Miracle-dz/UniFAR-FTUs huggingface dataset:
Hybrid inverse dynamics control of a free-flying space robot in contact with a target satellite

This paper presents an inverse-dynamics-based control approach of a free-flying space robot manipulator interacting with a target satellite. The proposed controller handles the overall combined coupled dynamics of the based-satellite servicing robot and the passive target satellite all together with geometric and momentum constraints imposed on the system. A reduced-order dynamical model is obtained by finding a common solution of all constraints using the concept of orthogonal projection matrices. The proposed controller does not only show the capability to meet motion and contact forces desired specifications, but also to cope with the unactuation problem of the target satellite due to its thrusters' failure or shutdown. Finally, simulation results demonstrate the effectiveness of the proposed controller
Taking a New-Generation Manager Perspective to Develop Interface Designs

Digital natives are increasingly populating organizations' management. As they have higher expectations with respect to IS accommodating their (non-functional) user prefe­rences, interfaces of management support systems (MSS) are becoming more important. We develop design guidelines for new MSS interfaces from a new-generation manager perspective. We compile a set of requirements from a literature review and based on a multiple-case study we synthesize five guidelines: (1) use sparklines to present informa­tion at a glance and complement them with tooltips to access details, (2) support eco­nomic value-added concepts as a must-have and be aware that self-service predictive analyses make them more valuable, (3) draw managers' attention to critical events in real-time by sending notifications to their smart devices, (4) to harvest the knowledge of different users, integrate collaboration capabilities into MSS interface designs, (5) align different information media with managers' device selection and do not forget their mobile offline use situations.
Brugada Syndrome Mimicked by Tricyclic Antidepressant Overdose

A 33-year-old man was successfully resuscitated from an out-of-hospital episode of ventricular  brillation. Upon admission, an ECG showed sinus rhythm with a right bundle branch block, prolonged QTc interval of 526 msec, and downsloping ST elevation typical of the Brugada syndrome (panel A). A history of drug overdose was elicited, and the plasma nortriptyline concentration was found to be 476 m g/mL (therapeutic range 50 to 150). Serial ECGs demonstrated gradual normalization of the ECG (panel B). As previously reported with other tricyclic antidepressant drugs, this case demonstrates that an acute overdose of nortriptyline can mimic the Brugada syndrome. Supported in part by a grant from the Japanese Society of Cardiac Pacing and Electrophysiology, and by the Don Nouse Arrhythmia Research Fund.
Tianeptine Influence on Plasmatic Catecholamine Levels and Anxiety Index in Rats Under Variable Chronic Stress After Early Maternal Separation

The aim of this work was to determine the effect of chronic treatment with 5 mg/kg of tianeptine in male adult Wistar rats separated from the mother as neonates and submitted to variable chronic stress, plasma catecholamines, and anxiety. The plus maze test was performed in order to calculate the anxiety index and catecholamine levels were determined by high-pressure liquid chromatography. Both stress and maternal separation elevated catecholamine levels without affecting anxiety. In the maternally separated stress group, tianeptine decreased epinephrine. Anxiety was reduced in the maternally separated unstressed tianeptine group. Also, all groups showed a tendency to lower anxiety index.
Depression treatment patterns among women veterans with cardiovascular conditions or diabetes

The study aimed to examine treatment patterns for depression among women veterans diagnosed with cardiovascular conditions or diabetes. We used longitudinal data from the 2002-2003 merged Veteran Health Administration (VHA) and Medicare files. Chi-square tests and multinomial logistic regression were performed to analyse depression treatment among veteran women with incident depressive episode and one of the following chronic conditions: diabetes or coronary artery disease or hypertension. Overall, 77% received treatment for depression, 54% with only antidepressants, 4% with only psychotherapy, and 19% with both. Multinomial logistic regression revealed that African American women were more likely to be in the no treatment group and were more likely than white women to receive psychotherapy rather than antidepressants. Older women and women with coronary artery disease only were less likely to receive treatment.
Superficial scald, a functional disorder of stored apples. IV. Effect of variety, maturity, oiled wraps and diphenylamine on the concentration of alpha-farnesene in the fruit.

During storage of apples at 1° the concentration of a-farnesene in the ‘coating’ (mainly cuticle) and adjacent cells increased to a maximum and then declined. At the highest maximum farnesene was 15% of the total lipid of the coating. Evidence is presented for a role of a-farnesene in superficial scald. More a-farnesene was found in earlier picked apples and more in the scald-liable Granny Smith than in the scald-resistant Crofton variety. During storage a-farnesene moved from the fruit to the oiled wraps until wraps contained more than twice as much as the fruit. Diphenylamine reduced the production of a-farnesene in later picked apples.
The y134.5 gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells

The yv34.5 gene of herpes simplex virus 1 was previously shown to play a role in viral vPrulence since deletion of the gene reduced by a factor of 4100,000 the capacit of the virus to replicate in the central nervous system and cause mortality in the mouse. Here we show that in the human neuroblastoma cell ling SK-N-SH ofneuronal origin 134.5 null mutants expressed early proteins, viral IQNA, and mRNA of late genes. However, the onset of viral I.NA synthesis triggered complete cessation of incorporation of radioactiyp preursors into proteins. The mutant and wild-type virus replicated and could not be differentiated in cell lines or cell striins of nonneuronal origin. The results indicate that in the absence of the y,34.5 gene' the SK-N-SH neuroblastoma cells triggered a response similar to the programed cell death of neuronal cells induced by metabolic stress. The yi34.5 protein precludes this cell response possibly in order to enable the protein synthesis necessary for viral replication. The most severe and devastating manifestation of herpes simplex virus 1 (HSV-1) infection is encephalitis, which afflicts '4 in 250,000 adults (1). Of considerable interest in connection with this disease are the genes that confer upon the virus the capacity to replicate in the central nervous system (CNS) tissues. Chou et al. (2) reported that a viral gene designated as y134.5 enables the virus to multiply and spread in the CNS of mice even though it is not essential for viral replication in cell culture and in at least some murine tissues tested to date (R. J. Whitley, E. R. Kern, S. Chatterjee, J.C., and B.R., unpublished data). The y134.5 gene is located in the inverted repeats flanking the long component of viral DNA and therefore the gene is present in two copies per genome (4-7) (see Fig. 1). Its location is consistent with previous reports showing that a locus that affected the capacity of the virus to multiply in the CNS tissues mapped at the right end of the long component of HSV DNA in the prototype arrangement (2, 8-11). In the course of studies designed to determine the function of the 'y134.5 gene product, we discovered that infection of cells of neuronal origin with mutants incapable of expressing the y134.5 gene resulted in shutoffofcellular protein synthesis, whereas infection ofcells ofnonneuronal origin with wild-type or mutant viruses resulted in sustained protein synthesis and production of infectious progeny. (Some of the results reported in this article were presented at the 15th Internatiqnal Herpesvirus Workshop, July 7-12, 1991, Asilomar, CA.), MATERIALS AND METHODS Cels. Vero cells originally obtained from the American Type Culture Collection (ATCC) were propagated in Dulbecco's modified Eagle's medium (DME medium) containing a b blVa'c' c a HSV-1(F) I J I
Intra-articular kinematics of the normal glenohumeral joint in the late preparatory phase of throwing: Kaltenborn's rule revisited

A new method to quantify intra-articular relationships between articular surfaces of the glenohumeral joint during discrete poses representing the late preparatory phase of throwing is presented. This method is based on 3D bone reconstructions from medical imaging data processed into finite helical axis parameters. With the shoulder moving in the anatomical planes from 90° abduction and 90° external rotation into the apprehension test pose, the centre of the humeral head posteriorly translated on the glenoid and rotated about a finite helical axis, which was positioned at the joint contact. The data are contrasted with Kaltenborn's convex-concave rule explaining intra-articular kinematics of the glenohumeral joint as a ball-and-socket joint. The data show at all conditions that the glenohumeral joint does not act as a ball-and-socket joint. Consequently, the mobilization techniques used in manual therapy, which are based on this convexconcave rule, should be adapted.
Antidepressant and QT interval prolongation, how should we look at this issue? Focus on citalopram

Introduction: Evidence increasingly points to the potential development of harmful cardiac side effects concomitant with the use of a number of psychotropic drugs, primarily traditional antipsychotics and tricyclic antidepressants. Areas covered: The US Food and Drug Administration announced safety warnings associated with the use of citalopram with QT interval prolongation in 2011 and 2012. This paper explores the clinical background of QT interval prolongation, clinical data related to antidepressants and QT interval prolongation, the clinical implications of safety issues associated with the use of antidepressants and future research directions. Expert opinion: Currently available evidence proposes that citalopram may not be definitely associated with the increase of cardiac mortality, although it should be related with increase of QT prolongation. A firm consensus regarding the cardiac safety issues associated with antidepressants has to be established in near future. Hence, the choice of an individual antidepressant regarding cardiac safety issues should be based on multiple factors; clinicians may need to select the best available antidepressant for each individual based on that patient's vulnerability, the proven efficacy and safety of each agent and a reasonable benefit:risk ratio, based on currently available findings.
Tularemia vaccine study. II. Respiratory challenge.

Previous studies from these laboratories demonstrated that man can readily be infected by intracutaneous inoculation with approximately 10 Pasteurella tularensis organisms (SCHU S4 strain). 1 Prior vaccination with killed Foshay vaccine did not prevent local lesions, but did reduce the incidence of systemic manifestations of infection. Review of accidental laboratory infection indicates that the respiratory route may serve as a portal of entry. 2 Experimental respiratory infections can easily be induced in both vaccinated and nonvaccinated monkeys, and response to therapy is good. 3 This present report describes the response to respiratory challenge with P. tularensis of nonvaccinated volunteers and of volunteers who received either killed vaccine or a viable attenuated vaccine. Materials and Methods Volunteers were inmates of the Ohio State Penitentiary, 21 to 35 years of age. Criteria for selection and conditions of volunteering have been described. 1 Vaccination with Foshay killed tularemia vaccine was conducted as previously
Stomatal Size in Fossil Plants: Evidence for Polyploidy in Majority of Angiosperms

Three published estimates of the frequency of polyploidy in angiosperms (30 to 35 percent, 47 percent, and 70 to 80 percent) were tested by estimating the genome size of extinct woody angiosperms with the use of fossil guard cell size as a proxy for cellular DNA content. The inferred chromosome numbers of these extinct species suggest that seven to nine is the primitive haploid chromosome number of angiosperms and that most angiosperms (approximately 70 percent) have polyploidy in their history.
Effect of magnesium ions and ethylenediamine tetra-acetic acid on the activity of vancomycin against Escherichia coli and Staphylococcus aureus.

SUMMARY When added to logarithmically dividing Encherichia coli, vancomycin caused lysis only when the nutrient medium was deficient in magnesium ions. They did not prevent vancomycin from exerting an inhibitory effect on Staphylococcus aureus growing in the log phase. Ethylenediamine tetra-acetic acid (EDTA) was less inhibitory to E. coli than to Staph. aureus, but in sub-bacteriostatic concentrations it potentiated the activity of sub-inhibitory doses of vancomycin against E. coli. EDTA probably removes some cations in the cell wall, thus facilitating the entry of vancomycin; it does not potentiate the activity of sub-bacteriostatic doses of vancomycin against Staph. aureus.
Integrated Energy Efficient Data Centre Management for Green Cloud Computing - The FP7 GENiC Project Experience

Energy consumed by computation and cooling represents the greatest percentage of the average energy consumed in a data centre. As these two aspects are not always coordinated, energy consumption is not optimised. Data centres lack an integrated system that jointly optimises and controls all the operations in order to reduce energy consumption and increase the usage of renewable sources. GENiC is addressing this through a novel scalable, integrate energy management and control platform for data centre wide optimisation. We have implemented a prototype of the platform together with workload and thermal management algorithms. We evaluate the algorithms in a simulation based model of a real data centre. Results show significant energy savings potential, in some cases up to 40%, by integrating workload and thermal management.
Improved network survivability using multi-threshold adaptive range clustering (M-TRAC) algorithm for energy balancing in wireless sensor networks

Wireless Sensor Networks WSNs have become one of the most prominent areas of research in the field of modern communication systems. But unlike IP based routing, WSNs focus on data centric communication. Thus routing is one of the important issues to be considered for a WSN. As sensor networks are generally deployed in hostile environments, batteries cannot be recharged often. Thus energy conservation is one of the important design parameters for WSNs. Many energy aware routing protocols were proposed in the literature. Cluster based algorithms were proved to be better compared to multi-hop routing. In this paper an attempt is made in proposing a novel cluster based energy efficient routing algorithm for WSNs namely the Multi-Threshold Adaptive Range Clustering M-TRAC algorithm, which incorporates centralized network management with variable thresholds in order to assure a uniform load distribution amongst nodes, thus improving the network lifetime.
Is oral morphine still the first choice opioid for moderate to severe cancer pain? A systematic review within the European Palliative Care Research Collaborative guidelines project

The aim of this systematic review was to evaluate the evidence that oral morphine can be recommended as the first choice opioid in the treatment of moderate to severe cancer pain in updating the European Association for Palliative Care opioid recommendations. A systematic literature review was performed to update the 2007 Cochrane review ‘Oral morphine for cancer pain’. The literature search was conducted on MedLine, EMBASE and Cochrane Central Register of Controlled Trials databases. The search strategy, limited in time (from 1 July 2006 to 31 October 2009), was aimed to be as extensive as possible using both text words and MeSH/EMTREE terms; a hand search of the reference lists of identified papers was also performed. Randomized clinical trials, containing data on efficacy and/or side effects of morphine, were identified. Among the papers retrieved from the cited databases and the Cochrane review, 17 eligible studies, for a total of 2053 patients, and a meta-analysis were selected. These studies do not add significant information to the previous Cochrane review confirming the limitation of efficacy and tolerability data on opioid-naïve and non-selected populations of cancer patients treated with morphine and suggesting that oral morphine, oxycodone and hydromorphone have similar efficacy and toxicity in this patient population.
The Loss of Telomerase Activity in Highly Differentiated CD8+CD28−CD27− T Cells Is Associated with Decreased Akt (Ser473) Phosphorylation1

The enzyme telomerase is essential for maintaining the replicative capacity of memory T cells. Although CD28 costimulatory signals can up-regulate telomerase activity, human CD8+ T cells lose CD28 expression after repeated activation. Nevertheless, telomerase is still inducible in CD8+CD28− T cells. To identify alternative costimulatory pathways that may be involved, we introduced chimeric receptors containing the signaling domains of CD28, CD27, CD137, CD134, and ICOS in series with the CD3 zeta (ζ) chain into primary human CD8+ T cells. Although CD3 ζ-chain signals alone were ineffective, triggering of all the other constructs induced proliferation and telomerase activity. However, not all CD8+CD28− T cells could up-regulate this enzyme. The further fractionation of CD8+CD28− T cells into CD8+CD28− CD27+ and CD8+CD28−CD27− subsets showed that the latter had significantly shorter telomeres and extremely poor telomerase activity. The restoration of CD28 signaling in CD8+CD28−CD27− T cells could not reverse the low telomerase activity that was not due to decreased expression of human telomerase reverse transcriptase, the enzyme catalytic subunit. Instead, the defect was associated with decreased phosphorylation of the kinase Akt, that phosphorylates human telomerase reverse transcriptase to induce telomerase activity. Furthermore, the defective Akt phosphorylation in these cells was specific for the Ser473 but not the Thr308 phosphorylation site of this molecule. Telomerase down-regulation in highly differentiated CD8+CD28−CD27− T cells marks their inexorable progress toward a replicative end stage after activation. This limits the ability of memory CD8+ T cells to be maintained by continuous proliferation in vivo.
P2P Techniques for Decentralized Applications

As an alternative to traditional client-server systems, Peer-to-Peer (P2P) systems provide major advantages in terms of scalability, autonomy and dynamic behavior of peers, and decentralization of control. Thus, they are well suited for large-scale data sharing in distributed environments. Most of the existing P2P approaches for data sharing rely on either structured networks (e.g., DHTs) for efficient indexing, or unstructured networks for ease of deployment, or some combination. However, these approaches have some limitations, such as lack of freedom for data placement in DHTs, and high latency and high network traffic in unstructured networks. To address these limitations, gossip protocols which are easy to deploy and scale well, can be exploited. In this book, we will give an overview of these different P2P techniques and architectures, discuss their trade-offs, and illustrate their use for decentralizing several large-scale data sharing applications. Table of Contents: P2P Overlays, Query Routing, and Gossiping / Content Distribution in P2P Systems / Recommendation Systems / Top-k Query Processing in P2P Systems
Interference alignment in the multi input multi output cellular network systems with incomplete measurement of channel information

This paper explores the problem of interference alignment (IA) in cellular multiple-input multiple-output (MIMO) cellular network systems with incomplete channel information. With regards to the realization of the cellular networks, incomplete channel information obtained from the channel is an important part. As to the significance of the issue, the IA with the accessibility of incomplete channel information on both sides of the receiver and transmitter channels is explored. Consequently, performance criteria such as the rate of inadequate channel are obtained. Finally, by providing simulation, verification issues are expressed in different conditions.
New materials and advances in making electronic skin for interactive robots

Flexible electronics has huge potential to bring revolution in robotics and prosthetics as well as to bring about the next big evolution in electronics industry. In robotics and related applications, it is expected to revolutionise the way with which machines interact with humans, real-world objects and the environment. For example, the conformable electronic or tactile skin on robot’s body, enabled by advances in flexible electronics, will allow safe robotic interaction during physical contact of robot with various objects. Developing a conformable, bendable and stretchable electronic system requires distributing electronics over large non-planar surfaces and movable components. The current research focus in this direction is marked by the use of novel materials or by the smart engineering of the traditional materials to develop new sensors, electronics on substrates that can be wrapped around curved surfaces. Attempts are being made to achieve flexibility/stretchability in e-skin while retaining a reliable operation. This review provides insight into various materials that have been used in the development of flexible electronics primarily for e-skin applications.
CRiSOL: Base de Conocimiento de Opiniones para el Español

In this paper we focus on Spanish polarity classification in a corpus of hotel reviews (COAH) and we introduce a new lexical resource called CRiSOL. This new resource is built on the list of Spanish opinion words iSOL. CRiSOL appends to each word of iSOL the polarity value of the related synset of SentiWordNet. Due to the fact that SentiWordNet is not a Spanish linguistic resource, a Spanish version of WordNet had to be used. The Spanish version of WordNet chosen was Multilingual Central Repository (MCR). An unsupervised classifier has been developed with the aim of assessing the validity of CRiSOL. The results reached by CRiSOL are higher than the ones reached by iSOL and SentiWordNet, so that encourage us to continue this research line.
Improved bamboo algorithm based on hierarchical network model

Bamboo is one structured P2P overlay, that likes others (e.g. Chord, Kademlia, Pastry), organizes peers into a flat overlay network and offers distributed hash table (DHT) functionality. It is very promising for its efficient routing performance. However, one disadvantage impeding the DHT algorithm popularity is the routing information maintenance overhead; it generates considerable network traffic and increases P2P system complexity, especially in a highly dynamic environment. Besides, in this structure, all nodes have identical capabilities and responsibilities and all communication is symmetric. In this paper, taking the node heterogeneity into consideration we propose an improved Bamboo based on hierarchical network model to resolve this problem. Furthermore, the routing tables, lookup service and the procedure of node operations will be carefully discussed.