Miracle-dz/UniFAR-FTUs huggingface dataset:
White Kids: Growing Up with Privilege in a Racially Divided America

form anything fundamental about neoliberalism. At the same time, they signal something interesting about how the gig economy may be reshaping productivity discourse. Counterproductive is an important example of how some of the most creative research in the sociology of work is being conducted inside tech companies. At the same time, the book sometimes skirts topics of intense interest to sociologists. Though it focuses on the spiritual dimension of productivity, for example, it makes only passing connection to Weber. How does the turn to quasiBuddhist practices connect to the history of the Protestant ethic and conversations around the ‘‘new’’ spirit of capitalism? More curious is the book’s conclusion, which outlines eight ‘‘principles for postwork productivity’’ that can ‘‘move our aspirations . from the corporate to the collective interest’’ and prioritize ‘‘practices of selflessness and care’’ (p. 138). This is a laudable vision shared by many sociologists, but the book does not engage with the many existing concrete proposals for achieving it. How ought we to think about universal basic income, collective organizing among gig workers, platform cooperativism, or policy ideas that constrain the tech companies pioneering exploitative productivity? How might companies such as Intel reimagine disruption, automation, fast failure, and risk in ways that are more responsible in an age of massive economic inequality? Given that Gregg has compellingly addressed these questions in her popular writing, the lack of engagement in this more academic text was noticeable. If you have ever felt simultaneously thrilled and disgusted with yourself at mastering your to-do list, Counterproductive can help explain why. It is an excellent resource for anyone wanting to explore the cultural meanings of today’s technological tools for managing our time and, ultimately, ourselves.
Ubiquitin ligase component LRS1 and transcription factor CrHy5 act as a light switch for photoprotection in Chlamydomonas

Survival under excess light conditions requires the light-induced accumulation of protein LHCSR3 and other photoprotection factors, to enable efficient energy-dependent quenching in the green microalga Chlamydomonas reinhardtii. Here, we demonstrate that the high light-tolerant phenotype of mutant hit1 is caused by a de-repression of promoters belonging to photoprotection genes, which in turn results from an inactivation of the E3 ubiquitin ligase substrate adaptor LRS1. Transcriptome analyses of hit1 revealed massive alterations of gene expression modulation as a consequence of perturbed LRS1 function, indicating its role as a crown regulator. In conjunction with random forest-based network modeling, these transcriptome analyses predicted that LRS1 controls photoprotection gene expression via an algal HY5 homolog as its prime transcription factor target. CrHY5 binds to T-box elements present in the promoters of these genes and its inactivation in the hit1 mutant via CRISPR-Cas9 genome editing, confirmed the regulatory connection between LRS1 and CrHY5, predicted by the network analysis.
Relative risk factors of patients with coronary heart disease combined with renal artery stenosis

Objective To investigate the risk factors of atherosclerotic renal artery stenosis (ARAS) in patients with coronary heart disease. Methods Six hundred and seventy-seven patients with suspected or certainly diagnosed as coronary heart disease consecutively underwent selective coronary angiography and non-selective renal artery angiography during May to Sep. 2016 in the Department of Cardiology of General Hospital of Shenyang Military Region. According to the degree of renal artery stenosis, the subjects were divided into renal artery normal group, renal artery slight stenosis group (renal artery stenosis <50%) and renal artery obvious stenosis group (renal artery stenosis ≥50%). Both univariate and multivariate logistic regression analysis were used to study the independent risk predictors of ARAS. Results By analysis of clinical data, it was found that age, systolic blood pressure, pulse pressure and creatinine level were higher in patients with different degrees of renal artery stenosis than in renal artery normal group (P<0.05). There were significant differences in different degrees of renal artery stenosis groups in female, hypertension, left main coronary artery (P<0.05). The proportion of coronary double vessel lesions was higher in renal artery slight stenosis group than in renal artery normal group (P<0.05). Age, pulse pressure and creatinine level were significantly higher in renal artery obvious stenosis group than in the other two groups (P<0.05). Peripheral vascular disease, left main coronary artery disease, single coronary artery and three vessel disease were significantly higher than that in other two groups (P<0.05). The incidence of renal artery obvious stenosis was 18.9% in patients with renal artery obvious stenosis, and was 16.7% in renal arteries slight stenosis group. By univariate and multivariate Logistic regression analysis, age, female, peripheral vascular disease, and multivessel coronary artery disease were independent risk factors for ARAS. Conclusion Renal artery angiography should be routinely performed for patients with coronary artery disease undergoing coronary angiography to identify ARAS, especially for elderly and female patients associated with peripheral vascular disease. DOI: 10.11855/j.issn. 0577-7402.2017. 12.10
Country Image Effects in the Era of Protectionism

Abstract The research presented in this article examines the effects of protectionist measures on the perceptions that consumers of a targeted country form of the country having adopted these measures as well of other countries not directly involved in the conflict. An experiment was conducted in which 148 Canadian adult consumers were informed that Germany had announced its decision to impose import tariffs on Canadian products. Two types of protectionist measures were considered, either initiated by Germany (i.e., proactive context) or as a response to similar measures adopted by Canada (i.e., reactive context). Consumers’ perceptions concerned the quality of products made in Germany, its image as a travel destination, and as a place to live. These perceptions were also obtained for three European countries differing with respect to their psychic distance with Germany; Austria (shortest distance), France (medium distance), and Spain (greatest distance). The results show that consumers’ perceptions depend on the type of protectionist measures adopted (proactive versus reactive), primarily among consumers interested in international economic news. Reactive protectionist measures were perceived as more legitimate than proactive measures and, in turn, legitimacy had a negative effect on the degree to which consumers developed situational political animosity toward Germany and, consequently, more negative country perceptions. These results were shown to spill over other countries as a function of their psychic distance with Germany. Implications for firms involved in global trading and for governments are derived from these results.
Development of the Esophagus and Stomach

Epithelial components of the organs of the digestive system are derived from the endoderm, whereas connective tissue and muscle components are derived from the mesoderm. At the 3rd-4th week of development, as a result of cephalocaudal and lateral foldings of the embryo, a portion of the endoderm-lined yolk sac cavity is incorporated in the embryo to form the primitive gut. Primitive gut is composed of four main regions: pharyngeal gut, foregut, midgut, and hindgut. The esophagus and stomach are derived from the foregut. The development of the esophagus is characterized by lengthening, widening, thickening, and histological changes. The development of the stomach is characterized by widening, thickening, and histological changes as well as positional changes. In the present study, we tried to review the morphological and functional development of the esophagus and stomach with the aid of pictures obtained from various stages of prenatal and postnatal development of the organs of rats. Previous reviews lack information on both histological and functional development of the organs.
Social Trust and Open Innovation in an Informal Economy: The Emergence of Shenzhen Mobile Phone Industry

This study examines how social trust facilitates firms’ collaborative efficiency in an informal economy. We extend the open innovation theory to explain the straightforward role of social trust in the Shenzhen mobile phone industry. This single case study yields two principal findings. First, social trust fosters the efficient integration of value chains for mobile phone development. Four types of informal entrepreneurs with high social trust built on homogenous sanctioned ethnic groups (i.e., Fujian, Hunan, Chaoshan, and Wenzhou) collaboratively conform to the chip vendors, independent design houses, integrators, manufacturers and channel retailers in the Shenzhen mobile phone industry. These four groups of informal entrepreneurs achieve ethnic legitimacy by organizing the value chains with mobile feature phones built on Shenzhen mobile phone modes. Second, social trust among the four sanctioned ethnic groups is a critical determinant for shortening the time-to-market of new products and catalyzes product specialization to effectively respond to market needs in the Shenzhen mobile phone industry. Finally, we discuss the implications of our findings for research on social trust and open innovation in informal institutions.
VP190 A Review Of Best Practices In Five Mental Disorders In Youth

INTRODUCTION: In order to support service planning of the youth program of the East of Montreal Health and Social Services Board, and potentially of the other twenty-five programs across the Quebec province, our hospital-based Health Technology Assessment (HTA) unit was asked to bring evidence of the effective interventions for five most common mental disorders in children and young populations, namely anxio-depressive disorders, attention deficit and hyperactivity disorder, oppositional and conduct disorders, substance abuse disorders, and suicide attempts. METHODS: A review of reviews was conducted for the five disorders in young populations aged 6 to 25 years. This was based exclusively on systematic reviews and meta-analysis of a minimum two randomized-controlled trials. The review was completed with examples of Quebec's good practices in youth mental health gathered from personal research experience of clinical researchers involved in the project. The project involved collaboration with three other hospital units and provincial HTA agencies. RESULTS: No review supporting screening and early detection for the five disorders was identified. Prevention, however, was better covered in the literature, and a clear distinction was made between universal, targeted and indicated interventions. In general, targeted and indicated prevention interventions were effective in the case of anxio-depressive (1) and substance use disorders, while universal prevention strategies seemed to reduce suicide attempts and suicide ideation (2). Effective treatments also exist for these mental disorders. In general, psychotherapies dominated for anxio-depressive and substance use disorders; parental skills dominated in oppositional disorders, whilst pharmacological treatment dominated in attention deficit and hyperactivity disorder (3). Evidence was limited for suicide attempts. The overview of Quebec's good practices allowed identification of interventions or practices already in use in the province. CONCLUSIONS: The review summarized effective interventions for five most common mental disorders in young populations. It also permitted to identify several research gaps, and therefore research recommendations were formulated for the province's health research agency.
The significance of context: autonomy and curriculum reform in rural schools

In the large volume of research on curriculum reform, very little attention is paid to the implications of geographical location, yet, this can be significant. The current curriculum reform process in Wales has presented an opportunity for schools to radically change their practice. While rural schools have welcomed this opportunity, they face challenges unrecognised by the wider educational establishment. This article presents a view of the reform process from school level, using data from semi-structured interviews with teachers working on curriculum reform. Thematic analysis reveals enthusiastic responses to reform and the greater autonomy it promises. There are, however, challenges, including concerns about staffing, access to professional learning and learners’ access to extra-curricular learning. The research demonstrates that while rural schools face challenges unique to their location, their response to reform demonstrates a capacity for independent action in line with the aspirations of the new curriculum.
Incidence of diabetic eye disease in accordance with duration, glycemic control, blood and ocular pressure

SummaryIntroduction. Diabetic retinopathy remains the leading cause of visual disability and blindness among professionally active adults in economically developed societies, which is of particular concern because the prevalence and incidence of diabetes mellitus is ex pected to increase sharply during the next decade. There are sev eral known factors responsible for the development of diabetic retinopathy, duration of disease and blood sugar level being the most important ones. Material and Methods . Prospective study of 280 diabetic patients (diabetes mellitus type 2) divided into 3 groups according to the duration of diabetes mellitus. All diabetic patients underwent complete ophthalmological examination in artificial mydriasis and optic coherence tomography. A full medical history included patient age, the time elapsed from diabetes diagnosis, cur rent treatment of diabetes, presence of hypertension and glycemic control assessed by glycosylated hemoglobin measurement. Results. The mean age of patients was 63.5 years (SD±6.5, range 57-70 years). Mean duration of diabetes was 7.3 years in group I, 12.4 years in group II and 17.2 years in group III. The average value of glyco sylated hemoglobin was 6.58% in the group I, 7.64% in the group II and 8.29% in the third group of patients. No statistically significant difference in intraocular pressure and the level of blood pressure were found among groups. Cataract was present in 104 patients (37.1%). Complications related to diabetes among all patients in cluded in our study were: nonproliferative diabetic retinopathy in 48.5%, proliferative diabetic retinopathy in 25.7% and diabetic macular edema in 22.5% of patients. Conclusion. The duration of diabetes is one of the most significant factors for the development of diabetic maculopathy and the progression from nonproliferative to its proliferative stage. There is significantly higher incidence of proliferative diabetic retinopathy and diabetic macular edema in patients with increased serum level of glycosylated hemoglobin. Diabetes accompanied by hypertension is related to worsening of the clinical course of diabetic eye diseases and developing diabetic macular edema and proliferative diabetic retinopathy.
Overcoming potential barriers to investigating and treating myxomatous mitral valve disease

Diagnosing myxomatous mitral valve disease (MMVD) can be relatively straightforward. However, persuading owners to investigate and treat MMVD, and then maintain adherence to a therapeutic regimen can be significantly more challenging. While heart murmurs are most likely to be detected during the annual health check or booster consultation, recent evidence suggests this might not be an ideal time to discuss MMVD. This article reviews some of the potential barriers to owners following practitioners’ recommendations, and suggests some solutions.
Growth‐Factor Free Multicomponent Nanocomposite Hydrogels That Stimulate Bone Formation

Synthetic osteo‐promoting materials that are able to stimulate and accelerate bone formation without the addition of exogenous cells or growth factors represent a major opportunity for an aging world population. A co‐assembling system that integrates hyaluronic acid tyramine (HA‐Tyr), bioactive peptide amphiphiles (GHK‐Cu2+), and Laponite (Lap) to engineer hydrogels with physical, mechanical, and biomolecular signals that can be tuned to enhance bone regeneration is reported. The central design element of the multicomponent hydrogels is the integration of self‐assembly and enzyme‐mediated oxidative coupling to optimize structure and mechanical properties in combination with the incorporation of an osteo‐ and angio‐promoting segments to facilitate signaling. Spectroscopic techniques are used to confirm the interplay of orthogonal covalent and supramolecular interactions in multicomponent hydrogel formation. Furthermore, physico‐mechanical characterizations reveal that the multicomponent hydrogels exhibit improved compressive strength, stress relaxation profile, low swelling ratio, and retarded enzymatic degradation compared to the single component hydrogels. Applicability is validated in vitro using human mesenchymal stem cells and human umbilical vein endothelial cells, and in vivo using a rabbit maxillary sinus floor reconstruction model. Animals treated with the HA‐Tyr‐HA‐Tyr‐GHK‐Cu2+ hydrogels exhibit significantly enhanced bone formation relative to controls including the commercially available Bio‐Oss.
Software Vampp Bovino como instrumento de mediación dialógica entre el sector productivo bovino y la academia

El programa informático VAMPP Bovino es un paquete de apoyo a la toma de decisiones en fincas de ganado bovino, bubalino y porcino, originalmente desarrollado en la Universidad de Utrecht (Países Bajos), pero traído a Costa Rica, en 1986, por medio de un programa de cooperación internacional (MHO de los Países Bajos) a la Escuela de Medicina Veterinaria de la UNA. Aquí, en el Centro Regional de Informática para la Producción Animal Sostenible (CRIPAS), el programa se adaptó y validó a las condiciones productivas costarricenses, en primera instancia, para luego trascender fronteras y ubicarse en toda Centroamérica, México, el Caribe y varios países de Suramérica. Este proceso ha sido posible, en primer lugar, por el respaldo de la UNA a este proyecto que, de hecho, es el único en su tipo, en todo el mundo, que sobrevive una vez que el financiamiento MHO cesó; pero sin duda por el proceso de comunicación y diálogo constante con los actores de los distintos segmentos del sector productivo ganadero de Costa Rica –y de los otros países en donde se usa VAMPP–. Este proceso dialógico que ha recogido, y sigue recogiendo, el conocimiento y las experiencias de quienes realizan o son responsables de toda la cadena de producción, transformación y comercialización de los productos bovinos es el que hace posible su incorporación en un programa informático que ha beneficiado a más de dos mil productores en diversos países, especialmente más de 1 500 en Costa Rica, así como a todos los participantes de la cadena de producción, pero con especial efecto en el consumidor que tiene productos de buena calidad (alimento seguro) y en cantidad (seguridad alimentaria). VAMPP Bovino es un modelo de proyecto universitario exitoso, llevado bajo el respaldo de la UNA.
Unfocused ultrasound waves for manipulating andimaging microbubbles

With unfocused plane/diverging ultrasound waves, the capability of simultaneous sampling on each element of an array transducer has spawned a branch known as high-frame-rate (HFR) ultrasound imaging, whose frame rate can be two orders of magnitude faster than traditional imaging systems. Microbubbles are micron-sized spheres with a heavy gas core that is stabilized by a shell made of lipids, polymers, proteins, or surfactants. They are excellent ultrasound scatters and have been used as ultrasound contrast agents, and more recently researched as a mechanism for targeted drug delivery. With the Ultrasound Array Research Platform II (UARP II), the objective of this thesis was to develop and advance several techniques for manipulating and imaging microbubbles using unfocused ultrasound waves. These techniques were achieved by combining custom transmit/receiving sequencing and advanced signal processing algorithms, holding promise for enhanced diagnostic and therapeutic applications of microbubbles. A method for locally accumulating microbubbles with fast image guidance was first presented. A linear array transducer performed trapping of microbubble populations interleaved with plane wave imaging, through the use of a composite ultrasound pulse sequence. This technique could enhance image-guided targeted drug delivery using microbubbles. A key component of targeted drug delivery using liposome-loaded microbubbles and ultrasound is the ability to track these drug vehicles to guide payload release locally. As a uniquely identifiable emission from microbubbles, the subharmonic signal is of interest for this purpose. The feasibility of subharmonic plane wave imaging of liposome-loaded microbubbles was then proved. The improved subharmonic sensitivity especially at depth compared to their counterpart of bare (unloaded) microbubbles was confirmed. Following plane wave imaging, the combination of diverging ultrasound waves and microbubbles was investigated. The image formation techniques using coherent summation of diverging waves are susceptible to tissue and microbubble motion artefacts, resulting in poor image quality. A correlation-based 2-D motion estimation algorithm was then proposed to perform motion compensation for HFR contrast-enhanced echocardiography (CEE). A triplex cardiac imaging technique, consisting of B mode, contrast mode and 2-D vector flow imaging with a frame rate of 250 Hz was presented. It was shown that the efficacy of coherent diverging wave imaging of the heart is reliant on carefully designed motion compensation algorithms capable of correcting for incoherence between steered diverging-wave transmissions. Finally, comparisons were made between the correlation-based method and one established image registration method for motion compensation. Results show that the proposed correlation-based method outperformed the image registration model for motion compensation in HFR CEE, with the improved image contrast ratio and visibility of geometrical borders both in vitro and in vivo.
Environment affects specialisation of plants and pollinators

What determines whether or not a species is a generalist or a specialist? Evidence that the environment can influence species interactions is rapidly accumulating. However, a systematic link between environment and the number of partners a species interacts with has been elusive so far. Presumably, because environmental gradients appear to have contrasting effects on species depending on the environmental variable. Here, we test for a relationship between the stresses imposed by the environment, instead of environmental gradients directly, and species specialisation using a global dataset of plant-pollinator interactions. We found that the environment can play a significant effect on specialisation, even when accounting for community composition, likely by interacting with species’ traits and evolutionary history. Species that have a large number of interactions are more likely to focus on a smaller number of, presumably higher-quality, interactions under stressful environmental conditions. Contrastingly, the specialists present in multiple locations are more likely to broaden their niche, presumably engaging in opportunistic interactions to cope with increased environmental stress. Indeed, many apparent specialists effectively behave as facultative generalists. Overall, many of the species we analysed are not inherently generalist or specialist. Instead, species’ level of specialisation should be considered on a relative scale depending on where they are found and the environmental conditions at that location.