndrome exhibit less male characteristics and it remains to be determined whether this is cause or effect. Whatever the explanation, this study adds another dimension to the role of gender in functional gastrointestinal disorders.
Researh on Network Intrusion Prevention System Based on Snort

There have been some studies highlighting Network Intrusion Prevention System on Windows platform, whereas the most current available implementations of NIPS on Windows recur to the third party firewalls lack of universality and portability. This study presents a new approach to filter the malicious network traffic by configurating IPSec automatically when detecting dangerous alert by cooperation of Snort and IPSec which is embedded in Windows 2000, Windows XP and Windows Server 2003. Firstly, the dynamic configuration and removal of IP Filter by programming are analyzed. Then the implementation of cooperation of Snort and IPSec is examined dissectionally. Finally, the comprehensive testing of the rewritten Snort is performed. The results of experiments prove this method can insulate and control dangerous data packets efficaciously without the third party firewalls and any amendments in Windows System Kernel.
Blebs in inner and outer hair cells: a pathophysiological hypothesis

Abstract Introduction: The ototoxic effects of cisplatin include loss of outer hair cells, degeneration of the stria vascularis and a decrease in the number of spiral ganglion cells. Scanning microscopy has shown balloon-like protrusions (blebs) of the plasma membrane of inner hair cells following cisplatin administration. The present study was undertaken to identify the possible role of inner and outer hair cell blebs in the pathogenesis of cisplatin-induced ototoxicity. Materials and methods: Twenty-five guinea pigs were injected with cisplatin and their hearing tested at different time-points, before sacrifice and examination with scanning electron microscopy. Results and analysis: Seven animals showed blebs in the inner hair cells at different stages. Hearing thresholds were lower in animals showing blebs. Discussion: Cisplatin seems to be able to induce changes in inner hair cells as well as in other structures in the organ of Corti. Blebbing observed in animals following cisplatin administration could play a specific role in the regulation of intracellular pressure.
Spintronic detection of interfacial magnetic switching in a paramagnetic thin film of tris(8-hydroxyquinoline)iron(III)

Dali Sun, Christopher M. Kareis , Kipp J. van Schooten, Wei Jiang, Gene Siegel, Marzieh Kavand, Royce A. Davidson, William W. Shum, Chuang Zhang, Ashutosh Tiwari, Christoph Boehme, Feng Liu, Peter W. Stephens, Joel S. Miller, Z. Valy Vardeny* Department of Physics & Astronomy, University of Utah, Salt Lake City, Utah, 84112. Department of Chemistry, University of Utah, Salt Lake City, Utah, 84112 Department of Material Science & Engineering, University of Utah, Salt Lake City, Utah 84112. Department of Physics & Astronomy, Stony Brook University, Stony Brook, NY 11794.
From one word to two words: repetition patterns on the way to structured speech

ABSTRACT This paper gives an account of the transition from one-word to multiword utterances based on the productions of one child from age 1;5.23 to 1;8.15 in spontaneous interaction with her mother. The authors' interpretation of the observed development emphasizes: (1) the initial dissociation and later co-ordination of temporal chaining of elements on the one hand and meaning-relatedness between elements on the other; and (2) the psychological importance of repetition patterns for the change from single-word functioning to meaning-related and temporally-chained multi-word utterances, i.e. utterances that show the duality of patterning characteristic of human language.
The Creation Account in Genesis 1 : 1-3 Part II : The Restitution Theory

Three views on the cosmogony of Genesis 1:1-3 have found broad acceptance in the literature on this subject: (1) the restitution theory of cosmogony, which contends that the chaos of Genesis 1:2 occurred after God had created an originally perfect universe; (2) the initially chaotic theory of cosmogony, which insists that the chaos of 1:2 occurred in connection with the original creation; and (3) the precreation chaos theory of cosmogony, which holds that the chaos of verse 2 existed before the creation mentioned in the Bible. According to the first mode of thought, chaos occurred after the original creation; according to the second mode of thought, chaos occurred in connection with the original creation; and in the third mode of thought, chaos existed before the original creation.
Internationalisation and the Role of TESOL in Tertiary Business Education

As 'internationalisation' has become a focus of policy at the University of South Australia recently, the School of International Business has been forced to question whether a minimum IELTS score of Band 6 (or its equivalent) is adequate for successful academic study. Consequently, staff from Property and Business Communication Skills (NESB) have collaborated to design a model of language, academic and cultural support to meet the sociolinguistic needs of international postgraduate students. This paper provides an overview of how a program for Master of Property students came to be developed and the possible implications for international students in other similar courses.
Sentiment as a prior for movie rating prediction

Movie ratings play an important role in tasks such as user movie recommendations, verifying the relationship between user-submitted reviews and ratings etc. The ability to predict the rating of a movie would be useful considering these aspects. In this work, firstly, we propose methods to predict the movie rating based on its summary. We then set out to use priors that are generally available with movie summaries in order to improve the accuracy. In order to achieve this, we consider the associated movie reviews as well while predicting the rating and provide insights on why this helps our models perform better. We use the review based sentiment along with the summary in order to predict the rating more accurately since the sentiment captures a lot of essential information that can aid rating prediction. We experiment with various deep learning architectures and the results show a significant accuracy boost of around 2% in most of the models which show the generalizability of our approach.
Development of sensitization versus tolerance to inhalant allergens during early life

Traditionally, the etiology of allergic respiratory disease has been viewed predominantly as an aberration of the exclusion mechanisms which normally prevent effect contact at the level of the airway mucosa, between inhaled allergens and the immune system. Allergic sensitization was thus seen as hyperresponsiveness to trivial antigens, which in normal individuals are "ignored" by the immune system. This view has changed radically over the last I 0 years, in the light of evidence from many independent sources which indicates that active immunological recognition of airborne environmental allergens is essentially universal. It is now clear that the type of immune responses in particular the type of allergen-specific T -helper (Th) cell reactivity that dominates in an individual, ultimately determines their responder phenotype. This latter conclusion derives from T -cell cloning studies in adults, which have shown that while both normal and atopic individuals contain inhalant allergenspecific Th-cell activity, Th-cell memory for individual allergens which evoke allergic responses in atopies resembles the murine Th-2 cytokine pattern ( i.e. IL4/IL-5), in contrast to the Th-1 pattern (IL-2/IFNy) in non-responding normals • These patterns of Th-cell reactivity are essentially mutually exclusive, as the cytokines produced by each Th-cell type are mutually antagonistic. These findings provide a useful and testable working model for the etiology of allergic respiratory diseases, as follows. Once immunological memory for an individual allergen in atopies is firmly consolidated as Th-2-like, the dominance of this Th-cell phenotype is reinforced at each re-exposure, until production of key cytokines such as IgE-promoting IL-4 and Eosinophilpromoting IL-5 exceed the threshold levels required to trigger clinical symptoms. Likewise, consolidation of dominant Th-1-like allergen-specific immunological memory in non-atopies (or Th-1-like memory in atopies to individual allergens to which they are non-responsive) can provide active protection against the subsequent development ofTh-2-dependent allergic sensitization.
Enterprise Information Systems and Advancing Business Solutions: Emerging Models

Madjid Tavana is a Professor of Business Systems and Analytics and the Lindback Distinguished Chair of Information Systems and Decision Sciences at La Salle University where he served as Chairman of the Management Department and Director of the Center for Technology and Management. He has been a Distinguished NASA Research Fellow at Kennedy Space Center, Johnson Space Center, Naval Research Laboratory Stennis Space Center and Air Force Research Laboratory. He was recently honored with the prestigious Space Act Award by NASA. He holds an MBA, a PMIS and a PhD in Management Information Systems and received his post-doctoral diploma in strategic information systems from the Wharton School of the University of Pennsylvania. He is the Editor-in-Chief for Decision Analytics, the International Journal of Strategic Decision Sciences, the International Journal of Enterprise Information Systems and the International Journal of Applied Decision Sciences. He has published over one hundred research papers in academic journals such as Decision Sciences, Information Systems, Interfaces, Annals of Operations Research, Omega, Information and Management, Expert Systems with Applications, European Journal of Operational Research, Journal of the Operational Research Society, Computers and Operations Research, Knowledge Management Research and Practice, Computers and Industrial Engineering, Applied Soft Computing, Journal of Advanced Manufacturing Technology and Advances in Engineering Software, among others. Madjid Tavana (La Salle University, USA)
Language mapping in children using resting-state functional connectivity: comparison with a task-based approach

Abstract. Patients with brain tumor or refractory epilepsy may be candidates for neurosurgery. Presurgical evaluation often includes language investigation to prevent or reduce the risk of postsurgical language deficits. Current techniques involve significant limitations with pediatric populations. Recently, near-infrared spectroscopy (NIRS) has been shown to be a valuable neuroimaging technique for language localization in children. However, it typically requires the child to perform a task (task-based NIRS), which may constitute a significant limitation. Resting-state functional connectivity NIRS (fcNIRS) is an approach that can be used to identify language networks at rest. This study aims to assess the utility of fcNIRS in children by comparing fcNIRS to more conventional task-based NIRS for language mapping in 33 healthy participants: 25 children (ages 3 to 16) and 8 adults. Data were acquired at rest and during a language task. Results show very good concordance between both approaches for language localization (Dice similarity coefficient=0.81±0.13) and hemispheric language dominance (kappa=0.86, p<0.006). The fcNIRS technique may be a valuable tool for language mapping in clinical populations, including children and patients with cognitive and behavioral impairments.
Remodeling of DNA replication structures by the branch point translocase FANCM

Fanconi anemia (FA) is a genetically heterogeneous chromosome instability syndrome associated with congenital abnormalities, bone marrow failure, and cancer predisposition. Eight FA proteins form a nuclear core complex, which promotes tolerance of DNA lesions in S phase, but the underlying mechanisms are still elusive. We reported recently that the FA core complex protein FANCM can translocate Holliday junctions. Here we show that FANCM promotes reversal of model replication forks via concerted displacement and annealing of the nascent and parental DNA strands. Fork reversal by FANCM also occurs when the lagging strand template is partially single-stranded and bound by RPA. The combined fork reversal and branch migration activities of FANCM lead to extensive regression of model replication forks. These observations provide evidence that FANCM can remodel replication fork structures and suggest a mechanism by which FANCM could promote DNA damage tolerance in S phase.
Single item inventory models for backorders and lost sales

the requirements for an advanced degree from the Georgia Institute of Technology, I agree that the Library of the Institute shall make it available for inspection and circulation in accordance with its regulations governing materials of this type. I agree that permission to copy from, or to publish from, this dissertation may be granted by the professor under whose direction it was written, or, in his absence, by the Dean of the Graduate Division when such copying or publication is solely for scholarly purposes and does not involve potential financial gain. It is under­ stood that any copying from, or publication of, this dis­ sertation which involves potential financial gain will not be allowed without written permission.
JTS-based static branch prediction

VLIW architectures are popular design choices in embedded computing market because of its capability of delivering performance with low power. Branch prediction plays a key role for minimizing pipeline stalls due to control hazard. Though a hardware branch predictor can result in good predictions, its HW cost often hinders it from being used in low-power VLIW architectures. On the other hand, a software branch prediction by the compiler can achieve comparable prediction quality utilizing delay slots intelligently without HW cost. In this paper, we propose a novel static branch prediction technique using jump target setting (JTS) instructions. The JTS-enabled VLIW architecture is successfully shipped in several commercial consumer electronic devices from Samsung. In our experiment using multimedia applications, the proposed branch prediction scheme outperforms the conventional static branch prediction with delay slots by 9%.
Lightweight threading with MPI using Persistent Communications Semantics.

Multi-threaded performance in MPI is of concern for future systems, particularly at Exascale, where massive concurrency will be necessary to leverage the full power of systems. While MPI provides generalized solutions and additional proposals like endpoints expand this general model, examining common use cases that have good solutions that may not be universally applicable is a viable additional approach. This paper details a new conceptual concurrency support mechanism for MPI that is applicable to a (large) subset of MPI applications. This approach is expected to provide very low overhead while still allowing for optimizations in the MPI library that are not currently possible.