Miracle-dz/UniFAR-FTUs huggingface dataset:
Ultrasonographic Features of Lower-Limb Joints in Gout

Objective This observational cross-sectional study evaluated the distribution of ultrasound (US) features of lower-limb joints and the risk factors of tophus in gout patients. Methods We examined 588 joints including the bilateral knee, ankle, and first metatarsophalangeal (MTP) joints in 98 gout patients by US between March to August in 2017. The distribution of double-contour (DC), tophus, aggregates, synovitis, effusion and erosion in different joint, course, and age groups were investigated by Cochran Q and χ2 test. The risk factors of tophus were analyzed using logistic regression method. Results Double-contour was most commonly observed in the knee (p = 0.005). Tophus, aggregates, synovitis, and erosion were mostly detected in the first MTP (p < 0.001, p = 0.01, p = 0.001, p < 0.001, respectively). The prevalence rates of DC, tophus, and erosion in patients with a longer course were significantly higher (p = 0.029, p = 0.002, p < 0.001, respectively). Older patients had more detectable tophus and erosion than younger patients (p = 0.028, p = 0.021). Patients of older age (odds ratio [OR], 3.83; 95% confidence interval [CI], 1.27–11.48), with frequent attacks (OR, 3.80; 95% CI, 1.10–13.15), and with longer course (OR, 6.52; 95% CI, 1.37–30.96) had higher risks of tophus. Conclusions Most signs were detected by US in the first MTP, except that DC was most commonly observed in the knees. Patients of older age with frequent attacks and longer course may experience higher risks for tophus. Comprehensive assessment of the lower limbs, particularly the knee and first MTP, can significantly help diagnosis.
Low power Optimum Design of BCD Adder in Reversible Logic

Reversible logic has captured significant attention in recent time as reducing power consumption by recovering bit loss from its unique input-output mapping. This paper presents a compact $n -$digit BCD adder where a low cost reversible ODU gate is proposed. Theoretical explanations certify the novelty of the proposed design. Comparing with previous works the proposed design shows significant improvement in all performance metrics compared to the best existing BCD adder, as an example, the proposed 512-bit reversible BCD adder improves 38.46%, 47.83%, 70.60% and 63.64% in terms of number of gates, garbage outputs, quantum cost and delay compared with the existing best design.
PV-HESS fed BLDC Driven Water Pumping System with PSO-based MPP Tracking Employing Zeta Converter

The increased importance of renewable sources in the field of automotive sector entails the use of solar photovoltaic (PV)-fed water pumping system driven by a brushless DC (BLDC) motor drive. To overcome the drawback associated with the conventional DC-DC converters, a zeta converter is employed to optimize the power processing. The maximum power is extracted from the solar array by controlling the duty cycle of zeta converter through particle swam optimization (PSO) based maximum power point tracking (MPPT) algorithm. To mitigate the PV output variation, hybrid energy storage system (HESS) is integrated to the PV system which inturn maintains the constant voltage at the input of BLDC motor drive. A robust power management algorithm is employed for proper control of PV-HESS system. The overall MPPT with power management control facilitates the zeta converter to meet smooth performance of the water pumping system. The performance of the proposed controller is demonstrated using MATLAB/Simulink for variation in atmospheric condition and Xilinx system generator control platform interfaced with Zynq ZC-702 FPGA kit.
SPR Gas Sensor Using Bimetallic Structure Based on Gold Grating-Aluminum Film

We propose a bimetallic Au-Al based SPR sensor. FWHM of SPR curve of conventional Au grating based sensor could be reduced by using the proposed bimetallic structure and thereby improving the resolution. Sensitivity of the proposed sensor is 191°/RIU with an FWHM of 0.26°.
The Design and Implementation of Script Authoring Assistant System of Film and Television Big Data

Big data is increasingly becoming a hot research topic, applied to all walks of life. And the film and television big data makes big data science and film and television industry blend together, making far-reaching impact on the film and television works of creation, dissemination, acceptance and other aspects. With the hit of different types of films and TV plays, the screenwriter directing industry has become a lot of people dream career, they eager to show talent in this area. The significance of this paper is to use the online writing mode of the script to draw the figure of character relationship. It can clearly grasp the characters in the script by visualization, and make the decision support of the characters and balance the role relation to ensure the scriptwriter’s layout is reasonable. Based on the current situation of script creation and the actual needs of users, so that different levels of users can freely create character relationship map, and give the role of quantitative analysis of the results, so as to achieve the purpose of supporting the creation.
Image processing for multitemporal SAR images

In 1996, the French research group ISIS* proposed a research initiative in the field of radar imaging. One purpose aims to study specificities of multitemporal SAR (synthetic Aperture Radar) images. This paper presents some results of research undertaken in the multitemporal workgroup. In this paper two different kinds of SAR multitemporal data have been distinguished: temporal sequences of spatial images and images containing temporal information like interferograms. To each of them, correspond different types of image processing. The multitemporal information may be used either to enhance static information (multitemporal filtering) or to study temporal evolution (change detection, temporal tracking of structures). In this paper, two different methods of quality restoration are proposed to enhance amplitude data using sequences of SAR images. Then a model for detecting and tracking environmental non-rigid structures (like the coastal line) is explained. Lastly, a segmentation method for phasimetric effects on interferograms is described.
Homer's Iliad - A Social Network Analytic Approach

In this paper we provide some insights in Homer's Iliad from the perspective of social network analysis. We use the original text and other public available data to create a social network (i.e. a graph) that comprises of all actors in the Iliad together with their interactions. We present some visualizations of these data and discuss concepts like connectivity, connected components and groupings. Furthermore, we calculate some well-established metrics, coming from social network analysis in this social network and discuss the numerical results. These results indicate that the Iliadic network is a small-world network, rather dissasortative and relatively easy to disconnect.
Diversification of Bw4 Specificity and Recognition of a Nonclassical MHC Class I Molecule Implicated in Maternal–Fetal Tolerance by Killer Cell Ig-like Receptors of the Rhesus Macaque

The rhesus macaque is an important animal model for AIDS and other infectious diseases; however, studies to address NK cell function in this species have been limited by the lack of defined ligands for killer cell Ig-like receptors (KIRs). To identify ligands for rhesus macaque KIRs, we adopted a novel approach based on a pair of stable cell lines. NFAT-responsive luciferase reporter cell lines expressing the extracellular domains of macaque KIRs fused to the transmembrane and cytoplasmic domains of CD28 and CD3ζ were incubated with target cells expressing individual MHC class I molecules, and ligand recognition was detected by the MHC class I–dependent upregulation of luciferase. Using this approach, we found that Mamu-KIR3DL01, -KIR3DL06, -KIR3DL08, and -KIR3DSw08 all recognize Mamu-Bw4 molecules but with differing allotype specificity. In contrast, Mamu-KIR3DL05 recognizes Mamu-A and Mamu-A–related molecules, including Mamu-A1*002 and -A3*13, Mamu-B*036, the product of a recombinant Mamu-B allele with α1 and α2 domain sequences derived from a MHC-A gene, and Mamu-AG*01, a nonclassical molecule expressed on placental trophoblasts that originated from an ancestral duplication of a MHC-A gene. These results reveal an expansion of the lineage II KIRs in macaques that recognize Bw4 ligands and identify a nonclassical molecule implicated in placental development and pregnancy as a ligand for Mamu-KIR3DL05. In addition to offering new insights into KIR–MHC class I coevolution, these findings provide an important foundation for investigating the role of NK cells in the rhesus macaque as an animal model for infectious diseases and reproductive biology.
Increase in Power Conversion Efficiency of Bidirectional DC–DC Converter Using 1:1 Transformer and Pulse-Frequency Modulation Control

This paper proposes a circuit structure of bidirectional dc–dc converter. This structure uses two switches, two capacitors, a 1:1 transformer, and a control circuit for pulse-frequency modulation. The windings of the transformer are connected in a series-aiding configuration to reduce current ripples and to increase power conversion efficiency <inline-formula><tex-math notation="LaTeX">$\eta _{e}$</tex-math></inline-formula>. The capacitors and the leakage inductance of the transformer provide soft-switching conditions. When the proposed converter was designed to operate at a switching frequency of 110–240 kHz, input/output voltages of 100–400 V, and output power <inline-formula><tex-math notation="LaTeX">$P_{o}$</tex-math></inline-formula> of 30–300 W, <inline-formula> <tex-math notation="LaTeX">$\eta _{e}$</tex-math></inline-formula> was ≥97% for <inline-formula> <tex-math notation="LaTeX">$P_{o}\,\geq \,{\text{90}}\,{\text{W}}$</tex-math></inline-formula> and 93.5% at <inline-formula><tex-math notation="LaTeX">$P_{o}\,= \,{\text{30}}\,{\text{W}}$</tex-math></inline-formula>. Experimental results show that the proposed converter is suitable for use in photovoltaic power conversion systems and energy storage systems.
Photonic-Crystal-Fiber-Coupled, Hand-Held, Polarization-Resolved Second-Harmonic-Generation Microscope for In Vivo Visualization of Dermal Collagen Fibers in Human Skin

Second-harmonic-generation (SHG) microscopy is a powerful tool for in vivo monitoring of collagen fibers in human skin. Furthermore, polarization-resolved SHG microscopy can provide additional insights regarding the direction of collagen fibers, i.e., collagen fiber orientation. However, their practical use in the dermatological field is still limited due to the bulky and complicated setup. In this paper, we constructed a photonic-crystal-fiber (PCF) coupled, hand-held polarization-resolved SHG microscope for in vivo monitoring of collagen fibers in human skin. Fiber delivery of ultrashort pulse light was achieved without significant change of the linear polarization by a large-mode-area PCF, whereas the SHG microscopy setup was enclosed into a hand-held probe head. The combination of PCF with the hand-held probe head largely enhances the flexibility of measurement sites in the human skin.
Accurate Operating Analysis of Boundary Mode Totem-Pole Boost PFC Converter Considering the Reverse Recovery of mosfet

The boundary conduction mode (BCM) totem-pole boost power factor correction (PFC) topology is becoming popular in high-efficiency and high power density applications because of its advantages of fewer devices and low conduction losses. The ideal design methodology for the BCM boost converter ignores the reverse recovery of mosfet s’ body diode and the resonance between the inductance and output junction capacitances of switches. However, as the switching frequency increases, these two factors affect the peak value of the inductance current and the switching frequency significantly, which are critical parameters for the boost PFC inductor design. In order to calculate the practical peak current and switching frequency range accurately, this letter proposes an analytical reverse recovery model of the body diode and presents accurate switching cycle operating modes. Either the predicted inductance peak current or the switching frequency range matches the measured result on a 600-W totem-pole boost PFC prototype.
Motion-Controlled Virtual Reality Robotic Arm With Kinect

Kinect is a technology developed by Microsoft that perceives human movements and plays with these movements. On the other hand, virtual reality creates the feeling that we are in an environment that we are not actually in. Purpose of this work is to develop a robotic arm that repeats nonsensitive movement of the person through Kinect and through the camera, it is aimed to see the environment in which the robotic arm is placed virtually. With the combination of Kinect technology and VR technology, full control and realism are provided to the user from a distance. This feature distinguishes the proposed approach from other studies. When human health and work accidents are considered, this system is intended to increase safety and protect human health in dangerous environment.
Comparative Evaluation of Front- and Back-End PFC IPT Systems for a Contactless Battery Charger

Inductive power transfer (IPT) is widely discussed as an alternative to contact charger for plug-in hybrid and electric vehicles. This paper analyzes a contactless battery charger back-end power factor correction (PFC) concept, reducing the primary-side circuit complexity and physical size. For that purpose, the main volume and loss factors of a contactless battery charger are identified, discussing the partitioning of tasks to perform a unity power factor operation. An analysis of the most commonly used front-end PFC and the proposed back-end PFC configuration is performed, with the aim of highlighting benefits and limitations of each variant. Moreover, performance of silicon (Si) and gallium nitride (GaN) devices has also been evaluated, defining the main advantages and drawbacks of both semiconductor technologies in different IPT scenarios. The study is verified experimentally on a 3.2 kW contactless battery charger.
Evaluation of the Use of Exenatide Once-Weekly Suspension Autoinjector Among Patients With Type 2 Diabetes Mellitus and Health Care Professionals

Background: Ease of injection is important to patients. An autoinjector was developed to deliver exenatide, a glucagon-like peptide-1 receptor agonist for type 2 diabetes mellitus. For autoinjection, 0.06-mm exenatide-containing microspheres are suspended in medium-chain triglycerides. Herein, we report design verification and usability testing of the autoinjector for exenatide once-weekly suspension (QWS) delivery. Methods: Exenatide QWS in a single-chamber cartridge is self-injected subcutaneously with three main steps: mix, unlock, and inject. Design verification testing used validated testing methodology. A summative validation study with simulated-use scenarios evaluated unassisted performance on critical tasks (ease of use and the injection process). Results: The autoinjector met specified design requirements for dose accuracy and torque/force. Of 104 participants enrolled (73 lay users, 16 health care professionals, and 15 pharmacists), 90 independently referred to instructions for use during testing. Users successfully achieved critical tasks on first attempt 87-100% of the time. Approximately 78% of participants successfully completed the full injection scenario, including 72% of lay users reporting visual or dexterity impairments. Initial use errors on critical tasks included not mixing well (n = 12), not removing needle cap (n = 8), and not holding needle to the skin for complete injection (n = 5). Untrained injection-naïve and trained injection-experienced lay users made the fewest errors (7% and 3%, respectively). Trained and untrained participants took 2:33 and 5:03 minutes, respectively, to complete a weekly injection. Conclusions: Users with a range of injection experience can rapidly learn to administer exenatide QWS autoinjector correctly, thus minimizing patient effort to manage their diabetes with injectable therapy.
Sexually Transmitted Infections Detected by Multiplex Real Time PCR in Asymptomatic Women and Association with Cervical Intraepithelial Neoplasia

Abstract Objective To determine the frequency of sexually transmitted infections (STIs) in asymptomatic women and the association of STIs with cervical intraepithelial neoplasia (CIN). Methods A cross-sectional study was performed, enrolling women examined in a general gynecology clinic and in a colposcopy referral center from October 2014 to October 2015. The colposcopy group consisted of 71 women, and the general gynecology group consisted of 55 women. Cervical samples were collected for cervical cytology and a multiplex real-time polymerase chain reaction (PCR) was developed to detect human papillomavirus (HPV) and the STIs caused by the following microorganisms: Chlamydia trachomatis, Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma urealyticum, and Neisseria gonorrhoeae. A multivariate analysis was performed by logistic regression, considering the significance level of 0.05. Results The general frequency of STIs was: 46.8% (HPV); 27.8% (C. trachomatis); 28.6% (M. genitalium); 0.8% (M. hominis); 4.8% (U. urealyticum); and 4.8% (N. gonorrhoeae). The significant risk factors for CIN were: HPV infection (odds ratio [OR] = 2.53; p = 0.024); C. trachomatis (OR = 3.04; p = 0.009); M. genitalium (OR = 2.37; p = 0.04); and HPV and C. trachomatis coinfection (OR = 3.11; p = 0.023). After the multivariate analysis, a significant association was found between HPV and CIN (OR = 2.48; 95% confidence interval [95%CI]: 1.04–5.92; p = 0.04); and between C. trachomatis and CIN (OR = 2.69; 95%CI: 1.11–6.53; p = 0.028). Conclusion The frequency of STIs was high in asymptomatic patients. Infections by HPV and C. trachomatis were independently associated with the presence of CIN. The high frequency of STIs in asymptomatic women suggests the need for routine screening of these infections.
A Review of Spread-Spectrum-Based PWM Techniques—A Novel Fast Digital Implementation

Spread-spectrum (SS)-based pulsewidth modulation (PWM) techniques play an important role when tackling the electromagnetic interference (EMI) problem in the switch-mode power supply (SMPS) domain. They achieve the best EMI noise reduction and emerge as a promising and very effective solution to comply with electromagnetic standards. The current work provides an insight into the SS techniques: its history, its types, and mainly its ability to mitigate the EMI problem in the SMPS domain. Moreover, it gives a short review of the different SS-based PWM techniques going from the most basic and simple, i.e., the periodic modulation, to the most developed and complex, i.e., the random and chaotic modulations. Besides, a short review of the different implementation methods was addressed and they were categorized into analog and digital implementation techniques where its pros and cons were provided. Finally, a new fast digital implementation method based on a dsPIC33F microcontroller is presented. Its effectiveness was proved and its advantages over the reviewed implementation techniques were recognized. It reached a 20 dBuV EMI level reduction when the digital chaotic and periodic profiles were embedded into a boost converter prototype.
Feasibility Analysis of Centralized Storage Facilities in Isolated Grids

This paper analyzes the operating and economic benefits anticipated from the introduction of centrally managed battery energy storage systems (BESSs) in noninterconnected island (NII) grids with high renewable energy source (RES) penetration. A mixed integer linear programming based generation management model is developed to simulate the operation of NII systems with and without BESS facilities. The impact of BESS energy and power capacity sizing is discussed, showing that the main contribution of storage lies in the provision of fast response reserves that facilitate the integration of increased intermittent RES generation. A feasibility analysis is then performed, considering BESS facilities either as independent storage investments or as facilities being developed in conjunction with new wind power capacity. The levelized cost of energy or reserves is calculated to evaluate the required remuneration to ensure investment viability.
A Force Myography-Based System for Gait Event Detection in Overground and Ramp Walking

In this paper, we present a novel method to determine the heel strike (HS) and toe-off (TO) during overground (OG) and ramp walking, including the transition. The method utilizes force myography (FMG) signals from thighs while subjects walked on OG and ramp. Five adult male subjects wore a wireless FMG data acquisition system, developed in-house using force resistive sensors and electronic components. A heuristic approach for subject-dependent and terrain-independent model was developed to determine HS and TO in a given gait cycle in steady state and transition. The average error in HS determination was 9.66 ± 8.29, 9.38 ± 9.35, and 13.94 ± 18.95 ms, while TO was determined with an average error of 16.99 ± 18.12, 13.35 ± 15.10, and 17.29 ± 21.92 ms for OG, ramp, and transition, respectively. The proposed system is less expensive, simple to develop, and friendly to wear. The reported errors are comparable to previously reported errors using pressure sensitive insole, gyroscope, accelerometers, and electromyography, which are much complex and expensive in comparison to proposed FMG-based system. Although the tests were conducted on healthy subjects, the system promises to be generalizable to amputee and other pathological gaits also. While the tests were conducted on young adults at self-selected speeds, the system also promises to be generalizable for a wide range of walking speeds across the population.
Improved Intrapixel Thickness Uniformity of Slot-Coated PEDOT:PSS Films for OLEDs via Dilution and Predrying Treatments

Due to capillary force, solution coating of pristine poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS) solution in the presence of banks exhibits poor intrapixel thickness uniformity, shrinking the emission area of organic light-emitting diodes (OLEDs) within pixels. To enhance it, we have applied the predrying treatments (predrying under atmospheric pressure, by heat conduction, and under vacuum) to wet films. However, its impact is minimal because the evaporation rate of wet films is not well-matched to the capillary flow rate of solute during the predrying process. It is tackled by diluting the pristine PEDOT:PSS solution with deionized water such that the evaporation of wet films is retarded and in turn, the convective flow of solute occurs from the pixel edge to the center. With increasing dilution, a noticeable enhancement in its intrapixel thickness uniformity is observed without any sacrifice on the surface morphology. It is found that the predrying effect by heat conduction is more pronounced than that under vacuum. Furthermore, we have demonstrated that slot-die coating rather than spin coating is preferable in the coating of diluted PEDOT:PSS solutions. With the diluted solution and predrying by heat conduction, the thickness uniformity can be enhanced by a factor of 2 and the emission area of OLEDs within pixels is broadened to a great extent.