Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of blue light spectrum filter on short-wavelength and standard automated perimetries.

PURPOSE To evaluate the influence of a blue light spectrum filter (BLSF), similar in light spectrum transmittance to the intraocular lens Acrysof Natural, on standard automated perimetry (SAP) and short-wavelength automated perimetry (SWAP). METHODS Twenty young individuals (< 30 y.o.), without any systemic or ocular alterations (twenty eyes) underwent a random sequence of four Humphrey visual field tests: standard automated perimetry (SAP) and short-wavelength automated perimetry (SWAP) with and without a blue light spectrum filter. All patients had intraocular pressure lower than 21 mmHg, normal fundus biomicroscopy, and no crystalline lens opacity. Foveal threshold (FT), mean deviation (MD), and pattern standard deviation (PSD) indexes obtained from the visual field tests and the difference caused by eccentricity in short-wavelength automated perimetry examinations were analyzed using paired t test. Interindividual variability (standard deviation) was calculated using Pitman's test for correlated samples. RESULTS Statistically significant reductions in the mean deviation (p < 0.001) and in the foveal threshold (p < 0.001) measured by short-wavelength automated perimetry with the use of the blue light spectrum filter in comparison to short-wavelength automated perimetry without the use of the blue light spectrum filter were observed, but not in standard automated perimetry exams. No other parameters showed statistically significant differences in the short-wavelength automated perimetry and standard automated perimetry tests. Interindividual standard deviation of the test points in the short-wavelength automated perimetry exams increased with eccentricity both with and without the use of the blue light spectrum filter, as sensitivity for inferior and superior hemifields (inferior hemifield minus superior hemifield), but no statistically significant difference in the variability when comparing the use or not of the blue light spectrum filter was noted. When comparing only the four most inferior points and the four most superior points, the inferior-superior difference increases in both situations - without and with the use of the blue light spectrum filter. The difference between without and with the use of the blue light spectrum filter was not statistically significant. CONCLUSION Statistically significant reductions in mean deviation and foveal threshold in the short-wavelength automated perimetry with the use of the blue light spectrum filter were observed, but not in standard automated perimetry examinations. Additional studies are necessary to determine the influence of intraocular lenses with short-wavelength light filter after cataract extraction on short-wavelength automated perimetry.
[Indicators of pulmonary epithelial damage among workers at a foundry exposed to airborne pollutants].

Foundry ambient air contains very high concentrations of noxious substances, such as particulate matter and gaseous pollutants, which can target the respiratory epithelium. Serum concentrations of the 16-kDa Clara cell protein (CC16-S) may reflect both the integrity of the epithelial barrier and smoke-induced Clara cell toxicity. To evaluate whether CC16-S is a sensitive biomarker of early respiratory disturbances, it was determined in a group of 35 foundry male workers (aged 41.1 +/- 6.9 years) examined both prior to and at the end of their work-shift (06:00 a.m.-02:00 p.m.). Exposure to inhalable/respirable dusts and PAH was characterized; urinary excretion of 1-hydroxypyrene (1-OH-P) and naphtol was measured to assess exposure to pyrene and naphthalene, respectively. CC16 serum levels decreased at the end of the shift (10.7 +/- 3.82 micrograms/L vs. 8.39 +/- 3.05 micrograms/L; p < 0.01); such decrements were significantly larger in more exposed workers. Although smokers had lower baseline values as compared to non smokers, both subgroups showed an average decrease of 30% in CC16-S concentrations at the end of shift. CC16-S was also negatively correlated with 1-OH-P, but not with naphtol concentrations. Decreased CC16-S levels can result from citotoxicity and would represent an useful biomarker of pneumotoxicity in foundry workers exposed to complex mixtures.
Socket Shield Technique for immediate implant placement – clinical, radiographic and volumetric data after 5 years

OBJECTIVES Implant placement immediately after tooth extraction is often accompanied by resorption of surrounding tissues. A clinical technique was developed where the buccal portion of the root is retained to preserve the periodontal ligament and bundle bone. This technique is based on animal studies showing the potential to preserve the facial tissues utilizing this approach. The purpose of this study was to gain more insight regarding the safety of the technique with regard to biological and implant-related long-term complications and to observe the clinical appearance of the peri-implant tissues. Another objective was to evaluate volumetric changes of the affected facial contours in long-term and the esthetic outcomes. MATERIAL AND METHODS This study is a retrospective case series of 10 consecutive patients with implant replacement between the maxillary first premolars. Impressions were made prior to extraction (t1) and 5 years post-implant placement (t2). 3D-surface scans of the casts were digitally superimposed for quantitative evaluation of alterations of the facial peri-implant tissue contours and soft tissue recessions. Additionally, clinical data were collected (PPD, BOP, peri-apical radiographs and photographs). RESULTS All implants healed without adverse events. Peri-implant probing revealed healthy conditions. The comparison of radiographic images showed physiologic bone remodeling at the implant shoulders. Mean tissue loss on the facial side in oro-facial direction was -0.21 ± 0.18 mm. Average recession at implants was -0.33 ± 0.23 mm and at neighboring teeth -0.38 ± 0.27 mm. Mean loss of the marginal bone level at the implant shoulder amounted to 0.33 ± 0.43 mm at the mesial and 0.17 ± 0.36 mm at the distal aspect of the implants. A mean pink esthetic score of 12 was recorded. CONCLUSION Volumetric analysis showed a low degree of contour changes from extraction and implant placement to the follow-ups. Mucosal recession at the implant restoration was comparable to that of the neighboring teeth. Within the limitations of this descriptive study, the socket shield technique offers reduced invasiveness at the time of surgery and high esthetic outcomes with effective preservation of facial tissue contours. This technique should not be used in routine clinical practice until a higher level evidence in the form of prospective clinical trials is available.
Aspirin in the secondary prevention of cardiovascular disease: an update of the APTC meta‐analysis

We updated the 2002 Antiplatelet Trialists’ Collaboration meta‐analysis of antiplatelet therapy to assess the effects of aspirin alone in the secondary prevention of different types of thrombotic arterial disease. Results of randomized, placebo‐controlled trials of aspirin in patients with confirmed cardiovascular disease were abstracted and synthesized by the Mantel–Haenszel method. We defined three cardiovascular disease groups according to the qualifying disease at entry: coronary artery disease (CAD), cerebrovascular disease (CRVD), and peripheral arterial disease (PAD). Results are given as odds ratios (OR) and 95% confidence intervals (95% CI). Compared with placebo, aspirin decreased significantly the risk of all‐cause death in CAD and CRVD (OR = 0.80, 95% CI 0.75–0.86 and 0.91, 95% CI 0.85–0.98, respectively), and of vascular events in CAD, CRVD, and PAD (OR = 0.71, 95% CI 0.67–0.76, 0.87, 95% CI 0.82–0.93, and 0.50, 95% CI 0.29–0.88, respectively). The risk of non‐fatal stroke was decreased in the CAD, CRVD, and PAD (OR = 0.64, 95% CI 0.50–0.83, 0.81, 95% CI 0.74–0.89, and 0.26, 95% CI 0.07–0.94, respectively). The risk of non‐fatal myocardial infarction was decreased significantly in the CAD and CRVD (OR = 0.59, 95% CI 0.53–0.67, and 0.63, 95% CI 0.48–0.84, respectively), but not in the PAD (OR = 0.43, 95% CI 0.15–1.25). Aspirin nearly doubled the risk of major bleeds (OR = 1.87, 95% CI 1.51–2.32 for all clinical conditions). This meta‐analysis confirms that aspirin decreases the risk of thrombotic events in patients with confirmed disease of the coronary, cerebrovascular, or peripheral artery beds.
ISLAMIC BUSINESS ETHICS BETWEEN REALITY

Abstrak : Sesungguhnya sejarah etika bisnis Islam tidak dapat dipisahkan dari sejarah induknya yakni ekonomi Islam, sedangkan ekonomi Islam berusia setua Islam itu sendiri. Sebagaimana kita ketahui, misi mulia Rasulullah SAW. di muka bumi adalah membangun masyarakat yang beradab. Adapun prinsip-prinsip dasar etika bisnis Islam yang ditanamkan oleh Rasulullah adalah sebagai berikut: (1) berlandaskan ketauhidan (keesaan), (2) keadilan (keseimbangan), (3) kebebasan berikhtiyar, (4) amanah (bertanggung jawab), (5) menegakkan kebenaran, kebajikan dan kejujuran. Dalam konteks keindonesiaan, penegakan hukum dalam bisnis sebenarnya sebagian besar sudah dilaksanakan, meskipun pelaksanaannya berbeda dengan bisnis yang dijalankan pada masa awal peradaban Islam. Pada awal peradaban Islam sudah terdapat lembaga pengawasan ( al- h isbah ) yang fungsinya adalah meninjau keberadaan bisnis di pasar, baik dari segi halal dan haramnya produk yang dijual, ukuran timbangan, kejujuran seorang penjual, dan hal-hal lain yang merugikan. Ukuran penegakan hukum di Indonesia didasarkan atas klausul yang menyangkut hal-hal yang merugikan orang lain, bukan terkait halal dan haramnya produk. Dalam implementasinya diharapkan pelaku bisnis mampu melaksanakan dengan menekankan pada cara yang dikenalkan Islam dalam etika berbisnis yang Islami. Bisnis dalam bidang-bidang yang halal, bermanfaat positif, tidak dengan penipuan, harus disampaikan dengan apa adanya (jujur), serta tidak merusak lingkungan dan ekosistem yang lainnya. Abstract: Actually, the history of the Islamic business ethics cannot be separated from its parent’s history which is the Islamic economics, whereas the Islamic economics is as old as the religion of Islam itself. As we know, the noble mission of the Prophet Muhammad (peace be upon him) in this world is to build a civilized society. The basic principles of Islamic business ethics instilled by Muhammad is follows: (1) based on taw h id (oneness of Allah), (2) justice (balance), (3) freedom to make efforts (4) amânah (being responsible), (5) upholding the truth, virtues, and honesty. In the context of Indonesian-ness, actually in the business of law enforcement, it has been mostly implemented, although the implementation is different when the business is run in the early days of Islamic civilization. At the beginning of Islamic civilization it is available an oversight agencies ( al- h isbah ) whose function is to review business presence in the market, in terms of both lawful and illicit products sold, the size of the scales, the honesty of a seller and other things that harm. The standard measurement of law enforcement in Indonesia is based on the clause related to harm others, not related to halâl and h arâm products. In its implementation it is expected that the practice of businesses can be done by emphasizing ways introduced by Islam in the Islamic busines ethics. Business in the law full field with positive benefit, non by froud, should be stated as for what it is (honest), by not to damage the environment and other ecosystems Kata Kunci : Islamic busines, ethics, Taw h id, Amânah, al- H isbah
Fabrication of RF Magnetic Shielding Plate Having the Polarization Characteristics

As one of the basic areas of research for the improvement of the electromagnetic environment, the present paper has developed the carbon plate having the polarization characteristics. To exhibit the polarization characteristics in the far field region, it has formed the slit on the surface of carbon plate. The value of the RF magnetic shielding degree SDHH for holding the slit of a carbon plate horizontally, in the frequency region of 1 MHz to 1 GHz, increased with frequency, and had the value of 58 dB at 1 GHz. Also shown that the value of SDHP for holding the slit perpendicularly indicated about 10 dB in the frequency region of 1 MHz to 1 GHz. Namely, the difference of shielding degrees of the carbon plate to direction of slit is indicated the polarization characteristics. Experimental results revealed several characteristics of the slitting carbon plate that include the influences of polarization characteristics on the slit length L and slit number N. In the present paper, it is improved the polarization characteristics by the superposition of slitting ferrite plate over a slitting carbon plate, termed a compound plate. In addition, important criteria are discussed for the design of an effective RF magnetic shielding plate having polarization characteristics.
Orally Administered Ginseng Extract Reduces Serum Total Cholesterol and Triglycerides That Induce Fatty Liver in 66% Hepatectomized Rats

The effects of ginseng extract (from the root of Panax ginseng) on factors inducing fatty liver were examined in 66% hepatectomized rats. Oral administration of ginseng extract at 125 or 250 mg/kg/day produced statistically significant reductions in total cholesterol and triglyceride concentrations in the blood 3 days after hepatectomy (P < 0.05); the total cholesterol response appeared to be dose-related. Administration of ginseng extract at both doses also reduced total cholesterol and triglyceride concentrations in the liver 3 days after hepatectomy. Food intake and serum chemistry parameters indicating liver and kidney function were unchanged after ginseng administration except for the lipid metabolic parameters. These observations suggest that orally administered ginseng extract can suppress the formation of fatty liver after hepatic resection.
Why don't physicians test for HIV? A review of the US literature

Objective:In its 2006 HIV testing guidelines, the Centers for Disease Control and Prevention (CDC) recommended routine testing in all US medical settings. Given that many physicians do not routinely test for HIV, the objective of this study was to summarize our current understanding of why US physicians do not offer HIV testing. Design:A comprehensive review of the published and unpublished literature on HIV testing barriers was conducted. Methods:A literature search was conducted in Pubmed using defined search terms. Other sources included Google, recent conference abstracts, and experts in the field. Studies were divided into three categories: prenatal; emergency department; and other medical settings. These categories were chosen because of differences in physician training, practice environment, and patient populations. Barriers identified in these sources were summarized separately for the three practice settings and compared. Results:Forty-one barriers were identified from 17 reports. Twenty-four barriers were named in the prenatal setting, 20 in the emergency department setting, and 23 in other medical settings. Eight barriers were identified in all three categories: insufficient time; burdensome consent process; lack of knowledge/training; lack of patient acceptance; pretest counselling requirements; competing priorities; and inadequate reimbursement. Conclusion:US physicians experience many policy-based, logistical, and educational barriers to HIV testing. Although some barriers are exclusive to the practice setting studied, substantial overlap was found across practice settings. Some or all of these barriers must be addressed before the CDC recommendation for routine HIV testing can be realized in all US medical settings.
Number of mitral cells and the bulb volume in the aging human olfactory bulb: A quantitative morphological study

The present study documents the morphological changes in the aging human olfactory bulb. Eight bulb pairs from white females between the ages of 25 and 102 years were used. The number of mitral cells in layers IV and III was determined for each bulb and corrected for spilt cell error. Counts were made on 10‐μm thick Nissl‐stained sections at 250‐μm intervals. The mean number of mitral cells per olfactory bulb at age 25 was estimated from linear regression to be 50,935; at age 60, 32,718; and at age 95, 14,501. The average loss over the time interval studied was 520 mitral cells per year.
Internet addiction, academic performance and personality traits: a correlational study among female university students

This study examines the relationship of internet addiction with personality, academic performance, and internet self-efficacy in the context of higher education. In addition, the study investigates the relationship between two questionnaires that measure internet addiction: the internet addiction test () and the online cognition scale (OCS). The study sample was 110 Greek female students at their second year of studies in educational sciences. Participants completed the following questionnaires: internet self-efficacy (ISE), Big Five personality test (Big Five), internet addiction test (IAT) and online cognition scale (OCS). Questions on participants' demographics and internet usage experience were also used. A moderate negative significant correlation was found between personality and internet addiction. The highest magnitude of this negative correlation was observed for the Big Five emotional stability trait. Internet addiction did not significantly correlate with academic performance, nor did it significantly correlate with internet self-efficacy. Moreover, no significant correlation was found between academic performance and internet self-efficacy. Finally, a strong positive significant correlation was found between IAT and OCS.
Effects of feeding low protein diets to piglets on plasma urea nitrogen, faecal ammonia nitrogen, the incidence of diarrhoea and performance after weaning

This study evaluated the effects of feeding pigs low protein (LP) diets for different lengths of time after weaning on indices of protein fermentation, the incidence of post-weaning diarrhoea (PWD), growth performance, and total-tract apparent digestibility. Sixty weaner pigs weighing 6.1 ± 0.13 kg (mean ± SEM) were used in a completely randomised design having five treatments: (i) a high protein diet (HP, 243 g/kg CP) fed for 14 d after weaning (HP14); (ii) a low protein diet (LP, 173 g CP/kg) fed for 5 d after weaning (LP5); (iii) LP diet fed for 7 d after weaning (LP7); (iv) LP diet fed for 10 d after weaning (LP10), and (v) LP diet fed for 14 d after weaning (LP14). All diets were supplemented with lysine, methionine, tryptophan and threonine, with all LP diets additionally fortified with crystalline isoleucine and valine to conform to a proposed ideal amino acid (AA) pattern. A second-stage diet (215 g CP/kg) was fed to pigs at the conclusion of each treatment. None of the diets contained antimicrobial compounds. Feeding a LP diet, regardless of duration of feeding, decreased plasma urea nitrogen (p < 0.001) and faecal ammonia-nitrogen (p < 0.001) contents. Feeding a LP diet, irrespective of feeding duration, decreased the incidence of PWD at day 8 after weaning (p = 0.044), and pigs fed diets LP7, LP10 and LP14 had firmer faeces (p = 0.030, p = 0.047 and p = 0.007, respectively) between days 10 and 12 after weaning. Treatments LP5, LP7, LP10 and LP14 did not reduce (p > 0.05) growth performance up to 106 days after weaning compared to pigs fed the HP diet. Total-tract apparent digestibility of dry matter, energy and crude protein were similar (p > 0.05) between treatments. Our data suggest that feeding a LP diet, supplemented with AA to conform to an ideal AA pattern, for 7–10 days after weaning can reduce PWD in pigs fed antibiotic-free diets without compromising production.
The proprotein convertase furin in tumour progression

Proprotein convertases are proteases that have been implicated in the activation of a wide variety of proteins. These proteins are generally synthesised as precursor proteins and require limited proteolysis for conversion into their mature bioactive counterparts. Many of these proteins, including metalloproteases, growth factors and their receptors or adhesion molecules, have been shown to facilitate tumour formation and progression. Hence, this review will focus on the proprotein convertase furin and its role in cancer. The expression of furin has been confirmed in a large spectrum of cancers such as head and neck squamous cell carcinoma, breast cancer and rhabdomyosarcoma. Functional studies modulating furin activity uncovered its importance for the processing of many cancer‐related substrates and strongly indicate that high furin activity promotes the malignant phenotype of cancer cells. In this review, we summarise the expression and function of furin in different cancer types, discuss its role in processing cancer‐related proproteins and give examples of potential therapeutic approaches that take advantage of the proteolytic activity of furin in cancer cells.
A prospective study of postoperative surgical site infections in dogs and cats.

OBJECTIVE To assess postoperative surgical site infection (SSI) rate and to identify associated predictive factors. STUDY DESIGN Prospective clinical study. ANIMALS Dogs and cats that had surgery (1010 interventions) during 58 weeks from April 1999 to June 2000. METHODS Data sheets were completed by clinicians. Patients were controlled for clinical evidence of SSI at suture removal. Two definitions of SSI ("infection" and "infection/inflammation") were developed specifically for this study and used for statistical analysis. Logistic regression models were built in order to identify significant predictive factors for SSI. RESULTS Wounds with "infection/inflammation" occurred in 5.8% and "infected" wounds in 3% of patients. The outcome "infection" was associated with 3 major risk factors (duration of surgery, increasing number of persons in the operating room, dirty surgical site) and 1 protective factor (antimicrobial prophylaxis). The outcome "infection/inflammation" was associated with 6 significant factors (duration of anesthesia, duration of postoperative intensive care unit stay, wound drainage, increasing patient weight, dirty surgical site, and antimicrobial prophylaxis). CONCLUSIONS SSI frequency in companion animals is comparable with the frequency observed in human surgical patients. Several significant predictive factors for SSI in small animals surgery were identified. CLINICAL RELEVANCE Baseline information for SSI surveillance in our hospital and for comparison with other studies was defined. The factors identified may help to predict infections in surgical patients and to take adequate preventive measures for patients at risk.