Miracle-dz/UniFAR-FTUs huggingface dataset:
Supplemental monensin affects growth, physiology, and coccidiosis infestation of early-weaned beef calves consuming warm-season perennial or cool-season annual grasses

ABSTRACT Objective Two experiments evaluated the effects of supplemental monensin on growth and physiology of early-weaned beef calves grazing ryegrass (Exp. 1) or bahiagrass (Exp. 2). Materials and Methods Brangus calves were weaned at 3 mo of age, stratified by sex and BW, and randomly assigned into 1 of 8 pastures (2 steers and 2 heifers per pasture per year) of ryegrass (Exp. 1; n = 2 yr) or bahiagrass (Exp. 2; n = 1 yr) from d 0 to 84. Treatments were assigned to pastures (4 pastures per treatment per year) and consisted of concentrate supplementation at 1 or 2% of BW (DM basis) in Exp. 1 and 2, respectively, with or without 20 mg of monensin/kg of DMI. Results and Discussion Herbage nutritive value and allowance did not differ (P ≥ 0.23) between treatments in Exp. 1 and 2, but herbage mass tended (P = 0.10) to increase by 5% for monensin versus control calves in Exp. 1. Calf overall ADG increased (P ≤ 0.005), whereas fecal coccidia egg count on d 84 decreased (P ≤ 0.0004), for monensin versus control calves in Exp. 1 and 2. Monensin supplementation tended (P ≤ 0.08) to increase plasma insulin concentrations in Exp. 1 and 2 and increased (P ≤ 0.03) plasma IGF-1 concentrations on d 56 in Exp. 1 and plasma urea nitrogen concentrations on d 84 in Exp. 2. Implications and Applications Supplemental monensin led to subtle changes to physiological parameters associated with energy metabolism, reduced coccidiosis infestation, and promoted the growth performance of early-weaned calves grazing ryegrass and bahiagrass pastures.
Risk Analysis of Depression, Sleep Hygiene Level and Chronic Disease with Insomnia in Elderly

The rapid progress of development in Indonesia have an impact on increasing life expectancy thus increasing the number of elderly. Elderly is the final stage of life so often experienced various changes and disturbances, one of which is a sleep disorder or Insomnia. The prevalence of insomnia in the elderly is quite high, more than 60% but the appearance of this disorder is often overlooked. This study was conducted observational case-control study design. Research sites in the Pelayanan Sosial Lanjut Usia Jombang and performed on 40 elderly people. The study population was divided into 2, 20 people population cases and 20 people population control. The variables studied were depression, chronic disease, sleep hygiene and Insomnia. Most of the elderly suffering from Subtreshold Insomnia with Difficulty Initiating Sleep symptoms are severe. Early Morning Awakening is the least symptom experienced by the elderly. Depression (OR = 22,667), chronic disease (OR = 6.926) and sleep hygiene (OR = 11,000) showed a significant association with Insomnia. The conclusion that can be drawn is perpetuating factors (chronic disease) and precipitating (sleep hygiene) plays a role in the emergence of insomnia in the elderly. The advice given is to take action to control chronic diseases and more attention on sleep disorders experienced by the elderly. In addition, the need for action to improve and enhance sleep hygiene. Keywords : depression, sleep hygiene, chronic disease, insomnia, elderly
Older People in Residential Care Settings

The National Centre for the Protection of Older People (NCPOP) hosted a report launch entitled ‘Older People in Residential Care Settings: Results of a National Survey of Staff-Resident Interactions and Conflicts’ on 6 December 2012. For full details on the report launch, including video presentations, full report, executive summary and presentation slides, please click on the following link http://www.ncpop. ie/httpwwwncpopie_staff_interactions.
In memoriam Prof. Dr. med. Dr. h. c. mult. Umberto Veronesi

Prof. Umberto Veronesi wurde am 28. November 1925 in Mailand geboren. Er studierte Medizin an der Universität in Mailand, wo er 1951 seinen Abschluss machte und seine Passion in der Mammachirurgie fand. Seine ersten internationalen Aufenthalte fanden in Frankreich (Lyon) und England (London) statt, bevor er an das Nationale Tumorinstitut in Mailand wechselte, dessen Direktor er 1975 wurde. Prof. Veronesi war 1965 Mitgründer der italienischen Krebsforschungsgesellschaft und gründete 1991 das weltbekannte European Institute of Oncology (IEO). Er war u. a. Präsident der Federation of European Cancer Societies (FECS), der Europäischen Gesellschaft für Tumorforschung (EORTC) und des Komitees der Krebsexperten der EU. Darüber hinaus setzte er sich als Mitgründer der Kampagnen „Europa gegen den Krebs“ und der europäischen Brustkrebsinitiative „Europa Donna“ für die Qualitätsstandards im Bereich Aufklärung, Diagnostik und Therapie des Mammakarzinoms auf europäischer Ebene ein.
Towards Probabilistic Timing Analysis for SDFGs on Tile Based Heterogeneous MPSoCs

Abstract—Performance and timing prediction of complex parallel data flow applications on multi-core systems is still a very difficult discipline. The reason for it comes from the complexity of the hardware platforms with difficult or hard to predict timing properties and the rising complexity of the software itself. In this work, we are proposing the combination of timing measurement and statistical simulation models for probabilistic timing and performance prediction of Synchronous Data Flow (SDF) applications on tile-based MPSoCs. We compare our work against mathematical and traditional simulation based performance prediction models. We have shown that the accuracy and execution time of our simulation can be suitable for design space exploration.
Role of black carbon in the formation of primary organic aerosols: Insights from molecular dynamics simulations

Abstract. Many studies on the mixing state of suspended particulate matters (PM) have pointed to the role of carbon particles as nucleation seeds in the formation of atmospheric aerosols. However, the underlying physicochemical mechanisms remain unclear, particularly concerning the involvement of volatile organic compounds (VOCs) at the primary stage of clustering. Here we gain insights into those microscopic formation mechanisms through molecular dynamics simulations of the physisorption of gaseous organic molecules on the surface of a carbon nanoparticle (NP). Six different organic species are selected among the VOCs dominating the atmospheric pollutants of several megacities, to interact with an onion-shell NP that mimics the primary soot particle. We consider organic molecules at various densities on the surface of a NP, as well as the same molecules in a freestanding configuration without any NP. The molecular clusters formed on the NP are found to be energetically more stable than those formed in the gas phase for all the six organic compounds. This points to a catalytic role of black carbon in the primary formation of aerosols from VOCs. Morphology analysis reveals different manners of clustering of aromatic and aliphatic compounds, which lead to different values of the binding energy and thus different thermal stability. Simulation results also suggest a layer-by-layer formation process of aerosol PM, consistent with previous transmission electron microscopy observations. These results shed light on the microscopic mechanisms of the primary formation of aerosol particulate matters, and are correlated with a variety of experimental measurements.
Analysis of Fiber, Calcium and Acceptability Cookies With Papaya Flour and Dates Puree Substitution

Background: Adolescent need adequate nutritious snack. Cookies is one of the best snack products, made from low protein and flourthan roasting until hard, cookies will taste crunchy when eaten. To make it more nutritious, papaya flour and dates puree is solution to increase dietary fiber and acceptability cookies. Objective: Analysing the effect of papaya flour and dates puree substitution in dietary fiber and acceptability of cookies. Methods: The type of research used complete randomized design with two repetitions. Making cookies using 4 formulation, there are control formulation papaya flour: dates puree, (PD1 10%: 30%), (PD2 20%: 20%) and (PD3 30%: 10%). The method used to determine dietary fiber content was multienzimatic method and acceptability was determined using hedonic test on colour, flavor, taste and texture by 90 panelist. Results: The highest total dietary fiber content was PD3 15.9g/100g. The acceptability cookies showed that panelists prefered cookies with PD2 formulation. Conclusion: Substitution with papaya flour and dates puree increased the level of dietary fiber cookies.Background: Adolescent need adequate nutritious snack. Cookies is one of the best snack products, made from low protein and flourthan roasting until hard, cookies will taste crunchy when eaten. To make it more nutritious, papaya flour and dates puree is solution to increase dietary fiber and acceptability cookies. Objective: Analysing the effect of papaya flour and dates puree substitution in dietary fiber and acceptability of cookies. Methods: The type of research used complete randomized design with two repetitions. Making cookies using 4 formulation, there are control formulation papaya flour: dates puree, (PD1 10%: 30%), (PD2 20%: 20%) and (PD3 30%: 10%). The method used to determine dietary fiber content was multienzimatic method and acceptability was determined using hedonic test on colour, flavor, taste and texture by 90 panelist. Results: The highest total dietary fiber content was PD3 15.9g/100g. The acceptability cookies showed that panelists prefered cookies with PD2 formulation. Conclusion: Substitution with papaya flour and dates puree increased the level of dietary fiber cookies.
CURRENT DEVELOPMENTS IN TRANSPORT MEDIA FOR AVULSED TEETH: AN UPDATE

Dental avulsion is one of the common types of trauma that results in the complete displacement of tooth from the alveolar socket. Although the ideal treatment would be the immediate reimplantation of the tooth at the site where the trauma took place, this may not be practically possible in every case. Hence, the avulsed tooth may have to be placed in an appropriate storage or transport medium until it is reimplanted. The biological properties of the storage medium have a significant impact on the success of reimplantation, as it must be capable of preserving the vitality, clonogenic, and mitogenic ability of the periodontal ligament cells for successful reimplantation.Keywords: Dental trauma, Avulsed teeth, Storage media, Periodontal ligament cell viability, Transport media.
Comparison of clinical and radiological outcomes after posterior acetabular fractures in patients younger and older than 40 years old

Aim: This study aimed to evaluate and compare the clinical and radiological outcomes of patients aged >40 years and ≤40 years old, who underwent open reduction internal fixation for posterior fracture and/or fracture dislocation of the acetabulum. Material and Methods: A total of 52 patients who underwent surgical treatment for posterior acetabular fracture and/or fracture dislocation between June 2006 and October 2013 were included in this study. The patients were divided into the following 2 groups: group I, patients aged <40 years (n = 25; mean age, 31.1; mean follow-up period, 35.7 months) and group II, patients aged >40 years (n = 27; mean age, 53.3; mean follow-up period, 36.8 months). The Judet–Letournel classification system was used in the radiological classification of acetabular fractures. Clinical and radiological evaluations were performed using the modified Merle D’Aubigne evaluation score and the criteria developed by Matta, respectively. In addition, radiological evaluation for heterotopic ossification was performed according to the Brooker scoring system. Results: No significant difference in the quality of reduction and clinical and radiological findings was found between the two groups (p>0.05). The modified Merle D’Aubigne clinical outcome distribution and the distribution of Matta radiological results in groups I and II did not differ significantly (p>0.05 and p>0.05, respectively). Moreover, no significant difference in the development of postoperative heterotopic ossification was observed between the groups (p>0.05). Conclusion: Clinical and radiological outcomes are not significantly different between patients younger and those older than 40 years. Nevertheless, the clinical outcome scores are better in patients aged ≤40 years.
Thirty years of personal experience in hyperglycemic crises: diabetic ketoacidosis and hyperglycemic hyperosmolar state.

CONTEXT Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) cause major morbidity and significant mortality in patients with diabetes mellitus. For more than 30 yr, our group, in a series of prospective, randomized clinical studies, has investigated the pathogenesis and evolving strategies of the treatment of hyperglycemic crises. This paper summarizes the results of these prospective studies on the management and pathophysiology of DKA. SETTING Our earliest studies evaluated the comparative efficacy of low-dose vs. pharmacological amounts of insulin and the use of low-dose therapy by various routes in adults and later in children. Subsequent studies evaluated phosphate and bicarbonate therapy, lipid metabolism, ketosis-prone type 2 patients, and use of rapid-acting insulin analogs as well as leptin status, cardiac risk factors, proinflammatory cytokines, and the mechanism of activation of T lymphocytes in hyperglycemic crises. MAIN OUTCOME The information garnered from these studies resulted in the creation of the 2001 American Diabetes Association (ADA) technical review on DKA and HHS as well as the ADA Position and Consensus Paper on the therapy for hyperglycemic crises. CONCLUSIONS Areas of future research include prospective randomized studies to do the following: 1) establish the efficacy of bicarbonate therapy in DKA for a pH less than 6.9; 2) establish the need for a bolus insulin dose in the initial therapy of DKA; 3) determine the pathophysiological mechanisms for the absence of ketosis in HHS; 4) investigate the reasons for elevated proinflammatory cytokines and cardiovascular risk factors; and 5) evaluate the efficacy and cost benefit of using sc regular insulin vs. more expensive insulin analogs on the general ward for the treatment of DKA.
No Improvement of Overall-Survival in Children with High-Risk Acute Myeloid Leukemia by Stem Cell Transplantation in 1st Complete Remission.

One aim of the AML-BFM 98 study was to evaluate prospectively the impact of matched sibling donor (MSD)-SCT in 1st complete remission (CR) in children with high-risk (HR)-AML. Patients: Between 7/1998 and 3/2004 494 children and adolescents were enrolled in the studies AML-BFM 98 and the AML-BFM 98 Interim 2003. Patients with favorable cytogenetics [t(8;21), inv(16), t(15;17)], corresponding morphology (AML FAB M1/2 with Auer rods, M4eo, M3) and Treatment: All patients received double induction and consolidation. MSD-SCT in 1st was scheduled after 4 blocs of treatment. Children who were not transplanted in 1st CR received intensification and a 1-year maintenance therapy. The recommended conditioning regimen consisted in busulfan and cyclophosphamide. Results ITT analysis revealed no significant differences in of 5 year disease-free survival (DFS) and overall survival (OS) between children with or without a donor (no donor vs. donor: DFS 43±4% vs. 47±7% plog rank 0.52; OS 56±4% vs. 58±9%, plog rank 0.16). The as-treated analysis gave similar results: CHT only vs. MSD-SCT: DFS 35±11% vs. 59±9% p Mantel-byar 0.13; OS 59±13% vs. 62±12%, p Mantel-byar 0.51). The major reasons of treatment failures were relapses in all groups [CHT only n=100 (52%), MSD-SCT n=13 (34%), MUD-SCT n=9 (50%)]. A 2nd CR was achieved in 71% of the CHT only group (n=74). After SCT in 2nd CR, OS was 40±6%. By contrast, only two children (9%) of 22 children after relapse following SCT in 1st CR could be salvaged. Severe late adverse events (e.g. severe chronic GvHD CTC grade IV, destruction of big joints, intracerebral bleedings) were more frequent in children transplanted in 1st CR (15%) than in those with CHT only (including SCT in 2nd CR; 5%, p×2 Conclusion: In the population-based, prospective multi-center study AML-BFM 98 allogeneic MSD-SCT in 1st CR showed no advantage in children and adolescents with HR-AML. Considering the higher toxicity of allogeneic SCT, in the ongoing trial AML-BFM 2004, this SCT (MSD or MUD) is restricted to patients in 2nd CR and refractory AML.
Lumbalgie bei Tänzern – Schwächere Muskelkontrolle in der lumbopelvinen Region

Sportverl Sportschaden 2013; 27 Bei einer chronischen Epikondylopathie führt die Injektion von Kortikosteroiden zu höheren Rezidivraten als Placebo. Dies ist das Ergebnis der randomisierten, vierarmigen, teilweise verblindeten Studie aus Australien. In die Studie wurden zwischen Juli 2008 und Mai 2010 insgesamt 165 Patienten, die seit mehr als 6 Wochen Beschwerden hatten, aus einer Klinik und 16 allgemeinmedizinischen Praxen aufgenommen. Die Patienten wurden randomisiert und im Hinblick auf die Art der Injektion verblindet auf folgende Behandlungsmaßnahmen verteilt: 3 Kortikosteroidinjektion (n = 43) 3 Placeboinjektion (0,9 %ige Kochsalzlösung; n = 41) 3 Kortikosteroidinjektion plus Physiotherapie (n = 40) 3 Placeboinjektion plus Physiotherapie (n = 41)
Head and Neck Cancer - Bangladesh Perspective

Human body contains about 100 trillion cells. There are 200 types of cells and 100 types of cancer are detected there. Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. It attacks like a crab with multiple claws and try to kill the victims. Cancer is number 2 killer and 1 death is among 6 death according to IARC (International agency for research on cancer).
‘Hayi, they don’t know Xhosa’: Comparative isiXhosa teaching challenges in the Eastern Cape and Gauteng

Language-in-education policy in South Africa is underpinned by the Constitution. The gap that this research addresses is the inconsistency of policy implementation and the actual teaching of isiXhosa in primary schools. It analyses the official and overt language policy and the (covert) language practices at schools. Semi-structured interviews were conducted with language teachers and principals. Data were also gathered from classroom observations and document analysis in the Eastern Cape and Gauteng. On the one hand, there are standard language policy documents that exist. These advocate for English as a language of learning and teaching and isiXhosa as a subject. On the other hand, the daily reality in classrooms partly reflects this policy implementation. Furthermore, we conclude that there is no consistency in the teaching of isiXhosa home language, as well as First and Second Additional Language. There is insufficient teaching material and teachers are not capacitated in terms of pedagogical training in multilingual settings.
Host-rock deformation during the emplacement of the Mourne Mountains granite pluton: Insights from the regional fracture pattern

The Mourne Mountains magmatic center in Northern Ireland consists of five successively intruded granites emplaced in the upper crust. The Mourne granite pluton has classically been viewed as a type locality of a magma body emplaced by cauldron subsidence. Cauldron subsidence makes space for magma through the emplacement of ring dikes and floor subsidence. However, the Mourne granites were more recently re-interpreted as laccoliths and bysmaliths. Laccolith intrusions form by inflation and dome their host rock. Here we perform a detailed study of the deformation in the host rock to the Mourne granite pluton in order to test its emplacement mechanism. We use the host-rock fracture pattern as a passive marker and microstructures in the contact-metamorphic aureole to constrain large-scale magma emplacement-related deformation. The dip and azimuth of the fractures are very consistent on the roof of the intrusion and can be separated into four steeply inclined sets dominantly striking SE, S, NE, and E, which rules out pluton-wide doming. In contrast, fracture orientations in the northeastern wall to the granites suggest shear parallel to the contact. Additionally, contact-metamorphic segregations along the northeastern contact are brecciated. Based on the host-rock fracture pattern, the contact aureole deformation, and the north-eastward–inclined granite-granite contacts, we propose that mechanisms involving either asymmetric “trap-door” floor subsidence or laccolith and bysmalith intrusion along an inclined or curved floor accommodated the emplacement of the granites and led to deflection of the northeastern wall of the intrusion.
Usulan Perbaikan Sistem Customer Relationship Management (CRM) CV. XYZ Berdasarkan Pertimbangan ISO 9001:2015 Klausul 8.2.1 dengan Metode Business Process Improvement

CV. XYZ adalah salah satu produsen sandal gunung travelling handmade yang berdomisili di Bandung. Agar dapat bersaing di pasar, CV. XYZ harus selalu memperhatikan kualitasnya dari segi produk dan juga layanan. Pada saat ini CV. XYZ sudah menerapkan Customer Relationship Management (CRM) sebagai upaya untuk menjaga loyalitas pelanggan. Sosial media digunakan sebagai penunjang CRM yang termasuk ke dalam Customer Interface Management yang mengacu pada pengelolaan pertukaran informasi. Meskipun sistem CRM sudah terlaksana, namun belum semua terlaksana dengan baik sesuai dengan konseptual yang ada. Pada penelitian ini, digunakan pertimbangan persyaratan ISO 9001:2015 klausul 8.2. 1 komunikasi pelanggan dan konsep CRM untuk mendapatkan hasil analisis Gap yang baik dan lengkap. Metode yang digunakan yaitu business process improvement dengan menggunakan langkah apply techniques improvement. Hasil dari penelitian ini adalah rancangan untuk merealisasikan produk custom dan juga beberapa perbaikan seperti pembuatan database dan penambahan opsi pada website.
HPV-Infektionen: Diagnostik und Impfung

Humane Papillomaviren (HPV) sind doppelsträngige DNA-Viren, von denen > 200 verschiedene Subtypen bekannt sind. Die HPV-Subtypen lassen sich je nach malignem Potenzial einer Infektion entweder in Niedrigrisikosubtypen (6, 11, 40, 42, 43, 44, etc.) oder Hochrisikosubtypen (6, 18, 31, 33, 35, 39 etc.) einteilen. Die häufigsten Hochrisikosubtypen sind HPV 16 und 18 (verantwortlich für 70% der Zervixkarzinome) [1]. Die Infektion mit HPV-Niedrigrisikosubtypen kann zu gutartigen Feigwarzen oder Larynxpapillomatose führen, während eine Infektion mit Hochrisikosubtypen zu invasiven Karzinomen insbesondere dem Zervixkarzinom, aber auch Karzinomen des Mund-Rachen-Raums, Vagina-, Vulva-, Penisund Analkarzinomen führen kann [2].
Conservation, Conflict, and Community Context: Insights from Indian Tiger Reserves

Throughout India, tiger-centric wildlife tourism is often viewed as a way to support human livelihoods and encourage positive attitudes towards conservation. But this approach only works if local communities participate in the tourism economy and embrace it as a strategy for promoting both development and conservation. We examined differences in community perceptions towards tourism using a mixed-methods, comparative case study design in two distinct Indian national parks (Ranthambore National Park, Rajasthan; Dudhwa National Park, Uttar Pradesh). While both parks are important tiger habitats, Ranthambore (RNP) is one of India’s most iconic wildlife tourism destinations and Dudhwa (DNP) is just beginning to attract tourists. We focused on three key metrics: 1) knowledge and awareness of tourism 2) beliefs about tourism’s impact on communities, and 3) beliefs about tourism’s impact on parks and wildlife. Data were collected from June to August 2018 at both sites through community surveys (n=193 in RNP, n=114 in DNP) and semi-structured interviews with community leaders and key informants (N=15 in RNP, 15=DNP). Awareness of tourism and employment in the tourism industry was low at both sites, and particularly low at DNP. Beliefs about the economic impacts of tourism were positive in tourism zones, where villages had more