Miracle-dz/UniFAR-FTUs huggingface dataset:
A Secure Data Transmission for Cluster basedWireless Sensor Network Using LEACHProtocol

Secure data transmission is a critical issue for Wireless Sensor Networks (WSNs). Clustering is an effective and practical way to enhance the system performance of WSNs. In recent years, wireless communication due to rapid hardware cost reduction and providing its devices with portability has become one of the most important communication methods in our everyday life. Many people communicate with others through wireless environment almost every day. However, from privacy viewpoint, wireless security is a crucial challenge since messages are delivered to their destinations through the air so hackers can maliciously intercept the messages and decrypt the messages. A Clustering sensor node is an efficient topology and a crucial issue in Wireless Sensor Network (WSN). Clustering is a technique in which small light weight, low cost , low power sensor nodes are grouped in to some clusters. In this paper, propose a security solution for LEACH (Low-Energy Adaptive Clustering Hierarchy), a protocol where clusters are formed dynamically and periodically. A LEACH protocol effective one to reduce and balance the total energy consumption for CWSNs.
Extraction of Image Texture and Color Features: CBIR Techniques

: In modern days with the increase of social networking mediums so many digital images are uploaded every day to access this very large image collection New technology introduced that is the Content Based Image Retrieval which is Image mining system. Due to the enormous increase in image database sizes as well as its vast deployment in various applications, the need for CBIR development arose. The need to find a desired image from a large collection is shared by many professional groups, including journalists, design engineers and art historians. Content-based image retrieval (CBIR) is an important research area for manipulating large amount of image databases and archives. CBIR implements retrieval based on the similarities described in terms of extracted features with more goodness. In this paper, dynamic content-based image search and retrieval is conferred called feature extraction method. The perceptible contents of an image such as texture & color feature extractions are availed in CBIR. CBIR requires feature extraction and computation of similarity. The Haar wavelet transform is used for texture feature extraction, and for color feature extraction use color moments. The distance between the query image features and the database images features is computed. Experiment results reflect the importance of the Haar wavelet transform and color moments in the performance of proposed CBIR method.
A Machine Learning Approach for MRI Brain Tumor Classification

: A new method for the denoising, extraction and tumor detection on MRI images is presented in this paper. MRI images help physicians study and diagnose diseases or tumors present in the brain. This work is focused towards helping the radiologist and physician to have a second opinion on the diagnosis. The ambiguity of Magnetic Resonance (MR) image features is solved in a simpler manner. The MRI image acquired from the machine is subjected to analysis in the work. The real-time data is used for the analysis. Basic preprocessing is performed using various filters for noise removal. The de-noised image is segmented, and the feature extractions are performed. Features are extracted using the wavelet transform. When compared to other methods, the wavelet transform is more suitable for MRI image feature extraction. The features are given to the classifier which uses binary tree support vectors for classification. The classification process is compared with conventional methods.
Evaluation of Temperament and Transportation Stress on Body Composition Traits and Meat Quality in Beef Cattle

Stressors can be psychological (restraint, handling, or novelty) or physical (hunger, thirst, fatigue, injury, or thermal extremes) (Grandin, 1997). Temperament has been associated with stress responsiveness in which higher concentrations of cortisol have been correlated with temperament of cattle (Curley et al., 2006; King et al., 2006). In addition, Smith and Grandin (1999) reported that appropriate handling of cattle and swine, as contrasted with improper or inappropriate handling, can result in improved productivity of live animals; in higher quality of slaughter livestock, carcasses, and cuts; and in greater profitability in the production and packing sectors. Voisinet et al. (1997) determined that feedlot cattle with calm temperaments have higher average daily gains than cattle with excitable temperaments. Additionally, over the past several years real-time ultrasound has provided a means in which to measure carcass traits (i.e., longissimus muscle area, rib fat, and intramuscular fat) in the live animal. For young cattle, quality grade is determined primarily by marbling, and ultrasound can provide an estimation of intramuscular fat which can be related to marbling in the carcass. Lipid deposition is believed to follow a set hierarchal pattern of omental, peripheral, subcutaneous, intermuscular, and intramuscular. However, certainly genetics, sex, health, implantation program, environment, stress, nutrition, and management all impact lipid deposition. Intramuscular fat is one of the last depot sites in beef cattle and also a fat that can be easily mobilized in times of nutrition or environmental stresses. For the past 4 years our research team has focused on elucidating the interactions between disposition and physiological stress on production performance in beef cattle. One aspect of this research involves the evaluation of the combined effects of transportation stress and animal temperament on real-time ultrasound body composition traits (primarily ultrasound intramuscular fat).
Bortezomib in Combination with High-Dose Dexamethasone and Continuous Low-Dose Oral Cyclophosphamide for Relapsed Multiple Myeloma.

Single agent bortezomib treatment yields ≥ partial responses (PR) in 24% of patients with relapsed, refractory multiple myeloma (MM) and 38% of patients who had received 1 – 3 previous therapies. Dexamethasone (DEX) adds to anti-myeloma activity of bortezomib. The present phase II trial was intitiated to study bortezomib combined with DEX and continuous low-dose oral cyclophosphamide (CY). 50 patients with advanced MM were scheduled to receive bortezomib 1.3 mg/m2 IV days 1, 4, 8, and 11 q 3 weeks for 8 cycles in combination with DEX 20 mg PO on the day of bortezomib injection and the day thereafter, and CY 50 mg PO daily; followed by 3 cycles bortezomib 1.3 mg/m2 IV days 1, 8, 15, and 22 q 5 weeks in combination with corresponding DEX and CY schedules. Patient characteristics included median age 63 years; B2M > 3,0 mg/L, 64%; CRP > 3,0 mg/L, 25%; deletion of chromosome 13, 46%; median number of prior regimens, 2 (range 1 – 9), and prior standard therapy > 12 mo, 94 %. 78% of patients had relapsed after high-dose melphalan. The EBMT criteria were used for definition of response. Five patients (10%) achieved a complete response, 33 (66%) a PR, and 6 (12%) a minor response (MR) resulting in an overall response rate (≥MR) of 88%. On an intention-to-treat basis, median event-free survival (EFS) with this combination was 10 months. After a median follow-up of 10 months, median overall survival has not been reached. Notably, chromosome 13 deletion was predictive of a favorable outcome (higher response rate, longer EFS) in this setting. The median number or treatment cycles given was 6. 56% of the patients terminated study treatment prematurely, mainly for disease progression (10%) or adverse events (34%). Grade 4 neutropenia during at least one treatment cycle occurred in one patient (2%), grade 4 thrombocytopenia in 17%; one thrombocytopenic bleeding. Grade 3/4 non-hematologic toxicities requiring dose or schedule modifications included infections (26%), peripheral neuropathy (25%), fatigue (15%), herpes zoster (13%), and cardiovascular events (11%). One patient succumbed to infection without predisposing neutropenia. Bortezomib in combination with DEX and CY appears to be a highly active regimen without increased toxicity compared to a single agent treatment with bortezomib. Maintenance treatment might be required for prolonged EFS.
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SVM Based Multi-Atlas Segmentation with Joint Label Fusion for Alzheimer Disease

segmented and be n atlases. Fi and Si denote the ith warped atlas image and the corresponding warped manual segmentation of this atlas, obtained by performing deformable image Abstract: Multi atlas segmentations are combined using label fusion. Multi atlas segmentation is based on the observation that segmentation strongly correlates with image appearance especially for biomedical image. A test FMRI image can be segmented by referring to atlases, which uses expert-labeled sample images. For segmentation Chan vese model is used to segment many types of images, including some that would be quite difficult to segment in means of "classical" segmentation – i.e., using thresholding or gradient based methods. After warping the atlas to the test image via deformable registration, one can directly transfer labels from the atlas to the test image. Multi-atlas label fusion (MALF) is becoming more accessible to the medical image analysis. This concept has also been applied in computer vision for segmenting natural images. Errors produced by atlas-based segmentation can be attributed to dissimilarity in the structure (e.g., anatomy) and appearance between the atlas and the test image. Support vector machine for non linear data is used for identification of different segment. For labeling test image Anatomical Automated Labeling (AAL) is used. Label fusion strategies, weighted voting with spatially varying weight distributions derived from atlas-target intensity.
INFLUENCE OF ESTRADIOL VALERATE (PROGYNOVA) ON AGED FEMALE ALBINO RATS WITH REFERENCE TO CARBOHYDRATE METABOLITES

The present study was designed to evaluate the efficacy of estradiol valerate on glucose and glycogen in aged female albino rat tissues. Wistar strain albino rats at 20 months age group were administered with estradiol valerate at dose 8mg/Kg body weight/day orally for one week. The glucose and glycogen levels were estimated in young, aged and aged administered with estradiol valerate. The administration revert the glucose levels in ovary, no changes in uterus, and in vagina further depletion of glucose takes place. Aging does not altered glucose levels in heart and liver but estradiol valerate administration slightly increased as estrogens mobilizes glucose levels. After administration glycogen levels were regained in ovary. Elevated glycogen levels in heart have been shown to have cardio protective effects. The liver glycogen storage capacity was diminished in aged rats and elevated by the administration.
Optimized Cooperative LEACH MISO in Wireless Sensor Networks

-- In long range communications of wireless sensor networks (WSN), the most crucial issue is the data reliability. Data reliability is mostly affected by fading. Cooperative MISO (Multiple Input Single Output) is a variant of MIMO (Multiple Input Multiple Output). In this paper we propose an optimized cooperative LEACH (Low-Energy Adaptive Clustering Hierarchy) MISO model where sensors using Alamouti diversity schemes take part in cooperative communication. Sensors are responsible for sensing the environment, data gathering, data compression and cooperative communication. Cluster head cooperates with the nearby sensors to cooperatively communicate with other cluster heads and the sink. The basic aim of this model is to achieve longer life time of WSN along with less energy consumption. This paper also aims at achieving uniform death of the sensors. MIMO helps in long range inter-sensor communication and sensor-sink communication. It has been compared with an existing Cluster Head Cooperative LEACH MIMO model and simulation results prove that the proposed model is more efficient in terms of WSN life-time as well as energy conservation. This paper also represents an optimized model of a previous work which uses mobility.
Toward precision medicine in inflammatory breast cancer

Inflammatory breast cancer (IBC) is an aggressive, although infrequent form of invasive breast cancer. Despite some advances in systemic treatment, even in the early setting, with combined-modality approach being the current recommended standard of care, the prognosis of IBC still remains unfavorable and has not significantly improved over time. Thus, a better understanding of the biology of IBC is eagerly awaited in order to identify possible targets for new drug development. This paper aims to provide an overview on recent data on the molecular and biological features of IBC and on possible targetable pathways. Molecular subtypes of IBC, similarly to other forms of breast cancer, have both therapeutic and prognostic implications. Moreover, few activated pathways have been described in IBC, including angiogenesis, epidermal growth factor receptor (EGFR), Janus kinase/signal transducer of activation (JAK/STAT) signaling and phosphoinositide 3-kinase/Akt/mTOR (PI3K/AKT/mTOR) pathways. However, when tested in clinical trials, agents targeting these pathways have provided only small benefit. Several clinical trials are currently ongoing investigating combination of standard chemotherapeutics, new targeted agents and immunotherapy. Moreover, tumor microenvironment (TME) is likely to play a central role in the disease; targeting the components of the tumor stroma may represent an interesting therapeutic strategy.
Stability indicating atomic absorption, acid-dye spectrophotometric and conductometric methods for the determination of trospium chloride

Three precise, accurate and sensitive methods were developed for the determination of Trospiumchloride in presence of its degradation product (acid and alkaline). Method (A) was atomic absorption spectroscopic (AAS), it is based on the formation of ion-pair precipitate complex (1:1) with ammonium reineckate. The precipitate and the filtrate were used to determine the concentration of the drug by direct and indirect way respectively at 357.9 nm. Method (B) was based on the formation of ion-pair association complex (1:1) with bromocresol purple (BCP), bromophenol blue (BPB) and thymol blue (TB). The coloured products were measured at 412.0±2.0 nm. Method (C) was based on the conductometric determination of Trospium chloride by titration with ammonium reneickateat 20°C and the conductance of the solution is measured as a function of the volume of titrant. Linearity ranges for method (A) were 8.0–120.0 μg/mL and 10.0–120.0 μg/mL for the direct and indirect procedures, respectively. In case of method (B) the linearity ranges were 3.0–20.0 μg/mL for BCP, 2.0–25.0 μg/mL for BPB and 5.0–35.0 μg/mL for TB, while the linearity range was 100.0–1000.0 μg/mL for method (C). Statistical comparison between the results obtained by these methods and the official method.
Latex Agglutination test for the early diagnosis of Cryptococcal meningitis

Cryptococcal infection which may cause meningitis is the most prevalent and common invasive fungal infection. Serodiagnosis is an important adjunct for rapid diagnosis of Cryptococcosis. In the present study, antigen detection using CALAS meridian diagnostic kit was evaluated along with other traditional methods in Nair Hospital, Mumbai.Out of 100 CSF samples, 20% positivity was observed by only culture method, 21% positivity by microscopy and culture method together, while 22% positivity was observed when all the three methods namely culture, microscopy & LAT were used for the testing of CSF. Microscopy, culture and antigen detection tests were well correlated in the study. Cryptococcal antigen detection from CSF was a useful method for an early diagnosis. The immunological diagnosis of Cryptococcal meningitis by CALAS meridian diagnostic kit was rapid and had 92%-95. 5% sensitivity and specificity.
Zinc Sulphate in Azathioprine Induced Hepatotoxicity- An Experimental Study

To investigate azathioprine (AZA) induced hepatotoxicity and possible protective role of Zinc sulphate in rabbit model. Experimental/Analytical study. Animal House, Isra University Hyderabad from July 2010 to November 2011. Eighty rabbits were studied at animal house of Isra University according to inclusion and exclusion criteria. Group 1. Controls (n=20) Rabbits received 0.9% isotonic saline orally Group 2. (n=20) Azathioprine 15 mg/kg. Group 3. (n=20) Azathioprine 15 mg/kg body + Zinc sulphate 1mg/kg orally & Group 4. (n=20) Azathioprine 15 mg/kg body + Zinc sulphate 2 mg/kg orally for four weeks. Blood samples were collected from tail veins. The animals were sacrificed, liver tissue, after fixation in 4% formaldehyde, was embedded in paraffin. Tissue sections of 5μ thickness were subjected to haematoxylin and eosin staining and were assessed by light microscopy. The data was analyzed on Statistix 8.1 using one-way analysis of variance and post hoc test. A p-value of ≤ 0.05 was taken statistically significant. The liver biochemical and histological findings showed significant differences among the controls, AZA and AZA+ Zinc sulphate (p=0.001). Talpur et al., World J. Biol. Med. Science Volume 1 (4), 72-80, 2014, 73 Liver enzymes and histology was deranged significantly in AZA group compared to controls and AZA+ Zinc sulphate (p=0.01). The AZA+ Zinc sulphate showed low rise of liver enzymes and derangement in liver histology when compared to AZA group (p=0.01). The AZA group showed nodular regenerative hyperplasia, veno-occlusinve disease; peliosis hepatis, sinusoidal dilatation, cholestasis, hepatocyte necrosis and perisinusoidal fibrosis. Derangement of hepatocyte cords, hydropic changes with congestion of central venules and sinusoids were observed.Azathioprine induces hepatocellular injury and deranges liver biochemical parameters and Zinc sulphate may be used as an effective protector.
Detection of the Effect of Sharpening of a Color Image Sharpened by Frequency Domain Filters and Identification of Roi using Morphological Mathematical Property

: This study applies sharpening method to satellite images to have better enhancement of image. Image sharpening plays a vital role in image enhancement. Image Enhancement techniques are instigated for making satellite imageries more informative and helping to achieve the goal of image interpretation. We proved that image sharpening for color images using Fast Fourier Transformation is better than by using filters in spatial domain processing. High pass filtering method sharpens the image by attenuating the low frequencies and leaving the high frequencies of the Fourier transform relatively unchanged. The result is obtained by comparing PSNR value of high pass filters with spatial filters . High pass filtering is produces good representative to sharpen the satellite images. The effect of sharpening is detected and the edges of sharpened image is detected to segment the ROI using mathematical morphological property and the performance of edge detectors are evaluated using PSNR value.
Image Segmentation by Using Modified Spatially Constrained Gaussian Mixture Model

—For the probabilistic data analysis generally mixture models, graphical models, Markov random fields and hidden Markov models are used. In the above models for density estimation via Gaussian mixture modeling has been successfully applied to image/video segmentation, speech processing and other fields relevant to clustering analysis and Probability density function (PDF) modeling. Finite Gaussian mixture model is usually used in practice and the selection of number of mixture components is a significant problem in its application. In this paper a modified Gaussian mixture model (MGMM) presented which is based on Markov random field (MRF) and a dependable spatial constraint with EM (Expectation -Maximization) was proposed in order to enhance the segmentation performance. In this method making the M step of the expectation maximization (EM) algorithm cannot be directly applied to the prior distribution for maximization of the log likelihood with respect to the corresponding parameters, the proposed method will results fast and accuracy.
New LMI robust stability criteria of uncertain bidirectional associative memory neural networks

—This paper deals with the uniqueness and stability problem for uncertain bidirectional associative memory (BAM) neural networks with time-varying delays. Based on the Lyapunov-Krasovskii functional approach and free-weighting matrices method, new delay-dependent stability criteria with two classes of system uncertainties are presented in terms of linear matrix inequalities (LMIs). By using the Jensen integral inequality, the obtained results are less conservative than some previous ones. Four examples are given to illustrate the effectiveness of our proposed conditions.
Comparative Evaluation of Radiotherapy with Concurrent Weekly Cisplatin versus Concurrent Daily Erlotinib and Weekly Cisplatin in Locally Advanced Carcinoma Cervix

Background: Erlotinib is an oral epidermal growth factor receptor tyrosine kinase inhibitor. Early phase clinical trials of Erlotinib in combination with cisplatin-based concurrent chemoradiotherapy (CCRT) in locally advanced carcinoma cervix have demonstrated improved antitumor responses with mild toxicity profile; however, the evidence available on this is limited. We prospectively evaluated the efficacy and safety of Erlotinib (150 mg/day) with CCRT in locally advanced carcinoma cervix and compared with standard CRT. Materials and Methods: In this prospective, comparative study, 60 locally advanced carcinoma cervix patients received either Erlotinib (150 mg/day) with CRT or CRT. Treatment CRT included cisplatin 40 mg/m2 intravenously weekly concurrently with external beam radiation followed by intracavitary brachytherapy. Tumor response was calculated as per the WHO criteria. Toxicity and adverse events (AEs) were assessed as per CTCAE v 3. Results: The higher number of patients achieved a complete response in the Erlotinib plus CRT group than the CRT group (28/30, 93.3% vs. 21/30, 70%, P < 0.05), which was statistically significant. The AEs commonly encountered in both the treatment groups were majority of Grade 1/2. A higher incidence of diarrhea and skin reaction was noted in the Erlotinib plus CRT group in comparison CRT, whereas the incidence of nausea and vomiting was higher in the CRT group. No Grades 4 and 5 toxicity was observed in Erlotinib with CRT. Erlotinib was observed to be safe with manageable toxicity profile. Conclusion: Erlotinib 150 mg daily can be safely added to cisplatin-based CCRT in locally advanced carcinoma cervix, to achieve better therapeutic response without potentiating the toxicity.