Akciğer Lezyonu Olan Hastaların Aspirasyonsuz İnce İğne Sitolojisi ile Tanısı: 10 Vaka Raporu ile Literatür / Değerlendirmesi Diagnosis of Patients with Lung Lesions By Fine Needle Nonaspiration Cytology: Ten Cases Reports And Review of The Literature

Ozet: Periferik lenf nodu veya lezyona yonelik ince igne aspirasyonunun (IIA) non invaziv bir inceleme yontemi oldugu ve sitopatolojik tani sagladigi onceki calismalarla gosterilmistir. Burada geleneksel emici kuvvet uygulamasi ile yapilan ince igne aspirasyonu degil de aspirasyonsuz ince igne sitolojisinin (AIIS) kanser teshisinde tani ve evrelemeye katkisini vurgulamayi amacladik. Akcigerde kitlesi olan 10 olguda periferik lenf nodu veya akcigerdeki periferal kitlelere uygulanan AIIS’nin sonuclari degerlendirilmistir. On hastanin (1’i kadin 9’u erkek), yas ortalamasi 59 (35-84) yil idi. Periferik lenf nodu saptanan 7 hasta ile periferik yerlesimli akciger lezyonu olan 3 hastaya AIIS yapildi ve yaymalar degerlendirildi. Periferik lenf nodu ve periferik kitleden AIIS yapilan 10 hastanin 2’si skuamoz hucreli karsinom, 4’u kucuk hucreli disi akciger karsinomu, diger 4’u ise malignite pozitif olarak tani aldi. Malignite pozitif saptanan 4 hastadan 2’si bronkoskopi ile skuamoz hucreli karsinom ve kucuk hucreli karsinom tanilari alirken 2‘si trucut biyopsi ile skuamoz hucreli karsinom ve lenfoma tanilari aldi. Lenf nodu ve periferik lezyondan yapilan AIIS taninin yaninda akciger kanserli hastalarda evreleme acisindan da fayda sagladi. Sonuc olarak periferik olarak tumor veya tumor metastazina ulasilabilen hastalarda AIIS yapilmasi kolay ve etkin bir yontemdir. Tani yaninda tumor non-rezektabilitesi degerlendirmede ve diger ayirici tanilarda da faydalidir. Bu nedenle AIIS lezyonu uygun olan ve ozellikle invaziv islemler acisindan risk tasiyan hastalarda baslangic noninvaziv tani yontemi olabilir. Sitoblok yontemleriyle taniyi artirmak mumkundur. Anahtar Kelimeler: aspirasyonsuz ince igne sitolojisi, periferik lenf nodu, periferik akciger lezyonu Abstract: Fine needle aspiration (FNA) for peripheral lymph node or lesion was shown a non-invasive method that provides cytopathologic diagnosis with previous studies. We aimed to emphasize the contribution of fine needle nonaspiration cytology (FNNAC) not FNA performed by traditional suction force in diagnosis and staging of cancer. The results of FNNAC performed to the peripheral lymph nodes and lesions were evaluated in 10 cases with pulmonary mass. The mean age of 10 patients (1 was female, 9 were male) was 59 (35-84) years old. FNNAC was performed 7 of patients with peripheral lymph node, 3 of patients with peripheral lesion and, slides were evaluated. FNNAC was performed in 10 patients who 2 were diagnosed as squamous cell carcinoma (SQCLC), 4 were diagnosed as nonsmall cell lung carcinoma and 4 were diagnosed as positive malignancy. Two of 4 patients reported with positive malignancy were diagnosed as SQCLC and small cell carcinoma with bronchoscopy, while the other 2 were diagnosed as SQCLC and lenfoma with trucut biopsy. FNNAC performed on peripheral lymph nodes and lesions has provided benefits in terms of staging while confirmed the diagnosis. FNNAC is a simple and reliable method in patients whose tumors or tumor metastasis are available peripherally; in addition to tumor diagnosis it might be helpful for the evaluation of non-resectability and other differential diagnosis. FNNAC can be initial non-invasive diagnostic method especially in appropiate lesions and in patients with risk factors for invasive process. It might be possible to increase the diagnosis with cytobloc methods. Keywords: fine needle nonaspiration cytology, peripheral lymph node, peripheral lung lesion