Miracle-dz/UniFAR-FTUs huggingface dataset:
Meeting Teachers' and Learners' Perceptions on Mobile Learning: A Case of Indonesian Vocational High School in Surakarta City

Information and communication technology (ICT) has become the main resource to be devoted for most countries in this world. The government of Indonesia has made a regulation by the minister of education and culture in term of implementing curriculum 2013 which includes student center learning and scientific approach as the basis of ICT application. This study discusses the perception of teachers and learners regarding to the implementation of mobile learning in vocational high school. It is a mixed method study where undertakes interviews and surveys coming from two different schools. In analyzing the teachers and learners' perceptions towards implementation of mobile learning, it was used unified theory of acceptance and use of technology (UTAUT) as the guiding model. The data from the survey was analyzed by using SPSS, while finding the contributors key was done by applying percentage analysis. The findings showed that most of teachers and learners at vocational high school in Surakarta city are familiar with mobile ICT. They are capable to operate and use it for some purposes such as; downloading educational material, search for definitions of words or terms, and send assignments to accomplish the learning goals.
Characterization of miR-574-5p decoy to CUGBP1 in human lung cancer cells using a mass spectrometry proteomics approach

The bioactive lipid mediator prostaglandin (PG) E2 is generated by the enzyme microsomal prostaglandin E2 synthase-1 (mPGES-1). Especially in lung tumors, mPGES-1 was shown to be significantly overexpressed which contributes to a pro-tumorigenic microenvironment. Current medication interfering with the negative effects of PGE2 comprise only non-steroidal anti-inflammatory drugs (NSAIDs). While these have effective analgesic properties and are commonly used as pain killers, treatment of tumor growth is still inconclusive. Probably, only subgroups of cancer patients exhibit an abnormal prostanoid profile. Therefore, a reliable biomarker is necessary to identify patients who could benefit from said treatment. In a recent study, it was discovered that a specific microRNA (miR) can induce mPGES-1 gene expression. The miR-574-5p prevents binding of the inhibitory CUG-RNA binding protein 1 (CUGBP1) to the 3´ untranslated region (UTR) of mPGES-1. This non-canonical decoy function of miR-574-5p leads to an increased mPGES-1 protein level. Following, an induction of PGE2 formation triggers the progression of lung tumor growth in vivo. Interestingly, the entire influence on tumor progression could be blocked with the addition of a specific mPGES-1 inhibitor, confirming the huge influence of miR-574-5p on (patho-) physiological mPGES-1 functions. In this study, a proteomics approach was conducted in order to further characterize this decoy mechanism in human lung cancer cells. The aim was to gather global insights into the proteome changes related to miR-574-5p and CUGBP1, especially in a compartment specific manner. Further, it was aimed to identify new CUGBP1 targets and find out if they are also affected by the decoy function of miR-574-5p. Two new CUGBP1 targets were validated herein: NADH-Ubiquinone Oxidoreductase Core Subunit S2 (NDUFS2) and Mothers against decapentaplegic homolog 2 (SMAD2). However, both NDUFS2 and SMAD2 are independent from miR-574-5p levels. In a bioinformatical 3’UTR analysis of potential CUGBP1 targets, it was shown that the specific splicing pattern of mPGES-1 is unique, comprising two long CUGBP1 binding motifs with a 3’UTR intron in between. Only 11 other transcripts harbor a similar but not identical pattern in their sequence. Hence, it is assumable that this novel decoy mechanism is specifically regulating mPGES-1 in A549 lung cancer cells. This might be caused by the unique splice pattern of mPGES-1. However, further experiments are needed to confirm this hypothesis. Nevertheless, specificity of the decoy mechanism would open up new opportunities for lung cancer patients. By using miR-574-5p as a biomarker, one could stratify those patients with high mPGES-1 levels who have a higher chance to benefit from the anti-tumorigenic potential of NSAID therapy.
Floristics diversity composition along an altitudinal gradient in Himalayan chir pine forest of the western Himalayas

In the present study, we examined the species composition of Himalayan Chir Pine forest (Pinus roxburghii Sargent) at different altitudes between 1000-1600m asl, considering three altitudinal gradients viz., A1(Lower altitude: 1000-1200m); A2(Middle altitude: 1200-1400m); A3(Higher altitude: 1400-1600m) in the Western Himalayas. In this study, a total of 50 species were recorded, of which 9 were trees, 15 shrubs, 26 herbs. Herb plant richness (in number) showed a diminishing trend with altitude whereas shrub species remain same for low and mid altitudes with slight drop in high altitudes and the tree species richness remain constant for all the altitudes. Many types of environmental changes (altitudes, slopes, aspect, temperature, precipitation etc.) influence the processes that can both augment or erode diversity. The study suggests that species distribution, presence of the particular species (species composition) and number of species present (species richness) are largely regulated by altitudes and other climatic + topographic factors.
Relative contribution of five species of herbivorous fish to the consumption of epilithic algal matrix in the southern Great Barrier Reef

The importance of herbivorous organisms to the ecology of coral reef systems has been well documented, with most studies concentrating on the visually conspicuous families of Pomacentridae, Scaridae, Acanthuridae and Siganidae. Recent studies have shown that the visually cryptic fish from the tribe Salariini (Blenniidae) may also be important contributors to the maintenance of coral reef ecosystems. Herbivores are thought to play a key role in suppressing the growth of algae and allowing space for new corals to settle and grow, keeping coral reef systems coral-based. The principle algal food source utilised by herbivorous organisms in coral reef systems is the epilithic algal matrix (EAM). It consists of a turf algae mat with associated detritus, meiofauna, phytoplankton, bacteria and sediment baffled among the fronds. To determine the relative contributions of representative herbivorous fishes from the above-mentioned families to the consumption of EAM on Heron Island reef, the abundance, biomass, distribution, morphology, assimilation efficiency, behaviour and grazing contribution were investigated. To address concerns of past studies investigating the importance of herbivorous blermies in coral reef systems, the numerical abundance, biomass and distribution of Salariini blenny assemblages at Heron Island, Lady Elliot and North West reefs were compared. Species composition and biomass, but not density differed significantly among the three reefs. At Heron Island reef, density and biomass of combtoothed blermies exceeded published estimates by 27% 98% for most groups of conspicuous herbivorous fish in equivalent zones indicating that inconspicuous grazers deserve closer attention. At Heron Island reef, biomass densities and mean wet mass of Ward's damselfish Pomacentrus wardi and the jewelled blenny Salarias fasciatus were not significantly different, whereas total bites per day, epilithic algal matrix (EAM) per bite and total organic carbon consumed by S. fasciatus significantly exceeded those of P. wardi. Territorial behaviour differed between the two species. The damselfish P. wardi spent most of the time chasing roving grazers fi-om their territories, while largely ignoring blennies. While, S. fasciatus chased more than c. 90% of other blennies from their territories, largely ignoring (or avoiding) roving grazers. Both P. wardi and S.
Bees colonies for detecting communities evolution using data warehouse

The analysis of social networks and their evolution has gained much interest in recent years. In fact, few methods revealed and tracked meaningful communities over time. These methods also dealt efficiently with structure and topic evolution of networks. In this paper, we propose a novel technique to track dynamic communities and their evolution behaviour. The main objective of our approach and using the artificial bee colony (ABC) is to trace the evolution of community and to optimise our objective function to keep proper partitioning. Moreover, we use a data warehouse as a mind of bees to store the information of different communities structure in every timestamp. The experimental results showed that the proposed method is efficient in discovering dynamics communities and tracking their evolution.
Review of wound ballistic research and its applicability to wildlife management

Wound ballistics is a science that has been gaining attention in wildlife management because of the movement toward non-lead bullets for hunting and wildlife management projects. Wildlife biologists and managers are interested in evaluating new bullet technologies and using traditional bullets outside of their initial design parameters; however, much of the background and science that is involved in a wound ballistic study is outside of a typical wildlife biologist's training. I present a review of major wound ballistic history and background, including theories of how bullets wound and kill, and I review the primary techniques used for wound ballistic research. I found that most of the wound ballistic literature is found in a wide range of publications in both gray and primary literature; however, little work has been published that uses these techniques to investigate wound ballistics for wildlife management. Many of the techniques described for assessing the terminal ballistic for medical, military, and law enforcement purposes can be applied in the wildlife management field. © 2013 The Wildlife Society.
Oleanolic acid administration alleviates neuropathic pain after a peripheral nerve injury by regulating microglia polarization-mediated neuroinflammation

Neuropathic pain caused by a peripheral nerve injury constitutes a great challenge in clinical treatments due to the unsatisfactory efficacy of the current strategy. Microglial activation-mediated neuroinflammation is a major characteristic of neuropathic pain. Oleanolic acid is a natural triterpenoid in food and medical plants, and fulfills pleiotropic functions in inflammatory diseases. Nevertheless, its role in neuropathic pain remains poorly elucidated. In the current study, oleanolic acid dose-dependently suppressed LPS-evoked IBA-1 expression (a microglial marker) without cytotoxicity to microglia, suggesting the inhibitory efficacy of oleanolic acid in microglial activation. Moreover, oleanolic acid incubation offset LPS-induced increases in the iNOS transcript and NO releases from microglia, concomitant with the decreases in pro-inflammatory cytokine transcripts and production including IL-6, IL-1β, and TNF-α. Simultaneously, oleanolic acid shifted the microglial polarization from the M1 phenotype to the M2 phenotype upon LPS conditions by suppressing LPS-induced M1 marker CD16, CD86 transcripts, and enhancing the M2 marker Arg-1 mRNA and anti-inflammatory IL-10 levels. In addition, the LPS-induced activation of TLR4-NF-κB signaling was suppressed in the microglia after the oleanolic acid treatment. Restoring this signaling by the TLR4 plasmid transfection overturned the suppressive effects of oleanolic acid on microglial polarization-evoked inflammation. In vivo, oleanolic acid injection alleviated allodynia and hyperalgesia in SNL-induced neuropathic pain mice. Concomitantly, oleanolic acid facilitated microglial polarization to M2, accompanied by inhibition in inflammatory cytokine levels and activation of TLR4-NF-κB signaling. Collectively, these findings confirm that oleanolic acid may ameliorate neuropathic pain by promoting microglial polarization from pro-inflammatory M1 to anti-inflammatory M2 phenotype via the TLR4-NF-κB pathway, thereby indicating its usefulness as therapeutic intervention in neuropathic pain.
A GENERIC formalism for Korteweg-type fluids: II. Higher-order models and relation to microforces

In this paper, a second order model for Korteweg-type fluids is derived within the GENERIC formalism, whose standard application to Korteweg-type fluids is studied in detail in Part I of this series of papers. The higher-order model contains the second-order gradient of the density in the constitutive relation concerning internal energy, and the resulting Korteweg stress covers the original model proposed by Korteweg. This is in contrast to the model derived by Dunn and Serrin, which lacks the term of the second-order gradient of density. The higher-order model is thermodynamically consistent and includes interstitial working, as in Dunn and Serrin’s model. The GENERIC formalism provides a fairly simple derivation of higher-order models for Korteweg-type fluids. Another possible formulation based on the concept of microforces introduced by Gurtin is also presented and discussed in relation to the GENERIC formalism.
A pictorial key to current genus groups of 'Rhabditidae'

A pictorial key to the identification of 38 genus taxa as well as the species groups of five genera of rhabditids is presented in five plates. Four character complexes are used in the key, namely lip region and stoma, posterior body region of both sexes, and spicules and gubernaculum.
Mitochondria Protein Import: Methods

Mitochondria are prominent and essential organelles within eukaryotic cells. The majority of proteins residing within mitochondria are nuclear-encoded and consequently synthesised as precursor proteins on cytosolic ribosomes. These precursors must be imported across one or both of the mitochondrial membranes to reach their final destination where they can acquire their functional state. Currently we have knowledge of at least four different pathways that govern the import and sorting of nuclear-encoded mitochondrial precursors. The elucidation and characterisation of these pathways has been greatly facilitated by the in vitro mitochondrial import assay. The in vitro assay is the main biochemical approach for analysing protein import into mitochondria and is performed by incubating a radiolabelled precursor protein with isolated mitochondria. Key Concepts: Most mitochondrial proteins are encoded by nuclear DNA and need to be imported into the organelle following translation. Different pathways exist for the import of proteins into the various mitochondrial subcompartments. In vitro translated precursors can be imported into energised isolated mitochondria. The final residence of the imported precursor can be analysed using various treatments. In vitro import reactions can be accompanied with monitoring the assembly of the precursor into complexes. Keywords: in vitro import assay; TOM; TIM; MIA; SAM precursor protein; translocation
In Vitro Inhibition of Beauveria bassiana (Bals.) Vuill. Growth by Different Commonly Used Insecticides in Rice

In vitro inhibition of 13 different insecticides and one botanical on Beauveria bassiana growth was tested. Two doses of chemical insecticides, one at recommended dose (RD) and another at half of recommended dose (½. RD) and for botanicals three doses, first one at recommended and one at ½ and another at ½ of the recommended dose were tested. 100 per cent of mycelial growth was observed when the entomopathogen was grown in presence of monocrotophos (0.31%) and dichlorvos (0.12%). Cypermethrin, deltamethrin, alphamethrin and phosphamidon at recommended dose showed growth inhibition of < 50 per cent. Half of the recommended dose of deltamethrin was found having lowest inhibition (14.06 %).
Numbers conceal the intricacies in categorising qualitative research in organisational studies: What lies beneath the surface?

However, it is generally accepted that qualitative researchers use text rather than numerical data and analyse those data in their textual form rather than in statistics to convert them to numbers (Carter & Little, 2007; Morgan, 2018). Therefore, the view that qualitative research is concerned with non-numerical data is not necessarily incorrect (Anyan, 2013; Aspers & Corte, 2019; Chesebro & Borisoff, 2007). However, qualitative research should not be categorised primarily based on whether the study uses non-numerical data per se, but by the theoretical underpinnings of research, which exemplify the researcher’s worldview or set of beliefs about the world (Evered & Louis, 1981). Brown (1980) maintains that to qualify a study as qualitative or quantitative only because quantitative data have been used is a misconception. This view resonates with Maxwell’s (2010) contention that numerical and non-numerical data cannot be useful ways to distinguish between qualitative and quantitative research. Therefore, the characterisation of research as qualitative because it does not rely on numerical data or statistics is expedient, but tends to conceal the intricacies implicit in such a categorisation. Orientation: The characterisation of research as qualitative because it does not use statistics is expedient but tends to conceal the intricacies implicit in such a categorisation. Many novice researchers believe that qualitative research is limited to non-numerical data.
Sustainable Production of Nannochloris atomus Biomass Towards Biodiesel Production

Nannochloris atomus (QUCCCM31) is a local marine microalga showing potential to serve as renewable feedstock for biodiesel production. The investigation of the impact of temperature variation and nitrogen concentrations on the biomass and lipid productivities evidenced that biomass productivity increased with the temperature to reach an optimum of 195 mgL−1 d−1 at 30 °C. Similarly, the lipid content was strongly influenced by the elevation of temperature; indeed, it increased up to ~3 folds when the temperature increased from 20 to 40 °C. When both stresses were combined, triacylglycerols and lipid productivity reached a maximum of 45% and 88 mgL−1 d−1, respectively at 40 °C. Cultures under high temperatures along with Nitrogen-Depleted (ND) favored the synthesis of Fatty Acids Methyl Ester (FAMEs) suitable for high quality biodiesel production, whereas cultures conducted at low temperature coupled with Nitrogen-Limited (NL) led to a production of polyunsaturated fatty acids (PUFAs). Our results support the feasibility of cultivating the thermotolerant isolate QUCCCM31 year-round to meet the sustainability challenges of algal biomass production by growing under temperature and nitrogen variations. The presence of omega 3 and 9 fatty acids as valuable co-products will help in reducing the total process cost via biorefinery.
Half-life Estimation of Encapsulated Enterococcus faecium IS-27526 by Accelerated Shelf Life Testing (ASLT)

Probiotics are live microbes with beneficial effect to the host when administrated in adequate quantities. Ensuring the functionality of probiotics can be a challenge for manufacturers due to harsh environment conditions during processing, handling and storage. Enterococcus faecium IS-27526 is one of novel probiotic strain isolated from dadih, traditional fermented buffalo milk of West Sumatra. The purpose of this study was to determine the effect of microencapsulation, moisture absorber, and storage temperature on the half-life of probiotic powder estimated by Accelerated Shelf Life Testing (ASLT). There were two treatment groups, namely free cell (FC), and microencapsulated cell (EC), with additional treatment in each group, with addition of moisture absorber (MA) and without moisture absorber, stored at various temperatures (5°C, 27°C and 37°C) for 21 days and viable counts was assessed every 7 days. Storage temperature significantly affects the half-life of probiotic powder (p<0.05). At 5°C, EC significantly showed longer half-life than EC-MA, 140.14 ± 5.701 and 113.45 ± 3.242 days, respectively, at 27°C, EC significantly shorter half-life than EC-MA, 38.64 ± 6.831 and 42.35 ± 0.973 days, respectively. Microencapsulation and moisture absorber didn’t show significant effect on half-life (p>0.05) at various temperature storage.
Estimation of Evapotranspiration of a Jujube/Cotton Intercropping System in an Arid Area Based on the Dual Crop Coefficient Method

An accurate estimation of crop evapotranspiration (ETc) in intercropping is critical for a theoretical basis for formulating an intercropping irrigation system of fruit trees and improving the soil moisture condition of orchards in arid regions of Southern Xinjiang. Herein, observational data such as soil moisture and plant physiological indicators were measured in jujube/cotton intercropping in the Aksu region from 2015 to 2017. The evapotranspiration of single-crop jujube and cotton was estimated using the modified dual crop coefficient method. Then, based on the proportion of intercropping crops, the soil water stress coefficient was introduced to estimate the evapotranspiration of the jujube/cotton intercropping. The results show that the model has good applicability to simulate single-crop jujube and cotton, and jujube/cotton intercropping. However, compared with single cropping, the accuracy of simulated daily evapotranspiration was decreased. In addition, adjusting the cotton irrigation amount caused the simulation accuracy to further decrease. From the perspective of interspecies complementarity and competition, cotton dominated the intercropping system and had better tolerance to external environmental changes than jujube trees. Intercropping had negative effects on jujube trees in general, and very obvious positive effects on cotton. Based on the 3-year crop yield, 5-year-old jujube trees are recommended for intercropping. During this time, the yield of cotton under the effect of interspecific complementation increased by 26.47%, and the yield of intercropping jujube was similar to that of single crop. As the jujube tree age increases, the effect of increasing cotton production gradually diminishes. The jujube trees also had a significant reduction in yield due to interspecific competition. Our research supports the dual crop coefficient method as appropriate to estimate crop ETc in intercropping and may be further used to improve irrigation scheduling for jujube/cotton intercropping.
Modulatory Effect of Serotonergic System in Pentylenetetrazole-Induced Seizures and Associated Memory Deficit: Role of 5-HT1A and 5-HT2A/2C

Background and Purpose Recent studies have recognised the memory deficit as one of the most common psychiatric issues in the patients with epilepsy, which severely affects the quality of life. Our previous studies have demonstrated the possible involvement of serotonergic system in the pathogenesis of epilepsy and associated memory deficit. The possible involvement of 5-HT1A and 5-HT2A/2C receptor has not been explored yet. Therefore, this study has been envisaged to explore the effect of 5-HT1A and 5-HT2A/2C receptor modulation on epilepsy and memory deficit in pentylenetetrazole-kindled mice. Methods In the present experimental approach, we examined the efficacy of modulation of 5-HT1A and 5-HT2A/2C receptor in pentylenetetrazole-induced kindling in male Swiss mice (n=75). Mice were kindled by sub-convulsive dose of pentylenetetrazole (35 mg/kg, intraperitoneal injection), at the interval of 48±2 hours). Successfully kindled animals were treated with 5-HT1A and 5-HT2A/2C receptor modulators. The effect of different treatments on seizure severity score and memory impairment was analysed. Results 5-HT1A receptor agonist improved the memory functions while seizure severity was not improved, and the opposite effect was observed with 5-HT1A receptor antagonist. On the other hand, 5-HT2A/2C receptor agonist significantly improved memory deficit as well as seizure severity in the kindled animals. Conclusions The outcome of the study indicates the possible involvement of 5-HT2A/2C receptor in the pathogenesis of epilepsy and associated memory deficit, which can be further explored for its management.