Miracle-dz/UniFAR-FTUs huggingface dataset:
White Paper : High-Resolution Micro-Ultrasound for Small Animal Cancer Imaging

3 Introduction . 3 Overview of Micro-Ultrasound Equipment Configuration, Imaging Set-Up And Data Quantification Capabilities . 5 What Can You Visualize With High-Resolution Micro-Ultrasound? 7 Tumor Sizing and Quantification in Twoand Three-Dimensions . 7 Evaluation and Quantification of Blood Flow . 8 Targeting Injections and Biopsies . 10 Contrast Agents for Performing Real-Time Tumor Perfusion and Targeted Molecular Imaging And Quantification of Biomarkers . 11 Detection and Quantification of Cardiocytotoxicity in Response to Anti-Cancer Therapy . 13 Expanding into Gene Delivery . 15 Conclusion . 15 References . 17
Evolution of plumage coloration and sexual dichromatism in the family Pittidae ( Passeriformes : Tyranni )

The role of different selective pressures underpinning plumage evolution has occupied biologists for the past century. However, only recently have scientists incorporated avian visual models into the study of plumage colors. Pittas are very colorful passerines and offer a great opportunity to investigate the mechanisms behind plumage diversification and intensity in sexual dichomatism. We used a tetrahedral color space model to quantify plumage coloration and a color distance model to access the degree of sexual dichromatism in this family. We tested whether plumage metrics are influenced by ecological variables using Ornstein-Uhlenbeck models with different selective regimes. We also performed an ancestral reconstruction analysis to investigate the evolution of sexual dichromatism in the family. We found that plumage diversity in this group is better explained under a Brownian motion model but that migratory behavior has affected plumage evolution in the genus Pitta. Sexual dichromatism is the plesimorphic condition in pittas and more wider spread than previously reported. Ultra violet reflectance is more pronounced in males of sexually dichromatic species, although conspicuity has increased in both sexes. These findings suggest that reciprocal sexual selection has likely taken place in this group, and that evolution of plumage colors in pittas is complex and has involved more than one evolutionary mechanism.
MICROSTRUCTURAL AND ELASTIC PROPERTIES OF SHORT FIBER REINFORCED COMPOSITES

The main contribution of this work is the prediction of the linear elastic properties of short fiber-reinforced composites (SFRCs) and the estimation of the fiber orientation distribution function (FODF) based only on fiber orientation tensors of second order. A SFRC consisting of polypropylene with 30wt% of short glass fibers is considered exemplary. In the first part, two micromechanically based mean field methods are applied to approximate the linear elastic properties of the composite. Both presented methods, the self-consistence method and a twostep bounding approach, are able to consider segmented microstructure date from, e.g., micro computer tomography measurements. In the second part, it is shown, how the FODF can be estimated without closure approximations using the maximum entropy method (MEM). 1. Homogenization of short fiber-reinforced composites 1.
Presentation : JoCaml , a Language for Concurrent Distributed and Mobile Programming

As traditional programming languages are designed for closed, sequential architectures, concurrent and distributed programming is either hard to achieve or error-prone. JoCaml as a high-level language was designed with dedicated support for concurrency, synchronization as well as the support for distributed execution of programs. JoCaml itself is based on the Join Calculus and extends the OCaml language, keeping all of it’s features. This written presentation will show how JoCaml can be used to achieve concurrent and distributed programming, with the main focus on concurrency.
Application of UV Imaging in Formulation Development

Efficient drug delivery is dependent on the drug substance dissolving in the body fluids, being released from dosage forms and transported to the site of action. A fundamental understanding of the interplay between the physicochemical properties of the active compound and pharmaceutical excipients defining formulation behavior after exposure to the aqueous environments and pharmaceutical performance is critical in pharmaceutical development, manufacturing and quality control of drugs. UV imaging has been explored as a tool for qualitative and quantitative characterization of drug dissolution and release with the characteristic feature of providing real-time visualization of the solution phase drug transport in the vicinity of the formulation. Events occurring during drug dissolution and release, such as polymer swelling,
Controllable Variable Line Size Cache Exploiting High On ‐ Chip Memory Bandwidth for Low Power Embedded SoCs

This paper proposes a software-controllable variable line-size (SC-VLS) cache architecture for low power embedded systems. High bandwidth between logic and a DRAM is realized by means of advanced integrated technology. In the merged logic/DRAM SoCs, it is important to reduce the DRAM energy consumption. The specific DRAM needs a small cache memory to improve the performance. We exploit the cache to reduce the DRAM energy consumption. The SC-VLS cache is able to change a line size to an adequate one at runtime with a small area and power overheads. We analyze the adequate line size and insert line size change instructions at the beginning of each function of a target program before executing the program. In our evaluation, it is observed that the SC-VLS cache reduces the DRAM energy consumption up to 50%, compared to a conventional cache with fixed 256B lines.
Perception of Logo and Brand Personalities

This research focuses on the respondents’ point of view to the brand and logo personalities. The Japanese version of Brand Personality Scale was used to measure the brand and logo personalities across five core dimensions: Excitement, Competence, Peacefulness, Sincerity and Sophistication. The research gave some insights into how company logos corresponded to the brand images. In addition, the Brand Personality Scale as a method of evaluation of the current status of brand and logo personalities was examined in case studies of Japanese companies. The result of these case studies showed that respondents perceived brand personality and logo personality in different way. The final investigation of all respondents’ answers indicated which personality factors have represented the significant differences in perception of brands and logos. These findings can provide a better understanding of personality factors that need more attention before a company decides to change its logo. The initial understanding of brand personalities and relationship with logos could help designers to extend the options of creativity and increase the possibilities for a logo to convey a variety of memorable messages, strong emotions and rich personalities.
The Value of Contrast-Enhanced Ultrasound Classification in Diagnosis of Pancreatic Cystic Lesions

Objective To compare the consistency of contrast-enhanced ultrasound (CEUS) classification results with magnetic resonance imaging (MRI) and to investigate the diagnostic value of CEUS classification in pancreatic cystic lesions. Methods 84 cases of pancreatic cystic lesions were enrolled in this study. According to the CEUS classification methods of previous study in our center, all the lesions were classified into four types: type I, unilocular cysts; type II, microcystic lesions; type III, macrocystic lesions; and type IV, cystic lesions with enhanced solid components. The consistency of CEUS and MRI typing results was analysed. Among the 84 cases, 45 cases had pathological results. The CEUS results were compared with the pathological results, and the diagnostic value of CEUS classification in diagnosing pancreatic cystic lesions was explored. Results Among the 84 cases, CEUS diagnosed 8 cases of type I, 24 of type II, 8 of type III, and 45 of type IV. MRI diagnosed 10 cases of type I, 25 of type II, 7 of type III, and 43 of type IV. The classification typing results of CEUS were highly consistent with that of enhanced MRI (kappa value: 0.852). Among the 45 cases with pathological results, the diagnostic accuracy of each type was 91.1%, 95.6%, 93.3%, and 88.9%. The accuracy of CEUS and MRI in diagnosing pancreatic cystic lesions was 75.56% (34/45) and 80% (36/45), respectively. The diagnostic accuracy of CEUS had no significant difference from that of MRI (P=0.687). Conclusion The classification results by CEUS and MRI are in excellent agreement. The classification of pancreatic cystic lesions by CEUS is significantly helpful for clinical diagnosis.
A influência do laboratório no tratamento da ceratite infecciosa

OBJETIVO: Avaliar a resposta terapeutica das ceratites infecciosas e sua correlacao com o resultado laboratorial. METODOS: Foram estudados 62 casos retrospectivamente de ceratite infecciosa de moderada a grave, atendidos no Hospitaldo Servidor Publico Estadual de Sao Paulo no periodo de janeiro de 2000 a dezembro de 2006. Foi avaliada a resposta ao tratamento topico com colirios antibioticos (Cefalotina 50mg/ml e Gentamicina 14mg/ml ou Ciprofloxacino 0,3%), verificando-se a necessidade de modificacao da terapeutica inicial de acordo com a evolucao clinica e correlacao com os testes microbiologicos pre-tratamento. RESULTADOS: Observou-se que 21 culturas (33,9%) foram positivas e 41 (66,1%) foram negativas. Houve crescimento de fungo em uma amostra (1,6%). Em apenas dois casos (3,5%) houve correlacao do exame bacterioscopico com o da cultura. Em 5 casos (8,1%) houve necessidade de modificacao da medicacao devido a piora clinica e 91,9% dos pacientes cursaram com cura do processo infeccioso com o tratamento inicial instituido. CONCLUSAO: O uso topico de antibioticos fortificados ou quinolonas foi eficaz no tratamento das ceratites de provavel etiologia infecciosa com culturas positivas e negativas.
A HOLISTIC APPROACH TO ARCHITECTURE AND ITS IMPLEMENTATION IN THE PHYSICAL AND CULTURAL CONTEXT OF THE PLACE

My on going search for what is behind the order of human environment, had been developed gradually by me since my studies at the Architectural Association (A.A) school of Architecture in London (Dip 1973), through research work with Prof. Christopher Alexander at the “Center for Environmental Structure” Berkeley California, my post graduate studies in Architecture & Buddhist studies at U.C. Berkeley (1979-81), and along my teachings and practice in Israel in the last 25 years.
Mass-Interaction Physical Models for Sound ans Multi-Sensory Creation : Starting Anew

Mass-interaction methods for sound synthesis, and more generally for digital artistic creation, have been studied and explored for over three decades, by a multitude of researchers and artists. However, for a number of reasons this research has remained rather conﬁdential, subsequently overlooked and often considered as the odd-one-out of physically-based synthesis methods, of which many have grown exponentially in popularity over the last ten years. In the context of a renewed research effort led by the authors on this topic, this paper aims to reposition mass-interaction physical modelling in the contemporary ﬁelds of Sound and Music Computing and Digital Arts: what are the core concepts? The end goals? And more importantly, which relevant perspectives can be foreseen in this current day and age? Backed by recent developments and experimental results, including 3D mass-interaction modelling and emerging non-linear effects, this proposed reﬂection casts a ﬁrst canvas for an active, and resolutely outreaching, research on mass-interaction physical modelling for the arts.
miR-222 induces apoptosis in human intervertebral disc nucleus pulposus cells by targeting Bcl-2

Intervertebral disc degeneration (IDD) is characterized by abnormal induction of apoptosis in intervertebral disc nucleus pulposus (NP) cells. Previous studies indicated that miR-222 was upregulated in patients with rheumatoid arthritis. However, the effects of miR-222 in IDD remain unclear. The present study aimed to demonstrate the role of miR-222 in NP cells. The levels of miR-222 in patients with IDD were measured by reverse transcription-quantitative PCR. Cell Counting Kit-8 and western blotting assays were used to detect cell proliferation and apoptosis-associated protein levels, respectively. In addition, luciferase reporter assays were performed to validate the predicted target genes of miR-222. miR-222 was significantly upregulated in patients with IDD. Overexpression of miR-222 inhibited cell proliferation and induced cell apoptosis. Moreover, overexpression of miR-222 resulted in an upregulation in the levels of Bax and cleaved caspase 3, and a downregulation in the levels of Bcl-2 in NP cells. The luciferase reporter assays demonstrated that Bcl-2 is a target of miR-222. Furthermore, overexpression of miR-222 increased the levels of cytochrome c, apoptotic protease activating factor-1 and cleaved caspase 9 in NP cells. Conversely, downregulation of miR-222 could promote the proliferation of NP cells. The present data demonstrated that miR-222 induced apoptosis in NP cells by directly targeting Bcl-2. Therefore, miR-222 may act as a potential therapeutic target for the treatment of IDD.
Application Research Based on 5G Wireless Communication Technology

Abstract With the continuous development of science and technology, network technology is changing from each passing day. Nowadays, smart phones and other products are gradually popularized. China’s mobile network technology is also developing rapidly. The development of communication technology has driven the development of society. Nowadays, the development of 5G wireless communication technology has greatly promoted the research of related technologies. With the advancement of the times, the number of people surfing the Internet has also increased greatly. China’s wireless communication technology will be greatly developed, and its application prospects are very broad, which has laid a great foundation for future scientific research and played a certain role. This paper further studies through the research of the core technology of 5G wireless communication technology. The core technologies of 5G wireless communication technology mainly includes wireless transmission and network architecture technology, Non-orthogonal multiple access technology, D2D communication networking, MIMO antenna technology, simultaneous co-frequency full-duplex technology, intelligent technology. With the advancement of time, 5G technology will be commercialized after 2020, which will meet the rapid development of mobile Internet services in the future and bring new experiences of users. As the research progresses, the key technologies of 5G will gradually become clear, and will enter the stage of standardization research and formulation in the next few years. 5G communication technology is the most advanced mobile communication technology. Compared with 4G communication technology, it is more than ten times faster than its data transmission speed, and has a significant advantage in fast transmission rate. From the practical application of 5G communication technology, the transmission speed can be guaranteed in the case of 28 GHz band 1Gbpses, and the transmission speed of 4G communication technology under the same conditions can only reach about 73Mbps, and the asymmetric data transmission capability is only higher than 3Mb/s. It can be seen that 5G communication technology achieves a significant increase in transmission speed.
Wound healing around dental implants

Dental implants have become a part of routine dentistry. Bone healing around modern implants follows established sequence of events and results in predictable osseointegration. Bone formation can be seen as early as four days after implant placement. In a healing bone wound, fibroblast-like osteogenic progenitor cells differentiate into osteoblasts and start to deposit woven bone that gradually grows towards the implant surface. During 1–3 months of healing, this woven bone is replaced by lamellar bone with increasing bone to implant contact that allows functional loading of the implant. As a clinical application, RFA has suggested that implant stability is initially decreased up to three weeks due to bone remodeling and followed by an increase to the baseline at 4–5 weeks and then reaching plateau in 8 weeks. Regardless of this remodeling, studies have shown that implants can be successfully loaded immediately after placement although with somewhat reduced survival rates. Development of new implant surfaces has played a critical role in expanding these clinical loading protocols. Soft tissue healing around implants has become a focus of attention because it plays a central role in esthetic outcomes. Healing of the peri-implant soft tissue occurs similarly to that against of a tooth after surgical procedure. Fibrin clot serves as a provisional matrix allowing epithelial and fibroblast migration towards the implant surface. Epithelial and connective tissue contact to the implant or abutment surface is established within 1–2 weeks and further maturation follows up to at least 12 weeks. In the established interphase, the peri-implant epithelium is similar but longer than the junctional epithelium against the tooth. Orientation of collagen fiber bundles also differs from natural tooth. Instead of attaching to the neck of the implant, collagen fibers run parallel and circumferentially around the implant. Future studies are needed to develop better implant designs and surfaces that improve the soft tissue healing for more predictable esthetical outcomes.
Zebrafish models of heart development and cardiovascular diseases

During the past two decades, the zebrafish (Danio rerio) has become a popular vertebrate model due to the number of large-scale mutagenesis screens that have been conducted successfully with this animal [1]. Compared with other mammalian models, such as those involving mice, the zebrafish offers several advantages, which are summarized in table 1 [2]. Almost the entire genome of the zebrafish is sequenced, and its gene functions are highly conserved compared with humans. The zebrafish organogenesis and related diseases because of its economic frugality, embryonic transparency, exuteral development, high fecundity and usefulness in large-scale genetic screens [3]. The advantages offered by the zebrafish make this teleost an appealing animal model in biology. The zebrafish recently became a subject of interest to various scientific communities. As a low vertebrate animal, the zebrafish has been used as a developmental and embryological model dating back to the 1930’s [4]. Although zebrafish cardiomyocytes are phenotypically immature, the stages of zebrafish heart development, as well as its fundamental heart functions, are very similar to those of other organisms, including the differentiation of myocardial and endocardial progenitors, the migration of these progenitors to the midline of the embryo, the formation of a linear heart tube, heart chambers and cardiac valves, the looping of the heart tube, and the development of the cardiac conduction system [5]. Fundamental heart functions are also similar between the zebrafish and humans [6]. Therefore, further studies Abstract
Staff experience of sound environment in operating rooms built with non-absorbing modules

Modular solutions for operation rooms made of glass and metal adversely affect the sound environment as the absorption of sound is non-existent. The requirement for Reverberation Time (T20) in operating rooms is according to Swedish Standard 25268 < 0.6 seconds. Modules without additional acoustic supplement are calculated to around 2.0 seconds. In our research the modular ceiling was replaced with an Absorption Class A ceiling according to ISO 11654. Both normal sized rooms (65m2) and the Hybrid room (105 m2) were treated with absorbents. To gain better understanding on the sound environment we also measured Speech Clarity (C50) in addition to reverberation time. All acoustic requirements were fulfilled and this paper aim to evaluate how the staff perceives the sound environment in these rooms. Information will be obtained by questionnaires sent to 78 staff at Sundsvall hospital. The hospital performs 11000 procedures a year in 15 operating rooms. Procedures contains of common surgical, gynecological and orthopedic operations, as well as hernias, cancer, ear-nose-throat and fractures. Operating times varies from short to long and staff alternates within all procedures, the unit is open during evening and night for emergencies. Questionnaire consists of both multiple-choice and open questions.
Characterization of turbulence noise in breathy human phonation

Breathiness is a voice quality type that may be a sign of a voice disorder. It involves the auditory perception of additive noise caused by turbulent trans-glottal airflow. Ten normal and ten breathy phonations recorded during high-speed videolaryngoscopy are analyzed. A method for extracting additive noise from audio recordings in the presence of modulation noise is presented. It generates quasi-unit pulse trains at a rate equal to the vocal frequency. The cycle shape is obtained by cross-correlating the pulse train with the audio signal. The cycle shape is then Fourier transformed and input to a Fourier synthesizer. Other inputs are the estimates of the instantaneous phase and the amplitude modulation function. The timing and height of the pulses are modulated so as to minimize the modeling error, which is the difference between the recorded audio signal and the output of the synthesizer. The error is assumed to approximate the additive noise in the voice. Differences of energy levels and spectral slope with respect to voice quality (breathy/normal) are reported. No differences with regard to cycle phase (open/quasi-closed) are reported.
Building deliberative places and spaces : Making sense of the power of food movements in governance processes in the Global North

Dominant food systems, based on industrial methods and corporate control, are in a state of flux. To enable the transition towards more sustainable and just food systems, food movements are claiming new roles in governance. These movements, and the initiatives they spearhead, are associated with a range of labels (e.g., food sovereignty, food security, and right to food) and use a variety of strategies to seek change. In this paper, we consider research exploring food movement actors’ efforts to put forth a framework for conceptualizing their roles in governance. We present our framework in the form of a continuum that conceptualizes governance engagement spanning from multi-stakeholderism to self-governance, with the key elements of orientation and framing, use of power, and political economic contexts shaping food movement actors’ positions on the continuum. Applying this framework to nine case studies, we offer three insights. First, power constellations can be initially “light” or “dense,” requiring different types of power on the part of food movements in order to engage. Second, we find that food movements use a distinct type of power, which we call the power to convene and create, enabling them to leverage other powers, prefigure the more inclusive policy making process they envisage, and increase the capacity of food movement actors. Third, using the power to convene may allow movement actors to reshape policy fields so they can seek longer-term governance arrangements that address the complexity of food systems. These insights challenge the traditional narrative of social movements as simply “inside” or “outside” by positioning food movements within shifting policy fields. Questions for feedback:  What are your impressions of our governance engagement continuum, including our conceptualizations of orientation, framing, power, and governance arrangements? Do you think it can be a helpful tool for researchers and social movement actors and