Miracle-dz/UniFAR-FTUs huggingface dataset:
DOES INCOME SMOOTHING IMPROVE INFORMATIVENESS OF STOCK PRICES

The purpose of this research is to get empirical evidence from effect Income smoothing to Informativeness of Stock Prices in Indonesian Stock Exchange (IDX). Population from this research is take from companies that have been listing Index LQ 45 in IDX form 2003 until 2015. Income Smoothing is masured by Jones’s Model which have been modified by Kothari et. all (2005). Informativeness of stock price using Zarowin and Tucker Model (2006) Future Earnings Response Coeficient, and the relations to earnings persistence, which is can been seen from relation from current earnings dan future earnings. The research is using data from year 2003 until 2015 period, and year 2014 used as terminal year. That found income smoothing have a negative effect to informativeness of stock price and also found the managers’ i ncome smoothing action always decreases earnings from 2013 to 2015. Current earnings have related to future earnings.
Nurse staffing in relation to risk-adjusted mortality in neonatal care

Objective: To assess whether risk-adjusted mortality in very low birthweight or preterm infants is associated with levels of nursing provision. Design: Prospective study of risk-adjusted mortality in infants admitted to a random sample of neonatal units. Setting: Fifty four UK neonatal intensive care units stratified by: patient volume; consultant availability; nurse:cot ratios. Patients: A group of 2585 very low birthweight (birthweight <1500 g) or preterm (<31 weeks gestation) infants. Main Outcome Measure: Death before discharge or planned deaths at home, excluding lethal malformations, after adjusting for initial risk 12 hours after birth using gestation at birth and measures of illness severity in relation to nursing provision calculated for each baby’s neonatal unit stay. Results: A total of 57% of nursing shifts were understaffed, with greater shortages at weekends. Risk-adjusted mortality was inversely related to the provision of nurses with specialist neonatal qualifications (OR 0.67; 95% CI 0.42 to 0.97). Increasing the ratio of nurses with neonatal qualifications to intensive care and high dependency infants to 1:1 was associated with a decrease in risk-adjusted mortality of 48% (OR: 0.52, 95% CI: 0.33, 0.83). Conclusions: Risk-adjusted mortality did not differ across neonatal units. However, survival in neonatal care for very low birthweight or preterm infants was related to proportion of nurses with neonatal qualifications per shift. The findings could be used to support specific standards of specialist nursing provision in neonatal and other areas of intensive and high dependency care.
Accounting, Analysis And Auditing Of Information Regarding Tangible Assets In The Romanian Economic Entities

Unlike the companieswho are incorporated with the purpose of obtainingprofit, the non-profit organizations and public institutions are functioning based on varioussources of funding. The present work aims at the recognition in the accounts of the fixed assetsamounted to those three types of entities. In this process we have started to study the accountingrules applicable to these entities, as well as specialized works of recent date. The aspects studiedand presented with regard to the definition, initial evaluation and subsequent evaluation werefollowed by a comparison of their types for the entities subject to study, and then present acomparative statement of recording in the accounts of major operations relating to the fixedassets. Finally, we present some information regarding the indicators of financial and economicanalysis that uses the value of the fixed assets and some aspects which are examined by theauditor in his objective opinion regarding the tangible assets. It may be noted that tangibleassets occupies an important place in the life of an entity and that the reflection of them in theiraccounting provides the same information, even though the accounting formulas used aredifferent. But what makes the difference in accounting is closely related to the specific of theeconomic entity analyzed and the information they must submit to users of accountinginformation.
Are we making progress in preventing Barrett's-related esophageal cancer?

Despite the increased awareness and recognition of Barrett's esophagus, the incidence of EAC continues to rise sharply in the Western world. Attempts to improve outcomes for this deadly disease rely on the detection of BE; unfortunately, the majority of EAC patients never receive a prior diagnosis of BE. Additionally, endoscopic surveillance has limitations. Studies have demonstrated suboptimal biopsy sampling among practicing gastroenterologists, and the determination of dysplasia, the basis of risk stratification in BE, is associated with relatively low interobserver agreement. Candidate biomarkers are under investigation for the identification of patients at highest risk for neoplastic progression, although these have not yet been prospectively validated. Endoscopic therapies are effective for the treatment of high-grade dysplasia and intra-mucosal carcinoma. However, the use of these techniques for BE patients without dysplasia cannot currently be recommended for the prevention of EAC. There are no current chemo-preventive agents that can be advocated for use in all BE patients. Hopefully, the AsPECT study will shed light on the roles of both PPIs and aspirin for the prevention of EAC. It is hoped that current and future research will ultimately provide enough answers to help slow the epidemic rise in incidence of esophageal adenocarcinoma.
Arginine and pyrimidine biosynthetic defects in Neisseria gonorrhoeae strains isolated from patients

Neisseria gonorrhoeae strains with nutritional requirements that include arginine (Arg-), uracil (Ura-), and hypoxanthine have attracted attention because of their tendency to cause disseminated infections, as a basis for genetic studies of arginine and pyrimidine biosynthesis, we examined the activities of four enzymes of these pathways in cell-free extracts of both prototrophic and Arg- Ura- strains. Activities of glutamate acetyltransferase, aspartate transcarbamylase, and orotate phosphoribosyltransferase, encoded respectively by argE, pyrB, and pyrE, were absent in some Arg- Ura- isolates. Gonococci that were unable to utilize ornithine for growth in place of citrulline lacked activity of carbamyl phosphate synthetase (encoded by car). Defects of car imposed requirements for both citrulline (or arginine) and a pyrimidine because of the dual role of carbamyl phosphate in the two pathways. Defects of argE, car, pyrB, and pyrE were separately introduced by genetic transformation into representatives of a gonococcal strain which initially was prototrophic. Results of enzyme assays of these isogenic auxotrophic transformants confirmed the gene-enzyme relationships.
World Agricultural Resources and Food Security: International Food Security

The purpose of this chapter is to analyze the impact of public agricultural Research and Development (R&D) investments on agricultural productivity and long-term food security to derive policy recommendations. The methodological approach is based on the application of the state-of-the art Computable General Equilibrium (CGE) model to R&D. By endogenizing R&D in global CGE models, it is possible to assess the impact of different public R&D policies on the food availability and food access of food security. This study found that R&D investments bring positive effects on the food access dimension of food security, particularly in places such as Sub-Saharan Africa where prices are expected to grow significantly by 2050, as agricultural land becomes scarcer and more expensive. Doubling the R&D intensity would soften the land constraints and substantially decelerate food prices, thus preventing the deterioration of living standards of rural households and leading to a gain in daily caloric consumption. The impact of alternative agricultural R&D policies on the various dimensions of food security has not been analyzed using a CGE framework, which enables capturing both the benefits and costs from R&D investments. Modeling the dynamic accumulation of R&D stocks makes it possible to analyze the effects of R&D on food security over time. Frontiers of Economics and Globalization Volume 17 ISSN: 1574-8715 DOI: 10.1108/S1574-871520170000017001 Copyright © 2017 by Emerald Publishing Limited All rights reserved
Intracellular Calcium Changes and Chemosensitivities of Human Epidermoid Carcinoma Cell Lines after Exposure to Cisplatin

In order to elucidate the mechanisms of cisplatin (cis-diamminedichloroplatinum; CDDP)-resistant tumor cells, we previously established a CDDP-resistant KB cell line (KBrc cells) from a parental KB cell line derived from epidermoid carcinoma (KB cells). The KBrc cells were resistant to 5 kinds of platinum (Pt) drugs. Intracellular Pt concentrations in KBrc cells were lower than in KB cells. Decrease of intracellular Pt concentrations was one of the CDDP-resistant mechanisms. When we measured changes of intracellular calcium ion concentration ([Ca2+]i) during exposure to high-dose CDDP, a sustained elevation of the [Ca2+]i level was observed in the KB cells. These results suggest that the mechanisms underlying CDDP resistance involve changes in calcium channels and an alteration of calcium homeostasis in the tumor cell line.
Nonneural Congenital Abnormalities Concurring with Myelomeningocele: Report of 17 Cases and Review of Current Theories

Objective: Meningomyelocele (MMC) is a common central nervous system birth defect. Various congenital and acquired abnormalities have been reported with MMC, some of which are secondary to the pathophysiology and some are morbidities of the underlying disease. The aim of this study was to discuss current possible theories explaining diverse anomalies/abnormalities seen in a series of 390 patients with MMC. Methods: A retrospective study was performed using the records of 390 patients with MMC at Children’s Hospital Medical Center in Tehran, Iran, from January 2001 to January 2007. A series of 17 cases of MMC with attributed organ anomalies, not explained by a causal effect of the underlying disorder, were compiled. There were 3 cardiac anomalies including ventricular septal defect, pulmonary artery atresia and tetralogy of Fallot, 4 musculoskeletal malformations, consisting of missing rib, polydactylia and complex distal limb anomaly, 4 urological anomalies such as bladder exstrophy, horseshoe kidney and dysplastic kidneys, 2 occipital encephaloceles, 2 congenital adrenal hyperplasia patients with ambiguous genitalia, 1 omphalocele, 1 albinism and 1 Klippel-Feil syndrome. A review of the literature and discussion explaining each of these observations, have been performed and some possible theories have been proposed.Conclusions: Although various organ anomalies with different embryological origin had been observed and reported with MMC, it is difficult to explain their development using one of the current theories of MMC formation. It could be attributed to a possible genetic defect or merely an incidental finding. A teratological insult during the embryogenic phase would be an alternative assumption.
Localized Proxy-MIPv6 with Route Optimization in IP-Based Networks

Proxy Mobile IPv6 (PMIPv6) is designed not only to avoid tunneling overhead over the air but also to manage the mobility of hosts that are not equipped with any mobility management software. However, PMIPv6 leads to increasing signaling cost as mobile nodes move frequently because the protocol is based on the global mobility management protocol. In this letter we propose Localized PMIPν6 with Route Optimization (LPMIPv6-RO). Our numerical analysis shows that the proposed scheme outperforms previously proposed mobility protocols in terms of both signaling and packet delivery cost.
Net Clinical Benefit of Adding Clopidogrel to Aspirin Therapy in Patients With Atrial Fibrillation for Whom Vitamin K Antagonists Are Unsuitable

BACKGROUND Adding clopidogrel to aspirin therapy reduces stroke in patients with atrial fibrillation (AF) but increases hemorrhage. OBJECTIVE To quantify the net benefit of adding clopidogrel to aspirin therapy, accounting for differences in clinical significance between ischemic and hemorrhagic events. DESIGN Observational cohort study to assign the relative weighting of events and post hoc analysis of randomized trial data to assess net benefit of dual antiplatelet therapy in the ACTIVE (Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events) clinical trials. SETTING Global randomized clinical trial. PATIENTS 10,041 patients with AF, 7554 of whom were not candidates for warfarin therapy. MEASUREMENTS Ischemic events (ischemic stroke or myocardial infarction) and hemorrhagic events (hemorrhagic stroke or subdural or extracranial bleeding), weighted by the hazard ratio for death (or death or disability) after an event relative to death (or death or disability) after ischemic stroke. The net clinical benefit of dual antiplatelet therapy in the ACTIVE A trial participants was defined as the sum of weighted event incidence with dual antiplatelet therapy subtracted from the sum of weighted event incidence on control treatment, expressed as ischemic stroke equivalents prevented per 100 patients years. RESULTS Adding clopidogrel to aspirin therapy prevented 0.57 ischemic stroke equivalent (95% CI, -0.12 to 1.24) per 100 patient-years of treatment when weighted by hazard for death after ischemia or hemorrhage and 0.67 ischemic stroke equivalent (CI, -0.03 to 1.18) when weighted by death or disability after ischemia or hemorrhage. LIMITATION No attempt was made to relate deaths used for weighting to events; disability data were missing for more than one half of patients. CONCLUSION Adding clopidogrel to aspirin therapy resulted in a modest net benefit among patients with AF for whom warfarin was unsuitable. The benefit would probably be clinically relevant for some patients, but estimates could not exclude the possibility of either no benefit or very small harm in this population. PRIMARY FUNDING SOURCE Bristol-Myers Squibb and sanofi-aventis.
The Data Driven Decision RACE in eRetailing

This study takes a customer centric approach to investigate small eRetailers’ data driven decisions. The research is based on an edited version of Chaffey and Smith´s (2013) RACE framework and an edited version of the business analytics framework by Delen and Demirkan (2012a), divided in knowledge and data driven decision-making. By combining these two frameworks we create the Data Driven Decision RACE model. The empirical research is a survey among small Finnish eRetailers. The findings indicate that a majority of the studied eRetailers do analyze data and understand customer online behavior especially in the Reach and Engage stages of the Data Driven Decision RACE model. However, the study also indicates that the data driven decision-making is fairly low within all three stages of the model, which implies that small eRetailers primarily rely on experience and gut instinct rather than on customer data when they make decisions concerning their online activities. and happened
Consumer evaluations of trend imitation: brand equity, consumer attitudes and preference

This paper aims to uncover consumer evaluations of high-priced traditional retail luxury brands and more affordable neo-mass luxury retail brands when they imitate the innovative designs of one another. ,Using a scenario inspired by a lawsuit involving admitted copying practices, this study used a one-way (time of product introduction: the traditional luxury brand launches the product design before the neo-mass luxury brand vs the neo-mass luxury brand launches the product design before the traditional luxury brand) between-subjects experimental design to examine the effect of time of product introduction (such that consumers are aware of imitation practices) on brand attitude, brand equity (measured via the dimensions of brand associations, brand image, brand credibility and brand leadership) and brand preference. ,Results reveal that consumer awareness of imitation practices is important in determining changes in brand equity, brand attitude and brand preference, regardless of luxury brand type. The research also indicates that consumers evaluate traditional luxury brands that engage in imitation practices more negatively than neo-mass luxury brands that do so. ,This research provides a deeper understanding of consumer response to imitation practices, along with managerial insight for luxury brands operating in that sphere. Limitations and future research directions are also offered. ,This study appears to be one of the first to investigate imitation practices by using stimuli inspired by a copycat case, and one of few that assesses consumer evaluations of imitation by existing brands.
Abdominal Malignant Mesothelioma Following Autologous Bone Marrow Transplantation: A Case Report

Secondary malignancies are a well-known late complication occurring in patients who undergo bone marrow transplant (BMT) during childhood. A boy with acute lymphoblastic leukemia experienced a BM relapse at the age of 14 years and underwent an autologous BMT conditioned with TBI and melphalan. Sixteen years later a malignant mesothelioma of the peritoneum was diagnosed. A surgical approach according to the Sugarbaker technique and hyperthermic peritoneal perfusion with CDDP and Adriamycin were performed. The patient is alive and well after a follow-up of 20 months. To the authors' knowledge this is the first case of mesothelioma as a secondary malignancy after BMT.
What Determines Meridional Heat Transport in Climate Models

AbstractThe annual mean maximum meridional heat transport (MHTMAX) differs by approximately 20% among coupled climate models. The value of MHTMAX can be expressed as the difference between the equator-to-pole contrast in absorbed solar radiation (ASR*) and outgoing longwave radiation (OLR*). As an example, in the Northern Hemisphere observations, the extratropics (defined as the region with a net radiative deficit) receive an 8.2-PW deficit of net solar radiation (ASR*) relative to the global average that is balanced by a 2.4-PW deficit of outgoing longwave radiation (OLR*) and 5.8 PW of energy import via the atmospheric and oceanic circulation (MHTMAX). The intermodel spread of MHTMAX in the Coupled Model Intercomparison Project Phase 3 (CMIP3) simulations of the preindustrial climate is primarily (R2 = 0.72) due to differences in ASR* while model differences in OLR* are uncorrelated with the MHTMAX spread. The net solar radiation (ASR*) is partitioned into contributions from (i) the equator-to-pole cont.
Neural control of gene recruitment in metazoans

Gene recruitment played a critical role in metazoan evolution. Yet, there is no consensus on whether it is an accidental event or a result of an inherent “gene recruiting” mechanism. The prevailing opinion among biologists is that gene recruitment results from random changes in genes or their regulatory regions, but the supporting evidence is poor and controversial. Herein, I present a mechanism in which gene recruitment is a neurally determined event, an adaptive response to changes in environmental conditions. In support of the hypothesis, I present evidence on the manipulative expression of genes in the central nervous system, as well as neurally determined examples of gene recruitment in transgenerational developmental plasticity and in evolution of metazoans Developmental Dynamics 240:1–8, 2011. © 2010 Wiley‐Liss, Inc.
Effect of Price, Brand and Product Quality of Life Insurance Sales Volume in Conjunction

This study aims to determine the effect of price, brand, and product quality to the Volume of Sales at Joint Life Insurance. The research object is the Joint Life Insurance. In this study, the samples are employees of the Joint Life Insurance. Total population is observed as many as 150 people with a total sample of 109 people. Sample collection technique is Random Sampling technique The research evidence using multiple linear regression analysis, t test, and test F. Based on the analysis performed using multiple linear regression with the help of statistical program SPSS version 20.0 in getting results indicating that there is influence between variables Price, Brand and Product Quality of the sales volume in the Joint Life Insurance. From the analysis of the t test can be concluded that the variable Price, Brand and Product Quality significant effect on sales volume in the Joint Life Insurance While F-test analysis results can be concluded that the variable Price, Brand and Product Quality influence simultaneously on Sales Volume on the Joint Life Insurance.
Zombies on the road: a holistic design approach to balancing gamification and safe driving

This paper explores novel driving experiences that make use of gamification and augmented reality in the car. We discuss our design considerations, which are grounded in road safety psychology and video game design theory. We aim to address the tension between safe driving practices and player engagement. Specifically, we propose a holistic, iterative approach inspired by game design cognition and share our insights generated through the application of this process. We present preliminary game concepts that blend digital components with physical elements from the driving environment. We further highlight how this design process helped us to iteratively evolve these concepts towards being safer while maintaining fun. These insights and game design cognition itself will be useful to the AutomotiveUI community investigating similar novel driving experiences.
Coherent Phonon Heat Conduction in Superlattices

Coherent Heat Flow Typically, heat in solids is transported incoherently because phonons scatter at interfaces and defects. Luckyanova et al. (p. 936) grew super-lattice films made from one to nine repeats of layers of GaAs and AlAs, each 12-nm thick. Thermal conductivity through this sandwich structure increased linearly with the number of superlattice repeats, which is consistent with theoretical simulations of coherent heat transport. Coherent phonon transport is evidenced by linear increases of thermal conductivity with total superlattice thickness. The control of heat conduction through the manipulation of phonons as coherent waves in solids is of fundamental interest and could also be exploited in applications, but coherent heat conduction has not been experimentally confirmed. We report the experimental observation of coherent heat conduction through the use of finite-thickness superlattices with varying numbers of periods. The measured thermal conductivity increased linearly with increasing total superlattice thickness over a temperature range from 30 to 150 kelvin, which is consistent with a coherent phonon heat conduction process. First-principles and Green’s function–based simulations further support this coherent transport model. Accessing the coherent heat conduction regime opens a new venue for phonon engineering for an array of applications.
Fuzzy multi-objective reactive power clearing by a fuzzy adaptive PSO approach

This paper presents a fuzzy multi-objective approach for clearing the reactive power market. The object functions that have been studied are the total payment function (TPF), voltage stability and the voltage deviation of the buses. All of the object functions are transformed to membership functions and then a pseudogoal function is derived to express a unique object function. The proposed reactive market is implemented to the IEEE 30-bus system.