Miracle-dz/UniFAR-FTUs huggingface dataset:
Phenotypic Selection in Ornamental Breeding: It's Better to Have the BLUPs Than to Have the BLUEs

Plant breeders always face the challenge to select the best individuals. Selection methods are required that maximize selection gain based on available data. When several crosses have been made, the BLUP procedure achieves this by combining phenotypic data with information on pedigree relationships via an index, known as family-index selection. The index, estimated based on the intra-class correlation coefficient, exploits the relationship among individuals within a family relative to other families in the population. An intra-class correlation coefficient of one indicates that the individual performance can be fully explained based on the family background, whereas an intra-class correlation coefficient of zero indicates the performance of individuals is independent of the family background. In the case the intra-class correlation coefficient is one, family-index selection is considered. In the case the intra-class correlation coefficient is zero, individual selection is considered. The main difference between individual and family-index selection lies in the adjustment in estimating the individual's effect depending on the intra-class correlation coefficient afforded by the latter. Two examples serve to illustrate the application of the BLUP method. The efficiency of individual and family-index selection was evaluated in terms of the heritability obtained from linear mixed models implementing the selection methods by suitably defining the treatment factor as the sum of individual and family effect. Family-index selection was found to be at least as efficient as individual selection in Dianthus caryophyllus L. , except for flower size in standard carnation and vase life in mini carnation for which traits family-index selection outperformed individual selection. Family-index selection was superior to individual selection in Pelargonium zonale in cases when the heritability was low. Hence, the pedigree-based BLUP procedure can enhance selection efficiency in production-related traits in P. zonale or shelf-life related in D. caryophyllus L.
Methodology for Monitoring Aerial Emissions from Highways

In this paper, we propose a methodology for real-time vehicle emission monitoring near major highways using fixed and mobile sensor units. We use the U.S. Environmental Protection Agency (EPA) Motor Vehicle Emission Simulator (MOVES) to estimate the emission levels of the transportation-related air pollutants such as carbon monoxide, oxides of nitrogen, methane and hydrocarbons. We aim to correlate the collected real-time data and the MOVES simulator output emission levels. Based on the collected data from the deployed sensors, we will further calibrate the output of the MOVES simulator to provide accurate pollutant emission levels for accurate prediction of air quality near major highways.
Physical Activity Comparison Between Body Sides in Hemiparetic Patients Using Wearable Motion Sensors in Free-Living and Therapy: A Case Series

Background: Physical activity (PA) is essential in stroke rehabilitation of hemiparetic patients to avoid health risks, and moderate to vigorous PA could promote patients' recovery. However, PA assessments are limited to clinical environments. Little is known about PA in unguided free-living. Wearable sensors could reveal patients' PA during rehabilitation, and day-long long-term measurements over several weeks might reveal recovery trends of affected and less-affected body sides. Methods: We investigated PA in an observation study during outpatient rehabilitation in a day-care center. PA of affected and less-affected body sides, including upper and lower limbs were derived using wearable motion sensors. In this analysis we focused on PA during free-living and clinician guided therapies, and investigated differences between body-sides. Linear regressions were used to estimate metabolic equivalents for each limb at comparable scale. Non-parametric statistics were derived to quantify PA differences between body sides. Results: We analyzed 102 full-day movement data recordings from eleven hemiparetic patients during individual rehabilitation periods up to 79 days. The comparison between free-living and clinician guided therapy showed on average 16.1 % higher PA in the affected arm during therapy and 5.3 % higher PA in the affected leg during therapy. Average differences between free-living and therapy in the less-affected side were below 4.5 %. Conclusion: We analyzed PA of patients with a hemiparesis in two distinct rehabilitation settings, including free-living and clinician guided therapies over several weeks and compared MET values of affected and less-affected body sides. In particular, we investigated PA using individual regression models for each limb. We demonstrated that wearable motion sensors provide insights in patient's PA during rehabilitation. Although, no clear PA trends were found, our analysis showed patients' tendency to sedentary behavior, confirming previous lab study results. Our PA analysis approach could be used beyond clinical rehabilitation to devise personalized patient and limb-specific exercise recommendations in future remote rehabilitation.
Loop Optimization Framework

The LLVM compiler framework supports a selection of loop transformations such as vectorization, distribution and unrolling. Each transformation is carried-out by specialized passes that have been developed independently. In this paper we propose an integrated approach to loop optimizations: A single dedicated pass that mutates a Loop Structure DAG. Each transformation can make use of a common infrastructure such as dependency analysis, transformation preconditions, etc.
The Global Hepatitis B Virus Genotype Distribution Approximated from Available Genotyping Data

Hepatitis B virus (HBV) is divided into nine genotypes, A to I. Currently, it remains unclear how the individual genotypes contribute to the estimated 250 million chronic HBV infections. We performed a literature search on HBV genotyping data throughout the world. Over 900 publications were assessed and data were extracted from 213 records covering 125 countries. Using previously published HBV prevalence, and population data, we approximated the number of infections with each HBV genotype per country and the genotype distribution among global chronic HBV infections. We estimated that 96% of chronic HBV infections worldwide are caused by five of the nine genotypes: genotype C is most common (26%), followed by genotype D (22%), E (18%), A (17%) and B (14%). Genotypes F to I together cause less than 2% of global chronic HBV infections. Our work provides an up-to-date analysis of global HBV genotyping data and an initial approach to estimate how genotypes contribute to the global burden of chronic HBV infection. Results highlight the need to provide HBV cell culture and animal models that cover at least genotypes A to E and represent the vast majority of global HBV infections to test novel treatment strategies.
Cellular Phenotype Plasticity in Cancer Dormancy and Metastasis

Cancer dormancy is a period of cancer progression in which residual tumor cells exist, but clinically remain asymptomatic for a long time, as well as resistant to conventional chemo- and radiotherapies. Cellular phenotype plasticity represents that cellular phenotype could convert between epithelial cells and cells with mesenchymal traits. Recently, this process has been shown to closely associate with tumor cell proliferation, cancer dormancy and metastasis. In this review, we have described different scenarios of how the transition from epithelial to mesenchymal morphology (EMT) and backwards (MET) are connected with the initiation of dormancy and reactivation of proliferation. These processes are fundamental for cancer cells to invade tissues and metastasize. Recognizing the mechanisms underlying the cellular phenotype plasticity as well as dormancy and targeting them is likely to increase the efficiency of traditional tumor treatment inhibiting tumor metastasis.
Local search breaks 1.75 for Graph Balancing

Graph Balancing is the problem of orienting the edges of a weighted multigraph so as to minimize the maximum weighted in-degree. Since the introduction of the problem the best algorithm known achieves an approximation ratio of $1.75$ and it is based on rounding a linear program with this exact integrality gap. It is also known that there is no $(1.5 - \epsilon)$-approximation algorithm, unless $\mathrm{P}=\mathrm{NP}$. Can we do better than $1.75$? We prove that a different LP formulation, the configuration LP, has a strictly smaller integrality gap. Graph Balancing was the last one in a group of related problems from literature, for which it was open whether the configuration LP is stronger than previous, simple LP relaxations. We base our proof on a local search approach that has been applied successfully to the more general Restricted Assignment problem, which in turn is a prominent special case of makespan minimization on unrelated machines. With a number of technical novelties we are able to obtain a bound of $1.749$ for the case of Graph Balancing. It is not clear whether the local search algorithm we present terminates in polynomial time, which means that the bound is non-constructive. However, it is a strong evidence that a better approximation algorithm is possible using the configuration LP and it allows the optimum to be estimated within a factor better than $1.75$. A particularly interesting aspect of our techniques is the way we handle small edges in the local search. We manage to exploit the configuration constraints enforced on small edges in the LP. This may be of interest to other problems such as Restricted Assignment as well.
Etude analytique des performances des systèmes radio-mobiles en présence d'évanouissements et d'effet de masque

Cette these a pour but l'analyse des performances d'une communication radio en presence d'evanouissements et d'eﬀet de masque. Le masquage, du aux obstacles entre l'emetteur et le recepteur, fait varier la probabilite d'erreur moyenne ("Symbole Error Probability" SEP). L'etude de la probabilite de coupure symbole (SEO "Symbol error Outage") deﬁnie comme la probabilite que le SEP moyen excede une valeur seuil est donc plus pertinent. La diﬃculte de son etude reside dans le fait qu'une inversion du SEP moyen par rapport au SNR (Signal to Noise Ratio) est necessaire. Par la methode de Laplace nous donnons des approximations precises a tout SNR du SEP dans un canal de Nakagami-m et Rice dans le cas mono-antenne. Nous montrons ensuite que ces approximations sont inversibles par rapport au SNR et permettent d'exprimer analytiquement le SEO en fonction du SEP cible. Nous integrons ensuite le codage canal et derivons des expressions analytiques de la probabilite de coupure paquet pour un codage bloc puis un codage convolutif a entree decidee. Nous etendons l'etude aux systemes MIMO a codage bloc orthogonaux puis a multiplexage spatial ou des formes exactes du SEO sont derivees. Nous considerons le cas ou des interferents sont presents. Nous derivons une approximation precise et inversible de la probabilite d'erreur lorsque les signaux se propagent a travers un canal a evanouissements rapides de Rayleigh. Enﬁn parce que la prise en compte de l'interference est un moyen avere d'augmenter la capacite des reseaux, nous etudions les performances de la detection multiutilisateurs a maximum de vraisemblance (MUD-MLSE), dans un contexte WLAN a canaux recouvrant.
Die „Eurodiet“ – eine konsequente Ergänzung zu ambulanter, ärztlicher Ernährungsberatung

Nicht nur in Fachkreisen ist bekannt, dass durch Gewichtsreduktion und vermehrte körperliche Bewegung dem metabolischen Syndrom und seinen Folgeerkrankungen vorgebeugt werden kann. Für kaum ein anderes Krankheitsbild ist die Evidenz derart eindeutig. Dass wir gegen die Adipositas-Epidemie etwas tun müssen ist unstrittig (7). Was wir tun sollen, darüber streiten die Fachwelt und diverse Anbieter aus Pharma-, Ernährungs- und Fitnessindustrie, aber auch die Krankenkassen, Fachverbände und selbsternannte Spezialisten. Zusammenfassung Vorgestellt wird ein individuelles, ambulantes Ernährungsberatungskonzept für die Hausarztpraxis. Die Möglichkeiten der ärztlichen und verhaltenstherapeutischen Beratung zu Ernährungsumstellung, Gewichtsreduktion und vermehrter körperlicher Bewegung werden erweitert durch das Angebot der “Eurodiet”, einer hochproteinreichen, ketogenen, sehr niedrigkalorischen Formula-Diät (VLCD), deren Anwendung ärztlich betreut wird. Die Diät wird in vier Phasen mit flexibler Reihenfolge angewandt und geht fließend über in eine proteinreiche Mittelmeerkost. Die Langzeiterfolge unter hausärztlicher Betreuung sind beachtlich.
Advances in hearing prosthetics

This text analyses several topics connected with he aring test methods and hearing prosthetics for patients with hearing impairments o r hearing loss. The hearing is one of the senses which plays a crucial part in human's cognition of the surrounding world and spatial orientation. Proper functioning o f the hearing organ is a foundation of communication between people as well as the deve lopment of civil society. A hearing impairment or hearing loss disrupts socia l rel tionships between people, it entails developmental disorders in children, and causes learning difficulties. Methods of diagnosing patients and hearing prosthetics are very complex topics and are investigated by interdisciplinary research teams. T he development of these fields of medicine and technology contributes to improving the quality of life for people with hearing impairment or deafness. This paper pre sents ways and means of improving or compensating for hearing losses with the us of hearing aids. Nowadays, hearing impairments and hearing losses concern even young people. One of the reasons for the deterioration of hearing is the ubiqui tous noise in the modern world. Moreover, this text discusses the construction of h earing aids, with a particular emphasis placed on modern technological solutions. It i highlighted that hearing aids are currently available for the general public.
Highly linear balanced power amplifiers for carrier aggregation

This article presents a highly linear balanced power amplifier with miniaturized quadrature hybrid coupler for carrier aggregation (CA). The miniaturized quadrature coupler is designed using a novel U‐shaped transmission line (USTL) concept to achieve good size reduction. The novel branch‐line coupler is used to design a wideband balanced PA. The performance of the balanced PA is compared to a single PA solution. The balanced PA shows better performance with improved matching properties and better electrical stability. There was an increase in saturated maximum output power (Pout) from 8 dBm for the individual PA to 13.41 dBm for the balanced with a power‐aided efficiency (PAE) of 43.92%. The highly linear balanced PA achieves a 14 dB ACPR reduction and also improves ACPR by 12 dB for noncontiguous and 9 dB for contiguous carrier aggregation.
CURATIVE POWERS OF BACH REMEDIES: A REVIEW

Human mind is a complex network of neurons working through the electromagnetic impulses and radiations. These are subtle energies whose balance affects the overall well-being of the person. Plants and their parts contain various bioactive compounds having various effects on physical, emotional and psychological effects on human body. Flower essences are subtle extracts having profound effect on emotional well-being, soul development and mind-body health. Floral remedies including Bach Remedies very popular in the West as a part of complementary medicine are thought to be effective in psychosomatic and related ailments. This review covers the healing powers of Bach and other flower remedies, described by Dr. Bach, The Mother of Sri Aurobindo Society and others, their classification, preparation, clinical trials and their usefulness in healing Thy self.
Algebraic approach to promise constraint satisfaction

The complexity and approximability of the constraint satisfaction problem (CSP) has been actively studied over the last 20 years. A new version of the CSP, the promise CSP (PCSP) has recently been proposed, motivated by open questions about the approximability of variants of satisfiability and graph colouring. The PCSP significantly extends the standard decision CSP. The complexity of CSPs with a fixed constraint language on a finite domain has recently been fully classified, greatly guided by the algebraic approach, which uses polymorphisms — high-dimensional symmetries of solution spaces — to analyse the complexity of problems. The corresponding classification for PCSPs is wide open and includes some long-standing open questions, such as the complexity of approximate graph colouring, as special cases. The basic algebraic approach to PCSP was initiated by Brakensiek and Guruswami, and in this paper we significantly extend it and lift it from concrete properties of polymorphisms to their abstract properties. We introduce a new class of problems that can be viewed as algebraic versions of the (Gap) Label Cover problem, and show that every PCSP with a fixed constraint language is equivalent to a problem of this form. This allows us to identify a ”measure of symmetry” that is well suited for comparing and relating the complexity of different PCSPs via the algebraic approach. We demonstrate how our theory can be applied by improving the state-of-the-art in approximate graph colouring: we show that, for any k≥ 3, it is NP-hard to find a (2k−1)-colouring of a given k-colourable graph.
ESTRESSE NO AMBIENTE OCUPACIONAL: FUNDAMENTOS SOBRE CAUSAS E CONSEQUÊNCIAS PARA SÍNDROMES METABÓLICAS

Worker stress has become a relevant factor in the occupational environment. In this context, the present research seeks to identify the influence of stress at the work environment. This is a systematic review, based on SciELO, LILACS, PubMed, Embase and the Cochrane library, between 1990 and 2016. The descriptors “worker, stress, metabolism and production” were used, supported on Bibliometric techniques. We selected 31 scientific studies on the subjects corresponding to the descriptors. This review found that the theme corresponding to the association between obesity and stress was shown to be reduced in the literature. In this way, we suggest researches with methodological analyzes of a more specific laboratory character in the attempt to verify this relation and to allow a better quality of life to the worker. The socioeconomic factor is relevant in the outcomes and the presence of stress and obesity was recurrent in the working environment of tension and too much physical and intellectual effort with the possibility of chances and / or indicators for metabolic syndromes.
Inertial Sensor Angular Velocities Reflect Dynamic Knee Loading during Single Limb Loading in Individuals Following Anterior Cruciate Ligament Reconstruction

Difficulty quantifying knee loading deficits clinically in individuals following anterior cruciate ligament reconstruction (ACLr) may underlie their persistence. Expense associated with quantifying knee moments (KMom) and power (KPow) with gold standard techniques precludes their use in the clinic. As segment and joint kinematics are used to calculate moments and power, it is possible that more accessible inertial sensor technology can be used to identify knee loading deficits. However, it is unknown if angular velocities measured with inertial sensors provide meaningful information regarding KMom/KPow during dynamic tasks post-ACLr. Twenty-one individuals 5.1 ± 1.5 months post-ACLr performed a single limb loading task, bilaterally. Data collected concurrently using a marker-based motion system and gyroscopes positioned lateral thighs/shanks. Intraclass correlation coefficients (ICC)(2,k) determined concurrent validity. To determine predictive ability of angular velocities for KMom/KPow, separate stepwise linear regressions performed using peak thigh, shank, and knee angular velocities extracted from gyroscopes. ICCs were greater than 0.947 (p < 0.001) for all variables. Thigh (r = 0.812 and r = 0.585; p < 0.001) and knee (r = 0.806 and r = 0.536; p < 0.001) angular velocities were strongly and moderately correlated to KPow and KMom, respectively. High ICCs indicated strong agreement between measurement systems. Thigh angular velocity (R2 = 0.66; p < 0.001) explained 66% of variance in KPow suggesting gyroscopes provide meaningful information regarding KPow. Less expensive inertial sensors may be helpful in identifying deficits clinically.
Dirichlet belief networks for topic structure learning

Recently, considerable research effort has been devoted to developing deep architectures for topic models to learn topic structures. Although several deep models have been proposed to learn better topic proportions of documents, how to leverage the benefits of deep structures for learning word distributions of topics has not yet been rigorously studied. Here we propose a new multi-layer generative process on word distributions of topics, where each layer consists of a set of topics and each topic is drawn from a mixture of the topics of the layer above. As the topics in all layers can be directly interpreted by words, the proposed model is able to discover interpretable topic hierarchies. As a self-contained module, our model can be flexibly adapted to different kinds of topic models to improve their modelling accuracy and interpretability. Extensive experiments on text corpora demonstrate the advantages of the proposed model.
Patients With Ischemic Core ≥70 ml Within 6 h of Symptom Onset May Still Benefit From Endovascular Treatment

Background: Large core is associated with poor outcome in acute ischemic stroke (AIS) patients. It is unclear whether endovascular treatment (EVT) could bring benefits to patients with core volume ≥70 ml before treatment. We aimed to compare the impact of EVT with intravenous thrombolysis (IVT) on the outcome in patients with core volume ≥70 ml. Methods: We included consecutive anterior circulation AIS patients who underwent MR or CT perfusion within 6 h post stroke onset, which revealed a core ≥70 ml before reperfusion therapy. Good outcome was defined by modified Rankin Scale of 0 to 2 at 90-day. Reperfusion was defined as a reduction in hypoperfusion volume of ≥70% between baseline and 24 h. Results: One hundred four patients were included. Among them, 76 received IVT only, and 28 received EVT. After adjusting for age, NIHSS score, baseline core volume and onset to imaging time, patients in EVT group were more likely to achieve good outcome compared to IVT patients (OR, 3.875; 95% Cl 1.068–14.055, p = 0.039). More patients in EVT group achieved recanalization (84.0 vs. 58.5%, p = 0.027) and reperfusion (66.7 vs. 33.3%, p = 0.010) than in IVT group. Reperfusion also independently predicted good outcome (OR, 7.718; 95% Cl 1.713-34.772, p = 0.008). All patients with good outcome achieved recanalization at 24 h. Conclusions: Our data indicated that patients with core volume ≥70 ml might still benefit from EVT, which was related to its high reperfusion rate.