Miracle-dz/UniFAR-FTUs huggingface dataset:
Single Phase Induction Motor Drive with Restrained Speed and Torque Ripples Using Neural Network Predictive Controller

In industrial drives, electric motors are extensively utilized to impart motion control and induction motors are the most familiar drive at present due to its extensive performance characteristic similar with that of DC drives. Precise control of drives is the main attribute in industries to optimize the performance and to increase its production rate. In motion control, the major considerations are the torque and speed ripples. Design of controllers has become increasingly complex to such systems for better management of energy and raw materials to attain optimal performance. Meager parameter appraisal results are unsuitable, leading to unstable operation. The rapid intensification of digital computer revolutionizes to practice precise control and allows implementation of advanced control strategy to extremely multifaceted systems. To solve complex control problems, model predictive control is an authoritative scheme, which exploits an explicit model of the process to be controlled. This paper presents a predictive control strategy by a neural network predictive controller based single phase induction motor drive to minimize the speed and torque ripples. The proposed method exhibits better performance than the conventional controller and validity of the proposed method is verified by the simulation results using MATLAB software.
Revisiting regulatory T cells in type 1 diabetes

Purpose of review Regulatory T cells (Treg) maintain immune homeostasis and prevent autoimmune disease. This review summarizes the recent advances in Treg knowledge relevant to type 1 diabetes, focusing on Treg signature, antigen specificity and development and function in the face of inflammation. Recent findings Thymus-derived natural regulatory T cells (nTreg) programmed by the transcription factor forkhead box P3 (FOXP3) and peripheral-induced regulatory T cells (iTreg) have largely nonoverlapping T-cell receptor repertoires to self-antigens and jointly contribute to immune homeostasis. Initial reports that CD4+CD25+ (FOXP3+) Treg were impaired in frequency or function in type 1 diabetes have not been confirmed. The Treg-specific demethylated region in the FOXP3 locus in nTreg is, in contrast, methylated in iTreg and conventional T cells (Tconv) and is the only feature that reliably distinguishes activated human nTreg and Tconv. Inflammatory cytokines regulate extrathymic differentiation of nTreg but can also reprogram nTreg into Th17 or Th1 effectors and prevent the differentiation of iTreg. Summary The methylation status of the FOXP3 locus provides a means to re-examine Treg in autoimmune disease. nTreg and iTreg recognize different self-antigens. Shaping of Treg by the cytokine milieu has implications for the application of Treg cell-based immune therapies.
Cytogénétique des carcinomes rénaux [Cytogenetics profiles of renal carcinoma]

Renal carcinomas are histologically and prognostically heterogeneous. Genomic as well as chromosomal studies of these tumors have permitted a better comprehension of molecular mechanisms implicated in their development and progression. The most frequent histological subtypes are characterized by recurrent cytogenetic abnormalities, such as the loss of the chromosome 3 short arm involving a VHL gene copy in clear cell renal carcinomas, or trisomies 7 and 17 in papillary renal cell carcinomas. New histological subtypes like renal carcinomas associated with Xp11.2 translocations have also been individualized. Besides diagnosis, some chromosomal aberrations like the loss of a short arm of chromosome 9 in different renal carcinoma histological subtypes have a worse prognostic impact. The identification of chromosomal shuffles contributes in backing histological diagnosis and in precising the individual prognosis of patients. This review describes chromosomal abnormalities associated to renal carcinomas and their impact for an accurate classification of these tumors and the evaluation of their prognosis. Les carcinomes renaux sont un groupe heterogene de tumeurs sur le plan histologique et pronostique. Les etudes genomiques et chromosomiques de ces cancers ont permis de mieux comprendre les mecanismes moleculaires impliques dans le developpement et la progression tumorale. Les sous-types histologiques les plus frequents sont caracterises par des anomalies cytogenetiques recurrentes, telles que la perte du bras court d'un chromosome 3 emportant une copie du gene VHL dans les carcinomes renaux a cellules claires ou les trisomies 7 et 17 dans les carcinomes renaux tubulo-papillaires. De nouveaux sous-types histologiques comme les carcinomes renaux associes aux translocations impliquant la region Xp11.2 ont egalement pu etre individualises. Parallelement au diagnostic, certaines anomalies chromosomiques comme la perte du bras court d'un chromosome 9 ont un impact pronostique pejoratif pour differents sous-types histologiques de carcinomes renaux. La mise en evidence des remaniements chromosomiques contribue ainsi a etayer le diagnostic histologique et a preciser le pronostic individuel des patients. Cette revue decrit les anomalies chromosomiques associees aux carcinomes renaux et leur impact pour la classification precise de ces tumeurs et l'evaluation de leur pronostic.
Estrogen Impact on Autoimmunity Onset and Progression: the Paradigm of Systemic Lupus Erythematosus

 Abstract— Autoimmune diseases (ADs) are thought to result from a combination of genetics, environmental triggers, and stochastic events. Female prevalence in ADs and the effects of sex hormones on the immune system support a role for these hormones in the pathogenesis of ADs. Systemic Lupus Erythematosus (SLE) is a prototypical AD with a significant predominance in women, and estrogen is likely to play a pathogenic role in this disease. Estrogen's primary effects are mediated by transcription activity of the intracellular estrogen receptors (ERs), ERα and ERβ, to produce genomic effects. Rapid estrogen-mediated effects (referred to as non-genomic) are triggered through the membrane-associated ER (mER) activation and are independent of transcription pathways and protein synthesis. Depending on cell type, hormone concentration, and receptor subtype, estrogens may exert both pro-inflammatory and anti-inflammatory responses. In addition to endogenous estrogens, the immune system can be targeted by natural or synthetic chemicals with estrogenic activity, i.e., the estrogenic endocrine disruptors (EEDs), which are widely found in the environment. EEDs could trigger or alter the onset and/or progression of ADs by modifying the function of immune cells. Estrogens can be also administered through medications (oral contraceptives and hormone replacement therapy). Here, we provide a review of the in vivo and in vitro effects of endogenous and exogenous estrogens on the immune system, focusing on the evidence of association between estrogen exposure and SLE. Index Terms—autoimmune diseases, estrogens, estrogenic endocrine disruptors, Systemic Lupus Erythematosus, immune system, lymphocytes.
3D stroke reconstruction and cursive script recognition with magnetometer-aided inertial measurement unit

In this paper, we present a novel stroke reconstruction algorithm for 3D cursive script using an inexpensive accelerometer and magnetometer. By imposing constraints based on ergonomics and habitual motions, the proposed algorithm can accurately estimate the orientation of a handheld device under both static and dynamic conditions. Then, the gravitational force is subtracted from the measured acceleration force for the stroke-induced acceleration, the values of which are integrated twice over time to obtain a position trajectory. The reconstruction performance is evaluated by comparing estimated stroke trajectories from a magnetometer-aided inertial measurement unit (mIMU) with those from an optical motion tracking system for alphanumeric cursive scripts. Furthermore, the recognition rates of the proposed algorithm and other conventional algorithms are compared. The experimental results reveal high accuracy in both stroke reconstruction and recognition rates.
Impulsive‐compulsive spectrum behaviors in pathologically confirmed progressive supranuclear palsy

There is growing awareness of impulsive‐compulsive spectrum behaviors (ICBs) in patients with Parkinson's disease (PD) treated with dopamine replacement therapy (DRT). These include pathological gambling, hypersexuality, compulsive shopping, binge eating, punding and compulsive use of DRT, or dopamine dysregulation syndrome. In PD, difficulties exist in separating the effects of DRT from the underlying disease process and aberrant dopaminergic systems in determining the aetiology of ICBs. Recent reports of ICBs associated with dopamine agonist use for conditions other than PD may suggest a significant etiological role for these medications, but currently published cases thus far lack pathological confirmation of diagnoses. We present three cases of pathologically confirmed progressive supranuclear palsy who developed ICBs in association with dopamine agonist use. Pathological comparisons between these three cases and other case series of progressive supranuclear palsy are made. © 2010 Movement Disorder Society
Revisiting the ISO standard for dialogue act annotation

Based on experiences using the ISO standard for dialogue act annotation (ISO 24617-2:2012), this paper proposes to correct certain deﬁciencies in the standard, and discusses some extensions that would increase the standard usefulness and usability. More speciﬁcally, it is suggested to add the annotation of non-functional segments that are relevant for the accurate annotation of some feedback acts and speech editing acts, and to import devices from the newly established ISO standard for the annotation of discourse relations (ISO DR-Core) in order to improve the annotation of rhetorical relations between dialogue acts. The latter kind of extension is argued to be interesting for also joint annotation of different kinds of semantic information by combining different annotation schemes.
Quality of life outcomes following surgical treatment of Parkinson's disease

We assessed the impact of surgical treatment of Parkinson's disease on quality of life using generic quality of life instruments and utility scores. The Medical Outcomes Study short form health survey SF‐36 and Parkinson's Disease Questionnaire PDQ‐39 were used before and 3–6 months after surgery to assess quality of life, and the results were converted into utility valuations. Ninety‐seven patients were studied; 33 underwent unilateral thalamotomy, 33 unilateral pallidotomy, 20 bilateral pallidotomy, six subthalamic nucleus (STN) lesions, four mixed lesions, and in one case bilateral STN stimulation. All dimensions of the SF‐36 except role mental and mental health showed statistically significant improvement following surgery. The PDQ‐39 recorded significant improvements in the mobility, stigma, and bodily discomfort dimensions. The rating scale and time trade‐off scales showed statistically significant gains in utility of 8% and 3%, respectively. Gains were particularly marked in the bilateral pallidotomy group. Differences in patient characteristics and selection made direct comparisons between procedures unreliable. Quality of life in patients with advanced Parkinson's disease is amenable to measurement; such measurement provides tentative evidence of significant gains in quality of life following some neurosurgical procedures. © 2001 Movement Disorder Society.
Bouton renewal patterns in rat hindlimb cortex after thoracic dorsal funicular lesions

The transneuronal effect of bilateral, dorsal funicular lesions (T 12) on the frequency of boutons on cells in layer IV of hindlimb cortex was studies. Adult rats were utilized 1, 2, 3, 7, 14, 30, 45, 60, 90, or 120 days postoperative (DPO), and tissue was processed for the light microscopic visualization of silver‐impregnated boutons (Rasmussen method). Bouton counts were taken on soma, or along 5‐ and 10‐μm segments of proximal dendrite branching from soma. The soma diameter also was measured on those neurons chosen for bouton counts on the circumference of the soma. Statistically significant, increased afferentation on soma and proximal dendrite occurred during the first postlesion week relative to longer survival times; bouton counts on the proximal dendrite showed a trend (not statistically significant) toward increases above normal. These data mirror similar, consistent increases in bouton counts reported in thalamic ventroposterolateral nucleus of these same cases. At 14 DPO, bouton counts on the soma decreased below normal (P<0.005) and, except at 60 DPO, remained so through 120 DPO (P<0.025). Bouton counts on the proximal dendrite also decreased below normal at 14 DPO (P<0.005), thereafter exhibiting either periodic (along 5‐7μm) or extended (along 10‐7mu;m) periods in significant decreases from normal. Correlations in lesioned cases between the number of boutons on the soma and either bouton counts on proximal dendrite or soma diameter were positive and statistically significant (P<0.005 in all correlations). Possible anterograde (via the dorsal column‐medial lemniscal system) and/or retrograde (via the corticospinal tract) transneuronal mediation of these effects in hindlimb cortex is discussed.
Phyllodes Tumors of the Breast: A Review of 32 Cases

Most general surgeons involved in breast cancer care have limited experience with phyllodes tumors. We analyzed a comprehensive database incorporating 8567 breast cancer cases treated surgically in the Tulsa, Oklahoma, region between 1969 and 1993. This yielded 32 cases of phyllodes tumors (0.37%) in 31 patients. The median age was 57 years (range, 18–91). There were 9 low-grade (28%), 2 intermediate-grade (6%), and 21 high-grade (66%) lesions. Size distribution consisted of 23 (72%) lesions 5 cm or less and 9 (28%) greater than 5 cm (mean, 3; range, 1.2–17.5 cm). Of 137 resected nodes in 13 patients, none were positive for metastatic disease. Surgical management consisted of wide excision or mastectomy. No patients received adjuvant chemoradiation therapy. The disease-free, locoregional disease-free, and overall mean survival rates were 80, 81, and 97 months, respectively. Ten-year disease-free survival (DFS), locoregional disease-free survival (LRDFS), and overall survival (OS) rates were 66, 72, and 55 per cent, respectively. Although there was a tendency toward a higher rate of locoregional recurrences and metastases with high-grade lesions, this was not statistically significant and did not affect DFS, LRDFS, or OS rates. Similarly, size of lesion did not affect DFS, LRDFS, or OS rates. Three patients (9.6%) had metastatic disease at presentation, and a further two (6.4%) developed metastases during follow-up. Overall, nine (28.1%) recurrences developed in eight patients, seven locoregional and two distant. Four patients (12.9%) died with evidence of disease. These findings indicate prolonged survival in this patient population with cystosarcoma phyllodes. Wide local excision of primary and recurrent lesions remains the mainstay of therapy. Neither regional lymph node dissection nor adjuvant chemoradiation adds significant benefit.
Permanently on Call: The Effects of Social Pressure on Smartphone Users' Self-Control, Need Satisfaction, and Well-Being

While many smartphone users experience social pressure to be available, only some perceive this as a burden. It was hypothesized that this form of social pressure is especially detrimental when it reduces self-control and hinders need satisfaction. Study 1 experimentally tested whether the fulfillment of intrinsic needs (i.e., autonomy, competence, and relatedness) in mobile communication mediates these associations. Results show that social pressure negatively affected autonomy and competence, but did not influence relatedness. Repeated-measures data from Study 2 suggest that social pressure leads to self-control failure, which is associated with reduced competence. This research is the first to develop and test a theoretical model of the effects of social pressure to be available on self-control, need satisfaction, and individuals' well-being.
Costs and cost-effectiveness of a clinical intervention to increase mammography utilization in an inner city public health hospital.

BACKGROUND Studies have demonstrated the cost-effectiveness of screening women for breast cancer; however, the cost-effectiveness of strategies to motivate women to receive breast cancer screening has been less well studied. METHODS A total of 196 women, aged 50 to 74, who were enrolled in a public health hospital clinic, were noncompliant with mammography screening, and had at least one routine clinic appointment during the study period (15 months) were entered into a randomized, controlled trial of a motivational intervention to increase mammography rates. Costs were captured via a modified Delphi technique, accounting records, sampling of staff time logs, and an estimation of miscellaneous and overhead costs. Summary costs were calculated using Excel spread sheets. RESULTS Overall, 49% of women who received the intervention had a mammogram within 8 weeks of an index visit compared with 22% of control women. Calculation of the cost-effectiveness of the project showed an additional cost of $151 (1996 U.S.$) for each woman receiving the intervention and $559 for each additional woman motivated to receive a mammogram. CONCLUSIONS Cost tracking and cost-effectiveness analysis can be done when intervening in a clinical setting, thereby allowing clinics to make informed decisions about implementing programs to increase motivation of their patients to receive screening.
Imaging in the Diagnosis and Monitoring of Children with Idiopathic Scoliosis

The paper reviews the current imaging methods in the diagnosis and monitoring of patients with adolescent idiopathic scoliosis. Radiography is generally used in the initial diagnosis of the condition. Postero-anterior erect full spine radiograph is generally prescribed, and is supplemented by lateral full spine radiograph when indicated. To reduce the radiation hazard, only the area of interest should be exposed, and follow-up radiographs should be taken with as few projections as possible. When available, EOS® stereoradiography should be used. The radiation of the microdose protocol is 45 times less than that of the conventional radiography. Surface topography offers another approach to monitoring changes of curvatures in AIS patients. Recently, 3D ultrasound has been found to be able to measure the Cobb angle accurately. Yet, it is still in the early developmental stages. The inherent intrinsic and external limitations of the imaging system need to be resolved before it can be widely used clinically. For AIS patients with atypical presentation, computed tomography (CT) and/or magnetic resonance imaging (MRI) may be required to assess for any underlying pathology. As CT is associated with a high radiation dose, it is playing a diminishing role in the management of scoliosis, and is replaced by MRI, which is also used for pre-operative planning of scoliosis. The different imaging methods have their limitations. The EOS® stereoradiography is expensive and is not commonly available. The surface topography does not enable measurement of Cobb angle, particularly when the patient is in-brace. The 3D ultrasound scanning has inherent intrinsic technical limitation and cannot be used in all subjects. Radiography, however, enables diagnosis and monitoring of the adolescent idiopathic scoliosis (AIS). It is thus the gold standard in the evaluation and management of scoliosis curves.
Le projet symogih.org, un système modulaire de gestion de l'information historique

Le projet symogih.org a concu une plateforme modulaire et ouverte pour heberger les informations geo-historiques. La plateforme, accessible par le web, permet aux chercheurs de partager leurs donnees et leurs textes dans un environnement collaboratif et de produire ainsi des donnees structurees concernant tous les champs historiques. La richesse et l'heterogeneite de l'information partagee requiert un modele generique de donnees qui a ete concu avec la methode Merise et integre dans une base de donnees relationnelles PostgreSQL a laquelle les utilisateurs se connectent par une application web. En parallele, le projet symogih.org a deploye un environnement pour analyser, partager et publier des textes encodes en XML/TEI en utilisant la plateforme eXist-db. L'annotation semantique des entites nommees et des unites de connaissance est accomplie en reliant les balises semantiques definies en ligne avec la Text Encoding Initiative (TEI) aux ressources creees dans la base de donnees relationnelles. L'ensemble du systeme est interoperable et en cours d'alignement avec d'autres ressources du web des donnees et referentiels d'autorite. Une portion croissante des informations sont accessibles au format RDF par un point d'acces SPARQL par un point d'acces SPARQL, permettant une interrogation des donnees du projet symogih.org et, en meme temps, de celles issues d'autres entrepots du web des donnees.
” Sex is a Divine Gift ” : For whom ? Evidence from the Manila contraceptive ban

We analyze the tradeoff between child quantity and quality in developing countries by estimating the effect of family size on child’s education in urban Philippines. To isolate exogenous changes in family size, we exploit a policy shock that occurred in the late 1990s when the mayor of Manila enacted a municipal ban on modern contraceptives. Since other comparable cities in the Manila metropolitan area where not affected by the ban, this allows us to implement a differencein-difference estimation of the effect of family size. Our analysis relies on census and survey data and focuses on two dimensions : the effect of the ban on fertility and family size and the effect of family size on the probability for a child be held back in school. Our results indicate that the contraceptive ban led to a significant increase in family size, which had a sizable, negative impact on child education.
Changes in the Lactobacillus community during Ricotta forte cheese natural fermentation

The loss of microbial biodiversity due to the increase in large‐scale industrial processes led to the study of the natural microflora present in a typical little known dairy product. The community of lactobacilli was studied in order to understand the natural fermentation of Ricotta forte cheese. The combined use of RAPD analysis, 16S rDNA sequencing and physiological tests allowed 33 different strains belonging to 10 species of Lactobacillus to be characterized. RAPD analysis revealed the heterogeneity of both the Lact. kefiri and Lact. paracasei species. The sequence analysis of the large 16S/23S rRNA spacer region enabled Lact. plantarum to be distinguished from Lact. paraplantarum, two closely related species belonging to the Lact. plantarum group. The recovery of strains endowed with interesting physiological characteristics, such as strong stress resistance, could improve technological and/or organoleptic characteristics of Ricotta forte cheese and other fermented foods.
In-situ-displaydrone: facilitating co-located interactive experiences via a flying screen

This demo paper describes a drone-based display that has a projector and a canvas mounted to one and the same drone. It is aimed for indoor in-situ deployments, enabling new forms of interactive entertainment and visual experiences in co-located settings. In addition the paper describes a large size flying display with a diameter of 3,5 meters for outdoor use. We discuss technical setups and early test deployments of the displays.