Miracle-dz/UniFAR-FTUs huggingface dataset:
Entrepreneurial passion and the acquisition of financial resources in Crowdfunding.

We investigate the role of entrepreneurial passion displayed through affective passion and preparedness as a persuasive mechanism conducive to support in crowdfunding. We assess the emotion cues contained in the language of the entrepreneurial narratives by means of content analysis. Results of probit model estimates on more then 14,000 Kickstarter campaigns show that affective passion and preparedness increase the likelihood of success of +15.1% and +8.2% respectively. Moreover, the effect of entrepreneurial passion is stronger when the information is provided in a context of low ambiguity and the effect of preparedness is stronger when the language is less complex.
Conditional senescence in bacteria: death of the immortals

Like ageing insects, worms and mammals, growth‐arrested Escherichia coli cells accumulate oxidatively damaged proteins. In the early stages of the E. coli stationary phase, this oxidation is caused by an increased production of aberrant proteins, which are especially susceptible to oxidative attack. This route of oxidation appears to elude the classical oxidative defence proteins. The failure of growth‐arrested cells fully to combat oxidative damage may also be linked to a trade‐off between proliferation activities (primarily directed by the housekeeping sigma factor, σ70) and maintenance (primarily directed by σS). This trade‐off is regulated by the alarmone ppGpp such that elevated ppGpp levels allow σS, and other alternative sigma factors, to work in concert with σ70 by shifting their relative competitiveness for RNA polymerase binding. However, even during elevated ppGpp levels and stasis, E. coli cells maintain a basal transcription of housekeeping σ70‐dependent genes, and resources are thus partly diverted from maintenance and stress defences to activities relating to proliferation. An alternative view argues for ppGpp being involved in programmed cell death upon growth arrest by regulating chromosomally located toxin–antitoxin loci. Thus, models of bacterial senescence, like those dealing with ageing in higher organisms, encompass both stochastic deterioration theories and programming theories. This review summarizes and evaluates these models.
E-Government Adoption Research: Analysing challenges and Critical Success Factors

After more than a decade of research in the area of e-government adoption research, no study has performed a literature analysis on the specific aspects of e-government adoption such as challenges and critical success factors. The purpose of this paper is to analyse the studies on challenges and critical success factors of e-government adoption research to suggest the future researchers about the salient facts about it. This study can help the researchers to evaluate the challenges and factors required for the successful implementation of e-government services in the different circumstances. This literature analysis was performed through filtering the usable studies specifically on challenges (C=43) and critical success factors (C=8) from an overall research studies (C=448) on e-government adoption research. The findings indicated that digital divide, poor management and infrastructure, ICT related challenges, lack of resources, lack of trust, privacy and security, and technical challenges were among the most commonly experienced challenges across the relevant studies. Moreover, user satisfaction, information accuracy, and security were few common critical success factors. The paper also acknowledges the limitations of this research and suggests further research directions for the researchers.
TEAMcare: An Integrated Multicondition Collaborative Care Program for Chronic Illnesses and Depression

Patients with poorly controlled diabetes, coronary heart disease, and depression have an increased risk of adverse outcomes. In a randomized, controlled trial, we tested an intervention designed to improve disease control outcomes for diabetes and/or heart disease and coexisting depression. Patients with one or more parameters of poor medical disease control (ie, HbA1c ≥8.5, or SBP >140, or LDL >130) and a Patient Health Questionnaire-9 (PHQ-9) ≥10 were randomized to the TEAMcare intervention or usual care (N = 214). This article will describe the TEAMcare health services model that has been shown to improve quality of care and medical and psychiatric outcomes.
A comparison of hemodynamic data derived by pulmonary artery flotation catheter and the esophageal Doppler monitor in preeclampsia.

OBJECTIVE This study was undertaken to compare hemodynamic data derived with the esophageal Doppler monitor against those obtained with a pulmonary artery flotation catheter in women with complicated preeclampsia. STUDY DESIGN Seventeen women with severe preeclampsia who had a pulmonary artery flotation catheter placed for clinical indications also had an esophageal Doppler monitor inserted. Hemodynamic data were recorded on 2 occasions separated by several hours with both the pulmonary artery flotation catheter and the esophageal Doppler monitor simultaneously. RESULTS The esophageal Doppler monitor underestimated cardiac output by 36% +/- 14% (mean +/- SD). The esophageal Doppler monitor accurately estimated cardiac output in 3 women >40 years old, whereas in the remaining women (all <35 years old) the esophageal Doppler monitor underestimated cardiac output by 38% +/- 11%. The esophageal Doppler monitor accurately reflected changes in cardiac output with time when compared with the pulmonary artery flotation catheter. CONCLUSION In women with preeclampsia the esophageal Doppler monitor consistently underestimated cardiac output by approximately 40%. It is not known whether the apparent increase in accuracy among the women >40 years old arose by chance or reflected a real improvement in performance. The esophageal Doppler monitor accurately reflected the direction and magnitude of the changes in cardiac output with time.
Influence of pesticide exposure on carbonic anhydrase II from sheep stomach

Carbonic anhydrase (CA) is a widely distributed enzyme and has a crucial role in the cells, tissues and organs of living organisms. It is found that CA-II is one of the most abundant CA isoenzymes in the gastrointestinal system. It plays an important role in the gastric acid secretion in stomach. In this study, we purified CA-II isoenzyme from sheep stomach with a 615.2 purification fold, 78% purification yield and 5562.02 specific activity. Moreover, the in vitro effects of some commonly used pesticides including chlorpyrifos, cypermethrin, dichlorvos, glyphosate isopropylamine and lambda cyhalomethrin on the enzyme activity were investigated. Of these compounds, glyphosate isopropylamine and dichlorvos showed an inhibition on CA-II esterase activity. They have IC50 values of 0.155 µM and 2.690 µM and Ki values of 0.329 µM and 3.654 µM, respectively. Both glyphosate isopropylamine and dichlorvos inhibited CA-II isoenzyme in a noncompetitive manner.
Ankle systolic pressure measurements in arterial disease affecting the lower extremities

continuity, achieved by the inverting technique than REFERENCES by alternative procedures. CAMERON, G. R. , and KHANNA, S. P. (I959),3. Path. Bact. , Mucosal regeneration was also superior in inverted anastomoses and was apparently related to the HARGREAVES, A. w. , and KEDDIE, N. c. (I968), Br. J . relatively smaller amounts of intervening granulation tissue in animals of this group as compared with those “:? ;Til. ~ ; p M ~ o ~ ; ~ , a ~ d 5 0 J s S H ” . F. R. (1958)y 3. of other groups. -and MITCHELL, J. E. (1954),3. Anat. , 88, 99. In the immediate Postoperative period serosal MELNYK, C. S. , BRAUCHER, R. E. , and KIRSNER, J. B. inflammation, due to leakage from the anastomosis, was greatest in animals treated by the everting method. O’CONNOR, . J. (1954), Br. J. exp. Path. , 35, 545. 77, 505.
When must a patient seek healthcare? Bringing the perspectives of islamic jurists and clinicians into dialogue

Muslim physicians and Islamic jurists analyze the moral dimensions of biomedicine using different tools and processes. While the deliberations of these two classes of experts involve judgments about the deliverables of the other's respective fields, Islamic jurists and Muslim physicians rarely engage in discussions about the constructs and epistemic frameworks that motivate their analyses. The lack of dialogue creates gaps in knowledge and leads to imprecise guidance. In order to address these discursive and conceptual gaps we describe the sources of knowledge and reasoning employed by Islamic jurists and clinicians to resolve the question of when a patient must seek healthcare. As we examine both the scriptural evidence and legal reasoning of jurists and the types of medical evidence used by clinicians to address the same question, we draw attention to the epistemic frameworks and constructs at play and identify how constructs from one field may sharpen the deliberative exercises of the other. Hence our work advances discourses at the intersection of Islam and medicine and offers building blocks for a comprehensive Islamic framework that fully integrates the deliverables of medical science within the deliberations of Islamic jurists.
Kinematics of the transition between aquatic and terrestrial locomotion in the newt Taricha torosa

SUMMARY California newts (Taricha torosa) are capable of locomotion in both aquatic and terrestrial environments. The transition between swimming and terrestrial walking was examined by videotaping individual Taricha walking both up and down a ramp, inclined at 15° to the horizontal, that had its lower end immersed in water and its upper end out of the water. When ascending the ramp, California newts first approached it by swimming, then used their limbs to walk while still in water, and finally left the water using a normal terrestrial walking gait. The reverse of this sequence was observed when individuals descended the ramp. In both directions, Taricha used a lateral sequence walk with a duty factor of approximately 76% when out of the water. Timing of footfalls was more variable in water and featured shorter duty factors, leading to periods of suspension. Comparison of angular and timing variables revealed effects due to direction and degree of immersion. Few timing variables showed differences according to stride within sequence (indicating whether the animal was in or out of the water), suggesting that the basic walking pattern is equally good in both environments.
Patterns of Supply Chain Integration in a Service Setting: Antecedents and Relationship Effectiveness

Using three process dimensions of integration, we study patterns of supply chain integration, how they are supported, and how they influence the relationship effectiveness. Hypotheses are developed using the Transaction Cost Theory, and tested with data from 171 pharmacies. Knowledge of factors that facilitate integration should help improve pharmacy-wholesaler relationships.
Immunotoxicity of Perfluorinated Compounds: Recent Developments

Perfluorinated compounds (PFCs) are environmentally widespread, persistent, and bioaccumulative chemicals with multiple toxicities reported in experimental models and wildlife, including immunomodulation. The two most commonly detected compounds, which also generally occur in the highest concentrations in environmentally exposed organisms, are perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS). PFOA and PFOS have been reported to alter inflammatory responses, production of cytokines, and adaptive and innate immune responses in rodent models, avian models, reptilian models, and mammalian and nonmammalian wildlife. Mounting evidence suggests that immune effects in laboratory animal models occur at serum concentrations below, within the reported range, or just above those reported for highly exposed humans and wildlife. Thus, the risk of immune effects for humans and wildlife exposed to PFCs cannot be discounted, especially when bioaccumulation and exposure to multiple PFCs are considered. This review contains brief descriptions of current and recently published work exploring immunomodulation by PFOA, PFOS, and other PFCs in rodent models, alternative laboratory models, and wildlife.
Predictors of recurrent stroke in African Americans

Background: Stroke incidence and mortality are disproportionately higher among African Americans than among whites. Objective: To describe the recurrent stroke characteristics and determine the predictability of known vascular risk factors for stroke recurrence in African Americans. Methods: The authors followed 1,809 African Americans in the African-American Antiplatelet Stroke Prevention Study with recent noncardioembolic ischemic stroke for recurrent stroke, recurrent stroke subtype, and disability. Results: Of the subjects, 10.6% experienced a recurrent stroke during follow-up. The mean interval between eligibility and recurrent stroke was 325 days (median 287 days, SD = 224 days). Stroke recurrence resulted in an average 1.5-point increase in the National Institute of Health Stroke Scale (p < 0.001) and a 3.5-point decrease in modified Barthel Index (p < 0.001). Of previously nondisabled subjects, 48% became disabled or died after stroke recurrence (p < 0.0001). Longitudinal analysis resulted in a hazard for recurrent stroke for each 10-mm Hg increase in systolic blood pressure of 1.103 (95% CI: 1.031 to 1.179, p = 0.004), pulse pressure 1.123 (95% CI: 1.041 to 1.213, p = 0.003), and mean arterial pressure 1.123 (95% CI: 1.001 to 1.260, p = 0.048). Multivariate analysis revealed increases in the recurrent stroke hazard for increases in baseline Glasgow Outcome Score (1.449, 95% CI: 1.071 to 1.961, p = 0.016) and increases in longitudinal pulse pressure (1.009, 95% CI: 1.001 to 1.017, p = 0.029). Conclusion: Recurrent stroke leads to disability and disability predicts recurrent stroke. Hypertension is the most predictive modifiable stroke risk factor.
Female epispadias: are we missing the diagnosis?

To describe three of four female patients with occult epispadias, as usually epispadias is reported to be a rare condition in females (1/480 000), and obvious and easy to diagnose, but less severe variants may still involve urethral sphincter incompetence in the absence of obvious clinical signs.
Preliminary investigation on bearing fault analysis in three phase induction motor by MEMS accelerometer

This paper proposes a simple method to detect single point defect in inner race of the bearing of smaller horse power induction motor by employing motor vibration and current signals. Experimental investigations have been carried out under no load, full load and unbalance voltage conditions. The effect of inner race bearing fault on the air gap length modulation has been investigated. The spectral analysis of both vibration and current signal has been carried out by using radix-2 decimation in time fast Fourier transform (DIT-FFT) algorithm. The results of both the methods are compared with theoretical values and found to be closely matching. This indicates that proposed method can be used as an alternative to conventional vibration and current signature analysis for condition monitoring of bearings.
ANALYSIS OF THE RELATIONSHIP BETWEEN E-SERVICE QUALITY, CUSTOMER SATISFACTION, AND CONSUMER BEHAVIORAL INTENTIONS: A CASE STUDY OF ONLINE-BASED AGRIBUSINESS COMPANIES IN MALANG CITY

The trend of internet uses in daily activities causes changes in the way business and society work. Business owners are now competing to offer better products and switch to online transactions. This intense competition causes marketers to find ways to be able to compete. In terms of e-commerce, the quality of service is the main factor of a successful e-business. The purpose of this study is to analyze the relationship between e-service quality, customer satisfaction, and consumer behavioral intentions. The data was obtained from 41 online shop consumers through an online survey using structural equation modeling (SEM). The results showed that positive evaluation of e-service quality will positively impact customer satisfaction and behavioral intention. Customer satisfaction also has a positive impact on consumer behavioral intention. This study suggests that practitioners use the model to allocate resources to essential quality attributes, or those that are low-performance, which is needed to improve customer satisfaction and positive consumer behavioral intentions.
Locational signal for TTC investment by sensitivity calculation

The zonal approach is now broadly adopted by electricity markets worldwide, since it provides the participants with an easily understandable representation of the transmission constraints. The zonal approach and the total transmission capability (TTC) interact in the sense that the higher is the TTC, the lower is the influence of transmission constraints on market results. As a consequence the TTC value is one of the most important issues in a liberalized environment. Its improvement is crucial for the market: it is typically pursued by investments on new branches. The effectiveness of a new line can be measured by evaluating its ability to relieve the transmission constraints that currently limit the TTC: since an exhaustive analysis of this problem would entail an unacceptable computation burden, a new approach based on a sensitivity approach is used to identify possible new lines for planning purposes The related benefits are eventually evaluated by effectively computing the relevant TTC. The effectiveness of this new approach is successfully proved on the Italian transmission network.
Design of closed-loop feedback control system for mini greenhouse illumination based on PWM

Because of the illumination adjustment problem of seedling cultivation in mini greenhouse, a closed-loop feedback control system is proposed to control illumination based on PWM in this paper. This system is composed of single chip, buck circuit, PWM circuit based on DC-DC, LED, feedback circuit of illumination collection, and LCD1602 display circuit. In order to achieve intelligent adjustable light source, The single chip output adjustable PWM to control the current strength to control the led illumination, and The illumination is instantaneously fed back to the single chip via a light sensor for processing to meet the different illumination requirements of each growth stage of the plant. The system proves that the design can solve the illumination control problem in mini greenhouse, and it has real-time feedback and adjustment function.
PET imaging for brain tumor diagnostics.

PURPOSE OF REVIEW Brain tumors differ in histology, biology, prognosis and treatment options. Although structural magnetic resonance is still the gold standard for morphological tumor characterization, molecular imaging has gained an increasing importance in assessment of tumor activity and malignancy. RECENT FINDINGS Amino acid PET is frequently used for surgery and biopsy planning as well as therapy monitoring in suspected primary brain tumors as well as metastatic lesions, whereas 18F-fluorodeoxyglucose (18F-FDG) remains the tracer of choice for evaluation of patients with primary central nervous system lymphoma. Application of somatostatin receptor ligands has improved tumor delineation in skull base meningioma and concurrently opened up new treatment possibilities in recurrent or surgically not assessable tumors.Recent development focuses on the implementation of hybrid PET/MRI as well as on the development of new tracers targeting tumor hypoxia, enzymes involved in neoplastic metabolic pathways and the combination of PET tracers with therapeutic agents. SUMMARY Implementation of molecular imaging in the clinical routine continues to improve management in patients with brain tumors. However, more prospective large sample studies are needed to validate the additional informative value of PET.
Role of Arterial Compliance in the Physiopharmacological Approach to Human Hypertension

Arterial compliance in humans is generally measured by modeling analysis of pulse tracing or of pulse wave propagation in the arterial tree. It is decreased in hypertension in part because elevation of blood pressure stiffens the arteries by stretching the rigid collagen fibres of their walls. Using a modeling evaluation of the compliance-pressure relationship in large arteries, it is possible to correct compliance from the mechanical effect (passive effect) due to pressure elevation. This makes it possible to show that, at the same pressure as in normal controls, hypertensive patients maintain decreased arterial compliance. This finding suggests that functional and/or structural changes other than pressure-mediated stretching of arteries (active effect) contribute toward reducing arterial compliance. Thus, the response of compliance to antihypertensive drugs must be studied by differentiating between passive and active effects. The diameter and compliance-pressure relationship in arteries allow differentiation of a passive arterial effect due to the pressure-lowering action of the drug, and an active pharmacological effect calculated at the same pressure before and after drug administration. Four drugs–ketan-serin, urapidil, nitrendipine, and nicardipine (acute administration)–are given as examples. No active or passive compliance changes are observed with urapidil and ketanserin. In contrast, an active increase in compliance is observed in isobaric conditions with calcium antagonists, together with large-artery dilation due to a potent smooth muscle-relaxing effect. This active increase in compliance is potentiated by a passive increase due to the pressure-lowering effect that reduces the mechanical stretch exerted by blood pressure on arterial bioelasto-mers. Finally, an optimum increase in arterial compliance is achieved by drugs that vasodilate large arteries by smooth muscle relaxation and concomitantly decrease blood pressure. This may be of importance because low compliance has adverse effects on the cardiovascular system by contributing to the pathogenesis of systolic hypertension and left ventricular hypertrophy. Loss of arterial compliance may also be an early marker of atherosclerosis.
What lies behind compliance with operating leases disclosure?

ABSTRACT Compliance is one of the big challenges in the International Financial Reporting Standard (IFRS) implementation process. Additionally, the current debate on the operating leases accounting treatment is more in force than ever due to the recent support shown by the European Commission to companies lobbying against the proposal. In this article, we analyse and compare the level and evolution of compliance of UK and Spanish companies regarding mandated operating lease disclosures for the period of 2005–2011. Additionally, we look for determinants of compliance. Our results show a significant higher level of disclosure for UK compared with Spain and a positive trend in both countries towards full compliance. As for the determinants of compliance, media coverage and industry are found to be significant. The transparency needed in the markets demands high quality financial reporting and compliance commitment and, in this sense, we seem to be on the right track.