Miracle-dz/UniFAR-FTUs huggingface dataset:
Eosinophilic pancreatitis presenting as possible malignancy

Abstract Eosinophilic pancreatitis is a rare form of chronic pancreatitis that is often mistaken for malignancy due to nonspecific presenting symptoms and noncontributory auxiliary exams. This clinical case report highlights a unique presentation of chronic pancreatitis. A middle-aged man developed abdominal pain, and repeat imaging showed an interval increase in size of a known pancreatic lesion. A core biopsy showed benign pancreatic tissue with eosinophilic-rich inflammation; IgE levels were also elevated. The patient was started on a prednisone taper, and repeat computed tomography 3 months later showed a decreased size of the pancreatic lesion. Correct and timely diagnosis of eosinophilic pancreatitis may avoid invasive unnecessary surgical procedures and allow for earlier initiation of appropriate therapy.
Risk of migraine in iron deficiency anemia patients with or without iron supplementation usage: a nationwide database analysis

Material and methods All study subjects aged ≥20 years with newly diagnosed IDA in the Taiwan National Health Insurance Database during 2000–2012 were enrolled. We matched IDA and non-IDA subjects according to age and sex at a 1:2 ratio. Our primary outcome was diagnosis of migraine, and the patients were monitored until the end of 2013. A Cox proportional hazards regression model was used to evaluate the risk of migraine events in IDA.
Competition Restricts the Growth, Development, and Propagation of Carpinus tientaiensis: A Rare and Endangered Species in China

The protection and propagation of rare and endangered species are key to the preservation of their population development; however, due to the scarcity of individuals, the potential effects and status of rare and endangered species in the whole forest ecosystem are still poorly understood. Using data from a 60 × 140 m forest dynamic monitoring sample of the Carpinus tientaiensis (Betulaceae) species in Zhejiang of Southeast China. We assessed the population distribution and diameter at breast height (DBH) structure of the Carpinus tientaiensis species, which was a rare and endangered species, as well as intra- and interspecific correlation with other species. The results show that saplings (1 cm ≤ DBH < 5 cm) and juveniles (5 cm ≤ DBH < 10 cm) were more aggregated than larger individuals (DBH ≥ 20 cm) of Carpinus tientaiensis. The DBH size structure of all the trees shows an obvious inverted “J” distribution. With an increase in the DBH size category, the number of individuals gradually decreases. Due to the diffusion limitation, the spatial distribution patterns of all the tree individuals and roof geese in the sample land are increased at a small spatial scale, and as the spatial scale increases, the degree of aggregation decreases gradually. The relationship between different diameter stages of the population of Carpinus tientaiensis showed a consistent general trend. The spatial distribution of individuals with a large diameter on a small scale was significantly positively correlated (p < 0.001). With an increase in the scale, there was no significant correlation (p > 0.05) between individuals with a large diameter and individuals with a small diameter. There was no significant correlation (p > 0.05) between the population of Carpinus tientaiensis and other species in the sample, and the strong unidirectional competition of other species in the sample can be seen by the competition index. We found that interspecific competition restricts the growth and expansion of Carpinus tientaiensis, and it has adopted different ecological strategies to coexist with a population of common tree species occupying a similar living space.
APPLICATION METHOD OF DIGITAL CLASSIFICATION TO MAKE LAND RESOURCES MAP

The Lumajang Urban Area (BWP) is the center of government and the economy in Lumajang Regency. The growth and development of cities in BWP Lumajang every year results in significant land changes. Thus, a map of land resources in Lumajang BWP is needed to determine the level of land use in the area. This research was conducted to make the Lumajang BWP Land Resource Map of Lumajang Regency using Geographic Information Systems (GIS). This study uses data processing methods with Object-Based Classification (OBIA). The data used for this study are the results of the Pleiades 1-A High-Resolution Satellite Image (CSRT) segmentation in 2016. The data used as an initial reserve (asset) is the 2009 RBI map. The data used for resource utilization (liability) is the result segmentation of Pleiades 1-A HighResolution Satellite Imagery (CSRT) in 2016. In processing OBIA using scale, shape, and compactness parameters. In this study, it can be seen that the scale parameters have the greatest role in the formation of OBIA segmentation. The smaller the scale value is given results in more accurate segmentation. The results of this study are that at a higher level of accuracy is the method of image segmentation method of 89,041% and the land cover that has the largest decrease in area is irrigated rice fields and the largest increase is a plantation.
A Systematic Review and Meta-Analysis of the Role of Toll-Like Receptor 9 in Alzheimer’s Disease: The Protocol for a Systematic Review

Context: Alzheimer’s disease (AD) is a neurodegenerative disease affecting many people around the world. Recently, it has been reported that toll-like receptors (TLRs) play a role in AD; therefore, the present study aimed to systematically review the studies and to meta-analyze the role of toll-like receptor 9 (TLR9) in AD. Methods: Seven main electronic databases, including PubMed/MEDLINE, Web of Science, Embase, Scopus, CINAHL, Cochrane, and Google Scholar, will be considered with no language restrictions. Full texts of articles will be prepared by a determined search strategy. Studies including the assessment of TLR9 function in adults with AD, published before June 15 2020, will be considered. Hence, this protocol will be presented based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statements for protocols. The related results and data analyses will be provided in the final review. This paper plans the protocol for a systematic review identifying TLR9 up-regulation and down-regulation in adults with AD. Conclusions: The meta-analysis of TLR9 may subsequently provide attractive therapeutic tools for AD.
Effect of Natural and Chemical Colorant Supplementation on Performance, Egg-Quality Characteristics, Yolk Fatty-Acid Profile, and Blood Constituents in Laying Hens

Natural and chemical colorants are attracting a lot of attention as sustainable feed additives due to their effect on food color and because presentation matters to consumers. Color also is a major sensory factor that helps consumers determine food quality and its possible health benefits. For example, highly colored egg yolks can only come from healthy laying hens fed a well-balanced, nutrient-rich diet. Consumers associate an intense yolk color with healthy, nutrient-rich food. There is a growing market request for eggs with rich yolk coloring. The purpose of the current study was to evaluate the impact of natural (paprika) and chemical (carmoisine) colorant supplementation on the performance, egg-quality characteristics, yolk fatty-acid profile, and blood constituents in laying hens. A total of 240 Bovans laying hens were randomly distributed in a completely randomized design in four treatments according to four experimental diets: a control diet (without supplementation of any colorants), a control diet supplemented with 4 kg/ton paprika, a control diet supplemented with 150 g carmoisine/ton, and a control diet supplemented with a combination of 4 kg/ton paprika plus 150 g carmoisine/ton, fed from 42 to 54 weeks of age. Each treatment consisted of 10 replications with six hens. Dietary inclusion of paprika colorant improved (p < 0.05) the feed-conversion ratio and egg-production rate, while final body weight, weight change, feed intake, and egg weight and mass were not affected. The degrees of egg yolk and white were increased (p < 0.05) by the dietary supplements. Yolk color and shell thickness were enhanced (p < 0.05) by adding paprika and/or carmoisine colorants. Supplementation of the paprika colorant alone or in combination with carmoisine increased (p < 0.05) linolenic acid, oleic acid, and vitamin E concentrations in egg yolks. In contrast, egg yolk palmitic acid and liver malondialdehyde contents were decreased (p < 0.05). Paprika and carmoisine colorants and their combination improved (p < 0.05) blood lipid profile in treated hens. We concluded that the dietary supplementation of natural (paprika) colorants has an influential role in improving egg yolk color, production performance, and egg yolk fatty-acid profile in laying hens.
Treatment of drinking water for rural households using Moringa seed and solar disinfection

Rural populations in Tanzania use unsafe drinking water from unimproved water sources which are inadequately treated using plant seed powder. The effectiveness of defatted crude seed extract (dCSE) of Moringa oleifera along with water filtration and solar disinfection (SODIS) for rural household water treatment was investigated. The performance of dCSE in turbidity and bacteria reduction was evaluated in 20 L buckets using river water with varied turbidities. Coagulation– flocculation processes were conducted using different dosages of 5% (Weight/Volume) dCSE. Optimum dosage for maximum turbid removal was established after 2–6 h of settling time. Optimum dosages of dCSE were 20, 30 and 80 mL/20 L for water with a turbidity of 150, 450 and 1,000 NTU with turbidity removal efficiencies of 98, 99 and 99%, respectively. The filtration process was able to remove about 66% of suspended solids from pretreated water by dCSE after coagulation/ flocculation/sedimentation. SODIS of pretreated water in black painted and unpainted bottles removed 99 and 97.6%; 99.9 and 98.6% of total and fecal coliforms after 6 h of sunlight exposure, respectively. The pH and color of treated water were within Tanzania Standards. This study recommends dCSE, filtration and SODIS for use at household level for water treatment and storage using pots.
Fine‐scale soil heterogeneity at an urban site: implications for forest restoration

Soils within a forested park in New York City, NY, USA, were sampled to evaluate spatial variation in pH on a disturbed forest restoration site, and compare soil physicochemical parameters (pH, texture, moisture, organic matter [OM], plant available Mg, Ca, Mn, Al, Fe, K, Na, P, Cu, and Zn) between the restoration site and an intact forest. The divergence of soil parameters between sites suggests that forest clearing on the restoration site initiated the erosion of fine particles and altered soil chemistry. Within the restoration site, the spatial pattern, and correlation with base‐cations, suggests that localized impacts from the built environment drive fine‐scale pH variation with implications for nutrient availability and native plant establishment. The majority of our site was found to be unsuitable for native species adapted to acidic soils. However, sampling points spaced less than 10 m apart can capture the pH variation and allow for the identification of acidic soil patches.
ChikonEye: Open Source Software for Preventing Unauthorized Access to Electronic Devices and Information using Face Recognition

In this emerging era of technology, ensuring data security is a challenge to be provided for systems of different sizes and types. An open source software is presented to allow authorization to a device having sensitive work-related information. In an exemplification of this project, an unlocked device configured to capture images, analyze the images to see who and how many faces are looking at the device and automatically locks the device if detected faces is not recognized as authorized. The software is implemented using open source computer vision (OpenCV) library for image processing operation. The recognizer has been trained with 100 images of each authorized user to generate a dataset on which the system relies to recognize authorized users using openCV python bindings. Voila-Jones algorithm is used to detect faces in images using the built in camera of a system.
Car Following and Microscopic Traffic Simulation Under Distracted Driving

Microscopic simulation models have been widely used as tools to investigate the operation of traffic systems and different intelligent transportation systems applications. The fidelity of microscopic simulation tools depends on the driving behavior models that they implement. However, current models commonly do not consider human-related factors, such as distraction. The potential for distraction while driving has increased rapidly with the availability of smartphones and other connected and infotainment devices. Thus, an understanding of the impact of distraction on driving behavior is essential to improve the realism of microscopic traffic tools and support safety and other applications that are sensitive to it. This study focuses on car-following behavior in the context of distracting activities. The parameters of the well-known GM and intelligent driver models are estimated under various distraction scenarios using data collected with an experiment conducted in a driving simulator. The estimation results show that drivers are less sensitive to their leaders while talking on the phone and especially while texting. The estimated models are implemented in a microscopic traffic simulation model. The average speed, coefficient of variation of speed, acceleration noise and acceleration and deceleration time fractions were used as measures of performance indicating traffic flow and safety implications. The simulation results show deterioration of traffic flow with texting and to some extent talking on the phone: average speeds are lower and the coefficient of variation of speeds are higher. Further experimentation with varying fractions of texting drivers showed similar trends.
Current Promising Therapeutic Targets for Aspergillosis Treatment

Aspergillosis is a fungal disease caused by different species of Aspergillus. they live in soil,dust and decomposed material. Number of Aspergillus species found till now is about 300 and more are still to be identified. Only few Aspergillus species can cause human disease and the most common species for human infection is Aspergillus fumigatus, which is a ubiquitous airborne saprophytic fungus. Severity of the disease ranges from an allergic response to life-threatening generalized infection. They grow optimally at 37°C and can grow upto 50°C. The fungal conidia are being constantly inhaled by humans and animals everyday normally gets eliminated by innate immune mechanism. Due to increasing number of immunocompromised patients, severe and fatal Aspergillosis cases have augmented. Currently, available antifungal drug for the treatment of Aspergillosis act on these three molecular target are 14 alpha demethylase for Azoles, ergosterol for Polyene and β-1,3-glucan synthase for Echinocandin. These antifungal drug show high resistance problem and toxicity. So, it is high time to develop new drugs for treatment with reduced toxicity and drug resistant problem. Synthesis of essential amino acid is absent in human as they obtain it from their diet but fungi synthesis these amino acid. Thus, enzymes in this pathway acts as novel drug target. This article summarizes promising drug targets presents in different metabolic pathway of Aspergillus genome and discusses their molecular functions in detail. This review also list down the inhibitors of these novel target. We present a comprehensive review that will pave way for discovery and development of novel antifungals against these drug targets for Aspergillosis treatment.
Effects of the abolishment of London western charging zone on traffic flow and vehicle emissions

Abstract This paper applies the regression discontinuity method to evaluate the effects of the removal of London western charging zone (WCZ) scheme on the traffic flow characteristics and traffic-related emissions, based on the data of 525 road sections. First of all, continuity of the confounders is assessed. Results indicate that all the confounders are continuous at the cutoff. Then, the impacts of implementing and abolishing the WCZ scheme are investigated. Results indicate that the overall traffic volume is reduced by 31% after implementing the WCZ scheme. On the contrary, the overall traffic volume in the concerned area is increased by 26% after the abolishment. For the environmental effects, results indicate that the traffic-related NOX and CO2 emissions are reduced by 29% and 33% respectively after implementing the WCZ scheme and bounced back by 24% and 21% respectively after the abolishment. These imply that there are moderate residual effects for the removal of WCZ scheme on the traffic volume and traffic-related CO2 emission. However, the residual effect on the traffic-related NOx emission is marginal.
The words used commonly both in Turkish and in Georgian

Strong neighbor relations between Georgia and Turkey have allowed for many interactions to be intensely experienced and maintained in language and culture just as in many areas. The effective communication that both countries established with each other during the historical process has reflected on their vocabulary and enabled thousands of common words to take place in both languages. This interaction continuing between the two communities has become even stronger today and the demand to learn Turkish and Georgian has extremely increased. To this end, in this study it is aimed to determine the words used commonly in Turkish and Georgian in order to enable either Turkish learners or Georgian learners to be better motivated in language acquisition and take the researches for the field a step further. By means of document analysis method many sources were reviewed and thereby a lot of words used commonly in both languages were found. Besides, the study also comprises the changes in the Georgian dialect, which is used in the Adjarian region, an autonomous republic of Georgia, but not used in official Georgian and some field researches to determine this have also partly been done. Accordingly, thousands of common words are found between Turkish and Georgian, but most of these are of Adjarian dialect of Georgian. In this context, just as the dimensions of the reflection of differences such as language, culture, geography, etc. among the regions specific to Georgia on language are understood, the power of the relationship between Turkish and Georgia is also presented with this study.
CNN based efficient image classification system for smartphone device

In our work, we look to classify images that make their way into our smartphone devices through various social-media text-messaging platforms. We aim at classifying images into three broad categories: document-based images, quote-based images, and photographs. People, especially students, share many document-based images that include snapshots of essential emails, handwritten notes, articles, etc. Quote based images, consisting of birthday wishes, motivational messages, festival greetings, etc., are among the highly shared images on social media platforms. A significant share of images constitutes photographs of people, including group photographs, selfies, portraits, etc. We train various convolutional neural network (CNN) based models on our self-made dataset and compare their results to find our task’s optimum model.
MR-guided blood-brain barrier opening induced by rapid short-pulse ultrasound in non-human primates.

Background Opening the blood-brain barrier (BBB) with focused ultrasound and microbubbles (MBs) has potential use in non-invasive targeted therapy for central nervous system (CNS) diseases. Rapid short-pulse (RaSP) ultrasound with a microsecond sequence has been proposed as a minimally disruptive and efficient method for opening the BBB. This work aimed to test the feasibility and safety of BBB opening in a non-human primate model using combined RaSP ultrasound sequence and MBs. Methods The BBB of 2 rhesus macaques were opened with RaSP and the commonly used 10 millisecond long pulse (LP), combined with microbubble (SonoVueTM, 0.2 µL/g) injection in a bolus. The transducer's central frequency was 300 kHz, and the acoustic pressure was set to 0.56 MPa calibrated in water. The BBB opening procedure was guided and evaluated with contrast-enhanced magnetic resonance imaging. The relative signal enhancement was compared between RaSP and LP sonication. T2-weighted fast-spin echo (FSE) and T2*-weighted gradient echo (GRE) sequences were scanned to evaluate edema and micro-bleeding at the end of the procedure. Results The relative signal enhancement was significantly higher (P<0.01) in the focal area compared to a similar area of the opposite hemisphere at all time points after sonication in each monkey, indicating the successful opening of the BBB. The relative signal enhancement in RaSP reached more than 60% of that with LP in our experiment, while the energy deposition was only 6% of LP. No edema or hemorrhage was found on magnetic resonance images after RaSP. Conclusions Combined RaSP ultrasound and MBs for the BBB opening is a practical method in large animal models.
Effects of Salinity-Induced Chemical Reactions on Biotite Wettability Changes under Geologic CO2 Sequestration Conditions

The wettability of rocks and minerals significantly affects the safety and efficiency of energy-related subsurface operations. Salinity is an important controlling factor in terms of wettability but has received limited attention. We studied the effects of salinity-induced chemical reactions on biotite’s wettability changes under relevant subsurface conditions. Biotite was reacted at 95 °C and 102 atm of CO2 for 70 h in solutions with salinities of 0, 0.1, 0.5, and 1.0 M NaCl. Then, static and dynamic water contact angles on reacted biotite basal surfaces were measured using a captive drop method. As a result of enhanced biotite dissolution at higher salinities, increased roughness, more negatively charged surfaces, and higher densities of hydroxyl groups on the biotite surfaces made biotite basal surface more hydrophilic. These results provide new information about the interplay of chemical reactions and wettability alterations of minerals, providing a better understanding of CO2 transport in subsurface .
Changes Of The Dnieper-Dvina Region Business Environment

In December 2019, the Union State of Russia and Belarus celebrated 20 years. It is relevant to analyze the impact of the changed economic conditions due to interstate integration on border regions' business environment. The article presents the results of organizations' activities and individual entrepreneurs of the Russian-Belarusian border area, the change in which is indirectly related to the influence of the integration factor. For the analysis, the Smolensk, Vitebsk, and Mogilev regions (Dnepro-Dvinsky region) were selected - transit, near-capital, and border regions. The positive and negative aspects of the influence of these factors on the region's business environment are presented. The results obtained are based on interviews conducted from 2019 to 2020 and covered 90 entrepreneurs operating in the Dnipro-Dvinsky region. The article presents both generalized results of interviews and individual assessments of changes in the business environment. The authors describe the topical (in the opinion of entrepreneurs) characteristics of the business climate, barriers to their development, and entry into neighboring regions' markets. Regularities of parameters changes of the Dnieper-Dvinsky region business environment due to the implementation of the stages of integration between Russia and Belarus have been established. The research results will be used in the development of regional strategies for socio-economic and investment development and a strategy for the spatial development of the territories of the Union State.