Miracle-dz/UniFAR-FTUs huggingface dataset:
Beyond Opinion Mining - How can Automatic Online Opinion Analysis Help in Product Design?

The rapid development of WWW, information technology and e-commerce has made the Internet forums, eopinion portals and personal blogs widely accessible to consumers. As a result, nowadays it has become extremely popular for consumers to share their experience, point out their preferences and concerns with respect to a specific product on Web. These online customer reviews possess vital information that product designers can gain insights of their customers and products, and make improvements accordingly. However, the sheer amount of data, their distributed locations and the inherent ambiguity of human language have challenged designers greatly. In this paper, we aim to outline an intelligent system that is able to first automatically gather global online reviews with respect to certain products interested, identify the product features and customer requirements, and most importantly relates them to the product’s engineering characteristics through quality function deployment (QFD), a tool that is widely used by product designers in the customer-driven design paradigm. Meanwhile, we also highlight the challenges and relevant research issues in order to fulfil such an ambition. As a pioneer study, we believe that this research will greatly help designers in the era of global competition and e-commerce.
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation

Colorectal carcinoma RKO cells expressing reduced levels of the RNA‐binding protein HuR (ASHuR) displayed markedly reduced growth. In synchronous RKO populations, HuR was almost exclusively nuclear during early G1, increasing in the cytoplasm during late G1, S and G2. The expression and half‐life of mRNAs encoding cyclins A and B1 similarly increased during S and G2, then declined, indicating that mRNA stabilization contributed to their cell cycle‐regulated expression. In gel‐shift assays using radiolabeled cyclin RNA transcripts and RKO protein extracts, only those transcripts corresponding to the 3′‐untranslated regions of cyclins A and B1 formed RNA–protein complexes in a cell cycle‐dependent fashion. HuR directly bound mRNAs encoding cyclins A and B1, as anti‐HuR antibodies supershifted such RNA–protein complexes. Importantly, the expression and half‐life of mRNAs encoding cyclins A and B1 were reduced in ASHuR RKO cells. Our results indicate that HuR may play a critical role in cell proliferation, at least in part by mediating cell cycle‐dependent stabilization of mRNAs encoding cyclins A and B1.
Does female education explain the disparity in the use of antenatal and natal services in Nigeria? Evidence from demographic and health survey data.

BACKGROUND Nigeria is among the countries with a high number of annual maternal deaths partly due to low utilization of maternal health services (MHS). OBJECTIVE This study aimed to explore whether there is an association between women's level of education and the appropriate use of antenatal and delivery services. METHOD A quantitative cross-sectional study was used to analyze the Nigerian Demographic and Health Survey (NDHS) data. Information from 33,385 women aged 15 - 49 years was analyzed using Bivariate Pearson Chi square test and multiple logistic regressions. RESULTS Education is statistically associated with the number of antenatal clinic visits made (AOR = 3.208; CI 2.875 - 3.578; p < .0001) and the place of delivery (AOR = 2.009; CI 1.449 - 2.785; p < .0001) even after controlling for availability of skilled health workers, parity, income, religion, age and distance. CONCLUSION A long term investment in girls' education will improve income, interaction with health care providers, level of autonomy to seek and pay for appropriate MHS and ultimately use of MHS and positive pregnancy outcomes.
Light Therapy for Seasonal and Nonseasonal Depression: Efficacy, Protocol, Safety, and Side Effects

Abstract Bright light therapy for seasonal affective disorder (SAD) has been investigated and applied for over 20 years. Physicians and clinicians are increasingly confident that bright light therapy is a potent, specifically active, nonpharmaceutical treatment modality. Indeed, the domain of light treatment is moving beyond SAD, to nonseasonal depression (unipolar and bipolar), seasonal flare-ups of bulimia nervosa, circadian sleep phase disorders, and more. Light therapy is simple to deliver to outpatients and inpatients alike, although the optimum dosing of light and treatment time of day requires individual adjustment. The side-effect profile is favorable in comparison with medications, although the clinician must remain vigilant about emergent hypomania and autonomic hyperactivation, especially during the first few days of treatment. Importantly, light therapy provides a compatible adjunct to antidepressant medication, which can result in accelerated improvement and fewer residual symptoms.
Complete Genome Sequence of Streptococcus suis Serotype 3 Strain ST3

ABSTRACT Streptococcus suis is a zoonotic pathogen causing economic loss in the swine industry and is also a threat to human health. To date, the mechanism of pathogenesis is not fully understood. Here, we report the complete genome sequence of S. suis strain ST3 of serotype 3, which provides opportunities to reveal genetic basis of infection of S. suis non-serotype 2 strains.
The North American Indian Trickster

One of the most perplexing problems confronting those who wish to understand the myths and folk tales of the North American Indians is the figure of the "trickster," who is also the creative transformer of the world and the heroic bringer of culture. This "trickster-transformer-culture hero" (or "trickster-fixer," for short) is a problem because he combines in one personage no less than two and sometimes three or more seemingly different and contrary roles. Oftentimes he is the maker of the earth and/or he is the one who changes the chaotic myth-world into the ordered creation of today; he is the slayer of monsters, the thief of daylight, fire, water, and the like for the benefit of man; he is the teacher of cultural skills and customs; but he is also a prankster who is grossly erotic, insatiably hungry, inordinately vain, deceitful, and cunning toward friends as well as foes; a restless wanderer upon the face of the earth; and a blunderer who is often the victim of his own tricks and follies. What kind of logic combines all these disparate elements into one mythical personality? The figure who embraces all these traits of character is known throughout Indian North America by various names. Over much
Investigation on Construction of Network Course and Its Optimization Model

As a newly developed course, the network course (NC) plays very important role in modern teaching and education. Using the theory of grey linear programming, the optimization model of minimizing the cost and optimizing the NC resource is setup. Adapting the grey interval, the variables have a wide range of interval regions to take effect on the cost and the useful resource. The example shows that, if the link in the process of the NC arrangement and course resource allocation is reasonable, the cost in developing the NC will be lowered and the resource will be valuably allocated.
Sensitive Detection of Borrelia burgdorferi Sensu Lato DNA and Differentiation ofBorrelia Species by LightCycler PCR

ABSTRACT In order to differentiate species within the Borrelia burgdorferi sensu lato complex, LightCyler PCR and melting-curve analysis of the amplicons of two genes with intraspecies variability, the p66 gene and the recA gene, were performed. It was demonstrated that nested LightCycler PCR amplification ofp66 is more sensitive in the detection of borrelia DNA than amplification of the recA gene. B. burgdorferisensu stricto could be differentiated from Borrelia gariniiand Borrelia afzelii by melting-curve analysis of thep66 gene amplicon. B. garinii could be differentiated from B. afzelii and B. burgdorferi sensu stricto by melting-curve analysis of therecA gene amplicon. Therefore, the PCRs complement each other in subtyping different Borrelia species, and combined LightCycler PCR and melting-curve analysis of both target genes is a rapid method to distinguish the three species of B. burgdorferi sensu lato.
Sexually dimorphic alterations of brain cortical dominance in rats prenatally exposed to TCDD

Sexually dimorphic patterns of cortical lateralization are documented extensively in both human and animal brains. Male rats tend to exhibit pronounced right hemisphere dominance compared with females, whereas females typically exhibit more diffuse lateralization patterns and greater left hemisphere bias compared with males. Prenatal TCDD (2,3,7,8 tetrachlorodibenzo‐p‐dioxin) exposure produces demasculinization of male offspring sexual behavior. In previous studies, we showed a reversal of cortical dominance in rats after prenatal TCDD exposure on gestational day 18 (GD 18). The current study aimed to determine the nature of changes observed in rats exposed to TCDD on GD 8. In addition, locomotor activity was measured in male and female offspring on postnatal day (PND) 30, 60 and 90. Pregnant females were given, via gavage, a single dose of 0, 20, 60 or 180 ng kg−1 TCDD on GD 8. Cortical depth measurements were taken in selected brain regions in offspring 3 months old that had been exposed to the 180 ng kg−1 dose. Areas 2, 3, 17, 18a and 39 at bregmas −1.8, −3.8 and −5.8 were analyzed by quantifying digitized, enhanced images produced by a photomicroscope fitted with a special color camera. In both male and female offspring, cortical thicknesses in control brains exceeded those of exposed brains. In several brain areas of male offspring exposed to TCDD, right hemispheric dominance reversed to left hemispheric dominance. Female offspring brains showed a contrary move towards right hemisphere dominance. Motor activity in juvenile and mature animals did not differ among dose groups. These data demonstrate that prenatal exposure to TCDD reduces cortical thickness and alters the normal pattern of cortical asymmetry, a finding consistent with the sexually dimorphic behavioral effects induced by this agent. Copyright © 2002 John Wiley & Sons, Ltd.
Comparison of characteristics and therapeutic efficacy in rheumatoid arthritis patients treated by rheumatologists and those treated by orthopedic surgeons under a team medicine approach at the same institute

The treatment of rheumatoid arthritis (RA) has improved dramatically with the advent of the latest generation of disease-modifying antirheumatic drugs. Despite these advances, in some patients inflammation is not diminished sufficiently to prevent irreversible musculoskeletal damage, thereby necessitating surgical intervention to reduce pain and improve function. For RA treatment, Japanese orthopedic surgeons also prescribe medication. In this study, we examined whether this Japanese system is effective for RA treatment. We analyzed the clinical condition of RA patients treated by rheumatologists and those treated by orthopedists in a linked registry study using information from a large observational cohort of RA patients followed every half year from 2000 to 2010 (the IORRA cohort). Two groups of patients were compared: patients treated by rheumatologists (rheumatologic group) and patients treated by orthopedists (orthopedic group). The results revealed that patients in the orthopedic group were older, more likely to be female, and had a longer disease duration than patients in the rheumatologic group. The proportion of patients with a history of joint surgery was also much higher in the orthopedic group than in the rheumatologic group. The average scores on the Japanese version of the Health Assessment Questionnaire, and the remission ratio determined using a Boolean-based definition gradually increased from 2000 until 2010, and these findings were consistently better in the rheumatologic group than in the orthopedic group. These data suggest that patients treated primarily by orthopedists are more likely to have long-standing RA compared to patients treated by rheumatologists. Therefore, it is critical for rheumatologists and orthopedists to complement each other medically in the treatment of RA patients.
Food groups and renal cell carcinoma: A case–control study from Italy

Although nutrition and diet have been related to renal cell carcinoma (RCC), the role of specific foods or nutrients on this cancer is still controversial. We evaluated the relation between a wide range of foods and the risk of RCC in an Italian case–control study including 767 patients (494 men and 273 women) younger than 79 years with incident, histologically confirmed RCC, and 1,534 controls (988 men and 546 women) admitted to the same hospitals as cases for a wide spectrum of acute, non‐neoplastic conditions, not related to long term diet modifications. A validated and reproducible food frequency questionnaire, including 78 foods and beverages, plus a separate section on alcohol drinking, was used to assess patients' dietary habits 2 years before diagnosis or hospital admission. Multivariate odds ratios (OR) were obtained after allowance for energy intake and other major confounding factors. A significant direct trend in risk was found for bread (OR = 1.94 for the highest versus the lowest intake quintile), and a modest excess of risk was observed for pasta and rice (OR = 1.29), and milk and yoghurt (OR = 1.27). Poultry (OR = 0.74), processed meat (OR = 0.64) and vegetables (OR = 0.65) were inversely associated with RCC risk. No relation was found for coffee and tea, soups, eggs, red meat, fish, cheese, pulses, potatoes, fruits, desserts and sugars. The results of this study provide further indications on dietary correlates of RCC, and in particular indicate that a diet rich in refined cereals and poor in vegetables may have an unfavorable role on RCC. © 2006 Wiley‐Liss, Inc.
AMERICAN SOCIETY OF ANESTHESIOLOGISTS CLASSIFICATION OF PHYSICAL STATUS AS A PREDICTOR OF WOUND INFECTION

Background: Wound infection occurs when bacterial contamination overcomes the hosts’ defences against bacterial growth. Wound categories are a measurement of wound contamination. The American Society of Anesthesiologists (ASA) classification of physical status may be an effective indirect measurement of the hosts’ defence against infection. This study examines the association between the ASA score of physical status and wound infection.
Analyse De L'Effet Des Impots Differes Sur Le Contenu Informationnel Du Resultat : Cas Des Firmes Utilisant Les Normes Internationales Et Les Normes Americaines

L'objectif de ce papier est d'analyser l'effet des impots differes sur le contenu informationnel du resultat pour deux echantillons de firmes se referant aux normes IAS/IFRS et aux US GAAP sur une periode de dix ans (1994-2003). En effet, c'est a partir de 1999 que le traitement selon les normes internationales (IAS 12 revisee) est le meme que celui des US GAAP. Les tests realises permettent d'analyser l'effet de l'adoption de l'IAS 12 revisee sur le contenu informationnel du resultat et sur la convergence entre les referentiels comptables international et americain. Globalement, les resultats obtenus montrent que le traitement des impots differes selon l'IAS 12 revisee a contribue au rapprochement entre les deux referentiels : international et americain.
Structured Sparsity in Natural Language Processing: Models, Algorithms and Applications

This tutorial will cover recent advances in sparse modeling with diverse applications in natural language processing (NLP). A sparse model is one that uses a relatively small number of features to map an input to an output, such as a label sequence or parse tree. The advantages of sparsity are, among others, compactness and interpretability; in fact, sparsity is currently a major theme in statistics, machine learning, and signal processing. The goal of sparsity can be seen in terms of earlier goals of feature selection and therefore model selection (Della Pietra et al., 1997; Guyon and Elisseeff, 2003; McCallum, 2003). This tutorial will focus on methods which embed sparse model selection into the parameter estimation problem. In such methods, learning is carried out by minimizing a regularized empirical risk functional composed of two terms: a "loss term," which controls the goodness of fit to the data (e.g., log loss or hinge loss), and a "regularizer term," which is designed to promote sparsity. The simplest example is L1-norm regularization (Tibshirani, 2006), which penalizes weight components individually, and has been explored in various NLP applications (Kazama and Tsujii, 2003; Goodman, 2004; Gao, 2007). More sophisticated regularizers, those that use mixed norms and groups of weights, are able to promote "structured" sparsity: i.e., they promote sparsity patterns that are compatible with a priori knowledge about the structure of the feature space. These kind of regularizers have been proposed in the statistical and signal processing literature (Yuan and Lin, 2006; Zhao et al., 2009; Kim et al., 2010; Bach et al., 2011) and are a recent topic of research in NLP (Eisenstein et al., 2011; Martins et al, 2011, Das and Smith, 2012). Sparsity-inducing regularizers require the use of specialized optimization routines for learning (Wright et al., 2009; Xiao, 2009; Langford et al., 2009). The tutorial will consist of three parts: (1) how to formulate the problem, i.e., how to choose the right regularizer for the kind of sparsity pattern intended; (2) how to solve the optimization problem efficiently; and (3) examples of the use of sparsity within natural language processing problems.
Improved lumped-pi circuit model for bulk current injection probes

In this work, a lumped-parameter circuit model of injection probes for bulk current injection (BCI) is derived and discussed. The model is extracted from scattering parameter experimental measurements carried out with the probe mounted on an ad hoc calibration fixture, ideally working as an electrically-short transmission line. A circuit model of the overall calibration fixture is used to de-embed setup-related effects in order to identify the circuit structure of the probe model. The proposed model extends those developed in the past by accounting for frequency dependent inductive coupling (dispersion and losses of the ferrite), capacitive coupling between the probe and the wiring under test, and setup related effects.
A Fair Peer Selection Algorithm for an Ecommerce-Oriented Distributed Recommender System

Most of the existing recommender systems nowadays operate in a single organizational base, and very often they do not have sufficient resources to be used in order to generate quality recommendations. Therefore, it would be beneficial if recommender systems of different organizations can cooperate together sharing their resources and recommendations. In this paper, we propose a preliminary design of a distributed recommender system that consists of multiple recommender systems from different organizations. Moreover, a peer selection algorithm is also presented that allows a recommender system peer to select a set of other peers to cooperate with. The proposed selection mechanism not only ensures a high degree of user satisfaction to the generated recommendation, it also makes sure that every peer has been fairly treated and studied. The paper also further points out how the proposed distributed recommender system and the peer selection algorithm can provide a solution to the problem of resource lacking (e.g. cold start problem) and also enables recommender systems to provide recommendations with better novelty and quality to users.
Characterization of Cdk9 T‐loop phosphorylation in resting and activated CD4+ T lymphocytes

The cellular kinase complex P‐TEFb is composed of Cdk9 and cyclin T, and it is required for expression of most protein‐coding genes by RNAP II. Cdk9 has been shown recently to be activated in cis by autophosphorylation of Thr186 in its T‐loop. Using a phosphospecific Cdk9 antibody, we examined the level of Cdk9 T‐loop phosphorylation in resting and activated CD4+ T lymphocytes. Cdk9 T‐loop phosphorylation was found to be low‐to‐undetectable in resting CD4+ T lymphocytes, and upon activation by distinct stimuli, there is a rapid (<1 h) increase in pCdk9 that does not require protein synthesis. The low level of Cdk9 T‐loop phosphorylation was not to be a result of the absence of an associated regulatory cyclin partner. These observations suggest that autophosphorylation of the Cdk9 T‐loop is repressed in resting CD4+ T lymphocytes. The low level of T‐loop phosphorylation in resting cells is also reflected in a low level of phosphorylation of Ser2 in the carboxyl terminal domain of RNAP II, suggesting that lack of Cdk9 T‐loop autophosphorylation may limit RNAP II elongation in quiescent CD4+ T lymphocytes.
Measuring Quality of Pharmacotherapy for Depression in a National Health Care System

Objectives:This article examines the use of antidepressant medication in the treatment of major depression in the Department of Veterans Affairs (VA) during the 2001 fiscal year and considers the relationship of patient, drug, provider, and facility to adherence to medication treatment guidelines. Methods:Prescription drug records for all VA outpatients diagnosed with major depression (International Classification of Diseases, 9th edition, code 296.2 or 296.3) were collected for October 2000 through September 2001. Indicators were constructed that noted whether patients newly treated with antidepressants (ie, with no prescription in the previous 8 weeks) received at least 180 days (continuation phase) of antidepressant drug treatment (84- and 140-day measures were also considered). Logistic regression with and without center fixed effects and generalized estimation equations were used to identify patient, drug, and facility characteristics that were associated with these treatment quality indicators. Results:Of the 27,713 patients in the final sample, 54% received at least 181 days of treatment. This is higher than recent rates reported by Health Employer Data and Information Set (HEDIS) for the general population, although our measures and those used by HEDIS are not exactly the same. Women, married patients, older patients, and whites were more likely than others to have higher-quality antidepressant drug treatment. Contrary to previous research, we find few significant differences among specific antidepressant agents prescribed in this large sample. Comorbid substance abuse was associated with fewer days of treatment, whereas other psychiatric comorbidities increased the length of treatment. We found few differences resulting from provider type. Although significant differences among facilities were found in the unadjusted rates (similar to those used by HEDIS), these diminished greatly after controlling for relevant covariates. Conclusions:In the nation's largest mental health system, quality of pharmacotherapy for depression, at least by one standard measure, is relatively good. We found the specific antidepressant drug used has little impact on quality. In considering differences among facilities, we found that it is critical to control for relevant patient characteristics.