Miracle-dz/UniFAR-FTUs huggingface dataset:
A Comparison of Similarity Measures for Text Documents

Similarity is an important and widely used concept in many applications such as Document Summarisation, Question Answering, Information Retrieval, Document Clustering and Categorisation. This paper presents a comparison of various similarity measures in comparing the content of text documents. We have attempted to find the best measure suited for finding the document similarity for newspaper reports.
Electrical Impedance tomography : new diagnostic possibilities using regional time constant map

Pulmonary function tests are used to assess the severity of obstructive and restrictive lung diseases. These tests provide information on the whole lung considered as one compartment and can be used to globally describe the physical properties of flow resistance R and compliance C, but do not yield regional information. Electrical impedance tomography (EIT) is widely used in clinical research regarding ventilation monitoring. In this study, EIT recordings were performed simultaneously with spirometry during a forced expiration maneuver. We could show that EIT provides similar results to describe pulmonary mechanics. Therefore, seven patients (814 years) with asthma bronchiale were examined before and after therapy with Salbutamol to perform broncho spasmolysis. We found a relation between flow resistance R and global time constant τglobal with positive correlation r=0.88. Additionally, we propose the use of the regional time constant τreg(x) (RTC-map) as a new imaging modality in a case study which demonstrates its performance considering broncho spasmolysis.
Investigation of High gain MIC power converter for multicrystal PV module employing fuzzy logic technique

A Mutual Inductive Coupled (MIC) DC-DC power converter circuit for Photo-Voltaic (PV) system employing fuzzy logic based maximum power point tracking is presented in this research paper. The proposed DC-DC converter has been modelled and simulated using Matlab-simulink environment for obtaining high gain. The mutually coupled inductor uses one core instead of two or more, which reduces size of the converter. A passive regenerative snubber is exploited for absorbing the energy of stray inductance and also the capacitors are charged in parallel and discharged in series through the mutual coupled inductor for achieving high voltage gain of this converter. The voltage gain characteristics of the MIC converter have been studied for various coupling coefficient, turns ratio of two-winding mutual inductor and duty cycle. Moreover, PV system is conveniently interfaced with proposed power converter for maximizing the solar energy yield and analysed by employing Perturb & Observe (P&O) and fuzzy logic based MPPT algorithms under various operating conditions. The obtained results reveal that, the fuzzy controller provides good improvement in tracking of maximum power and helps to extract considerable amount of additional solar energy from a PV module as compared with P&O algorithm.
THE MITOTIC RESPONSE OF THYMUS‐DERIVED CELLS TO ANTIGENIC STIMULUS

A single thymus lobe from a neonatal donor has the capacity to restore primary immunological competence to a thymectomized syngeneic radiation chimaera. If a cytologically marked thymus graft is used the fate of the introduced cells following antigenic stimulation may be studied. Thymus-derived cells can be found in the spleen and lymph-nodes of such mice and furthermore there is a transient but well-defined increase in the proportion of these cells dividing following an injection of sheep red blood cells or application of a skin homograft 30 days after irradiation and thymus grafting. It was found that an even greater proportion of thymus-derived cells divide in response to a second challenge with sheep cells. Similarly, a higher percentage of thymus-derived cells divide in the lymph-nodes draining a second skin homograft.
Intrusion Detection System by Machine Learning-A Review

Efficient intrusion detection is needed as a defense of the network system to detect the attacks over the network. A feature selection and classification based Intrusion Detection model is presented, by implementing feature selection, the dimensions of NSL-KDD data set is reduced then by applying machine learning approach, we are able to build Intrusion detection model to find attacks on system and improve the intrusion detection using the captured data. With the increasing number of new unseen attacks the purpose of this model is to develop a system for intrusion detection, and the model will be capable of detecting new and previously unseen attacks using the basic signatures and the features of known attack.
A local application of recombinant human fibroblast growth factor 2 for tibial shaft fractures: A randomized, placebo‐controlled trial

Fibroblast growth factor 2 (FGF‐2) is a potent mitogen for mesenchymal cells, and a local application of recombinant human FGF‐2 (rhFGF‐2) in a gelatin hydrogel has been reported to accelerate bone union in our animal studies and preparatory dose‐escalation trial on patients with surgical osteotomy. We have performed a randomized, double‐blind, placebo‐controlled trial in which patients with fresh tibial shaft fractures of transverse or short oblique type were randomly assigned to three groups receiving a single injection of the gelatin hydrogel containing either placebo or 0.8 mg (low‐dosage group) or 2.4 mg (high‐dosage group) of rhFGF‐2 into the fracture gap at the end of an intramedullary nailing surgery. Of 194 consecutive patients over 2 years, 85 met the eligibility criteria, and 70 (24 in the placebo group and 23 each in low‐ and high‐dosage groups) completed the 24‐week study. The cumulative percentages of patients with radiographic bone union were higher in the rhFGF‐2‐treated groups (p = .031 and .009 in low‐ and high‐dosage group, respectively) compared with the placebo group, although there was no significant difference between low‐ and high‐dosage groups (p = .776). At 24 weeks, 4, 1, and 0 patients in the placebo, low‐dosage, and high‐dosage groups, respectively, continued to show delayed union. No patient underwent a secondary intervention, and the time to full weight bearing without pain was not significantly different among the three groups (p = .567). There also was no significant difference in the profiles of adverse events among the groups. In conclusion, a local application of the rhFGF‐2 hydrogel accelerated healing of tibial shaft fractures with a safety profile. © 2010 American Society for Bone and Mineral Research.
Author Profiling for Arabic Tweets based on n-grams

This paper presents an approach for author profiling of an unknown users from their texts produced in social media. In particular, we address the identification of two profile dimensions: gender and language variety, of Arabic twitter users based on their tweets. Our approach focused on applying metaclassification technique on features extracted from tweets body. We explored two main sets of features which are character and word n-grams. The proposed approach allowed us to reach promising results for both language variety and gender identification
The impact and effectiveness of local content policy on oil exploration and production in Brazil

Local content policy plays a fundamental role for Brazil. It is through local content policy that the country is seeking to reconcile expansion of the oil sector with its industrial development. Despite the significant evolution of this policy in recent years, several improvements are needed to balance the objectives of promoting industrialization with the competitiveness of oil exploration and production activity in Brazil. Local content policies have an important positive impact on Brazilian industries, particularly the Brazilian shipbuilding industry. At the same time, local content commitments currently represent an important risk factor for exploration and production (EP) projects in Brazil. The local content commitments are assumed long before the acquisition of product and services for the projects. The risk of cost overruns, delays, and low quality of products is a key consequence of the existing policy, affecting the attractiveness of Brazil’s oil and gas industry. There is a clear space to introduce adjustments in local content policy in Brazil, in order to reduce the potential risks for EP projects, while still supporting industrialization in Brazil. For future projects, allowing greater flexibility to adjust local content commitments as development plans are established would help reduce project risks. Shifting from an approach that penalizes non-compliance to one that rewards operators who exceed commitments would likely represent a more effective incentive structure. For contracts already signed that are unable to meet local content requirements, there is a range of pragmatic adjustments that could be considered in addition to those already mentioned.
Mechanism of Sudden Death Associated with Volatile Substance Abuse

1 Sudden death is a recognized hazard of volatile substance abuse and may occur during exposure or in the subsequent hours. Intoxication may also lead to indirect deaths due to trauma. 2 Specific post-mortem features have not as yet been identified either macroscopically or microscopically in VSA-related deaths. Toxicological examination for volatile substances of all unnatural teenage deaths is strongly recommended. 3 Four mechanisms for acute, direct VSA-related deaths are discussed, viz anoxia, vagal inhibition, respiratory depression and cardiac arrhythmia. Of these, cardiac arrhythmia due to 'sensitization' of the heart to adrenaline is probably the most common and is well documented in experimental conditions. 4 Deaths from cardiac arrhythmia during or soon after VSA are unpredictable, unpreventable and resuscitation is rarely successful. Previous uneventful sessions of abuse provide no protection from this mode of death.
Multiplication and Cytopathogenicity of Mouse Hepatitis Virus in Mouse Cell Cultures.∗

Summary The data presented indicate that MHV (Balb C) multiplies in mouse embryo cell cultures and, after passage in that system, in mouse kidney epithelium and L cells. In all these systems a cytopathic effect was observed after serial passage. These observations provide convenient techniques for studying in vitro this and perhaps other strains of mouse hepatitis virus.
A Great Place to Work For All : Better for Business, Better for People, Better for the World Ed. 1

Greatness Redefined for the 21st Century Today's business climate is defined by speed, social technologies, and people's expectations of “values” besides value. As a result, leaders have to create an outstanding culture for all, no matter who they are or what they do for the organization. This groundbreaking book, from the creators of the gold-standard Fortune 100 Best Companies to Work For list, shows how it's done. Through inspiring stories and compelling research, the authors demonstrate that great places to work for all benefit the individuals working there and contribute to a better global society—even as they outperform in the stock market and grow revenue three times faster than less-inclusive rivals. This is a call to lead so that organizations develop every ounce of human potential.
ADAPTATIONAL PROCESS OF PARENTS OF PEDIATRIC ONCOLOGY PATIENTS

This study, based on grounded theory, explores the adaptational process of parents of pediatric oncology patients. Thirty-two Taiwanese parents (26 mothers and 6 fathers) were interviewed. Data were collected through individual in-depth and focus group interviews, observations, medical chart review, nurses' note, and researchers' reflexive journals. The findings suggest that parents adapt to their children's cancer by a dynamic process; i.e., they modify their coping tasks and related strategies as clinical events (e.g., diagnosis, side effects, relapses, or death) occur. This adaptational process consisted of five components: confronting treatment, maintaining family integrity, establishing support, maintaining emotional well-being, and searching for spiritual meaning. Related factors such as coping tasks are described.
Creating an IT risk maturity model for distributed ledger applications

There are currently only a limited number of organizations which adopting applications that use Distributed Ledger Technology. This is in part due to the risks involved with the technology. This research proposes a new IT Risk DLT Application Maturity Model which can be used by businesses to asses risks of DLT and enhance their development processes. A multi-method research approach is used to create the model. Through a literature study risk are collected which are proposed to a panel of 15 field experts from industry. This resulted in a total of 48 risks divided over 5 risk ares and 14 sub-risk ares which are verified through five small case studies. From the collected risks, maturity level descriptions are created for each of the sub-risk areas. The maturity of an application can be assessed using a number of assessment questions which result in a maturity level for each sub-risk visualized through a dashboard. The model currently has a number of criteria before it can be applied to an application. One of these criteria is the use of IoT technology by the application. Furthermore, a number of risk areas still provoked disagreements under experts and should be examined further.
Skills for Employment in the Environment Profession: Insights from Australia

Like other professionals, the skills expected to be exercised by those working in the professional environment and sustainability sector cover a wide range. There has been considerable discussion given to what this range embraces, and which are the more important of the skills. Also discussed has been the terminology associated with skills; i.e. core skills, generic skills, transferable skills, competencies, capabilities, and more. An electronic survey of environment professionals based in Australia provided the opportunity to explore the skills that a sample of these professionals considered to be important in their professional work. The results indicated that the critical generic skills for being an environmental professional are: communication (written); project management; interpersonal skills; judgment and decision making; scientific approach and application; team work (coordination); initiative and enterprise; and computer skills. Considering others’ work regarding other professions, it appears that many of the skills in this list are also relevant to a range of professions. Further, the broad relevance of these skills is indicated as the survey participants considered them to be important for specific (current) jobs and for working in the sector generally. Surprisingly critical thinking, which is often noted in the literature as a high priority, was considered important for current positions, but not so for working in the sector generally. Also, the participants indicated little appreciation of aspects of ‘normative skills’; suggesting that practitioners are focused on skills needed for ‘getting the job done’, but show little recognition of what the ‘job is and its implications’. The results provide a snap-shot of the profession, and point to areas of research regarding the skills that future environment, and other, professionals will need, and how educational institutions will have to respond; given fast moving climate change, alongside the continuing roll-out of automation in work-places.
Getting More Organs for Transplantation.

Organs for transplantation are a scarce resource. Paying to increase the supply of organs is illegal in much of the world. We review efforts to increase transplantation by increasing the supply of available organs from living and deceased donors. Progress has been made in increasing the availability of living donor kidneys through kidney exchange. Recent legislation in Israel aims at encouraging deceased donation by awarding priority for receiving organs to registered donors. We also explore the manner in which organ donation is solicited and present evidence to suggest that some recent movement towards "mandated choice" may be counterproductive.
Swimming drafting simulation using a k − ω turbulence model

It is now well known that swimming drafting leads to a reduction in energy spent to overcome drag forces (friction, wave and pressure) and enhances gains time in competitive swimming (Chatard et al. 1998; Vennell et al 2006; Bixler et al. 2007; Brisswalter and Hausswirth 2008). In underwater swimming, the flow past a swimmer induces a trailing adverse pressure gradient area in its near wake. Swimming drafting behind and close to another swimmer consequently leads to a reduction in pressure drag induced by the lead swimmer. To our knowledge, the only study in literature dealing with numerical analysis of drafting in swimming is the one of Silva et al. (2008) using computational fluid dynamics (CFD) in two-dimensional (2D) configuration and where the distance between swimmers varied in the range 0.5 , d , 8.0m. This study differs from this work as far as it focuses on a shorter distance between swimmers (0 ,d , 0.5m) in touch with the experimental conclusions by Chatard and Wilson (2003).
PAK2 is cleaved and activated during hyperosmotic shock‐induced apoptosis via a caspase‐dependent mechanism: Evidence for the involvement of oxidative stress

Hyperosmotic shock elicits a stress response in mammalian cells and can lead to apoptotic cell death. In the present study, we report that hyperosmotic shock can induce activation of a 36 kDa kinase detected by an in‐gel kinase assay in several cell types, including mouse Balb/c 3T3 fibroblasts, and human Hep 3B and A431 cells. This 36 kDa kinase can be recognized by an antibody against the C‐terminal region of a family of p21Cdc42/Rac‐activated kinases (PAKs) on immunoblot. Further studies with this antibody and a PAK2‐specific antibody against the N‐terminal region of PAK2 demonstrate that hyperosmotic shock can induce cleavage of PAK2 to generate a 36 kDa C‐terminal catalytic fragment in cells. The cleavage and activation of PAK2 was found to be closely associated with both DNA fragmentation and activation of an ICE/CED‐3 family cysteine protease termed caspase‐3 in hyperosmotically shocked cells. Furthermore, pretreating the cells with two caspase inhibitors (Ac‐DEVD‐cho and Ac‐YVAD‐cmk) could inhibit both cleavage/activation of PAK2 and DNA fragmentation induced by hyperosmotic shock. Moreover, all these hyperosmotic shock‐induced changes (i.e., activation of caspase‐3, cleavage/activation of PAK2, and DNA fragmentation) in cells could be blocked by antioxidants such as ascorbic acid (vitamine C), α‐tocopherol (vitamine E), dithiothreitol, β‐mercaptoethanol, and glutathione. Taken together, our results show that PAK2 is cleaved and activated via a caspase‐dependent mechanism during hyperosmotic shock–induced apoptosis and suggest the involvement of antioxidant‐preventable oxidative stress in inducing this process. J. Cell. Physiol. 178:397–408, 1999. © 1999 Wiley‐Liss, Inc.
Quantitative cortical synapse proteomics of a transgenic migraine mouse model with mutated CaV2.1 calcium channels

Familial hemiplegic migraine type 1 (FHM1) is caused by missense mutations in the CACNA1A gene that encodes the α1A pore‐forming subunit of CaV2.1 Ca2+ channels. Knock‐in (KI) transgenic mice expressing CaV2.1 Ca2+ channels with a human pathogenic FHM1 mutation reveal enhanced glutamatergic neurotransmission in the cortex. In this study, we employed an iTRAQ‐based LC‐LC MS/MS approach to identify differentially expressed proteins in cortical synapse proteomes of Cacna1a R192Q KI and wild‐type mice. All expression differences determined were subtle and in the range of 10–30%. Observed upregulated proteins in the mutant mice are involved in processes, such as neurite outgrowth and actin dynamics, vesicle turnover, and glutamate transporters. Our data support the view that in Cacna1a R192Q KI mice, several compensatory mechanisms counterbalancing a dysregulated glutamatergic signaling have come into effect. We propose that such adaptation mechanisms at the synapse level may play a role in the pathophysiology of FHM and possibly in the common forms of migraine.
Collaboration Technologies Decrease Reliance on Radio Communication in Simulated Air Battle Management

Radio has been the dominant collaboration technology in military aviation, but may not be optimal owing to channel overload and static interference. The current study sought to examine how team communication was changed when radio was augmented by text-based chat, a virtual whiteboard, and two ecological resource displays in a simulated air defense task. To accomplish this, twenty-one five-person teams performed the simulation with goals to protect friendly assets, eliminate enemy aircraft
Natural genetic variation and hybridization in plants

RNA clusters remain poorly understood due to our inability to completely sequence these regions. As technology advances it will be possible to obtain near-complete descriptions of genetic variation in natural populations. This will provide the oppor-tunity to examine patterns of variation in relation to environmental adaptation at unprecedented resolution in space and time. As our climate continues to change, understanding global patterns of natural genetic variation and its relationship to plant adaptation will thus be of critical importance.
Robotic-Assisted Surgery for Rectal Adenocarcinoma: Short-term and Midterm Outcomes From 200 Consecutive Cases at a Single Institution

BACKGROUND: Although robotic surgery is increasingly used in the management of rectal cancer, its oncologic safety remains uncertain. OBJECTIVE: We aimed to evaluate the feasibility and safety of robotic-assisted rectal cancer resection in terms of short-term and midterm outcomes. DESIGN: A prospectively collected set of samples was retrospectively evaluated. SETTINGS: Data included in this study were collected at a single institution from 2007 to 2011. PATIENTS: The study included 200 consecutive rectal cancer patients. INTERVENTION: The patients underwent robotic-assisted resection surgery performed by a single surgeon. MAIN OUTCOME MEASURES: The short-term (surgical outcome and pathologic data) and midterm outcomes (local pelvic control and overall and disease-free survival) were evaluated and compared with those in the published literature. RESULTS: The median patient age was 60 years, and the male:female ratio was 2:1. The median distance of rectal tumors from the anal verge was 6 cm. Preoperative radiotherapy was performed in 55 patients. The median operation time was 270 minutes, and the median blood loss was 190 mL. Grade 3 to 5 complications, according to the Clavien-Dindo classification, were observed in 15 patients (7.5%). The circumferential resection margin was positive in 5 patients (2.5%). During the median follow-up period of 29.8 months, recurrence occurred in 27 patients (distant metastasis, 18 patients; local recurrence, 7 patients; and both local recurrence and distant metastases, 2 patients). The local pelvic control and overall and disease-free survival rates of stage III patients at 5 years were 93.0%, 88.6%, and 76.6%. LIMITATIONS: This was a retrospective, uncontrolled study of selected patients by a single surgeon. CONCLUSIONS: Our results demonstrated an acceptable morbidity and a low rate of positive circumferential resection margin with effective local control. We also achieved excellent survival data. The midterm oncologic safety justifies the practice of robotic rectal cancer resection to further investigate its role on long-term outcomes.