Miracle-dz/UniFAR-FTUs huggingface dataset:
The Assessment of Sexual Functions in Women with Male Partners Complaining of Erectile Dysfunction: Does Treatment of Male Sexual Dysfunction Improve Female Partner's Sexual Functions?

The aims of this prospective study were to compare sexual functioning between women with male partners who have erectile dysfunction (ED) and women without partners with ED and also to investigate the effect of the treatment of male ED on female partner's sexual function. The study included 87 women and their male partners. We divided the women into two groups: 38 women with male partners complaining of ED (ED group) and 49 women with male partners who have no ED (control group). Of the men with ED, 30 were treated with penile prosthesis implantation (n = 17) or oral sildenafil citrate (n = 13). We evaluated all the men with the International Index of Erectile Function (IIEF; Rosen, Cappelleri, Smith, Lipsky, & Pena, 1999), physical examination, and color penile Doppler ultrasound. We evaluated female sexual function with the Female Sexual Function Index (FSFI; Rosen et al., 2000) to assess sexual desire, arousal, lubrication, orgasm, satisfaction, and pain. We compared female sexual function scores between the women of the male partners with and without ED and also compared before both groups and after the treatment of male partners in the ED group. Additionally, we compare the scores according to the type of treatment given to the male partners. Sexual arousal (p = 0.009), lubrication (p = 0.001), orgasm (p = 0.006), satisfaction (p = 0.000), pain (p = 0.039), and total score (p = 0.003) were highly significantly lower in the ED group than in the control group, although sexual desire did not differ between the two groups (p = 0.515). We investigated the effect of male ED on female sexual functions and found no statistically significant differences in the presence of organic type impotence, older age, and lower erection scores on the IIEF (p = 0.53, p = 0.15, and p = 0.1, respectively). After the treatment of male ED, we observed significant improvement in sexual arousal (p = 0.001), lubrication (p = 0.002), orgasm (p = 0.000), satisfaction (p = 0.000), and pain (p = 0.002) in the women. These findings suggest that female sexual function is affected by male erection status and may improve after the treatment of male sexual dysfunction.
Mortality in South Africa: Socio-economic profile and association with self-reported health

This paper exploits the first two waves of the National Income Dynamics Study (NIDS) to describe the socio-economic profile of mortality and to assess whether self-rated health status is predictive of mortality between waves. Mortality rates in NIDS are in line with estimates from official death notification data and display the expected hump of excess mortality in early and middle adulthood due to AIDS, with the excess peaking earlier for women than for men. We find evidence of a socio-economic gradient in mortality, with higher rates of mortality for individuals from asset-poor households and with lower levels of education. Consistent with evidence from many industrialised countries and a few developing countries, we find self-rated health to be a significant predictor of two-year mortality, an association that remains after controlling for socio-economic status and several other subjective and objective measures of health.
Expression and characterization of an α-glucosidase from Thermoanaerobacter ethanolicus JW200 with potential for industrial application

In this study, a new α-glucosidase gene from Thermoanaerobacter ethanolicus JW200 was cloned and expressed in Escherichia coli by a novel heat-shock vector pHsh. The recombinant α-glucosidase exhibited its maximum hydrolytic activity at 70°C and pH 5.0∼5.5. With p-nitrophenyl-α-D-glucoside as a substrate and under the optimal condition (70°C, pH 5.5), Km and Vmax of the enzyme was 1.72 mM and 39 U/mg, respectively. The purified α-glucosidase could hydrolyze oligosaccharides with both α-1,4 and α-1,6 linkages. The enzyme also had strong transglycosylation activity when maltose was used as sugar donor. The transglucosylation products towards maltose are isomaltose, maltotriose, panose, isomaltotriose and tetrasaccharides. The enzyme could convert 400 g/L maltose to oligosaccharides with a conversion rate of 52%, and 83% of the oligosaccharides formed were prebiotic isomaltooligosaccharides (containing isomaltose, panose and isomaltotriose).
SMARTKITCHEN Media Enhanced Cooking Environment

This work-in-progress paper describes our project SMARTKITCHEN, an interdisciplinary research project focusing on interactive display deployment in the kitchen - in particular around the cooking area. By applying a user-centered design approach the project aims to examine how screen-based interactive digital media can be accessed naturally in a constrained environment during the cooking process using multimodal interaction. Our main focus is on exploring new directions of supporting social and emotional aspects of the cooking experience. In this work-in-progress paper, we provide an overview on research directions, envisioned use-cases, and used technologies.
Timing of rapid diversification and convergent origins of active pollination within Agavoideae (Asparagaceae).

PREMISE OF THE STUDY Yucca species are ideal candidates for the study of coevolution due to the obligate mutualism they form with yucca moth pollinators (genera Tegeticula and Parategeticula). Yuccas are not the only species to exhibit a mutualism with yucca moths; the genus Hesperoyucca is pollinated by the California yucca moth (Tegeticula maculata). Relationships among yuccas, Hesperoyucca, and other members of subfamily Agavoideae are necessary to understand the evolution of this unique pollination syndrome. Here, we investigate evolutionary relationships of yuccas and closely related genera looking at the timing and origin of yucca moth pollination. METHODS In this study, we sequenced the chloroplast genomes of 20 species in the subfamily Agavoideae (Asparagaceae) and three confamilial outgroup taxa to resolve intergeneric phylogenetic relationships of Agavoideae. We estimated divergence times using protein-coding genes from 67 chloroplast genomes sampled across monocots to determine the timing of the yucca moth pollination origin. KEY RESULTS We confidently resolved intergeneric relationships in Agavoideae, demonstrating the origin of the yucca-yucca moth mutualism on two distinct lineages that diverged 27 million years ago. Comparisons of Yucca and Hesperoyucca divergence time to those of yucca moths (Tegeticula and Parategeticula, Prodoxidae) indicate overlapping ages for the origin of pollinating behavior in the moths and pollination by yucca moths in the two plant lineages. CONCLUSION Whereas pollinating yucca moths have been shown to have a single origin within the Prodoxidae, there were independent acquisitions of active pollination on lineages leading to Yucca and Hesperoyucca within the Agavoideae.
The pulmonary clock.

s are invited in this area. They should not exceed 250 words in length and should be typed double spaced, including title, first and last names of all authors, and the institution where the work was performed. Please designate the address for correspondence and identify who will present the paper. Abstracts should be submitted to the Scientific Program Chairman, Third World Congress for Bronchology, American College of Chest Physicians, 911 Busse Highway, Park Ridge, Illinois 60068 USA. The deadline for abstracts is 1 September 1981. Further information about the meeting can be obtained from the same address.
Émission X induite par particules chargées (PIXE) : applications

Cet article a pour but de fournir les informations pratiques et necessaires a la mise en oeuvre de la technique d'analyse PIXE dont les bases theoriques ont ete exposees precedemment (article [P 2 557]). En principe, elle est simple a mettre en oeuvre, puisqu'il suffit de placer un echantillon dans le faisceau, sans preparation particuliere en dehors de sa mise sous vide, pour obtenir en quelques minutes une composition qualitative. En realite, pour obtenir des resultats quantitatifs precis et optimiser la sensibilite, un certain nombre de precautions experimentales doivent etre prises quant a la forme de l'echantillon (solide, poudre deposee en couche mince ou frittee, liquide deshydrate ou preconcentre), a ses caracteristiques physiques (conductivite, etat de surface.) et, enfin, au type de faisceau utilise (ion, energie, flux) ainsi qu'a la geometrie d'analyse. Depuis quelques annees, la contrainte de la mise sous vide a meme pu etre levee puisque des faisceaux extraits a l'air sont maintenant disponibles, ce qui permet, entre autres, d'analyser des objets tres encombrants a pression atmospherique, notamment dans le domaine de l'art. Tous ces aspects seront developpes dans le paragraphe « Instrumentation ». Le chapitre suivant sera consacre aux traitements necessaires a l'expression des concentrations a partir des resultats experimentaux. Les codes actuels de deconvolution des spectres de fluorescence X permettent de resoudre la plupart des situations en cible mince et d'obtenir des resultats quantitatifs absolus sans faire appel a des echantillons standards. Les rendements d'emission X sont, en effet, bien connus ainsi que la reponse des detecteurs a semi-conducteur. Ces codes permettent egalement de travailler en cible epaisse, situation ou interviennent des effets de matrice sous forme de ralentissement des projectiles et d'attenuation du rayonnement X emis. Ces phenomenes peuvent etre modelises de maniere assez simple et l'analyse en cible epaisse est de plus en plus utilisee dans des cas ou aucune alternative n'est possible. Grâce a sa nature multielementaire, la methode mettant en oeuvre des micro-faisceaux permet de cartographier plus d'une dizaine d'elements au cours de la meme analyse avec des dimensions de balayage variant de 20 μm a 2 mm et une resolution spatiale optimale de l'ordre de quelques centaines de nanometres. L'utilisation de telles lignes de faisceaux est decrite dans ce traite (article [P 2 563]). Quelques exemples d'application pris dans des disciplines aussi diverses que les sciences de la vie et l'environnement, les sciences de la Terre, les sciences des materiaux, l'archeometrie. sont presentes dans la derniere partie de l'article. Les bases theoriques de la methode ont ete presentees dans l'article [P 2 557].
Langage élaboré et gliomes infiltrants : étude de sensibilité d’une batterie d’évaluation

Des plaintes langagieres sont souvent evoquees par les patients porteurs d’un gliome infiltrant. Ces troubles, souvent fins, peuvent passer inapercus lors de l’evaluation cognitive. Les batteries actuelles n’etant pas assez sensibles, elles ne permettent pas toujours d’objectiver ces difficultes. Il existe actuellement peu de tests evaluant les composantes langagieres de facon exhaustive. Ainsi, notre etude consiste a mettre en evidence la sensibilite de la batterie ELEA (Evaluation du Langage Elabore chez l’Adulte). Notre population se compose de 14 patients, porteurs d’un gliome et operes en condition eveillee. Le protocole propose comporte des epreuves executives et attentionnelles, une evaluation du retentissement de l’aphasie sur la vie quotidienne (score AHS et echelle de gravite du BDAE) ainsi que les 16 epreuves de l’ELEA. Les resultats a l’ELEA mettent en evidence la presence de troubles du langage elabore en pre- et post-operatoire. Nous observons des correlations entre les troubles du langage elabore et le grade tumoral, l’hemisphere atteint et le score AHS. En revanche, nous ne retrouvons pas d’influence significative du sexe, de l’âge et du niveau socioprofessionnel. L’evaluation approfondie du langage et la prise en charge orthophonique specifique des patients porteurs d’un gliome se revelent donc necessaires.
Heterogeneous Demographic and Cultural Profiles of Chinese American Patients Nonadherent to Colorectal Cancer Screening: A Latent Class Analysis

Background: Colorectal cancer (CRC) is one of the leading causes of cancer death in Chinese Americans, but their CRC screening rates remain low. Objective: We examined subgroups of Chinese American patients nonadherent to CRC screening guidelines to better inform clinical practices to effectively promote screening. Methods: Using latent class analysis of data from 327 participants recruited from 18 primary care clinics, we classified nonadherent patients based on sociodemographics, screening barriers, and attitudinal and clinical factors for CRC screening. Results: The best-fitting latent class analysis model described 3 distinctive classes: Western healthcare class (36%), Eastern healthcare class (18%), and mixed healthcare class (46%). Western healthcare class patients were highly educated, with average US residency of 20 years, a high level of English proficiency, the least Eastern cultural views of care, and the greatest exposure to physician recommendations, but reported having no time for screenings. Eastern healthcare class patients were highly educated seniors and recent immigrants with the least CRC knowledge and the most Eastern cultural views. Mixed healthcare class patients had low level of education, resided in the United States for 20 years, and half had sought services of their physicians for at least 3 years, but their knowledge and cultural views were similar to those of Eastern healthcare class patients. Conclusions: Nonadherent Chinese American patients are heterogeneous. It is essential to have future intervention programs tailored to address specific screening beliefs and barriers for subtypes of nonadherent patients. Implications for Practice: Training primary care physicians to recognize patients’ different demographic characteristics and healthcare beliefs may facilitate physicians’ communication with patients to overcome their barriers and improve screening behaviors.
A methodology for MOS transistor mismatch parameter extraction and mismatch simulation

This paper presents a methodology for mismatch parameter extraction and mismatch simulation using conventional electrical simulators, like HSpice. A measurement and extraction procedure has been carefully designed to be able to obtain reliable measurements of the mismatch parameters of a given technology. The correctness of this extraction procedure method has been checked through three different validation methods. We also present two methods for performing mismatch simulation with conventional circuit simulators (like HSpice) using the extracted parameters.
Mechanisms for the cardiovascular effects of glucagon‐like peptide‐1

Over the past three decades, at least 10 hormones secreted by the enteroendocrine cells have been discovered, which directly affect the cardiovascular system through their innate receptors expressed in the heart and blood vessels or through a neural mechanism. Glucagon‐like peptide‐1 (GLP‐1), an important incretin, is perhaps best studied of these gut‐derived hormones with important cardiovascular effects. In this review, I have discussed the mechanism of GLP‐1 release from the enteroendocrine L‐cells and its physiological effects on the cardiovascular system. Current evidence suggests that GLP‐1 has positive inotropic and chronotropic effects on the heart and may be important in preserving left ventricular structure and function by direct and indirect mechanisms. The direct effects of GLP‐1 in the heart may be mediated through GLP‐1R expressed in atria as well as arteries and arterioles in the left ventricle and mainly involve in the activation of multiple pro‐survival kinases and enhanced energy utilization. There is also good evidence to support the involvement of a second, yet to be identified, GLP‐1 receptor. Further, GLP‐1(9‐36)amide, which was previously thought to be the inactive metabolite of the active GLP‐1(7‐36)amide, may also have direct cardioprotective effects. GLP‐1's action on GLP‐1R expressed in the central nervous system, kidney, vasculature and the pancreas may indirectly contribute to its cardioprotective effects.
APLICAÇÃO DE CONTROLADORES FUZZY E PROPORCIONAL PARA UM ROBÔ SEGUIDOR DE PAREDE AUTÔNOMO EM AMBIENTE ESTÁTICO

A navegacao de robos moveis apresenta uma vari- edade de problemas, como a presenca de ruidos e disturbios, necessidade de fusao sensorial e a dificuldade na obtencao do modelo matematico que representa as interacoes fisicas do ambiente. Cabe ao sistema de controle prover comandos para a correta execucao dos movimentos do robo, de forma a alcancar algum objetivo proposto mesmo diante das adversidades do ambiente. Este artigo apresenta a aplicacao de diferentes tipos de sistemas de controle, como controladores fuzzy convencional, fuzzy hierarquico e proporcional, para a navegacao de um robo seguidor de parede em ambiente estatico, cujo objetivo e evitar colisoes e manter o robo a uma distância segura da parede. Foram feitas simulacoes em dois ambientes 3D e um experimento real para validacao da abordagem proposta. As simulacoes foram feitas por meio do simulador V-REP em associacao com a linguagem C++, utilizando um robo diferencial autonomo munido de sensores ultrassonicos. O experimento real fez uso de sensores e da placa Arduino acoplados ao chassi de um robo diferencial. Os resultados mostram que o objetivo e alcancado de forma satisfatoria por todas as tecnicas propostas.
Cerebral Oximetry Monitoring to Maintain Normal Cerebral Oxygen Saturation during High-risk Cardiac Surgery: A Randomized Controlled Feasibility Trial

Background:Cerebral oxygen desaturation during cardiac surgery has been associated with adverse perioperative outcomes. Before a large multicenter randomized controlled trial (RCT) on the impact of preventing desaturations on perioperative outcomes, the authors undertook a randomized prospective, parallel-arm, multicenter feasibility RCT to determine whether an intervention algorithm could prevent desaturations. Methods:Eight Canadian sites randomized 201 patients between April 2012 and October 2013. The primary outcome was the success rate of reversing cerebral desaturations below 10% relative to baseline in the intervention group. Anesthesiologists were blinded to the cerebral saturation values in the control group. Intensive care unit personnel were blinded to cerebral saturation values for both groups. Secondary outcomes included the area under the curve of cerebral desaturation load, enrolment rates, and a 30-day follow-up for adverse events. Results:Cerebral desaturations occurred in 71 (70%) of the 102 intervention group patients and 56 (57%) of the 99 control group patients (P = 0.04). Reversal was successful in 69 (97%) of the intervention group patients. The mean cerebral desaturation load (SD) in the operating room was smaller for intervention group patients compared with control group patients (104 [217] %.min vs. 398 [869] %.min, mean difference, −294; 95% CI, −562 to −26; P = 0.03). This was also true in the intensive care unit (P = 0.02). There were no differences in adverse events between the groups. Conclusions:Study sites were successful in reversal of desaturation, patient recruitment, randomization, and follow-up in cardiac surgery, supporting the feasibility of conducting a large multicenter RCT.
Hash‐bucket search: A fast technique for searching an english spelling dictionary

When a document is prepared using a computer system, it can be checked for spelling errors automatically and efficiently. This paper reviews and compares several methods for searching an English spelling dictionary. It also presents a new technique, hash‐bucket search, for searching a static table in general, and a dictionary in particular. Analysis shows that with only a small amount of space beyond that required to store the keys, the hash‐bucket search method has many advantages over existing methods. Experimental results with a sample dictionary using double hashing and the hash‐bucket techniques are presented.
Bioequivalence study of clopidogrel 75 Mg tablets in healthy male volunteers

The marked inter-individual and ethnic variabilities in the metabolism of clopidogrel has been investigated. Although the pharmacokinetics (PK) of clopidogrel has been reported previously in Whites and Korean volunteers, the PK characteristics may not be fully extrapolated to the Chinese population. Little is known about the PK characteristics and relative bioavailability of clopidogrel in Chinese population. The present study was to assess the PK characteristics and relative bioavailability of clopidogrel in healthy Chinese volunteers. A single-dose, randomized-sequence, open-label, 2-period crossover study was performed in fasting healthy Chinese male volunteers. Eligible subjects were randomly assigned to receive a single 75-mg dose of the test or reference formulation of clopidogrel, followed by a 1-week washout period and administration of the alternate formulation. The plasma samples were collected and at 0 min (baseline), as well as at 0.25, 0.5, 0.75, 1, 1.5, 2, 3, 4, 6, 8, 11, 14, 24 and 36 hours, respectively, after drug administration. The concentrations of both clopidogrel and SR26334 were detected by a validated liquid chromatography-tandem mass spectrometric method (LC-MS/MS). The formulations were considered to be bioequivalent if the 90% CIs for the log-transformed values were within the predetermined equivalence range (80%–125% for AUC and Cmax). For clopidogrel, the 90% CIs for the log-transformed ratios of Cmax and AUC0–t were 90.26%–113.91% and 91.82%–103.27%, respectively. For SR26334, the 90% CIs were 85.23%–112.97% and 93.11%–103.67%, respectively. In conclusion, the present results show that the formulation of clopidogrel was of bioequivalence to the reference, which have been tested in fasting, healthy, male Chinese volunteers.
Local and systemic responses induced by aphids in Solanum tuberosum plants

The aphids Macrosiphum euphorbiae (Thomas) and Myzus persicae (Sulzer) (Homoptera: Aphididae) are serious pests of potato (Solanum tuberosum L.) (Solanaceae), notably in transmitting several plant viruses. Heterospecific interactions may occur between these two species as they are often seen at the same time on the same potato plant in the field. As aphid infestation is known to induce both local and systemic changes, we conducted experiments to determine the effect of previous infestation on probing behaviour and feeding‐related parameters. We used the DC electrical penetration graph technique to characterize the influence of previous infestation by conspecific M. persicae or by heterospecific Ma. euphorbiae on M. persicae feeding behaviour at both local and systemic levels, i.e., on previously infested leaves and on non‐previously infested leaves of infested plants, respectively. Conspecific and heterospecific infestation led to similar modification of M. persicae feeding activities. However, the effects of previous infestation occurring at the local level were opposite to those observed at the systemic level. Myzus persicae food acceptance was slightly enhanced on previously infested leaves, whereas it was inhibited on non‐infested leaves of infested plants, which indicated an induced resistance mechanism. Our results advance the understanding of the mechanisms involved in aphid–host plant acceptance and colonization processes on potato plants in conspecific and heterospecific situations.