Miracle-dz/UniFAR-FTUs huggingface dataset:
A Study of profile of glaucoma in eastern UP

Objective: To study the profile of glaucoma patients in Eastern UP. Method: Prospective cross sectional study includes 193 cases of age group (more than 30 years). Both male and female were included. Results: The total number of 193 cases was studied. Out of these 106 (54.9%) were male and 87 (45.07%) were female with a male female ratio was 1.21. Primary glaucoma was more common than secondary glaucoma. Among primary glaucoma, primary narrow angle glaucoma (44.4%) was more common followed by primary open angle glaucoma (36.2%). Mean age of POAG patients was (54.2±7.2 years), PNAG was (60.1±11.1 years), NTG was of (64.6±11.8 years), ocular hypertension was of (55±7.2 years) and secondary glaucoma was of (53.2±11.2 years). PNAG was more common in females and rest of glaucoma was common in male. Glaucoma, Profile, Visual impairment, Eastern U.P. Conclusion: Glaucoma causes progressive atrophy of the optic disc resulting in typical defects in the visual field. It can lead to total loss of vision if left untreated. The diagnosis glaucoma has to be made only after comprehensive eye examination and not only on one parameter. Regular follow up is must to access progression which is essential for glaucoma. Glaucoma awareness has to be created among peoples, for them to get examined at early stage to rule out presence of glaucoma. If glaucoma is found, appropriate management is provided to prevent visual function impairment or loss. Keywords: Glaucoma, Profile, Visual impairment, Eastern UP
Parental Stress Experiences with NICU Admission in a Tertiary Care Centre

Objective: To determine the stress levels among parents of babies admitted in Neonatal Intensive Care Unit (NICU) and to identify demographic parameters that influence their stress levels. Methods: A cross sectional study was done at a tertiary care hospital in South India over a three month period. Stress levels were assessed using Parental Stressor Scale: Neonatal Intensive Care Unit (PSS: NICU) questionnaire among 100 extramural NICU parents (mother or father) by doctors with more than 24 hours of admission. Stress was quantified using Likert scale. The statistical analysis was done using R programming software. Results: The mean scores for the subscales sights and sounds, looks and behavior, alteration in the parental role and staff behavior and communication were (1.75), (2.11), (2.48) and (1.47) respectively. Maturity of baby, parents’ gender in sights and sounds domain and parents’ education in staff behavior domain were associated with higher stress levels respectively, as rest of the stress levels are not significant due to small sample size. Conclusions: Combined, the findings of the present study which not only documents stress experienced by parents of NICU infants but also highlight emotional consequences and the individual nature of parents’ response to the NICU experience. NICU parents are under moderate stress and appropriate counseling targeted towards specific stressors is required. Future research should monitor more closely how parental stress changes throughout the infant’s NICU stay. This information can be used to design effective coping strategies for parents at different time points during their infant’s hospitalization.
Bed bath for infarcted patients: crossover of the hydrothermal control 40ºC versus 42.5ºC

Aim: To compare the results of the water used to bath infarcted patients in bed under oxy-hemodynamic variables. Method: This research uses a 2X2 crossover of the interventions: bed bath with constant water temperature at 40°C (BB1) and 42.5°C (BB2) in 20 patients who had acute myocardial infarction (AMI). Dependent variables are: pulse oximetry, cardiac frequency (CF) and axillary temperature (Axt). The inferential statistics will be used in an analysis of the variations found repeated throughout the sample, as well as the Bonferroni test, with a level of significance of 5%. Results: The SpO2 and Axt were higher after BB2 (p<0.05) when compared with BB1. BB2 reduced CF by 1% (p=0.01). Discussion: The individual bath with controlled water temperature is capable of minimizing the oxy-hemodynamic impact. Conclusion: The bath with water temperature at 42.5oC was shown to be more favorable than at 40°C with regard to SpO2, CF and Axt in infarcted patients.
Radiofrequency-assisted minimally Invasive Manual Lumbar Discectomy using Disc-Fx System: Outcome of Nine Cases

Introduction: The preferred treatments for discogenic axial or radiating lower back pain are controversial. Available treatments are medication, physical therapy, epidural steroid, percutaneous endoscopic discectomy, open surgical discectomy, etc. A radiofrequency-assisted minimally invasive lumbar manual discectomy with nucleus ablation and annulus modulation by Elliquence’s “Disc-Fx system” has been successfully used to treat nine patients for their low back pain. Materials and methods: Nine patients (35–55 years/M:F = 2:7) with lower back pain radiating to leg that failed to improve with conservative managements for more than 6 weeks were assigned. The magnetic resonance imaging shows moderate size of single contained disc herniation at L4-5 or L5-S1 with minimal degenerative changes (preserved disc height). All Disc-Fx procedures were performed in a day care basis under fluoroscopic guidance under local anesthesia with or without minimal sedation. Evaluation with a global assessment scale at 6 weeks, 3and 6-months interval was done. Results: All the patients underwent Disc-Fx treatment at one level, either L4-5 or L5-S1, after confirming the diagnosis with preoperative provocative discography. Mean operation time was 60 to 90 minutes, mean postoperative recovery time was 60 to 90 minutes, and blood loss was minimal. Mean return to normal day-to-day activities was 7 days. The numerical rating scale score was significantly lower than before operation. No complication occurred except in one patient, who was not satisfied symptomatically (contacted on phone), but did not come for follow-up after procedure till date. Conclusion: Disc-Fx is an effective treatment option in discogenic pain and degenerative moderate contained disc prolapsed without bony and soft tissue stenosis. This minimally invasive approach does have advantages of no bony instability and minimal scarring/adhesion of epidural space, and thus, reduces postoperative complications to a great extent. It reduces hospital stay and leads to faster rehabilitation and early return to work, which reduces the cost of the treatment.
Review of “Global mean surface temperature and climate sensitivity of the EECO, PETM and latest Paleocene”

Abstract. Accurate estimates of past global mean surface temperature (GMST) help to contextualise future climate change and are required to estimate the sensitivity of the climate system to CO2 forcing during the geological record. GMST estimates from the latest Paleocene and early Eocene (~ 57 to 48 million years ago) span a wide range (~ 9 to 23 °C higher than pre-industrial) and prevent an accurate assessment of climate sensitivity during this extreme greenhouse climate interval. Here, we develop a multi-method experimental framework to calculate GMST during three target intervals: 1) the latest Paleocene (~ 57 Ma), 2) the Paleocene-Eocene Thermal Maximum (56 Ma) and 3) the early Eocene Climatic Optimum (EECO; 49.4 to 53.3 Ma). Using six independent methodologies, we find that average GMST estimates during the latest Paleocene and PETM are 11.7 °C (±0.6 °C) and 18.7 °C (±0.8 °C) higher than pre-industrial, respectively. GMST estimates from the EECO are 13.3 °C (±0.5 °C) warmer than pre-industrial and comparable to previous IPCC AR5 estimates (12.7 °C higher than pre-industrial). Leveraging the extremely large "signal" associated with these extreme warm climates, we combine estimates of GMST and CO2 from the latest Paleocene, PETM and EECO to calculate a gross estimate of the average climate sensitivity between the early Paleogene and today. This yields gross climate sensitivity estimates for the latest Paleocene, PETM and EECO which range between 2.8 to 4.8 °C (66 % confidence). These largely fall within the range predicted by the IPCC (1.5 to 4.5 °C per doubling CO2), but appear incompatible with low values (between 1.5 and 2.8 °C per doubling CO2).
Assessment of reproductive parameters of privately bred zebra finch (Taeniopygia guttata)

The aim of the study was to assess breeding of zebra finches kept in a flock in an amateur indoor aviary. The research was carried out at an amateur breeding facility in the Masovian Voivodeship in 2014–2018. The subject of the study was 5 pairs of zebra finches (Taeniopygia guttata) kept in an indoor aviary. Analysis of breeding was based on the following parameters: number of eggs laid, number of chicks hatched, and number of chicks reared from two broods each year. The reproductive parameters of the zebra finch pairs were varied. There were differences between individual pairs of birds for both the number of eggs laid per clutch and the number of chicks reared. Most of the zebra finch pairs had very good reproductive parameters; only a pair consisting of two albino individuals did not rear any offspring in any of the breeding seasons.
A Leader Doesn’t Sound Lesbian!: The Impact of Sexual Orientation Vocal Cues on Heterosexual Persons’ First Impression and Hiring Decision

In three studies (N = 340), we tested whether vocal cues to a person’s sexual orientation prompted sexual orientation discrimination in heterosexual individuals when hiring leaders. Our results inform how gender and sexual orientation intersect to produce discriminatory effects in the hiring context. Heterosexual participants listened to short clips of voices that sounded like job candidate was a lesbian or heterosexual woman, or a gay or heterosexual man, and rated all for job suitability and employability. Candidates applied for jobs as leaders (Study 1), as leaders or assistants (Study 2), and for leadership roles that varied in both gender role and status (Study 3). Sexual orientation discrimination occurred in all three studies and was greater among women job candidates. Refuting role congruity theory, several findings disconfirmed the prediction that lesbian-sounding women would be advantaged when stereotyped as masculine and when applying for leadership roles. Rather, in line with status-beliefs theory, lesbian-sounding women and gay-sounding men were rated and ranked poorly to the extent that they were perceived as less competent than heterosexual candidates. Findings suggest that hiring discrimination occurs in subtle ways, such as when individuals sound gay/lesbian. This has implications for recruitment as well as sexual-orientation discrimination court cases. Online slides for instructors who want to use this article for teaching are available on PWQ's website at http://journals.sagepub. com/doi/suppl/10.1177/0361684319891168
Prevalência de cistos ovarianos em vacas de alta produção submetidas a sistema de confinamento e dieta total

Objetivou-se avaliar prevalência de cistos ovarianos em vacas leiteiras de alta produção, no pós-parto, submetidas ao regime de dieta total em três sistemas diferentes: Compost Barn, Free Stall e confinamento a céu aberto no sudoeste do estado de Goiás. Foram avaliadas 1600 vacas, HPB, de sete rebanhos, das quais 792 (49,5%) estavam vazias e com atraso nos protocolos reprodutivos. Ao exame ultrassonográfico o escore ovariano foi classificado em: Grau 1 (61,4%), Grau 2 (18,1%), Grau 3 (4,0%) e Cistos Ovarianos (16,5%). Quanto ao sistema de produção as prevalências de cistos foram: 16% no Free Stall, 17,2% no Compost Barn e 16,2% no confinamento a céu aberto, diferenças somente numéricas, mas não significativas estatisticamente. 84,7% (n=131) dos animais estavam em anestro, na presença do diagnóstico cisto folicular. 67,7% desses animais, situavam-se entre 60 a 180 dias pós-parto. Divididos em 27,5% entre 60 e 90 dias, 24,5% entre 91 e 120 dias, 15,5% entre 121 e 150 dias e 32,5% entre 151 e 500. A prevalência dos cistos em função do número de lactações foi: 29,8% na primeira, 26,7% na segunda, 24,4% na terceira, 5,3% na quarta, 4,6% na quinta e 9,2% na sexta, resultados estatísticos significativos para maior ocorrência de cistos nas três primeiras lactações. Quanto ao escore de condição corporal 62,6% das vacas com cisto ovariano mostraram-se com escore entre 2,0 a 2,5, 25,2% entre 2,6 a 3,0 e 12,2% entre 3,1 a 4,0, resultados significativos, e a chance de vacas em balanço energético negativo desenvolverem cistos foi 5,1 vezes maior, quando comparadas com animais em escore corporal ideal. Os cistos foliculares apresentam-se com elevada casuística em vacas de alta produção leite, impactando em subfertilidade e prejuízos importantes na pecuária leiteira mundial, assim, faz-se necessário outros estudos visando o desenvolvimento de medidas preventivas mais eficazes no controle deste quadro.
Super quantum discord and other correlations for tripartite GHZ-type squeezed states

A comparison is made between normal discord, super quantum discord, and entanglement for the tripartite Greenberger-Horne-Zeilinger (GHZ)-type squeezed states. For this aim, we start by studying the behavior of quantum discord for tripartite GHZ-type squeezed states. Also, we verify the monotonicity of the super quantum discord according to weaker quantum measurements. This was done by manipulating the amount of quantum information lost during the disruption of our quantum system and by controlling the measurement strength. Furthermore, we calculate the entanglement for our system.
A Phase 1b Dose Escalation Safety Analysis of Lenalidomide and Azacitidine Maintenance Therapy for Poor Risk AML

Abstract 3625 Background: Despite achieving remission after intensive chemotherapy for AML, the majority of patients will relapse. Maintenance therapy is an attractive option, with the goal of eradicating residual disease and prolonging disease remission. The hypomethylating agent azacitidine and the immunomodulatory drug lenalidomide have been shown to be active in high risk MDS, especially in combination (Sekeres et al , Journal of Clinical Oncology 2010; 2253). Azacitidine maintenance therapy has been examined after intensive induction chemotherapy for high risk MDS and MDS progressing to AML (Grovdal et al , British Journ of Haem 2010; 293). In this study, an azacitidine dose of 75 mg/m 2 resulted in excessive neutropenic toxicity. An amended dose of azacitidine 60 mg/m 2 for 5 days each cycle was found to be deliverable, with acceptable hematopoietic toxicity. The goal of this study was to determine the optimal maintenance dosing schedule of azacitidine in combination with lenalidomide after intensive chemotherapy for AML in complete remission (CR) and a high risk of relapse. Methods: A phase Ib/II open label dose escalation study enrolled patients with high risk AML in CR/CRi and high risk features (age > 60, adverse risk karyotype, FLT3-ITD+ or CR2). Patients were treated with azacitidine subcutaneously on days 1–5 of each 28-day cycle combined with lenalidomide orally on days 5–25 for a maximum of 12 cycles. A 3×3 dose escalation schema to identify the maximum tolerated dose was conducted. Cohort A (Table 1) assessed the safety of azacitidine 50 mg/m 2 alone. Cohorts B-H planned to investigate azacitidine 50–75 mg/m 2 in combination with lenalidomide 5–25mg. Results: We report herein the analysis of the first 16 patients (M 8, F 8), median age 65 years (43–73) recruited to the study. Patients were at high-risk for relapse, based on age >60 years (n=11), CR2 (n=3), adverse risk karyotype (n=1) or FLT3-ITD+ (n=1). Neutrophil (Figure 1) and platelet (Figure 2) toxicity was modest during cycle 1. A summary of outcomes is shown in table 1. After a median follow-up of 301 days, 6/16 patients have relapsed with a median relapse-free survival (RFS) of 219 days (17–546) and median overall survival (OS) of 443 days (86–546). Dose-escalation is ongoing. Conclusion: The combination of azacitidine with lenalidomide as maintenance therapy after intensive chemotherapy for high-risk AML is well tolerated. The clinical efficacy of this regimen and the maximum tolerated dose remains to be determined. Disclosures: Wei: Celgene: Honoraria, Research Funding. Schwarer: Novartis: Honoraria, Membership on an entity9s Board of Directors or advisory committees; Bristol-Myers Squibb: Honoraria, Membership on an entity9s Board of Directors or advisory committees; Janssen-Cilag: Honoraria; Hospira: Membership on an entity9s Board of Directors or advisory committees. Harrison: Celgene: Honoraria, Membership on an entity9s Board of Directors or advisory committees, Research Funding. Tam: Celgene: Honoraria.
A side effect of a university boom: rising incidence of overeducation among tertiary educated workers in Poland

Abstract This paper analyses changes in overeducation incidence in Poland in 2006‑2014. It finds that a rise in number of tertiary educated workers outpaced an increase in number of jobs requiring tertiary education, which resulted in a substantial growth of overeducation incidence. The overeducation increase was driven mainly by mild overeducation rather than severe overeducation. Overeducated workers are usually young with little job experience. Women are found at lower risk of severe overeducation compared to men, but relatively more at risk of mild overeducation. A low risk of overeducation is associated with having studied technical and health programmes.
An Outcome and Process Evaluation of ‘Food Fit:’ A Theory Based Childhood Overweight Prevention Curriculum

A Social Cognitive Theory based (SCT) nutrition intervention (Food Fit – FF) was designed and implemented with 3-5 grade children to impact diet quality and specific food selection behaviors associated with the prevention of childhood overweight. During the intervention children participated in hands-on activities and role-playing, and were encouraged to taste healthy foods and beverages. Evaluations included per lesson pre and posttests to evaluate psychosocial variables, and a standardized instrument to evaluate dietary behaviors. Process evaluations were conducted to assure program integrity. Children were also given a choice between food items after each lesson and reported the main reason for their selection. Favorable outcomes were seen for dietary behaviors (i.e. raw vegetable consumption (p<0.0006)), and psychosocial variables (i.e. outcome expectancies for eating raw vegetables (p<0.009)). These results suggest that participation in the FF program can positively and significantly enhance psychosocial varialbes of SCT related to specific
Resultados clínicos de un programa de protección renal en pacientes con enfermedad renal crónica estadio 5 en Medellín, Colombia. Informe preliminar

Introduccion: La enfermedad renal cronica continua siendo una causa importante de morbilidad y mortalidad en nuestro medio. La adecuada intervencion medica de los factores de riesgo de la enfermedad retarda que vaya en progresion a dialisis. La utilidad de los programas de proteccion renal en nuestro pais no ha sido evaluada. Objetivo: Describir las caracteristicas clinicas y los resultados medicos obtenidos en los pacientes con enfermedad renal cronica estadio 5 pertenecientes a un programa de proteccion renal. Materiales y metodos: Un total de 4727 pacientes pertenecen al Programa de Proteccion Renal del Hospital General de Medellin-Savia Salud iniciado en noviembre de 2013 y con seguimiento hasta el 31 de diciembre de 2015. Se incluyeron aquellos pacientes con GFRe por Cockcroft-Gault 694) y la reduccion promedio en la GFRe por MDRD fue de -2,88 ml/min/ano. Conclusiones: Los programas de proteccion renal son una herramienta util en el manejo de pacientes con enfermedad renal cronica avanzada, puesto que retrasan una evolucion hacia la dialisis.
Students Perceptions about Celebrity Endorsement

The instrument of celebrity endorsement has nowadays become a pervasive element in advertising and communication management. It is unanimously accepted that celebrity endorsement can grant extraordinary characteristics to a product or service that may have lacked otherwise. The great number of celebrities endorsing brands has been increasing over the past decades. The purpose of this study is to examine perceptions of the student population in Bosnia and Herzegovina (hereafter named BiH) about the celebrity endorsement. Questionnaire is designed and used to survey a randomly selected sample of university students and 125 usable responses were obtained. During the research, five hypotheses have been tested. Data were analyzed by performing descriptive statistics and Chi-Square test. Chi-Square test was used to analyze relationship between nationality of respondents and factors that influence decision of choosing celebrity endorser by firm. Findings show that students perceive celebrities as a very important factor in advertisements.
Flow Diversion for Intracranial Aneurysms

advances have taken place in the endovascular management of intracranial aneurysms. Endoluminal devices such as stents were developed initially as adjuncts during coiling of complex lesions. However, after clinical experience and fl ow velocimetry studies, it was eventually recognized that stents could play a role in modifying local hemodynamics and treating aneurysms without the necessity of intrasaccular manipulation. The concept of flow diversion was then adopted to describe this novel treatment strategy, emphasizing the ability of these devices to divert blood fl ow away from the aneurysm into the parent artery, eventually leading to intra-aneurysmal thrombosis and obliteration (Figure 1). Flow diverters were refi ned to achieve the desired hemodynamic effect and initially were tested during in vitro and animal studies, with promising results. They were later introduced into clinical practice and now constitute an important therapeutic tool in the treatment of complex aneurysms. In this review, we summarize the development of fl ow diversion devices and the relevant evidence regarding their use in clinical practice, with special attention to effi cacy and safety data.