Miracle-dz/UniFAR-FTUs huggingface dataset:
Genetic diversity of mitochondrial cytochrome b and control region in Eothenomys miletus of Jianchuan,Yunnan Province

To investigate the genetic diversity of Orient voles( Eothenomys miletus),DNA sequence variations in the mitochondrial cytochrome b gene and control region of the 30 individuals from Jianchuan,Yunnan Province were measured. For cytochrome b gene( Cyt b),16 nucleotide sites were variable( 1. 40% in the full sequences),including 3 transitions and 0 transversions among 1140 base pairs( bp),the nucleotide diversity( Pi) was 0. 0296,the haplotypes diversity( Hd) was 0. 876 ± 0. 041,and 12 haplotypes were identified in the 30 samples. For control region( D-loop),987 base pairs were examined,28 nucleotide sites were variable( 2. 84% in the full sequences),including 5 transitions and 1 transversions,the nucleotide diversity was 0. 0055,the haplotypes diversity was 0. 924 ± 0. 029,16 haplotypes were identified in the 30 samples. Based on control region,the genetic diversity of Eothenomys was less than Clethrionomys,so the Eothenomys could be younger than Clethrionomys,and the genetic diversity may be related with the distribution ranges and ecological factors.
A New Algorithm for Storing and Migrating Data Modelled by Graphs

NoSQL databases have moved from theoretical solutions to exceed relational databases limits to a practical and indisputable application for storing and manipulation big data. In term of variety, NoSQL databases store heterogeneous data without being obliged to respect a predefined schema such as the case of relational and object-relational databases. NoSQL solutions surpass the traditional databases in storage capacity; we consider MongoDB for example, which is a document-oriented database capable of storing unlimited number of documents with a maximal size of 32TB depending on the machine that runs the database and also the operating system. Also, in term of velocity, many researches compared the execution time of different transactions and proved that NoSQL databases are the perfect solution for real-time applications. This paper presents an algorithm to store data modeled by graphs as NoSQL documents, the purpose of this study is to exploit the high amount of data stored in SQL databases and to make such data usable by recent clustering algorithms and other data science tools. This study links relational data to document datastores by defining an effective algorithm for reading relational data, modelling those data as graphs and storing those data as NoSQL documents.
Essential oils in prevention of Dental Caries - An In-Vitro study

Since the middle ages, essential oils have been widely used for bactericidal, virucidal, fungicidal, antiparasitical, insecticidal, medicinal and cosmetic applications, especially nowadays in pharmaceutical, sanitary, cosmetic, and agricultural and food industries. Because of the mode of extraction, mostly by distillation from aromatic plants, they contain a variety of volatile molecules such as terpenes and terpenoids, phenol-derived aromatic components and aliphatic components. So the aim of the present study was to evaluate the role of essential oils Wintergreen and Rosemary oil in prevention of dental caries worldwide. Their curative effect has been known since antiquity. It is based on a variety of pharmacological properties which are specific for each plant species. Antibacterial activity of the two essential oils, Wintergreen and Rosemary oil were screened against Streptococcus mutans, using disc diffusion technique. The results of this study showed that the extracts at different concentrations exhibited anti bacterial activity against the bacterial species tested.
MORPHOLOGICAL VARIATION AND GENETIC DIVERSITY IN ANEUROLEPIDIUM CHINENSE

The anatomy of vegetative plants Aneurolepidium chinense sourced from seven populations growing under differing soil conditions was examined using optical microscopy and SEM.The genetic diversity of these populations was also studied,and the correlation between genetic diversity and soil factors was analyzed.The results indicated that:1) The seven populations were similar to saline-alkali soil type populations in their root structure, and to chernozem soil type populations in their stem structure.The structure of leaves was a transition type between that typical of chernozem soil and that of saline-alkali soil.2) Genetic polymorphism of A. chinense populations was high.Amplification of 53 random primers revealed 365 amplified fragments of which 303 (83.01%) were polymorphic and 121 (33.21%) unique.3) The genetic distance among the seven populations varied from 0.2349 to 0.6166 and cluster analysis identified three distinct groups.4) The average number of polymorphic loci was negatively correlated with soil organic matter and total nitrogen content.The average number of unique fragments correlated negatively with soil Mg and Ca concentrations,while values of genetic distance variation was correlated positively with conductivity and aqueous Na concentration.
Use of cotton plant byproducts as a source of fiber in feedlot diets

Cotton fibre co-products available in northern Argentina are a source of effective fiber to replace high cost roughage (e.i., alfalfa hay or silage or grasses) in finishing diets. This experiment was conducted to evaluate the effect of replacing roughage sources (alfalfa hay) by cotton plant byproduct (SPA) on average daily gain (ADG), dry matter intake (DMI) and feed efficiency (DMI/ADG) in feedlot diets. One hundred and four (220 ± 4 kg LW) were assigned to 12 pens (8 or 9 animals/per pen) for 68 days on feed. The experiment was divided in two feeding periods: adaptation (days 0 to 19) and finishing (days 20 to 68). Treatments consisted of replacing the roughage portion of the diet (alfalfa hay; 12.9% CP, 65.5% NDF) by SPA (7.2% CP, 71.4% NDF): 100% alfalfa (SPA0); 66% alfalfa: 33% SPA (SPA33); 33% alfalfa: 66% SPA (SPA67); and 100% SPA (SPA100). Initial (day 0; P = 0.92), adaptation (day 19; P = 0.26) and final (day 68; P = 0.37) average live weight did not significantly differ among treatments. Moreover, ADG (P > 0.43), DMI (P > 0.23) and DMI/ADG (P > 0.50) were not affected by treatments for both feeding periods. Results show that total or partial replacement of alfalfa roughage by SPA in high concentrate diets (>89%) do not adversely affect live weight gain and feed efficiency.
Cancer and the tumor microenvironment

Formerly referred to as a group of altered cells in proliferation, today cancer is better understood as a microenvironment, in which the interactions between the cellular and molecular elements are determinative in tumor progression. As a result, the comprehension of a neoplasic event gains increasing complexity. The dynamics of the tumor cells are now analyzed as part of a true tumoral tissue, subject to conditions of vascularization, oxygenation, interstitial pressure and tissue necrosis, which influence tumor kinetics. New components of this tumoral niche and their respective actions are being identified. Among these constituents are the elements of the immune system which, as a series of experiments have shown, are involved in the aspect of immunosurveillance, as negative selective pressure, as well as in mechanisms of tumor progression. This review will analyze neoplasia as a tumor microenvironment, focusing on immunological participation and on tumor kinetics, and exposing the main ideas and discoveries that created and are improving the concept of cancer.
Effects of Red and Blue Light on the Cardiac Autonomic Nervous System

Purpose: Light is an important environmental stimulus influencing everyday life. However, information about the impact of coloured light on the autonomic nervous system (ANS) is sparse. In general, red light (RL) is thought to act as an adrenergic trigger, while there is evidence that blue light (BL) induces parasympathetic activation. This is a pilot study to find out, if RL and/or BL affects heart rate variability (HRV). Methods: Participants were randomly exposed first to neutral light (NL) and then to RL and BL for 120 minutes in a special light cabin. During each test run, HRV measurements were performed using both wrist training computers and Holter-ECGs. Furthermore, heart rate, arrhythmias and blood pressure were analysed. All parameters were measured during neutral and repeated during RL or BL in 10 supraventricular tachycardia patients, in 10 patients with heart failure and 10 athletes. Results: During exposure to both RL and BL an increase of blood pressure, improvements of several HRV parameters, but no significant change of heart rate was observed. Neither RL nor BL influenced the occurrence of ectopic beats in Holter ECGs. The most prominent improvement of HRV was found in athletes, whereas increase in blood pressure were comparable between all three groups. Conclusion: RL and BL influence the cardiac ANS. Since no differences were found between different light scenarios, the changes can not solely be attributed to the two-sided model of sympathetic and parasympathetic effects of ANS. However, RL and BL could potentially be used therapeutically to influence HRV in athletes.
Malware classification using XGboost-Gradient Boosted Decision Tree

Article history: Received: 31 July, 2020 Accepted: 06 September, 2020 Online: 26 September, 2020 In this industry 4.0 and digital era, we are more dependent on the use of communication and various transaction such as financial, exchange of information by various means. These transaction needs to be secure. Differentiation between the use of benign and malware is one way to make these transactions secure. We propose in this work a malware classification scheme that constructs a model using low-end computing resources and a very large balanced dataset for malware. To our knowledge, and search the complete dataset is used the first time with the XGBoost GBDT machine learning technique to build a classifier using low-end computing resources. The model is optimized for efficiency with the removal of noisy features by a reduction in features sets of the dataset by domain expertise in malware detection and feature importance functionality of XGboost and hyperparameter tuning. The model can be trained in low computation resources at less time in 1315 seconds with a reduction in feature set without affecting the performance for classification. The model gives improved performance for accuracy with the tuning of the hyperparameter and achieve higher accuracy of 98.5 and on par AUC of . 9989.
Virulence factors of Candida albicans

Candida is one of the main causes of invasive fungal infections,with Candida albicans as the most common species.Invasive candidiasis often occurs in patients suffering from immunodeficiency,receiving organ transplantation or interventional therapy,and those administrating broad-spectrum antibiotics or glucocorticoids.Candida albicans virulence factors,including phenotypic switching,adhesins,hydrolytic enzymes,hemolysis factors,are closely related to its pathogenicity.Phenotypic switching can help Candida albicans to adapt to host tissue environment,adhesins can facilitate tissue recognition and colonization,hydrolytic enzymes can destroy mucosal integrity and enhance virulence,and hemolysis factors can help to obtain nutrients for survival and reproduction.To further clarify the relationship between virulence factors and pathogenicity of Candida albicans may provide novel ideas for the prevention and treatment of candidiasis. Key words: Candida albicans; Virulence factors; Opportunistic infections
Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells

The Mus81–Eme1 complex is a structure-specific endonuclease that preferentially cleaves nicked Holliday junctions, 3 0 -flap structures and aberrant replication fork structures. Mus81 (cid:2) / (cid:2) mice have been shown to exhibit spontaneous chromosomal aberrations and, in one of two models, a predisposition to cancers. The molecular mechanisms underlying its role in chromosome integrity, however, are largely unknown. To clarify the role of Mus81 in human cells, we deleted the gene in the human colon cancer cell line HCT116 by gene targeting. Here we demonstrate that Mus81 confers resistance to DNA crosslinking agents and slight resistance to other DNA-damaging agents. Mus81 deficiency spontaneously promotes chromosome damage such as breaks and activates the intra-S-phase checkpoint through the ATM-Chk1/Chk2 pathways. Furthermore, Mus81 deficiency activates the G 2 /M checkpoint through the ATM-Chk2 pathway and promotes DNA rereplication. Increased rereplication is reversed by the ectopic expression of Cdk1. Haploinsufficiency of Mus81orEme1also
Differences in trace element profiles of three subspecies of Silene parnassica (Caryophyllaceae) growing on ophiolitic substrate

The aim of the present study was to compare trace element profiles and the differences in uptake and translocation of trace elements in plants from five populations (three from Greece and two from Serbia) belonging to three subspecies of Silene parnassica Boiss. & Sprun. growing on ophiolitic substrates. For comparison of the subspecies, bioconcentration and translocation factors were used, as well as Spearman’s rank correlation coefficients for concentrations of elements in root and shoot samples. Chemical characteristics of the soil samples (pH, organic C, P2O5, K2O, Ca, Fe, Mg, Mn, Ni, Zn, Cu, Cr, Co, Cd and Pb) and plant samples (P2O5, K2O, Ca, Fe, Mg, Mn, Ni, Zn, Cu, Cr, Co, Cd and Pb) were determined, as well as bioconcentration and translocation factors and correlation matrices. All the three subspecies acted as strong Ni accumulators, with equal concentrations of Ni in roots and shoots, the values being several times higher than 100 mg kg–1, exceeding concentrations of available Ni in the soil. Concentrations of Cu and Cr in the aboveground plant tissues in samples from three localities were several times higher than expected, even for plants growing on metalliferous soils, exceeding, by multiple times, the available concentrations in the soil samples.
Influence of Oxygen on Proline Utilization During the Wine Fermentation

In order to overcome sluggish or stuck fermentations, it may be necessary to utilize oxygen and yeast-utilizable nitrogen sources found in some yeast foods. Government regulations in the US preclude the use of large amounts of yeast foods — even those derived from yeast or proteins often employed as food ingredients. The present work describes the conditions under which proline, an amino acid naturally present in high concentrations in musts, can be utilized fully as a source of nitrogen. Oxygen is required for proline degradation; it is also a requirement to ensure sufficient yeast growth and to avoid sluggish fermentations.
In vitro Antioxidant Properties of Forsythia suspense Leaves Flavonoids

To study the in vitro antioxidant activity of the Forsythia suspense leaves flavonoids(FLF),the scavenging effect of FLF on hydroxyl radicals(·OH) was studied by salicylic acid method,and self-oxidation inhibition was studied using the pyrogallol.The contents of MDA in 4 organs,and in mitochondria and microsome of liver were measured by TBA assay.The extent of erythrocatalysis and the swelling extent of mitochondria of liver were detected by spectrophotometric methods.The result showed that FLF had the·OH and O-2· scavenging activity.It could inhibit the generation of MDA,the swelling of mitochondria,and the hemolysis of red blood cells.The conclusion was drawn that FLF have the antioxidant activity.
Isolation and Identification of a Jiangxiang-producing Bacillus Strain from Jiangxiang Daqu

11 Bacillus strains were isolated from Jiangxiang Daqu by plate method. Then liquid fermentation of all 11 strains was carried out in bran culture medium at 55 ℃, and a Jiangxiang-producing strain MT6 was further screened out. The strain MT6 was identified as Bacillus sp.through 16S rDNA gene phylogenetic analysis. And the strain could be used for the preparation of bioaugmentation bacterial product to enhance the flavor and the quality of high-temperature Daqu.
Taxonomy, location of origin and health status of proboscideans from Western Canada investigated using stable isotope analysis

We investigated the application of stable isotope analysis of proboscidean remains (collagen in bone/dentin/cementum and structural carbonate in enamel bioapatite) for genus‐level identification of isolated specimens, assessment of geographical origins, and testing for nutritional stress. Mammoths (Mammuthus sp.) tended to have higher δ15Ncol and lower δ13Ccol than mastodons (Mammut americanum), but differences were not significant in every location. Determining the genus of isolated specimens may be possible for locations and time periods with good isotopic baselines, but environmental changes can confound interpretations. For example, an Alberta proboscidean with a δ15Ncol of +1.4‰ (characteristic of mastodons) ultimately proved to be a mammoth. Its surprisingly low nitrogen isotope composition is attributable to the recently deglaciated environment it inhabited. We provided a baseline for isotopic assessment of geographical origins of isolated proboscideans in Western Canada. Bioapatite δ13Csc and δ18Osc can be used to distinguish specimens from Alberta, Klondike, Old Crow, Herschel Island and further south (e.g. Arizona, Great Lakes). Finally, we found that an Alberta mammoth with morphological evidence of nutritional stress experienced a change in diet, environment or physiology before death, but its isotopic compositions did not suggest a link to hypothesized starvation (catabolism of proteins or reliance on lipids).
Partridge Berry: Simple Beauty Belies Complexity

uperficially, plants seem so simple. Rooted in place, they do not move around. And while plant growth is a dynamic process, without time-lapse photography, growth events are so imperceptibly slow that, to us impatient humans, plants seem both immobile and static. Nevertheless, there is a lot going on inside the plant body, and this is especially true for the events of reproduction that play out inside flowers and fruits. As one of my students recently commented, “I used to think it was just a matter of pollen plus stigma and, presto-change-o, seeds happen. ” That student, I hope, learned otherwise, as will anyone else who takes the time to study the biology of flowers in detail.
Study of long-term effectiveness of the hyperbaric oxygen therapy in neonatal hypoxic-ischemic encephalopathy

目的 研究高压氧(HBO)对新生儿缺氧缺血性脑病(HIE)远期疗效的影响程度. 方法将同期住院的60例HIE患儿随机分为HBO组与对照组各30例,两组在采取完全相同常规药物治疗的基础上,HBO组接受HBO治疗,1次/d,共10 d. 治疗后5～7年对HBO组28例(失访2例)、对照组26例(死亡1例、失访3例)进行集中测查,采用龚耀先主持修订的中国韦氏幼儿智力量表(C-WYCSI)进行智力测验,并做详细的体格、神经系统、头颅CT、x线胸片、鼓膜、视网膜及视听检查. 结果 HBO组患儿后遗症的发生率(2/28)低于对照组(8/26),差异有显著性,x2=4.99,P＜0.05;HBO组总智商(FIQ)92.89±15.78、言语智商(VIQ)93.99±16.91、操作智商(PIQ)89.18±15. 02均高于对照组(FIQ82.27±1 9.80、VIQ83.12±21.25、PIQ78.96土21.45),差异有显著性,t值≥2.10,P＜0.05;HBO组患儿智力缺损及边界状态的发生率(4/28)明显低于对照组(9/26),差异有显著性,x2=4.46,P＜0.05. 两组患儿体格发育各项指标均在正常范围. 结论 HIE患儿在常规药物治疗基础上,配合HBO治疗效果肯定,能够明显改善远期预后,提高智商水平,降低致残率. 未发现肺发育不良及晶体后纤维增生等副作用。
Creation of New Soybean SCN4-Resistant Lines

Soybean cyst nematode(SCN)is one of the major soybean diseases.The most economic and efficient measure is to develop disease-resistant varieties,and there is no varieties immune or high resistant to SCN4 in Huang-huai region present.Hartwig and Jin 1261 etc.were crossed and offspring were identified through yield and resistance.Seven yellow varieties were selected because they possess high yield and good agronomic traits and high resistance or immunity to SCN1and 4,which can be used as parent to breed high resistant varieties.
Association between Discharge Pharmacist Counselling Techniques and Hospital Readmission Rate

The Indian Health Services counseling technique has been used for decades, but no study has assessed its effect on patient health outcome. Objective: We evaluated the impact of a new discharge counseling technique on patients’ readmission rate and on identifying medication discrepancies during discharge. Methods: A retrospective investigational study was conducted to compare the 30 days readmission rate among patients subjected to the new counseling method with those of the standard methods (primary objective). Data for 30-day readmission rate were collected from patients’ medical records and the hospital electronic system. The secondary objective was to evaluate the frequency and types of drug-related problems detected at the time of discharge among both groups. All patients who were counseled using the new counseling technique during December 2011 to January 2012 and the standard techniques during October and November 2011 were included. Results: We identified 191 patients counseled using the standard technique and 233 patients counseled using the new technique. The readmission rate was lower by approximately 34% for the new counseling technique (15.8%) compared with those subjected to the standard one (24.1%; P =0.034; OR: 1.681; 95% confidence interval (CI), 1.037-2.724). The new technique helped the pharmacists to identify the discrepancies more frequently (20.6%) compared with the standard technique (5.2%; P<0.001). There were statistically significant differences regarding the type of diagnosis, gender and number of medication used between the two counseling technique. Multiple logistic regression models identified that type of counseling, and type of diagnosis was significant independent factor associated with readmission within 30 days after discharge. Conclusion: Our study showed that the new discharge counseling technique was associated with a lower readmission rate and improved detection of identified discrepancies 4 times more than the standard technique for identified high-risk adult and pediatric patients. Larger-scale prospective studies are needed to confirm this finding.
Steady Convective Motion in a Horizontal Layer of Fluid Heated Uniformly from Above and Cooled Non‐uniformly from Below

A gravitationally stable fluid layer is heated non-uniformly (sinusoidally) at the bottom (or top) and a thermal convection regime is established. Examples are worked out for cases (i) without rotation (ii) with uniform rotation, and (iii) with non-uniform rotation (beta-plane). DOI: 10.1111/j.2153-3490.1957. tb01896.x
The massless spectrum of heterotic compactifications

We discuss the four‐dimensional massless spectrum of supersymmetric Minkowski compactifications of ten‐dimensional heterotic supergravity, including the anomaly cancelation condition. This can be calculated from restrictions arising from F‐term conditions in a four dimensional effective theory. The results agree with computations of the infinitesimal moduli space recently performed from a ten‐dimensional perspective. The paper is based on a talk given by Eirik Eik Svanes in Leuven for the workshop on 'The String Theory Universe'.