Miracle-dz/UniFAR-FTUs huggingface dataset:
Implementierung eines Fast-Track-Programmes . Herausforderungen und Lösungsansätze

Background. For more than a decade the evolving concept of fast track surgery has been implemented, predominantly in colorectal surgery. The practice of fast track surgery has yielded excellent results concerning reduction of postoperative complications and hospital stay and has been shown to increase patient satisfaction; however, several studies have shown a sometimes alarmingly low rate of implementation of the individual fast track measures and the rate is a maximumof 44%. Objective. In this review, obstacles for implementation of fast track surgery are investigated. Advice is given on possible solutions to circumvent obstacles and facilitate successful establishment of multimodal recovery protocols in individual institutions. Material and methods. The current international literature is critically evaluated and discussed with a particular focus on prospective clinical trials and expert recommendations. Results. The reasons for a lack of adherence to fast track surgery principles have been shown to be multifactorial. Time-consuming expenditure, logistic difficulties, lack of support by colleagues as well as limitations in the healthcare system and patient-dependent factors appear to complicate implementation of fast track programs. Conclusion. Successful implementation and long-term perpetuation can be achieved only by an interdisciplinary team with a low level hierarchy, continuous training and a positive feedback culture. An early inclusion and clarification of personnel and patients should be firmly integrated into the fast track concept. This results in a higher satisfaction of patients and personnel and subsequently stronger adherence to the fast track concept.
Authentification révocable pour la vérification basée texture d'empreintes digitales

The challenges during the deployment of biometric systems are numerous. We have to take into account performance, privacy, security and acceptability issues. In this context, we developed an authentication system using fingerprints whose extraction phase of the representative model breaks up into two stages. In the first stage, a vector characteristic of the fingerprint image is derived by using a Gabor filterbank. A detection process of the area of interest is operated beforehand. During the second stage, the characteristic vector is plunged in a salting scheme by using a secret key K. The model thus generated is a binary vector called BioCode. Only the BioCode will be registered for the recognition. The BioCode thus obtained offers an elegant solution to the mentioned problems before as our phase of tests proves it.
Hierarchy Website Fingerprint Using N-gram Byte Distribution

According to www.internetlivestats. com, there are over 1 billion websites on the world wide web (WWW) today while in 1991, there were only one single website. Websites classification based on traffic analysis has become a difficult problem due to the large number of websites within the internet. All the proposed approaches in the literature could not classify more than 100 websites which is a very trivial number compared to the total number of websites over the internet. In this paper, a two-level websites’ classification technique is proposed. At the first level, the traffic is classified to a general category such as sports, news, social, healthy, education, etc. Then, for further information the packet could be classified within the same category to identify from which websites the packet came.
Shaping Speech Patterns via Predictability and Recoverability.

Recoverability refers to the ease of recovering the underlying form—stored mental representations— given a surface form—actual, variable output signals (e.g., [Dæt^, Dæth]→ /Dæt/ ‘that’). Recovery can be achieved from phonetic cues explicitly present in the acoustic signal or through prediction from the context. However, recoverability can be compromised when the information in the signal is insufficient or the predictability in a given context is not high enough. The purpose of this dissertation is to investigate through experiments and computational modeling how phonotactic predictability in a given context affects (i) the amount of information present in the signal during production, (ii) the attention paid to the information during perception, and (iii) how reliance on phonotactics and phonetic cues might be learned. The language in focus is Japanese, a language well-known for its CV phonotactic preference, and the process of high vowel reduction, which often results in consonant clusters that violate this phonotactic restriction. The results suggest that language users prioritize predictability during speech processing, with phonetic-cue interpretation applying when predictability is not reliable enough.
Quelques réflexions sur le double insu Some reflexions about double blind

MOTS CLÉS Essai clinique randomisé ; Rupture du double insu ; Effets indésirables ; Effet placebo Résumé L’essai clinique randomisé contre placebo et en double insu est le meilleur moyen actuel de prouver l’efficacité clinique spécifique des médicaments. Pour cela, la procédure double insu, quand elle est éthiquement et techniquement réalisable, est une condition indispensable à la validité des résultats et à l’attribution causale de la différence observée entre les deux groupes à l’effet pharmacologique du médicament. Or, il apparaît qu’en pratique, les malades et les investigateurs peuvent deviner qui reçoit le médicament et qui reçoit le placebo, par exemple, en raison de la survenue d’effets indésirables plus fréquents chez les malades qui reçoivent le médicament. Ce phénomène, connu sous le nom de « rupture de l’insu », constitue alors un biais méthodologique impossible à éviter parce qu’il est inséparable de l’effet du médicament. Mais l’impact de cette rupture de l’insu « inévitable » reste à préciser. Si l’on peut raisonnablement penser qu’elle peut modifier les symptômes subjectifs comme l’anxiété ou la douleur par auto ou hétérosuggestion, son influence sur des critères objectifs reste à démontrer. © L’Encéphale, Paris, 2008.
2 Distinctive Immunological Functions of HLA-G

HLA-G is a non-classical HLA class Ib molecule belonging to the Major Histocompatibility Complex (MHC) located on the short arm of chromosome 6. The tissue-restricted distribution of HLA-G, the low polymorphism in the coding region, the fact that HLA-G primary transcript is alternatively spliced in seven isoforms, and the inhibitory action on immune cells, constitute four hallmarks of HLA-G, which distinguish it from other HLA class I molecules (Carosella et al., 1999). In healthy conditions, a basal level of HLA-G gene transcription is observed in most cells and tissues. However, translation into HLA-G protein is restricted to trophoblasts at the fetal-maternal interface (Carosella et al., 2003), and in adults, to thymic epitelial, cornea, mesenchymal stem cells (MSCs), nail matrix, pancreatic- cells, erythroid and endothelial precursors. HLA-G can be also neo-expressed in pathological conditions including malignant transformation, viral infections, inflammatory and autoimmune diseases, and allogeneic transplantation (Carosella, 2011).
THE ENTREPRENEURIAL JOURNEY OF VENTURE CREATION: RESHAPING PROCESS AND SPACE

espanolLas oportunidades emprendedoras y el proceso emprendedor se han entendido durante mucho tiempo como la base y el corazon del emprendimiento. En este articulo, utilizando el pensamiento sistemico y un enfoque sistemico, reformamos el modelo dinamico de etapas del proceso emprendedor para crear un metodo novedoso para la configuracion y las metricas de progresion del viaje emprendedor. Con este fin, hemos justificado que la madurez del proyecto se corresponde con la dimension generalizada que caracteriza el viaje emprendedor en la escala temporal. Hasta el lanzamiento de la empresa, la madurez percibida (por el empresario) de la empresa es la que describe la progresion del viaje emprendedor. Los artefactos generados dentro de las etapas del proceso emprendedor sirven como marcadores de la progresion del viaje. Tambien suponemos la combinacion del caracter discreto y continuo de la trayectoria del viaje emprendedor entre los confines que delimitan los corredores del espacio de oportunidad. Este articulo contribuye a los enfoques existentes que facilitan una mejor comprension del viaje emprendedor y los conceptos de proceso al examinar las interconexiones entre el proceso emprendedor, el viaje, la madurez de la empresa, el tiempo y el espacio. EnglishAbstract The author develops further technology-based entrepreneurial journey and process concepts and models as well as defining the space of opportunity development between of the edges: Discovery & Exploitation, Arbitrage & Innovation and Existing & Created Opportunities. For that, new stage model of the entrepreneurial process will be introduced in the next section followed by a description of the entrepreneurial journey based on that. From the analysis of objectivist and constructivist approaches to opportunities, the ways are deduced how entrepreneurs learn to apply and develop entrepreneurial opportunities. As a result, the framework of the HTSF entrepreneurial journey is presented. The main value of the paper is the development further entrepreneurial journey, the entrepreneurial process and entrepreneurial opportunity (corridor) concepts for technology entrepreneurship (HTSFs) and suggestion a framework for further empirical validation. Keywords: entrepreneurship; entrepreneurial process; high-tech ventures; new venture creation; technology entrepreneurship
PHYSICAL PROPERTIES AFFECTED BY SOIL PLANKING AND ROOT GROWTH OF COTTON ( GOSSYPIUM HIRSUTUM L . )

In the South East Anatolia region of Turkey as well as in many parts of world, soil planker is used to level and firm the soil prior to planting of cotton (Gossypium hirsutum L.) at least four times. However, excessive soil compaction due to using of planker can increase soil strength and hamper root growth. This study aimed to investigate the effects of soil planking on soil physical properties, the root growth of cotton and the density of weed species. In this purpose, a field experiment was carried out at different pass numbers of a planker by using a randomized block design with three replications in 2018. The results showed that penetration resistance was increased by the pass number of the planker at 015 cm soil depths. While soil planking increased the soil moisture content at 15 cm soil depth, it reduced the soil temperature. Multiple passes of planker decreased the root length and dry root weight of cotton. Soil planking levels differently influenced the density of weed species. Consequently, it can be said that the planking of soil before cotton seeding may influence the root growth and the density of weed species due to changing the physical properties of soil.
Talent Attraction Strategy and Employees ’ Productivity in Private Sugar Companies in Kakamega County , Kenya

Organizations that wish to be successful in this highly competitive world are the ones that systematically and proactively take necessary measures to ensure that they attract the best talented workforce. This study is aimed at determining the effect of talent attraction strategy on employees’ productivity in private sugar companies in Kakamega County. The study used cross-sectional survey research design. A stratified sampling and simple random sampling technique was also employed to enable the researcher to select the respondents from Butali and West Kenya private sugar companies in Kakamega County. The study was conducted between January 2016 to August, 2016. The target population was made up of 320 respondents which composed of 70 managers and 250 operative level employees’. A sample size of 178 respondents was selected out of which 133 respondents completed and returned the questionnaires leading to a response rate of 74.72%. Interview schedule and questionnaires were used for data collection. Validity and Reliability of research instruments was guaranteed by a test re-test method. The computed Cronbach’s alpha reliability of the research instrument was 0.834 which is acceptable in social research because it is above acceptable Cronbach’s alpha of 0.7. The data collected was analyzed using descriptive and inferential statistics with the aid of Statistical Package for Social Sciences (SPSS) version 20. Spearman’s rank-order correlation and simple linear regression models were used to test for relationships between the study variables. Research findings were presented in the form of frequency distribution tables, pie charts, and percentages. The study found that talent attraction strategy had a positive and significant relationship on employees’ productivity. It is recommended that organizations should put in place and implement relevant recruitment, selection and placement programmes so as to attract prospective productive employees.
In Search For New p 53 Regulated Genes

Mpagi, Meldrick. M.S., Department of Biochemistry and Molecular Biology, Wright State University, 2008. In Search For New p53 Regulated Genes. The p53 tumor suppressor protein has the ability to transactivate its target genes whose gene products are involved in carrying out cell cycle arrest, apoptosis, DNA repair, and senescence. Here, I report that two genes may be p53 regulated. Utilizing a microarray method to search for novel p53 target genes, I was able to identify a possible transcriptional target of p53 being solute carrier family 1a1 (SLC1a1). Along with that finding I also identified an E2F-target gene, minichromosome maintenance 10 (MCM10), as being p53 regulated. Gene expression profiling of MCF7 breast cancer cells treated with RNAi targeting Hdm2 and HdmX in order to reactivate p53 led to increased SLC1a1 transcript levels. DNA damage experiments in several cell lines and along with a p53 overexpression experiment established that p53 activation unexpectedly lead to no transcriptional increase in SLC1a1 expression. The results suggest that SLC1a1 is not a transcriptional target of p53 and may have been a false positive result from the microarray experiment.
BASELINE ADJUSTMENT FOR STATISTICAL EFFICIENCY ON CLINICAL CONTROLLED TRIAL

In a clinical controlled trial involving repeated measures of continuous outcomes such as quality of life, distress, pain, activity level at baseline and after treatment, the possibilities of analyzing these outcomes can be numerous with quite varied findings. This paper examined four methods of statistical analysis using data from an outcome study of a clinical controlled trial to contrast the statistical power on those with baseline adjustment. In this study, data from a CCT with women with breast cancer were utilized. The experiment (n=67) and control (n=74) were about equal ratio. Four method of analysis were utilized, two using ANOVA for repeated measures and two using ANCOVA. The multivariate between subjects of the combined dependents variables and the univariate between subjects test were examined to make a judgement of the statistical power of each method. The results showed that ANCOVA has the highest statistical power. ANOVA using raw data is the least power and is the worst method with no evidence of an intervention effect even when the treatment by time interaction is statistically significant. In conclusion, ANOVA using raw data is the worst method with the least power whilst ANCOVA using baseline as covariate has the highest statistical power to detect a treatment effect other than method. The second best method as shown in this study was in using change scores of the repeated measures. (JUMMEC 2009; 12 (1): 31-34)
Filamentous Hemagglutinin and Pertactin of Bordetella pertussis in BALB / c Mice View project Diagnosis of Candida Species Isolated from Patients with Vaginal Candidiasis and Healthy Individuals Based on Clinical Symptoms and Paraclinical Evidences View project

Opioid system plays a significant role in pathophysiological processes, such as immune response and impacts on disease severity. Here, we investigated the effect of opioid system on the immunopathogenesis of respiratory syncytial virus (RSV) vaccine (FI-RSV)-mediated illness in a widely used mouse model. Female Balb/c mice were immunized at days 0 and 21 with FI-RSV (2 × 106 pfu, i.m.) and challenged with RSV-A2 (3 × 106 pfu, i.n.) at day 42. Nalmefene as a universal opioid receptors blocker administered at a dose of 1 mg/kg in combination with FI-RSV (FI-RSV + NL), and daily after live virus challenge (RSV + NL). Mice were sacrificed at day 5 after challenge and bronchoalveolar lavage (BAL) fluid and lungs were harvested to measure airway immune cells influx, T lymphocyte subtypes, cytokines/chemokines secretion, lung histopathology, and viral load. Administration of nalmefene in combination with FI-RSV (FI-RSV + NL-RSV) resulted in the reduction of the immune cells infiltration to the BAL fluid, the ratio of CD4/CD8 T lymphocyte, the level of IL-5, IL-10, MIP-1α, lung pathology, and restored weight loss after RSV infection. Blocking of opioid receptors during RSV infection in vaccinated mice (FI-RSV-RSV + NL) had no significant effects on RSV immunopathogenesis. Moreover, administration of nalmefene in combination with FI-RSV and blocking opioid receptors during RSV infection (FI-RSV + NL-RSV + NL) resulted in an increased influx of the immune cells to the BAL fluid, increases the level of IFN-γ, lung pathology, and weight loss in compared to control condition. Although nalmefene administration within FI-RSV vaccine decreases vaccine-enhanced infection during subsequent exposure to the virus, opioid receptor blocking during RSV infection aggravates the host inflammatory response to RSV infection. Thus, caution is required due to beneficial/harmful functions of opioid systems while targeting as potentially therapies.
Spatial offloading in multiple task monitoring

ABSTRACT Coordinating multiple tasks requires a high degree of cognitive control, and individuals with limited executive functions often show difficulties in everyday multitasking. We tested the hypothesis that demands on executive control can be alleviated by internally representing the temporal pattern of goals and deadlines as spatial relations. In two experiments, participants completed a multitasking session by monitoring deadlines of four clocks running at different rates, along with separate tasks of executive functioning and spatial ability. In Experiment 1, individual and gender-related differences in spatial ability (mental rotation) predicted multitasking performance, beyond the contributions of both the updating and inhibition components of executive functioning, and even when spatial cues were eliminated from the layout of the monitoring task. Experiment 2 extended these findings by showing that concurrent spatial load impaired task monitoring accuracy, and that these detrimental effects were accentuated when spatial abilities were compromized due to fluctuation in female sex hormones. These findings suggest that multiple task monitoring involves working memory-related functions, but that these cognitive control demands can be offloaded by relying on spatial relation processes.
introduced rocky intertidal barnacle Balanus glandula

The barnacle, Balanus glandula has recently invaded along the Pacific coast of eastern Hokkaido, Japan. To evaluate the direct and indirect effects of endemic seaweeds, barnacles, and invertebrate predators on the abundance of B. glandula on the rocky intertidal coast of eastern Hokkaido, we conducted a field experiment from June 2011 to October 2012 in which we manipulated the presence or absence of these factors. Seaweeds showed no significant effect on the abundance of B. glandula. The endemic barnacle Chthamalus dalli and the invertebrate predator Nucella lima reduced the abundance of B. glandula. However, the simultaneous influence of N. lima and C. dalli was compensative rather than additive, probably due to keystone predation. These findings suggest that competition by the endemic barnacle C. dalli and predation by the invertebrate predator N. lima decreased the abundance of B. glandula, but that N. lima predation on C. dalli weakened the negative influence of C. dalli on B. glandula. The implications of these findings are twofold: the endemic competitor and invertebrate predator may have played important roles in decreasing the abundance of B. glandula in natural habitats, and conservation of endemic invertebrate predators may be crucial to impede the establishment and survival of introduced barnacles in rocky intertidal habitats.
’ response to the reviewers ’ comments on “ Regional co-variability of spatial and temporal soil moisture-precipitation coupling in North Africa : an observational perspective ” by

The magnitude and sign of soil moisture precipitation :::::::::::::::::: moisture–precipitation : coupling (SMPC) is investigated using a probability-based approach and 10 years of daily microwave satellite data across North Africa at 1◦ horizontal scale. Specifically, the co-existence and co-variability of spatial (i.e. using soil moisture gradients) and temporal (i.e. using soil moisture anomaly) soil moisture effects on afternoon rainfall is explored. The analysis shows that in the semi-arid environment of the Sahel, the negative spatial and the negative temporal coupling relationships do not only co-exist, but are also dependent 5 of one another. Hence, if afternoon rain falls over temporally drier soils, it is likely to be surrounded by a wetter environment. Two regions are identified as SMPC "hot spots :::::::: hot-spots". These are the south-western part of the domain (7 15 :::: 7–15◦ N, 10◦ W 7 ::: W–7◦ E) with the most robust negative SMPC signal, and the South Sudanian region (5 13 :::: 5–13◦ N, 24 34 ::::: 24–34◦ E). The sign and significance of the coupling in the latter region is found to be largely modulated by the presence of wetlands and is susceptible to the amount of long-lived propagating convective systems. The presence of wetlands and an irrigated land area 10 is found to account for about 30 % of strong and significant spatial SMPC in North African domain. This study provides the first insight into regional variability of SMPC in North Africa, and supports potential relevance of mechanisms associated with enhanced sensible heat flux and meso-scale :::::::: mesoscale : variability in surface soil moisture for deep convection development.
Zbornik radova Fakulteta tehničkih nauka, Novi Sad

– This paper presents a real estate price prediction model using advertisement data. Real estate technical specifications, images and, if available, geographical coordinates are extracted from advertisements, acquired from a real estate advertising website. The coordinates are used to form location ratings. The images are used to train a neural network for the detection of a real estate's equipment on images.Three separate datasets for training the price prediction models were formed. The first dataset contains only technical specifications of the real estates, the second dataset also contains location ratings, while the third dataset contains location ratings and objects detected on images. These datasets were used to train different regression models for predicting real estate prices. The performances of the models, represented by their achieved R 2 scores, were compared in order to establish which model had the best performances. The best performing model was the GBT (Gradient Boosted Trees) model on the dataset with location ratings and detected objects, with an achieved R 2 score of 0.856.