Miracle-dz/UniFAR-FTUs huggingface dataset:
Mental Illness in Hotel Residents

"The Hotel Study: Multimorhidity in a Community Sample Living in Marginal Housing" by Vila-Rodriguez and colleagues is published in this issue (1). The study is a survey of 293 men and women who were living alone in substandard hotels in poor Vancouver neighborhoods. Over half these people were psychotic and half had neurological illnesses, often traumatic brain injury. Over 95% abused substances. They are forgotten people, often homeless, who rarely come to medical attention untu they die. The article's senior author is William Honer, chair of the University of Vancouver Department of Psychiatry. His department, the Canadian health funding agencies, and the Portland Hotel Society are to be commended for reaching out to hotel residents. When I was in high school, my family owned such a hotel in St. Louis and I worked there. Indeed, alcoholism, brain injury, psychosis, and social isolation afflicted these tenants. Our mother told us their stories and taught us to treat them with the respect that their previous lives deserved, not with disdain over their afQicted condition. December was diffictilt. We put up a tree in the lobby, which everyone admired, but as the holiday week came closer, sadness overcame them. Our attorney, one of the most prominent in the city in his day, drank more heavily. His law firm could not stop him from drinking, but in a month they would detoxify him once again because the judge demanded his appearance in a pending litigation. They would drop him at our hotel after the hearing, stiU dressed in a new three-piece suit, and he would pavm his clothing to resume drinking. One morning we found him singing with several similar men, dovmcast and drunk, but stiU using the remnants they remembered of holiday songs to cheer themselves. I could not comprehend then his life or his illness, and after a career in psychiatry I am not sure that I have come any closer. But I understand that there are lessons to be learned from such lives.
Effect of water on the strength and microstructure of Carrara marble axially compressed at high temperature

In this study, we aimed to (i) answer the question if water affects the strength of marble deforming at high temperature and (ii) establish criteria that allow assessment of the role of water in microstructure development in marble. Samples of Carrara marble were axially compressed at temperatures ranging 600–1000 8C and strain rate w10 s, with or without addition of 0.4–2.1 wt% water. Water-added samples were found to be slightly weaker than dry samples. Microstructurally, all samples showed grain flattening and twinning at 600 8C and dynamic recrystallization dominated by grain boundary migration at higher temperature. Grain boundaries in wet samples showed isolated or semi-continuous remnants of fluid pockets. The average grain roundness R and fractal dimension D relating grain diameter d and grain perimeter P (Pfd) for wet recrystallized samples were systematically lower than for dry samples. At 600 8C, high pore fluid pressure probably enhanced dilatation of wet samples and helped grain boundary sliding (GBS), thereby lowering the strength. At higher temperature, fluid-enhanced grain boundary migration served as a recovery process, reducing the contribution of GBS to creep. Overall, water has little effect on strength and microstructure of marble experimentally deformed at high temperature. q 2005 Elsevier Ltd. All rights reserved.
Preclinical Strategies Tested for Neuroprotective Gene Transfer in Stroke

Accepted, March 4, 2004. NEUROSURGEONS, WORKING AS surgical scientists, can have a prominent role in developing and implementing genetic and cellular therapies for cerebral ischemia. The rapid emergence of both genetic and cellular therapies for neural regeneration warrants a careful analysis before implementation of human studies to understand the pitfalls and promises of this strategy. In this article, we review the topic of genetic and cellular therapy for stroke to provide a foundation for practicing neurosurgeons and clinical scientists who may become involved in this type of work. In Part 1, we review preclinical approaches with gene transfer, such as 1) improved energy delivery, 2) reduction of intracellular calcium availability, 3) abrogation of effects of reactive oxygen species, 4) reduction of proinflammatory cytokine signaling, 5) inhibition of apoptosis mediators, and 6) restorative gene therapy, that are paving the way to develop new strategies to treat cerebral infarction. In Part 2, we discuss the results of studies that address the possibility of using cellular therapies for stroke in animal models and in human trials by reviewing 1) the basics of stem cell biology, 2) exogenous and 3) and endogenous cell sources for therapy, and 4) clinical considerations in cell therapy applications. These emerging technologies based on the advancements made in recent years in the fields of genetics, therapeutic cloning, neuroscience, stem cell biology, and gene therapy provide significant potential for new therapies for stroke.
Polyunsaturated fatty acids in M. longissimus thoracis of fattening bulls fed silage of grass or maize

The polyunsaturated fatty acid (PUFA) content of M. longissimus thoracis was determined in Hereford, Limousine and Charolais fattening bulls fed concentrate and maize or grass silage as the basie feed for 7 months. The PUFA n-3 content was higher in Charolaise bulls than in other breeds, and was significantly higher in animals fed on grass than on maize silage. The ratio of PUFA n-6/n-3 was the most advantageous in Hereford bulls.
AGROBACTERIUM-MEDIATED GENETIC TRANSFORMATION AND REGENERATION FROM LEAF EXPLANTS OF SOLANUM THORVUM (SWARTZ) A MEDICINALLY IMPORTANT PLANT.

* Ugandhar T 1 , Odelu G 2 , Parvathi. D 3 , Anitha Devi U 4 and Venkateshwarlu M 5 . 1. Department of Botany, SRR Govt. Arts & Science College Karimnagar – 505001. 2. Department of Botany, Govt. Degree & P.G. College, Jammikunta, 505122. 3. Department of Botany, Govt. Degree & P.G. College Narsampet506132. 4. Department of Botany, Govt. Degree & P.G. College for Women Karimnagar505001. 5. Department of Botany, University College Kakatiya University Warangal – 506009. Manuscript Info Abstract . Manuscript History
Role of the UPS in myocardial ischaemia

The ubiquitin-proteasome system (UPS) plays a central role in protein degradation and regulates a variety of critical cellular processes. During recent years, the cardiac UPS has become increasingly recognized as a key regulator of cardiac function under both physiological and pathological conditions. Numerous studies have demonstrated that altered UPS function is involved in the pathogenesis of cardiac disease including myocardial ischaemia or infarction. The expression and activity of the E3 ubiquitin ligases, which confer substrate specificity in the UPS pathway, affect the apoptosis and severity of disease in myocardial ischaemia and reperfusion. Although impaired proteasome function is commonly associated with myocardial ischaemic injury, recent evidence also supports a cardioprotective role for proteasome inhibitors in myocardial ischaemia. We will review these studies and data, discuss controversies regarding the UPS alterations and use of proteasome inhibitors in myocardial ischaemia, and attempt to identify strategies that may enhance their clinical application.
The impact of the global financial crisis: What does this tell us about state capacity and political incentives to respond to shocks and manage risks? Literature review. Part 3: Globalisation and State Capacity

The distribution of the effects of the recent global financial crisis, as well as similar events in the past, reveal the extent of interconnectedness that has come to define the global economic system. As Newell (2002:5) describes, ‘While it is important to recall that many rural livelihoods in more remote areas of the world are not obviously and directly touched by changes within the global political economy, we should note the new forms of vulnerability that affect the rural poor as markets open up, and the shocks that reach distant suppliers when markets crash and financial crises unfold. ’ In this context, consideration of the changes in a state’s capacity to respond to such economic shocks that have accompanied this greater degree of interconnection is critical.
Pulsar Signal Characteristic Frequency Identification And Phase Estimation Base On FFT

To meet the detection of pulsars with low SNR, this paper presents a pulse signal recognition algorithm based on FFT. The new method could reduce the accumulation of time domain compared with the traditional method and could complete the detecting within a very short period of time First combined with the characteristics of pulsar signals ,make a theoretical description, for characteristic frequency identification method Second ,after fft ,by looking at the peak of a specific frequency ,find the characteristic frequency ,use it to estimate pulsar phase change in time domain . Third, Give the CRB(Cramer-Rao performance limit ) of characteristic frequency identification method. Use Mento-Carlo simulation for the simulation of pulsar PSRJ0007+7303. Simulation results show statistical results compared to the CRB in the same order of magnitude. Characteristic frequency identification method could achieve effective detection. The result shows Characteristic frequency identification method is an effective way for pulsar Identification and the evaluation of phase change which is directly related to the TOA parameters evaluation. Keywords--pulsar; fft; phase evaluation ;CRB; MentoCarlo
Movement and direction of movement of a simulated prey affect the success rate in barn owl Tyto alba attack

116.The present study was aimed at testing a novel idea, that rather than maximizing theirdistance from a predator during close-distance encounters, prey species are better offmoving directly or diagonally toward the predator in order to increase the relative speedand confine the attack to a single available clashing point. We used two tamed barnowls Tyto alba to measure the rate of attack success in relation to the direction of preymovement. A dead mouse or chick was used to simulate the prey, pulled to variousdirections by means of a transparent string during the owl’s attack. Both owls showed ahigh success rate in catching stationary compared with moving food items (90% and21%, respectively). Success was higher when the prey moved directly away, rather thantowards the owls (50% and 18%, respectively). Strikingly, these owls had 0% success incatching food items that were pulled sideways. This failure to catch prey that movesideways may reflect constraints in postural head movements in aerial raptors thatcannot move the eyes but rather move the entire head in tracking prey. So far there isno evidence that defensive behavior in terrestrial prey species takes advantage of theabove escape directions to lower rates of predator success. However, birds seem toadjust their defensive tactics in the vertical domain by taking-off at a steep angle, thusmoving diagonally toward the direction of an approaching aerial predator. Thesepreliminary findings warrant further studies in barn owls and other predators, in bothfield and laboratory settings, to uncover fine predator head movements during hunting,the corresponding defensive behavior of the prey, and the adaptive significance of thesebehaviors.D. Eilam (correspondence) and E. Shifferman, Department of Zoology, Tel-AvivUniversity, Ramat-Aviv 69 978, Israel. E-mail: eilam@post.tau. ac.il
Word Order In Paraguayan Guaraní1

This paper explores constraints on clausal word order in Paraguayan Guaraní on the basis of a corpus of naturally occurring data. We find that grammatical function is a strong predictor of word order for direct objects, since they are almost exclusively realized postverbally, as well as for indirect objects, which all occur postverbally. The placement of subjects, however, depends on a variety of factors, in particular discourse status and the transitivity of the verb. We find only partial support for the claim that Paraguayan Guaraní has a basic subject-verb-object word order (e.g., Gregores and Suárez 1967), since there does not seem to be a basic position for subjects. We conclude by comparing constraints on word order in Paraguayan Guaraní to constraints reported for other Tupí-Guaraní languages.
Clinical Practice Guidelines EASL Clinical Practical Guidelines on the management of acute ( fulminant ) liver failure q European Association for the Study of the Liver ⇑ Summary

The term acute liver failure (ALF) is frequently applied as a generic expression to describe patients presenting with or developing an acute episode of liver dysfunction. In the context of hepatological practice, however, ALF refers to a highly specific and rare syndrome, characterised by an acute abnormality of liver blood tests in an individual without underlying chronic liver disease. The disease process is associated with development of a coagulopathy of liver aetiology, and clinically apparent altered level of consciousness due to hepatic encephalopathy. Several important measures are immediately necessary when the patient presents for medical attention. These, as well as additional clinical procedures will be the subject of these clinical practice guidelines. 2016 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
IMPACT OF ALTERNATIVE FACTORS ON USAGE OF TELCO-LED BRANCHLESS BANKING SERVICES:EMPIRICAL EVIDENCE FROM PAKISTAN

This study analyzes the impact of alternative factors on usage of branchless banking services among different mobile users in Pakistan. The sample used in this study is based on 850 questionnaires filled by different mobile subscribers at franchises, retail outlets and shops in most populated city of Pakistan (Karachi) during January, 2015- December, 2015. The dependent variable in the study is the branchless banking adoption, which is a binary variable. We used binomial logistic regression analysis method and included a set of explanatory variables to predict the branchless banking usage and non-usage. The study found perceived usefulness had a strong positive impact on branchless banking adoption, while having a bank account was found to have a strong negative impact. Salaried persons, low-income groups and less educated population segment are more attractive towards usage of branchless banking products. The study concludes that mobile operator based branchless banking services has huge potential to reach unbanked and untapped segment of the society in Pakistan.
Effect of different Phosphorus sources and methods of application on growth, nodulation and yield of soybean (Glycine max (L) Merr.)

h Abstract: Afield experiment was conducted in the Sudan for two seasons 2011and 2012 at Gezira Research Station Farm which is the biggest Agricultural Research Corporation (ARC) stations. The main objective of this experiment was to investigate the effect of different phosphorus sources and methods of application on nodulation, growth and yield of soybean. Three phosphorus sources (Triple superphosphate (TSP), NPK and Diammonium phosphate (DAP)) were used with two methods of application (broadcasting and bedding), in addition to control. Soybean variety SY1448-11 was fertilized with the above mentioned phosphorus fertilizers at the rate of 43kgP2O5/ha (1P). The treatments were assigned in RCBD with four replicates. The shoot dry weight, grain and straw yields of soybean were significantly increased in response to the application of different phosphorus sources. All phosphorus sources increased the soybean nodulation and strain effectiveness. DAP fertilizer gave the highest values in all parameters measured. The bedding method produced highest grain and straw yields. These results recommended the fertilization of soybean by DAP at the rate of 43kg P2O5/ha using the bedding method. Other alternative include TSP as a source and broadcasting as a method if the recommended choice is not at hand. Economic evaluation was conducted to rank the most effective phosphorus fertilizers and method of application to reach the most economic and profitable level . The highest MRR was obtained from DAP fertilizer and bedding method (2360%).
Ordered Trees: A Structure for the Mental Representation of Information

This paper reviews the ordered tree technique for deriving a structured mental representation, and discusses potential applications for infonnation science. The ordered tree clustering algorithm that we are developing provides an alternative to more traditional approaches of clustering based on similarity matrices. This algorithm is based on patterns of linear strings, typically free-recall orders, but potentially any material organized in a linear fashion. The technique has proven useful in representing ordered classifications, such as an alphabet or a numerical sequence, imbedded within a hierarchical semantic structure. Furthermore, the ordered tree technique, its corresponding data structures, and the data analysis procedures, can be generalized to include cross-classification used by human subjects and the classification of subjects themselves into categories such as experts and novices. discusses potential applications for infonnation science. The ordered tree clustering algorithm that we are developing provides an alternative to more traditional approaches of clustering based on similarity matrices. This algorithm is based on patterns of linear strings, typically free-recall orders, but potentially any material organized in a linear fashion. The technique has proven useful in representing ordered classifications, such as an alphabet or a numerical sequence, imbedded within a hierarchical semantic structure. Furthermore, the ordered tree technique, its corresponding data structures, and the data analysis procedures, can be generalized to include cross-classification used by human subjects and the classification of subjects themselves into categories such as experts and novices.
TIBTEC 1399 No . of Pages 2 Spotlight A Bioprinted Liver-ona-Chip for Drug Screening Applications

Motivation for Liver-on-a-Chip Platforms Pharmaceuticaldevelopment iscostly (e.g., $2.6 billion per drug that enters themarket, csdd.tufts.edu/news/complete_story/ pr_tufts_csdd_2014_cost_study) and inefficient (e.g., 94% of drugs fail in the clinical trial phases, www.fda.gov/ForPatients/ Approvals/Drugs/ucm405622.htm). This is partially due to inadequate screening in preclinical trials, which can be [11_TD $DIFF]remediated using 3D engineered tissue platforms. 3D engineered [ 1 2 _ T D $ D I F F ]tissues can [ 2 _ T D $ D I F F ] mimic the in vivo structure, function, and response to drugs of human tissues [13_TD$DIFF] more accurately than 2D models, leading to better in vitro efficacy and safety screening before human trials [1,2]. Bioprinting has shown promise in creating complex 3D cellular architectures for a wide range of applications [3–6]. Microfluidic systems have been explored as a promising platform for high-throughput assays offering the ability to precisely control the flow of fluid, [14_TD$DIFF]provide nutrients, oxygen, and growth factors, as well as [15_TD$DIFF]remove waste, and have been shown to facilitate[16_TD$DIFF] the creation of several organs-ona-chip including cardiac [7] and skeletal muscle [8][3_TD$DIFF] and cancer tissues [9,10].
Reproductive status of Tribolium castaneum (Coleoptera: Tenebrionidae) affects its response to infection by Steinernema feltiae (Rhabditida: Steinernematidae)

Gender-specific reproductive roles are important factors determining sexual dimorphism. Here, we investigate the effects of sex-based differences and reproductive status on the defence of Tribolium castaneum (Herbst, 1797) (Coleoptera: Tenebrionidae) against infection by Steinernema feltiae (Filipjev, 1934) (Rhabditida: Steinernematidae). Female and male beetles, either virgin or post-copulation, were exposed individually to nematodes. Individuals were then sampled every 12 h, dissected, and checked for the presence of nematodes; we also measured their phenoloxidase (PO) activity. Reproductive status affected resistance to nematodes and PO activity as infected virgin individuals had a higher PO activity and lower mortality than reproducing individuals, with no differences between sexes. Mortality also increased with time, while PO activity did not change. Parasite load was related to reproductive status and sex, with reproducing females with the highest parasite loads in all treatments, and virgin males with more nematodes than sexually active males. Our results indicate that the costs of reproduction impair the immunological system of T. castaneum similarly in both sexes. It is possible, however, that other components of the immunological system that we did not measure, such as lysozyme activity, are impaired by infection with S. feltiae in a sex-specific way.
66-71 Epidemiology

Moffatt is Professor of Nursing, Centre for Research and Implementation of Clinical Practice (CRICP), Thames Valley University, London, and Anne Williams is Cancer Nursing Research Fellow, School of Acute and Continuing Care Nursing, Napier University, Edinburgh Lymphoedema of the upper arm and related trunkal areas is a recognised consequence of treatment for breast cancer. Despite this, the evidence on the epidemiology of this secondary cause of lymphoedema remains poor. This article will review the evidence as it stands, and the prevalence/incidence and factors that predispose patients to develop lymphoedema following treatment for breast cancer.
MONDian predictions for Newtonian mass-to-light ratios for ultrafaint dSphs

Under Newtonian gravity total masses for dSph galaxies will scale as $M_{T} \propto R_{e} \sigma^{2}$, with $R_{e}$ the effective radius and $\sigma$ their velocity dispersion. When both of the above quantities are available, the resulting masses are compared to observed stellar luminosities to derive Newtonian mass to light ratios, given a physically motivated proportionality constant in the above expression. For local dSphs and the growing sample of ultrafaint such systems, the above results in the largest mass to light ratios of any galactic systems known, with values in the hundreds and even thousands being common. The standard interpretation is for a dominant presence of an as yet undetected dark matter component. If however, reality is closer to a MONDian theory at the extremely low accelerations relevant to such systems, $\sigma$ will scale with { stellar mass} $M_{*}^{1/4}$. This yields an expression for the mass to light ratio which will be obtained under Newtonian assumptions of $(M/L)_{N}=120 R_{e}(\Upsilon_{*}/L)^{1/2}$. Here we compare $(M/L)_{N}$ values from this expression to Newtonian inferences for this ratios for the actual $(R_{e}, \sigma, L)$ observed values for a sample of recently observed ultrafaint dSphs, obtaining good agreement. Then, for systems where no $\sigma$ values have been reported, we give predictions for the $(M/L)_{N}$ values which under a MONDian scheme are expected once kinematical observations become available. For the recently studied Dragonfly 44 { and Crater II systems}, reported $(M/L)_{N}$ values are also in good agreement with MONDian expectations.