Miracle-dz/UniFAR-FTUs huggingface dataset:
Learning Experiences with Active Learning Method Applied during the Early Years of Undergraduate Nursing Students :Through Global Nursing Training Course in the Philippines

Purpose: The purpose of this study is to describe the experiences of the first year undergraduate nursing students in a Japanese private university. It illustrates their progress in learning through participating in sequential steps in preparatory studies with active learning methodology in the Global Nursing Training Course held in the Philippines in March 2014. Methods: All of the study participants (N=28) were 1 year undergraduate nursing students including four male and 24 female students between the ages of 19 and 35 who participated in the global nursing training course in the Philippines. They have voluntarily applied for the program and all of them were selected. Result : Analysis of active learning reflective journals demonstrated the learners’ progress in three phases, preparatory, in the field, and post-training course. Study results illustrated that use of active learning strategies led to gain in knowledge, critical thinking, behavioral modification, and motivation, and willingness to challenge avoidant behavior of the learners. The sequential steps of preparatory study helped the learners to overcome difficult tasks and to set goals that reflect their future desires. Conclusion: Data from participants’ reflective journal demonstrated changes in study attitudes, sense of self, and the significance of having real involvement as global nurses. Although implementation of active learning strategies requires planning and effort by both students and teachers or mentors, this study has documented benefit from starting in the early stages of the undergraduate program to maximize benefits such as critical thinking and self-reflection as students continue their nursing education.
Assessment of effectiveness of different teaching methodologies and perception about pharmacology among 2nd year dental students: A cross-sectional study

CONTEXT: Reviewing the teaching programs by taking feedback from the students at regular intervals gives us input into the strength of the pharmacology curriculum so that necessary reforms can be undertaken to improve students' performance. AIMS: This study aims to obtain feedback from 2nd year Bachelor of Dental Surgery (BDS) students regarding their preferred teaching method and their perception about pharmacology. SETTING: A study done at Mallareddy Dental College for Women (MRMCW), Hyderabad. DESIGN: A cross-sectional survey. SUBJECTS AND METHODS: A prevalidated questionnaire containing 17 questions with 2–6 options each were administered to 73 2nd year BDS students studying at MRMCW, Hyderabad. The data so obtained were entered into Microsoft Excel and statistical analysis was done. STATISTICAL ANALYSIS USED: Descriptive statistics were used for analysis of the data. RESULTS: The majority (84%) of students preferred lecture as their preferred teaching method in Pharmacology. Most students wanted lecturers to use liquid crystal display (LCD) projection while taking class (37.8%). 70.8% of students did not prefer studying in tutorials while 29% of them wanted tutorials. The majority of students (57.1%) wanted revision classes regularly after completion of each system, and 84.7% of students wanted pharmacology practicals to be a combination of pharmacy practicals with clinically oriented classes and 93% of them wanted pharmacology to be integrated with medicine. CONCLUSIONS: Lectures using LCD projection was the preferred mode of learning in this setting. There is a need to incorporate more clinically oriented exercises in pharmacology practicals to prepare the students toward being a competent dentist.
Elegant antidisturbance fault‐tolerant control for stochastic systems with multiple heterogeneous disturbances

In this article, the elegant antidisturbance fault‐tolerant control (EADFTC) problem is studied for a class of stochastic systems in the simultaneous presence of multiple heterogeneous disturbances and time‐varying faults. The multiple heterogeneous disturbances include white noise, norm bounded uncertain disturbances and uncertain modeled disturbances with multiple nonlinearities and unknown amplitudes, frequencies, and phases. The time‐varying fault signals are caused by lose efficacy of actuator. To online estimate uncertain modeled disturbances and time‐varying faults, a novel composite observer structure consisting of the adaptive nonlinear disturbance observer and the fault diagnosis observer is constructed. The novel EADFTC strategy is proposed by integrating composite observer structure with adaptive disturbance observer‐based control theory and H∞ technology. It is proved that all the signals of closed‐loop system are asymptotically bounded in mean square under the circumstances of multiple heterogeneous disturbances and time‐varying faults occur simultaneously. Finally, the effectiveness and availability of proposed strategy are demonstrated by means of the numerical simulation and a doubly fed induction generators system simulation, respectively.
Prevalence ofEscherichia coli Strains withLocalized, Diffuse, and Aggregative Adherence toHeLaCells inInfants with Diarrhea andMatched Controls

Todetermine thepossible role ofEscherichia coli strains withthree different patterns ofadherence toHeLa cells incausing diarrhea ininfants inSaoPaulo, Brazil, we studied stool specimens from100infants up to1 yearofagewithacutediarrheal illnesses and100age-matched control infants without recent diarrhea. E.coli withlocalized adherence toHeLacells was muchmore common inpatients (23%)thanincontrols (2%)(P< 0.0001) andwas detected more frequently thanrotavirus (19%)was inpatients, eventhough thestudy was conducted during thecoldest monthsoftheyear.Most(80%)oftheE.coli colonies withlocalized adherence were oftraditional enteropathogenic E.coli serotypes. Little difference was foundbetween patients and controls intherateofisolation ofE.coli withdiffuse adherence (31and32%,respectively) or aggregative adherence (10and8%,respectively). Agenetic probe usedtodetect aplasmid-mediated adhesin whichconfers expression oflocalized adherence proved tobe100%sensitive and99.9%specific indetecting E.coli with localized adherence toHeLacells. Although E.coli strains withlocalized adherence havenow beenshownto beenteric pathogens inseveral parts oftheworld, therole ofstrains showing diffuse adherence andaggregative adherence isstill uncertain. Bacterial adherence totheintestinal mucosaisessential to theability ofmany enteropathogenic Escherichia coli (EPEC)strains tocausediarrhea (2). Adhesion ofenterotoxigenic E.coli(ETEC)andenterohemorrhagic
Correlation of lower limb muscles strength and flexibility with pain and function in females with Patellofemoral Pain

step-down determine the analyzed using an independent t -test, Pearson correlation and There were significantly lower strength of the knee extensors, the knee flexors, the hip abductors and lateral rotators in the PFP group as compared to the healthy group (P <0.001). The hip medial rotators, illiotibial band and quadriceps flexibility in the PFP group were significantly lower compared with the healthy group (P <0.05). Based on regression analysis, quadriceps flexibility and hip abductor muscle strength may predict Kujalla (R 2 =0.20) and step-down scores (R 2 =0.16) in females with PFP. No significant correlation was found between pain intensity, function and muscle strength. Conclusion : lower limb muscles strength in females with PFP is significantly less than a healthy matched group. Qquadriceps muscle flexibility and the hip abductor muscles strength may predict Kujalla and step-down scores in females with PFP, respectively.
Étude de l'efficacité du parasitoïde Ganaspis cf. brasiliensis pour la gestion de Drosophila suzukii, ravageur invasif en culture de fraise sous abri

Drosophila suzukii est une espece invasive hautement polyphage originaire d’Asie qui s’attaque particulierement aux petits fruits rouges. Sa capacite a pondre dans les fruits sains cause d’importants degâts en culture de cerises et de fraises, notamment. A ce jour, il n’y a pas de methode de lutte satisfaisante contre ce ravageur tant au niveau sanitaire qu’environnemental, c’est pourquoi la lutte biologique est un levier d’action fortement etudie. Les parasitoides indigenes ne presentant pas une solution adequate, l’interet s’est donc porte vers les parasitoides exotiques. Dans le cadre du projet CASDAR DS², le parasitoide larvaire Ganaspis cf. brasiliensis a ainsi ete retenu comme candidat potentiel pour la lutte par acclimatation en raison de sa specificite pour D. suzukii et de son efficacite dans son aire d’origine. Deux souches de G. cf. brasiliensis, issues d’evaluations preliminaires en laboratoire, ont ete testees dans cet essai, en serre confinee, en culture de fraise hors-sol. Des lâchers de G. cf. brasiliensis ont ete realises dans 3 compartiments de serre etanches de 60m², sur une culture de fraise prealablement infestee par D.suzukii et compares a un temoin non traite. Cependant, aucun parasitoide n’a emerge des fruits preleves chaque semaine. Cet essai n’a donc pas permis de conclure sur l’interet du parasitoide comme agent de lutte biologique. Des etudes supplementaires seront menees dans les prochaines annees afin de determiner la reelle efficacite du parasitoide.
Entrepreneurship development in Japan: An empirical analysis

Objective: The purpose of this article is to evaluate the entrepreneurship development of Japan and comparing its performance against leading countries in the same region, mainly Hong Kong, and Taiwan. Research Design & Methods: We implement the Global Entrepreneurship Index GEI methodology, where the GEI methodology focuses on quality-related institutional and individual aspects of entrepreneurship. Moreover, we utilised a novel feature of the GEI the Penalty for Bottleneck PFB methodology to produce induction of which entrepreneurial elements should be addressed and how much effort needs it to lighten Japan bottleneck. Findings: Japan’s entrepreneurial performance is relatively modest compared to some countries in the same region, especially in individual variables. Japan’s entrepreneurial profile strengths are in the institutional features (e.g., country risk), while the instability in the profile back to individual variables (e.g., population perception and motivation). The country has three fundamental bottlenecks in its performance opportunity perception, start-up skills, and networking pillars. The GEI data used in the study only covers the 2006-2016 period. Japan should be focused on the three bottlenecks opportunity perception, start-up skills, and networking to improve its entrepreneurial performance by developing an education policy that focuses on entrepreneurship. Contribution & Value Added: This paper identifies the vulnerable aspects of Japan’s performance by using a novel methodology that combines individual and institutional variables in a single model. Also, the use of (PFB) to detect which entrepreneurial components should be addressed.
Giant African snail genomes provide insights into molluscan whole-genome duplication and aquatic-terrestrial transition

Whole-genome duplication (WGD) has been observed across a wide variety of eukaryotic groups, contributing to evolutionary diversity and environmental adaptability. Mollusks are the second largest group of animals, and are among the organisms that have successfully adapted to the nonmarine realm through aquatic-terrestrial (A-T) transition, and no comprehensive research on WGD has been reported in this group. To explore WGD and the A-T transition in Mollusca, we assembled a chromosome-level reference genome for the giant African snail Achatina immaculata, a global invasive species, and compared the genomes of two giant African snails (A. immaculata and Achatina fulica) to the other available mollusk genomes. The chromosome-level macrosynteny, colinearity blocks, Ks peak and Hox gene clusters collectively suggested the occurrence of a WGD event shared by A. immaculata and A. fulica. The estimated timing of this WGD event (∼70 MYA) was close to the speciation age of the Sigmurethra-Orthurethra (within Stylommatophora) lineage and the Cretaceous-Tertiary (K-T) mass extinction, indicating that the WGD reported herein may have been a common event shared by all Sigmurethra-Orthurethra species and could have conferred ecological adaptability and genomic plasticity allowing the survival of the K-T extinction. Based on macrosynteny, we deduced an ancestral karyotype containing 8 conserved clusters for the Gastropoda-Bivalvia lineage. To reveal the mechanism of WGD in shaping adaptability to terrestrial ecosystems, we investigated gene families related to the respiration, aestivation and immune defense of giant African snails. Several mucus-related gene families expanded early in the Stylommatophora lineage, functioning in water retention, immune defense and wound healing. The hemocyanins, PCK and FBP families were doubled and retained after WGD, enhancing the capacity for gas exchange and glucose homeostasis in aestivation. After the WGD, zinc metalloproteinase genes were highly tandemly duplicated to protect tissue against ROS damage. This evidence collectively suggests that although the WGD may not have been the direct driver of the A-T transition, it provided an important legacy for the terrestrial adaptation of the giant African snail.
Development of Lifting System for High-Elevation Inspection Robot Targeting Hanger Ropes

In this paper, we show the development of a lifting system and frame body for an inspection robot targeting hanger ropes of a suspension bridge. Infrastructure now requires regular inspection and such robots are expected to be used in places where manual inspection is difficult. The problems associated with the lifting system for the hanger-rope inspection robot studied in this paper include a long lifting distance (up to 100 m), postural stability against the influence of wind, and risk of falling. To solve these problems, we propose a lifting system with an alternating rotation mechanism, which takes advantage of the lifting mechanism of a climbing doll. In this paper, we explain the design and control methods of the lifting mechanism and alternating rotation hoist to realize the proposed lifting system. For the moving frame body, we designed and made a mechanism and frame structure to maintain stability of its posture. Performing an operation test in our laboratory and in the field with the proposed system incorporated into an actual unit, we checked the action of the proposed mechanism. In particular, we could confirm in the field test that the postural stability necessary for shooting inspection images could be ensured in an environment with wind speed of 5 m/s and that ascending and descending motions could be successfully performed with the current output of the alternating rotation hoist, even in an environment with a mean wind speed of 10 m/s.
Changes in partner traits drive variation in plant–nectar robber interactions across habitats

The frequency and outcome of biotic interactions commonly vary with environmental conditions, even without changes to community composition. Yet the drivers of such environmentally-mediated change in biotic interactions are poorly understood, limiting our ability to predict how environmental change will impact communities. Studying nectar robbery by stingless bees of Odontonema cuspidatum (Acanthaceae) in a coffee agroecosystem, we documented a temporally consistent difference in nectar robbing intensity between anthropogenic and seminatural habitats. Plants growing in coffee fields (anthropogenic habitat) experienced significantly more nectar robbery than plants growing in forest fragments (seminatural habitat). Using a combination of field surveys and manipulative experiments, we found that nectar robbery was higher in coffee fields primarily due to environmental effects on a) neighborhood floral context and b) O. cuspidatum floral traits. This led to both preferential foraging by nectar robbers in coffee fields, and to changes in foraging behavior on O. cuspidatum that increased robbery. Nectar robbery significantly reduced fruit set in O. cuspidatum. These results suggest that the effects of anthropogenic environmental change on species traits may be more important than its effect on species density in determining how interaction frequency and outcome are affected by such environmental change.
p27(Kip1) in prostate cancer, prognostic value and role in mediating effect of high-dose dihydrotestosterone in LNCaP

p27"p' in prostate cancer: pmgnostic vaiue and role in mediating effect of higb dose dihydrotestosterone in LNCaP. Master of Science, 1999, John Tsihlias, institute of Medical Science, University of Toronto. p27 is a cyclin-dependent kinase inhibitor capable of inducing ce11 cycle arrest. p27 is abundant in multiple humm epithelial tissues, however, the protein is less abundant and its expression more heterogeneous in rnalignancies from these tissues. in a study of archiva1 tumoun from patients with clinically localized adenocarcinorna of the prostate, low p27 predicted shorter disease free survival. Androgen deprivation therapy pnor to surgery tended to increase the p27 level. Low p27 in such nimours was an even stronger predictor of earl y recurrence. G 1 arrest of LNCaP cells by high dose dihydrotestosterone Ieads to a four-fold increase in p27 level-, three-fold increase in p27 bound CO cyclin E complexes, and inhibition of cycl in E-associated kinase activity . These data raise the h ypothesis that changes in pathways that regu late p27 levels may contribute causal1 y to tumour progression and growth modulation of human prostate cancer cells in response to various androgenic stimuli.
Assessment of the risk of soil erosion using RUSLE method and SWAT model at the M’dez Watershed, Middle Atlas, Morocco

The preservation of soil resources is a primary global concern and a permanent challenge for all Mediterranean countries. In Morocco, the capacity of dam reservoirs continues to decline from one year to the next due to the rate of siltation, mainly due to the phenomenon of water erosion. Indeed, the origins of this erosion are generally related to land use planning, deforestation, agricultural practices and low vegetation cover. However, it is imperative to quantify soil erosion and its spatial distribution to achieve sustainable land use and governance of this resource. The SWAT hydro-agricultural model and the integrated RUSLE model were used to assess soil losses and characterize the degraded areas of the M’dez watershed, located in the upper Sebou, north of the Middle Atlas, and extend on an area of 3350 km2. The results obtained during this work show that the average soil losses estimated by the two models are consistent. For the SWAT model, the specific degradation of the watershed is estimated at 3.95 t/ha/year, whereas for the RUSLE model, the average loss of the basin is estimated at 2.94 t/ha/year). However, the use of these two models (SWAT and RUSLE), for the assessment and characterization of degraded areas at the level of Moroccan watersheds, has become a much sought-after approach for good soil conservation management.
Model Selection for Mixture Models Using Perfect Sample

We have considered a perfect sample method for model selection of ﬁnite mixture models with either known (ﬁxed) or unknown number of components which can be applied in the most general setting with assumptions on the relation between the rival models and the true distribution. It is, both, one or neither to be well-speciﬁed or mis-speciﬁed, they may be nested or non-nested. We consider mixture distribution as a complete-data (bivariate) distribution by prediction of missing data variable (unobserved variable) and show that this ideas is applicable to use Vuong’s test for select optimum mixture model when number of components are known (ﬁxed) or unknown. We have considered AIC and BIC based on the complete-data distribution. The performance of this method is evaluated by Monte-Carlo method and real data set, as Total Energy Production.
Evaluating the cost-effectiveness of a mobile decision support tool in Malawi.

Mobile applications are promising tools for strengthening service quality and have been an area of considerable mHealth innovation. Despite growing demand for data to guide policymakers donors and program managers in making sound investments there is a paucity of evidence on the cost-effectiveness of mHealth technologies. To address this gap the HFG Project analyzed a mobile decision support tool with the following objectives: First it aimed to provide a transparent and detailed methodology for categorizing the costs of building deploying and scaling-up mobile decision support tools in Malawi. Second it evaluated the incremental cost-effectiveness of a mobile tool’s use in improving clinical care. Finally the evaluation addressed challenges faced in conducting cost-effectiveness analyses of mHealth interventions when they are scaled up and become multifunctional.
Kronik Böbrek Hastalarında Endotel İşlev Bozukluğu ve Serum Pentraxin-3 Düzeyleri

aım: Cardiovascular diseases are the leading cause of morbidity and mortality in chronic kidney disease (CKD). Inflammation and endothelial dysfunction contribute to the development of cardiovascular disease in CKD. Pentraxin-3 (PTX-3), a new candidate marker for inflammation is expressed in a variety of cell types. We aimed to investigate the relation between plasma PTX-3, serum hs-CRP levels and endothelial dysfunction in CKD. maTERıal and mETHOdS: One hundred and twenty-five patients with CKD were studied. Patients were divided into 5 groups according to their glomerular filtration rate (GFR) as assessed by K/DOQI guidelines. Twenty-five healthy subjects were studied as controls. Venous samples were obtained from all subjects for PTX-3 and hs-CRP levels in addition to detailed metabolic panel. Endothelial dysfunction was assessed from all subjects by flow-mediated dilatation (FMD). RESulTS: FMD levels were significantly decreased in all stages with the higher the stage of CKD, the lower the levels of FMD. Plasma PTX-3 levels of the stage 1-2-3 CKD group were similar to those of the controls, while other groups had significantly higher values (p<0.001). Additionally, hs-CRP levels were significantly increased in all stages of CKD. There was a significant positive correlation between FMD and GFR(r=0.762, p<0.001). There was also a significant negative correlation between FMD and PTX-3 (r=-0.414, p<0.001) as well as between FMD and hs-CRP (r=-0.546, p<0.001). COnCluSıOn: The results suggest that both plasma PTX-3 and hs-CRP levels are associated with endothelial dysfunction in CKD patients. KEY WORdS: Endothelial dysfunction, Pentraxin-3, Chronic kidney disease Yazışma Adresi: mahmut İlker Yılmaz Gülhane Askeri Tıp Akademisi, Nefroloji Bilim Dalı, Ankara, Türkiye Tel : 0 312 304 40 92 Gsm : 0 532 381 54 89 E-posta : mahmutilkeryilmaz@gmail.com Geliş Tarihi : 07.05. 2010 Kabul Tarihi : 18.06. 2010