Miracle-dz/UniFAR-FTUs huggingface dataset:
Chlorophyll-Mediated Changes in the Redox Status of Pancreatic Cancer Cells Are Associated with Its Anticancer Effects

Nutritional factors which exhibit antioxidant properties, such as those contained in green plants, may be protective against cancer. Chlorophyll and other tetrapyrrolic compounds which are structurally related to heme and bilirubin (a bile pigment with antioxidant activity) are among those molecules which are purportedly responsible for these effects. Therefore, the aim of our study was to assess both the antiproliferative and antioxidative effects of chlorophylls (chlorophyll a/b, chlorophyllin, and pheophytin a) in experimental pancreatic cancer. Chlorophylls have been shown to produce antiproliferative effects in pancreatic cancer cell lines (PaTu-8902, MiaPaCa-2, and BxPC-3) in a dose-dependent manner (10–125 μmol/L). Chlorophylls also have been observed to inhibit heme oxygenase (HMOX) mRNA expression and HMOX enzymatic activity, substantially affecting the redox environment of pancreatic cancer cells, including the production of mitochondrial/whole-cell reactive oxygen species, and alter the ratio of reduced-to-oxidized glutathione. Importantly, chlorophyll-mediated suppression of pancreatic cancer cell viability has been replicated in in vivo experiments, where the administration of chlorophyll a resulted in the significant reduction of pancreatic tumor size in xenotransplanted nude mice. In conclusion, this data suggests that chlorophyll-mediated changes on the redox status of pancreatic cancer cells might be responsible for their antiproliferative and anticancer effects and thus contribute to the decreased incidence of cancer among individuals who consume green vegetables.
SYSTEMIS AND METHODS FOR PLANNING A ROBOT GRASP THAT CAN WITHSTAND TASK DISTURBANCES

Int. C. G06F 7/00 (2006.01) G05B 9/18 (2006.01) B25, 9/16 (2006.01) B25J 9/00 (2006.01) U.S. C. CPC . B25.J 9/1612 (2013.01); B25J 9/0081 (2013.01); B25J 9/1605 (2013.01); B25J 9/1687 (2013.01); Y10S 901/02 (2013.01); Y10S 901/04 (2013.01) Field of Classification Search . 700/253, 19, 28, 97; 318/. 568.11, 568.12, 318/. 568.2: 701/98 See application file for complete search history. USPC (56) References Cited
Improving SAS Global Forum Papers

Just as research is built on existing research, the references section is an important part of a research paper. The purpose of this study is to find the differences between professionals and academicians with respect to the references section of a paper. Data is collected from SAS® Global Forum 2014 Proceedings. Two research hypotheses are supported by the data. First, the average number of references in papers by academicians is higher than those by professionals. Second, academicians follow standards for citing references more than professionals. Text mining is performed on the references to understand the actual content. This study suggests that authors of SAS Global Forum papers should include more references to increase the quality of the papers.
Biotic vs abiotic drivers of seedling persistence in a tropical karst forest

Question Quantifying the duration and drivers of seedling persistence is critical for understanding seedling dynamics and species coexistence in plant communities. In this study, we incorporated data from multiple seedling censuses to characterize patterns of seedling persistence in a tropical karst forest. Specifically, we evaluated the effects of density dependence, habitat heterogeneity, and recruitment timing on seedling persistence. Location A tropical karst forest in Taiwan. Methods Using data from 144 seedling plots censused every three months from 2007 to 2012, we examined persistence times of 6399 seedlings of 36 species. Seedling survival was estimated by the Kaplan-Meier method. Mixed effects Cox models were used to identify significant biotic (i.e., initial height, conspecific and heterospecific seedling and adult densities) and abiotic (i.e., mean elevation, convexity, slope, effective soil depth, and recruitment time) drivers of seedling persistence at the community, guild and species levels. Results At the community level, newly recruited seedlings had a median survival time of 6 months. Median survival time was higher for seedlings in the shade-tolerant guild compared to seedlings in the shade-intolerant guild (9 vs. 3 months). When all species were analyzed together, seedling persistence significantly increased with increasing initial size and soil depth and significantly decreased with increasing density of conspecific and heterospecific seedling neighbors. Drivers of seedling persistence tended to be guild- and species-specific, however negative effects of conspecific seedling neighbors were consistently detected in all models, indicating strong and pervasive conspecific negative density dependence. Significant effects of recruitment time, soil depth and convexity were revealed by guild- and species-specific models, suggesting abiotic niche differences. Conclusions This study highlights the importance of multiple ecological processes for seedling persistence. Both abiotic and biotic factors may play an important role in species coexistence in this forest via niche partitioning and negative density dependence. Among these factors, negative conspecific density dependence had the strongest and most consistent effect. In addition, soil depth played a key role in shaping seedling regeneration, likely through effects of soil moisture. Overall, this study contributes to a better understanding of the ecology of karst forests. Analyzing seedling persistence in karst forest expands our general understanding of forest dynamics and species coexistence in tropical forests as a whole, especially at sites with high spatial heterogeneity. This article is protected by copyright. All rights reserved.
BIRTH TRAUMA – OBSTETRIC VIEW PORODNA TRAUMA – OPSTETRI^KI POGLED

Birth trauma still remains an unavoidable and very actual obstetric issue. Nobody in delivery rooms can be completely protected from this obstetric complication. The focused meaning of the term that will be discussed here represents only physical injuries to the fetus / newborn and the mother. Those birth injuries usually happen as a consequence of an extreme intrapartal mechanical forces acting directly to bony and soft connective tissues of fetal or maternal organisms. All obstetric interventions are at some degree risky and there are no absolutely accurate solutions. Although birth traumas are most often connected with vaginal deliveries, children delivered by cesarean section are not totally protected from those injuries. The incidence of some birth traumas did not change significantly during time, while some other forms of injuries appear more rarely. There are several classifications of birth traumas as well as their main causes, but a new basic classification into objective and subjective causes of intrapartal injuries is very important from both the obstetrical and medico-legal points of view. The causes could be defined as objective, if they are commonly associated with an increased risk of fetal and maternal injuries, if the injuries are usually more frequent or almost always result from those specific delivery situations, and if they are independent or modestly dependent of obstetrician’s experience. All intrapartal unfortunate events associated with rare and prenatally undetected diseases or pathological fetal conditions that are directly attributable to development of injuries despite correctly performed obstetric interventions, are also included in the same group of causes. Subjective causes of birth injuries most often involve birth injury incidents as consequence of incorrect, negligent and superficial obstetric procedures in otherwise low-risk clinical situations. Birth injuries can be mild and transitory with a good outcome, but also tragic and devastating events with lethal consequences. Apart from perinatological significance, which comes from its influence on peripartal mortality and morbidity, birth trauma is very important from medico-legal aspects. Medico-legal and financial consequences are important to those children, their parents, medical staff, and the whole society. That is why the effective primary and secondary prevention of birth injuries are needed unconditionally. Obstetrician’s correct and timely decisions and measures can greatly reduce birth traumas and their serious consequences.
Plausible Biomedical Consequences of Acupuncture Applied at Sites Characteristic of Acupoints in the Connective-Tissue-Interstitial-Fluid System

Traditional Chinese Medicine (TCM) has been in existence for several thousand years, based on the general philosophy that the physiological states of a healthy body are kept balanced. Pathogenesis occurs when such a balance is upset. There have been more and more studies using modern biomedical techniques and animal models on the clinical benefits of herbal TCM in the recent two decades. Fruitful developments have been made on the analysis of the biochemical ingredients of the herbs considered. However, standardization of ingredi‐ ents of the herbs, the concept of “complex recipe” and a modern theory of herbal TCM de‐ scribed in terms of modern western medicine conception, are still issues of discussion while herbal TCM progresses.
An Epidemic Perspective on the Cut Size in Networks

An epidemic spreads over the network via infectious links between healthy and infected nodes. The rate of increase in the number of infected nodes depends on the number of infectious links, called the cut size. After reviewing results on the cut size, its average and variance are computed in a simpli ed case, where each node has equal infection probability v, independent of all the other nodes. Although the simpli ed case is approximate for an epidemic process, high degree variance graphs are shown to di¤use information and diseases in the fastest and most bursty way. Moreover, variations of the cut size divided by the mean cut size decrease with v and are minimum for any graph at v = 1 2 . 1 Introduction Motivated by its crucial role in the spead of epidemics on networks as reviewed below, we investigate the cut size, which equals the number of links between two partitions of a graph. The determination of and tight bounds on the cut size continue to play a central role in graph theory. Here, we rst review in Section 2 the state of the art about the cut size from an epidemic perspective, where a viral item propagates from infected nodes towards healthy nodes through links of the cut-set. Additional results are given in the Appendices. In Section 3, we provide a probabilistic estimate for a simpli ed case, where all nodes possess a same probability to belong to the infected partition. We consider an unweighted, undirected graph G containing a setN of N nodes (also called vertices) and a set L of L links (also called edges). The topology of the graph is represented by a symmetric N N adjacency matrix A. In a SIS epidemic process on G, the viral state of a node i at time t is speci ed by a Bernoulli random variable Xi (t) 2 f0; 1g: Xi (t) = 0 for a healthy, but susceptible node and Xi (t) = 1 for an infected node. A node i at time t can be in one of the two states: infected, with probability vi(t) = Pr[Xi(t) = 1] or healthy, with probability 1 vi(t), but susceptible to the infection. We assume that the curing process per node i is a Poisson process with rate and that the infection rate per link is a Poisson process with rate . Obviously, only an infected node can infect its direct neighbors, that are still healthy. Both the curing and infection Poisson process are independent. Faculty of Electrical Engineering, Mathematics and Computer Science, P.O Box 5031, 2600 GA Delft, The Netherlands; email : P.F. A.VanMieghem@tudelft.nl
REVIEW OVER HOLE HEALING TECHNIQUES IN WIRELESS SENSOR NETWORKS

Improving coverage and connectivity is a very important issue in wireless sensor networks. The unattended or uncovered region in a sensing field is called a coverage hole. A coverage hole impacts the performance of the wireless sensor network, disconnects the network topology and causes delay in data transmission. These coverage holes can be healed randomly or each hole can be assigned a priority value for healing. In this paper we will discuss about various hole healing strategies and their mechanisms.
FACIAL RECOGNITION: INTRASPECIFIC VARIATION AND DEVELOPMENT OF SPECIALIZATION IN POLISTES FUSCATUS, A MODEL SYSTEM

Specialized face learning, the ability to learn and remember faces better than other visual stimuli, occurs across a wide range of social animal taxa. However, the ontogeny of specialized face learning, specifically whether it develops due to innate, learned, or a combination of innate and learned factors, remains debated in the literature. Empirical data on face specialization has supported all three hypotheses, yet conflicting methodologies and data interpretations complicate our understanding of the ontogeny of face specialization. In this study, we use Polistes fuscatus (paper wasp), a system with intraspecific variation in developmental environment (innate) and experience (learned), to test the ontogeny of specialized face learning. Our results support the combination hypothesis for the development of specialized face learning, with both innate and learned factors needed to fully explain intraspecific variation in face specialization. Wasps with better early nutritional environment (gynes) learned to discriminate faces more accurately than wasps with poorer nutrition during early development (workers), perhaps due to innate variation in neural structures. Furthermore, older wasps (foundresses) learned faces faster than other stimuli, while younger wasps (gynes) showed no difference in rate of learning between stimuli. We posit that older wasps have greater specialization for learning faces than younger wasps due to higher levels of facial exposure throughout life. Controlled manipulations of early development and adult experience will be useful to provide a more detailed analysis of the ontogeny of specialized face learning. Our results, which suggest that the combined effects of learned and innate factors are necessary to explain the ontogeny of specialized face learning, may be generalizable to all social animals.
Sparse MDMO: Learning a Discriminative Feature for Micro-Expression Recognition

Micro-expressions are the rapid movements of facial muscles that can be used to reveal concealed emotions. Recognizing them from video clips has a wide range of applications and receives increasing attention recently. Among existing methods, the main directional mean optical-flow (MDMO) feature achieves state-of-the-art performance for recognizing spontaneous micro-expressions. For a video clip, the MDMO feature is computed by averaging a set of atomic features frame-by-frame. Despite its simplicity, the average operation in MDMO can easily lose the underlying manifold structure inherent in the feature space. In this paper we propose a sparse MDMO feature that learns an effective dictionary from a micro-expression video dataset. In particular, a new distance metric is proposed based on the sparsity of sample points in the MDMO feature space, which can efficiently reveal the underlying manifold structure. The proposed sparse MDMO feature is obtained by incorporating this new metric into the classic graph regularized sparse coding (GraphSC) scheme. We evaluate sparse MDMO and four representative features (LBP-TOP, STCLQP, MDMO and FDM) on three spontaneous micro-expression datasets (SMIC, CASME and CASME II). The results show that sparse MDMO outperforms these representative features.
D.B.E. - The Digital Business Ecosystem

C1 IBM IBM Business Consulting Services BE C2 LSE London School of Economics UK C3 T6 T6 scarl IT C4 SUN Sun Microsystems Iberica ES C5 FZI Forschungszentrum Informatik DE C6 ICL Imperial College London UK C7 IESE IESE Business School Universidad de Navarra ES C8 INTEL INTEL Ireland IE C9 ISUFI Institute for Advanced Interdisciplinary Studies University of Lecce IT C10 TUC MUSIC Technical University of Crete EL C11 STU Fachhochschulgesellschaft Salzburg AT C12 3vSOFT 3vSOFT IT C13 TTC Tampere Technology Center FI C14 TCD Trinity College Dublin – Computer Science Dep. IE C15 UBHAM University of Birmingham Computer Science Dep. UK C16 UCE University of Central England UK C17 UniS University of Surrey UK C18 ITA Aragon Technological Institute ES C19 CENSIS Centro Studi Investimenti Sociali IT C20 WIT Waterford Institute of Technology IE
Hierarchy Attenuating/Enhancing Organizational Environments and Intergroup Attitudes: Relationship of Racism, Classism, and Sexism in Multiracial and Monoracial Churches of the United States

As Yancey (2003) has pointed out, the intentional character of racially integrated churches tends to lessen the social distance between Whites and minorities. The purpose of this study is to examine how racially hierarchy-attenuating and hierarchy-enhancing environments affect classism and sexism attitudes among congregations. The finding shows that multiracial churches promote H-A environment for class and race diversity, but not for gender equality. The class and race diversity is affected by organizational structure; on the other hand, gender equality is influenced by theologies. This study finds the answers to this discrepancy from the effect of biblical teachings on classist and sexist attitudes and the cumulative effect of structured domination of women.
STEERING A MOBILE ROBOT: SELECTION OF A VELOCITY PROFILE SATISFYING DYNAMICAL CONSTRAINTS

We present an open loop control design allowing to steer a wheeled mobile robot along a prespecified smooth geometric path, minimizing a given cost index and satisfying a set of dynamical constraints. Using the concept of “differential flatness,” the problem is equivalent to the selection of the optimal time parametrization of the geometric path. This parametrization is characterized by a differential equation involving a function of the curvilinear coordinate along the path. For the minimum time problem, as well as for another index (such as the maximum value of the centripetal acceleration) to be minimized over a given time interval, the problem then reduces to the optimal choice of this function of the curvilinear coordinate. Using spline functions interpolation, the problem can be recast as a finite parameter optimization problem. Numerical simulation results illustrate the procedure.
Altered Placental Tryptophan Metabolism: A Crucial Molecular Pathway for the Fetal Programming of Neurodevelopmental Disorders

Abstract : Maternal infections in humans increase the risk for autism spectrum disorders (ASD) in the offspring. In rodents, maternal infections cause behavioral, histological and transcriptional changes in adult offspring that are consistent with those seen in ASD. However, the anatomical and molecular pathways through which inflammation alters fetal brain development are not well understood. Serotonin (5-HT), which is synthesized from the essential amino acid tryptophan (TRP), is a trophic factor for the fetal brain before it acts as a neurotransmitter. In particular, 5-HT signaling modulates fetal brain wiring mechanisms and its disruption at early stages of pre- and postnatal development has long-term consequences on adult brain function and behavior. Thus, 5-HT is thought to be a critical mediator of the fetal programming of mental disorders such as ASD that appear later in life. In early pregnancy the placenta converts maternal TRP to 5-HT, through the tryptophan hydroxylase 1 (TPH1) pathway, thereby providing a source of the amine for the fetal brain. Therefore altering maternal TRP metabolism in the placenta, and consequently placental 5-HT synthesis, may directly affect fetal brain development and constitute a new molecular pathway for the fetal programming of mental disorders. The goal of this project is to characterize the impact of inflammation during pregnancy on placental TRP metabolic pathways and the consequences on fetal brain development
Lesões intraepiteliais escamosas cervicais graus 1 e 2: valor de uma classificação morfológica alternativa e do estudo imuno-histoquímico com p16 na predição do desfecho clínico

Introduction: Diagnostic reproducibility and determination of prognostic factors in cervical intraepithelial neoplasias grades 1 and 2 are still relevant problems in the daily practice of gynecological histopathology. Objective: To correlate the value of morphological reclassification and of p16 immunoexpression in cervical intraepithelial neoplasias grades 1 and 2 with clinical outcome. Materials and methods: Sixty-six patients were included (34 with cervical intraepithelial neoplasia grade 1, and 32 with grade 2); an immunohistochemical study with p16 and reclassification according to the Lower Anogenital Squamous Terminology (LAST) Consensus and by the alternative proposal of Herfs and Crum were done; unfavorable outcome was defined as a subsequent histologic diagnosis of cervical intraepithelial neoplasia grade 3 or invasive squamous cell carcinoma. Results: We observed superior performance of the alternative morphological classification (p = 0.002) to determine unfavorable outcome. We also detected superior performance of p16 in the same determination (p = 0.002). Conclusion: The use of an alternative morphological classification is promising; in the context of the use of immunohistochemical antibodies as biomarkers, p16 showed good sensitivity and negative predictive value in the determination of cases in which the outcome was unfavorable.
When research moves in – the diffusion of evidence-based practice in Swedish social work

Skillmark, M. , Denvall, V. (2016) When research moves in: the diffusion of evidence-based practice in Swedish social work. In: Francisco Branco, Inês Amaro, Cristina Albuquerque, Maria Isabel Santos, Ana Oliveira, Inês Guerra (ed.), 6th European Conference for Social Work Research: Reflective social work practices in contemporary societies : dialogues and new pathways between praxis and research : Book of Abstracts & Prgoramme Book (pp. 242-243).
Basic Interests: The Importance of Groups in Politics and in Political Science by Frank R. Baumgartner and Beth L. Leech

doned organized labor. He also tolerated racial discrimination in government, in contrast to his successor, Harry Truman. Instead of offering a nuanced account of FDR’s political strategy, the book offers an apologia. Bold Relief offers a useful and often insightful overview of the origin of and limits to U.S. social policy. But by taking the reformist policies of the late 1930s as the benchmark for U.S. social policy, the author marginalizes the relevance of his own analysis for a broader understanding of U.S. social policy.