Miracle-dz/UniFAR-FTUs huggingface dataset:
Developmental outcome measures in neonatal physiotherapy services of the United Kingdom: a survey of current use, and facilitators and barriers to their implementation

9 Background and purpose: Current guidelines recognise the need for neonatal 10 physiotherapists to provide surveillance assessments to neonates, from birth onwards. This 11 study explored the current use, barriers and facilitators to using developmental outcomes 12 measures in neonatal units, in the United Kingdom. 13 14 Method: A cross-sectional, web-based survey with 32 items was piloted and distributed to 15 members of the Association of Paediatric Chartered Physiotherapists and advertised on 16 social media and professional discussion forums. Responses from the group of therapists 17 who reported using outcome measures, were compared with those who reported not using 18 them, using Mann-Whitney U tests for non-parametric data. Other findings were presented 19 descriptively. 20 21 Results: Forty-three completed surveys were analysed. Most respondents (91%) had a 22 positive attitude towards the use of developmental outcome measures, and many (79%) 23 used them in their neonatal practice. These included the General Movement Assessment 24 (n=18/34), Hammersmith Neonatal Neurological Examination (n=16/34), and Lacey 25 Assessment of Preterm Infants (n=15/34). The high cost of acquiring certain measures was 26 a perceived barrier (86%). The presence of a neonatal-specialist physiotherapist (p=0.023), 27 active engagement in continuous professional development (0.011) and support from fellow 28 physiotherapists (p<0.001) significantly influenced outcome measure utilisation. Conclusion: Outcome measures were commonly used in the analysed units. Perceived utility and positive attitudes towards outcome measure use are in-line with current
Evaluating iron deficiency anaemia in the third trimester of pregnancy with haematological parameters and serum ferritin concentration

Background: Iron deficiency is the commonest cause of anaemia and at least half of anaemia cases will have causes other than iron deficiency. The objective of this study was to determine the prevalence of iron deficiency anaemia among antenatal mothers based on haematological parameters and serum ferritin levels.Methods: This was a hospital based cross sectional study, conducted at Meenakshi Medical College and Research Institute, Kancheepuram from January 2017 to June 2018. Two hundred antenatal mothers who were diagnosed with anaemia in the third trimester of pregnancy were evaluated by haematological parameters and serum ferritin assay.Results: 38% of women had mild anaemia, 50% had moderate anaemia and 12% had severe anaemia. On peripheral smear, 60% had microcytic hypochromic anaemia indicating iron deficiency, and 12% had megaloblastic anaemia. In 41% of cases, the mean corpuscular volume was <82fL indicative of iron deficiency. Among the 120 women diagnosed with iron deficiency anaemia on smear, the mean ferritin level was 16.62±73.42 (less than 30µg/l). There was a statistically significant low levels of serum ferritin levels in those diagnosed with iron deficiency anaemia (P < 0.05). The serum ferritin level was >160µg/lit in 19% of cases.Conclusions: Based on the haematological parameters and serum ferritin estimation, in 60% of cases, anaemia was due to iron deficiency. Before initiating treatment, it is important to differentiate various types of anaemia, so that appropriate treatment can be given.
The coordination of breathing and swallowing across the human lifespan : implications for neural control.

Our understanding of the neural control of breathin g-swallowing coordination (BSC) is largely unclear. Although brainstem control is undo ubtedly predominant, this research investigated the hypothesis that the cortex becomes increasingly influential in BSC between birth and adulthood. The main paradigm used to test his primary hypothesis was a comparison of BSC in conditions along a continuum o f v litional through non-volitional swallowing on the basis of a decreasing level of co rti al activation along this continuum. Voluntarily-initiated swallows during wakefulness w ere at one end of the continuum and reflexively-initiated swallows during sleep were at the other extreme. Non-volitional wakeful swallows were considered between these two conditio s. The BSC of ten infants between birth and 1 year of age and twenty adults between the ages of 20 and 75 years was recorded using non-invasive tim -locked recording methods. In order to apply the ‘continuum-of-volition’ paradigm to swall owing conditions in infants, BSC was monitored during nutritive (breastor bottle-feedi ng), non-nutritive wake, and sleep swallows. Infants were monitored longitudinally to determine whether maturation of the cortex and corticobulbar tracts during the first year of life nfluenced the patterns of BSC. In adults, BSC was monitored during three non-nutritive conditions : volitional, spontaneous wake, and sleep conditions. Post-swallow expiration was found to be predominant in all conditions for all participants at all ages. In addition, the infant results revealed that nutritive BSC matured during the first year of life and differed to non-nutritive wakeful BSC, particularly in the first 2 months of life. Non-nutritive wakeful and sleep BSC did not d iffer from one another. In summary, the infant results support increasing cortical input in to volitional nutritive BSC, an early impact of feeding on BSC, and no difference between BSC when asleep and non-volitional nonnutritive swallows when awake. The results obtained from adults revealed that irrespective of the level of arousal, volitional BSC is different t o non-volitional BSC. These results imply that cortical influence on BSC is limited to condit ions in which swallowing is voluntarily initiated.
Delayed Extensive White Matter Injury Caused by a Subdural Hemorrhage and Role of Corticospinal Tract Integrity

• A subdural hemorrhage (SDH) is a common neurological disease with benign outcome. • Delayed extensive white matter injury of SDH was described in this case. • The corticospinal tract integrity assessed by diffusion tensor imaging would be useful for SDH. • Physicians should be aware of a possible delayed effect in treatment of SDH. Brain Neurorehabil. 2019 Sep;12(2):e15 https://doi.org/10.12786/bn.2019. 12.e15 pISSN 1976-8753·eISSN 2383-9910
VITAMIN C PREVENTS STRESS INDUCED CARDIOMYOPATHY IN PRENATAL NOISE EXPOSED RODENTS

Potency of oral vitamin C to prevent cardiomyopathy in prenatal noise exposed newborn Wistar rats was studied by comparing the cardiomyocyte numbers and the extracellular matrix expressions (ECM) to controls. Twenty-four newborns (NR) of 32 pregnant mothers were divided equally into 4 groups: K1 (distilled water [DW]), K2 (150 mg/kg of BW oral vitamin C once daily [VC]), P1 (4 hours daily of white noise at 95 dB [WN]+DW), and P2 (WN+VC). VC and WN were given from D1 till birth and from D15 till birth, respectively. The hearts of NR were harvested, and processed for histology slides (2 midsagittal 4 μ cut slides/ animal) stained with hematoxyllin-eosin and Masson trichrome for the cardiomyocytes and ECM quantification at the ventricles using Image Raster 3.0 and ImageJ, respectively. Pictures from 8 visual fields/ slide were taken and analyzed in duplicate (400x magnifications under a light microscope). Data were analyzed using SPSS 17; significance level of p<0.05. In P1, the cardiomyocite cell numbers was significantly lowest (p<0.001); whilst the ECM was significantly highest than K1, K2, P2 (p<0.001 and p<0.005, respectively). Here, vitamin C could prevent the adverse effect of prenatal noise exposures in the ventricle myocardium of newborn rats. Keywords: cardiomyopathy, hypertrophy, prenatal noise, vitamin C
Svårigheten med utsättning av protonpumpshämmare

Ar 2011 utlamnades recept pa PPI-preparat (protonpumpshammare) till 790 000 personer i Sverige, varav 59 % var kvinnor. Omeprazol (Losec®) ar det preparat som helt dominerar forskrivningen. Den for .
A retrospective study on middle ear risk indices in analysing the postoperative outcome following tympanoplasty

Background: Otitis media is an important and a highly prevalent disease of the middle ear and poses serious health problem worldwide especially in developing countries where large percentage of the population lack specialized medical care. A normally functioning eustachian tube is an equally essential physiologic requirement for a healthy middle ear and normal hearing. In this study we have used the middle ear risk index (MERI) developed by Kartush which generates a numeric indicator of the severity of the middle ear disease to stratify patient groups according to the severity of the disease and to evaluate the efficiency of MERI score in predicting the outcome of tympanoplasty.Methods: Patients who came and got operated for tympanoplasty to the ENT Department in Konaseema Institute of Medical Sciences and RF, Amalapuram during the study period of February 2017 to February 2018. Results: In this study graft was accepted in 22 patients (88%) and rejected in 3 (12%) patients. In patients in the mild MERI risk group n=22, graft was accepted in 21 (95%) patients and rejected in 1 patient (5%). Patient had a residual perforation. In patients in the moderate MERI risk group n=2, graft was accepted in 1 (50%) patients and rejected in 1 patient (50%). In severe risk group none of the grafts were accepted (100%). Conclusions: MERI index is in fact a very useful and honest predictor of the graft uptake and audiological gain in patients undergoing tympanoplasty surgeries for CSOM. Lower the MERI index better the outcome. Positive Belluci criteria were also found to be inversely associated with the graft uptake.
A case of potentially lethal vascular variation in association with palmaris profundus muscle

Arterial variations in upper limbs are often reported commonly. Superficial arterial variations accounting for 4.2% of all arterial variations are hazardous during any invasive procedures of the upper limb, from routine intravenous injections to surgeries. Arterial variations are usually associated with inverted or absent palmaris longus. Palmaris profundus, a rare anomalous variation of palmaris longus has been reported in carpal tunnel syndrome as its tendon was associated with median nerve in the carpal tunnel. The authors reported a unique variation in the upper limb arterial pattern—the presence of bilateral superficial brachioulnar artery associated with unilateral palmaris profundus muscle and an abnormal radicle of musculocutaneous nerve to the median nerve in the left side.
Resistant Staphylococcus aureus infections in the United States: A new classification, a new resistance and the implications for surveillance, prevention, and control

Methicillin-resistant Staphylococcus aureus (MRSA) infections are often defined as healthcare-associated (HA) or community-associated (CA) based on three different classification schemes: healthcare risk factor, infection type, or susceptibility pattern. This dissertation analyzed the sensitivity, specificity, and utility of these classifications using MRSA case data from Michigan. MRSA infections were voluntarily reported to the Michigan Department of Community Health (MDCH) from October 2004 through December 2005. Data on patient demographics, risk factors, and infection information were recorded on the MDCH MRSA Report Form and submitted with laboratory susceptibility test results. A total of 2,151 non-duplicate MRSA infections were reported. Pulsed-field gel electrophoresis (PFGE) tests were conducted on 244 randomly selected isolates from reported cases. The first project classified MRSA infections as HA or CA using each of the three classification schemes, then examined results for inconsistency across methods. Comparison of HA and CA results using the common classification schemes revealed a large proportion of inconsistent results. The second project used PFGE test result as a gold standard to consider the three classification schemes and other important contributing variables aimed at producing an improved multivariable classification model. This new model using infection type, susceptibility pattern, age and hospitalized as variables better predicted PFGE classification of HA or CA than any other single
Enhancing Board Effectiveness: What About Induction and Training Programs for Directors?

The paper discusses the idea that an institutionalized and effective board induction and training process could maximize the director’s contribution and thus improve board effectiveness in banks, especially if training and induction are done in a board that respects good practices with regards to board independence, board diversity, presence of board committees, degree of directors’ turnover, recommended by regulators and institutions. In the wake of the recent financial crisis, in fact, a growing “professionalisation” of directors may be considered as a tool to improve the board effectiveness in banks. Contrary to the relevance of the topic, the available literature is very poor. Using the qualitative research methods, the paper shows, first of all, the state of the art on board induction and training programs for directors in the 25 largest European banks and, then, the results of a survey about the opinions of an Italian panel on the topic. Findings confirm that induction and training programs for directors are a fundamental tool to improve the effectiveness of corporate governance. However there is a substantially limited dissemination of these practices in banks and, in those cases where these practices are used more extensively, it is possible to spot some areas of improvement compared to best practices. Overall, the most disappointing results, in terms of the dissemination of induction and training programs for directors, emerge from the interviews carried out on the Italian panel. Based on the results, some motivation and managerial implications are proposed.
Antitumoral Effects of Metformin in Ovarian Cancer

In the last years, the antidiabetic drug metformin has received considerable attention in pursuing new drugs for anticancer treatments. Several reports have shown that metformin would have antitumor effects, not only attributable to its systemic effects but also due to direct effects on tumor cells. It has been proposed that metformin could be a suitable alternative for the treatment of gynecological cancers, such as ovarian cancer. This disease is characterized by high cell proliferation and angiogenesis potential, because ovarian cancer cells overexpress most oncogenic molecules including growth factors. The aim of the present chapter is to discuss the molecular mechanism by which metformin would affect tumor cells, with focus on epithelial ovarian cancer.
SAT, a New Approach in Understanding and Treatment of Subclinical Endometritis in Dairy Cows

The aim of this work was to compare the use of local intrauterine moist heat infusion to intrauterine antibiotics infusion, for treatment of subclinical endometritis which affects reproduction and milk production. 42 repeat breeder cows were divided into 4 groups, group 1 was the untreated control (=10 cows). Group 2 (=10 cows) was treated by 50 ml of Oxytetracycline 5% intrauterine for three successive weeks. Group 3 (=10 cows) intrauterine infusion with 30 ml saline adding to them 10 ml Gentamycin 10% and 10 ml penicillin and streptomycin for three successive weeks. Group 4 (=12 cows) intrauterine infusion with 50 ml sterile boiling water (≈100°C) was applied directly to the uterus for only one time. Leukogram was done before and after treatment, it showed leukocytosis and neutrophilia in all the study groups. After treatment for 36 hours and one week, there were no significant changes in the leukogram results of groups 1, 2 and 3. While in Group 4 showed decreasing in numbers of leukocytes (11.92 ± 0.75) and neutrophils (0.87 ± 0.16) to its normal limits after 36 hours and one-week post-treatment. Our new method gave the highest cumulative pregnancy rate 83.3% while other groups using antibiotics or antibiotics with saline gave lower pregnancy rate 40% and 50% respectively (P > 0.001). We named this new treatment method “Samia-treat; SAT”. SAT is a whole new and effective treatment for cases of repeat breeder which are caused by SCE in dairy cows; it caused increase in reproductive performance and cumulative pregnancy rate without over use of antibiotics.
Invasive Breast Cancer in Malmö 1961-1992. An epidemiological study.

In the present thesis incidence, survival, mortality, cure and prognosis in invasive breast cancer in Malmo was studied over a 30 year period. Validated data from the Cancer Registry and the Cause of Death Registry were used. In the process of validation systematical biases were identified in both registers. The incidence increased over time and was strongly related to increases in diagnostic activity, especially mammographic screening. Therefore, comparisons of incidence between populations with differing diagnostic activity is of little informative value. There was a statistically significant decrease of 43% (95% CI:26%-56%) in breast cancer specific mortality 1976-1992. In the remainder of Sweden the decrease for that period was 12% (95% CI: 8%-16%). The decrease was achieved by a comprehensive team effort in breast cancer management. It seems that mammographic screening and medical adjuvant treatment both contributed to the decrease and that these two modalities may act in a synergistic way. Breast cancer specific survival increased significantly in the mid-1970s coinciding with the introduction of mammographic screening and medical adjuvant treatment. Survival is an important variable to predict outcome in the individual case provided the data used are relevant to the prevailing diagnostic and therapeutic conditions. A substantial proportion of operable cases experienced not only clinical but true cure. The number of cured cases increased after 1976. We even identified cases experiencing cure after treatment for distant metastatic disease. In a multivariate model including axillary nodal status and tumour size we found that the Linell-Ljungberg histological classification provides significant prognostic information.
Evaluation Of Demographic And Clinicopathological Characteristics Of Osteosarcoma Patients

INTRODUCTION: It is aimed that a retrospective analysis of 122 patients who were diagnosed with osteosarcoma and underwent surgical treatment between January 2002 and January 2015 at the Orthopedics and Traumatology Clinic of our Hospital. METHODS: Total of 122 patients (81 males, 41 females) were included in the study. All data were retrospectively and completely evaluated, 95,9% of the patients were operated, 72,7% of these patients, had limb salvage surgery and 27,3% had amputation. RESULTS: The mean age was 23.9 years (range 7-82 years), 50% of the patients were between 11 and 20 years of age and 66.3% of them were located in the knee (50.8% distal femur and 15.5% proximal tibia). At the time of diagnosis, 59% of cases were found to be Enneking Stage 2B. The most common tumor type was conventional osteosarcoma. DISCUSSION: When we examined the cases of osteosarcoma which diagnosed in our hospital, the distribution and features of tumor was similar to other cases that is in other hospitals in our country and the world literature.
Chinese medicine : modern practice

Risks of Traditional Chinese Herbal Medicine (E Ernst) Advances in Research of Angiogenesis Effect of Traditional Chinese Medicine (Z S Ding) Clinical Study on Treatment of Non-small Cell Lung Cancer by Chinese Herbal Medicine Combined with Bronchial Arterial Chemotherapy (C-L Liu) The Rationale of Combination Drug Formulas in Traditional Chinese Medicine (J Wang) Approaches of Chinese Medicine in Treating AIDS (W B Lu) Anti-liver Fibrosis with Integrated Traditional Chinese and Western Medicine (P Liu et al.) The Advances in the Treatment of Lung Cancer by Traditional Chinese Medicine (J-X Liu) Direction of TCM Modernization and Quality Control Mode (P-S Xie) A Critical Look at Traditional Chinese Medicine: A Paper in Support of WHO's Exploration on the Criteria of Evidence for Traditional Medicine (P-C Leung) Study of XS0601 on Preventing Restenosis after Coronary Interventional Treatment (K-J Chen) Research on Treatment of AIDS by Chinese Medicine (C-F Guan) Research and Production of Dachengqi Granules (X-Z Wu) Study on Evacuation of Hematoma and Traditional Chinese Medical Therapy in Hypertensive Mild and Severe Cerebral Hemorrhage (M-C Liu) Treatment of Alzheimer's Disease Based Upon Syndrome Differentiation of TCM and the Research of "Heart-Regulating Formula" (S-M Lin) The Conceptual Structure of the Chinese Quality of Life (CHQOL) Instrument (K Chan & L Zhao) Clinical and Experimental Studies on Acupuncture-drug Balanced Anesthesia and Analgesia in China (G-C Wu) Approaches in Developing an Integrative and Evidence-Based Curriculum in Chinese Herbal Medicine (K O'Brien et al.).
Multimodal pain management strategies in penile implant recipients

Penile prosthesis insertion can cause significant pain and discomfort. Traditional methods of pain control using narcotics alone have been shown to contribute to drug abuse and/or potential lethal overdose. Multimodal therapies are often used to reduce both pain and narcotic usage following surgery but until recently have been poorly characterized in prosthetic urology. Common medications used as part of an enhanced recovery after surgery are discussed. A prior novel investigation on multimodal therapy that spans the entire peri-operative and post-operative recovery period following penile implantation is also reviewed. Additionally, techniques for performing penile blocks are described with video demonstration of pudendal and penile nerve blocks.
OTT_A_215131 7361..7373

Xiaolin Pu* Changqing Dong* Wenyu Zhu Wei Li Hua Jiang 1Department of Oncology, Changzhou Second People’s Hospital, Changzhou, Jiangsu Province, People’s Republic of China; 2Department of Thoracic Surgery, Nanjing Chest Hospital, Nanjing City, Jiangsu Province, People’s Republic of China; 3Department of Oncology, Jiangsu Province People’s Hospital, Nanjing, Jiangsu Province, People’s Republic of China
Effect of diabetes mellitus on postoperative outcomes in patients undergoing emergency general surgery procedures.

Background: Diabetes Mellitus (DM) is a global health hazard affecting millions of people globally. A nationwide study conducted in Saudi Arabia showed the incidence and prevalence of DM were gradually increasing. Studies on the outcomes of emergency general surgery operations of diabetic patients are limited. The objective of this study is to compare the outcomes of diabetic patients undergoing emergency general surgery operations compared to those who are non-diabetic. Methods: Data for this cross-sectional study were collected using an observational clinical case series database, retrospectively, for patients undergoing emergency general surgery operations between July 2017 and December 2018 at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Patients were classified into diabetic and non-diabetic groups based on previous diagnosis at the time of presentation for their emergency procedure. Statistical analysis was utilized to investigate the association of diabetes with factors related to morbidity and mortality. Results: The total number of the participants was 325, wherein 177 (54.5%) were males. 185 (57%) were diabetic. We found significant association between diabetes mellitus and ICU admission and hospital readmissions compared to non-diabetic patients (odds ratio 1.772, relative risk 1.257 vs. 0.709, p=0.025). However, no statistically significant association was found between the diagnosis of diabetes and inhospital or 30-day mortality after emergency general surgery procedures. Conclusion: There are significant associations of the diagnosis of diabetes and worse postoperative outcomes in patients undergoing emergency general surgery procedures. Health care providers should give special attention as well as prompt and watchful perioperative care for this patients' population.