Miracle-dz/UniFAR-FTUs huggingface dataset:
Intraoperative and postoperative risk factors for anastomotic leakage and pneumonia after esophagectomy for cancer.

Morbidity and mortality after esophagectomy are often related to anastomotic leakage or pneumonia. This study aimed to assess the relationship of intraoperative and postoperative vital parameters with anastomotic leakage and pneumonia after esophagectomy. Consecutive patients who underwent transthoracic esophagectomy with cervical anastomosis for esophageal cancer from January 2012 to December 2013 were analyzed. Univariable and multivariable logistic regression analyses were used to determine potential associations of hemodynamic and respiratory parameters with anastomotic leakage or pneumonia. From a total of 82 included patients, 19 (23%) developed anastomotic leakage and 31 (38%) experienced pneumonia. The single independent factor associated with an increased risk of anastomotic leakage in multivariable analysis included a lower minimum intraoperative pH (OR 0.85, 95% CI 0.77-0.94). An increased risk of pneumonia was associated with a lower mean arterial pressure (MAP) in the first 12 hours after surgery (OR 0.93, 95% CI 0.86-0.99) and a higher maximum intraoperative pH (OR 1.14, 95% CI 1.02-1.27). Interestingly, no differences were noted for the MAP and inotrope requirement between patients with and without anastomotic leakage. A lower minimum intraoperative pH (below 7.25) is associated with an increased risk of anastomotic leakage after esophagectomy, whereas a lower postoperative average MAP (below 83 mmHg) and a higher intraoperative pH (above 7.34) increase the risk of postoperative pneumonia. These parameters indicate the importance of setting strict perioperative goals to be protected intensively.
Roles and Teams Hedonic Games

We have introduced a new model of hedonic coalition formation game, which we call Roles and Teams Hedonic Games (RTHG). In this model, agents view coalitions as compositions of available roles. An agent's utility for a partition is based upon which role she fulfills within the coalition and which roles are being fulfilled within the coalition. The major contributions of the paper include designing the RTHG model, with its corresponding stability and (NP-hard) optimization criteria, designing a heuristic partitioning algorithm and local search algorithm, implementation and testing.
Cerebral Tissue Oxygenation and Regional Oxygen Saturation Can Be Used to Study Cerebral Autoregulation in Prematurely Born Infants

The coupling of cerebral intravascular oxygenation (dHbD) with mean arterial blood pressure (MABP) was taken as a reflection of autoregulation assuming constant arterial oxygen content. However, this method is sensitive to movement artifacts. We examined whether the cerebral tissue oxygenation index (cTOI) and regional oxygen saturation (rScO2) may replace dHbD and changes in total Hb (dHbT), respectively. Correlation (COR) and coherence (COH) were used to measure the agreement of MABP with rScO2/dHbT and cTOI/dHbD. dHbD/cTOI and dHbT/rScO2 recordings of, respectively, 34 and 20 preterm infants in need for intensive care were studied during the first days of life. dHbD and cTOI were obtained with the NIRO300 and rScO2 and dHbT with the INVOS4100. Invasive MABP was measured continuously. COR and COH scores of MABP versus dHbD/dHbT were compared with the corresponding ones by replacing dHbD/dHbT by cTOI/rScO2, respectively. Generally, no significant score differences were found for dHbD/cTOI. Differences for dHbT/rScO2 were slightly larger but still within the normal variation of the parameters. Differences become insignificant when restricting calculations to epochs of larger variation in MABP (>10 mm Hg). Hence, we suggest that cTOI and rScO2 can be used to study cerebral autoregulation in newborns.
The effect of non‐surgical weight loss interventions on urinary incontinence in overweight women: a systematic review and meta‐analysis

Although the aetiology of urinary incontinence can be multifactorial, in some cases weight loss could be considered as a part of the therapeutic approach for urinary incontinence in people who are overweight. The objective of this study was to review and meta‐analyse the effect of non‐surgical weight loss interventions on urinary incontinence in overweight women. Web of Science, PubMed, Pedro, SPORTDiscus and Cochrane were systematically searched for clinical trials that met the a priori set criteria. Data of women who participated in non‐surgical weight loss interventions (diet, exercise, medication or a combination) were included in the meta‐analysis. After removing duplicates, 62 articles remained for screening on title, abstract and full text. Six articles (totalling 2,352 subjects in the intervention groups) were included for meta‐analysis. The mean change in urinary incontinence (reported as frequency or quantity, depending on the study) after a non‐surgical weight loss intervention, expressed as standardized effect size and corrected for small sample sizes (Hedges' g), was −0.30 (95%CI = −0.47 to −0.12). This systematic review and meta‐analysis shows evidence that a non‐surgical weight loss intervention has the potential to improve urinary incontinence and should be considered part of standard practice in the management of urinary incontinence in overweight women.
PENGARUH RASIO KEUANGAN TERHADAP PROFITABILITAS PERBANKAN DI INDONESIA

In general, profitability or rent-ability is the capability of a company in generating profit during a certain period. The profitability of the company describes the comparison between profits and the assets or capital which generates its profit. The purpose of this research is to test the influence of Capital Adequacy Ratio (CAR), Loan to Deposit Ratio (LDR), and Non Performance Loan (NPL). The samples are 28 banking companies that have been selected by using purposive sampling from the research population i.e. the entire banking companies which are listed in Indonesia Stock Exchange (IDX) from 2010 to 2013. The classic assumption test and the multiple regressions analysis with the assistance of SPSS 20 version has been used as the statistics test instruments. The result of the result describes that overall the regressions model of this research has met the classic assumption test, which means that the regressions model of this research is free from any symptoms of multicolinearity, heteroscedasticity, autocorrelation and the generated data has been normally distributed. The multiple regressions analysis describes that Capital Adequacy Ratio (CAR) has significant and negative influence to the profitability, Loan to Deposit Ratio (LDR) has not significant and positive influence to the profitability, Non Performance Loan (NPL) has significant and negative influence to the profitability. Keywords: Capital Adequacy Ratio (CAR), Loan to Deposit Ratio (LDR), Non Performance Loan (NPL), and Profitability
Early MRI in the management of the clinical scaphoid fracture

Objectives The ‘clinical scaphoid fracture’ remains a common problem faced by emergency physicians. Early magnetic resonance imaging (MRI) has been used to routinely investigate such patients presenting to the emergency department of Aberdeen Royal Infirmary since 2002. The aim of this study was to evaluate the effectiveness of this strategy in the diagnosis of occult scaphoid fracture. Methods This was a retrospective cohort study of patients presenting with symptoms and signs suggestive of scaphoid injury and normal initial radiographs. Patients undergoing MRI evaluation of a suspected scaphoid injury between September 2002 and June 2008 were identified from records. The number of patients with scaphoid fractures and other significant pathology diagnosed on MRI was recorded. Results A total of 651 patients were included in the study. A scaphoid fracture was diagnosed in 11% of patients. Using the &khgr;2 test, there was evidence of an association between sex and type of injury (&khgr;2=58.0, P<0.001). Male patients were more likely to have scaphoid injuries; female patients were more likely to have no injury. There was also evidence of an association between age group and type of injury (&khgr;2=11.8, P=0.003). Those in the younger age group were more likely to have scaphoid injuries. Conclusion Early MRI can reliably detect radiologically occult scaphoid fractures and accurately delineate the anatomy of other injuries that may present with similar symptoms. This strategy avoids further radiation and can be incorporated as a part of an emergency department management pathway. Early and accurate diagnosis is in the patient's interest and allows timely intervention.
Cyclic space-frequency filtering for BICM-OFDM systems with multiple co-located or distributed transmit antennas

In this paper, we introduce cyclic space-frequency (CSF) filtering for orthogonal frequency division multiplexing (OFDM) systems using bit-interleaved coded modulation (BICM) and multiple transmit antennas for fading mitigation, and discuss the extension to orthogonal frequency division multiple access (OFDMA) systems. CSF filtering is a simple form of space-frequency coding (SFC) and may be viewed as a generalization of cyclic delay diversity (CDD) where the cyclic delays are replaced by CSF filters. CSF is applicable to both traditional multiple-input multiple-output systems with co-located transmit antennas and cooperative diversity systems with decode-and-forward relaying and distributed transmit antennas. Similar to CDD and in contrast to other SFC schemes, CSF filtering does not require any changes to the receiver compared to single-antenna transmission. Based on the asymptotic pairwise error probability of the overall system we derive an optimization criterion for the CSF filters for co-located and distributed transmit antennas, respectively. We show that the optimum CSF filters are independent of the interleaver if they do not exceed a certain length. If this length is exceeded, the adopted interleaver has to be carefully taken into account in the CSF filter design. For several special cases we derive closed-form solutions for the optimum CSF filters and for the general case we provide various CSF filter design methods. Our simulation results show that CSF filtering can achieve significant performance gains over existing CDD schemes.
Intracellular Gene Expression Profile of Listeria monocytogenes

ABSTRACT Listeria monocytogenes is a gram-positive, food-borne microorganism responsible for invasive infections with a high overall mortality. L. monocytogenes is among the very few microorganisms that can induce uptake into the host cell and subsequently enter the host cell cytosol by breaching the vacuolar membrane. We infected the murine macrophage cell line P388D1 with L. monocytogenes strain EGD-e and examined the gene expression profile of L. monocytogenes inside the vacuolar and cytosolic environments of the host cell by using whole-genome microarray and mutant analyses. We found that ∼17% of the total genome was mobilized to enable adaptation for intracellular growth. Intracellularly expressed genes showed responses typical of glucose limitation within bacteria, with a decrease in the amount of mRNA encoding enzymes in the central metabolism and a temporal induction of genes involved in alternative-carbon-source utilization pathways and their regulation. Adaptive intracellular gene expression involved genes that are associated with virulence, the general stress response, cell division, and changes in cell wall structure and included many genes with unknown functions. A total of 41 genes were species specific, being absent from the genome of the nonpathogenic Listeria innocua CLIP 11262 strain. We also detected 25 genes that were strain specific, i.e., absent from the genome of the previously sequenced L. monocytogenes F2365 serotype 4b strain, suggesting heterogeneity in the gene pool required for intracellular survival of L. monocytogenes in host cells. Overall, our study provides crucial insights into the strategy of intracellular survival and measures taken by L. monocytogenes to escape the host cell responses.
Insertion of a Suicide Gene into an Immortalized Human Hepatocyte Cell Line

For developing a bioartificial liver (BAL) device, an attractive alternative to the primary human hepatocytes would be the use of highly differentiated immortalized human hepatocytes with a safeguard. To test the feasibility, the primary human hepatocytes were immortalized by a plasmid SV3neo encoding simian virus 40 large T antigen (SV40Tag) gene. A highly differentiated hepatocyte line OUMS-29 was established. A suicide gene of herpes simplex virus-thymidine kinase (HSV-TK) was retrovirally introduced into OUMS-29 cells as a safeguard for clinical application. One of the resulting HSV-TK-positive cell lines, OUMS-29/ tk, grew in chemically defined serum-free medium with the gene expression of differentiated liver functions. OUMS-29/tk cells were 100 times more sensitive to ganciclovir compared with unmodified OUMS-29 cells in in vitro experiments. We have established a tightly regulated immortalized human hepatocyte cell line. Essentially unlimited availability of OUMS-29/tk cells may be clinically useful for BAL therapy.
Optical properties of the ZnSe nanocrystals embedded in PMMA matrix

In this paper we report linear and nonlinear optical properties of the thin films based on nanocrystals ZnSe embedded in centrosymmetric matrix PMMA, deposited by spin coating technique. Absorption and emission spectroscopy are shown respectively a blue shift and a strong band emission near the band gap of bulk material ZnSe, which is tunable with particles size. Blue shift of the absorption edge used to evaluate the average size of nanoparticles by using the E.M. A model. The size of NCs of ZnSe was estimated to 1.98 nm, compared to the exciton Bohr radius of bulk material. We established a strong quantum confinement state for the NCS ZnSe. Using Nd:YAG laser at 1064 nm in picoseconds regime, Second order susceptibilities were measured by SHG technique. The obtained value was four order of magnitude larger compared with the bulk (ZnSe) value.
Factors which Influence Customers' Intention to Switch from Call-Based Driver-for-hire Services to App-Based Driver-for-hire Services Based on Online to Offline (O2O) Business Model: Focusing on Kakao Driver service

Online-to-offline (O2O) commerce is the new trend that merges online commerce with traditional industries in various fields. The primary purpose of this paper is to find out which factors influence customers’ intention to switch from call-based driver-for-hire services to O2O app-based services. This study used variables and factors based on Theory
Investment Technology for Trading Business: Delineating Requirements, Processes, and Design Decisions for Order-Management Systems

7/1/2007 Outline 8/25/2007 First Draft 12/30/2007 Final Research Documented 1/15/2008 Final Feedback Revisions 2/25/2008 6 Investment Technology Acknowledgements I would like to acknowledge the generous contributions of extensive and thought­ provoking feedback and guidance provided primarily by Doug Hart and Don Archer. This work would not have been possible without their consistent and timely input regarding academic concerns, content, analytical and writing style, and overall approach to the topic. Throughout more than 5 years of working with Regis University’s MSCIT program, staff’s universal willingness to assist and accommodate a hurried working­adult student was nothing short of inspirational. I would also like to thank family and close friends for their support and encouragement as I progressed toward this personal milestone. Finally, heartfelt thanks go out to Eric Smith, Rob Howard, and their team at CodeSmith Tools; dedicated practitioners of software development owe a debt of gratitude to imaginations capable of such ideas. I thank you all. 7 Investment Technology Abstract The requirements and processes for building a robust order­management system (OMS) for trading of investments within financial services firms are investigated and enumerated. Requirements and process documentation are not readily available to members of the general public because they are considered a source of competitive advantage in a highly profitable industry. This paper provides single­source documentation of those requirements and processes in the context of the Vested OMS application, which was constructed specifically to meet industry needs in this area. This paper describes in detail the core functionality investment businesses currently demand and the software development techniques used to construct a core system to meet those demands.The requirements and processes for building a robust order­management system (OMS) for trading of investments within financial services firms are investigated and enumerated. Requirements and process documentation are not readily available to members of the general public because they are considered a source of competitive advantage in a highly profitable industry. This paper provides single­source documentation of those requirements and processes in the context of the Vested OMS application, which was constructed specifically to meet industry needs in this area. This paper describes in detail the core functionality investment businesses currently demand and the software development techniques used to construct a core system to meet those demands. 8 Investment Technology
The Dhandho Investor The Low Risk Value Method To High Returns

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Genetics of Polycyclic Aromatic Hydrocarbon Metabolism in Diverse Aerobic Bacteria

Polycyclic aromatic hydrocarbons (PAHs), which consist of two or more fused aromatic rings, are widespread in the environment and persist over long periods of time. The decontamination of a PAH-polluted environment is of importance because some PAHs are toxic, mutagenic, and carcinogenic and therefore are health hazards. As part of the efforts to establish remediation processes, the use of aerobic bacteria has been extensively studied, and both enzymologic and genetic studies are underway for the purpose of effective biodegradation. In the last two decades, one highly conserved group of PAH-catabolic genes from Pseudomonas species, called the nah-like genes, has been well investigated, and much has been found, including the structure-function relationships and the evolutionary trails of the catabolic enzymes. However, recently, PAH-catabolic genes, which are evolutionarily different from the nah-like genes, have been characterized from both Gram-negative bacteria other than Pseudomonas species and Gram-positive bacteria, and the information about these genes is expanding. This review is an outline of genetic knowledge about bacterial PAH catabolism.
europrotective effect of morroniside on focal cerebral ischemia in rats

Cornus officinalis Sieb. et Zucc. , known as Shan-zhu-yu in Chinese, has been used to treat cerebrovascular disease and diabetes in Traditional Chinese Medicine for a long time and morroniside is the main component of Shan-zhu-yu. In this study, we examined whether morroniside could protect ischemia/reperfusion-induced brain injury by minimizing oxidative stress and anti-apoptosis. Morroniside was intragastrically administered to rats in doses of 30, 90 and 270 mg/kg/day, starting 3 h after the onset of middle cerebral artery occlusion. The behavioral test was performed by using the Zea–Longa scores, Prehensile Traction score and Ludmila Belayer score. Rats were sacrificed 3 days after ischemia occurred. The infarction volume of brain was assessed in the brain slices stained with 2,3,5-triphenyl tetrazolium chloride. Cortex tissues were also used for determination of malondialdehyde levels, glutathione levels and superoxide dismutase. The treatment with morroniside significantly improved Zea–Longa scores and Prehensile Traction score at the doses of 30, 90 and 270 mg/kg, increased europrotection Ludmila Belayer score and reduced the infarction volume at the doses of 90 and 270 mg/kg. Morroniside (30, 90 and 270 mg/kg) treatment significantly decreased the level of malondialdehyde and caspase-3 activity by colorimetric analysis in ischemic cortex tissues. Morroniside (270 mg/kg) treatment significantly increased the content of glutathione, enhanced the activity of superoxide dismutase, but decreased the caspase-3 expression by Western-blot analysis in ischemic cortex tissues. These findings demonstrated that morroniside could notably protect the brain from damage induced by focal cerebral ischemia mor which might be related to
What Does the Speaker Embedding Encode?

Developing a good speaker embedding has received tremendous interest in the speech community. Speaker representations such as i -vector, d -vector have shown their superiority in speaker recognition, speaker adaptation and other related tasks. However, not much is known about which properties are exactly encoded in these speaker embeddings. In this work, we make an in-depth investigation on three kinds of speaker embeddings, i.e. i -vector, d -vector and RNN/LSTM based sequence-vector ( s -vector). Classiﬁcation tasks are carefully designed to facilitate better understanding of these encoded speaker representations. Their abilities of encoding different properties are revealed and compared, such as speaker identity, gender, speaking rate, text content and channel information. Moreover, a new architecture is proposed to integrate different speaker embed-dings, so that the advantages can be combined. The new advanced speaker embedding ( i-s -vector) outperforms the others, and shows a more than 50% EER reduction compared to the i -vector baseline on the RSR2015 content mismatch trials.
On the Performance of Active versus Passive Emerging Markets Equities Funds

In this note we evaluate the performance of active and passive emerging markets equities (EME) funds. In the first section, we investigate if it is possible to identify active EME funds that systematically outperform passive benchmark indexes. This section is based on a more extensive paper by Joop Huij and Thierry Post. In the next section, we examine the performance of passive EME funds, focusing on whether these funds succeed in their objective to closely track the return of a passive benchmark index. This section is based on a more extensive paper by David Blitz and Joop Huij.