Miracle-dz/UniFAR-FTUs huggingface dataset:
Detecting Positioning Errors and Estimating Correct Positions by Moving Window

In recent times, improvements in smart mobile devices have led to new functionalities related to their embedded positioning abilities. Many related applications that use positioning data have been introduced and are widely being used. However, the positioning data acquired by such devices are prone to erroneous values caused by environmental factors. In this research, a detection algorithm is implemented to detect erroneous data over a continuous positioning data set with several options. Our algorithm is based on a moving window for speed values derived by consecutive positioning data. Both the moving average of the speed and standard deviation in a moving window compose a moving significant interval at a given time, which is utilized to detect erroneous positioning data along with other parameters by checking the newly obtained speed value. In order to fulfill the designated operation, we need to examine the physical parameters and also determine the parameters for the moving windows. Along with the detection of erroneous speed data, estimations of correct positioning are presented. The proposed algorithm first estimates the speed, and then the correct positions. In addition, it removes the effect of errors on the moving window statistics in order to maintain accuracy. Experimental verifications based on our algorithm are presented in various ways. We hope that our approach can help other researchers with regard to positioning applications and human mobility research.
Pneumococci with increased resistance to penicillin.

SIR,-The comparative passivity with which the profession stood by and watched the banning of cyclamates in Great Britain makes your leading article (28 July, p. 185) both timely and important. It would appear (as many of us suspected) that there are now as good-or one sihould rather say as inadequate-grounds for banning saccharin as there was for banning cyclamates. Your article reminds us that so far neither ban is justified. If there be those in Britain who wish to force the unwarranted requirements of the United States Delaney Clause on us they would do well to consider that on the evidence at present available it would undoubtedly be preferable for us to use saccharin and indeed cyclamates rather than sugar whenever that is possible. Since no one else has bothered to do so I hereby take it upon myself to call for the repeal of the entirely unnecessary ban on cyclamates. -I am, etc.,
Endocytosis of Insulin-like Growth Factor II by a Mini-receptor Based on Repeat 11 of the Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor*

The mannose 6-phosphate/insulin-like growth factor II receptor (M6P/IGF-II receptor) plays an important role in controlling the extracellular level of the insulin-like growth factor II (IGF-II) by mediating its binding at the cell surface and delivery to lysosomes. Loss of the receptor is associated with an accumulation of IGF-II, which can cause perinatal lethality if it is systemic, or local proliferation and tumorgenesis if it is spatially restricted. The extracytoplasmic domain of the receptor consists of 15 homologous repeats, of which repeat 11 carries the IGF-II-binding site of the multifunctional receptor. To investigate whether repeat 11 is sufficient to mediate binding and internalization of IGF-II, a construct consisting of repeat 11 fused to the transmembrane and cytoplasmic domain of the M6P/IGF-II receptor was transfected into mouse embryonic fibroblasts. The construct was expressed as a stable membrane protein which binds IGF-II with a 10-fold lower affinity as observed for the M6P/IGF-II receptor and is found at the cell surface and in endosomes. It mediates the internalization of IGF-II and its delivery to lysosomes, suggesting that it can function as a IGF-II mini-receptor controlling the extracellular IGF-II level.
Agile Methods and Requirements Engineering in Change Intensive Projects

In this paper we discuss how well agile methods can deal with requirements related issues in change intensive projects. Five agile methods are considered: eXtreme Programming, Scrum, Crystal, Dynamic Systems Development Method and Adaptive Software Development. We analyze how well these methods implement the basic goals of requirements engineering, how they counteract or support the occurrence of requirements changes and how they cope with problems arising from changing requirements. We show that agile methods provide a valid approach for requirements related issues, but also identify their weaknesses.
Multiple cycles of high dose chemotherapy supported by hematopoietic progenitor cells as treatment for patients with advanced malignancies

Background. Retrospective studies suggest that dose intensity is an important determinant of outcome in the treatment of patients with a variety of malignant diseases such as breast cancer, ovarian cancer, and lymphoma. Unfortunately, these results have not been clearly substantiated in prospective randomized trials. One problem with these studies may be that the degree of dose escalation is not sufficient to result in an improved outcome because the chemotherapy doses are limited by hematopoietic toxicity. In an attempt to deliver more dose‐intensive therapy, the feasibility of the administration of multiple cycles of high dose chemotherapy with hematopoietic progenitor cell and growth factor support was investigated in patients with advanced malignancies.
Depth video based human model reconstruction resolving self-occlusion

Generation of a 3D model has been actively researched in computer vision area. Especially, modeling of a realistic human is a topic of great interest due to its use in many application areas such as animation and 3DTV. In this paper, a novel method is presented to generate a 3D human model using a sequence of depth images from a monocular TOF (time-of-flight) camera. Mainly, we solve a 'self-occlusion' problem which occurs in the depth data where a human model is partially occluded by other parts of a human body. This becomes very critical when we want to develop a human model for various applications. We demonstrate the capability of our method by showing experimental results that resolves a multiple occlusion problem.
Molecular dynamics simulations of early steps in RNA‐mediated conversion of prions

The rate‐limiting step in prion diseases is the initial transition of a prion protein from its native form into a mis‐folded state in which the protein not only forms cell‐toxic aggregates but also becomes infectious. Recent experiments implicate polyadenosine RNA as a possible agent for generating the initial seed. In order to understand the mechanism of RNA‐mediated mis‐folding and aggregation of prions, we dock polyadenosine RNA to mouse and human prion models. Changes in stability and secondary structure of the prions upon binding to polyadenosine RNA are evaluated by comparing molecular dynamics simulations of these complexes with that of the unbound prions.
Black-box expensive multiobjective optimization with adaptive in-fill rules

To deal with real-life black-box expensive multiobjective optimization problems, we investigated the application of an optimization framework expanded from MOEA/D-EGO. As MOEA/D-EGO, Gaussian process modeling techniques are used to subtittute the evaluation of the problem itself. Apart from the expected improvement (EI) in-fill rule in the original MOEA/D-EGO, we define a process that adaptively selects of in-fill rule in each iteration from seven different in-fill rules, including confidence limit of different probability (CLp), probability of improvement (PI), and EI. The initial probabilities of selecting a specific in-fill rule are derived from applying the algorithm on ZDT test suite. The practical problem set-up and optimization results and lesson learned in the process are reported.
A functional polymorphism C‐1310G in the promoter region of Ku70/XRCC6 is associated with risk of renal cell carcinoma

The DNA repair gene Ku70 plays a key role in the DNA double strand break (DSB) repair system. Defects in DSB repair capacity can lead to genomic instability. We hypothesized that the Ku70 C‐1310G polymorphism (rs2267437) was associated with risk of renal cell carcinoma (RCC). We genotyped the Ku70 C‐1310G polymorphism in a case–control study of 620 patients and 623 controls in a Chinese population and assessed the effects of C‐1310G polymorphism on RCC susceptibility and survival. We then examined the functionality of this polymorphism. Compared with the Ku70‐1310CC genotype, the CG and CG/GG genotypes had a significantly increased risk of RCC [adjusted odds ratio (OR) = 1.47, 95% confidence interval (CI) = 1.16–1.87 for CG and OR = 1.47, 95% CI = 1.16–1.86 for CG/GG]. However, the C‐1310G polymorphism did not influence the survival of RCC. The in vivo experiments with normal renal tissues revealed statistically significantly lower Ku70 mRNA expression in samples with CG/GG genotypes relative to those with the CC genotype (P < 0.05). In vitro luciferase assays in various cell lines showed lower luciferase activity for the −1310G allele than for the −1310C allele. These results suggest that the Ku70 C‐1310G polymorphism is involved in the etiology of RCC and thus may be a marker for genetic susceptibility to RCC in Chinese populations. Larger studies are warranted to validate our findings. © 2012 Wiley Periodicals, Inc.
Inpatient Management of Guillain-Barré Syndrome

Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis in the developed world. Guillain-Barré syndrome typically presents with ascending paralysis and is usually severe enough to warrant hospital admission for management. In the United States alone, GBS results in more than 6000 hospitalizations each year. Although GBS patients were historically cared for at tertiary referral centers, changing treatment practices have broadened the number of neurologists who care for the disease. This article provides a review of key issues in the inpatient management of GBS. A survey of the evidence base for treatment with plasma exchange or intravenous immunoglobulins is presented. Although either of these treatments can limit the severity of GBS, patients are still at risk for a broad range of complications, including respiratory failure, autonomic dysfunction, thromboembolic disease, pain, and psychiatric disorders. Awareness of these complications, their detection and management, may help limit the morbidity of GBS.
Vessels for the ancestors : essays on the Neolithic of Britain and Ireland in honour of Audrey Henshall

A team of British and Irish prehistorians present this work on the Neolithic. They concentrate specifically on the sites in the North and West of Britain and Ireland - areas which seem to have been glossed over in previous studies. Traditional scholarly presentations are combined with applied theoretical approaches, and there is an emphasis on providing new material to support the theories. The book is divided into four main sections - funerary studies, decorated stones, artefact studies and regional studies. In each section there are new insights into material which has been studied for years as well as a summary of the latest research in the area. There is a discussion of the problems facing Neolithic archaeologists in the region and an analysis of the way forward for future research. Contributors include Richard Bradley, Roger Mercer and George Eogan, and the book should be useful to anyone studying British and Irish prehistory.
Turbo1500: Toward Core-Based Design for Test and Diagnosis Using the IEEE 1500 Standard

This paper describes a core-based test and diagnosis integration and automation system, called Turbo1500, which automatically synthesizes test and diagnosis logic in accordance with the IEEE 1500 standard. Turbo1500 serves two major purposes. One is for use as a core test automation tool in a system-on-chip (SOC) environment to automatically connect multiple cores from various sources and create testbenches each targeting an individual core under the control of a chip-level test access port (TAP) controller. The other is for hierarchical (block-by-block) core test and diagnosis when chips on a printed-circuit board are embedded with 1149.1 boundary scan I/O cells and cores under test and diagnosis are surrounded with 1500-compliant wrapper cells. Application experience showed that the simplicity of the IEEE 1500 standard combined with an easy-to-use automation tool can make core-based design for test and diagnosis no longer a nightmare, especially when some cores are extremely large or complex.
Black and White Colobus Monkey (Colobus guereza) Roars as a Source of Both Honest and Exaggerated Information About Body Mass

Formant dispersion, the average spacing, in Hz, between the resonant frequencies of a vocalization, has been predicted to provide honest information about signaler body size. Previous descriptions of black and white colobus monkey (Colobus guereza, ‘‘guereza’’) roars, however, suggest a formant dispersion that is far lower than expected for an animal its size, and could effectively exaggerate its body size. Nonetheless, recent research on red deer shows that even when the formant positions of vocalizations effectively exaggerate body size, they may still provide honest cues within a species. We investigate whether the frequency bands observed in the spectrograms of guereza roars represent formants, and whether roar formant dispersion and/or individual formants provide honest information about body size (specifically, body mass) relative to conspecifics, although perhaps not relative to other species. We document coordinated vertical movements in the frequency bands of guereza roars and show that these bands move independently of fundamental frequency, indicating that they represent formants. We show, for captive adult male guerezas, that signaler body mass significantly predicts roar formant dispersion, even for randomly selected calls. Body mass also predicts formants 2 and 3, but the relationships are not as strong as with formant dispersion. Our roar formant dispersion calculations predict a vocal tract length of approx. 29 cm, but anatomically determined guereza vocal tract length is much smaller: approx. 7–8 cm. Videotaped roars revealed no laryngeal movement during roars, but rather inflation of the subhyoid air sac. We measured the volume of this air sac (approx. 10 cm 3 ) and speculate that it may function in roars to exaggerate body size, relative to other species.
Cloud computing based high-performance platform in enabling scalable services in power system

This paper discusses the characteristics of the cloud computing techniques and further compares the features of the cloud computing to those of the traditional distributed computing. The paper also studies the types and forms of the modern services and requirements in power systems, and therefore aiming at designing and constructing a high-performance platform in enabling scalable power system services based on cloud computing is presented. The details of the platform design including data distribution, process monitoring, data integration and resource scheduling have been fully presented. The application of the platform in a practical power system indicates that it can significantly simplify the design, development and implementation of the power system computing services and systems, which improves the efficiency of the daily services of power system.
Valor pronóstico de la coexpresión de los receptores de crecimiento epidérmico EGFR y c-erbB-2 en el carcinoma localmente avanzado de cérvix

El carcinoma de cervix engloba un grupo complejo de tumores cuyo comportamiento no es uniforme en cuanto a su evolucion clinica ni a la respuesta a los diversos tratamientos. En los ultimos anos se han desarrollado avances en el diagnostico precoz del cancer de cervix a partir de la citologia cervico-vaginal, y en el tratamiento de los carcinomas avanzados mediante el uso concomitante de quimioterapia y radioterapia. Aun asi, el cancer de cervix continua siendo el tumor mas frecuente y la primera causa de mortalidad por cancer en las mujeres de paises con un mal desarrollo socio-economico e higienico. Alrededor del 50% de las enfermas diagnosticadas de un carcinoma invasivo de cervix falleceran debido a la aparicion de recidivas locales del tumor o por metastasis a distancia. Nuestro trabajo es el primero que estudia el impacto pronostico de la coexpresion de EGFR y c-erbB-2 en la supevivencia libre de enfermedad y en la supervivencia libre de fracaso pelvico en pacientes diagnosticadas de carcinoma de cervix con estadios localmente avanzados no operadas, y tratadas con quimioterapia y radioterapia concurrente. La identificacion de subgrupos de pacientes con una peor evolucion clinica es crucial a la hora de proponer y estudiar nuevos enfoques terapeuticos que actuan sobre moleculas involucradas en las vias de transduccion de senales del EGFR.
Ultra low leakage 90nm content addressable memory design for wireless sensor network applications

Wireless sensor networks are emerging as a compelling solution for a diverse range of data gathering applications. The constituent sensor nodes in these networks typically run on unreplenishable battery supplies, thereby placing energy at a premium. Ultra-low power content addressable memory is required to implement the routing caches for many network protocols used in wireless sensor networks. This paper investigates several circuit techniques for reducing leakage currents in content addressable memories on a 90nm process. Simulations show that leakage currents in a 4kbit memory array can by reduced by a factor of 168x relative to a conventional, unoptimized design.
What's in an Alias? Family Names, Individual Histories, and Historical Method in the Western Sudan

Writing in his Les Bambara du Ségou et du Kaarta, the French colonial administrator and ethnographer Charles Monteil considered the family name, or jamu, to sum up the history of the community which bears it: it refers to everything which concerns the ancestors, as well as the accomplishments of current members of the community, including their turpitudes and even their alliances, be they fraternal, conjugal, political, or supernatural. Monteil was right, to a certain degree. In the Western Sudan, family names are weighted with history and significance. Yet what Monteil characterized as evidence of stability and tradition, Charles Bird has more recently called a “ticket to mobility. ” The fluidity and mobility that had come to characterize the jamu eluded Monteil entirely, just as its mutability often eludes contemporary historians. A jamu represents both an all-important identity marker and an instrument of “mobility. ” Yet it is also highly contigent, even aleatory. This mobility has a double sense, signifying both the mutable nature of the name itself and its potential for “making outsiders insiders” by creating an immediate link between people who would otherwise be strangers. Jamuw—the plural takes a ‘w’—also have a deep historicity. Embedded in them are history and myth, along with suggestions of family occupational category—commonly referred to as ‘caste’—and social status. Epics such as Sundiata often provide etymologies and legendary origins of family names, and scholars have sought—misguidedly—to use these to understand the historical processes of ‘caste’ formation and other aspects of the distant Mande past.
Psychometric characteristics of Duruoz Hand Index in patients with traumatic hand flexor tendon injuries

Introduction. The aim of the study was to assess reliability, validity and responsiveness of Duruoz Hand Index (DHI), which has been developed for evaluation of activity limitation in rheumatoid arthritis in patients with traumatic hand flexor tendon injuries. Material and method. Sixty-five patients older than 16 years who underwent surgical intervention after flexor tendon injuries were enrolled. Reliability was assessed by internal consistency (with Cronbach's-α) and test-retest intraclass correlation coefficient (ICC). Construct validity was estimated correlating the scale with the DASH and VAS-hd. Also responsiveness was estimated using standardised response mean (SRM) and effect size (ES). Result. Mean age of the patients was 30.25 ± 11.07 years and totally 140 fingers were evaluated. Cronbach's-α and ICC values of DHI were found to be 0.87 and 0.99, respectively. In validation study, highly significant correlation was detected between DHI with DASH and VAS-hd (r == 0.86, r == 0.54, p < 0.0001, respectively). SRM values and ES values (excepting workplaces subgroup score) were higher than 0.80 for total and all subgroup scores. Conclusion. DHI is a reliable, valid questionnaire to assess hand-related activity limitation in patients with traumatic hand flexor tendon injuries. Also, due to its high level responsiveness DHI can be used for assessing the clinical course of the traumatic hand flexor tendon injured patient.
The Experimental Hydration of Obsidian as a Function of Relative Humidity and Temperature

The experimental hydration of obsidian for up to 30 days is described at relative humidities (RH) of 60, 90, 95, and 100 percent and at temperatures of 150, 160, and 175°C. Under isothermal conditions, the rate of hydration increased by as much as 25 percent between 60 and 100 percent RH. The RH dependence is nonlinear, with the majority of the rate increase occurring between 90 and 100 percent RH. The effect of RH can be related to the driving force for molecular water diffusion in obsidians as described by the chemical potential difference between water sorbed onto the obsidian surface and intrinsic water in the obsidian. The differences in hydration rates caused by RH differences in experiments approximate the error commonly described for obsidian-hydration dating. These results suggest that obsidian-hydration dating requires a knowledge of the site temperature and relative humidity in order to accurately generate age estimates.
Design of a Flux-Shunt Permanent Magnet DC Motor With Hybrid Magnetomotive Force and Anti-Demagnetization Property

Rare-earth magnets of high-energy products have been widely used to improve the efficiency, as well as the power and torque per unit weight, of permanent-magnet machines. In addition to the drawbacks of limited resources and high prices, the rare-earth magnet may risk irreversible demagnetization during field weakening or malfunctioning in machine operation. To solve this problem, we investigate the antidemagnetization property due to the flux shunt mechanism and hybrid magnetomotive force in a permanent-magnet direct-current motor. The hybrid magnetomotive force is provided by low-grade permanent magnets and additional field windings, between which are ferromagnetic media that shunt the adjustable magnetic flux in the machine. We performed an optimal machine design and verified it with a finite-element analysis. We fabricated a prototype, and the experimental results show that machine efficiency and torque are increased by increasing the current of the field winding and that machine speed can be extended by reducing the field current. Finally, we proved that the antidemagnetization mechanism is effective by investigating the reduction of back electromagnetic force after demagnetization.
Effect of phototherapy on the plasma bilirubin concentration of newborn foals

BILIRUBIN excretion is inefficient in neonatal mammals because the hepatic conjugating system and biliary excretion are still immature ([Cashore 2004][1]). This leads to neonates undergoing different degrees of physiological hyperbilirubinaemia ([Johnson and others 2002][2]). Persistent severe