Miracle-dz/UniFAR-FTUs huggingface dataset:
The effects of the human oocyte vestments and follicular fluid on spermatozoa

Our knowledge of the released human ovulatory components, the cumulus-oocyte complex (COC) and follicular fluid, and their physiological effects on spermatozoa and roles in fertilisation remain poorly characterised. The aim of this study was to use a multi-pronged approach to begin to unravel these interactions and their relation to fertilisation success. Experiments designed to better replicate the physiological environment of the female tract showed environmental modulation of sperm motility. Mean sperm velocity values VSL, VAP and VCL increased by 12.4%, 15%, 16.5% respectively, when exposed to cumulus cells from pregnancy-positive donors, compared to pregnancy-negative donors. Follicular fluid elicited a [Ca2+]i response in spermatozoa that was independent of treatment outcome. The response of spermatozoa exposed to follicular fluid at a 50% (v/v) dilution was a large spike on the front of the ‘classical’ progesterone transient response, which has not been previously reported. Human sperm-zona binding (SZB) studies are hampered by the shortage of oocytes, and thus zona pellucida (ZP) available for research. As a possible source of ZP this study investigates the development of an in vitro model for oogenesis, utilising follicular fluid and cumulus cell co-culture with human embryonic stem cells. The feasibility of SPR technology, using both native and recombinant sources of ZP, to measure SZB and identify possible binding candidates is also assessed. The data in this study addresses just some of the potential effects of the COC and follicular fluid on spermatozoa. Further developments within this area may lead to better diagnostics and treatments for patients undergoing ART, in addition to providing targets for novel contraceptives.
Manejo forestal y diversidad genética de Pinus patula Schiede ex Schltdl, & Cham, en Sierra Juárez, Oaxaca

Este trabajo se enfoca en el estudio genetico de Pinus patula Schiede ex Schltdl. & Cham, la especie mas importante en el ramo forestal en Sierra Juarez, Oaxaca, con la finalidad de evaluar el efecto del manejo forestal en la diversidad genetica en sitios reforestados y de regeneracion natural. Asimismo, busca determinar si la intensa explotacion forestal de la mitad del siglo XX depaupero geneticamente a la especie en estudio. Se emplearon tres microsatelites, para seis sitios, tres bajo manejo forestal de uno, cinco y 18 anos y tres con regeneracion natural. Los resultados obtenidos de riqueza alelica (Ao = 59 y Ae = 16) y diversidad genetica (He = 0,802) fueron altos, y no existen diferencias significativas en la diversidad genetica entre sitios manejados y de regeneracion natural. Por otro lado, se encontro una estructuracion genetica intermedia segun los criterios de Wright (Fst = 0,056) entre los sitios. El analisis de agrupamiento de UPGMA sugiere que la procedencia de individuos de los sitios manejados fue de un solo sitio, Capulalpam de Mendez. En conclusion P. patula no ha sido depauperado geneticamente por manejo forestal presente o pasado y tiene caracteristicas en su historia de vida que promueven la diversidad genetica como altas tasas de entrecruzamiento. Asimismo, la alta abundancia de individuos en los sitios actua como factor amortiguador en la perdida alelica. Sin embargo, una inadecuada seleccion de arboles padre y un bajo numero efectivo de individuos pueden afectar las frecuencias alelicas estables y llevar a una perdida alelica considerable en el futuro.
Contribution of elastin and collagen to the pathogenesis of monocrotaline induced pulmonary hypertension

Male Sprague-Dawley rats were selected randomly for subcutaneous injections, 24 with monocrotaline (M) (60mg/kg) and 24 with an equivolume of saline, and studied 8, 16 or 28 days later. The right (RV) and left ventricle with septum (LV + S) were separated and weighed. The pulmonary artery (PA) was assessed by light and electron microscopy. Synthesis of elastin collagen and non-collagenous proteins was determined by measuring incorporations of /sup 3/H-valine, /sup 14/C-OH-proline and /sup 14/C-proline respectively. Total content of elastin was determined by weight of residue after CNBr digestion, and of collagen by total OH-proline content in SDS and CNBr extracts. At 16 days, the M injected rats developed a 6-fold increase in PA elastin synthesis and a 2-fold increase in medial wall thickness. Ultrastructural changes included increased microtubules and golgi apparatus in endothelium, decreased proportion of mature elastin in subendothelium and increased ground substance in media. By 28 days, M rats showed a progressive increase in PA elastin and collagen synthesis, greater than 20-fold, and in medial wall thickness, 3-fold. This was associated with a 2-fold increase in total elastin in proportion to the increase in PA weight and the development of RV hypertrophy (RV/LV + S increased moremore » than 2-fold). Progressive irreversible pulmonary hypertension induced by M may be related to continuing stimulation of PA elastin and collagen synthesis. « less
Aphelenchoides nechaleos n.sp. and A. paranechaleos n.sp. (Nematoda: Aphelenchoididae) from rice plants

Aphelenchoides nechaleos n. sp. et A. paranechaleos n. sp. provenant a l'origine de tiges de riz de Sierra Leone et du Vietnam, respectivement, sont decrits et figures. Leur aspect general et leur biologie sont tres semblables a ceux de A. besseyi Christie, 1942, mais les femelles des deux especes nouvelles ne possedent qu'un seul mucron caudal, simple, et un sac post-vulvaire plus long; les spicules sont plus robustes et comportent une extremite en crochet; le mucron terminal de la queue du mâle est semblable a celui de la femelle. Ces deux nouvelles especes sont presque identiques, ne se separant que par la forme de la queue de la femelle et la courbure des spicules
Science of the rice plant. Volume 2: Physiology.

Ce volume fait suite au premier ouvrage consacre a la morphologie du riz (1993). Il rassemble les connaissances scientifiques et techniques actuelles en matiere de riz en 6 chapitres : 1- Developpement : germination, dormance, differenciation, maturation, senescence, regulateurs de croissance. 2Nutrition et role de l'eau : rhizosphere, absorption, metabolisme des elements mineraux, besoins en eau, transpiration, resistance au manque d'eau. 3- Production de matiere seche : photosynthese, respiration, translocations, peuplement, rendement en grains. 4- Facteurs nuisibles : aleas climatiques, maladies, ennemis. 5- Accidents et troubles physiologiques : salinite, sulfates, pollution de l'air et de l'eau, pesticides. 6- Qualite du grain : proprietes physiques, chimiques et organoleptiques, stockage. Un troisieme volume sur la genetique du riz est en preparation (sortie prevue en 1996)
Ophiacantha clypeata n. sp. from the Bering Sea, with a redescription of Ophiacantha rhachophora Clark (Echinodermata: Ophiuroidea)

Ophiacantha clypeata differs from O. rhachophora in having the distal tips of the radial shields concealed, the basal upper arm plates with thorny stumps, small and inconspicuous genital slits, oral shields quadrangular and wider than long, first lateral arm shields and oral shields contiguous, not separated by the aboral plates, arm spines on the first basal segment not meeting on the aboral side of the arm segment, and entirely smooth uppermost arm spines. While the oral papillae of O. rhachophora are markedly thorny, the 6 to 10 papillae of O. clypeata are only slightly serrate. A papilla does not arise from the adoral shield in O. clypeata. Geographical distribution supports the evidence from morphological differences. While O. clypeata occurs only in the Bering Sea, O. rhachophora is apparently restricted to Japanese waters and the Eastern Sea (Clark, 1911; Matsumoto, 1917). Although the depth ranges of the 2 species overlap, O. rhachophora is found in somewhat shallower water than O. clypeata This geographical separation and the morphological differences indicate clearly that Clark's (1911) Bering Sea specimens of O. rhachophora should be separated as a distinct species.
ANALISIS RASIONALITAS PENGGUNAAN ANTIDIABETES PADA PASIEN DIABETES MELITUS TIPE 2 DI RSUD dr. SOEDIRAN MANGUN SUMARSO WONOGIRI TAHUN 2017

Diabetes Mellitus is a metabolic disorder characterized by high sugar levels. Increasing the number of DM patients shows health problems that need special attention in health services in the community. This study aims to determine the description of therapy and the accuracy of drug delivery type 2 DM in inpatient installation at Regional Hospital dr. Soediran Mangun Sumarso period January - December 2017. This research uses non experimental descriptive method with retrospective data collection. The study was conducted by looking at the description of the use of antidiabetes and analyzing it using the guidelines of Consensus Control and Prevention of Diabetes Mellitus Type 2 in Indonesia (PERKENI 2015), Practical Guidelines for Insulin Therapy in Diabetes Mellitus Patients (PAPDI 2011), and American Diabetes Association Guideline (ADA 2017). The results of 89 patients receiving antidiabetes included (64.05%) single drug and (35.95%) combination. Single drugs include sulfonylurea (1.12%), biguanid (7.86%), and insulin (55.07%). Insulin is the most widely used insulin short acting is novorapid (32.58%). Antidiabetic treatment in patients with type 2 diabetes is 100% according to FRS in Regional Hospital dr. Soediran Mangun Sumarso. Rationality based on PERKENI 2015 is 100% precise indication, 100% right medicine, 98,88% right patient, 23,60% right dose. Based on 100% precise ADA indication, 100% proper medicine, 98.88% exact patient, 100% right dose. Based on PAPDI 2011 71.91% exact dose. Keywords: antidiabetic drugs, diabetes mellitus type 2, dr Soediran Mangun Sumarso Regional Hospital of Wonogiri, rational
Metabolitos secundarios y actividad antibacteriana in vitro de extractos de hojas de Anacardium occidentale L. (marañón)

Introduction: the leaves of Anacardium occidentale L. (cashew tree) have optimal contents of nutrients and have been used as antidiarrheal and nutraceutical in animals; however, the phytochemical characterization and antimicrobial of the extracts are insufficient. Objective: to determine secondary metabolites and in vitro antimicrobial activity of Anacardium occidentale L. leaf extracts. Methods: fluid extract and 20% tincture were initially obtained from powdered leaves of Anacardium occidentale L. Phytochemical screening and quality testing of pharmaceuticals were performed. The antibacterial activity was determined (Escherichia coli, Staphylococcus aureus Bacillus subtilis, Salmonella enteric and Shigella sp.) in three dilutions of the dry extract (50, 100, and 200 mg/mL) from the 20 %, tincture and from the n-hexane, chloroform and ethyl acetate extracts (Escherichia coli, Staphylococcus aureus, Shigella sp., Salmonella enteric, Pseudomonas aerugiosa and Enterobacter aerogenes), with subsequent phytochemical characterization. Results: high content of coumarins and other metabolites such as saponins, flavonoids, reducing sugars, free aminoacids, triterpenes and/or steroids, phenols and/or tannins were detected in the fluid extract and the 20 % tincture. The refractive index, the density, the pH and the total solids showed similar results for the fluid extract and for the 20 % tincture. Besides, no significant differences were found in these parameters six months after the study. The dry extract showed antibacterial activity against Staphylococcus aureus, with the largest inhibition zones for dilution of 200 mg/mL. Furthermore, the ethyl acetate extract indicated the slowest growth of this bacterial pathogen, according to inhibition hales. In the chloroform and ethyl acetate extracts, abundant coumarins and reducing sugars were found. Conclusions: the fluid extract and the 20% tincture from Anacardium occidentale leaves contained mostly coumarins and their quality remained the same six months afterwards. N-hexane, chloroform and ethyl acetate extracts disclosed staphylococcal activity in vitro whereas reducing sugars and coumarins were detected in the last two extracts.
Some anticancer medicinal plants of foreign origin

An attempt has been made to review some medicinal plants used for the prevention and treatment of cancer in foreign countries. Information on the botanical names of plants with family names, parts used and their main active components, and original/native place of these plants have been collected from the literature. This article considers 62 medicinal plants of foreign origin. These plants belong to 40 families, and their different parts (root, stem, bark, corm, bulb, leaf, fruit and seed) or the whole plants/herbs are used. The extracts or decoctions of these are generally used. The medicinal plants contain several phytochemicals such as vitamins (A, C, E, K), carotenoids, terpenoids, flavonoids, polyphenols, alkaloids, tannins, saponins, enzymes, minerals, etc. These phytochemicals possess antioxidant activities, which prevent or can be used in the treatment of many diseases, including cancer. Herbal drugs are also known to have good immunomodulatory properties. These act by stimulating both non-specific and specific immunity.
Cytryniec chiński (Schisandra chinensis (Turcz.) Baill.) - z tradycyjnej medycyny chińskiej do współczesnej fitoterapii

Streszczenie W pracy przedstawiono charakterystykę botaniczno-chemiczno-farmakologiczną gatunku Schisandra chinensis (cytryniec chiński). Owoce S. chinensis są cennym surowcem leczniczym znanym we współczesnej fitoterapii z tradycyjnej medycyny chińskiej. Gatunek ten zaledwie przed dziesięciu laty został wprowadzony do oficjalnego lecznictwa europejskiego, w tym polskiego. Ekstrakt z owoców S. chinensis wykazuje m.in. działanie hepatoprotekcyjne, adaptogenne i ergogeniczne, przeciwnowotworowe, przeciwzapalne, przeciwwrzodowe, antyoksydacyjne i detoksykacyjne. Cenne właściwości biologiczne i wynikające z nich aplikacje terapeutyczne są uwarunkowane unikalnym składem chemicznym S. chinensis. W pracy scharakteryzowano specyficzną dla tego gatunku, grupę metabolitów wtórnych lignany dibenzocyklooktadienowe. Przedstawione informacje wzbogacono o przykłady wykorzystania ekstraktów z owoców w lecznictwie i zasygnalizowano ich zastosowanie w kosmetologii.
Public versus expert opinions regarding public involvement processes used in resource and wildlife management

Successful public involvement efforts can reduce conflict and build trust between resource managers and the public. Differences of opinion between the public and wildlife managers regarding the importance of various characteristics and methods of public involvement have implications for managers wishing to design effective public involvement processes. We compared and contrasted the preferences of German public and European experts in large mammal management regarding characteristics and methods of public involvement. Expert participants attributed high levels of importance to including scientific information in decision making while general public respondents attributed high levels of importance to the cost effectiveness and representativeness of the public involvement effort. Differences were also observed regarding public involvement methods. Experts preferred task forces and advisory groups while the general public preferred information materials and public meetings. We discuss the likely causes of similarities and differences between these two groups and examine the consequent implications for managers.
PLANT-PARASITIC NEMATODES ASSOCIATED WITH HYBRID BERMUDAGRASS AND CREEPING BENTGRASS PUTTING GREENS IN ALABAMA

Se condujo un censo para determinar los generos de nematodos fitoparAsitos mAs comunmente asociados con los hibridos del pasto bermuda ( Cynodon dactylon ? C. transvaalensis ) y el pasto rastreo bent ( Agrostis palustris ) cultivados como putting greens en los campos de golf de Alabama, e identificar los niveles de infestacion. Muestras de suelos se colectaron de putting greens cultivados con 1-3 hibridos de pasto bermuda o del pasto rastrero bent en 70 campos de golf. Nueve generos de nematodos fitopArasitos se identificaron en 157 putting greens de pasto bermuda de 70 campos de golf. Mesocriconema, Helicotylenchus, Hoplolaimus, Meloidogyne, Tylenchorhynchus, Hemicycliophora, Belonolaimus, Paratrichodorus, y Pratylenchus spp. se encontraron en 96, 61, 46, 37, 23, 21, 9, 5 y 2% de los campos y en 80, 39, 31, 16, 10, 10, 4, 2 y 1% de los putting greens censados, respectivamente. Densidades poblacionales por encima de los niveles del umbral de accion para aplicacion de nematicida se encontraron en cinco putting greens infestados con Hoplolaimus y solamente en uno por cada uno de los siguientes generos: Helicotylenchus , Hemicycliophora , y Belonolaimus. Cinco generos de nematofos fitoparAsitos se identificaron en 36 putting greens de pasto bent en 13 campos de golf. Helicotylenchus, Mesocriconema, Tylenchorhynchus, Hoplolaimus y Meloidogyne spp. se encontraron en 77, 69, 46, 15, y 8% de los campos censados y en 56, 53, 28, 11, y 6% de putting greens muestreados respectivamente. Densidades poblacionales por encima de los niveles del umbral de accion se observaron en dos putting greens para Helicotylenchus y en uno para Tylenchorhynchus.
EFFECT OF FORCE-FEEDING ONFATTY LIVER AND SERUM BIOCHEMICAL PARAMETERS IN MULE DUCKS

A study on the changes of body weight, liver and blood serum biochemical parameters - L-aspartat-2-oxoglutarat aminotransferase, alanine aminotransferase, alkaline phosphatase, �� -glutamyltransferase, total cholesterol, triglycerides and creatinine of male and female mule ducks before and after force-feeding was carried out. The forcefeeding of ducks with maize was taken after 74-days of age and continued 13 days. During force-feeding period, the body weight increased with 47.25% in males (from 3983±133.85 g to 5865±212.33 g) and with 38.06% in female ducks (from 3450±215.06 g to 4763±87.73 g). The liver weight increased 7.53 times in males (from 82±5.40 g to 600±22.86 g) and 5.65 times in females (from 77±4.81 g to 435±46.79 g). After 13 days of force-feeding significantly increased the blood serum concentration of alanine aminotransferase (P<0.05 in males and P<0.01 in females), total cholesterol (P<0.001 in both sexes) and triglycerides (P<0.001 in both sexes), and decreased of �� -glutamyltransferase (P<0.01 in males and P<0.05 in females), and creatinine (P<0.01 in males and P<0.001 in females).
The relationship between yellowhammer breeding performance, arthropod abundance and insecticide applications on arable farmland

Summary 1 The UK population of yellowhammers has declined since the mid-1980s. Concurrent increases in the use of pesticides are believed to have reduced the availability of food resources for farmland birds, including yellowhammers. To mitigate the consequences of insecticide applications on yellowhammer productivity, the relationships between insecticide application, arthropod food abundance and breeding success require quantification. 2 We studied nesting yellowhammers on a lowland arable farm in North Yorkshire between 2001 and 2003, to examine the effects of food abundance on breeding success and the effects of insecticide on food abundance. Arthropod abundances around individual nests were sampled and the timing and location of insecticide applications were recorded. 3 Nestling condition and mass on day 6 after hatching were positively correlated with the abundance of arthropods important in the diet of nestling yellowhammers. Greater mean body mass and condition corresponded with a lower incidence of brood reduction. 4 The abundance of arthropods important in the diet of nestling yellowhammers increased between mid-May and the end of July. However, arthropod samples collected within 20 days of an insecticide application did not show this seasonal increase in abundance and were depressed at levels likely to affect yellowhammer breeding performance adversely. 5 Synthesis and applications. We have demonstrated how insecticide applications can depress yellowhammer breeding productivity. We provide the requisite data for a framework that enables predictions to be made about the probable population effects of particular pesticide products. If the risk of indirect effects can be predicted accurately then appropriate mitigation and compensation measures could be incorporated into pesticide regulatory procedures and/or agri-environment schemes.
The effects of potential dietary prebiotics and grain particle size on the growth performance and intestinal microflora of young poultry

Two experiments were conducted to evaluate the effects of large particle corn, whole sorghum, and Grobiotic (GB) in a corn-soybean meal (SBM) diet with or without the addition of distillers dried grains with solubles (DDGS). The first experiment evaluated diets containing fine ground corn, large ground corn, and 20% whole sorghum with or without the addition of 15% DDGS. The second experiment evaluated diets containing fine ground corn, large ground corn, large ground corn + 5% GB, and fine or large ground corn plus 15% DDGS and 5% GB. Weight gain (Experiment 1) and feed efficiency (Experiment 1 and 2) were decreased (P < 0.05) during the first week for chicks fed the diets containing large ground corn or 20% whole sorghum in a corn-SBM diet (no DDGS), but these results did not persist in commercial broiler chicks throughout the remainder of the 21 d experiment. When 15% DDGS was included in the diet this depression in growth was not seen. In the second experiment, weight gain was increased (P < 0.05) after the first week for chicks fed diets containing 5% GB and 15% DDGS when compared to their respective controls. In Experiment 1, the diet containing 20% whole sorghum yielded the highest MEn value (P < 0.05) at both age periods when compared to all other treatments. In Experiment 2, all diets containing 5% GB yielded significantly higher MEn values (P < 0.05) at 7 d when compared to diets containing no GB. The effects of diet on AA digestibility were generally small and inconsistent in both experiments. In Experiment 1, chicks fed the large ground corn or whole sorghum had significantly increased (P < 0.05) relative gizzard weights