Miracle-dz/UniFAR-FTUs huggingface dataset:
Cytological and histopathological study on cutaneous round cell tumours in canines

Out of 65 cases of cutaneous tumours studied in canines, 14 were round cell tumours. The transmissible venereal tumour (TVT) constituted seven, mast cell tumours four, histiocytomas two and histiocytic sarcoma one. Cytologically, the tumours yielded high cellularity. The TVT had punctate vacuoles in the cytoplasm. Mast cell tumours showed cytoplasmic granules. Histiocytoma revealed multinucleated cells. The histopathological study confirmed the cytological diagnosis. Thus, cytology can be used as a rapid and inexpensive technique for diagnosis of neoplasms. An algorithm was developed for cytological diagnosis of different round cell tumours in canines.
Communication in medical care: Interaction between primary care physicians and patients

1. Introduction: analyzing interaction between doctors and patients in primary care encounters John Heritage and Douglas W. Maynard 2. Soliciting patients' presenting concerns Jeffrey Robinson 3. Accounting for the visit: giving reasons for seeking medical care John Heritage and Jeffrey Robinson 4. Realizing the illness: patients' narratives of symptom discovery Tim Halkowski 5. Explaining illness: patients' proposals and physicians' responses Virginia Gill and Douglas W. Maynard 6. Taking the history: questioning during comprehensive history taking Elizabeth Boyd and John Heritage 7. Body work: the collaborative production of the clinical object Christian Heath 8. Communicating and responding to diagnosis Anssi Perakyla 9. On diagnostic rationality: bad news, good news, and the symptom residue Douglas W. Maynard and Richard M. Frankel 10. Treatment decisions: negotiations between doctors and patients in acute care encounters Tanya Stivers 11. Prescriptions and prescribing: co-ordinating talk and text-based activities David Greatbach 12. Lifestyle discussions in medical interviews Marja-Leena Sorjonen, Liisa Raevaara, Markku Haakana, Tuukka Tammi and Anssi Perakyla 13. Co-ordinating closings in medical interviews: producing continuity of care Candace West 14. Mis-alignments in 'after-hours' calls to a British GP's practice: a study in telephone medicine Paul Drew.
Speech therapy and physiotherapy intervention in a woman after ischemic stroke

Objetivos: Relatar um caso em que houve intervencao conjunta entre fonoaudiologo e fisioterapeuta na reabilitacao de uma paciente com acidente vascular cerebral isquemico. Descricao do caso: Paciente de 48 anos de idade, sexo feminino, acometida por acidente vascular cerebral do tipo isquemico, ha sete meses. Apresentou-se com disartrofonia e alteracoes do sistema estomatognatico e sua funcionalidade, comprometimento sensorial, parestesia da mao direita, diminuicao da coordenacao motora grossa e fina em ambos os membros superiores, dificuldade na preensao palmar e fraqueza da musculatura intrinseca da mao direita, diminuicao da consciencia corporal e da propriocepcao. Foi submetida a 12 sessoes com a periodicidade de uma vez por semana de tratamento fonoterapico e fisioterapeutico. Apos as intervencoes a paciente apresentou aumento dos tempos maximos de fonacao; melhora da coordenacao pneumofonoarticulatoria, da qualidade vocal e do foco de ressonância vertical; adequacao e modulacao da loudness ; modulacao do pitch ; melhora da coordenacao motora grossa e fina, da sensibilidade tatil e dolorosa, da oposicao dos dedos, da preensao palmar, da consciencia corporal, da propriocepcao e da postura corporal global; e aumento da forca muscular dos membros superiores. Conclusoes: A intervencao interdisciplinar da fonoaudiologia e fisioterapia proporcionou beneficios a paciente acometida por acidente vascular cerebral isquemico, sendo que a mesma voltou a exercer sua atividade profissional e suas atividades de vida diaria com efetividade e melhorou a comunicacao com seus familiares.
La utilización del betafosfato tricálcico como biomaterial en implantología oral

Introduccion. El objetivo del presente estudio era mostrar los resultados del tratamiento con implantes dentales insertados en diversas situaciones clinicas utilizando un biomaterial de relleno oseo. Metodos. 43 pacientes con perdidas dentales fueron tratados con 171 implantes Microdent®. En todos los casos, como biomaterial para regeneracion osea se utilizo el beta-fosfato tricalcico KeraOs®. Los implantes fueron cargados despues de un periodo de cicatrizacion de 6 meSes. ,. Resultados. Los hallazgos clinicos indican una supervivencia y exito de los implantes del 98,8% . 2 implantes se perdieron durante el periodo de cicatrizacion. En e167 ,4% de los pacientes se realizo tecnica de elevacion sinusal, en el 18,6% de los pacientes se realizaron implantes postextraccion y en el 14%, los implantes fueron insertados en rebordes alveolares atroficos. Despues de un periodo de carga funcional de 12 meses, no ha habido complicaciones tardias. El 54% de las protesis realizadas fueron puentes fijos; el 28% coronas unitarias; el 14% rehabilitaciones completas fijas y e14% sobredentaduras. Conclusiones. Este estudio indica que el beta-fosfato tricalcico puede ser utilizado con exito como material de regeneracion osea en el tratamiento con implantes dentales.
Global Strategy

(" MUFG ") and its group companies (collectively, " the group "). These forward-looking statements are based on information currently available to the group and are stated here on the basis of the outlook at the time that this document was produced. In addition, in producing these statements certain assumptions (premises) have been utilized. These statements and assumptions (premises) are subjective and may prove to be incorrect and may not be realized in the future. Underlying such circumstances are a large number of risks and uncertainties. Please see other disclosure and public filings made or will be made by MUFG and the other companies comprising the group, including the latest kessantanshin, financial reports, Japanese securities reports and annual reports, for additional information regarding such risks and uncertainties. The group has no obligation or intent to update any forward-looking statements contained in this document In addition, information on companies and other entities outside the group that is recorded in this document has been obtained from publicly available information and other sources. The accuracy and appropriateness of that information has not been verified by the group and cannot be guaranteed The financial information used in this document was prepared in accordance with accounting standards generally accepted in Japan, or Japanese GAAP
Inverse Charge Constant On-time Control with Output Current Feedforward for Superimposed Pulse Power Supply

Pulsed power supply (PPS) has been widely used in various applications. Its output current is pulsed, while output voltage and input power are required to be stable. Therefore, power decoupling scheme and load current tracking ability would have a great impact to the performance of the PPS. To solve the contradiction between the volume and efficiency in conventional active and passive power decoupling schemes, a superimposed pulse power supply that can adjust the volume and efficiency is introduced in this paper, and to improve the load current tracking performance of the PPS, an inverse charge constant on-time control with output current feedforward (OCF-IQCOT) is introduced.
Variabilidad Genética de Colletotrichum gloeosporioides (Penz.) Penz. y Sacc. Aislado de Frutos de Papaya (Carica papaya L.) Mediante el Uso de Marcadores Moleculares RAPD

Colletotrichum gloeosporioides shows a highly morphologic, pathogenic, and genetic variability, which has been difficult to evaluate through traditional methodologies. During the last few years, molecular marker techniques have facilitated the genetic separation and characterization. In this work, the genetic diversity of 21 monosporic isolates of C. gloeosporioides from papaya fruit collected in the states of Veracruz, Chiapas, and Campeche, Mexico, was evaluated. The RAPD technique was used to characterize the genetic diversity of the fungus by extracting DNA from each isolate. Eighteeen 10-base oligonucleotide of random sequences were used to react with DNA from each isolate. One hundred and thirty four polimorphic bands were obtained; OPX-16 showed the least number of bands (4), while OPX-04 and OPM-20 showed 12, being the highest number of bands. A dendrogram showed two main groups of isolates (A and B) widely separated, with a 100% of association between groups. Group A contained isolates Ca2, Ca3, and Ca5, which showed completely different genetic characteristics in relation to the remainder of isolates in group B. In general, It was observed a tendency to group association, according to the place of
Acquired Lymphangioma Circumscriptum of the Penis Treated by Electrocoagulation

Lymphangioma circumscriptum (LC) is a vascular malformation resulting from a developmental anomaly of the superficial lymphatic system of the skin. It is benign albeit uncommon. LC less frequently occurs on the penis. LC may be either congenital or acquired. Acquired cases appear to develop most frequently after interventions in the area or underlying pathologies. It is often mistaken for genital warts or molluscum contagiosum. We report here about a case of LC misdiagnosed with genital warts for 15 years. A biopsy eventually provided histopathological evidence. Various treatments are available for LC including surgical excision (which is the gold standard), CO2 laser ablation, cryotherapy, flash lamp pulsed dye laser, and electrocoagulation therapy. For our patient, one session of electrocoagulation was performed under local anesthesia. This treatment allowed an almost complete regression of the lesion without recurrence after 3 years of follow-up. Electrocoagulation may be an efficient treatment for LC in locations that may be surgically challenging such as penis.
Implications of kappa-casein evolutionary diversity for the self-assembly and aggregation of casein micelles

Milk alpha-, beta- and kappa-casein proteins assemble into casein micelles in breast epithelial cells. The glycomacropeptide (GMP) tails of kappa-casein that extend from the surface of the micelle are key to assembly and aggregation. Aggregation is triggered by stomach pepsin cleavage of GMP from para-kappa-casein (PKC). While one casein micelle model emphasizes the importance of hydrophobic interactions, another focuses on polar residues. We performed an evolutionary analysis of kappa-casein primary sequence and predicted features that potentially impact on protein interactions. We noted more rapid change in the earlier period (166 to 60 Ma). Pepsin and plasmin cleavage sites were avoided in the GMP, which may partly explain its amino acid composition. Short tandem repeats have led to modest expansions of PKC, and to large GMP expansions, suggesting the GMP is less length constrained. Amino acid compositional constraints were assessed across species. Polarity and hydrophobicity properties were insufficient to explain differences between PKC and GMP. Among polar residues, threonine dominates the GMP, compared to serine, probably reflecting its preference for O-glycosylation over phosphorylation. Glutamine, enriched in the bovine PQ-rich region, is not positionally conserved in other species. Among hydrophobic residues, isoleucine is clearly preferred over leucine in the GMP, and patches of hydrophobicity are not markedly positionally conserved. PKC tyrosine and charged residues showed stronger conservation of position, suggesting a role for pi-interactions, seen in other structurally dynamic protein membraneless assemblies. Independent acquisitions of cysteines are consistent with a trend of increasing stabilization of multimers by covalent disulphide bonds, over evolutionary time. In conclusion, kappa-casein compositional and positional constraints appear to be influenced by modification preferences, protease evasion and protein–protein interactions.
Metastatic prostate cancer presenting as a retroperitoneal mass: a case report and review of literature

Abstract Prostate cancer (PCa) is the second most common cancer diagnosed in men globally, after lung cancer. Many patients with PCa are asymptomatic until the tumor has progressed. The prognosis of PCa mainly depends on the presence of metastatic spread. It usually metastasizes to the bone, lung, and liver. Retroperitoneum is an exceedingly rare site for metastatic PCa to occur. We describe a case of a 68-year-old male patient presented for left flank pain and lower limb edema. A retroperitoneal mass was identified on imagery. This mass was found to be due to metastatic prostate adenocarcinoma based on immunohistochemical studies. Knowledge of this atypical presentation of metastatic PCa will reduce the diagnostic delay and allow the appropriate timely treatment.
Ketosis-Prone Type 2 Diabetes: A Case Series

Ketosis-prone type 2 diabetes (“Flatbush diabetes”) carries features of both classical type 1 and type 2 diabetes and is highly prevalent in African populations. The disease, which is highly ketosis-prone, but neither chronically insulinopenic nor autoimmune, is discussed regarding pathogenesis, diagnosis and treatment from a patient case perspective.
Efficient Bitcoin Password-protected Wallet Scheme with Key-dependent Message Security

In Bitcoin ﬁnancial system, a user is required to generate a fresh key pair to sign a new transaction for protecting privacy. Therefore, a large volume of key pairs need to be stored in Bitcoin wallets. The password-protected wallet, however, is vulnerable to computer crash and ransomware attack. On the other hand, the password itself could be contained in the wallet which would result in the password information leakage by the so-called Key-Dependent Message (KDM). To address these two problems, we propose a new password-protected wallet scheme in this paper. Users can upload the encrypted backup ﬁles to the cloud. When the local wallet is lost or damaged, users can recover it via the backup ﬁles. To resist against the KDM attack, we use a KDM secure scheme to encrypt wallet ﬁles. We prove that our scheme is KDM-CCA secure and the semi-trust cloud server cannot get any information of the backup ﬁles. The simulation results show that our scheme is eﬃcient and practical.
Structural and Functional Changes in the Central Nervous System Following Cancer Therapy

Chemotherapy Induced Peripheral Neuropathy (CIPN) is known to im­ pact negatively on patients' quality of life. It has been reported that these patients tend to have sensitivity thresholds to stimuli, such as pain and tem­ perature, that are different from those of normal subjects. The effect of chemotherapeutic agents on the central nervous system (CNS) has been ob­ served; however, most of the mechanisms involved are not exactly understood. A quantitative investigation into the temperature sensitivity changes in the spinal cords and brains of chemotherapy patients would provide important information in understanding the side effects of this treatment modality. In the first part of the project, the temperature perceptional changes in terms of brain activation patterns of the chemotherapy patients with CIPN are studied using brain function MRI. In the second part of the project, the structural changes of the brain and spinal cord of chemotherapy patients with CIPN are studied using diffusion tensor imaging (DTI). High b-value (b = 1500 s/mm ) and low b-value (b=650 s/mm2 ) settings will be use during the spinal cord DTI scans. Due to the sample size limitation, no comparison between healthy vol­ unteers and CIPN patients can be done based on the existing temperature fMRI data. However, the developed temperature fMRI protocol shows good reliability in detecting temperature response. Based on the spinal cord DTI result using b = 1500 s/mm , decrease in FA value has been observed. The corresponding FA values of CIPN patient and healthy volunteers are 0.28±0.10 and 0.41±0.02 , respectively. ( t-test = 2.63 >2.447, p=0.05 level of signifi­
Attribution of Ghrelin to Cancer; Attempts to Unravel an Apparent Controversy

Ghrelin is an endogenous peptide hormone mainly produced in the stomach. It has been known to regulate energy homeostasis, stimulate secretion of growth hormone, and mediate many other physiologic effects. Various effects attributed to ghrelin contribute to many aspects of cancer development and progression. Accordingly, a large body of evidence has emerged about the association of ghrelin with several types of cancer in scales of cell-line, animal, and human studies. However, existing data are controversial. This controversy occurs in two main domains: one is the controversial results in local effects of ghrelin on different types of human cancer cell-lines; the second is the apparent disagreement in the results of in-vitro and clinical studies that investigated ghrelin association to one type of cancer. These inconsistencies have hampered the indications to consider ghrelin as a potential tumor biomarker or therapeutic agent in cancer patients. Previous studies have reviewed different parts of current literature about the ghrelin-cancer relationship. Although they have highlighted these controversial results in various ways, no specific recommendations have been given to address it. In this study, we comprehensively reviewed in-vitro, in-vivo, and clinical studies and attempted to use the following approaches to unravel the inconsistencies detected: (a) to distinguish local and systemic effects of ghrelin in interpreting its summary clinical role in each cancer; (b) scrutinizing factors that regulate local effects of ghrelin and could justify different effects of ghrelin on different cancer cell-lines. These approaches could have notable implications for future in-vitro and clinical studies.
Rational time investment during collective decision making in Temnothorax ants

The study of rational choice in humans and other animals typically focuses on decision outcomes, but rationality also applies to decision latencies, especially when time is scarce and valuable. For example, the smaller the difference in quality between two options, the faster a rational actor should decide between them. This is because the consequences of choosing the inferior option are less severe if the options are similar. Experiments have shown, however, that humans irrationally spend more time choosing between similar options. In this study, we assessed the rationality of time investment during nest-site choice by the rock ant, Temnothorax albipennis. Previous studies have shown that collective decision-making allows ant colonies to avoid certain irrational errors. Here we show that the same is true for time investment. Individual ants, like humans, irrationally took more time to complete an emigration when choosing between two similar nests than when choosing between two less similar nests. Whole colonies, by contrast, rationally made faster decisions when the options were more similar. We discuss the underlying mechanisms of decision-making in individuals and colonies and how they lead to irrational and rational time investment, respectively.
Interactive effects of foundation species on ecosystem functioning and stability in response to disturbance

A major challenge in ecology is to understand determinants of ecosystem functioning and stability in the face of disturbance. Some important species can strongly shape community structure and ecosystem functioning, but their impacts and interactions on ecosystem-level responses to disturbance are less well known. Shallow ponds provide a model system in which to study the effects of such species because some taxa mitigate transitions between alternative ecosystem states caused by eutrophication. We performed pond experiments to test how two foundation species (a macrophyte and a mussel) affected the biomass of planktonic primary producers and its stability in response to nutrient additions. Individually, each species reduced phytoplankton biomass and tended to increase rates of recovery from disturbance, but together the species reversed these effects, particularly with larger nutrient additions. This reversal was mediated by high cyanobacterial dominance of the community and a resulting loss of trait evenness. Effects of the foundation species on primary producer biomass were associated with effects on other ecosystem properties, including turbidity and dissolved oxygen. Our work highlights the important role of foundation species and their interactive effects in determining responses of ecosystem functioning to disturbance.
Rapidly expanding nuclear arsenals in Pakistan and India portend regional and global catastrophe

Severe global climate change and a record death toll could result from nuclear war between India and Pakistan in the next decade. Pakistan and India may have 400 to 500 nuclear weapons by 2025 with yields from tested 12- to 45-kt values to a few hundred kilotons. If India uses 100 strategic weapons to attack urban centers and Pakistan uses 150, fatalities could reach 50 to 125 million people, and nuclear-ignited fires could release 16 to 36 Tg of black carbon in smoke, depending on yield. The smoke will rise into the upper troposphere, be self-lofted into the stratosphere, and spread globally within weeks. Surface sunlight will decline by 20 to 35%, cooling the global surface by 2° to 5°C and reducing precipitation by 15 to 30%, with larger regional impacts. Recovery takes more than 10 years. Net primary productivity declines 15 to 30% on land and 5 to 15% in oceans threatening mass starvation and additional worldwide collateral fatalities.
A New Chi-square Distribution De-noising Method for Image Encryption

In order to protect the security of the image, it is necessary to encrypt image and process domain image. Therefore, this paper proposes a new encryption domain image processing algorithms, image is encrypted using a sub-block scrambling pixel location algorithm. Then the image is denoised. Considering a given noisy image, the selection of thresholds should signiﬁcantly affect the quality of the de-noising image. Although the state-of-the-art wavelet image de-noising methods perform better than other de-noising methods, they are not very eﬀective for de-noising with diﬀerent noise and with redundancy convergence time, sometimes. To mitigate the poor eﬀect of traditional de-noising methods, this paper proposes a new wavelet soft threshold based on the Chi-square distribution-Kernel method. The Chi-square distribution-Kernel (CSDK) model is constructed to ﬁnd the customized threshold that corresponds to the de-noised image. Then, the image receiver gets the de-crypted image using the key restored pixel location. Finally, experimental results illustrate that this computationally scalable algorithm achieves state-of-the-art de-noising performance. The encryption results are also better.