Miracle-dz/UniFAR-FTUs huggingface dataset:
Phenotypic and molecular genetic characterization indicate no major race‐specific interactions between Xanthomonas translucens pv. graminis and Lolium multiflorum

Bacterial wilt of forage grasses, caused by the pathogen Xanthomonas translucens pv. graminis (Xtg), is a major disease of forage grasses such as Italian ryegrass (Lolium multiflorum). The plant genotype-bacterial isolate interaction was analysed to elucidate the existence of race-specific responses and to assist the identification of plant disease resistance genes. In a greenhouse experiment, 62 selected plant genotypes were artificially inoculated with six different bacterial isolates. Significant differences in resistance were observed among L. multiflorum genotypes (P 0·05) could be observed using linear regression modelling. However, additive main effects and multiplicative interaction effects (ammi) analysis revealed five genotypes which did not cluster close to the origin of the biplot, indicating specific interactions between these genotypes and some bacterial isolates. Simple sequence repeat (SSR) markers were used to identify marker-resistance associations using the same plant genotypes and bacterial isolates. The SSR marker NFA027 located on linkage group (LG) 5 was significantly associated with bacterial wilt resistance across all six bacterial isolates and explained up to 37·4% of the total variance of AUDPC values. Neither the inoculation experiment nor the SSR analyses revealed major host genotype-pathogen isolate interactions, thus suggesting that Xtg resistance, observed so far, is effective across a broad range of different bacterial isolates and plant genotypes.
Restoring mussel beds in highly dynamic environments by lowering environmental stressors

Restoration of coastal ecosystem engineers that trap sediment and dampen waves has proven to be difficult, especially in the wave‐exposed and eroding areas where they are needed the most. Environmental stressors, such as hydrodynamic stress and predation, can only be overcome if transplanted organisms are able to establish self‐facilitating feedbacks. We investigate if the artificial lowering of multiple environmental stressors can be used to give transplanted juveniles the opportunity to form a self‐sustainable system and thereby increase their long‐term survival on wave‐exposed and eroding shores. We designed a large field experiment using juvenile mussels (Mytilus edulis) as model species on a wave‐exposed tidal flat in the Oosterschelde estuary (the Netherlands). We tested if the environmental stress caused by a high predation pressure and wave‐driven dislodgement could be reduced by a combination of artificial structures such as fences (to exclude predatory crabs), attachment substrates (such as coir‐net or oyster shells), and breakwaters. Despite a low overall mussel survival (29%), we found that under strong hydrodynamic conditions, experimental fences and attachment substrates increased the retention of transplanted mussel seed. However, modification of local hydrodynamic conditions using breakwaters did not improve mussel coverage preservation. Overall, this study highlights the potential of using techniques that lower multiple environmental stressors to create a window of opportunity for establishment in highly dynamic ecosystems.
Effect of High-K Dielectric materials on Mobility of Electrons

MOSFET is easier to manufacture than BJT and uses less processing power. To follow the law of the MOORE, in this paper we have adopt the principle of replacing SiO 2 dielectric with high-k materials, but it produces some effects. Here we define the problem of mobility. The mobility degradation is due to Coulombic and Phonon scattering. Improvement considerations for the degradation of mobility were also based. This paper offers information on the mobility using different dielectrics.
Shaking Table Test on a Perforated Buckling-Restrained Steel Plate Shear Wall Structure

ABSTRACT In order to avoid local buckling at the edge of infill plates, perforations were introduced in the buckling-restrained steel plate shear wall (BRW) in this paper. And a shaking table test on a 1/4 scaled, four-storey, perforated BRW structure was performed to investigate seismic behavior of BRW structures. During the test, no failure at the edge of the infill plate was observed. The test structure remained essentially intact till the end of the 1.2 g excitations and the residual deformation of the test structure was negligible. In addition, the fundamental frequency of the test structure decreased only 2% after 1.2 g excitations, indicating that there is no need to repair this perforated BRWs structure. The input energy from earthquake was mainly dissipated in first two storeys, in spite of the maximum drifts of each floors differed little from others, as the interstorey drift of the upper storeys were dominated by the overturning effect of the lower storeys. A finite-element (FE) model of the test structure (donated as BR model) was developed using the shell element provided by ABAQUS/Standard, and numerical values agreed well with the test results. Finally, the seismic behaviors of the BR model and a perforated steel plate shear wall structure model (donated as SP model) were compared to show the discrepancies of those two on overall responses, shear force participating ratios of the infill plate, the stress distribution of the infill plate and the additional influences on boundary columns.
Pengaruh Motivasi Pengguna Media Sosial Terhadap Perilaku Adiksi (Studi Kasus Pada Mahasiswa Telkom University Jurusan Ilmu Komunikasi Angkatan 2018)

Abstrak Salah satu penyebab pengaruhnya perilaku adiksi disebabkan oleh motivasi pengguna media sosial khususnya Instagram yang kini popular di kalangan anak muda. Penelitian ini bertujuan untuk mengetahui pengaruh motivasi pengguna media sosial terhadap perilaku adiksi di lingkungan Telkom University khususnya mahasiswa jurusan Ilmu Komunikasi angkatan 2018 dengan menggunakan regresi linear berganda dan skala Likert, serta menggunakan sampel sebanyak 100 orang. Berdasarkan hasil penelitian, dari keempat dimensi motivasi penggunaan media sosial memperoleh skor sebesar 77.91%, artinya motivasi penggunaan media sosial termasuk kedalam kategori tinggi. Motivasi dalam penggunaan media sosial mempengaruhi perilaku adiksi bermedia sebesar 36.2% sementara sisanya (63.8%) dipengaruhi oleh variable lain yang tidak diukur dalam penelitian ini. Dimensi motivasi penggunaan media sosial yang paling signifikan mempengaruhi perilaku adiksi bermedia adalah dimensi hiburan (0.405) dan dimensi presentasi diri (0.426). Kata kunci: Motivasi pengguna media sosial, perilaku adiksi. Abstract One of the causes of the influence of addiction behavior is caused by the motivation of users of social media, especially Instagram, which is now popular among young people. This study aims to determine the effect of motivation of social media users on addiction behavior in the Telkom University environment especially students of the 2018 Communication Studies department using multiple linear regression and Likert scale, and using a sample of 100 people. Based on the results of the study, from the four dimensions of motivation for the use of social media the score was 77.91%, meaning that the motivation for using social media was included in the high category. Motivation in the use of social media affects media addiction behavior by 36.2% while the rest (63.8%) is influenced by other variables not measured in this study. The most significant dimensions of motivation for the use of social media affecting media addiction behavior are entertainment dimensions (0.405) and self-presentation dimensions (0.426). Keywords: Motivation of social media users, addiction behavior.
From Father Flanagan to Hearing Research: A History of Acoustics Research at Boys Town

Father Edward Flanagan, the actor Spencer Tracy, and the multibillionaire Warren Buffett all played a role in the creation of the Boys Town communication disorders research program. As a result, in the last 40 years, more than 300 articles published in The Journal of the Acoustical Society of America (JASA) and many articles elsewhere, have been authored or coauthored by members of the faculty and staff at the Boys Town National Research Hospital (BTNRH). How did Boys Town, an organization known for work with at-risk children, become an important contributor to hearing and speech research?
Factorial Invariance, Latent Mean Differences of the Panas and Affective Profiles and Its Relation to Social Anxiety in Ecuadorian Sample

Positive (PA) and negative affect (NA) are related with aspects that are part of people’s psychological well-being, and the possibility of combining both dimensions to create four affective profiles, self-fulfilling (high PA and low NA), low affective (low PA and low NA), high affective (high PA and high NA) and self-destructive (low PA and high NA), has recently appeared. The current work aims to validate the short version of the Positive and Negative Affect Schedule (PANAS) in Ecuador, test the existence of the four affective profiles and analyze its relation with social anxiety. The Positive and Negative Affect Schedule for Children and the Social Anxiety Scale for Adolescents was employed in a sample of 1786 Ecuadorian students aged from 15 to 18 years (M = 16.31, SD = 1.01). The factorial invariance of the scale across sex and age groups was proved and latent mean analyses showed that girls and 18-year-old students obtained the highest scores in negative affect. With regard to the affective profiles, the cluster analyses confirmed the existence of the four mentioned profiles, and the self-fulfilling profile obtained the lowest scores in all the dimensions of social anxiety, whereas the self-destructive profile obtained the highest scores.
Biokinetics and repeated exposure in in vitro assays : A detailed study into the behaviour of chlorpromazine and diazepam in different cell systems

The potential risk of compounds is commonly assessed with animal experimentation and extrapolation of these data to assess human health effects. The use of Integrated Testing o Strategies combines different methods, including in vitro tests and in silico methods, to perform risk assessment with less costs and less animal experiments. Although alternatives to animal tests have been developed and validated, research into alternatives for certain toxicological endpoints is yet limited. One of these endpoints is systemic toxicology after repeated dosing. In addition, difficulties arise when extrapolating in vitro data to the in vivo situation. In vitro data can be highly variable and it is difficult to compare nominal concentrations in vitro with doses in vivo. One aspect that is often missing in in vitro assays is information on exposure concentrations. These exposure concentrations are highly influenced by the in vitro biokinetics of the test compound. Therefore, the aim of the work presented in this thesis was to study in vitro biokinetics in different cell systems. This was done for both single as well as repeated exposure studies in vitro. The biokinetic behaviour of chlorpromazine was studied in an intestinal permeability assay, cytotoxicity assays with different cell lines and after repeated exposure in different liver cell systems and a primary neuronal cell system. The biokinetic behaviour of diazepam was studied in a repeated exposure experiment with primary neuronal cells. In all these assays, samples were taken from the medium, cells and well plastic to determine the amount of compound in each of these compartments. In addition, the free concentration of chlorpromazine in the medium was measured by a negligible depletion-solid phase microextraction method which was optimised for this compound. The data presented in this thesis show that by expressing in vitro data based on a nominal concentration one ignores the different processes that can take place in vitro and that could influence the actual exposure concentration. By studying the in vitro biokinetics of CPZ in different cell systems, we found that the compound distributes over the different compartments present in an in vitro system: medium (freely dissolved and protein bound), cells and plastic. Although in some cases reasonably good correlations have already been found between in vitro and in vivo data
Conservation of riparian ecosystems in the United States

Riparian ecosystems include relatively mesic vegetative communities and associated faunas occurring between aquatic and more xeric upland sites. In eastern North America, these ecosystems often occur in broad zones and are referred to as floodplains or bottomlands. In the west, they are conspicuous as narrow belts of vegetation along ephemeral, intermittent, and perennial streams and rivers and are most obvious in steppe, shrubsteppe, and desert regions. Vegetation associated with streams has been referred to as the “aorta of an ecosystem” (Wilson 197932) because of its significance to the perpetuation of water, fish, wildlife, rangeland, and forest resources. Historically, riparian ecosystems have been subjected to both subtle and dramatic perturbations from water management practices (Carothers and Johnson 1975, Curtis and Ripley 1975) (Fig. l), agricultural conversions (Best et al. 1979, Conine et al. 1979), grazing (Cope 1979, Knopf and Cannon 1982), channelization (Barclay 1979, McCall and Knox 1979), and recreational development (Aitchison 1977, Schmidly and Ditton 1979, Johnson and Carothers 1982). Riparian systems represent areas of maximum potential conflict between users of timber, grazing, recreational, water, and wildlife resources (Thomas et al. 1979). Additionally, exotic woody species such as salt cedar (Tumavix pentandra) and Russian olive (Elaeagnus angustifolia) have naturalized extensively within western riparian ecosystems (Robinson 1965, Horton 1977, Olson and Knopf 1986b), displacing native woody species that provide valuable avian habitats but also providing additional habitats for selected species of wildlife (Knopf and Olson 1984, Hunter et al. 1985). Riparian ecosystems have recently attracted much attention, especially relative to the management of public lands in the west. Within the last
The origins of decorated ostrich eggs in the ancient Mediterranean and Middle East

Abstract Decorated ostrich eggs were traded around the Mediterranean during the Bronze and Iron Ages. Research on their origins has focused primarily on decorative techniques and iconography to characterise the producers, workshops and trade routes, thereby equating decorative styles with cultural identities and geographic locations. This is problematic, as craftspeople were mobile and worked in the service of foreign royal patrons. The present study investigates the provenance of ancient ostrich eggs, reconsiders trade patterns via isotopic indicators and characterises decorative techniques in order to assist in the identification of culturally distinct decorative styles or regional preferences.
Carcinoid of the gallbladder in two dogs

ABSTRACT: A carcinoid is a rare neoplasm derived from neuroendocrine cells that may arise in the hepatobiliary system. This report described two cases of carcinoid of the gallbladder in dogs, with emphasis on the clinical, pathological and immunohistochemical aspects. Case 1 was a 10-year-old female Shih Tzu, with a history of prostration and occasional episodes of diarrhea and vomiting. Case 2 was a 10-year-old male Cocker Spaniel, with a history of diarrhea and abdominal pain. Abdominal ultrasonography suggested a neoplasm of the gallbladder in both cases. The dogs underwent cholecystectomy, and 10% formalin-fixed samples were sent for pathological examination. Histologically, a neoplastic proliferation of neuroendocrine cells was observed in the gallbladder submucosa of both cases. Immunohistochemical labeling for neuroendocrine antibodies, such as synaptophysin, neuron-specific enolase and chromogranin A, confirmed the diagnoses. Carcinoid of the gallbladder is a rare neoplasm in dogs, without specific clinical signs, but should be included in the differential diagnosis of lesions that affect this organ.
Electromagnetic–Mechanical Coupling Optimization of an IPM Synchronous Machine with Multi Flux Barriers

In this paper, an interior permanent magnet (IPM) synchronous machine with multiflux barriers is proposed to meet the wide speed regulation application requirements of electric vehicles. Based on the flux barrier characteristic, an electromagnetic–mechanical coupling optimization strategy is employed for the machine design. In order to facilitate the optimization design, the rotor barriers are divided into two optimization zones, the maximum stress zone and the maximum deformation zone. The electromagnetic–mechanical coupling optimization strategy is divided into two stages accordingly. In the first stage, the machine is regarded as a synchronous reluctance machine by ignoring permanent magnets, where the dimensions of the arc-shaped barriers are optimized to achieve a large reluctance torque and small stress. In the second stage, the dimensions of the arc-shaped PMs and the elliptical barrier are optimized with three objectives of minimum torque ripple, minimum flux linkage, and minimum deformation. After machine optimization, the comparison investigations are carried out on the basis of finite-element analysis by considering both the electromagnetic performances and mechanical performances.
An unusually diverse northern biota from the Morrison Formation (Upper Jurassic), Black Hills, Wyoming

The Little Houston Quarry in the Black Hills of Wyoming contains the most diverse vertebrate fauna in the Morrison Formation (Upper Jurassic) north of Como Bluff and the second-most diverse in the entire formation, after Reed’s Quarry 9. The deposit was an occasionally reactivated abandoned river channel, in interbedded green mudstone and laminated green-gray siltstone above a channel sandstone. The dinosaur material is densely distributed and is disarticulated to articulated, with several associated skeletons. The biota contains charophytes, horsetails, a possible seed fern, possible conifers, gastropods, two types of unionoid bivalves, diplostracans (“conchostracans”), a malacostracan, ray-finned fish, lungfish, a frog, salamanders, two types of turtles, rhynchocephalians, a lizard, choristoderes, two types of crocodyliforms, a pterosaur, Allosaurus and several types of small theropods including Tanycolagreus? and probable dromaeosaurids, numerous Camarasaurus and a diplodocine sauropod, a stegosaur, the neornithischian Nanosaurus, and the mammals Docodon, Amblotherium, and a multituberculate. Among these taxa, one of the unionoid bivalves, an atoposaurid crocodyliform, and the species of Amblotherium, which appear to be new and unique to the locality so far. The Docodon material may represent the first occurrence of D. apoxys outside of its type area in Colorado. Additionally, small, unusual theropod tooth types reported here may represent the first Late Jurassic occurrence of cf. Richardoestesia in North America and a possible abelisauroid, respectively.
Exzessive Gewichtszunahme in der Schwangerschaft und die prognostische Bedeutung des Apolipoprotein B

Zusammenfassung Einleitung Exzessive Gewichtszunahme (EGZ) stellt einen Risikofaktor in der Schwangerschaft dar. Da die EGZ ebenso wie Hypertensive Schwangerschaftserkrankungen (HES) und die intrauterine Wachstumsrestriktion (IUGR) mit veränderten Konzentrationen Apolipoprotein B- (ApoB) haltiger Lipoproteine einhergehen, wurde der Hypothese nachgegangen, ob die ApoB-Konzentration im ersten Trimester diese Ereignisse vorhersagen kann. Methoden Von 547 Schwangeren zeigten 95 eine unzureichende, 171 eine empfohlene und 281 eine EGZ. 23 Schwangere wiesen eine HES, 67 ein small for gestational age (SGA) Neugeborenes und sieben eine IUGR auf. Die ApoB-Konzentration wurden mittels ELISA in Serum der 11+0 bis 13+6 SSW bestimmt. Ergebnisse Die mittleren ApoB-Konzentrationen der Patientinnen verschiedener Gewichtszunahme-Gruppen waren nicht signifikant unterschiedlich. Frauen mit Adipositas zeigten höhere ApoB-Konzentrationen als normalgewichtige (p<0,001). Patientinnen mit präexistentem Hypertonus sowie Raucherinnen wiesen erhöhte ApoB-Konzentrationen verglichen mit normotensiven Kontrollen (p=0,0015) und Nichtraucherinnen (p=0,0118) auf. Eine prognostische Bedeutung ließ sich in Bezug auf HES und IUGR/SGA nicht nachweisen. Folgerung Die ApoB-Konzentration im ersten Trimester ist nicht für die Vorhersage einer EGZ oder Schwangerschaftskomplikation geeignet. Bei bestehenden pathologischen Zuständen wie Rauchen, Adipositas und chronischer Hypertonie sind die ApoB-Werte erhöht und könnten in diesen Gruppen zur Pathogenese von Schwangerschaftserkrankungen beitragen.
In silico Stability Analysis and Phosphorylation Induced Structural Simulation of Alpha-synuclein in Parkinson's disease

Alpha-synuclein (α-syn) is the major component of pathologic inclusions that characterizes neurodegenerative disorders such as Parkinson’s disease (PD), dementia with Lewy body disease, and multiple system atrophy. Mutations and phosphorylation of α-syn causes familial PD. Phosphorylation of α-syn at TYR125 and SER129 plays an important role in PD and enhances its partial digestion by calpains leading to its aggregation; however, the exact mechanism is unknown. The present study uses in silico based approach to unravel this obscure mechanism. Phosphorylation of residues Ser-87, Tyr-125 and Ser-129 was performed for both wild-type and reported mutations, viz., A53T, A30P, and E46K. The authors modeled and validated these mutants and also analyzed the energy variation (force fields) to correlate their significance in stability of proteins. Noteworthy implications include changes in stability of proteins after being simulated using NAMD (VMD). The degradation of the protein by proteolytic enzyme calpain leads to the formation of β-sheet-like oligomer which further gives rise to Lewy bodies which is the hallmark of PD.
Enabling Rack-scale Confidential Computing using Heterogeneous Trusted Execution Environment

With its huge real-world demands, large-scale confidential computing still cannot be supported by today’s Trusted Execution Environment (TEE), due to the lack of scalable and effective protection of high-throughput accelerators like GPUs, FPGAs, and TPUs etc. Although attempts have been made recently to extend the CPU-like enclave to GPUs, these solutions require change to the CPU or GPU chips, may introduce new security risks due to the side-channel leaks in CPU-GPU communication and are still under the resource constraint of today’s CPU TEE.To address these problems, we present the first Heterogeneous TEE design that can truly support large-scale compute or data intensive (CDI) computing, without any chip-level change. Our approach, called HETEE, is a device for centralized management of all computing units (e.g., GPUs and other accelerators) of a server rack. It is uniquely designed to work with today’s data centres and clouds, leveraging modern resource pooling technologies to dynamically compartmentalize computing tasks, and enforce strong isolation and reduce TCB through hardware support. More specifically, HETEE utilizes the PCIe ExpressFabric to allocate its accelerators to the server node on the same rack for a non-sensitive CDI task, and move them back into a secure enclave in response to the demand for confidential computing. Our design runs a thin TCB stack for security management on a security controller (SC), while leaving a large set of software (e.g., AI runtime, GPU driver, etc.) to the integrated microservers that operate enclaves. An enclaves is physically isolated from others through hardware and verified by the SC at its inception. Its microserver and computing units are restored to a secure state upon termination.We implemented HETEE on a real hardware system, and evaluated it with popular neural network inference and training tasks. Our evaluations show that HETEE can easily support the CDI tasks on the real-world scale and incurred a maximal throughput overhead of 2.17% for inference and 0.95% for training on ResNet152.