Miracle-dz/UniFAR-FTUs huggingface dataset:
FRI0498 HIGH SERUM URIC ACID LEVEL IS ASSOCIATED WITH LOWER INCIDENCE OF OSTEOPOROSIS IN POSTMENOPAUSAL WOMEN: DATA FROM THE KOREAN NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY

Background Osteoporosis is one of the most common morbidities in postmenopausal women. Although serum uric acid (SUA) accounts for about 50% of extracellular antioxidant activity, the role of hyperuricemia in osteoporosis, a condition characterized by high oxidative stress level, has not been investigated in a Nation-wide scale. Objectives The aim of this study is to evaluate an association between SUA and incidence of osteoporosis in postmenopausal women. Methods Data of postmenopausal women from the 2016 Korean National Health and Nutrition Examination Survey were included and retrospectively analyzed. Weighted prevalence and logistic regression analysis were used to determine the incidence of osteoporosis and the effect of SUA on osteoporosis in postmenopausal women. Results One-thousand three-hundred eighty-two (weighted n = 7,064,137) of postmenopausal women were observed. Of these, 401 (29.0%, weighted n = 1,880,586) women developed osteoporosis. Mean age of participants was 63.2 years and mean of SUA was 4.4 mg/dL. The effect of SUA on osteoporosis in postmepausal women was not statistically significant according to univariable logistic regression (OR 0.977, 95% CI 0.855-1.116, p = 0.729). However, SUA was negatively associated with incidence of osteoporosis in postmenopausal women with statistical significance after adjusting for age, obesity, amount of drink, smoking, intake of calcium, rheumatoid arthritis, thyroid diseases, and loss of activity (OR 0.867, 95% CI 0.752-0.999, p = 0.048). Conclusion Our data demonstrated that high SUA is associated with lower incidence of osteoporosis in postmenopausal women. This result suggests a protective role of SUA in metabolic bone diseases. References [1] Hernlund E, Svedbom A, Ivergard M, Compston J, Cooper C, Stenmark J, et al. Osteoporosis in the European Union: medical management, epidemiology and economic burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos. 2013;8:136. [2] Varacallo MA, Fox EJ. Osteoporosis and its complications. Med Clin North Am. 2014;98(4):817-31. [3] Wauquier F, Leotoing L, Coxam V, Guicheux J, Wittrant Y. Oxidative stress in bone remodelling and disease. Trends Mol Med. 2009;15(10):468-77. [4] Lee NK, Choi YG, Baik JY, Han SY, Jeong DW, Bae YS, et al. A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation. Blood. 2005;106(3):852-9. [5] Bai XC, Lu D, Liu AL, Zhang ZM, Li XM, Zou ZP, et al. Reactive oxygen species stimulates receptor activator of NF-kappaB ligand expression in osteoblast. J Biol Chem. 2005;280(17):17497-506. Disclosure of Interests None declared
3D Direct Manipulation Interface by Human Body Posture and Gaze

Use of 3-D human motion sensing without physical restrictions is the most promising approach to realize seamless coupling between virtual environments and the real world. Motion capturing without any specific markers by computer vision techniques is the most appropriate for such purposes. As the first step, we have developed an avatar motion control by user body postures, and we have applied it to 3D object manipulation in virtual environments. However, the biggest problem here is that the intention of the user can not be fully recognized only by human body postures, and that, sometimes, unintentional human motions cause unintended object manipulations and incorrect selection of the target object. Currently, we are introducing the user’s gaze to control 3D direct manipulation user interface. Using the gaze it becomes possible to control the user interface more accurately and efficiently. In this paper, we outline our gaze detection method based on computer vision techniques and its use to user interface after reviewing our framework of 3D direct manipulation user interface.
A new graphical user interface for a 3D topological mesh modeler

A New Graphical User Interface for a 3D Topological Mesh Modeler. (May 2008) David Victor Morris, B.E. D, Texas A&M University Chair of Advisory Committee: Dr. Ergun Akleman In this thesis, I present a new platform-independent, open source, intuitive graphical user interface for TopMod, an application designed for interacting with 3-dimensional manifold meshes represented by a Doubly Linked Face List (DLFL). This new interface, created using the Trolltech Qt user interface library, enables users to construct and interact with complex manifold meshes much faster and more easily than was previously possible. I also present a method for the rapid creation of a successful online community of users and developers, by integrating a variety of open source web-based software packages. The new website, which includes a discussion forum, a news blog, a collaborative user and developer wiki, and a source code repository and release manager, received an average of 250 unique visits per day during the first two months of its existence, and it continues to be utilized by a variety of users and developers worldwide.
Diabetes and stroke

The association between diabetes and stroke is well established. Recent large‐scale, international population studies suggest that diabetes is one of the most important modifiable risk factors for cerebrovascular disease. Despite this, we still have a relative paucity of evidence around the management of diabetes in stroke. The landscape is evolving and recent studies are helping establish best practice and suggesting new therapeutic opportunities. It is possible to develop a practical and clinical synthesis of the evidence around managing diabetes in adult patients with stroke and cerebrovascular disease, based on large trials, systematic reviews and guidelines, and focusing on the scenarios most often encountered in clinical practice. It is also important to recognise that there are common situations where robust evidence is lacking, but practical guidance for clinicians can be suggested. Copyright © 2019 John Wiley & Sons. Practical Diabetes 2019; 36 (4): 126–131
Testen Sie Ihr Fachwissen

malignem Melanom wurde bei seit einigen Tagen reduziertem Allgemeinzustand, starkem Husten und Koordinationsstörungen vorstellig. Der Patient hatte zum Aufnahmezeitpunkt insgesamt 4 Gaben des PD-1-Inhibitors Pembrolizumab erhalten (Erstgabe 4 Monate vor stationärer Aufnahme). Da man aufgrund der beschriebenen Symptomatik einen bronchopulmonalen Infekt vermutet hatte, war der Patient zuvor auswärts frustran i. v. antibiotisch behandelt worden. Bei uns wurde nun eine Computertomografie (CT) durchgeführt. Testen Sie Ihr Fachwissen Test Your Knowledge
Eigen analysis of wide-band fading channel impulse responses

An investigation of the complex path gain correlation properties of several types of wide-band channel impulse responses is presented. The correlation coefficients of the complex path gains of the channel's impulse responses exhibit a large range of values even for large path delay differences. This indicates that the autocorrelation matrix of the channel impulse responses is rarely diagonal, as often assumed in the study of frequency-selective fading channels. Also, using an eigendecomposition and subspace-based statistical signal processing on the autocorrelation matrix of the channel impulse responses, it is then shown that the propagation process is dominated by only a few orthogonal modes in many instances of channel propagation. The eigenvalues of the modes can be used as a measure of the actual diversity gain obtainable over the channels. From the receiver point of view, the dominant modes can be identified and used in the detection process to reduce the number of parameters to track. Among the channels studied, the wide-band conventional cellular and microcellular radio channels at 910 MHz for mobile applications and the wide-band indoor channels with fixed transmitter-receiver configurations at 950 MHz and 40 GHz are particularly important for today's and future applications. Several channel impulse response measurements have been analyzed to demonstrate these assertions.
Generative workload models of Internet traffic

With the World Wide Web (WWW) traffic being the fastest growing portion of load on the Internet, describing and characterizing this workload is a central issue for any performance evaluation study. We present a probabilistic attributed context free grammar (PACFG) as a model for translating from a user oriented view of the workload (namely the conversations made within WWW browser windows) to the methods submitted to the Web servers (respectively to a proxy server). The characterization at this lower level is essential for estimating the traffic on the net and are thus the starting point for evaluations of net traffic.
Do Hospital Closures Affect Patient Time in an Ambulance

among heart attack and trauma patients. 5,6 Intuition suggests that patients are in an ambulance longer after the nearest hospital closes, however, no one has previously measured the travel time change. Our study is the first we are aware of that measures change in time in an ambulance based on reported ambulance trips. We explore how hospital closures affect the time a patient travels from an incident location where 9-1-1 was called to the ED in an ambulance. Our study compares transport time in an ambulance one calendar year prior to and one calendar year after a hospital closes in the zip code of the incident. We study hospital closures in communities in the U.S., both rural and urban, for the years 2011-2014 where we have zip codes of hospital closures matched to ambulance call data.
Threat and Vulnerability Penetration Testing: Linux

A systematic approach to penetration testing of Redhat Linux operating system is described. Hacking is not an easy task, it requires high effort and perseverance to get access, the ability to gather information, skill of coding, and internetworking capability is a must. To prevent from intruders, penetration testing is a comprehensive effort to attempt breaking into a system. In this work the evaluation of performance system is built on Linux operating systems. It can be seen that penetration tests are a useful measurement to check the sanity of network infrastructure and hackable or not.
A General Contact Force Analysis of an Under-Actuated Finger in Robot Hand Grasping

This paper develops a mathematical analysis of contact forces for the under-actuated finger in a general under-actuated robotic hand during grasping. The concept of under-actuation in robotic grasping with fewer actuators than degrees of freedom (DOF), through the use of springs and mechanical limits, allows the hand to adjust itself to an irregularly shaped object without complex control strategies and sensors. Here the main concern is the contact forces, which are important elements in grasping tasks, based on the proposed mathematical analysis of their distributions of the n-DOF under-actuated finger. The simulation results, along with the 3-DOF finger from the ADAMS model, show the effectiveness of the mathematical analysis method, while comparing them with the measured results. The system can find magnitudes of the contact forces at the contact positions between the phalanges and the object.
Optimal Current Observer for Predictive Current Controlled Buck DC-DC Converter

In digital current mode controlled DC-DC converter, the conventional current sensor is either costly or has low accuracy. Thus, current observer, which could be realized based on digital circuit itself, is an ideal substitute for conventional current sensors. However, the observed current may diverge because of parasitic parameters. In this paper, an optimal current observer is proposed to solve the problem. Employing the optimal current observer based predictive current control, a buck converter, which shows preferable transient response than PID controlled converter is implemented. The effectiveness of the optimal current observer is experimentally demonstrated.
Liquid Biopsy as a Minimally Invasive Source of Thyroid Cancer Genetic and Epigenetic Alterations

In the blood of cancer patients, some nucleic acid fragments and tumor cells can be found that make it possible to trace tumor changes through a simple blood test called “liquid biopsy”. The main components of liquid biopsy are fragments of DNA and RNA shed by tumors into the bloodstream and circulate freely (ctDNAs and ctRNAs). Tumor cells which are shed into the blood (circulating tumor cells or CTCs), and exosomes that have been investigated for non-invasive detection and monitoring several tumors including thyroid cancer. Genetic and epigenetic alterations of a thyroid tumor can be a driver for tumor genesis or essential for tumor progression and invasion. Liquid biopsy can be real-time representative of such genetic and epigenetic alterations to trace tumors. In thyroid tumors, the circulating BRAF mutation is now taken into account for both thyroid cancer diagnosis and determination of the most effective treatment strategy. Several recent studies have indicated the ctDNA methylation pattern of some iodine transporters and DNA methyltransferase as a diagnostic and prognostic biomarker in thyroid cancer as well. There has been a big hope that the recent advances of genome sequencing together with liquid biopsy can be a game changer in oncology.
AD7716 LC2MOS 22-Bit Data Acquisition System

The on-chip control register is programmed using the SCLK, SDATA and TFS pins. Three bits of the Control Register set the digital filter cutoff frequency for the device. Selectable frequencies are 584 Hz, 292 Hz, 146 Hz, 73 Hz and 36.5 Hz. A further 2 bits appear as outputs DOUT1 and DOUT2 and can be used for controlling calibration at the front end. The device is available in a 44-pin PQFP (Plastic Quad Flatpack) and 44-pin PLCC. GENERAL DESCRIPTION The AD7716 is a signal processing block for data acquisition systems. It is capable of processing four channels with bandwidths of up to 584 Hz. Resolution is 22 bits and the usable dynamic range varies from 111 dB with an input bandwidth of 36.5 Hz to 99 dB with an input bandwidth of 584 Hz.
It Consumerization: Byod-Program Acceptance and its Impact on Employer Attractiveness

Many firms are considering ‘bring-your-own-device’ (BYOD) programs, under which their employees are allowed to bring their own devices to work and use them for both private and business purposes. This study examines what factors determine an employee's intention to participate in a corporate BYOD program and how such programs affect employer attractiveness. We approach our study of acceptance of corporate BYOD programs from the perspective of technology acceptance research. For this purpose, we propose a modified and extended UTAUT model. The model was tested by surveying students in their final term (n = 444). We show that performance expectancies have the strongest positive effect on intention, while perceived threats negatively impact intention. Finally, behavioural intention was positively associated with employer attractiveness, which leads to clear indications for companies considering establishing corporate BYOD programs. BYOD seems to play an increasingly important role in attracting and retaining future talent.
Screening and Diagnosing Frailty in the Cardiac and Noncardiac Surgical Patient to Improve Safety and Outcomes.

Frailty as a marker of aging has been well studied in the geriatric literature, where it has been established that chronological age does not necessarily correlate with biological age in terms of predicting patient outcomes. Over the past decade, the study of frailty has also flourished in the surgical and perioperative literature. This is fitting, given that the elderly population is the most rapidly growing segment in the United States, and by some estimates, more than half of all surgeries in the United States are performed on patients older than 65 years of age. Frailty has been associated with higher mortality, increased rates of postoperative complications, longer hospital stays, and higher rates of discharge to assisted living facilities. Identification of frail patients in the preoperative period has valuable implications across the perioperative spectrum. Specifically, it: allows clinicians to have more meaningful goals of care and risk-benefit discussions with patients and their families before surgery; expedites targeted interventions and allocation of resources to the patients who need it the most; and facilitates multidisciplinary team discussions on disposition planning.
Application of ensemble Kalmen filter in forecasting the electricity grid carbon factor.

Several publications have discussed the application of Ensemble Kalman Filter (EnKF) in history matching problems. The EnKF provides updated approximations based on the conditioned constraints to the historical data. In this paper we show how the EnKF is capable of forecasting/recovering the unpredictable trends of Electricity Grid Carbon Factor (EGCF). We adopt the EGCF scenario in the UK based on the available energy data provided by the Balancing Mechanism Reporting System (BMRS). We apply EnKF for forecasting the incomplete datasets in the UK EGCF in 2014. We present the ability of EnKF to recover the EGCF
Deakin University: Going Online At A Dual Mode University

Deakin is a dual mode university with more than half of its students doing at least part of their study at a distance and with an entrepreneurial arm that provides distance education services for even larger numbers. Online provision has been developing over a decade, enriching traditional distance education in programs with mixtures of on- and o-campus students. It has been supported by central services and corporate applications, leading to reasonable consistency in the thrust. A current aim is to ensure that it is sustainable at a high level of quality.
Uso de ontologías para la desambiguación de artefactos de software en la educción de requisitos de software

the problem of semantic ambiguity is transverse to various areas of knowledge, including requirements engineering. In many cases the requirements of a software are riddled with ambiguity due to the vagueness of the language, in this paper some technical semantic disambiguation are presented, including some techniques based on ontologies, and argues why the techniques based on ontologies should be used in the process of software requirements elicitation, and a practical case where a disambiguation of a requirements specification using a technique based on knowledge is presented: the algorithm Lesk.
Design and Implementation of a Memory Controller for Real-Time Applications

A memory controller is proposed where the behavior is predictable and which can be used for real-time systems. The memory controller is designed to be used in any system where a predictable memory controller is required, but integrates very well with AEthereal. It offers predictability per flow, which guarantees minimum bandwidth and maximum latency, without the necessity of simulation. Furthermore, the memory controller translates the peak memory bandwidth (gross bandwidth) to a net bandwidth, which is the effective available bandwidth for the IP blocks. The proposed solution has a worst-case gross-tonet bandwidth translation efficiency of 80%. The maximum latency for the highest priority requestor is 375ns. The memory controller is synthesized for CMOS12 and results in a small scalable memory controller with 0.04mm2 for 6 requestors.
Content Based Image Retrieval using Neural Network

Traditional methods of image retrieval using text are proven to be insufficient for the large image database. There are some drawbacks of Text based image retrieval, like assigning the labels to each image in large database using text is extremely time consuming and it is language dependent, valid for only one language at a time. Another drawback is for same image different users can assign different labels. These drawbacks can be avoided by using contents present in that image for retrieval of image. This type of retrieval of image is called as Content Based Image Retrieval. CBIR or Content Based Image Retrieval is the retrieval of images based on visual features such as color, texture and shape. There are two types of features present in an image, low level features and High level features. In CBIR, features of images stored in database are extracted and compared to the features of the query image. There are two important steps in CBIR, first is Feature extraction and second is Similarity meas- urement. An extensive set of experiments has been conducted to show that the new algorithm can improve the retrieval accuracy. In our project DML and ANN algorithms are used to measure the similarity between images. The experiment also indicates that the new algorithm(ANN) is more effective and more efficient than alternative algorithm.
The Diagnostic Value of Acute phase proteins in Barki Ewes with Pregnancy Toxemia

Pregnancy toxemia is a fatal metabolic disease resulting in high mortalities. The silent nature of the disease and lack of diagnostic tools decrease the chance of prediction and curing. In this paper we tried to find out the benefits of APPs, cytokines, and iron profile in diagnosis and prediction of the disease and their relation with other disease metabolic changes. Blood samples were collected from sixty barki ewes housed in Mattroh Research Station and were divided into 3groups; control, healthy late pregnant ewes, and pregnant toxemic ewes group. Biochemical analysis such as BHB, NEFA, Fb, Cp, Hp, SAA, Tf, Serum ferritin concentrations, Cytokines (IL-1α, IL-1β, IL-6,IL10, TNF-α) were measured and all the data were analyzed statically. The results confirmed that APPs and cytokines are valuable markers for pregnancy toxemia as they have a sensitivity and NPV as100% and high values of specificity, LR, PPV and accuracy rate. But APPs have higher percentages of increase than cytokines, especially Hp. Moreover, both of APPs and cytokines correlate well with other metabolic changes of the disease. Regarding the iron status, there was a significant decrease in mean concentrations of serum iron, ferritin, TF sat. % and a significant elevation in TIBC, UBIC and serum transferrin concentrationsin late pregnant ewes in comparison to control healthy group. On the other hand, the pregnancy toxemic ewes demonstrated a significant rise in the mean concentrations of serum iron, ferritin, TF sat. % and a significant drop in TIBC, UBIC and serum transferrin concentrations relative to the late pregnant group.
Assessment of wideband radio channels in alpine regions using PICAM

The authors describe measurements in the 900-MHz band carried out in the Innsbruck area with the real-time channel sounder RCS-900 of the Swiss PTT. The results are assessed for Groupe Speciale Mobile planning purposes using PICAM (path-loss and interference calculation for Austrian mobile radio), a network planning software package. Using measurements in Innsbruck, where elevation varies locally up to 200 m within a small area (10 km*10 km), reflection areas and network planning parameters were determined. Evaluation of the results shows that the three base stations are not sufficient even though they provide full field strength coverage. Certain areas (i.e. some segments) show strong interference for all three base stations due to time dispersion caused by reflections. Consequently, at least one additional site is necessary. It is demonstrated that PICAM can be used for various aspects of radio network planning by processing computer-based predictions and actual measurement results. <<ETX>>