Miracle-dz/UniFAR-FTUs huggingface dataset:
Abbreviation Detection in Vietnamese Clinical Texts

Abbreviations have been widely used in clinical notes because generating clinical notes often takes place under high pressure with lack of writing time and medical record simplification. Those abbreviations limit the clarity and understanding of the records and greatly affect all the computer-based data processing tasks. In this paper, we propose a solution to the abbreviation identification task on clinical notes in a practical context where a few clinical notes have been labeled while so many clinical notes need to be labeled. Our solution is defined with a semi-supervised learning approach that uses level-wise feature engineering to construct an abbreviation identifier, from using a small set of labeled clinical texts and exploiting a larger set of unlabeled clinical texts. A semi-supervised learning algorithm, Semi-RF, and its advanced adaptive version, Weighted Semi-RF, are proposed in the self-training framework using random forest models and Tri-training. Weighted Semi-RF is different from Semi-RF as equipped with a new weighting scheme via adaptation on the current labeled data set. The proposed semi-supervised learning algorithms are practical with parameter-free settings to build an effective abbreviation identifier for identifying abbreviations automatically in clinical texts. Their effectiveness is confirmed with the better Precision and F-measure values from various experiments on real Vietnamese clinical notes. Compared to the existing solutions, our solution is novel for automatic abbreviation identification in clinical notes. Its results can lay the basis for determining the full form of each correctly identified abbreviation and then enhance the readability of the records. Keywords: Electronic medical record, Clinical note, Abbreviation identification, Semi-supervised learning, Self-training, Random forest.
Learning Dynamic Memory Network with Two Views

In this paper, we propose an end-to-end goal-oriented dialog system using dynamic memory networks with negative samples. A traditional artificial neural network learned the model using only correct answers. We improved the performance by learning the dialogue model using dynamic memory networks with negative samples for learning. After applying the negative sample, we evaluated the performance of DSTC6 track1 data up to 91.20% accuracy. On the other hand, we obtained performance decrease at track 2, 3 and 5 by applying a negative sample. We confirmed that most of this errors arise from the method of measuring sentence similarity method. Our novel learning mechanism can be easily applied to the problem of choosing the right answer among the various candidates to improve the performance.
The Velocity Tracking Problem for Navier-Stokes Flows With Boundary Control

We present some systematic approaches to the mathematical formulation and numerical approximation of the time-dependent optimal control problem of tracking the velocity for Navier--Stokes flows in a bounded, two-dimensional domain with boundary control. We study the existence of optimal solutions and derive an optimality system from which optimal solutions may be determined. We also define and analyze semidiscrete-in-time and full space-time discrete approximations of the optimality system and a gradient method for the solution of the fully discrete system. The results of some computational experiments are provided.
Upstream Partnership among Competitors when Size Matters Rapport

In several industries downstream competitors form upstream partnerships. An important rationale is that higher aggregate upstream volume might generate e¢ ciencies that reduce both xed and marginal costs. Our focus is on the latter. We show that if upstream marginal costs are decreasing in sales volume, then a partnership between downstream rivals will make them less aggressive. However, a partnership might nonetheless induce both partners and non-partners to charge lower prices. We also show that it might be better for two rms to form a partnership and compete downstream than to merge. Somewhat paradoxically, this is true if they compete ercely in the downstream market with a third rm. The reason is that a merger is de facto a commitment to set higher prices. Under aggressive competition from the third rm, the members will not want to make such a commitment when upstream marginal costs are decreasing in output. SNF Working Paper No 06/17
Universal test generation using fault tuples

A test generation tool for combinational circuits called FATGEN has been developed based on the notion of fault tuples. FATGEN can be used to simultaneously generate tests for many types of misbehavior that occur in digital systems. Individual experiments involving SSL, transistor stuck-open, path delay and bridging faults for the ISCAS85 benchmark circuits reveal an average speedup of nearly 32% and test set compaction of 60% when faults of all types are analyzed simultaneously. In addition, there is an average reduction of approximately 34% in the number of aborted faults.
TERM ASSESSMENT OF PSYCHOMOTOR DEVELOPMENT AND THE RISK OF AUTISM SPECTRUM DISORDER IN EXTREMELY PREMATURE INFANTS ! ≤ 28 GA # $ A PROSPECTIVE COHORT STUDY ! PRELIMINARY REPORT

Infants ≤28 GA are at particular risk of psychomotor and neurological developmental disorder. They also remain at a higher risk of developing autism spectrum disorder (ASD), characterized by persistent decits in communication/social interactions and restricted, repetitive behaviors, activities and interests. Monitoring their development by a team of specialists (a neurologist, psychologist, psychiatrist) allows us to make an early diagnosis and to implement appropriate therapy. Neuroimaging studies during the neonatal period may be helpful in clarifying diagnosis and prognosis. Objective: The aim of the study was to search for the interrelation between the results of neuroimaging and the neurological, psychological and psychiatric evaluation at the age of 2. Material and methods: Neonates born at ≤28 weeks between 01.06. 2013 and 31.12. 2015 and hospitalized at NICU were enrolled. We present the results of the rst 12 children who have attained 2 years of corrected age and have undergone both neuroimaging, and neurological, psychological and psychiatric assessments. Transfontanel ultrasound was performed according to general standards, MRI between 38 and 42 weeks of corrected age. Neurological examination based on the Denver scale, ASD screening with use of the STAT test and psychological DSR assessment were performed at 2 years of corrected age. Results: Median GA was 26 weeks and median weight 795 g. The ultrasound examination was normal in 9 cases (75%) and MRI in 4 (33%). Abnormalities in the cerebellum were the main additional information found in MRI as compared to US. Neurological examination was normal in 8 infants (67%), in 4 of whom neuroimaging was normal. In 4 (33%) infants the neurological examination was abnormal. Psychomotor development at an average level or above was found in seven (58%) children. In 4 of them neuroimaging was normal, whereas 3 had ventricular dilatation and haemorrhagic infarct. There were 40 Neuroimaging results, short-term assessment of psychomotor development no abnormalities within the cerebellum in this group. In the remaining 5 children (42%) psychomotor development was rated as delayed. All of them had cerebellar haemorrhage. An increased risk of ASD was observed in 4 children who developed cerebellar hemorrhage. Conclusions: 1. The use of MRI at a term-equivalent age may contribute to the prognosis of neurodevelopmental outcomes in extremely premature infants, allowing risk stratication and thus enhancing early monitoring of a child’s development and functional status 2. There is a clear tendency towards abnormal psychomotor development and positive screening for ASD to co-occur with abnormal MRI ndings in the cerebellum.
An investigation into the mechanism whereby pH affects tension in guinea‐pig ureteric smooth muscle.

1. We have altered intracellular (pHi) and extracellular pH (pHo) in the smooth muscle of guinea‐pig ureter and determined the effects on evoked phasic contractions. In order to investigate the mechanisms underlying the effects of pH alteration, intracellular Ca2+ ([Ca2+]i), pHi, electrical activity and force were measured. 2. Intracellular acidification, produced by the weak acid butyrate, application of CO2 at constant pHo or removal of weak bases, greatly increased phasic contractions. Alkalinization with weak bases or by removal of CO2 inhibited contractions. The results were similar whether Hepes or CO2‐HCO3‐buffered the solutions. 3. Phasic contractions were preceded by intracellular Ca2+ transients in the ureter. Acidification of the cytoplasm led to an increase in the amplitude of the Ca2+ transient, and alkalinization decreased its magnitude. 4. In the ureter the action potential leads to Ca2+ influx, therefore electrophysiological recordings of its configuration were made during alteration of pHi. Acidification led to the action potential duration and amplitude being increased, whereas alkalinization shortened the action potential and reduced its amplitude. 5. As the effects of acidification on the action potential resembled the effects of blocking of K+ channels, we investigated whether pHi alteration was able to alter tension when K+ channels were blocked by tetraethylammonium. Acidification was unable to potentiate force under these conditions nor did alkalinization decrease force. 6. External pH over the range 6.8‐8.0 had little or no effect on pHi, phasic contractions and [Ca2+]i. Tonic contractions were enhanced, however, when pHo was increased. 7. These data suggest that pHi alteration in the guinea‐pig ureter modulates the action potential, probably by alteration of K+ currents. Subsequent changes in [Ca2+]i and contraction then occur. A potentiating effect of acidic pH on force is not common in muscle, but may be a characteristic of the smooth muscle of the urinary tract. Changes of pHo had little effect on phasic force or pHi, but modulated tonic contractions. The possible physiological significance of these results is discussed.
Short-and Long-Term Effectiveness of a Supervised Training Program in Spirometry Use for Primary Care Professionals

Introduction: Despite the importance of spirometry, its use and quality are limited in the Primary Care setting. There are few accredited training programs that have demonstrated improvement in the quality of spirometric studies. In this paper, we analyze the shortand long-term effectiveness of a supervised training program for performing and interpreting spirometries. Methodology: Ours is an intervention study with before and after measurements. The target population included teams of physicians and nursing staff at 26 health-care centers in the area of Vigo (Galicia, Spain). The structured training program involved 2 theoretical and practical training sessions (that were 2 months apart), an intermediate period of 30 supervised spirometries performed in the respective centers and weekly e-mail exercises. Effectiveness was evaluated using exercises at the beginning (test 1) and the end (test 2) of the 1st day, 2nd day (test 3) and one year later (test 4), as well as the analysis of spirometries done in month 1, month 2 and one year later. Participants also completed a survey about their satisfaction. Results: 74 participants initiated the program; 72 completed the program, but only 45 participated in the one-year evaluation. Mean test scores were: 4.1±1.9 on test 1; 7.5±1.6 on test 2; 8.9±1.3 on test 3, and 8.8±1.4 on test 4. During month 1, the percentage of correctly done/interpreted tests was 71%, in month two it was 91% and after one year it was 83% (P<.05). Conclusions: A training program based on theoretical and practical workshops and a supervised follow-up of spirometries significantly improved the ability of Primary Care professionals to carry out and interpret spirometric testing, although the quality of the tests diminished over time. © 2012 SEPAR. Published by Elsevier España, S.L. All rights reserved. Efectividad a corto y largo plazo de un programa tutelado de formación en espirometrías para profesionales de atención primaria
SELECTION OF THE EUROPEAN CRANBERRY IN LITHUANIA / EIROPAS DZĒRVEŅU SELEKCIJA LIETUVĀ

A detailed evaluation of the morphological diversit y and economical properties of the European cranberry was carried out in 2000 – 2008 in the Kau nas Botanical Garden of Vytautas Magnus University with the purpose of ascertaining the mos t valuable clones. The European cranberry clones were selected from the strictly protected ar eas of Čepkeliai, Žuvintas, and Kamanos in 1995 – 1999. These clones with distinctive morphological peculiarities were propagated and planted into acid peat (pH 3.5 – 4.0) in the field collection of the Kaunas Botanical Garden for further investigations. The results of the comprehensive ev aluations of the phenotypic and genetic diversity of the European cranberry were crowned wi th the selection of the most valuable clones. These clones were compared with Estonian and Russia n cultivars. Berry size, yield, and the amount of biologically active substances were evaluated. T he selected clones are characteristic of exceptional biological and biochemical peculiaritie s. The five Lithuanian clones ‘Amalva‘, ‘Žuvinta‘, ‘Vaiva‘, ‘Vita, and ‘Reda‘ were proposed to recieve the cultivar status. Kopsavilkums Novērojumi par Eiropas dz ērveĦu morfoloăisko daudzveid ību un ekonomiskaj ām īpašībām tika veikti no 2000. – 2008. gadam Vitautas Magnus unive rs tātes KauĦas bot āniskajā dārzā ar mērėi noskaidrot vērtīgākos klonus. Eiropas dz ērveĦu kloni tika izraudzīti no īpaši aizsarg ājamām teritorijām Čapkeliai, Žuvintas un Kamanos, laik ā no 1995. – 1999. gadam. Šie morfolo ăiski atšėirīgie kloni tika pavairoti un iest ādīti skābā kūdrā (pH 3.5 – 4.0) t ālākai izpētei un novērojumiem kolekcijas st ādījumos KauĦas bot āniskajā dārzā. Pēc vispusīgiem pētījumiem par Eiropas dzērveĦu fenotipisko un genotipisko daudzveid ību rezult āti ir vainagojušies ar v ērtīgāko klonu izlasi. Šie kloni tika sal īdzināti ar Igaunijas un Krievijas dz ērveĦu šėirnēm. Tika vērtēts ogu lielums, raža un biolo ăiski aktīvās vielas. Izvēlētajiem kloniem bija īpaši vērtīgas bioloăiskās un bioėīmiskās īpatnības. Pieci Lietuvas kloni ‘Amalva’, ‘Žuvinta’, ‘Vai va’, ‘Vita’ and ‘Reda’ ir pieteiktas, lai sa Ħemtu šėirnes statusu.
Synthesis of 4-(4-aminophenoxy)-N-propylpicolinamide

4-(4-aminophenoxy)-N-propylpicoliamide 4 is an important intermediate for the synthesis of many biologically active compounds. The compound 4-(4-aminophenoxy)-N-propylpicolinamide was obtained by three simple steps to synthesis from picolinic acid. In this paper, three novel 3-phenyl-1H-pyrazole derivatives were prepared. The structure was confirmed by MS and 1 H NMR. Furthermore, the synthetic method was optimized. The total yield of the target product was 80%. Introduction Cancer is one of the most serious diseases that threaten human life. Fast-paced life, high pressure work and disorganized lifestyle all increase our chances of getting cancer. In the same time the changing of the environment make the kinds of cancers more complex and changeable [1-3]. Traditional cancer treatment is mainly based on surgery, radiotherapy and chemotherapy. However, Most of the cancers are not obvious in the earlier stage, absolute cure is not easy for traditional therapies, and the toxic side-effect is too harmful to recover [4-5]. In recent years, with the progress of molecular biology research, molecular targeted therapy has become a hot spot as a new biological treatment method. Compared with traditional chemotherapeutic drugs, antitumor therapy designed for specific molecular target of tumor has the advantages of strong specificity, obvious curative effect and less damage to normal tissues [6-7]. 4-chloropyridine derivatives are important intermediates for many small molecule inhibitors, all of which have good pharmacokinetic activity. There are many signaling pathways in our body that affect the growth, metastasis, proliferation and proliferation of cancer cells. Small molecule inhibitors can prevent cell growth by combining with small signaling pathways and promote cell apoptosis. Part of the highly potently and selectively small molecule inhibitors are shown in Figure 1, those compounds content the fraction of 4-(4-aminophenoxy)-N-propylpicolinamide all have great curative effect. Our synthetic 4-(4-aminophenoxy)-Npropylpicolinamide 4 derivatives are an essential integral part of many similar small molecule inhibitors. There are many reported synthesis methods, most exist in shortcomings of long synthetic route, low yield, and harmful to the environment [8-9]. To solve those problems, this study designed and optimized the synthetic route and method of 4-(4-aminophenoxy) -N-propylpicolinamide derivatives. The 4-(4-aminophenoxy)-Npropylpicolinamide 4 was synthesized from 4-chloropicolinic acid main via nucleophilic substitution reaction. Make it more suitable for industrial production. 243 Copyright © 2018, the Authors. Published by Atlantis Press. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/). Advances in Biological Sciences Research (ABSR), volume 6 2017 2nd International Conference on Biological Sciences and Technology (BST 2017)
A time sharing fluorometer for the readout of intracellular oxidation-reduction states of NADH and flavoprotein.

Cellular fluorochromes, pyridine nucleotides (PN), and flavoproteins (Fp) reflect the redox state of the cytoplasmic space and mitochondria of the intact cells and tissues and afford a direct readout of essential parameters of cell metabolism. A time sharing fluorometer which alternates every 8 msec the overlapping emission and excitation wavelengths of both fluorochromes enables nearly simultaneous recording of the two components. From a spot of several millimeters in diameter an adequate signal‐to‐noise ratio can be obtained at a response time of less than 0.1 sec. In conjunction with the regenerative flow apparatus, the fluorescence of the components can be recorded in times down to 20 msec. Applicability to reaction kinetics in perfused organs and in suspensions of mitochondria as well as to other systems with double fluorescence labels is indicated.
Factors Associated with Residential Long-Term Care Wait-List Placement in North West Ontario*

RÉSUMÉ Cet article examine les facteurs associés à l’inscription sur une liste d’attente pour une place en établissements de soins de longue durée en Ontario (Canada). L’analyse a été réalisée à partir de données collectées avec l’Instrument d’évaluation des résidents - Services à domicile (RAI-HC) dans le Réseau local d’intégration des services de santé du Nord-Ouest (RLISS) en 2014. Notre analyse quantifie l’influence de facteurs associés aux bénéficiaires de soins, aux aidants naturels et aux établissements de soins sur la probabilité d’inscription sur une liste d’attente. Nous observons que ces trois facteurs sont significativement reliés à l’inscription sur une telle liste. Les résultats de cette analyse pourraient avoir une incidence sur les politiques visant à réduire le nombre d’individus vivant dans la communauté qui sont inscrits sur une liste d’attente pour des établissements de soins de longue durée. ABSTRACT This article is based on a study that investigated factors associated with long-term care wait list placement in Ontario, Canada. We based the study’s analysis on Resident Assessment Instrument for Home Care (RAI-HC) data for 2014 in the North West Local Health Integration Network (LHIN). Our analysis quantified the contribution of three factors on the likelihood of wait list placement: (1) care recipient, (2) informal caregiver, and (3) formal system. We find that all three factors are significantly related to wait list placement. The results of this analysis could have implications for policies aimed at reducing the number of wait-listed individuals in the community.
Meta-Analysis and Inadequate Responders to Intervention

A meta-analysis by Tran, Sanchez, Arellano, and Swanson (2011) of the published RTI literature found that the magnitude of effect size (ES) between responders and low responders at posttest was significantly moderated by the pretest ES and the type of dependent measure administered, whereas no significant moderating effects were found in the mixed regression analyses for number of weeks of intervention, length of sessions, number of sessions, type of intervention (one-to-one vs. small-group instruction), and criteria for defining responders (cutoff, scores, discrepancy, benchmark). Overall, the synthesis questions whether the published evidence on RTI related to classifying responders and nonresponders at posttest has shown to be adequately separated from pretest learner characteristics. Stuebing et al. (2012) provided an excellent critique of this metaanalysis and raised at least four major issues related to interpreting the outcomes. We appreciate the opportunity to respond to these concerns.
PROCESS WEAVER: Adding Process Support to UNIX

A description is given of Process Weaver, a set of tools that adds process support capability to UNIX-based environments, including heterogeneous environments with UNIX servers and PC workstations. IT comprises languages and language-based graphical editors for describing processes from three perspectives: a project management perspective, a team-interworking perspective, and the perspective of individual team members. Process descriptions are structured into fragments that are individually enactable. Process enactment assists in managing the flow of information in project teams, provides individuals with task-specific work environments, and automates activities that can be performed without human intervention. Enactment of process descriptions may be achieved under process control, which means that Process Weaver can support process evolution in a controlled manner. Enactment is fully distributed, and takes advantage of underlying tool integration mechanisms for process control of tools. >
Aerosol optical properties over marine and continental sites of India during pre-monsoon season

Ground and satellite based measurements of spectral optical properties of aerosols have been carried out at Dehradun (DDN) in the Indo-Gangetic Plain (IGP) and Kavaratti (KVT) at Lakshadweep in southern Arabian Sea during pre-monsoon season (March– May) 2012. The measurements illustrate distinct seasonal impact on aerosol properties with maximum dust loading during May in conjunction with anthropogenic aerosols over DDN and marine aerosols over KVT. Aerosol optical depth (AOD) values have been observed maximum in May (0.72  0.03) over DDN and in April (0.77  0.05) over KVT. The high AOD at DDN during May is associated with low  and high , means higher loading in May is associated with coarse mode aerosols, may be dust loading as evident from SSA and volume size distribution. Similarly, high AOD at KVT during March and April are associated with high  and low , may be due to anthropogenic influence as evident from BT analysis as well as SSA and volume size distribution. However, influence of marine aerosols is also noticeable over KVT during May as indicated by the lower values of  with high turbidity coefficient . Comparison between sunphotometer and MODIS AOD observations indicates good statistical agreement with the minimal error.