Miracle-dz/UniFAR-FTUs huggingface dataset:
Development, Testing of Construct Validity and Reliability of Pakistan Senior Citizens Quality of Life- Measurement Tool (PSCQL-MT)

This study has been dedicated to design, create and validate of quality of life (QoL) questionnaire called as (PSCQL-MT). This tool has been developed to measure physical activities, social relationship, cognitive aging, leisure activities and health behaviours. The objective of the study is to Develop, Test of Construct validity and reliability of (PSCQL-MT) to measure Quality of Life (QoL) in Senior Citizens of Lahore, Pakistan. Temporal stability was measured using the test-retest method. The overall questionnaire score shows an ICC of.86 (p <.001) with a 95% confidence interval (CI)=[. 83-. 89]. Analyses by dimensions range from a CCI of.72 (p <.001) with a 95% CI=[. 66-. 76] for the "other leisure activities" dimension to a CCI of.87 (p <.001) with a 95% CI=[. 84-. 89] for the "social activities" dimension. There was no specific valid questionnaire available in Pakistan to evaluate the individual and overall QoL in Pakistan. For this purpose, a reliable and valid construct questionnaire needs to be developed. This study has developed a tool that can measure 5 major variables which determine the QoL It has been concluded from the study that the development of PSCQL-MT questionnaire and valid tool is a great achievement to carry out research on the QoL in the study population.
Design of Minkowski Fractal Iteration in Monopole Patch Antenna

Many communication applications the antenna with smaller size, less weight and high efficiency is in demand. Monopole antenna able to process the wideband application and light weight. However, monopole antenna has the low return loss that affects the efficiency of the antenna. Fractal shapes has been applied in the monopole antenna to increase the return loss and efficiency. In this research, the Microstrip Minkowski Patch Antenna (MMPA) is proposed to increase the efficiency of monopole antenna. Minkowski Iteration Fractal antenna technique is applied to optimize the design in iterative manner for bandwidth and frequency tuning for wideband applications. The experimental evaluation shows that the proposed MMPA method has the higher bandwidth and more stable gain compared to the other fractal antennas. The return loss of the proposed MMPA’s second iteration is -21.38 dB at 3.2 GHz and base design has -30.37 dB at 3.6 GHz. Additionally, the MMPA is compared with existing Koch fractal antenna in terms of patch dimension and return loss. The patch dimension of the MMPA is 25×20 mm^2, it is less when compared to the Koch fractal antenna.
Modeling of the Fermentation Behavior of Starmerella bacillaris

Starmerella bacillaris has been proposed as a non-Saccharomyces species candidate to be used in mixed fermentations with Saccharomyces cerevisiae for the production of wine. Among the prospective applications, reductions in ethanol content and the acetic acid produced from high sugar musts have attracted particular attention. In this study, we described the fermentation behavior of six strains of S. bacillaris in grape must with initial sugar concentration ranging from 200 to 330 g/L. Time (days of fermentation) was a second variable that was monitored for its influence on fermentation. Response surface methodology was employed to model the behavior of the strains. The six strains generally behaved uniformly. Residual sugar concentration and production of ethanol, glycerol, and acetic acid mainly depended on time. Initial sugar concentration in the must was positively associated with residual glucose in musts with higher initial sugar concentration. Similarly, malic acid consumption showed a dependence on time and sugar concentration and was inhibited in musts with a higher sugar content. The behavior of S. bacillaris strains can be considered compatible with enological practices that may involve mixed fermentation with S. cerevisiae.
A Study on BOE’s Private Placement Risk and the Tunneling Behavior of Stakeholders

The issue of private placement risks and tunneling behavior associated with Chinese enterprise stakeholders is a matter of greater concern in academic and industry. On the basis of Agency Theory and Asymmetric Information Theory, the study adopts the case-study method—taking BOE(Beijing Over East) to investigate the refinancing risk and tunneling behavior in 2014. The BOE case is a very typical case in the field of a private placement of Chinese companies. The findings indicate that the risk from private placement varies among different types of stakeholders (large stockholders, minority stockholders, new investors, management, etc.). Also, the tunneling behavior mainly manifests as earnings management, private placement pricing, subscription method, management subscription, and so on. Suggestions for this study are as follows: First, choose a financing and development mode that fits the company, maintain steady funding sources, and set a high-quality offering target. Second, respond by consolidating the company's strengths and improve its all-around abilities, such as innovation, competitiveness, and profit capability. Third, choose the right timing to issue the private placement. Fourth, take every opportunity to improve the confidence of the market and the related investors.
Mechanism of resistance to tyrosine kinase inhibitors - A case report and review

This report aims to assess the viability of various challenging approaches such as tyrosine kinase inhibitors (TKIs) therapy, chemotherapy, and stem cell transplantation in patients with chronic myeloid leukemia (CML), especially for those in an advanced phase. Although standard treatments have been extremely effective in combating CML propagation and negating the disease symptoms along with an increased survival rate, these traditional treatment methods have experienced an increased failure rate due to TKI treatment resistance. A common mechanism that can be attributed to the increase in TKI resistance is the increasing mutations of the BCR-ABL 1 kinase domain. These mutations can be clearly observed in clinical trials. Currently, there are five BCR-ABL 1 kinase inhibitors that are approved for the safe treatment of CML. These are imatinib, dasatinib, nilotinib, bosutinib, and ponatinib. Mutational testing should be carried out on patients in such cases that show little response to traditional TKI therapy.In this report, we evaluate a patient who has been diagnosed with an accelerated phase CML and requires constant monitoring to tailor the treatment program to their requirements.
Effects of salvianolate on myocardial perfusion after primary percutaneous catheter intervention in patients with ST-segment elevation myocardial infarction: a multicenter, randomized, double-blind, placebo-controlled study

Background Despite prompt revascularization following acute myocardial infarction, poor myocardial perfusion commonly occurs due to impaired microvascular circulation and is an independent predictor of adverse outcomes. The current trial sought to examine the effects of salvianolate on myocardial perfusion in patients with ST-segment-elevation myocardial infarction (STEMI) who were undergoing primary percutaneous coronary intervention (PCI). Methods This randomized, double-blind, placebo-controlled, multicenter study evaluated the effects of intravenous salvianolate on the achievement of complete epicardial and myocardial reperfusion after PCI, defined as thrombolysis in myocardial infarction flow grade 3 and thrombolysis in myocardial infarction myocardial perfusion grade 3. We also measured plasma total creatine kinase-mass band fraction (CK-MB)-estimated infarct size and echocardiography-derived left ventricular ejection fraction and recorded the 30-day clinical and safety outcomes. A total of 536 patients presenting with acute STEMI were randomized to receive either an i.v. infusion of salvianolate (n=265) or placebo (n=271). Results Salvianolate administration exerted beneficial effects on coronary microcirculation. There was a trend of reduced myocardial infarct size in the salvianolate group compared to the placebo group (P=0.070), although no significant difference in left ventricular ejection fraction was found between the two groups. Conclusions Salvianolate administration is associated with improved myocardial perfusion in patients with STEMI undergoing PCI. A larger study is required to assess the impact of this therapy on clinical cardiac outcomes.
Non-Linear 3d Reconstruction For Compressive X-Ray Tomosynthesis

Compressive X-ray tomosynthesis is an emerging technology that can be used for medical diagnosis, safety inspection and industrial non-destructive testing. Traditional compressive X-ray tomosynthesis uses sequential illumination to interrogate the object of interest, which generates non-overlapping projection measurements. However, when multiple X-ray sources emit simultaneously, the projections corresponding to different sources overlap creating multiplexed measurements. Such measurement strategy leads to a non-linear reconstruction problem. The reconstruction of the three-dimensional (3D) object from multiplexed projections is an important problem. This paper proposes a non-linear 3D reconstruction approach for compressive X-ray tomosynthesis, where a set of coding masks are used to generate structured illumination and reduce radiation dose. The effectiveness of the method is verified by simulation experiments. It is shown that the proposed approach can reconstruct high-quality images with just a few snapshots.
Effect of four intestinal strains on TNF-a ÃÂ± IL8 and IL6 expression in Caco-2 cells

Gut microbiota play an important roles in induction of various cellular responses, including cytokine production. In this work, we examined the involvement of four intestinal strains in induction of the cytokine response (the relative expression of TNF-α, IL-6, and IL-8) in intestinal epithelial cells. Caco-2 cells were treated with cell-free supernatants (CFS) of four intestinal strains: Shigella spp. , Bacteroides fragilis, Weissella cibaria, Enterococcus faecium. Shigella spp. , Bacteroides fragilis, Weissella cibaria, Enterococcus faecium CFSs resulted in marked an increase of mRNA TNF-α content ( p<0.05 or p<0.01). In additon, Shigella spp. CFS, Bacteroides fragilis CFS, Weissella cibaria CFS significantly increased expression mRNA for IL-8 ( p<0.05 or p<0.01), In contrast, Enterococcus faecium caused significant a decrease of mRNA IL-8(p<0.01). Last but not the least important, Shigella spp. , Bacteroides fragilis, Weissella cibaria, Enterococcus faecium CFSs led to mark an increase of mRNA IL-6 level (p<0.01). These results indicate that four intestinal strains produce bioactive metabolites, suggesting that gut microbiota metabolites may therefore provide an entirely new approach towards protection of intestinal epithelial and treatment of human diseases.
A System for Quality Assessment of Forestry Contractors

Skilled contractors are needed to meet the increased demand for wood and to maintain a competitive edge in forestry. The structure of the forest industry has changed significantly. Today’s situation favours smaller contractors that are more flexible. Worldwide contractors are important for forest operations, but there is often limited knowledge about how well they fulfil demands about resource efficiency, social responsibility and environmental protection. The aim of this paper is to present the guidelines for the assessment of forestry contractors following sustainability principles and to present a recently developed system. In addition to the requirements for professional competences and legislative obligations, the system proposes a number of additional requirements such as corporate social responsibility, participation in the local community and greater environmental responsibility. The forestry contractor and the certification body sign a cooperation agreement to obtain the expert assessment. The expert assessment is performed by an evaluator authorised by a certification body. A web service has been introduced with the purpose of serving as a communication tool between professional evaluators and forestry contractors, as well as providing a new possibility for forest owners to get direct contact with forestry contractors. The system enables its users to exert influence on the assessment of forestry contractors by assessing the quality of their services. Private forests would greatly benefit from customer feedback information on the service quality. By now, 1584 forest contractors have registered in Slovenia, where 67% provide the service of cutting and skidding, 8% provide woodchipper service, 7% transport of round wood, 5% cable crane yarding and 4% fully mechanised harvesting. Until June 2020, 142 forest contractors have gone through the process of quality assessment.
Bioprocessing of Moisturized Cereals: Ruminants Crave

The objective of this article was to practically elaborate on bioprocessing of moisturized whole and wheat grains by rumen microbes and the host ruminant. Moisturizing is a feasible cost-effective biprocessing approach towards optimizing cereal grains utilization in rumen, post-rumen gut, splanchnic tissues, and the ruminant periphery. However, despite the recent emphases on optimizing cereal use by ruminants [1-4], inadequate practical information exists to highlight the pragmatic influence of moisturizing cereals on rumen function and ruminant health and productivity.
A Stochastic View of the 2020 Elazığ Mw 6.8 Earthquake (Turkey)

Until the Mw 6.8 Elazığ earthquake ruptured the central portion of the East Anatolian Fault (EAF, Turkey) on January 24, 2020, the region had only experienced moderate magnitude (Mw < 6.2) earthquakes over the last century. We use geodetic data to constrain a model of subsurface fault slip. We adopt an unregularized Bayesian sampling approach relying solely on physically justifiable prior information and account for uncertainties in both the assumed elastic structure and fault geometry. The rupture of the Elazığ earthquake was mostly unilateral, with two primary disconnected regions of slip. This rupture pattern may be controlled by structural complexity. Both the Elazığ and 2010 Mw 6.1 Kovancılar events ruptured portions of the central EAF that are believed to be coupled during interseismic periods, and the Palu segment is the last portion of the EAF showing a large fault slip deficit which has not yet ruptured in the last 145 years.
A Dynamic Model of Information and Entropy

We discuss the possibility of a relativistic relationship between information and entropy, closely analogous to the classical Maxwell electro-magnetic wave equations. Inherent to the analysis is the description of information as residing in points of non-analyticity; yet ultimately also exhibiting a distributed characteristic: additionally analogous, therefore, to the wave-particle duality of light. At cosmological scales our vector differential equations predict conservation of information in black holes, whereas regular- and Z-DNA molecules correspond to helical solutions at microscopic levels. We further propose that regular- and Z-DNA are equivalent to the alternative words chosen from an alphabet to maintain the equilibrium of an information transmission system.
An e-Learning Toolbox Based on Rule-Based Fuzzy Approaches

In this paper, an e-Learning toolbox based on a set of fuzzy logic data mining techniques is presented. The toolbox is mainly based on the fuzzy inductive reasoning (FIR) methodology and two of its key extensions: (i) the linguistic rules extraction algorithm (LR-FIR), which extracts comprehensible and consistent sets of rules describing students’ learning behavior, and (ii) the causal relevance approach (CR-FIR), which allows to reduce uncertainty during a student’s performance prediction stage, and provides a relative weighting of the features involved in the evaluation process. In addition, the presented toolbox enables, in an incremental way, detecting and grouping students with respect to their learning behavior, with the main goal to timely detect failing students, and properly provide them with suitable and actionable feedback. The proposed toolbox has been applied to two different datasets gathered from two courses at the Latin American Institute for Educational Communication virtual campus. The introductory and didactic planning courses were analyzed using the proposed toolbox. The results obtained by the functionalities offered by the platform allow teachers to make decisions and carry out improvement actions in the current course, i.e., to monitor specific student clusters, to analyze possible changes in the different evaluable activities, or to reduce (to some extent) teacher workload.
Printed planar tunable composite right/left‐handed leaky‐wave antenna based on a tunable polymer‐BST substrate

This article presents a printed tunable right/left‐handed leaky wave antenna (LWA) on a new flexible, tunable low density polyethylene‐barium strontium titanate composite substrate using an aerosol jet printer. The new substrate had a dielectric constant of 16 and tunability of 3.5% at f = 10 GHz. Interdigital capacitors (IDC) were utilized in the leaky wave antenna design not only to act as shunt capacitor in CRLH transmission line design but also as tunability element to implement tuning capability of the LDPE‐BST substrate for antenna beam steerability for a fixed operated frequency in X‐band frequency range. Up to 15° beam steering was achieved by applying DC voltage through the printed leaky wave antenna.
Optimizing Redox Reactions in Aprotic Lithium–Sulfur Batteries

The lithium–sulfur battery is regarded as one of the promising energy‐storage devices beyond lithium‐ion battery due to its overwhelming energy density. The aprotic Li–S electrochemistry is hampered by issues arising from the complex solid–liquid–solid conversion process. Recently, tremendous efforts have been made to optimize the electrochemical reaction in Li–S batteries through rationally designing compositions and structures of cathodes. However, a deep and comprehensive understanding of the actual mechanisms of Li–S batteries and their impact on the performance is still insufficient. The vigorous development of various electrochemical analysis and in situ techniques establish a bridge between the microstructure of components and the macroscopic electrochemical performance, thus providing more scientific guidance for the optimal design of Li–S batteries. In this review, based on insights into the mechanism of aprotic Li–S electrochemistry with the aid of in situ characterization and electrochemical methods, the advanced innovations in optimizing Li–S batteries are systematically summarized, including the materials design, cathode configurations optimization, and electrolyte engineering, with the aim to gain a comprehensive understanding of cathodic redox processes and thus achieve high‐performance Li–S batteries. The current status and possible future directions of the field are accordingly outlined.
Prevalence of Helicobacter pylori virulence genes among Iranian infected patients: a systematic review and meta-analysis

Introduction: Helicobacter pylori infection as the worldwide problem is related to many gastrointestinal disorders. Because of antithesis results among different articles; we systematically reviewed articles about the prevalence of H. pylori virulence factors among different diseases (gastritis, gastric cancer, nonulcer disease, peptic ulcer disease, duodenal ulcer) in different regions of Iran. Methods: We used the Preferred Reporting Items for Systematic Review and Meta-Analysis statement for reporting systematic review and meta-analysis of this study in national and international databases. We searched the cagA, vacA, oipA, babA, iceA, dupA prevalence among infected patients in Iran. We used Newcastle--Ottawa quality for assessing the quality of studies in meta-analyses. Due to significant heterogeneity of the results, random effects model to calculate pooled prevalence estimates with 95% confidence intervals, weighted by study size. Results: Among 1106 reports screened, 28 related articles were eligible for meta-analysis. The pooled prevalence (95% confidence interval) of cagA, vacA, oipA, babA, iceA1, iceA2, dupA were estimated as 62% (21--95), 71.2% (38–82), 71% (13–99), 61.6% (3–96), 36.2% (12–90), 26.2% (13–37), 40.8% (12–55), respectively. Discussion: The frequency of virulence factor genes among H. pylori strains isolated in Iranian patients to be more frequently associated with the gastrointestinal disease compared with the other countries and these data can be considered in development of eradication strategies.
Nitrogen-induced terrestrial eutrophication: cascading effects and impacts on ecosystem services

Human activity has significantly increased the deposition of nitrogen (N) on terrestrial ecosystems over pre-industrial levels leading to a multitude of effects including losses of biodiversity, changes in ecosystem functioning, and impacts on human well-being. It is challenging to explicitly link the level of deposition on an ecosystem to the cascade of ecological effects triggered and ecosystem services affected, because of the multitude of possible pathways in the N cascade. To address this challenge, we report on the activities of an expert workshop to synthesize information on N-induced terrestrial eutrophication from the published literature and to link critical load exceedances with human beneficiaries by using the STressor–Ecological Production function–final ecosystem Services Framework and the Final Ecosystem Goods and Services Classification System (FEGS-CS). We found 21 N critical loads were triggered by N deposition (ranging from 2 to 39 kg N·ha−1·yr−1), which cascaded to distinct beneficiary types through 582 individual pathways in the five ecoregions examined (Eastern Temperate Forests, Marine West Coast Forests, Northwestern Forested Mountains, North American Deserts, Mediterranean California). These exceedances ultimately affected 66 FEGS across a range of final ecosystem service categories (21 categories, e.g., changes in timber production, fire regimes, and native plant and animal communities) and 198 regional human beneficiaries of different types. Several different biological indicators were triggered in different ecosystems, including grasses and/or forbs (33% of all pathways), mycorrhizal communities (22%), tree species (21%), and lichen biodiversity (11%). Ecoregions with higher deposition rates for longer periods tended to have more numerous and varied ecological impacts (e.g., Eastern Temperate Forests, eight biological indicators) as opposed to other ecoregions (e.g., North American Deserts and Marine West Coast Forests each with one biological indicator). Nonetheless, although ecoregions differed by ecological effects from terrestrial eutrophication, the number of FEGS and beneficiaries impacted was similar across ecoregions. We found that terrestrial eutrophication affected all ecosystems examined, demonstrating the widespread nature of terrestrial eutrophication nationally. These results highlight which people and ecosystems are most affected according to present knowledge, and identify key uncertainties and knowledge gaps to be filled by future research.