Miracle-dz/UniFAR-FTUs huggingface dataset:
Security Operations Center: A Framework for Automated Triage, Containment and Escalation

There have been a lot of research exertions and studies to improve the safety of critical infrastructures using the Security Operations Center (SOC). As part of efforts, the purpose of this research is to propose a framework to automate the SOC’s performance of triage, containment and escalation. The research leveraged on qualitative desk review to collect data for analysis, deduced strengths and weaknesses for the current SOC implementations and used that as a basis for proposing the framework. In view of the constant evolution of SOC operations and capabilities coupled with the huge volumes of data collected for analysis, an efficient framework for SOC operations is proposed. The qualitative analysis is used to deduce strengths and weaknesses for the current SOC implementations as a premise for proposing the framework. It consists of eight interactive stages that further leverage on a proposed algorithm for baselining, remediation and escalation. The result of this research is a proposed framework that serves as a unique contribution to enhancing the SOC’s ability to automatically perform triage, containment and escalation. Supplementary to similar and earlier work reviewed, the framework is proposed as the way forward to automatically enable SOC setups with the capacity to efficiently perform triage of security threats, vulnerabilities and incidents, effectively contain identified breaches and appropriately escalate for prompt and accurate solutions.
Odeurs indésirables de la viande de porcs mâles non castrés : problèmes et solutions potentielles

La présence d’odeurs indésirables dans la viande de porcs mâles entiers est principalement liée à l’accumulation d’androsténone et de scatol. L’androsténone est synthétisée par les testicules et le scatol par les bactéries du colon à partir du tryptophane. Leur teneur dans le tissu adipeux résulte du bilan entre leur synthèse, leur élimination et leur réabsorption. Le principal levier d’action pour réduire la teneur en androsténone est la sélection génétique. Pour le scatol, les principaux leviers d’action concernent la conduite d’élevage : propreté des cases, gestion de l’environnement microclimatique et conduite alimentaire, notamment. La mixité des groupes et l’instabilité sociale ont peu d’impact sur les teneurs en composés odorants, mais sont importantes à contrôler pour réduire les risques de bagarres et de lésion. Même en réduisant fortement la teneur en composés odorants, il ne sera pas possible d’obtenir des niveaux indétectables sur toutes les carcasses. Une stratégie d’utilisation des carcasses odorantes de porcs mâles entiers doit être définie. Elle implique de comprendre les facteurs de rejet des viandes odorantes par les consommateurs. La perception d’odeurs sexuelles dépend de facteurs liés à l’animal, au type de produit, au mode de préparation/consommation et au consommateur lui-même. De plus, les deux molécules odorantes semblent interagir. La prise en compte des différents cas de figure peut être envisagée par une approche de modélisation, avec en préalable la mise en œuvre d'une détection des odeurs sur la chaine d’abattage. Or actuellement, seule la détection par le nez humain est opérationnelle au niveau des chaines d’abattage et des méthodes instrumentales restent à développer.
Flash photography does not induce stress in the Ram cichlid Mikrogeophagus ramirezi (Myers & Harry, 1948) in aquaria

The Ram cichlid Mikrogeophagus ramirezi (Myers & Harry, 1948) was used to examine whether flash photography can be a stressor for fish in aquaria. The point in time of the highest cortisol concentration in whole‐body homogenates was determined by the temporal course of the cortisol response following air exposure as stressor. Thus, the potential stress response to camera flashlight was examined 22 min after exposure to a single flash and after repeated flashes by applying 10 flashes per minute for 8 hr/day over 2 weeks. In both experiments the stress parameters cortisol and glucose were not increased due to exposure to the flash light. In contrast, after a single flash mean cortisol values tended to be lower and mean glucose values were significantly lower than in the control group, and after repeated flashes mean cortisol and glucose values were significantly lower than in the control group. Furthermore, treated fish showed less intraspecific aggressive interactions. These results can be explained by a possible dazzling or irritation of the fish by camera flashes, thus reducing the natural aggressive behaviour and, consequently, the concentration of stress hormones and mobilisation of glucose. In summary, the physiological stress parameters cortisol and glucose do not reveal that flash photography induces stress in M. ramirezi, and, on the contrary, might even reduce stress effects by lowering intraspecific aggressive behaviour of the fish.
Diffusion and catalyst efficiency in hierarchical zeolite catalysts

Abstract The preparation of hierarchical zeolites with reduced diffusion limitation and enhanced catalyst efficiency has become a vital focus in the field of zeolites and porous materials chemistry within the past decades. This review will focus on the diffusion and catalyst efficiency of hierarchical zeolites and industrial catalysts. The benefits of diffusion and catalyst efficiency at two levels of hierarchies (zeolitic component level and industrial catalyst level) from a chemical reaction engineering point of view will be analysed. At zeolitic component level, three types of mesopores based on the strategies applied toward enhancing the catalyst effectiveness factor are presented: (i) ‘functional mesopores’ (raising effective diffusivity); (ii) ‘auxiliary mesopores’ (decreasing diffusion length); and (iii) ‘integrated mesopores’ (a combination thereof). At industrial catalyst level, location and interconnectivity among the constitutive components are revealed. The hierarchical pore interconnectivity in multi-component zeolite based industrial catalysts is exemplified by fluid catalytic cracking and bi-functional hydroisomerization catalysts. The rational design of industrial zeolite catalysts at both hierarchical zeolitic component and catalyst body levels can be fully comprehended using the advanced in situ and/or operando spectroscopic, microscopic and diffraction techniques.
Inhibition of SYK More Effectively Overcomes MCL-1 Mediated ABT-199 Resistance of BCR-Stimulated CLL Cells Than Inhibition of BTK or PI3Kdelta

The selective Bcl-2 antagonist ABT-199 has demonstrated promising clinical activity in patients with CLL. This drug is strongly cytotoxic against unstimulated peripheral blood CLL cells in vitro, but is much less effective against CLL cells that have received signals mimicking interactions with the lymph node microenvironment. In particular, stimulation of peripheral blood CLL cells with CD40L and IL-4 results in substantial resistance, which is mediated by induction of the antiapoptotic Bcl-2 family proteins Bcl-XL and Bfl-1. In the present study, we investigated whether resistance to ABT-199 can be conferred by engagement of the BCR, which is another stimulus that CLL cells receive primarily in the lymph nodes. Sustained engagement of the BCR with immobilized anti-IgM antibody, which is commonly used as a surrogate for a membrane-bound antigen, significantly protected CLL cells from ABT-199-mediated apoptosis (n=28; % viable CLL cells after 24 hours in culture without ABT-199: 52.2±14.8; with 2nM ABT-199: 28.3±15.1, with 2nM ABT-199 and immobilized anti-IgM: 43.0±19.5, P Disclosures No relevant conflicts of interest to declare.
Peer reviewing made easier: your questions answered

SUMMARY Peer reviewing is a hugely important part of the scientific process that ensures published articles are of sufficient quality to deserve dissemination to the wider scientific community. Building on a previous article published in this journal, this article addresses topics that potential or practising peer reviewers may find useful. These include what peer reviewing is, why do peer reviews, how to become a reviewer, what to write in a review and where to find more information. It includes a template for writing a review, and lists various websites and guidelines that can help ease the entire process depending on what type of article is being reviewed. Peer reviewing can be enormously rewarding and help clinicians diversify their scope of work while also benefiting the scientific community by contributing to the quality control of published work.
When embeddedness hurts: the moderating effects of job embeddedness on the relationships between work-to-family conflict and voluntary turnover, emotional exhaustion, guilt, and hostility

Abstract Theory and research have focused mainly on negative aspects of work-to-family conflict (WFC) and positive aspects of job embeddedness on a range of outcomes. However, due to the lack of research integrating these constructs, less is known what happens when working parents high on embeddedness face WFC. This study uses the conservation of resources theory to examine moderating effects of on-the-job embeddedness between the relationships of WFC and four outcomes: voluntary turnover, emotional exhaustion, guilt, and hostility. Data were derived from 724 working mothers in Japan at three points in time over a 14‐month time period. Results show that while respondents high on on-the-job embeddedness facing WFC had lower voluntary turnover, they reported more emotional exhaustion, guilt, and hostility. The findings contribute to the literature by linking WFC to specific emotion-related outcomes and by providing evidence of the “dark side” of job embeddedness.
Microelectrode Combinations of Gold and Polypyrrole Enable Highly Stable Two‐electrode Electrochemical Impedance Spectroscopy Measurements under Turbulent Flow Conditions

: An electrochemical impedance spectroscopy (EIS) sensor design is proposed based on a standard interdigitated electrode layout in which the smaller working electrode consists of gold (Au) whereas the larger combined counter and reference electrode is coated with a porous layer of polypyrrole (PPy) doped with polysty-rene sulfonate (PSS) (PPy:PSS). Each electrode material was first characterized by EIS in a standard 3-electrode setup with subsequent spectra fitting by a modified Randles equivalent circuit. The differences in the spectra obtained by the PPy:PSS coated electrodes can be explained by an increased electroactive surface area due to the porous polymer film. The changes in morphology of the film are discussed with respect to the evolution of the elements of the electric equivalent circuit. When applying the Au/PPy:PSS electrode combination to a standard 2-electrode arrangement, the enlarged highly electroactive surface area of the PPy:PSS coating lowers the interfacial impedance in a way that mainly the gold working electrode contributes to the overall system impedance. Therefore, obtaining reproducible EIS signals depends only on the electrode’s open-circuit potential (OCP) and on additional adsorption events at the gold electrode/electrolyte interface. We present a protocol for microelectrode coating with PPy:PSS, which enables highly stable 2-electrode EIS experiments without the need of a reference electrode. This combination is believed to be very useful if an integration of sensing electrodes inside Micro Total Analysis Systems is aspired.
Model approach for electromagnetically excited mechanical vibrations in direct-drive wind turbines

In this paper a multi-physical modelling approach for calculating parasitic magnetic force excitations in wind turbine generators is presented. These parasitic excitations are dependent on the magnetic field distribution in the air gap and the air gap geometric shape, which is dependent on the external loads of the wind turbine. With this methodology mechanical multibody simulation is coupled with electromagnetic field calculation by means of finite-element calculation. First the general methodology and the calculation of the air gap width distribution is presented and subsequently the electromagnetic field and force calculation is explained.
Composition of Clay Filters for Water Treatment in Akutuase: A Rural Community in Western Region, Ghana

The purpose of this study was to compose clay filters made from local materials for the efficiency of water impurities removal for rural households. Clay filters were manufactured by using local materials: Akutuase clay, sawdust gathered from a sawmill unit, and rice husks from rice farmers at Akutuase. These materials were ground and sieved to obtain finer particle sizes, weighed, and proportionally wet mixed. Pots were then made, dried, and fired in a kiln at temperatures of 850, 900, and 950oC, respectively. A silver coating was artificially applied to the fired filters using 0.1 mg/L of silver solution. Raw water fetched from a stream in Akutuase was filtered using the pots. The filtered water was tested for microbial removal efficiency of the composed clay filters at Ghana Water Company, Takoradi. It was revealed that compositions $C_380$ and $C_480$ made up of 80% clay, 15% rice husks and 5% sawdust that were fired at 900 and 950oC respectively, became successful and suitable for water filtration. However, it was highly successful when the temperature was 950oC due to comparatively the greater quantity of water that $C_480$ was able to filter. The results suggested that the silver-impregnated ceramic filter constructed was highly efficient and effective in the removal of bacteria. It had been recommended among others that, as a measure to prevent water-borne diseases in Akuatuase, institutions should invest in setting up small scale ceramic industry in the community for mass-production of clay filters to serve the rural folks. Further studies should be extended to analyze the removal of other pathogens including viruses and protozoa for different water-quality conditions. Additionally, the long-term field performance of locally produced filters and their effects on human health must be investigated.
The impact of vitamin D: From a fetus to an infant

The focus of this paper is to review the data on the classic and nonclassic role of VD with regards to pregnancy and the newborn period. Over the past decade, new evidence has shown that vitamin D (VD) deficiency, in addition to its classical role in calcium metabolism and bone homeostasis, may contribute to the risk of developing a wide range of chronic diseases. VD may produce a wide array of favourable biological effects via genomic, non-genomic or intracrine mechanisms, and therefore contributes to the improvement of human health. Some of these effects may be even more important during pregnancy. Data from animal and human studies implicate maternal VD deficiency as a significant risk factor for several adverse outcomes affecting maternal, foetal and child health. In the newborn period, these comprise bone health, growth and immune response. Conclusion − Recent evidence supports the fact that low maternal vitamin D status is associated with an increased risk of adverse pregnancy outcomes. This paper investigates the effects of vitamin D on the placento-foetal unit and the mother, in terms of calcium metabolism and non-calcium effects.
Roles of Nitrogen Deep Placement on Grain Yield, Nitrogen Use Efficiency, and Antioxidant Enzyme Activities in Mechanical Pot-Seedling Transplanting Rice

Mechanical pot-seedling transplanting (PST) is an efficient transplanting method and deep nitrogen fertilization has the advantage of increasing nitrogen use efficiency. However, little information is available about the effect of PST when coupled with mechanized deep nitrogen (N) fertilization on grain yield, nitrogen use efficiency, and antioxidant enzyme activities in rice. A two-year field experiment was performed to evaluate the effect of PST coupled with deep N fertilization in both early seasons (March–July) of 2018 and 2019. All seedlings were transplanted by PST and three treatments were designed as follows. There was a mechanized deep placement of all fertilizer (MAF), broadcasting fertilizer (BF), no fertilizer (N0). MAF significantly increased grain yield by 52.7%. Total nitrogen accumulation (TNA) was enhanced by 27.7%, nitrogen partial factor productivity (NPFP) was enhanced by 51.4%. nitrogen recovery efficiency (NRE) by 123.7%, and nitrogen agronomic efficiency (NAE) was enhanced by 104.3%, compared with BF treatment. Moreover, MAF significantly improved peroxidase (POD), catalase (CAT), and notably reduced the malonic dialdehyde (MDA) content for both rice cultivars, compared to BF. Hence, the result shows that mechanical pot-seedling transplanting coupled with nitrogen deep placement is an efficient method with the increase of grain yield and nitrogen use efficiency in rice cultivation in South China.
Towards application of light detection and ranging sensor to traffic detection: an investigation of its built-in features and installation techniques

Abstract In transportation, LiDAR sensors have been primarily used in surveying and autonomous driving as a major onboard sensing device to detect field objects. Recently, with reduced price and increased demand from real-time and trajectory-level traffic detection, LiDAR technology sees great potential for becoming a mainstream means of infrastructure-based traffic detection other than only being used onboard. In addition to its many advanced features, LiDAR is much less impacted by illumination conditions compared to video sensors and significant in data processing speed, which makes it ideal for real-time traffic detection. The research team has conducted a wealth of studies to investigate the feasibility of installing LiDAR sensors at the roadside to obtain trajectories of automobiles and pedestrians at a frequency of 10 Hz. While our findings on how to process roadside LiDAR data have been presented in other literatures, this paper reveals our findings on another important issue regarding roadside LiDAR application – installation strategies to achieve the best performance. The authors first developed a theoretical approach based on the analysis of the built-in features of the applied LiDAR sensors and followed the results to install the sensors in our testbed. Then, experimental studies were conducted onsite and examined the theoretical results accordingly. As a result, a technical guidance for proper installation of LiDAR sensors at the roadside for the best real-time and trajectory-level traffic detection was produced. This study helps researchers and practitioners in better preparing for future deployment of roadside LiDAR sensors as part of the connected vehicles and infrastructures.
An evaluation of the technique of use of metered dose inhaler administration in bronchial asthma children

Background: Inadequate understanding and performance of drug administration using metered-dose inhaler (MDI) in paediatric population affects therapeutic outcome. Hence, this study aimed to evaluate the impact of two educational interventional methods for usage of MDI in paediatric patients of bronchial asthma. Methods: This prospective, interventional study was done in paediatric asthma patients who were prescribed drugs with (MDI) with/without spacer at outpatient department of pediatrics. Patients were divided in group A (video) or group B (leaflet) as per random table method and method to use MDI was assessed by using checklist as per WHO guide to good prescribing at baseline. Investigator taught the technique by a video (group A) and leaflet (group B) to the selected population. Patients were followed up after 15 days and assessed for use of MDI using the same checklist. Data were analysed by using paired and unpaired ‘t’-test. Results: A total of 100 pediatric asthma patients were included in study group A (50) and group B (50). The average no. of steps (WHO checklist) followed was significantly improved at post intervention in both group A (with spacer, p<0.0001) as well as B (without spacer, p<0.05). Although average no. of steps followed were more in group A, no significant difference was found between two groups after intervention. Conclusions: As video is an audio-visual method of demonstration, and hence help us memorise the step of inhalational technique in pediatric patients. Repeated demonstration/education to patients/caregivers may improve the method of MDI usage.
EXPLORING THE POTENTIAL OF TRAFFIC INDEX DATA TO ANALYZE ESSENTIAL TRAFFIC IMPACT IN DEVELOPING CITIES

Abstract. In developing countries, metropolitan cities, due to their economic activities, attract an increasing amount of commuters on a daily basis. This has led to major freeways and roads experiencing high levels of congestion and consequently high pollution levels. In 2020, due to a global pandemic of an outbreak of Corona Virus (COVID-19), the national government declared a national shutdown with only essential traffic being allowed to operate. Given the scenario of the national lock-down this allows for the statistical analysis of the impact of essential traffic on the overall transportation system. Consequently the aim of the paper was to assess the congestion and CO2 emission impact of essential traffic for the City of Johannesburg. Using an exploratory approach, we monitored and collected traffic congestion data from the Tomtom traffic index for the metropolitan city of Johannesburg, South Africa. We develop a relationship between congestion and pollution to visualise the daily variations in pollution and congestion levels. We demonstrate this by comparing variations in congestion levels in two epochs, viz the period without movement restrictions and the period whereby movement is restricted. The results reveal essential traffic on the congestion index to be below 22 percent for both weekends and weekdays. A scenario common only during weekends in 2019. Whilst for the emission index, CO2 levels are approximately less than 45 percent throughout the week. The paper concludes the investment into mining and analysing traffic data has a significantly role for future mobility planning in both the developed and developing world and, more generally, improving the quality of commuting trips in the city.
Comprehensive Financial Analysis of Liquor Industry in China

Comprehensive financial analysis, which is based on the company’s financial report, using a series of analysis methods to reflect the company’s financial situation and business performance. Comprehensive financial analysis can provide investors, managers and other information users with more real, concise and credible information. With the continuous improvement to people’s consumption level in China, the market demand for liquor keeps increasing, which brings liquor industry an inexhaustible driving force for sustainable development. Although the industry experienced a downturn in 2012 due to the government’s restrictions on official consumption, liquor industry as a whole developed well. This paper uses the comprehensive financial analysis method to investigate the development of liquor industry, and we find that liquor industry is developing in a more stable and standardized direction. Finally, we forecast the future development trend of the industry in order to provide reference value for the investors.
TETRANEXT IN THE TOPICAL TREATMENT OF MINOR RECURRENT APHTHOUS STOMATITIS

Review. The averaged anthropometric data for the groups are given in Тable1 and significant differences in the power of spectral characteristics for all indicators of the frequency spectrum were established by us (Table 2). Table 2 General indicators of spectral characteristics of the Heart Rate Variability Group n1=60 Group n2=23 Background recording Orthostatic test Background recording Orthostatic test