Miracle-dz/UniFAR-FTUs huggingface dataset:
Multiple attribute group decision making methods based on intuitionistic fuzzy frank power aggregation operators

On the basis of Frank operators, the operational rules of intuitionistic fuzzy numbers are redefined, then the intuition- istic fuzzy Frank power average operator (IFFPA), intuitionistic fuzzy Frank power weighted average operator (IFFPWA) and intuitionistic fuzzy Frank power ordered weighted average operator (IFFPOWA) are proposed by combining Frank operations and power aggregation operators. At the same time, some desirable properties of these operators, such as idempotency, commutativity and boundedness, are studied, and some special cases are analyzed. Furthermore, with respect to multiple attribute group decision making (MAGDM) problems in which attribute values take the form of the intuitionistic fuzzy numbers, two group decision making methods based on IFFPWA and IFFPOWA operators are developed. Finally, an illustrative example is given to verify the proposed methods and to demonstrate their practicality and effectiveness.
Intersecting straight line segments with disks: complexity and approximation

Computational complexity and approximability are studied for a problem of intersecting a set of straight line segments with the smallest cardinality set of disks of ﬁxed radii r > 0 where the set of segments forms a straight line drawing G = ( V, E ) of a planar graph without edge crossings. Similar problems arise e
Reconsidering Detached Concern: The Case of Intensive-Care Nurses

The concept of detached concern, as proposed by Renée Fox in Experiment Perilous (1959), is often used in the literature today in a way she did not intend. Rather than viewing detachment and concern as dualities, scholars frequently conceive of them as dichotomous, emphasizing detachment over concern. We reconsider detached concern here through the stories 37 intensive-care nurses told about their most memorable patients. While many described efforts to keep emotionally distant from patients, they also expressed concern for patients they felt connected to, especially those who were a first for them, who were long-term primary patients, who surprised them, or who died. The care nurses provide for these patients is shaped sociologically by their training and institutional contexts and is not an aberration or indicative of their losing control of their feelings. Instead, it is evidence of the dual nature of detached concern and of the importance of viewing the concept as describing more than emotional detachment.
Adaptive reservation in WLAN networks under smooth random mobility model

This papers presents a novel technique to predict the number of WLAN cells visited by a mobile host during its call holding time. A two-dimensional wireless mobility model called Smooth Random Mobility Model (SRMM) has been considered, because it makes the movement of users smoother and more realistic than well-known in literature random mobility models. A prediction technique based both on the analysis of Cell Stay Time and on the direction probabilities of hand-in and hand-out events of mobile nodes from wireless cells is outlined, as a method for QoS guarantees, lower bandwidth wastage and higher system utilisation. An integrated architecture able to make active and passive reservations has been applied as possible application of the proposed approach. Simulation results have been carried out and an interesting bandwidth management usage has been observed.
Ethnicity and Scholastic Achievement

Scores on tests in 8 areas of scholastic achievement were “predicted” by multiple regression from 7 nonscholastic tests of ability, a personality inventory, and items of personal background data in some six thousand white, Negro, and Mexican-American California school children in Grades 1 to 8. Averaged over Grades, the multiple correlation (R) between the predictor variables and achievement scores ranged from . 60 to . 80 for various school subjects. Ethnicity made no significant contribution to the multiple R independently of the several predictor variables.
A system for efficient rendering of human skin

Figure 1: We project multi-layer diffusion profiles onto a sumof-Gaussians basis to enable realistic rendering of human skin at 30 frames per second on a modern GPU. From left to right: Albedo (1st) and irradiance (2nd) combine to give subsurface irradiance which is then convolved with each Gaussian basis profile (3rd through 7th) and combined in a final render pass with specular (8th) to produce the final image (9th). Convolutions are performed in off-screen 2D textures but shown here mapped onto the face.
Data compression of EEG signals for artificial neural network classification

Brain – Computer interface (BCI) systems require intensive signal processing in order to form control signals for electronic devices. The majority of BCI systems work by reading and interpreting cortically evoked electro-potentials across the scalp via an electro-encephalogram (EEG). Feature extraction and classification are the main tasks in EEG signal processing. In this paper, we propose method to compress EEG data using discrete cosine transform (DCT). DCT takes correlated input data and concentrates its energy in just first few transform coefficients. This method is used as feature extraction step and allows reducing data size without losing important information. For classification we are using feed forward artificial neural network. Experimental results show that our proposed method does not lose the important information. We conclude that the method can be successfully used for the feature extraction. DOI: http://dx.doi. org/10.5755/j01.itc. 42.3. 1986
A framework for identifying and understanding enterprise systems benefits

Purpose – Identifying the benefits arising from implementations of enterprise systems and realizing business value remains a significant challenge for both research and industry. This paper aims to consolidate previous work. It presents a framework for investigating enterprise systems benefits and business change, which addresses the identified limitations of previous research and provides a more detailed analysis of benefits and their contextual variation.Design/methodology/approach – Drawing on data gathered from 31 real‐world organizations (case studies) of differing size, maturity, and industry sector, the study adopts an iterative content analysis to empirically derive a comprehensive benefits framework.Findings – The content analysis provides a detailed classification of expectations and benefits, which is described in a four‐level framework. The four levels (areas) are further subdivided into aspects and criteria plus an attributed appraisal value. The resulting scheme for the “three‐level benefit .
Composition and Anti-Wood-Decay Fungal Activities of the Leaf Essential oil of Machilus philippinensis from Taiwan

The hydrodistilled leaf essential oil of Machilus philippinensis was analyzed to determine its composition and yield. Seventy compounds were identified, the main ones being β-caryophyllene (13.6%), α-pinene (12.0%), α-cadinol (7.4%), cis-ocimene (7.0%), spathulenol (5.6%), (E)-nerolidol (5.3%), tau-cadinol (4.8%) and β-pinene (4.5%). Monoterpene hydrocarbons (36.1%) and oxygenated sesquiterpenes (33.0%) were the predominant groups of compounds. The leaf oil exhibited excellent anti-wood-decay fungal activities.
An Evolutionarily Conserved Motif in the TAB1 C-terminal Region Is Necessary for Interaction with and Activation of TAK1 MAPKKK*

TAK1, a member of the MAPKKK family, is involved in the intracellular signaling pathways mediated by transforming growth factor β, interleukin 1, and Wnt. TAK1 kinase activity is specifically activated by the TAK1-binding protein TAB1. The C-terminal 68-amino acid sequence of TAB1 (TAB1-C68) is sufficient for TAK1 interaction and activation. Analysis of various truncated versions of TAB1-C68 defined a C-terminal 30-amino acid sequence (TAB1-C30) necessary for TAK1 binding and activation. NMR studies revealed that the TAB1-C30 region has a unique α-helical structure. We identified a conserved sequence motif, PYVDXA/TXF, in the C-terminal domain of mammalian TAB1, Xenopus TAB1, and itsCaenorhabditis elegans homolog TAP-1, suggesting that this motif constitutes a specific TAK1 docking site. Alanine substitution mutagenesis showed that TAB1 Phe-484, located in the conserved motif, is crucial for TAK1 binding and activation. The C. eleganshomolog of TAB1, TAP-1, was able to interact with and activate theC. elegans homolog of TAK1, MOM-4. However, the site in TAP-1 corresponding to Phe-484 of TAB1 is an alanine residue (Ala-364), and changing this residue to Phe abrogates the ability of TAP-1 to interact with and activate MOM-4. These results suggest that the Phe or Ala residue within the conserved motif of the TAB1-related proteins is important for interaction with and activation of specific TAK1 MAPKKK family members in vivo.
Construction analysis for inherent reliability evaluation of surface acoustic wave filters

Inherent reliability of Surface acoustic wave filters plays a key role for its application in the mobile communication systems. Construction analysis is an effective method for evaluating the inherent reliability of electronic components. This work provides a construction analysis process for the surface acoustic wave filters, which includes external encapsulation analysis, internal encapsulation analysis and chip-level analysis. The results show that oxidation occurs on the upper surface of the Al electrodes and leads to the formation of Al2O3. The break in the Al electrode stripe is observed.
Identification of Pavinane Alkaloids in the Genera Argemone and Eschscholzia by GC-MS

The genera Eschscholtzia and Argemone(Papaveraceae) represent a rich source of pavinane alkaloids, the identification of which in alkaloid extracts is generally problematic without standards. The alkaloid extracts of three Argemone and four Eschscholtzia species were analyzed using GC-MS. The alkaloids were identified based on comparison of their mass spectra with commercial libraries, with reported data in the literature and with spectra of reference compounds. A total of 23 alkaloids of six structural types (pavinane, protopine, benzylisoquinoline, benzophenanthridine, aporphine and protoberberine) were identified. The fragmentation pathway of pavinane alkaloids was used for their identification. O-Methylneocaryachine has been reported for the first time from a natural sources and the alkaloid pattern of Eschscholzia pulchella has been analyzed and described for the first time.
Using relevance feedback to reduce the semantic gap in content-based image retrieval of mammographic masses

This paper presents the use of relevance feedback (RFb) to reduce the semantic gap in content-based image retrieval (CBIR) of mammographic masses. Tests were conducted where the radiologists' classification of the lesions based on the BI-RADS categories were used with techniques of query-point movement to incorporate RFb. The measures of similarity of images used for CBIR were based upon Zernike moments. The performance of CBIR was measured in terms of precision and recall of retrieval. The results indicate improvement due to RFb of up to 41.6% in precision. In our experiments, the gain in the performance of CBIR with RFb was associated with the BI-RADS category of the query mammographic image, with large improvement in cases of lesions belonging to categories 4 and 5. The proposed method could find applications in computer-aided diagnosis (CAD) of breast cancer.
Experimental Shigella Infections. III. Sensitivity of Normal, Starved and Carbon Tetrachloride Treated Guinea Pigs to Endotoxin

Summary Pretreatment of Hartley strain guinea pigs either by subcutaneous injection with carbon tetrachloride or by 4 day period of starvation renders them more susceptible to intravenously administered endotoxin. The LD50 for normal animals is in excess of 1300 μg; for starved animals 52.8 μg and for carbon tetrachloride treated animals 4.2 μg. Distribution of Cr51 label of Cr51 tagged endotoxin in organs of normal animals which survive intravenous dose of 52 μg of endotoxin is the same as that in carbon tetrachloride treated animals which succumb following this challenge.
A sine cosine mutation based differential evolution algorithm for solving node location problem

Differential Evolution (DE) algorithm is known in evolutionary computation. However, DE with DE/best/1 mutation has some drawbacks such as premature convergence and local optimum. To address these drawbacks, we improve the DE/best/1 mutation operator and propose a sine cosine mutation based differential evolution algorithm, named SCDE. In the proposed method, a new sine cosine mutation operator inspired by sine cosine algorithm (SCA) is adopted to balance exploration and exploitation. In the experimental simulation, the proposed algorithm is compared with three state-of-the-art algorithms on the well-known benchmark test functions. The results of test functions and performance metrics show that the proposed algorithm is able to avoid local optima and converge towards the global optimum. In addition, the proposed algorithm is used to solve sensor node location in wireless sensor network. Results show that our algorithm is effective.
The emerging role of calmodulin regulation of RyR2 in controlling heart rhythm, the progression of heart failure and the antiarrhythmic action of dantrolene

Cardiac output and rhythm depend on the release and the take‐up of calcium from the sarcoplasmic reticulum (SR). Excessive diastolic calcium leak from the SR due to dysfunctional calcium release channels (RyR2) contributes to the formation of delayed after‐depolarizations, which underlie the fatal arrhythmias that occur in heart failure and inherited syndromes. Calmodulin (CaM) is a calcium‐binding protein that regulates target proteins and acts as a calcium sensor. CaM is comprised of two calcium‐binding EF‐hand domains and a flexible linker. CaM is an accessory protein that partially inhibits RyR2 channel activity. CaM is critical for normal cardiac function, and altered CaM binding and efficacy may contribute to defects in SR calcium release. The present paper reviews CaM binding to RyR2 and how it regulates RyR2 channel activity. It then goes on to review how mutations in the CaM amino acid sequence give rise to inherited syndromes such as Catecholaminergic Polymorphic Ventricular Tachychardia (CPVT) and long QT syndrome (LQTS). In addition, the role of reduced CaM binding to RyR2 that results from RyR2 phosphorylation or from oxidation of either RyR2 or CaM contributes to the progression of heart failure is reviewed. Finally, this manuscript reviews recent evidence that CaM binding to RyR2 is required for the inhibitory action of a pharmaceutical agent (dantrolene) on RyR2. Dantrolene is a clinically used muscle relaxant that has recently been found to exert antiarrhythmic effects against SR Ca2+ overload arrhythmias.
Measurements of Permittivity and Dielectric Loss Tangent of High Resistivity Float Zone Silicon at Microwave Frequencies

Real part of permittivity and the dielectric loss tangent of float zone high resistivity Silicon were measured at microwave frequencies at temperatures from 10 K up to 380 K employing dielectric resonator technique. The real part of permittivity proved to be frequency independent and the decrease in dielectric loss tangent versus frequency proved to be not entirely proportional to the inverse of frequency. At temperatures below 25 K where all free carriers are frozen-out loss tangents values the order of 10-4 were measured.
Effect of estrogen treatment on plasma oxytocin and vasopressin in ovariectomized rats.

Effects of estrogen treatment (estradiol benzoate 20μg per day for 2days) on plasma concentration of oxytocin and vasopressin were studied in ovariectomized female rats under urethane-anesthesia (1.2g/kg). Plasma oxytocin was measured by bioassay, while plasma vasopressin was determined by both bioassay and radioimmunoassay. Plasma oxytocin levels (46.2-232.2μU /ml) in the jugular blood of estrogentreated rats were found to be significantly (p<0.05) higher than those (non-detectable level to130.0μU/ml) of the ovariectomized control rats. The mean plasma vasopressin levels determined by bioassay were 172±66 (mean±SEM)%mu;U/ml in control rats and 176±32μU/ml in estrogen-treated rats. The mean concentrations of immunoreactive plasma vasopressin were60.1±19. 6μU/ml in the control and75.5±26. 8μU/ml in estrogen treated rats. Thus no significant change in plasma vasopressin due to the estrogen treatment was found, whatever method was employed to determine its concentrations.Anterior or posterior hypothalamic deafferentations were made in estrogen-treated ovariectomized rats. The facilitatory effect of estrogen on oxytocin release was not found in the rats with anterior deafferentation. The plasma oxytocin level in the estrogentreated rats with the anterior deafferentation was significantly (p<0.05) lower than that in the estrogen-treated rats without the hypothalamic deafferentation. On the other hand, the plasma oxytocin level in the estrogen-treated rats with posterior deafferentation did not show any significant difference from either that of ovariectomized control rats or that of estrogen-treated ovariectomized rats with intact brain.The present data indicate that estrogen stimulates oxytocin release in the female rat and that such an action of estrogen is exerted mainly by activating the anterior neural input to the neurosecretory cells in the hypothalamo-neurohypophysial system. Whether or not estrogen gives influence on the posterior neural input to the neurosecretory cells is equivocal in the present experiment.An additional experiment was made to determine the effect of urethane on plasma vasopressin. Urethane-anesthetized rats showed a significantly (p<0.01) higher plasma vasopressin level than conscious or pentobarbitone-anesthetized rats.
TensorCast: Forecasting with Context Using Coupled Tensors (Best Paper Award)

Given an heterogeneous social network, can we forecast its future? Can we predict who will start using a given hashtag on twitter? Can we leverage side information, such as who retweets or follows whom, to improve our membership forecasts? We present TensorCast, a novel method that forecasts time-evolving networks more accurately than current state of the art methods by incorporating multiple data sources in coupled tensors. TensorCast is (a) scalable, being linearithmic on the number of connections; (b) effective, achieving over 20% improved precision on top-1000 forecasts of community members; (c) general, being applicable to data sources with different structure. We run our method on multiple real-world networks, including DBLP and a Twitter temporal network with over 310 million non-zeros, where we predict the evolution of the activity of the use of political hashtags.
C3 Toxin Activates the Stress Signaling Pathways, JNK and p38, but Antagonizes the Activation of AP-1 in Rat-1 Cells*

Lysophosphatidic acid (LPA) stimulates the c-Fos serum response element (SRE) by activating two distinct signal pathways regulated by the small GTPases, Ras and RhoA. Ras activates the ERK cascade leading to phosphorylation of the transcription factors Elk-1 and Sap1a at the Ets/TCF site. RhoA regulates an undefined pathway required for the activation of the SRF/CArG site. Here we have examined the role of the Ras and RhoA pathways in activation of the SRE and c-Fos expression in Rat-1 cells. Pertussis toxin and PD98059 strongly inhibited LPA-stimulated c-Fos expression and activation of a SRE:Luc reporter. C3 toxin completely inhibited RhoA function, partially inhibited SRE:Luc activity, but had no effect on LPA-stimulated c-Fos expression. Thus, in a physiological context the Ras-Raf-MEK-ERK pathway, but not RhoA, is required for LPA-stimulated c-Fos expression in Rat-1 cells. C3 toxin stimulated the stress-activated protein kinases JNK and p38 and potentiated c-Jun expression and phosphorylation; these properties were shared by another cellular stress agonist the protein kinase C inhibitor Ro-31-8220. However, C3 toxin alone or in combination with growth factors did not stimulate AP-1:Luc activity and actually antagonized the synergistic activation of AP-1:Luc observed in response to co-stimulation with growth factors and Ro-31-8220. These data indicate that C3 toxin is a cellular stress which antagonizes activation of AP-1 at a point downstream of stress-activated kinase activation or immediate-early gene induction.
Immunotoxins containing saporin 6 and monoclonal antibodies recognizing plasma cell‐associated antigens: Effects on target cells and on normal myeloid precursors (CFU‐GM)

Monoclonal antibodies 8A and 62B1, recognizing plasma cell‐associated antigens, were covalently linked to saporin 6, a ribosome‐inactivating protein similar to the A‐chain of ricin. Both immunotoxins were tested on target human cell lines U266 and Raji, on non‐target K562 cell line and on myeloid CFU‐GM progenitors. The cloning efficiency and viability of target cells were strongly reduced by 8A‐saporin 6 and 62B1‐saporin 6 immunotoxins, with an ID50 up to 200000‐fold lower than free saporin 6, whilst the K562 non‐target cell line was unaffected. Normal human myeloid precursors (CFU‐GM) were inhibited by immunotoxins only to a limited extent. An application of this model for autologous bone marrow transplantation in multiple myeloma patients is proposed. Since no eradication of cloning target cells was achieved by a single immunotoxin, mixtures made with different antibodies could help to reach this goal.
Factors Affecting the Tuberculosis Risk in Patients Receiving Anti-Tumor Necrosis Factor-α Treatment

Background: Tumor necrosis factor (TNF)-α inhibitors are known to increase the risk of tuberculosis (TB). Objectives: To examine the factors associated with an increased risk of TB in patients receiving anti-TNF-α treatment (aTNF-α-T). Method: Of 3,094 patients who received aTNF-α-T between 2003 and 2013, a total of 1,964 subjects with a follow-up time longer than 6 months were identified and included in this retrospective analysis. Potential risk factors for the development of TB in patients receiving aTNF-α-T were evaluated. Results: Of the 1,964 patients, 1,009 (51%) were male and 955 (49%) were female, with a mean age of 39.7 ± 13.9 years. The primary conditions requiring aTNF-α-T included ankylosing spondylitis (n = 875), rheumatoid arthritis (n = 711), Behçet's disease (n = 83), and others (n = 295). Sixteen patients [8 (50%) males and 8 (50%) females; 5 (31.2%) with pulmonary TB and 11 (68.8%) with extrapulmonary TB] developed TB, with a corresponding TB incidence of 466/100,000. No significant associations were found between age, gender, smoking history, pack-years of smoking, isoniazid (INH) chemoprophylaxis, type of anti-TNF-α agent, use of other immunosuppressive drugs, and the risk of TB (p > 0.05). Multivariate logistic regression analysis showed a significantly higher risk of TB in patients diagnosed with Behçet's disease, and a significantly lower risk of TB in patients with a tuberculin skin test wheal ≥10 mm in diameter (p < 0.05). Conclusion: aTNF-α-T is associated with an increased risk of pulmonary or extrapulmonary TB, even when follow-up protocols and INH chemoprophylaxis are implemented, and TB often develops in the later stages of treatment. The risk of TB was higher in patients with Behçet's disease and lower in patients who had a strong tuberculin skin test reaction.