Miracle-dz/UniFAR-FTUs huggingface dataset:
Smart Discovery of Cultural and Natural Tourist Routes

This paper presents a system designed to utilize innovative spatial interconnection technologies for sites and events of environmental, cultural and tourist interests. The system will discover and consolidate semantic information from multiple sources, providing the end-user the ability to organize and implement integrated and enhanced tours. The system, called e-xnilatis, will extend existing innovative techniques, including: semi-automated searching and extraction of real-time knowledge from online resources, automated discovery of points of interest as well as events, semantic integration, classification and hierarchy of information from various sources, spatial representation of content, personalized user experience and Augmented Reality (AR) for the interconnection of the digital with the natural environment. A complex online platform and applications for smart devices will be developed so that the user manages and receives the optimum route information along with AR experience when applicable. The platform will be an open architecture tool that, with the appropriate time-space constraints, will be able to create adaptive content. A typical example of this is the Egnatia motorway, where the e-xnilatis platform will be evaluated.
FPGA-Accelerated Optimistic Concurrency Control for Transactional Memory

Transactional Memory (TM) has been considered as a promising alternative to existing synchronization operations, which are often the largest stumbling block to unleashing parallelism of applications. Efficient implementations of TM, however, are challenging due to the tension between lowering performance overhead and avoiding unnecessary aborts. In this paper, we present Reachability-based Optimistic Concurrency Control for Transactional Memory (ROCoCoTM), a novel scheme which offloads concurrency control (CC) algorithms, the central building blocks of TM systems, to reconfigurable hardware. To reduce the abort rate, an innovative formalization of mainstream CC algorithms is developed to reveal a common restriction that leads to unnecessary aborts. This restriction is resolved by the ROCoCo algorithm with a centralized validation phase, which can be efficiently pipelined in hardware. Thanks to a high-performance offloading engine implemented in reconfigurable hardware, ROCoCo algorithm results in decreased abort rates and reduced performance overhead. The whole system is implemented on Intel's HARP2 platform and evaluated with the STAMP benchmark suite. Experiments show 1.55x and 8.05x geomean speedup over TinySTM and an HTM based on Intel TSX, respectively. Given the fast-growing deployment of commodity CPU-FPGA platforms, ROCoCoTM paves the way for software programmers to exploit heterogeneous computing resources with a high-level transactional abstraction to effectively extract the parallelism in modern applications.
Detection of suspicious time windows in memory monitoring

Modern memory monitoring tools do not only offer analyses at a single point in time, but also offer features to analyze the memory evolution over time. These features provide more detailed insights into an application's behavior, yet they also make the tools more complex and harder to use. Analyses over time are typically performed on certain time windows within which the application behaves abnormally. Such suspicious time windows first have to be detected by the users, which is a non-trivial task, especially for novice users that have no experience in memory monitoring. In this paper, we present algorithms to automatically detect suspicious time windows that exhibit (1) continuous memory growth, (2) high GC utilization, or (3) high memory churn. For each of these problems we also discuss its root causes and implications. To show the feasibility of our detection techniques, we integrated them into AntTracks, a memory monitoring tool developed by us. Throughout the paper, we present their usage on various problems and real-world applications.
DCMI

Iterative Stencil Loops (ISLs) are the key kernel within a range of compute-intensive applications. To accelerate ISLs with Field Programmable Gate Arrays, it is critical to exploit parallelism (1) among elements within the same iteration and (2) across loop iterations. We propose a novel ISL acceleration scheme called Direct Computation of Multiple Iterations (DCMI) that improves upon prior work by pre-computing the effective stencil coefficients after a number of iterations at design time—resulting in accelerators that use minimal on-chip memory and avoid redundant computation. This enables DCMI to improve throughput by up to 7.7× compared to the state-of-the-art cone-based architecture.
From definitional interpreter to symbolic executor

Symbolic execution is a technique for automatic software validation and verification. New symbolic executors regularly appear for both existing and new languages and such symbolic executors are generally manually (re)implemented each time we want to support a new language. We propose to automatically generate symbolic executors from language definitions, and present a technique for mechanically (but as yet, manually) deriving a symbolic executor from a definitional interpreter. The idea is that language designers define their language as a monadic definitional interpreter, where the monad of the interpreter defines the meaning of branch points. Developing a symbolic executor for a language is a matter of changing the monadic interpretation of branch points. In this paper, we illustrate the technique on a language with recursive functions and pattern matching, and use the derived symbolic executor to automatically generate test cases for definitional interpreters implemented in our defined language.
Exploiting Social Media to enhance Clinical Decision Support

Social media are increasingly used to collect data and report on the personal health status, on health issues, symptoms and experiences with treatments. The health data that is, thus, becoming available represents a valuable source for continuous health monitoring and prevention, and clinical decision making. Detecting diseases at early stage can help to overcome and treat them accurately. Social media data can be used to understand, in near real time, human life dynamics worldwide. These massive quantities of data could support in a wide range of medical and healthcare applications, including among others clinical trials and decision support. A Clinical Decision Support System (CDS) can greatly help in identifying diseases and methods of treatment. In this paper we propose a CDS framework that can integrate heterogeneous health data from different sources, such as laboratory test results, basic information of patients, health records and social media data. Using the electronic health medical data so collected, innovative machine learning and deep learning approaches are employed to implement a set of services to recommend a list of diseases and thus assist physicians in diagnosing or treating their patients’ health issues more efficiently.
Optimizing Energy Efficiency of Browsers in Energy-Aware Scheduling-enabled Mobile Devices

Web browsing, previously optimized for the desktop environment, is being fine-tuned for energy-efficient use on mobile devices. Although active attempts have been made to reduce energy consumption, the advent of energy-aware scheduling (EAS) integrated in the recent devices suggests the possibility of a new approach for optimizing energy use by browsers. Our preliminary analysis showed that the existing EAS-enabled system is overly optimized for performance, leading to energy inefficiencies while a web browser is running. In this paper, we analyze the characteristics of web browsers, and investigate the cause of energy inefficiency in EAS-enabled mobile devices. We then propose a system, called WebTune, to improve the energy efficiency of mobile browsers. Exploiting the reinforcement learning technique, WebTune learns the optimal execution speed of the web browser's processes, and adjusts the speed at runtime, thus saving energy and ensuring the quality of service (QoS). WebTune is implemented on the latest Android-based smartphones, and evaluated with Alexa's top 200 websites. The experimental results show that WebTune reduced the device-level energy consumption of the Google Pixel 2 XL and Samsung Galaxy S9 Plus smartphones by 18.7-22.0% and 13.7-16.1%, respectively, without degrading the QoS.
Sífilis gestacional y factores asociados en hospitales públicos del Perú en el periodo 2000-2010

Objetivos. Determinar el perfil epidemiologico de la sifilis gestacional y factores asociados en una poblacion peruana. Materiales y metodos. El estudio es un analisis secundario de datos obtenidos de hospitales publicos del Peru para el periodo 2000-2010. Se incluyo datos de 652 636 gestantes de 37 ciudades y de 45 establecimientos de salud del Peru. Resultados. Se estimo la prevalencia de sifilis gestacional en 0,7% y de tamizaje de sifilis materna en 80,7%. La mayor prevalencia de sifilis materna se encontro en la selva baja seguida de la selva alta. En las tres regiones del Peru se aprecia una disminucion de la prevalencia de sifilis gestacional en el transcurso de los anos. Las prevalencias al 2010 son de 0,2% en la costa, 0,23% en la sierra y 0,47% en la selva. La ausencia de educacion, el bajo numero de control prenatal, la mayor paridad, el ser conviviente o soltera, y el vivir en la selva, son factores asociados a la positividad en la prueba de sifilis. Conclusiones. Los resultados sugieren que la prevalencia de sifilis gestacional ha presentado una tendencia decreciente durante la decada 2000-2010
Sulfasalazine: Potential use of an old drug for treatment of pancreatic cancer

4705 Pancreatic cancer is one of the most aggressive and therapy-resistant cancers known. Although chemotherapy using gemcitabine has yielded increases in patient survival, there is no effective therapy for this disease. We have previously found that sulfasalazine (SASP), an established anti-inflammatory drug, can arrest proliferation of lymphoma and prostate cancer cells both in vitro at patient-tolerated levels (∼0.2 mM) and in experimental animals. The in vitro action of SASP is largely based on inhibition of cystine uptake via the xc- cystine/glutamate antiporter. This amino acid, essential for cell growth and viability, cannot be synthesized by certain cancers, rendering them dependent on its uptake from their environment. In the present study we investigated the potential usefulness of SASP for therapy of pancreatic cancer. Human pancreatic cancer cell lines, Mia PaCa-2, Panc-1 and Bxpc-3, were incubated with SASP at a range of concentrations for various periods and cell numbers determined via the WST-1 cell proliferation assay. RT-PCR was used to determine mRNA expression of the xCT subunit of the xc- cystine transporter. In vivo activity of SASP was evaluated using Rag-2M mice carrying subrenal capsule xenografts of the cancer cells (about 80 mm3). I.p. injections of saline or SASP (250 mg/kg body weight) were administered every 12 h for 7 days; the effect of gemcitabine (120 mg/kg body weight; i.p.), twice a week for 7 days, was also assessed. Animals were then sacrificed and tumors harvested for volume measurement and histological analysis. In vitro, Mia PaCa-2 and Panc-1 cells were particularly sensitive to growth inhibition and lytic action by SASP (IC50 = 0.05 mM and 0.1 mM, respectively); the inhibition could be prevented by 60 μM 2-mercaptoethanol allowing cystine uptake via the leucine transporter. The Bxpc-3 cells were less sensitive to SASP (IC50 = 0.35 mM), showing increased expression of xc-, as indicated by elevated xCT-mRNA levels. In vivo, both SASP and gemcitabine inhibited growth of xenografts of the three cell lines, showing growth arrest of about 40-60% (relative to controls), without major toxicity to the hosts. While the growth-inhibitory effect of SASP on pancreatic cancer cell proliferation in vitro involves cystine starvation, the anticancer activity of SASP in vivo needs further investigation. Nevertheless, the marked anti-tumor activity of SASP without major toxicity to the hosts suggests that this established drug could be useful in combination chemotherapy of pancreatic cancer. Supported by the Canadian Institutes of Health Research (PWG/YZW).
High resolution ECG, heart rate variability and nonlinear dynamics: tools for high risk stratification

With traditional methods one can detect only 30-40% of patients threatened by sudden cardiac death. Therefore the authors intend to investigate and apply new methods of nonlinear dynamics to improve the detection rate of high risk patients. First results of an initial investigation show, that these new methods could lead to a new classification of high risk patients. The detected abnormalities suggest a high risk in several patients who have been classified in the low risk group by traditional analysis. <<ETX>>
Mass Screening is Inevitable to Detect the Curable Early Stage Prostate Cancer

Objective To investigate the influence of the mass screening on the status of the prostate cancer (PCa), we compared the cases of PCa detected by the mass screening and the cases diagnosed at a conventional ordinary urologic outpatient. Methods Using a SPSS analysis system, We compared 67 cases of prostate cancer detected by mass screening and 358 cases diagnosed at the outpatient of various hospitals in Changchun in terms of age distribution, clinical stages, level of serum prostate special antigen (PSA), pathological stage and treatment modality. Results The annual average incidence of PCa during 1999 to 2001 increased 4.72 times when compared to the 1986 to 1989's. In the screening group, the cases with clinical stage T2 and T1 accounted for 59.7%. In the clinical group, it was only 28.0%, and mostly detected incidentally. Furthermore, in the screening group the percentage of the cases beyond 20 ng/ml PSA and of poorly differentiated carcinoma were much lower compared to the clinical group. These differences between them were statistically significant. The number of radical prostatectomy in the screening group increased 15.3% compared with that of the clinical group. Conclusion Only the mass screening can really reveal the actual prevalence of prostate cancer. It can markedly raise the number of prostate cancer, especially the cancer in the early stage.
Recognising women’s responses to heart disease symptoms: different groups respond in different ways

ii ACKNOWLEDGEMENTS. iv DEDICATION. vi TABLE OF CONTENTS. vii LIST OF TABLES. xiv LIST OF FIGURES . xv LIST OF ABBREVIATIONS. xvi PROLOGUE . xvii CHAPTER I: INTRODUCTION. 1 Overview. 1 Preamble . 1 Aims and objectives of the study . 5 Objectives . 5 Thesis Structure . 6 Summary . 10 CHAPTER II: LITERATURE REVIEW . 11 WOMEN AND HEART DISEASE. 11 Overview. 1
Influence of Clinical and Pathologic Parameters on Prognosis of Cervical Carcinoma in China

Objective: To explore the influence of clinical and pathologic parameters on the prognosis of squamous cell carcinoma and adenocarcinoma. Methods: 702 cases of cervical carcinoma were retrospec-tively studied. Cox regression model was informed in multi-variable analysis. Results: The retrospective analysis showed that 630 out of 702 cases of cervical carcinoma were squamous cell carcinoma, cumulative rate 89.4% and 72 case were adenocarcinoma, cumulative rate 10.6% respectively. The 5-year survival rate was lower for patients with adenocarcinoma than for patients with squamous cell carcinoma (58.3% vs 57.3%), but there was no significant difference. Cox regression model showed that the variable into equation for squamous cell carcinoma included tumor grade of differentiation, lymph node metastasis and FIGO stage, but only lymph node metastasis and FIGO stage for adenocarcinoma. Conclusion: FIGO stage and lymph node metastasis was independent parameter evaluating prognosis of cervical carcinoma.
Communication in Trauma Teams: Occurrence of CRM markers in patient simulator training

Trauma is a leading cause of death. There is a great need for training of human factors such as communication and teamwork in trauma teams. The use of simulation in medical education is increasing, and together with learning strategies based on experiential learning theory, it can be a powerful tool in team training. The aviation-based concept of crew resource management, CRM, in which framework communication is a key component, can be applied also in the health care domain. The aim of the study was to investigate if change of communication is observable in trauma teams in CRM training and further to see if results are relevant for course development and patient safety improvement. The setting is a simulation centre at a university hospital in Sweden. Three trauma teams were filmed during training and incidence and variation of chosen communication markers studied. Results suggest that communication changes within teams and that different change is observable in different teams. In an experiential learning perspective this indicates that the trauma team training in question should be developed further. In a patient safety perspective results indicate, together with other studies, that the hospital should integrate simulation training in a comprehensive patient safety programme.
Injury patterns of South African provincial cricket players over two seasons

Objective. To determine the incidence and nature of injury patterns in elite cricketers over two seasons. Methods. Physiotherapists and/or doctors working with 4 provincial teams completed a questionnaire for each cricketer who presented with an injury during the 2004 - 2005 (S1) and 2005 - 2006 (S2) cricket seasons. This was done to determine: (i) the anatomical site of injury; (ii) the month of injury during the season; (iii) the diagnosis using the OSCIS injury classification system; (iv) the mechanism of injury; (v) whether it was a recurrence of a previous injury; (vi) whether the injury had recurred again during the season; and (vii) biographical data. Results. The results showed that 180 injuries (S1 – 84; S2 – 96) were sustained. On average the teams spent 2 472 hours on matches, 4 148 on practices and 1 612 on fitness training during the two-season period. The injury prevalence was 8% per match, while the injury incidence was 30/10 000 hours of match, practice and training time, with the match incidence being 74 injuries/ 10 000 hours and the training incidence 15 injuries/10 000 hours. Bowling (29%), fielding and wicket-keeping (27%) and batting (19%) accounted for the majority of injuries. The occurrence of injuries was predominantly to the lower limbs (S1 – 45%; S2 – 42%), back and trunk (S1 – 19%; S2 – 19%), upper limbs (S1 – 19%; S2 – 22%), head and neck (S1 – 6%; S2 – 3%), and related to illnesses (S1 – 11%; S2 – 14%). The injuries occurred primarily during first-class matches (39%), limited-overs matches (22%), and practices (17%), and some were of gradual onset (20%). Acute injuries comprised 78% of injuries. The majority of injuries were first-time injuries (76%), with 11% and 14% recurrent injuries from the previous and current seasons, respectively. The major injuries during S1 were haematomas (19%), muscle strains (17%) and other trauma (14%), while during S2 the injuries were primarily muscle strains (16%), other trauma (20%), tendinopathy (16%) and acute sprains (15%). The primary mechanisms of injury occurred in the delivery stride when bowling (19%) and overbowling (7%), on impact by the ball when batting (11%), and on sliding to field the ball (6%). Conclusion. The results indicate a pattern of cause of injury, with the fast bowler most likely to sustain an acute injury to the soft tissues of the lower limb while participating in matches and practices during the early part of the season.
Nutrition and Heart Disease: Causation and Prevention

DIETS AND HEART DISEASE PREVENTION The Role of the Dietitian in reducing cardiovascular risk: an evidence based approach, Hooper Seafood and Myocardial Infarction in China, Yuan The Low Occurrence of Coronary Heart Disease in Sub-Saharan African Populations, Walker Dietary Prevention of Coronary Heart Disease, de Lorgeril , P.Salen Effects of Nutritional Education on Cardiovasular Risk Factors, Bemelmans NUTRIENTS AND HEART DISEASE Micronutrients and Cardiovascular Disease, Witte, Clark Leptin and Blood Pressure, Swoap, Overton Retinol, Beta-Carotene, and alpha tocopherol in Heart Disease, Lopes, Casal, Oliveira, Barros Folate, Homocysteine, and Heart Disease, Ashfield-Watt, Burr, McDowell FOODS AND MACRONUTRIENTS IN HEART DISEASE Flavonoids (also known as Bioflavonoids), Extracted and in Foods: Role in Hypertention Prevention and Treatment, Mlakar, Simpson High Carbohydrate Diets and Lipids Metabolism, Beylot Vasculoprotective Effects of Olive Oil: Epidemiological Background and Direct Vascular Antiatherogenic Properties, Massaro, Scoditti Cardiovascular Effects of Dietary Soy, Clarkson. Appt Malnutrition and the Heart: A Pediatric Perspective, Venugopalan Plant Sterols and Plant Stanols, lipoprotein metalbolism, and cardiovascular disease, Naumann, Plat, Mensink Non-Nutrient Food Factors and Cardiovascular Diseases, S. Vaghefi AGE AND HEART DISEASE Age Related Cardiac Dysfunction, Yang, Larson, Watson Inducible Nitric Oxide Synthase (iNOS) and Heart Failure, Yang, Larson, Watson
Management of ankylosed young permanent incisors after trauma and prior to implant rehabilitation

The objective of this clinical report is to present decoronation of young permanent ankylosed incisors as an option to preserve the alveolar process in young people where implant rehabilitation is not yet indicated. A 13-year-old patient presented with intrusive luxation of the permanent maxillary lateral incisor and lateral luxation of both permanent maxillary central incisors. During 6 months, clinical and radiographic evaluation showed progressive root replacement resorption, and surgical decoronation was recommended for all three incisors and left for a period of 6 years until the implant and grafting procedures be performed. Decoronation in young teeth is a reliable technique in terms of preservation of the width and height of the alveolar process, and improves the aesthetic conditions after installation of the provisional prosthetics. Decoronation may be considered an alternative strategy for complex posttraumatic clinical scenarios, such as young ankylosed incisors.