Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards provisioning of SDN/NFV-based security enablers for integrated protection of IoT systems

Nowadays the adoption of IoT solutions is gaining high momentum in several fields, including energy, home and environment monitoring, transportation, and manufacturing. However, cybersecurity attacks to low-cost end-user devices can severely undermine the expected deployment of IoT solutions in a broad range of scenarios. To face these challenges, emerging software-based networking features can introduce new security enablers, providing further scalability and flexibility required to cope with massive IoT. In this paper, we present a novel framework aiming to exploit SDN/NFV-based security features and devise new efficient integration with existing IoT security approaches. The potential benefits of the proposed framework is validated in two case studies. Finally, a feasibility study is presented, accounting for potential interactions with open-source SDN/NFV projects and relevant standardization activities.
High voltage amplifier

In typical ion trap experiments, two or more electrodes are drive by sine waves. Their amplitude and frequency determine the atomic mass (amu) of the particles to be trapped. Thus, by sweeping one of those two parameters, a continuous mass-to-charge ratio of the sample can be obtained. Frequency sweep is preferred because in the voltage sweep, the higher the mass measured, the less resolution one gets. Frequency sweeps are limited by the signal generators available. For heavier organic molecules, peak-to-peak voltages as high as 1000 volts and frequencies up to 100 kHz are desirable. Unfortunately there are not too many instruments that can fulfill this task. This paper describes the design, construction and testing of a high voltage amplifier created specifically for this kind of experiment The outcome is a general purpose amplifier that can deliver up to 100 mA of current at 1000 V peak-to-peak, from DC to 100 kHz.
Vitamin D-Fortified Bread Is as Effective as Supplement in Improving Vitamin D Status: A Randomized Clinical Trial.

CONTEXT Bread can potentially be a suitable vehicle for fortification with vitamin D. OBJECTIVE This study was undertaken to evaluate the following: 1) the bioavailability of vitamin D from the fortified Iranian bread and 2) the possible effects of daily consumption of the fortified bread on certain health aspects. DESIGN, SETTING, AND PARTICIPANTS This was a randomized, double-blind, placebo-controlled trial conducted over 8 weeks in 90 healthy subjects aged 20-60 years. INTERVENTION Subjects were randomly allocated to one of three groups: 1) fortified bread (FP; 50 g bread fortified with 25 μg vitamin D3 plus placebo daily; n = 30); 2) supplement (SP; 50 g plain bread plus 25 μg vitamin D supplement daily; n = 30); and 3) control (CP; 50 g plain bread plus placebo daily; n = 30). OUTCOME MEASURES Initial and final anthropometric and biochemical assessments were performed. RESULTS The within-group changes of serum 25-hydroxyvitamin D concentrations were 39.0 ± 22.6 (P < .001), 28.9 ± 31.2 (P < .001), and -9.2 ± 12.3 nmol/L in the FP, SP, and CP groups, respectively. Only in FP and SP groups, serum intact PTH concentrations decreased approximately 13.5% and 14.5%, respectively. Visceral fat also showed a significant decrement in FP (-1.05% ± 1.4%; P ≤ .001) and SP (-0.96% ± 1.7%; P = .006). Serum low-density lipoprotein cholesterol concentration showed a within-group reduction in FP (-10.4 ± 11.2 mg/dL; P < .001) and an insignificant decrement in SP (-6.6 ± 20.2 mg/dL; P = .083). Serum high-density lipoprotein increased in both vitamin D-supplemented groups (FP: 9.7 ± 7.6 vs SP: 5.7 ± 6.7 mg/dL; P < .001). CONCLUSION Vitamin D-fortified bread could be potentially effective in raising circulating 25-hydroxyvitamin D levels of the population to nearly adequate levels.
Element pattern analysis of wide-band arrays with the help of a finite-by-infinite array approach

Strong couplings characterizing wide-band arrays lead to a wide variation of the active element patterns in finite arrays. We show how finite-by-infinite array simulation results and infinite-array solutions can be combined to estimate the element patterns in arrays finite in both directions. The accuracy of the method is discussed for the case of dual-polarized arrays of tapered-slot antennas, with electrically interconnected elements. For elements located in the array corners, a second correction procedure, based on results obtained for small arrays, is presented.
A quick and simple method for detecting subjects with abnormal genetic background in case‐control samples

It is important that case‐control samples be drawn from a genetically homogeneous population in order to avoid artefactual false positive results and to enhance power to detect disease mutations and markers in linkage disequilibrium with them. Tests which simply compare overall marker allele frequencies between cases and controls will fail to identify a relatively small number of subjects drawn from a different genetic background who could usefully be discarded from the sample. Such subjects can be identified using multilocus tests, but previously described tests have been unnecessarily complex and cumbersome for this simple application. We describe a straightforward test, implemented in the CHECKHET program, which uses a measure of genetic difference and permutation procedures to rapidly identify such subjects using genotypes from multiple unlinked markers. It seems to perform reasonably well on simulated data, and with real data appears to identify two abnormal subjects within a case‐control sample. We recommend that such tests be routinely applied to case‐control samples once sufficient numbers of markers have been genotyped within them.
Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine.

Immunoblotting analysis of human liver microsome preparations revealed that human cytochrome P-450 PCN1 (hPCN1, Mr approximately 52,000) was expressed in each of 40 individual specimens examined. In about 10-20% of the livers, an immunologically related protein having a lower electrophoretic mobility (Mr approximately 52,500) was also detected. A single liver was found that expressed only the lower mobility protein, designated hPCN3, and RNA isolated from this liver was used to construct a lambda gt11 library. The library was screened with an hPCN1 cDNA probe resulting in the isolation of a unique full-length cDNA that was sequenced and shown to encode hPCN3. The deduced amino acid sequence of this cDNA contained 502 residues, a calculated molecular mass of 57,115 daltons, and displayed 84% similarity with hPCN1. The deduced amino-terminal sequence of hPCN3 was identical to that of HFLa, a major cytochrome P-450 expressed in human fetal liver that is immunologically cross-reactive with several family III cytochrome P-450s. hPCN1 and hPCN3 cDNAs were expressed in Hep G2 cells using a vaccinia virus expression system and shown to encode active enzymes, both characterized by reduced CO-binding spectra with lambda max at 450 nm. Enzymatic analysis revealed that both cytochrome P-450s were similarly active in catalyzing oxidation of the calcium channel blocking drug nifedipine. Both enzymes also catalyzed 6 beta-hydroxylation of the steroid hormones testosterone, progesterone, and androstenedione, although hPCN1 exhibited several-fold higher expressed activity than hPCN3. Several minor oxidation products of these steroids (e.g. 15 beta-hydroxytestosterone), comprising up to approximately 20% of the total metabolites, were formed by hPCN1 but not hPCN3, indicating that hPCN3 is a more highly regiospecific monooxygenase catalyst with steroid substrates. Clear differences were also detected in their catalytic activities toward the immunosuppressive drug cyclosporine, with two hydroxylated metabolites (M1 and M17) and one demethylated metabolite (M21) formed by hPCN1 but only one metabolite (M1) formed by hPCN3. These studies establish that hPCN3 is a newly described cytochrome P-450 that is differentially expressed in the adult human population and that has overlapping substrate specificity compared to hPCN1 for metabolism of steroid and drug substrates.
The effects of bilateral removal of the carotid bodies and denervation of the carotid sinuses in two human subjects.

The subjects were two hospital patients with long-established bronchial asthma. Their histories and clinical condition have been described elsewhere (Wood, Frankland & Eastcott, 1965). The clinical details are largely irrelevant to the present paper since each subject was tested before operation and thus provided control observations. Subject A (patient 2 of Wood et al. 1965) was a woman of 53 and subject B (patient 3 of Wood et al. 1965) was a man of 44. A box bag respirator (Donald & Christie, 1949) was used to administer gas mixtures for periods of up to 4 min each and to record tidal volume and respiratory frequency. The gas mixtures were saturated with water vapour at room temperature and had the following composition: room air, 100% oxygen, 10% oxygen in nitrogen, 3% carbon dioxide in air and 6% carbon dioxide in air. 10% oxygen was usually administered twice on each occasion. On some occasions arterial oxygen saturation was recorded with an Atlas ear oximeter which was calibrated against samples of arterial blood analysed by manometric Van Slyke estimations and was accurate to within + 4 %. Arterial blood pressure and pulse rate were measured at frequent intervals by auscultation and palpation respectively or by a Sanborn pressure transducer and recorder through a needle in the brachial artery. The frequency response was accurate from 0.5 to 15 c/s. Passive changes in posture were produced by tilting the subject on an Eve rocker which had been modified to allow a vertical position. Valsalva mannsuvres were performed by the subject blowing against a mercury column.
Hmong Means Free: Life in Laos and America

Illustrations Preface Acknowledgements Personal and Place Names Introduction: The Hmong Experience in Asia and the United States 1. The Xiong Family of Goleta 2. The Xiong Family of Lompoc 3. The Fang Family of San Diego 4. The Tcha Family of Fresno 5. The Maua Family of Sanger Notes to the Introduction Selected Bibliography Notes on the Editor and Transcribers/Translators
Two Histone Marks Establish the Inner Centromere and Chromosome Bi-Orientation

Location, Location, Location Cell division is orchestrated by a complex signaling pathway that ensures the correct segregation of newly replicated chromosomes to the two daughter cells. The pathway is controlled in part by restricting the activity of critical regulators to specific subcellular locations. For example, the chromosomal passenger complex (CPC) is recruited to chromosomes during mitosis where it oversees kinetochore activity and cytokinesis (see Perspective by Musacchio). Wang et al. (p. 231, published online 12 August), Kelly et al. (p. 235, published online 12 August), and Yamagishi et al. (p. 239) now show that the phosphorylation of the chromatin protein, histone H3, acts to bring the CPC to chromosomes, thereby activating its aurora B kinase subunit. The Survivin subunit of CPC binds specifically to phosphorylated H3, with the phosphorylation at centromeres being carried out by the mitosis-specific kinase, haspin. Furthermore, Bub1 phosphorylation of histone H2A recruits shugoshin, a centromeric CPC adapter. Thus, these two histone marks in combination define the inner centromere. Phosphorylation of histones recruits proteins critical for the segregation of chromosomes during cell division. For proper partitioning of chromosomes in mitosis, the chromosomal passenger complex (CPC) including Aurora B and survivin must be localized at the center of paired kinetochores, at the site called the inner centromere. It is largely unknown what defines the inner centromere and how the CPC is targeted to this site. Here, we show that the phosphorylation of histone H3–threonine 3 (H3-pT3) mediated by Haspin cooperates with Bub1-mediated histone 2A–serine 121 (H2A-S121) phosphorylation in targeting the CPC to the inner centromere in fission yeast and human cells. H3-pT3 promotes nucleosome binding of survivin, whereas phosphorylated H2A-S121 facilitates the binding of shugoshin, the centromeric CPC adaptor. Haspin colocalizes with cohesin by associating with Pds5, whereas Bub1 localizes at kinetochores. Thus, the inner centromere is defined by intersection of two histone kinases.
A 6,000 Year Old Red Abalone Midden from Otter Point, San Miguel Island, California

For decades, researchers have been interested in archaeological sites on California's Channel Islands that contain large concentrations of red abalone (Haliotis rufescens) shells. Known as red abalone middens and dated to between about 7500 and 3500 years ago, these sites have been used to understand broad subsistence patterns, provide chrono-stratigraphic control, and investigate past environmental changes in the region. Most detailed studies have focused on red abalone middens from Santa Cruz Island, with comparatively limited data from other islands. Analysis of a red abalone midden sample excavated from a large dune site on San Miguel Island illustrates the diversity of the red abalone site type and associated human behaviors. Rapid changes in the primary midden constituents, from California mussels (Mytilus californianus) and sea mammals to red abalones, demonstrate the complexities of differentiating between the effects of environmental change, human food choices, and ecological changes associated with human impacts on local environments.
Exemplary nursing leadership is central to improving care of the dying.

The recent 76th World Health Assembly has called upon the global community to focus on strengthening palliative care as a component of integrated care throughout the life course. The Resolution represents a global commitment from the 194 member states of the World Health Organization to implement palliative care policies and to move from fragmented efforts towards worldwide collaboration (Sixty-seventh World Health Assembly, 2014). Transforming this vision into reality, requires a commitment from policy makers, non-government organisations, clinicians and consumers to work collaboratively to address these known gaps. In this editorial we contend that the World Health Assembly vision for palliative care can be realised if nurses, within all levels of the health care system apply the ‘Five Practices of Exemplary Leadership’, and inspire a shared vision; challenge the process; enable others to act; model the way; and encourage the heart (Kouzes & Posner 2012).
Auctions with Flexible Entry Fees

There is by now a large literature arguing that auctions with a variety of after-market interactions may not yield an efficient allocation of the objects for sale, especially when the bidders impose strong negative externalities upon each other. This paper argues that these inefficiencies can be avoided by asking bidders prior to the auction to submit any public payment they would like to make. These payments, so-called flexible entry fees, do not affect the allocation decision of the auctioneer. We show that auctions with flexible entry fees have a fully revealing equilibrium where bidders signal their type before the auction itself takes place.
Supercritical Fluid Extracts of Rosemary Leaves Exhibit Potent Anti-Inflammation and Anti-Tumor Effects

Supercritical fluid SF-CO2 treatment of Rosemarinus officinalis L. fresh leaves under optimum conditions (80 °C at 5,000 psi) yielded 5.3% of extract supercritical fluid extraction (SFE)-80, in which five major active principles were identified by liquid chromatography/mass spectrometry (LC/MS), viz., rosmarinic acid, carnosol, 12-methoxycarnosic acid, carnosic acid, and methyl carnosate. Total phenolic content was 155.8 mg/ gallic acid equivalent (GAE)/g in SFE-80, which showed 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging of 81.86% at 0.01 mg/ml. When treated in RAW 264.7, apparent dose-dependent NO inhibition occurred at dosages of 1.56 to 6.25 μg/ml, and more drastically at 12.5 and 25 μg/ml. At 0.5 to 5.0 μg/ml, SFE-80 exhibited dose-dependent viability suppression and significant tumor necrosis factor alpha (TNF-α) production in Hep 3B, whereas no effect was found in Chang liver cells. Furthermore, no effect was observed in RAW 264.7 at dosages of 3.13 to 25 μg/ml, indicating that SFE-80 exhibited a noncytotoxic character. Conclusively, rosemary can be considered an herbal anti-inflammatory and anti-tumor agent.
Analyse chronologique des traces journalisées d’un guide d’étude pour apprentissage autonome

Les environnements informatiques pour l'apprentissage humain (EIAH) et le Web multiplient les opportunites d’apprentissage autonome. Les exerciseurs jouent un role important pour ce type d’apprentissage car ils fournissent un encadre-ment essentiel a la demarche d’etude d’un cours, pour la preparation d’un exa-men et pour l’obtention d’un diplome. Un guide d’etude en ligne comprenant un exerciseur est ici presente. Il a ete developpe pour l’apprentissage de mathema-tiques pre-universitaire dans une ecole de genie. Cette application a ete de-ployee en mode experimental durant un trimestre. Une majorite d’utilisateurs l’ont utilise brievement, alors que quelques autres l’ont utilise plus intensivement. Des traces journalisees detaillees permettent d’obtenir un portrait de leur utilisa-tion. Nous presentons differentes analyses descriptives de ces traces et dega-geons quatre profils d’utilisation. Nous decrivons une methode d’analyse basee sur les sequences des activites des utilisateurs qui permet de visualiser l’utilisation dans le temps. L’analyse des sequences est appliquee pour caracte-riser les niveaux d’activites selon une perspective chronologique.
The Linguistic Annotation System of the Stockholm - Umeå Corpus Project

In the Stockholm Ume~ Corpus project, SUC, we have developed and applied a system for representing lexical and morphological information about word forms in unrestricted text. Our poster presents results and experiences from the application of the system to 300,000 word forms, a subpart of a larger corpus. The application of the system is carried out in two steps, an automatic lexical look up followed by homograph separation, which is done partly automatically, partly manually. Lexical and morphological analysis and disambiguation of Swedish is a rather complicated task, a fact which should hold for several other languages as well. Below a sample text is given, showing both the amount of information that has to be specified for each word form and the degree of ambiguity to he resolved.
Effect of exposure and withdrawal of 900-MHz-electromagnetic waves on brain, kidney and liver oxidative stress and some biochemical parameters in male rats

Abstract Increasing use of mobile phones in daily life with increasing adverse effects of electromagnetic radiation (EMR), emitted from mobile on some physiological processes, cause many concerns about their effects on human health. Therefore, this work was designed to study the effects of exposure to mobile phone emits 900-MHz EMR on the brain, liver and kidney of male albino rats. Thirty male adult rats were randomly divided into four groups (10 each) as follows: control group (rats without exposure to EMR), exposure group (exposed to 900-MHz EMR for 1 h/d for 60 d) and withdrawal group (exposed to 900-MHz electromagnetic wave for 1 h/d for 60 d then left for 30 d without exposure). EMR emitted from mobile phone led to a significant increase in malondialdehyde (MDA) levels and significant decrease total antioxidant capacity (TAC) levels in brain, liver and kidneys tissues. The sera activity of alanine transaminase (ALT), aspartate aminotransferase (AST), urea, creatinine and corticosterone were significantly increased (p < 0.05), while serum catecholamines were insignificantly higher in the exposed rats. These alterations were corrected by withdrawal. In conclusion, electromagnetic field emitting from mobile phone might produce impairments in some biochemicals changes and oxidative stress in brain, liver and renal tissue of albino rats. These alterations were corrected by withdrawal.
The antihypertensive efficacy of losartan and amlodipine assessed with office and ambulatory blood pressure monitoring. Canadian Cozaar Hyzaar Amlodipine Trial Study Group.

BACKGROUND Losartan potassium is a recently marketed angiotensin II receptor antagonist. Previous studies have suggested that its full antihypertensive efficacy may be delayed for up to 12 weeks. The authors compared the antihypertensive efficacy and tolerability of losartan at 6 and 12 weeks with those of amlodipine besylate, a commonly used calcium antagonist. METHODS This multicentre, randomized, double-blind clinical trial studied 302 patients with mild or moderate hypertension in 1995. Of the 302, 97 also underwent ambulatory blood pressure monitoring (ABPM). After a 4-week placebo run-in period, the patients were randomly assigned to group A, B or C for 12 weeks. Those in groups A and B began treatment with losartan at 50mg/d, and those in group C began with amlodipine at 5 mg/d. If the blood pressure remained uncontrolled after 6 weeks, subjects in group A had their losartan dose doubled (to 100 mg/d), those in group B were given hydrochlorothiazide (12.5 mg/d) in addition to the losartan, which remained at 50 mg/d, and patients in group C had their amlodipine dose doubled (to 10 mg/d). RESULTS At 12 weeks all 3 regimens reduced office-recorded diastolic blood pressure (DBP) with the patient sitting. The mean reduction in group A was 8.7 mm Hg (95% confidence interval [CI] 7.3 to 10.1) (p < 0.001), in group B 12.5 mm Hg (95% CI 11.0 to 14.0) (p < 0.001) and in group C 12.9 mm Hg (95% CI 11.4 to 14.5) (p < 0.001). Losartan alone lowered sitting DBP to a lesser degree than the other 2 treatments (p < 0.01). In contrast, ABPM readings, whether 24-hour, daytime or nighttime, were not different among the regimens. Comparison of the results at 6 weeks yielded similar findings. Adverse effects were uncommon and were not different among the groups, with the exception of ankle edema, which was more frequent in group C. INTERPRETATION Losartan alone reduces both office and ABPM readings. The observed changes in office-recorded sitting DBP suggest that losartan is less effective than amlodipine or the combination of losartan and hydrochlorothiazide, but ABPM did not confirm this difference. Perhaps changes in office readings measure different attributes of a drug than does ABPM.