Miracle-dz/UniFAR-FTUs huggingface dataset:
Performance evaluation of reliable communications for wireless in-body sensor networks

Wireless in-body sensor networks are attracting increasing attention for numerous healthcare applications and medical services. Implant devices are widely employed to measure physiological signals inside the human body in a simple, long lifetime and continuous approach. However, due to the strict technical requirements of implant devices, there exist numerous key research challenges in this area. Considering realistic transmission power requirements based on the IEEE 802.15. 6 standard safety regulations, the channel characteristics of implant to deep implant and implant to body surface communication scenarios are investigated. Furthermore, multiple vital quality of service (QoS) factors of implant communication channels are studied regarding channel capacity, bit error rate (BER), link quality and data rate. The system performance evaluation indicates that the data transmission rate can be optimized up to 10 Mbps. Furthermore, the transmission distance supported by in-body to on-body communication path is 2 meters, at 1 µW while the in-body to deep tissue region communication channel achieves less than 1 meter. The results proposed in this paper give an outlook of the intra-body networking system performance and can be applied to in-body communication system implementation research.
The essential role of insulin-like growth factor-1 in the intestinal tropic effects of glucagon-like peptide-2 in mice.

BACKGROUND & AIMS Glucagon-like peptide-2 (GLP-2) is an intestinal hormone that acts through unknown pathways to induce intestinal growth. We investigated the role of the insulin-like growth factors (IGF-1 and IGF-2) as mediators of GLP-2-enhanced growth in the murine intestine. METHODS IGF-1 expression and secretion were determined in GLP-2-responsive primary intestinal cultures treated with GLP-2. Parameters of intestinal growth were assessed in wild-type (CD1, Igf1(+/+) and Igf2+), heterozygous (Igf1(+/-)), and null (Igf1(-/-) and Igf2(-P)) mice treated chronically with saline, GLP-2, IGF-1, or R-Spondin1. RESULTS GLP-2 increased IGF-1 messenger RNA expression and IGF-1 secretion in intestinal cultures and increased expression of IGF-1 messenger RNA in mouse small intestine in vivo. Igf1(+/+) and Igf2+ mice responded to . 1 microg/g(-1) per day(-1) GLP-2 with increased intestinal weights, morphometric parameters, and proliferative indices. In contrast, Igf1(-/-) mice were unresponsive to the same dose of GLP-2, failing to demonstrate changes in intestinal weight, morphometry, or proliferation. However, a significant effect of 1 microg/g(-1) per day(-1) GLP-2 was observed in Igf1(-/-) mice, but only in terms of small intestinal weight when normalized for body weight. Furthermore, Igf2(-P) mice demonstrated a partially impaired response in terms of small intestinal growth. Both Igf1(-/-) and Igf2(-P) mice exhibited normal-enhanced intestinal growth in response to IGF-1 and/or R-Spondin1. CONCLUSIONS GLP-2 enhances intestinal IGF-1 expression and secretion, and IGF-1 is required for small and large intestinal growth in response to GLP-2. These findings identify IGF-1 as an essential mediator of the intestinotropic actions of GLP-2.
Becoming Bionic

Imagine a piece of technology that would let you control an apparatus simply by thinking about it. Lots of people, it turns out, have dreamed of just such a system, which for decades has fired the imaginations of scientists, engineers, and science fiction authors. It's easy to see why: By transforming thought into action, a brain-machine interface could let paralyzed people control devices like wheelchairs, prosthetic limbs, or computers. Farther out in the future, in the realm of sci-fi writers, it's possible to envision truly remarkable things, like brain implants that would allow people to augment their sensory, motor, and cognitive abilities.
Overall fibromyalgia pain is predicted by ratings of local pain and pain-related negative affect--possible role of peripheral tissues.

OBJECTIVES Despite variable numbers and intensities of local pain areas, fibromyalgia (FM) patients can provide overall clinical pain ratings. We hypothesized that the overall clinical pain is largely determined by the pain intensity of local body areas. Thus, we assessed the role of local body pains as predictors of overall clinical pain in FM patients. METHODS Ratings of overall clinical pain intensity and pain-related negative affect (PRNA) were obtained from 277 FM patients. In addition, the patients identified painful body areas by shading a body pain diagram and rated the intensity of each pain area using a mechanical visual analogue scale (VAS). Hierarchical regression analyses were used to examine predictors of overall clinical FM pain intensity including PRNA, number of local pain areas, and maximal/average intensity of local pain areas. RESULTS The average overall clinical pain rating of all FM patients was 4.6 (S.D. 2.3) VAS. The PRNA accounted for 19%, number of painful body areas for 9% and maximal/average local pain for 27% of the variance of overall clinical FM pain (P-values < 0.001). The combination of all factors predicted 55% of the variance in overall clinical pain intensity of FM patients. CONCLUSION Peripheral factors (maximal/average local pain and number of painful body areas) predicted most of the variance of overall clinical FM pain, suggesting that the input of pain by the peripheral tissues is clinically relevant. About 19% of the pain variance was predicted by PRNA. Thus, peripheral pain and negative affect appear to be particularly relevant for overall FM pain and may represent important targets for future therapies.
Inter-Domain QoS Provisioning and Accounting

QoS[QOS]-capable communication network devices are now available, such as IP routers and switches, thus enabling the implementation of QoS-guaranteed services. Policy-Based Network Management (PBNM) is a framework to control these network devices with management rules that are called "Policy". At present, most network engineers on PBNM cope with only intradomain QoS-guaranteed services, but an enhanced framework for interdomain QoS-guaranteed services is required for real commercial networks that communicate with networks managed with a different policy. On real commercial networks, service providers have to charge customers for the interdomain QoS-guaranteed services. We focus on interdomain QoS provisioning and accounting. First, we discuss the policy framework and its architecture. Based on this framework and architecture, we propose two protocols: a Policy Advertisement Protocol (PAP) that distributes local policies among domains, and a Policy Negotiation and Notification Protocol (PNP) that sets up a QoS-guaranteed communication path among domains[INTD]. Our experimental network confirms that this interdomain QoS provisioning is effective when service providers provide interdomain QoS services from the point of view of network administrator’s tasks, performance, and network traffic.
[Cystic fibrosis: a microbiological study over an 8-year period].

OBJECTIVE To study the microbiology of cystic fibrosis in our hospital for the period from 1985 to 1992. MATERIAL AND METHODS The number of samples analyzed totalled 1,034, most of which were sputum and nasopharyngeal aspirates belonging to 113 patients (49 women and 64 men). The average age was 10 years (range: 15 days-33 years). RESULTS AND DISCUSSION Only 1.7% of the samples were negative. Normal flora were found in 10.8% and one or more potentially pathogenic microorganisms were found in the remaining 87.4%. Colonies were over 10(6) UFC/ml in size in 77.8% of the quantified cultures. The most frequently identified microorganisms in the population overall were P. aeruginosa (53.9%), S. aureus (30.3%) and H. influenzae (22.0%). In patients less than 12 months old, however, the most common isolations were of S. pneumoniae and B. catarrhalis; cultures from patients older than 16 years old most often yielded filiform fungi, mainly Aspergillus spp. We found no strains of Legionella spp. and P. cepacia was found in only 3 cases, in which the clinical outcome was good. In addition to the 3 most common organisms, we recorded several consecutive isolations of Proteus mirabilis, Xanthomonas maltophilia and Serratia marcescens in patients older than 11 years old; this finding suggests that given the improved survival of cystic fibrosis patients over the coming years and the antibiotic pressure placed on them, there may be slight changes in the bacterial ecology typical of this disease. No strain of S. aureus proved resistant to methicillin, but P. aeruginosa was shown to be resistant to gentamycin (58.2%) among the aminoglycosides and also to some of the beta-lactams considered to be effective, as follows: 25.2% to piperacillin, 22.6% to ceftazidime and even 19.8% to aztreonam. There was slight resistance of ciprofloxacin (6.3%).
Innovation capability development: case studies of small enterprises in the LMT manufacturing sector

ABSTRACT Competitiveness in lower tech, small-to-medium sized enterprises (LMT-SMEs) depends as much on innovation as it does in high tech, larger counterparts. For many decades, innovation studies have focused on the latter sector that is differentiated from the former in one key respect – business investment in research and development (BERD). LMT-SMEs have low reported BERD and according to the OECD spend less than 3% of turnover on R&D. This figure masks hidden investments in non-traditional innovation that often goes unreported by managers. Adopting a case study approach, this research seeks to address two questions: ‘what innovation is occurring within LMT-SME’ and ‘what are the capabilities developed that support innovation activity’, allowing such firms to dynamically adapt to external environment turbulence. In exploring these issues, this study goes some way towards bridging the gap in the understanding of innovation in this often ‘forgotten sector’ [Hirsch-Kreinsen, H. , & Jacobson, D. (Eds.). (2008). Innovation in low-tech firms and industries. Cheltenham: Edward Elgar].
Drivers and barriers to using servicescape in storytelling: a case from the tourism industry

There is a growing interest in creating positive experiences for consumers, especially in the tourism industry. Our context is farm tourism. One way to enhance the customer experience is by telling good stories (Mossberg, 2008). By linking the story to the servicescape, the stories will be even more effective at creating extraordinary experiences (Mossberg, 2008). Limited research has been conducted on the use of servicescape, and as far as we know, no study has yet investigated drivers and barriers to using servicescape in storytelling. However, these barriers and drivers might have an influence on the tourism provider’s use of the servicescape in storytelling. The research method chosen in this thesis was an explorative study with the use of in-depth interviews. Our interview guide was semi-structured. We found that there were several drivers and barrier to using the servicescape in storytelling. These were connected to authenticity, interest, knowledge, and resources. Authenticity was found to be important for the tourism provider, which is in line with research regarding this same topic from the perspective of tourists (Mossberg & Johansen, 2008). However, even though tourists demand only stories that can be perceived as authentic, it was not possible for the tourism provider to present stories connected to the servicescape that were not true. On the other hand, economy is a barrier for utilising and developing the servicescape, and will influence the way in which it can be used in storytelling. Furthermore, by using resources to develop the servicescape, economy will act as a driver for linking the latter to the stories. A link between the storytelling and the servicescape will influence the customer in a one-time purchase in a better way (Gilliam & Zablah, 2013). Furthermore, we found that knowledge is also a driver and a barrier for using the servicescape in storytelling. As a driver, knowledge about the history of the farm makes it easier for the tourism provider to make use of the servicescape. Lack of knowledge, on the other hand, will be a barrier to integrating the servicescape in storytelling. The tourism provider’s interest in the story is a driver for using the servicescape in storytelling. Knowledge and interest are important to tell a story in an effective way. The results of our research can help tourism providers to identify which of the drivers and barriers affect their use of the servicescape in storytelling. These providers can then seek to overcome the barriers and utilise the drivers, and in the end, tell better stories using the
REVIEW PENELITIAN TENTANG EARNINGS MANAGEMENT TERHADAP KINERJA PERUSAHAAN

Abstract Finance Information to company represent one of the information regarding hit the condition of company especially information having the character of finance, the information elementary serve the purpose of in performance assessment of an company. relevant information in obtainable performance assessment from balance report, because during the time size measure of erformance relied on by a profit acquirement of company report of company Balance of be of benefit to investor especially for the decision making of invesment, this matter relate to the return expected will be obtained by investor (return ekspektasi). For the reason management try to arrange the profit presented, that is by improving profit reported so that company performance seen nicely. The action recognized by earnings is management. here are some definition of concerning earnings management and also some research of related to this earnings management, breakdown of in detail regarding the earnings management and also issue of related to earnings management will be presented at solution shares. Intention of this article writing is mereview of some research of concerning earnings management, and finally from some the review research of dambil conclusion of about this earnings management will be able to influence the performance of an company. Keywords : company performance, earning management
The practices of fair value reporting on investment property in Malaysia

The adoption of FRS 140 Investment Property has introduced the application of fair value accounting for non financial assets for the first time. However, the decision to allow such options appears to be contentiously debated as fair value measurement is not easily determined.Accordingly, this study examines the value relevance of fair value accounting which embraced under the accounting standard FRS 140 in the context of Malaysia.The finding supports the view that lack of explanation on fair value, disclosing outdated fair value and high measurement error lead to the perception of investors do not distinguish the value of companies just based on the fair value information. However, model of measurement and source of valuation is perceived differently by investors in setting the share price of companies. Surprisingly, there is no significant difference between valuations of investment property fair value either conducted by directors or independent valuers.
Information Privacy Concerns and E-Commerce: An Empirical Investigation

E-business industry and consumers are struggling to find a balance between consumers' privacy and the promotion of the development of online business. Regulation has widely been considered as an appropriate way to resolve regulatory conflicts in e-commerce. A multitude of surveys have investigated privacy attitudes, revealing a general desire among Internet users to protect their privacy. This paper concentrates on the tension between e-commerce, privacy concerns, and user behavior in Austria with a special focus on the detection of demographic attributes that influence users' perception of privacy issues. The authors present both a conceptual framework and empirical findings pertaining to privacy awareness and user behavior. Our results show that the willingness to provide personal data over the Internet to a certain extent depends on (socio-) demographic characteristics such as gender, knowledge, and experience.
A New Linear Vernier Permanent-Magnet Machine Using High-Temperature Superconducting DC Field Excitation

In this paper, a new linear Vernier permanent-magnet machine is proposed. By using high-temperature superconducting (HTS) winding to provide an additional field excitation, a hybrid excitation machine is achieved. The HTS field winding is accommodated in the stator and PMs are mounted on the mover surface. By regulating the dc current flowing in the HTS field winding, the air-gap flux can be flexibly controlled. First, the proposed machine and the cooling system for the HTS field winding are presented. Second, the operating principle of the proposed machine is discussed. Third, by using the 3-D finite element method, the performance of the proposed machine is evaluated. Finally, a conclusion is drawn.
Approximations of multiobjective optimization for dynamic spectrum allocation in wireless sensor networks

This paper considers the problem of the centralized spectrum allocation in wireless sensor networks towards the following goals: (i) maximizing fairness, (ii) maximizing spectrum utilization, (iii) reflecting the priority among sensor data, and (iv) avoiding unnecessary spectrum handoff. We cast this problem into a biobjective mixed integer nonconvex nonlinear programming that is absolutely intractable to solve at least globally without any aid of conversion and approximation. We tackle this intractability with convexification, scalarization, and rounding method that yield good approximate integer solutions.
From shareholder value creation to purposeful organizations – The role of purpose for managing business

ion acted as tool to understand what sort of data I have managed to collect. Then I could dive in a bit deeper and understand from where I could find interesting information regarding my research questions. In other words which open codes are interesting for my research. For example: Research question: What kind of purposes there are and how they are defined? Related abstraction groups: Types of hybrids, Benefits of hybrids, Purpose vs profit, Differentiated hybrids, Integrated hybrids and Hybrid organizations Although most of the used open codes for this research question were found under these groups it wasn’t limited to them. The same logic was used for each research question individually after which I started creating explanatory categories that are abstractive features of phenomena relating
The Relationships among Academic Stress, Major Satisfaction, and Academic Achievement according to Type of Achievement Goal Orientation in Nursing Students

The purposes of this study were to determine the types of achievement goal orientation exhibited by nursing students and to analyze the relationships among achievement goal orientation, academic stress, major satisfaction, and academic achievement in such students. Data were collected from 231 sophomore and junior nursing students, and analyzed through descriptive statistics and Pearson’s correlation analyses, with SPSS WIN 18.0. Academic stress was higher in students with performance avoidance orientation than those with performance approach or mastery approach orientations. General satisfaction with major was higher in students with mastery approach orientation than those with performance avoidance orientation. The findings show the necessity of identifying the type of academic achievement goal orientation in nursing students.
Cyanidin Chloride inhibits ovariectomy‐induced osteoporosis by suppressing RANKL‐mediated osteoclastogenesis and associated signaling pathways

Over‐production and activation of osteoclasts is a common feature of osteolytic conditions such as osteoporosis, tumor‐associated osteolysis, and inflammatory bone erosion. Cyanidin Chloride, a subclass of anthocyanin, displays antioxidant and anti‐carcinogenesis properties, but its role in osteoclastic bone resorption and osteoporosis is not well understood. In this study, we showed that Cyanidin Chloride inhibits osteoclast formation, hydroxyapatite resorption, and receptor activator of NF‐κB ligand (RANKL)‐induced osteoclast marker gene expression; including ctr, ctsk, and trap. Further investigation revealed that Cyanidin Chloride inhibits RANKL‐induced NF‐κB activation, suppresses the degradation of IκB‐α and attenuates the phosphorylation of extracellular signal‐regulated kinases (ERK). In addition, Cyanidin Chloride abrogated RANKL‐induced calcium oscillations, the activation of nuclear factor of activated T cells calcineurin‐dependent 1 (NFATc1), and the expression of c‐Fos. Further, we showed that Cyanidin Chloride protects against ovariectomy‐induced bone loss in vivo. Together our findings suggest that Cyanidin Chloride is capable of inhibiting osteoclast formation, hydroxyapatite resorption and RANKL‐induced signal pathways in vitro and OVX‐induced bone loss in vivo, and thus might have therapeutic potential for osteolytic diseases.
Development of a RF contactless respiratory rate monitor

Radio-frequency (RF) applications are extremely common in current days, and the extension of its use to the medical field is constantly in development. One such application is the contactless and non-invasive detection of Respiratory Rate (RR). A two-antenna RF system was developed based on the measurement of the attenuation suffered by RF waves when they cross the thorax or are reflected by the chest wall. Monitoring the interference in the power of the received wave, RR was calculated with errors from 0.41 to 1.06 breaths per minute. It was concluded that the system was able to acquire RR in a precise, contactless and non-invasive way.
Recruitment of CBP/p300, TATA-Binding Protein, and S8 to Distinct Regions at the N Terminus of Adenovirus E1A

ABSTRACT The N-terminal region of the adenovirus (Ad) 12S E1A gene product targets several cellular proteins that are essential for the induction of S phase, cellular immortalization, cellular transformation, transcriptional repression, and transcriptional activation. The precise binding sites for these proteins, however, remain to be resolved. We therefore undertook an extensive site-directed mutagenesis approach to generate specific point mutants and to precisely map the binding sites for CBP, p300, TATA-binding protein (TBP), S4, S8, hGcn5, P/CAF, and Ran within the first 30 amino acids of the Ad5 12S E1A protein. We determined that although common residues within the N-terminal region can form partial binding sites for these proteins, point mutants were also generated that could discriminate between binding sites. These data indicate that AdE1A can target each of these proteins individually through distinct binding sites. It was evident, however, that the mutation of specific hydrophobic residues typically had the greatest effect upon AdE1A's ability to bind individual partners. Indeed, the mutation of L at positions 19 and 20 eliminated the ability of AdE1A to interact with any of the N-terminal binding proteins studied here. Interestingly, although TBP and S8 or CBP/p300 can exist as functional complexes, RNA interference revealed that the recruitment of either TBP, S8, or CBP/p300 to AdE1A was not dependent upon the expression of the other proteins. These data further indicate that AdE1A can target individual partner proteins in vivo and that it does not necessarily recruit these proteins indirectly as components of larger macromolecular complexes. Finally, we took advantage of the fine-mapping data to ascertain which proteins were targeted during the transformation process. Consistent with previous studies, CBP/p300 was found to be targeted by AdE1A during this process, although our data suggest that binding to other N-terminal proteins is also important for transformation.