Miracle-dz/UniFAR-FTUs huggingface dataset:
A copa em tweets: análise comparativa do uso das hashtags #EstadaonaCopa e #BairristanaCopa

Neste trabalho, procuramos analisar e comparar a utilizacao de hashtags de cobertura no Twitter por um site jornalistico e outro humoristico durante a Copa do Mundo de 2014: o jornal O Estado de S. Paulo, que utilizou a hashtag #EstadaonaCopa para sua cobertura em sites de rede social, e o site satirico O Bairrista, que adotou a hashtag #BairristanaCopa. O estudo foi operacionalizado a partir da combinacao de observacao com analise de redes sociais como metodos para compreender a estrutura e a dinâmica das redes em torno das respectivas hashtags. Resultados apontam para estruturas de rede semelhantes, porem com dinâmicas diferentes observadas em cada um dos casos estudados.
Two Closely Related Strains Associated With Pertussis Resurgence in Israel

Eighty-two isolates of Bordetella pertussis analyzed by pulsed-field gel electrophoresis from the epidemic years, 2007 to 2008, revealed 4 strains with 2 closely related isolates accounting for 95% of the circulating strains. The most common Israeli strain has the same pulsed-field gel electrophoresis cluster as the dominant European BpSR11 strain (pulsed-field gel electrophoresis cluster IV&bgr;) identified in the 1999 to 2004 EU Pertstrain II project.
Antibacterial Characterization of Silver Nanoparticles against E. Coli ATCC-15224

吝啬的尺寸的银 nanoparticles 16 nm 被惰性的气体综合冷凝作用(IGC ) 方法。 晶体结构，形态学和 nanoparticles 尺寸评价被 X 光检查衍射(XRD ) 和传播电子显微镜学(TEM ) 进行。 对克否定的细菌 Escherichia 关口 i (E.coli ) 的粒子集中的功能象稳固的生长媒介一样在液体被执行的这些银 nanoparticles 的抗菌剂活动。 扫描电子显微镜学(SEM ) 和 TEM 研究证明在和 E.coli 的相互作用以后的银 nanoparticles 遵守了并且渗透进细菌的房间。 银 nanoparticles 的抗菌剂性质被归因于他们的 tptalsurface 区域，当到 nanoparticles 的体积比率的更大的表面为提高的抗菌剂活动提供更有效的工具。
TCAM-based flow lookup design on FPGA and its applications

TCAM is now emulated using FPGAs and based on memory known as RAM or register. Most of them are made just using register- or RAM-based resource individually when mapped to FPGA hardware. This paper presents a 4×4 flexible Basic-TCAM architecture that can be flexibly designed based selectively on memory-based or register-based FPGA resource or both of them in combined manner. In addition, it can also allow a scalable architecture. A wider and deeper TCAM of size 512×36 built based on it seizes only 73,728 bits and 1,503 logic utilization and supports competitive search latency of 1 clock cycle over Altera Cyclone V FPGA. A typical flow lookup design based on this Basic-TCAM architecture uses a TCAM of size 4×16 and a simple parser to do a flow lookup. This design application is then taken place in a simple VLAN-based switch system for further feasible application of the TCAM in this work.
The Impact of Lipid on Contact Angle Wettability

Purpose. To analyze the effect of in vitro lipid doping on conventional hydrogel (CH) and silicone hydrogel (SH) lens wettability, assessed by sessile drop contact angle (CA) measurement. Methods. Nine contact lens materials, five SHs and four CH, were incubated with two different lipid tear solutions (LTS) containing cholesterol, cholesteryl oleate, oleic acid, oleic acid methyl ester, and triolein. The first LTS was a “low” concentration solution, which was close to human values, and the second was a “high” concentration. Lenses were soaked in the two LTS types for 2 or 5 days and compared with lenses soaked in phosphate buffered saline (PBS) only. After soaking, advancing CAs were measured on a customized computerized device using a sessile drop method. Results. Compared with PBS, CAs for untreated SHs were unaffected by soaking in the LTS, with typical CA values of >95° (p > 0.05). The surface-treated SH materials exhibited markedly reduced CAs after lipid exposure, with the high concentration LTS reducing the CA to <5° (p < 0.01). The CH materials all exhibited lower CAs after soaking, with values typically decreasing to 35°, which was significantly lower than that seen with PBS (p < 0.01). Conclusion. Exposure to lipid may improve the wettability of certain SH and CH materials, particularly those SH materials that are surface treated. This may help to explain why certain SH materials appear to improve in comfort for some patients during the first few hours or days of wear.
Methane discharge from a submarine mud volcano - A multiple-method approach

Submarine methane discharge manifests in different forms and occurs on different spatial scales. Physical, biological and geochemical processes interact at the seafloor. Comprehension and description of such complex systems requires a suite of different sampling and in situ measurement technologies. As an example, investigations carried out at a submarine mud volcano are described. Multi-method investigations are challenging in respect to handling, technical inter-operability as well as synchronization and integration of the data obtained.
Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligo‐astrocytomas

The aims of this study were to correlate cytogenetic studies and molecular genetic loss of heterozygosity (LOH) analyses in human astrocytomas and mixed oligo‐astrocytomas, and to locate putative tumor suppressor genes on chromosome 10. Paired blood and tumor samples from 53 patients were analyzed. The tumors included 45 diffuse astrocytomas (39 grade 4, 4 grade 3, and 2 grade 2), 1 astroblastoma, and 7 mixed oligo‐astrocytomas (2 grade 4,4 grade 3, and 1 grade 2). By cytogenetic analyses the most common numeric chromosome abnormalities were +7, −10, −13, −14, −17, +19, −22, and −Y. The most common structural abnormalities involved chromosome arms 1p, 1q, 5p, and 9p. By LOH and dosage analysis the most common molecular genetic abnormalities were of chromosome arms 5p, 6p, 7q, 9p, 10p, 10q, 13q, 14q, 17p, and 19p. When the results of all methods were combined, the most commonly abnormal chromosomes were, in descending frequency, 10, Y, 17, 7, 13, and 9. In 80 percent of cases the cytogenetic and molecular genetic studies were concordant. LOH studies were more sensitive in detecting loss of genetic material than cytogenetic analyses and accounted for 60% of the discordant results. When there were structural abnormalities, such as translocations or inversions, cytogenetic analysis was more sensitive in detecting an abnormality than molecular genetic studies. In addition to the 24 tumors which appeared to lose an entire copy of chromosome 10, there were 10 tumors with molecular genetic or cytogenetic evidence of loss of only a portion of chromosome 10. The genetic analyses of these tumors suggest that there are 2 regions on chromosome 10 that may contain potential tumor suppressor genes. One lies distal to locus D10S22 from 10q22 to 10qter, and the other lies proximal to locus TSTI on the 10q arm near the centromere or on the 10p arm. © 1992 Wiley‐Liss, Inc.
Imaging of musculoskeletal disorders related to pregnancy.

OBJECTIVE This article provides an overview of the typical appearance of biomechanical and physiologic changes in pregnancy and an update on related pathophysiology. Conditions occurring during the childbearing, delivery and postpartum periods will be reported separately. CONCLUSION Pregnancy causes biomechanical and physiologic changes that may be responsible for a wide spectrum of musculoskeletal disorders in the mother.
A Solution of Sleep Deprivation Attack in Clustered Network

: With the modernization, Wireless Sensor Network (WSN) sensors are gaining importance in the real world. Though the sensor nodes have low power, sensors are widely used in detecting pollution, temperature, pressure and other various applications. Energy of wireless sensor nodes is not rechargeable. Energy-constrained sensor networks periodically place nodes to sleep in order to extend the network lifetime. Denial of sleep attack is a great threat to the lifetime of sensor networks as it prevents the nodes from going into sleep mode. There are various attacks which affect the energy of sensor node. Due to which network’s life shortens. In this paper sleep deprivation attack is discussed and the prevention as to increase network’s life.
Signaling Mechanisms in Mammalian Myoblast Fusion

A number of signaling pathways coordinate the development and repair of muscle fibers. Myoblast fusion is a critical process that contributes to the growth of muscle during development and to the regeneration of myofibers upon injury. Myoblasts fuse with each other as well as with multinucleated myotubes to enlarge the myofiber. Initial studies demonstrated that myoblast fusion requires extracellular calcium and changes in cell membrane topography and cytoskeletal organization. More recent studies have identified several cell-surface and intracellular proteins that mediate myoblast fusion. Furthermore, emerging evidence suggests that myoblast fusion is also regulated by the activation of specific cell-signaling pathways that lead to the expression of genes whose products are essential for the fusion process and for modulating the activity of molecules that are involved in cytoskeletal rearrangement. Here, we review the roles of the major signaling pathways in mammalian myoblast fusion. Skeletal muscles are formed by the fusion of multiple myoblasts during development. Myoblast fusion is also essential for the growth and repair of injured myofibers. Recent investigations have shown that the process of myoblast fusion involves the activation of several cell signaling pathways, including those mediated by nuclear factor κB, mitogen-activated protein kinases, Wnt, calcineurin–nuclear factor of activated T cells c2, transforming growth factor–β–Smad4, and the Rho guanosine triphosphatases. In this Review, which contains 2 figures and 84 references, we summarize the mechanisms by which the activation of these signaling pathways stimulates myoblast fusion.
Towards reliable face localization in complex images

Face detection is the first step in many face image processing applications. This paper presents a simple, fast and robust method for reliable detection of faces in real-life images. We introduce a novel technique for distinguishing different skin colors, a capability that most of the other skin color based approaches lack. By distinguishing different shades of skin we are able to accurately detect facial regions even in complex scenes with near skin color backgrounds. Once the algorithm finds a candidate skin colored region, if verifies the region for being a face using a facial template composed with stable facial features. The algorithm can reliably detect multiple near-frontal, near-upright faces at different scales even in the presence of spectacles. We test the effectiveness of the method on various standard video sequences and the Family Database made available by Hsu et al.
METABOLIC HEALTH Pancreatic b cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

INTRODUCTION: The circadian clock is a molecular oscillator that coordinates behavior and physiology in anticipation of the daily light cycle. Desynchrony of circadian cycles, through genetic or environmental perturbation, contributes to metabolic disorders such as cardiovascular disease, obesity, and type 2 diabetes. We previously showed that disruption of the clock transcription factors CLOCK and BMAL1 in the pancreas causes hypoinsulinemic diabetes in mice. The mechanism(s) linking clock dysfunction to pancreatic b cell failure and the means by which CLOCK and BMAL1 affect glucose metabolism in the whole organism are not well understood.
Evaluation of anti-inflammatory and antinociceptive activities of Murraya exotica

Context: Leaves of Murraya exotica L. (Rutaceae) are used for the treatment of various disorders such as cough, fever, and infectious wounds, as well as alleviating pains in folk medicine in southern China. Objective: The objectives of this study were to investigate the in vivo antinociceptive and anti-inflammatory activities of ethanol (70%) extracts and isolated compounds obtained from the dried leaves of M. exotica. Materials and methods: The antinociceptive activities were evaluated with the methods of acetic acid-induced writhing response and hot-plate latent pain response test. Carrageenan induced hind paw edema, xylene induced ear edema, and a rat knee osteoarthritis model were employed to measure the anti-inflammatory activities. The compounds were isolated using column chromatography and thin-layer chromatography, and the structures identified by 1H NMR, 13C NMR, MS, and IR. Results: The ethanol (70%) extracts significantly decreased in the acetic acid-induced writhing response; increased in hot-plate latency; suppressed xylene induced ear swelling and the carrageenan-induced paw edema effectively. In the rat knee osteoarthritis model, the treatment of the ethanol (70%) extracts resulted in a significant increase in the activity of superoxide dismutase, an inhibition on inducible nitric oxide synthase activity, and a decrease in the contents of interleukin-1β and tumor necrosis factor-α of the rat serum. Following this, we explored the components of the ethanol (70%) extracts and isolated six known coumarins, including murracarpin, which exhibited the most potential in antinociceptive and anti-inflammatory activities. Discussion and conclusion: M. exotica displayed remarkable antinociceptive and anti-inflammatory activities.
Mutations of the p53 gene as a prognostic factor in aggressive B-cell lymphoma.

BACKGROUND Mutations of the p53 gene are associated with a poor prognosis in several types of cancer. We investigated the prognostic importance of p53 mutations in patients with aggressive B-cell lymphoma. METHODS We examined the relation between the presence or absence of a detectable p53 mutation in lymphoma cells and the response to chemotherapy and overall survival in 102 previously untreated patients with aggressive B-cell lymphoma. Mutations of the p53 gene were identified by polymerase-chain-reaction-mediated analysis of single-strand conformation polymorphisms and by direct sequencing. RESULTS Of 102 cases of aggressive B-cell lymphoma, 22 (22 percent) involved p53 mutations. The rate of complete remission was significantly lower in patients with a tumor carrying a p53 mutation (6 of 22 patients, 27 percent) than in those with the wild-type p53 gene (61 of 80 patients, 76 percent) (P<0.001). Overall survival was significantly lower among patients with p53 mutations than among those with the wild-type p53 gene; the Kaplan-Meier estimates of survival at five years were 16 percent and 64 percent, respectively (P<0.001). Multivariate analysis incorporating prognostic factors from the international prognostic index demonstrated that p53 mutations had independent effects on the rates of complete remission and survival. When we categorized patients according to the international prognostic index, we found no effect of p53 mutations in patients in the groups at high-intermediate and high risk. However, these mutations were significantly associated (P< 0.001) with low rates of complete remission (33 percent vs. 91 percent) and survival (27 percent vs. 81 percent at five years) in the groups at low and low-intermediate risk. CONCLUSIONS Mutations of the p53 gene are associated with a poor prognosis in patients with aggressive B-cell lymphoma.
Is It Risky to Use Kidneys from CDC‐Increased Risk Donors?

The risk of transmitting infectious agents by blood and tissue to patients remains one of the great fears surrounding solid organ transplantation (2). Indeed, one commonly cited reason for organ discard is the risk of infectious disease transmission by such organs (1). Agents at risk for transmission include hepatitis C virus (HCV), hepatitis B virus (HBV), cytomegalovirus (CMV), West Nile virus, Epstein– Barr virus (EBV), and others. However, it was the recognition that human immunodeficiency virus (HIV) could be transmitted that has largely driven public policy regarding the screening of blood and tissue donors for transmissible infections. In fact, the FDA, which regulates blood and tissue donation in the United States, has taken the stance that any transmission of HIV, HCV, or HBV is unacceptable and that no amount of money is too much to protect the nation’s blood supply. While this may be true of the nation’s blood supply, the acceptable risks with life saving solid organ transplants are different (3).
A Rare Case of Pleural Effusion Burkitt ’ s Lymphoma with Tumor Lysis Syndrome in an HIV , HHV 8 , EBV , and HCV Negative Young Male Patient

We report an unusual case of a 25 year-old male with Burkitt’s like disease associated with Primary Effusion Lymphoma (PEL), who was negative for HIV, HHV8, HCV, and EBV. The pleural effusion contained lymphoma cells with B-cell lineage and c-myc gene rearrangement. The patient had a rapidly progressive and fatal course and died from tumor lysis syndrome. This is the second reported case in the literature of such unique characteristics. Further understanding of the molecular and pathogenetic mechanisms underlying this disease is warranted.
Skylight for Interior Lighting Design

It is inevitable for indoor lighting design to render a room lit by natural light, especially for an atelier or an indoor pool where there are many windows. This paper proposes a method for calculating the illuminance due to natural light, i.e. direct sunlight and skylight, passing through transparent planes such as window glass. The proposed method makes it possible to efficiently calculate such illuminance accurately, because it takes into account both non‐uniform luminous intensity distribution of skylight and the distribution of transparency of glass according to incident angles of light. Several examples including the lighting design in an indoor pool, are shown to demonstrate the usefulness of the proposed method.
The effect of matching primary representational system predicates on hypnotic relaxation.

Abstract The newly-emerging and rapidly growing neuro-linguistic programming model of communication states that conversational language reflects a favored sense for processing information, the “primary representational system,” (PRS). Using similar language structures while interacting is thought to increase rapport and influence. This study tested that assumption. Thirty subjects were exposed to three different hypnotic inductions varying in sensory language structure according to major representational systems. Subjects were evaluated by EMG for relaxation obtained from compatible and noncompatible inductions. Subjects objectively obtained greatest relaxation when experiencing hypnotic inductions containing predicates corresponding to their PRS (p < .05). Matching PRS predicates increases the relaxation level of subjects exposed to matching and nonmatching hypnotic inductions. Identifying and matching PRS language structures appears to enhance rapport and influence.
Implementation of electronic logbook for trainees of general surgery in Thailand.

BACKGROUND All trainees are required to keep a record of their surgical skill and experiences throughout the trainingperiod in a logbook format. Paper-based logbook has several limitations. Therefore, an electronic logbook was introduced to replace the paper-based logbook. MATERIAL AND METHOD An electronic logbook program was developed in November 2005. This program was designed as web-based application based upon PHP scripts beneath Apache web server and MySQL database implementation. Only simpliJfied and essential data, such as hospital number diagnosis, surgical procedure, and pathological findings, etc. are recorded. The electronic logbook databases between Academic year 2006 and 2011 were analyzed. RESULTS The annual recordedsurgical procedures gradually increasedfrom 41,214 procedures in 2006 to 66,643 procedures in 2011. Around one-third of all records were not verified by attending staffs, i.e. 27.59% (2006), 31.69% (2007), 18.06% (2008), 28.42% (2009), 30.18% (2010), and 31.41% (2011). On the Education year 2011, the three most common procedural groups included colon, rectum & anus group, appendix group, and vascular group, respectively. CONCLUSION Advantages of the electronic logbook included more efficient data access, increased ability to monitor trainees and trainers, and analysis of procedural varieties among the training institutes.
Study of Power Transfer Capability of DC Systems Incorporating AC Loads and a Parallel AC Line

Concepts of maximum power transfer of DC systems and associated AC voltage variations, particularly at inverter stations having low short-circuit ratios, have been extended to include various AC load models and an AC line in parallel with the DC line. The operating capabilities are shown to vary from those predicted from either a Thevenin AC source model or the corresponding short-circuit ratio. The study used an AC/DC load flow program.
Ventricular enlargement in MS

Objectives: To investigate ventricular enlargement (VE) over 1 year at three different stages of multiple sclerosis (MS). Methods: A semi-automated technique for measuring VE was applied to MRI scans in 26 patients with clinically isolated syndromes (CIS) suggestive of MS, 30 with early relapse-onset MS of 1 year duration, 41 with established relapsing remitting (RR) MS, and 23 with secondary progressive (SP) MS. Results: VE at 1 year was seen in early MS (median increase 0.3 mL [p = 0.003]), RRMS (median increase 0.5 mL [p = 0.001]), and SPMS (median increase 1.1 mL [p = 0.001]). Allowing for age there was more VE in the SPMS group (p = 0.005). No VE was observed in the CIS only group (median decrease −0.001 mL [p = 0.829]). Significant increases in T2 and T1 hypointense lesion load volume were seen in all MS subgroups: there were no differences between the groups in T2 volume increase but there was a larger increase in T1 hypointense lesion volume in the SPMS group compared with early RRMS. Conclusions: Ventricular enlargement is a sensitive measure of progressive cerebral atrophy that is seen at all stages of multiple sclerosis (MS) and is more marked in secondary progressive than relapsing remitting MS.
Residual force enhancement in skeletal muscle

Residual force enhancement has been observed consistently in skeletal muscles following active stretching. However, its underlying mechanism(s) remain elusive, and it cannot be explained readily within the framework of the cross‐bridge theory. Traditionally, residual force enhancement has been attributed to the development of sarcomere length non‐uniformities. However, recent evidence suggests that this might not be the case. Rather, it appears that residual force enhancement has an active and a passive component. The active component is tentatively associated with changes in the cross‐bridge kinetics that might be reflected in decreased detachment rates following active muscle stretching, while the passive component possibly originates from a structural protein, such as titin, whose stiffness might be regulated by calcium.
The Ca2+ and Rho GTPase signaling pathways underlying activity‐dependent actin remodeling at dendritic spines

Most excitatory synapses reside on small protrusions located on the dendritic shaft of neurons called dendritic spines. Neuronal activity regulates the number and structure of spines in both developing and mature brains. Such morphological changes are mediated by the modification of the actin cytoskeleton, the major structural component of spines. Because the number and size of spines is tightly correlated with the strength of synaptic transmission, the activity‐dependent structural remodeling of a spine plays an important role in the modulation of synaptic transmission. The regulation of spine morphogenesis utilizes multiple intracellular signaling pathways that alter the dynamics of actin remodeling. Here, we will review recent studies examining the signaling pathways underlying activity‐dependent actin remodeling at excitatory postsynaptic neurons. © 2012 Wiley Periodicals, Inc