Miracle-dz/UniFAR-FTUs huggingface dataset:
ABC's and 123's: Parental Literacy, Numeracy, and Childhood Obesity.

In 2003, the National Assessment of Adult Literacy (NAAL) found that approximately 90 million Americans have basic or below basic literacy skills and that 110 million have basic or poor quantitative (numeracy) skills.1 Low literacy and numeracy skills are independently associated with poor understanding of health information, poor health behaviors, and poor clinical outcomes.2 In the context of nutrition and obesity, low health literacy/numeracy is associated with worse knowledge about breastfeeding, difficulty understanding food labels and portion sizes and higher body mass index (BMI) in adults.3–5 In 2003, Surgeon General Richard Carmona acknowledged that health literacy is a major problem in the United States, and recognized that low health literacy is likely “one of the largest contributors to our nation’s epidemic of overweight and obesity. ”6
Deep Learning for Logic Optimization

—The slowing down of Moore’s law and the emergence of new technologies puts an increasing pressure on the ﬁeld of EDA in general and the logic synthesis and optimization community in particular. There is a constant need to improve optimization heuristics. However, ﬁnding and implementing such heuristics is a difﬁcult task, especially with the novel logic primitives and potentially unconventional requirements of emerging technologies. In this paper, we show how logic optimization may be recast as a game. We then take advantage of recent advances in deep reinforcement learning to build a system that learns how to play this game. Our design has a number of desirable properties. It is autonomous because it learns automatically, and does not require handcrafted heuristics or other human intervention. It generalizes to large multi-output Boolean functions after training on small examples. Additionally, it natively supports both single-and multi-output functions, without the need to handle special cases. Finally, it is generic because the same algorithm can be used to achieve different optimization objectives, e.g., size and depth.
STUDI KOMPARATIF PEMBOBOTAN KRITERIA AUDIT KINERJA AUDITOR BADAN PEMERIKSA KEUANGAN DENGAN PEMBOBOTAN MENGGUNAKAN METODE ANALYTICAL HIERARCY PROCESS (STUDI KASUS PADA INSPEKTORAT KABUPATEN KEPULAUAN TALAUD)

This study aimed to recalculate the weighting of performance audit criteria by using Anlytical Hierarchy Process Method and comparing its results with the weighting of performance audit of Indonesian Supreme Audit Institution’s Auditor (BPK). Research conducted on Supervisory Apparatus Capability Model Government (APIP) at the Office of Inspectorate of Talaud Regency. This research is a descriptive qualitative-quantitative approach.Method of data collection with interviews, documentation and questionnaire. The results showed that in weighting of performance audit criteria, BPK’s auditor still use direct weighting and judgment, and there is a difference of percentage between performance audit criteria of BPK auditor and using AHP method. Keywords : Weighting, Performance Audit Criteria, AHP
Avian gut-associated lymphoid tissues and intestinal immune responses to Eimeria parasites

Coccidiosis, an intestinal infection caused by intracellular protozoan parasites belonging to several different species of Eimeria, seriously impairs the growth and feed utilization of livestock and poultry. Host immune responses to coccidial infection are complex. Animals infected with Eimeria spp. produce parasite-specific antibodies in both the circulation and mucosal secretions. However, it appears that antibody-mediated responses play a minor role in protection against coccidiosis. Furthermore, there is increasing evidence that cell-mediated immunity plays a major role in resistance to infection. T lymphocytes appear to respond to coccidial infection through both cytokine production and a direct cytotoxic attack on infected cells. The exact mechanisms by which T cells eliminate the parasites, however, remain unclear. Although limited information is available on the intestinal immune system of chickens, gut lymphoid tissues have evolved specialized features that reflect their role as the first line of defense at mucosal surfaces, including both immunoregulatory cells and effector cells. This review summarizes our current understanding of the avian intestinal immune system and mucosal immune responses to Eimeria spp. , providing an overview of the complex cellular and molecular events involved in intestinal immune responses to enteric pathogens.
Temperature Sensing System With Short-Range Wireless Sensor Based on Inductive Coupling

This paper presents the theory, development, and results for a temperature sensing system that employs a wireless sensor with powering and communications based on inductive coupling. The theory of inductive coupling is presented along with a methodology that has been developed to determine the system elements in order to fulfill communication range and bandwidth requirements in a certain class of applications. A miniaturized wireless sensor was built (volume 3.2 cm3), and the whole system was validated by means of an experiment where the sensor was immersed in a water bath, in which the temperature was varied during 69 h in a cycle covering a span of 30°C. Measurements had a high correlation with an accurate reference thermometer. It is shown that the interruption of the radio frequency (RF) field during the measurements is a useful method to improving the measurement quality. In the course of the validation experiment, this method reduced the standard deviation of the measures up 0.01°C.
Ubiquitous Sensing : Towards the future of IoT operating systems

Internet of Things (IoT) is projected to connect billions of devices as they get smaller and cheaper. IoT devices range from low-end units to devices having powerful processors. Traditional operating systems are not able to fulfil the diverse requirements of heterogeneous IoT devices. The requirements of an OS for IoT devices need to be revisited to operate with minimal resources and at the same time cover a wide range of devices, thereby avoiding redundant development, and maintenance of devices. This paper presents an analysis on such requirements and a comparative study of some current IoT operating systems.
How I treat How I treat idiopathic thrombocytopenic purpura (ITP)

Our goal is to set forth our opinion of the best approach to managing adults with primary idiopathic (autoimmune) thrombocytopenic purpura (ITP), with emphasis on the word “opinion. ” The paucity of evidence-based medicine on this topic has been noted.1 Both the American Society of Hematology2 and the British Committee for Standards in Haematology General Haematology Task Force3 have issued “practice guidelines. ” These, in large part, proved to be compendia of opinions from panels of experienced physicians who concurred on some matters but not on others. We cite published evidence where we find it compelling and reproducible, but much of what follows rests on our mutual experience treating patients, both onand off-study, rather than an encyclopedic, heavily referenced review. Many issues remain unresolved, expert opinions differ for good reason, and it is likely that our own approach will change based on emerging data. Comprehensive reviews on pathogenesis, laboratory testing, secondary ITP, ITP in children, and treatment are to be found elsewhere.4,5
Formant Interaction as a Cue to Vowel Perception: A Case Report

Accumulating evidence indicates that cerebral processing of consonants and vowels is separable. It has been shown that disordered temporal acuity leads to disturbed consonant perception in cases with pure word deafness. In contrast, there has been no clear explanation of how vowel perception is impaired. We examined a patient with auditory agnosia, who showed a differential ability to identify the five Japanese vowels after bilateral cerebral lesions. He correctly identified the vowel [a] in more than 70% of auditory presentations, whereas he identified [i] in only about 30% of presentations. The difference between the first and second formant frequencies “F2–F1” and an artificially defined value “F1–(F2–F1)” for each vowel correlated significantly with the percentage of correct identifications. These findings support the hypothesis that vowel perception is based on formant interactions.
Factors affecting the reactivity of human lymphocytes in vitro. I. Cell number, duration of culture and surface area.

Quantitative studies of immunologically stimulated blood leukocytes in vitro show that DNA synthesis is affected by variations in cell number, duration of culture and area of the surface on which the cells are cultured. Of particular interest is the demonstration in both mixed leukocyte and antigen-stimulated cultures that as cell proximity increases the synthesis of DNA increases proportionally. It is suggested that this increase in DNA synthesis is the result of recruitment of otherwise nonreactive lymphocytes through the previously demonstrated mechanism of uropodapsis.
Motion alterations after anterior cruciate ligament reconstruction: comparison of the injured and uninjured lower limbs during a single-legged jump.

CONTEXT Asymmetries subsist after anterior cruciate ligament reconstruction (ACL-R), and it is unclear how lower limb motion is altered in the context of a dynamic movement. OBJECTIVE To highlight the alterations observed in the injured limb (IL) during the performance of a dynamic movement after ACL-R. DESIGN Cross-sectional study. SETTING Research laboratory. PATIENTS OR OTHER PARTICIPANTS A total of 11 men (age = 23.3 ± 3.8 years, mass = 81.2 ± 17.0 kg) who underwent ACL-R took part in this study 7.3 ± 1.1 months (range = 6-9 months) after surgery. INTERVENTION(S) Kinematic and kinetic analyses of a single-legged squat jump were performed. The uninjured leg (UL) was used as the control variable. MAIN OUTCOME MEASURE(S) Kinematic and kinetic variables. RESULTS Jump height was 24% less for the IL than the UL (F1,9 = 23.3, P = .001), whereas the push-off phase duration was similar for both lower limbs (P = .96). Knee-joint extension (F₁,₉ = 11.4, P = .009), and ankle plantar flexion (F₁,₉ = 22.6, P = .001) were less at takeoff for the IL than the UL. The hip angle at takeoff was not different between lower limbs (P = .09). We found that total moment was 14% less (F₁,₉ = 11.1, P = .01) and total power was 35% less (F₁,₉ = 24.2, P = .001) for the IL than the UL. Maximal hip (P = .09) and knee (P = .21) power was not different between legs. The IL had 34% less maximal ankle power (F₁,₉ = 11.3, P = .009) and 31% less angular velocity of ankle plantar flexion (F₁,₉ = 17.8, P = .004) than the UL. CONCLUSIONS At 7.3 months after ACL-R, motion alterations were present in the IL, leading to a decrease in dynamic movement performance. Enhancing the tools for assessing articular and muscular variables during a multijoint movement would help to individualize rehabilitation protocols after ACL-R.
Runge-Kutta Discontinuous Galerkin Method Using WENO Limiters

The Runge--Kutta discontinuous Galerkin (RKDG) method is a high order finite element method for solving hyperbolic conservation laws. It uses ideas from high resolution finite volume schemes, such as the exact or approximate Riemann solvers, total variation diminishing (TVD) Runge--Kutta time discretizations, and limiters. It has the advantage of flexibility in handling complicated geometry, h-p adaptivity, and efficiency of parallel implementation, and has been used successfully in many applications. However, the limiters used to control spurious oscillations in the presence of strong shocks are less robust than the strategies of essentially nonoscillatory (ENO) and weighted ENO (WENO) finite volume and finite difference methods. In this paper we investigate using WENO finite volume methodology as limiters for RKDG methods, with the goal of obtaining a robust and high order limiting procedure to simultaneously obtain uniform high order accuracy and sharp, nonoscillatory shock transition for RKDG methods.
Distributed network control for establishing reliability-constrained least-cost lightpaths in WDM mesh networks

A control scheme which is used to set up and tear down lightpaths, should not only be fast and efficient, must also be scalable, and should try to minimize the number of blocked connections; while satisfying the requested level of fault-tolerance. In this work we propose a distributed control scheme based on preferred link approach for establishing reliability-constrained least-cost lightpaths, by choosing the reliability of a lightpath to denote the level of fault-tolerance required by the connection request. Four heuristics are proposed and their performance is studied through extensive simulation experiments. The simulation results suggest that our heuristics provide better performance compared to other distributed protocols available, in terms of average call acceptance rate, average path cost, average routing distance, and average connection setup time; when the connection requests with different levels of fault-tolerance requirements arrive to and depart from the network randomly.
Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status

Alterations of the TP53 tumor suppressor gene occur in ~30% of primary glioblastoma (GBM) with a high frequency of missense mutations associated with the acquisition of oncogenic “gain-of-function” (GOF) mutant (mut)p53 activities. PRIMA-1MET/APR-246, emerged as a promising compound to rescue wild-type (wt)p53 function in different cancer types. Previous studies suggested the role of wtp53 in the negative regulation of the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT), a major determinant in resistance to therapy in GBM treatment. The potential role of MGMT in expression of p53 and the efficacy of PRIMA-1MET with respect to TP53 status and expression of MGMT in GBM remain unknown. We investigated response to PRIMA-1MET of wtp53/MGMT-negative (U87MG, A172), mutp53/MGMT-positive U138, LN-18, T98/Empty vector (T98/EV) and its isogenic MGMT/shRNA gene knockdown counterpart (T98/shRNA). We show that MGMT silencing decreased expression of mutp53/GOF in T98/shRNA. PRIMA-1MET further cleared T98/shRNA cells of mutp53, decreased proliferation and clonogenic potential, abrogated the G2 checkpoint control, increased susceptibility to apoptotic cell death, expression of GADD45A and sustained expression of phosphorylated Erk1/2. PRIMA-1MET increased expression of p21 protein in U87MG and A172 and promoted senescence in U87MG cell line. Importantly, PRIMA-1MET decreased relative cell numbers, disrupted the structure of neurospheres of patient-derived GBM stem cells (GSCs) and enabled activation of wtp53 with decreased expression of MGMT in MGMT-positive GSCs or decreased expression of mutp53. Our findings highlight the cell-context dependent effects of PRIMA-1MET irrespective of p53 status and suggest the role of MGMT as a potential molecular target of PRIMA-1MET in MGMT-positive GSCs.
User-generated content on the Facebook page of an emergency management agency: A thematic analysis

Purpose The purpose of this study is to explore themes eventuating from the user-generated content posted by users on the Facebook page of an emergency management agency. Design/methodology/approach An information classification framework was used to classify user-generated content posted by users including all of the content posted during a six month period (January to June, 2015). The posts were read and analysed thematically to determine the overarching themes evident across the entire collection of user posts. Findings The results of the analysis demonstrate that the key themes that eventuate from the user-generated content posted are “Self-preparedness”, “Emergency signalling solutions”, “Unsurpassable companion”, “Aftermath of an emergency”, and “Gratitude towards emergency management staff”. Major user-generated content identified among these themes are status-update, criticism, recommendation, and request. Research limitations/implications This study contributes to theory on the development of key.
Methoxychlor‐induced alteration in the levels of HSP70 and clusterin is accompanied with oxidative stress in adult rat testis

Methoxychlor, an organochlorine pesticide, has been reported to induce abnormalities in male reproductive tract. However, the insight into the mechanisms of gonadal toxicity induced by methoxychlor is not well known. We investigated whether treatment with methoxychlor would alter the levels of stress proteins, heat shock proteins (HSP), and clusterin (CLU), and oxidative stress‐related parameters in the testis of adult male rats. Animals were exposed to a single dose of methoxychlor (50 mg/kg body weight) orally and were terminated at various time points (0, 3, 6, 12, 24, and 72 h) using anesthetic ether. The levels of HSP70, CLU, and the activities of superoxide dismutase (SOD), catalase, and lipid peroxidation levels were evaluated in a 10% testis homogenate. A sequential reduction in the activities of catalase and SOD with concomitant increase in the levels of thiobarbituric acid reactive substance (TBARS) was observed. These changes elicited by methoxychlor were very significant between 6–12 h of posttreatment. Immunoblot analysis of HSP revealed the expression of HSP72, an inducible form of HSP, at certain time points (3–24 h) following exposure to methoxychlor. Similarly, the levels of secretory CLU (sCLU) were also found to be elevated between 3–24 h of treatment. The present data demonstrate methoxychlor‐elicited increase in the levels of inducible HSP72 and sCLU, which could be a part of protective mechanism mounted to reduce cellular oxidative damage. © 2009 Wiley Periodicals, Inc. J Biochem Mol Toxicol 23:29–35, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jbt.20262
Videogame industry overview (panel session): technology, markets, content, future

Description While innovative (but secretive) early on, the videogame industry is now rejoining the computer graphics mainstream. In production, we see a rapid move from 2D to 3D animation, lowend to high-end production technologies, limited in-house tools to cutting-edge animation production techniques such as motion capture and 3D character animation. In game formats, we see experimentation with multi-player games, cooperative strategies, and virtual reality. Interactive entertainment overall is a rapidly expanding area with a great requirement for creative intervention and sophisticated computer graphics. The videogame industry has only very recently come into focus for many people in the computer graphics field, yet this industry is now driving much of the technology development in computer animation. Videogame development is being drawn deeper into the media mainstream. We have entered the age of the "commercial transmedia supersystem" where entertainment content is proliferated across multiple marketing opportunities: the game, the movie, the music CD, the book, the doll. Application developers have recently focused on an "author once, deploy many" imperative for cost effective production. As a new generation tackles the problem of interactive content production, their tools apply contemporary technical solutions to a process done with graph paper and assembler code not so many years ago. Videogame content may evolve as well, driven by the new delivery systems which underly market growth. For example, the corporate dreams of interactive television list the two largest consumer revenue areas as shopping and (then) games. Ubiquitous interactive television would certainly leverage today's limited multi-user games. New audiences means designing for new cognitive models of fun and taking advantage of recent research in how media products relate to gender and childhood development. Electronic gaming could evolve to encompass nationwide social events such as elections, celebrity trials, virtual participation in natural disasters, and so forth. All these new products, applications, and markets require technical, design, and artistic contributions for development, yet our skills, knowledge sets, and innovation must be translated into the new forms. To make this translation we must develop a coherent picture of how this industry is currently constituted and how it may evolve in the future. This panel will focus on a number of topics including platform hardware, delivery systems and their markets, the move into 3D computer graphics, virtuality in videogame design, overlapping areas of interactive entertainment, e.g. multimedia and theme parks, markets and content, and projected future developments.
The Cryptocurrency Tumblers: Risks, Legality and Oversight

Services known as Cryptocurrency “Tumblers” obfuscate the provenance, possession, and movement of cryptocurrencies through a process of “mixing” . While this speaks to the cryptoanarchist philosophical roots of cryptocurrencies, it poses various forms of risks, particularly those subsumed by the anti-money laundering (AML) category. This discussion paper examines that dichotomy, between cryptoanarchism and oversight, through the Tumbler lens, so as to consider the regulation, oversight, and legality of Tumblers themselves.
A New Perspective on the Benefits of Slack Building Under Participative Budgeting

In contrast to authoritative budgeting, participative budgeting may improve the superior's knowledge and increase the subordinate's motivation, but often comes at the costs of padding budgets and slack building. Consequently, most analytical studies identify slack as one of the major costs of participative budgeting that signifcantly reduce its benefits. Despite these research findings, participative budgeting is widely used in corporate practice. In this paper, we identify a beneficial effect of participative budgeting that has been neglected so far in analytical accounting research. In particular, we argue that slack might have benefits for the firm if the impact of participative budgeting on the firm's supply side is taken into account. We employ a tractable adverse selection model to capture the interactions between budgetary slack and decisions made inside the firm with the firm's choice of production quantity and the supplier's input price decision. We demonstrate that slack building induces an increase in the costs of production, but at the same time might soften supplier pricing. Overall, the interplay between frictions within the firm that are due to agency problems and the supplier's pricing response crucially affect the firm's choice of participative budgeting over authoritative budgeting. The main insight of our paper is that an exclusive focus on intra-firm aspects of budgeting might miss important effects of participative budgeting. It seems fruitful to consider the interaction between external stakeholders and a firm's budgeting approach in future empirical research.