Miracle-dz/UniFAR-FTUs huggingface dataset:
Study on the Role of Alternaria alternata in the Etiology of Allergic Asthma in Patients Admitted to Loghman Hospital by using the Skin Prick Test and Solid-phase Immunoassay

The prevalence of respiratory allergies, especially those induced by fungi such as Alternaria alternata, has dramatically increased over the past decade. This increase has caused major health problems worldwide. This study aimed to investigate the role of A. alternata in the etiology of allergic asthma, by using the skin prick test and assessment of IgE specific to the fungus in the patient's sera. Methods: This study enrolled 202 patients with allergic asthma, aged 12 to 83 years. Participants included 40.1% males and 59.9% females who were enrolled after recording demographic information. A skin prick test with the whole cell extract of A. alternata was performed on the epidermis of the patients' forearms. Histamine and normal saline were used as positive and negative controls, respectively. Serum levels of IgE specific for A. alternata were measured for all patients using the ImmunoCAP Phadiatop method in which the specific A. alternata allergen cocktail that connected to the solid phase reacted to IgE antibodies in each patient's sera. Data were analyzed by analysis of variance and chi-square tests. Results: Among 202 patients with allergic asthma, 14 (6.93%) had mild asthma, 73 (36.10%) were moderate asthmatics and 115 (56.90%) had severe asthma. In total, 14 (6.93%) patients were positive for both the skin test and IgE specific to A. alternata, 35 (17.33%) had negative specific IgE and positive skin test results, and 36 (17.82%) had a positive specific IgE and negative skin test. A total of 117 (57.92%) patients were negative for both tests. Conclusion: The results of this study showed the presence of IgE specific for A. alternata in 50 of 202 (24.75%) patients diagnosed with allergic asthma. The skin prick test was successfully used as a screening test. The results were further confirmed by solid-phase immunoassay of the IgE specific for A. alternata crude allergenic extract.
Construção de Códigos Espaço-temporais de Treliça via Partição de Reticulados

This paper proposes a systematic method for building Space-Time Trellis Codes in wireless communication system that employs MIMO when submitted in fading channels. The method is based on the theory of lattices that will combine concepts of rotated constellations and partition lattices. This methodology ensures the greatest possible diversity in the process of modulation used.
La microsporidiose intestinale : diagnostics réalisés au laboratoire de Parasitologie-Mycologie de 1994 à 2013 et étude des cas chez les transplantés rénaux du service de Néphrologie du CHU de Rouen.

La microsporidiose intestinale humaine fut identifiee lors de la pandemie de SIDA dans les annees 1980. Cette pathologie est une infection opportuniste qui se developpe chez les personnes immunodeprimees en particulier les patients atteints de SIDA et les patients transplantes. Les deux especes principales pathogenes chez l’Homme en cause sont Enterocytozoon bieneusi et Encephalitozoon intestinalis. Cette pathologie se transmet par voie oro-fecale, avec pour principal signe clinique la diarrhee. Cette infection est spontanement resolutive chez l’immunocompetent mais des formes graves et parfois meme disseminees peuvent se rencontrer en cas d’immunodepression severe. Les traitements actuellement disponibles sont l’albendazole, le traitement de choix pour les microsporidioses intestinales, oculaires et disseminees dues au genre Encephalitozoon, la fumagilline, qui a de nombreux effets indesirables graves et frequents, utilisee pour traiter Enterocytozoon bieneusi et le nitazoxanide, qui beneficie d’une autorisation temporaire d’utilisation nominative en France, qui permet egalement de traiter Enterocytozoon bieneusi et serait efficace in vitro sur Encephalitozoon intestinalis. Ce travail se divise en deux parties, en premier lieu est fait un rappel sur l’agent causal, son cycle de developpement, ses consequences pathologiques, le diagnostic et le traitement de la microsporidiose intestinale. La seconde partie detaille la pratique du diagnostic biologique et les patients en ayant beneficie au CHU de Rouen et dans cette partie, nous decrivons plus particulierement cinq observations de microsporidiose chez des patients transplantes renaux pris en charge dans le service de Nephrologie du CHU de Rouen.
STRATEGIES FOR PROMOTING HEALTH AND REDUCING MEDICAL EXPENSES IN JAPAN USING PURPOSE IN LIFE/IKIGAI, MODERATE EXERCISE, AND A WELL-BALANCED DIET

[Purpose] This study attempted to clarify correlations of age, life expectancy, and anxiety to disease, mortality, and medical expenses in consideration of the modern daily lifestyle in Japan. [Methods] Time series data for each variable were collected from Japanese public institutes, such as the Japanese government. One-sample t-tests, Wilcoxon tests, and Kendall correlation analyses were performed to clarify differences and correlations between each variable. [Results] Having external sources of happiness, including a “happy family circle” and “meeting and discussing ideas with friends and acquaintances” was found to be significantly more related to higher levels of happiness compared to internal sources of happiness, including “devotion to study and culture” and “devotion to hobby and sports” (p<0.001). Having internal sources was related to significantly more happiness than work (p<0.001). Satisfaction with the amount of materials, food, and rest were each significantly higher than dissatisfaction for each corresponding item (p<0.001). Regular exercise, steps per day, skipping breakfast, vegetable consumption, and legumes consumption were all poorer than the standards proposed by Japanese public institutes (p<0.001 in all tests). Lack of sleep tended to be greater than standard values proposed by Japanese public institutes (p=0.055). Age, life expectancy, and anxiety were positively correlated with number of patients, proportion of mortalities, and medical expenses. [Conclusion] We suggest that people should establish “purpose in life/Ikigai” related to internal sources of happiness, which are more stable than external sources, and then an effective way to cope with stress. This process should be combined with moderate aerobic exercise and eating a well-balanced diet. Doing so may contribute to decreasing anxiety and to a decreased national healthcare burden.
Research: Epidemiology Prevalence of diabetes in Malaysia and usefulness of HbA 1c as a diagnostic criterion

Aim The prevalence of diabetes mellitus among Malaysians aged 30 years of age has increased by more than twofold over a 20-year period. This study aimed to determine the current status and to evaluate the diagnostic usefulness of the HbA1c cut-off point of 48 mmol/mol (6.5%). Methods Using a two-stage stratified sampling design, participants aged 18 years were recruited from five zones selected to represent Malaysia. An oral glucose tolerance test was performed on all those not known to have diabetes. Results A total of 4341 subjects were recruited. By World Health Organization criteria, the prevalence of diabetes mellitus was 22.9%; of that percentage, 10.8% was known diabetes and 12.1% was newly diagnosed diabetes. Diabetes was most prevalent amongst Indians (37.9%) and Malays (23.8%). Prevalence of new diabetes mellitus was only 5.5% (95% CI 4.9–6.3) when based on the HbA1c diagnostic criteria of 48 mmol/mol (6.5%) and, although the cut-off point was highly specific (98.1%), it was less sensitive (36.7%) compared with 45 mmol/mol (6.3%), which showed the optimal sum of sensitivity (42.5%) and specificity (97.4%) in identifying new diabetes mellitus. Conclusion This study recorded an overall diabetes prevalence of 22.6%, almost a twofold increase from 11.6% reported in 2006. This was likely attributable to the higher prevalence of new diabetes (12.1%) diagnosed following an oral glucose tolerance test. An HbA1c of 45 mmol/mol (6.3%) was found to be a better predictive cut-off point for detecting new diabetes in our multi-ethnic population. Diabet. Med. 00, 000–000 (2013)
(1R,2R)-N,N′-Bis(ferrocenylmethyl)-1,2-diphenylethane-1,2-diamine

The title compound, [Fe2(C5H5)2(C26H26N2)], was synthesized from a chiral diamine and ferrocenecarboxaldehyde and subsequent reduction with NaBH4. It has two chiral centers which both exhibit an R configuration. Two ferrocene groups are present in the molecular structure, with their cyclopentadienyl ring planes showing an almost perpendicular arrangement [dihedral angle 88.6 (1)°].
Diabetes Microvascular and Macrovascular Disease in Africa

This review on the prevalence and characteristics of diabetes micro- and macrovascular disease in Africa is based on a bibliographical Medline search and diabetes conference proceedings of published data over the past decade. The prevalence of diabetic retinopathy varies from 16 to 77% depending on the duration of diabetes and glycaemic control, with severe retinopathy representing 15% of all cases. At diagnosis, 21–25% of type 2 patients and 9.5% of type 1 patients have retinopathy. The prevalence of nephropathy varies between 32–57% after a mean duration of diabetes of 5–10 years, and 5–28% within the first year following the diagnosis of diabetes. The prevalence of neuropathy varies widely depending on the methodology used. Macrovascular complications of diabetes are considered rare in Africa despite a high prevalence of hypertension. Coronary heart disease may affect 5–8% of type 2 diabetic patients and cardiomyopathy up to 50% of all patients. Lower extremity amputation varies from 1.5 to 7%, and about 12% of all hospitalized diabetic patients have foot ulceration. Neuropathy underlies diabetic foot more often than peripheral vascular disease. In conclusion, whereas microvascular complications of diabetes are highly prevalent and occur early during the course of disease, macrovascular disease is rare. Late diagnosis of diabetes, poor metabolic control and non-standardized diagnostic procedures rather than genetic predisposition may account for this difference from other populations around the world.
Blind Source Separation for Changing Source Number: A Neural Network Approach with a Variable Structure

Blind source separation (BSS) problems have recently become an active research area in both statistical signal processing and unsupervised neural learning. In most approaches, the number of source signals is typically assumed to be known a priori, but this does not usually hold in practical applications. Although the problem of determining the unknown source number has been studied recently, the BSS problem when the source number is changing dynamically is not yet considered. The main objective of this paper is to study and solve these two problems. Its basic idea is to utilize the correlation coe¢ cients between output components of the neural network (NN) as a mean for determining the unknown source number and/or detecting dynamical change of the source number, and is to develop a neural network with variable structure to perform the corresponding adaptive blind source separation.
Fragile X-Associated Tremor/Ataxia Syndrome: Autopsy Brain MR Imaging Alterations Correlated with Histopathology

Purpose To correlate MR imaging findings with brain histopathology in autopsy material obtained from subjects with fragile X-associated tremor/ataxia syndrome (FXTAS). FXTAS is a newly described late onset neurodegenerative disorder characterized by cerebellar ataxia, tremor, and dementia. It occurs in older individuals with premutation alleles for fragile X syndrome (55-200 CGG repeats). The clinical syndrome (1), MR imaging findings (2), and the results of histologic study of nonimaged brain autopsy material (3) have been described recently.
[2,7-Dihydroxy-8-(4-phenoxybenzoyl)naphthalen-1-yl](4-phenoxyphenyl)methanone

In the title compound, C36H24O6, the benzoyl groups at the 1- and 8-positions of the naphthalene system are in an anti orientation. Both carbonyl groups form intramolecular O—H⋯O hydrogen bonds with hydroxy groups affording six-membered rings. The benzene rings of the benzoyl groups make dihedral angles of 59.26 (13) and 59.09 (13)° with the naphthalene ring system. Zigzag C—H⋯O chains and ladder C—H⋯O chains between the phenoxybenzoyl groups along the ab diagonals form an undulating checkered sheet. The molecules are further connected into a three-dimensional network by C—H⋯π interactions.
THE FAMILY'S FEELINGS IN INTERACTION WITH THE NURSING TEAM

This qualitative cross-sectional field study, carried out between August and September 2011 with 30 family members who had been through the experience of being a companion in hospital, aimed to ascertain their feelings in the interaction with nursing, identifying points of interference, expectations and suggestions. The quantitative results from the interviews were analyzed with the help of descriptive statistics, while the qualitative results were analyzed through Bardin's content analysis, resulting in the categories Welcoming and efficient-efficacious Communication. The positive points were related to behavior and technical action: the negative, to administrative conditions and confusion about the role of the companion. The expectations were met, pointing to the positive, satisfactory perception of the quality of the care; the suggestions valued the operational and interactional aspects. It was concluded that the perception of the companion about the quality of care provided by the nursing team was good, with the relational aspects being cited most.
[μ-1,6-Bis(diphenylarsanyl)hexane]bis[chloridogold(I)]

In the title compound, [Au2Cl2(C30H32As2)], each Au atom is coordinated by As and Cl atoms in an approximately linear geometry. In the crystal, molecules are linked into two-dimensional networks parallel to the ac plane via intermolecular C—H⋯Cl interactions. One of the phenyl rings is disordered over two positions, with site occupancies of 0.518 (8) and 0.482 (8).
An investigation of attitudes of k--12 teachers toward computer technology use in schools in a rural mississippi district

This study investigates K-12 teachers' attitudes toward computer technology use in schools. The study looks at teacher variables that might affect the implementation of computer use in the learning environment. A sample of 179 teachers in a Northeast Mississippi school district participated in this study. The survey, the Computer Attitude Scale (CAS), consisted of two sections. In section one, teachers were asked to provide demographic information about themselves such as computer experience, access to a computer at home, age, gender, teaching level, teaching field, ethnicity, and education level. The second section was a 40-item questionnaire used to measure inservice teachers' attitudes toward computer technology. Analysis of variance (ANOVA) was used to analyze mean differences in attitudes based on computer experience, computer at home, teaching field, teaching level, and age. The result revealed that there were significant differences between teachers' attitudes as related to the teaching levels. No significant differences were found among computer anxiety, computer confidence, computer liking, and computer usefulness based on age, and teaching field. T-tests were used to analyze mean differences in attitudes based on gender and ethnicity. No significant differences were found among computer anxiety, computer confidence, computer liking, and computer usefulness based on ethnicity and gender. From these results, it was concluded that school districts could provide opportunities for inservice training and staff development for all teachers in educational technology with focus on computer use in the classroom and teachers attitude. It was also concluded that teachers should be trained in the ways that computer technology can be used in their work environment as well.
Immigrant Women Living with HIV: Communication with Healthcare Providers and the Role of Interpreters on Accessing Healthcare Services in Norway

Objective: This study aims to explore immigrant women living with HIV’s perception of their communication with healthcare providers, the use of interpreters and access to health information. Method: A qualitative study, gathering data through in-depth interviews and focus group discussion was used. The participants were immigrant women living with HIV in Norway and interpreters. Result: Communication between immigrant women living with HIV and healthcare providers is poor as a result of the language barrier present, limited consultation time with doctors, and fear of stigma. Communication is also negatively affected by the limited use of qualified interpreters and fear of using interpreters from the same country as the immigrant women. The result also shows that immigrant women living with HIV expect more health information from doctors, and want doctors to be the primary source of information about HIV. Conclusion: Healthcare providers need to offer health information based on individual needs and need to address the concerns of immigrant women living with HIV. In this regard information from treating doctors is most crucial. Immigrant women with HIV consider the usefulness of interpreters as very limited, mostly due to the fact that the interpreters provided by the health services compromise the patients need for confidentiality. This creates anxiety among immigrant HIV positive women, due to fear of exposing their HIV status to friends and other members their immigrant communities. The use of trained interpreters will to some extent improve communication between patients and healthcare providers, and will also reduce the breaches of patient confidentiality causing fear amongst HIV immigrant women.
The effect of resistance, endurance, and combination exercise on lipid metabolism and non-traditional cardiovascular disease risk markers in previously untrained men

The Effect of Resistance, Endurance, and Combination Exercise on Lipid Metabolism and Non-Traditional Cardiovascular Disease Risk Markers in Previously Untrained Men. (August 2008) Steven Edward Martin, B.S., Ohio State University; M.S., Texas A&M University Chair of Advisory Committee: Dr. Stephen F. Crouse While adhering to an active lifestyle has been associated with a more favorable lipid profile and reduced risk of coronary heart disease (CHD), information regarding the optimal training modality is not well defined. This project examined the acute and chronic effects of endurance (ET), resistance (RT), and combination endurance / resistance (CT) exercise on lipid metabolism and non-traditional CHD risk markers in untrained men. Thirty-one subjects were randomly assigned to participate for 12 weeks in one of three exercise groups: ET, RT, or CT. To measure the effects of acute exercise on lipid metabolism, fasting blood samples were obtained before (baseline) and 24 hours after (24 h) acute exercise (treadmill jogging at 70% V . O2peak, 350 kcals; weight lifting exercise at 70% of 1RM; combination of treadmill jogging and weight lifting at 70% maximal capacity, 350 kcals). Blood variables were adjusted for plasma volume shifts. This acute exercise protocol was completed on two different occasions corresponding to 0 and 12 weeks of training.
O R IGINAL AR T ICLE The steroid-responsive hiccup refl ex arc: Competitive binding to the corticosteroid-receptor?

Hiccups occurring secondary to high-doses of corticosteroids are a well-recognized problem in the fi eld of neurosurgery. Numerous reports of oral, intravenous and intraarticular corticosteroids inducing hiccups exist in the literature. To date, there is only one case of anabolic steroids inducing hiccups. We now present a case of a patient who underwent a suboccipital craniotomy for resection of a cerebellar pontine angle meningioma. Postoperatively the patient was on high doses of Decadron and Oxandrin, an anabolic-anticatabolic agent used to combat the deleterious effects of corticosteroids. The patient suffered intractable hiccups postoperative day one, resistant to Thorazine. Oxandrin was discontinued to assess the possibility of a anabolic steroid-induced singultus. The hiccups resolved within 24 hours. This report validates the previous report on anabolic steroids inducing hiccups and exemplifi es the ability for steroids as a class, due to there backbone structural homology, to induce function even as competitive inhibitors.
Necessity of Radiography in Young Adults presenting with Low Back Pain of Short Duration

Background and Objectives: The occurrence of low back pain of short duration and without positive clinical findings is high. 15% and 30% of the population suffer from this condition. Young working adults are most commonly affected by this condition. Aim of this study is to assess the necessity of plain radiography of lumbosacral spine in diagnosing and treating young patients presenting in Orthopaedic outpatient department with low back pain of short duration without history of trauma and no positive clinical findings. Methods: We prospectively studied 500 young patients of age between 25 to 40 years presenting with low back pain of less than 3 months duration without any history of trauma and no positive clinical finding. We excluded patients with history of trauma, fever, patients with radiating pain, neurodeficit, Patients with bladder/bowel complaints and Patients with any other systemic disorder. All these patients received standard treatment in the form of short term medication, postural training and application of ergonomic principles while working. Results: 64% of the patients recovered fully within 2 weeks of treatment. 36% of the patients were not relieved hence Lumbosacral spine radiographs were performed after 2 weeks of treatment. Positive findings on radiographs were early degenerative changes and loss of lumbar lordosis due to para-spinal muscle spasm, seen in 9.7%of the patients in whom radiographs were performed. These radiographic changes were not indicative of different modality of treatment, hence we continued the same treatment and further31% of the patients were recovered fully after 4 weeks of treatment. Interpretation and Conclusions: Performing lumbo-sacral radiographs does not have any influence on treatment or outcome in young patients presenting with low back pain of less than 3 months duration without any history of trauma and no positive clinical finding. Key words: Low back pain, Lumbosacral spine radiograph