Miracle-dz/UniFAR-FTUs huggingface dataset:
Critical Success Factors in Online Retail – An Application of Quality Function Deployment And Interpretive Structural Modeling

The retail infrastructure has witnessed a transformation with the rapid growth of electronic commerce, especially in the last two decades. E-business all over the world has become a popular medium for buyer-seller transaction as a means that complements and supplements the experiences of a physical store. Although the application of technology-based online retail services has grown rapidly in recent years, an understanding to attract, retain, and satisfy customers in such contexts remains limited. A marketer often encounters the difficulty of constituting a framework that could be used for constructing, managing, and evaluating its service delivery through the Internet. Based on a literature review, followed by an empirical study, this paper outlines the results of a study conducted to identify the critical success factors in online retailing. The literature review helped conceptualize the variables for the study. The Quality Function Deployment Technique was applied to identify performance indicators critical to success of online retailing. These were prioritized qualitatively through Interpretive structural modeling. Such an integrated framework of critical success factors would enable a better understanding of customers’ needs and assist marketers while constructing, managing, and evaluating their online marketing strategies in the Indian context.
Dermoscopic subpatterns of ashy dermatosis related to lichen planus.

D ERMOSCOPY AIDS IN DISTINGUISHING ASHY dermatosis and hyperpigmented lichen planus (LP) lesions that tend to persist for a longer period. Figure 1A shows a violaceous papule and regressing brown macules on the forearm of a 67-year-old woman with LP. Dermoscopy of the former reveals Wickham striae (WS) surrounded by capillaries (Figure 1B). Regressing lesions reveal a structureless brown pigmentation in the absence of granularity (Figure 1C, arrows). Such a pattern favors a transient clinical course, as demonstrated in Figure 1D, which shows the disappearance of pigmentation in less than 1 year. Figure2Ashowsthetrunkofa20-year-oldwomanwith a history of LP with discoloration persisting for more than 2 years. The dermoscopic image in Figure 2B shows WS. Figure2CandDreveal regressinggraymaculeswithgranular gray-brown dots and globules (dermal melanophages) outlining WS or clustered in the depressed centers of some WS (“ashy holes”). A large amount of granules appears to indicate a slower course. These cases demonstrate that differentdermoscopicpatternsarepresent innonatrophic, regressing LP. They likely suggest a different clinical course.
Translating Evidence-Based Physical Activity Interventions for Frail Elders

SUMMARY The population shift to an older America has initiated a great deal of interest in the impact of evidence-based physical activity interventions on older adults. Physical activity for older adults has tremendous benefits and is recognized as one of the most powerful health interventions for improving seniors' ability to function and remain independent in the face of active health problems and yet the majority of all older adults remain largely sedentary. To date, few programs have been developed that apply these important research findings in physical activity to frail older adults living in the community. The purpose of this article is to review past and current trends addressing increasing physical activity in the frail elderly population at home. An exemplary model of integrating an evidence-based intervention into community-based care management programs is described. Barriers encountered when implementing evidence-based physical activity interventions with frail elderly at home and recommendations for future work in this area are discussed.
Discovering clusters in gene expression data using evolutionary approach

The combined interpretation of gene expression data and gene sequences offers a valuable approach to investigate the intricate relationships involving gene transcriptional regulation. The highly interactive expression data produced by microarray hybridization experiments allow us to find the clusters of coexpressed genes. By analyzing the upstream regions of the identified coexpressed genes, we can discover the regulatory patterns characterized by transcription factor binding sites, which govern the process of transcriptional regulation. This paper presents a generic clustering algorithm that uses a Hybrid GA approach to discover clusters in gene expression data. The advantage of this method is that large search space can be effectively explored by utilizing the evolutionary algorithm techniques. Moreover, it is able to discover underlying patterns in noisy gene expression data for meaningful data groupings, and also statistically significant patterns hidden in each cluster can be extracted at the same time. Since the proposed method can handle both continuous-and discrete-valued data, it can be used with different microarray and biomedical data. To test its effectiveness, we have used it on real expression data. The experimental results reveal meaningful groupings and uncover many known transcription factor binding sites.
Design of a Novel SS (Spread Spectrum) System based on Cooperative Communications

In this paper, we first propose a novel system that combines multi-code spread spectrum modulation (McM) technique with orthogonal frequency division multiplexing (OFDM) employing quadrature amplitude modulation (QAM). This system provides high data transmission rate without reducing spectral efficiency and overcomes the adverse effects of frequency-selective Rayleigh fading by applying a minimum mean square error (MMSE) equalizer at the receiver. Then we deploy the decode-and-forward cooperative communications protocol in the novel system to allow single-antenna users to obtain the powerful benefits of multi-antenna systems. Monte-Carlo simulations are also performed to evaluate the performance of the proposed system
Fluorescent peptide probes for in vivo diagnostic imaging

Recently, many novel peptide‐based near‐infrared (NIR) fluorescent molecular probes have been developed for in vivo biomedical imaging. To report specific information of biological targets, the probes were individually designed according to the unique property or functions of their targets. These peptide‐based probes can be classified into targeting, crosslinking, and enzyme‐activatable probes. Several of them have been tested in various in vitro and in vivo models, and the obtained imaging information has been applied to disease detection, medical diagnosis, and drug evaluations. © 2004 Wiley Periodicals, Inc. Biopolymers (Pept Sci), 2004
Enhanced CD8+ T Cell Immune Responses and Protection Elicited against Plasmodium berghei Malaria by Prime Boost Immunization Regimens Using a Novel Attenuated Fowlpox Virus1

Sterile immunity can be provided against the pre-erythrocytic stages of malaria by IFN-γ-secreting CD8+ T cells that recognize parasite-infected hepatocytes. In this study, we have investigated the use of attenuated fowlpox virus (FPV) strains as recombinant vaccine vectors for eliciting CD8+ T cells against Plasmodium berghei. The gene encoding the P. berghei circumsporozoite (PbCS) protein was inserted into an FPV vaccine strain licensed for use in chickens, Webster’s FPV, and the novel FPV vaccine strain FP9 by homologous recombination. The novel FP9 strain proved more potent as a vaccine for eliciting CD8+ T cell responses against the PbCS Ag. Sequential immunization with rFP9 and recombinant modified vaccinia virus Anakara (MVA) encoding the PbCS protein, administered by clinically acceptable routes, elicited potent CD8+ T cell responses against the PbCS protein. This immunization regimen elicited substantial protection against a stringent liver-stage challenge with P. berghei and was more immunogenic and protective than DNA/MVA prime/boost immunization. However, further improvement was not achieved by sequential (triple) immunization with a DNA vaccine, FP9, and MVA.
Assessing options for the small aortic root.

Valve selection for the small aortic root is a multifactorial process. Considerations include the effective orifice (EOA) of the implanted valve, annular size, body surface area (BSA), and valvular outflow tract of each patient. To decide if a valve is adequate for a patient, the valve EOA and patient BSA are used to calculate the indexed EOA (EOA/BSA). An indexed EOA <0.85 is associated with significant increases in mean systolic gradient with increase in cardiac output. The gradient remains low when indexed EOA is >0.85, leading to improved left ventricular mass reduction and decreased long-term risk of arrhythmias, congestive heart failure, and death. Biologic valves are usually used in patients aged over 65 years. Stented biologic valves tend to have a low EOA for their size. A 21-mm pericardial valve has an indexed EOA of 0.81 when implanted in a 1.6-m, 58-kg woman, and 0.69 in a 1.7-m, 72-kg man. Stentless valves (xenograft and homograft) have excellent EOAs and consequently very low gradients with good ventricular mass reduction. This allows for insertion of a larger valve, and results in more normal opening and flow dynamics. Hence, the best approach in over 65-year-old aortic valve patients when using a biologic valve is a stentless subcoronary implant. If this is not possible for anatomic reasons, a stented valve with an indexed EOA >0.85 is the best alternative. An option is root replacement with a xenograft or homograft, but the operative risk is significantly increased. The decision in younger patients (aged <65 years) is more complex. In-vivo EOAs for mechanical valves vary greatly; the St. Jude HP and Regent valves have consistently excellent EOAs. Recent results with the St. Jude Regent valve show gradients and left ventricular mass reduction close to those for stentless biologic valves. In a small aortic annulus, the decision must be made to use a more efficient valve (e.g. the Regent) or a biologic stentless valve, to perform annular enlargement (increasing surgical risk), or to tilt the stented valve to be supra-annular in the non-coronary cusp. The subvalvular outflow tract should not be ignored. Septal hypertrophy is not uncommon, and may increase the gradient across the outflow tract just below the valve. Finally, suture techniques (e.g. pledgetted versus interrupted simple sutures) can affect the long-term gradient. Pledgetted sutures can draw tissue underneath the valve and reduce the EOA. In conclusion, multiple factors must be evaluated when deciding which valve to use as a replacement in the small aortic root. These include patient age, lifestyle, pregnancy status, and drug compliance, as well as the indexed EOA of available prosthetic valves and the surgical procedure required for implant.
Does Phonological Change Play a Role in the Recognition of Derived Forms across Modalities?

This study investigates the way in which phonological change during derivation influences the access of complex words in the on-line performance of English-speaking subjects during word recognition. Three visual lexical decision experiments were administered (cross-modal priming, visual priming and simple). Overall, the results showed that the forms which were subject to phonological change during derivation were always recognized significantly slower than those without phonological alterations. The results confirm the role of phonological change in accessing derived words. They also have important implications for a theory of lexical representation.
A systematic review of the global prevalence of low back pain.

OBJECTIVE To perform a systematic review of the global prevalence of low back pain, and to examine the influence that case definition, prevalence period, and other variables have on prevalence. METHODS We conducted a new systematic review of the global prevalence of low back pain that included general population studies published between 1980 and 2009. A total of 165 studies from 54 countries were identified. Of these, 64% had been published since the last comparable review. RESULTS Low back pain was shown to be a major problem throughout the world, with the highest prevalence among female individuals and those aged 40-80 years. After adjusting for methodologic variation, the mean ± SEM point prevalence was estimated to be 11.9 ± 2.0%, and the 1-month prevalence was estimated to be 23.2 ± 2.9%. CONCLUSION As the population ages, the global number of individuals with low back pain is likely to increase substantially over the coming decades. Investigators are encouraged to adopt recent recommendations for a standard definition of low back pain and to consult a recently developed tool for assessing the risk of bias of prevalence studies.
A Generalized Knowledge Representation Architecture for Intelligent Tutoring System

An intelligent tutoring system (ITS) is a system that provides direct customized instruction or feedback to students without the intervention of human beings. Most of the research in ITS has been in evaluation, restructuring of the learning objects, and personalization of the learning object navigation path. With the explosion of content on the World Wide Web(WWW), the scope of application of Data Mining to E-Learning applications has increased tremendously. In this work, we identify a set of applications which go one step ahead from ITS and use the WWW to aid the learning process of the “learning object content”. Each application has a high level of coupling with the knowledge representation model, which models the resources stored in the Digital Library. This domain model must be complete and accurate otherwise the learning system will not perform effectively. This research presents the architecture for simplifying and automating the process of creating the domain model for an intelligent e-learning system. In this work we present an algorithm to create a knowledge representation of educational resources using the World Wide Web. We outline the advantages and limitations of this general architecture, and describe its implementation in Intinno – a developing Intelligent Learning Management System. The work is implemented for intinno, an intelligent web based learning content management system. The Intinno system aims to circumvent certain drawbacks of existing learning management systems in terms of scarcity of content, lack of intelligent search and context sensitive personalization. The system is deployed at http://www.intinno. com Table of
[Factorial structure of the executive functions in young university students].

INTRODUCTION Several studies have proposed a multiple dimensional theoretical model for executive function. OBJECTIVE To identify the factor structure of the executive function in a sample of young university students of different modalities of learning in their careers. METHODS 100 participants of both sexes, age 16 to-21-year old and normal Full Scale IQ were selected in a randomized and representative approach from private universities of Medellin Colombia. They were student of verbal, visuospatial and mathematical careers. A executive function assessment battery were applied, which included: Wisconsin Card Sorting Test (WCST), Trail Making Test (TMT) A and B, verbal fluency test (FAS) by phonologic and semantic guides, and Stroop test. RESULTS A structure of four factor was found, which explained 74.9% of variance. Factors were: 1. Organization and flexibility, which explained 26.6% of variance; 2. Processing speed, 19.7%; 3. Inhibitory control, 15.1%; and 4. Verbal fluency 13.4%. CONCLUSION A multiple factor structure of the executive function in young university students was demonstrated.
Prevalence of mood, anxiety, and substance-abuse disorders for older Americans in the national comorbidity survey-replication.

OBJECTIVES Current information on the prevalence of psychiatric disorders among older adults in the United States is lacking. Prevalence of anxiety, mood, and substance disorders was examined by age (18-44, 45-64, 65-74, and 75 years and older) and sex. Covariates of disorders for older adults (65 years and older) were explored. DESIGN Cross-sectional epidemiologic study, using data from the National Comorbidity Survey-Replication. SETTING Community-based epidemiologic survey. PARTICIPANTS Representative national sample of community-dwelling adults in the United States. MEASUREMENTS The World Health Organization Composite International Diagnostic Interview was used to assess Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition psychiatric disorders. RESULTS Prevalence of 12-month and lifetime mood, anxiety, and substance-use disorders was lower for older adults (65 years and older) than younger age groups: 2.6% for mood disorder, 7.0% for anxiety disorder, 0 for any substance-use disorder, and 8.5% for any of these disorders (for any disorder, 18-44 years = 27.6%, 45-64 years = 22.4%). Among older adults, presence of a 12-month anxiety disorder was associated with female sex, lower education, being unmarried, and three or more chronic conditions. Presence of a 12-month mood disorder was associated with disability. Similar patterns were noted for lifetime disorders (any disorder: 18-44 years = 46.4%, 45-64 years = 43.7%, and 65 years and older = 20.9%). CONCLUSIONS This study documents the continued pattern of lower rates of formal diagnoses for elders. These rates likely underestimate the burden of late-life psychiatric disorders, given the potential for underdiagnosis, clinical significance of subthreshold symptoms, and lack of representation from high-risk older adults (e.g., medically ill, long-term care residents).
Valvular Heart Disease: A Primer for the Clinical Pharmacist

Valvular heart disease is a commonly encountered clinical condition that is not taught in most undergraduate and graduate pharmacy programs, leaving the practicing pharmacist without basic knowledge to expand on and subsequently apply to direct patient care. Unlike other areas of cardiology in which thousands of patients are recruited in many well‐designed randomized clinical trials, data assessing treatments for valvular heart disease are limited and often consist of retrospective case series or observations. Our goal is to provide a basic overview of chronic valvular heart disease, with emphasis on describing the common conditions requiring surgery and the available options, as well as common pharmacologic therapies used in this patient population. Anomalies in valves can be broadly classified as stenosis and regurgitation. Depending on the valve and the type of anomaly, the impact on the cardiovascular system will vary. Understanding the hemodynamic consequences of aortic stenosis, aortic regurgitation, mitral stenosis, and mitral regurgitation is imperative to effectively counsel patients surrounding disease progression and self‐monitoring, use of vasodilators, and prophylaxis for endocarditis and rheumatic fever. Further, patient characteristics factored into the choice of implanting either a bioprosthetic (tissue) or prosthetic (metal) valve encompass patient choice, life expectancy, and willingness or ability to accept lifelong anticoagulation therapy. The evolution of metal valves has resulted in newer generations under clinical study that have more laminar flow (minimizing interaction with blood products) and improved pyrolytic carbon (minimizing infection and interaction with blood products). Although antithrombotic therapy with warfarin is now mandatory in North America for all patients receiving metal valves, research is ongoing to assess the need with the most recent generation of valves.
Trust Transference from Online to Mobile Shopping - Academic and Practical Consideration

Although mobile computing is getting popular but shopping with mobile devices does not follow the trend. The fundamental reason is the transaction security. Following Model of Argument by Toulmin and Persuasion Principles by Cialdini, we proposed the Trust Transference Facilitator (TTF) to convince users that the mobile shopping is secure. Similar mechanism has been proven to be effective and this study provides evidence that such mechanism can be transferred to the mobile environment. We found that authority+contrast+scarcity mechanism was the most effective way to convince users that the transaction is secure.
Modern Trends in Total Knee Arthroplasty

Knee arthritis is a common disease that causes pain and disability. Non-surgical treatments include NSAIDs, lowimpact exercise, physical therapy, ambulatory assist devices and intra-articular injections. When these treatments fail to alleviate pain and restore knee function, such as in severe cases of knee osteoarthritis, total knee arthroplasty (TKA) may be necessary. Modern TKA has evolved significantly from its first incarnation and success rates are high. Various types of implants have the potential to allow more knee flexion and improved range of motion, but current studies show high-flexion devices do not conclusively improve function. Computer-assisted navigation during surgery allows greater accuracy in alignment, but may not ultimately improve survival rate or function. Complications during TKA surgery can involve infection, pain, and blood loss; intra-articular tranexamic acid can be used to decrease blood loss, while wound drains may increase blood loss. TKA patients under regional anesthesia appear to have fewer complications than patients under general endotracheal anesthesia.
Moving Neighborhoods and Health Research Forward: Using Geographic Methods to Examine the Role of Spatial Scale in Neighborhood Effects on Health

A rich history of research documents the effects of neighborhood-level socioeconomic status (SES) conditions on health outcomes. Recent criticism of the neighborhoods and health literature, however, has stressed several conceptual and methodological challenges not adequately addressed in previous research. Critics suggest that early work on neighborhoods and health gave little thought to the spatial scale at which SES factors influence a specific health outcome. This article discusses the concept of neighborhoods and health, reviews recent criticisms of existing work, and provides a case study that exemplifies how geographic methods can address one such criticism. Using data on birth defects in North Carolina, the case study examines the relation of SES to orofacial clefts (cleft lip and cleft palate) at different spatial scales. The Brown–Forsythe test is used to select optimal neighborhood size. Results are evaluated using logistic regression models to examine the relationship between SES measures and orofacial clefts, controlling for individual-level risk factors. Results indicate modest associations between neighborhood-level measures of poverty and cleft palate but no associations with cleft lip with or without cleft palate.
Otogenic Meningitis Caused by the Pneumococci that had Acquired Resistance to Cephalosporins

Meningitis is one of the most serious complications of middle ear infection. Before the antibiotic era, most patients died, but the use of antibiotics has substantially decreased the mortality rate.1 Recovery depends on early diagnosis and treatment with appropriate antibiotics. Today, increasing resistance to antimicrobial agents has been reported among many pathogens including Streptococcus pneumoniae (S pneumoniae). 2,3 Infection is once again becoming one of the most serious medical problems. In this case report, we describe a rare case of otogenic meningitis ensuing after acute otitis media, caused by cephalosporin-resistant S pneumoniae. There have been no reported cases of meningitis as a complication of adult acute otitis with bacteria that had gained resistance to cephalosporins. The detection of the antigen was useful in the early identification of the responsible organism, and polymerase chain reactions (PCR) facilitated selection of appropriate antibiotics.