Miracle-dz/UniFAR-FTUs huggingface dataset:
Evidencias sobre la vulnerabilidad institucional y su implicación en el incremento del riesgo de inundación en el litoral mediterráneo español

RESUMEN: La ordenación del territorio constituye el primer sistema defensivo no estructural ante las inundaciones, riesgo de origen natural con mayor incidencia en el litoral mediterráneo español. A pesar de las diversas referencias normativas y herramientas cartográficas relacionadas con los riesgos de inundación, el descontrolado y codicioso proceso de ocupación del recurso suelo han desplazado su consideración durante el proceso planificador. El presente trabajo se centra en evaluar la pasividad negligente adquirida por las corporaciones locales y autonómicas en sus ámbitos de gestión ante los riesgos de inundación al no considerar los criterios e instrumentos legalmente establecidos, en definitiva, determinar el nivel de riesgo establecido por las distintas administraciones al acrecentar la vulnerabilidad. Para su estimación se han cotejado a través de un SIG los preceptos establecidos en los distintos instrumentos de ordenación territorial local junto con la cartografía de áreas inundables (SNCZI). Como resultado se obtiene, por un lado, la ineludible exposición física ante los riesgos de inundación derivada de las características geográficas y climáticas del territorio y, por otro, el grado de incidencia de la componente humana como catalizador de la severidad de los fenómenos de inundación al no adoptar las medidas de ordenación territorial adecuadas.
A Preliminary Study on ZebraFish Thrombocyte Aggregation Induced by Adenosine Diphosphate

Adenosine diphosphate(ADP) infusion can effectively cause platelet to aggregate.We aimed at determining the effects of ADP on zebrafish viability,thrombocyte aggregates and Von Willebrand Factor(vWF) expression.Experiments show that the inhibition of ADP to the viability of 5 days post fertilization(5 dpf) zebrafish is concentration-dependent and time-dependent.We discover that ADP can induce zebrafish thrombocyte to aggregate by employing transgenic zebrafish with fluorescent markers to highlight the location of thrombocyte.Reverse Transcript PCR results show that vWF expression is up regulated in ADP-inducing thrombocyte aggregation.ADP therefore is a powerful tool for studying the zebrafish thrombocyte aggregation mechanism.
Metabolic engineering approaches for glutamate production in Corynebacterium glutamicum

Chapter 2 is the pre-peer reviewed version of the following article: Applied Microbiology and Biotechnology , Volume86, Issue3, 911-920, April 2010, which has been published in final form at http://dx.doi. org/10.1007/s00253-009-2360-6
The Abundance of O18 in Atmospheric Water and Water Vapour

Investigations into the O 18 -abundance in the precipitation from a warm front reveal a distinct process of fractionation explainable by the unequal pressures of the saturated vapours of H 2 O 16 and H 2 O 18 . An explanation is given of the low O 18 -abundance in glacial waters. A method of experimental investigation into the mechanism of the process of precipitation is discussed. DOI: 10.1111/j.2153-3490.1953. tb01076.x
The Functions of Arabinogalactan-Proteins in Angiosperms

Arabinogalactan-proteins(AGPs) are oxyproline/hydroxyproline-rich(Hyp-rich) proteins which are highly glycosylated,present at the cell wall,plasma membrane and extracellular matrix(ECM) throughout the plant kingdom.AGPs are considered to be an important family of glycosidoproteins,implicated in diverse vegetative and reproductive processes,including somatic embryogenesis,cell expansion,programmed cell death,wound responses,root morphology,pollen tube growth,and plant hormonal signaling pathways.With the rapid development of plant structural genomics and functional genomics,we have known expression patterns and functions of AGPs at closer range.This paper first summarizes the molecular structure and classification of AGPs,then focuses on its functional research on vegetative growth,reproductive development,programmed cell death,and molecular interaction as well as signal transduction,using genomic sequence information analysis,forward and/or reverse genetic approach.
Cloning and Analysis of a cDNA Encoding Key Enzyme Gene (hmgr) of the MVA Pathway in Medicinal Plant Euphorbia pekinensis

Based on the design of degenerated oligonucleotides according to the conservative regions of eight 3-hydroxy-3-methylglutaryl-CoA reductases from six plants and total RNA extracted from Euphorbia pekinensis,a 458 bp fragment of hmgr was obtained using reverse transcription PCR strategy.Through sequence analysis by BlastP online,the resulting protein showed high homology to 3-hydroxy-3-methylgluta-ryl-CoA reductase,with 90% identification compared with Eucommia ulmoides(AAV54051),86% with Andrographis paniculata(AAP14352),86% with Picrorhiza kurrooa(ABC74565),92% with Hevea brasiliensis(AAU08214),87% with Gossypium barbadense(ABC71314)and 88% with Gentiana lutea(BAE92730). Deduced amino acid sequence were also analyzed by PROSITE,ClustalX and Phylogenic tree,and data present evidence for the existence of 3-hydroxy-3-methylglutaryl-CoA reductase in E.peki-nensis,which is the first report of the hmgr gene isolated from E.pekinensis.
Growth Response and Physiological Change of Leymus chinensis Seedling Transplanted in Soil of Various pH

To investigate the survival rate and growth responses and physiological change of Leymus chinensis transplanted in soil of various pH,experiments of potted plant were conducted with the soils which have various pH by artificially mixed non-sodic soil with sodic soil,and the adaptation mechanisms of Leymus chinensis seedling in soil of various pH was elementary discussed.The results showed that the survival rate of seedling transplanted at ages of 2 leaves was 0% in the soil of pH 10.48,and the survival rate was 70% to 85% in soil which pH was 7.15 to 10.17. The length,tillering numbers,shoot dry weight and soluble sugar content of seedling transplanted were maximal when soil pH was 8.5(pH 7.87 to 8.72),but there was no significant differences with control.There was a significant positive correlations between soluble sugar content and tillering number and shoot dry weight.The change scope of the concentration of K+ in L.chinensis shoot was 13.4 to 21.0mg/g,Na+ was 1.5 to 12.4 mg/g and the ratio of K+ and Na+ was 1.1 to 13.7. The concentration of K+ was obviously decreased in the shoots of seedling with increasing of soil pH,which had a significant negative correlations with the concentration of Na+(r=-0.8045). Higher concentration of K+ in the shoot was one of the probable physiological mechanism for L.chinensis saline-alkali tolerance.
Molecular Homozygosity of Soybean Varieties (Lines) in Regional Test of China by Using SSR Markers

Genomic homozygosity of seeds is very important for protection of breeder’s right and sustainable production of agriculture. Highly informative microsatellite (SSR) markers, widely used in soybean genetic mapping and genetic diversity research, are useful for soybean genomic analysis. Thirty pairs of SSR primers were used to test the DNA of 1 068 soybean varieties (lines) from regional trials of China. The average SSR locus homozygosity for each year ranged from 94.9% to 97.6% each year. Among the 1 068 varieties (lines) in China regional test identified in five years, the soybean varieties (lines) with homozygosity higher than 85% and 90% accounted for 95.0% and 91.4%, respectively. Only 42 (3.93%) of the varieties (lines) had homozygosity less than 85%, which were mostly from North spring and Huanghuai summer soybean planting areas. Among the 42 varieties (lines) with homozygosity less than 85% only 11 had the yield 5% more than the controls, 20 had a yield reduction of 0.04% to 13.08%. Compared with those with 100% homozygosity, varieties with lower SSR loci homozygosity also had lower yield in regional trials. It is suggested that criterion of soybean homozygosity in the national regional test should not be less than 90% so as to insure the protection and sustainable utilization of new soybean varieties (lines) in production.
Efecto antioxidante del extracto hidroalcohólico de tilia platyphyllos scopoli “tilo de hoja ancha” en isquemia-reperfusión cerebral experimental en ratas

Los accidentes cerebrovasculares con sus complicaciones neurologicas son una de las principales causas de morbilidad y mortalidad en el mundo. En la actualidad se busca alternativas para tratar o disminuir el dano haciendo uso de propiedades de plantas medicinales. El presente trabajo evaluo el efecto antioxidante del extracto hidroalcoholico de Tilia platyphyllos Scopoli “tilo de hoja ancha” en isquemia-reperfusion (I/R) cerebral experimental en ratas. Materiales y metodos: Se evaluo el efecto neuroprotector de DE50 (300 mg/kg) y DE100 (600 mg/kg) de la planta frente a la lesion producida por la I/R en el cerebro de ratas, mediante la evaluacion de radicales libres y ceruloplasmina,. Las dosis de DE50 y DE100 mostraron su capacidad antioxidante contra la I/R. El mayor efecto neuroprotector ocurrio en la dosis mas alta. Sugerimos que la planta T. platyphyllos Scopoli posee efecto antioxidante contra la lesion hipoxica tisular inducida producida por la I/R en ratas.
Method to Evaluate the Sagittal Plane Mobility of the Medial Arch of the Shod Foot with Foot Orthosis

262 ABSTRACT Introduction:Midfootmobility plays an important role in the orthotic treatment of foot pathomechanical disorders, such as flexible pes planus and abnormal foot pronation. The sagittal plane mobility of the medial arch of only the unshod foot with a foot orthosis has been evaluated for improving therapeutic outcomes. Because foot orthoses are in-shoe devices, it is necessary to evaluate the sagittal plane mobility of the medial arch of the shod foot with a foot orthosis to optimize in-shoe orthotic effectiveness. Materials and Methods: This technical note describes a procedure using digital photography to evaluate the sagittal plane mobility of themedial arch of the shod foot with a foot orthosis. The procedure involves digitally photographing two weight-bearing states of the shoe in which the foot orthosis supports the foot: 1) 10% of body weight achieved by sitting, and 2) 50% of body weight achieved by standing. The two digital images of the shoe are then geometrically analyzed to calculate the displacement of the medial height of the dorsal surface of the shoe in response to the change in the two weight-bearing states. Conclusions: Clinicians and researchers can use the method described in this note to evaluate the sagittal plane mobility of the medial arch of the shod foot with a foot orthosis. The method is clinically useful for optimizing the in-shoe effectiveness of foot orthoses to treat foot pathomechanical disorders. (J Prosthet Orthot. 2019;31:262–266)
Progresses on the Effects of Microbial Metabolites on Plants

With the increasing researches on microbiology,combining plant physiology and plant pathology etc.,many activated metabolites produced by microorganisms have been known.These secretions can promote or inhibit some plants.The sorts of microbial metabolites,promotion and inhibition are generalized respectively.These two effects have great significance for agricultural production and biocontrol of plant diseases.
Full length cDNA cloning and tissue expression of major histocompatibility complex (MHC) class I from blunt snout bream (Megalobrama amblycephala)

RACE(Rapid Amplification of cDNA Ends) technique was used to clone "Pujiang No.1" blunt snout bream(Megalobrama amblycephala) MHC class Ⅰgene(Meam-MHC Ⅰ),and total three full-length cDNA sequences in the F0 and F8 generations were obtained by cloning and sequencing method,respectively.The sequences were 2 040-2 079 bp in length,including an 87-102 bp 5′-UTR,a 1 035-1 044 bp coding region,containing signal region,three(α1,α2,α3) domains,a transmembrane and cytoplasmic region(TM/CY),and 911-946 bp 3′-UTR.The coding region had 344-347 amino acids.Within F8 generation,the nucleotide/amino acid sequences similarities were as high as 89.0%/93.0%. But the values were relatively as low as 75%-77% /71% between generations,indicating obviously sequence polymorphism.The Meam-MHC I exhibited a classical 3D molecular structure,and compared to the PBR region of HLA-A2,the major differences were mainly in the five regions(I-V). It was revealed in the neighbor-joining tree that the blunt snout bream had the closest relationship with grass carp,far from salmon and trout,and still farther from,chicken and human.Semi-quantitative RT-PCR analysis demonstrated that Meam-MHC I transcript was detected at high level in gill,head kidney and blood,moderate in liver and spleen,and low in trunk kidney,gut and muscle.
Cloning and SNP Analysis of 1-Deoxy-D-xylulose-5-phosphate Reductoisomerases(DXR) in Litsea cubeba

Based on the results of transcriptome sequencing,the DXR gene c DNA was isolated from the flower bud of Litsea cubeba by the method of RT-PCR. At the same time,full-length sequence of DXR was first obtained from the genomic DNA by PCR and splice,and named as Lc DXR. Sequence analysis showed that the full-length c DNA of Lc DXR was 1 501 bp,including 5'non-coding region 34 bp and 3'non-coding region 53 bp and encoded 470 amino acids. The theoretical molecular weight of Lc DXR was 51. 12 kd and the isoelectric point was predicted as 6. 62. The full-length gene was 12 601 bp with 12 exons and 11 introns. Single nucleotide polymorphic( SNP) sites of Lc DXR from 10 sources were analyzed,the results showed that there were 10 SNPs within c DNA region,and 4 SNPs lead to amino acids changes. Point mutation was analyzed by Swiss-PDB Viewer to find fine structure changes resulted by amino acids mutations. The Lys119 Thr mutation in Anyuan,Jiangxi Province was shown to have H-bonds change,which may have an impact on the enzyme activity.
VARIETY AND DISTRIBUTION OF INTESTINAL FLORA OF APRIONA GERMARI (HOPE) LARVAE

The variety and distribution of the bacteria in the intestine of Apriona germari (Hope) were qualitatively and quantitatively studied from May 1999 to October 2000. A total of 21 different troops of bacteria belonging to 13 genera were isolated and identified from the intestinal fluid of 47 A. germari larvae The count and isolation rate of Staphyloccus cover 7.63±0.21 per gram gut and 100%, respectively, and it was the predominant and indigenous flora. The others were supposed to be transient floras. Different gut sections showed different flora compositions. Treptococcus, Enterobacter, Shigella and Bacillus were detected in all the four sections but their isolation rate was low. The normal intestinal floras in the fore-midmut, mid-midgut and hindgut of A. germari larvae were examined. The grand mean count of viable cells of the four sections was 7.35±0.30, 7.22±0.31, 6.89±0.36 and 7.84±0.28, respectively. The count of bacteria in the hindgut was greater than that in the mid-midgut and hind-midgut ( P 0.05). The abundance of genera detected in the sections was different, appearing in the order of hind-midgutmid-midgutfore-midguthinggut.
Evolutionary ecology of seaweed strength and flexibility

An organism’s success is largely dependent upon its ability to function and survive within the physical constraints of its environment. The wave-swept shoreline is one of the most mechanically challenging environments on Earth, with passing waves imposing hydrodynamic forces comparable to those in a hurricane every 5-10 seconds. Nonetheless, the wave-swept intertidal hosts an exquisite diversity of plants and animals. I used field and laboratory techniques to examine morphological and material adaptations of seaweeds to life in high-energy environments. In Chapter 2, I experimentally manipulated size and shape of 16 species of foliose red algae and showed that variation in tissue material and structural properties explain differences in hydrodynamic performance among speciesthinner, more flexible tissues allow blades to reconfigure in flow and reduce drag. Because material and structural properties may shift through an organism’s lifespan, I then investigated how reproduction and aging impact seaweed mechanical traits. In Chapter 3, I documented the mechanical costs associated with reproduction in the winged kelp, Alaria marginata, and found that shifts in other structural and material traits compensated for the increased drag associated with reproductive blades. In Chapter 4, a survey of 27 species of foliose algae showed that aging affected material properties of all species similarly.
The Elements of Identification with an Occupation

ONE of the major problems to which social psychologists are now addressing themselves is the process of identification and the nature and functioning of identity in conduct. These concepts are of strategic importance in any theory which attempts to relate the self and its workings to an ongoing social structure. As Foote 1 and Strauss 2 have pointed out, individuals identify themselves-answer the question "Who am I? " -in terms of the names and categories current in the groups in which they participate. By applying these labels to themselves they learn who they are and how they ought to behave, acquire a self and a set of perspectives in terms of which their conduct is shaped. It appears theoretically useful to break the concept of identification down into its components, both for comparative purposes and in order to provide finer tools for the analysis of specific problems of social structure and personal development. This paper is an attempt to provide such a breakdown for one type of identification, that of a man with his work. Its purpose is to discover, by comparing three groups of persons about to enter the work world, some of the threads from which the fabric of occupational identification is woven. The data on which this paper is based were gathered in the course of a study of the genesis of identification with an occupation in students doing graduate work in physiology, philosophy, and mechanical engineering. Graduate students were chosen for study not only because they were convenient but, more importantly, because of the central character of graduate school in developing professional identifications. Interviews lasting from one-half to two hours were tape recorded with students ranging from first year in graduate school to those about to receive the Ph.D.3 While identifications are not so clearly defined in the first year as they become later, the consistency of our findings indicates that the process is already well started at that time. The interviews were conducted informally. Qu stions were asked only to clarify points or to introduce some area in which information was desired that the interviewee had not spontaneously discussed in answer to the initial question: "How did you happen to get into. " Comparison of the three groups suggested four major elements of work identification: (1) occupational title, and associated ideology; (2) commitment to task; (3) commitment to particular organizations or institutional positions; and (4) significance for one's position in the larger society. In what follows we present brief discussions of each of these variables and comparisons of the physiologists, philosophers, and mechanical engineers 4 to illustrate their dimensions and
Valorisation de la macroalgue proliférante Grateloupia turuturu dans l'élevage de l'ormeau européen Haliotis tuberculata

L'ormeau Haliotis tuberculata, dont l'aquaculture est peu developpee en Europe, apparait comme un candidat potentiel pour la diversification des activites conchylicoles. Cependant, sa production rencontre deux principales limites. Tout d'abord, l'approvisionnement des elevages en nourriture de qualite constituent une depense majeure des entreprises. De plus, ces dernieres annees, les populations naturelles tout comme les elevages ont subi de fortes mortalites liees a la bacterie pathogene Vibrio harveyi. Par son caractere proliferatif, l'algue rouge Grateloupia turuturu, presente sur la cote atlantique, constitue une biomasse disponible qui pourrait etre valorisee pour l'aquaculture de l'ormeau. En effet, Grateloupia turuturu dispose d. Une composition biochimique interessante pour la croissance de l'ormeau qui montre une nette preference pour les algues rouges. Des tests d'alimentation on ete realises en elevage. Il apparait que cette algue n'est pas utilisable a l'etat frais comme aliment principal mais pourrait constituer un complement alimentaire. De plus, il a ete recemment mis en evidence que cette espece presente une activite antibacterienne. Cette activite a ete confirmee in vivo et in vitro sur la souche pathogene ORM4 de Vibrio harveyi
Curcumin Analogues Enhance Sensitivity of Resistant MCF-7 Cells to Doxorubicin

Cancer is a complex disease due to the complexity of molecular mechanism. Therefore, the strategy in cancer therapy should be targeted on the proteins involved in signaling processes lead to the growth and development of cancer cells and also to the proteins involved in resistant mechanisms of cancer (Hanahan and Weinberg, 2011). Inhibition of Epidermal Growth Factor Receptor (EGFR), HER2 and Estrogen Receptor (ER) in breast cancer cells, has been shown to inhibit the growth and development of breast cancer cells (Vora et al., 2009). Overexpression of HER2 in the biliary epithelium of transgenic mice and in colorectal cancer cells led to an increase of COX-2 expression (Vadlamudi, 1999; Kiguchi et al., 2001). Doxorubicin (Dox) is a chemotherapeutic agent used to treat breast cancer. However, the use of Dox causes resistance of the cancer cells. Dox induces the expression of P-glycoprotein (Pgp) (Byun et al., 2005) that possibly correlated to the NF-κB activation (Shishodia et al., 2003). Therefore, decreasing the expression and inhibiting of HER2, EGFR, ER, GST, COX-2, NF-κB and Pgp should
Protein and pathway engineering in biocatalysis

Isolated enzyme or whole cell biocatalysts can be used to carry out biotransformations in which challenging chemical conversions such as carbon-carbon bond formations, oxidations, aminations or hydrolyses are achieved with very high atom efficiency and enantioselectivity. Whole cells can also be used to carry out the bioconversion of biomass materials into high-value chemicals and medicines. Recent protein engineering advances are described which will enable enzymes to be more efficiently improved for use in large-scale biotransformations. A new era of pathway engineering is also discussed, which combines metabolic and protein engineering to synthesise desired molecules by microbial cells. Novel pathways have been created by transplanting pathways from other organisms, and also by engineering de novo pathways that synthesise new chemicals.
Tensile stress in jets of viscoelastic fluids. I

A viscoelastic fluid jet is treated as a moving infinite string under slowly varying tension. When the system is subjected to a sinusoidal point vibration, the resulting wave form enables the tension to be determined along the jet. The total tension is composed of a surface reaction and an internal, decaying tension. The surface reaction may be calculated from the surface tension of the jet fluid and the radius of the jet. Data for 1.4 and 1.7% carboxymethylcellulose water solutions are presented for three different jet radii and for solution temperatures of 5, 25, and 35°C. It is found that the observed tensions approach the calculated surface reaction far from the nozzle. The rate of decay is a function of concentration and temperature. The internal tension for a 1.7% solution at 25°C. was observed to decay from about 8000 to 500 dynes/cm.2 in 200 milliseconds. Relaxation times of 0.27 sec. for 1.4% and 0.32 sec. for 1.7% solutions at 25°C. describe the internal tensile properties between 40 and 200 milliseconds after ejection.