Miracle-dz/UniFAR-FTUs huggingface dataset:
Survey of Digital Forensics Technologies and Tools for Android based Intelligent Devices

During the rapid development of mobile wireless technologies and applications, the Android operating system, due to its open-source characteristics, has become the most popular development platform in the smartphone market. Meanwhile, as Android-based intelligent mobiles devices experience a rapid increase in numbers, high-tech crimes involving such devices have become more versatile, affecting an ever increasing amount of data, thus making digital evidence an indispensable part of the evidence that needs to be seriously dealt with during crime investigations. Consequently, understanding the internal structure of Android and the various data operations in the file systems becomes necessary in Android-based digital forensics. In this paper, we survey the state-of-the-art of technologies in Android-based digital forensics and some popular tools in the aspects of data recovery and acquisition, file system analysis and data analysis. We also discuss some technical challenges and point out future research directions in Android-based digital forensics.
Sonar image processing based underwater localization method and its experimental studies

In this paper, we propose a sonar image processing based underwater localization method. P-SURO II is a sort of hybrid AUV which can be operated in both of ROV and AUV modes [1]. For this vehicle, there is a 2D BlueView sonar mounted in front of the platform for obstacle detection. This sonar also can be used for underwater localization in certain specific environments. In [2], the authors proposed a sonar aided inertial navigation method. However, in this case, they used the BVTRangeData Object [3], and therefore the algorithm was strongly restricted in certain specific environments such as water tank where we can easily abstract the line information from sonar range measurement. For more complicated environment, this method is difficult to be directly applicable. In this paper, we propose a sonar image (BVTMagImage Object [3]) processing based localization method which can be applicable to complicated underwater artificial structure environment where the structure information is known in priori. Some of water tank experimental studies are carried out to demonstrate the effectiveness of proposed localization scheme.
Fruit and vegetable intake and the metabolic syndrome.

With great interest we read the article by Esmaillzadeh et al (1). The authors performed a cross-sectional study of fruit and vegetable intake in relation to the metabolic syndrome in 486 female Iranian teachers. The authors concluded that higher intakes of fruit and vegetables are associated with a lower risk of the metabolic syndrome. Because the prevalence of the metabolic syndrome ranged from 17% to 38% across the quintiles, it is not a rare disease. Esmaillzadeh et al used corrected prevalence odds ratios derived from logistic regression using a formula suggested by Zhang and Yu (2). This method, however, may yield inaccurate estimates and 95% CIs, especially when confounding is present. The preferred statistical method for a cross-sectional study with a common outcome is to obtain the prevalence ratio by log-binomial regression (3–5), eg, by means of PROC GENMOD in SAS (6).
Current single event effects and radiation damage results for candidate spacecraft electronics

We present data on the vulnerability of a variety of candidate spacecraft electronics to proton and heavy ion induced single event effects, proton-induced damage, and total ionizing dose. Devices tested include optoelectronics, digital, analog, linear bipolar, hybrid devices, analog-to-digital converters (ADCs), digital-to-analog converters (DACs), and DC-DC converters, among others.
The Good, the Bad, and the Misguided: How Managers Inadvertently Encourage Deviant Behaviors

Executive Overview Recent estimates of the costs associated with deviant behavior in the workplace are staggering. While part of the managerial function requires the establishment of rules and policies that promote good customer service and product consistency, managers who lead with a firm hand or place too much pressure on sales quotas, may be unknowingly contributing to their employees' deviant behaviors. Managers must learn to identify the role that they play in triggering employee deviance. Once recognized, there is much that managers can do to ameliorate the triggers that encourage otherwise honest employees to engage in deviant behavior.
Fine mapping of disease genes via haplotype clustering

We propose an algorithm for analysing SNP‐based population association studies, which is a development of that introduced by Molitor et al. [2003: Am J Hum Genet 73:1368–1384]. It uses clustering of haplotypes to overcome the major limitations of many current haplotype‐based approaches. We define a between‐haplotype score that is simple, yet appears to capture much of the information about evolutionary relatedness of the haplotypes in the vicinity of a (unobserved) putative causal locus. Haplotype clusters can then be defined via a putative ancestral haplotype and a cut‐off distance. The number of an individual's two haplotypes that lie within the cluster predicts the individual's genotype at the causal locus. This predicted genotype can then be investigated for association with the phenotype of interest. We implement our approach within a Markov‐chain Monte Carlo algorithm that, in effect, searches over locations and ancestral haplotypes to identify large, case‐rich clusters. The algorithm successfully fine‐maps a causal mutation in a test analysis using real data, and achieves almost 98% accuracy in predicting the genotype at the causal locus. A simulation study indicates that the new algorithm is substantially superior to alternative approaches, and it also allows us to identify situations in which multi‐point approaches can substantially improve over single‐SNP analyses. Our algorithm runs quickly and there is scope for extension to a wide range of disease models and genomic scales. Genet. Epidemiol. 2006. © 2005 Wiley‐Liss, Inc.
Molecular cloning, characterization and analysis of the regulation of the AR02 gene, encoding chorismate synthase, of Saccharomyces cerevisiae

We describe here the cloning, characterization and analysis of the regulation of the ARO2 gene of Saccharomyces cerevisiae, the first reported study of a eukaryotic gene encoding chorismate synthase (E.C. 4.6.1.4). The gene contains an ORF of 1128 bp, encoding a protein with a calculated molecular mass of 40.8 kDa. ARO2 is regulated under the ‘general control system’ for amino acid biosynthesis by the transcriptional activator GCN4 which binds in vitro at three sites within the AR02 promoter.
Altered signalling and gene expression associated with the immune system and the inflammatory response in obesity

White adipose tissue functions not only as an energy store but also as an important endocrine organ and is involved in the regulation of many pathological processes. The obese state is characterised by a low-grade systemic inflammation, mainly a result of increased adipocyte as well as fat resident- and recruited-macrophage activity. In the past few years, various products of adipose tissue including adipokines and cytokines have been characterised and a number of pathways linking adipose tissue metabolism with the immune system have been identified. In obesity, the pro- and anti-inflammatory effects of adipokines and cytokines through intracellular signalling pathways mainly involve the nuclear factor kappa B (NF-κB) and the Jun N-terminal kinase (JNK) systems as well as the I kappa B kinase beta (IKK-β). Mitogen-activated protein kinase (MAPK) and extracellular-signal-regulated kinase (ERK) pathways, which lead to signal transducer and activator of transcription 3 (STAT3) activation, are also important in the production of pro-inflammatory cytokines. Obesity increases the expression of leptin and other cytokines, as well as some macrophage and inflammatory markers, and decreases adiponectin expression in adipose tissue. A number of cytokines, e.g. tumour necrosis factor alpha (TNF-α) and monocyte chemotactic protein 1 (MCP-1), and some pro-inflammatory interleukins, leuckocyte antigens, chemochines, surface adhesion molecules and metalloproteases are up-regulated whereas other factors are down-regulated. The present paper will focus on the molecular mechanisms linking obesity and inflammation with emphasis on the alteration of signalling and gene expression in adipose cell components.
Probing the contribution of internal cavities to the volume change of protein unfolding under pressure

The structural origin of the decrease in system volume upon protein denaturation by pressure has remained a puzzle for decades. This negative volume change upon unfolding is assumed to arise globally from more intimate interactions between the polypeptide chain and water, including electrostriction of buried charges that become exposed upon unfolding, hydration of the polypeptide backbone and amino acid side chains and elimination of packing defects and internal void volumes upon unfolding of the chain. However, the relative signs and magnitudes of each of these contributing factors have not been experimentally determined. Our laboratory has probed the fundamental basis for the volume change upon unfolding of staphylococcal nuclease (Snase) using variable solution conditions and point mutants of Snase (Royer CA et al., 1993, Biochemistry 32:5222‐5232; Frye KJ et al., 1996, Biochemistry 35:10234‐10239). Our prior results indicate that for Snase, neither electrostriction nor polar or nonpolar hydration contributes significantly to the value of the volume change of unfolding. In the present work, we investigate the pressure induced unfolding of three point mutants of Snase in which internal cavity size is altered. The experimentally determined volume changes of unfolding for the mutants suggest that loss of internal void volume upon unfolding represents the major contributing factor to the value of the volume change of Snase unfolding.
Extraction of Advertising Words from Text and Image based Spam mails for Classification

Email is a very popular way of communicating with others over the internet. As number of internet users are growing rapidly, many people are finding, email communication an inexpensive way to send their data and for the communication. Almost every website ask for email id so as to complete their registration and making users more and more prone to get affected by the spam mails. These uninvited bulk emails occupies consumes large amount of network bandwidth and it also requires server storage space. Recently, Image spam is kind of spam invented by the spammers where advertising details are specified in the image or picture files. In the proposed system the technique of extracting promotional (Advertising) words from text and image based spam is discussed.
A temperature variation compensated 60-GHz low-noise amplifier in 90-nm CMOS technology

The paper presents a RF/analog co-design methodology of designing a CMOS millimeter-wave (mm-wave) low-noise amplifier (LNA) with temperature-compensation biasing scheme. A 60-GHz LNA is designed and fabricated in a standard 90-nm bulk CMOS process. A switchable temperature-compensation bias circuitry, which allows the LNA to be tested by biased with the temperature-compensated biasing circuitry or with external voltage supply, is integrated in the LNA chip. This experiment proves that the proposed biasing scheme can significantly reduce the gain variation under different operating temperatures.
Constructing a Knowledge Base for Entertainment by Interlinking Multiple Data Sources

This paper describes a knowledge base for entertainment domains, including movies, music, and celebrities. We present an ontology model for representing graph-based knowledge, and describe knowledge processing techniques for constructing an entertainment knowledge base, which is comprised of collection and extraction of large-scale data, and knowledge transformation from them. In particular, we address entity resolution and consolidation techniques for integrating particular entities among heterogeneous data sources. We also demonstrate a mobile application using this knowledge base, which allows users to discover relevant entertainment content based on question & answer system.
Emergence of Culicoides obsoletus group species from farm‐associated habitats in Germany

Biting midges of the genus Culicoides (Diptera: Ceratopogonidae) may transmit several arboviruses to ruminant livestock. The species of the Obsoletus group are considered to be among the most important vectors of bluetongue virus (BTV) in northern Europe. As agricultural environments offer suitable habitats for the development of their immature stages, the emergence of adult Culicoides from potential breeding sites was investigated at 20 cattle farms throughout Germany in 2012 and 2013. In analyses of species‐specific habitat preferences and relationships between Culicoides abundance in breeding substrates and their physicochemical characteristics, dungheaps emerged as the most important substrate for the development of Culicoides obsoletus sensu stricto (s.s.) (Meigen), whereas Culicoides chiopterus (Meigen) and Culicoides dewulfi Goetghebuer were generally restricted to cowpats. A decreasing pH value was associated with a higher abundance or a higher probability of observing these three species. Furthermore, the abundance of C. obsoletus s.s. was positively related to increasing moisture. Dungheaps were very productive breeding sites for this species and are therefore suggested as a target for potential control measures.
Is There Any Chlorine Monoxide in the Stratosphere?

A ground-based search for stratospheric chlorine monoxide was carried out during May and October 1981 with an infrared heterodyne spectrometer in the solar absorption mode. Lines due to stratospheric nitric acid and tropospheric carbonyl sulfide were detected at about 0.2 percent absorptance levels, but the expected 0.1 percent lines of chlorine monoxide in this same region were not seen. Stratospheric chlorine monoxide is less abundant by at least a factor of 7 than is indicated by in situ measurements, and the upper limit for the integrated vertical column density of chlorine monoxide is 2.3 x 1013 molecules per square centimeter at the 95 percent confidence level. These results imply that the release of chlorofluorocarbons may be significantly less important for the destruction of stratospheric ozone than is currently thought.
Is violent method of suicide a behavioral marker of lifetime aggression?

OBJECTIVE The main purpose of this study was to investigate whether the method of suicide is a valid behavioral marker of a lifetime history of aggression. METHOD The authors applied the psychological autopsy method to investigate 310 individuals who committed suicide. They used structured clinical assessments and personality trait scales in interviews with family members of the deceased. RESULTS Violent method was associated with a higher level of lifetime aggression and a higher level of impulsivity. In addition, violent method was associated with lifetime substance abuse or dependence and psychotic disorders. Controlling for age, sex, substance disorders, and other major psychopathology, the authors found that lifetime aggression and the interaction between impulsivity and aggressive behavior remained associated with violent method. CONCLUSIONS These results support the use of violent method of suicide as a behavioral marker of a higher level of lifetime impulsive-aggressive behaviors.
Emotional Intelligence as Intervention to Organizational Health

Emotional intelligence (Ei) was found to be a useful intervention to psychological health-related outcomes, including psychological stress, job satisfaction, contextual performance, organizational citizenship behavior (OCB), anxiety, and depression. In this study, three samples (n=93, 99, and 83, respectfully) from workplace employees and management school students were investigated. The empirical findings support the research notions stated above.
Unmet health needs of uninsured adults in the United States.

CONTEXT In 1998, 33 million US adults aged 18 to 64 years lacked health insurance. Determining the unmet health needs of this population may aid efforts to improve access to care. OBJECTIVE To compare nationally representative estimates of the unmet health needs of uninsured and insured adults, particularly among persons with major health risks. DESIGN AND SETTING Random household telephone survey conducted in all 50 states and the District of Columbia through the Behavioral Risk Factor Surveillance System. PARTICIPANTS A total of 105,764 adults aged 18 to 64 years in 1997 and 117,364 in 1998, classified as long-term (>/=1 year) uninsured (9.7%), short-term (<1 year) uninsured (4.3%), or insured (86.0%). MAIN OUTCOME MEASURES Adjusted proportions of participants who could not see a physician when needed due to cost in the past year, had not had a routine checkup within 2 years, and had not received clinically indicated preventive services, compared by insurance status. RESULTS Long-term- and short-term-uninsured adults were more likely than insured adults to report that they could not see a physician when needed due to cost (26.8%, 21.7%, and 8.2%, respectively), especially among those in poor health (69.1%, 51.9%, and 21.8%) or fair health (48.8%, 42.4%, and 15.7%) (P<.001). Long-term-uninsured adults in general were much more likely than short-term-uninsured and insured adults not to have had a routine checkup in the last 2 years (42.8%, 22.3%, and 17.8%, respectively) and among smokers, obese individuals, binge drinkers, and people with hypertension, elevated cholesterol, diabetes, or human immunodeficiency virus risk factors (P<.001). Deficits in cancer screening, cardiovascular risk reduction, and diabetes care were most pronounced among long-term-uninsured adults. CONCLUSIONS In our study, long-term-uninsured adults reported much greater unmet health needs than insured adults. Providing insurance to improve access to care for long-term-uninsured adults, particularly those with major health risks, could have substantial clinical benefits. JAMA. 2000;284:2061-2069
Ultra rapid calcium events in electrically stimulated frog nerve terminals.

Fast calcium events occurring in cytoplasmic organelles after a single electrical stimulus were investigated by electron spectroscopic imaging (an electron microscope technique that reveals total calcium with high sensitivity and spatial resolution) in quick frozen presynaptic terminals of the frog neuromuscular junction. In resting preparations synaptic vesicles showed a prominent calcium signal whereas mitochondria were mostly negative and only some of the cisternae of the endoplasmic reticulum were clearly positive. In preparations quick frozen 10 ms after the application to the nerve of a single, supramaximal electric stimulus, no obvious change was observed in synaptic vesicles, while calcium levels rose to high values in the endoplasmic reticulum cisternae and in the matrix of mitochondria. Voltage-induced influx of Ca(2+) within synaptic terminals appears therefore to induce an extremely rapid uptake into selected organelles. The possible physiological role of this response is discussed.
Parental persuasive strategies in the face of daily problems in adolescent type 1 diabetes management.

OBJECTIVE The study examined (1) whether daily diabetes problems that adolescents experience were associated with parental persuasive strategies (e.g., persuading the adolescent to do more to manage diabetes), (2) whether this association was mediated through greater parental worry and lower confidence in adolescents' abilities, and (3) how parental persuasive strategies may provide corrections for subsequent blood glucose control but reduce adolescent confidence for adolescents high in self-efficacy. METHOD Adolescents with Type 1 diabetes (N = 180, ages 10.50-15.58 years) and their mothers (N = 176) and fathers (N = 139) completed diaries for 14 days reporting on problems experienced with diabetes, maternal and paternal use of persuasive strategies, and confidence in adolescents' ability to manage diabetes. Parents reported their daily worry about diabetes, adolescents reported their general self-efficacy for diabetes management, and blood glucose was downloaded from glucometers. RESULTS Across reporters, multilevel modeling revealed that parents used more persuasive strategies on days when more diabetes problems were experienced. This association was mediated through parents' greater worry and lower confidence in adolescents' ability to manage diabetes. Lagged analyses revealed that adolescents' perceptions of maternal persuasive strategies were associated with improvements in next-day blood glucose, but also with reductions in adolescents' daily confidence for those high in self-efficacy. CONCLUSIONS Parental persuasive strategies appear responsive to daily problems that adolescents experience in diabetes management. Mothers' persuasive strategies may have the dual effects of correcting blood glucose levels but reducing the more self-efficacious adolescents' confidence in their own ability to manage diabetes.
Detection of EGFR expression in patients with colorectal cancer and the therapeutic effect of cetuximab.

PURPOSE This study was designed to detect the expression of epidermal growth factor receptor (EGFR) in tumor specimens of patients with colorectal cancer (CRC); moreover, the relationship between EGFR expression and clinical factors as well as prognosis were analyzed to provide a basis for individualized treatment of CRC. METHODS This study used paraffin-embedded tumor specimens of 70 CRC patients who were treated with cetuximab. Immunohistochemistry (IHC) was used to detect the expression of EGFR in CRC tumor specimens. The patient clinical features and treatment administered were recorded and then, the therapeutic effect of cetuximab was evaluated. Progression-free survival (PFS) and overall survival (OS) were assessed. RESULTS The positive expression rate of EGFR was 64% (45/70), while 18 patients had negative expression. Twenty-two cases had weak positive expression, 15 cases positive expression and another 15 strongly positive expression. Of 70 specimens, 27 (38.6%) had high EGFR expression belonging to 20 (50%) males and 7 (23%) females (p<0.05). However, age, Karnofsky performance status (KPS), tumor site, grade of differentiation and clinical stage showed no significant difference in relation to EGFR expression (p>0.05). No patient achieved complete remission (CR), 15 (21.4%) had partial remission (PR), 12 (17.1%) were in stable state (SD) and 40 (57.1%) patients had disease progression (PD). Disease control rate (DCR) was 39.02% (16/41) in the group with low EGFR expression and 48.28% (14/29) in the group with high EGFR expression (p>0.05). CONCLUSION EGFR expression in CRC tissue is correlated with patient gender. In the group with higher EGFR expression, the effectiveness of cetuximab was significantly higher than that in the low EGFR expression group, indicating correlation between the high expression of EGFR and the short-term effect of cetuximab.