Miracle-dz/UniFAR-FTUs huggingface dataset:
Collaborative value creation and learning in innovation projects for a circular city

Over the last decade, the concept of a circular economy, an industrial economy that is restorative or regenerative by intention and design, has gained increased attention of policy makers, industry and academics. Recently the number of innovation projects, set up by local governments, communities, non-governmental organizations and businesses, to experiment with new sustainable technologies for a circular city, has increased substantially. This paper aims to explore how in this emerging field different stakeholders collaboratively create value and develop a viable sustainable business model. We do so by building on business model literature and literature on innovation networks and combining these with insights on value outcomes and learning from strategic management. For this study we take a qualitative research approach, building on four innovation projects for a circular city, characterized by collaboration of a wide variety of stakeholders, each being initiated and coordinated by a different stakeholder type. The findings show an emphasis on technical and organizational learning, influencing expected and unexpected value outcomes. The main contribution of this paper is a conceptual framework to analyse value creation and capture within the context of open partnerships through different learning types. Learning proves to be an effective mechanism in innovation networks to create and capture more economic, environmental and social value then initially aimed for.
Hyperthermic radiosensitization of synchronous Chinese hamster cells: relationship between lethality and chromosomal aberrations.

Synchronous Chinese hamster cells in vitro were obtained by mitotic selection. The cells were heated at 45.5°C for 4 min in mitosis, 11 min in G1, or 7 min in S sphase and then X-irradiated immediately thereafter. Colony survival from heat alone was 0.30 to 0.45, and the frequency of chromosomal aberrations induced by heat was 0.00, 0.14, or 0.97 for heat treatments during M, G1, or S, respectively. As shown previously, lethality from hyperthermia alone is due to chromosomal aberrations only when the cells are heated during S phase. The log survival $(D_{0}^{\sim}=80\ \text{rad})$ and aberration frequency curves for cells irradiated during mitosis were linear, and the only effect of hyperthermia was to shift the curves in accord with the effect from heat alone. Thus, hyperthermia did not radiosensitize the mitotic cells. The cells irradiated in G1 were more resistant $(D_{0}^{\sim}=100\ \text{rad})$ than those irradiated in mitosis, and the survival and aberration.
Spironolactone with ACE inhibitor is effective in gross hematuria caused by nephroptosis

Abstract Gross hematuria caused by nephroptosis is difficult to treat and sometimes requires surgical treatment. We experienced a case of a 64‐year‐old woman with gross hematuria due to nephroptosis and glomerular thin basement membrane that showed remission of hematuria with the blockade of the renin‐angiotensin‐aldosterone system with an angiotensin‐converting enzyme inhibitor and spironolactone.
Landfill leachate characterization for simulation of biological treatment with Activated Sludge Model No. 1 and Activated Sludge Model No. 3

Landfill leachates can be characterized correctly in terms of Activated Sludge Model No. 1 (ASM1) and Activated Sludge Model No. 3 (ASM3) variables. The wastewater characterization of leachate from a Luxembourg landfill was based on a physical‐chemical method combined with a BOD analysis for the COD fractions and on standard analysis for forms of nitrogen. The results show important differences compared with municipal wastewater. High amounts of organic matter with low biodegradability were found, as well as a high concentration of ammonium nitrogen. Based on average values, a generic ASM characterization is proposed for landfill leachates. It can be directly employed in the early stages of the simulation of landfill leachate treatment with activated sludge models.
Heart rate variability during high ambient heat exposure.

INTRODUCTION This study observed heart rate variability (HRV) measured in order to detect the changes in sympathovagal activity during high ambient (74 degrees C) temperature. HRV is a measure of heart rate (HR) fluctuations around the mean HR and has been used to indicate the balance between parasympathetic and sympathetic function of the autonomic nervous system in medicine and exercise, but not in extreme environments. METHODS There were 10 healthy male subjects who wore Polar HR monitors (PE 5000) during a 15-min exposure (74.3 +/- 5.9 degrees C). RESULTS HR increased significantly (p < 0.05) from 66.5 bpm pre-exposure to 106.0 bpm during exposure to the dry heat. A significant decrease in parasympathetic drive was indicated by: (1) a reduction of 89.1 +/- 31.3% in the proportion of interval differences between two normal R-R intervals that were in excess of 50 ms in length (pNN50); (2) an 83.4 +/- 7.0% decrease in the root mean square of successive R-R differences (RMSSD); and (3) an 82.7 +/- 11.4% decrease in the normalized high-frequency (HF norm) values. An increase in a sympathetic drive was indicated by a significant increase in: (1) the normalized low-frequency (LF norm) values of (84.5 +/- 19.4%); and (2) the LF:HF ratio (10.9 +/- 10.8%). DISCUSSION The results from this study show that exposure to high ambient temperature produces a significant increase in HR through an increase in sympathetic and decrease in parasympathetic drive.
A UNIVERSIDADE E SUA RESPONSABILIDADE SOCIAL

O artigo apresenta enfoques de diferentes autores sobre a responsabilidade social da Universidade. Enfatiza sua importância na formacao integral do individuo para a sociedade do futuro, devendo constituir-se num espaco social que privilegie a criacao e a instigacao da criatividade, preparando, assim, o homem para a vida num mundo em constante transformacao mediante a ativacao de sua capacidade reflexiva, buscando configurar novas respostas as necessidades da sociedade. A Universidade como a instituicao que, aberta para o dialogo com seu entorno, devera buscar solucoes concretas para os problemas do presente e do futuro, mediante a formacao de profissionais de acordo com a real demanda social, da investigacao direcionada para a interdisciplinaridade e a integracao do cientifico com o humanistico, numa efetiva vivencia da solidariedade social.
Alternative splicing: global insights

Following the original reports of pre‐mRNA splicing in 1977, it was quickly realized that splicing together of different combinations of splice sites – alternative splicing– allows individual genes to generate more than one mRNA isoform. The full extent of alternative splicing only began to be revealed once large‐scale genome and transcriptome sequencing projects began, rapidly revealing that alternative splicing is the rule rather than the exception. Recent technical innovations have facilitated the investigation of alternative splicing at a global scale. Splice‐sensitive microarray platforms and deep sequencing allow quantitative profiling of very large numbers of alternative splicing events, whereas global analysis of the targets of RNA binding proteins reveals the regulatory networks involved in post‐transcriptional gene control. Combined with sophisticated computational analysis, these new approaches are beginning to reveal the so‐called ‘RNA code’ that underlies tissue and developmentally regulated alternative splicing, and that can be disrupted by disease‐causing mutations.
Ab initio molecular-dynamics study of defects on the reconstructed Si(001) surface.

We present a new defect model for the reconstructed Si(001) surface. Ab initio molecular-dynamics simulations at finite temperature show the existence of interstitial dimers which are recessed from the surface. These dimers and adjacent on-surface dimers are both symmetric. The possibility that missing dimer vacancies observed by scanning tunneling microscopy contain these new surface defects is pointed out.
On the power of active relay attacks using custom-made proxies

A huge number of security-relevant systems nowadays use contactless smart cards. Such systems, like payment systems or access control systems, commonly use single-pass or mutual authentication protocols to proof the origin of the card holder. The application of relay attacks allows to circumvent this authentication process without needing to attack the implementation or protocol itself. Instead, the entire wireless communication is simply forwarded using a proxy and a mole allowing to relay messages over a large distance. In this paper, we present several relay attacks on an ISO/IEC 14443-based smart card implementing an AES challenge-response protocol. We highlight the strengths and weaknesses of two different proxy types: an NFC smart phone and a dedicated custom-made proxy device. First, we propose a “three-phones-in-the-middle” attack that allows to relay the communication over more than 360 feet (110 meters). Second, we present a custom-made proxy that solves major relay-attack restrictions that apply on almost all NFC smart phones, for example, cloning of the victim's UID, adaption of low-level protocol parameters, direct request for Waiting Time Extensions, or active modifications of the messages. Finally, we propose an attack that allows to induce single bit faults during the anticollision of the card which forces the reader to re-send or temporarily stall the communication which can be exploited by attacks to gain additional relay time.
Amortissement non-linéaire des structures sandwichs à matériau d'âme en fibres enchevêtrées

Les structures sandwichs sont largement utilisees dans le domaine de l’aeronautique et de l’espace du fait de leur bon rapport rigidite sur masse. Cependant, leur amortissement doit etre ameliore pour le confort des utilisateurs et la durabilite des structures. L’objectif de cette these est d’etudier l’amortissement apporte a une structure sandwich par l’utilisation d’un materiau d’âme recemment developpe. Ce materiau est fabrique a base de fibres de carbone enchevetrees, reticulees avec de la resine epoxy. Le materiau enchevetre-Reticule est d’abord etudie seul. Les mesures experimentales montrent un comportement dependant de l’amplitude et de l’historique de sollicitation, et independant de la frequence. Un modele d’hysteresis est developpe pour decrire les boucles contrainte-Deformation mesurees. L’etude theorique d’une structure a un degre de liberte permet de detailler l’effet des differentes composantes de ces boucles sur la reponse dynamique. Le materiau est ensuite inclus dans une poutre sandwich. Un modele de vibrations de poutres sandwichs en flexion est propose pour inclure un comportement non-Lineaire dissipatif du materiau d’âme. Une etude experimentale est menee sur des poutres sandwichs, montrant un amortissement tres superieur a celui apporte par un materiau d’âme classique comme le nid d’abeille. Les simulations realisees avec le modele de poutre sandwich et le modele d’hysteresis permettent de bien capturer les phenomenes non-Lineaires observes. A la fin de l’etude, une utilisation mixte d’un materiau d’âme en nid d’abeille et d’un materiau d’âme enchevetre-Reticule est proposee afin d’obtenir un bon amortissement pour un faible ajout de masse.
Investigation on the effect of impedance changes in broadband antennas with varying antenna height on radiated emission measurement below 1 GHz

According to the standard method for calibration of receive antennas to be used in radiated emission measurement below 1 GHz, the sensitivity of receive antenna is defined as a free-space antenna factor obtained by applying a given correction factor to a near free-space factor that is determined by horizontally polarized antenna calibration at a 2 m antenna height. In actual radiated emission measurement performed while varying the receive antenna height, however, the sensitivity of receive antenna varies with antenna impedance changes at different antenna heights. In this situation, the authors measured how the antenna impedance changes with the antenna height and examined how such impedance changes affect radiated emission measurement results, using biconical, log-periodic dipole, and hybrid antennas under test that are typical below 1 GHz. The authors also studied on a method to estimate an antenna height free from antenna impedance changes and suitable for obtaining free-space factors.
Reversal of Rocuronium-induced Neuromuscular Block by the Selective Relaxant Binding Agent Sugammadex: A Dose-finding and Safety Study

Background: Sugammadex (Org 25969) forms a complex with steroidal neuromuscular blocking agents, thereby reversing neuromuscular block. This study investigated the dose–response relation, safety, and pharmacokinetics of sugammadex to reverse rocuronium-induced block. Methods: Twenty-seven male surgical patients aged 18–64 yr were randomly assigned to receive placebo or sugammadex (0.5, 1.0, 2.0, 3.0, or 4.0 mg/kg) for reversal of 0.6 mg/kg rocuronium–induced neuromuscular block. Anesthesia was induced and maintained using intravenous fentanyl and propofol. Neuromuscular function was assessed using acceleromyography. Sugammadex or placebo was administered at reappearance of T2 of the train-of-four. The primary efficacy variable was the time required for recovery to a train-of-four ratio of 0.9. Results: Sugammadex decreased median recovery time in a dose-dependent manner from 21.0 min in the placebo group to 1.1 min in the group receiving 4.0 mg/kg sugammadex. Doses of sugammadex of 2.0 mg/kg or greater reversed rocuronium-induced neuromuscular block within 3 min. A median of 59–77% of sugammadex was excreted unchanged in the urine within 16 h, mostly in the first 8 h. Sugammadex increased the proportion of the rocuronium dose excreted unchanged in the urine (from a median of 19% in the placebo group to 53% in the 4.0-mg/kg group within 16 h). Sugammadex was safe and well tolerated. No evidence of recurarization was observed in any patient. Conclusion: At doses of 2.0 mg/kg or greater, sugammadex safely reversed 0.6 mg/kg rocuronium–induced neuromuscular block in a dose-dependent manner. Sugammadex enhanced renal excretion of rocuronium and was excreted unchanged by the kidneys.
Caveolar Endocytosis and Microdomain Association of a Glycosphingolipid Analog Is Dependent on Its Sphingosine Stereochemistry*

We have previously shown that glycosphingolipid analogs are internalized primarily via caveolae in various cell types. This selective internalization was not dependent on particular carbohydrate headgroups or sphingosine chain length. Here, we examine the role of sphingosine structure in the endocytosis of BODIPY™-tagged lactosylceramide (LacCer) analogs via caveolae. We found that whereas the LacCer analog with the natural (d-erythro) sphingosine stereochemistry is internalized mainly via caveolae, the non-natural (l-threo) LacCer analog is taken up via clathrin-, RhoA-, and Cdc42-dependent mechanisms and largely excluded from uptake via caveolae. Unlike the d-erythro-LacCer analog, the l-threo analog did not cluster in membrane microdomains when added at higher concentrations (5–20 μm). In vitro studies using small unilamellar vesicles and giant unilamellar vesicles demonstrated that l-threo-LacCer did not undergo a concentration-dependent excimer shift in fluorescence emission such as that seen with BODIPY™-sphingolipids with natural stereochemistry. Molecular modeling studies suggest that in d-erythro-LacCer, the disaccharide moiety extends above and in the same plane as the sphingosine hydrocarbon chain, while in l-threo-LacCer the carbohydrate group is nearly perpendicular to the hydrocarbon chain. Together, these results suggest that the altered stereochemistry of the sphingosine group in l-threo-LacCer results in a perturbed structure, which is unable to pack closely with natural membrane lipids, leading to a reduced inclusion in plasma membrane microdomains and decreased uptake by caveolar endocytosis. These findings demonstrate the importance of the sphingolipid stereochemistry in the formation of membrane microdomains.
Grid Impedance Monitoring System for Distributed Power Generation Electronic Interfaces

This paper proposes a grid impedance monitoring system for distributed power generation electronic interfaces. The system estimates the grid equivalent impedance and voltage source from the voltage measurements performed at the point of common coupling. The estimation algorithm is based on a recursive least-squares algorithm implemented in the complex field. Simultaneously, the system evaluates the quality of the estimation, minimizing its influence on the grid and detecting islanding situations. The proposed system performance has been evaluated under experimental testing.
Active Learning for Software Defect Prediction

SUMMARY An active learning method, called Two-stage Active learning algorithm (TAL), is developed for software defect prediction. Combining the clustering and support vector machine techniques, this method improves the performance of the predictor with less labeling e ﬀ ort. Experiments validate its e ﬀ ectiveness. key words: machine learning
The effect of input current ripple on the photovoltaic panel efficiency

This paper presents the effect of the input current ripple on the photovoltaic source efficiency. The input and output current can be either continuous or discrete, with or without ripple, giving either continuous or discrete energy flow hence affecting the input source efficiency or the output load application. This paper considers the influences of the converter input current ripple on the photovoltaic module and the loss of power extracted, in conjunction with converter efficiency, thus losses in the overall system efficiency. With input current (or voltage) ripple, there is no maximum power point; instead, there is maximum power track or locus curve. When the input current ripple reduces to zero, the maximum power curve becomes a point, specifically the DC maximum power point.
Particle filter based robust simultaneous localization and map building

Robust simultaneous localization and map building (SLAM) is a key issue for mobile robot in presence of faults. In the paper, an adaptive particle filter is designed to achieve robust SLAM for wheeled mobile robot when the robot is subjected to faults such as sensor faults and wheel slippage. Firstly, the kinematics models of wheeled mobile robots and the measurement models of laser range finder are derived, five kinds of residual features are extracted and faults are detected according residual features, and the proposal distribution is adaptively constructed according to residual features. Secondly, an adaptive mutation scheme is designed to recover the diversity of the particles after resampling stage. Lastly, the presented method is testified in a real mobile robot.
Profiling of Microbial Community Diversity in Vermifiltration of Different Earthworm Abundances by PCR-DGGE

In three vermifiltration column disposing residual sludge, where there were different densities of earthworm (0 g/L, 40 g/L, 60 g/L), microbial community diversity were studies by PCR-DGGE. Results showed that different vermifiltration had different microbial diversity. Shannon-Weaver index analysis revealed that Hs in column 2 and column 3 with earthworm were higher than that in column 1. In depth distribution, microbial diversity reduced gradually on the whole in the three vermifiltration column. These findings indicate that earthworm occurrence could enhance microbial diversity, and improve the growth environment for bacterium. However, their relation might be complex, and still remain to be studied in detail.
Control of Improved Full-Bridge Three-Level DC/DC Converter for Wind Turbines in a DC Grid

This paper presents an improved full-bridge three-level (IFBTL) dc/dc converter for a wind turbine in a dc grid by inserting a passive filter into the dc/dc converter to improve the performance of the converter. The passive filter can effectively reduce the voltage stress of the medium frequency transformer in the IFBTL dc/dc converter. A modulation strategy, including two operation modes, is proposed for the IFBTL dc/dc converter. Then, a voltage balancing control strategy is proposed for the IFBTL dc/dc converter. Furthermore, the control of the wind turbine based on the IFBTL dc/dc converter in a dc-grid system is presented. Finally, a small-scale IFBTL dc/dc converter prototype was built and tested in the laboratory, and the results verify the theoretical analysis.
Evidence That Cut Optic Nerve Fibers in a Frog Regenerate to Their Proper Places in the Tectum

The frog's retina projects into the superficial neuropil of the opposite tectum in four functionally different layers of terminals. Each layer displays a continuous map of the retina in terms of its particular function. The four maps are in register. The fourth-dimensional order is reconstituted after section and regeneration of the optic fibers.
Energy Drinks: ¿Ayudan, Perjudican o Hiperenergizan?

• Algunas energy drinks contienen hierbas, aminoacidos, proteinas, y otras sustancias, usualmente en pequenas cantidades, que probablemente no producen ningun efecto sobre el rendimiento. El contenido de alguno de estos productos puede producir absorcion ineficiente de los fluidos y nutrientes desde el intestino, con la posibilidad de producir distress gastrointestinal. Muchas energy drinks son muy costosas y por su composicion no son convenientes para ser utilizadas por los atletas Los atletas deberian ser educados e informados acerca de estos productos y orientados hacia otras comidas y fluidos que no posean riesgos potenciales para la salud.
Software Reliability: Principles and Practices

Deals constructively with recognized software problems. Focuses on the unreliability of computer programs and offers state-of-the-art solutions. Covers--software development, software testing, structured programming, composite design, language design, proofs of program correctness, and mathematical reliability models. Written in an informal style for anyone whose work is affected by the unreliability of software. Examples illustrate key ideas, over 180 references.
Modeling the Temporal Evolution of Postoperative Complications

Post-operative complications have a significant impact on patient morbidity and mortality; these impacts are exacerbated when patients experience multiple complications. However, the task of modeling the temporal sequencing of complications has not been previously addressed. We present an approach based on Markov chain models for characterizing the temporal evolution of post-operative complications represented in the American College of Surgeons National Surgery Quality Improvement Program database. Our work demonstrates that the models have significant predictive value. In particular, an inhomogenous Markov chain model effectively predicts the development of serious complications (coma longer than a day, cardiac arrest, myocardial infarction, septic shock, renal failure, pneumonia) and interventional complications (unplanned re-intubation, longer than 2 days on a ventilator and bleeding transfusion).