Miracle-dz/UniFAR-FTUs huggingface dataset:
Una Nueva Alternativa a Mininet: Emulación de una Red Definida por Software usando VNX

Resumen — Las Redes Definidas por Software (SDN) han introducido un cambio de paradigma en el control y gestion de las comunicaciones, permitiendo el control centralizado de una red desde un dispositivo externo conocido como controlador. Para ello, SDN propone el desacoplamiento del plano de control del plano de datos, estableciendo la comunicacion a traves de un protocolo, el mas conocido OpenFlow. La herramienta mas utilizada para experimentacion con SDN es el emulador Mininet. No obstante, producto de un proyecto de investigacion emprendido por la Universidad Politecnica de Madrid, se ha desarrollado otra herramienta que proporciona soporte para el protocolo OpenFlow, conocida como Virtual Networks over linuX (VNX). En este trabajo se presenta un escenario de red virtual implementado en primera instancia con Mininet y posteriormente con VNX, con el objetivo de contrastar ambas herramientas. Finalmente, se puede constatar que ambas herramientas tienen un desempeno similar, convirtiendose la integracion de VNX y OpenFlow en una nueva opcion para experimentacion con SDN. Palabras clave - SDN; virtualizacion; OpenFlow; Mininet; VNX
The Hopkins Lupus Pregnancy Center: 1987–1991 Update

ABSTRACT: The course of pregnancy in patients with systemic lupus erythematosus is not known. The Hopkins Lupus Pregnancy Center has followed 64 patients (74 pregnancies) prospectively since 1987. Patients are seen monthly and clinical and pregnancy‐related data collected, with particular emphasis on the occurrence of lupus flare. Flare rate during pregnancy was 1.63 per person‐year, compared to 0.64‐0.65 after delivery or in non‐pregnant patients. Flare did not influence pregnancy outcome. Low serum C3 or C4 and high anticardiolipin antibody predicted pregnancy loss, and prednisone dose, aspirin use, diastolic second trimester blood pressure, C3 at first visit, and race predicted preterm birth. Maternal flare and preterm birth are important risks in lupus pregnancy. The latter can be predicted from maternal pregnancy data.
A Prospective Evaluation of Pulmonary Function in Patients With Adolescent Idiopathic Scoliosis Relative to the Surgical Approach Used for Spinal Arthrodesis

Study Design. A prospective evaluation of pulmonary function in patients with adolescent idiopathic scoliosis undergoing surgical correction. Objectives. 1) To evaluate prospectively, at regular intervals, the changes in pulmonary function after surgical arthrodesis of primary thoracic and double primary thoracic–lumbar (double major) types of adolescent idiopathic scoliosis in a homogeneous population; 2) to compare the changes in pulmonary function after surgical correction relative to the surgical approach used for spinal arthrodesis; and 3) to determine if short- to midterm morbidity with respect to pulmonary function is associated with the type of surgical approach used for spinal arthrodesis. Summary of Background Data. The effect of surgical correction on the pulmonary function of patients with adolescent idiopathic scoliosis is controversial. Studies have shown improvement, decline, or no change in pulmonary function after surgical correction of idiopathic scoliosis. Methods. Ninety-eight patients with adolescent idiopathic scoliosis undergoing surgical treatment at the authors’ institution were prospectively evaluated with pulmonary function tests assessing volume (forced vital capacity and total lung capacity) and flow (forced expiratory volume in 1 second). Pulmonary functions were evaluated before surgery and after surgery at 3 months, 1 year, 2 years, and at the final follow-up visit. All patients were divided into four groups depending on the surgical approach used for spinal fusion: Group 1 (n = 47) underwent a posterior spinal fusion with iliac crest bone graft; Group 2 (n = 33) underwent a posterior spinal fusion with rib resection thoracoplasty; Group 3 (n = 7) underwent an anterior spinal fusion with a rib resection thoracotomy; and Group 4 (n = 11) underwent a combined anterior and posterior spinal fusion with autogenous rib and iliac crest graft used, respectively. Results. Patients in Group 1 had improved pulmonary function values at 3 months after surgery, whereas patients in Groups 2, 3, and 4 showed a decline at 3 months after surgery. Two years after surgery, Group 1 had significantly improved pulmonary function values (P < 0.0001), whereas the pulmonary function values of patients in Groups 2, 3, and 4 had returned to preoperative values. Conclusions. 1) Patients with chest cage disruption during surgical treatment showed a decline in pulmonary function at 3 months after surgery. 2) In contrast, patients without chest cage disruption showed an improvement in pulmonary function at 3 months after surgery. 3) Irrespective of the surgical approach used for spinal arthrodesis, postoperative pulmonary function tests (absolute values) returned to preoperative values at 2 years after surgery. 4) Patients who had no chest cage disruption experienced a significantly greater improvement in two of their pulmonary function values at 2 years after surgery than patients with chest cage disruption.
Robust H∞ control for uncertain stochastic systems with state delay

This note deals with the problems of robust stochastic stabilization and robust H ∞ control for uncertain stochastic systems with a time-varying delay in the state. The parameter uncertainties are assumed to be time-varying norm-bounded appearing in both the state and input matrices. The purpose of the robust stochastic stabilization problem is the design of a memoryless state feedback controller such that the closed-loop system is mean-square asymptotically stable for all admissible uncertainties. In the robust H ∞ control problem, in addition to the mean-square asymptotic stability requirement, a prescribed H ∞ performance is required to be achieved. In terms of a linear matrix inequality, sufficient conditions for the solvability of these problems are proposed respectively; the expressions of desired state feedback controllers are given. An example illustrating the proposed approach is provided.
A Review of Measures of Disclosure Outcomes in the IS Privacy Literature

For twenty years, Information Systems (IS) researchers investigated privacy attitudes and disclosure outcomes, yet a full understanding of the privacy disclosure relationship has not been reached. In the current study, we argue that the lack of consensus regarding the privacy-disclosure relationship may stem, at least in part, from methodological shortcomings. We contend that variations in disclosure measurement practices may be responsible for ambiguous findings in the accumulated IS privacy research. We provide a preliminary review of the IS privacy literature from which we aim to build an initial foundation for recommendations regarding measures of disclosure outcomes. We identify four widely used measures of disclosure outcomes (i.e. intentional, breadth of, retrospective self-reports of, and actual disclosure) and discuss their methodological concerns. We conclude with a brief discussion on the methodology for the full review and recommendation for future research.
Smoking and polymorphisms of fucosyltransferase gene Le affect success of H. pylori eradication with lansoprazole, amoxicillin, and clarithromycin

Identification of factors influencing success of Helicobacter pylori (HP) eradication is important for clinical practice. We have prospectively conducted an HP eradication study in the Aichi Cancer Center with a total of 142 patients available for analysis. The overall success rate was 61·3% (95% confidence interval 52·7–69·3%). Smoking during the medication for eradication significantly decreased the success rate (42·9%), whereas smoking cessation during the treatment was associated with a similar rate as for non-smokers (66·7%). We also examined links between an eradication outcome and polymorphisms of Le, Se, IL1A, IL1B, IL1RN and MPO genes, but with one exception none showed any association. The non-functional le allele of Le polymorphisms, leading to decreased expression of Leb antigen to which HP attaches with adhesin, showed a beneficial effect for success. Although further clarification is necessary, our study indicated that smoking cessation and Le gene polymorphisms may affect the success rate of HP eradication.
Frailty modelling for risk analysis in network security and survivability

The common usage of the term frailty, which literally means the condition (quality) of being frail or a fault, may be too ambiguous to be very useful for characterising network security. Nevertheless, the mathematical concept of frailty, which originated in the study of aging and demography, may offer a powerful approach for analysing the risks in network security and survivability. This is because network security analysis is essentially a risk analysis problem, and identifying risks, especially those that are uncertain, latent, unobserved or unobservable (UUUR) (Ma, 2008), and further analysing the potential dependence between those risks are two critical challenges for risk analysis in any field. Frailty modelling excels in addressing these two challenges. When it is integrated with dynamic hybrid fault models (DHF) and extended evolutionary game theory (EEGT) (Ma and Krings, 2011), frailty modelling should provide powerful approaches for analysing risks in network security and survivability.
Residual Events during Use of CPAP: Prevalence, Predictors, and Detection Accuracy.

STUDY OBJECTIVES To assess the frequency, severity, and determinants of residual respiratory events during continuous positive airway therapy (CPAP) for obstructive sleep apnea (OSA) as determined by device output. METHODS Subjects were consecutive OSA patients at an American Academy of Sleep Medicine accredited multidisciplinary sleep center. Inclusion criteria included CPAP use for a minimum of 3 months, and a minimum nightly use of 4 hours. Compliance metrics and waveform data from 217 subjects were analyzed retrospectively. Events were scored manually when there was a clear reduction of amplitude (≥ 30%) or flow-limitation with 2-3 larger recovery breaths. Automatically detected versus manually scored events were subjected to statistical analyses included Bland-Altman plots, correlation coefficients, and logistic regression exploring predictors of residual events. RESULTS The mean patient age was 54.7 ± 14.2 years; 63% were males. All patients had a primary diagnosis of obstructive sleep apnea, 26% defined as complex sleep apnea. Residual flow measurement based apnea-hypopnea index (AHIFLOW) > 5, 10, and 15/h was seen in 32.3%, 9.7%, and 1.8% vs. 60.8%, 23%, and 7.8% of subjects based on automated vs. manual scoring of waveform data. Automatically detected versus manually scored average AHIFLOW was 4.4 ± 3.8 vs. 7.3 ± 5.1 per hour. In a logistic regression analysis, the only predictors for a manual AHIFLOW > 5/h were the absolute central apnea index (CAI), (odds ratio [OR]: 1.5, p: 0.01, CI: 1.1-2.0), or using a CAI threshold of 5/h of sleep (OR: 5.0, p: < 0.001, CI: 2.2-13.8). For AHIFLOW > 10/h, the OR was 1.14, p: 0.03 (CI: 1.1-1.3) per every CAI unit of 1/hour. CONCLUSIONS Residual respiratory events are common during CPAP treatment, may be missed by automated device detection and predicted by a high central apnea index on the baseline diagnostic study. Direct visualization of flow data is generally available and improves detection.
Low-cost multi-hypothesis motion compensation for video coding

In conventional motion compensation, prediction block is related only with one motion vector for P frame. Multihypothesis motion compensation (MHMC) is proposed to improve the prediction performance of conventional motion compensation. However, multiple motion vectors have to be searched and coded for MHMC. In this paper, we propose a new low-cost multi-hypothesis motion compensation (LMHMC) scheme. In LMHMC, a block can be predicted from multiple-hypothesis with only one motion vector to be searched and coded into bit-stream, other motion vectors are predicted from motion vectors of neighboring blocks, and so both the encoding complexity and bit-rate of MHMC can be saved by our proposed LMHMC. By adding LMHMC as an additional mode in MPEG internet video coding (IVC) platform, the B-D rate saving is up to 10%, and the average B-D rate saving is close to 5% in Low Delay configure. We also compare the performance between MHMC and LMHMC in IVC platform, the performance of MHMC is improved about 2% on average by LMHMC.
Analysis of the influential factors of service recovery satisfaction in telecommunications industry

Based on service recovery theory, taking the customers of China Mobile, one of the telecom operators in China, as the object of research, this research empirically studies the influential factors of service recovery satisfaction in telecommunications industry. A hypotheses model is established with four dimensions of influential factors of service recovery satisfaction: apology, communication, feedback, and compensation. Through comparative study, we determined respectively the influential factors of service recovery satisfaction in substantial channel (business halls) of China Mobile and in non-substantial channel (customer service hotline 10086), and investigated the differences of the factors in two channels. The results showed that our research conclusion has important practice significance to customer retention of China Mobile, and reference significance to customer retention of other telecom operators in China as well.
2 0 O ct 2 01 2 Tradeoffs between Settling Time and Jitter in Phase Locked Loops

In most PLL architectures, trade-off exists between settling time and jitter performance, which is ignored during Figure of Merit calculation. This work derives a new Figure of Merit for PLL, which has settling time as added performance parameter, along with jitter and power. Here, the trade-off between settling time and jitter is analyzed theoretically, and with behavioral simulations for (i) linear Time-to-Digital based PLL (ii) non-linear Bang-Bang Phase Detector based PLL (iii) Hybrid PLL with adaptive gain, to obtain settling time vs. jitter re lation, based on which commonly used Figure of Merit is modified. To understand trade-off relation between settling time and ji tter for Bang-Bang Phase Detector based PLL, this work also derives settling time equation for non-linear PLL, by using recursive time-domain equations. I. I NTRODUCTION Phase Locked Loops, used in various applications, are required to generate frequency with low power consumption, within low settling time and reduced spurious tones. But, in most PLL architectures, the trade-off existing between jit ter, lock time and power does not allow all PLL performance parameters to be optimized simultaneously. Figure of Merit (FoM) defined in [1], which is commonly used to benchmark PLL performance, does not include effect of increase in settling time, while reducing loop gain to red uce jitter, as shown in Eqn. (1).
ENDOSCOPIC SUBMUCOSAL DISSECTION FOR LARGE COLORECTAL TUMORS USING A CROSS‐COUNTER TECHNIQUE AND A NOVEL LARGE‐DIAMETER BALLOON OVERTUBE

Background and Aim: Endoscopic submucosal dissection (ESD) in early gastric cancer (EGC), which provides a higher complete resection rate than conventional endoscopic mucosal resection (EMR), has rapidly come into widespread use. However, colorectal ESD is not widely used because of its technical difficulty and complications such as perforation, and the procedure time is longer than that of conventional EMR. Development of safer and more reliable devices as well as technique modifications are therefore required. The aim of our study is to compare safety and efficacy of a new traction method, the cross‐counter technique, for large colorectal tumors combined with a balloon overtube.
Compositional Dataflow Via Abstract Transition Systems

Despite decades of research and development of dataflow analyses within dozens of different compiler infrastructures, analysis of real programs is intractable in practice. The reason is that although a single research group is equipped to model a single well-defined aspect of application behavior, application developers use a very wide range of abstractions and coding techniques within a single application. Since to analyze even a single application all of its complexities must be modeled, researchers must combine analyses from multiple groups into comprehensive analysis frameworks such as OpenAnalysis or LLVM. Analysis composition is expensive in practice, requiring development effort that is quadratic in the number of analyses as well as tight inter-group coordination to maintain consistent APIs to each other’s symbolic abstractions. This paper proposes an approach to building compiler analysis frameworks that simplifies the composition of independently-developed analyses. It formalizes the operation of dataflow analyses in a way that simplifies reasoning about various types of analysis composition. Further, it defines a portable abstraction that can represent the results of many real analyses, making it possible for different analyses to leverage each other’s results with no knowledge of their APIs or internal abstractions and without any coordination between the groups that developed them. We have developed the Fuse compositional analysis framework based on this abstraction, and integrated it in the ROSE [15] compilation system. Our experience is that this approach greatly simplifies composition of program analyses, making it easy to tailor different combinations of program analyses to different input programs.
Replacement therapy in Addison’s disease

Addison’s disease or primary adrenal insufficiency is a rare disease, which is usually caused by autoimmune destruction of the adrenal cortex. The clinical picture is caused by deficiency of cortisol and aldosterone. These deficiencies are accompanied by adrenal androgen depletion of yet unknown significance. The current therapy is the replacement of glucocorticoids and mineralocorticoids, but the available drugs do not restore the normal diurnal variations in serum hormone levels. The clinical consequences of the grossly unphysiological replacement therapy are largely unknown. Many patients with Addison’s disease on standard replacement therapy complain of fatigue, weariness, and reduced stress tolerance. One particular concern has been negative effects on both bone metabolism due to over-replacement of glucocorticoids and androgen depletion. This review discusses the evidence for the current drug and dosage recommendations. Current recommended daily starting dose for hydrocortisone and cortisone acetate are 20 and 25 mg, respectively, divided into two or preferably three doses. The mineralocorticoid depletion should be treated with fludrocortisone 0.05 – 0.2 mg/day. Replacement of dehydroepiandrosterone 20 – 50 mg has been advocated in adrenal failure, but the evidence for benefit is weak.
RE: Kesik et al: melatonin ameliorates doxorubicin-induced skin necrosis in rats.

To the Editor: Iwas surprised to read the publication, which in my opinion has several inaccuracies. In the worst case, it may lead to inappropriate treatment of patients with extravasation of anthracyclines. The authors state that doxorubicin is one of the most extravasated drugs. This is hardly the case. Extravasation of doxorubicin has often been described in the literature because the outcome of untreated extravasation may be devastating due to its severe vesicant properties. This does not directly reflect the incidence of doxorubicin extravasation. Actually, due to thorough precautions during infusions, the incidence of anthracycline extravasation is probably much lower than that of many other drugs. The authors also state that “Although DMSO and dexrazoxane are 2 promising antidotes . new agents are required with clear evidence of efficacy. ” This is the only mention of dexrazoxane, which for some years has been a gold standard in clinical practice due to its high efficacy in preventing ulcers. The efficacy has been demonstrated in numerous preclinical experiments 8 and in clinical studies during the last decade. The rat experiments call for comments. They were carried out with injection in the panniculus carnosus. In that case, the experiments do not mimic a clinical extravasation. Instead injections should have been made beneath the panniculus. Moreover, intralesional injection of DMSO is not appropriate. Both experimentally and clinically, DMSO should be administered topically. As a consequence, the treatment arms cannot be directly compared. It is also doubtful that experiments using such a high dose of melatonin are clinically relevant at all. Most important, a single ulcer measurement on day 14 is not at all a sufficient parameter to describe the vesicant properties of a substance or to evaluate the efficacy of potential treatment modalities. The frequency of ulcers, as well as their sizes and the durations are absolutely essential parameters that should be taken into account. Regarding the interpretation of the data: The ulcer sizes in the rats were very small (24–54 square mm) and the measurements were therefore hardly reproducible. Also, the sample sizes were too small in numbers for meaningful statistics. Finally, the conclusion regarding the beneficial effect of combining melatonin and DMSO was highly speculative.
Relación del nivel de sintomatología de estrés laboral y de fatiga en trabajadores de una empresa metalmecánica de la ciudad de Bogotá en 2018

Introduccion: Hoy dia la fatiga y el estres son fenomenos cada vez mas comunes entre los trabajadores a nivel mundial. Ojetivo: Relacionar el nivel de sintomatologia de estres y fatiga en trabajadores de una empresa metalmecanica de la ciudad de Bogota durante el 2018. Materiales y metodos: Se realizo un estudio de corte transversal en 186 trabajadores de una empresa metalmecanica de la cuidad de Bogota. Los instrumentos que se aplicaron fueron: Cuestionario para la Evaluacion del Estres, Tercera Version del Ministerio de Trabajo – Colombia y el Cuestionario para la Evaluacion del Estado General de Fatiga (CIS 20, por sus siglas en ingles). Se realizo una relacion entre las variables de estres y fatiga con pruebas de asociacion Ji-cuadrado de independencia, utilizo el coeficiente de correlacion no parametrica de Spearman y el modelo de regresion multivariable de Cox de tiempo fijo constante para medir los niveles de riesgo de fatiga y estres ajustado a las variables potencialmente confusoras (p<0,05). Resultados: El 23,65% de los trabajadores resulto con niveles de fatiga alto y de estres muy alto, siendo las mujeres quienes presentaron mayores niveles de fatiga (54,9%). La experiencia subjetiva de fatiga se correlaciono de forma directa con los sintomas intelectuales y laborales (r=0,510, p<0,05), sintomas fisiologicos (r=0,501, p<0,05) y psicoemocionales (r=0,449, p<0,05) de estres, mostrando una asociacion entre el estres laboral y la sensacion de fatiga. Se encontro la relacion entre estres y fatiga (RP=2.23, IC 95%:1,12, 4,45, p=0,021) ajustado por variables confusoras (sexo, edad, horas de sueno, trabajo en equipo, entre otros). Conclusion: Se hallo que el nivel de estres es un precursor del nivel de fatiga en los trabajadores de la empresa metalmecanica del estudio. Se recomienda disminuir la exposicion a los estimulos estresores como las demandas excesivas, trabajo repetitivo, entre otros, asi como fortalecer y entrenar a los trabajadores en estrategias de afrontamiento, manejo adecuado del estres y tecnicas de relajacion, manejo del tiempo y asertividad. Asi mismo, para la disminucion de los niveles de fatiga se deben realizar campanas para mejorar la higiene del sueno, fomentar el trabajo en equipo y mejorar el ambiente del trabajo.