Miracle-dz/UniFAR-FTUs huggingface dataset:
CRONOLOGIA DO DESENVOLVIMENTO EMBRIONÁRIO E FETAL DE RATOS CONFORME A DATAÇÃO DO INÍCIO DA PRENHEZ

Para a realizacao de estudos em teratologia e essencial o conhecimento da cronologia do desenvolvimento embrionario e fetal do animal usado na experimentacao. Neste trabalho, fez-se um levantamento bibliografico sobre as datas correspondentes aos principais eventos do desenvolvimento embrionario e fetal de ratos, o modelo experimental mais utilizado para tais estudos. Observou-se que ha grande variabilidade na datacao de um determinado evento embrionario/fetal, dependendo dos autores consultados, embora exista certa coerencia nas fases iniciais do desenvolvimento embrionario.
Test de spécifications de services de télécommunication

Ce travail aborde le probleme de la validation de specifications de services telephoniques et notamment la recherche d'interactions entre services. Une interaction correspond a la modification du comportement d'un ou plusieurs services, du fait de la coexistence des services. L'interaction est un obstacle majeur au developpement de l'offre de services de telecommunications. La validation de specifications requiert une modelisation des services et du reseau sous-jacent. Nous proposons une methode de specification formelle et de validation de services. Celle-ci est basee sur l'utilisation d'un formalisme synchrone pour la modelisation et la specification, et sur la mise en oeuvre de methodes de test pour la validation. Nous avons a cette fin propose une methode de test adaptee au probleme. Cette methode a ete integree a Lutess, un environnement de test fonctionnel de systemes reactifs synchrones, reposant sur un principe de generation de donnees dynamique et aleatoire. Elle est basee sur la notion de "guidage par schemas". Un schema represente une classe de comportements de l'environnement du systeme sous test, comportements que l'on souhaite tester principalement, soit parce qu'ils sont realistes, soit parce qu'ils conduisent a une situation estimee critique. Cette methode a ete formalisee, puis validee experimentalement dans plusieurs etudes de cas consequentes, en particulier lors du premier concours de detection d'interaction propose en marge de la conference "Feature Interaction Workshop", qui a consacre Lutess "Meilleur outil pour la detection d'interactions".
Improving IPv6 wireless ad hoc networks QoS via enhanced flow label with stability based Dynamic Source Routing scheme

This paper will present an enhanced Dynamic Source Routing (DSR) routing protocol where it utilizes the IPv6 Flow Label to provide Quality-of-Service (QoS) to the real time applications in IPv6 wireless ad hoc networks. Conventional DSR routing protocol is enhanced to induce better QoS in dynamic nature ad hoc networks. Internet Engineering Task Force (IETF) presented Flow Label with 20 bits in the IP packet header to provide special handlings to real time transmissions where they require high QoS services in the network. Multimedia applications required low delay, low packet drop and efficient delivery. Preliminary results of the proposed scheme will be discussed in this paper where the scheme utilized the Flow Label in IPv6 packet header to reserve the resources in order to provide a better performance in the dynamic nature ad hoc network.
Love Is in the Gaze

Reading other people’s eyes is a valuable skill during interpersonal interaction. Although a number of studies have investigated visual patterns in relation to the perceiver’s interest, intentions, and goals, little is known about eye gaze when it comes to differentiating intentions to love from intentions to lust (sexual desire). To address this question, we conducted two experiments: one testing whether the visual pattern related to the perception of love differs from that related to lust and one testing whether the visual pattern related to the expression of love differs from that related to lust. Our results show that a person’s eye gaze shifts as a function of his or her goal (love vs. lust) when looking at a visual stimulus. Such identification of distinct visual patterns for love and lust could have theoretical and clinical importance in couples therapy when these two phenomena are difficult to disentangle from one another on the basis of patients’ self-reports.
Genotypes of human polyomaviruses in urine samples of pregnant women in Taiwan

The viral DNA of human polyomaviruses JC virus (JCV) and BK virus (BKV) was detected by the polymerase chain reaction (PCR) in urine samples from 31 pregnant women in Taiwan. A pair of appropriate primers amplified both JCV and BKV DNA of the regulatory region simultaneously in PCR. An oligonucleotide probe homologous to both JCV and BKV regulatory region was used subsequently to detect the viral DNA by Southern blotting after PCR amplification. Approximately 36% of the examined urine samples were human polyomavirus positive. The genotypes of JCV and BKV were determined by DNA sequencing of their regulatory regions. Besides CY archetype, a new strain (Taiwan‐1) of JCV with a pentanucleotide (GGGAA) deletion and a new strain (Taichung‐1) of BKV with two nucleotide alterations within the regulatory region were found in the urine samples. Eight of the examined samples were JCV infected, one was BKV infected, and two were JCV and BKV mix‐infected. The JCV positive individuals were infected by CY archetype and Taiwan‐1 strain equally. However, Taichung‐1 strain was the only BKV strain found in the BKV positive individuals. © 1996 Wiley‐Liss, Inc.
Optimal siting of hydrological monitoring stations with respect to remote sensing-based geo-environmental patterns

The management of sustainable and dependable water resources in a semi-arid coastal watershed in South Texas, such as the Choke Canyon Reservoir Watershed (CCRW), is deemed critical because of complex relationships among ecosystems, social development, human health, and economic progress. To retrieve key hydrological information constrained by a limited budget, a set of hydrological monitoring stations in support of investigation of drought and flood impacts in the CCRW were identified by a grey integer programming (GIP) approach under uncertainty. The area of interest is divided into eight hundred cells in GIS for the 15,000-square-kilometer watershed area. Each cell size is 4-by-4 kilometer. The cells are assigned weights that could quantify monitoring values in terms of soil permeability, precipitation rate, evaporation rate, predicted soil moisture, evapotranspiration rate, and the normalized difference vegetation index (NDVI). RADARSAT and LANDSAT satellite images are acquired in support of determination for part of the weighted values, such as soil moisture and vegetation index, in the hydrological cycle. The weights are aggregated as coefficient matrices in a GIP model that help identify the most suitable locations. Fifteen cells are chosen out of eight hundred candidates and are ranked consecutively. Eventually, only five sites were selected after a site investigation based on site accessibility and practical uses of the selected sites. It may help collect a vital database at strategic locations, including wind speed, wind direction, soil moisture, ambient temperature, soil temperature, and relative humidity periodically for drought and flood management in the future
The First Year of Bereavement †.

Follow up what we will offer in this article about first year of bereavement. You know really that this book is coming as the best seller book today. So, when you are really a good reader or you're fans of the author, it does will be funny if you don't have this book. It means that you have to get this book. For you who are starting to learn about something new and feel curious about this book, it's easy then. Just get this book and feel how this book will give you more exciting lessons.
ABILIFY®, aripiprazole : premier agoniste partiel dans le traitement de la schizophrénie

Dans un premier temps, nous nous interesserons a la schizophrenie : cette maladie touche un nombre important de personnes dans le monde avec des consequences socio-economiques et de mortalite desastreuses. L’etude de sa physiopathologie, encore mal connue, ouvre la voie de strategies therapeutiques nouvelles. Par la suite, nous analyserons l’arsenal therapeutique classique disponible en France. Enfin, nous nous pencherons sur une nouvelle classe de medicament antipsychotique : les agonistes partiels du systeme dopamine-serotonine dont l’efficacite et surtout la tolerance procurent une avancee interessante dans la prise en charge therapeutique des patients schizophrenes, et ceci au travers de la seule molecule mise sur le marche actuellement : ABILIFY ®, aripiprazole.
Superficial cervical plexus block for vocal cord surgery in an awake pediatric patient.

UNLABELLED Medialization thyroplasty is a surgical procedure that decreases the incidence of dysphonia and dysphagia in patients who have vocal cord paralysis. We report a case of a pediatric patient who underwent this procedure with minimal sedation and bilateral superficial cervical plexus blockade. The use of a regional technique provided analgesia while allowing the patient to phonate at the request of the surgeon. IMPLICATIONS Medialization thyroplasty is a surgical procedure that decreases the incidence of dysphagia and dysphonia in patients with vocal cord paralysis. This procedure is best performed in a patient who maintains the ability to phonate. We report a case of medialization thyroplasty in a pediatric patient after bilateral superficial cervical plexus blocks with minimal sedation.
Is there a role for EU Integrated Product Policy (IPP) in solving global environmental problems? Investigating IPP's capacity for correction at source in a global context

In its ‘Strategy for Sustainable Development’, the European Commission (EC) refers to the fact that economic activities within the EU borders increase the pressure on the environment in other parts of the world, particularly in so-called developing countries, through imports of natural resources and exports of waste (European Commission 2001). In its statement, the EC points to another dimension of global environmental problems that have been typically associated with diffuse emissions into air and water. Now, environmental problems formerly labelled ‘regional’ are conceived to be globally related as well.
The relationship between space-vector modulation and regular-sampled PWM

The relationship between regular-sampled pulse-width modulation (PWM) and space-vector modulation for inverter drives is defined, and it is shown that, under certain circumstances, the two approaches are equivalent. The various possibilities of adding a zero-sequence component to the regular-sampled sinusoidal modulating wave are explored, and these effects are quantified. It is shown that this leads to "equal-null" pulse times, which extend the linear modulation range and simplify the microprocessor implementation.
Silencing of choline acetyltransferase expression by lentivirus‐mediated RNA interference in cultured cells and in the adult rodent brain

RNA interference (RNAi) is a potent mechanism for local silencing of gene expression and can be used to study loss‐of‐function phenotypes in mammalian cells. We used RNAi to knockdown specifically the expression of choline acetyltransferase (ChAT), the enzyme of acetylcholine biosynthesis, both in cultured cells and in the adult brain. We first identified a 19‐nucleotide sequence in the coding region of rat and mouse ChAT transcripts that constitutes a target for potent silencing of ChAT expression by RNAi. We generated a lentiviral vector that produces both a small hairpin RNA (shRNA) targeting ChAT mRNAs and the enhanced green fluorescent protein (EGFP) reporter protein to facilitate identification of transduced cells. In the cholinergic cell line NG108‐15, there was at least 90% less of the ChAT protein, as measured by assaying its enzymatic activity, 3 days postinfection with this vector than in cells infected with a control vector. The vector was used to transduce cholinergic neurons in vivo and reduced ChAT expression strongly and specifically in the cholinergic neurons of the medial septum in adult rats, without affecting the expression of the vesicular acetylcholine transporter. This lentiviral vector is thus a powerful tool for specific inactivation of cholinergic neurotransmission and can therefore be used to study the role of cholinergic nuclei in the brain. This lentiviral‐mediated RNAi approach will also allow the development of new animal models of diseases in which cholinergic neurotransmission is specifically altered. © 2008 Wiley‐Liss, Inc.
Uma contribuição para a minimização do número de stubs no teste de integração de programas orientados a aspectos

xv 1 Introducao 1 1.1 Teste de programas orientados a aspectos . 1 1.2 Motivacoes . 3 1.3 Objetivos . 4 1.4 Organizacao do trabalho . 5 2 Introducao ao teste de software com enfase para o teste de integracao 7 2.1 Consideracoes iniciais . 7 2.2 Conceitos basicos de teste de software . 8 2.3 Tecnicas e criterios de teste . 11 2.3. 1 Teste funcional . 11 2.3. 2 Teste estrutural . 12 2.3. 3 Teste baseado em erros . 13 2.3. 4 Teste baseado em modelos . 14 2.4 Fases de teste . 14 2.4. 1 Teste de unidade . 16 2.4. 2 Teste de integracao . 16 2.4. 3 Teste de sistema . 17 2.5 Estrategias de ordenacao de classes no teste de integracao OO . 18
Traumatic intracerebellar haematoma: To operate or not to operate?

Abstract Background. Pure cerebellar haematoma of traumatic etiology, without associated posterior fossa sub- or epi-dural haematomas is a rare entity and has been reported to have a poor outcome. We report 23 patients with traumatic intracerebellar haematoma. We sought to study the pattern of such presentations and assess the factors which could be associated with their outcome. Methods. A retrospective review of prospectively collected data for all patients who were admitted for the management of traumatic intracerebellar haematoma at Rajendra Institute of Medical Sciences, Ranchi, India provided data for the 23 consecutive patients admitted for aforesaid over a seven-year study period. Medical records, diagnostic imaging and operative notes were reviewed for all patients. We divided the patient pool in to two groups based on their GCS score at the time of presentation – Group A (GCS > 7) and Group B (GCS ≤ 7). The association of different allied factors was studied and statistically analyzed. The relevant medical literature was also reviewed. Results. Most Group B patients were found to be associated with poor outcome at hospital discharge. The overall incidence of poor outcome in our study was 69.56%. GCS score at time of admission, allied supratentorial lesions, advanced age, condition of fourth ventricle and chest infection were found to be important factors which could be associated with poor outcome. Conclusion. Surgery in patients with the mentioned risk factors remains debatable and should be approached cautiously. Larger multi-institutional and meta-analytic studies are required to study and statistically establish the factors which might be associated with poor outcome in these patients. An algorithm which may be used in the management of traumatic intracerebellar haematoma patients is proposed.
Demystifying Preventive Equipment in the Competitive Athlete

Sports-related injuries are rising as the interest and participation in sports rise. Recent epidemiologic study suggested that one in five injuries in individuals 18 years or younger reporting to the emergency department were found to be sports related. These injuries also were found to account for up to 19% of primary care injury-related visits. In this article, we will be reviewing the use of five different types of sports protective equipment (ankle support, knee support, mouthguards, eyeguards, and helmets) and the protection provided by each with level of current evidence. We found that the literature supports the use of ankle braces and mouthguards in athletes. The use of knee braces and eye protection in some athletes is indicated. Helmets to prevent head injuries are supported, but it is uncertain if that extends to concussion prevention. Soccer headgear is not supported and needs randomized control studies to show benefit.
High-density nano-pillar SiOx-based resistive switching memory using nano-sphere lithography to fabricate a one diode - one resistor (1D-1R) architecture

A highly compact, one diode - one resistor (1D-1R) nano-pillar device architecture has been demonstrated using nano-sphere lithography (NSL) to fabricate SiOx-based resistive switching (RS) memory. The intrinsic SiOx-based resistive switching element and Si-based PN diode are self-aligned on the epitaxial silicon wafer using NSL and a deep-Si-etch process without using conventional photolithography. The DC electrical performance, an AC pulse response in the 50 ns regime, capability for multi-bit operation, and high readout margin immunity for sneak path issue demonstrate good potential for high-speed nonvolatile memory (NVM). The NSL fabrication process is an efficient, economical approach to enable large-scale patterning of 1D-1R architectures while providing excellent NVM performance for future applications.
Effect of Low-Dose Irradiation on Proliferation Dynamics in the Rostral Migratory Stream of Adult Rats ( ionizing radiation / rat brain / rostral migratory stream / cell proliferation )

The subventricular zone (SVZ) is the largest germinal zone of the mammalian brain, which persists until adulthood and retains the capacity to give rise to both neuronal and glial cells. In adult brain, the fate of progenitors of neurons and glia cells depends on their location. Progenitor cells of the hippocampal subgranular zone (SGZ) migrate into the granular cell layer of the dentate gyrus, progenitor cells of the SVZ migrate along the restricted pathway called the rostral migratory stream (RMS) to the olfactory bulb (OB). In the OB they migrate radially and those that survive differentiate into granular and periglomerular interneurons (AlvarezBuylla et al., 2002; Doetsch, 2003; Suzuki and Goldman, 2003), which can establish some functional connections (Zigova and Sanberg, 1999; Carleton et al., 2003). The SVZ of adult mammalian brain therefore serves as an important source of progenitors that could be used for neuroregenerative therapy. Thus, the SVZRMS-OB system represents an interesting experimental model for the study of the origin, migration and integration of new neurons into functional brain circuits. The SVZ progenitors are vulnerable to damage, whereas the neural stem cells are resilient and after moderate injury (but not after more severe injury) the SVZ can recover (Tada et al., 1999; Romanko et al., 2004). Therefore, after transient decrease, brain lesions generally induce an increase in SVZ neurogenesis or gliogenesis and cause cell emigration to ectopic location (Sundholm-Peters et al., 2005). Perinatal as well as adult SVZ not only have the capacity to replenish their own numbers, but also the ability to replace neurons and glia after different models of brain injuries (Kirschenbaum et al., 1999; Romanko et al., 2004; Ramaswamy et al., 2005). Ionizing radiation, currently used in the radiotherapy, can cause significant damage to normal mammalian brain especially in prenatal age. Local irradiation of the juvenile rat brain with the doses of 1–3 Gy caused expressive reduction in the number of neural stem and progenitor cells in the SVZ and increased apoptosis, but these changes were reversible (Amano et al., 2002). Whole-brain irradiation with large-scale doses (2–10 Gy) also caused a decrease in the number of SGZ cells and their progeny in the hippocampus of young mice in a dose-dependent fashion (Rola et al., 2004). To deter-
Future Aspects of Liver Biopsy: From Reality to Mathematical Basis of Virtual Microscopy

Tissue investigation remains one of the most reliable diagnostic ways in both general medical practice and liver pathology. At present, the routine liver biopsy investigation should include obtaining a representative tissue sample, adequate technological processing and application of histochemical stain panel [1-5]. The evaluation must be done in accordance with up-to-date disease classifications and validated diagnostic criteria [6]. Protocol approach is recommend‐ ed in order to decrease the variability in description. In case of chronic inflammatory liver dis‐ ease, semiquantitative evaluation of inflammatory activity by Knodell, Ishak, METAVIR or Scheuer score, or analogous system [7-11] must be applied. Additional methods as immuno‐ histochemistry or polymerase chain reaction are applied by necessity. The morphological evaluation of biopsy is a part of medical teamwork. It should be preceded by clinical and lab‐ oratory investigations and biopsy findings must be incorporated in the general patient’s in‐ formation. Many of these principles will remain in use in the nearest future. However, both clinical diagnostics and medical research undergo almost unlimited progress. The upcoming innovations in liver biopsy analysis include incorporation of digital image analysis, genetic investigations and immunohistochemistry for functionally important molecules as cytokines, cell cycle markers and viral life cycle markers into everyday practice.
A Protestant Legacy. Attitudes to Death and Illness among Older Aberdonians . By Rory Williams. Oxford, Clarendon Press, 1990. Pp. xiii + 371. No price.

Westcott and Hort, it is very necessary that the work be done again. A particular service done by Kilpatrick therefore, regardless of whether or not one accepts his method, is that he has insisted on the priority of thought and attention to the character of the variants. This volume will repay careful study, not only by text critics, but by anyone interested in the character of the New Testament documents.
Impact of random pointing and tracking errors on the design of coherent and incoherent optical intersatellite communication links

Given the RMS transmitter pointing error and the desired probability of bit error (PBE), it can be shown that an optimal transmitter antenna gain exists which minimizes the required transmitter power. Given the RMS local oscillator tracking error, an optimum receiver antenna gain can be found which optimizes the receiver performance. The impact of pointing and tracking errors on the design of direct-detection pulse-position modulation (PPM) and heterodyne noncoherent frequency-shift keying (NCFSK) systems is then analyzed in terms of constraints on the antenna size and the power penalty incurred. It is shown that in the limit of large spatial tracking errors, the advantage in receiver sensitivity for the heterodyne system is quickly offset by the smaller antenna gain and the higher power penalty due to tracking errors. In contrast, for systems with small spatial tracking errors, the heterodyne system is superior because of the higher receiver sensitivity. >
Pulmonary embolism.

BACKGROUND Pulmonary embolism remains a common and potentially preventable cause of death. OBJECTIVE This article reviews the epidemiology, clinical features, diagnostic process, and treatment of pulmonary embolism. DISCUSSION Well recognised risk factors include recent hospitalisation, other causes of immobilisation, cancer, and oestrogen exposure. Diagnostic algorithms for pulmonary embolism that incorporate assessment of pretest probability and D-dimer testing have been developed to limit the need for diagnostic imaging. Anticoagulation should be administered promptly to all patients with pulmonary embolism with low molecular weight heparin being the initial anticoagulant of choice, although thrombolysis is indicated for patients presenting with haemodynamic compromise. Following initial anticoagulation warfarin therapy should be continued for a minimum of 3 months. Long term anticoagulation with warfarin should be considered in patients with unprovoked pulmonary embolism, due to an increased risk of recurrence after ceasing anticoagulation. The availability of new anticoagulants is likely to significantly impact on the treatment of patients with pulmonary embolism, although the exact role of these drugs is still to be defined.