Miracle-dz/UniFAR-FTUs huggingface dataset:
Measuring the Effects of Risk and Cultural Dimensions on the Adoption of Online Stock Trading: A Developing Country Perspective

Online stock trading (OST) is a growing phenomenon across countries, yet there is a sparse literature focusing on the negative utilities (risks) that causing the low adoption. Drawing from perceived risk theory, this article attempts to fill the gap by identifying the influential risk factors that impede the acceptance of OST in a developing country, Pakistan. The study also applies the Hofstede cultural theory to ascertain the effects of cultural moderators on investors' usage behavior (UB). Based on structured questionnaire, 443 valid responses were received from current and potential investors. The model was tested using structural equation modeling through Smart-PLS. The results validate a negative and significant relationship between risk dimensions and investors' behavioral intentions (BI) to use OST. Especially time, financial, performance, privacy and opportunity cost risks are found having a negative impact on investors' BI. Moreover, the study finds that cultural dimensions, collectivism, and uncertainty avoidance, moderate the relationship between BI and UB.
High‐dose glucocorticoids for the treatment of ipilimumab‐induced hypophysitis is associated with reduced survival in patients with melanoma

It remains unclear whether high doses of glucocorticoids have a negative impact on the efficacy of checkpoint inhibitors. To control for the potential association between immune‐related adverse events (irAEs) and improved survival, this study examined a unique cohort of patients who had the same irAE treated with varying glucocorticoid doses.
An Insight into Rare Class Problem: Analysis and Potential Solutions

The class imbalance problem presents an important challenge to the data mining community, in which the number of examples of one class is more than the others. This problem is characterized by a different distribution of cases between all the classes. In this paper, our goal is to study the various challenges of class imbalance problem and provide a comparative study of the current development of research in learning from imbalanced data. We provide a thorough understanding of the nature of the problem, the methods used for data balancing, the learning objectives and assessment metrics used for getting measurable performance, the stated research solutions and the imbalanced problem in multiple classes. This paper highlights the significant opportunities and challenges in the field and provides potential future research directions in the class imbalance problem.
Characteristics of Cognitive Behavioral Therapy for Older Adults Living in Residential Care: Protocol for a Systematic Review

Background The prevalence rates of depressive and anxiety disorders are high in residential aged care settings. Older adults in such settings might be prone to these disorders because of losses associated with transitioning to residential care, uncertainty about the future, as well as a decline in personal autonomy, health, and cognition. Cognitive behavioral therapy (CBT) is efficacious in treating late-life depression and anxiety. However, there remains a dearth of studies examining CBT in residential settings compared with community settings. Typically, older adults living in residential settings have higher care needs than those living in the community. To date, no systematic reviews have been conducted on the content and the delivery characteristics of CBT for older adults living in residential aged care settings. Objective The objective of this paper is to describe the systematic review protocol on the characteristics of CBT for depression and/or anxiety for older adults living in residential aged care settings. Methods This protocol was developed in compliance with the recommendations of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). Studies that fulfill the inclusion criteria will be identified by systematically searching relevant electronic databases, reference lists, and citation indexes. In addition, the PRISMA flowchart will be used to record the selection process. A pilot-tested data collection form will be used to extract and record data from the included studies. Two reviewers will be involved in screening the titles and abstracts of retrieved records, screening the full text of potentially relevant reports, and extracting data. Then, the delivery and content characteristics of different CBT programs of the included studies, where available, will be summarized in a table. Furthermore, the Downs and Black checklist will be used to assess the methodological quality of the included studies. Results Systematic searches will commence in May 2018, and data extraction is expected to commence in July 2018. Data analyses and writing will happen in October 2018. Conclusions In this section, the limitations of the systematic review will be outlined. Clinical implications for treating late-life depression and/or anxiety, and implications for residential care facilities will be discussed. Trial Registration PROSPERO 42017080113; https://www.crd. york.ac. uk/PROSPERO/display_record. php? RecordID=80113 (Archived by WebCite at http://www.webcitation.org/70dV4Qf54) Registered Report Identifier RR1-10.2196/9902
Minimisation Of Network Covering Services With Predefined Centres

In this paper, we deal with a special version of the set covering problem, which consists in finding the minimum number of service centres providing specialized services for all customers (or larger units, such as urban areas) within a reasonable distance given by a threshold. If a suitable threshold is found that makes it possible to determine a feasible solution of the task, the task is transformed into a general set covering problem. In order to reflect the importance of the centers, we assign weights to them and, if some centers must be contained in the result, we can either add columns in the reachability matrix with link to these centres or add special constraints in the mathematical model. However, this is of a combinatorial nature and, because it belongs to the class of NP-hard problems, for a large instance of the problem, it cannot be used to find the optimal solution in a reasonable amount of time. In the paper, we present a solution that uses two heuristic methods: genetic algorithm and tabu search.
Gender Difference in the Association between Environmental Tobacco Smoke and Birth Weight in Africa

The adverse health effects of exposure to environmental tobacco smoke (ETS) on children are well-documented, and yet, gender difference in low birthweight among newborns whose mothers were exposed to ETS during pregnancy still remains contentious. We therefore explored the association between ETS exposure and risk of low birthweight, and further determined the gender difference in the association between exposure to ETS during pregnancy and birth weight in Africa. The Demographic Health Surveys of 23 African countries with information on 208,027 newborns were used. The associations between exposure to ETS and birth weight was estimated using multiple logistic regression models. Exposure to ETS increased the risk of low birthweight in Africa (adjusted odds ratio (OR) = 1.06; 95% Confidence Interval (CI): 1.02–1.10). A stratified analysis, by gender, revealed that male newborns whose mothers were exposed to ETS were 1.08 (95% CI: 1.02–1.14) times more likely to be low in birthweight than those whose mothers were not exposed, with those exposed weekly (adjusted OR = 1.17; 95% CI: 1.01–1.35) and daily (adjusted OR = 1.06; 95% CI: 1.01–1.12) being more likely to have low birthweight. Exposure to ETS is significantly associated with low birthweight in Africa, mainly among male newborns. Gender could possibly be a modifier, and hence, research on biological plausibility is necessary. Moreover, a public health promotion on behavioral changes is likely to have a positive impact on newborns’ health.
Violencia escolar en México: una exploración de sus dimensiones y consecuencias

Las escuelas, como otras instituciones, estan inmersas en entornos conflictivos. Por ello no resulta sorprendente que algunas formas de violencia social se repliquen en su interior. Sin embargo, la violencia escolar no es un simple reflejo de lo que ocurre en la sociedad, es tambien, a menudo, una institucion productora de violencia. Este trabajo analiza tres dimensiones de la violencia escolar -la violencia entre pares, la violencia institucional y la violencia de los entornos sociales-, asi como sus consecuencias sobre dos factores: 1) el bienestar subjetivo de los estudiantes y 2) la decision de salirse de la escuela. El analisis se realizo a partir de la informacion arrojada por 1 398 encuestas aplicadas a estudiantes de tercer ano de escuelas secundarias en diez grandes ciudades de diferentes regiones de la Republica Mexicana a finales de 2012.
ERP System Adoption Analysis Using TOE Framework in Permata Hijau Group (PHG) Medan

In this research, employee adoption intention is important consideration of successful ERP system implementation. The purpose of this research is to identify the important factors in Technology-Organization-Environment framework that affect ERP system adoption's intention. Online survey data were collected from 175 employees with active status from each department who had used ERP in PHG, Indonesia. The research data was collected through simple random sampling method and applying SEM in AMOS 24. The results of this article proves that technology readiness, organization size, and external support significantly influence ERP system adoption intention. Compatibility, relative advantage, complexity, top management support, business operation, and competition pressure have no significant influence on ERP system adoption intention. Thus, it can be concluded that ERP system adoption's intention is important to enhance corporate competitive advantage. Adopted ERP system can be developed continuously by involving employees to achieve information technology and business strategy within company.
How to write an article: An introduction to basic scientific medical writing

An original scientific article published in a peer-reviewed professional journal of repute provides great personal satisfaction, adds stature and endows professional respectability to contributing authors. Various types of surgical publications that exist nowadays are case report, cohort study, case–control study, randomised controlled trial narrative review, systematic review, Cochrane review, meta-analysis, editorials and leading articles. A study/research protocol is a standardised document, common to all research projects that typically comprise study objectives, study design, selection of participants, study intervention, study evaluations, safety assessments, statistics and participant rights committees. Once the study protocol is completed and reviewed, it is submitted to the local Institutional Review Board/Institutional Ethics Committee for approval. An outline of the levels of evidence and grades of recommendation is available from the Centre for evidence-based medicine at the University of Oxford. A standardised, structured template exists for scientific presentations in the field of medicine which is also followed in medical writing and publications Introduction Methods Results And Discussion (IMRAD). Instructions to authors would normally include reference to International Committee of Medical Journal Editors and Committee on Publication Ethics guidelines for good and ethical publication practice. It is strongly advised to follow the recommended guidelines appropriate for the published study.
Effect of User Sessions on the Heuristic Usability Method

Heuristic evaluation (HE) is a widely used method for assessing software systems. Several studies have sought to improve the effectiveness of HE by developing its heuristics and procedures. However, few studies have involved the end-user, and to the best of the authors’ knowledge, no HE studies involving end-users with non-expert evaluators have been reported. Therefore, the aim of this study is to investigate the impact of end-users on the results obtained by a non-expert evaluator within the HE process, and through that, to explore the number of usability problems and their severity. This article proposes introducing two sessions within the HE process: a user exploration session (UES-HE) and a user review session (URS-HE). The outcomes are compared with two solid benchmarks in the usability-engineering field: the traditional HE and the usability testing (UT) methods. The findings show that the end-user has a significant impact on non-expert evaluator results in both sessions. In the UES-HE method, the results outperformed all usability evaluation methods (UEMs) regarding the usability problems identified, and it tended to identify more major, minor, and cosmetic problems than other methods.
Predictive factors of survival in a surgical series of metastatic epidural spinal cord compression and complete external validation of 8 multivariate models of survival in a prospective North American multicenter study

This study was designed to identify preoperative predictors of survival in surgically treated patients with metastatic epidural spinal cord compression (MESCC), to examine how these predictors are related to 8 prognostic models, and to perform the first full external validation of these models in accordance with the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) statement.
HO‐1 regulates the function of Treg: Association with the immune intolerance in vitiligo

In vitiligo, cutaneous depigmentation is accompanied by increased T cell cytolytic activity targeting melanocytes, indicating that autoimmune tolerance is disrupted. The inhibited amount and function of Tregs have been indicated to be involved in the autoimmune intolerance in vitiligo, however, with the conclusion still controversial and the involved mechanism unknown. In this study, we explored the molecular and cellular alterations accounting for the impaired Treg response in vitiligo. Our results showed that the amount of Tregs was drastically reduced in peripheral blood of active vitiligo patients. Furthermore, the immunoregulatory function of Tregs was attenuated, with lower expression of CTLA4, IL‐10 and TGF‐β. Moreover, the expression of HO‐1, a functional modulator of Tregs, was decreased in vitiligo Tregs, and the concentrations of HO‐1 metabolites, including bilirubin, CoHb and iron, were correspondingly decreased in serum of vitiligo patients. In addition, we treated the Tregs from vitiligo patients with Hemin, an agonist of HO‐1, and found that enhanced HO‐1 expression restored the function of Tregs by up‐regulating IL‐10 expression. Our study demonstrates the essential role of HO‐1 in the impaired Treg response in vitiligo and indicates the potential of HO‐1 as a therapeutic target in vitiligo management.
“Two Rules of Speciation” revisited

In the famous last paragraph of On the Origin of Species, Darwin compared the "fixed law of gravity", which causes the Earth to orbit the Sun, with the evolution of species by natural selection. This may be the first recorded case in biology of "physics envy": the view that the proper task of the life sciences-in Darwin's case, evolutionary biology-is to emulate physics by establishing general laws and working out their consequences. Although we don't speak of "laws" in biology, we do have lawlike generalizations, including the near-universality of the genetic code and the mechanism for translating DNA and RNA into proteins. This article is protected by copyright. All rights reserved.
Impact of underlying plaque type on strut coverage in the early phase after drug-eluting stent implantation

Background The aim of this study was to investigate whether the underlying plaque type affects the neointimal coverage after drug-eluting stent implantation. Methods A total of 1793 struts in 22 zotarolimus-eluting stents were assessed using optical coherence tomography imaging within 3 months of implantation. Neointimal coverage was evaluated within 5 mm from each stent edge on cross-sectional optical coherence tomography images at every 1-mm interval. The percentage of struts covered by neointima was compared among the normal segment group, the fibrous plaque group, and the lipid plaque group on the basis of the underlying plaque type. Results The percentage of covered strut was significantly lower in the normal segment group than in the fibrous plaque group (35.9±30.2 vs. 57.1±31.0%, P<0.05) and the lipid plaque group (vs. 64.7±23.5%, P<0.01). The neointima was significantly thinner in the normal segment group than in the lipid plaque group (19.0±22.3 vs. 32.0±18.8 &mgr;m, P<0.01). The percentage of struts on the normal segment was significantly higher in cross-sections with a ratio of uncovered to total struts per section more than 0.3 than in cross-sections with a ratio up to 0.3 (32.4±31.7 vs. 19.5±33.8%, P<0.01). Conclusion Struts on the normal segment were less covered and had thinner neointima than struts on the lipid plaque at the stent edge within 3 months after zotarolimus-eluting stent implantation. Caution should be exercised when implanting longer drug-eluting stents to achieve uniform strut coverage in the early phase.
Development of a Software that Supports Multimodal Learning Analytics: A Case Study on Oral Presentations

Learning Analytics is the intelligent use of data generated from students with the objective of understanding and improving the teaching and learning process. Currently, there is a lack of tools to measure the development of complex skills in real classroom environments that are flexible enough to add and process data from different sensors and oriented towards a massive public. Based on this finding, we developed a free software system that permits to capture and to visualize a set of 10 body postures using the Microsoft Kinect sensor, along with the ability to track custom body postures and data from other sensors. The developed tool was validated by means of precision and usability tests. Furthermore, with the goal of demonstrating the potential of incorporating this type of software into the classroom, the software was used as a tool to give feedback to the teacher and to the students at the moment of giving and evaluating oral presentations. Also, a clustering analysis of data gathered from 45 student presentations indicate that presentations on similar topics with also similar complexity levels can be successfully discriminated.
Der Einsatz von Idarucizumab bei intrazerebraler Blutung – Ein Fallbericht

Zusammenfassung Anamnese und klinischer Befund Aufnahme eines 82-jährigen Patienten mit Verdacht auf zerebrale Blutung nach häuslichem Sturz unter Dauerantikoagulation mit Dabigatran wegen Vorhofflimmern. Untersuchungen Die kraniale Computertomografie zeigte beidseitige chronische Subduralhämatome mit frischen Blutanteilen eines ausgedehnten, linksseitigen Subduralhämatoms und Mittellinienverlagerung. Die Laboranalyse ergab eine nur mäßig hohe Dabigatran-Konzentration bei durchlaufender Thrombinzeit. Diagnose Sturzbedingte intrazerebrale Blutung und chronisches Subduralhämatom unter Antikoagulation. Therapie und Verlauf Präoperative Gabe von Idarucizumab zur Antagonisierung von Dabigatran und neurochirurgische Hämatom-Evakuation mit rückläufiger Mittellinienverlagerung. Heparinisierung und Wiederaufnahme der Dabigatran-Behandlung nach Rehabilitation in klinisch stabilem Verlauf bei neurologisch geringgradigen Residuen.
A Comment on "Cross-Platform Identification of Anonymous Identical Users in Multiple Social Media Networks"

The Friend Relationship-Based User Identification (FRUI) algorithm is considered to be the ideal method. However, if the seed User Matched Pairs (UMPs) were not suitable, FRUI would stop early due to Controversial UMPs. We highlight this gap and propose a minor change to make FRUI a more general identification algorithm.
Restructurations du centre et conflits des périphéries. L’échec des projets urbains face au retrait des armées en Italie

A travers une analyse des projets d’amenagement pour la reconversion des sites militaires dans trois villes italiennes – Rome, Tarente et Udine –, cet article contribue aux debats sur l’evolution des relations entre les gouvernements urbains et l’Etat depuis les annees 1990. Il montre l’echec des negociations autour des projets urbains et l’emergence de nouveaux conflits entre les villes et l’Etat. Alors que les travaux sur les villes ont mis l’accent sur la construction d’accords localises dans la production des politiques urbaines, le cas des sites militaires amene a defendre l’idee qu’un modele territorial decentralise, mais egalement structure par des logiques etatiques de retraits et de coupes budgetaires, produit de nouveaux conflits entre centre et peripherie.
Dyslexia and dyscalculia are characterized by common visual perception deficits

ABSTRACT A number of studies have investigated the cognitive deficits underlying dyslexia and dyscalculia. Yet, it remains unclear as to whether dyslexia and dyscalculia are associated with the common visual perception deficits. The current investigation analyzed cognitive performance in children with dyslexia, dyscalculia, comorbidity, and typically developing subjects. The results showed that children with dyslexia, dyscalculia and comorbidity exhibited common deficits in numerosity processing and visual perception. Furthermore, visual perception deficits accounted for deficits in numerosity processing in all three groups. The results suggest that visual perception deficits are a common cognitive deficit underlying both developmental dyslexia and dyscalculia.
Exploring the Effect of Distance: An Experimental Investigation of Virtual Collaboration, Social Loafing, and Group Decisions

Contemporary businesses are rapidly embracing virtual collaboration as a flexible, cheaper, and more efficient method for conducting group work. Past research has shown, however, that virtual groups operate quite differently than face‐to‐face groups. In this study, Social Impact Theory provides a framework to investigate whether virtual collaboration heightens social loafing—the tendency for individuals to contribute less than full effort to a group. The theory predicts that member distance, inherent in virtual collaboration, increases the propensity of group members to loaf, and decreases group performance. Two hundred seventy‐nine participants assigned to face‐to‐face or virtual groups completed a business resources allocation task. Results suggest that virtual collaboration negatively affects group performance and that social loafing behavior may partially explain this result. The findings imply that organizations should carefully consider whether virtual collaboration can be seamlessly substituted for.