Miracle-dz/UniFAR-FTUs huggingface dataset:
Knowledge extraction on international markets from patent bases: a study on green patents

Goal: This article aims to propose a model for stratifying technological information from meta-data contained in international patent bases, capable of supporting the strategic decision making that potentiates actions directed to foreign trade. Design / Methodology / Approach: This applied research was based on the KDD Knowledge Discovery in Databases methodology and carried out a study focused on green patents. Patent bibliographic data published in the Patent Cooperation Treaty (PCT) from 2003 to 2012, focusing on alternative energies, more precisely on biofuels, were obtained from the Derwent database, with the search string based on the Green Patents IPC Inventory, published by the World Intellectual Property Organization (WIPO). After treatment and sanitization, more than 36,000 resulting records were performed under C4.5 algorithm, denominated J-48 from the software Weka, resulting in Brazil as the destination country. Results: A decision tree was established, in which Mexico was highlighted as the main discretionary country. It was also verified the adhesion of the other emerging countries, which, along with Brazil, compose the BRICS. Limitations of the investigation: The proposed model is limited to areas that show intensive use of technology in products and processes. Practical implications: It could be inferred that the proposed method can help companies to identify international markets more sensitive to a certain technology, from a free database, reliable and capable of being used by micro and small companies. Originality / Value: In scientific communication, it is not easy to find Data mining applied to Patent database, and in this study, BRICS cluster were identified in Green patents WIPO deposit.
" Smoke on the water" - Wasserpfeifenkonsum bei Jugendlichen in Deutschland (Ergebnisse aus KiGGS Welle 1) " Smoke on the water" - waterpipe tobacco smoking among adolescents in Germany (Results of KiGGS Wave 1)

In Germany, as in other countries, waterpipe (shisha) tobacco smoking has been increasing in popularity. While in the last 15 years overall smoking prevalence, particularly cigarette smoking, has declined among adolescents, waterpipe smoking has become an emerging type of tobacco use. According to the results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS Wave 1, 2009–2012), lifetime prevalence of waterpipe use among 12- to 17-year-olds was 28.9 per cent. Approx imately one-? fth (20.6 %) of the adolescents reported waterpipe use in the past 12 months, onetenth (10.0 %) reported current use (at least once during the past 30 days). In both sexes, prevalence increased with age. Waterpipe smoking rates were signi? cantly higher among boys than girls. Among boys with a two-sided migration background (both parents, or the child and one parent, immigrated to Germany) waterpipe use was more common compared to non-immigrants. Due to waterpipe related health and addiction risks that are often underestimated by adolescents, speci? c health education and prevention measures are necessary.
Hubungan antara Serotipe Dengue dengan Manifestasi Klinis Ruam pada Pasien Dbd di RSUD Wonosari YOGYAKARTA Tahun 2015

Clinical manifestations of dengue are different in each patient, not everyone infected with dengue virus will show the manifestation of severe dengue, many dengue cases without any clinical manifestations in the form of a rash. The purpose of the study is to examine the relationship between dengue serotypes with clinical manifestations of rash in patients with DHF in Yogyakarta Wonosari Hospital in 2015. This study was an analytical study, using cross sectional approach. The population in this study were all patients of dengue in hospitals Wonosari Yogyakarta in 2015 with a total of 190 people which 38 samples were taken from. Data analysis used was chi square test with 95% significance level. The results showed that the largest percentage is in DENV serotypes 3 (50.0%), showing no clinical manifestations of rash (84.2%), the age categories of children 5-14 years old (34.2%), female gender (52.6%) and duration of heat for 5 days (47.4%). Chi square test results showed no significant correlation between dengue serotypes (p value = 0.188, 95% p value> 0.05), age (p value of 0.779, 95% p value> 0.05), gender (p value 0.663, 95% p value> 0.05), and duration of heat (p value = 0.319, 95% p value> 0.05) with clinical manifestations of rash. The variables studied showed that dengue serotypes variables, age, gender, and duration of heat do not affect the onset of clinical manifestations of rash. It is necessary to expand the sentinel surveillance area so that the spread of dengue serotypes in Indonesia actually mapped clearly.
Heart rate variability in chronic obstructive pulmonary disease and its correlation with disease severity in South Indian population

Background: Cardiovascular diseases associated with chronic obstructive pulmonary disease (COPD) account for 50% of COPD deaths. Autonomic dysfunction and poor pulmonary function increase the cardiovascular risk in COPD patients. Severity of COPD can be assessed by forced expiratory volume in 1 s. Autonomic balance can be assessed by heart rate variability (HRV). There are variations in the reports of COPD patients regarding the level or onset of dysfunction is a sympathetic or parasympathetic system in them. Aims and Objectives: In our study, we intended to assess HRV parameters such as, total power (TP), high frequency normalized units (HFnu), low frequency normalized units (LFnu), LF/HF ratio, mean HR, root mean square of the successive differences (RMSSD), NN50, and pNN50 among different stages of COPD and also to identify the association of these HRV parameters with disease severity. Materials and Methods: It is a cross-sectional study done on (n = 130) male stable COPD patients. Anthropometric parameters, HRV parameters, and pulmonary function test were assessed. Later, based on the Global Initiative for Chronic Obstructive Lung Disease stage criteria (mild, moderate, severe, and very severe), they were divided into four subgroups. Data were analyzed by SPSS 19.0 version software. KruskalWallis test was used to find a statistical difference between the groups. Correlations between the variables were done using Spearman correlation test. Results: LF/HF ratio (2 ± 0.5) was increased when compared to reference value reported by the previous studies. TP, HFnu, and RMSSD levels were significantly decreased in very severe, severe, and moderate COPD patients when compared to mild COPD patients. The mean HR, LFnu, and LF/HF ratio levels were significantly increased in very severe, severe, and moderate COPD patients when compared to mild COPD patients. TP, HFnu, and RMSSD levels negatively correlated with disease severity and mean HR, LFnu, and LF/HF ratio positively correlated with disease severity. Conclusion: We have noted that cardiac autonomic dysfunction in the form of increased sympathetic and reduced parasympathetic activity occurs in COPD patients and the association was more prominent when the disease severity increased.
Herb-drug interactions via modulations of cytochrome P450 enzymes

Nowadays, whereas herbal supplements are being increasingly popular worldwide, the incidence of herb-drug interactions are being reported spontaneously. One main mechanism causing herb-drug interactions is potential of an herb to modulate capacity or ability of drug-metabolizing enzymes, specifically cytochrome P450 (CYP450), a major superfamily of enzymes responsible for biotransformation in order to excrete xenobiotic out of the body. Herewith, cases of famous herbs, e.g., St. John’s wort, grapefruit, Ginkgo biloba , black pepper, and pomegranate, and their potentials in modulating CYP450 activities are being reviewed. St. John’s wort is a potent inducer of CYP3A4, CYP2E1, and CYP2C19 while, at the same time, being popularly used as a combination therapy in patients with depression. Grapefruit juice, extensively consumed due to its taste, nutritive value, and biological benefits, is a potent CYP3A4 inhibitor. G. biloba , one of the most consumed ethnomedicines especially in senior people and patients suffering from dementia, has been reported to inhibit CYP3A4. Black pepper, well known for its pungent taste and extensively used in numerous dishes, is a potent CYP3A4 inhibitor, and therefore, is known and used as a bioenhacer. Pomegranate, a fruit popularly consumed global due to its delicious taste and biological benefits, is reported to inhibit CYP3A4 similarly to grapefruit juice. Both practitioners and patients should be interested and concerned on information of herb-drug interaction, as ignorance can cause life-related consequences. Patients should acknowledge the impact of the self- co-administered therapies while practitioners should consider these supplements, either intentionally or unintentionally, which may convey potential effects on the therapeutic outcome or adverse toxicity.
Reliability and validity of the Iranian version of the human immunodeficiency virus specific World Health Organization quality of life BREF questionnaire

B a c k g r o u n d & Aim: Quality-of-life (QOL) among human immunodeficiency virus (HIV)-infected people has been the center of focus worldwide. The World Health Organization QOL Group (WHOQOL Group) has developed a 31-item QOL questionnaire, which has been translated and used in many countries. This paper aimed at examining the reliability and validity of Persian version of HIV specific WHOQOL scaleBREF questionnaire (WHOQOL-HIV BREF) in Iranian patients suffering from HIV/acquired immunodeficiency syndrome (AIDS). Methods & Materials: For the purpose of this cross-sectional study, a standard “ forward- backward” translation and cognitive debriefing were initially applied. Subsequently, 150 people living with HIV/AIDS visitingTertiary Referral Consultation Center for clients with risky behaviors in Tehran completed the Persian version of the questionnaire. Validity was assessed using Known Group Comparison through ANOVA test. Internal reliability was measured by Cronbach 's alpha and Split-Half coefficients. R e s u lt s : WHOQOL-HIV BREF was capable to discriminate between two groups who were different in their QOL (P< 0.05). Internal consistency analysis was satisfactory for domains (Cronbach’s alpha =0.64- 0.85), and whole the instrument (Cronbach's alpha=0.93). C on c l u sio n : The Persian version of WHOQOL-HIV BREF is a reliable and valid instrument to assess the QOL among Iranian HIV-infected population.
Comparative analysis of effectiveness parameters of laparoscopic and open appendectomy in children

Introduction: Acute appendicitis is one of the most common indications for urgent surgical intervention in children. An open appendectomy has been applying since the end of the XIX century, but for the last thirty years, laparoscopic appendectomy became an alternative. There is no consensus among surgeons, which method is suitable for pediatric patients. Aim: The aim of the research is to establish which of these two methods has therapeutic advantages in children, analyzing comparatively their operative and postoperative course in the treatment of acute appendicitis. Material and methods: The study includes 330 children with acute appendicitis. Patients were divided into 2 groups: operated by the method of open appendectomy (OA) and laparoscopic surgery (LA). Analyzed parameters were: methods of operation, age and sex of patients, intraoperative findings, duration of surgery, length of hospital stay, intraoperative and postoperative complications, preoperative levels of leukocytes, duration of antibiotic therapy and pain therapy. Results: In total of 330 children with acute appendicitis, 255 (77%) were operated by OA and 75 (23%) by LA. Catarrhal appendicitis is significantly more frequent intraoperative finding in LA (61%, p < 0.05), while phlegmonous is in OA (49%, p < 0.05). Mean operative time is 61 minutes in LA, compared with 38 minutes in OA. Mean length of hospital stay is 4.2 days after both operative techniques. Antibiotic treatment lasts as the hospital stay. Mean length of pain treatment is 1.3 days after LA and 1.5 days after OA. Conclusion: More children and especially with severe forms of acute appendicitis were treated by OA. Lesser number of patients and less severe forms of acute appendicitis were treated by LA. Total length of hospital stay, antibiotic and pain therapy are shorter in laparoscopic comparing to OA.
Pharmacovigilance for Drug Safety Monitoring

Now a day’s usage of medicine has been increasing day by day and pharmaceutical companies are developing new drug products and humans begin taking more and effective drugs as well as investigational drugs. Safety and efficacy are the two major predominant considerations about any drug. In each and every phase of a products life cycle pharmacovigilance plays a critical role. Thus, significance of pharmacovigilance is developing and became very important and inseparable part of clinical research.
Regional astrocyte interferon-γ signaling regulates immunoproteasome-mediated protection during chronic autoimmunity

In early autoimmune neuroinflammation, interferon (IFN)γ and its upregulation of the immunoproteasome (iP) is pathologic. However, during chronic multiple sclerosis (MS), IFNγ has protective properties and, the role of the iP remains to be fully elucidated. Here, we demonstrated that IFNγ signaling in regional astrocytes induces the iP and protects the CNS during autoimmunity. In MS tissue, iP expression was enhanced in spinal cord compared to brainstem lesions, which correlated with a decrease in oxidative stress. In vitro, IFNγ stimulation enhanced iP expression, reduced reactive oxygen species burden, and decreased oxidatively damaged and poly-ubiquitinated protein accumulation preferentially in human spinal cord astrocytes, which was abrogated with the use of the iP inhibitor, ONX 0914. During the chronic phase of an MS animal model, experimental autoimmune encephalomyelitis (EAE), ONX 0914 treatment exacerbated disease and led to increased oxidative stress and poly-ubiquitinated protein build-up. Finally, mice with astrocyte-specific loss of the IFNγ receptor exhibited worsened chronic EAE associated with reduced iP expression, enhanced lesion size and oxidative stress and poly-ubiquitinated protein accumulation in astrocytes. Taken together, our data reveal a protective role for IFNγ in chronic neuroinflammation and identify a novel function of the iP in astrocytes during CNS autoimmunity.
Evaluation of accuracy and precision in an amplicon sequencing workflow for marine protist communities

Advances in high‐throughput DNA sequencing methods reveal the vast diversity of marine protists. Amplicon sequencing of “barcode” genes, such as the 18S small subunit ribosomal RNA gene (henceforth, 18S gene), is a cost‐effective and widely used genetic method for assessing the composition of marine protist communities. This method is now being applied from local to global scales to interrogate the causes and consequences of protist community variations. Significant efforts have been made to validate amplicon methods targeting prokaryotes, but the precision, accuracy, and quantitative potential of 18S gene amplicon sequencing methods for marine protists remain unclear. Here, we use artificial (mock) communities and environmental samples collected from the Santa Barbara Channel, CA to evaluate the precision and accuracy in an amplicon workflow targeting the V9 hypervariable region of the 18S gene for marine protists. Overall, we find that this amplicon workflow has high precision and reasonable accuracy, but the magnitude of analytical uncertainty can increase significantly unless certain procedural issues are avoided. Finally, we demonstrate the value of positive and negative controls in, and the quantitative potential of, amplicon sequencing assessments of marine protist communities.
Effects of Regular Off-farm Activities on Household Agricultural Income: Evidence from Kenya’s Kerio Valley

This paper contributes to clarifying the scientific debate on whether off-farm activities hurt or help agricultural income in the Kerio Valley (Kenya). The main purpose of this research is to estimate the impacts of rural household’s participation in regular off-farm activities on agricultural income. The literature indicates that off-farm activities affect rural household’s income but studies on their effect on agricultural income have remained largely inconclusive. Determining how off farm activities affect agricultural income is highly relevant for the decisions of poor rural households and policy makers to allocate resources efficiently and increase investment to combat poverty. Investigation of the effects of regular off-farm activities is carried out in the following logical sequence: we performed surveys to gather information from rural households located in the Kerio Valley in Kenya; using the matching technique, we compared agricultural income per capita between households that took part in regular off-farm activities and those that did not. Methodological tools of the research were the results of a three-year project focusing on improving rural income. The object of research is the households in Kerio Valley in Kenya because they practiced the typical mix of farm and off-farm activities in rural Kenya. The empirical results of the analysis showed at first that household’s participation in regular off-farm activities had no significant effect on household agricultural income per capita. However, by splitting agricultural income into crop and livestock incomes, we found that participation in regular off-farm activities did not affect crop income per capita but it increased livestock income per capita. The results can be useful to policy makers because it shows the existence of a symbiotic association between regular off-farm activities and livestock production. The results also confirm that creating opportunities for rural households to engage in off-farm activities generates supplemental revenues, and more importantly, reliable assets. Keywords: matching technique, agricultural income, off-farm activities.
Uncovering hidden urban bounty: A case study of Hidden Harvest

Urban food systems primarily rely on foods grown in rural spaces, and often face challenges in creating spaces to grow fresh, healthful and affordable food in cities. Urban food harvest organizations aim to overcome these challenges by locating and harvesting food that already exists in cities on the numerous fruitand nut-bearing trees located on public and private lands. Hidden Harvest is a leading initiative for urban fruit and nut harvesting in Canada, and unique in its for-profit social enterprise model. The organization aims to legitimize and support the practice of harvesting fruits and nuts in urban areas and provides a means to increase access to—and availability of—fresh, healthful foods hyper-locally in Ottawa, as people harvest from their own (or nearby) neighbourhoods. This field report examines the challenges and opportunities faced by Hidden Harvest in attempting to link multiple social, environmental and economic goals relating to food sovereignty, social justice, and ecological sustainability. In particular, the organization seeks to establish a self-sustaining business model through innovative solutions and the development of networks with local food processes, food organizations, and businesses, which enables Hidden Harvest to grow and develop distinct ties and relationships in Ottawa. This case study reveals how organizations such as Hidden Harvest use food to enhance and tie together local economies, knowledge, food security and community well-being.
The Py3DViewer Project: A Python Library for fast Prototyping in Geometry Processing

Fast research and prototyping, nowadays, is shifting towards languages that allow interactive execution and quick changes. Python is very widely used for rapid prototyping. We introduce Py3DViewer , a new Python library that allows researchers to quickly prototype geometry processing algorithms by interactively editing and viewing meshes. Polygonal and polyhedral meshes are both supported. The library is designed to be used in conjunction with Jupyter environments, which allow interactive Python code execution and data visualization in a browser, thus opening up the possibility of viewing a mesh while editing the underlying geometry and topology
Recycling of concrete made with brick aggregate: An extended study

An extended study was carried out to explore the possibility of recycling of concrete made with brick aggregate as coarse aggregate. Demolished concrete blocks were collected from six demolished building sites and then crushed into coarse aggregate manually. Physical properties of the coarse aggregate collected from the blocks were evaluated. Cylindrical concrete samples (100 mm by 200 mm) were made using recycled aggregates with W/C = 0.40, 0.45 and 0.50. The specimens were tested for compressive strength, tensile strength, and Young’s modulus of concrete at the ages of 7, 14, and 28 days. Control specimens were also made using virgin brick aggregate to compare with the results of recycled aggregate. The experimental results revealed that recycled brick aggregates have lower absorption capacity compared to the virgin brick aggregate. The average strength of concrete made with recycled brick aggregate was found to be 29 MPa and 23.5 MPa for W/C=0.45 and 0.55 respectively.
Toward a mandatory public e-services in Jordan

Abstract With the rapid developments in utilizing the popularity of internet, the governments all over the world adopted various e-government projects to provide their services. This paper aimed to investigate how the governmental departments in Jordan can provide mandatory e-services to citizens. It sought to review the recent reality of the e-services provided to receivers especially among citizens by the governmental departments in Jordan. Moreover, it seeks to identify the obstacles that hinder achieving this goal. In order to deal with this issue, a thorough literature review was undertaken to identify the role of citizen’s satisfaction as well as the potential obstacles that may influence the adoption rate of e-services and therefore imposing e-services. Moreover, an investigation was conducted by analyzing the e-services provided by three major governmental departments, based on their official WebPages, and classifying them into three categories: mandatory e-services, optional e-services, tangible-optional e-services. This paper argues that the full success of e-services can be accomplished by imposing the optional e-services along with achieving the users’ satisfaction and consider it as an indicator for success. The study proposed a conceptual model that addresses the issue of imposing e-services by the governmental departments in Jordan.
Clinical Experience of Intra-Arterial Therapy in Patients with Acute Ischemic Stroke from a Single Institute

So Young Park, MD, Hanbin Lee, MD, Jonguk Kim, MD, Seung Hun Oh, MD, Jinkwon Kim, MD, Nam Keun Kim, PhD, Sang Heum Kim, MD, Ok Joon Kim, MD* 1Department of Neurology, Seoul National University-Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea Departments of 2Neurology, 4Radiology, CHA Bundang Medical Center, CHA University, Seongnam, Korea 3Institute for Clinical Research, School of Medicine, CHA University, Seongnam, Korea