Miracle-dz/UniFAR-FTUs huggingface dataset:
¿Es la diferencia de aniones fuertes un buen marcador de mortalidad en adultos con abdomen en tabla?

Introducción. Tradicionalmente, el ácido láctico, la proteína C reactiva y el déficit efectivo de base, se han utilizado para predecir la mortalidad en pacientes críticamente enfermos. La información es insuficiente cuando se utiliza la diferencia de aniones fuertes. En especial, no existen datos de pacientes con abdomen agudo. El objetivo de este estudio piloto fue evaluar el desempeño de la diferencia de aniones fuertes para predecir la mortalidad perioperatoria (30 días) en pacientes con abdomen en tabla, que requieren cirugía inmediata, en comparación con el ácido láctico, el déficit efectivo de base, la albúmina y la relación proteína C reactiva/ albúmina. Materiales y métodos. Para evaluar las características operativas de cada uno de los factores metabólicos en relación con la mortalidad periperatoria temprana, se determinó el área bajo la curva ROC (Receiver Operating Characteristics). Una vez obtenidos los mejores puntos de corte, se evaluó la asociación entre los sobrevivientes y los no sobrevivientes, mediante la prueba de ji al cuadrado (p<0,05). Resultados. Entre los factores metabólicos analizados, los que presentaron una mejor área bajo la curva ROC, fueron el ácido láctico (0,85) y el déficit efectivo de base (0,71). El área bajo la curva de la diferencia de aniones fuertes fue inferior (0,68), así como la de la diferencia aparente (0,68) y la diferencia efectiva (0,60). La relación proteína C reactiva/albúmina mayor de 5.000 g/L demostró un área bajo la curva ROC de 0,63. Se demostró diferencia estadística para el ácido láctico por encima de 4 mmol/L, la diferencia aparente de aniones fuertes menor de 40 mmol/L, la diferencia de aniones fuertes mayor de14 mmol/L y el déficit efectivo de base mayor de 7 mmol (p<0,05), entre sobrevivientes y no sobrevivientes. Conclusión. La diferencia de aniones fuertes (fuerte, aparente y efectiva) demuestra menores características operativas en pacientes con abdomen en tabla, cuando se correlaciona con la mortalidad posoperatoria temprana, en comparación con el ácido láctico y el déficit efectivo de base. La relación proteína C reactiva/ albúmina demuestra mejores características operativas que la diferencia de aniones fuertes y debe evaluarse en nuevos estudios.
A Structured Approach to VLSI Layout Design

A new approach to the VLSI layout problem is proposed that produces a structured floor plan for an arbitrary network of interconnected processing elements. It is based on extracting a minimum spanning tree from a given representation of a computation network and using an efficient, structured layout scheme for this minimum spanning tree. Techniques to lay out trees as arrays of layout slices are presented. It is assumed that the nodes of a network are identical in their layout size and connectivity. This method is valid at any level of a VLSI design since these nodes may represent gates, cells or complex macros. An application of this approach to modified tree networks is described. Other useful applications of the method are mentioned.
Ethical and Legal Issues in Canadian Nursing

This title provides students and practitioners with an up-to-date discussion of ethical and legal issues as they arise in everyday nursing practice in Canada. Features: * Explores such current topics as euthanasia, assisted suicide, living wills, organ donation, and patients' rights, using case studies as examples * defines national, provincial, and territorial legislation and regulations governing nursing practice * Includes a glossary of nursing terms
Molecular typing of Salmonella enteritidis strains isolated in several laboratory centers in Tehran by ERIC-PCR

پیات ی سیدیتیرتنا لانوملاس ياه هیوس یلوکلوم گن يروآ عمج زکرم دنچ زا هدش یهاگشیامزآ زا هدافتسا اب نارهت رهش شور ERIC-PCR ربجنر اضر 1 یبارت اضر ، 2 ، ا ییارزیم ریم 2 1 . اللها هیقب یکشزپ مولع هاگشناد ،یلوکلوم يژولویب تاقیقحت زکرم ) جع ( ناریا ،نارهت ، . ) لوئسم فلوم ( ، 82482556 021 ، ranjbarre@gmail.com 2 . اللها هیقب یکشزپ مولع هاگشناد ،یلوکلوم يژولویب تاقیقحت زکرم ) جع ( ناریا ،نارهت ،
Advances in asynchronous circuit theory. Part I : gate and unbounded inertial delay

Although the theory of asynchronous circuits (fates back to the early 1950s, considerable progress has been made in this area in the past five years. This paper constitutes the first part of a two-part survey of the recent advances in this field. Part I of the survey presents a unified and concise overview of those aspects of the theory that (leaf with the behavior of circuits under the assumption that delays in the circuit components and wires are unbounded. The historical development of the subject is presented, and some shortcomings of the earlier approaches are discussed. Ternary simulation is related to the binary analysis methods; the ternary approach is then used to correct the flaws in the earlier work. The question of realizability of sequential behaviors is then considered. It is shown that the class of realizable behaviors is rather severely restricted by the unbounded-delay assumption and that the use of bounded-delay models is more realistic. Part 11 of the survey will deal with bounded-delay models, MOS circuits, classical and delay-insensitive design methods, and complexity issues.
Combined coding-diversity (CCD) schemes for fading channels

To combat the effect of performance degradation due to the multipath fading, diversity techniques are known as the most advantageous procedure without increasing either the transmitted power or the bandwidth requirement. Combination of the coding, which is used for power-limited and band-limited channels, and diversity is a new aspect to exploit both for such channels as mobile radio. Some new combined coding-diversity (CCD) schemes are introduced, and simulated over uncorrelated Rayleigh fading which trellis detection and decoding simultaneously have been used.
Inovação em Software as a Service: funcionalidades em ferramentas de monitoramento de mídias sociais

This article aims to describe the launch of incremental innovation in social media monitoring software. The tactic, typical of SaaS (software as a service) products, is in line with the concept of perpetual beta, which is characteristic of social media and web 2.0. As a case study, we bring the reference to the release of network-based analysis modules in four service providers: Sysomos, Pulsar, Digimind, V-Tracker. It is proposed the relevance of the description and visibility of these organizational actors, especially as conditioning actors of interactive online environments through the relation between innovation and particularities of digital communication.
Influencia de los antiinflamatorios no esteroideos en la hemorragia digestiva por úlceras o erosiones gastroduodenales en pacientes con cirrosis hepática

INTRODUCTION: Peptic ulcer disease, with or without complications, is more common in patients with liver cirrhosis than in the general population. Factors associated with portal hypertension are involved in its pathogenesis. The prevalence of Helicobacter pylori infection in patients with liver cirrhosis and the general population is similar. The aim of the present study was to determine the influence of nonsteroidal antiinflammatory drugs (NSAIDs) in the etiology of bleeding peptic ulcer disease in patients with liver cirrhosis. PATIENTS AND METHODS: We studied 35 patients with liver cirrhosis and gastrointestinal bleeding due to gastroduodenal ulcers or erosions (group A), 125 noncirrhotic patients with gastrointestinal bleeding due to gastroduodenal ulcers or erosions (group B), and 70 patients with liver cirrhosis who were admitted to hospital without gastrointestinal bleeding (group C). All patients were questioned about NSAID consumption, including aspirin, during the week prior to hospital admission. RESULTS: NSAID consumption was reported by 15 patients (42.8%) in group A, 102 patients (58.2%) in group B, and 6 patients (8.5%) in group C. Statistically significant differences were obtained when the results for group A were compared with those for group C. CONCLUSIONS: NSAID consumption in patients with liver cirrhosis without gastrointestinal bleeding was low (8.5%) and was much lower than that observed in patients with cirrhosis admitted to hospital for bleeding due to gastroduodenal ulcers or erosions (42.8%). As occurs in the general population, NSAIDs play a significant role in the pathogenesis of bleeding due to peptic ulcer disease in patients with liver cirrhosis and portal hypertension.
Agotamiento profesional: concepciones e implicaciones en la salud pública

El agotamiento profesional ( burnout ) se describio originalmente como una condicion mental caracterizada por disminucion del desempeno laboral, sensacion de impotencia y frustracion e incapacidad para alcanzar objetivos o metas laborales. Para algunos autores, el agotamiento profesional es un conjunto de signos y sintomas mal definido, en tanto que para otros es una enfermedad en si misma y un problema potencial de salud publica. Se ha observado en todo el mundo que los profesionales y tecnicos mas afectados son aquellos que prestan servicios o asisten a otras personas, especialmente los dedicados a la atencion en salud. Este ensayo se centra en la idea de que el agotamiento profesional debe ser asumido como una enfermedad mas que como un sindrome; que sus referentes teoricos y metodologicos han variado a medida que han cambiado las definiciones de salud y enfermedad; que se detecta y se reporta cada vez mas, y que sigue siendo una condicion objeto de debate en diversos circulos cientificos donde se esgrimen posturas radicalmente opuestas que son materia de analisis aqui. Tras exponer las diversas concepciones en torno a esta condicion, el ensayo concluye con la exposicion de las implicaciones y las opciones de estudio del agotamiento profesional como enfermedad en funcion de las condiciones y los entornos que favorecen su aparicion entre los profesionales dedicados a la salud.
DNA Computing for an Absolute 1-Center Problem: An Evolutionary Approach

Deoxyribonucleic Acid or DNA computing has emerged as an interdisciplinary field that draws together chemistry, molecular biology, computer science and mathematics. Thus, in this paper, the possibility of DNA-based computing to solve an absolute 1-center problem by molecular manipulations is presented. This is truly the first attempt to solve such a problem by DNA-based computing approach. Since, part of the procedures involve with shortest path computation, research works on DNA computing for shortest path Traveling Salesman Problem, in short, TSP are reviewed. These approaches are studied and only the appropriate one is adapted in designing the computation procedures. This DNA-based computation is designed in such a way that every path is encoded by oligonucleotides and the path’s length is directly proportional to the length of oligonucleotides. Using these properties, gel electrophoresis is performed in order to separate the respective DNA molecules according to their length. One expectation arise from this paper is that it is possible to verify the instance absolute 1-center problem using DNA computing by laboratory experiments.
UNA EXTENSIN DE UML PARA EL MODELADO DE SERVICIOS WEB UML EXTENSION FOR WEB SERVICES MODELING

RESUMEN. Los servicios Web han surgido para proveer un marco basado en estándares, que permite la interacción de aplicaciones a través de la Web. A pesar de que existen varias tecnologías que facilitan el desarrollo de servicios Web y aplicaciones orientadas a servicios, la carencia de una base metodológica sólida para el desarrollo de tales aplicaciones, plantea la necesidad de nuevos métodos o técnicas de modelado que puedan garantizar la calidad en el desarrollo de este tipo de aplicaciones. MIDAS es un marco metodológico orientado a modelos para el desarrollo de SIWs, que está basado en UML, XML y tecnología objetorelacional y que propone el modelado del comportamiento del sistema basado en servicios Web. En este artículo se presenta una extensión de UML para el modelado de servicios Web, basada en el estándar Web Service Description Language (WSDL) propuesto por el W3C para la descripción de servicios Web. La extensión propuesta aporta una notación en UML que, por un lado, permite obtener una representación gráfica de un servicio Web y por otro, facilitará la generación automática de código WSDL a partir de un diagrama UML.
Testing Object-Oriented Software

From the Publisher: Object-oriented programming increases software reusability, extensibility, interoperability, and reliability. To realize these benefits you must use software testing. Software testing aims to uncover as many programming errors as possible with minimum cost. How to reduce the cost and improve the quality of software testing remains a major challenge to the software engineering community. The requirements for testing object-oriented programs differ from those for testing conventional programs. Testing Object-Oriented Software illustrates these differences and discusses object-oriented software testing problems, focusing on the difficulties and challenges testers face. The book provides a general framework for class-level and system-level testing and examines object-oriented design criteria and metrics of high testability. It offers object-oriented testing techniques, ideas and methods for unit testing, and object-oriented program integration-testing strategy. Readers are shown how they can drastically reduce regression test costs, presented with steps for object-oriented testing, and introduced to object-oriented test tools and systems. In addition to software testing problems, the text covers various test methods developers can use during the design phase to generate programs with good testability. The book's intended audience includes object-oriented program testers, program developers, software project managers, and researchers working with object-oriented testing.
Leukocytosis as a Paraneoplastic Phenomenon in Patients with Malignant Lung Tumors

Objective: leukocytosis as a paraneoplastic syndrome may occasionally occur in patients with lung carcinoma. The aim of the study was to assess the prevalence of leukocytosis in our sample of patients with lung carcinoma, to determine if leukocytosis is more common with a particular type of lung carcinoma, and whether leukocytosis caused inappropriate prescribing of antibiotics in patients with lung carcinoma. Methods: The study included 100 lung carcinoma patients treated at Department of Lung Diseases, General Hospital, during a three-year period (2003-2006). The methods of descriptive statistics were used on statistical analysis. Results: during a three-year period (2003-2006), 100 patients with lung carcinoma were treated at General Hospital, 23% of them with leukocytosis as a paraneoplastic phenomenon. Antibiotic therapy was prescribed in five of 23 (1,25%) patients. Conclusion: leukocytosis was most frequently associated with squamous cell carcinoma of the lung (43%), however, without statistical significance. Antibiotic therapy was prescribed in 1,25% of leukocytosis patients, suggesting that leukocytosis was correctly recognized as a araneoplastic phenomenon and was not unnecessarily treated with antibiotics.
A Comprehensive Framework for Comparing System Security Assessment Methods

With the increasing importance of system security risk assessment, a number of system security risk assessment methods or models have already appeared and more are emerging every day. Therefore it is difficult for organizations to select a method that best suits their requirements. The difficulty of selection drives the need toward a comparative framework to evaluate system security risk assessment methods. In the underlying research-in-progress paper we propose a comprehensive framework for comparing system security assessment methods. Unlike most of the existing comparative framework, the proposed framework covers the whole process of system security risk assessment based on the evaluation criteria of completeness and effectiveness. In our future research, three current system security risk assessment methods will be evaluated using the proposed comparative framework. This framework will highlight the strengths and weaknesses of the methods compared.
FAKTOR-FAKTOR YANG MEMPENGARUHI AUDIT DELAY

Penelitian ini bertujuan untuk menguji dan memperoleh bukti empiris tentang pengaruh opini audit, kualitas auditor, ukuran perusahaan, klasifikasi industri dan solvabilitas terhadap audit delay. Data dalam penelitian ini adalah laporan keuangan perusahaan dan laporan auditor independen yang diperoleh dari website Bursa Efek Indonesia (www.idx.co.id). Pemilihan sampel pada penelitian ini menggunakan teknik purposive sampling dan menghasilkan 740 perusahaan sampel yang terdaftar di Bursa Efek Indonesia selama tahun 2012 dan 2013. Metode analisis regresi berganda digunakan untuk menganalisis data. Hasil penelitian menunjukkan bahwa kelima variabel independen tersebut berpengaruh terhadap audit delay. Kata kunci: Audit delay, opini audit, kualitas auditor, ukuran perusahaan, klasifikasi industri, dan solvabilitas.
Transgresiones sexuales, tradiciones discursivas y oralidad en el castellano medieval

espanolLas dificultades que supone hablar de transgresiones sexuales en el castellano medieval invitan a buscar respuestas en los fundamentos de la propia cultura medieval y en el proceso de escrituralizacion de la lengua. En la primera me servi de la evolucion de la formulacion teologica y canonica del cristianismo y de su impronta en la elaboracion del derecho comun y en la moral social para explicitar los parametros a partir de los cuales se puede definir el concepto de transgresion sexual en la epoca objeto de estudio. En el plano estrictamente lexico, analice la evolucion de su formulacion verbal, pero, en este caso, como reflejo del proceso de escrituralizacion y en consonancia con las caracteristicas de la tradiciones discursivas, permeables, primero, a la oralidad, opuestas en un segundo momento y claramente favorables a ella cuando la lengua literaria se doto de recursos y de generos que le permitian reproducir las condiciones del intercambio comunicativo. EnglishThe study of sexual transgression from a linguistic perspective entails some difficulty when applied to the medieval Castilian language. Such complexity calls for specific insights, based both on the search for the foundations of medieval culture as well as on the consideration of the writing process undergone at large by this language. This article has, therefore, paid attention to the evolution of the theological and canonical Christian formulation and to its effects on the parallel configuration of common law and social mores, all of which will help us understand the defining frames of sexual transgression at that time. As for the lexical field, I have analyzed the verbal evolution of transgressive sexual formulae, according to that of the language from its oral stage into the written mode. I have Also taken into account the characteristics of some discourse traditions, as these changed in their response to orality from permeability to rejection and to further acceptance (once the literary language was endowed with the devices and genres that allowed the proper enactment of the communicative exchange pattern).
Impacto femoroacetabular: uma das condicoes precursoras da osteoartrose do quadril

Hip osteoarthrosis (OA) is classically divided into two main groups: primary or “idiopathic”, and secondary. Mechanisms responsible for primary hip joint OA have remained unclear for many years. Studies by Reinhold Ganz et al, from Bern, Switzerland, have pointed to suggestive clinical evidence that femoroacetabular impingement ( FAI) is an etiological factor for early degenerative changes that progress to OA, thus being responsible for those lesions previously rated as idiopathic. Authors present FAI terminology, mechanisms, pathoanatomy, diagnostic methods and treatment through extensive literature review. They stress the existence of factors showing that, with early treatment, triggering of hip joint osteoarthritis or hip joint arthritis progression speed can be reduced.
La malaria en Colombia, Antioquia y las zonas de Urabá y Bajo Cauca: panorama para interpretar la falla terapéutica antimalárica. Parte 2

Problem: in the past 5 years we have studied the treatment response to antimalarials and their combinations in the Antioquia region (Turbo, Zaragoza and El Bagre municipalities). The interpretation and better understanding of the treatment outcome (adequate clinical response, early treatment failure or late treatment failure) require further information since this response depends on host’s and parasite’s factors, independently of the characteristics of the antimalarial administered. Objectives: to define an adequate reference frame which allows for interpretation of results obtained during antimalarials treatment assessment studies. This would include demography, epidemiology, climatic and social-economic information about Colombia, Antioquia, the regions of Uraba, Bajo Cauca and the municipalities of Turbo and El Bagre. Methodology: research of secondary information (publications reports and internet resources), and some primary information (taken from Sistema de Vigilancia Epidemiologica de Antioquia (Sivigila) of Direccion Seccional de Salud de Antioquia DSSA). Data about treatment response were primary information (produced by Grupo Malaria, Universidad de Antioquia), or obtained from other authors. With the gathered data, tables and graphs were produced and calculations were carried out using other variables. Results: the frequency of malaria is presented for Colombia during the period 1960-2002 and the results of the malaria eradication and control programs, and their failure, are described. Similarly, the frequency of malaria in Antioquia during 1959-2003 is discussed and presented in terms of incidence rates and parasite annual indexes (PAI). Non adjusted and adjusted rates and PAI were obtained, therefore adjusted rates are presented by exposed population, which is less of 20%. Adjusted results are 5-6 fold higher that non-adjusted values in Antioquia. However this is not true for the Uraba and Bajo Cauca regions, where 100% of the population is exposed to malaria. Malaria incidence in Antioquia is increasing. The mean PAI for the period 1996-2002 was 54,08‰ in Turbo and 111,20‰ in El Bagre. Malaria is described considering patient’s gender and age, in Antioquia as well as in Turbo and El Bagre. A review of the findings about treatment failure in Plasmodium falciparum malaria is presented and some recommendations about the use of antimalarials are outlined.
Hypothalamische Adipositas bei Kraniopharyngeom im Kindes- und Jugendalter

Zusammenfassung Kraniopharyngeome sind seltene embryonale Mittellinienfehlbildungen mit raumforderndem Charakter. Bei häufig langer Anamnesedauer sind Leitsymptome der Erkrankung: Sehstörungen, Kopfschmerzen, Wachstumsstörungen und Polyurie/Polydypsie (Diabetes insipidus neurohormonalis). Der Versuch einer kompletten Resektion unter Wahrung der optischen und hypothalamisch-hypophysären Funktion stellt die Therapie der ersten Wahl bei günstiger Lokalisation des Fehlbildungstumors dar. Bei ungünstiger Lokalisation (Hypothalamusbeteiligung) wird eine begrenzte Resektion mit anschließender Strahlentherapie empfohlen. Bei hoher Überlebensrate (93 %) wird die Lebensqualität der Patienten insbesondere durch eine hypothalamische Adipositas beeinträchtigt. Die Therapieoptionen zur Behandlung der hypothalamischen Adipositas sind eingeschränkt, so dass der Prävention therapiebedingter hypothalamischer Läsionen eine besondere Bedeutung zukommt.