Miracle-dz/UniFAR-FTUs huggingface dataset:
In Silico Analysis of a MRP Transporter Gene Reveals Its Possible Role in Anthocyanins or Flavonoids Transport in Oryze sativa

There are many studies on enzymatic pathways of anthocyanin biosynthesis, but little is known about the anthocyanins transport in Oryze sativa. In silico analysis, the OsMRP15 (LOC_Os06g06440), an orthologous gene of mazie anthocyanin transporter ZmMRP3, has been identified in rice. The OsMRP15 contained a 4425bp open reading frame (ORF) encoding a 1475 amino acid protein, belonging to a MRP subfamily of ABC transporters, and has a high sequence identity, very similar protein structure, and the same arrangement of domains to ZmMRP3, but the genomic structure of OsMRP15 was significant difference with ZmMRP3. The prediction promoter of OsMRP15 has many presumed anthocyanin regulatory sites. The phylogenetic analysis of MRPs in rice, mazie and Arabidopsis showed that OsMRP15 and ZmMRP3 belonged to the same subbranch. The expression pattern indicated that OsMRP15 was co-expression with two anthocyanin transcription factors. These analysis results implied that as an ortholog of ZmMRP3, the function of OsMRP15 was possibly as a membrane-bound transporter required for vacuolar uptake of anthocyanins in rice.
Étude rétrospective concernant 73 patients traités par un anticoagulant oral direct admis consécutivement dans un service d’urgence

MOTS CLÉS Anticoagulant oral direct ; Hémorragie ; Urgence Résumé Introduction. — Les anticoagulants oraux directs sont une alternative récente aux antivitamines K, et peu de données sur les patients bénéficiant de ces nouveaux traitements existent. Ce travail a pour objectif d’identifier et de décrire le profil des patients traités par un anticoagulant oral direct, admis dans un service d’urgences. Méthode. — L’ensemble des patients, traités par un anticoagulant oral direct, admis aux urgences du CHU de Clermont-Ferrand du 1er janvier 2013 au 31 août 2013, a été inclus dans cette étude rétrospective et descriptive. Résultats. — Parmi les 73 patients inclus, 47,9 % étaient traités par dabigatran et 52,1 % par rivaroxaban. Soixante-deux patients avaient une indication pour une fibrillation auriculaire, avec un score de CHADS2 moyen de 2,6 [2,3—3]IC95 %. L’âge moyen était de 76,4 ans [73,7—79,1]IC95 %. Vingt-neuf patients (39,7 %) avaient au moins une association médicamenteuse connue pour
Occurrence of selected veterinary pharmaceuticals in water from a fish pond settlement in Ogun state, Nigeria

Pharmaceuticals are emerging contaminants that are increasingly entering the water system. These include veterinary drugs which are used for treating, mitigating or preventing illness or influencing specific body functions in animals. This research is aimed at using HPLC to detect the presence of veterinary drugs that were extracted in fish-pond-wastewater and river water from an aqua cultural environment in Ijebu-Ode (Ogun State-Nigeria) using Solid Phase Extraction Cartridges (C8 and C18). The three pharmaceuticals tested were Oxytetracycline, Tetracycline and Chloramphenicol. All the pharmaceuticals, except Tetracycline, were found in varying concentrations with the highest value for Chloramphenicol found to be 0.60ng/ml and that of Oxytetracycline was 0.46ng/ml. The discovery of Chloramphenicol and Oxytetracycline in water using SPE-HPLC is novel in Nigeria. This result showed the prevalence of pharmaceuticals in water in this small community which occasionally depends on river water for domestic purposes. Establishing modern wastewater treatment devices which can conveniently remove pharmaceuticals in water before they are discharge into the environment is recommended as this will help to preserve our ecosystem.
HYBRID FINITE-DIFFERENCE/MODE-MATCHING METHOD FOR ANALYSIS OF SCATTERING FROM ARBITRARY CONFIGURATION OF ROTATIONALLY- SYMMETRICAL POSTS

In this paper, the hybrid approach to the analysis of electromagnetic wave scattering from arbitrary conflguration of body- of-revolution (BOR) posts is presented. The proposed approach is based on the representation of each scatterer or set of scatterers by an efiective sphere with the known boundary conditions deflned by transmission matrix. In the analysis of each single axially- symmetrical post with irregular shape we utilize the flnite-difierence frequency-domain/mode-matching technique (FDFD/MM). Then the scattering parameters of investigated set of posts are obtained utilizing the analytical iterative scattering procedure (ISP). This work is an extension of our previously published results where the proposed technique was deflned in cylindrical coordinates and was limited to conflgurations of inflnitely long parallel cylinders with arbitrary cross- section. In this paper we extend this method by formulating it in spherical coordinates. This allows us to signiflcantly increase the versatility of the developed approach and in result to include in the analysis the sets of arbitrary located and oriented rotationally- symmetrical posts. The accuracy and e-ciency of the proposed technique are discussed. The presented numerical results are verifled with the ones obtained from commercial software.
Closing A Conceptual Gap: The Case For A Description Of English As A Lingua Franca

Despite momentous developments in the sociopolitics of the teaching of English worldwide, targets have generally remained tied to nativespeaker norms. This paper argues that although this orientation is often recognized as inappropriate and counter-productive, it persists because discussions about ‘global English’ on the meta-level have not been accompanied by a necessary reorientation in linguistic research: very little empirical work has so far been done on the most extensive contemporary use of English worldwide, namely English as a lingua franca, largely among ‘non-native’ speakers. The paper seeks to demonstrate that this lack of a descriptive reality precludes us from conceiving of speakers of lingua franca English as language users in their own right and thus makes it difficult to counteract the reproduction of native English dominance. To remedy this situation, a research agenda is proposed which accords lingua franca English a central place in description alongside English as a native language, and a new corpus project is described which constitutes a first step in this process. The paper concludes with a consideration of the potentially very significant impact that the availability of an alternative model for the teaching of English as a lingua franca would have for pedagogy and teacher education.
Physical properties of Brazil nuts

The Brazil-nut, also known as Para-nut, is widely used as food and in cosmetic industries. The seeds are rich in lipids and protein, and also present a considerable amount of selenium. Limited research has been conducted on postharvest of the Brazil nut, being an important information to design equipment related to aeration, drying, storage and transportation steps. Thus, the objective of this study was to determine the physical properties of the Brazil-nut with and without tegument. The dimensions found for the almonds with tegument were 39.35 mm in the X axis, 24.19 mm in the Y axis, and 17.88 mm in the Z axis. However for the almond without tegument the values were 31.05 mm in X, 14.38 in Y and 15.91 mm in Z axis. The sphericity was 66.40% and 51.59% for the kernels with and without seed tegument respectively. The kernels with and without tegument presented sphericity of 63.00% and 47.72% respectively. The mass of 1000 almonds was 6.13 kg for almond with teguments and 3.18 kg for almonds without teguments. Specific mass of 0.947 g.cm -3 and 1.003 g.cm -3 for the kernels with and without tegument, coupled with a porosity of 46.88% and 37.60% and, resulting on a bulk density of 0.504 g.cm -3 and 0.626 g.cm -3 for almonds with and without teguments respectively. Finally, the angle of repose for the kernels with teguments was 36.37°.
Nutrient-chlorophyll relationships : an evaluation of empirical nutrient-chlorophyll models using Florida and north-temperate lake data

Nutrient-chlorophyll (CHL) relationships were developed using a large data set collected in Florida over the last 10 years consisting of monthly total phosphorus (TP), total nitrogen (TN), and CHL concentrations from 360 lakes. The precision of these and five additional published relationships was examined. The 95% confidence interval for the best available TP-CHL model is 30-325% of the calculated CHL value. Analysis of associated Florida monthly nutri­ ent and CHL data indicate that the TP-CHL relationship is sigmoid, although a linear response is found for TP con­ centrations in the range of 3-160 J.lg. L- 1 . The maximum CHL responses for a sigmoid curve and straight line are similar for TP concentrations of 3-100 J.lg-L- 1 . Both relationships describe P limitation when the CHL response falls on or near the line and provide a benchmark to evaluate other limiting or colimiting factors that are indicated when the CHL response falls below the line. Florida and global data are similar, exhibiting a lessening of slope above a TP con­ centration of 100 J.lg·L-I. A global median line is derived from a large population of lake data for use in general lake management. Resume: Nous avons examine les relations entre les nutriants et la chlorophylle a partir d'une grande base de donnees recueillies en Floride depuis 10 ans, representant les concentrations moyennes de phosphore total (PT), d'azote total (NT) et de chlorophylle (CHL) dans 360 lacs. Nous avons examine la precision de ces relations et de cinq autres etu­ des publiees sur Ie sujet. L'intervalle de confiance de 95% pour Ie meilleur modele PT-CHL correspond a 30% a 325% de la valeur calcuIee de CHL. L' analyse des donnees mensuelles associees (pour la Floride) sur les nutriants et la CHL indique que la relation PT-CHL est sigmolde, tandis qu'on observe une reponse lineaire pour les concentrations de PT dans la fourchette de 3 a 160 J.lg·L- 1 . La reponse maximum de CHL pour la courbe sigmolde et la ligne droite sont similaires dans la plage de concentration de PT de 3-100 J.lg·L- 1 • Les deux relations revelent une limitation par Ie phosphore quand la reponse de CHL tombe sur la ligne ou a proximite, et fournissent un jalon perrnettant d'evaluer d'autres facteurs limitants ou colimitants qui sont signaIes par Ie fait que la reponse de CHL tombe au-dessous de la ligne. Les donnees obtenues en Floride et ailleurs dans Ie monde sont similaires, et montrent un abaissement de la courbe au-dessus d'une concentration de PT de 100 J.lg·L-I. Nous avons calcule une ligne mediane globale a partir d'un vaste corpus de donnees sur les lacs, ce qui peut servir a la gestion d'ensemble des lacs. (Traduit par la Redaction)
Short- and long-term effects of developmental corticosterone exposure on avian physiology, behavioral phenotype, cognition, and fitness: A review

A growing body of evidence from across taxa suggests that exposure to elevated levels of glucocorticoids during early development can have long-term effects upon physiological and behavioral phenotypes. Additionally, there is some, though limited, evidence that similar early exposure can also negatively impact cognitive ability. Following pioneering mammalian stud- ies, several avian studies have revealed that the responsiveness of the hypothalamo-pituitary-adrenal (HPA) axis as an adult can be explained by levels of corticosterone, the avian glucocorticoid, the individual experienced as a nestling or even as an embryo via yolk exposure. Studies also suggest that perinatal exposure to corticosterone can have effects upon avian 'personalities' or coping styles, and findings from mammalian studies suggest that these long-term effects are mediated epigenetically via altered expression of relevant DNA sequences. Although a consistent pattern across-species has yet to emerge, recent work in Florida scrub-jays Aphelocoma coerulescens found that baseline corticosterone levels in 11-day-old nestlings explained 84% of the varia- tion in 'personality' (bold vs. timid) when those individuals were tested approximately seven months later. Nestlings with ele- vated corticosterone levels were more timid than those individuals that as nestlings experienced relatively low corticosterone lev- els. Some researchers have suggested that parents might use such mechanisms to 'program' their offsprings' phenotype to best fit prevailing environmental conditions. This review will visit what is known about the links between stressful developmental condi- tions that result in exposure to elevated corticosterone and the short- and long-term effects of this steroid hormone upon central nervous system function and whether alterations thereof are beneficial, deleterious, or neutral. It will concentrate on examples from birds, although critical supporting studies from the mammalian literature will be included as appropriate (Current Zoology 57 (4): 514-530, 2011).
Late-replicating CNVs as a source of new genes

Asynchronous replication of the genome has been associated with different rates of point mutation and copy number variation (CNV) in human populations. Here, our aim was to investigate whether the bias in the generation of CNV that is associated with DNA replication timing might have conditioned the birth of new protein-coding genes during evolution. We show that genes that were duplicated during primate evolution are more commonly found among the human genes located in late-replicating CNV regions. We traced the relationship between replication timing and the evolutionary age of duplicated genes. Strikingly, we found that there is a significant enrichment of evolutionary younger duplicates in late-replicating regions of the human and mouse genome. Indeed, the presence of duplicates in late-replicating regions gradually decreases as the evolutionary time since duplication extends. Our results suggest that the accumulation of recent duplications in late-replicating CNV regions is an active process influencing genome evolution.
Learning from Experience? Second-Order Policy Devolution and Government Responsiveness

Proponents of devolution often claim that the decentralization of policymaking authority to sub-national governments generates better outcomes because decision-making takes place “closer to the people”. Yet, the theoretical rationale for why devolution might improve outcomes often remains unspecified. We unpack this argument by formally stating one causal relationship that is often left implicit-devolution leads to experimentation, learning by administrators, and better policy outcomes. We then offer an exploratory empirical examination of this argument. We utilize data collected after the decentralization of welfare-related policymaking authority to local leaders in one American state, North Carolina. We employ case studies, survey research, and budgetary data from 1998 to 2003. Our findings suggest that while some experimentation did occur as a result of devolution, local officials in North Carolina rarely replicated policy decisions that led to improved outcomes in their communities. We conclude that a key argument used to advance policy devolution across a number of countries and political regimes is in need of reevaluation and, potentially, revision.
Lymphangioleiomyomatosis: An unusual age of diagnosis with literature review

Lymphangioleiomyomatosis (LAM) is a rare idiopathic disorder of unclear origin, which almost exclusively occurs to women before menopause. It is characterized by nonneoplastic diffuse proliferation of atypical immature smooth muscle cells around small airways and vessels. We report the case of a 64-year-old woman kept for chronic progressive dyspnea related to a diffuse LAM. The discussion includes a literature review that describes the physiopathology, clinical features, chest computed tomography aspects, and differential diagnosis regarding this rare disease. Through this case report, pulmonary LAM should be included in the list of differential diagnoses for cases of pulmonary cystic lesions, even in postmenopausal women.
Transaction Update method based on Fuzzy Chunk for QoS Performance Improvement of Mobile Streaming Service

Abstract There exist many QoS problems such as delay and jitter for mobile streaming due to limited bandwidth. This paper proposed a transaction update method based on Fuzzy chunk to solve the problems. The proposed method updated a transaction, which is classified as a read or an update, using Fuzzy filtering. A chunk block is rearranged according to the fuzziness which is classified as better relevance for fuzziness greater than 0.8, relevance for fuzziness between 0.5 and 0.7, and less irrelevance for fuzziness less than 0.5. According to the simulation result for the rearranged chunk block, the proposed method has better performance than those of RBM(Randon Based method), DBM(Distance Based Method), and FBM(Frequency Based Method). Keywords : QoS, Transaction Update, Fuzzy Chunk, Relevance 1. 서론 최근에 무선통신 및 이동통신의 발달로 인하여 사용자가 이동하면서 데이터를 서비스 받기 위한 모바일 스트리밍 서비스에 대한 관심이 증가되고 있다. 모바일 스트리밍 서비스는 컴퓨터, 방송, 가전, 통신기술이 상호 컨버전스 되어 실시간 정보 서비스를 제공하는 형태로 빠르게 진 ※ 제일저자(First Author) : 정택원접수일:2008년 09월 26일, 완료일:2008년 12월 17일
Multi-satellite aerosol observations in the vicinity of clouds

Improved characterization of aerosol properties in the vicinity of clouds is important for better understanding two critical aspects of climate: aerosol–cloud interactions and the direct radiative effect of aerosols. Satellite measurements have provided important insights into aerosol properties near clouds, but also suggested that the observations can be affected by 3-D radiative processes and instrument blurring not considered in current data interpretation methods. This study examines systematic cloud-related changes in particle properties and radiation fields that influence satellite measurements of aerosols in the vicinity of low-level maritime clouds. For this, the paper presents a statistical analysis of a yearlong global dataset of co-located MODIS and CALIOP observations and theoretical simulations. The results reveal that CALIOP-observed aerosol particle size and optical thickness, and MODIS-observed solar reflectance increase systematically in a wide transition zone around clouds. It is estimated that near-cloud changes in particle populations – including both aerosols and undetected cloud particles – are responsible for roughly two thirds of the observed increase in 0.55 μm MODIS reflectance. The results also indicate that 3-D radiative processes significantly contribute to near-cloud reflectance enhancements, while instrument blurring contributes significantly only within 1 km from clouds and then quickly diminishes with distance from clouds.
Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog

ABSTRACT Values of serum tartrate-resistant acid phosphatase(TRAP) activity were obtained in adult dogs and its biological variability was assessed. Nine healthy skeletally mature Portuguese Podengo were used dogsfor the determination of TRAP, and bone total alkaline phosphataseserum activities, and also to study their relationship with serum minerals, namely calcium (Ca), phosphorous (P), and magnesium (Mg). The serum TRAP activity was 2.19±0.56IU/mL, with intra-individual variation of 18.3% and inter-individual variation of 25.6%. Significant correlations were observed between serum TRAP activity and Ca ( r =-0.3431; P<0.05), Ca and Mg (r=-0.787; P<0.01), and TRAP and Mg ( r =0.397; P<0.05). The results indicate that serum TRAP activity in dog could be of great value in research and in clinical practice, providing complementary non-invasive information on bone metabolism. Keywords: dog, bone metabolism, bone resorption, osteoclast RESUMO Determinaram-se os valores da atividade da fosfatase acida resistente ao tartarato (FART) e avaliou-se a sua variabilidade biologica. , foram utilizados noNeste estudo ve caes adultos e saudaveis de raca Podengo Portugues para a determinacoes das atividades s da FART, da fosfatase alcalina total, da isoenzima ossea da fosfatase alcalinae da concentracao dos minerais sericos calcio, fosforo e –magnesio. A atividade serica obtida da FART foi de 2,19±0,56 UI/mL, com uma variacao intra-individual de 18,3% e interindividual de 256%. F,oram observadas correlacoes significativas ao longo do tempo entre FART e calcio (r=-0,3431; P<0,05), entre FART e magnesio (r=03974; , P<0,05) e entre calcio e magnesio (r=-0,787; P<0,01). Os resultados indicam que este marcador de reabsorcao ossea pode ser de grande valor na pratica clinica e na investigacaoe , ainda, ser utilizado como um metodo auxiliar nao invasivo para avaliacao do metabolismo osseo.
Accounting For Canada¡¯S Economic Growth

A dynamic stochastic general equilibrium model is constructed and calibrated to the Canadian economy. Technology disturbances from the Canadian economy are filtered through the model and used to generate artificial time series. Output growth in the model is then decomposed into the share weighted growth rates of the factor inputs and productivity. The model is then used to identify the endogenous responses of the factor inputs to the technology disturbances. The results suggest that much of the slowdown observed in Canadian output growth since 1974 can be explained by fluctuations in the rates of investment-specific and residual-neutral technological change.
Modeling Transaction Data of Trade Direction and Estimation of Probability of Informed Trading

This paper implements the Asymmetric Autoregressive Conditional Duration (AACD) model of Bauwens and Giot (2003) to analyze irregularly spaced transaction data of trade direction, namely buy versus sell orders. We examine the influence of lagged transaction duration, lagged volume and lagged trade direction on transaction duration and direction. Our results are applied to estimate the probability of informed trading (PIN) based on the Easley, Hvidkjaer and O’Hara (2002) framework. Unlike the Easley- Hvidkjaer-O’Hara model, which uses the daily aggregate number of buy and sell orders, the AACD model makes full use of transaction data and allows for interactions between buy and sell orders.
UvA-DARE ( Digital Academic Repository ) Restrictions of frequent frames as cues to categories : the case of Dutch Erkelens

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Pathfinding for the navigation of visually impaired people

A navigation system using an Android mobile device for the visually impaired is explored in this paper. This paper focuses on pathfinding algorithms and their implementations on Java platform. The boundary iterative-deepening depth-first search (BIDDFS) pathfinding algorithm is extended for bidirectional searching. Fast pathfinding is applied for the BIDDFS by reducing memory read and writes cycles, proposing the optimised BIDDFS. Fast pathfinding is also extended for the bidirectional BIDDFS, proposing the fast bidirectional BIDDFS. The fast bidirectional BIDDFS uses Java’s thread feature to implement a parallel structure. The optimised BIDDFS was able to record drastic improvements in pathfinding speeds compared to the standard BIDDFS. Likewise, the fast bidirectional BIDDFS recorded significant speed improvements over the parallel bidirectional BIDDFS.