Miracle-dz/UniFAR-FTUs huggingface dataset:
Theoretical and experimental Investigation of Structural, electronic and optical properties of neodymium doped ZnO

The morphological and cathodoluminescent properties of Nd doped zinc oxide thin films deposited by reactive chemical pulverization spray pyrolysis technique on heated glass substrates at 450 °C are being reported. The films were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and cathodoluminescent (CL) spectroscopy. We have also used the Generalised Gradient Approximation (GGA)-the Self Interaction Corrected (SIC) to determine Electronic structure and x ray absorption.
Endocytosis frustration potentiates compression-induced receptor signaling

Cells experience mechanical stresses in different physiological and pathological settings. Clathrin-coated structures (CCSs) are sensitive to such perturbations in a way that often results in a mechanical impairment of their capacity to bud, ultimately impairing endocytosis. Compressive stress is a particular mechanical perturbation that leads to increased membrane tension and promotes proliferative signals. Here, we report that compression leads to CCSs frustration and that CCSs are required to potentiate receptor-mediated signaling in these conditions. We first confirmed that pressure stalls CCSs dynamics and showed that it also slows down the dynamic exchange of CCSs building blocks. As previously reported, compression-induced paracrine activation of the epidermal growth factor receptor (EGFR) was the primary cause of ERK activation in these conditions. We observed that the EGFR was efficiently recruited at CCSs upon compression and that CCSs were required for full ERK activation. In addition, we demonstrated that compression-induced frustrated CCSs could also serve as signaling platforms for the hepatocyte growth factor receptor (HGFR), provided HGF was present in the medium. We thus propose that, besides the particular case of EGFR paracrine activation, CCS frustration resulting from mechanical perturbations can potentiate signaling through different receptors with potential important consequences on cell adaptation to its environment.
The Original Anisotropy of TeV Cosmic Rays in the Local Interstellar Medium

This paper presents the original anisotropy that TeV cosmic rays (CRs) have in the local interstellar medium. This anisotropy is obtained using a method of flux mapping with the Liouville theorem and a magnetohydrodynamic (MHD) heliosphere model of the electromagnetic field to remove the particle propagation effects hidden in the measurements made by the Tibet ASγ experiment at Earth. The original interstellar anisotropy turns out to be almost a pure dipole, which results from a diffusion flow of CRs escaping along the local interstellar magnetic field into the northern Galactic halo. The observed anisotropy maps at Earth appear quite complex because the heliosphere distorts the dipole anisotropy, generating a significant amount of high-order multipoles, while interstellar magnetic field fluctuations contribute to some weak anisotropy on small angular scales. It is found that the density gradient of these CRs points approximately toward Vela in the Local Bubble, providing experimental evidence to show that the local supernova is making a special contribution to the TeV CRs we see at Earth. This special contribution will keep growing in the future tens of thousand years. The original anisotropy also reveals that the CRs spread from the source primarily along the interstellar magnetic field, while experiencing a nearly isotropic pitch-angle scattering process caused by interstellar turbulence.
Forecasting Mood in Bipolar Disorder From Smartphone Self-assessments: Hierarchical Bayesian Approach

Background Bipolar disorder is a prevalent mental health condition that is imposing significant burden on society. Accurate forecasting of symptom scores can be used to improve disease monitoring, enable early intervention, and eventually help prevent costly hospitalizations. Although several studies have examined the use of smartphone data to detect mood, only few studies deal with forecasting mood for one or more days. Objective This study aimed to examine the feasibility of forecasting daily subjective mood scores based on daily self-assessments collected from patients with bipolar disorder via a smartphone-based system in a randomized clinical trial. Methods We applied hierarchical Bayesian regression models, a multi-task learning method, to account for individual differences and forecast mood for up to seven days based on 15,975 smartphone self-assessments from 84 patients with bipolar disorder participating in a randomized clinical trial. We reported the results of two time-series cross-validation 1-day forecast experiments corresponding to two different real-world scenarios and compared the outcomes with commonly used baseline methods. We then applied the best model to evaluate a 7-day forecast. Results The best performing model used a history of 4 days of self-assessment to predict future mood scores with historical mood being the most important predictor variable. The proposed hierarchical Bayesian regression model outperformed pooled and separate models in a 1-day forecast time-series cross-validation experiment and achieved the predicted metrics, R2=0.51 and root mean squared error of 0.32, for mood scores on a scale of −3 to 3. When increasing the forecast horizon, forecast errors also increased and the forecast regressed toward the mean of data distribution. Conclusions Our proposed method can forecast mood for several days with low error compared with common baseline methods. The applicability of a mood forecast in the clinical treatment of bipolar disorder has also been discussed.
Distribution of congenital malformations at birth in a tertiary care hospital in North-Western Rajasthan

Background: A significant number of neonates are born with congenital anomalies. It is one of the leading cause of neonatal/infant mortality worldwide. The morbidity and disability experienced by surviving children and their parents also has major public health impact. This study was planned to find incidence of such birth defects and their system wise distribution. Methods: This was an observational prospective study during one year period from Jan 2012 to Dec 2012 in Dept. of Obstetrics and Gynecology, PBM Medical college Hospital, Bikaner (Rajasthan). Results: Out of total 13,614 consecutive live/still births, 167 neonates were found to have congenital malformations. The overall incidence being 1.23% (12.3/1000 births). Commonest (53.3%) anomalies were of CNS followed by other systems. Conclusions: This study was an effort to find frequency and distribution pattern of congenital malformations at birth in a tertiary care centre of North –Western Rajasthan. CNS was found to be the commonest site of such defects followed by cleft lip and palate and others.
Unilateral sudden sensorineural hearing loss after combined spinal-epidural anesthesia for emergency cesarean section -A case report-

A 30-year-old primigravida with gestational age of 25 weeks and 4 days was admitted for emergency cesarean section. She was diagnosed as pre-eclampsia with fetal distress. We anesthetized the patient through the combined spinal-epidural anesthetic technique, and there was no specific event throughout the surgical procedures and in post anesthetic care unit. Subsequently, she complained of unilateral hearing difficulty in the ward and an otolaryngology consultation was obtained. She was diagnosed with left sudden sensorineural hearing loss in full frequency range after an acoustic examination. She received intravenous and local steroid treatments for 4 weeks. She showed 32 dB on pure tone audiometry after 5 months. However, we could not continue follow-up testing on the patient because she stopped visiting the hospital since the last examination. We reported a case of uncommon unilateral sudden sensorineural hearing loss after a combined spinal-epidural anesthesia for emergency cesarean section. (Anesth Pain Med 2016; 11: 359-361)
Preliminary Evaluation of Hepatoprotective Activity of Trianthema portulacastrum Linn

Objective : To study hepatoprotective effect of aerial parts of Trianthema portulacastrum . Materials and methods : Hepatoprotective activity of T. portulacastrum was evaluated using paracetamol and rifampicin as liver toxicants in rats. The potency of alcoholic and aqueous extracts of aerial parts was compared with that of silymarin at a dose of 100 mg/kg, P.O. The SGOT, SGPT and bilirubin levels of blood were measured spectrophotometrically. Results : Alcoholic extract of aerial parts caused significant fall in the enzyme levels in serum in rats. Conclusion : T. portulacastrum has shown significant activity in rats toxicated with paracetamol and rifampicin and can be recommended for further studies.
Measuring emotional problems in Turkish adolescents: Development and initial validation of the Youth Internalizing Behavior Screener

ABSTRACT The present study reports on the preliminary development and validation of the Youth Internalizing Behavior Screener (YIBS) aimed at assessing internalizing behavior problems in Turkish adolescents. Participants of the study included two independent samples, comprising of 420 adolescents from two public high schools in an urban city of Turkey. Exploratory factor analysis results (N = 217) indicated that the YIBS provided a two–factor latent construct, which comprised of 10 items, with equal items targeting core symptoms of both depression and anxiety disorders. Subsequently, confirmatory factor analysis (N = 203) confirmed the two-factor measurement model and provided good data-model fit statistics. All scales had adequate–to–strong latent construct (H range = .84–.92) and internal reliability estimates (α range = .75–to–.90). Validity analyzes also provided further evidence, demonstrating the small–to–large relationships between the YIBS and criterion variables (e.g., subjective wellbeing, conduct problems, peer problems). Latent variables path model indicated that measurement models had moderate–to–large predictive effects on youth school functioning and wellbeing indicators. Overall, these results suggest that the YIBS may be useful to identify Turkish adolescents with elevated levels of internalizing behavior problems and concurrently poor educational and wellbeing outcomes, providing a warrant for prevention and intervention in school settings.
Relationships Among Bone Morphological Parameters and Mechanical Properties of Cadaveric Human Vertebral Cancellous Bone

Mechanical properties and morphological features of the vertebral cancellous bone are related to resistance to fracture and capability of withstanding surgical treatments. In particular, vertebral strength is related to its elastic properties, whereas the ease of fluid motion, related to the success of incorporation orthopedic materials (eg, bone cement), is regulated by the hydraulic permeability (K). It has been shown that both elastic modulus and permeability of a material are affected by its morphology. The objective of this study was to establish relations between local values of K and the aggregate modulus (H), and parameters descriptive of the bone morphology. We hypothesized that multivariate statistical models, by including the contribution of several morphology parameters at once, would provide a strong correlation with K and H of the vertebral cancellous bone. Hence, μCT scans of human lumbar vertebra were used to determine a set of bone morphology descriptors. Subsequently, indentation tests on the bone samples were conducted to determine local values of K and H. Finally, a multivariate approach supported by principal component analysis was adopted to develop predictive statistical models of bone permeability and aggregate modulus as a function of bone morphology descriptors. It was found that linear combinations of bone volume fraction, trabecular thickness, trabecular spacing, structure model index, connectivity density, and degree of anisotropy provide a strong correlation (R2 ~ 76%) with K and a weaker correlation (R2 ~ 47%) with H. The results of this study can be exploited in computational mechanics frameworks for investigating the potential mechanical behavior of human vertebra and to develop strategies to treat or prevent pathological conditions such as osteoporosis, age‐related bone loss, and vertebral compression fractures. © 2020 The Authors. JBMR Plus published by Wiley Periodicals, Inc. on behalf of American Society for Bone and Mineral Research.
Opportunistic breast cancer screening for women aged 50 to 74, France, 2009 [Dépistage individuel du cancer du sein des femmes de 50 à 74 ans en France en 2009]

In 2004, France implemented a national mammographic breast cancer screening programme for women aged 50 to 74 years. Women can retain the option of having an opportunistic screening mammography under medical prescription, however data on opportunistic screening are lack- ing. By analysing the National Health Insurance scheme database (EGB) and a database including information on mammographies from radiolo- gists, the coverage of breast cancer could be estimated at 10% of the target population for opportunistic screening in 2009. The global rate of women's participation to breast cancer screening was 62% , there of 52% for organised screening. 7 to 8% of women had a mammography for the monitoring of a pathology or the location of a lesion. By age, the rate of screening (opportunistic and organised) increased markedly after 50 years due to the first women's invitation, then it remained stable and decreased after 70 years (50.7% in women aged 74). The existing databases have some limitations which affect the reliability of these estimates. To improve them, a specific codification of opportunist screening should be implemented in records of health care reimbursements. Furthermore all radiologists doing mammographies should report their activity in the Senolog database, and a quality control should be implemented.
High linearity and high power performance with barrier layer of sandwich structure and Al0.05GaN back barrier for X-band application

The high power and linearity performance of GaN-based HEMT for X-band application was achieved using the barrier layer of sandwich structure and Al0.05GaN back barrier. The AlGaN-sandwich-barrier can modulate polarization-graded field for more flat transconductance profile under the high drain bias. Only about 7.5% current collapse (CC) occurs for drain quiescent bias of 40 V. Due to the Al0.05GaN back barrier, the three-terminal off-state breakdown voltage (BVDS) of 260 V and a very small drain-induced barrier lowering (DIBL) of 2.7 mV V−1 is achieved. The AlGaN sandwich barrier combined with Al0.05GaN back barrier device exhibits a high current-gain cutoff frequency f T of 42 GHz@VDS = 10 V, and a high power-gain cutoff frequency f MAX of 130 GHz@VDS = 60 V. Load-pull measurement at 10 GHz revealed a saturated power density of 7.3 W mm−1 was achieved with an associated PAE of 29.2% and Gain of 10.6 dB. Two-tone measurement at 10 GHz showed an OIP3 of 38 dBm and a corresponding linearity figure-of-merit OIP3/PDC of 4.5 dB. These results demonstrate the great potential of AlGaN-sandwich -barrier/GaN/Al0.05GaN HEMTs as a very promising alternative to high power and high linearity X-band power amplifier.
Risk and Maintenance Factors for Eating Disorders: An Exploration of Multivariate Models on Clinical and Non-Clinical Populations

The recognition of factors involved in the development and maintenance of eating disorders (EDs) may support the choice of therapeutic strategies and improve the prevention/treatment of eating pathologies and their outcomes. Based on this consideration, the overall purpose of the chapter is to investigate how some psychological characteristics link to EDs. It is organized as follows. First, the epidemiological aspects, risk, and maintaining factors for ED are outlined. Next, we present the findings from our two studies. The purpose of the first study was to identify predictors associated with the severity of eating symptomatology. Then, the objec-tive of the second study was to provide an understanding of the relationship among perceived parental bonding, self-esteem, perfectionism, body shame, body mass index, and ED risk and mainly to test a predictive ED risk model in a non-clinical sample. In conclusion, the major findings and practical implications are discussed.
The Effect of Destination Image, Memorable Tourism Experience with Second Order Construct towards Revisit Intention: Study in Karimunjawa National Park

The tourism sector is one of the sectors that experienced significant development. Indonesia is one of the countries that are developing the tourism industry because of the economic needs. The main objective of this research is to prove the influence of destination image, memorable tourism experience that is measured using the second order method, toward revisit intention in Karimunjawa National Park. Method of collecting data is using a questionnaire. Respondent samples obtained were 145 respondents with purposive sampling technique. Data analysis is using PLS. This study shows that the image of a destination has a positive influence on revisit intention via the mediating effect of memorable tourism experiences.
Análise Comparativa Entre Modelos Dinâmicos Aplicados ao Rastreamento de Objetos Manobrantes

In object tracking problems, one of the concerns is the choice of the mathematical model that represents the tracking system, especially the object’s dynamics. In the literature, there are several dynamic models (cartesian and polar) that can be used to represent the object maneuvers. However, some of these dynamic models represent only two-dimensional movements. This paper has two main objectives: restructure some of the two-dimensional polar dynamic models found in the literature, in such a way to represent maneuvering objects trajectories in a three-dimensional space, and compare these restructured dynamic models with a threedimensional cartesian dynamic model from the literature. In order to verify if the restructured models are suitable, they will be implemented computationally in an extended Kalman filter. Mean squared errors based on estimations and code runtime will be used as performance criteria. For the trajectories measurements, it will be used simulated data from a trajectory generator software. Resumo: Em problemas de rastreamento de objetos, uma das preocupações é a escolha do modelo matemático que represente o sistema de rastreamento, especialmente a dinâmica do objeto. Na literatura, existem diversos modelos dinâmicos (cartesianos e polares) que podem ser utilizados para representar as manobras do objeto. Entretanto, uma parte destes modelos dinâmicos representa apenas movimentações bidimensionais. Este artigo tem dois objetivos principais: reestruturar alguns modelos dinâmicos polares bidimensionais encontrados na literatura, de maneira a fazer com que representem trajetórias de objetos manobrantes no espaço tridimensional, e comparar tais modelos dinâmicos reestruturados com um modelo dinâmico cartesiano tridimensional da literatura. Para verificar se tais modelos são adequados, estes serão implementados computacionalmente em um filtro de Kalman estendido. Erros quadráticos médios de estimativas e o tempo de execução do código serão utilizados como critérios de desempenho. Para as medidas das trajetórias serão utilizados dados simulados a partir de um software gerador de trajetórias.
The call of the squeak beetle: bioacoustics of Hygrobia hermanni (Fabricius, 1775) revisited (Coleoptera: Hygrobiidae)

Abstract Hygrobiidae, or squeak beetles, originated in the Triassic-Jurassic and exhibit a relictual distribution in the Palaearctic, Oriental and Australasian regions. Hygrobiids are well known for their sound-producing abilities, although studies of their bioacoustics remain limited. Here we describe sound producing organs and bioacoustics of the Palaearctic Hygrobia hermanni (Fabricius, 1775). Plectra and pars stridens were examined in both sexes, and sound characteristics analysed. Despite small differences between male and female last abdominal ventrites, plectra were identical. Pars stridens, however, differed subtly, tooth ridges being wider in females. Calls of both sexes were harmonic, with peak frequency at 6.1 kHz, and secondary peak at 10.9 kHz; males exhibiting longer inter-chirp intervals. Calls changed with time in the laboratory, this possibly condition-related effect being more apparent in males. The differences found between sexes suggest that sound production in squeak beetles may function in intraspecific communication, in addition to being an antipredator device.
Correlates of vaccine-induced protection: methods and implications

The document presents an overview of definitions and methods in the area of immune correlates of vaccine-induced protection. This subject has far-reaching implications for the evaluation of vaccine efficacy, for passive protection, e.g. maternal immunity and risk screening, e.g. tuberculin testing or rubella antibody testing of pregnant women, as well as for basic understanding of pathogenesis and immunity.
HIV INFECTION AND CARDIOVASCULAR RISK PROFILE IN A RURAL SOUTH AFRICAN POPULATION: THE NDLOVU COHORT STUDY

Background Life expectancy increased in HIV-infected populations due to antiretroviral treatment (ART). Whether HIV-infection and/or ART increase cardiovascular risk against a background of increasing prevalence of obesity, hypertension and diabetes in low- and middle-income countries is not yet clear. To answer this question in a rural South-African population, the Ndlovu Cohort Study was designed. We describe the baseline distribution of cardiovascular risk factors in relation to HIV and ART. Methods The Ndlovu Cohort Study is a prospective cohort study of 1000 HIV-positive and 1000 HIV-negative adults from the Moutse area, Limpopo, South Africa with an intended follow-up duration of ten years. Information is collected on demographics, anthropometrics, life-style, kidney and liver function, CRP, glucose and proteinuria. Carotid intima-media thickness (CIMT) and pulse wave velocity (PWV) measurements are used to assess subclinical atherosclerosis, respectively arterial stiffness. Cardiovascular risk factors were compared between HIV-negative and HIV – positive participants, whether or not on ART. Data were adjusted for gender and age. Results By December 2015, 1053 participants were included, 66% women; 345 (32.8%) women were HIV-positive of whom 235 (68.1%) received ART. HIV-infected participants were significantly older (40.0 versus 37.3 years), and mainly women (73%). HIV was associated with a lower body mass index, lower total – and LDL cholesterol and a lower prevalence of hypertension and diabetes. ART was associated with increased HDL and triglyceride levels. Current smoking did not differ between groups (23.6%), HIV and ART were associated with higher CRP values. Framingham risk scores (FRS) did not differ between HIV+/HIV- and/or ART use. Conclusions HIV infection is accompanied by a lower prevalence of cardiovascular risk factors, although the level of inflammation is increased. So far, we found no evidence that the 10-year cardiovascular disease risk according to FRS is influenced by HIV infection or HIV treatment.