Miracle-dz/UniFAR-FTUs huggingface dataset:
Clavibacter michiganensis subsp. michiganensis strains from central Chile exhibit low genetic diversity and sequence types match strains in other parts of the world

Bacterial canker caused by Clavibacter michiganensis subsp. michiganensis (Cmm) is one of the most important bacterial diseases of tomato. In order to understand the emergence and dissemination of this pathogen in Chile, Chilean Cmm strains isolated from different sites in central Chile were characterized and compared to a worldwide collection of strains. Multilocus sequence analysis and typing (MLSA‐MLST) based on five housekeeping genes, i.e. atpD, dnaK, gyrB, ppk and recA, and multilocus variable number of tandem repeats (VNTR) analysis (MLVA) based on eight VNTRs were used. Low diversity was found using MLSA‐MLST among the 25 Chilean strains, which clustered into three groups, each corresponding to a single sequence type (ST). Group I contained most strains (21/25), isolated over different years from Valparaiso and O'Higgins regions. Group II contained only one strain from Maule region that was isolated in 2005. These two groups belonged to the same genetic lineage. Group III contained three strains from Valparaiso region isolated in 2004, 2012 and 2013. MLVA also distributed the strains into the same three groups. Group III strains shared the same ST as strains from Algeria, Belgium, France, the Netherlands, Uruguay and the USA. Group II strains shared the same ST as strains from Brazil and Uruguay, while Group I strains shared the same ST as two strains of unknown origin. This study shows that Cmm strains from central Chile tend to be clonal and have similar genetic profiles to strains from other countries.
Anti-money laundering systems: a systematic literature review

Purpose This paper aims to understand and document the state of the art in the anti-money laundering (AML) systems literature. Design/methodology/approach A systematic literature review (SLR) is performed using the Saudi Digital Library. The outputs published as conference proceedings, workshop proceedings, journal articles and books were all considered. The final sample size after omitting out-of-scope selections was 27 documents, which mainly span from 2015 to 2020. Findings The sample is discussed based on a categorization, which demarcates solutions, machine learning, data sources, evaluation methods, implementation tools, sampling techniques and regions of study. Originality/value This SLR could serve as a useful basis for researchers and salient decision-makers, who are seeking to understand the nature and extent of the currently available research into AML systems.
Mechanisms of Action of Multipotent Mesenchymal Stromal Cells in Tendon Disease

Multipotent mesenchymal stromal cells (MSCs) are a promising therapeutic tool to treat tendon disease. Aiming to establish successful treatment approaches and to fully exploit the regenerative potential of the MSC, it is crucial to understand their mechanisms of action. However, these can be multifaceted and strongly context-sen-sitive and are still not well-understood in the context of tendon disease. This review aims to shed light on the different possible mechanisms, including engraftment, tenogenic differentiation, extracellular matrix synthesis and remodeling, immunomodulation, pro-angiogenetic effects, trophic support, and protection of resident tendon cells. Evidence from experimental and clinical (veterinary) case studies was compiled and interpreted in conjunction with the respective in vitro and animal models used.
Regeneration possibilities of the skeletal muscle cell around a titan implant

B. A. BUMBU , V. RUS , F. RUXANDA , A. BUMBU , I. OSWALD (3) 1 Department of Dental Medicine, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania 2 Departments of Cell Biology Histology and Embryology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania 3 Department of Preclinical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania *Corresponding author Vasile Rus, Ph.D. Departments of Cell Biology Histology and Embryology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, 3-5, Calea Manastur Street, Cluj-Napoca 400372, Romania Phone: +40(0)264.596. 384/192, Fax: +40(0)264.593. 792, e-mail: vasilerus2002@yahoo.com
Root rot grain crops on Cereals caused by the phytopathogenic fungi

Researching the special and infraspecial structure in causative agent populations of the most dangerous diseases root rots of cereals in various regions of the Russjan Federation has been carried out. The defeat of cereals root rots old in Russia causes in the a complex patogenic. More often meet Fusarium culmorum (W.G.Sm.) Sacc. , F. oxysporum (Schlecht.) Snyd.et Hans. , F. heterosporum Nees. , F. sporotrichiella nom.nov. Bilai F. gibbosum App.et Wr.emend Bilai. , F. avenaceum (Fr.) Sacc. and Bipolaris sorokiniana (Sacc.) Shoem. , Alternaria spp.
El coronavirus expone brutalmente las falacias de la economía neoclásica y la globalización

This article argues that the coronavirus is the result of excessive human pressure on the biosphere, and that the effects of the pandemic it has caused in the world have been aggravated by policy recommendations derived from conventional economic thought, whose advocates - to keep their paradigm safe - will argue, just as in the 2008 financial crisis, that the current health crisis was not predictable (English) [ABSTRACT FROM AUTHOR] En este articulo se argumenta que el coronavirus es el resultado de la excesiva presion humana sobre la biosfera, y que los efectos de la pandemia que ha causado en el mundo han sido agravados por las recomendaciones de politica derivadas del pensamiento economico convencional, cuyos defensores -para mantener a salvo su paradigma- argumentaran, igual que en la crisis financiera de 2008, que la actual crisis sanitaria no era predecible (German) [ABSTRACT FROM AUTHOR] Este artigo argumenta que o coronavirus e o resultado de pressao humana excessiva na biosfera e que os efeitos da pandemia que causou no mundo foram agravados por recomendacoes de politicas derivadas do pensamento economico convencional, cujos advogados - Para manter seu paradigma seguro - eles argumentarao, assim como na crise financeira de 2008, que a atual crise da saude nao era previsivel (Portuguese) [ABSTRACT FROM AUTHOR] Copyright of Revista de Economia Institucional is the property of Universidad Externado de Colombia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )
Controle de quadricóptero via linearização por realimentação robusta associada à síntese H

O presente trabalho trata do projeto de uma lei de controle para o modelo nao linear de um quadricoptero sujeito a incertezas parametricas. O sistema de controle e projetado por meio da combinacao de tecnicas de linearizacao por realimentacao com a sintese H∞. Os resultados das simulacoes numericas indicamque a associacao de uma lei de linearizacao por realimentacao a um controlador robusto e eficiente para a regulacao de sistemas dinâmicos nao lineares, operando longe do ponto de equilibrio. Tambem e observado que, para uma certa classe de sistemas nao lineares, existe equivalencia entre as tecnicas de linearizacao porrealimentacao consideradas.
Report 23: State-level tracking of COVID-19 in the United States

H Juliette T Unwin∗, Swapnil Mishra2,∗, Valerie C Bradley∗, Axel Gandy∗, Michaela A C Vollmer, Thomas Mellan, Helen Cou-pland, Kylie Ainslie, Charlie Whittaker, Jonathan Ish-Horowicz, Sarah Filippi, Xiaoyue Xi, Melodie Monod, Oliver Ratmann, Michael Hutchinson, Fabian Valka, Harrison Zhu, Iwona Hawryluk, Philip Milton, Marc Baguelin, Adhiratha Boonyasiri, Nick Brazeau, Lorenzo Cattarino, Giovanni Charles, Laura V Cooper, Zulma Cucunuba, Gina CuomoDannenburg, Bimandra Djaafara, Ilaria Dorigatti, Oliver J Eales, Jeff Eaton, Sabine van Elsland, Richard FitzJohn, Katy Gaythorpe, William Green, Timothy Hallett, Wes Hinsley, Natsuko Imai, Ben Jeffrey, Edward Knock, Daniel Laydon, John Lees, Gemma Nedjati-Gilani, Pierre Nouvellet, Lucy Okell, Alison Ower, Kris V Parag, Igor Siveroni, Hayley A Thompson, Robert Verity, Patrick Walker, Caroline Walters, Yuanrong Wang, Oliver J Watson, Lilith Whittles, Azra Ghani, Neil M Ferguson, Steven Riley, Christl A. Donnelly, Samir Bhatt1,∗ and Seth Flaxman∗
Antibiotics inhibiting bacterial protein synthesis, and novel resistance mechanisms

The ribosome and protein synthesis are major targets within the cell for inhibition by antibiotics, such as the tetracyclines. The tetracycline family of antibiotics represent a large and diverse group of compounds, ranging from the naturally produced chlortetracycline, introduced into medical usage in the 1940s, to second and third generation semi-synthetic derivatives of tetracycline, such as doxycycline, minocycline and more recently the glycylcycline tigecycline. Here we describe the mode of interaction of tetracyclines with the ribosome and mechanism of action of this class of antibiotics to inhibit translation. Additionally, we provide an overview of the diverse mechanisms by which bacteria obtain resistance to tetracyclines, ranging from efflux, drug modification, target mutation and the employment of specialized ribosome protection proteins.
Acute Pancreatitis due to Phytobezoar Case Report and Mini-Review of Literature

The term “bezoar” defines undigested food particles accumulation anywhere in the gastrointestinal tract. Clinical findings vary according to the localization of bezoar in the gastrointestinal tract. Acute pancreatitis induced by duodenal bezoar is a rare condition. In this article, we present a case of phytobezoar that obstructed the duodenum and presented with acute pancreatitis clinic with the mini-review of the literature
Age‐dependent habitat relationships of a burned forest specialist emphasise the role of pyrodiversity in fire management

1. Variation in fire characteristics, termed pyrodiversity, plays an important role in structuring post-fire communities, but little is known about the importance of py rodiversity for individual species. The availability of diverse post-fire habitats may be key for fire-associated species if they require different resources at different life-history stages. 2. We tested for age-specific habitat relationships in the black-backed woodpecker, a post-fire specialist. We used radio-telemetry to track fledgling and adult wood peckers in burned forests and built resource selection functions to compare the effect of stand-, tree- and snag-level covariates between adults and fledglings. 3. Fledgling black-backed woodpeckers selected habitat with more live trees than adults and used more heterogeneous habitats burned at lower severity, illustrat ing strong age-dependent effects on habitat selection. Within selected stands, fledglings were less likely to use snags and more likely to use live trees when com pared to adults, but both age classes showed strong positive selection for larger-diameter trees (live and dead). Over
Rub-tree selection by Andean bears in the Peruvian dry forest

Abstract To advance our knowledge on the rubbing behavior of Andean bears (Tremarctos ornatus), we assessed characteristics of their rub-trees in the Peruvian tropical dry forest, where water is a rare and critical resource. We registered characteristics of rubbed and unrubbed trees and shrubs along bear trails in an area of approximately 100 km2 surrounding 7 waterholes in the western Andes foothills of Peru during austral summer 2014–2015. Analysis of 94 trees selected for rubbing (hereafter, rub-trees) and 253 available unmarked trees within a 5-m radius of each rub-tree showed that bears selected trees to rub that were relatively small and close to waterholes. Bears seemed to avoid the most common tree species, palo santo (Bursera graveolens), for tree-rubbing. We suggest that waterholes are important habitat features for Andean bears in the Peruvian dry forest, and that these sites be incorporated into conservation and land use management.
Endoglycan plays a role in axon guidance and neuronal migration by negatively regulating cell-cell adhesion

Cell migration and axon guidance are important steps in the formation of neural circuits. Both steps depend on the interactions between cell surface receptors and molecules on cells along the pathway. In addition to cell-cell adhesion, these molecular interactions provide guidance information. The fine-tuning of cell-cell adhesion is as an important aspect of cell migration, axon guidance, and synapse formation. Here, we show that Endoglycan, a sialomucin, plays a role in axon guidance and cell migration in the central nervous system. In the absence of Endoglycan, commissural axons failed to cross the midline of the spinal cord. In the developing cerebellum, a lack of Endoglycan prevented migration of Purkinje cells and resulted in a stunted growth of the cerebellar lobes. Taken together, these results support the hypothesis that Endoglycan acts as a negative regulator of cell-cell adhesion in both commissural axon guidance and Purkinje cell migration.
Einfluss eines durch züchterische Maßnahmen veränderten Milchfett/Milcheiweiß-Verhältnisses auf Treibhausgas-Emissionen in der Milcherzeugung

Die Notwendigkeit der Reduzierung der Emissionen von Treibhausgasen ist von weltweiter Bedeutung. Die weitere genetisch-zuchterische Erhohung des Milcheiweis-gehaltes – bei gleichzeitiger Absenkung des Milchfettgehaltes – auf hohem Leistungsniveau (z.B. 9000 kg Milch je Kuh und Jahr) fuhrt zu einem reduzierten Energieaufwand (fur die Milchfetterzeugung) und einem erhohten Futterproteinbedarf (fur die Milcheiweiserzeugung) des Einzeltieres. Dies beeinflusst – bei konstant hohem Leistungsniveau – die Ausscheidungen (z.B. N-Anfall, CH4-Emission) des Einzeltieres insgesamt nur relativ gering. Bezogen auf das produzierte Milcheiweis wird der Aufwand jedoch geringer und der positive Effekt auf die Umwelt deutlicher. Unter Berucksichti-gung der berechneten Methan- bzw. auch N-Ausscheidungen sollte ein hohes Niveau tierischer Leistungen (unter gezielter Beachtung eines hohen Milcheiweisgehaltes) und eine dadurch mogliche Reduzierung der Zahl erforderlicher Milchkuhe die (gegenwartig) effektivste Masnahme sein, eine verminderte Methanemission zu erzielen.
Feminist futures: #MeToo’s possibilities as poiesis, techné, and pharmakon

ABSTRACT In this article we argue that the #MeToo movement contributes tocombatting sexual harassment by acting as techné (tools), which offer a range of poietic (world making) possibilities given the contexts under which #MeToocirculates. We situate #MeToo as pharmakon (creation and constraint)to highlight how the movement enables new feminist possibilities for action and simultaneously restricts the movement’s limits. Drawing on existing coverage of #MeToo featured in popular media stories, we consider the layers of meaning and circulation of some key #MeToo tweets and their framings within media accounts of the movement. We focus on tweets that emphasize remembering experiences of misogyny, assault, and harassment, in addition to implicating social structures in perpetuating rape culture. In employing poiesis and pharmakon as orienting frames, we acknowledge both the discursive power a movement like #MeToo holds and the forms of occlusion, privilege, and marginalization that emerge.
Gamification for Sales Incentives

Gamification as a use of game mechanisms for motivation in non game contexts has an increase popularity and is priced as a hottest subject in management. However there are few research on gamification in compensation systems, specially for sales-force. The article discussed some problems of compensation systems for different types of sales representatives, as well as limitation of agency theory as a theoretical basis for creation of adequate incentive systems in contemporary sales function of organization. The results of questionnaire study based on opinion of 100 sales representatives from technological companies about psychological (level of risk acceptance) and contextual factors (long sales-cycle and low need for income) that facilitate acceptance of draw based incentive systems for group and individual bonus are described.
Analysis of Attribute Reduction Effectiveness on The Naive Bayes Classifier Method

Naïve Bayes is a prediction method that contains a simple probabilistic based on the application of the Bayes theorem (Bayes rule) with the assumption that the dependence is substantial. Classification is a technique in data mining to form a model from a predetermined data set. Data mining techniques are the choices that can overcome in solving this problem. Therefore, researchers make a comparison of Naïve Bayes by modifying using PCA. Improving the comparative performance of the Naive Bayes method by weighting using Principal Component Analysis (PCA) and Naive Bayes was carried out in this study. Research conducted on the classification model of Naïve Bayes (PCA + Naïve Bayes) using the Iris dataset that simplified into two attributes, four classes and 147 instances with an accuracy rate of 97.78% with a classification error rate of 2.22%. Meanwhile, the Conventional Naïve Bayes classification model uses four attributes with four classes from the Iris dataset, which has an accuracy rate of 95.45% with a classification error rate of 4.55%. Based on the test results of the classification model, it can be concluded that the success of the PCA can be used as a reference to improve the accuracy performance of the Naïve Bayes classification model.
An Immune Chaotic Niche Genetic Algorithm for Monitoring Distribution Problem in Self-Organizing Wireless Sensor Network

Due to the sensors are restricted in sensing capabilities, monitoring distribution has become a challenging problem in self-organizing wireless sensor network (SOWSN). Micro nodes are self-organized tiny devices with limited sensing capabilities. Careful monitoring distribution scheme can be a suitable optimizing means for achieving the required high target detection rate goals, comprising sensing capacity restrictions. However, the monitoring distribution problem is a typical NP-hard combinatorial stochastic optimization problem. In this study, an immune chaotic niche genetic algorithm (ICNGA) to enhance the target detection rate is explored. Advanced operators such as immune operator and chaotic operator are also incorporated into the ICNGA to increase the explore capacity. The represented immune selection and chaotic generation depending on ICNGA with global search capability can simultaneously optimize multiple variables. Simulation results identify that the proposed algorithm can get a higher target detection rate over SFLA and SA. Besides that, the convergence speed of the presented ICNGA is much higher than that of SFLA and SA. So the proposed method significantly enhanced the efficiency.
Multilayer network analysis of miRNA and protein expression profiles in breast cancer patients

MiRNAs and proteins play important roles in different stages of tumor development and serve as biomarkers for the early diagnosis of cancer. A new algorithm that combines machine learning algorithms and multilayer complex network analysis is hereby proposed to explore the potential diagnostic values of miRNAs and proteins. XGBoost and random forest algorithms were employed to exclude unrelated miRNAs and proteins, and the most significant candidates were retained for the further analysis. Given these candidates’ possible functional relationships to one other, a multilayer complex network was constructed to identify miRNAs and proteins that could serve as biomarkers for breast cancer. Proteins and miRNAs that are nodes in the network were subsequently categorized into two network layers considering their distinct functions. Maximal information coefficient (MIC) was applied to assess intralayer and interlayer connection. The betweenness centrality was used as the first measurement of the importance of the nodes within each single layer. To further characterize the interlayer interaction between miRNAs and proteins, the degree of the nodes was chosen as the second measurement to map their signalling pathways. By combining these two measurements into one score and comparing the difference of the same candidate between normal tissue and cancer tissue, this novel multilayer network analysis could be applied to successfully identify molecules associated with breast cancer.
Thermoelectric power in misfit cobalties ceramics: optimization by chemical substitutions

The ceramics of misfit cobaltites form a large family of layer oxides which exhibit large values of Seebeck coefficient (S 300K ≥ 90μV.K -1 ). They can be divided in two categories depending on the number of the rocksalt-type (RS) layers, n = 3 or n = 4, separating the [CoO 2 ] conducting layers. From the comparison of their structural features, it is found that the S values are governed by the incommensurability ratio and/or the charge of the RS block. This is clearly evidenced by making chemical substitutions at the level of the RS block: isovalent but with cations of different ionic radius (r Ba 2+ > r Sr 2+ > r Ca 2+ ) modifying the incommensurability ratio or aliovalent substitutions for cobalt (Pb 4+ , Ti 4+ ) which keep unchanged the structural incommensurability but make the RS charge changing.
Regulation of Neuronal Excitability by the RNA-Binding Protein Rbfox1

Author(s): Vuong, Celine Kim | Advisor(s): Black, Douglas L | Abstract: Dysfunction of the neuronal RNA binding protein RBFOX1 has been linked to epilepsy and autism spectrum disorders. Rbfox1 loss in mice leads to neuronal hyperexcitability and seizures, but the physiological basis for this is unknown. We identify the vSNARE protein Vamp1 as a major Rbfox1 target using high throughput RNA-seq and CLIP-seq in adult mouse brain. Vamp1 is strongly downregulated in Rbfox1 Nes-cKO mice due to loss of 3’ UTR binding byRbfox1. Using viral induction by AAVs and reporter assays in primary cultured neurons, we show that cytoplasmic Rbfox1 stimulates Vamp1 expression in part by blocking microRNA-9. We find that Vamp1 is specifically expressed in inhibitory neurons in vivo and in cultured neurons using immunofluorescence. Electrophysiological analyses in acute hippocampal slices show that both Vamp1 knockdown and Rbfox1 loss lead to decreased inhibitory synaptic transmission and E/I imbalance. To assay whether the inhibitory defects in the Rbfox1 cKO are due to Vamp1 loss, we then use stereotaxic injection of AAVs to re- express Vamp1 selectively within Rbfox1 cKO interneurons. Remarkably, re-expression of Vamp1 rescues the electrophysiological changes in the Rbfox1 cKO, indicating that Vamp1 loss is a major contributor to the Rbfox1 Nes-cKO phenotype. The regulation of interneuron-specific Vamp1 by Rbfox1 provides a paradigm for broadly expressed RNA- binding proteins performing specialized functions in defined neuronal subtypes.