Miracle-dz/UniFAR-FTUs huggingface dataset:
Information Classification in Web Agents using Fuzzy Knowledge for Distance Evaluation

The exponential grown of the World Wide Web has been possible to find any kind of useful information. However, there are serious problems to retrieve, manage and use this stored information. Different kinds of systems, like Search engines, MetaSearch engines, Spiders, Sofbots, Intelligent Agents or Web Agents have been developed by different researchers or companies. Those systems trying to retrieve and to use the information avoiding the overload of information. This paper remarks over one kind of these systems, we analyse how the Intelligent Software Agents retrieve, filter and store the retrieve information from the Web. To improve the Software Agents efficiently it is necessary for the agents to represent and to classify the retrieved data. In this work a fuzzy system that helps to the Intelligent Software Agents to make the classification is presented. The fuzzy system is developed to evaluate the appropriateness the different retrieve information from the Web and to recommend to the user the most appropriate founded, the fuzzy system calculates the appropriateness of each existing data and show them to the user, using different distances that will be analyzed in the paper. Key-Words: Web Agents, Intelligent Software Agents, Fuzzy Systems, Fuzzy Distance, Filtering Information
Location and Position Determination Algorithm For Humanoid Soccer Robot

The algorithm of location and position determination was designed for humanoid soccer robot. The robots have to be able to control the ball effectively on the field of Indonesian Robot Soccer Competition which has a size of 900 cm x 600 cm. The algorithm of location and position determination uses parameters, such as the goalpost’s thickness, the compass value, and the robot’s head servo value. The goalpost’s thickness is detected using The Centre of Gravity method. The width of the goalpost detected is analyzed using the principles of camera geometry to determine the distance between the robot and the goalpost. The tangent value of head servo’s tilt angle is used to determine the distance between the robot and the ball. The distance between robot-goalpost and the distance between robot-ball are processed with the difference of head servo’s pan angle and compass value using trigonometric formulas to determine the coordinates of the robot and the ball in the Cartesian coordinates.
Antimicrobial effect of Sliver Nanoparticles Synthesized by Chemical Reduction on some Bacteria and Fungi

Background; Nanotechnology involves the tailoring of materials at atomic level to attain unique properties, which can be suitably manipulated for the. Most of the natural processes also take place in the nanometer scale regime. Aim; The purpose from this experiment was to describe antimicrobial effects of sliver nanoparticles on some bacteria and fungi. Method; The morphology and size of particles of nanoparticles were determined by scanning electron microscopy (SEM) and Visible absorption spectrophotometer. Results; The antimicrobial effect was studied using the well agar diffusion and broth dilution techniques. The MIC of sliver nanoparticles were 30 ppm for Candida albicans, Candida tropicalis and Candida Krusei. Compared to other strains (E. coli, Pseudomonas aureginosa, S. aureus) 100 ppm. The antimicrobial activity was observed against all tested microorganisms at different concentration of nano sliver. The Ag NPs causes growth delay for treated isolated with different concentration used in the experiment (increased concentration, increased growth inhibition). Conclusion; The study revealed that sliver nanoparticles can be further developed as an antimicrobial agent, hence high activity against microorganisms. Keyword; Antimicrobial effect, Sliver Nanoparticles, bacteria and fungi
4-1BBL has a Possible Role in Mediating Castration-Resistant Conversion of Prostate Cancer via Up-Regulation of Androgen Receptor

4-1BB ligand (4-1BBL) was a transmembrane glycoprotein belonging to the tumor necrosis factor family. It was expressed on activated T lymphocytes and function as a co-stimulatory molecule via cross-linking with 4-1BB (a.k.a, CD137). In addition to its role in immune regulation, 4-1BBL transmitted signals into the cells on which it was expressed (reverse signaling). 4-1BBL represented a promising target for enhancing antitumor immune responses. Recent studies indicated that 4-1BBL also expressed in non-immune cells and possessed different functions in various types of cells. Here, we reported that 4-1BBL didn't express in normal prostate tissues and benign prostatic hyperplasia tissues, but it expressed in prostate cancer (PCa) tissues at moderate level. Expression of 4-1BBL was up-regulated during the transition from PCa to castration resistant prostate cancer (CRPC). Increasing expression of 4-1BBL not only promoted expression of androgen receptor (AR), but also augmented proliferation and invasion ability of prostate cancer cells in androgen deprivation environment. These results were further verified by xenograft tumor experiments. Meanwhile, inhibiting AR signal pathway by chemical antagonist was able to significantly reduce 4-1BBL mediated proliferation and invasion of PCa cells. These novel findings indicated that 4-1BBL might mediate prostate cancer progression to castration-resistant prostate cancer via enhancing expression and function of AR.
The effects of absent fathers on adolescent criminal activity: an economic approach

Abstract Simple ordinary least squares estimates indicate that absent fathers boost probabilities of adolescent criminal behavior by 16–38%, but those numbers likely are biased by unobserved heterogeneity. This paper first presents an economic model explaining that unobserved heterogeneity. Then turning to empirics, fixed effects, which attempt to address that bias, suggest that absent fathers reduce certain types of adolescent crime, while lagged-dependent variable models suggest the opposite. Those conflicting conclusions are resolved by an approach that combines those two estimators using an orthogonal reparameterization approach, with model parameters calculated using a Bayesian algorithm. The main finding is that absent fathers do not appear to directly affect adolescent criminal activity. Rather, families with absent fathers possess traits that appear to correlate with increased adolescent criminal behaviors.
PKC e Promotes Cardiac Mitochondrial and Metabolic Adaptation to Chronic Hypobaric Hypoxia by GSK 3 b Inhibition

Mitochondrial and Metabolic Adaptation to Chronic Hypobaric Hypoxia by GSK3b Inhibition JOY McCARTHY,* AMANDA LOCHNER, LIONEL H. OPIE, MICHAEL N. SACK, AND M. FAADIEL ESSOP Hatter Institute for Cardiovascular Research, University of Cape Town Medical School, Cape Town, South Africa Department of Medical Physiology, Stellenbosch University’s Faculty of Health Sciences, Tygerberg, South Africa Translational Medicine Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Cardio-Metabolic Research Group (CMRG), Department of Physiological Sciences, Stellenbosch, South Africa
SRPX2 and RAB31 are effective prognostic biomarkers in pancreatic cancer

Introduction: SRPX2 and RAB31 play important roles in tumorigenesis and metastasis; however, their prognostic value in pancreatic cancer remains unclear. This study aimed to investigate the potential interactions and effects of SRPX2 and RAB31 on the diagnosis and prognosis of pancreatic cancer. Methods: The expression of SRPX2 and RAB31 in pancreatic tumor tissues and cells was evaluated through database mining of the Oncomine, Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, and validated the results through immunohistochemistry (IHC) and Western blot in our clinical database. Protein-protein interactions were explored by immunofluorescence and Co-immunoprecipitation (Co-IP). Two hundred tissue microarray specimens from patients (79 training and 121 validation), who underwent curative pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) were used. Additionally, the association between the SRPX2 and RAB31 and prognosis of PDAC patients after surgery was analyzed. Results: The expression of SRPX2 and RAB31 was highly increased in pancreatic cancer, and there was a significant positive correlation between these two proteins. Co-IP showed the direct interaction between SRPX2 and RAB31. Kaplan-Meier analysis showed that positive expression of SRPX2 and RAB31 was associated with reduced disease-free survival (DFS) and overall survival (OS) of PDAC patients in the training set and the validation sets. Furthermore, multivariate analysis indicated that the 8th edition TNM stage and combination of SRPX2 and RAB31 were independent prognostic factors that associated with OS and DFS in the training, and the validation sets, respectively. Conclusions: The combination of SRPX2 and RAB31 can be important markers for the prognosis of pancreatic cancer.
Host plant preference of sucking pest complex to different tomato genotypes

Background: Different strategies have to be involved for keeping the pests in check and stabilizing the productivity of cropping system. Screening of varieties is one of the key strategies for selecting the least susceptible variety against pest attack to get higher crop yields despite pest incidence. Materials and Methods: The present study was conducted to observe the population dynamics of sucking pests on various tomato genotypes at Quetta, Balochistan during 2015. Six tomato genotypes i.e., Rutgar, Eden Oblong, Rio Granade, Nagina, Pakit and Roma were used in the study. Among sucking pests, population of aphids, thrips, whiteflies, jassids and mites were recorded since the early growth of various tomato genotypes. Results: Nagina genotype was more susceptible to attack of all sucking pests recorded, whereas Rutgar and Eden Oblong genotypes were the least susceptible against various sucking pests. Conclusion: It is therefore suggested that Rutgar and Eden Oblong genotypes should be grown to obtain higher fruit yield of tomato with lower densities of sucking complex pests.
Optimal Design of Second Order McClellan Transformation for Eightfold Symmetric Contours 2-D FIR Filters-Part II : Experiments and Results

1 Facultatea de Electronică şi Telecomunicaţii, Departamentul Comunicaţii, Bd. V. Pârvan Nr. 2 Timişoara Romania e-mail campeanu@hermes.ee. utt.ro Rezumat – Transformarea McClellan este un procedeu util de proiectare a filtrelor FIR bidimensionale prin intermediul unei transpuneri 1-D la 2-D. Algoritmul de proiectare calculează coeficienţii transformării McClellan prin minimizarea erorii pătratice dintre contururiile ideale ale filtrului 2-D şi cele furnizate de transformare. Tipul caracteristicii filtrului 2-D şi simetria ei octală impun restricţii în proiectare care devine astfel o problemă de minimizare a celor mai mici pătrate cu constrângeri. Scopul principal al lucrării este să extindă metoda în cazul transformării McClellan de ordinul 2. Principalul obstacol în calea acestei extinderi constă în dificultatea de a asigura monotonia transformării în planul 2-D. Rezolvarea problemei se face printr-o procedură iterativă descrisă în lucrare. Partea I a acestei lucrări în două părţi se ocupă cu deducerea algoritmului iterativ de proiectare a transformării McClellan prin metoda celor mai mici pătrate cu constrângeri. Paartea a II-a prezintă diferite exemple de proiectare a filtrelor 2-D prin această metodă. Pentru filtrele 2-D cu contur circular şi romboidal, rezultatele obţinute sunt comparate cu cele furnizate de transformarea McClellan de ordinul I.
High WNT6 expression indicates unfavorable survival outcome for patients with colorectal liver metastasis after liver resection

Objective: As a member of the Wnt family, WNT6 contributes to tumorigenesis and the development of various types of cancer. However, the expression status of WNT6 in colorectal liver metastasis (CRLM) and its prognostic value remain to be elucidated. In this study, we evaluated the association of WNT6 expression with survival outcomes in CRLM patients undergoing liver resection. Methods: The medical records of 106 consecutive CRLM patients undergoing curative tumor resection between October 1996 and December 2011 were retrospectively selected. WNT6 expression was detected using immunohistochemistry (IHC) analyses on paraffin-embedded specimens. The IHC score was determined according to the percentage and intensity of positively stained cells. Recurrence-free survival (RFS) and overall survival (OS) were analyzed using the Kaplan-Meier method and the log-rank test, and independent prognostic factors were determined by Cox regression modeling. Results: We found that WNT6 was commonly expressed in 93.4% (99/106) of colorectal cancer tissues. The median IHC score of WNT6 expression was significantly lower in patients receiving preoperative chemotherapy than those without preoperative chemotherapy (1.33 vs. 2.33, P = 0.033). Survival analysis indicated that patients with high WNT6 expression had poorer 5-year OS than those with low WNT6 expression (31.0% vs. 62.2%, P = 0.012). The 5-year OS rate was significantly lower in the high WNT6 group than in the low WNT6 group (36.8% vs. 79.9%, P = 0.013) in low-risk patients but was comparable among the high-risk patients (22.7% vs. 34.7%, P = 0.433). Multivariate analysis indicated that high WNT6 expression was independently associated with poor OS (hazard ratio [HR]: 2.089; 95% confidence interval [CI]: 1.231-3.545; P = 0.006). Conclusions: High expression of WNT6 was associated with unfavorable oncologic prognosis in patients with CRLM undergoing liver resection. Detection of WNT6 expression may be valuable for guiding postoperative treatment.
Risk of Acute Kidney Injury following Percutaneous Coronary Interventions using Radial versus Femoral Vascular Access: Insights from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2)

background Trans radial percutaneous coronary intervention (TRI) does not involve catheter manipulation in the descending aorta, whereas transfemoral PCI (TFI) does. Therefore, the risk of acute kidney injury (AKI) post PCI might be influenced by vascular access site. We compared risks of AKI and nephropathy requiring dialysis (NRD) among patients treated with TRI and TFI. Methods and Results We included patients across 47 hospitals in Michigan. Primary endpoint was AKI (serum creatinine increase > 0.5 mg/dL). Secondary endpoints were NRD and post procedural bleeding. Odds ratios (OR) for study endpoints were calculated for the entire and a propensity-matched population, reported as crude and values adjusted for preprocedural calculated AKI risk. Between 2010 and 2012, 82,225 PCI procedures were performed of which 8915 were TRI. After adjustment, TRI was associated with a reduction in AKI (OR 0.76, 95% CI 0.62–0.92) and bleeding with a trend towards lower NRD risk. The propensity-matched population consisted of 8,857 procedures per group. In this population, TRI was associated with lower adjusted odds of AKI (OR 0.74, 95% CI 0.58-0.96), and bleeding (OR 0.47, 95% CI 0.36-0.63) but no difference in NRD was observed. Although post procedural bleeding was independently associated with AKI (OR 2.86, 95% CI 1.754.66) in the propensity-matched population, the lower odds of AKI was not mediated by a reduction in bleeding with TRI. Sensitivity analysis demonstrated that the observed association between access site and AKI could potentially be explained by a moderately strong unknown confounder. conclusion The risk of AKI was significantly lower after TRI compared with TFI. This finding needs to be evaluated in randomized controlled trials. Risk of nephropathy after radial vs femoral PCI 163 C ha p te r 1
The Effect of Bifidobacterium Breve and Lactobacillus Salivarius on the Isoepoxydon Dehydrogenase ( Idh ) Gene Expression Involved in Patulin Biosynthesis Produced by Penicillium Expansum

Penicillium expansum produced the toxin patulin in pome fruits. To evaluate the molecular mechanism by which the treatment of probiotic bacteria Bifidobacterium breve and Lactobacillus salivarius could modulate patulin production, isoepoxydon dehydrogenase (idh) gene involved in the biosynthesis of patulin were measured using real time-PCR technique. The result of this study found that the supplementation with B. breve and L. salivarius down-regulate the relative expression of isoepoxydon dehydrogenase (idh) gene . However, these finding suggested that these bacteria decreased patulin production through effect on the genes responsible for its biosynthesis which can be the main mechanism by which patulin reduced in the presence of the these bacteria. Key word: Patulin, lactic acid bacteria, Penicillium expansum, gene
Hox Temporal Collinearity: Misleading Fallacy or Essential Developmental Mechanism?

Kondo and collaborators recently reported the absence of Hox temporal collinearity in Xenopus tropicalis. They found none in the initiation of accumulation of Hox transcripts (detected via RNA seq). And none in the initial expression sequence of primary unprorocessed transcripts (Identified by using qRT-PCR against introns or intron-exon boundaries). Nor in the initial acquisition by Hox gene DNA of a mark for active chromatin. These findings are in conflict with the idea that temporal collinearity has to do with the initiation of Hox gene transcription or with the opening of and a progression from repressed to active states in Hox chromatin. But collinear acquisition of the same active chromatin mark has been shown by others in murine 5’ Hoxd cluster genes.The reason for this difference is unknown . This careful study thus indicated that the initiation phase of Hox expression shows no temporal collinearity in X. tropicalis. A previous study in X. laevis from the same group also showed that the sequence of times for reaching (normalised) half maximal Hox expression showed no temporal collinearity. These conclusions are likely to be correct. These authors do however also conclude that “experimental evidence for the temporal collinearity hypothesis is not strong” There is however strong evidence that Hox temporal collinearity does occur in early vertebrate embryos. Below. I present and discuss 3 lines of evidence to resolve the present conflict I argue that Hox temporal collinearity actually does exist and that it is part of a central mechanism in early development.
Collecting and generating new ideas

In the last decade, the amount of free, large, and open digital structured data available on the Internet, and the demand for search mechanisms to explore such data, has been continuously increasing thanks to the use of technologies and initiatives such as RDF, Linked Open Data, the evolution of databases, etc. Moreover, users have become used to searching for information through keyword-based search interfaces due to the success of web search engines such as Google or Bing. As a result of these parallel developments, a requirement to provide similar techniques to support keyword-based queries over structured data sources in multi-source scenarios, and in the absence of direct access to the instances, has appeared. The COST Action ”Semantic Keyword-Based Search on Structured Data Sources” (KEYSTONE) aims towards building successful and effective solutions to overcome current limitations with keyword-based search, by creating synergies among researchers, technologists and users from different disciplines that have traditionally only partially overlapped, such as Semantic Data Management, the Semantic Web, Information Retrieval, Artificial Intelligence, Machine Learning, User Interaction, and Natural Language Processing. Thus, the main goal of KEYSTONE is launching and establishing a cooperative network of researchers, practitioners and application domain specialists, and coordinating and fostering collaboration among them to enable research activities and technology transfer in the area of keyword-based search over structured data sources. In this context, as a first activity of the KEYSTONE Action, the Management Committee decided to organise a meeting in Leiden, Netherlands during March 2014. The goals of that meeting were mainly two-fold: 1) to present
Concept of VPN on Cloud Computing for Elasticity by Simple Load Balancing Technique

Cloud computing has been under the glare as an emerging IT trend in the federal government for several years. As defined by The National Institute of Standards and Technology, cloud computing is a model for enabling convenient, on-demand network access to a shared pool of configurable computing resources (e.g., networks, servers, storage, applications, and services) that can be rapidly provisioned and released with minimal management effort or service provider interaction. In this paper we introduced the concept of virtual private network based on Cloud Computing by using some simple techniques like load balancing , topology etc. This VPN service is fully dedicated to the Small-and-medium size companies which are based on pay as much as used policy, it is fully SaaS type service provider. The model which is proposed here is truly adjust the resources consumed on the fly after careful evaluation of the resource usage in the basis of exhaustible and elastic cloud resources.
How to write a good state of the art: should it be the first step of your thesis ?

In scientific writing, the state of the art describes the current knowledge about the studied matter through the analysis of similar or related published work. It might provide a comprehensive overview of what has been done in the field and what should be further investigated, in order to help formulating the problems and hypothesis the thesis intends to address. Producing a good state of the art might be considered the main initial step of a PhD thesis. This is however a challenging task that involves analysing, comparing, evaluating and linking different sources (i.e., many hours of reading and content organisation). This task may be also considered an intimidating task that requires the help and guiding of the thesis supervisors. While starting a thesis by producing (good) state of the art is a nice starting point, this process is non linear and involves many iterations. It requires as well to be continuously and incrementally refreshed. The different types of state of the art (to be incorporated into a paper, a survey article or thesis), the steps of writing a (good) state of the art and some tips facilitating the process will be discussed.