Miracle-dz/UniFAR-FTUs huggingface dataset:
Familial adenomatous polyposis: heterogeneity?

the current published literature, the only Caucasian persons shown to harbor the 9438 mutation are the five LHON probands previously reported Johns and Neufeld 1993) with >800 published Caucasian samples not harboring this mutation (table 1). The demonstration of this mutation in other populations is intriguing, and further analysis is needed to determine the importance of this in relationship to the pathogenetic significance of the 9438 mutation in LHON. There clearly are a number of unknown pathogenetic steps between the mtDNA genotype and the clinical occurrence of visual loss in LHON, and our understanding of the pathogenetic role of LHON-associated mtDNA mutations is at a very early stage.
The Performance of French LBO Firms: New data and new results

This paper investigates the operating performance of French targets of Leveraged Buy-Out (LBO) transactions during the 1995-2005 period. To benchmark LBO performance, I use a propensity score methodology to find a suitable non-LBO matching pair. The study finds that after the deal, the representative LBO firm exhibits higher operating returns of 4% to 5% relative to its matching control. This finding seems mostly due to increased gross margins, productivity gains, and working capital efficiency gains. These findings are not particular to a certain type of targets and are unchanged if I use the industry of the LBO firm as a benchmark.
Isospectral and Isoscattering Manifolds: A Survey of Techniques and Examples

The method of torus actions developed by the flrst and third au- thors yields examples of isospectral, non-isometric metrics on compact mani- folds and isophasal, non-isometric metrics on non-compact manifolds. In con- trast to most examples constructed by the Sunada method, the resulting ex- amples have difierent local geometry. In this review, we discuss insights into the inverse spectral problem gained through both of these approaches. One of Robert Brooks' ongoing research interests|and an area in which he made fundamental contributions|was the inverse spectral problem on Riemann- ian manifolds. Through ingenious constructions, he helped produce examples of Riemannian manifolds which were su-ciently symmetric to have the same spectral and scattering data, and yet were not isometric. Such examples illuminate the inverse spectral problem flrst of all by proving non-uniqueness, and secondly by helping to isolate geometric properties of Riemannian manifolds which are not de- termined by spectral data. In the present paper, we will review recent constructions of compact manifolds which are isospectral, and complete non-compact manifolds which are 'isoscattering' in a sense that we will make precise. We will emphasize recent progress in understanding 'isoscattering' manifolds and recent applications of the method of torus actions, due to the flrst and third authors, to 'isoscattering' problems.
Wave-particle Interactions In Rotating Mirrors

Wave-particle interactions in E×B rotating plasmas feature an unusual effect: particles are diffused by waves in both potential energy and kinetic energy. This wave-particle interaction generalizes the alpha channeling effect, in which radio frequency waves are used to remove alpha particles collisionlessly at low energy. In rotating plasmas, the alpha particles may be removed at low energy through the loss cone, and the energy lost may be transferred to the radial electric field. This eliminates the need for electrodes in the mirror throat, which have presented serious technical issues in past rotating plasma devices. A particularly simple way to achieve this effect is to use a high azimuthal mode number perturbation on the magnetic field. Rotation can also be sustained by waves in plasmas without a kinetic energy source. This type of wave has been considered for plasma centrifuges used for isotope separation. Energy may also be transferred from the electric field to particles or waves, which may be useful for ion heating and energy generation.
Digital Pre-Distortion of Carrier Frequency Offset for Reliable Wi-Fi Enabled IoTs

The Internet of Things (IoTs) will change the requirements for wireless connectivity significantly, mainly with regard to service coverage, data rate, and energy efficiency. Therefore, to improve robustness and reliability, WiFi-enabled IoT devices have been developed to use narrowband communication. However, narrowband transmission in WiFi such as IEEE 802.11ah causes relatively higher frequency error due to the reduced subcarrier space, which is larger than legacy wireless local area networks (WLANs) in 2.4/5 GHz frequencies. In a direct conversion receiver, this error degrades the signal quality due to the presence of direct current (DC) offset cancellation circuits. In this paper, a digital carrier frequency offset (CFO) predistortion scheme is proposed for a reliable communication link in dense networks. Evaluation results demonstrate that the proposed scheme can improve received signal quality in terms of packet error rate and error vector magnitude.
Remuneration Committee, Ownership Structure and Pay-for-Performance: Evidence from Malaysia

We examine the association between remuneration committee and ownership structures on pay-for-performance. We find that appropriately structured remuneration committee and institutional shareholders enhance the pay-for-performance elasticity which lends credence to their monitoring role. We also find that pay-for-performance relationship is weaker at high level of managerial ownership, consistent with agency theory prediction. However, we also show that among pay-without-performance firms, executives earn higher pay as managerial ownership increases, which suggests that rent extraction through overcompensation is likely, in tandem with managerial power theory. The evidence shows that both the principal-agent and managerial power views are relevant in explaining executive pay in Malaysia.
Production and inventory control with the base stock system

Recently much attention has been given to integral control of production and inventories in a multi product multi phase situation . Especially MRP and controlling safety stocks and safety time with MRP have been discussed . We propose a much simpler mode of control for a number of situations, namely base stock control (BSC) . BSC is known already but does not receive much attention . Within BSC a better and more natural treatment of safety stocks is possible . We used BSC in one application ; this resulted in good control with a low level of safety stocks and much less control effort than with
Building collagen IV smart scaffolds on the outside of cells

Collagen IV scaffolds assemble through an intricate pathway that begins intracellularly and is completed extracellularly. Multiple intracellular enzymes act in concert to assemble collagen IV protomers, the building blocks of collagen IV scaffolds. After being secreted from cells, protomers are activated to initiate oligomerization, forming insoluble networks that are structurally reinforced with covalent crosslinks. Within these networks, embedded binding sites along the length of the protomer lead to the “decoration” of collagen IV triple helix with numerous functional molecules. We refer to these networks as “smart” scaffolds, which as a component of the basement membrane enable the development and function of multicellular tissues in all animal phyla. In this review, we present key molecular mechanisms that drive the assembly of collagen IV smart scaffolds.
Culture Contact and Cultural Boundaries in Iron Age Southern Korea

abstract:Prevailing models of social development for the southern Korean Iron Age (ca. 300 b.c.–a.d. 300) focus on contact with China as well as the dynamic interaction between local polities to explain the development of socio-political complexity but the nature of this contact has not been critically examined or its more granular processes explored. This article uses two prominent grave good types discovered in southeastern Korean burials to question these models as well as conceptions of archaeological cultures in the region more generally. These objects, Chinese bronze mirrors and iron objects decorated with bracken-like spiral designs, both indicate significant interaction with Han China via its administrative commanderies, but their production and diverse mortuary contexts do not conform to any current model of culture contact, acculturation, hybridity, or entanglement. The variable production processes, expression of exotic motifs through these objects, and the way these objects were interred in graves suggests that we should look for cultural unity and early indicators of socio-cultural complexity within regions where local groups were particularly active in expressing their differences within a set of agreed-upon parameters. I argue that the southern peninsula is best described as a set of interdependent local groups with a similar ritual vocabulary, but little to no political unity even directly prior to the appearance of the Three Kingdoms polities of Paekche, Silla, and Kaya.
Hemodynamic alterations in the paravertebral venous plexus after spinal injury.

PURPOSE To assess the prevalence of altered venous hemodynamics after spinal cord injury. MATERIALS AND METHODS The authors performed venography in 200 ambulant patients and 107 patients with spinal injury. The hemodynamic characteristics of the paravertebral venous plexus were documented after pedal injection of contrast material. The hemodynamic and clinical data were correlated in patients with spinal cord injury. RESULTS Abnormal venous return via the paravertebral venous plexus in the absence of iliac or inferior vena caval occlusion was shown in 73 (68%) of the 107 patients with spinal injury. This paravertebral venous flow route is not related to the time between injury and examination. It was demonstrable in the early as well as late post-traumatic period and was reproducible at subsequent examinations. The paravertebral venous flow route was more commonly seen in cervical than thoracolumbar injuries and was closely related to the severity of neurologic deficit (P = .0012). CONCLUSION Abnormal vertebral venous hemodynamics occur in most patients with spinal cord injury and are more likely to occur in patients with complete neurologic deficit and cervical injury.
String-based haptic interface device for multi-fingers

We propose a novel two-handed multi-finger haptic interface device. This system is another kind of string based hand haptic display system. DC motors, rotary encoders, pulleys, and strings are used to measure the position of eight fingertips of the user in real time. When any fingertip comes into contact with any virtual object, the system will control the tension of the strings pulled by the motors to display force feedback at that fingertip of the user. We briefly describe the system as well as the methods used for calculation of the fingertip positions and the generation of force feedback.
Self-Surveillance by Adolescents and Young Adults Transitioning to Self-Management of a Chronic Genetic Disorder

Adolescents and young adults with Marfan syndrome (MFS) use information from self-surveillance to manage their disorder. Thirty-seven male and female adolescents with MFS aged 14 to 21 years were interviewed. They identified 58 distinct self-surveillance behaviors that fell into four categories and multiple subcategories (SCs): tracking phenotype (SCs: physical appearance, physical fitness, medical problems, and other observations); tracking medical care (SCs: medical evaluations and treatments, and pharmacotherapy); tracking behavior (SCs: personal choices and social relations); and tracking emotions (SCs: positive emotional impact and negative emotional impact). The frequency and range of self-monitoring increased with the age of the child. On average, a child of 14 self-monitored from 1 to 3 times per day, whereas a person aged 21 might self-monitor many more times per day. The patient—parent—physician relationship is the context for teaching adolescents and young adults self-surveillance skills. Self-surveillance by patients is first-line symptom assessment and an adjunct to medical monitoring.
Scalable Multibeam Antenna Arrays Fed by Dual-Band Modified Butler Matrices

A concept of dual-band multibeam antenna arrays that allows for efficient utilization of a common aperture has been proposed. The presented antenna arrays allow for achieving N-independent beams pointing at N different directions at higher frequency and N-independent beams at lower frequency pointing at N/2 different directions and having two orthogonal polarizations. As feeding networks, novel modified Butler matrices (BMs) have been proposed in which directional couplers having different properties in two frequency ranges have been for the first time utilized. To confirm the theoretical analysis, a dual-band multibeam antenna array fed by a modified 4 × 4 BM has been developed operating in 2.4 and 5.2 GHz frequency ranges.
Marka Değerinin Marka Genişlemesine Etkisi

Marka degeri yogun rekabet ortaminda sirketlerin sahip oldugu en onemli varlik halini almistir Marka genisleme stratejisi ile marka degerinin ana markadan yeni urunlere aktarilmasi soz konusu olmaktadir Bu strateji sayesinde firmalar yeni marka olusturmanin getirdigi maliyet ve zamandan tasarruf etmektedirler Marka degerinin yeni urunlere genisletilmesi; marka bilinirligi marka sadakati marka cagrisimlari ve algilanan kalitenin ana markadan yeni urune aktarimi ile gerceklesmektedir Bu arastirmada da marka degerini olusturan bu dort boyutun marka genislemesine etkisi incelenmistir Anahtar Kelimeler: Marka genisleme marka degeri marka degeri algilamalari
CMOS Process-Compatible High-Power Low-Leakage AlGaN/GaN MISHEMT on Silicon

We report on a novel Au-free CMOS process-compatible process for AlGaN/GaN metal-insulator-semiconductor high-electron-mobility transistors. The process starts from a 150-mm GaN-on-Si substrate with an embedded Si<sub>3</sub>N<sub>4</sub>/Al<sub>2</sub>O<sub>3</sub> bilayer gate dielectric, encapsulated by a high-temperature low-pressure chemical vapor deposited nitride layer. Power devices with a 20-mm gate width reach a maximum output current of 8 A, a breakdown voltage of 750 V, and a specific on-resistance <i>R</i><sub>on, sp</sub> of 2.9 mΩ·cm<sup>2</sup>. The off-state drain leakage at 600 V is 7 μA. We show robust gate dielectrics with a large gate bias swing.
On the role of viruses in human cancer.

Read more and get great! That's what the book enPDFd the role of viruses in human cancer will give for every reader to read this book. This is an on-line book provided in this website. Even this book becomes a choice of someone to read, many in the world also loves it so much. As what we talk, when you read more every page of this the role of viruses in human cancer, what you will obtain is something great.
Infratentorial posterior circulation stroke in a Nigerian population: Clinical characteristics, risk factors, and predictors of outcome

Background: Posterior circulation stroke (PCS), though less common, differs from stroke in anterior circulation in many aspects. Relatively, it portends a poorer prognosis. However, there is a paucity of data from African countries, in particular, where stroke is a menace. Objective: The study aimed to evaluate the etiology, clinical characteristics, outcome, and predictors of outcome in a cohort of patients with IPCS in Northwestern Nigeria. Materials and Methods: Out of 595 patients with stroke, we prospectively analyzed 57 patients with PCS in a Tertiary Care Center in Kano, Northwestern Nigeria. Patients were analyzed for demographic data, risk factors, clinical characteristics, stroke subtypes, mortality, and predictors of mortality. Results: Posterior circulation ischemic stroke accounted for 57 (9.6%) of 595 of all strokes seen in the study period. They comprised 44 males (mean age 47.8 ± 17.7) and 13 females (mean age 46.3 ± 13.7). Overall, their age ranged between 24 and 90 (mean age 47.4 ± 16.7). However, 52.7% of the patients were < 45 years of age. The most common site affected was the cerebellum seen in 33 (57.9%) patients. Hypertension was the most common risk factor (86%). Headache and vertigo were the most common features accounting for 83.6% and 86.3%, respectively. Thirty-eight (66.7%) patients had an ischemic stroke. Twenty-one (36.8%) of the patients died during the 1-month period of follow-up. Independent predictors of death in the study were hyperglycemia on admission and hemorrhagic stroke. Conclusions: IPCS occurred in a relatively younger age group. Headache and vertigo were the most common symptoms. The independent predictors of death in the study were hyperglycemia at presentation and hemorrhagic stroke.
Classical irregular scattering and its quantum-mechanical implications.

We analyze the effect of irregular classical scattering on the corresponding quantum-mechanical scattering matrix. Using semiclassical arguments, we show that the fluctuations in the S matrix and the cross sections are consistent with a random-matrix description (Ericson fluctuations). The results are illustrated by a numerical solution of a simple quantum problem, whose classical counterpart displays irregular scattering.
Management Accountants' Role in Dependent and Independent Companies: Does Ownership Matter?

The issue of (changing) accountants' roles has been given considerable coverage in recent years, in both professional and academic accounting literature. This paper contributes to the debate by comparing the roles of accountants in independent organisations with the roles of accountants in dependent, subsidiary organisations. Do accountants working in dependent organisations have larger or smaller roles, or different roles, to accountants working for independent organisations? One thousand qualified members of the Chartered Institute of Management Accountants (CIMA), UK, were randomly selected for a postal questionnaire survey. This survey provides evidence which contributes towards an understanding of the influence and role of parent companies in management accounting practices and the role of management accountants in their subsidiary companies. This study relies on the data collected through a questionnaire survey. However, the extent of the role and influence of parent companies, and also the ways in which they impact on subsidiary companies need to be studied in greater depth i.e., case study method. The findings of this study will assist business consultants, system designers and managers to understand the differences between dependent and independent companies when considering implementation of any changes in their existing management accounting systems and practices. Most of the evidence to date on the relationship between parent and subsidiary companies is subject to fairly basic analysis, and presented in very general terms. Thus, this paper aims to contribute to towards this important debate through making a comparison of changing roles between independent and dependent organisations.
Logic with Equality: Partisan Corroboration and Shifted Pairing

Herbrand's theorem plays a fundamental role in automated theorem proving methods based on tableaux. The crucial step in procedures based on such methods can be described as the corroboration problem or the Herbrand skeleton problem, where, given a positive integer m, called multiplicity, and a quantifier free formula, one seeks a valid disjunction of m instantiations of that formula. In the presence of equality, which is the case in this paper, this problem was recently shown to be undecidable. The main contributions of this paper are two theorems. The first, the Partisan Corroboration Theorem, relates corroboration problems with different multiplicities. The second, the Shifted Pairing Theorem, is a finite tree automata formalization of a technique for proving undecidability results through direct encodings of valid Turing machine computations. These theorems are used in the paper to explain and sharpen several recent undecidability results related to the corroboration problem, the simultaneous rigid E-unification problem and the prenex fragment of intuitionistic logic with equality.
In Sickness and In Health: Learning and Assessment Inside and Outside the New Zealand Qualifications Framework.

National qualifications frameworks are often considered to be a panacea for educators and educational institutions. In this paper I examine the implementation of the New Zealand Qualifications Framework, with particular emphasis on the relationship between educational institutions and industry partner organizations. It is argued that Government policy must take cognisance of differing skills of industry and education, and not create an imbalance in power than inhibits effective implementation of national frameworks. The issue is illustrated by a description of the experience of the implementation of the Diploma in Applied Technology at UNITEC Institute of Technology. (Asia-Pacific Journal of Cooperative Education, 2001, 2(1), 23-30).
Diffuse histiocytic lymphoma complicating chronic lymphocytic leukemia

Nine patients with chronic lymphocytic leukemia (CLL) who also developed diffuse histiocytic lymphoma (DH) are described. The incidence of patients with CLL developing DH was at least 3.3%. CLL existed for a median of 2 years before the diagnosis of DH. DH presented in 8 patients with abdominal symptoms and/or enlarging lymph nodes, spleen and liver. There were no consistent laboratory abnormalities associated with the onset of DH. In 4 of the patients the DH appeared to be localized. Eight of the 9 patients have died with a median survival of 2 months from the diagnosis of DH. Whether DH occurs as a result of „blastic transformation”︁ of pre‐existing CLL or is a second, unrelated malignancy is not certain. It is hypothesized that utilizing current therapies for DH might favorably influence survival.