Miracle-dz/UniFAR-FTUs huggingface dataset:
Effectiveness of an Evidence-Based Quality Improvement Approach to Cultural Competence Training: The Veterans Affairs' “Caring for Women Veterans” Program

Introduction: Although providing culturally sensitive health care is vitally important, there is little consensus regarding the most effective strategy for implementing cultural competence trainings in the health care setting. Evidence-based quality improvement (EBQI), which involves adapting evidence-based practices to meet local needs, may improve uptake and effectiveness of a variety of health care innovations. Yet, to our knowledge, EBQI has not yet been applied to cultural competence training. To evaluate whether EBQI could enhance the impact of an evidence-based training intended to improve veterans affairs health care staff gender sensitivity and knowledge (Caring for Women Veterans; CWV), we compared the reach and effectiveness of EBQI delivery versus standard web-based implementation strategies of CWV and assessed barriers and facilitators to EBQI implementation. Methods: Workgroups at four diverse veterans affairs health care sites were randomized to either an EBQI or standard web-based implementation condition (SI). All EBQI sites selected a group-based implementation strategy. Employees (N = 84) completed pretraining and posttraining assessments of gender sensitivity and knowledge, and focus groups/interviews were conducted with leadership and staff before and after implementation. Results: Reach of CWV was greater in the EBQI condition versus the SI condition. Whereas both gender sensitivity and knowledge improved in the EBQI condition, only gender sensitivity improved in the SI condition. Qualitative analyses revealed that the EBQI approach was well received, although a number of barriers were identified. Discussion: Findings suggest that EBQI can enhance the uptake and effectiveness of employee trainings. However, the decision to pursue EBQI must be informed by a consideration of available resources.
A cross-country comparative analysis of e-government service delivery among Arab countries

Much of the existing e-government research focuses on developed countries. Although a relatively small number of studies explored Arab e-government development, they did so in a single country context. This article provides an insight into the current state of Arab e-government developments. A cross-country comparative analysis of e-government Web sites and portals was conducted on 16 Arab countries to assess their development stages in e-government service delivery capability. Further comparative analysis was performed between the top Arab e-governments and the global top e-governments in developed countries with regard to “e-democracy,” often the highest level e-government service delivery capability identified in the literature. The results confirm a wide digital divide that remains between the Arab countries and the leading developed countries. Importantly, however, the results also show a wide digital divide even among the Arab countries studied, particularly in the development of advanced e-government service delivery capabilities. These results have important implications for developing countries in managing both economic and non-economic resources effectively for successful e-government development. © 2009 Wiley Periodicals, Inc.
Enhancement and Analysis of Conversational Speech: JSALT 2017

Automatic speech recognition is more and more widely and effectively used. Nevertheless, in some automatic speech analysis tasks the state of the art is surprisingly poor. One of these is “diarization”, the task of determining who spoke when. Diarization is key to processing meeting audio and clinical interviews, extended recordings such as police body cam or child language acquisition data, and any other speech data involving multiple speakers whose voices are not cleanly separated into individual channels. Overlapping speech, environmental noise and suboptimal recording techniques make the problem harder. During the JSALT Summer Workshop at CMU in 2017, an international team of researchers worked on several aspects of this problem, including calibration of the state of the art, detection of overlaps, enhancement of noisy recordings, and classification of shorter speech segments. This paper sketches the workshop's results, and announces plans for a “Diarization Challenge” to encourage further progress.
Focal right inferotemporal atrophy in AD with disproportionate visual constructive impairment

Objective: To explore the structural neuroimaging correlates of visual constructive impairment in patients with mild to moderate Alzheimer disease (AD). Background: There is considerable heterogeneity in the non-memory cognitive deficits associated with AD. Structural neuroimaging with MRI is an important diagnostic tool that is gaining acceptance as a surrogate measure of brain pathology in AD treatment trials. Most MRI measurements have focused on medial temporal lobe or global cortical atrophy, which may not reflect some important clinical features of AD. Methods: Thirty-two patients with probable AD were stratified into two groups based on their relative performance on a visual constructive task, the copy of a modified Rey-Osterrieth figure (Rey). The two groups did not differ in basic demographic features or in neuropsychological performance, other than on the visual constructive task. MRI measurements of hippocampal volume, cortical gray matter volume, and focal cortical gray matter loss were performed in the patients and a group of 71 age-matched, normal controls. Results: Both groups showed significant, bilateral hippocampal as well as cortical gray matter volume loss relative to controls. The more spatially impaired AD group (SAD) had more right than left cortical gray matter loss, whereas the opposite was true in the less spatially impaired group (NSAD). The SAD group had significantly less gray matter in the right inferior temporal gyrus relative to the NSAD group. Atrophy of this region was correlated with performance on the Rey task in all patients with AD. Conclusions: Right inferotemporal atrophy may serve as a neuroimaging marker of visual constructive impairment in mild to moderate AD. Heterogeneous cortical atrophy is a common feature of AD.
Sleep across chemotherapy treatment: a growing concern for women older than 50 with breast cancer.

PURPOSE/OBJECTIVES To conduct a metasynthesis of human sleep studies that included women aged 50 years and older with breast cancer across chemotherapy treatment. DATA SOURCES English publications were searched with the terms sleep and breast cancer via Ovid, PubMed, and EBSCO-host databases. Human studies that used sleep-specific instruments published from January 1974-May 2009 were included. Intervention studies also were included if they provided baseline sleep data. Studies that used quality-of-life or symptom instruments or in which patients were prescreened for insomnia were not included. DATA SYNTHESIS 382 publications were found; 17 met inclusion criteria, and 3 additional studies were located from the literature on fatigue. Two articles reported on the same study, so a total of 19 studies were included in the review. In women with nonmetastatic breast cancer, subjective and objective sleep quality appear to be poor and nocturnal awakenings frequent across chemotherapy treatment. Daytime sleepiness increases in the active phase of chemotherapy, and insomnia symptoms are common before and following chemotherapy treatment. In women with recurrent or metastatic breast cancer, difficulty falling asleep, nocturnal awakenings, difficulty awakening, and daytime sleepiness are problematic at different points in chemotherapy treatment. CONCLUSIONS Sleep for women, including those older than 50 years, appears to be impaired across chemotherapy treatment, although replication of findings is very limited. IMPLICATIONS FOR NURSING Future research should investigate sleep in specific age and minority groups, include daytime sleep and sleepiness, and use standard sleep nomenclature and objective measures.
Vision interaction method based on visual attention mechanism

This paper puts forward a calibration-free vision interaction system using Visual Attention Mechanism (VAM), which requires the user to watch a video clip in advance to alleviate the problem of cumbersome and unnatural calibration, which exists in traditional gaze estimators. Our method establishes the mapping between eye features and gaze points using Support Vector Machine (SVM), in which eye features are constructed using Pupil Center Cornea Reflection (PCCR) vectors and gaze points are found using saliency maps. The experimental results show an increase in gaze estimator accuracy and and the vision interaction applications show the applicability of the vision interaction system.
Molecular and morphological characterization of the cercariae of Lecithodendrium linstowi (Dollfus, 1931), a trematode of bats, and incrimination of the first intermediate snail host, Radix balthica

SUMMARY Lecithodendrium linstowi is one of the most prevalent and abundant trematodes of bats, but the larval stages and intermediate hosts have not been identified. We present the first molecular and morphological characterization of the cercariae of L. linstowi based on a phylogenetic analysis of partial fragments of LSU and ITS2 rDNA. The first intermediate host was incriminated as Radix balthica by DNA barcoding using cox1 and ITS2 sequences, although the snail morphologically resembled Radix peregra, emphasizing the requirement for molecular identification of lymnaeids as important intermediate hosts of medical and veterinary impact. The application of molecular data in this study has enabled linkage of life cycle stages and accurate incrimination of the first intermediate host.
Examining the Relationship of an All-Cause Harm Patient Safety Measure and Critical Performance Measures at the Frontline of Care

Background In 2015, the Institute of Medicine Vital Signs report called for a new patient safety composite measure to lessen the reporting burden of patient harm. Before this report, two patient safety organizations had developed an electronic all-cause harm measurement system leveraging data from the electronic health record, which identified and grouped harms into five broad categories and consolidated them into one all-cause harm outcome measure. Objectives The objective of this study was to examine the relationship between this all-cause harm patient safety measure and the following three performance measures important to overall hospital safety performance: safety culture, employee engagement, and patient experience. Methods We studied the relationship between all-cause harm and three performance measures on eight inpatient care units at one hospital for 7 months. Results The findings demonstrated strong correlations between an all-cause harm measure and patient safety culture, employee engagement, and patient experience at the hospital unit level. Four safety culture domains showed significant negative correlations with all-cause harm at a P value of 0.05 or less. Six employee engagement domains were significantly negatively correlated with all-cause harm at a P value of 0.01 or less, and six of the ten patient experience measures were significantly correlated with all-cause harm at a P value of 0.05 or less. Conclusions The results show that there is a strong relationship between all-cause harm and these performance measures indicating that when there is a positive patient safety culture, a more engaged employee, and a more satisfying patient experience, there may be less all-cause harm.
Good and Bad Days: Fluctuations in the Burden of Informal Dementia Caregivers, an Experience Sampling Study

Background Informal dementia caregivers (IDCs) are often confronted with important fluctuations in care-related burden, commonly described as “good and bad days. ” These fluctuations are overlooked by traditional questionnaires focusing on the average experience. The experience sampling method (ESM) is based on the repeated collection of data in everyday life, thereby allowing the description of day-to-day fluctuations in IDC burden, and the identification of their correlates. ESM studies are still scarce among IDCs, with none focusing on day-to-day fluctuations in burden. Objectives This ESM study aimed to examine day-to-day fluctuations in the burden of IDCs and test their associations with six moment-to-moment predictors. Methods Primary IDCs (N = 26, median age = 68 years, 77% women, 73% spouses) volunteered to answer questions about their daily burdens, patients’ memories and behavioral problems (MBP), caregivers’ MBP-related distress, psychological distress, self-efficacy and positive affects, and relationship quality; volunteers did this every evening for 2 weeks on a touchpad, resulting in 206 measures. Data were analyzed with multilevel linear regression. Results Day-to-day fluctuations covered about two thirds of the total variance for most study variables. All six predictors had a significant bivariate relation with daily burden, explaining 15%–32% of its fluctuations, with significant differences between caregivers in the strength of these relations. The best multivariate model explained 51% of the day-to-day fluctuations in burden. It included caregiver MBP-related distress, psychological distress, and relationship quality. Discussion This innovative study of IDC burden shows that day-to-day fluctuations are an important part of caregivers’ real-life experiences and that half of this variability is predicted by currently understudied factors. Inviting caregivers to monitor clinical outcomes daily over 1 or 2 weeks could help tailor interventions to their individual needs and also empower them.
Spatial-temporal traffic speed bands data analysis and prediction

The development of Intelligent Transportation System (ITS) requires insightful information and predictions from spatial-temporal traffic data. In order to improve commuters' experiences by forecasting and proactively taking actions on city traffic, in this paper, we analysed temporal and spatial patterns of low-resolution traffic speed bands and predicted future traffic status based on SVM learning models. Real speed bands data of Singapore were used for analysis and prediction. The performance of machine learning models were evaluated by speed bands data of road segments in Central Business Districts (CBD) and Tampines area at Singapore. The results demonstrated that multiple kernel learning (MKL) combining both temporal and spatial patterns showed better performance in predicting next 5 minutes and 1 hour traffic conditions in both CBD and rural areas (Tampines). In short-term prediction (next 5 minutes), SVM learning using temporal pattern showed better performance in both CBD and Tampines than using spatial patterns. However, the long-term prediction (next 1 hour) of CBD area has lower accuracy than rural area (Tampines). In general, we can achieve up to 88% prediction accuracy of traffic speed band at entire Singapore.
The auditory-vocal-respiratory axis in birds.

A series of studies is described which in general aim to identify two sets of neural linkages in the brain and spinal cord of songbirds and non-songbirds, these avian types differing along a dimension of 'complexity of vocal communication'. One set of linkages is postulated to link the vocal system with the respiratory system, since birds, like humans, require controlled expiration in order to vocalize normally. The other set is thought to link the auditory system with the vocal system, at least in songbirds, because they are dependent upon auditory feedback for vocal learning. The systems and their linkages can be regarded as forming an 'auditory-vocal-respiratory axis', around which the animal's communication system evolves and revolves. The experimental strategy used was one which began at the periphery (the abdominal expiratory muscles), then progressively identified more central neural structures using retrograde transport methods in partial combination with recordings of single cell activity. The projections delineated by these methods were then defined in detail by anterograde tracing methods. The results of the studies confirmed the expectation that the vocal and respiratory systems have many neural elements in common. They also suggested that songbirds and non-songbirds possess similar neural pathways in the brainstem and spinal cord for the control of both vocalization and respiration but indicated that there may be significant differences between the two types of birds in the degree to which the telencephalon is able to modulate respiratory-vocal activity downstream. Thus, whereas there is a cascade of descending projections terminating upon syringeal and laryngeal motoneurons and expiratory premotor neurons in both songbirds and non-songbirds, the most rostral origin of this cascade is the telencephalic nucleus robustus archistriatalis in (male) songbirds but, apparently, the dorsomedial nucleus of the intercollicular complex of the midbrain (DM) in pigeons. Connectional studies of the auditory system in pigeons delineated a series of projections which originate in Field L2, the primary telencephalic auditory area, and leave the telencephalon via the nucleus archistriatum intermedium, pars medialis (Aivm), after traversing a minimum of three synapses within the telencephalon. (ABSTRACT TRUNCATED AT 400 WORDS)
AMS Three–Piece Inflatable Implants for Erectile Dysfunction: A Long–Term Multi–Institutional Study in 200 Consecutive Patients

Objectives: The aim of this study was to assess the longterm mechanical reliability of AMS (American Medical Systems) three–piece inflatable implants and their impact on patient–partner satisfaction in 200 consecutive patients with erectile dysfunction who underwent surgery in five different institutions.Methods: Patient charts included in the study were collected and extensively assessed to record pre– and intraoperative data and postoperative complications. All patients and 120 partners were then seen often in the office at a mean follow–up of 59 months (range 6–130) and they were extensively questioned about function of the device and its impact on the couple’s sexual life.Results: At the long–term follow–up, 185 patients (92.5%) were still engaging in sexual intercourse with a mean frequency of 1.7/week. Patients and partners reported prosthetic erections as excellent, satisfactory or poor in 96 (48%), 100 (50%) and 4 (2%) cases, and in 20 (17%), 80 (66%) and 20 (17%) cases, respectively. Postoperative sexual activity was considered excellent, satisfactory or poor by 140 (70%), 44 (22%) and 16 (8%) patients and by 34 (28%), 81 (68%) and 5 (4%) partners, respectively. Reasons for patients’ complaints included postoperative penile shortening in 60 (30%) cases and poor glandular engorgement in 40 (20%) cases. Partners’ main complaint was unnaturalness of the prosthetic erection, a factor reported by 30 (25%) subjects. Complications requiring surgical exploration included infection in 12 patients (6%) and mechanical failure in 8 patients (4%). Kaplan–Meier estimates demonstrated significantly decreased mechanical survival for the Ultrex type of cylinders compared to the CX type of cylinders.Conclusions: AMS three–piece inflatable implants provide an overall patient and partner satisfaction rate of 92 and 96%, respectively. However, postoperative penile shortening and poor glandular engorgement were the causes of some complaints among the patient population as well as the unnaturalness of prosthetic erection among female partners. In the long–term, mechanically speaking, CX cylinders seem to be more reliable than the Ultrex ones.
Structural insights into the mechanisms of CNBD channel function

Cyclic nucleotide-binding domain (CNBD) channels are a family of ion channels in the voltage-gated K+ channel superfamily that play crucial roles in many physiological processes. CNBD channels are structurally similar but functionally very diverse. This family includes three subfamilies: (1) the cyclic nucleotide-gated (CNG) channels, which are cation-nonselective, voltage-independent, and cyclic nucleotide-gated; (2) the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, which are weakly K+ selective, hyperpolarization-activated, and cyclic nucleotide-gated; and (3) the ether-à-go-go-type (KCNH) channels, which are strongly K+ selective, depolarization-activated, and cyclic nucleotide-independent. Recently, several high-resolution structures have been reported for intact CNBD channels, providing a structural framework to better understand their diverse function. In this review, we compare and contrast the recent structures and discuss how they inform our understanding of ion selectivity, voltage-dependent gating, and cyclic nucleotide–dependent gating within this channel family.
Accurate PCR Detection of Influenza A/B and Respiratory Syncytial Viruses by Use of Cepheid Xpert Flu+RSV Xpress Assay in Point-of-Care Settings: Comparison to Prodesse ProFlu+

ABSTRACT The Xpert Flu+RSV Xpress Assay is a fast, automated in vitro diagnostic test for qualitative detection and differentiation of influenza A and B viruses and respiratory syncytial virus (RSV) performed on the Cepheid GeneXpert Xpress System. The objective of this study was to establish performance characteristics of the Xpert Flu+RSV Xpress Assay compared to those of the Prodesse ProFlu+ real-time reverse transcription-PCR (RT-PCR) assay (ProFlu+) for the detection of influenza A and B viruses as well as RSV in a Clinical Laboratory Improvement Amendments (CLIA)-waived (CW) setting. Overall, the assay, using fresh and frozen nasopharyngeal (NP) swabs, demonstrated high concordance with results of the ProFlu+ assay in the combined CW and non-CW settings with positive percent agreements (PPA) (100%, 100%, and 97.1%) and negative percent agreements (NPA) (95.2%, 99.5%, and 99.6%) for influenza A and B viruses and RSV, respectively. In conclusion, this multicenter study using the Cepheid Xpert Flu+RSV Xpress Assay demonstrated high sensitivities and specificities for influenza A and B viruses and RSV in ∼60 min for use at the point-of-care in the CW setting.
Anticoagulant-antithrombin and fibrinolytic actions of extract of marine alga Corallina rubens L.

The extract of Corallina rubensL. and its fractions were studied chemically, and their effects on the coagulation and fibrinolytic systems were investigated.Thin-layer and paper chromatographic studies of these fractions showed a polypeptide structure. One of them (fraction I) contains a sugar component consisting of 7 different monosaccharides. Antithrombin activity The extract of C. rubens and its fractions were examined in regard to their actions on coagulation and fibrinolysis. The anticoagulant-antithrombin effect of fraction I was found to be more powerful than that of the extract and of fraction III. Fraction I also had an inhibitory effect on fibrinolysis. The sum of these activities in the total extract of C. rubens was an activator action on fibrinolysis with an anticoagulant-antithrombin effect. The fibrinolysis-activating effects were found in fraction II and fraction III.