Miracle-dz/UniFAR-FTUs huggingface dataset:
Condylar form alteration on skeletal class II patients that underwent orthognathic surgery: An overview of systematic reviews

Background Bilateral sagittal split osteotomy (BSSO) is commonly considered as the surgical technique of election for the treatment of skeletal class II with mandibular hypoplasia. After orthognathic surgery, condylar resorption can occur as a surgical relapse, which may affect the temporomandibular joint. Objective: This study aimed to summarise published systematic review that assess if orthognathic surgery with mandibular advancement performed on skeletal class II patients results in condylar form alteration. Material and Methods A literature search was performed using the electronic databases PubMed, Web of Science, Cochrane Library, Embase along with several sources of grey literature. Selection Criteria: Inclusion criteria were systematic reviews published until December 2019, of skeletal class II patients aged more than 18 years old that underwent BSSO with mandibular advancement surgery. Data collection: The electronic search identified 37 publications. Four publications fulfilled the inclusion criteria and were included in this meta-analysis. Qualitative assessment of the selected studies was performed using the Assessment of Multiple Systematic Reviews – AMSTAR 2 checklist. Results Four systematic reviews were included in this review. Despite its low incidence all studies reported condylar resorption. However, there were methodological limitations in all assessed articles. Conclusions The alteration of the condylar form may be a consequence of BSSO with mandibular advancement surgery. Additional high quality prospective research assisted by 3D-imaging technology is needed to allow more definite conclusions. Key words:Evidence-based orthodontics, TMJ, Class II, mandibular advancement, malocclusion, Angle class II.
Caco-2 Cell Permeability of Flavonoids and Saponins from Gynostemma pentaphyllum: the Immortal Herb

Gynostemma pentaphyllum (the immortal herb) has been an important component of Chinese Traditional Medicine for millennia. Recent clinical studies have revealed that the plant exhibits numerous beneficial biological activities, making it of interest to the pharmaceutical industry. An extract of the herb contains over 200 individual secondary metabolites including flavonol glycosides and dammarane saponins. To focus attention on the compounds most likely to be responsible for the biological activities, this study predicts the potential oral bioavailability of nine dammarane saponins and five flavonol glycosides from G. pentaphyllum using the Caco-2 cell monolayer permeability model. Two flavonoids, 8 and 9, and four saponins, 10, 11, 12, and 14, exhibited high permeability across the monolayers. The results indicated that a higher degree of glycosylation-facilitated permeability, suggestive of active transport. This study demonstrates the utility of the Caco-2 permeability assay as a method of identifying possible bioavailable compounds from medicinal herbal extracts.
Influence of Personality Traits on English Language Performance of Secondary School Students in Oyo

The study examined the influence of personality traits on English Language performance of secondary school students in Oyo Town, Oyo State, Nigeria. Descriptive survey research design was employed in the study. The population of the study comprised all senior secondary school three (SSS 3) in Oyo. Specifically, the study targeted Senior Secondary School three (SSS 3) students from 10 secondary schools in Oyo Town. Simple random sampling technique was used to select 300 respondents from the randomly selected secondary schools in the study area. Adapted questionnaire from John and Srisava (1999) was used to determine the Personality Traits of the sampled respondents and Academic Performance Test extracted from 2017/2018 WASSCE English Language past questions was used to determine the academic performance of the students. The reliability of the instrument was ascertained using Cronbach Alpha. The personality traits scale yielded reliability coefficient values of 0.79. The data collected were analyzed using descriptive statistics of percentage and Analysis of Variance (ANOVA). The findings of the study revealed that the personality trait that is predominant among the students was openness to experience and followed by extraversion personality traits. The second finding revealed that the level of academic performance of secondary school students in English Language in Oyo town was low. It was recommended among others that teachers, parents and students should be educated on the knowledge of individual differences of which personality trait plays a major role on how one react to issues and academic activities and performance in school.
Control Parameters Tuning Based on Bayesian Optimization for Robot Trajectory Tracking

—Industrial manipulators are increasingly required to be capable of autonomously tuning their behaviour, adapting to evolving tasks. However, due to the high variability of working conditions (such as payload, motors temperature, etc.), such an adaptable behavior deﬁnition is not trivial. The aim of the paper is, therefore, to propose an approach to autonomously tune the manipulator controller on the basis of the faced task. A Bayesian optimization based algorithm is proposed to tune the controller parameters online. By the deﬁnition of a reward function (based on the required task performance), the algorithm is capable to adapt the control parameters on the basis of a trial-and-error procedure. The proposed approach has been evaluated in simulation for a trajectory tracking control problem on a 7 degrees of freedom manipulator (a Franka EMIKA robot has been considered) with uncertain dynamic model, autonomously tuning the feedback linearization control parameters and the PID trajectory control parameters ( i.e. , 25 optimization variables). Preliminary experimental tests have been also executed on a real Franka EMIKA robot.
A Kiss of Death from a Puff of Smoke: Moyamoya due to Sickle Cell Neuro-vasculopathy

Moyamoya syndrome (MMS) is a neuro-vascular complication of sickle cell disease which is characterized by progressive narrowing of the carotid arteries and the subsequent development of collateral circulation. MMS is relatively uncommon but carries significant risk of morbidity and mortality as it is associated with an increased risk of cerebrovascular events [1]. The management of MMS is difficult, particularly in patients with sickle cell disease (SCD). Further research is needed to evaluate the efficacy of available treatment modalities in improving outcomes for patients with SCD. We report the first documented paediatric case of Moyamoya syndrome in Barbados in a patient with a history of homozygous sickle cell disease (HbSS) who developed recurrent haemorrhagic cerebrovascular events which resulted in the patient’s demise.
Net-Building Behaviour of Six Hydropsyche species (Trichoptera) in Relation to Current Velocity and Distribution along the Rhône River

A longitudinal succession of species of Hydropsyche along a stream continuum is a common pattern in Palearctic as well as in Nearctic regions. Using a laboratory channel, we studied the relationship between current velocity and six Hydropsyche species distributed from small streams to large rivers in the Rhône Basin (France). Different phases of net-building behaviour were used to test the reactions of larvae to variations in current speed over a range of 4-40 cm/s. Hydropsyche angustipennis had more than 30% of its larvae wandering at the end of the experiment and was the least adapted species to the experimental conditions; the proportion of wandering larvae for the other five species was less than 10%. The largest proportion of catchnets with regular meshes occurred at velocities between 28 and 40 cm/s for the upstream species (H. siltalai and H. angustipennis) and for a species of the middle reaches of stream (H. pellucidula). Another middle-reach species (H. exocellata) had the highest proportion of catchnets with regular meshes between 8 and 40 cm/s, and for the downstream species (H. contubernalis and H. modesta), this proportion occurred at 15 cm/s. Our results suggest that the species are ordered in a downstream sequence according to their ability to spin a normal catchnet when the natural current velocity decreases. Downstream species seem to be more tolerant than upstream species to low-velocity conditions that may occur over long periods in the lower reaches of large rivers.
Analysis of Students’ Sport Attitude Levels in Vocational School of Health Care Services

This study uses method to determine the levels of sport attitude of vocational school of health students in various health departments. It is important to determine the sports attitude level of university students. Socio-demographic information form of students consisting of 8 items was created to examine the attitude of students studying in the field of exercise, sports and health, which are among the main factors of health. In the second part of the questionnaire, "Sport-Oriented Attitude Scale" was used which is composed of 28 items and 3 sub-dimensions and validity and reliability study of the scale was performed by Şenturk (2015). A total of 382 people, 25.9% male and 74.1% female participated. Results revealed that sport attitude scores of males are higher than females’, and a statistically significant difference was found (p<0.5). Participants who were 28 years old and above had higher scores than others in terms of being interested in sport (p<0.006), giving importance to sport (p<0.027) and doing sport actively (p<0.017) and there was a statistically significant difference between them. However, a statistically significant difference was observed between the individuals’ sport status, their income level, place of residence, age and gender.
Customer Traffic Distribution Analysis Based on Video Information

The map constitution task of the customer movement through the store using videoanalitics has been considered. The problem is reduced to the video stream objects detection with further tracking. It is proposed to use pre-trained CNN for object detection. The experimentally justified joint use of pre-trained networks MobileNet-SSD. For the object tracking there have been performed experiments with algorithms built into the OpenCV library: GOTURN, CSRT, KCF, BOOST, TLD, MOSSE, MedianFlow, and MIL. According to the multiple object tracking accuracy (MOTA), the MedianFlow tracker is selected. Experiments were performed using a set of video sequences containing various negative parameters confirmed the effectiveness of the selected solutions.
Combined Neural Network Model for Diagnosing Computer Incidents

The basis for making a decision on responding to computer incidentsis information about characteristics of the identified security breach, the values of which are determined during the diagnosis procedure. To reduce the time spent on determining the values of characteristics and increase the reliability of the diagnosis results, it is proposed to use machine learning methods implemented on the basis of artificial neural networks. The paper considers a combined artificial neural network as the basis of a model for diagnosing computer incidents. In this model, through the use of deep learning, the drawback of the classical multilayer perceptron associated with the need to form a massive base of training examples for the specific structure of the neural network is eliminated. The results of the experiments showed that the proposed model allows one to reduce the duration of training, while not reducing the values of the quality indicators of the functioning of the neural network.
2-Amino-4-aryl thiazole: a promising scaffold identified as a potent 5-LOX inhibitor

Human 5-lipoxygenase (5-LOX) is an important enzyme in the biosynthesis of leukotrienes and is a target for asthma and allergy treatment. Zileuton is the only drug currently marketed that targets this enzyme (IC50 ∼ 1 μM). So, the development of novel lead compounds is highly desirable. A series of 2-aryl indole, thiazolopyrazole acid, oxadiazolobenzothiophene, 1,4-disubstituted-1,2,3-triazole, 2-amino-4-aryl thiazole and 4,4′-(1,4-phenylene)bis(1,3-thiazole) derivatives when tested against this enzyme resulted in the identification of a potent compound (1d), p-fluoro substituted 2-amino-4-aryl thiazole, with an IC50 of ∼10 μM. Another lead compound identified is (4a), a thiazolopyrazole acid derivative (IC50 ∼ 40 μM). All the compounds exhibit poor DPPH radical scavenging activity which suggests that their action occurs not due to the disruption of the redox cycle of iron present in the enzyme (unlike zileuton) but through competitive inhibition, since the Vmax remains constant but the Km increases with an increase in inhibitor concentration. Molecular docking of 1d and 4a to the active site of 5-LOX also supports the experimental data, and suggests that their possible mechanism of action is through competitive inhibition. The current study identifies a promising lead molecule which could be improved further to match the activity of the commercial drug.
Intergenerational Effects of Early-Life Advantage: Lessons from a Primate Study

This paper uses three decades of studies with Rhesus monkeys to investigate the intergenerational effects of early life advantage. Monkeys and their offspring were both randomly assigned to be reared together or apart from their mothers. We document significant intergenerational effects of maternal presence. We also estimate, for the first time, the intergenerational complementarity of early life advantage, where the intergenerational effects of maternal rearing are only present for offspring that were mother-reared. This finding suggests that parenting is the primary mechanism driving the intergenerational effects. Our paper demonstrates how studies of primates can inform human development.
Scalable Schema-Guided Dialogue State Tracking

Virtual assistants such as the Google Assistant, Alexa, Siri, Cortana etc. help users accomplish tasks by providing a natural language interface to service providers (backends/APIs). Such assistants often support a large universe of third-party APIs to accomplish various tasks. Dialogue State Tracking (DST) is a core component of such assistants. It outputs the dialogue state after each user utterance, which is a summary of the entire conversation till the current turn. The dialogue state is used to invoke the APIs with appropriate parameters as specified by the user.
Do Central Banks‘ repo Transactions and Liquidity Infusions Increase Financial Stability Risks? A Case for Circular Monetary Economics

Central banks repo market operations and liquidity infusions occasion a structural liquidity mismatch in bank balance sheets and increase the dependence on central bank liquidity. This paper argues for what I term “Circular Monetary Economics”, an approach to monetary policy that seeks to green and prudentially insulate the design and implementation of liquidity and credit facilities. Circular monetary economics will lessen the probability of cross-asset contamination within financial institutions and contagion within the broader financial system, whilst simultaneously improving the transmissions from changes in the policy rate as well as macro-prudential regimes in the event of a climate or credit-driven financial shock.
DESIGN DE SERVIÇO : PROJETANDO UMA EXPERIÊNCIA GASTRONÔMICA

This article aims to present the process of developing a business model facing the food industry in the design perspective focused on user experience. To define and guide the project, this was divided into two phases: the first phase being a literature survey; and the second the development of business model driven by Guidance for Project Development (GODP). Six of the eight steps proposed by the guide were developed. During the project development were adopted methodologies of Experience Design and Service Design complementarily, enabling determine collects data and target the creation phases. Through the junction of the methods adopted, we could identify the design requirements necessary for development of a business model of a service facing the gastronomic experience, and design a service focused on the user experience.
Using distributional data to explore derivational under- markedness: a study of the event/property polysemy in nominalization

This paper proposes a corpus-based analysis of deverbal suffixed nouns in Italian displaying an ambiguity between a clear event reading (partenza ‘departure’) and a clear property reading (intelligenza ‘intelligence’). It focuses, in particular on words derived with the suffixes -nza and -zione. Three sets of syntactic contexts for words containing the two suffixes (highand low-frequency -nza words and high-frequency -zione words) were extracted from a large corpus of contemporary Italian and coded according to their semantic reading. The comparison of the three datasets, on the one side, confirms an evolution, already observed in the literature, of -nza from a typically deverbal action suffix to a typically deadjectival property suffix, and, on the other side, shows that the same ambiguity is observed with -zione nouns, although, unlike the case of -nza, in this case it remains a marginal feature. The results obtained show the interest of large-scale empirical observations for the analysis of morphological phenomena, and militate in favour of a model in which (regular) polysemy should be considered as a constituting property of derived words.
The Effectiveness of Online Messages for Promoting Smoking Cessation Resources: Predicting Nationwide Campaign Effects From Neural Responses in the EX Campaign

What are the key ingredients that make some persuasive messages resonate with audiences and elicit action, while others fail? Billions of dollars per year are put towards changing human behavior, but it is difficult to know which messages will be the most persuasive in the field. By combining novel neuroimaging techniques and large-scale online data, we examine the role of key health communication variables relevant to motivating action at scale. We exposed a sample of smokers to anti-smoking web-banner messages from a real-world campaign while measuring message-evoked brain response patterns via fMRI, and we also obtained subjective evaluations of each banner. Neural indices were derived based on: (i) message-evoked activity in specific brain regions; and (ii) spatially distributed response patterns, both selected based on prior research and theoretical considerations. Next, we connected the neural and subjective data with an independent, objective outcome of message success, which is the per-banner click-through rate in the real-world campaign. Results show that messages evoking brain responses more similar to signatures of negative emotion and vividness had lower online click-through-rates. This strategy helps to connect and integrate the rapidly growing body of knowledge about brain function with formative research and outcome evaluation of health campaigns, and could ultimately further disease prevention efforts.
Involvement of D-Loop Mutations in the Occurrence of Ovarian Carcinoma

Each cell in the body contains hundreds of mitochondria; each mitochondrion contains several DNA molecules, each carrying 37 genes that participate in the production of energy. The mitochondria are organelles that function in a semi-autonomous manner, containing their own genome and are capable of replication and transcription. They are responsible for more than 90% of cellular ATP production through the process of oxidative phosphorylation [1]. Studies on mitochondria have shown that alterations in mtDNA are closely linked to hereditary diseases, ageing and cancer [2]. Indeed, the involvement of mitochondria in apoptosis and probably in tumorigenesis has raised interest in the potential role of mtDNA mutations in the development of cancers [3].
Molecular identification of four medicinal plants using DNA barcoding approach from Chittagong, Bangladesh

Department of Biochemistry and Biotechnology, Faculty of Basic Medical and Pharmaceutical Sciences, University of Science and Technology Chittagong (USTC), Foy’s Lake, Khulshi-4202, Chittagong, Bangladesh. Genomics Research Group, Chittagong Veterinary and Animal Science University, Khulshi -4225, Chittagong, Bangladesh. Nextgen Informatics Pvt Ltd. Corresponding author: Md. Abul Kalam Azad, Department of Biochemistry and Biotechnology, Faculty of Basic Medical and Pharmaceutical Sciences, University of Science and Technology Chittagong (USTC), Foy’s Lake, Khulshi-4202, Chittagong, Bangladesh. Phone: +8801836930655, Email: akazadbtech@gmail.com.
The Influence of Facebook Brand Page on Consumer Purchase Intention with Reference to Fashion Retailing Industry

The competition in the fashion retail industry of Sri Lanka is reaching new heights due to various demands of the fashion consumers in Sri Lanka. As per the significant growth in the fashion retailing sector in Sri Lanka the marketers need to define the strategies to address their customer intentions. Especially with the rapid growth of the social networking sites especially Facebook in Sri Lanka, fashion retailers have to align their social media strategies with the online behavior of the consumers. This is study; mainly focused to understand the influence of Facebook fashion retailers’ brand page and purchase intention among the Sri Lankan Face book users. Objectives of this research were to understand the influence of engaging on Facebook brand page on purchase intention for fashion retail in Sri Lanka, therefore the researcher has investigated main construct of Perceived Usefulness (PU) and Perceived Ease of Use (PEOU) of the Facebook brand page and their relationship with both Attitude towards Brand (ATB) and Purchase Intention respectively. Finally, to see whether there is a mediating effect of Attitude towards Brand on the relationship between PU and Purchase Intention and PEOU and Purchase Intension respectively. The review is based on the theoretical rationale and supportive empirical findings. A descriptive statistical review is presented to reasoning why fashion industry is considered as a context to be examined whilst empirical evidences are presented to support the arguments. The paper concludes with research propositions to examine how Facebook Brand Page make an influence on Consumer Purchase Intention.