Miracle-dz/UniFAR-FTUs huggingface dataset:
The Researching the relationship between operational efficiency with profitability of telecommunication technology joint-stock companies.

Operational efficiency (OE) and profitability are always the first priorities of any enterprise. Therefore, studying the relationship between OE and profitability needs to be taken comprehensively and continuously in order to find out solutions of business effectiveness increase. This paper focuses on the relationship between OE and profitability of the telecommunication technology (TT) joint-stock companies (JSCs) listed on the Ho Chi Minh Stock Exchange (HOSE) with answers for the above-mentioned issues. Keywords JSCs, operational efficiency, profitability, telecommunication technology References [1] Beal V. (without published year), Operational Efficiency, cited 30/07/2016 from http://www.webopedia. com/TERM/O/operational_efficiency. html>. [2] Burrows M. (without published year), Operational Efficiency - It’s not just about Cost Cutting, cited 30/07/2016 from http://www.bsmreview. com/oppseff.shtml>. [3] Hartman D. (without published year), How to Calculate the Maximization of Operational Efficiency, cited 30/07/2016 from http://smallbusiness.chron. com/calculate-maximization-operational-efficiency-35448.html>. [4] Kokemuller N. (without published year), What Is the Meaning of Operational Efficiency? , cited 30/07/2016 from http://smallbusiness.chron. com/meaning-operational-efficiency-67982.html>. [5] Kokemuller N. (without published year), Operational Effectiveness Vs. Strategic Positioning, cited 30/07/2016 from http://www.ehow. com/info_8447934_operational-effectiveness-vs-strategic-positioning.html>. [6] Varadan S. (without published year). What Is the Meaning of Operational Efficiency? , cited 30/07/2016 from http://www.ehow. com/about_6495198_meaning-operational-efficiency_. html>. [7] ‘Operational Efficiency’ (2016), Wikipedia, cited 30/07/2016 from https://en.wikipedia. org/wiki/Operational_efficiency. [8] Nguyen Van Cong (2009), Business Operation Analysis Textbook, National Economics Publisher, Hanoi (Nguyễn Văn Cong, 2009, Giao trinh Phân tich hoạt động kinh doanh, Trường Đại học Kinh tế Quốc dân, Ha Nội). [9] Gibson C. H. (2001), Financial Reporting Analysis: Using Financial Accounting Information, 8th ed., South-Western College Publishing, Thomson Learning. [10] Harward & Upto, (1961), Introduction to Business Finance, Mc Graw Hill, New York. [11] Patel S. B. P (2015), ‘Effects of Accounting Information System on Organizational Profitability’, International Journal of Research and Analytical Reviews, vol.2, iss. 1, pp.72-77. [12] Hofstrand D. (without published year). Understanding Profitability, cited 30/07/2016 from https://www.extension. iastate.edu/agdm/wholefarm/html/c3-24.html>. [13] Dang Ngoc Duc and Tran Tho Dat (2016), Monetary policy in period of 2011-2015 and its impacts on the economy, cited 30/07/2016 from http://kinhtevadubao.vn/chi-tiet/101-5229-chinh-sach-tien-te-giai-doan-2011-2015-va-nhung-tac-dong-toi-nen-kinh-te.html>. (Đặng Ngọc Đức va Trần Thọ Đạt, 2016, Chinh sach tiền tệ trong giai đoạn 2011 – 2015 va va tac động của no đến nền kinh tế).
ANovel Compound , NK 150460 , Exhibits Selective Antitumor Activity against Breast Cancer Cell Lines through Activation of Aryl Hydrocarbon Receptor

Antiestrogen agents are commonly used to treat patients with estrogen receptor (ER)–positive breast cancer. Tamoxifen has been the mainstay of endocrine treatment for patients with early and advanced breast cancer for many years. Following tamoxifen treatment failure, however, there are still limited options for subsequent hormonal therapy.Wediscovered anovel compound, NK150460, that inhibits 17b-estradiol (E2)–dependent transcription without affecting binding of E2 to ER. Against our expectations, NK150460 inhibited growth of not only most ER-positive, but also some ER-negative breast cancer cell lines, while never inhibiting growth of non–breast cancer cell lines. Cell-based screening using a random shRNA library, identified aryl hydrocarbon receptor nuclear translocator (ARNT) as a key gene involved in NK150460's antitumor mechanism. siRNAs against not only ARNT but also its counterpart aryl hydrocarbon receptor (AhR) and their target protein, CYP1A1, dramatically abrogated NK150460's growth-inhibitory activity. This suggests that the molecular cascade of AhR/ARNT plays an essential role in NK150460's antitumor mechanism. Expression of ERa was decreased by NK150460 treatment, and this was inhibited by an AhR antagonist. Unlike two other AhR agonists now undergoing clinical developmental stage, NK150460 did not induce histone H2AX phosphorylation or p53 expression, suggesting that it did not induce a DNA damage response in treated cells. Cell lines expressing epithelial markers were more sensitive to NK150460 than mesenchymal marker-expressing cells. These data indicate that NK150460 is a novel AhR agonist with selective antitumor activity against breast cancer cell lines, and its features differ from those of the other two AhR agonists. Mol Cancer Ther; 14(2); 343–54.
A Homozygous Mutation in MSH6 Causes Turcot Syndrome

Heterozygous mutations in one of the DNA mismatch repair genes cause hereditary nonpolyposis colorectal cancer (MIM114500). Turcot syndrome (MIM276300) has been described as the association of central nervous system malignant tumors and familial colorectal cancer and has been reported to be both a dominant and recessive disorder. Homozygous and compound heterozygous mutations in APC, MLH1, MSH2, and PMS2 genes have been reported in five families. Here we describe a nonconsanguineous Pakistani family, including a son with lymphoma and colorectal cancer diagnosed at ages 5 and 8, respectively, and an 8-year-old daughter with glioblastoma multiforme. Both children had features of neurofibromatosis type 1 including atypical café au lait spots and axillary freckling without a family history consistent with neurofibromatosis type 1, familial adenomatous polyposis, or hereditary nonpolyposis colorectal cancer. Mutational analysis was done for MLH1, MSH2, and MSH6 using denaturing high-performance liquid chromatography and sequencing of a blood sample from the daughter. A novel homozygous single base insertion mutation was identified (3634insT) resulting in a premature stop at codon 1,223 in exon 7 of the MSH6 gene. Both parents were found to be heterozygous for the 3634insT mutation. Microsatellite instability testing showed instability in the glioblastoma sample. We report here the first identification of a homozygous mutation in MSH6 in a family with childhood-onset brain tumor, lymphoma, colorectal cancer, and neurofibromatosis type 1 phenotype. Our findings support a role for MSH6 in Turcot syndrome and are consistent with an autosomal recessive mode of inheritance.
Molecular cloning and characterization of high-affinity carnitine transporter from rat intestine.

Carnitine is an essential component for mitochondrial beta-oxidation of fatty acid. Using the degenerate primers designed for organic anion transporters and an organic cation transporter, we isolated a novel cDNA encoding a carnitine transporter (CT1) from rat intestine. CT1 encodes a 557-amino-acid protein with 12 putative membrane-spanning domains. When expressed in Xenopus oocytes, CT1 mediated a high-affinity transport of L-carnitine (Km = 25 microM). The replacement of extracellular sodium with Li reduced CT1-mediated L-carnitine uptake to 19.8%. CT1 did not transport typical substrates for either organic anion or organic cation transporters, such as p-aminohippurate and tetraethylammonium. Octanoylcarnitine, acetylcarnitine, and gamma-butyrobetaine showed potent inhibitory effects on CT1-mediated L-carnitine uptake; betaine and d-carnitine showed moderate inhibition. CT1 mRNA was strongly expressed in the testis, colon, kidney, and liver and weakly in the skeletal muscle, placenta, small intestine, and brain. No CT1 expression was detected in the heart, spleen, or lung. The present study provides the molecular basis of carnitine transport in the body.
Liver stiffness‐based model for prediction of hepatocellular carcinoma in chronic hepatitis B virus infection: comparison with histological fibrosis

Liver stiffness (LS) value using transient elastography is a reliable, non‐invasive tool for assessing liver fibrosis. LS‐based prediction model, LSPS (=LS value × spleen diameter/platelet count) is well correlated with the risk of developing portal hypertension‐related cirrhotic complications. Here, we assessed the prognostic performance of LSPS in predicting the development of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB).
MudPad: tactile feedback for touch surfaces

MudPad is a system enriching touch surfaces with localized active haptic feedback. A soft and flexible overlay containing magnetorheological fluid is actuated by an array of electromagnets to create a variety of tactile sensations. As each magnet can be controlled individually, we are able to produce feedback in realtime locally at arbitrary points of interaction.
An economic analysis of fluid milk resale trade and price regulations in the thirteen north central states

3. When a map, drawing or chart, etc., is part of the material being photo­ graphed the photographer has followed a definite method in “sectioning” the material. It is customary to begin filming at the upper left hand corner of a large sheet and to continue from left to right in equal sections with small overlaps. If necessary, sectioning is continued again—beginning below the first row and continuing on until complete.
IMPACT OF MARKETING AND R&D EXPENDITURES ON FINANCIAL PERFORMANCE: A RESEARCH IN MANUFACTURING INDUSTRY

Purpose- In this research it is aimed to investigate the impact of marketing and research and development (R&D) expenditures of companies on their financial performance in manufacturing industry. Methodology- Data of 41 manufacturing companies listed on Borsa Istanbul (BIST) was gathered for the period of 2009-2015 from their financial statements. Since the data set is a panel data, methods of panel regression analysis have been performed. Findings- As a result of the analysis, impact of marketing and R&D expenditures on firms’ performance differentiate according to financial performance measures and it is founded that they have no effect on some financial performance indicators. Conclusion- Test results imply that marketing and R&D expenditures have positive contribution to manufacturing companies’ some of the financial performance indicators. However, manufacturing companies cannot use marketing and R&D budgets in an effective and efficient way. Manufacturing companies are not able to manage marketing and R&D activities successfully.
Crystal structure of 2-benzylamino-4-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine-3-carbonitrile

The title compound comprises a 2-aminopyridine ring fused with a cycloheptane ring, which adopts a chair conformation. In the crystal, molecules are linked via pairs of N—H⋯Nnitrile hydrogen bonds, forming inversion dimers which enclose (14) ring motifs
The availability of management accounting information and its usefulness to managers in the manufacturing sector / Noraizah Abu Bakar

This study reports on the usefulness of MAIS and the availability of information to the operation managers in the manufacturing sectors. The study will categorize the information into four dimensions that are scope, timeliness, aggregation and integration. It is adopted from an earlier research carried out by Chenhall and Morris. Survey for the study has been conducted in the state of Johore involving three regions namely Segamat, Tangkak and Muar. The relationship between the availability of information to managers and how they make use of such information is very important for decision-making process especially for those in managerial and financial levels. The results for the study indicate that managers perceived all four dimensions information to be useful to them. On the contrary, the study indicates that the availability of information is not considered as an important factor in helping them to make better decisions. The finding further indicates that there is no significant relationship between the availability of information and how managers make use of them.
International Trade at the Speed of Light: Building an Electronic Trading Infrastructure in Denmark, Finland and Hong Kong

In this paper, we analyze the creation of electronic trading infrastructures using Electronic Data Interchange (EDI) standards and associated technologies. We compare the evolution of such infrastructures in Denmark, Finland, and Hong Kong. We analyze attempts to build trading infrastructures in these three countries by examining eight initiatives. We probe how these initiatives support the building efforts by locating the eight initiatives into a two dimensional framework, which distinguishes between the strategic intent of the initiative and the type of initiator. In each case, we examine the dynamics of each initiative and its success. Our analysis shows that the building of trading infrastructures can take place through multiple paths—in this study called patterns—and it can be “pulled” or “pushed” by multiple forces. As a result, we can draw conclusions about how each pattern can help in building the infrastructure. The analysis demonstrates that the trading infrastructure in Hong Kong
WYSIWYG—Seeing is Believing: Consumer Responses to Levels of Design Newness, Product Innovativeness, and the Role of Country-of-Origin

ABSTRACT There is a dearth of new product design research that investigates the impact of varying levels of design newness coupled with technical newness on consumer evaluations for incremental and radical innovations across utilitarian and hedonic product categories through the lens of country-of-origin (COO). In today's world, innovation may originate from both developed and emerging economies. Our research investigates consumer responses when incrementally new and/or radically new products come from developed as well as developing countries. Through four experimental studies, we found that consumers preferred high level of design newness in incrementally innovative utilitarian product category and low level of design newness in radically innovative utilitarian product category when products originate from developed countries (developed COO situation). High level of design newness was preferred for both incrementally new and really (radically) new utilitarian products originating from developing countries (emerging COO situation). In contrast, consumers preferred high level of design newness in both incrementally and radically innovative hedonic product categories during developed COO situation; and consumers preferred high level of design newness for incrementally new hedonic products while avoiding radically new hedonic products completely during emerging COO situation. The results have important implications for researchers and managers in developing incremental and radical innovations by understanding differential performance effects of levels of design and technical newness with respect to developed versus emerging COO situations and consumer purchase intentions.
Is Insomnia Associated With Cognitive Impairments in Breast Cancer Patients?

Insomnia and cognitive impairment are both highly prevalent in breast cancer patients. This study, conducted among women treated for non-metastatic breast cancer, aimed at assessing the relationship between insomnia and cognitive functioning, measured objectively and subjectively, and evaluating the moderating role of age, educational level and intellectual potential. Sixty-three women completed a neuropsychological battery, self-report scales of cognitive functioning, 2 weeks of a daily sleep diary, and a demographic and medical questionnaire. Significant differences between women with insomnia and good sleepers were found on verbal episodic memory and executive functioning, assessed objectively, and some aspects of subjective cognitive functioning. Moreover, older age and a higher education were associated with more severe cognitive impairments related to insomnia.
Evaluation of Jejunal Function in Wolman's Disease

Findings in a 1-month-old male infant with Wolman's disease, a rare autosomal defect characterized by intractable diarrhea and severe malabsorption, are described. Investigations in this case focused on the digestive and absorptive functions of the jejunum using histological, biochemical, and electrophysiological methods. The intestinal villi were found to be distorted and club-shaped as a result of the infiltration of foam cells into the lamina propria of the mucosa. The microvilli of the epithelial cells were found on electron microscopy to be markedly shortened and irregular, and had a severe impairment of disaccharidase activity. Documentation of the loss of the sugar- and amino acid-evoked potential differences in the jejunum confirmed the severity of intestinal malabsorption. These observations indicate that the intestinal damage in Wolman's disease is so severe as virtually to exclude the absorption of any form of enteral nutrition. Despite the administration of i.v. hyperalimentation, the infant died of hepatic failure at the age of 6 months.
Diagnosis of depth of invasion for early colorectal cancer using magnifying colonoscopy

Background and Aims: Early colorectal cancer (CRC) with submucosal deep (s.m.‐d.) invasion should not be treated with endoscopic mucosal resection due to the higher incidence of lymph‐node metastasis. It is, therefore, clinically important to accurately diagnose s.m. ‐d. lesions before treatment.
Smoking and abdominal obesity: risk factors for venous thromboembolism among middle-aged men: "the study of men born in 1913".

BACKGROUND Risk factors for deep vein thrombosis and pulmonary embolism are mostly derived from case-control studies of hospitalized patients, and there are few long-term population-based studies. OBJECTIVE To study the long-term risk factors for deep vein thrombosis and pulmonary embolism among middle-aged men. DESIGN A prospective cohort study. SETTING General community, "The Study of Men Born in 1913. " SUBJECTS A random population sample of 855 men, all aged 50 years at baseline. MAIN OUTCOME MEASURES Eight-hundred fifty-five men participated in a screening examination in 1963 at the age of 50 years, and 792 of these men were reexamined in 1967 at the age of 54. All the men were followed up with periodic examinations until the age of 80. Objective methods were used to ascertain a diagnosis of deep vein thrombosis or pulmonary embolism. RESULTS Waist circumference (P=.004) and smoking (P = .02) predicted a venous thromboembolic event in multivariate survival analysis. Men in the highest decile of waist circumference (> or =100 cm) had an adjusted relative risk of 3.92 (95% confidence interval, 2.10-7.29; P<.001) compared with men with a waist circumference of less than 100 cm. For men who smoked 15 g of tobacco (15 cigarettes) a day or more, the adjusted relative risk was 2.82 (95% confidence interval, 1.30-6.13; P= .009) compared with nonsmokers. CONCLUSIONS Smoking and abdominal obesity were independent risk factors for venous thromboembolic events during follow-up. In addition to the prevention of smoking and obesity, a more aggressive strategy regarding the use of prophylactic agents among smokers and obese patients, in various risk situations, may be justified.
Standardization In The Home Building Industry: An Empirical Investigation Into The Compatibility Between Accounting And Estimating Cost Codes

The purpose of this study was to investigate the utilization of standardized cost codes for the estimating and accounting functions related to the scale of operations by Pennsylvania’s home building contractors. Firm size was examined as to its impact on three issues in construction standardization practice: 1) the use of a standardized number system for estimating, 2) the use of a standardized number system for accounting, and 3) the use of the same standardized number system for both estimating and accounting. Significant differences existed among firm sizes regarding all three items relating to standardized cost codes - a standardized numbering system used for estimating, a standardized numbering system used for accounting, and the same standardized numbering system used for both estimating and accounting functions . Overall, however, a large percentage of Pennsylvania home building firms are behind the curve with regard to their knowledge and utilization of standardized cost codes.
Stability of a Human SWI-SNF Remodeled Nucleosomal Array

ABSTRACT SWI-SNF alters DNA-histone interactions within a nucleosome in an ATP-dependent manner. These alterations cause changes in the topology of a closed circular nucleosomal array that persist after removal of ATP from the reaction. We demonstrate here that a remodeled closed circular array will revert toward its original topology when ATP is removed, indicating that the remodeled array has a higher energy than that of the starting state. However, reversion occurs with a half-life measured in hours, implying a high energy barrier between the remodeled and standard states. The addition of competitor DNA accelerates reversion of the remodeled array by more than 10-fold, and we interpret this result to mean that binding of human SWI-SNF (hSWI-SNF), even in the absence of ATP hydrolysis, stabilizes the remodeled state. In addition, we also show that SWI-SNF is able to remodel a closed circular array in the absence of topoisomerase I, demonstrating that hSWI-SNF can induce topological changes even when conditions are highly energetically unfavorable. We conclude that the remodeled state is less stable than the standard state but that the remodeled state is kinetically trapped by the high activation energy barrier separating it from the unremodeled conformation.
An Employee Engagement Productivity Study by Using Data Envelopment Analysis (DEA) (A Case Study of PT N)

NUR ANGEL MUTI’AH. An Employee Engagement Productivity Study by Using Data Envelopment Analysis (DEA) (A Case Study of PT N). Supervised by TAUFIK DJATNA Employee engagement (EGM) is an approach to determine how employee bounds at the company where they work at. This study aims to identify the variables that most influence on EGM and develop the best strategies to improve it. The higher the employee bounded to job satisfaction and organizational commitment, the better it affects the productivity of human resources in an organization. Identification of EGM responses were conducted by distributing questionnaires to employees where the Likert scale was applied. The result of the questionnaire was analyzed using Relief method. It generated 5 top rank variables that were most influential on EGM deployment. Data Envelopment Analysis (DEA) helped to determine the level of efficiency in each Decision Making Unit (DMU). The result indicated that the whole efficiency could be measured in the head office department. DEA method obtained efficiencies 5 department during 2013 and 2014 periods. EGM score influenced the evaluation sensitivity. The best strategy was to fulfill improvement projection as the target for each department, it is required to increase EGM score by keeping the 5 top rank variables.
Saturation by Noise and CW Signals in SIS Mixers

In ALMA Memo 321, Plambeck points out that saturation (gain compression) is likely to be a significant factor limiting the calibration accuracy of ALMA observations. In this memo, saturation by broadband noise and CW signals is analyzed for representative SIS receivers operating at different frequencies. Many SIS mixers in current use are expected to exhibit a significant degree of gain compression when connected to a room-temperature source. Previous analyses of saturation in SIS mixers have applied only to CW signals. To analyze saturation by noise, the statistics of the output voltage are derived from those of the input signal. A single constant, applicable to all SIS mixers, is determined experimentally by fitting the predicted CW gain compression curve to measured data.