Miracle-dz/UniFAR-FTUs huggingface dataset:
Percutaneous Treatment of Lumbar Intervertebral Disk Hernias With Radiopaque Gelified Ethanol: A Preliminary Study

Study Design Prospective clinical trial. Objective Demonstrate the safety and efficacy of gelified ethanol in the percutaneous treatment of lumbar disk hernias. Summary of Background Data After the commercial withdrawal of Chymopapain, the need for new substances to treat intervertebral disk hernias was evident. Good results were obtained with pure ethanol, but this substance was difficult to handle. We decided to use a similar substance mixed with ethylcellulose to increase its viscosity and enhanced with radiopaque material. Methods Two hundred seventy-six consecutive patients sent to be treated of a lumbar intervertebral disk hernia percutaneously were included in this preliminary study and treated with radiopaque gelified ethanol (RGE) and intra-articular steroids. Three groups were set, group A for patients to be treated only with RGE and groups B and C for difficult cases presenting a narrow canal, foraminal hernia, or hiperalgic sleepless hernia, treated with RGE plus another intradiscal technique, automatized percutaneous diskectomy for group B and radiofrequency nucleoplasty for group C. Results Very good or good results were obtained in 202 (91.4%) of the 221 patients in group A. Of the 44 patients in group B, 37 patients (84%) presented very good or good results and in 9 (82%) of the 11 patients of group C, we obtained similar results. There was no allergic complication in any of our patients. Short-term follow-up with magnetic resonance showed little or no changes in the intervertebral disk but there was discordance with clinical signs. Long-term follow-up magnetic resonance showed a dramatic reduction in hernia volume. Conclusions This preliminary study shows the efficacy and inocuity of this new substance that could take over the Chymopapain therapeutic field.
Toxic shock syndrome toxin.

To the Editor. — While there is little doubt that toxic shock syndrome toxin-1 (TSST-1) is an important agent in the expression of toxic shock syndrome (TSS), the evidence presented by Garbe et al 1 for the role of additional toxin(s) is surely compelling. We also have noted that isolates of Staphylococcus aureus from nonmenstrual cases of TSS fall into two categories: (1) those from richly vascularized, hence oxygenated, superficial wounds and (2) those from deep sites of infection where low oxidation reduction potentials prevail. In our experience, TSST-1-producing strains seem to be associated with the former but not the latter. Since TSST-1 is expressed only aerobically, this observation is not unexpected. Several candidates for the title "TSST-2" have been suggested previously and must now await further study. More importantly, however, the findings of Garbe et al 1 raise a very perturbing issue. While the proportion of nonmenstrual cases of TSS
Detection technology of phishing

Phishing is a form of online identity theft. Phishers use social engineering to steal victims' personal identity data and financial account credentials. Social engineering schemes use spoofed e-mails to lure unsuspecting victims into counterfeit websites designed to trick recipients into divulging financial data such as credit card numbers, account usernames, passwords and social security numbers. In this paper, a thorough overview of a phishing attack and detection techniques is presented. Firstly, technologies used by phishers and the definition, classification and future works of deceptive phishing attacks are discussed. Following with the existing detection techniques in literatures and research-stage technologies are shown, and a thorough analysis that shortcomings of countermeasures is given.
Generic architecture for simulation of ADAS sensors

With rising complexity of advanced driver assistance systems (ADAS), development quality and speed are of increasing importance. Virtualization contributes towards this goal by providing a controlled environment even before hardware prototypes are available. One crucial component is a realistic description of the vehicle's sensors by means of sensor models. We propose a generic, modular architecture for the design of such models. The car's surroundings are represented by a list of objects that is modified during the virtualized sensing process. The result can then provide stimulation of ADAS function algorithms. Using the proposed architecture as a framework, we construct an exemplary model employing a stochastic variation of target object positions.
Analysis and Implementation of Time-delay Systems and Networked Control Systems

Systems with delays frequently appear in engineering. The presence of delays makes system analysis and control design much more complicated. Networked control systems where the delays are often random are typical cases of such systems. For one particular category of time-delays systems, integral processes with dead time (IPDTs), the control limits that a PI controller can achieve are discussed in this thesis. These limits include the region of the control parameters to guarantee the system stability, the control parameters to achieve the given gain and/or phase margins (GPMs), the constraint on achievable gain and phase margins, the performance of setpoint tracking and disturbance rejection. Three types of PI controllers, namely typical PI controller, single tuning-parameter PI controller and PI controller under two-degree-of-freedom (2-DOF) structure, are studied. In control schemes of the modified Smith predictor (MSP) where the controller usually includes a distributed delay, the system implementation is not trivial because of the inherent hidden unstable poles. This thesis provides an estimation of the minimal number of implementation steps for the distributed delay in linear control laws. This is obtained by solving an inequality with respect to the number of implementation steps. A coarse estimation is given as the initial value to solve the inequality using bisection algorithms. A minimization process as well as some other techniques are also introduced to further improve the estimation. In networked control systems, the network-transmission delay and data dropout are combinedly represented by a network-induced delay. By designing a data preprocessing mechanism, the network-induced delay can be assigned. Such delay assignment is applied to networked predictive control schemes, which alleviates system stability limits on the network-induced delay. Two stability criteria are given for the i
Design framework for a simple robotic ankle evaluation and rehabilitation device

This paper juxtaposes simple yet sufficiently general robotic mechanisms for ankle function evaluation, measurement and physiotherapy. For the choice, design and operation of the mechanism, a kinematics model of foot is adopted from biomechanics, based on the hypothesis that foot kinematics are similar to a 2R serial robot. We undertake experiments, using a 3D scanner and an inertial sensor in order to fully specify the design framework by studying a larger sample of healthy subjects. Our experimental analysis confirms and enhances the 2R foot model, and leads us to the choice of the specific mechanism. We compute the required workspace and thus address the issues required for a complete and efficient design. The robot must be capable to perform several multi-axis motions and sustain a significant range of forces and torques. We compare mechanisms based on serial and parallel robots, and choose a parallel tripod with an extra rotation axis for its simplicity, accuracy and generality.
Freud, Lacan e a terapêutica: considerações preliminares

EnglishThe following article aims to produce an examination on the relationship between the therapeutical element and psychoanalysis. It deals with the way psychoanalysis dialogues with the therapeutic practice in Freud´s work and how Lacan is positioned on the therapeutical issue and its effects on the analytic treatment. As a preliminary consideration on the subject the article locates therapy as a set of techniques and also approaches the notion of analyst´s desire as one of Lacan's strategies to deal with Freudian dilemmas facing the therapeutical expectations. portuguesO artigo a seguir pretende produzir um exame sobre as relacoes entre terapeutica e psicanalise. Aborda-se o modo como a psicanalise se constituiu em dialogo com as praticas terapeuticas em Freud e como Lacan se posiciona frente a terapeutica e seus efeitos no tratamento analitico. Enquanto consideracao preliminar sobre a questao, faz-se uma localizacao da terapeutica como um conjunto de tecnicas e verifica-se sobre a estrategia de Lacan via nocao de desejo do analista como um dos modos de lidar com os impasses freudianos frente a expectativa terapeutica.
Guidelines for the control of perinatally transmitted human immunodeficiency virus infection and care of infected mothers, infants and children.

T he transmission of the human immunodeficiency virus (HIV) from infected mothers to infants, either in utero or perinatally, has been well established. '-10 Infection in these infants can be asymptomatic or cause a variety of clinical syndromes including the acquired immunodeficiency syndrome (AIDS). ' It is not, however, conclusively known what proportion of infants exposed in utero or perinatally will become infected and in what proportion of infected infants clinical disease will develop. "2 As of December 1, 1985, there were 217 cases of pediatric AIDS reported to the Centers for Disease Control (CDC) (unpublished data). Of these children, 48% were born to intravenous-drug-using mothers, 17% to Haitians and 10% to mothers who either had AIDS or were sexual partners of men with AIDS or at risk for AIDS. An additional 39 (18 %) children were infected through transfusions of infected blood or blood products, and 13 (6%) had unknown sources of infection. Thus, 165 (76%) of the cases had been exposed to HIV in utero or perinatally.
La superioridad de los economistas

Este articulo examina la posicion dominante de la economia en la red de ciencias sociales en Estados Unidos. Primero documenta su insularidad relativa usando datos bibliometricos y luego analiza el rigido control desde arriba que le da su estructura jerarquica caracteristica. Los economistas tambien se distinguen de otros cientificos sociales por su mejor situacion material, su vision del mundo mas individualista y su confianza en la disciplina para resolver los problemas de mundo. Estas caracteristicas constituyen lo que aqui se llama la superioridad de los economistas, cuya supremacia objetiva esta ligada intimamente a la sensacion subjetiva de tener autoridad y derecho a ella. Esa superioridad alienta su intervencion practica y su gran influencia en la economia, pero tambien los expone a conflictos de interes, a la critica politica e incluso al ridiculo.
Coupling Whispering-Gallery-Mode Microcavities With Modal Coupling Mechanism

We theoretically describe and study coupling between two whispering-gallery-mode microcavities through a side coupled fiber taper. The two microcavities can couple to each other bidirectionally with only one fiber taper waveguide due to the modal coupling between a pair of whispering-gallery modes traveling in opposite directions. By choosing appropriate physical parameters, some interesting spectra, such as electromagnetically-induced transparency-like coherent transmission and band-like reflection, can be obtained in such a system. Slow light is discussed in this paper as a direct application of the coupled microresonator structure. This structure also has potential application in coupled cavity quantum electrodynamics.
Regulation of Neurotrophin Mammalian Visual System Receptors Maturation

‘Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, ‘Neurosciences Program, Stanford University School of Medicine, Stanford, California 94305, 3Department of Neuroscience, Genentech, Inc., South San Francisco, California 94080, and 4Eukaryotic Signal Transduction Group, MMCL, ABL-Basic Research Program. National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, Maryland 21702
Efficacy and Safety of Tenecteplase in Combination With the Low-Molecular-Weight Heparin Enoxaparin or Unfractionated Heparin in the Prehospital Setting: The Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT)-3 PLUS Randomized Trial in Acute Myocardial Infarction

Background—The combination of a single-bolus fibrinolytic and a low-molecular-weight heparin may facilitate prehospital reperfusion and further improve clinical outcome in patients with ST-elevation myocardial infarction. Methods and Results—In the prehospital setting, 1639 patients with ST-elevation myocardial infarction were randomly assigned to treatment with tenecteplase and either (1) intravenous bolus of 30 mg enoxaparin (ENOX) followed by 1 mg/kg subcutaneously BID for a maximum of 7 days or (2) weight-adjusted unfractionated heparin (UFH) for 48 hours. The median treatment delay was 115 minutes after symptom onset (53% within 2 hours). ENOX tended to reduce the composite of 30-day mortality or in-hospital reinfarction, or in-hospital refractory ischemia to 14.2% versus 17.4% for UFH (P =0.080), although there was no difference for this composite end point plus in-hospital intracranial hemorrhage or major bleeding (18.3% versus 20.3%, P =0.30). Correspondingly, there were reductions in in-hospital reinfarction (3.5% versus 5.8%, P =0.028) and refractory ischemia (4.4% versus 6.5%, P =0.067) but increases in total stroke (2.9% versus 1.3%, P =0.026) and intracranial hemorrhage (2.20% versus 0.97%, P =0.047). The increase in intracranial hemorrhage was seen in patients >75 years of age. Conclusions—Prehospital fibrinolysis allows 53% of patients to receive reperfusion treatment within 2 hours after symptom onset. The combination of tenecteplase with ENOX reduces early ischemic events, but lower doses of ENOX need to be tested in elderly patients. At present, therefore, tenecteplase and UFH are recommended as the routine pharmacological reperfusion treatment in the prehospital setting.
Stock Prediction via Sentiment and Online Social Status

Studies of stock market prediction show that stock movements are related to the sentiment of social media. However, few studies have investigated the role of online social relations in predicting stock movements. This paper aims at constructing features that capture users’ online social status and incorporating these into stock prediction models. Online opinions are often developed through interactions and are weaker in their early stages. We developed a feature-enhancing procedure motivated by statistical surveillance approaches to strengthen the ability to capture emerging trends. We evaluated our feature-enhancing procedure by developing models to predict stock returns in the following 20-minute period. A comparison of experimental results with baseline models shows that our feature-enhancing design helped to predict stock movements. The model (SE_CUSUM) that adopted features enhanced by cumulative sum (CUSUM), a statistical surveillance approach, performed better than baseline models in terms of directional accuracy, balanced error rate, root mean square error, and mean absolute error. Our simulated trading also showed that SE_CUSUM realized a higher profit than the baseline approaches. These results suggest that incorporating online social status and our feature-enhancing procedure improve high frequency stock prediction performance.
Synthesis and anti-tumour activities of sulphated polysaccharide obtained from Momordica charantia

A native polysaccharide (MCP2) was extracted and isolated from Momordica charantia. Four sulphated derivatives of MCP2 were prepared by chlorosulphonic acid method. The structures of the sulphated derivatives were characterised by FT-IR spectra. Depending on the reaction conditions, the sulphated derivatives showed different degree of substitution (DS) ranging from 0.56 to 1.10, and different weight-average molecular mass (Mw) ranging from 7.2 to 9.3 KDa. It implied the efficient substitution of hydroxyl groups in the polysaccharides by sulphated groups with degradation. The effects of the sulphated derivatives on inhibiting the growth of HepG2 cells and Hela cells in vitro were compared with taking non-modified MCP2 as control. The sulphated derivatives inhibited the growth of HepG2 cells and Hela cells in vitro significantly, which indicated that sulphated modification could enhance the anti-tumour activity of MCP2.
Bimodal perception of spectrum compressed speech

The results of both normal-hearing and profoundly hearing-impaired adults, tested with spectrum-compressed speech via a modified chirp-z algorithm with and without visual stimuli, are reported. Ten normal-hearing adult listeners and three profoundly hearing-impaired adult listeners were asked to identify nonsense syllables presented auditorily and bimodally (audition and vision) via video tape under two conditions: low-pass filtered or unprocessed, and spectrum-compressed. The low-pass filtered and spectrum-compressed speech occupies the same spectral width of 840 Hz; at 900 Hz and above, the attenuation is at least 60 dB. The spectrum compression is performed by means of a modified chirp-z algorithm, and the test results are significant.
Empirical Evidence Supporting the Conceptual Relatedness of Object Representations and Internal Working Models

The proliferation of new developmental and clinical theories broadly termed “psychoanalytic” demands a methodology for making systematic comparisons to establish the commonalities and distinctions among them. This article presents an empirical method for the comparative evaluation of such theories. The Mother-To-Child Object Representation / Internal Working Model Q-sort is a 100-item instrument constructed to assess the quality of the prototypical mother's object representation and internal working model of her child at age five. Object relations judges were asked to sort these items for a complex, differentiated, integrated object representation of a five-year-old, attachment judges for a secure, coherent, freely valuing internal working model of a five-year-old. Judges' criterion Q-sorts in each group yielded a composite criterion Q-sort of the quality of the prototypical mother's mental representation of her child according to each group's theoretical perspective. The Spearman-Brown correlation between the two composite criterion Q-sorts was r = . 90, p < . 001, suggesting that when confined to a 100-item common vocabulary, judges representing each theoretical construct agreed on the conceptual relatedness of object representations and internal working models. The theoretical constructs of object representations and internal working models share common assumptions in need of further exploration.
A Dynamic Game under Ambiguity: Repeated Bargaining with Interactive Learning

Conventional Bayesian games of incomplete information are limited in their ability to represent complete ignorance of an uninformed player about an opponent's private information. Using an illustrative example of repeated bargaining with interactive learning, we analyze a dynamic game of incomplete information that incorporates a multiple-prior belief system. We consider a game in which a principal sequentially compensates an agent for his effort on a novel experiment --- a Poisson process with unknown hazard rate. The agent has knowledge to form a single prior over the hazard rate, but the principal has complete ignorance, represented by the set of all plausible prior distributions over the hazard rate. We propose a new equilibrium concept --- Perfect Objectivist Equilibrium --- in which the principal infers the agent's prior from the observed history of the game via maximum likelihood updating. The new equilibrium concept embodies a novel model of learning under ambiguity in the context of a dynamic game. The unique (Markov) equilibrium outcome determines a unique bargaining solution. The underlying Markov Perfect Objectivist Equilibria are all belief-free, in sharp contrast to Markov Perfect Bayesian Equilibria, which hinge on subjective pretense of knowledge and predict a continuum of equilibrium outcomes.
Contributions à la gestion optimale de capteurs : application à la tenue de situations aériennes

Soit un ensemble d'avions et de cibles se trouvant dans un espace aerien. L'objectif de ces avions est de surveiller cet espace, en particulier les cibles, afin d'elaborer les manœuvres a effectuer pour parer la menace que celles-ci peuvent representer. Cette mission peut etre decomposee en trois etapes : detection, estimation et identification. Chaque avion est equipe d'un ou plusieurs capteurs heterogenes de type radar et/ ou optronique. Ces capteurs ne peuvent observer instantanement qu'une petite partie de l'espace leur faisant face. Il est alors necessaire de reorienter leurs axes de visee afin d'observer la totalite de l'espace d'interet. Nous etudions ici la detection. Nous nous interessons a la gestion de ces capteurs, i. E. a la problematique quel(s) capteur(s) observe(nt) quelle(s) cible(s), a quel moment et dans quelles conditions? Nous presentons, essentiellement des resultats analytiques. Apres avoir modelise les fonctions elementaires de detection de chacun des capteurs, nous proposons, pour les capteurs de type radar dans un environnement monocible, une optimisation de leurs probabilites de detection par une decomposition en detections elementaires. Nous placant ensuite dans un contexte monocapteur multicible, nous etablissons une methode optimale d'allocation des ressources temporelles pour la detection des cibles et ce, pour plusieurs niveaux de connaissance a priori. Les resultats sont bases sur des methodes de programmation non lineaire et sont rapproches de ceux obtenus en theorie de la recherche. Enfin, nous proposons dans un contexte multicapteur multicible une methode de planification de l'utilisation des capteurs pour l'observation des cibles. Le critere de selection considere est compare avec les criteres entropiques utilises en estimation.
Philosophical Profiles: Essays in a Pragmatic Mode

Philosophical Profiles brings together ten important essays by Richard Berstein. Each focuses on the work of a thinker or group of thinkers at the center of contemporary developments in philosophy, including Hannah Arendt, John Dewey, Hans-Georg Gadamer, Jurgen Habermas, G.W. F. Hegel, Alasdair MacIntyre, Herbert Marcuse, and Richard Rorty.
Ultra-wideband millimeter-wave bowtie antenna

We present an ultra-wideband antenna for mm-wave applications. The antenna consists of a bowtie patch integrated with the feeding network. The feeding network is implemented as a multilayer substrate structure. The differential excitation of the bowtie is performed in a similar way to Magneto-Electric Dipoles and Marchand baluns. The simulated antenna shows a relative bandwidth of 2.6 : 1 with a reflection coefficient better than −8 dB. The radiation pattern remains fairly stable over 20–50 GHz with a boresight directivity of 5.8–8.3 dBi.
Antimicrobial Susceptibility Testing, Drug Resistance Mechanisms, and Therapy of Infections with Nontuberculous Mycobacteria

SUMMARY Within the past 10 years, treatment and diagnostic guidelines for nontuberculous mycobacteria have been recommended by the American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA). Moreover, the Clinical and Laboratory Standards Institute (CLSI) has published and recently (in 2011) updated recommendations including suggested antimicrobial and susceptibility breakpoints. The CLSI has also recommended the broth microdilution method as the gold standard for laboratories performing antimicrobial susceptibility testing of nontuberculous mycobacteria. This article reviews the laboratory, diagnostic, and treatment guidelines together with established and probable drug resistance mechanisms of the nontuberculous mycobacteria.