Miracle-dz/UniFAR-FTUs huggingface dataset:
Scale-up thermostable α-amylase production in lab-scale fermenter using rice husk as an elicitor by Bacillus licheniformis-AZ2 isolated from Qinarje Hot Spring (Ardebil Prov. of Iran)

Background and purpose: Amylases are commercially important enzymes with various biotechnological, clinical and medical applications. This study aimed at scaling up α-amylase production elicited by rice husk in stirred-fermenter using Bacillus lichneniformis-AZ2 isolated from Qinarje Hot Spring. Materials and methods: Effect of temperature, aeration rate and agitation speed on bacterial growth and ɑ-amylase production were investigated under batch fermentation process in a 3-Lit stirred-fermenter. OFAT method was followed to select optimum level of each parameter. Other factors were set upon the results of previous experiments carried out in shake-flask scale. Results: Maximum α-amylase production of 17.66 ± 0.87 U/mL (2.1 folds more than shake-flask cultures) was achieved in stirred-fermenter with optimized agitation speed of 100 rpm and 1 vvm aeration rate at 37oC after 60 h of incubation. This time was shorter than the corresponding fermentation time obtained from shake-flask experiments by half. A comparison of kinetic parameters of fermentation in stirred-fermenter and shake-flask cultures revealed that B. licheniformis-AZ2 was more active to synthesize ɑ-amylase in fermenter. In shaken cultures Qx, Qp, Yp/x, µmax, qp and td, were 0.27 (g/L/h), 228.6 (U/L/h), 13.64 (U/g), 0.055 (h-1), 0.76 (U/g/h) and 12.48 h, whereas in stirred-fermenter the above values were 0.40 (g/L/h), 723.1 (U/L/h), 45.17 (U/g), 0.120 (h-1), 5.42 (U/g/h) and 5.78 h, respectively. Conclusions: SmF in stirred-fermenter is a potential strategy for ɑ-amylase production. Although for commercialization further studies are needed in pilot-scale. Rice husk as a low-cost agro-waste is preferable to use as the carbon and energy sources, which provides a great ɑ-amylase elicitation.
Experimental Study Of Boilover In Crude Oil Fires

An experimental study of boilover phenomena in connection with crude oil and kerosene pool fires was carried out in the large scale test facilities of the Fire Research Institute of Japan. Arabian light crude oil was burned in steel pans ranging from a circular one with a diameter of 0.3 m to a square one with a 2.7 m side. An oil layer of 10 mm to 100 mm was floating on water in the pans. The intensity of boilover was found to increase with increasing fuel thickness. An almost tenfold increase in the amount of unburned residue was found to occur as the layer thickness was increased from 40 mm to 50 mm, Resul ts of measurements of liquid and gas temperatures, burning rates and radiative heat outputs are reported.
Large-strain piezoelectric actuators using controlled structural buckling

Buckling is a highly nonlinear and singular phenomenon in thin beams, and is usually an undesired characteristic that must be prevented from occurring in engineered systems. Buckling, however, can be a useful mechanism for gaining extremely large displacement amplification, since a infinitesimal displacement in the axial direction of the beam may lead to a large deflection in the middle of the beam. This thesis presents a novel large-strain piezoelectric actuator exploiting the buckling of a structure with imbedded piezoelectric stack actuators. The realization of this buckling actuator began by rethinking the paradigm of where PZT stacks are placed in traditional flexure-based displacement amplification mechanisms. Although the free displacement of a PZT stack is only 0.1% of the stack length, the buckling mechanism can produce a large bipolar displacement that is approximately 150 times larger than the original PZT displacement. Furthermore, the structural buckling produces a pronounced nonlinearity in output impedance; the effective stiffness viewed from the output port varies as a function of output displacement, which can be a useful property for those applications where actuator stiffness needs to vary. Buckling is controlled with phased activation of the input units and either 1) a strategically placed redirecting stiffness or 2) multiple buckling units working in parallel. Thesis Supervisor: H. Harry Asada Title: Ford Professor of Mechanical Engineering
Primary Extranodal Hodgkin's Lymphoma presenting with a Single Pelvic Mass

Introduction: Although lymphomas can arise from a wide variety of tissues, primary extranodal presentation is predominantly a feature of non-Hodgkin’s lymphomas. Primary pelvic extranodal Hodgkin’s lymphoma is a rare malignancy. We presented a case of primer retroperitoneal Hodgkin’s lymphoma initially presumed gynecologic malignancy. We discussed its rarity, staging and management. Case report: A 75-year-old woman was referred to our hospital with persisting pelvic mass. Pelvic examination revealed an ill-defined immobile mass with hard in consistency. The mass 100 × 75 mm in diameter, invading right parametrium, perivesical space and bladder wall was detected in CT and there were no signs of metastases or enlarged lymph nodes. Diagnostic laparoscopy was suggested but the patient refused the surgery due to her advanced age. One year later, she presented with the symptoms of fever, sweats and fatigue. Hodgkin’s lymphoma was diagnosed via laparoscopic biopsy of the mass located at retroperitoneal space anteriorly to the uterus. CT examination revealed multiple swollen lymph nodes and a pulmonary nodule; thus, stage 4 disease was established. International prognostic score was 2, indicating 67% progression free survival; however, patient died due to respiratory failure after the first course of ABVD chemotherapy. Conclusion: Although gynecologists rarely experience primary extranodal lymphomas particularly Hodgkin’s disease, lymphoid malignancies should be kept in mind in differential diagnosis of pelvic masses. This disease can rarely arise adjacent to gynecologic organs in retroperitoneal space, and this presentation can be misinterpreted as a gynecological malignancy.
In situ net primary productivity of an Antarctic fast ice bottom algal community

Net primary production was measured in situ in an Antarctic fast ice bottom algal mat at Cape Evans, McMurdo Sound, Antarctica. Under-ice PAR irradiances between 18 November and 4 December 1997 were between 3 and 55 μmol photons m-2 s-1. This produced a net oxygen export between 0.0084 and 0.0440 nmol O2 cm-2 s-1. Pmax was 0.034 nmol O2 cm-2 s-1, Ek was 14 μmol photons m-2 s-1 the compensation point was approximately 2 μmol photons m-2 s-1. These values are equivalent to a carbon-based production of 3.50 to 18.46 mg C m-2 h-1 and assimilation numbers of between 0.294 and 2.01 mg C mg-1 chl ah-1. Production levels on sunny days were so high that oxygen bubbles formed at the ice water interface and presumably contributed to the demise of the algal mat. Grazing by amphipods was also observed. While increasing net oxygen export was found to be strongly correlated with increasing irradiance, increasing under-ice current velocity was also found to increase production. The reduction in diffusive boundary layer thickness caused by increasing current velocity would have allowed both a more efficient transport of nutrients into the mat and a more efficient transport of oxygen away from the mat. Accumulation of sea ice algal biomass is not just a function of light but is also influenced by under-ice current velocity and possibly by oxygen build-up and grazing by amphipods and other invertebrates. In spite of the high under-ice irradiances reported from Cape Evans, loss mechanisms such as grazing and possibly oxygen toxicity were able to prevent the build-up of additional biomass.
Entanglement and area laws in weakly correlated gaussian states

Fil: Matera, Juan Mauricio. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - La Plata. Instituto de Fisica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Fisica La Plata; Argentina
Characterization the equivalenceof of robustification and regularization matrixin linear and regression

The are notion developing in of statistical methods machine which learning robust to adversarial perturbations in underlying data interest in the has of been the subject increasing recent years. A common feature is of this work that adversarial the robustification often corresponds regularization exactly to methods a plus a which appear as loss function penalty. In this deepen the paper we and extend understanding in of and achieved the connection between robustification regularization (as by penalization) regression problems. Specifically, (a) characterize In linear the context of regression, we precisely conditions under which on the model of uncertainty are used and on and the loss function penalties robustification regularization equivalent. (b) We extend the regression characterization of and robustification regularization matrix to problems (matrix and completion Principal Component Analysis). © 2017 Elsevier All B.V. rights reserved.
Chapter 1 INTRODUCTION TO THE KINETIC MONTE CARLO

Monte Carlo refers to a broad class of algorithms that solve problems through the use of random numbers. They first emerged in the late 1940’s and 1950’s as electronic computers came into use [1], and the name means just what it sounds like, whimsically referring to the random nature of the gambling at Monte Carlo, Monaco. The most famous of the Monte Carlo methods is the Metropolis algorithm [2], invented just over 50 years ago at Los Alamos National Laboratory. Metropolis Monte Carlo (which is not the subject of this chapter) offers an elegant and powerful way to generate a sampling of geometries appropriate for a desired physical ensemble, such as a thermal ensemble. This is accomplished through surprisingly simple rules, involving almost nothing more than moving one atom at a time by a small random displacement. The Metropolis algorithm and the numerous methods built on it are at the heart of many, if not most, of the simulations studies of equilibrium properties of physical systems. In the 1960’s researchers began to develop a different kind of Monte Carlo algorithm for evolving systems dynamically from state to state. The earliest application of this approach for an atomistic system may have been Beeler’s 1966 simulation of radiation damage annealing [3]. Over the next 20 years, there were developments and applications in this area (e.g., see [3–7]), as well as in surface adsorption, diffusion and growth (e.g., see [8–17]), in statistical physics (e.g., see [18–20]), and likely other areas, too. In the 1990’s the terminology for this approach settled in as kinetic Monte Carlo, though the early papers typically don’t use this term [21]. The popularity and range of applications of kinetic Monte Carlo (KMC) has continued to grow and KMC is now a common tool for studying materials subject to irradiation, the topic of this book. The purpose of this chapter is to provide an introduction to this KMC method, by taking the reader through the basic concepts underpinning KMC and how it is typically implemented, assuming no prior knowledge of these kinds of simulations. An appealing property of KMC is that it can, in principle, give the exact dynamical evolution of a system. Although this ideal is virtually
Diffusion of ideal gases in capillaries and porous solids

The steady state diffusion of gases through capillaries or through the pores of a solid when the total pressure in the system is constant is considered. It is shown that the ratio of the molar diffusion rate of the lighter gas to that of the heavier gas must be equal to the square root of the ratio of the molecular weight of the heavier to the lighter. From simple momentum transfer considerations a diffusion equation is derived to describe the diffusion rate as the nature of the process changes from ordinary mutual diffusion to Knudsen diffusion. This equation is shown to give good agreement with experimental measurements of diffusion rates in porous solids. A structural parameter of the porous solid, the diffusion ratio, is calculated from the experimental results and compared with the experimental value of the same ratio found from electrical resistance ratios and from flow measurements. (auth)
Screening of arbuscular endomycorrhizal fungi for establishment of micropropagated pineapple plants

plusieurs champignons endomycorhizogenes a arbuscules (Glomus clarum (LPA 16 ), Scutellispora pellucida (LPA20), Glomus sp (LPA21), Glomus sp (LPA22) and Glomus sp (LPA25)) ont ete testes pour leur developpement et leur effet sur la croissance de 3 varietes d'ananas micropropages (Queen Tahiti, Cayenne lisse (clone CY0) et Spanish) cultives dans un sol acide et dans une salle climatisee aux conditions tropicales. Pour les 3 varietes d'ananas testees, les vitroplants endomycorhizes presentent une meilleure croissance que les non inocules []
Effects of Bold Key Terms on Judgments of Learning and Reading Comprehension

ii Acknowledgements . iii List of Tables . vii List of Figures . ix Chapter 1: Introduction . 1 General Metacognitive Components . 4 Specific Metacognitive Components . 5 Cue-Utilization: Judgments of Learning . 14 Construction-Integration Model (CI) . 20 Rationale for Current Studies . 23 Pilot Study . 24 Method . 24 Participants . 24 Materials . 32 Procedure . 25 Results . 27 Global JOLs . 27 Term-specific JOLs . 27 Test Performance . 27
DISCOVERY OF AN INNER DISK COMPONENT AROUND HD 141569 A

We report the discovery of a scattering component around the HD 141569 A circumstellar debris system, interior to the previously known inner ring. The discovered inner disk component, obtained in broadband optical light with Hubble Space Telescope/Space Telescope Imaging Spectrograph coronagraphy, was imaged with an inner working angle of 0. ″25, and can be traced from 0. ″4 (∼46 AU) to 1. ″0 (∼116 AU) after deprojection using i = 55°. The inner disk component is seen to forward scatter in a manner similar to the previously known rings, has a pericenter offset of ∼6 AU, and break points where the slope of the surface brightness changes. It also has a spiral arm trailing in the same sense as other spiral arms and arcs seen at larger stellocentric distances. The inner disk spatially overlaps with the previously reported warm gas disk seen in thermal emission. We detect no point sources within 2″ (∼232 AU), in particular in the gap between the inner disk component and the inner ring. Our upper limit of 9 ± 3 MJ is augmented by a new dynamical limit on single planetary mass bodies in the gap between the inner disk component and the inner ring of 1 MJ, which is broadly consistent with previous estimates.
The spectrum of rotating black holes and its implications for Hawking radiation

The reduced phase space formalism for quantizing black holes has recently been extended to find the area and angular momentum spectra of four-dimensional Kerr black holes. We extend this further to rotating black holes in all spacetime dimensions and show that although as in four dimensions the spectrum is discrete, it is not equispaced in general. As a result, Hawking radiation spectra from these black holes are continuous, as opposed to the discrete spectrum predicted for four-dimensional black holes.
Major Histocompatibility Complex Class Ill Genes and Susceptibility to Immunoglobulin A Deficiency and Common Variable Immunodeficiency

We have proposed that significant subsets of individuals with IgA deficiency (IgA-D) and common variable immunodeficiency (CVID) may represent polar ends of a clinical spectrum reflecting a single underlying genetic defect. This proposal was supported by our finding that individuals with these immunodeficiencies have in common a high incidence of C4A gene deletions and C2 rare gene alleles. Here we present our analysis of the MHC haplotypes of 12 IgA-D and 19 CVID individuals from 21 families and of 79 of their immediate relatives. MHC haplotypes were defined by analyzing polymorphic markers for 11 genes or their products between the HLA-DQB1 and the HLA-A genes. Five of the families investigated contained more than one immunodeficient individual and all of these included both IgA-D and CVID members. Analysis of the data indicated that a small number of MHC haplotypes were shared by the majority of immunodeficient individuals. At least one of two of these haplotypes was present in 24 ofthe 31 (77%) immunodeficient individuals. No differences in the distribution of these haplotypes were observed between IgA-D and CVID individuals. Detailed analysis of these haplotypes suggests that a susceptibility gene or genes for both immunodeficiencies are located within the class III region of the MHC, possibly between the C4B and C2 genes. (J. Clin. Invest. 1992.89:1914-1922.)
The Application of Optical Coherence Tomography ( OCT ) in Neurological Disease

Optical coherence tomography (OCT) was first described by Huang et al. in 1991 and was first used to image the retina in 1993. OCT technology has evolved rapidly enabling the production of in vivo high resolution cross-sectional and three-dimentional images of the ocular microstructure in real time. These OCT images closely reflect histological sections of the macula and fovea, hence the term “optical biopsy. ” The technique was initially used for the diagnosis and management of ophthalmological diseases but over the last decade has been increasingly recognized for its applications in neurology.
TECHNIQUE APPLICATIONS PACKING OF INTERVERTEBRAL SPACES WITH OXIDIZED REGENERATED CELLULOSE TO PREVENT THE RECURRENCE OF LUMBAR DISC HERNIATION

Accepted, December 18, 2002. OBJECTIVE: To investigate the impact of packing of intervertebral spaces with oxidized regenerated cellulose (ORC) on the incidence of recurrence of lumbar disc herniation (LDH). METHODS: We retrospectively reviewed 158 consecutive patients who underwent surgery for a newly diagnosed LDH and had a minimum of 18 months of follow-up. Single-level (151 patients) and two-level (7 patients) procedures accounted for 165 microdiscectomies. After microsurgical removal of disc herniation and curettage, the interspaces were tightly packed with ORC. RESULTS: The average hospital stay was 1.47 days, without any relevant and permanent complications. In particular, complications related to intervertebral ORC packing were never observed. At a median follow-up of 29 months (range, 18–51 mo), the pain decreased or disappeared in almost all patients and the patient satisfaction rate was very high. A recurrence of LDH was observed in two patients (1.34%), both of whom needed a second operation. Three patients (2.01%) experienced a disc herniation involving another intervertebral space. CONCLUSION: Our preliminary results suggest that the packing of intervertebral spaces with ORC at the end of microdiscectomy is a safe technique that may reduce the incidence of recurrent LDHs, although the true impact of this technique on long-term follow-up is still unclear. At the moment, it seems reasonable to assume that this technique should be used only under the auspices of large clinical investigations with prospective and randomized protocols.
Aug-2017 Final Report : An FPGA Testbed for Characterizing and Mapping

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Production of stable bcs class ii drug suspensions by melt emulsification and subsequent incorporation into polymer strip films

PRODUCTION OF STABLE BCS CLASS II DRUG SUSPENSIONS BY MELT EMULSIFICATION AND SUBSEQUENT INCORPORATION INTO POLYMER STRIP FILMS by Emanuel Joseph Vizzotti One of the ways to improve the dissolution rate of poorly water-soluble drugs is to produce fine drug particles with increased surface area. This increase will lead to bioavailability enhancement. However, smaller drug particles are thermodynamically unstable and tend to aggregate or grow. Therefore, proper formulation and process parameters must be chosen to keep the particles small. In this study, fine drug particles of two model drugs, fenofibrate and ibuprofen, are prepared by the melt emulsification technique. The influence of suspension formulation (i.e., the inclusion of polymers and surface-active agents) on particle stability is investigated. Moreover, different agitation techniques during cooling are studied for their impact on the physical stability and recrystallization of molten drug particles. The use of both nonionic surfactant Pluronic F68 and high-intensity ultrasound during cooling produces fenofibrate and ibuprofen suspensions with enhanced short-term physical stability. The optimized fenofibrate suspension is blended with hydroxypropyl methylcellulose film solution and cast into a solid strip film by oven drying. The film is characterized by redispersion and by dissolution rate. Particles are recovered from the films in de-ionized water within 5 minutes with no size increase, and a marked increase in dissolution rate is observed in comparison to as-received particles. The feasibility of incorporating stable drug particles produced by melt emulsification into strip films and consequent enhancement of particle recovery and dissolution rate from these films are successfully demonstrated. PRODUCTION OF STABLE BCS CLASS II DRUG SUSPENSIONS BY MELT EMULSIFICATION AND SUBSEQUENT INCORPORATION INTO POLYMER STRIP FILMS by Emanuel Joseph Vizzotti A Thesis Submitted to the Faculty of New Jersey Institute of Technology in Partial Fulfillment of the Requirements for the Degree of Master of Science in Chemical Engineering Department of Chemical, Biological, and Pharmaceutical Engineering
Star Resist Roughness CNF Project # 386-90 Principal Investigator ( s ) :

Linear and star-shaped ArF photoresists were prepared, and lithographic comparisons were performed. An oligo-initiator, based on saccharose, forms the core of the star shaped photoresist, from which three standard ArF photoresist monomers, α-gamma butyrolactone methacrylate (GBLMA), methyl adamantyl methacrylate (MAMA) and hydroxyl adamantyl methacrylate (HAMA) were polymerized. Conditions were adjusted to obtain a low polydispersity, 6 kg/mol star polymer with a degree of polymerization of approximately five mers per arm. For comparison, a linear photoresist control was prepared using the same scheme. The star resist architecture was found to improve roughness without reducing sensitivity or resolution.