Miracle-dz/UniFAR-FTUs huggingface dataset:
Amino acids in enteral formula based on local fermented food for children with protein energy malnutrition

Protein-energy malnutrition still becomes a problem in the world and Indonesia. The enteral formula is needed in the process of fulfilling overall nutrition in the form of a liquid diet in malnourished patients to digest and absorb nutrients without any difficulties. Amino acid lysine, methionine, cysteine, threonine, and tryptophan are often deficits in children's food; even, malnourished children (stunting, wasting, or protein-energy malnutrition) have decreased amino acids. Tempeh gembus, fermented local food, is used as the main ingredient for the enteral formula, and the hydrolysate process is carried out and made into flour, resulting in more amino acids due to the process of protein breakdown. The making of enteral formula from local food fermentation aims to enable the community to optimize local food into more nutritious food so that it can be produced at the household scale. Other supplementary ingredients are isolated soy protein, pumpkin flour, maltodextrin, sugar, and soybean oil. The enteral formula is isocaloric and isoprotein; it is divided into two with different compositions of the hydrolysate of Tempeh gembus flour. This study aims to determine the content of protein, amino acids, and limiting amino acids in the enteral formula. The amino acid analysis was performed using the HPLC method. Amino acid glutamate has the highest content in enteral formulas A and B (2,080 mg.100g-1and 1,950 mg.100g-1). The total amino acid content of enteral formula A is higher than that of enteral formula B with a difference of 210 mg.100g-1. Enteral formula A has a higher average amino acid content (1,400 mg.100g-1) than enteral formula B (1,378 mg.100g-1), and there is no significant difference (p = 0.812) between them. The enteral formula A has a higher amino acid content, but the highest protein content is in enteral formula B. The limiting amino acids in enteral formulas A and B are the methionine amino acids. Enteral formulas A and B can fulfill the needs of amino acids and be an alternative formula for Children with PEM.
Biosynthesis of Silver nanoparticles using Olive Wastewater

Biosynthesis of the metallic nanoparticle is gaining importance because it is a single-step process, nontoxic, environmentally acceptable, and easily scaled up. The present study investigated the biosynthesis of silver nanoparticles (AgNPs) via reacting olive wastewater filtrate (OWF) with silver nitrate, and the formation of AgNPs was confirmed by a color change of the reaction mixture and visible spectrophotometry. Additionally, the influence of pH, reaction time, AgNO3 concentration, temperature, and OWF volume on the proposed method was investigated. It was found that with increasing the mentioned parameters, the formation of the AgNPs was increased under the experimental conditions. The results showed that OWF represented a promising material for the biosynthesis of AgNPs.
FLIPPED CLASSROOM IS NOT FOR EVERY KIND OF STUDENT

Flipped classroom is a teaching strategy which has been greatly studied and utilized in various types and areas of teaching. Basically, it means that classes start being taught reverse to traditional classes. The teacher or instructor sends contents to students before lectures, adding the fact that students must study the subject matter before attending class. The advantages are clear: the time that each class takes with the teacher and classmates starts being used not to explain the subject, but for more complex questions which may be put only after clear knowledge of the subject. For this teaching strategy to work it is necessary that students do their homework, and that the teacher sends the correct and interesting study materials to students. In a phase of state of emergency-teaching or mixed teaching (presently and distance) caused by the COVID-19 global pandemic, flipped classroom started being much more used, namely in higher education and in areas such as IT. In this article we analyse 78 students of two IT courses, finding what type of students consulted the study materials sent by the teacher before lectures: we compare the characteristics of students, namely gender, age, course, attendance to classes (synchronous distance classes and laboratory classes at the university), as well as final classifications (divided into 4 levels and dropout). Thus, we will get to know for which type of students the effective use of the flipped classroom strategy may cause efficient learning and who are the students who will never do their previous homework. Keywords— Flipped classroom, COVID-19, e-learning, programming fundamentals.
Phytochemical and proximate composition of leaves of Anacardium occidental

Phytochemical analysis is an important step leading to the isolation and characterization of novel compounds with promising biological and pharmacological activities. The aim of this study was to investigate the phytochemical and proximate composition of leaves of Anacardium occidentale. Qualitative phytochemical screening and proximate analysis were performed on the plant leaves using standard procedures. The results revealed the presence of alkaloids, flavonoids, tannins, glycosides, saponins, and terpenoids. However, steroids were not detected. With the exception of glycosides, all the detected phytochemicals were more relatively abundant in air-dried sample than in sun-dried sample. Results of proximate analysis showed that the leaves of A. occidentale contained more Nitrogen-Free Substances (NFS) and low protein content. These results show that the leaves of Anacardium occidentale is a reservoir of important phytochemicals .
EDUCATIONAL ASPECTS OF ADULT PARTICIPATION IN PLAYFUL ACTIVITIES

Playfulness in adulthood has been shown to be un-researched scientific issue. We believe that it is because of earlier non-recognition of this issue as a special field of study, but also the existence of a popular belief that the playful activities are reserved only for children. Just because of the lack of initiative and coherent researches that take into account playful activities in adulthood and characteristic of playfulness as a personal trait this research can be considered as the first research of that kind in the Republic of Serbia. The aim of this research is to determine adult perceptions of their playfulness and dominant cognitive qualities of playfulness. Adult Playfulness Trait Scale was used (APTS, Shen, Chick & Zin, 2014) to explore adult playfulness and inherent cognitive characteristic of this personal trait. Research sample consists of 1234 adult individuals aged from 18 to above 60 years from a cities and villages of Serbian area. The results of this research show that respondents recognize and highly value all tree sub-dimensions of playfulness trait: fun-seeking motivation, uninhibitedness and spontaneity. An important finding of this research is one that indicates on the characteristics of fun-seeking motivation sub-dimension as dominant one.
Y-Family DNA Polymerases and Translesion Synthesis

Article: RT0472 DNA polymerases are specialized in the synthesis and repair of the genetic material. Y-family DNA polymerases lie at the heart of the mutagenesis process, a process commonly known as translesion synthesis. Y-family DNA polymerases have special characteristics of synthesizing the bases on damaged DNA. Translesion synthesis (TLS) is a process carried out by special polymerases for the prevention of cell death. This article mainly emphasizes the process carried out by DNA polymerases for prevention of cell death viz., TLS along with their necessities, and also for error-prone replication. Popular Art ic le Art ic le History Received in 6th January 2021 Received in revised form 9th January 2021 Accepted in final form 10th January 202
Nonlinear Chemical Dynamics and Synchronization

Nonlinear Chemical Dynamics and Synchronization A dissertation presented to the Faculty of the Graduate School of Arts and Sciences of Brandeis University, Waltham, Massachusetts by Ning Li Alan Turing’s work on morphogenesis, more than half a century ago, continues to motivate and inspire theoretical and experimental biologists even today. That said, there are very few experimental systems for which Turing’s theory is applicable. In this thesis we present an experimental reaction-diffusion system ideally suited for testing Turing’s ideas in synthetic “cells” consisting of microfluidically produced surfactant-stabilized emulsions in which droplets containing the Belousov-Zhabotinsky (BZ) oscillatory chemical reactants are dispersed in oil. The BZ reaction has become the prototype of nonlinear dynamics in chemistry and a preferred system for exploring the behavior of coupled nonlinear oscillators. Our system consists of a surfactant stabilized monodisperse emulsion of drops of aqueous BZ solution dispersed in a continuous phase of oil. In contrast to biology, here the chemistry is understood, rate constants are measured and interdrop coupling is purely diffusive. We explore a large set of parameters through control of rate constants, drop size, spacing, and spatial arrangement of the drops in lines and rings in one-dimension (1D) and hexagonal arrays in two-dimensions (2D). The Turing model is regarded as a metaphor for morphogenesis in biology but not for prediction. Here, we develop a quantitative and falsifiable reaction-diffusion model that we experimentally test with synthetic cells. We quantitatively establish the extent to which the Turing model in 1D describes both stationary pattern formation and temporal synchronization of chemical oscillators via reaction-diffusion and in 2D demonstrate that chemical morphogenesis drives physical differentiation in synthetic cells.
The Effect of PGPR Inoculation on the Growth of Wheat

Many agricultural soils of Iran have high pH, resulting in low availability of Fe and Zn. The potentials of nonsymbiotic plant growth-promoting rhizbacteria (PGPR) for stimulating plant growth have been extensively used during recent decades. This experiment was carried out in growth chamber to evaluate the effects of siderophoreproducing Pseudomonads on the growth as well as Fe and Zn uptake of wheat. A randomized complete block design experiments was conducted using with Alborz genotype (an efficient phytosiderophore-producing bread wheat) treated with either 7NSK2 strain as a siderophore positive (sid) or with MPFM1 mutant strain of the same isolate as a siderophore negative (sid) treatments with three replications. The potentials of these strains for auxin production and phosphate solubilizing activity were evaluated by standard methods. The results showed that inoculation with sid strain increased dry matter production in shoots as compared with the control (sterile condition) or with sid strain. Likewise, the concentration of chlorophyll a in leaves of sid and sid treatments were 1.27 and 0.41 g mg of fresh weight, respectively, and the concentration of chlorophyll b were measured to be 1.09 and 0.35 g mg of fresh weight, respectively, indicating significantly more chlorophyll formation due to inoculation with sid as compared with sid . The uptake of Fe by roots and its rate of translocation to the shoots were greater for the sid treated plants as compared with the sid treated ones, indicating that siderophores increased the rate of Fe uptake by wheat. The effect of microbial inoculation on shoot Zn was not significant, but increased the concentration of Zn on roots compared with control. The results suggested that the siderophores of Pseudomonads may involve on increasing bioavailability of iron.
High energy consumption and data traffic, critical production conditions and proprietary software

T he production and use of digital technologies and services is associated with environmentally and socially problematic developments. These are related both to the way Information and Communications Technology (ICT) devices are produced, used and disposed of, and to the design and use of software and the associated volume of data traffic. It is therefore essential that the material (energy and resources for the production, operation and disposal of hardware) and immaterial foundation of digitalisation (e. g., software, information, knowledge, etc.) are more closely integrated. Aspects such as modular product design, repairability, transparent supply chains and the use of public and free source codes and licences play a decisive role in making hardware and software sustainable. This article outlines the basic approaches that must be considered for a sustainable design of hardware and software and illustrates the political options.
Optimal Route for Tranexamic Acid in Diabetics and Obese Patients Undergoing Primary Total Knee Arthroplasty-a Data from Randomized Study

PURPOSE OF THE STUDY To determine the optimal strategy for tranexamic acid (TXA) administration in diabetic patients, smokers and obese patients (BMI > 30 kg/m2) undergoing primary total knee arthroplasty (TKA). MATERIAL AND METHODS The total of 400 consecutive patients indicated for primary TKA were randomised into 4 basic groups with different TXA administration regimens. Group 1 (IV1) had a single intravenous dose (15 mg TXA/kg) applied prior to skin incision. Group 2 (IV2) got two intravenous doses (15 mg TXA/kg): one prior to skin incision and one subsequently 6 hours after the first dose. Group 3 (TOP) had 2 g TXA in 50 ml of saline irrigated topically at the end of the surgery. Group 4 (COMB) combined IV1 and TOP regimens. We monitored the amount of total blood loss (TBL), haemoglobin drop, use of blood transfusions (BTs), and complications in each patient. Follow-up period was one year postoperatively. RESULTS In the group of diabetic patients (n = 87; 21.7%) the lowest TBL was observed in the order: IV1, IV2 > COMB > TOP. In the obese patients (BMI > 30 kg/m2; n = 242; 60.5%), TBL was significantly lower in the intravenous regimens (IV1: p = 0.002; IV2: p = 0.005, respectively) than in the TOP regimen. In the smoking patients (n = 30; 7.5%), TBLs were significantly lower in the order: IV1 > IV2 > COMB > TOP. DISCUSSION Individualised approach to prevention and therapy is a recent trend, also because comorbidities significantly affect the result of the intervention. In the case of diabetes, obesity and smoking, there is a proven link to early post-operative infections, mainly due to poorer innate immunity. It is conceivable, though, that the occurrence of infectious complications is also contributed to by larger hematomas or hemarthroses which are largely preventable. CONCLUSIONS In the diabetic and obese patients (BMI > 30 kg/m2), the combined topical/intravenous TXA application and two intravenous doses of TXA interventions were shown to be the most effective. However, no evidence of superiority of any of the TXA administration routes was obtained in the smokers. None of the TXA protocols was associated with a higher incidence of complications or early reoperation following TKA surgery.
User-centred design and evaluation of future flight deck technologies

This work presents an overview of the Human Factors methodologies, and applications thereof, that can be utilised across the design lifecycle of new technologies entering future commercial aircrafts. As advances are made to the architecture of commercial aircraft cockpits, it is vitally important that these new interfaces are safely incorporated and designed in a way that is usable to the pilot. Incorporation of Human Factors is essential to ensuring that engineering developments to avionic systems are integrated such that pilots can maintain safe interactions, while gaining information of value. Taking work from previous research studies, a case study example of technological advancements during its early conceptual stages is presented. This shows how different methods and processes can be applied and combined to ensure that the user is included within the design and evaluation of new flight deck technologies.
The Mediating Effect of Enterprise Resource Planning (ERP) Between Production Cost and Improving Performance of Yemen Pharmaceutical Companies

IJCRT2103066 www.ijcrt. org arch Thoughts (IJCRT) International Journal of Creative Rese 503  Abstract: this study aims to investigate the mediating effect of enterprise resource planning between production cost and improving performance of Yemen pharmaceutical companies as well as the impact of production cost on performance and ERP. The cross-sectional method is used by this study. For measuring the impact of ERP on improving the performance, structural questionnaire is used and distributed to 258 employees within the industry. The result shows a significant and positive mediating impact of ERP on production cost and improving the performance of the Yemen pharmaceutical companies. Also confirmed a significant impact of production costs that the variable cost, marginal cost, and total cost on the pharmaceutical companies' performance in Yemen as well as ERP.
Salvianolic acid B protects against acute and chronic liver injury by inhibiting Smad 2 C / L phosphorylation

Salvianolic acid B (Sal B) has strong antioxidant and anti-fibrosis effects, which are related to the transforming growth factor β/Smad signaling pathway. However, how Sal B affects this antioxidant pathway and the phosphorylation (p-) of Smad2 at both the COOH-terminal (pSmad2C) and linker region (pSmad2L) are unknown. The aims of the present study were to investigate the underlying mechanisms of Sal B on acute and chronic liver injury induced by CCl4 and H2O2, and its effects on p-Smad2C/L. In in vivo experiments, acute and chronic liver injury models were induced by CCl4, and the oxidative damage cell model was established in vitro with H2O2. Liver histopathology was assessed using hematoxylin and eosin and Van Gieson's staining. Moreover, serum biochemical indicators were analyzed using specific assay kits. Furthermore, the present study evaluated the oxidant/antioxidant status in acute and chronic liver injury models by oxidative stress parameters such as malondialdehyde, glutathione and superoxide dismutase. In addition, western blot analysis was performed to analyze the protein expression levels of pSmad2C, pSmad2L, nuclear factor erythroid-2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1). It was found that Sal B improved liver histology, decreased the levels of aminotransferase and attenuated oxidative stress in acute and chronic liver injury models. Additionally, the protein expression levels of pSmad2C and pSmad2L were decreased, but Nrf2 and HO-1 expression levels were increased both in vivo and in vitro. Collectively, the present results suggested that Sal B may protect against acute and chronic liver injury via inhibition of Smad2C/L phosphorylation, and the Nrf2/HO-1 signaling pathway may play an important role in this process.
Retoryka nowych mediów/nowych wyzwań Rhetoric of new media/new challenges

Taking a cognitive lexical semantics perspective, the article introduces the concept of conceptual silencing as a rhetorical tool. Understood as a process of conceptual dissolution of meaning to offer a more coarse-grained sense of an expression, conceptual silencing is demonstrated to have a potential rhetorical value in that it allows for more opaque reproduction of ideology. From a cognitive linguistic standpoint, the process of conceptual silencing hinges upon a polysemous nature of a lexical item and boils down to triggering a given sense of a given lexical item in a given context. To illustrate the workings of conceptual silencing, the article reports on a case study of the lexical item Europe in the Guardian press discourse. It is demonstrated that the ultimate effect of conceptual silencing is silencing the ‘European Union’ senses under the guise of the lexical item Europe. Artykuł wprowadza i omawia – z perspektywy kognitywnej semantyki leksykalnej – koncept pojęciowego wyciszania znaczenia jako narzędzia retorycznego. Pojęciowe wyciszanie znaczenia – rozumiane jako proces pojęciowego rozmywania znaczenia w celu uzyskania bardziej ogólnego sensu – ma potencjał retoryczny, ponieważ umożliwia upowszechnianie ideologii w mniej czytelny dla odbiorcy sposób. Z perspektywy językoznawstwa kognitywnego proces pojęciowego wyciszania znaczenia bazuje na polisemii jednostki leksykalnej i sprowadza się do aktywowania jej określonego sensu w danym kontekście. W celu zobrazowania niniejszego procesu przedstawione zostaje studium przypadku jednostki leksykalnej Europa w dyskursie prasowym dziennika „Guardian”, pokazujące, iż proces pojęciowego wyciszania znaczenia najwyraźniej przejawia się w wyciszaniu tych sensów jednostki leksykalnej Europa, które odnoszą się do Unii Europejskiej.
Concept Drift Detection Based on Pre-Clustering and Statistical Testing

Stream data processing has become an important issue in the last decade. Data streams are generated on the fly and possibly change their data distribution over time. Data stream processing requires some mechanisms or methods to adapt to the changes of data distribution, which is called the concept drift. Concept drift detection can be challenging due to the data labels are not known. In this paper, we propose a drift detection method based on the statistical test with clustering and feature extraction as preprocessing. The goal is to reduce the detection time with principal component analysis (PCA) for the feature extraction method. Experimental results on synthetic and real-world streaming data show that the clustering preprocessing improve the performance of the drift detection and feature extraction trade-off an insignificant performance of detection for speedup for the execution time.
The Impact of Military Strategic Thinking on Japanese International Economic Relations In the Post WW II Period

Japan's economy is invariably seen as a prime example of a capitalist system and an analysis of the elements on which the Japanese economy is founded seems to lead inexorably to the conclusion that Japan is an established member of the group of highly developed capitalist nations. Although the post-war economic crises have also affected the Japanese colossus, they have resisted due to the diversification of risks, the clients, the collaboration with multiple companies, the adaptation to new technologies, the innovation, the flexibility and above all, due to the formidable force of the Japanese people to overcome difficulties. Japan has a tradition of success, based on the military performance of the past. The orientation towards the performance of the Japanese companies, by the strategic character, can be correlated with the management of the military doctrine, both the classical and the modern one. The theme is anchored in reality because Japanese companies are a benchmark for emerging economies, as is the case in Romania.