Miracle-dz/UniFAR-FTUs huggingface dataset:
Employment projections through the lens of education and training

Students and career changers want to know what preparation is needed for entry into various careers or, alternatively, what types of career opportunities may be available for a given level of preparation. The counselors, teachers, parents, and others who assist the students also need this information. To better meet this need, the Bureau of Labor Statistics (BLS) has introduced a new set of education and training categories to depict the preparation that individuals need to enter and to become competent in specific occupations.
Increased IGF mRNA in human skeletal muscle after creatine supplementation.

PURPOSE We hypothesized that creatine supplementation would facilitate muscle anabolism by increasing the expression of growth factors and the phosphorylation of anabolic signaling molecules; we therefore tested the responses of mRNA for IGF-I and IGF-II and the phosphorylation state of components of anabolic signaling pathways p70(s6k) and 4E-BP1 to a bout of high-intensity resistance exercise after 5 d of creatine supplementation. METHODS In a double-blind cross-over design, muscle biopsies were taken from the m. vastus lateralis at rest and 3 and 24 h postexercise in subjects who had taken creatine or placebo for 5 d (21 g x d(-1)). For the first 3 h postexercise, the subjects were fed with a drink containing maltodextrin (0.3 g x kg(-1) body weight x h(-1)) and protein (0.08 g x kg(-1) body weight x h(-1)). RESULTS After creatine supplementation, resting muscle expressed more mRNA for IGF-I (+30%, P < 0.05) and IGF-II (+40%, P = 0.054). Exercise caused an increase by 3 h postexercise in IGF-I (+24%, P < 0.05) and IGF-II (+48%, P < 0.05) and by 24 h postexercise in IGF-I (+29%, P < 0.05), but this effect was not potentiated by creatine supplementation. The phosphorylation states of p70(s6k) and 4E-BP1 were not affected by creatine at rest; phosphorylation of both increased (150-400%, P < 0.05) to similar levels under placebo and creatine conditions at 3 h postexercise plus feeding. However, the phosphorylation state of 4E-BP1 was higher in the creatine versus placebo condition at 24 h postexercise. CONCLUSION The increase in lean body mass often reported after creatine supplementation could be mediated by signaling pathway(s) involving IGF and 4E-BP1.
Visualization and analysis of user behaviour patterns for multimedia content view in social networks

Online social networks have become the major source of information and entertainment for millions of users due to the tremendous increase of the accessibility options. Mobile internet has revolutionized the users to access social networking sites with ease and also allows to various social multimedia content anytime, anywhere and on behalf of any identity. This makes the analysis of user interactions and behaviours more complicated. This paper focuses on developing a visualization model named as Social Pattern Clustering WebClickviz (SPC-WebClickviz) for better analysis of the social user behaviour especially the multimedia access. This proposed model visualizes the social networking data based on user activities and then clusters them into specified groups. As the clustering is done for the multimedia content view, the Correlation clustering method has been introduced to group the user activities of multimedia access. Spearman's rank correlation coefficient is utilized as the correlation factor for the clustering. The clustering results are utilized by the organizations to produce the closely related products for the customer's intentions. It also aids in the multimedia developers to provide with content that serializes the users' intentions so that they can generate more traffic to their own websites through the common social networking sites.
Hyponatremia in hospitalized cancer patients and its impact on clinical outcomes.

BACKGROUND Hyponatremia is the most common electrolyte abnormality in clinical practice, yet little is known about its frequency in patients with cancer or its impact on their clinical outcomes. STUDY DESIGN Retrospective analysis of prospectively collected data. SETTING & PARTICIPANTS Patients with cancer admitted to the University of Texas M.D. Anderson Cancer Center in 2006 for 3 months. PREDICTOR Serum sodium levels categorized as eunatremia (serum sodium, 135-147 mEq/L) and mild (134-130 mEq/L), moderate (129-120 mEq/L), and severe (<120 mEq/L) hyponatremia. OUTCOMES (1) Length of hospital stay and (2) 90-day mortality. RESULTS In 4,702 admissions in 3,357 patients with cancer, hyponatremia (serum sodium <135 mEq/L) was noted in 47% of admissions. It was mild in 36%, moderate in 10%, and severe in 1%. Hyponatremia was acquired during the hospital stay in 24%. Using the first admission data, mean length of stay was 5.6 ± 5.0 days for patients with eunatremia and 9.9 ± 9.2, 13.0 ± 14.1, and 11.5 ± 12.6 days for those with mild, moderate, and severe hyponatremia, respectively. The respective HRs in the multivariate Cox model for longer hospital stay, using patients with eunatremia as reference, were 1.92 (95% CI, 1.75-2.13; P < 0.01), 2.94 (95% CI, 2.56-3.45; P < 0.01), and 2.32 (95% CI, 1.32-4.00; P = 0.01). 283 (8.4%) deaths occurred during 90 days, and in the multivariate model, the respective HRs for 90-day mortality for mild, moderate, and severe hyponatremia were 2.04 (95% CI, 1.42-2.91; P < 0.01); 4.74 (95% CI, 3.21-7.01; P < 0.01), and 3.46 (95% CI, 1.05-11.44; P = 0.04). These findings were consistent when analyses were repeated with sodium levels in tertiles. LIMITATIONS Observational study, retrospective, inability to adjust for all comorbid conditions. CONCLUSION Hyponatremia in patients with cancer is associated with longer hospital stay and higher mortality. Whether long-term correction of hyponatremia would improve these outcomes remains to be determined.
The effect of contextual variety on the practice, retention, and transfer of an applied motor skill.

Laboratory research in motor learning has consistently demonstrated higher retention and/or transfer when practice occurs under conditions of high contextual variety (e.g., Lee & Magill, 1983; Newell & Shapiro, 1976; Shea & Morgan, 1979;). In the present study, an attempt was made to determine whether a contextual variety effect could be demonstrated in a standard physical education instructional setting. During practice trials on the long and short badminton serves, male and female subjects performed under either blocked (i.e., all trials of one serve followed by all trials of the other) or varied (i.e., alternating trials of long and short serves) conditions. Retention and transfer tests (i.e., using the service area opposite that employed during the practice phase) were administered at the end of the badminton unit. Although little difference was observed in the performance of the two groups during practice, alternating-trial subjects demonstrated significantly higher retention of the short serve and significantly higher transfer of both serves than blocked-trial subjects. The performance of male and female subjects was not differentially influenced by practice structure conditions. It was concluded that a practice schedule that requires performers to change their plan of action from trial to trial may facilitate the retention and transfer of motor skills in applied instructional settings.
The Local Economic Impact of a Large Research University: Evidence from UC Merced

In this paper, I estimate the short‐run economic effects of the opening of The University of California, Merced in 2005 by comparing Merced with a counterfactual constructed by the synthetic control method. During the period 2005–2014, the opening of the campus has increased local employment by 13%, mainly in nontraded industries, such as the service sector. These findings suggest that a large research university could bring immediate benefits to the local economy because of its large demand from students and employees. (JEL J24, O18, R11)
The Calmodulin-Nitric Oxide Synthase Interaction

The neuronal isoform of nitric oxide synthase (nNOS) requires calmodulin for nitric oxide producing activity. Calmodulin functions as a molecular switch, allowing electron transport from the carboxyl-terminal reductase domain of nitric oxide synthase to its heme-containing amino-terminal domain. Available evidence suggests that calmodulin binds to a site between the two domains of nNOS, but it is not known how calmodulin then executes its switch function. To study the calmodulin-nNOS interaction, we created a series of chimeras between calmodulin and cardiac troponin C (cTnC, a homologue of calmodulin that does not activate nNOS). Although a few chimeras showed good ability to activate nNOS, most failed to activate. A subset of the inactive chimeras retained the ability to bind to nNOS and therefore functioned as potent competitive inhibitors of nNOS activation by calmodulin (CaM). The observed inhibition was additive with the arginine antagonists N-monomethyl-L-arginine and 7-nitroindazole, indicating a distinct and independent mechanism of nNOS inhibition. To localize the calmodulin residues that account for impaired activation in the inhibitory CaM-cTnC chimeras, we conducted a detailed mutagenesis study, replacing CaM subdomains and individual amino acid residues with the corresponding residues from cTnC. This revealed that mutations in CaM helices 2 and 6 (its latch domain) have a disproportionate negative effect on nNOS activation. Thus, our evidence suggests that the CaM latch domain plays a critical role in its molecular switch function.
Complementary functioning of the component proteins of nitrogenase from several bacteria

The nitrogenase proteins from eight organisms have been highly purified, and a survey of their cross-reactions shows that the nitrogenase proteins from a wide variety of organisms can interact with one another. An active cross-reaction is the complementary functioning of the MoFe protein and the Fe protein from different organisms. Of 64 possible combinations of component proteins, 8 yielded homologous nitrogenases (components from the same organism); 45 of the 56 possible heterologous crosses generated active hybrid nitrogenases; 4 heterologous crosses yielded no measurable nitrogenase activity but did form inactive tight-binding complexes; 6 crosses did not give measurable activity; and 1 cross was not made. All these crosses were assayed for acetylene reduction, and some also were assayed for ammonia formation, hydrogen evolution, and ATP hydrolysis activity. The activity generated by combining two complementary heterologous nitrogenase components depended on pH, component ratio, and protein concentration, the same factors that determine the activity of homologous nitrogenases. However, several crosses showed an unusual dependency on component ratio and protein concentration, and some cross-reactions showed interesting ATP hydrolysis activity.
Reconciling facts with fiction: Minimum wages in a post-Keynesian perspective

There has long been a discussion about the employment impact of minimum wages and this discussion has recently been renewed with the introduction of an economy-wide, binding minimum wage in Germany in 2015. In traditional reasoning, based on the allocational approach of modern labour market economics, it has been suggested that the impact is clearly negative on the assumption of a competitive labour market and clearly positive on the assumption of a monopsonistic labour market. Unfortunately, both predictions conflict with the empirical findings, which do not show a clear-cut impact of significant size in any direction.
Learning curve in circular multipolar phased radiofrequency ablation of atrial fibrillation.

BACKGROUND Although atrial fibrillation (AF) ablation is considered a technically challenging procedure, studies on the learning curve of different pulmonary vein isolation (PVI) techniques are limited. We investigated the time-dependent changes in procedural parameters, complication rates, and in the 1-year clinical outcome during our initial experience with circular multipolar phased radiofrequency (RF) ablation. METHODS AND RESULTS The first 132 consecutive patients (40 female; age: 56.6 ± 10.4 years) who underwent PVI with phased RF ablation for paroxysmal or persistent AF at our center were included in the study. Procedural parameters and atrial arrhythmia-free survival were compared in the first, second and third group of 44 successive patients. All pulmonary veins were successfully isolated in 44 (100%), 41 (93.8%) and 42 (95.5%) patients in Tierce 1, 2 and 3, respectively (p = 0.233). The number of RF applications (per vein) required for isolation and fluoroscopy times demonstrated a significant decrease with experience, and a trend towards lower procedure times in Tierces 2 and 3 was also observed. Atrial arrhythmia-free survival rates at 12 months postablation were 68.18%, 75%, and 70.75% in Tierce 1, Tierce 2 and Tierce 3, respectively (p = 0.772). Pericardial tamponade requiring percutaneous subxiphoid drainage occurred in 1 patient (Tierce 3) as the only significant procedural complication. CONCLUSIONS A learning curve effect was demonstrated in fluoroscopy times and in the number of RF applications but not in the acute success and in the long-term arrhythmia-free survival with circular multipolar RF ablations.
Gene flow and mode of pollination in a dry-grassland species, Filipendula vulgaris (Rosaceae)

Filipendula vulgaris is a characteristic species of dry nonacidic grasslands in Denmark. This habitat type occurs only on marginal areas not suitable for agriculture or urbanization and that are by their nature fragmented. The population genetic structure of F. vulgaris was investigated in 17 populations within two regions of Denmark, using isozyme electrophoresis. Small populations were found to have significantly fewer polymorphic loci than larger populations, but all populations maintained the same common allelic variants. The degree of isolation of individual populations did not affect the amount of genetic variation. Offspring arrays revealed a very high outcrossing rate (0.96). The field study demonstrated a very high level of gene flow between populations considering that small insects are thought to be the main pollinators of this species. An experiment to verify whether pollen transport by wind could explain the results from the field study demonstrated long-distance transport from isolated plants to bagged plants. Filipendula vulgaris pollen grains are very small and this explains why outcrossed progeny were found using pollination bags with small pore sizes. We conclude that wind pollination is indeed possible and together with insect pollination is causing the observed patterns of genetic variation. The substantial gene flow between populations may be reducing the effects of genetic drift in the small fragmented populations of F. vulgaris.
On the Construction of Cross‐Sectional Statistical Standards for Growth

ABSTRACT. Cross‐sectional growth studies generally produce standardizing groups which are too small to permit the direct construction of standards. This problem can he circumvented by the introduction of appropriate structural assumptions. The two key papers in the literature which focus on this issue, Healy (1962) and Goldstein (1972), give methodologies which involve somewhat different premises. Healy takes the ages of individuals to he uniformly distributed over a well‐defined interval (hut their precise levels unknown). Goldstein by comparison supposes age levels to he known exactly. Both authors postulate that the characteristic of interest follows a Gaussian density whose mean and variance are each linear functions of time, a+bt and c+dt, say. In this paper we begin to explore the robustness of the two methods. Our results show that Healy's original moment solution to the estimation of (a, b, c and d) may be quite insensitive to departures from a uniform distribution for ages provided that this distribution remains symmetric about the interval mid‐point. Moreover, the distribution of the characteristic of interest may deviate from the Gaussian without too much effect, provided that symmetry about the mean a+bt is retained. However, there is much more doubt about asymmetric departures in both cases especially with regard to the estimation of b and d. Opting for simple‘interpolated’estimates of these two parameters (when possible) rather than Healy's original formula‐based versions will strongly aid robustness in general. Using some Icelandic cross‐sectional growth data referring to schoolchildren of age 7–10 years, we show that Goldstein's normality assumption can also have adverse effects if the actual distribution is somewhat skew. Transformation of the data to normality using the Box‐Cox power family is the route adopted here. A concomitant point well worth noting is that transformation to the Gaussian can he achieved using a constant variance target over surprisingly long time intervals.
The FMRFamide-like neuropeptide AF2 (Ascaris suum) is present in the free-living nematode, Panagrellus redivivus (Nematoda, Rhabditida)

Summary Available primary structural information suggests that the FMRFamide-related peptides (FaRPs) from parasitic and free-living nematodes are different, and that free-living forms may not represent appropriate models for the study of the neurochemistry of parasitic forms in the laboratory. However, here we report the isolation and unequivocal identification of AF2 (originally isolated from the parasite, Ascaris suum) from acidified alcoholic extracts of the free-living species, Panagrellus redivivus. While reverse-phase HPLC analysis of extracts revealed FMRFamide-immunoreactivity to be highly heterogeneous, AF2 was the predominant FMRFamide-immunoreactive peptide present (at least 26 pmol/g wet weight of worms). This peptide was also the major immunoreactant identified by an antiserum raised to the conserved C- terminal hexapeptide amide of mammalian pancreatic polypeptide (PP), which has been used previously to isolate neuropeptide F (NPF). These observations were confirmed by radioimmunoassay and chromatographic fractionation of an acidified alcoholic extract of A. suum heads. The FMRFamide-related peptides present in a nematode extract may be highly dependent on the extraction medium employed, and these data would suggest that this complement of neuropeptides may not be as different between parasitic and free-living nematodes as initial studies have suggested. Finally, all of the evidence suggests that NPF is not present in nematodes and that the PP-immunoreactant previously demonstrated immunochemically is probably AF2.
First report of the East African kdr mutation in an Anopheles gambiae mosquito in Côte d’Ivoire

Background. The intensive use of insecticides in public health and agriculture has led to the development of insecticide resistances in malaria vectors across sub-Saharan Africa countries in the last two decades. The kdr target site point mutation which is among the best characterised resistance mechanisms seems to be changing its distribution patterns on the African continent. The 1014F kdr mutation originally described only in West Africa is spreading to East Africa while the 1014S kdr mutation originally described in East Africa, is spreading to West and Central Africa. However, the East- kdr mutation has not been reported in Côte d'Ivoire so far. Methods. Immature stages of Anopheles gambiae s.l. were collected from breeding sites at the outskirts of Yamoussoukro, Côte d'Ivoire. Emerging 3–5 day old adult female mosquitoes were tested for susceptibility to deltamethrin 0.05%, malathion 5%, bendiocarb 1% and dichlorodiphenyltrichloroethane (DDT) 4% according to WHO standard procedures. A total of 50 An. gambiae s.l. specimens were drawn at random for DNA extraction and identification down to the species level. A subsample of 30 mosquitoes was tested for the East-African kdr mutation using a Taqman assay. Results. The tested mosquito population appeared to be strongly resistant to deltamethrin (1.03% mortality), bendiocarb (38.46% mortality) and DDT (0% mortality) with probable resistance observed for malathion (92.47%). Among the 41 mosquitoes that were successfully characterized, An. coluzzii was predominant (68.3%) followed by An. gambiae s.s. (19.5%) and a few hybrids (7.3%). Out of 30 specimens genotyped for East- kdr, a single hybrid mosquito appeared to be heterozygous for the mutation. Conclusion. The present study revealed the presence of the East- kdr mutation in Côte d’Ivoire for the first time in An. gambiae and highlights the urgent need to start monitoring the allele and genotype frequencies.
Complementary diagnosis of rotor asymmetries through the tracing of the Right Sideband Component in the stator startup current

In this paper, the tracing of the right sideband component (RSC) evolution in the stator startup current is proposed for the diagnosis of rotor asymmetries in induction machines. Although several works have dealt with the detection of the left sideband component (LSC) during the transient, few contributions have focused on the RSC, perhaps due to its more difficult detection, since it has often lower amplitude. In this work, several signal processing techniques, such as the short time Fourier transform (STFT), the discrete wavelet transform (DWT), the continuous wavelet transform (CWT) and band pass filtering are applied in order to extract this component during the transient. Several experimental startup current signals are used for this purpose. The results show that the transient extraction of the RSC might constitute an additional source of information which could enable a more reliable diagnosis of the fault, mainly in those cases in which the transient LSC evolution could be partially masked by other phenomena.
Linking Green Human Resource Management Practices to Environmental Performance in Hotel Industry

The hotel industry is growing rapidly in developing countries due to an increase in the tourism industry; however, on the other hand, the hotel industry is one of the sectors largely increasing the burden on the environment. Therefore, due to the massive number of environmental issues that hotel industry has encountered, there is an increasing force to pay a correct reaction to environmental issues and executing sustainable business practices such as the adoption of green human resource management (HRM) practices provide a win–win situation for the organization and its stakeholders. It, therefore, signals the need to examine how green HRM practices will enhance the environmental performance in the hotel industry. Grounded by resource-based view theory, this study utilized a research model examining the relationship between green HRM practices (green recruitment and selection, green training and development, green performance appraisal, and green compensation) and environmental performance in Malaysia’s hotel industry. Questionnaires were distributed to human resource (HR) managers/ executives in 3-, 4- and 5-star hotels in Malaysia. A total of 206 hotels participated in the study. The data collected were analysed using partial least squares structural equation modelling. Based on the analysis, the study revealed that green recruitment and selection, green training and development, and green compensation have a meaningful relationship with environmental performance, while green performance appraisal did not have a significant relationship with environmental performance. Our results extend previous research by not only highlighting the importance of green HRM practices in driving environmental performance but also indicating how each dimension of green HRM practices either enhances or inhibits environmental performance. This is the first empirical research that investigates the relationship between green HRM and environmental performance in the hotel industry literature.