Miracle-dz/UniFAR-FTUs huggingface dataset:
Cervical screening in 20–24-year olds

The paper by Rieck et al. on pages 64–71 of this issue of the Journal of Medical Screening provides the justification for continuing to invite women aged 20–24 for cervical cancer screening in Wales. The decision to screen always involves a balance between harms (including costs) and benefits, and we believe that the benefits should clearly outweigh the harms since those harmed are not necessarily the same as those who benefit from screening. With regard to cervical screening in women aged 20–24 years, we still feel that the evidence of the benefits outweighing the harms is too weak to recommend population screening. Rieck and colleagues start by reviewing the literature relating to cervical screening in women aged 20–24, with particular emphasis on the natural history of high-grade cervical lesions, and then consider the effect of screening in young women on incidence, mortality and screeninginduced morbidity. Most of the literature reviewed was published prior to the recommendation of the Advisory Committee on Cervical Screening to the Minister in 2003 and virtually all of the remainder was available to the Committee at that time. With the exception of the data from Wales collated for the first time in the Rieck et al. paper, the decision to recommend cessation of screening in women aged 20–24 was therefore based on the same evidence as that considered by Rieck and colleagues. How have the two groups come to opposite conclusions?
1-(4,6-Diethoxypyrimidin-2-yl)-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one.

In the title compound, C15H15N5O3S, two parallel intermolecular N-H.S hydrogen bonds, forming an eight-membered ring, link two molecules into a dimer unit; these dimer units linked into a chain of edge-fused rings by weak C-H.O hydrogen bonds.
ARAŞTIRMA YAZISI ORIGINAL ARTICLE İSKEMİK İNMEDE METABOLİK SENDROMUN SIKLIĞI VE MORTALİTEYE ETKİSİ

OBJECTIVE: Stroke is one of the leading causes of death in world populations and leads to substantial disability and labor loss in the population. Risk factors for stroke are important in terms of preventive medicine. Early diagnosis and treatment of patients having risk factors for stroke can prevent stroke. Metabolic syndrome (MetS), which is characterized by insulin resistance, and prothrombotic and proinflammatory processes, has become one of the important risk factors in the last century owing to its effects on mortality and morbidity. The present study aimed to investigate the effects of MetS on mortality in ischemic stroke. MATERIAL and METHODS: One hundred and thirty-seven patients (81 females and 56 males) without a previous stroke, who were diagnosed with ischemic stroke in the Neurology Clinic, within the 24 hours of the disease, evaluated in terms of etiopathogenesis, and fulfilled or not fulfilled the MetS criteria, were randomly included. RESULTS: The mean age was 69.78±10.76 years for the whole study group, 66.32±12.04 years for males and 72.18 ±9.12 years for females. MetS was present in 67 (48.9%) of 137 patients. Forty-six (56.8%) of 81 female patients and 21 (37.5%) of 56 male patients had MetS. With regard to mortality rates of patients with and without MetS; 7 (25.9%) of 16 patients who died within the first 10 days had no MetS, whereas 9 (37.5%) had MetS. Eleven (40.7%) of 19 patients who died between the 10th and 30th days had no MetS, whereas 8 (33.3%) had MetS. Nine (33.3%) of 16 patients who died between 3 months and 1 year had MetS, whereas 7 (29.2%) patients had no MetS. CONCLUSION: One-year evaluation of the patients with ischemic stroke revealed that MetS risk factor had no effect on mortality rates.
3‐Methyl‐1H‐quinoxalin‐2‐one

In the crystal structure of the title compound, C9H7N2O, one-dimensional chains of planarmolecules are interlocked at a dihedral angle of about 30° and display weak aromatic interactions, consistent with π–π stacking. The distance between quinoxaline rings in two neighbouring planes is 3.972 (6) A. Within a chain, molecular dimers, which are held together by a pair of strong intermolecular N—H⋯O hydrogen-bonding interactions at a distance of 2.792 (4) A, are linked by weak ditopic hydrogen-bonding interactions C—H⋯N at a distance of 3.560 (6) A.
cis-Tetracarbonyl[4-fluorophenyl)-diphenylphosphine-P](piperidine-N)-molybdenum(0).

The title molecule, [Mo[P(C6H5)2(C6H4F)](HNC5H10)(CO)4] or [Mo(C18H14FP)(C5H11N)(CO)4], has irregular octahedral geometry about the Mo atom. The molecules form a complicated hydrogen-bonded network comprising C-H.O, C-H.F and C-H.pi hydrogen bonds and pi-pi interactions. The C-H.pi and pi-pi interactions form chains containing C-H.pi/pi-pi dimers linked via C-H.pi interactions and the chains are linked into a three-dimensional network via C-H.O and C-H.F hydrogen bonds.
N'-[2-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene]-4-nitrobenzohydrazide

The title compound, N'-[2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin- 10(2H)-yl)ethylidene]-4-nitrobenzohydrazide (1), was obtained by the reaction of formylmethylflavin and p-nitrobenzohydrazide. The product 1 inhibited the DNA binding of nuclear factor-κB, and was characterized by 1H-NMR, 13C-NMR, electrospray ionization mass spectrometry, elemental analysis, IR and UV.
Effects of endothelin-1 on the contraction of Ito cells (fat-storing cells).

コラゲナーゼ灌流法およびcentrifugal elutriation rotorにより分離し24時間培養したラット培養伊東細胞を用いて,エンドセリン-1 (ET-1)による伊東細胞の収縮能について検討した. この培養伊東細胞は胞体内にビタミンAを含有し,種々の方向に伸展した細胞質にデスミンの局在を認めた. 125I-ET-1を用いた光顕的オートラジオグラフィーによる観察で培養伊東細胞表面に125I-ET-1のgrainが多数集積していた. 培養液中へ各種濃度(0～800nM)のET-1を添加した60分後の培養伊東細胞の面積は,ET-1濃度の増加とともに濃度依存性に明らかに減少した. また,ET-1を含む培養液を除去して120分後,培養伊東細胞はET-1添加前の面積に近い値まで回復した. 以上の結果より,ET-1は伊東細胞に作用し伊東細胞を収縮させ,伊東細胞が肝類洞の血流調節に深く関与している可能性が示唆された.
Evaluation of atmospheric circulation connections in the Atlantic-European region with moisture characteristics of the troposphere over the Black Sea

The results of the mutual spectral analysis of mean NAO index values and the values of mean moisture content and moisture during the warm period of the year from 1973 to 2016 confirm the existence of statistically significant relationships interlatitudinal large-scale atmospheric circulation of the atmosphere in the Atlantic-European region with the characteristics of the hydrologic cycle of the Black Sea region with a probability of more than 65%, which makes it possible to use them to forecast the dynamics of the moisture content of the variability in the troposphere region.
Interlayer reflections of chirp signals over Khabarovsk – Tory path in February 2014

In this work, the morphological investigation of maximum observed frequencies (MOF) and delays of interlayer signal over latitudinal path Khabarovsk – Tory in February 2014, has been carried out. Along with MOF and delays of regular 1F, 2F, 2E modes of high-frequency propagation we registered parameters of 1FN and 2Es modes. As a result of our study, we conclude that the interlayer signal is registered most often in the day time. This is connected with the E layer presence. At night time registration of 1FN mode is stipulated with the Es-layer presence over the decameter wave signal propagation path. Wave-like variations of MOF1FN and MOF2Es are registered on February 24 and February 28, 2014.
Dual-color quantum dot structured illumination microscopy using single LED

Structured illumination microscopy (SIM) is a kind of wide-field super-resolution (SR) imaging technique which can double the resolution than convenient microscope. Because it doesn’t need any special fluorescent labels and high illumination intensity, it’s an ideal technique for high frame multicolor subcellular imaging in large field of view. Nevertheless, most of the previous multicolor SIM schemes use multiple excitation light to excite different fluorescence labels sequentially, not only making the system complex, but also limiting the ability to observe dynamic interaction between subcellular structures. Quantum dot (QD) is a kind of novel fluorescence label which has a wide absorption spectrum. Utilizing this special property of QD, we present a simple solution of multicolor SIM. The solution uses only a single LED as excitation light source and keep the ability to simultaneous image different colors. To demonstrate the capabilities of our system, we imaged the Blue-ray disc labeled by dual-color QDs.
Tongue segmentation algorithm for traditional Chinese medicine based on convolutional neural network

Tongue diagnosis is an important part of the Traditional Chinese Medicine (TCM) diagnosis. In Chinese Medicine, tongue body reflects the most sensitive indicators of the physiological function and pathological changes, which has important application value in the process of diagnosis and treatment of the TCM diagnosis. The accurate separation of tongue body from tongue image is the premise of recognition and diagnosis. Most of the proposed tongue segmentation algorithms are based on the improvement of traditional approaches. These algorithms can improve the segmentation accuracy of tongue image to some extent, but they are less robust. To address above problems, a method of fast tongue image segmentation algorithm using convolutional neural network is proposed in this paper. The network is inspired from ShuffleNet which provided an efficient classification and detection network. The running time of our structure is about 0.16s, and the average segmentation precision is about 90.5%, which makes it of great potential for real-time applications. As opposed to the two common traditional segmentation methods (Kmeans++, GrabCut), the proposed method performs better than the above algorithms.
Surface impedance of the "thin ice-sea" structure

For calculations of the electromagnetic field of the two-layer "thin ice-sea" structure, the areas of applicability of the impedance boundary conditions are determined depending on the thickness of the ice and the angle of incidence of the vertically polarized wave. Results are needed to calculate the attenuation function W and the radio wave field level. It is shown that for the "thin ice-sea" structure, taking into account the dependence of surface impedance on the angle of incidence is important for over-the-horizon radar systems in the HF range of radio waves. In the VHF range for ice 80 cm thick, frequency bands are identified in which impedance boundary conditions are applicable.
Comparison of the year-to-year and seasonal variability of aerosol characteristics under urban and background conditions from measurements at the Aerosol Station and the Fonovaya Observatory in 2014-2018

The analysis of data of monitoring measurements at the Aerosol Station of IAO SB RAS (suburbs of the city of Tomsk) and in the background region (Fonovaya Observatory) in 2014-2018 has allowed us to reveal the opposing character of tendencies in the annual average aerosol and Black Carbon (BC) concentrations (increase at the suburban station and decrease under background conditions). Maximal (in the annual dynamics) differences of the mass concentrations of submicron aerosol and BC between the measurement sites were found in winter, especially, in January and February. A significant growing trend of the BC fraction under urban conditions by 7% per year was discovered. In the background region, no significant trends were observed in the year-to-year dynamics of aerosol and BC characteristics. Peculiarities of the annual dynamics and year-to-year variability of the anthropogenic contribution from the city to average values of aerosol characteristics were analyzed.
Changes of the absorption properties of aerosol from Siberian wildfires due to atmospheric aging: analysis of satellite observations

Carbonaceous aerosol originating from forest fires and other types of open biomass burning (BB) is known to have a strong impact on the radiative balance of the atmosphere but available model estimates of the corresponding climate effects are characterized by large uncertainties due to insufficient knowledge of its sources and atmospheric transformations (aging). Here we study the atmospheric aging of BB aerosol by analyzing data of satellite measurements of the absorption and extinction aerosol optical depths (AAOD and AOD) in BB plumes from wildfires in Siberia. Along with the aerosol measurements, our analysis involves satellite data for CO column amounts as well as the simulations of the BB aerosol photochemical age using a chemistry transport model. The analysis includes the two main stages. First, we study the BB aerosol evolution as a function of its photochemical age by using the observations over Siberia in the period from May to September of 2012. Second, we examine changes in the BB aerosol optical characteristics in the smoke plumes that had been transported from Siberia into the European part of Russia in July of 2016. The results indicate that photochemical aging strongly affects the behavior of both AAOD and AOD. The results also show that aged BB aerosol becomes less absorptive at the near UV wavelength range, indicating a depletion of brown carbon in particles. The BB aerosol aging effects detected at the both stages of the analysis are found to be consistent.
Application research on health monitoring of Sutong Bridge based on distributed optical fiber sensing

In this paper, combining with the tenth anniversary load test of Sutong Bridge, we proposed the Brillouin Optical Time Domain Analysis (BOTDA) to conduct health monitoring research on the bridge, and completed the following three aspects: Firstly as an auxiliary measure of strain monitoring, monitor the level of stress and strain along the longitudinal bridge to each position. Secondly through the parking of the vehicles at different positions on the bridge pavement, the influence lines on the overall structural stress of the bridge are obtained. Thirdly through the long-term strain monitoring of the bridge, the impact of the usual traffic load information on the bridge strain is obtained.The results show that the technology not only breaks through the monitoring bottleneck of traditional point sensors, but also realizes distributed measurement of strain on the transmission path; it can also be used for real-time monitoring, damage identification, crack location, settlement monitoring of traffic load information of bridges and other structures. Compared with the traditional sensor test results, the effectiveness and frontier of the technology are proved, and the significance of the distributed fiber-optic sensor technology for the health monitoring of major structures such as bridges is fully explained.
Study on feature extraction algorithm of mobile robot vision SLAM under dynamic illumination

When a feature point detection method is used in vision SLAM to match images, environment condition around the robot is uncertain usually. Many influence factors such as rotation, scale, fuzzy as well as illumination in the process of detection have a strong impact on robot's locating and incremental map building. Experiments proved that SIFT, SURF, BRISK, ORB and FREAK have good robustness under normal illumination. However, the illumination is complex in practical applications, and the stability of image features extraction will be affected. Based on a mobile robot vision platform, the speed, repetition rate and matching rate of five feature extraction algorithms above are compared and analyzed with different methods. Under dynamic illumination, the robustness and matching effect of image features with translation, rotation, scale and fuzzy transformations are also compared. Through experimental data analyzing, BRISK features shows better effect under dynamic illumination.
Design of a medical micro pressure sensor based on the conducting rubber film

Pressure sensors have many applications in medical fields. Conducting rubber film with good piezoresistive characteristics was synthesized and used for a special micro pressure sensor design. The film features adjustable measurement range, good mechanical robustness, and room-temperature fabrication. The resistance-pressure curve was measured, and the repeatability was checked. The specially designed micro sensor can be used for the measurement of human body liquid pressure.
Supercontinuum generation in graded index multimode fiber pumped by superluminescent pulse amplification

Graded-index multimode fibers attracted interest in nonlinear regime for their unique nonlinear dynamics characteristics. We report the supercontinuum generation pumped by a superluminescent pulse amplification in graded-index multimode fiber. Efficient supercontinuum was generated and the beam profile cleanup was observed. The speckle characteristics of this supercontinuum is measured and compared to another supercontinuum induced by a homemade mode-locked fiber laser. It is found that the supercontinuum generated by superluminescent pulse amplification attains a smoother speckle structure and lower optical coherence. Our results indicate that the superluminescent pulse amplification could be a more effective means to produce low coherent supercontinuum sources than traditional lasers.
Association Between Isokinetic Knee Strength and Perceived Function and Patient Satisfaction With Sports and Recreational Ability After Matrix-Induced Autologous Chondrocyte Implantation

Background: Returning to a sound level of activity after matrix-induced autologous chondrocyte implantation (MACI) is important to patients. Evaluating the patient’s level of satisfaction with his or her sports and recreational ability is critical. Purpose: To investigate (1) satisfaction with sports and recreational ability after MACI and (2) the role that knee strength plays in self-reported knee function and satisfaction. Study Design: Case-control study; Level of evidence, 3. Methods: Isokinetic knee strength was assessed in 97 patients at 1, 2, and 5 years after MACI to calculate hamstrings-quadriceps ratios and peak knee extensor and flexor torque limb symmetry indices (LSIs). The Sports and Recreation subscale of the Knee injury and Osteoarthritis Outcome Score (KOOS Sports/Rec) was completed. A satisfaction scale was used to evaluate how satisfied the patients were with their ability to return to recreational activities and their ability to participate in sport. Associations between knee strength LSI, KOOS Sports/Rec, and satisfaction with recreational and sporting activities were assessed through use of multivariable linear and logistic regression, with adjustment for confounders. Mediation analysis was conducted to assess the extent to which self-reported knee function mediated associations between strength LSI and satisfaction. Results: Satisfaction with the ability to return to recreational activities was achieved in 82.4%, 85.6%, and 85.9% of patients at 1, 2, and 5 years, respectively, and satisfaction with sports participation was achieved in 55.7%, 73.2%, and 68.5% of patients at 1, 2, and 5 years, respectively. Knee extension torque LSIs were associated with KOOS Sports/Rec after adjustment for confounders over 1, 2, and 5 years (5-year regression coefficient, 6.0 points; 95% CI, 1.4-10.7; P = .012). KOOS Sports/Rec was associated with the likelihood of being satisfied at all time points (recreation: 5-year adjusted odds ratio [OR], 2.26; 95% CI, 1.48-3.46; P < .001; and sports: 5-year adjusted OR, 1.98; 95% CI, 1.47-2.68; P < .001). In a multivariable mediation model, the knee extension torque LSI was associated with satisfaction directly (standardized coefficient, 0.16; 95% CI, 0.03-0.28; P = .017) and indirectly via KOOS Sports/Rec (standardized coefficient, 0.19; 95% CI, 0.01-0.38; P = .027), the latter representing 55% of the total association of knee extension torque LSI with satisfaction. Conclusion: Knee extensor symmetry was associated with satisfaction in recreational and sporting ability, both directly and indirectly, via self-reported sports and recreation–related knee function. Restoring strength deficits after MACI is important for achieving optimal outcomes.
Nutritional Adequacy of the Daily Stuff at the University Canteens: The Case of a Philippine University

One of the services that a college or university offers to her students is food service. The school canteen can serve as an avenue for developing proper food habits, supporting nutrition education and observing table etiquette. The school canteen can also help reduce nutritional problems by offering and promoting a good selection of economical but nutritious, palatable and sanitary foods. The purpose of this study is to determine the nutritional qualities of the foods regularly sold and consumed by the students and employees at the school canteens. Ten snack items were subjected to analysis to determine their calorie and nutritive values. The study revealed that most of the snack foods do not meet at least one-fifth of the recommended energy and nutrient intake (RENI) for adolescents ages 16 to 18 years for calories, proteins, thiamin, riboflavin, niacin, calcium and iron. It is suggested that regular evaluation of nutritional qualities of food be conducted to ensure the consumption of wholesome food leading to improved health and well-being.
An Ontology-Mediated Space Science Digital Repository

The Planetary Data System, NASA’s official archive for Solar System Exploration data, has transitioned to an archival information system based on ISO standards for the long-term preservation of digital data. The ontology-based PDS4 Information Model provides the informational requirements to address the system’s mission to efficiently collect, archive, and make accessible the digital data and documentation produced by or relevant to NASA’s planetary missions. Adopted internationally, this ontology-mediated information system brings together inputs from a variety of sources in an open and interoperable fashion.
LABO: An Ontology for Laboratory Test Prescription and Reporting

LABO is an ontology formalizing laboratory test prescriptions and reporting documents. It is built according to the OBO Foundry methodology, and is a component of a core ontological model that aims to enable interoperability between various clinical data sources in the context of a Learning Health System. This article presents LABO, distinguishing between directive entities and data items, and using the relations directs and is about to represent their connections with the relevant laboratory test processes.
The Process of Building Patient Trust in Health Information Exchange (HIE): The Impacts of Perceived Benefits, Perceived Transparency of Privacy Policy, and Familiarity

Exchange technologies such as health information exchanges (HIE) currently lack acceptance theories that consider not only cognitive beliefs that result in adoption behavior but also emotional factors that may influence adoption intention. Based on the theory of reasoned action (TRA), the technology-adoption literature, and the trust literature, I theoretically explain and empirically test the impact that perceived benefits, perceived transparency of privacy policy, and familiarity have on cognitive trust and emotional trust in HIE. Moreover, I analyze the effect that cognitive trust and emotional trust have on individuals’ intention to opt into HIE and their willingness to disclose health information. I conducted an online survey using data from individuals who knew about HIE through experiences with providers that participated in a regional consumer-mediated HIE network. In my SEM analysis, I found empirical support for the proposed model. My findings indicate that, when patients know more about HIE benefits, HIE sharing procedures, and privacy guidelines, they feel more in control, more assured, and less at risk. The results also show that patient trust in HIE may take the forms of intentions to opt in to HIE and patients’ willingness to disclose personal health information that providers exchange through the HIE. I discuss the implications my results have for both academics and practitioners.