Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparation of combination between enamel matrix derivative (EMD) with synthetic bone graft and EMD with natural bone graft in intrabony defect treatment

Objective: To compare the clinical outcome of combination between EMD with synthetic bone graft and EMD with natural bone graft in intrabony defect treatment. Methods: Online searches have been conducted on the PubMed and Wiley website January 2009-November 2018 using the keywords "reconstructive surgical" AND "chronic periodontitis" AND "regeneration" and the keywords contained in the MeSH browser, produce 272 articles but only six articles met inclusion criteria. Result: At the six studies consisting of 119 subjects showed a decrease in probing depth (PD) and changes in clinical attachment loss (CAL) but not in gingival recession (REC), which one the combination of EMD with natural bone graft has greater than the synthetic bone graft. Conclusion: The combination of EMD with natural bone graft has more changes in PD and CAL com-pared to EMD with synthetic bone graft.
Effect of aggressive diuresis in acute heart failure with reduced and preserved ejection fraction

Heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF) had distinct haemodynamic characteristics in the setting of acute heart failure. The aim of our study is to evaluate the differential response to aggressive diuresis in HFrEF and HFpEF.
Hydrophilic and morphological aspects of films based on quaternary salts of chitosan for edible applications

Aiming to improve the homogeneity of films based on chitosan to be applied as edible coating, we carried out some chemical modifications in the polymeric structure by reductive alkylation and quaternization reactions. The resulting derivatives had different hydrophilic behaviours and cast films were characterized by wetting, swelling and topographic measurements. Concerning wetting, all samples presented similar time dependence with receding water contact angles. The quaternized chitosans were the most hydrophilic derivatives, with lower values of contact angles when compared with the parent sample. These derivatives also exhibited a higher swelling tendency. The analysis shows that the relative amount of absorbed water increases according to the length of moiety added. In general, the cast films of chitosan showed good homogeneity, displaying low roughness and regular distribution over a polar surface. On the other hand, alkyl quaternary salts showed an irregular topography with undulation and mountain‐like formation due probably to agglomeration of polymeric chains. The final film morphology was dependent on the polymer solubility, as observed by microscopic techniques. Copyright © 2010 John Wiley & Sons, Ltd.
Neutron Small Angle Scattering Studies of Micellar Growth in Mixed Anionic-Nonionic Surfactants, Sodium Dodecyl Sulfate, SDS, and Hexaethylene Glycol Monododecyl Ether, C12E6, in the Presence and Absence of Solubilized Alkane, Hexadecane

Small angle neutron scattering, SANS, has been used to investigate the structure of mixed ionic−nonionic surfactant micelles of SDS and C12E6. For solution compositions rich in C12E6, the evolution of micelle size with composition exhibits a pronounced maximum, in qualitative agreement with the theoretical predictions of Shiloach and Blankschtein [Langmuir 1998, 14, 7166], but with some important quantitative differences which are discussed. The solubilization of the alkane, hexadecane, into the mixed surfactant micelle suppresses the micelle growth with changing solution composition. For micelles rich in C12E6, hexadecane is solubilized predominantly into the palisade layer of the micelles, favoring small spherical micelles. The micellar growth with changing solution composition arises from changes in the balance between the headgroup and steric contributions to the free energy of micellization, and the addition of alkane further alters that balance in favor of small spherical micelles.
Effect of Municipal Solid Waste Compost on Mine Soils As Evaluated by Chemical, Biological And Biochemical Properties of Soil

Composts are increasingly used in land rehabilitation because they can improve soil quality and reduce the need for inorganic fertilizers. Their use contributes to an integrated approach to waste management by promoting recycling of nutrients and minimizing final disposal of organic residues that, due to their composition, can pose problems to agricultural soils. We investigated whether compost from mixed municipal solid waste (MSW) could be used to remediate two soils from a mine contaminated with trace elements. One of the soils was less acidic and had a greater content of Cu and Zn while the other had more Pb and a lower pH. The effect of MSW was evaluated by plant growth, trace element leachability, ecotoxicity of soil leachates, and biological and biochemical properties of soils. Growth of perennial ryegrass (Lolium perenne L. cv. Victorian) was stimulated in the MSW compost-amended soils compared with respective controls or with acidic soil when limed. After ryegrass had been growing for 119 days, the amount of water-extractable Zn was lower in MSW compost-amended soils, while the opposite was true for water-extractable Cu. Water-extractable Pb increased following MSW compost application to one soil and decreased in the other. The greatest dehydrogenase activity was obtained in amended limed soil, while the number of culturable bacteria and fungi and the activities of cellulase and β-glucosidase were similar in soil that was limed or following MSW compost application. In contrast, urease activity was repressed in limed or MSW compost-amended soils. Leachates from unamended soils were toxic towards Daphnia magna. Liming the very acidic soil led to a decrease in the toxicity of the leachate, but it was only in MSW compost-amended soils that ecotoxicity was no longer detected.
A novel recursive formulation for dynamic modeling and trajectory tracking control of multi-rigid-link robotic manipulators mounted on a mobile platform

This article establishes an innovative and general approach for the dynamic modeling and trajectory tracking control of a serial robotic manipulator with n-rigid links connected by revolute joints and mounted on an autonomous wheeled mobile platform. To this end, first the Gibbs–Appell formulation is applied to derive the motion equations of the mentioned robotic system in closed form. In fact, by using this dynamic method, one can eliminate the disadvantage of dealing with the Lagrange Multipliers that arise from nonholonomic system constraints. Then, based on a predictive control approach, a general recursive formulation is used to analytically obtain the kinematic control laws. This multivariable kinematic controller determines the desired values of linear and angular velocities for the mobile base and manipulator arms by minimizing a point-wise quadratic cost function for the predicted tracking errors between the current position and the reference trajectory of the system. Again, by relying on predictive control, the dynamic model of the system in state space form and the desired velocities obtained from the kinematic controller are exploited to find proper input control torques for the robotic mechanism in the presence of model uncertainties. Finally, a computer simulation is performed to demonstrate that the proposed algorithm can dynamically model and simultaneously control the trajectories of the mobile base and the end-effector of such a complicated and high-degree-of-freedom robotic system.
Impact of situational factors and electronic service quality (eServQual) on adoption of Online Grocery Shopping in Bangalore during COVID 19

This paper aims to evaluate the effect adoption of online grocery buying, by examining the “electronic service quality” (eServQual) offered by Egrocers and situational factors that affects the customers to shop groceries online during COVID 19 pandemic. Data collection was done by using structured questionnaire circulated to potential respondents who uses online platforms to shop grocery products in and around Bangalore City in Karnataka. Convenience sampling method is used and the data analysis and results of this study were based response from 164 respondents who does grocery shopping through online. The findingsshows that consumers level of familiarity towards online grocery shopping has increased. Factors like privacy, responsiveness and contact play a vital role towards consumer’s increased positive perceptions and favorable attitudes towards purchasing groceries through online medium. keywords Online grocery shopping, eServQual, situational factors, COVID 19, Bangalore. _____________________________________________________________________________________________________
Controlled synthesis of different morphologies of BaWO4 crystals through biomembrane/organic-addition supramolecule templates

By the employment of supramolecule templates composed of biomembrane and organic reagents, control over the morphologies and sizes of BaWO 4 crystals has been successfully achieved, and a series of flower-like, sphere-like, fasciculus-like, and other morphologies of BaWO 4 were obtained at room temperature. Most of the morphologies are reported for the first time. Furthermore, the control rule of supramolecule templates was also discussed. This method may satisfy the requirements of materials of various morphologies and sizes by using different supramolecule templates, and provide significant theoretical reference to the controlled synthesis of other crystals.
Effectiveness of Demonstration on Practices Regarding Hand Hygiene among Mothers of Under- Five Children in a Rural Area of Lucknow District

It has been found that washing hand with soap may prevent many common and life-threatening infections. Interventions used to prevent diarrheal diseases, includes safe drinking-water, use of improved sanitation and washing hand with soap may reduce the disease risk. The objective of the study was to assess the effectiveness of demonstration regarding hand hygiene among mothers of under-five children. Quasi experimental one group pre test post test design was used in rural area of Lucknow district with the samples of 100 mothers of under five children. Multi stage random sampling technique was used. The tools used were demographic questionnaire and checklist regarding hand hygiene. Result revealed, majority of the mothers 50% scored average and 50% scored poor in pre test whereas in post test 19% scored good 72% scored average and 9% scored poor. Mean post test score was significantly higher than the mean pre test score at the “P value” less than 0.05. The calculated t value i.e. 16.58 was compared with the tabulated value i.e 1.98 with paired t test which revealed that the demonstration administered by the investigator was found effective to increase the practice level among the mothers of under five children regarding hand hygiene.
Superior Low-Cycle Fatigue Properties of CoCrNi Compared to CoCrFeMnNi

Abstract We report on the low-cycle fatigue behavior of single-phase, face-centered cubic CoCrNi and CoCrFeMnNi at room temperature. Both alloys manifest cyclic hardening followed by softening and a near steady state until failure. CoCrNi exhibits higher strength, lower inelastic-strain, and longer lifetime than CoCrFeMnNi. For both alloys, microstructural investigations reveal no noticeable changes of texture, grain size and twin fraction. Nevertheless, CoCrNi exhibits planar dislocation structures, while CoCrFeMnNi shows well-defined wavy dislocation structures. This is due to CoCrNi lower stacking fault energy, which enhances planar slip and delays deformation localization leading to its superior fatigue resistance, compared to CoCrFeMnNi.
Structure and dynamics of water at the Pt(111) interface : molecular dynamics study

We prescribe an analytical form of the interaction potential between rigid water and a rigid platinum metal surface, which takes into account the surface symmetry and corrugation. Using this potential we perform a molecular dynamics computer simulation on water lamina restricted by two Pt(111) surfaces and investigate the structure and dynamics of water at the Pt interface. At 300 K the water layer adjacent to the metal surface displays solid‐like properties. Patches of ice‐like structure embedded in this layer are observed in the simulation. The next two layers of water display ordering similar to ice‐I. Beyond these three layers the structure and dynamics of water are bulk‐like.
Coping with changes in a sector in crisis: the case of small Spanish wineries

From a century-old artisanal way of making wines to the recent establishment of designations of origin, the wine industry in many European regions has been facing increasing demands, in a continuously changing wine environment. Today, many more wine regions are competing for consumers’ dollars, are confronting lack of generational renewal or are facing swings in wine consumption. So, how do winery operators, particularly those running small or family businesses, cope with the new developments occurring in the world of wines? The present study examines these issues from the perspective of a group of Spanish winery operators. General agreement exists regarding the opportunities that arise from the modernisation of the local wine industry, with stricter quality controls, mechanisation and other aspects facilitating the transition from making wines for household consumption to making commercial wines. Despite the gravity of current threats, most operators have planned and are implementing specific long-term strategies to maximise potential opportunities, including product quality and diversification. However, investments are very costly for many small wineries to sustain. Thus, it is argued that the wine sector and government bodies will need to intensify efforts to improve infrastructure, marketing, education and other areas to assist winery operators to confront challenges and achieve long-term survival.
Kinetic Studies on the Reactions of Hydroxyl Radicals with Cyclic Ethers and Aliphatic Diethers

Rate coefficients for the reactions of hydroxyl radicals with a series of cyclic ethers and aliphatic diethers have been determined at 298 ± 2 K. Experiments were performed using a photolytic relative rate method at atmospheric pressure and the absolute rate technique of pulsed laser photolysis−laser induced fluorescence. The temperature dependence of the rate coefficients for the cyclic ethers was also studied over the temperature range 263−372 K. The rate coefficients show significant deviations from simple structure−activity relationships. The reactivity of the aliphatic diethers toward hydroxyl radicals is discussed in terms of the initial formation of a hydrogen-bonded adduct which then undergoes an intramolecular H atom transfer via five-, six-, and seven-membered-ring structures. The reactivity of cyclic ethers is also discussed in relation to adduct formation. However, because of steric restrictions, it is unlikely that the hydrogen-bonded adducts readily undergo H atom transfer via ring formation.
Hepatocellular adenoma in the context of non-alcoholic steatohepatitis: a case report of an unusual presentation more and more frequent?

Hepatocellular adenoma (HA) is a rare benign tumor that usually occurs in the context of a young woman using oral contraception pills (OCPs), or rarely in certain inherited metabolic disorders like glycogen storage diseases, vascular hepatic disorders, and familial adenomatous polyposis. Other risk factors are not clearly established. In this unique case, we present a middle-aged man with history of nonalcoholic fatty liver disease (NAFLD), and metabolic syndrome who attend the Emergency Department for intense precordial pain, paresthesia in the left arm and diaphoresis. Ischemic heart disease was ruled out, however, during his evaluation the antecedent of a liver injury suggestive of malignancy was discovered, so it was decided to hospitalize the patient to complete his study. Laboratory data showed a slight elevation in transaminases and gamma glutamyl transpeptidase, without any other reported alteration. CT-scan reported a solid nodular lesion of 51 mm × 47 mm in segment IV LI-RAD 5 with no evidence of lymph node invasion or metastasis. A Barcelona Clinic Liver Cancer Classification Stage A hepatocellular carcinoma (HCC) was allegedly diagnosed, so it was decided to perform surgical resection. The postoperative histopathological study surprisingly showed an HA with steatohepatitis by a NAFLD Activity Score of 5 points and stage 2 periportal fibrosis. A couple of studies have reported similar findings in patients with metabolic comorbidities such as the one presented in this case. Due to the several metabolic disorders associated with NAFLD, it could represent an important risk factor for the development of HA. Studies that seek to clarify this association are necessary in the near future.
Poisson−Boltzmann Analytical Gradients for Molecular Modeling Calculations

We present the first analytical gradient Poisson−Boltzmann methodology which is routinely applicable to large biomolecular systems, such as proteins with sizes ranging from 500 to 5000 atoms. Full minimizations of several such systems in the gas phase and in solution are contrasted. Because the solvation free energy term is slowly varying with conformation, it can be evaluated infrequently in the simulation, and hence, reasonable computation times can be obtained even for large solvated systems.
Effects of Herbal Medicine Use on Adherence to Conventional Anticancer Drugs

Background: Use of herbal medicines alongside conventional anticancer drugs is common among cancer patients. This may potentially cause reduced adherence to conventional anti-cancer drugs, unpredictable side effects and unknown drug-herb interactions. This in the long run could result in poor clinical outcomes. Aim: This study was conducted to investigate how use of herbal medicines affects adherence to Original Research Article Karungi et al.; EJMP, 31(17): 1-20, 2020; Article no.EJMP. 61271 2 conventional anti-cancer drugs, to determine the proportion of patients using both conventional and herbal anticancer medicines and to identify the common herbal medicines used alongside conventional anti-cancer drugs by patients at the Mbarara Regional Referral Hospital Oncology unit. Methods and Findings: A cross-sectional study was conducted in the oncology clinic of Mbarara Regional Referral Hospital found in Mbarara district, Uganda. Data was collected between 20 March and 20 th April 2019 from 122 participants who met the inclusion criteria with subsequent consenting. Our primary outcome was adherence and secondary outcome was to investigate whether cancer patients use herbal medicines alongside conventional anti-cancer drugs. Our study had 122 patients most of them belonging to the Banyankole tribe, 75 (61.5%) being males. Of the 72 (59.02%) patients who used herbal medicine, 40 (55.56%) were males and 66.67% of the herbal users reported relief from herbal medicines. Aloe Vera was the most commonly used herb. Most of the patients 77 (63.1%) showed high adherence, this was greater in the non-herbal users than in the herbal users (COR=1.62) though this was not significant (p=0.399). Conclusion: It is most likely that majority of cancer patients use at least one herb during their course of life. The results did not show a significant relationship between herbal medicine use and adherence to conventional anti-cancer drugs. The high proportion of herbal medicine users calls for more research into the area to provide further information that can help optimize cancer treatment outcomes.
Fermented Wheat Germ Extract as a Redox Modulator: Alleviating Endotoxin-Triggered Oxidative Stress in Primary Cultured Rat Hepatocytes

Bioactive compounds such as benzoquinone derivates presented in fermented wheat germ extract (FWGE) have several positive effects on overall health status of humans and animals alike. Since available data regarding the antioxidant activity of FWGE are limited, the aim of our study was to investigate its effects on the cellular redox homeostasis applying primary hepatocyte cell cultures of rat origin. Cultures were challenged to lipopolysaccharide (LPS) treatment for 2 or 8 hours to trigger inflammatory response. Further, culture media were concomitantly supplemented with or without FWGE (Immunovet®, 0.1% and 1%). In order to monitor the metabolic activity of the cell cultures, CCK-8 test was applied, while reactive oxygen species (ROS) production was measured using Amplex Red method. Malondialdehyde concentration of culture media as a specific marker of lipid peroxidation and the activity of glutathione peroxidase in cell lysates were also determined to monitor the redox status of the cultures. Based on our findings, it can be concluded that FWGE did not show cytotoxic effects in any applied concentration in cell cultures. Furthermore, FWGE efficiently decreased cellular ROS production and lipid peroxidation rate in case of LPS-induced inflammatory response. However, without LPS treatment, higher concentration of FWGE increased the rate of both ROS and malondialdehyde synthesis. This observation may refer to the prooxidant activity of high dose FWGE, which is an important beneficial effect regarding tumor cells. However, in case of noninflamed hepatocytes, considering the results of glutathione peroxidase activity, the application of the product did not result in severe oxidative distress. In accordance with the abovementioned findings, FWGE as a redox modulator, applied in the appropriate concentration, can serve as a promising candidate in the supplementary therapy of patients suffering from various inflammatory diseases, decreasing the free radical generation, thus avoiding the occurrence of cytotoxic effects.
Percepção dos pacientes de um consultório de cardiologia acerca da utilização de plantas medicinais no tratamento da hipertensão arterial

A hipertensão arterial é uma doença crônica, com elevada incidência, baixo índice de controle efetivo e relacionada a complicações cardiovasculares importantes. As plantas medicinais podem ser uma alternativa de tratamento pouco dispendioso comparado aos fármacos sintéticos e mais acessíveis à população. Porém, é necessário que a utilização da fitoterapia não se restrinja exclusivamente ao saber popular, mas sim baseado no conhecimento científico, contribuindo assim para a inserção apropriada dessa prática na assistência à saúde. O objetivo deste estudo foi avaliar o conhecimento sobre plantas medicinais e medicamentos fitoterápicos de pacientes hipertensos atendidos em um consultório de cardiologia, na cidade de Umuarama-PR. Foi desenvolvido um estudo quantitativo e descritivo, aplicando um questionário, pelo Google Formulários, para avaliar o conhecimento sobre o assunto, com todos os pacientes hipertensos atendidos no consultório de cardiologia nos meses de agosto e setembro de 2020. Os resultados demonstraram que 47% dos pacientes conhecem alguma planta medicinal com efeito hipotensor, sendo que a transmissão do conhecimento entre as gerações configura a principal forma de aquisição da informação. Dos que utilizam alguma planta para esta finalidade, 60% perceberam efeitos positivos sobre os níveis tensionais, com baixa taxa de efeitos colaterais referidos. Considerando, de um lado, a elevada incidência de hipertensão arterial, a baixa taxa de controle eficaz dos níveis tensionais e a baixa adesão ao tratamento e, por outro lado, a vasta biodiversidade brasileira e o potencial para a produção de medicamentos fitoterápicos, o aperfeiçoamento nesta área é muito promissor.