Miracle-dz/UniFAR-FTUs huggingface dataset:
Reviewing and evaluating the functionality of top-rated mobile 1 apps for depression

3 Background: In the last decade, there has been a proliferation of mobile apps 4 claiming to support the needs of people living with depression. However, it is 5 unclear what functionality apps for depression actually provide and for whom they 6 are intended. 7 8 Objective: This paper aims to explore the key features of top-rated apps for 9 depression, including descriptive characteristics, functionality, and ethical concerns 10 in order to support better-informed design of apps for depression. 11 12 Methods: We reviewed top-rated iOS and Android mobile apps for depression 13 retrieved from app marketplaces in spring 2019. We applied a systematic analysis 14 to review the selected apps, for which data was gathered from the two 15 marketplaces, and through direct use of the apps. We report an in-depth analysis of 16 app functionality, namely: screening, tracking, and provision of interventions. Of the 17 initially identified 482 apps, 29 apps met the criteria for inclusion in this review. 18 Apps were included if they remained accessible at the moment of evaluation, were 19 offered in mental health relevant categories, received a review score greater than 20 4.0 out of 5.0 contributed by more than 100 reviewers, and have depression as a 21 primary target. 22 23 Results: The analysis revealed that a majority of apps specify the evidence-base for 24 their intervention (62%, 18/29) while a smaller proportion describe receiving 25 clinical input into their design (41%, 12/29). All selected apps are rated as suitable 26 for children and adolescents on the marketplace, but 83% (24/29) do not provide a 27 privacy policy consistent with their rating. Findings also show that most apps 28 provide multiple functions. The most commonly implemented functions include 29 provision of interventions (83%, 24/29) either as digitalized therapeutic 30 intervention or as support for mood expression, tracking (66%, 19/29) of moods, 31 thoughts or behaviors for supporting the intervention, and screening (31%, 9/29) to 32 inform the decision to use the app and its intervention. Some apps include overtly 33 negative content. 34 35 Conclusions: Currently available top-ranked apps for depression on the major 36 marketplaces provide diverse functionality to benefit users across a range of age 37 groups, however guidelines and frameworks are still needed to ensure users’ 38 privacy and safety while using them. Suggestions include clearly defining the age of 39 the target population and explicit disclosure of the sharing of users’ sensitive data 40 with third parties. Additionally, we found an opportunity for apps to better leverage 41 digital affordances for mitigating harm, for personalizing interventions, and for 42 tracking multimodal content. The study further demonstrates the need to consider 43 potential risks while using depression apps, including the use of non-validated 44 screening tools, tracking negative moods or thinking patterns, and exposing users to 45 negative emotional expression content. 46 47
Objective knowledge an evolutionary approach pdf

Popper: Books.Objective knowledge : an evolutionary approach Karl R. Karl nya journal june 2010 pdf Raimund, 1902-1994 View online Borrow Buy.distinction between subjective and objective knowledge constitutes one of the central themes in. Evolutionary Approach Oxford: Clarendon, 1972, 311.The essays in this volume represent an approach to human knowledge that has had a profound influence on many recent thinkers.
Study of Healthcare-Associated Infections and Multi-Drug Resistance in Brooklyn: An Integrative Approach

One SENCER ideal is to connect science education and civic engagement by student learning through complex, unresolved public issues. Using this approach, we established a collaborative interdisciplinary project involving faculty and undergraduate students at NYC College of Technology. Over several semesters, students conducted literature search and discovered the complex factors contributing to the occurrence and transmission of healthcare-associated infections (HAIs). Using microbiology data from 15 hospitals in Brooklyn, NY, they applied statistical analyses, studied the antibiotic resistance, and developed a campaign to bring more awareness of this problem. The results of the project highlight the importance of immediate action in combating HAIs and support the need for a public health campaign. Undergraduate students were provided with the opportunity to conduct research, perform scientific and mathematical analyses, and present their results. They gained better understanding of the complex interactions among microbiology, epidemiology, and mathematics that is needed to develop preventative measures and combat HAIs.
SPILL OVER EFFECTS OF OPERATIONAL LOSS EVENTS WITHIN THE SOUTH AFRICAN BANKING SECTOR

This study analysed return volatility after operational loss announcements concerning major South African banks during 2000-2014. The sample of banks that experienced losses over the sample period was compared with a sample of unaffected banks, the banking index and the stock market index, to identify whether the operational loss announcements had spill over effects on the whole South African banking sector. Daily share returns were analysed using event study methodology and the weighted moving average (EWMA) model. On one hand, the results showed that the operational loss events for two of the affected banks exerted no effect on the number of unaffected banks. On the other hand, the operational loss events for the two remaining banks were found to have spill over effects. The returns of the unaffected banks as well as the whole banking sector were effected, which led to systemic risk. However, results revealed that operational losses in the South African banks did not spill over to the stock market. Overall, the findings indicate that the effect of operational losses may depend on the level of integration between individual banks.
How Does Islamic Financial Technology Influence Debtors’ Preference in Islamic Rural Bank

This paper analyses the influence of Islamic Financial Technology on the change in Debtors’ Preference for Bangun Drajat Warga Islamic Rural Bank Bantul, Special Region of Yogyakarta. The influence of Islamic Financial Technology is measured using several variables, comprising Perceived Financial Technology, Service Feature, Perceived Ease of Use and Perceived Risk. The paper, which is in the form of a case study on Bangun Drajat Warga Islamic Rural Bank Bantul, Special Region of Yogyakarta, was conducted from September to October 2018. Primary data were collected through the use of a questionnaire and interview and were processed using SPSS15 and analysed using Multiple Linear Regression. The results show that Perceived Financial Technology, Service Feature and Perceived Ease of Use partially have a significant and positive influence on the change in Islamic Rural Bank Debtors’ Preference. The variable Perceived Risk was the only one to have an insignificant and negative influence on the change in Islamic Rural Bank Debtors’ Preference. Overall, the independent variables simultaneously have a significant influence on the change in Islamic Rural Bank Debtors’ Preference. The independent variables explained 63.3% of the dependent variables, with the remaining 36.7% explained by other variables outside the model. Keywords—Financial Technology, Debtors Preference, Islamic Rural Bank
HYBRID APPROACH FOR AUTOMATIC SHORT ANSWER MARKING

E-assessment is a key element in any e-learning system, needed to evaluate the learning process. It can be successfully and easily carried out on Multiple Choice Questions (MCQs). However, e-assessment of essay questions is much harder than that of MCQs. Consequently, it is a growing area of research. This paper presents an approach to assess short answer questions automatically through integrating the Information Extraction (IE) technique and Decision Tree Learning (DTL), a Machine learning (ML) technique. The IE technique employs Natural Language Processing (NLP) tools such as parsers and lexicon. Additionally, the Machine Learning techniques automate the free-text marking using the classification rules that are extracted from DTL and used to assess the student's answer. Index Terms – E-assessment, E-learning, NLP, IE, DTL.
Variational Learning with Disentanglement-PyTorch

Unsupervised learning of disentangled representations is an open problem in machine learning. The Disentanglement-PyTorch library is developed to facilitate research, implementation, and testing of new variational algorithms. In this modular library, neural architectures, dimensionality of the latent space, and the training algorithms are fully decoupled, allowing for independent and consistent experiments across variational methods. The library handles the training scheduling, logging, and visualizations of reconstructions and latent space traversals. It also evaluates the encodings based on various disentanglement metrics. The library, so far, includes implementations of the following unsupervised algorithms VAE, Beta-VAE, Factor-VAE, DIP-I-VAE, DIP-II-VAE, Info-VAE, and Beta-TCVAE, as well as conditional approaches such as CVAE and IFCVAE. The library is compatible with the Disentanglement Challenge of NeurIPS 2019, hosted on AICrowd, and achieved the 3rd rank in both the first and second stages of the challenge.
Modeling Communities in evalue

Increasingly, communities play an important role in business value models. However, in evalue , there seems not to be a suitable construct to model communities. In this paper, we propose an additional concept that can be used for communities, namely the “group”. We illustrate the use of this concept for understanding a business model in the field of ICT4D (ICT for developing countries). abstract environment.
Diffusion of Innovation: A Descriptive Analysis of Pediatric Preparedness in Emergency Departments

DIFFUSION OF INNOVATION: A DESCRIPTIVE ANALYSIS OF PEDIATRIC PREPAREDNESS IN EMERGENCY DEPARTMENTS Kathi C. Huddleston, Ph.D. George Mason University, 2007 Dissertation Director: Dr. P.J. Maddox The purpose of this study was twofold: First, to identify essential pediatric resuscitative equipment gaps in the nation’s emergency departments; second, to identify associations among and between the domains of community and health care organizational structure as they related to hospital emergency departments’ (EDs) adoption of the 2001 “Care of the Child in the Emergency Department: Guidelines for Preparedness” (Guidelines for Preparedness) published by the American Academy of Pediatrics (AAP) and the American College of Emergency Physicians (ACEP). Diffusion of Innovation (DOI) is the theoretical concept by which multiple characteristics within the domains of health care structure and community were examined. The study was conducted using extant data from the Center for Disease Control and Prevention (CDC) branch of the National Center for Health Statistics (CDC/NCHS). This descriptive study examined the relationships regarding the organizational and community characteristics of emergency departments with the adoption of the Guidelines for Preparedness. Characteristics of pediatric patient volume, pediatric subspecialty services, per capita income, urbanicity, and region were associated with the availability of pediatric emergency care essential equipment and services. Logistic regression was used to further explore variable relationships. The study identified hospital and community characteristics associated with pediatric emergency readiness and emergency medical care services essential for the care of critically ill or injured children. The study’s community variables of per capita income and metropolitan status were significant, as were the structure variables of pediatric ED volume (size), pediatric trauma service, the presence of pediatric emergency medicine, and being a pediatric hospital. The DOI concepts of complexity and interconnectedness were drivers in both the adoption of the Guidelines for Preparedness and the compliance with pediatric essential emergency equipment. This study affirms that pediatric emergency equipment availability is a problem. Pediatrics continues to be an afterthought in emergency and disaster management, and as a nation we are not prepared for pediatric emergencies or pediatric disaster care.
Producing and disseminating marginalized knowledge through students’ drawings, videos and crafts

Can multimodality contribute to the social inclusion of all students and to fostering of a democratic culture in educational settings characterized by major population movements and relevant social changes that usually promote racism and exclusion? In this paper, we argue that multimodality, especially its social semiotic approach (Kress, 1995, 2009; Kress & van Leeuwen, 2001; van Leeuwen, 2005), is not just another necessary addendum to the curriculum for “new learning” (adjusted to the needs of contemporary societies and new technologies). More importantly, it can offer democratic ways to produce, distribute and disseminate knowledge. Having worked with the Knowledge Democracy initiative (Sousa Santos, 2018) in an Erasmus+ Project called Backpack-ID, developed as a bottom-up innovation in participating schools, we demonstrate, through specific examples, that the students’ drawings and digital storytelling can create prospects for social inclusion for all students in the classroom. More specifically, we try to show, in detail and through instances of practice, how a classroom, as a multi-semiotic space, can become a democratic space founded on the inclusion of diverse histories, memories, languages, identities and epistemologies.
Comparative epidemiological study of non‐melanoma skin cancer between Spanish and north and central European residents on the Costa del Sol

Background Non‐melanoma skin cancer (NMSC) is the most common tumour in white people. The progressive increase of these malignancies in such populations as those found in Europe represents an important public health concern which it is presumed will have a great impact on healthcare costs. However, the lack of comparable epidemiological information between countries hinders the development of a common health policy.
Tratamiento clínico de un paciente con periodontitis crónica avanzada generalizada en la Facultad de Odontología de la Universidad de Antioquia, Medellín, Colombia: reporte de un caso

La enfermedad periodontal afecta la salud del paciente comprometiendo la forma, funcion y estetica del sistema estomatognatico, llevando a un deterioro notable de la calidad de vida de las personas. En este caso clinico se presenta el tratamiento integral de un paciente de sexo masculino de 43 anos de edad con periodontitis cronica avanzada generalizada que incluyo: tratamiento periodontal no quirurgico, quirurgico y de rehabilitacion oral, hecho durante dieciocho meses por un estudiante de ultimo ano del pregrado y un grupo de docentes especialistas en periodoncia y rehabilitacion oral bajo la modalidad docencia-asistencial de la Facultad de Odontologia de la Universidad de Antioquia (Medellin, Colombia).
Differences in risk of malignancy and management recommendations in subcategories of thyroid nodules with atypia of undetermined significance or follicular lesion of undetermined significance: the role of ultrasound-guided core-needle biopsy.

BACKGROUND The cytopathologic description of atypia of undetermined significance (AUS)/follicular lesion of undetermined significance (FLUS) includes nine different criteria in The Bethesda System, and the risk of malignancy in this category shows a wide range. The objectives of the present study were to determine whether ultrasound (US)-guided core-needle biopsy (CNB) indicates a different malignant risk, and to identify management recommendations, malignant US findings, and distribution of CNB readings in subcategories of AUS/FLUS category, as seen on previous thyroid fine-needle aspiration readings. METHODS From October 2008 to July 2011, 191 thyroid nodules of 191 patients who had previously been diagnosed with nuclear atypia (Group AUS; n=84) and microfollicular architecture (Group FLUS; n=107) were enrolled in our retrospective study. Final diagnoses were obtained in 142 nodules after surgery and clinico-radiological follow-up. We compared the malignancy risk, management recommendation, malignant US findings, and distribution of CNB readings between the two groups and calculated the diagnostic value of CNB. RESULTS With CNB, the final malignancy results were greater in Group AUS (65%, 33/51) than Group FLUS (14.3%, 13/91; p<0.001), and there were more surgical candidates in Group AUS (57.8%, 46/84) than Group FLUS (19.6%, 21/107; p<0.001). CNB showed 95.8% diagnostic accuracy for identifying malignancies and 19.4% inconclusive readings. Malignant US findings were seen more frequently in Group AUS (76.5%, 39/51) than Group FLUS (52.7%, 48/91; p=0.007). Malignant CNB readings were statistically more frequent in Group AUS (49.2%, 41/84) than Group FLUS (9.4%, 10/107; p<0.001), and benign readings were statistically more frequent in Group FLUS (58.9%, 63/107) than Group AUS (28.6%, 24/84; p<0.001). CONCLUSIONS US-guided CNB demonstrated that Group AUS showed a higher risk of malignancy, of becoming surgical candidates, of having malignant US findings, and of having malignant CNB readings than Group FLUS. Further management guidelines for Group AUS should differ from Group FLUS.
PREVALENCIA DEL RESULTADO DE CITOLOGÍA DE CÉLULAS ESCAMOSAS ATÍPICAS QUE NO EXCLUYE LESIÓN INTRAEPITELIAL DE ALTO GRADO (ASC-H), EN DOS INSTITUCIONES DE BOGOTÁ (COLOMBIA), 2006-2013

Objective: To determine the prevalence of the finding of atypical squamous cells cannot exclude high-grade squamous intraepithelial lesions (ASC-H) in two pathology centres, and to determine the prevalence among those cytology findings of high grade squamous intraepithelial lesion (HSIL) on biopsy. Materials and methods: Cross-sectional study including all patients undergoing cytology in two colposcopy centres in Bogota, one in a public hospital and the other in a private centre, during the period between 2006 and 2013. ASC-H cytology results were identified in a sample of consecutive cases, and the assessment included the social and demographic characteristics of the patients and the colposcopy and biopsy results. The analysis focuses on the prevalence of the ASC-H result and of the HSIL result on histopathology. Results: Overall, 357 ASC-H cytology results were identified out of 23,960 abnormal cytology findings, leading to an estimated prevalence of 1.49% (95% CI, 1.34-1.64). Histopathology was required in 230 cases (65%) and the prevalence among them of HSIL was 26.5%. Conclusions: The results of this study showed a prevalence of 1.49% for ASC-H. Given that an important number of patients have a high-grade intraepithelial lesion, colposcopy-guided biopsy is recommended in patients with this result.
p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression

We studied 53 patients with B-cell chronic lymphocytic leukemia (B-CLL) and found mutations of the p53 gene in 15%. Patients with p53 gene mutations were found to have an aggressive form of B-CLL disease characterized by advanced Rai stage, rapid lymphocyte doubling time (LDT), and resistance to chemotherapy. While 27 of 29 treated patients (93%) without p53 mutations achieved a partial remission, only one of seven treated patients (14%) with p53 mutations achieved a partial remission (P = .00009). Adjusting for prognostic factors (age, sex, race, and Rai stage), patients with p53 gene mutations had a 13-fold greater risk of death than patients without p53 mutations (P = .013). In addition to examining the clinical relevance of p53 gene mutations in B-CLL, we investigated the possible role of p53 gene regulation in the expression of the multidrug resistance genes MDR1 and MDR3. We quantitated MDR1 and MDR3 mRNA expression by reverse transcription- polymerase chain reaction (RT-PCR). Expression of both the MDR1 and MDR3 genes was independent of p53 gene mutation or prior drug treatment, and did not predict for clinical response. Our findings indicate that p53 gene mutations in B-CLL are associated with a poor clinical outcome and may be a prognostic indicator for drug resistance.
Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera

Thrombohemorrhagic complications are a major cause of morbidity and mortality in patients with essential thrombocythemia (ET) and polycythemia vera (PV). The pathogenesis of these complications is not completely clarified. Several studies have described abnormalities of red blood cells and platelets in these patients. However, no studies are available on changes in the polymorphonuclear leukocytes (PMNs), which can play an important role in the activation of the hemostatic system. In patients with ET (n = 37) and PV (n = 34), a series of PMN activation parameters (PMN membrane CD11b and leukocyte alkaline phosphatase [LAP] antigen expression, cellular elastase content, plasma elastase, and myeloperoxidase levels) was evaluated simultaneously with the levels of plasma markers of endothelial damage (thrombomodulin and von Willebrand factor antigen) and hypercoagulation (thrombin-antithrombin complex, prothrombin fragment 1 + 2, and D-dimer). The results show the occurrence of PMN activation in both groups of patients compared with a control group of healthy subjects. An increase in CD11b and LAP expression by PMN membrane was observed, together with a significant increase in cellular elastase content, plasma elastase, and myeloperoxidase levels. In addition, patients had high plasma levels of endothelial and hypercoagulation markers compared with controls. For the first time, these data show that in ET and PV, 2 hematologic conditions that place patients at increased risk for thrombosis, an in vivo leukocyte activation occurs and is associated with laboratory signs of endothelium and coagulation system activation.
From Whole Exome Sequencing to Patient-Specific Therapy: Another Example of How Basic Research Pays Off in Patient Care

In the past 20 years, molecular genetics has successfully entered the arrhythmia field. [1][1]–[2][2] The identification of the genetic basis of many of the arrhythmia syndromes provided us the tools for better understanding of the pathophysiological basis of these syndromes,[2][2] for
Hematologic Abnormalities in Fanconi Anemia: An International Fanconi Anemia Registry Study

We analyzed data from 388 subjects with Fanconi anemia reported to the International Fanconi Anemia Registry (IFAR). Of those, 332 developed hematologic abnormalities at a median age of 7 years (range, birth to 31 years). Actuarial risk of developing hematopoietic abnormalities was 98% (95% confidence interval, 93% to 99%) by 40 years of age. Common hematologic abnormalities were thrombocytopenia and pancytopenia. These were often associated with decreased bone marrow (BM) cellularity (75% of cases studied). Clonal cytogenetic abnormalities developed in 23 of 68 persons with BM failure who had adequate studies. Actuarial risk of clonal cytogenetic abnormalities during BM failure was 67% (47% to 87%) by 30 years of age. Fifty-nine subjects developed myelodysplastic syndrome (MDS) or acute myelogenous leukemia (AML). Actuarial risk of MDS or AML was 52% (37% to 67%) by 40 years of age. Risk was higher in persons with than in those without a prior clonal cytogenetic abnormality (3% [0% to 9%] v 35% [0% to 79%]; P = .006). One hundred twenty persons died of hematologic causes including BM failure, MDS or AML and treatment related complications. Actuarial risk of death from hematologic causes was 81% (67% to 90%) by 40 years of age.