Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis and Optimization of the Efficiency of Induction Heating Applications With Litz-Wire Planar and Solenoidal Coils

Optimization of the efficiency of an induction heating application is essential in order to improve both reliability and performance. For this purpose, multistranded cables with litz structure are often used in induction heating applications. This paper presents an analysis and optimization of the efficiency of induction heating systems focusing on the optimal copper volume of the winding with respect to different constraints. The analysis is based on the concept of a one-strand one-turn coil, which captures the dissipative effects of an induction heating system and reduces the number of variables of the analysis. An expression for the efficiency of the induction heating system is derived. It is found that, with the geometry and the other parameters of the system fixed, efficiency depends on the copper volume of the windings. In order to use this result to optimize the efficiency of an application, volume restrictions, the packing factor and the window utilization factor are also considered. The optimum frequency for an induction heating system is also studied in this study. An experimental verification for both planar and solenoidal cases is also presented.
Experimental evaluation of wide range injection locking in a CMOS RC oscillator

CMOS RC oscillators have low area, can be built with a low cost technology, and have a wide tuning range, but they have higher phase-noise than LC oscillators. This can be overcome by synchronizing the oscillator by injection-locking with an low phase-noise external source. We present here an experimental study of injection-locking in an RC two-integrator oscillator. First and second harmonic injection in different locations of the oscillator are investigated. A test circuit was fabricated using a standard CMOS technology with 1.2 V supply. Measurement results show that a phase noise improvement of more than 30 dB, can be obtained with only -30 dBm injected signal between 100 kHz and 10 MHz frequency offset over a wide frequency range (600 MHz to 3 GHz).
Analog performance investigation of double gate junctionless transistor using spacer layer engineering

In this paper, we determine the impact of high-k and low-k spacer and gate dielectric stack on analog performance of double gate junctionless transistor (DG-JLT). The various combinations of gate dielectric stack is formed by atomic deposition of 0.6 nm SiO2 followed by 0.8 nm Si3N4, 0.6 nm SiO2 followed by 2.3 nm HfO2, 0.6 nm SiO2 followed by 4.1 nm TiO2 to attain capacitive effective thickness (CET) of 1 nm. The characteristics are revealed through extensive device simulations and compared with other DG-JLT, by taking all possible combinations of gate dielectric stack of CET of 1 nm. The proposed DG-JLT of gate dielectric stack SiO2 followed by TiO2 gives superior performance in comparision to other combinations. It shows superior drain current with low short channel effects having subthreshold swing (SS) of 61.46 mV/dec & drain induced barrier lowering (DIBL) of 7 mV/V. Our findings also reveal improvement in peak transconductance at the cost of decrease in unity gain cut-off frequency due to high gate capacitance.
Improving software testing process: feature prioritization to make winners of success‐critical stakeholders

For a successful software project, acceptable quality must be achieved within an acceptable cost, demonstrating business value to customers and satisfactorily meeting delivery timeliness. Testing serves as the most widely used approaches to determine that the intended functionalities are performed correctly and achieve the desired level of services; however, it is also a labor‐intensive and expensive process during the whole software life cycle. Most current testing processes are often technique‐centered, rather than organized to maximize business value. In this article, we extend and elaborate the ‘4+1’ theoretical lenses of Value‐based Software Engineering (VBSE) framework in the software testing process; propose a multi‐objective feature prioritization strategy for testing planning and controlling, which aligns the internal testing process with value objectives coming from customers and markets. Our case study in a real‐life business project shows that this method allows reasoning about the software testing process in different dimensions: it helps to manage the testing process effectively and efficiently, provides information for continuous internal software process improvement, and increases customer satisfaction, which makes winners of all success‐critical stakeholders (SCSs) in the software testing process. Copyright © 2010 John Wiley & Sons, Ltd.
Changes in liver function parameters after occlusion of gastrorenal shunts with balloon-occluded retrograde transvenous obliteration.

OBJECTIVE AND METHODS To evaluate the effects of portal blood flow on liver function, this pilot study investigated the correlation between changes in portal blood flow as measured by image-directed Doppler ultrasonography and liver function tests in nine patients with cirrhosis who were treated with balloon-occluded retrograde transvenous obliteration. All patients had large gastric varices and prominent gastrorenal shunts. RESULTS Treatment caused a significant increase (p < 0.01) in portal blood flow; we documented reversion from hepatofugal to hepatopetal portal flow in one patient and increases in hepatopetal flow from 5.4 +/- 1.1 to 7.85 +/- 1.4 cm/s (mean +/- SD) in eight patients. All patients showed decreases in gastric variceal size. However, portal pressure rose significantly in all patients after treatment from 25.4 +/- 7.6 to 30.7 +/- 5.8 mmH2O (n = 7, mean +/- SD), and two of nine patients had worsening of esophageal varices. All nine patients showed improvement in the 15-min retention rate of indocyanine green from 31.8 +/- 16.1 to 21.8 +/- 12.4% (mean +/- SD, p < 0.01), whereas seven patients showed increased serum albumin levels after treatment. CONCLUSIONS These results suggest balloon-occluded retrograde transvenous obliteration increases hepatic portal blood flow, which may be accompanied by improvements in liver function.
A Novel Approach for Testing an Aspect Oriented Software System Using Prioritized-Genetic Algorithm (P-GA)

Nowadays, Unified Modeling Language (UML) has been extensively used in the area of software testing. Aspect Oriented Programming (AOP) paradigm is relatively a new field of software development. Testing an AOP is still in its infancy stage. In addition, dealing with aspects in AOP is an intractable problem. Furthermore, there is no work based on optimization for test data generation. In this paper, aspect integrated UML activity diagram has been used for generation of optimal and minimal test case scenarios by applying genetic algorithm (GA) in order to obtain full aspectual coverage criteria. Moreover, this paper also discusses the comparison of P-GA (proposed approach) with other contemporary testing techniques that demonstrate the effectiveness of the proposed approach.
Innovative antibacterial drugs: nothing ventured, nothing gained

The current paradox of the widespread clinical demand for novel anti-bacterial drugs and lack of commensurate industrial research activity is unprecedented in modern drug discovery. Although the root causes of the pharmaceutical industry’s disengagement from antibacterial drug discovery have been discussed at length and attributed largely to a lack of productivity coupled with pharmacoeconomic and regulatory considerations, the challenges faced by privately held biotech companies in addressing this therapeutic need originate from the conflict between the capital intensive nature of early-stage drug discovery and the current venture capital funding paradigm. Continued innovation of antibacterial drugs will require a fundamental shift in how discovery through preclinical research is supported.
Social Behavior Analysis of VoIP Users and its application to Malicious Users Detection (Extended Version { V1.0)

IP Telephony has become very popular and Session Initiation Protocol (SIP)-based telephony systems are almost substituting the traditional PSTN systems. Being so widespread and ubiquitous, the protocol’s resilience and security in presence of incorrect, malformed or malicious messages is fundamental for the correct management of a network. This is of particular importance for the session-based applications since they appear to be much more sensitive very sensitive not only to malicious attacks, but also to errors, and even incorrect interpretation of the standard. To have an in-depth knowledge about the net-work behavior is primary requirement to design and tune any attack or anomaly detection system. In the context of VoIP, traffic analysis plays a very significant role due to the fact that SIP based VoIP traffic does not follow any generic model to describe its characteristics like traditional telephony. To this end, we have performed a thorough analysis on SIP traces captured from the VoIP network of our institution. Here, we use social network analysis techniques to capture the relationship behavior of users and to explore distinct behavioral patterns of users inside the VoIP network. Knowledge about the normal behavior of the system and users gained from the traffic analysis is helpful in detecting intrusion and anomalies. In this paper, we also present an anomaly detection architecture where we train an automated machine with the normal behavioral pattern of the users. The machine, thus trained, is capable of identifying malicious users.
Sistemas de gestión de la calidad en las empresas portuguesas: implantación, impacto y rendimiento

Reconocer la importancia de la Calidad y de la Gestion de la Calidad Total (Total Quality Management - TQM), desde un punto de vista estrategico, para la competitividad en un mercado global, ha sido, sin duda, lo mas importante cambio que han experimentado las organizaciones europeas y americanas en los ultimos 20 anos. Son cada vez mas las empresas que intentan llegar a un mayor nivel competitivo, superando a sus competidores, al garantizar la regularidad y la mejora de la calidad de sus productos y procesos a traves de la certificacion ISO 9000. La investigacion empirica que presentamos busca determinar que es lo que motiva las empresas portuguesas a obtener sistemas de certificacion y aseguramiento de la calidad, asi como sus ventajas o beneficios y los problemas asociados que son capaces de soportar. Sin embargo, los procesos por los cuales se disena e implementa la Gestion de la Calidad Total no son suficientemente conocidos para llegar a determinar cuales son las mejores practicas o los factores que influyen en el exito y en el logro de resultados. El objetivo principal de este trabajo es crear y validar un modelo de relaciones entre las variables cruciales para el exito de la aplicacion de la Gestion de la Calidad Total, que sirva de referencia para las empresas portuguesas para evaluar y mejorar la calidad de la gestion y de los resultados o rendimiento. Este modelo define la calidad como una variable cultural, y establece vinculos entre la estrategia de aplicacion del sistema de gestion de calidad, los impactos sobre la estructura y los factores de aplicacion de TQM, asi como sus implicaciones sobre la renta.
Added value of involving patients in the first step of multidisciplinary guideline development: a qualitative interview study among infertile patients.

BACKGROUND Patient involvement in scoping the guideline is emphasized, but published initiatives actively involving patients are generally limited to the writing and reviewing phase. OBJECTIVE To assess patients' added value to the scoping phase of a multidisciplinary guideline on infertility. DESIGN Qualitative interview study. SETTING AND PARTICIPANTS We conducted interviews among 12 infertile couples and 17 professionals. INTERVENTION We listed and compared the couples' and professionals' key clinical issues (=care aspects that need improvement) to be addressed in the guideline according to four domains: current guidelines, professionals, patients and organization of care. MAIN OUTCOME MEASURES Main key clinical issues suggested by more than three quarters of the infertile couples and/or at least two professionals were identified and compared. RESULTS Overall, we identified 32 key clinical issues among infertile couples and 23 among professionals. Of the defined main key clinical issues, infertile couples mentioned eight issues that were not mentioned by the professionals. These main key clinical issues mainly concerned patient-centred (e.g. poor information provision and poor alignment of care) aspects of care on the professional and organizational domain. Both groups mentioned two main key clinical issues collectively that were interpreted differently: the lack of emotional support and respect for patients' values. CONCLUSIONS Including patients from the first phase of the guideline development process leads to valuable additional main key clinical issues for the next step of a multidisciplinary guideline development process and broadens the scope of the guideline, particularly regarding patient-centredness and organizational issues from a patients' perspective.
Kinematic Analysis of Virtual Reality Task Intensity Induced by a Rehabilitation Robotic System in Stroke Patients

Robotic systems provide a paradigm shift in maximizing neural plasticity as part of human motor control recovery following stroke. Such a system shifts the treatment from therapist dependent to patient dependent by its potential to increase the treatment dose and intensity, as long as the patient can tolerate it. The experimental protocol included 10 post stroke hemiparetic subjects in a chronic stage. Subjects were treated with an upper limb exoskeleton system (EXO-UL7) using a unilateral mode, and a bilateral mode. Seven virtual reality tasks were utilized in the protocol. A kinematic-based methodology was used to study the intensity of the virtual reality tasks in each one of the operational modes. The proposed method is well suited for early evaluation of a given virtual reality task, or movement assistance modality during the development process. Pilot study data were analyzed using the proposed methodology. This allowed for the identification of kinetic differences between the assistance modalities by assessing the intensity of the virtual reality tasks.Copyright © 2013 by ASME
Human Serum Amyloid P Component cDNA ISOLATION

Complementary DNA clones corresponding to the human serum amyloid P component (SAP) were isolated, and the complete nucleotide and derived amino acid sequence of preSAP was determined. PreSAP biosynthesis is directed by a 1.1-kilobase mRNA. Synthesis and postsynthetic processing of preSAP in Xenopus oocytes result in secretion of a protein with mobility similar to native purified SAP when analyzed by sodium dodecyl sulfate gel electrophoresis. The human SAP gene is on chromosome 1, probably closely linked to the gene for C-reactive protein which encodes the related acute phase reactant found in human plasma.
A Phase I Dosing Study of Ferumoxytol for MR Lymphography at 3 T in Patients With Prostate Cancer.

OBJECTIVE The objective of our study was to determine the optimal dose of ferumoxytol for performing MR lymphography (MRL) at 3 T in patients with prostate cancer. SUBJECTS AND METHODS This phase I trial enrolled patients undergoing radical prostatectomy (RP) with bilateral pelvic lymph node dissection (PLND). Three groups of five patients each (total of 15 patients) received IV ferumoxytol before RP with bilateral PLND at each of the following doses of iron: 4, 6, and 7.5 mg Fe/kg. Patients underwent abdominopelvic MRI at 3 T before and 24 hours after ferumoxytol injection using T2- and T2*-weighted sequences. Normalized signal intensity (SI) and normalized SD changes from baseline to 24 hours after injection within visible lymph nodes were calculated for each dose level. Linear mixed effects models were used to estimate the effects of dose on the percentage SI change and log-transformed SD change within visible lymph nodes to determine the optimal dose of ferumoxytol for achieving uniform low SI in normal nodes. RESULTS One patient who was excluded from the study group had a mild allergic reaction requiring treatment after approximately 2.5 mg Fe/kg ferumoxytol injection whereupon the injection was interrupted. The 15 study group patients tolerated ferumoxytol at all dose levels. The mean percentage SI change in 13 patients with no evidence of lymph metastasis was -36.4%, -45.4%, and -65.1% for 4, 6, and 7.5 mg Fe/kg doses, respectively (p = 0.041). CONCLUSION A dose level of 7.5 mg Fe/kg ferumoxytol was safe and effective in deenhancing benign lymph nodes. This dose therefore can be the starting point for future phase II studies regarding the efficacy of ferumoxytol for MRL.
Prevalence of obesity in Canada

Excess weight represents a critical and common health problem in Canada. The last survey of a national representative sample based on measured anthropometrics has been conducted in 1992. According to surveys using measured data, the prevalence of obesity (body mass index, BMI = 30.0 kg m−2) between 1970 and 1992 for those aged 20–69 years increased from 8% to 13% in men and 13% to 15% in women. The proportion of Canadians displaying a BMI ≥25.0 kg m−2 increased from 47% to 58% in men and from 34% to 41% in women in the same period. The most recent prevalence estimates from self‐reported data in a national representative sample indicated that 15% of the adult population (≥18 years) was affected by obesity, while an additional 33% was classified in the overweight category (BMI 25.0–29.9 kg m−2) in 2003. However, it has been suggested that self‐reported height and weight underestimate the prevalence of obesity by approximately 10%. Canadian children, aboriginal populations, and immigrants are some of the vulnerable groups particularly at risk of excess weight or for which the increase in the recent decades has been greater than the national increase. The increases in overweight and obesity over the past 30 years among Canadians have been dramatic. It will be possible to precisely analyse the current situation and its evolution in the last 10 years when data based on measured height and weight will be released, that is, in 2005 and after.
Real-Time Traffic Light Recognition Based on Smartphone Platforms

Traffic light recognition is of great significance for driver assistance or autonomous driving. In this paper, a traffic light recognition system based on smartphone platforms is proposed. First, an ellipsoid geometry threshold model in Hue Saturation Lightness color space is built to extract interesting color regions. These regions are further screened with a postprocessing step to obtain candidate regions that satisfy both color and brightness conditions. Second, a new kernel function is proposed to effectively combine two heterogeneous features, histograms of oriented gradients and local binary pattern, which is used to describe the candidate regions of traffic light. A kernel extreme learning machine (K-ELM) is designed to validate these candidate regions and simultaneously recognize the phase and type of traffic lights. Furthermore, a spatial-temporal analysis framework based on a finite-state machine is introduced to enhance the reliability of the recognition of the phase and type of traffic light. Finally, a prototype of the proposed system is implemented on a Samsung Note 3 smartphone. To achieve a real-time computational performance of the proposed K-ELM, a CPU-GPU fusion-based approach is adopted to accelerate the execution. The experimental results on different road environments show that the proposed system can recognize traffic lights accurately and rapidly.
An Abstract Formalization of Correct Schemas for Program Synthesis

Program schemas should capture not only structured program design principles, but also domain knowledge, both of which are of crucial importance for hierarchical program synthesis. However, most researchers represent schemas as purely syntactic constructs, which can provide only a program template, but not the domain knowledge. In this paper, we take a semantic approach and show that a schema S consists of a syntactic part, namely a template T, and a semantic part. Template T is formalized as an open (first-order) logic program in the context of the problem domain, characterized as a first-order axiomatization, called a specification frameworkF, which is the semantic part. F endows the schema S with a formal semantics, and enables us to define and reason about its correctness. Naturally, correct schemas can be used to guide the synthesis of correct programs.
Ligand migration in the truncated hemoglobin of Mycobacterium tuberculosis

The truncated hemoglobin of Mycobacterium tuberculosis (Mt‐trHbO) is a small heme protein belonging to the hemoglobin superfamily. Truncated hemoglobins (trHbs) are believed to have functional roles such as terminal oxidases and oxygen sensors involved in the response to oxidative and nitrosative stress, nitric oxide (NO) detoxification, O2/NO chemistry, O2 delivery under hypoxic conditions, and long‐term ligand storage. Based on sequence similarities, they are classified into three groups. Experimental studies revealed that all trHbs display a 2‐on‐2 α‐helical sandwich fold rather than the 3‐on‐3 α‐helical sandwich fold of the classical hemoglobin fold. Using locally enhanced sampling (LESMD) molecular dynamics, the ligand‐binding escape pathways from the distal heme binding cavity of Mt‐trHbO were determined to better understand how this protein functions. The importance of specific residues, such as the group II and III invariant W(G8) residue, can be seen in terms of ligand diffusion pathways and ligand dynamics. LESMD simulations show that the wild‐type Mt‐trHbO has three diffusion pathways while the W(G8)F Mt‐trHbO mutant has only two. The W(G8) residue plays a critical role in ligand binding and stabilization and helps regulate the rate of ligand escape from the distal heme pocket. Thus, this invariant residue is important in creating ligand diffusion pathways and possibly in the enzymatic functions of this protein. © 2011 IUBMB IUBMB Life, 63(3): 214–220, 2011
The evolution of strategy.

What do you do to start reading the evolution of strategy? Searching the book that you love to read first or find an interesting book that will make you want to read? Everybody has difference with their reason of reading a book. Actuary, reading habit must be from earlier. Many people may be love to read, but not a book. It's not fault. Someone will be bored to open the thick book with small words to read. In more, this is the real condition. So do happen probably with this the evolution of strategy.