Miracle-dz/UniFAR-FTUs huggingface dataset:
Determinants of software quality in COTS products: an exploratory study

More recently, the emphasis has shifted to the ability of vendors in providing high quality rather than low cost software products and services from India. The present research is to explore key organisational and socio-technical factors which influence software quality, through case study of a leading midsize Indian software firm, which offers consulting and software services globally to some of the well known companies, specifically in the context of COTS (ERP) environment. Our research reveals that the factors such as requirements uncertainty, process maturity, communication and control, knowledge transfer and integration, trained personnel and infrastructure facilities have significant impact on achieving product quality. Based on our research, we suggest organisational factors have greater influence on achieving software quality. We present the implications for practice and directions for further research.
The Resolution Revolution

Advances in detector technology and image processing are yielding high-resolution electron cryo-microscopy structures of biomolecules. [Also see Report by Amunts et al.] Precise knowledge of the structure of macromolecules in the cell is essential for understanding how they function. Structures of large macromolecules can now be obtained at near-atomic resolution by averaging thousands of electron microscope images recorded before radiation damage accumulates. This is what Amunts et al. have done in their research article on page 1485 of this issue (1), reporting the structure of the large subunit of the mitochondrial ribosome at 3.2 Å resolution by electron cryo-microscopy (cryo-EM). Together with other recent high-resolution cryo-EM structures (2–4) (see the figure), this achievement heralds the beginning of a new era in molecular biology, where structures at near-atomic resolution are no longer the prerogative of x-ray crystallography or nuclear magnetic resonance (NMR) spectroscopy.
Behavioral and electrophysiologic binaural processing in persons with symmetric hearing loss.

BACKGROUND Binaural hearing improves our ability to understand speech and to localize sounds. Hearing loss can interfere with binaural cues, and despite the success of amplification, ∼25% of people with bilateral hearing loss fit with two hearing aids choose to wear only one (e.g., Brooks and Bulmer, 1981). One explanation is reduced binaural processing, which occurs when the signal presented to one ear interferes with the perception of the signal presented to the other ear (e.g., Jerger et al, 1993). Typical clinical measures, however, are insensitive to binaural processing deficits. PURPOSE The purpose of this study was to determine the extent to which behavioral measures of binaural performance were related to electrophysiological measures of binaural processing in subjects with symmetrical pure-tone sensitivity. RESEARCH DESIGN The relationship between middle latency responses (MLRs) and behavioral performance on binaural listening tasks was assessed by Spearman's rho correlation analyses. Separate repeated measures analyses of variance (RMANOVAs) were performed for MLR latency and MLR amplitude. STUDY SAMPLE Nineteen subjects were recruited for the present study based on a clinical presentation of symmetrical pure-tone sensitivity with asymmetrical performance on a word-recognition in noise test. This subpopulation of patients included both subjects with and subjects without hearing loss. DATA COLLECTION AND ANALYSIS Monaural and binaural auditory processing was measured behaviorally and electrophysiologically in right-handed subjects. The behavioral tests included the Words-in-Noise test (WIN), the dichotic digits test (DDT), and the 500 Hz masking level difference (MLD). Electrophysiologic responses were measured by the binaural interaction component (BIC) of the MLR. The electrophysiological responses were analyzed to examine the effects of peak (Na, Pa, and Nb) and condition (monaural left, monaural right, binaural, and BIC) on MLR amplitude and latency. RESULTS Significant correlations were found among electrophysiological measures of binaural hearing and behavioral tests of binaural hearing. A strong correlation between the MLD and the binaural Na-Pa amplitude was found (r = .816). CONCLUSIONS The behavioral and electrophysiological measures used in the present study clearly showed evidence of reduced binaural processing in ∼10 of the subjects in the present study who had symmetrical pure-tone sensitivity. These results underscore the importance of understanding binaural auditory processing and how these measures may or may not identify functional auditory problems.
Healthy Rural Tourism with Good Management in Penglipuran Bali – Indonesia

The involvement of the rural tourism citizens in developing, maintaining and managing the village is the key to the success of a rural tourism. Rural citizens are the main drivers of the rural tourism activities, where local people are direct owners of tourism resources that visitors can enjoy. A commitment, which is successfully built from generation to generation, makes Penglipuran a rural tourism with a clean and healthy environment. The trust given to one resident manager can maintain the conservation of bamboo forests. The “Sapta Pesona” have been implemented and practiced. The management of the bamboo forest conservation, the commitment from both rural citizens and visitors to not smoking and their collaboration to manage the village waste and aware of the cleanliness of the environment are challenging practices since they require exceptional efforts to realize. However, when the initiative comes from the rural citizens, then it will be easier to execute these commitments.
Speckle imaging in astronomy

This article discusses current research in speckle interferometry and speckle imaging in astronomy. These techniques continue to have a significant impact on problems such as stellar formation, stellar masses, and planetary astronomy. In a regime of increasingly sophisticated and impressive instrumentation designed for high‐resolution imaging, there is still an important role for the single‐aperture passive technique of speckle imaging.
Avian reticuloendotheliosis virus-transformed lymphoid cells contain multiple pp59v-rel complexes

The v-rel oncogene of avian reticuloendotheliosis virus type T (REV-T) encodes a 59-kilodalton (kDa) phosphoprotein located principally in the cytosol of transformed lymphoid cells. All of the detectable pp59v-rel was present in high-molecular-weight complexes containing at least five cellular proteins (p124, p115, p75c-rel, p70hsc, and pp40). Antiserum was developed against the 40-kDa protein, the most abundant cellular protein associated with the complex. The 40-kDa phosphoprotein was complexed with pp59v-rel in REV-T-transformed lymphoid cell lines arrested at different stages of B-cell development as well as in lymphoid tumor cells and in fibrosarcomas. The half-life (8 h) of pp40 in REV-T-transformed lymphoid cells was the same as that of pp59v-rel. Antiserum against pp40 permitted the identification of two pp59v-rel complexes. The most abundant cytoplasmic complex contained approximately 75% of the pp59v-rel and all of the detectable pp40 in REV-T-transformed lymphoid cells. Twenty-five percent of the pp59v-rel was present in a minor complex that contained the majority of p75c-rel along with p115 and p124. In nuclear extracts of REV-T-transformed lymphoid cells, pp59v-rel was complexed with pp40. The two high-molecular-weight proteins (p115 and p124) and p75c-rel were not detected in the nuclear complex. In the cytosolic complexes, pp40 was heavily phosphorylated, whereas the nuclear form was much less extensively phosphorylated.
A revisit of the equilibrium assumption for predicting near-wall turbulence

Abstract In this study, we revisit the consequence of assuming equilibrium between the rates of production ( $P$ ) and dissipation $({\it\epsilon})$ of the turbulent kinetic energy $(k)$ in the highly anisotropic and inhomogeneous near-wall region. Analytical and dimensional arguments are made to determine the relevant scales inherent in the turbulent viscosity ( ${\it\nu}_{t}$ ) formulation of the standard $k{-}{\it\epsilon}$ model, which is one of the most widely used turbulence closure schemes. This turbulent viscosity formulation is developed by assuming equilibrium and use of the turbulent kinetic energy $(k)$ to infer the relevant velocity scale. We show that such turbulent viscosity formulations are not suitable for modelling near-wall turbulence. Furthermore, we use the turbulent viscosity $({\it\nu}_{t})$ formulation suggested by Durbin (Theor. Comput. Fluid Dyn., vol. 3, 1991, pp. 1–13) to highlight the appropriate scales that correctly capture the characteristic scales and behaviour of $P/{\it\epsilon}$ in the near-wall region. We also show that the anisotropic Reynolds stress ( $\overline{u^{\prime }v^{\prime }}$ ) is correlated with the wall-normal, isotropic Reynolds stress ( $\overline{v^{\prime 2}}$ ) as $-\overline{u^{\prime }v^{\prime }}=c_{{\it\mu}}^{\prime }(ST_{L})(\overline{v^{\prime 2}})$ , where $S$ is the mean shear rate, $T_{L}=k/{\it\epsilon}$ is the turbulence (decay) time scale and $c_{{\it\mu}}^{\prime }$ is a universal constant. ‘A priori’ tests are performed to assess the validity of the propositions using the direct numerical simulation (DNS) data of unstratified channel flow of Hoyas & Jiménez (Phys. Fluids, vol. 18, 2006, 011702). The comparisons with the data are excellent and confirm our findings.
Factors Influencing Implementation of Infrastructure Development Projects in the Renewable Energy Sector in Kenya: a Case of Kenya Power and Lighting Company Limited

xi CHAPTER ONE: INTRODUCTION . 1 1.1 Background to the Study . 1 1.2 Statement of the Problem . 3 1.3 Purpose of the Study . 4 1.4 Objectives of the Study . 4 1.5 Research Questions . 5 1.6 Significance of the Study . 5 1.7 Limitations of the Study. 6 1.8 Delimitations of the Study . 6 1.9 Assumptions of the Study . 7 1.10 Definition of Significant Terms used in the Study . 7 1.11 Organization of the Study . 7 CHAPTER TWO: LITERATURE REVIEW . 9 2.
Lifetime Earnings for Physicians Across Specialties

Background:Earlier studies estimated annual income differences across specialties, but lifetime income may be more relevant given physicians’ long-term commitments to specialties. Methods:Annual income and work hours data were collected from 6381 physicians in the nationally representative 2004–2005 Community Tracking Study. Data regarding years of residency were collected from AMA FREIDA. Present value models were constructed assuming 3% discount rates. Estimates were adjusted for demographic and market covariates. Sensitivity analyses included 4 alternative models involving work hours, retirement, exogenous variables, and 1% discount rate. Estimates were generated for 4 broad specialty categories (Primary Care, Surgery, Internal Medicine and Pediatric Subspecialties, and Other), and for 41 specific specialties. Results:The estimates of lifetime earnings for the broad categories of Surgery, Internal Medicine and Pediatric Subspecialties, and Other specialties were $1,587,722, $1,099,655, and $761,402 more than for Primary Care. For the 41 specific specialties, the top 3 (with family medicine as reference) were neurological surgery ($2,880,601), medical oncology ($2,772,665), and radiation oncology ($2,659,657). The estimates from models with varying rates of retirement and including only exogenous variables were similar to those in the preferred model. The 1% discount model generated estimates that were roughly 150% larger than the 3% model. Conclusions:There was considerable variation in the lifetime earnings across physician specialties. After accounting for varying residency years and discounting future earnings, primary care specialties earned roughly $1–3 million less than other specialties. Earnings’ differences across specialties may undermine health reform efforts to control costs and ensure adequate numbers of primary care physicians.
Combination Therapy Stroke Trial: Recombinant Tissue-Type Plasminogen Activator with/without Lubeluzole

Background: A neuroprotective drug may be safe and effective if given very early and in combination with recombinant tissue-type plasminogen activator (rt-PA) to acute stroke patients. No clinical trial has yet tested this hypothesis. Objective: To assess the feasibility, safety and efficacy of simultaneously combining the neuroprotective drug lubeluzole with rt-PA. Method: Patients who qualified for and received rt-PA within 3 h of symptom onset were randomly allocated 1:1 to lubeluzole (7.5 mg i.v. over 1 h, then continuous 5-day infusion of 10 mg/day) or placebo. Infusion of the study medication was started before the end of the 1-hour rt-PA infusion. Inclusion criteria were the same as those of the FDA-approved guidelines for rt-PA, plus National Institutes of Health Stroke Scale (NIHSS) >5 and absence of serious ventricular arrhythmia, atrioventricular block or Q–T >450 ms. EKG was continuously monitored until 48 h after treatment. The primary outcomes were adverse events, especially hemorrhage and severe arrhythmia, and functionality as determined by the Barthel Index divided into >70,0–70 and dead. Results: 89 patients were randomized at 34 centers over 8 months. The study was terminated by the sponsor before the planned enrollment of 200 patients when a concurrent phase 3 trial of lubeluzole versus placebo given up to 8 h after stroke was negative. In our study, the mean NIHSS was 14.5, and the mean time from symptom onset to rt-PA was 2.5 h and to randomization to lubeluzole or placebo 3.2 h. Mortality was 26%, intracerebral hemorrhage occurred in 10% and serious adverse events in 51%. There were no differences between the two treatment groups in any of these variables, outcomes or in the Barthel Index or other measures of functionality. Conclusion: Combining neuroprotective drugs such as lubeluzole simultaneously with rt-PA is feasible and safe. The efficacy of this strategy, using a potentially more effective neuroprotective agent, should be evaluated in an adequately powered clinical trial.
Green Innovation Regarding Electromobility in Germany and China: Who and How to Get Involved?

Copyright © The Author(s). 2018 This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. INTRODUCTION
IMPORTANCE-PERFORMANCE ANALYSIS: REVIEWING THE EVALUATION OF LICENSING SERVICE FOR PRODUCTION CERTIFICATE OF HOME FOOD INDUSTRY

The Importance-Performance Analysis (IPA) method is applied in market research to measure the applicant’s satisfaction level. This research aims to evaluate and highlight the use of IPA as a management tool in measuring the quality of licensing service for production certificate of home food industry (PIRT). We suggest that this method can be easily implemented in licensing services for home production certificate as work results that include service user input. The research was conducted at the health office through a valid questionnaire: SERVQUAL. This instrument explores the level of service quality perceived by users of licensing service. It was carried out in one area of health resource development; the Ponorogo Health Office in 2016 on food processing licenses which included processed dried fish, dried poultry, coconut, flour, oil and fat, jam or jelly and the similar things, sugar or confectionery and honey, soft drinks or powders, spices, and processed fruit. This research was divided into two stages: first, the beneficiaries answered the questionnaire before using the licensing service and second, the same beneficiaries answered the questionnaire after completing licensing service for food production certificate. Based on the data from the graphs produced by SERVQUAL, it was found that tangible dimension has the highest average in both expectations and perceptions. The responsiveness dimension showed the most negative value among the other dimensions. IPA may be effective for use in licensing home food products because it highlights the key points that must be improved in licensing service for production certificate of home food industry.
Evaluating Cost Effective Control Strategies for dealing with Beaver Infestation in Tierra del Fuego

In 1947, the non-native species of North American beaver was introduced in the southern tip of South America, with the goal to encourage fur industry. Since then, beaver population has spread and grown many fold, resulting in a huge challenge to control its population in Tierra del Fuego, covering regions in both Chile and Argentina. Primary reasons for their rapid spread in part include good ecological conditions and lack of natural predators, thus causing huge ecological damage in the region. This study uses data from Tierra del Fuego on growth rates, dispersal rate of beaver population and types of available controls to develop dynamic models of population spread. These models are used to design effective population control policies that include trapping and hunting. Monetary cost for the implementation of these controls are considered in order to optimize costs and reduction policies for development of long lasting strategies.
Reliability-Oriented Assessment of a DC/DC Converter for Photovoltaic Applications

There is a trend toward increasing the performance of power electronics converters used in photovoltaic systems. However, parameters such as reliability, efficiency, and complexity might be in conflict. In this paper, the design of a simple DC/DC interleaved boost converter is assessed. It takes advantage of state-of-the-art power devices that have fast switching times. It is shown that requirements of low complexity, high reliability, and high efficiency can be satisfied, without resorting to switching aids, provided that the devices are selected with reliability in mind. A 1 kW prototype attained a peak efficiency as high as 98%, and a predicted mean time between failures of 100,000 hours at 80 C.
Immunolocalization of acidic and basic fibroblast growth factors during mouse odontogenesis.

Acidic and basic fibroblast growth factors (aFGF and bFGF), are both known to bind to extracellular matrix components, particularly proteoheparin sulfates, and to regulate in vitro proliferation, differentiation and morphology of cells of neuroectodermal and mesodermal origins. Their patterns of distribution were studied during mouse odontogenesis by means of indirect immunofluorescence and immunoperoxidase histochemistry on frozen fixed sections and after Bouin's fixative and paraffin embedding. Localization of aFGF on frozen fixed sections was observed in the oral epithelium, dental lamina and oral mesenchyme (day-12 of gestation), the stellate reticulum and oral epithelium (day-14), the stratum intermedium and at the basal and apical poles of preameloblasts at bell stage. After birth aFGF epitopes were localized within the predentin-dentin area, the stratum intermedium and at the secretory pole of ameloblasts. There was no staining with anti-aFGF antibodies after Bouin's fixative and paraffin embedding. In contrast, using this protocol, intense stainings were found with anti-bFGF antibodies predominantly within dental and peridental basement membranes and mesenchyme: staining of the dental basement membranes was transient (bud and cap stage) and discontinuous; a preferential concentration of bFGF epitopes in the condensed dental mesenchyme of incisors (cap stage) and the dental papillae mesenchymal cells of molars (bell stage) was observed in the posterior and the cervical part of tooth germs. An intense immunostaining of the stellate reticulum with anti-bFGF antibodies was also found on paraffin sections from bud to bell stage. (ABSTRACT TRUNCATED AT 250 WORDS)
Putting Metaphysics First: Essays on Metaphysics and Epistemology

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Digital Cement: Software Portfolio Architecture, Complexity, and Flexibility

This paper is about the relationship between an organization’s software portfolio architecture and its ability to make changes to it. Responding to business and technology changes often involves modifying the software portfolio and the speed and cost of making changes to the software portfolio is a measure of the system’s flexibility. The specific research question is: “How does software portfolio architecture affect software portfolio flexibility? ” This research develops measures of architectural and component complexity and hypothesizes that these constructs affect one dimension of software portfolio flexibility: architectural flexibility. The hypotheses are tested by (1) collecting component and dependency data from a biopharmaceutical company’s software portfolio, (2) combining this data with survey, system instrumentation, and archive data, and then (3) estimating and interpreting multiple regression models. The general conclusions from the research are that both complexity at the component level and complexity at the architectural level affect software portfolio flexibility.
A Program Evaluation of an Academic Integrative Healthcare Center: Barriers to, and facilitators in, applying Integrative Medicine to Primary Care

Author(s): Khorsan, Raheleh | Advisor(s): Stokols, Daniel; Coulter, Ian D | Abstract: A number of earlier studies have evaluated various aspects of Integrative Health Care (IHC). However, little is known about specific parameters of IHC integration in academic institutions. This dissertation presents the findings from a two-year program evaluation conducted at a university-based academic medical center and clinic for IHC. A major objective of the research was to identify perceived barriers and facilitators of IHC and address potential models of successful integration. The study employed a mixed-methods approach incorporating qualitative observations and interviews conducted with key-stakeholders, patients and health care providers. In addition, quantitative analyses incorporating demographic data and participants’ responses to a patient satisfaction scale were conducted. The majority of the themes from the literature and interviews include structural factors, especially external barriers for IHC (i.e., costs, insurance payment and regulations) and internal barriers (i.e., lack of profits, clinic or appointment waiting time). Whereas shared values, culture, and communication to foster trust, empathy and knowledge exchange are essential for actualizing IHC integration. In addition, collaborative, and team-based approaches that influence the design of the integration and can influence the evolutionary path of IHC. Although signs of integration were apparent, significant challenges still remained that prevented IHC providers from operating as academic hospital providers. An integrated interdisciplinary change strategy is needed that engages the IHC providers in mainstream transdisciplinary healthcare, education and research opportunities. Successful IHC integration will need to continue to addresses wider structural and political barriers.