Miracle-dz/UniFAR-FTUs huggingface dataset:
Fine motion planning in self overlapping driving channels and multiple mobile vehicle coordination

After a short overview of a monitoring and navigation system for mobile vehicles (called MONAMOVE) consisting of multiple carriers of different size and an environment monitoring system, the navigation principle using one global navigator for gross motion planning and several local ones for fine motion planning is described. The coordination of multiple vehicles with their individual trajectories computed by the local navigators is managed by the global navigator using automatically computed crossings lying on a regular grid. This fine motion planning approach fulfills constraints like right orientation and continuous curvature along the paths; it bases on the computation of right oriented points which lie inside a driving channel (DC). These points are connected to the best right oriented line sequence without being a stupid following of the right border of the DC. Various extensions of this work are proposed.
Coexisting causes of ischemic stroke.

BACKGROUND Coexistence of multiple potential causes of cerebral infarct (MPCI) has been poorly studied. OBJECTIVE To determine the risk factors, clinical findings, and topographical patterns of patients with at least 2 potential causes of cerebral infarct. DESIGN Data analysis from a prospective acute stroke registry (the Lausanne Stroke Registry, Lausanne, Switzerland) in a community-based primary care center. RESULTS Among 3525 patients with first-ever ischemic stroke consecutively admitted to a primary care stroke center, 250 patients (7%) had at least 2 MPCIs, with the following subgroups: large artery disease and a cardiac source of embolism (LAD + CSE) (43%), small artery disease and CSE (SAD + CSE) (34%), LAD + SAD (18%), and LAD + SAD + CSE (5%). Hypertension, cardiac ischemia, and a history of atrial fibrillation predominated in the LAD + SAD + CSE subgroup (P<.001), while cigarette smoking was more prevalent in the LAD + SAD subgroup (P<.05). A decreased level of consciousness and speech disorders were more common in the LAD + CSE subgroup (P<.001). Lacunar syndromes predominated in the LAD + SAD subgroup. Pure motor stroke was the most frequent lacunar syndrome in all subgroups, but sensory motor stroke predominated in the LAD + CSE subgroup (P<.05). The outcome at 1 month was worse in the LAD + CSE and SAD + CSE subgroups (P<.001). Other stroke characteristics and clinical features did not differ significantly between the 4 subgroups of patients with MPCI. CONCLUSIONS Our findings suggest that MPCIs are uncommon. The most frequent association is LAD + CSE. Topographical patterns of stroke and clinical characteristics in patients with MPCI only rarely allow emphasis of a preeminent cause. Arch Neurol. 2000;57:1139-1144
Temporalité et récit dans l’acquisition du langage en situation bilingue

Les contributions ici rassemblees portent sur l’appropriation par l’enfant bilingue des moyens d’exprimer la temporalite dans ses langues — et ce de facon privilegiee a travers l’activite de construction de recits. L’accent est mis sur l’acquisition du langage et des langues, plus que sur l’acquisition du bilinguisme ; et les contributions sont centrees sur un domaine notionnel central dans le langage, et particulierement fecond, car il concerne tous les aspects de sa structuration : le domaine de la temporalite.On tente d’apporter, a partir de situations linguistiques variees, et sous l’angle specifique de l’expression du temps et des conduites narratives, des elements de reponse aux grandes questions suivantes :• L’acquisition de plusieurs langues premieres suit-elle pour chacune les etapes de developpement decrites chez l’enfant unilingue ? • Comment se manifestent la dominance d’une langue sur l’autre et le changement de dominance ? • Dans quelle mesure, lorsqu’il existe une asymetrie d’exposition de l’enfant aux deux langues, a-t-on acquisition simultanee de deux langues premieres, ou acquisition successive d’une langue premiere et d’une langue seconde ? • Dans quelle mesure les phenomenes de dominance montrent-ils que la structure de l’acquisition est regie par le developpement cognitif general ou par la structuration specifique du domaine linguistique ?
The Serpin Inhibitory Mechanism Is Critically Dependent on the Length of the Reactive Center Loop*

The recent crystallographic structure of a serpin-protease complex revealed that protease inactivation results from a disruption of the catalytic site architecture caused by the displacement of the catalytic serine. We hypothesize that inhibition depends on the length of the N-terminal portion of the reactive center loop, to which the active serine is covalently attached. To test this, α1-antitrypsin Pittsburgh variants were prepared with lengthened and shortened reactive center loops. The rates of inhibition of factor Xa and of complex dissociation were measured. The addition of one residue reduced the stability of the complex more than 200,000-fold, and the addition of two residues reduced it by more than 1,000,000-fold, whereas the deletion of one or two residues lowered the efficiency of inhibition and increased the stability of the complex (2-fold). The deletion of more than two residues completely converted the serpin into a substrate. Similar results were obtained for the α1-antitrypsin variants with thrombin and for PAI-1 and PAI-2 with their common target tissue plasminogen activator. We conclude that the length of the serpin reactive center loop is critical for its mechanism of inhibition and is precisely regulated to balance the efficiency of inhibition and stability of the final complex.
PPAndroid-Benchmarker: Benchmarking Privacy Protection Systems on Android Devices

Mobile devices are ubiquitous in today's digital world. While people enjoy the convenience brought by mobile devices, it has been proven that many mobile apps leak personal information without user consent or even awareness. That can occur due to many reasons, such as careless programming errors, intention of developers to collect private information, infection of innocent apps by malware, etc. Thus, the research community has proposed many methods and systems to detect privacy leakage and prevent such detected leakage on mobile devices. This is a to do note at margin While it is obviously essential to evaluate the accuracy and effectiveness of privacy protection systems, we are not aware of any automated system that can benchmark performance of privacy protection systems on Android devices. In this paper, we report PPAndroid-Benchmarker, the first system of this kind, which can fairly benchmark any privacy protection systems dynamically (i.e., in run time) or statically. PPAndroid-Benchmarker has been released as an open-source tool and we believe that it will help the research community, developers and even end users to analyze, improve, and choose privacy protection systems on Android devices. We applied PPAndroid-Benchmarker in dynamic mode to 165 Android apps with some privacy protection features, selected from variant app markets and the research community, and showed effectiveness of the tool. We also illustrate two components of PPAndroid-Benchmarker on the design level, which are Automatic Test Apps Generator for benchmarking static analysis based tools and Reconfigurability Engine that allows any instance of PPAndroid-Benchmarker to be reconfigured including but not limited to adding and removing information sources and sinks. Furthermore, we give some insights about current status of mobile privacy protection and prevention in app markets based upon our analysis.
New approaches for synthesis of redundant combinatorial logic for selective fault tolerance

With shrinking process technologies, the likelihood of mid-life faults in combinatorial logic is increasing. Approximate logic functions are a promising approach to mitigate such faults as the technique can be applied to any digital circuit, it protects against multiple fault models and offers a trade-off between increased area and fault coverage. In this paper we present a new algorithm for generating approximate logic functions. The algorithm considers the failure probabilities of the gates and it uses a sum of product (SOP) representation. The results on some circuits show that FIT rate can be reduced by 75% with an area penalty of 46% and inserting only two additional layers of logic.
Rotating Gaussian wave packets in weak external potentials

We address the time evolution of two- and three-dimensional nonrelativistic Gaussian wave packets in the presence of a weak external potential of arbitrary functional form. The focus of our study is the phenomenon of rotation of a Gaussian wave packet around its center of mass, as quantified by mean angular momentum computed relative to the wave packet center. Using a semiclassical approximation of the eikonal type, we derive an explicit formula for a time-dependent change of mean angular momentum of a wave packet induced by its interaction with a weak external potential. As an example, we apply our analytical approach to the scenario of a two-dimensional quantum particle crossing a tilted ridge potential barrier. In particular, we demonstrate that the initial orientation of the particle wave packet determines the sense of its rotation, and report a good agreement between analytical and numerical results.
Comparative experiment of color and structure on microwave and microwave-vacuum puffing of blackcurrant's chip

A comparative study on the microwave, and microwave- vacuum of blackcurrant's chip has been done. In microwave-vacuum puffing, the microwave intensity and vacuum pressure were set at 20W/g and 30 kPa, respectively; Except for vacuum pressure, the conditions of microwave puffing were the same with microwave-vacuum. Comparing to the color and structure characteristics of blackcurrant's chip, it was known that comparing to microwave puffing, fracturing distance and fracturing energy of blackcurrant's chip decreased by 0.37mm and 754.33g·s respectively, fracturing slope increased by 1449.25g/s, hardness decreased by 1378.81g. Value of lightness, redness and chroma increased by 4.48, 4.9, 3.18 respectively, while yellowness and hue decreased by 5.66 and 11.09 using microwave vacuum puffing. So microwave vacuum technique is a potential method to puff blackcurrant's snack with high quality.
Effect of Radiotheraphy on Impaired Aortic Elasticity and Stiffness in Patients With Breast Cancer

We evaluated the effect of radiotherapy (RT) on the elastic properties of the aorta using echocardiography in patients with breast cancer (BC). A total of 105 women with left-sided epidermal growth factor receptor 2 (erb-2) BC were divided into 2 groups, group 1 with patients who did not receive RT and group 2 with patients who received RT. In all patients, echocardiographic examination and serum high-sensitivity C-reactive protein (hs-CRP) levels were determined. A significant decrease in aortic distensibility (AD) and increase in hs-CRP were seen from group 1 to group 2. The AD was inversely correlated with left ventricle diastolic diameter, systolic blood pressure (SBP), left atrial diameter, age, and RT dose. The AD was significantly related to age, SBP, and RT dose. Increased RT dose is significantly correlated with impaired elastic properties that may contribute to the relation of RT and increased rate of cardiovascular events among patients with BC who received RT.
A Role for Lipid Shells in Targeting Proteins to Caveolae, Rafts, and Other Lipid Domains

The surface membrane of cells is studded with morphologically distinct regions, or domains, like microvilli, cell-cell junctions, and coated pits. Each of these domains is specialized for a particular function, such as nutrient absorption, cell-cell communication, and endocytosis. Lipid domains, which include caveolae and rafts, are one of the least understood membrane domains. These domains are high in cholesterol and sphingolipids, have a light buoyant density, and function in both endocytosis and cell signaling. A major mystery, however, is how resident molecules are targeted to lipid domains. Here, we propose that the molecular address for proteins targeted to lipid domains is a lipid shell.
No vasoactive role of the angiotensin II type 2 receptor in normotensive Wistar rats.

OBJECTIVE To investigate the vasoactive consequences of angiotensin II type 2 receptor stimulation in vivo. DESIGN AND METHODS Three consecutive 10 min intravenous infusions of angiotensin (Ang) II (100, 300 and 1000 ng/kg per min) were given to 20 pentobarbitone-anaesthetized normotensive Wistar rats (weight 330+/-6 g, mean +/- SEM). The rats had been pretreated with saline (n = 8), the angiotensin II type 1 receptor antagonist, irbesartan (100 microg/kg per min for 30 min, n = 6), or the angiotensin II type 2 receptor antagonist, PD123319 (20 microg/kg per min for 30 min followed by continuous infusion throughout the entire experiment, n = 6). Regional haemodynamic effects of Ang II were studied using the radioactive microsphere method. RESULTS Ang II increased mean arterial blood pressure (MAP) and heart rate by, maximally, 44+/-9 and 26+/-6%, respectively (P < 0.05 compared with baseline), and decreased cardiac output and systemic vascular conductance (cardiac output/MAP) by, maximally, 24+/-8 and 47+/-4%, respectively (P < 0.05 compared with baseline). The Ang II-induced decrease in systemic vascular conductance was caused by decreases in vascular conductances (regional flow/MAP) of the gastrointestinal tract (52+/-4%), kidney (63+/-3%), skeletal muscle (39+/-8%), skin (63+/-4%), mesentery + pancreas (32+/-11%), adrenal (27+/-11%) and spleen (57+/-6%) (all P < 0.05 compared with baseline). Irbesartan increased baseline vascular conductances in adrenal, brain and kidney, and inhibited all haemodynamic responses induced by Ang II. PD123319 affected neither baseline values nor the Ang II-induced haemodynamic responses. CONCLUSIONS Ang II-induced systemic and regional haemodynamic effects in normotensive Wistar rats are mediated exclusively via angiotensin II type 1 receptors. No evidence for angiotensin II type 2 receptor-mediated vasoactive responses was obtained.
Cerebral hydrodynamics imaging : from physiology to pathology

Le developpement de sequences specifiques sensibles au flux (PC) en imagerie par resonance magnetique (IRM) a permis de realiser une etude non invasive des interactions hydrodynamiques entre les flux vasculaires et de liquide cerebro-spinal (LCS) intracrâniens. Grâce a un logiciel semi-automatique de traitement des images, nous avons analyse ces interactions dans differentes populations. L’etude du systeme veineux chez 18 jeunes sujets sains a montre l’heterogeneite des debits, la lateralisation du drainage et le role du reseau accessoire extrajugulaire, ainsi que les pulsatilites differentes entre sinus et veines jugulaires. Des exemples de thromboses veineuses ont montre le role des veines dans la regulation de la pression intracrânienne. Cette technique a ete utilisee pour apprehender la physiopathologie des pathologies neurodegeneratives. Les effets du vieillissement physiologique sur les debits arteriels, et sur la dynamique de circulation du LCS ont d’abord ete etudies. L’apport de la PC-IRM dans le diagnostic des hydrocephalies obstructives par stenose de l’aqueduc a ete evalue chez 17 patients hydrocephales, avec les consequences sur le choix therapeutique et le suivi. Dans le cadre des demences, la PC-IRM a permis de decrire les modifications de flux observees dans l’Hydrocephalie a Pression Normale, la Maladie d’Alzheimer, et les etats pre-dementiels (MCI), et de proposer des theories physiopathologiques ainsi que des aides au diagnostic differentiel entre ces etats. Enfin, d’autres applications cliniques possibles (syringomyelie, post-radiotherapie ou post-chirurgie) sont presentees afin d’illustrer l’interet clinique et scientifique de ces evaluations.
Relación de los hábitos de práctica deportiva con el pensamiento hacia la Educación Física

RESUMEN El pensamiento del alumno de Educacion Secundaria Obligatoria hacia la Educacion Fisica es un tema de gran interes entre los docentes. Existen numerosas variables que determinan dicho pensamiento. En el presente trabajo hemos analizado la relacion entre la practica deportiva extraescolar con otros aspectos de la Educacion Fisica, tales como, los contenidos y objetivos, la importancia y el interes que el alumno concede a la Educacion Fisica, la valoracion y la utilidad de las clases, la actitud del profesor y el entorno socio-afectivo de practica. Para ello hemos utilizado el Cuestionario para el Analisis del Pensamiento del Alumno en Educacion Fisica (C.A.P.A.E.F.) elaborado para esta investigacion, aplicandolo a una muestra de 1499 estudiantes de primer y segundo ciclo de Ensenanza Secundaria Obligatoria de la Region de Murcia. Para el analisis de resultados hemos realizado estadisticos descriptivos de todas las variables, asi como analisis de independencia entre variables mediante las pruebas de Chi-cuadrado de Pearson completada con analisis de residuos tipificados corregidos. Las principales conclusiones a las que hemos llegado nos muestran que segun se incrementa la practica deportiva extraescolar las clases de Educacion Fisica resultan mas faciles, motivantes y utiles. Se valora positivamente que el profesor anime a practicar en horario extraescolar y las sesiones semanales resultan insuficientes. De la misma manera, a mayor cantidad de practica, el contenido mejor valorado es la Condicion Fisica y la Salud, orientando la misma hacia la competicion. La practica fisico-deportiva de los padres, hermanos y amigos tiene una relacion directa con la practica del alumno.
Electrochemistry, the past thirty and the next thirty years : a volume in honor of J. O'M. Bockris

Some time ago a group of present and former collaborators of Professor John O'M. Bock ris, following a suggestion by Professor J. D. Mackenzie (Los Angeles), conceived the idea of an International Symposium devoted to reviewing the active and developing aspects of the science of electrochemistry. From this beginning has sprung the "Electrochemistry Symposium-The Past Thirty and the Next Thirty Years," which took place at Imperial College, London, from April 3-6, 1975. The plan for this symposium is unusual, since it features pairs of invited addresses, one to summarize the "state of the art" and the other to suggest directions for future re search in particular aspects of electrochemistry. This volume of proceedings gives these papers in their fmal, considered, and fully referenced form, arranged in the sequence of their delivery at the symposium. Also in cluded are introductory addresses given by Professor Ubbelohde, Professor Frumkin, Dr. Egan, and Dr. Inman. Both aspects of nearly every topic, plus the discussions, are integrated in a Report or Summary. A synopsis of the matters raised at the symposium and prepared by Professor John O'M. Bockris closes this volume. The cooperation of Plenum Press, New York, is gratefully acknowledged. "
Quercetin and naringenin transport across human intestinal Caco-2 cells.

OBJECTIVES Flavonoids are phenolic compounds found in most edible fruits and vegetables. Previous studies have demonstrated their biological and beneficial effects on human health. However, their bioavailability and, in particular, their intestinal absorption mechanism have not yet been clearly identified. The aim of our work was to quantify and to characterize in vitro the nature of the transport of two flavonoids distinguished by their physicochemical and pharmacological properties: quercetin, a flavan-3-ol, and naringenin, a flavanone. METHODS Differentiated and polarized Caco-2 human intestinal epithelial cell lines were used for this purpose. KEY FINDINGS In our experimental conditions, quercetin and naringenin were poorly absorbed by Caco-2 cells. Quercetin was absorbed by passive diffusion and a pH-dependent mechanism mediated by the organic anion transporting protein B (OATP-B). It was not a multidrug resistance associated protein (MRP)1 substrate, but was substrate of the MRP2 efflux transporter and not P-glycoprotein (P-gp). Intestinal permeability from the apical to the basolateral side was higher for naringenin than for quercetin, which was partly explained by naringenin's physicochemical characteristics. Naringenin, partially absorbed by passive diffusion, was also an ATP-dependent transport substrate mediated by MRP1, but was not an OATP-B substrate. However, naringenin was secreted via active P-gp and MRP2 efflux transporters. CONCLUSIONS The contribution of ATP-dependent efflux transporters (MRP2 and P-gp) to the permeability of these compounds in the apical side could explain their low bioavailability. In conclusion, knowledge of the absorption mechanism of these two flavonoids was used to determine the intake level that has a beneficial effect on human health and their putative role in food-drug interactions.
Code Compression with Split Echo Instructions

Code density is often a critical issue in embedded computers, since the memory size of embedded systems is strictly limited. Echo instructions have been proposed as a method for reducing code size. This paper presents a new type of echo instruction, split echo, and evaluates an implementation of both split echo and traditional echo instructions on a MIPS R3000 based processor. Evaluation results show that memory requirement is reduced by 12% on average with small additional hardware cost.
Additive Effects of Radiation and Docetaxel on Murine SCCVII Tumors In Vivo: Special Reference to Changes in the Cell Cycle

Abstract Suzuki, M. , Nakamatsu, K. , Kanamori, S. , Masunaga, S. and Nishimura, Y. Additive Effects of Radiation and Docetaxel on Murine SCCVII Tumors In Vivo: Special Reference to Changes in the Cell Cycle. Radiat. Res. 159, 799–804 (2003). The purpose of the present study was to investigate the effects of a combination of docetaxel and irradiation in vivo with special reference to docetaxel-arrested G2/M-phase cells. At 24 and 48 h after intraperitoneal administration of docetaxel (90 mg/kg), tumor-bearing mice were irradiated with 60Co γ rays. Cell cycle distribution was analyzed by a DNA-Ki-67 double staining method using flow cytometry. An accumulation of cells in the G2/M phase of up to approximately 40% was observed 24 h after administration of docetaxel. Between 24 and 72 h, the percentage of cells arrested in G2/M phase that expressed Ki-67 decreased from 37.2% to 13.8%, in accordance with the increase in the Ki-67-negative G2/M-phase fraction. More than half of the cells arrested in G2/M phase lost their expression of Ki-67 protein between 24 and 72 h. The G1-phase fraction decreased from 28.4% to 8.6% at 24 h after docetaxel treatment; this remained unchanged at 72 h. These flow cytometry data suggested that docetaxel-arrested G2/M-phase cells did not enter the next cell cycle and were killed by docetaxel alone. Our data showed that arrest of cells in G2/M phase does not contribute to the synergism that has been reported for combinations of docetaxel and radiation in in vivo tumor models.