Miracle-dz/UniFAR-FTUs huggingface dataset:
Metodología para la medición de micro topografías en canales de laboratorio con un sensor de movimiento

RESUMEN Un aspecto importante de la modelación física en hidráulica fluvial es la medición de las geometrías de los procesos de erosión y sedimentación. Actualmente la técnica más popular para realizarlo utiliza distanciómetros laser, las cuales tienen una precisión de ± 1 mm y un costo de como US$ 150. Como alternativa se presenta el desarrollo de una novedosa técnica para realizar relevamientos en 3 dimensiones (3D) con un sensor de movimiento en canales de laboratorio a lecho móvil. Utilizamos Xtion Pro de ASUS, diseñado originalmente para juegos de video. La técnica propuesta presenta un alto rendimiento comparado con metodologías tradicionales, ya que el volumen de información es sustancialmente mayor y el tiempo que demanda la tarea es menor. La precisión de los resultados es la misma. Bajo 60 cm de distancia, la resolución espacial y de profundidad aproxima 1 mm y las imágenes cubren un área de 64 × 48 cm2, con velocidad de captura hasta 30 cuadros por segundo (fps). Implementar la técnica permite la generación de modelos digitales del terreno a un muy bajo costo, los cuales son de gran utilidad en la hidráulica fluvial. La técnica propuesta permite realizar diversos análisis, tales como estudios de las formas de fondo, volúmenes de sedimento erosionados o depositados, el trazado de líneas preferenciales de escurrimiento y más, que pueden ser manipulados utilizando Sistemas de Información Geográfica (GIS) o ser entrada en numerosos modelos numéricos. Se ilustrará el procedimiento para la utilización de estos equipos en relevamiento de laboratorios, particularmente aplicados a canales compuestos con material aluvial, sometidos a procesos de erosión.
Chordoma in a Thoracic Vertebra

Chordoma is a tumor which arises from remains of the notochord. These remnants are often present in the sacrum and clivus but are seldom encountered in the cervical, thoracic, and lumbar vertebrae. Some authors SCHWABE, for'instance definitely deny the existence of such remains in any other part of the spinal column than in the sacrum. SCHMORL, however, has found cells deriving from the notochord in all sections of the vertebral column. The type of tumor in question must be regarded as malignant, since it grows by infiltration, and shows a tendency to recur, and since it is often accompanied by metastasis. The literature contains many reports on the subject. In Germany, ANDLER and SCHMINCKE described 20 cases in 1923 and COENEN 47 cases in IlJ25. In England, 55 cases were reported by STEWART and MORIN in 1926, and in France, 62 cases were surveyed by CORSY and SURMONT in 1927. In America, MABREY reviewed in 1935 150 cases from the entire literature. All these authors asserted that the tumors occur most frequently in the clival and sacral regions. In MABREY'S material, 49 of the tumors arose in the cranium and 87 in the sacrum; the remaining 14 originated in the cervical, thoracic, or lumbar vertebrae. GUTHERT discovered in the literature reports of 21 cases of chordoma arising in the cervical, thoracic, or lumbar vertebrae, and of these, 5 had their origin in the thoracic vertebrae. Thus, the statement that remnants of the notochord cannot exist in these sections of the spinal column, evidently does not coincide with the facts. In all probability, when the first mention of the disease was made, the tumors were localized in the sacrum or the clivus, and the possibility that they might arise in some other part of the vertebral column was not taken into consideration. Chordoma originating in the thoracic. vertebrae is still a rare occurrence, however, and it may be of interest to describe a case of this type of tumor now being treated at the Sahlgrenska Hospital.
Standards make the GIH possible

Technical telecommunications standards form the foundations of the global information highway (GIH). Yet an understanding of the taxonomy of technical standards, the value and relationship of the different fora developing standards, even the need for standards at all, remain elusive. With the global effect of the GIH, technical telecommunications standards are no longer a minor aspect of society. The International Telecommunications Union, as the leading telecommunications standards-making authority, in conjunction with the many other fora developing and contributing to telecommunications standards, needs to offer more than technical standards direction. The telecommunications standards-making community should add its own more considered view of the GIH to the current commentary from publications, politicians, and pundits.
Task Graph Performance Bounds Through Comparison Methods

When a parallel computation is represented in a formalism that imposes seriesparallel structure on its task graph, it becomes amenable to automated analysis and scheduling. Unfortunately, its execution time will usually also increase as precedence constraints are added to ensure series-parallel structure. Bounding the slowdown ratio would allow an informed tradeoff between the benefits of a restrictive formalism and its cost in loss of performance. This dissertation deals with series-parallelising task graphs by adding precedence constraints to a task graph, to make the resulting task graph series-parallel. The weak bounded slowdown conjecture for series-parallelising task graphs is introduced. This states that the slowdown is bounded if information about the workload can be used to guide the selection of which precedence constraints to add. A theory of best series-parallelisations is developed to investigate this conjecture. Partial evidence is presented that the weak slowdown bound is likely to be 4/3, and this bound is shown to be tight.
Current and investigational treatments for spinal muscular atrophy

Introduction: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder in humans characterized by impaired motor neuron function resulting in muscle weakness and atrophy. It is clinically classified into four main types based on age of onset and clinical severity. SMA is caused by a reduced level of functional survival motor neuron (SMN) protein. The physiological relevance of SMN has been implicated in pre-mRNA splicing and its critical involvement in cellular processes in the axons of motor neurons. Areas covered: At present, no effective treatment is available for SMA. Current therapeutic strategies for treating SMA focus on SMN expression augmentation and the development of neuroprotective agents. Preclinical successes from approaches including gene therapy, antisense oligonucleotides, small molecule drugs and stem cell technology have been described and their clinical relevance has been discussed. However, clinical trials of drug compounds conducted hitherto have not shown conclusive evidence to support any particular type of drug compound as an effective intervention for curing SMA patients. Expert opinion: Among the current therapeutic strategies, vector-based gene therapy is one of the most promising candidates for treating SMA. Its success and safety demonstrated in preclinical studies in mouse models and non-human primates have given us optimism in translating the technology into the clinic. Major challenges yet to be addressed are the efficient penetration of the blood-brain-barrier, the route of delivery that maximizes global distribution with a minimal invasive technique to the patient and the timing of the treatment for patients to achieve the highest therapeutic benefits.
A Logical Framework for Integrating Software Models via Refinement

We propose the development of an institution-based framework within which software models can be combined not only at different levels of abstraction but across multiple formalisms. Event-B is an industrial-strength formalism that supports refinement, we envisage that the construction of an institution for Event-B, EVT, will not only increase the modularity of Event-B specifications but also provide a foundation for the interoperability of Event-B with other formalisms.
Health needs of women in the postpartum

Objective: To distinguish women health needs in the postpartum and understand them under the sociocultural look genre. Methods: Qualitative research in two areas of the Health Strategy Cuiabá family, Mato Grosso, in the year 2012, with thirteen women through semi-structured interviews and content analysis. Results: The participants prioritize the needs to promote wellbeing and security to the child and to reconcile assumed housekeeping and daily rhythms. Put in the background emotional-social, affective-marital needs, relieving burdens on business, organic, among others, but wish, albeit in conflicting and contradictory way, recovering autonomy/freedom which had before maternity to take care of itself. Conclusions: Need the support of health services to recognize the experience and understanding the sociocultural aspects involved in their needs and ways to care for themselves incorporated.
The double burden of malnutrition : a review of global evidence

The Double Burden of Malnutrition (DBM) is the coexistence of both under nutrition and over nutrition in the same population across the life course. 'Across the life course' refers to the phenomenon that under nutrition early in life contributes to an increased propensity for over nutrition in adulthood. The DBM affects all countries, rich and poor, and is a particular concern in countries with high stunting rates. The consequences of the DBM are enormous; early life under nutrition is an underlying cause associated with about a third of young child deaths. Among the survivors who become stunted during the first two years of life, their capacity to resist disease, to carry out physical work, to study and progress in school, are all impaired across the life course. Later in the life course, diet and nutrition, and especially obesity, are important underlying causes of many Non-Communicable Diseases (NCDs), including hypertension, diabetes, cancer, stroke, and ischemic heart disease. The causes of the DBM are related to a series of changes occurring in the world called the nutrition transition, the demographic transition, and the epidemiological transition of countries. The variables associated with the nutrition transition and obesity epidemic can be grouped into four cross-cutting themes, which include: (i) the health/biological environment; (ii) the economic/food environment; (iii) the physical/built environment; and (iv) the socio/cultural environment. The solutions for the DBM problems are reasonably well recognized in each of its parts: under nutrition and over nutrition. However, the solutions have not been combined into an overarching policy and program framework, which together with raising awareness about the serious future implications for the low-and middle income countries is the aim of this paper.
Sistema de recomendación multimedia basado en perfiles de usuarios

La presente memoria detalla, de manera precisa, la implementacion de una aplicacion web para ordenador, especializada en la recomendacion cinematografica. La recomendacion sigue un algoritmo, el fundamento del cual reside en la Entropia de Shannon, consistente en compar ar la entropia de cada genero, calculada teniendo en cuenta las peliculas a las cuales el usuario ha otorgado una puntuacion, con la entropia del correspondiente genero, calculada mediante el mismo proceso explicado anteriormente pero anadiendo una posible pelicula a recomendar. El caso de estudio es el mundo cinematografico debido a que la informacion de referencia de la base de datos ha sido proporcionada, en su gran mayoria, por MovieLens.
Vancomycin-Induced Nephrotoxicity in Adolescents Receiving Extended Infusion: Case Series

Abstract Because of concerns of red man syndrome, our institution increased standard vancomycin infusion duration to 90 minutes for 1000-mg doses and 120 minutes for 2000-mg doses. However, in children and adolescents, the dosing interval remained every 6 to 8 hours. The purpose of this pilot study was to identify the incidence of supratherapeutic vancomycin serum concentrations (VSCs) and nephrotoxicity with extended-infusion vancomycin (≥90 minutes). Of the 7 adolescents who received extended-infusion vancomycin, 1 (14.2%) experienced supratherapeutic VSC and nephrotoxicity. Extended-infusion vancomycin for red man syndrome should include assessment of the dosing interval and frequent VSC monitoring if a 6-hour interval is indicated.
Segmentação de Imagens de Ultra-sonografia Intracoronária

This paper presents two methods to perform an automatic identification of the three major structures of the coronary artery - lumen, internal and external laminae - in images obtained by intracoronary ultrasound: Region Growing and Active Contours or Snakes, with special relevance to the later.
Resection-Intersection Bundle Adjustment Revisited

Bundle adjustment is one of the essential components of the computer vision toolbox. This paper revisits the resection-intersection approach, which has previously been shown to have inferior convergence properties. Modifications are proposed that greatly improve the performance of this method, resulting in a fast and accurate approach. Firstly, a linear triangulation step is added to the intersection stage, yielding higher accuracy and improved convergence rate. Secondly, the effect of parameter updates is tracked in order to reduce wasteful computation; only variables coupled to significantly changing variables are updated. This leads to significant improvements in computation time, at the cost of a small, controllable increase in error. Loop closures are handled effectively without the need for additional network modelling. The proposed approach is shown experimentally to yield comparable accuracy to a full sparse bundle adjustment (20% error increase) while computation time scales much better with the number of variables. Experiments on a progressive reconstruction system show the proposed method to be more efficient by a factor of 65 to 177, and 4.5 times more accurate (increasing over time) than a localised sparse bundle adjustment approach.
Microstrip antenna design with improved fabrication tolerance for remote vital signs monitoring and WLAN/WPAN applications at mm-wave and THz frequencies

A novel approach is introduced to design microstrip patch antennas (MPAs) with improved fabrication tolerance for highly demanded Millimetre-wave (mm-wave) (30-300GHz) and Terahertz (THz) (0.3-3THz) frequency applications. The presented MP A designing method overcomes the challenges which exist with the fabrication and implementation of the conventional MP A designs at mm-wave and THz frequencies. The following research contributions have been added to the state-ofthe- art work: (i) designing of improved size MPAs at 60GHz, 1 OOGHz, 635GHz and 835GHz to prove the designing concept, (ii) detail measurements and analysis of Remote Vital Signs Monitoring (RVSM) with various sizes of the proposed MPA arrays at 60GHz for high detection accuracy and sensitivity, (iii) designing and tes~ing of MP As for 60GHz wireless local and personal area networks (WLAN/WP AN) in point-to-pint, point-to-multipoint and dual-band applications, (iv) implementation and testing of particular Partially Reflective Surface, Dielectric Lens and Defected Ground Structures on the proposed MP A designs with novel configurations at 60GHz for bandwidth and gain enhancement, and (v~ a comprehensive experimental study on the performance of large array designs with the proposed MP A elements for mm-wave applications. The mentioned research work is explained in the coming chapters in details. Moreover, all mentioned work has already been published.
Wireshark & Ethereal Network Protocol Analyzer Toolkit

Ethereal is the #2 most popular open source security tool used by system administrators and security professionals. This all new book builds on the success of Syngress' best-selling book Ethereal Packet Sniffing.This book provides complete information and step-by-step Instructions for analyzing protocols and network traffic on Windows, Unix or Mac OS X networks. First, readers will learn about the types of sniffers available today and see the benefits of using Ethereal. Readers will then learn to install Ethereal in multiple environments including Windows, Unix and Mac OS X as well as building Ethereal from source and will also be guided through Ethereal's graphical user interface. The following sections will teach readers to use command-line options of Ethereal as well as using Tethereal to capture live packets from the wire or to read saved capture files. This section also details how to import and export files between Ethereal and WinDump, Snort, Snoop, Microsoft Network Monitor, and EtherPeek. The book then teaches the reader to master advanced tasks such as creating sub-trees, displaying bitfields in a graphical view, tracking requests and reply packet pairs as well as exclusive coverage of MATE, Ethereal's brand new configurable upper level analysis engine. The final section to the book teaches readers to enable Ethereal to read new Data sources, program their own protocol dissectors, and to create and customize Ethereal reports. Ethereal is the #2 most popular open source security tool, according to a recent study conducted by insecure.orgSyngress' first Ethereal book has consistently been one of the best selling security books for the past 2 yearsThe companion Web site for the book provides readers with dozens of open source security tools and working scripts
Associations between Relationship Maintenance Behaviors and Marital Stability in Remarriages

ABSTRACT Nearly half of adults in the U.S. indicated they had a close step-relative that included stepparents, stepchildren, and other close relationships. The prevalence of stepfamilies is rapidly increasing and represents a population that remains largely understudied. This study explored the roles of socioemotional behaviors (positivity, negativity, and sexual interest) on marital stability for different remarriage constellations (depending on which of the couple, both partners, or neither had previous children). This study uses dyadic relationship data from 879 couples. It was hypothesized that positivity and sexual interest would be inversely related to marital instability, while negativity will be correlated with marital instability.
DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients

ABSTRACT Aberrant expression of immune checkpoints (ICs) in cancer creates an immunosuppressive microenvironment, which supports immune evasion of tumor cells. We have recently reported that epigenetic modifications are critical for ICs expression in the tumor microenvironment (TME) of primary breast cancer (PBC) and colorectal cancer (CRC). Herein, we investigated transcriptomic expression of ICs (PD-1, CTLA-4, LAG-3, TIM-3, TIGIT) and PD-L1 in peripheral blood of PBC and CRC patients, compared to healthy donors (HD). We found that expressions of TIM-3, TIGIT, PD-L1 were significantly upregulated, while LAG-3 expression was downregulated in peripheral blood of PBC and CRC patients. Demethylation enzymes TET2 and TET3 were also upregulated. In addition, promoter DNA methylation status of PD-1 was significantly hypermethylated, while PD-L1 was hypomethylated in PBC and CRC patients. Furthermore, TIGIT was significantly hypomethylated only in CRC patients. Remarkably, promoter methylation status of LAG-3, TIGIT and PD-L1 was in concordance with transcriptomic expression in CRC: the more the hypomethylation, the higher the expression. In comparison, we found that CTLA-4, TIM-3, TIGIT and PD-L1 in PBC, and CTLA-4 in CRC patients were significantly upregulated in peripheral blood, compared with tumor tissues of the same patients. However, demethylation status of all ICs was higher in TT, except for TIGIT in PBC, and CTLA-4 in CRC patients. These data indicate that the underlying mechanisms behind peripheral upregulation of PD-L1 and TIGIT in cancer patients could be due to aberrant promoter methylation profile. Moreover, demethylation inhibitors together with anti-PD-L1/anti-TIGIT could be a more efficient therapeutic strategy in cancer patients.
Frictional Compliant Haptic Contact and Deformation of Soft Objects

This paper is concerned with compliant haptic contact and deformation of soft objects. A human soft fingertip model is considered to act as the haptic interface and is brought into contact with and deforms a discrete surface. A nonlinear constitutive law is developed in predicting normal forces and, for the haptic display of surface texture, motions along the surface are also resisted at various rates by accounting for dynamic Lund-Grenoble (LuGre) frictional forces. For the soft fingertip to apply forces over an area larger than a point, normal and frictional forces are distributed around the soft fingertip contact location on the deforming surface. The distribution is realized based on a kernel smoothing function and by a nonlinear spring-damper net around the contact point. Experiments conducted demonstrate the accuracy and effectiveness of our approach in real-time haptic rendering of a kidney surface. The resistive (interaction) forces are applied at the user fingertip bone edge. A 3-DoF parallel robotic manipulator equipped with a constraint based controller is used for the implementation. By rendering forces both in lateral and normal directions, the designed haptic interface system allows the user to realistically feel both the geometrical and mechanical (nonlinear) properties of the deforming kidney.
Flexible time-varying filter banks

Linear phase maximally flat FIR Butterworth filter approximations are discussed and a new filter design method is introduced. This variable cutoff filter design method uses the cosine modulated versions of a prototype filter. The design procedure is simple and different variants of this procedure can be used to obtain close to optimum linear phase filters. Using this method, flexible time-varying filter banks with good reconstruction error are introduced. These types of oversampled filter banks have small magnitude error which can be easily controlled by the appropriate choice of modulation frequency. This error can be further decreased by magnitude equalization without increasing the computational complexity considerably. Two dimensional design examples are also given.