Miracle-dz/UniFAR-FTUs huggingface dataset:
Incision Techniques Used Second Stage Surgery For Peri-implant Soft Tissue Esthetic

The main purpose of the anterior implants is obtaining esthetically natural look. For providing this view, the reconstruction of the papillary region and prevention of buccal soft tissue recession is necessary. For generating papilla and enhance buccal gingival thickness, techniques that used only incision while second stage surgery are increasing day by day. The common objective of the incision techniques and flap designs is protect and provide the periimplant soft tissue esthetic. Second stage surgery is convenient time for manipulations of soft tissue. The incision techniques which used in this stage must aid papilla regeneration and buccal tissue growth. In this review we aimed to study the techniques that used second stage surgery for achiving peri-implant soft tissue esthetic.
To study the Prevalence of obesity among medical students in relation with dietary habits

Introduction: Worldwide obesity has nearly tripled since 1975.In 2016, 39% adults of 18 years and above were overweight and 13% were obese. Approximately 2.8 million deaths are reported as a result of being overweight or obese. Unhealthy food style, lack of physical activity, and stress are the major factors which contribute to obesity. So this study was done with the aim to estimate the prevalence of obesity among the Medical College students. To access the knowledge about risk factors causing obesity and to take preventive measures to avoid it as they are health educators of community. Objective: To determine the prevalence of obesity in medical students, to access their knowledge towards risk factors of obesity Material and Methods: A cross-sectional study was conducted among 500 medical students of D.Y. Patil Medical College Navi Mumbai from Jan - June 2019. Consent was obtained from the study participants after explaining the purpose of study. Data was collected using a pre-tested, semi-structured, self administered questionnaire which was validated by department of community Medicine. Anthropometric measurements were taken and body mass index was calculated. Descriptive statistics was used to analyze the data. Results: The prevalence of overweight and obesity were 36.8% and 11.1%. Overweight and obesity were more observed in boys (48.8 %, 11.6%) than girls (30%, 10.55%). Conclusions: The prevalence was found to be high among medical college students which were contributed by various risk factors. This can be reduced by modifying their diet, engaging in regular physical activity. Keywords: Obesity, body mass index, Medical students
A Diagnosis of Anisotropic Eddy Diffusion From a High‐Resolution Global Ocean Model

Oceanic mesoscale eddies are known to diffuse and stir tracers, and the development of skillful eddy closures is aided considerably by the accurate diagnosis of these processes from eddy‐resolving model statistics. In this work a multiple‐tracers inversion method is applied to a global mesoscale eddy‐resolving simulation, with the intent to solve for the eddy transport tensor that describes the eddy diffusion (symmetric part) and stirring (antisymmetric part). Special emphasis is placed on diagnosing the anisotropy of the horizontal transport, which is described by the eigenvalues and eigenvectors of the 2×2 horizontal symmetric subtensor. Global diagnoses of these quantities, along with an examination of their vertical structures, are used to recommend an algorithm for extending the Gent and McWilliams and Redi parameterizations to include anisotropic effects.
Eventos adversos relacionados con las prácticas asistenciales: una revisión integradora

Objective: To identify the scientific publications about adverse events related to practical assistance and discuss the culture of patient safety. Methods: An integrative literature review was done through research in MEDLINE, LILACS and BDENF available in BVS, using the following descriptors: patient safety, patient assistance, surveillance of sentinel event, safety management. 26 scientific articles published in the period defined for this review, 2005 to 2015 met the inclusion criteria. Results: The analysis of the articles revealed five major categories: characteristics of adverse events related to practical assistance, adverse events occurrence implications, measures for the prevention of adverse events, notifications of adverse events and the intervenient factors and the knowledge and the culture of safety. Conclusion: The punitive culture comes as responsible for underreporting and omission of adverse events, being constituted a barrier to effective implementation of investigations. It is essential to foster a safety culture to establish strategies that ensure the care provision free of damage.
The production of 4-ethyltoluene via directional valorization of lignin

4-Ethyltoluene is a very valuable chemical that is currently produced from fossil feedstocks. Production of 4-ethyltoluene from renewable and cheap lignin is of great significance. Herein, we report a new route to produce 4-ethyltoluene from lignin. It was discovered that RhCl3-LiI-LiBF4 was an efficient catalytic system for the reaction of lignin with CO to form 4-ethyltoluene. In the reaction, ethylbenzene was first formed via demethoxylation and depolymerization of lignin, which was further transformed into 4-ethyltoluene by methylation using methoxy from the lignin. The yield of 4-ethyltoluene could reach 9.5 wt% when GVL-lignin was used as the starting material. Interestingly, 5.2 wt% yield of 4-ethyltoluene was obtained when raw poplar was directly used as the starting material. As far as we know, the transformation of lignin with 4-ethyltoluene as the major product has not been reported. This work provides a new strategy to produce valuable aromatic compounds from renewable resources.
Revelation of New Compound from Ethanolic Extract of Fragaria x ananassa var. Lembang

Fragaria x ananassa (strawberry) is a subtropical plant that can adapt well in tropical highlands. Fragaria x ananassa have been widely used to cope with health problems. The active compound component of secondary metabolites contained in Fragaria x ananassa has the potential as an antioxidant. This research is done to isolate secondary metabolites from extract of Fragaria x ananassa fruits. Extract Fragaria x ananassa was produced by maceration using ethanol as the solvent. Separation and isolation compound were carried out using Vacuum Liquid Chromatography (VLC) and Gravity Column Chromatography (GCC) guided by Thin Layer Chromatography (TLC) using hexane: ethyl acetate (3:7) as the eluent. The flavonoid compound was determined by the total content of phenolic and flavonoid in extract of Fragaria x ananassa fruits. The results of total phenolic content and total flavonoid content were 0.1130 mg/g and 0.0112 mg/g, respectively. The alkaloid compound was determined by Dragendorff testing. The elucidation of the structure by Fourier Tansform Infrared (FTIR), Nuclear Magnetic Resonance (NMR), and Liquid Chromatography Mass Spectrometry (LCMS) showed that the active compound contained in the secondary metabolite of extract ethanol from Fragaria x ananassa is 3-Cyclopentyl-5-(1-hydroxyethyl)-1,6-dihydro-7H-pyrazolo[4,3- d]pyrimidin-7-one. Keywords: Fragaria x ananassa extract, flavonoid, alkaloid, total phenolic and flavonoid content, FTIR, NMR, LCMS.
COMPENSATION AND WORKER COMMITMENT IN OIL SERVICING COMPANIES IN RIVERS STATE, NIGERIA

This study investigated the relationship between compensation and worker commitment in oil servicing companies in Rivers State, Nigeria. Compensation is an essential component in maintaining the best employees and establishing an organization for the increasing competitive globe limit. Compensation can be defined as a benefit that an employee get in return for the work rendered to the organization. For the purpose of this study, Three hundred and two (302) copies of structured questionnaire using five (5) point likert scale were administered to respondents of the oil servicing companies in Rivers State, Nigeria. Out of the three hundred and two (302) copies of structured questionnaire, two hundred and ninety-eight (298) copies were completed, filled and used representing a respond rate of 99.3%. The formulated researches Hypotheses were tested using the Spearman’s Rank Order Correlation Coefficient statistical tool and the results prove that compensation persuades affective and continuance commitment. Keywords: Compensation, Worker commitment, Affective commitment, and Continuance commitment. CITATION: Nwaiwu, J. C. , & Onuoha, C. (2020). Compensation and worker commitment in oil servicing companies in Rivers State, Nigeria. The Strategic Journal of Business & Change Management, 7(1), 505 – 512.
Investigation of the functional stability limits while squatting

This study investigates the functional stability limits (FSLs) in the squatting positions. Eleven male participants leaned and moved their pelvis horizontally in the clockwise and counter‐clockwise directions while squatting at 11 depth levels. The depth was controlled by changing the hip height from 100% to 0% of the upright position. The FSLs and the center of pressure excursion lengths were calculated from the force‐plate data, and the musculoskeletal loads on the lower limbs were estimated from the joint torques and surface electromyograms. As the hip height reduced, the area of the FSLs narrowed by up to 20% of the base of support (BOS) area at the deepest squatting position. The narrowing was affected by the decreasing FSLs in the forward direction, which also decreased by up to 20% of BOS. These quantitative data accurately evaluate the postural stability, suggesting a considerable fall risk during tasks requiring the squatting position.
Line of sight implementation for game platformer

Traditional weapon is one of cultural heritage from our ancestors in Indonesia. While it can be noted that the popularity of less traditional weapons in the know by many people because it is losing popularity with weapons from other countries. But now there are some people who make use of media technology to preserve the traditional cultures ranging from custom homes, traditional clothing and also a traditional weapon from every province in Indonesia. Be aware that in Indonesia traditional weapon there are diverse, but some provinces have the same traditional weapons it can because the province having the same family or experience the separation area. So, on the development level, authors will make the concept of continuous Boss for some provinces that have same traditional weapons. In addition to developing a level of the game, the author also applied line of sight method on the boss enemy.
Preparation of cellulose nanocrystals using highly recyclable organic acid treated softwood pulp

Cellulose nanocrystals (CNC) were successfully obtained from softwood pulp by p-toluenesulfonic acid (p-TsOH) hydrolysis under the treatment of p-TsOH mass concentration of 60%, temperature of 70 °C, reaction time of 4 h, and pulp to solution ratio of 1:20 (g / mL). Zeta potential and dynamic light scattering (DLS), scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), and thermogravimetric analysis (TGA) were used to characterize the physical-chemical properties of the CNC. Under these conditions, the CNC exhibited good thermal stability in the suspension with a high crystallinity index of 90.1%. The CNC had an average diameter of 4.87 nm and average length 175.5 nm with no undesired elemental contamination. The degradation temperature of the CNC was relatively high at 310 °C. Moreover, p-TsOH was recovered by crystallization technology, and the recovery rate was over 70%, providing an environmentally friendly way for the development of biomass materials.
Essays in planning policy and urban economics

This thesis consists of four independent chapters. Although the chapters are distinct works, they are related by their focus on urban policy and aim to contribute to the understanding of how planning policies and urban development affect specific outcomes in space. The chapters can be divided into two distinct parts. The first part comprises two studies on conservation planning. The first chapter investigates the complexities at play between conservation planning systems, their applications and how these vary between contexts. Based on a survey of conservation planning systems in 5 countries, focusing on 5 city case-studies, it considers how conservation compares between planning systems of the Global North and Global South and what this suggest about heritage value. The second chapter exploits the Italian context to examine to what extent non-compliance undermines conservation effects given that despite stringent planning regulation, the conditions of the urban environment vary widely throughout Italy, including within protected areas. This study is closely linked to the urban economics literature through an explicit consideration of housing markets and spatial issues. The second part of this thesis comprises two further chapters that focus on the effects of two distinctly urban occurrences: economic and morphological density. The third chapter investigates the costs and benefits of a widely supported policy paradigm: ‘compact urban form’. It asks to what extent even higher densities within cities are desirable by assessing the effects of density on a broad range of outcomes ranging from wages, innovation, rents, various amenities, the cost of providing public services, transport- and environment-related outcomes to health and wellbeing. The final chapter focuses on deregulated planning using Beirut, Lebanon as a case-study given the city’s conspicuous transformations which have dramatically altered the city’s landscape, housing stock, and people-space relations. This chapter specifically investigates how morphological densification affects values residents attach to both their physical urban environments and intangible urban amenities such as neighbourhood belonging. The unifying theme of the thesis is to bring fresh evidence to policy-relevant issues in planning and urban economics by the generation of new datasets for all contexts and the application of multi-disciplinary techniques.
Abstract 1809: PKM2 promotes tumor angiogenesis by regulating HIF-1alpha through NF-kappaB activation

Initially identified as a molecule that catalyzes the phosphorylation from phosphoenolpyruvate to pyruvate in the final step of glycolysis, the M2 isoform of pyruvate kinase (PKM2) was recently reported to have a central role in the metabolic reprogramming of cancer cells as well as participating in the regulation of apoptosis and proliferation. In this study, we have identified PKM2 as a crucial molecule for progression of pancreatic cancer in which tumor microenvironment has been reported to be highly hypoxic. Our data show moderate to strong PKM2 expression in all examined human pancreatic adenocarcinoma samples. Depletion of PKM2 was associated with impaired proliferation and augmented tumor cell death in vitro, while the in vivo tumor xenograft experiments revealed a close association between impaired tumor growth and decreased blood vessel formation. Furthermore, abrogation of PKM2 prevented hypoxia-mediated HIF-1alpha accumulation and HIF-1alpha promoter activity, which negatively impacted VEGF secretion by pancreatic cancer cells deprived of oxygen. Interestingly, PKM2 expression arrest was also mirrored by impaired hypoxia-driven promoter activity of NF-kappaB which also drives the transcription of VEGF. Ectopic expression of p65 restored VEGF transcription after PKM2 ablation inferring that the kinase regulates VEGF via NF-kappaB/p65 subunit. Altogether, our study suggests that in hypoxic pancreatic tumors PKM2 interferes both with NF-kappaB/p65 and HIF-1alpha activation that ultimately triggers VEGF-A secretion and subsequent blood vessel formation. Citation Format: Ninel Azoitei, Alexander Becher, Konrad Steinestel, Arefeh Rouhi, Kristina Diepold, Susanne Bobrovich, Thomas Seufferlein. PKM2 promotes tumor angiogenesis by regulating HIF-1alpha through NF-kappaB activation [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 1809. doi:10.1158/1538-7445.AM2017-1809
Water potential gradient, root conduit size and root xylem hydraulic conductivity determine the extent of hydraulic redistribution in temperate trees

Hydraulic redistribution (HR) of soil water through plant roots is widely described; however its extent, especially in temperate trees, remains unclear. Here, we quantified HR of five temperate tree species. We hypothesized that both, HR within a plant and into the soil increase with higher water‐potential gradients, larger root conduit diameters and root‐xylem hydraulic conductivities as HR driving factors. Saplings of conifer (Picea abies, Pseudotsuga menziesii), diffuse‐porous (Acer pseudoplatanus) and ring‐porous species (Castanea sativa, Quercus robur) were planted in split‐root systems, where one plant had its roots split between two pots with different water‐potential gradients (0.23–4.20 MPa). We quantified HR via deuterium labelling. Species redistributed 0.39 ± 0.14 ml of water overnight (0.08 ± 0.01 ml/g root mass). Higher pre‐dawn water‐potential gradients, hydraulic conductivities and larger conduits significantly increased HR quantity. Hydraulic conductivity was the most important driving factor on HR amounts, within the plants (0.03 ± 0.01 ml/g) and into the soil (0.06 ± 0.01 ml/g). Additional factors as soil‐root contact should be considered, especially when calculating water transfer into the soil. Nevertheless, trees maintaining high‐xylem hydraulic conductivity showed higher HR amounts, potentially making them valuable ‘silvicultural tools’ to improve plant water status. A free Plain Language Summary can be found within the Supporting Information of this article.
Determining the input impedance of ECG amplifiers using accurate electrode modelling

Objective: The influence of the skin-electrode-amplifier interface and the input impedance of ECG recording amplifiers on transient response performance is investigated using accurate modeling of surface contact electrodes. The paper aims to establish the input impedance requirements of ECG recording amplifiers based on the electrical properties of the electrodes. Approach: The IEC 60601 standard stipulates the performance requirements for electrocardiographs. Analyses and simulation of both dc and ac modes of coupling the electrodes to the input of the amplifier have been undertaken using an accurate double time-constant model of the electrodes in order to establish design constraints for amplifier input impedance to meet this performance specification. These have been backed up with bench tests. Main Results: Investigations carried out indicate that the minimum 10 MΩ resistance at the amplifier input recommended in the specification is insufficient when using some modern adhesive electrodes and increasingly popular un-gelled or dry electrodes. Design constraints are established based on the electrical properties of the electrodes. These constraints suggest that the input impedance of the amplifier should be as high as 10 GΩ and the amplifier ac coupled cut-off frequency should not to be higher than 0.05 Hz for all the electrode models considered. Significance: Signal distortions in the form of false S-wave creation and depression of the S-T segment have been observed when the previously recommended 10 MΩ input impedance is used in the amplifier. This distortion can lead to clinical misdiagnosis but can be avoided if the design constraints established in the paper are adopted.
CLIL AND GLOBAL EDUCATION: A MEANINGFUL MATCH

Education for future necessarily embraces multiple skills and themes which are transversal and applicable across the curriculum content. Students need to see and understand the content of individual subjects as connected and not as a discrete entity. CLIL as an approach which focuses on integration of meaningful context into a language learning classroom has been tested over the last decades and demonstrates that communication does not necessarily need to be limited to vocabulary and grammar practice. On the contrary as one of the global skills communication supports social interaction in problem solving, collaboration and thus is the key skill in achieving target goals. This study focuses on the readiness to implement the global skills within the CLIL approach among trainees in their last year of teacher training in Slovakia in 2019. The questionnaires and the subsequent interviews reveal that future language teachers still seem to prefer focusing on pure language aims to integrating global skills development and they even lack the confidence in application of transversal themes and skills. Even though there is a clear understanding of the importance of integration of global skills into education in general the lack of their own experience seems to determine their attitude towards them. These results identify the space for modification in the teacher training curriculum; however, it requires a wider cooperation within different subjects.
Abstract 5396: An NGS workflow to detect down to 0.1% allelic frequency in cfDNA for breast and colon cancers

Noninvasive detection of rare mutations in blood could allow tumor monitoring for research purposes. Research studies have suggested that cfDNA contains DNA from tumor cells with somatic mutations that could inform on tumor progression and therapeutic resistance. Here, we demonstrate a complete workflow from a single tube of blood through data analysis for research samples down to a 0.1% allelic frequency. The low abundance tumor mutations found in cfDNA requires sensitive and accurate mutation detection. We have developed two panels that utilize an amplification-based assay that generates tagged DNA copies, which allows detection of low abundance tumor mutations found in cfDNA. The two panels allow multiplex interrogation of primary driver and resistance mutations specific to ctDNA from breast and colon cancer. The Oncomine Colon cfDNA panel targets 236 hotspots within 14 genes while the Oncomine Breast cfDNA panel covers 157 hotspot mutations in 10 genes. This workflow was validated from matched single blood tubes, Streck and K2EDTA. Additionally, the utility for cancer research was demonstrated with concordance studies using matched FFPE and plasma from oncology samples. To further characterize these panels we have developed an oncology control for cfDNA with nucleosome fragment sizing and minimal sonication damage. This engineered control contains SNPs and indels at 0.1% allelic frequencies, orthogonally confirmed with TaqMan based Rare Mutation assays. With this control, the Oncomine Breast cfDNA panel had over 81% sensitivity and 99.9% specificity. The Oncomine Colon cfDNA panel had over 85% sensitivity and 100% specificity. The Oncomine Breast cfDNA panel and Oncomine Colon cfDNA panel integrated into a complete workflow starting from a single tube of blood can advance oncology research with the ability to detect blood based cancer biomarkers present at 0.1%. Citation Format: Dalia Dhingra, Richard Chien, Jian Gu, Dumitru Brinza, Ruchi Chaudhary, Kunal Banjara, Yanchun Li, Efren Ballesteros-Villagrana, Kelli Bramlett. An NGS workflow to detect down to 0.1% allelic frequency in cfDNA for breast and colon cancers [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5396. doi:10.1158/1538-7445.AM2017-5396