Miracle-dz/UniFAR-FTUs huggingface dataset:
Synergistic Effects of Adding A Substrate and an Organic Reductant for Stimulating the Bioremediation of 4-Chloronitrobenzene-Contaminated Soil

Background: Soil contaminated with 4-chloronitrobenzene (4NCB) is resistant to microbial degradation due to the electron-withdrawing properties of the nitro and chloro groups in 4NCB. Currently, sufficient information is not available on how to use biostimulation strategies to enhance the bioremediation of 4NCB-contaminated soil.Results: In the present study, a novel strategy was developed by utilizing the synergistic effects of adding an organic reductant (ascorbic acid, VC) and an organic nitrogen source (peptone) to stimulate the biodegradation of 4NCB-contaminated soil. Using this strategy, the bioremediation of 1 g-4NCB/ kg-1 soil could be completed within 8 days in soil batch reactors. Furthermore, the study discovered two 4NCB cometabolic intermediates in the soil reactors added with peptone and VC, and for the first time, 4NCB was transformed to 4-chlorofromanilide.Conclusion: The proposed strategy is promising because it is highly efficient, easy to control and involves a non-toxic, environmentally friendly substrate/reductant. ). Finally, this approach warrants future studies to extend its applications to soils contaminated with other nitroaromatic compounds.
Groundwater Potential Assessment Using Geoelectrical Data: A Case Study Of Phuket Island, Thailand

Groundwater is the dominant source of water supply on Phuket island, Thailand. The water demand on Phuket has been increasing due to rapid urbanization and population growth. A scarcity of freshwater and over-extraction of groundwater may shortly become severe problems for Phuket. Geoelectrical data obtained by Vertical Electric Sounding (VES) were employed in this study to estimate the Dar Zarrouk parameters of the study area. Twenty-four VES stations were set up using Schlumberger configuration with a 1.0 m minimum spacing. The lithology layers from 24 unpublished borehole data indicating each subsurface layer were validated with the resistivity data obtained from VES. The geoelectric profiles gave a maximum of three layers with varying resistivities and thicknesses across each VES station. Two parameters (longitudinal conductance and transverse resistance) of the Dar Zarrouk model were calculated from VES data to generate the thematic maps in a GIS environment, thus the groundwater potential in Phuket Island was represented as a single map by using the weighted overlay technique in ArcGIS, based on both longitudinal conductance and transverse resistance. The groundwater potentials were classified into three potential levels (low, medium, and high). The results reveal that the highest groundwater potential areas are isolated and in specific locations, while the majority of area has medium level groundwater potential. Finally, the low potential zones are in the flank and the top parts of the study area.
Multilevel Step-Down Resonant Switched-Capacitor Converters With Full-Range Regulation

Multilevel resonant switched-capacitor converters (RSCCs) have drawn attention in large step-down voltage conversion but are hindered in a wide area of applications due to limited voltage regulation range. A new full-range regulation (FR) method for multilevel step-down RSCCs is proposed in this article. As an example of the proposed FR method, the fixed on-time modulation for modified Dickson RSCC is provided. In addition to full-range voltage regulation, the multilevel RSCCs with the proposed FR method feature complimentary driving signals, zero voltage switching turn-on for switches, zero current switching turn-off for diodes, even switch voltage stress, even diode voltage stress, high active switch utilization, high efficiency, and high power density. A modified Dickson RSCC prototype was built to validate the proposed FR method. The proposed FR method is further extended to series-parallel RSCCs and Fibonacci RSCCs.
Mapeamento do ambiente térmico de aviários de postura abertos em sistema vertical de criação

Objetivou-se, com este trabalho monitorar, em tempo real, o ambiente termico de um aviario de postura e realizar o mapeamento completo da distribuicao das variaveis temperatura do ar, umidade relativa do ar e indice de temperatura e umidade no alojamento. O trabalho foi conduzido no mes de janeiro de 2013 em uma granja comercial de aves de postura, sistemas verticais, com seis andares de gaiolas. O aviario e totalmente automatizado possuindo 100.000 aves alojadas na densidade de 300 cm2 ave-1. A partir dos dados coletados foram determinadas as medias de temperatura e umidade relativa do ar para periodo diurno e noturno de diferentes posicoes na instalacao. Os mapas termicos resultantes demostram que ocorreu uma variabilidade termica em diferentes posicoes espaciais no interior do aviario, com a regiao central apresentando temperaturas superiores as das extremidades porem dentro da faixa de conforto termico das aves considerando a situacao de temperaturas medias, durante calor extremo a temperatura interna na instalacao alcancou 33 oC. A umidade relativa do ar apresentou pequenas variacoes durante o dia e maiores no periodo da noite. Em relacao ao indice de temperatura e umidade a maior parte da instalacao permaneceu dentro da faixa de conforto.
Premedication of nalbuphine benefits children gastrointestinal endoscopy screening under sedation: a randomized, controlled, double-blinded clinical trial

Backgrounds: Nalbuphine may be a useful opioid for postoperative use in children, but exact efficacy of premedication of nalbuphine in gastrointestinal endoscopy (e.g. compared to other commonly used opioids) has not been determined yet. This study aims to compare the benefits between premedication with nalbuphine and fentanyl on children undergoing gastrointes­tinal endoscopy screening under sedation with propofol. Methods: A total of 460 children with age 3-10 years old, undergoing elective gas­trointestinal endoscopy screening with ASA I -II were randomly assigned to fentanyl group or nalbuphine group, and then they were all subsequently ad­ministrated propofol through target-controlled infusion (TCI) with an effect-site concentration of 3.5 ug/ml, before and during the procedure. We compared postoperative pain, the total consumption of propofol, the cardiovascular parameters, satisfaction scores of patients’ parents, adverse events in patients, injection pain scores and recovery time.Results: The postoperative pain score at time of entering PACU and 10min later in nalbuphine group were lower than that in fentanyl group(1.75±1.87 vs 2.29±2.22 p＜0.05)(1.67±1.81 vs 2.12±1.99 p＜0.05), but the injection pain of propofol and the recovery time is approximate. Patients in two groups had similarly stable hemodynamics. The consumption of propofol was higher in fentanyl group than nalbuphine group (78.7± 13.6 mg vs 71.2 ± 13.9 mg, P <0.05). The incidence of bucking/hiccupping was lower than in the nalbuphine group than that in the fentanyl group (6% vs 14.3%, P <0.005). The incidence of body movement was also lower in the nalbuphine group than the fentanyl group (7.9% vs 18.7%, P<0.005). The satisfaction scores by patients ’parents were higher in the nalbuphine group than fentanyl group (4.9 ± 0.3 vs 4.7 ± 0.5, P<0.05). The incidence of pruritus is lower in the nalbuphine group compared to fentanyl group. (1.0% vs 4.8% P <0.05)Conclusion: Premedication of nalbuphine in children for endoscopy screening sedation has many benefits. The analgesic effect of nalbuphine is superior to that of fentanyl.
Cardiovascular outcomes of antidiabetes medications by race/ethnicity: A systematic review and meta-analysis.

BACKGROUND The consistency of cardiovascular risk reduction by antidiabetes medications across racial and ethnic groups remains unclear. The aim of this study was to analyze racial/ethnic patterns in the results of cardiovascular outcomes trials of antidiabetes medications in people with type 2 diabetes. METHOD PubMed and Cochrane library databases were searched from the inception dates to December 2020. Cardiovascular outcome trials in type 2 diabetes that randomized participants to antidiabetes medication or control treatment and reported results by race/ethnic groups or region were included. RESULTS A total of 19 studies were included in this meta-analysis. Among White participants, treatment with antidiabetes medications significantly decreased the risk of composite cardiovascular outcomes when compared with placebo treatment (OR = 0.88, 95% CI 0.83-0.94, p < 0.05). Among Asian participants, antidiabetes medications also significantly decreased the risk of composite cardiovascular outcomes when compared with control treatment (OR = 0.80, 95% CI 0.74-0.86, p < 0.05). A similar pattern was found when analyzing the effects of antidiabetes medications vs. control treatment in other racial/ethnic groups comprising mostly Hispanics and Pacific Islanders (OR = 0.87, 95% CI 0.78-0.98, p < 0.05). However, among Black participants, treatment with antidiabetes medications resulted in nominal but non-significant decreases in the composite cardiovascular outcomes when compared with control treatment (OR = 0.84, 95% CI 0.62-1.14, p = 0.26). CONCLUSIONS The present meta-analysis showed cardiovascular safety of antidiabetes medications in people with type 2 diabetes from all racial/ethnic groups studied; however, significant composite cardiovascular risk reductions were demonstrated only in White and Asian participants. To determine whether antidiabetes drugs confer consistent cardiovascular benefits in Black and other racial/ethnic participants requires more investigations in the future.
Effect of seaweed (Ecklonia maxima) extract and legume-derived protein hydrolysate biostimulants on baby leaf lettuce grown on optimal doses of nitrogen under greenhouse conditions

In recent years, the demand for green leafy vegetables is increasing. In order to satisfy this trend, the leafy crops are cultivated under high energetic inputs, especially high doses of nitrogen (N) fertilization that leads to a nitrate accumulation in leaves, sometimes overcoming the legal threshold set by the European Community for their commercialization. The nitrate in leaves can be dangerous for human health because in the human body it can be converted into nitrite, which can cause methemoglobinemia or create cancer-causing compounds. In order to overcome this problem, a correct N management is needed, especially using technical means which can improve the nitrogen use efficiency. In this study, we evaluated the possible effect of two important plant biostimulants on yield and quality traits (nitrate, antioxidants activity, carotenoids) of baby leafy lettuce, grown in a greenhouse with three levels of nitrogen input. Nitrogen doses were 0, 10 (sub-optimal) and 20 (optimal) kg ha -1 , N0, N10 and N20 respectively. The biostimulants were Ecklonia maxima seaweed extract (3 ml per liter) (named Bio 1), legume-derived protein hydrolysate (Bio 2) and non-treated control (Control). The treatments were distributed in a randomized complete-block design with three replications (3 N levels x 3 Biostimulant applications x 3 replications). Biostimulant applications of seaweed extracts and legume-derived protein hydrolysate improved yield and LAI: 13.4% and 12.0% increase over non treated plants, respectively. The highest yield was reached at 20 kg N ha -1 . Application of foliar biostimulants stimulated the antioxidant systems of plants, improved leaves color and increased chlorophyll and carotenoids content. The nitrate concentration in leaves was increased under higher levels of N fertilization, meeting the EC legal limit at N20 treatment in plants sprayed by E. maxima seaweed extract. Therefore, in our growth conditions, it seems possible to reduce nitrogen input at 10 kg N ha -1 , by applying additional applications of biostimulants to reduce the yield gap upon application of N20 treatment.
Influence of nitrogen flow during sintering of bismuth manganite ceramics on grain morphology and surface disorder

ABSTRACT Bismuth manganite ceramics, consisted of two phases: cubic I23 and orthorhombic Pbam, were obtained by high-temperature sintering in the air. The powdered ceramics were sintered in gaseous nitrogen flow at stabilized temperature of TS = 870–1120 K for 4 h. Grain structure and chemical composition were checked by scanning electron microscopy (SEM). We observed changes in the grain shapes, the number and size of the hexagon-based parallelepipeds increased. The X-ray diffraction (XRD) test has shown that the orthorhombic BiMn2O5 phase formation was favored. The local disorder was tested by X-ray photoemission spectroscopy. Multi-component lines assigned to O 1s, Mn 2p, Bi 4f were detected. The ratio of intensities of particular components was influenced by the sintering conditions. The shape of valence band was not influenced by the sintering conditions. Electric resistivity was measured in 200–750 K range with the use of Ag and In electrodes. The activation energy increased slightly when the sintering temperature increased.
Impact of Immune Checkpoint Inhibitor Therapy on The Overall Survival in Elderly Patients With Non-Small Cell Lung Cancer

Purpose: We analyzed the relationship between a history of immune checkpoint inhibitor and overall survival in patients with non-small cell lung cancer (NSCLC) aged ≥ 70 years. Methods: We conducted a retrospective analysis of the data of patients with NSCLC aged ≥70 years old who had received systemic anticancer therapy at our institution between 2015 and 2019. Results: The analysis included the data of a total of 63 patients, including 36 patients who had received immune checkpoint inhibitor therapy and 27 patients who had not received treatment with an immune checkpoint inhibitor. Univariate analysis revealed a longer overall survival in patients who had received treatment with an immune checkpoint inhibitor as compared to those who had not received treatment with an immune checkpoint inhibitor (median: 17.2 vs. 9.8 months; p = 0.026, log-rank test). Multivariate analysis revealed a significant association between a history of treatment with immune checkpoint inhibitors and the overall survival (hazard ratio, 95% confidence interval: 0.42, 0.20-0.86; p = 0.019, Cox proportional hazards model). A significant interaction was also observed between a history of treatment with an immune checkpoint inhibitor and the tumor histology (p = 0.006), the association between the overall survival and a history of immune checkpoint inhibitor therapy being stronger in the non-small cell lung cancer patients with squamous cell carcinoma than in those with adenocarcinoma. Conclusion: A significant association between history of immune checkpoint inhibitor therapy and the overall survival was detected in elderly NSCLC patients aged ≥70 years old in a clinical practice setting. Our results also suggested that the impact of immune checkpoint inhibitor therapy on the survival differed depending on the tumor histology.
Breathing aerodynamics and interactions with odontogenesis

The morphological evolution of human dentition is a complex developmental phenomenon. While a group of genes encoding for transforming growth factor (TGF), fibroblast growth factor (FGF), and homeobox superfamily are responsible for controlling the entire procedure, the underlying local regulatory mechanisms remain unknown to a great extent [1]. Considering the intimate temporal and spatial relationships through developmental phases of teeth and adjacent craniofacial structures, mutual interactions seem highly plausible. While breathing, air influx leads to partial dehydration of gum pads. Respiratory air flow enhances the viscosity and stiffness of mucosal tissues [2]. However, the pattern of dehydration is closely dependent on the respiratory route structures, e.g. tongue, which affect breathing aerodynamics and hence the exposure of mucosal surfaces to air flow [3]. While posterior surfaces are more rapidly dehydrated due to proximity to air flow, coverage of anterior surfaces by tongue diminishes this effect. Hence, functional movements of oral structures with resultant mechanical strains and microdeformations more profoundly affect the anterior low-stiffness areas. The fact that physiological habits such as suckling affect the anterior gum pads exaggerates the aforementioned mechanical strains. Microdeformations and tissue strains are perceived as mechanical signals by living cells [4]. Moreover, transforming growth factor-b (TGFb) and fibroblast growth factor (FGF), both of which are important odontogenic factors, are affected by mechanical strain [5,6]. Collagen fibers and other piezoelectric tissues structures when affected by mechanical strain generate piezoelectric current which acts synergistically with TGF-b [7,8]. The aforementioned respiration-dependent dehydration gradient with subsequent web of biological events leads to site-specific expression of certain genes necessary for the development of odontomorphogenesis. The proposed hypothesis suggests that infant respiratory function is an important component of odontogenesis. Moreover in the light of present hypothesis certain therapeutic approaches, e.g. mucosal moisturizers, may be developed to affect odontomorphogenesis through modulation of mechanical properties of mucosa.
Consumption of fruit in street posts from eleven iberoamerican countries. Multicentric study

Introduction: The street food intake is a very common practice in working people. There is a great supply of street food; fruits are always part of this offer and can be found in different presentations Objetive: To analyze the frequency of fruit consumption in public roads in Latin America. Material and Methods: A cross-sectional study was carried out using a questionnaire of 15 questions in Google Docs format, which was validated by Delphi method and applied in 11 countries: Argentina, Brazil, Chile, Colombia, Costa Rica, Guatemala, Panama, Paraguay, Peru, Portugal and Uruguay. Results: It was surveyed 8885 people, over 50% consume food on public roads; among the most consuming countries, it is highlighted Colombia (78%) and Guatemala (76%), followed by Peru (66%). With respect to fruit consumption on public roads, it is observed that there is higher consumption in Portugal (61%), followed by Colombia (55%) and Guatemala (51%), and the countries with less consumption are Argentina (26%) and Uruguay (20%). Fruit consumption in the street is the same in both sexes in the most countries. On the other hand, in Portugal, Colombia, Argentina, Costa Rica and Chile, the highest consumption correspond to people with higher education (university or post-graduate) (p<0.05). Conclusion: Street food consumption is high in all countries, including consumption of fruits. This can be transformed into an opportunity to encourage their consumption, but street posts must be adjusted to the necessary requirements to offer safe food.
Investigation of methane adsorption on molecular sieve zeolite (from natural materials)

In this study, Kaolin, Bentonite, and Feldspar were used as a low-cost source of Si and Al to synthesize the molecular sieve 13X. The synthesized Zeolites were characterized by XRD, FTIR, SEM, TGA, and BET analysis and used as a suitable adsorbent for CH4 adsorption. The surface areas were 591, 505, 472, and 588 m2/g for natural kaolin (13X-K), bentonite (13X-B), feldspar (13X-F) and commercial molecular sieve 13X (13X–C), respectively. The 13X-K had the highest thermal stability than 13X-B and 13X-F. The adsorption capacities (pressure >20bar) of 13X (kaolin), 13X (bentonite), and 13X(feldspar) were 3.6, 2.4, and 1.95 mmol/g, respectively. The adsorption data were fitted to some isotherms including Langmuir, Freundlich, Sips, BET, and Toth. It was found that the Sips model showed better fitting in comparison to other models. The thermodynamic of adsorption was also investigated; the positive value of ∆S_ads^0 revealed the increased randomness at the solid-solution interface during the gas adsorption. The thermodynamic study also indicated that the adsorption process was exothermic and spontaneous. The adsorption capacities of synthesized 13X samples were compared to other adsorbents; it was found that 13X–K showed considerable performance and can be introduced as a suitable adsorbent for applications on a large scale.
Photoluminescence studies of Eu3+ ions doped calcium zinc niobium borotellurite glasses

Europium ions doped TRZNB glasses were prepared by melt quenching technique using commercial powders through mixing the specific weights of batches. The compositions prepared were 10TeO2 + 15RO + 5ZnO + 10Nb2O5 + 59B2O3 + 1Eu2O3 (where R= Mg, Ca and Sr). We report, the photoluminescence and decay analysis of Eu -doped TRZNB glasses. The luminescence spectra and decay times were measured at 395 nm excitation. The photoluminescence spectra consist of five emission bands originating from the D0 metastable state to FJ (J = 0 4) lower lying states. The phenomenological Judd–Ofelt (J–O) intensity parameters, Ω2 and Ω4 were obtained from the emission intensities of D0→ F2 and D0→ F4, respectively by taking the magnetic dipole D0→ F1 emission band intensity as reference. The radiative parameters such as spontaneous emission probabilities ( ), lifetimes (τm), branching ratios (βm) for different excited states have been predicted theoretically. The decay profiles were fitted to the single exponential equation for all the three glasses. The spectroscopic properties confirmed the potentiality of present TRZNB glasses doped with Eu ions as a laser host materials to produce an intense red luminescence at 616 nm corresponding to D0 → F2 emission level and have significant importance in the development of emission rich optical systems.
Global Paradoxes and Provocations in Education

Global trends in education are accompanied by both paradoxes and provoca-tions. The paradoxes constitute inherent educational dilemmas, such as the paradox of institutional education, wherein social rules and mandatory tasks are played out as a means of imparting lessons about freedom and independence. Our argument in this chapter is that we should reconsider the ‘future’ of planned and controlled education and instead become open to the perceptions of two groups that are at the forefront of educational futures – namely, children and young people and various experts on children and childhood. They meet face to face or indirectly on a daily basis in various educational contexts, and their experiences are interdependent and often paradoxical. This chapter explores possible sustainable futures in education as articulated by children, youth and child experts and highlights several qualities that sustainable futures will require, in relation to UNCRC article 28; children’s right to education and article 29; that education must develop every child’s personality, talents and abilities to the full.
Aplicación y evaluación de la gamificación en la docencia universitaria: una experiencia docente

Resumen En este trabajo se presenta la experiencia de diseñar e implementar una estrategia de gamificación en la docencia universitaria. El objetivo final de esta innovación era combinar mecánicas y dinámicas del juego, de tal forma que, en conjunto, formaran una herramienta docente capaz de repercutir en la motivación del alumnado hacia la participación y mejora en su desempeño. La información obtenida de los estudiantes, a través de cuestionarios y entrevistas semiestructuradas, muestra, por una parte, que la estrategia de gamificación fue percibida como útil para su aprendizaje y atractiva para su experiencia educativa, y por otra, que mejora la participación y el rendimiento del estudiante en la asignatura.