Miracle-dz/UniFAR-FTUs huggingface dataset:
Maternal infanticide associated with mental illness: prevention and the promise of saved lives.

OBJECTIVE Although maternal infanticide is a rare event, a high proportion of cases occurs in the context of postpartum mental illness. The author reviews historical, legislative, and contemporary psychiatric perspectives on infanticide and discusses ways in which the psychiatric community can improve prevention of infanticide and promote appropriate treatment of mentally ill women who commit infanticide. METHOD The case of Texas v. Andrea Yates, involving a mother with mental illness who drowned her five children, is used to illustrate society's complicated reactions to infanticide in the context of postpartum mental illness. RESULTS In the United States, the complexity of the response to infanticide is demonstrated by the judicial system's reaction to such cases. Whereas England's Infanticide Law provides probation and mandates psychiatric treatment for mothers with mental illness who commit infanticide, "killer mothers" may face the death penalty in the United States. Contemporary neuroscientific findings support the position that a woman with postpartum psychosis who commits infanticide needs treatment rather than punishment and that appropriate treatment will deter her from killing again. Psychiatrists have a vital role in recognizing the signs and symptoms of peripartum psychiatric disorders, particularly postpartum psychosis, and in early identification of and intervention with at-risk mothers. CONCLUSIONS The absence of formal DSM-IV diagnostic criteria for postpartum psychiatric disorders promotes disparate treatment under the law. The psychiatric community should develop guidelines for the treatment of postpartum disorders, foster sharing of knowledge between psychiatry and the law, and do more to enlighten society about the effects of mental illness on thought and behavior so that decisions about the treatment and punishment of mentally ill persons will not be left exclusively in the hands of the judicial system.
Paretic Upper-Limb Strength Best Explains Arm Activity in People With Stroke

Background and Purpose The purpose of this study was to determine the relationship among variables of upper-limb impairment, upper-limb performance in activities of daily living (activity), and engagement in life events and roles (participation) in people with chronic stroke. Subjects The subjects were 93 community-dwelling individuals with stroke (≥1 year). Methods This study, which was conducted in a tertiary rehabilitation center, used a cross-sectional design. The main measures of impairment were the Modified Ashworth Scale, handheld dynamometry, sensory testing (monofilaments), and the Brief Pain Inventory. The main measures of activity were the Chedoke Arm and Hand Activity Inventory (CAHAI) and the Motor Activity Log (MAL). The main measure of participation was the Reintegration to Normal Living (RNL) Index. Results Paretic upper-limb strength (force-generating capacity) (r=.89, P<.01), grip strength (r=.69, P<.01), and tone (resistance to passive movement) (r=−.80, P<.01) were the impairment variables that were most strongly related to activity. Tone (r=−.23, P<.05) and CAHAI scores (r=.22, P<.05) had a significant, but weak, relationship to participation. Upper-limb strength accounted for 87% of the variance of the CAHAI scores and 78% of the variance of the MAL scores. In the participation models, tone and CAHAI scores accounted for 5% of the variance of the RNL Index scores. Discussion and Conclusion Paretic upper-limb strength had the strongest relationship with variables of activity and best explained upper-limb performance in activities of daily living. Grip strength, tone, and sensation also were factors of upper-limb performance in activities of daily living. Increased tone and upper-limb performance in activities of daily living had a weak relationship with participation.
Loss of Time Delay Signature in Broadband Cascade-Coupled Semiconductor Lasers

Numerical and experimental investigations of time delay concealment and chaos bandwidth enhancement in three semiconductor lasers with a cascade scheme are presented. The cascade system is composed of an external-cavity master laser, a solitary intermediate laser, and a solitary slave laser. The results show that the first two lasers are used for concealing time delay signature, and the last two lasers are used for bandwidth enhancement. For large parameter regions of injection strength and frequency detuning, time delay concealment and bandwidth enhancement of chaotic signals are simultaneously achieved by adopting the simple cascade configuration.
A Variational Method for Second Order Shape Derivatives

We consider shape functionals obtained as minima on Sobolev spaces of classical integrals having smooth and convex densities, under mixed Dirichlet--Neumann boundary conditions. We propose a new approach for the computation of the second order shape derivative of such functionals, yielding a general existence and representation theorem. In particular, we consider the $p$-torsional rigidity functional for $p \geq 2$.
Tunable slot antenna using varactors and photodiodes

In this work, a single slot antenna fed with a microstrip line was tuned over a wide band of frequencies in two ways using a varactor and a photodetector. Both configurations were compared in terms of their frequency agility and bandwidth. These techniques maintain a simple, compact, and low cost antenna structure.
Pregnancy Outcomes at the Indiana Women’s Prison

This article presents birth weight outcome data for 200 pregnancies at the Indiana Women’s Prison (IWP) over the last 4 years. Overall, 5.5% of the pregnancies at IWP had low birth weight outcomes. The rate was only 2% for women who were incarcerated for more than 4 weeks and got prenatal care. These outcomes were better than the published outcomes for pregnancies in the State of Indiana.
Association of the apolipoprotein A‐IV: 360 gln/his polymorphism with cerebrovascular disease, obesity, and depression in a Brazilian elderly population

The identification of genetic polymorphisms as risk factors for complex diseases can be relevant for their prevention, diagnosis, and prognosis. The apolipoprotein A‐IV: 360 Gln/His polymorphism was investigated in 383 elderly individuals, who were participants of a longitudinal study commenced in 1991. The major morbidities that affect elderly people, such as cardiovascular diseases, diabetes, low cognitive function, depression, and obesity, were extensively investigated. DNA was isolated from blood cells, amplified by PCR, and digested with Fnu4HI. In this population the frequency of the His allele was 0.056 and the genotypes were distributed according to Hardy–Weinberg equilibrium. Logistic regression analysis showed a significant association between the presence of His allele and cerebrovascular disease and/or transitory ischemic attack (odds ratio) (OR = 3.070, P = 0.027), obesity (OR = 2.241, P = 0.047), and depression (OR = 2.879, P = 0.005). This study indicates that the presence of the rare allele in elderly people can play a significant role in the occurrence of multifactorial diseases. This is the first study analyzing this polymorphism in elderly people in Brazil. More studies should be encouraged to elucidate the mechanisms involved in these diseases. © 2005 Wiley‐Liss, Inc.
Capturing diagnosis-timing in ICD-coded hospital data: recommendations from the WHO ICD-11 topic advisory group on quality and safety.

PURPOSE To develop a consensus opinion regarding capturing diagnosis-timing in coded hospital data. METHODS As part of the World Health Organization International Classification of Diseases-11th Revision initiative, the Quality and Safety Topic Advisory Group is charged with enhancing the capture of quality and patient safety information in morbidity data sets. One such feature is a diagnosis-timing flag. The Group has undertaken a narrative literature review, scanned national experiences focusing on countries currently using timing flags, and held a series of meetings to derive formal recommendations regarding diagnosis-timing reporting. RESULTS The completeness of diagnosis-timing reporting continues to improve with experience and use; studies indicate that it enhances risk-adjustment and may have a substantial impact on hospital performance estimates, especially for conditions/procedures that involve acutely ill patients. However, studies suggest that its reliability varies, is better for surgical than medical patients (kappa in hip fracture patients of 0.7-1.0 versus kappa in pneumonia of 0.2-0.6) and is dependent on coder training and setting. It may allow simpler and more precise specification of quality indicators. CONCLUSIONS As the evidence indicates that a diagnosis-timing flag improves the ability of routinely collected, coded hospital data to support outcomes research and the development of quality and safety indicators, the Group recommends that a classification of 'arising after admission' (yes/no), with permitted designations of 'unknown or clinically undetermined', will facilitate coding while providing flexibility when there is uncertainty. Clear coding standards and guidelines with ongoing coder education will be necessary to ensure reliability of the diagnosis-timing flag.
Towards interactive pen input of visual languages

Describes work in progress towards development of integrated pen-based software systems for processing visual languages (VL). The primary assumption is that graphical input, editing and VL parsing facilities can be treated as system resources to be shared among many applications. Prototypes of a pen-stroke editor, VL parser, and VL-based application are described. <<ETX>>
Propagation d'ondes dans un guide inhomogène : application à la cochlée

Dans la cochlee, la reponse couplee de sa structure et de son fluide interne peut etre representee sous la forme d’une onde dont les caracteristiques varient en fonction de la position longitudinale. La methode asymptotique Wentzel-Kramers-Brillouin est adaptee a la modelisation de ce type d’onde. Dans un premier temps, cette methode est reprise. Un modele numerique est egalement developpe et les resultats des deux methodes sont compares. Dans un deuxieme temps, la metohde Wentzel-Kramers-Brillouin est amelioree afin de prendre en compte le couplage entre plusieurs ondes. Le couplage d’un mode propagatif avec des modes evanescents est realise et valide. Dans la cochlee, la stimulation des cellules cillees resulte d’un mouvement de cisaillement de la membrane tectoriale et de flexion de la membrane basilaire. Le couplage entre ces deux modes de deformation est encore peu connu et offre une perspective interessante. Dans un troisieme temps, une nouvelle methode couplant la methode Wentzel-Kramesr Brillouin et une methode numerique est developpee et validee afin de determiner des modes transverses de propagation. Cette methode est appliquee a la mecanique cochleaire et un mode de flexion de la membrane basilaire et un mode relatif a un mouvement de cisaillement de la membrane tectoriale sont determines. Enfin, une experience inspiree des cochlees artificielles est concue et realisee. La propagation d’ondes est observee et la tonotopie est mesuree et comparee aux modeles. Afin de limiter la reflexion des ondes et de faciliter la mesure, une combinaison originale du trou noir acoustique avec une lame de largeur variable est utilisee.
Zillow Talk: The New Rules of Real Estate

| #129 in Books | 2015-01-27 | 2015-01-27 | Original language: English | PDF# 1 | 9.38 x 1.00 x 6.38l, . 0 | File type:PDF | 288 pages The many reviews about Zillow Talk: The New Rules of RealEstate | By Spencer Rascoff, Stan Humphries beforepurchasing it in order to gage whether or not it would be worth mytime, and all praised Zillow Talk: The New Rules ofReal Estate, declaring it one of the best , something that allreaders will enjoy.
Detection of Helicobacter pylori in sewage and water using a new quantitative PCR method with SYBR® green

Aims: To demonstrate the application of a new quantitative polymerase chain reaction (qPCR) technique for the determination of Helicobacter pylori concentrations in water, and to use this method to investigate the occurrence of the bacteria in sewage. The other aim was to study the survival capacity and detectability of the bacteria in artificially contaminated groundwater at different temperatures of 4 and 15°C.
REVIEW ARTICLE: Neurotransmitters regulate cell migration in the telencephalon

The complex cytoarchitectonic organization of the adult mammalian telencephalon reflects the elaborate patterns of cell migration that contribute to its generation. The migration by neurons in the CNS can broadly be divided into two categories: radial and tangential. Experimental observations in the telencephalon have shown that glutamatergic projection neurons are born in the progenitor compartment of the dorsal telencephalon and migrate radially to integrate the cortical plate, whereas most γ‐aminobutyric acid (GABA)ergic interneurons are generated in the ganglionic eminences and navigate through multiple tangential paths to settle into distinct telencephalic structures. Despite progress towards the understanding of the genetic determinants that specify the fate of neuronal progenitors, much remains unknown about the mechanisms that direct their migration into specific regions of the telencephalon. Interestingly, besides their function in synaptic transmission, neurotransmitters have been shown to promote several developmental processes that contribute to the establishment and maintenance of the CNS. In this respect, recent studies have highlighted a role for neurotransmitters through activation of their receptors in regulating cell migration in the telencephalon. This review summarizes and discusses the growing body of literature implicating neurotransmitters and their cognate receptors as part of a complex molecular machinery that regulate the migration of immature neurons in the telencephalon during development and in adulthood.
Une approche systémique à base d'agents et de graphes dynamiques pour modéliser l'interface logistique port-métropole. (A Systemic Approach with an Agent-Based Model and Dynamic Graphs to Model the Urban-Port Interface)

Un systeme logistique est une composante essentielle d'un systeme spatial dans lequel les acteurs s'organisent autour d'infrastructures pour faire circuler des flux (de marchandises, d'information et financier) sur un territoire. L'organisation logistique globale resulte d'un processus auto-organise et distribue de la part des acteurs. Ce travail vise a comprendre, a de multiples echelles, comment des acteurs autonomes et tres heterogenes (dans leurs modes de fonctionnements et dans leurs objectifs), s'organisent collectivement autour des infrastructures a leurs dispositions pour gerer des flux soumis a un ensemble de contraintes (temporelles, spatiales,.). On propose ici un modele oriente agent permettant de simuler les processus de creation et d'organisation des flux lies a la logistique sur un territoire. Le modele prevoit de decrire l'interface entre les flux internationaux et les flux urbains afin de comprendre comment les dynamiques portuaires et urbaines cohabitent au sein du systeme. Le modele integre une dynamique structurelle et organisationnelle grâce aux graphes dynamiques afin de representer l'evolution du systeme. Le modele permet ainsi aux agents de s'adapter, comme dans la realite, a des perturbations du systeme.
Combination of Box-Jenkins and MLP/RNA models for forecasting

This study aims to predict the values of the time series of UHT milk demand in a dairy industry by combining forecasting of ARIMA and MLP/RNA models and compare the results to the individual models, exemplifying the combined forecast for the production planning. Eight predictions combining techniques were used and, after the use of statistical techniques, the results obtained by fitting the ARIMA and MLP/RNA templates were compared with the results obtained in the proposed combinations. The results showed that the combination of SARIMA models (3,0,1)(1,1,0)12 and DMLP the inverse mean square method provided a performance in the forecast, for six months ahead, 66.5% higher than the individual models where the combination of forecasts provided a RMSE of 1.43 and MAPE of 2.16. The forecast for 12 months on, the performance of the combination was 56.5% higher compared to individual models, with RMSE of 2.86 and MAPE of 3.70%. In both cases, the combination of predictions showed superior results.
Neonatal Epilepsy Syndromes and Generalized Epilepsy with Febrile Seizures Plus (GEFS+)

∗†‡Ingrid E. Scheffer, §Louise A. Harkin, §Leanne M. Dibbens, §‖John C. Mulley, and ∗Samuel F. Berkovic ∗Department of Medicine (Neurology), The University of Melbourne, Austin Health, Melbourne, Victoria; †Department of Neurology, Royal Children’s Hospital, Melbourne, Victoria; ‡Department of Neurosciences, Monash Medical Centre, Melbourne, Victoria; §Department of Genetic Medicine, Women’s and Children’s Hospital, Adelaide, South Australia and Department of Pediatrics, The University of Adelaide, Adelaide, South Australia; and ‖School of Molecular and Biomedical Sciences, The University of Adelaide, Adelaide, South Australia, Australia
Fault Tolerant Control design for polytopic uncertain LPV systems: Application to a quadrotor

This paper presents a Fault Tolerant Control (FTC) design for polytopic uncertain Linear Parameter-Varying (LPV) systems, applied to an aerospace application: a quadrotor. Depending on the information available about the fault, the FTC strategy could be passive FTC, active FTC without controller reconfiguration or active FTC with controller reconfiguration. The FTC strategy is designed taking into account the robust LPV polytopic framework. The effectiveness of the proposed method is demonstrated by its application to a quadrotor.
A Knowledge-Based Perspective on Contract Choice in Application Outsourcing

A key governance decision in application outsourcing projects is the choice between fixed-price and time-and-materials contracts. While existing research draws on economic theories to explain contract choice, knowledge-based perspectives on contract choice remain underdeveloped. In this paper, we formulate and empirically test such a knowledge-based perspective. We argue that different contract types (fixed-price versus time-and-materials) assign the primary responsibility for coordination to different parties (vendor versus client) and that the ability of each party to coordinate the work depends on task characteristics. Specifically, vendors are most able to coordinate work when knowledge specificity is low and when task scope is high. Data on 1035 contract choices at 223 clients support these ideas. Fixed-price contracts are more frequent under low knowledge specificity and under high task scope. Our key contribution lies in formulating and empirically substantiating a knowledge-based perspective on contract choice.
Identification of Genes Required for Embryo Development in Arabidopsis1[w]

A long-term goal of Arabidopsis research is to define the minimal gene set needed to produce a viable plant with a normal phenotype under diverse conditions. This will require both forward and reverse genetics along with novel strategies to characterize multigene families and redundant biochemical pathways. Here we describe an initial dataset of 250 EMB genes required for normal embryo development in Arabidopsis. This represents the first large-scale dataset of essential genes in a flowering plant. When compared with 550 genes with other knockout phenotypes, EMB genes are enriched for basal cellular functions, deficient in transcription factors and signaling components, have fewer paralogs, and are more likely to have counterparts among essential genes of yeast (Saccharomyces cerevisiae) and worm (Caenorhabditis elegans). EMB genes also represent a valuable source of plant-specific proteins with unknown functions required for growth and development. Analyzing such unknowns is a central objective of genomics efforts worldwide. We focus here on 34 confirmed EMB genes with unknown functions, demonstrate that expression of these genes is not embryo-specific, validate a strategy for identifying interacting proteins through complementation with epitope-tagged proteins, and discuss the value of EMB genes in identifying novel proteins associated with important plant processes. Based on sequence comparison with essential genes in other model eukaryotes, we identify 244 candidate EMB genes without paralogs that represent promising targets for reverse genetics. These candidates should facilitate the recovery of additional genes required for seed development.
NSE as a biomarker of mercury exposure

In their impressive and timely study, Yilmaz et al. (2014) found that circulating biomarkers – neuron-specifi c enolase (NSE), glutamate receptor (GRIA 1) and S100B were associated – at least in part – with overexposure to metallic mercury vapor (Hg 0 ) among children and adolescent. 1 We welcome and support the article by Yilmaz et al. (2014) but we would like to raise one point. 1 In the Materials and Methods section, they state that “ The children who have a blood mercury level higher than 10 micrograms per liter had a chelation therapy with dimercaptosuccinic acid ” . 1 Therefore, some patients in the study received doses of water-soluble sodium salt of 2,3-dimercapto-1-propane sulfonic acid (DMPS) to diminish the density of blood mercury concentrations. 1 Generally speaking, chelating agents – as DMPS – are medications that have been shown to reduce heavy metals in case of metals overexposure in humans. 2 Given that we have previously noted a potential association between serum NSE levels and whole-blood levels of mercury related to the toxic effects induced by mercury vapors (Hg 0 ), 3 it would have been valuable to consider the use of chelation therapy as potential confounding variable. If so, mercury biomarker levels NSE associated with mercury overexposure would have been higher than they reported in their outcome. 1 This is a possible explanation of the little correlation that they found between the clinical use of serum NSE and recent exposure to mercury vapor. 1
The impact of new technologies on the labour market and the social economy

This study investigates the relationship between innovation, new technologies, employment and inequality. Today, there is an intense discussion on these topics, in particular on the employment effects of new information and communication technologies. Based on the existing literature and experience from previous technological revolutions, the study strikes an optimistic note about the future. It argues that innovation is labour-friendly: it destroys, but also creates employment. In previous times, the race between job creation through product innovation and job destruction through process innovation has been won by the job-creating effects of innovation. As a result, the author does not expect that digitalisation will lead to mass unemployment. However, in his view, the costs of digitalisation are unevenly distributed due to the skill-biased nature of technological change. Low-skilled workers, who face a higher risk of job displacement, are therefore particularly likely to bear much larger costs than others. Another group at risk are those whose occupations involve a high share of routine tasks, which is particularly the case in the service industries. The study concludes that the challenge of the future lies in coping with rising inequality as a result of technological change.