Miracle-dz/UniFAR-FTUs huggingface dataset:
Dimensions et régularité directionnelles du courant de Green

Cette these concerne les proprietes dynamiques des endomorphismes holomorphes du plan projectif complexe. La premiere partie introduit et minore les dimensions directionnelles du courant de Green. Nos resultats menent une analyse multifractale des tranches de ce courant par des coordonnees locales, relativement aux mesures ergodiques dilatantes. Une premiere application montre que, relativement a toute mesure ergodique de grande entropie, tout courant positif ferme possede une dimension directionnelle strictement plus grande que deux, ce qui repond a une question de de Thelin-Vigny. Comme deuxieme application, nous decrivons les dimensions directionnelles du courant de Green des endomorphismes semi-extremaux de Dujardin, c'est a dire ceux dont la mesure d'equilibre est absolument continue par rapport a la mesure trace du courant de Green. Dans la deuxieme partie, nous majorons les dimensions directionnelles du courant de Green en utilisant des techniques de Theorie du pluripotentiel. En combinant ces resultats a ceux de la premiere partie, nous montrons une propriete de separation des dimensions directionnelles du courant de Green relativement a la mesure d'equilibre. Dans la derniere partie, nous etudions la regularite des tranches du courant de Green dans deux situations semi-extremales. Nous montrons que la derivee de Radon-Nikodym des tranches stables est bornee presque partout. Cette propriete, proche de l'absolue continuite par rapport a la mesure de Lebesgue, apporte une precision a nos resultats precedents. Les techniques utilisees ont egalement permis d'obtenir une nouvelle majoration de la dimension locale des mesures ergodiques dilatantes. Cette majoration nous rapproche de la conjecture de Binder-DeMarco concernant la dimension de la mesure d'equilibre.
A RANDOMIZED STUDY COMPARING THE EFFECT OF STANDARD VERSUS SHORT INCUBATION OF SPERM AND OOCYTE ON SUBSEQUENT PREGNANCY AND IMPLANTATION RATES FOLLOWING IN VITRO FERTILIZATION EMBRYO TRANSFER

Some data suggest that some sperm are associated with a toxic product that lowers embryo implantation rates when these sperm come in contact with the zona pellucida. The possibility exists that shortening the incubation time could improve pregnancy rates. A randomized prospective study was initiated to evaluate pregnancy and implantation rates with transfer of embryos formed by conventional overnight vs short (2-h) co-incubation of sperm and oocytes. The clinical and viable pregnancy rates were 41 and 29% for conventional co-incubation versus 30 and 30% for short co-incubation. Implantation rates were also similar (17.9 vs 17.8%). Short incubation does not seem to impact any advantage over conventional co-incubation techniques in couples undergoing in vitro fertilization where the male factor is normal.
Modelling of wave propagation in rough mine tunnels

A new technique is applied to the modelization of radio waves propagation in mine tunnel having lossy dielectric side walls of random roughness. The resultant model takes into account the spatial variability of the electromagnetic waves in non canonical rough mine tunnels and makes use of the cascade impedance method (CIM) to predict the propagation behavior. Two (2-D) and three dimensional (3-D) propagation models were obtained and compared with experimental data.
Alcohol consumption and digestive tract cancer

Purpose of review The data indicating that alcohol is an important factor increasing the risk to develop gastrointestinal cancer are consolidating. The purpose of this review is to summarize current evidence. Recent findings Acetaldehyde is the first metabolite of ethanol metabolism and has direct carcinogenic and mutagenic effects by modifying DNA via generation of DNA adducts. Oxidative stress has a prominent role in triggering chronic inflammation and carcinogenesis through formation of reactive oxygen species. Recently published large prospective cohort studies with sufficient statistical power and meta-analyses could refine the knowledge regarding the impact of alcohol on gastrointestinal cancer. Functional genetic variants of alcohol-metabolizing enzymes proved to be associated with increased risk for esophageal and gastric cancer. The highest risk increase for malignancy was observed in the upper aerodigestive tract (oral cavity, pharynx, larynx) and esophagus (squamous cell carcinoma), weaker correlations were established regarding gastric, pancreatic, and colorectal neoplasias. Summary Alcohol overconsumption is a serious avoidable risk factor for the development of gastrointestinal tract cancer, both alone but even more in combination with other risk factors such as tobacco and obesity.
Prevalence of, and attitude towards, needle-stick injuries by Nigerian gynaecological surgeons.

UNLABELLED Health care workers who have occupational exposure to blood and other potentially infectious materials are at increased risk for acquiring blood-borne infections. The emotional impact of a needle-stick injury can be severe and long lasting, even when a serious infection is not transmitted. OBJECTIVE To assess the prevalence and attitude towards needle-stick injuries by Nigerian gynaecological surgeons. METHODOLOGY A cross-sectional study was conducted at the 40th Annual General Meeting and Scientific Conference of the Society of Gynaecology and Obstetrics of Nigeria (SOGON) held in Ibadan, southwest Nigeria from the 23rd to the 26th of November 2005. Data was collected using a self-administered questionnaire. RESULTS Seventy two questionnaires out ofa hundred administered were finally analysed. Sixty-five (90.3%) respondents had experienced needle-stick injuries in the workplace. This occurred in the majority of cases (86.2%) during suturing. Only 9.2% of those experiencing a needle-stick injury took the correct or appropriate action afterwards. Consultants were not significantly more likely than Residents to take appropriate actions after needle-stick injuries (p > 0.10, X2 = 2.11, 1 df). Fifty-two (80%) of those with needle-stick injuries did not report the incident to the appropriate office. Only 26 (37.1%) of 70 respondents indicated the presence of a needle-stick policy in their centres. CONCLUSION The prevalence of needle-stick injuries among sampled Nigerian gynaecological surgeons is high. Majority are either unaware or do not take appropriate actions after exposure to hazardous body fluids from needle-stick injuries, either through first-aid steps or post-e4posure prophylaxis. All health institutions should have a working needle-stick policy in their centres, and health care workers continually educated on it.
Type 1 versus Type 2 calreticulin mutations in essential thrombocythemia: A collaborative study of 1027 patients

CALR (calreticulin) trails JAK2 as the second most mutated gene in essential thrombocythemia (ET). Mutant CALR in ET is a result of frameshift mutations, caused by exon 9 deletions or insertions; type‐1, 52‐bp deletion (p.L367fs*46), and type‐2, 5‐bp TTGTC insertion (p.K385fs*47) variants constitute more than 80% of these mutations. The current study includes a total of 1027 patients divided into test (n = 402) and validation (n = 625) cohorts. Among the 402 ET patients in the test cohort, 227 (57%) harbored JAK2, 11 (3%) Myeloproliferative leukemia virus oncogene (MPL), and 114 (28%) CALR mutations; 12% were wild‐type for all three mutations (i.e., triple‐negative). Among the 114 patients with CALR mutations, 51 (45%) displayed type‐1 and 44 (39%) type‐2 variants; compared to mutant JAK2, both variants were associated with higher platelet and lower hemoglobin and leukocyte counts. However, male sex was associated with only type‐1 (P = 0.005) and younger age with type‐2 (P = 0.001) variants. Notably, platelet count was significantly higher in type‐2 vs. type‐1 CALR‐mutated patients (P = 0.03) and the particular observation was validated in the validation cohort that included 111 CALR‐mutated ET patients (P = 0.002). These findings, coupled with the recent demonstration of preferential expression of mutant and wild‐type CALR in megakaryocytes, suggest differential effects of CALR variants on thrombopoiesis. Am. J. Hematol. 89:E121–E124, 2014. © 2014 Wiley Periodicals, Inc.
Insecticidal activities of their components derived from the essential oils of Cinnamomum sp. barks and against Ricania sp. (Homoptera: Ricaniidae), a newly recorded pest.

BACKGROUND Insecticidal activities of Cinnamomum cassia and Cinnamomum zeylanicum oils and their components are not known against Ricania sp. Insecticidal activities of major components derived from C. cassia and C. zeylanicum oils were examined in spray and leaf-dipping bioassays against Ricania sp. nymphs and adults. RESULTS The LC50 value of C. cassia and C. zeylanicum oils was 37.66 and 72.62 mg L-1 , respectively, in leaf-dipping bioassays against Ricania sp. nymphs, and 77.38 and 134.86 mg L-1 in spray bioassays against Ricania sp. adults. The insecticidal activity of C. cassia oil was 1.74-1.93 times greater than that of C. zeylanicum oil. When examined by gas chromatography mass spectrometry, the cinnamaldehyde content of C. cassia and C. zeylanicum oils was 80.20% and 46.32%, respectively. Based on the LC50 values of cinnamaldehyde, hydrocinnamaldehyde and 4-hydroxy-3-methoxycinnamaldehyde against Ricania sp. nymphs and adults, cinnamaldehyde (LC50 , 31.25 and 62.43 mg L-1 ) demonstrated the most potent insecticidal activity, followed by 4-hydroxy-3-methoxycinnamaldehyde (172.19 and 212.77 mg L-1 ) and hydrocinnamaldehyde (275.05 and 318.63 mg L-1 ). CONCLUSION The findings revealed that C. cassia oil, C. zeylanicum oil and cinnamaldehyde have potential value in the management of Ricania sp. and could be valuable as effective insecticides. © 2017 Society of Chemical Industry.
Kantian minds and humean minds: how to read the analogies of experience in reverse

It is nowadays a commonplace of Kant-interpretation that Kant's response to Hume in the Analogies of Experience is not strictly speaking a refutation of Hume but in fact only an extended critical response to Hume's skeptical accounts of object-identity and causation, that also accepts many of Hume's working assumptions. But this approach can significantly underestimate the extent to which Kant's conception of the representational mind is radically distinct from Hume's. In particular, Kant's conception of the human mind's innately-specified spontaneous actions as ultimate sources of the veridical representation of both logical and metaphysical necessity in the world of objective experience, if correct, entails a flat-out rejection of Hume's conception of the human mind's merely projectivist abilities and activities. This in turn entails that, to this extent, the Analogies contain not only a critical response to Hume, but also a flat-out refutation of Hume.
1 Tactile Sensors for Measuring Effects of Sight , 2 Movement , and Sound on Handgrip Forces during 3 Hand-Tool Interaction 4

Using tactile sensing to measure grip force variations during hand-tool interaction 10 reveals effects of sensory feed-back signals on individual handgrip forces in surgical simulator 11 training. A biosensor system was designed for recording grip-force signals from different loci of 12 measurement in the palm, the fingers, and the fingertips of the dominant and non-dominant hands 13 of eleven novice surgeons. To test for effects of sound, movement, and sight on grip force signals, 14 subjects had to pick up two tools, then hold them still or move them upwards and downwards for 15 ten seconds while listening to soft or hard musical tones, with their eyes open and blindfolded. We 16 found significant effects of movement, sight, and sound on average maximum peak forces. 17 Stronger grip force signals were recorded from the dominant hand moving the tools. In specific 18 sensor loci in the fingertips, significantly stronger grip forces were recorded in the absence of visual 19 input (blindfolded condition). Grip forces recorded from the palm of the hands were significantly 20 stronger with exposure to hard musical tones. It is concluded that handgrip force is significantly 21 influenced by sensory signals from the auditory and visual sensory modalities. Such interactions 22 could be effectively exploited for guiding simulator training. 23
An Additional Patient With 3q27.3 Microdeletion Syndrome

The 3q27.3 microdeletion syndrome has been recently delineated in 7 subjects from 5 families sharing a 1.4 Mb smallest region of overlap. This condition appears recognizable by the association of Marfanoid habitus, mild but distinctive facial dysmorphism, intellectual disability, psychosis, and mood disorder. Here, we describe an additional 17-year-old man with an ~7.7-Mb deletion encompassing the 3q27.3 microdeletion critical region, previously run undetected at standard karyotyping. The constellation of major clinical findings overlaps with those reported in the 7 previously published patients and thus confirms the existence of a strongly recognizable syndrome linked to imbalance of 3q27.3. The role of AHSG and, possibly, of other genes in determining the3q27.3 microdeletion habitus is discussed by comparison of the deleted segments. The involvement of adjacent loci and genes, such as OPA1 and GP5, may contribute in this patient to novel satellite features, such as optic atrophy and subclinical coagulopathy.
The manifestations and treatment of poisoning due to nerve gas and other organic phosphate anticholinesterase compounds.

THE NERVE gases are a group of highly toxic organic esters of phosphoric acid derivatives which have physiologic effects attributable to the inhibition of cholinesterase enzymes. The effects resemble those produced by physostigmine and neostigmine (Prostigmin) but are more intense and more prolonged. The nerve gases are among the most toxic of the chemical warfare agents, and they are the most adaptable to long-range attack, as upon civilian populations. 1 A number of related but somewhat less toxic organic phosphate anticholinesterase compounds have proved to be useful in medicine and in agriculture. Diisoprophyl fluorophosphate (DFP) has been studied in detail* and has been employed as a therapeutic agent in the management of abdominal distention,† urinary retention, and glaucoma. 6 Tetraethylpyrophosphate (TEPP) 7 and octamethyl pyrophosphoramide (OMPA) 8 proved to be of some value in the management of myasthenia gravis, but they have been replaced by less potent anticholinesterase compounds. Parathion, bis-(monoisopropylamino)-fluorophosphine
Global Loss Evaluation Methods for Nonsinusoidally Fed Medium-Frequency Power Transformers

Medium-voltage conversion systems, such as traction and grid-connected converters, are continuously evolving toward higher power densities. Consequently, volume, weight, and material reductions are becoming major design issues, which lead the research focus toward high-/medium-frequency isolated power conversion systems. An optimized design of these conversion systems requires a detailed transformer-loss evaluation considering both copper and core losses. This paper presents a simple and flexible methodology to analyze global medium-frequency transformer losses in an isolated DC-DC converter fed by general nonsinusoidal waveforms. Various loss evaluation approaches are considered, pointing out their validity and limitations by means of finite-element simulations and experimental tests.
Pattern-Aware Dynamic Thread Mapping Mechanisms for Asymmetric Manycore Architectures

Recent factors in the architecture community such as the power wall and on-chip complexity have caused a shift to manycore architectures and multi-threaded workloads. An emerging architecture for general purpose processing is an asymmetric chip layout composed of cores with varying levels of complexity and power. This work considers thread behavior that results from parallel programs and proposes four new thread mapping schemes for this asymmetric architecture. These schemes leverage the behavior of common programming patterns used in parallel programming to target typical thread behavior. The patterns targeted include the pipeline parallelism, divide and conquer, and recursive data patterns. The proposed predictors out-perform base asymmetry aware schemes by at most 40% and existing dynamic schemes by as much as 23% for the PARSEC and SSCA2 benchmarks. Additionally, this work demonstrates the relationship between thread heterogeneity and the parallel pattern used to create the workload, thus creating a link between programmer and architect that can be leveraged to create more intelligent thread mapping schemes.
Sonographic measurement of the fetal femur: Factors affecting accuracy

Variations have been observed in the measurement of fetal femoral diaphysis length by ultrasound. This in vitro study examines the effect of depth, the angle of the bone relative to the axis of the sound beam, the machine, and the observer on the precision of measurement. Using analysis of variance techniques, it demonstrates that three of these factors (depth, angle, and machine) have significant effects. Depth‐associated variations were less than one millimeter and are probably not of clinical importance. However, the variations due to changes in angle are highly significant (P = <0.001:1 and may be controlled by obtaining the measurement with the femur perpendicular to the sound beam. Errors due to variation between machines were also highly significant (P = <0.001). When determining serial growth patterns, the errors due to variations between machines can be controlled by using the same machine for each examination. The variation between machines is also an important factor to consider when choosing a curve for reference purposes.
Direct Interaction of a Ca2+-binding Loop of Synaptotagmin with Lipid Bilayers*

Synaptotagmin 1 binds Ca2+ and membranes via its C2A-domain and plays an essential role in excitation-secretion coupling. In this study, we sought to identify Ca2+- and membrane-induced local conformational changes in the C2A-domain of synaptotagmin and to delineate the C2A-lipid binding interface. To address these questions native phenylalanine residues were replaced, at each face of the domain, with tryptophan reporters. Changes in tryptophanyl fluorescence indicated that Ca2+induced long range conformational changes throughout C2A, including regions distant from an established Ca2+-binding site. Addition of liposomes resulted in Ca2+-dependent increases in the fluorescence of tryptophans 193, 231, and 234. Only the tryptophan residues at positions 234 and 231, which lie within a Ca2+-binding loop of C2A, exhibited liposome-induced blue shifts in their emission spectra. Quenching experiments, using membrane-imbedded doxyl spin labels, revealed that tryptophan residues 231 and 234 penetrated lipid bilayers. These data delineate the lipid binding interface of C2A and provide the first evidence for adjacent Ca2+- and lipid-binding sites within a C2-domain. The penetration of C2A into membranes may function to bring components of the fusion machinery into contact with the lipid bilayer to initiate exocytosis.
A EPISTEMOLOGIA DO CAMPO ABERTO E O ORGANIZAR DAS PRÁTICAS DE ESPAÇO

Neste ensaio colocamos em discussao a ontoepistemologia de processos de Robert Cooper, articulando-a as contribuicoes e proposicoes de Theodore R. Schatzki e Michel de Certeau para refletir sobre a ideia das praticas organizadoras de espacos no campo dos Estudos Organizacionais. Em um primeiro momento, delimitamos o contexto precursor resgatando brevemente os principais pontos do metodo weberiano da compreensao empatica e suas relacoes com a analise da experiencia vivida. Apos, e segundo Cooper (1976), articulamos a questao do campo aberto (open field), enfatizando o modo de uso em nossa vida diaria da acao organizada (organizing action). Em seguida, consideramos as abordagens da virada pratica (practice turn), iluminando as dimensoes relacionadas as praticas de espaco segundo Schatzki (2002) e Certeau (2008). Por fim, sugerimos a ideia do organizar das praticas de espaco enquanto processos abertos, finalizando com as contribuicoes para os Estudos Organizacionais.
Characterization of transition edge sensors for the Millimeter Bolometer Array Camera on the Atacama Cosmology Telescope

The Atacama Cosmology Telescope (ACT) aims to measure the Cosmic Microwave Background (CMB) temperature anisotropies on arcminute scales. The primary receiver for ACT is the Millimeter Bolometer Array Camera (MBAC). The MBAC is comprised of three 32×32 transition edge sensor (TES) bolometer arrays, each observing the sky with an independent set of band-defining filters. The MBAC arrays will be the largest pop-up detector arrays fielded, and among the largest TES arrays built. Prior to its assembly into an array and installation into the MBAC, a column of 32 bolometers is tested at ~ 0.4 K in a quick-turn-around dip probe. In this paper we describe the properties of the ACT bolometers as revealed by data from those tests, emphasizing a characterization that accounts for both the complex impedance and the noise as a function of frequency.
Comparison of B-Cell Activating Factor Expression in Neutrophils in Patients with Potentially Malignant Disorders and Patients with Cancer in the Same Site.

BACKGROUND B-cell activating factor (BAFF) belongs to the TNF superfamily of proteins, which influences the life span of normal and malignant cells. It has been demonstrated that there is an overexpression of BAFF in peripheral blood neutrophils and mononuclear cells in patients with oral squamous cell carcinoma (OSCC), suggesting a tumor-promoting activity of those cells. Taking into consideration that numerous OSCC cases are preceded by clinically evident oral potentially malignant disorders (OPMDs), involving e.g., oral lichen planus (OLP), we have examined the expression of BAFF molecule in the cells of patients with OLP, compared to the expression thereof in the cells of patients with OSCC. METHODS Real-time PCR and western blot analysis confirmed significantly increased mRNA levels of BAFF in neutrophils of patients with OSCC and showed that it also increased in the cells of patients with OLP. Cells of patients with OSCC after treatment demonstrated a reduced expression of BAFF protein, but in the cells of patients with OLP after treatment we found increased expression of BAFF. RESULTS LPS-stimulation led to reduced expression of BAFF protein in cells of all patients, before and after treatment and simultaneous increased expression of IκB, at mRNA and protein levels. CONCLUSIONS Overexpression of BAFF demonstrated in neutrophils of both examined patient groups suggests that this molecule may be a factor linking oral lichen planus with oral squamous cell carcinoma, favoring the malignant transformation of OLP to OSCC. Furthermore, results obtained herein suggest that LPS may not only inhibit, but may even reduce BAFF expression in neutrophils of OLP patients.