Miracle-dz/UniFAR-FTUs huggingface dataset:
Task scheduling in cloud computing based on metaheuristic techniques: A review paper

Cloud computing delivers computing resources like software and hardware as a service to the users through a network. Due to the scale of the modern datacentres and their dynamic resources provisioning nature, we need efficient scheduling techniques to manage these resources. The main objective of scheduling is to assign tasks to adequate resources in order to achieve one or more optimization criteria. Scheduling is a challenging issue in the cloud environment, therefore many researchers have attempted to explore an optimal solution for task scheduling in the cloud environment. They have shown that traditional scheduling is not efficient in solving this problem and produce an optimal solution with polynomial time in the cloud environment. However, they introduced sub-optimal solutions within a short period of time. Meta-heuristic techniques have provided near-optimal or optimal solutions within an acceptable time for such problems. In this work, we have introduced the major concepts of resource scheduling and provided a comparative analysis of many task scheduling techniques based on different optimization criteria.
The Realm of Oncological Lung Surgery: From Past to Present and Future Perspectives

In this chapter, a historical overview as well as an overview of state of the art of the surgical techniques for the treatment of lung cancer is outlined. The chapter focuses on the introduction of open surgery, video-assisted thoracic surgery (VATS), uniportal VATS (UVATS), and robotic-assisted thoracic surgery (RATS) techniques for lung resections. A short introduction on upcoming techniques and modalities is given. The currently available tools as three-dimensional (3D) computed tomography (CT), virtual reality, and endo-bronchial surgery will be discussed. Based on the current development, this chapter attempts to delineate the horizon of oncological lung surgery. The information is generated not only from the available literature, but also from the experiences of surgeons and other physicians as well as co-workers involved in lung cancer treatment around the world. This chapter can be seen as a general introduction to several aspects of oncological lung surgery.
An evolution simulation framework for ecological structure of crowd networks

This paper aims to obtain optimal specialization mode and level for complex network or system structures. In the e-commerce system, this paper studies the changes of each transaction subject in the process of ecological structure based on the income level of each transaction subject. ,This paper aims to research the change of transaction efficiency evolution process of intermediaries. With the improvement of transaction efficiency, intermediaries interact with other transaction subjects at given modes in e-commerce systems. This paper analyzes the relationship between the factors of production and trade and explains the quantitative relationship between them in the form of mathematical modeling. An evolution simulation framework is established to elaborate the simulation process and method of crowd network in e-commerce ecosystem and then sets up the simulation experiment. ,During simulation processes, the changes of data are observed and analyzed to obtain the optimal evolution paths and specialization modes. Furthermore, this paper provides solid supports for the research of the quantitative analysis of ecological structure evolutions. ,Evolution simulation of ecological structure is first proposed in the topic of crowd network. It is with the aid of the concept of ecology, the theory and method, simulation of complex network structure and system structure. This paper analyses and researches the evolution process of optimal specialization modes and intelligent level of crowd networks with transaction efficiency changing. The ecological structure optimal evolution paths can be obtained by trend of simulations.
Oceanic heat transport towards the Getz Ice Shelf, Amundsen Sea

The highest rates of ice shelf melt in Antarctica are found in West Antarctica. This is mainly due to the presence of warm Circumpolar Deep Water on the continental shelf, where it may come in direct contact with the ice shelves. Two years of mooring data (UIB3: 20162018) from a trough (the UIB3-trough) leading up to one of the central ice shelf fronts of the Getz Ice Shelf, Western Amundsen Sea, are used to describe the local hydrography and currents, their variability and possible drivers of this variability. Relatively warm modified Circumpolar Deep Water is present throughout the mooring period (maximum temperature: 0.13◦C), but meltwater is not observed. The mean current at UIB3 is weak (0.03m/s), and is directed towards the ice shelf. We discuss the observed variability in heat content in relation to interannual effects of changes in ocean surface stress. To study mechanisms that may bring modified Circumpolar Deep Water to UIB3, we investigate the impact of the ocean surface stress on the Ekman pumping at the shelf break, and discuss its relative importance in relation to variability in the along-slope eastward undercurrent, and the strength of the Antarctic Slope Front. The heat transport is closely connected to the current towards the ice shelf at UIB3. This current, and the ocean surface stress, have significant correlation that shifts between positive and negative values, in periods that tend to follow the seasons. Having only two years of mooring data limits us from drawing conclusions on the seasonality in our results. The highest correlation of about 0.5, with ∼15h lag, is found between the along-slope current at UIB3, and the ocean surface stress from a region east of UIB3, at the location of the Amundsen Sea Polynya. The observed seasonal signal in the westwards coastal current may be of importance for this high correlation, since it passes through the polynya and continues past regions near UIB3. We estimate that the upper limit of ice melt caused by the heat transport in the UIB3-trough may contribute to roughly 0.6m/year of the total ice melt of the Getz Ice Shelf.
OP-HMGJ160147 3269..3283

Predicting response to endocrine therapy and survival in oestrogen receptor positive breast cancer is a significant clinical challenge and novel prognostic biomarkers are needed. Long-range regulators of gene expression are emerging as promising biomarkers and therapeutic targets for human diseases, so we have explored the potential of distal enhancer elements of non-coding RNAs in the prognostication of breast cancer survival. HOTAIR is a long non-coding RNA that is overexpressed, promotes metastasis and is predictive of decreased survival. Here, we describe a long-range transcriptional enhancer of the HOTAIR gene that binds several hormone receptors and associated transcription factors, interacts with the HOTAIR promoter and augments transcription. This enhancer is dependent on Forkhead-Box transcription factors and functionally interacts with a novel alternate HOTAIR promoter. HOTAIR expression is negatively regulated by oestrogen, positively regulated by FOXA1 and FOXM1, and is inversely correlated with oestrogen receptor and directly correlated with FOXM1 in breast tumours. The combination of HOTAIR and FOXM1 enables greater discrimination of endocrine therapy responders and non-responders in patients with oestrogen receptor positive breast cancer. Consistent with this, HOTAIR expression is increased in cell-line Received: March 8, 2016. Revised: June 5, 2016. Accepted: June 7, 2016 VC The Author 2016. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com 3269 Human Molecular Genetics, 2016, Vol. 25, No. 15 3269–3283 doi: 10.1093/hmg/ddw177 Advance Access Publication Date: 4 July 2016
Aliasing error of the exp$(\beta \sqrt{1-z^2})$ kernel in the nonuniform fast Fourier transform

The most popular algorithm for the nonuniform fast Fourier transform (NUFFT) uses the dilation of a kernel $\phi$ to spread (or interpolate) between given nonuniform points and a uniform upsampled grid, combined with an FFT and diagonal scaling (deconvolution) in frequency space. The high performance of the recent FINUFFT library is in part due to its use of a new ``exponential of semicircle'' kernel $\phi(z)=e^{\beta \sqrt{1-z^2}}$, for $z\in[-1,1]$, zero otherwise, whose Fourier transform $\hat\phi$ is unknown analytically. We place this kernel on a rigorous footing by proving an aliasing error estimate which bounds the error of the one-dimensional NUFFT of types 1 and 2 in exact arithmetic. Asymptotically in the kernel width measured in upsampled grid points, the error is shown to decrease with an exponential rate arbitrarily close to that of the popular Kaiser--Bessel kernel. This requires controlling a conditionally-convergent sum over the tails of $\hat\phi$, using steepest descent, other classical estimates on contour integrals, and a phased sinc sum. We also draw new connections between the above kernel, Kaiser--Bessel, and prolate spheroidal wavefunctions of order zero, which all appear to share an optimal exponential convergence rate.
Effect of the Sodium Silicate Modulus and Slag Content on Fresh and Hardened Properties of Alkali-Activated Fly Ash/Slag

This paper presents the results of an experimental study performed to investigate the effect of activator modulus (SiO2/Na2O) and slag addition on the fresh and hardened properties of alkali-activated fly ash/slag (AAFS) pastes. Four activator moduli (SiO2/Na2O), i.e., 0.0, 1.0, 1.5, and 2.0, and five slag-to-binder ratios, i.e., 0, 0.3, 0.5, 0.7, 1.0, were used to prepare AAFS mixtures. The setting time, flowability, heat evolution, compressive strength, microstructure, and reaction products of AAFS pastes were studied. The results showed that the activator modulus and slag content had a combined effect on the setting behavior and workability of AAFS mixtures. Both the activator modulus and slag content affected the types of reaction products formed in AAFS. The coexistence of N–A–S–H gel and C–A–S–H gel was identified in AAFS activated with high pH but low SiO2 content (low modulus). C–A–S–H gel had a higher space-filling ability than N–A–S–H gel. Thus, AAFS with higher slag content had a finer pore structure and higher heat release (degree of reaction), corresponding to a higher compressive strength. The dissolution of slag was more pronounced when NaOH (modulus of 0.0) was applied as the activator. The use of Na2SiO3 as activator significantly refined the pores in AAFS by incorporating soluble Si in the activator, while further increasing the modulus from 1.5 to 2.0 prohibited the reaction process of AAFS, resulting in a lower heat release, coarser pore structure, and reduced compressive strength. Therefore, in view of the strength and microstructure, the optimum modulus is 1.5.
Serotonin differentially affects morph-specific behavior in divergent populations of a horned beetle

Associations between animal weapons and corresponding aggressive behaviors are among the most characteristic features of species, yet at the same time their co-expression is itself often strongly dependent on context, such as male condition or population ecology. Yet the mechanisms that modulate associations between aggression, morphology, and biological context remain poorly understood. The biogenic amine serotonin has been shown to regulate a wide range of aggressive and morph-specific behaviors in diverse insect species. However, the extent to which serotonin may coordinate the expression of behavior with morphology across biological contexts remains unclear. In this study, we pharmacologically increased serotonin biosynthesis in males of the polyphenic beetle, Onthophagus taurus, and assessed how this manipulation affects both aggressive and non-aggressive behaviors in alternative fighter and sneaker morphs, as well as in males derived from two rapidly diverging populations characterized by disparate levels of competition for mates. We find (i) that enhancing serotonin biosynthesis increases most measures of aggressive behaviors, but influences only a subset of nonaggressive behaviors, (ii) that similar serotonin-mediated behavioral changes manifest in both morphs within populations more often than just a single morph, and (iii) that males derived from the two focal populations have diverged in their behavioral responsiveness to serotonin up-regulation. Collectively, our study suggests that serotonin signaling plays a critical role in the regulation of male behavior and its evolution, including in the context of rapid, short-term population divergence.
Phytochemical Screening of Leaf Extracts of Eleven selected Tropical Plants Species from Eastern and Southern Nigeria

The pyhtochemical constituents of butanol and acid leaf extracts of eleven (11) plant species from three different families (Annonaceae, Apocynaceae and Euphorbiaceae) obtained from various locations in eastern and southern Nigeria were made following standard techniques. Results obtained show that the leaf extracts contain alkaloids, flavonoids and saponins. This paper provides evidence that alcoholic and acid leaf extract of the selected plant species studied contains medicinally important metabolites that justifies their usage as traditional medicine for treatment of various ailments.Keywords: Tropical plants, Phytochemicals, Ethno-medicine, Extracts
Expression of ER, PR and HER 2 Receptor Status in Breast Carcinomas and its Correlation with Histopathological Grading

Introduction: Breast cancer is the most common cancer in women in developed countries. In India; it is second to cancer of cervix among women. Several histopathological features have prognostic significance in breast carcinoma which includes histologic subtype, grade, lymph node status, ER/PR status, Growth factors and its receptors, proliferation activity and DNA content, oncogenes and tumor suppressor genes. The Immunohistochemistry (IHC) classification provides both therapeutic and prognostic information. Aim and objectives: To assesses the ER/PR status and HER -2 status of breast carcinoma, to correlate the ER/PR and HER-2 receptors status with modified BloomRichardson histological grading, and clinico pathological parameters. Materials and methods: This study was undertaken over a period of 2 years from August 2013 to July 2015 in the Department of Pathology, Chalmeda Anand Rao Institute of Medical Sciences. Total of 75 cases of carcinoma breast in females diagnosed histopathologically, belonging to age group of 21-85 years were included in the study. Pingle Prathyusha, Radhika Mucharla, V. Srinivas Kumar, Geeta Voolapalli, Thota Ravinder. Expression of ER, PR and HER 2 Receptor Status in Breast Carcinomas and its Correlation with Histopathological Grading. IAIM, 2019; 6(7): 49-58. Page 50 Results: Histopathological grading was done according to Modified Bloom Richardson’s grading. 27(36%) cases were of grade II and 24(32%) cases each were of grade I and grade III. ER and PR were positive in 76% and 58.7% of tumors respectively. HER-2 over expression (score 2+ & 3+) was seen in 44% of tumors and was negative (0 or 1+) in 56% of tumors. Among the most common histologic subtype i.e., IDC (NOS), ER, PR and HER-2 were expressed in 75.36%, 60.86% and 44.92% respectively. Tumors with ER/PR-, HER2+ subtype were larger (>5cms), 1(1.3%) each medullary and apocrine carcinoma were positive for HER-2. None of the lobular, mucinous and papillary carcinoma expressed HER-2. Statistically significant values were noted for histologic grade immunohistochemical sub types, lympho vascular invasion and nuclear pleomorphism. Conclusion: In this study ER, PR and HER-2 receptors status correlates well with histopathological grading and other clinico-pathological parameters. These assays have the advantage of allowing only tumor cells to be assessed for receptor status. They can be conducted relatively inexpensively on routinely processed tissue sections with no need for specialized equipment.
CMAR_A_229022 145..150

The Department of Blood Transfusion, Zhengzhou University First Affiliated Hospital, Zhengzhou, People’s Republic of China Aim: To investigate the expression of barrier-to-autointegration factor 1 (BANF1) and its prognostic significance in triple-negative breast cancer (TNBC). Methods: BANF1 immunohistochemical detection was performed in 60 TNBC specimens and 30 normal control tissues. Real-time PCR was performed to assess the expression of BANF1 gene in TNBC tissues and their correlations with proliferation and metastasis. Kaplan-Meier survival analysis was used to assess the effect of BANF1 expression on the relapse-free survival (RFS) of TNBC patients. Univariable and multivariable Cox proportional hazards regression model analysis was used to confirm independent prognostic factors. Results: Expression of BANF1 in TNBC was significantly higher than that of the normal control group (p<0.001), and it was related to the status of lymph node metastasis and TNM staging (p<0.05), and not related to age and tumor size (p>0.05). BANF1 expression has a positive correlation with MKI67 and MTA1 expression (p<0.01). Univariable analysis showed that expression of BANF1, the status of lymph node metastasis and TNM stage were related to the relapse-free survival (RSF) of TNBC patients (p<0.001, p=0.001, p=0.013, respectively). Multivariable Cox regression indicated that the status of lymph node metastasis was an independent prognostic factor for TNBC patients (p<0.001). The survival curve suggested that the survival times for TNBC patients with high BANF1 expression have no difference compared with that for the low-expression patients (p>0.05). Conclusion: Expression of BANF1 may play a role in the occurrence and development of TNBC. Lymph node metastasis was the only independent prognostic factor predicts a poor prognosis.
Dynamic vs. static! Different visualisations to conceptualize parameters of quadratic functions

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Dynamic vs. static! Different visualisations to conceptualize parameters of quadratic functions Lisa Göbel, Bärbel Barzel
pharmacology , drug action and pharmacokinetics Part 4 : The pharmacokinetic processes of metabolism and elimination

This is the fourth and final instalment in a series of articles on the basics of pharmacology, drug action and pharmacokinetics, in which interactive explanations are used to illustrate the last two of the four basic pharmacokinetic processes, namely metabolism and elimination (i.e. the ‘M’ and ‘E’ of the “ADME” processes). This series uses excerpts and diagrams with permission from the 2nd edition of Pharmacology in Clinical Practice: Application Made Easy for Nurses and Allied Health Professionals, and is compiled and expanded upon by the author. Pharmacology in Clinical Practice 2nd e i ion
Stability of particles inside yield-stress fluid Poiseuille flows

The stability of neutrally and non-neutrally buoyant particles immersed in a plane Poiseuille flow of a yield-stress fluid (Bingham fluid) is addressed numerically. Particles being carried by the yield-stress fluid can behave in different ways: they might (i) migrate inside the yielded regions or (ii) be transported without any relative motion inside the unyielded region if the yield stress is large enough compared to the buoyancy stress and the other stresses acting on the particles. Knowing the static stability of particles inside a bath of quiescent yield-stress fluid (Chaparian & Frigaard, J. Fluid Mech., vol. 819, 2017, pp. 311–351), we analyse the latter behaviour when the yield-stress fluid Poiseuille flow is host to two-dimensional particles. Numerical experiments reveal that particles lose their stability (i.e. break the unyielded plug and sediment/migrate) with smaller buoyancy compared to the sedimentation inside a bath of quiescent yield-stress fluid, because of the inherent shear stress in the Poiseuille flow. The key parameter in interpreting the present results is the position of the particle relative to the position of the yield surface in the undisturbed flow (in the absence of any particle): the larger the portion of a particle located inside the undisturbed sheared regions, the more likely is the particle to be unstable. Yet, we find that the core unyielded plug can grow locally to some extent to contain the particles. This picture holds even for neutrally buoyant particles, although they are strictly stable when they are located wholly inside the undisturbed plug. We propose scalings for all cases.
Nutrient Movements through Ruminant Livestock Production Systems

Considerable attention has been paid to reducing nutrient emissions from ruminant livestock in the last few decades. This area will continue to attract considerable research in the future due to increasing farm sizes in some developed countries as well as the increasing demand for meat and dairy products, particularly in developing countries. This paper discusses the deposition and losses of carbon and nitrogen in soils and plants in grazed and harvested forage systems as well as utilization and losses of both nutrients by ruminants in both systems. The paper also outlines several soil, plant, and animal– focused strategies that can be used to reduce carbon and nitrogen losses from ruminant livestock systems. These strategies will become increasingly important due to the need to feed the growing population of the world while reducing environmental pollution from ruminant livestock systems.
The quality of life of patients with cerebral palsy versus the general population

Introduction: Cerebral palsy (CP) is the most common cause of motor disability among children. This disease, as a compound syndrome, affects the biological, psychological, and social functioning of a patient and has different degrees. Feedback from studies on the quality of life (QoL) of children with CP make it possible to improve the relationship between a child suffering from CP and the surrounding external environment. Obtained information about the patient’s frame of mind and the limitations caused by CP allow us to perceive the problems that children suffer and take actions aimed at solving them. Improving the QoL of children with CP becomes one of the main goals of therapeutic interaction – in parallel with the alleviation of disease symptoms. Aim of the study: To assess the QoL of patients with CP as compared to the general population. Material and methods: The study was conducted among 128 patients with CP. The reference group consisted of 130 healthy subjects. The study was of prospective nature, conducted using a diagnostic survey based on the Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core. Results: Healthy children are characterised by better overall QoL. They also achieved significantly higher scores in individual subscales (physical, emotional, social, school, and psycho-social functioning) excluding emotional functioning. Conclusions: There is a need to implement comprehensive therapy for children with CP that enables self-care, or assistance in everyday self-care and school activities. It also seems important to adapt the home and school environment in accordance with the needs of patients suffering from CP.