Miracle-dz/UniFAR-FTUs huggingface dataset:
IDENTIFICATION OF SINGLE NUCLEOTIDE POLYMORPHISMS IN GROWTH HORMONE SECRETAGOGUE RECEPTOR (GHSR) GENE IN NATIVE EGYPTIAN CHICKENS

Growth hormone secretagogue receptor (GHSR) or Ghrelin receptor gene is legend for a peptide hormone produced by chicken proventriculus which stimulates growth hormone release and food intake. The purpose of this study was to determine single nucleotide polymorphisms (SNPs) in GHSR gene in six native Egyptian chicken breeds (Fayomi, Dandarawy, El-Salam, Dokki-4, Inshas, and Mandara) compared to Rhode Island Red (RIR). Blood samples were collected from these chickens at eight weeks of age. A PCR product of 598 bp, GHSR was amplified using polymerase chain reaction (PCR) and subsequently, subjected to sequence analysis to identify its different allelic patterns. Two different SSCP banding patterns (TT and TC) were detected. Nucleotide sequencing revealed presence of a novel T40C SNP in the first intron of GHSR at nucleotide number 59 before the second exon. Results from SSCP and sequencing denoted absence of CC genotype in all examined chicken breed. Although, we did not perform association analysis for these genotypes due to small population size, the present results put the basis for further studies to associate this SNP and others in GHSR with growth traits in local chicken breeds.
Who are better leaders; Transformational vs Transactional Leaders? Women vs Men?

There are numerous leadership theories and which leadership style is the most effective is often debated. Gender has been implicated as playing a significant role, as stereotypical feminine characteristics are similar to transactional leadership characteristics. Previous studies have also implicated transformational leadership as the most effective style, thus suggesting that women would be better leaders. However, there are an increasing number of studies that would suggest that gender plays a minimal role. Likewise, the organizational context would appear to be a significant driver of which type of leader emerges; rather than a single leadership style of transformational or transactional, a combination of both is likely the most effective.
Near- and far-field dispersal modelling of organic waste from Atlantic salmon aquaculture in fjord systems

Near- and far-ﬁeld dispersal modelling of organic waste from Atlantic salmon aquaculture in fjord systems. 73: The ability to achieve environmentally sustainable Atlantic salmon aquaculture in coastal fjord ecosystems is currently constrained by our limited knowledge of the regional interactions and fate of organic efﬂuents on benthic ecosystems. A ﬁrst step in addressing this limitation is to establish predictive modelling tools to better understand local and regional dispersion of organic efﬂuents in the wider ecosystem. By combining settling velocity of faecal waste from different sizes of Atlantic salmon, a three-dimensional hydrodynamic model coupled with a particle tracking model and farm management data, this study presents a ﬁrst-generation generic near- and far-ﬁeld efﬂuent dispersion model to predict the spread of particulate organic waste into fjord ecosystems. Simulations predict that . 75% of organic efﬂuents are dispersed to near-ﬁeld sites ( , 500 m from the release point), while a small proportion of particulate organic efﬂuents (up to 2.7%) are dispersed to far-ﬁeld sites ( . 2 km). Thesesimulationsindicatethatorganicefﬂuentsfromﬁshfarmsmaybedispersedoverlargeareasoffjordsystems. Theinputofmeasured “mass fractions” settling velocities of faecal waste from different sizes of Atlantic salmon ensured that modelled predictions of near and far-ﬁeld dispersion of organic material over a production cycle were in the range of observed POM ﬂuxes.
A STUDY OF PICTORIALMETAPHOR IN ADVERTISEMENTS

Pictorial metaphors are one of the non-verbal metaphors that commonly appear in advertisements. These metaphors include source and target domains. When both of these domains are visually represented, they are called monomodal. Whereas when verbal representation is used with visual one, they are called multimodal. Pictorial metaphors can be contextual when only one domain is visually represented and the other is contextually known. Pictorial metaphor can also besimile when both domains express the point of similarity between them, or hybrid when the source and target domains are mixed. This paper aims to identify the use of pictorial metaphor in American and British advertisements and show how they are similar or different. To achieve the aims of the study, an eclectic model of Forceville's (1996 ) and Evans and Green ́s (2006) is used to analyze 10 selected American and British advertisement.The analysis of data revealsthat there are some similarities and differences in American and British pictorial metaphor advertisements. It also concludes that hybrid pictorial metaphor is the most repeatedly used in pictorial metaphor in both American and British advertisements.
Radiomic features of primary tumor by lung cancer stage: analysis in BRAF mutated non-small cell lung cancer

Background The clinical features and traditional semantic imaging characteristics of BRAF-mutated non-small cell lung cancer (NSCLC) have been previously reported. The radiomic features of BRAF-mutated NSCLC and their role in predicting cancer stage, however, have yet to be investigated. This study’s goal is to assess the differences in CT radiomic features of primary NSCLC driven by BRAF mutation and stratified by tumor-node-metastasis (TNM) staging. Methods Our IRB approved study included 62 patients with BRAF mutations (V600 in 27 and non-V600 in 35 patients), who underwent contrast-enhanced chest CT. Tumor stage was determined based on the 8th edition of TNM staging. Two thoracic radiologists assessed the primary tumor imaging features such, including tumor size (maximum and minimum dimensions) and density (Hounsfield units, HU). De-identified transverse CT images (DICOM) were processed with 3D slicer (Version 4.7) for manual lesion segmentation and estimation of radiomic features. Descriptive statistics, multivariate logistic regression, and receiver operating characteristics (ROC) were performed. Results There were significant differences in the radiomic features based on cancer stages I-IV with the most significant differences between stage IV and stage I lesions [AUC 0.94 (95% CI: 0.86–0.99), P<0.04]. There were also significant differences in radiomic features between stage IV and combined stages I-III [40/113 radiomic features; AUC 0.71 (95% CI: 0.59–0.85); P<0.04–0.0001]. None of the clinical (0/6) or imaging (0/3) features were significantly different between stage IV and combined stages I–III. Conclusions The radiomic features of primary tumor in BRAF driven NSCLC significantly vary with cancer stage, independent of standard imaging and clinical features.
Rio 2016 Olympics: analysis of the tourist perception of quality using TOURQUAL

The Rio 2016 Olympic Games was a mega event that changed the Brazilian tourism structure, particularly in the city of Rio de Janeiro. This article focuses on the evaluation of the quality of services offered to tourists, and the study analyzes tourists perceptions of quality. This is a quantitative, exploratory, descriptive research using a survey and based on the Tourqual indicators. Interviews of 1912 tourists were carried out throughout the event. Data were treated and analyzed by means of descriptive statistics, student's t-test for mean comparison and Spearman correlation to define which indicators most influenced the mega event’s overall score. The main results indicate that the event had an evaluation index of 9.28 and the indicators of comfort, beauty, acoustics and temperature of the Olympic venues, variety of activities and transportation, were the indicators that most influenced the positive perception of quality at the event. Normal 0 21 false false false PT-BR X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:. 0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Liberation Serif","serif";}
THE CRISIS REALLY HURT ? Introduction to the problem

There are good reasons to expect that the 1980/1982 economic recession has `hurt' the average citizen in afflicted countries, in particular that it has impaired mental and physical health and has lowered satisfaction. Yet, there are also good reasons to doubt these claims. It is worth knowing whether the recession has in fact done damage or not, and if so -, whom it has hurt most. It is fairly well possible to find that out.
Studies on physical, chemical and mineral evaluation of oats (Avena sativa)

The present investigation was carried out to study the physical, chemical and mineral composition of rolled oats. The analysis of the physical properties of oats showed that the average 1000 Kernel weight was 30.89 gms. Bulk density of oats was found to be 0.419 gm/cm³ whereas true density was 1.19 gm/cm³. Porosity of rolled oats was recorded to be 64.45 per cent, whereas Angle of repose was 46. 4ᵒ for oats. The results of the chemical analysis showed that the content of moisture in the oats was 4.206%, ash content was about 1.97 per cent, total carbohydrates ranged about 55.75 per cent, the crude protein content was 12.62 per cent, crude fat content was 6.91 per cent and the total fiber content was around 13.65 per cent. The concentration of calcium was recorded to be 60.13mg/100g, oat was observed to have 474.06mg/100g of phosphorus, whereas 115mg/100g of magnesium and 9.23mg/100g of iron was found in oats. The potassium content was observed to be 337mg/100g.
Comparative proteome analysis reveals VPS28 regulates milk fat synthesis through ubiquitylation in bovine mammary epithelial cells

In our previous study, we found that VPS28 (vacuolar protein sorting 28 homolog) could alter ubiquitylation level to regulate milk fat synthesis in bovine primary mammary epithelial cells (BMECs). While the information on the regulation of VPS28 on proteome of milk fat synthesis is less known, we explored its effect on milk fat synthesis using isobaric tags for relative and absolute quantitation assay after knocking down VPS28 in BMECs. A total of 2,773 proteins in three biological replicates with a false discovery rate of less than 1.2% were identified and quantified. Among them, a subset of 203 proteins were screened as significantly down-(111) and up-(92) regulated in VPS28 knockdown BMECs compared with the control groups. According to Gene Ontology analysis, the differentially expressed proteins were enriched in the “proteasome,” “ubiquitylation,” “metabolism of fatty acids,” “phosphorylation,” and “ribosome. ” Meanwhile, some changes occurred in the morphology of BMECs and an accumulation of TG (triglyceride) and dysfunction of proteasome were identified, and a series of genes associated with milk fat synthesis, ubiquitylation and proteasome pathways were analyzed by quantitative real-time PCR. The results of this study suggested VPS28 regulated milk fat synthesis was mediated by ubiquitylation; it could be an important new area of study for milk fat synthesis and other milk fat content traits in bovine.
Amelioration of salinity stress in transplant Aman rice through application of gypsum

The experiment was carried out at the farmyard of the Bangladesh Institute of Nuclear Agriculture (BINA), Mymensingh, during the period from August 2017 to January 2018 to investigate the ameliorative effect of gypsum application on plant characteristics and yield, under various levels of salinity stress, of transplant Aman rice cv. Binadhan-10. The experiment was designed with three salinity levels such as control (M0), 5 dSm-1 (M1) and 10 dSm-1 (M2) NaCl, two gypsum levels such as control (G0) and 150 kg ha-1 (G1). To ameliorate the salinity stress t, gypsum was applied. Results revealed that the different levels of salinity had a significant adverse effect on plant height, the total number of tillers hill-1, number of effective tillers hill-1, panicle length, number of sterile spikelets panicle-1, 1000-grain weight, number of grains panicle-1, grain yield, straw yield, biological yield and harvest index. All the plants were affected badly when they were exposed to 10 dSm-1 salinity level. At salinity level of 5 dSm-1 grain yield reduction was 37%, which could be minimized to 14% by the application of gypsum. In case of straw yield, A similar amelioration effect was also observed. At 5 dSm-1 the grain yield was more improved from 3.46 t ha-1 to 3.93 t ha-1 when gypsum was applied. The grain yield reduction could further be improved at salinity level of 10 dSm-1 from 65% to 36% with the application of gypsum. At 10 dSm-1 the grain yield was more improved from 1.95 t ha-1 to 2.55 t ha-1 when gypsum was applied. The results of the study conclude that salinity stress could be ameliorated through the application of gypsum @ 150 kg ha-1 in transplant Aman rice cv. Binadhan-10.
Inflation-Unemployment Trade-Offs In ASEAN-10

This study empirically explores the nature of inflation-unemployment dynamic causal relationships both in the short and long-run in the ASEAN-10 over the 1989-2018 period. Based on the panel cointegration test, the study documented a long-run equilibrium between inflation and unemployment. Using the Vector Error Correction Model (VECM) analysis, the study found an insignificant inflation-unemployment relationship in the short-run. However, in the long-run, inflation is found to affect the unemployment rate positively. Our results from the Variance Decompositions (VDCs) analysis also supported these findings, where the unemployment responded at the more significant percentage to shocks in inflation compared to the response of inflation to shocks in unemployment. These findings only supported the relevance of the Phillips curve theory in the long-run. Overall, these findings imply that although inflation targeting policy is not relevant to the short-run, it becomes crucial and effective to reduce the unemployment rate in ASEAN-10 in the long-run. JEL Classifications : E52, E58, J64 How to Cite: Lisani, N. , Masbar, R. , & Silvia, V. (2020). Inflation-Unemployment Trade-Offs In Asean-10. Signifikan: Jurnal Ilmu Ekonomi, 9 (2), 241-256. https://doi.org/10.15408/sjie.v9i2. 16346.
Virtual screening of triazoles inhibitors of 11β-hydroxysteroid dehydrogenaseenzymes using -ADME-moleculardocking, and molecular dynamics simulation studies

Hypertension, or elevated arterial blood pressure, is a substantial public health problem. The two 11β hydroxysteroid dehydrogenase (11β HSD) isozymes catalyze the interconversion of cortisol and cortisone. Our research consists in studying the inhibition of the enzymes with some derivatives of 1,2,4 triazoles by means of molecular docking and dynamics approaches. The interactions between the studied inhibitors and our target were further explored through molecular docking and molecular dynamics simulations, in the presence of water molecules. The molecular dynamics study was done for the best der ivatives of 1,2,4 triazoles inhibitors (deducted from the docking best scores for L2 and L1, and lowest score for Lref) A f e w k e y r e s i du e s N 14 with oxygen receptor interaction H donor) at the binding site of (11β HSD1) and (11β HSD2) were identified. Obtained Docking and molecular dynamics result, both leads to the same conclusion and predict that L2 subsisted derivatives of 1, 2, 4 triazoles is the best inhibitor candidate.
The role of gasotransmitters in movement of stomata: mechanisms of action and importance for plant immunity

Stomatal guard cells are specialized epidermal cells regulating gas exchange. The ability to open or close in response to external and internal cues makes stomata a dynamic and fascinating system. Stomatal closure upon infection ensures restriction of pathogen entry into the plant and forms an essential component of innate immunity. The opening or closure of stomata is dependent on the turgidity or flaccidity of guard cells, respectively, facilitated by several signaling components, including reactive oxygen species, nitric oxide (NO) and Ca2+. Among these, NO is the most extensively studied gasotransmitter. Its pivotal role in stomatal closure by modulating various downstream components as well as regulation of crucial proteins by post-translational modifications makes NO an essential factor. Two more gasotransmitters, carbon monoxide and hydrogen sulfide, also trigger stomatal closure. Other gaseous molecules, like ethylene, methane, sulfur dioxide, ozone, and CO2, can modulate stomatal closure, but they are not considered strictly as gasotransmitters due to specific criteria. We review the signaling events in guard cells triggered by these gasotransmitters leading to stomatal closure. We point out the dual role of NO to promote stomatal closure and stomatal opening. Both NO and H2S help in reinforcing the innate immunity against pathogen attack. Although there is extensive information on the mechanism of NO action on stomata, the enzymatic source of NO or CO is still ambiguous. Similarly, research is warranted to establish the relative importance of and interactions among the three main gasotransmitters. Further studies on gasotransmitters would answer the ambiguity about their functions and confirm if they can act independently.
Design and Analysis of a Modified TG Rectifier with Substrate Voltage Compensation Techniques at 45 nm Technology for High Frequency Low Power RF Energy Harvesting

- The development of latest generation of wireless communication standards in the recent years has created enormous possibility to deploy high speed wireless network throughout the globe. There is always demand for high speed, seamless data connectivity. But it is a well-known fact that the increase in speed always makes the power consumption higher. Also while attempting to cater to the need of connectivity to a remote location, the major bottleneck is the availability of power. Hence incorporating self-sustainability to a wireless network is becoming the need of the hour. Radio frequency (RF) energy harvesting (EH) is gaining much attention in contemporary communications in this context. In the design of an EH system, the high frequency rectifier plays a significant role. Apart from several design hurdles that exist in a high frequency rectifier, to attain a high percentage conversion efficiency (PCE) at lower input power is the primary design challenge. This paper presents a design of a modified transmission gate (TG) based high frequency rectifier with two substrate voltage compensation techniques, viz. capacitor and MOS based compensation for RF EH system.The proposed capacitor and MOS based techniques enable the rectifier to achieve a PCE upto 86% and 92% at -5dBm respectively in its single stage implementation. This can be claimed to be the highest in-class efficiency as compared to recently published works. The frequency responses with both the techniques depict a wide band performance covering all popular wireless bands. The dynamic power dissipations (DPD) observed are 12nW and 16nW at -5dB, whereas the leakage power (LP) is 20x10-51W and zero respectively. Further such an performance are obtained using minimal number of transistors, viz. 4 and 5 respectively.
ANALYSIS OF IMPLEMENTING NETWORK INTRUSION DETECTION (NIDS) ALGORITHMS USING MACHINE LEARNING

Although advanced Machine Learning (ML) techniques have been adopted for detecting intruders, the attack remains a major Internet threat. The main objective of this project is to identify or detect attacks that have occurred on the network. Now the growth of social media will increase day by day. However, it is difficult to detect attacks. This project will dynamically identify the attack by analyzing information from the KDDCUP dataset.The naive bay classification algorithm is used to classify the data presented on the network.
EFFICACY OF PRAZIQUANTEL LOADED CHITOSAN NANOPARTICLES AGAINST BOTH ADULT AND SCHISTOSOMULA STAGES OF SCHISTOSOMA MANSONI

Schistosomiasis is the 2nd most common parasitic disease that causes around 300000 deaths annually worldwide. The main antischistosomal therapy; praziquantel (PZQ) has many imperfections e.g. resistance, frail impact against premature stages and many side effects. This raised the need to find a substitute or to repair PZQ defects. This work aimed to assess value of loading PZQ to chitosan nanoparticles (CS-NPs) regarding usage of lower PZQ dose (to decrease side effects) and broadening its spectrum (to involve premature stages of Schistosoma mansoni). This study involved 11 mice groups. The first four groups served for schistosomula studies (mice were euthanized 17 days post infection (d.p.i.). Group I served as positive schistosomula controls. Groups II, III and IV received pre-maturation treatments 10 d.p.i. The last seven groups served for adult worm studies (mice were euthanized 50 d.p.i.). Group V served as positive adult controls. Groups VI, VII and VIII received pre-maturation treatments 10 d.p.i. Groups IX, X and XI received post-maturation treatments 45 d.p.i.Drug efficacy against schistosomula was assessed by counting and scanning electron microscopy (SEM) of the retrieved schistosomula. Efficacy against adult worms was assessed by studying worm load, ova count, oogram, granuloma studies and SEM of adult worms. Results showed that, PZQ loaded CS-NPs (PZQ/CS-NPs) significantly reduced schistosomula count with no morphological changes. Regarding adults, PZQ/CS-NPs achieved a statistically significant higher reduction of all assessed parameters - compared to traditional PZQ - especially when administered as a post-maturation treatment. Regardless of absent morphological changes of schistosomula, clear morphological deformities appeared when these schistosomula were permitted to develop into adults.
Formative e-Assessment for Moroccan Polyvalent Nurses Training: Effects and Challenges

Formative e-assessment is an innovative teaching practice to enhance learning. However, teachers encounter multiple difficulties in integrating it. In this article,we present the results of an exploratory study conducted with nurses teachers (n=10) to identify the challenges that prevent the integration of technology in formative assessment. Moreover,we expose the results of a learning experience in order to measure the effect of formative e-assessment on teaching the course of surgical nursing care. Our population includes fifty-eight (n= 58) polyvalent student nurses, divided into two groups: an experimental group and a control group. Only the experimental group has been invited to respond to self-assessment quizzes posted online after the course sessions. The positive effect on learning was demonstrated, after comparing the summative scores of the two groups (the p-value of the Mann-Whitney Test is less than 0.05). Also, the qualitative study has demonstrated challenges in ICT integration, absence of institutional directives recommending the use of ICT, required technical skills, diversity of tasks required of teachers, lack of material resources and absence of an institutional platform. The obtained results conclude that the formative evaluation facilitated by ICT positively influences the students’ summative scores. This conclusion should encourage and motivate teachers to integrate ICT into their formative evaluation practices in order to better achieve the learning objectives. However, it seems necessary to involve the actors responsible for training nurses in order to support teachers in the pedagogical integration of ICT.