Miracle-dz/UniFAR-FTUs huggingface dataset:
Accurate Estimation Of Orientation Parameters Of Uav Images Through Image Registration With Aerial Oblique Imagery

Abstract. Unmanned Aerial Vehicles (UAVs) have gained popularity in acquiring geotagged, low cost and high resolution images. However, the images acquired by UAV-borne cameras often have poor georeferencing information, because of the low quality on-board Global Navigation Satellite System (GNSS) receiver. In addition, lightweight UAVs have a limited payload capacity to host a high quality on-board Inertial Measurement Unit (IMU). Thus, orientation parameters of images acquired by UAV-borne cameras may not be very accurate. Poorly georeferenced UAV images can be correctly oriented using accurately oriented airborne images capturing a similar scene by finding correspondences between the images. This is not a trivial task considering the image pairs have huge variations in scale, perspective and illumination conditions. This paper presents a procedure to successfully register UAV and aerial oblique imagery. The proposed procedure implements the use of the AKAZE interest operator for feature extraction in both images. Brute force is implemented to find putative correspondences and later on Lowe’s ratio test (Lowe, 2004) is used to discard a significant number of wrong matches. In order to filter out the remaining mismatches, the putative correspondences are used in the computation of multiple homographies, which aid in the reduction of outliers significantly. In order to increase the number and improve the quality of correspondences, the impact of pre-processing the images using the Wallis filter (Wallis, 1974) is investigated. This paper presents the test results of different scenarios and the respective accuracies compared to a manual registration of the finally computed fundamental and essential matrices that encode the orientation parameters of the UAV images with respect to the aerial images.
Screening for cerebral aneurysm in patients with polycystic liver disease.

BACKGROUND Polycystic liver disease (PCLD) is an autosomal dominant disease characterized by multiple macrocystic lesions throughout the liver. The association between PCLD and cerebral aneurysm is well documented, and approximately 20% of patients with PCLD have demonstrable cerebral aneurysms at autopsy. The prevalence reported from autopsy series, however, may not reflect the true prevalence in patients with PCLD. We undertook this study to evaluate the prevalence and diagnosis of cerebral aneurysms in screening cerebral studies in patients with PCLD. METHODS Patients were identified by searching the hepatobiliary surgical service data base and hospital medical records. Hospital charts were reviewed to confirm presence of PCLD and to identify screening studies for cerebral aneurysms. RESULTS Ten patients with PCLD received screening studies of the cerebral vasculature during a 10 1/2-year period. One patient was found to have an asymptomatic cerebral aneurysm. A 45-year-old woman with no other significant medical history was referred for evaluation of PCLD. Screening magnetic resonance angiography (MRA) revealed a 5 mm aneurysm extending anteriorly near the origin of the right ophthalmic artery, without evidence of rupture. Cerebral angiography confirmed these findings, and the aneurysm was clipped. CONCLUSIONS Because cerebral aneurysms can be an important source of morbidity and mortality in PCLD, we recommend screening by MRA or by computed tomographic angiography (CTA) of the cerebral vasculature in all patients who have PCLD.
Comparison of Manifold Learning and Deep Learning on Target Classification

With the development of artificial intelligence, classification tasks become more and more popular, but the amount of data is growing dramatically. There are mainly two ways to deal with this problem, one is to reduce the data dimensions directly, the other one is to take advantage of all data through deep learning. In this paper, we will compare these two data processing methods. The first way is to reduce the extracted features' dimensions through manifold learning and then feed into classifiers, and the other way is to deal it directly with deep learning. The experimental results show that deep learning has a better ability than manifold learning in the classification task.
Self-Generated Versus Other-Generated Statements and Impressions in Computer-Mediated Communication

The warranting principle pertains to impression formation in Internet communication. It posits that perceivers' judgments about a target rely more heavily on information which the targets themselves cannot manipulate than on self-descriptions. Two experiments employed mock-up profiles resembling the Internet site, Facebook, to display self-generated clues and to display other-generated clues about a Facebook user. The first experiment (N = 115) tested perceptions of extraversion. Although warranting was supported, rival explanations (negativity and additivity) also pertained. The second experiment (N = 125) tested perceptions of physical attractiveness. Friends' comments overrode self-comments, supporting warranting theory exclusively. Implications concern boundary-setting research for warranting, and potential effects of social comments on a variety of new information forms.
Randomised in situ Study on the Efficacy of a Tin/Chitosan Toothpaste on Erosive-Abrasive Enamel Loss

Tin is a notable anti-erosive agent, and the biopolymer chitosan has also shown demineralisation-inhibiting properties. Therefore, the anti-erosive/anti-abrasive efficacy of the combination of both compounds was tested under in situ conditions. Twenty-seven volunteers were included in a randomised, double-blind, three-cell crossover in situ trial. Enamel specimens were recessed on the buccal aspects of mandibular appliances, extraorally demineralised (6 × 2 min/day) and intraorally treated with toothpaste slurries (2 × 2 min/day). Within the slurry treatment time, one-half of the specimens received additional intraoral brushing (5 s, 2.5 N). The tested toothpastes included a placebo toothpaste, an experimental NaF toothpaste (1,400 ppm F-) and an experimental F/Sn/chitosan toothpaste (1,400 ppm F-, 3,500 ppm Sn2+, 0.5% chitosan). The percentage reduction of tissue loss (slurry exposure/slurry exposure + brushing) compared to placebo was 19.0 ± 47.3/21.3 ± 22.4 after use of NaF and 52.5 ± 30.9/50.2 ± 34.3 after use of F/Sn/chitosan. F/Sn/chitosan was significantly more effective than NaF (p ≤ 0.001) and showed good efficacy against erosive and erosive-abrasive tissue loss. This study suggests that the F/Sn/chitosan toothpaste could provide good protection for patients who frequently consume acidic foodstuffs.
Polymorphisms in the SOD2 and HLA-DRB1 genes are associated with nonfamilial idiopathic dilated cardiomyopathy in Japanese.

To reveal genetic risk factors of nonfamilial idiopathic cardiomyopathy (IDC) in Japanese, polymorphisms in the SOD2 and HLA-DRB1 genes were investigated in 86 patients and 380 healthy controls. There was a significant excess of homozygotes for the V allele [Val versus Ala (A allele), a polymorphism in the leader peptide of manganese superoxide dismutase at position 16] of the SOD2 gene in the patients compared with the controls (87.2% versus 74.7%, odds ratio = 2.30, p = 0.013, pc < 0.03), and a significant increase in the frequency of HLA-DRB1*1401 in the patients was confirmed (14.0% vs 4.5%, odds ratio = 3.46, p = 0.001, pc < 0.03). A two-locus analysis suggested that these two genetic markers (SOD2-VV genotype and DRB1*1401) may play a synergistic role in controlling the susceptibility to nonfamilial IDC. In addition, processing efficiency of Val-type SOD2 leader peptide in the presence of mitochondria was siginificantly lower than that of the Ala-type by 11 +/- 4%, suggesting that this lower processing efficiency was in part an underlying mechanism of the association between the SOD2-VV genotype and nonfamilial IDC.
Contrast enhancement of brain tumors at different MR field strengths: comparison of 0.5 T and 2.0 T.

PURPOSE To compare the degree of MR contrast enhancement of 0.5 T and 2.0 T in various brain tumors. METHODS MR images were studied prospectively in each of 31 patients with brain tumors (11 gliomas, 6 meningiomas, 6 neurinomas, and 8 others) before and after intravenous injection of gadopentetate dimeglumine. In every patient, both 0.5-T and 2.0-T MR studies were done within 1 week. Each patient received an initial standard dose (0.1 mmol/kg) of gadopentetate dimeglumine, followed by a subsequent 0.1-mmol/kg dose (total, double dose) in MR of each field strength. MR was done before and after each injection of the contrast agent. Degree of contrast enhancement in the lesions was assessed both visually and quantitatively. RESULTS With standard-dose study, the tumor enhancement was visually stronger at 2.0 T than at 0.5 T in 9 gliomas. In extraaxial tumors there was visually no or minimal difference between 0.5 T and 2.0 T. Overall mean contrast-enhancement ratio and tumor and brain contrast-to-noise ratio were higher at 2.0 T than at 0.5 T by 53% and 108%, respectively. The double-dose study showed higher contrast-enhancement ratio and contrast-to-noise ratio than the standard-dose study at both field strengths, and the differences between 0.5 T and 2.0 T were almost similar to those of the standard-dose study. The degree of contrast enhancement with the standard dose at 2.0 T was comparable to that of the double dose at 0.5 T in most intraaxial tumors. CONCLUSION The results suggest that effect of contrast enhancement increases with the field strength. Therefore, reevaluation of optimal doses of contrast media may be needed in a variety of brain lesions at each field strength.
Optimal layout and work allocation in batch assembly under learning effect

This research investigates the effect of system's configuration (layout) and work allocation on the makespan of batches of different products characterised by significant learning. Frequently, in science-based industries the layout of the batch assembly could be relatively easily setup separately for each batch, where each batch contains different type of products. The research aims at finding guidelines for configurations and work allocations that will minimise the makespan for a given number of workers. Analytical expression of the makespan is developed and analysed.
Extrachromosomal recombination in mammalian cells as studied with single- and double-stranded DNA substrates

We have previously proposed a model to account for the high levels of homologous recombination that can occur during the introduction of DNA into mammalian cells (F.-L. Lin, K. Sperle, and N. Sternberg, Mol. Cell. Biol. 4:1020-1034, 1984). An essential feature of that model is that linear molecules with ends appropriately located between homologous DNA segments are efficient substrates for an exonuclease that acts in a 5'----3' direction. That process generates complementary single strands that pair in homologous regions to produce an intermediate that is processed efficiently to a recombinant molecule. An alternative model, in which strand degradation occurs in the 3'----5' direction, is also possible. In this report, we describe experiments that tested several of the essential features of the model. We first confirmed and extended our previous results with double-stranded DNA substrates containing truncated herpesvirus thymidine kinase (tk) genes (tk delta 5' and tk delta 3'). The results illustrate the importance of the location of double-strand breaks in the successful reconstruction of the tk gene by recombination. We next transformed cells with pairs of single-stranded DNAs containing truncated tk genes which should anneal in cells to generate the recombination intermediates predicted by the two alternative models. One of the intermediates would be the favored substrate in our original 5'----3' degradative model and the other would be the favored substrate in the alternative 3'----5' degradative model. Our results indicate that the intermediate favored by the 3'----5' model is 10 to 20 times more efficient in generating recombinant tk genes than is the other intermediate.
Release strategies in weed biocontrol: how well are we doing and is there room for improvement?

A large number of factors associated with the agent and habitat can be manipulated when making a biocontrol release. Yet, it is only recently that an experimental approach has been taken, particularly with the release of arthropod weed biocontrol agents, for example examining factors such as release size to test ideas originating from theoretical or retrospective studies. For release size, both retrospective analyses and experimental studies with arthropod agents usually show that larger releases have a higher probability of establishing. However, a limited number of large releases at a few sites also run the risk of chance extinction from locally major environmental effects. These risks can be minimized by releasing at many widespread sites, so there is often a trade-off between a few large releases and many smaller one. Unless these risks and relationships are known, a mixed strategy with arthropods, using a range of release sizes, is likely to be optimal at least at the start of a release programme. Recent theoretical attention has been applied to specific mechanisms creating lower individual fitness in small populations, termed Allee effects. It appears that Allee effects, including genetic inbreeding and problems in finding mates, may have been underestimated: They can be powerful, as witnessed by deliberate extinctions using sterile male release. Genetic issue with biocontrol releases, such as strain selection, inbreeding depression, drift and creation of laboratory-selected strains, have also received considerable, mostly theoretical, analysis. However, the actual rate of establishment success per agent species in weed biocontrol programmes is now 80–100%. These overall analyses do hide problems in establishing particular agent species: Programmes in New Zealand targeting ‘recalcitrant’ environmental weeds have been hampered by partial or complete failure to get potentially critical agent species established. A case study of heather beetle in New Zealand is used to illustrate the frustrations and research challenges in a release programme.
New Step-Up/Step-Down DC–AC Converter

This paper introduces a new dc-ac converter with the feature that it produces an instantaneous output voltage higher or lower than the input dc voltage without an intermediate power stage or transformers. This feature is provided by using one switching cell including two switches, two diodes, one inductor, and one capacitor on each inverter leg. Validating the theoretical analysis, a prototype was designed, built, and tested for an output rated power of 1 kW, a dc input voltage of 96Vdc, and output voltage of 110 Vrms. Furthermore, the fundamental output frequency was established at 60 Hz and the switching frequency at 20 kHz.
ERK1/2抑制剂AZD8330对Burkitt淋巴瘤细胞株Raji细胞的作用及其机制研究

目的 探讨细胞外信号调节激酶1/2（ERK1/2）抑制剂AZD8330对Burkitt淋巴瘤细胞株Raji细胞的作用及其机制。 方法 Raji细胞用不同浓度的AZD8330进行处理；采用CCK-8检测细胞存活率；流式细胞术检测细胞凋亡情况；实时定量PCR法检测Bcl-2、Bcl-xl、caspase-3和血管内皮生长因子(VEGF）mRNA表达；Western blot法检测Bcl-2、Bcl-xl、caspase-3、磷酸化(p)-ERK1/2蛋白表达。 结果 1.00 µmol/L的AZD8330处理24、48和72 h后细胞存活率分别为(62.09±0.86）%、(50.06±1.33）%和(39.13±2.34）%，差异有统计学意义（P值均<0.05）；0.10、1.00、10.00 µmol/L的AZD8330分别处理Raji细胞24、48和72 h，Raji细胞发生凋亡，凋亡率呈时间和剂量依赖性，差异有统计学意义（P值均<0.05）；随着浓度增加和时间延长，Bcl-2、Bcl-xl、VEGF mRNA表达降低，caspase-3 mRNA表达升高，差异有统计学意义（P值均<0.05）；同时，Bcl-2、Bcl-xl、p-ERK1/2蛋白表达明显受抑制，而caspase-3蛋白表达增强。 结论 AZD8330可能通过抑制ERK1/2通路相关基因和蛋白的表达而诱导Burkitt淋巴瘤Raji细胞凋亡，抑制其增殖。
Nucleo-mitochondrial interactions in yeast mitochondrial biogenesis.

For what once were probably free-living aerobic bacteria, mitochondria show a surprising degree of domestication in terms of their dependence on the genetic system of the cells in which they reside. In most organisms, only a handful of the hundred or so mitochondrial proteins are encoded by mitochondrial DNA (mtDNA). The remainder, including most of the components of the mitochondrion’s own genetic system, are encoded by nuclear genes, which also specify all other enzymes necessary for the synthesis, import, processing and modification of these proteins and associated lipid components. The assembly of a functional mitochondrion is possibly one of the most complex logistic exercises faced by the eukaryotic cell. In a facultative anaerobic organism like the yeast Saccharomyces cerevisiae, which is capable of tailoring the level of mitochondrial biosynthesis to its specific needs in response to its environment, several hundred nuclear genes are likely to be involved in one way or another with mitochondrial biogenesis.
Indian Parents' Perspective towards Brand Loyalty and Kids’ Wear Safety

Parental care is an essential part of human nature. Parents have the most important role for ensuring the safety and wellbeing of their children. Children of all ages are at risk of injury from wearing defective clothing. Product safety refers to the reduction in the probability that use of a product will result in injury, death or negative consequences to the people who are going to use it. Customer satisfaction and brand loyalty is an evolving trend that is considered an essential concern for which the business firms are very sensitive. Study has been conducted to know whether Indian parents will be loyal to the brands who will provide safe garments for the kids. In this study, the data has been collected with the help of structured questionnaire from 1235 parents from Bengaluru, India. The respondents were selected through stratified random sampling. This study proved that kidswear safety and customer loyalty have strong effect. Irrespective of gender, education, profession and family income, parents are ready to loyal with the brand which is going to provide safe garments for their kids.
he perils of using annual all-cause mortality data to estimate pandemic nfluenza burden

Measuring the burden of historic pandemics is not straightforward and often must be based on suboptimal mortality data. For example, the critical 1918 pandemic global burden estimate was based on excess in annual all-cause mortality – calculated as the difference between deaths during 1918–1920 and the surrounding 3-year periods. One intriguing result was a ∼40-fold between-country variation in pandemic mortality burden: ∼0.2% of Danes died, compared to ∼8% of populations in some Indian provinces (Murray et al., 2006 [16]). Using the same methodology and data source we explore the robustness of this methodology for different age-groups. For infants the country estimates varied 100-fold, from 15 to 1500 excess deaths/10,000 population, while for adults ≥45 years estimates ranged from −70 to 170/10,000 population. In contrast, estimates for children, 1–14 years, and adults aged 15–44 years, were far more stable. We next used detailed mortality data from Copenhagen to compare such estimates to the more precise estimates obtained from monthly mortality time series data and respiratory deaths. We found that the all-cause annual method substantially underestimated due to an unexplained depression in all-cause mortality in Denmark in 1918 and deaths caused by other epidemic diseases during the baseline periods. We conclude that country estimates for infants and older adults were highly variable by the Murray method due to substantial variability in annual all-cause mortality. A more precise 1918 pandemic burden estimate would be gotten from either focusing analysis on persons age 1–44 who suffered 95% of all pandemic deaths and had a substantial rise over their baseline mortality level, or if possible focus analysis on annual respiratory deaths. For less severe pandemics, including the ongoing 2009 H1N1 pandemic, the use of all-cause mortality data requires careful consideration of excess deaths in defined pandemic periods and a focus on age groups known to be at risk. © 2011 Elsevier Ltd. All rights reserved.
The p53 mutation “gradient effect” and its clinical implications

The p53 tumor suppressor‐signaling pathway is inactivated in most human cancers. Depending on how p53 is targeted during tumorigenesis impacts whether partial or full tumor suppressor activity is lost. The degree of remaining p53 activity, if any, intuitively impacts the tumor phenotype. This review focuses on recent findings from human cancer studies and genetically engineered mouse models to highlight a p53 functional “gradient effect” and its clinical implications. J. Cell. Physiol. 213: 370–373, 2007. © 2007 Wiley‐Liss, Inc.
Care of acute myocardial infarction in the coronary care units of Piedmont in 2007: results from the ‘PRIMA_sweet’ region-wide survey

Background The treatment of acute myocardial infarction (AMI), both with ST-segment elevation [ST-elevation myocardial infarction (STEMI)] and non-ST-segment elevation [non-ST-elevation myocardial infarction (NSTEMI)], is evolving in Piedmont, with an increase in interventional procedures and hub-and-spoke networks. This new region-wide survey provides updated assessment of the management of STEMI and unprecedented data on NSTEMI. Methods In 30 coronary care units in Piedmont, all patients with AMI symptoms of duration less than 48 h, between January and March 2007, were included. Results Of 921 patients, 447 had STEMI and 474 NSTEMI. Diabetes was present in 35% and chronic kidney disease in 38%. Hospital mortality was 4.7% [95% confidence interval (CI) 3.3–6.1]: age 75 years or older, Killip class higher than 1 and known diabetes or abnormal blood glucose on admission were multivariate predictors. Thrombolysis and primary percutaneous transluminal coronary angioplasty (pPTCA) were performed in 17.6 and 53.1% of 391 patients, respectively, with STEMI of 12 h or less, and 29.3% had no reperfusion therapy, notably 52% of patients aged 75 years or older and 51% of those reaching non-24/24 h interventional centres. Mortality after pPTCA was 2.5% and onsite door-to-balloon time was less than 90 min in 67.5%. Overall mortality after STEMI was 5.4% (95% CI 3.2–7.6). In NSTEMI, use of antithrombotic treatments was extensive, but invasive treatment within 72 h was limited to 8% of patients in centres without interventional facilities and independent of patient's risk profile. Mortality after NSTEMI was 4.0% (95% CI 2.2–5.8) and was predicted by both the Global Registry of Acute Coronary Events risk score and diabetes. Conclusion There is room for improvement in the treatment of AMI in our region, with more extensive use of reperfusion therapy in STEMI, especially in the elderly, and early revascularization and optimal medical treatment in higher-risk NSTEMI.
Zumbis vs sedentários: quem irá vencer? Avaliando a usabilidade do aplicativo Zombie's, run!

E sabido que a pratica de atividades fisicas e um fator importante e essencial na vida de uma pessoa, sendo recomendada inclusive, para prevencao de doencas hipocineticas. Dessa forma, o uso de aplicativos para dispositivos moveis, como os de incentivo a pratica de corrida e caminhada, tem se tornado um aliado para aqueles que buscam deixar de lado o sedentarismo. Neste trabalho, realizamos uma inspecao de usabilidade, por meio de avaliacao heuristica, do aplicativo Zombie's Run! , que tem como objetivo apoiar a atividade de corrida e caminhada, buscando atraves da tematica de zumbis, incentivar a pratica continua do exercicio fisico. Para complementar este estudo, foram utilizados questionarios para avaliar a usabilidade do aplicativo, de acordo com a opiniao de usuarios corredores, que relataram sua primeira experiencia de uso. O objetivo principal deste trabalho, portanto, vai alem da analise de usabilidade da aplicacao: tambem buscamos analisar se a tematica moderna e os fatores de gamificacao reunem as caracteristicas necessarias para atrair jovens (pessoas com idade inferior aos 30 anos) a pratica de corrida e a posterior manutencao do habito.