Miracle-dz/UniFAR-FTUs huggingface dataset:
Stress-Induced Alteration in Chloride Transporters in the Trigeminal Nerve May Explain the Comorbidity between Depression and Migraine

Migraine is frequently comorbid with depression and anxiety disorders. In the case of depression and panic disorder, the associations seem to be bidirectional. Stress (activation of the hypothalamic-pituitary-adrenal axis) is thought to be involved in increasing the attack frequency. In the current review, it is argued that elevated levels of cortisol increase the function of chloride-ion transporter NKCC1 and decrease the function of chloride-extruder KCC2 in the trigeminal nerve. This leads to a diminished inhibitory effect of gamma-aminobutyric acid (GABA) and an enhanced likelihood of a migraine attack. Since migraine attacks themselves are stressful, and since brain areas are activated that could contribute to panic, anxiety and depression, a number of self-sustaining circular processes could occur that would explain the bi-directionality of the associations. On the basis of this hypothesis, several novel therapeutic approaches to counter the pathological process can be proposed. These include inhibition of corticotrophin releasing factor by CRF1 receptor antagonists, blockade of adrenocorticotropic hormone (ACTH) at the MC2 receptor, and inhibition of the hyperactive NKCC1 chloride-transporter.
Piezoelectric‐based hoop‐type interface for impedance monitoring of local strand breakage in prestressed multi‐strand anchorage

In this study, a piezoelectric‐based interface technique for impedance measurement is presented to monitor local strand breakage in multi‐strand anchorage systems. Firstly, a hoop interface‐based impedance measurement model is designed based on stress behaviors of the multi‐strand anchorage. Coupled dynamic behaviors between the lead zirconate titanate (PZT) interface and the target tendon anchorage are interpreted to determine sensitive frequency ranges under local strand breakage. Next, a prototype of the PZT interface is designed to fit into the target multi‐strand anchorage to monitor the stress variations induced by local strand breakages. Dynamic characteristics of the PZT interface are numerically analyzed to sensitively catch impedance signals in predetermined frequency ranges. Finally, a series of damage scenarios are tested on a full‐scale multi‐strand anchorage system to evaluate the feasibility of the PZT interface for monitoring a series of strand‐breakage cases. Impedance responses of the PZT interface prototype are analyzed to determine damage‐sensitive frequency ranges. Linear tomography of root‐mean‐square‐deviation (RMSD) indices is utilized to localize damaged strands.
Study of lipid profile in diabetic and non-diabetic chronic kidney disease patients on haemodialysis: a prospective comparative study from a sub Himalayan region in North India

Background: Diabetes mellitus (DM) is a major cause of chronic kidney disease (CKD) leading to diabetic kidney disease (DKD). Several studies have observed lipid profile abnormalities in non-diabetic CKD patients with and without haemodialysis. Our study aims to reveal lipid profile abnormalities both in DKD and non-diabetic CKD patients on haemodialysis. Methods: A prospective comparative study included 50 DKD and 50 non-diabetic CKD patients on haemodialysis and 50 controls after fulfilling the inclusion and exclusion criteria. The demographic and biochemical, including lipid profile parameters data of all subjects was collected and statistically analysed. p<0.05 was considered as statically significant. Results: A total of 100 study patients, 50 DKD and 50 non-diabetic CKD patients, both on haemodialysis revealed significant dyslipidaemia when compared to controls. Total cholesterol in DKD patients on haemodialysis when compared to controls (177.5±80.5 versus 146.5±31.8 mg/dl) was significantly elevated (p=0.01). Low density lipoprotein (LDL) in DKD patients when compared to controls (94.1±43.3 versus 76.3±26.3 mg/dl) was also significantly elevated (p=0.01). Triglyceride levels in both DKD and non-diabetic CKD patients on haemodialysis in comparison to controls (213.8±182.1 and 169.2±132.3 versus 109.2±28.9 mg/dl respectively) were significantly elevated (p=0.0002 and p=0.003 respectively). Similarly, very low-density lipoprotein (VLDL) levels in both DKD and non-diabetic CKD patients were also significantly elevated when compared to controls (p=0.002 and p=0.003 respectively) whereas high density lipoprotein (HDL) was significantly reduced. Conclusion: Both DKD and non-diabetic CKD patients on haemodialysis revealed significant dyslipidaemia, a major cause of increased risk for cardiovascular diseases necessitating early treatment with statins.
Integrating Diffusion of Innovations and Theory of Planned Behavior to Predict Intention to Adopt Electric Vehicles

Electric vehicles (EVs) are recognized as effective solutions to the global air pollution problem, attracting much attention from businesses, governments, and consumers. Despite the heightened interest, EV penetration rates remain low. This study thus focuses on consumers’ evaluation of EV innovation to provide implications for promoting EV adoption by proposing a theoretical model that integrates the diffusion of innovations theory and the theory of planned behavior to examine the relationship between consumers’ perceived innovation characteristics and the adoption of EVs; the study findings indicate that the evaluation of consumers’ EV innovation has a significant impact on consumers’ attitudes toward and intention for EV adoption. Several important innovation characteristics promote practical implications for spreading EV acceptance.
Rice milling quality as affected by drying method and harvesting time during ripening in wet and dry seasons

ABSTRACT Head rice recovery is known to decrease with the delay in harvesting during ripening, but this effect may differ between wet season (WS) and dry season (DS) and among different paddy drying methods. In five experiments, rice was harvested by hand between 25 and 45 days after flowering in DS and WS when temperature around harvest was slightly above and below 30°C, respectively. The highest head rice recovery was generally obtained when rice was harvested at 25 days after 75% flowering. Delaying harvest to 30 days resulted in significant reduction in head rice recovery in 3 out of 7 cases and further delay to 35 days resulted in significant reduction in 8 out of 10 cases. For the crops harvested 25 days after flowering and dried with a flatbed dryer head rice recovery improved compared to sun drying in two experiments. When harvesting was delayed, sun drying tended to reduce head rice recovery compared to artificial drying. Sun drying only in the morning also improved head rice recovery compared to drying for the whole day. For a given drying method, head rice recovery decreased with increase in heat sum from flowering to harvest. It is concluded that rice crops should be harvested in both DS and WS around 25 days after 75% flowering when heat sum with base temperature of 10°C was around 450–500 degree-days. If an artificial dryer is not available, rough rice should be sun dried only in the morning with frequent stirring and mixing to promote more even drying. Abbreviations: WS: wet season; DS: dry season
Um estudo empírico sobre reações emocionais de usuários na interação com interfaces web pautadas na Gestalt

Resumo. Emoções influenciam decisões, comunicação com outras pessoas e com soluções web. As interfaces de usuário têm influência emocional sobre seu usuário e uma teoria para o design delas é a da Gestalt. Ainda é desconhecido sua influencia sobre as emoções durante uma interação. Este artigo realizou uma coleta de dados fisiológicos de voluntários durante o uso da solução web desenvolvida. Depois, classificou-se os dados de acordo com o Espaço Semântico de Scherer. Avaliou-se o impacto das leis sobre as emoções dos participantes. Os resultados sugeriram que as leis escolhidas mudaram de forma significativa uma pequena parcela dos voluntários.
KHV, CNGV or CyHV-3, which is the koi/carp killer?

Carp interstitial nephritis and gill necrosis virus (CNGV) is the cause of a lethal disease that afflicts koi and carps. Four genes of this virus are similar to those of Cyprinid herpesvirus 1 (CyHV-1) and Cyprinid herpesvirus 2 (CyHV-2) and so it was suggested that it be named CyHV-3. The virus induces gill necrosis and interstitial nephritis as early as 4-6 days post infection. The virus propagates well in the intestine and kidney and infected fish droppings contain high amounts of infectious virus. Thus, fish faeces is an appropriate source for non-invasive diagnosis by virus isolation in cell culture, PCR and ELISA tests. Strategies for controlling viral infection in fish are of limited use. Preventing introduction of CNGV into aquaculture facilities is desirable, but is not fail-safe. Live attenuated virus was developed in Israel and found to be an efficient and economic prophylactic vaccine. Morphologically CNGV
Pancreatic window and open necrosectomy; a surgical alternative for walled-off pancreatic necrosis in a second level hospital in Mexico

Walled-off pancreatic necrosis is defined as a necrotic collection with a defined wall, which generally occurs in 15% of patients in the fourth week after acute pancreatitis. Actually, open surgery is reserved for selected cases, with minimally invasive treatments such as image-assisted percutaneous drainage or endoscopic ultrasound being the procedures of choice. However, in developing countries the open approach continues to be an effective therapeutic alternative. We present the case of a 47-year-old male patient with no significant history who developed severe acute pancreatitis secondary to hypertriglyceridemia and who later developed walled-off pancreatic necrosis as a late complication. As a treatment, a debridement of the necrotic tissue with marsupialization was performed using the bradley III technique, secondary to the procedure, a pancreatic fistula was developed. After 8 weeks of hospitalization, in which he had a favourable response to surgical treatment, with spontaneous closure of the fistula without complications. Surgical management of late complications of acute pancreatitis remains controversial. Although minimally invasive procedures are the first option nowadays, in developing countries, open necrosectomy remains a good option for the treatment of these types of complications.
Biodistribution and Pharmacokinetics of

5-thio-D-glucose (5-TDG) exerts profound effects on rapidly metabolizing tissues. We have used liquid scintillation counting to study the tissue distribution and phar macokinetics of S-35-labeled 5-TDG in hamster models of pancreatic tumors. In the normal hamster, initial uptake of S-35 activity into kidney, liver, and blood was high, but rapidly decreased with time. The pancreatic uptake (% doseig) never exceeded 0.75%. This level occurredonly at the earliest timesafter administration. Uptake in all three tumor models exceeded that in pancreatic tissue within 15 mm of injection. The highest tumor-to-pancreas ratio was seen in the duct-tumor model, which also exhibited the most favorable tumor-to-tissue ratio when compared with kidney, liver, and muscle. Favorable ratios were most pronounced at 6 and 24 hr after injection. These studies provide impetus for the use of 5-TDG as a model compound for the
Level of ochratoxin A in cereal-flours in the Prishtina region

To assess food safety associated with the occurrence of ochratoxin A (OTA) residues in different kinds of flours, a survey was carried out during 2016–2017 in 5 municipalities of the Prishtina region (Prishtina, Gllogovc, Lipjan, Fushe Kosova, and Podujeve). In the present study, a total of 120 flour samples were collected, consisting of domestic and imported samples. The analytical method used in our study to measure the occurrence and concentration range of OTA in the samples was competitive enzyme-linked immunosorbent assay (ELISA) method. A method based on UHPLC-MS/MS was used to confirm the presence of ochratoxin A in samples in which the toxin was detected by ELISA. Out of all the samples examined, nine were contaminated with OTA. The frequency of OTA contamination in 2016 was 5 out of 75 samples (6.7%), and in 2017, 4 out of 45 samples examined (8.9%) were contaminated. OTA was detected in four wheat flour samples (9%), in four maize flour samples (14.8%) and in one rye flour sample (8.3%). The level of OTA ranged from 0.26 to 0.85 μg kg -1 in the four positive wheat samples, from 0.77 to 2.75 μg kg -1 in the four positive maize samples and the level was 0.77 μg kg -1 in the one positive rye sample. None of the contaminated samples exceeded the maximum levels (ML) of 3 μg kg -1 , set by to the European Union Regulation and Kosovo Food Codex.
Geometric Variation in the Surface Rupture of the 2018 Mw7.5 Palu Earthquake from Subpixel Optical Image Correlation

We obtained high-resolution (10 m) horizontal displacement fields from pre- and post-seismic Sentinel-2 optical images of the 2018 Mw7.5 Palu earthquake using subpixel image correlation. From these, we calculated the curl, divergence, and shear strain fields from the north-south (NS) and east-west (EW) displacement fields. Our results show that the surface rupture produced by the event was distributed within the Sulawesi neck (0.0974–0.6632°S) and Palu basin (0.8835–1.4206°S), and had a variable strike of 313.0–355.2° and strike slip of 2.00–6.62 m. The NS and EW displacement fields within the Palu basin included fine-scale displacements in both the near- and far-fault, the deformation patterns included a small restraining bend (localized shortening), a distributed rupture zone, and a major releasing bend (net extension) from the curl, divergence, and shear strain. Surface rupture was dominated by left-lateral strike-slip from initiation to termination, with a localized normal slip component peaking at ~3.75 m. The characteristics and geometric variation of the ruptured fault controlled both the formation of these surface deformation patterns and sustained supershear rupture.
Dimensions of dynamic marketing capability and export performance

Purpose The purpose of this paper is to develop a conceptual framework on the dimensions of dynamic marketing capability (DMC) and its relationship with export performance. The paper also proposes the mediating role of competitive hybrid strategy and the moderating role of environmental responsiveness in explaining the relationship between DMC and export performance. Design/methodology/approach By following the dynamic capability notion of the marketing and competitive strategy literature, this paper proposes a novel conceptualization of the DMC development process and the possible effect of DMC on attaining competitive advantage. Findings The paper postulates that a firm’s DMC can reflect complementary power when its higher-level marketing capabilities are bundled together to detect distributing channel members’ crucial needs, competitors’ action plans and satisfying market demand. As yet little is known about the main underlying dimensions of higher-level DMC construct, the paper contributes in proposing the key dimensions of DMC. Originality/value This research advances the knowledge-based view and resource-based views and evolves a solid foundation of DMC constructs comprising four higher-order marketing capabilities, namely, ambidextrous market orientation, customer relationship management capability, brand management capability and new product development capability. Thus, this paper contributes in DMC literature in explaining export performance.
A Novel Conformable Fractional-Order Terminal Sliding Mode Controller for a Class of Uncertain Nonlinear Systems

This paper proposes a conformable fractional-order terminal sliding mode controller for a class of nonlinear systems subject to uncertainties. First, a novel conformable fractional terminal sliding surface is proposed and its finite-time stability to the equilibrium point is proven. Subsequently, a switching function with a time-varying gain is presented. The system’s stability is guaranteed by the fractional-order Lyapunov stability theorem. The reaching and convergence time are analytically calculated. The designed controller has simple calculations. The control scheme improves the convergence speed, chattering phenomena, and control effort in the presence of disturbance and uncertainty. The simulation results show the efficiency of the proposed controller.
Relationships among Beliefs, Attitudes, Time Resources, Subjective Norms, and Intentions to Use Wearable Augmented Reality in Art Galleries

As a result of interactive and immersive technologies such as augmented reality, almost every service business has changed their ways of engaging with consumers. However, there has been little research on acceptance and use of wearable augmented reality (AR) in interactive services in museums and art galleries. Therefore, the aim of this study was to investigate the causal relationships among customers’ beliefs, evaluation, attitudes, perceived behavior control (time resources), subjective norms, and intentions to use wearable AR and visit a tourist attraction (an art gallery) using the theory of planned behavior. The results showed that time resources affected intention to visit an art gallery, while attitude toward wearable AR had an impact on intention to use wearable AR. Subjective norms were found to predict intentions, and the intention to use wearable AR was found to influence the intention to visit an art gallery.
Environmental and demographic factors influence the spatial genetic structure of an intertidal barnacle in central-northern Chile

Understanding the multiplicity of processes producing genetic patterns in natural populations can shed light on the ecology and evolution of species, and help guide effective management and conservation strategies. Here we investigated the role of environmental, demographic, and geographic factors in shaping the spatial patterns of genetic diversity and differentiation of the intertidal barnacle Notochthamalus scabrosus along the central-northern coast of Chile (28− 34° S). We analyzed genetic data from 7 microsatellite loci genotyped for 300 individuals sampled from 10 sites and combined this information with 8 site-specific environmental (4), demographic (2), and geographic (2) variables using least squares linear regressions, generalized linear models, and mat rix regression analyses. We found a strong association between the spatially structured genetic diversity of N. scabrosus and patterns of temporal variability in chlorophyll a, and among-site differences in seawater temperature and adult abundance. Our results illustrate that population size, partly driven by recruitment success, can leave a signal on genetic structure of this highly dispersive marine species. The significant effect of temperature and chlorophyll a stresses that local adaptation may be key to understanding the spatial genetic structure of our model species. Hence, the results of this work represent an advance towards understanding the usually complex causal relationships between environmental variables, gene flow, and genetic diversity patterns of coastal populations.
Výzkum významných zdrojů česko-saských přeshraničních podzemních vod

Zajimavým a užitecným tematem, ktere je možne řesit v ramci Evropske unie, je problematika přeshranicnich podzemnich vod. Podzemni vody jsou jako důležite vodni zdroje casto využivany na obou stranach spolecne statni hranice, a proto může dochazet k jejich přeshranicnimu ovlivněni.
Morphology and Optical Properties of Thin Cd3As2 Films of a Dirac Semimetal Compound

Using atomic-force microscopy (AFM) and wide-band (0.02–8.5 eV) spectroscopic ellipsometry techniques, we investigated the morphology and optical properties of Cd3As2 films grown by non-reactive RF magnetron sputtering on two types of oriented crystalline substrates (100)p-Si and (001) α-Al2O3. The AFM study revealed the grainy morphology of the films due to island incorporation during the film growth. The complex dielectric function spectra of the annealed Cd3As2/Al2O3 films manifest pronounced interband optical transitions at 1.2 and 3.0 eV, in excellent agreement with the theoretical calculations for the body centered tetragonal Cd3As2 crystal structure. We discovered that due to electronic excitations to the Cd(s) conical bands, the low-energy absorption edge of the annealed Cd3As2 films reveals a linear dependence. We found that for the annealed Cd3As2 films, the Cd(s) conical node may be shifted in energy by about 0.08–0.18 eV above the heavy-flat As(p) valence band, determining the optical gap value. The as-grown Cd3As2 films exhibit the pronounced changes of the electronic band structure due to the doping effect associated with Cd non-stoichiometry, where fine-tuning of the Cd concentration may result in the gapless electronic band structure of Dirac semimetals.
Efficient method for evaluation and hardware-in-loop testing of electro–optical tracking system

Abstract. Object tracking technology is being continually improved to ensure robust tracking performance under real conditions, such as cluttered background, fast motion, and lengthy occlusions. The performance of these video trackers depends significantly on evaluation methodologies adopted during the assessment of tracking algorithms. Most of these video trackers are evaluated using video sequences annotated with the simulated visual attributes of objects. Generating such sequences with the requisite attributes is laborious and time consuming. These annotated video sequences may fail to address real challenges; hence, the trackers must be tested using available opportunity targets in lengthy field trials. We present an innovative scheme for the hardware-in-loop testing of such video trackers for efficient evaluation under complex background scenarios. The designed simulator can provide the real-time visual characteristics of object parameters with a live background without halting the evaluation process. The proposed method facilitates the efficient evaluation of a closed-loop video tracker by providing a virtually endless video sequence containing realistic visual attributes of potential objects. In addition, the validation of the tracker’s performance in realistic scenarios, the comparative performance of tracking algorithms under varying operational conditions, and an in-depth analysis of the tracker system parameters are presented.
Renewable energy consumption and sustainable development in high-income countries

ABSTRACT This study aims to analyse the relationship between renewable energy, non-renewable energy, economic growth and sustainable development in high-income countries. This analysis uses data from 20 high-income countries covering the 1990–2015 period and finds that there is a cointegration relationship among the considered variables. According to the estimation of long-term coefficients for the cointegrated variables, renewable energy consumption has a statistically significant positive effect on sustainable development in the long run. In high-income countries, a 1% increase in renewable energy consumption increases sustainable development by 0.326%. In contrast, non-renewable energy consumption has a statistically significant negative effect on sustainable development in the long run. In high-income countries, a 1% increase in non-renewable energy consumption reduces sustainable development by 1.004%. According to the Granger causality estimates obtained in this study, renewable energy is the cause of sustainable development in both the short and long term. These findings demonstrate the importance of renewable energy consumption to sustainable development in high-income countries. Therefore, while high-income countries increase renewable energy consumption, they should decrease non-renewable energy consumption as much as possible.