Miracle-dz/UniFAR-FTUs huggingface dataset:
Feasibility Study of the Usage of Blockchain Technology in Online Privacy Protection

In the modern day, a lot of private information people want to protect can easily find its way onto the internet. Blockchain Technology is a computer design architecture created to keep information secure and immutable. To find a way to better protect private information, this study explored the feasibility of using a blockchain system to protect online privacy. This study focuses on regulating access to browser cookies by online web-servers. Before a webserver can access a cookie, a blockchain network will authenticate the web-server’s permissions. Request Latency, Transaction Latency, and Transaction Throughput scale with blockchain members used to determine this set-up’s feasibility. Due to continued technical difficulties related to the structure of the coding and available resources, the study could not be completed.
Anti-melanogenic activity of different extracts from aerial parts of Nepeta glomeruloasin on murine melanoma B16F10 cells

Nepeta glomerulosa Boiss. is a medicinal plant has been used in traditional medicine. The aim of this study was to evaluate the anti-melanogenesis inhibitory activity of MeOH, n-hexane, ethyl Acetate (EtAc), dichloromethane (CH2Cl2), n-butanol (BuOH) and H2O extracts isolated from N. glomerulosa in B16 melanoma cell line. The B16F10 cell line viability after treatment with increasing concentrations of different extracts of the plant (50-200 µg/ml) was measured by using MTT, the inhibitory effect on synthesis of melanin, mushroom tyrosinase activity, cellular tyrosinase and effect on oxidative stress was determined by the colorimetric and fluorometric method. The data showed that at concentrations our results showed the melanogenesis inhibitory and antioxidant effects of N. glomerulosa on B16F10 cells may recommend a novel agent in diminishing skin pigmentation and skin aging in cosmetic industry.
Problems of supply process reliability assessment at small and medium-sized enterprises

In the paper, the basic objectives of supply process are discussed. The importance of reliability assessment for the supply and procurement process is mentioned and some basic factors are described. The example of supply process analysis for SME is shown. The most important faults/errors of the process are described. The low costs of the faults/errors counteractions are underlined.
Bioactivity-Guided Fractionation and NMR-Based Identification of the Immunomodulatory Isoflavone from the Roots of Uraria crinita (L.) Desv. ex DC

Uraria crinita is used as a functional food ingredient. Little is known about the association between its immunomodulatory activity and its metabolites. We applied a precise strategy for screening metabolites using immunomodulatory fractions from a U. crinata root methanolic extract (UCME) in combination with bioactivity-guided fractionation and NMR-based identification. The fractions from UCME were evaluated in terms of their inhibitory activity against the production of pro-inflammatory cytokines (IL-6 and TNF-α) by lipopolysaccharide (LPS)-stimulated mouse bone marrow-derived dendritic cells (BMDC). The role of the isoflavone genistein was indicated by the 1H NMR profiling of immunomodulatory subfractions (D-4 and D-5) and supported by the result that genistein-knockout subfractions (D-4 w/o and D-5 w/o) had a lower inhibitory activity compared to genistein-containing subfractions. This study suggests that genistein contributes to the immunomodulatory activity of UCME and will help in the standardization of functional food.
Help-Seeking Experiences of Hepatitis B Patients in Transnational Medical Care: The Solution to Health Inequality Is Social Mobility

This paper tracked hepatitis B patients from Medan, Indonesia to Penang, Malaysia under transnational medical care and has an understanding of their medical history and socioeconomic status. The condition of these patients improved as a result of good compliance with medical treatment, including lifestyle adjustment and regular medication. Under the influence of the marketization of healthcare, transnational medical patients in the social structure, based on their economic ability and socioeconomic status, may be expected to experience health inequalities. People with unhealthy medical distribution and weak socioeconomic status are easily prone to diseases due to environmental and social conditions; it is easier for such patients to delay or give up their medical treatment. After continuous tracking and increasing patient exposure to medical knowledge and self-care management opportunities, increasing awareness, screening, care, and treatment, the transmission of hepatitis B can be reduced to enable them to gain upward mobility by their capacities and thus improve their health. Social mobility is deemed the main approach to reduce social inequality. There have been limited medical clinical observations and tracking confirming this theory. This paper, which uses medical observation, confirmed that social mobility is considered as the principal key to reducing inequalities in health.
Generic Access Network Emulation for NGN Testbeds [ Invited Paper ]

Evaluating the user satisfaction with Next Generation Network applications requires, amongst others, to carefully study the impact of various access networks with differing performance characteristics. This paper presents the concept and implementation of a network emulator for IP-based packetswitched wired and wireless access technologies based on measurement results obtained in real access networks. We present a generic modeling process which consists of three stages: (1) metric and measurement methodology selection, (2) measurements in real access networks, and (3) access network emulation based on the measurement results. Whereas the proposed modeling concept is generic and can be applied to any metric, the implementation part of this paper focuses on changes to the Open Source Linux WAN emulator NetEm which are required to accurately emulate one-way delay for access networks. We propose two distinct emulation options and compare one-way delay measurement results for real access technologies against the emulated ones, emphasizing limitations and pitfalls related to access network emulation in general.
A rare case of tuberculosis verrucosa cutis on the buttocks

Dear Editor, Mycobacterium tuberculosis infection remains a serious health concern in Taiwan. It most commonly affects the lungs, but any organ can be involved. Cutaneous tuberculosis (TB) is a relatively rare manifestation of TB infection, consisting only 1% to 2% of all extrapulmonary TB cases. We herein report a case of tuberculosis verrucosa cutis presenting on the buttocks. A 51-year-old Taiwanese masonry worker with alcoholic liver cirrhosis and hepatocellular carcinoma presented to our dermatology outpatient department due to an enlarging verrucous plaque over the buttocks noted for 2 years (Figure 1A). The lesion started as a scaly plaque over the buttocks and the patient received treatment at a local clinic under the diagnosis of tinea corporis. However, the lesion gradually enlarged and became verrucous. Painful ulceration with serous discharge was also presented (Figure 1B). There were no obvious signs of infection. His laboratory data were within normal limits and chest radiography showed no obvious abnormalities. Skin biopsy was done at the border of the lesion. Histopathological examination showed pseudoepitheliomatous hyperplasia with dermal granulomatous inflammation composed of epithelioid histiocytes and mixed inflammatory cells (Figure 1C). Numerous Langerhans giant cells were identified in the granulomas (Figure 1C). Although Periodic Acid-Schiff staining, Grocott methenamine-silver staining, and Ziehl–Neelsen staining failed to identify any microorganism or acid-fast bacilli (AFB), tissue culture and polymerase chain reaction (PCR) both showed positive results for M. tuberculosis. Considering the clinical presentation and tissue culture results, a diagnosis of tuberculosis verrucosa cutis was made. Much improvement of the lesion was noted after treatment with rifampicin, isoniazid, ethambutol, and clarithromycin. Cutaneous TB is a relatively uncommon form of TB infection and remains a diagnostic challenge due to its diverse clinical manifestation, which depends on the immune status of the host and previous sensitization to the pathogen. Tuberculosis verrucosa cutis is a paucibacillary subtype of cutaneous TB caused by exogenous inoculation of M. tuberculosis or Bacillus Calmette-Guérin in previously sensitized individuals with moderate to high immunity. Clinically, tuberculosis verrucosa cutis commonly occurs at sites prone to trauma such as the distal extremities and the buttocks. It usually presents as a hyperkeratotic verrucous plaque with irregular boarders but can mimic various other cutaneous condition such as verruca vulgaris, verrucous carcinoma, cutaneous mycetoma, hyperkeratotic lupus vulgaris, hypertrophic lichen planus, or tertiary syphilis, leading to delayed diagnosis. Owing to its paucibacillary nature, AFB are rarely identified by tissue Ziehl-Neelsen staining, making it difficult to diagnose without tissue culture or PCR. The treatment of cutaneous TB is generally similar to that of pulmonary TB and surgical intervention may be beneficial in cases with localized infection.
Running Head : Geoduck embryogenesis and fertilization 1 2 Practical fertilization procedure and embryonic development of the New Zealand 3 geoduck clam ( Panopea zelandica ) 4 5

23 Despite the fact that a successful aquaculture industry for the geoduck Panopea 24 zelandica (Quoy & Gaimard, 1835) must rely on hatchery spat production, little is known 25 about the embryonic development of the species, which appears to be critical for larval 26 rearing success. The present study investigated the development of P. zelandica 27 embryos at 15°C and 35 ppt and the optimal sperm:egg ratios for fertilization under 28 hatchery conditions. P. zelandica broodstock were induced to spawn by serotonin 29 injection. Sperm and eggs were collected within 30 min post-release, and then stored 30 at 4°C for up to 4 h and 1.5 h, respectively. Fertilization was conducted at sperm:egg 31 ratios of: 50:1, 100:1, 500:1, 1000:1, and 10,000:1 with a sperm-egg contact time of 40 32 min. The optimal sperm:egg ratio was determined to be < 500:1 and the normal embryo 33 yield at 3 and 18 h post-fertilization (hpf) ranged from 83-96%. Since there was only 34 one female spawned, the sperm:egg ratio results cannot be generalized to the 35 population, but can be considered to be useful information for future studies. P. 36 zelandica eggs (~ 80 μm diameter) developed the first and second polar bodies within 37 15 20 and 50 55 min post-fertilization, respectively. The blastula appeared at ~ 8 hpf, 38 including the XR and XL cells and the presumptive shell field depression. Gastrulation 39 occurred at 12 18 hpf with organic material shell apparent at the shell field depression. 40 The mid-stage trochophore, which appeared at around 35 hpf had an apical plate with 41 an apical tuft. The shell field spread to form the periostracum, which expanded and 42 folded into right and left segments covering the late trochophore. The early D-stage 43 veliger appeared at 45 hpf with the soft body being enclosed by two valves and the 44 appearance of the velum. These observations will serve as the basis for future 45 analyses of P. zelandica embryogenesis and for optimization of commercial production 46 of D-veliger larvae. 47
Preparation and Evaluation of Carbamazepine Solid Lipid Nanoparticle for Alleviating Seizure Activity in Pentylenetetrazole-Kindled Mice

Objectives: The study aimed to prepare carbamazepine in solid lipid nanoparticle form (CBZ-SLN) in order to enhance its anticonvulsant effect. Method: Eight formulations of CBZ-SLNs were prepared by homogenization and ultra-sonication techniques. Results: The prepared CBZ-SLN showed a high entrapment efficiency% (39.66 ± 2.42%–71.91 ± 1.21%), a small particle size (45.11 ± 6.72–760.7 ± 5.25 nm), and a negative zeta potential (from −21.5 ± 1.02 to −38.4 ± 1.32 mv). The in vitro release study showed the slow release of CBZ from SLNs compared to CBZ aqueous dispersion (p < 0.05). The infrared spectroscopy and the thermal analysis revealed the compatibility of the drug with other ingredients and the presence of drug in the more soluble amorphous estate, respectively. The in vivo study on mice revealed that the CBZ-SLN had a higher anticonvulsant efficacy than CBZ aqueous dispersion after a lethal and chronic dose of pentylenetetrazole (PTZ) (p < 0.05). The histopathological examination of the hippocampus revealed a decrease in the percentage of degeneration in mice treated with the CBZ-SLN compared to the PTZ and CBZ groups. Conclusion: CBZ can be formulated as SLN with higher anticonvulsant activity than free CBZ aqueous dispersion.
CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF HEDYCHIUM MALAYANUM ESSENTIAL OILS (Komposisi Kimia dan Aktiviti Anti-agen-pengoksidaan Minyak Pati Hedychium malayanum)

The leaves and stems of Hedychium malayanum were hydrodistilled using a Clevenger-type apparatus to give 0.038 and 0.009% oils, respectively. Sixteen and seven compounds which made up 98.4 and 100% of the respective oils were identified using capillary GC and GC-MS with a DB-5 column. These oils contained high amount of monoterpene hydrocarbons with β-pinene being the main compound found in the leaves (39.1%) and the stems (46.7%) followed by α-pinene (22.3%) and β-caryophyllene (13.7%) which was found in the leaf oil and 1,8-cineole (17.7%) and α-pinene (16.9%) in the stem oil. Antioxidant test by 1,1diphenyl-2-picrylhydrazyl (DPPH) showed that the leaf oil was a stronger antioxidant (31.1%) than Trolox (28.4%), whereas the stem oil was the weakest antioxidant (23.9%). β-Carotene bleaching (BCB) in linoleic acid showed that both oils were weaker antioxidants than butylated hydroxytoulene (96.8% inhibition). However, the stem oil (79.8%) showed a good inhibition whereas the leaf oil possessed a moderate capacity (54.7%) to prevent the oxidation by linoleic acid.
Dairy wastewatertreatment using anaerobic filters

Viraraghavan, T. and Kikkeri, S.R. Dairy wastewater treatment using anaerobic filters. Can. Agric. Eng. 33: 143-149.A laboratory investigation was carried out to evaluate and compare the perfor mances of three plastic medium upflow anaerobic filters operating at 12.5±1°C, 21±1°Cand30±1°C, treatingdairy wastewater. Two of the reactors were started at 21±1°C and the third at 30±1°C.Steady-state operationof the three reactors was carried out at three different tem peratures, 12.5±1°C, 21±1°C and30±1°C respectively. Each reactor was operated sequentially at different HRTs (6d, 4d, 3d, 2d and Id). The difference in start-up performance (COD removal) between anaer obicfilters operating at21±1°C and30±1°C wasnotsubstantial. Atan HRT of 4 days, COD removals in the three anaerobic filters were approximately 92%, 85% and 78% at30±1°C, 21±1°C and 12.5±1°C respectively. Une recherche en laboratoire a permis d'evaluer et de comparer les rendements de trois filtres anaerobies en plastique a circulation ascendante, fonctionnant a 12,5 ±1 °C, 21 ±1 °C et 30 ±1 °C, et traitant les eaux usees d'une laiterie. Deux des reacteurs ont demarre a 21 ±1 °C et le troisieme a 30 ±1 °C. Les reacteursfonctionnerent en regime permanent a trois temperatures differentes, 12,5 ±1°C,21±1°Cet30 ±1 °C, respectivement. Chaque reacteur fonctionnait de maniere sequentielle a differents TRH (6j, 4j, 3j, 2j et lj). En ce qui a trait au rendement/demarrage (reduction de DCO), la difference n'etait pas importante entre les filtres anaerobies fonctionnant a 21±1°Cet 30 1°C.PourunTRHde 4jours, la reductionde DCOdans les troisfiltres anaerobies etait d'environ 92 %, 85 % et 78 %, a 30 ±1 °C, 21 ±1 °C et 12,5±1 °C, respectivement.
Drop Size and Drop Size Distribution Measurements by Image Analysis

One important issue in drop sizing by image analysis is the determination of the contour of the drops. The grey level corresponding to this contour strongly depends on the degree of focusing of a drop. This grey level is determined from an imaging model based on Fourier optics formalism. The presented method allows estimating the correct contour of a focused or of an out-of-focus droplet, for a large range of sizes. A size-independent criterion for the selection of drops accordingly to their position relative to the focus plane is also presented. This criterion is based on the estimation of the PSF width. The criterion is used to select drops within a controlled range of out-of-focus positions, which is necessary for the determination of drop size distributions in spray applications. The method is applied to calibrated objects to control the method accuracy. Sources of sizing errors are evaluated and techniques to enhance the sizing procedure and to deal with overlapped images are presented.
The Occurrence, Drivers, and Implications of Submesoscale Eddies on the Martha’s Vineyard Inner Shelf

AbstractThe occurrence, drivers, and implications of small-scale O(2–5) km diameter coherent vortices, referred to as submesoscale eddies, over the inner shelf south of Martha’s Vineyard, Massachusetts, are examined using high-frequency (HF), radar-based, high-resolution (400 m) observations of surface currents. Within the 300 km2 study area, eddies occurred at rates of 1 and 4 day−1 in winter and summer, respectively. Most were less than 5 h in duration, smaller than 4 km in diameter, and rotated less than once over their lifespan; 60% of the eddies formed along the eastern edge of study area, adjacent to Wasque Shoal, and moved westward into the interior, often with relative vorticity greater than f. Eddy generation was linked to vortex stretching on the ebb and flood tide as well as the interaction of the spatially variable tide and the wind-driven currents; however, these features had complex patterns of surface divergence and stretching. Eddies located away from Wasque Shoal were related to the movem.
Phylotranscriptomic Analyses Reveal Asymmetrical Gene Duplication Dynamics and Signatures of Ancient Polyploidy in Mints

Abstract Ancient duplication events and retained gene duplicates have contributed to the evolution of many novel plant traits and, consequently, to the diversity and complexity within and across plant lineages. Although mounting evidence highlights the importance of whole-genome duplication (WGD; polyploidy) and its key role as an evolutionary driver, gene duplication dynamics and mechanisms, both of which are fundamental to our understanding of evolutionary process and patterns of plant diversity, remain poorly characterized in many clades. We use newly available transcriptomic data and a robust phylogeny to investigate the prevalence, occurrence, and timing of gene duplications in Lamiaceae (mints), a species-rich and chemically diverse clade with many ecologically, economically, and culturally important species. We also infer putative WGDs—an extreme mechanism of gene duplication—using large-scale data sets from synonymous divergence (KS), phylotranscriptomic, and divergence time analyses. We find evidence for widespread but asymmetrical levels of gene duplication and ancient polyploidy in Lamiaceae that correlate with species richness, including pronounced levels of gene duplication and putative ancient WGDs (7–18 events) within the large subclade Nepetoideae and up to 10 additional WGD events in other subclades. Our results help disentangle WGD-derived gene duplicates from those produced by other mechanisms and illustrate the nonuniformity of duplication dynamics in mints, setting the stage for future investigations that explore their impacts on trait diversity and species diversification. Our results also provide a practical context for evaluating the benefits and limitations of transcriptome-based approaches to inferring WGD, and we offer recommendations for researchers interested in investigating ancient WGDs in other plant groups.
An outbreak of ST307 extended-spectrum beta-lactamase (ESBL)–producing Klebsiella pneumoniae in a rehabilitation center: An unusual source and route of transmission

Abstract Objective: Nosocomial outbreaks due to multidrug-resistant microorganisms in rehabilitation centers have rarely been reported. We report an outbreak of extended-spectrum beta-lactamase (ESBL)–producing Klebsiella pneumoniae (ESBL-K. pneumoniae) on a single ward in a rehabilitation center in Rotterdam, The Netherlands. Design: Outbreak description. Setting: A 40-bed ward of a rehabilitation center in the Netherlands. Methods: In October 2016, 2 patients were found to be colonized by genetically indistinguishable ESBL-K. pneumoniae isolates. Therefore, an outbreak management team was installed, by whom a contact tracing plan was made. In addition to general outbreak measures, specific measures were formulated to allow continuation of the rehabilitation process. Also, environmental cultures were taken. Multiple-locus variable-number tandem-repeat analysis and amplification fragment-length polymorphism were used to determine strain relatedness. Selected isolates were subjected to whole-genome multilocus sequence typing. Results: The outbreak lasted 8 weeks. In total, 14 patients were colonized with an ESBL-K. pneumoniae, of whom 11 patients had an isolate belonging to sequence type 307. Overall, 163 environmental cultures were taken. Several sites of a household washing machine were repeatedly found to be contaminated with the outbreak strain. This machine was used to wash lifting slings and patient clothing contaminated with feces. The outbreak was contained after taking the machine temporarily out of service and implementing a reinforced and adapted protocol on the use of this machine. Conclusion: We conclude that in this outbreak, the route of transmission of the outbreak strain via the household washing machine played a major role.
MUHAMMAD HUSHAM YOUSAF ANALYSIS OF SIMULATOR FEASIBILITY IN DEVELOPMENT OF WIRELESS SENSOR NETWORK APPLICATIONS

MUHAMMAD HUSHAM YOUSAF: Analysis of simulator feasibility in development of wireless sensor network applications Tampere University of technology Master of Science Thesis, 52 pages June 2017 Masters Degree Programme in Information Technology Major: Communication Systems and Networks Examiners: Professor Jarmo Harju and Postdoctoral Researcher Teemu Laukkarinen
Code Smells and Micro Patterns Dependencies

To better support software maintenance and evolution, it is important to evaluate the quality of a system, identifying defects, code smells and anti patterns as hints pointing to subsystems that require improvement. In this paper we analyze the possible dependencies existing among code smells and between code smells and micro patterns – structural characteristics capturing common programming techniques. Knowledge of possible relations could improve the detection techniques of code smells and provide hints on how to improve the quality of a system. We discover these relations in an experiment employing machine learning techniques.
Near-infrared Fe II emission in IZw 1 and other NLS 1 galaxies

We study the near-infrared (NIR) emission of IZw1 aimed at co nfirming the role played by Ly α fluorescence in the production of the Fe II spectrum. We also derive the first semi-empirical NIR FeII template from IZw1 that best represents that emission, allo wing its clean subtraction in other sources. A good overall match between the observed Fe II+Mg II features with those predicted by the best-fitted model was obtained. This semi-empirical tem plate is then fitted to the spectrum of Ark 564 and other Seyfert galaxies, showing that it nicely re produces the observed iron emission. Our work extends the current set of available Fe II t mplates into the NIR region.