Miracle-dz/UniFAR-FTUs huggingface dataset:
Changes in serum concentration of antioxidants following treadmill exercise testing in patients with suspected ischaemic heart disease

Twenty‐four subjects with suspected ischaemic heart disease underwent a treadmill exercise stress test (TEST). Nine individuals developed ischaemia as defined by standard criteria. Total plasma antioxidant status (TPAS), and serum concentrations of vitamin E were measured pre‐TEST, and 0, 1, 2, 4, 8 and 24 h following the treadmill test. Mean serum vitamin E concentrations fell by 33% in the group as a whole (from 9.53 ± 0.92 mg/L pre‐TEST to 6.39 ± 1.06 mg/L immediately post stress test, P < 0.02) and rose to baseline over the subsequent 24 h. The levels of serum vitamin E fell by 34% in the group of patients who had a positive TEST, and 32% in those who did not develop ischaemia during the TEST. Serum cholesterol concentrations also fell significantly during the TEST. In the total group serum cholesterol fell by 6.5% (P = 0.0052), and in the subgroup who were positive for ischaemia the fall in serum cholesterol was 10.3% (P = 0.004). The reduction in serum cholesterol was 4.1% in the subgroup who did not develop ischaemia (P > 0.05). Mean total plasma antioxidant status showed no significant temporal change for the group as a whole, although there was a nonsignificant decrease immediately post‐TEST in the ischaemic group and a slight rise at 8 h in the group negative for ischaemia.
Wheezing and Associated Risk Factors Among Children in Flood Prone Areas of a Central Nigerian Metropolis

Objectives: Our study investigated the prevalence of wheeze and its associated factors among children between the ages of 0 and 8 years in flood prone areas of Lafia local government area (LGA). Study Design: The study was a cross-sectional study. Materials and Methods: A total of 1,767 children resident in 300 households drawn from five council wards participated in the study. Questionnaires were used to obtain information relating to the children and their immediate environment. Relative humidity of each house was also measured. Wheezing in children was determined from interaction with their parents and confirmed through examination by trained health workers. Results and Discussion: Mean relative humidity of the wards ranged from 52.5%rh to 76.3%rh with 66.8% of children living in houses with relative humidity of >60%rh. Findings revealed a prevalence of 13.0% (n = 230) in the study area. Ages 3-8 years accounted for 70% wheeze cases while 0-2 years accounted for 30%. Age (AOR = 1.560; 95% CI = 1.023 – 2.378), mud houses (AOR = 1.812; 95% CI = 1.080 – 3.040), use of antibiotics (AOR = 143.593; 95% CI = 81.582 – 252.741) and local herbal concoctions (AOR = 114.530; 95% CI = 12.522 – 1047.494) were significantly associated with wheezing in children. Conclusion: The prevalence of wheeze in our study varied among children and was influenced by factors such as age, living in mud houses and recent or current use of antibiotics. This study advocates proper care and protection of children against factors that predispose them to wheezing.
ESTRATEGIAS MOTIVACIONALES EN INTERVENCIÓN CON AGRESORES DE PAREJA: EL PLAN MOTIVACIONAL INDIVIDUALIZADO / [MOTIVATIONAL STRATEGIES IN INTIMATE PARTNER VIOLENCE OFFENDER INTERVENTION: INDIVIDUALIZED MOTIVATIONAL PLANS]

Treatment adherence and motivation to change are among the main challenges to improve the effectiveness of batterer intervention programs (BIPs). The aim of this study was to examine whether adding a motivational strategy (i.e., Individualized Motivational Plan, IMP) increase the BIPs effectiveness, relative to the standard intervention alone. To this end, three studies were conducted with intimate partner violence offender samples, participating in a randomized clinical trial. Participants were randomly assigned to the control condition (standard BIP), or to the experimental condition (BIP+IMP). Final outcomes (i.e., official recidivism, physical and psychological violence, and recidivism • Correspondencia/correspondence: marisol.lila@uv.es Financiación/Funding: Este trabajo ha sido financiado por el Ministerio de Sanidad, Consumo y Bienestar Social (PND2018-021) y por la Universidad de Valencia (UV-INV_AE18-779244). PSICOLOGÍA JURÍDICA Y FORENSE: INVESTIGACIÓN PARA LA PRÁCTICA PROFESIONAL 290 risk) and proximal outcomes (i.e., treatment compliance -dropout and intervention dose, stage of change, emotion-decoding abilities, empathy and therapeutic alliance) were analysed. Participants in the experimental condition, at the end of the intervention, had lower levels of recidivism risk and self-reported physical violence, higher intervention dose, and were at higher stages of change at the end of the intervention program. They also were more accurate in decoding emotional facial signals and presented better cognitive empathy (i.e., perspective taking). Finally, participants in standard plus motivational condition established higher therapeutic alliance. Our results highlight the relevance of motivational strategies to increase the effectiveness in BIPs.
Interaction between Arginase and Ornithine Carbamoyltransferase

The inhibition of ornithine carbamoyltransferase by arginase in Saccharomyces cerevisiae, which is under the control of arginine and ornithine, involves a regulatory site on the ornithine carbamoyltransferase distinct from its catalytic site. This regulatory site is responsible for the partial inhibition of ornithine carbamoyltransferase by excess of ornithine. The strong inhibition of ornithine carbamoyltransferase by arginase in the presence of arginine requires the integrity of the mechanism which leads to partial inhibition by excess of ornithine. A new type of regulatory mechanism has been recently disclosed in Saccharomyces cerevisiae. This organism, as all species of the same genus, possesses an arginase which has the property to bind ornithine carbamoyltransferase, of these organisms. This binding produces the inhibition of ornithine carbamoyltransferase, leaving a normal arginase activity. The binding is under the control of arginine and ornithine. When arginine, at a concentration above ZOpM, and ornithine, above 3 mM, are simultaneously present, the association of the two enzymes can be shown by molecular sieving. This regulation, by reversible stoichiometric interaction between these enzymes belonging to opposite pathways, avoids the recycling of ornithine into arginine, when this amino acid is used as a source of nitrogen through its breakdown into ornithine, glutamate and ammonia [ 1,2]. The effectors are very specific : L-lysine, putrescine, L-a,y-diamino butyrate do not simulate rA-ornithine. D-Arginine, homoarginine, L-canavanine and L-argininic acid do not simulate arginine. Only agmatine acts as arginine. This raises the problem of the site of action of the two effectors which also are the substrates fo the two enzymes involved in this regulation. It was already shown that ornithine carbamoyltransferase alone is completely insensitive to arginine, but that its substrate, ornithine, when present above 7 mM, inhibits the catalytic activity. When arginase is added the inhibition by excess of ornithine is re
Résistance de Helicobacter pylori aux antibiotiques et d’autres substances antimicrobiennes. : Aspects moléculaires des mécanismes de détection

Contexte : Amelioration de la prise en charge de l’infection a H. pylori. Materiels et Methodes : Detection de H. pylori, la resistance a la clarithromycine, la tetracycline, la levofloxacine, et la determination des genes de pathogenicite ont ete realisees par PCR en temps reel, du gene de l’ARNr 23 S, de l’ARNr 16S, PCR classique et sequencage. L’evaluation de la stabilite du mutant resistant par rapport a l’isolat sensible etait obtenue par competition en culture sur cellules gastriques AGS sur une longue periode, suivie du sequencage du genome entier. L’evaluation de l’effet de l’extrait de Ceiba pentandra sur H. pylori etait realisee par la determination de la concentration minimale inhibitrice. Resultats : Prevalence de l’infection a H. pylori : 75.52%, resistance a la clarithromycine et tetracycline : 4,2% et 1,2%, resistance a la levofloxacine : 57%. Gene CagA : 92,2%. Gene Vac As1m1 : 82%. Absence de stabilite du mutant resistant dans le couple de souches 3695 R/S (ratio R / S 0,1), a 30 jours de la co-culture (p <0.05) ; ce mutant presentait la mutation A2142G, conferant la resistance a la clarithromycine. On notait la stabilite du mutant resistant dans l’autre couple de souches 3657R/S (ratio R / S ratio : 1,7) a 40 jours de la co-culture (p <0.05), avec developpement des mutations compensatoires ; ce mutant presentait la mutation A2143G. L’activite moderee a faible etait notee avec les extraits hydroethanolique et butanolique de Ceiba pentandra, avec une concentration minimale inhibitrice de 50 a 80 μg / ml.Conclusion : il est possible de traiter l’infection a H. pylori avec une therapie a base de clarithromycine au Congo. L’absence d’une activite forte ne permet pas de recommander Ceiba pentandra dans le traitement de l’infection a H. pylori . La reversion de la resistance dans le cas de H. pylori peut etre envisagee.
New phenotypes of Crossandra infundibuliformis var. danica through in vitro culture and induced mutations

In-vitro shoots of Crossandra infundibuliformis var. Danica were exposed to different doses of gamma rays and colchicines, respectively. Increasing dose of both mutagens caused reduction in mean shoot length at 2 months after treatments in the multiplication medium. Increasing dose of colchicine showed increase in the average number of shoots produced per culture. Shoot tip cultures treated with higher doses (>0.03%) of colchicine were abnormal due to stunted growth at 2 months after treatment in the same medium. At the same time, many leaf abnormalities such as changes in leaf size, shape, margin and apex were also observed in the treated shoots growing under in-vitro conditions. MS medium supplemented with 2mg/l IBA gave better results for in-vitro rooting in treated shoots. However, rootability of these mutants also decreased with increasing treatment dosage. The plants, which withstood both the mutagenic effect and the environmental adversities for three months under net house conditions, survived to flower. At flowering, among the treated population, a single individual from the 3 Krad gamma radiation treatment produced a solid mutant, named "Savindi", with altered leaf shape and flower colour. The plants maintained the new phenotypic characters even after five cycles of vegetative propagation indicating the potential to develop as a novel ornamental product.
Pressure Point Threshold and ME/CFS comorbidity as Indicators of Physiotherapy Response in Fibromyalgia

Current pharmacological treatments of Fibromyalgia (FM) are merely symptom palliative, as clinical trials have so far failed to provide overall benefits without associated harms. Polypharmacy often leads to patient´s health deterioration and chronic drug use to an eventual lack of patient´s response. Emerging evidence support that physiotherapy treatments based on mechanical triggers improve FM symptoms and therefore could be used for therapeutic purposes by themselves, or in combination with current pharmacological treatments, as part of integrative medicine programs. However, a paucity of studies rigorously and systematically evaluating this possibility exists. This study uses scores from validated standardized questionnaires, algometer pressure point threshold (PPT) readings and responses from a custom self-developed questionnaire to determine the impact of a pressure-controlled manual protocol on FM hyperalgesia/allodynia, fatigue and patient´s quality of life. The results show that patient´s baseline sensitivity to pain inversely correlates with treatment response in FM. Moreover, patients presenting comorbid ME/CFS do not seem to respond to the applied therapy as those presenting FM only. Thus, pre-treatment PPTs and ME/CFS comorbidity may serve as indicators to predict patient´s response to physiotherapy programs based on mechanical triggers, as the one evaluated here. These unexpected findings grant further explorations including the study of gene expression profiles associating to patient´s treatment response in the blood collection of samples generated by this study.
Environmental Diversity Assessment to Enhance Attractineness of Eco-tourism in Asir Region, Saudi Arabia

This is study follows environmental diversity assessment for geotourism development in Asir region. Geotourism seeks to supporting the tourism landscape in its interaction with the historical and archaeological, architectural or immaterial heritage, and requires diversification in terms of product, market and geographical potential. The study is based on various tourist facades and environmental diversity in Asir. As tourism development is a comprehensive undertaking involving many sectors, and these are the challenges to which the country’s tourism industry should respond to promote domestic tourism. quality and spatial pattern of tourism resources, climate comfort, and natural disaster possibility. Based on analyze multi-source datasets collected, geomorphological features of this area, we created a GIS database comprising geologic and topographic maps, and satellite images using these datasets. The findings of the study provided valuable insights into the role of environmental diversity in achieving tourism. The study examined the interrelationship between tourism and environmental diversity.
A conscious rethink: Why is brain tissue commonly preserved in the archaeological record? Commentary on: Petrone P, Pucci P, Niola M, et al. Heat-induced brain vitrification from the Vesuvius eruption in C.E. 79. N Engl J Med 2020;382:383-4. DOI: 10.1056/NEJMc1909867

ABSTRACT Brain tissue is ubiquitous in the archaeological record. Multiple, independent studies report the finding of black, resinous or shiny brain tissue, and Petrone et al. [2020 “Heat-induced Brain Vitrification from the Vesuvius Eruption in C.E. 79. ” N Engl J Med. 382: 383–384; doi:10.1056/NEJMc1909867] raise the intriguing prospect of a role for vitrification in the preservation of ancient biomolecules. However, Petrone et al. (2020) have not made their raw data available, and no detailed laboratory or analytical methodology is offered. Issues of contamination and misinterpretation hampered a decade of research in biomolecular archaeology, such that addressing these sources of bias and facilitating validation of specious findings has become both routine and of paramount importance in the discipline. We argue that the evidence they present does not support their conclusion of heat-induced vitrification of human brain tissue, and that future studies should share palaeoproteomic data in an open access repository to facilitate comparative analysis of the recovery of ancient proteins and patterns of their degradation. GRAPHICAL ABSTRACT
NOTE MORFO-BIOLOGICHE SU TETRASTICHUS ERIOPHYES TAYLOR PREDATORE DI ERIOFIDI DEL BOSSO

Del Tetrastichus eriophyes Taylor (Eym. Euloph. Tetrastichinae) vengono riportate la descrizione della larva matura e osservazioni di biologia condotte in massima parte in Campania, ad Ariano Irpino (Avellino), a 800 m s.m. Da queste, in sintesi, si deduce: l) - Alle tre specie di Acari Eriophyidae vittime di questo Tetrastichus finora conosciute (Aceria rudis Can., Cecidophyes ribis Nal. e Phytoptus avellanae Nal.) si aggiungono altre tre, delle quali due, I'Eriophyes buxi (Can.) e l'E. Canestrinii Nal. determinano ipertrofia delle gemme di bosso, ed una terza, l 'Aceria unguiculatus (Can.), e inquilina dell'E. buxi. Tutte queste specie hanno la caratteristica comune di svilup parsi in colonie composte da un enorme numero di individui su gemme che in seguito all'attivita del fitofago diventano abnormi, con elementi ipertrofici. Per il Tetrastichus eriophyes, quindi, e da ammettersi una specificita relativa alla famiglia Eriophyidae, ed una certa polifagia nell'ambito delle specie in essa comprese; pertanto non sono da escludersi futuri rinvenimenti del Calcidide su altri Eriofidi a comportamento analogo a quello delle vittime sopra ri cordate. 2) - Il T. eriophyes depone le uova nelle colonie di Acari e le sue larve vivono da predatrici; compie due generazioni all'anno (per l'Inghilterra, unico dato, se ne conosce una sola). Gli sfarfallamenti e successive ovideposizioni avvengono in primavera (principalmente in giugno) e in autunno (settembre e ottobre). Svernano le larve. 3)- Nel corso delle osservazioni le gemme del bosco sono risultate infestate dall'Eriofide per il 5-10%, con massimi del 20-30%; di que ste gemme il 30-40% ospitavano larve o pupe del Tetrastichus erio phyes. Brief morphological description of the full grown larva of Tetrastichus eriophyes Taylor (Hym. Eulophidae. Tetrastichinae) are here given. Biological data has been carried out in Avellino district (South Italy) during 1969, '70 and '71. On Buxus sempervirens L. > ( > ) are caused by trophical activity of Eriophyes buxi Can. and E. Canestrinii Nal. (Acar. Eriophyidae). In the > of E. buxi, another Eriophyide mite, Aceria unguiculatus (Can.), lives as guest. The larvae of T. eriophyes live between the hipertrofic leaves of > on Buxus sempervzrens L. (new datum). The adults emergs from the > mainly in June. The femals (the males are unknow) lay eggs whith a long ovipositor into the >: in each one of these one or two eggs are laid among the mites. The larva depends solely on the mites for its means of subsistence. The pupation occurs into the << galls » and the adults emerg in September-October (first generation). In this time the second generation, whith eggs laying, begins. The larvae of the second generation hibernate feeding on mites. On average, 30-40% of the << big-bud » contain the parasite (larvae or larvae and pupae) in my observation area all the time.
Captive breeding of the endangered San Esteban Chuckwalla, Sauromalus varius: Effects of a decade of captive breeding on maintaining genetic diversity

Abstract Increasingly, endangered vertebrate species are being maintained in captive breeding programs as a method of ensuring their survival. Despite these increasing numbers of captive breeding colonies, there have been few studies designed to examine the long-term success of these programs at maintaining genetic diversity. To elucidate the effectiveness of a captive breeding colony of the endangered species Sauromalus varius (the San Esteban Chuckwalla) at maintaining genetic variation over time, we employed seven polymorphic microsatellite loci. F-statistics and analysis of molecular variance strongly suggest that the colony is exhibiting genetic signs of inbreeding. Genetic variation within the colony has decreased by an average of 12.2% within the colony between the 2 y sampled with an average loss of 30.5% of genetic variation within offspring. This study provides an important test of the effectiveness of captive breeding colonies at maintaining genetic variation within a vertebrate group over time.
PEEK material in dentistry

Polyetheretherketone (PEEK) material is a polycyclic, aromatic, thermoplastic polymer that is semi-crystalline and has a linear structure. PEEK has good mechanical and electrical properties such as resistance to high temperature and resistance to hydrolysis. In addition, because of the property of high biocompatibility, use of PEEK has increased in orthopedic and trauma cases. The most characteristic property of PEEK material is that it has a low elasticity modulus, close to that of bone. It has been suggested that stress-based problems could be reduced with this material due to the low elasticity modulus. In the light of this information, PEEK material could be considered as an alternative to conventional materials in the field of dentistry.
Investigating an agent based modelling approach for SDI planning: A case study of Tanzania NSDI development

Spatial Data Infrastructure (SDI) provides a platform for spatial data sharing and is a key for sustainable development. Developing countries, including Tanzania, are at different stages of implementing SDIs. The importance and advantage of implementation lie in the fact that considerable funds can be saved by avoiding duplication of data, and improving quality of decisions making as well as public services. However, SDI is very complex in nature, including many influencing factors and different stakeholders. This paper investigates the possibilities of using Agent-Based Modelling (ABM) for simulating an SDI development process in Tanzania, for better understanding and making better planning. The roles and actions of organizations were identified through interviews, and the results were analysed. The behaviour of individual organizations (stakeholders) while interacting with the system were observed and analysed. The growth results in terms of data availability, standards, and data sharing for each organization were plotted and priority tables were generated. The model was evaluated for consistency and the results were judged to be within a reasonable range. The ABM simulation depicted the main attributes of agents, their roles and their interactions while pursuing SDI development in Tanzania. The results will help SDI planners and stakeholders to understand the roles of partners and prioritize activities and actions for successful SDI implementation.
Landmark Detection Using Squeeze and Excitation Residual Neural Networks

Landmark Recognition is the technology that can anticipate landmark names straightforwardly from picture pixels, to help individuals better comprehend and sort out their photograph accumulations and for law enforcement officials to gauge the location of images submitted as evidence. Image classifications techniques have shown remarkable improvements over the last few years. To further improve computer vision technologies and methodologies, researchers are now concentrating on highly specific types of classification. Instead of classifying cats, cars or buildings, researchers are trying to classify among different types of landmarks - both natural and man-made. In the present age, a tremendous roadblock in landmark recognition research is the lack of large, well labelled datasets. To rectify this, Google has come up with the Google Landmark Recognition Dataset. The dataset contains 1.2 million images of 15000 categories of landmarks. For the project, a subset of Google Landmark Recognition dataset has been used. Various latest classification algorithms, like AlexNet, ResNet, SE-ResNet, VGG-16 and Inception v3 have been implemented to classify the images. Among them, the SE-ResNet architecture achieves the lowest loss value of 0.1822 and accuracy of 94.08% on the training set.