Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Nonsurgical Spinal Decompression Treatment on the Level of Pain and Quality of Life in Patients with Cervical or Lumbar Disc Herniation: A Retrospective Observational Study

Background: This study aims to statistically analyze and compare the curative effect and satisfaction level between typical traditional Korean medicine treatment and nonsurgical spinal decompression treatment. Methods: Of the patients who were diagnosed with the cervical or lumbar herniated intervertebral disc at the Department of Acupuncture and Moxibustion Medicine at the Daejeon Korean Medicine Hospital from April 14th to August 25th, 2019, this study retrospectively analyzed the medical records of 31 patients who underwent nonsurgical spinal decompression treatment and traditional Korean medicine (assigned to Group A) and another 31 patients who received typical traditional Korean medicine alone (assigned to Group B). The clinical data were analyzed using IBM SPSS Version 23.0. Results: No statistically significant differences appeared in terms of sociodemographic, condition, and therapeutic characteristics, except whether the patient received Western medicine treatment, before or after a treatment with traditional Korean medicine. Group A exhibited higher variations in numeric rating scale, EuroQol- 5 dimension and EuroQol visual analogue scale scores compared to Group B as determined by independent sample t test and analysis of covariance. In addition, the satisfaction score of Group A was higher than that of Group B The result of cross analysis revealed that desire for continued treatment in Group A was higher than that of Group B. Conclusion: This retrospective observational study showed that the patients with nonsurgical spinal decompression treatment reported a greater reduction in pain, improved quality of life and satisfaction than patients receiving typical traditional Korean medicine.
Investigating large methane enhancements in the U.S. San Juan Basin

In 2014, a satellite-based map of regional anomalies of atmospheric methane (CH4) column retrievals singled out the fossil fuel rich San Juan Basin (SJB) as the biggest CH4 regional anomaly (“hot spot”) in the United States. Over a 3-week period in April 2015, we conducted ground and airborne atmospheric measurements to investigate daily wind regimes and CH4 emissions in this region of SW Colorado and NW New Mexico. The SJB, similar to other topographical basins with local sources, experienced elevated surface air pollution under low wind and surface temperature inversion at night and early morning. Survey drives in the basin identified multiple CH4 and ethane (C2H6) sources with distinct C2H6-to-CH4 emission plume ratios for coal bed methane (CBM), natural gas, oil, and coal production operations. Air samples influenced by gas seepage from the Fruitland coal formation outcrop in La Plata County, CO, had enhanced CH4, with no C2-5 light alkane enhancements. In situ fast-response data from seven basin survey flights, all with westerly winds, were used to map and attribute the detected C2H6 and CH4 emission plumes. C2H6-to-CH4 plume enhancement correlation slopes increased from north to south, reflecting the composition of the natural gas and/or CBM extracted in different parts of the basin. Nearly 75% of the total detected CH4 and 85% of the total detected C2H6 hot spot were located in New Mexico. Emissions from CBM and natural gas operations contributed 66% to 75% of the CH4 hot spot. Emissions from oil operations in New Mexico contributed 5% to 6% of the CH4 hot spot and 8% to 14% of the C2H6 hot spot. Seepage from the Fruitland coal outcrop in Colorado contributed at most 8% of the total detected CH4, while gas venting from the San Juan underground coal mine contributed <2%.
Relationship between Very Fine Root Distribution and Soil Water Content in Pre- and Post-Harvest Areas of Two Coniferous Tree Species

Tree root system development alters forest soil properties, and differences in root diameter frequency and root length per soil volume reflect differences in root system function. In this study, the relationship between vertical distribution of very fine root and soil water content was investigated in intact tree and cut tree areas. The vertical distribution of root density with different diameter classes (very fine <0.5 mm and fine 0.5–2.0 mm) and soil water content were examined along a slope with two coniferous tree species, Cryptomeria japonica (L.f.) D. Don and Chamaecyparis obtusa (Siebold et Zucc.) Endl. The root biomass and length density of very fine roots at soil depth of 0–5 cm were higher in the Ch. obtusa intact tree plot than in the Cr. japonica intact plot. Tree cutting caused a reduction in the biomass and length of very fine roots at 0–5 cm soil depth, and an increment in soil water content at 5–30 cm soil depth of the Ch. obtusa cut tree plot one year after cutting. However, very fine root density of the Cr. japonica intact tree plot was quite low and the soil water content in post-harvest areas did not change. The increase in soil water content at 5–30 cm soil depth of the Ch. obtusa cut tree plot could be caused by the decrease in very fine roots at 0–5 cm soil depth. These results suggest that the distribution of soil water content was changed after tree cutting of Ch. obtusa by the channels generated by the decay of very fine roots. It was also shown that differences in root system characteristics among different tree species affect soil water properties after cutting.
Emotional Analysis of Cigarette Consumers Based on CNN and BiLSTM Deep Learning Model

Cigarette online reviews can truly reflect the word-of-mouth of cigarettes, and help cigarette industrial and commercial enterprises to understand consumers’ cigarette use experience and cigarette word-of-mouth dynamics. In order to extract effective consumer experience information from massive online reviews of cigarette consumption, this paper studies the text sentiment analysis of cigarette online reviews. This paper presents a feature fusion model of convolutional neural network and BiLSTM. Experimental results show that the proposed feature fusion model effectively improves the accuracy of text classification. The model can provide new insight for the evaluation of cigarette management, dynamically monitor the change of consumers’ emotion, and grasp the trend of consumers’ emotion in the tobacco market environment in time.
Effect of high temperature ECAP process on microstructure and mechanical properties of Ti-5553 alloy

Excellent mechanical properties are the key to improve the erosion resistance of materials. Superplastic deformation process ECAP is a new heat treatment method which can refine grain size, improve the microstructure of materials and the comprehensive mechanical properties of materials. In this paper, the microstructure of Ti-5553 alloy treated by ECAP process and Ti-5553 alloy without ECAP process were observed, and the effect of high temperature ECAP process on the microstructure of Ti-5553 alloy was discussed. The effect of high temperature ECAP process on the mechanical properties of Ti-5553 alloy was studied by tensile test, and the effect of high temperature ECAP process on refining microstructure and improving mechanical properties of Ti-5553 alloy was discussed mechanism.
Preparation of Pt/SiO2 Ultra-fine Particles in Reversed Micelles and Their Catalytic Activity

Ultra fine Pt particles supported on SiO2 was successfully prepared by the hydrolysis of tetraethoxysilane in the same reversed micellar solution of previously mono-dispersed Pt particles. Formed Pt/SiO2 surface was partly covered with the residue of surfactant, which caused the inhibition of hydrogen adsorption as well as hydrogenation of propene.
Improving Convolutional Neural Network Expression via Difference Exponentially Linear Units

Convolutional Neural Network (CNN) has been applied to various tasks with great success. Adding an activation function is an important way to introduce nonlinearity into convolutional neural networks. The commonly used activation functions mostly use different forms of negative feedback for the negative input, however, some researchers have recently proposed positive feedback methods for the negative input such as Concatenated Rectified Linear Units (CReLU) and Linearly Scaled Hyperbolic Tangent (LiSHT) and achieved better performance. To explore this idea further more, we propose a new activation function called Difference Exponentially Linear Unit (DELU). The proposed DELU activation function can optionally provide positive and negative feedback for different values of negative inputs. Our experimental results on the commonly used datasets such as Fashion Mnist, CIFAR10, and Imagenet show that DELU outperforms other six activation functions, Leaky ReLU, ReLU, ELU, SELU, Swish, SERLU.
Gastric carcinosarcoma with rhabdomyosarcomatous differentiation: a case report and literature review

Gastric carcinosarcoma with rhabdomyosarcomatous differentiation is a rare tumor. Herein, we report the case of a 34-year-old man with a history of dysphagia, upper abdominal fullness, and poor appetite. Endoscopic findings showed a large friable mass that originated from the gastric cardia and lesser curvature of the high body. Consequently, radical total gastrectomy with Roux-en-Y esophagojejunostomy was performed. Histopathological analysis of the resected specimen revealed that the mass had invaded the serosa without regional lymph node metastasis; moreover, the tumor was positive for desmin and myogenin. Finally, we conclude this report with literature review and discussion.
Exploratory-Data and Statistical Analyses of AB070597, an Amino Acid/Peptide Complex, on Blood-Serum Creatinine Concentration and Estimated Glomerular Filtration Rate: A Non-Randomized Pilot Trial of Five Humans with Declining Renal Function

ABSTRACT Background: Chronic kidney disease (CKD) develops from persistent, irremediable loss of renal function (RF). Animal studies show that dietary supplement, AB070597, an amino acid/ peptide complex, can stabilize, and in some instances, reverse CKD. Previous human CKD studies demonstrate that dietary treatment with specific keto acids and amino acids can lower blood-serum creatinine concentration (SCr) and increase glomerular filtration rate (GFR). This pilot trial was performed to determine whether a future randomized controlled human clinical trial of AB070597’s effect on CKD was justified. Methods: The trial was structured as a consecutive case series to evaluate whether oral treatment with AB070597 could slow CKD progression, as gaged by SCr, and estimated glomerular filtration rate (eGFR). Eligibility requirements: Non-diabetic white males under current medical care in the United States, diagnosed with CKD, or with histories of increasing SCr and declining eGFR, resulting from CKD or natural consequence of aging. Exclusion criteria: Concurrent or suspected comorbidities unrelated to CKD. Participants ingested 6-g bi-daily doses of AB070597 for periods up to 24 months. SCr was measured and eGFR calculated at approximate tri-monthly intervals. Results: Results were presented as individual-participant and group SCr and eGFR vectors, and initial-data-analysis diagrams. Treatment reversed SCr slopes from positive to negative, and eGFR slopes from negative to positive. When individual participant’s median monthly eGFR rate-of-change (positive) was compared with the median monthly eGFR rate-of-change (negative) in a sample of 2870 humans with CKD, differences were significant in favor of the AB070597 treatment group in 4 of 5 participants: (P = 0.0625, 95% CI: 0.368-8.368), (P = 0.0313, 95% CI: 0.368-1.038), (P = 0.0039, 95% CI: 0.368-0.698), (P = 0.0010, 95% CI: 0.118-2.868), (P <0.0001, 95% CI: 0.368-10.370). Conclusion: Oral AB070597 treatment produced an apparently favorable change in CKD trajectory in 4 humans and in 1 with naturally age-related declining RF. The magnitude and direction of change hint that treatment may have had a beneficial effect on CKD progression and age-related RF. In and of themselves, this pilot trial’s results seem to favor CKD treatment with AB070597, but because there was no randomization, no control group, and a small sample size , it is not possible to extend results beyond its bounds. They do, however, support the rationale for a future randomized controlled trial
Personality withe refrence to Tribal and Non-tribal college students

Aim of the Research is to find out the personality among types of students, gender and types of faculty. So investigator selected three groups one is types of students second is gender and last one is types of faculty. All groups have 240 peoples. Data were collected from Tapi districts. Scale was use for data collection is personal datasheet and personality scale developed by Singh and Singh (2011), 2x2x2 factorial design was used and data were analysis by ‘F’ test. Result show, type of students was no any significant impact on the personality of tribal and Non-tribal college students. Gender was no any significant impact on the personality of male and female college students. Type of faculty was no any significant impact on the personality of arts and science college students. The interaction between types of students and gender was significant effect on personality (AxB). The interaction between types of students and types of faculty was significant effect on personality (AxC). The interaction between gender and types of faculty was no significant effect on personality (BxC). The interaction between types of students, gender and types of family was no significant effect on personality (AxBxC).
Subcellular microRNAs in diabetic cardiomyopathy

Cardiovascular complications are the leading causes of diabetes-related morbidity and mortality. The high incidence and poor prognosis of heart failure in diabetic patients have been associated, in part, to the presence of an underlying cardiomyopathy characterized by cardiac hypertrophy, cardiomyocytes apoptosis, and ﬁbrosis. It has been unclear about the mechanism that connects diabetes mellitus to the development of cardiovascular dysfunction. Micro(mi)RNAs represent a class of small, 18- to 28-nucleotide-long, non-coding RNA molecules. MiRNAs typically suppress gene expression at the post-transcriptional levels by binding directly to the 3'-UTR of the target mRNAs in the cytoplasm. Interestingly, recent studies suggest that miRNAs may also regulate gene expression in a positive manner. Our recent studies have shown that subcellular miRNAs, such as cytosol-, mitochondria- and nucleus-localized miRNAs, were dramatically dysregulated in diabetic cardiomyopathy. Specifically, cytoplasm localized miRNAs regulate genes expression in a post-transcriptional manner. Nuclear localized miRNAs regulate gene transcription or chromosomal reconstruction through the non-canonical mechanism. Mitochondrial miRNAs stimulate, rather than repress, the translation of specific mitochondrial genome-encoded transcripts. By reviewing these latest discovered functions of subcellular miRNAs in diabetic animal models, we identified new mechanistic insights for diabetic cardiomyopathy. Understanding the nature of subcellular miRNAs will provide new therapeutic targets against diabetes-associated cardiac complications in the near future.
Blood coagulation status after transcatheter aortic valve implantation between the patients with vitamin k antagonist and direct oral anticoagulants

Ischemic stroke after transchatheter aortic valve implantation (TAVI) was recognized. Previous study showed that the median time of a stroke was 2.0 days (IQR, 1.0–5.0) after TAVI. One of the main mechanisms for ischemic stroke after TAVI was hyper-coagulation activity associated with TAVI procedure. However, the change of coagulation status in patients with oral anticoagulant (OAC) therapy was not investigated fully. We investigated the difference of blood coagulation parameters between the patients with vitamin K antagonist (VKA) and those with direct oral anticoagulants (DOAC). We enrolled 253 patients underwent transfemoral TAVI between February 2017 and March 2019 in our hospital. Of 253 patients, 71 patients (age: 85, male: 20%) took OAC therapy (VKA: 21 patients, DOAC: 50 patients). Patients who took apixaban was 32 patients, rivaroxaban was 7, edoxaban was 11. Prothrombin activation fragment 1+2 (F1+2) as a molecular marker of thrombin generation, thrombin-anti-thrombin complex (TAT) as a marker of thrombin neutralization, soluble fibrin monomer complex (SFMC) as a marker of thrombophilia and fibrin/fibrinogen degradation product (FDP) as a marker of fibrinolysis were measured before and immediately after TAVI, and on 1 and 2 day postoperatively. We also assessed ischemic stroke after TAVI between 2 groups according to BARC-2 criteria. In patients with VKA, the value of PT-INR the day before TVAI was 1.2 (1.1–1.4). The level of F1+2 in patients with VKA was significantly greater on day 0 postoperatively than those with DOAC [855 pmol/l (595–1135) vs 614 pmol/l (452–774) P=0.003]. The level of SFMC in patients with VKA was significantly greater on day 0 postoperatively than those with DOAC [37.4 μg/ml (17.3–64.5) vs. 15.7 μg/ml (8.8–27.3) P=0.002]. The level of FDP in patients with VKA was significantly greater on day 0 postoperatively than those with DOAC [VKA: 5.8 μg/ml (3.8–7.9), DOAC: 4.0 μg/ml (3.1–5.3) P=0.023]. There were no patients with ischemic stroke among 2 groups. This study revealed that coagulation activity was increased after TAVI. Furthermore, the coagulation activity in patients with VKA was significantly higher than that with DOAC at especially immediately after TAVI. Careful attention should be paid to hyper-coagulation status after TAVI in patients with VKA. Type of funding source: None
Circulating miR-133b and miR-21: potential non-invasive diagnostic biomarkers of coronary artery disease

While coronary artery disease (CAD) has become a major threat worldwide, the timely biomarker-based early diagnosis of CAD remains a major unmet clinical challenge. We aimed towards assessing the level of circulatory microRNAs as candidates of novel biomarkers in early diagnosis of CAD. A total of 147 subjects were recruited from Delhi and surrounding regions which includes 78 subjects with angiographically proven CAD, 15 pre-atherosclerotic normal coronary artery (NCA) subjects and 54 healthy individuals. Quantitative real-time PCR assays were performed using total RNA isolated from plasma of CAD patients and healthy individuals in order to measure the relative expression profiles of circulating miR-133b and miR-21. The severity level of the disease in each individual was assessed on the basis of number of diseased vessels involved and extent of stenosis. MiR-133b was found to be significantly downregulated (p<0.05) by 4.6 fold whereas miR-21 was significantly upregulated (p<0.05) by ∼2 fold in plasma samples of CAD patients as compared to healthy individuals. Importantly, both the miRNAs showed an association with disease severity as miR-133b was downregulated by 8.45 fold in acute coronary syndrome (ACS), 3.38 fold in Stable angina (SA) and 2.08 fold in NCA. MiR-21 was upregulated by 2.46 fold in ACS, 1.90 fold in SA and 1.12 fold in NCA. Moreover, miR-133b could significantly differentiate subjects with ST-elevation myocardial infarction (STEMI) from Non-STEMI. Both the miRNAs exhibited a noteworthy diagnostic potential as translated through an upstanding sensitivity and specificity. MiR-133b showed an area under the curve (AUC): 0.80 with 75.6% sensitivity and 76% specificity at recommended optimal cut-off point of 14.0 whereas, miR-21 showed and AUC value of 0.79 with 72.2% sensitivity and 69.4% specificity at optimal cut-off point of 5.59 as assessed by receiver operating characteristics (ROC) curve analysis. The reduced expression of miR-133b and elevated expression level of miR-21 in plasma suggest their significant role in the pathophysiology as well as their implication towards the individual's susceptibility in developing CAD. Thus, we conclude that these two circulating miRNAs could be possible candidates of non-invasive biomarkers in the early prediction and diagnosis of CAD. Type of funding source: Other. Main funding source(s): Department of Science and Technology, New Delhi, India; University Grant Commission (JRF/SRF Fellowship: Ref no. 22/12/2013(ii)EU-V
Bijels: a new class of soft materials

Bicontinuous interfacially jammed emulsion gels (‘bijels’) were proposed in 2005 as a hypothetical new class of soft materials in which interpenetrating, continuous domains of two immiscible fluids are maintained in a rigid state, by a jammed layer of colloidal particles at their interface. Such gels should have unusual material properties relevant to catalysis and other applications. Although initially proposed on the basis of computer simulation, the existence of bijels has since been confirmed in the laboratory. However, a wide gap remains between the simulated and the experimental systems. This leaves room for continuing debate on the cause of stability in these materials; in particular, it is not known whether an attraction between the colloidal particles is essential for stability.
Toughening of a trifunctional epoxy system. II. Thermal characterization of epoxy/amine cure

The cure of a trifunctional epoxy resin with an amine coreactant was studied using two thermal analysis techniques: differential scanning claorimetry (DSC) and dynamic mechanical thermal analysis (DMTA). These techniques were used to monitor the development of both the thermal and mechanical properties with cure. Detailed kinetic analysis was performed using a variety of kinetic models: nth order, autocatalytic, and diffusion-controlled. The reaction was found to be autocatalytic in nature during the early stages of cure while becoming diffusion-controlled once vitrification had taken place. By combining the results obtained from DSC and DMTA, the degree of conversion, at which key events such as gelation and vitrification take place, were determined. A TTT diagram was constructed for this epoxy/amine system showing the final properties that can be achieved with the appropriate cure history. © 1996 John Wiley & Sons, Inc.
Resonance-induced hydrogen bonding at sulfur acceptors in R1R2C=S and R1CS2- systems

The hydrogen-bond acceptor ability of sulfur in C~S systems has been investigated using crystallographic data retrieved from the Cambridge Structural Database and via ab initio molecular orbital calculations. The RIR2C=S bond lengths span a wide range, from 1.58 in pure thiones (R1 = R2 = Csp 3) to 1.75/~ in thioureido species (R1 = R2 = N) and in dithioates ---CS~-. The frequency of hydrogen-bond formation at =S increases from 4.8% for C=S _~ 1.63/~ to more than 70% for C~S > 1.70/~ in uncharged species. The effective electronegativity of S is increased by conjugative interactions between C~S and the lone pairs of one or more N substituents (R1R2): a clear example of resonance-induced hydrogen bonding. More than 80% of S in ---CS 2 accept hydrogen bonds. C~S. -. H--N,© bonds are shown to be significantly weaker than their C==O . H--N,© analogues by (a) comparing mean S.H and O.H distances (taking account of the differing non-bonded sizes of S and O and using neutron-normalized H positions) and (b) comparing frequencies of hydrogen-bond formation in 'competitive' environments, i.e. in structures containing both C~S and C==O acceptors. The directional properties and hydrogen-bond coordination numbers of C=S and C==O acceptors have also been compared. There is evidence for lone-pair directionality in both systems, but ~S is more likely (17% of cases) than ~ (4%) to accept more than two hydrogen bonds. Ab initio calculations of residual atomic charges and electrostatic potentials reinforce the crystallographic observations.