Miracle-dz/UniFAR-FTUs huggingface dataset:
Loss of natural killer activity as an indicator of relapse in acute leukaemia

A role for naturally occurring cytotoxic cells in immunosurveillance against malignancy has been presumed in several studies. The natural killer activity (NKA) of peripheral blood mononuclear cells was therefore measured at regular intervals in patients with acute leukaemia and expressed specific cytotoxicity. Sixty controls had a median NKA of 33·6% (range 15·4–71). Seventy‐three patients with acute lymphoblastic leukaemia (ALL) and acute non‐lymphoblastic leukaemia (ANLL) with untreated or relapsed disease had a median activity of 2·4% (range 0–13·4) (P< 0·001), while 57 patients who had achieved complete remission had a median activity of 22·7% (range 9·5–64·4). In 15 patients, reductions of NKA were seen prior to 16 episodes of relapse. In ten of these (nine with ANLL and one with ALL), 11 relapses were preceded within 10 weeks by drops in NKA to less than 30% of remission levels. The median NKA of the group prior to the drop in activity was 25·5% and the median first low value was 60%. Five patients who relapsed after allogeneic bone marrow transplantation had significant, sustained drops in NKA, 5–9 weeks earlier. The median NKA prior to the drop was 25·6% and the median first low value was 8·0%. We therefore conclude that there was a marked reduction in NKA in patients with active acute leukaemia when compared with healthy blood donors and that this activity substantially improved in complete remission. All patients who relapsed had significantly reduced NKA which in some, significantly preceded the time of relapse. These data suggest that the regular assessment of NKA in patients with acute leukaemia may be a useful diagnostic tool.
Burnout in Medical Students: Examining the Prevalence and Associated Factors

Objective: Burnout has been described as a syndrome of emotional exhaustion, depersonalization, and decreased personal accomplishment, and may originate during medical school. The objective of this study is to determine the prevalence of burnout and contributing factors in medical students. Methods: A survey was administered to 249 medical students using a modified Maslach Burnout Inventory Human Services Survey (MBI-HSS) and scales of stressors, assessment of workload, relaxation, control, accomplishment, support systems, and demographics. Results: Moderate or high degree of burnout was seen in 21% of the first year class, 41% of the second year class, 43% of the third year class, and 31% of the fourth year class (P < 0.05). Lower support, higher stress, and lack of control over one's life were significantly related to burnout using multivariate analysis. Conclusions: Burnout progressively develops over the course of medical education, while a high level of support and low stress decreased burnout.
The positive relationship between codon usage bias and translation initiation AUG context in Saccharomyces cerevisiae

The relationship between the codon usage bias and the sequence context surrounding the AUG translation initiation codon was examined in 211 Saccharomyces cerevisiae mRNA sequences. The codon usage bias and the number of matches to optimal AUG context, (A/U)A(A/C)AA(A/C)AUGUC(U/C), for translation initiation showed a positive relationship, indicating that these two factors are evolutionally under the similar natural selection constraint at the translation level. A new index (AUGCAI=AUG Context Adaptation Index) for the measure of optimal AUG context was devised, and the importance of each position of AUG context was also examined. Copyright © 1999 John Wiley & Sons, Ltd.
Skeletal development in sloths and the evolution of mammalian vertebral patterning

Mammals show a very low level of variation in vertebral count, particularly in the neck. Phenotypes exhibited at various stages during the development of the axial skeleton may play a key role in testing mechanisms recently proposed to explain this conservatism. Here, we provide osteogenetic data that identify developmental criteria with which to recognize cervical vs. noncervical vertebrae in mammals. Except for sloths, all mammals show the late ossification of the caudal-most centra in the neck after other centra and neural arches. In sloths with 8–10 ribless neck vertebrae, the caudal-most neck centra ossify early, matching the pattern observed in cranial thoracic vertebrae of other mammals. Accordingly, we interpret the ribless neck vertebrae of three-toed sloths caudal to V7 as thoracic based on our developmental criterion. Applied to the unusual vertebral phenotype of long-necked sloths, these data support the interpretation that elements of the axial skeleton with origins from distinct mesodermal tissues have repatterned over the course of evolution.
A Roofline Performance Analysis of an Algebraic Multigrid PDE Solver

We present a performance analysis of a novel element-based algebraic multigrid (AMGe) method combined with a robust coarse-grid solution technique based on HSS lowrank sparse factorization. Our test datasets come from the SPE Comparative Solution Project for oil reservoir simulations. The current performance study focuses on one multicore node and on bound analysis using the roofline technique. We found that keeping a small value of spectral tolerance is most critical to achieve the best AMG solver performance. Our roofline bound estimate is within 23% accuracy compared to the actual runtime on a Cray XC30 12-cores processor. I. THE SA-ρAMGE ALGORITHM The Smoothed Aggregation Spectral Element Agglomeration AMG method was originally introduced by Brezina and Vassilevski [1] and implemented by Kalchev [2], [3]. It is a two-level algorithm that forms the prolongation operator P by first computing the eigenvectors of the low-end eigenvalues of the local stiffness matrices associated with the agglomerates and then multiplying by a matrix polynomial smoother (see [1] for the details of this step). The coarse-grid matrix is computed as Ac = PAP , where A is the finite-element stiffness matrix. The AMG solution cycle proceeds by alternating between the two levels. Specifically, cycle k transforms the current iterate xk into xk+1 using the following steps: 1) Pre-smoothing: yk ← xk +M(b−Axk) 2) Restriction: rc ← P (b−Ayk) 3) Coarse solution: xc ← A−1 c rc 4) Interpolation: zk ← yk + Pxc 5) Post-smoothing: xk+1 ← zk +M(b−Azk) In the above, the matrix M corresponds to a polynomial smoother such that M−1 = (I − pν(DA))A, where pν(t) is a polynomial and D is a diagonal matrix that can be efficiently computed from A. The polynomial is of degree 3ν+1, where ν is a user-specified parameter, and has the form pν(t) = ( 1− t τ1 )( 1− t τ2 ) · · · ( 1− t τ3ν+1 )
A forensic method for detecting image forgery

An Extensive growth in software technologies available on Internet results in tampering of images. The main problem in the real world is to determine whether an image is real or forged. In this paper we propose a new method that makes use of the codebook which is generated from the set of image features to determine the geometric manipulations that are occurred in the received image. In the proposed method, an image hash based on bag of visual words attached as signature to the image before transmission. At the destination the forensic hash is compared to detect the geometric manipulations that are applied to the received image. The spatial distribution of image features is encoded to deal with highly textured and contrasted tampering patterns. The proposed method detects all types of tampering.
Application Considerations for SiC MOSFETs 1 Application Considerations for Silicon Carbide MOSFETs

The key to successfully applying the SiC MOSFET requires an understanding of the device’s unique operating characteristics. In this section, the characteristics of Cree’s 1200V 80mΩ SiC MOSFET (CMF20120D) will be discussed. Comparisons will be made with other similar silicon devices along with application implications. The intention of this comparison is to illustrate the differences in operating characteristics, not to pick the best device. The comparison silicon devices are as follows: • 900V, 0.12  Si super junction MOSFET (SJMOSFET) Infineon IPW90R120C3 [2] • 1.2 kV, 20 A trench/field stop (TFS) Si IGBT Fairchild FGA20N120FGD [3] • 1.2 kV, 20 A non-punch though (NPT) Si IGBT International Rectifier IRGP20B120U [4] • 1.2 kV, 0.30  Si MOSFET (Si MOS8) Microsemi APT34M120J [5]
DEMOGRAPHIC RESPONSES TO FOOD AND SPACE COMPETITION BY JUVENILE STEELHEAD TROUT

I conducted two experiments in artificial stream channels, manipulating den- sity of competitors, food abundance, and the possibility of emigration, to test whether density-dependence can operate through these factors in populations of a stream-dwelling salmonid fish, juvenile steelhead trout (Oncorhynchus mykiss). In the absence of emigration, increasing levels of per capita food competition increased mortality, decreased growth, and increased the variance in size distributions of surviving individuals. Smaller fish were more likely to occupy less profitable areas of the stream channel than larger individuals and did so with increasing frequency as food abundance decreased and stocking density increased. When I allowed fish to emigrate from the stream channels, food and stocking density again influenced mortality, growth, and size distributions of survivors. Emigration was more likely at increasing levels of per capita competition; emigrants were smaller and in poorer condition than nonemigrants. The ability to emigrate from a population appears to normalize final size distributions and increase mean fish size within the stream channels. Thus, although both food and space are important factors shaping the demography of stream salmonid populations, neither appears to limit salmonid abundance exclusively.
Microbial Pathogenicity Black-pigmented Bacteroides species, Capnocytophaga species, and Actinobacillus actinomycetemcomitans in Human Periodontal Disease: Virulence Factors in Colonization, Survival, and Tissue Destruction

There have been many advances in the past decade in our knowledge of the microflora associated with periodontal diseases, the potential of specific periodontal bacterial species to destroy periodontal tissues, and the host responses to bacterial infections of the periodontium. It is the purpose of this and an accompanying paper, to present important features of the host-parasite interaction in human periodontal disease. The present communication emphasizes characteristics of periodontopathic bacteria which may enable them initially to colonize the host, to survive in the periodontal pocket, and possibly to invade the gingival tissue despite potentially effective host defense systems, and to destroy the collagenous periodontal ligament, the alveolar bone, and other tissue components surrounding the tooth. It seems reasonable to assume that a bacterial species must possess factors applicable to most if not all of the above aspects of the infectious process of periodontal disease in order to produce periodontitis.
Real-time high-quality stereo vision system in FPGA

Stereo vision is a well-known technique for acquiring depth information. In this paper, we present an FPGA-based real-time high-quality stereo vision system. By using AD-Census cost initialization, cross-based aggregation and semi-global optimization, the system provides high-quality depth results for highdefinition images. This is the first complete real-time hardware system that supports both cost aggregation on cross-based regions and semi-global optimization on FPGA. The system can adjust image resolution, parallelism degree, and support region size to achieve maximum efficiency flexibly during the implementation. We test the accuracy of the system on the Middlebury benchmark and some real-world scenarios with different image resolutions. The results show the accuracy is among the best of FPGA-based stereo vision systems and competitive with current top-performing software implementations. We demonstrate the system using an Altera Stratix-IV FPGA board, processing 1024 × 768 pixel images at 30 frames per second.
Ground Bounce Noise Induced by Crosstalk Noise for Two Parallel Ground Planes With a Narrow Open-Stub Line and Adjacent Signal Traces in Multilayer Package Structure

This paper investigates how ground bounce noise (GBN) is generated by crosstalk noises for two parallel ground planes with a narrow open-stub line (NOSL) and adjacent signal traces in a multilayer package structure. A noise reduction scheme and design guidelines for preventing intense noises (GBN and coupled noise) are also proposed. A graphical method that is based on wave tracing is also developed to elucidate the generation of crosstalk noise by adjacent signal traces on an NOSL. The mechanism of generation of the GBN by crosstalk noise can be elucidated based on reflection theory, open-stub quarter-wavelength resonance, and parallel-plane resonance. The time-domain simulation results are analyzed using a 3-D full-wave simulator, Computer Simulation Technology. Using an additional shorting via at the connection between the NOSL and parallel ground planes, the proposed noise reduction scheme can significantly reduce the GBN and coupled noise. Moreover, guidelines for designing the test structure to minimize noise (GBN and coupled noise) are presented. Finally, the simulation and measurement results in the time domain are compared to validate the proposed analysis and noise reduction scheme.
Mucopolysaccharidosis type I Hurler-Scheie syndrome: A rare case report

Mucopolysaccharidosis I (MPS I) is a rare inherited disorder that belongs to a group of clinically progressive disorders and is caused by the deficiency of the lysosomal enzyme, α1-iduronidase. MPS I has been recently classified into a severe (Hurler syndrome) and an attenuated type (Hurler-Scheie and Scheie syndromes). The purpose of this article was to describe a rare case of MPS type I, attenuated type (Hurler-Scheie) affecting a 15-year-old Indian child.
A framework for mobile SNS advertising effectiveness: user perceptions and behaviour perspective

This study develops and empirically tests a framework for mobile social network service (SNS) advertising effectiveness. The study sets the advertising value, attitude towards advertising, and behavioural intentions as the key variables for the assessment of advertising effectiveness. Regarding antecedents of advertising effectiveness, the study identifies the salient attributes of mobile SNS advertising as social, mobile convenience, and active control; the main sub-values of mobile SNS advertising as informativeness, entertainment, and irritation.
Analysis of Stacked Rectangular Microstrip Antenna

A stacked microstrip antenna with C-type feed is designed in order to enhance the bandwidth. The effect of the various parameters, such as the rotation feed angle (thetas), the variations of relative permittivity of parasitic patch (epsivr2), the distance of the feed point from the center (r), and the separation between two stacked patches (h2), have been discussed. Some designs give a good return loss under -40 dB and wide VSWR bandwidth, such as case#2 with epsivr2=4.26, case#4 with r=6.2 mm, case#5 with h2=6.8 mm, case#1,and case#2 with h2=8.2 mm. The simulated data are obtained using the IE3D simulator with method of moments (MoM) commercial code. An infinite ground plane has been considered for simulations; however, and due to a software constraint, substrate dimensions are infinite.
Topolithography and its application to the manufacture of 3D diode-based memories

Topolithography is a process wherein all of the information necessary to define a circuit is applied to a substrate in a single step. A multilevel surface topology defines the circuit for subsequent self-assembly so no photolithographic steps are required to manufacture a circuit resulting in substantially reduced costs. A transistor-less memory circuit is designed where high density storage, address decoding and I/O are implemented using an array of diodes.
Gear nano antenna for plasmonie photovoltaic

In this paper a novel nanoparticle structure has been presented to be used in plasmonic photovoltaic to enhance its efficiency. The proposed structure is a silver gear structure that is expected to make good enhancement of light absorption inside the semiconductor forming the photovoltaics (PV) in the visible range of frequencies (200-800 THz). The nano antenna particle is embedded inside the photovoltaics and produces highly confined near-field around the nanoparticle and withing the semiconductor. The extinction cross-section of the proposed nanoparticle in vacuum has been calculated versus the wavelength. Also, the modes of fields are studied and finally the effect of embedding this gear nanoparticle in a silicon photovoltaic is investigated by comparing its absorption with the conventional disk nanoparticle. The proposed structure enhances the light absorption in the near infrared region, which improves the efficiency of the PV solar cells.
Schedulability Analysis for Certification-friendly Multicore Systems

This paper presents a new schedulability test for safety-critical software undergoing a transition from single-core to multicore systems a challenge faced by multiple industries today. Our migration model, consisting of a schedulability test and execution model, is distinguished by three aspects consistent with reducing transition cost. First, it assumes externally-driven scheduling parameters, such as periods and deadlines, remain fixed (and thus known), whereas exact computation times are not. Second, it adopts a globally synchronized conflict-free I/O model that leads to a decoupling between cores, simplifying the schedulability analysis. Third, it employs global priority assignment across all tasks on each core, irrespective of application, where budget constraints on each application ensure isolation. These properties enable us to obtain a utilization bound that places an allowable limit on total task execution times. Evaluation results demonstrate the advantages of our scheduling model over competing resource partitioning approaches, such as Periodic Server and TDMA.
Somatostatin-like Immunoreactivity in the Retinae of Adult and Embryonic Chickens

Abstract Somatostatin, a tetradecapeptide that inhibits growth hormone release, has a widespread distribution in the central and peripheral nervous systems and other cell types. In the present investigation, the chicken neural retina was studied for the presence of structures exhibiting somatostatin-like immunoreactivity by utilizing an indirect immunofluorescence technique. Controls for specificity of staining were performed on alternate sections. Several types of distinctly labeled neurons and their processes were evident in sections of adult and late embryonic retinae. Cresyl violet staining showed that these neurons, which were scattered peripherally and more numerous centrally, occupied several strata within the inner nuclear, inner plexiform, and ganglion cell layers. Labeled neurites of immunoreactive perikarya coursed within these layers as well, often approaching other immunoreactive cells and fibers. The morphology and position of the somatostatin-containing neurons indicated that these neurons were amacrine, horizontal, or ganglion associational cells. These findings indicate that somatostatin is first detectable in the retina during the late embryonic stages of the chicken.
Geographical Indication for Jasmine Rice: Applying a Logit Model to Predict Adoption Behavior of Thai Farm Households

Geographical indications (GIs) have gained increasing interest since their protection has been ensured multilaterally under the TRIPS Agreement of the World Trade Organization (WTO). Thung Kula Rong-Hai Thai Hom Mali Rice (TKR) is the first officially registered GI Jasmine rice in Thailand. This paper aims at identifying factors that predict the behavior of Thai Jasmine rice farm households in adopting GI certification. Primary data of 370 Thai Jasmine rice farm households were collected through a formal survey in two districts of the Thung Kula Rong-Hai (TKRH) area. The results of the logistic regression analysis indicate that social and human capital variables significantly influence the decision of Thai Jasmine rice farm households to adopt GI certification.
Automatic gender recognition for “in the wild” facial images using convolutional neural networks

Automatic recognition of human demographical attributes has implications in a variety of domains, such as surveillance systems, human computer interaction, marketing etc. In this paper, we present an automatic gender recognition method from facial images based on convolutional neural networks. In order to train the network, we merged together several face databases and also gathered and annotated a ∼70000 facial images from the internet. We trained, evaluated and compared several network architectures that achieved impressive results on other computer vision tasks. The best accuracy is obtained using Inception-v4 network: 98.2% on our dataset, and 84% on Adience dataset.
Improved seam carving for content-aware image retargeting

When resizing image, effective means should not only consider geometric constraints, but also handle according to the image content. It is the fact that the image content in the middle is not more attractive than at the edge necessarily, the image resizing means on the basis of content is turning into a new hotspot in the image processing domain. Image resizing is also known as image retargeting. Firstly, this means treats the areas that attract human eyes' attention as more important regions, but the areas that not catch the people's eyes as unimportant districts, then to the greatest extent maintaining the important regions but changing unimportant districts in order to fit target image size. Therefore, this technology is referred to as content-aware image resizing. Among all the means relating to content-aware image resizing, seam carving algorithm's status is beyond all doubt, its advancement and innovation is better than other ways. In this article, seam-carving means was used as a starting point, after analysing the typical seam-carving algorithm, this paper presents a improved algorithm based on seam-carving. In our experiment, it is obvious to see that our new improved way enhances the resizing effects, avoids the distortion and makes better results.
Simulation of Pulsed High Voltage DC Source And Blumlein Transmission Line

In the reported article, we have simulated the pulsed high voltage direct current (DC) source and Blumlein transmission line by Multisimulation13 (National Instruments, Inc). In the generation of high voltage pulses at the optimum repetition rate, we have observed and investigated the waveform behavior of voltage in the Blumlein transmission line.We present the simulation results of pulsed high voltage DC source with theoutput of 55.4 kV, operating at 131 Hz.Further, voltage waveform across the Blumlein transmission line and its various parameters such as peak to peak voltage, root mean square voltage, peak to peak current, root mean square current and rate of oscillation of Blumlein transmission line are computed. The simulation of pulsed DC source and Blumlein transmission line by Multisimulation assisted in the designing and characterization of thehands-on high voltage source and Blumlein transmission line based transversely electrical excited at atmospheric (TEA) nitrogen laser.