Miracle-dz/UniFAR-FTUs huggingface dataset:
Conformal invariance of dimer heights on isoradial double graphs

An isoradial graph is a planar graph in which each face is inscribable into a circle of common radius. We study the 2-dimensional perfect matchings on a bipartite isoradial graph, obtained from the union of an isoradial graph and its interior dual graph. Using the isoradial graph to approximate a simply-connected domain bounded by a simple closed curve, by letting the mesh size go to zero, we prove that in the scaling limit, the distribution of height is conformally invariant and converges to a Gaussian free field.
Examples of monitoring and program analysis activities with DeWiz

As parallel program debugging and analysis remain a challenging task and distributed computing infrastructures become more and more important and available nowadays, we have to look for suitable debugging environments to address these requirements. The Debugging Wizard (DeWiz) is introduced as modular and event-graph based approach for monitoring and program analysis activities. Example scenarios are presented to highlight advantages and ease of the use of DeWiz for parallel program visualisation and analysis. Users are able to specify their own program analysis activities by formulating new event graph analysis strategies within the DeWiz framework.
Post-CMOS integration of germanium microstructures

Polycrystalline germanium (poly-Ge) microstructures have been fabricated on standard CMOS wafers. Conventional low pressure chemical vapor deposition (LPCVD) and rapid thermal annealing (RTA) processes were used to achieve low-resistivity (2.3 m/spl Omega/-cm) tensile poly-Ge structural films, with a thermal budget which is compatible with Al (2% Si) metallization. The CMOS circuitry was passivated with low-temperature oxide and amorphous Si; the latter served as a mask against HF during the microstructure release etch. Comb-drive microresonators with integrated trans-resistance amplifiers were used to demonstrate feasibility of this integration strategy. Preliminary measurements on test structures indicate that poly-Ge has promising material properties. Its fracture strength is 2.2 GPa +/- 0.4 GPa, which is comparable to that of poly-Si. Clamped-clamped lateral resonator test structures have quality factors in vacuum as high as /spl sim/30,000. For the process conditions used in this work, the residual stress of as-deposited poly-Ge is -79 MPa (compressive); RTA shifts the stress to 203 MPa (tensile). Deposition and annealing conditions have yet to be optimized to minimize stress.
CONTINUOUS RECONSTRUCTION OF REGULAR GRIDS

LOIC BARTHE RWTH-Aachen, Informatik VIII Ahornstrasse 55, 52074 Aachen, Germany barthe@informatik.rwth-aachen.de BENJAMIN MORA Equipe synthese d’images et realite virtuelle, IRIT-UPS, 118 route de Narbonne, 31072 Toulouse Cedex 4, France mora@irit.fr NEIL DODGSON Rainbow Group-University of Cambridge 15 JJ Thomson Avenue, Cambridge CB3 0FD, UK nad@cl.cam. ac.uk MALCOLM SABIN Numerical Geometry ltd. 26 Abbey Lane, Lode, Cambridge, UK malcolm@geometry.demon. co.uk Our goal is to provide a kernel to allow interactive and accurate modelling of volume objects. As a first step, we present a data structure for three-dimensional fields C
Experimental Therapeutic Strategies for Severe Sepsis

Severe sepsis is the leading cause of mortality in intensive care units. The limited ability of current therapies to reduce sepsis mortality rates has fueled research efforts for the development of novel treatment strategies. Through the close collaboration between clinicians and scientists, progress can be seen in the struggle to develop effective therapeutic approaches for the treatment of sepsis and other immune and inflammatory disorders. Indeed, significant advances in intensive care, such as lung protective mechanical ventilation, improved antibiotics, and superior monitoring of systemic perfusion, are improving patient survival. Nonetheless, specific strategies that target the pathophysiological disorders in sepsis patients are essential to further improve clinical outcomes. This article reviews current clinical management approaches and experimental interventions that target pleiotropic or late‐acting inflammatory mediators like caspases, C5a, MIF, and HMGB1, or the body's endogenous inflammatory control mechanisms such as the cholinergic anti‐inflammatory pathway. These inflammatory mediators and anti‐inflammatory mechanisms, respectively, show significant potential for the development of new experimental therapies for the treatment of severe sepsis and other infectious and inflammatory disorders.
Improving Newton's Method Performance by Parametrization: The Case of the Richards Equation

The nonlinear systems obtained by discretizing degenerate parabolic equations may be hard to solve, especially with Newton's method. In this paper, we apply to Richards equation a strategy that consists in defining a new primary unknown for the continuous equation in order to stabilize Newton's method by parametrizing the graph linking the pressure and the saturation. The resulting form of Richards equation is then discretized thanks to a monotone Finite Volume scheme. We prove the well-posedness of the numerical scheme. Then we show under appropriate non-degeneracy conditions on the parametrization that Newton\^as method converges locally and quadratically. Finally, we provide numerical evidences of the efficiency of our approach.
A relação entre metáforas conceptuais e funções executivas: uma revisão da literatura

Este artigo de revisão integrativa da literatura busca avaliar as evidências recentes acerca da relação entre o desempenho em tarefas ligadas a funções executivas e a compreensão e a produção de metáforas conceptuais. Para tanto, os descritores “metáforas” e “funções executivas”, bem como termos relacionados a este último, foram pesquisados nas bases de dados Pubmed, Scielo e Lilacs. Após seguir critérios de inclusão e de exclusão, foram selecionados sete artigos que trazem debates recentes acerca do tema. A partir dos experimentos descritos nos estudos revisados, verificou-se que há relação entre desempenho em termos de memória de trabalho e de controle inibitório e a compreensão e a produção de metáforas. Ainda, os fatores idade, tamanho de vocabulário e grau de familiaridade com as metáforas são aspectos que modularam as relações entre funcionamento executivo e a compreensão e/ou produção de metáforas.
Multiple predators in the pelagic: modelling behavioural cascades

Summary 1. The behaviour of predators is rarely considered in models of predator‐prey interactions, nor is it common to include multiple predators in models of animal behaviour. 2. We introduce a model of optimal diel vertical migration in zooplankton prey facing predation from two functionally different predators, fish and other zooplankton. Zooplankton predators are themselves subject to predation from larger zooplankton, and all zooplankton face the classical trade-off between increasing growth rate and predation risk from fish towards the surface. Prey are most vulnerable to zooplankton predators at small sizes, but become more visible to fish as they grow. However, by habitat selection prey continuously manage their exposure to different sources of risk. 3. We analyse situations with cascading behavioural interactions of size-structured predator‐prey interactions in the pelagic. In particular, we explore how vertical gradients in growth rates and relative abundance of fish and zooplankton predators affect optimal distribution patterns, growth and mortality schedules. 4. A major model prediction is that prey susceptibility to one functional predator type depends on the abundance of the other predator. Higher abundance of zooplankton predators leads to risk enhancement from fish, minor increases in predation rate from zooplankton and unchanged prey growth rates. Increasing abundance of fish does not alter the risk from zooplankton predators, but reduces growth and development rates. Such asymmetric emergent effects may be common when prey and predators share the same spatial refuge from a common top predator.
Distinguishing Cancerous Liver Cells Using Surface-Enhanced Raman Spectroscopy

Raman spectroscopy has been widely used in biomedical research and clinical diagnostics. It possesses great potential for the analysis of biochemical processes in cell studies. In this article, the surface-enhanced Raman spectroscopy (SERS) of normal and cancerous liver cells incubated with SERS active substrates (gold nanoparticle) was measured using confocal Raman microspectroscopy technology. The chemical components of the cells were analyzed through statistical methods for the SERS spectrum. Both the relative intensity ratio and principal component analysis (PCA) were used for distinguishing the normal liver cells (QSG-7701) from the hepatoma cells (SMMC-7721). The relative intensity ratio of the Raman spectra peaks such as I937/I1209, I1276/I1308, I1342/I1375, and I1402/I1435 was set as the judge boundary, and the sensitivity and the specificity using PCA method were calculated. The results indicated that the surface-enhanced Raman spectrum could provide the chemical information for distinguishing the normal cells from the cancerous liver cells and demonstrated that SERS technology possessed the possible applied potential for the diagnosis of liver cancer.
Circadian clock disruptions and the risk of cancer

Abstract Disrupted circadian rhythms may lead to failures in the control of the cell division cycle and the subsequent malignant cell growth. In order to understand the pathogenesis of cancer more in detail, it is crucial to identify those mechanisms of action which contribute to the loss of control of the cell division cycle. This mini-review focuses on the recent findings concerning the links between the human circadian clock and cancer. Clinical implications concern not only feasible methods for the assessment of the circadian time of an individual or for the determination of the best time for administration of a drug of treatment, but also in the future genetic tests for screening and for planning treatment.
The Phase Retrieval Problem for the Radar Ambiguity Function and the Radar Ambiguity Function for the Phase Retrieval Problem

This talk is based on a joint paper with A. Bonami and G. Garrigós [3] in which the phase retrieval problem for the Radar Ambiguity Function (i.e. the Radar Ambiguity Problem) has been tackled. In particular it was shown that for wide classes of signals, the radar ambiguity problem has a unique solution, up to trivial transformations. In the second part of the talk, we report on ongoing work by the author where the radar ambiguity function is used as a tool to solve other phase retrieval problems.
Mobile Commerce: Promises, Challenges and Research Agenda

Advances in wireless technology increase the number of mobile device users and give pace to the rapid development of e-commerce using these devices. The new type of e-commerce, conducting transactions via mobile terminals, is called mobile commerce. Due to its inherent characteristics such as ubiquity, personalization, flexibility, and dissemination, mobile commerce promises businesses unprecedented market potential, great productivity, and high profitability. This paper presents an overview of mobile commerce development by examining the enabling technologies, the impact of mobile commerce on the business world, and the implications to mobile commerce providers. The paper also provides an agenda for future research in the area.
Grounded theory in corporate social responsibility research

Grounded theory (Gt) is a qualitative methodology, which derives its name from the practice of generating theory from research, which is grounded in data (babchuk 1997). three Gt methodologies have evolved, namely b.G. Glaser’s classic, a.l. strauss and J. corbin’s structured, and k. charmaz’s (1983, 2005, 2006, 2014) social constructivist methodology. the thematic analysis based on Gt is usually called applied thematic analysis (ata) (braun and clarke 2006). as Gt is designed to construct theories that are grounded in the empirical data themselves (Guest et al. 2012) this aspect is also reflected in ata because its process also consists of reading transcripts, identifying and comparing themes, and building theoretical models (boyatzis 1998).
Interest of SiCO low k=4.5 spacer deposited at low temperature (400°C) in the perspective of 3D VLSI integration

For the first time, the interest of a new SiCO low-k spacer material deposited at 400°C is evaluated in the perspective of a 3D VLSI integration. The benefits of SiCO low-k (4.5 vs 7 for SiN) value is preserved throughout the whole integration and translates into a 5% decrease for both effective capacitance and delay of FO3 Ring Oscillators in a 14FDSOI technology. In addition, a NMOS breakdown voltage improvement of 3.5V and a decrease in leakage current of 0.7 decade is demonstrated on thick oxide devices. This electrical performance together with the low temperature deposition makes SiCO a very appealing candidate for 3D VLSI in a CoolCube™ integration scheme.
RNA under attack: Cellular handling of RNA damage

Damage to RNA from ultraviolet light, oxidation, chlorination, nitration, and akylation can include chemical modifications to nucleobases as well as RNA-RNA and RNA-protein crosslinking. In vitro studies have described a range of possible damage products, some of which are supported as physiologically relevant by in vivo observations in normal growth, stress conditions, or disease states. Damage to both messenger RNA and noncoding RNA may have functional consequences, and work has begun to elucidate the role of RNA turnover pathways and specific damage recognition pathways in clearing cells of these damaged RNAs.
Wavelength Tunable Fiber Laser Technology for Optical Coherence Tomography

Wavelength tunable laser has always been the key technology for wavelength-division multiplexing optical communication community, but few have realized that wavelength-swept laser has great potentials in biomedical applications. In this talk, the application of wavelength-swept fiber laser will be especially discussed for Fourier-domain optical coherence tomography source. Various wavelength-swept lasers are investigated using novel fiber-optic wavelength-selecting filters, such as polarization-maintaining fiber and acousto-optic Sagnac loop tunable filters.
İthal Ham Petrol Fiyatları ve Döviz Kuru Arasındaki Eşbütünleşme ve Oynaklık Yayılma Etkisinin İncelenmesi: Türkiye Örneği

Bu calismanin amaci Turkiye’de doviz kurundaki hareketlerin ham petrol fiyatlarindan kisa ve uzun donemde nasil etkilendigini incelemektir. Bu kapsamda 1985-2015 donemine ait aylik ham petrol fiyatlari ve doviz kuru verileri kullanilmistir. Calismada oncelikle ARDL esbutunlesme yaklasimiyla seriler arasindaki uzun ve kisa donem iliskiler analiz edilmis ve seriler arasinda es butunlesme iliskisi tespit edilmistir. Ikinci adimdaki esbutunlesme uzun donem analizine gore ham petrol fiyatlarinin kur oynakligi uzerindeki etkisi negatif ve istatistiki olarak anlamli bulunmustur. Kisa donem analizinde, hata duzeltme teriminin katsayisi istatistiki acidan anlamli ve negatif oldugu gorulmustur. Dolayisiyla degiskenler arasinda ortaya cikan sapmalarin uzun donem denge duzeyine yakinsamakta oldugu soylenebilir. Calismada son olarak Varyansta nedensellik testi kullanilarak seriler arasindaki nedensellik iliskisi incelenmis ve ham petrol fiyatlarindan doviz kurlarina dogru bir oynaklik yayilma etkisinin varligi tespit edilmistir.
LEADERâ€™S SPIRITUALITY AND PSYCHOLOGICAL CAPITAL: A MODERATED MODEL

Leaders can be an effective source of employees’ motivation to proactively respond to market dynamics and cope with the challenging demands of creativity and innovation. Employees who are better at developing psychological capital are more likely to develop the potential for such change-oriented professional demands. Scholars of positive organizational scholarship call for the further investigation of antecedents and outcomes suggesting new connections in order to develop process models for the major construct of psychological capital. Responding to this call and using the theoretical underpinning of dynamic capability this study has proposed a conceptual model suggesting predictive potential of spiritual leadership for psychological capital as a valuable organizational resource which has great motivational proclivity to develop advantageous performance outcomes. The authors further suggest Islamic work ethics of employees as an intervening variable in the capacity of a moderator with diligence and consciousness as main characteristics of Islamic Work Ethics. Hence, it is likely to contribute to the existing literature in the following ways: it addresses gap identified by a meta-analysis for exploring the formative variables for PsyCap only conceptually through its propositions; it suggests future dimensions. An empirical investigation of this study is likely to bring useful information for HR practitioners for guiding selection and recruitment decisions focusing on spiritual values of leaders, nurturing a culture of spiritual leadership and IWEs and developing employees’ psychological capital.
Anatomic Outside-In Reconstruction of the Anterior Cruciate Ligament Using Femoral Fixation with Metallic Interference Screw and Surgical Staples (Agrafe) in the Tibia: An Effective Low-Cost Technique

Background: An anterior cruciate ligament (ACL) rupture is a frequent injury, with short and long-term consequences if left untreated. With a view to benefitting as many patients as possible and preventing future complications, we created a low-cost ligament reconstruction technique. Method: The present article describes an anatomic ACL reconstruction technique. Results: The technique involves single-band reconstruction, using flexors tendon graft, outside-in tunnel perforation, femoral fixation with metal interference screw and surgical staples (Agrafe) in the longitudinal position. Conclusion: We present a simple, easy-to-reproduce technique that, when executed on patients with good bone quality, primarily in the tibia, is effective and inexpensive, favoring its large scale application.
Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat.

BACKGROUND Fabry's disease, an X-linked disorder of lysosomal α-galactosidase deficiency, leads to substrate accumulation in multiple organs. Migalastat, an oral pharmacologic chaperone, stabilizes specific mutant forms of α-galactosidase, increasing enzyme trafficking to lysosomes. METHODS The initial assay of mutant α-galactosidase forms that we used to categorize 67 patients with Fabry's disease for randomization to 6 months of double-blind migalastat or placebo (stage 1), followed by open-label migalastat from 6 to 12 months (stage 2) plus an additional year, had certain limitations. Before unblinding, a new, validated assay showed that 50 of the 67 participants had mutant α-galactosidase forms suitable for targeting by migalastat. The primary end point was the percentage of patients who had a response (≥50% reduction in the number of globotriaosylceramide inclusions per kidney interstitial capillary) at 6 months. We assessed safety along with disease substrates and renal, cardiovascular, and patient-reported outcomes. RESULTS The primary end-point analysis, involving patients with mutant α-galactosidase forms that were suitable or not suitable for migalastat therapy, did not show a significant treatment effect: 13 of 32 patients (41%) who received migalastat and 9 of 32 patients (28%) who received placebo had a response at 6 months (P=0.30). Among patients with suitable mutant α-galactosidase who received migalastat for up to 24 months, the annualized changes from baseline in the estimated glomerular filtration rate (GFR) and measured GFR were -0.30±0.66 and -1.51±1.33 ml per minute per 1.73 m(2) of body-surface area, respectively. The left-ventricular-mass index decreased significantly from baseline (-7.7 g per square meter; 95% confidence interval [CI], -15.4 to -0.01), particularly when left ventricular hypertrophy was present (-18.6 g per square meter; 95% CI, -38.2 to 1.0). The severity of diarrhea, reflux, and indigestion decreased. CONCLUSIONS Among all randomly assigned patients (with mutant α-galactosidase forms that were suitable or not suitable for migalastat therapy), the percentage of patients who had a response at 6 months did not differ significantly between the migalastat group and the placebo group. (Funded by Amicus Therapeutics; ClinicalTrials.gov numbers, NCT00925301 [study AT1001-011] and NCT01458119 [study AT1001-041].).
Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events in patients with peripheral vascular disease.

OBJECTIVES The goal of this study was to prospectively examine the long-term predictive value of brachial-artery endothelial dysfunction for future cardiovascular events. BACKGROUND Brachial-artery endothelial function is impaired in individuals with atherosclerosis and coronary risk factors. The prospective relation between endothelial function determined by brachial-artery ultrasound and long-term cardiovascular risk is unknown. METHODS We examined brachial-artery endothelial function using ultrasound in 199 patients with peripheral arterial disease before elective vascular surgery. Patients were prospectively followed with an average follow-up of 1.2 years after surgery. RESULTS Thirty-five patients had an event during follow-up, including cardiac death (5 patients), myocardial infarction (17 patients), unstable angina (10 patients), or stroke (3 patients). Preoperative endothelium-dependent flow-mediated dilation (FMD) was significantly lower in patients with an event (4.4 +/- 2.8%) compared with those without an event (7.0 +/- 4.9%, p < 0.001), whereas endothelium-independent vasodilation to nitroglycerin was similar in both groups. In a Cox proportional-hazards model, independent predictors of events included age (p = 0.003), more invasive surgery (surgery other than carotid endarterectomy, p = 0.02), and impaired brachial-artery endothelial function (p = 0.002). Risk was approximately nine-fold higher in patients with FMD <8.1% (lower two tertiles) compared with those in the upper tertile (odds ratio 9.5; 95% confidence interval 2.3 to 40). CONCLUSIONS Impaired brachial-artery endothelial function independently predicts long-term cardiovascular events in patients with peripheral arterial disease. The findings suggest that noninvasive assessment of endothelial function using brachial-artery FMD may serve as a surrogate end point for cardiovascular risk.
The hidden threat to HVDC polymeric insulation at design field: Solitonic conduction

While HVDC assets are impetuously expanding worldwide, the design of HVDC polymeric insulation systems still contains unknowns. It has been ascertained that space charge plays a fundamental role in DC insulation reliability because of modifications it may induce in the (Poissonian) electric field distribution, especially when heterocharge is formed during voltage application. Heterocharge (charge close to an electrode of opposite polarity to that of the electrode) can increase the electric field at the interface between electrode and polymer, thereby enhancing injection from the electrode. This can cause so large a field concentration as to increase the conductivity abruptly and lead to insulation failure due to the electrical discharge process called, usually, thermal instability breakdown [1], [2].