Miracle-dz/UniFAR-FTUs huggingface dataset:
A cross-sectional study on the prevalence of work-related musculoskeletal disorders in the employees of pharmaceutical industry -

Background: Work-related musculoskeletal disorders (WRMDs) are a group of painful disorders of muscles, tendons, and nerves. Carpal tunnel syndrome, tendonitis, thoracic outlet syndrome, and tension neck syndrome are examples. Fascination with technology, overly ambitious business expectation, and neglected human factor risks can have serious effects on manufacturers, suppliers, and service enterprises. As India is one of the largest and growing hubs in the world of manufacture industry, there is a great need to identify such problem. In this study, we identified such problems and discussed it. Objectives: The aim of this study is to gather data to identify jobs or work conditions that are most problematic, using sources such as injury and illness logs, medical records, and job analyses. Materials and Methods: Data collection was done by personal interview, history and physical examinations, specific symptoms questionnaire, and rapid upper limb assessment (RULA) survey for WRMDs. Results: In our study, we found that prevalence of neck pain was highest followed by back pain in general. Most participants had complained that pain only aggravated when they continue work without taking rest. On examination, the presence of cervical spine tenderness was highest, followed by hand joints and lumbar spine tenderness. In admin and skilled participants, RULA score was up to 4 (satisfactory and modification required), but in unskilled participants, RULA was up to 7 (not satisfactory and immediate changes may require). Conclusion: Work activities which are frequent and repetitive or activities with awkward postures cause these disorders which may be painful during work or at rest. Most WRMD affects the hands, wrists, elbows, neck, and shoulders.
Diagnostic methods and emerging treatments for adult neuronal ceroid lipofuscinoses (Kufs disease)

ABSTRACT Introduction: Adult-onset neuronal ceroid lipofuscinoses (ANCL) are a group of rare inherited neurodegenerative diseases of early adulthood, named after the presence of intralysosomal autofluorescent lipopigment with characteristic ultrastructural features in neurons and other cell types. Over the last decade, six ANCL genes have been identified, three of them being related to exclusively adult-onset phenotypes, the remaining three shared with childhood-onset NCL (CNCL). Areas covered: Even in the molecular era, the contribution of neuropathological assessment is essential since genetic heterogeneity foresees new genes to be detected and validated. No disease-modifying therapy (DMT) is available for neuronal ceroid lipofuscinoses (NCL), but patients may benefit from improved symptomatic and supportive treatments, and recent advances in cellular and molecular biology (utilizing both cellular and animal models of the disease) have provided important contributions to the knowledge of NCL pathophysiology. DMT strategies aim to prevent storage formation and/or deplete accumulated substrate; few of them have already been translated into clinical practice in CNCL only. Expert opinion: The complexity of pathophysiological mechanisms underlying NCL, such as neuronal excitotoxicity, unfavourable condition of the neuropil and enhanced vulnerability of the affected cells, requires the identification of multiple targets suitable for treatments to prevent neuronal progressive dysfunction and death.
Angiographic Profile and Treadmill Test Relationship of Women with Chest Pain Suggestive of Coronary Artery Disease

Aim: The aim of present study was to analyze the prevalence and pattern of coronary artery disease (CAD) among women who underwent coronary angiography (CAG) and Treadmill Test (TMT). Methods: A total of 100 consecutive women patients for coronary angiogram were studied at Department of Cardiology, Government Medical College, Kottayam, Kerala, India on over a period of 6 months from February 2008. Total 65 women completed TMT stress test. The patients were subjected to CAG and TMT. Data were analyzed by using SPSS 20.0 software. Results: A total of 100 women patients were included. Among that 66% patients had hypertension and 47% patients had diabetes mellitus. The CAG revealed the presence of 17%, 13% and 15% of single vessel disease, double vessel disease, and triple vessel disease respectively. Vessel involvements were notably higher in positive TMT values during stress test. The sensitivity and specificity of TMT for detecting coronary artery disease in women were 61% and 69% respectively. Conclusion: It is concluded that, the findings of the present study effectively demonstrated higher predictive value of TMT in women with chest pain suggestive of CAD.
Cardiac Risk Assessment in American South Asian Population

Cardiovascular disease (CVD) includes four major areas: coronary heart disease, cerebrovascular disease, peripheral artery disease and aortic atherosclerosis, and thoracic or abdominal aortic aneurysm. CVD is the number one cause of death globally. An estimated 17.9 million people died from CVD in 2016, representing 31% of all global deaths [1]. CVDs are also the leading cause of death, hospitalizations and medical costs in United States [2,3]. An estimated 80% of CVDs are preventable [4]. Cardiac risk assessment is the cornerstone for aiding appropriate delivery of preventive therapy, and yet there are few risk models applicable to minority U.S. populations, this is particularly applicable to the South Asian sub-population.
Early findings from the evaluation of the Integrated Care and Support Pioneers in England

Purpose Integrating health and social care is a priority in England, although there is little evidence that previous initiatives have reduced hospital admissions or costs. In total, 25 Integrated Care Pioneers have been established to drive change “at scale and pace”. The early phases of the evaluation (April 2014-June 2016) aimed to identify their objectives, plans and activities, and to assess the extent to which they have overcome barriers to integration. In the longer term, the authors will assess whether integrated care leads to improved outcomes and quality of care and at what cost. The paper aims to discuss these issues. Design/methodology/approach Mixed methods involving documentary analysis, qualitative interviews and an online key informant survey. Findings Over time, there was a narrowing of the integration agenda in most Pioneers. The predominant approach was to establish community-based multi-disciplinary teams focussed on (older) people with multiple long-term conditions with extensive needs. Moving from design to delivery proved difficult, as many barriers are outside the control of local actors. There was limited evidence of service change. Research limitations/implications Because the findings relate to the early stage of the 5+ years of the Pioneer programme (2014-2019), it is not yet possible to detect changes in services or in user experiences and outcomes. Practical implications The persistence of many barriers to integration highlights the need for greater national support to remove them. Originality/value The evaluation demonstrates that implementing integrated health and social care is not a short-term process and cannot be achieved without national support in tackling persistent barriers.
The Effectiveness of Psychoeducational Group with Group Exercises Technique to Improve Student’s Self-Efficacy

Self-efficacy is a determining factor to achieve the learning objectives. Therefore, self-efficacy is important to be measured and improved. This study aimed to examine the effectiveness of a psychoeducational group with exercises techniques to improve students’ self-efficacy. This study was carried out by using a pretest-posttest control group design by involving 2 groups, the experimental and control group. The data from these groups were analyzed using repeated-measure MIX MANOVA. Meanwhile, the authors used self-efficacy scale (α=0.911) to collect the data of 14 students. The results showed that there were effects of time in the improvement of students' self-efficacy (F(2)=1,746; p<0.05), group members effect (F(3,984)=8,442; p<0.05), and the effect of time interacting with group members (F(1,293)=0.045; p<0.05). It can be concluded that the psychoeducational group with exercises techniques is effective to improve students’ self-efficacy by regarding the duration of intervention, group member, and time interaction with group members. This study implication to the guidance and counseling services will be discussed.
Macroevolution across a changing Australian landscape

Over geological time, the earth’s surface and climate have changed, rearranging continental plates and oscillating between a hothouse and snowglobe. These changes have left lasting impressions on the diversity, richness, and distribution of earth’s inhabitants. Identifying evolutionary commonalities as a result of these events is one of the main aims of the field of macroevolution. It is also the main theme which unites my thesis: investigating the influence of changes to the Australian climate and landscape on the organisms that call Australia home. Empirically, this has required extenstively sampling Australian vertebrate groups for phylogenetic, distributional, ecological, and morphological trait data. Methodologically, this has required implementing and building phylogenetic comparative methods to better understand the diversity that surrounds us. As a continent, Australia gained its independence somewhere between 40–30 million years ago when it separated from Antarctica and began drifting north towards Asia. Prior to this, the Australian plate existed alongside South America, Africa, and India, as part of the supercontinent Gondwana. In the intervening millions of years, Australia has remained isolated, and so even comparatively recent immigrant lineages have speciated in situ, resulting in a number of iconic endemic terrestrial vertebrate radiations. These radiations are great for comparative studies because they provide replicated groups which have diversified under similar environmental influences. Importantly though, they differ in absolute diversity, ecology, and behavior. My research has investigated how changes due to the isolation of the Australian plate, continental aridification, and grassland expansion have impacted the Australian fauna. In my opening chapter I discuss how the separation of Australia from Antarctica may have precipitated a mass extinction event in a relatively understudied group of lizards, the pygopodoid geckos. Next I present evidence that the Miocene aridification of Australia likely reduced the rate of phenotypic evolution of terrestrial vertebrates by facilitating allopatric speciation and niche conservatism. In the following chapter I test the hypothesis that the diversification of macropod marsupials is linked to the Plio-Pleistocene expansion of C4 grasses. Finally, I present the idea that the immense disparity in body size of Australian varanid lizards is the result of character displacement and competition occurring on a continental scale. Ultimately, the inferences we can draw about evolutionary changes occurring on deep time scales are exciting because they are often intuitive. In no place else does this seem truer than in Australia, which is a natural laboratory for macroevolutionary studies.
A stereoscopic "pickup" camera for the da Vinci surgical system

Visualization in robot-assisted minimally invasive surgery, performed with the da Vinci surgical system, is through a single stereo endoscope. The endoscope’s stereoscopic vision provides the surgeon with a sense of depth which is critical for surgery. Stereoscopic camera separation, or baseline, contributes to this perception and research in related fields has shown the benefits of an increased camera baseline. Minute surgical incisions, however, restrict current endoscopic baselines to small values. Furthermore, current clinical endoscopes have only four degrees of freedom within the surgical cavity, limiting the viewing angles provided. Restricted endoscopic movement, along with complex tumours, can make surgeries like partial nephrectomy (removal of kidney tumours) challenging. To overcome these limitations, alternate cameras have been proposed in the literature. One consistent drawback across the proposed research, however, is the lack of visual-motor alignment when working with these alternate camera views, bringing unnecessary mental strain to the surgeon. In this thesis, we present a stereoscopic “pickup” camera that has been designed to specifically address the endoscopic limitations outlined above. The camera has a special grasping interface that mates securely with a surgical instrument, and
Coordinación de coparentalidad cuando los niños y niñas se resisten o rechazan el contacto con uno de sus progenitores.

The literature on high conflict divorce has produced a large number of papers that seek to conceptualize the dynamics that lead a child to be triangulated in the conflict of adults, allied with one of the parents and rejecting the other. Less attention has been given in the literature to the interventions in these cases. This article reviews the conceptualization that has been made over the last 40 years to explain these situations. It suggests an evaluation of the factors involved following a decision tree and proposes interventions for the co-parenting coordinator, with the purpose – provided that the circumstances are appropriate – of re-establishing the child’s bond with the rejected parent.
EVALUASI FITUR WORD2VEC PADA SISTEM UJIAN ESAI ONLINE

Sampai sekarang pengembangan sistem informasi untuk mengevaluasi pemahaman siswa terhadap proses belajar memang sudah banyak dilakukan, baik berbentuk pilihan ganda maupun esai secara online. Dari referensi yang telah didapat kebanyakan menggunakan vektor kata dengan pendekatan skema pembobotan Term Frequency (TF). Dimana pada TF menghasilkan matriks kata yang senggang (Sparse), serta hasil error kemiripan yang besar. Didalam penelitian ini dievaluasi kinerja representasi fitur teks dan pembobotan yang lain, yaitu Word2vec. Selanjutnya perhitungan vektor kemiripan antar kedua teks menggunakan metode Cosine Simiarity dan Euclidean Distance. Hasil evaluasi pengujian berupa nilai koefisien antara penilaian sistem dengan penilaian manual yang dibandingkan dengan penelitian terdahulu dengan skala sama. Data yang digunakan sebanyak 2162 data. Data ini diperoleh dari 50 siswa yang menjawab 40 soal (politik, olahraga, lifestyle dan teknologi). Hasil pengujian menunjukkan rata-rata nilai precentage error dengan menggunakan fitir Word2vec sebesar 59.5%. Angka tersebut menunjukkan nilai error yang tinggi. Sehingga penelitian ini sampai pada kesimpulan bahwa menggunakan fitur Word2vec tidaklah lebih akurat pada kasus ujian esai online dibanding menggunakan fitur Term Frequency (TF).
A Comparison of Nephrotoxicity in Non–Intensive Care Unit Medical-Surgical Patients Receiving Vancomycin Alone Versus Vancomycin With Piperacillin-Tazobactam

Background Recent studies have identified an increase in nephrotoxicty in patients receiving vancomycin plus piperacillin-tazobactam (PT) when compared with vancomycin monotherapy. To date, studies have evaluated all hospitalized patients or intensive care unit patients only. The purposes of this study were to examine the incidence of acute kidney injury (AKI) in patients who received vancomycin either as monotherapy or with PT in a non–intensive care unit medical-surgical setting and to identify potential risk factors for the development of AKI. Methods A retrospective chart review was performed to identify patients who received vancomycin either as monotherapy or in combination with PT for at least 48 hours. Patients were evaluated for development of AKI, defined as serum creatinine increase of 50% from baseline. Statistical analysis included demographic, univariate, and multivariable analyses. Results One hundred eighty-nine patients met inclusion criteria. More patients in the vancomycin + PT group developed AKI than in the vancomycin monotherapy group (18.4% vs 5.6%, P = 0.008). After multivariable logistic regression of patients receiving vancomycin, PT, African American, and perioperative patients remained statistically associated with AKI. These risk factors gave odds ratios of 3.9, 3.8, and 4.0, respectively. Conclusions Patients receiving PT in addition to vancomycin were more likely to develop AKI compared with those receiving vancomycin monotherapy. African American and perioperative patients may have a higher risk.
Genetic Diversity of Colletotrichum spp. Causing Strawberry Anthracnose in Zhejiang, China.

Anthracnose is a serious fungal disease that primarily infects strawberry roots and stolons during development. Here, 91 isolates from different areas of Zhejiang province, China, were collected. Morphological characteristics were analyzed, and a phylogenetic analysis based on multiple genes (actin, internal transcribed spacer, calmodulin, glyceraldehyde-3-phosphate dehydrogenase, and chitin synthase) was performed. We found that all of the Colletotrichum species causing strawberry anthracnose belonged to the Colletotrichum gloeosporioides complex. Among them, we identified 48 isolates of C. fructicola, 21 isolates of C. siamense, 13 isolates of C. gloeosporioides, and 9 isolates of C. anenigma. C. siamense was distributed in the central and eastern regions of Zhejiang province (Hangzhou, Jinhua, Shaoxing, Ningbo, and Taizhou). This is the first report of C. siamense causing strawberry anthracnose worldwide. C. fructicola was the most dominant species causing strawberry anthracnose in Zhejiang province. We identified the four species causing strawberry anthracnose in Zhejiang province, which will improve our understanding of the strawberry anthracnose epidemic and will benefit the development of future control measures.
Two‐factor authentication using biometric based quantum operations

Two‐way authentication methods are utilized in every online user authentication transactions. Use of one time passwords (OTP) have proved to be more secure method, than one factor authentication when the two authentication schemes are carried out on different media. However, current use of OTP restricts authentication to the device itself rather than the user. The fraud cases with OTP based transactions have also increased due to growth of technology. Hence, there is a requirement of enhancing security of OTP based transactions. The study in this paper anchors on mathematically proven properties of quantum cryptography and utilizes the quantum entanglement property to generate quantum OTP (QOTP) for authenticating the user based on its biometrics. The proposed method takes into consideration various quantum computing capabilities of user, thus paving path for gradual upgradation of infrastructure. The work in the paper gives the outline of infrastructure required for implementing the proposed model and concludes by comparing security analysis of existing and proposed model against man‐in‐the‐middle attack (MITM) and user end vulnerabilities to bring forth the importance of QOTP. The practical implementation of the proposed model is envisaged as future research work due to evolving nature of quantum experiments.
Management of Cardiac Arrest in Pregnancy

Cardiopulmonary arrest, which is seemingly uncommon with an estimated incidence of 1 in 20,000 pregnant women, can occur at any time. Therefore, clinicians should be prepared to respond immediately. Maternal resuscitation is performed with only a few minor adjustments due to the anatomic and physiologic changes of pregnancy. Anesthesiologists, obstetricians and neonatologists should work as a team to ensure appropriate treatment of both mother and newborn. This review article will address the management of cardiac arrest in pregnancy and the use of perimortem cesarean delivery.
Ethical dilemmas in palliative care

The action-omission distinction The action-omission distinction highlights the difference between acting to end life and refraining from an action that may save life (failure to act). It is always morally wrong to knowingly administer a lethal injection, but withholding treatment in some circumstances may have similarly lethal effects. It might be permissible to withhold or withdraw treatment when a proposed course of treatment is so burdensome that it may not be in the patient’s best interests to continue with the treatment.
Minnesota Child Care Choices: Continuity of Care and Participation in the Child Care Assistance Program

The Minnesota Child Care Choices Research Briefs are designed to answer questions of interest to state child care administrators, county agency staff and other early childhood stakeholders. The questions they have include: How do parents make decisions about child care arrangements? What factors affect whether a family uses child care subsidies? How will Minnesota’s QRIS affect families with low incomes, particularly those eligible to receive a child care subsidy? What family, community, and child care characteristics affect child care stability and reliability, and parents’ employment outcomes?
Modeling the Distribution of Scald Type Burns in a Child

Splash or spill scald burns may be seen by medical examiners in the setting of intentional trauma or accidental injury. In order to model various scald burn scenarios, an 8-year-old subject dressed in white had colored water spilled or dropped onto her. The results were recorded by video and still photography. Five trials were performed and included: liquid in a cup thrown towards the anterior body surfaces; liquid in a cup thrown towards the posterior body surfaces; a cup of liquid spilled across a table into the lap of a seated subject; a saucepan pulled down onto the anterior torso; and a cup of liquid spilled onto the top of the head. In each of the spill and splash models described above, a large often confluent zone of staining at the site of initial liquid contact with the body was often accompanied by elongate runoff patterns following gravity; droplet staining was often noted on adjacent areas. When seated, an inverted U-shaped staining pattern was on the buttocks. Anticipation of the splash event in one trial resulted in the subject instinctively turning the anterior body away from the oncoming liquid. When presented with a scalded victim, modeling of the reported history may provide a pattern of staining that supports or refutes the explanation offered for the burn. A mobile and neurologically intact subject who can anticipate an incipient scald injury may move prior to and during contact with the liquid resulting in unique staining patterns on multiple surfaces of the body.