Miracle-dz/UniFAR-FTUs huggingface dataset:
EFICIÊNCIA DE REMOÇÃO IN SITU DE BTEX POR POA FENTON EM FUNÇÃO DE VARIÁVEIS DO MEIO E OPERACIONAIS

Benzeno, Tolueno, Etilbenzeno e Xileno (BTEX) sao hidrocarbonetos aromaticos presentes na gasolina e possuem caracteristicas toxicas, nao biodegradaveis, sendo os principais responsaveis pela gravidade da contaminacao da gasolina no meio ambiente. O enfoque deste estudo foi a remediacao in situ de aguas subterrâneas contaminadas por BTEX por meio do Processo Oxidativo Avancado (POA) Fenton. O objetivo foi subsidiar um melhor planejamento desse tipo de intervencao utilizando os metodos de injecao Direct Push, Pressao em poco e Gravidade em poco. Para isso, foram caracterizados e interpretados os resultados da eficiencia de remocao (ER) de BTEX obtidos em quatro areas. Por meio de analises de regressao multipla, foram geradas relacoes matematicas para descrever o efeito das variaveis do meio e das condicoes de aplicacao sobre a ER de Benzeno, as quais poderao ser utilizadas no planejamento de remediacoes futuras.
Organoids as a Form of Modern Day Silver Lining

Blood Cancer-in the shape of carcinogenesis, is worldwide recognized, as a recent time catastrophe. Its unique capability of sustaining its dormancy, vulnerabilities, of drug screening methodologies, and most importantly therapeutic resistance of tumour affected stem cells(due to the redundancy of CD-133+ cells against Radio therapeutic treatment procedure and existence of MDR1, and ALDH-1 proteins in drug screening methodologies) [1] has transformed blood cancer, as hardly curable. To face this challenge; Organoids are figured out to be a possible solution. From a researcher’s point of view organoids are generally 3D structured in (vivo) clusters of stem cell molecules [2], showcasing bio-active capabilities. However, the lower success rate of organoids, bespeaking its initial stages of preclinical level of studies. In addition, most of these models & their implications just only been limited to in (vivo) principles and various forms of cancer exemplifying; Blood lymphoma. Interestingly, some recent milestones of organoids in different research models on metastasis reflect the glimpses of hopes. At this present study, we have worked on organoids and their possible involvement in blood cancer. We have emphasized on organoid modelling both in (vivo) and in (vitro) cell culture, which are some excellent sources for cell analysis. Presently, we have established a model where a Nano-sized in (vitro-vivo) cell clustering of organoids with an MRI scanning technique been utilized to build a more precise and useful therapeutic tool. This innovative approach would help us to identify the tumours that will not respond to any conventional therapies. Also in our studies the organoids have shown active cellular level of immunomodulation, leading to a proper signal transduction. As a consequences, this revolutionary model creates opportunities for a better outcome in terms of diagnostics and therapeutics. Original Research Article Kadir; IRJO, 2(2): 1-17, 2019; Article no.IRJO. 50404 2
Assessment of radiological parameters of river water and sediment in some oil producing communities of delta state of Nigeria

Abstract Gamma ray spectra of natural radioactivity from 238U, 232Th, and 40K in sediments and water samples from rivers in eleven oil-producing and two non-oil producing communities in Delta state of Nigeria have been evaluated using gamma-ray spectrometer with the hyper-pure germanium detector. Measured activity concentrations in water samples ranged from 1.17 Bq L−1 to 14.65 Bq L−1 for 40K; 0.26 Bq L−1 to 3.11 Bq L−1 for 232Th and 1.05 Bq L−1 to 5.58 Bq L−1 for 238U. The specific activity due to 232Th is found to be relatively low compared to that of 238U in all the water sample investigated. In the sediment samples, activities of 40K ranged from 32.47 Bq kg−1 to 525.1 Bq kg−1, 232Th ranged from 6.31 Bq kg−1 to 19.33 Bq kg−1 and values of 238U ranged from 4.45 Bq kg−1 to 18.69 Bq kg−1. The radiological hazard indices reported in this work include absorbed dose (D), radium equivalent dose (Req), external and internal hazard indices (Hex, Hin), annual effective dose equivalent (AEDE), lifetime average annual dose associated with water resources (LAAD), and excess lifetime cancer risk (ELCR). The values of the radiological hazard indices obtained were observed to be lower than limits internationally reported for both water and sediment, but observed concentration values at the oil-producing study areas are in most cases higher than values from the non-oil producing sites.
Novel One-Pot Synthesis of Methyl 4-Hydroxy-2-thioxo-1,2-dihydroquinoline-3-carboxylate: Synthetic and Crystallographic Studies

A new suitable method of synthesis of methyl 4-hydroxy-2-thioxo-1,2-dihydroquinoline-3-carboxylate by condensation of methyl 2-isothiocyanatobenzoate and methyl malonate is described. The structure of the compound both and by-product methyl 2(methoxycarbonothioylamino)benzoate was confirmed by means of elemental analysis, 1H NMR, 13C NMR, LC/MS and single crystal X-ray diffraction. UV/Vis and IR spectra of compounds are described. The presence of a strong intramolecular hydrogen bond between the hydroxy group and the carbonyl oxygen atom of the ester group in methyl 4-hydroxy-2-thioxo-1,2-dihydroquinoline-3-carboxylate is shown. The crystal structure of product was stabilized through intermolecular hydrogen bonds.
A Study on the Antioxidant and Antimicrobial Activities of Seed and Leaf Extracts of Glycine max (L) Merr.

The present study was carried out to evaluate the antioxidant and antimicrobial activities of ethanolic leaf and seed extracts of Soybean (Glycine max (L) Merr. ). Antioxidant activity of the leaf and seed extracts was determined by reducing power capacity of flavonoid, phenol, lycopene, βcarotene and ascorbic acid using standard laboratory method. The antimicrobial assay of the leaf and seed extracts was carried out at different concentrations against some selected clinical pathogens (bacterial strains: Staphylococcus aureus, Escherichia coli; fungi strain: Candida albicans, Aspergillus niger) using agar diffusion method. Analysis of variance was employed in data analysis. Antioxidant phytochemical composition of the leaf and seed extracts of Glycine max revealed that all the phytochemicals assayed were present but in various amounts except ascorbic acid that was absent in the leaf. The quantities of the phytochemicals were higher in the leaf than in the seed except for lycopene that was higher in the seed and ascorbic acid that was present only in the seed. The Reducing Power Capacity of the ethanol extract of the leaf and seed of the Glycine Original Research Article Igboabuchi and Ilodibia; AJRIB, 1(1): 1-8, 2018; Article no.AJRIB. 40123 2 max indicated that Glycine max extracts though had a reducing power capacity but is very low in comparison with the standard used. The effectiveness of the extracts increases slightly as the concentration increases. Antimicrobial studies indicated that the ethanolic leaf and seed extracts of Glycine max inhibited the growth of the investigated microbes and the inhibition was concentration dependent. The leaf extract showed higher inhibition than the seed. However, the ethanolic leaf and seed extracts showed no inhibition against bacterial strains at 50 mg/ml. Data obtained from the studies showed that the plant possessed antioxidant and antimicrobial properties and could be used in the treatment of microbial infections especially fungi infections and also to protect cells against free radical and excessive light damages. However, the leaf extract showed better inhibition than the seed extract indicating that it is a better antimicrobial agent than the seed.
Pneumonia and the Syndrome of Inappropriate Antidiuretic

including acute bronchospasm, intra­ thoracic infections, neoplastic process­ es, acute and chronic respiratory failure, and mechanical ventilation have all been associated with hyponatremia (4). While the pathophysiology of the hyponatre­ mia is not entirely clear, in virtually all studies where it has been measured, plas­ ma vasopressin is elevated. This nonos­ motic release of vasopressin then impairs renal water excretion and in the presence of excessive water intake leads to hypo­ natremia. The mechanism(s) wherebypulmonary disorders lead to increased plasma vaso­ pressin concentration is not entirely known. In the absence of an osmotic stimulus, increased plasma vasopressin levels are generally caused by either nonosmotic stimulation of central vaso­ pressin release or ectopic vasopressin production (4). Alterations in vasopres­ sin metabolism and clearance in the pres­ ence of pulmonary disease have not been studied. Pulmonary disorders may stimu­ late central vasopressin release via sever­ al pathways (4). Both hypoxemia and hy­ percapnia have been shown to elevate plasma vasopressin levels presumably by stimulating either peripheral chemore­ ceptors or baroreceptors. Mechanical
Three New Spongian Diterpenes from the Marine Sponge Dendrilla rosea

Three new diterpenes, aplyroseols 20–22 (2–4), were isolated from two specimens of the Australian marine sponge Dendrilla rosea. The structures and relative configurations of the new metabolites were elucidated from analysis of 2D NMR data. The compounds were screened for activity against Staphylococcus aureus, but were inactive at 64µgmL−1.
Natural Draft-Improved Carbonization Retort System for Biocarbon Production from Prosopis juliflora Biomass

Charcoal is a carbon rich fuel produced predominantly from carbonization of wood with a limited amount of oxygen. In this study a natural draft improved charcoal retort system was developed, and the produced charcoal has been analysed and characterized. The optimal carbonization temperature of retort was established to be 500°C. At this temperature the mass yield of charcoal was about 29.6 wt%. The energy yield was about 51.8 % of the initial energy contained in the biomass. Fixed carbon content was about 78.1 %. Charcoal heating value was about 30.8 MJ/kg. The charcoal produced from Prosopis Juliflora can be used as a fuel for industrial heat production and in domestic cooking in rural areas. The retort system operates in an environmentally friendly way with very low emissions of CO, CO2, hydrocarbons and particulate matter.
Selective Oxidation of Methane to Methanol on Cu-Based Catalysts Supported on Microporous Materials

Formation of Cu trimers hosted in mordenite, which oxidize methane selectively into methanol, occurs via thermally driven mobilization of Cu+ species, followed by their facile oxidation. Reactivity of Cu-oxo clusters is affected by their location in the zeolite micropore structure and by interaction with adjacent extra-framework Al species. Therefore, control of both extra-framework Al formation and Cu speciation is critical for synthesizing active Cu-zeolites. Supports suitable to host active Cu-oxo clusters provide structural confines, well-defined pore structure and anchoring sites as well as thermal stability and oxidation resistance.
Gyrotropic slab waveguide coupled silica microfiber-based magnetic field sensor

Abstract Intensive transient magnetic field measurement is highly necessary in modern electric power systems. In this paper, a novel compact microfiber-based magnetic field sensor for real-time detection of intense magnetic field is presented. The sensor consists of a silica microfiber with an attached gyrotropic slab waveguide. By the exploration of the magnetic-optic Kerr effect of the gyrotropic slab, the variations of its refractive index under an external magnetic field leads to the coupling spectrum of the sensor shifting. Using this probe, static magnetic fields with strengths up to 2 T and square waveform signals with rise times of 5 ms were successfully measured.
(Bi0.2Sb0.8)2Te3 based dynamic synapses with programmable spatio-temporal dynamics

Neuromorphic computing has recently emerged as a promising paradigm to overcome the von-Neumann bottleneck and enable orders of magnitude improvement in bandwidth and energy efficiency. However, existing complementary metal-oxide-semiconductor (CMOS) digital devices, the building block of our computing system, are fundamentally different from the analog synapses, the building block of the biological neural network—rendering the hardware implementation of the artificial neural networks (ANNs) not scalable in terms of area and power, with existing CMOS devices. In addition, the spatiotemporal dynamic, a crucial component for cognitive functions in the neural network, has been difficult to replicate with CMOS devices. Here, we present the first topological insulator (TI) based electrochemical synapse with programmable spatiotemporal dynamics, where long-term and short-term plasticity in the TI synapse are achieved through the charge transfer doping and ionic gating effects, respectively. We also demonstrate basic neuronal functions such as potentiation/depression and paired-pulse facilitation with high precision (>500 states per device), as well as a linear and symmetric weight update. We envision that the dynamic TI synapse, which shows promising scaling potential in terms of energy and speed, can lead to the hardware acceleration of truly neurorealistic ANNs with superior cognitive capabilities and excellent energy efficiency.
Formulation strategies for extracellular vesicle delivery

Stem cells therapies have been demonstrating their ability to elicit cell replacement in tissues where there has been a loss of function or damage. However, cell-secreted extracellular vesicles (EVs) have been shown to be responsible for much of these regenerative effects. In the scarred myocardium after an infarct, EVs have shown cardioprotective effects upon injection. However, administration via injection has severe limitations, since much of the administered dose is rapidly cleared from the site of action. Development of implantable EV formulations is then needed. EVs from foetal bovine serum and from mesenchymal stem cells culture media were isolated and characterised. A differential centrifugation workflow was assessed to identify a robust and reproducible isolation method. Both isolation and protein characterisation were found to be highly dependent on the starting material, indicating that a careful assessment is required for each sample. The effect of EVs on stressed cardiomyocytes in culture was assessed in vitro and found to be concentration dependent. FBS EVs were found to be relatively stable over the course of a month at the storage conditions of -80◦ C, 4◦ C and 20◦ C. The feasibility of formulating EVs into a scaffold by electrospinning was explored, initially using fast-dissolving polymers such as poly(vinyl pyrrolidone). Extensive optimisation of processing conditions was undertaken and no difference in pre and postprocessing EVs potency was noted in cell culture assays, confirming electrospinning to be suitable for EV formulation. Finally, development of sustained-release scaffolds for cardiac applications was investigated, based on poly(lactic-co-glycolic acid) and poly(dioxanone). A range of systems was prepared and morphology, flexibility, shrinkage behaviour and mechanical properties explored. However, scaffolds were found to have a burst release at 24 h with no more release detected over the 4 week period. Overall, the results obtained are encouraging and lay the formulation foundations for potential EV clinical applications.
Handoffs & Handovers: Collaborating in Turns

Handoffs and handovers are common in many domains. They are crucial to effective team performance, but are also considered ripe opportunities for the introduction of errors and inefficiencies. The workshop will examine the various types of handovers/handoffs, ways of better supporting handoffs/handovers with technology, and possible benefits of handovers/handoffs. It is expected that the workshop will help advance understanding of handoffs/handover as a form of collaboration and will bring relevant collaboration research to bear on the problem of errors in handoffs/handovers. Author Keywords Handoff, handover, collaboration, asynchronous, routines.
Iron Functionalized Zinc Peroxide nanomaterial for removal of Arsenic and Chromium from contaminated water

October December 2019 134 JCPS Volume 12 Issue 4 Iron Functionalized Zinc Peroxide nanomaterial for removal of Arsenic and Chromium from contaminated water Anita Gupta*, Rohit Babu Aniyery, Anjali Sharma, Nahar Singh, Bharti Sharma Amity Institute of Applied Sciences, AUUP, Noida (India). Department of Chemistry, Amity Institute of Applied Sciences (AIAS), Amity University, Noida-201301, Uttar Pradesh (India). Department of Analytical Chemistry, CSIR-National Physical Laboratory, Dr. K. S. Krishnan Marg, New Delhi-110 012, India Department of Chemistry, University of Delhi, New Delhi110021, India. *Corresponding author: E-Mail: agupta3@amity.edu, Contact Number: +91-9582158263 ABSTRACT In the present research work we have done some preliminary work related to water purification especially contaminated by arsenic and chromium. We have synthesized iron functionalized ZnO2 nanomaterials of varying sizes characterized the phase of iron functionalized ZnO2 nanomaterial by XRD, shape and particle size by SEM, TEM and particle size by Microtech particle analyser. It was further characterized by Dynamic Light Scattering (DLS) method in order to determine their average particle size and magnitude of the overall charge on the nanoparticles and have been used for expatriation of arsenic and chromium. The proposed nanomaterials are of low cost, non toxic and highly efficient in removing arsenic and chromium from drinking water. The proposed nanomaterials purify arsenic and chromium contaminated water up to the permissible range of drinking water. The arsenic and chromium removal efficiency of iron functionalized ZnO2 nanomaterial are taken at different time interval and pH range. It has been concluded from the observation that iron functionalized ZnO2 nanomaterial is more effective and removes arsenic and chromium, below detection limit of FAAS/ AAS-HG (Atomic absorption spectroscopy (AAS)). The purified water can be used for drinking purpose and other house hold utilities. We have made attempt for the appropriate removal of heavy metals (Arsenic and Chromium) from contaminated water below the prescribed limit of World Health Organization (WHO) and Environmental Protection Agency (EPA) by using low cost, iron functionalised zinc peroxide nanomaterial.
Detection of combination effect of silver nanoparticles prepared with Pimpinella anisum and some antibiotics on some pathogenic bacteria

This article aims to detect the effect of combining silver nanoparticles prepared with the extract of the Pimpinella anisum seeds and was obtained from the local markets in the city of Kirkuk. Iraq with some antibiotics on antibiotic resistance bacteria (E.coli and Staphylococcus aureus ) were obtained from Kirkuk General Hospital and re-diagnosed based on reliable diagnostic sources. This study demonstrates that the P. anisum seeds extract reduced the silver ion through changing the solution color to reddish brown. The examination of silver nanoparticles synthesized by P. anisum the extract of seeds was carried out using X-ray and SEM (Scanning electron microscopy) and X-ray showed spherical shape particles with 44 nm in size with three diffractions which are indexed as (111), (200) and (220)and the SEM images showed clear particales. The synergistic effects of biosynthesis AgNPs at different concentrations with different standard antibiotic discs (Amoxicillin, chloramphenicol, Erythromycin, Ciprofloxacin) against multi-antibiotic resistance bacteria were also investigated. The result showed the synergistic action of AgNPs and antibiotics leading to enhance antibacterial activity.
Production of Functional Yogurt Drink, Apple and Orange Juice Using Nano-Encapsulated L. brevis Within Sodium Alginate-Based Biopolymers

The study objective was to improve functional properties of yogurt drink, apple and orange which were produced by addition of free and encapsulated probiotics. For this purpose, probiotic L. brevis E25 bacterial cells were encapsulated in sodium alginate by electrospinning method. In this study, Fourier-transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), XRD, and Nuclear Magnetic Resonance (NMR) techniques were used to characterize the L. brevis encapsulated with nanofiber. The free and nano-encapsulated probiotic bacteria were inoculated into ayran, apple and orange juice, where bacterial viability, pH, brix and color were assessed each 3 days for the ayran and each week for the apple and orange juice for six-week period. The encapsulated probiotic organisms showed an important survival ratio in the three products comparing to the free probiotic bacteria, where the pH and the brix showed no decreasing leading to conclude that the nanoencapsulation of probiotic L. brevis cell using the electrospinning method lead to functional yet more stable food and have the potential of increased benefits.
Alta correlación en la detección de anticuerpos y antígenos de virus del dengue en muestras de suero y plasma

Introduccion. El diagnostico adecuado de dengue por laboratorio es importante para la atencion, asi como para el control de brotes y epidemias. Hasta el momento, las pruebas ELISA para diagnostico serologico de la infeccion se encuentran validadas en muestras de suero; sin embargo, en algunas ocasiones la cantidad o calidad de la muestra es inadecuada, o solo se tiene acceso a sangre anticoagulada tomada para el analisis de los parametros hematologicos en el hemograma. Objetivo. Evaluar el desempeno de cuatro pruebas ELISA en muestras de suero y plasma de casos sospechosos de dengue. Materiales y metodos. Se procesaron 42 muestras —21 de suero y 21 de plasma— por las tecnicas de ELISA de captura para IgM, ELISA de captura para IgG, ELISA indirecta para IgG y ELISA para la deteccion del antigeno viral NS1. Resultados. El porcentaje de muestras positivas encontrado fue IgM 33.3%, IgG Captura 33.3%, IgG Indirecta 90.5%, NS1 23.8%. El 42.9% de las muestras fueron positivas por RT-PCR (n=9). Todas las pruebas se comportaron igual tanto en sueros como plasmas (coeficiente Kappa 1.0). Conclusion. Los resultados obtenidos muestran una alta concordancia entre las mediciones realizadas en suero y en plasma, lo cual sugiere que la muestra de plasma puede utilizarse para el diagnostico y la confirmacion de los casos de dengue.
Antiapoptotic and cardioprotective effects of a herbal combination in rats with experimental myocardial infarction

efficacy of the combination of herbal extracts of Ocimum sanctum, Withania somnifera and Curcuma longa (HCB) to limit myocardial injury in an open chest left anterior descending coronary artery (LAD) ischemia and reperfusion (I-R) experimental model was evaluated. Wistar albino rats were divided into four groups and orally fed saline once daily (sham, control IR) or HCB (HCB, HCB-IR) groups respectively for 1 month. On the 31 st day the rats of the Control IR and HCB-IR groups LAD was occluded for 45 min, and reperfused for 1h. Hemodynamic parameters were recorded and subsequently sacrificed for biochemical, immunohistochemical and pathological studies. In the control IR group, significant ventricular dysfunction, cardiac necrosis, apoptosis; decline in antioxidant status and elevation in lipid peroxidation. HCB treatment significantly reduced the surrogate preload marker LVEDP and improved both inotropic and lusitropic function of the heart as compared to sham. HCB significantly increased GSH content and SOD, CAT, GSHPx (p<0.001) activity, decreased level of TBARS (p<0.01)} as compared to control IR group. Most importantly, HCB decreased Bax (p<0.01), upregulated Bcl-2 (p<0.001) expression and attenuated TUNEL positivity (p<0.01). Cardioprotection by HCB treatment may be attributed to its favorable hemodynamic effects, myocardial adaptogenic, antioxidant and antiapoptotic properties.