Miracle-dz/UniFAR-FTUs huggingface dataset:
Expérimentation et modélisation du comportement hyperélastique d'une membrane dans une cartouche microfluidique

La necessite de manipuler des volumes discrets de liquide en microfluidique dans le domaine de la sante, conduit les chercheurs a trouver des technologies innovantes. Une possibilite est de travailler avec des chambres fluidiques limitees par une membrane hyperelastique, activee pneumatiquement. Dans cet article, une methode microfluidique pour caracteriser la deformation d'une telle membrane est presentee. Les resultats issus de deux modeles hyperelastiques, les modeles Yeoh et Mooney-Rivlin, sont confrontes a des resultats experimentaux qui ont ete obtenus. Cette comparaison repose sur les differentes valeurs des parametres utilises dans ces modeles que la litterature scientifique propose.
EVALUATION IMPLEMENTATION STRATEGIC PLANNING OF HEIS IN THE BALANCED SCORECARDS CUSTOMER PERSPECTIVE, SETTING IN UNIVERSITAS INDONESIA

Tumbur Tobing 1 , Rugaiyah 2 and Ivan Hanafi 2 . 1. Student of Postgraduate in Education Management Universitas Negeri Jakarta Indonesia. 2. Professor of Postgraduate in Education Management Universitas Negeri Jakarta Indonesia. Manuscript Info Abstract . Manuscript History Received: 03 October 2019 Final Accepted: 05 November 2019 Published: December 2019
Efectos de la cirugía de estimulación cerebral profunda, sobre el aprendizaje motor en la Enfermedad de Parkinson

La Enfermedad de Parkinson (EP), es una condicion neurodegenerativa que se caracteriza principalmente por una diversa gama alteraciones motoras. Una de sus alternativas terapeuticas es la Estimulacion Cerebral Profunda (DBS por sus siglas en ingles), que ha mostrado ser un tratamiento eficaz de la sintomatologia en la EP, sin embargo, no se ha esclarecido, si la disminucion en las alteraciones de movimiento solo estan relacionadas con mejorar la capacidad de controlar el movimiento o tambien facilita el aprendizaje motor. Objetivo: Describir los cambios del aprendizaje motor durante la realizacion de tres tareas motoras, en pacientes con EP con DBS, versus pacientes con EP que no han sido intervenidos quirurgicamente y un grupo control de personal potencialmente sanas. Metodologia: Se realiza una muestra a conveniencia con 7 personas con EP y DBS (Grupo 1), 7 con EP sin DBS pero con fluctuaciones motoras (Grupo 2) y 7 personas potencialmente sanas (Grupo 3), los cuales participaron en un programa de aprendizaje motor de 2 semanas durante 8 dias, usando los Test de Dedo-Nariz, Whipple y Equilibrio. Resultados: El Grupo 1 muestra un patron de aprendizaje distinto a los Grupos 2 y 3, con menor mejoria en el desempeno de las tres pruebas, pero solo con diferencias estadisticamente significativas en las pruebas Whipple y de Equilibrio, no obstante este ultimo test no presenta datos concluyentes. Conclusiones: En la poblacion estudiada se observa que la DBS modifica la forma en que las personas con EP aprenden diferentes tareas motoras.
Młodzież „Pokolenia Z” wobec wdzięczności w kontekście wychowania w rodzinie

Przemiany zachodzące we współczesnym społeczeństwie i rodzinie powodują, że zmienia się znaczenie tradycyjnych środowisk wychowawczych. Kształtowanie się postaw młodych ludzi dokonuje się w coraz większym stopniu przy udziale mass mediów i grup rówieśniczych, ale rodzina wciąż stanowi potencjał dla rozwoju osobowościowego jej członków. Jest to widoczne w kształtowaniu się postaw młodzieży wobec wdzięczności, posiadającej ważne znaczenie dla funkcjonowania jednostki i społeczeństwa. Badania wypowiedzi 200 przedstawicieli Pokolenia Z pokazały, że wychowanie w rodzinie wyraźnie sprzyja okazywaniu oraz rozwojowi wdzięczności, a najskuteczniejszy w tym względzie jest osobisty przykład rodziców. Współpraca środowisk wychowawczych w celu wzmacniania poczucia i okazywania wdzięczności przez młodzież jest istotnym postulatem wynikającym z przeprowadzonych badań empirycznych.
Join the fight against poverty: utilizing HRD practices to support pathways to sustainable employment and decent work

HRD as a field has long been motivated by a humanistic view and concerns itself with national development, societal development, and critical issues in addition to performance improvement in organizations. For example, in 2006, an issue of Advances in Developing Human Resources (ADHR) explored national HRD policies and strategies on poverty alleviation in Brazil, Morocco, and the Philippines. In 2012, another ADHR issue addressed societal and community development linked to poverty alleviation. The same year, Storberg-Walker (2012), the editor of Human Resource Development Review (HRDR) at the time, called for a paradigm shift in the field of HRD for workforce development and public good. More recently, another past editor of the HRDR, Torraco (2018) argued for more HRD research to help break the self-perpetuating cycle that has trapped people of low-income and low education. The journal of Human Resource Development International is versed to this topic as well. A quick search using the keyword poverty yielded more than 60 publications in this journal. Scholars in HRD have acknowledged and encouraged studies that explore beyond organizational boundaries to look at different employment tiers and community development agencies designed to meet the specific needs of diverse groups of learners that include lowskilled and low-literacy populations. A recent interaction with a local community-based organization led me to investigate the potential of HRD practices to elevate individuals from poverty through increased employability and career adaptive behaviours. This organization started as an emergency relief food pantry in 2004 and has been making a steady effort to consistently renew itself. In 2014, the organization re-evaluated the meaning of helping people and determined that the purpose was not only to relieve them from short-term emergency needs but also assist them in moving towards dignified living. The organization redesigned its programming to offer a relationship-based programme aimed at increasing participants’ social connection with the community, reduce isolation, and increase self-esteem through a dignified experience of being part of an organization. The relationship-based programme offers people the opportunity to sign-up for ‘volunteer’ work that will earn credit to shop at the store operated by the organization. While ‘volunteering’ at the store, the individuals socialize with other staff members, being part of a team. They also have opportunities to participate in financial education, computer literacy, GED training, personal development, job preparedness, adult education classes, and have access to a computer lab. Recently, the organization initiated an evaluation process using structured interviews to track its progress and seek improvement ideas. The findings revealed very positive perceptions of the social relationship built through the ‘volunteer’ work. The participants HUMAN RESOURCE DEVELOPMENT INTERNATIONAL 2020, VOL. 23, NO. 1, 1–4 https://doi.org/10.1080/13678868.2020. 1701222
Determination of nuclear DNA content and ploidy of some Bromus L. germplasm by flow cytometery

The objective of this study was to determine nuclear DNA content and ploidy of 48 Bromus L. gene bank accessions obtained from USDA by flow cytometry. Based on the results of the flow cytometric analysis, the mean 2C nuclear DNA content of Bromus accessions used in the study varied between 11.43 pg with 26.62 pg. The nuclear DNA content differences among Bromus L. accessions were statistically significant at P<0.01 level. The accessions were easily separated into three distinct groups according to their DNA contents. The mean 2C nuclear DNA content of the groups were 11.82, 22.43 and 26.17 pg (min. and max. values of group were between 11.43–12.65 pg, 21.45–22.77 pg, 25.48–26.62 pg, respectively). Nuclear DNA content of the accessions were correlated with their ploidy levels by counting chromosomes of the one plant from each group with classical staining methods. In conclusion, majority of the Bromus accessions (33 out of 48) analysed in the study were tetraploid with 2n=4x=28 chromosomes. Ten and five of the remaining accessions were octaploid (2n=8x=56) and (2n=10x=70) decaploids, respectively. No decaploid B. inermis plant reported until today. However, decaploids were reported for B. riparius and B. biebersteini species. Therefore, decaploid plants determined in this study should be considered as either B. riparius or B. biebersteini.
A Study Analysis on Effect of Software Scope Management and Scope creeping Factors in Software Project Management

Scope, time, and cost permanently effects each other and most of Information Technology projects fails due to these three factors. Scope shifting mostly occur due to time and cost. At project start, lack of understanding of project and product scope is focal involvement that leads to unsuccessful projects. Complete software scope definition determines quality of project. Defining the customer requirement and the definite scope of project has key role for implementation of project management. The complications originates when systems are developed from impractical expectations and misunderstanding requirements. These problems are cause of many changes, occurs in system development and leads to poor scope management. Scope creep is one of the momentous prompting parameter on the success of project. The failure in manage scope creep leads for 80 percent of software projects failure. However, using agile approach the impact of scope creep on projects become insignificant. A correctly distinct scope tends us to develop a quality product, within identified plans and decided cost to the stake-holders.
The impacts of FOREX fluctuations on international construction projects

The international construction project is a highly valuable market project and many of the contractors would like to be participate. This is because they are misled with the exchange rate (money) and instantly attracted with the profit they assumed will be gained after the project is completed. In fact, without noticing that they will be affected with the FOREX’s fluctuations which might complicate the project further. In addition, many new vendors nowadays will try their luck in construction business without making a good judgement on the risks. So, the objective of this study is to identify the impacts of FOREX fluctuations on those perspectives at international level. This study also uses quantitative method through questionnaire survey that were distributed randomly, and the result obtained were from top management and non-top management in construction hierarchy with different level of experiences. The collected data were analysed by using two methods which are Statistical Package for Social Science (SPSS) and Microsoft Excel. The SPSS software is used to process the regression analysis for the impacts of FOREX data of the questionnaire. The Relative Importance Index then is applied to run the data for capability and mitigation actions in determining the ranking of priorities. Overall, the impacts of FOREX fluctuation on international construction projects have been identified with regards to three mechanisms which are business management, technical and financial. These outputs are useful as a guideline for international construction project companies when they are venturing into this challenging market especially in terms of managing/expediting quality, completion period, and optimising cost of the projects.
Eficacia de la terapia manual articulatoria vertebral en pacientes con migraña

La migraña es uno de los trastornos del sistema nervioso más comunes y se considera la tercera causa de incapacidad en el mundo en menores de 50 años. El tratamiento de la migraña mediante terapia manual articulatoria vertebral (TMAV) puede ser efectivo, sin embargo, existe más controversia que en otros tipos de cefaleas. El objetivo del presente estudio es valorar los cambios producidos tras la aplicación de TMAV en pacientes con migraña en cuanto a la intensidad del dolor y su impacto.44 participantes con una edad media de 39 años (desviación típica= 9.47) con migraña, fueron divididos en dos grupos de forma aleatoria: 1) grupo TMAV (n=22), 2) grupo control (n=22). Se realizaron dos evaluaciones, pretratamiento y postratamiento, y se emplearon la Escala Visual Analógica (EVA) y el Cuestionario de Impacto de las Cefaleas (HIT-6). No hubo diferencias significativas entre los dos factores (es decir, medidas tiempo y grupos) ni en EVA ni en HIT-6 (p> 0.05), sin embargo, hubo diferencias significativas en el grupo TMAV entre el pretratamiento y el postratamiento en EVA (p= 0.004) y en HIT-6 (p= 0.014). La TMAV en pacientes con migraña, disminuye la intensidad del dolor y el impacto asociado a la migraña, y podría ser un tratamiento adecuado en combinación con la medicación.
Research on Estate Mortgage Risk Control Based on RF-XGboost Model

With the expansion of the real estate mortgage market, commercial banks urgently need efficient and convenient means to deal with the high bad debt rate of real estate mortgage loans. Meanwhile, government departments also have desire to establish a scientific and effective system to supervise the real estate mortgage market. Therefore, the concept of machine batch evaluation in this paper establishes an intelligent real estate evaluation model based on RF-XGboost model, which can not only complete the market value evaluation subject of the designed real estate by means of machine batch evaluation with high efficiency and low cost, but also help to promote the standardization process of the evaluation industry, make the mortgage market transparent, and finally realize the effective control of real estate mortgage risks.
A comparative evaluation of whole blood total antioxidant capacity using nitroblue tetrazolium reduction test in patients with oral lichen planus and healthy subjects

Background and Objectives: Oral Lichen Planus is an inflammatory disease of unknown etiology. Recently, reactive oxygen species have been implicated in the pathogenesis of this disease. The investigation of disease associated oxidant-antioxidant imbalance is hard because constrained availability of specific biomarkers of oxidative stress, and the fact that measurement of individual antioxidant may give a deceptive image due to the fact that antioxidants work in concert through chain breaking reactions. Therefore, analysis of total antioxidant capacity may be the maximum applicable investigation. As blood is continuously exposed to oxidative stress, the aim of this study was to analyze overall blood antioxidant potential in healthy and oral lichen planus patients through the use of Nitroblue Tetrazolium reduction test. Methods: The study included 30 individuals which were selected from outpatients department with age ranging between 30 and 60 years, 15 patients in oral lichen planus group and 15 in healthy group (control), respectively. Blood samples were collected early morning and tested using Nitroblue Tetrazolium Reduction test (NBT). The test was performed and gave us the clear picture of whole blood total antioxidant capacity. Results: Results were obtained, analyzed and results showed that the total antioxidant capacity in whole blood of patients with oral lichen planus was significantly decreased as compared with healthy group (P
Effect of Excess Fertilizers and Nutrients: A Review on Impact on Plants and Human Population

Unduly high concentration or intake of elements and nutrients can have adverse effect on plant growth. Also few elements, especially heavy metals have tendency to bio-accumulate. The plants can become source of excess heavy metal intake in human beings. Meeting the growing need for food is a challenge. For this, agricultural land per unit area is required to achieve maximum efficiency. Use of fertilizers and nutrients is one way to supply achieve this. The presence of heavy metals affects the plant growth. Excess use of fertilizers may lead to heavy metal accumulation, eutrophication and accumulation of phosphate and nitrate. Excessive phosphorus is potential threat to water quality. Policies and rules for encouraging effective and environment friendly use of fertilizers and its supply can improve the soil quality and prevent the adverse effects on human beings.
Evaluation of the Setting of the Global Promotion of the Czech Republic Destination

Internationalisation is an increasingly common strategy for all types of companies across sectors, especially for tourism and destination management. The paper aims to evaluate the effectiveness of the current setting of marketing promotion of selected economies in the global market. The cost benefit analysis method compares the costs of individual international campaigns with the benefits measured by the number of arriving tourists from each target market. The costs and benefits of the internationalisation of the Czech Republic’s marketing strategy (based on the CzechTourism data evidence) are subsequently quantified per unit, or how much money was needed to attract one tourist (given the cultural distance between economies) and the total amount of consumer spending of the tourist with the relevant source economy. The analyses showed paradoxically the low efficiency of the international campaign in Austria and Slovakia which, due to the amount of money spent, could not attract enough tourists. The net benefits of these promotions are EUR 74.84 for Austria and EUR 96.52 for Slovakia. On the other hand, the most effective was the campaign in Russia, which brought EUR 301.08 net profit. Marketing campaigns in India and the USA, where net profit exceeded EUR 200, can be considered successful.
Strategic flexibilities: valuation of a company with the application of the Real Options Theory

Goal: In this paper, a binomial model is proposed to evaluate the option of deferring an investment and expanding the operational scale of a forest-based company that will perform the de-duplication of Pinus sp. and will market packaging for storage and transportation of vegetables. Design/Methodology/Approach: The proposed model measured the options of deferring an investment and expanding the operational scale of the forest-based company. In this perspective, the model of evaluation used was the binomial model in discrete time using the Real Options. Results: It was observed that the inclusion of management flexibilities in the decision making process has added value to the investment project; therefore, the project of investments in real assets proved to be economically feasible. Limitations of the investigation: The studies that address the corporate finance framework based on real data are a restrictive factor, due to the lack of collaboration of companies, that is, the availability of information that is usually classified. Practical implications: The study was based on the real data of a company; therefore, it can be adopted as a stimulus to the Real Options approach to the decision making of entrepreneurs or researchers. Originality/value: The focus of the study was to contemplate the managerial flexibilities of an industry of the secondary sector of the Brazilian economy, which performs the unfolding of wood, demonstrating the innovation of the technique approach used in this market segment.
Use of complementary therapies for side effect management in breast cancer: evidence and rationale

Women diagnosed with breast cancer can experience chronic side effects after curative treatment concludes, negatively impacting survivorship. The most prevalent side effects addressed in the medical and nursing literature include symptoms such as hot flashes, fatigue, myalgias/arthralgias and cognitive impairment. Complementary therapies, particularly natural products including herbs, dietary supplements, vitamins, minerals, and probiotics, and mind–body techniques that include such modalities as yoga, meditation, massage, acupuncture, relaxation, tai chi and hypnosis show promise for treatment of some of these symptoms associated with cancer care. However, the research in this area is nascent and much more work is needed to understand symptom physiology and mechanisms of action of complementary therapies. The purpose of this paper was to summarize key evidence from Phase II and III randomized clinical trials in order to provide guidance to distinguish promising versus nonpromising interventions for sympt.
Recherche de nouveaux biomarqueurs sériques de dépistage précoce du cancer de l'ovaire en spectrométrie de masse

Bien que peu frequent avec une prevalence de 40 cas pour 100 000 femmes, le cancer de l'ovaire est responsable d'une importante mortalite, au point d'etre la premiere cause de deces par cancer gynecologique en France. Cela s'explique essentiellement par l'absence de moyens de depistage precoce, tels qu'il en existe pour d'autres cancers (notamment sein ou colon), alors que le pronostic est conditionne par la precocite du diagnostic (90% de survie a 5 ans en cas de diagnostic au stade I contre seulement 10 a 15 % au stade IV). En effet, les signes cliniques sont tardifs et tres peu specifiques, et l'echographie est peu performante en raison du faible volume ovarien a un stade precoce chez les femmes menopausees, population le plus explosee a ce type de cancer. Le biomarqueur actuellement utilise, le CA125 presente une sensibilite et une specificite trop faibles pour son utilisation en depistage de masse, alors que sa valeur predictive le rend tres interessant en evaluation de la reponse au traitement ou dans le depistage de recidives. L'enjeu dans le depistage du cancer de l'ovaire a un stade precoce repose donc sur la decouverte de nouveaux biomarqueurs, facilement accessibles par test serique.
Immunotherapies in phase II and III trials for the treatment of systemic lupus erythematosus

ABSTRACT Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by highly heterogeneous clinical manifestations and a multi systemic involvement. SLE is prone to relapses and remissions, which makes the management challenging. Moreover, conventional therapies may have considerable side-effects, which highlights the demand for new therapeutic strategies. The progress towards a better understanding of the underlying pathogenesis has led to the development of biological therapies targeted directly against crucial molecular mediators of SLE. Areas covered: In this review we analyzed available biological therapies, phase II and III trials and upcoming new therapies that are currently under development for SLE treatment. Expert opinion: The complex pathogenesis of SLE is far from being fully understood. Evidence towards a better understanding of the pathogenic pathways, the cellular and molecular mediators involved in SLE are emerging. Henceforth, new biological therapeutic options targeting crucial molecular mediators involved in the pathogenesis of SLE are being developed. In the future, the management of SLE could profit from the use of biological therapies that are tailored towards the individual patient’s specific clinical manifestations, taking into account their genetic background and pathogenic fingerprint.
Managing Diabetes in Children and Adolescents—Is There an Optimal Regimen?

Treatment of Type 1 Diabetes in Children and Adolescents Diabetes is one of the most common chronic conditions affecting children worldwide. Statistics gathered by the National Institutes of Health (NIH) in 2005 revealed that one out of every 400–600 children in the US had been diagnosed with type 1 diabetes. This figure increases annually, with reports of the global incidence of diabetes in children and adolescents increasing at a rate of 3% per year. The greatest increase in incidence has been reported in children ≤5 years of age. This equates to approximately 190,000 children, with their families attending to the usual demands of ensuring the physical, intellectual, and emotional health of a toddler, school-age child, or adolescent while trying to maintain their blood-glucose levels in a range as close to normal as possible.