Miracle-dz/UniFAR-FTUs huggingface dataset:
Chromatographic methods for isolation and characterization of bioactive molecules from medicinal plant Mesua ferrea Linn

Partially purified fraction of methanol extract of leaf of Mesua ferrea Linn was assessed for its phytochemical screening. Thin layer chromatographic studies, antimicrobial activity, anti-inflammatory activity, antidiabetic activity and antioxidant activity experiments were conducted. Phytochemical screening reflects the presence of alkaloids, flavonoids, coumarins, terpenoids, steroids, emodins and quinone derivatives. Thin layer chromatographic study was carried out using solvent system of various polarities of n-butanol, acetic acid and acetone. TLC profiling shows pure band of peptide at 254 and 366 nm. Protein content was determined using Nanodrop technique. Antimicrobial efficiency was determined using well diffusion method. Partially purified fractions of Mesua ferrea Linn was most sensitive against Staphylococcus aureus, Pseudomonas aeruginosa and Protease mirabilis with maximum zone of inhibition in diameter 16, 21 and 17 mm respectively at a concentration of 20 µg. In vitro anti-inflammatory activity was evaluated using albumin denaturation (84.67%) membrane stabilization assay (73.6%) and proteinase inhibitory activity (90.62%). Aspirin was used as standard drug for the study of anti-inflammatory activity. In vitro antidiabetic activity was determined by α-amylase inhibition assay. Antioxidant activity was performed by reducing power assay. Fraction #3 has higher absorbance 0.94 at 500 µg/ml followed by fraction #2 absorbance 0.89 at 500 µg/ml.
Dropping Impact Characteristics Analysis of a Cubic Nonlinear Packaging System with a Cantilever Beam Type Elastic Critical Component with Concentrated Tip Mass

A mathematical model for a cubic nonlinear packaging system with a cantilever beam type critical component with concentrated tip mass is proposed. The finite element method and the implicit finite difference method together with the Rung-Kutta method are applied to study the dropping impact dynamics of the critical component and the effect of system parameters, such as the value of the concentrated tip mass and the frequency of the main component, is discussed. The results show that the relative displacement and acceleration change remarkably with the length of the cantilever beam, and the maximum internal stress occurs at the joint end of the critical component. With the increase of the value of the concentrated tip mass and/or a higher frequency of the main component, the amplitudes of the responses increase obviously.
Effect of nickel oxide nanoparticles on dielectric and optical properties of nematic liquid crystal

In the present paper, we have studied the improvement in dielectric and optical properties of nematic liquid crystal (NLC) by doping of nickel oxide (NiO) nanoparticles. We have observed the dielectric and optical properties of pure and doped cells in order to understand the influence of NiO nanoparticles in the pure NLC. The experimental results have been analyzed through dielectric spectroscopic and optical texural methods.Detailed studies of dielectric parameters such as dielectric permittivity, dielectric loss and dielectric loss factor as a function of frequency with temperature were carried out. It has been observed that on doping the nanoparticles in NLC, the value of dielectric parameters (dielectric permittivity, dielectric loss and dielectric loss factor) decreases. The impedance and resistance of both pure and nanoparticles doped NLC cells were studied and found that for doped NLC, these parameter have low value. In addition to this, optical textures of the pure and doped samples have also been observed with a polarizing optical microscope at room temperature. All the results i.e. related to the investigation of dielectric and electro-optic properties have been explained by using existing theory of NLC.In the present paper, we have studied the improvement in dielectric and optical properties of nematic liquid crystal (NLC) by doping of nickel oxide (NiO) nanoparticles. We have observed the dielectric and optical properties of pure and doped cells in order to understand the influence of NiO nanoparticles in the pure NLC. The experimental results have been analyzed through dielectric spectroscopic and optical texural methods.Detailed studies of dielectric parameters such as dielectric permittivity, dielectric loss and dielectric loss factor as a function of frequency with temperature were carried out. It has been observed that on doping the nanoparticles in NLC, the value of dielectric parameters (dielectric permittivity, dielectric loss and dielectric loss factor) decreases. The impedance and resistance of both pure and nanoparticles doped NLC cells were studied and found that for doped NLC, these parameter have low value. In addition to this, optical textures of the pure and doped samples have also been.
ublic sector innovation — From theory to measurement

While there is growing awareness that much innovation currently takes place in the public sector, it is also recognised that more systematic efforts to promote innovation are needed to address the economic and societal challenges that public sectors face. However, there is a lack of a common understanding of what public sector innovation is and a lack of a measurement framework that can shed light on innovation processes in public sector organisations. Based on insights generated in a recent Nordic pilot study, this paper seeks to contribute to eywords:
Safety and efficacy of Iranian rFVIII

1. Pediatric Congenital Hematologic Disorders Research Center, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Baqiyatallah University of Medical Sciences, Tehran, Iran 3. Zahedan University of Medical Sciences, Zahedan, Iran 4. Comprehensive Care Center for Children with Hemophilia, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
IMPACT OF A PHARMACIST-LED EDUCATIONAL INTERVENTION ON QUALITY OF LIFE AMONG PATIENTS WITH ASTHMA

Objectives: Asthma is a chronic disease resulting in reduced quality of life (QoL) of most affected individuals. Training in asthma-related knowledge, inhaler skills, medicine usage, and the prevention of adverse drug events is demonstrated to improve asthma patients’ QoL. Therefore, the research was conducted to evaluate the effectiveness of education intervention undertaken by pharmacists on QoL of patients with asthma. Methods: We conducted a clinical randomized controlled trial among asthmatic outpatients aged 18 years or older in the Department of Screening Respiratory Function, University Medical Center, Ho Chi Minh City, Vietnam. Patients were randomized into an intervention group (IG) and a non-IG (NIG). The clinical pharmacists’ intervention program included training in asthma-related knowledge, inhaler technique, recognition, prevention of adverse drug events, and lifestyle adjustment. Participant screening was conducted using the telephone on a monthly basis. QoL was measured using the Vietnamese Version of the Mini Asthma QoL Questionnaire (MiniAQLQ). The main outcome was the difference in QoL scores between IG and NIG after 3 months follow-up. Results: After 3 months, the number of patients with asthma in the IG and in the NIG was 173 and 96, respectively. QoL mean scores in the IG patients were significantly higher than those in their NIG counterparts (1.79±1.01 vs. 1.06±0.93, respectively, p<0.001). Pharmacist-based interventions overall QoL scores (multivariate-adjusted regression coefficient =0.362; p<0.001). Conclusions: Clinical pharmacist-led counseling can improve asthmatic patients’ QoL.
Still walking on the wild side? Management actions as steps towards 'semi-domestication' of hunted ungulates

Summary 1. Domestication is a process involving adaptations to man and the man-made environment. Semidomestic animals are those for which humans have only partial control over breeding, mortality, space use and food supply, and that have not been greatly modified by artificial selection. They therefore appear more similar to their wild counterparts. 2. The degree of domestication depends on the level of (i) human control over breeding, mortality, food supply, space use and thereby selection pressures; (ii) how much these differ from original states; and (iii) how strongly the phenotypic traits have been affected. 3. Synthesis and applications. Both natural and sexual selection in man-made environments may differ, and some management actions move traits of hunted ungulates closer to those associated with a semi-domestic stage; depending on the harvest pressure and selectivity, fencing, artificial feeding and predator control. There is a trade-off between high productivity of hunted ungulate populations and retaining wild traits.
Evaluation of azadirachta indica leave extract on hematology and biochemical profiles, organs weight and growth parameters of broiler chickens

We evaluate the Effect that neem leaf extract on growth, haematology and biochemical profiles and organs weight of broiler chickens to justify its inclusion in the diet of growing broiler chickens. 120 day old chicks divided into four treatment groups T1, T2, T3 and T4 of thirty (30) birds each were administered clean drinking water with 0g, 3g, 4g and 5g neem extract respectively. Impacts of neem extract treatments on growth indices suggested that Neem extract favored growth with final body weight range of 2447 and 2620g. Organ weights showed no deviation from standard values for healthy broiler birds. Hematology and serum biochemistry values were in conformity with standards for healthy broiler birds. Birds on 3g of Neem extract in their drinking water out performed birds in other treatments in assessed growth rate indices. We therefore conclude that 3g of Neem extract in their drinking water growing broiler birds encourages healthy growth and may serve as supplements for antibiotics, especially when birds are raised in areas with minimal access to veterinary service.
AN ASSESSMENT OF PRICE ACCELERATING IN IRAN USING FRANKEL PRICE MODEL AND ARDL METHODOLOGY

As reaching to economic growth, development and stability in any economy needs and assessment and determination of such important factors as inflation, occupation and production, hence relation between inflation and effective factors on prices’ level can play an important role in economy. This paper surveys short term and long term effects of effective variables on inflation and evaluates possibility of commodities price accelerating in Iran. Keywords: Accelerator, Error correction model, Inflation rate, Liquidity.
Actinomyces Ruminicola G10 - The Rumen Bacterium Recovered from Glycerol Enriched Cultivation Media

Abstract Gradual increasing of glycerol concentration up to 10% using sheep ruminal fluid as an inoculum for in vitro cultivation was accompanied by significant changes in bacterial population as documented by DGGE analysis. The resulting bacterial consortium was composed of three dominant bacteria with Actinomyces related bacterium to be predominant. Upon cultivation on media with glycerol as a sole carbon source a single bacterium was cultivated from this consortium. Isolate G10 was found to be anaerobic, Gram-positive rod-shaped bacterium. Phylogenetic analysis based on 16S rRNA gene sequences showed that G10 isolate is related to the Actinomyces ruminicola species (97.7% of similarity). The role of rumen actinobacteria is largely unknown and their participation in glycerol utilization (tolerance) has not been described yet. The G10 bacterium and related consortium could be possibly used to improve glycerol tolerance and uptake by ruminants
The “Taste of Life” as a Mechanism of Overcoming Corruption

Abstract The issue of measuring the “taste of life” is one of the main tasks in the process of management decentralization in the state. The term “taste of life” is considered to be the degree of an individual’s satisfaction from living, functioning and carrying out his own activity in society in accordance with economic rules and orders. To solve this problem, three approaches were applied by considering the “taste of life” as a function of state authorities’ services, shadow activity and communal budget. Based on mathematical modelling and the results of expert surveys in 50 communities in the Ukrainian environment, authors made an attempt to identify the degree of state’s regularities in society and to test the constructed models. According to the results, a higher “taste” on the basis of state services caused a decrease in the likelihood of a person returning after the possibility of working and living abroad. The higher “taste” caused the smaller sensitivity to institutes of the shadow economy. At the same time, the “taste” on the basis of shadow services correlates negatively with sensitivity to the state’s official engagement in business and penalties for informal activity. So, the higher this segment, the smaller the sensitivity. The behavior of those who consider communal services and the work of the community as a basic variable is quite different. The “taste” on the basis of community services cannot explain the sensitivity to the shadow institutes and dynamics of emigration. Consequently, decentralization is a way of overcoming corruption.
The Differences in Egg Quality of White Leghorn and Naked Neck Chicken

Evaluation of egg quality characteristics and influencing factors are very important to note. One of the factors that affect the quality of the egg is the breed of chicken. The research objective was to compare some parameters of egg quality between White Leghorn (WL) and Naked Neck chicken. Number of eggs collected were 49 eggs from WL and 59 eggs from Naked Neck. All variable egg quality was measured using an egg multi tester EMT-5200. For egg white grading, it was used the standards of the USDA (grade AA, A, and B). The average of egg weight was significantly (P<0.05) influenced by the breeds. Thickness of eggshell were significantly different (P<0.05) between WL and Naked Neck chicken (0.46±0.05 vs 0.43±0.04 mm). Haugh units (HU) were significantly higher in WL (67.64±9.97) compared with Naked Neck chicken (57.62±11.69). The percentage of the characteristics of the egg white on a WL chicken more on grade A (47.68%) while the Naked Neck chicken on grade B (59.18%). More yolk color WL chicken on score 4 (52.54%) and Naked Neck chicken on score 5 (48.98%). It can be concluded that, egg weight, eggshell thickness, HU, and the percentage of egg white on WL chicken showed superior than Naked Neck chicken.
Sustainable Consumption and Production: A Crucial Goal for Sustainable Development—Reflections on the Spanish SDG Implementation Report

The United Nations’ Sustainable Development Goals (SDGs) have elicited multiple initiatives worldwide, aspiring to transform the world while leaving no one behind. As reports show, some advances have been made, although these are not sufficient to counter the challenges of global environmental, socio-economic and humanitarian crises. Transitioning toward sustainable development requires simultaneous progress in all 17 SDGs. These goals represent a comprehensive framework made up of interconnected, indivisible aspects, revealing the multidimensional nature of the task. This article focuses on SDG 12, the goal that aims to ensure sustainable consumption and production. Tackling the current patterns of consumption and production is crucial for sustainability because these are the main drivers of serious environmental and social impacts. Taking the European Union’s conceptualisation of the circular economy as a reference, the article makes inroads into the transformation required to achieve this goal and interlinks it to the other 16 SDGs. Drawing on the Spanish Voluntary Report presented in 2018, the study shows the limitations in assessing progress with the tools available. Though we cannot generalise, the example of Spain provides insights of global interest. Achieving SDG 12 involves major transformations, including industrial processes and society as a whole. Evidently, this represents a huge challenge, as well as a great opportunity to foster sustainable development for policy-makers and stakeholders. Advancing towards this societal aspiration requires greater commitment in order to embrace change in a systemic and coherent way, enhancing the means of implementation and engaging all stakeholders.
Deficits in the Brain Growth in Rats Induced by Methylmercury Treatment during the Brain Growth Spurt

This paper describes the deficits in brain regional growth of rats treated with methylmercury (MeHg) among the postnatal developing phases. Rats were orally administered 10 mg/kg/day of methylmercury chloride (MMC) for 10 consecutive days from postnatal days 1 (PD-1), -14 and -35, which corresponded to the early-, late- and post-brain growth spurt, respectively. Weight-matched control rats were periodically isolated from their mother or diet and placed in an incubator for intervals of 4 to 10 hr in order to adjust the body weight to MMC-treated rats. The earlier the postnatal phase the higher the resistance to body weight loss induced by MMC. The rats were dissected on the day after final MMC treatment and the weight of organs and their mercury (Hg) concentrations were measured. Hg accumulation in the brain on the day after final treatment with 10 mg/kg/day of MMC was highest in the rats treated during the late-brain growth spurt. On the other hand, Hg accumulations in the liver and kidney increased rapidly with development of postnatal phases. Then, the brain/kidney and brain/liver ratio of Hg concentration were much higher in early postnatal rats than in later one. The weight of brain regions in MMC-treated rats was compared with those in weight-matched control rats. The significantly lower weight of the cerebrum, cerebellum and midbrain + diencephalon were confirmed in rats treated with MMC during the early-brain growth spurt. The significantly lower cerebellum weight was confirmed in rats treated with MMC during the late-brain growth spurt. The Significant differences were not observed in the brain regions in rats treated during post-brain growth spurt. In the case of human, a similar reduction of the brain weight occurred in the fetal and non-fetal infantile Minamata disease patients. The experiment using postnatal rats succeeded to reproduce the deficit in the brain growth during the early- and late brain growth spurt by MMC treatment.
Long-term monitoring of primary production in coastal waters by an improved natural fluorescence method

In order to apply the natural fluorescence method for the long-term monitoring of chl a and primary production, the seasonal variation in the light absorption coefficient of phytoplankton (a* ph ), maximum quantum yield ratio of photosynthesis to fluorescence [(Φ c /Φ f ) max ], and its light saturation index (k cf ) were examined. The mooring of a natural fluorescence sensor was conducted during winter to early spring (January to April 1998), late spring (May 2000) and summer (July to August 2000) at a station in Otsuchi Bay on the north east coast of Japan. The bio-optical parameters, a* ph , (Φ c /Φ f ) max and k cf , were measured by water sampling and incubation experiments twice a week. The temporal variation in a* ph was expressed as an exponential of chl a. This relationship varied seasonally. The variations in (Φ c /Φ f ) max were related to chl a during winter to early spring, and to chl a and temperature during late spring and summer. The value of k cf was relatively low and stable during the winter and early spring; it reached higher values during late spring to summer, when temperature and light intensities were also higher. Based on these relationships, the long-term monitoring of chl a and primary production from natural fluorescence was realized in coastal water where environmental conditions and phytoplankton abundance fluctuated markedly. By developing algorithms in various areas and seasons, as the present study has shown, the natural fluorescence method is expected to be useful for continuous monitoring of primary production, with a high spatial resolution by a mooring web of sensors, even in coastal waters.
Pursuit Beyond Competitiveness and Competitive Advantage

In the post-industrial revolution era, the competitiveness paradigm appears to have reached its limits. In this article, the authors discuss the ineffectiveness of the paradigm and propose an approach beyond competition. Their premise is that every individual searches for something everlasting and wants to leave something behind that survives. To support this, they recommend that companies revive and imbibe pre-industrial society value systems that allowed the free expression of ‘the divinery instincts’ in individuals in the form of arts and crafts while maintaining focus and coordination through the use of information technology. They propose a 3Em's path to sustaining corporate performance, viz. Embarkation, Emulation, and Emancipation. They propose that companies should quickly get over the first two phases and get on to the emancipation phase where they concentrate on setting their own standards rather than frittering away their u energy in outsmarting competition.
LEAF EPIDERMAL ANATOMY OF AREAS IN GOMBE STATE, NIGERIA

Leaf epidermal microscopy of Ipomoea carnea Jacq was studied to investigate the structure stomata and epidermal features which may be used for delimitation of the specie. Fresh leaves of Ipomoea carnea were obtained from five different LGA,S (Gombe, Y/deba, Balanga, Funakaye and Dukku ) in Gombe State, Nigeria. The specimens were stu the Stomatal features, Epidermal cell shapes and Anticlinal cell of amphistomatic leaves; one type of Stomatal complex type namely Cyclocytic. Accession 1 had the highest Stomatal Density (40.00 ± 1.00mm the Abaxial leaf surfaces while Accession 2 possessed lowest Stomatal density (23.40±7.67mm with highest Stomatal Size (88.68±1.95mm wall patterns with polygonal epidermal cell shapes were also observed. It was concluded that the presence of Cylocytic type of stomata, with large stomatal sizes greatly helped in the delimitation of the plant and could also be used for classificatio features such as trichomes could also be used for adaptation purposes.
NOTES ON ITERATIVE CLOSEST POINT ALGORITHM

Point clouds are commonly used in many areas of technical practice. Nowadays, the common applications are in area of autonomous cars and 3D terrain or object modelling. During the scanning process, the scanning device or object is moving. So, the problem of precise point cloud registration arises. In this article, we describe Iterative Closest Point (ICP) algorithm that is suitable for fine registration. We introduce some of the improvements that leads to higher precision, speed computation and efficiency. We also tested the ICP algorithm on the noisy point clouds to process the registration.
Jurnal Teknologi A Review of Snake Models in Medical MR Image Segmentation

Developing an efficient algorithm for automated Magnetic Resonance Imaging (MRI) segmentation to characterize tumor abnormalities in an accurate and reproducible manner is ever demanding. This paper presents an overview of the recent development and challenges of the energy minimizing active contour segmentation model called snake for the MRI. This model is successfully used in contour detection for object recognition, computer vision and graphics as well as biomedical image processing including X-ray, MRI and Ultrasound images. Snakes being deformable well-defined curves in the image domain can move under the influence of internal forces and external forces are subsequently derived from the image data. We underscore a critical appraisal of the current status of semi-automated and automated methods for the segmentation of MR images with important issues and terminologies. Advantages and disadvantages of various segmentation methods with salient features and their relevancies are also cited.