Miracle-dz/UniFAR-FTUs huggingface dataset:
Silicon consumption kinetics by marine sponges: An assessment of their role at the ecosystem level

The silicic acid (DSi) is a dissolved nutrient used by diverse marine organisms to build their skeletons of biogenic silica (BSi). This consumption, mostly due to diatoms, largely determines the availability of DSi in the photic ocean. Yet growing evidence suggests that Si consumers traditionally disregarded, such as the siliceous sponges, may also play a role. This study investigated the kinetics of DSi utilization by two demosponges as a function of both DSi availability and duration of the incubation period (24 h vs. 48 h). Consumption increased with increasing DSi availability following a saturable Michaelis–Menten kinetics. Haliclona simulans saturated at about 70 μM (Km = 45.9) and Suberites ficus around 130 μM (Km = 108.2). Forty‐eight hour incubations yielded more conservative consumption rates than 24 h incubations, particularly when DSi availability was far below saturation. DSi concentrations in the sponge natural habitats (0.2–15 μM) were consistently much lower than required for efficient elaboration of the BSi skeleton, suggesting a chronic DSi limitation. The DSi consumption kinetics was combined with quantifications of sponge biomass in the Bay of Brest (France), which was used as case study. In this system, sponges consume daily 0.10 ± 0.19 mmol Si m−2 and about 6.4 × 106 mol Si yearly. This activity represents 7.6% of the net annual BSi production in the Bay, a figure overlooked in previous nutrient balances based only on diatoms. Since the world marine Si cycle does not yet incorporate the contribution of sponges, its global BSi production budget may also be underestimated.
Functional capacity of diabetic older adults living in a municipality in Northeastern Brazil

— Diabetes Mellitus is a disease that contribute to the loss of functional capacity in older adults. This study aimed to measure diabetic older adults’ functional capacity for activities of daily living (ADL) and instrumental activities of daily living (IADL). We carried out a descriptive and analytical cross-sectional study with older adults aged 65+ years at a specialized health care center of Brazil. The medical records of the patients were selected using non-probability sampling. In this study was found, significantly statistical, higher prevalence in ADL among persons aged 75+ years, those with low levels of education and relation between self-rated current health status. For dependence in IADL, it was common among 75+ years old people, those with lower levels of education, with income of up to 2 minimum wages and worse self-rated health. There is a need to work on public policies that contribute to active and successful aging by promoting the autonomy and functional independence of older adults in the household and community.
Diversity Analysis and Assessment of Association of SSR Markers to Late Leaf Spot and Rust Resistance in Groundnut (Arachis hypogaea L.)

Groundnut (Arachis hypogaea L.) is one of the most important oilseed crops belonging to legume family Fabaceae. The main economic part is seed and is valued for its polyunsaturated fatty acid containing oil with longer shelf life. Groundnut is a segmental allopolyploid originated recently from a cross between two diploid species and spontaneous doubling of chromosomes (Halward et al., 1991; Young et al., 1996 and Seijo et al., 2004) indicating its narrow genetic base and low levels of genetic diversity for desired alleles creating constrains in conventional breeding programmes.
"Individual’s DNA Repair Capacity and COVID-19: Let’s Take One Step Back to understand it"

Editorial The outbreak of novel coronavirus from Wuhan, Hubei Province, China has brought turbulence in the entire world. On January 9, 2020; World Health Organization reported that Chinese authorities had identified a novel strain of coronavirus. Each and every country and its authorities are taking major steps to avoid the spread of this pandemic situation. Coronavirus pandemic has disrupted the economy of many countries by hampering business, airline industry, stock market, tourism, and several more. The spread of the virus among humans has demonstrated a wide range of differences in susceptibility. Many individuals get infected by virus or remain asymptomatic or are carriers of it. Immunity, self-hygiene, and civic sense play a pivotal role to avoid getting infected in this scenario of existing overburden in the medical field.
High Genetic Diversity and Connectivity Among Populations of Quercus candicans, Quercus crassifolia, and Quercus castanea in a Heterogeneous Landscape in Mexico

Oaxaca state is one of the main hotspots of biodiversity in Mexico, containing almost 40% of the Mexican vascular flora, due to its high variability in habitat and climatic conditions coupled with high elevations in mountains and low elevations in valleys. We studied the genetic diversity and population structure of Quercus candicans, Quercus crassifolia, and Quercus castanea across their geographical distribution in Oaxaca state to understand how the heterogeneous physiography had driven the genetic diversity and population differentiation in these three oak species. We found high levels of genetic diversity but ca. 40% of the populations had significant values of Wright’s inbreeding coefficient. The analysis of molecular variance indicated that most of the variation occurred within populations in the three oak species. Resistance analyses showed connectivity among almost all the populations but barrier analysis found genetic breaks that limited gene flow among some populations of the oak species. Even in a heterogeneous environment such as in Oaxaca state, the oak species still have high levels of genetic diversity and landscape connectivity. However, it is necessary to maintain the genetic connectivity through the preservation of natural corridors with forests in good condition, which is necessary to maintain the cohesiveness of the species in the long term. It is also important to protect the centers of species diversity in Oaxaca state located in the subprovinces of Western Oaxacan Mountains and Valleys, Sierra Madre de Oaxaca, and Sierra Madre del Sur because they harbor most of the population genetic diversity and oak species richness, as has been shown in previous studies.
Patients’ Level of Satisfaction from Pharmaceutical Services Provided by Private Pharmacies Using the SERVQUAL Model Analysis

Customer satisfaction is an essential aspect of quality of service. In healthcare, customer satisfaction, also known as patient satisfaction is an indicator for measuring the quality of service and how happy the patient is with the professional services received in the industry. This parameter is essential for all healthcare organizations, as it is used for improving service delivery and strategic goals. Therefore, this study aimed to examine the patients’ level of satisfaction regarding professional pharmaceutical services provided by certi ied pharmacists of 14 private pharmacies in the Kasihan Subdistrict, Bantul Regency, Special Region of Yogyakarta, Indonesia. The nonexperimental descriptive design with a cross-sectional methodwas employed in this study. It involved 308 participants and was conducted from November 2018 to May 2019. The patients’ level of satisfaction was measured using the Service Quality (SERVQUAL) approach involving ive dimensions, namely; reliability, responsiveness, assurance, empathy, and tangibles. The results showed that the patients’ level of satisfaction on the average was satisfactory, at 80.2%. Besides, satisfaction based on reliabilitywas 82.5%, responsiveness was 85.5%, assurance was 85.8%, empathy was 76.3%, while the dimension of tangibles was 70.9%. In conclusion, patients were satis ied on an average, regarding the professional services provided by the staff of certi ied pharmacies in the region.
Grammatical Gender Effects on Cross-linguistic Categorization

This article examines the effect that the terms used to describe grammatical gender (e.g., “masculine”) and “feminine”) have on a speaker’s perception of how the marked lexical item may be classified. The overt classification can manifest itself in subconscious ways. For example, if shown a picture of a key and asked if it were in a cartoon if the voice would be a male or female, often speakers assign the voice based on how the noun is marked in their language: masculine in German and feminine in Spanish. Further study is needed working with bilingual speakers or gender-marking languages and studies are needed that control of level of proficiency to see if the same effect is present for second language learners regardless of if L1 marks grammatical gender or not. It is clear that there is a categorization bias for gendermarking languages, but further study is required to control for variables that could contribute to the phenomenon.
Starting from the Influence of Tobacco: AKR1C3 and COVID-19 Receptor ACE2 Are Potential Pprognostic Biomarkers for Brain Lower Grade Glioma, Evidence from Bioinformatics Analyses

Background: Coronavirus disease (COVID-19) related pneumonia is leaded by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which infects host cells through receptors named Angiotensin-converting enzyme 2 (ACE2). Smoking is thought to be related to poor disease prognosis, as a large amount of evidence highlights the negative effects of smoking on lung health and its causal relationship with various respiratory diseases. Methods: We first evaluated the role of ACE2 expression level with tobacco effect. And correlation analyses were used to identify the related genes of ACE2 both in smoker trait and human normal multi-tissues. After intersections, hub genes were later used to further GSEA and co-regulated mechanisms were explored by GeneMANIA. We used UALCAN to perform survival curves of pan-cancers included 33 types of cancers. New clinical model of top co-occurrence cancer type was constructed and validated. Results: Effected by cigarette smoking, the expression level of ACE2 expressed statistically upwards in current smokers compared with never smokers, upwards in groups after acute smoke exposed compared with normal control. But no strong evidence detected in third-hand smoke, as poor amounts of samples, only 4. A little trend of expressing upwards became in groups after third-hand smoke compared with groups after clean air exposing. 4 genes included PIR, ADH7, AKR1C2 and AKR1C3 were identified as ACE2 related genes in smoker trait and human normal multi-tissues. Then, we made the survival curves of pan-cancers in 4 genes. Brain lower grade glioma was the co-occurrence type as both ACE2, PIR and AKR1C3 had the significantly prognostic situation. Later, we made the new clinical prediction model as the C-index was 0.827 and the Area Under Curves (AUCs) of 1-year survival, 2-year survival and 3-year survival were 0.921(95%CI, 0.882-0.961), 0.911(95%CI, 0.860-0.962) and 0.878(95%CI, 0.818-0.939). In inner validation, the AUCs of 1-year survival, 2-year survival and 3-year survival were 0.777(95%CI, 0.640-0.914), 0.916(95%CI, 0.842-0.990) and 0.888(95%CI, 0.768-1.000). In outer validation one, the AUCs of 1-year survival, 2-year survival and 3-year survival were 0.764(95%CI, 0.672-0.856), 0.848(95%CI, 0.783-0.913) and 0.748(95%CI, 0.656-0.841). And in outer validation two the AUCs of 1-year survival, 2-year survival and 3-year survival were 0.740(95%CI, 0.654-0.826), 0.766(95%CI, 0.688-0.843) and 0.794(95%CI, 0.721-0.866). Conclusions: In our study, we compared the ACE2 expression level between smokers and non-smokers crowds and identified associated hub genes. Then we explored the further role of hub genes in tumor fields to identify the correlation and influence between the avoidable host factors such as smoking on COVID-19 contamination and tumor. ACE2 and AKR1C3 are potential prognostic genes for brain lower grade glioma, and we created the web dynamic nomogram and encapsulation app through validations.
Does technical assessment matter? Functionality and usability testing of websites for ESL/EFL autonomous learners

Research in Learning Technology 2020. © 2020 N. Aguayo-Arrabal and C.M. Ramírez-Delgado. Research in Learning Technology is the journal of the Association for Learning Technology (ALT), a UK-based professional and scholarly society and membership organisation. ALT is registered charity number 1063519. http://www.alt. ac.uk/. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for any purpose, even commercially, provided the original work is properly cited and states its license.
Connecting the Microenvironmental Niche to Treatment Response in Ovarian Cancer

Ovarian cancer has the highest mortality rate of all gynecologic cancers, which may be attributed to an often late stage diagnosis, when the cancer is already metastatic, and rapid development of treatment resistance. We propose that the metastatic disease could be better characterized by observing interactions within the microenvironmental niche of the primary site that shapes the tumor’s early phenotypic progression. We present a mechanistic mathematical model of ovarian cancer that considers spatial interactions between tumor cells and several key stromal components. We demonstrate how spatial biomarker imaging data from the primary tumor can be analyzed to define a patient-specific microenvironment in the mathematical model. We then show preliminary results, using this model, that demonstrate how differences in the niche composition of a tumor affects phenotypic evolution and treatment response.
Target Value Delivery in Bid Process

The use of the traditional tendering procedure is predominant in the construction industry; although it is ill-equipped for the current complex and dynamic nature of the industry. Various Lean construction scholars have noted that while construction clients are demanding for more complex and dynamic projects, there is a need to transform the traditional tendering procedure which focuses on the lowest cost for the selection of contractors, while neglecting their technical and management qualifications to one that focuses on needs and requirement of the project. Collaborative approaches like Target Value Design (TVD) can be incorporated in the tendering procedure to ensure that the project needs are met. The case study method was used to demonstrate how TVD principles were used to make competing companies collaborate and contribute during the pre-tender selection process in the traditional tendering procedure to improve project outcomes. Semi-structured interviews were conducted with 17 professionals who participated in 2 case study projects. The study provides empirical data showing that the incorporation of TVD mitigates the reported challenges of the traditional tendering process. Cost reduction/certainty, reduction of waste/rework/variation, stakeholders’ satisfaction, accurate cost specifications, early involvement of stakeholders, tenderer’s competency and identification of problems were some of the benefits identified.
Message Strategies and Media Formats of Florists’ Facebook Posts and Their Effects on Users’ Engagement Behaviors

Social media marketing has been widely adopted by florists with the use of the Facebook brand page. However, many florists fail to achieve their expected success in that realm because of not being fully conversant in posting on social media. To address this deficiency, this study aims to 1) develop a taxonomy of florists’ Facebook posts to clarify florists’ message strategies on Facebook brand page and 2) investigate the effect of posted messages and media formats on the marketing performance of florists’ Facebook brand pages by evaluating users’ engagement based on the number of likes, comments, and shares from users for each post. Using data derived from 1646 empirical Facebook posts initiated by florists, it was found that florists’ Facebook posts could be classified into four broad message types covering 12 categories. The statistical results for analysis of variance (ANOVA) and post hoc tests revealed that the posted message and media format had significant effects in terms of causing users to like, comment on, or share florists’ posts. Compared with other message categories, posts in the message categories of product information, gratitude to customers, and holiday greetings had more favorable effects in terms of causing users to like, comment on, or share florists’ posts. As for the effect of media format, it was the posts in the photo media format that attracted more likes, comments, and shares from users compared with those in other media formats. Florists who operate brand pages on Facebook can be guided by our research when making decisions regarding the post characteristics in message orientations and media formats for attracting favorable responses from users.
Construcciones relativas en lenguas yuto-aztecas de la Sierra Tarahumara: una panorámica intra-genética con atención al yaqui

espanolEste trabajo representa una contribucion tipologica al analizar las clausulas relativas en lenguas yuto-aztecas habladas durante centurias en el area geografica de la Sierra Tarahumara en el noroeste mexicano (pima bajo, tepehuano del norte, tarahumara y guarijio, aunque por fines comparativos tambien se alude al yaqui). Las clausulas relativas que se encuentran en estas lenguas son nominalizadas o no-nominalizadas. Las evidencias comparativas demuestran que los relativizadores o subordinantes presentes en al menos tres de estas lenguas tuvieron su origen en elementos demostrativos y que los sujetos genitivos, rasgo de la nominalizacion clausal, estan por desaparecer en dos de estas lenguas. Este hecho implica un cambio diacronico hacia las construcciones finitas. EnglishThis paper makes a typological contribution by describing relative clauses in Uto-Aztecan languages spoken, by centuries, in a geographical area of northwestern Mexico, known as the Sierra Tarahumara (Pima Bajo, Northern Tepehuan, Tarahumara and Guarijio, although for comparative purposes Yaqui is also considered). Relative clauses observed in these languages show that they are nominalized or non-nominalized. Comparative evidences available for the analysis reveals that the relativizers or subordinators observed in at least three of the languages come from demonstrative elements, and that genitive subjects, one of the main properties of clausal nominalizations are disappearing in two of the languages. This fact implies a diachronic change to finite constructions.
An attribute‐diversity approach to functional diversity, functional beta diversity, and related (dis)similarity measures

Based on the framework of attribute diversity (a generalization of Hill numbers of order q), we develop a class of functional diversity measures sensitive not only to species abundances but also to trait‐based species‐pairwise functional distances. The new method refines and improves on the conventional species‐equivalent approach in three areas: (1) the conventional method often gives similar values (close to unity) to assemblages with contrasting levels of functional diversity; (2) when a distance metric is unbounded, the conventional functional diversity depends on the presence/absence of other assemblages in the study; (3) in partitioning functional gamma diversity into alpha and beta components, the conventional gamma is sometimes less than alpha. To resolve these issues, we add to the attribute‐diversity framework a novel concept: τ, the threshold of functional distinctiveness between any two species; here, τ can be chosen to be any positive value. Any two species with functional distance ≥ τ are treated as functionally equally distinct. Our functional diversity quantifies the effective number of functionally equally distinct species (or “virtual functional groups”) with all pairwise distances at least τ for different species pairs. We advocate the use of two complementary diversity profiles (τ profile and q profile), which depict functional diversity with varying levels of τ and q, respectively. Both the conventional species‐equivalent method (i.e., τ is the maximum of species‐pairwise distances) and classic taxonomic diversity (i.e., τ is the minimum of non‐zero species‐pairwise distances) are incorporated into our proposed τ profile for an assemblage. For any type of species‐pairwise distance matrices, our attribute‐diversity approach allows proper diversity partitioning, with the desired property gamma ≥ alpha and thus avoids all the restrictions that apply to the conventional diversity decomposition. Our functional alpha and gamma are interpreted as the effective numbers of functionally equally distinct species, respectively, in an assemblage and in the pooled assemblage, while beta is the effective number of equally large assemblages with no shared species and all species in the assemblages being equally distinct. The resulting beta diversity can be transformed to obtain abundance‐sensitive Sorensen‐ and Jaccard‐type functional (dis)similarity profiles. Hypothetical and real examples are used to illustrate the framework. Online software and R codes are available to facilitate computations.
Parent Support of Mexican-Descent High School Adolescents’ Science Education: A Culturally Grounded Framework

The aim of this study was to use sociocultural perspectives to elaborate on Eccles’ parent socialization model and create a culturally grounded, multidimensional model of parent support among Mexican-descent families. Given Latinx underrepresentation in science, technology, engineering, and mathematics careers, we focus on science as an important domain in which to study parent support. Using a qualitative approach, this study examines (a) what forms of parent science support do Mexican-descent parents and adolescents perceive as best practices and (b) what are the social, cultural, and contextual barriers parents face and in what ways do parents continue to support their adolescents in science in spite of those barriers? Seventy-four parent (mean age: 40 years; 23% U.S.-born and 77% Mexico-born) and 73 adolescent (mean age: 15 years; 41% female) nterviews were analyzed using inductive and deductive approaches. Findings suggest that parents use traditional and nontraditional culturally grounded forms of support: involvement at home, providing words of encouragement (e.g., échale ganas), and leveraging resources (e.g., kin support). Participants felt work-related barriers, linguistic barriers, and limited science knowledge shaped parents’ support. Results highlight the unique ways parents support their adolescents’ science education as well as the need for educators to consider how parents’ sociocultural experiences shape their support.
Structure and genome ejection mechanism of Podoviridae phage P68 infecting Staphylococcus aureus

Phages infecting S. aureus have the potential to be used as therapeutics against antibiotic-resistant bacterial infections. However, there is limited information about the mechanism of genome delivery of phages that infect Gram-positive bacteria. Here we present the structures of S. aureus phage P68 in its native form, genome ejection intermediate, and empty particle. The P68 head contains seventy-two subunits of inner core protein, fifteen of which bind to and alter the structure of adjacent major capsid proteins and thus specify attachment sites for head fibers. Unlike in the previously studied phages, the head fibers of P68 enable its virion to position itself at the cell surface for genome delivery. P68 genome ejection is triggered by disruption of the interaction of one of the portal protein subunits with phage DNA. The inner core proteins are released together with the DNA and enable the translocation of phage genome across the bacterial membrane into the cytoplasm.