Miracle-dz/UniFAR-FTUs huggingface dataset:
Osteochondritis dissecans of the talar dome: Evaluation of bone viability with dynamic gadolinium-enhanced MR imaging in comparison with dynamic bone scintigraphy

Objective. To determine the viability of osteochondritis dissecans (OD) in the talar dome with dynamic (dyn) contrast-enhanced MR imaging using dynamic (dyn) scintigraphy as the standard of reference. Materials and methods. Dyn MR images and bone scintigraphy scans of 9 consecutive patients, evaluated between January 1998 to December 2000, were reviewed. MR imaging was performed using a fast gradient echo technique with acquisition of a single slice section positioned over the area of OD. Three-phase bone scintigraphy with administration of 600 MBq 99Tc HDP and dyn image acquisition for 3 minutes and after 3 hours post injection was performed. Signal intensity (SI) and radioactivity curves were compared between the two techniques. Results. Eight of the nine cases showed good correlation between the findings of dyn MR and dyn scintigraphy. In seven of the eight patients there was contrast enhancement and radioactivity uptake in the central area of the OD lesion consistent with good vascularization of the lesion. No enhancement or activety was seen in one patient. In the other case dyn MR imaging showed no central enhancement of the OD lesion, while three-phase bone scintigraphy depicted uptake in the OD lesions. Conclusion. The findings suggest that dyn MR imaging in comparison with dyn scintigraphy better determines the viability of OD lesions. It is our belief that due to the relative poor spatial resolution of scintigraphy central necrosis is not visualised. An additional advantage of dyn MR imaging is that the procedure is easily performed following conventional MR imaging without exposing the patient to ionizing radiation.
LASER-AIDED CERAMIC ORTHODONTIC BRACKETS DEBONDING EFFECTS ON SHEAR BOND STRENGTH AND ENAMEL SURFACE

The objective of the present study is to assess the effects of ( Er:YAG ) laser debond ing of ceramic brackets on the shear bond strength h and the amount of adhesive resin remnant and ceramic cracks caused by removing the adhesive remnant . Materials and Methods: Sample of the study consisted of 50 upper first premolars extracted for orthodontic reasons to which ceramic brackets were attached using ( Light Bond resilience orthodontic products Inc, USA ) . The sample randomly divided into two equal groups . The ER:YAG was applied for 6 seconds using the scanning method on one of these groups using the ( KaVoKEY LASER HI 1243 ) device . later all the specimens were debounded and tested on a testing machine ( Tecnotest ) in Tishreen University . The amount of adhesive remnant was evaluated with adhesive remnant index ( AR1 ) . After de-bounding of the brackets tungsten carbide bur was used to remove adhesive remnant in all specimens , examination of the buccal surface of all specimens to evaluate enamel cracks caused by removing the adhesive remnant post debonding of ceramic brackets statistical calculations were conducted for search using a program ( SPSS Version 13,0 ) Results : Application of ( ER: YAG ) laser thermally softened adhesive resin structure , lowered the bonding resistance of ceramic brackets and enabled their debonding ,decrease of shear bond strength values (P<0.05 ) . Laser debonding caused a significant decrease in the frequency of enamel cracks compared to conventional debonding . There are no statistically significant differences in ARI scores between laser group and the control group . Conclusion : W power Er:YAG laser application with the scanning method to polycrystalline ceramic brackets demonstrated lower bond strengths and decrease of enamel cracks during the debonding procedure .
Input/Output Logic With a Consistency Check - the Case of Permission

In Input/output (I/O) logic, one makes a distinction between three kinds of permission, called negative, positive static and positive dynamic permission. They have been studied semantically and axiomatically by Makinson and van der Torre in the particular case where the underlying I/O operation for obligation is one of the standard systems. In this paper, we investigate what happens when the underlying I/O operation is one of the constrained I/O operations recently introduced by Parent and van der Torre. Their distinctive feature is two-fold. First, they are not closed under logical consequence. Second they have a built-in consistency check, which ﬁlters out excess outputs and allows them to properly deal with contrary-to-duty reasoning. The main contribution of this paper is the characterization of the positive static permission with a set of rules, called subverse rules. Due to the fact that the studied logics are diﬀerent from the original framework, although the proof of the characterization result is similar to the original one, it still includes novel arguments. This is the deﬁnition of a ﬁrst positive permission proof system for constrained output.
Structured differentiable models of 3D scenes via generative scene graphs

Generative approaches to 3D scene perception and physical reasoning are increasingly common [1, 2, 3, 4, 5, 6, 7]. There is a widespread need for scene models that can incorporate planar and pointwise contacts between physical objects, and ensure that objects do not inter-penetrate [8]. Generic priors on 6DOF poses — and bottom-up neural networks that de-render images into scenes [6] — typically violate these constraints.
Personnel Management, Motivation and Productivity in Nigeria’s Public Service

It is often said that personnel management is the livewire of every organization. This assertion is evidently true and has full expression in the Nigeria‟s private sector that is structured for maximum productivity. This accounts for the massive improvement in the service delivery currently witnessed in the private sector. But unfortunately, the opposite is the case in the public sector where productivity and efficient service delivery is almost none existence. The reason for this abysmal performance of public servants is still a matter of scholarly debate. Some argue that the absence of employee motivation and poor personnel management were responsible for the deep-rooted unproductive and inefficiency evident in the public service. In order to provide satisfactory explanations to why most Nigerian public servants fail to bring innovation and creativity to their jobs, at least an understanding of their work condition and welfare packages is necessary. It has been acknowledged therefore that most workers in Nigeria only commits to their jobs just for their daily survival and never dedicated to making meaningful impact in the society. This is partly because of poor personnel management system and lack of motivation. Despite the fact that rewards and incentives are found to stimulate innovation, creativity and productivity amongst workers, however, it is regrettable that the management structures in the Nigerian workspace particularly in government establishments have not been able to integrate the employee motivation schemes into the public service. The paper therefore seeks to dialectically analyze the deficiencies inherent in Nigeria‟s public service, using the “university employees” as the basis for understanding the linkages between staff motivation and productivity. In addition, the paper argues that Nigeria‟s public service including the university system since inception is conspicuously underperforming in terms of quality service delivery, innovation and creativity. Drawing from the Vroom‟s Expectancy Theory of motivation and qualitative analytical techniques, the paper concludes that the university employees are highly unlikely to put in their best at work except the authorities adopts both the intrinsic and extrinsic approaches to personnel management, which could potentially motivate employees for outstanding creative performances.
3-MANIFOLDS WITH ABELIAN EMBEDDINGS IN S

We consider embeddings of 3-manifolds in S4 such that each of the two complementary regions has an abelian fundamental group. In particular, we show that an homology handle M has such an embedding if and only if π1(M)′ is perfect, and that the embedding is then essentially unique. Every integral homology 3-sphere embeds as a topologically locally flat hypersurface in S, and has an essentially unique “simplest” such embedding, with contractible complementary regions. For other 3-manifolds which embed in S, the complementary regions cannot both be simply-connected, and it not clear whether they always have canonical “simplest” embeddings. If M is a closed hypersurface in S = X ∪M Y then H1(M ;Z) ∼= H1(X;Z)⊕H1(Y ;Z), and so embeddings such that each of the complementary regions X and Y has an abelian fundamental group might be considered simplest. We shall say that such an embedding is abelian. Although most 3-manifolds that embed in S do not have such embeddings, this class is of particular interest as the possible groups are known, and topological surgery in dimension 4 is available for abelian fundamental groups. Homology 3-spheres have essentially unique abelian embeddings (although they may have other embeddings). This is also known for S × S and S/Q(8), by results of Aitchison (published in [21]) and Lawson [16], respectively. In Theorems 10 and 11 below we show that if M is an orientable homology handle (i.e., such that H1(M ;Z) ∼= Z) then it has an abelian embedding if and only if π1(M) has perfect commutator subgroup, and then the abelian embedding is essentially unique. (There are homology handles which do not embed in S at all! ) The 3-manifolds obtained by 0-framed surgery on 2-component links with unknotted components always have abelian embeddings, and the complementary regions for such embeddings are homotopy equivalent to standard 2-complexes. These shall be our main source of examples. In particular, we shall give an example in which X ' Y ' S ∨ S, but the pairs (X,M) and (Y,M) are not homotopy equivalent. We do not yet have examples of a 3-manifold with several inequivalent abelian embeddings. The first two sections fix our notation, recall some earlier work, and give some results on homotopy equivalences. In §3 we define the notions of abelian and nilpotent embeddings. Sections 4–6 consider abelian embeddings of 3-manifolds M with torsion free homology (i.e., H1(M ;Z) ∼= Z , where β ≤ 4 or β = 6). In §7 we consider briefly some embeddings of rational homology spheres. In particular, we shall show that ten 3-manifolds with elementary amenable fundamental group have abelian embeddings. The question remains open for one further such 3-manifold. In §8 we give some simple observations on the possible homotopy types 1991 Mathematics Subject Classification. 57N13.
Improvement of ADHD-Related Symptoms in School Age Children and Young Adults with Autism via a Smartglasses-Based Socio- Emotional Coaching Aid

Introduction People with autism spectrum disorder (ASD) commonly experience ADHD-related symptoms, including hyperactivity, inattention, and impulsivity. A third of people on the spectrum may be diagnosed with attention hyperactivity deficit disorder (ADHD). These dually diagnosed individuals often face barriers to ADHD treatment. Non-pharmacological technology-aided tools for hyperactivity and inattention in people with ASD are being developed, although research into their efficacy and safety remains limited. This preliminary report describes the changes to ADHD-related symptoms in children and adults with ASD after use of the Brain Power Autism System (BPAS), a behavioral and social communication aid for ASD based on augmentedreality smartglasses. Methods Eight children and adults with ASD (M:F ratio of 7:1, mean age 15 years, range 11.7-20.5 years) were recruited through a web-based research signup form. Four of these participants had a history of ADHD. The baseline score on the hyperactivity subscale of the Aberrant Behavioral Checklist (ABC-H), a measure of hyperactivity, inattention, and impulsivity, determined their classification into a high ADHDrelated symptom group (n = 4, ABC-H ≥ 13) and a low ADHD-related symptom group (n = 4, ABC-H < 13). All participants attended a coaching session with BPAS, where they used smartglasses-based social communication and behavioral modules while interacting with their caregiver. Caregiver-reported ABC-H scores were then calculated at 24and 48hours post-session. Results All eight participants were able to complete the coaching session. ABC-H scores were lower postintervention for most participants at 24 hours (n = 6, 75%), and for all participants at 48 hours (n = 8, 100%). At 24-hours post-session, average ABC-H scores decreased by 54.4% in high ADHD symptom group and by 20% in the low ADHD symptom group. At 48-hours post-session ABC-H scores compared to baseline decreased by 56.4% in the high ADHD symptom group and by 66.3% in the low ADHD symptom group. Conclusion Use of the BPAS, a smartglasses-based behavioral and social communication aid for school-aged children and young adults with ASD, was associated with reduced ADHD-related symptom burden. While there may be a placebo effect when using novel technology, this consideration should be tempered with knowledge that many people with ASD have been noted to react negatively to novel experiences and transitions. The observed effects are likely to be temporary, and further research is required to understand clinical importance of these observed changes. Future research on longer-term monitoring with a larger sample size is recommended. IN REVIEW Interactive Journal of Medical Research
Wound Stress Induced Secondary Metabolites in Passiflora foetida: Exploration of Antimicrobial Compounds

DOI: 10.21276/sjmps.2018. 4.5. 21 Abstract: The wound stress is applied to leaves of P. foetida and ethyl actetate extracts is optimized using mobile phase: ethyl acetate: chloroform: glacial acetic acid: benzene (25:15:2:10) and TLC bioautographic depict two antimicrobial compounds at Rf 0.46 and 0.73. The extract shows antimicrobic activity 12 mm against S. aureus at 5 mg/ml and 14 mm against E. coli at 10 mg/ml. Their HR-LCMS chromatogram elucidates the structure of two possible antimicrobial compounds as nitrofurazone (RT: 0.644 min) or 4-tridecynoic acid (RT 7.616 min) and dihydrodeoxystreptomycin (RT:9.22min). The HPLC-DAD detected dihydrodeoxystreptomycin at 254 nm and ibuprofen at 220 nm. The GCMS confirmed 4-chloro 7-nitrobenzofurazan (RT: 18.39), methyl jasmonate (RT: 18.84), 10.03 PPM and 12-hydroxy dodecanoic acid (RT: 23.79), 82.65 PPM in 96 extract. These compound's viz 4-tridecynoic acid and dihydrodeoxystreptomycin, ibuprofen, 4-chloro 7-nitrobenzofurazan, methyl jasmonate and 12-hydroxy dodecanoic acid could be possible raised as antimicrobial drugs in pharmaceutical industries.
Ensuring Secure Data Communication Cloud Environment

—Cloud storage enables users to remotely store their data and enjoy the on-demand high quality cloud applications without the burden of local hardware and software management. Though the benefits are clear, such a service is also relinquishing users’ physical possession of their outsourced data, which inevitably poses new security risks toward the correctness of the data in cloud. In order to address this new problem and further achieve a secure and dependable cloud storage service, a flexible distributed storage integrity auditing mechanism, utilizing the homomorphism token and distributed erasure-coded data. The proposed design allows users to audit the cloud storage with very lightweight communication and computation cost. The auditing result ensures strong cloud storage correctness guarantee.
The Second-Order Cone Quadratic Eigenvalue Complementarity Problem

We investigate the solution of the Second-Order Cone Quadratic Eigenvalue Complementarity Problem (SOCQEiCP), which has a solution under reasonable assumptions on the matrices included in its definition. A Nonlinear Programming Problem (NLP) formulation of the SOCQEiCP is introduced. A necessary and sufficient condition for a stationary point (SP) of NLP to be a solution of SOCQEiCP is established. This condition indicates that, in many cases, the computation of a single SP of NLP is sufficient for solving SOCQEiCP. In order to compute a global minimum of NLP for the general case, we develop an enumerative method based on the Reformulation-Linearization Technique and prove its convergence. For computational effectiveness, we also introduce a hybrid method that combines the enumerative algorithm and a semi-smooth Newton method. Computational experience on the solution of a set of test problems demonstrates the efficacy of the proposed hybrid method for solving SOCQEiCP.
The Variation of DNA Cytosine Methylation in Wheat Genome Induced by~(60)Co-γ Rays

Mutation technique has played an important role in wheat improvement. Nuclear irradiation may affect genome stability by altering DNA methylation patterns( including hyper-methylation and hypo-methylation). In this study,seeds of wheat variety Jing 411 were irradiated by60Co-γ rays with the dose of 100 Gy and 150 Gy,respectively. Variation of DNA cytosine methylation in seedling leaf and root were detected by methylation sensitive amplification polymorphism( MSAP). The results showed that seedling height and root length were significantly inhibited after60Co-γ ray irradiation. DNA cytosine methylation in leaves and roots was altered after60Co-γ ray treatment. Compared with the control,the methylation variations in leaves and roots were different. The relative level of methylation in leaves was decreased,but increased in roots,indicating tissue specificity. The rates of demethylation variation in leaves at both dosages were higher than those of methylation,and it was opposite in roots. At different sites,the variations of methylation patterns were different. At CG and CNG sites of leaves,demethylation rates were higher than those of methylation at both dosages. In root,demethylated variation rate of CNG sites were lower than the corresponding methylation sites. Under 100 Gy,the demethylation variation rate at CG sites is higher than the methylation variation rate of the corresponding sites, and it is consistent with methylation patterns variation of leaves. under 150 Gy, the methylation variation rate at CG sites is higher than the demethylation variation rate of the corresponding sites. The result indicated that the variation of methylation pattern,induced by different dosage of60Co-γ rays,even in the same organization and same site was different.
Pairing Bacteroides vulgatus LPS Structure with Its Immunomodulatory Effects on Human Cellular Models

The gut microbiota guide the development of the host immune system by setting a systemic threshold for immune activation. Lipopolysaccharides (LPSs) from gut bacteria are able to trigger systemic and local proinflammatory and immunomodulatory responses, and this capability strongly relies on their fine structures. Up to now, only a few LPS structures from gut commensals have been elucidated; therefore, the molecular motifs that may be important for LPS–mammalian cell interactions at the gut level are still obscure. Here, we report on the full structure of the LPS isolated from one of the prominent species of the genus Bacteroides, Bacteroides vulgatus. The LPS turned out to consist of a particular chemical structure based on hypoacylated and mono-phosphorylated lipid A and with a galactofuranose-containing core oligosaccharide and an O-antigen built up of mannose and rhamnose. The evaluation of the immunological properties of this LPS on human in vitro models revealed a very interesting capability to produce anti-inflammatory cytokines and to induce a synergistic action of MD-2/TLR4- and TLR2-mediated signaling pathways.
Rôle différentiel des cellules épithéliales intestinales et pulmonaires dans le recrutement des cellules Th17 vers les sites de réplication du virus de l'immunodéficience humaine de type 1

L’infection a VIH-1 est associee a une forte depletion des lymphocytes T CD4+ a polarisation Th17 au niveau des tissus lymphoides associes aux muqueuses intestinales (GALT, gut-associated lymphoid tissues). Ceci conduit a la translocation microbienne, qui est une cause d’activation immunitaire chronique et de progression de la maladie. Les cellules epitheliales (CE) jouent un role critique dans le maintien de l’integrite et de l’homeostasie au niveau des muqueuses intestinales via le recrutement des cellules de l’immunite innee (e.g., neutrophiles) et adaptative (e.g., cellules Th17). Les neutrophiles produisent des molecules antivirales (e.g., defensines-) et ont la capacite de limiter la replication virale au niveau des muqueuses. Les cellules Th17 jouent un double role lors de l’infection a VIH. Elles contribuent d’une part a la defense contre differents pathogenes opportunistes en augmentant, via la production d’IL-17, la capacite des CE a attirer les cellules Th17 et les neutrophiles. D’autre part, les cellules Th17 jouent un role deletere en tant que cibles de replication virale et sources de cytokines pro-inflammatoires. La frequence des cellules Th17 est diminuee dans les GALT mais pas dans les poumons des patients infectes par le VIH, suggerant qu’il existe des mecanismes differents par lesquels les cellules Th17 sont recrutees vers ces sites anatomiques. Nous avons teste l’hypothese selon laquelle le VIH interfere avec la capacite des CE intestinales et non pas pulmonaires a produire des chimiokines (CK) responsables de l’attraction des cellules Th17 et des neutrophiles. Nous avons demontre que les CE intestinales et pulmonaires produisent des CK specifiques pour les cellules Th17 (CCL20) et les neutrophiles (CXCL8) en reponse a des stimuli pro-inflammatoires tels que l’IL-1 et le TNF-. Le TNF- agit en synergie avec l’IL-17, un « signal de danger » recemment identifie, et augmente la capacite des CE intestinales mais pas pulmonaires a produire la chimiokine CCL20. Cette synergie s’explique par l’augmentation preferentielle de l’expression du recepteur a l’IL-17 a la surface des CE intestinales suite a la stimulation par le TNF-. L’exposition au VIH n’affecte pas la production de CCL20 et de CXCL8 par les CE intestinales, mais altere la capacite des CE alveolaires a produire ces chimiokines en accord avec la permissivite selective de ces dernieres a l’infection par le VIH. En conclusion, nos resultats demontrent que (i) le VIH n’interfere pas directement avec la capacite des CE intestinales a recruter des cellules Th17 et des neutrophils et que (ii) la production de CCL20 par ces cellules est dependantes de la synergie entre le TNF- et l’IL-17. Ainsi, la depletion des cellules Th17 et la penurie en IL-17 dans les GALT des sujets infectes pourrait causer de facon preferentielle des alterations fonctionnelles au niveau des CE intestinales, se traduisant par l’alteration du recrutement des cellules Th17 en reponse au CCL20.
Average case analysis of a k-CNF learning algorithm

Author(s): Hirschberg, Daniel S. ; Pazzani, Michael J. | Abstract: We present an approach to modeling the average case behavior of an algorithm for learning Conjunctive Normal Form (CNF, i.e., conjunctions of disjunctions). Our motivation is to predict the expected error of the learning algorithm as a function of the number of training examples. We evaluate the average case model by comparing the error predicted by the model to the actual error obtained by running the leaming algorithm, and show how the analysis can lead to insight into the behavior of the algorithm and the factors that affect the error.