Miracle-dz/UniFAR-FTUs huggingface dataset:
Fetal Toxicity and Cytotoxicity of Lannea kerstingii Engl and Krause Stem Bark ( Anacardiaceae )

Purpose: To evaluate the fetal toxicity and cytotoxicity of L. kerstingii in pregnant rats exposed in the organogenic period. Methods: Mated female rats were randomly assigned to three experimental groups of 8 animals each. Pregnant rats received orally 500 or 1000 mg/kg of 50 % hydroalcohol extract of L. kerstingii , daily from the 17th to the 20th day of gestation. On day 21 of pregnancy, the females were sacrificed. Laparotomy was performed and uterine horns were removed. The number of implants, resorptions, dead and live fetuses were then recorded. The ovaries were also observed and corpora lutea were counted. The cytotoxic effect of L. kerstingii hydroalcohol extract was evaluated on Caco-2 cell lines using MTT (3-(4, 5-dimetylthiazol-2-yl)-2, 5- diphenyltetrazolium bromide) and neutral red uptake assay. Results: No visible signs of toxicity were observed in the female rats and their pups through-out the study period. However, L. kerstingii (500 and 1000 mg/kg) caused a significant decrease (p < 0.01) in fetal weight compared with control. With regard to implantation, resorption and mortality, there was no significant difference between groups. L. kerstingii hydroal-cohol extract (IC 50 , 29 μg/mL) was more cytotoxic than the aqueous extract (IC 50 , 141 μg/mL). Conclusion: The administration of hydroalcohol extract of L. kerstingii to female rats in late pregnancy is toxic to the fetus. Keywords: Lannea kerstingii , Fetal toxicity, Cytotoxicity, Mortality, Oxidative stress, Anorexia
Application of the Precipitation-Runoff Modeling System (PRMS) to the investigation of the effects of land use changes on the runoff coefficient in the Thap Lan National Park, Prachinburi river basin, Thailand

Thap Lan National Park (TLNP) and it’s vicinities are located in the northern part of the Prajin River basin and are a famous tourist spot, as they are not too far from Bangkok, not to the least due to the beautiful mountainous scenery and the cool weather in the winter time. Unfortunately, as a caveat to this increased tourist attraction, the tourism service sector in TLNP has been steadily expanded in recent years, with partly illegal deforestation, intrusion and build-up of resorts and/or hotels. Thus, land use in that area has changed to a certain degree. Moreover, as this part of the TLNP, because of its hill-slope topography, acts as a recharge area for the Prajin River basin, the hydrology of the latter may have been affected as well. One parameter to quantify the hydrological consequences of these land-use changes in the TLNP is the runoffcoefficient (C). For its computation the PRMS-model was set up for the whole Prachinburi River basin and calibrated with meteorological and discharge data for the time period 1993–2012 and the recent land-use. The results show that PRMS has an acceptable performance in simulating the monthly runoff in the study area and, consequently, also the runoff-coefficient in the TLNP area, which on annual average, turns out to be C = 0.21 for the time period considered. Starting from this base scenario, and extrapolating the above-mentioned land-use change in the TLNP to some extreme deforestation, PRMS was applied again to simulate the ensuing hydrological effects. A change of C from C = 0.21 to C = 0.28 is obtained, i.e. an increase of the average annual runoff by 33%. For some months of the year, namely, at the end of the dry season in late spring, the runoff for this adverse scenario is augmented by an even higher rate of more than 100%. All these run-off increases go, obviously, hand in hand with corresponding decreases of the groundwater recharge of the basin which indicates that its hydrological water budget would be significantly altered by such extreme land-use changes in the TLNP area.
Isolation of Escherichia coli and Salmonella Spp from Dead in Shell Embryos of Chicken

1 Department of Physiology, Biochemistry & Pharmacology, Chittagong Veterinary and Animal Sciences University, Khulshi, Chittagong, Bangladesh 2 Department of Microbiology, University of Chittagong, Chittagong, Bangladesh 3 Department of Medicine and Surgery, Chittagong Veterinary and Animal Sciences University, Khulshi, Chittagong Bangladesh 4 Department of Aantomy and Histology, Chittagong Veterinary and Animal Sciences University, Khulshi, Chittagong Bangladesh
Milk production and quality of Etawa crossbreed dairy goat that given Tithonia diversifolia, corn waste and concentrate based palm kernel cake

Abstract. Arief, Rudimansyah, Sowmen S, Rizqan RP. 2020. Milk production and quality of Etawa crossbreed dairy goat that given Tithonia diversifolia, corn waste and concentrate based palm kernel cake. Biodiversitas 21: 4004-4009. The research aims to evaluate the production and quality of goat milk of Etawa crossbreed dairy goat (ECDG) which is fed by Tithonia diversifolia (T), corn waste (CW), and concentrate-based palm kernel cake (CBP),. The experimental design used in this study was a completely random design (CRD) with four times treatment rations and five times replications. There are five treatments used in this research which are; treatment A used 60 % T + 40 % tofu-dregs; B used 60 % T + 20% tofu-dregs + 20% CBP; C used 45 % T + 15% CW + 20% tofu-dregs + 20% CBP; D used 30 % T + 30% CW + 20% tofu-dregs + 20% CBP. The data were analyzed by Analysis of Varian (ANOVA) and Duncan's Multiple Range Test (DMRT) for further tests. The parameters measured were milk production and milk quality, which covers dry matter, water content, protein, fat, solid non-fat, and lactose. The result showed that the treatment gave no significant effect (P> 0.05) of milk production, dry matter, protein, fat, solid non-fat, and lactose. The study concluded that the use of T. diversifolia, corn-waste, and CBP could maintain milk production quality.
Study on the microbiological degradation of bensulfuronmethyl

Studies on the microbiological degradation of bensulfuron methyl in anaerobic conditions have made it possible to define the best operative conditions for its biodegradation and the isolation and identification of metabolites. Chemical degradation, typical of all the sulfonylureas, contributes to about 30% of the transformation of bensulfuronmethyl, whilst abiotic factors do not appear to play any role in the herbicide degradation. Biodegradation in anaerobiosis is particularly active in methanogenic conditions, though the bensulfuron methyl transformation would not seem to be due to direct action of only methanobacteria given the excessive complexity of the molecule. The extraction of the products from the culture medium led to the isolation of two pure metabolites that were characterized by 1 H-NMR. The O-demethylation seems to be the first step in the degradation that occurs in successive times at the expense of both the substituents of the pyrimidic ring. The investigation into the biodegradation course evidenced that the transformation of bensulfuronmethyl takes place quickly in the first 20 days and slows down until it stops completely after 40 days.
Goat Farming Systems in Eravur and Vantharumoolai Veternery Ranges in Batticaloa District: Feeding and Management Strategies

DOI: 10.21276/sjavs.2018. 5.8. 6 Abstract: A survey was conducted to investigate the features of goat farming in Eravur and Vantharumoolai veterinary ranges in Batticaloa district, Sri Lanka. A pre-tested structured questionnaire was designed and 200 goat farmers were randomly interviewed. The data were coded, entered in Microsoft Excel and transferred into SPSS for analysis. Farmers exhibited limited knowledge on goat farming and improved management. They reared goats mainly for commercial purpose. Heard size was generally 11-20 and majority of the farmers kept indigenous and cross breeds of goats. Farmers reared goats mostly for meat purpose in both veterinary ranges and 5% of the farmers from Vanthrumoolai range reared goats for milk purpose. All the framers in both range used proper housing systems foe goats. Semi-intensive system of goat rearing was practiced by 70% of the farmers in Eravur range and 42.5% of the framers in Vantharumoolai range. Natural breeding was the prominent method of breeding in both ranges (100%). In Eravur and Vantharumoolai ranges goats were allowed to graze for more than 8 hours sper day and fodder tree, fodder grass, concentrate and crop residues were used as feed sources in both ranges. In Eravur and Vantharumoolai ranges 92.5% and 97.5% of the meat was sold to middle man respectively. Veterinary service was good and adequate for both ranges and there are some constrains in both ranges.
Mechanical Properties and Drying Shrinkage Investigation of Alkali-Activated Mortar Using Waste Glass Powder

Alkali-activated mortar (AAM) is one of the products of waste glass recycling that exhibits promising potential for wide engineering applications such as the construction industry. In this study, recycled waste glass powder-based additives, namely, Silica Fume (SF) and Nano-SiO2 (NS), were investigated for their potential to enhance the mechanical properties (strength) and drying-shrinkage resistance of AAM. The results indicated that 5.0% and 1.5% were the optimum SF and NS dosages, respectively, for optimizing AAM performance in terms of the compressive strength, flexural strength, and drying-shrinkage resistance. A prediction model, based on backpropagation (BP) neural network analysis, was also satisfactorily formulated and preliminarily validated for predicting the drying shrinkage of AAM containing SF or NS.
MODELING ALLOCATION OF HIVES

The contribution of insect pollinators to the economic output is obvious. Several alternative bee species have been identified to be capable of replacing or at least supplementing decreasing number of honey bees. Our research aim to deal with location of nesting aids for solitary bees in orchards using mathematical programming models for determining the optimal location of nesting aids and thus can be used to optimize the management of solitary bees.
Study of Flavonoids from Seed Residues of Hippophae rhamnoides L. on Apoptosis of Human Mammary Carcinoma Bcap-37 Cells

To investigate the effect and mechanism of apoptosis of human mammary carcinoma Bcap-37 cells induced by flavonoids from seed residues of Hippophae rhamnoides L. (FHR). Bcap-37 cells were treated by different concentration of FHR at diverse time periods, which was identified by MTT, Wright staining, flow cytometry and immunohistochemical methods. The experiments showed that FHR can induce Bcap-37 cells undergoing apoptosis within 10-1000 μg/mL, its apoptotic symptom depends on dose (FHR) and time gradient; the cell cycle of Bcap-37 cells was affected when it was treated 24 h, 28 h and 72 h with 1000 μg/mL FHRi S phase reduced, and G0/G1 increased; compared with the control group, the expression of p53 protein increased and bcl-2 protein decreased in Bcap-37 cells treated with FHR. These results suggest that FHR can trigger growth inhibition on Bcap-37 cells in vitro by inducing apoptosis, meanwhile the increase of p53 protein and decrease of bcl-2 protein is one of the reasons on mechanism of apoptosis.
Strengths and Weaknesses of Cognitive Theory

This paper focuses on strengths and weaknesses of the Cognitive Theory. Many theories have been proposed over the years to explain the developmental changes that people undergo over the course of their lives. These theories differ in the conceptions of human nature they adopt and in what they regard to be the basic causes and mechanisms of human motivation and behavior. Piaget's theory of cognitive development explains how a child constructs a mental model of the world. He disagreed with the idea that intelligence was a fixed trait, and regarded cognitive development as a process which occurs due to biological maturation and interaction with the environment. Cognitive learning theory is best used to guide learning when trying to build usefulness Knowledge structures, and clinical reasoning teaching. The theory suggests that Clinical exercise is crucial to the organization of Memory Knowledge and Recall Facilitation. This means teachers will be expected to be aware of prior clinical experiences of the learner before assessing the learner’s experience Powerful performance.
Who killed Bambi? The role of predation in the neonatal mortality of temperate ungulates

A total of 111 papers and reports, coming from 79 major studies and 19 other studies, on neonatal (first summer) mortality of 10 species of northern, temperate ungulates were reviewed. To avoid biases from indirect techniques only studies on radio-collared neonates and/or their dams were included, apart from a few notable exceptions. Neonatal mortality rates observed for different studies averaged 47% (68 studies) in environments where predators occurred, with predation accounting for an average of 67% (53 studies) of this mortality. No other single cause of mortality exceeded that of predation, which accounted for 0–100% of the mortality recorded in various studies. In contrast, mortality averaged 19% for studies in environments lacking predators. Other prominent causes of mortality were hypothermia/starvation and accidents. Disease was found to play a small role only. The predator species involved varied greatly between study areas, with both medium sized (bobcat Lynx rufus, Canada lynx Lynx canadensis, coyote Canis latrans and red fox Vulpes vulpes) and large (wolf Canis lupus, mountain lion Felis concolor, black bear Ursus americana and brown bear Ursus arctos) terrestrial predators preying upon the neonates. Despite the prominent role of predation, little is known about its long-term compensatory or additive nature, and therefore its impact on population dynamics is unclear. Factors influencing predation rates are poorly understood, although a few studies found significant sex-biased predation, and effects of weather or juvenile/maternal body condition. Timing of mortality within the first summer varied with the predators involved and the neonatal security strategy of the species, but was not confined to the immediate post-partum period.
Influence of Cultural Nuances in Buying Decision of Customers for Leisure Hotels in Enugu State, Nigeria

This study was carried out to determine the influence of cultural nuances in buying decision of customers for leisure hotels. A sample size of 375 was determined from the population of 6000, through a statistical tool. A structured questionnaire was used to collate data. Data collated was analyzed using frequency and percentage. Respondents revealed very positive response to the variables in each of the objectives in the analysis, which revealed that the variables were agents of buying decision of customers for leisure hotels. Recommendations were made in line with the findings of the research.
탄소원에 따른 Bacterial Cellulose의 물성

Bacterial cellulose는 초산균인 Cluconacetobacter xylinus에 의해 생산되며. 배양 배지의 표면에 나노섬유상의 막을 형성한다. 본 연구에서는 배지의 조성에서 탄소원을 달리하여 생산한 bacterial cellulose의 결정화도 점도 모폴로지와 역학적 물성을 살펴보았다. Cluconacetolbactersp. V6 균은 세 종류의 배양 배지에서 정치 상태로 배양되었다. 배양 배지로는 표준 Hestrin-Schramm 배지와 탄소원으로 glycerol 또는 molasses를 첨가한 개젤 배지가 각각 시용되었다. 세포 성장과 셀룰로오스 수율은 molasses 배지와 glycerol 배지에서 증가하였다. Glycerol 배지를 사용한 배양은 결정화도와 고유점도, 파단응력과 같은 셀룰로오스의 물성을 향상시켰으나 molasses 배지를 사용한 배양은 셀룰로오스의 결정화도 미결정의 크기, 고유점도를 감소시켰다 요약하면, molasses 배지에서 셀룰로오스의 수율은 현저히 향상되었으나, 낮은 구조적 물성을 가졌다.
Development and Quality Evaluation of Ready to Serve (RTS) Beverage from Banana Pseudo Stem

Vegetable beverage was part of a balanced diet that make sure the vigor and healthy body. Vegetable juices were rich in fiber content which was quickly inducing the feeling of satiety and also improve digestion. The objective of this study was to formulate and prepare ready to serve (RTS) banana pseudo stem beverage. Two banana varieties were selected viz., ottu vazhai (syn Mupaddai) (V1), vayal vazhai (V2). Banana pseudo stem beverage was developed from banana tender core, natural flavorings (lemon, mint)extracts, 2% citric acid as a anti-browning agent, KMS (70ppm) as preservative and CMC (0.1%) as a stabilizer. The proximate composition, physico- chemical analysis, sensory evaluation and microbial study of the pseudo stem beverage was evaluated using standard procedures. The beverages were evaluated at 15 days interval period. During storage conditions the quality of juice with minimum significant changes in chemical properties was observed with the addition of KMS. Based on the sensory evaluation, lemon juice flavored pseudo stem beverage was highly accepted by consumer than mint flavored beverage. Storage study for the pseudo stem beverage was also carried out and significant difference was noticed in beverage. Compare to vayal vazhai (V2), the yield of juice (87.0%) content was higher in ottu vazhai (syn Mupaddai) (V1). The maximum desirable results were obtained from (V1) lemon flavored beverage stored at refrigeration condition. The results were showed that pH (3.28 to 4.75), TSS (12 to 14.0° brix), Acidity (0.35 to 0.26) and vitamin C (0.77 to 0.59). From the storage studies, the lemon flavored pseudo stem beverage (Mupaddai variety V1) was found to be the best in nutrient retention and sensory evaluation than mint flavour beverage and it was accepted up to 45 days.
Generating Globally Coherent Original Melodies Using LSTMs and music21

Machine learning algorithms have increasingly been implemented in a variety of ways within the music domain. In this paper, a Long Short Term Memory Network (LSTM) was used to solve the music-related problem of composition. The network was trained on ”Ryan’s Mammoth Collection of Fiddle Tunes” which was obtained from the music21 corpus. Previous attempts to generate melodies using neural networks have suﬀered from a lack of ”global coherency”. All networks were able to learn key. The 256 time step network produced melodies that were the most globally coherent, however the computer-generated melodies were not judged to be as globally coherent as the melodies in the training set.
APPLYING LEARNING METHODS WITH ARCHITECTURESTUDENTS TO IMPROVE INDOOR QUALITY FOR HEALTH ANDWELLBEING IN BUILDINGSCASE STUDY: ENHANCING LIGHTING EFFICIENCY OF PUBLICSPACES

The teaching-learning methods and techniques that can be applied in architecture are various, such as project-based learning, problem-based learning, research-based learning, problem-solving, simulationbased learning, designbuild and others. The researcher aims at experimenting and applying such methods in a design class at Faculty of Architecture to manage and improve the environmental quality of the public spaces that will increase the awareness of health and wellbeing aspects of the students. Therefore, the study aims to produce a new methodology for integrating different teachinglearning methods in the interior design course and evaluate the outcomes of the students according to the indoor lighting performance. The case study is based on a real problem in a realistic situation City Complex Shopping Mall in Tripoli, Lebanon in which the instructor and the students will analyze and measure the intensity of lighting within the mall atrium, and the extent of its reflection on the validity and functional efficiency of the building. The students with the aid of their instructor will use the Testo Light Meter/Logger and the Echotect Analysis 2010 Software as tools of measurement, simulation and development. The paper proposes successful methods to achieve special criteria for developing indoor quality to increase health and wellbeing aspects of building in general, and produce solutions for improving lighting efficiency of public spaces in particular. Through integrating different teaching-learning methods, the instructor develops and integrates appropriate techniques that will help in monitoring, improving and achieving optimal outcomes of the students' designed proposals, thereby ensuring high educational performance.
ORCHESTRA a Uniﬁed an Open Architecture for Risk Management Applications

Risk management activities involve a range of different organisations at various administrative levels with their own systems and services. However, the sharing of relevant information that is required for dealing with risks is often limited to a mere raw data exchange. Thus, true efﬁciency, in most cases, is hindered by administrative and legal boundaries as well as a lack of interoperability on the technical side. Furthermore, the application of numerous and different policies, procedures, data standards and systems, results in co-ordination problems with respect to data analysis, information delivery and resource management, all critical elements of risk management
Distributed Many-to-Many Protein Sequence Alignment using Sparse Matrices

Identifying similar protein sequences is a core step in many computational biology pipelines such as detection of homologous protein sequences, generation of similarity protein graphs for downstream analysis, functional annotation, and gene location. Performance and scalability of protein similarity search have proven to be a bottleneck in many bioinformatics pipelines due to increase in cheap and abundant sequencing data. This work presents a new distributed-memory software PASTIS. PASTIS relies on sparse matrix computations for efficient identification of possibly similar proteins. We use distributed sparse matrices for scalability and show that the sparse matrix infrastructure is a great fit for protein similarity search when coupled with a fully-distributed dictionary of sequences that allow remote sequence requests to be fulfilled. Our algorithm incorporates the unique bias in amino acid sequence substitution in search without altering basic sparse matrix model, and in turn, achieves ideal scaling up to millions of protein sequences.
Plasma AR Copy Number Changes and Outcome to Abiraterone and Enzalutamide

Introduction: Plasma androgen receptor (AR) copy number (CN) status identifies castration-resistant prostate cancer (CRPC) patients with worse outcome on abiraterone/enzalutamide. However, the impact of AR CN changes on clinical outcome in CRPC is unknown. Materials and Methods: Plasma samples from 73 patients treated with abiraterone or enzalutamide were collected at baseline and at the time of progression disease (PD). Droplet digital polymerase chain reaction was used to assess AR CN status. Results: We showed that 11 patients (15.1%) changed AR CN status from baseline to PD (9 patients from normal to gain, 2 from gain to normal). Patients changing AR CN status from normal at baseline to gain at PD had intermediate median overall survival (OS) of 20.5 months (95% CI = 8.0–44.2) between those who remained AR CN normal from baseline to PD (27.3 months [95% CI = 21.9–34.4]) and those who remained AR CN gain from baseline to PD (9.1 months [95% CI = 3.8–14.5], p < 0.0001). Patients changing AR CN from normal at baseline to gain at PD had a median progression-free survival (PFS) of 9.2 months (95% CI = 2.0–14.7), patients who remained AR CN normal had a median PFS of 9.1 months (95% CI = 7.2–10.1), and patients who remained AR CN gain had a median PFS of 5.4 (95% CI = 3.6–6.5, p = 0.0005). Both OS and PFS were not significantly different between patients with AR CN that changes from normal to gain and patients with stable AR CN normal. Conclusions: We showed that CRPC patients changing AR CN status from baseline to progression time point had intermediate OS and we suggested that AR CN evaluation at baseline could be the most informative for clinical outcome of CRPC patients treated with abiraterone or enzalutamide. Larger prospective studies are warranted.