Miracle-dz/UniFAR-FTUs huggingface dataset:
The Role of Coherent Detection

Many interesting astronomical objects, such as galaxies, molecular clouds, PDRs, star - forming regions, protostars, evolved stars, planets, and comets, have rich submillimeter spectra. In order to avoid line blending, and to be able to resolve the line shape, it is often necessary to measure these spectra at high resolution. This paper discusses the relative advantages and limitations of coherent and direct detection for high resolution spectroscopy in the submillimeter and far - infrared. In principle, direct detection has a fundamental sensitivity advantage. In practice, it is di.cult to realize this advantage given the sensitivities of existing detectors and reasonable constraints on the instrument volume. Thus, coherent detection can be expected to play an important role in submillimeter and far - infrared astrophysics well into the future.
Adenylyl Cyclase Type 6 Overexpression Selectively Enhances ß-Adrenergic and Prostacyclin Receptor Mediated Inhibition of Rat Cardiac Fibroblast Function Due to Co-Localization in Lipid Rafts

Cardiac fibroblasts produce and degrade extracellular matrix and are critical in regulating cardiac remodeling and hypertrophy. Fibroblasts are activated by factors such as transforming growth factor β and inhibited by agents that elevate 3′,5′-cyclic adenosine monophosphate (cAMP) levels. cAMP signal generation and response is known to be compartmentalized in many cell types in part through the colocalization of receptors and specific adenylyl cyclase isoforms in lipid rafts and caveolae. The present study sought to define the localization of key G protein-coupled receptors with adenylyl cyclase type 6 (AC6) in lipid rafts of rat cardiac fibroblasts and to determine if this colocalization Correspondence to: Rennolds S. Ostrom, rostrom@utmem.edu. NIH Public Access Author Manuscript Naunyn Schmiedebergs Arch Pharmacol. Author manuscript; available in PMC 2009 June 1. Published in final edited form as: Naunyn Schmiedebergs Arch Pharmacol. 2008 June ; 377(4-6): 359–369. doi:10.1007/s00210-007-0196-0. N IH PA Athor M anscript N IH PA Athor M anscript N IH PA Athor M anscript was functionally relevant. We found that cardiac fibroblasts produce cAMP in response to agonists for β-adrenergic (isoproterenol), prostaglandin EP2 (butaprost), adenosine (adenosine-5′-Nethylcarboxamide, NECA), and prostacyclin (beraprost) receptors. Overexpression of AC6 increased cAMP production stimulated by isoproterenol and beraprost but not by butaprost or NECA. A key function of fibroblasts is the production of collagen. Isoproterenoland beraprost-mediated inhibition of collagen synthesis was also enhanced by AC6 overexpression, while inhibition by butaprost and NECA were unaltered. Lipid raft fractions from cardiac fibroblasts contain the preponderance of βadrenergic receptors and AC6 but exclude EP2 receptors. While we could not determine the localization of native prostacyclin receptors, we were able to determine that epitope-tagged prostanoid IP receptors (IPR) expressed in COS7 cells did localize, in part, in lipid raft fractions. These findings indicate that IP receptors are expressed in lipid rafts and can activate raft-localized AC isoforms. AC6 is completely compartmentized in lipid raft domains where it is activated solely by coresident G protein-coupled receptors to regulate cardiac fibroblast function.
Evaluasi Kadar Cemaran Pb Dan Cd Dalam Air Pada Pantai Dan Daerah Perikanan Di Sekitar Kawasan Pelabuhan Tanjung Emas Semarang Dengan Metode Spektrofotometri Serapan Ato

Perairan pantai Semarang khususnya di sekitar pelabuhan Tanjung Emas berfungsi sebagai tempat budidaya ikan dan pembuangan limbah dari darat. Berdasarkan monitoring beberapa peneliti pada tahun 1984/1985 dan 1986/1987 diperoleh bukti bahwa perairan pantai Semarang telah terkontaminasi logam berat seperti Pb dan Cd. Penelitian ini bertujuan untuk menentukan ada tidaknya dan menentukan kadar cemaran dalam air pada daerah pantai dan perikanan di sekitar kawasan Pelabuhan Tanjung Emas Semarang. Air diambil dari enam stasiun pada daerah pantai dan perikanan di sekitar kawasan Pelabuhan Tanjung Emas Semarang pada bulan Maret 2012. Air diukur pHnya secara insitu dan diambil 1 L tiap stasiun kemudian diawetkan sampai pH <2. 100,0 mL air didestruksi menggunakan HNO3. Analisis menggunakan Spektrofotometri Serapan Atom (SSA). Hasil menunjukkan bahwa air pada daerah pantai dan perikanan di sekitar kawasan Pelabuhan Tanjung Emas Semarang mengandung logam Pb dan Cd. Kadar Pb berkisar berkisar (7,81±2,84)X10-2 - (2,88±0,30)X10-1 ppm dan Cd berkisar (1,63±0,03)X10-2-2,96±0,03)X10-2 ppm. Kadar Pb dan Cd pada air ini menurut Baku Mutu Air Laut Untuk Biota Laut yang ditetapkan oleh KMNLH nomor 51 tahun 2004 telah melebihi ambang batas yang ditetapkan.
The Impact of Byline Order of Corresponding Author - A Preliminary Study

Corresponding author (C-Au) holds an important position in byline order. Some papers have analyzed the contribution of C-Au, but they do not consider the variation in different byline order. Furthermore, some studies use questionnaire and found that people perception on other authors’ contribution would be influence by the byline order of C-Au, but the real situation remains unclear. Thus, this poster aims to analyze two questions: (1) What kind of byline order do C-Au have and are their contribution influenced by their byline order? (2) Are other authors contributions influenced by the byline order of C-Au? Three main findings emerge: firstly, the last author are not always to be C-Au; following with the decline of byline order of C-Au, the contribution of C-Au deceases; finally, as the byline order of C-Au changes, other authors’ contribution change significantly. For instance, second author has the lowest contribution when the last author is C-Au.
(M, N)-exponential model in the theory of excitons

The one- exponential excitonic model, widely used in the theory of light propogation through spatially dispersive media, is generalized in order to take into account the simultaneous existing of M exciton states and N transport mechanisms. The physical reason and possibilities of the proposed model is demonstrated on the base of the Frenkel exciton. The model essentially extends the area of the possible applications consarving at the same time the exact solubilities and other advantages of the traditional exponential-like approches for the case of the bounded media. The model is used in the paper for deriving the balance equations of the energy density and the energy flux density as well as for studing of boundary value and some other crystal optics problems near the excitonic resonances.
Using the geneFISH to detect archaeal amoA genes in microbial mats and biofilms

In present study, the geneFISH was used to detect archaeal amoA gene in microbial mats and MRC biofilms at different locations. To get this aim, clone libraries of archaeal 16S rRNA and amoA genes were constructed in different layers Sippewissett Salt Marsh microbial mats and Marine Resources Centre (MRC) biofilms collected at different locations were investigated. Community structures analysis indicated the MRC2 and MRC4 biofilms collected from MRC seawater inlet tubes form a special environment for Crenarchaea, where Crenarchaea as the dominated Archaea groups, while the microbial mats were dominated by Euyarchaea, and only few Crenarchaea were detected. The CARD-FISH counting indicated that only 5.7 to 15.6% and 3.5 to 26.2% of the total cells represented as the Archaea in microbial mats and MRC biofilms, respectively; while less than 1% and 9% of total cells represented as Crenarchaea in microbial mats and MRC biofilms. Based on the amoA genes clone libraries in MRC biofilms, two specific amoA genes targeted probes were designed for geneFISH. However, due to the low abundances of Crenarchaea and complex background in our research samples, only weak and potential signals of amoA gene probes were detected from MRC4 biofilms sample. Thus, based on these weak signals, the primary result of geneFISH indicated at least 25% of Crenarchaea harbored amoA gene, which might be catalyzing the oxidation of ammonia.
IN VITRO EVALUATION OF EXPERIMENTAL FLUORIDE TAPE IN INHIBITION OF ENAMEL DEMINERALIZATION

The aim of this in vitro study was to evaluate the effectiveness of experimental 2.26% fluoride-polyvinyl alcohol (F-PVA) tape in inhibition of enamel demineralization using enamel surface microhardness (SMH) analysis and scanning electron microscopy (SEM) examination. Enamel specimens (n=60) randomly assigned to four groups: control group, F-PVA tape group, fluoride varinish (F-varnish) group, casein phosphopeptide-amorphous calcium phosphate (CPP-ACFP) group. After topical application, pH-cycling was processed. Then, SMH was measured and the percentage loss of surface microhardness (%SML) was calculated. For the SEM examination, five sample specimens in each group were treated and the morphologic character was evaluated. After pH-cycling, the SMH values of the enamel specimens of F-PVA tape and F-varnish group were significantly higher than that of CPP-ACFP group, there was no significant difference between F-PVA tape and Fvarnish group. With SEM examination, enamel surfaces in the F-PVA tape group and F-varnish group showed numerous spherical and ovoid crystals formed on the enamel surface were also observed. The density of crystals was higher than that of both control group and CPP-ACFP group. F-PVA tape is effective in inhibition of enamel demineralization. Also, F-PVA tape’ s inhibition of enamel demineralization is comparable to that of F-vanish and greater than that of CPP-ACFP.
Energy exchange analysis in droplet dynamics via the Navier–Stokes–Cahn–Hilliard model

We develop the energy budget equation of the coupled Navier–Stokes–Cahn–Hilliard (NSCH) system. We use the NSCH equations to model the dynamics of liquid droplets in a liquid continuum. Buoyancy effects are accounted for through the Boussinesq assumption. We physically interpret each quantity involved in the energy exchange to gain further insight into the model. Highly resolved simulations involving density-driven flows and the merging of droplets allow us to analyse these energy budgets. In particular, we focus on the energy exchanges when droplets merge, and describe flow features relevant to this phenomenon. By comparing our numerical simulations to analytical predictions and experimental results available in the literature, we conclude that modelling droplet dynamics within the framework of NSCH equations is a sensible approach worthy of further research.
Zassenhaus varieties of general linear Lie algeb

Let g be a Lie algebra over an algebraically closed field of characteristic p > 0 and letU(g) be the universal enveloping algebra of g. We prove in this paper for g = gln andg = sln that the centre o U(g) is a unique factorisation domain and its field of fractions is rational. For g = sln our argument requires the assumption that p n while for g = gln it works for anyp. It turned out that our two main results are closely related to each other. The first one confirms in type A a recent conje A. Braun and C. Hajarnavis while the second answers a question of J. Alev.  2005 Elsevier Inc. All rights reserved.
The power of some standard tests of stationarity against changes in the unconditional variance

Abrupt changes in the unconditional variance of returns have been recently revealed in many empirical studies. In this paper, we show that traditional KPSS-based tests have a low power against nonstationarities stemming from changes in the unconditional variance. More precisely, we show that even under very strong abrupt changes in the unconditional variance, the asymptotic moments of the statistics of these tests remain unchanged. To overcome this problem, we use some CUSUM-based tests adapted for small samples. These tests do not compete with KPSS-based tests and can be considered as complementary. CUSUM-based tests confirm the presence of strong abrupt changes in the unconditional variance of stock returns, whereas KPSS-based tests do not. Consequently, traditional stationary models are not always appropriate to describe stock returns. Finally, we show how a model allowing abrupt changes in the unconditional variance is well appropriate for CAC 40 stock returns.
Enhancement of Bifidobacterium pseudocatenulatum G4 Adhesion Properties by Calcium Ions

Adhesion to human intestinal cell is considered as one of the main selection criteria of a probiotic strain. The adhesion of Bifidobacteriun pseudocatenulatum G4 was evaluated on HT-29 human epithelium cell–line, at four different pH and three different duration times with and without the present of calcium ions. The strain exhibited a high calcium dependent adhesive property and the unique properties of calcium ions promote both specific and non-specific interactions. A specific change of bacterial adhesion on HT-29 cell line was exhibited with the shift of pH value from 6.8 to 5.6 which simulated the rectum and ascending colon region respectively. B. pseudocatenulatum G4 is capable to adhere on human intestinal cell, promoting the strain as effective probiotic strain for in vitro and in vivo with the present of calcium.
Epidemiological Study of Neonatal Bacterial Meningitis: Moroccan Data

Neonatal bacterial meningitis has a mortality rate that exceeds 10% and is responsible for sequelae in 20-50% of cases. The epidemiology of bacterial meningitis is variable depending on the age, areas and periods. Aim of the study: To study the incidence of neonatal meningitis, know the evolution of bacterial epidemiology and risk factors. Population and methods: A retrospective study about 60 cases of neonatal meningitis over a period of 3 years (January 2011-December 2013) at the National Reference Centre for Nutrition and Neonatology of the Children's Hospital of Rabat. Results: The prevalence of neonatal bacterial meningitis was 0.5 per 1000 live births. Parturients were aged between 21 and 35 years in 50% of cases. They were illiterate in 65% of cases. The pregnancies were followed in 60% of cases. Families were from urban environment in 70% of cases. Primiparity was noted in 69% of mothers. We had vaginal delivery in 80% of women. The Apgar was <7 to 20% of newborns. The average age was 4 days with extremes of 2 and 23 days. The sex ratio was 1. Were preterm children in 42% of cases of low birth weight in 93% of cases. The average age at diagnosis was 2 day +/- 1. Neonatal bacterial meningitis were due to Escherichia coli in 45% of cases followed by group B streptococcus (GBS), which represents 2% of germs involved. Blood culture was positive in 60% of patients. They were congenital anomalies associated in 13% of cases. Low birth weight, failure monitoring pregnancy and the presence of congenital malformations were risk factors significantly associated with the occurrence of neonatal bacterial meningitis. The death occurred in 8% of cases. Conclusion: Neonatal bacterial meningitis was significantly related to adverse socio-economic conditions.
Qualities of goat semen in Tris-Citrate-Glucose extender containing glutathione

Glutathione (GSH) 0 (control), 2, 4 and 8 mM was used in the preservation of chilled goat semen. Treated and control samples were kept at 4 – 5°C up to seven days. Sperm motility and acrosome abnormality were assessed daily under phase contrast microscope. The sperm motility was significantly (P<0.01) higher in the semen treated with 8 mM GSH. Optimum sperm motility (≥50%) for artificial insemination was retained for three days with 2 and 4 mM GSH and up to four days with 8 mM GSH. Acrosomal damage was significantly (P<0.01) reduced to ≤ 1.0% after addition of 8 mM GSH. It is suggested that GSH may be used as an antioxidant for better preservation of goat semen for artificial insemination. DOI: 10.3329/bvet.v27i2. 7554 Bangl. vet . 2010. Vol. 27, No. 2, 46 – 55
CORPORATE SOCIAL RESPONSIBILITY A KEY FOR BUILDING A STRONG BRAND IN GHANA

In recent years, the increased application of technology has increased competition and crowded markets with little product differentiation. Hence, the public is now vigilant on what firms are saying about their corporate social responsibility (CSR) and what they are doing in practice. Undoubtedly, in Ghana, the Media, Civil Society and Government are increasingly admonishing businesses to be socially responsible, to the extent that business stakeholders are now more interested in protecting their reputation and brand image and by promoting business sustainability through making conscious efforts to maintain their corporate social responsibilities. The study is aimed at examining Corporate Social Responsibilities as a tool for building a strong brand image of an organization. A survey method was used in which data was collected through questionnaires. The results established that CSR influences consumers’ perception of the company positively and also gives an appealing image to the company. The results further showed that customers consider CSR as an important factor in buying decision making and are a bit more willing to buy from a company which is actively involved in CSR.
Feeding ecology of Bathyraja macloviana (Rajiformes, Arhynchobatidae): a polychaete-feeding skate from the South-west Atlantic

The present paper analyses the diet, feeding strategy and niche width of B. macloviana in a sector of the Argentinean Continental Shelf (ACS). Individuals (n = 147) were collected from 43 sampling stations in late summer and autumn 2001. Thirty one alimentary items in the gut contents were found, with a clear dominance of polychaetes. Crustaceans were secondary alimentary items. The polychaete Travisia kerguelensis was the main food item ingested, followed by Nepthyidae, Sabellidae and Lumbrineridae, while Gammaridae and Cirolanidae were the main items among crustaceans. The niche width and feeding strategy displayed by B. macloviana support the specialisation towards polychaetes throughout this study. Slow motile and infaunal species constitute major preys. The results suggest that this skate actively selects worms, reflecting, in some sense, the composition of the polychaete assemblage, and allowing a low dietary overlap with other sympatric skates of the ACS.
Analysis and Application of Decaying Turbulence with Initial Fractal Geometry

In this paper, we address high‐Schmidt‐number (Sc) scalar turbulent mixing that results from grid‐generated turbulence using the initial fractal geometry of the velocity pro‐ file. More specifically, as was proposed in our recent study, we adopt an initial flow field generated by a fractal grid and apply it to a water channel experiment based on a high‐Sc‐number scalar‐mixing layer in order to create grid‐generated turbulence, and thus solve our current research problem. The high‐Sc‐number scalar and velocity fields of the grid‐generated turbulence are then measured using planar laser‐induced fluo ‐ rescence (PLIF) and particle image velocimetry (PIV), respectively. By means of fractal analysis, this study specifically addresses the turbulent mixing phenomena in which the fractal dimension of the mixing interface of an observed high‐Sc‐number scalar field is calculated. Additionally, we discuss the efficiency of using fractal grids as devices for enhancing high‐Sc‐number scalar turbulent mixing by observing turbulent intensities and dissipation by PIV.
Are Lipoxygenases Valid Targets of Cancer Prevention and Treatment

Bioactive arachidonic acid (AA) metabolites produced by lipoxygenases (LOXs), and to a certain extent the LOX enzymes themselves, has been implicated in cancer development and progression. LOX enzymes and their AA metabolites have been shown to both promote and suppress cancer. In vitro and in vivo studies have shown that 5-LOX and p12-LOX promote tumor formation and progression, while 15-LOX-2 suppresses tumor progression. 15-LOX-1’s role in cancer appears to be tissue dependent; inhibition of 15-LOX-1 suppresses tumors in some tissues while promoting tumors in other tissues. Further research on the roles of lipoxygenases in cancer is needed to develop new approaches to cancer prevention and treatment.
Brazilian Regulation in Pharmacovigilance: A Review

Brazilian health legislation on drug surveillance has been available for only four decades. This study aimed to analyze the chronological evolution of the pharmacovigilance legislation in Brazil. A critical review of the legislations and communications published between 1976 and 2015 was conducted. Sixty-two (62) documents were identified. Advancements in the assessment of health technologies occurred only after the publication of the National Drug Policy (1998), the foundation of the National Health Surveillance Agency (ANVISA), and the creation of the National Center for Drug Monitoring (2001). From 2009, pharmacovigilance practices became mandatory for marketing authorization holders. Despite recent, the regulatory advancements in pharmacovigilance in Brazil are equivalent to international practices. However, there is still a lack of regulations for biosimilars and veterinary medicines, of agility in reporting non-serious risks to manufacturers and health care services, and of encouragement for reporting technical complaints and quality deviations, which could improve and control post-marketing drug quality. It is necessary to encourage and develop strategies for the decentralization of pharmacovigilance actions to the whole country.
A new bacilliform virus in Australian Cherax destructor (Decapoda: Parastacidae) with notes on Cherax quadricarinatus bacilliform virus (= Cherax baculovirus)

lntranuclear lesions were detected in hepatopancreocytes of Cherax destructor by light microscopy. The les~ons included nuclear hypertrophy, chromatin margination, a peripherally displaced nucleolus, or nucleolar remnants remaining in the centre of a granular eosinophilic inclusion. The cytoplasm of some infected cells was granular and basophilic. The intensity of the lesions was low in all cases; however, infected nuclei were sloughed from the epithelium. Rod-shaped virions within a granular viroplasm were visualised in these nuclei by electron microscopy. The virions contained a nucleocapsid, consisting of an electron-dense nucleoprotein core and less electron-dense capsid, and a trilaminar envelope. The envelope was closely applied, except that at one end it was laterally expanded to contain a tail-like structure that arose from the nucleocapsld. The nucleocapsid was often bent in this region. Capsids formed unassociated with membranes. A capsid which was partially filled with nucleoprotein was elongated and improperly enveloped. Virions were 68 X 304 nm and nucleocapsids were 49 X 263 nm. Virions of Cherax quadricarinatus bacilliform virus cons~sted of a rod. -shaped nucleocapsid surrounded by a loosely applied trilaminar envelope. A nucleocapsld tail-like structure was visible in several virions. Capslds appeared to form inside of membrane bubbles and capsids that were partially filled with nucleoprote~n had a central filament. Vlrlons were 103 X 262 nm and nucleocapsids were 54 X 212 nm. The morphology and development of both viruses is compared to other arthropod bacill~form viruses.