Miracle-dz/UniFAR-FTUs huggingface dataset:
Sensor nodes localization based on inequalities of electric field intensity

Using simultaneous inequalities of electric field intensity observed between sensor nodes during radio communication, the nodes positions are estimated. The multidimensional scaling (MDS) method which is often used in sensitivity measurement is improved to solve sensor nodes localization problem. In the improved MDS, sensor nodes and base nodes those positions are known are dealt separately, and the initial arrangement is set by a method which is suitable for this method. We use two simple radio propagation model which describe the characteristics of electric field intensity approximately. Using these models, computer simulations are executed, and these results reveal that it is possible to estimate sensor nodes positions with high accuracy when reflection and blocking of radio waves are not occurred
EMOTIONS FOR THE NECESSARY

Emotional relationships with material objects can not be thought as isolated from social and material conditions of existence. This paper is an attempt to introduce the question of economic means into debates on “design and emotion”. It firstly addresses the role of economic means in crediting objects with emotions and subsequently evaluates approaches of ‘design and emotion’ with regard to varied meanings and ways of forging emotional relationships with objects, which is largely shaped by material conditions of existence. Based on individual interviews, it was found that economically deprived people tend to articulate “emotions for the necessary” through a narrative on material objects which privileges necessities. Yet, ‘design and emotion’ movement, basing itself on a divorce between function and emotion and dissociating emotions from the world of necessities, excludes those emotions for the necessary. Alındı: 08.02. 2008; Son Metin: 22.04. 2008 Anahtar Sözcükler: duygular ve gereksinimler; duygular ve ekonomik olanaklar; tasarım ve duygular; duygusal
Stress From the Neonatal Intensive Care Unit to Home: Paternal and Maternal Cortisol Rhythms in Parents of Premature Infants

To examine cortisol diurnal rhythms over the transition from the critical care setting to home for fathers and mothers of very low-birth-weight infants, including how cortisol is associated with psychosocial stress and parenting sense of competence. This cohort study in a level III neonatal intensive care unit and the general community had 86 parents complete salivary collection and self-reported psychosocial measures. Salivary samples were collected 3 times a day on the day before discharge, and on 3 subsequent days at home. Self-report measures included the Perceived Stress Scale and the Parenting Sense of Competence Scale, which measure parenting satisfaction. Fathers showed increased physiologic stress over the transition home, reflected by flattening of slopes, lower wakeup, and higher bedtime cortisol. Mothers reporting increases in perceived stress over the transition home had higher bedtime cortisol, suggesting a link between higher perceived stress and higher physiologic stress. Results were significant after controlling for breastfeeding, insurance status, and gestational age. This study examined a physiologic marker of stress in parents with very low-birth-weight infants, finding sex disparities in diurnal cortisol patterns during the transition from neonatal intensive care unit to the community. Fathers may be especially susceptible to stressors during this transition.
Modifying Perceived Size of a Handled Object through Hand Image Deformation

In this study, we aim to construct a perception-based shape display system to provide users with the sensation of touching virtual objects of varying shapes using only a simple mechanism. Thus far, we have proved that identified curved surface shapes or edge angles can be modified by displacing the visual representation of the user's hand. However, using this method, we cannot emulate multifinger touch, because of spatial unconformity. To solve this problem, we focus on modifying the identification of shapes using two fingers by deforming the visual representation of the user's hand. We devised a video see-through system that enables us to change the perceived shape of an object that a user is touching visually. The visual representation of the user's hand is deformed as if the user were handling a visual object; however, the user is actually handling an object of a different shape. Using this system, we conducted two experiments to investigate the effects of visuo-haptic interaction and evaluate its effectiveness. One is an investigation on the modification of size perception to confirm that the fingers did not stroke the shape but only touched it statically. The other is an investigation on the modification of shape perception for confirming that the fingers dynamically stroked the surface of the shape. The results of these experiments show that the perceived sizes of objects handled using a thumb and other finger(s) could be modified if the difference between the size of physical and visual stimuli was in the −40% to 35% range. In addition, we found that the algorithm can create an effect of shape perception modification when users stroke the shape with multiple fingers.
Analyse économétrique des décisions de production des propriétaires forestiers privés non industriels en France

La production de bois integre notamment des enjeux economiques, climatiques et energetiques. En France, selon les donnees de l'Institut National de l'Information Geographique et Forestiere, l'accroissement biologique de la foret est largement superieur aux prelevements de bois. C'est pourquoi l'Etat francais a fixe l'objectif de prelever 21 millions de m3 supplementaires de bois d'ici 2020 (Grenelle de l'environnement, 2007). Cependant, la foret francaise appartient majoritairement a des proprietaires forestiers prives qui ont des preferences a la fois pour le revenu issu de la vente de bois et pour les amenites non-bois. Les politiques visant a accroitre la production de bois doivent donc integrer ces aspects. L'objectif de ce travail de these est de comprendre les determinants de la production jointe de bois et d'amenites non-bois en France. Pour ce faire, nous nous sommes d'abord interesses aux determinants individuels et regionaux de l'offre de bois. Nous montrons que le comportement d'offre de bois d'un proprietaire peut varier en fonction du comportement de production de bois constate chez ses pairs (effets sociaux). Ensuite, nous mettons en evidence un comportement de mimetisme dans les decisions de production jointe de bois et d'amenites des proprietaires forestiers prives. Enfin, nous analysons les arbitrages inter-temporels realises par les proprietaires entre amenites non-bois et revenu de la vente de bois en prenant en compte explicitement les anticipations de prix et de croissance. Nous evaluons a 23e par an la valeur que les proprietaires de notre echantillon accordent a 1m3/ha de bois supplementaire laisse sur pied par rapport au niveau de stock des proprietaires industriels afin d'avoir des amenites plus importantes.Un des enjeux de ce travail est d? offrir des pistes pour mobiliser la ressource forestiere ne faisant pas l'objet d'une offre, faute d'implication des proprietaires prives, soit par manque de connaissance ou d'interet pour leur foret, soit parce que d'autres aspects sont privilegies (services d'amenites non-bois par exemple). Dans cette these, nous montrons que les effets de mimetisme et d'entrainement social (effets sociaux) peuvent etre utilises pour amener les proprietaires forestiers a produire plus de bois. Nous montrons egalement, qu'une hausse du prix du bois ou la mise en place d'une taxepeut favoriser la prise de la decision de coupe de bois et augmenter l'intensite de la recolte.
SFB 823 Efficient computation of Bayesian optimal discriminating designs

An efficient algorithm for the determination of Bayesian optimal discriminating designs for competing regression models is developed, where the main focus is on models with general distributional assumptions beyond the “classical” case of normally distributed homoscedastic errors. For this purpose we consider a Bayesian version of the KullbackLeibler (KL) optimality criterion introduced by López-Fidalgo et al. (2007). Discretizing the prior distribution leads to local KL-optimal discriminating design problems for a large number of competing models. All currently available methods either require a large computation time or fail to calculate the optimal discriminating design, because they can only deal efficiently with a few model comparisons. In this paper we develop a new algorithm for the determination of Bayesian optimal discriminating designs with respect to the Kullback-Leibler criterion. It is demonstrated that the new algorithm is able to calculate the optimal discriminating designs with reasonable accuracy and computational time in situations where all currently available procedures are either slow or fail. Keyword and Phrases: Design of experiment; Bayesian optimal design; model discrimination; gradient methods; model uncertainty; Kullback-Leibler distance
The Edible red Alga, Gracilaria verrucosa, Inhibits Lipid Accumulation and ROS Production, but Improves Glucose Uptake in 3T3‐L1 Cells

Gracilaria verrucosa is a red alga that is widely distributed in seaside areas of many countries. We examined the effect of G. verrucosa extract on adipogenesis, reactive oxygen species (ROS) production, and glucose uptake in 3T3‐L1 cells. Oil red O staining and a nitroblue tetrazolium assay showed that G. verrucosa extract inhibited lipid accumulation and ROS production, respectively. mRNA levels of adipogenic transcription factors, peroxisome proliferator‐activated receptor gamma and CCAAT/enhancer‐binding protein alpha, as well as of their target gene, adipocyte protein 2, were reduced upon treatment with G. verrucosa extract. However, G. verrucosa extract increased glucose uptake, glucose transporter‐4 expression, and AMP‐activated protein kinaseα (AMPKα) phosphorylation compared to the control. Our results suggest that the anti‐adipogenic and insulin‐sensitive effects of G. verrucosa extract can be recapitulated to activation of AMPKα. Copyright © 2012 John Wiley & Sons, Ltd.
Perceptual learning in detoxified alcoholic men: contributions from explicit memory, executive function, and age.

BACKGROUND Visuospatial and visuoperceptual deficits have consistently been observed in detoxified alcoholics; however, the severity of impairment varies with test and task type. Identifying the component processes and factors that underlie a particular deficit may reveal why some visuospatial and visuoperceptual tasks are more compromised than others and may lead to the specification of neural systems that are particularly vulnerable in alcoholism. METHODS We examined visuoperception and perceptual learning with a picture fragment identification task in 51 recently detoxified nonamnesic alcoholic men (aged 29-66 years) compared with 63 normal control men (aged 21-70 years). Executive function and explicit declarative memory were also assessed. RESULTS Despite deficits in the primary components of visuoperception and explicit memory for visuospatial stimuli, the alcoholics showed normal perceptual learning. Although the alcoholics and controls performed at comparable levels on the perceptual learning task, multiple regression analyses indicated that the factors accounting for perceptual learning variance differed between and within groups. Visuoperceptual abilities consistently predicted perceptual learning in the control subjects but not the alcoholic subjects. Explicit memory contributed to perceptual learning performance in both the alcoholic and control groups. Frontal executive ability consistently predicted perceptual learning in the alcoholic subjects, but it had predictive ability only in the control subjects as time elapsed. Age was significantly correlated with perceptual learning performance in both groups. Lifetime alcohol consumption, but not alcoholism duration, was an independent predictor of 1-hr perceptual learning. CONCLUSIONS These correlational analyses suggest that controls invoke basic visuospatial processes to perform a perceptual learning task, whereas alcoholics invoke higher-order cognitive processes (i.e., frontal executive systems) to perform the same task at normal levels. Use of more demanding cognitive systems by the alcoholics may be less efficient and more costly to processing capacity than those invoked by controls.
X-Band Waveguide Filtering Antenna Array With Nonuniform Feed Structure

This paper proposes a novel design approach for a filtering antenna, which contains an array of 4 by 2 waveguide aperture radiation elements. Coupling matrix theory is introduced in this paper to synthesize the multiple coupled-resonators circuit. Unequal amplitude excitation is applied to the <inline-formula> <tex-math notation="LaTeX">$4 \times 2$ </tex-math></inline-formula> elements so as to obtain a low sidelobe level. To demonstrate the concept, an X-band antenna array is designed and fabricated using a three-layer waveguide structure. Measured results show that the filtering antenna array can achieve a gain of more than 15.58 dBi and a radiation efficiency of higher than 90% over the passband (9.91–10.1 GHz). The sidelobe level is −18.3 dB in the <inline-formula> <tex-math notation="LaTeX">${H}$ </tex-math></inline-formula>-plane and −21.1 dB in the <inline-formula> <tex-math notation="LaTeX">${E}$ </tex-math></inline-formula>-plane.
Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer

Introduction: Despite significant improvements in diagnosis and therapy over the past 20 years, breast cancer remains a worldwide public health issue. In particular, triple negative breast cancer (TNBC), a subset of very aggressive breast tumors, is associated with a poor prognosis and has very few efficient therapeutic options. The ectonucleotidase CD73 has recently emerged as a promising new target for TNBC in preclinical models. Pharmacological targeting of CD73 and downstream adenosine A2A/A2B receptor signaling is currently an active field of research that could lead to the development of new cancer therapeutics, including options against TNBC. Areas covered: This article reviews the basic structural and molecular features of CD73 and its role in the development of cancer, with a particular focus on CD73's role in the biology of TNBC. Expert opinion: It was recently demonstrated that CD73 expression in TNBC is associated with worse clinical outcomes and increased resistance to anthracycline chemotherapy. Targeted blockade of the CD73/A2A axis has been shown to impair various aspects of tumorigenesis and displays synergism with other anti-cancer treatments in preclinical studies. Hence, we strongly argue for the development of CD73 inhibitors and for the repositioning of A2A antagonists in cancer.
Viral DNA tethering domains complement replication-defective mutations in the p12 protein of MuLV Gag

The p12 protein of murine leukemia virus (MuLV) group-specific antigen (Gag) is associated with the preintegration complex, and mutants of p12 (PM14) show defects in nuclear entry or retention. Here we show that p12 proteins engineered to encode peptide sequences derived from known viral tethering proteins can direct chromatin binding during the early phase of viral replication and rescue a lethal p12-PM14 mutant. Peptides studied included segments of Kaposi sarcoma herpesvirus latency-associated nuclear antigen (LANA)1–23, human papillomavirus 8 E2, and prototype foamy virus chromatin-binding sequences. Amino acid substitutions in Kaposi sarcoma herpesvirus LANA and prototype foamy virus chromatin-binding sequences that blocked nucleosome association failed to rescue MuLV p12-PM14. Rescue by a larger LANA peptide, LANA1–32, required second-site mutations that are predicted to reduce peptide binding affinity to chromosomes, suggesting that excessively high binding affinity interfered with Gag/p12 function. This is supported by confocal microscopy of chimeric p12-GFP fusion constructs showing the reverted proteins had weaker association to condensed mitotic chromosomes. Analysis of the integration-site selection of these chimeric viruses showed no significant change in integration profile compared with wild-type MuLV, suggesting release of the tethered p12 post mitosis, before viral integration.
Comparative Research Design: A Guide for the Clinical Nurse Specialist

C linically relevant research is needed to advance the science of nursing and provide patients with the best options possible to enhance their health and well-being. To minimize the gap between the discovery of new knowledge and the implementation and translation of this knowledge into changes in patient care requires that the clinical nurse specialist become involved in asking the questions that really matter to patients and nurses. While research is conducted by various individuals (physicians pharmacists, academics), the clinical nurse specialist is in a unique position to identify the problems most in need of solutions today. Comparative research designs are most often used when asking questions about the cost-effectiveness or efficacy of treatments. The results of comparative studies help the clinical nurse specialist (CNS) make decisions and recommendations for patient care. Comparative studies can be experimental or nonexperimental. Experimental designs are usedwhen it is feasible and ethical to assign individuals to different treatment conditions. Nonexperimental designs are used when it is not ethical or feasible to assign individuals to treatment groups, but the groups may occur naturally (for example, gender). Although both designs are equally important, this article focuses on the experimental design process and provides guidelines for designing and conducting a comparative study that will maximize the validity of the findings and provide the CNS with the opportunity to contribute to the knowledge of the profession.
DISTRIBUTION AND TISSUE SPECIFICITY OF GLUTAMATE DECARBOXYLASE (EC4.1.1.15) 1

Abstract— The activity of L–glutamate decarboxylase (EC 4.1.1.15) (GAD) in various mouse tissues was determined by five different methods, namely, the radiometric CO2 method, column separation, electro–phoretic separation, the filtration method, and amino acid analysis. Results from the latter four methods agreed well, showing that brain had the highest activity, 4.27 nmol/min/mg protein (100%), followed by heart (7.4%), kidney (6.3%) and liver (1.5%). Measurement of brain GAD using the radiometric CO2 assay method agreed with the other techniques. However, in heart, kidney, and liver, the GAD activities measured by the CO2 method were about 3–4 times higher than those obtained by the GABA method, suggesting that the CO2 method does not give a valid measurement of GAD activity in a crude non–neural tissue preparation. GAD activity also was detected in adrenal gland but not in pituitary, stomach, testis, muscle, uterus, lung, salivary gland, or spleen. GAD from brain, spinal cord, heart, kidney and liver were further compared by double immunodiffusion, enzyme inhibition by antibody, and microcomplement fixation using antibody against GAD purified from mouse brain. GAD from brain and spinal cord appear to be identical as judged from the following results: the immunoprecipitin bands fused together without a spur; the enzyme activity was inhibited by anti–GAD to the same extent; and the microcomplement fixation curves were similar in both the shape of the curve and the extent of fixation. No crossreactivity was observed between GAD from heart, kidney or liver and antibody against brain GAD in all the immunochemical tests described above, suggesting that GAD in non–neural tissues is different from that in brain and spinal cord.
Autopsy: The Dying Diagnostic

Angus Turnbull1* and Michael Osborn2 1Imperial College School of Medicine, Sir Alexander Fleming Building, South Kensington Campus, London, UK 2Department of Cellular Pathology, Imperial College NHS Healthcare Trust, London, UK *Corresponding author: Angus Turnbull, Imperial College School of Medicine, Sir Alexander Fleming Building, South Kensington Campus, London, SW7 2AZ, UK, Tel: 44735650914; E-mail: ajt108@imperial.ac. uk
Accurate image reconstruction in circular cone-beam computed tomography by total variation minimization: a preliminary investigation

The total variation (TV) minimization image reconstruction algorithm for inverting the divergent-beam X-ray transform is applied to image reconstruction in circular cone-beam computed tomography (CT). Reconstructions for the disk phantom are shown and compared with that of projection onto convex sets (POCS). The preliminary results appear to show that TV-minimization yields accurate image reconstructions that are robust against data inconsistencies due to noise or mismatch in the system matrix.
Color-Critical Graphs on a Fixed Surface

Let S be an orientable surface other than the sphere and letkbe a natural number. Then there are infinitely manyk-color-critical graphs onSif and only if 3? k? 5. In particular, ifk? 5, then there exists a polynomially bounded algorithm for deciding if a graph onScan bek-colored. We extend this to the case where a subgraph of fixed cardinality is precolored. We also establish a corresponding list-color theorem.
THE HYDRODYNAMIC STABILITY OF INVISCID FLOW BETWEEN COAXIAL CYLINDERS.

where R1 and R2 are, respectively, the radii of the inner and the outer cylinders. The presence of viscosity inhibits the onset of instability and condition (3) must be violated by a certain determinate extent before instability can arise. The extent of this inhibition has been considered by a number of authors since G. I. Taylor first investigated the problem.1 The equations of viscous flow allow stationary solutions besides those given by (2). Thus a constant transverse pressure gradient, bp/r6O, leads to a superposition of a Poiseuille type of flow on the distribution (2). The stability of such flows has been considered by Dean2, Reid3, and DiPrima,4 among others. Another type of generalization is the superposition of an axial flow over (2). The stability of such non-Couette flows has been considered by Goldstein,5 but Goldstein's treatment was of a preliminary character.6 In undertaking a more comprehensive treatment of the latter problem, it became clear that the corresponding problem in inviscid flow has not been considered. The present paper is devoted to its consideration. 2. By writing the equations of inviscid flow in cylindrical polar-coordinates, (r, 0, z), we can directly verify that