Miracle-dz/UniFAR-FTUs huggingface dataset:
Immunopathological Features Developing in the Mosquito Midgut after Feeding on Anopheles gambiae Mucin-1 / Interleukin-12 cDNA Immunized Mice

El intestino medio es el organo al cual pasa la sangre consumida por el mosquito y donde, mediante una membrana peritrofica secretada por el epitelio, esta sangre es mantenida durante la digestion y absorcion. El intestino del mosquito esta revestido por microvellosidades llenas de actina que son expuestas a las complejas condiciones en torno a la luz intestinal, tales como la abrasion producida por particulas de alimentos, hidrolasas digestivas y el ataque de patogenos y parasitos que son tomados en la sangre consumida. Estas microvellosidades se protegen de estos efectos mediante la matriz peritrofica, el glicocalix y las proteinas de mucina que revisten las superficies epiteliales. La inmunizacion con AgMUC1/IL-12 ADNc en ratones BALB/c ha demostrado ser util para matar los mosquitos cuando se alimentan de estos ratones. La mucina es una de las proteinas producidas en el intestino medio del mosquito despues de consumir sangre. La fina estructura del epitelio del intestino interactua con factores inmunes tales como anticuerpos o celulas inmunes es de especial importancia para interpretar los eventos tempranos en la interaccion entre el revestimiento del intestino medio y los componentes inmunologicos especificos presentes en la sangre de ratones BALB/c inmunizados con AgMUC1/IL-12 cDNA. Despues de observar mediante microscopias de luz, electronica de barrido y de transmision las caracteristicas de secciones del intestino medio del mosquito Anopheles gambiae alimentado de ratones BALB/c inmunizados con AgMUC1/IL-12 cDNA, mecanismos inmunes mediados por citotoxicidad celular dependiente de anticuerpos (ADCC) podrian ser los responsables de matar a los mosquitos. Los procesos necroticos y apoptoticos que pueden ser la causa de la muerte del mosquito tienen lugar en las celulas que recubren el epitelio del intestino medio.
GoetheShaker ? - Developing a Rating Score for Automated Evaluation of Cocktail Recipes

In this paper we present a method for automated evaluation of cocktail recipes. Based on three components, we created a measure to assess the quality of a cocktail: harmony, popularity and prole match. The harmony represents how dierent ingredients harmonize with each other. The popularity helps frequently used ingredients stabilizing the recipe. The prole match ensures that cocktail recipes are well formed.
Understanding the Trends in Learning Outcomes in Argentina, 2000 to 2012

This paper seeks to understand what drove the trends in learning outcomes in Argentina between 2000 and 2012, using data from four rounds of the Program for International Student Assessment. A year-specific education production function is estimated and its results used to decompose the changes in learning outcomes into changes in inputs, parameters, and residuals via microsimulations. Estimates of the production function show the importance of socioeconomic status, gender, school autonomy, and teacher qualifications to determine learning outcomes. Despite an important increase in the level of resources invested in public education, learning outcomes in public schools decreased vis-a-vis private schools. According to the results presented here, the increase in the number of teachers in the system, pushing the pupil-teacher ratio in Argentina to 11, had no effect on learning outcomes. The microsimulation further confirms that changes in the system’s ability to transform inputs into outcomes accounted for most of the changes in test scores. Overall, the study shows the ineffectiveness of input-based education policies to improve learning outcomes in Argentina.
Electroencephalogram Neurofeedback Treatment for Taiwanese Children with Attention Deficit Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is the most common neuropsychiatric disorder in children. Stimulant drugs treatment has been one of the major therapeutic options for children with ADHD. Roughly 34% of children are medication non-responders and many others are partial responders. Neurofeedback treatment is a promising alternative which is supported by western extensive peer-reviewed literature. However, there are limited empirical data of the effect of neurofeedback in Asian population. The purpose of the present study is to examine the effects of neurofeedback on the core symptoms and neuropsychological measures in Taiwanese children with ADHD who were partial responders to pharmacotherapy. Twenty-six children (7-12 years) with DSM-5 diagnosed ADHD entered this study. Subjects of neurofeedback group (N=13) received medication together with 20 sessions/ 8 weeks of neurofeedback training targeting on decreasing Theta brain wave of electroencephalogram. Control group children (N=13) received medication only. For the baseline and 8-week follow up assessments, all children received Continuous Performance test and their primary caregivers completed ADHD core symptoms rating scales. Significant improvements were noted on attention test and core ADHD symptoms measures for subjects who received add-on neurofeedback training as compared with the control group. The study supported the positive effect of neurofeedback training as add-on treatment for Taiwanese children with ADHD. Twenty sessions of neurofeedback can be beneficial in a short term follow up.
Digital Multimedia Design Integration Model based on Experience Design

The thought of experience design can create a digital media system environment that is in line with human life experience which can assist designers to plan tour experience for the users, and shape the digital media system environment with experience value. The objective of this study is to draw an effective design method through the experience design thinking and to apply it to the development of digital media system. Through the well-designed overall environment, the user's emotional experience can also be met. By way of the discussion of literature theory, consolidation of the expert interviews, and 14 case observations, this study summarizes the design principles applied to the integrated development of digital media systems. The results of this study sum up 12 design criteria and propose a set of feasibility and reference value of the design method for the relevant designer’s reference. The design principle gives design workers a clear design and implementation criteria to promote the designers (managers, executor, etc.) to have a clearer goal, enhance the design quality of digital media, and to create an environment that is focused on user’s feeling and experience.
Design and simulate cloud computing environment using cloudsim Ms

Cloud computing has been emerging as powerful computational architecture which will be a major technology in the development of the future Internet of Services. In order to save energy consumption we need to apply new energy-efficiency mechanism and observe its effects on a datacenter. As it is difficult to test new mechanism in real cloud computing environment and researchers often cannot reach the real cloud environment, simulation to model the mechanism and evaluate the results is necessary. Simulating a datacenter avoids spending time and effort to configure a real testing environment. This paper propose an extensible simulation framework called CloudSim which supports simulation, modelling of cloud computing and creation of one or more virtual machines(VMs) on a simulated node of a Data Center, jobs, and their mapping to suitable VMs, power to manage services and modeling of cloud infrastructure. Also manage your own mechanism in cloud computing. It also allows simulation of multiple Data Centers. IndexTerms—Cloud computing, Cloudsim, Datacenter,
MPRO-Spanish: development and experiments with a linguistic parser for Spanish texts

This paper describes the main features and present results of MPRO-Spanish, a parser for morphological and syntactic analysis of unrestricted Spanish text developed at the IAI1. This parser makes direct use of X-phrase structure rules to handle a variety of patterns from derivational morphology and syntactic structure. Both analyses, morphological and syntactic, are realised by two subsequent modules. One module analyses and disambiguates the source words at morphological level while the other consists of a series of programs and a deterministic, procedural and explicit grammar. The article explains the main features of MPRO and resumes some of the experiments on some of its applications, some of which still being implemented like the monolingual and bilingual term extraction while others need further work like indexing. The results and applications obtained so far with simple and relatively complex sentences give us grounds to believe in its reliability.
Covariability of Surface Wind and Stress Responses to Sea Surface Temperature Fronts

AbstractThe responses of surface wind and wind stress to spatial variations of sea surface temperature (SST) are investigated using satellite observations of the surface wind from the Quick Scatterometer (QuikSCAT) and SST from the Advanced Microwave Scanning Radiometer on the Advanced Microwave Scanning Radiometer for Earth Observing System (EOS) (AMSR-E) Aqua satellite. This analysis considers the 7-yr period June 2002–May 2009 during which both instruments were operating. Attention is focused in the Kuroshio, North and South Atlantic, and Agulhas Return Current regions. Since scatterometer wind stresses are computed solely as a nonlinear function of the scatterometer-derived 10-m equivalent neutral wind speed (ENW), qualitatively similar responses of the stress and ENW to SST are expected. However, the responses are found to be more complicated on the oceanic mesoscale. First, the stress and ENW are both approximately linearly related to SST, despite a nonlinear relationship between them. Second, the s.
Diffuse competition and continuous niche shifts in size-structured populations of predatory salamanders

Size-specific interactions between predators can affect both species population dynamics and the structure and biodiversity of communities they inhabit. Interactions between size-structured populations of predators, especially those with complex life-cycles, often change with resource-use changes driven by ontogenetic niche shifts. However, if resource use is determined largely by prey size, generalist predators may compete across a wider range of body sizes and life stages resulting in diffuse intra- and interspecific competition. We examined size- and stage-specific interactions between juvenile sirens (Siren intermedia) and adult newts (Notophthalmus viridescens dorsalis) in the context of previous experiments demonstrating competitive equality of larvae and strong effects of adult S. intermedia on adult N. viridescens. Competition between juvenile siren and adult newts was mutually negative and roughly symmetrical. Two S. intermedia reduced growth of three N. viridescens by 21%, while three N. virides.
Functional characterisation of Syndecan, a heparan sulphate proteoglycan, in Slit/Robo signalling

Syndecan (Sdc) is a type I transmembrane protein characterized by the presence of linear sugar chains called heparan sulphate glycosaminoglycans (HSGAGs) linked to its extracellular domain. Sdc was shown to be critical for the fidelity of Slit repellent signalling at the Drosophila midline where via its receptor Robo, Slit patterns the central nervous system (CNS) and the musculature. This study aimed at shedding some light on how Sdc functions in Slit/Robo signalling. Employing the UAS/GAL4 system, different sdc variants and chimeric transgenes were expressed in specific tissues in a sdc mutant background and tested for their rescue capability. Rescue was scored by the absence of ventral midline crossing of ipsilateral axons and ventral muscles. The in vivo rescue experiments proved that Drosophila Sdc is specifically required on the target tissue where it functions as a coreceptor with Robo and that Sdc has no function in Slit secretion or transport nor does it have an independent intracellular signalling activity. Furthermore, the results also support a model in which shedding of Sdc though not required for the fidelity of Slit repellent signalling could occur by the proteolytic activity of a serine protease which might function as a negative feedback system or might be required for the recycling of Robo receptor.
Effect of Z
 ataria multiflora
 Boiss Essential Oil and Grape Seed Extract on the Shelf Life of Raw Buffalo Patty and Fate of Inoculated L
 isteria monocytogenes

The present study was conducted to investigate the effect of Zataria multiflora Boiss essential oil (ZEO) and grape seed extract (GSE) on microbial and chemical changes in raw buffalo patty at a temperature of 8C. First, chemical composition and minimum inhibitory concentration of oil against Listeria monocytogenes were identified. Then, ZEO and GSE were added in raw buffalo patties and analyzed for spoilage microorganism count, lipid oxidation, pH, sensory attributes and inoculated L.monocytogenes survival at 8C for 9 days. Results revealed that samples containing 0.1 ZEO+0.2 GSE showed significant decrease in the growth of all tested microbial groups as well as the most decrease in the level of lipid oxidation at the end of storage period. Control and samples with 0.1 ZEO were the most preferred samples by sensory panelist, indicating that ZEO and GSE can be practically applied in food systems especially in meat in order to extend the shelf life. Practical Applications: Buffalo meat is highly prone to microbial and chemical spoilage as they are rich in essential nutrients and putrefying in nature. The adverse effects of various chemical preservatives caused to attract the consumer's attention to natural alternatives. Therefore, in order to increase the shelf life and quality characteristics of meat, new processing technologies and new ingredient systems that are associated with natural and organic foods are applied. These results demonstrate the potential combined use of grape seed extract and Zataria multiflora Boiss essential oil to the meat industry in the development of novel healthy meat products with improved shelf life and superior product quality. © 2015 Wiley Periodicals, Inc.
On Less Conservative Stability Criteria for Neural Networks with Time-Varying Delays Utilizing Wirtinger-Based Integral Inequality

This paper investigates the problem of stability analysis for neural networks with time-varying delays. By utilizing the Wirtinger-based integral inequality and constructing a suitable augmented Lyapunov-Krasovskii functional, two less conservative delay-dependent criteria to guarantee the asymptotic stability of the concerned networks are derived in terms of linear matrix inequalities (LMIs). Three numerical examples are included to explain the superiority of the proposed methods by comparing maximum delay bounds with the recent results published in other literature.
hosphorus storage dynamics and adsorption characteristics for ediment from a drinking water source reservoir and its relation with ediment compositions

Water and sediment samples were collected from a representative drinking water source reservoir to investigate the nutrient spatial distributions, phosphorus storage, adsorption features and its relation with sediment compositions. Monitored water TN, TP concentrations, sediment pH values exhibited a gradual decrease trend from the upstream to the downstream. Sediment AlT content (total aluminum oxides) was 2–4 times higher than FeT (total iron oxides) which mainly comprised with Fed (free iron
Assigning tie points to a generalised building model for UAS image orientation

Abstract. This paper addresses the integration of a building model into the pose estimation of image sequences. Images are captured by an Unmanned Aerial System (UAS) equipped with a camera flying in between buildings. Two approaches to assign tie points to a generalised building model in object space are presented. A direct approach is based on the distances between the object coordinates of tie points and planes of the building model. An indirect approach first finds planes within the tie point cloud that are subsequently matched to model planes; finally based on these matches, tie points are assigned to model planes. For both cases, the assignments are used in a hybrid bundle adjustment to refine the poses (image orientations). Experimental results for an image sequence demonstrate improvements in comparison to an adjustment without the building model. Differences and limitations of the two approaches for point-plane assignment are discussed – in the experiments they perform similar with respect to estimated standard deviations of tie points.
Birefringence study of the irreversible behavior of the incommensurate phase of quartz: effects of chemical impurities

A systematic study of the variations of the irreversible properties of the incommensurate phase of quartz has been performed by birefringence measurements in 9 samples (either synthetic or natural) of various compositions determined by chemical analysis and infrared spectroscopy. The shift of the α-β transition temperature for large impurity concentrations has been verified. The properties of the incommensurate phase are very sensitive to small changes of impurity contents: a global hysteresis going from 10 to 220 mK has been correlated to the OH infrared absorption. Time dependent pinning steps and memory effects have been observed showing the importance of mobile impurities. Finally a regime of discontinuous variation of physical properties appears for slow rate of temperature variations. Thes Une etude systematique des proprietes irreversibles de la phase incommensurable du quartz a ete faite par des mesures de birefringence sur 9 echantillons (synthetiques ou naturels) de differentes compositions, determinees par analyse chimique et spectroscopie infrarouge. Les decalages de la temperature de la transition α-β, produits par des concentrations importantes d'impuretes ont ete mesures. Les proprietes de la phase incommensurable sont tres sensibles a la presence de faibles taux d'impuretes: des hysteresis globales variant de 10 a 220 mK, ont ete mesurees et une correlation avec l'absorption infrarouge due aux liaisons OH a ete trouvee. Des effets dependant du temps tels que des marches d'accrochages et des effets memoires ont ete observes, montrant l'importance des defauts mobiles. Enfin, un regime de variations discontinues des proprietes physiques apparait pour les petites vitesses de variation de la temperature. Les resultats de ces experiences ont ete compares a diverses predictions theoriques, telles que celles de la theorie des Ondes de Densite des Defauts dues a la diffusion des impuretes mobiles
Influence of organic waste and inorganic nitrogen source on biomass productivity of Scenedesmus and Chlorococcum sp.

Algae gaining the more attention in the recent years in order to supplement the futuristic demand of fuel requirement because of its unique feature like high productivity, short duration and higher fatty acids content. However algal culturing for large-scale production is limited due to many technical and engineering challenges. One of the main constraints for large-scale biomass production is the nonavailability of cost effective and affordable growth medium for open pond condition. In order to overcome this lacuna, the present study was carried out to find out the suitable cost effective growth medium using locally available resources. Farm Yard Manure an easily available organic waste yet, rich in nutrients and used for agriculture over the generations. FYM coupled with inorganic nitrogen source like urea was found to be better alternative to the synthetic growth medium, which may make wider acceptability at farmers’ field for large-scale algal mass production. The present study reveals that FYM extract of 50% supplemented with 0.1% Urea was performing better for algal biomass growth in outdoor open pond condition. Copyright © 2011 International Energy and Environment Foundation All rights reserved.
Antibacterial activities and toxicological potentials of crude ethanolic extracts of Euphorbia hirta

Leaves of Euphorbia hirta used in traditional medicine for the treatments of boils, wounds and control of diarrhoea and dysentery were extracted by maceration in ethanol. The agar diffusion method was used to determine the antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi and Bacillus subtilis at different concentrations while toxicological studies was carried out through intraperitoneal injection of albino rat with varying concentrations of the extract. Antibacterial sensitivity test indicated that the extract inhibited the growth of S. aureus, E. coli, B. subtilis and P. aeruginosa to varying degrees while S. typhi was not affected. Minimum inhibitory concentration (MIC), of the extract against E. coli, S aureus, P. aeruginosa and B. subtilis were 58.09, 22.55, 57.64 and 74.61 mg/ml respectively. Hematological analyses revealed that there was no significant difference (p = 0.05) between the total red blood cells (RBC), white blood cells (WBC), hemoglobin (Hb) and mean corpuscular hemoglobin concentration (MCHC) values of the rats used as control and those treated with the different concentrations of the extract. Also, the erythrocyte sedimentation rate (ESR) and mean corpuscular volume (MCV) values were significantly different at certain concentrations of the extract administered which indicates that the plant extract is heamatologically not toxic to rats. The plant extract was found to contain tannins, alkaloids and flavonoids which may be responsible for its antimicrobial properties. The results justify the traditional use of the plant in the treatment of sores, boils, wounds and control of dysentery and diarrhoea.
Structural and biochemical investigation of Metallo-β-lactamases : insights into antibiotic binding sites

Two files, one with the articles and one without the articles are submitted in Munin. The file without the articles can be publically available after the PhD defence. The file with the articles shall not be publically available in Munin. The following text should be added: The articles of this thesis are not available in Munin: 1. Pardha Saradhi Borra, Hanna-Kirsti S. Leiros, Rafi Ahmad, James Spencer, Ingar Leiros, Timothy R. Walsh, Arnfinn Sundsfjord, and Orjan Samuelsen. Structural and Computational Investigations of VIM-7: Insights into the Substrate Specificity of VIM Metallo-β-Lactamases, published in Journal of Molecular Biology 2011:411:174-189. Available at: http://dx.doi. org/10.1016/j.jmb. 2011.05. 035 2. Allaaeddin El Salabi, Pardha Saradhi Borra, Mark A. Toleman, Orjan Samuelsen, and Timothy R. Walsh. Genetic and Biochemical Characterization of a Novel Metallo-β-Lactamase, TMB-1, from an Achromobacter xylosoxidans Strain Isolated in Tripoli, Libya, published in Antimicrobial Agents and Chemotherapy 2012:56:2241-2245. Available at: http://dx.doi. org/10.1128/AAC.05640-11 3. Hanna-Kirsti S. Leiros, Pardha S. Borra, Bjorn Olav Brandsdal, Kine Susann Waade Edwardsen, James Spencer, Timothy R. Walsh, and Orjan Samuelsen. Crystal Structure of the Mobile Metallo-β-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the Role of Gln157, Antimicrobial Agents and Chemotherapy 2012 Jun. 4 Epub. ahead of print. 4. Pardha S. Borra, Orjan Samuelsen, Marit Sjo Lorentsen, and Hanna-Kirsti S. Leiros. Three dimensional structure of the subclass B1 mobile metallo-β-lactamase GIM-1 from Pseudomonas aeruginosa, manuscript in preparation