Miracle-dz/UniFAR-FTUs huggingface dataset:
Alzheimer and Helicobacter Pylori; Should We Fight and Kill or Save H. Pylori!! We Should Save H. Pylori

This review study aimed at assessment of the bacterium Helicobacter pylori whether it is guilty, not guilty or innocent towards the brain and Alzheimer disease (AD). AD is a chronic age-related degenerative disease characterized by loss of cognitive and memory functions. A genetic theory was suggested while the amyloid hypothesis is the most accepted. There are many medical pathologies that could contribute to Alzheimer such as diabetes, hypertension and dyslipidemia. Other factors like toxic elements, air pollution and nutrition are also under consideration. A lot of controversy entails the influence of systemic ammonia and the endothelial-liberated nitric oxide (NO) on the pathogenesis of the amyloid disease and in turn on the onset and progress of Alzheimer disease. Elevated levels of ammonia is toxic and is associated with progress of the amyloid disease and dementia symptoms. Excess NO is involved in nitro-oxidative stress sequels resulting in endothelial and neuronal degeneration. Meanwhile, the normal level of ammonia could help to maintain the neuro-protective function of NO via its endothelial liberation due to the effect of shear stress. Accordingly, the normal-behavior H. pylori strains in the stomach could be biologic and healthy towards Alzheimer and the brain while the colonic H. pylori strains could be considered pathologic and toxic to the brain and dementia symptoms. AD remains a disease without real cure or prevention because of permanent degeneration of some areas of the brain; therefore, attempts to delay the onset and symptoms of Alzheimer constitute intelligent and practical strategies. Eradication of colonic H. pylori strains via natural colon clear might be the most effective measure among these strategies as it eliminates the main pathologic source with its greater toxic influence in addition to amelioration of other factors contributing to AD such as diabetes, hypertension and dyslipidemia. On conclusion, H. pylori-produced ammonia in accordance could constitute at the mean time a cure and a poison towards Alzheimer while the natural existence of the bacterium H. pylori is biologic and protective; hence, it should be saved not killed.
Company Management’s and Auditor’s Reporting on Going Concern: Discussion of the Current International Regulatory Framework

In this study, we discuss if the current (international) regulatory framework regarding accounting and auditing provides an adequate basis for both company management and the auditor to report (accurately and informatively) on going concern.Overall findings indicate that from a theoretical perspective the changes made in the design of the framework since the last global economic crisis contribute to more accurate and informative reporting on going concern. This starts with an increased focus on substantiated reporting on long-term value creation and continuity in the U.K. and Dutch corporate governance codes. Furthermore, the current Dutch and U.S. accounting standards increasingly pay attention to reporting on going concern. Also several changes in the Dutch, international and (partly) U.S. auditing standards could have a positive impact, such as the requirement to state the responsibilities of both company management and the auditor in each auditor’s report, and the introduction of key audit matters offering the possibility to report on going concern risks and the audit procedures performed.There is, however, still room for improvement. It seems that various standard setters have determined their own route and pace, which may have kept them from implementing more progressive proposals such as a conclusion and a statement on going concern in each auditor’s report. As a result, the exception-based reporting model is still largely retained. Further progress can be made by implementing a so-called holistic approach to ensure that the responsibilities of company management and the auditor are aligned, and by striving for more international convergence.
HISTOLOGICAL STUDIES OF PANCREATIC B - CELLS OF STREPTOZOTOCIN - INDUCED DIABETIC WISTAR RATS TREATED WITH METHANOLIC EXTRACT OF SPHENOCENTRUM JOLLYANUM

Diabetes mellitus is characterized by hyperglycaemia and destruction in the microarchitecture of the β - cells of the pancreatic islets of Langerhans. The search for drugs with low cost, more potential and with less adverse effects is continuous. This study investigated the effects of methanolic extract of Sphenocentrum jollyanum on hyperglycemia and the morphological changes on pancreatic β - cells in streptozotocin - induced diabetic rats and compared the extract efficacy with glibenclamide, a known antidiabetic drug. Twenty four adult Wistar rats randomly divided into four groups were used. Gro up A was the control, diabetes mellitus was induced in groups B, C and D by a singl e intraperitoneal injection of streptozotocin (80mg/kg body weight) dissolved in 0.1 M citrate buffer. Group B diabetic rats were untreated while groups C and D received extracts of S. jollyanum (200mg/kg) and glibenclamide (5mg/kg) once daily for two week s respectively. The result showed a significant fall in blood glucose level with the extract and glibenclamide administration . Histological examination showed recovery of β - cells of the S. jollyanum and glibenclamide treated rats when compared with the dia betic group. There was no significant difference between the effects of the crude extract and the reference drug, glibenclamide.
Features of foreign policy birds: Israeli prime ministers as hawks and doves

Scholars and policymakers have long used the shorthand of hawks and doves to characterize leader personalities that correspond to a particular political inclination, whereby hawks are considered right-wing and more aggressive in foreign policy, and doves are left-wing and more peaceful. This article posits that a sound discussion of who hawks and doves in foreign policy are requires an engagement with research on political leadership. It promises a less superficial understanding of the dichotomy of hawks and doves, and uses leadership trait analysis to explore hawkish and dovish leaders’ qualities. The article profiles Israel’s prime ministers since the end of the Cold War, where in a high security environment, these words are most often used to describe its domestic and foreign matters and its cooperative and conflictual actions. This article’s findings encourage an unpacking of these commonly used shorthand labels with political leadership approaches. They are also useful to highlight, most notably, the significance of complexity and distrust in understanding hawkish and dovish leaders. Hawks think simpler and are more doubtful of others than doves, this article finds. Future research, the article suggests, will benefit from looking deeper than simple, dichotomous use of this analogy, and exploring ways to operationalize individual-level measurements of hawks and doves in foreign policy.
PENGEMBANGAN METODE MULTICRITERIA COLLABORATIVE FILTERING PADA SISTEM REKOMENDASI DOKUMEN

The main problem faced by the collaborative filtering-based recommender systems is the prediction accuracy and precision of recommendation. This research focuses on developing an algorithm of the prediction of ratings and the diversity exploration on a multicriteria collaborative filtering-based document recommender system. The development aims at improving the prediction accuracy and the precision of recommendations. The approaches used to improve the prediction accuracy are multirating matrix decomposition, multidimensional distance-based user similarity, the calculation of individual criteria weights, and the rating prediction for the overall criteria by using a combination approach, while the approach used to improve the precision of recommendation was to apply the concept of content-based and criteria-based diversity. Result of the research was the model of the document recommender system based on multicriteria collaborative filtering with characteristics as follows : (1) the rating prediction for the four individual criteria of documents used the pure algorithm of collaborative filtering, (2) rating prediction for the overall criteria used a combination algorithm, (3) the measurement of user similarity with a cosine approach and the concept of multidimensional distance, (4) the accommodation of diversity in the generation of recommendations. The testing of model was done on three conditions determined based on the number of users and documents, i.e., 50x100, 100x200 and 200x400 with variation in matrix sparsity rate of 10%, 20 %, 30 %, 40 %, 50 % and 60 %. Metric used to measure the prediction accuracy was the Mean Absolute Error (MAE), while the rate of the precision of recommendation was measured by using a percentage of Top-N. Based on the results of testing, it can be concluded that the multicriteria collaborative filtering method developed had much better performance than multicriteria collaborative filtering deceloped by previous researchers, which was characterized by the increasingly smaller values of MAE and a greater percentage of recommendation Top-N. The best performance was achieved by the model of Multicriteria Collaborative Filtering system that used multidimensional distance-based similarity. The application of the concept of document diversity on the generation of recommendation could contribute significantly to the increase of the precision of recommendation.
A critical framework for interrogating the United Nations Sustainable Development Goals 2030 Agenda in tourism

Abstract Research in the area of sustainable tourism continues to grow, however a lack of understanding regarding necessary action inhibits progress. McCloskey’s (2015) critique regarding the failure of the MDGs, as a direct result of a lack of critical consciousness, and understanding of the structural contexts of poverty and under-development, provided the impetus for our work. McCloskey (2015) signals the important role of education in fostering transitions to sustainability. As such, we have applied our critical lens to the 2030 United Nations Sustainable Development Goals. Our paper offers tools for critically thinking through the potential for the SDGs to help shape the tourism industry for more sustainable, equitable, and just futures. We positioned six themes to serve as a conceptual framework for interrogating the SDG agenda in tourism; arising from our considerations of both reformist and radical pathways to sustainable transitions in tourism: critical tourism scholarship, gender in the sustainable development agenda, engaging with Indigenous perspectives and other paradigms, degrowth and the circular economy, governance and planning, and ethical consumption. We address these core themes as essential platforms to critique the SDGs in the context of sustainable tourism development, and highlight the cutting edge research carried out by our contributors in this special issue.
An evaluation of feature selection methods and their application to computer security

The growing concern over the security of computer installations has led to the recent development of numerous intrusion detection systems. All of these systems rely on features of user and system behaviour to determine the likelihood of an attack. The choice of these features is somewhat arbitrary and is based solely on the opinion of an expert. This work surveys the existing field of feature selection in an attempt to discover efficient algorithms, both search procedures and eval\]ation functions, which select effective features for intrusion detection systems. In addition, a new search algorithm, random generation plus sequential selection, is presented and compared· to existing algorithms. Experiments show that random generation plus sequential selection, backward sequential selection, and beam search are the best search procedures to use in feature selection for intrusion detection systems. The experiments also showed that error rate evaluation functions are far superior to other methods of . evaluating feature subsets . A final and surprising result is that backward sequential selection, although examining only a small portion of the search space, always found small feature subsets· of high . predictive ability and is clearly the best overall search algorithm.
CFO appointment and debt-equity choice

Purpose There is some evidence that firms appoint internal candidates to exploit their unique firm specific knowledge and that the type of appointments may have signaling value to the market. However, these studies are limited to chief executive officer appointments whereas other top executives could also play an important role in corporate decision making. The purpose of this paper is to focus on the chief financial officer (CFO) appointments and firm’s debt-equity choice. Design/methodology/approach The authors employ a multiple regression framework. To control for potential endogeneity, the authors use an instrumental variable approach with both two-stage least squares and generalized method of moments estimators. Findings The authors find that firms with internal CFO hires issue more equity than firms that hire from the external labor market. The authors also find that internal CFOs significantly reduce information asymmetry (IA), which may lower market risk and the cost of financing through equity issues. Furthermore, consistent with the value maximizing role of reduced IA the authors find that this effect is concentrated in value firms. In firms with higher IA this preference for equity by the internal CFO may be weaker as even internal CFOs will prefer debt financing for its disciplining role and to reduce IA. A subsample analysis with growth firms shows this diminishing impact on the financing choice of an internal CFO. Originality/value This study provides important information about the influence the CFO has on a firm’s capital structure decisions.
In Other Words: A Coursebook on Translation

1. Introduction 2. Equivalence at Word Level 3. Equivalence Above Word Level 4. Grammatical Equivalence 5. Textual Equivalence: Thematic and Information Structures 6. Textual Equivalence: Cohesion 7. Pragmatic Equivalence 8. Beyond Equivalence: Ethics and Morality
CONFIABILIDADE DE EXAMES FÍSICOS PARA IDENTIFICAÇÃO DE DESEQUILÍBRIOS MUSCULARES NA REGIÃO LOMBOPÉLVICA

Testes para identificacao de desequilibrios musculares na regiao lombopelvica tem sido descritos na literatura. Estes testes sao descritos como sendo relacionados a estabilidade da coluna lombar, pelve e quadril. Entretanto, nao existem dados referentes a confiabilidade das medidas obtidas destes testes. O objetivo deste estudo foi determinar a confiabilidade inter e intra examinadores das medidas obtidas de quatro testes de desequilibrio muscular: musculos gluteo maximo x isquiotibiais e gluteo maximo x paravertebrais no movimento de extensao de quadril; gluteos maximo e medio x tensor da fascia lata no movimento de abducao de quadril; abdominais e flexores de quadril no movimento de flexao de quadril. Os testes foram aplicados por dois examinadores e um total de 29 individuos foram avaliados. Os dois examinadores aplicaram os testes em todos os participantes, com o reteste realizado apos intervalo de uma semana. A confiabilidade inter e intra-examinadores do julgamento da existencia de desequilibrio muscular em cada individuo, nos quatro testes realizados, foi determinada pelo coeficiente Kappa. Os coeficientes Kappa obtidos para as confiabilidades inter e intra-examinadores variaram de 0,457 a 1,00 para os quatro testes. Esses achados sugerem que a confiabilidade das medidas obtidas com os testes de desequilibrio muscular, descritos neste trabalho, variou de moderada a excelente. O fator que pode ter dificultado a obtencao de uma maior confiabilidade em alguns testes foi a palpacao de estruturas osseas necessaria para a sua realizacao. Os resultados deste estudo suportam a utilizacao clinica destes testes, desde que associados a outros exames no processo de avaliacao.
Deterministic end-to-end delay analysis in an avionics network

Avionics Full DupleX Switched Ethernet is a deterministic communication protocol for distributed embedded real-time applications over asynchronous channels. It is a promising technique that can replace the existing avionics data buses, such as ARINC429 and MIL-STD-1553B. One of the key challenges for deploying and maintaining Avionics Full DupleX Switched Ethernet is to determine the end-to-end transmission delay in such a network. This article aims at handling this challenge effectively applying a completely theoretical analysis. An analytical method based on the network calculus theory is presented in detail to calculate the end-to-end transmission delay in an Avionics Full DupleX Switched Ethernet network, which consists of many interconnect nodes with different scheduling disciplines. Further, this approach is improved by taking into account the effects of source node initial jitter and first in, first out optimization. Additionally, a Matlab/TrueTime simulation platform is constructed to verify the effectiveness of the method. Simulation results show that switches with advanced scheduling algorithms, i.e. static priority scheduling, can significantly improve the delay performance in a multi-hop network.
Two-Phase Collaborative Filtering Algorithm Based on Co-Clustering

This paper proposes a two-phase rating predicting framework that fuses co-clustering and non-negative matrix factorization method. First, it uses a novel co-clustering method (BlockClust) to divide the raw rating matrix into clusters much smaller than the original matrix. Then it employs weighted non-negative matrix factorization algorithm to predict the unknown ratings. In virtue of co-clustering preprocessing, this method achieves a higher predicting accuracy and efficiency on these low-dimensional and homogeneous sub-matrices. Moreover, it proposes three update schemes for the corresponding update scenarios in recommender systems. Finally, the proposed method is implemented together with seven types of related CF (collaborative filtering) methods. The comparisons show the efficiency of the proposed method and its potential in large real-time recommender systems.
Green by Choice: Is Becoming a Vegetarian a Green Statement?

The awareness of the environmental issues has made people to feel guilty about their past choices and to help minimize their negative impact they have decided to live a life based on sustainability. Living a sustainable life means, among other, to protect the environment. Therefore, people turned their usual consumption into a green way. The purpose of this thesis was to illustrate how two type of vegetarianism, flexitarians which are those people who on rare occasions consume meat but in generally they follow a plant based diet and actual vegetarians, could be integrated into a bigger group called green consumers. Although these two concepts are completely different, some similarities between them exist. Regarding their overall behavior, there is a connection between the choice of a vegetarian diet with the impact on the environment of personal overall consume and the perceived impact on the ecosystem of alimentary consume with the overall consume.
Summary of Non-rigid 3D Shape Data Retrieval and Description

Non-rigid 3D shape retrieval and descriptors has become an active and important research topic in contentbased 3D object. The aim of this paper is to compare and synthesize the performance of methods for non-rigid 3D shape retrieval and descriptors. This paper reviews the application of non-rigid three-dimensional shape data retrieval and description and obtains more detailed and valuable information on non-rigid three-dimensional shape data.
OPTIMALISASI KONDISI TERMAL DAN PEMBANGKITAN ENERGI PADA ATAP PHOTOVOLTAIC TERINTEGRASI DI DAERAH TROPIS LEMBAB

Atap photovoltaic (pv) terintegrasi pada bangunan merupakan salah satu cara memperoleh energi listrik. Meskipun di satu sisi energi listrik ini didapatkan secara cuma-cuma, di sisi lain radiasi matahari dapat memanaskan interior dan modul pv itu sendiri. Pemanasan interior akan menurunkan kualitas termal sedangkan pemanasan modul pv menurunkan daya listrik yang dihasilkan. Untuk mendapatkan kondisi optimum baik dari segi termal dan pembangkitan energi dalam konteks atap pv terintegrasi, peran ventilasi dan insulasi di ruang atap dalam menghambat laju pemanasan modul pv dan interior akan dikaji dan dieksplorasi dalam penelitian ini. Metoda penelitian gabungan, eksperimen dan simulasi, digunakan untuk memberikan penjelasan teoritis tentang perilaku panas di atap, ruang atap dan interior, perolehan energi listrik, kualitas termal interior serta untuk melakukan optimalisasi. Pada aspek termal, eksperimen digunakan untuk merumuskan peran ventilasi, insulasi kapasitif dan reflektif. Simulasi dengan perangkat lunak digunakan untuk mendapatkan tipe ventilasi dan insulasi ruang atap terbaik. Simulasi membantu memberikan penjelasan perilaku termalnya. Pada aspek pembangkitan energi, eksperimen digunakan untuk mendapatkan karakter modul pv sedangkan simulasi digunakan untuk mendapatkan besarnya insolasi pada bidang miring. Rumah tumbuh yang dikembangkan oleh pemerintah digunakan sebagai obyek eksperimen dalam penelitian ini. Dalam konteks aplikasi atap pv terintegrasi, hasil penelitian menunjukkan peran penting aliran konveksi dan radiasi di ruang atap dalam memanaskan interior. Ventilasi dan insulasi tipe “Y-terbalik” pada ruang atap adalah suatu model insulasi konveksi dan sistem ventilasi yang efektif dalam menghambat laju pemanasan interior dan modul pv. Kombinasi ventilasi dan insulasi tipe “Y-terbalik” pada ruang atap tipe pelana mampu mendekatkan kinerja termal dan pembangkitan daya listrik dengan kondisi optimal yang diharapkan, khususnya untuk aplikasi atap pv terintegrasi di daerah tropis lembab.
"Das sehen wir auch den Rädern ab": some thoughts on M. Vosteen's "Unter die Räder gekommen"

L'auteur de cette reflexion, prenant pour point de depart l'article de Markus VOSTEEN Unter die Rader gekommen paru en 1996 dans le volume 7 de la serie Archaologische Berichte, defend sa propre position sur l'etude de l'evolution des cultures prehistoriques en Europe et sur l'emergence des villes. Il reconnait la qualite de la recherche allemande fondee sur une analyse des relations culturelles a grande echelle et l'oppose a la recherche anglo-saxonne processuelle et a son approche localisee des problemes.
Computer Business Simulation Design: Novelty & Complexity Issues

Developing a business simulation is a time consuming, costly and potentially risky task. And, the risk of time and cost overrun is associated with the novelty and complexity of the simulation. This paper suggests the aspects of simulation novelty and complexity that are the sources of design risk and explores these in the context of a range of actual simulation designs so that designers can take action when forecasting costs, the development schedule and starting the design and development work. The areas of design novelty and difficulty are described and discussed in the context of five representative simulations. Following this the impacts on actual design difficulty and complexity are discussed and analyzed for the simulations. Finally, a design time model is proposed that empirically links model size with duration and novelty and design time with model size. In conclusion, the paper suggests that design time can be forecast from simulation duration provided the forecast is adjusted to take into account simulation novelty.