Miracle-dz/UniFAR-FTUs huggingface dataset:
Computational structural and functional genomics and transcriptomics 23 Chapter # PREDICTION OF INTERFERON-INDUCIBLE GENES IN HUMAN GENOME

Motivation: Application of the methods of computer-assisted genome annotation coupled with large-scale experimental studies may be helpful in determining possible functions of numerous unstudied genes. The search for interferon-inducible genes is of particular interest. As known, interferons modulate the work of the immune system: they exert antiviral, antibacterial, and antitumoral effect. Although the system of interferons is being actively studied during several dozens years, the mechanisms of its functioning are still not clear in many respects. Results: By using the methods developed for recognition of interferon-inducible genes, an analysis of DNA sequences of more than 2000 genes within the length limits from -1000 to +1000 bp relatively transcription start was performed. We have detected 78 genes that could be interferon-inducible with high probability and could participate in supporting some interferon’s functions. Availability: The list of predicted interferon-inducible human genes obtained in the course of the work considered is available at http://wwwmgs.bionet. nsc.ru/mgs/papers/ ananko/iig-trrd/ISG_predicted. html.
A Novel Mapping Method Concerning Low Power on NoC

NoC is an important aspect on the research of the integrated circuit. Low-power NoC is one of the key technologies to promote the applications of NoC. This paper proposes a novel NoC mapping algorithm on how to reduce the communication power. The method can get a better performance by improved max-min ant algorithm, updating the pheromone, and optimizing the weight coefficients and the state transition rules. The experimental result shows that the proposed method can reduce the power consumption effectively during the mapping process and has a good convergence which can accelerate the search process and avoid the stagnation with the compared method.
Reducing Hospitalisation and Antibiotic Use in Suspected Early Neonatal Sepsis through Serial Measurements of C-reactive Proteins

Received July 29, 2003 Abstract Objective: To evaluate whether a standard practice of serial measurements of C-reactive protein (CRP) would reduce the duration of hospitalisation and antibiotic use in newborn infants with birth weight 2.2 kg or more and having clinical features of suspected early neonatal sepsis. Study design: This is a retrospective observational study comparing two groups of newborns with birth weight 2.2 kg or more managed for suspected early neonatal sepsis before and after adoption of a clinical protocol of measuring two serial CRP to guide stopping antibiotics in 1999. The protocol involved checking the first CRP 8 to 16 hours after the initial evaluation and the second CRP one day after the first one. A cut-off value of less than 10 mg/L for the serial CRP was used as a guide to stop the antibiotics. The mortality, duration of hospitalisation and antibiotics of 76 infants managed in 2000 were compared to those of a group of 80 infants in 1998. Results: One infant in the study group died but the death was unrelated to sepsis. The median hospital stay was shorter in the study group (7.0 vs 8.0 days, p=0.03). The median duration of antibiotics was also shorter in the study group (3.0 vs 7.0 days, p<0.005). Three infants (3.9%) in the study group and none in the control group required repeated sepsis evaluation and new antibiotics within one week of cessation of the initial antibiotics (no statistical significance). No infants in either group were readmitted within one week of discharge. Conclusion: After applying a protocol of measuring C-reactive protein serially in the management of suspected early neonatal sepsis, the duration of hospitalisation and antibiotic use may be reduced for infants with birth weight 2.2 kg or more.
Title : Incidence rates , correlates , and prognosis of electrocardiographic P-wave abnormalities – a nationwide population-based study

– a nationwide population-based study Authors: Arttu O. Lehtonen MD , , Ville L. Langén MD , , , Pauli J. Puukka MSocSc , Mika Kähönen MD PhD , Markku S. Nieminen MD PhD , Antti M. Jula MD PhD , , Teemu J. Niiranen MD PhD , Affiliations: a) Department of Health, National Institute for Health and Welfare, Turku, Finland; b) Department of Geriatrics, Turku City Hospital and University of Turku, Turku, Finland; c) Heart Centre; Turku University Central Hospital, Turku, Finland; d) Division of Medicine, Turku University Central Hospital, Turku, Finland; e) Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland; f) Division of Cardiology, Heart and Lung Centre, Helsinki University Central Hospital, Helsinki, Finland; g) Framingham Heart Study, Framingham, MA, USA
Why is a moderate constructivist approach necessary to analyse Europeanization of foreign, security and defence policies?

Europeanization refers to the impact of the European Union polity and policymaking on the national level. This article argues that a moderate (modernist) constructivist approach is necessary to analyse Europeanization of foreign, security and defence policies of EU member states. This is because this approach attributes constitutive and transformative roles to the social and ideational factors that emerge as a result of interaction in institutions. Furthermore, the intergovernmental and consensual nature of the foreign, security and defence policy-making within the EU do not lead to adaptation to rules, regulations and directives as tangible as the economic aspects of integration.
PowerSearch: Augmenting mobile phone search through personalization

Cell phone has become a fundamental element of people’s life. People use it to call each other, browse websites, send text messages, etc. Among all the functionalities, the most important and frequently used is the search functionality. Based on ComScore, in July 2008, Google was estimated to host 235 millions searches per day. However, unlike the search on desktop, the search on cell phone has one critical constrain: battery. Cell phone performing a normal Google search, the battery drains very fast. The reason is that when sending a query to and fetching the results from Google, cell phone keeps communicating to the website through networks such as WiFi and 3G. Yet, due to the limited bandwidth of the network and the large amount of the results, the time of communication will be very long. As a result, the battery dies very quickly. In order to prevent this fast drain of battery, a new program is proposed to personalize the search criteria and fetch the most precise and personalized results, instead of all the results, from the web. Because only a few results are fetched, cell phone will not be communicating with the Internet. Hence, the battery will not die very fast. The program can increase the energy-efficiency of the battery and, thus, lengthen the running time of the cell phone.
Perceptions and Participation: Mistaken Beliefs, Encouragement Designs, and Demand for Index Insurance.

Index insurance is an alternative to crop insurance that bases payouts on a variable that is highly correlated with income but beyond the control of individual households, such as rainfall, temperature, or area-yields (i.e., output per hectare in a large area). Index insurance offers risk protection while avoiding the incentive problems that plague traditional crop insurance, and as a result is seen by many as a promising antipoverty tool. However, participation in index insurance to this point has generally been in low. In this paper, we explore one factor that might potentially depress demand for index insurance: mistaken beliefs among farmers with respect to the distribution of the insured risk. Our experiences from an area-yield insurance pilot project for cotton farmers in the Pisco valley of Peru suggest that such errors are common. Lower demand means that not only are the benefits of index insurance not realized by households, but econometric measurement of the these benefits is more difficult due to low precision. One way to counteract these effects is a “randomized encouragement design,” i.e., the random assignment of positive economic incentives for the purchase of area-yield insurance, such as discount coupons. We examine the implications of a randomized encouragement design for econometric evaluation.
Performance Analysis of Decision Tree Algorithms on Mushroom Dataset

: Data mining is a process of extracting valuable information from vast dataset databases. This paper discusses data mining algorithms namely ID3, CART, and HoeffdingTree (HT) based on decision tree. Our goal is to assess the risk to human life through the consumption of mushrooms. Decision tree is used to classify the data with 22 attributes, to either edible or poisonous Mushrooms. Decision tree is used in this study as classification technique for analyzing mushroom data set. This experiment has been performed in R studio software environment. This study illustrates the accuracy of each classifier and the results are compared and discussed to which classifier is best for mushroom dataset. Hoeffding Tree provides better results with highest accuracy, low time and least error rate when compared with ID3 and CART.
As abelhas e seu serviço ecossistêmico de polinização

Com os avancos da agricultura, o desflorestamento, o desenvolvimento urbano e demais atividades antropicas, a biodiversidade esta ameacada. As populacoes de polinizadores naturais tambem diminuem, por nao encontrar mais recursos suficientes para alimentar-se e nidificar-se. Dessa forma, com esta revisao narrativa, buscou-se uma reflexao sobre a presteza das abelhas em seus servicos ecossistemicos. A polinizacao e um servico ecossistemico que tanto os sistemas naturais como agricolas dependem, mas que nao tem ganho a devida importância economica. As abelhas sao os principais agentes polinizadores, prestando um servico ecossistemico extremamente importante, pois alem de contribuirem com o meio ambiente auxiliando na disseminacao das plantas, garantindo a variacao genetica importante para o desenvolvimento das especies, sao produtoras de mel. A presenca de abelhas indica qualidade ambiental e, portanto a perda deste inseto ameaca inclusive a saude ambiental dos ecossistemas existentes.
BACKWARD COMPATIBILITY AS A KEY MEASURE FOR SMOOTH UPGRADES TO THE LHC CONTROL SYSTEM

It is a big challenge to smoothly upgrade the control system of a large operational accelerator such as the LHC without causing unnecessary downtime. We have identified backward compatibility as a key measure to achieve this, because a backward compatible component can be easily upgraded. This document describes the work the CERN Accelerator Controls group does to provide methods and tools supporting backward compatibility.
Internal and External Barriers to Energy Efficiency: Made-to-Measure Policy Interventions

This paper has two objectives. First it provides a correlation between internal and external barriers to energy efficiency and consumer behaviour related to two domains. It evaluates behaviour related to energy curtailment, which represents routine, repetitive effort to decrease consumption on a day-to-day basis. It also considers behaviour related to investments, which are one time actions such as purchasing new energy efficiency technologies. Second, it assesses the effectiveness of the different interventions and programs in addressing the two types of barriers (internal and external) with the aim of informing the policy debate. By assessing the value of a large number of interventions, this paper is one of the first that combines in a unified framework the main findings of different disciplines, from economics to psychology.
IMPLEMENTATION AND PERFORMANCE EVALUATION OF ENERGY STORAGE PACK SYSTEM BASED ON C-RATE

In this paper, energy storage system (ESS) pack of lithium battery is implemented and performance of system based on C-rate is evaluated. Structure, usability and functions of ESS pack system are described. In our scheme, 80 cell lithium battery is used. The result shows that by reducing c-rate more energy can be stored in ESS pack.
THE IMPACT OF U.S. NEWS & WORLD REPORT COLLEGE RANKINGS ON ADMISSIONS OUTCOMES AND PRICING POLICIES AT SELECTIVE PRIVATE INSTITUTIONS

Despite the widespread popularity of the U.S. News & World Report College rankings there has been no empirical analysis of the impact of these rankings on applications, admissions, and enrollment decisions, as well as on institutions' pricing policies. Our analyses indicate that a less favorable rank leads an institution to accept a greater percentage of its applicants, a smaller percentage of its admitted applicants matriculate, and the resulting entering class is of lower quality, as measured by its average SAT scores. While tuitionlevels are not responsive to less favorable rankings, institutions offer less visible price discounts in the form of slightly lower levels of expected self-help (loans and employment opportunities) and significantly more generous levels of grant aid. These decreases in net tuition are an attempt to attract additional students from their declining applicant pool.
Determining trends for perceived levels of corruption

The Transparency International Corruption Perceptions Index is a composite index with a focus on cross-section information. The usage of the data in the form of time series has been discouraged in the past, due to changes in the composition of sources. Basing assessments only on sources that continuously enter the index, such time series are provided here, ranging from 1995 to 2005. Panel data regressions reveal how the sources' time series information is related to each other, suggesting a method for assembling panel data. Regressing a linear time trend on the standardized sources provides an assessment of the significance of a simple trend for each of 61 countries.
The early versus the late accent-lending fall in Dutch : Phonetic variation or phonological difference?

There are two well-known models of Dutch intonation: the GDI or Grammar of Dutch Intonation and the autosegmental model formulated by Gussenhoven. Gussenhoven’s model distinguishes – at least – two different types of falling pitch accent (%H H*L and %H ! H*L), whereas the GDI recognizes only one type of accent-lending fall (‘A’). The aim of the experiments presented below is to find out whether Dutch has two types of falling pitch accent or not by investigating whether there is a systematic meaning difference associated with a difference in timing of the fall. Short sentences with an early fall, a late fall or a standard pointed hat contour (‘1&A’ or H*L) were presented in contexts varying the information status of the focused information, asking subjects to perform a number of comparison and rating tasks. Results indicate that the early and the late fall belong to separate linguistic categories.
Régularisation d ’ Images Multivaluées par EDP : Un Formalisme Commun pour Différentes Applications

Résumé Nous étudions la régularisation d’images multivaluées par des méthodes variationnelles et EDP. A partir de l’étude de l’existant, nous proposons un formalisme unificateur basé sur une interprétation très locale des processus de régularisation. Les équation générales obtenues sont alors spécialisées en une nouvelle EDP de lissage qui respecte mieux la géométrie locale des images vectorielles. Un schéma numérique spécifique est proposé et validé pour des problèmes classiques de traitement d’images : restauration, Inpainting, interpolation et visualisation de flots.
AN EVENT-DRIVEN NAVIGATION SYSTEM FOR CONTENTS REUTILIZATION

Our research group is creating navigation contents for Expo’70 Commemoration Park in Japan, and is developing navigation systems that will use these contents. Since it costs a lot of money and requires a lot of human resources to create useful and interesting navigation contents, it is difficult to create high-quality contents for a single small-scale system. Therefore, we propose a framework for constructing multiple navigation systems, without needing to make drastic modifications to the contents and systems, using our proposed event-driven platform. We constructed four navigation systems using the proposed framework with the navigation contents we created for Expo’70: a wearable navigation system, an AR navigation system, a kiosk-style navigation system, and a streaming navigation system. The two implemented systems received high praise from users in experimental demonstrations.
Improving Rice Grain Quality by Enhancing Accumulation of Iron and Zinc While Minimizing Cadmium and Lead

Iron (Fe) and zinc (Zn) are important trace elements for people’s health around the globe. A lot of people, especially children and woman, are suffering from malnutrition caused by Fe and/or Zn deficiency. The deficiency is more pronounced in some parts of Africa and Asia due to low income, which makes it difficult to afford meat or sea foods that are rich in Fe and Zn. Biofortification of Fe and Zn in rice is the most economical and conve - nient way to supplement these important minerals in the diet of poor people. However, besides Fe and Zn, rice also can accumulate heavy metals, such as cadmium (Cd) and lead (Pb), which are harmful to people, especially for kids’ health. Previous researches have shown that there are connections and discrepancies for metal absorption, translo - cation, and accumulation in rice. So it is imperative to review these issues. This chapter compares the physiological and molecular mechanisms of Fe, Zn, Cd, and Pb uptake, mobilization, and accumulation in rice and discusses the progress and strategies for not only increasing Fe/Zn but also decreasing Cd/Zn accumulation in rice. Cd/Pb in grains based on functional QTLs or genes. These cultivars show no agriculturally or economically adverse traits and can be applied sooner. On the other hand, modern transgenic technology provides perspectives for efficiently improving Fe/Zn content and decreasing Cd/ Pb content in rice grains to dietary significant levels for humans’ nutrition (As to Pb, more researches on QTL and genes still needed). Besides improving rice seeds, water and fertilizer management is also significantly related with increased Fe/Zn and decreased Cd/Pb in rice grains. More studies are still needed to optimize irrigation time, fertilizer categories, dosage, and application stages. In addition, although it is available to establish rice cultivars with high Fe or Zn content, or establish rice cultivars with low Cd or Pb separately, interactions among these metals need to be better understood, and more steps are still needed to cultivate rice with all these merits and without decreasing rice production.
Systems Pharmacology for the Study of Anticancer Drugs: Promises and Challenges

Johnson J Liu1*, Mingwei Chen2, Deming Gou3, Jun Lu4 and Shu-Feng Zhou5 1School of Medicine, Faculty of Health, University of Tasmania, Hobart, Tasmania 7001, Australia 2The First Affiliated Hospital of Xi’an Jiaotong University, Shaanxi 710061, China 3College of Life Sciences, Shenzhen University, Guangdong 518060, China 4School of Inter Professional Health Studies, and School of Applied Sciences, Faculty of Health and Environmental Sciences, and Institute of Biomedical Technology, Auckland University of Technology, Auckland 1142, New Zealand 5Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, Florida 33612, USA
Highly mismatched III–V semiconductor alloys applied in multiple quantum well photovoltaics

Adding dilute concentrations of nitrogen (N) or bismuth (Bi) into conventional III–V semiconductor alloys causes a large bowing of the bandgap energy due to the modification of the electronic band structure. This behaviour has attracted significant interest due to the resulting optical and electronic properties. Firstly, the authors present theoretical band structure models for GaAs-based dilute nitride, dilute bismide and dilute bismide-nitride alloys and then use them within current continuity equations to show the photovoltaic behaviour. To describe the band structures of these highly mismatched III–V semiconductor alloys, the authors introduce a 10-, 12- and 14-band k ⋅ p Hamiltonian for dilute nitride, dilute bismide and dilute bismide-nitride semiconductors, respectively. The authors then use this approach to analyse GaBiAs multi-quantum well p-i-n structures for photovoltaic performance. Through theoretical analysis the authors can: (i) elucidate important trends in the properties and photovoltaic performance of GaBiAs QW structures and (ii) comment generally on the suitability of GaBiAs alloys and heterostructures for applications in multi-junction solar cells. In particular, the authors identify and quantify the limitations associated with current GaBiAs solar cells, and describe the improvements in performance that can be expected pending further development of this emerging class of devices.
Seleção de Caracterı́sticas utilizando Busca Ordenada e um Classificador de Larga Margem Saulo

Resumo – Máquinas de Vetores Suportes têm sido amplamente utilizadas com bastante eficiência em problemas que possuem uma grande quantidade de variáveis ou caracterı́sticas. Neste sentido, torna-se importante o desenvolvimento de novas estratégias para a solução deste tipo de problema que se utilizem de critérios de seleção associados a este tipo de classificador. Neste trabalho propõe-se um novo método para a seleção de subconjuntos de variáveis que utiliza um processo de busca ordenada, também conhecido como best-first, para exploração do espaço de possı́veis candidatos. O algoritmo, denominado AOS, utiliza como medida de avaliação os valores de margem calculados a partir da utilização de um classificador de larga margem, denominado IMA. Este classificador, de grande eficiência computacional, permite grande flexibilidade e rapidez na obtenção dos valores de margem possibilitando a solução de problemas de tamanho razoável, com centenas de caracterı́sticas, sem que ocorra explosão combinatória. O algoritmo foi testado em vários problemas da literatura e seus resultados comparados à técnica mı́ope de subconjuntos aninhados denominada RFE-SVM. Uma importante contribuição teórica do trabalho se refere ao desenvolvimento do conceito de margem projetada. A utilização deste valor, computado como a projeção da margem real de um espaço em cada subespaço de dimensão inferior, associado ao algoritmo IMA, permitiu maior eficiência e rapidez na solução dos problemas de classificação e, portanto, no processo de busca como um todo.