Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessment of the evolution of malaria and intestinal helminthes infections from 1983 to 2014 in the Hevecam agroindustrial complex, south region of Cameroon

Man-made development projects have usually been pointed to significantly influence the epidemiological features of communicable parasitic diseases in sub-Saharan countries as a result of anthropogenic environmental changes. This study aimed to assess the current health status of dwellers of the Hevecam agroindustrial complex established after rainforest deforestation in Southern Cameroon, and to monitor its evolution compared to data collected 31 years ago. A prospective cross-sectional study was carried out in 2014 in the same four villages which were previously investigated 31 years ago in the Hevecam area. Assessment focused on prevalence of malaria and soil-transmitted helminthiasis, and the risk factors of these diseases. Present data were then compared with those collected in 1983. Data from four villages investigated indicated that malaria and soil-transmitted helminthiasis were mesoendemic and hypoendemic, respectively in the area. The malaria endemicity level was similar in either study village according to both parasitological results and spleen index. Plasmodium falciparum and Plasmodium malariae caused 98.8 and 1.2% of malaria cases recorded. P. falciparum parasites loads ranged from light to heavy. Prevalence rates of Plasmodium carriage were significantly influenced by sex, age and occupation. Intestinal helminths parasites occurred in 14.1% subjects. The main infective agents were Ascaris lumbricoides and Trichuris trichiura, found either as monospecfic or mixed infections. A. lumbricoides infections were the most frequent. Helminths intensities of infections were predominantly light. Prevalence significantly varied with villages, age, occupation and regular deworming status. Mixed infections by malaria and helminths parasites were recorded in some subjects. Comparing current to previous data, malaria and intestinal helminthiasis have evolved significantly in divergent ways in 31 years within the Hevecam villages. Malaria infections increased from hypoendemic to mesoendemic, while intestinal helminth infections decreased from hyperendemic to hypoendemic. Evolution of these diseases indicated a need for health facilities located in Hevecam to improve specific control measures for malaria and sustained helminth control tools. Key words: Malaria, intestinal helminthiasis, prevalence, evolution, Hevecam.
Partial characterization and cloning of the genome of PvSNPV ( = BP-type virus ) pathogenic for Penaeus vannamei

PvSNPV isolated from the shrimp Penaeus rtannamei was characterized after purif~cation. In negatlve staining, the rod-shaped, enveloped particles were 312 to 320 nm in length and 75 to 87 nm In diameter. The nucleocapsids, 306 to 312 nm in length and 62 to 68 nm in diameter, showed a crosshatched surface arranged in a helical pattern and a trilaminar structure capping both extremities. Purified occlusion body subunits (polyhedrin subunits) were 17 to 19 nm in diameter and, in SDS-PAGE, demonstrated 1 major polypeptide of 52 kDa. BamHI digested viral genome revealed a t least 7 different fragments. Cloning of these DNA fragments, and the resulting study of them, revealed the presence of 2 more fragments which had CO-migrated in gel electrophoresis. The cloned fragments, which represent about 40% of the estimated size of the genome, were characterized by their size and by the position of restriction sites. When the cloned fragments were labeled and used a s probes, no homology was found among the different inserts These gene probes reacted with different BP-type strains, but not with uninfected shrimp tissue The gene probes also did not react with shrimp tissues Infected with other shrimp viruses, indicating their specificity for the BP-type viruses.
Sequencing of antineoplastic drug administration: contributions to evidence-based oncology nursing practice

The objective of this study was to find scientific evidence of drug interactions between antineoplastic drugs that result from the administration sequence and then describe the best sequence and discuss its applicability to nursing care systematization (NCS). An integrative review of the literature was carried out in 2018 in the MEDLINE, LILACS, CINAHL, and BVS databases, with the terms neoplasms, drug Therapy, drug Interactions, chemotherapy, and sequence of administration. Fifty-seven studies were analyzed, which, as a set, studied 40 combinations of antineoplastic drugs and found pharmacokinetic and pharmacodynamic interactions resulting from the sequence of administration, which supported the construction of a chart that indicates the best sequence for each of those combinations. Along with the chart, a flowchart was also made to support NCS in the context of evidence-based oncology nursing practice. Selecting the sequences of antineoplastic drug administration is a new conceptual strategy designed for nurses who carry out multidrug therapy. Descriptors: Drug Therapy, Combination; Drug Interactions; Neoplasms; Oncology Nursing. 1 Nurse. Student in the graduate program in nursing at the Fluminense Federal University, master’s level. Nurse at the National Cancer Institute, Rio de Janeiro, RJ, Brazil. Email: angeloprimax@gmail.com. 2 Nurse and psychologist, PhD in nursing. Associate professor at the Fluminense Federal University, Rio de Janeiro, RJ, Brazil. Email: elianeramos.uff@gmail.com. 3 Nurse, PhD in collective health. Guest professor, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil. Email: carinne.mag@gmail.com. 4 Nurse, PhD in health care sciences. Guest professor in the Hospital Pharmacy Residence course at the Fluminense Federal University, Rio de Janeiro, RJ, Brazil. Email: bruna.barreto07@gmail.com. 5 Nurse, master’s in nursing. Nurse at the National Cancer Institute, Rio de Janeiro, RJ, Brazil. Email: ticypinto@gmail.com. 6 Nurse and psychologist, PhD in nursing and PhD in social psychology. Associate professor at the Fluminense Federal University. Niterói, RJ, Brazil. Email: roserosauff@gmail.com. Received: 04/02/2017. Accepetd: 10/19/2018. Published: 12/31/2018.
Fast fourier transformation of emitted noises from welding machines and their classification with acoustic method

G. Gokmen*, O. Akgun**, T.C. Akinci***, S. Seker*** *Marmara University, Department of Mechatronics Engineering, Istanbul, Turkey, E-mail: gokhang@marmara.edu. tr **Marmara University, Department of Computer Engineering, Istanbul, Turkey, E-mail: oakgun@marmara.edu. tr ***Istanbul Technical University, Department of Electrical Eng., Istanbul, Turkey, E-mail: akincitc@itu.edu. tr ***Istanbul Technical University, Department of Electrical Eng., Istanbul, Turkey, E-mail: sekers@itu.edu. tr
Biomimetic application of phosphatidylserine and PEGylated phosphatidylserine for macrophage polarization

і LIST OF CONTENTS . iv INTRODUCTION . 1 MATERIALS AND METHODS . 9 1. PSLs preparation and PEGylation . 9 2. Titanium disc surface modification . 11 3. RAW 264.7 cell culture . 11 4. Real-time polymerase chain reaction analysis of gene expression . 13 5. ELISA detection of cytokines . 14 6. Fluorescence-activated cell sorting analysis . 15 7. Live cell imaging . 15 8. Fluorescence recovery after photo-bleaching . 16 9. Cell adhesion and proliferation assay . 16 10. Scanning electron microscope (SEM) . 17 11. Immunofluorescence analysis . 17 12. Statistical analysis . 18 RESULTS . 19 1. The effects of PSLs and PEGylated PSLs
Novel physiological and metabolic insights into the beneficial gut microbe Faecalibacterium

Faecalibacterium prausnitzii is one of the most abundant commensal microbes in the human gut. It is an important supplier of butyrate to the colonic epithelium, and low numbers of faecalibacteria have been associated with severe inflammatory bowel disease. Previous studies revealed that F. prausnitzii shuttles electrons extracellularly to oxygen in systems containing flavins and thiols. Since this electron shuttling to oxygen strongly stimulates growth, the present studies were aimed at elucidating the role of riboflavin as an extracellular electronophore of F. prausnitzii . We show that F. prausnitzii can use riboflavin as a mediator for extracellular electron transfer to the anode of microbial fuel cell systems. However, this bacterium relies on exogenous riboflavin since it does not secrete this compound as shown by the analysis of spent growth medium using cyclic voltammetry. Importantly, cyclic voltammetry showed that riboflavin can undergo fully reversible redox cycling under physiologically relevant conditions. Lastly, riboflavin is shown to mediate the electrochemical oxidation of the main bacterial reducing equivalent NADH. Based on our present observations we hypothesize that riboflavin is of major importance as a redox mediator for bacterial extracellular electron transfer and growth in the human gut.
User Centred Methods for Measuring the Quality of Open Data

A project to identify metrics for assessing the quality of open data based on the needs of small voluntary sector organisations in the UK and India. We used small structured workshops to identify users’ key problems and then worked from those problems to understand how open data can help address them and what the key attributes must be for successful use. We then piloted different metrics that could be used to measure the presence of those attributes. This user-centred approach to open data research highlighted some fundamental issues with expanding the use of open data from its enthusiast base.
Ja n 20 19 G AME THEORETIC MODELLING OF INFECTIOUS DISEASE DYNAMICS AND INTERVENTION METHODS : A MINI-REVIEW

We review research papers which use game theory to model the decision making of individuals during an epidemic, attempting to classify the literature and identify the emerging trends in this field. We show that the literature can be classified based on (i) type of population modelling (compartmental or network-based), (ii) frequency of the game (non-iterative or iterative), and (iii) type of strategy adoption (self-evaluation or imitation). We highlight that the choice of model depends on many factors such as the type of immunity the disease confers, the type of immunity the vaccine confers, and size of population and level of mixing therein. We show that while early studies used compartmental modelling with self-evaluation based strategy adoption, the recent trend is to use network-based modelling with imitation-based strategy adoption. Our review indicates that game theory continues to be an effective tool to model intervention (vaccination or social distancing) decision-making by individuals.
RISK FACTORS AND PREVENTIVE MEASURES AGAINST URINARY TRACT INFECTION BY SHAFQUAT ALI KHUHRO AND BADARUDDIN A. MEMON

Urinary-tract infections are among the most common entities encountered in medical practice. Urinarytract infections, including cystitis, pyelonephritis, asymptomatic bacteriuria, and acute urethral syndrome, constitute one of the most frequent causes of illness in humans. The goal of this review is to provide an up to date summary of the literature with particular attention to practical questions about risk factors and preventive measures of urinary tract infection. --------------------------------------------------------------------------------------------------------------------------------
Photodegradation of Phenol using N-doped TiO

Phenol (C6H5OH) is a common contaminant in wastewater. In certain concentrations, phenol can inhibit the activity of microorganisms and give adverse effects to human health, such as liver and kidney damage, perfect heart rate, and lower blood pressure. In this study, phenol was degraded with and without N-doped TiO2 under photolysis UV-light (10 Watts, λ = 365 nm) and visible-light (13 watt Philips, lux= 1400, λ = 465-640 nm) irradiation. The reduction of phenol concentration was measured by a UV-Vis spectrophotometer at a wavelength 200-400 nm. Some parameters such as catalyst dose, irradiation times and type of light sources were studied. The XRD and DRS UV-Vis characterization confirm that the nitrogen modified of titania catalyst potentially actives in visible-light. The N-doped TiO2 is able to catalyze and improve the efficiency of phenol degradation in photocatalysis system. Phenol with initial concentration 8 mg/L was degraded by 30.51% and 33.89% without catalyst and increased to be 67.80% and 90.8% by addition of 15 mg N-doped TiO2 catalyst under visible-light and UV-light for 210 minutes photolysis, respectively. From the results, irradiation using UV-light achieves higher efficiency than visible-light on phenol degradation.
Design of Variable-Speed Dish-Stirling Solar–Thermal Power Plant for Maximum Energy Harness

Analysis on a developed dynamic model of the dishStirling (DS) system shows that maximum solar energy harness can be realized through controlling the Stirling engine speed. Toward this end, a control scheme is proposed for the doubly fed induction generator coupled to the DS system, as a means to achieve maximum power point tracking as the solar insolation level varies. Furthermore, the adopted fuzzy supervisory control technique is shown to be effective in controlling the temperature of the receiver in the DS system as the speed changes. Simulation results and experimental measurements validate the maximum energy harness ability of the proposed variable-speed DS solar–thermal system.
Annual Cycle of Turbulent Dissipation Estimated from

The rate of dissipation of turbulent kinetic energy is estimated using Seaglider observations of vertical water velocity in the midlatitude North Atlantic. This estimate is based on the large-eddy method, allowing the use of measurements of turbulent energy at large scales O(1–10 m) to diagnose the rate of energy dissipated through viscous processes at scales O(1 mm). The Seaglider data considered here were obtained in a region of high stratification (1 × 10−4 < N < 1 × 10−2s−1), where previous implementations of this method fail. The large-eddy method is generalized to high-stratification by high-pass filtering vertical velocity with a cutoff dependent on the local buoyancy frequency, producing a year-long time series of dissipation rate spanning the uppermost 1,000 m with subdaily resolution. This is compared to the dissipation rate estimated from a moored 600 kHz acoustic Doppler current profiler. The variability of the Seaglider-based dissipation correlates with one-dimensional scalings of windand buoyancy-driven mixed-layer turbulence. Plain Language Summary Measuring ocean turbulence is crucial for understanding how heat and carbon dioxide are transferred from the atmosphere to the deep ocean. However, measurements of ocean turbulence are sparse. Here autonomous Seagliders are used to estimate turbulence in the surface kilometer of the North Atlantic Ocean. Using an estimate of the vertical water velocity from the flight of the Seaglider through the water, we estimate turbulence by assuming the energy of the largest turbulent fluctuations is representative of the energy dissipated at molecular scales. This approach has been used previously in an ocean region where the vertical gradient of density is small. Our results show that this previous approach fails when the vertical density gradient increases, as it does not account for other processes that are unrelated to turbulence. We introduce a generalized method that isolates only the turbulent processes by accounting for the strength of the vertical density gradient. We show that this new estimate agrees with other turbulence measurements. Our estimate also agrees well with a simple estimates of turbulence from atmospheric processes. This study therefore presents method that can be applied to existing and new Seaglider data to greatly increase our measurements of ocean turbulence.
METODOLOGIA E TÉCNICAS EXPERIMENTAIS ESTIMATION OF GENETIC PARAMETERS IN THE SQUARE LATTICE ANALYSIS ( 1 )

This paper shows how to obtain unbiased estimates of genetic parameters of base populations, e.g., genotypic variance among families, heritability on a family mean basis, genotypic correlation and direct and indirect expected genetic gains, when the sampled families were evaluated in square lattice experiment. The theoretical part presents the variance and covariance components of the intra-block analysis of square lattice and the estimators of the components associated to treatment effect, considering the ordinary least squares method. In the analysis with treatments not corrected for blocks/replications, the estimator of the component due to treatment effect is equal to that of the analysis considering the complete block model. Experimental data from a breeding program of Eucalyptus pyrocarpa were used for genetic analysis. The high estimates of narrow sense heritabilities and additive genetic correlation, related to height and diameter, indicate that selection of the superior families will be effective in changing the means of the base population.
On the dynamic programming approach for the 3 D Navier-Stokes equations

The dynamic programming approach for the control of a 3D flow governed by the stochastic Navier-Stokes equations for incompressible fluid in a bounded domain is studied. By a compactness argument, existence of solutions for the associated Hamilton-Jacobi-Bellman equation is proved. Finally, existence of an optimal control through the feedback formula and of an optimal state is discussed.
Application for sentiment and demographic analysis processes on social media

Consumers used to make their complaints via phone and mail before the concept of social media was developed. Now, consumers have begun to state their wishes and complaints concerning companies using social media, and the firms’ adaptation to social media has been increased. Understanding the negative and positive attitudes of customers towards ads and questions has gained utmost importance for the companies’ decisions to be made for the future. Today, companies are able to continue their existence in the modern world’s competitive environment by adjusting their advertising and marketing strategies and calculating their budgets to social media analyses they get. In addition, companies depend on those analyses in order to determine their positions in the market and create their action plans. In this study, instant messages sent on social media and demographic information were used in the data analysis in order to determine whether those messages included positive or negative attitudes.
Features of structural-morphological changes in cases of experimental intestinal antibiotic-induced dysbiosis

Nowadays, scientists often define dysbiosis as a condition of a microbial ecological system, in which there is a simultaneous abnormality of the functions and interaction mechanisms of its key components: macroorganism and indigenous microbiota associated with the mucous membranes of cavities and skin. At the same time, obviously, the basis of all these processes is changes of structural intestinal components that are caused by qualitative and quantitative changes in the normal microflora. Purpose: to study the ultrastructural organization of the mucous membrane of the small intestine of mice after the formation of dysbiosis of the intestine. Outbred white mice in the number of 40 units (20 experimental and 20 control) was served as an experimental model. Antibacterial drugs (ampicillin, metronidazole and gentamicin) are used to form dysbiosis. The conducted experiments are allowed to establish that the using of antibacterial drugs in the above-mentioned doses contributes to shortening the length of the microvillus and their reduction (disappearance) in some places, destruction with subsequent disintegration. According to the results of electronograms analysis, the assumption was made about stimulating the secretory function of the small intestine enterocytes by powerful doses of antibacterial drugs. In addition, it was found that the formation of dysbiotic disorders is accompanied by a defect of the connection between epithelial cells due to the expansion of the intercellular space and the disappearance of the dense plate. Research results also indicate that antibiotics that were used in the experiment can cause development of apoptosis. In addition, it has been shown that, on the background of the dysbiotic disorders formation, the activation of immune processes is taking place, as evidenced by the appearance of a significant number of Paneth cells, plasma cells with enlarged tubules, apparently due to their filling with immunoglobulins, as well as the growth of numbers of luminalis eosinophils and basophils. The ability of antibiotics to form dysbiotic states with pronounced cytodestructive disorders in the epithelium of the small intestine with the development of apoptosis was substantiated; the argument about the immune stimulating effect of antibiotic induced dysbiosis is argued.
Current Treatment of Famil ial Hypercholesterolaemia

Familial hypercholesterolaemia (FH) is an autosomal-dominant disorder associated with mutations in the LDL receptor (LDLR) gene resulting in markedly elevated plasma low-density lipoprotein cholesterol (LDL-C) levels and premature atherosclerotic cardiovascular disease (ASCVD). Heterozygous FH (HeFH) (mutation in one allele) is associated with plasma LDL-C levels >190 mg/dl, whereas homozygous FH (HoFH) (mutation in both alleles) is associated with plasma LDL-C levels >500 mg/dl. As a result, there is a 20-fold increase in risk of premature coronary heart disease (CHD) in untreated patients compared to control. HeFH patients usually develop CHD before age 55 and 60 respectively for men and women without treatment. HoFH patients, however, develop CHD very early in life and can die before age 20 without treatment.
MICROBIAL COMMUNITIES AND ENZYME ACTIVITY FOR DIFFERENT RECLAMATION ( ECOLOGICAL RESTORATION ) PATTERNS OF ABANDONED FARMLANDS IN SHIHEZI , XINJIANG

Although there have been obvious land use changes in Xinjiang, China, the effect of reclamation (ecological restoration) of abandoned farmlands on soil microbial properties is rarely reported. Natural restoration of abandoned farmland was used as a control treatment, and the effects of different reclamation (ecological restoration) patterns on soil microbial properties in Shihezi, Xinjiang, China were analyzed. The results showed that there was a significant difference between different reclamation (ecological restoration) patterns in soil chemical and microbial characteristics (P < 0.05). These results indicate that the highest values for soil organic matter and available P were in accordance with the highest values for soil microbial communities (fungi, bacteria and total microbial amount), and the higher the value of pH, the lower the activity of urease and soil microbial biomass carbon. Land use patterns, both ecological restoration and reclamation types, were useful when only soil quality improvement was considered. Because of the advantages of improvement in soil fertility, the agroforestry pattern could be used as the preferred reclamation pattern for abandoned farmland in salinized regions. By increasing the soil water content and promoting the establishment of vegetation, the water recharge pattern could be a good choice during the early stage of ecological restoration of abandoned farmland.